# HG changeset patch # User proteore # Date 1579857768 18000 # Node ID 133309fd68755ff7c15b051b04c64c432cc36edc # Parent 0b279190f90d8af3779f09c7db41994a2478c592 "planemo upload commit c4edbc8a0ffd86395f088cb5b6592f77db658ac7" diff -r 0b279190f90d -r 133309fd6875 add_expression_HPA.R --- a/add_expression_HPA.R Fri Jun 28 05:01:37 2019 -0400 +++ b/add_expression_HPA.R Fri Jan 24 04:22:48 2020 -0500 @@ -146,6 +146,13 @@ } } +convert_to_previous_header <- function(options){ + header = c('Gene','description','Evidence','Antibody','RNA tissue specificity','Reliability (IH)','Reliability (IF)','Subcellular location','RNA tissue specific NX','TPM max in non-specific') + names(header) = c('Gene','description','Evidence','Antibody','RNA tissue category','Reliability (IH)','Reliability (IF)','Subcellular location','RNA TS TPM','TPM max in non-specific') + options = names(header[which(header %in% options)]) + return(options) +} + main = function() { args = get_args() @@ -175,12 +182,16 @@ check_ensembl_geneids(ids) # Read protein atlas - protein_atlas = args$atlas - protein_atlas = read_file(protein_atlas, T) + protein_atlas = read_file(args$atlas, T) # Add expression output = args$output options = strsplit(args$select, ",")[[1]] + if (tail(unlist(strsplit(args$atlas,"/")),1) == "HPA_full_atlas_23-10-2018.tsv"){ + options = convert_to_previous_header(options) + } else { + options = options[which(options != 'TPM max in non-specific')] + } res = add_expression(ids, protein_atlas, options) # Write output diff -r 0b279190f90d -r 133309fd6875 add_expression_data.xml --- a/add_expression_data.xml Fri Jun 28 05:01:37 2019 -0400 +++ b/add_expression_data.xml Fri Jan 24 04:22:48 2020 -0500 @@ -1,28 +1,41 @@ - + (RNAseq or Immuno-assays)[Human Protein Atlas] - R + R + + + + + @@ -54,12 +67,12 @@ - - + + - - + + @@ -124,7 +137,7 @@ - RNA tissue specificity abundance in 'Transcript Per Million': For each gene is reported the tissue specificity abundance in 'Transcript Per Million' (TPM) as the sum of the TPM values of all its protein-coding transcripts. -- RNA non-specific tissue abundance in 'Transcript Per Million': please refer to http://www.proteinatlas.org/about/assays+annotation#rna. +- RNA non-specific tissue abundance in 'Transcript Per Million' (only available from 23/10/2018 release): please refer to http://www.proteinatlas.org/about/assays+annotation#rna. ----- @@ -134,9 +147,13 @@ ----- -**Data sources (release date)** +**HPA source file version (release date)** + +Release date 23/10/2018: data are based on the Human Protein Atlas version 18.1 and Ensembl version 88.38 -HPA source file (data are based on the Human Protein Atlas version 18.1 and Ensembl version 88.38): http://www.proteinatlas.org/download/proteinatlas.tab.gz +Release date 21/01/2020: a subset of the data in the Human Protein Atlas version 19.1 + +downloaded from: http://www.proteinatlas.org/download/proteinatlas.tab.gz ----- diff -r 0b279190f90d -r 133309fd6875 proteinatlas.csv --- a/proteinatlas.csv Fri Jun 28 05:01:37 2019 -0400 +++ /dev/null Thu Jan 01 00:00:00 1970 +0000 @@ -1,19629 +0,0 @@ -Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence HPA evidence UniProt evidence MS evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location RNA tissue category RNA TS RNA TS TPM TPM max in non-specific -TSPAN6 T245, TM4SF6, TSPAN-6 ENSG00000000003 Tetraspanin 6 X 100627109-100639991 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004109 Approved Approved Cytosol Mixed fallopian tube: 101.0 -TNMD BRICD4, ChM1L, myodulin, TEM, tendin ENSG00000000005 Tenomodulin X 100584802-100599885 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA034961, HPA055634 Uncertain Tissue enhanced 0 adipose tissue: 10.1;seminal vesicle: 32.9 breast: 4.3 -DPM1 CDGIE, MPDS ENSG00000000419 Dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 20 50934867-50958555 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051818 Approved Expressed in all thyroid gland: 80.6 -SCYL3 PACE-1, PACE1 ENSG00000000457 SCY1-like, kinase-like 3 1 169849631-169894267 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005624 Approved Uncertain Nuclear bodies
Microtubules Expressed in all parathyroid gland: 44.0 -C1orf112 FLJ10706 ENSG00000000460 Chromosome 1 open reading frame 112 1 169662007-169854080 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023778, HPA024451 Uncertain Approved Mitochondria Tissue enhanced 0 parathyroid gland: 24.1;testis: 13.1 lymph node: 4.1 -FGR c-fgr, p55c-fgr, SRC2 ENSG00000000938 FGR proto-oncogene, Src family tyrosine kinase 1 27612064-27635277 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002024 Supported Approved Plasma membrane
Aggresome Tissue enhanced 0 appendix: 87.8;bone marrow: 137.2;spleen: 92.1 lung: 56.3 -CFH ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS ENSG00000000971 Complement factor H 1 196651878-196747504 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016385, CAB016769, HPA038922, HPA049176, HPA053326 Supported Approved Vesicles Tissue enhanced 0 liver: 838.9 gallbladder: 206.0 -FUCA2 dJ20N2.5, MGC1314 ENSG00000001036 Fucosidase, alpha-L- 2, plasma 6 143494811-143511690 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031659, HPA031660, HPA031661 Uncertain Expressed in all parathyroid gland: 152.0 -GCLC GCS, GLCL, GLCLC ENSG00000001084 Glutamate-cysteine ligase, catalytic subunit 6 53497341-53616970 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009569, HPA036359, HPA036360 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all fallopian tube: 81.9 -NFYA CBF-B, HAP2, NF-YA ENSG00000001167 Nuclear transcription factor Y, alpha 6 41072945-41099976 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009250, HPA050779 Supported Supported Nucleoplasm Expressed in all testis: 71.0 -STPG1 C1orf201, FLJ33340, MAPO2 ENSG00000001460 Sperm-tail PG-rich repeat containing 1 1 24356999-24416934 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA024301 Approved Nucleoplasm Tissue enhanced 0 testis: 46.6 fallopian tube: 26.4 -NIPAL3 DJ462O23.2, NPAL3 ENSG00000001461 NIPA-like domain containing 3 1 24415794-24472976 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039978 Approved Approved Nucleoplasm Expressed in all prostate: 94.7 -LAS1L FLJ12525 ENSG00000001497 LAS1-like, ribosome biogenesis factor X 65512582-65534775 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044431, HPA061463 Supported Approved Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all parathyroid gland: 39.9 -ENPP4 KIAA0879, NPP4 ENSG00000001561 Ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 6 46129993-46146699 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016594 Approved Expressed in all parathyroid gland: 37.8 -SEMA3F Sema4, SEMAK ENSG00000001617 Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 3 50155045-50189075 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035008 Approved Expressed in all skin: 89.3 -CFTR ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR ENSG00000001626 Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 7 117465784-117715971 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001951, HPA021939 Supported Tissue enhanced 0 gallbladder: 89.6;rectum: 50.1 colon: 47.0 -ANKIB1 DKFZP434A0225, KIAA1386 ENSG00000001629 Ankyrin repeat and IBR domain containing 1 7 92246234-92401384 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019358, HPA021780 Uncertain Supported Plasma membrane
Cytosol Expressed in all parathyroid gland: 45.4 -CYP51A1 CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1 ENSG00000001630 Cytochrome P450, family 51, subfamily A, polypeptide 1 7 92112151-92142952 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041325, HPA043508 Approved Validated Endoplasmic reticulum Expressed in all testis: 175.2 -KRIT1 CAM, CCM1 ENSG00000001631 KRIT1, ankyrin repeat containing 7 92198969-92246166 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049606 Supported Uncertain Vesicles Expressed in all testis: 48.6 -RAD52 ENSG00000002016 RAD52 homolog, DNA repair protein 12 912077-990053 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA028957 Approved Nuclear speckles
Plasma membrane Expressed in all thyroid gland: 13.5 -BAD BBC2, BCL2L8 ENSG00000002330 BCL2-associated agonist of cell death 11 64269830-64284704 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004205, HPA028185, HPA062105 Approved Validated Mitochondria Expressed in all cerebral cortex: 49.1 -LAP3 LAP, LAPEP, PEPS ENSG00000002549 Leucine aminopeptidase 3 4 17577192-17607972 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029606, HPA029607 Supported Supported Nucleoplasm
Midbody
Cytosol Expressed in all appendix: 182.0 -CD99 MIC2 ENSG00000002586 CD99 molecule X 2691179-2741309 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000020, HPA035304 Supported Approved Golgi apparatus Expressed in all gallbladder: 376.9 -HS3ST1 3OST1 ENSG00000002587 Heparan sulfate (glucosamine) 3-O-sulfotransferase 1 4 11393150-11429765 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA002237 Approved Approved Vesicles Tissue enhanced 0 gallbladder: 14.0;ovary: 23.1 urinary bladder: 5.8 -AOC1 ABP1, DAO ENSG00000002726 Amine oxidase, copper containing 1 7 150824627-150861504 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031032, HPA031033 Approved Tissue enhanced 0 placenta: 711.7;small intestine: 257.2 duodenum: 190.7 -WNT16 ENSG00000002745 Wingless-type MMTV integration site family, member 16 7 121325367-121341104 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027030 Uncertain Group enriched 5 cervix, uterine: 8.6;skin: 24.4 seminal vesicle: 3.1 -HECW1 KIAA0322, NEDL1 ENSG00000002746 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 7 43112599-43566001 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007203, HPA007593, HPA007609 Approved Supported Cytosol Tissue enhanced 0 cerebral cortex: 10.9;kidney: 8.3 testis: 3.9 -MAD1L1 HsMAD1, MAD1, PIG9, TP53I9, TXBP181 ENSG00000002822 MAD1 mitotic arrest deficient-like 1 (yeast) 7 1815793-2233243 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003635, CAB015338 Supported Supported Nucleus
Actin filaments
Cytosol Expressed in all lymph node: 23.7 -LASP1 Lasp-1, MLN50 ENSG00000002834 LIM and SH3 protein 1 17 38869859-38921770 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012072, CAB022049 Supported Supported Plasma membrane
Focal adhesion sites
Cytosol Expressed in all small intestine: 185.0 -SNX11 ENSG00000002919 Sorting nexin 11 17 48103357-48123074 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044787, HPA054660 Approved Approved Cytosol Expressed in all thyroid gland: 32.0 -TMEM176A HCA112, MS4B1 ENSG00000002933 Transmembrane protein 176A 7 150800403-150805120 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008770 Approved Approved Mitochondria Expressed in all liver: 579.4 -M6PR ENSG00000003056 Mannose-6-phosphate receptor (cation dependent) 12 8940363-8949955 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034464, HPA040445 Approved Expressed in all spleen: 178.5 -KLHL13 BKLHD2, FLJ10262, KIAA1309 ENSG00000003096 Kelch-like family member 13 X 117897813-118117340 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046039, HPA059901 Approved Approved Cytosol Tissue enhanced 0 endometrium: 52.2 smooth muscle: 43.3 -CYP26B1 P450RAI-2 ENSG00000003137 Cytochrome P450, family 26, subfamily B, polypeptide 1 2 72129238-72148038 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012567 Uncertain Approved Cytosol Tissue enhanced 0 testis: 27.2 skin: 25.1 -ICA1 ICAp69 ENSG00000003147 Islet cell autoantigen 1, 69kDa 7 8113184-8262687 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017646, HPA061452 Approved Supported Vesicles
Cytosol Mixed testis: 42.6 -DBNDD1 FLJ12582, MGC3101 ENSG00000003249 Dysbindin (dystrobrevin binding protein 1) domain containing 1 16 90004865-90020128 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043018 Approved Approved Nuclear speckles
Cytosol Tissue enhanced 0 cerebral cortex: 24.1 skeletal muscle: 15.6 -ALS2 ALS2CR6 ENSG00000003393 Amyotrophic lateral sclerosis 2 (juvenile) 2 201700554-201781189 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046588 Approved Approved Intermediate filaments
Cytosol Expressed in all cerebral cortex: 16.7 -CASP10 MCH4 ENSG00000003400 Caspase 10, apoptosis-related cysteine peptidase 2 201182881-201229406 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003780, HPA017059 Approved Uncertain Golgi apparatus
Vesicles Mixed spleen: 24.6 -CFLAR c-FLIP, CASH, CASP8AP1, Casper, CLARP, FLAME, FLIP, I-FLICE, MRIT ENSG00000003402 CASP8 and FADD-like apoptosis regulator 2 201116104-201176687 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019044, CAB022157, CAB025216 Uncertain Supported Nucleus
Nuclear bodies
Plasma membrane
Cytosol Expressed in all bone marrow: 160.5 -TFPI EPI, LACI, TFI, TFPI1 ENSG00000003436 Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 2 187464230-187565760 Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005575, CAB020842 Supported Approved Intermediate filaments
Cytosol Expressed in all placenta: 340.4 -NDUFAF7 C2orf56, MidA, PRO1853 ENSG00000003509 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 2 37231631-37253403 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045217 Uncertain Tissue enriched 5 testis: 68.6 adrenal gland: 12.9 -RBM5 H37, LUCA15 ENSG00000003756 RNA binding motif protein 5 3 50088908-50119021 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017335, HPA018011 Approved Validated Nucleoplasm Expressed in all endometrium: 112.1 -MTMR7 ENSG00000003987 Myotubularin related protein 7 8 17298030-17413528 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 23.0;parathyroid gland: 16.0 thyroid gland: 5.7 -SLC7A2 ATRC2, CAT-2, HCAT2 ENSG00000003989 Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 8 17497088-17570573 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009277 Supported Plasma membrane
Cell Junctions Tissue enhanced 0 parathyroid gland: 373.7 liver: 92.6 -ARF5 ENSG00000004059 ADP-ribosylation factor 5 7 127588345-127591705 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all skin: 176.5 -SARM1 KIAA0524, SAMD2, SARM ENSG00000004139 Sterile alpha and TIR motif containing 1 17 28364356-28404049 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024359, HPA024759 Uncertain Approved Vesicles Mixed duodenum: 7.7 -POLDIP2 DKFZP586F1524, PDIP38 ENSG00000004142 Polymerase (DNA-directed), delta interacting protein 2 17 28347177-28357522 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007700 Approved Mitochondria Expressed in all kidney: 108.5 -PLXND1 KIAA0620 ENSG00000004399 Plexin D1 3 129555175-129606818 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB020819 Approved Expressed in all placenta: 159.8 -AK2 ENSG00000004455 Adenylate kinase 2 1 33007940-33080996 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018479 Approved Expressed in all kidney: 182.0 -CD38 ENSG00000004468 CD38 molecule 4 15778275-15853230 Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002493, HPA022132, CAB025255, HPA052381 Supported Approved Plasma membrane Mixed seminal vesicle: 27.3 -FKBP4 FKBP52, FKBP59 ENSG00000004478 FK506 binding protein 4, 59kDa 12 2794953-2805423 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006148, CAB017441, HPA062857 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 107.6 -KDM1A AOF2, BHC110, KDM1, KIAA0601, LSD1 ENSG00000004487 Lysine (K)-specific demethylase 1A 1 23019448-23083689 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005884, HPA053660 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 163.3 -RBM6 3G2, DEF-3, DEF3, g16, NY-LU-12 ENSG00000004534 RNA binding motif protein 6 3 49940007-50100045 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026272, HPA027164 Supported Approved Nuclear speckles
Cytoplasmic bodies Expressed in all parathyroid gland: 82.3 -CAMKK1 CAMKKA, DKFZp761M0423, MGC34095 ENSG00000004660 Calcium/calmodulin-dependent protein kinase kinase 1, alpha 17 3860315-3894891 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009111, HPA028062 Approved Supported Cytosol Tissue enhanced 0 cerebral cortex: 51.6 seminal vesicle: 14.5 -RECQL RecQ1, RecQL1 ENSG00000004700 RecQ helicase-like 12 21468911-21501669 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009743, HPA030960, HPA064259 Supported Validated Nucleoplasm Expressed in all lymph node: 51.8 -VPS50 CCDC132, DKFZp313I2429, FLJ20097, KIAA1861, VPS54L ENSG00000004766 VPS50 EARP/GARPII complex subunit 7 93232340-93361121 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026679 Approved Uncertain Plasma membrane
Cytosol Expressed in all cerebral cortex: 25.5 -HSPB6 FLJ32389, Hsp20, PPP1R91 ENSG00000004776 Heat shock protein, alpha-crystallin-related, B6 19 35754568-35758079 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001974, HPA044153, HPA054811 Supported Tissue enhanced 0 skeletal muscle: 842.0 adipose tissue: 664.6 -ARHGAP33 FLJ39019, SNX26, TCGAP ENSG00000004777 Rho GTPase activating protein 33 19 35774532-35788822 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030117, HPA030118 Supported Approved Plasma membrane
Actin filaments
Cytosol Mixed cerebral cortex: 25.9 -NDUFAB1 ACP, FASN2A, SDAP ENSG00000004779 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 16 23581002-23596356 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054364 Uncertain Supported Nucleoplasm
Mitochondria Expressed in all heart muscle: 183.8 -PDK4 ENSG00000004799 Pyruvate dehydrogenase kinase, isozyme 4 7 95583499-95596491 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056731 Approved Expressed in all seminal vesicle: 756.5 -SLC22A16 CT2, FLIPT2, OAT6, OKB1 ENSG00000004809 Solute carrier family 22 (organic cation/carnitine transporter), member 16 6 110424687-110476641 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036902 Uncertain Group enriched 8 bone marrow: 13.0;parathyroid gland: 16.1;testis: 38.4 smooth muscle: 2.7 -ZMYND10 BLU, CILD22 ENSG00000004838 Zinc finger, MYND-type containing 10 3 50341110-50346852 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035255 Uncertain Approved Plasma membrane
Cytosol Group enriched 16 fallopian tube: 228.5;testis: 284.3 lung: 15.8 -ABCB5 ABCB5alpha, ABCB5beta, EST422562 ENSG00000004846 ATP-binding cassette, sub-family B (MDR/TAP), member 5 7 20615207-20777038 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026975 Uncertain Tissue enriched 7 epididymis: 31.7 gallbladder: 4.3 -ARX CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS ENSG00000004848 Aristaless related homeobox X 25003694-25015948 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 ovary: 41.0 skeletal muscle: 6.9 -SLC25A13 ARALAR2, CITRIN, CTLN2 ENSG00000004864 Solute carrier family 25 (aspartate/glutamate carrier), member 13 7 96120220-96322147 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018997 Approved Supported Mitochondria Expressed in all liver: 77.3 -ST7 ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7 ENSG00000004866 Suppression of tumorigenicity 7 7 116953238-117230103 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038325, HPA038326 Approved Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 50.9 -CDC27 ANAPC3, APC3, D0S1430E, D17S978E, NUC2 ENSG00000004897 Cell division cycle 27 17 47117703-47189422 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016315, HPA028129, HPA052399 Supported Validated Nucleoplasm Expressed in all thyroid gland: 71.1 -SLC4A1 AE1, CD233, DI, EPB3, FR, RTA1A, SW, WD, WR ENSG00000004939 Solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 17 44248385-44268141 Blood group antigen proteins, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015584, CAB034438, HPA063911 Supported Tissue enriched 8 bone marrow: 238.4 kidney: 29.9 -CALCR CTR ENSG00000004948 Calcitonin receptor 7 93424487-93574730 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA028962 Uncertain Tissue enhanced 0 kidney: 2.1;testis: 1.4 placenta: 0.9 -HCCS CCHL, MLS ENSG00000004961 Holocytochrome c synthase X 11111301-11123078 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002946 Approved Validated Mitochondria Expressed in all heart muscle: 31.9 -DVL2 ENSG00000004975 Dishevelled segment polarity protein 2 17 7225341-7234545 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009312, HPA021611, HPA022914, HPA064732 Approved Validated Nucleoplasm
Nuclear bodies Expressed in all ovary: 36.1 -PRSS22 BSSP-4, hBSSP-4, SP001LA ENSG00000005001 Protease, serine, 22 16 2852727-2858170 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049161 Approved Approved Nucleoplasm Tissue enhanced 0 esophagus: 14.6 tonsil: 5.7 -UPF1 HUPF1, KIAA0221, NORF1, pNORF1, RENT1, smg-2 ENSG00000005007 UPF1 regulator of nonsense transcripts homolog (yeast) 19 18831938-18868236 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019587, HPA020857 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 55.7 -SKAP2 RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R ENSG00000005020 Src kinase associated phosphoprotein 2 7 26667062-26995239 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005560, HPA024045 Supported Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 53.7 -SLC25A5 2F1, ANT2, T2, T3 ENSG00000005022 Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 X 119468400-119471319 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046835, HPA071684 Approved Supported Mitochondria Expressed in all duodenum: 791.0 -CCDC109B FLJ20647 ENSG00000005059 Coiled-coil domain containing 109B 4 109560205-109688726 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048776 Approved Approved Nucleoplasm
Cytosol Mixed lymph node: 36.7 -HOXA11 HOX1, HOX1I ENSG00000005073 Homeobox A11 7 27181510-27185223 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA006770, HPA035623 Supported Supported Nucleoplasm Tissue enhanced 0 endometrium: 96.0;smooth muscle: 67.7 cervix: 18.3 -POLR2J hRPB14, POLR2J1, RPB11, RPB11A, RPB11m ENSG00000005075 Polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 7 102473118-102478907 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042997, HPA044010, HPA046970 Approved Approved Nucleoplasm Expressed in all adrenal gland: 73.5 -DHX33 DDX33, DKFZp762F2011, FLJ21972 ENSG00000005100 DEAH (Asp-Glu-Ala-His) box polypeptide 33 17 5440912-5469060 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA073875 Supported Nucleoli Expressed in all cerebral cortex: 13.5 -MEOX1 MOX1 ENSG00000005102 Mesenchyme homeobox 1 17 43640388-43661954 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA045214 Uncertain Uncertain Nucleoli
Mitochondria Tissue enhanced 0 adipose tissue: 25.3 spleen: 16.8 -THSD7A KIAA0960 ENSG00000005108 Thrombospondin, type I, domain containing 7A 7 11370357-11832198 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000923 Supported Mixed kidney: 8.3 -LIG3 LIG2 ENSG00000005156 Ligase III, DNA, ATP-dependent 17 34980494-35009743 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006723 Supported Supported Nucleoplasm Expressed in all testis: 38.5 -RPAP3 FLJ21908, spag ENSG00000005175 RNA polymerase II associated protein 3 12 47661249-47706061 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038311, HPA038312 Approved Approved Cytosol Expressed in all lymph node: 34.9 -ACSM3 SA, SAH ENSG00000005187 Acyl-CoA synthetase medium-chain family member 3 16 20610243-20797581 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041013 Uncertain Tissue enhanced 0 liver: 93.0 kidney: 89.9 -AC004381.6 ENSG00000005189 Putative RNA exonuclease NEF-sp 16 20806429-20849668 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040755, HPA040868 Supported Approved Nuclear membrane
Nucleoli
Endoplasmic reticulum Tissue enriched 33 testis: 615.7 parathyroid gland: 18.5 -CIAPIN1 Anamorsin ENSG00000005194 Cytokine induced apoptosis inhibitor 1 16 57428169-57447528 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041350, HPA042182 Supported Supported Mitochondria Expressed in all testis: 128.4 -SPPL2B IMP4, KIAA1532, PSL1 ENSG00000005206 Signal peptide peptidase like 2B 19 2328615-2354806 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039292 Approved Nucleoplasm
Plasma membrane
Centrosome Expressed in all testis: 49.2 -FAM214B bA182N22.6, FLJ11560, KIAA1539 ENSG00000005238 Family with sequence similarity 214, member B 9 35104112-35116341 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048831, HPA055751 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all bone marrow: 24.5 -COPZ2 MGC23008 ENSG00000005243 Coatomer protein complex, subunit zeta 2 17 48026167-48038030 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055999 Uncertain Mixed adipose tissue: 73.0 -PRKAR2B PRKAR2 ENSG00000005249 Protein kinase, cAMP-dependent, regulatory, type II, beta 7 107044649-107161811 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008421 Supported Approved Golgi apparatus
Centrosome
Mitochondria
Cytosol Tissue enhanced 0 adipose tissue: 278.4 adrenal gland: 78.6 -MSL3 MSL3L1 ENSG00000005302 Male-specific lethal 3 homolog (Drosophila) X 11758159-11775753 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034535, HPA034536 Uncertain Approved Nucleoplasm Expressed in all lymph node: 60.6 -CREBBP CBP, KAT3A, RSTS, RTS ENSG00000005339 CREB binding protein 16 3725054-3880726 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004212, HPA055861 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all testis: 60.4 -BZRAP1 KIAA0612, PRAX-1, RIM-BP1, RIMBP1 ENSG00000005379 Benzodiazepine receptor (peripheral) associated protein 1 17 58301228-58328760 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024662, HPA025244 Approved Expressed in all cerebral cortex: 69.3 -MPO ENSG00000005381 Myeloperoxidase 17 58269856-58280935 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000059, HPA021147, HPA061464 Supported Supported Nucleus
Vesicles Tissue enriched 81 bone marrow: 2504.1 salivary gland: 30.8 -PON1 ESA, PON ENSG00000005421 Paraoxonase 1 7 95297676-95324707 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001610 Uncertain Tissue enriched 69 liver: 234.0 adrenal gland: 3.3 -GCFC2 C2orf3, DNABF, GCF, TCF9 ENSG00000005436 GC-rich sequence DNA-binding factor 2 2 75652000-75710989 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA077882 Supported Nucleoplasm
Cytosol Expressed in all endometrium: 17.5 -WDR54 FLJ12953 ENSG00000005448 WD repeat domain 54 2 74421678-74425755 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043257, HPA053558 Supported Approved Vesicles
Cytosol Tissue enhanced 0 fallopian tube: 111.9 testis: 47.8 -CROT COT ENSG00000005469 Carnitine O-octanoyltransferase 7 87345681-87399795 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019052, HPA019364, HPA019365 Supported Supported Vesicles Expressed in all thyroid gland: 68.1 -ABCB4 ABCB4, GBD1, MDR2, MDR3 , PFIC-3, PGY3 ENSG00000005471 ATP-binding cassette, sub-family B (MDR/TAP), member 4 7 87401697-87480435 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049395, HPA053288 Approved Approved Nucleoplasm
Plasma membrane
Actin filaments
Focal adhesion sites Tissue enriched 6 liver: 69.2 adrenal gland: 10.7 -KMT2E HDCMC04P, MLL5 ENSG00000005483 Lysine (K)-specific methyltransferase 2E 7 105014179-105114361 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022812, HPA056125 Approved Approved Expressed in all endometrium: 52.2 -RHBDD2 NPD007, RHBDL7 ENSG00000005486 Rhomboid domain containing 2 7 75842602-75888926 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045074, HPA051960 Uncertain Validated Golgi apparatus Expressed in all parathyroid gland: 253.1 -SOX8 ENSG00000005513 SRY (sex determining region Y)-box 8 16 981808-986979 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA041640, HPA058665 Approved Supported Nucleus Tissue enriched 29 cerebral cortex: 110.2 salivary gland: 3.8 -IBTK BTBD26, BTKI, DKFZP564B116 ENSG00000005700 Inhibitor of Bruton agammaglobulinemia tyrosine kinase 6 82169983-82247754 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023826, HPA048438 Uncertain Supported Nucleoplasm Expressed in all parathyroid gland: 21.0 -ZNF195 ENSG00000005801 Zinc finger protein 195 11 3339261-3379222 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030605 Uncertain Approved Nucleus
Cytosol Expressed in all epididymis: 21.2 -MYCBP2 FLJ10106, KIAA0916, PAM ENSG00000005810 MYC binding protein 2, E3 ubiquitin protein ligase 13 77044655-77327050 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039945 Uncertain Cytosol Expressed in all skin: 82.8 -FBXL3 FBL3, FBL3A, FBXL3A ENSG00000005812 F-box and leucine-rich repeat protein 3 13 76992598-77027195 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053283, HPA065626 Validated Nuclear bodies Expressed in all thyroid gland: 81.3 -ITGAL CD11A, LFA-1 ENSG00000005844 Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 16 30472658-30523185 CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025011 Supported Tissue enhanced 0 lymph node: 80.1;spleen: 82.2 appendix: 54.3 -PDK2 PDHK2 ENSG00000005882 Pyruvate dehydrogenase kinase, isozyme 2 17 50094737-50112152 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008287 Supported Supported Nucleoplasm
Mitochondria Expressed in all epididymis: 149.0 -ITGA3 CD49c, GAP-B3, MSK18, VCA-2, VLA3a ENSG00000005884 Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 17 50055968-50090481 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008572, CAB018594 Supported Supported Plasma membrane Mixed lung: 99.1 -ZFX ZNF926 ENSG00000005889 Zinc finger protein, X-linked X 24149173-24216255 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA001748, HPA003877, HPA071863 Supported Approved Nucleoplasm
Nucleoli Expressed in all parathyroid gland: 32.5 -LAMP2 CD107b ENSG00000005893 Lysosomal-associated membrane protein 2 X 120427827-120469365 CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005272, HPA029100 Supported Expressed in all gallbladder: 223.9 -ITGA2B CD41, CD41B, GP2B, PPP1R93 ENSG00000005961 Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 17 44372180-44389505 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018611, HPA031168, HPA031169, HPA031170, HPA031171 Supported Uncertain Nucleoplasm
Cell Junctions
Cytosol Tissue enhanced 0 bone marrow: 11.2;epididymis: 28.6 testis: 4.4 -ASB4 ASB-4 ENSG00000005981 Ankyrin repeat and SOCS box containing 4 7 95478444-95540232 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055240 Uncertain Group enriched 10 adrenal gland: 50.4;skeletal muscle: 11.5 placenta: 2.9 -GDE1 MIR16 ENSG00000006007 Glycerophosphodiester phosphodiesterase 1 16 19501689-19522145 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA074747 Approved Nucleus
Nucleoli
Vesicles Expressed in all parathyroid gland: 68.8 -C19orf60 FLJ20850, FLJ30108, FLJ34606, FLJ37391 ENSG00000006015 Chromosome 19 open reading frame 60 19 18588685-18592336 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043414 Approved Approved Vesicles Mixed skeletal muscle: 22.2 -CRLF1 CISS, CISS1, CLF, CLF-1 ENSG00000006016 Cytokine receptor-like factor 1 19 18572220-18607741 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041493, HPA041793 Approved Tissue enhanced 0 cerebral cortex: 17.2;placenta: 16.7 adipose tissue: 10.0 -OSBPL7 MGC71150, ORP7 ENSG00000006025 Oxysterol binding protein-like 7 17 47807372-47821834 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036076, HPA053083 Uncertain Approved Nucleoplasm
Cytosol Mixed stomach: 33.4 -TMEM98 DKFZP564K1964 ENSG00000006042 Transmembrane protein 98 17 32927910-32945106 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA040473, HPA053385 Uncertain Supported Nucleoplasm Expressed in all ovary: 237.4 -YBX2 Contrin, CSDA3, MSY2 ENSG00000006047 Y box binding protein 2 17 7288252-7294615 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012332, HPA053904, HPA056744 Supported Supported Nucleoli fibrillar center Tissue enriched 64 testis: 384.9 adipose tissue: 6.0 -KRT33A Ha-3I, Krt1-3, KRTHA3A ENSG00000006059 Keratin 33A, type I 17 41346092-41350812 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055194 Supported Group enriched 13 esophagus: 1.4;testis: 1.5 breast: 0.1 -MAP3K14 FTDCR1B, HS, HSNIK, NIK ENSG00000006062 Mitogen-activated protein kinase kinase kinase 14 17 45263121-45317040 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA027270 Supported Nucleus
Nucleoli fibrillar center
Vesicles
Cytosol Expressed in all lymph node: 23.2 -ABCC8 ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2 ENSG00000006071 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 11 17392885-17476845 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level CAB011451, HPA042318 Approved Approved Nucleoli
Golgi apparatus
Cytosol Tissue enhanced 0 cerebral cortex: 11.7 adrenal gland: 7.6 -CACNG3 ENSG00000006116 Calcium channel, voltage-dependent, gamma subunit 3 16 24255553-24362801 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059010 Approved Tissue enriched 28 cerebral cortex: 42.6 adrenal gland: 1.5 -TMEM132A FLJ20539, GBP, HSPA5BP1 ENSG00000006118 Transmembrane protein 132A 11 60924463-60937159 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051979, HPA060492 Supported Approved Mitochondria Tissue enhanced 0 cerebral cortex: 94.5 placenta: 24.9 -AP2B1 ADTB2, CLAPB1 ENSG00000006125 Adaptor-related protein complex 2, beta 1 subunit 17 35578046-35726409 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017631, HPA056733 Approved Supported Vesicles Expressed in all parathyroid gland: 260.8 -TAC1 NKNA, NPK, TAC2 ENSG00000006128 Tachykinin, precursor 1 7 97731908-97740472 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB004588, HPA014429 Approved Tissue enhanced 0 cerebral cortex: 78.0;spleen: 47.6 appendix: 13.5 -ZNF263 FPM315, ZKSCAN12, ZSCAN44 ENSG00000006194 Zinc finger protein 263 16 3263800-3301401 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035085, HPA035086 Uncertain Supported Nucleoplasm
Mitotic spindle
Cytosol Expressed in all parathyroid gland: 60.7 -CX3CL1 ABCD-3, C3Xkine, CXC3, CXC3C, fractalkine, neurotactin, NTN, SCYD1 ENSG00000006210 Chemokine (C-X3-C motif) ligand 1 16 57372458-57385048 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026192, HPA040361 Approved Supported Plasma membrane Tissue enhanced 0 cerebral cortex: 100.4 lung: 69.4 -SPATA20 FLJ21347, SSP411, Tisp78 ENSG00000006282 Spermatogenesis associated 20 17 50543058-50555852 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA022023, HPA027144, HPA031442 Approved Approved Nucleoplasm Expressed in all testis: 97.7 -CACNA1G Cav3.1, NBR13 ENSG00000006283 Calcium channel, voltage-dependent, T type, alpha 1G subunit 17 50561068-50627474 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA004714 Uncertain Tissue enhanced 0 cerebral cortex: 10.6;cervix, uterine: 8.5 endometrium: 5.2 -TNFRSF12A CD266, FN14, TweakR ENSG00000006327 Tumor necrosis factor receptor superfamily, member 12A 16 3018445-3022383 Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007853 Approved Approved Plasma membrane
Cytosol Expressed in all parathyroid gland: 195.6 -DLX6 ENSG00000006377 Distal-less homeobox 6 7 97005548-97011039 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030608, HPA061460 Uncertain Approved Nuclear bodies Tissue enhanced 0 endometrium: 4.4;placenta: 4.3;testis: 5.4 cervix: 3.0 -MAP3K9 MEKK9, MLK1, PRKE1 ENSG00000006432 Mitogen-activated protein kinase kinase kinase 9 14 70722526-70809534 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000942 Approved Approved Nucleus
Nucleoli Mixed testis: 10.1 -RALA RAL ENSG00000006451 V-ral simian leukemia viral oncogene homolog A (ras related) 7 39623483-39708124 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064515, HPA065232 Approved Supported Plasma membrane Expressed in all lung: 60.5 -BAIAP2L1 IRTKS ENSG00000006453 BAI1-associated protein 2-like 1 7 98291651-98401068 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019484, HPA021257, HPA023874, HPA029503 Supported Validated Plasma membrane
Cytosol Mixed stomach: 55.7 -KDM7A JHDM1D, KIAA1718 ENSG00000006459 Lysine (K)-specific demethylase 7A 7 140084746-140177035 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012114 Uncertain Supported Nucleoplasm
Nucleoli Mixed cervix: 14.2 -ETV1 ER81 ENSG00000006468 Ets variant 1 7 13891228-13991425 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA077249 Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 106.6 lung: 43.3 -AGK FLJ10842, MULK ENSG00000006530 Acylglycerol kinase 7 141551189-141655244 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020959, HPA053471 Supported Supported Vesicles
Mitochondria Expressed in all parathyroid gland: 24.8 -ALDH3B1 ALDH7 ENSG00000006534 Aldehyde dehydrogenase 3 family, member B1 11 68008578-68029282 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038525 Uncertain Tissue enhanced 0 fallopian tube: 63.7;lung: 67.9 bone marrow: 30.8 -TTC22 FLJ20619 ENSG00000006555 Tetratricopeptide repeat domain 22 1 54779712-54801267 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035072 Uncertain Tissue enhanced 0 esophagus: 40.8 skin: 22.8 -PHTF2 DKFZp434D166 ENSG00000006576 Putative homeodomain transcription factor 2 7 77798792-77957503 Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012312 Uncertain Approved Nucleoplasm
Cytosol Mixed parathyroid gland: 60.8 -CCL26 eotaxin-3, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1 ENSG00000006606 Chemokine (C-C motif) ligand 26 7 75769533-75789896 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 ovary: 11.9 rectum: 7.7 -FARP2 FIR, FRG, KIAA0793, PLEKHC3 ENSG00000006607 FERM, RhoGEF and pleckstrin domain protein 2 2 241356243-241494841 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031226, HPA055592 Approved Approved Cytosol Expressed in all testis: 37.3 -USH1C AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C ENSG00000006611 Usher syndrome 1C 11 17493895-17544416 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013690, HPA027398, HPA027492, HPA028033 Supported Validated Cytosol Tissue enhanced 0 duodenum: 101.9;small intestine: 109.0 kidney: 55.1 -GGCT C7orf24, CRF21, GCTG, Ggc, MGC3077 ENSG00000006625 Gamma-glutamylcyclotransferase 7 30496621-30504844 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020735, HPA029914 Approved Expressed in all epididymis: 123.9 -DBF4 ASK, chif, DBF4A, ZDBF1 ENSG00000006634 DBF4 zinc finger 7 87876216-87909541 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042923 Approved Nucleus Tissue enriched 40 testis: 21.3 epididymis: 0.5 -TBXA2R ENSG00000006638 Thromboxane A2 receptor 19 3594506-3606840 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA077366 Supported Nuclear speckles
Plasma membrane Mixed spleen: 5.3 -IFRD1 PC4, TIS7 ENSG00000006652 Interferon-related developmental regulator 1 7 112422968-112481017 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024122 Approved Approved Plasma membrane
Cytosol Expressed in all bone marrow: 130.1 -LGALS14 CLC2, PPL13 ENSG00000006659 Lectin, galactoside-binding, soluble, 14 19 39704306-39709444 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 57 placenta: 69.0 skin: 1.2 -COX10 ENSG00000006695 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 17 14069496-14208677 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032005, HPA032006 Supported Supported Nucleoli
Mitochondria
Cytosol Expressed in all testis: 43.0 -GTF2IRD1 BEN, Cream1, GTF3, MusTRD1, RBAP2, WBSCR11, WBSCR12 ENSG00000006704 GTF2I repeat domain containing 1 7 74453790-74602604 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044254 Approved Supported Nucleoplasm
Cytosol Mixed parathyroid gland: 34.7 -PAF1 F23149_1, FLJ11123, PD2 ENSG00000006712 PAF1 homolog, Paf1/RNA polymerase II complex component 19 39385852-39391195 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041875, HPA043637 Approved Supported Nucleoplasm Expressed in all testis: 87.0 -VPS41 HVSP41 ENSG00000006715 Vacuolar protein sorting 41 homolog (S. cerevisiae) 7 38722963-38932394 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020080, HPA020299 Approved Expressed in all cerebral cortex: 97.0 -ARHGAP44 KIAA0672, RICH-2, RICH2 ENSG00000006740 Rho GTPase activating protein 44 17 12789539-12991643 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038814 Uncertain Tissue enhanced 0 parathyroid gland: 50.8 cerebral cortex: 33.5 -ELAC2 FLJ10530, HPC2 ENSG00000006744 ElaC ribonuclease Z 2 17 12992391-13018187 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019535 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 53.9 -SCIN KIAA1905 ENSG00000006747 Scinderin 7 12570577-12660179 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020518, HPA024264 Supported Approved Plasma membrane
Cytosol Tissue enhanced 0 placenta: 116.3 small intestine: 52.7 -ARSD ENSG00000006756 Arylsulfatase D X 2903970-2929351 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004694, HPA063835 Supported Approved Vesicles
Lipid droplets Mixed fallopian tube: 44.7 -PNPLA4 DXS1283E, GS2, iPLA2eta ENSG00000006757 Patatin-like phospholipase domain containing 4 X 7898247-7927739 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003656 Approved Expressed in all thyroid gland: 50.3 -MYH13 MyHC-eo ENSG00000006788 Myosin, heavy chain 13, skeletal muscle 17 10298084-10373130 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Not detected placenta: 0.7 -ADIPOR2 ACDCR2, PAQR2 ENSG00000006831 Adiponectin receptor 2 12 1688574-1788678 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043737 Approved Expressed in all adipose tissue: 76.9 -CDKL3 NKIAMRE ENSG00000006837 Cyclin-dependent kinase-like 3 5 134286350-134371047 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027751 Uncertain Nucleoplasm
Vesicles Tissue enriched 9 testis: 28.7 cerebral cortex: 3.2 -UPP2 UDRPASE2, UP2, UPASE2 ENSG00000007001 Uridine phosphorylase 2 2 157876702-158136154 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035225, HPA035226 Approved Nucleus
Vesicles
Mitochondria Group enriched 14 kidney: 51.8;liver: 14.4 cerebral cortex: 2.4 -PRSS21 ESP-1, TEST1, TESTISIN ENSG00000007038 Protease, serine, 21 (testisin) 16 2817180-2826304 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008477 Supported Approved Cytosol Tissue enriched 10 testis: 49.3 bone marrow: 4.7 -MARK4 FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D ENSG00000007047 MAP/microtubule affinity-regulating kinase 4 19 45079288-45305283 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039186 Approved Approved Cytosol Expressed in all testis: 51.2 -PROM1 AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4 ENSG00000007062 Prominin 1 4 15963076-16084378 CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004922, CAB011525, HPA031053 Approved Tissue enhanced 0 cervix, uterine: 66.8 gallbladder: 47.7 -CCDC124 ENSG00000007080 Coiled-coil domain containing 124 19 17933016-17943991 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041708, HPA046765 Supported Validated Plasma membrane
Cytosol Expressed in all cerebral cortex: 72.6 -CEACAM21 FLJ13540, R29124_1 ENSG00000007129 Carcinoembryonic antigen-related cell adhesion molecule 21 19 41549518-41586844 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043411 Uncertain Tissue enhanced 0 bone marrow: 11.0 spleen: 6.6 -PAFAH1B1 LIS1, MDCR, MDS, PAFAH ENSG00000007168 Platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 17 2593210-2685615 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004489, HPA020036 Approved Validated Centrosome Expressed in all cerebral cortex: 179.2 -NOS2 HEP-NOS, iNOS, NOS, NOS2A ENSG00000007171 Nitric oxide synthase 2, inducible 17 27756766-27800499 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002014 Approved Group enriched 5 appendix: 19.6;colon: 7.2;duodenum: 12.6;rectum: 10.0;small intestine: 24.6;urinary bladder: 6.7 smooth muscle: 2.5 -DNAH9 DNAH17L, Dnahc9, DNAL1, DYH9, HL-20, HL20, KIAA0357 ENSG00000007174 Dynein, axonemal, heavy chain 9 17 11598431-11969748 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052641 Supported Tissue enriched 5 fallopian tube: 55.6 testis: 11.1 -KIAA0100 BCOX, BCOX1, CT101, DKFZp686M0843, MGC111488 ENSG00000007202 KIAA0100 17 28614440-28645454 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042781 Uncertain Approved Nuclear speckles
Cytosol Expressed in all parathyroid gland: 90.6 -SLC13A2 NaDC-1 ENSG00000007216 Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 17 28473293-28497781 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014963 Supported Tissue enhanced 0 duodenum: 70.6;small intestine: 55.4 kidney: 19.6 -GAS7 KIAA0394, MGC1348 ENSG00000007237 Growth arrest-specific 7 17 9910609-10198551 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004838, HPA064678 Supported Approved Plasma membrane
Actin filaments
Focal adhesion sites Tissue enhanced 0 cerebral cortex: 155.2 cervix: 47.5 -TRAPPC6A HSPC289, MGC2650, TRS33 ENSG00000007255 Trafficking protein particle complex 6A 19 45162928-45178237 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043043 Approved Expressed in all thyroid gland: 47.4 -MATK CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101 ENSG00000007264 Megakaryocyte-associated tyrosine kinase 19 3777970-3802129 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004847 Approved Tissue enhanced 0 cerebral cortex: 22.1 spleen: 20.2 -CEACAM7 CEA, CGM2 ENSG00000007306 Carcinoembryonic antigen-related cell adhesion molecule 7 19 41673307-41706976 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069621 Supported Group enriched 7 colon: 592.8;rectum: 701.8 appendix: 95.9 -CD79B B29, IGB ENSG00000007312 CD79b molecule, immunoglobulin-associated beta 17 63928740-63932354 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009178, CAB009751 Approved Uncertain Nucleoplasm
Plasma membrane
Cytosol Group enriched 5 appendix: 94.7;lymph node: 315.6;spleen: 160.3;tonsil: 196.1 bone marrow: 36.2 -SCN4A HYKPP, HYPP, Nav1.4, SkM1 ENSG00000007314 Sodium channel, voltage gated, type IV alpha subunit 17 63938554-63972918 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053992 Approved Nucleoplasm
Microtubule organizing center Group enriched 9 adipose tissue: 12.3;skeletal muscle: 47.2 thyroid gland: 3.3 -ST7L FAM4B, FLJ20284, ST7R, STLR ENSG00000007341 Suppression of tumorigenicity 7 like 1 112523518-112620825 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042324, HPA075418 Uncertain Approved Centrosome Tissue enriched 5 testis: 64.6 thyroid gland: 12.3 -TKTL1 TKR, TKT2 ENSG00000007350 Transketolase-like 1 X 154295671-154330350 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000505, CAB032191 Supported Tissue enriched 141 testis: 225.1 lung: 1.5 -PAX6 AN, AN2, D11S812E, WAGR ENSG00000007372 Paired box 6 11 31784792-31817961 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030775, CAB034143 Supported Validated Nucleoplasm Group enriched 6 cerebral cortex: 24.4;stomach: 12.1 testis: 2.9 -RPUSD1 C16orf40, MGC19600, RLUCL ENSG00000007376 RNA pseudouridylate synthase domain containing 1 16 784974-788397 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041144, HPA041938 Approved Approved Nucleus
Golgi apparatus
Cell Junctions
Cytosol Expressed in all appendix: 13.4 -RHBDF1 C16orf8, Dist1, EGFR-RS, FLJ2235, iRhom1 ENSG00000007384 Rhomboid 5 homolog 1 (Drosophila) 16 58059-76355 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077399 Uncertain Vesicles Mixed placenta: 39.6 -LUC7L hLuc7B1, Luc7, LUC7B1 ENSG00000007392 LUC7-like 16 188969-229463 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056424, HPA069321 Supported Approved Nucleus
Mitochondria Expressed in all testis: 41.2 -CACNA2D2 KIAA0558 ENSG00000007402 Calcium channel, voltage-dependent, alpha 2/delta subunit 2 3 50362799-50504244 FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034771, HPA071829 Approved Approved Vesicles Tissue enriched 6 lung: 73.0 testis: 12.4 -BAIAP3 BAP3, KIAA0734 ENSG00000007516 BAI1-associated protein 3 16 1333601-1349441 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015627 Uncertain Tissue enhanced 0 adrenal gland: 25.1;cerebral cortex: 25.2;fallopian tube: 41.9 testis: 13.8 -TSR3 C16orf42, MGC24381 ENSG00000007520 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 16 1349240-1351911 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040760, HPA046265 Uncertain Approved Golgi apparatus
Cytosol Expressed in all cerebral cortex: 36.8 -PIGQ GPI1, hGPI1 ENSG00000007541 Phosphatidylinositol glycan anchor biosynthesis, class Q 16 566995-584136 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039105, HPA039828, HPA061414 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all bone marrow: 24.2 -CRAMP1 CRAMP1L, KIAA1426 ENSG00000007545 Cramped chromatin regulator homolog 1 16 1612325-1677908 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041752 Uncertain Approved Nucleus
Nucleoli
Cytosol Mixed testis: 31.8 -TEAD3 ETFR-1, TEAD5, TEF-5 ENSG00000007866 TEA domain family member 3 6 35473597-35497076 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028906 Uncertain Mixed smooth muscle: 75.1 -SELE CD62E, ELAM, ELAM1, ESEL ENSG00000007908 Selectin E 1 169722641-169764705 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002143 Supported Tissue enhanced 0 parathyroid gland: 44.4;prostate: 40.0 urinary bladder: 28.6 -DNAJC11 FLJ10737 ENSG00000007923 DnaJ (Hsp40) homolog, subfamily C, member 11 1 6634168-6701924 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028705 Uncertain Approved Cytosol Expressed in all kidney: 38.2 -FMO3 ENSG00000007933 Flavin containing monooxygenase 3 1 171090877-171117819 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013750 Supported Tissue enriched 25 liver: 555.8 fallopian tube: 22.5 -MYLIP IDOL, MIR ENSG00000007944 Myosin regulatory light chain interacting protein 6 16129125-16148248 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all placenta: 118.5 -NOX1 GP91-2, MOX1, NOH-1, NOH1 ENSG00000007952 NADPH oxidase 1 X 100843324-100874345 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 17 colon: 60.0;rectum: 81.1 appendix: 4.0 -E2F2 E2F-2 ENSG00000007968 E2F transcription factor 2 1 23506430-23531220 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level CAB016313 Uncertain Tissue enhanced 0 bone marrow: 15.3 lymph node: 3.9 -PSMB1 HC5, PMSB1 ENSG00000008018 Proteasome subunit beta 1 6 170535117-170553341 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029635, HPA029637, CAB033911 Supported Supported Nucleus Expressed in all epididymis: 314.7 -SYN1 ENSG00000008056 Synapsin I X 47571898-47619853 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000397, CAB021929 Supported Tissue enriched 31 cerebral cortex: 236.8 adrenal gland: 7.7 -JARID2 JMJ ENSG00000008083 Jumonji, AT rich interactive domain 2 6 15246296-15522040 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063889, CAB069890 Uncertain Supported Nucleus
Mitochondria Mixed bone marrow: 36.6 -CDKL5 CFAP247, EIEE2, STK9 ENSG00000008086 Cyclin-dependent kinase-like 5 X 18425583-18653629 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002847, CAB011577 Supported Validated Nucleoplasm Tissue enhanced 0 cerebral cortex: 31.2 testis: 14.6 -CAMK1G CLICKIII, dJ272L16.1, VWS1 ENSG00000008118 Calcium/calmodulin-dependent protein kinase IG 1 209583717-209613938 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 32.4;ovary: 27.7 seminal vesicle: 7.3 -CDK11A CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE ENSG00000008128 Cyclin-dependent kinase 11A 1 1702730-1724324 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010467, HPA025061, HPA073626 Supported Supported Nuclear speckles
Cytosol Expressed in all small intestine: 35.8 -NADK FLJ13052 ENSG00000008130 NAD kinase 1 1751232-1780457 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048909, HPA053368 Uncertain Approved Nucleoplasm
Vesicles Expressed in all spleen: 78.8 -TFAP2B AP2-B ENSG00000008196 Transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6 50818723-50847613 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA034683, HPA062942 Approved Approved Nucleoplasm Tissue enhanced 0 epididymis: 38.7 breast: 9.5 -TFAP2D TFAP2BL1 ENSG00000008197 Transcription factor AP-2 delta (activating enhancer binding protein 2 delta) 6 50713828-50772988 Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at transcript level Evidence at protein level HPA048962 Uncertain Not detected testis: 0.1 -DLEC1 CFAP81, DLC1 ENSG00000008226 Deleted in lung and esophageal cancer 1 3 38039205-38124025 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019077 Supported Supported Cytosol Tissue enhanced 0 fallopian tube: 29.4;testis: 17.3 lung: 6.0 -CYTH3 ARNO3, cytohesin-3, GRP1, PSCD3 ENSG00000008256 Cytohesin 3 7 6161776-6272644 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013979 Uncertain Supported Nucleoplasm
Cytosol Expressed in all placenta: 45.2 -ADAM22 MDC2 ENSG00000008277 ADAM metallopeptidase domain 22 7 87934143-88202889 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050325 Approved Cell Junctions Tissue enhanced 0 cerebral cortex: 47.7 prostate: 17.5 -SYPL1 SYPL ENSG00000008282 Synaptophysin-like 1 7 106090503-106112576 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014141 Approved Expressed in all thyroid gland: 194.0 -CYB561 CYB561A1, FRRS2 ENSG00000008283 Cytochrome b561 17 63432304-63446378 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014753 Approved Expressed in all adrenal gland: 164.3 -SPAG9 CT89, FLJ13450, FLJ14006, FLJ26141, FLJ34602, HLC4, HSS, JLP, KIAA0516, MGC117291, MGC14967, MGC74461, PHET, PIG6, SYD1 ENSG00000008294 Sperm associated antigen 9 17 50962174-51120865 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040446, HPA061458 Approved Validated Microtubule organizing center
Cytosol Expressed in all cerebral cortex: 106.4 -CELSR3 ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2 ENSG00000008300 Cadherin, EGF LAG seven-pass G-type receptor 3 3 48636469-48662915 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062866 Approved Group enriched 6 adrenal gland: 1.6;cerebral cortex: 6.0;testis: 3.6 parathyroid gland: 0.6 -AASS LKRSDH, LORSDH ENSG00000008311 Aminoadipate-semialdehyde synthase 7 122075647-122144280 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020637, HPA020728, HPA020734 Supported Validated Vesicles
Mitochondria Mixed ovary: 30.6 -PLEKHG6 FLJ10665, MYOGEF ENSG00000008323 Pleckstrin homology domain containing, family G (with RhoGef domain) member 6 12 6310436-6328506 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041459, HPA058230 Uncertain Validated Plasma membrane Tissue enhanced 0 small intestine: 48.7 duodenum: 37.6 -SS18L2 KIAA-iso ENSG00000008324 Synovial sarcoma translocation gene on chromosome 18-like 2 3 42581840-42595114 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA047377 Uncertain Approved Nucleus
Nucleoli
Mitochondria Expressed in all lymph node: 58.8 -MPND FLJ14981 ENSG00000008382 MPN domain containing 19 4343527-4360086 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043274, HPA045475 Approved Approved Nucleus
Nucleoli Expressed in all duodenum: 31.8 -MGST1 GST12, MGST-I ENSG00000008394 Microsomal glutathione S-transferase 1 12 16347142-16609259 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044840 Supported Approved Endoplasmic reticulum
Mitochondria Expressed in all liver: 1596.8 -CRY1 PHLL1 ENSG00000008405 Cryptochrome circadian clock 1 12 106991364-107093829 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018762 Approved Supported Nucleus
Nuclear membrane
Microtubules Expressed in all testis: 61.9 -PGLYRP1 PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L ENSG00000008438 Peptidoglycan recognition protein 1 19 46019153-46023065 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045702 Supported Tissue enriched 55 bone marrow: 421.9 spleen: 7.6 -NFIX NF1A ENSG00000008441 Nuclear factor I/X (CCAAT-binding transcription factor) 19 12995608-13098796 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007533 Supported Supported Nucleoplasm Expressed in all cerebral cortex: 192.0 -ST3GAL1 SIAT4A, SIATFL, ST3GalA.1, ST3O ENSG00000008513 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 8 133454848-133571940 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040466 Approved Expressed in all thyroid gland: 115.4 -MMP25 MMP20, MMPL1, MT6-MMP ENSG00000008516 Matrix metallopeptidase 25 16 3046681-3060726 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB025177 Uncertain Tissue enhanced 0 appendix: 23.9;bone marrow: 24.7;spleen: 21.1 adipose tissue: 6.3 -IL32 NK4, TAIF, TAIFb, TAIFd ENSG00000008517 Interleukin 32 16 3065297-3082192 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029397, CAB030029 Approved Expressed in all small intestine: 632.5 -PKD1 PBP, Pc-1, TRPP1 ENSG00000008710 Polycystic kidney disease 1 (autosomal dominant) 16 2088710-2135898 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB046448 Approved Mixed cerebral cortex: 21.6 -MAPK8IP2 IB2, JIP2, PRKM8IPL ENSG00000008735 Mitogen-activated protein kinase 8 interacting protein 2 22 50600685-50613981 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034780 Uncertain Tissue enriched 8 cerebral cortex: 78.5 adrenal gland: 10.1 -MED24 CRSP100, CRSP4, DRIP100, KIAA0130, MED5, THRAP4, TRAP100 ENSG00000008838 Mediator complex subunit 24 17 40019097-40061215 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 64.2 -RHOBTB2 DBC2, KIAA0717 ENSG00000008853 Rho-related BTB domain containing 2 8 22987417-23020199 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060938 Approved Approved Plasma membrane Mixed lung: 53.1 -HEATR5B DKFZp686P15184, KIAA1414 ENSG00000008869 HEAT repeat containing 5B 2 36968383-37084342 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042025, HPA055639 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all lymph node: 38.4 -SEC62 Dtrp1, HTP1, TLOC1 ENSG00000008952 SEC62 homolog, preprotein translocation factor 3 169966635-169998373 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014059, HPA061450 Approved Approved Endoplasmic reticulum
Intermediate filaments Expressed in all thyroid gland: 202.4 -RPS20 S20 ENSG00000008988 Ribosomal protein S20 8 56067295-56074581 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003570 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all ovary: 4357.5 -CSDE1 D1S155E, UNR ENSG00000009307 Cold shock domain containing E1, RNA-binding 1 114716913-114758676 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018846, HPA052221 Supported Validated Cytosol Expressed in all skeletal muscle: 490.4 -UBE3C KIAA0010, KIAA10 ENSG00000009335 Ubiquitin protein ligase E3C 7 157138913-157269372 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039915 Approved Approved Nucleoplasm
Plasma membrane
Mitochondria Expressed in all parathyroid gland: 50.2 -REV3L POLZ, REV3 ENSG00000009413 REV3-like, polymerase (DNA directed), zeta, catalytic subunit 6 111299028-111483715 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064853, HPA069382 Uncertain Approved Nucleoplasm Expressed in all cervix: 44.3 -TENM1 ODZ1, ODZ3, TEN-M1, TNM ENSG00000009694 Teneurin transmembrane protein 1 X 124375903-124963817 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002848 Uncertain Mixed cerebral cortex: 3.8 -PAX7 Hup1 ENSG00000009709 Paired box 7 1 18631006-18748866 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 7 cerebral cortex: 1.4;skeletal muscle: 2.2 testis: 0.2 -MASP2 MASP1P1 ENSG00000009724 Mannan-binding lectin serine peptidase 2 1 11026523-11047233 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029313, HPA029314 Approved Supported Golgi apparatus Tissue enriched 18 liver: 105.4 skin: 5.7 -IYD C6orf71, DEHAL1, dJ422F24.1 ENSG00000009765 Iodotyrosine deiodinase 6 150368892-150405969 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059627 Supported Supported Plasma membrane Tissue enriched 28 thyroid gland: 792.4 kidney: 27.9 -FAM76A MGC34648 ENSG00000009780 Family with sequence similarity 76, member A 1 27725979-27763122 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044762, HPA077897 Uncertain Approved Nucleus
Cytosol Expressed in all testis: 32.4 -TRAF3IP3 T3JAM ENSG00000009790 TRAF3 interacting protein 3 1 209756032-209782320 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040796 Approved Approved Vesicles Tissue enhanced 0 lymph node: 116.4;spleen: 83.8;tonsil: 86.0 appendix: 70.3 -POMT2 LGMD2N ENSG00000009830 Protein-O-mannosyltransferase 2 14 77274956-77320884 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003663 Uncertain Expressed in all testis: 28.8 -VTA1 C6orf55, HSPC228, My012 ENSG00000009844 Vesicle (multivesicular body) trafficking 1 6 142147162-142224689 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030968, HPA030969 Approved Supported Nucleoplasm
Vesicles
Cytosol Expressed in all cerebral cortex: 61.1 -MLXIPL bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH ENSG00000009950 MLX interacting protein-like 7 73593194-73624543 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064640 Supported Nucleus Tissue enhanced 0 adipose tissue: 60.8;duodenum: 60.3 liver: 47.2 -BAZ1B WBSCR10, WBSCR9, WSTF ENSG00000009954 Bromodomain adjacent to zinc finger domain, 1B 7 73440398-73522278 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037081, CAB037158, HPA067010 Supported Supported Nuclear bodies Expressed in all parathyroid gland: 53.9 -RANBP9 RanBPM ENSG00000010017 RAN binding protein 9 6 13621498-13711564 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033767, HPA050007 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 210.7 -ETV7 TEL-2, TEL2 ENSG00000010030 Ets variant 7 6 36354091-36387800 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA029033 Uncertain Supported Nucleoplasm Mixed skin: 19.9 -SPRTN C1orf124, DKFZP547N043, DVC1, Spartan ENSG00000010072 SprT-like N-terminal domain 1 231337104-231355023 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA025073 Uncertain Supported Nucleoplasm Mixed testis: 24.9 -METTL13 CGI-01, KIAA0859 ENSG00000010165 Methyltransferase like 13 1 171781664-171814023 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044498, HPA053705 Approved Approved Cytosol Expressed in all testis: 24.7 -DYRK4 ENSG00000010219 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 12 4562204-4615302 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028065, HPA056073 Uncertain Validated Vesicles Tissue enhanced 0 testis: 65.8 epididymis: 20.3 -ZNF207 ENSG00000010244 Zinc finger protein 207 17 32350117-32381886 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017013, HPA063908 Supported Validated Nucleus Expressed in all bone marrow: 151.6 -UQCRC1 D3S3191, QCR1, UQCR1 ENSG00000010256 Ubiquinol-cytochrome c reductase core protein I 3 48599002-48610976 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002815, HPA003525, CAB033782 Supported Supported Mitochondria
Cytosol Expressed in all skeletal muscle: 88.3 -STARD3NL MENTHO, MGC3251 ENSG00000010270 STARD3 N-terminal like 7 38178222-38230671 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019204 Supported Supported Vesicles Expressed in all placenta: 69.9 -CD9 BA2, MIC3, MRP-1, P24, TSPAN29 ENSG00000010278 CD9 molecule 12 6199715-6238271 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002490 Supported Supported Plasma membrane Expressed in all esophagus: 1009.8 -HHATL C3orf3, GUP1, KIAA1173, MBOAT3, MSTP002, OACT3 ENSG00000010282 Hedgehog acyltransferase-like 3 42692663-42702827 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA018174 Supported Tissue enhanced 0 heart muscle: 333.2;skeletal muscle: 97.6 cerebral cortex: 53.4 -NCAPD2 CAP-D2, CNAP1, hCAP-D2, KIAA0159 ENSG00000010292 Non-SMC condensin I complex, subunit D2 12 6493356-6531955 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012423, HPA036947, HPA037363 Supported Supported Nucleus
Cytosol Expressed in all lymph node: 29.1 -IFFO1 HOM-TES-103, IFFO ENSG00000010295 Intermediate filament family orphan 1 12 6538375-6556083 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA069344 Approved Mixed spleen: 12.2 -GIPR ENSG00000010310 Gastric inhibitory polypeptide receptor 19 45668244-45683724 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022710 Uncertain Tissue enhanced 0 stomach: 22.6 parathyroid gland: 12.2 -PHF7 HSPC226, NYD-SP6 ENSG00000010318 PHD finger protein 7 3 52410561-52423641 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA036283, HPA070305 Supported Supported Nucleoplasm
Golgi apparatus Tissue enriched 422 testis: 2170.2 rectum: 5.1 -SEMA3G FLJ00014, sem2 ENSG00000010319 Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 3 52433053-52445085 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA001761 Uncertain Tissue enhanced 0 adipose tissue: 82.0 placenta: 42.0 -NISCH I-1, IRAS, KIAA0975 ENSG00000010322 Nischarin 3 52455118-52493071 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023189 Approved Expressed in all testis: 96.0 -STAB1 CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, STAB-1 ENSG00000010327 Stabilin 1 3 52495338-52524495 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005434 Approved Expressed in all spleen: 125.2 -FUZ FLJ22688, Fy ENSG00000010361 Fuzzy planar cell polarity protein 19 49806869-49817376 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA041779, HPA042196 Uncertain Approved Cytosol Expressed in all testis: 52.6 -SLC6A13 GAT2 ENSG00000010379 Solute carrier family 6 (neurotransmitter transporter), member 13 12 220621-262873 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036449, HPA052726 Approved Approved Mitochondria Tissue enriched 14 kidney: 152.9 fallopian tube: 11.2 -IDS SIDS ENSG00000010404 Iduronate 2-sulfatase X 149476990-149521096 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 437.1 -PRSS3 PRSS4, TRY3, TRY4 ENSG00000010438 Protease, serine, 3 9 33750466-33799231 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062452, HPA063471 Supported Approved Endoplasmic reticulum
Vesicles Tissue enriched 62 pancreas: 6299.8 small intestine: 101.1 -ZNF200 ENSG00000010539 Zinc finger protein 200 16 3222325-3236221 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA018981, HPA059310 Uncertain Approved Mitochondria Tissue enhanced 0 testis: 31.5 placenta: 8.7 -CD4 ENSG00000010610 CD4 molecule 12 6786858-6820808 CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000011, HPA004252, HPA004472, CAB068180 Supported Supported Plasma membrane Tissue enhanced 0 parathyroid gland: 538.7 spleen: 224.0 -LRRC23 B7, LRPB7 ENSG00000010626 Leucine rich repeat containing 23 12 6873569-6914243 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037766, HPA057533 Supported Supported Nucleoli Group enriched 7 fallopian tube: 164.7;testis: 43.2 epididymis: 14.9 -BTK AGMX1, ATK, IMD1, PSCTK1, XLA ENSG00000010671 Bruton agammaglobulinemia tyrosine kinase X 101349447-101390796 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001198, HPA002028, CAB016689 Supported Supported Vesicles Tissue enhanced 0 lymph node: 66.0;tonsil: 73.6 spleen: 53.6 -HFE HLA-H ENSG00000010704 Hemochromatosis 6 26087281-26098343 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017276, HPA053470 Approved Approved Nuclear membrane
Mitochondria Mixed parathyroid gland: 27.3 -SCMH1 Scml3 ENSG00000010803 Sex comb on midleg homolog 1 (Drosophila) 1 41027200-41242154 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048898, HPA053292 Supported Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 55.0 -FYN MGC45350, SLK, SYN ENSG00000010810 FYN proto-oncogene, Src family tyrosine kinase 6 111660332-111873452 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005034, CAB018387, HPA023887, HPA063770 Approved Validated Plasma membrane
Cytosol Expressed in all cerebral cortex: 166.6 -HIVEP2 HIV-EP2, MBP-2, MIBP1, Schnurri-2, ZAS2, ZNF40B ENSG00000010818 Human immunodeficiency virus type I enhancer binding protein 2 6 142751467-142945201 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055954 Supported Nucleoplasm Expressed in all cerebral cortex: 31.5 -FMO1 ENSG00000010932 Flavin containing monooxygenase 1 1 171248471-171285978 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023680 Uncertain Tissue enriched 8 kidney: 218.3 small intestine: 25.7 -TCEB3 SIII, TCEB3A ENSG00000011007 Transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 1 23743155-23762059 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005910 Approved Approved Nuclear speckles
Cytosol Expressed in all lung: 38.6 -LYPLA2 APT-2 ENSG00000011009 Lysophospholipase II 1 23790970-23795539 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063151 Uncertain Nucleoplasm
Cytosol Expressed in all parathyroid gland: 107.0 -CLCN6 CLC-6, KIAA0046 ENSG00000011021 Chloride channel, voltage-sensitive 6 1 11806096-11843144 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032097 Approved Approved Plasma membrane
Cytosol Mixed cerebral cortex: 31.2 -MRC2 CD280, CLEC13E, ENDO180, KIAA0709 ENSG00000011028 Mannose receptor, C type 2 17 62627401-62693597 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041991 Supported Expressed in all gallbladder: 39.9 -NME1-NME2 NM23-LV, NMELV ENSG00000011052 NME1-NME2 readthrough 17 51153590-51171744 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB002169, HPA008467, HPA041113 Approved Supported Cytosol Expressed in all appendix: 50.0 -SLC6A7 PROT ENSG00000011083 Solute carrier family 6 (neurotransmitter transporter), member 7 5 150189957-150222788 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA028907 Uncertain Tissue enhanced 0 cerebral cortex: 17.0;rectum: 4.3 colon: 2.9 -TSPAN9 NET-5 ENSG00000011105 Tetraspanin 9 12 3077355-3286564 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014002 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Mixed heart muscle: 81.6 -BTBD7 FLJ10648, FUP1 ENSG00000011114 BTB (POZ) domain containing 7 14 93237550-93333092 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049926, HPA053406 Uncertain Approved Focal adhesion sites Mixed parathyroid gland: 18.3 -APBA3 mint3, X11L2 ENSG00000011132 Amyloid beta (A4) precursor protein-binding, family A, member 3 19 3750819-3761699 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045577 Approved Approved Vesicles Mixed spleen: 6.8 -MKS1 BBS13, FLJ20345, MKS, POC12 ENSG00000011143 Meckel syndrome, type 1 17 58205437-58219605 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021372, HPA021812 Approved Expressed in all fallopian tube: 32.0 -ABHD5 CGI-58, NCIE2 ENSG00000011198 Abhydrolase domain containing 5 3 43690113-43734371 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020685, HPA035851, HPA035852 Approved Approved Vesicles Expressed in all adipose tissue: 50.3 -ANOS1 ADMLX, KAL, KAL1, KALIG-1, WFDC19 ENSG00000011201 Anosmin 1 X 8528874-8732187 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 cerebral cortex: 32.5;lung: 66.1;parathyroid gland: 47.6;thyroid gland: 15.7 testis: 7.4 -AKAP8L HAP95, NAKAP95 ENSG00000011243 A kinase (PRKA) anchor protein 8-like 19 15380048-15419141 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042485, HPA042546 Supported Supported Nuclear speckles Expressed in all testis: 41.5 -MBTD1 FLJ20055, SA49P01 ENSG00000011258 Mbt domain containing 1 17 51177425-51260163 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021876 Approved Approved Nucleus
Cytosol Expressed in all testis: 45.9 -UTP18 CGI-48, WDR50 ENSG00000011260 UTP18 small subunit (SSU) processome component 17 51260528-51297936 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052378 Approved Supported Nucleus
Nuclear membrane
Nucleoli Expressed in all testis: 105.6 -RNF216 TRIAD3, UBCE7IP1, ZIN ENSG00000011275 Ring finger protein 216 7 5620047-5781739 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018955, HPA021123 Supported Supported Nucleoplasm
Cytosol Expressed in all testis: 49.9 -TTC19 FLJ20343, MGC19520 ENSG00000011295 Tetratricopeptide repeat domain 19 17 15999380-16045015 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023010, HPA052380 Approved Validated Mitochondria Expressed in all thyroid gland: 18.8 -PTBP1 HNRNP-I, HNRPI, pPTB, PTB, PTB-1, PTB2, PTB3, PTB4 ENSG00000011304 Polypyrimidine tract binding protein 1 19 797075-812327 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013507 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 169.8 -DPF1 BAF45b, NEUD4, neuro-d4 ENSG00000011332 D4, zinc and double PHD fingers family 1 19 38211006-38229714 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049148 Supported Approved Nucleoplasm
Mitochondria
Cytosol Tissue enriched 15 cerebral cortex: 27.5 testis: 1.8 -SYT7 IPCA-7, MGC150517, PCANAP7, SYT-VII ENSG00000011347 Synaptotagmin VII 11 61515313-61581148 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012869 Supported Tissue enhanced 0 cerebral cortex: 109.0;prostate: 79.3 placenta: 26.5 -LARS2 KIAA0028, LEURS, MGC26121 ENSG00000011376 Leucyl-tRNA synthetase 2, mitochondrial 3 45388506-45549421 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035951, HPA045450, HPA066085 Approved Supported Nucleoplasm
Mitochondria Expressed in all parathyroid gland: 18.9 -PIK3C2A PI3K-C2alpha ENSG00000011405 Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 11 17077730-17207983 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037641, HPA037642 Uncertain Supported Nucleus Expressed in all parathyroid gland: 92.8 -PLAUR CD87, UPAR, URKR ENSG00000011422 Plasminogen activator, urokinase receptor 19 43646095-43670547 Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050843, CAB073533 Uncertain Supported Plasma membrane Expressed in all bone marrow: 429.4 -ANLN ANILLIN, scra, Scraps ENSG00000011426 Anillin actin binding protein 7 36389806-36453791 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005680, CAB033902, HPA050556, CAB062547, CAB068175 Supported Supported Nucleoplasm Tissue enhanced 0 cerebral cortex: 87.4 bone marrow: 23.2 -WIZ ZNF803 ENSG00000011451 Widely interspaced zinc finger motifs 19 15419980-15449951 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022923, HPA023774 Supported Validated Nucleoplasm
Midbody Expressed in all testis: 31.0 -RABGAP1 GAPCenA, TBC1D11 ENSG00000011454 RAB GTPase activating protein 1 9 122940833-123104866 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041651, HPA064860, HPA072273 Approved Validated Cytosol Expressed in all thyroid gland: 66.1 -DCN DSPG2, SLRR1B ENSG00000011465 Decorin 12 91140484-91183123 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003315, CAB017118, HPA064736, CAB068930 Supported Expressed in all ovary: 3801.6 -QPCTL FLJ20084 ENSG00000011478 Glutaminyl-peptide cyclotransferase-like 19 45692483-45703989 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040797 Approved Supported Golgi apparatus Mixed thyroid gland: 8.6 -PPP5C PP5, PPP5 ENSG00000011485 Protein phosphatase 5, catalytic subunit 19 46346994-46392981 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022641, HPA029065, HPA056933 Approved Supported Vesicles
Cytosol Expressed in all cerebral cortex: 44.5 -CEP68 KIAA0582 ENSG00000011523 Centrosomal protein 68kDa 2 65056366-65087004 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040493, HPA040620 Approved Supported Nucleus
Microtubule organizing center Expressed in all cerebral cortex: 28.5 -MAP4K3 GLK, MAPKKKK3, RAB8IPL1 ENSG00000011566 Mitogen-activated protein kinase kinase kinase kinase 3 2 39249266-39437312 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030380 Approved Approved Centrosome Expressed in all thyroid gland: 40.7 -ZBTB32 FAXF, FAZF, Rog, TZFP, ZNF538 ENSG00000011590 Zinc finger and BTB domain containing 32 19 35704527-35717038 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 testis: 43.4 lymph node: 3.9 -TYROBP DAP12, KARAP, PLO-SL, PLOSL ENSG00000011600 TYRO protein tyrosine kinase binding protein 19 35904401-35908295 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009493, HPA041899 Supported Expressed in all bone marrow: 387.8 -TMEM159 promethin ENSG00000011638 Transmembrane protein 159 16 21158377-21180616 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018033, HPA063509 Approved Approved Vesicles Expressed in all skin: 90.6 -GABRA3 ENSG00000011677 Gamma-aminobutyric acid (GABA) A receptor, alpha 3 X 152166234-152451358 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000839 Approved Supported Tissue enriched 7 cerebral cortex: 28.9 placenta: 4.1 -BRCA1 BRCC1, FANCS, PPP1R53, RNF53 ENSG00000012048 Breast cancer 1, early onset 17 43044295-43170245 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001946, HPA034966 Approved Mixed testis: 23.9 -ERCC1 RAD10 ENSG00000012061 Excision repair cross-complementation group 1 19 45407333-45478828 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004390, HPA029773, HPA050182, CAB072859, CAB072860 Supported Validated Nucleoplasm Expressed in all skin: 71.4 -CD22 SIGLEC-2, SIGLEC2 ENSG00000012124 CD22 molecule 19 35319261-35347355 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002418, HPA024353 Supported Tissue enhanced 0 lymph node: 269.3;ovary: 163.3;spleen: 155.4;tonsil: 219.0 appendix: 102.4 -SEMA3B LUCA-1, SemA, sema5, SEMAA, semaV ENSG00000012171 Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 3 50267558-50277546 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed adrenal gland: 75.9 -MBTPS2 KFSD, S2P ENSG00000012174 Membrane-bound transcription factor peptidase, site 2 X 21839636-21885424 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA005494, CAB009486 Approved Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all parathyroid gland: 19.0 -PRICKLE3 LMO6 ENSG00000012211 Prickle homolog 3 X 49175264-49186528 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA000998, HPA001442 Uncertain Approved Nucleus
Plasma membrane
Centrosome Mixed skin: 11.7 -LTF HLF2 ENSG00000012223 Lactotransferrin 3 46435645-46485234 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008646, CAB016201, HPA057177, HPA059976 Supported Tissue enhanced 0 bone marrow: 2808.6;cervix, uterine: 1024.2 seminal vesicle: 526.7 -EXTL3 botv, REGR ENSG00000012232 Exostosin-like glycosyltransferase 3 8 28600469-28755599 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025387 Approved Expressed in all parathyroid gland: 36.0 -NR1H4 FXR, HRR-1, HRR1, RIP14 ENSG00000012504 Nuclear receptor subfamily 1, group H, member 4 12 100473708-100564413 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047699 Approved Nucleoplasm Tissue enhanced 0 liver: 66.4;small intestine: 45.2 duodenum: 30.7 -ELOVL5 dJ483K16.1, HELO1, SCA38 ENSG00000012660 ELOVL fatty acid elongase 5 6 53267398-53349179 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017042, HPA047752, HPA054197 Supported Validated Endoplasmic reticulum Expressed in all adipose tissue: 256.1 -ALOX5 5-LOX ENSG00000012779 Arachidonate 5-lipoxygenase 10 45374176-45446119 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071285 Supported Supported Nucleoplasm Tissue enhanced 0 lung: 41.4 bone marrow: 28.9 -KDM5D HY, HYA, JARID1D, KIAA0234, SMCY ENSG00000012817 Lysine (K)-specific demethylase 5D Y 19703865-19744939 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049086, HPA060807 Uncertain Approved Nucleoli fibrillar center Mixed small intestine: 37.3 -CALCOCO1 calphoglin, Cocoa, KIAA1536 ENSG00000012822 Calcium binding and coiled-coil domain 1 12 53708517-53727745 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038313, HPA038314 Approved Validated Cytosol Expressed in all skin: 161.0 -UBR7 C14orf130 ENSG00000012963 Ubiquitin protein ligase E3 component n-recognin 7 (putative) 14 93207056-93229215 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000861 Approved Approved Nucleus Expressed in all parathyroid gland: 22.8 -MAP4K5 GCKR, KHS, KHS1 ENSG00000012983 Mitogen-activated protein kinase kinase kinase kinase 5 14 50418501-50561126 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA036696 Uncertain Approved Plasma membrane
Cytosol Expressed in all endometrium: 54.9 -EHD3 PAST3 ENSG00000013016 EH-domain containing 3 2 31234337-31269447 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049890, HPA049986, HPA066751 Approved Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 83.0 esophagus: 33.5 -PSMC4 MGC13687, MGC23214, MGC8570, MIP224, S6, TBP-7, TBP7 ENSG00000013275 Proteasome 26S subunit, ATPase 4 19 39971005-39981441 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002044, HPA005471 Approved Supported Nucleus
Cytosol Expressed in all parathyroid gland: 42.3 -MAN2B2 KIAA0935 ENSG00000013288 Mannosidase, alpha, class 2B, member 2 4 6575175-6623362 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037005 Uncertain Expressed in all thyroid gland: 37.6 -SLC7A14 KIAA1613, PPP1R142 ENSG00000013293 Solute carrier family 7, member 14 3 170459584-170586074 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045929 Approved Tissue enriched 8 cerebral cortex: 26.8 adrenal gland: 3.1 -CLDN11 OSP, OTM ENSG00000013297 Claudin 11 3 170418865-170860380 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB009789, HPA013166 Supported Tissue enhanced 0 cerebral cortex: 89.2;testis: 184.3 ovary: 61.8 -SLC25A39 CGI-69, FLJ22407 ENSG00000013306 Solute carrier family 25, member 39 17 44319625-44324870 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026785 Approved Expressed in all bone marrow: 181.5 -MVP LRP, VAULT1 ENSG00000013364 Major vault protein 16 29820394-29848039 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002321, CAB002752, CAB022717, HPA064740 Supported Validated Cytosol Expressed in all small intestine: 169.1 -NUB1 BS4, NUB1L, NYREN18 ENSG00000013374 Negative regulator of ubiquitin-like proteins 1 7 151341699-151378449 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA021220, HPA050722, HPA053648 Approved Validated Nucleus
Nucleoli Expressed in all parathyroid gland: 106.8 -PGM3 AGM1, DKFZP434B187, PAGM ENSG00000013375 Phosphoglucomutase 3 6 83161150-83193936 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004998, HPA029759, HPA029760 Supported Approved Nucleoplasm
Cytosol Expressed in all prostate: 78.7 -RWDD2A dJ747H23.2, MGC13523, RWDD2 ENSG00000013392 RWD domain containing 2A 6 83193379-83198932 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030105, HPA030106, HPA030107 Uncertain Approved Vesicles Mixed prostate: 18.8 -CLK1 ENSG00000013441 CDC-like kinase 1 2 200853009-200864744 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033141, HPA062405 Approved Supported Nucleoplasm
Nuclear membrane Expressed in all bone marrow: 113.8 -POLR3B FLJ10388, RPC2 ENSG00000013503 Polymerase (RNA) III (DNA directed) polypeptide B 12 106357658-106510198 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036466 Supported Approved Nuclear speckles Mixed parathyroid gland: 23.8 -ANGEL1 Ccr4e, KIAA0759 ENSG00000013523 Angel homolog 1 (Drosophila) 14 76786178-76826246 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA000948 Uncertain Approved Nucleoplasm Expressed in all testis: 68.0 -RNF14 ARA54, HFB30, TRIAD2 ENSG00000013561 Ring finger protein 14 5 141958328-141990291 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008716 Approved Supported Cytosol Expressed in all testis: 136.4 -DNASE1L1 DNAS1L1, DNASEX, DNL1L, XIB ENSG00000013563 Deoxyribonuclease I-like 1 X 154401238-154412112 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072635 Approved Expressed in all skeletal muscle: 56.7 -DDX11 CHL1, CHLR1, KRG2, WABS ENSG00000013573 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 12 31073845-31104791 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065197 Supported Supported Nucleus
Nucleoli Expressed in all skin: 19.3 -HEBP1 HBP, HEBP ENSG00000013583 Heme binding protein 1 12 12974864-13000273 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056417, HPA075277 Approved Approved Nucleus
Vesicles Expressed in all duodenum: 241.2 -GPRC5A PEIG-1, RAI3, RAIG1, TIG1 ENSG00000013588 G protein-coupled receptor, class C, group 5, member A 12 12890782-12917937 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007928, HPA046526 Approved Validated Vesicles
Plasma membrane Tissue enhanced 0 lung: 302.3 thyroid gland: 90.7 -MAMLD1 CG1, CXorf6, F18 ENSG00000013619 Mastermind-like domain containing 1 X 150361422-150514178 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA003923 Uncertain Supported Nucleoplasm Tissue enhanced 0 testis: 18.7 ovary: 16.1 -CD6 Tp120 ENSG00000013725 CD6 molecule 11 60971680-61020377 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002489, CAB016252 Supported Tissue enhanced 0 appendix: 29.5;lymph node: 49.8 tonsil: 27.7 -TACC3 ERIC1 ENSG00000013810 Transforming, acidic coiled-coil containing protein 3 4 1721490-1745176 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005781, HPA006050, CAB010111, HPA022039 Supported Validated Endoplasmic reticulum
Centrosome
Cytosol Tissue enhanced 0 testis: 74.7 lymph node: 56.5 -UFL1 KIAA0776, Maxer, NLBP, RCAD ENSG00000014123 UFM1-specific ligase 1 6 96521595-96555276 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030558, HPA030559, HPA030560 Supported Supported Endoplasmic reticulum Expressed in all thyroid gland: 46.9 -POLA2 FLJ21662 ENSG00000014138 Polymerase (DNA directed), alpha 2, accessory subunit 11 65261762-65305589 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037570 Supported Supported Nucleoplasm Mixed tonsil: 13.3 -ZC3H3 KIAA0150, ZC3HDC3 ENSG00000014164 Zinc finger CCCH-type containing 3 8 143437655-143541453 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023658, HPA050577 Uncertain Uncertain Nucleoplasm
Golgi apparatus Expressed in all testis: 13.5 -CAPN1 CANP, CANPL1, muCANP, muCL ENSG00000014216 Calpain 1, (mu/I) large subunit 11 65180566-65212006 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005992 Supported Supported Cytosol Expressed in all esophagus: 245.3 -ACPP ACP-3, ACP3, PAP ENSG00000014257 Acid phosphatase, prostate 3 132317367-132368298 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000071, HPA004335, HPA063916 Supported Tissue enriched 153 prostate: 6368.2 esophagus: 41.6 -MDH1 ENSG00000014641 Malate dehydrogenase 1, NAD (soluble) 2 63588609-63607197 Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027296, CAB047333, HPA054276 Uncertain Supported Centrosome
Cytosol Expressed in all heart muscle: 736.3 -SLC30A9 C4orf1, GAC63, HUEL, ZNT9 ENSG00000014824 Solute carrier family 30 (zinc transporter), member 9 4 41990472-42090457 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004014 Approved Expressed in all parathyroid gland: 35.7 -MTMR11 CRA ENSG00000014914 Myotubularin related protein 11 1 149928651-149936898 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030351 Approved Approved Centrosome Mixed rectum: 27.7 -COX15 CEMCOX2 ENSG00000014919 Cytochrome c oxidase assembly homolog 15 (yeast) 10 99711844-99732100 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037727, HPA037728, HPA066096 Uncertain Supported Mitochondria Expressed in all thyroid gland: 36.2 -CCDC88C DAPLE, HkRP2, KIAA1509, SCA40 ENSG00000015133 Coiled-coil domain containing 88C 14 91271323-91417844 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005832 Approved Approved Nucleus
Nucleoli fibrillar center Mixed lymph node: 22.5 -YAF2 ENSG00000015153 YY1 associated factor 2 12 42157104-42238349 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026867 Supported Supported Nucleoplasm Expressed in all cerebral cortex: 29.5 -ZMYND11 BS69 ENSG00000015171 Zinc finger, MYND-type containing 11 10 134465-254637 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015816 Supported Nucleoplasm Expressed in all parathyroid gland: 196.6 -WAS IMD2, THC, WASP, WASPA ENSG00000015285 Wiskott-Aldrich syndrome X 48676596-48691427 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002022, CAB004290 Supported Tissue enhanced 0 appendix: 71.0;lymph node: 61.6;spleen: 70.8 bone marrow: 37.6 -DPEP1 ENSG00000015413 Dipeptidase 1 (renal) 16 89613308-89638456 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009426, HPA012783 Supported Approved Nucleus
Cell Junctions Tissue enhanced 0 kidney: 262.3;small intestine: 426.5 pancreas: 92.8 -BID ENSG00000015475 BH3 interacting domain death agonist 22 17734138-17774770 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000722, CAB003771 Supported Supported Cytosol Expressed in all bone marrow: 54.6 -MATR3 KIAA0723, MGC9105, MPD2, VCPDM ENSG00000015479 Matrin 3 5 139293648-139331359 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033552, HPA036564, HPA036565 Supported Approved Nucleoplasm Expressed in all cerebral cortex: 334.1 -NPC1L1 ENSG00000015520 NPC1-like 1 7 44512535-44541315 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB070127, CAB070128 Supported Tissue enhanced 0 duodenum: 58.7;small intestine: 59.3 liver: 14.2 -XYLT2 PXYLT2, XT-II ENSG00000015532 Xylosyltransferase II 17 50346092-50363138 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016456 Approved Nuclear bodies
Cytosol Expressed in all stomach: 31.1 -RGPD5 BS-63, DKFZp686I1842, RGP5 ENSG00000015568 RANBP2-like and GRIP domain containing 5 2 109792758-109857695 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045704, HPA049497, HPA051675, HPA067564 Uncertain Uncertain Nuclear membrane
Vesicles Tissue enhanced 0 testis: 6.8 duodenum: 3.2 -STMN4 RB3 ENSG00000015592 Stathmin-like 4 8 27235323-27258420 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027765 Uncertain Golgi apparatus
Vesicles Tissue enriched 25 cerebral cortex: 339.4 adrenal gland: 13.4 -NUDCD3 KIAA1068 ENSG00000015676 NudC domain containing 3 7 44379121-44490880 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019136, HPA019528, HPA019529 Approved Approved Nucleus
Plasma membrane
Cytosol Mixed cerebral cortex: 12.4 -ISL1 Isl-1, ISLET1 ENSG00000016082 ISL LIM homeobox 1 5 51383391-51394738 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA057416 Uncertain Validated Nucleoplasm Group enriched 5 placenta: 10.6;prostate: 15.3;seminal vesicle: 25.6;stomach: 9.8 testis: 2.9 -CHDH ENSG00000016391 Choline dehydrogenase 3 53812335-53846390 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036633, HPA058130 Supported Tissue enhanced 0 kidney: 39.9 small intestine: 16.7 -IL20RA IL-20R1, ZCYTOR7 ENSG00000016402 Interleukin 20 receptor, alpha 6 136999971-137045180 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB024990, HPA042281 Approved Approved Cytosol Tissue enhanced 0 skin: 45.1 breast: 33.2 -CLCA1 CaCC, CLCRG1 ENSG00000016490 Chloride channel accessory 1 1 86468368-86500289 Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052787, HPA059301 Supported Group enriched 8 colon: 713.1;duodenum: 906.3;rectum: 1141.9;small intestine: 1551.5 appendix: 139.7 -CLCA4 CaCC2 ENSG00000016602 Chloride channel accessory 4 1 86547078-86580754 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017045 Uncertain Group enriched 6 colon: 253.7;esophagus: 366.8;rectum: 160.8 urinary bladder: 42.4 -GLT8D1 AD-017, FLJ14611 ENSG00000016864 Glycosyltransferase 8 domain containing 1 3 52694485-52706083 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010588 Approved Approved Mitochondria Expressed in all testis: 116.6 -ATP2C1 ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1 ENSG00000017260 ATPase, Ca++ transporting, type 2C, member 1 3 130850595-131016712 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010207, HPA035116, HPA069684 Supported Validated Golgi apparatus Expressed in all prostate: 136.8 -IGF1 IGF-I, IGF1A, IGFI ENSG00000017427 Insulin-like growth factor 1 (somatomedin C) 12 102395867-102480645 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048946 Approved Tissue enhanced 0 cervix, uterine: 126.3 smooth muscle: 97.4 -SLC38A5 JM24, SN2 ENSG00000017483 Solute carrier family 38, member 5 X 48458537-48470256 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047411 Approved Approved Vesicles
Plasma membrane
Cytosol Mixed pancreas: 50.0 -RALBP1 RIP, RIP1, RLIP76 ENSG00000017797 RalA binding protein 1 18 9475009-9538116 Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB046010, HPA046651 Approved Approved Nuclear membrane
Vesicles
Cytosol Expressed in all seminal vesicle: 69.8 -RUFY3 KIAA0871, RIPx, Singar1, ZFYVE30 ENSG00000018189 RUN and FYVE domain containing 3 4 70704204-70807315 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022952, HPA022970 Approved Supported Cytosol Expressed in all cerebral cortex: 143.4 -CNTN1 F3, GP135 ENSG00000018236 Contactin 1 12 40692442-41072418 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025200, HPA041060 Approved Tissue enhanced 0 cerebral cortex: 226.1 ovary: 65.4 -SLC11A1 LSH, NRAMP, NRAMP1 ENSG00000018280 Solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 2 218382029-218396894 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029590 Uncertain Tissue enhanced 0 appendix: 9.3;lung: 13.2 spleen: 4.8 -WWTR1 DKFZp586I1419, TAZ ENSG00000018408 WW domain containing transcription regulator 1 3 149517235-149736714 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007415, CAB017483, CAB068248 Approved Validated Nucleoplasm
Nuclear bodies
Cytosol Mixed endometrium: 70.7 -AGPS ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY ENSG00000018510 Alkylglycerone phosphate synthase 2 177392644-177543836 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030209, HPA030210, HPA030211 Supported Validated Peroxisomes Expressed in all parathyroid gland: 39.2 -CXorf56 FLJ22965 ENSG00000018610 Chromosome X open reading frame 56 X 119538149-119565408 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038245, HPA038617, HPA064831 Uncertain Approved Nucleus
Centrosome Expressed in all thyroid gland: 24.0 -ATP1A2 FHM2, MHP2 ENSG00000018625 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1 160115759-160143591 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022230 Approved Group enriched 6 cerebral cortex: 435.6;skeletal muscle: 307.1 heart muscle: 59.1 -TTC27 FLJ20272 ENSG00000018699 Tetratricopeptide repeat domain 27 2 32628032-32821051 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031246 Approved Approved Nucleoli
Mitochondria Expressed in all testis: 24.9 -ZNF582 FLJ30927 ENSG00000018869 Zinc finger protein 582 19 56375846-56393545 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028858 Uncertain Approved Nucleoplasm
Cytosol Mixed thyroid gland: 13.4 -VSIG2 CTH, CTXL ENSG00000019102 V-set and immunoglobulin domain containing 2 11 124747472-124752238 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035919, HPA050147 Supported Approved Nucleoplasm Tissue enhanced 0 stomach: 582.1 rectum: 153.8 -PHLDB1 FLJ00141, KIAA0638, LL5a ENSG00000019144 Pleckstrin homology-like domain, family B, member 1 11 118606440-118658038 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037959, HPA038448, HPA061506 Approved Approved Nucleoplasm Mixed adipose tissue: 76.1 -MARCO SCARA2 ENSG00000019169 Macrophage receptor with collagenous structure 2 118942166-118994660 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063793 Supported Approved Golgi apparatus
Vesicles Tissue enhanced 0 appendix: 125.3;lung: 288.5 adipose tissue: 77.1 -CYP24A1 CP24, CYP24, P450-CC24 ENSG00000019186 Cytochrome P450, family 24, subfamily A, polypeptide 1 20 54153449-54173973 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022261, HPA063771 Supported Supported Nucleoplasm
Plasma membrane
Mitochondria Tissue enhanced 0 endometrium: 24.8;urinary bladder: 52.7 placenta: 13.9 -PRDM11 PFM8 ENSG00000019485 PR domain containing 11 11 45095806-45235124 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057072 Approved Mixed thyroid gland: 13.9 -SYT13 KIAA1427 ENSG00000019505 Synaptotagmin XIII 11 45240301-45286319 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046224, HPA056602 Uncertain Supported Vesicles Tissue enhanced 0 cerebral cortex: 70.1;gallbladder: 33.0 small intestine: 14.7 -SNAI2 SLUG, SLUGH1, SNAIL2 ENSG00000019549 Snail family zinc finger 2 8 48917690-48921740 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB011671 Supported Approved Nucleus Mixed cervix: 67.1 -CD74 DHLAG ENSG00000019582 CD74 molecule, major histocompatibility complex, class II invariant chain 5 150401637-150412929 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002506, HPA010592 Supported Supported Golgi apparatus Expressed in all spleen: 6665.5 -HGF DFNB39, F-TCF, HGFB, HPTA, SF ENSG00000019991 Hepatocyte growth factor (hepapoietin A; scatter factor) 7 81699006-81770438 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010333, HPA040360, HPA044088 Approved Approved Centrosome
Cytosol Tissue enriched 16 placenta: 435.4 gallbladder: 27.6 -ZRANB1 TRABID ENSG00000019995 Zinc finger, RAN-binding domain containing 1 10 124942123-124988189 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029239, HPA029240, HPA029241 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 34.5 -NCDN NCDN-1, NCDN-2 ENSG00000020129 Neurochondrin 1 35557473-35567274 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023676 Supported Supported Supported Cytosol Tissue enriched 12 cerebral cortex: 285.2 adrenal gland: 22.8 -ADGRA2 DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5 ENSG00000020181 Adhesion G protein-coupled receptor A2 8 37784191-37844896 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012393 Uncertain Expressed in all seminal vesicle: 86.1 -ZFP64 dJ548G19.1, dJ831D17.1, FLJ10734, FLJ12628, ZNF338 ENSG00000020256 ZFP64 zinc finger protein 20 52051663-52204308 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035112, HPA058387 Uncertain Approved Nucleus Expressed in all skin: 13.9 -MNAT1 MAT1, RNF66 ENSG00000020426 MNAT CDK-activating kinase assembly factor 1 14 60734742-60969953 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000701, HPA001154, CAB004495 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 87.0 -SAMD4A DKFZP434H0350, hSmaug1, KIAA1053, SAMD4, Smaug, SMG, SMGA ENSG00000020577 Sterile alpha motif domain containing 4A 14 54567097-54793315 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043061, HPA065309 Approved Approved Cell Junctions
Cytosol Tissue enhanced 0 testis: 102.3 skeletal muscle: 32.7 -RUNX3 AML2, CBFA3, PEBP2A3 ENSG00000020633 Runt-related transcription factor 3 1 24899511-24965121 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004195, CAB025416, HPA059006 Supported Supported Nucleus
Cytosol Tissue enhanced 0 spleen: 51.3 bone marrow: 45.3 -MRE11A ATLD, MRE11 ENSG00000020922 MRE11 homolog A, double strand break repair nuclease 11 94415578-94493908 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002691, CAB004081 Supported Validated Nucleoplasm Expressed in all endometrium: 18.8 -PLEKHB1 KPL1, PHR1, PHRET1 ENSG00000021300 Pleckstrin homology domain containing, family B (evectins) member 1 11 73646178-73662819 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 7 cerebral cortex: 496.1;parathyroid gland: 145.9 thyroid gland: 48.2 -SERPINB1 anti-elastase, EI, ELANH2, PI2 ENSG00000021355 Serpin peptidase inhibitor, clade B (ovalbumin), member 1 6 2832332-2842006 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018871, HPA052642 Supported Expressed in all esophagus: 466.2 -CYP3A43 ENSG00000021461 Cytochrome P450, family 3, subfamily A, polypeptide 43 7 99828013-99866102 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA066463, HPA072245 Supported Uncertain Cytosol Tissue enriched 14 liver: 22.4 testis: 1.5 -SLC7A9 CSNU3 ENSG00000021488 Solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 19 32830509-32869766 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042591 Supported Group enriched 10 duodenum: 81.2;kidney: 69.6;small intestine: 125.7 liver: 8.9 -SPAST ADPSP, FSP2, KIAA1083, SPG4 ENSG00000021574 Spastin 2 32063611-32157637 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017311 Approved Approved Nucleoplasm
Cytosol Mixed cerebral cortex: 20.1 -NRXN3 C14orf60, KIAA0743 ENSG00000021645 Neurexin 3 14 78170373-79868290 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002727 Approved Tissue enhanced 0 cerebral cortex: 43.1;smooth muscle: 28.6 testis: 21.4 -OSBPL5 KIAA1534, ORP5 ENSG00000021762 Oxysterol binding protein-like 5 11 3087116-3166739 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038335, HPA038712, HPA058727 Approved Validated Vesicles Mixed spleen: 20.1 -AQR fSAP164, IBP160, KIAA0560 ENSG00000021776 Aquarius intron-binding spliceosomal factor 15 34851782-34969839 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040624, HPA055647 Validated Nucleoplasm Mixed testis: 10.1 -CPS1 ENSG00000021826 Carbamoyl-phosphate synthase 1, mitochondrial 2 210477682-210679107 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003781, HPA021400 Supported Approved Nucleoli Group enriched 24 duodenum: 241.2;liver: 697.3;small intestine: 147.2 testis: 15.2 -C8B ENSG00000021852 Complement component 8, beta polypeptide 1 56929210-56966140 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023694 Supported Tissue enriched 54 liver: 434.8 lung: 8.1 -FHL1 bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA ENSG00000022267 Four and a half LIM domains 1 X 136146702-136211359 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001040, HPA001391, CAB020817 Supported Supported Plasma membrane
Cytosol Expressed in all skeletal muscle: 3805.6 -RTFDC1 C20orf43, CDAO5, HSPC164 ENSG00000022277 Replication termination factor 2 domain containing 1 20 56468585-56519449 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053986 Approved Approved Nucleus
Nucleoli Expressed in all cerebral cortex: 140.7 -GABRA1 EJM5 ENSG00000022355 Gamma-aminobutyric acid (GABA) A receptor, alpha 1 5 161847191-161899981 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022502, HPA055746 Supported Tissue enriched 44 cerebral cortex: 109.1 adrenal gland: 2.4 -NLRP2 CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2 ENSG00000022556 NLR family, pyrin domain containing 2 19 54953130-55001142 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020765, HPA021183 Uncertain Supported Golgi apparatus
Vesicles
Cytosol Mixed testis: 6.3 -SLC45A4 KIAA1126 ENSG00000022567 Solute carrier family 45, member 4 8 141207166-141308305 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023154 Uncertain Approved Plasma membrane Mixed testis: 21.1 -RNF10 KIAA0262, RIE2 ENSG00000022840 Ring finger protein 10 12 120533480-120577594 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052643 Approved Approved Nucleoplasm
Mitochondria Expressed in all testis: 178.9 -ZNF839 C14orf131 ENSG00000022976 Zinc finger protein 839 14 102317377-102342702 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA020434 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all testis: 36.9 -ZDHHC6 FLJ21952, ZNF376 ENSG00000023041 Zinc finger, DHHC-type containing 6 10 112424428-112446917 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014357 Approved Expressed in all small intestine: 51.7 -GRAMD1B KIAA1201 ENSG00000023171 GRAM domain containing 1B 11 123454398-123627774 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008557 Approved Approved Nucleus
Nucleoli
Intermediate filaments Tissue enhanced 0 adrenal gland: 87.8 cerebral cortex: 39.0 -RNH1 RAI, RNH ENSG00000023191 Ribonuclease/angiogenin inhibitor 1 11 494512-507300 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039223, HPA040781 Approved Validated Nucleoplasm
Cytosol Expressed in all skin: 73.2 -NDUFS1 CI-75k ENSG00000023228 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 2 206114817-206159603 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064605, CAB070844 Approved Supported Mitochondria Expressed in all heart muscle: 141.0 -RB1CC1 ATG17, Cc1, DRAGOU14, FIP200, KIAA0203, PPP1R131 ENSG00000023287 RB1-inducible coiled-coil 1 8 52622456-52745843 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024391, HPA053049 Approved Supported Nuclear membrane
Cytosol Expressed in all testis: 63.1 -ERP44 KIAA0573, PDIA10, TXNDC4 ENSG00000023318 Endoplasmic reticulum protein 44 9 99979179-100099040 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001318 Supported Expressed in all epididymis: 47.1 -ALAS1 ALAS, ALAS3 ENSG00000023330 5'-aminolevulinate synthase 1 3 52198086-52214327 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017498, HPA035860 Supported Validated Nucleoplasm
Mitochondria Expressed in all adrenal gland: 765.5 -BIRC3 API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49 ENSG00000023445 Baculoviral IAP repeat containing 3 11 102317450-102339403 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002317 Supported Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 lymph node: 139.7 appendix: 121.3 -AKAP11 AKAP220, DKFZp781I12161, FLJ11304, KIAA0629, PPP1R44, PRKA11 ENSG00000023516 A kinase (PRKA) anchor protein 11 13 42272153-42323267 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039089 Supported Approved Nucleoli
Plasma membrane
Cytosol Expressed in all cerebral cortex: 51.7 -GLRX2 bA101E13.1, GRX2 ENSG00000023572 Glutaredoxin 2 1 193096468-193106114 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023087, HPA057224 Supported Validated Nucleoplasm Expressed in all testis: 46.1 -SNAPC1 PTFgamma, SNAP43 ENSG00000023608 Small nuclear RNA activating complex, polypeptide 1, 43kDa 14 61762357-61796428 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029311 Supported Nucleoplasm Mixed testis: 35.6 -DERA CGI-26, DEOC ENSG00000023697 Deoxyribose-phosphate aldolase (putative) 12 15911172-16037282 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055897 Supported Nucleus Expressed in all kidney: 74.2 -STRAP MAWD, pt-wd, UNRIP ENSG00000023734 Serine/threonine kinase receptor associated protein 12 15882391-15903478 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027320, HPA055557, HPA073876 Approved Validated Nucleoplasm
Cytosol Expressed in all cerebral cortex: 144.6 -ABCC2 CMOAT, cMRP, DJS, MRP2 ENSG00000023839 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 10 99782732-99852192 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004860, CAB037271 Approved Group enriched 10 duodenum: 44.7;gallbladder: 42.8;kidney: 20.8;liver: 67.6;small intestine: 50.5 breast: 4.3 -DEF6 IBP, SLAT, SWAP70L ENSG00000023892 DEF6 guanine nucleotide exchange factor 6 35297852-35321771 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038975, HPA038976 Supported Validated Nucleoplasm Mixed lymph node: 56.9 -PLEKHO1 CKIP-1, OC120 ENSG00000023902 Pleckstrin homology domain containing, family O member 1 1 150149183-150164720 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061018 Approved Mitochondria Mixed appendix: 80.3 -GCLM GLCLR ENSG00000023909 Glutamate-cysteine ligase, modifier subunit 1 93885205-93909456 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009568, HPA023696, CAB040554 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all thyroid gland: 28.1 -UBR2 bA49A4.1, C6orf133, dJ392M17.3, KIAA0349 ENSG00000024048 Ubiquitin protein ligase E3 component n-recognin 2 6 42564062-42693504 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027869, HPA027880 Approved Approved Nucleoplasm
Plasma membrane Expressed in all parathyroid gland: 30.0 -EHD2 PAST2 ENSG00000024422 EH-domain containing 2 19 47713343-47743134 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047394, HPA049890, HPA049986, HPA066751 Approved Supported Plasma membrane Tissue enhanced 0 adipose tissue: 208.4 smooth muscle: 110.4 -DEPDC1 DEP.8, DEPDC1A, FLJ20354, SDP35 ENSG00000024526 DEP domain containing 1 1 68474152-68497221 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017845 Approved Supported Nucleus
Nucleoli fibrillar center Tissue enhanced 0 testis: 14.4 lymph node: 5.8 -CCDC28A C6orf80, CCRL1AP, DKFZp586D0623 ENSG00000024862 Coiled-coil domain containing 28A 6 138773509-138793319 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055125 Approved Approved Cytosol Expressed in all thyroid gland: 90.3 -RRAGD bA11D8.2.1, DKFZP761H171 ENSG00000025039 Ras-related GTP binding D 6 89364636-89412270 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA068664 Approved Approved Nucleoplasm
Centrosome Expressed in all thyroid gland: 46.7 -HSF2 ENSG00000025156 Heat shock transcription factor 2 6 122399546-122433119 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016067, HPA031455 Approved Supported Nucleoplasm Expressed in all testis: 71.1 -PHF20 C20orf104, dJ1121G12.1, TDRD20A ENSG00000025293 PHD finger protein 20 20 35771974-35950381 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029619, HPA029620, HPA029621 Approved Supported Nucleoplasm
Nuclear membrane
Cytosol Expressed in all testis: 26.0 -HSD17B6 HSE, RODH, SDR9C6 ENSG00000025423 Hydroxysteroid (17-beta) dehydrogenase 6 12 56752161-56787790 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059141 Supported Approved Nucleus
Vesicles Tissue enriched 10 liver: 929.1 seminal vesicle: 94.8 -NR1H3 LXR-a, RLD-1 ENSG00000025434 Nuclear receptor subfamily 1, group H, member 3 11 47248300-47269032 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA036443, CAB037109 Approved Expressed in all adipose tissue: 55.1 -TYMP ECGF1, MNGIE ENSG00000025708 Thymidine phosphorylase 22 50525752-50530056 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000530, HPA001072, CAB002518 Approved Approved Nuclear bodies
Golgi apparatus Tissue enhanced 0 appendix: 103.2 spleen: 54.0 -NCAPH2 384D8-2, CAP-H2, hCAP-H2 ENSG00000025770 Non-SMC condensin II complex, subunit H2 22 50508216-50523472 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067932, HPA069056 Supported Validated Nucleoplasm
Cytokinetic bridge Expressed in all bone marrow: 49.6 -TOMM34 HTOM34P, TOM34 ENSG00000025772 Translocase of outer mitochondrial membrane 34 20 44942130-44960486 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018845, HPA056875 Supported Validated Cytosol Expressed in all testis: 181.6 -SEC63 DNAJC23, ERdj2, PRO2507, SEC63L ENSG00000025796 SEC63 homolog, protein translocation regulator 6 107867756-107958189 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053295, HPA060535 Supported Supported Endoplasmic reticulum Expressed in all thyroid gland: 87.1 -KPNA6 FLJ11249, IPOA7, KPNA7, MGC17918 ENSG00000025800 Karyopherin alpha 6 (importin alpha 7) 1 32108038-32176568 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018863 Supported Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 48.5 -VIM ENSG00000026025 Vimentin 10 17228259-17237593 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000080, HPA001762, CAB058687 Supported Supported Intermediate filaments Expressed in all ovary: 4341.9 -FAS APO-1, APT1, CD95, FAS1, TNFRSF6 ENSG00000026103 Fas cell surface death receptor 10 88990531-89015785 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027444 Approved Approved Plasma membrane
Cytosol Mixed lung: 39.5 -RNASET2 bA514O12.3, FLJ10907, RNASE6PL ENSG00000026297 Ribonuclease T2 6 166929504-166957191 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029013, HPA066509 Approved Expressed in all spleen: 284.2 -CD44 CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1 ENSG00000026508 CD44 molecule (Indian blood group) 11 35138870-35232402 Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000112, CAB000316, HPA005785 Supported Validated Golgi apparatus
Plasma membrane Expressed in all skin: 505.8 -KCNG1 K13, KCNG, kH2, Kv6.1 ENSG00000026559 Potassium channel, voltage gated modifier subfamily G, member 1 20 51003656-51023129 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039530, HPA040024 Approved Validated Vesicles Tissue enhanced 0 endometrium: 23.4;seminal vesicle: 17.9 placenta: 10.8 -AGPAT4 dJ473J16.2, LPAAT-delta ENSG00000026652 1-acylglycerol-3-phosphate O-acyltransferase 4 6 161129979-161274061 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053287, HPA060525 Approved Approved Nucleoli
Golgi apparatus
Vesicles Tissue enhanced 0 cerebral cortex: 24.8 placenta: 12.2 -SLAMF7 19A, CD319, CRACC, CS1 ENSG00000026751 SLAM family member 7 1 160739057-160754821 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015445, HPA055945, HPA061654 Supported Approved Vesicles Mixed spleen: 59.2 -BTN3A1 BT3.1, BTF5, BTN3.1, CD277 ENSG00000026950 Butyrophilin, subfamily 3, member A1 6 26402237-26415216 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012565 Approved Uncertain Vesicles Expressed in all spleen: 114.2 -MIPEP MIP ENSG00000027001 Mitochondrial intermediate peptidase 13 23730189-23889419 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030676, HPA031669, HPA031670 Approved Validated Mitochondria Expressed in all fallopian tube: 27.1 -PRKCH PKC-L, PKCL, PRKCL ENSG00000027075 Protein kinase C, eta 14 61187559-61550976 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026294, HPA053709 Approved Approved Plasma membrane
Cytosol Expressed in all lymph node: 62.3 -INSRR IRR ENSG00000027644 Insulin receptor-related receptor 1 156840063-156859018 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA025285 Uncertain Tissue enhanced 0 adrenal gland: 1.8;kidney: 1.4;testis: 2.2 prostate: 0.6 -IFNGR1 CD119, IFNGR ENSG00000027697 Interferon gamma receptor 1 6 137197484-137219449 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029213, HPA063871 Approved Supported Endoplasmic reticulum
Vesicles
Plasma membrane Expressed in all spleen: 225.2 -B4GALT7 beta4Gal-T7, XGALT-1 ENSG00000027847 Xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 5 177600100-177610347 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042330 Supported Expressed in all thyroid gland: 27.2 -SH2D2A F2771, TSAd ENSG00000027869 SH2 domain containing 2A 1 156806243-156816862 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 15.5 lymph node: 10.7 -VRK2 ENSG00000028116 Vaccinia related kinase 2 2 57907651-58159920 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046459, HPA047503 Approved Supported Endoplasmic reticulum Expressed in all thyroid gland: 29.2 -TNFRSF1B CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80 ENSG00000028137 Tumor necrosis factor receptor superfamily, member 1B 1 12167003-12209228 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004796 Approved Tissue enhanced 0 appendix: 103.0 spleen: 79.2 -VEZT DKFZP761C241 ENSG00000028203 Vezatin, adherens junctions transmembrane protein 12 95217746-95302790 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004811, HPA017066 Approved Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 31.2 -POU2F2 OCT2, OTF2 ENSG00000028277 POU class 2 homeobox 2 19 42086110-42196585 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002513, HPA040368, HPA062096, HPA064404 Supported Supported Nucleoplasm Group enriched 6 appendix: 37.8;lymph node: 62.5;spleen: 37.2;tonsil: 45.5 urinary bladder: 8.1 -BRD9 FLJ13441 ENSG00000028310 Bromodomain containing 9 5 850291-892824 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021465, HPA023197 Uncertain Approved Nucleoplasm Expressed in all cerebral cortex: 14.8 -SNX1 HsT17379, MGC8664, SNX1A, Vps5 ENSG00000028528 Sorting nexin 1 15 64094123-64146090 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047373, HPA052761 Approved Validated Endosomes
Lysosomes Expressed in all thyroid gland: 162.7 -TBPL1 STUD, TLF, TLP, TRF2 ENSG00000028839 TBP-like 1 6 133952170-133990432 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071810, HPA071813 Approved Validated Nucleoplasm
Nucleoli Tissue enriched 8 testis: 226.1 thyroid gland: 28.1 -ARNTL2 bHLHe6, BMAL2, CLIF, MOP9, PASD9 ENSG00000029153 Aryl hydrocarbon receptor nuclear translocator-like 2 12 27332854-27425289 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059074, HPA065355 Uncertain Validated Nucleus
Nucleoli Tissue enhanced 0 esophagus: 31.3 tonsil: 21.0 -BCLAF1 BTF, KIAA0164 ENSG00000029363 BCL2-associated transcription factor 1 6 136256863-136289851 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006484, HPA006669, HPA027770 Supported Validated Nuclear speckles Expressed in all bone marrow: 91.1 -SLC39A9 FLJ11274 ENSG00000029364 Solute carrier family 39, member 9 14 69398015-69462388 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA007921, HPA075390 Approved Approved Endoplasmic reticulum Expressed in all parathyroid gland: 44.1 -ANK1 ANK, SPH1 ENSG00000029534 Ankyrin 1, erythrocytic 8 41653220-41896762 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004842, CAB016057, HPA056953 Supported Tissue enhanced 0 parathyroid gland: 83.0;skeletal muscle: 348.3 heart muscle: 65.3 -IBSP BSP, BSP-II, SP-II ENSG00000029559 Integrin-binding sialoprotein 4 87799581-87812435 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 1.6;cervix, uterine: 1.3 placenta: 0.3 -TFB1M CGI-75, mtTFB ENSG00000029639 Transcription factor B1, mitochondrial 6 155257509-155314493 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029428 Approved Mixed testis: 19.6 -RABEP1 neurocrescin, RAB5EP, rabaptin-5, RABPT5 ENSG00000029725 Rabaptin, RAB GTPase binding effector protein 1 17 5282265-5385812 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004549, HPA019669, HPA024235, HPA024691 Supported Validated Vesicles Expressed in all parathyroid gland: 89.9 -HMGB3 HMG2A, HMG4, MGC90319 ENSG00000029993 High mobility group box 3 X 150980509-150990775 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062583 Supported Approved Nucleus
Nucleoli Expressed in all placenta: 195.7 -NUP160 FLJ22583, KIAA0197 ENSG00000030066 Nucleoporin 160kDa 11 47778087-47848555 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 38.8 -BAK1 BAK, BCL2L7, CDN1 ENSG00000030110 BCL2-antagonist/killer 1 6 33572547-33580293 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005029 Supported Expressed in all duodenum: 49.2 -MUSK ENSG00000030304 Muscle, skeletal, receptor tyrosine kinase 9 110668771-110801620 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed testis: 3.0 -IKZF2 Helios, ZNFN1A2 ENSG00000030419 IKAROS family zinc finger 2 (Helios) 2 212999691-213152427 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059142 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Mixed esophagus: 21.4 -GRN CLN11, PCDGF, PGRN ENSG00000030582 Granulin 17 44345086-44353102 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008763, CAB019394, HPA028747 Approved Validated Endoplasmic reticulum
Endosomes
Lysosomes Expressed in all lung: 425.0 -FAM13B ARHGAP49, C5orf5, FAM13B1, KHCHP, N61 ENSG00000031003 Family with sequence similarity 13, member B 5 137937960-138051961 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036525, HPA041819, HPA071936 Uncertain Approved Nucleoplasm Expressed in all testis: 66.0 -ARHGAP31 CDGAP ENSG00000031081 Rho GTPase activating protein 31 3 119294373-119420714 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036380 Approved Mixed lung: 29.2 -CENPQ C6orf139, CENP-Q, FLJ10545 ENSG00000031691 Centromere protein Q 6 49463378-49493107 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029043, HPA046634, HPA054965 Approved Validated Nucleoplasm Mixed testis: 11.0 -SARS SERS ENSG00000031698 Seryl-tRNA synthetase 1 109213918-109238169 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016939, HPA064668 Uncertain Validated Cytosol Expressed in all thyroid gland: 240.2 -RANBP3 ENSG00000031823 RAN binding protein 3 19 5916139-5978142 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043375, HPA043389 Supported Validated Nucleoplasm Expressed in all testis: 60.1 -ARID4A RBBP1, RBP-1, RBP1 ENSG00000032219 AT rich interactive domain 4A (RBP1-like) 14 58298385-58373887 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048899 Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all cerebral cortex: 24.1 -TSSC1 ENSG00000032389 Tumor suppressing subtransferable candidate 1 2 3188925-3377882 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031231, HPA031232, HPA031233, HPA031234 Approved Supported Nucleus
Nucleoli
Intermediate filaments Expressed in all thyroid gland: 34.7 -PNPLA6 iPLA2delta, NTE, SPG39, sws ENSG00000032444 Patatin-like phospholipase domain containing 6 19 7534004-7561764 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007522 Uncertain Expressed in all testis: 49.2 -IFT88 D13S1056E, hTg737, MGC26259, Tg737, TTC10 ENSG00000032742 Intraflagellar transport 88 13 20567069-20691437 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Expressed in all testis: 125.9 -ALG1 HMAT1, HMT-1 ENSG00000033011 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 16 5033960-5087379 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060392 Approved Approved Nucleoli fibrillar center
Endoplasmic reticulum Expressed in all parathyroid gland: 32.8 -ZCCHC8 DKFZp434E2220 ENSG00000033030 Zinc finger, CCHC domain containing 8 12 122471600-122501073 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037483, HPA037484 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all bone marrow: 33.1 -ABCF2 ABC28, EST133090, HUSSY-18, M-ABC1 ENSG00000033050 ATP-binding cassette, sub-family F (GCN20), member 2 7 151207837-151227230 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020091, CAB020682, HPA021815, HPA030388 Supported Supported Cytosol Expressed in all parathyroid gland: 51.2 -CHPF2 ChSy-3, CSGlcA-T, KIAA1402 ENSG00000033100 Chondroitin polymerizing factor 2 7 151232489-151238827 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA020992 Approved Approved Nucleoplasm
Cytosol Expressed in all appendix: 24.0 -LRRC7 densin-180, KIAA1365 ENSG00000033122 Leucine rich repeat containing 7 1 69568398-70151945 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 14.5 testis: 4.3 -FUT8 ENSG00000033170 Fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 14 65410592-65744121 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017129, HPA040863, HPA043410 Supported Validated Golgi apparatus
Cytosol Mixed cerebral cortex: 31.6 -UBA6 FLJ10808, UBE1L2 ENSG00000033178 Ubiquitin-like modifier activating enzyme 6 4 67612652-67701179 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037001 Uncertain Validated Nucleoplasm
Cytosol Expressed in all testis: 18.6 -GAB2 KIAA0571 ENSG00000033327 GRB2-associated binding protein 2 11 78215297-78418348 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000271, HPA001368, CAB022159 Approved Supported Plasma membrane Expressed in all cerebral cortex: 35.6 -ATP6V0A1 a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1 ENSG00000033627 ATPase, H+ transporting, lysosomal V0 subunit a1 17 42458844-42522611 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022144 Supported Approved Nuclear speckles
Golgi apparatus
Vesicles
Cytosol Expressed in all cerebral cortex: 201.5 -PIAS1 DDXBP1, GBP, GU/RH-II, ZMIZ3 ENSG00000033800 Protein inhibitor of activated STAT, 1 15 68054179-68198603 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005743, CAB012304 Supported Approved Microtubules Expressed in all testis: 37.6 -SLC4A7 NBC3, SBC2, SLC4A6 ENSG00000033867 Solute carrier family 4, sodium bicarbonate cotransporter, member 7 3 27372721-27484420 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022494, HPA035857 Supported Supported Plasma membrane
Focal adhesion sites Tissue enhanced 0 duodenum: 59.2 breast: 23.6 -APBA2 D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11L ENSG00000034053 Amyloid beta (A4) precursor protein-binding, family A, member 2 15 28884483-29118315 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB037065, HPA039400 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles
Plasma membrane Tissue enhanced 0 cerebral cortex: 12.2 spleen: 3.3 -MAP2K3 MAPKK3, MEK3, MKK3, PRKMK3 ENSG00000034152 Mitogen-activated protein kinase kinase 3 17 21284672-21315240 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018548 Approved Supported Nucleoplasm
Cytosol Expressed in all bone marrow: 130.3 -EFCAB1 FLJ11767 ENSG00000034239 EF-hand calcium binding domain 1 8 48710789-48735311 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA023527, HPA069955 Supported Approved Nucleoplasm
Plasma membrane Tissue enhanced 0 fallopian tube: 148.1;testis: 46.9 ovary: 23.8 -TMSB10 TB10 ENSG00000034510 Thymosin beta 10 2 84905625-84906675 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all epididymis: 3641.5 -ASTE1 HT001 ENSG00000034533 Asteroid homolog 1 (Drosophila) 3 131013875-131027649 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037010, HPA037011 Supported Approved Endoplasmic reticulum Mixed thyroid gland: 11.7 -RNF19A DKFZp566B1346, dorfin, RNF19 ENSG00000034677 Ring finger protein 19A, RBR E3 ubiquitin protein ligase 8 100257059-100410015 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB011455, HPA023652 Approved Expressed in all testis: 98.8 -PEX3 ENSG00000034693 Peroxisomal biogenesis factor 3 6 143450807-143490010 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042830, HPA058006 Supported Supported Nucleoplasm
Peroxisomes Expressed in all adrenal gland: 54.6 -GABARAPL2 ATG8, ATG8C, GATE-16, GATE16, GEF2 ENSG00000034713 GABA(A) receptor-associated protein like 2 16 75566351-75577881 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036726 Uncertain Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 320.2 -MYOC GLC1A, JOAG1, TIGR ENSG00000034971 Myocilin, trabecular meshwork inducible glucocorticoid response 1 171635417-171652683 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027364 Approved Tissue enhanced 0 adipose tissue: 45.9 esophagus: 21.5 -SH3YL1 DKFZP586F1318, Ray ENSG00000035115 SH3 and SYLF domain containing 1 2 217730-266398 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030926, HPA030927 Approved Approved Nucleus Expressed in all kidney: 149.0 -FAM136A FLJ14668 ENSG00000035141 Family with sequence similarity 136, member A 2 70295975-70302090 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030103, HPA030104 Approved Approved Mitochondria Expressed in all thyroid gland: 34.7 -VCL ENSG00000035403 Vinculin 10 73995193-74121363 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002131, CAB002453, HPA063777 Supported Validated Focal adhesion sites Expressed in all smooth muscle: 339.0 -DEPDC1B BRCC3, XTP1 ENSG00000035499 DEP domain containing 1B 5 60596912-60700190 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038255, HPA072558 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced 0 gallbladder: 33.1;testis: 22.4 lymph node: 10.9 -DAPK2 DRP-1, MGC119312 ENSG00000035664 Death-associated protein kinase 2 15 63907036-64072033 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071581 Supported Golgi apparatus
Vesicles Tissue enhanced 0 thyroid gland: 48.9 lung: 29.9 -NSMAF FAN ENSG00000035681 Neutral sphingomyelinase (N-SMase) activation associated factor 8 58583504-58659844 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023067, HPA023148, HPA023151 Uncertain Approved Nucleoli Expressed in all parathyroid gland: 33.0 -ADSS ENSG00000035687 Adenylosuccinate synthase 1 244408494-244452134 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024400 Supported Supported Plasma membrane
Cytosol Expressed in all testis: 116.4 -STAP1 BRDG1, STAP-1 ENSG00000035720 Signal transducing adaptor family member 1 4 67558728-67607337 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038529 Supported Uncertain Nucleoplasm
Vesicles Group enriched 6 appendix: 24.7;kidney: 13.1;lymph node: 60.3;spleen: 27.0;tonsil: 58.9 testis: 6.1 -TIMP2 CSC-21K ENSG00000035862 TIMP metallopeptidase inhibitor 2 17 78852977-78925387 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010203 Approved Expressed in all ovary: 1176.3 -RFC1 A1, MHCBFB, PO-GA, RFC140 ENSG00000035928 Replication factor C (activator 1) 1, 145kDa 4 39287456-39366375 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009520, HPA046116, HPA069306 Supported Validated Nucleus Expressed in all parathyroid gland: 65.4 -TBC1D23 FLJ11046 ENSG00000036054 TBC1 domain family, member 23 3 100261000-100325251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038151, HPA038152 Approved Validated Golgi apparatus Expressed in all testis: 32.8 -CUL3 ENSG00000036257 Cullin 3 2 224470150-224585397 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002678 Supported Expressed in all testis: 400.5 -MYOM2 ENSG00000036448 Myomesin 2 8 2045040-2165552 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001765, HPA005953 Supported Approved Mitochondria Group enriched 20 heart muscle: 204.1;skeletal muscle: 110.2 breast: 7.9 -OTC ENSG00000036473 Ornithine carbamoyltransferase X 38352545-38421450 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000243, HPA000570 Supported Supported Mitochondria Group enriched 25 duodenum: 117.6;liver: 195.0;small intestine: 98.9 colon: 5.3 -CYP46A1 CYP46 ENSG00000036530 Cytochrome P450, family 46, subfamily A, polypeptide 1 14 99684304-99727301 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040702 Uncertain Tissue enriched 19 cerebral cortex: 64.3 heart muscle: 3.3 -ZZZ3 ATAC1, DKFZP564I052 ENSG00000036549 Zinc finger, ZZ-type containing 3 1 77562416-77683419 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053663, HPA054913, HPA066197 Uncertain Approved Nucleus
Nucleoli Expressed in all thyroid gland: 32.7 -SLC18A1 CGAT, VAT1, VMAT1 ENSG00000036565 Solute carrier family 18 (vesicular monoamine transporter), member 1 8 20144855-20183206 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA006877, HPA063797 Supported Tissue enriched 10 adrenal gland: 32.8 rectum: 3.1 -USP2 UBP41 ENSG00000036672 Ubiquitin specific peptidase 2 11 119355215-119381726 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA006777, HPA007222 Approved Supported Plasma membrane
Cytosol Tissue enhanced 0 testis: 119.2 skeletal muscle: 59.3 -CASR FHH, GPRC2A, HHC, HHC1, NSHPT ENSG00000036828 Calcium-sensing receptor 3 122183683-122286503 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039686, HPA050335 Supported Tissue enriched 60 parathyroid gland: 1627.2 kidney: 27.0 -TUBG2 ENSG00000037042 Tubulin, gamma 2 17 42659305-42667006 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB011495 Approved Supported Microtubule organizing center Expressed in all cerebral cortex: 77.6 -RPL26L1 RPL26P1 ENSG00000037241 Ribosomal protein L26-like 1 5 172958729-172969771 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030449 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all testis: 124.7 -FLT4 PCL, VEGFR3 ENSG00000037280 Fms-related tyrosine kinase 4 5 180601506-180649624 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000099 Supported Nuclear speckles
Plasma membrane
Cell Junctions Mixed spleen: 18.6 -NSUN2 FLJ20303, Misu, MRT5, TRM4 ENSG00000037474 NOP2/Sun RNA methyltransferase family, member 2 5 6599239-6633291 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037896 Supported Supported Nucleus Expressed in all breast: 43.6 -FBXO42 Fbx42, KIAA1332 ENSG00000037637 F-box protein 42 1 16246839-16352454 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025071 Approved Approved Nucleoplasm Expressed in all skin: 30.0 -MFAP3 ENSG00000037749 Microfibrillar-associated protein 3 5 154038906-154220478 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015883, HPA049198 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 73.4 -MRI1 MGC3207, MRDI, mtnA, Ypr118w ENSG00000037757 Methylthioribose-1-phosphate isomerase 1 19 13764532-13774282 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042744, CAB045988 Approved Supported Nucleoplasm
Nucleoli fibrillar center
Cytosol Expressed in all placenta: 23.0 -METTL1 C12orf1, TRM8, TRMT8 ENSG00000037897 Methyltransferase like 1 12 57768471-57772793 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020914, HPA050450 Uncertain Validated Nucleus Expressed in all epididymis: 22.4 -HOXC8 HOX3, HOX3A ENSG00000037965 Homeobox C8 12 54009106-54012362 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA028911, CAB037020 Uncertain Approved Nucleoplasm
Microtubules Tissue enhanced 0 epididymis: 20.9;smooth muscle: 12.7 adrenal gland: 7.7 -AGA ASRG ENSG00000038002 Aspartylglucosaminidase 4 177430770-177442503 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031415, HPA031417 Supported Expressed in all epididymis: 34.7 -PI4K2B FLJ11105, PI4KIIB, PIK42B ENSG00000038210 Phosphatidylinositol 4-kinase type 2 beta 4 25233975-25279092 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004099 Approved Supported Cytosol Mixed duodenum: 34.2 -BOD1L1 BOD1L, FAM44A, FLJ33215, KIAA1327 ENSG00000038219 Biorientation of chromosomes in cell division 1-like 1 4 13568738-13627723 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036943, HPA037362, HPA041290 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 38.8 -MAT2B MATIIbeta, SDR23E1 ENSG00000038274 Methionine adenosyltransferase II, beta 5 163503114-163519336 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037721, HPA037722 Uncertain Expressed in all thyroid gland: 132.8 -TLL1 ENSG00000038295 Tolloid-like 1 4 165873258-166103895 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060767 Approved Vesicles Tissue enhanced 0 placenta: 10.4 gallbladder: 4.4 -EDC4 Ge-1, HEDLS, RCD-8 ENSG00000038358 Enhancer of mRNA decapping 4 16 67873023-67884503 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041164, HPA043038 Supported Validated Nucleoplasm
Cytoplasmic bodies Expressed in all parathyroid gland: 28.0 -TRIO ARHGEF23 ENSG00000038382 Trio Rho guanine nucleotide exchange factor 5 14143702-14532128 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008157, HPA064664 Supported Approved Vesicles
Cytosol Expressed in all breast: 30.8 -VCAN CSPG2, PG-M ENSG00000038427 Versican 5 83471465-83582303 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004726, CAB008979 Supported Supported Vesicles Tissue enhanced 0 appendix: 107.6;placenta: 103.8 smooth muscle: 66.2 -CLEC16A Gop-1, KIAA0350 ENSG00000038532 C-type lectin domain family 16, member A 16 10944488-11182189 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035814, HPA035815, HPA061385 Approved Approved Nucleus
Vesicles Expressed in all testis: 60.2 -MSR1 CD204, SCARA1 ENSG00000038945 Macrophage scavenger receptor 1 8 16107878-16567490 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000272, CAB032491 Supported Tissue enhanced 0 lung: 188.3 gallbladder: 50.3 -CDH1 CD324, UVO, uvomorulin ENSG00000039068 Cadherin 1, type 1 16 68737225-68835548 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857 Supported Supported Golgi apparatus
Plasma membrane
Cell Junctions Tissue enhanced 0 parathyroid gland: 467.0 thyroid gland: 264.7 -SKIV2L2 Dob1, fSAP118, KIAA0052, Mtr4 ENSG00000039123 Superkiller viralicidic activity 2-like 2 (S. cerevisiae) 5 55307760-55425581 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037379 Supported Supported Nucleus Expressed in all parathyroid gland: 42.3 -DNAH5 CILD3, Dnahc5, HL1, KTGNR, PCD ENSG00000039139 Dynein, axonemal, heavy chain 5 5 13690331-13944543 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037469, HPA037470 Supported Tissue enhanced 0 fallopian tube: 6.1;lung: 2.6 breast: 2.0 -ZFYVE16 KIAA0305, PPP1R69 ENSG00000039319 Zinc finger, FYVE domain containing 16 5 80408013-80479350 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035935, HPA035936 Supported Validated Vesicles
Cytosol Mixed cervix: 25.1 -FAM65A FLJ13725 ENSG00000039523 Family with sequence similarity 65, member A 16 67518418-67546788 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005923 Uncertain Approved Golgi apparatus
Cytosol Expressed in all spleen: 60.7 -C6 ENSG00000039537 Complement component 6 5 41142234-41261438 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043823, CAB069427 Supported Group enriched 7 fallopian tube: 72.6;liver: 357.7 heart muscle: 30.6 -RAI14 DKFZp564G013, KIAA1334, NORPEG, RAI13 ENSG00000039560 Retinoic acid induced 14 5 34656237-34832627 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036949, HPA036950 Supported Supported Nucleus
Actin filaments
Cytosol Mixed endometrium: 91.6 -SOX30 ENSG00000039600 SRY (sex determining region Y)-box 30 5 157625679-157671480 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006159, CAB009382 Supported Tissue enriched 90 testis: 144.0 fallopian tube: 1.6 -PNKP PNK ENSG00000039650 Polynucleotide kinase 3'-phosphatase 19 49861204-49878351 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006782 Supported Supported Nucleus
Nucleoli Expressed in all spleen: 30.5 -BEST2 FLJ20132, VMD2L1 ENSG00000039987 Bestrophin 2 19 12751702-12758458 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046229 Approved Tissue enhanced 0 colon: 15.8;rectum: 15.4 tonsil: 4.9 -PHLPP2 KIAA0931, PHLPPL ENSG00000040199 PH domain and leucine rich repeat protein phosphatase 2 16 71637835-71724701 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048598 Approved Approved Vesicles Mixed small intestine: 24.6 -SPDL1 CCDC99, FLJ20364, hSpindly ENSG00000040275 Spindle apparatus coiled-coil protein 1 5 169583634-169604778 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044700, HPA048146 Approved Approved Cytosol Tissue enhanced 0 testis: 60.8 lymph node: 16.6 -STAU2 39K2 ENSG00000040341 Staufen double-stranded RNA binding protein 2 8 73420369-73747708 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019155, CAB020836 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 74.3 -PQLC2 FLJ20320 ENSG00000040487 PQ loop repeat containing 2 1 19312326-19329300 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA057810 Approved Validated Vesicles Expressed in all testis: 16.3 -CTNS CTNS-LSB, PQLC4 ENSG00000040531 Cystinosin, lysosomal cystine transporter 17 3636468-3661542 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA046947 Supported Vesicles
Intermediate filaments Expressed in all testis: 43.3 -RTN4R NOGOR ENSG00000040608 Reticulon 4 receptor 22 20241415-20283246 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012443 Supported Plasma membrane
Actin filaments
Focal adhesion sites Tissue enhanced 0 cerebral cortex: 23.8 spleen: 5.1 -PHF23 FLJ16355, MGC2941 ENSG00000040633 PHD finger protein 23 17 7235028-7239722 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052410 Approved Validated Nucleoplasm Expressed in all testis: 41.7 -CDH10 ENSG00000040731 Cadherin 10, type 2 (T2-cadherin) 5 24487100-24644978 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010651 Approved Group enriched 19 cerebral cortex: 32.7;prostate: 6.8 adrenal gland: 1.0 -INPP4A INPP4 ENSG00000040933 Inositol polyphosphate-4-phosphatase type I A 2 98444854-98594390 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001628 Approved Approved Nucleus
Nuclear membrane Expressed in all cerebral cortex: 38.8 -RAB27B ENSG00000041353 RAB27B, member RAS oncogene family 18 54717860-54895516 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017712, HPA019849 Approved Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 stomach: 40.5 prostate: 31.5 -PSMA4 HC9, HsT17706 ENSG00000041357 Proteasome subunit alpha 4 15 78540405-78552419 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004973, HPA055466, HPA060613 Supported Validated Nucleus
Vesicles
Cytosol Expressed in all testis: 173.1 -MYO16 KIAA0865, Myo16b, MYR8, NYAP3, PPP1R107 ENSG00000041515 Myosin XVI 13 108596152-109208007 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040110, HPA058769, HPA071948 Uncertain Approved Vesicles Tissue enhanced 0 cerebral cortex: 2.2 testis: 1.0 -LSG1 FLJ11301 ENSG00000041802 Large 60S subunit nuclear export GTPase 1 3 194640788-194672477 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037704, HPA037705 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all testis: 24.8 -PARP3 ADPRT3, ADPRTL3, hPARP-3, IRT1, pADPRT-3 ENSG00000041880 Poly (ADP-ribose) polymerase family, member 3 3 51942345-51948867 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA067657 Supported Approved Nucleoli
Cytosol Mixed parathyroid gland: 52.0 -TNC DFNA56, HXB, MGC167029, TN ENSG00000041982 Tenascin C 9 115019578-115118257 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004592, HPA004823 Approved Tissue enhanced 0 appendix: 243.6;smooth muscle: 522.1 adipose tissue: 77.9 -THAP3 ENSG00000041988 THAP domain containing, apoptosis associated protein 3 1 6624866-6635586 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA067114 Approved Approved Nucleus Expressed in all ovary: 17.8 -FAM65C C20orf175, C20orf176, dJ530I15.2, dJ530I15.3 ENSG00000042062 Family with sequence similarity 65, member C 20 50586108-50691528 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051823, HPA054759 Uncertain Approved Nucleoplasm Mixed endometrium: 18.2 -TDP1 FLJ11090, SCAN1 ENSG00000042088 Tyrosyl-DNA phosphodiesterase 1 14 89954939-90044768 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071317 Supported Nucleus
Plasma membrane Mixed testis: 41.7 -AIFM2 AMID, FLJ14497, PRG3 ENSG00000042286 Apoptosis-inducing factor, mitochondrion-associated, 2 10 70098223-70132934 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028961, HPA042309 Approved Approved Cytosol Tissue enhanced 0 adipose tissue: 42.6 thyroid gland: 17.9 -C2orf83 DKFZp547H025 ENSG00000042304 Chromosome 2 open reading frame 83 2 227610090-227633320 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030319 Approved Tissue enhanced 0 placenta: 2.9 testis: 1.0 -SPATA7 HSD3, LCA3 ENSG00000042317 Spermatogenesis associated 7 14 88384924-88470350 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038082, HPA038083 Supported Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all testis: 102.2 -MED17 CRSP6, CRSP77, DRIP80, TRAP80 ENSG00000042429 Mediator complex subunit 17 11 93784227-93814695 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064236 Approved Vesicles Expressed in all thyroid gland: 26.5 -RETSAT FLJ20296 ENSG00000042445 Retinol saturase (all-trans-retinol 13,14-reductase) 2 85342088-85354620 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007961, HPA046513 Uncertain Approved Nucleoli Expressed in all adipose tissue: 264.9 -CAPG AFCP, MCP ENSG00000042493 Capping protein (actin filament), gelsolin-like 2 85394748-85418432 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018843, HPA019080, HPA019092 Supported Validated Nucleus Expressed in all parathyroid gland: 233.4 -AP2S1 CLAPS2, FBH3, FBHOk, HHC3 ENSG00000042753 Adaptor-related protein complex 2, sigma 1 subunit 19 46838136-46850992 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 114.8 -USH2A RP39, USH2 ENSG00000042781 Usher syndrome 2A (autosomal recessive, mild) 1 215622894-216423396 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 liver: 3.6;testis: 1.0 epididymis: 0.7 -ZPBP SP38, ZPBP1 ENSG00000042813 Zona pellucida binding protein 7 49850421-50121329 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA058673 Supported Tissue enriched 270 testis: 251.1 epididymis: 0.9 -TG AITD3, TGN ENSG00000042832 Thyroglobulin 8 132866958-133134903 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000077, HPA002740, CAB056155 Supported Tissue enriched 1097 thyroid gland: 15544.0 gallbladder: 14.1 -ADAM28 ADAM23, eMDCII, MDC-Lm, MDC-Ls ENSG00000042980 ADAM metallopeptidase domain 28 8 24294040-24359018 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA074034 Approved Plasma membrane
Mitochondria Tissue enhanced 0 epididymis: 428.3 stomach: 104.5 -BARX2 ENSG00000043039 BARX homeobox 2 11 129375940-129452279 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level CAB033311, HPA068414 Supported Supported Nucleoplasm
Cytosol Tissue enhanced 0 esophagus: 104.2;salivary gland: 60.6 fallopian tube: 28.0 -DCUN1D1 DCUN1L1, RP42, SCCRO, SCRO, Tes3 ENSG00000043093 DCN1, defective in cullin neddylation 1, domain containing 1 3 182938074-182985953 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035911 Uncertain Approved Nucleus
Cytosol Tissue enriched 13 testis: 389.4 thyroid gland: 29.4 -JADE2 JADE-2, KIAA0239, PHF15 ENSG00000043143 Jade family PHD finger 2 5 134524312-134583230 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025959, HPA055789 Uncertain Validated Nucleoplasm Expressed in all parathyroid gland: 47.6 -ZIC2 HPE5 ENSG00000043355 Zic family member 2 13 99981772-99986773 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055031 Approved Nuclear bodies Tissue enriched 6 cerebral cortex: 7.4 testis: 1.2 -LCP2 SLP-76, SLP76 ENSG00000043462 Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 5 170246237-170298227 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004574, HPA036396, HPA036397 Supported Expressed in all spleen: 127.7 -TRIT1 FLJ20061, IPT ENSG00000043514 TRNA isopentenyltransferase 1 1 39841022-39883511 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024174 Approved Approved Nucleoplasm
Cytosol Expressed in all endometrium: 24.9 -ADRB1 ADRB1R ENSG00000043591 Adrenoceptor beta 1 10 114044056-114046908 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA067972 Supported Tissue enhanced 0 placenta: 45.2 heart muscle: 11.9 -GUCA2B ENSG00000044012 Guanylate cyclase activator 2B (uroguanylin) 1 42153421-42155824 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 colon: 89.2;small intestine: 151.2 duodenum: 38.6 -CUL7 dJ20C7.5, KIAA0076 ENSG00000044090 Cullin 7 6 43037617-43053945 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015449, HPA030095, HPA030096 Approved Expressed in all fallopian tube: 26.2 -CTNNA1 CAP102 ENSG00000044115 Catenin (cadherin-associated protein), alpha 1, 102kDa 5 138610967-138935034 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021089, HPA046119, HPA063535 Approved Validated Plasma membrane
Cell Junctions Expressed in all parathyroid gland: 215.4 -PHKA2 PHK, PYK ENSG00000044446 Phosphorylase kinase, alpha 2 (liver) X 18892300-18984598 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002912 Approved Approved Nucleoplasm Expressed in all ovary: 18.5 -CNTLN bA340N12.1, C9orf101, C9orf39, FLJ20276 ENSG00000044459 Centlein, centrosomal protein 9 17134982-17503923 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007201, HPA036728, HPA036729 Uncertain Approved Nucleoplasm
Centrosome
Cytosol Mixed endometrium: 11.8 -EPHA3 ETK, ETK1, HEK, HEK4, TYRO4 ENSG00000044524 EPH receptor A3 3 89107524-89482134 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010462 Approved Uncertain Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced 0 prostate: 49.0 gallbladder: 29.9 -HSPA5 BiP, GRP78 ENSG00000044574 Heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 9 125234853-125241330 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005221, HPA038845, HPA038846 Supported Supported Cytosol Expressed in all thyroid gland: 965.5 -DSG2 CDHF5 ENSG00000046604 Desmoglein 2 18 31498043-31549008 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004896, CAB025122 Supported Supported Cell Junctions Tissue enhanced 0 parathyroid gland: 246.8 rectum: 108.5 -GEMIN8 FAM51A1, FLJ20514 ENSG00000046647 Gem (nuclear organelle) associated protein 8 X 14008279-14029893 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028613 Uncertain Supported Nucleoplasm
Cytosol Expressed in all fallopian tube: 31.3 -OFD1 71-7A, CXorf5, JBTS10, RP23 ENSG00000046651 Oral-facial-digital syndrome 1 X 13734745-13769353 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031102, HPA031103, HPA031104 Approved Supported Microtubules Expressed in all parathyroid gland: 34.2 -GPM6B M6B, MGC17150, MGC54284 ENSG00000046653 Glycoprotein M6B X 13771031-13938638 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002913 Approved Tissue enriched 17 cerebral cortex: 838.3 seminal vesicle: 48.9 -MAGEC2 CT10, MAGE-C2, MAGEE1 ENSG00000046774 Melanoma antigen family C2 X 142202345-142205290 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062230 Supported Supported Nucleus
Nucleoli
Cytosol Tissue enriched 368 testis: 36.7 epididymis: 0.0 -PREX2 DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129 ENSG00000046889 Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 8 67952118-68237030 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015234, HPA075956 Approved Approved Endoplasmic reticulum Mixed cerebral cortex: 12.0 -WDR37 KIAA0982 ENSG00000047056 WD repeat domain 37 10 1049538-1132297 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037376, HPA037565 Supported Uncertain Intermediate filaments
Centrosome
Cytosol Expressed in all testis: 36.5 -YTHDC2 DKFZp564A186, FLJ10053, FLJ2194 ENSG00000047188 YTH domain containing 2 5 113513683-113595285 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037364, HPA072678 Approved Approved Nucleoplasm
Nuclear bodies
Cytoplasmic bodies Expressed in all parathyroid gland: 36.4 -CTPS2 ENSG00000047230 CTP synthase 2 X 16588003-16712936 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017437 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 27.6 -ATP6V1H CGI-11, SFD, SFDalpha, SFDbeta, VMA13 ENSG00000047249 ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 8 53715557-53843558 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009532, HPA023421 Approved Approved Actin filaments
Cytosol Expressed in all cerebral cortex: 126.9 -POLR2B RPB2 ENSG00000047315 Polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 4 56977722-57031168 Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037506 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 82.8 -FAM214A FLJ10980, KIAA1370 ENSG00000047346 Family with sequence similarity 214, member A 15 52581317-52709817 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039369, HPA040180 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 56.9 -ARAP2 CENTD1, PARX ENSG00000047365 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 4 35948221-36244509 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035925 Approved Approved Nucleoplasm
Actin filaments
Focal adhesion sites
Cytosol Mixed thyroid gland: 38.8 -TPR ENSG00000047410 Translocated promoter region, nuclear basket protein 1 186311652-186375693 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019661, HPA019663, HPA024336 Supported Validated Nuclear membrane Expressed in all testis: 78.8 -CP ENSG00000047457 Ceruloplasmin (ferroxidase) 3 149162410-149222055 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001834, CAB008591 Supported Tissue enriched 10 liver: 916.4 cervix: 95.6 -KIAA0556 ENSG00000047578 KIAA0556 16 27550133-27780369 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035089, HPA035090 Supported Approved Nuclear speckles
Plasma membrane Tissue enhanced 0 fallopian tube: 47.1 thyroid gland: 26.8 -DTNBP1 BLOC1S8, DBND, Dysbindin, HPS7, My031 ENSG00000047579 Dystrobrevin binding protein 1 6 15522801-15663058 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028053, HPA029615, HPA029616 Supported Supported Microtubules
Midbody Expressed in all lymph node: 33.2 -XK Kx, NA, NAC, X1k, XKR1 ENSG00000047597 X-linked Kx blood group X 37685759-37732130 Blood group antigen proteins, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019036 Approved Approved Nucleoplasm
Vesicles
Mitochondria Mixed rectum: 12.3 -ANO2 C12orf3, TMEM16B ENSG00000047617 Anoctamin 2, calcium activated chloride channel 12 5531869-5946232 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA036276 Supported Nucleoplasm
Plasma membrane Tissue enhanced 0 testis: 17.7 placenta: 5.9 -C12orf4 ENSG00000047621 Chromosome 12 open reading frame 4 12 4487728-4538508 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037871 Uncertain Approved Nuclear bodies Mixed testis: 16.8 -SCML1 ENSG00000047634 Sex comb on midleg-like 1 (Drosophila) X 17737449-17754988 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035270, HPA035271, HPA061397 Supported Approved Nucleus Expressed in all testis: 54.0 -WWC3 BM042, KIAA1280 ENSG00000047644 WWC family member 3 X 10015562-10144478 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039814 Uncertain Approved Actin filaments
Cytosol Expressed in all seminal vesicle: 39.4 -ARHGAP6 rhoGAPX-1 ENSG00000047648 Rho GTPase activating protein 6 X 11137543-11665701 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036779, HPA064390 Approved Tissue enhanced 0 prostate: 43.5;seminal vesicle: 42.8 thyroid gland: 42.2 -FAM184B KIAA1276 ENSG00000047662 Family with sequence similarity 184, member B 4 17629306-17781512 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044119, HPA048458 Uncertain Tissue enhanced 0 cerebral cortex: 2.6;skeletal muscle: 1.4 epididymis: 0.5 -MAP4 ENSG00000047849 Microtubule-associated protein 4 3 47850690-48089272 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038149, HPA038150 Supported Supported Plasma membrane
Microtubules
Cytosol Expressed in all cerebral cortex: 242.6 -GOPC CAL, dJ94G16.2, FIG, GOPC1, PIST ENSG00000047932 Golgi-associated PDZ and coiled-coil motif containing 6 117560269-117602542 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019477, HPA024018 Approved Validated Golgi apparatus
Cytosol Expressed in all parathyroid gland: 47.0 -ROS1 c-ros-1, MCF3, ROS ENSG00000047936 ROS proto-oncogene 1 , receptor tyrosine kinase 6 117288300-117425855 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049098, HPA072424 Uncertain Approved Vesicles Group enriched 18 epididymis: 69.7;lung: 47.3 seminal vesicle: 3.2 -USP28 KIAA1515 ENSG00000048028 Ubiquitin specific peptidase 28 11 113797874-113875570 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006778, HPA006779 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all heart muscle: 39.8 -HDAC9 HD7, HDAC, HDAC7B, KIAA0744, MITR ENSG00000048052 Histone deacetylase 9 7 18086949-19002416 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028926 Uncertain Approved Nucleoplasm Mixed spleen: 25.0 -TSPAN17 FBX23, FBXO23, TM4SF17 ENSG00000048140 Tetraspanin 17 5 176647387-176659054 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030447 Approved Nucleoplasm Expressed in all bone marrow: 34.8 -NOP16 HSPC111, HSPC185, LOC51491 ENSG00000048162 NOP16 nucleolar protein 5 176383938-176388975 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036506, HPA058147 Approved Validated Nucleoli Expressed in all appendix: 26.8 -CC2D2A JBTS9, KIAA1345, MKS6 ENSG00000048342 Coiled-coil and C2 domain containing 2A 4 15469865-15601557 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044124 Approved Tissue enhanced 0 fallopian tube: 53.3 kidney: 20.7 -RRM2B p53R2 ENSG00000048392 Ribonucleotide reductase M2 B (TP53 inducible) 8 102204502-102239118 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006854, HPA028812 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 73.7 -ZNF800 ENSG00000048405 Zinc finger protein 800 7 127346790-127431924 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023090, HPA052194 Approved Supported Nucleoli
Cytosol Expressed in all bone marrow: 48.0 -TNFRSF17 BCM, BCMA, CD269, TNFRSF13A ENSG00000048462 Tumor necrosis factor receptor superfamily, member 17 16 11965107-11968068 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 tonsil: 38.2 lymph node: 31.4 -SNX29 FLJ12363, RUNDC2A ENSG00000048471 Sorting nexin 29 16 11976737-12574289 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008889 Approved Mixed parathyroid gland: 38.9 -LMO3 DAT1, RBTNL2, Rhom-3 ENSG00000048540 LIM domain only 3 (rhombotin-like 2) 12 16548373-16610594 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 191.6 thyroid gland: 67.4 -MRPS10 FLJ10567 ENSG00000048544 Mitochondrial ribosomal protein S10 6 42206801-42217865 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029133, HPA029134 Supported Approved Actin filaments
Mitochondria Expressed in all esophagus: 42.0 -GUCA1A C6orf131, COD3, CORD14, dJ139D8.6, GCAP, GCAP1, GUCA, GUCA1 ENSG00000048545 Guanylate cyclase activator 1A (retina) 6 42155406-42180056 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005561 Supported Approved Uncertain Plasma membrane Tissue enriched 19 testis: 30.0 cerebral cortex: 1.6 -RSF1 HBXAP, p325, RSF-1, XAP8 ENSG00000048649 Remodeling and spacing factor 1 11 77659996-77821017 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022626, HPA046129, HPA057547, HPA064567 Supported Validated Nucleoplasm Expressed in all testis: 44.2 -VPS13D FLJ10619, KIAA0453 ENSG00000048707 Vacuolar protein sorting 13 homolog D (S. cerevisiae) 1 12230067-12512047 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027332, HPA051621 Uncertain Approved Nucleoplasm
Vesicles
Cytosol Expressed in all parathyroid gland: 29.0 -CELF2 BRUNOL3, CUGBP2, Etr-3, NAPOR-2 ENSG00000048740 CUGBP, Elav-like family member 2 10 11005321-11336675 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016395, HPA035813, HPA065098 Supported Uncertain Nucleoplasm
Microtubules
Cytokinetic bridge Mixed cerebral cortex: 76.6 -FAM120A C9orf10, DNAPTP1, KIAA0183, OSSA ENSG00000048828 Family with sequence similarity 120A 9 93451722-93566107 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019734, HPA055800 Approved Validated Cytosol Expressed in all parathyroid gland: 164.2 -R3HDM1 KIAA0029, R3HDM ENSG00000048991 R3H domain containing 1 2 135531455-135725270 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030936 Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 82.5 -COL9A2 EDM2, MED ENSG00000049089 Collagen, type IX, alpha 2 1 40300487-40317816 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056316 Uncertain Approved Nucleus
Vesicles Tissue enhanced 0 parathyroid gland: 52.3 seminal vesicle: 32.1 -KITLG FPH2, Kitl, KL-1, MGF, SCF, SF ENSG00000049130 KIT ligand 12 88492793-88580851 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA070395 Approved Approved Vesicles Mixed lung: 24.2 -ERCC8 CKN1, CSA ENSG00000049167 Excision repair cross-complementation group 8 5 60873831-60945073 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029328 Approved Nuclear speckles Mixed testis: 13.2 -ADAMTS6 ADAM-TS6 ENSG00000049192 ADAM metallopeptidase with thrombospondin type 1 motif, 6 5 65148736-65481920 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043441 Supported Tissue enhanced 0 placenta: 2.7 gallbladder: 2.3 -H6PD GDH ENSG00000049239 Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1 9234775-9271337 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004824, HPA005440 Approved Uncertain Cytosol Expressed in all skin: 42.7 -VAMP3 CEB ENSG00000049245 Vesicle-associated membrane protein 3 1 7771269-7781432 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all lung: 135.4 -PER3 ENSG00000049246 Period circadian clock 3 1 7784320-7845177 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019530 Approved Uncertain Cytosol Mixed thyroid gland: 39.0 -UTS2 PRO1068, U-II, UCN2, UII ENSG00000049247 Urotensin 2 1 7843083-7853512 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA017000 Uncertain Tissue enhanced 0 adrenal gland: 4.0 lymph node: 2.0 -TNFRSF9 4-1BB, CD137, ILA ENSG00000049249 Tumor necrosis factor receptor superfamily, member 9 1 7915894-7943165 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA071425 Approved Nucleoli
Plasma membrane Tissue enhanced 0 lymph node: 11.2;tonsil: 7.4 appendix: 5.3 -EPN3 FLJ20778, MGC129899 ENSG00000049283 Epsin 3 17 50532543-50543750 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055546, HPA063224 Approved Supported Nucleoplasm
Vesicles Mixed stomach: 27.4 -LTBP1 ENSG00000049323 Latent transforming growth factor beta binding protein 1 2 32946972-33399509 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005707, CAB025428 Approved Approved Cytosol Expressed in all cervix: 259.8 -RCN1 FLJ37041, PIG20, Rcal, RCN ENSG00000049449 Reticulocalbin 1, EF-hand calcium binding domain 11 31812391-32105755 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038474, HPA062104 Approved Validated Endoplasmic reticulum Expressed in all epididymis: 464.4 -ELN SVAS, WBS, WS ENSG00000049540 Elastin 7 74027789-74069907 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010750, HPA018111, HPA056941 Supported Approved Plasma membrane Mixed smooth muscle: 124.5 -RFC2 A1, RFC40 ENSG00000049541 Replication factor C (activator 1) 2, 40kDa 7 74231499-74254458 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029493 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all tonsil: 29.3 -ARID1B 6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R ENSG00000049618 AT rich interactive domain 1B (SWI1-like) 6 156777374-157210779 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016511, HPA075291 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 75.6 -CLPTM1L CRR9, FLJ14400 ENSG00000049656 CLPTM1-like 5 1317744-1345099 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014791 Approved Approved Endoplasmic reticulum Expressed in all testis: 54.1 -NEDD4L KIAA0439, NEDD4-2, RSP5 ENSG00000049759 Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 18 58044367-58401540 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024618, HPA064730 Approved Approved Focal adhesion sites Expressed in all prostate: 69.9 -FOXP3 AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID ENSG00000049768 Forkhead box P3 X 49250436-49264826 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB026301, HPA045943 Supported Approved Nucleoplasm Tissue enhanced 0 appendix: 9.0 lymph node: 6.1 -PPP1R3F Hb2E ENSG00000049769 Protein phosphatase 1, regulatory subunit 3F X 49269843-49301461 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000244, HPA000918 Approved Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 27.0 epididymis: 15.0 -HEXB ENSG00000049860 Hexosaminidase B (beta polypeptide) 5 74640023-74722647 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055409, HPA056010 Approved Expressed in all placenta: 437.6 -PTCD2 FLJ12598 ENSG00000049883 Pentatricopeptide repeat domain 2 5 72320367-72368395 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043686 Approved Mixed cerebral cortex: 6.5 -KIAA2022 MRX98, XPN ENSG00000050030 KIAA2022 X 74732849-74925485 Disease related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000407 Uncertain Uncertain Nucleoplasm
Midbody Tissue enhanced 0 cerebral cortex: 5.4;parathyroid gland: 5.2 prostate: 1.8 -JKAMP C14orf100, CDA06, HSPC213, HSPC327, JAMP ENSG00000050130 JNK1/MAPK8-associated membrane protein 14 59484443-59505410 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA031172, HPA071650 Supported Approved Nucleoplasm
Vesicles Expressed in all parathyroid gland: 74.7 -DKK3 REIC, RIG ENSG00000050165 Dickkopf WNT signaling pathway inhibitor 3 11 11963106-12009769 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011868, CAB024949 Approved Approved Vesicles Tissue enhanced 0 cerebral cortex: 374.5;heart muscle: 882.4 cervix: 138.0 -ARHGEF5 GEF5, P60, TIM, TIM1 ENSG00000050327 Rho guanine nucleotide exchange factor (GEF) 5 7 144355288-144380632 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020980, HPA029504, HPA044188, HPA045619, HPA045699 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Mixed thyroid gland: 43.2 -NFE2L3 Nrf3 ENSG00000050344 Nuclear factor, erythroid 2-like 3 7 26152240-26187125 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA055889 Supported Approved Nucleoplasm
Vesicles Tissue enhanced 0 placenta: 51.1 appendix: 14.8 -MCUR1 C6orf79, CCDC90A, FLJ20958 ENSG00000050393 Mitochondrial calcium uniporter regulator 1 6 13786557-13814568 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 26.8 -LIMA1 EPLIN ENSG00000050405 LIM domain and actin binding 1 12 50175788-50283546 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023871, HPA052645 Supported Validated Plasma membrane
Actin filaments
Focal adhesion sites
Cytosol Expressed in all rectum: 146.2 -LETMD1 HCCR1 ENSG00000050426 LETM1 domain containing 1 12 51047962-51060424 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA074361 Supported Nucleoplasm
Mitochondria Expressed in all thyroid gland: 61.5 -SLC4A8 NBC3 ENSG00000050438 Solute carrier family 4, sodium bicarbonate cotransporter, member 8 12 51391317-51515763 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031536 Uncertain Actin filaments Tissue enhanced 0 cerebral cortex: 14.6;testis: 15.4 ovary: 4.2 -LAMC3 DKFZp434E202 ENSG00000050555 Laminin, gamma 3 9 131009082-131094473 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022814 Approved Tissue enhanced 0 placenta: 88.2 testis: 26.2 -PTGER3 EP3 ENSG00000050628 Prostaglandin E receptor 3 (subtype EP3) 1 70852353-71047808 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA010689 Uncertain Group enriched 7 adipose tissue: 58.5;endometrium: 114.7;kidney: 87.6;smooth muscle: 103.9 skin: 14.0 -TNIP3 ABIN-3, FLJ21162, LIND ENSG00000050730 TNFAIP3 interacting protein 3 4 121131408-121227466 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043063 Uncertain Tissue enhanced 0 appendix: 9.0 tonsil: 3.1 -MAPK9 JNK2, p54a, PRKM9, SAPK ENSG00000050748 Mitogen-activated protein kinase 9 5 180233143-180292099 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008910 Approved Expressed in all cerebral cortex: 84.1 -COL23A1 DKFZp434K0621 ENSG00000050767 Collagen, type XXIII, alpha 1 5 178237618-178590555 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067824 Uncertain Tissue enhanced 0 thyroid gland: 57.5 seminal vesicle: 16.1 -BCAR1 CAS, CASS1, Crkas, P130Cas ENSG00000050820 Breast cancer anti-estrogen resistance 1 16 75228187-75268053 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000443, HPA042282 Approved Supported Approved Plasma membrane
Cytosol Mixed spleen: 42.0 -FAM160A2 C11orf56, DKFZP566M1046, FLJ22665, KIAA1759 ENSG00000051009 Family with sequence similarity 160, member A2 11 6211335-6234711 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055994, HPA063987 Approved Approved Mitochondria Expressed in all testis: 42.2 -HERPUD1 HERP, KIAA0025, Mif1, SUP ENSG00000051108 Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 16 56932048-56944863 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037041, CAB037104, HPA040754, HPA041219 Approved Uncertain Plasma membrane
Cytosol Expressed in all prostate: 379.0 -HOMER3 HOMER-3 ENSG00000051128 Homer scaffolding protein 3 19 18929201-18941261 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032656, HPA040999 Supported Supported Plasma membrane
Cytosol
Cytoplasmic bodies Expressed in all spleen: 153.4 -RAD51 BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA ENSG00000051180 RAD51 recombinase 15 40694774-40732339 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010381, HPA039310 Approved Validated Nucleoli
Mitochondria
Cytosol Tissue enhanced 0 testis: 45.1 tonsil: 13.2 -POLQ POLH ENSG00000051341 Polymerase (DNA directed), theta 3 121431427-121546641 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048931, HPA053359 Uncertain Nucleus
Golgi apparatus
Cytosol Mixed testis: 4.0 -PIK3CB PIK3C1 ENSG00000051382 Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 3 138652699-138834938 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB031938, HPA064207 Approved Supported Nucleoplasm
Nucleoli
Midbody Expressed in all thyroid gland: 88.7 -CYBA p22-PHOX ENSG00000051523 Cytochrome b-245, alpha polypeptide 16 88643283-88651152 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009492 Supported Expressed in all spleen: 476.3 -THOC3 MGC5469, TEX1 ENSG00000051596 THO complex 3 5 175917873-176034680 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042764, HPA044009, HPA045071 Approved Validated Nucleoplasm Expressed in all epididymis: 76.5 -HEBP2 C6orf34, SOUL ENSG00000051620 Heme binding protein 2 6 138403531-138422197 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016928 Approved Expressed in all adipose tissue: 113.9 -MPHOSPH9 MPP9 ENSG00000051825 M-phase phosphoprotein 9 12 123152320-123244014 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037485 Approved Uncertain Nucleus
Plasma membrane
Cytosol Mixed testis: 22.5 -PLEKHA5 FLJ10667, KIAA1686, PEPP2 ENSG00000052126 Pleckstrin homology domain containing, family A member 5 12 19129752-19376400 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035923, HPA035924, HPA041455 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 54.4 -PRSS8 ENSG00000052344 Protease, serine, 8 16 31131433-31135762 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030436, HPA063533 Uncertain Uncertain Cytosol Mixed small intestine: 168.0 -SIKE1 FLJ21168, SIKE ENSG00000052723 Suppressor of IKBKE 1 1 114769479-114780685 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024177, HPA025726 Supported Approved Vesicles
Focal adhesion sites Expressed in all thyroid gland: 19.3 -RRP12 KIAA0690 ENSG00000052749 Ribosomal RNA processing 12 homolog 10 97356358-97426076 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049945 Supported Nucleoli Expressed in all bone marrow: 58.3 -FNIP2 FNIPL, KIAA1450, MAPO1 ENSG00000052795 Folliculin interacting protein 2 4 158769138-158908049 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042779 Approved Expressed in all kidney: 50.8 -MSMO1 DESP4, ERG25, SC4MOL ENSG00000052802 Methylsterol monooxygenase 1 4 165327623-165343160 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056127 Approved Expressed in all liver: 296.4 -TTC17 FLJ10890 ENSG00000052841 Tetratricopeptide repeat domain 17 11 43358932-43494933 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038508 Approved Supported Plasma membrane
Cytosol Expressed in all thyroid gland: 61.6 -ALX4 FPP, KIAA1788, PFM, PFM2 ENSG00000052850 ALX homeobox 4 11 44260444-44310166 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA001903 Supported Nucleoplasm Tissue enhanced 0 breast: 2.2 testis: 1.0 -FSTL4 KIAA1061 ENSG00000053108 Follistatin-like 4 5 133196455-133612564 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045920 Uncertain Approved Mitochondria Tissue enhanced 0 cerebral cortex: 9.6 urinary bladder: 7.6 -FOXN3 C14orf116, CHES1 ENSG00000053254 Forkhead box N3 14 89124871-89619149 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059209 Approved Approved Nucleus
Plasma membrane
Cytokinetic bridge Expressed in all parathyroid gland: 109.4 -METTL24 C6orf186, dJ71D21.2 ENSG00000053328 Methyltransferase like 24 6 110245928-110358272 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037441, HPA037442 Uncertain Tissue enhanced 0 smooth muscle: 20.2 endometrium: 12.7 -AKR7A2 AFAR ENSG00000053371 Aldo-keto reductase family 7, member A2 1 19303965-19312146 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032587, CAB032841, HPA064638 Supported Supported Cytosol Expressed in all duodenum: 84.1 -MRTO4 C1orf33, dJ657E11.4, MRT4 ENSG00000053372 MRT4 homolog, ribosome maturation factor 1 19251539-19260128 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026446 Approved Approved Nucleus
Nuclear membrane
Nucleoli Expressed in all fallopian tube: 26.0 -NNAT Peg5 ENSG00000053438 Neuronatin 20 37521215-37523693 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 5 cerebral cortex: 158.1;placenta: 148.0 adipose tissue: 28.1 -USE1 D12, MDS032, p31, SLT1 ENSG00000053501 Unconventional SNARE in the ER 1 homolog (S. cerevisiae) 19 17215346-17219829 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026851, HPA047562 Approved Expressed in all cerebral cortex: 42.1 -MCF2L2 ARHGEF22, KIAA0861 ENSG00000053524 MCF.2 cell line derived transforming sequence-like 2 3 183178043-183428778 Disease related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA038946, HPA038947 Uncertain Approved Plasma membrane
Cytosol Group enriched 8 adrenal gland: 10.3;cerebral cortex: 17.1;parathyroid gland: 7.4;spleen: 3.5;testis: 4.6 prostate: 1.0 -NRIP2 DKFZP761G1913 ENSG00000053702 Nuclear receptor interacting protein 2 12 2825348-2835544 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039197, HPA039860 Supported Mixed endometrium: 14.0 -LAMA3 BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa ENSG00000053747 Laminin, alpha 3 18 23689443-23955066 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009309, CAB010757 Uncertain Approved Endoplasmic reticulum
Vesicles
Cytosol Mixed placenta: 30.5 -AP5M1 C14orf108, FLJ10813, mu5, MuD, MUDENG ENSG00000053770 Adaptor-related protein complex 5, mu 1 subunit 14 57268909-57298742 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055768, HPA057098 Approved Expressed in all parathyroid gland: 42.3 -ANAPC4 APC4 ENSG00000053900 Anaphase promoting complex subunit 4 4 25377213-25418498 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032519, HPA038395, HPA038396 Approved Approved Intermediate filaments Expressed in all fallopian tube: 54.6 -KCNQ1 JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1 ENSG00000053918 Potassium channel, voltage gated KQT-like subfamily Q, member 1 11 2444684-2849109 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018656, HPA048553 Supported Tissue enhanced 0 adrenal gland: 134.2;thyroid gland: 102.8 seminal vesicle: 60.3 -TRAPPC3 BET3 ENSG00000054116 Trafficking protein particle complex 3 1 36136570-36156053 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028408 Approved Approved Golgi apparatus
Cytosol Expressed in all thyroid gland: 101.6 -THRAP3 TRAP150 ENSG00000054118 Thyroid hormone receptor associated protein 3 1 36224416-36305357 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012041, CAB017472, HPA063765 Supported Validated Nuclear speckles Expressed in all parathyroid gland: 97.5 -PHPT1 bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14 ENSG00000054148 Phosphohistidine phosphatase 1 9 136848724-136851027 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013584, HPA020952 Approved Approved Nuclear bodies
Cytosol Expressed in all skeletal muscle: 71.6 -ENTPD2 CD39L1, NTPDase-2 ENSG00000054179 Ectonucleoside triphosphate diphosphohydrolase 2 9 137048098-137054045 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017676 Approved Mixed duodenum: 12.6 -LY75 CD205, CLEC13B, DEC-205 ENSG00000054219 Lymphocyte antigen 75 2 159803355-159904749 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001450, HPA049108, HPA054073 Supported Approved Golgi apparatus Mixed lymph node: 36.0 -ARID4B BCAA, BRCAA1, RBP1L1, SAP180 ENSG00000054267 AT rich interactive domain 4B (RBP1-like) 1 235131634-235328219 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027333, HPA053692 Approved Approved Nucleoplasm
Vesicles Expressed in all testis: 30.3 -OPN3 ECPN, encephalopsin, ERO, NMO-1, PPP1R116 ENSG00000054277 Opsin 3 1 241590102-241677376 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB013682, HPA064443 Uncertain Approved Nucleoplasm Tissue enhanced 0 placenta: 26.8 lung: 12.7 -SDCCAG8 BBS16, CCCAP, NPHP10, NY-CO-8, SLSN7 ENSG00000054282 Serologically defined colon cancer antigen 8 1 243256034-243500092 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025737, HPA044477, HPA072495 Approved Validated Centrosome Expressed in all thyroid gland: 23.9 -PTPRN IA-2 ENSG00000054356 Protein tyrosine phosphatase, receptor type, N 2 219289623-219309648 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007152, HPA007179 Supported Approved Endoplasmic reticulum Tissue enriched 5 cerebral cortex: 183.6 adrenal gland: 35.2 -HHAT FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn ENSG00000054392 Hedgehog acyltransferase 1 210328252-210676296 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016462 Approved Approved Golgi apparatus Mixed thyroid gland: 7.8 -KIF1B CMT2, CMT2A, HMSNII, KIAA0591, KLP ENSG00000054523 Kinesin family member 1B 1 10210805-10381603 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB015177 Approved Uncertain Nucleoli fibrillar center
Cytosol Expressed in all cerebral cortex: 105.7 -FOXC1 ARA, FKHL7, FREAC3, IGDA, IHG1, IRID1 ENSG00000054598 Forkhead box C1 6 1609972-1613897 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040670 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 salivary gland: 66.5 kidney: 21.6 -TBC1D22A C22orf4 ENSG00000054611 TBC1 domain family, member 22A 22 46762617-47175699 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001173 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all spleen: 22.4 -SYNE2 DKFZP434H2235, KIAA1011, Nesp2, Nesprin-2, NUA, NUANCE, SYNE-2 ENSG00000054654 Spectrin repeat containing, nuclear envelope 2 14 63852983-64226433 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003435, HPA050204 Supported Validated Nuclear membrane Expressed in all parathyroid gland: 187.4 -PLEKHH1 KIAA1200 ENSG00000054690 Pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 14 67533301-67589612 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047707, HPA051964 Uncertain Approved Centrosome Tissue enhanced 0 cerebral cortex: 43.4;thyroid gland: 51.0 parathyroid gland: 15.4 -ATP9A ATPIIA, KIAA0611 ENSG00000054793 ATPase, class II, type 9A 20 51596514-51768634 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020699, HPA035630 Approved Expressed in all cerebral cortex: 156.2 -SPO11 CT35, SPATA43, TOPVIA ENSG00000054796 SPO11 meiotic protein covalently bound to DSB 20 57329759-57343994 Plasma proteins, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 153 testis: 15.3 epididymis: 0.0 -CBLN4 CBLNL1, dJ885A10.1 ENSG00000054803 Cerebellin 4 precursor 20 55997440-56005472 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056335, HPA074497 Supported Uncertain Endoplasmic reticulum Tissue enhanced 0 adrenal gland: 24.7;cerebral cortex: 15.7;epididymis: 11.0 fallopian tube: 6.7 -CHRDL2 BNF1 ENSG00000054938 Chordin-like 2 11 74696429-74731385 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021771 Uncertain Uncertain Mitochondria Group enriched 9 appendix: 162.3;endometrium: 128.0;gallbladder: 169.0;smooth muscle: 181.2;urinary bladder: 45.0 cervix: 14.5 -FAM168A KIAA0280, TCRP1 ENSG00000054965 Family with sequence similarity 168, member A 11 73400487-73598189 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037580 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 104.7 -RELT FLJ14993, TNFRSF19L ENSG00000054967 RELT tumor necrosis factor receptor 11 73376264-73397474 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062824, HPA071518 Supported Nucleus Tissue enriched 5 bone marrow: 96.0 spleen: 17.5 -GALC ENSG00000054983 Galactosylceramidase 14 87837820-87993665 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022196 Approved Expressed in all testis: 45.4 -NOP58 HSPC120, NOP5 ENSG00000055044 NOP58 ribonucleoprotein 2 202265716-202303666 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018472, HPA021062 Supported Validated Nucleus
Nucleoli fibrillar center Expressed in all lymph node: 70.2 -SZRD1 C1orf144, DKFZp566C0424 ENSG00000055070 SUZ RNA binding domain containing 1 1 16352575-16398145 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024221 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 90.0 -KCNH2 erg1, HERG, Kv11.1, LQT2 ENSG00000055118 Potassium channel, voltage gated eag related subfamily H, member 2 7 150944961-150978315 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 24.1;testis: 27.4 parathyroid gland: 12.9 -CUL1 ENSG00000055130 Cullin 1 7 148697914-148801036 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002676, HPA064584 Supported Supported Nucleus
Nucleoli Expressed in all testis: 184.4 -FAM114A2 133K02, C5orf3 ENSG00000055147 Family with sequence similarity 114, member A2 5 153990128-154038936 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035869, HPA035870 Approved Approved Vesicles Expressed in all testis: 68.6 -CYFIP2 PIR121 ENSG00000055163 Cytoplasmic FMR1 interacting protein 2 5 157266079-157395595 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB055519, HPA068106, HPA071459 Uncertain Approved Endoplasmic reticulum
Plasma membrane
Cytosol Expressed in all kidney: 165.0 -TAB2 KIAA0733, MAP3K7IP2 ENSG00000055208 TGF-beta activated kinase 1/MAP3K7 binding protein 2 6 149218641-149411613 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071215 Supported Cytosol Expressed in all parathyroid gland: 66.5 -GINM1 C6orf72, dJ12G14.2 ENSG00000055211 Glycoprotein integral membrane 1 6 149566294-149591748 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA017210, HPA041679 Approved Approved Nucleoli fibrillar center
Plasma membrane Expressed in all thyroid gland: 118.1 -EIF2AK2 EIF2AK1, PKR, PPP1R83, PRKR ENSG00000055332 Eukaryotic translation initiation factor 2-alpha kinase 2 2 37099210-37157065 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003845, HPA019795, HPA063893 Approved Validated Cytosol Expressed in all parathyroid gland: 25.1 -USP36 FLJ12851, KIAA1453 ENSG00000055483 Ubiquitin specific peptidase 36 17 78787381-78841441 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012082, HPA012395, HPA052860 Uncertain Approved Validated Nucleoli
Nuclear speckles Expressed in all skin: 38.4 -KMT2C HALR, KIAA1506, MLL3 ENSG00000055609 Lysine (K)-specific methyltransferase 2C 7 152134922-152436005 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA074736 Supported Nucleoplasm Expressed in all skin: 25.8 -MCOLN3 FLJ11006, TRP-ML3, TRPML3 ENSG00000055732 Mucolipin 3 1 85018082-85048499 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA018106, HPA062137 Approved Approved Nucleoli
Cytosol Tissue enhanced 0 adrenal gland: 57.9;parathyroid gland: 42.1 epididymis: 17.3 -CCDC85A KIAA1912 ENSG00000055813 Coiled-coil domain containing 85A 2 56184123-56386173 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043106, HPA057020 Uncertain Tissue enhanced 0 cerebral cortex: 21.1 thyroid gland: 15.8 -PUM2 KIAA0235, PUMH2 ENSG00000055917 Pumilio RNA-binding family member 2 2 20248691-20352234 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030316, HPA049670 Approved Validated Cytosol Expressed in all thyroid gland: 97.7 -MRPL43 bMRP36a ENSG00000055950 Mitochondrial ribosomal protein L43 10 100969458-100987515 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA073022 Approved Nucleoplasm
Mitochondria Expressed in all thyroid gland: 57.8 -ITIH4 H4P, IHRP, ITIHL1 ENSG00000055955 Inter-alpha-trypsin inhibitor heavy chain family, member 4 3 52812975-52831479 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001835, HPA003948, CAB072872 Supported Approved Vesicles Tissue enriched 71 liver: 983.2 skeletal muscle: 13.8 -ITIH1 H1P, IATIH, ITIH ENSG00000055957 Inter-alpha-trypsin inhibitor heavy chain 1 3 52777592-52792068 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041639, HPA042049 Approved Approved Vesicles Tissue enriched 449 liver: 785.8 spleen: 1.7 -C4orf27 FLJ20534 ENSG00000056050 Chromosome 4 open reading frame 27 4 169729465-169757953 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043467 Uncertain Approved Microtubules
Cytokinetic bridge
Cytosol Expressed in all endometrium: 38.3 -ZFR SPG71, ZFR1 ENSG00000056097 Zinc finger RNA binding protein 5 32354350-32444761 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016666 Supported Approved Nucleoplasm Expressed in all cerebral cortex: 77.7 -ZNF280C FLJ20095, SUHW3, ZNF633 ENSG00000056277 Zinc finger protein 280C X 130202711-130268899 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051494, HPA055788 Uncertain Approved Nucleus
Nucleoli fibrillar center Tissue enhanced 0 testis: 17.4 epididymis: 6.2 -NPFFR2 GPR74, NPFF2, NPGPR ENSG00000056291 Neuropeptide FF receptor 2 4 72031804-72148067 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA026825 Approved Plasma membrane
Actin filaments Tissue enhanced 0 placenta: 2.3;seminal vesicle: 4.5 epididymis: 1.1 -PHF21B BHC80L, FLJ34161, PHF4 ENSG00000056487 PHD finger protein 21B 22 44881162-45009999 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA053834 Uncertain Uncertain Nucleus
Nucleoli fibrillar center Tissue enhanced 0 cerebral cortex: 6.7;cervix, uterine: 5.5;testis: 6.4 endometrium: 5.3 -TRAF1 EBI6 ENSG00000056558 TNF receptor-associated factor 1 9 120902393-120929173 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001852, CAB009593 Approved Approved Nucleoplasm Tissue enhanced 0 lymph node: 38.1 appendix: 28.1 -RC3H2 FLJ20301, FLJ20713, MNAB, RNF164 ENSG00000056586 Ring finger and CCCH-type domains 2 9 122844556-122905341 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042863 Approved Supported Cytosol Expressed in all parathyroid gland: 25.0 -IL17RB CRL4, EVI27, IL17BR, IL17RH1 ENSG00000056736 Interleukin 17 receptor B 3 53846580-53865800 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA005482 Supported Tissue enhanced 0 kidney: 62.4 cervix: 32.2 -TRAF3IP2 ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZP586G0522 ENSG00000056972 TRAF3 interacting protein 2 6 111556454-111606278 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036352 Approved Approved Golgi apparatus
Vesicles Expressed in all fallopian tube: 49.4 -GYG2 GN-2 ENSG00000056998 Glycogenin 2 X 2828788-2882818 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005495, HPA064686 Approved Approved Nucleus
Nucleoli
Cytosol Tissue enriched 13 adipose tissue: 161.7 breast: 12.5 -DCBLD2 CLCP1, ESDN ENSG00000057019 Discoidin, CUB and LCCL domain containing 2 3 98795941-98901689 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016909 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Mixed testis: 44.8 -SERPINB3 HsT1196, SCC, SCCA1, T4-A ENSG00000057149 Serpin peptidase inhibitor, clade B (ovalbumin), member 3 18 63637719-63661963 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018772, CAB036006, CAB036007, HPA048341, HPA049988, HPA055992 Supported Approved Plasma membrane
Cytosol Group enriched 6 cervix, uterine: 297.6;esophagus: 851.2 urinary bladder: 90.5 -SOAT1 ACAT, SOAT, STAT ENSG00000057252 Sterol O-acyltransferase 1 1 179293714-179358680 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009533, HPA047171 Supported Validated Endoplasmic reticulum Tissue enhanced 0 adrenal gland: 219.3 prostate: 44.0 -PKP2 ENSG00000057294 Plakophilin 2 12 32790745-32896840 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014314, HPA056908 Approved Validated Nucleoplasm
Cell Junctions Tissue enhanced 0 fallopian tube: 113.1;heart muscle: 114.5 parathyroid gland: 50.2 -MSH4 ENSG00000057468 MutS homolog 4 1 75796882-75913238 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 6 epididymis: 2.3;testis: 7.7 spleen: 0.7 -F7 ENSG00000057593 Coagulation factor VII (serum prothrombin conversion accelerator) 13 113105788-113120681 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 44 liver: 65.2 testis: 1.4 -GDI2 RABGDIB ENSG00000057608 GDP dissociation inhibitor 2 10 5765223-5842132 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049290, HPA057668 Supported Expressed in all lymph node: 244.2 -PRDM1 BLIMP1, PRDI-BF1 ENSG00000057657 PR domain containing 1, with ZNF domain 6 106086320-106109939 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030033 Approved Approved Nucleus
Nucleoli Tissue enhanced 0 esophagus: 61.3 endometrium: 30.1 -ATG5 APG5, APG5L, ASP, hAPG5 ENSG00000057663 Autophagy related 5 6 106184476-106325820 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034432, CAB037309, HPA042973 Supported Approved Centrosome Expressed in all thyroid gland: 32.1 -TMCC3 KIAA1145 ENSG00000057704 Transmembrane and coiled-coil domain family 3 12 94567124-94650562 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014272 Approved Approved Cytosol Mixed placenta: 25.5 -PITHD1 C1orf128, HT014, TXNL1CL ENSG00000057757 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 1 23778405-23788232 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016936 Uncertain Expressed in all parathyroid gland: 205.1 -MTA3 KIAA1266 ENSG00000057935 Metastasis associated 1 family, member 3 2 42494569-42756947 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039433 Approved Supported Nucleus
Vesicles Expressed in all testis: 52.2 -USP13 IsoT-3 ENSG00000058056 Ubiquitin specific peptidase 13 (isopeptidase T-3) 3 179652755-179789401 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004827 Uncertain Approved Nucleoplasm
Cytosol Expressed in all skeletal muscle: 52.2 -ATP11B ATPIF, ATPIR, KIAA0956 ENSG00000058063 ATPase, class VI, type 11B 3 182793500-182921635 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036237, HPA036238 Uncertain Approved Microtubule organizing center
Cytosol Expressed in all testis: 57.7 -LAMC2 BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa ENSG00000058085 Laminin, gamma 2 1 183186238-183244900 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004257, HPA024638, CAB078165 Approved Approved Cytosol Mixed fallopian tube: 57.2 -CDK14 PFTAIRE1, PFTK1 ENSG00000058091 Cyclin-dependent kinase 14 7 90466424-91210590 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015267 Approved Supported Nucleus
Cytosol Expressed in all cerebral cortex: 56.8 -SEC61A1 ENSG00000058262 Sec61 translocon alpha 1 subunit 3 128051641-128071683 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022076 Supported Endoplasmic reticulum Expressed in all cervix: 217.0 -PPP1R12A M130, MBS, MYPT1 ENSG00000058272 Protein phosphatase 1, regulatory subunit 12A 12 79773563-79935460 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041296, HPA071956 Validated Actin filaments
Cytosol Expressed in all smooth muscle: 120.1 -RASGRF1 CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187 ENSG00000058335 Ras protein-specific guanine nucleotide-releasing factor 1 15 78959947-79090773 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010413, HPA041965 Approved Supported Golgi apparatus Group enriched 14 cerebral cortex: 30.6;lung: 11.7 lymph node: 1.5 -CAMK2B CAM2, CAMK2, CAMKB ENSG00000058404 Calcium/calmodulin-dependent protein kinase II beta 7 44217150-44334577 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006849, HPA026307, HPA051783, HPA051785, HPA053973 Supported Supported Uncertain Plasma membrane
Cell Junctions Tissue enhanced 0 cerebral cortex: 214.7 skeletal muscle: 46.1 -CROCC ROLT, rootletin ENSG00000058453 Ciliary rootlet coiled-coil, rootletin 1 16740273-16972979 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021191, HPA021762 Supported Supported Plasma membrane
Centrosome Mixed skin: 11.7 -POLR3E FLJ10509, RPC5, SIN ENSG00000058600 Polymerase (RNA) III (DNA directed) polypeptide E (80kD) 16 22297375-22335103 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041419, HPA041477 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 17.5 -ATP2B4 ATP2B2, MXRA1, PMCA4 ENSG00000058668 ATPase, Ca++ transporting, plasma membrane 4 1 203626561-203744081 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016118, HPA040431 Supported Supported Plasma membrane Expressed in all smooth muscle: 251.3 -ZC3H11A KIAA0663, ZC3HDC11A ENSG00000058673 Zinc finger CCCH-type containing 11A 1 203795654-203854124 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026439, HPA028490, HPA028526 Approved Approved Nuclear speckles Expressed in all parathyroid gland: 113.9 -RIOK2 FLJ11159 ENSG00000058729 RIO kinase 2 5 97160867-97183260 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005681 Uncertain Approved Plasma membrane
Cytosol Expressed in all testis: 22.0 -YIPF1 DJ167A19.1, FinGER1 ENSG00000058799 Yip1 domain family, member 1 1 53851719-53889834 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014716 Approved Approved Nucleoplasm Expressed in all thyroid gland: 42.1 -NDC1 FLJ10407, NET3, TMEM48 ENSG00000058804 NDC1 transmembrane nucleoporin 1 53765460-53838860 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069751, HPA070882 Approved Supported Nuclear membrane
Plasma membrane
Actin filaments Mixed lymph node: 16.6 -DGKG DAGK3 ENSG00000058866 Diacylglycerol kinase, gamma 90kDa 3 186105668-186362237 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036577 Approved Approved Vesicles
Plasma membrane Tissue enhanced 0 cerebral cortex: 21.3 placenta: 11.1 -FLYWCH1 DKFZp761A132 ENSG00000059122 FLYWCH-type zinc finger 1 16 2911937-2951208 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040753, HPA041001 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all parathyroid gland: 30.0 -UNKL C16orf28, FLJ23360, ZC3H5L, ZC3HDC5L ENSG00000059145 Unkempt family zinc finger-like 16 1363205-1414751 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055801, HPA073949 Approved Approved Cytosol Mixed endometrium: 9.1 -TBXAS1 CYP5, CYP5A1, THAS, TS, TXAS, TXS ENSG00000059377 Thromboxane A synthase 1 (platelet) 7 139777051-140020325 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031257, HPA031258, HPA031259 Supported Supported Vesicles Mixed spleen: 57.1 -PARP12 FLJ22693, PARP-12, ZC3H1, ZC3HDC1 ENSG00000059378 Poly (ADP-ribose) polymerase family, member 12 7 140023744-140063721 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003584, HPA063872 Approved Approved Nucleus Mixed skin: 13.8 -ALDH18A1 GSAS, P5CS, PYCS ENSG00000059573 Aldehyde dehydrogenase 18 family, member A1 10 95605929-95656706 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008333, HPA012604 Approved Validated Mitochondria Expressed in all duodenum: 92.0 -TARBP1 TRM3, TRP-185 ENSG00000059588 TAR (HIV-1) RNA binding protein 1 1 234391313-234479103 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB020810, HPA024632 Uncertain Approved Nuclear speckles Expressed in all parathyroid gland: 15.8 -GATB PET112, PET112L ENSG00000059691 Glutamyl-tRNA(Gln) amidotransferase, subunit B 4 151670504-151761023 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042610 Uncertain Supported Mitochondria Mixed kidney: 22.2 -MXD1 bHLHc58, MAD, MAD1 ENSG00000059728 MAX dimerization protein 1 2 69897688-69942945 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA001599 Supported Uncertain Nucleoplasm
Mitochondria
Cytosol Tissue enhanced 0 bone marrow: 114.0;esophagus: 102.3 appendix: 57.5 -CDK17 PCTAIRE2, PCTK2 ENSG00000059758 Cyclin-dependent kinase 17 12 96278261-96400560 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015325 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 72.0 -DNAJC25 bA16L21.2.1 ENSG00000059769 DnaJ (Hsp40) homolog, subfamily C , member 25 9 111631352-111654351 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019122 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 liver: 16.7 parathyroid gland: 7.8 -SLC2A3 GLUT3 ENSG00000059804 Solute carrier family 2 (facilitated glucose transporter), member 3 12 7919230-7936275 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002763, HPA006539 Approved Approved Plasma membrane Tissue enhanced 0 bone marrow: 271.6 placenta: 137.6 -PSD EFA6, EFA6A, KIAA2011, PSD1, TYL ENSG00000059915 Pleckstrin and Sec7 domain containing 10 102402617-102421539 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059237 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 77.8 endometrium: 25.4 -CTDP1 FCP1 ENSG00000060069 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 18 79679801-79756623 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032641, HPA040394 Supported Supported Nuclear speckles
Actin filaments Expressed in all testis: 19.6 -YBX3 CSDA, CSDA1, dbpA, ZONAB ENSG00000060138 Y box binding protein 3 12 10699089-10723312 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034838 Approved Supported Cytosol Expressed in all skeletal muscle: 1301.2 -STYK1 DKFZp761P1010, NOK, SuRTK106 ENSG00000060140 Serine/threonine/tyrosine kinase 1 12 10618939-10674318 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA040468, HPA048569 Uncertain Approved Nucleus
Plasma membrane Mixed rectum: 17.8 -WNK1 HSAN2, HSN2, PPP1R167, PRKWNK1 ENSG00000060237 WNK lysine deficient protein kinase 1 12 752593-911452 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046541, HPA059157 Supported Supported Cytosol Expressed in all esophagus: 92.7 -CCAR1 CARP-1, CARP1, FLJ10590 ENSG00000060339 Cell division cycle and apoptosis regulator 1 10 68721012-68792377 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007856, HPA048513 Supported Supported Nucleoplasm
Golgi apparatus Expressed in all lymph node: 35.2 -OGFR 7-60 ENSG00000060491 Opioid growth factor receptor 20 62804835-62814000 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017899 Supported Approved Nucleoplasm Expressed in all spleen: 53.6 -GNA15 GNA16 ENSG00000060558 Guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 19 3136193-3163769 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043113 Approved Tissue enhanced 0 bone marrow: 48.8;esophagus: 61.5 skin: 25.9 -CREB3L3 CREB-H ENSG00000060566 CAMP responsive element binding protein 3-like 3 19 4153601-4173054 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040671, HPA056228 Supported Group enriched 104 duodenum: 248.3;liver: 61.3;small intestine: 284.6 colon: 1.9 -PIGV FLJ20477 ENSG00000060642 Phosphatidylinositol glycan anchor biosynthesis, class V 1 26787472-26798398 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054181 Approved Endoplasmic reticulum
Cytosol Expressed in all testis: 83.5 -PTPRU FMI, hPTP-J, PCP-2, PTP, PTPRO ENSG00000060656 Protein tyrosine phosphatase, receptor type, U 1 29236516-29326813 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB011476, HPA039832 Approved Mixed cervix: 27.8 -SNRNP40 HPRP8BP, PRP8BP, PRPF8BP, SPF38, WDR57 ENSG00000060688 Small nuclear ribonucleoprotein 40kDa (U5) 1 31259568-31296782 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026527, HPA027345 Supported Supported Nuclear speckles Expressed in all lymph node: 41.5 -RIMBP2 KIAA0318, MGC15831, PPP1R133, RBP2, RIM-BP2 ENSG00000060709 RIMS binding protein 2 12 130396137-130716281 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041494 Uncertain Nucleus
Golgi apparatus Tissue enhanced 0 parathyroid gland: 94.1 cerebral cortex: 25.7 -COL11A1 CO11A1, COLL6, STL2 ENSG00000060718 Collagen, type XI, alpha 1 1 102876467-103108496 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058335 Supported Endoplasmic reticulum Tissue enriched 6 placenta: 27.9 gallbladder: 4.7 -QSER1 FLJ21924 ENSG00000060749 Glutamine and serine rich 1 11 32893178-32993316 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005682 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 17.6 -MPC1 BRP44L, CGI-129, dJ68L15.3 ENSG00000060762 Mitochondrial pyruvate carrier 1 6 166364919-166383013 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045119, HPA055790 Supported Validated Mitochondria Expressed in all heart muscle: 409.2 -ACAA1 ENSG00000060971 Acetyl-CoA acyltransferase 1 3 38103129-38137242 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006764, HPA007244 Supported Validated Peroxisomes Expressed in all liver: 327.6 -BCAT1 BCT1 ENSG00000060982 Branched chain amino-acid transaminase 1, cytosolic 12 24810022-24949459 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048592 Uncertain Mixed placenta: 21.3 -HDAC7 DKFZP586J0917, HDAC7A ENSG00000061273 Histone deacetylase 7 12 47782722-47833132 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004775 Supported Cytosol Expressed in all parathyroid gland: 42.9 -LZTS1 FEZ1 ENSG00000061337 Leucine zipper, putative tumor suppressor 1 8 20246165-20303963 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006294, HPA022046 Approved Approved Nucleoli
Plasma membrane Tissue enriched 10 parathyroid gland: 123.3 cerebral cortex: 12.4 -PRDM6 ENSG00000061455 PR domain containing 6 5 123089121-123194266 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030322, HPA030324 Uncertain Uncertain Nucleoplasm Tissue enhanced 0 gallbladder: 5.2;placenta: 5.9 lung: 4.0 -WNT8A WNT8D ENSG00000061492 Wingless-type MMTV integration site family, member 8A 5 138083892-138092365 Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level HPA038539 Uncertain Uncertain Plasma membrane
Cytosol Not detected testis: 0.7 -SPAG4 CT127, SUN4 ENSG00000061656 Sperm associated antigen 4 20 35615892-35621049 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048393, HPA061789 Approved Mixed testis: 22.6 -NCKAP1 HEM2, Nap1, NAP125 ENSG00000061676 NCK-associated protein 1 2 182909115-183038858 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020449 Approved Approved Cytosol Mixed cerebral cortex: 145.6 -MRPS35 MDS023, MRPS28 ENSG00000061794 Mitochondrial ribosomal protein S35 12 27710773-27756295 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038513 Supported Approved Mitochondria
Cytosol Expressed in all kidney: 78.1 -GUCY1B3 GC-S-beta-1, GC-SB3, GUC1B3 ENSG00000061918 Guanylate cyclase 1, soluble, beta 3 4 155758992-155807591 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010890, HPA020870 Approved Approved Cytosol Expressed in all parathyroid gland: 174.2 -SFSWAP SFRS8, SWAP ENSG00000061936 Splicing factor, suppressor of white-apricot family 12 131711081-131799737 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039362, HPA040063 Approved Approved Nucleus
Plasma membrane
Cytosol Expressed in all skin: 18.1 -TNK2 ACK, ACK1, p21cdc42Hs ENSG00000061938 Tyrosine kinase, non-receptor, 2 3 195863364-195911945 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041954 Approved Approved Cytosol Expressed in all cerebral cortex: 109.8 -MON2 KIAA1040 ENSG00000061987 MON2 homolog, regulator of endosome-to-Golgi trafficking 12 62466817-62600479 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038697, HPA057607 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center Expressed in all parathyroid gland: 33.5 -CDH3 CDHP, PCAD ENSG00000062038 Cadherin 3, type 1, P-cadherin (placental) 16 68636189-68722616 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001767, CAB002487 Supported Uncertain Cell Junctions
Cytosol Tissue enhanced 0 skin: 32.0 ovary: 26.9 -ARSF ENSG00000062096 Arylsulfatase F X 3041471-3112726 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000549 Uncertain Cytosol Group enriched 6 adrenal gland: 4.0;cerebral cortex: 2.1;epididymis: 2.1;esophagus: 2.3;kidney: 8.0;skin: 6.7 urinary bladder: 0.6 -GPBP1 DKFZp761C169, vasculin ENSG00000062194 GC-rich promoter binding protein 1 5 57173948-57264679 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037773 Approved Approved Vesicles
Plasma membrane
Cytosol Expressed in all testis: 138.1 -DGAT2 ENSG00000062282 Diacylglycerol O-acyltransferase 2 11 75759512-75801535 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adipose tissue: 492.5;liver: 170.3 skin: 116.3 -ZNF112 ZFP112, ZNF228 ENSG00000062370 Zinc finger protein 112 19 44326555-44367217 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023856 Approved Approved Centrosome Mixed testis: 13.7 -CS ENSG00000062485 Citrate synthase 12 56271699-56300392 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754 Supported Validated Mitochondria Expressed in all heart muscle: 203.7 -LTK TYK1 ENSG00000062524 Leukocyte receptor tyrosine kinase 15 41503638-41513887 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059545 Uncertain Approved Vesicles Mixed placenta: 15.1 -MRPS24 HSPC335, MRP-S24 ENSG00000062582 Mitochondrial ribosomal protein S24 7 43866558-43869893 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020983 Uncertain Expressed in all skeletal muscle: 147.5 -ELMO2 CED-12, CED12, ELMO-2, FLJ11656, KIAA1834 ENSG00000062598 Engulfment and cell motility 2 20 46366049-46432985 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018811 Approved Supported Cytosol Expressed in all cerebral cortex: 58.4 -WAPL FOE, KIAA0261, WAPAL ENSG00000062650 WAPL cohesin release factor 10 86435256-86521815 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037874, HPA037875 Supported Expressed in all testis: 64.2 -VMP1 EPG3, TANGO5, TMEM49 ENSG00000062716 Vacuole membrane protein 1 17 59707192-59842255 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030773, HPA064780 Uncertain Approved Nucleoli
Endoplasmic reticulum Expressed in all spleen: 64.7 -APPBP2 Hs.84084, KIAA0228, PAT1 ENSG00000062725 Amyloid beta precursor protein (cytoplasmic tail) binding protein 2 17 60443149-60526219 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050874 Supported Cytosol Expressed in all testis: 44.5 -POLD1 CDC2, POLD ENSG00000062822 Polymerase (DNA directed), delta 1, catalytic subunit 19 50384204-50418018 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004375, HPA046524 Supported Supported Nucleoplasm Mixed bone marrow: 21.4 -SEZ6 ENSG00000063015 Seizure related 6 homolog (mouse) 17 28954901-29006440 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011777 Supported Uncertain Intermediate filaments Tissue enriched 51 cerebral cortex: 54.1 duodenum: 1.0 -EIF4B ENSG00000063046 Eukaryotic translation initiation factor 4B 12 53006158-53042209 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039072, HPA046164 Approved Validated Cytosol Expressed in all ovary: 756.6 -SLC6A16 NTT5 ENSG00000063127 Solute carrier family 6, member 16 19 49289638-49325225 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA076812 Approved Golgi apparatus Tissue enriched 18 testis: 161.8 lymph node: 9.0 -GLTSCR1 ENSG00000063169 Glioma tumor suppressor candidate region gene 1 19 47608196-47703277 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056211 Approved Approved Nucleoplasm Mixed parathyroid gland: 15.2 -SPHK2 ENSG00000063176 Sphingosine kinase 2 19 48619291-48630717 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065508 Supported Vesicles Mixed duodenum: 22.7 -RPL18 L18 ENSG00000063177 Ribosomal protein L18 19 48615328-48619536 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046572 Approved Validated Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 2568.3 -CA11 CARP2, CARPX1 ENSG00000063180 Carbonic anhydrase XI 19 48637942-48646312 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041778 Approved Vesicles
Microtubules Tissue enhanced 0 cerebral cortex: 244.8 ovary: 49.6 -ISOC2 FLJ23469 ENSG00000063241 Isochorismatase domain containing 2 19 55452985-55462343 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043142 Supported Approved Mitochondria
Cytosol Expressed in all kidney: 62.9 -U2AF2 U2AF65 ENSG00000063244 U2 small nuclear RNA auxiliary factor 2 19 55654146-55674715 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010910, HPA041943, HPA043562 Supported Validated Nucleoplasm
Nuclear speckles Expressed in all lymph node: 139.1 -EPN1 ENSG00000063245 Epsin 1 19 55675226-55709858 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009729, HPA061136 Approved Validated Cytosol Expressed in all duodenum: 91.9 -MED29 DKFZp434H247, IXL, MED2 ENSG00000063322 Mediator complex subunit 29 19 39391303-39400637 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055956 Supported Nucleoplasm Expressed in all parathyroid gland: 63.6 -AHRR AHH, AHHR, bHLHe77, KIAA1234 ENSG00000063438 Aryl-hydrocarbon receptor repressor 5 304176-438291 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021483 Supported Nucleoplasm
Cytosol Tissue enriched 8 testis: 65.3 skin: 7.9 -GSC2 GSCL ENSG00000063515 Goosecoid homeobox 2 22 19148576-19150283 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043011 Uncertain Tissue enriched 31 testis: 3.0 epididymis: 0.0 -ZNF275 ENSG00000063587 Zinc finger protein 275 X 153334155-153360110 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000566 Approved Approved Nucleoli Expressed in all adrenal gland: 79.7 -MTMR1 ENSG00000063601 Myotubularin related protein 1 X 150692971-150765103 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002977, HPA018502 Approved Approved Nucleoplasm
Vesicles
Plasma membrane Expressed in all parathyroid gland: 26.3 -GPC1 glypican ENSG00000063660 Glypican 1 2 240435671-240468078 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030571 Approved Supported Plasma membrane
Cytosol Tissue enhanced 0 skin: 266.0 prostate: 57.7 -ADCK1 FLJ39600 ENSG00000063761 AarF domain containing kinase 1 14 77800083-77935012 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051012, HPA055014 Uncertain Approved Nucleoplasm Mixed cerebral cortex: 9.0 -HAGH GLO2, GLXII, HAGH1 ENSG00000063854 Hydroxyacylglutathione hydrolase 16 1795620-1827194 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043041, HPA061143 Approved Expressed in all liver: 124.1 -RNF4 RES4-26, SLX5, SNURF ENSG00000063978 Ring finger protein 4 4 2462220-2625320 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049356 Approved Expressed in all testis: 56.5 -CASP8 Casp-8, FLICE, MACH, MCH5 ENSG00000064012 Caspase 8, apoptosis-related cysteine peptidase 2 201233443-201287711 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001302, CAB002047, HPA005688, HPA006191 Approved Validated Nucleoplasm
Cytosol Expressed in all spleen: 45.6 -LIMCH1 DKFZP686A01247, LIMCH1A, LMO7B ENSG00000064042 LIM and calponin homology domains 1 4 41359607-41700044 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004184, HPA063840 Uncertain Approved Actin filaments Mixed parathyroid gland: 187.4 -ASUN C12orf11, FLJ10637, Mat89Bb, NET48, SPATA30 ENSG00000064102 Asunder spermatogenesis regulator 12 26905181-26938326 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039543 Uncertain Expressed in all adrenal gland: 23.1 -TM7SF3 ENSG00000064115 Transmembrane 7 superfamily member 3 12 26973195-27014434 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041097, HPA057640 Uncertain Approved Nucleus
Cytosol Expressed in all kidney: 189.4 -DLX3 ENSG00000064195 Distal-less homeobox 3 17 49990005-49995224 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 5 placenta: 10.6;skin: 21.9 thyroid gland: 3.1 -SPA17 CT22, SP17 ENSG00000064199 Sperm autoantigenic protein 17 11 124673798-124697518 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037568 Supported Approved Vesicles Group enriched 7 fallopian tube: 122.8;testis: 427.5 epididymis: 37.3 -TSPAN32 PHEMX, TSSC6 ENSG00000064201 Tetraspanin 32 11 2301997-2318200 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA024135 Uncertain Tissue enhanced 0 bone marrow: 12.0 heart muscle: 6.8 -WISP2 CCN5, CT58, CTGF-L ENSG00000064205 WNT1 inducible signaling pathway protein 2 20 44714844-44728509 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB019273 Approved Tissue enhanced 0 cervix, uterine: 456.7;ovary: 167.0 breast: 69.2 -DMRT3 DMRTA3 ENSG00000064218 Doublesex and mab-3 related transcription factor 3 9 976964-991731 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 6 parathyroid gland: 64.1 thyroid gland: 10.3 -ST3GAL6 SIAT10, ST3GALVI ENSG00000064225 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 3 98732236-98821201 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018792 Approved Mixed liver: 28.4 -ATP2C2 KIAA0703, SPCA2 ENSG00000064270 ATPase, Ca++ transporting, type 2C, member 2 16 84368527-84464187 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052262, HPA075812 Approved Approved Plasma membrane
Focal adhesion sites Tissue enhanced 0 rectum: 39.0 skin: 30.1 -NGFR CD271, p75NTR, TNFRSF16 ENSG00000064300 Nerve growth factor receptor 17 49495293-49515017 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000143, CAB001995, HPA004765 Supported Approved Nucleoplasm
Plasma membrane Mixed adipose tissue: 32.2 -CDON CDO, CDON1, ORCAM ENSG00000064309 Cell adhesion associated, oncogene regulated 11 125955796-126063335 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012422, HPA017377 Uncertain Tissue enhanced 0 thyroid gland: 75.1 ovary: 53.3 -TAF2 CIF150, TAF2B, TAFII150 ENSG00000064313 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 8 119730775-119832863 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 25.4 -HIPK2 ENSG00000064393 Homeodomain interacting protein kinase 2 7 139561570-139777778 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA007611 Supported Supported Nucleus Expressed in all cerebral cortex: 61.5 -TNPO3 IPO12, LGMD1F, MTR10A, TRN-SR, TRN-SR2 ENSG00000064419 Transportin 3 7 128954180-129055173 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039555, HPA041537 Approved Validated Vesicles Expressed in all testis: 48.3 -BORCS8-MEF2B MEF2BNB-MEF2B ENSG00000064489 BORCS8-MEF2B readthrough 19 19145567-19192158 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA004734 Uncertain Mixed fallopian tube: 1.4 -RFXANK ANKRA1, BLS, F14150_1, MGC138628, RFX-B ENSG00000064490 Regulatory factor X-associated ankyrin-containing protein 19 19192229-19201869 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049157, HPA053330 Approved Validated Nucleoplasm Expressed in all fallopian tube: 49.7 -TMEM161A FLJ20422, FLJ39645 ENSG00000064545 Transmembrane protein 161A 19 19119169-19138513 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043365 Approved Approved Cytosol Expressed in all parathyroid gland: 20.9 -LPAR2 EDG-4, EDG4, LPA2 ENSG00000064547 Lysophosphatidic acid receptor 2 19 19623668-19628930 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019616 Approved Mixed testis: 40.7 -CTSA GSL, PPGB ENSG00000064601 Cathepsin A 20 45890144-45898820 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB024930, HPA031068 Supported Validated Vesicles Expressed in all adrenal gland: 244.6 -SUGP2 KIAA0365, SFRS14 ENSG00000064607 SURP and G patch domain containing 2 19 18990888-19034023 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041557, HPA061111 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all testis: 161.3 -SLC12A2 BSC, BSC2, NKCC1, PPP1R141 ENSG00000064651 Solute carrier family 12 (sodium/potassium/chloride transporter), member 2 5 128083766-128189688 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020130, HPA063697 Approved Approved Vesicles
Plasma membrane Expressed in all rectum: 66.4 -SNX24 SBBI31 ENSG00000064652 Sorting nexin 24 5 122843439-123029354 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044566, HPA073934 Approved Approved Vesicles Expressed in all esophagus: 39.5 -EYA2 EAB1 ENSG00000064655 EYA transcriptional coactivator and phosphatase 2 20 46894624-47188844 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA027024, HPA059291 Uncertain Supported Cytosol Tissue enhanced 0 cervix, uterine: 75.8 fallopian tube: 49.5 -CNN2 ENSG00000064666 Calponin 2 19 1026581-1039068 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049095 Approved Approved Nucleoplasm
Actin filaments
Cytosol Expressed in all lymph node: 211.5 -ABCA7 ABCX ENSG00000064687 ATP-binding cassette, sub-family A (ABC1), member 7 19 1040101-1065572 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041564 Supported Supported Golgi apparatus
Plasma membrane
Cell Junctions Mixed spleen: 25.8 -SNCAIP SYPH1 ENSG00000064692 Synuclein, alpha interacting protein 5 122311354-122464219 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA064687 Uncertain Supported Cytoplasmic bodies Tissue enhanced 0 endometrium: 30.0;ovary: 43.3 cervix: 26.0 -DDX20 DP103, GEMIN3 ENSG00000064703 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 1 111755245-111768016 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005516, CAB015427, HPA023541 Approved Supported Nucleus
Nuclear bodies
Cytosol Tissue enriched 10 testis: 130.0 parathyroid gland: 12.4 -BTBD1 ENSG00000064726 BTB (POZ) domain containing 1 15 83016422-83067354 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067671 Supported Expressed in all skeletal muscle: 109.7 -FAR2 FLJ10462, MLSTD1, SDR10E2 ENSG00000064763 Fatty acyl CoA reductase 2 12 29149103-29340980 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015884 Approved Approved Nucleoli
Golgi apparatus Mixed epididymis: 52.9 -BCAS1 AIBC1, NABC1 ENSG00000064787 Breast carcinoma amplified sequence 1 20 53936777-54070594 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033558, HPA051816, HPA054745 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 109.0;stomach: 156.7 rectum: 82.3 -POU1F1 GHF-1, PIT1, POU1F1a ENSG00000064835 POU class 1 homeobox 1 3 87259404-87276587 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA041646, HPA050624 Supported Not detected epididymis: 0.1 -CHI3L2 YKL-39, YKL39 ENSG00000064886 Chitinase 3-like 2 1 111200771-111243440 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005443 Uncertain Tissue enhanced 0 appendix: 156.7 tonsil: 107.4 -SBNO2 FLJ00173, KIAA0963, Sno, Stno ENSG00000064932 Strawberry notch homolog 2 (Drosophila) 19 1107636-1174283 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041867 Approved Mixed adipose tissue: 14.1 -PMS1 MLH2, PMSL1 ENSG00000064933 PMS1 homolog 1, mismatch repair system component 2 189784085-189877629 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010233, HPA031013 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 84.8 -HMG20B BRAF25, BRAF35, HMGX2, HMGXB2, SMARCE1r, SOXL ENSG00000064961 High mobility group 20B 19 3572777-3579088 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050220, HPA053157, HPA069832 Approved Validated Nucleoplasm Expressed in all prostate: 64.9 -CALCRL CGRPR, CRLR ENSG00000064989 Calcitonin receptor-like 2 187343129-187448460 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008070, HPA046515 Uncertain Supported Plasma membrane Tissue enhanced 0 lung: 114.4 adipose tissue: 76.3 -TAF11 TAF2I, TAFII28 ENSG00000064995 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 6 34877778-34888089 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029326, HPA049127 Supported Nucleoplasm
Golgi apparatus Expressed in all testis: 54.9 -ANKS1A ANKS1, KIAA0229 ENSG00000064999 Ankyrin repeat and sterile alpha motif domain containing 1A 6 34889265-35091413 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036768, HPA036769 Approved Approved Nucleoplasm
Cytosol Expressed in all placenta: 38.9 -AP3D1 ADTD ENSG00000065000 Adaptor-related protein complex 3, delta 1 subunit 19 2100988-2164465 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA074408 Approved Cytosol Expressed in all testis: 60.8 -ZNF76 D6S229E, Zfp523, ZNF523 ENSG00000065029 Zinc finger protein 76 6 35258909-35295985 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030090, HPA030091 Approved Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 34.5 -SLC9A3R2 E3KARP, NHERF-2, SIP-1, TKA-1 ENSG00000065054 Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 16 2025356-2039026 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001672 Approved Supported Plasma membrane Mixed lung: 161.9 -NTHL1 NTH1, OCTS3 ENSG00000065057 Nth-like DNA glycosylase 1 16 2039815-2047866 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025152 Supported Expressed in all fallopian tube: 21.1 -UHRF1BP1 C6orf107, dJ349A12.1, FLJ20302, ICBP90 ENSG00000065060 UHRF1 binding protein 1 6 34792015-34883138 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032099, HPA032100 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all testis: 22.4 -GNAI3 87U6 ENSG00000065135 Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1 109548611-109618321 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022099, HPA042141 Approved Supported Nucleus
Nucleoli
Centrosome Mixed esophagus: 8.0 -IPO5 IMB3, KPNB3, MGC2068, Pse1, RANBP5 ENSG00000065150 Importin 5 13 97953658-98024297 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009110, HPA040983, HPA056548 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 382.6 -OAT HOGA ENSG00000065154 Ornithine aminotransferase 10 124397303-124418976 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033576, HPA040098, HPA064742 Supported Supported Nucleoplasm
Mitochondria Expressed in all small intestine: 877.2 -WDR3 DIP2, FLJ12796, UTP12 ENSG00000065183 WD repeat domain 3 1 117929720-117966542 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027509, HPA054354 Approved Supported Nucleus
Nuclear membrane
Nucleoli Expressed in all testis: 22.3 -PKN2 Pak-2, PRK2, PRKCL2, STK7 ENSG00000065243 Protein kinase N2 1 88684222-88836255 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034861 Uncertain Expressed in all parathyroid gland: 48.2 -WDR18 Ipi3 ENSG00000065268 WD repeat domain 18 19 984271-998438 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050193, HPA050200 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 18.0 -TRAM2 KIAA0057 ENSG00000065308 Translocation associated membrane protein 2 6 52497402-52576915 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035092, HPA057925 Approved Approved Cytosol Expressed in all placenta: 51.8 -NTN1 NTN1L ENSG00000065320 Netrin 1 17 9021542-9244000 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056419 Approved Mixed heart muscle: 23.7 -GLP2R ENSG00000065325 Glucagon-like peptide 2 receptor 17 9822206-9892102 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB022690, HPA049244 Supported Supported Plasma membrane Tissue enhanced 0 gallbladder: 19.4 duodenum: 10.4 -MCM10 CNA43, DNA43, PRO2249 ENSG00000065328 Minichromosome maintenance 10 replication initiation factor 10 13161554-13211104 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045899, HPA071952 Approved Supported Nucleus
Nucleoli Mixed bone marrow: 5.9 -DGKA DAGK, DAGK1, DGK-alpha ENSG00000065357 Diacylglycerol kinase, alpha 80kDa 12 55927319-55954027 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041645, HPA045462 Approved Approved Nucleoplasm
Vesicles
Mitochondria Mixed skin: 97.3 -ERBB3 HER3, LCCS2 ENSG00000065361 Erb-b2 receptor tyrosine kinase 3 12 56079857-56103505 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025331, HPA045396 Uncertain Approved Plasma membrane
Actin filaments Mixed small intestine: 88.5 -ROPN1 CT91, ODF6, ROPN1A, ropporin ENSG00000065371 Rhophilin associated tail protein 1 3 123968521-123992178 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB014875, HPA052530 Approved Tissue enriched 9 testis: 222.9 breast: 24.1 -ANKRD44 PP6-ARS-B ENSG00000065413 Ankyrin repeat domain 44 2 196967017-197311173 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030122, HPA056549 Approved Approved Nuclear speckles
Mitochondria Mixed lymph node: 40.8 -KARS DFNB89, KARS1, KARS2 ENSG00000065427 Lysyl-tRNA synthetase 16 75627474-75648643 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041345, HPA041550 Supported Supported Cytosol Expressed in all testis: 177.7 -ADAT1 ENSG00000065457 Adenosine deaminase, tRNA-specific 1 16 75596981-75623300 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040713, HPA040903 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 89.6 -PDIA5 FLJ30401, PDIR ENSG00000065485 Protein disulfide isomerase family A, member 5 3 123067062-123225227 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030353, HPA030355 Approved Approved Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus Mixed placenta: 70.2 -TBC1D22B C6orf197, dJ744I24.2, FLJ20337 ENSG00000065491 TBC1 domain family, member 22B 6 37257772-37332970 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027908, HPA027909, HPA027910 Uncertain Uncertain Nucleoplasm
Cytosol Expressed in all testis: 18.7 -NDUFB4 B15 ENSG00000065518 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 3 120596309-120602500 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051739 Supported Supported Nuclear membrane
Mitochondria Expressed in all adrenal gland: 365.9 -SPEN KIAA0929, MINT, RBM15C, SHARP ENSG00000065526 Spen family transcriptional repressor 1 15847864-15940460 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015825, HPA050257 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 38.3 -MYLK MLCK, MLCK1, MYLK1, smMLCK ENSG00000065534 Myosin light chain kinase 3 123610049-123884331 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020789, HPA031677 Supported Supported Cytosol Expressed in all smooth muscle: 2971.5 -ZC3H15 LEREPO4 ENSG00000065548 Zinc finger CCCH-type containing 15 2 186486156-186509363 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031099, HPA031100, HPA031101 Supported Validated Cytosol Expressed in all thyroid gland: 78.2 -MAP2K4 JNKK1, MEK4, MKK4, PRKMK4, SERK1 ENSG00000065559 Mitogen-activated protein kinase kinase 4 17 12020824-12143830 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007751, HPA060074 Supported Approved Nucleoplasm
Cell Junctions Expressed in all cerebral cortex: 64.2 -TMEM206 C1orf75, FLJ10874 ENSG00000065600 Transmembrane protein 206 1 212363931-212414901 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008540 Uncertain Tissue enhanced 0 cerebral cortex: 25.4 kidney: 10.6 -SNAP91 AP180, CALM, KIAA0656 ENSG00000065609 Synaptosomal-associated protein, 91kDa 6 83552880-83709691 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009745, HPA029632, HPA029633 Supported Uncertain Centrosome
Cytosol Tissue enriched 7 cerebral cortex: 152.6 testis: 22.4 -SLK KIAA0204, se20-9, STK2 ENSG00000065613 STE20-like kinase 10 103967201-104029233 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015757 Approved Approved Plasma membrane
Cytosol Expressed in all esophagus: 61.2 -CYB5R4 b5+b5R, dJ676J13.1, NCB5OR ENSG00000065615 Cytochrome b5 reductase 4 6 83859643-83967424 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018992 Approved Expressed in all testis: 22.5 -COL17A1 BP180, BPAG2 ENSG00000065618 Collagen, type XVII, alpha 1 10 104031286-104086002 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043673, HPA052963 Supported Tissue enriched 15 skin: 770.5 placenta: 52.8 -GSTO2 ENSG00000065621 Glutathione S-transferase omega 2 10 104268873-104304945 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048141 Approved Approved Nucleus
Nucleoli Mixed testis: 36.0 -SEC61A2 FLJ10578 ENSG00000065665 Sec61 translocon alpha 2 subunit 10 12129637-12169961 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 51.4 testis: 32.3 -PRKCQ ENSG00000065675 Protein kinase C, theta 10 6427143-6580301 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065279, HPA073098 Supported Microtubule organizing center Tissue enhanced 0 skeletal muscle: 43.0 thyroid gland: 24.8 -TLE2 ESG, ESG2, FLJ41188, GRG2 ENSG00000065717 Transducin-like enhancer of split 2 19 2997638-3047635 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049103 Approved Supported Nuclear bodies
Focal adhesion sites Mixed seminal vesicle: 39.1 -ASB1 ASB-1 ENSG00000065802 Ankyrin repeat and SOCS box containing 1 2 238426742-238452250 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003508 Uncertain Approved Nucleoplasm Mixed cerebral cortex: 20.1 -FAM107B C10orf45, FLJ45505, MGC11034 ENSG00000065809 Family with sequence similarity 107, member B 10 14518557-14774897 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039661, HPA058814 Uncertain Supported Nucleoplasm Expressed in all lymph node: 182.3 -ME1 ENSG00000065833 Malic enzyme 1, NADP(+)-dependent, cytosolic 6 83210389-83431071 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006493 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Mixed parathyroid gland: 53.1 -TBC1D1 KIAA1108, TBC, TBC1 ENSG00000065882 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 4 37891087-38139175 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041816, HPA058158 Approved Uncertain Nucleoli Expressed in all parathyroid gland: 247.3 -CDK13 CDC2L, CDC2L5, CHED, KIAA1791 ENSG00000065883 Cyclin-dependent kinase 13 7 39950037-40097134 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059241 Uncertain Supported Nuclear speckles Expressed in all parathyroid gland: 32.9 -MTHFD2 ENSG00000065911 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 74198562-74217565 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB003684, HPA049657 Approved Expressed in all appendix: 40.7 -SLC9A7 NHE7 ENSG00000065923 Solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 X 46599252-46759172 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048938, HPA075385 Approved Supported Vesicles Mixed cerebral cortex: 14.4 -FOXJ2 FHX ENSG00000065970 Forkhead box J2 12 8032703-8055503 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008723 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all parathyroid gland: 28.5 -YBX1 BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1 ENSG00000065978 Y box binding protein 1 1 42682427-42702349 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005875, HPA040304, HPA057159 Supported Validated Vesicles
Cytosol Expressed in all testis: 1538.1 -PDE4A DPDE2 ENSG00000065989 Phosphodiesterase 4A, cAMP-specific 19 10416773-10469631 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017632, HPA043310, HPA076091 Uncertain Supported Plasma membrane Mixed parathyroid gland: 33.4 -PPP2R5A B56A, PR61A ENSG00000066027 Protein phosphatase 2, regulatory subunit B', alpha 1 212285537-212361863 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059288 Supported Cytosol Expressed in all lung: 86.6 -CTNNA2 CAP-R, CT114 ENSG00000066032 Catenin (cadherin-associated protein), alpha 2 2 79185231-80648861 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB037175 Approved Group enriched 12 cerebral cortex: 111.9;epididymis: 80.2;testis: 32.0 adrenal gland: 6.4 -ELAVL1 Hua, HUR, MelG ENSG00000066044 ELAV like RNA binding protein 1 19 7958579-8445041 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005256, HPA046298 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all testis: 82.2 -TIE1 JTK14, TIE ENSG00000066056 Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1 43300993-43323108 Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045769 Approved Vesicles Tissue enhanced 0 placenta: 70.1 lung: 40.1 -DIP2B FLJ34278, KIAA1463 ENSG00000066084 Disco-interacting protein 2 homolog B 12 50504985-50748667 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038472, HPA046133, HPA056045 Approved Approved Endoplasmic reticulum Expressed in all cerebral cortex: 31.1 -SMARCD1 BAF60A, CRACD1, Rsc6p ENSG00000066117 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 12 50084972-50100712 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004101 Supported Approved Nucleoplasm
Vesicles Expressed in all parathyroid gland: 84.7 -KDM4A JHDM3A, JMJD2, JMJD2A, KIAA0677, TDRD14A ENSG00000066135 Lysine (K)-specific demethylase 4A 1 43650158-43705515 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007610 Uncertain Supported Nucleoli fibrillar center Expressed in all parathyroid gland: 30.6 -NFYC CBF-C, NF-YC ENSG00000066136 Nuclear transcription factor Y, gamma 1 40691570-40771603 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055011 Supported Nucleoplasm Expressed in all thyroid gland: 60.0 -ZMYND12 DKFZp434N2435 ENSG00000066185 Zinc finger, MYND-type containing 12 1 42430329-42456267 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 23.1;testis: 51.6 epididymis: 8.6 -SLC9A3 NHE3 ENSG00000066230 Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 5 473310-524332 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036493, HPA036669 Supported Supported Plasma membrane Tissue enhanced 0 colon: 82.6;small intestine: 74.1 gallbladder: 66.3 -NGEF ARHGEF27 ENSG00000066248 Neuronal guanine nucleotide exchange factor 2 232878686-233013272 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008160 Approved Uncertain Plasma membrane
Cytosol Tissue enhanced 0 adrenal gland: 66.8;cerebral cortex: 151.9 duodenum: 44.0 -ASPM ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5 ENSG00000066279 Abnormal spindle microtubule assembly 1 197084128-197146694 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017816 Approved Approved Plasma membrane
Cytosol Tissue enhanced 0 bone marrow: 11.0 lymph node: 9.6 -CD84 hCD84, mCD84, SLAMF5 ENSG00000066294 CD84 molecule 1 160541095-160579516 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070502 Supported Tissue enhanced 0 lymph node: 28.8 appendix: 27.5 -ELOVL1 Ssc1 ENSG00000066322 ELOVL fatty acid elongase 1 1 43363397-43368074 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033426, HPA056557 Approved Approved Endoplasmic reticulum Expressed in all skin: 157.0 -SPI1 OF, PU.1, SFPI1, SPI-1, SPI-A ENSG00000066336 Spi-1 proto-oncogene 11 47354860-47378576 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004079, HPA044653 Supported Supported Nucleoplasm Expressed in all bone marrow: 212.9 -ZNRD1 HTEX-6, hZR14, RPA12, tctex-6 ENSG00000066379 Zinc ribbon domain containing 1 6 30058899-30064909 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055074 Supported Nucleoli fibrillar center Mixed lymph node: 6.0 -MPPED2 239FB, C11orf8, D11S302E, dJ1024C24.1, dJ873F21.1, FAM1B, Hs.46638 ENSG00000066382 Metallophosphoesterase domain containing 2 11 30384493-30586872 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062575 Approved Nucleoli
Vesicles
Mitochondria Tissue enhanced 0 cervix, uterine: 38.4;thyroid gland: 43.4 prostate: 21.5 -CLDN18 SFTPJ ENSG00000066405 Claudin 18 3 137998735-138033655 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB013010, CAB013243, HPA018446 Supported Group enriched 99 lung: 362.1;stomach: 695.3 gallbladder: 5.3 -ZBTB11 ZNF-U69274, ZNF913 ENSG00000066422 Zinc finger and BTB domain containing 11 3 101648889-101677495 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015328, HPA024138 Approved Validated Nucleoplasm Expressed in all bone marrow: 23.5 -ATXN3 ATX3, JOS, MJD, SCA3 ENSG00000066427 Ataxin 3 14 92038652-92106621 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021976, HPA024123, HPA069338 Uncertain Supported Nucleus
Nucleoli
Plasma membrane Mixed testis: 18.5 -GOLGA5 golgin-84, GOLIM5, ret-II, rfg5 ENSG00000066455 Golgin A5 14 92794231-92839963 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000992, HPA063876 Supported Supported Supported Golgi apparatus Expressed in all epididymis: 64.2 -FGFR2 BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25 ENSG00000066468 Fibroblast growth factor receptor 2 10 121478334-121598458 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010886, HPA035305, HPA056562 Uncertain Approved Vesicles Mixed skin: 97.5 -LRRC40 FLJ20331 ENSG00000066557 Leucine rich repeat containing 40 1 70144805-70205620 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026564 Approved Approved Nucleoli Expressed in all testis: 21.6 -ISOC1 CGI-111 ENSG00000066583 Isochorismatase domain containing 1 5 129094751-129114028 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA070307 Approved Endoplasmic reticulum
Vesicles Expressed in all endometrium: 174.3 -EML1 ELP79, EMAP, EMAPL, HuEMAP ENSG00000066629 Echinoderm microtubule associated protein like 1 14 99737693-99942060 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033137, HPA049105 Uncertain Mixed parathyroid gland: 51.4 -TRMT11 C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1 ENSG00000066651 TRNA methyltransferase 11 homolog 6 125986430-126039276 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030473 Approved Nuclear bodies Expressed in all endometrium: 23.3 -THUMPD1 FLJ20274, Tan1 ENSG00000066654 THUMP domain containing 1 16 20733664-20742084 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027851 Approved Approved Cytosol Expressed in all parathyroid gland: 67.5 -MSANTD3 C9orf30, MGC17337 ENSG00000066697 Myb/SANT-like DNA-binding domain containing 3 9 100427156-100451711 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062662 Approved Nucleoplasm Expressed in all gallbladder: 23.5 -KIF26A DKFZP434N178, KIAA1236 ENSG00000066735 Kinesin family member 26A 14 104138723-104180894 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046882, HPA060346 Uncertain Approved Nucleus
Plasma membrane
Cytosol Mixed adipose tissue: 5.0 -ATG2B C14orf103, FLJ10242 ENSG00000066739 Autophagy related 2B 14 96279202-96363870 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000880, HPA001427, HPA019665 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 16.8 -ARFGEF1 ARFGEP1, BIG1, DKFZP434L057, p200 ENSG00000066777 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 8 67173511-67343677 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023399, HPA023822 Supported Approved Validated Nucleoplasm
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 58.6 -ACSM2B ACSM2, HXMA, HYST1046 ENSG00000066813 Acyl-CoA synthetase medium-chain family member 2B 16 20536226-20576427 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057699 Supported Group enriched 85 kidney: 423.8;liver: 261.6 thyroid gland: 4.0 -ZFAT KIAA1485, ZFAT1, ZNF406 ENSG00000066827 Zinc finger and AT hook domain containing 8 134477788-134713049 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020989, HPA063592 Supported Approved Nucleoplasm
Nuclear bodies Group enriched 6 kidney: 10.4;placenta: 44.0 testis: 4.4 -MTFR1 CHPPR, FAM54A2, KIAA0009 ENSG00000066855 Mitochondrial fission regulator 1 8 65644734-65771261 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023152, HPA056120 Uncertain Supported Mitochondria
Cytosol Expressed in all testis: 34.9 -STAG3 ENSG00000066923 Stromal antigen 3 7 100177563-100221488 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047030, HPA049106, HPA058330 Supported Group enriched 6 fallopian tube: 29.6;testis: 129.0 cerebral cortex: 12.3 -FECH ENSG00000066926 Ferrochelatase 18 57548283-57586772 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044100, HPA048177 Approved Expressed in all bone marrow: 93.5 -MYO9A FLJ11061, FLJ13244, MGC71859 ENSG00000066933 Myosin IXA 15 71822289-72118577 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039812, HPA040071 Approved Approved Plasma membrane Tissue enhanced 0 testis: 51.3 thyroid gland: 22.1 -DDX3Y DBY ENSG00000067048 DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked Y 12904108-12920478 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001648, HPA005631 Uncertain Approved Supported Nucleus
Cytosol Tissue enhanced 0 testis: 128.2 bone marrow: 53.9 -PFKP PFK-C, PFKF ENSG00000067057 Phosphofructokinase, platelet 10 3066333-3137712 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018257, HPA056484 Uncertain Supported Cytosol Expressed in all testis: 286.0 -IDI1 ENSG00000067064 Isopentenyl-diphosphate delta isomerase 1 10 1039908-1049170 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039169 Approved Expressed in all breast: 241.1 -SP100 ENSG00000067066 SP100 nuclear antigen 2 230415942-230544090 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016707, HPA017384 Supported Supported Nucleus
Nuclear bodies Expressed in all bone marrow: 139.9 -KLF6 BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9 ENSG00000067082 Kruppel-like factor 6 10 3775996-3785281 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB013529, HPA069585 Supported Approved Nucleus
Nucleoli fibrillar center
Vesicles
Cytosol Expressed in all thyroid gland: 321.3 -PLPP1 LPP1, PAP-2a, PPAP2A ENSG00000067113 Phospholipid phosphatase 1 5 55424854-55535050 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033331, HPA047815 Supported Supported Plasma membrane Mixed prostate: 344.0 -NEO1 HsT17534, IGDCC2, NGN, NTN1R2 ENSG00000067141 Neogenin 1 15 73051710-73305206 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009320, HPA027804, HPA027805, HPA027806 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Mixed parathyroid gland: 100.9 -TRAM1 TRAM, TRAMP ENSG00000067167 Translocation associated membrane protein 1 8 70573442-70608387 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023929 Approved Expressed in all thyroid gland: 316.6 -PHKA1 PHKA ENSG00000067177 Phosphorylase kinase, alpha 1 (muscle) X 72578814-72714319 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001081 Supported Approved Vesicles Tissue enhanced 0 parathyroid gland: 39.3;skeletal muscle: 35.6 adrenal gland: 15.6 -TNFRSF1A CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60 ENSG00000067182 Tumor necrosis factor receptor superfamily, member 1A 12 6328757-6342114 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004102, CAB010309 Approved Expressed in all gallbladder: 140.8 -CACNB1 CACNLB1 ENSG00000067191 Calcium channel, voltage-dependent, beta 1 subunit 17 39173456-39197703 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023343 Approved Group enriched 6 cerebral cortex: 46.9;skeletal muscle: 108.5 skin: 12.3 -EVI5 NB4S ENSG00000067208 Ecotropic viral integration site 5 1 92508696-92792404 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027339, HPA053724 Approved Supported Golgi apparatus
Vesicles Mixed parathyroid gland: 15.2 -STOML1 FLJ36370, hUNC-24, SLP-1, STORP ENSG00000067221 Stomatin (EPB72)-like 1 15 73978923-73994622 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042353 Approved Approved Cytosol Expressed in all cerebral cortex: 43.8 -PKM OIP3, PK3, PKM2, THBP1 ENSG00000067225 Pyruvate kinase, muscle 15 72199029-72231822 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019421, HPA029501 Uncertain Validated Cytosol Expressed in all skeletal muscle: 1492.7 -DHX29 DDX29 ENSG00000067248 DEAH (Asp-Glu-Ala-His) box polypeptide 29 5 55256245-55307722 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038317, HPA038318 Uncertain Approved Cytosol Expressed in all parathyroid gland: 38.0 -DNTTIP2 ERBP, HSU15552, TdIF2 ENSG00000067334 Deoxynucleotidyltransferase, terminal, interacting protein 2 1 93866283-93879918 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044502, HPA053707 Supported Validated Nucleoli Mixed bone marrow: 10.8 -METTL22 C16orf68, FLJ12433, MGC2654 ENSG00000067365 Methyltransferase like 22 16 8621683-8649654 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040803, HPA059882, HPA074173 Uncertain Supported Nucleus
Nucleoli Mixed testis: 15.9 -TP53BP1 53BP1, p202, TDRD30 ENSG00000067369 Tumor protein p53 binding protein 1 15 43403061-43510728 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004083, HPA008788, HPA022133 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 49.6 -TRO KIAA1114, MAGE-D3, MAGED3 ENSG00000067445 Trophinin X 54920462-54931431 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033947, HPA053358 Uncertain Approved Nucleus
Nucleoli fibrillar center Mixed cerebral cortex: 30.0 -RRP15 CGI-115, KIAA0507 ENSG00000067533 Ribosomal RNA processing 15 homolog 1 218285287-218337983 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024639 Approved Approved Nucleus
Nucleoli
Mitochondria Mixed parathyroid gland: 7.7 -RHOA ARH12, ARHA, Rho12, RhoA, RHOH12 ENSG00000067560 Ras homolog family member A 3 49359145-49412998 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005052 Approved Supported Cytosol Expressed in all lung: 592.9 -DHX8 DDX8, HRH1, PRP22, PRPF22 ENSG00000067596 DEAH (Asp-Glu-Ala-His) box polypeptide 8 17 43483865-43544463 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049285 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 54.2 -PRKCZ PKC2 ENSG00000067606 Protein kinase C, zeta 1 2050470-2185395 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021851 Supported Approved Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 100.0 placenta: 59.9 -ZFY ZNF911 ENSG00000067646 Zinc finger protein, Y-linked Y 2935281-2982506 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001748, HPA071863 Uncertain Approved Nucleoplasm
Nucleoli Mixed testis: 12.8 -IARS2 FLJ10326 ENSG00000067704 Isoleucyl-tRNA synthetase 2, mitochondrial 1 220094102-220148041 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024212, HPA024594, HPA024596 Supported Validated Mitochondria Expressed in all parathyroid gland: 141.6 -SYT1 P65, SVP65, SYT ENSG00000067715 Synaptotagmin I 12 78863993-79452008 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008394, HPA064788 Supported Tissue enriched 13 cerebral cortex: 477.9 smooth muscle: 36.4 -NAV3 KIAA0938, POMFIL1 ENSG00000067798 Neuron navigator 3 12 77830905-78213008 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032111, HPA032112, CAB037063 Uncertain Approved Nuclear membrane
Cytosol Tissue enhanced 0 cerebral cortex: 23.1;ovary: 22.9 spleen: 12.1 -IDH3G ENSG00000067829 Isocitrate dehydrogenase 3 (NAD+) gamma X 153785766-153794523 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000425, HPA002017 Supported Validated Mitochondria Expressed in all cerebral cortex: 65.1 -ROGDI FLJ22386 ENSG00000067836 Rogdi homolog 16 4796968-4802950 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041000 Uncertain Expressed in all cerebral cortex: 39.3 -PDZD4 FLJ34125, KIAA1444, LU1, PDZK4, PDZRN4L ENSG00000067840 PDZ domain containing 4 X 153802166-153830565 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003878 Approved Tissue enriched 9 cerebral cortex: 123.9 seminal vesicle: 13.6 -ATP2B3 CFAP39, CLA2, PMCA3, SCAX1 ENSG00000067842 ATPase, Ca++ transporting, plasma membrane 3 X 153517676-153582939 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001583 Supported Uncertain Golgi apparatus
Plasma membrane Group enriched 8 adrenal gland: 12.2;cerebral cortex: 19.1 fallopian tube: 2.0 -ROCK1 p160ROCK ENSG00000067900 Rho-associated, coiled-coil containing protein kinase 1 18 20946906-21111851 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004562, HPA007567, HPA045639 Approved Mixed bone marrow: 12.4 -CBFB PEBP2B ENSG00000067955 Core-binding factor, beta subunit 16 67029116-67101058 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038852 Uncertain Approved Nucleus
Cytosol Expressed in all parathyroid gland: 95.6 -PDK3 ENSG00000067992 Pyruvate dehydrogenase kinase, isozyme 3 X 24465221-24539837 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046583, HPA072492 Approved Supported Nucleoli
Mitochondria Mixed testis: 24.8 -HYAL2 LuCa-2, LUCA2 ENSG00000068001 Hyaluronoglucosaminidase 2 3 50317790-50322906 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036436, HPA077941 Uncertain Approved Endoplasmic reticulum Expressed in all spleen: 217.8 -HDAC4 BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288 ENSG00000068024 Histone deacetylase 4 2 239048168-239401654 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004431, HPA048723 Approved Supported Nucleoplasm
Cytosol Mixed cerebral cortex: 19.4 -RASSF1 123F2, NORE2A, RDA32, REH3P21 ENSG00000068028 Ras association (RalGDS/AF-6) domain family member 1 3 50329782-50340980 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040735 Approved Expressed in all bone marrow: 51.9 -FGFR3 ACH, CD333, CEK2, JTK4 ENSG00000068078 Fibroblast growth factor receptor 3 4 1793307-1808872 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004231, HPA067204 Supported Supported Endoplasmic reticulum Tissue enriched 7 skin: 334.6 cerebral cortex: 49.7 -IFI35 IFP35 ENSG00000068079 Interferon-induced protein 35 17 43006725-43014456 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045946 Approved Nucleoplasm
Cytosol Expressed in all spleen: 44.8 -HEATR6 ABC1, FLJ22087 ENSG00000068097 HEAT repeat containing 6 17 60043194-60078931 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030789, HPA062157 Uncertain Approved Mitochondria Mixed parathyroid gland: 13.0 -COASY CoASY, DPCK, NBP, PPAT ENSG00000068120 CoA synthase 17 42561467-42566277 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022875, HPA022912, HPA023273 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 58.9 -PLEKHH3 FLJ21019 ENSG00000068137 Pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 17 42667914-42676994 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046234 Uncertain Approved Golgi apparatus Expressed in all skin: 11.6 -MEF2A RSRFC4, RSRFC9 ENSG00000068305 Myocyte enhancer factor 2A 15 99565417-99716466 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004499, HPA046597 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 68.4 -OTUD5 DKFZp761A052, DUBA ENSG00000068308 OTU deubiquitinase 5 X 48922028-48958386 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017375 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all cerebral cortex: 70.1 -TFE3 bHLHe33, TFEA ENSG00000068323 Transcription factor binding to IGHM enhancer 3 X 49028726-49043486 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023881 Approved Supported Nucleoplasm
Cytosol Expressed in all seminal vesicle: 24.2 -TBC1D25 OATL1 ENSG00000068354 TBC1 domain family, member 25 X 48539457-48562609 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029197 Approved Expressed in all parathyroid gland: 12.7 -ACSL4 ACS4, FACL4, LACS4, MRX63, MRX68 ENSG00000068366 Acyl-CoA synthetase long-chain family member 4 X 109624244-109733403 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000286, HPA005552 Supported Approved Golgi apparatus
Mitochondria Expressed in all cervix: 70.3 -INPP5A 5PTASE ENSG00000068383 Inositol polyphosphate-5-phosphatase A 10 132537820-132783480 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012285, HPA066549 Supported Approved Cytosol Expressed in all smooth muscle: 60.5 -GPKOW GPATC5, GPATCH5, Spp2, T54 ENSG00000068394 G patch domain and KOW motifs X 49113389-49123801 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000287, HPA001894 Supported Validated Nucleoplasm Expressed in all cerebral cortex: 30.9 -GRIPAP1 DKFZp434P0630, GRASP-1, GRASP1, KIAA1167, MPMGp800B12492Q3 ENSG00000068400 GRIP1 associated protein 1 X 48973720-49002264 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000282, HPA000615 Approved Approved Vesicles
Cytosol Expressed in all cerebral cortex: 68.7 -FTSJ1 CDLIV, JM23, MRX44, MRX9, SPB1, TRM7, TRMT7 ENSG00000068438 FtsJ RNA methyltransferase homolog 1 (E. coli) X 48476021-48486364 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002718 Approved Approved Cytosol Expressed in all cervix: 24.5 -PRR11 FLJ11029 ENSG00000068489 Proline rich 11 17 59155499-59204705 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023923, HPA052376 Uncertain Approved Endoplasmic reticulum Mixed lymph node: 11.3 -REEP1 C2orf23, FLJ13110, SPG31 ENSG00000068615 Receptor accessory protein 1 2 86213993-86338083 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058061 Approved Tissue enhanced 0 cerebral cortex: 54.2;testis: 90.8 smooth muscle: 34.1 -ATP11A ATPIH, ATPIS, KIAA1021 ENSG00000068650 ATPase, class VI, type 11A 13 112690329-112887168 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035583, HPA035584 Approved Validated Vesicles Expressed in all lung: 59.2 -POLR1A DKFZP586M0122, FLJ21915, RPA1, RPO1-4 ENSG00000068654 Polymerase (RNA) I polypeptide A, 194kDa 2 86020216-86106155 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010145, HPA031513, HPA049700 Supported Supported Nucleus
Nucleoli fibrillar center Expressed in all parathyroid gland: 12.1 -LAPTM4A HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp ENSG00000068697 Lysosomal protein transmembrane 4 alpha 2 20032650-20052028 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031402, HPA031404, HPA068554 Approved Approved Golgi apparatus
Vesicles
Plasma membrane Expressed in all seminal vesicle: 627.8 -TTC7A KIAA1140, TTC7 ENSG00000068724 Tetratricopeptide repeat domain 7A 2 46916157-47076137 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036781, HPA036782 Approved Mixed testis: 40.8 -IP6K2 IHPK2 ENSG00000068745 Inositol hexakisphosphate kinase 2 3 48688003-48740353 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA007532 Approved Approved Nucleus
Intermediate filaments Expressed in all epididymis: 128.7 -STON1-GTF2A1L SALF ENSG00000068781 STON1-GTF2A1L readthrough 2 48529925-48776517 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA005715 Uncertain Mixed endometrium: 3.6 -SRBD1 FLJ10379 ENSG00000068784 S1 RNA binding domain 1 2 45388680-45612165 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030567, HPA030568 Approved Approved Mitochondria
Cytosol Mixed parathyroid gland: 31.3 -KIF2A HK2, KIF2 ENSG00000068796 Kinesin heavy chain member 2A 5 62306162-62537249 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004715, HPA004716 Approved Validated Nucleus
Nucleoli
Centrosome Expressed in all testis: 91.5 -RASGRP2 CALDAG-GEFI ENSG00000068831 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 11 64726911-64745456 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015667 Approved Tissue enhanced 0 lymph node: 123.6;spleen: 109.0 bone marrow: 94.5 -PSME4 KIAA0077, PA200 ENSG00000068878 Proteasome activator subunit 4 2 53864067-53970840 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060922 Approved Supported Nucleoplasm Expressed in all testis: 77.7 -IFT80 KIAA1374, WDR56 ENSG00000068885 Intraflagellar transport 80 3 160256986-160399880 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035868 Uncertain Expressed in all testis: 45.6 -SIRT2 SIR2L ENSG00000068903 Sirtuin 2 19 38878555-38899862 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004573, HPA011165 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all cerebral cortex: 84.2 -ERLEC1 C2orf30, CL25084, ERLECTIN, XTP3-B, XTP3TPB ENSG00000068912 Endoplasmic reticulum lectin 1 2 53787044-53818819 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031501, HPA031502, HPA031503 Approved Expressed in all thyroid gland: 121.4 -PPP2R5B B56B, FLJ35411, PR61B ENSG00000068971 Protein phosphatase 2, regulatory subunit B', beta 11 64917553-64934473 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036607 Approved Expressed in all cerebral cortex: 59.9 -PYGM ENSG00000068976 Phosphorylase, glycogen, muscle 11 64746389-64760297 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056003 Supported Tissue enriched 32 skeletal muscle: 2832.6 esophagus: 89.5 -PAGE1 CT16.3, GAGE-9, GAGEB1, PAGE-1 ENSG00000068985 P antigen family, member 1 (prostate associated) X 49687450-49695993 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003473 Supported Approved Nucleus
Nucleoli fibrillar center
Mitochondria Tissue enriched 170 testis: 24.9 epididymis: 0.1 -PITX1 BFT, POTX, PTX1 ENSG00000069011 Paired-like homeodomain 1 5 135027735-135034813 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008743 Approved Supported Nucleoli Tissue enriched 5 esophagus: 212.7 salivary gland: 38.8 -TRPC7 ENSG00000069018 Transient receptor potential cation channel, subfamily C, member 7 5 136213320-136365537 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level No evidence Evidence at protein level CAB022592, HPA031126 Uncertain Uncertain Actin filaments
Focal adhesion sites Not detected testis: 0.7 -MAST4 KIAA0303 ENSG00000069020 Microtubule associated serine/threonine kinase family member 4 5 66596361-67169595 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000544 Approved Approved Nucleoplasm
Cytosol Mixed parathyroid gland: 47.3 -ADGRF5 DKFZp564O1923, GPR116, KIAA0758 ENSG00000069122 Adhesion G protein-coupled receptor F5 6 46852512-46954943 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lung: 158.0 adipose tissue: 76.0 -SDK2 FLJ10832, KIAA1514 ENSG00000069188 Sidekick cell adhesion molecule 2 17 73334384-73644089 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014725 Approved Nucleoplasm Tissue enhanced 0 cervix, uterine: 9.0;testis: 18.7 fallopian tube: 3.9 -ADAM7 EAPI, GP-83 ENSG00000069206 ADAM metallopeptidase domain 7 8 24440930-24526970 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008879 Supported Tissue enriched 198 epididymis: 4461.2 seminal vesicle: 22.5 -NUP133 FLJ10814 ENSG00000069248 Nucleoporin 133kDa 1 229440260-229508341 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059767 Approved Supported Nuclear membrane Expressed in all parathyroid gland: 32.5 -NUCKS1 NUCKS ENSG00000069275 Nuclear casein kinase and cyclin-dependent kinase substrate 1 1 205712819-205750276 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062351, HPA063843 Supported Supported Nucleus
Nucleoli Expressed in all cerebral cortex: 179.8 -VPS35 FLJ10752, MEM3, PARK17 ENSG00000069329 VPS35 retromer complex component 16 46656132-46689518 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040802 Supported Supported Endosomes
Lysosomes Mixed parathyroid gland: 16.1 -DNAJA2 CPR3, DNAJ, DNJ3, HIRIP4 ENSG00000069345 DnaJ (Hsp40) homolog, subfamily A, member 2 16 46955362-46973788 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049789, HPA060538 Approved Approved Nucleoli
Intermediate filaments
Cytosol Expressed in all testis: 41.8 -BCL3 BCL4, D19S37 ENSG00000069399 B-cell CLL/lymphoma 3 19 44747705-44760044 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002051, HPA047514 Approved Supported Nucleoplasm
Vesicles
Midbody Expressed in all appendix: 30.9 -KCNAB2 AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B ENSG00000069424 Potassium channel, voltage gated subfamily A regulatory beta subunit 2 1 5991466-6101193 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001975 Approved Tissue enhanced 0 cerebral cortex: 146.3 bone marrow: 74.9 -ABCC9 CMD1O, SUR2 ENSG00000069431 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 12 21797401-21941402 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007279 Uncertain Approved Nucleoplasm
Cytosol Mixed smooth muscle: 34.9 -GAL GAL-GMAP, GALN, GLNN, GMAP ENSG00000069482 Galanin/GMAP prepropeptide 11 68683779-68691175 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049864 Supported Approved Golgi apparatus
Vesicles Tissue enhanced 0 appendix: 18.7;smooth muscle: 11.9 colon: 5.3 -CLEC2D CLAX, LLT1, OCIL ENSG00000069493 C-type lectin domain family 2, member D 12 9664969-9699555 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA017649, HPA047584 Uncertain Approved Nucleoplasm
Golgi apparatus Tissue enhanced 0 lymph node: 64.2 tonsil: 39.5 -FUNDC1 MGC51029 ENSG00000069509 FUN14 domain containing 1 X 44523639-44543001 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038773 Uncertain Expressed in all cerebral cortex: 30.7 -MAOB ENSG00000069535 Monoamine oxidase B X 43766611-43882447 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002328, CAB037200 Supported Approved Nucleoli
Mitochondria Mixed seminal vesicle: 213.0 -RORA NR1F1, ROR1, ROR2, ROR3, RZRA ENSG00000069667 RAR-related orphan receptor A 15 60488284-61229319 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level CAB009861 Approved Expressed in all skin: 76.4 -DRD4 ENSG00000069696 Dopamine receptor D4 11 637293-640706 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected skin: 0.3 -TGFBR3 betaglycan, BGCAN ENSG00000069702 Transforming growth factor, beta receptor III 1 91680343-91906335 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008257, CAB018971 Supported Approved Cytosol Expressed in all ovary: 99.5 -KIAA1107 ENSG00000069712 KIAA1107 1 92167052-92184723 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA024216, HPA027327 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 47.0 testis: 13.4 -PLA2G10 GXPLA2 ENSG00000069764 Phospholipase A2, group X 16 14672545-14694669 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041893 Uncertain Tissue enhanced 0 colon: 7.1;rectum: 6.7;stomach: 10.5 duodenum: 2.2 -HES2 bHLHb40 ENSG00000069812 Hes family bHLH transcription factor 2 1 6412418-6424670 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039462 Uncertain Tissue enhanced 0 skin: 17.0 placenta: 9.8 -ATP1B3 CD298, FLJ29027 ENSG00000069849 ATPase, Na+/K+ transporting, beta 3 polypeptide 3 141876124-141926514 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020697, HPA048963 Supported Supported Plasma membrane Expressed in all skin: 310.5 -NEDD4 KIAA0093, MGC176705, NEDD4-1, RPF1 ENSG00000069869 Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 15 55826922-55993746 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB001991, HPA039883, CAB072833 Approved Approved Cytosol Mixed placenta: 22.3 -PIGB ENSG00000069943 Phosphatidylinositol glycan anchor biosynthesis, class B 15 55318960-55355648 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039929 Uncertain Uncertain Plasma membrane
Cytosol Mixed parathyroid gland: 22.8 -MAPK6 ERK3, HsT17250, p97MAPK, PRKM6 ENSG00000069956 Mitogen-activated protein kinase 6 15 51952106-52067372 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005184, HPA030262 Approved Validated Cytosol Expressed in all testis: 52.7 -GNB5 GB5 ENSG00000069966 Guanine nucleotide binding protein (G protein), beta 5 15 52115105-52191369 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB032353, HPA041942, HPA044198 Uncertain Approved Nuclear speckles
Centrosome
Rods & Rings Mixed parathyroid gland: 73.1 -RAB27A GS2, HsT18676, RAB27, RAM ENSG00000069974 RAB27A, member RAS oncogene family 15 55202966-55319113 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001333, CAB034046 Approved Mixed stomach: 115.4 -CECR5 ENSG00000069998 Cat eye syndrome chromosome region, candidate 5 22 17137511-17165287 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005548 Approved Approved Mitochondria Expressed in all duodenum: 27.4 -UFD1L UFD1 ENSG00000070010 Ubiquitin fusion degradation 1 like (yeast) 22 19449910-19479215 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030287, HPA030288, HPA073425 Approved Validated Endoplasmic reticulum Expressed in all testis: 64.5 -LRP6 ADCAD2 ENSG00000070018 Low density lipoprotein receptor-related protein 6 12 12116025-12267012 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004490, HPA029925 Supported Mixed parathyroid gland: 16.2 -GUCY2C GUC2C, STAR ENSG00000070019 Guanylate cyclase 2C 12 14612632-14696585 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037655, HPA073759 Uncertain Uncertain Vesicles Group enriched 13 colon: 38.4;duodenum: 70.6;rectum: 48.1;small intestine: 74.7 appendix: 4.5 -SCT ENSG00000070031 Secretin 11 626431-627143 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA050961 Supported Group enriched 6 duodenum: 35.9;small intestine: 8.0 spleen: 3.5 -PHRF1 KIAA1542, PPP1R125, RNF221 ENSG00000070047 PHD and ring finger domains 1 11 576486-612222 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019867, HPA062933 Uncertain Mixed endometrium: 4.5 -IKBKAP DYS, ELP1, IKAP, IKI3, TOT1 ENSG00000070061 Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 9 108867517-108934116 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021340, HPA049677, HPA050686 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 74.9 -NUCB2 NEFA ENSG00000070081 Nucleobindin 2 11 17208153-17349974 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA008395, CAB015931 Approved Validated Golgi apparatus Expressed in all parathyroid gland: 719.8 -PFN2 ENSG00000070087 Profilin 2 3 149964904-150050788 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035611, CAB037073 Supported Expressed in all cerebral cortex: 420.7 -PTPN3 PTPH1 ENSG00000070159 Protein tyrosine phosphatase, non-receptor type 3 9 109375466-109498313 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038343, HPA046728 Approved Mixed skin: 35.9 -SPTB ENSG00000070182 Spectrin, beta, erythrocytic 14 64746283-64879883 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003394, HPA003398, CAB015169, CAB016232 Supported Uncertain Golgi apparatus
Cytosol Tissue enhanced 0 bone marrow: 38.3;skeletal muscle: 43.1 heart muscle: 15.1 -DAPP1 BAM32 ENSG00000070190 Dual adaptor of phosphotyrosine and 3-phosphoinositides 4 99816833-99870154 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033822, HPA046074 Approved Mixed lymph node: 51.8 -FGF10 ENSG00000070193 Fibroblast growth factor 10 5 44303544-44389706 Disease related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB010315 Uncertain Tissue enhanced 0 ovary: 41.8 adipose tissue: 17.3 -SLC44A1 CD92, CDW92, CHTL1, CTL1 ENSG00000070214 Solute carrier family 44 (choline transporter), member 1 9 105244622-105439171 CD markers, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064714 Supported Nucleoplasm
Mitochondria Expressed in all cerebral cortex: 107.8 -TMEM260 C14orf101, FLJ20392 ENSG00000070269 Transmembrane protein 260 14 56488354-56650606 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003502 Uncertain Approved Nucleus
Focal adhesion sites
Cytosol Tissue enhanced 0 cervix, uterine: 63.2 thyroid gland: 14.0 -SMG6 C17orf31, EST1A, KIAA0732, SMG-6 ENSG00000070366 SMG6 nonsense mediated mRNA decay factor 17 2059839-2303771 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042932 Approved Supported Nucleoli
Cytosol Expressed in all ovary: 47.4 -EXOC5 SEC10, SEC10L1, SEC10P ENSG00000070367 Exocyst complex component 5 14 57200507-57269008 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060837 Approved Mixed testis: 20.7 -CLTCL1 CHC22, CLH22, CLTCL, CLTD ENSG00000070371 Clathrin, heavy chain-like 1 22 19179473-19291716 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA075795 Approved Vesicles Tissue enhanced 0 skeletal muscle: 24.1;testis: 49.4 bone marrow: 10.5 -FGF22 ENSG00000070388 Fibroblast growth factor 22 19 639879-644371 Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 8.5 cerebral cortex: 2.1 -FSTL3 FLRG, FSRP ENSG00000070404 Follistatin-like 3 (secreted glycoprotein) 19 676365-683399 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB024899, HPA045378 Approved Approved Nucleoplasm Expressed in all placenta: 259.7 -DGCR2 DGS-C, IDD, KIAA0163, LAN, SEZ-12 ENSG00000070413 DiGeorge syndrome critical region gene 2 22 19036282-19122454 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000873, HPA075929 Uncertain Approved Nucleoplasm
Nuclear bodies Expressed in all cerebral cortex: 58.4 -RNF126 FLJ20552 ENSG00000070423 Ring finger protein 126 19 647526-663277 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043050 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 38.3 -MNT bHLHd3, MAD6, MXD6, ROX ENSG00000070444 MAX network transcriptional repressor 17 2384060-2401118 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059532, HPA067578 Validated Nucleoplasm Expressed in all cerebral cortex: 15.3 -ZXDC FLJ13861, MGC11349 ENSG00000070476 ZXD family zinc finger C 3 126437601-126475919 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA049593 Supported Nucleoli
Vesicles Expressed in all bone marrow: 25.5 -JMJD6 KIAA0585, PTDSR, PTDSR1 ENSG00000070495 Jumonji domain containing 6 17 76712832-76726799 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004548, HPA059156 Supported Supported Nucleoplasm Expressed in all bone marrow: 81.1 -POLB ENSG00000070501 Polymerase (DNA directed), beta 8 42338454-42371808 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011616, HPA049104 Supported Approved Vesicles Expressed in all testis: 92.3 -ST6GALNAC1 SIAT7A, ST6GalNAcI ENSG00000070526 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 17 76624761-76643838 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014975 Uncertain Tissue enhanced 0 colon: 166.2;rectum: 239.7 cervix: 90.8 -WIPI1 Atg18, ATG18A, FLJ10055, WIPI49 ENSG00000070540 WD repeat domain, phosphoinositide interacting 1 17 68420948-68457513 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007493, CAB037230 Supported Expressed in all placenta: 89.4 -FRMPD1 FRMD2, KIAA0967 ENSG00000070601 FERM and PDZ domain containing 1 9 37651000-37746904 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042934 Uncertain Tissue enhanced 0 testis: 14.3 skin: 7.9 -GBA2 AD035, DKFZp762K054, KIAA1605, SPG46 ENSG00000070610 Glucosidase, beta (bile acid) 2 9 35736866-35749228 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024026 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all small intestine: 65.5 -NDST1 HSST, NST1 ENSG00000070614 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 5 150485818-150558211 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060532 Approved Expressed in all spleen: 60.7 -ASNS ENSG00000070669 Asparagine synthetase (glutamine-hydrolyzing) 7 97852118-97872542 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004924, HPA029318, HPA064737 Approved Validated Cytosol Expressed in all cerebral cortex: 74.3 -AP3M2 AP47B, CLA20 ENSG00000070718 Adaptor-related protein complex 3, mu 2 subunit 8 42152946-42171673 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB014876, HPA045591, HPA048380 Approved Expressed in all cerebral cortex: 47.0 -CNGB1 CNCG2, CNCG3L, CNGB1B, GAR1, GARP, RCNC2, RCNCb, RP45 ENSG00000070729 Cyclic nucleotide gated channel beta 1 16 57882340-57971116 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039159, HPA060355 Uncertain Approved Vesicles
Cytosol Mixed appendix: 1.6 -ST6GALNAC2 SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM ENSG00000070731 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 17 76563710-76586956 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048849 Uncertain Expressed in all fallopian tube: 77.3 -CHAT ENSG00000070748 Choline O-acetyltransferase 10 49609095-49665104 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002313, HPA048547 Supported Tissue enriched 11 placenta: 7.1 duodenum: 0.6 -PABPC1 PAB1, PABP1, PABPC2, PABPL1 ENSG00000070756 Poly(A) binding protein, cytoplasmic 1 8 100685816-100722809 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011536, HPA045423, HPA067156 Supported Supported Cytosol Expressed in all esophagus: 1155.5 -TESK2 ENSG00000070759 Testis-specific kinase 2 1 45343883-45491166 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027257, HPA063869 Uncertain Validated Nucleoplasm Mixed prostate: 25.8 -CFAP20 C16orf80, fSAP23, GTL3 ENSG00000070761 Cilia and flagella associated protein 20 16 58113588-58129450 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018195 Uncertain Supported Nucleus Expressed in all fallopian tube: 53.8 -CSNK2A2 CSNK2A1 ENSG00000070770 Casein kinase 2, alpha prime polypeptide 16 58157907-58197920 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077719 Approved Nucleoplasm
Vesicles
Cytosol Expressed in all testis: 236.7 -PTPN21 PTPD1, PTPRL10 ENSG00000070778 Protein tyrosine phosphatase, non-receptor type 21 14 88465778-88554733 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB011468, HPA049110 Approved Uncertain Nuclear bodies Mixed skin: 34.5 -EIF2B3 EIF-2B, EIF2Bgamma ENSG00000070785 Eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1 44850522-44986722 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024213, HPA024218, HPA024219 Supported Supported Vesicles
Cytosol Expressed in all parathyroid gland: 48.6 -CAMK2A CAMKA, CaMKIINalpha, KIAA0968 ENSG00000070808 Calcium/calmodulin-dependent protein kinase II alpha 5 150219491-150290291 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004330, HPA051783, HPA051785, HPA053973 Supported Supported Plasma membrane
Cell Junctions Tissue enriched 9 cerebral cortex: 284.4 skeletal muscle: 33.3 -TCOF1 TCS, treacle ENSG00000070814 Treacher Collins-Franceschetti syndrome 1 5 150357639-150400308 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033199, HPA038237, HPA038238 Supported Validated Nucleus
Nucleoli fibrillar center Expressed in all lymph node: 22.3 -CDC42 CDC42Hs, G25K ENSG00000070831 Cell division cycle 42 1 22052627-22092946 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004360 Approved Validated Microtubules
Cytokinetic bridge Expressed in all bone marrow: 253.0 -OSBPL3 KIAA0704, ORP-3, ORP3, OSBP3 ENSG00000070882 Oxysterol binding protein-like 3 7 24796539-24981634 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000691, HPA048401 Approved Supported Nucleoli
Cytosol Mixed parathyroid gland: 33.0 -EPHA8 EEK, Hek3 ENSG00000070886 EPH receptor A8 1 22563564-22603594 Cancer-related genes, Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB009660, HPA031433 Uncertain Tissue enhanced 0 adrenal gland: 4.9;spleen: 2.7;testis: 1.9 cerebral cortex: 1.3 -SLC12A3 NCCT ENSG00000070915 Solute carrier family 12 (sodium/chloride transporter), member 3 16 56865207-56915850 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028748 Supported Tissue enriched 107 kidney: 109.3 lymph node: 1.0 -RAD18 RNF73 ENSG00000070950 RAD18 E3 ubiquitin protein ligase 3 8775402-8963773 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006716, HPA006724, HPA008752 Supported Approved Validated Nucleoplasm
Nuclear bodies Mixed duodenum: 10.5 -ATP2B1 PMCA1 ENSG00000070961 ATPase, Ca++ transporting, plasma membrane 1 12 89588049-89709300 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005605, HPA011166, HPA012945 Supported Supported Plasma membrane Expressed in all cerebral cortex: 144.0 -TRPM5 LTRPC5, MTR1 ENSG00000070985 Transient receptor potential cation channel, subfamily M, member 5 11 2404515-2423045 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042115, HPA043315 Approved Group enriched 5 colon: 1.0;duodenum: 3.0;epididymis: 2.2;seminal vesicle: 2.5;small intestine: 2.9 thyroid gland: 0.4 -NCK2 NCKbeta ENSG00000071051 NCK adaptor protein 2 2 105744897-105894274 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB016116, HPA031004 Approved Expressed in all small intestine: 59.5 -MAP4K4 FLH21957, HGK, NIK ENSG00000071054 Mitogen-activated protein kinase kinase kinase kinase 4 2 101696850-101894689 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008476 Uncertain Expressed in all cerebral cortex: 155.0 -MGAT4A GnT-4a, GnT-Iva ENSG00000071073 Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 2 98619106-98731126 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007608 Supported Approved Golgi apparatus Mixed parathyroid gland: 82.4 -RPL31 L31 ENSG00000071082 Ribosomal protein L31 2 101001715-101024032 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072263 Approved Expressed in all ovary: 5517.7 -WDR1 ENSG00000071127 WD repeat domain 1 4 10074339-10116949 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020804, HPA036434, HPA058132 Approved Validated Cytosol Expressed in all smooth muscle: 305.5 -SNX13 KIAA0713, RGS-PX1 ENSG00000071189 Sorting nexin 13 7 17790761-17940501 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 31.7 -MS4A12 FLJ20217, Ms4a10 ENSG00000071203 Membrane-spanning 4-domains, subfamily A, member 12 11 60492778-60507430 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA057657 Supported Group enriched 19 colon: 239.6;rectum: 284.9 appendix: 14.0 -ARHGAP10 FLJ20896, FLJ41791, GRAF2 ENSG00000071205 Rho GTPase activating protein 10 4 147732063-148072780 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039589 Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all parathyroid gland: 43.4 -RPS6KA2 HU-2, RSK, RSK3 ENSG00000071242 Ribosomal protein S6 kinase, 90kDa, polypeptide 2 6 166409364-166906451 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026243, HPA045061, HPA054237, CAB069428 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 73.0 -ING3 Eaf4, FLJ20089, MEAF4, p47ING3 ENSG00000071243 Inhibitor of growth family, member 3 7 120950749-120977216 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067388, HPA067575 Approved Supported Nucleus Expressed in all bone marrow: 50.4 -VASH1 KIAA1036 ENSG00000071246 Vasohibin 1 14 76762189-76783015 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000653 Uncertain Expressed in all cerebral cortex: 34.5 -LMCD1 ENSG00000071282 LIM and cysteine-rich domains 1 3 8501707-8574673 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024059 Approved Supported Nucleus
Plasma membrane
Cell Junctions
Cytosol Mixed skeletal muscle: 201.9 -WBSCR22 MERM1, MGC19709, MGC2022, MGC5140, PP3381, WBMT ENSG00000071462 Williams Beuren syndrome chromosome region 22 7 73683025-73705161 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052185 Approved Supported Nucleus
Nucleoli Expressed in all testis: 207.5 -SEL1L IBD2, SEL1L1 ENSG00000071537 Sel-1 suppressor of lin-12-like (C. elegans) 14 81471549-81533861 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024267 Approved Expressed in all thyroid gland: 90.3 -TRIP13 16E1BP ENSG00000071539 Thyroid hormone receptor interactor 13 5 892643-919357 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005727, HPA053093 Approved Approved Nucleus Tissue enriched 5 testis: 53.1 fallopian tube: 10.5 -ATP6AP1 16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3 ENSG00000071553 ATPase, H+ transporting, lysosomal accessory protein 1 X 154428632-154436516 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB015218 Uncertain Approved Plasma membrane
Microtubules
Cytosol Expressed in all parathyroid gland: 205.5 -TCF3 bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, VDIR ENSG00000071564 Transcription factor 3 19 1609290-1652605 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018351, HPA049808, HPA062476 Approved Validated Nucleoplasm Expressed in all lymph node: 104.6 -TRIB2 GS3955, TRB2 ENSG00000071575 Tribbles pseudokinase 2 2 12716889-12742734 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA001305 Approved Approved Nucleoplasm
Cytosol Expressed in all ovary: 116.8 -DAZAP1 MGC19907 ENSG00000071626 DAZ associated protein 1 19 1407569-1435687 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004201, HPA004631 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 103.0 -MBD3 ENSG00000071655 Methyl-CpG binding domain protein 3 19 1573596-1592801 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013265 Supported Supported Nucleoplasm Expressed in all placenta: 45.7 -PRLH PRH ENSG00000071677 Prolactin releasing hormone 2 237566574-237567175 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014768 Uncertain Not detected heart muscle: 0.8 -HLTF HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3 ENSG00000071794 Helicase-like transcription factor 3 149030127-149086554 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015284, HPA049001 Uncertain Validated Nucleus Expressed in all testis: 83.0 -FAM50A 9F, DXS9928E, HXC-26, XAP5 ENSG00000071859 Family with sequence similarity 50, member A X 154444126-154450654 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003585 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 66.2 -FAM3A 2-19, DXS560S, XAP-7 ENSG00000071889 Family with sequence similarity 3, member A X 154506159-154516242 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025016, HPA056991 Uncertain Approved Nucleus
Nucleoli Expressed in all small intestine: 28.9 -CPSF1 ENSG00000071894 Cleavage and polyadenylation specific factor 1, 160kDa 8 144393229-144409349 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065167, HPA068906 Approved Nucleoplasm Expressed in all testis: 63.6 -MYO3B ENSG00000071909 Myosin IIIB 2 170178145-170655171 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015745, HPA045483 Uncertain Group enriched 5 epididymis: 11.2;kidney: 4.6;parathyroid gland: 14.8;urinary bladder: 4.3 thyroid gland: 1.6 -CYBRD1 CYB561A2, DCYTB, FLJ23462, FRRS3 ENSG00000071967 Cytochrome b reductase 1 2 171522247-171558133 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014757, HPA056736 Approved Approved Golgi apparatus
Cytosol Expressed in all thyroid gland: 379.4 -CDH19 CDH7 ENSG00000071991 Cadherin 19, type 2 18 66501083-66604138 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056332 Uncertain Mixed heart muscle: 9.6 -PDCD2 RP8, ZMYND7 ENSG00000071994 Programmed cell death 2 6 170575295-170584692 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026713, HPA075534 Uncertain Approved Nucleoplasm
Cytokinetic bridge Expressed in all thyroid gland: 59.8 -SLC6A15 FLJ10316, hv7-3, NTT73, SBAT1, V7-3 ENSG00000072041 Solute carrier family 6 (neutral amino acid transporter), member 15 12 84859488-84913615 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008609 Uncertain Approved Nucleoli
Vesicles Tissue enhanced 0 cerebral cortex: 23.1 placenta: 5.5 -RDH11 ARSDR1, MDT1, SDR7C1 ENSG00000072042 Retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 14 67676801-67695814 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046011 Supported Tissue enriched 8 prostate: 945.5 parathyroid gland: 123.3 -PRKACA PKACa ENSG00000072062 Protein kinase, cAMP-dependent, catalytic, alpha 19 14091688-14118084 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010361, HPA071185 Approved Approved Cytosol Expressed in all heart muscle: 203.1 -ADGRL1 CIRL1, KIAA0821, LEC2, LPHN1 ENSG00000072071 Adhesion G protein-coupled receptor L1 19 14147743-14206187 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037974 Uncertain Tissue enhanced 0 cerebral cortex: 60.3 parathyroid gland: 24.2 -SPP2 SPP24 ENSG00000072080 Secreted phosphoprotein 2, 24kDa 2 234050679-234077134 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 2165 liver: 264.2 testis: 0.1 -ACTN1 ENSG00000072110 Actinin, alpha 1 14 68874143-68979440 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004303, HPA006035 Approved Validated Plasma membrane
Focal adhesion sites Expressed in all smooth muscle: 744.4 -ZFYVE26 KIAA0321, SPG15 ENSG00000072121 Zinc finger, FYVE domain containing 26 14 67727374-67816590 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055500 Approved Mixed parathyroid gland: 14.4 -RPS6KA6 RSK4 ENSG00000072133 Ribosomal protein S6 kinase, 90kDa, polypeptide 6 X 84058346-84187907 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002852, HPA003904 Uncertain Supported Nucleus
Nucleoli
Mitochondria Tissue enhanced 0 parathyroid gland: 18.6;thyroid gland: 21.8 kidney: 8.8 -EPN2 EHB21, KIAA1065 ENSG00000072134 Epsin 2 17 19215615-19336715 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049809, HPA053360 Approved Supported Vesicles Expressed in all cerebral cortex: 95.3 -PTPN18 BDP1 ENSG00000072135 Protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 2 130356007-130375409 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB012174 Uncertain Expressed in all lymph node: 48.0 -LIMS2 ENSG00000072163 LIM and senescent cell antigen-like domains 2 2 127638381-127681786 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058340 Approved Supported Focal adhesion sites Mixed seminal vesicle: 135.8 -ASIC4 ACCN4, BNAC4 ENSG00000072182 Acid sensing (proton gated) ion channel family member 4 2 219514170-219538772 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036042 Approved Golgi apparatus Tissue enriched 8 cerebral cortex: 10.6 adrenal gland: 1.3 -SPEG APEG1, BPEG, KIAA1297, MGC12676, SPEGalpha, SPEGbeta ENSG00000072195 SPEG complex locus 2 219434846-219498287 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018904 Approved Approved Vesicles Mixed skeletal muscle: 43.3 -LNX1 LNX, MPDZ, PDZRN2 ENSG00000072201 Ligand of numb-protein X 1, E3 ubiquitin protein ligase 4 53459301-53701405 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA002235, HPA071091 Approved Supported Cell Junctions
Cytosol Mixed placenta: 41.1 -ALDH3A2 ALDH10, ALDH3A2, FALDH , SLS ENSG00000072210 Aldehyde dehydrogenase 3 family, member A2 17 19648136-19677598 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014769, CAB020692 Approved Expressed in all adrenal gland: 179.9 -TFRC CD71, p90, TFR1 ENSG00000072274 Transferrin receptor 3 196027183-196082189 Cancer-related genes, CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000153, HPA028598 Supported Supported Endosomes
Lysosomes Expressed in all bone marrow: 157.6 -SREBF1 bHLHd1, SREBP-1c, SREBP1 ENSG00000072310 Sterol regulatory element binding transcription factor 1 17 17810399-17837002 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005406, HPA043343, HPA043878 Uncertain Supported Golgi apparatus
Cytosol Expressed in all adrenal gland: 92.9 -TRPC5 PPP1R159 ENSG00000072315 Transient receptor potential cation channel, subfamily C, member 5 X 111774315-112082776 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 1.9 liver: 0.4 -AFF4 AF5Q31, MCEF ENSG00000072364 AF4/FMR2 family, member 4 5 132875379-132963634 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023690, HPA029634 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all parathyroid gland: 73.0 -UBE2D1 E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A ENSG00000072401 Ubiquitin-conjugating enzyme E2D 1 10 58334975-58370753 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003920 Approved Approved Plasma membrane
Cytosol Expressed in all skeletal muscle: 47.8 -MPP5 FLJ12615, PALS1 ENSG00000072415 Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 14 67241109-67335819 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000993 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Expressed in all thyroid gland: 44.4 -RHOBTB1 KIAA0740 ENSG00000072422 Rho-related BTB domain containing 1 10 60869438-61001440 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA040205, HPA040226 Approved Approved Nucleoplasm
Cytosol Mixed placenta: 52.1 -SMC1A DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb ENSG00000072501 Structural maintenance of chromosomes 1A X 53374149-53422728 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005499, CAB025404 Supported Validated Nucleoplasm
Cytosol Expressed in all parathyroid gland: 51.8 -HSD17B10 17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1 ENSG00000072506 Hydroxysteroid (17-beta) dehydrogenase 10 X 53431258-53434373 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001432 Approved Expressed in all liver: 126.2 -MARK2 EMK1, PAR-1, PAR-1B, Par1b ENSG00000072518 MAP/microtubule affinity-regulating kinase 2 11 63838928-63911019 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038790, HPA074905 Approved Supported Nucleoplasm
Plasma membrane Expressed in all skin: 46.2 -HMMR CD168, RHAMM ENSG00000072571 Hyaluronan-mediated motility receptor (RHAMM) 5 163460203-163491945 CD markers, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002433, HPA040025, HPA043926, HPA061524 Approved Validated Microtubules
Centrosome
Cytosol Tissue enhanced 0 testis: 50.3 lymph node: 21.9 -CHFR FLJ10796, RNF196 ENSG00000072609 Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 12 132822187-132956304 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045768 Uncertain Nuclear bodies
Microtubules Expressed in all testis: 22.8 -TRHDE PAP-II, PGPEP2, TRH-DE ENSG00000072657 Thyrotropin-releasing hormone degrading enzyme 12 72087266-72670757 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed cerebral cortex: 8.0 -P4HA2 C-P4Halpha(II) ENSG00000072682 Prolyl 4-hydroxylase, alpha polypeptide II 5 132191838-132295315 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016997, HPA027824, CAB062557 Supported Validated Endoplasmic reticulum
Vesicles Expressed in all epididymis: 93.7 -FCGR2B CD32, CD32B, FCG2, FCGR2 ENSG00000072694 Fc fragment of IgG, low affinity IIb, receptor (CD32) 1 161663147-161678654 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007796, HPA014730 Supported Tissue enriched 16 placenta: 571.2 adipose tissue: 36.3 -NFATC3 NFAT4, NFATX ENSG00000072736 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 16 68084751-68229259 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004514, HPA023844, HPA050665 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 49.9 -TRNT1 CCA1, CGI-47, MtCCA ENSG00000072756 TRNA nucleotidyl transferase, CCA-adding, 1 3 3126916-3150879 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036938 Uncertain Validated Mitochondria Expressed in all prostate: 26.1 -ACADVL ACAD6, LCACD, VLCAD ENSG00000072778 Acyl-CoA dehydrogenase, very long chain 17 7217125-7225273 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019006, HPA020595 Supported Supported Nucleus
Nucleoli
Mitochondria Expressed in all adrenal gland: 455.8 -STK10 LOK, PRO2729 ENSG00000072786 Serine/threonine kinase 10 5 172042073-172188386 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015083, CAB020840 Supported Expressed in all spleen: 62.1 -FBXW11 BTRC2, BTRCP2, Fbw11, Fbw1b, FBXW1B, Hos, KIAA0696 ENSG00000072803 F-box and WD repeat domain containing 11 5 171861549-172006873 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062578, HPA072204 Approved Approved Nucleoli
Vesicles Expressed in all parathyroid gland: 71.3 -ACAP1 CENTB1, KIAA0050 ENSG00000072818 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 17 7336529-7351478 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062130 Approved Vesicles Tissue enhanced 0 lymph node: 95.5 spleen: 71.2 -CRMP1 DPYSL1, DRP-1 ENSG00000072832 Collapsin response mediator protein 1 4 5748084-5893058 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035640, CAB037313 Approved Supported Cytosol Tissue enriched 5 cerebral cortex: 134.1 endometrium: 26.8 -EVC DWF-1 ENSG00000072840 Ellis van Creveld protein 4 5711197-5814305 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008703, HPA016046 Uncertain Approved Nucleoplasm
Cytosol Mixed ovary: 41.3 -DERL2 CGI-101, derlin-2, F-LAN-1, F-LANa, FLANa ENSG00000072849 Derlin 2 17 5471251-5486811 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037287, HPA048957, HPA056551 Supported Supported Endoplasmic reticulum Expressed in all thyroid gland: 41.3 -SIDT1 FLJ20174, SID-1 ENSG00000072858 SID1 transmembrane family, member 1 3 113532296-113629578 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035862 Approved Mixed rectum: 10.7 -NDE1 FLJ20101, NDE, nudE ENSG00000072864 NudE neurodevelopment protein 1 16 15643267-15726353 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024075 Approved Mixed lymph node: 15.0 -MRVI1 IRAG, JAW1L ENSG00000072952 Murine retrovirus integration site 1 homolog 11 10573091-10693988 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008704 Uncertain Approved Nuclear bodies
Cytosol Mixed endometrium: 98.6 -TMEM38A MGC3169, TRIC-A ENSG00000072954 Transmembrane protein 38A 19 16661127-16690029 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048100, HPA050463 Supported Approved Nucleus Tissue enriched 9 skeletal muscle: 199.8 cerebral cortex: 23.2 -AP1M1 AP47, CLAPM2 ENSG00000072958 Adaptor-related protein complex 1, mu 1 subunit 19 16197578-16245907 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045256 Uncertain Expressed in all testis: 96.4 -PVR CD155, HVED, Necl-5, NECL5, PVS, Tage4 ENSG00000073008 Poliovirus receptor 19 44643798-44663583 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012568 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Expressed in all placenta: 16.9 -XRCC1 RCC ENSG00000073050 X-ray repair complementing defective repair in Chinese hamster cells 1 19 43543040-43580473 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005427, HPA006717 Supported Validated Nucleoplasm Expressed in all ovary: 34.6 -SCARB1 CD36L1, CLA-1, CLA1, SR-BI, SRB1 ENSG00000073060 Scavenger receptor class B, member 1 12 124776856-124882668 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066285, CAB070124 Supported Approved Vesicles Group enriched 7 adrenal gland: 762.1;placenta: 284.3 liver: 71.6 -CYP2W1 FLJ20359, MGC34287 ENSG00000073067 Cytochrome P450, family 2, subfamily W, polypeptide 1 7 983199-989640 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012753 Uncertain Tissue enhanced 0 adrenal gland: 5.6;duodenum: 6.3;skin: 9.7 placenta: 1.4 -MCM2 BM28, CCNL1, cdc19, CDCL1, D3S3194, KIAA0030 ENSG00000073111 Minichromosome maintenance complex component 2 3 127598223-127622436 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000303, HPA031495, HPA031496 Supported Validated Nucleoplasm
Cytosol Mixed bone marrow: 38.6 -MOV10L1 CHAMP, DJ402G11.8, DKFZp434B0717 ENSG00000073146 Mov10 RISC complex RNA helicase like 1 22 50089879-50161690 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA019034 Approved Tissue enriched 10 testis: 40.0 endometrium: 4.2 -PANX2 hPANX2, PX2 ENSG00000073150 Pannexin 2 22 50170731-50180294 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA004624, HPA039117 Approved Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 8.7 seminal vesicle: 2.1 -SELO ENSG00000073169 Selenoprotein O 22 50200979-50217616 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all skin: 9.3 -TP63 EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L ENSG00000073282 Tumor protein p63 3 189631416-189897279 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000083, HPA006288, HPA007010 Supported Validated Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced 0 esophagus: 61.1;skin: 164.8 urinary bladder: 29.9 -ALPK1 FLJ22670, KIAA1527, Lak ENSG00000073331 Alpha-kinase 1 4 112285509-112442620 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027435, HPA027443 Approved Approved Centrosome Mixed parathyroid gland: 9.2 -LLGL2 HGL, Hugl-2 ENSG00000073350 Lethal giant larvae homolog 2 (Drosophila) 17 75525080-75575208 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022913 Uncertain Supported Vesicles
Cytosol Mixed stomach: 64.0 -PDE8A HsT19550 ENSG00000073417 Phosphodiesterase 8A 15 84980440-85139145 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007722 Approved Approved Golgi apparatus Expressed in all parathyroid gland: 29.6 -CLCN4 ClC-4, CLC4 ENSG00000073464 Chloride channel, voltage-sensitive 4 X 10156945-10237660 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031313, HPA063637 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 49.2;epididymis: 27.6 skeletal muscle: 14.6 -NLE1 FLJ10458 ENSG00000073536 Notchless homolog 1 (Drosophila) 17 35128753-35142315 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018807 Approved Supported Nucleus
Nucleoli Expressed in all ovary: 15.8 -SDHA FP, SDH2, SDHF ENSG00000073578 Succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 5 218241-256700 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034929, HPA041981, HPA064582 Supported Validated Mitochondria Expressed in all heart muscle: 249.5 -SMARCE1 BAF57 ENSG00000073584 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 17 40624962-40648508 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003916, CAB037318 Supported Supported Nucleoplasm Expressed in all endometrium: 72.9 -FNDC8 DKFZp434H2215 ENSG00000073598 Fibronectin type III domain containing 8 17 35121579-35130732 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA026521 Supported Tissue enriched 391 testis: 107.9 parathyroid gland: 0.2 -GSDMB GSDML, PRO2521 ENSG00000073605 Gasdermin B 17 39904595-39919854 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB013681, HPA023925, HPA052407 Supported Tissue enhanced 0 duodenum: 68.8;small intestine: 86.7 rectum: 63.5 -KDM5A JARID1A, RBBP2 ENSG00000073614 Lysine (K)-specific demethylase 5A 12 280129-389454 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006201 Approved Nuclear bodies
Cytosol Expressed in all testis: 42.5 -ADAM11 MDC ENSG00000073670 ADAM metallopeptidase domain 11 17 44759031-44781846 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 19.8 heart muscle: 4.5 -PPP2R3A PPP2R3 ENSG00000073711 Protein phosphatase 2, regulatory subunit B'', alpha 3 135965673-136147891 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035829, HPA035830, HPA065338 Uncertain Approved Golgi apparatus Tissue enhanced 0 skeletal muscle: 63.3 heart muscle: 33.3 -FERMT2 KIND2, mig-2, PLEKHC1, UNC112B ENSG00000073712 Fermitin family member 2 14 52857268-52952435 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040505 Uncertain Supported Nucleoplasm
Focal adhesion sites Mixed smooth muscle: 220.5 -ABCB11 ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP ENSG00000073734 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2 168922938-169031322 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019035 Supported Uncertain Nucleoplasm
Plasma membrane
Cytosol Tissue enriched 13 liver: 19.1 testis: 1.4 -DHRS9 3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4 ENSG00000073737 Dehydrogenase/reductase (SDR family) member 9 2 169064789-169096167 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036491, HPA036667 Approved Tissue enhanced 0 colon: 67.6;rectum: 48.8 esophagus: 30.3 -CD5L API6, Spalpha ENSG00000073754 CD5 molecule-like 1 157830914-157898256 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065686, HPA068384 Supported Tissue enriched 15 spleen: 800.2 liver: 54.4 -PTGS2 COX2 ENSG00000073756 Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1 186671791-186680427 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000113, HPA001335 Approved Supported Endoplasmic reticulum Tissue enhanced 0 seminal vesicle: 178.8 cervix: 98.8 -IGF2BP2 IMP-2 ENSG00000073792 Insulin-like growth factor 2 mRNA binding protein 2 3 185643739-185825056 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017126, HPA035145 Approved Validated Cytosol Mixed placenta: 21.0 -MAP3K13 LZK, MEKK13 ENSG00000073803 Mitogen-activated protein kinase kinase kinase 13 3 185282941-185489097 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA016497, HPA036691, HPA036692 Uncertain Approved Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all epididymis: 68.4 -ST6GAL1 SIAT1 ENSG00000073849 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 3 186930485-187078553 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015018, CAB016122 Supported Expressed in all liver: 271.6 -TBX21 T-bet, TBLYM ENSG00000073861 T-box 21 17 47733244-47746119 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB009524, CAB030043 Supported Tissue enhanced 0 lymph node: 8.6;spleen: 11.2 bone marrow: 6.4 -FRY 13CDNA73, bA37E23.1, C13orf14, CG003 ENSG00000073910 Furry homolog (Drosophila) 13 32031300-32299122 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041635 Approved Expressed in all heart muscle: 32.0 -PICALM CALM, CLTH ENSG00000073921 Phosphatidylinositol binding clathrin assembly protein 11 85957684-86069882 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019053, HPA019061 Supported Supported Vesicles Expressed in all parathyroid gland: 291.7 -NSF SKD2 ENSG00000073969 N-ethylmaleimide-sensitive factor 17 46590669-46757464 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003154, CAB009324, CAB013645, HPA071089 Approved Supported Cytosol Tissue enriched 5 cerebral cortex: 134.7 parathyroid gland: 25.1 -GLI2 HPE9, THP1, THP2 ENSG00000074047 GLI family zinc finger 2 2 120735623-120992653 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008558, HPA074275 Approved Supported Nucleus
Nucleoli Tissue enhanced 0 ovary: 11.6 endometrium: 5.9 -CLASP1 KIAA0622, MAST1 ENSG00000074054 Cytoplasmic linker associated protein 1 2 121337776-121649587 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065219 Uncertain Expressed in all testis: 34.4 -MRPS34 MGC2616, MRP-S12 ENSG00000074071 Mitochondrial ribosomal protein S34 16 1771890-1773155 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042112 Supported Supported Mitochondria Expressed in all spleen: 22.6 -NOTCH3 CADASIL, CASIL ENSG00000074181 Notch 3 19 15159038-15200981 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005393, HPA044392 Approved Supported Nucleoplasm
Actin filaments
Cytosol Mixed skin: 93.5 -CLNS1A CLCI, ICln ENSG00000074201 Chloride channel, nucleotide-sensitive, 1A 11 77514936-77637805 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017840, HPA031707, HPA031708, HPA032045 Approved Supported Nucleus
Microtubules
Cytosol Expressed in all thyroid gland: 131.3 -PPP2R2C IMYPNO, MGC33570, PR52, PR55G ENSG00000074211 Protein phosphatase 2, regulatory subunit B, gamma 4 6320578-6563600 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042122, HPA042770, HPA060473 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 164.9 endometrium: 52.9 -TEAD2 ETF, TEF-4, TEF4 ENSG00000074219 TEA domain family member 2 19 49340595-49362457 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA066292, HPA069963 Supported Nucleoplasm Mixed endometrium: 58.7 -EED HEED, WAIT-1 ENSG00000074266 Embryonic ectoderm development 11 86244544-86278813 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012211, HPA060089, HPA061140 Supported Supported Nucleoplasm Expressed in all lymph node: 30.7 -CDHR2 FLJ20124, FLJ20383, PC-LKC, PCDH24, PCLKC ENSG00000074276 Cadherin-related family member 2 5 176542511-176595974 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012569, HPA017053 Supported Group enriched 12 duodenum: 284.1;small intestine: 265.8 colon: 23.1 -SNCB ENSG00000074317 Synuclein, beta 5 176620084-176630556 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002681, HPA035876 Supported Tissue enriched 70 cerebral cortex: 330.1 adrenal gland: 4.6 -TSG101 TSG10, VPS23 ENSG00000074319 Tumor susceptibility 101 11 18468336-18527232 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004283, HPA006161 Approved Supported Nucleoli
Plasma membrane
Cytosol Expressed in all parathyroid gland: 80.4 -NCBP3 C17orf85, ELG, HSA277841 ENSG00000074356 Nuclear cap binding subunit 3 17 3802165-3846251 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008959, HPA013195 Supported Approved Nuclear speckles Expressed in all testis: 16.4 -ATP2A3 SERCA3 ENSG00000074370 ATPase, Ca++ transporting, ubiquitous 17 3923870-3964464 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007180, CAB010882 Approved Expressed in all lymph node: 119.9 -CA12 HsT18816 ENSG00000074410 Carbonic anhydrase XII 15 63321378-63382161 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008773, CAB025181, CAB062549, CAB068179, HPA073203 Supported Approved Nucleus
Vesicles Tissue enhanced 0 kidney: 307.3;skin: 168.7 rectum: 105.5 -MGLL HU-K5, MGL ENSG00000074416 Monoglyceride lipase 3 127689062-127823250 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011348, HPA011993, HPA011994 Approved Supported Nucleoplasm Expressed in all adipose tissue: 188.0 -NTN4 ENSG00000074527 Netrin 4 12 95657807-95791152 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049832 Approved Tissue enhanced 0 spleen: 250.0 kidney: 117.8 -BCS1L BCS, BJS, h-BCS, Hs.6719 ENSG00000074582 BC1 (ubiquinol-cytochrome c reductase) synthesis-like 2 218658764-218663443 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037700, HPA037701 Supported Uncertain Vesicles Expressed in all fallopian tube: 30.9 -NUAK1 ARK5, KIAA0537, NuaK1 ENSG00000074590 NUAK family, SNF1-like kinase, 1 12 106063340-106140033 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027455, HPA057143 Approved Supported Nucleus
Nucleoli fibrillar center
Microtubules Tissue enhanced 0 cerebral cortex: 47.1;parathyroid gland: 41.6 skin: 21.0 -DPP8 DP8, DPRP1, FLJ14920, FLJ20283, MGC26191, MSTP141 ENSG00000074603 Dipeptidyl-peptidase 8 15 65442463-65517704 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008706 Approved Supported Cytosol Expressed in all testis: 47.9 -SLC24A1 CSNB1D, HsT17412, KIAA0702, NCKX, NCKX1, RODX ENSG00000074621 Solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 15 65611366-65660995 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039370 Supported Approved Microtubules Mixed fallopian tube: 8.7 -ZNF532 FLJ10697 ENSG00000074657 Zinc finger protein 532 18 58862600-58986480 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015322 Approved Approved Nucleoplasm
Golgi apparatus Mixed endometrium: 103.7 -SCARF1 KIAA0149, SREC ENSG00000074660 Scavenger receptor class F, member 1 17 1633858-1645747 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072936 Approved Tissue enhanced 0 spleen: 16.9 lung: 8.1 -LMAN1 ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60 ENSG00000074695 Lectin, mannose-binding, 1 18 59327823-59359962 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002320, CAB037163 Supported Uncertain Cytosol Expressed in all thyroid gland: 124.8 -HACD3 B-ind1, HSPC121, PTPLAD1 ENSG00000074696 3-hydroxyacyl-CoA dehydratase 3 15 65530418-65578352 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014837, HPA060347 Approved Validated Nuclear membrane
Endoplasmic reticulum
Mitochondria
Cytosol Expressed in all cerebral cortex: 139.3 -IPCEF1 KIAA0403, PIP3-E ENSG00000074706 Interaction protein for cytohesin exchange factors 1 6 154154496-154356792 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028708 Approved Tissue enhanced 0 thyroid gland: 65.7 cerebral cortex: 24.5 -ZZEF1 FLJ10821, KIAA0399, ZZZ4 ENSG00000074755 Zinc finger, ZZ-type with EF-hand domain 1 17 4004445-4143020 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031778, HPA031790 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all small intestine: 26.3 -NOX3 GP91-3 ENSG00000074771 NADPH oxidase 3 6 155395370-155455903 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA073837 Uncertain Vesicles Not detected adrenal gland: 0.1 -ENO1 ENO1L1, MBP-1, MPB1, PPH ENSG00000074800 Enolase 1, (alpha) 1 8861002-8879249 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018614, HPA068284, CAB069394 Supported Validated Nucleoplasm
Plasma membrane
Cytosol Expressed in all appendix: 789.1 -SLC12A1 NKCC2 ENSG00000074803 Solute carrier family 12 (sodium/potassium/chloride transporter), member 1 15 48191664-48304078 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014967, HPA018107 Supported Tissue enriched 456 kidney: 773.2 testis: 1.6 -MYDGF C19orf10, IL-25, IL-27, IL25, IL27, IL27w, R33729_1, SF20 ENSG00000074842 Myeloid-derived growth factor 19 4641374-4670370 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041872, HPA046744 Approved Expressed in all epididymis: 132.3 -ANO8 KIAA1623, TMEM16H ENSG00000074855 Anoctamin 8 19 17323223-17334829 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031787, HPA049206 Uncertain Uncertain Nucleoplasm
Nucleoli fibrillar center Tissue enhanced 0 cerebral cortex: 34.6 skin: 20.0 -TUBE1 dJ142L7.2, FLJ22589, TUBE ENSG00000074935 Tubulin, epsilon 1 6 112070777-112087529 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA032073, HPA032074 Approved Expressed in all testis: 54.9 -ARHGEF10L FLJ10521, KIAA1626 ENSG00000074964 Rho guanine nucleotide exchange factor (GEF) 10-like 1 17539835-17697874 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026426, HPA026440, HPA028115 Approved Approved Golgi apparatus
Vesicles
Cytosol Expressed in all thyroid gland: 29.6 -TXK BTKL, PSCTK5, PTK4, RLK, TKL ENSG00000074966 TXK tyrosine kinase 4 48066393-48134256 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062482 Approved Vesicles Tissue enhanced 0 lymph node: 18.1 spleen: 14.9 -WSCD2 KIAA0789 ENSG00000075035 WSC domain containing 2 12 108129471-108250537 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA013346, HPA048133 Approved Approved Nucleoplasm Tissue enhanced 0 seminal vesicle: 18.7;thyroid gland: 28.7 cerebral cortex: 14.2 -KCNQ2 BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, Kv7.2 ENSG00000075043 Potassium channel, voltage gated KQT-like subfamily Q, member 2 20 63400210-63472677 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016642, HPA057112 Approved Approved Endoplasmic reticulum Tissue enriched 7 cerebral cortex: 56.3 adrenal gland: 8.2 -TACR2 NK2R, NKNAR, SKR, TAC2R ENSG00000075073 Tachykinin receptor 2 10 69403903-69416867 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 smooth muscle: 66.9 esophagus: 23.2 -ACTR6 ARP6, FLJ13433 ENSG00000075089 ARP6 actin-related protein 6 homolog (yeast) 12 100199122-100241865 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038587, HPA038588 Uncertain Approved Plasma membrane
Cytosol Mixed testis: 16.2 -TIPIN FLJ20516 ENSG00000075131 TIMELESS interacting protein 15 66336206-66386746 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039704, HPA058799 Supported Supported Nucleus
Vesicles Tissue enhanced 0 testis: 36.7 parathyroid gland: 12.3 -SRI ENSG00000075142 Sorcin 7 88205118-88226993 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019004, HPA073666 Supported Supported Nucleoplasm
Cytosol Expressed in all colon: 572.6 -EIF4G3 eIF4GII ENSG00000075151 Eukaryotic translation initiation factor 4 gamma, 3 1 20806292-21176888 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025031, HPA025039, HPA025041 Supported Approved Cytosol Expressed in all testis: 169.5 -NUP37 FLJ22618, MGC5585 ENSG00000075188 Nucleoporin 37kDa 12 102073103-102120124 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056300, HPA073708 Supported Supported Nucleoplasm Expressed in all lymph node: 32.6 -SEMA3A coll-1, Hsema-I, SEMA1, SEMAD, SemD ENSG00000075213 Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 7 83955777-84492724 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029447, HPA052235 Approved Approved Nucleoplasm
Vesicles Mixed placenta: 14.4 -GTSE1 B99, GTSE-1 ENSG00000075218 G-2 and S-phase expressed 1 22 46296741-46330810 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029457, HPA060544 Uncertain Approved Plasma membrane
Centrosome Tissue enhanced 0 testis: 12.5 lymph node: 10.7 -SEMA3C SEMAE, SemE ENSG00000075223 Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 7 80742538-80922359 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042418 Uncertain Approved Golgi apparatus
Plasma membrane
Cytosol Mixed prostate: 98.7 -TTC38 FLJ20699 ENSG00000075234 Tetratricopeptide repeat domain 38 22 46267961-46294008 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029302 Approved Approved Cytosol Expressed in all small intestine: 90.1 -ACAT1 ACAT, THIL ENSG00000075239 Acetyl-CoA acetyltransferase 1 11 108121516-108147776 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004428, HPA007569 Supported Validated Mitochondria Expressed in all kidney: 530.1 -GRAMD4 DIP, KIAA0767 ENSG00000075240 GRAM domain containing 4 22 46576012-46679790 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all skin: 53.3 -CELSR1 ADGRC1, CDHF9, FMI2, HFMI2, ME2 ENSG00000075275 Cadherin, EGF LAG seven-pass G-type receptor 1 22 46360834-46537170 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052976, HPA060521, HPA067269 Uncertain Supported Plasma membrane Mixed fallopian tube: 15.4 -WNT8B ENSG00000075290 Wingless-type MMTV integration site family, member 8B 10 100463041-100483744 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036570 Uncertain Tissue enhanced 0 adrenal gland: 1.1;parathyroid gland: 1.5;testis: 1.6 kidney: 0.6 -ZNF638 MGC26130, NP220, ZFML, Zfp638 ENSG00000075292 Zinc finger protein 638 2 71276561-71435069 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036784, HPA057395 Supported Validated Nucleoplasm
Vesicles Expressed in all parathyroid gland: 57.8 -SLC25A40 MCFP ENSG00000075303 Solute carrier family 25, member 40 7 87833568-87876357 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055197 Uncertain Mixed prostate: 13.6 -TIMM21 C18orf55, HSPC154, TIM21 ENSG00000075336 Translocase of inner mitochondrial membrane 21 homolog (yeast) 18 74148511-74160530 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010587, HPA051543 Uncertain Approved Nucleoplasm Expressed in all heart muscle: 25.7 -ADD2 ADDB ENSG00000075340 Adducin 2 (beta) 2 70607618-70768225 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009796, HPA034509, HPA034510 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Group enriched 10 bone marrow: 40.3;cerebral cortex: 44.8 testis: 4.1 -FGF4 HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF ENSG00000075388 Fibroblast growth factor 4 11 69771016-69775403 Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011209 Uncertain Not detected testis: 0.4 -RASAL2 nGAP ENSG00000075391 RAS protein activator like 2 1 178094141-178484147 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018805, HPA020453 Approved Approved Plasma membrane
Focal adhesion sites Mixed esophagus: 19.5 -VPS9D1 ATP-BL, C16orf7 ENSG00000075399 VPS9 domain containing 1 16 89707134-89720986 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA007847, HPA023620 Uncertain Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 26.5 -ZNF37A KOX21, ZNF37 ENSG00000075407 Zinc finger protein 37A 10 38094336-38125544 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003172 Approved Approved Vesicles Expressed in all parathyroid gland: 18.1 -MARK3 CTAK1, KP78, PAR-1A ENSG00000075413 MAP/microtubule affinity-regulating kinase 3 14 103385392-103503831 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024652 Approved Approved Nuclear membrane Expressed in all bone marrow: 64.1 -SLC25A3 PHC ENSG00000075415 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 12 98593591-98606379 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045709 Supported Mitochondria Expressed in all parathyroid gland: 583.9 -FNDC3B DKFZp762K137, FAD104, FLJ23399, PRO4979, YVTM2421 ENSG00000075420 Fibronectin type III domain containing 3B 3 172039628-172401665 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007859 Uncertain Approved Endoplasmic reticulum Expressed in all placenta: 76.8 -FOSL2 FLJ23306, FRA2 ENSG00000075426 FOS-like antigen 2 2 28392448-28417312 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004817, CAB013460, HPA061417 Supported Validated Nucleus Expressed in all adrenal gland: 226.0 -CACNG5 ENSG00000075429 Calcium channel, voltage-dependent, gamma subunit 5 17 66835117-66885486 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA050115 Uncertain Tissue enhanced 0 cerebral cortex: 1.2 lymph node: 0.6 -CACNG4 MGC11138, MGC24983 ENSG00000075461 Calcium channel, voltage-dependent, gamma subunit 4 17 66964910-67033398 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA005803, HPA065370 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 48.7;prostate: 18.8 lung: 9.3 -FRYL AF4p12, DKFZp686E205, KIAA0826 ENSG00000075539 FRY-like 4 48497361-48780322 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031106, HPA031107 Supported Approved Microtubules
Cytokinetic bridge
Cytosol Expressed in all parathyroid gland: 50.3 -TMEM131 CC28, KIAA0257, PRO1048, RW1, YR-23 ENSG00000075568 Transmembrane protein 131 2 97756333-97995891 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017678, HPA017682 Approved Uncertain Vesicles
Intermediate filaments Expressed in all parathyroid gland: 46.7 -FSCN1 FLJ38511, p55, SNL ENSG00000075618 Fascin actin-bundling protein 1 7 5592823-5606655 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000121, HPA005723, CAB035991, HPA050654 Supported Supported Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 85.7 spleen: 55.9 -ACTB ENSG00000075624 Actin, beta 7 5527151-5563784 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002621, HPA041264, HPA041271 Supported Expressed in all smooth muscle: 7124.7 -MOCOS FLJ20733, HMCS, MOS ENSG00000075643 Molybdenum cofactor sulfurase 18 36187519-36272157 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039412, HPA047958 Uncertain Supported Mitochondria
Cytosol Mixed adrenal gland: 11.5 -PLD1 ENSG00000075651 Phospholipase D1, phosphatidylcholine-specific 3 171600405-171810950 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004527, HPA042396 Approved Approved Plasma membrane Tissue enhanced 0 gallbladder: 138.8 small intestine: 50.2 -ATP12A ATP1AL1 ENSG00000075673 ATPase, H+/K+ transporting, nongastric, alpha polypeptide 13 24680411-24712493 Enzymes, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039526 Approved Tissue enhanced 0 esophagus: 12.8;placenta: 8.1;tonsil: 14.6 skin: 7.1 -WDR62 C19orf14, DKFZP434J046, FLJ33298, MCPH2 ENSG00000075702 WD repeat domain 62 19 36054881-36105106 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043255, HPA043639, CAB046468 Approved Validated Cytosol Group enriched 7 skeletal muscle: 15.9;testis: 76.3 heart muscle: 6.7 -DLG1 dJ1061C18.1.1, DLGH1, hdlg, SAP-97, SAP97 ENSG00000075711 Discs, large homolog 1 (Drosophila) 3 197042560-197299300 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016307, HPA069593 Supported Uncertain Vesicles
Plasma membrane Expressed in all thyroid gland: 94.5 -RAB7A RAB7 ENSG00000075785 RAB7A, member RAS oncogene family 3 128726122-128814796 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006964, CAB037131 Supported Supported Lysosomes Expressed in all cerebral cortex: 271.1 -BCAP29 BAP29, DKFZp686M2086 ENSG00000075790 B-cell receptor-associated protein 29 7 107579977-107629170 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029215, HPA049694 Supported Approved Cytosol Expressed in all thyroid gland: 185.4 -SEC31B DKFZP434M183, SEC31B-1, SEC31L2 ENSG00000075826 SEC31 homolog B, COPII coat complex component 10 100486642-100519864 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035882, HPA040819, HPA060052 Uncertain Approved Nucleus
Nucleoli
Vesicles
Cytosol Mixed testis: 3.2 -SART3 KIAA0156, p110, RP11-13G14, TIP110 ENSG00000075856 Squamous cell carcinoma antigen recognized by T cells 3 12 108522580-108561400 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044322 Approved Expressed in all parathyroid gland: 33.3 -ARHGAP15 BM046 ENSG00000075884 Rho GTPase activating protein 15 2 143091362-143768352 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032125 Uncertain Uncertain Nucleoplasm
Golgi apparatus
Vesicles Tissue enhanced 0 lymph node: 66.2 spleen: 60.5 -TUBA3D H2-ALPHA ENSG00000075886 Tubulin, alpha 3d 2 131476093-131482934 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB004972, HPA039247, HPA043684, HPA063394 Uncertain Supported Microtubules Tissue enriched 30 testis: 249.9 epididymis: 8.3 -PAX2 ENSG00000075891 Paired box 2 10 100735603-100829941 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB013024, HPA047704, HPA070751 Supported Supported Nucleoli
Golgi apparatus Group enriched 5 epididymis: 36.6;fallopian tube: 18.8;kidney: 25.2;seminal vesicle: 19.8 cervix: 4.9 -EXOSC7 EAP1, hRrp42p, KIAA0116, p8, RRP42, Rrp42p ENSG00000075914 Exosome component 7 3 44975241-45036066 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036182, HPA057980 Approved Supported Nuclear speckles Expressed in all adrenal gland: 45.1 -KIFAP3 FLA3, KAP-1, KAP3, SMAP ENSG00000075945 Kinesin-associated protein 3 1 169921326-170085208 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023738, HPA023742 Supported Expressed in all cerebral cortex: 106.4 -MKRN2 HSPC070, RNF62 ENSG00000075975 Makorin ring finger protein 2 3 12557014-12583713 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037559, HPA037560 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 99.8 -MCM6 Mis5 ENSG00000076003 Minichromosome maintenance complex component 6 2 135839626-135876426 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004818, CAB009577 Supported Validated Nucleoplasm Mixed lymph node: 41.2 -REXO2 CGI-114, DKFZP566E144, SFN ENSG00000076043 RNA exonuclease 2 11 114439386-114450279 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038450, HPA038451 Supported Supported Nucleoli
Focal adhesion sites
Mitochondria Expressed in all parathyroid gland: 254.4 -RBM7 ENSG00000076053 RNA binding motif protein 7 11 114400030-114414203 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013993, HPA048003 Supported Validated Nucleoplasm Expressed in all bone marrow: 40.9 -RBMS2 SCR3 ENSG00000076067 RNA binding motif, single stranded interacting protein 2 12 56521929-56596196 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039225, HPA058784 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all lung: 35.8 -BAZ2A KIAA0314, TIP5, WALp3 ENSG00000076108 Bromodomain adjacent to zinc finger domain, 2A 12 56595596-56636816 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005782, HPA063806 Validated Nuclear speckles Expressed in all testis: 82.6 -PTPN23 DKFZP564F0923, HD-PTP, KIAA1471 ENSG00000076201 Protein tyrosine phosphatase, non-receptor type 23 3 47381011-47413441 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016845 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 56.0 -MLH1 COCA2, FCC2, HNPCC, HNPCC2 ENSG00000076242 MutL homolog 1 3 36993332-37050918 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013294, HPA052707, HPA060714, CAB070868 Supported Validated Nucleoplasm Expressed in all testis: 59.7 -UNG DGU, HIGM4, UDG, UNG1, UNG2 ENSG00000076248 Uracil DNA glycosylase 12 109097574-109110992 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011605 Uncertain Approved Cytosol Expressed in all adrenal gland: 56.4 -FMO4 FMO2 ENSG00000076258 Flavin containing monooxygenase 4 1 171314208-171342084 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049100 Uncertain Tissue enhanced 0 kidney: 47.7;liver: 30.1 parathyroid gland: 10.7 -KLHL20 KHLHX, KLEIP ENSG00000076321 Kelch-like family member 20 1 173714941-173786702 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025034, HPA053704 Approved Supported Golgi apparatus
Cytosol Expressed in all testis: 29.2 -RGS11 ENSG00000076344 Regulator of G-protein signaling 11 16 268301-275980 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041692, HPA043039 Uncertain Tissue enhanced 0 cerebral cortex: 20.4 adipose tissue: 8.1 -SLC46A1 HCP1, MGC9564, PCFT ENSG00000076351 Solute carrier family 46 (folate transporter), member 1 17 28394756-28407197 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011614 Approved Supported Plasma membrane
Cytosol Expressed in all duodenum: 97.7 -PLXNA2 FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2 ENSG00000076356 Plexin A2 1 208022242-208244320 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009763 Approved Mixed ovary: 16.9 -SPAG5 DEEPEST, hMAP126, MAP126 ENSG00000076382 Sperm associated antigen 5 17 28577565-28599279 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022008, HPA022479 Approved Tissue enhanced 0 testis: 119.5 kidney: 25.0 -ANKRD13A ANKRD13, NY-REN-25 ENSG00000076513 Ankyrin repeat domain 13A 12 109999186-110039763 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039488, HPA043218 Supported Supported Plasma membrane Expressed in all testis: 112.0 -TPD52 D52, hD52, N8L ENSG00000076554 Tumor protein D52 8 80034745-80231232 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028427, HPA062167 Supported Approved Golgi apparatus
Cytosol Expressed in all prostate: 173.6 -ACACB ACC2, ACCB, HACC275 ENSG00000076555 Acetyl-CoA carboxylase beta 12 109116595-109268226 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006554 Supported Tissue enriched 6 adipose tissue: 194.0 parathyroid gland: 30.2 -TRAF4 CART1, MLN62, RNF83 ENSG00000076604 TNF receptor-associated factor 4 17 28743984-28750958 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052377 Supported Mixed duodenum: 48.5 -PAG1 CBP, PAG ENSG00000076641 Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 8 80967810-81112068 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001632, HPA066527 Uncertain Supported Vesicles
Plasma membrane Mixed placenta: 22.8 -GPATCH1 ECGP, FLJ10206, FLJ38686, GPATC1 ENSG00000076650 G patch domain containing 1 19 33080880-33130542 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043430, HPA043604 Approved Uncertain Nucleoplasm
Plasma membrane
Cell Junctions Mixed parathyroid gland: 8.5 -ICAM3 CD50, CDW50, ICAM-R ENSG00000076662 Intercellular adhesion molecule 3 19 10333776-10339823 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002498, HPA049820 Supported Approved Nucleus
Nuclear membrane
Mitochondria Expressed in all bone marrow: 112.2 -NT5C2 cN-II, GMP, NT5B, PNT5, SPG65 ENSG00000076685 5'-nucleotidase, cytosolic II 10 103088017-103193306 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003751 Approved Expressed in all thyroid gland: 118.9 -MCAM CD146, MUC18 ENSG00000076706 Melanoma cell adhesion molecule 11 119308529-119321521 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002147, HPA008848 Supported Validated Plasma membrane Mixed adipose tissue: 365.9 -GPC4 K-glypican ENSG00000076716 Glypican 4 X 133300103-133415490 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030836 Approved Approved Vesicles Mixed placenta: 41.4 -MBNL3 CHCR, FLJ11316, MBLX39, MBXL ENSG00000076770 Muscleblind-like splicing regulator 3 X 132369317-132489968 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001584 Supported Approved Golgi apparatus
Vesicles Group enriched 5 placenta: 240.2;testis: 81.1 liver: 30.5 -CAMSAP3 KIAA1543, Nezha, PPP1R80 ENSG00000076826 Calmodulin regulated spectrin-associated protein family, member 3 19 7595902-7618304 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043830, HPA062149 Approved Approved Nucleoplasm
Centrosome Tissue enhanced 0 skin: 22.1 duodenum: 15.6 -RAP1GAP KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII ENSG00000076864 RAP1 GTPase activating protein 1 21596215-21669363 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001922 Supported Supported Tissue enhanced 0 cerebral cortex: 122.5;thyroid gland: 232.1 adrenal gland: 93.7 -XAB2 HCNP, HCRN, NTC90, SYF1 ENSG00000076924 XPA binding protein 2 19 7619525-7629565 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048751 Approved Nucleus
Vesicles Expressed in all testis: 39.3 -ARHGEF1 LBCL2, P115-RHOGEF, SUB1.5 ENSG00000076928 Rho guanine nucleotide exchange factor (GEF) 1 19 41883161-41930150 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009502, HPA012924, HPA060784 Supported Validated Plasma membrane
Cytosol Expressed in all lymph node: 147.0 -STXBP2 Hunc18b, UNC18B ENSG00000076944 Syntaxin binding protein 2 19 7636881-7647873 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015564, HPA063868 Approved Validated Cytosol Mixed bone marrow: 125.6 -MAP2K7 Jnkk2, MKK7, PRKMK7 ENSG00000076984 Mitogen-activated protein kinase kinase 7 19 7903843-7914478 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001633, CAB004262, HPA064711 Supported Approved Golgi apparatus
Plasma membrane
Cytosol Expressed in all spleen: 19.5 -NMRK2 ITGB1BP3, MIBP, NRK2 ENSG00000077009 Nicotinamide riboside kinase 2 19 3933103-3942416 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049909, HPA054792, HPA072450 Approved Approved Nucleoplasm
Vesicles Group enriched 50 heart muscle: 396.7;skeletal muscle: 218.5 esophagus: 6.1 -DGKD DGKdelta, KIAA0145 ENSG00000077044 Diacylglycerol kinase, delta 130kDa 2 233354507-233472104 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027530, HPA049101 Approved Supported Cytosol Mixed testis: 20.8 -CTTNBP2 C7orf8, CORTBP2, KIAA1758, Orf4 ENSG00000077063 Cortactin binding protein 2 7 117710651-117874139 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009151, HPA044654 Approved Approved Midbody ring
Cytosol Mixed parathyroid gland: 18.8 -ACTL6B ACTL6, BAF53B ENSG00000077080 Actin-like 6B 7 100643097-100656461 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045126 Uncertain Approved Nucleoli Tissue enriched 19 cerebral cortex: 45.7 adrenal gland: 2.4 -RARB HAP, NR1B2, RRB2 ENSG00000077092 Retinoic acid receptor, beta 3 25174332-25597932 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB002617, HPA004174 Supported Validated Nucleoplasm Mixed placenta: 20.5 -TOP2B ENSG00000077097 Topoisomerase (DNA) II beta 3 25597905-25664907 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004601, HPA024120, HPA050441 Supported Validated Nucleus Expressed in all parathyroid gland: 105.5 -TM9SF3 SMBP ENSG00000077147 Transmembrane 9 superfamily member 3 10 96518109-96587452 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039609 Approved Approved Golgi apparatus
Vesicles Expressed in all stomach: 182.0 -NFKB2 LYT-10, NF-kB2, p105, p52 ENSG00000077150 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 10 102394110-102402529 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008422, CAB022098, HPA023900 Supported Approved Nucleoplasm
Cytosol Expressed in all appendix: 72.8 -UBE2T FANCT, HSPC150 ENSG00000077152 Ubiquitin-conjugating enzyme E2T 1 202331657-202341980 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002831 Approved Nucleus
Nucleoli Mixed testis: 35.8 -PPP1R12B MGC131980, MGC87886, MYPT2, PP1bp55 ENSG00000077157 Protein phosphatase 1, regulatory subunit 12B 1 202348699-202592706 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024171, HPA024640 Supported Supported Plasma membrane
Actin filaments Expressed in all endometrium: 363.9 -DNAJC10 ERdj5, PDIA19 ENSG00000077232 DnaJ (Hsp40) homolog, subfamily C, member 10 2 182716041-182794464 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031111 Approved Expressed in all epididymis: 152.2 -GTF3C1 TFIIIC220 ENSG00000077235 General transcription factor IIIC, polypeptide 1, alpha 220kDa 16 27459555-27549913 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051617 Approved Supported Nucleus
Nucleoli Expressed in all thyroid gland: 49.6 -IL4R CD124 ENSG00000077238 Interleukin 4 receptor 16 27313668-27364778 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004451, HPA050124 Supported Approved Cytosol Expressed in all lymph node: 139.5 -USP33 KIAA1097, VDU1 ENSG00000077254 Ubiquitin specific peptidase 33 1 77695987-77759852 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005719 Uncertain Supported Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 55.0 -PAK3 bPAK, hPAK3, MRX30, MRX47 ENSG00000077264 P21 protein (Cdc42/Rac)-activated kinase 3 X 110944285-111227361 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044791, HPA060219 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 34.4 thyroid gland: 10.3 -CAPN6 CalpM, CANPX, CAPNX ENSG00000077274 Calpain 6 X 111245103-111270523 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040383 Uncertain Cytosol Tissue enhanced 0 epididymis: 251.6;placenta: 116.3;seminal vesicle: 99.3 endometrium: 36.9 -DCX DBCN, DC, LISX, SCLH, XLIS ENSG00000077279 Doublecortin X 111293780-111412375 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036121, HPA059243 Supported Supported Cytosol Tissue enhanced 0 cerebral cortex: 11.3 endometrium: 2.6 -SNRPA Mud1, U1-A, U1A ENSG00000077312 Small nuclear ribonucleoprotein polypeptide A 19 40750637-40765389 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004652, HPA046440, HPA054834 Supported Validated Nucleoplasm Expressed in all lymph node: 61.5 -SPAG6 CT141, pf16, Repro-SA-1 ENSG00000077327 Sperm associated antigen 6 10 22345445-22454224 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038440 Supported Group enriched 12 fallopian tube: 76.6;testis: 171.7 lung: 10.7 -EXOSC5 hRrp46p, MGC12901, p12B, RRP41B, RRP46, Rrp46p ENSG00000077348 Exosome component 5 19 41386374-41397479 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053150, HPA055677 Approved Validated Nucleus
Nucleoli Expressed in all skin: 22.1 -DYNC1I2 DNCI2 ENSG00000077380 Dynein, cytoplasmic 1, intermediate chain 2 2 171687409-171748420 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033836, HPA040619, HPA053987 Supported Supported Nucleoli
Endoplasmic reticulum
Microtubules
Cytosol Expressed in all cerebral cortex: 147.0 -APBB1IP INAG1, RIAM ENSG00000077420 Amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 10 26438203-26567803 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017009, HPA063903 Supported Validated Plasma membrane
Cytosol Mixed appendix: 63.1 -LRCH4 LRN, LRRN1 ENSG00000077454 Leucine-rich repeats and calponin homology (CH) domain containing 4 7 100574011-100586153 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037667, HPA037668 Supported Approved Nucleoplasm
Focal adhesion sites
Cytosol Expressed in all spleen: 107.7 -FAM76B MGC33371 ENSG00000077458 Family with sequence similarity 76, member B 11 95768942-95790409 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036608 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all testis: 32.9 -SIRT6 ENSG00000077463 Sirtuin 6 19 4174109-4182604 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049729, HPA071776 Supported Supported Nucleoplasm Expressed in all colon: 13.5 -TYR OCA1, OCA1A, OCAIA ENSG00000077498 Tyrosinase 11 89177452-89295759 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000079, HPA043241, HPA050889 Supported Validated Vesicles Tissue enriched 33 skin: 29.9 breast: 0.9 -POLD3 KIAA0039, P66, P68, PPP1R128 ENSG00000077514 Polymerase (DNA-directed), delta 3, accessory subunit 11 74493851-74669117 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058846 Supported Supported Nucleus Expressed in all kidney: 45.2 -ACTN2 ENSG00000077522 Actinin, alpha 2 1 236686454-236764631 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006035, HPA008315 Supported Group enriched 27 heart muscle: 461.7;skeletal muscle: 758.8 esophagus: 22.5 -CAPZB ENSG00000077549 Capping protein (actin filament) muscle Z-line, beta 1 19338776-19485539 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031531, HPA056066 Approved Validated Nucleoplasm
Vesicles
Cytosol Expressed in all smooth muscle: 484.4 -GPR137B TM7SF1 ENSG00000077585 G protein-coupled receptor 137B 1 236142505-236221865 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026422 Approved Mixed kidney: 70.2 -NAALAD2 GPCIII, NAADALASE2, NAALADASE2 ENSG00000077616 N-acetylated alpha-linked acidic dipeptidase 2 11 90131515-90192894 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060820, HPA065419 Approved Approved Nucleus Tissue enhanced 0 testis: 27.2 endometrium: 13.7 -JADE1 JADE-1, PHF17 ENSG00000077684 Jade family PHD finger 1 4 128809623-128875224 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020016 Approved Approved Mitochondria Expressed in all thyroid gland: 52.7 -SLC25A43 ENSG00000077713 Solute carrier family 25, member 43 X 119399060-119454478 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035188 Uncertain Approved Nucleus Mixed esophagus: 20.6 -UBE2A HHR6A, RAD6A, UBC2 ENSG00000077721 Ubiquitin-conjugating enzyme E2A X 119574467-119591083 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003875, HPA051765, HPA065898 Supported Nucleoplasm
Vesicles
Plasma membrane
Cytosol Expressed in all placenta: 75.9 -FGFR1 BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM ENSG00000077782 Fibroblast growth factor receptor 1 8 38411138-38468834 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033614, HPA056402, HPA076274 Approved Approved Nucleoli Expressed in all gallbladder: 109.6 -FKBP6 FKBP36, PPIase ENSG00000077800 FK506 binding protein 6, 36kDa 7 73328164-73358637 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061109 Supported Tissue enriched 269 testis: 82.6 fallopian tube: 0.3 -SMC1B bK268H5, SMC1L2 ENSG00000077935 Structural maintenance of chromosomes 1B 22 45344063-45413619 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA001500 Supported Supported Nucleoplasm
Cytosol Tissue enriched 115 testis: 57.1 parathyroid gland: 0.4 -FBLN1 FBLN ENSG00000077942 Fibulin 1 22 45502238-45601135 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001612, HPA001613, CAB004393, CAB068187 Supported Approved Endoplasmic reticulum Expressed in all cervix: 1317.9 -ITGA8 ENSG00000077943 Integrin, alpha 8 10 15513949-15720125 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA003432 Approved Tissue enhanced 0 prostate: 55.8 seminal vesicle: 40.0 -CST7 ENSG00000077984 Cystatin F (leukocystatin) 20 24949230-24959928 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040442 Supported Tissue enriched 9 bone marrow: 644.5 spleen: 75.4 -MAP2 MAP2A, MAP2B, MAP2C ENSG00000078018 Microtubule-associated protein 2 2 209424058-209734118 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001984, HPA008273, HPA012828 Supported Supported Supported Nucleoli
Cytosol Tissue enriched 11 cerebral cortex: 297.4 thyroid gland: 27.8 -PIAS2 miz, PIASX-ALPHA, PIASX-BETA, ZMIZ4 ENSG00000078043 Protein inhibitor of activated STAT, 2 18 46803224-46920160 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068792 Supported Approved Nucleoplasm Group enriched 5 parathyroid gland: 28.3;testis: 118.8 thyroid gland: 13.8 -AMPH ENSG00000078053 Amphiphysin 7 38383704-38631567 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008559, HPA019828, HPA019829 Supported Supported Plasma membrane
Cytosol Tissue enriched 9 cerebral cortex: 84.0 cervix: 8.9 -ARAF ARAF1 ENSG00000078061 A-Raf proto-oncogene, serine/threonine kinase X 47561100-47571920 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046188, HPA066326 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all parathyroid gland: 84.7 -MCCC1 MCCA ENSG00000078070 Methylcrotonoyl-CoA carboxylase 1 (alpha) 3 183015218-183116075 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008310 Approved Validated Mitochondria Expressed in all kidney: 60.7 -LAMP3 CD208, DC-LAMP, DCLAMP, LAMP, TSC403 ENSG00000078081 Lysosomal-associated membrane protein 3 3 183122213-183163839 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025133, HPA051467 Supported Supported Nucleus
Vesicles Tissue enriched 7 lung: 320.1 appendix: 46.2 -FAP DPPIV ENSG00000078098 Fibroblast activation protein, alpha 2 162170684-162245151 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059739 Approved Tissue enhanced 0 endometrium: 50.4 smooth muscle: 37.9 -NEBL ENSG00000078114 Nebulette 10 20779973-21174187 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013994, HPA013995 Approved Tissue enhanced 0 heart muscle: 198.5;thyroid gland: 124.9 cerebral cortex: 61.5 -ACER3 APHC, FLJ11238, PHCA ENSG00000078124 Alkaline ceramidase 3 11 76860867-77026797 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 14.3 -UBE2K HIP2, HYPG, UBC1 ENSG00000078140 Ubiquitin-conjugating enzyme E2K 4 39698044-39782792 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028869, CAB033212, CAB033515 Supported Approved Actin filaments
Cytosol Expressed in all cerebral cortex: 64.9 -PIK3C3 Vps34 ENSG00000078142 Phosphatidylinositol 3-kinase, catalytic subunit type 3 18 41955206-42087830 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040718 Approved Expressed in all testis: 33.0 -N4BP2 B3BP ENSG00000078177 NEDD4 binding protein 2 4 40056826-40158252 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036770, HPA042607 Approved Approved Nucleoplasm
Plasma membrane
Centrosome Mixed thyroid gland: 5.5 -TIGAR C12orf5 ENSG00000078237 TP53 induced glycolysis regulatory phosphatase 12 4307763-4354593 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034010, HPA040354, HPA044111 Approved Supported Cytosol Mixed appendix: 9.9 -TULP3 TUBL3 ENSG00000078246 Tubby like protein 3 12 2877223-2941140 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015285, HPA018496 Uncertain Supported Nucleus
Nucleoli
Plasma membrane Expressed in all ovary: 46.4 -SYNJ2 INPP5H ENSG00000078269 Synaptojanin 2 6 157981887-158099176 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031575 Approved Approved Microtubules
Cytosol Expressed in all cerebral cortex: 35.6 -ADCY2 AC2, HBAC2, KIAA1060 ENSG00000078295 Adenylate cyclase 2 (brain) 5 7396208-7830081 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB031482, HPA038015, HPA038483 Approved Tissue enhanced 0 cerebral cortex: 71.8;skeletal muscle: 35.8 prostate: 13.6 -PPP2R5C B56G, PR61G ENSG00000078304 Protein phosphatase 2, regulatory subunit B', gamma 14 101761798-101927989 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027553 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all lymph node: 160.0 -RBFOX1 A2BP1, FOX-1, HRNBP1 ENSG00000078328 RNA binding protein, fox-1 homolog (C. elegans) 1 16 6019094-7713338 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA040809 Supported Approved Nucleus
Golgi apparatus
Cytosol Tissue enhanced 0 cerebral cortex: 110.9;skeletal muscle: 32.9 heart muscle: 14.8 -GNB1 ENSG00000078369 Guanine nucleotide binding protein (G protein), beta polypeptide 1 1 1785285-1891117 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040736 Supported Uncertain Golgi apparatus
Plasma membrane Expressed in all cerebral cortex: 448.5 -HOXA9 HOX1, HOX1G ENSG00000078399 Homeobox A9 7 27162435-27175180 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA061982 Uncertain Supported Nucleus Mixed kidney: 12.5 -EDN1 ET1 ENSG00000078401 Endothelin 1 6 12290363-12297194 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA031976, CAB032500, CAB037291 Approved Approved Nucleus
Nucleoli
Golgi apparatus Mixed lung: 43.6 -MLLT10 AF10 ENSG00000078403 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 10 21524675-21743630 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005747 Supported Supported Nucleoplasm Expressed in all testis: 176.8 -ZCWPW1 DKFZp434N0510, FLJ10057, ZCW1 ENSG00000078487 Zinc finger, CW type with PWWP domain 1 7 100400826-100428992 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020061, HPA020911 Uncertain Approved Golgi apparatus Tissue enriched 8 testis: 70.9 thyroid gland: 8.6 -ADCYAP1R1 PAC1, PAC1R, PACAPR ENSG00000078549 Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7 31052461-31111479 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049877 Approved Uncertain Vesicles Tissue enhanced 0 cerebral cortex: 137.5;fallopian tube: 46.5 cervix: 20.6 -FGF20 ENSG00000078579 Fibroblast growth factor 20 8 16992169-17002181 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed spleen: 1.5 -P2RY10 P2Y10 ENSG00000078589 Purinergic receptor P2Y, G-protein coupled, 10 X 78945332-78961954 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036757, HPA065766 Approved Tissue enhanced 0 lymph node: 33.5;spleen: 23.0;tonsil: 24.9 appendix: 20.1 -ITM2A BRICD2A, E25A ENSG00000078596 Integral membrane protein 2A X 79360384-79367667 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002918 Uncertain Nucleoplasm Expressed in all ovary: 219.0 -NRD1 hNRD1, hNRD2 ENSG00000078618 Nardilysin (N-arginine dibasic convertase) 1 51789191-51878937 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053661 Approved Nucleoplasm Expressed in all testis: 167.1 -VDAC3 HD-VDAC3 ENSG00000078668 Voltage-dependent anion channel 3 8 42391624-42405897 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026864 Uncertain Supported Mitochondria Expressed in all skeletal muscle: 327.2 -PCM1 PTC4 ENSG00000078674 Pericentriolar material 1 8 17922840-18029944 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023370, HPA023374, CAB058695 Supported Validated Nuclear membrane
Centrosome
Cytosol Expressed in all testis: 275.8 -TNRC6C FLJ20015, KIAA1582 ENSG00000078687 Trinucleotide repeat containing 6C 17 78004168-78108835 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022007, HPA062051 Uncertain Approved Nucleus Mixed cerebral cortex: 17.8 -CBFA2T2 MTGR1, ZMYND3 ENSG00000078699 Core-binding factor, runt domain, alpha subunit 2; translocated to, 2 20 33490075-33650036 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060523, HPA072433 Supported Approved Nuclear speckles Expressed in all prostate: 23.0 -BRINP1 DBC1, DBCCR1, FAM5A ENSG00000078725 Bone morphogenetic protein/retinoic acid inducible neural-specific 1 9 119153458-119369467 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038828 Approved Approved Microtubules Tissue enriched 8 cerebral cortex: 59.7 seminal vesicle: 7.1 -ITCH AIP4 ENSG00000078747 Itchy E3 ubiquitin protein ligase 20 34363235-34511393 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021126, HPA049032 Supported Supported Nucleoplasm Expressed in all testis: 58.8 -PKD2L2 TRPP5 ENSG00000078795 Polycystic kidney disease 2-like 2 5 137887968-137942747 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041903, HPA043634 Approved Approved Plasma membrane
Cytosol Tissue enriched 11 testis: 15.6 thyroid gland: 1.4 -TP53INP2 C20orf110, dJ1181N3.1, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, PINH ENSG00000078804 Tumor protein p53 inducible nuclear protein 2 20 34704290-34713439 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 87.1 -SDF4 Cab45 ENSG00000078808 Stromal cell derived factor 4 1 1216908-1232031 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011249, CAB015227 Supported Validated Golgi apparatus Expressed in all small intestine: 131.3 -MYH7B dJ756N5.1, KIAA1512, MHC14, MYH14 ENSG00000078814 Myosin, heavy chain 7B, cardiac muscle, beta 20 34975403-35002437 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 11 heart muscle: 41.9;skeletal muscle: 55.9;testis: 11.8 cerebral cortex: 3.3 -BPIFB2 BPIL1, C20orf184, dJ726C3.2, LPLUNC2 ENSG00000078898 BPI fold containing family B, member 2 20 33007600-33023709 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049491, HPA060121 Supported Approved Vesicles Group enriched 23 esophagus: 99.0;salivary gland: 91.0 cervix: 4.0 -TP73 P73 ENSG00000078900 Tumor protein p73 1 3652520-3736201 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002514, CAB003022, HPA027314, HPA044516 Supported Supported Nucleoplasm
Golgi apparatus Group enriched 5 fallopian tube: 11.0;skin: 8.1 prostate: 1.8 -TOLLIP IL-1RAcPIP ENSG00000078902 Toll interacting protein 11 1274371-1309654 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038621, HPA038622 Supported Approved Plasma membrane
Cytosol Expressed in all cerebral cortex: 132.7 -UBE2D4 HBUCE1 ENSG00000078967 Ubiquitin-conjugating enzyme E2D 4 (putative) 7 43926438-43956136 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003920 Approved Approved Plasma membrane
Cytosol Expressed in all cerebral cortex: 12.6 -CLUL1 ENSG00000079101 Clusterin-like 1 (retinal) 18 596988-650334 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB025264, HPA044243 Uncertain Approved Vesicles Mixed prostate: 14.6 -RUNX1T1 AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2 ENSG00000079102 Runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 8 91954967-92103286 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049852, HPA070951 Approved Approved Nucleoplasm Mixed cervix: 12.9 -CDH17 cadherin, HPT-1 ENSG00000079112 Cadherin 17, LI cadherin (liver-intestine) 8 94127171-94217303 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023614, HPA023616, CAB025143, HPA026556 Supported Supported Cell Junctions Group enriched 7 colon: 261.7;duodenum: 323.0;rectum: 272.5;small intestine: 300.5 appendix: 39.2 -THOC1 HPR1, P84 ENSG00000079134 THO complex 1 18 214520-268050 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019096, HPA019687 Supported Validated Nuclear speckles Mixed testis: 29.2 -FKBP7 FKBP23 ENSG00000079150 FK506 binding protein 7 2 178463664-178478600 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008707 Approved Supported Supported Endoplasmic reticulum Tissue enhanced 0 ovary: 60.4 endometrium: 44.1 -OSBPL6 ORP6 ENSG00000079156 Oxysterol binding protein-like 6 2 178194481-178402891 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032131 Supported Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 15.5 skin: 9.2 -SLC1A3 EA6, EAAT1, GLAST ENSG00000079215 Solute carrier family 1 (glial high affinity glutamate transporter), member 3 5 36606355-36688334 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002573, HPA037467, HPA037468 Supported Approved Nucleoli
Mitochondria Tissue enriched 16 cerebral cortex: 519.6 adipose tissue: 31.7 -XRCC5 KARP-1, KU80, Ku86, KUB2 ENSG00000079246 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 2 216107464-216206303 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004468, HPA025813, HPA064685 Supported Validated Nucleoplasm Expressed in all thyroid gland: 212.5 -LXN ENSG00000079257 Latexin 3 158645822-158672693 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014179, CAB025128 Approved Validated Nucleoplasm
Cytosol Expressed in all gallbladder: 61.1 -SP140 LYSP100-A, LYSP100-B ENSG00000079263 SP140 nuclear body protein 2 230203110-230313215 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006162, HPA067493 Supported Approved Nucleoli fibrillar center
Mitochondria Group enriched 6 appendix: 34.0;lymph node: 65.2;spleen: 38.9;tonsil: 52.9 urinary bladder: 7.9 -MKNK1 MNK1 ENSG00000079277 MAP kinase interacting serine/threonine kinase 1 1 46557408-46616843 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071293 Supported Nucleoplasm Expressed in all appendix: 45.4 -TNS1 DKFZp586K0617, MXRA6, PPP1R155, TNS ENSG00000079308 Tensin 1 2 217799789-218002995 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018774, HPA036089, HPA036090 Approved Validated Focal adhesion sites Expressed in all seminal vesicle: 316.2 -REXO1 EloA-BP1, KIAA1138, TCEB3BP1 ENSG00000079313 REX1, RNA exonuclease 1 homolog 19 1815246-1848463 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042155, HPA042552 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 35.5 -SAR1A SAR1, Sara, SARA1 ENSG00000079332 Secretion associated, Ras related GTPase 1A 10 70147289-70170523 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006923, CAB022545, HPA048368 Supported Supported Endoplasmic reticulum Expressed in all placenta: 115.5 -CDC14A cdc14, Cdc14A1, Cdc14A2 ENSG00000079335 Cell division cycle 14A 1 100345025-100520277 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA023783 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Tissue enhanced 0 testis: 56.0 fallopian tube: 19.6 -RAPGEF3 bcm910, cAMP-GEFI, EPAC ENSG00000079337 Rap guanine nucleotide exchange factor (GEF) 3 12 47734367-47771040 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004386, HPA040365, HPA043518 Approved Approved Cytosol Mixed thyroid gland: 42.9 -CEACAM1 BGP, BGP1, CD66a ENSG00000079385 Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 19 42507304-42561234 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002146, HPA011041 Supported Tissue enhanced 0 colon: 205.9;rectum: 132.8 esophagus: 46.7 -SENP1 ENSG00000079387 SUMO1/sentrin specific peptidase 1 12 48042898-48106308 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011765, HPA046491 Uncertain Validated Nucleus
Focal adhesion sites Tissue enriched 8 testis: 109.5 lymph node: 13.4 -DUSP13 BEDP, DUSP13A, DUSP13B, FLJ32450, TMDP ENSG00000079393 Dual specificity phosphatase 13 10 75094432-75109221 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 7 skeletal muscle: 84.9;testis: 47.5 heart muscle: 9.3 -CIC KIAA0306 ENSG00000079432 Capicua transcriptional repressor 19 42268537-42295797 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026388, HPA044341, HPA064725 Approved Supported Nucleoplasm
Vesicles Expressed in all testis: 55.0 -LIPE HSL ENSG00000079435 Lipase, hormone-sensitive 19 42401507-42427426 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006567, CAB017700 Supported Supported Cytosol Tissue enriched 20 adipose tissue: 868.9 testis: 44.2 -FDFT1 ENSG00000079459 Farnesyl-diphosphate farnesyltransferase 1 8 11795573-11839309 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008874 Approved Supported Endoplasmic reticulum Expressed in all testis: 204.4 -PAFAH1B3 ENSG00000079462 Platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 19 42297033-42303546 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035639 Uncertain Approved Intermediate filaments Expressed in all cerebral cortex: 36.8 -OPHN1 ARHGAP41, MRX60, OPN1 ENSG00000079482 Oligophrenin 1 X 68042344-68433913 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002919 Approved Approved Nucleus
Plasma membrane Mixed cerebral cortex: 20.3 -AFM ALB2, ALBA ENSG00000079557 Afamin 4 73481683-73504001 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017006 Supported Tissue enriched 6 liver: 467.3 kidney: 80.2 -KIF22 Kid, KNSL4, OBP-1, OBP-2 ENSG00000079616 Kinesin family member 22 16 29790719-29805385 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041076, HPA048213 Approved Approved Nuclear speckles Expressed in all bone marrow: 54.0 -SCGN CALBL, DJ501N12.8, SECRET, SEGN ENSG00000079689 Secretagogin, EF-hand calcium binding protein 6 25652201-25701783 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB004005, HPA006641, CAB044060, CAB062563, CAB068232 Supported Supported Tissue enhanced 0 rectum: 21.8;stomach: 20.7 colon: 17.3 -LRRC16A CARMIL, CARMIL1, dJ501N12.1, FLJ20048, LRRC16 ENSG00000079691 Leucine rich repeat containing 16A 6 25279078-25620530 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029038, HPA029039 Supported Supported Cytosol Mixed testis: 22.2 -PGM1 ENSG00000079739 Phosphoglucomutase 1 1 63593276-63660245 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004666, HPA024190, HPA024637, HPA046329 Approved Validated Actin filaments Expressed in all skeletal muscle: 513.0 -DDX1 DBP-RB ENSG00000079785 DEAD (Asp-Glu-Ala-Asp) box helicase 1 2 15591178-15631111 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012280, HPA034502, HPA034503 Supported Validated Nucleoplasm
Cytosol Expressed in all parathyroid gland: 143.2 -DNM2 CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII ENSG00000079805 Dynamin 2 19 10718079-10833488 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054246 Supported Approved Golgi apparatus
Cytosol Expressed in all colon: 106.7 -EPB41L2 4.1-G ENSG00000079819 Erythrocyte membrane protein band 4.1-like 2 6 130839347-131063322 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005730, HPA006642 Supported Validated Nucleus
Plasma membrane
Cell Junctions Expressed in all cerebral cortex: 139.6 -RIMS1 CORD7, KIAA0340, RAB3IP2, RIM, RIM1 ENSG00000079841 Regulating synaptic membrane exocytosis 1 6 71886703-72403143 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 30.3 testis: 7.4 -MOXD1 dJ248E1.1, DKFZP564G202, MOX ENSG00000079931 Monooxygenase, DBH-like 1 6 132296055-132401545 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035740 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 endometrium: 105.3;smooth muscle: 113.0 seminal vesicle: 53.1 -STX7 ENSG00000079950 Syntaxin 7 6 132445867-132513198 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001467, CAB062564 Supported Validated Lysosomes Expressed in all lymph node: 92.5 -RABL2B ENSG00000079974 RAB, member of RAS oncogene family-like 2B 22 50767501-50783663 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042700, HPA044007 Approved Uncertain Plasma membrane
Cytosol Expressed in all epididymis: 109.0 -KEAP1 INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454 ENSG00000079999 Kelch-like ECH-associated protein 1 19 10486120-10503741 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005558, CAB025337 Approved Supported Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all skeletal muscle: 49.4 -DDX43 CT13, DKFZp434H2114, HAGE ENSG00000080007 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 6 73394748-73417569 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA031380, HPA031381 Approved Tissue enriched 5 testis: 34.5 placenta: 6.8 -PTPRH SAP-1 ENSG00000080031 Protein tyrosine phosphatase, receptor type, H 19 55181248-55209506 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042300 Approved Mitochondria Tissue enhanced 0 duodenum: 70.8;small intestine: 78.5 gallbladder: 38.8 -DCT TYRP2 ENSG00000080166 Dopachrome tautomerase 13 94436808-94479682 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA010743, HPA010800, CAB017634 Supported Tissue enriched 32 skin: 127.2 breast: 4.0 -SLC35C2 bA394O2.1, C20orf5, CGI-15, OVCOV1 ENSG00000080189 Solute carrier family 35 (GDP-fucose transporter), member C2 20 46345980-46364458 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA027011 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all fallopian tube: 36.6 -CRYBG3 DKFZp667G2110 ENSG00000080200 Beta-gamma crystallin domain containing 3 3 97822040-97944963 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044122 Approved Nucleoplasm
Cytosol Tissue enhanced 0 thyroid gland: 45.2 testis: 25.3 -EPHA6 FLJ35246 ENSG00000080224 EPH receptor A6 3 96814581-97752460 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA007397, HPA058047 Uncertain Validated Nucleoplasm Tissue enhanced 0 ovary: 7.7;testis: 15.1 cerebral cortex: 3.6 -SCTR ENSG00000080293 Secretin receptor 2 119439843-119525301 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA007269 Uncertain Tissue enhanced 0 duodenum: 27.4;lung: 13.0;pancreas: 14.3 stomach: 4.2 -RFX3 ENSG00000080298 Regulatory factor X, 3 (influences HLA class II expression) 9 3218297-3526004 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035689 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 testis: 38.4 fallopian tube: 18.1 -RIF1 FLJ10599, FLJ12870 ENSG00000080345 Replication timing regulatory factor 1 2 151409883-151508013 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036887, HPA036888 Supported Uncertain Nucleus
Nuclear bodies
Plasma membrane Expressed in all testis: 21.1 -RAB21 KIAA0118 ENSG00000080371 RAB21, member RAS oncogene family 12 71754874-71800285 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016988, CAB037048 Approved Mixed parathyroid gland: 12.1 -SLC4A4 hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5 ENSG00000080493 Solute carrier family 4 (sodium bicarbonate cotransporter), member 4 4 71187286-71572087 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022493, HPA035628, HPA035629 Supported Tissue enhanced 0 kidney: 124.6 cerebral cortex: 57.5 -SMARCA2 BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2 ENSG00000080503 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 9 2015219-2193624 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029981, CAB037276 Supported Approved Nucleoplasm
Vesicles
Intermediate filaments Expressed in all parathyroid gland: 353.9 -RDH8 PRRDH, SDR28C2 ENSG00000080511 Retinol dehydrogenase 8 (all-trans) 19 10013249-10022279 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Group enriched 13 kidney: 1.9;testis: 1.9 appendix: 0.1 -SESN1 PA26, SEST1 ENSG00000080546 Sestrin 1 6 108986437-109094819 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA073659 Supported Nucleus
Nucleoli fibrillar center Expressed in all testis: 78.5 -MID2 FXY2, MRX101, RNF60, TRIM1 ENSG00000080561 Midline 2 X 107825755-107927193 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed smooth muscle: 23.1 -PIH1D3 CXorf41, MGC35261, NYSAR97 ENSG00000080572 PIH1 domain containing 3 X 107206632-107244243 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051099 Uncertain Group enriched 8 fallopian tube: 17.3;testis: 13.7 lung: 1.9 -COL5A3 ENSG00000080573 Collagen, type V, alpha 3 19 9959561-10010471 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048256 Approved Tissue enhanced 0 placenta: 47.4 adipose tissue: 30.9 -SRCAP DOMO1, EAF1, KIAA0309, SWR1 ENSG00000080603 Snf2-related CREBBP activator protein 16 30698209-30741409 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028929 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 54.9 -PUM3 HA-8, hPUF-A, KIAA0020, PEN, PUF6, XTP5 ENSG00000080608 Pumilio RNA-binding family member 3 9 2720469-2844241 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002353 Approved Supported Nucleoli Expressed in all appendix: 29.3 -CPB2 CPU, PCPB, TAFI ENSG00000080618 Carboxypeptidase B2 (plasma) 13 46053186-46105076 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004146 Approved Tissue enriched 28 liver: 754.0 lung: 26.5 -CHRNA3 ENSG00000080644 Cholinergic receptor, nicotinic, alpha 3 (neuronal) 15 78593052-78621295 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029430 Approved Tissue enriched 7 adrenal gland: 48.2 appendix: 6.5 -KCNN2 hSK2, KCa2.2 ENSG00000080709 Potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 5 114360945-114496500 Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038221 Uncertain Uncertain Nucleoplasm
Cytosol Tissue enhanced 0 adrenal gland: 27.4;prostate: 18.5 liver: 15.9 -CNOT4 CLONE243, NOT4, NOT4H ENSG00000080802 CCR4-NOT transcription complex, subunit 4 7 135361795-135510127 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005737 Approved Expressed in all testis: 33.2 -PSEN1 AD3, FAD, PS1, S182 ENSG00000080815 Presenilin 1 14 73136418-73223691 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006844, HPA030760, HPA067496 Approved Approved Nucleus
Golgi apparatus
Cell Junctions Expressed in all cerebral cortex: 66.1 -CPOX CPO, CPX, HCP ENSG00000080819 Coproporphyrinogen oxidase 3 98521132-98593723 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015736, HPA054448 Validated Mitochondria Expressed in all bone marrow: 25.5 -CLDND1 C3orf4 ENSG00000080822 Claudin domain containing 1 3 98497912-98523066 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029841 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all cerebral cortex: 400.9 -MOK RAGE, RAGE1, STK30 ENSG00000080823 MOK protein kinase 14 102224500-102305200 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA027282, HPA027292 Approved Supported Endoplasmic reticulum Tissue enhanced 0 testis: 71.5 fallopian tube: 33.7 -HSP90AA1 FLJ31884, Hsp89, Hsp90, HSP90N, HSPC1, HSPCA ENSG00000080824 Heat shock protein 90kDa alpha (cytosolic), class A member 1 14 102080738-102139699 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002058 Approved Supported Cytosol Expressed in all cerebral cortex: 1024.3 -RBL1 cp107, p107, PRB1 ENSG00000080839 Retinoblastoma-like 1 20 36996349-37095995 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054962, HPA056525 Supported Validated Nucleoplasm Mixed bone marrow: 9.2 -DLGAP4 DAP4, KIAA0964, SAPAP4 ENSG00000080845 Discs, large (Drosophila) homolog-associated protein 4 20 36306336-36528637 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054105, HPA056378 Approved Approved Nucleoplasm
Focal adhesion sites
Cytosol Expressed in all smooth muscle: 60.9 -IGSF9B KIAA1030 ENSG00000080854 Immunoglobulin superfamily, member 9B 11 133908564-133956985 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA010744, HPA010802 Uncertain Approved Cytosol Mixed cerebral cortex: 9.0 -CFHR2 CFHL2, FHR2, HFL3 ENSG00000080910 Complement factor H-related 2 1 196943772-196959226 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038915, HPA040726, HPA049813 Supported Tissue enriched 4655 liver: 465.5 epididymis: 0.0 -NDC80 HEC, HEC1, hsNDC80, KNTC2, TID3 ENSG00000080986 NDC80 kinetochore complex component 18 2571511-2616635 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066330 Supported Nucleoplasm
Centrosome Mixed testis: 27.2 -AP4E1 AP-4-EPSILON, SPG51 ENSG00000081014 Adaptor-related protein complex 4, epsilon 1 subunit 15 50908672-51005900 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041749, HPA041891 Approved Mixed parathyroid gland: 11.8 -RSBN1 FLJ11220, ROSBIN ENSG00000081019 Round spermatid basic protein 1 1 113761832-113812476 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042124, HPA049484 Approved Supported Nucleoplasm
Nuclear bodies
Vesicles Expressed in all bone marrow: 21.9 -MAGI3 MAGI-3 ENSG00000081026 Membrane associated guanylate kinase, WW and PDZ domain containing 3 1 113390749-113685923 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007923, HPA008444 Approved Supported Cell Junctions Mixed lung: 20.9 -CXCL2 CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, SCYB2 ENSG00000081041 Chemokine (C-X-C motif) ligand 2 4 74097035-74099293 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed liver: 110.1 -AFP FETA, HPAFP ENSG00000081051 Alpha-fetoprotein 4 73431138-73456174 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010607, HPA023600, CAB024283, CAB025339 Approved Validated Cytosol Tissue enhanced 0 liver: 1.9 breast: 0.4 -COL4A4 CA44 ENSG00000081052 Collagen, type IV, alpha 4 2 227002711-227164113 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed thyroid gland: 14.0 -TCF7 TCF-1 ENSG00000081059 Transcription factor 7 (T-cell specific, HMG-box) 5 134114711-134151865 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019403, HPA058863, HPA070505 Supported Validated Nucleoplasm Tissue enhanced 0 lymph node: 111.6 appendix: 74.8 -OSTM1 GL, HSPC019 ENSG00000081087 Osteopetrosis associated transmembrane protein 1 6 108041409-108165854 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010851 Uncertain Approved Nucleus
Vesicles
Cytosol Expressed in all smooth muscle: 33.3 -CDH7 ENSG00000081138 Cadherin 7, type 2 18 65750252-65890341 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA061419 Approved Tissue enhanced 0 cerebral cortex: 2.8;prostate: 1.2 testis: 0.7 -IMPG2 IPM200, RP56 ENSG00000081148 Interphotoreceptor matrix proteoglycan 2 3 101222546-101320560 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008779, HPA015907 Supported Tissue enriched 44 fallopian tube: 15.5 spleen: 0.3 -PCNP ENSG00000081154 PEST proteolytic signal containing nuclear protein 3 101574095-101594437 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035011 Supported Supported Nucleus Expressed in all endometrium: 80.2 -EXD2 C14orf114, EXDL2, FLJ10738 ENSG00000081177 Exonuclease 3'-5' domain containing 2 14 69191511-69244020 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002906, HPA005848 Uncertain Approved Intermediate filaments
Mitochondria Expressed in all testis: 36.4 -ARG2 ENSG00000081181 Arginase 2 14 67619798-67651720 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000663, CAB009435 Supported Supported Mitochondria Tissue enhanced 0 parathyroid gland: 96.3;prostate: 165.6;thyroid gland: 157.3 kidney: 63.5 -MEF2C ENSG00000081189 Myocyte enhancer factor 2C 5 88717117-88904257 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005533, CAB068196, CAB068197 Supported Supported Nucleoplasm
Vesicles Expressed in all cerebral cortex: 221.1 -PTPRC CD45, GP180, LCA, T200 ENSG00000081237 Protein tyrosine phosphatase, receptor type, C 1 198638671-198757283 Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB000052, HPA000440, CAB002800, CAB056154, CAB068221 Supported Expressed in all lymph node: 378.0 -CACNA1S CACNL1A3, Cav1.1, HOKPP, hypoPP, MHS5 ENSG00000081248 Calcium channel, voltage-dependent, L type, alpha 1S subunit 1 201039512-201112566 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009507, HPA048892, HPA056815 Supported Tissue enriched 34 skeletal muscle: 103.0 esophagus: 3.0 -PKP1 B6P ENSG00000081277 Plakophilin 1 1 201283452-201332993 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027221, HPA027589 Approved Validated Nucleoplasm Group enriched 11 esophagus: 282.7;skin: 823.7 prostate: 51.8 -UBA5 FLJ23251, UBE1DC1 ENSG00000081307 Ubiquitin-like modifier activating enzyme 5 3 132654446-132678097 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017235 Uncertain Validated Vesicles
Cytosol Expressed in all parathyroid gland: 63.1 -STK17B DRAK2 ENSG00000081320 Serine/threonine kinase 17b 2 196133566-196176503 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034858 Approved Uncertain Plasma membrane
Cytosol Tissue enhanced 0 bone marrow: 248.9 lymph node: 135.0 -CDC14B Cdc14B1, Cdc14B2, CDC14B3, hCDC14B ENSG00000081377 Cell division cycle 14B 9 96490241-96619830 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA013312 Approved Supported Nuclear membrane Mixed testis: 18.5 -ZNF510 KIAA0972 ENSG00000081386 Zinc finger protein 510 9 96755865-96778129 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA049139 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all parathyroid gland: 12.2 -LRP2 DBS, gp330 ENSG00000081479 Low density lipoprotein receptor-related protein 2 2 169127109-169362685 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005980, HPA064792 Supported Approved Vesicles
Mitochondria Group enriched 6 kidney: 49.4;parathyroid gland: 153.0;thyroid gland: 36.8 breast: 14.1 -ZNF506 DKFZp761G1812 ENSG00000081665 Zinc finger protein 506 19 19785839-19821751 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all thyroid gland: 16.2 -JMJD4 FLJ12517 ENSG00000081692 Jumonji domain containing 4 1 227730425-227735411 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027260, HPA052861 Uncertain Approved Vesicles
Plasma membrane Expressed in all testis: 12.9 -DUSP12 DUSP1, YVH1 ENSG00000081721 Dual specificity phosphatase 12 1 161749758-161757238 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008840 Uncertain Supported Nucleus Expressed in all bone marrow: 20.4 -AACS ACSF1, FLJ12389, SUR-5 ENSG00000081760 Acetoacetyl-CoA synthetase 12 125065379-125143333 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058815 Approved Approved Vesicles Expressed in all breast: 54.1 -KIAA0141 DELE ENSG00000081791 KIAA0141 5 141923808-141942047 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036548, HPA061490 Uncertain Uncertain Nucleoplasm
Golgi apparatus Expressed in all spleen: 63.3 -SLC13A1 NAS1, NaSi-1 ENSG00000081800 Solute carrier family 13 (sodium/sulfate symporter), member 1 7 123113531-123199986 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA053615, HPA062714 Approved Tissue enriched 6 kidney: 84.4 small intestine: 14.3 -CADPS2 ENSG00000081803 Ca++-dependent secretion activator 2 7 122318425-122886759 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056398 Approved Nucleoplasm
Vesicles Mixed parathyroid gland: 44.9 -PCDHB4 PCDH-BETA4 ENSG00000081818 Protocadherin beta 4 5 141121799-141125623 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014466 Approved Uncertain Plasma membrane
Intermediate filaments
Cytosol Mixed endometrium: 8.9 -PCDHA6 CNR2, CNRS2, CRNR2, PCDH-ALPHA6 ENSG00000081842 Protocadherin alpha 6 5 140827958-141012344 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059326 Approved Vesicles Tissue enhanced 0 cerebral cortex: 4.8 parathyroid gland: 1.9 -PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 Protocadherin gamma subfamily A, 2 5 141338760-141512979 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008755 Uncertain Mixed cerebral cortex: 8.5 -HSPB11 C1orf41, HSPCO34, IFT25, PP25 ENSG00000081870 Heat shock protein family B (small), member 11 1 53916574-53945929 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030140 Uncertain Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 116.2 -PHLPP1 KIAA0606, PHLPP, PLEKHE1, SCOP ENSG00000081913 PH domain and leucine rich repeat protein phosphatase 1 18 62715450-62980433 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020200 Uncertain Expressed in all cerebral cortex: 41.0 -ATP8B1 ATPIC, BRIC, FIC1, PFIC, PFIC1 ENSG00000081923 ATPase, aminophospholipid transporter, class I, type 8B, member 1 18 57646426-57803101 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018673, HPA018674 Supported Expressed in all colon: 96.9 -IL12RB2 ENSG00000081985 Interleukin 12 receptor, beta 2 1 67307364-67396900 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024168 Uncertain Uncertain Plasma membrane
Cytosol Tissue enhanced 0 placenta: 11.7 cerebral cortex: 4.5 -SMARCD3 BAF60C, CRACD3, Rsc6p ENSG00000082014 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 7 151238764-151277896 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063955, HPA065517 Uncertain Validated Nucleoplasm Mixed cerebral cortex: 82.9 -WDR70 FLJ10233 ENSG00000082068 WD repeat domain 70 5 37379212-37753435 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043064, HPA048149 Uncertain Approved Mitochondria
Cytosol Expressed in all endometrium: 18.3 -FYB FYB-120/130, SLAP-130 ENSG00000082074 FYN binding protein 5 39105236-39274528 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025336, HPA026796 Supported Approved Plasma membrane Tissue enhanced 0 appendix: 131.1;lymph node: 111.3;spleen: 116.6 tonsil: 67.0 -MPP4 DLG6 ENSG00000082126 Membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2 201644870-201698694 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036387 Approved Nucleoplasm
Vesicles
Cytosol Tissue enhanced 0 skin: 1.0;testis: 1.2 adrenal gland: 0.4 -STRADB ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK ENSG00000082146 STE20-related kinase adaptor beta 2 201387858-201480846 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026549, HPA028520 Approved Supported Aggresome
Cytosol Expressed in all kidney: 72.8 -BZW1 BZAP45, KIAA0005 ENSG00000082153 Basic leucine zipper and W2 domains 1 2 200810594-200827338 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047288, HPA053272 Uncertain Approved Vesicles Expressed in all testis: 310.4 -PGR NR3C3, PR ENSG00000082175 Progesterone receptor 11 101029624-101130524 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000068, HPA004751, HPA008428, HPA017176, CAB055100 Supported Group enriched 6 cervix, uterine: 95.8;endometrium: 171.3;fallopian tube: 52.8;smooth muscle: 113.5 ovary: 19.4 -C1QTNF3 2310005P21Rik, Corcs, Cors, Cors-26, CTRP3 ENSG00000082196 C1q and tumor necrosis factor related protein 3 5 34019448-34043832 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064996, HPA066011 Uncertain Approved Golgi apparatus Tissue enhanced 0 esophagus: 39.0 smooth muscle: 32.6 -ME2 ENSG00000082212 Malic enzyme 2, NAD(+)-dependent, mitochondrial 18 50879049-50954257 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008247, HPA008880 Supported Validated Mitochondria Expressed in all spleen: 54.3 -C5orf22 FLJ11193 ENSG00000082213 Chromosome 5 open reading frame 22 5 31532266-31555058 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043062 Approved Approved Nuclear membrane Expressed in all parathyroid gland: 13.4 -CCNT2 ENSG00000082258 Cyclin T2 2 134918235-134959342 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005559 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 27.7 -FAM135A FLJ20176, KIAA1411 ENSG00000082269 Family with sequence similarity 135, member A 6 70412941-70561174 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031743, HPA031744 Approved Approved Nucleoplasm
Cytosol Mixed esophagus: 33.5 -COL19A1 ENSG00000082293 Collagen, type XIX, alpha 1 6 69866571-70209976 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042422 Uncertain Tissue enhanced 0 lymph node: 3.2;tonsil: 3.0 spleen: 2.1 -EPB41L3 4.1B, DAL1, KIAA0987 ENSG00000082397 Erythrocyte membrane protein band 4.1-like 3 18 5392381-5630700 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028605 Approved Validated Plasma membrane Expressed in all testis: 121.4 -COBLL1 KIAA0977 ENSG00000082438 Cordon-bleu WH2 repeat protein-like 1 2 164653624-164843679 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044933, HPA053344 Supported Approved Nucleus
Plasma membrane
Cytosol Mixed placenta: 76.5 -DLG3 KIAA1232, MRX90, NE-Dlg, NEDLG, PPP1R82, SAP-102, SAP102 ENSG00000082458 Discs, large homolog 3 (Drosophila) X 70444861-70505490 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001733, HPA078130 Approved Approved Nucleus
Nucleoli Mixed parathyroid gland: 36.0 -KCNK2 K2p2.1, TREK-1 ENSG00000082482 Potassium channel, two pore domain subfamily K, member 2 1 215005775-215237093 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056054 Uncertain Approved Mitochondria
Cytosol Tissue enhanced 0 adrenal gland: 75.5 thyroid gland: 17.3 -SERTAD4 DJ667H12.2 ENSG00000082497 SERTA domain containing 4 1 210232799-210246631 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA027344, HPA028514 Uncertain Supported Nucleoplasm Mixed breast: 4.6 -TRAF5 RNF84 ENSG00000082512 TNF receptor-associated factor 5 1 211326615-211374946 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008052, CAB010277 Supported Supported Cytosol Mixed lymph node: 35.5 -MRPL22 HSPC158, MRP-L25, RPML25 ENSG00000082515 Mitochondrial ribosomal protein L22 5 154941070-154969411 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047063 Uncertain Approved Mitochondria Expressed in all testis: 62.7 -GEMIN5 ENSG00000082516 Gem (nuclear organelle) associated protein 5 5 154887416-154938209 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037392, HPA037393 Uncertain Validated Nuclear bodies
Cytosol Expressed in all parathyroid gland: 12.4 -OPRK1 KOR, OPRK ENSG00000082556 Opioid receptor, kappa 1 8 53225716-53251697 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB022595 Uncertain Group enriched 7 cerebral cortex: 3.6;prostate: 3.2;testis: 1.8 skeletal muscle: 0.3 -NFE2L1 FLJ00380, LCR-F1, NRF1, TCF11 ENSG00000082641 Nuclear factor, erythroid 2-like 1 17 48048329-48061487 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA063384, HPA065424 Approved Approved Nucleus
Cytosol Expressed in all skeletal muscle: 468.1 -SEMA5B FLJ10372, KIAA1445, SEMAG, SemG ENSG00000082684 Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B 3 122909193-123028605 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA017084, HPA066548 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 11.5 heart muscle: 4.2 -GSK3B ENSG00000082701 Glycogen synthase kinase 3 beta 3 119821323-120094417 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016263, HPA028017 Approved Validated Nucleus Expressed in all testis: 47.2 -ITGB5 ENSG00000082781 Integrin, beta 5 3 124761948-124901418 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001820, CAB022050 Approved Approved Plasma membrane
Mitochondria Expressed in all placenta: 116.8 -ERC1 CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2 ENSG00000082805 ELKS/RAB6-interacting/CAST family member 1 12 990509-1495933 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019513, HPA019523, HPA024130 Approved Supported Vesicles
Plasma membrane
Cytosol Mixed parathyroid gland: 17.1 -XPO1 CRM1, emb ENSG00000082898 Exportin 1 2 61477849-61538626 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010184, HPA042933 Supported Validated Nucleoplasm
Nuclear membrane
Vesicles
Cytosol Expressed in all testis: 138.5 -RNF13 RZF ENSG00000082996 Ring finger protein 13 3 149812708-149962139 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064784 Approved Nucleoplasm
Vesicles
Cytosol Expressed in all thyroid gland: 94.0 -TRPM3 GON-2, KIAA1616, LTRPC3 ENSG00000083067 Transient receptor potential cation channel, subfamily M, member 3 9 70529063-71446904 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 kidney: 17.5 testis: 6.3 -PALB2 FANCN, FLJ21816 ENSG00000083093 Partner and localizer of BRCA2 16 23603160-23641310 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB014895, HPA057000 Approved Supported Nucleoplasm Mixed testis: 14.4 -DOPEY1 dJ202D23.2, KIAA1117 ENSG00000083097 Dopey family member 1 6 83067666-83171350 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027902, HPA027904 Approved Approved Nucleus Mixed parathyroid gland: 25.0 -LYRM2 DJ122O8.2 ENSG00000083099 LYR motif containing 2 6 89568144-89638753 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063932 Uncertain Approved Cytosol Expressed in all thyroid gland: 42.4 -BCKDHB ENSG00000083123 Branched chain keto acid dehydrogenase E1, beta polypeptide 6 80106647-80346270 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031580 Approved Expressed in all liver: 39.8 -KAT6A MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220 ENSG00000083168 K(lysine) acetyltransferase 6A 8 41929479-42051990 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017023, HPA063266, HPA065052 Supported Approved Nucleoli
Nuclear speckles
Cytosol Expressed in all parathyroid gland: 33.9 -ZCCHC6 FLJ13409, KIAA1711, PAPD6, TUT7 ENSG00000083223 Zinc finger, CCHC domain containing 6 9 86287733-86354454 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020615, HPA020620 Approved Supported Nucleoplasm
Cytosol Expressed in all prostate: 37.1 -ULK2 ATG1B, KIAA0623, Unc51.2 ENSG00000083290 Unc-51 like autophagy activating kinase 2 17 19770829-19867936 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009027, CAB037021 Approved Expressed in all testis: 65.7 -GRHL2 BOM, DFNA28, FLJ13782, TFCP2L3 ENSG00000083307 Grainyhead-like transcription factor 2 8 101492432-101669726 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004820, HPA062839 Uncertain Supported Nucleoplasm Tissue enhanced 0 prostate: 38.8 skin: 34.0 -TNPO1 IPO2, KPNB2, MIP, MIP1, TRN ENSG00000083312 Transportin 1 5 72816312-72916733 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016325 Approved Supported Nucleoplasm
Cytosol
Cytoplasmic bodies Expressed in all parathyroid gland: 108.4 -PLOD1 LH1, LLH, PLOD ENSG00000083444 Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 1 11934205-11975538 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049137, HPA055799 Uncertain Uncertain Nucleoplasm
Vesicles Expressed in all placenta: 121.3 -P2RX5 LRH-1, P2X5 ENSG00000083454 Purinergic receptor P2X, ligand gated ion channel, 5 17 3672199-3696404 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA021948, HPA067827 Supported Supported Cytosol Group enriched 10 appendix: 42.6;lymph node: 90.9;spleen: 75.5;tonsil: 48.4 bone marrow: 6.2 -ITGAE CD103, HUMINAE ENSG00000083457 Integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 17 3714628-3801243 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB026461, HPA036313 Approved Tissue enhanced 0 lung: 9.5 small intestine: 6.4 -DIS3 dis3p, EXOSC11, KIAA1008, RRP44 ENSG00000083520 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease 13 72752169-72782096 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039281, HPA058762 Approved Validated Nucleus
Cytosol Expressed in all testis: 38.5 -PIBF1 C13orf24, CEP90 ENSG00000083535 Progesterone immunomodulatory binding factor 1 13 72782059-73016461 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052269, HPA066120, HPA066125 Approved Supported Nucleoplasm
Microtubule organizing center Expressed in all testis: 25.7 -TDRD3 FLJ21007 ENSG00000083544 Tudor domain containing 3 13 60396457-60573878 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034925 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 22.7 -NUFIP1 NUFIP ENSG00000083635 Nuclear fragile X mental retardation protein interacting protein 1 13 44939249-44989483 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029958, HPA029959 Approved Validated Nucleus
Nucleoli Mixed testis: 10.2 -PDS5B APRIN, AS3, CG008, FLJ23236, KIAA0979 ENSG00000083642 PDS5 cohesin associated factor B 13 32586427-32778019 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039513, HPA040015 Supported Validated Nucleoplasm Expressed in all endometrium: 31.1 -OXCT1 OXCT, SCOT ENSG00000083720 3-oxoacid CoA transferase 1 5 41730065-41870519 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012047, HPA061425 Supported Validated Mitochondria Tissue enhanced 0 heart muscle: 153.6 cerebral cortex: 99.0 -RRAGB ENSG00000083750 Ras-related GTP binding B X 55717739-55758774 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003734 Approved Approved Golgi apparatus
Vesicles Expressed in all epididymis: 41.5 -EPYC DSPG3, Pg-Lb, SLRR3B ENSG00000083782 Epiphycan 12 90963679-91005026 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038212, HPA045455 Approved Tissue enriched 6 placenta: 8.8 endometrium: 1.5 -CYLD CYLD1, KIAA0849, USPL2 ENSG00000083799 Cylindromatosis (turban tumor syndrome) 16 50742050-50801935 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011713, HPA050095 Approved Supported Nucleoplasm
Microtubule organizing center Expressed in all testis: 70.2 -SLC27A5 ACSB, ACSVL6, FACVL3, FATP5, FLJ22987, VLACSR, VLCS-H2, VLCSH2 ENSG00000083807 Solute carrier family 27 (fatty acid transporter), member 5 19 58479512-58512413 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007292, CAB056160, CAB068239 Supported Tissue enriched 23 liver: 335.8 fallopian tube: 14.4 -ZNF324 ZF5128, ZNF324A ENSG00000083812 Zinc finger protein 324 19 58467045-58475436 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA039774 Uncertain Approved Nucleus
Nuclear membrane
Cytosol Mixed cerebral cortex: 8.6 -ZNF671 FLJ23506 ENSG00000083814 Zinc finger protein 671 19 57719751-57727624 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046099 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 16.4 -ZNF416 FLJ20557 ENSG00000083817 Zinc finger protein 416 19 57571566-57578927 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA063318 Approved Nuclear bodies
Cytosol Mixed testis: 7.8 -ZNF586 FLJ20070 ENSG00000083828 Zinc finger protein 586 19 57769655-57819939 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA030306, HPA060782 Approved Approved Nucleoli fibrillar center
Vesicles Expressed in all bone marrow: 16.3 -ZNF446 FLJ20626, ZKSCAN20, ZSCAN52 ENSG00000083838 Zinc finger protein 446 19 58474017-58481230 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052786 Approved Nuclear speckles Mixed fallopian tube: 12.1 -ZNF264 KIAA0412 ENSG00000083844 Zinc finger protein 264 19 57191500-57222846 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057665 Uncertain Expressed in all testis: 18.3 -RPS5 S5 ENSG00000083845 Ribosomal protein S5 19 58386400-58394806 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055878, HPA061979 Supported Supported Endoplasmic reticulum
Cytosol Expressed in all ovary: 2644.2 -FAT1 CDHF7, CDHR8, FAT ENSG00000083857 FAT atypical cadherin 1 4 186587783-186726722 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001869, HPA023882 Approved Mixed gallbladder: 37.4 -YTHDC1 KIAA1966, YT521, YT521-B ENSG00000083896 YTH domain containing 1 4 68310387-68350089 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036462 Supported Approved Nucleoplasm
Plasma membrane Expressed in all bone marrow: 75.2 -CHMP2B CHMP2.5, DKFZP564O123, VPS2B ENSG00000083937 Charged multivesicular body protein 2B 3 87227271-87255548 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035069, HPA052754 Uncertain Supported Cytosol Expressed in all thyroid gland: 78.2 -SMAP2 SMAP1L ENSG00000084070 Small ArfGAP2 1 40344850-40423326 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021466, HPA024424 Approved Expressed in all lymph node: 235.7 -PPIE CyP-33, MGC111222, MGC3736 ENSG00000084072 Peptidylprolyl isomerase E (cyclophilin E) 1 39692182-39763914 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019357, HPA020131 Approved Supported Nuclear speckles Expressed in all fallopian tube: 66.4 -ZMPSTE24 FACE-1, HGPS, PRO1, STE24, Ste24p ENSG00000084073 Zinc metallopeptidase STE24 1 40258107-40294184 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006988 Approved Approved Golgi apparatus
Cytosol Expressed in all parathyroid gland: 89.0 -STARD7 GTT1 ENSG00000084090 StAR-related lipid transfer (START) domain containing 7 2 96184859-96208825 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033965, HPA064958, HPA064978 Supported Approved Mitochondria Expressed in all parathyroid gland: 106.6 -NOA1 C4orf14, hAtNOS1, hNOA1, MGC3232, MTG3 ENSG00000084092 Nitric oxide associated 1 4 56963370-56978823 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035838, HPA035839 Approved Supported Mitochondria Expressed in all fallopian tube: 16.8 -REST NRSF, XBR ENSG00000084093 RE1-silencing transcription factor 4 56907876-56935844 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006079, CAB068222 Supported Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 31.6 -HAL HIS ENSG00000084110 Histidine ammonia-lyase 12 95972662-95996365 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038547, HPA038548 Supported Uncertain Cytosol Group enriched 8 liver: 51.0;skin: 72.6 bone marrow: 7.4 -SSH1 KIAA1298 ENSG00000084112 Slingshot protein phosphatase 1 12 108778192-108857590 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019845 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Mixed parathyroid gland: 9.5 -GSTP1 FAEES3, GST3, GSTP ENSG00000084207 Glutathione S-transferase pi 1 11 67583595-67586660 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019779, HPA019869 Approved Supported Mitochondria
Cytosol Expressed in all esophagus: 1064.0 -APLP2 APPH, APPL2 ENSG00000084234 Amyloid beta (A4) precursor-like protein 2 11 130069837-130144811 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039319 Approved Approved Vesicles Expressed in all thyroid gland: 1052.3 -FAM234B KIAA1467 ENSG00000084444 Family with sequence similarity 234, member B 12 13044284-13142521 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010803 Approved Endoplasmic reticulum Tissue enhanced 0 cerebral cortex: 32.5 breast: 20.5 -SLCO1A2 OATP, OATP-A, OATP1A2, SLC21A3 ENSG00000084453 Solute carrier organic anion transporter family, member 1A2 12 21264600-21419594 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA071152 Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 28.8 salivary gland: 6.6 -WBP11 NPWBP, PPP1R165, SIPP1 ENSG00000084463 WW domain binding protein 11 12 14784579-14803540 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039710, HPA040037, HPA046403, HPA049126 Approved Validated Nucleoplasm Expressed in all testis: 68.8 -EIF3I eIF3-beta, eIF3-p36, eIF3i, EIF3S2, TRIP-1 ENSG00000084623 Eukaryotic translation initiation factor 3, subunit I 1 32221928-32231604 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029939, HPA029940 Supported Uncertain Nucleoplasm
Cytosol Expressed in all fallopian tube: 197.3 -NKAIN1 FAM77C, FLJ12650 ENSG00000084628 Na+/K+ transporting ATPase interacting 1 1 31179745-31239554 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA006873 Uncertain Tissue enhanced 0 adrenal gland: 13.9;cerebral cortex: 13.1;skeletal muscle: 7.4 epididymis: 4.4 -COL16A1 ENSG00000084636 Collagen, type XVI, alpha 1 1 31652247-31704319 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027235, HPA027237 Approved Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 ovary: 181.4 cervix: 127.5 -TXLNA DKFZp451J0118 ENSG00000084652 Taxilin alpha 1 32179686-32198285 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045383, HPA072477 Supported Approved Nucleoplasm
Centrosome
Cytosol Expressed in all parathyroid gland: 48.0 -APOB ENSG00000084674 Apolipoprotein B 2 21001429-21044073 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016070, HPA049793 Supported Supported Vesicles
Cytosol Group enriched 122 duodenum: 187.7;liver: 619.0;small intestine: 340.0 adipose tissue: 3.1 -NCOA1 bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1 ENSG00000084676 Nuclear receptor coactivator 1 2 24491914-24770702 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019402, HPA070213, HPA070520 Supported Validated Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 58.0 -AGBL5 CCP5, FLJ21839 ENSG00000084693 ATP/GTP binding protein-like 5 2 27042364-27070622 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030981 Uncertain Approved Cytosol Tissue enriched 6 testis: 357.5 parathyroid gland: 57.3 -EFR3B FLJ37871, KIAA0953 ENSG00000084710 EFR3 homolog B 2 25042130-25159137 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038088, HPA038089 Uncertain Approved Nucleus Tissue enhanced 0 cerebral cortex: 33.3 skeletal muscle: 6.8 -KIF3C ENSG00000084731 Kinesin family member 3C 2 25926596-25982749 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035755 Approved Nuclear membrane
Nuclear bodies
Intermediate filaments Tissue enriched 13 cerebral cortex: 133.6 adrenal gland: 10.0 -RAB10 ENSG00000084733 RAB10, member RAS oncogene family 2 26034107-26137454 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045611 Approved Expressed in all esophagus: 186.4 -GCKR ENSG00000084734 Glucokinase (hexokinase 4) regulator 2 27496842-27523684 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB034098, HPA064305 Supported Approved Intermediate filaments Tissue enriched 7 liver: 44.2 stomach: 6.2 -HADHA GBP, LCEH, LCHAD, MTPA ENSG00000084754 Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 2 26190635-26244726 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015536, HPA056070 Approved Validated Mitochondria Expressed in all duodenum: 241.8 -MAPRE3 EB3, RP3 ENSG00000084764 Microtubule-associated protein, RP/EB family, member 3 2 26970612-27027196 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009263 Uncertain Supported Cytosol Tissue enhanced 0 cerebral cortex: 177.8 testis: 70.0 -CAD ENSG00000084774 Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 2 27217390-27243943 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007781, HPA057266, HPA069341 Supported Supported Nucleoplasm Expressed in all skin: 22.0 -CD59 16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20 ENSG00000085063 CD59 molecule, complement regulatory protein 11 33698261-33736445 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001448, HPA026494 Supported Approved Golgi apparatus
Vesicles Expressed in all epididymis: 907.3 -CD82 IA4, KAI1, R2, ST6, TSPAN27 ENSG00000085117 CD82 molecule 11 44564427-44620363 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002508, HPA028900, HPA061418 Supported Approved Vesicles Expressed in all esophagus: 132.1 -BCORL1 CXorf10, FLJ11362 ENSG00000085185 BCL6 corepressor-like 1 X 129981107-130058083 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031775, HPA031777, HPA068568 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all placenta: 18.2 -ATRX JMS, MRX52, RAD54, XH2, XNP ENSG00000085224 Alpha thalassemia/mental retardation syndrome X-linked X 77504878-77786269 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001906, CAB009372, HPA064684, CAB068176 Supported Supported Nuclear bodies Expressed in all parathyroid gland: 53.5 -AK6 CINAP ENSG00000085231 Adenylate kinase 6 5 69350984-69370013 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005361, HPA034935 Supported Supported Nucleoplasm Expressed in all adrenal gland: 25.2 -FCN1 FCNM ENSG00000085265 Ficolin (collagen/fibrinogen domain containing) 1 9 134905890-134917963 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000685, HPA001295, CAB016760 Supported Group enriched 5 appendix: 331.6;bone marrow: 635.8 spleen: 96.4 -MYNN SBBIZ1, ZBTB31, ZNF902 ENSG00000085274 Myoneurin 3 169772831-169789716 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045149 Approved Supported Nucleus Expressed in all testis: 18.2 -MECOM EVI1, MDS1, MDS1-EVI1, PRDM3 ENSG00000085276 MDS1 and EVI1 complex locus 3 169083499-169663618 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046537 Supported Supported Nuclear speckles Mixed stomach: 66.8 -SCAMP1 SCAMP37 ENSG00000085365 Secretory carrier membrane protein 1 5 78360583-78479071 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044753 Approved Nucleoplasm
Vesicles
Cell Junctions Expressed in all cerebral cortex: 69.4 -PREP ENSG00000085377 Prolyl endopeptidase 6 105277565-105403084 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025414, HPA031388, HPA031389, HPA031390 Supported Validated Cytosol Expressed in all rectum: 54.6 -HACE1 KIAA1320 ENSG00000085382 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 6 104728093-104859919 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046071 Supported Endoplasmic reticulum Tissue enhanced 0 placenta: 43.6 testis: 18.9 -SEH1L SEC13L, Seh1, SEH1A, SEH1B ENSG00000085415 SEH1-like nucleoporin 18 12947133-12987536 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039964 Uncertain Expressed in all cerebral cortex: 34.0 -WDR47 KIAA0893 ENSG00000085433 WD repeat domain 47 1 108970214-109042113 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027287, HPA027289 Approved Approved Actin filaments Expressed in all cerebral cortex: 73.5 -WDFY1 FENS-1, KIAA1435, WDF1, ZFYVE17 ENSG00000085449 WD repeat and FYVE domain containing 1 2 223855716-223945387 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050603 Approved Expressed in all placenta: 38.5 -OVGP1 CHIT5, MUC9 ENSG00000085465 Oviductal glycoprotein 1, 120kDa 1 111414314-111427777 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA062205 Supported Tissue enriched 117 fallopian tube: 3120.0 endometrium: 26.6 -SLC25A24 APC1, DKFZp586G0123 ENSG00000085491 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 1 108134036-108200849 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028519, HPA063636 Supported Validated Mitochondria Expressed in all cervix: 44.3 -MAP3K4 KIAA0213, MAPKKK4, MEKK4, MTK1 ENSG00000085511 Mitogen-activated protein kinase kinase kinase 4 6 160991727-161117385 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007625 Uncertain Approved Cytosol Expressed in all endometrium: 15.3 -PILRA FDF03 ENSG00000085514 Paired immunoglobin-like type 2 receptor alpha 7 100367530-100400099 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056132 Approved Tissue enhanced 0 appendix: 53.6 lung: 43.8 -IGSF9 IGSF9A, KIAA1355, Nrt1 ENSG00000085552 Immunoglobulin superfamily, member 9 1 159927039-159945604 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA037753 Uncertain Tissue enhanced 0 skin: 28.2 stomach: 13.4 -ABCB1 ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1 ENSG00000085563 ATP-binding cassette, sub-family B (MDR/TAP), member 1 7 87503633-87713323 Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB001716, HPA002199 Approved Approved Nucleoplasm
Focal adhesion sites
Cytosol Tissue enhanced 0 adrenal gland: 138.6;small intestine: 83.9 kidney: 37.0 -ZNF213 CR53, ZKSCAN21, ZSCAN53 ENSG00000085644 Zinc finger protein 213 16 3129777-3142805 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035000, HPA056750 Uncertain Approved Nucleus
Nuclear membrane
Vesicles
Cytosol Mixed testis: 16.9 -AKR1B1 ALDR1, AR ENSG00000085662 Aldo-keto reductase family 1, member B1 (aldose reductase) 7 134442350-134459284 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026425, CAB027391, CAB047353, HPA052751 Supported Supported Nucleus
Cytosol Tissue enriched 6 adrenal gland: 2498.2 seminal vesicle: 444.1 -CPNE3 ENSG00000085719 Copine III 8 86484830-86561498 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029552 Uncertain Supported Nucleus
Nucleoli
Mitochondria
Cytosol Expressed in all thyroid gland: 102.9 -RRN3 DKFZp566E104, TIF-IA ENSG00000085721 RRN3 homolog, RNA polymerase I transcription factor 16 15060022-15094317 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049837 Supported Validated Nucleoli Expressed in all parathyroid gland: 21.9 -CTTN EMS1 ENSG00000085733 Cortactin 11 70398404-70436584 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011235, HPA057242 Supported Supported Golgi apparatus
Vesicles
Plasma membrane
Cytosol Expressed in all gallbladder: 109.3 -WNT11 ENSG00000085741 Wingless-type MMTV integration site family, member 11 11 76186325-76210736 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050101, HPA063569 Uncertain Approved Centrosome
Cytosol Tissue enhanced 0 adipose tissue: 29.6;adrenal gland: 17.5 placenta: 5.7 -MTIF2 IF-2mt ENSG00000085760 Mitochondrial translational initiation factor 2 2 55236595-55269347 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006021, HPA061422 Uncertain Validated Mitochondria Expressed in all parathyroid gland: 39.8 -DDHD2 KIAA0725, SAMWD1, SPG54 ENSG00000085788 DDHD domain containing 2 8 38225218-38275558 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015202, HPA023143, HPA023147 Supported Supported Microtubule organizing center
Cytosol Expressed in all cerebral cortex: 70.1 -TTC39A C1orf34, DEME-6, KIAA0452 ENSG00000085831 Tetratricopeptide repeat domain 39A 1 51287258-51345116 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028098, HPA043440 Uncertain Approved Centrosome Tissue enhanced 0 testis: 87.2 breast: 58.0 -EPS15 AF-1P, MLLT5 ENSG00000085832 Epidermal growth factor receptor pathway substrate 15 1 51354263-51519328 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008451, CAB010164 Approved Validated Vesicles
Cytosol Expressed in all testis: 84.3 -ORC1 HSORC1, ORC1L, PARC1 ENSG00000085840 Origin recognition complex, subunit 1 1 52372829-52404459 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027450 Approved Approved Nucleus
Plasma membrane
Cytosol Tissue enhanced 0 bone marrow: 18.0 lymph node: 8.0 -MGST2 MGST-II ENSG00000085871 Microsomal glutathione S-transferase 2 4 139665768-139740745 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010707 Approved Approved Nucleoplasm Expressed in all liver: 177.4 -CHERP DAN16, ERPROT213-21 ENSG00000085872 Calcium homeostasis endoplasmic reticulum protein 19 16517889-16542530 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050647 Uncertain Expressed in all cerebral cortex: 22.2 -ATG16L1 APG16L, ATG16A, ATG16L, FLJ10035, WDR30 ENSG00000085978 Autophagy related 16-like 1 2 233210051-233295674 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012577, HPA063900 Supported Approved Cytosol Mixed testis: 12.8 -USP40 FLJ10785 ENSG00000085982 Ubiquitin specific peptidase 40 2 233475520-233566782 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005821 Uncertain Approved Vesicles Expressed in all parathyroid gland: 30.9 -POMGNT1 FLJ20277, LGMD2O, MEB, MGAT1.2 ENSG00000085998 Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1 46188682-46220305 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044518 Approved Expressed in all parathyroid gland: 121.6 -RAD54L hHR54, hRAD54, RAD54A ENSG00000085999 RAD54-like (S. cerevisiae) 1 46247688-46278473 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028954, HPA051537 Approved Validated Nucleoplasm Tissue enhanced 0 testis: 20.0 tonsil: 8.3 -MAST2 KIAA0807, MAST205 ENSG00000086015 Microtubule associated serine/threonine kinase 2 1 45786987-46036124 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039722, HPA040155 Approved Approved Cytosol Expressed in all testis: 78.5 -DNAJA1 dj-2, hdj-2, HSJ2, HSPF4, NEDD7 ENSG00000086061 DnaJ (Hsp40) homolog, subfamily A, member 1 9 33025211-33039907 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001306 Approved Supported Microtubules
Cytosol Expressed in all testis: 240.2 -B4GALT1 beta4Gal-T1, GGTB2 ENSG00000086062 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 9 33104082-33167356 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010806, HPA010807 Supported Validated Golgi apparatus Expressed in all parathyroid gland: 138.8 -CHMP5 C9orf83, CGI-34, HSPC177, SNF7DC2, Vps60 ENSG00000086065 Charged multivesicular body protein 5 9 33264879-33282069 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033874, HPA042883, HPA056437 Approved Supported Microtubules
Midbody
Cytosol Expressed in all thyroid gland: 127.0 -NFX1 MGC20369, NFX2, TEG-42, Tex42 ENSG00000086102 Nuclear transcription factor, X-box binding 1 9 33290511-33371157 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056310, HPA061382, HPA073519 Approved Validated Nucleus
Cytosol Expressed in all thyroid gland: 41.6 -AQP6 AQP2L ENSG00000086159 Aquaporin 6, kidney specific 12 49967194-49977139 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA015278 Supported Tissue enriched 9 kidney: 20.8 cerebral cortex: 2.3 -DIMT1 DIMT1L, HSA9761 ENSG00000086189 DIM1 dimethyladenosine transferase 1 homolog 5 62387254-62403939 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042944 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all cerebral cortex: 33.8 -IPO11 RanBP11 ENSG00000086200 Importin 11 5 62403972-62628582 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067097 Approved Validated Nucleus
Nucleoli fibrillar center Expressed in all testis: 40.5 -FOLH1 FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA ENSG00000086205 Folate hydrolase (prostate-specific membrane antigen) 1 11 49146635-49208670 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001451, HPA010593 Supported Group enriched 6 duodenum: 307.0;prostate: 128.9;small intestine: 93.5 cerebral cortex: 31.1 -EIF2AK1 HRI, KIAA1369 ENSG00000086232 Eukaryotic translation initiation factor 2-alpha kinase 1 7 6022244-6059230 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016496, CAB022082, HPA061675 Approved Supported Nucleus
Cytosol Expressed in all parathyroid gland: 130.0 -NME8 CILD6, NM23-H8, SPTRX2, TXNDC3 ENSG00000086288 NME/NM23 family member 8 7 37848597-37900401 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB016416, HPA019259 Supported Group enriched 14 bone marrow: 8.2;testis: 18.3 spleen: 0.9 -EPDR1 EPDR, MERP-1, MERP1, UCC1 ENSG00000086289 Ependymin related 1 7 37683843-37951941 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB026298 Approved Expressed in all cerebral cortex: 73.6 -SNX10 ENSG00000086300 Sorting nexin 10 7 26291895-26374329 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015605, HPA064782 Approved Approved Nucleus
Nucleoli
Microtubules Tissue enhanced 0 cerebral cortex: 94.6 lung: 60.7 -SEPHS1 SPS, SPS1 ENSG00000086475 Selenophosphate synthetase 1 10 13317424-13348298 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037645 Uncertain Uncertain Nucleoplasm Expressed in all thyroid gland: 92.5 -MRPL28 MAAT1, p15 ENSG00000086504 Mitochondrial ribosomal protein L28 16 367384-370527 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030594, CAB033542, HPA055589 Supported Supported Mitochondria Expressed in all cerebral cortex: 71.7 -HBQ1 HBQ ENSG00000086506 Hemoglobin, theta 1 16 180453-181181 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062473 Supported Approved Lipid droplets Group enriched 8 bone marrow: 14.7;cerebral cortex: 3.0 placenta: 1.1 -ITPKC IP3-3KC, IP3KC ENSG00000086544 Inositol-trisphosphate 3-kinase C 19 40717103-40740860 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050760, HPA053003 Approved Supported Nuclear speckles Expressed in all esophagus: 69.5 -CEACAM6 CD66c, NCA ENSG00000086548 Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 19 41750977-41772208 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008370, HPA011041 Supported Group enriched 6 bone marrow: 110.9;colon: 184.1;esophagus: 174.2;gallbladder: 190.2;lung: 406.1;rectum: 236.9 appendix: 38.9 -FAT2 CDHF8, CDHR9, HFAT2, MEGF1 ENSG00000086570 FAT atypical cadherin 2 5 151504093-151568944 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033680 Supported Tissue enhanced 0 skin: 66.6 esophagus: 14.4 -RBM22 Cwc2, FLJ10290, fSAP47, ZC3H16 ENSG00000086589 RNA binding motif protein 22 5 150690794-150701107 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001634 Supported Validated Nucleus Expressed in all bone marrow: 40.3 -TMED2 P24A, p24b1, p24beta1, RNP24 ENSG00000086598 Transmembrane p24 trafficking protein 2 12 123584531-123598577 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014060 Approved Supported Vesicles Expressed in all thyroid gland: 327.0 -ERO1B ERO1-L(beta), Ero1beta, ERO1LB ENSG00000086619 Endoplasmic reticulum oxidoreductase beta 1 236215555-236281985 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028085 Approved Expressed in all testis: 51.2 -ZFAND6 AWP1, ZA20D3, ZFAND5B ENSG00000086666 Zinc finger, AN1-type domain 6 15 80059568-80138393 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034845 Uncertain Expressed in all testis: 246.4 -HSD17B2 HSD17, SDR9C2 ENSG00000086696 Hydroxysteroid (17-beta) dehydrogenase 2 16 82035004-82098534 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021826, HPA050235 Supported Approved Endoplasmic reticulum Tissue enhanced 0 duodenum: 443.2;placenta: 548.0 small intestine: 204.1 -TXLNG CXorf15, FIAT, FLJ11209, LSR5, MGC126621, MGC126625, TXLNGX ENSG00000086712 Taxilin gamma X 16786427-16844519 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000297, HPA000841 Approved Approved Cytosol Expressed in all adrenal gland: 20.9 -PPEF1 PPEF, PPP7CA ENSG00000086717 Protein phosphatase, EF-hand calcium binding domain 1 X 18675909-18827921 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034577 Uncertain Uncertain Plasma membrane
Cytokinetic bridge Tissue enriched 7 testis: 26.2 cerebral cortex: 3.6 -LAT2 HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5 ENSG00000086730 Linker for activation of T cells family, member 2 7 74199652-74229834 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003462 Supported Tissue enhanced 0 lymph node: 71.0 tonsil: 61.3 -HUWE1 Ib772, KIAA0312, UREB1 ENSG00000086758 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase X 53532096-53686729 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002548, CAB022718 Approved Validated Nucleoplasm
Cytosol Expressed in all parathyroid gland: 94.8 -ZW10 KNTC1AP ENSG00000086827 Zw10 kinetochore protein 11 113733187-113773811 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011565, HPA051253, HPA055410 Supported Supported Cytosol Expressed in all testis: 23.3 -ALG9 DIBD1 ENSG00000086848 ALG9, alpha-1,2-mannosyltransferase 11 111782195-111871581 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038575 Approved Approved Endoplasmic reticulum Expressed in all testis: 25.3 -MYBPC2 MGC163408, MYBPC, MYBPCF ENSG00000086967 Myosin binding protein C, fast type 19 50432903-50466321 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042991, HPA046745 Supported Group enriched 151 parathyroid gland: 921.2;skeletal muscle: 1496.2 prostate: 8.0 -NOX4 KOX, KOX-1 ENSG00000086991 NADPH oxidase 4 11 89324356-89498187 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA015475 Uncertain Approved Nucleus Tissue enriched 12 kidney: 133.6 parathyroid gland: 10.7 -ACOX3 ENSG00000087008 Acyl-CoA oxidase 3, pristanoyl 4 8366282-8440723 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035840, HPA035841 Uncertain Approved Peroxisomes Expressed in all esophagus: 22.3 -MTMR2 CMT4B, KIAA1073 ENSG00000087053 Myotubularin related protein 2 11 95832882-95925315 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049831 Approved Supported Vesicles Expressed in all testis: 57.6 -PPP1R15A GADD34 ENSG00000087074 Protein phosphatase 1, regulatory subunit 15A 19 48872392-48876057 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB018395, HPA020240 Approved Uncertain Vesicles Expressed in all bone marrow: 358.8 -HSD17B14 DHRS10, retSDR3, SDR47C1 ENSG00000087076 Hydroxysteroid (17-beta) dehydrogenase 14 19 48813017-48836678 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021467 Approved Mixed kidney: 53.1 -TRIP6 MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1 ENSG00000087077 Thyroid hormone receptor interactor 6 7 100867138-100873454 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046454, CAB046460, HPA052813 Approved Supported Plasma membrane
Focal adhesion sites
Cytosol Expressed in all parathyroid gland: 84.3 -ACHE YT ENSG00000087085 Acetylcholinesterase (Yt blood group) 7 100889994-100896974 Blood group antigen proteins, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019704, HPA027098 Approved Golgi apparatus
Vesicles Tissue enhanced 0 skeletal muscle: 58.5 cerebral cortex: 14.1 -FTL MGC71996, NBIA3 ENSG00000087086 Ferritin, light polypeptide 19 48965301-48966878 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020769, HPA041602 Supported Approved Cytosol Expressed in all lung: 8051.2 -SRRT ARS2, Asr2, serrate ENSG00000087087 Serrate, RNA effector molecule 7 100875111-100888664 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042858, HPA058379 Supported Validated Nucleoplasm Expressed in all testis: 203.7 -BAX BCL2L4 ENSG00000087088 BCL2-associated X protein 19 48954815-48961798 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004206, HPA027878 Approved Expressed in all appendix: 83.2 -NLK ENSG00000087095 Nemo-like kinase 17 28041737-28196381 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018192, HPA056511 Approved Supported Nucleus
Nucleoli
Cell Junctions Expressed in all cerebral cortex: 52.5 -PIGS ENSG00000087111 Phosphatidylinositol glycan anchor biosynthesis, class S 17 28553383-28571872 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018149 Approved Mixed thyroid gland: 13.5 -ADAMTS2 ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP ENSG00000087116 ADAM metallopeptidase with thrombospondin type 1 motif, 2 5 179110851-179345430 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA028444 Uncertain Approved Vesicles
Plasma membrane Mixed placenta: 27.2 -TMPRSS11E DESC1, TMPRSS11E2 ENSG00000087128 Transmembrane protease, serine 11E 4 68447449-68497604 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051062 Uncertain Tissue enriched 5 esophagus: 128.6 epididymis: 24.6 -ATXN7L3 DKFZp761G2113 ENSG00000087152 Ataxin 7-like 3 17 44191805-44200113 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064316 Supported Approved Nuclear speckles
Plasma membrane Expressed in all cerebral cortex: 84.0 -PGS1 DKFZP762M186 ENSG00000087157 Phosphatidylglycerophosphate synthase 1 17 78378640-78425114 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA022526 Approved Approved Vesicles
Cell Junctions
Intermediate filaments Expressed in all placenta: 26.5 -PSMC5 p45, p45/SUG, S8, SUG-1, SUG1, TBP10, TRIP1 ENSG00000087191 Proteasome 26S subunit, ATPase 5 17 63827152-63832026 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017871, HPA064293 Uncertain Supported Plasma membrane
Cytosol Expressed in all parathyroid gland: 245.8 -UIMC1 RAP80 ENSG00000087206 Ubiquitin interaction motif containing 1 5 176905005-177022633 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037503, HPA037504 Approved Validated Nuclear bodies Expressed in all testis: 109.1 -CETP BPIFF ENSG00000087237 Cholesteryl ester transfer protein, plasma 16 56961850-56983845 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 adipose tissue: 36.8;liver: 21.6;lymph node: 47.1;placenta: 50.0;spleen: 79.2 thyroid gland: 8.4 -MMP2 CLG4, CLG4A, TBE-1 ENSG00000087245 Matrix metallopeptidase 2 16 55389700-55506691 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001939, CAB002788 Approved Uncertain Vesicles
Cytosol Tissue enhanced 0 gallbladder: 1688.5 urinary bladder: 944.6 -MT3 GIF ENSG00000087250 Metallothionein 3 16 56589074-56591088 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004011, CAB017779 Supported Tissue enriched 17 cerebral cortex: 740.5 adrenal gland: 43.0 -LPCAT2 AGPAT11, AYTL1, FLJ20481, LysoPAFAT ENSG00000087253 Lysophosphatidylcholine acyltransferase 2 16 55508998-55586670 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007891, HPA008433 Supported Supported Validated Endoplasmic reticulum
Lipid droplets Tissue enhanced 0 thyroid gland: 141.9 bone marrow: 56.6 -GNAO1 G-ALPHA-o ENSG00000087258 Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 16 56191390-56357444 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008387, HPA040878 Supported Tissue enriched 9 cerebral cortex: 324.2 seminal vesicle: 36.8 -OGFOD1 FLJ10826, KIAA1612, TPA1 ENSG00000087263 2-oxoglutarate and iron-dependent oxygenase domain containing 1 16 56451490-56479100 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003215 Approved Approved Supported Nucleus
Cytosol Expressed in all smooth muscle: 21.5 -SH3BP2 CRBM, RES4-23 ENSG00000087266 SH3-domain binding protein 2 4 2793023-2841098 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036790 Approved Approved Nucleus
Actin filaments Expressed in all spleen: 62.0 -NOP14 C4orf9, NOL14, RES4-25, UTP2 ENSG00000087269 NOP14 nucleolar protein 4 2937933-2963385 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039596, HPA055652 Approved Validated Nucleus
Nucleoli Expressed in all lymph node: 27.6 -ADD1 ENSG00000087274 Adducin 1 (alpha) 4 2843857-2930076 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009794, HPA035873, HPA035874 Supported Validated Nucleoplasm
Plasma membrane Expressed in all cerebral cortex: 201.7 -L2HGDH C14orf160, FLJ12618 ENSG00000087299 L-2-hydroxyglutarate dehydrogenase 14 50237563-50312548 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065409, HPA069708 Approved Validated Mitochondria Mixed kidney: 20.7 -TXNDC16 KIAA1344 ENSG00000087301 Thioredoxin domain containing 16 14 52430590-52552522 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA002543 Approved Approved Mitochondria Tissue enhanced 0 prostate: 41.9 seminal vesicle: 18.2 -C14orf166 CGI-99, CLE, CLE7, LCRP369, RLLM1 ENSG00000087302 Chromosome 14 open reading frame 166 14 51989475-52010691 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039824 Supported Supported Nucleoplasm Expressed in all testis: 261.5 -NID2 ENSG00000087303 Nidogen 2 (osteonidogen) 14 52004803-52069228 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052460, HPA058772 Supported Supported Plasma membrane Tissue enhanced 0 placenta: 87.4 thyroid gland: 53.5 -GMCL1 BTBD13, FLJ13057, GCL1, SPATA29 ENSG00000087338 Germ cell-less, spermatogenesis associated 1 2 69829642-69881396 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039579 Approved Expressed in all testis: 39.2 -SF3B2 Cus1, SAP145, SF3b1, SF3b145 ENSG00000087365 Splicing factor 3b, subunit 2, 145kDa 11 66050729-66069308 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045028 Supported Validated Nuclear speckles Expressed in all testis: 192.8 -KLHL42 Ctb9, KIAA1340, KLHDC5 ENSG00000087448 Kelch-like family member 42 12 27780020-27803040 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020979 Uncertain Mixed smooth muscle: 32.5 -GNAS GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI ENSG00000087460 GNAS complex locus 20 58839718-58911192 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010337, HPA018122, HPA027478, HPA028386 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all thyroid gland: 1471.9 -DNM1L DRP1, DVLP, DYMPLE, HDYNIV, VPS1 ENSG00000087470 Dynamin 1-like 12 32679200-32745650 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009952, HPA039324 Supported Validated Vesicles
Cytosol Expressed in all cerebral cortex: 88.3 -PTHLH HHM, PLP, PTHR, PTHRP ENSG00000087494 Parathyroid hormone-like hormone 12 27958084-27972705 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035982 Approved Approved Supported Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced 0 breast: 23.9 esophagus: 18.1 -PHACTR3 C20orf101, PPP1R123 ENSG00000087495 Phosphatase and actin regulator 3 20 59577509-59847711 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051834, HPA054847 Validated Nucleoplasm Tissue enriched 9 cerebral cortex: 65.0 spleen: 7.5 -ERGIC2 Erv41, PTX1 ENSG00000087502 ERGIC and golgi 2 12 29337352-29381189 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049695 Approved Supported Nucleoli
Vesicles Expressed in all testis: 105.6 -TFAP2C AP2-GAMMA, ERF1, hAP-2g, TFAP2G ENSG00000087510 Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 20 56629302-56639283 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016061, CAB016079, HPA055179, HPA057076 Supported Supported Nucleoplasm Tissue enhanced 0 skin: 63.1 breast: 31.6 -AURKA AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7 ENSG00000087586 Aurora kinase A 20 56369389-56392337 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001454, HPA002636 Approved Approved Nucleus
Centrosome
Cytosol Tissue enhanced 0 testis: 53.3 lymph node: 24.3 -CASS4 C20orf32, HEFL, HEPL ENSG00000087589 Cas scaffolding protein family member 4 20 56412112-56460387 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034217 Approved Tissue enhanced 0 appendix: 18.2;lung: 23.9 spleen: 10.9 -PIR ENSG00000087842 Pirin (iron-binding nuclear protein) X 15384799-15493564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000697 Approved Supported Cytosol Mixed urinary bladder: 23.4 -AAMDC C11orf67, CK067, FLJ21035, PTD015 ENSG00000087884 Adipogenesis associated, Mth938 domain containing 11 77821109-77918432 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037918, HPA037919 Approved Approved Nucleoplasm
Cytosol Expressed in all skeletal muscle: 231.8 -RFX2 FLJ14226 ENSG00000087903 Regulatory factor X, 2 (influences HLA class II expression) 19 5993164-6199572 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048969 Supported Approved Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced 0 testis: 93.2 fallopian tube: 32.5 -METTL2A FLJ12760, METTL2 ENSG00000087995 Methyltransferase like 2A 17 62423867-62450822 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 9.0 -SULT2B1 HSST2 ENSG00000088002 Sulfotransferase family, cytosolic, 2B, member 1 19 48552075-48599425 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033013, HPA041724, HPA043539 Approved Supported Vesicles
Cytosol Tissue enhanced 0 esophagus: 152.8;skin: 152.7 cervix: 45.7 -ALG6 ENSG00000088035 ALG6, alpha-1,3-glucosyltransferase 1 63367590-63438562 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062536 Supported Endoplasmic reticulum Mixed placenta: 11.8 -CNOT3 KIAA0691, LENG2, NOT3, NOT3H ENSG00000088038 CCR4-NOT transcription complex, subunit 3 19 54137728-54155681 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006408 Approved Approved Cytosol Expressed in all testis: 36.1 -GP6 GPVI ENSG00000088053 Glycoprotein VI (platelet) 19 55013705-55038264 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA066482 Approved Approved Nucleoplasm Tissue enhanced 0 testis: 1.3 skin: 0.7 -PTPN4 PTPMEG ENSG00000088179 Protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2 119759631-119983818 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019351 Uncertain Approved Nucleus
Plasma membrane
Cytosol Mixed thyroid gland: 24.4 -DDX18 MrDb ENSG00000088205 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 2 117814650-117832379 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035400, HPA041056 Approved Validated Nucleoli Expressed in all thyroid gland: 49.4 -KHSRP FBP2, FUBP2, KSRP ENSG00000088247 KH-type splicing regulatory protein 19 6413348-6424794 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034739, HPA056518 Supported Validated Nucleoplasm Expressed in all testis: 179.2 -GNA11 FBH, FBH2, FHH2, HHC2 ENSG00000088256 Guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 19 3094410-3124004 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048886 Approved Expressed in all small intestine: 159.0 -ASAP3 CENTB6, DDEFL1, FLJ20199, UPLC1 ENSG00000088280 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1 23428563-23484568 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020537, HPA020546 Approved Supported Nucleoplasm
Vesicles Mixed skin: 32.6 -EDEM2 bA4204.1, C20orf31, C20orf49, FLJ10783 ENSG00000088298 ER degradation enhancer, mannosidase alpha-like 2 20 35115357-35147364 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037238, HPA048353 Approved Expressed in all epididymis: 53.8 -DNMT3B ENSG00000088305 DNA (cytosine-5-)-methyltransferase 3 beta 20 32762385-32809356 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001595, CAB069896 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 testis: 9.2 skin: 4.5 -REM1 GES, REM ENSG00000088320 RAS (RAD and GEM)-like GTP-binding 1 20 31475293-31484905 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049821 Approved Mixed cervix: 12.3 -TPX2 C20orf1, C20orf2, DIL-2, p100 ENSG00000088325 TPX2, microtubule-associated 20 31739271-31801805 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005487 Uncertain Supported Nucleoplasm
Mitotic spindle Tissue enhanced 0 testis: 55.4 lymph node: 31.8 -PDRG1 C20orf126, dJ310O13.3 ENSG00000088356 P53 and DNA-damage regulated 1 20 31944342-31952092 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047084, HPA063542 Approved Approved Actin filaments Expressed in all parathyroid gland: 63.6 -EPB41L1 4.1N, KIAA0338 ENSG00000088367 Erythrocyte membrane protein band 4.1-like 1 20 36091504-36232799 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054104, HPA056817 Approved Supported Plasma membrane Mixed adrenal gland: 163.2 -SLC15A1 HPECT1, HPEPT1, PEPT1 ENSG00000088386 Solute carrier family 15 (oligopeptide transporter), member 1 13 98683801-98752654 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA002827 Uncertain Approved Nucleoplasm
Cytosol Group enriched 5 duodenum: 157.7;gallbladder: 68.0;small intestine: 230.1 skin: 27.9 -DOCK9 KIAA1058, ZIZ1 ENSG00000088387 Dedicator of cytokinesis 9 13 98793487-99086625 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034061, CAB034065, HPA043940 Uncertain Expressed in all placenta: 157.4 -ANKRD10 FLJ20093 ENSG00000088448 Ankyrin repeat domain 10 13 110878540-110915069 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034211, HPA038878, HPA038879 Uncertain Approved Microtubules
Cytosol Expressed in all epididymis: 107.8 -TGDS SDR2E1, TDPGD ENSG00000088451 TDP-glucose 4,6-dehydratase 13 94574051-94596257 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039927, HPA040857 Approved Approved Nucleus
Nucleoli
Intermediate filaments Expressed in all thyroid gland: 21.6 -DOCK3 KIAA0299, MOCA, PBP ENSG00000088538 Dedicator of cytokinesis 3 3 50675241-51384198 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037543, HPA037544 Approved Validated Cytosol Group enriched 6 cerebral cortex: 33.8;parathyroid gland: 12.5;testis: 8.5;thyroid gland: 15.1 adrenal gland: 3.0 -C3orf18 G20 ENSG00000088543 Chromosome 3 open reading frame 18 3 50558025-50571027 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA012105 Approved Approved Cytosol Mixed parathyroid gland: 27.8 -COQ9 C16orf49, DKFZP434K046 ENSG00000088682 Coenzyme Q9 16 57447425-57461275 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040918 Supported Approved Cytosol Expressed in all parathyroid gland: 89.0 -TMEM40 FLJ11036 ENSG00000088726 Transmembrane protein 40 3 12733525-12769457 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044165 Supported Approved Cytosol Group enriched 8 esophagus: 89.2;placenta: 23.2;skin: 55.5;tonsil: 24.8 urinary bladder: 6.4 -KIF9 MGC104186 ENSG00000088727 Kinesin family member 9 3 47228026-47283451 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022031, HPA022033, HPA030429 Approved Approved Nucleus
Nucleoli Expressed in all testis: 87.0 -ARHGAP28 FLJ10312, KIAA1314 ENSG00000088756 Rho GTPase activating protein 28 18 6729718-6915716 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030413, HPA030414, HPA030415 Supported Supported Cell Junctions Tissue enhanced 0 testis: 132.2 placenta: 40.5 -CRLS1 C20orf155, CLS1, dJ967N21.6, GCD10 ENSG00000088766 Cardiolipin synthase 1 20 6006090-6040053 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all liver: 86.7 -DEFB127 bA530N10.2, C20orf73, DEF-27 ENSG00000088782 Defensin, beta 127 20 157470-159163 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 1012 epididymis: 1377.6 seminal vesicle: 1.3 -PPP1R13B ASPP1, KIAA0771, p53BP2-like, p85 ENSG00000088808 Protein phosphatase 1, regulatory subunit 13B 14 103733752-103847590 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006394, CAB015454 Approved Supported Nucleoplasm
Cytosol Mixed thyroid gland: 43.8 -ATRN DPPT-L, MGCA ENSG00000088812 Attractin 20 3471040-3651122 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008853 Uncertain Approved Cytosol Expressed in all parathyroid gland: 83.4 -SMOX C20orf16, dJ779E11.1, FLJ20746, MGC1010, PAO, PAOh1, SMO ENSG00000088826 Spermine oxidase 20 4120980-4187747 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047117, HPA060198 Approved Supported Nucleoplasm
Nuclear membrane
Vesicles Tissue enhanced 0 cerebral cortex: 49.8 gallbladder: 23.5 -SIGLEC1 CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN ENSG00000088827 Sialic acid binding Ig-like lectin 1, sialoadhesin 20 3686970-3707128 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053457 Supported Mixed placenta: 27.1 -FKBP1A FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE ENSG00000088832 FK506 binding protein 1A, 12kDa 20 1368978-1393172 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004639, HPA051798, HPA057830 Uncertain Approved Microtubules Expressed in all thyroid gland: 368.4 -NSFL1C dJ776F14.1, p47, UBX1, UBXD10, UBXN2C ENSG00000088833 NSFL1 (p97) cofactor (p47) 20 1442162-1473842 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047108, HPA050628 Supported Validated Nucleoplasm
Plasma membrane
Cytosol Expressed in all cerebral cortex: 35.2 -SLC4A11 BTR1, CDPD1, CHED2, dJ794I6.2, FECD4, NaBC1 ENSG00000088836 Solute carrier family 4, sodium borate transporter, member 11 20 3227417-3239190 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018120, HPA058377 Uncertain Uncertain Nucleoplasm
Vesicles Tissue enhanced 0 salivary gland: 19.3;thyroid gland: 27.6 cervix: 14.3 -C20orf194 DKFZp434N061 ENSG00000088854 Chromosome 20 open reading frame 194 20 3249305-3407625 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052103, HPA067418 Approved Approved Nucleoli fibrillar center
Mitochondria
Cytosol Expressed in all cerebral cortex: 26.5 -ZNF343 MGC10715 ENSG00000088876 Zinc finger protein 343 20 2481817-2524702 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA030587, HPA052438 Approved Approved Nucleoplasm Mixed parathyroid gland: 15.7 -EBF4 COE4, KIAA1442, O/E-4, RP5-860F19.3 ENSG00000088881 Early B-cell factor 4 20 2692878-2760108 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed parathyroid gland: 23.4 -CPXM1 CPX-1, CPX1, CPXM ENSG00000088882 Carboxypeptidase X (M14 family), member 1 20 2794069-2800637 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 endometrium: 130.2;gallbladder: 132.9 urinary bladder: 77.4 -MAVS Cardif, IPS-1, KIAA1271, VISA ENSG00000088888 Mitochondrial antiviral signaling protein 20 3846799-3876123 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009187, HPA049850, HPA053524 Supported Validated Mitochondria Expressed in all parathyroid gland: 30.4 -RP5-1187M17.10 ENSG00000088899 Leucine zipper putative tumor suppressor 3 20 3162617-3173592 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031008, HPA031009 Approved Tissue enhanced 0 cerebral cortex: 58.7 parathyroid gland: 19.9 -F11 FXI ENSG00000088926 Coagulation factor XI 4 186265945-186288806 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039808 Approved Vesicles Tissue enhanced 0 liver: 179.3 kidney: 44.4 -XRN2 ENSG00000088930 5'-3' exoribonuclease 2 20 21303304-21389827 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047118, HPA050485 Supported Validated Nucleus
Nucleoli Expressed in all parathyroid gland: 73.7 -KIZ C20orf19, HT013, NCRNA00153, PLK1S1 ENSG00000088970 Kizuna centrosomal protein 20 21125983-21246622 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all testis: 81.9 -DYNLL1 DLC1, DLC8, DNCL1, hdlc1, LC8, PIN ENSG00000088986 Dynein, light chain, LC8-type 1 12 120469850-120498493 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039954 Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all fallopian tube: 769.1 -TESC CHP3, FLJ20607, TSC ENSG00000088992 Tescalcin 12 117038923-117099479 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053200 Approved Supported Nucleus
Cytosol Tissue enhanced 0 epididymis: 133.5;salivary gland: 132.2;stomach: 120.5 bone marrow: 67.1 -SNX5 ENSG00000089006 Sorting nexin 5 20 17941597-17968980 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020679, HPA051187 Approved Approved Nucleoli
Cytosol Expressed in all thyroid gland: 132.0 -RPL6 L6, TAXREB107, TXREB1 ENSG00000089009 Ribosomal protein L6 12 112405190-112418838 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068418 Approved Expressed in all ovary: 3211.7 -SIRPG bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma ENSG00000089012 Signal-regulatory protein gamma 20 1629152-1657779 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lymph node: 39.4;tonsil: 26.8 appendix: 17.6 -MAPKAPK5 PRAK ENSG00000089022 Mitogen-activated protein kinase-activated protein kinase 5 12 111841978-111902238 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004546, HPA015515 Supported Supported Nucleoplasm
Cytosol Expressed in all rectum: 34.4 -P2RX7 MGC20089, P2X7 ENSG00000089041 Purinergic receptor P2X, ligand gated ion channel, 7 12 121132819-121188032 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034968, HPA042013, HPA044141 Approved Mixed cerebral cortex: 21.1 -ESF1 bA526K24.1, C20orf6 ENSG00000089048 ESF1 nucleolar pre-rRNA processing protein homolog 20 13714322-13784886 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047083, HPA050396 Supported Approved Nucleus
Nucleoli Expressed in all testis: 25.8 -RBBP9 Bog ENSG00000089050 Retinoblastoma binding protein 9 20 18486540-18497243 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015830, HPA049005 Approved Supported Nucleoplasm Expressed in all thyroid gland: 40.6 -ANAPC5 APC5 ENSG00000089053 Anaphase promoting complex subunit 5 12 121308245-121399896 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039457, HPA039801 Supported Approved Nucleoplasm Expressed in all fallopian tube: 87.8 -SLC23A2 KIAA0238, SLC23A1, SVCT2, YSPL2 ENSG00000089057 Solute carrier family 23 (ascorbic acid transporter), member 2 20 4852356-5010293 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052825, HPA059314 Approved Supported Golgi apparatus
Vesicles Expressed in all adrenal gland: 98.6 -SLC8B1 FLJ22233, NCKX6, NCLX, SLC24A6 ENSG00000089060 Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 12 113298759-113359493 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA040668 Approved Expressed in all adrenal gland: 48.6 -TMEM230 C20orf30, HSPC274 ENSG00000089063 Transmembrane protein 230 20 5068232-5113103 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009078, HPA061421 Uncertain Validated Endoplasmic reticulum Expressed in all thyroid gland: 226.3 -DZANK1 ANKRD64, bA189K21.8, C20orf12, C20orf84, dJ568F9.2, FLJ10600, FLJ30892 ENSG00000089091 Double zinc ribbon and ankyrin repeat domains 1 20 18383367-18467281 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA059478, HPA064255 Uncertain Approved Nucleoli fibrillar center Mixed fallopian tube: 5.2 -KDM2B CXXC2, Fbl10, FBXL10, JHDM1B, PCCX2 ENSG00000089094 Lysine (K)-specific demethylase 2B 12 121429097-121581015 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071257 Uncertain Nucleoplasm Expressed in all lymph node: 36.3 -CFAP61 C20orf26, CaM-IP3, dJ1002M8.3, DKFZP434K156 ENSG00000089101 Cilia and flagella associated protein 61 20 20052514-20360702 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA009079 Uncertain Group enriched 6 fallopian tube: 20.0;heart muscle: 6.9;testis: 30.1 skeletal muscle: 3.3 -LHX5 ENSG00000089116 LIM homeobox 5 12 113462034-113472280 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053908 Uncertain Tissue enhanced 0 cerebral cortex: 1.4 stomach: 0.3 -TASP1 C20orf13, dJ585I14.2, FLJ20212 ENSG00000089123 Taspase, threonine aspartase, 1 20 13389392-13638940 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030824, HPA030825 Uncertain Approved Plasma membrane Mixed parathyroid gland: 13.5 -OAS1 IFI-4, OIAS, OIASI ENSG00000089127 2'-5'-oligoadenylate synthetase 1, 40/46kDa 12 112906777-112933222 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003657, CAB021104 Uncertain Approved Cytosol Expressed in all spleen: 91.9 -GCN1 GCN1L, GCN1L1, KIAA0219 ENSG00000089154 GCN1 eIF2 alpha kinase activator homolog 12 120127203-120194710 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018799, HPA019648, HPA024367 Supported Validated Cytosol Expressed in all parathyroid gland: 36.8 -RPLP0 L10E, LP0, P0, PRLP0, RPP0 ENSG00000089157 Ribosomal protein, large, P0 12 120196686-120201235 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003512 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all breast: 2849.3 -PXN ENSG00000089159 Paxillin 12 120210439-120265771 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003841, HPA051309 Supported Validated Focal adhesion sites
Cytosol Expressed in all placenta: 112.3 -SIRT4 SIR2L4 ENSG00000089163 Sirtuin 4 12 120302316-120313249 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029691, HPA029692 Approved Mixed testis: 9.5 -RPH3A exophilin-1, KIAA0985, rabphilin ENSG00000089169 Rabphilin 3A 12 112570380-112898881 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002475 Supported Tissue enriched 7 cerebral cortex: 95.5 bone marrow: 13.9 -KIF16B C20orf23, dJ971B4.1, FLJ20135, SNX23 ENSG00000089177 Kinesin family member 16B 20 16272104-16573433 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051198 Approved Uncertain Mitochondria Expressed in all parathyroid gland: 43.3 -TRMT6 CGI-09, GCD10, Gcd10p, MGC5029 ENSG00000089195 TRNA methyltransferase 6 20 5937235-5950558 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047032, HPA050408 Approved Supported Nucleus Expressed in all testis: 25.3 -CHGB SCG1, SgI ENSG00000089199 Chromogranin B 20 5911430-5925361 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008759, CAB009403, HPA012602 Supported Supported Supported Vesicles Tissue enriched 26 adrenal gland: 4403.0 cerebral cortex: 168.7 -PEBP1 HCNP, PBP, PEBP, RKIP ENSG00000089220 Phosphatidylethanolamine binding protein 1 12 118135858-118145584 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008819, CAB009906, CAB013493 Supported Approved Plasma membrane
Cytosol Expressed in all adrenal gland: 1649.3 -TBX5 HOS ENSG00000089225 T-box 5 12 114353931-114408442 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA008786, HPA064683 Uncertain Approved Nucleoplasm Group enriched 7 heart muscle: 47.1;lung: 18.0;placenta: 46.6 prostate: 5.2 -BRAP BRAP2, IMP, RNF52 ENSG00000089234 BRCA1 associated protein 12 111642146-111685986 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040357, HPA058820 Approved Supported Nuclear membrane
Cytosol Tissue enriched 6 testis: 120.2 bone marrow: 21.2 -ERP29 C12orf8, ERp28, ERp29, ERp31, PDI-DB, PDIA9 ENSG00000089248 Endoplasmic reticulum protein 29 12 112013316-112023451 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039363, HPA039456 Supported Uncertain Nucleoplasm
Microtubules Expressed in all parathyroid gland: 149.3 -NOS1 nNOS, NOS ENSG00000089250 Nitric oxide synthase 1 (neuronal) 12 117208142-117452170 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002167, HPA058312 Uncertain Supported Nucleoplasm
Plasma membrane Tissue enhanced 0 skeletal muscle: 12.9 cerebral cortex: 3.0 -FUS ALS6, FUS1, hnRNP-P2, HNRNPP2, TLS ENSG00000089280 FUS RNA binding protein 16 31180110-31194871 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008784, CAB033036, CAB058691 Supported Validated Nucleoplasm Expressed in all cerebral cortex: 146.2 -IGBP1 IBP1 ENSG00000089289 Immunoglobulin (CD79A) binding protein 1 X 70133449-70166324 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000634, HPA001004, CAB034139 Approved Approved Microtubules
Cytosol Expressed in all ovary: 146.8 -FXYD5 OIT2 ENSG00000089327 FXYD domain containing ion transport regulator 5 19 35154730-35169883 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010817 Uncertain Approved Endoplasmic reticulum Expressed in all spleen: 241.4 -ZNF302 ZNF135L, ZNF140L, ZNF327 ENSG00000089335 Zinc finger protein 302 19 34677639-34686397 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA059503 Approved Vesicles
Cytokinetic bridge Expressed in all parathyroid gland: 41.4 -GRAMD1A FLJ90346, KIAA1533 ENSG00000089351 GRAM domain containing 1A 19 34994784-35026471 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008852, HPA012570 Approved Approved Plasma membrane
Cytosol Expressed in all appendix: 36.8 -FXYD3 MAT-8, PLML ENSG00000089356 FXYD domain containing ion transport regulator 3 19 35115879-35124324 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA010856 Supported Supported Plasma membrane Tissue enhanced 0 colon: 1480.8;rectum: 1982.1 prostate: 686.5 -HEPH CPL, KIAA0698 ENSG00000089472 Hephaestin X 66162549-66268867 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA005824 Approved Mixed smooth muscle: 117.4 -CDIP1 C16orf5, CDIP, LITAFL ENSG00000089486 Cell death-inducing p53 target 1 16 4510675-4538828 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049352 Approved Supported Nucleoplasm
Centrosome Expressed in all cerebral cortex: 73.2 -CMTM1 CKLFH, CKLFH1a, CKLFSF1 ENSG00000089505 CKLF-like MARVEL transmembrane domain containing 1 16 66566393-66579137 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA013801, HPA017136 Uncertain Approved Nucleoplasm Tissue enriched 6 testis: 28.8 spleen: 4.5 -KCNH4 elk1, Kv12.3 ENSG00000089558 Potassium channel, voltage gated eag related subfamily H, member 4 17 42156891-42181278 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 1.8 appendix: 0.7 -GANAB G2AN, GluII, KIAA0088 ENSG00000089597 Glucosidase, alpha; neutral AB 11 62624826-62646726 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026874, HPA061426 Supported Approved Nuclear membrane
Endoplasmic reticulum
Cytosol Expressed in all parathyroid gland: 289.5 -GMIP ARHGAP46 ENSG00000089639 GEM interacting protein 19 19629476-19643667 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042484, HPA045481 Approved Validated Nucleoplasm
Plasma membrane
Cytosol Mixed spleen: 47.6 -RBM41 FLJ11016 ENSG00000089682 RNA binding motif protein 41 X 107064420-107118823 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042881 Approved Approved Nuclear speckles
Cytosol Mixed parathyroid gland: 18.9 -BIRC5 API4, EPR-1, survivin ENSG00000089685 Baculoviral IAP repeat containing 5 17 78214186-78225636 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002830, CAB004270 Supported Validated Cytokinetic bridge Tissue enhanced 0 testis: 26.7 bone marrow: 22.7 -LAG3 CD223 ENSG00000089692 Lymphocyte-activation gene 3 12 6772512-6778455 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB002301, HPA013967 Supported Tissue enhanced 0 spleen: 32.6 lymph node: 17.8 -MLF2 NTN4 ENSG00000089693 Myeloid leukemia factor 2 12 6747996-6767475 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010811, HPA010859 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all cerebral cortex: 273.3 -OTUB2 C14orf137, FLJ21916, MGC3102 ENSG00000089723 OTU deubiquitinase, ubiquitin aldehyde binding 2 14 94026329-94048930 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002329, HPA075090 Supported Approved Nucleoplasm Tissue enhanced 0 testis: 9.8 skin: 4.7 -DDX24 ENSG00000089737 DEAD (Asp-Glu-Ala-Asp) box helicase 24 14 94048291-94081245 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002554 Uncertain Approved Nucleoli
Cytosol Tissue enhanced 0 epididymis: 44.5 adrenal gland: 13.3 -ZBTB25 C14orf51, KUP, ZNF46 ENSG00000089775 Zinc finger and BTB domain containing 25 14 64449106-64505213 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054699 Uncertain Validated Nucleoplasm Mixed thyroid gland: 14.7 -NECAP1 DKFZP566B183 ENSG00000089818 NECAP endocytosis associated 1 12 8082211-8097771 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053980, HPA063300 Uncertain Approved Vesicles
Cytosol Expressed in all cerebral cortex: 115.2 -ARHGAP4 C1, KIAA0131, p115, RhoGAP4, SrGAP4 ENSG00000089820 Rho GTPase activating protein 4 X 153907367-153934999 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001012, HPA001083 Supported Approved Nucleoplasm
Focal adhesion sites Tissue enhanced 0 spleen: 96.8 lymph node: 88.6 -ANKRD24 KIAA1981 ENSG00000089847 Ankyrin repeat domain 24 19 4183354-4224814 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041534, HPA048498 Uncertain Uncertain Microtubules
Cytosol Tissue enhanced 0 cerebral cortex: 13.6;testis: 7.0 prostate: 2.8 -DHX32 DDX32, DHLP1, FLJ10694, FLJ10889 ENSG00000089876 DEAH (Asp-Glu-Ala-His) box polypeptide 32 10 125836337-125896436 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048872 Approved Expressed in all testis: 59.6 -RCOR1 COREST, KIAA0071, RCOR ENSG00000089902 REST corepressor 1 14 102592661-102730576 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB001956, HPA049327, HPA054241 Supported Validated Nucleoplasm Expressed in all bone marrow: 29.7 -GPATCH2L C14orf118, FLJ10033, FLJ20689 ENSG00000089916 G patch domain containing 2-like 14 76151916-76254342 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018856 Approved Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 39.9 -LTBP4 FLJ46318, FLJ90018, LTBP-4, LTBP-4L ENSG00000090006 Latent transforming growth factor beta binding protein 4 19 40592883-40629818 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015194 Approved Expressed in all ovary: 245.0 -BLVRB FLR, SDR43U1 ENSG00000090013 Biliverdin reductase B 19 40447789-40465840 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041698, HPA041937 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all bone marrow: 339.1 -SLC9A1 APNH, NHE1, PPP1R143 ENSG00000090020 Solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1 27098815-27166981 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022371, HPA048532, HPA052891 Supported Supported Plasma membrane Expressed in all stomach: 66.4 -SPTLC1 hLCB1, HSAN1, HSN1, LCB1, SPTI ENSG00000090054 Serine palmitoyltransferase, long chain base subunit 1 9 92031999-92115384 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010860, CAB018747, HPA063907 Supported Supported Endoplasmic reticulum Expressed in all thyroid gland: 108.0 -PAPOLA PAP ENSG00000090060 Poly(A) polymerase alpha 14 96501433-96567111 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001788 Supported Validated Nucleoplasm Expressed in all testis: 166.1 -CCNK CPR4 ENSG00000090061 Cyclin K 14 99481169-99535044 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000645 Supported Nucleoplasm Expressed in all testis: 83.9 -PCBP4 LIP4, MCG10 ENSG00000090097 Poly(rC) binding protein 4 3 51957454-51974016 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA057754 Supported Cytosol Expressed in all cerebral cortex: 125.7 -RGS1 1R20, BL34, IER1, IR20 ENSG00000090104 Regulator of G-protein signaling 1 1 192575727-192580031 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed appendix: 231.3 -YPEL3 MGC10500 ENSG00000090238 Yippee-like 3 16 30092314-30096915 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030501, HPA045621 Uncertain Expressed in all cerebral cortex: 117.3 -MRPS33 CGI-139 ENSG00000090263 Mitochondrial ribosomal protein S33 7 141002610-141015228 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030425 Uncertain Expressed in all epididymis: 94.6 -NDUFB2 AGGG, CI-AGGG ENSG00000090266 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 7 140690777-140722790 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051377 Approved Expressed in all thyroid gland: 495.8 -NUDC NudC ENSG00000090273 NudC nuclear distribution protein 1 26900238-26946862 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027183, HPA028105 Supported Validated Cytosol Expressed in all fallopian tube: 149.4 -MAEA EMP, GID9 ENSG00000090316 Macrophage erythroblast attacher 4 1289851-1340147 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036886, HPA058185 Approved Validated Nucleoplasm Expressed in all cerebral cortex: 38.2 -ICAM1 BB2, CD54 ENSG00000090339 Intercellular adhesion molecule 1 19 10270835-10286615 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002126, CAB002142, HPA004877 Supported Uncertain Plasma membrane
Cytosol Expressed in all lung: 256.0 -STRN4 ZIN, zinedin ENSG00000090372 Striatin, calmodulin binding protein 4 19 46719507-46746994 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043051, HPA043527, HPA056706 Supported Approved Cytosol Expressed in all testis: 105.0 -IRAK3 IRAK-M ENSG00000090376 Interleukin-1 receptor-associated kinase 3 12 66188879-66254622 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043097 Approved Approved Vesicles Tissue enhanced 0 bone marrow: 51.1 spleen: 19.3 -LYZ ENSG00000090382 Lysozyme 12 69348341-69354234 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000055, HPA048284 Supported Expressed in all stomach: 9772.4 -SI ENSG00000090402 Sucrase-isomaltase (alpha-glucosidase) 3 164978898-165078495 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011897 Supported Group enriched 15 duodenum: 562.3;small intestine: 503.3 rectum: 34.9 -MUL1 C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218 ENSG00000090432 Mitochondrial E3 ubiquitin protein ligase 1 1 20499448-20508161 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026827 Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all parathyroid gland: 39.0 -TFAP4 AP-4, bHLHc41 ENSG00000090447 Transcription factor AP-4 (activating enhancer binding protein 4) 16 4257186-4273075 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001912 Supported Supported Nucleoplasm
Mitochondria Mixed ovary: 12.0 -PDCD7 ES18, HES18 ENSG00000090470 Programmed cell death 7 15 65117379-65133836 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049388 Approved Approved Nucleoli
Plasma membrane Expressed in all testis: 30.7 -SPG21 ACP33, BM-019, GL010, MAST ENSG00000090487 Spastic paraplegia 21 (autosomal recessive, Mast syndrome) 15 64963021-64990310 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040407, HPA040436 Approved Supported Vesicles
Cytosol Expressed in all epididymis: 179.9 -FETUB ENSG00000090512 Fetuin B 3 186635969-186653141 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035132 Supported Tissue enriched 16 liver: 123.0 esophagus: 7.6 -DNAJB11 EDJ, ERdj3, HEDJ ENSG00000090520 DnaJ (Hsp40) homolog, subfamily B, member 11 3 186567403-186597203 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010814, HPA017051 Supported Supported Endoplasmic reticulum Expressed in all thyroid gland: 111.3 -P3H2 FLJ10718, LEPREL1, MLAT4 ENSG00000090530 Prolyl 3-hydroxylase 2 3 189956728-190122437 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007890, HPA013355 Approved Mixed prostate: 68.1 -THPO MGDF, MPLLG, TPO ENSG00000090534 Thrombopoietin 3 184371935-184378144 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 liver: 8.9 testis: 3.9 -CHRD ENSG00000090539 Chordin 3 184380073-184390736 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035827 Approved Mixed endometrium: 16.8 -FLT3LG ENSG00000090554 Fms-related tyrosine kinase 3 ligand 19 49474207-49486231 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed lymph node: 28.1 -RAB11FIP3 eferin, KIAA0665, Rab11-FIP3 ENSG00000090565 RAB11 family interacting protein 3 (class II) 16 425619-523011 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028088, HPA028631, HPA030086 Approved Supported Vesicles
Cytokinetic bridge
Microtubule organizing center Expressed in all kidney: 56.8 -GNPTG C16orf27, c316G12.3, CAB56184, GNPTAG ENSG00000090581 N-acetylglucosamine-1-phosphate transferase, gamma subunit 16 1351923-1364113 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004055 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all adrenal gland: 66.6 -ZNF268 HZF3 ENSG00000090612 Zinc finger protein 268 12 133181409-133214831 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001794 Approved Approved Actin filaments
Cytosol Mixed parathyroid gland: 23.0 -GOLGA3 GCP170, golgin-160, MEA-2 ENSG00000090615 Golgin A3 12 132768909-132828858 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039809, HPA040044 Supported Supported Nucleus
Golgi apparatus Expressed in all cerebral cortex: 18.5 -PABPC4 APP-1, iPABP ENSG00000090621 Poly(A) binding protein, cytoplasmic 4 (inducible form) 1 39560816-39576790 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027301, HPA056496 Approved Validated Cytosol Expressed in all skeletal muscle: 206.3 -CD209 CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1 ENSG00000090659 CD209 molecule 19 7739994-7747564 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032436, CAB033831 Supported Tissue enhanced 0 adipose tissue: 43.4 placenta: 32.8 -CERS4 FLJ12089, LASS4, Trh1 ENSG00000090661 Ceramide synthase 4 19 8206736-8262421 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033734, HPA054729 Uncertain Approved Nucleus
Vesicles Mixed thyroid gland: 80.7 -MCOLN1 ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1 ENSG00000090674 Mucolipin 1 19 7522626-7534009 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031763, CAB032637 Uncertain Supported Plasma membrane
Cytosol Expressed in all spleen: 49.0 -USP48 FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31 ENSG00000090686 Ubiquitin specific peptidase 48 1 21678298-21783606 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030045, HPA030046 Approved Approved Supported Nucleoplasm
Mitochondria
Cytosol Expressed in all adrenal gland: 54.3 -EFNB1 CFNS, Elk-L, EPLG2, LERK2 ENSG00000090776 Ephrin-B1 X 68828997-68842147 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB031489, HPA067188 Uncertain Supported Plasma membrane Mixed adipose tissue: 37.7 -PDPR PDP3 ENSG00000090857 Pyruvate dehydrogenase phosphatase regulatory subunit 16 70113626-70162537 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048092, HPA070386 Uncertain Approved Mitochondria Expressed in all testis: 29.0 -AARS CMT2N ENSG00000090861 Alanyl-tRNA synthetase 16 70252295-70289543 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034261, HPA040870, HPA044223 Supported Validated Cytosol Expressed in all parathyroid gland: 174.6 -GLG1 CFR-1, ESL-1, MG-160 ENSG00000090863 Golgi glycoprotein 1 16 74447427-74607144 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010815 Supported Validated Golgi apparatus Expressed in all parathyroid gland: 164.3 -KIF4A FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100 ENSG00000090889 Kinesin family member 4A X 70290090-70420832 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034745, HPA034746, HPA061583 Approved Validated Nucleoplasm
Cytokinetic bridge Mixed bone marrow: 7.0 -TNRC6A CAGH26, GW182, KIAA1460, TNRC6 ENSG00000090905 Trinucleotide repeat containing 6A 16 24729695-24827632 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015305, HPA017869 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all parathyroid gland: 66.9 -PLEKHG2 ARHGEF42, CLG, FLJ00018 ENSG00000090924 Pleckstrin homology domain containing, family G (with RhoGef domain) member 2 19 39412585-39428415 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017973, HPA048054 Uncertain Approved Nucleoplasm
Cytosol Expressed in all placenta: 33.0 -DLL3 SCDO1 ENSG00000090932 Delta-like 3 (Drosophila) 19 39498895-39508481 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056533 Approved Nucleoplasm
Cytosol Tissue enriched 49 cerebral cortex: 51.5 testis: 1.0 -NAT14 KLP1 ENSG00000090971 N-acetyltransferase 14 (GCN5-related, putative) 19 55485004-55487568 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047187 Approved Mitochondria Mixed cerebral cortex: 26.8 -PITPNM2 NIR3, RDGB2, RDGBA2 ENSG00000090975 Phosphatidylinositol transfer protein, membrane-associated 2 12 122983480-123150015 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003414, HPA003978 Approved Supported Vesicles Mixed ovary: 19.1 -EXOC1 BM-102, FLJ10893, SEC3, SEC3L1, Sec3p ENSG00000090989 Exocyst complex component 1 4 55853616-55905034 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037706, HPA044873 Uncertain Approved Plasma membrane
Microtubules
Cytosol Expressed in all cerebral cortex: 39.4 -RBM27 ARRS1, KIAA1311, Psc1, ZC3H20 ENSG00000091009 RNA binding motif protein 27 5 146203600-146289132 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035944, HPA036422 Approved Approved Nuclear speckles Expressed in all testis: 18.9 -POU4F3 BRN3C, DFNA15 ENSG00000091010 POU class 4 homeobox 3 5 146339024-146340520 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA038215 Uncertain Supported Nucleoplasm Not detected epididymis: 0.0 -OSBPL8 MST120, MSTP120, ORP8, OSBP10 ENSG00000091039 Oxysterol binding protein-like 8 12 76351797-76559809 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001309 Uncertain Approved Vesicles
Cytosol Expressed in all cerebral cortex: 39.6 -DTX2 KIAA1528, RNF58 ENSG00000091073 Deltex 2, E3 ubiquitin ligase 7 76461676-76505995 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042931 Approved Supported Nucleoplasm
Nuclear membrane Expressed in all esophagus: 37.3 -NLRC4 CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf ENSG00000091106 NLR family, CARD domain containing 4 2 32224453-32265854 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006592 Uncertain Tissue enhanced 0 appendix: 12.7 lung: 9.4 -PUS7 FLJ20485 ENSG00000091127 Pseudouridylate synthase 7 (putative) 7 105439661-105522267 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024116 Approved Approved Nucleus Mixed parathyroid gland: 14.6 -LAMB4 ENSG00000091128 Laminin, beta 4 7 108023548-108130356 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA020242, HPA024247 Approved Uncertain Cytosol Tissue enriched 12 skin: 46.6 placenta: 3.8 -NRCAM Bravo, KIAA0343 ENSG00000091129 Neuronal cell adhesion molecule 7 108147623-108456717 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012606 Approved Tissue enhanced 0 cerebral cortex: 180.9 adrenal gland: 49.7 -LAMB1 CLM ENSG00000091136 Laminin, beta 1 7 107923799-108003255 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004056, HPA004132, CAB004256 Supported Tissue enhanced 0 placenta: 261.4 adipose tissue: 160.4 -SLC26A4 DFNB4, PDS ENSG00000091137 Solute carrier family 26 (anion exchanger), member 4 7 107660635-107717809 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042860 Approved Tissue enriched 28 thyroid gland: 422.9 cerebral cortex: 15.2 -SLC26A3 CLD, DRA ENSG00000091138 Solute carrier family 26 (anion exchanger), member 3 7 107765467-107803225 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036055 Approved Tissue enhanced 0 colon: 1092.5;duodenum: 594.0;rectum: 974.8 seminal vesicle: 183.9 -DLD DLDH, GCSL, LAD ENSG00000091140 Dihydrolipoamide dehydrogenase 7 107890970-107931730 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044849 Supported Supported Mitochondria Expressed in all kidney: 119.6 -WDR7 KIAA0541, TRAG ENSG00000091157 WD repeat domain 7 18 56651343-57036606 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042074 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 38.8 parathyroid gland: 16.7 -TXNL1 TRP32, Txl, TXNL ENSG00000091164 Thioredoxin-like 1 18 56597208-56651600 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002828, HPA002829, CAB016446 Supported Supported Validated Cytosol Expressed in all thyroid gland: 333.1 -IL5RA CD125, CDw125, IL5R ENSG00000091181 Interleukin 5 receptor, alpha 3 3066326-3126613 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 fallopian tube: 22.5 lung: 4.9 -ABCC6 ARA, EST349056, MLP1, MRP6, PXE, URG7 ENSG00000091262 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 16 16148928-16223522 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038105 Supported Plasma membrane Tissue enhanced 0 kidney: 15.2;liver: 19.1 duodenum: 11.6 -CMTM6 CKLFSF6, FLJ20396 ENSG00000091317 CKLF-like MARVEL transmembrane domain containing 6 3 32481312-32503408 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026980 Approved Approved Intermediate filaments
Cytosol Expressed in all fallopian tube: 236.7 -ITGA6 CD49f ENSG00000091409 Integrin, alpha 6 2 172427354-172506282 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009009, HPA012696, HPA027582 Supported Expressed in all placenta: 114.3 -RAPGEF4 cAMP-GEFII, CGEF2 ENSG00000091428 Rap guanine nucleotide exchange factor (GEF) 4 2 172735274-173052893 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004388, HPA028968 Approved Approved Focal adhesion sites Tissue enhanced 0 adrenal gland: 53.6;cerebral cortex: 119.5 liver: 18.2 -AC013461.1 ENSG00000091436 Mitogen-activated protein kinase kinase kinase MLT 2 173075435-173268010 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017205 Approved Supported Cytosol Expressed in all parathyroid gland: 132.2 -SMPX DFN6, DFNX4 ENSG00000091482 Small muscle protein, X-linked X 21705972-21758163 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 21 heart muscle: 422.6;skeletal muscle: 383.2 esophagus: 19.5 -FH fumarase ENSG00000091483 Fumarate hydratase 1 241497603-241519761 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017785, HPA025770, HPA025948, HPA027341 Supported Approved Validated Mitochondria Expressed in all liver: 141.9 -SEL1L3 KIAA0746 ENSG00000091490 Sel-1 suppressor of lin-12-like 3 (C. elegans) 4 25747427-25863760 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040045, HPA058792 Approved Validated Nucleus Expressed in all lymph node: 148.5 -TF PRO1557, PRO2086 ENSG00000091513 Transferrin 3 133745956-133779006 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001527, HPA005692, CAB009538 Supported Uncertain Mitochondria Tissue enriched 14 liver: 5384.6 cerebral cortex: 386.9 -CDV3 H41 ENSG00000091527 CDV3 homolog (mouse) 3 133573730-133590261 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029761, HPA029762, HPA029763 Supported Validated Nucleoli
Plasma membrane
Cytosol Expressed in all lymph node: 187.9 -MYO15A DFNB3, MYO15 ENSG00000091536 Myosin XVA 17 18108706-18179802 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039770 Uncertain Tissue enhanced 0 testis: 10.5 ovary: 2.8 -ALKBH5 FLJ20308, OFOXD1 ENSG00000091542 AlkB homolog 5, RNA demethylase 17 18183078-18209954 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007196 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all testis: 110.7 -APOH B2G1, BG ENSG00000091583 Apolipoprotein H (beta-2-glycoprotein I) 17 66212033-66256525 Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001654, HPA003732, CAB022214 Supported Supported Golgi apparatus Tissue enriched 278 liver: 9066.2 kidney: 32.6 -NLRP1 CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1 ENSG00000091592 NLR family, pyrin domain containing 1 17 5499427-5619424 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009189, HPA064431 Supported Supported Nucleoplasm
Cytosol Mixed skin: 35.2 -PITPNM3 ACKR6, CORD5, NIR1, RDGBA3 ENSG00000091622 PITPNM family member 3 17 6451264-6556494 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022432, HPA059005 Uncertain Approved Plasma membrane Tissue enhanced 0 spleen: 78.2 ovary: 33.8 -SPAG7 ACRP, FSA-1, MGC20134 ENSG00000091640 Sperm associated antigen 7 17 4959226-4967872 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024032, HPA052394 Uncertain Supported Nucleus Expressed in all fallopian tube: 102.0 -ORC6 ORC6L ENSG00000091651 Origin recognition complex, subunit 6 16 46689643-46698394 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016330, HPA072587 Approved Approved Nucleus
Nucleoli fibrillar center Tissue enhanced 0 testis: 12.3 lymph node: 8.9 -ZFHX4 FLJ20980, ZFH4 ENSG00000091656 Zinc finger homeobox 4 8 76681219-76867285 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023837 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center Tissue enhanced 0 testis: 12.2 seminal vesicle: 7.9 -SLC17A6 DNPI, VGLUT2 ENSG00000091664 Solute carrier family 17 (vesicular glutamate transporter), member 6 11 22338097-22379503 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB037130, HPA039226 Supported Supported Tissue enriched 65 cerebral cortex: 6.5 epididymis: 0.0 -CPA1 CPA ENSG00000091704 Carboxypeptidase A1 (pancreatic) 7 130380339-130388114 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021836, CAB025197, HPA052215 Supported Tissue enriched 366 pancreas: 48833.8 ovary: 133.3 -ZC3HC1 NIPA ENSG00000091732 Zinc finger, C3HC-type containing 1 7 130018286-130051451 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019089, HPA024023 Supported Supported Nucleus
Nuclear membrane Expressed in all testis: 26.4 -ESR1 Era, ESR, NR3A1 ENSG00000091831 Estrogen receptor 1 6 151656691-152129619 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB000037, HPA000449, HPA000450, CAB055099, CAB072858 Supported Approved Nucleus
Vesicles Group enriched 8 breast: 37.4;cervix, uterine: 127.3;endometrium: 179.7;fallopian tube: 105.5;smooth muscle: 75.9 seminal vesicle: 13.5 -RGS17 RGS-17, RGSZ2 ENSG00000091844 Regulator of G-protein signaling 17 6 153004459-153131249 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022276, HPA056493 Approved Approved Vesicles Mixed thyroid gland: 5.5 -ANGPT2 Ang2 ENSG00000091879 Angiopoietin 2 8 6499651-6563409 Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011437, CAB017626 Approved Mixed placenta: 19.5 -TMEM101 FLJ23987, MGC4251 ENSG00000091947 Transmembrane protein 101 17 44011188-44023946 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039739 Approved Nucleoplasm
Plasma membrane Expressed in all seminal vesicle: 156.9 -CD200 MOX1, MOX2, MRC, OX-2 ENSG00000091972 CD200 molecule 3 112332347-112362812 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031149 Approved Mixed cerebral cortex: 78.8 -CCDC80 DRO1, SSG1, URB ENSG00000091986 Coiled-coil domain containing 80 3 112596794-112649530 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002266 Approved Mixed smooth muscle: 526.0 -CMA1 ENSG00000092009 Chymase 1, mast cell 14 24505353-24508265 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000363, HPA052634 Supported Tissue enhanced 0 breast: 23.8 esophagus: 11.5 -PSME1 IFI5111, PA28alpha ENSG00000092010 Proteasome activator subunit 1 14 24136158-24138967 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006632 Approved Expressed in all lymph node: 334.5 -PPP2R3C C14orf10, FLJ20644, G4-1, G5PR ENSG00000092020 Protein phosphatase 2, regulatory subunit B'', gamma 14 35085467-35122517 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040835, HPA058834 Approved Approved Nucleus
Golgi apparatus Expressed in all testis: 97.5 -HAUS4 C14orf94, FLJ20424 ENSG00000092036 HAUS augmin-like complex, subunit 4 14 22946228-22957161 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029803, HPA071195 Approved Supported Plasma membrane
Focal adhesion sites Expressed in all ovary: 61.7 -JPH4 JPHL1, KIAA1831 ENSG00000092051 Junctophilin 4 14 23568035-23578800 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB013492, HPA054232 Approved Nucleoplasm
Golgi apparatus Tissue enhanced 0 cerebral cortex: 107.4;seminal vesicle: 51.4 endometrium: 28.0 -MYH7 CMD1S, CMH1, MPD1 ENSG00000092054 Myosin, heavy chain 7, cardiac muscle, beta 14 23412738-23435718 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001239, HPA001349, CAB015384 Supported Group enriched 26 heart muscle: 1925.5;skeletal muscle: 5112.2 esophagus: 136.3 -CEBPE CRP1 ENSG00000092067 CCAAT/enhancer binding protein (C/EBP), epsilon 14 23117304-23119616 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002928, CAB005113 Supported Validated Nucleoplasm Tissue enriched 9 bone marrow: 26.0 small intestine: 2.8 -SLC7A8 LAT2, LPI-PC1 ENSG00000092068 Solute carrier family 7 (amino acid transporter light chain, L system), member 8 14 23125295-23183674 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046015, HPA051950, HPA060672 Supported Tissue enriched 8 parathyroid gland: 1066.4 kidney: 131.5 -OSGEP GCPL1, KAE1, OSGEP1, PRSMG1 ENSG00000092094 O-sialoglycoprotein endopeptidase 14 20446411-20455105 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039751 Uncertain Supported Nucleoplasm
Plasma membrane Mixed thyroid gland: 12.7 -SLC22A17 BOCT, BOIT, NGALR ENSG00000092096 Solute carrier family 22, member 17 14 23346306-23352912 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA002728 Uncertain Tissue enriched 6 cerebral cortex: 229.2 prostate: 38.6 -RNF31 FLJ10111, FLJ23501, HOIP, ZIBRA ENSG00000092098 Ring finger protein 31 14 24146683-24160661 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009063, HPA048745 Approved Approved Cytosol Expressed in all skin: 44.4 -SCFD1 C14orf163, KIAA0917, RA410, SLY1, STXBP1L2 ENSG00000092108 Sec1 family domain containing 1 14 30622112-30735812 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003579 Approved Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 72.8 -G2E3 FLJ20333, KIAA1333, PHF7B ENSG00000092140 G2/M-phase specific E3 ubiquitin protein ligase 14 30559123-30620063 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001601 Uncertain Tissue enriched 6 testis: 80.1 thyroid gland: 12.9 -HECTD1 KIAA1131 ENSG00000092148 HECT domain containing E3 ubiquitin protein ligase 1 14 31100112-31207804 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002929, HPA054461 Approved Supported Nucleus
Nucleoli Expressed in all parathyroid gland: 107.5 -HNRNPC hnRNPC, HNRPC ENSG00000092199 Heterogeneous nuclear ribonucleoprotein C (C1/C2) 14 21209136-21269494 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005223, HPA051075, CAB075755, CAB075756 Supported Validated Nucleoplasm Expressed in all lymph node: 576.3 -RPGRIP1 CORD13, LCA6, RGI1, RPGRIP ENSG00000092200 Retinitis pigmentosa GTPase regulator interacting protein 1 14 21287939-21351301 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042955, HPA060190 Supported Tissue enriched 47 testis: 105.6 spleen: 2.2 -SUPT16H CDC68, FACT, FACTP140, FLJ10857, FLJ14010, SPT16/CDC68 ENSG00000092201 SPT16 homolog, facilitates chromatin remodeling subunit 14 21351472-21384266 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022551, HPA049787 Supported Supported Nucleus
Nucleoli fibrillar center Expressed in all parathyroid gland: 94.3 -TOX4 C14orf92, KIAA0737, LCP1 ENSG00000092203 TOX high mobility group box family member 4 14 21476597-21499175 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017880, HPA027551 Approved Approved Nucleus
Nucleoli
Vesicles Expressed in all parathyroid gland: 34.8 -GEMIN2 SIP1 ENSG00000092208 Gem (nuclear organelle) associated protein 2 14 39114223-39136973 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015426, HPA046570, HPA057114 Supported Supported Nucleus
Nucleoli
Nuclear bodies Expressed in all testis: 17.4 -TGM1 ICR2, LI, LI1, TGASE, TGK ENSG00000092295 Transglutaminase 1 14 24249114-24264432 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015159, HPA040171 Supported Tissue enriched 11 esophagus: 835.1 tonsil: 75.0 -TINF2 TIN2 ENSG00000092330 TERF1 (TRF1)-interacting nuclear factor 2 14 24239643-24242674 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059061, HPA069807 Supported Nuclear bodies Tissue enriched 24 parathyroid gland: 1333.2 smooth muscle: 56.5 -DAZL DAZH, DAZL1, DAZLA, MGC26406, SPGYLA ENSG00000092345 Deleted in azoospermia-like 3 16586792-16670306 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019593, HPA019777, HPA047113 Supported Tissue enriched 147 testis: 141.0 tonsil: 0.9 -TBL1Y TBL1 ENSG00000092377 Transducin (beta)-like 1, Y-linked Y 6910686-7091683 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA060073 Uncertain Tissue enhanced 0 prostate: 2.5;thyroid gland: 1.4 testis: 0.5 -SEMA6A HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ ENSG00000092421 Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 5 116443616-116574934 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031265, HPA031267 Approved Supported Nucleus
Intermediate filaments Expressed in all adrenal gland: 49.3 -TRPM7 CHAK1, LTRPC7, TRP-PLIK ENSG00000092439 Transient receptor potential cation channel, subfamily M, member 7 15 50552473-50686815 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035523, HPA052173 Uncertain Approved Nucleoplasm Tissue enriched 7 parathyroid gland: 212.8 thyroid gland: 29.0 -TYRO3 Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif ENSG00000092445 TYRO3 protein tyrosine kinase 15 41557675-41583586 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071245 Approved Tissue enhanced 0 cerebral cortex: 67.6;ovary: 61.4 testis: 36.9 -WDR76 FLJ12973 ENSG00000092470 WD repeat domain 76 15 43826963-43868419 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039804, HPA040626 Uncertain Approved Nucleoli fibrillar center
Nuclear bodies Mixed lymph node: 24.0 -CAPN3 CANP3, LGMD2, LGMD2A, nCL-1, p94 ENSG00000092529 Calpain 3 15 42359500-42412318 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040052 Approved Expressed in all skeletal muscle: 357.7 -SNAP23 HsT17016, SNAP23A, SNAP23B ENSG00000092531 Synaptosomal-associated protein, 23kDa 15 42491233-42545356 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001214, CAB037083, CAB037317 Approved Supported Plasma membrane Expressed in all spleen: 88.1 -TBX15 TBX14 ENSG00000092607 T-box 15 1 118883046-118989556 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA052245, HPA053713 Uncertain Approved Nucleoplasm
Centrosome Group enriched 7 adipose tissue: 17.0;breast: 8.8;liver: 24.1;skeletal muscle: 42.2 lymph node: 3.2 -PHGDH PDG, PGDH, SERA ENSG00000092621 Phosphoglycerate dehydrogenase 1 119659798-119744215 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003681, HPA021241, HPA024031, CAB068216 Supported Validated Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 parathyroid gland: 212.4 skin: 116.1 -COL9A3 DJ885L7.4.1, EDM3, FLJ90759, IDD, MED ENSG00000092758 Collagen, type IX, alpha 3 20 62816244-62841159 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040125, HPA058323 Uncertain Approved Nucleoplasm
Intermediate filaments Group enriched 6 cerebral cortex: 7.5;salivary gland: 10.5;testis: 6.4;thyroid gland: 19.3 seminal vesicle: 1.8 -EZR VIL2 ENSG00000092820 Ezrin 6 158765741-158819412 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004035, HPA021616, CAB047324 Supported Validated Plasma membrane Expressed in all parathyroid gland: 528.6 -MYL6 ESMLC, MLC1SM, MLC3NM ENSG00000092841 Myosin, light chain 6, alkali, smooth muscle and non-muscle 12 56158161-56163496 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046859, HPA063034 Approved Expressed in all smooth muscle: 5900.6 -AGO1 EIF2C1, hAGO1 ENSG00000092847 Argonaute RISC catalytic component 1 1 35869808-35930528 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 15.8 -TEKT2 TEKTB1 ENSG00000092850 Tektin 2 (testicular) 1 36084075-36088275 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027248, HPA027461 Approved Uncertain Microtubules Group enriched 9 fallopian tube: 96.6;testis: 63.3 lung: 8.8 -CLSPN ENSG00000092853 Claspin 1 35720218-35769967 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026305, HPA026312 Validated Nucleoplasm
Golgi apparatus Tissue enhanced 0 testis: 10.6 bone marrow: 7.1 -RFFL fring, rififylin, RNF189, RNF34L ENSG00000092871 Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 17 35005990-35089319 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008096, HPA017910, HPA019492 Approved Approved Vesicles Expressed in all thyroid gland: 53.9 -UNC13D Munc13-4 ENSG00000092929 Unc-13 homolog D (C. elegans) 17 75827225-75844717 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067117, HPA073525 Supported Cytosol Mixed spleen: 39.2 -MFSD11 FLJ20226, FLJ22196 ENSG00000092931 Major facilitator superfamily domain containing 11 17 76735865-76781449 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA022001 Uncertain Approved Nuclear speckles Expressed in all parathyroid gland: 33.9 -DPYSL2 CRMP2, DHPRP2, DRP-2, DRP2 ENSG00000092964 Dihydropyrimidinase-like 2 8 26514275-26658178 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002381, CAB018719 Supported Supported Plasma membrane
Cytosol Expressed in all cerebral cortex: 381.2 -TGFB2 ENSG00000092969 Transforming growth factor, beta 2 1 218346235-218444619 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 prostate: 28.3 placenta: 20.2 -GPATCH2 CT110, FLJ10252, GPATC2, PPP1R30 ENSG00000092978 G patch domain containing 2 1 217426992-217631082 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027181, HPA027322 Uncertain Supported Nuclear speckles Mixed parathyroid gland: 11.7 -NUP50 NPAP60L ENSG00000093000 Nucleoporin 50kDa 22 45163841-45188015 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047162, HPA048328 Supported Validated Nucleoplasm
Nuclear membrane Expressed in all testis: 54.5 -CDC45 CDC45L, CDC45L2 ENSG00000093009 Cell division cycle 45 22 19479459-19520612 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000614, CAB009459 Supported Supported Nucleoplasm
Centrosome
Cytosol Tissue enhanced 0 testis: 37.6 bone marrow: 15.3 -COMT ENSG00000093010 Catechol-O-methyltransferase 22 19941607-19969975 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001169, CAB011233 Supported Approved Endoplasmic reticulum
Vesicles Expressed in all placenta: 172.0 -CECR1 ADGF, IDGFL ENSG00000093072 Cat eye syndrome chromosome region, candidate 1 22 17178790-17221989 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007888 Approved Expressed in all spleen: 164.1 -VNN3 HSA238982 ENSG00000093134 Vanin 3 6 132722787-132734765 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA010818 Uncertain Tissue enhanced 0 bone marrow: 35.4;liver: 15.2 spleen: 9.6 -ECHDC1 dJ351K20.2 ENSG00000093144 Ethylmalonyl-CoA decarboxylase 1 6 127288710-127343609 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035445 Uncertain Expressed in all adipose tissue: 98.7 -LRRFIP2 HUFI-2 ENSG00000093167 Leucine rich repeat (in FLII) interacting protein 2 3 37052656-37183689 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035956, HPA042023 Uncertain Approved Plasma membrane
Actin filaments Expressed in all testis: 130.5 -SEC22C MGC13261, MGC5373, SEC22L3 ENSG00000093183 SEC22 homolog C, vesicle trafficking protein 3 42547969-42601080 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055594 Approved Golgi apparatus Expressed in all prostate: 66.4 -XYLB FLJ10343, FLJ12539 ENSG00000093217 Xylulokinase homolog (H. influenzae) 3 38346760-38421348 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037863, HPA038415 Uncertain Approved Nuclear speckles Tissue enhanced 0 liver: 15.3 kidney: 9.9 -HDAC6 FLJ16239, HD6, JM21, KIAA0901, PPP1R90 ENSG00000094631 Histone deacetylase 6 X 48801377-48824982 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003714, CAB004236, HPA026321 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 50.4 -OR1I1 OR19-20, OR1I1P, OR1I1Q ENSG00000094661 Olfactory receptor, family 1, subfamily I, member 1 19 15086980-15088221 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -GABRP ENSG00000094755 Gamma-aminobutyric acid (GABA) A receptor, pi 5 170763350-170814047 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB014883 Uncertain Expressed in all breast: 186.6 -KRT31 Ha-1, KRTHA1 ENSG00000094796 Keratin 31, type I 17 41393724-41397592 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049550, HPA055194 Supported Group enriched 6 esophagus: 4.7;skin: 14.4 skeletal muscle: 1.5 -CDC6 CDC18L ENSG00000094804 Cell division cycle 6 17 40287633-40304657 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050114, HPA054703 Approved Supported Nucleoplasm
Golgi apparatus
Cytosol Mixed appendix: 15.8 -UPRT DKFZp781E1243, FUR1, MGC23937, RP11-311P8.3 ENSG00000094841 Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) X 75274085-75304600 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000805 Uncertain Approved Vesicles Expressed in all parathyroid gland: 21.1 -CDC23 ANAPC8, APC8, CUT23 ENSG00000094880 Cell division cycle 23 5 138187648-138213343 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039593 Approved Expressed in all placenta: 37.1 -AAAS ENSG00000094914 Achalasia, adrenocortical insufficiency, alacrimia 12 53307456-53324864 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040086 Approved Approved Nuclear membrane
Centrosome
Cytosol Expressed in all parathyroid gland: 44.9 -CBX5 HP1, HP1-ALPHA, HP1Hs-alpha ENSG00000094916 Chromobox homolog 5 12 54230940-54280133 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016699, CAB017548 Supported Validated Nucleus Expressed in all parathyroid gland: 57.3 -FMO2 ENSG00000094963 Flavin containing monooxygenase 2 (non-functional) 1 171185208-171211230 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028261 Approved Tissue enhanced 0 adipose tissue: 98.1;esophagus: 103.4;lung: 158.2 breast: 56.2 -SUCO C1orf9, CH1, OPT, SLP1 ENSG00000094975 SUN domain containing ossification factor 1 172532349-172611833 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047251 Approved Approved Nucleoli fibrillar center
Cytosol Mixed epididymis: 75.0 -MSH2 COCA1, HNPCC, HNPCC1 ENSG00000095002 MutS homolog 2 2 47402969-47562311 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009572, CAB070867 Supported Approved Nucleoplasm
Vesicles Expressed in all testis: 32.6 -MAP3K1 MAPKKK1, MEKK, MEKK1 ENSG00000095015 Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 5 56815574-56896152 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004500, HPA046509 Approved Approved Cytosol Mixed spleen: 28.7 -DHPS MIG13 ENSG00000095059 Deoxyhypusine synthase 19 12675717-12681902 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014461, HPA029413 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all fallopian tube: 63.4 -HOOK2 HK2 ENSG00000095066 Hook microtubule-tethering protein 2 19 12763003-12872740 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043519, HPA050351 Approved Supported Vesicles
Cytosol Expressed in all thyroid gland: 95.9 -NXPE1 FAM55A, MGC34290 ENSG00000095110 Neurexophilin and PC-esterase domain family, member 1 11 114521715-114559895 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049133 Supported Group enriched 13 colon: 114.0;rectum: 168.7 appendix: 11.0 -ARCN1 COPD ENSG00000095139 Archain 1 11 118572390-118603033 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037573, HPA044874 Approved Validated Golgi apparatus
Vesicles Expressed in all parathyroid gland: 142.0 -EPB41L4B EHM2 ENSG00000095203 Erythrocyte membrane protein band 4.1 like 4B 9 109171975-109320964 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042862 Approved Approved Plasma membrane
Cytosol Mixed thyroid gland: 74.5 -TMEM38B bA219P18.1, C9orf87, D4Ertd89e, FLJ10493, TRIC-B ENSG00000095209 Transmembrane protein 38B 9 105694544-105776612 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018465 Uncertain Expressed in all testis: 51.9 -PSMD5 KIAA0072, S5B ENSG00000095261 Proteasome 26S subunit, non-ATPase 5 9 120815496-120842984 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003216 Uncertain Approved Nucleus
Cytosol Expressed in all breast: 28.7 -PTGS1 COX1, PGHS-1, PTGHS ENSG00000095303 Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 9 122370530-122395703 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002834, CAB020315 Supported Supported Golgi apparatus
Vesicles Tissue enhanced 0 skin: 161.9 esophagus: 85.8 -NUP188 KIAA0169 ENSG00000095319 Nucleoporin 188kDa 9 128947699-129007096 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061750, HPA063942 Approved Supported Nucleus Expressed in all testis: 104.4 -CRAT CAT1 ENSG00000095321 Carnitine O-acetyltransferase 9 129094810-129111189 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019230, HPA020260, HPA022815 Supported Approved Nucleoplasm
Nuclear membrane Expressed in all testis: 116.2 -SH2D3C NSP3 ENSG00000095370 SH2 domain containing 3C 9 127738317-127778741 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047586 Approved Mixed spleen: 50.6 -NANS SAS ENSG00000095380 N-acetylneuraminic acid synthase 9 98056739-98083075 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019223 Approved Approved Nucleoplasm Expressed in all prostate: 149.7 -TBC1D2 Armus, PARIS1, TBC1D2A ENSG00000095383 TBC1 domain family, member 2 9 98198999-98255721 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030871 Uncertain Approved Nucleus
Cytosol Mixed lung: 33.3 -DFNB31 CIP98, PDZD7B, USH2D, WHRN ENSG00000095397 Deafness, autosomal recessive 31 9 114402080-114505450 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002480, CAB033194 Uncertain Tissue enhanced 0 adrenal gland: 73.4 testis: 44.5 -PDE6C ACHM5, COD4, PDEA2 ENSG00000095464 Phosphodiesterase 6C, cGMP-specific, cone, alpha prime 10 93612588-93666010 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected skin: 0.6 -CWF19L1 FLJ10998 ENSG00000095485 CWF19-like 1, cell cycle control (S. pombe) 10 100232298-100267680 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036889, HPA036890 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all testis: 26.0 -SEMA4G FLJ20590, KIAA1619 ENSG00000095539 Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G 10 100969518-100985871 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038362 Uncertain Tissue enhanced 0 rectum: 94.4 duodenum: 55.4 -BTAF1 MOT1, TAF(II)170, TAF-172, TAF172, TAFII170 ENSG00000095564 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 10 91923769-92030325 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA070682 Approved Nucleoplasm
Vesicles Expressed in all skin: 59.9 -IKZF5 FLJ22973, Pegasus, ZNFN1A5 ENSG00000095574 IKAROS family zinc finger 5 (Pegasus) 10 122990806-123008817 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA015297, HPA051574 Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all bone marrow: 21.4 -BLNK BASH, bca, BLNK-s, Ly57, SLP-65, SLP65 ENSG00000095585 B-cell linker 10 96191702-96271587 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009333, CAB016291, HPA038309, HPA038310 Supported Supported Nucleoplasm
Cytosol Mixed spleen: 70.1 -TLL2 ENSG00000095587 Tolloid-like 2 10 96364606-96513918 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 1.9 heart muscle: 0.9 -CYP26A1 CP26, CYP26, P450RAI, P450RAI1 ENSG00000095596 Cytochrome P450, family 26, subfamily A, polypeptide 1 10 93073475-93077890 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 9 liver: 9.7 cerebral cortex: 1.0 -TDRD1 CT41.1 ENSG00000095627 Tudor domain containing 1 10 114179270-114232304 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037729, HPA037730 Uncertain Tissue enriched 13 testis: 31.9 kidney: 2.3 -SORBS1 CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12 ENSG00000095637 Sorbin and SH3 domain containing 1 10 95311771-95561414 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027559, HPA043084 Approved Supported Plasma membrane
Focal adhesion sites
Centrosome Expressed in all adipose tissue: 318.9 -CRTAC1 ASPIC1, CEP-68, FLJ10320 ENSG00000095713 Cartilage acidic protein 1 10 97865000-98030828 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008175 Approved Tissue enhanced 0 cerebral cortex: 51.1;fallopian tube: 62.9;lung: 76.5;seminal vesicle: 47.6 urinary bladder: 13.3 -BAMBI NMA ENSG00000095739 BMP and activin membrane-bound inhibitor 10 28677342-28682939 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA010819, HPA010866 Approved Approved Nucleoli fibrillar center
Vesicles
Lipid droplets Tissue enhanced 0 ovary: 87.4 adrenal gland: 50.1 -IL11 AGIF, IL-11 ENSG00000095752 Interleukin 11 19 55364389-55370463 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044955 Uncertain Mitochondria Tissue enhanced 0 appendix: 5.8;endometrium: 5.2;gallbladder: 4.9 skin: 1.7 -MYO3A DFNB30 ENSG00000095777 Myosin IIIA 10 25934267-26212527 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048951, HPA051893 Approved Supported Plasma membrane
Actin filaments
Cytoplasmic bodies Tissue enriched 9 testis: 6.8 skin: 0.8 -WAC BM-016, FLJ31290, MGC10753, PRO1741, Wwp4 ENSG00000095787 WW domain containing adaptor with coiled-coil 10 28532493-28623112 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036528, HPA042609 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 129.7 -CREM hCREM-2 ENSG00000095794 CAMP responsive element modulator 10 35126791-35212958 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001818, CAB018352 Supported Supported Nucleus
Vesicles Expressed in all testis: 337.8 -NUBP2 CFD1 ENSG00000095906 Nucleotide binding protein 2 16 1782901-1789191 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041704 Uncertain Approved Nucleus
Cytosol Expressed in all spleen: 17.8 -TPSD1 ENSG00000095917 Tryptase delta 1 16 1256059-1258998 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB002215, CAB032871, HPA040182, HPA049554 Supported Tissue enhanced 0 lung: 26.9 gallbladder: 20.5 -SMIM24 C19orf77, HSPC323 ENSG00000095932 Small integral membrane protein 24 19 3473986-3480542 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045046, HPA056027 Supported Approved Nucleoplasm
Cytosol Group enriched 8 duodenum: 780.7;epididymis: 1898.5;kidney: 832.6;small intestine: 696.9 stomach: 139.3 -HIVEP1 CIRIP, CRYBP1, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A ENSG00000095951 Human immunodeficiency virus type I enhancer binding protein 1 6 12008762-12164999 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050724 Approved Supported Nucleoplasm
Nuclear bodies
Mitochondria Mixed parathyroid gland: 25.7 -TREM2 TREM-2, Trem2a, Trem2b, Trem2c ENSG00000095970 Triggering receptor expressed on myeloid cells 2 6 41158506-41163186 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA010917, HPA012571 Approved Supported Vesicles Tissue enhanced 0 cerebral cortex: 37.1;lung: 40.5 adrenal gland: 16.2 -KCNK16 K2p16.1, TALK-1, TALK1 ENSG00000095981 Potassium channel, two pore domain subfamily K, member 16 6 39314698-39322968 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 duodenum: 3.9;pancreas: 5.4;stomach: 12.6 thyroid gland: 1.7 -CRISP3 Aeg2, CRISP-3, CRS3, dJ442L6.3, SGP28 ENSG00000096006 Cysteine-rich secretory protein 3 6 49727384-49744437 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054392 Supported Tissue enhanced 0 fallopian tube: 1867.9;salivary gland: 923.6 esophagus: 289.4 -FKBP5 FKBP51, FKBP54, P54, PPIase, Ptg-10 ENSG00000096060 FK506 binding protein 5 6 35573585-35728583 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009315, HPA031092, HPA031093, HPA031095 Supported Validated Nucleoplasm Expressed in all adipose tissue: 414.0 -SRPK1 SFRSK1 ENSG00000096063 SRSF protein kinase 1 6 35832966-35921342 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016431, HPA056486 Approved Supported Nucleus
Plasma membrane
Cytosol Expressed in all testis: 81.8 -BRPF3 KIAA1286 ENSG00000096070 Bromodomain and PHD finger containing, 3 6 36196744-36232790 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022787 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all testis: 38.2 -MRPS18A FLJ10548, MRPS18-3 ENSG00000096080 Mitochondrial ribosomal protein S18A 6 43671303-43687791 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035450, HPA035451 Approved Expressed in all prostate: 60.4 -PGC ENSG00000096088 Progastricsin (pepsinogen C) 6 41736711-41754109 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031717, HPA031718 Supported Supported Nucleus Tissue enriched 16 stomach: 22057.0 duodenum: 1339.7 -TMEM14A C6orf73, PTD011 ENSG00000096092 Transmembrane protein 14A 6 52671109-52686588 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072536 Approved Nucleoplasm
Endoplasmic reticulum Expressed in all cerebral cortex: 88.4 -EFHC1 EJM, EJM1, FLJ10466 ENSG00000096093 EF-hand domain (C-terminal) containing 1 6 52420308-52495785 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035307 Approved Approved Plasma membrane
Cytosol Tissue enhanced 0 fallopian tube: 27.2 thyroid gland: 7.5 -NCR2 CD336, LY95, NK-p44 ENSG00000096264 Natural cytotoxicity triggering receptor 2 6 41335655-41350887 CD markers, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level HPA067249 Uncertain Not detected duodenum: 0.5 -HSP90AB1 HSPC2, HSPCB ENSG00000096384 Heat shock protein 90kDa alpha (cytosolic), class B member 1 6 44246166-44253888 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005230, HPA055729 Approved Validated Cytosol Expressed in all ovary: 1457.6 -MLN ENSG00000096395 Motilin 6 33794673-33804011 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069392 Supported Tissue enriched 6 duodenum: 260.7 small intestine: 43.6 -CDC5L CDC5, CEF1, hCDC5, PCDC5RP ENSG00000096401 Cell division cycle 5-like 6 44387525-44450426 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006302, HPA011361, CAB012275 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 35.6 -ITPR3 IP3R3 ENSG00000096433 Inositol 1,4,5-trisphosphate receptor, type 3 6 33620365-33696574 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003915, HPA064704 Approved Uncertain Vesicles Mixed skin: 65.2 -ZNF184 ENSG00000096654 Zinc finger protein 184 6 27450743-27473118 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003226 Uncertain Approved Nucleus
Cytosol Mixed testis: 15.2 -DSP DPI, DPII, KPPS2, PPKS2 ENSG00000096696 Desmoplakin 6 7541575-7586717 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037324, HPA045840, HPA054950 Supported Validated Cell Junctions Group enriched 8 esophagus: 346.9;skin: 1019.0 placenta: 88.5 -SIRT1 SIR2L1 ENSG00000096717 Sirtuin 1 10 67884669-67918390 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003855, HPA006295, HPA052351 Approved Validated Nucleus
Mitochondria
Cytosol Expressed in all testis: 48.8 -HNRNPH3 2H9, HNRPH3 ENSG00000096746 Heterogeneous nuclear ribonucleoprotein H3 (2H9) 10 68331174-68343191 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038264 Supported Nucleoplasm Expressed in all endometrium: 153.7 -IFT74 CCDC2, CMG-1, CMG1, FLJ22621 ENSG00000096872 Intraflagellar transport 74 9 26947039-27062930 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020247, HPA026684 Approved Approved Golgi apparatus Expressed in all testis: 83.7 -JAK2 JTK10 ENSG00000096968 Janus kinase 2 9 4985033-5128183 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013089, HPA040820, HPA043870 Approved Supported Nucleoplasm
Plasma membrane
Focal adhesion sites Mixed appendix: 25.4 -IL12RB1 CD212, IL12RB ENSG00000096996 Interleukin 12 receptor, beta 1 19 18058995-18098944 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA074414 Approved Plasma membrane Tissue enhanced 0 lymph node: 26.3 spleen: 21.1 -ABL1 ABL, c-ABL, JTK7, p150 ENSG00000097007 ABL proto-oncogene 1, non-receptor tyrosine kinase 9 130713946-130887675 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002686, HPA027251, HPA027280, HPA028409 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 82.2 -ACOT7 ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126 ENSG00000097021 Acyl-CoA thioesterase 7 1 6264269-6394391 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025735, HPA025762 Supported Supported Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 129.6 small intestine: 63.6 -SH3GLB1 Bif-1, CGI-61, KIAA0491, PPP1R70 ENSG00000097033 SH3-domain GRB2-like endophilin B1 1 86704570-86748184 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004650, HPA015608, HPA019900 Supported Supported Cytosol Expressed in all testis: 197.5 -CDC7 CDC7L1, HsCdc7, Hsk1, huCdc7 ENSG00000097046 Cell division cycle 7 1 91500893-91525764 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002669, HPA035831 Approved Supported Nucleoplasm
Cytokinetic bridge
Mitotic spindle Tissue enhanced 0 testis: 31.9 spleen: 17.4 -SYDE2 FLJ13815 ENSG00000097096 Synapse defective 1, Rho GTPase, homolog 2 (C. elegans) 1 85156873-85201046 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027138, HPA058378 Uncertain Approved Nucleoli
Golgi apparatus Mixed parathyroid gland: 6.9 -PCSK5 PC5, PC6, SPC6 ENSG00000099139 Proprotein convertase subtilisin/kexin type 5 9 75890644-76362339 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031072 Supported Supported Golgi apparatus Mixed small intestine: 28.7 -SCD FADS5, SCDOS ENSG00000099194 Stearoyl-CoA desaturase (delta-9-desaturase) 10 100347124-100364834 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012107, HPA063921 Uncertain Validated Endoplasmic reticulum Expressed in all adipose tissue: 1252.9 -TMED1 Il1rl1l, IL1RL1LG, MGC1270, p24g1, p24gamma1, ST2L ENSG00000099203 Transmembrane p24 trafficking protein 1 19 10832438-10836318 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018507, HPA078574 Uncertain Supported Vesicles Expressed in all thyroid gland: 47.6 -ABLIM1 ABLIM, LIMAB1, limatin ENSG00000099204 Actin binding LIM protein 1 10 114431113-114685003 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038951, HPA038952 Approved Supported Cytosol Expressed in all ovary: 283.7 -ERMP1 FLJ23309, FXNA, KIAA1815 ENSG00000099219 Endoplasmic reticulum metallopeptidase 1 9 5765076-5833117 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020584 Approved Approved Nucleus
Nucleoli Tissue enhanced 0 parathyroid gland: 122.3 thyroid gland: 43.8 -RAB18 ENSG00000099246 RAB18, member RAS oncogene family 10 27504174-27542237 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025928 Uncertain Expressed in all cerebral cortex: 88.2 -NRP1 CD304, NRP, VEGF165R ENSG00000099250 Neuropilin 1 10 33177492-33336262 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004511, HPA030278 Approved Uncertain Mitochondria Expressed in all placenta: 193.5 -PRTFDC1 HHGP ENSG00000099256 Phosphoribosyl transferase domain containing 1 10 24848607-24952604 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021458 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Mixed cerebral cortex: 47.6 -PALMD C1orf11, FLJ20271, PALML ENSG00000099260 Palmdelphin 1 99645943-99694541 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017959, HPA030549 Approved Supported Plasma membrane
Actin filaments
Focal adhesion sites Tissue enhanced 0 adipose tissue: 140.7 placenta: 60.0 -TSPAN15 NET-7, TM4SF15 ENSG00000099282 Tetraspanin 15 10 69451473-69507669 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044657 Approved Approved Nucleoplasm
Cytosol Mixed stomach: 73.0 -H2AFY2 macroH2A2 ENSG00000099284 H2A histone family, member Y2 10 70052796-70112280 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035865, HPA041189 Supported Validated Nucleoplasm Expressed in all endometrium: 31.3 -FAM21A bA56A21.1, bA98I6.1, FAM21B, FLJ10824 ENSG00000099290 Family with sequence similarity 21, member A 10 50067888-50133506 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047844, HPA060975 Approved Supported Nucleoli
Vesicles
Cytosol Expressed in all heart muscle: 45.0 -MAST3 KIAA0561 ENSG00000099308 Microtubule associated serine/threonine kinase 3 19 18097793-18151692 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035061, HPA035062 Uncertain Approved Nuclear speckles Expressed in all cerebral cortex: 51.6 -MZF1 MZF-1, MZF1B, Zfp98, ZNF42, ZSCAN6 ENSG00000099326 Myeloid zinc finger 1 19 58561931-58573575 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001757 Approved Supported Nucleus Expressed in all parathyroid gland: 14.7 -OCEL1 FLJ22709 ENSG00000099330 Occludin/ELL domain containing 1 19 17226204-17229219 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042070, HPA043223 Uncertain Approved Golgi apparatus Expressed in all epididymis: 21.9 -MYO9B CELIAC4 ENSG00000099331 Myosin IXB 19 17075781-17214537 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037190, HPA042043 Approved Supported Cytosol Expressed in all spleen: 100.6 -KCNK6 K2p6.1, TWIK-2 ENSG00000099337 Potassium channel, two pore domain subfamily K, member 6 19 38319844-38332076 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level CAB022637, HPA040184 Uncertain Approved Plasma membrane
Actin filaments
Cytosol Mixed endometrium: 22.8 -CATSPERG C19orf15, DKFZp434A1022, FLJ46353 ENSG00000099338 Catsper channel auxiliary subunit gamma 19 38335775-38370943 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052777 Approved Nucleus
Nucleoli
Cytosol Tissue enriched 41 testis: 48.5 skin: 1.1 -PSMD8 HIP6, HYPF, Nin1p, p31, Rpn12, S14 ENSG00000099341 Proteasome 26S subunit, non-ATPase 8 19 38374536-38383824 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006702, CAB021101 Supported Approved Nuclear speckles
Cytosol Expressed in all testis: 194.6 -FBXL19 CXXC11, DKFZp434K0410, Fbl19, JHDM1C ENSG00000099364 F-box and leucine-rich repeat protein 19 16 30923055-30948783 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035317 Approved Intermediate filaments Expressed in all testis: 36.1 -STX1B STX1B1, STX1B2 ENSG00000099365 Syntaxin 1B 16 30989256-31010628 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069176 Supported Tissue enriched 21 cerebral cortex: 89.7 testis: 4.3 -HSD3B7 C(27)-3BETA-HSD, SDR11E3 ENSG00000099377 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 16 30985207-30989152 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050521, HPA060847 Uncertain Supported Lipid droplets Expressed in all liver: 21.9 -SETD1A KIAA0339, KMT2F, Set1 ENSG00000099381 SET domain containing 1A 16 30957294-30985116 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020646, HPA058376 Supported Supported Nuclear speckles Expressed in all testis: 24.7 -BCL7C ENSG00000099385 B-cell CLL/lymphoma 7C 16 30833626-30894960 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018676, HPA052654 Uncertain Approved Nucleoplasm Expressed in all ovary: 30.3 -MAGEB2 CT3.2, DAM6, MAGE-XP-2, MGC26438 ENSG00000099399 Melanoma antigen family B2 X 30215560-30220089 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065224 Approved Nucleoplasm
Vesicles
Cytosol Tissue enriched 74 testis: 54.0 placenta: 0.7 -EFNA2 ELF-1, EPLG6, LERK6 ENSG00000099617 Ephrin-A2 19 1286154-1300237 Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB005178 Uncertain Group enriched 6 colon: 7.1;duodenum: 8.2;small intestine: 10.8 rectum: 1.5 -CIRBP CIRP ENSG00000099622 Cold inducible RNA binding protein 19 1259384-1274880 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060537 Supported Nucleus
Nucleoli Expressed in all ovary: 1040.0 -ATP5D ENSG00000099624 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 19 1241746-1244826 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002865 Uncertain Expressed in all skeletal muscle: 217.7 -CBARP BARP, C19orf26, DOS, MGC40084 ENSG00000099625 Calcium channel, voltage-dependent, beta subunit associated regulatory protein 19 1228287-1238027 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA012777 Uncertain Approved Nucleoplasm Tissue enhanced 0 adrenal gland: 2.4;cerebral cortex: 7.0 testis: 1.1 -PCDH11Y PCDH22, PCDHY ENSG00000099715 Protocadherin 11 Y-linked Y 5000226-5742224 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA000432 Uncertain Tissue enriched 6 cerebral cortex: 4.4 seminal vesicle: 0.7 -AMELY AMGL ENSG00000099721 Amelogenin, Y-linked Y 6865918-6874027 Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level Not detected thyroid gland: 0.2 -IGFALS ALS ENSG00000099769 Insulin-like growth factor binding protein, acid labile subunit 16 1790413-1794971 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040692, HPA040948 Approved Supported Nucleoplasm Group enriched 6 liver: 25.1;stomach: 6.6 gallbladder: 2.5 -HNRNPM CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1 ENSG00000099783 Heterogeneous nuclear ribonucleoprotein M 19 8444767-8489114 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016113, HPA024344 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 200.3 -MARCH2 HSPC240, MARCH-II, RNF172 ENSG00000099785 Membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase 19 8413270-8439017 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014063 Approved Uncertain Cytosol Expressed in all epididymis: 63.9 -NDUFB7 B18, CI-B18, MGC2480 ENSG00000099795 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 19 14566078-14572062 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002817 Approved Expressed in all skeletal muscle: 248.7 -TECR GPSN2, MRT14, SC2, TER ENSG00000099797 Trans-2,3-enoyl-CoA reductase 19 14517085-14565980 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029780, HPA056488 Supported Supported Endoplasmic reticulum Expressed in all parathyroid gland: 397.0 -TIMM13 Tim13, TIMM13B ENSG00000099800 Translocase of inner mitochondrial membrane 13 homolog (yeast) 19 2425624-2427894 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048985 Uncertain Supported Nucleoli fibrillar center
Mitochondria Expressed in all adrenal gland: 53.3 -CDC34 E2-CDC34, UBC3, UBE2R1 ENSG00000099804 Cell division cycle 34 19 531712-542092 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002382, CAB005109, CAB047311 Approved Supported Nuclear speckles
Cytosol Expressed in all testis: 63.5 -MTAP c86fus, MSAP ENSG00000099810 Methylthioadenosine phosphorylase 9 21802543-21937651 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046915 Supported Cytosol Expressed in all parathyroid gland: 16.1 -MISP C19orf21, Caprice, DKFZp686H18209 ENSG00000099812 Mitotic spindle positioning 19 751126-764318 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049511, HPA062232 Supported Validated Plasma membrane
Focal adhesion sites Group enriched 6 colon: 96.4;duodenum: 178.1;rectum: 53.5;small intestine: 221.5 stomach: 22.1 -CEP170B Cep170R, FAM68C, KIAA0284 ENSG00000099814 Centrosomal protein 170B 14 104865280-104896770 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000871, HPA059017 Approved Approved Centrosome
Cytosol Mixed skin: 30.6 -POLR2E hRPB25, hsRPB5, RPABC1, RPB5, XAP4 ENSG00000099817 Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 19 1086579-1095380 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063030, HPA068992 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 42.0 -POLRMT APOLMT, h-mtRPOL, MTRNAP, MTRPOL ENSG00000099821 Polymerase (RNA) mitochondrial (DNA directed) 19 617224-633604 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006366 Uncertain Supported Mitochondria Expressed in all testis: 46.6 -HCN2 BCNG-2, BCNG2, HAC-1 ENSG00000099822 Hyperpolarization activated cyclic nucleotide gated potassium channel 2 19 589893-617159 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 7 cerebral cortex: 38.5;heart muscle: 8.1 testis: 3.4 -CDHR5 FLJ20219, MU-PCDH, MUCDHL, MUPCDH ENSG00000099834 Cadherin-related family member 5 11 616565-626078 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009081, HPA009173, CAB025004 Supported Group enriched 9 colon: 42.5;duodenum: 85.2;kidney: 23.4;liver: 20.6;rectum: 55.1;small intestine: 65.8 gallbladder: 5.3 -IZUMO4 C19orf36 ENSG00000099840 IZUMO family member 4 19 2096429-2099593 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045099, HPA048496 Approved Uncertain Nucleoplasm
Vesicles Tissue enriched 52 testis: 341.4 ovary: 6.5 -RASSF7 C11orf13, HRAS1, HRC1 ENSG00000099849 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 11 560404-564021 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA078015 Supported Microtubule organizing center Mixed fallopian tube: 43.9 -GADD45B DKFZP566B133, GADD45BETA, MYD118 ENSG00000099860 Growth arrest and DNA-damage-inducible, beta 19 2476122-2478259 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029816 Approved Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 218.5 -PALM KIAA0270 ENSG00000099864 Paralemmin 19 708939-748329 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041713, HPA049578 Approved Validated Nucleus
Plasma membrane Tissue enhanced 0 cerebral cortex: 85.1 adipose tissue: 52.9 -MADCAM1 MACAM1 ENSG00000099866 Mucosal vascular addressin cell adhesion molecule 1 19 489176-505342 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 18.5;spleen: 11.7 gallbladder: 3.3 -MKNK2 GPRK7, MNK2 ENSG00000099875 MAP kinase interacting serine/threonine kinase 2 19 2037465-2051244 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021875, CAB037253, HPA053989 Supported Supported Nucleus
Nucleoli
Nuclear bodies Expressed in all skeletal muscle: 174.4 -ARVCF ENSG00000099889 Armadillo repeat gene deleted in velocardiofacial syndrome 22 19969896-20016808 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016162, HPA055264, HPA063675 Approved Supported Nuclear speckles
Plasma membrane
Cell Junctions Mixed spleen: 9.0 -TRMT2A HTF9C ENSG00000099899 TRNA methyltransferase 2 homolog A 22 20111866-20117392 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001077 Approved Approved Nucleus
Cytosol Expressed in all spleen: 16.9 -RANBP1 HTF9A ENSG00000099901 RAN binding protein 1 22 20115938-20127357 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046463, HPA065868, HPA065931 Approved Supported Cytosol Expressed in all testis: 152.3 -ZDHHC8 KIAA1292, ZNF378 ENSG00000099904 Zinc finger, DHHC-type containing 8 22 20129456-20148007 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA003422 Uncertain Approved Nucleoplasm
Cytosol Expressed in all spleen: 30.2 -KLHL22 FLJ14360, KELCHL ENSG00000099910 Kelch-like family member 22 22 20441519-20495883 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 34.9 -MED15 Arc105, CAG7A, PCQAP, TIG-1, TNRC7 ENSG00000099917 Mediator complex subunit 15 22 20495913-20587632 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003179 Approved Supported Nucleus Expressed in all spleen: 44.4 -SERPIND1 D22S673, HC-II, HC2, HCF2, HLS2 ENSG00000099937 Serpin peptidase inhibitor, clade D (heparin cofactor), member 1 22 20773879-20787720 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008639, HPA055767 Supported Approved Vesicles Tissue enriched 16 liver: 584.7 parathyroid gland: 35.5 -SNAP29 CEDNIK, SNAP-29 ENSG00000099940 Synaptosomal-associated protein, 29kDa 22 20858983-20891218 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031823, CAB037092, HPA056492 Supported Supported Nucleoplasm
Cytosol Expressed in all testis: 74.3 -CRKL ENSG00000099942 V-crk avian sarcoma virus CT10 oncogene homolog-like 22 20917426-20953749 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000532, HPA001100 Uncertain Validated Nucleoplasm
Cytosol Expressed in all cerebral cortex: 53.6 -LZTR1 BTBD29, LZTR-1 ENSG00000099949 Leucine-zipper-like transcription regulator 1 22 20979462-20999038 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068772, HPA071248 Approved Approved Nucleus Expressed in all parathyroid gland: 25.5 -MMP11 STMY3 ENSG00000099953 Matrix metallopeptidase 11 22 23768226-23784316 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB002593, HPA068864 Approved Group enriched 9 cervix, uterine: 30.9;endometrium: 122.3;placenta: 27.9 smooth muscle: 6.4 -CECR2 KIAA1740 ENSG00000099954 Cat eye syndrome chromosome region, candidate 2 22 17359949-17558149 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002943 Approved Approved Nucleus
Nucleoli Tissue enhanced 0 cerebral cortex: 7.8 skeletal muscle: 7.5 -SMARCB1 BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1 ENSG00000099956 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 22 23786963-23834516 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009196, HPA018248, HPA019127 Supported Supported Nucleoplasm
Nucleoli fibrillar center Expressed in all testis: 51.2 -P2RX6 MGC129625, P2RXL1, P2X6, P2XM ENSG00000099957 Purinergic receptor P2X, ligand gated ion channel, 6 22 21009808-21028830 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA028776, HPA028777 Approved Approved Nucleoli
Cytosol Tissue enhanced 0 cerebral cortex: 3.4 skeletal muscle: 3.0 -DERL3 C22orf14, derlin-3, FLJ43842, IZP6, MGC71803 ENSG00000099958 Derlin 3 22 23834503-23839128 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB037234, HPA049306 Uncertain Uncertain Vesicles Mixed stomach: 39.0 -SLC7A4 CAT-4, HCAT3, VH ENSG00000099960 Solute carrier family 7, member 4 22 21028718-21032840 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA031023 Approved Tissue enhanced 0 testis: 22.5 esophagus: 6.0 -BCL2L13 BCL-RAMBO, MIL1 ENSG00000099968 BCL2-like 13 (apoptosis facilitator) 22 17628855-17730855 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002052, HPA030994, HPA050377 Uncertain Supported Mitochondria Expressed in all parathyroid gland: 45.9 -DDTL ENSG00000099974 D-dopachrome tautomerase-like 22 23966901-23972532 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed liver: 6.5 -DDT DDCT ENSG00000099977 D-dopachrome tautomerase 22 23971365-23980469 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049871 Approved Approved Mitochondria Expressed in all liver: 109.2 -OSM MGC20461 ENSG00000099985 Oncostatin M 22 30262829-30266840 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 bone marrow: 78.8 appendix: 20.6 -CABIN1 KIAA0330, PPP3IN ENSG00000099991 Calcineurin binding protein 1 22 24011192-24178628 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043296 Approved Approved Nucleoplasm
Aggresome
Cytosol Expressed in all thyroid gland: 33.7 -TBC1D10A AC004997.C22.2, EPI64, TBC1D10 ENSG00000099992 TBC1 domain family, member 10A 22 30291990-30327046 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007725, HPA008142, HPA076041 Approved Supported Nucleoplasm
Plasma membrane Mixed esophagus: 31.3 -SUSD2 BK65A6.2, FLJ22778 ENSG00000099994 Sushi domain containing 2 22 24181259-24189110 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004117 Approved Approved Plasma membrane Tissue enhanced 0 lung: 139.6 small intestine: 35.8 -SF3A1 Prp21, PRPF21, SAP114, SF3a120 ENSG00000099995 Splicing factor 3a, subunit 1, 120kDa 22 30331988-30356947 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000690, HPA030083 Supported Validated Nuclear speckles Expressed in all testis: 88.7 -GGT5 GGT-REL, GGTLA1 ENSG00000099998 Gamma-glutamyltransferase 5 22 24219654-24245142 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008121, CAB032489 Uncertain Approved Nucleoli fibrillar center Mixed adipose tissue: 66.8 -RNF215 ENSG00000099999 Ring finger protein 215 22 30368811-30421771 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA019262, HPA056498 Approved Approved Nucleoli
Microtubules Expressed in all cerebral cortex: 19.3 -SEC14L2 C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1 ENSG00000100003 SEC14-like lipid binding 2 22 30396857-30425317 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064466 Approved Supported Nucleus
Cytosol Tissue enhanced 0 epididymis: 103.6;liver: 125.2;prostate: 82.7 breast: 56.6 -SEC14L3 TAP2 ENSG00000100012 SEC14-like lipid binding 3 22 30447959-30472049 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059450 Uncertain Tissue enhanced 0 bone marrow: 2.3;thyroid gland: 2.7 lung: 1.5 -SPECC1L CYTSA, KIAA0376 ENSG00000100014 Sperm antigen with calponin homology and coiled-coil domains 1-like 22 24270817-24417740 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070614 Uncertain Supported Actin filaments Expressed in all testis: 58.3 -PPIL2 CYC4, Cyp-60, UBOX7 ENSG00000100023 Peptidylprolyl isomerase (cyclophilin)-like 2 22 21652270-21700015 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035344, HPA055637 Supported Validated Nucleoplasm Expressed in all thyroid gland: 31.5 -UPB1 BUP1 ENSG00000100024 Ureidopropionase, beta 22 24494107-24528390 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000728 Supported Group enriched 24 kidney: 50.8;liver: 161.3 testis: 4.4 -YPEL1 ENSG00000100027 Yippee-like 1 22 21697544-21735834 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA030501, HPA045621 Uncertain Tissue enhanced 0 testis: 36.6 cerebral cortex: 16.2 -SNRPD3 Sm-D3, SMD3 ENSG00000100028 Small nuclear ribonucleoprotein D3 polypeptide 18kDa 22 24555503-24609980 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001170 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all thyroid gland: 77.8 -PES1 PES ENSG00000100029 Pescadillo ribosomal biogenesis factor 1 22 30576625-30607083 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040210, HPA062439, HPA066670 Supported Validated Nucleus
Nucleoli Expressed in all parathyroid gland: 49.4 -MAPK1 ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2 ENSG00000100030 Mitogen-activated protein kinase 1 22 21754500-21867680 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003995, CAB004229, HPA005700, HPA030069 Approved Expressed in all cerebral cortex: 132.8 -GGT1 CD224, D22S672, D22S732, GGT ENSG00000100031 Gamma-glutamyltransferase 1 22 24583750-24629005 Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045635, HPA047534, HPA065444 Supported Approved Vesicles Tissue enhanced 0 kidney: 160.6 small intestine: 97.9 -PRODH HSPOX2, PIG6, PRODH1, PRODH2, TP53I6 ENSG00000100033 Proline dehydrogenase (oxidase) 1 22 18912777-18936553 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020361 Uncertain Tissue enhanced 0 small intestine: 25.8 duodenum: 5.9 -PPM1F CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2 ENSG00000100034 Protein phosphatase, Mg2+/Mn2+ dependent, 1F 22 21919420-21952837 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030989, HPA030990 Approved Approved Nucleoplasm
Plasma membrane Expressed in all placenta: 39.4 -SLC35E4 ENSG00000100036 Solute carrier family 35, member E4 22 30635652-30669016 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049558 Approved Approved Cytosol Tissue enhanced 0 testis: 17.6 cerebral cortex: 5.1 -TOP3B ENSG00000100038 Topoisomerase (DNA) III beta 22 21957025-21982816 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069678 Approved Vesicles Mixed spleen: 19.3 -CRYBB3 CRYB3 ENSG00000100053 Crystallin, beta B3 22 25199850-25207363 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055840 Uncertain Mixed thyroid gland: 2.1 -CYTH4 CYT4, cytohesin-4, PSCD4 ENSG00000100055 Cytohesin 4 22 37282027-37315345 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA071573 Approved Tissue enhanced 0 appendix: 92.0 spleen: 71.0 -DGCR14 DGCR13, DGS-H, DGSI, ES2, Es2el ENSG00000100056 DiGeorge syndrome critical region gene 14 22 19130279-19144684 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001221, HPA001222 Supported Approved Nucleoplasm Mixed testis: 2.1 -MFNG ENSG00000100060 MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 22 37469063-37486401 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA048936, HPA056479 Approved Uncertain Actin filaments Mixed lymph node: 69.5 -CARD10 BIMP1, CARMA3 ENSG00000100065 Caspase recruitment domain family, member 10 22 37490362-37519542 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029359, HPA055612 Approved Approved Vesicles
Intermediate filaments
Cytosol Mixed small intestine: 40.7 -LRP5L DKFZp434O0213 ENSG00000100068 Low density lipoprotein receptor-related protein 5-like 22 25351418-25405377 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028717 Uncertain Approved Nucleoplasm Mixed thyroid gland: 9.7 -SLC25A1 CTP, SLC20A3 ENSG00000100075 Solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 22 19175575-19178830 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all duodenum: 115.9 -ADRBK2 BARK2, GRK3 ENSG00000100077 Adrenergic, beta, receptor kinase 2 22 25564849-25729294 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000804 Uncertain Approved Nucleus
Plasma membrane Mixed adipose tissue: 32.7 -PLA2G3 GIII-SPLA2 ENSG00000100078 Phospholipase A2, group III 22 31134809-31140607 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021016 Uncertain Tissue enhanced 0 esophagus: 4.4;lung: 3.6;skin: 10.3 tonsil: 1.5 -LGALS2 HL14 ENSG00000100079 Lectin, galactoside-binding, soluble, 2 22 37570246-37582616 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003536, CAB025198 Supported Approved Nucleoplasm
Mitochondria Tissue enhanced 0 gallbladder: 539.7;small intestine: 229.5 kidney: 154.8 -GGA1 ENSG00000100083 Golgi-associated, gamma adaptin ear containing, ARF binding protein 1 22 37608475-37633564 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048280, HPA051016 Supported Supported Nucleoplasm
Vesicles Expressed in all testis: 199.1 -HIRA DGCR1, TUP1, TUPLE1 ENSG00000100084 Histone cell cycle regulator 22 19330698-19447450 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB039243, CAB039244, HPA050714, HPA052902 Supported Validated Nucleoplasm Expressed in all thyroid gland: 93.6 -SH3BP1 ARHGAP43 ENSG00000100092 SH3-domain binding protein 1 22 37634654-37666932 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000757 Approved Approved Cytosol Mixed spleen: 18.3 -SEZ6L ENSG00000100095 Seizure related 6 homolog (mouse)-like 22 26169474-26383597 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 cerebral cortex: 89.4 adrenal gland: 13.7 -LGALS1 GBP ENSG00000100097 Lectin, galactoside-binding, soluble, 1 22 37675608-37679806 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000646, HPA000687, HPA001130, CAB002157 Approved Approved Nucleoplasm
Cytosol Expressed in all smooth muscle: 1705.8 -HPS4 BLOC3S2, KIAA1667, LE ENSG00000100099 Hermansky-Pudlak syndrome 4 22 26443423-26483837 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033106, HPA050189 Approved Approved Centrosome Expressed in all testis: 24.1 -PIK3IP1 HGFL, MGC17330 ENSG00000100100 Phosphoinositide-3-kinase interacting protein 1 22 31281593-31292534 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all lymph node: 122.7 -SRRD HC/HCC, SRR1L ENSG00000100104 SRR1 domain containing 22 26483877-26494658 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA002945 Uncertain Approved Cytosol Expressed in all thyroid gland: 29.9 -PATZ1 dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG ENSG00000100105 POZ (BTB) and AT hook containing zinc finger 1 22 31325804-31346232 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047893, HPA048315 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 39.8 -TRIOBP DFNB28, HRIHFB2122, KIAA1662, TAP68, Tara ENSG00000100106 TRIO and F-actin binding protein 22 37697004-37776556 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003747, HPA019769 Supported Uncertain Cytosol Expressed in all spleen: 67.1 -TFIP11 DKFZP434B194, Spp382, TIP39 ENSG00000100109 Tuftelin interacting protein 11 22 26491225-26512505 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027085 Approved Nucleoplasm
Cytosol Expressed in all testis: 50.8 -GCAT KBL ENSG00000100116 Glycine C-acetyltransferase 22 37807905-37817176 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020460 Uncertain Supported Nucleoplasm
Mitochondria Expressed in all pancreas: 28.9 -GGTLC2 GGTL4 ENSG00000100121 Gamma-glutamyltransferase light chain 2 22 22644475-22647903 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA045635, HPA047534 Uncertain Tissue enriched 9 testis: 7.1 small intestine: 0.7 -CRYBB1 ENSG00000100122 Crystallin, beta B1 22 26599278-26618088 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 epididymis: 10.9 placenta: 4.5 -ANKRD54 LIAR ENSG00000100124 Ankyrin repeat domain 54 22 37830855-37849327 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071287 Approved Approved Nucleoplasm
Microtubules
Midbody Expressed in all fallopian tube: 35.2 -EIF3L EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025 ENSG00000100129 Eukaryotic translation initiation factor 3, subunit L 22 37848868-37889407 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003028 Approved Approved Nucleus
Nucleoli Expressed in all breast: 179.6 -SNU13 15.5K, FA-1, NHP2L1, SNRNP15-5, SPAG12, SSFA1 ENSG00000100138 SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5) 22 41673930-41690504 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029199 Uncertain Expressed in all adrenal gland: 168.4 -MICALL1 KIAA1668, MICAL-L1, MIRAB13 ENSG00000100139 MICAL-like 1 22 37905657-37942822 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043480, HPA051956 Uncertain Supported Cell Junctions
Microtubule organizing center
Cytosol Expressed in all smooth muscle: 50.6 -POLR2F HRBP14.4, RPB6 ENSG00000100142 Polymerase (RNA) II (DNA directed) polypeptide F 22 37952607-38041915 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000827, CAB009882 Supported Validated Nucleus
Nucleoli fibrillar center Expressed in all cerebral cortex: 121.0 -SOX10 DOM, WS2E, WS4 ENSG00000100146 SRY (sex determining region Y)-box 10 22 37970686-37987422 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003171, HPA068898 Supported Supported Nucleoplasm Tissue enhanced 0 cerebral cortex: 56.8;salivary gland: 50.8 breast: 24.0 -CCDC134 FLJ22349 ENSG00000100147 Coiled-coil domain containing 134 22 41800679-41826299 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003936 Approved Mixed adrenal gland: 13.9 -DEPDC5 DEP.5, KIAA0645 ENSG00000100150 DEP domain containing 5 22 31753951-31907034 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054969, HPA055619 Uncertain Approved Golgi apparatus Mixed cerebral cortex: 13.5 -PICK1 dJ1039K5, MGC15204, PRKCABP ENSG00000100151 Protein interacting with PRKCA 1 22 38056311-38075701 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067384, HPA072674 Approved Approved Mitochondria
Cytosol Expressed in all parathyroid gland: 52.1 -TTC28 KIAA1043 ENSG00000100154 Tetratricopeptide repeat domain 28 22 27978014-28679865 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003099 Approved Nucleoli
Mitochondria Mixed ovary: 21.0 -SLC16A8 MCT3, REMP ENSG00000100156 Solute carrier family 16 (monocarboxylate transporter), member 8 22 38078134-38084093 Plasma proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA075017 Approved Intermediate filaments
Focal adhesion sites Mixed prostate: 5.7 -CENPM C22orf18, CENP-M, MGC861, Pane1 ENSG00000100162 Centromere protein M 22 41938721-41947164 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042404, HPA056500 Supported Validated Cytosol Tissue enhanced 0 lymph node: 28.9 bone marrow: 17.6 -SEPT3 SEP3 ENSG00000100167 Septin 3 22 41976272-41998221 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003548, CAB017633 Supported Approved Nucleoplasm
Plasma membrane
Actin filaments Tissue enriched 11 cerebral cortex: 235.5 parathyroid gland: 21.5 -SLC5A1 D22S675, NAGT, SGLT1 ENSG00000100170 Solute carrier family 5 (sodium/glucose cotransporter), member 1 22 32043032-32113029 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015467, HPA051805, HPA055106 Supported Approved Nucleoplasm
Vesicles Group enriched 10 duodenum: 518.9;small intestine: 320.2 gallbladder: 40.3 -SLC5A4 DJ90G24.4, SAAT1, SGLT3 ENSG00000100191 Solute carrier family 5 (glucose activated ion channel), member 4 22 32218476-32255341 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 9 duodenum: 18.5;small intestine: 21.8 lung: 2.3 -KDELR3 ENSG00000100196 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 22 38468062-38483447 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043477, HPA076405 Uncertain Validated Endoplasmic reticulum Mixed cervix: 46.3 -CYP2D6 CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D ENSG00000100197 Cytochrome P450, family 2, subfamily D, polypeptide 6 22 42126499-42130906 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045223 Supported Uncertain Golgi apparatus Tissue enhanced 0 liver: 11.4;small intestine: 13.2 duodenum: 3.9 -DDX17 P72 ENSG00000100201 DEAD (Asp-Glu-Ala-Asp) box helicase 17 22 38483440-38507660 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB024908, HPA063142 Supported Validated Nuclear speckles Expressed in all parathyroid gland: 328.9 -DMC1 LIM15 ENSG00000100206 DNA meiotic recombinase 1 22 38518949-38570286 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001232, CAB015397 Supported Approved Nucleoplasm Tissue enriched 5 testis: 22.0 endometrium: 4.0 -TCF20 AR1, SPBP ENSG00000100207 Transcription factor 20 (AR1) 22 42160013-42343616 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017849, HPA036786 Approved Supported Nucleoplasm
Nuclear bodies Mixed thyroid gland: 4.2 -HSCB DNAJC20, HSC20, Jac1 ENSG00000100209 HscB mitochondrial iron-sulfur cluster co-chaperone 22 28742031-28757515 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018447, HPA031518 Uncertain Supported Nucleus
Mitochondria
Cytosol Expressed in all adrenal gland: 13.3 -CBY1 C22orf2, Cby, Chibby, PGEA1, PIGEA-14, PIGEA14 ENSG00000100211 Chibby homolog 1 (Drosophila) 22 38656636-38673854 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all fallopian tube: 95.4 -TOMM22 TOM22 ENSG00000100216 Translocase of outer mitochondrial membrane 22 homolog (yeast) 22 38681948-38685421 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003037 Supported Validated Mitochondria Expressed in all fallopian tube: 32.4 -RSPH14 RTDR1 ENSG00000100218 Radial spoke head 14 homolog (Chlamydomonas) 22 23059415-23145021 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018420, HPA050425 Uncertain Uncertain Nucleoli Tissue enhanced 0 fallopian tube: 18.8;testis: 30.8 kidney: 7.5 -XBP1 XBP2 ENSG00000100219 X-box binding protein 1 22 28794555-28800597 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all breast: 907.4 -RTCB C22orf28, FAAP, HSPC117 ENSG00000100220 RNA 2',3'-cyclic phosphate and 5'-OH ligase 22 32387582-32412255 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000535, HPA001103 Supported Supported Nucleoplasm
Vesicles
Cytosol Expressed in all parathyroid gland: 102.3 -JOSD1 KIAA0063 ENSG00000100221 Josephin domain containing 1 22 38685543-38701556 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001168 Uncertain Expressed in all bone marrow: 56.5 -FBXO7 Fbx, FBX7, PARK15 ENSG00000100225 F-box protein 7 22 32474676-32498829 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032113, HPA032114, CAB034296 Uncertain Supported Nucleus
Cytosol Expressed in all thyroid gland: 223.9 -GTPBP1 GP-1, HSPC018 ENSG00000100226 GTP binding protein 1 22 38705723-38738299 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003166, HPA064702 Uncertain Approved Nuclear bodies
Golgi apparatus
Cytosol Expressed in all bone marrow: 65.1 -POLDIP3 KIAA1649, PDIP46 ENSG00000100227 Polymerase (DNA-directed), delta interacting protein 3 22 42583721-42614962 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018419, HPA048790 Approved Validated Nuclear speckles
Cytoplasmic bodies Expressed in all ovary: 109.4 -RAB36 ENSG00000100228 RAB36, member RAS oncogene family 22 23145326-23164350 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059631 Approved Vesicles Tissue enhanced 0 fallopian tube: 52.4;thyroid gland: 29.6 testis: 10.4 -TIMP3 SFD ENSG00000100234 TIMP metallopeptidase inhibitor 3 22 32801701-32863043 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 placenta: 1428.9 adipose tissue: 727.5 -PPP6R2 dJ579N16.1, KIAA0685, SAP190, SAPS2 ENSG00000100239 Protein phosphatase 6, regulatory subunit 2 22 50343304-50445090 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030656, CAB034919 Uncertain Supported Vesicles
Cytosol Expressed in all testis: 65.3 -SBF1 DENND7A, MTMR5 ENSG00000100241 SET binding factor 1 22 50445000-50475024 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065538 Approved Endoplasmic reticulum
Vesicles Expressed in all testis: 84.3 -SUN2 UNC84B ENSG00000100242 Sad1 and UNC84 domain containing 2 22 38734725-38794143 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001209 Supported Supported Nuclear membrane Expressed in all lymph node: 120.6 -CYB5R3 DIA1 ENSG00000100243 Cytochrome b5 reductase 3 22 42617840-42649568 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001566 Approved Validated Endoplasmic reticulum Expressed in all adipose tissue: 336.2 -DNAL4 dJ327J16, PIG27 ENSG00000100246 Dynein, axonemal, light chain 4 22 38778508-38794198 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003647 Approved Approved Nucleus
Nucleoli
Centrosome
Cytosol Expressed in all testis: 59.7 -C22orf31 bK747E2.1, HS747E2A ENSG00000100249 Chromosome 22 open reading frame 31 22 29058672-29061844 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000604 Uncertain Tissue enriched 12 testis: 13.9 epididymis: 1.1 -MIOX ALDRL6 ENSG00000100253 Myo-inositol oxygenase 22 50486784-50490648 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039451, HPA039562 Supported Tissue enriched 30 kidney: 818.9 thyroid gland: 26.8 -LMF2 TMEM112B, TMEM153 ENSG00000100258 Lipase maturation factor 2 22 50502949-50507691 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062626 Approved Approved Centrosome Expressed in all pancreas: 38.0 -RHBDD3 C22orf3, PTAG ENSG00000100263 Rhomboid domain containing 3 22 29259852-29268209 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043979 Approved Approved Microtubules Mixed testis: 10.5 -PACSIN2 SDPII ENSG00000100266 Protein kinase C and casein kinase substrate in neurons 2 22 42835412-43015145 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049854, HPA056520 Supported Supported Nuclear speckles
Vesicles
Plasma membrane
Cytosol Expressed in all adrenal gland: 95.8 -TTLL1 C22orf7 ENSG00000100271 Tubulin tyrosine ligase-like family member 1 22 43039644-43089428 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048392 Approved Approved Nucleoli
Mitochondria Mixed testis: 20.2 -RASL10A RRP22 ENSG00000100276 RAS-like, family 10, member A 22 29312933-29319679 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA056169 Approved Tissue enriched 15 cerebral cortex: 33.6 breast: 2.2 -AP1B1 ADTB1, AP105A, BAM22, CLAPB2 ENSG00000100280 Adaptor-related protein complex 1, beta 1 subunit 22 29327680-29423179 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065226, HPA068520 Approved Supported Golgi apparatus
Vesicles Expressed in all parathyroid gland: 102.2 -HMGXB4 HMG2L1, THC211630 ENSG00000100281 HMG box domain containing 4 22 35257452-35295807 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000725 Approved Expressed in all endometrium: 18.7 -TOM1 ENSG00000100284 Target of myb1 membrane trafficking protein 22 35299275-35347994 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000818, HPA001749 Approved Approved Plasma membrane
Microtubule organizing center
Cytosol Expressed in all esophagus: 54.8 -NEFH ENSG00000100285 Neurofilament, heavy polypeptide 22 29480230-29491390 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007786, HPA061615 Supported Approved Nucleus
Nuclear bodies
Centrosome Tissue enriched 13 prostate: 484.2 cerebral cortex: 37.4 -CHKB CHETK, CHKL ENSG00000100288 Choline kinase beta 22 50578949-50601455 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018797 Approved Approved Cytosol Mixed testis: 15.0 -BIK NBK ENSG00000100290 BCL2-interacting killer (apoptosis-inducing) 22 43110748-43129712 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051360 Approved Mixed lymph node: 14.2 -HMOX1 bK286B10, HO-1 ENSG00000100292 Heme oxygenase 1 22 35380361-35394214 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000635, CAB017444 Supported Uncertain Golgi apparatus
Plasma membrane Expressed in all spleen: 435.2 -MCAT fabD, FASN2C, MCT, MT, NET62 ENSG00000100294 Malonyl CoA:ACP acyltransferase (mitochondrial) 22 43132206-43143394 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003122, HPA035471 Approved Supported Mitochondria Expressed in all fallopian tube: 22.7 -THOC5 C22orf19, Fmip, fSAP79, KIAA0983, PK1.3 ENSG00000100296 THO complex 5 22 29505879-29555216 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048402 Supported Nucleoplasm Expressed in all smooth muscle: 42.7 -MCM5 CDC46 ENSG00000100297 Minichromosome maintenance complex component 5 22 35400063-35425430 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000101, HPA000845, HPA052880 Supported Validated Nucleoplasm Expressed in all bone marrow: 88.7 -APOBEC3H ARP10 ENSG00000100298 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 22 39097224-39104067 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA021492 Approved Mixed epididymis: 4.9 -ARSA ENSG00000100299 Arylsulfatase A 22 50622754-50628173 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005554, CAB025183 Supported Uncertain Golgi apparatus
Cytosol Expressed in all testis: 37.4 -TSPO BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS ENSG00000100300 Translocator protein (18kDa) 22 43151514-43163242 Cancer-related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011232, HPA046260 Uncertain Approved Vesicles
Mitochondria
Cytosol Expressed in all bone marrow: 301.2 -RASD2 MGC:4834, Rhes, TEM2 ENSG00000100302 RASD family, member 2 22 35540868-35554001 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA005839 Approved Approved Plasma membrane
Cytosol Tissue enhanced 0 seminal vesicle: 31.8 epididymis: 18.2 -TTLL12 KIAA0153 ENSG00000100304 Tubulin tyrosine ligase-like family member 12 22 43166622-43187133 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003054, CAB046029 Approved Approved Plasma membrane
Cytosol Expressed in all esophagus: 74.6 -CBX7 ENSG00000100307 Chromobox homolog 7 22 39120167-39152674 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011574, HPA048677, HPA056480 Supported Supported Nucleoplasm
Cytosol Expressed in all seminal vesicle: 80.8 -PDGFB SIS, SSV ENSG00000100311 Platelet-derived growth factor beta polypeptide 22 39223359-39244751 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011604, HPA011972, CAB018341 Supported Approved Vesicles Tissue enhanced 0 placenta: 59.5 lung: 28.7 -ACR ENSG00000100312 Acrosin 22 50738196-50745334 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048687 Supported Tissue enriched 56 testis: 115.9 spleen: 2.0 -CABP7 MGC57793 ENSG00000100314 Calcium binding protein 7 22 29720084-29731839 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA016439 Uncertain Tissue enhanced 0 adrenal gland: 2.5;cerebral cortex: 3.4 small intestine: 1.4 -RPL3 L3 ENSG00000100316 Ribosomal protein L3 22 39312882-39320389 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003365 Uncertain Supported Nucleoli
Cytosol Expressed in all ovary: 5662.0 -ZMAT5 SNRNP20, ZC3H19 ENSG00000100319 Zinc finger, matrin-type 5 22 29730956-29767011 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004858 Approved Supported Nucleoplasm Expressed in all fallopian tube: 35.1 -RBFOX2 FOX-2, HNRBP2, HRNBP2, RBM9 ENSG00000100320 RNA binding protein, fox-1 homolog (C. elegans) 2 22 35738736-36028425 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006240 Approved Supported Nucleoplasm Mixed endometrium: 107.9 -SYNGR1 ENSG00000100321 Synaptogyrin 1 22 39349925-39385588 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029673, CAB034277 Supported Supported Cytosol Expressed in all cerebral cortex: 175.9 -TAB1 MAP3K7IP1 ENSG00000100324 TGF-beta activated kinase 1/MAP3K7 binding protein 1 22 39399741-39437060 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032328, HPA039988, HPA057104 Approved Validated Nuclear speckles
Cytosol Expressed in all cerebral cortex: 23.2 -ASCC2 ASC1p100, DKFZp586O0223, FLJ21588 ENSG00000100325 Activating signal cointegrator 1 complex subunit 2 22 29788608-29838304 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001439 Uncertain Approved Nucleus
Focal adhesion sites
Cytosol Expressed in all testis: 45.9 -MTMR3 FYVE-DSP1, KIAA0371, ZFYVE10 ENSG00000100330 Myotubularin related protein 3 22 29883155-30030866 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034515, HPA034516, HPA061399 Uncertain Supported Nucleoplasm
Cytosol Expressed in all bone marrow: 52.4 -MIEF1 FLJ20232, MiD51, SMCR7L ENSG00000100335 Mitochondrial elongation factor 1 22 39499432-39518132 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061059 Approved Intermediate filaments
Mitochondria Expressed in all testis: 22.4 -APOL4 APOLIV ENSG00000100336 Apolipoprotein L, 4 22 36189124-36204840 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049797, HPA055435 Approved Supported Vesicles Tissue enhanced 0 prostate: 27.8 lung: 19.8 -PNPLA5 dJ388M5.4, GS2L ENSG00000100341 Patatin-like phospholipase domain containing 5 22 43879678-43892013 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA050409, HPA054211 Uncertain Tissue enhanced 0 epididymis: 2.1 cerebral cortex: 1.1 -APOL1 APOL ENSG00000100342 Apolipoprotein L, 1 22 36253010-36267530 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018885, CAB056156 Supported Expressed in all liver: 116.0 -PNPLA3 adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon ENSG00000100344 Patatin-like phospholipase domain containing 3 22 43923739-43964488 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058058 Approved Approved Nucleoli
Mitochondria
Cytosol Tissue enhanced 0 liver: 16.2 kidney: 4.7 -MYH9 DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA ENSG00000100345 Myosin, heavy chain 9, non-muscle 22 36281281-36388018 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001644, CAB015386 Supported Approved Plasma membrane
Actin filaments
Cytosol Expressed in all spleen: 313.7 -CACNA1I Cav3.3 ENSG00000100346 Calcium channel, voltage-dependent, T type, alpha 1I subunit 22 39570753-39689737 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 4.7;thyroid gland: 2.7 adrenal gland: 2.3 -SAMM50 CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W ENSG00000100347 SAMM50 sorting and assembly machinery component 22 43955421-44010531 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034537 Supported Validated Mitochondria Expressed in all parathyroid gland: 237.7 -TXN2 MT-TRX ENSG00000100348 Thioredoxin 2 22 36467036-36482030 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000994, CAB008681 Approved Validated Mitochondria Expressed in all adrenal gland: 145.4 -FOXRED2 FLJ23322 ENSG00000100350 FAD-dependent oxidoreductase domain containing 2 22 36487190-36507101 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031611, HPA031612 Approved Mixed cerebral cortex: 30.9 -GRAP2 GADS, GRBLG, GrbX, Grf40, Mona ENSG00000100351 GRB2-related adaptor protein 2 22 39901082-39973721 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005788, CAB022073 Supported Tissue enhanced 0 lymph node: 18.2 spleen: 13.1 -EIF3D eIF3-p66, eIF3-zeta, eIF3d, EIF3S7 ENSG00000100353 Eukaryotic translation initiation factor 3, subunit D 22 36510850-36529436 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045882, HPA063330, HPA066216 Approved Supported Cytosol Expressed in all fallopian tube: 253.4 -TNRC6B KIAA1093 ENSG00000100354 Trinucleotide repeat containing 6B 22 40044817-40335808 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003180 Approved Mixed testis: 27.6 -SGSM3 DJ1042K10.2, RabGAP-5, RABGAP5, RUSC3, RUTBC3 ENSG00000100359 Small G protein signaling modulator 3 22 40370591-40410289 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048980 Approved Supported Golgi apparatus Expressed in all stomach: 76.7 -IFT27 BBS19, RABL4, RAYL ENSG00000100360 Intraflagellar transport 27 22 36758202-36776256 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018418 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all fallopian tube: 56.6 -PVALB D22S749 ENSG00000100362 Parvalbumin 22 36800684-36819479 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002515, HPA048536 Supported Approved Nucleoplasm
Nucleoli
Cell Junctions Tissue enriched 12 parathyroid gland: 536.6 kidney: 43.1 -KIAA0930 bK268H5.C22.1, C22orf9 ENSG00000100364 KIAA0930 22 45190338-45240769 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038091 Uncertain Approved Nuclear membrane
Mitochondria Expressed in all cerebral cortex: 76.4 -NCF4 p40phox, SH3PXD4 ENSG00000100365 Neutrophil cytosolic factor 4, 40kDa 22 36860988-36878015 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010146, HPA036156, HPA057975 Supported Supported Cytosol Tissue enhanced 0 bone marrow: 120.1 appendix: 61.1 -CSF2RB CD131, IL3RB, IL5RB ENSG00000100368 Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 22 36913628-36940449 CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA078677 Uncertain Golgi apparatus Tissue enhanced 0 appendix: 92.0 tonsil: 59.3 -SLC25A17 PMP34 ENSG00000100372 Solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 22 40769630-40819399 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052708, HPA060972 Approved Supported Peroxisomes Expressed in all ovary: 24.0 -UPK3A UPK3 ENSG00000100373 Uroplakin 3A 22 45284982-45295874 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA018407, HPA018415 Supported Uncertain Nuclear membrane
Nuclear bodies Group enriched 7 parathyroid gland: 12.8;prostate: 33.5;skeletal muscle: 12.6;urinary bladder: 16.0 thyroid gland: 2.6 -FAM118A bK268H5.C22.4, C22orf8, FLJ20635 ENSG00000100376 Family with sequence similarity 118, member A 22 45308968-45341955 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003902 Uncertain Approved Intermediate filaments
Cytosol Expressed in all parathyroid gland: 75.3 -KCTD17 FLJ12242 ENSG00000100379 Potassium channel tetramerization domain containing 17 22 37051736-37063390 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018459 Uncertain Tissue enhanced 0 cerebral cortex: 56.1 testis: 35.3 -ST13 FAM10A1, HIP, HSPABP1, P48, SNC6 ENSG00000100380 Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 22 40824535-40857022 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043233, HPA046412, HPA047114, HPA047116 Supported Validated Cytosol Expressed in all ovary: 778.9 -IL2RB CD122, IL15RB ENSG00000100385 Interleukin 2 receptor, beta 22 37125838-37175054 Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062657 Supported Tissue enhanced 0 spleen: 68.3 placenta: 52.4 -RBX1 BA554C12.1, RNF75, ROC1 ENSG00000100387 Ring-box 1, E3 ubiquitin protein ligase 22 40951347-40973309 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003038 Uncertain Supported Nucleoplasm Expressed in all epididymis: 69.5 -EP300 KAT3B, p300 ENSG00000100393 E1A binding protein p300 22 41091786-41180079 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000146, HPA003128, HPA004112 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 45.3 -L3MBTL2 dJ756G23.3, DKFZP761I141, H-l(3)mbt-l ENSG00000100395 L(3)mbt-like 2 (Drosophila) 22 41205205-41231271 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000815 Approved Nucleoplasm Expressed in all fallopian tube: 30.2 -CHADL SLRR4B ENSG00000100399 Chondroadherin-like 22 41229510-41240934 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005696, HPA024654 Uncertain Tissue enhanced 0 cerebral cortex: 28.5 skin: 6.7 -RANGAP1 Fug1, KIAA1835, SD ENSG00000100401 Ran GTPase activating protein 1 22 41245611-41286251 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004293, HPA050110, HPA062034 Supported Validated Nuclear membrane
Vesicles
Cytosol Expressed in all testis: 205.5 -ZC3H7B DKFZp434K0920, FLJ13787, KIAA1031, RoXaN ENSG00000100403 Zinc finger CCCH-type containing 7B 22 41301522-41360147 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001784 Uncertain Uncertain Cytosol Expressed in all parathyroid gland: 80.2 -PHF5A bK223H9.2, INI, MGC1346, Rds3, SAP14b, SF3b14b, SF3B7 ENSG00000100410 PHD finger protein 5A 22 41459717-41468725 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028885 Supported Validated Nucleoplasm Expressed in all lymph node: 40.3 -ACO2 ACONM ENSG00000100412 Aconitase 2, mitochondrial 22 41469125-41528989 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001097 Supported Supported Mitochondria Expressed in all heart muscle: 306.9 -POLR3H KIAA1665, RPC8 ENSG00000100413 Polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) 22 41525804-41544606 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046787 Approved Supported Nucleoplasm
Vesicles
Centrosome Expressed in all cerebral cortex: 35.6 -TRMU FLJ10140, MTO2, TRMT ENSG00000100416 TRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 22 46330875-46357340 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035273, HPA043300 Uncertain Supported Nucleoplasm
Mitochondria Expressed in all parathyroid gland: 16.6 -PMM1 Sec53 ENSG00000100417 Phosphomannomutase 1 22 41576894-41589890 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030712 Uncertain Expressed in all ovary: 54.9 -DESI1 D15Wsu75e, FAM152B, PPPDE2 ENSG00000100418 Desumoylating isopeptidase 1 22 41598028-41621096 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053415 Approved Approved Cytokinetic bridge
Cytosol Expressed in all cerebral cortex: 29.6 -CERK dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4 ENSG00000100422 Ceramide kinase 22 46684411-46738261 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064699 Approved Vesicles Expressed in all small intestine: 35.0 -BRD1 BRL, BRPF2 ENSG00000100425 Bromodomain containing 1 22 49773283-49827512 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000807, HPA001063 Approved Supported Nuclear speckles Expressed in all testis: 58.6 -ZBED4 KIAA0637 ENSG00000100426 Zinc finger, BED-type containing 4 22 49853842-49890078 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045341 Approved Supported Nucleoplasm Expressed in all lymph node: 7.8 -MLC1 KIAA0027, LVM, MLC, VL ENSG00000100427 Megalencephalic leukoencephalopathy with subcortical cysts 1 22 50059391-50085902 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003040, HPA067533 Supported Tissue enriched 8 cerebral cortex: 181.4 bone marrow: 23.1 -HDAC10 DKFZP761B039 ENSG00000100429 Histone deacetylase 10 22 50245183-50251405 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045977, HPA056514 Supported Approved Nucleoli fibrillar center Mixed spleen: 9.9 -KCNK10 K2p10.1, PPP1R97, TREK-2, TREK2 ENSG00000100433 Potassium channel, two pore domain subfamily K, member 10 14 88180103-88326907 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030462 Approved Tissue enhanced 0 cerebral cortex: 5.6;duodenum: 5.3 small intestine: 2.8 -ABHD4 FLJ12816 ENSG00000100439 Abhydrolase domain containing 4 14 22598237-22613215 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000600 Uncertain Approved Nucleus Expressed in all testis: 62.6 -KHNYN KIAA0323 ENSG00000100441 KH and NYN domain containing 14 24429286-24441834 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003402 Uncertain Approved Nucleoplasm
Cytosol Expressed in all placenta: 48.7 -FKBP3 FKBP-25, PPIase ENSG00000100442 FK506 binding protein 3, 25kDa 14 45115600-45135319 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000864, CAB012232, CAB012520 Supported Supported Cytosol Expressed in all skeletal muscle: 143.3 -SDR39U1 C14orf124, HCDI ENSG00000100445 Short chain dehydrogenase/reductase family 39U, member 1 14 24439766-24442905 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044294 Approved Approved Nucleoplasm
Cytosol Expressed in all adrenal gland: 43.0 -CTSG CG ENSG00000100448 Cathepsin G 14 24573522-24576260 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000110, HPA047737 Supported Tissue enriched 83 bone marrow: 3465.6 gallbladder: 41.5 -GZMH CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2 ENSG00000100450 Granzyme H (cathepsin G-like 2, protein h-CCPX) 14 24606480-24609699 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029200 Supported Tissue enhanced 0 spleen: 35.8 lymph node: 25.9 -GZMB CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT ENSG00000100453 Granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 14 24630954-24634267 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000376, HPA003418 Supported Tissue enhanced 0 lymph node: 40.7 spleen: 36.7 -RBM23 CAPERbeta, FLJ10482, RNPC4 ENSG00000100461 RNA binding motif protein 23 14 22893206-22919184 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004144 Uncertain Approved Nucleoplasm
Intermediate filaments Expressed in all parathyroid gland: 142.6 -PRMT5 HRMT1L5, SKB1, SKB1Hs ENSG00000100462 Protein arginine methyltransferase 5 14 22920511-22929585 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005525, CAB012459, HPA064708 Approved Approved Nucleus
Cytosol Expressed in all parathyroid gland: 71.4 -COCH COCH-5B2, DFNA31, DFNA9 ENSG00000100473 Cochlin 14 30874514-30895065 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065086 Approved Vesicles Group enriched 6 pancreas: 94.7;prostate: 86.5;seminal vesicle: 98.0 cervix: 15.4 -AP4S1 AP47B, CLA20, SPG52 ENSG00000100478 Adaptor-related protein complex 4, sigma 1 subunit 14 31025106-31096450 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039963 Approved Expressed in all testis: 33.2 -POLE2 DPE2 ENSG00000100479 Polymerase (DNA directed), epsilon 2, accessory subunit 14 49643555-49688422 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027555 Uncertain Supported Nucleoplasm
Nuclear bodies
Vesicles Mixed bone marrow: 10.8 -VCPKMT C14orf138, METTL21D, VCP-KMT ENSG00000100483 Valosin containing protein lysine (K) methyltransferase 14 50108632-50116600 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001146 Uncertain Mixed endometrium: 5.3 -SOS2 ENSG00000100485 Son of sevenless homolog 2 (Drosophila) 14 50117120-50231558 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004577, HPA047368, HPA052689 Approved Approved Nucleoplasm
Vesicles Expressed in all parathyroid gland: 79.3 -CDKL1 KKIALRE ENSG00000100490 Cyclin-dependent kinase-like 1 (CDC2-related kinase) 14 50329404-50416461 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059605, HPA065919 Uncertain Validated Nucleoplasm
Vesicles Mixed fallopian tube: 33.1 -NIN ENSG00000100503 Ninein (GSK3B interacting protein) 14 50719763-50831121 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005939, HPA070691 Supported Validated Nucleus
Nucleoli
Centrosome Mixed lymph node: 48.1 -PYGL ENSG00000100504 Phosphorylase, glycogen, liver 14 50857891-50944736 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000962, HPA004119 Supported Supported Plasma membrane
Cytosol Mixed adipose tissue: 116.1 -TRIM9 RNF91, SPRING ENSG00000100505 Tripartite motif containing 9 14 50975262-51096061 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041489 Supported Cytosol Tissue enriched 11 cerebral cortex: 79.4 gallbladder: 6.9 -PSMC6 p42 ENSG00000100519 Proteasome 26S subunit, ATPase 6 14 52707172-52728587 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042823 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all thyroid gland: 91.4 -GNPNAT1 FLJ10607, Gpnat1 ENSG00000100522 Glucosamine-phosphate N-acetyltransferase 1 14 52775194-52791668 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044647 Approved Expressed in all liver: 39.5 -DDHD1 KIAA1705, PA-PLA1, SPG28 ENSG00000100523 DDHD domain containing 1 14 53036745-53153282 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049870 Approved Tissue enhanced 0 testis: 34.0 cerebral cortex: 10.6 -CDKN3 CDI1, KAP ENSG00000100526 Cyclin-dependent kinase inhibitor 3 14 54396849-54420218 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005285, HPA039311, HPA058874 Validated Cytosol Tissue enriched 11 testis: 340.0 lymph node: 32.1 -CNIH1 CNIH, CNIL, TGAM77 ENSG00000100528 Cornichon family AMPA receptor auxiliary protein 1 14 54423560-54441431 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002544 Approved Approved Vesicles Expressed in all liver: 118.5 -CGRRF1 CGR19, RNF197 ENSG00000100532 Cell growth regulator with ring finger domain 1 14 54509812-54539309 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA002930 Uncertain Supported Nucleoplasm
Vesicles Expressed in all testis: 33.6 -ATP6V1D ATP6M, VATD, VMA8 ENSG00000100554 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 14 67294371-67360265 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031515, HPA057316 Supported Approved Nucleoplasm Expressed in all cerebral cortex: 196.2 -C14orf105 FLJ10650 ENSG00000100557 Chromosome 14 open reading frame 105 14 57469301-57493867 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029202 Uncertain Nucleus
Cytosol Tissue enhanced 0 fallopian tube: 43.3;gallbladder: 27.2;kidney: 63.2 liver: 11.3 -PLEK2 ENSG00000100558 Pleckstrin 2 14 67386983-67412200 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001208 Approved Uncertain Vesicles
Cytosol Mixed adrenal gland: 43.3 -PIGH GPI-H ENSG00000100564 Phosphatidylinositol glycan anchor biosynthesis, class H 14 67581955-67600287 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031624 Approved Expressed in all parathyroid gland: 105.5 -LRRC74A C14orf166B, LRRC74 ENSG00000100565 Leucine rich repeat containing 74A 14 76826372-76870302 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035094 Uncertain Tissue enriched 17 testis: 7.0 spleen: 0.4 -PSMA3 HC8 ENSG00000100567 Proteasome subunit alpha 3 14 58244831-58272012 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000905 Approved Expressed in all epididymis: 149.3 -VTI1B VTI2 ENSG00000100568 Vesicle transport through interaction with t-SNAREs 1B 14 67647075-67674831 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044121, HPA048150, HPA060118 Approved Validated Golgi apparatus
Vesicles Expressed in all epididymis: 62.3 -TIMM9 TIM9A ENSG00000100575 Translocase of inner mitochondrial membrane 9 homolog (yeast) 14 58408494-58427614 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002932 Approved Validated Mitochondria Expressed in all thyroid gland: 48.2 -GSTZ1 GSTZ1-1, MAAI, MAI ENSG00000100577 Glutathione S-transferase zeta 1 14 77320884-77331597 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004701 Approved Approved Nucleus
Cytosol Expressed in all liver: 133.9 -KIAA0586 JBTS23, Talpid3 ENSG00000100578 KIAA0586 14 58427385-58551289 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000846, HPA050249 Uncertain Approved Nucleoplasm
Cytosol Mixed testis: 29.2 -TMED8 FAM15B ENSG00000100580 Transmembrane p24 trafficking protein family member 8 14 77335021-77377109 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001205 Approved Mixed lymph node: 21.0 -SAMD15 C14orf174, FAM15A, FLJ35963 ENSG00000100583 Sterile alpha motif domain containing 15 14 77376689-77391497 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA030673, HPA030677 Approved Approved Nucleus
Nuclear membrane
Nucleoli Tissue enhanced 0 testis: 31.9 fallopian tube: 7.3 -AHSA1 Aha1, C14orf3, p38 ENSG00000100591 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 14 77457870-77469474 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000903, CAB006244 Supported Supported Cytosol Expressed in all fallopian tube: 178.7 -DAAM1 KIAA0666 ENSG00000100592 Dishevelled associated activator of morphogenesis 1 14 59188646-59371405 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026605, HPA064789 Uncertain Approved Plasma membrane
Cytosol Expressed in all parathyroid gland: 51.1 -ISM2 FLJ32147, TAIL1, THSD3 ENSG00000100593 Isthmin 2 14 77474394-77498850 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039314, HPA039742 Supported Supported Nucleoplasm Tissue enriched 114 placenta: 272.7 epididymis: 2.3 -SPTLC2 hLCB2a, KIAA0526, LCB2, LCB2A ENSG00000100596 Serine palmitoyltransferase, long chain base subunit 2 14 77505997-77616773 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027552 Approved Mitochondria Expressed in all placenta: 29.0 -RIN3 FLJ22439 ENSG00000100599 Ras and Rab interactor 3 14 92513774-92688994 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039836 Uncertain Mixed spleen: 29.8 -LGMN LGMN1, PRSC1 ENSG00000100600 Legumain 14 92703807-92748702 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000799, HPA001426 Supported Approved Cytosol Expressed in all placenta: 357.3 -ALKBH1 ABH, alkB, ALKBH, hABH ENSG00000100601 AlkB homolog 1, histone H2A dioxygenase 14 77672404-77708020 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044087 Approved Mixed placenta: 5.6 -SNW1 Bx42, NCoA-62, Prp45, PRPF45, SKIIP, SKIP ENSG00000100603 SNW domain containing 1 14 77717599-77761207 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002457, CAB009931, HPA017370 Supported Validated Nucleoplasm Expressed in all testis: 84.7 -CHGA ENSG00000100604 Chromogranin A 14 92923080-92935293 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000023, HPA017369, CAB040544, CAB055506, CAB058688 Supported Approved Vesicles Tissue enriched 8 parathyroid gland: 6987.1 adrenal gland: 822.0 -ITPK1 ENSG00000100605 Inositol-tetrakisphosphate 1-kinase 14 92936914-93116320 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055230 Approved Approved Mitochondria Expressed in all cerebral cortex: 93.4 -DHRS7 retDSR4, SDR34C1 ENSG00000100612 Dehydrogenase/reductase (SDR family) member 7 14 60144120-60169856 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031121 Approved Approved Nucleoplasm
Mitochondria Expressed in all prostate: 656.8 -PPM1A MGC9201, PP2CA, PP2Calpha ENSG00000100614 Protein phosphatase, Mg2+/Mn2+ dependent, 1A 14 60245752-60299087 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029209 Approved Supported Plasma membrane
Cytosol Expressed in all testis: 99.7 -SIX4 AREC3 ENSG00000100625 SIX homeobox 4 14 60709528-60724348 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031794 Uncertain Approved Nucleoplasm Tissue enhanced 0 parathyroid gland: 23.5 skeletal muscle: 4.7 -GALNT16 GalNAc-T16, GALNTL1, KIAA1130 ENSG00000100626 Polypeptide N-acetylgalactosaminyltransferase 16 14 69259277-69357033 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059136 Approved Approved Nucleus Mixed cerebral cortex: 28.6 -ASB2 ASB-2 ENSG00000100628 Ankyrin repeat and SOCS box containing 2 14 93934153-93976791 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skeletal muscle: 85.9 smooth muscle: 25.3 -CEP128 C14orf145, C14orf61 ENSG00000100629 Centrosomal protein 128kDa 14 80476983-80959517 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000602, HPA001116, HPA018498 Uncertain Supported Microtubule organizing center Mixed testis: 9.3 -ERH DROER ENSG00000100632 Enhancer of rudimentary homolog (Drosophila) 14 69380123-69398627 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002567 Approved Approved Nucleoplasm
Cytosol Expressed in all endometrium: 111.5 -HIF1A bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8 ENSG00000100644 Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 14 61695513-61748259 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000907, HPA001275, CAB017442 Supported Supported Nucleoplasm
Nuclear bodies
Plasma membrane Expressed in all bone marrow: 292.9 -SUSD6 KIAA0247 ENSG00000100647 Sushi domain containing 6 14 69611596-69715142 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030464 Uncertain Approved Nucleoplasm
Intermediate filaments Expressed in all epididymis: 51.6 -SRSF5 HRS, SFRS5, SRP40 ENSG00000100650 Serine/arginine-rich splicing factor 5 14 69726900-69772005 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043484, HPA056523 Approved Validated Nucleus
Nucleoli Expressed in all fallopian tube: 313.9 -SLC10A1 NTCP ENSG00000100652 Solute carrier family 10 (sodium/bile acid cotransporter), member 1 14 69775417-69797289 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042727 Approved Tissue enriched 392 liver: 212.1 gallbladder: 0.5 -EIF5 ENSG00000100664 Eukaryotic translation initiation factor 5 14 103333544-103345025 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000867, CAB004226 Supported Supported Plasma membrane
Cytosol Expressed in all testis: 173.0 -SERPINA4 KAL, kallistatin, KLST, KST, PI4 ENSG00000100665 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 14 94561091-94569913 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003607 Approved Tissue enhanced 0 gallbladder: 72.9;liver: 242.4 epididymis: 42.1 -SLC8A3 NCX3 ENSG00000100678 Solute carrier family 8 (sodium/calcium exchanger), member 3 14 70044217-70189070 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 cerebral cortex: 16.3;skeletal muscle: 6.1 adrenal gland: 1.7 -DICER1 Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1 ENSG00000100697 Dicer 1, ribonuclease type III 14 95086228-95158010 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000694, CAB068185 Approved Supported Cytosol Expressed in all placenta: 32.2 -ZFYVE21 MGC2550, ZF21 ENSG00000100711 Zinc finger, FYVE domain containing 21 14 103715730-103733668 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055721 Uncertain Expressed in all endometrium: 88.3 -MTHFD1 MTHFC, MTHFD ENSG00000100714 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 14 64388031-64463457 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000704, HPA001290, HPA015006, HPA050052 Approved Validated Cytosol Expressed in all liver: 198.3 -TCL1A TCL1 ENSG00000100721 T-cell leukemia/lymphoma 1A 14 95709967-95714196 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004045, HPA016604 Supported Tissue enhanced 0 lymph node: 328.5;tonsil: 204.6 spleen: 79.4 -ZC3H14 FLJ11806, NY-REN-37, UKp68 ENSG00000100722 Zinc finger CCCH-type containing 14 14 88562909-88627596 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049798, HPA053510 Supported Validated Nuclear speckles Expressed in all testis: 325.8 -TELO2 hCLK2, KIAA0683, TEL2 ENSG00000100726 Telomere maintenance 2 16 1493344-1510457 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041348, HPA041473 Approved Supported Nuclear bodies
Cytosol Expressed in all spleen: 15.8 -PCNX KIAA0805, KIAA0995, PCNXL1, pecanex ENSG00000100731 Pecanex homolog (Drosophila) 14 70907405-71115382 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053532 Approved Nucleoplasm Expressed in all testis: 38.1 -BDKRB1 B1BKR, BKR1, bradyb1 ENSG00000100739 Bradykinin receptor B1 14 96255824-96268967 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA002935 Approved Tissue enhanced 0 gallbladder: 18.3;urinary bladder: 10.3 appendix: 7.0 -GSKIP C14orf129 ENSG00000100744 GSK3B interacting protein 14 96363452-96387288 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043054, HPA046782 Approved Approved Nucleoli
Golgi apparatus
Vesicles Expressed in all small intestine: 63.2 -VRK1 ENSG00000100749 Vaccinia related kinase 1 14 96797304-96931722 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000660, HPA017929 Approved Supported Nucleus
Cytosol Mixed testis: 59.5 -PSMC1 p56, S4 ENSG00000100764 Proteasome 26S subunit, ATPase 1 14 90256495-90275429 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000872 Approved Validated Nucleoplasm
Cytosol Expressed in all testis: 139.5 -PAPLN MGC50452 ENSG00000100767 Papilin, proteoglycan-like sulfated glycoprotein 14 73237497-73274640 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048682, HPA053453 Uncertain Approved Nucleoplasm Mixed spleen: 21.0 -RPS6KA5 MSK1, RLPK ENSG00000100784 Ribosomal protein S6 kinase, 90kDa, polypeptide 5 14 90847862-91060636 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001274, HPA001780, CAB025458 Approved Validated Nucleoplasm Mixed breast: 13.0 -PPP4R3A FLFL1, FLJ20707, KIAA2010, MSTP033, PP4R3, SMEK1, smk-1, smk1 ENSG00000100796 Protein phosphatase 4, regulatory subunit 3A 14 91457611-91510554 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002568, HPA063917 Approved Supported Nucleoplasm Expressed in all testis: 61.0 -C14orf93 FLJ12154 ENSG00000100802 Chromosome 14 open reading frame 93 14 22985908-23010166 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002569 Approved Approved Nucleus
Plasma membrane Expressed in all skin: 21.7 -PSMB5 MB1, X ENSG00000100804 Proteasome subunit beta 5 14 23016543-23035230 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049518, HPA061796 Approved Supported Nucleus
Centrosome Expressed in all epididymis: 139.6 -YY1 DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1 ENSG00000100811 YY1 transcription factor 14 100238298-100282792 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001119, CAB009392 Supported Supported Nucleoplasm
Nucleoli fibrillar center
Vesicles Expressed in all thyroid gland: 65.8 -ACIN1 ACINUS, fSAP152, KIAA0670 ENSG00000100813 Apoptotic chromatin condensation inducer 1 14 23058564-23095614 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000657 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 76.7 -CCNB1IP1 C14orf18, HEI10 ENSG00000100814 Cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 14 20311368-20333312 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 120.3 -TRIP11 CEV14, GMAP-210, GMAP210, Trip230 ENSG00000100815 Thyroid hormone receptor interactor 11 14 91965991-92040896 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002570, HPA070684 Supported Validated Nucleus
Golgi apparatus Expressed in all parathyroid gland: 37.7 -APEX1 APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1 ENSG00000100823 APEX nuclease (multifunctional DNA repair enzyme) 1 14 20455191-20457772 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000956, HPA002564, CAB004294, CAB047307 Supported Validated Nucleus Expressed in all ovary: 176.0 -PABPN1 OPMD, PAB2, PABP2 ENSG00000100836 Poly(A) binding protein, nuclear 1 14 23321289-23326185 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000637 Supported Approved Expressed in all testis: 204.8 -EFS CASS3, EFS1, EFS2, HEFS, SIN ENSG00000100842 Embryonal Fyn-associated substrate 14 23356402-23365752 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001581, HPA001790 Approved Uncertain Nucleoplasm
Cytosol Mixed skin: 59.5 -ARHGAP5 GFI2, p190-B, p190BRhoGAP, RhoGAP5 ENSG00000100852 Rho GTPase activating protein 5 14 32076114-32159728 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046993, HPA056507 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all thyroid gland: 117.3 -CINP MGC849 ENSG00000100865 Cyclin-dependent kinase 2 interacting protein 14 102341102-102362916 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 47.9 -DHRS2 HEP27, SDR25C1 ENSG00000100867 Dehydrogenase/reductase (SDR family) member 2 14 23630115-23645639 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053915, HPA069551 Approved Validated Nucleus
Mitochondria Group enriched 9 breast: 427.4;urinary bladder: 351.8 salivary gland: 41.0 -SRP54 ENSG00000100883 Signal recognition particle 54kDa 14 34981957-35029567 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048977, HPA062044 Approved Supported Nucleoli
Cytosol Expressed in all testis: 89.5 -CPNE6 ENSG00000100884 Copine VI (neuronal) 14 24070837-24078100 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031636 Approved Group enriched 6 cerebral cortex: 88.2;seminal vesicle: 34.7 kidney: 9.6 -CHD8 DUPLIN, HELSNF1, KIAA1564 ENSG00000100888 Chromodomain helicase DNA binding protein 8 14 21385194-21456126 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052186 Supported Nucleoplasm Expressed in all parathyroid gland: 46.2 -PCK2 PEPCK, PEPCK2 ENSG00000100889 Phosphoenolpyruvate carboxykinase 2 (mitochondrial) 14 24094053-24110598 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018734, HPA051162, HPA053502 Supported Validated Mitochondria Group enriched 6 duodenum: 377.7;kidney: 191.6;liver: 258.5;small intestine: 282.4 colon: 47.9 -KIAA0391 MRPP3, PRORP ENSG00000100890 KIAA0391 14 35121846-35277614 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020459 Approved Supported Nucleus
Mitochondria Expressed in all parathyroid gland: 42.5 -DCAF11 GL014, PRO2389, WDR23 ENSG00000100897 DDB1 and CUL4 associated factor 11 14 24114195-24125242 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003583, HPA031157 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 73.0 -PSMA6 IOTA, MGC22756, MGC2333, MGC23846, p27K, PROS27 ENSG00000100902 Proteasome subunit alpha 6 14 35278633-35317493 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003049 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 387.7 -NFKBIA IkappaBalpha, IKBA, MAD-3, NFKBI ENSG00000100906 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 14 35401511-35404749 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003815, HPA029207 Approved Validated Cytosol Expressed in all bone marrow: 713.0 -EMC9 C14orf122, CGI-112, FAM158A ENSG00000100908 ER membrane protein complex subunit 9 14 24138959-24141588 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054715 Approved Golgi apparatus Expressed in all adrenal gland: 21.4 -PSME2 PA28beta ENSG00000100911 Proteasome activator subunit 2 14 24143362-24147570 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062661 Approved Nucleus Expressed in all duodenum: 296.0 -BRMS1L BRMS1, FLJ39177, MGC11296 ENSG00000100916 Breast cancer metastasis-suppressor 1-like 14 35826318-35932325 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046623 Uncertain Supported Nucleoplasm Mixed cerebral cortex: 24.6 -REC8 kleisin-alpha, REC8L1, Rec8p ENSG00000100918 REC8 meiotic recombination protein 14 24171853-24180257 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031727, HPA031729 Approved Approved Nucleoplasm Tissue enhanced 0 fallopian tube: 36.9 testis: 28.8 -TM9SF1 HMP70, MP70 ENSG00000100926 Transmembrane 9 superfamily member 1 14 24189143-24195687 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA059249 Supported Approved Golgi apparatus Expressed in all parathyroid gland: 71.2 -SEC23A ENSG00000100934 Sec23 homolog A, COPII coat complex component 14 39031919-39109646 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043806, HPA069974 Uncertain Approved Nucleoplasm
Vesicles Expressed in all smooth muscle: 139.3 -GMPR2 ENSG00000100938 Guanosine monophosphate reductase 2 14 24232422-24239242 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000904, HPA067884, HPA068782 Uncertain Approved Nucleoplasm
Nucleoli Expressed in all parathyroid gland: 217.9 -PNN memA ENSG00000100941 Pinin, desmosome associated protein 14 39175183-39183218 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001378 Supported Validated Nuclear speckles Expressed in all epididymis: 141.4 -RABGGTA PTAR3 ENSG00000100949 Rab geranylgeranyltransferase, alpha subunit 14 24265538-24271739 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043488 Approved Validated Nucleoplasm Expressed in all esophagus: 34.2 -NFATC4 NFAT3 ENSG00000100968 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 14 24365673-24379604 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031641, CAB032859, HPA076526 Uncertain Supported Nuclear speckles
Cytosol Mixed endometrium: 75.4 -PLTP BPIFE ENSG00000100979 Phospholipid transfer protein 20 45898621-45912155 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB032873 Approved Expressed in all placenta: 630.8 -PCIF1 bA465L10.1, C20orf67, PPP1R121 ENSG00000100982 PDX1 C-terminal inhibiting factor 1 20 45934628-45948023 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049517 Supported Supported Nucleoplasm
Microtubules
Cytokinetic bridge Expressed in all fallopian tube: 48.6 -GSS ENSG00000100983 Glutathione synthetase 20 34928430-34955817 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054508, HPA059315 Supported Supported Nucleus Expressed in all epididymis: 104.1 -MMP9 CLG4B ENSG00000100985 Matrix metallopeptidase 9 20 46008908-46016561 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201 Supported Approved Cytosol Tissue enhanced 0 bone marrow: 253.0;lymph node: 119.4 appendix: 85.4 -VSX1 PPCD, PPCD1, PPD ENSG00000100987 Visual system homeobox 1 20 25070885-25082365 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed ovary: 1.7 -TRPC4AP C20orf188, dJ756N5.2, DKFZp586C1223, DKFZP727M231, PPP1R158, TRRP4AP ENSG00000100991 Transient receptor potential cation channel, subfamily C, member 4 associated protein 20 35002404-35092871 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051197, HPA065061 Uncertain Approved Cytosol Expressed in all parathyroid gland: 71.2 -PYGB ENSG00000100994 Phosphorylase, glycogen; brain 20 25248069-25298014 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031067 Approved Approved Cytosol Expressed in all seminal vesicle: 148.6 -ABHD12 ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106 ENSG00000100997 Abhydrolase domain containing 12 20 25294743-25390983 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026866 Uncertain Expressed in all epididymis: 135.4 -PROCR CCD41, CD201, EPCR ENSG00000101000 Protein C receptor, endothelial 20 35172073-35216240 Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039461 Supported Expressed in all adipose tissue: 62.7 -GINS1 KIAA0186, PSF1 ENSG00000101003 GINS complex subunit 1 (Psf1 homolog) 20 25407727-25452628 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051185 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 14.7 lymph node: 6.6 -NINL KIAA0980, NLP ENSG00000101004 Ninein-like 20 25452705-25585517 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000686 Uncertain Approved Cytokinetic bridge
Cytosol Mixed parathyroid gland: 17.6 -CD40 Bp50, p50, TNFRSF5 ENSG00000101017 CD40 molecule, TNF receptor superfamily member 5 20 46118272-46129863 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002495, HPA031567, HPA031568, CAB072868 Supported Expressed in all lymph node: 65.6 -UQCC1 BFZB, C20orf44, CBP3, FLJ10850, UQCC ENSG00000101019 Ubiquinol-cytochrome c reductase complex assembly factor 1 20 35302566-35412141 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034875 Approved Approved Nucleoplasm
Plasma membrane
Actin filaments Expressed in all parathyroid gland: 42.6 -ZMYND8 PRKCBP1, RACK7 ENSG00000101040 Zinc finger, MYND-type containing 8 20 47209214-47356889 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020949 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all epididymis: 39.8 -SGK2 ENSG00000101049 Serum/glucocorticoid regulated kinase 2 20 43558968-43588237 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008859, HPA011387 Uncertain Supported Nucleoplasm Mixed kidney: 42.9 -IFT52 C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5 ENSG00000101052 Intraflagellar transport 52 20 43590931-43647296 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA063367, HPA067423 Supported Approved Cytosol Expressed in all fallopian tube: 60.6 -MYBL2 B-MYB, BMYB ENSG00000101057 V-myb avian myeloblastosis viral oncogene homolog-like 2 20 43667019-43716496 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017114, HPA030530, HPA055416 Uncertain Validated Nucleoplasm
Cytosol Tissue enhanced 0 bone marrow: 57.1;lymph node: 68.1;tonsil: 51.7 appendix: 33.8 -R3HDML dJ881L22.3 ENSG00000101074 R3H domain containing-like 20 44336986-44351235 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA070264 Supported Tissue enhanced 0 fallopian tube: 4.4;rectum: 6.2 small intestine: 2.8 -HNF4A HNF4, MODY, MODY1, NR2A1, TCF14 ENSG00000101076 Hepatocyte nuclear factor 4, alpha 20 44355700-44434596 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004712, CAB019417 Supported Supported Nucleoplasm Group enriched 7 colon: 58.9;duodenum: 105.9;kidney: 44.3;liver: 50.9;rectum: 48.5;small intestine: 92.8;stomach: 22.1 gallbladder: 9.2 -NDRG3 ENSG00000101079 NDRG family member 3 20 36651766-36746078 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017851, HPA018256 Approved Expressed in all cerebral cortex: 124.8 -SLA2 C20orf156, FLJ21992, SLAP-2 ENSG00000101082 Src-like-adaptor 2 20 36612318-36646216 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053746, HPA058217 Approved Nucleoplasm
Golgi apparatus
Vesicles Mixed lymph node: 11.9 -C20orf24 PNAS-11, RIP5 ENSG00000101084 Chromosome 20 open reading frame 24 20 36605734-36612557 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057387 Uncertain Approved Cytosol Expressed in all esophagus: 83.3 -NFATC2 NF-ATP, NFAT1, NFATp ENSG00000101096 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 20 51386957-51562831 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008789, CAB018567, HPA024369 Supported Supported Nucleoplasm
Cytosol Expressed in all gallbladder: 26.8 -RIMS4 C20orf190, dJ781B1.3 ENSG00000101098 Regulating synaptic membrane exocytosis 4 20 44751808-44810338 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060928 Approved Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 27.4;testis: 20.3 fallopian tube: 13.2 -PABPC1L C20orf119, dJ1069P2.3, ePAB, PABPC1L1 ENSG00000101104 Poly(A) binding protein, cytoplasmic 1-like 20 44910062-44959035 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA066650 Approved Nuclear bodies
Cytosol Mixed thyroid gland: 54.0 -STK4 KRS2, MST1, YSK3 ENSG00000101109 Serine/threonine kinase 4 20 44966474-45079959 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004038, HPA015270 Approved Validated Nucleoplasm
Nuclear bodies
Cytosol Expressed in all lymph node: 51.4 -SALL4 dJ1112F19.1, ZNF797 ENSG00000101115 Spalt-like transcription factor 4 20 51782331-51802520 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015291, HPA015791 Supported Validated Nucleoplasm Group enriched 6 parathyroid gland: 6.6;prostate: 1.4;testis: 5.8;thyroid gland: 3.5 epididymis: 0.6 -ADNP ADNP1, KIAA0784 ENSG00000101126 Activity-dependent neuroprotector homeobox 20 50888919-50931240 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006371 Supported Approved Nucleoplasm Expressed in all parathyroid gland: 80.3 -PFDN4 C-1, C1, PFD4 ENSG00000101132 Prefoldin subunit 4 20 54207847-54228052 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024055 Approved Mixed cerebral cortex: 11.3 -DOK5 C20orf180, dJ805C22.1 ENSG00000101134 Docking protein 5 20 54475597-54651171 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA054460, HPA065235 Uncertain Approved Focal adhesion sites Tissue enhanced 0 cerebral cortex: 22.1;fallopian tube: 19.8 skeletal muscle: 15.7 -CSTF1 ENSG00000101138 Cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 20 56392371-56406369 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019270, HPA047275, HPA065000 Supported Validated Nucleoplasm Expressed in all testis: 31.2 -BMP7 OP-1 ENSG00000101144 Bone morphogenetic protein 7 20 57168748-57266629 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057757 Approved Nucleus
Nucleoli
Vesicles Tissue enhanced 0 thyroid gland: 76.4 placenta: 36.6 -RAE1 Mnrp41 ENSG00000101146 Ribonucleic acid export 1 20 57351010-57379211 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048795 Supported Nucleus
Nucleoli fibrillar center Tissue enriched 6 testis: 182.6 bone marrow: 31.4 -TPD52L2 D54, hD54 ENSG00000101150 Tumor protein D52-like 2 20 63865228-63891545 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047489 Approved Approved Vesicles
Cytosol Expressed in all smooth muscle: 103.8 -DNAJC5 CLN4, DNAJC5A, FLJ00118, FLJ13070 ENSG00000101152 DnaJ (Hsp40) homolog, subfamily C, member 5 20 63895182-63936031 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012737, HPA013154 Approved Uncertain Golgi apparatus Expressed in all cerebral cortex: 73.8 -NELFCD HSPC130, NELF-C, NELF-D, TH1, TH1L ENSG00000101158 Negative elongation factor complex member C/D 20 58981208-58995133 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050641, HPA066262 Supported Nucleoplasm
Nuclear bodies
Vesicles
Cytosol Expressed in all parathyroid gland: 51.3 -CTSZ CTSX ENSG00000101160 Cathepsin Z 20 58995185-59007247 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025114, HPA049876, HPA053504 Supported Supported Vesicles Expressed in all lung: 477.4 -PRPF6 ANT-1, bB152O15.1, C20orf14, hPrp6, Prp6, RP60, SNRNP102, TOM, U5-102K ENSG00000101161 Pre-mRNA processing factor 6 20 63981135-64033100 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047106 Supported Validated Nuclear speckles Expressed in all fallopian tube: 79.5 -TUBB1 dJ543J19.4 ENSG00000101162 Tubulin, beta 1 class VI 20 59019254-59026654 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004286, HPA043640, HPA046280 Approved Supported Microtubules Group enriched 5 bone marrow: 4.8;lung: 1.9;placenta: 1.2;spleen: 5.3;testis: 1.5 gallbladder: 0.5 -PRELID3B C20orf45, dJ543J19.5, SLMO2 ENSG00000101166 PRELI domain containing 3B 20 59033145-59042909 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047721 Uncertain Approved Nucleus Expressed in all duodenum: 90.4 -HRH3 GPCR97 ENSG00000101180 Histamine receptor H3 20 62214970-62220267 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 17 cerebral cortex: 11.1 adrenal gland: 0.6 -MTG2 dJ1005F21.2, FLJ10741, GTPBP5, ObgH1 ENSG00000101181 Mitochondrial ribosome-associated GTPase 2 20 62183029-62203568 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047379 Approved Expressed in all adrenal gland: 15.9 -PSMA7 C6, HSPC, RC6-1, XAPC7 ENSG00000101182 Proteasome subunit alpha 7 20 62136735-62143440 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047266 Uncertain Expressed in all adipose tissue: 207.7 -SLCO4A1 OATP-E, OATP4A1, SLC21A12 ENSG00000101187 Solute carrier organic anion transporter family, member 4A1 20 62642445-62685785 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030669, HPA030670 Uncertain Approved Cell Junctions Mixed esophagus: 10.6 -NTSR1 NTR ENSG00000101188 Neurotensin receptor 1 (high affinity) 20 62708837-62762771 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050299 Supported Plasma membrane Not detected cerebral cortex: 0.5 -MRGBP C20orf20, Eaf7, FLJ10914, MRG15BP ENSG00000101189 MRG/MORF4L binding protein 20 62796453-62801738 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017012 Supported Supported Nucleus Tissue enriched 6 testis: 64.3 ovary: 10.6 -TCFL5 bHLHe82, CHA, E2BP-1, Figlb ENSG00000101190 Transcription factor-like 5 (basic helix-loop-helix) 20 62841115-62861763 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055223 Approved Supported Nucleoplasm Expressed in all testis: 143.8 -DIDO1 BYE1, C20orf158, DATF1, DIO-1, DIO1, dJ885L7.8, FLJ11265, KIAA0333 ENSG00000101191 Death inducer-obliterator 1 20 62877738-62937952 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004374, HPA049904 Supported Approved Nucleoplasm
Vesicles Expressed in all fallopian tube: 47.7 -GID8 bA305P22.1, C20orf11, FLJ20602, TWA1 ENSG00000101193 GID complex subunit 8 20 62938119-62948475 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049929, HPA055047 Approved Supported Nucleoplasm
Cell Junctions Expressed in all skin: 32.5 -SLC17A9 C20orf59, FLJ23412, VNUT ENSG00000101194 Solute carrier family 17 (vesicular nucleotide transporter), member 9 20 62952647-62969585 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA047470, HPA056499 Uncertain Approved Nucleoplasm Mixed stomach: 8.7 -BIRC7 KIAP, ML-IAP, mliap, RNF50 ENSG00000101197 Baculoviral IAP repeat containing 7 20 63235883-63240507 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA047850 Supported Nucleus
Microtubule organizing center
Cytosol Tissue enhanced 0 placenta: 9.1 skin: 2.7 -NKAIN4 bA261N11.2, C20orf58, FAM77A ENSG00000101198 Na+/K+ transporting ATPase interacting 4 20 63240784-63272694 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029876 Approved Tissue enriched 13 cerebral cortex: 71.9 kidney: 5.5 -ARFGAP1 ARF1GAP, bA261N11.3, FLJ10767 ENSG00000101199 ADP-ribosylation factor GTPase activating protein 1 20 63272785-63289793 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051019, HPA056273 Approved Supported Nuclear membrane
Golgi apparatus
Vesicles Expressed in all testis: 32.2 -AVP ADH, ARVP ENSG00000101200 Arginine vasopressin 20 3082556-3084724 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Not detected bone marrow: 0.5 -COL20A1 KIAA1510 ENSG00000101203 Collagen, type XX, alpha 1 20 63293186-63334851 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051962 Uncertain Tissue enriched 7 cerebral cortex: 16.2 testis: 2.3 -CHRNA4 BFNC, EBN, EBN1 ENSG00000101204 Cholinergic receptor, nicotinic, alpha 4 (neuronal) 20 63343223-63378401 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034064 Uncertain Tissue enhanced 0 cerebral cortex: 6.8;parathyroid gland: 16.9 liver: 3.7 -EEF1A2 EEF1AL, HS1, STN, STNL ENSG00000101210 Eukaryotic translation elongation factor 1 alpha 2 20 63488013-63499315 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034019, HPA051759, HPA053862, HPA056990 Approved Validated Nucleoli
Cytosol Group enriched 6 cerebral cortex: 410.5;heart muscle: 413.7;skeletal muscle: 1373.0 adrenal gland: 128.3 -PTK6 BRK ENSG00000101213 Protein tyrosine kinase 6 20 63528001-63537370 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032952, HPA036070, HPA036071 Approved Supported Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Tissue enhanced 0 esophagus: 61.2;skin: 60.6 duodenum: 30.0 -GMEB2 KIAA1269, P79PIF, PIF79 ENSG00000101216 Glucocorticoid modulatory element binding protein 2 20 63587602-63627041 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009706, HPA067455 Approved Validated Nucleoplasm Expressed in all testis: 12.8 -C20orf27 FLJ20550 ENSG00000101220 Chromosome 20 open reading frame 27 20 3753508-3768387 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047483 Approved Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 56.6 -SPEF1 C20orf28, DKFZP434I114, SPEF1A ENSG00000101222 Sperm flagellar 1 20 3777504-3781448 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA050786 Supported Tissue enhanced 0 fallopian tube: 15.8;testis: 6.5 cerebral cortex: 2.9 -CDC25B ENSG00000101224 Cell division cycle 25B 20 3786772-3806121 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038892, HPA038893 Approved Uncertain Nucleoplasm
Cytosol Mixed lymph node: 57.4 -ISM1 bA149I18.1, C20orf82 ENSG00000101230 Isthmin 1, angiogenesis inhibitor 20 13221771-13300651 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 thyroid gland: 74.2 placenta: 24.7 -RNF24 G1L ENSG00000101236 Ring finger protein 24 20 3927309-4015582 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011900 Approved Supported Golgi apparatus Mixed bone marrow: 34.3 -ARFRP1 ARL18, ARP, Arp1 ENSG00000101246 ADP-ribosylation factor related protein 1 20 63698642-63708025 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047028, HPA050634 Approved Supported Golgi apparatus Expressed in all spleen: 28.4 -NDUFAF5 C20orf7, dJ842G6.1 ENSG00000101247 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 20 13784950-13821582 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051184 Uncertain Mixed skeletal muscle: 6.9 -SEL1L2 C20orf50, DKFZp434C1826 ENSG00000101251 Sel-1 suppressor of lin-12-like 2 (C. elegans) 20 13849247-13996443 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059121 Approved Tissue enriched 63 testis: 12.5 seminal vesicle: 0.1 -TRIB3 C20orf97, dJ1103G7.3, TRB3 ENSG00000101255 Tribbles pseudokinase 3 20 362835-397559 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055442 Supported Nucleus
Nuclear membrane
Nucleoli Tissue enhanced 0 thyroid gland: 51.3 liver: 12.5 -RASSF2 CENP-34, KIAA0168 ENSG00000101265 Ras association (RalGDS/AF-6) domain family member 2 20 4780023-4823645 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051200 Uncertain Supported Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 148.9 lymph node: 69.7 -CSNK2A1 ENSG00000101266 Casein kinase 2, alpha 1 polypeptide 20 473591-543821 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020680, HPA059206, CAB069395 Approved Supported Nucleoplasm Expressed in all testis: 133.0 -SLC52A3 bA371L19.1, C20orf54, hRFT2, RFVT3 ENSG00000101276 Solute carrier family 52 (riboflavin transporter), member 3 20 760080-776015 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049391 Approved Tissue enhanced 0 testis: 62.2 small intestine: 18.5 -ANGPT4 ENSG00000101280 Angiopoietin 4 20 869899-916317 Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013260, CAB013305 Uncertain Tissue enhanced 0 cervix, uterine: 5.4 adipose tissue: 2.7 -RSPO4 C20orf182, dJ824F16.3 ENSG00000101282 R-spondin 4 20 958452-1002264 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048887 Uncertain Tissue enhanced 0 lung: 6.8 testis: 2.4 -CDS2 ENSG00000101290 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 20 5126786-5197887 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019698 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all cerebral cortex: 49.1 -PROKR2 dJ680N4.3, GPR73b, GPR73L1, GPRg2, KAL3, PKR2 ENSG00000101292 Prokineticin receptor 2 20 5302040-5314369 Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047281 Uncertain Tissue enhanced 0 cerebral cortex: 3.0 bone marrow: 0.8 -HM13 dJ324O17.1, H13, IMP1, IMPAS, PSENL3, PSL3, SPP, SPPL1 ENSG00000101294 Histocompatibility (minor) 13 20 31514428-31577923 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045089, HPA056062 Approved Supported Endoplasmic reticulum Expressed in all cervix: 153.3 -SNPH bA314N13.5 ENSG00000101298 Syntaphilin 20 1266316-1309328 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049393 Approved Uncertain Cytokinetic bridge
Mitochondria Tissue enhanced 0 cerebral cortex: 33.7 seminal vesicle: 15.4 -MYLK2 KMLC, MLCK2, skMLCK ENSG00000101306 Myosin light chain kinase 2 20 31819308-31834689 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059704, HPA059890 Approved Supported Endoplasmic reticulum Tissue enriched 49 skeletal muscle: 253.2 esophagus: 5.1 -SIRPB1 CD172b, SIRP-BETA-1 ENSG00000101307 Signal-regulatory protein beta 1 20 1563521-1620061 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047463 Uncertain Uncertain Vesicles Tissue enhanced 0 appendix: 39.7;bone marrow: 33.8 lung: 28.0 -SEC23B CDA-II, CDAII, CDAN2, HEMPAS ENSG00000101310 Sec23 homolog B, COPII coat complex component 20 18507493-18561415 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008216, HPA069974 Uncertain Supported Vesicles Expressed in all thyroid gland: 85.5 -FERMT1 C20orf42, FLJ20116, KIND1, UNC112A, URP1 ENSG00000101311 Fermitin family member 1 20 6074845-6123544 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039778, HPA041966 Approved Mixed rectum: 31.2 -HAO1 GOX, GOX1 ENSG00000101323 Hydroxyacid oxidase (glycolate oxidase) 1 20 7882981-7940474 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049552 Supported Tissue enriched 307 liver: 308.2 kidney: 1.0 -PDYN ADCA, PENKB, SCA23 ENSG00000101327 Prodynorphin 20 1978757-1994285 Disease related genes, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049841, HPA053342 Approved Tissue enriched 11 cerebral cortex: 63.5 testis: 5.5 -CCM2L C20orf160, dJ310O13.5 ENSG00000101331 Cerebral cavernous malformation 2-like 20 32010450-32032180 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008434, HPA071063 Uncertain Approved Nucleoplasm Tissue enriched 8 spleen: 124.7 placenta: 14.9 -PLCB4 ENSG00000101333 Phospholipase C, beta 4 20 9068763-9481242 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007951 Approved Nucleoplasm
Microtubules Tissue enhanced 0 thyroid gland: 58.3 epididymis: 29.9 -MYL9 LC20, MLC2, MRLC1, MYRL2 ENSG00000101335 Myosin, light chain 9, regulatory 20 36541484-36551447 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039262, HPA045244, HPA059197 Supported Approved Nucleus
Nucleoli fibrillar center Expressed in all seminal vesicle: 3106.0 -HCK JTK9 ENSG00000101336 HCK proto-oncogene, Src family tyrosine kinase 20 32052188-32101856 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005195, HPA063768 Approved Approved Nucleoplasm
Plasma membrane Tissue enhanced 0 appendix: 142.6;spleen: 108.6 lung: 67.5 -TM9SF4 dJ836N17.2, KIAA0255 ENSG00000101337 Transmembrane 9 superfamily protein member 4 20 32109506-32167258 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064099 Approved Approved Mitochondria Expressed in all parathyroid gland: 91.3 -TLDC2 C20orf118, dJ132F21.2 ENSG00000101342 TBC/LysM-associated domain containing 2 20 36876121-36894235 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA047468 Approved Mixed small intestine: 20.5 -CRNKL1 CLF, Clf1, CRN, SYF3 ENSG00000101343 Crooked neck pre-mRNA splicing factor 1 20 20034368-20056046 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 23.8 -POFUT1 FUT12, KIAA0180, O-Fuc-T, O-FUT ENSG00000101346 Protein O-fucosyltransferase 1 20 32207880-32238667 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054519, HPA059935 Approved Approved Centrosome Expressed in all parathyroid gland: 35.1 -SAMHD1 AGS5, HDDC1, Mg11, MOP-5, SBBI88 ENSG00000101347 SAM domain and HD domain 1 20 36890229-36951843 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047072 Supported Supported Nucleoplasm
Plasma membrane Expressed in all spleen: 135.3 -PAK7 KIAA1264, PAK5 ENSG00000101349 P21 protein (Cdc42/Rac)-activated kinase 7 20 9537389-9839041 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020444 Approved Approved Nucleoplasm Tissue enriched 5 cerebral cortex: 13.4 adrenal gland: 2.6 -KIF3B FLA8, KIAA0359, KLP-11 ENSG00000101350 Kinesin family member 3B 20 32277664-32335011 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007119 Approved Uncertain Nucleoplasm
Nucleoli
Golgi apparatus Expressed in all parathyroid gland: 79.3 -MROH8 C20orf131, C20orf132, dJ621N11.3, dJ621N11.4 ENSG00000101353 Maestro heat-like repeat family member 8 20 37101226-37179588 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060298 Uncertain Approved Nucleus Tissue enhanced 0 testis: 41.0 epididymis: 8.6 -NOP56 NOL5A, SCA36 ENSG00000101361 NOP56 ribonucleoprotein 20 2652145-2658393 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049918, CAB075757 Supported Validated Nucleoli fibrillar center Expressed in all fallopian tube: 59.6 -MANBAL dJ1141E15.2 ENSG00000101363 Mannosidase, beta A, lysosomal-like 20 37289638-37317260 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052348 Approved Nucleus
Mitochondria Expressed in all smooth muscle: 95.1 -IDH3B RP46 ENSG00000101365 Isocitrate dehydrogenase 3 (NAD+) beta 20 2658395-2664219 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049387, HPA054180 Supported Validated Mitochondria Expressed in all parathyroid gland: 98.7 -MAPRE1 EB1 ENSG00000101367 Microtubule-associated protein, RP/EB family, member 1 20 32819893-32850405 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003600, CAB009337, CAB019391 Supported Validated Microtubule organizing center
Cytosol Expressed in all smooth muscle: 126.8 -JAG1 AGS, AHD, AWS, CD339, HJ1, JAGL1 ENSG00000101384 Jagged 1 20 10637684-10674107 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010343, HPA021555 Supported Supported Golgi apparatus
Plasma membrane Expressed in all placenta: 96.3 -CDK5RAP1 C20orf34, C42, CGI-05, HSPC167 ENSG00000101391 CDK5 regulatory subunit associated protein 1 20 33358839-33401561 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066301 Approved Nuclear speckles
Mitochondria Expressed in all thyroid gland: 19.4 -SNTA1 LQT12, SNT1, TACIP1 ENSG00000101400 Syntrophin, alpha 1 20 33407955-33443892 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037059 Approved Expressed in all thyroid gland: 101.8 -OXT OT, OT-NPI, OXT-NPI ENSG00000101405 Oxytocin/neurophysin I prepropeptide 20 3071620-3072517 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 liver: 2.2 small intestine: 1.1 -TTI1 KIAA0406, smg-10 ENSG00000101407 TELO2 interacting protein 1 20 37983007-38033468 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034230, HPA068338 Uncertain Approved Nucleoplasm
Vesicles Expressed in all thyroid gland: 20.6 -E2F1 RBBP3, RBP3 ENSG00000101412 E2F transcription factor 1 20 33675683-33686404 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000329, HPA008003, CAB019308, HPA029735 Approved Validated Nucleoplasm
Centrosome Tissue enhanced 0 bone marrow: 22.9 testis: 12.7 -RPRD1B C20orf77, CREPT, dJ1057B20.2, DKFZp434P0735, FLJ44520, NET60 ENSG00000101413 Regulation of nuclear pre-mRNA domain containing 1B 20 38033546-38127780 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066290 Supported Nucleoplasm
Centrosome
Cytosol Expressed in all parathyroid gland: 29.0 -PXMP4 PMP24 ENSG00000101417 Peroxisomal membrane protein 4, 24kDa 20 33702754-33720319 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050077 Approved Approved Nucleoli fibrillar center
Peroxisomes Expressed in all parathyroid gland: 29.8 -CHMP4B C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B ENSG00000101421 Charged multivesicular body protein 4B 20 33811304-33854366 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041401, HPA051751 Supported Expressed in all cerebral cortex: 140.8 -BPI BPIFD1 ENSG00000101425 Bactericidal/permeability-increasing protein 20 38260149-38337505 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061284 Supported Tissue enriched 36 bone marrow: 963.1 testis: 27.0 -CST9L bA218C14.1, CTES7B ENSG00000101435 Cystatin 9-like 20 23564732-23568749 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 testis: 107.9 epididymis: 19.4 -SLC32A1 bA122O1.1, VGAT, VIAAT ENSG00000101438 Solute carrier family 32 (GABA vesicular transporter), member 1 20 38724462-38729372 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB037156, HPA058859, HPA059985 Supported Tissue enriched 34 cerebral cortex: 15.9 testis: 0.4 -CST3 ENSG00000101439 Cystatin C 20 23626706-23638473 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000118, HPA013143 Supported Supported Golgi apparatus
Vesicles Expressed in all cerebral cortex: 1269.6 -ASIP AGTIL, ASP ENSG00000101440 Agouti signaling protein 20 34194569-34269344 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048636 Uncertain Approved Vesicles Group enriched 5 epididymis: 18.6;ovary: 7.5;skin: 5.6 breast: 2.1 -CST4 ENSG00000101441 Cystatin S 20 23685640-23689040 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043706, HPA044763 Supported Tissue enriched 113 salivary gland: 9974.9 gallbladder: 88.0 -ACTR5 Arp5, FLJ12785, INO80M ENSG00000101442 ARP5 actin-related protein 5 homolog (yeast) 20 38748442-38772520 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042676 Approved Mixed testis: 16.6 -WFDC2 dJ461P17.6, EDDM4, HE4, WAP5 ENSG00000101443 WAP four-disulfide core domain 2 20 45469706-45481532 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042302 Supported Approved Cytosol Tissue enriched 6 cervix, uterine: 6507.3 seminal vesicle: 1038.0 -AHCY SAHH ENSG00000101444 Adenosylhomocysteinase 20 34280268-34311802 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041225, HPA044675 Approved Supported Cytosol Expressed in all thyroid gland: 158.6 -PPP1R16B ANKRD4, KIAA0823, TIMAP ENSG00000101445 Protein phosphatase 1, regulatory subunit 16B 20 38805705-38923024 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049571 Supported Nuclear speckles
Plasma membrane Tissue enhanced 0 cerebral cortex: 51.0 lymph node: 44.7 -SPINT3 HKIB9 ENSG00000101446 Serine peptidase inhibitor, Kunitz type, 3 20 45512461-45515624 Predicted secreted proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA057848 Uncertain Group enriched 31 epididymis: 5.7;seminal vesicle: 15.2 prostate: 0.3 -FAM83D C20orf129, dJ616B8.3 ENSG00000101447 Family with sequence similarity 83, member D 20 38926312-38953106 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049333 Approved Tissue enhanced 0 esophagus: 76.4;smooth muscle: 130.1 gallbladder: 21.3 -EPPIN CT71, dJ461P17.2, EPPIN1, EPPIN2, EPPIN3, SPINLW1, WAP7, WFDC7 ENSG00000101448 Epididymal peptidase inhibitor 20 45540626-45547752 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 102 epididymis: 409.0;testis: 129.0 fallopian tube: 2.6 -DHX35 C20orf15, DDX35, FLJ22759, KAIA0875 ENSG00000101452 DEAH (Asp-Glu-Ala-His) box polypeptide 35 20 38962299-39039723 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054451, HPA062700 Uncertain Approved Nucleus
Nuclear bodies
Centrosome Mixed endometrium: 14.8 -DNTTIP1 C20orf167, dJ447F3.4, Tdif1 ENSG00000101457 Deoxynucleotidyltransferase, terminal, interacting protein 1 20 45791937-45811427 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042479, HPA045496 Validated Nucleus Expressed in all testis: 44.6 -MAP1LC3A ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3 ENSG00000101460 Microtubule-associated protein 1 light chain 3 alpha 20 34546854-34560345 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007649, CAB037174, HPA043000, HPA052474, HPA052484 Supported Supported Microtubule organizing center Expressed in all cerebral cortex: 119.4 -SYNDIG1 C20orf39, FLJ14220, IFITMD5, SynDIG1, TMEM90B ENSG00000101463 Synapse differentiation inducing 1 20 24469199-24666616 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059267 Uncertain Supported Vesicles Tissue enhanced 0 cerebral cortex: 26.9 heart muscle: 14.6 -PIGU bA346K17.2, CDC91L1, GAB1 ENSG00000101464 Phosphatidylinositol glycan anchor biosynthesis, class U 20 34560542-34698790 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041706, HPA046766 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 47.2 -TNNC2 ENSG00000101470 Troponin C type 2 (fast) 20 45823214-45833745 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043174, HPA058481 Supported Approved Nucleoplasm
Vesicles Tissue enriched 78 skeletal muscle: 9900.8 esophagus: 127.0 -ACOT8 hACTE-III, hTE, NAP1, PTE-2, PTE1 ENSG00000101473 Acyl-CoA thioesterase 8 20 45841721-45857406 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010261 Approved Supported Vesicles
Mitochondria Expressed in all cerebral cortex: 30.1 -APMAP BSCv, C20orf3 ENSG00000101474 Adipocyte plasma membrane associated protein 20 24962925-24992979 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012863, HPA064700 Uncertain Approved Plasma membrane Expressed in all thyroid gland: 322.5 -CELF4 BRUNOL4 ENSG00000101489 CUGBP, Elav-like family member 4 18 37243047-37566037 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037986 Approved Tissue enriched 9 cerebral cortex: 127.3 adrenal gland: 14.7 -ZNF516 HsT287, KIAA0222 ENSG00000101493 Zinc finger protein 516 18 76358190-76495190 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015792 Uncertain Approved Nucleoplasm
Cytosol Expressed in all endometrium: 54.1 -CDH20 Cdh7, CDH7L3 ENSG00000101542 Cadherin 20, type 2 18 61333582-61555773 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015490 Uncertain Tissue enriched 5 cerebral cortex: 26.9 adipose tissue: 4.9 -ADNP2 KIAA0863, ZNF508 ENSG00000101544 ADNP homeobox 2 18 80109031-80147523 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007126 Uncertain Approved Mitochondria
Cytosol Mixed testis: 39.6 -RBFA C18orf22, FLJ21172, HsT169 ENSG00000101546 Ribosome binding factor A (putative) 18 80034358-80046397 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040485, HPA041479 Approved Supported Mitochondria Expressed in all adipose tissue: 20.3 -USP14 TGT ENSG00000101557 Ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 18 158383-214629 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001308 Approved Supported Cytosol Expressed in all prostate: 49.2 -VAPA hVAP-33, VAP-A ENSG00000101558 VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 18 9914002-9960021 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009174 Approved Validated Endoplasmic reticulum Expressed in all adrenal gland: 61.6 -METTL4 FLJ23017, HsT661 ENSG00000101574 Methyltransferase like 4 18 2537525-2571509 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040061 Approved Approved Mitochondria Expressed in all thyroid gland: 17.2 -LPIN2 KIAA0249 ENSG00000101577 Lipin 2 18 2916994-3013315 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015223, HPA017857, HPA030550 Supported Supported Plasma membrane
Actin filaments
Cytosol Mixed liver: 86.9 -SMCHD1 KIAA0650 ENSG00000101596 Structural maintenance of chromosomes flexible hinge domain containing 1 18 2655738-2805017 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039441 Approved Approved Nucleoplasm
Nuclear bodies Expressed in all spleen: 41.1 -MYOM1 ENSG00000101605 Myomesin 1 18 3066807-3220108 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014305, HPA049193 Supported Group enriched 12 heart muscle: 260.5;skeletal muscle: 299.2 gallbladder: 22.9 -MYL12A MLCB, MRCL3, MRLC3, MYL2B ENSG00000101608 Myosin, light chain 12A, regulatory, non-sarcomeric 18 3247481-3256236 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004503, HPA039262, HPA045244, HPA059197 Supported Approved Nucleus
Nucleoli fibrillar center Expressed in all heart muscle: 2307.5 -CEP76 C18orf9, FLJ12542, HsT1705 ENSG00000101624 Centrosomal protein 76kDa 18 12661833-12702777 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039395 Approved Mixed testis: 14.9 -ST8SIA5 SIAT8E ENSG00000101638 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 18 46667821-46759257 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043813, HPA046771 Approved Approved Plasma membrane
Midbody Tissue enhanced 0 adrenal gland: 5.5;cerebral cortex: 11.5 parathyroid gland: 3.4 -CEP192 FLJ10352, KIAA1569, PPP1R62 ENSG00000101639 Centrosomal protein 192kDa 18 12991362-13125052 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039392, HPA040503 Uncertain Approved Centrosome
Cytosol Mixed testis: 17.2 -RNMT RG7MT1 ENSG00000101654 RNA (guanine-7-) methyltransferase 18 13726660-13764558 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039409 Approved Validated Nucleoplasm
Nucleoli fibrillar center Expressed in all testis: 30.8 -SMAD7 MADH7, MADH8 ENSG00000101665 SMAD family member 7 18 48919853-48950711 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB026212, HPA028897 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 41.1 -LIPG EDL ENSG00000101670 Lipase, endothelial 18 49560699-49599182 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016966 Uncertain Group enriched 11 placenta: 212.7;thyroid gland: 402.1 seminal vesicle: 28.8 -LAMA1 LAMA ENSG00000101680 Laminin, alpha 1 18 6941744-7117814 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010179, HPA032110 Approved Tissue enhanced 0 testis: 11.0;thyroid gland: 4.2 kidney: 2.1 -RNF125 FLJ20456 ENSG00000101695 Ring finger protein 125, E3 ubiquitin protein ligase 18 32018372-32073213 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041514 Uncertain Uncertain Nucleoli
Golgi apparatus
Cytosol Mixed small intestine: 11.8 -ANKRD12 FLJ20053, GAC-1, KIAA0874 ENSG00000101745 Ankyrin repeat domain 12 18 9136228-9285985 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040705 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 54.2 -NOL4 CT125, HRIHFB2255, NOLP ENSG00000101746 Nucleolar protein 4 18 33851100-34224952 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046740 Supported Nucleus Group enriched 7 cerebral cortex: 16.0;testis: 22.7 thyroid gland: 2.9 -POLI RAD30B, RAD3OB ENSG00000101751 Polymerase (DNA directed) iota 18 54269404-54321266 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012000, HPA064696 Supported Supported Nuclear speckles
Cytoplasmic bodies Expressed in all testis: 69.3 -MIB1 DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6 ENSG00000101752 Mindbomb E3 ubiquitin protein ligase 1 18 21704957-21870957 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019100, CAB037044 Approved Approved Nuclear membrane
Vesicles
Plasma membrane Expressed in all thyroid gland: 24.1 -RBBP8 COM1, CtIP, RIM, SCKL2 ENSG00000101773 Retinoblastoma binding protein 8 18 22798261-23026488 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039890, HPA052946 Approved Supported Nucleoplasm Mixed testis: 52.6 -RIOK3 SUDD ENSG00000101782 RIO kinase 3 18 23452823-23486603 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001620, HPA024184 Approved Approved Golgi apparatus
Plasma membrane
Microtubule organizing center
Cytosol Expressed in all bone marrow: 75.0 -CSTF2 ENSG00000101811 Cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa X 100820359-100840932 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000427, CAB004680 Supported Validated Nucleoplasm
Nuclear bodies Mixed testis: 25.6 -H2BFM ENSG00000101812 H2B histone family, member M X 104039949-104042454 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed testis: 2.4 -MXRA5 DKFZp564I1922 ENSG00000101825 Matrix-remodelling associated 5 X 3308565-3346641 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000508 Uncertain Uncertain Mitochondria Tissue enhanced 0 cervix, uterine: 56.8 skin: 35.3 -VSIG1 MGC44287 ENSG00000101842 V-set and immunoglobulin domain containing 1 X 108044970-108079184 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001445, HPA036310, HPA036311 Supported Approved Vesicles
Cytosol Group enriched 10 stomach: 187.2;testis: 90.9 gallbladder: 14.3 -PSMD10 p28 ENSG00000101843 Proteasome 26S subunit, non-ATPase 10 X 108084207-108091618 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002920, CAB010434 Approved Supported Intermediate filaments
Cytosol Expressed in all cerebral cortex: 70.2 -ATG4A APG4A, AUTL2 ENSG00000101844 Autophagy related 4A, cysteine peptidase X 108091668-108154671 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036374, HPA064759 Uncertain Approved Actin filaments
Microtubules Expressed in all thyroid gland: 17.7 -STS ARSC, ARSC1 ENSG00000101846 Steroid sulfatase (microsomal), isozyme S X 7219456-7354810 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002904 Approved Tissue enhanced 0 placenta: 36.3 adipose tissue: 18.9 -TBL1X EBI, TBL1 ENSG00000101849 Transducin (beta)-like 1X-linked X 9463295-9719743 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB005363, HPA067703 Approved Approved Nucleus
Nucleoli Expressed in all endometrium: 63.5 -GPR143 OA1 ENSG00000101850 G protein-coupled receptor 143 X 9725346-9786297 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003648 Approved Mixed skin: 10.3 -PGRMC1 HPR6.6 ENSG00000101856 Progesterone receptor membrane component 1 X 119236245-119244466 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002877 Supported Approved Nucleoli
Endoplasmic reticulum Expressed in all liver: 339.5 -POLA1 NSX, p180, POLA ENSG00000101868 Polymerase (DNA directed), alpha 1, catalytic subunit X 24693919-24996986 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002947, CAB012274 Supported Supported Nucleoplasm
Cytosol Mixed lymph node: 8.8 -MID1 FXY, OS, RNF59, TRIM18 ENSG00000101871 Midline 1 X 10445310-10833654 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003715 Approved Mixed seminal vesicle: 20.4 -NKAP FLJ22626 ENSG00000101882 NFKB activating protein X 119920672-119943772 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000916 Approved Supported Nucleoplasm
Cytosol Mixed ovary: 6.5 -RHOXF1 OTEX, PEPP1 ENSG00000101883 Rhox homeobox family, member 1 X 120109053-120115937 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056506 Approved Tissue enriched 9 testis: 15.5 adipose tissue: 1.6 -NXT2 P15-2 ENSG00000101888 Nuclear transport factor 2-like export factor 2 X 109535781-109544690 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024199, HPA072010 Approved Supported Nucleoplasm
Cytosol Mixed testis: 51.8 -GUCY2F CYGF, GC-F, GUC2DL, RetGC-2, ROS-GC2 ENSG00000101890 Guanylate cyclase 2F, retinal X 109372906-109482072 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected testis: 0.4 -ATP1B4 ENSG00000101892 ATPase, Na+/K+ transporting, beta 4 polypeptide X 120362085-120383249 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 11 skeletal muscle: 20.5 prostate: 1.9 -ALG13 CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W ENSG00000101901 ALG13, UDP-N-acetylglucosaminyltransferase subunit X 111665811-111760649 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002853 Approved Expressed in all thyroid gland: 30.3 -PRPS2 ENSG00000101911 Phosphoribosyl pyrophosphate synthetase 2 X 12791355-12824222 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067599, CAB070417 Approved Approved Vesicles Tissue enhanced 0 testis: 241.5 seminal vesicle: 115.9 -TLR8 CD288 ENSG00000101916 Toll-like receptor 8 X 12906620-12923169 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001608 Supported Tissue enhanced 0 appendix: 23.8;spleen: 18.6 lung: 15.6 -MOSPD1 dJ473B4 ENSG00000101928 Motile sperm domain containing 1 X 134887626-134915267 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031158 Approved Approved Nucleoplasm
Vesicles Expressed in all fallopian tube: 41.8 -AMMECR1 ENSG00000101935 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 X 110194186-110440233 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000590, HPA051762 Uncertain Mixed placenta: 9.7 -CHRDL1 CHL, MGC1, NRLN1 ENSG00000101938 Chordin-like 1 X 110673856-110795819 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000226, HPA000250 Approved Tissue enhanced 0 seminal vesicle: 383.4 parathyroid gland: 310.6 -WDR13 ENSG00000101940 WD repeat domain 13 X 48590042-48608867 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000913 Supported Supported Nucleoplasm
Plasma membrane
Microtubule organizing center Expressed in all fallopian tube: 90.6 -SUV39H1 KMT1A, SUV39H ENSG00000101945 Suppressor of variegation 3-9 homolog 1 (Drosophila) X 48695554-48709012 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed epididymis: 14.3 -PAGE4 CT16.7, GAGEC1, PAGE-4 ENSG00000101951 P antigen family, member 4 (prostate associated) X 49829260-49833973 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023880 Supported Approved Golgi apparatus
Vesicles Group enriched 6 epididymis: 1431.1;placenta: 2026.4 prostate: 279.7 -SRPX ETX1 ENSG00000101955 Sushi-repeat containing protein, X-linked X 38149336-38220924 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adipose tissue: 161.2 placenta: 121.2 -GLRA2 GLR ENSG00000101958 Glycine receptor, alpha 2 X 14529298-14731812 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB070422 Approved Group enriched 10 cerebral cortex: 6.2;colon: 1.4;rectum: 4.3 testis: 0.3 -XIAP API3, BIRC4, hILP ENSG00000101966 X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase X 123859724-123913979 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009203, HPA042428 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 35.0 -STAG2 SA-2, SA2, SCC3B ENSG00000101972 Stromal antigen 2 X 123960212-124422664 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002857 Supported Expressed in all parathyroid gland: 110.6 -ATP11C ATPIG, ATPIQ ENSG00000101974 ATPase, class VI, type 11C X 139726346-139945276 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030830 Approved Mixed liver: 25.6 -MCF2 ARHGEF21, DBL ENSG00000101977 MCF.2 cell line derived transforming sequence X 139581770-139708227 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 10 adrenal gland: 38.5;cerebral cortex: 8.7;epididymis: 14.7;ovary: 12.8;seminal vesicle: 23.7;testis: 34.4 prostate: 2.1 -F9 FIX ENSG00000101981 Coagulation factor IX X 139530758-139563458 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 2286 liver: 364.7 kidney: 0.1 -ABCD1 adrenoleukodystrophy, ALD, ALDP, AMN ENSG00000101986 ATP-binding cassette, sub-family D (ALD), member 1 X 153724868-153744762 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all small intestine: 19.7 -CCDC22 CXorf37, JM1 ENSG00000101997 Coiled-coil domain containing 22 X 49235467-49250526 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000888 Uncertain Approved Nucleoplasm
Cytosol Expressed in all spleen: 18.8 -CACNA1F AIED, Cav1.4, CORDX3, CSNB2, CSNB2A, CSNBX2, JM8, JMC8, OA2 ENSG00000102001 Calcium channel, voltage-dependent, L type, alpha 1F subunit X 49205063-49233371 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed lymph node: 1.6 -SYP MRX96 ENSG00000102003 Synaptophysin X 49187804-49200259 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000076, HPA002858, CAB055505 Supported Tissue enriched 11 cerebral cortex: 573.3 adrenal gland: 51.4 -PLP2 A4, A4-LSB, MGC126187 ENSG00000102007 Proteolipid protein 2 (colonic epithelium-enriched) X 49171926-49175239 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042415 Approved Expressed in all skin: 480.7 -BMX ETK, PSCTK3 ENSG00000102010 BMX non-receptor tyrosine kinase X 15464246-15556529 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001048, CAB032495 Supported Supported Nucleoplasm
Plasma membrane Tissue enriched 18 epididymis: 122.9 placenta: 6.9 -LUZP4 CT-8, CT28, HOM-TES-85 ENSG00000102021 Leucine zipper protein 4 X 115289727-115307556 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046436, HPA051999 Supported Tissue enriched 156 testis: 15.6 epididymis: 0.0 -PLS3 T-plastin ENSG00000102024 Plastin 3 X 115561174-115650861 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020433, HPA076083 Approved Approved Plasma membrane
Cytosol Mixed thyroid gland: 291.7 -NAA10 ARD1, ARD1A, DXS707, TE2 ENSG00000102030 N(alpha)-acetyltransferase 10, NatA catalytic subunit X 153929242-153935223 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006269, HPA030711 Supported Validated Nucleoli
Cytosol Expressed in all smooth muscle: 25.3 -RENBP RBP, RNBP ENSG00000102032 Renin binding protein X 153935263-153944691 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000428, HPA000522 Supported Tissue enhanced 0 spleen: 59.6 kidney: 37.8 -ELF4 ELFR, MEF ENSG00000102034 E74-like factor 4 (ets domain transcription factor) X 130064874-130110716 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058595, HPA060277 Approved Supported Nucleoplasm
Nuclear bodies Mixed placenta: 34.7 -SMARCA1 hSNF2L, ISWI, NURF140, SNF2L, SNF2L1, SNF2LB, SWI ENSG00000102038 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 X 129446501-129523500 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003335, HPA064712 Uncertain Supported Nucleoplasm
Vesicles Mixed testis: 112.7 -MTMR8 FLJ20126 ENSG00000102043 Myotubularin related protein 8 X 64268081-64395431 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed fallopian tube: 3.7 -ASB9 DKFZP564L0862, FLJ20636, MGC4954 ENSG00000102048 Ankyrin repeat and SOCS box containing 9 X 15235288-15270467 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003014, HPA003060, CAB004997 Supported Supported Nucleus
Cytosol Tissue enhanced 0 testis: 48.1 kidney: 16.8 -ZC3H12B CXorf32, MCPIP2 ENSG00000102053 Zinc finger CCCH-type containing 12B X 65366638-65507887 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000836 Uncertain Approved Endoplasmic reticulum
Golgi apparatus
Vesicles Mixed cerebral cortex: 4.6 -RBBP7 RbAp46 ENSG00000102054 Retinoblastoma binding protein 7 X 16839283-16870414 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037084, HPA060710, HPA060724 Supported Supported Nucleoplasm Expressed in all adrenal gland: 377.8 -KCND1 Kv4.1 ENSG00000102057 Potassium channel, voltage gated Shal related subfamily D, member 1 X 48961378-48971569 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA000524, HPA001066 Approved Approved Nucleus Mixed gallbladder: 4.0 -OPN1LW CBBM, CBP, COD5, RCP ENSG00000102076 Opsin 1 (cone pigments), long-wave-sensitive X 154144224-154159032 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.1 -SLC25A14 BMCP1, UCP5 ENSG00000102078 Solute carrier family 25 (mitochondrial carrier, brain), member 14 X 130339888-130373361 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA060316 Approved Mitochondria Mixed cerebral cortex: 20.5 -FMR1 FMRP, FRAXA, MGC87458, POF, POF1 ENSG00000102081 Fragile X mental retardation 1 X 147911951-147951125 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012444, HPA050118, HPA056084 Approved Validated Cytosol Expressed in all parathyroid gland: 54.5 -PIM2 ENSG00000102096 Pim-2 proto-oncogene, serine/threonine kinase X 48913182-48919024 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000285 Approved Approved Cytosol Mixed lymph node: 130.6 -SCML2 ENSG00000102098 Sex comb on midleg-like 2 (Drosophila) X 18239314-18354727 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001662, HPA064713 Approved Approved Nucleoli
Cytosol Tissue enhanced 0 testis: 19.1 ovary: 6.2 -SLC35A2 UGALT, UGAT, UGT, UGT1, UGT2, UGTL ENSG00000102100 Solute carrier family 35 (UDP-galactose transporter), member A2 X 48903180-48911958 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036087 Approved Supported Golgi apparatus Expressed in all fallopian tube: 44.1 -PQBP1 MRX2, MRX55, MRXS8, RENS1, SHS ENSG00000102103 Polyglutamine binding protein 1 X 48897912-48903143 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001880 Supported Validated Nuclear speckles Expressed in all ovary: 49.9 -RS1 RS, XLRS1 ENSG00000102104 Retinoschisin 1 X 18639910-18672109 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059546 Supported Group enriched 8 cerebral cortex: 1.1;lung: 1.7 thyroid gland: 0.1 -PCSK1N SAAS, SCG8, SgVIII ENSG00000102109 Proprotein convertase subtilisin/kexin type 1 inhibitor X 48831094-48835633 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003925, HPA064734 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 93.9;kidney: 65.8 adrenal gland: 28.6 -EMD LEMD5, STA ENSG00000102119 Emerin X 154379197-154381523 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000609, CAB001545, CAB002029, CAB062552 Supported Validated Nuclear membrane
Endoplasmic reticulum Expressed in all fallopian tube: 32.3 -TAZ BTHS, CMD3A, EFE, EFE2, G4.5, XAP-2 ENSG00000102125 Tafazzin X 154411518-154421726 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039557 Approved Approved Plasma membrane Expressed in all spleen: 21.2 -RAB40AL RAR2, RLGP ENSG00000102128 RAB40A, member RAS oncogene family-like X 102937250-102938962 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 epididymis: 3.7;esophagus: 2.0 prostate: 1.8 -PGK1 ENSG00000102144 Phosphoglycerate kinase 1 X 78065188-78129296 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010065, HPA045385 Approved Expressed in all parathyroid gland: 116.6 -GATA1 ERYF1, GATA-1, GF1, NF-E1, NFE1 ENSG00000102145 GATA binding protein 1 (globin transcription factor 1) X 48786554-48794311 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000232, HPA000233, CAB009195 Supported Tissue enriched 18 bone marrow: 33.3 testis: 1.8 -MAGT1 DKFZp564K142, IAP, MRX95, OST3B ENSG00000102158 Magnesium transporter 1 X 77826364-77895593 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049851 Approved Expressed in all thyroid gland: 136.9 -SMS MRSR, SPMSY, SpS, SRS ENSG00000102172 Spermine synthase X 21940573-21994835 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029849, HPA029852 Approved Approved Nuclear bodies
Cytosol Expressed in all prostate: 214.9 -PHEX HPDR, HPDR1, HYP, HYP1, PEX, XLH ENSG00000102174 Phosphate regulating endopeptidase homolog, X-linked X 22032441-22251310 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed endometrium: 3.5 -UBL4A DXS254E, GDX, GET5, MDY2, TMA24, UBL4 ENSG00000102178 Ubiquitin-like 4A X 154483717-154486670 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003617 Approved Expressed in all skeletal muscle: 31.8 -CD99L2 CD99B, MIC2L1 ENSG00000102181 CD99 molecule-like 2 X 150766337-150898816 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038782, HPA038783 Supported Uncertain Golgi apparatus
Plasma membrane
Intermediate filaments Expressed in all cerebral cortex: 143.9 -EEA1 ZFYVE2 ENSG00000102189 Early endosome antigen 1 12 92770637-92929331 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005861, CAB018782, HPA038158, HPA038159 Supported Supported Vesicles Expressed in all parathyroid gland: 16.5 -GPR50 H9, Mel1c ENSG00000102195 G protein-coupled receptor 50 X 151176653-151181465 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049862, HPA054678 Supported Supported Nucleoplasm
Plasma membrane Not detected placenta: 0.6 -RP2 NM23-H10, NME10, TBCCD2 ENSG00000102218 Retinitis pigmentosa 2 (X-linked recessive) X 46836940-46882358 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000234, HPA000909 Uncertain Approved Nucleoplasm
Nuclear bodies
Plasma membrane Mixed placenta: 34.8 -JADE3 JADE-3, KIAA0215, PHF16 ENSG00000102221 Jade family PHD finger 3 X 46912276-47061242 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006007, HPA064697 Uncertain Approved Nucleus
Nucleoli Mixed testis: 22.5 -CDK16 FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1 ENSG00000102225 Cyclin-dependent kinase 16 X 47217860-47229997 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000974, HPA001366, CAB016535 Approved Uncertain Plasma membrane
Microtubules
Cytosol Expressed in all cerebral cortex: 97.2 -USP11 UHX1 ENSG00000102226 Ubiquitin specific peptidase 11 X 47232690-47248328 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003103, HPA037536 Supported Approved Supported Nucleoplasm Expressed in all cerebral cortex: 213.4 -PCYT1B CCT-beta, CTB ENSG00000102230 Phosphate cytidylyltransferase 1, choline, beta X 24558087-24672677 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006367 Uncertain Tissue enhanced 0 cerebral cortex: 22.0;testis: 17.4 smooth muscle: 4.7 -BRS3 BB3 ENSG00000102239 Bombesin-like receptor 3 X 136487887-136493780 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 33 epididymis: 30.1 ovary: 0.9 -HTATSF1 TAT-SF1 ENSG00000102241 HIV-1 Tat specific factor 1 X 136497079-136512346 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000504 Supported Validated Nucleoplasm Expressed in all adrenal gland: 126.3 -VGLL1 TDU, TONDU ENSG00000102243 Vestigial-like family member 1 X 136532152-136556807 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042403, HPA064616 Supported Supported Nucleus Tissue enriched 13 placenta: 255.8 urinary bladder: 19.0 -CD40LG CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP ENSG00000102245 CD40 ligand X 136648193-136660390 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045827 Supported Tissue enhanced 0 lymph node: 19.0;tonsil: 14.7 appendix: 10.9 -TIMP1 CLGI, EPO, TIMP ENSG00000102265 TIMP metallopeptidase inhibitor 1 X 47582313-47586789 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022360, HPA053417 Approved Approved Golgi apparatus Expressed in all appendix: 2083.7 -KLHL4 DKELCHL, KHL4, KIAA1687 ENSG00000102271 Kelch-like family member 4 X 87517749-87670050 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029192 Approved Supported Microtubules
Microtubule organizing center Tissue enhanced 0 adrenal gland: 37.4 testis: 15.5 -GABRE ENSG00000102287 Gamma-aminobutyric acid (GABA) A receptor, epsilon X 151953124-151974680 FDA approved drug targets, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045918 Uncertain Tissue enhanced 0 adipose tissue: 10.1 heart muscle: 5.5 -PCDH11X PCDH-X, PCDH11, PCDHX, PPP1R119 ENSG00000102290 Protocadherin 11 X-linked X 91779261-92623230 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000432 Approved Tissue enhanced 0 cerebral cortex: 5.3;ovary: 9.9;parathyroid gland: 4.8 cervix: 1.7 -FGD1 FGDY, ZFYVE3 ENSG00000102302 FYVE, RhoGEF and PH domain containing 1 X 54445454-54496166 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000911 Uncertain Approved Plasma membrane
Cytosol Mixed endometrium: 10.1 -PIN4 EPVH, PAR14, PAR17 ENSG00000102309 Peptidylprolyl cis/trans isomerase, NIMA-interacting 4 X 72181353-72302926 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054483, HPA064504 Approved Supported Nucleus
Nucleoli Expressed in all epididymis: 24.0 -PORCN DHOF, MG61, por, PORC, PPN ENSG00000102312 Porcupine homolog (Drosophila) X 48508962-48520814 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049215, HPA058413 Approved Approved Vesicles Mixed adrenal gland: 34.6 -ITIH6 ITIH5L, UNQ6369 ENSG00000102313 Inter-alpha-trypsin inhibitor heavy chain family, member 6 X 54748899-54798240 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000506 Uncertain Not detected prostate: 0.6 -MAGED2 11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386 ENSG00000102316 Melanoma antigen family D2 X 54807599-54816012 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031572, HPA031573 Supported Validated Nucleus
Nucleoli
Cytosol Expressed in all prostate: 313.4 -RBM3 IS1-RNPL ENSG00000102317 RNA binding motif (RNP1, RRM) protein 3 X 48574449-48579066 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003624, CAB062559 Approved Validated Nucleoplasm Expressed in all breast: 235.9 -KLF8 BKLF3, DXS741, ZNF741 ENSG00000102349 Kruppel-like factor 8 X 56232421-56287889 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA071740 Supported Nucleoplasm Tissue enhanced 0 skin: 33.9 esophagus: 17.0 -SRPX2 SRPUL ENSG00000102359 Sushi-repeat containing protein, X-linked 2 X 100644218-100671299 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038786 Uncertain Approved Microtubules Mixed adipose tissue: 27.1 -SYTL4 ENSG00000102362 Synaptotagmin-like 4 X 100674491-100732123 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001475, HPA001589 Approved Approved Nucleoplasm
Microtubule organizing center
Cytosol Tissue enhanced 0 endometrium: 71.4;ovary: 83.9 smooth muscle: 48.7 -ZDHHC15 FLJ31812, MRX91 ENSG00000102383 Zinc finger, DHHC-type containing 15 X 75368427-75523502 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003618 Uncertain Approved Nuclear speckles
Cytosol Mixed cerebral cortex: 4.8 -CENPI CENP-I, FSHPRH1, LRPR1, Mis6 ENSG00000102384 Centromere protein I X 101098218-101163681 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061297 Supported Nuclear bodies
Cytosol Mixed lymph node: 6.7 -DRP2 ENSG00000102385 Dystrophin related protein 2 X 101219769-101264497 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA002949 Supported Tissue enriched 6 cerebral cortex: 12.3 prostate: 2.1 -TAF7L CT40, TAF2Q ENSG00000102387 TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa X 101268253-101293057 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA001879 Approved Approved Nucleoplasm Tissue enriched 14 testis: 62.4 parathyroid gland: 4.5 -PBDC1 CXorf26, MGC874 ENSG00000102390 Polysaccharide biosynthesis domain containing 1 X 76172936-76178204 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003155 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all prostate: 41.0 -GLA GALA ENSG00000102393 Galactosidase, alpha X 101397803-101407925 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000237, HPA000966 Supported Expressed in all seminal vesicle: 58.5 -ARMCX3 ALEX3, GASP6 ENSG00000102401 Armadillo repeat containing, X-linked 3 X 101622797-101627843 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000325, HPA000967, HPA001530 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 165.0 -BEX4 BEXL1, FLJ10097 ENSG00000102409 Brain expressed, X-linked 4 X 103215092-103217246 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045105, HPA051935 Uncertain Approved Nucleus
Cytosol Expressed in all epididymis: 318.7 -KIAA0226L C13orf18, FLJ21562 ENSG00000102445 KIAA0226-like 13 46342000-46438190 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026614 Approved Supported Cytosol Mixed lymph node: 35.4 -NALCN bA430M15.1, CanIon, VGCNL1 ENSG00000102452 Sodium leak channel, non selective 13 101053776-101416492 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031889, HPA031890, HPA031958 Approved Tissue enhanced 0 cerebral cortex: 28.2 adrenal gland: 6.0 -FGF14 FHF4, SCA27 ENSG00000102466 Fibroblast growth factor 14 13 101710804-102402457 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049828 Approved Nucleoli fibrillar center Tissue enhanced 0 cerebral cortex: 14.8;cervix, uterine: 22.8;fallopian tube: 17.1 testis: 4.2 -HTR2A 5-HT2A, HTR2 ENSG00000102468 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13 46831550-46897076 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014011 Supported Tissue enriched 8 cerebral cortex: 32.3 smooth muscle: 3.8 -NDFIP2 KIAA1165, N4wbp5a ENSG00000102471 Nedd4 family interacting protein 2 13 79481124-79556075 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009160 Uncertain Validated Vesicles Expressed in all cerebral cortex: 96.3 -TNFSF13B BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20 ENSG00000102524 Tumor necrosis factor (ligand) superfamily, member 13b 13 108251240-108308484 Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009188 Approved Mixed appendix: 36.2 -FNDC3A bA203I16.5, FNDC3, KIAA0970 ENSG00000102531 Fibronectin type III domain containing 3A 13 48975912-49209779 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008927, HPA012825 Approved Approved Endoplasmic reticulum Expressed in all thyroid gland: 85.5 -MLNR GPR38 ENSG00000102539 Motilin receptor 13 49220338-49222377 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 thyroid gland: 2.8 bone marrow: 0.8 -CDADC1 NYD-SP15 ENSG00000102543 Cytidine and dCMP deaminase domain containing 1 13 49247925-49293485 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047615, HPA058314 Uncertain Approved Nucleoplasm Mixed thyroid gland: 15.7 -CAB39L bA103J18.3, FLJ12577, MO2L ENSG00000102547 Calcium binding protein 39-like 13 49308650-49444126 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003686, HPA045954 Uncertain Approved Vesicles Expressed in all prostate: 64.2 -KLF5 BTEB2, CKLF, IKLF ENSG00000102554 Kruppel-like factor 5 (intestinal) 13 73054976-73077542 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040398 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Tissue enhanced 0 skin: 280.2 esophagus: 217.1 -STK24 MST-3, MST3, MST3B, STE20, STK3 ENSG00000102572 Serine/threonine kinase 24 13 98445185-98577940 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026435, HPA026502 Supported Supported Nucleoli
Cytosol Expressed in all esophagus: 170.1 -ACP5 HPAP, TRAP ENSG00000102575 Acid phosphatase 5, tartrate resistant 19 11574660-11579008 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002584, HPA057655, HPA059463 Uncertain Approved Cytosol Tissue enhanced 0 lung: 254.2 lymph node: 87.7 -DNAJC3 HP58, P58, P58IPK, PRKRI ENSG00000102580 DnaJ (Hsp40) homolog, subfamily C, member 3 13 95677139-95794989 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039336, HPA041326 Uncertain Approved Endoplasmic reticulum Expressed in all thyroid gland: 88.1 -UGGT2 FLJ10873, FLJ11485, HUGT2, MGC117360, MGC150689, MGC87276, UGCGL2 ENSG00000102595 UDP-glucose glycoprotein glucosyltransferase 2 13 95801580-96053482 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047955 Uncertain Mixed testis: 23.4 -ARHGEF7 BETA-PIX, COOL1, DKFZp686C12170, DKFZp761K1021, KIAA0142, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB ENSG00000102606 Rho guanine nucleotide exchange factor (GEF) 7 13 111114559-111305737 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004744 Approved Expressed in all cerebral cortex: 97.1 -FGF9 ENSG00000102678 Fibroblast growth factor 9 13 21671383-21704498 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB004392 Uncertain Tissue enhanced 0 kidney: 12.0 adrenal gland: 4.7 -SGCG A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE ENSG00000102683 Sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 13 23180952-23325165 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007476, HPA011922 Supported Supported Nucleoplasm Tissue enhanced 0 heart muscle: 70.1;skeletal muscle: 54.0 adipose tissue: 14.5 -PARP4 ADPRTL1, p193, VAULT3, VPARP, VWA5C ENSG00000102699 Poly (ADP-ribose) polymerase family, member 4 13 24420926-24512810 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011739 Approved Supported Cytosol Expressed in all gallbladder: 46.2 -SUPT20H bA421P11.4, C13orf19, FAM48A, P38IP, SPT20 ENSG00000102710 SPT20 homolog, SAGA complex component 13 37009312-37059713 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038906, HPA038907 Uncertain Supported Nucleoli fibrillar center Expressed in all testis: 99.5 -MRPS31 IMOGN38 ENSG00000102738 Mitochondrial ribosomal protein S31 13 40729135-40771173 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039083, HPA046344 Uncertain Supported Nucleoli
Mitochondria Expressed in all testis: 33.4 -SLC25A15 D13S327, HHH, ORC1, ORNT1 ENSG00000102743 Solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 13 40789412-40810111 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042146 Approved Expressed in all liver: 49.6 -KPNA3 hSRP1, IPOA4, SRP1gamma, SRP4 ENSG00000102753 Karyopherin alpha 3 (importin alpha 4) 13 49699307-49792921 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046852 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 49.6 -FLT1 FLT, VEGFR1 ENSG00000102755 Fms-related tyrosine kinase 1 13 28300344-28495128 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011740, HPA014290, CAB068189, CAB068190 Supported Supported Plasma membrane
Actin filaments Tissue enriched 8 placenta: 617.5 thyroid gland: 81.7 -RGCC bA157L14.2, C13orf15, RGC-32, RGC32 ENSG00000102760 Regulator of cell cycle 13 41457559-41470882 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035638, HPA063701 Approved Supported Nucleus
Nucleoli Expressed in all lung: 409.7 -VWA8 KIAA0564 ENSG00000102763 Von Willebrand factor A domain containing 8 13 41566837-41961120 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039075, HPA045478 Uncertain Approved Vesicles
Lipid droplets Expressed in all parathyroid gland: 21.3 -DGKH DGKeta ENSG00000102780 Diacylglycerol kinase, eta 13 42040036-42256578 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039533, HPA040355 Uncertain Mixed epididymis: 9.5 -KATNAL1 MGC2599 ENSG00000102781 Katanin p60 subunit A-like 1 13 30202630-30307484 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046205 Approved Uncertain Nucleoplasm
Cytosol Tissue enhanced 0 testis: 37.6 smooth muscle: 21.6 -INTS6 DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2 ENSG00000102786 Integrator complex subunit 6 13 51354077-51454264 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001552, HPA001846 Supported Supported Nucleoplasm
Actin filaments Expressed in all testis: 106.4 -IRG1 ENSG00000102794 Immunoresponsive 1 homolog (mouse) 13 76948497-76958642 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040143 Uncertain Tissue enriched 6 appendix: 2.0 lung: 0.3 -DHRS12 FLJ13639, SDR40C1 ENSG00000102796 Dehydrogenase/reductase (SDR family) member 12 13 51767993-51804157 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB034238, HPA057028, HPA058315 Uncertain Supported Nucleoplasm
Golgi apparatus
Vesicles Expressed in all epididymis: 22.6 -MEDAG AWMS3, C13orf33, FLJ14834, MEDA-4 ENSG00000102802 Mesenteric estrogen-dependent adipogenesis 13 30906191-30925572 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adipose tissue: 151.7 smooth muscle: 31.8 -TSC22D1 MGC17597, TGFB1I4, TSC22 ENSG00000102804 TSC22 domain family, member 1 13 44432143-44577147 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077414 Approved Nucleoplasm
Nuclear bodies Expressed in all prostate: 263.0 -CLN5 ENSG00000102805 Ceroid-lipofuscinosis, neuronal 5 13 76990660-77002517 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041788 Approved Expressed in all thyroid gland: 141.2 -OLFM4 GC1, GW112, OlfD ENSG00000102837 Olfactomedin 4 13 53028759-53052057 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 duodenum: 1226.8;rectum: 621.3;small intestine: 1466.5 colon: 454.6 -MSLN CAK1, MPF ENSG00000102854 Mesothelin 16 643262-768865 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002216, HPA017172 Supported Approved Nucleoplasm
Vesicles Group enriched 9 fallopian tube: 440.6;lung: 105.4 epididymis: 29.2 -MGRN1 KIAA0544, RNF156 ENSG00000102858 Mahogunin ring finger 1, E3 ubiquitin protein ligase 16 4616493-4690974 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007653 Approved Expressed in all cerebral cortex: 56.6 -ZNF629 KIAA0326, ZNF65 ENSG00000102870 Zinc finger protein 629 16 30778449-30787202 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019550, HPA056051 Uncertain Supported Nucleus
Golgi apparatus Expressed in all parathyroid gland: 27.4 -TRADD Hs.89862 ENSG00000102871 TNFRSF1A-associated via death domain 16 67154180-67160298 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004602 Approved Approved Cytosol Mixed spleen: 17.9 -HSF4 CTM ENSG00000102878 Heat shock transcription factor 4 16 67164681-67169945 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048584 Supported Nuclear speckles Mixed adrenal gland: 14.9 -CORO1A coronin-1, HCORO1, p57 ENSG00000102879 Coronin, actin binding protein, 1A 16 30182827-30189076 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046473, HPA051132 Supported Approved Cytosol Expressed in all lymph node: 601.3 -MAPK3 ERK1, p44erk1, p44mapk, PRKM3 ENSG00000102882 Mitogen-activated protein kinase 3 16 30114105-30123506 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002683, HPA003995, HPA005700, HPA030069 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 134.1 -GDPD3 MGC4171 ENSG00000102886 Glycerophosphodiester phosphodiesterase domain containing 3 16 30104810-30113856 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041148, HPA041470 Uncertain Approved Nucleoplasm
Cytokinetic bridge
Cytosol Mixed esophagus: 23.2 -ELMO3 CED-12, CED12, ELMO-3, FLJ13824 ENSG00000102890 Engulfment and cell motility 3 16 67199111-67204029 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021484 Approved Approved Plasma membrane
Cell Junctions Mixed skin: 39.4 -MT4 MTIV ENSG00000102891 Metallothionein 4 16 56565049-56568957 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 5 skin: 13.7 testis: 2.6 -PHKB ENSG00000102893 Phosphorylase kinase, beta 16 47461123-47701523 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA073380 Approved Golgi apparatus Expressed in all parathyroid gland: 97.5 -LYRM1 A211C6.1 ENSG00000102897 LYR motif containing 1 16 20899868-20925006 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA059840 Supported Nucleoplasm
Midbody Expressed in all testis: 70.0 -NUTF2 NTF2, PP15 ENSG00000102898 Nuclear transport factor 2 16 67846732-67872567 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040915, HPA040956 Supported Approved Microtubules Expressed in all smooth muscle: 82.6 -NUP93 KIAA0095 ENSG00000102900 Nucleoporin 93kDa 16 56730105-56850286 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017937 Uncertain Expressed in all testis: 74.3 -CENPT C16orf56, CENP-T, FLJ13111 ENSG00000102901 Centromere protein T 16 67828157-67847811 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041220, HPA058036 Approved Validated Nuclear bodies Expressed in all skin: 16.0 -TSNAXIP1 TXI1 ENSG00000102904 Translin-associated factor X interacting protein 1 16 67806765-67832148 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA053516 Approved Nucleus
Cytosol Group enriched 10 fallopian tube: 15.4;testis: 40.0 parathyroid gland: 2.7 -NFAT5 KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP ENSG00000102908 Nuclear factor of activated T-cells 5, tonicity-responsive 16 69565094-69704666 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057304, HPA069711 Approved Supported Nucleus
Cytosol Expressed in all parathyroid gland: 37.6 -LONP2 LONP, LONPL, MGC4840 ENSG00000102910 Lon peptidase 2, peroxisomal 16 48244296-48363122 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008862 Uncertain Expressed in all parathyroid gland: 79.5 -N4BP1 ENSG00000102921 NEDD4 binding protein 1 16 48538726-48620148 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040849, HPA041080 Approved Approved Nucleoli fibrillar center Expressed in all lung: 22.0 -CBLN1 ENSG00000102924 Cerebellin 1 precursor 16 49277917-49281831 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056335 Uncertain Endoplasmic reticulum Tissue enhanced 0 testis: 32.4 adipose tissue: 12.3 -ARL2BP BART, BART1, RP66 ENSG00000102931 ADP-ribosylation factor-like 2 binding protein 16 57245098-57253635 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043066, HPA048440 Approved Expressed in all testis: 95.4 -PLLP PMLP, TM4SF11 ENSG00000102934 Plasmolipin 16 57248547-57284687 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041862 Supported Expressed in all cerebral cortex: 118.4 -ZNF423 Ebfaz, JBTS19, KIAA0760, NPHP14, OAZ, Roaz, Zfp104 ENSG00000102935 Zinc finger protein 423 16 49487524-49857919 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015258, HPA065820 Uncertain Validated Nucleus Mixed fallopian tube: 15.2 -CCL22 A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1 ENSG00000102962 Chemokine (C-C motif) ligand 22 16 57358772-57366190 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 appendix: 19.2;tonsil: 14.1 skin: 7.9 -DHODH ENSG00000102967 Dihydroorotate dehydrogenase (quinone) 16 72008588-72027664 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010123, HPA011942 Approved Supported Nucleoplasm
Mitochondria Mixed liver: 23.7 -CCL17 ABCD-2, SCYA17, TARC ENSG00000102970 Chemokine (C-C motif) ligand 17 16 57404767-57416062 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002583 Approved Tissue enhanced 0 appendix: 11.5;lymph node: 10.1 tonsil: 5.6 -CTCF ENSG00000102974 CCCTC-binding factor (zinc finger protein) 16 67562407-67639183 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004122, CAB062550, CAB068181, CAB068182 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 57.7 -ACD Pip1, Ptop, Tint1, Tpp1 ENSG00000102977 Adrenocortical dysplasia homolog (mouse) 16 67657512-67660815 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049411, HPA057660 Approved Validated Nuclear bodies Mixed testis: 18.4 -POLR2C RPB3 ENSG00000102978 Polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 16 57462387-57472010 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040919, HPA041826 Approved Supported Nucleoplasm
Microtubules
Cytosol Expressed in all epididymis: 67.0 -PARD6A PAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40 ENSG00000102981 Par-6 family cell polarity regulator alpha 16 67660946-67662778 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB009733, HPA041551 Approved Supported Cell Junctions
Actin filaments
Cytosol Tissue enhanced 0 testis: 20.0 cerebral cortex: 12.1 -ZNF821 ENSG00000102984 Zinc finger protein 821 16 71859680-71895336 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA036372, HPA042742 Approved Supported Nucleoplasm
Nuclear speckles Tissue enhanced 0 testis: 33.3 cerebral cortex: 13.7 -MMP15 MT2-MMP, MTMMP2, SMCP-2 ENSG00000102996 Matrix metallopeptidase 15 (membrane-inserted) 16 58025566-58046901 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002611, HPA040390 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 thyroid gland: 69.9 duodenum: 39.8 -USB1 C16orf57, FLJ13154, HVSL1, Mpn1 ENSG00000103005 U6 snRNA biogenesis 1 16 57999546-58021618 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041791, HPA059854 Approved Supported Nucleus Expressed in all appendix: 38.5 -CYB5B CYB5-M ENSG00000103018 Cytochrome b5 type B (outer mitochondrial membrane) 16 69424525-69466266 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007893 Approved Approved Endoplasmic reticulum
Microtubule organizing center
Cytosol Expressed in all adrenal gland: 399.7 -CCDC113 DKFZp434N1418, HSPC065 ENSG00000103021 Coiled-coil domain containing 113 16 58231157-58283836 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA040759, HPA040869 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 fallopian tube: 49.6;testis: 32.7 parathyroid gland: 16.1 -PRSS54 CT67, FLJ25339, KLKBL4 ENSG00000103023 Protease, serine, 54 16 58279997-58295047 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041549 Uncertain Tissue enriched 264 testis: 62.8 fallopian tube: 0.2 -NME3 DR-nm23, NDPKC, NM23-H3 ENSG00000103024 NME/NM23 nucleoside diphosphate kinase 3 16 1770286-1771730 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041113, HPA052733 Approved Approved Nucleoplasm
Cytosol Expressed in all adrenal gland: 36.2 -NDRG4 KIAA1180, SMAP-8 ENSG00000103034 NDRG family member 4 16 58462846-58513628 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015313, HPA017587 Supported Uncertain Nucleus
Cytosol Tissue enhanced 0 adrenal gland: 147.3;cerebral cortex: 421.4 heart muscle: 140.8 -PSMD7 MOV34, P40, Rpn8, S12 ENSG00000103035 Proteasome 26S subunit, non-ATPase 7 16 74296775-74306288 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019379, HPA049824, HPA056069 Approved Validated Nucleoplasm Expressed in all prostate: 109.5 -SETD6 FLJ21148 ENSG00000103037 SET domain containing 6 16 58515479-58521181 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041481, HPA053546 Uncertain Supported Nucleus
Cytosol Expressed in all parathyroid gland: 21.3 -SLC38A7 FLJ10815 ENSG00000103042 Solute carrier family 38, member 7 16 58665109-58685104 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041777 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Mixed testis: 34.8 -VAC14 ArPIKfyve, FLJ10305, TAX1BP2 ENSG00000103043 Vac14 homolog (S. cerevisiae) 16 70687439-70801161 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027766 Approved Approved Vesicles
Cytosol Expressed in all parathyroid gland: 31.0 -HAS3 ENSG00000103044 Hyaluronan synthase 3 16 69105564-69118719 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031554, CAB033850 Supported Approved Microtubules Tissue enhanced 0 lung: 29.9;urinary bladder: 37.7 stomach: 12.1 -TANGO6 FLJ12688, KIAA1746, TMCO7 ENSG00000103047 Transport and golgi organization 6 homolog 16 68843604-69085180 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041312 Approved Approved Golgi apparatus
Cytosol Mixed parathyroid gland: 14.9 -COG4 COD1, DKFZP586E1519 ENSG00000103051 Component of oligomeric golgi complex 4 16 70480568-70523565 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA040924, HPA042539 Approved Approved Golgi apparatus
Vesicles Expressed in all parathyroid gland: 47.6 -SMPD3 NSMASE2 ENSG00000103056 Sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 16 68358325-68448688 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033885, HPA065535, HPA069383 Approved Supported Endoplasmic reticulum Tissue enhanced 0 duodenum: 62.7;small intestine: 64.1 stomach: 22.9 -SLC7A6OS FLJ13291 ENSG00000103061 Solute carrier family 7, member 6 opposite strand 16 68284503-68310951 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041533 Approved Approved Nucleoplasm
Cytosol Expressed in all lymph node: 19.3 -SLC7A6 KIAA0245, LAT-2, LAT3, y+LAT-2 ENSG00000103064 Solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 16 68264516-68301823 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050713 Uncertain Approved Vesicles
Plasma membrane Mixed adipose tissue: 35.1 -PLA2G15 GXVPLA2, LLPL, LYPLA3 ENSG00000103066 Phospholipase A2, group XV 16 68245304-68261062 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041702, HPA041727 Supported Approved Nucleoplasm
Vesicles Expressed in all placenta: 37.3 -ESRP2 FLJ21918, RBM35B ENSG00000103067 Epithelial splicing regulatory protein 2 16 68229111-68238102 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040751, HPA048597, HPA048618 Uncertain Validated Nucleoplasm Mixed skin: 37.2 -FA2H FAAH, FAXDC1, FLJ25287, SPG35 ENSG00000103089 Fatty acid 2-hydroxylase 16 74712955-74774831 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056614, HPA077840 Approved Approved Nuclear membrane Tissue enhanced 0 cerebral cortex: 51.7;stomach: 57.9 gallbladder: 28.7 -WDR59 FLJ12270 ENSG00000103091 WD repeat domain 59 16 74871367-75000173 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041084, HPA048218 Approved Approved Cytosol Expressed in all parathyroid gland: 43.0 -MON1B HSRG1, KIAA0872, SAND2 ENSG00000103111 MON1 secretory trafficking family member B 16 77190835-77202405 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046285 Approved Approved Cytosol Expressed in all thyroid gland: 30.2 -CMC2 C16orf61, DC13, MGC45036 ENSG00000103121 C-x(9)-C motif containing 2 16 80966448-81020270 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006871, CAB026396 Approved Supported Mitochondria Expressed in all testis: 84.4 -AXIN1 PPP1R49 ENSG00000103126 Axin 1 16 287440-352673 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012987 Approved Supported Nucleoli
Vesicles Expressed in all spleen: 15.8 -HCFC1R1 FLJ20568, HPIP ENSG00000103145 Host cell factor C1 regulator 1 (XPO1 dependent) 16 3022620-3024286 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059647 Approved Approved Nucleoplasm Expressed in all skeletal muscle: 184.4 -NPRL3 C16orf35, CGTHBA, HS-40, MARE, NPR3, RMD11 ENSG00000103148 NPR3-like, GATOR1 complex subunit 16 84271-138860 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011741 Uncertain Approved Cytosol Expressed in all parathyroid gland: 24.5 -MLYCD hMCD, MCD ENSG00000103150 Malonyl-CoA decarboxylase 16 83899126-83927026 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031625 Approved Mixed heart muscle: 3.2 -MPG MDG ENSG00000103152 N-methylpurine DNA glycosylase 16 77007-85853 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006531 Approved Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 48.9 -NECAB2 EFCBP2 ENSG00000103154 N-terminal EF-hand calcium binding protein 2 16 83968632-84002776 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013998, HPA014144, CAB068211 Supported Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 46.9 kidney: 10.5 -HSDL1 SDR12C3 ENSG00000103160 Hydroxysteroid dehydrogenase like 1 16 84122146-84145192 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045745 Supported Mitochondria Expressed in all thyroid gland: 45.6 -TAF1C MGC:39976, SL1, TAFI110, TAFI95 ENSG00000103168 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 16 84177847-84187070 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072229 Supported Nucleoli fibrillar center Expressed in all spleen: 15.6 -NAGPA APAA, UCE ENSG00000103174 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 16 5024844-5034141 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064055 Approved Mixed cerebral cortex: 9.6 -WFDC1 PS20 ENSG00000103175 WAP four-disulfide core domain 1 16 84294646-84329851 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA031411 Uncertain Tissue enhanced 0 placenta: 120.9;seminal vesicle: 134.0 prostate: 85.3 -SEC14L5 KIAA0420, PRELID4B ENSG00000103184 SEC14-like lipid binding 5 16 4958317-5019158 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041492, HPA041825 Uncertain Uncertain Golgi apparatus
Cytosol Tissue enriched 7 cerebral cortex: 17.2 heart muscle: 2.4 -COTL1 CLP ENSG00000103187 Coactosin-like F-actin binding protein 1 16 84565594-84618077 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008918 Supported Expressed in all lymph node: 427.6 -USP10 KIAA0190, UBPO ENSG00000103194 Ubiquitin specific peptidase 10 16 84699978-84779922 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006731, HPA006749 Approved Validated Nucleoplasm
Cytosol Expressed in all parathyroid gland: 61.9 -CRISPLD2 DKFZP434B044, LCRISP2 ENSG00000103196 Cysteine-rich secretory protein LCCL domain containing 2 16 84819984-84920768 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030055 Approved Approved Nucleoplasm
Cytosol Expressed in all placenta: 173.0 -TSC2 LAM, PPP1R160, TSC4, tuberin ENSG00000103197 Tuberous sclerosis 2 16 2047465-2088720 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002225, HPA030409, HPA049679 Approved Validated Cytosol Expressed in all seminal vesicle: 35.7 -ZNF500 KIAA0557, ZKSCAN18, ZSCAN50 ENSG00000103199 Zinc finger protein 500 16 4748239-4767624 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA035498, HPA057963 Supported Validated Nucleoplasm
Cytosol Mixed testis: 8.2 -NME4 NDPKD, nm23-H4, NM23H4 ENSG00000103202 NME/NM23 nucleoside diphosphate kinase 4 16 396725-410367 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045997, HPA072588 Approved Supported Mitochondria Expressed in all prostate: 161.0 -ABCC1 GS-X, MRP, MRP1 ENSG00000103222 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 16 15949577-16143074 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002380 Uncertain Supported Plasma membrane Mixed parathyroid gland: 18.1 -NOMO3 ENSG00000103226 NODAL modulator 3 16 16232495-16294814 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level No evidence HPA046697, HPA061174 Approved Mixed skin: 1.9 -LMF1 C16orf26, FLJ12681, FLJ22302, JFP11, TMEM112, TMEM112A ENSG00000103227 Lipase maturation factor 1 16 853634-981318 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 22.7 -FOXF1 FKHL5, FREAC1 ENSG00000103241 Forkhead box F1 16 86510527-86515418 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028886 Approved Nucleoplasm Mixed placenta: 32.8 -NARFL FLJ21988, HPRN, IOP1, PRN ENSG00000103245 Nuclear prelamin A recognition factor-like 16 729753-741329 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040851 Approved Approved Plasma membrane
Cytosol Expressed in all cerebral cortex: 19.4 -MTHFSD FLJ12998 ENSG00000103248 Methenyltetrahydrofolate synthetase domain containing 16 86530176-86555235 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041333 Uncertain Approved Nucleus
Vesicles Expressed in all testis: 33.1 -CLCN7 CLC-7, CLC7, OPTA2, PPP1R63 ENSG00000103249 Chloride channel, voltage-sensitive 7 16 1444934-1475580 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043019, HPA043586 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 40.4 -HAGHL MGC2605 ENSG00000103253 Hydroxyacylglutathione hydrolase-like 16 726936-735525 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 9.1 spleen: 4.5 -FAM173A C16orf24, MGC2494 ENSG00000103254 Family with sequence similarity 173, member A 16 720581-722601 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046262 Approved Approved Cytosol Mixed spleen: 9.5 -SLC7A5 CD98, D16S469E, E16, LAT1, MPE16 ENSG00000103257 Solute carrier family 7 (amino acid transporter light chain, L system), member 5 16 87830023-87869488 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052673, HPA056077 Approved Supported Vesicles
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 90.5;testis: 84.4 bone marrow: 66.3 -METRN C16orf23, MGC2601 ENSG00000103260 Meteorin, glial cell differentiation regulator 16 715115-719655 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051164 Approved Approved Nucleoplasm
Nuclear membrane
Cytosol Tissue enhanced 0 cerebral cortex: 64.9 fallopian tube: 37.8 -FBXO31 FBX14, Fbx31, FBXO14, MGC15419 ENSG00000103264 F-box protein 31 16 87326987-87392142 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030150 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all cerebral cortex: 23.9 -STUB1 CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1 ENSG00000103266 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 16 680224-682870 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037202, CAB037209, HPA041222, HPA043531 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 138.1 -RHBDL1 RHBDL, RRP ENSG00000103269 Rhomboid, veinlet-like 1 (Drosophila) 16 675666-678268 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA030359, HPA030360, HPA046593 Uncertain Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 8.0 adrenal gland: 3.3 -NUBP1 NBP1, NBP35 ENSG00000103274 Nucleotide binding protein 1 16 10743786-10769351 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041656, HPA041799 Supported Supported Cytosol Expressed in all parathyroid gland: 54.3 -UBE2I UBC9 ENSG00000103275 Ubiquitin-conjugating enzyme E2I 16 1308880-1327018 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003909, CAB009021 Approved Validated Cytosol Expressed in all ovary: 116.8 -ZP2 ZPA ENSG00000103310 Zona pellucida glycoprotein 2 (sperm receptor) 16 21197450-21214510 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA011296 Approved Not detected placenta: 0.7 -MEFV FMF, MEF, TRIM20 ENSG00000103313 Mediterranean fever 16 3242028-3256627 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 8.3;spleen: 7.2 bone marrow: 4.2 -CRYM DFNA40 ENSG00000103316 Crystallin, mu 16 21238874-21303083 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019086, HPA030619 Supported Supported Cytosol Group enriched 6 cerebral cortex: 102.6;heart muscle: 98.1;kidney: 56.5;prostate: 52.7;urinary bladder: 30.8 lung: 11.5 -EEF2K eEF-2K ENSG00000103319 Eukaryotic elongation factor 2 kinase 16 22206282-22288732 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007818, HPA056061 Approved Approved Nucleoplasm Expressed in all skin: 57.5 -CAPN15 SOLH ENSG00000103326 Calpain 15 16 527717-554636 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011960 Uncertain Approved Nucleus Mixed small intestine: 17.3 -PIEZO1 FAM38A, KIAA0233 ENSG00000103335 Piezo-type mechanosensitive ion channel component 1 16 88715343-88785211 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047185 Uncertain Mixed adipose tissue: 42.0 -GSPT1 eRF3a, ETF3A, GST1 ENSG00000103342 G1 to S phase transition 1 16 11868128-11916082 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052488 Approved Approved Vesicles
Cytosol Expressed in all parathyroid gland: 130.4 -ZNF174 ZSCAN8 ENSG00000103343 Zinc finger protein 174 16 3401235-3409370 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009656 Approved Supported Nucleoplasm
Actin filaments
Cytosol Expressed in all parathyroid gland: 27.7 -CLUAP1 CFAP22, FAP22, FLJ13297, IFT38, KIAA0643 ENSG00000103351 Clusterin associated protein 1 16 3500924-3539048 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036976, HPA044191 Uncertain Supported Nucleoplasm
Vesicles Expressed in all testis: 71.7 -UBFD1 FLJ38870, FLJ42145, UBPH ENSG00000103353 Ubiquitin family domain containing 1 16 23557362-23574389 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051746 Approved Nucleus
Nucleoli Expressed in all parathyroid gland: 55.5 -PRSS33 EOS ENSG00000103355 Protease, serine, 33 16 2783953-2787948 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058082 Uncertain Tissue enriched 7 fallopian tube: 7.4 small intestine: 1.0 -EARS2 KIAA1970, MSE1 ENSG00000103356 Glutamyl-tRNA synthetase 2, mitochondrial 16 23522014-23557731 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043289, HPA043633 Approved Supported Nucleoplasm
Mitochondria Expressed in all parathyroid gland: 32.3 -TCEB2 SIII ENSG00000103363 Transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 16 2771414-2777297 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all fallopian tube: 350.8 -GGA2 KIAA1080, VEAR ENSG00000103365 Golgi-associated, gamma adaptin ear containing, ARF binding protein 2 16 23463542-23521995 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034422, HPA043313, HPA063634 Approved Validated Golgi apparatus Expressed in all lymph node: 88.1 -AQP8 ENSG00000103375 Aquaporin 8 16 25215731-25228940 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046259 Approved Group enriched 132 colon: 325.1;pancreas: 269.4;rectum: 169.2 smooth muscle: 1.9 -CPPED1 CSTP1, FLJ11151 ENSG00000103381 Calcineurin-like phosphoesterase domain containing 1 16 12659799-12804017 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040938, HPA041970 Uncertain Supported Plasma membrane
Cytosol Expressed in all spleen: 41.6 -USP31 KIAA1203 ENSG00000103404 Ubiquitin specific peptidase 31 16 23061406-23149270 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA006937 Uncertain Approved Cytosol Mixed testis: 22.2 -HMOX2 HO-2 ENSG00000103415 Heme oxygenase 2 16 4474690-4510347 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025464, HPA040611 Supported Approved Vesicles
Cytosol Expressed in all testis: 97.3 -DNAJA3 hTid-1, TID1 ENSG00000103423 DnaJ (Hsp40) homolog, subfamily A, member 3 16 4425805-4456775 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016095, HPA040875, HPA044229 Approved Supported Mitochondria Expressed in all parathyroid gland: 24.8 -CORO7-PAM16 ENSG00000103426 CORO7-PAM16 readthrough 16 4340251-4420494 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA041657, HPA053586, HPA062721 Uncertain Approved Nucleoplasm
Microtubules
Mitochondria Not detected testis: 0.2 -BFAR BAR, RNF47 ENSG00000103429 Bifunctional apoptosis regulator 16 14632815-14669236 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all placenta: 23.3 -SALL1 Hsal1, TBS, ZNF794 ENSG00000103449 Spalt-like transcription factor 1 16 51135975-51151367 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049829 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 thyroid gland: 40.0 cerebral cortex: 30.4 -TOX3 CAGF9, TNRC9 ENSG00000103460 TOX high mobility group box family member 3 16 52438005-52547802 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA040376 Approved Approved Nucleoplasm Mixed stomach: 18.0 -RBL2 p130, Rb2 ENSG00000103479 Retinoblastoma-like 2 16 53433977-53491649 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016547, HPA019703 Supported Approved Nucleus
Nucleoli
Cytosol Expressed in all parathyroid gland: 158.3 -QPRT QPRTase ENSG00000103485 Quinolinate phosphoribosyltransferase 16 29679008-29698699 Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011887 Approved Expressed in all kidney: 111.8 -XYLT1 PXYLT1, XT-I ENSG00000103489 Xylosyltransferase I 16 17101769-17470881 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007478, HPA007966 Approved Approved Endoplasmic reticulum Mixed cervix: 12.2 -PYCARD ASC, CARD5, TMS-1 ENSG00000103490 PYD and CARD domain containing 16 31201485-31203450 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006853, CAB015948, HPA049074, HPA054496 Supported Supported Nucleus
Nucleoli
Cytosol Mixed duodenum: 52.9 -RPGRIP1L CORS3, FTM, JBTS7, KIAA1005, MKS5, NPHP8, PPP1R134 ENSG00000103494 RPGRIP1-like 16 53597683-53703938 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039405, HPA040530 Uncertain Approved Plasma membrane
Cytosol Tissue enhanced 0 testis: 27.8 parathyroid gland: 19.1 -MAZ Pur-1, ZF87, Zif87, ZNF801 ENSG00000103495 MYC-associated zinc finger protein (purine-binding transcription factor) 16 29806106-29811164 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048315, HPA059495, HPA065930 Approved Supported Nucleus Expressed in all prostate: 195.5 -STX4 p35-2, STX4A ENSG00000103496 Syntaxin 4 16 31032889-31042975 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001330 Approved Validated Plasma membrane Expressed in all parathyroid gland: 63.4 -CDIPT PIS, PIS1 ENSG00000103502 CDP-diacylglycerol--inositol 3-phosphatidyltransferase 16 29858357-29863736 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056597 Approved Approved Nucleoplasm
Nuclear membrane
Plasma membrane Expressed in all parathyroid gland: 110.5 -BCKDK ENSG00000103507 Branched chain ketoacid dehydrogenase kinase 16 31106107-31112791 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017995, HPA056067 Supported Supported Mitochondria Expressed in all parathyroid gland: 33.6 -KAT8 FLJ14040, hMOF, MOF, MYST1, ZC2HC8 ENSG00000103510 K(lysine) acetyltransferase 8 16 31115754-31131393 Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066324 Supported Nucleoplasm Expressed in all ovary: 61.5 -NOMO1 PM5 ENSG00000103512 NODAL modulator 1 16 14833681-14896160 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB025192, HPA046697, HPA061174 Approved Approved Endoplasmic reticulum Mixed thyroid gland: 11.8 -IL21R CD360 ENSG00000103522 Interleukin 21 receptor 16 27402162-27452042 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042296 Uncertain Uncertain Plasma membrane
Cytosol Tissue enhanced 0 appendix: 16.4;lymph node: 29.2;tonsil: 18.0 spleen: 7.7 -SYT17 ENSG00000103528 Synaptotagmin XVII 16 19167971-19268334 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040811, HPA042059 Approved Approved Nucleus
Cytosol Tissue enhanced 0 cerebral cortex: 39.9;parathyroid gland: 32.0 prostate: 14.6 -TMC5 FLJ13593 ENSG00000103534 Transmembrane channel-like 5 16 19410496-19499113 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040810, HPA042037 Approved Approved Nucleus
Plasma membrane Tissue enhanced 0 small intestine: 60.2 duodenum: 46.6 -CCP110 CP110, KIAA0419 ENSG00000103540 Centriolar coiled coil protein 110kDa 16 19523811-19553408 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039402 Approved Supported Centrosome Tissue enhanced 0 testis: 65.0 cerebral cortex: 29.8 -C16orf62 MGC16824 ENSG00000103544 Chromosome 16 open reading frame 62 16 19555240-19706793 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042969, HPA053547 Uncertain Approved Mitochondria Expressed in all parathyroid gland: 68.5 -SLC6A2 NAT1, NET, NET1, SLC6A5 ENSG00000103546 Solute carrier family 6 (neurotransmitter transporter), member 2 16 55655604-55706192 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004057, CAB078195 Supported Supported Approved Mitochondria
Cytosol Tissue enhanced 0 adrenal gland: 29.4;placenta: 18.2;skin: 15.7 testis: 11.4 -RNF40 BRE1B, KIAA0661, RBP95, STARING ENSG00000103549 Ring finger protein 40, E3 ubiquitin protein ligase 16 30761745-30776307 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041330, HPA054227 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 77.4 -KNOP1 101F10.1, C16orf88, FAM191A, TSG118 ENSG00000103550 Lysine-rich nucleolar protein 1 16 19701934-19718235 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041079, HPA066169 Uncertain Supported Nucleoli
Cytosol Expressed in all parathyroid gland: 23.0 -AQP9 HsT17287, SSC1 ENSG00000103569 Aquaporin 9 15 58138169-58185911 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 appendix: 104.4;liver: 352.6 epididymis: 49.4 -AAGAB FLJ11506, p34 ENSG00000103591 Alpha- and gamma-adaptin binding protein 15 67201033-67255195 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039371, HPA040174 Supported Supported Nuclear speckles
Cytosol Expressed in all thyroid gland: 55.4 -IQCH FLJ12476 ENSG00000103599 IQ motif containing H 15 67254800-67502260 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040845 Uncertain Approved Cytosol Tissue enhanced 0 fallopian tube: 10.7;testis: 21.0 thyroid gland: 6.9 -LACTB FLJ14902, MRPL56 ENSG00000103642 Lactamase, beta 15 63121800-63142061 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036361, HPA036362 Supported Supported Mitochondria Expressed in all testis: 39.6 -CORO2B ClipinC, KIAA0925 ENSG00000103647 Coronin, actin binding protein, 2B 15 68578969-68727806 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017960 Approved Approved Plasma membrane
Focal adhesion sites Tissue enhanced 0 cerebral cortex: 73.5;fallopian tube: 36.2 ovary: 17.8 -CSK ENSG00000103653 C-src tyrosine kinase 15 74782057-74803198 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011203, HPA026488, HPA028425 Approved Approved Vesicles
Cytosol Expressed in all lymph node: 197.7 -HERC1 p532, p619 ENSG00000103657 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 15 63608618-63833942 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049749 Uncertain Expressed in all parathyroid gland: 57.5 -TRIP4 HsT17391, ZC2HC5 ENSG00000103671 Thyroid hormone receptor interactor 4 15 64387748-64455303 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016605, HPA050666 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all thyroid gland: 42.0 -MTFMT FMT1 ENSG00000103707 Mitochondrial methionyl-tRNA formyltransferase 15 65001512-65029639 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040710 Uncertain Approved Nucleoplasm
Cytosol Mixed smooth muscle: 2.8 -RASL12 RIS ENSG00000103710 RAS-like, family 12 15 65053337-65076690 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 seminal vesicle: 100.6 prostate: 61.2 -AP3B2 NAPTB ENSG00000103723 Adaptor-related protein complex 3, beta 2 subunit 15 82659281-82709914 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039467, HPA039818 Supported Uncertain Nucleoplasm
Golgi apparatus
Cytosol Group enriched 6 cerebral cortex: 36.3;parathyroid gland: 7.5 adrenal gland: 3.8 -ACSBG1 BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352 ENSG00000103740 Acyl-CoA synthetase bubblegum family member 1 15 78167468-78245688 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041642, CAB045955, HPA058869 Approved Approved Vesicles Tissue enhanced 0 cerebral cortex: 25.7;skin: 13.3 adrenal gland: 8.1 -IGDCC4 LOC57722, NOPE ENSG00000103742 Immunoglobulin superfamily, DCC subclass, member 4 15 65381464-65423072 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008510, HPA008576 Approved Approved Approved Nucleoplasm
Cytosol Mixed ovary: 8.9 -RAB11A YL8 ENSG00000103769 RAB11A, member RAS oncogene family 15 65726054-65891991 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013097, HPA051697, HPA060686 Approved Supported Microtubule organizing center Expressed in all esophagus: 526.8 -CTSH ACC-4, ACC-5, ACC4, ACC5, CPSB ENSG00000103811 Cathepsin H 15 78921058-78949574 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000458, HPA003524 Supported Supported Vesicles
Cytosol
Cytoplasmic bodies Expressed in all lung: 570.4 -TTC23 FLJ12572, HCC-8 ENSG00000103852 Tetratricopeptide repeat domain 23 15 99136323-99251223 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039806, HPA040369 Uncertain Approved Plasma membrane
Cytosol Mixed testis: 24.2 -CD276 B7-H3, B7H3, B7RP-2 ENSG00000103855 CD276 molecule 15 73683966-73714518 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009285, HPA017139, CAB017826 Approved Approved Vesicles Mixed placenta: 30.1 -FAH ENSG00000103876 Fumarylacetoacetate hydrolase (fumarylacetoacetase) 15 80152490-80186946 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041370, HPA044093 Supported Approved Cytosol Expressed in all liver: 151.5 -CEMIP IR2155535, KIAA1199, TMEM2L ENSG00000103888 Cell migration inducing protein, hyaluronan binding 15 80779343-80951776 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 endometrium: 54.5 epididymis: 17.0 -RPAP1 DKFZP727M111, FLJ12732, KIAA1403, MGC858 ENSG00000103932 RNA polymerase II associated protein 1 15 41517176-41544269 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041739 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 13.1 -HOMER2 CPD, Cupidin, HOMER-2, HOMER-2A, HOMER-2B, Vesl-2 ENSG00000103942 Homer scaffolding protein 2 15 82836946-82986153 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040134 Uncertain Supported Cytosol Expressed in all prostate: 90.8 -EHD4 PAST4 ENSG00000103966 EH-domain containing 4 15 41895939-41972578 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049890, HPA049986, HPA052729, HPA066751 Approved Approved Plasma membrane Expressed in all gallbladder: 37.2 -TMEM87A DKFZP564G2022 ENSG00000103978 Transmembrane protein 87A 15 42210452-42273663 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018104, HPA018189 Supported Supported Golgi apparatus Expressed in all prostate: 122.4 -ZNF106 SH3BP3, ZFP106, ZNF474 ENSG00000103994 Zinc finger protein 106 15 42412823-42491123 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054267 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all skeletal muscle: 144.2 -CEP152 KIAA0912, MCPH4, SCKL5 ENSG00000103995 Centrosomal protein 152kDa 15 48712928-48811146 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039408 Approved Supported Centrosome Tissue enhanced 0 testis: 18.0 bone marrow: 10.3 -ATP8B4 ATPIM, KIAA1939 ENSG00000104043 ATPase, class I, type 8B, member 4 15 49858238-50182817 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040254 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 bone marrow: 23.1 endometrium: 9.2 -OCA2 BEY, BEY1, BEY2, D15S12, EYCL, EYCL2, EYCL3, P ENSG00000104044 Oculocutaneous albinism II 15 27754875-28099358 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skin: 7.5;thyroid gland: 5.8 testis: 2.5 -DTWD1 MDS009, MGC111207 ENSG00000104047 DTW domain containing 1 15 49620980-49656232 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042214 Uncertain Approved Nucleus
Nucleoli
Vesicles Expressed in all endometrium: 39.5 -TGM5 TGX ENSG00000104055 Transglutaminase 5 15 43232595-43266857 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 7 esophagus: 8.4;skin: 22.5 tonsil: 2.3 -FAM189A1 KIAA0574, TMEM228 ENSG00000104059 Family with sequence similarity 189, member A1 15 29120254-29570723 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA009410, HPA010637 Uncertain Supported Nucleus Tissue enhanced 0 cerebral cortex: 2.2;parathyroid gland: 2.0 testis: 0.8 -GABPB1 E4TF1-47, GABPB, GABPB2 ENSG00000104064 GA binding protein transcription factor, beta subunit 1 15 50275392-50355408 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019653, HPA067444 Supported Supported Nucleoplasm
Cytoplasmic bodies Expressed in all testis: 28.7 -TJP1 DKFZp686M05161, MGC133289, ZO-1 ENSG00000104067 Tight junction protein 1 15 29699367-29968865 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001636, HPA001637, CAB010822 Supported Validated Cell Junctions Mixed cerebral cortex: 49.8 -BMF FLJ00065 ENSG00000104081 Bcl2 modifying factor 15 40087890-40108892 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA010120 Approved Approved Nucleoplasm Mixed endometrium: 25.9 -DMXL2 KIAA0856, RC3 ENSG00000104093 Dmx-like 2 15 51447711-51622833 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039375 Approved Mixed cerebral cortex: 26.2 -SCG3 FLJ90833, SgIII ENSG00000104112 Secretogranin III 15 51681353-51721031 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006880, CAB033274, HPA053715 Supported Approved Validated Vesicles Tissue enriched 13 cerebral cortex: 279.1 adrenal gland: 22.0 -DNAJC17 FLJ10634 ENSG00000104129 DnaJ (Hsp40) homolog, subfamily C, member 17 15 40765155-40807478 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040914, HPA041187 Approved Approved Nucleoplasm Expressed in all endometrium: 24.2 -EIF3J eIF3-alpha, eIF3-p35, eIF3j, EIF3S1 ENSG00000104131 Eukaryotic translation initiation factor 3, subunit J 15 44537057-44563029 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050977 Approved Validated Cytosol Expressed in all skeletal muscle: 69.3 -SPG11 FLJ21439, KIAA1840 ENSG00000104133 Spastic paraplegia 11 (autosomal recessive) 15 44562696-44663678 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040412, HPA040947 Approved Supported Nucleoli
Plasma membrane
Cytosol Expressed in all parathyroid gland: 49.0 -RHOV ARHV, Chp, WRCH2 ENSG00000104140 Ras homolog family member V 15 40872214-40874289 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA053343 Supported Tissue enhanced 0 esophagus: 71.8;skin: 72.8 tonsil: 21.0 -VPS18 KIAA1475, PEP3 ENSG00000104142 Vacuolar protein sorting 18 homolog (S. cerevisiae) 15 40894430-40903975 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040701 Approved Expressed in all cerebral cortex: 15.9 -OIP5 CT86, hMIS18beta, MIS18B ENSG00000104147 Opa interacting protein 5 15 41309268-41332621 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052271, HPA059602 Approved Supported Nucleoplasm Tissue enriched 5 testis: 37.2 lymph node: 6.8 -SLC30A4 ZNT4 ENSG00000104154 Solute carrier family 30 (zinc transporter), member 4 15 45479611-45522807 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA018178 Uncertain Tissue enriched 5 prostate: 64.1 testis: 11.8 -BLOC1S6 HPS9, PA, PLDN ENSG00000104164 Biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 15 45587123-45615999 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039928 Approved Expressed in all thyroid gland: 83.6 -MYEF2 FLJ11213, HsT18564, KIAA1341, MEF-2 ENSG00000104177 Myelin expression factor 2 15 48134631-48178517 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA004883 Supported Supported Nucleoplasm Tissue enhanced 0 testis: 51.1 cerebral cortex: 47.3 -SGK3 SGK2, SGKL ENSG00000104205 Serum/glucocorticoid regulated kinase family, member 3 8 66712418-66862022 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027146 Supported Expressed in all parathyroid gland: 47.7 -PDGFRL PRLTS ENSG00000104213 Platelet-derived growth factor receptor-like 8 17576433-17644071 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052801 Approved Nucleus
Nucleoli
Golgi apparatus Mixed breast: 48.9 -CSPP1 CSPP, FLJ22490, JBTS21 ENSG00000104218 Centrosome and spindle pole associated protein 1 8 67062426-67196263 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056174 Supported Microtubule organizing center Expressed in all testis: 34.8 -ZDHHC2 ZNF372 ENSG00000104219 Zinc finger, DHHC-type containing 2 8 17156029-17224799 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023331 Uncertain Expressed in all thyroid gland: 53.5 -BRF2 BRFU, FLJ11052, TFIIIB50 ENSG00000104221 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 8 37843268-37849904 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB019269, HPA023378 Supported Approved Nucleoli Expressed in all epididymis: 18.6 -TRIM35 HLS5, KIAA1098, MAIR ENSG00000104228 Tripartite motif containing 35 8 27284887-27311319 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019647 Uncertain Approved Nucleoplasm Expressed in all skin: 14.6 -ZFAND1 FLJ14007 ENSG00000104231 Zinc finger, AN1-type domain 1 8 81701334-81732903 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023383 Approved Approved Centrosome
Cytosol Expressed in all thyroid gland: 92.2 -RP1 DCDC4A ENSG00000104237 Retinitis pigmentosa 1 (autosomal dominant) 8 54616067-54630834 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042257 Supported Tissue enhanced 0 fallopian tube: 2.1 lung: 0.6 -CA2 CA-II, CAII, Car2 ENSG00000104267 Carbonic anhydrase II 8 85463852-85481493 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001550, CAB010102 Supported Tissue enhanced 0 colon: 613.9;rectum: 636.0;stomach: 922.7 kidney: 305.6 -FZD3 ENSG00000104290 Frizzled class receptor 3 8 28494205-28574268 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB024995, HPA042320 Approved Approved Nucleoplasm
Vesicles Mixed cerebral cortex: 16.5 -INTS9 CPSF2L, FLJ10871, RC-74 ENSG00000104299 Integrator complex subunit 9 8 28767661-28890242 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051615, HPA066822 Validated Nucleoplasm Expressed in all testis: 19.8 -RIPK2 CARD3, CARDIAK, RICK, RIP2 ENSG00000104312 Receptor-interacting serine-threonine kinase 2 8 89757747-89791063 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015273, HPA016499 Approved Validated Cytosol Mixed gallbladder: 14.0 -EYA1 BOR ENSG00000104313 EYA transcriptional coactivator and phosphatase 1 8 71197433-71362232 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028917 Supported Nucleoplasm
Nuclear bodies Tissue enhanced 0 parathyroid gland: 80.2 prostate: 19.5 -NBN AT-V1, AT-V2, ATV, NBS, NBS1 ENSG00000104320 Nibrin 8 89933336-90003228 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001429, CAB003836 Supported Approved Nucleoplasm
Golgi apparatus Expressed in all appendix: 38.1 -TRPA1 ANKTM1 ENSG00000104321 Transient receptor potential cation channel, subfamily A, member 1 8 72019917-72075617 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026630 Uncertain Tissue enhanced 0 urinary bladder: 30.5 gallbladder: 11.4 -CPQ LDP, PGCP ENSG00000104324 Carboxypeptidase Q 8 96645227-97149654 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023235, HPA024490 Supported Approved Golgi apparatus
Vesicles Expressed in all thyroid gland: 380.7 -DECR1 DECR, SDR18C1 ENSG00000104325 2,4-dienoyl CoA reductase 1, mitochondrial 8 90001405-90052092 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023160, HPA023162, HPA023238 Supported Supported Mitochondria
Cytosol Expressed in all liver: 262.7 -CALB1 CALB ENSG00000104327 Calbindin 1, 28kDa 8 90058608-90095475 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002138, HPA023099, HPA056734 Supported Supported Vesicles Tissue enriched 14 kidney: 337.3 cerebral cortex: 24.8 -IMPAD1 FLJ20421, gPAPP, IMPA3 ENSG00000104331 Inositol monophosphatase domain containing 1 8 56957933-56993844 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009411 Supported Supported Nucleus
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 51.8 -SFRP1 FRP, FRP-1, SARP2 ENSG00000104332 Secreted frizzled-related protein 1 8 41261958-41309497 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008116, HPA064870 Approved Approved Nucleoli
Cytosol Tissue enhanced 0 breast: 356.5;cervix, uterine: 323.1 endometrium: 229.7 -LAPTM4B LC27 ENSG00000104341 Lysosomal protein transmembrane 4 beta 8 97775057-97853013 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level CAB020782, HPA068830 Uncertain Approved Golgi apparatus Expressed in all heart muscle: 134.9 -UBE2W FLJ11011 ENSG00000104343 Ubiquitin-conjugating enzyme E2W (putative) 8 73780097-73878910 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045161, HPA073181 Uncertain Supported Nucleoli Expressed in all testis: 19.7 -POP1 ENSG00000104356 POP1 homolog, ribonuclease P/MRP subunit 8 98117297-98159834 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060020 Supported Nucleoli Mixed testis: 6.0 -NIPAL2 FLJ13955, NPAL2 ENSG00000104361 NIPA-like domain containing 2 8 98189833-98294393 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA071759 Uncertain Mixed skin: 62.5 -IKBKB IKK-beta, IKK2, IKKB, NFKBIKB ENSG00000104365 Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 8 42271302-42332653 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001249, CAB004447 Approved Approved Cytosol Mixed parathyroid gland: 18.8 -PLAT ENSG00000104368 Plasminogen activator, tissue 8 42175233-42207724 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003412, CAB009335 Supported Approved Actin filaments Tissue enhanced 0 parathyroid gland: 695.5 urinary bladder: 141.1 -JPH1 JP-1 ENSG00000104369 Junctophilin 1 8 74234700-74321328 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008996, HPA009413, CAB013461 Supported Supported Nucleus Tissue enriched 10 skeletal muscle: 88.0 cerebral cortex: 8.6 -DKK4 ENSG00000104371 Dickkopf WNT signaling pathway inhibitor 4 8 42374068-42377232 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052916 Approved Tissue enhanced 0 duodenum: 2.5;esophagus: 5.4;testis: 2.7 urinary bladder: 1.4 -STK3 KRS1, MST2 ENSG00000104375 Serine/threonine kinase 3 8 98401403-98942827 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007120, CAB025316 Uncertain Approved Intermediate filaments
Cytosol
Rods & Rings Expressed in all endometrium: 48.3 -GDAP1 CMT2K, CMT4, CMT4A ENSG00000104381 Ganglioside induced differentiation associated protein 1 8 74321130-74488872 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014266, HPA024334 Supported Supported Mitochondria
Cytosol Tissue enhanced 0 cerebral cortex: 77.0 parathyroid gland: 18.1 -RAB2A RAB2 ENSG00000104388 RAB2A, member RAS oncogene family 8 60516857-60623627 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB018781 Approved Expressed in all cerebral cortex: 108.3 -EIF3E eIF3-p48, eIF3e, EIF3S6, INT6 ENSG00000104408 Eukaryotic translation initiation factor 3, subunit E 8 108201216-108435333 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023973 Approved Validated Nuclear bodies
Cytosol Expressed in all ovary: 729.0 -EMC2 KIAA0103, TTC35 ENSG00000104412 ER membrane protein complex subunit 2 8 108443601-108486918 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022838 Approved Expressed in all testis: 109.5 -ESRP1 FLJ20171, RBM35A ENSG00000104413 Epithelial splicing regulatory protein 1 8 94641074-94707466 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023719, HPA023720, HPA067104 Approved Validated Nucleoplasm
Nuclear bodies Mixed skin: 73.0 -WISP1 CCN4 ENSG00000104415 WNT1 inducible signaling pathway protein 1 8 133191039-133230344 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA007121, CAB012205 Uncertain Validated Cytosol Mixed smooth muscle: 21.8 -NDRG1 CAP43, DRG1, NDR1, RTP, TDD5 ENSG00000104419 N-myc downstream regulated 1 8 133237171-133302022 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006881 Approved Supported Microtubules
Cytosol Expressed in all prostate: 487.4 -ZC2HC1A C8orf70, CGI-62, FAM164A ENSG00000104427 Zinc finger, C2HC-type containing 1A 8 78666047-78719765 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024726 Approved Approved Actin filaments
Cytosol Mixed skin: 52.9 -IL7 IL-7 ENSG00000104432 Interleukin 7 8 78675743-78805523 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA019590 Approved Mixed skin: 10.2 -STMN2 SCG10, SCGN10 ENSG00000104435 Stathmin 2 8 79610814-79666175 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026922 Supported Approved Endoplasmic reticulum
Vesicles Tissue enriched 6 cerebral cortex: 490.7 adrenal gland: 88.6 -ARMC1 Arcp, FLJ10511 ENSG00000104442 Armadillo repeat containing 1 8 65602456-65634217 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026085 Approved Supported Mitochondria Expressed in all cerebral cortex: 34.8 -TRPS1 GC79, LGCR ENSG00000104447 Trichorhinophalangeal syndrome I 8 115408496-115809673 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060380 Supported Nucleoplasm Tissue enhanced 0 breast: 73.5 testis: 22.4 -SPAG1 CILD28, CT140, FLJ32920, HSD-3.8, SP75, TPIS ENSG00000104450 Sperm associated antigen 1 8 100157906-100259278 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023748, HPA053682 Supported Supported Cytosol Tissue enhanced 0 testis: 34.2 rectum: 20.4 -CHRAC1 CHRAC15, YCL1 ENSG00000104472 Chromatin accessibility complex 1 8 140511298-140517137 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059008 Approved Nucleus Expressed in all thyroid gland: 34.9 -NCALD ENSG00000104490 Neurocalcin delta 8 101686543-102124907 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043245 Approved Expressed in all cerebral cortex: 125.4 -SNX16 ENSG00000104497 Sorting nexin 16 8 81799581-81842866 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024730, HPA024731, HPA024817 Approved Supported Vesicles Mixed testis: 27.7 -GML LY6DL ENSG00000104499 Glycosylphosphatidylinositol anchored molecule like 8 142834247-142916506 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 39 adrenal gland: 251.9 testis: 6.4 -UBR5 DD5, EDD, EDD1, HYD, KIAA0896 ENSG00000104517 Ubiquitin protein ligase E3 component n-recognin 5 8 102253012-102412841 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053688 Supported Nucleoplasm
Cytosol Expressed in all testis: 79.7 -GSDMD DF5L, FLJ12150, GSDMDC1 ENSG00000104518 Gasdermin D 8 143553207-143563062 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004656, HPA044487 Uncertain Supported Nucleoplasm Expressed in all spleen: 47.4 -TSTA3 FX, P35B, SDR4E1 ENSG00000104522 Tissue specific transplantation antigen P35B 8 143612618-143618048 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023361 Approved Approved Nucleoplasm
Cytosol Expressed in all stomach: 50.8 -PYCRL FLJ13852 ENSG00000104524 Pyrroline-5-carboxylate reductase-like 8 143603913-143609773 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063416, HPA069706 Uncertain Approved Nucleoplasm
Cytosol Mixed cerebral cortex: 4.1 -EEF1D EF-1D, FLJ20897 ENSG00000104529 Eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 8 143579697-143599541 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045101, HPA051002 Supported Supported Nucleus
Nucleoli fibrillar center Expressed in all ovary: 607.1 -ANXA13 ANX13 ENSG00000104537 Annexin A13 8 123680794-123737407 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018535, HPA019569, HPA019650, CAB025135 Supported Supported Plasma membrane Group enriched 5 duodenum: 304.7;fallopian tube: 91.6;gallbladder: 228.3;small intestine: 240.9 rectum: 39.8 -SQLE ENSG00000104549 Squalene epoxidase 8 124998497-125022283 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018038, HPA020762 Approved Uncertain Vesicles
Cytosol Mixed testis: 107.2 -SH2D4A FLJ20967, PPP1R38, SH2A ENSG00000104611 SH2 domain containing 4A 8 19313617-19396218 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001871, HPA001919 Approved Validated Cytosol Mixed ovary: 44.7 -INTS10 C8orf35, FLJ10569, INT10 ENSG00000104613 Integrator complex subunit 10 8 19817140-19852083 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039129, HPA050570 Uncertain Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 64.7 -ERI1 3'HEXO, THEX1 ENSG00000104626 Exoribonuclease 1 8 9002147-9116746 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033838, HPA055548, HPA056074 Uncertain Approved Vesicles
Microtubules Mixed testis: 16.7 -SLC39A14 KIAA0062, NET34, ZIP14 ENSG00000104635 Solute carrier family 39 (zinc transporter), member 14 8 22367249-22434129 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016508 Approved Approved Endoplasmic reticulum
Golgi apparatus
Plasma membrane Mixed liver: 202.8 -MTMR9 C8orf9, DKFZp434K171, LIP-STYX, MTMR8 ENSG00000104643 Myotubularin related protein 9 8 11284416-11328146 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070944 Approved Actin filaments
Centrosome Mixed cerebral cortex: 22.4 -LEPROTL1 my047, Vps55 ENSG00000104660 Leptin receptor overlapping transcript-like 1 8 30095398-30177208 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047911 Uncertain Expressed in all placenta: 119.4 -DCTN6 WS-3 ENSG00000104671 Dynactin 6 8 30156297-30183640 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024049, HPA024558 Approved Supported Nucleoli
Plasma membrane
Cytosol Expressed in all cerebral cortex: 94.2 -R3HCC1 DKFZp564N123 ENSG00000104679 R3H domain and coiled-coil containing 1 8 23270120-23296279 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023073, HPA023153 Uncertain Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 43.1 -GSR ENSG00000104687 Glutathione reductase 8 30678061-30727926 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001538, CAB008632 Approved Supported Plasma membrane
Cytosol Expressed in all parathyroid gland: 77.8 -TNFRSF10A Apo2, CD261, DR4, TRAILR-1 ENSG00000104689 Tumor necrosis factor receptor superfamily, member 10a 8 23190452-23225126 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050958, HPA054475 Approved Supported Nucleoplasm Mixed lymph node: 16.1 -UBXN8 D8S2298E, REP8, UBXD6 ENSG00000104691 UBX domain protein 8 8 30732247-30767006 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA017725, HPA077538 Approved Supported Nucleoli
Endoplasmic reticulum Expressed in all ovary: 109.4 -PPP2CB PP2Abeta ENSG00000104695 Protein phosphatase 2, catalytic subunit, beta isozyme 8 30774457-30814314 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018600, HPA043236 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 208.0 -ERICH1 ENSG00000104714 Glutamate-rich 1 8 614746-738106 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003725 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all lymph node: 24.6 -NEFM NEF3, NF-M, NFM ENSG00000104722 Neurofilament, medium polypeptide 8 24913012-24919098 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010900, CAB012976, HPA022845, HPA023138 Supported Approved Cytosol Tissue enhanced 0 cerebral cortex: 172.2 seminal vesicle: 40.9 -TUSC3 MGC13453, MRT7, N33, OST3A ENSG00000104723 Tumor suppressor candidate 3 8 15417215-15766649 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049851, HPA049974 Approved Mixed epididymis: 140.7 -ARHGEF10 Gef10, KIAA0294 ENSG00000104728 Rho guanine nucleotide exchange factor (GEF) 10 8 1823976-1958641 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024649 Approved Approved Nucleoplasm Mixed testis: 16.5 -KLHDC4 DKFZp434G0522 ENSG00000104731 Kelch domain containing 4 16 87696485-87765992 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041665 Approved Supported Nucleoli Expressed in all lymph node: 19.3 -MCM4 CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21 ENSG00000104738 Minichromosome maintenance complex component 4 8 47960185-47978160 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004497, HPA004873, HPA031052 Supported Validated Nucleoplasm Expressed in all testis: 78.4 -ADAM2 CT15, FTNB, PH-30b, PH30 ENSG00000104755 ADAM metallopeptidase domain 2 8 39743735-39838289 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB022390, HPA024621, HPA026581 Supported Tissue enriched 288 testis: 41.7 breast: 0.1 -KCTD9 BTBD27, FLJ20038 ENSG00000104756 Potassium channel tetramerization domain containing 9 8 25427847-25458476 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042468, HPA047902 Supported Nucleoplasm
Intermediate filaments
Cytosol Expressed in all prostate: 27.8 -FGL1 HFREP-1 ENSG00000104760 Fibrinogen-like 1 8 17864380-17910365 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 liver: 1003.4 pancreas: 137.7 -ASAH1 AC, ASAH, FLJ21558, PHP32 ENSG00000104763 N-acylsphingosine amidohydrolase (acid ceramidase) 1 8 18056425-18084985 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005468 Supported Expressed in all thyroid gland: 698.9 -BNIP3L BNIP3a, Nix ENSG00000104765 BCL2/adenovirus E1B 19kDa interacting protein 3-like 8 26382898-26505636 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015652, CAB025371 Supported Approved Nuclear speckles
Mitochondria Expressed in all placenta: 150.7 -MAN2B1 LAMAN, MANB ENSG00000104774 Mannosidase, alpha, class 2B, member 1 19 12646511-12666742 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041530, HPA053404 Supported Approved Nucleoplasm
Vesicles Expressed in all spleen: 96.8 -KCNN4 hIKCa1, hKCa4, hSK4, IK, KCa3.1 ENSG00000104783 Potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 19 43766533-43781257 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053841, HPA059622 Approved Tissue enhanced 0 salivary gland: 74.3 stomach: 37.1 -TULP2 CT65, TUBL2 ENSG00000104804 Tubby like protein 2 19 48880965-48898733 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12 testis: 40.9 bone marrow: 3.4 -NUCB1 Calnuc, NUC ENSG00000104805 Nucleobindin 1 19 48900050-48923372 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008176 Supported Supported Golgi apparatus
Microtubules Expressed in all parathyroid gland: 224.3 -DHDH HUM2DD ENSG00000104808 Dihydrodiol dehydrogenase (dimeric) 19 48933682-48944969 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA044131 Approved Approved Nucleoplasm
Actin filaments Tissue enhanced 0 duodenum: 10.5;kidney: 17.8;small intestine: 19.0 prostate: 4.6 -GYS1 GSY, GYS ENSG00000104812 Glycogen synthase 1 (muscle) 19 48968125-48993310 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007793, HPA041598 Supported Approved Microtubules
Cytosol Expressed in all skeletal muscle: 109.8 -MAP4K1 HPK1 ENSG00000104814 Mitogen-activated protein kinase kinase kinase kinase 1 19 38587641-38618882 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007419, CAB007754 Supported Uncertain Nucleoplasm
Plasma membrane Tissue enhanced 0 lymph node: 37.7;spleen: 24.2;tonsil: 28.3 appendix: 19.9 -CGB2 ENSG00000104818 Chorionic gonadotropin, beta polypeptide 2 19 49031912-49033238 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level HPA038925, HPA038934 Supported Approved Cytosol Not detected testis: 0.7 -ECH1 HPXEL ENSG00000104823 Enoyl CoA hydratase 1, peroxisomal 19 38815422-38832005 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002907, HPA005835 Supported Approved Supported Mitochondria Expressed in all skeletal muscle: 188.2 -HNRNPL HNRPL ENSG00000104824 Heterogeneous nuclear ribonucleoprotein L 19 38836388-38852347 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016326, HPA051748, HPA052661 Supported Validated Nucleoplasm Expressed in all bone marrow: 110.6 -NFKBIB IKBB, TRIP9 ENSG00000104825 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 19 38899700-38908893 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010447, HPA063734 Approved Approved Nucleoplasm
Centrosome
Cytosol Tissue enhanced 0 testis: 16.6 appendix: 7.3 -LHB CGB4, hLHB, LSH-B ENSG00000104826 Luteinizing hormone beta polypeptide 19 49015980-49017090 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB022241, CAB022707, HPA038925, HPA038934 Supported Approved Cytosol Tissue enhanced 0 duodenum: 3.3;pancreas: 4.8;testis: 3.1 skin: 0.8 -CGB CGB3 ENSG00000104827 Chorionic gonadotropin, beta polypeptide 19 49022869-49024333 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB000042, CAB010884, HPA038925, HPA038934 Supported Approved Cytosol Tissue enriched 18 placenta: 14.9 testis: 0.8 -TUBB4A beta-5, DYT4, TUBB4 ENSG00000104833 Tubulin, beta 4A class IVa 19 6494319-6502848 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010768, HPA043640, HPA046280 Approved Validated Microtubules Tissue enhanced 0 adrenal gland: 138.8;cerebral cortex: 556.4 testis: 102.6 -SARS2 FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS ENSG00000104835 Seryl-tRNA synthetase 2, mitochondrial 19 38915266-38930896 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052730, HPA056957 Approved Expressed in all thyroid gland: 8.9 -KCNA7 HAK6, Kv1.7 ENSG00000104848 Potassium channel, voltage gated shaker related subfamily A, member 7 19 49067418-49072941 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 37 skeletal muscle: 26.2 esophagus: 0.7 -SNRNP70 RNPU1Z, RPU1, Snp1, SNRP70, U1-70K ENSG00000104852 Small nuclear ribonucleoprotein 70kDa (U1) 19 49085419-49108605 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001718, HPA042050, HPA043516 Supported Validated Nucleoplasm Expressed in all endometrium: 59.8 -CLPTM1 ENSG00000104853 Cleft lip and palate associated transmembrane protein 1 19 44954585-44993341 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA068702 Approved Nuclear membrane
Microtubule organizing center Expressed in all parathyroid gland: 127.5 -RELB REL-B ENSG00000104856 V-rel avian reticuloendotheliosis viral oncogene homolog B 19 45001430-45038198 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007753, HPA040506 Approved Supported Nucleoplasm
Cytosol Expressed in all appendix: 25.8 -CLASRP CLASP, SFRS16, SWAP2 ENSG00000104859 CLK4-associating serine/arginine rich protein 19 45039040-45070956 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060469, HPA062455 Approved Validated Nucleus Expressed in all bone marrow: 11.9 -LIN7B LIN-7B, MALS-2, VELI2 ENSG00000104863 Lin-7 homolog B (C. elegans) 19 49114324-49118460 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 18.2 -PPP1R37 LRRC68 ENSG00000104866 Protein phosphatase 1, regulatory subunit 37 19 45091396-45148077 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041500 Approved Approved Cytosol Expressed in all cerebral cortex: 22.4 -FCGRT alpha-chain, FCRN ENSG00000104870 Fc fragment of IgG, receptor, transporter, alpha 19 49506816-49526333 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012122, HPA015130 Approved Expressed in all small intestine: 318.5 -PIH1D1 FLJ20643, NOP17 ENSG00000104872 PIH1 domain containing 1 19 49446298-49453497 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047258 Approved Approved Cytosol Expressed in all fallopian tube: 64.2 -CKM CKMM ENSG00000104879 Creatine kinase, muscle 19 45306414-45322977 Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047859 Supported Tissue enriched 15 skeletal muscle: 23804.3 heart muscle: 1618.7 -ARHGEF18 KIAA0521, MGC15913, P114-RhoGEF ENSG00000104880 Rho/Rac guanine nucleotide exchange factor (GEF) 18 19 7395113-7472477 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042689, HPA071867 Approved Validated Cytosol Expressed in all spleen: 31.1 -PPP1R13L IASPP, RAI ENSG00000104881 Protein phosphatase 1, regulatory subunit 13 like 19 45379634-45406349 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005016, HPA041231, HPA059883 Approved Validated Cytosol Tissue enhanced 0 skin: 191.2 esophagus: 54.1 -PEX11G ENSG00000104883 Peroxisomal biogenesis factor 11 gamma 19 7476875-7497449 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069817 Uncertain Mixed testis: 15.6 -ERCC2 EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD ENSG00000104884 Excision repair cross-complementation group 2 19 45349837-45370918 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005375, HPA038057, HPA069266 Approved Supported Nucleoplasm Expressed in all testis: 16.2 -DOT1L DOT1, KIAA1814, KMT4 ENSG00000104885 DOT1-like histone H3K79 methyltransferase 19 2164149-2232578 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011875, HPA071217 Validated Nucleoplasm Tissue enriched 6 testis: 92.5 appendix: 14.5 -PLEKHJ1 FLJ10297 ENSG00000104886 Pleckstrin homology domain containing, family J member 1 19 2230084-2237704 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA048989 Approved Approved Mitochondria Expressed in all duodenum: 110.9 -SLC17A7 BNPI, VGLUT1 ENSG00000104888 Solute carrier family 17 (vesicular glutamate transporter), member 7 19 49429401-49442360 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB037183, HPA050458, HPA063679 Supported Tissue enriched 178 cerebral cortex: 586.2 adipose tissue: 3.2 -RNASEH2A AGS4, RNASEHI, RNHIA, RNHL ENSG00000104889 Ribonuclease H2, subunit A 19 12806580-12813638 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042692 Validated Nucleus
Cytosol Expressed in all testis: 21.6 -KLC3 KLC2L, KLCt, KNS2B ENSG00000104892 Kinesin light chain 3 19 45333434-45351520 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052797, HPA056508 Approved Approved Nucleoplasm
Actin filaments
Cytosol Tissue enriched 6 skin: 64.0 esophagus: 10.0 -CD37 TSPAN26 ENSG00000104894 CD37 molecule 19 49335171-49343335 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002492, HPA032120, HPA032121 Supported Tissue enhanced 0 lymph node: 244.2;spleen: 212.9 appendix: 133.5 -SF3A2 Prp11, PRPF11, SAP62, SF3a66 ENSG00000104897 Splicing factor 3a, subunit 2, 66kDa 19 2236504-2248679 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042843, HPA049439 Supported Approved Nucleoplasm Expressed in all testis: 50.5 -AMH MIS ENSG00000104899 Anti-Mullerian hormone 19 2249309-2252073 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 testis: 1.7 cerebral cortex: 0.2 -DKKL1 CT34, SGY-1 ENSG00000104901 Dickkopf-like 1 19 49361783-49375116 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB025410, HPA047194 Supported Approved Vesicles Tissue enriched 137 testis: 265.5 fallopian tube: 1.9 -LYL1 bHLHa18 ENSG00000104903 Lymphoblastic leukemia associated hematopoiesis regulator 1 19 13099033-13103161 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA075004 Approved Golgi apparatus Tissue enhanced 0 bone marrow: 22.9;spleen: 21.2 appendix: 14.8 -OAZ1 AZI, MGC138338, OAZ ENSG00000104904 Ornithine decarboxylase antizyme 1 19 2269509-2273490 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA009291 Uncertain Approved Vesicles
Microtubule organizing center Expressed in all lymph node: 271.9 -TRMT1 FLJ20244, TRM1 ENSG00000104907 TRNA methyltransferase 1 19 13104902-13117567 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041130, HPA041380 Approved Approved Nucleus
Plasma membrane
Cytosol Expressed in all lymph node: 27.0 -STX10 hsyn10, SYN10 ENSG00000104915 Syntaxin 10 19 13144058-13150383 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035303, HPA056439 Approved Approved Golgi apparatus Expressed in all skin: 57.0 -RETN ADSF, FIZZ3, RETN1 ENSG00000104918 Resistin 19 7669044-7670454 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 bone marrow: 159.8 lung: 26.1 -FCER2 CD23, CD23A, CLEC4J, FCE2 ENSG00000104921 Fc fragment of IgE, low affinity II, receptor for (CD23) 19 7688758-7702146 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002624, HPA008928 Approved Group enriched 7 appendix: 22.9;lymph node: 48.1;spleen: 53.7;tonsil: 39.4 adipose tissue: 5.7 -DMPK DM, DM1, DM1PK, DMK, MDPK, MT-PK ENSG00000104936 Dystrophia myotonica-protein kinase 19 45769717-45782552 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007164, HPA008905 Supported Approved Vesicles
Cytosol Expressed in all smooth muscle: 96.5 -CLEC4M CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, LSIGN ENSG00000104938 C-type lectin domain family 4, member M 19 7763149-7769605 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033689, CAB033691, HPA042661 Supported Group enriched 7 liver: 34.7;lymph node: 20.6;placenta: 12.4 testis: 3.3 -RSPH6A RSHL1, RSP4, RSP6, RSPH4B ENSG00000104941 Radial spoke head 6 homolog A (Chlamydomonas) 19 45795710-45815319 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045382 Approved Tissue enriched 7 testis: 30.5 thyroid gland: 4.5 -TBC1D17 FLJ12168 ENSG00000104946 TBC1 domain family, member 17 19 49877425-49888749 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA068119 Uncertain Expressed in all cerebral cortex: 29.9 -IL4I1 FIG1 ENSG00000104951 Interleukin 4 induced 1 19 49889654-49929539 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045598 Supported Tissue enhanced 0 appendix: 25.3;testis: 31.9 lymph node: 10.6 -TLE6 FLJ14009, GRG6 ENSG00000104953 Transducin-like enhancer of split 6 19 2977446-2995184 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 thyroid gland: 9.7 placenta: 6.5 -CCDC130 MGC10471 ENSG00000104957 Coiled-coil domain containing 130 19 13731760-13763296 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056977 Approved Approved Vesicles Expressed in all spleen: 25.3 -PTOV1 ENSG00000104960 Prostate tumor overexpressed 1 19 49850735-49860744 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051812 Supported Nucleus Expressed in all adrenal gland: 62.2 -AES GRG5, TLE5 ENSG00000104964 Amino-terminal enhancer of split 19 3052910-3063107 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049499 Approved Nucleoplasm Expressed in all cerebral cortex: 332.3 -NOVA2 ANOVA, NOVA3 ENSG00000104967 Neuro-oncological ventral antigen 2 19 45933734-45973546 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045607 Supported Approved Nucleoplasm
Nuclear bodies
Golgi apparatus Tissue enhanced 0 cerebral cortex: 24.4 placenta: 5.9 -SGTA SGT ENSG00000104969 Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 19 2754714-2783371 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056309 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 64.8 -KIR3DX1 FLJ00060, LENG12 ENSG00000104970 Killer cell immunoglobulin-like receptor, three domains, X1 19 54532692-54545771 Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA052110 Uncertain Not detected bone marrow: 0.3 -LILRB1 CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7 ENSG00000104972 Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 19 54617158-54637528 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 appendix: 9.1;lymph node: 6.3;spleen: 10.1 smooth muscle: 3.7 -MED25 ACID1, ARC92, DKFZp434K0512, TCBAP0758 ENSG00000104973 Mediator complex subunit 25 19 49818279-49838816 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068802 Supported Nucleoplasm Expressed in all testis: 111.3 -LILRA1 CD85i, LIR-6, LIR6 ENSG00000104974 Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 19 54573879-54602090 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level Not detected spleen: 0.9 -SNAPC2 PTFdelta, SNAP45 ENSG00000104976 Small nuclear RNA activating complex, polypeptide 2, 45kDa 19 7920316-7923250 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049843 Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all endometrium: 30.8 -C19orf53 HSPC023, LYDG10 ENSG00000104979 Chromosome 19 open reading frame 53 19 13774168-13778462 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059928, HPA061291 Approved Supported Nucleus
Nucleoli Expressed in all fallopian tube: 115.6 -TIMM44 TIM44 ENSG00000104980 Translocase of inner mitochondrial membrane 44 homolog (yeast) 19 7926718-7943920 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043052 Supported Validated Mitochondria Expressed in all heart muscle: 18.5 -CCDC61 ENSG00000104983 Coiled-coil domain containing 61 19 45995461-46021318 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040325, HPA061548 Uncertain Approved Nucleus Expressed in all testis: 31.1 -IL27RA CRL1, IL-27R, TCCR, WSX-1, WSX1, zcytor1 ENSG00000104998 Interleukin 27 receptor, alpha 19 14031748-14053216 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047188 Approved Vesicles
Cytosol Mixed tonsil: 31.5 -ASF1B FLJ10604 ENSG00000105011 Anti-silencing function 1B histone chaperone 19 14119509-14136956 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054036 Supported Nucleoplasm Tissue enhanced 0 testis: 37.1 lymph node: 24.3 -TNNT1 ANM, FLJ98147, MGC104241, NEM5, STNT, TNT, TNTS ENSG00000105048 Troponin T type 1 (skeletal, slow) 19 55132794-55149354 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015168, HPA058448 Supported Approved Nucleus
Golgi apparatus
Cytosol Tissue enriched 12 skeletal muscle: 7570.4 esophagus: 636.8 -VRK3 ENSG00000105053 Vaccinia related kinase 3 19 49976467-50025946 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056489 Approved Supported Nucleus
Vesicles Expressed in all testis: 168.2 -FAM32A DKFZP586O0120 ENSG00000105058 Family with sequence similarity 32, member A 19 16185380-16192046 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051712 Approved Supported Nucleus
Nucleoli Expressed in all placenta: 88.9 -PPP6R1 KIAA1115, SAP190, SAPS1 ENSG00000105063 Protein phosphatase 6, regulatory subunit 1 19 55229780-55258995 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043989, HPA063681 Approved Validated Cytosol Expressed in all testis: 117.3 -C19orf44 FLJ21742 ENSG00000105072 Chromosome 19 open reading frame 44 19 16496311-16521352 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041683, HPA049414 Uncertain Approved Nucleus
Nuclear bodies Tissue enhanced 0 testis: 20.6 parathyroid gland: 11.6 -MED26 CRSP7, CRSP70 ENSG00000105085 Mediator complex subunit 26 19 16574907-16629062 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071835 Approved Nucleoplasm
Vesicles
Cytosol Tissue enriched 6 testis: 42.0 bone marrow: 6.8 -OLFM2 NOE2, OlfC ENSG00000105088 Olfactomedin 2 19 9853718-9936552 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049961, HPA057771 Uncertain Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 124.3;skin: 111.4 adipose tissue: 36.8 -RASAL3 FLJ21438 ENSG00000105122 RAS protein activator like 3 19 15451624-15464571 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043417 Approved Tissue enhanced 0 lymph node: 38.0 spleen: 25.0 -AKAP8 AKAP95, DKFZp586B1222 ENSG00000105127 A kinase (PRKA) anchor protein 8 19 15353385-15379798 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004776 Supported Supported Nucleoplasm Expressed in all bone marrow: 13.1 -EPHX3 ABHD9, FLJ22408 ENSG00000105131 Epoxide hydrolase 3 19 15226919-15233435 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA012842 Uncertain Group enriched 7 esophagus: 35.3;skin: 62.9;tonsil: 25.2 urinary bladder: 5.5 -ILVBL 209L8, AHAS, FLJ39061, ILV2H, MGC1269, MGC19535 ENSG00000105135 IlvB (bacterial acetolactate synthase)-like 19 15114984-15125785 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067682 Approved Approved Golgi apparatus
Vesicles Expressed in all thyroid gland: 80.0 -ZNF419 ZAPHIR, ZNF419A ENSG00000105136 Zinc finger protein 419 19 57487711-57496097 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA003152, HPA003274 Uncertain Supported Nucleus
Nucleoli fibrillar center Mixed parathyroid gland: 15.7 -SYDE1 7h3, FLJ13511 ENSG00000105137 Synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 19 15107403-15114988 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013328 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Mixed placenta: 21.7 -CASP14 MGC119078, MGC119079, MICE ENSG00000105141 Caspase 14, apoptosis-related cysteine peptidase 19 15049384-15058293 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010059, HPA027062 Supported Supported Cytosol Tissue enriched 56 skin: 560.0 breast: 10.0 -SLC1A6 EAAT4 ENSG00000105143 Solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 19 14950034-15022990 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041505, HPA044066 Supported Uncertain Intermediate filaments Group enriched 6 cerebral cortex: 16.2;skin: 8.9;testis: 36.8 epididymis: 3.7 -AURKC ARK3, AurC, STK13 ENSG00000105146 Aurora kinase C 19 57230802-57235548 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA034859 Uncertain Tissue enriched 10 testis: 73.4 spleen: 7.0 -POP4 RPP29 ENSG00000105171 POP4 homolog, ribonuclease P/MRP subunit 19 29604017-29617237 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042748 Approved Expressed in all testis: 15.3 -CCNE1 CCNE ENSG00000105173 Cyclin E1 19 29811898-29824308 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000308, CAB016682, HPA018169 Approved Validated Nucleoplasm Tissue enhanced 0 placenta: 44.3 testis: 22.4 -URI1 C19orf2, FLJ10575, NNX3, PPP1R19, RMP, URI ENSG00000105176 URI1, prefoldin-like chaperone 19 29923644-30016608 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071709 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 94.6 -PDCD5 MGC9294, TFAR19 ENSG00000105185 Programmed cell death 5 19 32581068-32587452 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018471 Supported Approved Nucleus
Cytosol Expressed in all testis: 174.5 -ANKRD27 DKFZp434L0718, FLJ00040, VARP ENSG00000105186 Ankyrin repeat domain 27 (VPS9 domain) 19 32597007-32676597 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042769 Approved Validated Cytosol Expressed in all testis: 32.4 -RPS16 S16 ENSG00000105193 Ribosomal protein S16 19 39433207-39435948 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064222 Approved Validated Endoplasmic reticulum
Cytosol Expressed in all ovary: 3699.3 -TIMM50 TIM50L ENSG00000105197 Translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 19 39480412-39493785 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048843, HPA056448 Supported Supported Nucleoplasm
Mitochondria Expressed in all testis: 80.4 -LGALS13 PLAC8, PP13 ENSG00000105198 Lectin, galactoside-binding, soluble, 13 19 39602501-39607476 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 35 placenta: 16.5 testis: 0.4 -FBL FIB, FLRN, RNU3IP1 ENSG00000105202 Fibrillarin 19 39834458-39846414 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001514, HPA049546 Supported Validated Nucleoli fibrillar center Expressed in all ovary: 213.7 -DYRK1B MIRK ENSG00000105204 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 19 39825350-39834201 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028522, HPA028786 Uncertain Approved Nucleus Tissue enhanced 0 skeletal muscle: 37.4 testis: 33.7 -CLC Gal-10, LGALS10, MGC149659 ENSG00000105205 Charcot-Leyden crystal galectin 19 39731250-39738028 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041751 Supported Tissue enhanced 0 bone marrow: 286.6 urinary bladder: 57.6 -CNTD2 CCNP, FLJ13265 ENSG00000105219 Cyclin N-terminal domain containing 2 19 40222208-40226690 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045615 Uncertain Not detected adipose tissue: 0.9 -GPI AMF, NLK ENSG00000105220 Glucose-6-phosphate isomerase 19 34359480-34402156 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018655, HPA024305, CAB040563, HPA052171 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 308.2 -AKT2 ENSG00000105221 V-akt murine thymoma viral oncogene homolog 2 19 40230317-40285536 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004204, HPA064521 Uncertain Supported Nucleus
Vesicles
Cytosol Expressed in all thyroid gland: 169.5 -PLD3 HU-K4 ENSG00000105223 Phospholipase D family, member 3 19 40348456-40380439 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012800, CAB020812 Approved Expressed in all cerebral cortex: 496.2 -PRX KIAA1620 ENSG00000105227 Periaxin 19 40393768-40413366 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001868 Supported Approved Golgi apparatus
Vesicles
Plasma membrane Tissue enhanced 0 lung: 28.9 parathyroid gland: 9.3 -PIAS4 FLJ12419, Piasg, PIASY, ZMIZ6 ENSG00000105229 Protein inhibitor of activated STAT, 4 19 4007646-4039386 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010598 Approved Approved Nucleoplasm Expressed in all testis: 29.3 -NUMBL CAG3A, CTG3a, NUMB-R, NUMBLIKE, NUMBR, TNRC23 ENSG00000105245 Numb homolog (Drosophila)-like 19 40665905-40690972 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058251, HPA058380 Approved Expressed in all cerebral cortex: 41.8 -EBI3 ENSG00000105246 Epstein-Barr virus induced 3 19 4229498-4237531 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046635 Supported Tissue enriched 8 placenta: 208.2 spleen: 26.5 -CCDC94 FLJ10374 ENSG00000105248 Coiled-coil domain containing 94 19 4247079-4269090 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043606, HPA055675 Approved Supported Nucleoplasm Expressed in all bone marrow: 28.0 -SHD ENSG00000105251 Src homology 2 domain containing transforming protein D 19 4278601-4290724 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA017955 Approved Uncertain Microtubule organizing center
Cytosol Group enriched 15 cerebral cortex: 22.2;heart muscle: 4.5 appendix: 0.9 -TBCB CG22, CKAP1, CKAPI ENSG00000105254 Tubulin folding cofactor B 19 36114289-36125947 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041428, HPA041722 Approved Supported Cytosol Expressed in all cerebral cortex: 250.6 -FSD1 MGC3213, MIR1 ENSG00000105255 Fibronectin type III and SPRY domain containing 1 19 4304600-4323843 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043141 Supported Group enriched 12 cerebral cortex: 25.5;testis: 9.1 lymph node: 1.4 -POLR2I hRPB14.5, RPB9 ENSG00000105258 Polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 19 36113710-36115346 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035632, HPA045156 Uncertain Validated Nucleoplasm Expressed in all cerebral cortex: 18.5 -OVOL3 HOVO3 ENSG00000105261 Ovo-like zinc finger 3 19 36111151-36113711 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 skin: 1.0;testis: 2.9 appendix: 0.4 -CLIP3 CLIPR-59, RSNL1 ENSG00000105270 CAP-GLY domain containing linker protein 3 19 36014660-36033343 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 248.3 smooth muscle: 55.5 -ZFR2 KIAA1086 ENSG00000105278 Zinc finger RNA binding protein 2 19 3804024-3869032 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043275, HPA055678 Uncertain Uncertain Nucleoplasm Group enriched 9 adrenal gland: 3.8;cerebral cortex: 12.7;testis: 19.0 fallopian tube: 1.3 -SLC1A5 AAAT, ASCT2, M7V1, RDRC ENSG00000105281 Solute carrier family 1 (neutral amino acid transporter), member 5 19 46774883-46788594 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035239, HPA035240 Supported Validated Plasma membrane Expressed in all epididymis: 117.4 -PRKD2 DKFZP586E0820, HSPC187, PKD2 ENSG00000105287 Protein kinase D2 19 46674275-46717127 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021490, HPA056727 Supported Supported Nucleoplasm
Cytosol Expressed in all spleen: 61.4 -TJP3 ZO-3 ENSG00000105289 Tight junction protein 3 19 3708109-3750813 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013244, HPA046863, HPA053337 Supported Validated Nucleoplasm
Cell Junctions Tissue enhanced 0 duodenum: 42.7;small intestine: 42.1 colon: 31.1 -APLP1 APLP ENSG00000105290 Amyloid beta (A4) precursor-like protein 1 19 35867899-35879791 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028970, HPA028971 Supported Tissue enriched 13 cerebral cortex: 441.8 adrenal gland: 34.6 -CACTIN C19orf29, cactin, fSAPc, NY-REN-24 ENSG00000105298 Cactin, spliceosome C complex subunit 19 3610641-3626815 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042504, HPA042548 Approved Supported Nucleoplasm
Nuclear speckles
Cytosol Expressed in all spleen: 14.7 -CCDC9 DKFZP586M1019 ENSG00000105321 Coiled-coil domain containing 9 19 47255980-47271953 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045624, HPA072007 Approved Approved Cytosol Expressed in all testis: 30.3 -HNRNPUL1 E1B-AP5, E1BAP5, FLJ12944, HNRPUL1 ENSG00000105323 Heterogeneous nuclear ribonucleoprotein U-like 1 19 41262496-41307598 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046290, CAB046477, HPA049475 Supported Validated Nucleoplasm Expressed in all testis: 150.0 -FZR1 CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1, KIAA1242 ENSG00000105325 Fizzy/cell division cycle 20 related 1 19 3506273-3538330 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043536 Approved Supported Nucleoplasm
Nuclear membrane Expressed in all testis: 33.1 -BBC3 JFY1, PUMA ENSG00000105327 BCL2 binding component 3 19 47220822-47232766 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007752, HPA070403 Approved Approved Cytosol Mixed skin: 4.7 -TGFB1 CED, DPD1, TGFB, TGFbeta ENSG00000105329 Transforming growth factor, beta 1 19 41301587-41353911 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000361, CAB073543 Approved Uncertain Cytosol Expressed in all spleen: 86.1 -DENND3 KIAA0870 ENSG00000105339 DENN/MADD domain containing 3 8 141117278-141195808 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024491 Approved Vesicles
Cytosol Mixed bone marrow: 68.7 -ATP5SL FLJ10241 ENSG00000105341 ATP5S-like 19 41431318-41440717 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041427 Approved Approved Mitochondria Expressed in all heart muscle: 51.3 -CEACAM4 CGM7 ENSG00000105352 Carcinoembryonic antigen-related cell adhesion molecule 4 19 41618971-41627074 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 appendix: 6.8;bone marrow: 14.0;spleen: 9.1 adipose tissue: 1.7 -PLIN3 M6PRBP1, PP17, TIP47 ENSG00000105355 Perilipin 3 19 4838341-4867768 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006427, HPA066538 Uncertain Validated Lipid droplets
Cytosol Expressed in all esophagus: 116.2 -MYH14 DFNA4, FLJ13881, KIAA2034, MHC16, MYH17 ENSG00000105357 Myosin, heavy chain 14, non-muscle 19 50188186-50310545 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062391, HPA067889, HPA070260 Approved Approved Nucleoplasm Mixed small intestine: 85.2 -MRPL4 CGI-28 ENSG00000105364 Mitochondrial ribosomal protein L4 19 10251901-10260045 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051261 Approved Expressed in all cerebral cortex: 39.0 -SIGLEC8 MGC59785, SAF2, SIGLEC-8, SIGLEC8L ENSG00000105366 Sialic acid binding Ig-like lectin 8 19 51450847-51458456 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA012556 Approved Uncertain Cytosol Mixed spleen: 7.6 -CD79A IGA, MB-1 ENSG00000105369 CD79a molecule, immunoglobulin-associated alpha 19 41877120-41881372 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000019 Supported Group enriched 6 appendix: 275.4;lymph node: 522.9;spleen: 324.4;tonsil: 440.3 stomach: 62.7 -LIM2 MP17, MP19 ENSG00000105370 Lens intrinsic membrane protein 2, 19kDa 19 51379909-51387960 Disease related genes, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.4 -ICAM4 CD242, LW ENSG00000105371 Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 19 10286967-10288522 Blood group antigen proteins, CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA067629 Approved Nuclear speckles Tissue enhanced 0 epididymis: 10.3;lung: 14.6 bone marrow: 8.8 -RPS19 DBA, S19 ENSG00000105372 Ribosomal protein S19 19 41859918-41872926 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 3245.6 -GLTSCR2 PICT-1 ENSG00000105373 Glioma tumor suppressor candidate region gene 2 19 47745522-47757058 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018999, HPA049600 Approved Validated Nucleoli Expressed in all ovary: 531.9 -NKG7 GIG1, GMP-17 ENSG00000105374 Natural killer cell granule protein 7 19 51371606-51372715 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA071454 Approved Vesicles Tissue enhanced 0 bone marrow: 352.2;spleen: 153.8 lymph node: 124.8 -ICAM5 TLCN, TLN ENSG00000105376 Intercellular adhesion molecule 5, telencephalin 19 10289981-10296778 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008943, HPA009083, CAB025178 Supported Approved Nucleoplasm Tissue enriched 10 cerebral cortex: 21.6 lung: 2.0 -ETFB ENSG00000105379 Electron-transfer-flavoprotein, beta polypeptide 19 51345169-51366418 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018910, HPA018921, HPA018923 Supported Validated Mitochondria Expressed in all liver: 171.8 -CD33 FLJ00391, p67, SIGLEC-3, SIGLEC3 ENSG00000105383 CD33 molecule 19 51225064-51243860 CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011442, HPA035832, HPA064807 Approved Supported Nucleus
Plasma membrane Tissue enhanced 0 spleen: 33.6 bone marrow: 20.9 -CEACAM5 CD66e, CEA ENSG00000105388 Carcinoembryonic antigen-related cell adhesion molecule 5 19 41708585-41729798 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000021, CAB000022, HPA011041, HPA019758 Supported Supported Plasma membrane Tissue enhanced 0 colon: 1030.9;rectum: 1100.3 appendix: 268.1 -CRX CORD2, CRD, LCA7, OTX3 ENSG00000105392 Cone-rod homeobox 19 47819779-47843330 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036762, HPA036763 Supported Not detected epididymis: 0.3 -BABAM1 C19orf62, FLJ20571, HSPC142, MERIT40, NBA1 ENSG00000105393 BRISC and BRCA1 A complex member 1 19 17267350-17281249 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054386, HPA068786 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all cerebral cortex: 84.4 -TYK2 JTK1 ENSG00000105397 Tyrosine kinase 2 19 10350529-10380676 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005157 Uncertain Approved Cytosol Expressed in all spleen: 101.6 -SULT2A1 DHEA-ST, STD ENSG00000105398 Sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 19 47870466-47886397 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018755, HPA041487, HPA063633 Supported Supported Cytosol Tissue enhanced 0 adrenal gland: 190.8;liver: 513.8 small intestine: 93.1 -CDC37 P50CDC37 ENSG00000105401 Cell division cycle 37 19 10391134-10420121 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003928, CAB004214 Supported Validated Cytosol Expressed in all appendix: 114.0 -NAPA ENSG00000105402 N-ethylmaleimide-sensitive factor attachment protein, alpha 19 47487637-47515240 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010100, HPA046149, HPA050196 Approved Uncertain Cytosol Expressed in all prostate: 146.3 -RABAC1 PRA1, PRAF1, YIP3 ENSG00000105404 Rab acceptor 1 (prenylated) 19 41956681-41959390 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019320, HPA029171 Supported Approved Nuclear membrane
Nucleoli fibrillar center Expressed in all cerebral cortex: 107.6 -ATP1A3 DYT12 ENSG00000105409 ATPase, Na+/K+ transporting, alpha 3 polypeptide 19 41966582-41997497 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033630, HPA045367, HPA056446 Supported Tissue enhanced 0 cerebral cortex: 376.4;heart muscle: 94.2 testis: 54.1 -MEIS3 DKFZp547H236, MRG2 ENSG00000105419 Meis homeobox 3 19 47403124-47419523 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA046699 Uncertain Approved Nucleoplasm Tissue enhanced 0 endometrium: 82.2 cerebral cortex: 65.0 -PTPRS ENSG00000105426 Protein tyrosine phosphatase, receptor type, S 19 5158495-5340803 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054747 Approved Plasma membrane
Cytosol Expressed in all cerebral cortex: 70.8 -CNFN PLAC8L2 ENSG00000105427 Cornifelin 19 42387019-42390287 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049073, HPA053997 Supported Approved Microtubules
Cytokinetic bridge Group enriched 33 esophagus: 1163.5;skin: 272.0;tonsil: 270.8 breast: 17.4 -ZNRF4 RNF204, spzn, Ssrzf1 ENSG00000105428 Zinc and ring finger 4 19 5455431-5456856 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 495 testis: 49.4 epididymis: 0.0 -MEGF8 C19orf49, EGFL4, FLJ22365, SBP1 ENSG00000105429 Multiple EGF-like-domains 8 19 42325609-42378769 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049248 Approved Expressed in all cerebral cortex: 38.1 -KDELR1 ERD2, ERD2.1, HDEL ENSG00000105438 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 19 48382570-48391553 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017455 Approved Supported Golgi apparatus
Vesicles Expressed in all parathyroid gland: 259.3 -CYTH2 ARNO, CTS18.1, cytohesin-2, PSCD2, PSCD2L, Sec7p-L, Sec7p-like ENSG00000105443 Cytohesin 2 19 48469032-48482314 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB014872 Uncertain Supported Golgi apparatus
Plasma membrane
Cytosol Mixed testis: 31.4 -GRWD1 GRWD, RRB1, WDR28 ENSG00000105447 Glutamate-rich WD repeat containing 1 19 48445773-48457022 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042643, HPA055680 Approved Supported Nucleus
Nucleoli Expressed in all parathyroid gland: 19.8 -GRIN2D EB11, GluN2D, NMDAR2D, NR2D ENSG00000105464 Glutamate receptor, ionotropic, N-methyl D-aspartate 2D 19 48394875-48444931 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 2.3 placenta: 1.3 -SYNGR4 ENSG00000105467 Synaptogyrin 4 19 48364395-48376376 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030075, HPA059286 Approved Approved Golgi apparatus Tissue enriched 11 testis: 46.8 parathyroid gland: 4.4 -CLEC11A CLECSF3, LSLCL, P47, SCGF ENSG00000105472 C-type lectin domain family 11, member A 19 50723329-50725718 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042690 Approved Approved Centrosome Tissue enhanced 0 bone marrow: 81.6 cervix: 18.9 -CCDC114 CILD20, FLJ32926 ENSG00000105479 Coiled-coil domain containing 114 19 48296457-48321894 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042524 Approved Group enriched 5 fallopian tube: 6.5;testis: 5.8 lung: 1.1 -CARD8 CARDINAL, Dakar, KIAA0955, NDPP, TUCAN ENSG00000105483 Caspase recruitment domain family, member 8 19 48180770-48255946 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042071, HPA043513 Supported Validated Nucleoplasm
Cytosol Expressed in all spleen: 50.8 -LIG1 ENSG00000105486 Ligase I, DNA, ATP-dependent 19 48115445-48170603 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037015, HPA041431, HPA048071 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Mixed bone marrow: 21.0 -SIGLEC6 CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6 ENSG00000105492 Sialic acid binding Ig-like lectin 6 19 51519525-51531856 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009084, HPA018198 Supported Tissue enriched 24 placenta: 147.1 lung: 6.0 -ZNF175 OTK18 ENSG00000105497 Zinc finger protein 175 19 51571298-51592508 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA002717 Uncertain Supported Nucleoplasm
Intermediate filaments
Cytosol Mixed parathyroid gland: 21.2 -PLA2G4C cPLA2-gamma ENSG00000105499 Phospholipase A2, group IVC (cytosolic, calcium-independent) 19 48047843-48110817 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043083 Approved Approved Cytosol Mixed parathyroid gland: 28.9 -SIGLEC5 CD170, CD33L2, OB-BP2, SIGLEC-5 ENSG00000105501 Sialic acid binding Ig-like lectin 5 19 51611503-51645545 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009085, CAB024900 Supported Tissue enhanced 0 appendix: 13.5;bone marrow: 13.3;spleen: 11.6 lymph node: 4.2 -CABP5 CABP3 ENSG00000105507 Calcium binding protein 5 19 48029953-48044053 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 30 epididymis: 5.3 spleen: 0.1 -HAS1 HAS ENSG00000105509 Hyaluronan synthase 1 19 51713112-51723994 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA067602 Approved Approved Nucleoplasm
Plasma membrane Tissue enhanced 0 adipose tissue: 26.9 appendix: 9.1 -RAB3D D2-2, GOV, RAB16, RAD3D ENSG00000105514 RAB3D, member RAS oncogene family 19 11322046-11346270 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018067, HPA063283 Approved Approved Vesicles Tissue enhanced 0 skin: 62.7 esophagus: 28.2 -DBP DABP ENSG00000105516 D site of albumin promoter (albumin D-box) binding protein 19 48630030-48637438 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all thyroid gland: 41.3 -TMEM205 MBC3205, UNQ501 ENSG00000105518 Transmembrane protein 205 19 11342776-11346518 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041504 Approved Approved Nucleoplasm
Nuclear membrane
Endoplasmic reticulum Expressed in all parathyroid gland: 253.1 -CAPS CAPS1, MGC126562 ENSG00000105519 Calcyphosine 19 5911707-5916208 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043520 Supported Supported Nucleus
Plasma membrane
Cytosol Tissue enriched 10 fallopian tube: 493.6 cervix: 51.4 -PLPPR2 LPPR2, PRG-4 ENSG00000105520 Phospholipid phosphatase related 2 19 11355386-11365698 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048973 Uncertain Approved Nucleoplasm Expressed in all cerebral cortex: 77.4 -FAM83E FLJ20200 ENSG00000105523 Family with sequence similarity 83, member E 19 48600810-48614854 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049305 Uncertain Tissue enhanced 0 duodenum: 31.7;small intestine: 36.0;stomach: 41.5 colon: 23.0 -RASIP1 FLJ20401, RAIN ENSG00000105538 Ras interacting protein 1 19 48720587-48740721 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed spleen: 18.8 -THEG CT56, THEG1 ENSG00000105549 Theg spermatid protein 19 361747-376670 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 9 testis: 33.5 skin: 3.9 -FGF21 ENSG00000105550 Fibroblast growth factor 21 19 48755559-48758330 Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA061286 Supported Tissue enriched 38 liver: 6.6 thyroid gland: 0.1 -BCAT2 BCAM, BCT2 ENSG00000105552 Branched chain amino-acid transaminase 2, mitochondrial 19 48795062-48811029 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054091 Supported Expressed in all adrenal gland: 54.3 -MIER2 KIAA1193 ENSG00000105556 Mesoderm induction early response 1, family member 2 19 301444-344807 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041439 Uncertain Approved Nucleoplasm
Cytosol Mixed testis: 12.8 -PLEKHA4 PEPP1 ENSG00000105559 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 19 48837097-48868632 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042978, HPA048473 Uncertain Approved Plasma membrane
Cytokinetic bridge
Centrosome
Cytosol Mixed ovary: 22.5 -PPP2R1A PP2A-Aalpha, PR65A ENSG00000105568 Protein phosphatase 2, regulatory subunit A, alpha 19 52190039-52229533 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018599 Approved Cytosol Expressed in all fallopian tube: 205.2 -TNPO2 FLJ12155, IPO3, KPNB2B, TRN2 ENSG00000105576 Transportin 2 19 12699194-12724011 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB046446, HPA071498 Approved Approved Nucleus
Nucleoli Expressed in all cerebral cortex: 91.2 -WDR83OS C19orf56, PTD008 ENSG00000105583 WD repeat domain 83 opposite strand 19 12668071-12671356 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA065685 Approved Endoplasmic reticulum Expressed in all fallopian tube: 315.6 -CACNG7 ENSG00000105605 Calcium channel, voltage-dependent, gamma subunit 7 19 53909335-53943941 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 101 cerebral cortex: 63.9 adrenal gland: 0.6 -GCDH ACAD5 ENSG00000105607 Glutaryl-CoA dehydrogenase 19 12891026-12914207 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043252, HPA048492 Supported Supported Mitochondria Expressed in all liver: 42.8 -LILRB5 CD85c, LIR-8, LIR8 ENSG00000105609 Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 19 54249431-54257301 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012069 Approved Tissue enhanced 0 spleen: 26.5 adipose tissue: 11.4 -KLF1 EKLF ENSG00000105610 Kruppel-like factor 1 (erythroid) 19 12884423-12887181 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051850 Supported Tissue enriched 24 bone marrow: 25.8 placenta: 1.0 -DNASE2 DNL, DNL2 ENSG00000105612 Deoxyribonuclease II, lysosomal 19 12875211-12881468 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066185 Supported Expressed in all thyroid gland: 58.9 -MAST1 KIAA0973, SAST ENSG00000105613 Microtubule associated serine/threonine kinase 1 19 12833951-12874951 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028181 Approved Vesicles Tissue enriched 12 cerebral cortex: 35.3 testis: 3.0 -LENG1 ENSG00000105617 Leukocyte receptor cluster (LRC) member 1 19 54155161-54159882 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043541 Uncertain Approved Nucleus
Plasma membrane Tissue enhanced 0 spleen: 1.8 endometrium: 1.0 -PRPF31 hPrp31, NY-BR-99, PRP31, RP11, SNRNP61 ENSG00000105618 Pre-mRNA processing factor 31 19 54115410-54131719 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041939, HPA061873 Supported Supported Nucleus Expressed in all parathyroid gland: 25.9 -TFPT amida, FB1, INO80F ENSG00000105619 TCF3 (E2A) fusion partner (in childhood Leukemia) 19 54107013-54115675 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034958, HPA058534 Approved Supported Nucleoplasm
Nuclear membrane Mixed cerebral cortex: 10.6 -JAK3 JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK ENSG00000105639 Janus kinase 3 19 17824780-17848071 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070314 Supported Approved Cytosol Tissue enhanced 0 appendix: 49.9;lymph node: 47.2 tonsil: 28.2 -RPL18A L18A ENSG00000105640 Ribosomal protein L18a 19 17859876-17864153 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055259 Approved Approved Nucleoli
Cytosol Expressed in all ovary: 3083.8 -SLC5A5 NIS ENSG00000105641 Solute carrier family 5 (sodium/iodide cotransporter), member 5 19 17871973-17895174 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level CAB022364, HPA049055 Supported Tissue enhanced 0 salivary gland: 28.5;stomach: 56.7;thyroid gland: 20.6 cervix: 8.3 -KCNN1 hSK1, KCa2.1 ENSG00000105642 Potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 19 17951293-18000080 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA065938 Approved Actin filaments
Cytosol Tissue enriched 10 cerebral cortex: 21.5 testis: 2.0 -ARRDC2 CLONE24945, PP2703 ENSG00000105643 Arrestin domain containing 2 19 18001132-18014102 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053788 Uncertain Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 51.1 -PIK3R2 p85, P85B ENSG00000105647 Phosphoinositide-3-kinase, regulatory subunit 2 (beta) 19 18153118-18170540 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069291 Approved Approved Golgi apparatus Expressed in all cerebral cortex: 47.4 -RAB3A ENSG00000105649 RAB3A, member RAS oncogene family 19 18196784-18204074 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003160, CAB009949 Supported Approved Nucleoplasm
Centrosome
Cytosol Tissue enriched 12 cerebral cortex: 251.3 adrenal gland: 20.7 -PDE4C DPDE1 ENSG00000105650 Phosphodiesterase 4C, cAMP-specific 19 18207961-18255419 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048975 Approved Mixed endometrium: 7.4 -ISYNA1 Ino1, INOS, IPS ENSG00000105655 Inositol-3-phosphate synthase 1 19 18434388-18438301 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007931, HPA008232, CAB020720 Supported Approved Nucleus
Cytosol Tissue enhanced 0 testis: 117.6 placenta: 63.4 -ELL C19orf17, ELL1, Men, PPP1R68 ENSG00000105656 Elongation factor RNA polymerase II 19 18442663-18522127 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046076 Uncertain Expressed in all testis: 25.3 -CRTC1 FLJ14027, KIAA0616, MECT1, TORC1 ENSG00000105662 CREB regulated transcription coactivator 1 19 18683677-18782333 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022035 Approved Supported Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Expressed in all cerebral cortex: 23.8 -COMP EDM1, EPD1, MED, PSACH, THBS5 ENSG00000105664 Cartilage oligomeric matrix protein 19 18782773-18791314 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 gallbladder: 24.6 smooth muscle: 18.0 -UPK1A TSPAN21 ENSG00000105668 Uroplakin 1A 19 35666516-35678483 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049879 Supported Tissue enhanced 0 esophagus: 27.0;urinary bladder: 112.9 skin: 15.6 -COPE epsilon-COP ENSG00000105669 Coatomer protein complex, subunit epsilon 19 18899514-18919397 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034345, HPA041605, HPA043576 Supported Validated Golgi apparatus Expressed in all testis: 122.8 -DDX49 FLJ10432 ENSG00000105671 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 19 18919675-18928633 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041870, HPA048093 Approved Approved Nucleoli
Mitochondria Expressed in all testis: 24.4 -ETV2 ER71 ENSG00000105672 Ets variant 2 19 35641745-35644871 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 8.8 duodenum: 2.1 -ATP4A ATP6A ENSG00000105675 ATPase, H+/K+ exchanging, alpha polypeptide 19 35550043-35563658 Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039154 Supported Tissue enriched 250 stomach: 537.7 pancreas: 2.1 -ARMC6 MGC19595 ENSG00000105676 Armadillo repeat containing 6 19 19033575-19060311 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041420, HPA041681 Supported Validated Cytosol Expressed in all testis: 28.8 -TMEM147 MGC1936, NIFIE14 ENSG00000105677 Transmembrane protein 147 19 35545595-35547526 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067837 Uncertain Golgi apparatus
Actin filaments
Cytosol Expressed in all thyroid gland: 120.1 -GAPDHS GAPD2, GAPDH-2, GAPDS ENSG00000105679 Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 19 35533412-35545316 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042666 Approved Approved Nucleoplasm
Centrosome Tissue enriched 12 testis: 243.7 thyroid gland: 20.6 -MAG GMA, S-MAG, SIGLEC-4A, SIGLEC4A ENSG00000105695 Myelin associated glycoprotein 19 35292125-35313804 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009345, HPA012499 Supported Tissue enriched 6 cerebral cortex: 164.0 ovary: 27.5 -TMEM59L BSMAP, C19orf4 ENSG00000105696 Transmembrane protein 59-like 19 18607430-18621039 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA010661, HPA070701 Approved Approved Nucleoplasm
Actin filaments Tissue enriched 16 cerebral cortex: 367.2 adrenal gland: 22.3 -HAMP HEPC, HFE2B, LEAP-1, LEAP1 ENSG00000105697 Hepcidin antimicrobial peptide 19 35280716-35285143 Disease related genes, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 7 liver: 257.0 heart muscle: 38.7 -USF2 bHLHb12, FIP ENSG00000105698 Upstream transcription factor 2, c-fos interacting 19 35268978-35279821 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029764, HPA046567 Supported Nucleoplasm
Vesicles Expressed in all cerebral cortex: 216.0 -LSR ILDR3, LISCH7 ENSG00000105699 Lipolysis stimulated lipoprotein receptor 19 35248330-35267964 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007270 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all stomach: 131.1 -KXD1 BORCS4, C19orf50, FLJ25480, KXDL, MGC2749 ENSG00000105700 KxDL motif containing 1 19 18557762-18569387 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041507, HPA041599 Approved Approved Nucleoli fibrillar center
Centrosome
Cytosol Expressed in all appendix: 93.1 -FKBP8 FKBP38, FKBPr38 ENSG00000105701 FK506 binding protein 8, 38kDa 19 18531751-18544077 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025346, HPA045177 Supported Supported Endoplasmic reticulum
Mitochondria
Cytosol Expressed in all cerebral cortex: 355.7 -SUGP1 DKFZp434E2216, F23858, RBP, SF4 ENSG00000105705 SURP and G patch domain containing 1 19 19276018-19320844 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004890 Approved Validated Nucleoplasm Mixed testis: 17.0 -HPN TMPRSS1 ENSG00000105707 Hepsin 19 35040506-35066571 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006804 Approved Tissue enhanced 0 kidney: 99.4;liver: 155.0 prostate: 27.9 -ZNF14 GIOT-4, KOX6 ENSG00000105708 Zinc finger protein 14 19 19710471-19733097 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049863 Uncertain Approved Nucleus
Cytosol Mixed thyroid gland: 13.3 -SCN1B ENSG00000105711 Sodium channel, voltage gated, type I beta subunit 19 35030684-35040448 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skeletal muscle: 133.8 cerebral cortex: 42.7 -PBX4 ENSG00000105717 Pre-B-cell leukemia homeobox 4 19 19561707-19618916 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA049859, HPA056469 Approved Uncertain Vesicles Tissue enhanced 0 testis: 2.6;thyroid gland: 2.2 lymph node: 0.8 -ERF PE-2, PE2 ENSG00000105722 Ets2 repressor factor 19 42247572-42255157 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058532, HPA067952 Approved Validated Nucleoplasm Expressed in all gallbladder: 79.2 -GSK3A ENSG00000105723 Glycogen synthase kinase 3 alpha 19 42230186-42242625 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004422, HPA028423 Approved Approved Cytosol Expressed in all cerebral cortex: 74.7 -ATP13A1 ATP13A, CGI-152, FLJ31858, KIAA1825 ENSG00000105726 ATPase type 13A1 19 19645198-19663693 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031798, HPA049717 Approved Approved Vesicles Expressed in all parathyroid gland: 51.5 -ZNF574 FLJ22059 ENSG00000105732 Zinc finger protein 574 19 42068477-42081565 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023196, HPA057274 Approved Supported Nucleoplasm Expressed in all testis: 40.2 -GRIK5 GluK5, GRIK2, KA2 ENSG00000105737 Glutamate receptor, ionotropic, kainate 5 19 41998321-42069498 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 30.9;parathyroid gland: 21.7 testis: 19.2 -SIPA1L3 KIAA0545 ENSG00000105738 Signal-induced proliferation-associated 1 like 3 19 37907228-38208372 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042072, HPA045480 Uncertain Approved Nuclear membrane
Nuclear speckles Mixed small intestine: 20.2 -ZNF85 HPF4, HTF1 ENSG00000105750 Zinc finger protein 85 19 20923222-20950697 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA044760 Uncertain Supported Nucleus Tissue enhanced 0 testis: 27.8 thyroid gland: 12.0 -ETHE1 HSCO, YF13H12 ENSG00000105755 Ethylmalonic encephalopathy 1 19 43506719-43527244 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028360, HPA029028, HPA029029 Supported Validated Mitochondria Expressed in all colon: 244.2 -CADM4 IGSF4C, Necl-4, SynCAM4, TSLL2 ENSG00000105767 Cell adhesion molecule 4 19 43622368-43639839 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012612 Supported Approved Nucleus
Nuclear membrane Tissue enhanced 0 cerebral cortex: 164.1 parathyroid gland: 58.8 -SMG9 C19orf61, FLJ12886 ENSG00000105771 SMG9 nonsense mediated mRNA decay factor 19 43727992-43754990 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041763, HPA042096 Uncertain Approved Mitochondria
Cytosol Tissue enhanced 0 testis: 48.8 lymph node: 15.0 -AVL9 KIAA0241 ENSG00000105778 AVL9 homolog (S. cerevisiase) 7 32495426-32588721 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050957 Approved Approved Endoplasmic reticulum Expressed in all cerebral cortex: 25.6 -RUNDC3B RPIB9, RPIP9 ENSG00000105784 RUN domain containing 3B 7 87627548-87832296 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056968, HPA057155 Uncertain Tissue enhanced 0 adrenal gland: 9.7 cerebral cortex: 7.2 -CFAP69 C7orf63, FAP69, FLJ21062 ENSG00000105792 Cilia and flagella associated protein 69 7 90245174-90311063 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062883 Uncertain Tissue enhanced 0 prostate: 24.6 fallopian tube: 17.4 -GTPBP10 DKFZP686A10121, FLJ38242 ENSG00000105793 GTP-binding protein 10 (putative) 7 90335223-90391455 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021076 Approved Expressed in all testis: 20.4 -RASA4 CAPRI, GAPL, KIAA0538 ENSG00000105808 RAS p21 protein activator 4 7 102573807-102616757 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043010 Uncertain Uncertain Vesicles Expressed in all skeletal muscle: 84.2 -CDK6 PLSTIRE ENSG00000105810 Cyclin-dependent kinase 6 7 92604921-92836594 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002637, CAB004363 Supported Supported Nucleoplasm
Cytosol Mixed parathyroid gland: 33.5 -PMPCB MPPB, MPPP52 ENSG00000105819 Peptidase (mitochondrial processing) beta 7 103297422-103329511 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040674, HPA074168 Approved Supported Mitochondria Expressed in all parathyroid gland: 68.9 -DNAJC2 MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin ENSG00000105821 DnaJ (Hsp40) homolog, subfamily C, member 2 7 103312474-103344873 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020454 Approved Supported Cytosol Expressed in all testis: 61.7 -TFPI2 PP5, REF1, TFPI-2 ENSG00000105825 Tissue factor pathway inhibitor 2 7 93885397-93890991 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010142, HPA049158 Supported Tissue enriched 23 placenta: 1205.5 ovary: 52.0 -BET1 hbet1 ENSG00000105829 Bet1 golgi vesicular membrane trafficking protein 7 93962762-94004382 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all placenta: 51.4 -NAMPT PBEF, PBEF1 ENSG00000105835 Nicotinamide phosphoribosyltransferase 7 106248285-106286326 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034349, HPA047776, HPA057722 Approved Approved Nuclear speckles
Cell Junctions Expressed in all appendix: 792.4 -TWISTNB ENSG00000105849 TWIST neighbor 7 19695462-19709087 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019071, HPA022416 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all endometrium: 19.6 -PIK3CG ENSG00000105851 Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7 106865278-106907145 Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069976 Supported Plasma membrane Tissue enhanced 0 bone marrow: 28.2 lymph node: 22.2 -PON3 ENSG00000105852 Paraoxonase 3 7 95359944-95396368 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014848, CAB025250 Supported Tissue enriched 8 liver: 327.2 breast: 42.7 -PON2 ENSG00000105854 Paraoxonase 2 7 95404863-95435329 Candidate cardiovascular disease genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025430, HPA029193 Supported Expressed in all cerebral cortex: 226.9 -ITGB8 ENSG00000105855 Integrin, beta 8 7 20330702-20415754 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA027796, HPA027797 Approved Approved Plasma membrane
Cytosol Mixed cerebral cortex: 30.9 -HBP1 ENSG00000105856 HMG-box transcription factor 1 7 107168961-107202529 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020225, CAB032824 Approved Validated Nuclear speckles Expressed in all thyroid gland: 108.7 -DUS4L DUS4, PP35 ENSG00000105865 Dihydrouridine synthase 4-like 7 107563484-107578464 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044301 Approved Approved Cytosol Mixed thyroid gland: 4.8 -SP4 HF1B, MGC130008, MGC130009, SPR-1 ENSG00000105866 Sp4 transcription factor 7 21428034-21514822 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010246, HPA040395 Uncertain Validated Nucleoplasm
Cytosol Mixed parathyroid gland: 14.8 -WDR91 HSPC049 ENSG00000105875 WD repeat domain 91 7 135183839-135211534 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024260 Uncertain Approved Nucleoplasm Mixed fallopian tube: 14.6 -DNAH11 CILD7, DNAHBL, Dnahc11, DNHBL, DPL11 ENSG00000105877 Dynein, axonemal, heavy chain 11 7 21543215-21901839 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045880, HPA056474 Approved Tissue enriched 17 parathyroid gland: 141.9 fallopian tube: 8.4 -CBLL1 FLJ23109, HAKAI, RNF188 ENSG00000105879 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 7 107743697-107761667 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021773, HPA026699 Supported Supported Nuclear speckles Expressed in all testis: 36.0 -DLX5 ENSG00000105880 Distal-less homeobox 5 7 97020392-97025097 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA005670 Approved Uncertain Nucleus Tissue enhanced 0 endometrium: 20.1;placenta: 13.5;skin: 17.2 cervix: 9.5 -MTPN GCDP, MYOTROPHIN, V-1 ENSG00000105887 Myotrophin 7 135926761-135977353 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019735 Approved Approved Plasma membrane
Cytosol Expressed in all cerebral cortex: 194.2 -STEAP1B ENSG00000105889 STEAP family member 1B 7 22419444-22632925 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 5.3 spleen: 3.5 -PTN HBGF8, HBNF, NEGF1 ENSG00000105894 Pleiotrophin 7 137227341-137343865 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017685 Uncertain Tissue enhanced 0 parathyroid gland: 713.3 cerebral cortex: 270.4 -MPP6 p55T, PALS2, VAM-1 ENSG00000105926 Membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) 7 24573268-24694193 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019085, HPA020456 Approved Tissue enhanced 0 gallbladder: 30.0;testis: 45.1 cerebral cortex: 14.9 -DFNA5 ICERE-1 ENSG00000105928 Deafness, autosomal dominant 5 7 24698353-24758113 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011326, CAB019306 Approved Validated Cytosol Mixed placenta: 58.3 -ATP6V0A4 a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2 ENSG00000105929 ATPase, H+ transporting, lysosomal V0 subunit a4 7 138706295-138799560 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018029, HPA064555 Supported Approved Cytosol Group enriched 9 kidney: 69.1;salivary gland: 31.8 breast: 5.5 -ZC3HAV1 FLB6421, FLJ13288, MGC48898, PARP13, ZAP, ZC3H2, ZC3HDC2 ENSG00000105939 Zinc finger CCCH-type, antiviral 1 7 139043520-139109719 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047818, HPA059096 Approved Validated Golgi apparatus
Cytosol Expressed in all bone marrow: 54.7 -TTC26 dyf-13, DYF13, FLJ12571, IFT56 ENSG00000105948 Tetratricopeptide repeat domain 26 7 139133744-139191986 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036338, HPA036339 Supported Approved Nuclear speckles
Intermediate filaments
Cytosol Tissue enhanced 0 fallopian tube: 22.4;testis: 22.0 parathyroid gland: 13.3 -OGDH E1k ENSG00000105953 Oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 7 44606572-44709066 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019514, HPA020347 Supported Validated Mitochondria Expressed in all heart muscle: 146.5 -NPVF C7orf9, RFRP ENSG00000105954 Neuropeptide VF precursor 7 25224570-25228486 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041733 Approved Not detected tonsil: 0.3 -ADAP1 CENTA1, GCS1L ENSG00000105963 ArfGAP with dual PH domains 1 7 897901-955407 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007033, HPA012049 Supported Supported Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 80.5 colon: 38.9 -TFEC bHLHe34, TCFEC, TFECL ENSG00000105967 Transcription factor EC 7 115935148-116159896 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB032260, HPA063577 Approved Supported Nucleoplasm Mixed appendix: 27.1 -H2AFV H2AV, MGC10170, MGC10831, MGC1947 ENSG00000105968 H2A histone family, member V 7 44826791-44848083 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA057236 Supported Expressed in all bone marrow: 219.0 -CAV2 CAV ENSG00000105971 Caveolin 2 7 116287380-116508541 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013488, HPA044810 Supported Approved Vesicles Mixed adipose tissue: 233.3 -CAV1 CAV ENSG00000105974 Caveolin 1, caveolae protein, 22kDa 7 116524785-116561184 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003791, HPA049326 Supported Supported Golgi apparatus Tissue enhanced 0 lung: 860.5 adipose tissue: 638.7 -MET DFNB97, HGFR, RCCP2 ENSG00000105976 MET proto-oncogene, receptor tyrosine kinase 7 116672390-116798386 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005282, CAB018577, HPA055607 Uncertain Supported Plasma membrane
Cytosol Mixed placenta: 38.7 -RNF32 FKSG33, HSD15, LMBR2 ENSG00000105982 Ring finger protein 32 7 156640281-156677130 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA073560 Supported Tissue enriched 8 testis: 110.0 epididymis: 13.7 -LMBR1 ACHP, C7orf2, FLJ11665, ZRS ENSG00000105983 Limb development membrane protein 1 7 156668946-156893230 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016592 Approved Approved Cytosol Expressed in all parathyroid gland: 45.4 -WNT2 INT1L1, IRP ENSG00000105989 Wingless-type MMTV integration site family member 2 7 117276631-117323289 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA020920 Approved Vesicles Group enriched 6 endometrium: 23.6;placenta: 92.5 lung: 9.2 -HOXA1 HOX1, HOX1F ENSG00000105991 Homeobox A1 7 27092993-27095996 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 urinary bladder: 8.7 parathyroid gland: 2.7 -DNAJB6 LGMD1D, MRJ ENSG00000105993 DnaJ (Hsp40) homolog, subfamily B, member 6 7 157335381-157417439 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004670, HPA024258, HPA058593 Supported Supported Nucleoplasm Expressed in all testis: 219.6 -HOXA2 HOX1K ENSG00000105996 Homeobox A2 7 27100354-27102811 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA078220 Approved Nucleus
Vesicles Tissue enhanced 0 parathyroid gland: 8.1 epididymis: 6.1 -HOXA3 HOX1, HOX1E ENSG00000105997 Homeobox A3 7 27106184-27152581 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA029157 Uncertain Supported Nucleoplasm Tissue enhanced 0 fallopian tube: 25.4 parathyroid gland: 11.3 -LFNG SCDO3 ENSG00000106003 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 7 2512529-2529177 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069130 Approved Expressed in all skin: 68.6 -HOXA5 HOX1, HOX1C ENSG00000106004 Homeobox A5 7 27141052-27143668 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029319 Uncertain Tissue enhanced 0 adrenal gland: 110.5;epididymis: 59.1 fallopian tube: 43.5 -HOXA6 HOX1, HOX1B ENSG00000106006 Homeobox A6 7 27145396-27150603 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA004203 Approved Tissue enhanced 0 fallopian tube: 10.1 endometrium: 9.0 -BRAT1 BAAT1, C7orf27, MGC22916 ENSG00000106009 BRCA1-associated ATM activator 1 7 2537877-2555727 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029455, HPA076508 Approved Supported Nucleoplasm Expressed in all testis: 14.9 -IQCE KIAA1023 ENSG00000106012 IQ motif containing E 7 2558972-2614734 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019515 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 51.4 fallopian tube: 23.6 -ANKRD7 TSA806 ENSG00000106013 Ankyrin repeat domain 7 7 118214669-118496171 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043489 Approved Nucleus Tissue enriched 569 testis: 1533.6 epididymis: 2.6 -VIPR2 VPAC2, VPAC2R ENSG00000106018 Vasoactive intestinal peptide receptor 2 7 159028175-159144957 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062707 Approved Tissue enhanced 0 seminal vesicle: 28.2 epididymis: 14.8 -TSPAN12 NET-2, TM4SF12 ENSG00000106025 Tetraspanin 12 7 120787320-120858402 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051570, HPA058244 Uncertain Approved Vesicles
Microtubules Mixed kidney: 90.9 -SSBP1 mtSSB, SSBP ENSG00000106028 Single-stranded DNA binding protein 1, mitochondrial 7 141738321-141787922 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002866 Supported Supported Mitochondria Expressed in all testis: 147.1 -HOXA13 HOX1, HOX1J ENSG00000106031 Homeobox A13 7 27193503-27200106 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046098 Approved Nucleoplasm
Intermediate filaments Tissue enhanced 0 cervix, uterine: 33.9;placenta: 24.3;prostate: 36.5;seminal vesicle: 32.2 rectum: 13.3 -CPED1 C7orf58, FLJ21986 ENSG00000106034 Cadherin-like and PC-esterase domain containing 1 7 120988677-121297444 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA012058 Uncertain Approved Nucleus Mixed ovary: 96.3 -EVX1 ENSG00000106038 Even-skipped homeobox 1 7 27242700-27250493 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055132 Approved Nucleoplasm Tissue enhanced 0 adrenal gland: 3.7;prostate: 4.6;seminal vesicle: 4.3 testis: 1.5 -HIBADH NS5ATP1 ENSG00000106049 3-hydroxyisobutyrate dehydrogenase 7 27525442-27662995 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019522, HPA021002 Supported Expressed in all kidney: 112.0 -TAX1BP1 CALCOCO3, TXBP151 ENSG00000106052 Tax1 (human T-cell leukemia virus type I) binding protein 1 7 27739331-27844564 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024432 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 181.0 -CPVL ENSG00000106066 Carboxypeptidase, vitellogenic-like 7 28995231-29195451 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003697, HPA045715, HPA056466 Supported Supported Endoplasmic reticulum Expressed in all spleen: 397.9 -CHN2 ARHGAP3, RhoGAP3 ENSG00000106069 Chimerin 2 7 29122274-29514328 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018989 Approved Tissue enhanced 0 duodenum: 76.8;small intestine: 69.8 cerebral cortex: 31.8 -GRB10 ENSG00000106070 Growth factor receptor-bound protein 10 7 50590063-50793462 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB019423, HPA027502, HPA031818 Approved Approved Nuclear membrane
Vesicles Expressed in all thyroid gland: 44.8 -ABHD11 PP1226, WBSCR21 ENSG00000106077 Abhydrolase domain containing 11 7 73736094-73738867 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024042, HPA049641 Approved Supported Mitochondria Expressed in all thyroid gland: 28.6 -COBL KIAA0633 ENSG00000106078 Cordon-bleu WH2 repeat protein 7 51016212-51316818 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019033, HPA019167 Supported Approved Plasma membrane
Cell Junctions Mixed cerebral cortex: 61.6 -FKBP14 FKBP22, FLJ20731 ENSG00000106080 FK506 binding protein 14, 22 kDa 7 30010587-30026684 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013329, HPA026829 Uncertain Approved Nucleus
Golgi apparatus
Cytosol Mixed smooth muscle: 20.1 -PLEKHA8 FAPP2, MGC3358 ENSG00000106086 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 7 30027404-30130483 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072314 Supported Nucleoplasm
Golgi apparatus Mixed placenta: 11.5 -STX1A HPC-1, p35-1, STX1 ENSG00000106089 Syntaxin 1A (brain) 7 73699206-73719672 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008372, HPA069176 Supported Tissue enriched 15 cerebral cortex: 167.1 gallbladder: 10.8 -NOD1 CARD4, CLR7.1, NLRC1 ENSG00000106100 Nucleotide-binding oligomerization domain containing 1 7 30424527-30478784 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA074367 Approved Mitochondria Mixed lung: 17.9 -GARS CMT2D, DSMAV, GlyRS, SMAD1 ENSG00000106105 Glycyl-tRNA synthetase 7 30594681-30634033 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017896, HPA019097 Supported Supported Cytosol Expressed in all parathyroid gland: 94.3 -CRHR2 CRF-RB, CRF2, HM-CRF ENSG00000106113 Corticotropin releasing hormone receptor 2 7 30651943-30700129 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046683 Uncertain Tissue enhanced 0 seminal vesicle: 1.8 cerebral cortex: 1.2 -EPHB6 HEP ENSG00000106123 EPH receptor B6 7 142855061-142871094 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035784 Approved Nuclear speckles Tissue enhanced 0 cerebral cortex: 22.6;skin: 25.0 cervix: 7.5 -FAM188B C7orf67, FLJ22374 ENSG00000106125 Family with sequence similarity 188, member B 7 30771417-30892387 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019475, HPA030129, HPA030130 Approved Supported Vesicles
Cytosol Mixed fallopian tube: 18.4 -GHRHR ENSG00000106128 Growth hormone releasing hormone receptor 7 30938669-30993254 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level No evidence Evidence at protein level Not detected adrenal gland: 0.5 -CASP2 ICH1, MGC2181, NEDD2, PPP1R57 ENSG00000106144 Caspase 2, apoptosis-related cysteine peptidase 7 143288215-143307696 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB012175, HPA050678 Approved Approved Nucleoplasm Expressed in all lymph node: 25.3 -CHCHD2 C7orf17 ENSG00000106153 Coiled-coil-helix-coiled-coil-helix domain containing 2 7 56101569-56106576 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027407, HPA052510 Uncertain Validated Mitochondria Expressed in all adrenal gland: 588.3 -CCL24 Ckb-6, eotaxin-2, MPIF-2, MPIF2, SCYA24 ENSG00000106178 Chemokine (C-C motif) ligand 24 7 75811665-75823356 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 rectum: 113.4;small intestine: 98.1 urinary bladder: 53.6 -HSPB1 CMT2F, Hs.76067, Hsp25, HSP27, HSP28 ENSG00000106211 Heat shock 27kDa protein 1 7 76302544-76304295 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000497, CAB004439, CAB047330, CAB047331, CAB047332 Supported Validated Plasma membrane
Cytosol Expressed in all esophagus: 1622.3 -NPTX2 ENSG00000106236 Neuronal pentraxin II 7 98617297-98629868 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020801, HPA049799 Supported Tissue enhanced 0 adrenal gland: 33.6;cerebral cortex: 80.5;testis: 44.4 cervix: 12.0 -PDAP1 HASPP28, PAP, PAP1 ENSG00000106244 PDGFA associated protein 1 7 99392048-99408829 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021103, HPA050294, HPA060836 Approved Validated Plasma membrane
Cytosol Expressed in all skeletal muscle: 37.3 -BUD31 Cwc14, EDG-2, EDG2, fSAP17, G10, YCR063W ENSG00000106245 BUD31 homolog 7 99408641-99419616 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028943 Approved Approved Nucleus
Microtubules
Centrosome Expressed in all testis: 101.5 -PTCD1 KIAA0632 ENSG00000106246 Pentatricopeptide repeat domain 1 7 99416739-99466163 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA020106, HPA047679 Uncertain Approved Mitochondria Mixed skin: 5.1 -CYP3A5 CP35, P450PCN3, PCN3 ENSG00000106258 Cytochrome P450, family 3, subfamily A, polypeptide 5 7 99648194-99679998 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072245 Uncertain Cytosol Tissue enhanced 0 duodenum: 117.9;liver: 93.1;small intestine: 191.3 stomach: 79.3 -ZKSCAN1 KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33 ENSG00000106261 Zinc finger with KRAB and SCAN domains 1 7 100015572-100041689 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006672 Uncertain Approved Nucleus
Nuclear bodies
Mitochondria Expressed in all skin: 39.1 -EIF3B eIF3b, EIF3S9, PRT1 ENSG00000106263 Eukaryotic translation initiation factor 3, subunit B 7 2354086-2380745 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017562, HPA048983 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 102.9 -SNX8 Mvp1 ENSG00000106266 Sorting nexin 8 7 2251770-2354318 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057296, HPA060194 Approved Supported Vesicles Expressed in all spleen: 38.7 -NUDT1 MTH1 ENSG00000106268 Nudix (nucleoside diphosphate linked moiety X)-type motif 1 7 2242222-2251146 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012636 Approved Approved Cytosol Expressed in all testis: 50.7 -PTPRZ1 phosphacan, PTP18, PTPRZ, PTPZ, RPTPB ENSG00000106278 Protein tyrosine phosphatase, receptor-type, Z polypeptide 1 7 121873089-122062036 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015103, CAB025106 Supported Approved Vesicles Tissue enriched 9 cerebral cortex: 258.6 skin: 30.2 -TAF6 MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85 ENSG00000106290 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 7 100107070-100119841 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006566 Uncertain Supported Nucleus
Cytosol Expressed in all testis: 62.7 -WASL N-WASP, NWASP, WASPB ENSG00000106299 Wiskott-Aldrich syndrome-like 7 123681935-123749067 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005399, HPA005750 Supported Approved Nucleoli
Cytosol Expressed in all parathyroid gland: 72.6 -HYAL4 ENSG00000106302 Hyaluronoglucosaminidase 4 7 123828983-123877478 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029453 Uncertain Tissue enhanced 0 placenta: 5.9;testis: 4.0 epididymis: 2.1 -SPAM1 HYAL5, PH-20, SPAG15 ENSG00000106304 Sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 7 123925237-123971414 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017984 Supported Tissue enriched 63 testis: 30.0 small intestine: 0.4 -AIMP2 JTV-1, JTV1, p38, PRO0992 ENSG00000106305 Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 7 6009245-6023834 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019098, HPA020057 Supported Approved Cytosol Expressed in all testis: 60.7 -TFR2 HFE3, TFRC2 ENSG00000106327 Transferrin receptor 2 7 100620416-100642779 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011937, CAB016255 Supported Tissue enriched 11 liver: 155.8 bone marrow: 13.9 -FSCN3 ENSG00000106328 Fascin actin-bundling protein 3, testicular 7 127591409-127602144 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 244 testis: 105.3 skin: 0.4 -MOSPD3 CDS3, NET30 ENSG00000106330 Motile sperm domain containing 3 7 100612102-100615384 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA041137, HPA048240 Uncertain Approved Nucleoplasm
Cytosol Expressed in all testis: 29.7 -PAX4 MODY9 ENSG00000106331 Paired box 4 7 127610292-127615928 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 duodenum: 1.2;rectum: 1.3 testis: 0.6 -PCOLCE PCPE, PCPE1 ENSG00000106333 Procollagen C-endopeptidase enhancer 7 100602177-100608175 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017623, HPA042927 Approved Approved Golgi apparatus
Vesicles Tissue enhanced 0 cervix, uterine: 215.7 gallbladder: 146.7 -FBXO24 FBX24 ENSG00000106336 F-box protein 24 7 100583982-100601117 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050951 Approved Tissue enriched 25 testis: 71.5 ovary: 2.8 -PPP1R17 C7orf16, GSBS ENSG00000106341 Protein phosphatase 1, regulatory subunit 17 7 31686715-31708455 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047819 Supported Group enriched 5 adrenal gland: 4.9;cerebral cortex: 2.6;testis: 1.1 lung: 0.5 -RBM28 FLJ10377 ENSG00000106344 RNA binding motif protein 28 7 128297685-128343908 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019058, HPA026672, HPA031519 Supported Validated Nucleoli Expressed in all testis: 26.8 -USP42 FLJ12697 ENSG00000106346 Ubiquitin specific peptidase 42 7 6104884-6161564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006752, HPA064800 Uncertain Approved Nucleus Tissue enhanced 0 testis: 27.6 parathyroid gland: 8.6 -IMPDH1 LCA11, RP10, sWSS2608 ENSG00000106348 IMP (inosine 5'-monophosphate) dehydrogenase 1 7 128392277-128410252 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001400 Approved Supported Cytosol
Rods & Rings Expressed in all appendix: 47.2 -AGFG2 HRBL, RABR ENSG00000106351 ArfGAP with FG repeats 2 7 100539211-100568219 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019689 Approved Tissue enriched 6 salivary gland: 128.0 skin: 22.8 -LSM5 YER146W ENSG00000106355 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated 7 32485332-32495283 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019054 Uncertain Expressed in all breast: 76.9 -SERPINE1 PAI, PAI1, PLANH1 ENSG00000106366 Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 7 101127089-101139266 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050039 Approved Approved Cytosol Tissue enhanced 0 gallbladder: 581.0;placenta: 595.2 adipose tissue: 213.2 -AP1S1 AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2 ENSG00000106367 Adaptor-related protein complex 1, sigma 1 subunit 7 101154397-101161596 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060945 Supported Supported Golgi apparatus
Vesicles Expressed in all cerebral cortex: 107.3 -MOGAT3 DC7, MGAT3 ENSG00000106384 Monoacylglycerol O-acyltransferase 3 7 101195007-101201021 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA011940 Uncertain Approved Centrosome Group enriched 6 colon: 11.5;duodenum: 31.2;rectum: 12.0;small intestine: 34.2 liver: 3.4 -C1GALT1 C1GALT, T-synthase ENSG00000106392 Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 7 7156934-7248651 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011294, HPA012819 Supported Approved Nuclear bodies
Cytosol Expressed in all parathyroid gland: 93.3 -PLOD3 LH3 ENSG00000106397 Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 7 101205977-101218420 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001236 Uncertain Expressed in all placenta: 48.0 -RPA3 REPA3 ENSG00000106399 Replication protein A3, 14kDa 7 7636518-7718607 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005708 Approved Expressed in all parathyroid gland: 50.6 -ZNHIT1 CG1I, H_DJ0747G18.14, ZNFN4A1 ENSG00000106400 Zinc finger, HIT-type containing 1 7 101217668-101224190 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019043 Uncertain Approved Nucleoplasm Expressed in all liver: 50.5 -CLDN15 ENSG00000106404 Claudin 15 7 101232092-101238820 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 16 duodenum: 248.2;small intestine: 187.4 spleen: 13.5 -NOBOX OG2, Og2x ENSG00000106410 NOBOX oogenesis homeobox 7 144397240-144410227 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.7 -GLCCI1 FAM117C, GIG18, TSSN1 ENSG00000106415 Glucocorticoid induced 1 7 7968794-8094272 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001674, HPA005987 Approved Uncertain Nucleoli Mixed thyroid gland: 28.1 -MYL10 MGC3479, MYLC2PL, PLRLC ENSG00000106436 Myosin, light chain 10, regulatory 7 101613325-101629296 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA019763 Uncertain Uncertain Microtubules Not detected placenta: 0.7 -PHF14 KIAA0783 ENSG00000106443 PHD finger protein 14 7 10973872-11169630 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000538 Supported Expressed in all parathyroid gland: 20.6 -NRF1 ALPHA-PAL, EWG ENSG00000106459 Nuclear respiratory factor 1 7 129611714-129757082 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029329 Approved Supported Nucleoplasm
Cytosol Expressed in all fallopian tube: 20.7 -TMEM106B FLJ11273, MGC33727 ENSG00000106460 Transmembrane protein 106B 7 12211241-12243367 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058342 Approved Supported Endosomes
Lysosomes Expressed in all thyroid gland: 64.7 -EZH2 ENX-1, EZH1, KMT6, KMT6A ENSG00000106462 Enhancer of zeste 2 polycomb repressive complex 2 subunit 7 148807383-148884321 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009589, HPA029131 Supported Supported Nucleoplasm Tissue enhanced 0 testis: 50.4 bone marrow: 30.0 -CEP41 DKFZp762H1311, FLJ22445, JBTS15, TSGA14 ENSG00000106477 Centrosomal protein 41kDa 7 130393771-130442433 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024090 Uncertain Tissue enhanced 0 testis: 80.0 salivary gland: 18.2 -ZNF862 ENSG00000106479 Zinc finger protein 862 7 149838367-149867479 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA024154 Uncertain Approved Mitochondria Expressed in all parathyroid gland: 23.5 -SFRP4 FRP-4, frpHE ENSG00000106483 Secreted frizzled-related protein 4 7 37905932-38025695 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009712, HPA050585 Supported Group enriched 5 cervix, uterine: 931.0;endometrium: 772.5;fallopian tube: 335.6 smooth muscle: 129.2 -MEST PEG1 ENSG00000106484 Mesoderm specific transcript 7 130486171-130506296 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA005623 Approved Golgi apparatus
Cytosol Tissue enriched 8 placenta: 1079.4 adipose tissue: 131.7 -MEOX2 GAX, MOX2 ENSG00000106511 Mesenchyme homeobox 2 7 15611212-15686812 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053793 Supported Tissue enhanced 0 adipose tissue: 28.5;placenta: 57.2 lung: 10.9 -ANKMY2 DKFZP564O043, ZMYND20 ENSG00000106524 Ankyrin repeat and MYND domain containing 2 7 16599776-16645817 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044900, HPA050447, HPA067100 Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 34.4 -ACTR3C ARP11 ENSG00000106526 ARP3 actin-related protein 3 homolog C (yeast) 7 150243916-150323725 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055957 Uncertain Tissue enriched 5 parathyroid gland: 85.6 adrenal gland: 15.9 -POU6F2 RPF-1 ENSG00000106536 POU class 6 homeobox 2 7 38977998-39493095 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA008699 Uncertain Tissue enhanced 0 cerebral cortex: 3.1;placenta: 1.8 testis: 1.2 -TSPAN13 NET-6, TM4SF13 ENSG00000106537 Tetraspanin 13 7 16753535-16784536 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA007426 Uncertain Approved Nucleus Expressed in all lung: 246.3 -RARRES2 HP10433, TIG2 ENSG00000106538 Retinoic acid receptor responder (tazarotene induced) 2 7 150338317-150341674 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049359 Uncertain Cytosol Tissue enhanced 0 adrenal gland: 1529.4 parathyroid gland: 904.5 -AGR2 AG2, HAG-2, PDIA17, XAG-2 ENSG00000106541 Anterior gradient 2, protein disulphide isomerase family member 7 16791811-16833433 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007912 Supported Approved Cytosol Tissue enhanced 0 rectum: 1341.6;stomach: 1313.5 cervix: 933.1 -AHR bHLHe76 ENSG00000106546 Aryl hydrocarbon receptor 7 17298622-17346152 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005072, HPA029722, HPA029723 Supported Validated Nucleoplasm
Cytosol Mixed urinary bladder: 57.6 -CHCHD3 FLJ20420, Mic19, MINOS3, PPP1R22 ENSG00000106554 Coiled-coil-helix-coiled-coil-helix domain containing 3 7 132784868-133082088 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042935 Supported Supported Mitochondria Expressed in all skeletal muscle: 121.2 -GIMAP2 DKFZp586D0824, HIMAP2, IAN12, IMAP2 ENSG00000106560 GTPase, IMAP family member 2 7 150685697-150693641 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013589 Approved Mixed lymph node: 89.2 -TMEM176B LR8, MS4B2 ENSG00000106565 Transmembrane protein 176B 7 150791285-150801360 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047509 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Expressed in all liver: 842.9 -GLI3 ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV ENSG00000106571 GLI family zinc finger 3 7 41960950-42237870 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005534 Approved Mixed endometrium: 15.8 -PSMA2 HC3, MU, PMSA2 ENSG00000106588 Proteasome subunit alpha 2 7 42916857-42932223 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008188 Uncertain Expressed in all liver: 164.2 -MRPL32 bMRP-59b, HSPC283, L32mt, MRP-L32 ENSG00000106591 Mitochondrial ribosomal protein L32 7 42932200-42948958 Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048965 Uncertain Expressed in all prostate: 73.2 -COA1 C7orf44, FLJ10803, MITRAC15 ENSG00000106603 Cytochrome c oxidase assembly factor 1 homolog 7 43608456-43729717 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011944 Approved Supported Mitochondria Expressed in all lymph node: 36.9 -BLVRA BLVR ENSG00000106605 Biliverdin reductase A 7 43758680-43807342 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019709, HPA042865, HPA054322 Approved Supported Cytosol Expressed in all epididymis: 155.8 -URGCP DKFZp666G166, DKFZp686O0457, FLJ20654, KIAA1507, URG4 ENSG00000106608 Upregulator of cell proliferation 7 43875894-43926411 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019879, HPA020134, HPA029468 Approved Supported Cytosol Expressed in all parathyroid gland: 33.8 -TMEM248 C7orf42, FLJ10099, FLJ13090 ENSG00000106609 Transmembrane protein 248 7 66921225-66958551 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016495 Uncertain Approved Vesicles Expressed in all parathyroid gland: 92.0 -RHEB RHEB2 ENSG00000106615 Ras homolog enriched in brain 7 151466012-151520120 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB019436 Uncertain Expressed in all cerebral cortex: 207.8 -PRKAG2 AAKG, AAKG2, CMH6, H91620p, WPWS ENSG00000106617 Protein kinase, AMP-activated, gamma 2 non-catalytic subunit 7 151556111-151877125 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004246, CAB018641 Uncertain Approved Nucleoplasm Expressed in all heart muscle: 94.9 -AEBP1 ACLP ENSG00000106624 AE binding protein 1 7 44104361-44114562 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009966, HPA047724, HPA063595, HPA064970 Supported Supported Nucleoplasm
Vesicles
Cytosol Expressed in all seminal vesicle: 297.8 -POLD2 ENSG00000106628 Polymerase (DNA directed), delta 2, accessory subunit 7 44114681-44124358 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026745 Approved Validated Nucleoplasm Expressed in all fallopian tube: 121.0 -MYL7 MYL2A, MYLC2A ENSG00000106631 Myosin, light chain 7, regulatory 7 44138864-44141332 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013331, CAB033884, HPA039262 Supported Tissue enriched 1460 heart muscle: 9298.4 breast: 6.3 -GCK HK4, MODY2 ENSG00000106633 Glucokinase (hexokinase 4) 7 44144271-44198170 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007034, HPA007093 Approved Approved Golgi apparatus
Cytosol Mixed cerebral cortex: 2.5 -BCL7B ENSG00000106635 B-cell CLL/lymphoma 7B 7 73536356-73558002 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049943, HPA058069 Approved Approved Nucleoplasm Expressed in all bone marrow: 24.8 -YKT6 ENSG00000106636 YKT6 v-SNARE homolog (S. cerevisiae) 7 44200968-44214294 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030817, HPA030818 Approved Approved Mitochondria
Cytosol Expressed in all cerebral cortex: 62.0 -TBL2 DKFZP43N024, WBSCR13, WS-betaTRP ENSG00000106638 Transducin (beta)-like 2 7 73568932-73578791 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007477, HPA051533 Supported Cytosol Tissue enriched 6 testis: 83.4 parathyroid gland: 13.0 -GALNTL5 GalNAc-T5L, GALNT15 ENSG00000106648 Polypeptide N-acetylgalactosaminyltransferase-like 5 7 151956379-152019934 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA011140 Supported Tissue enriched 14 testis: 11.1 cerebral cortex: 0.8 -CLIP2 CLIP, CLIP-115, CYLN2, KIAA0291, WBSCR3, WBSCR4, WSCR3, WSCR4 ENSG00000106665 CAP-GLY domain containing linker protein 2 7 74289475-74405943 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020430, CAB020767 Supported Tissue enhanced 0 cerebral cortex: 76.0 ovary: 20.9 -EIF4H KIAA0038, WBSCR1, WSCR1 ENSG00000106682 Eukaryotic translation initiation factor 4H 7 74174245-74197101 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030542 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all parathyroid gland: 249.7 -LIMK1 LIMK ENSG00000106683 LIM domain kinase 1 7 74082933-74122525 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028064, HPA028516 Approved Supported Nuclear speckles
Cytosol Expressed in all cerebral cortex: 39.6 -SPATA6L C9orf68, FLJ10058 ENSG00000106686 Spermatogenesis associated 6-like 9 4553386-4666674 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039585 Supported Tissue enhanced 0 fallopian tube: 5.7;testis: 6.3 gallbladder: 2.3 -SLC1A1 EAAC1, EAAT3 ENSG00000106688 Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 9 4490444-4587469 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015466, HPA020086 Approved Tissue enhanced 0 small intestine: 72.7 epididymis: 53.8 -LHX2 hLhx2, LH-2 ENSG00000106689 LIM homeobox 2 9 124001670-124033301 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000838 Supported Approved Nucleoplasm Tissue enriched 11 cerebral cortex: 56.4 placenta: 5.1 -FKTN FCMD, LGMD2M ENSG00000106692 Fukutin 9 105558130-105641118 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012820 Approved Expressed in all parathyroid gland: 17.0 -FSD1L CCDC10, CSDUFD1, FSD1CL, FSD1NL ENSG00000106701 Fibronectin type III and SPRY domain containing 1-like 9 105447796-105552433 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035138 Approved Approved Plasma membrane
Actin filaments Tissue enhanced 0 cerebral cortex: 17.8 testis: 13.4 -CNTNAP3 CASPR3, CNTNAP3A, FLJ14195, KIAA1714 ENSG00000106714 Contactin associated protein-like 3 9 39072767-39288315 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015604, HPA047731 Approved Mixed esophagus: 8.3 -SPIN1 SPIN, TDRD24 ENSG00000106723 Spindlin 1 9 88388419-88478694 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000162, HPA068784 Uncertain Supported Nucleoplasm Expressed in all endometrium: 101.1 -NMRK1 bA235O14.2, C9orf95, FLJ20559, NRK1 ENSG00000106733 Nicotinamide riboside kinase 1 9 75060573-75088217 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049795 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 118.5 -TMEM245 C9orf5, CG-2 ENSG00000106771 Transmembrane protein 245 9 109015152-109119945 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023892 Approved Approved Plasma membrane
Cytosol Expressed in all thyroid gland: 123.5 -PRUNE2 A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367 ENSG00000106772 Prune homolog 2 (Drosophila) 9 76611376-76906087 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022470, HPA031079 Uncertain Mixed seminal vesicle: 89.2 -MEGF9 EGFL5 ENSG00000106780 Multiple EGF-like-domains 9 9 120600813-120714470 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014319, HPA050238 Uncertain Approved Nucleus
Cytosol Expressed in all thyroid gland: 47.1 -TRIM14 KIAA0129 ENSG00000106785 Tripartite motif containing 14 9 98069275-98119212 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA053217 Uncertain Approved Nucleoplasm
Cytosol Mixed parathyroid gland: 37.0 -CORO2A IR10, WDR2 ENSG00000106789 Coronin, actin binding protein, 2A 9 98120975-98192640 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041161, HPA041302 Supported Approved Plasma membrane
Cytosol Mixed small intestine: 39.4 -TGFBR1 ACVRLK4, ALK-5, ESS1, MSSE ENSG00000106799 Transforming growth factor, beta receptor 1 9 99104038-99154192 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002441, CAB031481, HPA056473 Uncertain Supported Vesicles
Plasma membrane Expressed in all placenta: 69.3 -SEC61B ENSG00000106803 Sec61 translocon beta subunit 9 99222064-99230615 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049407 Approved Validated Endoplasmic reticulum Expressed in all epididymis: 333.0 -C5 C5a, C5b, CPAMD4 ENSG00000106804 Complement component 5 9 120952335-121050276 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029339 Uncertain Tissue enriched 21 liver: 225.4 lung: 10.5 -OGN mimecan, OIF, SLRR3A ENSG00000106809 Osteoglycin 9 92383967-92404696 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013132 Approved Supported Endoplasmic reticulum Tissue enhanced 0 cervix, uterine: 372.2;parathyroid gland: 593.1 gallbladder: 277.6 -ASPN FLJ20129, PLAP1, SLRR1C ENSG00000106819 Asporin 9 92456205-92482506 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008435, HPA024230 Approved Supported Nucleoplasm
Vesicles Tissue enhanced 0 endometrium: 114.7;smooth muscle: 159.0 gallbladder: 104.4 -ECM2 ENSG00000106823 Extracellular matrix protein 2, female organ and adipocyte specific 9 92493554-92536655 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035347 Approved Mixed adipose tissue: 128.3 -TLE4 E(spI), ESG, GRG4 ENSG00000106829 Transducin-like enhancer of split 4 9 79571773-79726882 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065357 Supported Nucleus Expressed in all testis: 201.5 -LHX6 LHX6.1 ENSG00000106852 LIM homeobox 6 9 122202577-122229626 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA047854, HPA058319 Approved Uncertain Nucleoli fibrillar center
Plasma membrane Mixed cerebral cortex: 8.1 -PTGR1 LTB4DH, ZADH3 ENSG00000106853 Prostaglandin reductase 1 9 111549722-111599855 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036724 Supported Expressed in all small intestine: 321.1 -SUSD1 DKFZP761E1824 ENSG00000106868 Sushi domain containing 1 9 112040785-112175408 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048554 Approved Approved Nucleoplasm Mixed placenta: 21.3 -AMBP EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI ENSG00000106927 Alpha-1-microglobulin/bikunin precursor 9 114060127-114078472 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001497, CAB069436 Approved Tissue enriched 22 liver: 5152.3 gallbladder: 231.0 -AKNA KIAA1968 ENSG00000106948 AT-hook transcription factor 9 114334156-114394405 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052367, HPA063993 Supported Nucleoplasm
Centrosome Mixed spleen: 97.3 -TNFSF8 CD153, CD30LG ENSG00000106952 Tumor necrosis factor (ligand) superfamily, member 8 9 114893343-114930595 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 lymph node: 34.8;tonsil: 27.8 appendix: 25.1 -DNM1 DNM ENSG00000106976 Dynamin 1 9 128203352-128255248 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005920, HPA049910, HPA061801 Supported Supported Nucleoplasm Tissue enriched 14 cerebral cortex: 365.7 cervix: 25.2 -ENG CD105, END, HHT1, ORW, ORW1 ENSG00000106991 Endoglin 9 127815012-127854756 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000096, HPA011862, HPA067440, CAB072873 Supported Expressed in all spleen: 170.7 -AK1 ENSG00000106992 Adenylate kinase 1 9 127866480-127877743 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006456, CAB009893 Supported Supported Cytosol Expressed in all fallopian tube: 764.1 -CDC37L1 CDC37B, FLJ20639, HARC ENSG00000106993 Cell division cycle 37-like 1 9 4679559-4708398 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021175 Approved Supported Cytosol Expressed in all liver: 28.5 -RLN2 bA12D24.1.1, bA12D24.1.2, H2, RLXH2 ENSG00000107014 Relaxin 2 9 5299868-5304969 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 fallopian tube: 8.0 prostate: 5.4 -RLN1 H1 ENSG00000107018 Relaxin 1 9 5334969-5339873 Plasma proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 54 prostate: 33.4 testis: 0.6 -PLGRKT AD025, C9orf46, FLJ14688, MDS030, Plg-RKT ENSG00000107020 Plasminogen receptor, C-terminal lysine transmembrane protein 9 5357973-5437878 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008214, HPA011144 Approved Uncertain Mitochondria Expressed in all rectum: 56.0 -TBC1D13 FLJ10743 ENSG00000107021 TBC1 domain family, member 13 9 128787204-128810432 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045865 Approved Approved Nucleoli Expressed in all parathyroid gland: 46.3 -RIC1 bA207C16.1, KIAA1432 ENSG00000107036 RIC1 homolog, RAB6A GEF complex partner 1 9 5629025-5776557 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051578 Supported Expressed in all parathyroid gland: 22.1 -KDM4C GASC1, JMJD2C, KIAA0780, TDRD14C ENSG00000107077 Lysine (K)-specific demethylase 4C 9 6757641-7175648 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069357 Approved Nucleoplasm Expressed in all parathyroid gland: 34.4 -DOCK8 FLJ00026, FLJ00152, FLJ00346, ZIR8 ENSG00000107099 Dedicator of cytokinesis 8 9 214854-465259 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003218 Approved Uncertain Nucleoplasm
Centrosome
Mitochondria
Cytosol Mixed spleen: 63.0 -KANK1 ANKRD15, KANK, KIAA0172 ENSG00000107104 KN motif and ankyrin repeat domains 1 9 470291-746106 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005539, HPA056090 Approved Supported Plasma membrane Mixed smooth muscle: 54.8 -ELAVL2 HEL-N1, HuB ENSG00000107105 ELAV like neuron-specific RNA binding protein 2 9 23690104-23826337 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022222, HPA063001 Supported Approved Nucleoplasm
Cytosol Group enriched 32 cerebral cortex: 38.1;testis: 80.2 adrenal gland: 1.8 -NCS1 FREQ, NCS-1 ENSG00000107130 Neuronal calcium sensor 1 9 130172578-130237304 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018587, HPA019713 Approved Validated Plasma membrane Tissue enhanced 0 cerebral cortex: 178.6 seminal vesicle: 91.2 -TESK1 ENSG00000107140 Testis-specific kinase 1 9 35605305-35610041 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 46.2 -KCNT1 KCa4.1, KIAA1422, SLACK, Slo2.2 ENSG00000107147 Potassium channel, sodium activated subfamily T, member 1 9 135702185-135795508 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059880 Uncertain Group enriched 5 cerebral cortex: 11.7;ovary: 3.9;skeletal muscle: 3.9;spleen: 6.7 testis: 1.2 -CA9 CAIX, MN ENSG00000107159 Carbonic anhydrase IX 9 35673856-35681159 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005100, CAB017107, HPA055207 Supported Validated Plasma membrane
Cytosol Tissue enhanced 0 gallbladder: 36.1;stomach: 92.4 small intestine: 14.8 -FUBP3 FBP3 ENSG00000107164 Far upstream element (FUSE) binding protein 3 9 130578965-130638352 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047658, HPA058392 Uncertain Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 71.5 -TYRP1 b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP ENSG00000107165 Tyrosinase-related protein 1 9 12685439-12710290 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000937, CAB002520 Supported Supported Vesicles Group enriched 6 heart muscle: 35.6;skin: 169.5 kidney: 16.9 -CREB3 Luman, LZIP, sLZIP ENSG00000107175 CAMP responsive element binding protein 3 9 35732320-35737007 Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA030978 Supported Cytosol Expressed in all prostate: 54.5 -RGP1 KIAA0258 ENSG00000107185 RGP1 homolog, RAB6A GEF complex partner 1 9 35749287-35758575 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020414, HPA021085 Approved Validated Plasma membrane
Cytosol Expressed in all parathyroid gland: 35.4 -MPDZ MUPP1 ENSG00000107186 Multiple PDZ domain protein 9 13105704-13279590 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013512, HPA020255, HPA026686 Uncertain Mixed liver: 44.3 -LHX3 ENSG00000107187 LIM homeobox 3 9 136196250-136205109 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Not detected cerebral cortex: 0.4 -DDX58 DKFZp434J1111, FLJ13599, RIG-I ENSG00000107201 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 9 32455705-32526324 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012643, HPA047193 Uncertain Supported Cytosol Expressed in all spleen: 20.2 -EDF1 CFAP280, EDF-1 ENSG00000107223 Endothelial differentiation-related factor 1 9 136862119-136866286 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035642 Approved Supported Nucleus
Cytosol Expressed in all small intestine: 569.2 -PIP5K1B MSS4, STM7 ENSG00000107242 Phosphatidylinositol-4-phosphate 5-kinase, type I, beta 9 68705414-69009176 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009687 Uncertain Approved Nucleus
Vesicles Mixed testis: 49.8 -GLIS3 MGC33662, ZNF515 ENSG00000107249 GLIS family zinc finger 3 9 3824127-4348392 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA056426 Approved Supported Nucleoplasm Tissue enhanced 0 thyroid gland: 34.8 fallopian tube: 17.0 -BAG1 ENSG00000107262 BCL2-associated athanogene 9 33247820-33264761 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002486, HPA018121 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 171.9 -RAPGEF1 C3G, GRF2 ENSG00000107263 Rap guanine nucleotide exchange factor (GEF) 1 9 131576770-131740074 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006426, HPA075984 Approved Supported Vesicles Expressed in all placenta: 80.2 -NPDC1 CAB-, CAB1, DKFZp586J0523 ENSG00000107281 Neural proliferation, differentiation and control, 1 9 137039470-137046203 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008189 Approved Approved Nucleus
Cytosol Expressed in all prostate: 108.1 -APBA1 D9S411E, MINT1, X11 ENSG00000107282 Amyloid beta (A4) precursor protein-binding, family A, member 1 9 69427530-69672306 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061287 Supported Golgi apparatus Tissue enhanced 0 cerebral cortex: 18.4 parathyroid gland: 11.6 -SETX ALS4, AOA2, KIAA0625, SCAR1 ENSG00000107290 Senataxin 9 132261356-132354985 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024105, HPA057269 Approved Supported Nucleus
Cytokinetic bridge Expressed in all testis: 58.1 -SH3GL2 CNSA2, EEN-B1, SH3D2A, SH3P4 ENSG00000107295 SH3-domain GRB2-like 2 9 17579082-17797129 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010056, HPA026685, HPA063573 Supported Supported Approved Microtubules
Cytokinetic bridge Tissue enriched 10 cerebral cortex: 170.6 kidney: 17.3 -PTGDS L-PGDS, PGDS ENSG00000107317 Prostaglandin D2 synthase 21kDa (brain) 9 136977505-136985435 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004938, CAB009916 Approved Expressed in all testis: 2586.0 -ABCA2 ABC2 ENSG00000107331 ATP-binding cassette, sub-family A (ABC1), member 2 9 137007227-137028922 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042886 Approved Tissue enriched 6 cerebral cortex: 98.2 thyroid gland: 17.0 -SHB ENSG00000107338 Src homology 2 domain containing adaptor protein B 9 37919134-38069211 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010161, HPA049911, HPA052108 Uncertain Validated Nucleoplasm
Cytosol
Cytoplasmic bodies Expressed in all parathyroid gland: 15.9 -UBE2R2 CDC34B, FLJ20419, MGC10481, UBC3B ENSG00000107341 Ubiquitin-conjugating enzyme E2R 2 9 33817567-33920404 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061000 Approved Nucleus
Nucleoli Expressed in all testis: 68.5 -ABHD17B C9orf77, CGI-67, FAM108B1 ENSG00000107362 Abhydrolase domain containing 17B 9 71862452-71910931 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047862 Uncertain Expressed in all cerebral cortex: 35.5 -EXOSC3 CGI-102, hRrp-40, hRrp40p, p10, RRP40, Rrp40p ENSG00000107371 Exosome component 3 9 37766978-37801437 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020485 Supported Supported Nucleoplasm Mixed testis: 28.0 -ZFAND5 ZA20D2, ZFAND5A, ZNF216 ENSG00000107372 Zinc finger, AN1-type domain 5 9 72351425-72365235 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018129 Approved Approved Nucleoplasm
Cytosol Expressed in all adipose tissue: 309.5 -DVL1 ENSG00000107404 Dishevelled segment polarity protein 1 1 1335276-1349350 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011538 Approved Expressed in all skeletal muscle: 79.5 -PDLIM1 CLIM1, CLP-36, CLP36, hCLIM1 ENSG00000107438 PDZ and LIM domain 1 10 95237572-95291024 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017010, CAB072838, CAB072840 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Expressed in all small intestine: 278.6 -CCNJ bA690P14.1, FLJ10895 ENSG00000107443 Cyclin J 10 96043394-96060870 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036531, HPA058151 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 9.8 -DNTT TDT ENSG00000107447 DNA nucleotidylexotransferase 10 96304396-96338564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044194 Approved Nucleoplasm
Cytosol Tissue enriched 8 bone marrow: 18.4 tonsil: 2.2 -GATA3 HDR ENSG00000107485 GATA binding protein 3 10 8053604-8075198 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016217, HPA029730, HPA029731 Supported Supported Nucleoplasm Tissue enhanced 0 parathyroid gland: 231.0;skin: 149.3 placenta: 44.1 -ATRNL1 ALP, FLJ45344, KIAA0534 ENSG00000107518 Attractin-like 1 10 115093365-115948992 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038070 Uncertain Approved Nucleus
Mitochondria Tissue enhanced 0 cerebral cortex: 34.0 testis: 22.6 -HPS1 BLOC3S1, HPS ENSG00000107521 Hermansky-Pudlak syndrome 1 10 98416198-98446947 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061260 Approved Expressed in all lymph node: 24.6 -PHYH PAHX, PHYH1, RD ENSG00000107537 Phytanoyl-CoA 2-hydroxylase 10 13277796-13302412 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007598, HPA011796 Approved Expressed in all liver: 333.3 -RASSF4 AD037, MGC44914 ENSG00000107551 Ras association (RalGDS/AF-6) domain family member 4 10 44959407-44995891 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038834 Approved Approved Nucleus
Nucleoli
Cell Junctions Expressed in all cerebral cortex: 71.6 -DNMBP ARHGEF36, KIAA1010, Tuba ENSG00000107554 Dynamin binding protein 10 99875577-100009919 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037878, HPA058216 Uncertain Approved Nucleoli
Nuclear bodies
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 56.8 -RAB11FIP2 KIAA0941, nRip11, Rab11-FIP2 ENSG00000107560 RAB11 family interacting protein 2 (class I) 10 118004916-118046603 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037726 Approved Supported Nucleoplasm
Vesicles Expressed in all seminal vesicle: 36.2 -CXCL12 PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1 ENSG00000107562 Chemokine (C-X-C motif) ligand 12 10 44370165-44386493 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017564 Approved Expressed in all endometrium: 615.4 -ERLIN1 C10orf69, Erlin-1, KE04, SPFH1, SPG62 ENSG00000107566 ER lipid raft associated 1 10 100150094-100188334 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011252 Approved Supported Endoplasmic reticulum Expressed in all placenta: 56.8 -EIF3A EIF3, eIF3-p170, eIF3-theta, eIF3a, EIF3S10, KIAA0139, TIF32 ENSG00000107581 Eukaryotic translation initiation factor 3, subunit A 10 119033670-119080823 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038315, HPA038316 Supported Supported Nucleus
Cytosol Expressed in all parathyroid gland: 134.6 -PKD2L1 PCL, PKD2L, PKDL, TRPP3 ENSG00000107593 Polycystic kidney disease 2-like 1 10 100288154-100330486 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022621 Uncertain Tissue enhanced 0 spleen: 10.0 lung: 3.4 -CUBN gp280, IFCR, MGA1 ENSG00000107611 Cubilin (intrinsic factor-cobalamin receptor) 10 16823964-17129831 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 22 kidney: 152.5;small intestine: 55.3 thyroid gland: 4.7 -TRDMT1 DNMT2, RNMT1 ENSG00000107614 TRNA aspartic acid methyltransferase 1 10 17142254-17202054 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009468, HPA036945, HPA036946 Approved Approved Nucleus
Nucleoli
Centrosome Mixed parathyroid gland: 8.5 -DDX50 GU2, GUB, MGC3199, RH-II/GuB ENSG00000107625 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 10 68901278-68946847 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037388, HPA037389, HPA058196 Approved Validated Nucleoli Expressed in all testis: 46.9 -MAPK8 JNK, JNK1, PRKM8, SAPK1 ENSG00000107643 Mitogen-activated protein kinase 8 10 48306639-48439360 Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004463, CAB069396 Approved Expressed in all testis: 34.9 -SEC23IP p125 ENSG00000107651 SEC23 interacting protein 10 119892711-119944658 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038403, HPA043305 Approved Validated Vesicles Expressed in all smooth muscle: 30.1 -ATE1 ENSG00000107669 Arginyltransferase 1 10 121740421-121928801 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038444, HPA057549 Approved Supported Nucleus Expressed in all thyroid gland: 31.2 -NSMCE4A bA500G22.3, C10orf86, FLJ20003, NSE4A ENSG00000107672 NSE4 homolog A, SMC5-SMC6 complex component 10 121957088-121975217 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037459, HPA038412, HPA044872 Approved Validated Nucleoplasm Expressed in all prostate: 35.0 -PLEKHA1 TAPP1 ENSG00000107679 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 10 122374696-122442602 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002043, HPA064795 Approved Validated Nucleus
Cytosol Expressed in all skin: 79.5 -PALD1 KIAA1274, PALD ENSG00000107719 Phosphatase domain containing, paladin 1 10 70478821-70568449 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015696, HPA017343 Uncertain Mixed lung: 15.0 -UNC5B p53RDL1, UNC5H2 ENSG00000107731 Unc-5 netrin receptor B 10 71212570-71302864 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 seminal vesicle: 38.1 cerebral cortex: 16.9 -CDH23 CDHR23, DFNB12, USH1D ENSG00000107736 Cadherin-related 23 10 71396934-71815947 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA017232 Approved Tissue enhanced 0 parathyroid gland: 29.7 ovary: 19.4 -C10orf54 B7-H5, B7H5, GI24, SISP1, VISTA ENSG00000107738 Chromosome 10 open reading frame 54 10 71747559-71773498 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007968 Uncertain Approved Nucleoplasm Expressed in all spleen: 188.4 -SPOCK2 KIAA0275, testican-2 ENSG00000107742 Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 10 72059035-72089032 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044605 Supported Uncertain Nuclear speckles Tissue enhanced 0 cerebral cortex: 162.2;lung: 128.2 lymph node: 76.0 -MICU1 CALC, CBARA1, EFHA3, FLJ12684 ENSG00000107745 Mitochondrial calcium uptake 1 10 72367327-72626191 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037479, HPA037480 Uncertain Supported Mitochondria Expressed in all kidney: 107.0 -PPP3CB CALNA2, CALNB, CNA2, PP2Bbeta ENSG00000107758 Protein phosphatase 3, catalytic subunit, beta isozyme 10 73436428-73496024 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008233, HPA008823 Uncertain Approved Mitochondria Expressed in all cerebral cortex: 153.6 -CCSER2 FAM190B, KIAA1128 ENSG00000107771 Coiled-coil serine-rich protein 2 10 84328586-84518521 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037481, HPA037482 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 39.6 -BMPR1A ACVRLK3, ALK3, CD292 ENSG00000107779 Bone morphogenetic protein receptor, type IA 10 86756650-86932838 Cancer-related genes, CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB019398 Approved Approved Cytosol Mixed thyroid gland: 33.8 -MINPP1 MIPP ENSG00000107789 Multiple inositol-polyphosphate phosphatase 1 10 87504875-87553460 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026859 Approved Expressed in all placenta: 27.3 -ACTA2 ACTSA ENSG00000107796 Actin, alpha 2, smooth muscle, aorta 10 88935074-88991390 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000002, CAB013531, HPA041264, HPA041271 Supported Expressed in all smooth muscle: 11586.2 -LIPA CESD, LAL ENSG00000107798 Lipase A, lysosomal acid, cholesterol esterase 10 89213569-89414557 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034892, HPA057052 Supported Supported Vesicles Expressed in all spleen: 503.4 -TLX1 HOX11, TCL3 ENSG00000107807 T-cell leukemia homeobox 1 10 101130505-101137789 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 5 spleen: 32.5 salivary gland: 6.1 -C10orf2 FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL ENSG00000107815 Chromosome 10 open reading frame 2 10 100987367-100994401 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002532 Uncertain Expressed in all testis: 13.6 -LZTS2 KIAA1813, LAPSER1 ENSG00000107816 Leucine zipper, putative tumor suppressor 2 10 100996618-101007836 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044956 Approved Approved Plasma membrane
Cytosol Expressed in all endometrium: 57.8 -SFXN3 SFX3 ENSG00000107819 Sideroflexin 3 10 101031234-101041244 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008028, HPA048105 Approved Validated Mitochondria Expressed in all small intestine: 42.2 -KAZALD1 FKSG28, FKSG40 ENSG00000107821 Kazal-type serine peptidase inhibitor domain 1 10 101061841-101068131 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011800 Uncertain Tissue enhanced 0 spleen: 27.3 cervix: 15.6 -FBXW4 dactylin, Fbw4, SHFM3 ENSG00000107829 F-box and WD repeat domain containing 4 10 101610664-101695295 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043496 Approved Approved Golgi apparatus Expressed in all parathyroid gland: 79.6 -FGF8 AIGF ENSG00000107831 Fibroblast growth factor 8 (androgen-induced) 10 101770130-101780369 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 6 skeletal muscle: 15.7 testis: 2.5 -NPM3 ENSG00000107833 Nucleophosmin/nucleoplasmin 3 10 101781325-101783413 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036295, HPA036296 Approved Approved Nucleoli
Actin filaments
Cytosol Expressed in all smooth muscle: 28.4 -TNKS2 PARP-5b, PARP-5c, PARP5B, PARP5C, pART6, TANK2, TNKL ENSG00000107854 Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 10 91798312-91865276 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036606 Approved Microtubules Expressed in all thyroid gland: 50.1 -PITX3 ASMD ENSG00000107859 Paired-like homeodomain 3 10 102230186-102241474 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 10 adipose tissue: 1.2;skeletal muscle: 5.6 testis: 0.3 -GBF1 ARF1GEF, KIAA0248 ENSG00000107862 Golgi brefeldin A resistant guanine nucleotide exchange factor 1 10 102245532-102382899 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037759, HPA037760 Uncertain Supported Golgi apparatus Expressed in all parathyroid gland: 58.1 -ARHGAP21 ARHGAP10, KIAA1424 ENSG00000107863 Rho GTPase activating protein 21 10 24583609-24723668 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036610, HPA057861 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Expressed in all cerebral cortex: 103.8 -CPEB3 KIAA0940 ENSG00000107864 Cytoplasmic polyadenylation element binding protein 3 10 92046692-92291087 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059056 Approved Nucleoplasm
Nuclear bodies
Intermediate filaments Mixed cerebral cortex: 16.1 -FBXL15 Fbl15, FBXO37, MGC11279 ENSG00000107872 F-box and leucine-rich repeat protein 15 10 102419189-102423136 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 13.5 -CUEDC2 C10orf66, MGC2491 ENSG00000107874 CUE domain containing 2 10 102423245-102432661 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036544, HPA041829 Uncertain Validated Nucleoplasm
Cytosol Expressed in all cerebral cortex: 90.2 -SUFU PRO1280, SUFUH, SUFUXL ENSG00000107882 Suppressor of fused homolog (Drosophila) 10 102503987-102633535 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008700 Supported Supported Nucleus Mixed parathyroid gland: 15.8 -ANKRD26 KIAA1074, THC2 ENSG00000107890 Ankyrin repeat domain 26 10 26991914-27100498 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040654, HPA041460 Approved Approved Golgi apparatus
Vesicles Mixed testis: 10.8 -ACBD5 DKFZp434A2417, KIAA1996 ENSG00000107897 Acyl-CoA binding domain containing 5 10 27195214-27242130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011861, HPA012145 Supported Validated Peroxisomes Expressed in all cerebral cortex: 57.3 -LHPP HDHD2B ENSG00000107902 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase 10 124461834-124617888 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009163, HPA009269 Supported Supported Nuclear speckles
Cytosol Expressed in all cerebral cortex: 70.8 -LARP4B KIAA0217, LARP5 ENSG00000107929 La ribonucleoprotein domain family, member 4B 10 806914-931705 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036566, HPA042738 Approved Validated Cytosol Expressed in all thyroid gland: 38.0 -GTPBP4 CRFG, FLJ10686, FLJ10690, NGB, NOG1 ENSG00000107937 GTP binding protein 4 10 988019-1019936 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039618, HPA056468 Uncertain Validated Nuclear membrane
Nucleoli Expressed in all testis: 37.2 -EDRF1 C10orf137, DKFZp586F1019, FLJ21617 ENSG00000107938 Erythroid differentiation regulatory factor 1 10 125719515-125764143 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031820 Approved Nucleoplasm
Centrosome
Cytosol Expressed in all testis: 27.5 -BCCIP BCCIPalpha, TOK-1 ENSG00000107949 BRCA2 and CDKN1A interacting protein 10 125823546-125853695 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038011 Supported Nucleoplasm
Cytosol Expressed in all testis: 89.2 -MTPAP FLJ10486, mtPAP, PAPD1, SPAX4 ENSG00000107951 Mitochondrial poly(A) polymerase 10 30309801-30374448 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038620, HPA058232 Approved Supported Mitochondria Expressed in all bone marrow: 22.7 -NEURL1 h-neu, neu-1, NEURL, RNF67 ENSG00000107954 Neuralized E3 ubiquitin protein ligase 1 10 103493979-103592552 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044204 Uncertain Tissue enhanced 0 skeletal muscle: 50.9 cerebral cortex: 30.2 -SH3PXD2A FISH, KIAA0418, SH3MD1 ENSG00000107957 SH3 and PX domains 2A 10 103594027-103855543 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037922, HPA037923 Approved Mixed cervix: 63.4 -PITRM1 hMP1, KIAA1104, MP1, PreP ENSG00000107959 Pitrilysin metallopeptidase 1 10 3137728-3172841 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006753, HPA006754 Supported Supported Mitochondria Expressed in all testis: 87.9 -OBFC1 bA541N10.2, FLJ22559 ENSG00000107960 Oligonucleotide/oligosaccharide-binding fold containing 1 10 103882542-103918205 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037924, HPA037925 Supported Nucleus Expressed in all parathyroid gland: 48.8 -MAP3K8 c-COT, COT, EST, ESTF, MEKK8, Tpl-2 ENSG00000107968 Mitogen-activated protein kinase kinase kinase 8 10 30433937-30461833 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005120, HPA017962 Supported Supported Cytosol Expressed in all bone marrow: 210.1 -DKK1 DKK-1, SK ENSG00000107984 Dickkopf WNT signaling pathway inhibitor 1 10 52314296-52318042 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cervix, uterine: 56.3;placenta: 71.5 urinary bladder: 14.9 -EBF3 COE3, DKFZp667B0210 ENSG00000108001 Early B-cell factor 3 10 129835283-129963841 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA061169 Approved Nucleoplasm
Vesicles Tissue enhanced 0 adipose tissue: 20.1 lymph node: 12.9 -GLRX3 bA500G10.4, GLRX4, GRX3, GRX4, PICOT, TXNL2 ENSG00000108010 Glutaredoxin 3 10 130136399-130184521 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028941 Approved Expressed in all testis: 118.7 -SORCS1 sorCS1 ENSG00000108018 Sortilin-related VPS10 domain containing receptor 1 10 106573663-107164534 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011948 Approved Approved Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 12.2;thyroid gland: 18.0 kidney: 4.8 -FAM208B bA318E3.2, C10orf18, FLJ20360, KIAA2006 ENSG00000108021 Family with sequence similarity 208, member B 10 5684838-5763740 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038042, HPA038043, HPA061547 Uncertain Supported Nucleus
Cytosol Expressed in all testis: 43.8 -XPNPEP1 XPNPEP, XPNPEPL, XPNPEPL1 ENSG00000108039 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 10 109864766-109923553 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025196, HPA030419, HPA030420, HPA030422 Supported Validated Cytosol Expressed in all small intestine: 67.5 -SMC3 BAM, bamacan, CSPG6, HCAP, SMC3L1 ENSG00000108055 Structural maintenance of chromosomes 3 10 110567691-110604636 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037411, HPA043206 Uncertain Supported Nucleoplasm Expressed in all testis: 94.5 -SHOC2 KIAA0862, SOC-2, SOC2, SUR-8, SUR8 ENSG00000108061 SHOC2 leucine-rich repeat scaffold protein 10 110919547-111013667 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009164 Uncertain Approved Nucleoplasm
Cytosol Expressed in all testis: 65.0 -TFAM TCF6, TCF6L2 ENSG00000108064 Transcription factor A, mitochondrial 10 58385022-58399221 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040648, HPA063684 Supported Validated Mitochondria Expressed in all testis: 62.0 -CCDC6 D10S170, H4, PTC, TPC, TST1 ENSG00000108091 Coiled-coil domain containing 6 10 59788763-59906656 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019049, HPA019051 Supported Supported Cytosol Expressed in all smooth muscle: 43.8 -CUL2 ENSG00000108094 Cullin 2 10 35008551-35090642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002677, HPA024578 Approved Validated Nucleoplasm Expressed in all testis: 64.8 -CCNY C10orf9, CBCP1, CFP1 ENSG00000108100 Cyclin Y 10 35247025-35572669 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036290 Approved Expressed in all testis: 149.6 -UBE2S E2-EPF ENSG00000108106 Ubiquitin-conjugating enzyme E2S 19 55399745-55407777 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015228, HPA057150 Approved Approved Nucleoplasm
Plasma membrane Expressed in all testis: 120.1 -RPL28 FLJ43307, L28 ENSG00000108107 Ribosomal protein L28 19 55385345-55403250 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050459 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all lymph node: 2004.1 -ZMIZ1 FLJ13541, hZIMP10, KIAA1224, MIZ, RAI17, RP11-519K18.1, Zimp10 ENSG00000108175 Zinc finger, MIZ-type containing 1 10 79069035-79316528 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045144 Approved Approved Nucleoplasm
Vesicles Expressed in all cerebral cortex: 65.5 -DNAJC12 JDP1 ENSG00000108176 DnaJ (Hsp40) homolog, subfamily C, member 12 10 67796665-67838166 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036289, HPA058161 Approved Approved Nucleus
Cytosol Tissue enhanced 0 adrenal gland: 58.0 breast: 38.7 -PPIF Cyp-D, hCyP3 ENSG00000108179 Peptidylprolyl isomerase F 10 79347469-79355337 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA077416 Supported Mitochondria Expressed in all adrenal gland: 189.4 -PBLD FLJ14767, MAWBP, MAWDBP ENSG00000108187 Phenazine biosynthesis-like protein domain containing 10 68282660-68333049 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038035, HPA038036 Supported Approved Vesicles Expressed in all kidney: 276.9 -TSPAN14 DC-TM4F2, MGC11352, TM4SF14 ENSG00000108219 Tetraspanin 14 10 80454166-80533123 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014773, HPA057174 Uncertain Supported Vesicles Expressed in all placenta: 128.3 -LGI1 EPITEMPIN, EPT, ETL1, IB1099 ENSG00000108231 Leucine-rich, glioma inactivated 1 10 93757809-93798174 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 11 cerebral cortex: 51.3 esophagus: 4.7 -TBC1D12 KIAA0608 ENSG00000108239 TBC1 domain family, member 12 10 94402504-94535930 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038277, HPA038645 Uncertain Approved Nucleoplasm
Nuclear speckles Mixed parathyroid gland: 19.1 -CYP2C18 CPCI, CYP2C, CYP2C17, P450IIC17 ENSG00000108242 Cytochrome P450, family 2, subfamily C, polypeptide 18 10 94683621-94736190 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 10 duodenum: 105.9;esophagus: 24.7;gallbladder: 24.5;liver: 97.7;small intestine: 90.0;stomach: 62.7 tonsil: 6.4 -KRT23 CK23, DKFZP434G032, HAIK1, K23, MGC26158 ENSG00000108244 Keratin 23, type I 17 40922696-40937634 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012050, HPA016959, CAB017091 Approved Approved Intermediate filaments
Cytosol Tissue enhanced 0 placenta: 68.3;skin: 71.0 salivary gland: 41.5 -CRYBA1 CRYB1 ENSG00000108255 Crystallin, beta A1 17 29246863-29254494 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Not detected parathyroid gland: 0.2 -NUFIP2 182-FIP, 82-FIP, FIP-82, KIAA1321, MGC117262, PIG1 ENSG00000108256 Nuclear fragile X mental retardation protein interacting protein 2 17 29255836-29294118 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067443 Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all bone marrow: 53.4 -GIT1 ENSG00000108262 G protein-coupled receptor kinase interacting ArfGAP 1 17 29573469-29594054 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004059, HPA004186 Approved Validated Focal adhesion sites
Cytosol Expressed in all testis: 127.5 -RPL19 DKFZp779D216, FLJ27452, L19, MGC71997 ENSG00000108298 Ribosomal protein L19 17 39200283-39204727 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043014, HPA051987 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 4342.3 -FBXL20 Fbl2, Fbl20, MGC15482 ENSG00000108306 F-box and leucine-rich repeat protein 20 17 39252644-39402523 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044748, HPA050397 Uncertain Supported Microtubules Mixed testis: 22.9 -RUNDC3A RAP2IP, RPIP8 ENSG00000108309 RUN domain containing 3A 17 44308413-44318671 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023548 Uncertain Approved Vesicles Tissue enriched 9 cerebral cortex: 191.3 adrenal gland: 21.4 -UBTF NOR-90, UBF, UBF1, UBF2 ENSG00000108312 Upstream binding transcription factor, RNA polymerase I 17 44205033-44221626 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004611, HPA006385 Supported Supported Validated Nucleoli fibrillar center Expressed in all lymph node: 82.3 -CSF3 C17orf33, G-CSF, GCSF, MGC45931 ENSG00000108342 Colony stimulating factor 3 (granulocyte) 17 40015361-40017813 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001412, CAB016131 Approved Tissue enhanced 0 appendix: 19.4;cervix, uterine: 38.0 adipose tissue: 10.2 -PSMD3 P58, Rpn3, S3, TSTA2 ENSG00000108344 Proteasome 26S subunit, non-ATPase 3 17 39980797-39997960 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017038, HPA048972 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 83.8 -CASC3 BTZ, MLN51 ENSG00000108349 Cancer susceptibility candidate 3 17 40140318-40172183 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024592, HPA050262 Approved Approved Nuclear membrane Expressed in all testis: 94.9 -RAPGEFL1 Link-GEFII ENSG00000108352 Rap guanine nucleotide exchange factor (GEF)-like 1 17 40177010-40195656 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022895 Approved Nucleus
Microtubules
Cytokinetic bridge Tissue enhanced 0 skin: 277.6 esophagus: 93.6 -RGS9 MGC111763, MGC26458, PERRS, RGS9L ENSG00000108370 Regulator of G-protein signaling 9 17 65137431-65227703 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013550, HPA014137 Supported Supported Uncertain Nucleoplasm Mixed fallopian tube: 5.8 -RNF43 DKFZp781H0392, FLJ20315, URCC ENSG00000108375 Ring finger protein 43 17 58352500-58417595 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA008079 Uncertain Mixed duodenum: 24.1 -WNT3 INT4, MGC131950, MGC138321, MGC138323 ENSG00000108379 Wingless-type MMTV integration site family, member 3 17 46762506-46833154 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA066281 Approved Vesicles Group enriched 5 duodenum: 2.3;parathyroid gland: 2.3;skin: 9.2 cerebral cortex: 0.9 -ASPA ACY2, ASP ENSG00000108381 Aspartoacylase 17 3472374-3503419 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022142, HPA022145 Approved Uncertain Cytosol Tissue enhanced 0 kidney: 39.5 cerebral cortex: 24.8 -RAD51C FANCO, RAD51L2 ENSG00000108384 RAD51 paralog C 17 58692573-58735611 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045198 Supported Nucleus
Vesicles
Cell Junctions
Mitochondria
Cytosol Expressed in all testis: 37.1 -SEPT4 ARTS, CE5B3, H5, hCDCREL-2, hucep-7, MART, PNUTL2 ENSG00000108387 Septin 4 17 58520250-58540818 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006855, HPA021587, HPA022905 Supported Supported Nucleoplasm Group enriched 5 adrenal gland: 218.2;cerebral cortex: 288.7;spleen: 57.8 adipose tissue: 36.8 -MTMR4 KIAA0647, ZFYVE11 ENSG00000108389 Myotubularin related protein 4 17 58489529-58517905 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 35.5 -TRIM37 KIAA0898, MUL, POB1, TEF3 ENSG00000108395 Tripartite motif containing 37 17 58982638-59106921 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021911 Uncertain Expressed in all testis: 117.1 -P2RX1 P2X1 ENSG00000108405 Purinergic receptor P2X, ligand gated ion channel, 1 17 3896592-3916500 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 seminal vesicle: 45.7;urinary bladder: 43.2 bone marrow: 26.3 -DHX40 ARG147, DDX40, FLJ22060, PAD ENSG00000108406 DEAH (Asp-Glu-Ala-His) box polypeptide 40 17 59565525-59608345 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044350 Uncertain Supported Nucleus Expressed in all parathyroid gland: 88.1 -KRT37 KRTHA7 ENSG00000108417 Keratin 37, type I 17 41420753-41424523 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 skin: 1.2 cervix: 0.3 -TUBD1 FLJ12709, TUBD ENSG00000108423 Tubulin, delta 1 17 59859482-59892945 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB004609, HPA023980, HPA027090 Approved Validated Nucleoplasm
Cytosol Expressed in all thyroid gland: 12.7 -KPNB1 IMB1, Impnb, IPO1, IPOB, MGC2155, MGC2156, MGC2157, NTF97 ENSG00000108424 Karyopherin (importin) beta 1 17 47649476-47685505 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029878, CAB034449, HPA050302 Supported Supported Nucleoplasm
Nuclear membrane
Cytosol Expressed in all testis: 218.3 -GOSR2 Bos1, GS27 ENSG00000108433 Golgi SNAP receptor complex member 2 17 46923117-46967019 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017456, HPA048956, HPA054472 Uncertain Supported Nucleoplasm
Golgi apparatus Expressed in all testis: 132.2 -PNPO PDXPO ENSG00000108439 Pyridoxamine 5'-phosphate oxidase 17 47941506-47948288 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023204, HPA027776 Approved Supported Nucleoplasm
Cytosol Expressed in all liver: 51.2 -RPS6KB1 p70(S6K)-alpha, PS6K, S6K1, STK14A ENSG00000108443 Ribosomal protein S6 kinase, 70kDa, polypeptide 1 17 59893046-59950564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003838, CAB018346, HPA039442 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 28.0 -TRIM16L TRIM70 ENSG00000108448 Tripartite motif containing 16-like 17 18697998-18736118 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA066431 Approved Plasma membrane
Cytosol Mixed gallbladder: 22.7 -CDK5RAP3 C53, FLJ13660, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114 ENSG00000108465 CDK5 regulatory subunit associated protein 3 17 47967810-47981774 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022141, HPA022882, HPA027883 Supported Supported Cytosol Expressed in all epididymis: 107.9 -CBX1 CBX, HP1-BETA, HP1Hs-beta, M31, MOD1 ENSG00000108468 Chromobox homolog 1 17 48070052-48101521 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012265 Supported Supported Nucleus
Nuclear bodies Expressed in all testis: 125.1 -RECQL5 FLJ90603, RecQ5 ENSG00000108469 RecQ helicase-like 5 17 75626845-75667189 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029970, HPA029971 Uncertain Supported Nucleus
Cytosol Expressed in all thyroid gland: 27.6 -PIGL ENSG00000108474 Phosphatidylinositol glycan anchor biosynthesis, class L 17 16217191-16351797 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012739 Approved Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 14.6 -GALK1 GALK ENSG00000108479 Galactokinase 1 17 75751594-75765711 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007094, HPA016960 Approved Approved Golgi apparatus
Cytosol Expressed in all duodenum: 23.8 -INTS2 INT2, KIAA1287 ENSG00000108506 Integrator complex subunit 2 17 61865367-61928016 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049524 Uncertain Approved Nucleoplasm Mixed testis: 11.4 -CAMTA2 KIAA0909 ENSG00000108509 Calmodulin binding transcription activator 2 17 4967992-4987652 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051147 Approved Nucleus
Actin filaments
Mitochondria Expressed in all cerebral cortex: 40.6 -MED13 KIAA0593, THRAP1, TRAP240 ENSG00000108510 Mediator complex subunit 13 17 61942605-62065282 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067939 Supported Nucleus Expressed in all testis: 35.5 -HOXB6 HOX2, HOX2B ENSG00000108511 Homeobox B6 17 48595751-48604992 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042063 Approved Nucleus
Golgi apparatus Tissue enhanced 0 epididymis: 48.4;seminal vesicle: 29.8 cervix: 26.3 -ENO3 ENSG00000108515 Enolase 3 (beta, muscle) 17 4948092-4957131 Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000793, HPA068284 Approved Validated Plasma membrane
Cytosol Tissue enriched 19 skeletal muscle: 5975.8 heart muscle: 311.9 -PFN1 ENSG00000108518 Profilin 1 17 4945652-4949061 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037134, CAB037140 Supported Supported Cytosol Expressed in all appendix: 919.1 -RNF167 DKFZP566H073 ENSG00000108523 Ring finger protein 167 17 4940008-4945222 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049810 Approved Approved Cytosol Expressed in all parathyroid gland: 114.7 -SLC25A11 OGC, SLC20A4 ENSG00000108528 Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 17 4937130-4940251 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021167 Approved Expressed in all heart muscle: 148.2 -RASD1 AGS1, DEXRAS1 ENSG00000108551 RAS, dexamethasone-induced 1 17 17494437-17496395 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047896 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all adipose tissue: 112.9 -CHRNE ACHRE ENSG00000108556 Cholinergic receptor, nicotinic, epsilon (muscle) 17 4897774-4903074 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 27 heart muscle: 34.4 epididymis: 1.2 -RAI1 DKFZP434A139, KIAA1820, MGC12824, SMCR, SMS ENSG00000108557 Retinoic acid induced 1 17 17681473-17811453 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023898, HPA054906 Validated Nucleoplasm Expressed in all parathyroid gland: 19.3 -NUP88 MGC8530 ENSG00000108559 Nucleoporin 88kDa 17 5360963-5420160 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002209, HPA021816 Approved Supported Nucleoplasm Expressed in all testis: 94.1 -C1QBP gC1Q-R, gC1qR, HABP1, p32, SF2p32 ENSG00000108561 Complement component 1, q subcomponent binding protein 17 5432777-5448830 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026483 Supported Approved Plasma membrane
Mitochondria Expressed in all rectum: 159.4 -SLC6A4 5-HTT, HTT, OCD1, SERT1 ENSG00000108576 Solute carrier family 6 (neurotransmitter transporter), member 4 17 30194319-30236002 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054723, HPA074728 Supported Supported Golgi apparatus
Vesicles Group enriched 10 duodenum: 10.7;lung: 44.2;placenta: 26.3;small intestine: 46.2 esophagus: 3.1 -BLMH BH ENSG00000108578 Bleomycin hydrolase 17 30248195-30292056 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039548, HPA064307 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all skin: 140.2 -CPD GP180 ENSG00000108582 Carboxypeptidase D 17 30378905-30469989 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052796, HPA055465 Approved Approved Nucleoplasm
Nuclear membrane
Nuclear speckles Expressed in all thyroid gland: 94.6 -GOSR1 GOLIM2, GOS-28, GOS28, GS28, P28 ENSG00000108587 Golgi SNAP receptor complex member 1 17 30477362-30527592 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020590 Uncertain Expressed in all parathyroid gland: 54.8 -CCDC47 GK001 ENSG00000108588 Coiled-coil domain containing 47 17 63745250-63776351 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029674, HPA072573 Approved Validated Endoplasmic reticulum Expressed in all parathyroid gland: 159.7 -MED31 CGI-125, Soh1 ENSG00000108590 Mediator complex subunit 31 17 6643315-6651634 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035947 Uncertain Approved Nucleus Expressed in all testis: 31.0 -DRG2 ENSG00000108591 Developmentally regulated GTP binding protein 2 17 18087886-18107971 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007716 Approved Supported Nucleoplasm
Vesicles
Cytosol Expressed in all fallopian tube: 29.0 -FTSJ3 SPB1 ENSG00000108592 FtsJ homolog 3 (E. coli) 17 63819433-63830012 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055544, HPA062628 Supported Validated Nucleoli Expressed in all parathyroid gland: 49.4 -AKAP10 D-AKAP2, MGC9414, PRKA10 ENSG00000108599 A kinase (PRKA) anchor protein 10 17 19904302-19978343 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028901 Approved Supported Plasma membrane
Cytosol Expressed in all testis: 26.1 -ALDH3A1 ALDH3 ENSG00000108602 Aldehyde dehydrogenase 3 family, member A1 17 19737984-19748943 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045957, HPA051150, HPA063783 Supported Validated Vesicles
Plasma membrane
Cytosol Group enriched 7 esophagus: 407.6;skin: 84.5;stomach: 210.9 tonsil: 32.2 -SMARCD2 BAF60B, CRACD2, PRO2451, Rsc6p ENSG00000108604 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 17 63832081-63843065 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059934, HPA061348 Validated Nucleoplasm Expressed in all skin: 104.9 -ICAM2 CD102 ENSG00000108622 Intercellular adhesion molecule 2 17 64002594-64020634 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071155 Uncertain Cytosol Expressed in all spleen: 203.8 -SYNGR2 ENSG00000108639 Synaptogyrin 2 17 78168558-78173527 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014742 Approved Approved Golgi apparatus Expressed in all lung: 155.0 -B9D1 B9, EPPB9, MKS9 ENSG00000108641 B9 protein domain 1 17 19337554-19378182 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA022957 Approved Expressed in all fallopian tube: 101.0 -UTP6 C17orf40, HCA66 ENSG00000108651 UTP6, small subunit (SSU) processome component, homolog (yeast) 17 31860899-31901765 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA025936, HPA055806 Supported Validated Nucleoli Expressed in all epididymis: 15.3 -DDX5 G17P1, HLR1, p68 ENSG00000108654 DEAD (Asp-Glu-Ala-Asp) box helicase 5 17 64499616-64508199 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005868, HPA020043 Supported Validated Nucleoplasm Expressed in all smooth muscle: 594.4 -C17orf75 NJMU-R1 ENSG00000108666 Chromosome 17 open reading frame 75 17 32324565-32350023 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004061 Approved Approved Approved Golgi apparatus
Cytosol Expressed in all testis: 39.5 -CYTH1 B2-1, cytohesin-1, D17S811E, PSCD1 ENSG00000108669 Cytohesin 1 17 78674048-78782297 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047498 Uncertain Nucleus
Nucleoli Expressed in all lymph node: 93.7 -PSMD11 MGC3844, p44.5, Rpn6, S9 ENSG00000108671 Proteasome 26S subunit, non-ATPase 11 17 32444261-32483318 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042275, HPA067433 Approved Approved Nucleus
Golgi apparatus Expressed in all parathyroid gland: 61.7 -LGALS3BP 90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B ENSG00000108679 Lectin, galactoside-binding, soluble, 3 binding protein 17 78971238-78980109 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000554, CAB002158 Supported Expressed in all gallbladder: 324.9 -ASIC2 ACCN, ACCN1, ASIC2a, BNaC1, BNC1, hBNaC1, MDEG ENSG00000108684 Acid sensing (proton gated) ion channel 2 17 33013087-34174964 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052112 Approved Group enriched 6 cerebral cortex: 8.7;cervix, uterine: 3.9;endometrium: 6.4;smooth muscle: 2.1 adrenal gland: 0.8 -CCL7 FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7 ENSG00000108688 Chemokine (C-C motif) ligand 7 17 34270221-34272242 Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 8 appendix: 3.6;bone marrow: 15.3 gallbladder: 1.1 -CCL2 GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF ENSG00000108691 Chemokine (C-C motif) ligand 2 17 34255218-34257203 Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013676, HPA019163 Approved Approved Golgi apparatus
Vesicles Expressed in all gallbladder: 412.4 -CCL8 HC14, MCP-2, SCYA8 ENSG00000108700 Chemokine (C-C motif) ligand 8 17 34319036-34321402 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed adipose tissue: 13.0 -CCL1 I-309, P500, SCYA1, SISe, TCA3 ENSG00000108702 Chemokine (C-C motif) ligand 1 17 34360328-34363231 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049861 Uncertain Tissue enriched 5 rectum: 2.7 testis: 0.4 -PEX12 ENSG00000108733 Peroxisomal biogenesis factor 12 17 35574795-35578863 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069386 Supported Mixed parathyroid gland: 17.0 -KRT32 Ha-2, KRTHA2 ENSG00000108759 Keratin 32, type I 17 41459811-41467429 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 13 esophagus: 7.5;skin: 2.4 breast: 0.3 -DHX58 D11LGP2, LGP2 ENSG00000108771 DEXH (Asp-Glu-X-His) box polypeptide 58 17 42101404-42112733 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018670, HPA019570 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all spleen: 25.3 -KAT2A GCN5, GCN5L2, PCAF-b ENSG00000108773 K(lysine) acetyltransferase 2A 17 42113108-42121358 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048958 Uncertain Expressed in all skin: 10.9 -RAB5C RAB5CL, RABL ENSG00000108774 RAB5C, member RAS oncogene family 17 42124976-42155044 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003426, HPA004167 Approved Validated Endosomes Expressed in all thyroid gland: 179.8 -NAGLU NAG ENSG00000108784 N-acetylglucosaminidase, alpha 17 42536172-42544449 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038815 Supported Approved Expressed in all thyroid gland: 47.4 -HSD17B1 EDH17B2, EDHB17, HSD17, MGC138140, SDR28C1 ENSG00000108786 Hydroxysteroid (17-beta) dehydrogenase 1 17 42549214-42555213 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021032, HPA065296 Supported Supported Cytosol Tissue enriched 14 placenta: 98.3 cerebral cortex: 7.1 -MLX bHLHd13, MAD7, MXD7, TCFL4 ENSG00000108788 MLX, MAX dimerization protein 17 42567068-42573239 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025329, HPA052766, HPA064438 Approved Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all duodenum: 47.6 -CNTNAP1 Caspr, CNTNAP, NRXN4, p190 ENSG00000108797 Contactin associated protein 1 17 42682613-42699814 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011772 Approved Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 62.0;smooth muscle: 38.6 endometrium: 19.2 -ABI3 NESH, SSH3BP3 ENSG00000108798 ABI family, member 3 17 49210227-49223225 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017345 Approved Tissue enhanced 0 spleen: 63.1 lymph node: 30.4 -EZH1 KIAA0388, KMT6B ENSG00000108799 Enhancer of zeste 1 polycomb repressive complex 2 subunit 17 42700275-42745049 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005478 Supported Nucleoplasm Expressed in all ovary: 58.5 -DLX4 BP1, DLX7, DLX8, DLX9 ENSG00000108813 Distal-less homeobox 4 17 49968970-49974959 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA059933 Uncertain Approved Nucleoplasm Tissue enhanced 0 placenta: 5.3 skin: 1.2 -PPP1R9B PPP1R6, PPP1R9, SPINO, Spn ENSG00000108819 Protein phosphatase 1, regulatory subunit 9B 17 50133735-50150630 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB022461 Approved Expressed in all cerebral cortex: 76.5 -COL1A1 OI4 ENSG00000108821 Collagen, type I, alpha 1 17 50183289-50201632 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008405, HPA011795 Uncertain Approved Vesicles
Cytosol Expressed in all cervix: 1863.2 -SGCA A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1 ENSG00000108823 Sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 17 50164214-50175931 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007537 Uncertain Tissue enhanced 0 heart muscle: 79.5;skeletal muscle: 181.4 seminal vesicle: 37.7 -PTGES3L-AARSD1 ENSG00000108825 PTGES3L-AARSD1 readthrough 17 42950526-42980528 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021408, HPA022869, HPA023714 Approved Approved Nuclear membrane
Cytosol Tissue enhanced 0 smooth muscle: 7.4 testis: 4.0 -MRPL27 ENSG00000108826 Mitochondrial ribosomal protein L27 17 50367857-50373214 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021416 Approved Expressed in all epididymis: 129.6 -VAT1 FLJ20230, VATI ENSG00000108828 Vesicle amine transport 1 17 43014605-43025123 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045170 Uncertain Expressed in all adrenal gland: 243.0 -LRRC59 FLJ21675, PRO1855 ENSG00000108829 Leucine rich repeat containing 59 17 50375059-50397553 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030827, HPA030829 Supported Validated Endoplasmic reticulum Expressed in all cervix: 91.6 -RND2 ARHN, Rho7, RhoN ENSG00000108830 Rho family GTPase 2 17 43025241-43032036 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 37.1;testis: 30.7 thyroid gland: 11.0 -ALOX12 12S-LOX ENSG00000108839 Arachidonate 12-lipoxygenase 17 6996065-7010736 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010691, CAB019287 Supported Supported Nuclear speckles
Cytosol Group enriched 5 esophagus: 50.5;skin: 26.0 tonsil: 7.1 -HDAC5 FLJ90614, KIAA0600, NY-CO-9 ENSG00000108840 Histone deacetylase 5 17 44076746-44123702 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019400, HPA030991 Approved Supported Nuclear speckles
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 59.2 -ABCC3 cMOAT2, EST90757, MLP2, MOAT-D, MRP3 ENSG00000108846 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 17 50634777-50692252 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037136, HPA048483 Approved Approved Plasma membrane Mixed adrenal gland: 20.8 -LUC7L3 CRA, CREAP-1, CROP, FLJ11063, hLuc7A, LUC7A, OA48-18 ENSG00000108848 LUC7-like 3 pre-mRNA splicing factor 17 50719544-50756213 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018475, HPA018484, HPA020017 Supported Validated Nuclear speckles Expressed in all endometrium: 236.7 -PPY PNP ENSG00000108849 Pancreatic polypeptide 17 43940804-43942468 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB016735, HPA032122 Supported Group enriched 7 epididymis: 7.6;pancreas: 35.3;parathyroid gland: 33.0;rectum: 8.4;skin: 8.3 colon: 2.6 -MPP2 DKFZp761D0712, DLG2 ENSG00000108852 Membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 17 43875357-43909711 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026486 Approved Approved Mitochondria
Cytosol Tissue enhanced 0 cerebral cortex: 38.0;epididymis: 34.3;parathyroid gland: 43.0 testis: 24.1 -SMURF2 ENSG00000108854 SMAD specific E3 ubiquitin protein ligase 2 17 64542295-64662068 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071508 Approved Supported Nuclear speckles Mixed testis: 32.7 -DUSP3 VHR ENSG00000108861 Dual specificity phosphatase 3 17 43766121-43778988 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063616 Supported Nucleoplasm
Cytosol Expressed in all seminal vesicle: 99.6 -CACNG1 CACNLG ENSG00000108878 Calcium channel, voltage-dependent, gamma subunit 1 17 67044590-67056797 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 25 skeletal muscle: 113.5 esophagus: 4.4 -EFTUD2 SNRNP116, Snrp116, Snu114, U5-116KD ENSG00000108883 Elongation factor Tu GTP binding domain containing 2 17 44849943-44899662 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022021 Supported Supported Nucleoplasm
Cytosol Expressed in all testis: 47.5 -HLF MGC33822 ENSG00000108924 Hepatic leukemia factor 17 55265012-55325065 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA068156, HPA071210 Validated Nucleus Mixed cerebral cortex: 65.6 -SLC16A6 MCT6, MCT7 ENSG00000108932 Solute carrier family 16, member 6 17 68267026-68291267 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054459, HPA066328 Uncertain Approved Vesicles Tissue enhanced 0 epididymis: 39.8 esophagus: 12.1 -PRKAR1A CNC1, PRKAR1, TSE1 ENSG00000108946 Protein kinase, cAMP-dependent, regulatory, type I, alpha 17 68511780-68551319 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019378, HPA049979 Approved Approved Cytosol Expressed in all parathyroid gland: 555.0 -EFNB3 EPLG8, LERK-8 ENSG00000108947 Ephrin-B3 17 7705202-7711378 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001623 Approved Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 48.8 endometrium: 17.3 -FAM20A DKFZp434F2322 ENSG00000108950 Family with sequence similarity 20, member A 17 68535113-68601389 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048964 Approved Mixed lung: 8.8 -YWHAE FLJ45465 ENSG00000108953 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 17 1344272-1400378 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008445, CAB016200, CAB021109, CAB047350 Approved Uncertain Cytosol Expressed in all cerebral cortex: 452.9 -MMD MMA, PAQR11 ENSG00000108960 Monocyte to macrophage differentiation-associated 17 55392613-55421992 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026978 Approved Vesicles Tissue enhanced 0 adipose tissue: 141.1 cerebral cortex: 73.3 -RANGRF HSPC165, HSPC236, MOG1, RANGNRF ENSG00000108961 RAN guanine nucleotide release factor 17 8288497-8290092 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057280, HPA057888 Approved Supported Nucleoplasm Expressed in all testis: 71.8 -DPH1 DPH2L, DPH2L1, OVCA1 ENSG00000108963 Diphthamide biosynthesis 1 17 2030110-2043430 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069750 Approved Nucleoplasm
Cell Junctions Expressed in all fallopian tube: 30.8 -MAP2K6 MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3 ENSG00000108984 Mitogen-activated protein kinase kinase 6 17 69414698-69543331 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007744, HPA031134 Approved Supported Nucleus
Cytosol Mixed cervix: 39.1 -DHRS7B CGI-93, DKFZp566O084, MGC8916, SDR32C1 ENSG00000109016 Dehydrogenase/reductase (SDR family) member 7B 17 21123364-21193265 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012132, HPA016873 Uncertain Approved Plasma membrane
Cell Junctions
Cytosol Expressed in all parathyroid gland: 49.4 -WSB1 DKFZp564A122, DKFZp564B0482, SWIP1 ENSG00000109046 WD repeat and SOCS box containing 1 17 27294076-27315926 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA003293 Approved Approved Mitochondria Expressed in all placenta: 106.3 -RCVRN RCV1 ENSG00000109047 Recoverin 17 9896320-9905621 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015783, CAB022363 Supported Not detected cerebral cortex: 0.3 -MYH1 MGC133384, MYHa, MyHC-2X/D, MYHSA1 ENSG00000109061 Myosin, heavy chain 1, skeletal muscle, adult 17 10492307-10518543 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001349, CAB010759 Supported Tissue enriched 735 skeletal muscle: 2754.7 esophagus: 3.7 -SLC9A3R1 EBP50, NHERF ENSG00000109062 Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 17 74748652-74769353 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001962, HPA009672, HPA027247 Supported Approved Vesicles
Plasma membrane
Microtubule organizing center Expressed in all small intestine: 308.5 -MYH3 HEMHC, MYHC-EMB, MYHSE1, SMHCE ENSG00000109063 Myosin, heavy chain 3, skeletal muscle, embryonic 17 10628526-10657309 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021808 Supported Group enriched 5 esophagus: 9.7;prostate: 38.1;seminal vesicle: 24.4 testis: 4.3 -NAT9 DKFZP564C103 ENSG00000109065 N-acetyltransferase 9 (GCN5-related, putative) 17 74770547-74776367 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021820, HPA057149 Approved Approved Nucleoplasm Expressed in all adrenal gland: 39.3 -TMEM104 FLJ00021, FLJ20255 ENSG00000109066 Transmembrane protein 104 17 74776483-74839779 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044330 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 14.7 -VTN VN ENSG00000109072 Vitronectin 17 28367276-28373091 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016695, CAB016765, HPA060933 Supported Supported Endoplasmic reticulum
Vesicles Tissue enriched 28 liver: 2540.4 gallbladder: 91.6 -TNFAIP1 B12, B61, BTBD34, EDP1, MGC2317 ENSG00000109079 Tumor necrosis factor, alpha-induced protein 1 (endothelial) 17 28335602-28347009 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013333, HPA014641 Uncertain Validated Nucleoli Expressed in all spleen: 70.2 -IFT20 ENSG00000109083 Intraflagellar transport 20 17 28328325-28335489 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021376 Approved Approved Microtubules Expressed in all testis: 78.3 -TMEM97 MAC30 ENSG00000109084 Transmembrane protein 97 17 28319095-28328685 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044795 Approved Approved Nuclear membrane
Plasma membrane
Cytosol Expressed in all testis: 109.7 -CDR2L HUMPPA ENSG00000109089 Cerebellar degeneration-related protein 2-like 17 74987632-75005800 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022015 Approved Approved Cytosol Mixed duodenum: 23.1 -PMP22 GAS3, HNPP, Sp110 ENSG00000109099 Peripheral myelin protein 22 17 15229777-15265326 Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all small intestine: 314.4 -FOXN1 FKHL20, RONU, WHN ENSG00000109101 Forkhead box N1 17 28506243-28538896 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 esophagus: 7.2;skin: 35.3 tonsil: 5.3 -UNC119 HRG4, POC7, POC7A ENSG00000109103 Unc-119 lipid binding chaperone 17 28546707-28552668 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041912 Supported Expressed in all testis: 45.4 -ALDOC ENSG00000109107 Aldolase C, fructose-bisphosphate 17 28573115-28577264 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003282, CAB020828, HPA067442 Supported Supported Approved Nucleus
Nucleoli fibrillar center
Vesicles
Cytosol Tissue enriched 7 cerebral cortex: 768.7 heart muscle: 110.6 -SUPT6H KIAA0162, SPT6H ENSG00000109111 SPT6 homolog, histone chaperone 17 28662091-28702684 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012416, HPA036382 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 61.1 -RAB34 RAB39, RAH ENSG00000109113 RAB34, member RAS oncogene family 17 28714281-28718429 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021366 Approved Expressed in all endometrium: 132.7 -PHF12 KIAA1523, PF1 ENSG00000109118 PHD finger protein 12 17 28905250-28951771 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021410, HPA021452 Approved Validated Nucleoplasm Expressed in all prostate: 26.7 -PHOX2B NBPhox, Phox2b, PMX2B ENSG00000109132 Paired-like homeobox 2b 4 41744082-41748970 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA074325 Supported Nucleoplasm Tissue enriched 8 adrenal gland: 10.4 small intestine: 1.2 -TMEM33 FLJ10525 ENSG00000109133 Transmembrane protein 33 4 41935120-41960572 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 39.8 -GABRA4 ENSG00000109158 Gamma-aminobutyric acid (GABA) A receptor, alpha 4 4 46918900-46994407 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 12 cerebral cortex: 15.1 heart muscle: 1.2 -GNRHR GRHR, LHRHR ENSG00000109163 Gonadotropin-releasing hormone receptor 4 67739328-67754360 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA013424 Supported Tissue enhanced 0 parathyroid gland: 1.2 adrenal gland: 1.0 -SLAIN2 FLJ21611, KIAA1458 ENSG00000109171 SLAIN motif family, member 2 4 48341322-48426212 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035824, HPA063599 Approved Validated Centrosome
Cytosol Expressed in all testis: 72.6 -OCIAD1 Asrij, FLJ20455, OCIA, TPA018 ENSG00000109180 OCIA domain containing 1 4 48805212-48861817 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044803 Approved Approved Mitochondria Expressed in all cerebral cortex: 326.5 -UGT2B10 ENSG00000109181 UDP glucuronosyltransferase 2 family, polypeptide B10 4 68815993-68831196 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045108 Uncertain Tissue enriched 87 liver: 303.2 gallbladder: 3.4 -CWH43 CWH43-C, FLJ21511 ENSG00000109182 Cell wall biogenesis 43 C-terminal homolog 4 48986247-49062081 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042814, HPA048140 Uncertain Tissue enhanced 0 prostate: 69.1 skin: 29.7 -DCUN1D4 KIAA0276 ENSG00000109184 DCN1, defective in cullin neddylation 1, domain containing 4 4 51843000-51916837 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036483, HPA036484 Uncertain Approved Nucleus
Vesicles Expressed in all testis: 28.7 -USP46 FLJ12552 ENSG00000109189 Ubiquitin specific peptidase 46 4 52590972-52659335 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007288, CAB076369, CAB076370 Uncertain Validated Nucleoli Expressed in all cerebral cortex: 44.8 -SULT1E1 EST, STE ENSG00000109193 Sulfotransferase family 1E, estrogen-preferring, member 1 4 69810780-69860152 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028213, HPA028728, CAB047344 Supported Group enriched 7 duodenum: 28.4;liver: 18.7;skin: 7.6;small intestine: 30.3 adrenal gland: 3.1 -ODAM APin, FLJ20513 ENSG00000109205 Odontogenic, ameloblast asssociated 4 70196496-70204576 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA036543 Supported Nucleoplasm
Cytosol Tissue enriched 14 salivary gland: 136.9 smooth muscle: 10.0 -SMR3A PBI, PRL5, PROL5 ENSG00000109208 Submaxillary gland androgen regulated protein 3A 4 70360761-70367158 Predicted secreted proteins Evidence at protein level Evidence at protein level No evidence HPA044567 Supported Tissue enriched 25 salivary gland: 24.3 thyroid gland: 0.9 -CHIC2 BTL ENSG00000109220 Cysteine-rich hydrophobic domain 2 4 54009789-54064690 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026782 Uncertain Expressed in all testis: 62.9 -NMU ENSG00000109255 Neuromedin U 4 55595229-55636698 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA025926 Uncertain Group enriched 6 esophagus: 35.0;skin: 45.4 tonsil: 7.1 -KIAA1211 ENSG00000109265 KIAA1211 4 56049073-56328625 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043249, HPA048148 Uncertain Approved Nucleoplasm
Golgi apparatus Tissue enhanced 0 testis: 38.9 small intestine: 22.6 -LAMTOR3 MAP2K1IP1, MAPBP, MAPKSP1, MP1, Ragulator3 ENSG00000109270 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 4 99878336-99894490 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026858 Supported Expressed in all thyroid gland: 57.0 -PF4V1 CXCL4L1, CXCL4V1, SCYB4V1 ENSG00000109272 Platelet factor 4 variant 1 4 73853189-73854155 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052485 Supported Tissue enhanced 0 spleen: 4.0;urinary bladder: 3.0 seminal vesicle: 2.5 -NFKB1 KBF1, NF-kappaB, NF-kB1, NFkappaB, NFKB-p50, p105, p50 ENSG00000109320 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 4 102501329-102617302 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004031, HPA027305 Supported Supported Nucleoplasm
Cytosol Expressed in all bone marrow: 57.0 -AREG AREGB, SDGF ENSG00000109321 Amphiregulin 4 74445134-74455009 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA008720, CAB023519 Approved Approved Mitochondria Tissue enhanced 0 placenta: 461.0 gallbladder: 120.0 -MANBA ENSG00000109323 Mannosidase, beta A, lysosomal 4 102631488-102760994 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA053478 Approved Supported Vesicles Expressed in all parathyroid gland: 36.8 -UBE2D3 UbcH5C ENSG00000109332 Ubiquitin-conjugating enzyme E2D 3 4 102794383-102868896 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003920 Uncertain Approved Plasma membrane
Cytosol Expressed in all bone marrow: 301.5 -MAPK10 JNK3, p493F12, p54bSAPK, PRKM10 ENSG00000109339 Mitogen-activated protein kinase 10 4 86015123-86594131 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022625, HPA060304 Approved Supported Nucleoplasm Tissue enhanced 0 cerebral cortex: 148.5 seminal vesicle: 59.2 -ELF2 EU32, NERF, NERF-1A, NERF-1B, NERF-2 ENSG00000109381 E74-like factor 2 (ets domain transcription factor) 4 139028112-139177218 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006057, HPA071166 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 69.0 -NDUFC1 KFYI ENSG00000109390 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4 139266880-139302551 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA044556 Approved Supported Mitochondria Expressed in all skeletal muscle: 86.7 -UCP1 SLC25A7, UCP ENSG00000109424 Uncoupling protein 1 (mitochondrial, proton carrier) 4 140559434-140568805 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adrenal gland: 3.7 breast: 0.9 -TBC1D9 KIAA0882, MDR1 ENSG00000109436 TBC1 domain family, member 9 (with GRAM domain) 4 140620765-140756120 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000262, HPA006317, HPA006503 Uncertain Supported Approved Nucleoplasm
Cytosol Mixed breast: 64.9 -ZNF330 HSA6591, NOA36 ENSG00000109445 Zinc finger protein 330 4 141220887-141234697 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015705, HPA056325 Uncertain Supported Nucleoli Expressed in all heart muscle: 64.0 -INPP4B ENSG00000109452 Inositol polyphosphate-4-phosphatase type II B 4 142023160-142847432 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037681, HPA037682 Approved Approved Centrosome Mixed testis: 33.1 -GAB1 ENSG00000109458 GRB2-associated binding protein 1 4 143336762-143474568 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049599 Approved Vesicles Expressed in all cerebral cortex: 32.3 -KLHL2 MAV ENSG00000109466 Kelch-like family member 2 4 165207618-165323156 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051637 Uncertain Nucleoplasm
Vesicles Tissue enhanced 0 cerebral cortex: 77.5 thyroid gland: 21.5 -IL2 IL-2, TCGF ENSG00000109471 Interleukin 2 4 122451470-122456725 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level CAB010310 Uncertain Not detected rectum: 0.3 -CPE ENSG00000109472 Carboxypeptidase E 4 165361194-165498320 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003819, CAB024907 Supported Approved Nucleoplasm
Vesicles
Centrosome Expressed in all cerebral cortex: 1564.8 -RPL34 L34 ENSG00000109475 Ribosomal protein L34 4 108620566-108630412 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035139 Uncertain Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all breast: 4590.2 -WFS1 DFNA14, DFNA38, DFNA6, DIDMOAD, WFS ENSG00000109501 Wolfram syndrome 1 (wolframin) 4 6269849-6303265 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029128 Approved Mixed ovary: 61.4 -ANXA10 ANX14 ENSG00000109511 Annexin A10 4 168092515-168187690 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005469 Supported Approved Nucleus
Nucleoli
Vesicles Tissue enriched 7 stomach: 460.7 urinary bladder: 62.8 -GRPEL1 FLJ25609, GrpE, hMGE ENSG00000109519 GrpE-like 1, mitochondrial (E. coli) 4 7058906-7068197 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036647 Supported Supported Mitochondria Expressed in all adrenal gland: 44.1 -GAR1 NOLA1 ENSG00000109534 GAR1 homolog, ribonucleoprotein 4 109815510-109824740 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059098 Supported Supported Nucleus
Nucleoli fibrillar center Expressed in all breast: 22.8 -FRG1 FRG1A, FSG1 ENSG00000109536 FSHD region gene 1 4 189940788-189963204 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 24.6 -CLCN3 ClC-3, CLC3 ENSG00000109572 Chloride channel, voltage-sensitive 3 4 169612633-169723673 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044723 Approved Approved Cytosol Expressed in all cerebral cortex: 104.4 -AADAT KAT2, KATII ENSG00000109576 Aminoadipate aminotransferase 4 170060222-170091699 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037502 Supported Approved Vesicles
Plasma membrane Tissue enhanced 0 liver: 34.6 prostate: 23.3 -GALNT7 GALNAC-T7 ENSG00000109586 Polypeptide N-acetylgalactosaminyltransferase 7 4 173168753-173323967 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064243, HPA065317 Supported Validated Nucleus
Golgi apparatus Mixed stomach: 63.1 -DHX15 DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p ENSG00000109606 DEAH (Asp-Glu-Ala-His) box helicase 15 4 24517441-24584550 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047047 Approved Validated Nuclear speckles Expressed in all parathyroid gland: 100.9 -SOD3 EC-SOD ENSG00000109610 Superoxide dismutase 3, extracellular 4 24789912-24800842 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042110 Supported Tissue enhanced 0 adipose tissue: 179.2 fallopian tube: 66.0 -SEPSECS SLA, SLA/LP ENSG00000109618 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 4 25120014-25160442 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA070409 Approved Vesicles Expressed in all liver: 16.7 -CPZ ENSG00000109625 Carboxypeptidase Z 4 8592660-8619759 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 ovary: 121.2 placenta: 57.7 -TRIM2 CMT2R, KIAA0517, RNF86 ENSG00000109654 Tripartite motif containing 2 4 153152342-153339320 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035853, HPA035854 Supported Approved Centrosome Tissue enhanced 0 cerebral cortex: 155.5 thyroid gland: 110.5 -SLC2A9 Glut9, GLUTX, URATv1 ENSG00000109667 Solute carrier family 2 (facilitated glucose transporter), member 9 4 9771153-10054936 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA066229 Approved Tissue enhanced 0 kidney: 30.9;seminal vesicle: 29.4 duodenum: 11.1 -FBXW7 AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10 ENSG00000109670 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 4 152321259-152536101 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB013793, CAB029987 Supported Supported Nucleoplasm
Vesicles Expressed in all skin: 87.7 -NEIL3 FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3 ENSG00000109674 Nei-like DNA glycosylase 3 4 177309836-177362943 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA065761 Validated Nucleoplasm Mixed bone marrow: 4.4 -TBC1D19 FLJ11082 ENSG00000109680 TBC1 domain family, member 19 4 26576437-26755351 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039592 Approved Approved Nucleoplasm
Nuclear membrane Mixed parathyroid gland: 22.7 -CLNK MIST ENSG00000109684 Cytokine-dependent hematopoietic cell linker 4 10486395-10684865 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035671, HPA035672 Uncertain Uncertain Vesicles Tissue enhanced 0 kidney: 5.8 lymph node: 3.5 -WHSC1 MMSET, NSD2 ENSG00000109685 Wolf-Hirschhorn syndrome candidate 1 4 1871424-1982207 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015801, CAB068246, CAB068247 Supported Supported Nucleus Expressed in all testis: 66.9 -SH3D19 DKFZp434D0215, EBP, EVE1, Kryn, SH3P19 ENSG00000109686 SH3 domain containing 19 4 151102751-151325632 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016424, HPA058562 Approved Supported Nucleoplasm
Cytosol Mixed gallbladder: 99.9 -STIM2 ENSG00000109689 Stromal interaction molecule 2 4 26857678-27025381 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036933, CAB037196, HPA057511 Supported Approved Vesicles Expressed in all gallbladder: 44.5 -NKX3-2 BAPX1, NKX3.2, NKX3B ENSG00000109705 NK3 homeobox 2 4 13540830-13545050 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027564 Approved Approved Nucleoplasm Tissue enhanced 0 spleen: 2.8 smooth muscle: 1.6 -MFSD10 IT10C3, TETRAN ENSG00000109736 Major facilitator superfamily domain containing 10 4 2930561-2934859 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043209 Uncertain Approved Nucleoplasm
Nuclear membrane Expressed in all bone marrow: 41.3 -GLRB ENSG00000109738 Glycine receptor, beta 4 157076057-157172090 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052363 Approved Tissue enhanced 0 cerebral cortex: 62.2;parathyroid gland: 62.0 cervix: 14.0 -BST1 CD157 ENSG00000109743 Bone marrow stromal cell antigen 1 4 15702950-15738313 CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050121 Uncertain Tissue enhanced 0 bone marrow: 105.7 duodenum: 56.4 -RAPGEF2 DKFZP586O1422, KIAA0313, PDZ-GEF1, PDZGEF1, RA-GEF ENSG00000109756 Rap guanine nucleotide exchange factor (GEF) 2 4 159104178-159360169 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057169 Approved Nucleoplasm
Centrosome Expressed in all thyroid gland: 109.5 -HGFAC HGFA, HGFAP ENSG00000109758 HGF activator 4 3441887-3449495 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058279, HPA059076 Supported Tissue enriched 14 liver: 28.7 testis: 2.0 -SNX25 SBBI31 ENSG00000109762 Sorting nexin 25 4 185204237-185370185 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036928 Uncertain Approved Vesicles Expressed in all lung: 42.7 -LRP2BP DKFZp761O0113 ENSG00000109771 LRP2 binding protein 4 185363879-185395899 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036664, HPA036665 Approved Tissue enhanced 0 fallopian tube: 12.5;testis: 20.2 cerebral cortex: 6.3 -UFSP2 C4orf20, FLJ11200 ENSG00000109775 UFM1-specific peptidase 2 4 185399540-185425985 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039985, HPA043298 Approved Approved Nucleus
Cytosol Expressed in all thyroid gland: 53.8 -KLF3 BKLF ENSG00000109787 Kruppel-like factor 3 (basic) 4 38664196-38701042 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049512, HPA065054 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 62.2 -KLHL5 ENSG00000109790 Kelch-like family member 5 4 39045039-39126857 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA013958 Approved Expressed in all seminal vesicle: 90.3 -FAM149A DKFZP564J102, MST119, MSTP119 ENSG00000109794 Family with sequence similarity 149, member A 4 186104419-186172667 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA055004 Uncertain Approved Nucleus Mixed kidney: 36.8 -NCAPG CAP-G, FLJ12450, hCAP-G, YCG1 ENSG00000109805 Non-SMC condensin I complex, subunit G 4 17810902-17844862 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039613 Uncertain Mixed testis: 10.4 -UGDH ENSG00000109814 UDP-glucose 6-dehydrogenase 4 39498755-39528311 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034444, HPA036656, HPA036657 Supported Validated Nucleoplasm Expressed in all colon: 97.7 -PPARGC1A PGC1, PGC1A, PPARGC1 ENSG00000109819 Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 4 23755041-23904089 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA063136 Supported Nucleoplasm Mixed kidney: 28.9 -DDX25 GRTH ENSG00000109832 DEAD (Asp-Glu-Ala-Asp) box helicase 25 11 125903376-125928829 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020137 Supported Group enriched 8 cerebral cortex: 10.0;testis: 22.3 fallopian tube: 2.1 -CRYAB CRYA2, HSPB5 ENSG00000109846 Crystallin, alpha B 11 111908565-111923722 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002053, CAB040560, HPA057100 Supported Validated Plasma membrane
Cytosol Tissue enhanced 0 heart muscle: 3940.2 cerebral cortex: 1892.7 -DBX1 ENSG00000109851 Developing brain homeobox 1 11 20156155-20160613 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA039802 Uncertain Not detected testis: 0.2 -HTATIP2 CC3, FLJ26963, SDR44U1, TIP30 ENSG00000109854 HIV-1 Tat interactive protein 2, 30kDa 11 20363685-20383783 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006417, HPA024321 Approved Supported Cytosol Expressed in all duodenum: 139.0 -CTSC DPP1, PALS, PLS ENSG00000109861 Cathepsin C 11 88293592-88337787 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025364, HPA066610, HPA068434 Supported Supported Vesicles Expressed in all lung: 390.6 -CCDC34 L15, NY-REN-41, RAMA3 ENSG00000109881 Coiled-coil domain containing 34 11 27330827-27363868 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037574 Uncertain Approved Nuclear membrane
Nucleoli fibrillar center Tissue enhanced 0 testis: 54.6 fallopian tube: 13.4 -ZBTB16 PLZF, ZNF145 ENSG00000109906 Zinc finger and BTB domain containing 16 11 114059593-114250676 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001499, CAB004540 Uncertain Mixed ovary: 59.6 -ELP4 C11orf19, PAXNEB ENSG00000109911 Elongator acetyltransferase complex subunit 4 11 31509750-31783998 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038572, HPA038573 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 20.1 -ZPR1 ZNF259 ENSG00000109917 ZPR1 zinc finger 11 116773799-116788050 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022596, HPA030979 Uncertain Approved Vesicles Expressed in all testis: 43.6 -MTCH2 SLC25A50 ENSG00000109919 Mitochondrial carrier 2 11 47617315-47642623 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038390 Approved Supported Mitochondria Expressed in all testis: 137.7 -FNBP4 KIAA1014 ENSG00000109920 Formin binding protein 4 11 47716517-47767443 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039485, HPA040029 Supported Validated Nuclear speckles Expressed in all spleen: 48.9 -TECTA DFNA12, DFNA8, DFNB21 ENSG00000109927 Tectorin alpha 11 121101173-121191493 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018870 Approved Tissue enhanced 0 cerebral cortex: 2.7 parathyroid gland: 2.0 -SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase 11 121292453-121308694 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066283, HPA070248 Approved Approved Nucleoplasm
Endoplasmic reticulum
Plasma membrane
Cytosol Expressed in all liver: 193.1 -CRTAM CD355 ENSG00000109943 Cytotoxic and regulatory T cell molecule 11 122838500-122872639 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054595 Uncertain Tissue enhanced 0 lymph node: 10.0 spleen: 5.0 -C11orf63 FLJ23554 ENSG00000109944 Chromosome 11 open reading frame 63 11 122882528-122959798 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039612, HPA040344 Supported Nucleoplasm
Golgi apparatus Tissue enhanced 0 testis: 63.4 parathyroid gland: 14.4 -B3GAT1 CD57, GlcAT-P, HNK-1, LEU7, NK-1 ENSG00000109956 Beta-1,3-glucuronyltransferase 1 11 134378504-134411918 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB002500, CAB010893, HPA069468 Supported Validated Vesicles Tissue enriched 11 cerebral cortex: 115.7 thyroid gland: 10.3 -HSPA8 HSC70, HSC71, HSP73, HSPA10 ENSG00000109971 Heat shock 70kDa protein 8 11 123057489-123063230 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002056, HPA052504 Uncertain Uncertain Nucleoplasm
Vesicles Expressed in all cerebral cortex: 1122.1 -P2RX3 P2X3 ENSG00000109991 Purinergic receptor P2X, ligand gated ion channel, 3 11 57338374-57370600 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057776 Uncertain Tissue enhanced 0 heart muscle: 2.0;testis: 6.1 liver: 0.9 -VWA5A BCSC-1, LOH11CR2A ENSG00000110002 Von Willebrand factor A domain containing 5A 11 124115362-124147721 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037813, HPA037814, HPA061500 Uncertain Validated Nucleus Expressed in all gallbladder: 48.9 -DNAJC4 HSPF2, MCG18 ENSG00000110011 DnaJ (Hsp40) homolog, subfamily C, member 4 11 64230278-64234286 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011947 Uncertain Expressed in all testis: 136.3 -SIAE CSE-C, LSE, MGC87009, YSG2 ENSG00000110013 Sialic acid acetylesterase 11 124633113-124695707 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038052, HPA038053 Approved Expressed in all rectum: 116.8 -SNX15 ENSG00000110025 Sorting nexin 15 11 65027408-65040572 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038955 Approved Supported Nucleoli
Cytosol Expressed in all cerebral cortex: 24.8 -LPXN LDPL ENSG00000110031 Leupaxin 11 58526871-58578220 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043741, CAB046478, HPA061441 Supported Validated Nuclear speckles
Focal adhesion sites
Cytosol Expressed in all tonsil: 111.2 -DTX4 KIAA0937, RNF155 ENSG00000110042 Deltex 4, E3 ubiquitin ligase 11 59171430-59208587 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056760, HPA059294 Uncertain Approved Approved Vesicles Mixed lung: 27.4 -ATG2A KIAA0404 ENSG00000110046 Autophagy related 2A 11 64894546-64917248 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038715 Uncertain Approved Nucleus
Vesicles
Cytosol Expressed in all bone marrow: 39.0 -EHD1 FLJ42622, FLJ44618, H-PAST, HPAST1, PAST1 ENSG00000110047 EH-domain containing 1 11 64851642-64888296 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049890, HPA049986, HPA066751, HPA067747 Approved Supported Plasma membrane Expressed in all testis: 153.1 -OSBP OSBP1 ENSG00000110048 Oxysterol binding protein 11 59574398-59616144 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039227, HPA043625 Supported Validated Nucleus
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 72.8 -UNC93B1 UNC93 ENSG00000110057 Unc-93 homolog B1 (C. elegans) 11 67991104-68004982 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038716, HPA038717, HPA042803 Approved Approved Nucleoplasm Mixed spleen: 56.6 -PUS3 FKSG32 ENSG00000110060 Pseudouridylate synthase 3 11 125893485-125903221 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038040, HPA063802 Uncertain Approved Nucleus
Cytosol Expressed in all liver: 16.9 -DCPS HINT-5, HSL1, HSPC015 ENSG00000110063 Decapping enzyme, scavenger 11 126303752-126345749 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039632, HPA058597 Supported Supported Nucleoplasm
Cytosol Expressed in all lymph node: 24.9 -SUV420H1 CGI-85, KMT5B ENSG00000110066 Suppressor of variegation 4-20 homolog 1 (Drosophila) 11 68154863-68213828 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063648 Supported Nucleus Expressed in all thyroid gland: 51.9 -FOXRED1 H17 ENSG00000110074 FAD-dependent oxidoreductase domain containing 1 11 126269055-126278131 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039620, HPA046192 Uncertain Supported Mitochondria Expressed in all liver: 19.0 -PPP6R3 C11orf23, DKFZp781E17107, DKFZp781E2374, DKFZp781O2362, FLJ11058, FLJ43065, KIAA1558, MGC125711, MGC125712, PP6R3, SAP190, SAPL, SAPLa, SAPS3 ENSG00000110075 Protein phosphatase 6, regulatory subunit 3 11 68460731-68615334 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017183, HPA038467, HPA038468 Supported Validated Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 92.1 -NRXN2 ENSG00000110076 Neurexin 2 11 64606174-64723188 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051470 Approved Nucleus
Nuclear membrane
Cytosol Tissue enriched 8 cerebral cortex: 143.0 testis: 17.0 -MS4A6A CD20L3, MS4A6 ENSG00000110077 Membrane-spanning 4-domains, subfamily A, member 6A 11 60172014-60184666 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA011391, HPA076623 Approved Approved Vesicles Expressed in all lymph node: 115.2 -MS4A4A CD20L1, MS4A4, MS4A7 ENSG00000110079 Membrane-spanning 4-domains, subfamily A, member 4A 11 60280541-60308972 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029323 Approved Tissue enhanced 0 placenta: 101.4 adipose tissue: 62.8 -ST3GAL4 CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, STZ ENSG00000110080 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 11 126355640-126440344 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049827 Approved Mixed adrenal gland: 105.8 -CPT1A CPT1, CPT1-L, L-CPT1 ENSG00000110090 Carnitine palmitoyltransferase 1A (liver) 11 68754620-68844410 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008835 Supported Supported Mitochondria Expressed in all small intestine: 80.5 -CCND1 BCL1, D11S287E, PRAD1, U21B31 ENSG00000110092 Cyclin D1 11 69641087-69654474 Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000024, HPA027802 Uncertain Supported Nucleoplasm Tissue enhanced 0 parathyroid gland: 335.1 skin: 140.9 -CCDC86 MGC2574 ENSG00000110104 Coiled-coil domain containing 86 11 60842071-60851081 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041117, HPA041540 Supported Validated Nucleus
Nucleoli Tissue enriched 11 parathyroid gland: 611.5 testis: 58.2 -PRPF19 hPSO4, NMP200, PRP19, PSO4, UBOX4 ENSG00000110107 Pre-mRNA processing factor 19 11 60890730-60906588 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012448, HPA038051, HPA059070 Supported Validated Nuclear speckles Expressed in all cerebral cortex: 129.3 -TMEM109 MGC5508 ENSG00000110108 Transmembrane protein 109 11 60913874-60923443 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011785 Approved Approved Nuclear membrane
Cytosol Expressed in all endometrium: 94.2 -CCKBR ENSG00000110148 Cholecystokinin B receptor 11 6259736-6272127 Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 14 cerebral cortex: 13.7;pancreas: 5.4;stomach: 16.1 prostate: 0.8 -HPX ENSG00000110169 Hemopexin 11 6431049-6442617 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016725 Supported Tissue enriched 508 liver: 2610.6 breast: 5.1 -TRIM3 BERP, HAC1, RNF22, RNF97 ENSG00000110171 Tripartite motif containing 3 11 6448613-6474459 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043396, HPA048233 Uncertain Approved Mitochondria Mixed duodenum: 17.7 -CHORDC1 CHP1 ENSG00000110172 Cysteine and histidine-rich domain (CHORD) containing 1 11 90201160-90223364 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041040 Approved Supported Cytosol Expressed in all placenta: 31.2 -FOLR1 FOLR ENSG00000110195 Folate receptor 1 (adult) 11 72189558-72196301 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077030 Approved Nuclear membrane Tissue enhanced 0 cervix, uterine: 176.8;fallopian tube: 289.8;lung: 284.9 kidney: 154.6 -ANAPC15 APC15, C11orf51, DKFZP564M082, HSPC020 ENSG00000110200 Anaphase promoting complex subunit 15 11 72106378-72112780 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036596 Approved Approved Nucleoplasm
Vesicles Expressed in all testis: 78.0 -FOLR3 FR-G ENSG00000110203 Folate receptor 3 (gamma) 11 72114869-72139892 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 56.9 appendix: 12.7 -PANX1 MRS1, PX1, UNQ2529 ENSG00000110218 Pannexin 1 11 94128928-94181972 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016930 Uncertain Validated Plasma membrane Expressed in all testis: 19.4 -ARHGEF17 KIAA0337, p164-RhoGEF, TEM4 ENSG00000110237 Rho guanine nucleotide exchange factor (GEF) 17 11 73308289-73369091 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007991 Uncertain Approved Cytosol Expressed in all parathyroid gland: 37.0 -APOA5 APOA-V, RAP3 ENSG00000110243 Apolipoprotein A-V 11 116789367-116792420 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 235 liver: 256.9 testis: 1.0 -APOA4 ENSG00000110244 Apolipoprotein A-IV 11 116820700-116823306 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001352, HPA002549, CAB068250, CAB068251, CAB068252 Supported Approved Vesicles Group enriched 129 duodenum: 2273.3;small intestine: 3513.5 liver: 22.3 -APOC3 ENSG00000110245 Apolipoprotein C-III 11 116829706-116833072 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 liver: 8606.5 small intestine: 1203.1 -CEP164 KIAA1052, NPHP15 ENSG00000110274 Centrosomal protein 164kDa 11 117314557-117413268 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037605, HPA037606 Uncertain Supported Nucleoplasm
Centrosome Mixed testis: 34.3 -RNF141 ZFP26, ZNF230 ENSG00000110315 Ring finger protein 141 11 10511678-10541230 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018133 Approved Approved Nucleoplasm
Microtubules Expressed in all testis: 129.5 -CEP126 KIAA1377 ENSG00000110318 Centrosomal protein 126kDa 11 101915015-102001058 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038381, HPA038399 Uncertain Nucleoplasm
Cytosol Tissue enhanced 0 testis: 17.7 fallopian tube: 12.9 -EIF4G2 DAP5, NAT1, p97 ENSG00000110321 Eukaryotic translation initiation factor 4 gamma, 2 11 10797050-10809110 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005163, HPA006773, HPA016965 Approved Validated Cytosol Expressed in all parathyroid gland: 638.5 -IL10RA CD210, CD210a, CDW210A, HIL-10R, IL10R ENSG00000110324 Interleukin 10 receptor, alpha 11 117986348-118001483 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 spleen: 82.4 lymph node: 54.1 -GALNT18 GalNAc-T18, GALNT15, GALNTL4, MGC71806 ENSG00000110328 Polypeptide N-acetylgalactosaminyltransferase 18 11 11270876-11622005 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012955 Approved Approved Mitochondria Tissue enhanced 0 thyroid gland: 59.0 lung: 43.2 -BIRC2 API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48 ENSG00000110330 Baculoviral IAP repeat containing 2 11 102347211-102378670 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005513, CAB020661 Supported Supported Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all testis: 45.6 -UBE4A E4, KIAA0126, UBOX2, UFD2 ENSG00000110344 Ubiquitination factor E4A 11 118359585-118399211 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055035, HPA064010 Approved Supported Nuclear speckles Expressed in all parathyroid gland: 42.9 -DDX6 HLR2, RCK ENSG00000110367 DEAD (Asp-Glu-Ala-Asp) box helicase 6 11 118747766-118791149 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004668, HPA024201, HPA026644 Approved Supported Cytosol
Cytoplasmic bodies Expressed in all cerebral cortex: 65.6 -UPK2 MGC138598, UP2, UPII ENSG00000110375 Uroplakin 2 11 118925164-118958559 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043312, HPA061106 Supported Tissue enriched 46 urinary bladder: 71.3 adipose tissue: 1.5 -CBL c-Cbl, CBL2, RNF55 ENSG00000110395 Cbl proto-oncogene, E3 ubiquitin protein ligase 11 119206276-119308149 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004350, HPA027956 Supported Supported Cytosol Mixed testis: 33.1 -PVRL1 CD111, CLPED1, ED4, HIgR, HVEC, OFC7, PRR, PRR1, PVRR1, SK-12 ENSG00000110400 Poliovirus receptor-related 1 (herpesvirus entry mediator C) 11 119623408-119729084 CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB016135, HPA026846 Approved Tissue enhanced 0 esophagus: 109.0;skin: 162.1 cerebral cortex: 50.5 -HIPK3 DYRK6, FIST3, PKY, YAK1 ENSG00000110422 Homeodomain interacting protein kinase 3 11 33256672-33357023 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028069 Approved Supported Nuclear bodies
Cytosol Expressed in all parathyroid gland: 124.8 -KIAA1549L C11orf41, C11orf69, G2, MGC34830 ENSG00000110427 KIAA1549-like 11 33542072-33674102 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051594 Approved Nucleoplasm Group enriched 40 cerebral cortex: 35.0;parathyroid gland: 143.5 skin: 2.2 -FBXO3 FBA, FBX3 ENSG00000110429 F-box protein 3 11 33740939-33774543 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002467 Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 88.0 -PDHX DLDBP, E3BP, OPDX, PDX1, proX ENSG00000110435 Pyruvate dehydrogenase complex, component X 11 34915829-35020591 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038484, HPA038485 Supported Approved Nucleus
Plasma membrane
Mitochondria Expressed in all testis: 51.8 -SLC1A2 EAAT2, GLT-1 ENSG00000110436 Solute carrier family 1 (glial high affinity glutamate transporter), member 2 11 35251206-35420063 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002574, HPA009172 Supported Tissue enriched 30 cerebral cortex: 367.1 liver: 12.2 -COMMD9 FLJ31106, HSPC166 ENSG00000110442 COMM domain containing 9 11 36269284-36289449 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009142 Uncertain Approved Nucleus
Golgi apparatus
Cytosol Expressed in all cerebral cortex: 48.4 -SLC15A3 hPTR3, PHT2 ENSG00000110446 Solute carrier family 15 (oligopeptide transporter), member 3 11 60937083-60952530 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047880, HPA057642 Approved Supported Vesicles Expressed in all lung: 102.3 -CD5 LEU1, T1 ENSG00000110448 CD5 molecule 11 61102395-61127852 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015392, CAB020308, HPA043416, HPA060839 Supported Tissue enhanced 0 appendix: 31.0;lymph node: 43.6 tonsil: 21.1 -ACCS ACS, PHACS ENSG00000110455 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 11 44065925-44084222 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018873, HPA021654 Approved Approved Golgi apparatus Mixed spleen: 19.1 -SCGB2A2 MGB1, MGC71974, UGB2 ENSG00000110484 Secretoglobin, family 2A, member 2 11 62270155-62273156 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB026270 Supported Tissue enriched 7 breast: 3633.4 cervix: 504.4 -MDK FLJ27379, MK, NEGF2 ENSG00000110492 Midkine (neurite growth-promoting factor 2) 11 46380756-46383837 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010055, HPA057126 Uncertain Approved Vesicles Expressed in all ovary: 524.0 -AMBRA1 DCAF3, FLJ20294, KIAA1736, WDR94 ENSG00000110497 Autophagy/beclin-1 regulator 1 11 46396414-46594125 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017825, HPA038535 Approved Approved Vesicles
Mitochondria Expressed in all parathyroid gland: 26.6 -MADD DENN, KIAA0358, RAB3GEP ENSG00000110514 MAP-kinase activating death domain 11 47269161-47330031 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038568 Uncertain Supported Plasma membrane
Cytosol Expressed in all cerebral cortex: 104.2 -PTPMT1 DUSP23, MOSP, PLIP ENSG00000110536 Protein tyrosine phosphatase, mitochondrial 1 11 47565430-47573461 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040348, HPA043932 Approved Supported Mitochondria Expressed in all testis: 89.5 -NAA40 FLJ13848, NAT11 ENSG00000110583 N(alpha)-acetyltransferase 40, NatD catalytic subunit 11 63938959-63957328 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037816 Uncertain Approved Nuclear bodies Expressed in all parathyroid gland: 28.2 -CARS CARS1 ENSG00000110619 Cysteinyl-tRNA synthetase 11 3000922-3057613 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737 Supported Validated Cytosol Expressed in all thyroid gland: 28.2 -SLC22A18 BWR1A, BWSCR1A, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5 ENSG00000110628 Solute carrier family 22, member 18 11 2899721-2925246 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067812, HPA071461 Approved Tissue enhanced 0 duodenum: 44.5;small intestine: 32.4 colon: 10.5 -CD81 TAPA-1, TAPA1, TSPAN28 ENSG00000110651 CD81 molecule 11 2376177-2397419 CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002507, HPA007234 Supported Supported Plasma membrane Expressed in all seminal vesicle: 2246.2 -SLC35F2 FLJ13018 ENSG00000110660 Solute carrier family 35, member F2 11 107790991-107928293 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048185, HPA050695 Uncertain Approved Mitochondria Mixed prostate: 33.0 -C11orf21 ENSG00000110665 Chromosome 11 open reading frame 21 11 2295645-2303049 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037607 Approved Tissue enhanced 0 bone marrow: 32.4;spleen: 17.9 lymph node: 16.1 -ELMOD1 DKFZp547C176 ENSG00000110675 ELMO/CED-12 domain containing 1 11 107591091-107666779 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038434, HPA038435 Supported Nucleoplasm
Cytosol Group enriched 15 cerebral cortex: 71.6;skin: 36.8 fallopian tube: 3.5 -CALCA CALC1 ENSG00000110680 Calcitonin-related polypeptide alpha 11 14966668-14972354 Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 77 parathyroid gland: 832.9;thyroid gland: 181.9 kidney: 6.6 -SOX6 ENSG00000110693 SRY (sex determining region Y)-box 6 11 15966449-16739591 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001923, HPA003908 Approved Approved Nucleoplasm Tissue enhanced 0 testis: 25.8 bone marrow: 16.6 -C11orf58 SMAP ENSG00000110696 Chromosome 11 open reading frame 58 11 16613132-16756881 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036591, HPA076406 Uncertain Approved Nucleoplasm
Endoplasmic reticulum Expressed in all thyroid gland: 217.3 -PITPNM1 DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1 ENSG00000110697 Phosphatidylinositol transfer protein, membrane-associated 1 11 67491768-67506263 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060227, HPA062757 Approved Supported Cytosol
Cytoplasmic bodies Expressed in all fallopian tube: 36.7 -RPS13 S13 ENSG00000110700 Ribosomal protein S13 11 17074389-17077787 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005985 Uncertain Approved Nuclear bodies Expressed in all ovary: 2360.7 -AIP ARA9, FKBP16, XAP2 ENSG00000110711 Aryl hydrocarbon receptor interacting protein 11 67483041-67491103 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033674, HPA050217, CAB069477 Approved Supported Cytosol Expressed in all lymph node: 102.2 -NUP98 NUP96 ENSG00000110713 Nucleoporin 98kDa 11 3671083-3797792 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA074810 Supported Nucleoplasm
Vesicles Expressed in all testis: 150.1 -NDUFS8 CI-23k, TYKY ENSG00000110717 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 11 68030617-68036644 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018524 Approved Supported Mitochondria Expressed in all adrenal gland: 153.3 -TCIRG1 a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7 ENSG00000110719 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 11 68039016-68050895 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038742 Approved Approved Mitochondria Expressed in all spleen: 83.5 -CHKA CHK, CKI ENSG00000110721 Choline kinase alpha 11 68052859-68121444 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024153, CAB072803 Approved Approved Endoplasmic reticulum Expressed in all testis: 135.2 -EXPH5 SLAC2-B ENSG00000110723 Exophilin 5 11 108505431-108593738 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skin: 31.3 parathyroid gland: 15.9 -HPS5 BLOC2S2 ENSG00000110756 Hermansky-Pudlak syndrome 5 11 18278668-18322198 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 39.7 -GTF2H1 BTF2, P62, TFIIH ENSG00000110768 General transcription factor IIH, polypeptide 1, 62kDa 11 18322295-18367044 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004637, HPA046660 Supported Validated Nucleoplasm Expressed in all testis: 60.0 -POU2AF1 OBF1 ENSG00000110777 POU class 2 associating factor 1 11 111352252-111455630 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB011193 Approved Tissue enhanced 0 lymph node: 103.0;tonsil: 97.6 appendix: 57.6 -PTPN5 PTPSTEP, STEP ENSG00000110786 Protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) 11 18727928-18792721 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031014, HPA072091 Supported Approved Endoplasmic reticulum Tissue enriched 15 cerebral cortex: 58.9 testis: 3.8 -VWF F8VWF ENSG00000110799 Von Willebrand factor 12 5948874-6124770 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001694, HPA001815, HPA002082, CAB072874, CAB072875 Supported Mixed adipose tissue: 154.4 -PSMD9 p27, Rpn4 ENSG00000110801 Proteasome 26S subunit, non-ATPase 9 12 121888731-121918297 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040512, HPA044220 Supported Supported Plasma membrane
Cytosol Expressed in all adipose tissue: 17.9 -P3H3 GRCB, HSU47926, LEPREL2 ENSG00000110811 Prolyl 3-hydroxylase 3 12 6828410-6839851 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043695 Approved Tissue enhanced 0 parathyroid gland: 11.5 endometrium: 6.2 -PPFIBP1 hSGT2, hSgt2p, L2, SGT2 ENSG00000110841 PTPRF interacting protein, binding protein 1 (liprin beta 1) 12 27523431-27695564 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001924 Uncertain Approved Plasma membrane
Cytosol Expressed in all ovary: 106.2 -PRPF40B HYPC ENSG00000110844 PRP40 homolog, pre-mRNA processing factor B 12 49568218-49644666 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038426, HPA038599 Approved Approved Nucleoplasm
Nuclear bodies
Aggresome
Cytosol Mixed testis: 39.2 -CD69 CLEC2C ENSG00000110848 CD69 molecule 12 9752486-9760901 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002503, HPA050525 Supported Tissue enhanced 0 bone marrow: 106.2;lymph node: 110.6 appendix: 66.2 -PRDM4 PFM1 ENSG00000110851 PR domain containing 4 12 107732866-107761272 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA024322, HPA067437 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 88.4 -CLEC2B AICL, CLECSF2, HP10085 ENSG00000110852 C-type lectin domain family 2, member B 12 9852984-9870136 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA008194 Approved Mixed skin: 87.3 -COQ5 MGC4767 ENSG00000110871 Coenzyme Q5, methyltransferase 12 120503274-120534434 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049487 Approved Approved Nucleoli
Mitochondria Expressed in all thyroid gland: 42.0 -SELPLG CD162, PSGL-1 ENSG00000110876 Selectin P ligand 12 108622277-108633959 Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002431 Supported Mixed spleen: 86.7 -CORO1C coronin-3, HCRNN4 ENSG00000110880 Coronin, actin binding protein, 1C 12 108645109-108731596 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041737 Approved Expressed in all smooth muscle: 206.2 -ASIC1 ACCN2, BNaC2, hBNaC2 ENSG00000110881 Acid sensing (proton gated) ion channel 1 12 50057548-50083611 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058870 Approved Golgi apparatus
Plasma membrane Tissue enriched 10 cerebral cortex: 57.0 parathyroid gland: 5.5 -DAO DAMOX ENSG00000110887 D-amino-acid oxidase 12 108858932-108901043 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038653, HPA038654 Supported Group enriched 36 kidney: 89.2;liver: 73.8 rectum: 2.2 -CAPRIN2 C1QDC1, caprin-2, EEG1, FLJ11391, FLJ22569, RNG140 ENSG00000110888 Caprin family member 2 12 30709552-30754951 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039746 Supported Supported Nucleus
Centrosome
Cytosol Mixed testis: 32.7 -TSPAN11 ENSG00000110900 Tetraspanin 11 12 30926428-30996599 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA066789 Approved Vesicles Mixed cerebral cortex: 18.0 -KCTD10 BTBD28, MSTP028 ENSG00000110906 Potassium channel tetramerization domain containing 10 12 109448656-109477544 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014273 Approved Supported Nucleoplasm
Cytosol Expressed in all smooth muscle: 78.7 -SLC11A2 DCT1, DMT1, NRAMP2 ENSG00000110911 Solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 12 50979401-51028566 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032139, HPA032140 Uncertain Supported Mitochondria Expressed in all thyroid gland: 74.8 -MLEC KIAA0152 ENSG00000110917 Malectin 12 120686869-120701864 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 161.6 -MVK LRBP, MK ENSG00000110921 Mevalonate kinase 12 109573255-109598117 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016961 Approved Expressed in all testis: 29.5 -CSRNP2 C12ORF2, C12orf22, FAM130A1, PPP1R72, TAIP-12 ENSG00000110925 Cysteine-serine-rich nuclear protein 2 12 51061205-51083664 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018503, HPA019914 Approved Approved Nuclear speckles Expressed in all testis: 49.1 -CAMKK2 CAMKK, CAMKKB, KIAA0787, MGC15254 ENSG00000110931 Calcium/calmodulin-dependent protein kinase kinase 2, beta 12 121237691-121298308 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017389 Approved Supported Cytosol Expressed in all cerebral cortex: 103.1 -BIN2 BRAP-1 ENSG00000110934 Bridging integrator 2 12 51281038-51324668 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038666, HPA038667 Supported Tissue enhanced 0 bone marrow: 65.9 spleen: 53.9 -IL23A IL-23, IL-23A, IL23P19, P19, SGRF ENSG00000110944 Interleukin 23, alpha subunit p19 12 56334174-56340410 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA001554 Approved Approved Cytosol Tissue enhanced 0 tonsil: 8.5 urinary bladder: 6.8 -ATP5B ATPSB ENSG00000110955 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 12 56638175-56646068 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001520, HPA001528, CAB017527 Supported Validated Mitochondria Expressed in all heart muscle: 1257.9 -PTGES3 cPGES, p23, TEBP ENSG00000110958 Prostaglandin E synthase 3 (cytosolic) 12 56663341-56688408 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034319, HPA038672, HPA038673 Approved Supported Nucleoplasm
Cytosol Expressed in all fallopian tube: 344.4 -SYT10 ENSG00000110975 Synaptotagmin X 12 33374238-33439819 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055426 Uncertain Approved Nucleoplasm
Vesicles Tissue enhanced 0 fallopian tube: 3.5 seminal vesicle: 1.1 -BCL7A BCL7 ENSG00000110987 B-cell CLL/lymphoma 7A 12 122019422-122062044 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019762 Approved Approved Nucleoplasm
Vesicles Expressed in all cerebral cortex: 13.8 -RSRC2 FLJ11021 ENSG00000111011 Arginine/serine-rich coiled-coil 2 12 122503458-122527000 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040070, HPA048183 Uncertain Validated Nucleoli fibrillar center
Nuclear speckles
Cytosol Expressed in all bone marrow: 42.6 -CYP27B1 CYP1, P450c1, PDDR, VDD1 ENSG00000111012 Cytochrome P450, family 27, subfamily B, polypeptide 1 12 57762334-57768986 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 kidney: 4.7;thyroid gland: 4.1 appendix: 1.3 -MYF6 bHLHc4, MRF4 ENSG00000111046 Myogenic factor 6 (herculin) 12 80707498-80709474 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 18 skeletal muscle: 99.2 esophagus: 5.3 -MYF5 bHLHc2 ENSG00000111049 Myogenic factor 5 12 80716912-80719673 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA041691 Supported Nucleoplasm Tissue enhanced 0 skeletal muscle: 1.9 prostate: 0.3 -LIN7A LIN-7A, MALS-1, TIP-33, VELI1 ENSG00000111052 Lin-7 homolog A (C. elegans) 12 80792520-80937925 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed bone marrow: 17.9 -KRT18 ENSG00000111057 Keratin 18, type I 12 52948871-52952901 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000008, CAB000030, HPA001605 Supported Validated Cytosol Mixed placenta: 654.2 -ACSS3 FLJ21963 ENSG00000111058 Acyl-CoA synthetase short-chain family member 3 12 80936414-81261205 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039353, HPA047956, HPA061517 Approved Approved Mitochondria Mixed parathyroid gland: 33.0 -TNS2 C1-TEN, KIAA1075, TENC1 ENSG00000111077 Tensin 2 12 53046969-53064372 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034659 Approved Mixed adipose tissue: 114.3 -GLI1 GLI ENSG00000111087 GLI family zinc finger 1 12 57460135-57472262 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009460, HPA065172 Uncertain Supported Nucleoplasm
Cytosol Tissue enhanced 0 cervix, uterine: 15.0;endometrium: 15.1 gallbladder: 8.5 -PPM1H ARHCL1, FLJ13253, KIAA1157, NERPP-2C ENSG00000111110 Protein phosphatase, Mg2+/Mn2+ dependent, 1H 12 62643982-62935037 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020694, HPA044244, HPA058777 Uncertain Supported Nucleoplasm Tissue enhanced 0 parathyroid gland: 53.3 cerebral cortex: 23.1 -METAP2 MAP2, MNPEP, p67 ENSG00000111142 Methionyl aminopeptidase 2 12 95473520-95515839 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013025, HPA019095 Supported Supported Plasma membrane
Cytosol Expressed in all seminal vesicle: 141.9 -LTA4H ENSG00000111144 Leukotriene A4 hydrolase 12 96000828-96043520 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008399, CAB015221, HPA017017 Supported Supported Nucleoplasm
Cytosol Expressed in all lung: 283.6 -ELK3 ERP, NET, SAP2 ENSG00000111145 ELK3, ETS-domain protein (SRF accessory protein 2) 12 96194382-96269835 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001600 Approved Supported Nucleoplasm
Mitochondria Expressed in all spleen: 58.6 -SLC6A12 BGT-1 ENSG00000111181 Solute carrier family 6 (neurotransmitter transporter), member 12 12 190077-214570 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034973, HPA057917 Approved Approved Golgi apparatus Tissue enhanced 0 kidney: 29.4;liver: 43.6 cerebral cortex: 14.8 -WNT5B ENSG00000111186 Wingless-type MMTV integration site family, member 5B 12 1529891-1647243 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA061991 Approved Vesicles Tissue enhanced 0 prostate: 33.3 seminal vesicle: 27.6 -MAGOHB FLJ10292, MGN2 ENSG00000111196 Mago homolog B, exon junction complex core component 12 10604190-10613623 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043036, HPA047754 Uncertain Mixed epididymis: 14.0 -TRPV4 CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC ENSG00000111199 Transient receptor potential cation channel, subfamily V, member 4 12 109783085-109833401 Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007150 Uncertain Mixed kidney: 11.8 -ITFG2 MDS028 ENSG00000111203 Integrin alpha FG-GAP repeat containing 2 12 2812622-2859791 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038664, HPA038665 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Cytokinetic bridge Expressed in all thyroid gland: 45.8 -FOXM1 FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident ENSG00000111206 Forkhead box M1 12 2857681-2877155 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017832, HPA029974 Uncertain Supported Nucleus
Nucleoli
Cytosol Tissue enhanced 0 testis: 39.5 bone marrow: 15.9 -PRR4 LPRP, PROL4 ENSG00000111215 Proline rich 4 (lacrimal) 12 10845849-11171613 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042133 Supported Uncertain Vesicles Tissue enriched 23 salivary gland: 1536.8 stomach: 66.9 -PRMT8 HRMT1L3, HRMT1L4 ENSG00000111218 Protein arginine methyltransferase 8 12 3381349-3593973 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039747, HPA069769 Approved Tissue enriched 8 cerebral cortex: 20.0 testis: 2.4 -PARP11 C12orf6 ENSG00000111224 Poly (ADP-ribose) polymerase family, member 11 12 3791047-3873448 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA026895 Uncertain Mixed testis: 17.6 -ARPC3 ARC21, p21-Arc ENSG00000111229 Actin related protein 2/3 complex, subunit 3, 21kDa 12 110434825-110450422 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006550 Approved Uncertain Nucleoplasm Expressed in all lymph node: 616.5 -GPN3 ATPBD1C, MGC14560 ENSG00000111231 GPN-loop GTPase 3 12 110452484-110469268 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039764, HPA047793 Uncertain Approved Nuclear speckles
Cytosol Expressed in all testis: 73.9 -VPS29 DC15, DC7, PEP11 ENSG00000111237 VPS29 retromer complex component 12 110491097-110502117 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039748 Uncertain Supported Vesicles
Cytosol Expressed in all epididymis: 107.2 -FGF6 ENSG00000111241 Fibroblast growth factor 6 12 4428155-4445614 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 8 skeletal muscle: 5.6 esophagus: 0.7 -MYL2 CMH10 ENSG00000111245 Myosin, light chain 2, regulatory, cardiac, slow 12 110910819-110920722 Candidate cardiovascular disease genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019763, HPA039262 Supported Uncertain Microtubules Group enriched 32 heart muscle: 13057.5;skeletal muscle: 9734.2 esophagus: 359.2 -RAD51AP1 PIR51 ENSG00000111247 RAD51 associated protein 1 12 4538798-4560048 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051499 Approved Nucleus Mixed testis: 11.5 -CUX2 CDP2, CUTL2, KIAA0293 ENSG00000111249 Cut-like homeobox 2 12 111034024-111350554 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044772 Uncertain Tissue enhanced 0 cerebral cortex: 12.2;liver: 9.6;prostate: 17.1 thyroid gland: 6.8 -SH2B3 IDDM20, LNK ENSG00000111252 SH2B adaptor protein 3 12 111405948-111451623 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005483 Approved Approved Nucleoplasm Expressed in all spleen: 51.9 -AKAP3 AKAP110, CT82, FSP95, SOB1 ENSG00000111254 A kinase (PRKA) anchor protein 3 12 4615508-4649047 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039765 Supported Tissue enriched 45 testis: 179.0 fallopian tube: 3.9 -MANSC1 FLJ10298, LOH12CR3 ENSG00000111261 MANSC domain containing 1 12 12326056-12350541 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA007955, HPA007956 Approved Approved Golgi apparatus
Vesicles Mixed parathyroid gland: 24.2 -KCNA1 AEMK, HUK1, Kv1.1, MBK1, RBK1 ENSG00000111262 Potassium channel, voltage gated shaker related subfamily A, member 1 12 4909905-4931361 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022365 Uncertain Tissue enriched 6 cerebral cortex: 13.5 parathyroid gland: 2.0 -DUSP16 KIAA1700, MKP-7, MKP7 ENSG00000111266 Dual specificity phosphatase 16 12 12474210-12562383 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020326 Approved Supported Nucleoplasm Expressed in all adrenal gland: 33.4 -CREBL2 ENSG00000111269 CAMP responsive element binding protein-like 2 12 12611827-12645108 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA043738 Uncertain Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all adrenal gland: 174.3 -ACAD10 MGC5601 ENSG00000111271 Acyl-CoA dehydrogenase family, member 10 12 111686056-111757107 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067222 Uncertain Expressed in all parathyroid gland: 33.5 -ALDH2 ENSG00000111275 Aldehyde dehydrogenase 2 family (mitochondrial) 12 111766887-111817529 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051065 Approved Expressed in all liver: 440.7 -CDKN1B KIP1, P27KIP1 ENSG00000111276 Cyclin-dependent kinase inhibitor 1B (p27, Kip1) 12 12715058-12722371 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003691, CAB021888, HPA059086 Approved Supported Nucleus
Vesicles Expressed in all ovary: 72.9 -GPRC5D ENSG00000111291 G protein-coupled receptor, class C, group 5, member D 12 12940775-12952147 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA071909 Approved Mixed testis: 5.2 -NAA25 C12orf30, FLJ13089 ENSG00000111300 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 12 112026689-112109022 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039322 Approved Supported Golgi apparatus
Cytosol Expressed in all parathyroid gland: 9.4 -GSG1 MGC3146 ENSG00000111305 Germ cell associated 1 12 13083560-13103683 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 364 testis: 571.3 duodenum: 1.5 -SCNN1A ENaCalpha, SCNN1 ENSG00000111319 Sodium channel, non voltage gated 1 alpha subunit 12 6346843-6377730 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA012743 Supported Mixed cervix: 94.4 -LTBR D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3 ENSG00000111321 Lymphotoxin beta receptor (TNFR superfamily, member 3) 12 6375045-6391571 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB026202 Uncertain Approved Golgi apparatus Expressed in all smooth muscle: 88.1 -OGFOD2 FLJ13491, FLJ37501 ENSG00000111325 2-oxoglutarate and iron-dependent oxygenase domain containing 2 12 122974580-122980043 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039448, HPA040306 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 23.0 -CDK2AP1 doc-1, DOC1, DORC1, p12DOC-1, ST19 ENSG00000111328 Cyclin-dependent kinase 2 associated protein 1 12 123260971-123272334 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019377, HPA057648, HPA068833 Approved Validated Nucleoplasm Expressed in all cerebral cortex: 294.8 -OAS3 ENSG00000111331 2'-5'-oligoadenylate synthetase 3, 100kDa 12 112938352-112973249 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041253, HPA041372 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Mixed spleen: 34.0 -OAS2 ENSG00000111335 2'-5'-oligoadenylate synthetase 2, 69/71kDa 12 112978395-113011723 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB024984, HPA045947 Approved Approved Nucleoplasm
Cytosol Mixed spleen: 60.8 -ART4 CD297, DO, DOK1 ENSG00000111339 ADP-ribosyltransferase 4 (Dombrock blood group) 12 14825569-14843495 Blood group antigen proteins, CD markers, Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA075664 Uncertain Rods & Rings Tissue enhanced 0 liver: 27.1;spleen: 27.3 gallbladder: 15.2 -MGP ENSG00000111341 Matrix Gla protein 12 14881181-14885926 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013949 Uncertain Tissue enhanced 0 breast: 4805.9 smooth muscle: 1875.4 -RASAL1 RASAL ENSG00000111344 RAS protein activator like 1 (GAP1 like) 12 113098819-113136239 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041650 Uncertain Approved Plasma membrane
Cell Junctions
Cytosol Tissue enriched 6 parathyroid gland: 116.7 cerebral cortex: 19.5 -ARHGDIB GDIA2, GDID4, Ly-GDI, RAP1GN1, RhoGDI2 ENSG00000111348 Rho GDP dissociation inhibitor (GDI) beta 12 14942017-14961728 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018584, HPA051235 Approved Supported Cytosol Expressed in all lymph node: 968.2 -GTF2H3 BTF2, P34, TFIIH ENSG00000111358 General transcription factor IIH, polypeptide 3, 34kDa 12 123633739-123662606 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004844, HPA053562 Uncertain Supported Nucleoplasm Expressed in all cerebral cortex: 26.7 -EIF2B1 EIF-2B, EIF-2Balpha, EIF2B, EIF2BA ENSG00000111361 Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 12 123620406-123633766 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034258, HPA049509 Approved Supported Cytosol Expressed in all skin: 59.4 -DDX55 KIAA1595 ENSG00000111364 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 12 123602077-123620941 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039962, HPA044101 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all skin: 16.5 -SLC38A1 ATA1, NAT2, SAT1 ENSG00000111371 Solute carrier family 38, member 1 12 46183063-46270017 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039460, HPA052272 Uncertain Supported Expressed in all parathyroid gland: 153.2 -RERGL FLJ22655 ENSG00000111404 RERG/RAS-like 12 18080869-18320107 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA041740 Uncertain Mixed epididymis: 46.1 -ENDOU P11, PP11, PRSS26 ENSG00000111405 Endonuclease, polyU-specific 12 47709734-47725567 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012388, HPA067448 Supported Group enriched 6 esophagus: 70.6;skin: 24.9 tonsil: 8.1 -C12orf49 FLJ21415 ENSG00000111412 Chromosome 12 open reading frame 49 12 116710185-116738070 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026905 Uncertain Tissue enhanced 0 thyroid gland: 62.3 lung: 28.1 -VDR NR1I1, PPP1R163 ENSG00000111424 Vitamin D (1,25- dihydroxyvitamin D3) receptor 12 47841537-47943048 Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004617, HPA047740 Validated Nucleoplasm Tissue enhanced 0 parathyroid gland: 172.8 small intestine: 59.2 -FZD10 CD350 ENSG00000111432 Frizzled class receptor 10 12 130162459-130165740 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA014484, HPA014485 Uncertain Supported Nucleoplasm Tissue enhanced 0 cervix, uterine: 9.3;esophagus: 8.8 skin: 5.6 -RFC5 RFC36 ENSG00000111445 Replication factor C (activator 1) 5, 36.5kDa 12 118013588-118033130 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041037 Supported Approved Nucleoplasm Expressed in all bone marrow: 22.2 -STX2 EPIM, EPM, STX2A, STX2B, STX2C ENSG00000111450 Syntaxin 2 12 130789600-130839266 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038189, HPA069176 Uncertain Approved Nucleus
Cytosol Expressed in all testis: 35.1 -ADGRD1 DKFZp434B1272, GPR133, PGR25 ENSG00000111452 Adhesion G protein-coupled receptor D1 12 130953907-131141469 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042395 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 placenta: 44.3 lung: 32.7 -COPZ1 CGI-120, COPZ ENSG00000111481 Coatomer protein complex, subunit zeta 1 12 54301202-54351849 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 191.8 -TBC1D30 KIAA0984 ENSG00000111490 TBC1 domain family, member 30 12 64781193-64881032 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039772, HPA040043 Approved Approved Plasma membrane
Cytosol Mixed parathyroid gland: 12.3 -CAND1 DKFZp434M1414, KIAA0829, TIP120, TIP120A ENSG00000111530 Cullin-associated and neddylation-dissociated 1 12 67269281-67319951 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055748, HPA062833, HPA069053 Approved Validated Nucleoplasm
Golgi apparatus
Cytosol Expressed in all testis: 50.9 -IL26 AK155, IL-26 ENSG00000111536 Interleukin 26 12 68201351-68225821 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 appendix: 1.2;tonsil: 1.1;urinary bladder: 1.4 lymph node: 0.3 -IFNG ENSG00000111537 Interferon, gamma 12 68154768-68159747 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB010344 Approved Tissue enhanced 0 appendix: 4.9;bone marrow: 7.6;lymph node: 8.0 lung: 2.5 -RAB5B ENSG00000111540 RAB5B, member RAS oncogene family 12 55973913-55996683 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010224, HPA068337 Approved Supported Vesicles Expressed in all parathyroid gland: 172.6 -MDM1 ENSG00000111554 Mdm1 nuclear protein 12 68272443-68332381 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040411, HPA041594 Uncertain Supported Centrosome
Cytosol Expressed in all testis: 37.3 -NUP107 NUP84 ENSG00000111581 Nucleoporin 107kDa 12 68686734-68745809 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024141, HPA031679 Uncertain Supported Nucleoplasm
Centrosome Expressed in all testis: 38.0 -CNOT2 CDC36, NOT2, NOT2H ENSG00000111596 CCR4-NOT transcription complex, subunit 2 12 70242994-70354993 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067711 Approved Approved Nucleus
Cytosol Expressed in all skin: 54.3 -TIMELESS hTIM, TIM, TIM1 ENSG00000111602 Timeless circadian clock 12 56416373-56449403 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060655 Supported Supported Nucleus Mixed lymph node: 18.5 -CPSF6 CFIM, CFIM68, HPBRII-4, HPBRII-7 ENSG00000111605 Cleavage and polyadenylation specific factor 6, 68kDa 12 69239537-69274358 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039973 Supported Validated Nucleoplasm
Nuclear speckles Expressed in all lymph node: 56.0 -KRR1 HRB2, RIP-1 ENSG00000111615 KRR1, small subunit (SSU) processome component, homolog (yeast) 12 75490861-75511636 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043433, HPA051690 Approved Validated Nucleus
Nucleoli Expressed in all bone marrow: 39.6 -MRPL51 bMRP64, CDA09, HSPC241, MRP64 ENSG00000111639 Mitochondrial ribosomal protein L51 12 6491886-6493841 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039923 Approved Supported Mitochondria Expressed in all testis: 233.5 -GAPDH GAPD ENSG00000111640 Glyceraldehyde-3-phosphate dehydrogenase 12 6533927-6538374 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005197, CAB016392, HPA040067, HPA061280 Supported Validated Plasma membrane
Cytosol Expressed in all skeletal muscle: 9875.4 -NOP2 NOL1, NOP120, NSUN1, p120 ENSG00000111641 NOP2 nucleolar protein 12 6556863-6568691 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040119 Supported Supported Nucleoli Expressed in all lymph node: 36.1 -CHD4 Mi-2b, Mi2-BETA ENSG00000111642 Chromodomain helicase DNA binding protein 4 12 6570083-6607476 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012008 Supported Validated Nucleus Expressed in all parathyroid gland: 117.2 -ACRBP CT23, OY-TES-1, SP32 ENSG00000111644 Acrosin binding protein 12 6638075-6647460 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039081, HPA039082 Supported Approved Nucleoplasm
Vesicles Tissue enriched 19 testis: 432.6 thyroid gland: 22.6 -UHRF1BP1L KIAA0701 ENSG00000111647 UHRF1 binding protein 1-like 12 100028455-100142848 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039671, HPA040399 Uncertain Approved Plasma membrane Mixed cerebral cortex: 33.0 -COPS7A CSN7A ENSG00000111652 COP9 signalosome subunit 7A 12 6723741-6731875 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026915 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 90.4 -ING4 my036, p29ING4 ENSG00000111653 Inhibitor of growth family, member 4 12 6650280-6663148 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031817, HPA057338 Approved Supported Nucleoplasm Expressed in all thyroid gland: 43.2 -GNB3 ENSG00000111664 Guanine nucleotide binding protein (G protein), beta polypeptide 3 12 6839954-6847393 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040736 Approved Uncertain Golgi apparatus
Plasma membrane Mixed smooth muscle: 3.7 -CDCA3 GRCC8, TOME-1 ENSG00000111665 Cell division cycle associated 3 12 6844793-6852066 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026587 Approved Cytosol Tissue enhanced 0 testis: 30.8 small intestine: 19.7 -CHPT1 CPT1 ENSG00000111666 Choline phosphotransferase 1 12 101696947-101744140 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067643 Approved Approved Vesicles Expressed in all breast: 124.5 -USP5 IsoT ENSG00000111667 Ubiquitin specific peptidase 5 (isopeptidase T) 12 6852128-6866632 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006756 Uncertain Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 87.6 -TPI1 ENSG00000111669 Triosephosphate isomerase 1 12 6867119-6870948 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050924, HPA053568 Uncertain Validated Nucleoplasm Expressed in all skeletal muscle: 942.9 -GNPTAB GNPTA, KIAA1208, MGC4170 ENSG00000111670 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 12 101745497-101830938 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017754, HPA042343 Approved Approved Vesicles Expressed in all parathyroid gland: 64.0 -SPSB2 GRCC9, SSB-2 ENSG00000111671 SplA/ryanodine receptor domain and SOCS box containing 2 12 6870935-6889358 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055225 Approved Expressed in all lung: 12.8 -ENO2 ENSG00000111674 Enolase 2 (gamma, neuronal) 12 6913745-6923698 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000063, HPA068284, CAB073539 Supported Approved Nucleus
Plasma membrane
Cytosol Tissue enriched 7 cerebral cortex: 432.2 parathyroid gland: 64.5 -ATN1 B37, D12S755E, DRPLA ENSG00000111676 Atrophin 1 12 6924463-6942321 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031619 Supported Validated Nucleoplasm Expressed in all ovary: 139.3 -C12orf57 C10, GRCC10 ENSG00000111678 Chromosome 12 open reading frame 57 12 6942978-6946003 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046182, HPA059163, HPA066043 Approved Supported Nuclear speckles Expressed in all ovary: 522.7 -PTPN6 HCP, HCPH, PTP-1C, SHP-1, SHP1 ENSG00000111679 Protein tyrosine phosphatase, non-receptor type 6 12 6946468-6961316 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001466, CAB004572, CAB072845 Supported Supported Nucleus
Nucleoli Mixed lymph node: 163.5 -LPCAT3 C3F, MBOAT5, nessy, OACT5 ENSG00000111684 Lysophosphatidylcholine acyltransferase 3 12 6976186-7018510 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all duodenum: 126.4 -NT5DC3 FLJ11266, TU12B1-TY ENSG00000111696 5'-nucleotidase domain containing 3 12 103770453-103841197 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041634 Approved Mitochondria
Cytosol Mixed endometrium: 15.9 -SLCO1B3 OATP1B3, OATP8, SLC21A8 ENSG00000111700 Solute carrier organic anion transporter family, member 1B3 12 20810702-20916911 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004943, HPA050892 Supported Supported Plasma membrane Tissue enriched 7 liver: 138.5 cervix: 19.4 -APOBEC1 APOBEC-1, BEDP, CDAR1, HEPR ENSG00000111701 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 12 7649400-7665903 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 21 duodenum: 32.8;small intestine: 31.7 stomach: 1.5 -NANOG FLJ12581, FLJ40451 ENSG00000111704 Nanog homeobox 12 7787794-7799141 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB019380 Supported Tissue enhanced 0 testis: 2.0 skin: 0.7 -SUDS3 FLJ00052, SAP45, SDS3 ENSG00000111707 SDS3 homolog, SIN3A corepressor complex component 12 118376380-118418031 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040402, HPA041972 Approved Supported Nuclear bodies
Cytosol Expressed in all parathyroid gland: 35.6 -GOLT1B CGI-141, GOT1, YMR292W ENSG00000111711 Golgi transport 1B 12 21501781-21518408 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055909, HPA066383 Approved Approved Vesicles Expressed in all placenta: 42.1 -GYS2 ENSG00000111713 Glycogen synthase 2 (liver) 12 21536189-21604847 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039482 Approved Tissue enriched 23 liver: 91.7 adipose tissue: 3.9 -LDHB ENSG00000111716 Lactate dehydrogenase B 12 21635342-21757857 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004641, HPA019007 Supported Validated Cytosol Expressed in all kidney: 1776.6 -PRKAB1 ENSG00000111725 Protein kinase, AMP-activated, beta 1 non-catalytic subunit 12 119667753-119681630 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004247, CAB005058 Supported Approved Nucleoplasm
Cytosol Expressed in all kidney: 53.7 -CMAS ENSG00000111726 Cytidine monophosphate N-acetylneuraminic acid synthetase 12 22046174-22065674 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039905 Supported Uncertain Nucleoli
Cytosol Expressed in all testis: 127.6 -HCFC2 HCF-2 ENSG00000111727 Host cell factor C2 12 104064457-104106524 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006227 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 17.0 -ST8SIA1 SIAT8, SIAT8A ENSG00000111728 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 12 22063773-22437041 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA026775 Approved Mixed cerebral cortex: 9.1 -CLEC4A CD367, CLECSF6, DCIR, DDB27 ENSG00000111729 C-type lectin domain family 4, member A 12 8123632-8138607 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007842 Uncertain Tissue enhanced 0 appendix: 38.2 spleen: 21.4 -C2CD5 CDP138, KIAA0528 ENSG00000111731 C2 calcium-dependent domain containing 5 12 22448583-22544546 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046194 Approved Approved Microtubule organizing center
Cytosol Expressed in all parathyroid gland: 50.8 -AICDA AID, ARP2, CDA2, HIGM2 ENSG00000111732 Activation-induced cytidine deaminase 12 8602166-8612871 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 11 appendix: 5.1;lymph node: 18.9;tonsil: 11.5 spleen: 1.0 -RAB35 H-ray ENSG00000111737 RAB35, member RAS oncogene family 12 120095095-120117502 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054146 Approved Expressed in all appendix: 39.1 -PHC1 EDR1, HPH1, RAE28 ENSG00000111752 Polyhomeotic homolog 1 (Drosophila) 12 8913896-8941467 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006973 Approved Supported Nucleus Expressed in all testis: 80.4 -COX6A1 COX6A ENSG00000111775 Cytochrome c oxidase subunit VIa polypeptide 1 12 120438090-120440742 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062394 Approved Supported Mitochondria Expressed in all duodenum: 589.3 -AL021546.6 ENSG00000111780 12 120438198-120460006 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA062394 Uncertain Approved Mitochondria Tissue enhanced 0 colon: 1.0 spleen: 0.6 -RFX4 ENSG00000111783 Regulatory factor X, 4 (influences HLA class II expression) 12 106582907-106762803 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050527 Supported Approved Nucleus Group enriched 184 cerebral cortex: 30.9;testis: 135.3 prostate: 0.4 -RIC8B FLJ10620, hSyn, RIC8 ENSG00000111785 RIC8 guanine nucleotide exchange factor B 12 106774595-106889316 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042746 Approved Approved Centrosome
Cytosol Mixed parathyroid gland: 21.3 -SRSF9 SFRS9, SRp30c ENSG00000111786 Serine/arginine-rich splicing factor 9 12 120461668-120469793 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049849 Supported Approved Nucleoplasm Expressed in all testis: 138.5 -FGFR1OP2 DKFZp564O1863 ENSG00000111790 FGFR1 oncogene partner 2 12 26938383-26966650 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038308, HPA038696 Supported Approved Mitochondria Expressed in all ovary: 73.6 -KLRB1 CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A ENSG00000111796 Killer cell lectin-like receptor subfamily B, member 1 12 9594551-9607886 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039113 Approved Uncertain Nucleoplasm
Cytosol Mixed spleen: 41.3 -COL12A1 COL12A1L ENSG00000111799 Collagen, type XII, alpha 1 6 75084326-75206051 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009143, HPA070695 Uncertain Approved Nucleus Mixed endometrium: 113.2 -BTN3A3 BTF3, BTN3.3 ENSG00000111801 Butyrophilin, subfamily 3, member A3 6 26440472-26453415 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007904, HPA011871 Supported Mixed spleen: 65.0 -TDP2 TTRAP ENSG00000111802 Tyrosyl-DNA phosphodiesterase 2 6 24649977-24667033 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB073398, HPA074011 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all small intestine: 193.0 -FRK GTK, PTK5, RAK ENSG00000111816 Fyn-related Src family tyrosine kinase 6 115931149-116060758 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025217, HPA057484 Approved Supported Nucleoplasm
Cytosol Mixed kidney: 10.4 -DSE DSEPI, SART2 ENSG00000111817 Dermatan sulfate epimerase 6 116254173-116444860 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014764, HPA052151 Uncertain Supported Nucleoplasm
Cytosol Mixed appendix: 37.1 -RWDD1 PTD013 ENSG00000111832 RWD domain containing 1 6 116571367-116597675 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028712, HPA028713 Approved Expressed in all adrenal gland: 62.0 -RSPH4A CILD11, dJ412I7.1, FLJ37974, RSHL3, RSPH6B ENSG00000111834 Radial spoke head 4 homolog A (Chlamydomonas) 6 116616479-116632985 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031196, HPA031197, HPA031198 Supported Supported Nucleus Tissue enriched 8 fallopian tube: 59.4 lung: 7.1 -MAK dJ417M14.2, RP62 ENSG00000111837 Male germ cell-associated kinase 6 10762723-10838555 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039092 Uncertain Group enriched 9 fallopian tube: 9.8;parathyroid gland: 10.3;testis: 20.3 lung: 1.5 -TMEM14C bA421M1.6, C6orf53, HSPC194, NET26 ENSG00000111843 Transmembrane protein 14C 6 10722915-10731129 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 138.2 -PAK1IP1 bA421M1.5, FLJ20624, hPIP1, MAK11, PIP1, WDR84 ENSG00000111845 PAK1 interacting protein 1 6 10694695-10709782 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030112 Supported Uncertain Nucleoplasm Expressed in all prostate: 109.0 -GCNT2 bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3 ENSG00000111846 Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 6 10492223-10629368 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026776 Approved Supported Golgi apparatus Tissue enhanced 0 prostate: 49.8 breast: 14.2 -SMIM8 C6orf162, dJ102H19.2, DKFZP586E1923 ENSG00000111850 Small integral membrane protein 8 6 87322583-87399749 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007401, HPA067453 Approved Approved Vesicles Mixed cerebral cortex: 14.0 -NEDD9 CAS-L, CASS2, HEF1 ENSG00000111859 Neural precursor cell expressed, developmentally down-regulated 9 6 11183298-11382348 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009720, HPA038768, HPA039270 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all lung: 109.7 -CEP85L bA57K17.2, C6orf204, NY-BR-15 ENSG00000111860 Centrosomal protein 85kDa-like 6 118460772-118710075 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029137, HPA029138, HPA029139 Uncertain Tissue enhanced 0 testis: 54.0 lymph node: 15.8 -ADTRP AIG1L, C6orf105, dJ413H6.1 ENSG00000111863 Androgen-dependent TFPI-regulating protein 6 11712054-11807046 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048113 Uncertain Uncertain Nucleoli Tissue enhanced 0 small intestine: 81.0 duodenum: 62.8 -ASF1A CIA, DKFZP547E2110 ENSG00000111875 Anti-silencing function 1A histone chaperone 6 118894220-118909167 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030502, HPA071495 Validated Nucleus Expressed in all parathyroid gland: 35.1 -MCM9 C6orf61, dJ329L24.3, FLJ20170, MCMDC1, MGC35304 ENSG00000111877 Minichromosome maintenance 9 homologous recombination repair factor 6 118813442-118935162 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031137 Approved Approved Nucleoplasm Mixed epididymis: 15.2 -FAM184A C6orf60, FLJ13942 ENSG00000111879 Family with sequence similarity 184, member A 6 118959763-119149387 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA034571, HPA034572, HPA041955 Uncertain Supported Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced 0 placenta: 45.6;testis: 45.0 cerebral cortex: 25.2 -RNGTT hCAP, HCE, HCE1 ENSG00000111880 RNA guanylyltransferase and 5'-phosphatase 6 88610272-88963721 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003750 Approved Approved Nucleoplasm Mixed lymph node: 21.3 -MAN1A1 ENSG00000111885 Mannosidase, alpha, class 1A, member 1 6 119177209-119349761 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037058, HPA053198, HPA063561 Uncertain Supported Golgi apparatus
Cytosol Expressed in all placenta: 111.4 -GABRR2 ENSG00000111886 Gamma-aminobutyric acid (GABA) A receptor, rho 2 6 89257208-89315299 FDA approved drug targets, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected lymph node: 0.1 -SERINC1 KIAA1253, TDE1L, TDE2, TMS-2 ENSG00000111897 Serine incorporator 1 6 122443354-122471822 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035738, HPA035739 Uncertain Approved Cytosol Expressed in all cerebral cortex: 617.2 -HDDC2 C6orf74, CGI-130, dJ167O5.2 ENSG00000111906 HD domain containing 2 6 125219962-125302078 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035677 Approved Approved Nucleus
Nucleoli Expressed in all testis: 116.6 -TPD52L1 D53, hD53 ENSG00000111907 Tumor protein D52-like 1 6 125119049-125264407 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027915, HPA027916 Approved Approved Plasma membrane
Cell Junctions
Cytosol Tissue enhanced 0 adrenal gland: 321.3 salivary gland: 126.8 -HINT3 FLJ33126 ENSG00000111911 Histidine triad nucleotide binding protein 3 6 125956781-125980244 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027914 Approved Supported Nucleoli
Mitochondria
Cytosol Expressed in all cerebral cortex: 49.8 -NCOA7 dJ187J11.3, ERAP140, TLDC4 ENSG00000111912 Nuclear receptor coactivator 7 6 125781161-125932030 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030289, HPA030290, HPA030291, HPA030292 Approved Approved Nuclear bodies
Golgi apparatus Expressed in all urinary bladder: 91.4 -FAM65B C6orf32, DIFF48, KIAA0386, MYONAP ENSG00000111913 Family with sequence similarity 65, member B 6 24804282-25042168 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lymph node: 92.4 spleen: 73.0 -SASH1 dJ323M4.1, KIAA0790, SH3D6A ENSG00000111961 SAM and SH3 domain containing 1 6 148272304-148552050 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029947, HPA029949 Uncertain Approved Nucleoplasm
Cytosol Mixed thyroid gland: 60.8 -UST 2OST ENSG00000111962 Uronyl-2-sulfotransferase 6 148747328-149076990 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA032022 Approved Approved Mitochondria Tissue enhanced 0 thyroid gland: 49.6 adrenal gland: 17.0 -ULBP1 RAET1I ENSG00000111981 UL16 binding protein 1 6 149964007-149973710 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA007547, HPA071005 Supported Approved Plasma membrane
Actin filaments
Cytosol Tissue enhanced 0 testis: 11.0 thyroid gland: 3.5 -FBXO5 EMI1, FBX5, Fbxo31 ENSG00000112029 F-box protein 5 6 152970519-152983579 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008106, HPA029048 Approved Supported Nucleoplasm Mixed bone marrow: 27.2 -MTRF1L ENSG00000112031 Mitochondrial translational release factor 1-like 6 152987362-153002685 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036367 Uncertain Expressed in all thyroid gland: 13.2 -PPARD FAAR, NR1C2, NUC1, NUCII ENSG00000112033 Peroxisome proliferator-activated receptor delta 6 35342558-35428191 FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level CAB017635 Approved Expressed in all placenta: 40.1 -OPRM1 MOR1 ENSG00000112038 Opioid receptor, mu 1 6 154010496-154246867 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA014509, HPA067435 Supported Supported Tissue enhanced 0 testis: 4.2 esophagus: 1.2 -FANCE FACE, FAE ENSG00000112039 Fanconi anemia, complementation group E 6 35452361-35467103 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB014893 Supported Supported Nucleoplasm Mixed skin: 16.2 -TULP1 LCA15, RP14, TUBL1 ENSG00000112041 Tubby like protein 1 6 35497874-35512938 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB070416 Uncertain Not detected prostate: 0.7 -SLC26A8 ENSG00000112053 Solute carrier family 26 (anion exchanger), member 8 6 35943514-36024868 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038080, HPA038081 Uncertain Tissue enriched 27 testis: 75.6 bone marrow: 2.8 -MAPK14 CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15 ENSG00000112062 Mitogen-activated protein kinase 14 6 36027677-36111236 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010285, CAB040578, HPA051825 Approved Supported Nuclear speckles Expressed in all placenta: 62.7 -RHAG CD241, RH50A, SLC42A1 ENSG00000112077 Rh-associated glycoprotein 6 49605158-49636839 CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055331 Approved Tissue enriched 24 bone marrow: 73.8 placenta: 3.0 -KCTD20 C6orf69, dJ108K11.3, MGC14254 ENSG00000112078 Potassium channel tetramerization domain containing 20 6 36442767-36491143 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030092 Approved Approved Nuclear speckles
Endoplasmic reticulum Expressed in all adipose tissue: 46.7 -STK38 NDR ENSG00000112079 Serine/threonine kinase 38 6 36493892-36547470 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004673, HPA038623, HPA051324 Uncertain Approved Cytosol Expressed in all rectum: 40.9 -SRSF3 SFRS3, SRp20 ENSG00000112081 Serine/arginine-rich splicing factor 3 6 36594353-36605600 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012986, HPA056981 Supported Supported Nucleoplasm Expressed in all lymph node: 141.5 -SOD2 ENSG00000112096 Superoxide dismutase 2, mitochondrial 6 159669057-159762529 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001814, CAB002013 Supported Expressed in all appendix: 750.9 -MRPL18 HSPC071 ENSG00000112110 Mitochondrial ribosomal protein L18 6 159789812-159798436 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028774, HPA028775 Approved Expressed in all fallopian tube: 84.9 -IL17A CTLA8, IL-17, IL-17A, IL17 ENSG00000112115 Interleukin 17A 6 52186387-52190638 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052258 Uncertain Tissue enhanced 0 appendix: 1.0;tonsil: 1.4;urinary bladder: 1.6 gallbladder: 0.3 -IL17F IL-17F, ML-1, ML1 ENSG00000112116 Interleukin 17F 6 52236681-52244537 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 tonsil: 1.9 urinary bladder: 0.9 -MCM3 ENSG00000112118 Minichromosome maintenance complex component 3 6 52264009-52284881 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002162, HPA004789, HPA004790 Supported Validated Nucleoplasm Expressed in all lymph node: 81.8 -RNF8 KIAA0646 ENSG00000112130 Ring finger protein 8, E3 ubiquitin protein ligase 6 37353972-37394738 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050731, HPA064925 Approved Supported Nucleus
Cytosol Mixed testis: 18.4 -PHACTR1 dJ257A7.2, KIAA1733, RPEL1 ENSG00000112137 Phosphatase and actin regulator 1 6 12716805-13290484 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029755, HPA029756, HPA029757 Supported Uncertain Plasma membrane Tissue enhanced 0 cerebral cortex: 27.9 bone marrow: 15.6 -MDGA1 GPIM, MAMDC3 ENSG00000112139 MAM domain containing glycosylphosphatidylinositol anchor 1 6 37630679-37699306 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031235, HPA050382 Approved Supported Golgi apparatus
Plasma membrane Mixed parathyroid gland: 10.5 -ICK KIAA0936, LCK2, MGC46090, MRK ENSG00000112144 Intestinal cell (MAK-like) kinase 6 53001279-53061802 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA001113 Approved Mixed adrenal gland: 23.2 -FBXO9 FBX9, NY-REN-57 ENSG00000112146 F-box protein 9 6 53051991-53100873 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064246 Approved Centrosome Expressed in all adrenal gland: 108.0 -CD83 BL11, HB15 ENSG00000112149 CD83 molecule 6 14117256-14136918 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB002509, HPA041454 Supported Approved Vesicles Tissue enhanced 0 bone marrow: 131.1 tonsil: 66.5 -MDN1 KIAA0301, Rea1 ENSG00000112159 Midasin AAA ATPase 1 6 89642499-89819723 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029666, HPA029667, HPA029668, HPA029669 Uncertain Approved Nucleus
Nucleoli
Intermediate filaments
Cytosol Mixed parathyroid gland: 13.3 -GLP1R ENSG00000112164 Glucagon-like peptide 1 receptor 6 39048798-39087743 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 1.9;heart muscle: 1.8 pancreas: 1.5 -SAYSD1 C6orf64, FLJ11101 ENSG00000112167 SAYSVFN motif domain containing 1 6 39104064-39115189 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA007959 Approved Validated Vesicles Tissue enriched 6 testis: 85.5 prostate: 14.9 -BMP5 ENSG00000112175 Bone morphogenetic protein 5 6 55753645-55875564 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 5 placenta: 101.7 prostate: 20.2 -BACH2 BTBD25 ENSG00000112182 BTB and CNC homology 1, basic leucine zipper transcription factor 2 6 89926529-90296908 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051384, HPA058384 Supported Supported Nucleus
Cytosol Tissue enhanced 0 lymph node: 21.4 tonsil: 12.5 -RBM24 dJ259A10.1, FLJ30829, RNPC6 ENSG00000112183 RNA binding motif protein 24 6 17281346-17293875 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA066927, HPA067231 Validated Nucleoplasm
Cytosol Tissue enhanced 0 heart muscle: 94.7;skeletal muscle: 109.8 endometrium: 51.3 -CAP2 ENSG00000112186 CAP, adenylate cyclase-associated protein, 2 (yeast) 6 17393216-17557792 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050530, HPA054147 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 125.5;skeletal muscle: 220.9 heart muscle: 69.1 -TREML2 C6orf76, dJ238O23.1, FLJ13693, TLT2 ENSG00000112195 Triggering receptor expressed on myeloid cells-like 2 6 41190277-41201194 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 9.5;bone marrow: 10.0;lymph node: 12.0 spleen: 8.9 -ZNF451 COASTER, dJ417I1.1, KIAA0576, KIAA1702 ENSG00000112200 Zinc finger protein 451 6 57086844-57170307 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028838 Approved Nucleus Expressed in all testis: 50.1 -BAG2 ENSG00000112208 BCL2-associated athanogene 2 6 57172326-57189833 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018862, HPA019918 Approved Supported Nucleoplasm Tissue enhanced 0 smooth muscle: 47.9 endometrium: 40.2 -RAB23 ENSG00000112210 RAB23, member RAS oncogene family 6 57186992-57222314 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029135, HPA029136 Approved Validated Plasma membrane
Cytosol Mixed smooth muscle: 101.8 -TSPO2 BZRPL1, dJ34B21.2 ENSG00000112212 Translocator protein 2 6 41042554-41044337 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA066996 Uncertain Tissue enriched 16 bone marrow: 30.9 placenta: 1.8 -FHL5 ACT, dJ393D12.2, FLJ33049 ENSG00000112214 Four and a half LIM domains 5 6 96562548-96616636 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 testis: 105.8 cervix: 43.1 -GPR63 PSP24(beta), PSP24B ENSG00000112218 G protein-coupled receptor 63 6 96794126-96837463 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039103 Approved Approved Nucleus
Plasma membrane
Cytosol Mixed testis: 4.6 -KHDRBS2 MGC26664, SLM-1, SLM1 ENSG00000112232 KH domain containing, RNA binding, signal transduction associated 2 6 61679960-62286227 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000500, HPA029392 Supported Tissue enhanced 0 cerebral cortex: 6.7;lung: 5.6;thyroid gland: 10.9 spleen: 1.9 -FBXL4 FBL4, FBL5 ENSG00000112234 F-box and leucine-rich repeat protein 4 6 98868538-98948006 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029140, CAB033362 Approved Supported Nuclear speckles Expressed in all parathyroid gland: 24.8 -CCNC CycC ENSG00000112237 Cyclin C 6 99542380-99568973 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010499, HPA069322 Uncertain Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 99.7 -PRDM13 ENSG00000112238 PR domain containing 13 6 99606730-99615578 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA070592 Uncertain Not detected epididymis: 0.0 -E2F3 ENSG00000112242 E2F transcription factor 3 6 20401906-20493715 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065012 Supported Nucleoplasm
Cytosol Mixed thyroid gland: 14.3 -PTP4A1 PRL-1, PTPCAAX1 ENSG00000112245 Protein tyrosine phosphatase type IVA, member 1 6 63521761-63583587 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003281 Approved Expressed in all liver: 354.2 -SIM1 bHLHe14 ENSG00000112246 Single-minded family bHLH transcription factor 1 6 100385015-100464929 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA024385 Approved Nuclear speckles Tissue enhanced 0 epididymis: 3.4;kidney: 11.1;seminal vesicle: 3.1 skeletal muscle: 1.2 -ASCC3 ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH ENSG00000112249 Activating signal cointegrator 1 complex subunit 3 6 100508194-100881372 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031608, HPA031609, HPA031610 Approved Supported Golgi apparatus
Cytosol Expressed in all parathyroid gland: 26.0 -HDGFL1 dJ309H15.1, PWWP1 ENSG00000112273 Hepatoma derived growth factor-like 1 6 22569493-22571666 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045679, HPA063707 Supported Tissue enriched 1391 testis: 139.0 epididymis: 0.0 -BVES HBVES, POP1, POPDC1 ENSG00000112276 Blood vessel epicardial substance 6 105096822-105137174 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014788, HPA018176 Supported Supported Cell Junctions Tissue enhanced 0 smooth muscle: 24.7 testis: 20.7 -COL9A1 ENSG00000112280 Collagen, type IX, alpha 1 6 70215061-70303083 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 prostate: 32.7 testis: 5.0 -MED23 CRSP130, CRSP3, DRIP130, Sur2 ENSG00000112282 Mediator complex subunit 23 6 131573966-131628229 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070341 Approved Nucleoplasm
Vesicles Expressed in all parathyroid gland: 31.6 -WASF1 KIAA0269, SCAR1, WAVE, WAVE1 ENSG00000112290 WAS protein family, member 1 6 110099819-110180004 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004105, CAB022161 Approved Approved Group enriched 5 cerebral cortex: 139.4;testis: 149.1 ovary: 27.6 -GPLD1 ENSG00000112293 Glycosylphosphatidylinositol specific phospholipase D1 6 24424565-24495205 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB008625, HPA012500 Uncertain Tissue enhanced 0 liver: 23.7 skin: 9.0 -ALDH5A1 SSADH, SSDH ENSG00000112294 Aldehyde dehydrogenase 5 family, member A1 6 24494852-24537207 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029715, HPA029716 Supported Validated Mitochondria Expressed in all liver: 46.8 -AIM1 CRYBG1, ST4 ENSG00000112297 Absent in melanoma 1 6 106360808-106571978 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026378, HPA030948, HPA030949 Approved Approved Nucleus
Microtubules
Cytosol Tissue enhanced 0 placenta: 106.9 esophagus: 71.6 -VNN1 Tiff66 ENSG00000112299 Vanin 1 6 132681590-132714049 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064145 Approved Group enriched 5 duodenum: 176.1;gallbladder: 175.5;liver: 142.6;small intestine: 108.8 kidney: 27.4 -VNN2 FOAP-4, GPI-80 ENSG00000112303 Vanin 2 6 132743870-132763459 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 spleen: 77.9 lymph node: 45.5 -ACOT13 HT012, THEM2 ENSG00000112304 Acyl-CoA thioesterase 13 6 24667035-24705065 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019881 Approved Approved Cell Junctions Expressed in all kidney: 20.9 -SMAP1 FLJ13159, SMAP-1 ENSG00000112305 Small ArfGAP 1 6 70667776-70862015 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030574 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Expressed in all testis: 51.1 -RPS12 S12 ENSG00000112306 Ribosomal protein S12 6 132814441-132817564 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006124, HPA006365 Approved Supported Cytosol Expressed in all ovary: 3951.0 -C6orf62 DKFZP564G182, FLJ12619, XTP12 ENSG00000112308 Chromosome 6 open reading frame 62 6 24704861-24720836 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA030564, HPA030566 Supported Approved Cytosol Expressed in all testis: 173.7 -B3GAT2 GlcAT-S ENSG00000112309 Beta-1,3-glucuronyltransferase 2 6 70856679-70957038 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA012059 Uncertain Tissue enriched 10 cerebral cortex: 19.6 testis: 1.9 -GMNN Gem ENSG00000112312 Geminin, DNA replication inhibitor 6 24774931-24786099 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011458, CAB047327, CAB047328, HPA049977, HPA054597 Supported Validated Nucleoplasm Expressed in all prostate: 70.5 -EYA4 CMD1J, DFNA10 ENSG00000112319 EYA transcriptional coactivator and phosphatase 4 6 133240598-133532120 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004805, HPA038771, HPA038772 Approved Approved Nucleoplasm Tissue enhanced 0 seminal vesicle: 16.3 fallopian tube: 11.7 -SOBP FLJ10159 ENSG00000112320 Sine oculis binding protein homolog 6 107489958-107660167 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA029242 Uncertain Approved Nucleoplasm
Vesicles Tissue enhanced 0 cerebral cortex: 26.5 ovary: 13.7 -NR2E1 TLL, TLX, XTLL ENSG00000112333 Nuclear receptor subfamily 2, group E, member 1 6 108166058-108188809 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA036954, HPA055642 Approved Approved Nuclear bodies Tissue enriched 46 cerebral cortex: 11.5 parathyroid gland: 0.2 -SNX3 Grd19 ENSG00000112335 Sorting nexin 3 6 108211222-108261260 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all adrenal gland: 290.0 -SLC17A2 NPT3 ENSG00000112337 Solute carrier family 17, member 2 6 25912754-25930726 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038270 Uncertain Tissue enriched 85 liver: 40.9 testis: 0.4 -HBS1L DKFZp434g247, EF-1a, eRF3c, ERFS, HBS1, HSPC276, KIAA1038 ENSG00000112339 HBS1-like translational GTPase 6 134960378-135103056 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029728, HPA029729 Approved Approved Nuclear bodies
Cytosol Expressed in all cerebral cortex: 73.4 -TRIM38 RNF15, RORET ENSG00000112343 Tripartite motif containing 38 6 25962802-25991226 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031685 Approved Approved Plasma membrane
Cell Junctions
Centrosome Mixed spleen: 20.1 -PEX7 PTS2R, RD ENSG00000112357 Peroxisomal biogenesis factor 7 6 136822564-136913937 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049202 Uncertain Expressed in all parathyroid gland: 24.8 -ZBTB24 BIF1, KIAA0441, PATZ2, ZNF450 ENSG00000112365 Zinc finger and BTB domain containing 24 6 109462594-109483237 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017872, HPA049003 Uncertain Approved Nucleus
Cytokinetic bridge
Centrosome Mixed parathyroid gland: 13.7 -FIG4 ALS11, CMT4J, dJ249I4.1, hSac3, KIAA0274, SAC3 ENSG00000112367 FIG4 phosphoinositide 5-phosphatase 6 109691312-109825428 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017823, HPA068859 Approved Approved Vesicles
Lipid droplets Expressed in all parathyroid gland: 32.6 -PERP dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW ENSG00000112378 PERP, TP53 apoptosis effector 6 138088505-138107511 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA022269 Supported Group enriched 6 esophagus: 574.1;skin: 1238.6 breast: 149.6 -ARFGEF3 BIG3, C6orf92, dJ171N11.1, KIAA1244, PPP1R33 ENSG00000112379 ARFGEF family member 3 6 138161921-138344663 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036350 Uncertain Tissue enhanced 0 cerebral cortex: 23.7;parathyroid gland: 29.2 prostate: 19.3 -SLC16A10 MCT10, TAT1 ENSG00000112394 Solute carrier family 16 (aromatic amino acid transporter), member 10 6 111087503-111231194 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016860 Approved Approved Vesicles
Cell Junctions Tissue enhanced 0 placenta: 38.2 skin: 22.5 -HECA dJ225E12.1, HDC, HDCL, hHDC ENSG00000112406 Hdc homolog, cell cycle regulator 6 139135112-139180802 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042313 Uncertain Expressed in all spleen: 38.7 -ADGRG6 FLJ14937, GPR126 ENSG00000112414 Adhesion G protein-coupled receptor G6 6 142301854-142446266 G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017346 Approved Tissue enhanced 0 placenta: 66.6 liver: 36.9 -PHACTR2 C6orf56, KIAA0680 ENSG00000112419 Phosphatase and actin regulator 2 6 143536845-143831185 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031719, HPA031720, HPA031725 Approved Expressed in all placenta: 119.1 -EPM2A LD, LDE ENSG00000112425 Epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 6 145501583-145736024 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053643, HPA055468 Validated Nucleoplasm Mixed skeletal muscle: 22.1 -OR12D3 hs6M1-27 ENSG00000112462 Olfactory receptor, family 12, subfamily D, member 3 6 29373423-29375291 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -SLC39A7 D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7 ENSG00000112473 Solute carrier family 39 (zinc transporter), member 7 6 33200445-33204439 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053999 Approved Supported Endoplasmic reticulum Expressed in all parathyroid gland: 40.2 -CCR6 BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22 ENSG00000112486 Chemokine (C-C motif) receptor 6 6 167111807-167139696 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB006820, HPA014488 Approved Tissue enhanced 0 lymph node: 20.6;tonsil: 33.8 spleen: 17.3 -UNC93A dJ366N23.1, dJ366N23.2 ENSG00000112494 Unc-93 homolog A (C. elegans) 6 167271169-167316019 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA035729 Uncertain Tissue enhanced 0 duodenum: 9.9;skin: 17.9 liver: 7.1 -SLC22A2 OCT2 ENSG00000112499 Solute carrier family 22 (organic cation transporter), member 2 6 160171061-160277638 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008567, CAB068236, CAB068237 Supported Tissue enriched 83 kidney: 149.2 seminal vesicle: 1.7 -PHF1 MTF2L2, TDRD19C ENSG00000112511 PHD finger protein 1 6 33410399-33416453 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031038 Approved Approved Nucleoplasm Mixed testis: 16.2 -CUTA ACHAP, C6orf82 ENSG00000112514 CutA divalent cation tolerance homolog (E. coli) 6 33416442-33418317 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016787, HPA064369 Uncertain Approved Plasma membrane
Focal adhesion sites Expressed in all thyroid gland: 292.6 -PACRG FLJ32724, Glup, HAK005771, PARK2CRG ENSG00000112530 PARK2 co-regulated 6 162727132-163315492 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066293 Supported Tissue enhanced 0 fallopian tube: 56.4;testis: 53.1 epididymis: 12.1 -QKI QK3 ENSG00000112531 QKI, KH domain containing, RNA binding 6 163414000-163578596 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019123, CAB022602 Supported Supported Supported Nucleoplasm Expressed in all cerebral cortex: 360.6 -C6orf118 bA85G2.1, MGC23884 ENSG00000112539 Chromosome 6 open reading frame 118 6 165279664-165309607 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029787, HPA029789 Approved Uncertain Mitochondria Group enriched 6 fallopian tube: 25.9;testis: 12.8 lung: 3.2 -PDE10A ENSG00000112541 Phosphodiesterase 10A 6 165327287-165986603 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045998, HPA047200 Supported Tissue enhanced 0 thyroid gland: 14.4 testis: 12.2 -MDFI I-mfa ENSG00000112559 MyoD family inhibitor 6 41636882-41654246 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049973 Approved Supported Nucleoplasm Tissue enhanced 0 adipose tissue: 35.9 gallbladder: 19.8 -TFEB bHLHe35, TCFEB ENSG00000112561 Transcription factor EB 6 41683978-41736259 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049532 Supported Nucleoplasm Expressed in all parathyroid gland: 53.4 -SMOC2 SMAP2 ENSG00000112562 SPARC related modular calcium binding 2 6 168441151-168673445 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB033979 Uncertain Mixed endometrium: 182.8 -CCND3 ENSG00000112576 Cyclin D3 6 41934933-42050357 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000116, HPA055107 Approved Supported Plasma membrane
Focal adhesion sites
Cytosol Expressed in all lymph node: 161.4 -BYSL ENSG00000112578 Bystin-like 6 41921188-41933046 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031217, HPA031219 Supported Validated Nucleus
Nucleoli Expressed in all smooth muscle: 11.5 -FAM120B CCPG, KIAA1838, PGCC1 ENSG00000112584 Family with sequence similarity 120B 6 170290703-170407065 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037518, HPA037519 Uncertain Approved Nucleoplasm
Cytosol Expressed in all fallopian tube: 16.3 -TBP GTF2D1, SCA17, TFIID ENSG00000112592 TATA box binding protein 6 170554302-170572870 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009442, HPA049805 Approved Supported Nucleoplasm Expressed in all testis: 65.3 -GUCA1B GCAP2, RP48 ENSG00000112599 Guanylate cyclase activator 1B (retina) 6 42184401-42194916 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031453 Uncertain Mixed skin: 4.2 -PRPH2 CACD2, rd2, RDS, RP7, TSPAN22 ENSG00000112619 Peripherin 2 (retinal degeneration, slow) 6 42696600-42722574 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029458 Supported Mixed parathyroid gland: 8.5 -GLTSCR1L KIAA0240 ENSG00000112624 GLTSCR1-like 6 42746958-42868560 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029390, HPA029391 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 21.5 -PPP2R5D B56D ENSG00000112640 Protein phosphatase 2, regulatory subunit B', delta 6 42984499-43012342 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029045, HPA029046 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 43.2 -MRPL2 CGI-22, MRP-L14, RPML14 ENSG00000112651 Mitochondrial ribosomal protein L2 6 43054029-43059806 Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007455, HPA064814 Approved Approved Nucleoplasm
Mitochondria Expressed in all parathyroid gland: 33.1 -PTK7 CCK4 ENSG00000112655 Protein tyrosine kinase 7 (inactive) 6 43076268-43161719 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003222 Approved Mixed endometrium: 117.0 -SRF MCM1 ENSG00000112658 Serum response factor 6 43171299-43181507 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001819, CAB005416 Supported Supported Nucleus Expressed in all smooth muscle: 69.3 -CUL9 H7AP1, KIAA0708, PARC ENSG00000112659 Cullin 9 6 43182175-43224587 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016434, HPA052004 Approved Approved Cytosol Mixed testis: 10.0 -DNPH1 C6orf108, dJ330M21.3, rcl ENSG00000112667 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 6 43225629-43229484 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029675, HPA029676 Supported Approved Nucleoplasm
Cytosol Expressed in all duodenum: 107.2 -DUSP22 JKAP, JSP1, MKPX, VHX ENSG00000112679 Dual specificity phosphatase 22 6 291630-351355 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031394 Approved Approved Nucleoplasm
Vesicles Expressed in all testis: 85.1 -EXOC2 FLJ11026, SEC5L1, Sec5p ENSG00000112685 Exocyst complex component 2 6 485133-693111 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032093 Uncertain Supported Vesicles Expressed in all testis: 30.6 -COX7A2 COX7AL, COXVIIa-L ENSG00000112695 Cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 6 75237675-75250323 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all testis: 635.8 -TMEM30A C6orf67, CDC50A, FLJ10856 ENSG00000112697 Transmembrane protein 30A 6 75252924-75284968 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014561 Approved Supported Mitochondria Expressed in all cerebral cortex: 167.9 -GMDS GMD, SDR3E1 ENSG00000112699 GDP-mannose 4,6-dehydratase 6 1623806-2245692 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031528 Approved Mixed duodenum: 109.2 -SENP6 KIAA0797, SUSP1 ENSG00000112701 SUMO1/sentrin specific peptidase 6 6 75601509-75718278 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024376 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 73.9 -IMPG1 GP147, IPM150, SPACR ENSG00000112706 Interphotoreceptor matrix proteoglycan 1 6 75921115-76072678 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027142, HPA030332, HPA030333 Supported Mixed epididymis: 2.6 -VEGFA VEGF, VEGF-A, VPF ENSG00000112715 Vascular endothelial growth factor A 6 43770184-43786487 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005429, CAB039240, HPA069116 Approved Expressed in all thyroid gland: 455.6 -PRPF4B KIAA0536, PR4H, Prp4 ENSG00000112739 Pre-mRNA processing factor 4B 6 4021267-4064983 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020638 Approved Supported Nuclear speckles Expressed in all thyroid gland: 37.5 -TTK CT96, MPH1, MPS1, MPS1L1 ENSG00000112742 TTK protein kinase 6 80003887-80042527 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010166, CAB013229 Approved Approved Nucleoli
Cytosol Tissue enhanced 0 testis: 60.5 bone marrow: 15.5 -SLC29A1 ENT1 ENSG00000112759 Solute carrier family 29 (equilibrative nucleoside transporter), member 1 6 44219505-44234151 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012384 Approved Expressed in all adrenal gland: 125.1 -WISP3 CCN6 ENSG00000112761 WNT1 inducible signaling pathway protein 3 6 112054072-112070969 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062438, HPA064196 Approved Endoplasmic reticulum Tissue enhanced 0 epididymis: 3.0 skin: 2.0 -BTN2A1 BT2.1, BTF1, BTN2.1 ENSG00000112763 Butyrophilin, subfamily 2, member A1 6 26457904-26476621 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019208 Approved Approved Plasma membrane Expressed in all placenta: 26.1 -LAMA4 LAMA3 ENSG00000112769 Laminin, alpha 4 6 112108760-112254939 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015693, CAB078156 Approved Approved Plasma membrane
Cytosol Mixed smooth muscle: 144.6 -FAM46A C6orf37, FLJ20037 ENSG00000112773 Family with sequence similarity 46, member A 6 81491439-81752774 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051067, HPA067140 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 bone marrow: 143.9 gallbladder: 51.6 -CLIC5 DFNB102 ENSG00000112782 Chloride intracellular channel 5 6 45898451-46080395 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA074371 Supported Nuclear speckles
Plasma membrane Tissue enhanced 0 lung: 116.4;skeletal muscle: 119.2 heart muscle: 72.3 -FBRSL1 KIAA1545 ENSG00000112787 Fibrosin-like 1 12 132489551-132585188 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049880 Approved Approved Nucleus
Plasma membrane
Cytosol Expressed in all spleen: 11.5 -ENPP5 ENSG00000112796 Ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 6 46159187-46170971 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA016902 Approved Tissue enhanced 0 epididymis: 291.6 thyroid gland: 85.2 -LY86 dJ80N2.1, MD-1 ENSG00000112799 Lymphocyte antigen 86 6 6588108-6654983 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025000, HPA044895 Approved Tissue enhanced 0 lymph node: 83.7 spleen: 67.5 -PRSS16 TSSP ENSG00000112812 Protease, serine, 16 (thymus) 6 27247701-27256624 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA017743 Uncertain Tissue enhanced 0 thyroid gland: 21.8 epididymis: 16.0 -MEP1A PPHA ENSG00000112818 Meprin A, alpha (PABA peptide hydrolase) 6 46793390-46839782 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025163, HPA029416 Supported Group enriched 41 colon: 120.0;duodenum: 290.0;rectum: 116.2;small intestine: 549.0 appendix: 6.5 -TBX18 ENSG00000112837 T-box 18 6 84687351-84764519 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed adipose tissue: 6.1 -ERBB2IP ERBIN, LAP2 ENSG00000112851 Erbb2 interacting protein 5 65926475-66082549 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048606, HPA059863 Approved Supported Nuclear speckles
Plasma membrane Expressed in all testis: 49.9 -PCDHB2 PCDH-BETA2 ENSG00000112852 Protocadherin beta 2 5 141094578-141098703 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA007548 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 10.0 cerebral cortex: 7.7 -HARS2 HARSL, HARSR, HO3 ENSG00000112855 Histidyl-tRNA synthetase 2, mitochondrial 5 140691426-140699291 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035941 Approved Approved Cytosol Expressed in all parathyroid gland: 35.8 -NUDT12 DKFZP761I172 ENSG00000112874 Nudix (nucleoside diphosphate linked moiety X)-type motif 12 5 103548855-103562793 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045449 Supported Mixed parathyroid gland: 44.3 -CEP72 FLJ10565, KIAA1519 ENSG00000112877 Centrosomal protein 72kDa 5 612272-667168 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058235, HPA074879 Approved Supported Centrosome Tissue enhanced 0 testis: 10.5 ovary: 3.3 -MAN2A1 GOLIM7, MANA2 ENSG00000112893 Mannosidase, alpha, class 2A, member 1 5 109689366-109869625 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022377, HPA026896 Supported Supported Golgi apparatus Expressed in all parathyroid gland: 39.9 -SEMA5A SEMAF, semF ENSG00000112902 Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 5 9035026-9546075 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004632 Approved Mixed cervix: 19.2 -C7 ENSG00000112936 Complement component 7 5 40909252-40982939 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001465 Approved Tissue enhanced 0 adrenal gland: 1120.3 placenta: 710.8 -PAPD7 LAK-1, POLK, POLS, TRF4, TRF4-1 ENSG00000112941 PAP associated domain containing 7 5 6713007-6757048 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045487, HPA046742 Supported Supported Nucleoplasm
Nuclear membrane
Golgi apparatus Expressed in all testis: 19.0 -GHR GHBP ENSG00000112964 Growth hormone receptor 5 42423777-42721878 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045339, HPA057705 Supported Supported Plasma membrane
Cytosol
Cytoplasmic bodies Group enriched 5 adipose tissue: 91.1;liver: 110.5 prostate: 18.4 -HMGCS1 HMGCS ENSG00000112972 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 5 43289395-43313512 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032907, HPA036913, HPA036914 Approved Supported Nucleus
Plasma membrane
Cytosol Expressed in all liver: 208.6 -DAP ENSG00000112977 Death-associated protein 5 10679230-10761272 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029456 Uncertain Approved Nucleoplasm
Vesicles
Mitochondria Expressed in all parathyroid gland: 153.7 -NME5 nm23-H5, RSPH23 ENSG00000112981 NME/NM23 family member 5 5 138115172-138139443 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035648, HPA044555 Approved Approved Nucleoplasm
Nuclear bodies Tissue enhanced 0 fallopian tube: 58.7;testis: 94.3 epididymis: 27.7 -BRD8 p120, SMAP ENSG00000112983 Bromodomain containing 8 5 138139766-138178986 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001841 Supported Approved Nucleoplasm
Mitochondria Expressed in all testis: 147.8 -KIF20A RAB6KIFL ENSG00000112984 Kinesin family member 20A 5 138178719-138187715 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036909, HPA036910 Approved Supported Nucleoplasm Tissue enhanced 0 testis: 20.1 tonsil: 12.0 -NNT ENSG00000112992 Nicotinamide nucleotide transhydrogenase 5 43602692-43707405 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004829, CAB004975 Supported Validated Mitochondria Expressed in all heart muscle: 139.6 -MRPS30 PAP, PDCD9 ENSG00000112996 Mitochondrial ribosomal protein S30 5 44808925-44820428 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018686, HPA021149 Supported Expressed in all breast: 23.5 -HSPA9 GRP75, HSPA9B, mot-2, mthsp75, PBP74 ENSG00000113013 Heat shock 70kDa protein 9 (mortalin) 5 138554882-138575444 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000898, CAB005219 Supported Validated Mitochondria Expressed in all parathyroid gland: 259.4 -MRPS27 KIAA0264 ENSG00000113048 Mitochondrial ribosomal protein S27 5 72219409-72320646 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071751 Approved Expressed in all thyroid gland: 59.3 -PFDN1 PFD1 ENSG00000113068 Prefoldin subunit 1 5 140245039-140303121 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006499 Approved Approved Nucleoli
Plasma membrane
Cytosol Expressed in all cerebral cortex: 106.6 -HBEGF DTR, DTS, HEGFL ENSG00000113070 Heparin-binding EGF-like growth factor 5 140332843-140346631 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053243 Uncertain Expressed in all gallbladder: 89.2 -SLC4A9 AE4 ENSG00000113073 Solute carrier family 4, sodium bicarbonate cotransporter, member 9 5 140360202-140375143 Plasma proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051307 Uncertain Tissue enriched 17 kidney: 12.1 testis: 0.6 -LOX ENSG00000113083 Lysyl oxidase 5 122063195-122078285 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043930 Supported Endoplasmic reticulum Mixed adipose tissue: 28.4 -GZMK PRSS, TRYP2 ENSG00000113088 Granzyme K (granzyme 3; tryptase II) 5 55024253-55034570 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063181 Supported Tissue enhanced 0 lymph node: 105.6 spleen: 42.5 -CDH9 ENSG00000113100 Cadherin 9, type 2 (T1-cadherin) 5 26880600-27121150 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA007167 Uncertain Tissue enhanced 0 breast: 16.7;cerebral cortex: 11.4 testis: 6.6 -APBB3 FE65L2 ENSG00000113108 Amyloid beta (A4) precursor protein-binding, family B, member 3 5 140558268-140593752 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005571 Uncertain Supported Actin filaments
Cytosol Tissue enhanced 0 cerebral cortex: 11.7 testis: 6.8 -TMCO6 FLJ39769, PRO1580 ENSG00000113119 Transmembrane and coiled-coil domains 6 5 140639427-140645408 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037473, HPA037474 Uncertain Approved Nucleoplasm
Mitochondria Mixed testis: 13.6 -SPARC ON ENSG00000113140 Secreted protein, acidic, cysteine-rich (osteonectin) 5 151661096-151687165 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002306, HPA002989, HPA003020 Supported Expressed in all placenta: 3224.6 -IK ENSG00000113141 IK cytokine, down-regulator of HLA II 5 140647058-140662479 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048798 Supported Validated Nuclear speckles Expressed in all fallopian tube: 228.5 -HMGCR ENSG00000113161 3-hydroxy-3-methylglutaryl-CoA reductase 5 75336329-75362104 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008338, CAB016797 Approved Expressed in all cerebral cortex: 87.8 -COL4A3BP CERT, GPBP, STARD11 ENSG00000113163 Collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 5 75368486-75512138 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035645, HPA042608 Uncertain Validated Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 70.3 -FAF2 ETEA, KIAA0887, UBXD8, UBXN3B ENSG00000113194 Fas associated factor family member 2 5 176447628-176510074 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065968, HPA073828 Validated Endoplasmic reticulum
Lipid droplets Expressed in all parathyroid gland: 41.2 -HAND1 bHLHa27, eHand, Hxt, Thing1 ENSG00000113196 Heart and neural crest derivatives expressed 1 5 154474972-154478264 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040925 Approved Uncertain Nucleus
Nuclear membrane Tissue enhanced 0 smooth muscle: 16.6 adrenal gland: 6.3 -PCDHB3 PCDH-BETA3 ENSG00000113205 Protocadherin beta 3 5 141100473-141103827 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA050296 Uncertain Supported Vesicles Tissue enhanced 0 testis: 10.4 endometrium: 2.3 -PCDHB5 DKFZp586B0217, PCDH-BETA5 ENSG00000113209 Protocadherin beta 5 5 141135218-141138625 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA013191 Approved Mixed ovary: 7.3 -PCDHB6 PCDH-BETA6 ENSG00000113211 Protocadherin beta 6 5 141150022-141153287 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029566 Uncertain Uncertain Nucleus
Plasma membrane
Cytosol Tissue enhanced 0 parathyroid gland: 7.1 testis: 3.5 -PCDHB7 PCDH-BETA7 ENSG00000113212 Protocadherin beta 7 5 141172619-141176383 Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059271 Approved Tissue enhanced 0 endometrium: 6.6 smooth muscle: 4.4 -PDE8B ENSG00000113231 Phosphodiesterase 8B 5 77210449-77429807 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036911, HPA036912 Supported Approved Nucleoplasm
Cytosol Tissue enriched 5 thyroid gland: 292.2 cerebral cortex: 53.2 -CLK4 ENSG00000113240 CDC-like kinase 4 5 178602664-178630615 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043746 Approved Approved Actin filaments Expressed in all testis: 22.4 -PCDHB15 PCDH-BETA15 ENSG00000113248 Protocadherin beta 15 5 141245349-141249365 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA007172, CAB026471 Uncertain Mixed cerebral cortex: 12.7 -HAVCR1 CD365, HAVCR, HAVCR-1, TIM-1, TIM1, TIMD1 ENSG00000113249 Hepatitis A virus cellular receptor 1 5 157029413-157059119 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA007173 Approved Vesicles Group enriched 5 colon: 4.9;kidney: 8.2;rectum: 4.2;testis: 1.7 parathyroid gland: 0.9 -GRM6 CSNB1B, GPRC1F, mGlu6, MGLUR6 ENSG00000113262 Glutamate receptor, metabotropic 6 5 178978327-178996206 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014511 Supported Not detected testis: 0.8 -ITK EMT, LYK, PSCTK2 ENSG00000113263 IL2-inducible T-cell kinase 5 157142933-157255191 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 20.9;lymph node: 33.6;tonsil: 23.0 spleen: 14.0 -RNF130 G1RZFP, GOLIATH, GP ENSG00000113269 Ring finger protein 130 5 179911651-180072118 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014499 Approved Expressed in all adipose tissue: 74.3 -THG1L FLJ11601, FLJ20546, hTHG1, ICF45, IHG-1 ENSG00000113272 TRNA-histidine guanylyltransferase 1-like 5 157731197-157741448 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035877, HPA035878 Approved Mixed thyroid gland: 10.3 -ARSB ENSG00000113273 Arylsulfatase B 5 78777209-78986087 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037770, HPA037771 Supported Mixed smooth muscle: 18.4 -CLINT1 CLINT, ENTH, EPNR, KIAA0171 ENSG00000113282 Clathrin interactor 1 5 157785743-157859175 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043280, HPA056947 Supported Supported Nucleoplasm
Vesicles Expressed in all parathyroid gland: 167.9 -THBS4 ENSG00000113296 Thrombospondin 4 5 79991311-80083287 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004597, HPA042426 Approved Approved Vesicles Group enriched 5 adipose tissue: 234.3;heart muscle: 92.7;smooth muscle: 384.5 thyroid gland: 44.6 -CNOT6 CCR4, Ccr4a, KIAA1194 ENSG00000113300 CCR4-NOT transcription complex, subunit 6 5 180494412-180578405 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044568 Approved Approved Cytosol Expressed in all testis: 25.0 -IL12B CLMF, CLMF2, IL-12B, NKSF, NKSF2 ENSG00000113302 Interleukin 12B 5 159314783-159330887 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040970 Approved Not detected spleen: 0.6 -BTNL8 BTN9.2, FLJ21458 ENSG00000113303 Butyrophilin-like 8 5 180899077-180950906 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039738 Approved Group enriched 6 colon: 26.5;duodenum: 120.7;rectum: 28.2;small intestine: 96.1 gallbladder: 10.5 -TTC1 TPR1 ENSG00000113312 Tetratricopeptide repeat domain 1 5 160009113-160065543 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036557, HPA057502 Approved Validated Cytosol Expressed in all cerebral cortex: 80.6 -MSH3 DUP, MRP1 ENSG00000113318 MutS homolog 3 5 80654648-80876460 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036081 Approved Nuclear bodies Expressed in all thyroid gland: 18.6 -RASGRF2 GRF2, Ras-GRF2 ENSG00000113319 Ras protein-specific guanine nucleotide-releasing factor 2 5 80960672-81230156 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018679 Uncertain Supported Endoplasmic reticulum Tissue enhanced 0 cerebral cortex: 22.4 ovary: 15.1 -GABRG2 ENSG00000113327 Gamma-aminobutyric acid (GABA) A receptor, gamma 2 5 162067540-162155536 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 9 cerebral cortex: 74.3 adrenal gland: 8.2 -CCNG1 CCNG ENSG00000113328 Cyclin G1 5 163437569-163446151 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB000350 Supported Supported Nucleoplasm Expressed in all duodenum: 141.4 -POLR3G RPC32, RPC7 ENSG00000113356 Polymerase (RNA) III (DNA directed) polypeptide G (32kD) 5 90471748-90514553 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010109, HPA052658 Supported Supported Nucleoplasm Mixed parathyroid gland: 17.0 -DROSHA Etohi2, HSA242976, RN3, RNASE3L, RNASEN ENSG00000113360 Drosha, ribonuclease type III 5 31400497-31532196 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031150 Approved Nucleoplasm
Plasma membrane Expressed in all parathyroid gland: 30.0 -CDH6 ENSG00000113361 Cadherin 6, type 2, K-cadherin (fetal kidney) 5 31193750-31329146 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007047, HPA007456, CAB025274 Approved Mixed kidney: 15.9 -LMNB1 ENSG00000113368 Lamin B1 5 126776623-126837020 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005269, HPA050524, HPA053579 Supported Validated Nuclear membrane Tissue enhanced 0 lymph node: 41.9 appendix: 37.3 -ARRDC3 KIAA1376 ENSG00000113369 Arrestin domain containing 3 5 91368724-91383359 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 142.5 -GOLPH3 GOPP1, GPP34, MIDAS, Vps74 ENSG00000113384 Golgi phosphoprotein 3 (coat-protein) 5 32124704-32174350 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044564, HPA055841 Approved Supported Golgi apparatus
Vesicles Expressed in all gallbladder: 120.9 -SUB1 p14, p15, PC4 ENSG00000113387 SUB1 homolog, transcriptional regulator 5 32531633-32604079 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001311, CAB015351 Supported Supported Nucleus
Nucleoli Expressed in all cerebral cortex: 235.1 -NPR3 ANPRC, C5orf23, FLJ14054, GUCY2B, NPRC ENSG00000113389 Natriuretic peptide receptor 3 5 32689070-32791724 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031065, HPA052702 Uncertain Approved Cytosol Tissue enriched 5 kidney: 113.3 adipose tissue: 21.9 -FAM172A C5orf21, DKFZP564D172 ENSG00000113391 Family with sequence similarity 172, member A 5 93618069-94111699 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA012299, HPA045505 Approved Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 26.9 -SLC27A6 ACSVL2, FACVL2, FATP6, VLCS-H1 ENSG00000113396 Solute carrier family 27 (fatty acid transporter), member 6 5 128538013-129033642 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA008987 Approved Approved Nuclear bodies Tissue enhanced 0 adrenal gland: 32.7;fallopian tube: 33.7 testis: 24.1 -TARS ENSG00000113407 Threonyl-tRNA synthetase 5 33440696-33469539 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037425 Approved Supported Actin filaments
Cytosol Expressed in all thyroid gland: 44.3 -IRX4 ENSG00000113430 Iroquois homeobox 4 5 1877413-1887236 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064094 Uncertain Nucleus
Vesicles Tissue enhanced 0 prostate: 5.0;skin: 6.9 esophagus: 1.4 -LNPEP CAP, P-LAP, PLAP ENSG00000113441 Leucyl/cystinyl aminopeptidase 5 96935394-97037515 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043642 Approved Mixed parathyroid gland: 22.9 -PDE4D DPDE3 ENSG00000113448 Phosphodiesterase 4D, cAMP-specific 5 58969038-60522120 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045895 Approved Approved Nuclear membrane
Plasma membrane
Cytosol Mixed bone marrow: 46.6 -RAD1 HRAD1, REC1 ENSG00000113456 RAD1 checkpoint DNA exonuclease 5 34905264-34918989 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006692 Approved Supported Nucleoplasm
Vesicles Mixed testis: 11.9 -BRIX1 BRIX, BXDC2, FLJ11100 ENSG00000113460 BRX1, biogenesis of ribosomes 5 34915376-34925996 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039614 Approved Validated Nucleoli Expressed in all placenta: 27.4 -AGXT2 AGT2 ENSG00000113492 Alanine--glyoxylate aminotransferase 2 5 34998101-35048135 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037382 Approved Group enriched 32 kidney: 196.2;liver: 59.1 small intestine: 4.0 -PRLR ENSG00000113494 Prolactin receptor 5 35048756-35230589 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 placenta: 70.3 kidney: 32.9 -SLC12A7 DKFZP434F076, KCC4 ENSG00000113504 Solute carrier family 12 (potassium/chloride transporter), member 7 5 1050376-1112035 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041652 Approved Uncertain Cytosol Mixed duodenum: 25.0 -IL4 BCGF-1, BCGF1, BSF1, IL-4, MGC79402 ENSG00000113520 Interleukin 4 5 132673986-132682676 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 parathyroid gland: 2.2 fallopian tube: 1.0 -RAD50 hRad50, RAD50-2 ENSG00000113522 RAD50 homolog, double strand break repair protein 5 132556019-132646344 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022103, CAB024979, HPA052291 Supported Validated Nucleoplasm Expressed in all epididymis: 21.2 -IL5 EDF, IL-5, TRF ENSG00000113525 Interleukin 5 5 132541444-132556838 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB010304 Approved Tissue enriched 9 testis: 9.7 epididymis: 1.1 -ST8SIA4 PST, PST1, SIAT8D ENSG00000113532 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 5 100806935-100903266 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051126, HPA053995 Approved Approved Golgi apparatus Mixed appendix: 19.8 -GNPDA1 GNPDA, GNPI, GPI, HLN, KIAA0060 ENSG00000113552 Glucosamine-6-phosphate deaminase 1 5 141991749-142013041 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000499, HPA046891 Uncertain Approved Golgi apparatus
Vesicles Expressed in all kidney: 77.1 -PCDH12 VE-cadherin-2 ENSG00000113555 Protocadherin 12 5 141943585-141969741 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051242 Uncertain Tissue enhanced 0 placenta: 38.5 spleen: 22.9 -SKP1 EMC19, MGC34403, OCP-II, OCP2, p19A, SKP1A, TCEB1L ENSG00000113558 S-phase kinase-associated protein 1 5 134148935-134177038 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012982, HPA053745, HPA058134 Approved Supported Nucleus
Cytosol Expressed in all cerebral cortex: 932.4 -NUP155 KIAA0791, N155 ENSG00000113569 Nucleoporin 155kDa 5 37288137-37371181 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037775 Uncertain Validated Nuclear membrane Tissue enriched 9 testis: 126.2 parathyroid gland: 14.1 -PPP2CA PP2Calpha ENSG00000113575 Protein phosphatase 2, catalytic subunit, alpha isozyme 5 134194334-134226142 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003848, HPA043236 Approved Expressed in all cerebral cortex: 127.0 -FGF1 AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1 ENSG00000113578 Fibroblast growth factor 1 (acidic) 5 142592178-142698070 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003265, CAB017519 Supported Validated Nucleoplasm Tissue enhanced 0 cerebral cortex: 130.3;kidney: 59.1 heart muscle: 32.8 -NR3C1 GR, GRL ENSG00000113580 Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 5 143277931-143435512 Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004248, CAB010435 Supported Validated Nucleoplasm
Mitochondria
Cytosol Expressed in all placenta: 66.4 -C5orf15 HTGN29, KCT2 ENSG00000113583 Chromosome 5 open reading frame 15 5 133955502-133968787 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA011951, HPA039165 Uncertain Approved Golgi apparatus Expressed in all thyroid gland: 81.4 -PPWD1 KIAA0073 ENSG00000113593 Peptidylprolyl isomerase domain and WD repeat containing 1 5 65563236-65587549 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019353, HPA019360 Approved Supported Nuclear bodies Expressed in all lymph node: 32.0 -LIFR CD118 ENSG00000113594 Leukemia inhibitory factor receptor alpha 5 38474963-38608354 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004478, CAB010252 Approved Approved Nuclear speckles
Golgi apparatus Mixed thyroid gland: 71.7 -TRIM23 ARD1, ARFD1, RNF46 ENSG00000113595 Tripartite motif containing 23 5 65589680-65625975 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039605 Approved Expressed in all cerebral cortex: 47.0 -TRAPPC13 C5orf44, FLJ13611, FLJ26957, MGC48585 ENSG00000113597 Trafficking protein particle complex 13 5 65624716-65666233 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037777 Approved Approved Nucleus
Plasma membrane Expressed in all prostate: 30.0 -C9 ENSG00000113600 Complement component 9 5 39284262-39424868 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002151, HPA029577 Uncertain Uncertain Plasma membrane
Cytosol Tissue enriched 119 liver: 728.8 epididymis: 6.1 -SEC24A ENSG00000113615 SEC24 homolog A, COPII coat complex component 5 134648789-134727823 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038901, HPA056825 Approved Approved Nucleoli fibrillar center
Vesicles Expressed in all parathyroid gland: 25.3 -TXNDC15 2310047H23Rik, C5orf14, FLJ22625 ENSG00000113621 Thioredoxin domain containing 15 5 134873803-134901525 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015483 Approved Approved Golgi apparatus Expressed in all thyroid gland: 83.7 -TTC33 OSRF ENSG00000113638 Tetratricopeptide repeat domain 33 5 40714475-40755975 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038252, HPA038253 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Mixed cerebral cortex: 25.5 -RARS DALRD1 ENSG00000113643 Arginyl-tRNA synthetase 5 168486445-168519299 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003979, HPA004130 Approved Validated Nucleoplasm
Cytosol Expressed in all duodenum: 55.9 -WWC1 KIAA0869, KIBRA, PPP1R168 ENSG00000113645 WW and C2 domain containing 1 5 168291651-168472303 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038016, HPA038017 Approved Approved Golgi apparatus Mixed salivary gland: 61.9 -H2AFY macroH2A1.2 ENSG00000113648 H2A histone family, member Y 5 135333900-135399914 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041189, HPA050962 Supported Supported Nucleus Expressed in all bone marrow: 155.9 -TCERG1 CA150, TAF2S, Urn1 ENSG00000113649 Transcription elongation regulator 1 5 146447311-146511961 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064854, HPA069752, HPA069808 Supported Validated Nucleoplasm Expressed in all lymph node: 21.0 -DPYSL3 CRMP4, DRP-3, ULIP ENSG00000113657 Dihydropyrimidinase-like 3 5 147390811-147510056 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010948 Approved Supported Cytosol Tissue enhanced 0 smooth muscle: 306.1 seminal vesicle: 221.1 -SMAD5 Dwfc, JV5-1, MADH5 ENSG00000113658 SMAD family member 5 5 136132845-136188747 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058931 Approved Supported Nucleoplasm
Cytosol Expressed in all endometrium: 42.9 -CSNK1A1 CK1, CK1a, CK1alpha, CKIa, CKIalpha ENSG00000113712 Casein kinase 1, alpha 1 5 149492197-149551552 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB016680, HPA051334 Uncertain Approved Cytosol Expressed in all parathyroid gland: 230.2 -HMGXB3 HMGX3, KIAA0194, SMF ENSG00000113716 HMG box domain containing 3 5 150000046-150053142 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA005967 Approved Nucleoli Tissue enriched 11 parathyroid gland: 278.2 prostate: 26.2 -ERGIC1 ERGIC-32, ERGIC32, KIAA1181, NET24 ENSG00000113719 Endoplasmic reticulum-golgi intermediate compartment 1 5 172834275-172952685 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018666, HPA018900 Supported Validated Nucleoplasm
Vesicles Expressed in all prostate: 238.4 -PDGFRB CD140b, JTK12, PDGFR, PDGFR1 ENSG00000113721 Platelet-derived growth factor receptor, beta polypeptide 5 150113837-150155872 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB003842, CAB018144, HPA028499 Approved Approved Vesicles
Cytosol Mixed gallbladder: 194.6 -CDX1 ENSG00000113722 Caudal type homeobox 1 5 150166795-150184558 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA055196 Supported Group enriched 9 colon: 132.2;duodenum: 66.3;rectum: 137.0;small intestine: 107.0 appendix: 12.7 -ATP6V0E1 ATP6H, ATP6V0E, M9.2 ENSG00000113732 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 5 172983757-173035445 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all epididymis: 758.5 -BNIP1 Nip1, SEC20 ENSG00000113734 BCL2/adenovirus E1B 19kDa interacting protein 1 5 173144442-173164387 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008009, HPA008149 Supported Supported Endoplasmic reticulum Expressed in all testis: 26.9 -STC2 STC-2 ENSG00000113739 Stanniocalcin 2 5 173314713-173329503 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045372 Uncertain Approved Endoplasmic reticulum Tissue enhanced 0 breast: 162.1 placenta: 33.0 -CPEB4 KIAA1673 ENSG00000113742 Cytoplasmic polyadenylation element binding protein 4 5 173888280-173961976 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038394 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all parathyroid gland: 117.4 -HRH2 ENSG00000113749 Histamine receptor H2 5 175658030-175686242 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA013770 Approved Tissue enhanced 0 bone marrow: 26.4 placenta: 17.9 -DBN1 D0S117E ENSG00000113758 Drebrin 1 5 177456608-177474401 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051452, HPA056940 Supported Supported Plasma membrane
Actin filaments Expressed in all cerebral cortex: 83.2 -ZNF346 JAZ, Zfp346 ENSG00000113761 Zinc finger protein 346 5 177022696-177081189 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018485 Approved Validated Nucleus Expressed in all thyroid gland: 18.0 -UNC5A KIAA1976, UNC5H1 ENSG00000113763 Unc-5 netrin receptor A 5 176810477-176880895 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071450 Approved Plasma membrane
Cytosol Group enriched 22 adrenal gland: 10.4;cerebral cortex: 35.5 lymph node: 1.0 -EHHADH ECHD ENSG00000113790 Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 3 185190624-185281990 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036401, HPA042021 Supported Group enriched 7 kidney: 147.7;liver: 173.2 duodenum: 22.0 -CNTN3 BIG-1, PANG ENSG00000113805 Contactin 3 (plasmacytoma associated) 3 74262568-74521140 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003341 Approved Tissue enhanced 0 cerebral cortex: 12.4 fallopian tube: 11.9 -SMC4 CAP-C, hCAP-C, SMC4L1 ENSG00000113810 Structural maintenance of chromosomes 4 3 160399274-160434962 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029449, CAB055509 Approved Supported Nuclear speckles
Cytosol Mixed testis: 54.9 -SELK ENSG00000113811 Selenoprotein K 3 53884410-53891988 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA008196 Uncertain Approved Nucleoplasm
Cytosol Expressed in all epididymis: 74.5 -ACTR8 INO80N ENSG00000113812 ARP8 actin-related protein 8 homolog (yeast) 3 53867066-53882202 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065236 Supported Nucleus
Centrosome Expressed in all testis: 39.3 -TBCCD1 FLJ10560 ENSG00000113838 TBCC domain containing 1 3 186546073-186570543 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Expressed in all testis: 35.4 -TIMMDC1 C3orf1, FLJ22597 ENSG00000113845 Translocase of inner mitochondrial membrane domain containing 1 3 119498532-119525090 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053214, HPA055846 Uncertain Validated Nucleus
Mitochondria Expressed in all thyroid gland: 31.5 -CRBN MRT2, MRT2A ENSG00000113851 Cereblon 3 3148992-3179710 Disease related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045910 Approved Approved Nucleoli Expressed in all testis: 86.2 -KNG1 BDK, BK, KNG ENSG00000113889 Kininogen 1 3 186717276-186743954 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001616, HPA001645, CAB009809 Supported Group enriched 946 kidney: 518.0;liver: 1860.7 rectum: 1.2 -HRG HPRG, HRGP ENSG00000113905 Histidine-rich glycoprotein 3 186660216-186678240 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050269, HPA054598 Supported Tissue enriched 84 liver: 2687.8 kidney: 31.9 -BCL6 BCL5, BCL6A, LAZ3, ZBTB27, ZNF51 ENSG00000113916 B-cell CLL/lymphoma 6 3 187721377-187745727 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB000307, HPA004899, HPA050645 Supported Validated Nucleoplasm
Golgi apparatus Expressed in all adipose tissue: 112.8 -HGD AKU, HGO ENSG00000113924 Homogentisate 1,2-dioxygenase 3 120628173-120682571 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047374, HPA052359 Supported Approved Nucleus
Nucleoli Tissue enhanced 0 kidney: 174.2;liver: 322.8 gallbladder: 87.5 -CLDN16 HOMG3, PCLN1 ENSG00000113946 Claudin 16 3 190322541-190412143 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA056020 Supported Tissue enriched 6 kidney: 51.3 thyroid gland: 8.7 -ARL6 BBS3, RP55 ENSG00000113966 ADP-ribosylation factor-like 6 3 97764521-97801242 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019361 Approved Approved Nucleoplasm
Vesicles Mixed parathyroid gland: 19.2 -NPHP3 CFAP31, FLJ30691, FLJ36696, KIAA2000, MKS7, NPH3, SLSN3 ENSG00000113971 Nephronophthisis 3 (adolescent) 3 132680609-132722442 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009150 Uncertain Mixed endometrium: 15.9 -CD86 B7-2, B7.2, CD28LG2 ENSG00000114013 CD86 molecule 3 122055366-122121139 CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004319 Uncertain Tissue enhanced 0 appendix: 49.1 spleen: 32.9 -AMOTL2 LCCP ENSG00000114019 Angiomotin like 2 3 134355874-134375479 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063027 Approved Cell Junctions
Centrosome Mixed adipose tissue: 76.4 -NIT2 ENSG00000114021 Nitrilase family, member 2 3 100334701-100361635 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036999 Approved Supported Centrosome
Cytosol Mixed kidney: 18.9 -FAM162A C3orf28, E2IG5 ENSG00000114023 Family with sequence similarity 162, member A 3 122384176-122412334 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035856, HPA058113 Approved Validated Mitochondria
Cytosol Expressed in all rectum: 165.0 -OGG1 HMMH, HOGG1, MUTM, OGH1 ENSG00000114026 8-oxoguanine DNA glycosylase 3 9749944-9788219 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027514, CAB047301 Approved Validated Nucleoplasm Expressed in all lymph node: 31.0 -KPNA1 IPOA5, NPI-1, RCH2, SRP1 ENSG00000114030 Karyopherin alpha 1 (importin alpha 5) 3 122421949-122514945 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053627, HPA063426 Supported Validated Nucleus
Cytosol Expressed in all cerebral cortex: 39.5 -PCCB ENSG00000114054 Propionyl CoA carboxylase, beta polypeptide 3 136250306-136337896 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036939, HPA036940 Supported Expressed in all liver: 102.6 -UBE3A ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A ENSG00000114062 Ubiquitin protein ligase E3A 15 25333728-25439056 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009723, HPA039410, HPA040380 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 88.7 -ARMC8 DKFZP434A043, GID5, HSPC056, VID28 ENSG00000114098 Armadillo repeat containing 8 3 138187248-138298389 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036996, HPA044869 Approved Approved Nucleoplasm
Vesicles
Cytosol Expressed in all bone marrow: 38.2 -CEP70 BITE, FLJ13036 ENSG00000114107 Centrosomal protein 70kDa 3 138494344-138594538 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036941, HPA036942 Supported Uncertain Nucleoplasm
Cytosol Expressed in all testis: 123.1 -RBP2 CRABP-II, CRBP2, CRBPII, RBPC2 ENSG00000114113 Retinol binding protein 2, cellular 3 139452884-139480747 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035866 Supported Approved Golgi apparatus Group enriched 207 duodenum: 2824.3;small intestine: 2085.7 lung: 11.8 -RBP1 CRABP-I, CRBP, CRBP1, CRBPI, RBPC ENSG00000114115 Retinol binding protein 1, cellular 3 139517434-139539829 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007338, CAB018603, CAB019276 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 fallopian tube: 627.1;ovary: 1294.2 adrenal gland: 378.0 -SLC25A36 FLJ10618, PNC2 ENSG00000114120 Solute carrier family 25 (pyrimidine nucleotide carrier), member 36 3 140941830-140979933 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027036 Approved Approved Nucleus
Mitochondria
Cytosol Expressed in all parathyroid gland: 68.3 -GRK7 GPRK7 ENSG00000114124 G protein-coupled receptor kinase 7 3 141778148-141818490 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected testis: 0.2 -RNF7 CKBBP1, ROC2, SAG ENSG00000114125 Ring finger protein 7 3 141738204-141747560 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036995 Approved Supported Nucleoplasm Expressed in all adrenal gland: 84.7 -TFDP2 Dp-2 ENSG00000114126 Transcription factor Dp-2 (E2F dimerization partner 2) 3 141944428-142149544 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018396 Supported Supported Nucleus
Vesicles Expressed in all testis: 127.0 -XRN1 SEP1 ENSG00000114127 5'-3' exoribonuclease 1 3 142306607-142448062 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035005, HPA035006 Approved Supported Plasma membrane
Cytosol Expressed in all parathyroid gland: 21.9 -KAT2B GCN5, GCN5L, P/CAF, PCAF ENSG00000114166 K(lysine) acetyltransferase 2B 3 20040023-20154404 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004526, HPA055839 Supported Approved Nucleus Expressed in all parathyroid gland: 83.6 -BCHE CHE1, CHE2, E1 ENSG00000114200 Butyrylcholinesterase 3 165772904-165837472 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001560 Supported Tissue enhanced 0 liver: 264.1 endometrium: 66.8 -SERPINI2 MEPI, PANCPIN, PI14, TSA2004 ENSG00000114204 Serpin peptidase inhibitor, clade I (pancpin), member 2 3 167441789-167479004 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 48 pancreas: 288.1 fallopian tube: 6.0 -PDCD10 CCM3, TFAR15 ENSG00000114209 Programmed cell death 10 3 167683298-167734939 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027095 Approved Expressed in all testis: 80.5 -LRRC31 FLJ23259 ENSG00000114248 Leucine rich repeat containing 31 3 169839179-169869930 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037548 Uncertain Group enriched 5 colon: 18.5;duodenum: 9.1;rectum: 24.7;small intestine: 11.2;stomach: 9.8 liver: 2.8 -WNT5A hWNT5A ENSG00000114251 Wingless-type MMTV integration site family, member 5A 3 55465715-55490539 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 endometrium: 46.3 urinary bladder: 36.5 -PFKFB4 ENSG00000114268 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 3 48517684-48562015 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047719, HPA066058 Uncertain Approved Nucleoli Tissue enhanced 0 testis: 31.7 small intestine: 23.2 -COL7A1 EBD1, EBDCT, EBR1 ENSG00000114270 Collagen, type VII, alpha 1 3 48564073-48595267 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016357, HPA042420 Supported Tissue enriched 6 skin: 114.9 endometrium: 20.0 -FGF12 FGF12B, FHF1 ENSG00000114279 Fibroblast growth factor 12 3 192139395-192767764 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071557 Approved Nucleoplasm
Cytosol Tissue enhanced 0 adrenal gland: 46.9;cerebral cortex: 52.5;heart muscle: 94.9 spleen: 16.4 -PRKAR2A PRKAR2 ENSG00000114302 Protein kinase, cAMP-dependent, regulatory, type II, alpha 3 48744597-48847846 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005023, HPA038268 Uncertain Supported Golgi apparatus
Vesicles
Microtubule organizing center Expressed in all testis: 123.7 -HES1 bHLHb39, FLJ20408, HES-1, Hes1, HRY ENSG00000114315 Hes family bHLH transcription factor 1 3 194136145-194138732 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA050504 Supported Nucleoplasm Mixed thyroid gland: 97.6 -USP4 UNP, Unph ENSG00000114316 Ubiquitin specific peptidase 4 (proto-oncogene) 3 49277831-49340712 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018499 Approved Supported Plasma membrane
Cytosol Expressed in all testis: 56.7 -ACAP2 CENTB2, CNT-B2, KIAA0041 ENSG00000114331 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 3 195274736-195443078 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034807, HPA034808 Supported Approved Endosomes Expressed in all thyroid gland: 34.1 -ECT2 ARHGEF31 ENSG00000114346 Epithelial cell transforming 2 3 172750682-172821474 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053261 Supported Nucleus Mixed testis: 29.1 -GNAT1 CSNBAD3 ENSG00000114349 Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 3 50191612-50196516 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045393 Supported Tissue enhanced 0 testis: 1.4 cerebral cortex: 0.3 -GNAI2 GIP, GNAI2B ENSG00000114353 Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3 50226292-50259355 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007704 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all spleen: 329.9 -TFG FLJ36137, SPG57, TF6 ENSG00000114354 TRK-fused gene 3 100709331-100748966 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019473, HPA052206 Approved Approved Vesicles
Cytosol Expressed in all parathyroid gland: 161.6 -USP9Y DFFRY ENSG00000114374 Ubiquitin specific peptidase 9, Y-linked Y 12701231-12860839 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057687 Uncertain Vesicles Tissue enhanced 0 prostate: 10.1 epididymis: 6.7 -HYAL1 FUS2, HYAL-1, LUCA1, NAT6 ENSG00000114378 Hyaluronoglucosaminidase 1 3 50299889-50312381 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002112 Uncertain Tissue enhanced 0 liver: 71.0;spleen: 70.4 kidney: 43.3 -TUSC2 C3orf11, FUS1, PAP, PDAP2 ENSG00000114383 Tumor suppressor candidate 2 3 50320027-50328251 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030116 Approved Vesicles
Cytosol Expressed in all cerebral cortex: 42.2 -NPRL2 NPR2, NPR2L, TUSC4 ENSG00000114388 NPR2-like, GATOR1 complex subunit 3 50347330-50351091 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038196, HPA038197 Approved Supported Cytosol Expressed in all parathyroid gland: 13.5 -RPL24 L24 ENSG00000114391 Ribosomal protein L24 3 101681091-101686782 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051653 Approved Validated Endoplasmic reticulum
Cytosol Expressed in all ovary: 2886.8 -CYB561D2 101F6, TSP10 ENSG00000114395 Cytochrome b561 family, member D2 3 50350695-50358460 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042817 Uncertain Expressed in all epididymis: 28.3 -C3orf14 HT021 ENSG00000114405 Chromosome 3 open reading frame 14 3 62318973-62336213 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048286 Approved Approved Plasma membrane
Cytosol Mixed breast: 61.4 -FXR1 ENSG00000114416 Fragile X mental retardation, autosomal homolog 1 3 180868141-180982753 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018246, HPA055475 Approved Validated Cytosol Expressed in all skeletal muscle: 276.6 -CBLB Cbl-b, RNF56 ENSG00000114423 Cbl proto-oncogene B, E3 ubiquitin protein ligase 3 105655461-105869552 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018327, HPA019880 Approved Supported Nucleoplasm
Cytosol Expressed in all lymph node: 28.4 -BBX HBP2, HSPC339, MDS001 ENSG00000114439 Bobby sox homolog (Drosophila) 3 107522936-107811324 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006049, HPA050646 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 115.3 -IFT57 ESRRBL1, FLJ10147, HIPPI, MHS4R2 ENSG00000114446 Intraflagellar transport 57 3 108160812-108222570 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035514, HPA035515 Supported Approved Nuclear speckles
Mitochondria
Cytosol Mixed testis: 66.7 -GNB4 ENSG00000114450 Guanine nucleotide binding protein (G protein), beta polypeptide 4 3 179396089-179451590 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018383, CAB018737, HPA040736 Supported Approved Plasma membrane Mixed skin: 37.8 -HHLA2 B7-H5, B7H7, B7y ENSG00000114455 HERV-H LTR-associating 2 3 108296490-108378285 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055478 Approved Group enriched 10 colon: 89.3;duodenum: 89.6;gallbladder: 46.3;rectum: 92.1;small intestine: 146.8 stomach: 9.3 -IQCG CFAP122, DKFZp434B227, DRC9 ENSG00000114473 IQ motif containing G 3 197889075-197960142 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042787 Approved Actin filaments
Cytosol Group enriched 6 fallopian tube: 83.0;testis: 78.7 lung: 13.9 -GBE1 ENSG00000114480 Glucan (1,4-alpha-), branching enzyme 1 3 81489699-81762161 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038073, HPA038074, HPA038075 Supported Supported Nucleoplasm
Cytosol Expressed in all adipose tissue: 79.3 -MORC1 CT33, MORC, ZCW6 ENSG00000114487 MORC family CW-type zinc finger 1 3 108958239-109118142 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036413 Supported Tissue enriched 69 testis: 29.6 epididymis: 0.4 -UMPS ENSG00000114491 Uridine monophosphate synthetase 3 124730366-124749273 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036178, HPA036179 Uncertain Supported Cytosol Mixed parathyroid gland: 3.5 -NCBP2 Cbc2, CBP20, NIP1 ENSG00000114503 Nuclear cap binding protein subunit 2, 20kDa 3 196935402-196942597 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044850, HPA062483 Supported Validated Nucleoplasm Expressed in all cerebral cortex: 79.5 -SNX4 ATG24B ENSG00000114520 Sorting nexin 4 3 125446644-125520197 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005709 Uncertain Expressed in all thyroid gland: 75.1 -C3orf52 FLJ23186, TTMP ENSG00000114529 Chromosome 3 open reading frame 52 3 112086335-112131004 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008119, HPA011968 Uncertain Tissue enhanced 0 skin: 23.2 stomach: 16.7 -FRMD4B GRSP1, KIAA1013 ENSG00000114541 FERM domain containing 4B 3 69169990-69542583 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009705 Uncertain Supported Mixed spleen: 44.2 -SLC41A3 FLJ20473 ENSG00000114544 Solute carrier family 41, member 3 3 126006355-126101561 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045847 Approved Supported Plasma membrane Expressed in all testis: 79.0 -ROPN1B ENSG00000114547 Rhophilin associated tail protein 1B 3 125969144-125983454 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052530 Approved Tissue enriched 8 testis: 370.5 breast: 45.0 -PLXNA1 NOV, PLXN1 ENSG00000114554 Plexin A1 3 126988594-127037392 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007499, CAB012483 Uncertain Supported Nucleus
Cytosol Tissue enhanced 0 parathyroid gland: 42.7 skin: 16.8 -ATP6V1A ATP6A1, ATP6V1A1, VA68, Vma1, VPP2 ENSG00000114573 ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 3 113747019-113812056 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006910, HPA035083, HPA035084 Approved Supported Nucleus
Vesicles
Cytosol Expressed in all cerebral cortex: 151.8 -ABTB1 BPOZ, Btb3, BTBD21, EF1ABP ENSG00000114626 Ankyrin repeat and BTB (POZ) domain containing 1 3 127672935-127680920 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035022, HPA035023 Uncertain Supported Nucleoli
Cytosol Expressed in all spleen: 51.1 -PODXL2 endoglycan, PODLX2 ENSG00000114631 Podocalyxin-like 2 3 127629181-127672809 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB024934, HPA042265 Approved Approved Golgi apparatus
Vesicles Tissue enhanced 0 cerebral cortex: 77.3 testis: 35.9 -UPK1B TSPAN20, UPK1 ENSG00000114638 Uroplakin 1B 3 119173517-119205153 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031799, HPA031800 Supported Tissue enhanced 0 stomach: 33.2;urinary bladder: 37.5 tonsil: 16.0 -CSPG5 NGC ENSG00000114646 Chondroitin sulfate proteoglycan 5 (neuroglycan C) 3 47562239-47580792 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049529, HPA067818, HPA071779 Supported Approved Nucleoplasm
Mitochondria Tissue enriched 56 cerebral cortex: 157.1 testis: 2.8 -KLHL18 FLJ13703, KIAA0795 ENSG00000114648 Kelch-like family member 18 3 47282917-47346816 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035027, HPA035028 Approved Approved Nucleoplasm
Nuclear bodies Expressed in all skin: 14.2 -SCAP KIAA0199 ENSG00000114650 SREBF chaperone 3 47413694-47477126 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004713 Approved Expressed in all adrenal gland: 67.3 -EFCC1 C3orf73, CCDC48, FLJ12057 ENSG00000114654 EF-hand and coiled-coil domain containing 1 3 129001629-129040742 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042798, HPA050888 Uncertain Tissue enhanced 0 lung: 4.9 spleen: 3.6 -KIAA1257 ENSG00000114656 KIAA1257 3 128909866-129002690 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042811, HPA048445 Uncertain Group enriched 10 placenta: 9.7;testis: 35.0 fallopian tube: 2.2 -NEK11 FLJ23495 ENSG00000114670 NIMA-related kinase 11 3 131026850-131350465 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016908 Approved Supported Nucleoplasm Tissue enhanced 0 fallopian tube: 34.3 testis: 27.8 -MRPL3 MRL3, RPML3 ENSG00000114686 Mitochondrial ribosomal protein L3 3 131462212-131502983 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043665, HPA060132 Approved Expressed in all thyroid gland: 107.2 -PLSCR4 ENSG00000114698 Phospholipid scramblase 4 3 146192339-146251179 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002276 Approved Approved Nucleoplasm
Nuclear bodies Expressed in all placenta: 79.5 -HEMK1 MTQ1 ENSG00000114735 HemK methyltransferase family member 1 3 50569152-50596168 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034701, HPA034702 Uncertain Expressed in all parathyroid gland: 31.6 -CISH CIS, CIS-1, G18, SOCS ENSG00000114737 Cytokine inducible SH2-containing protein 3 50606490-50611831 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB034039, HPA040812 Approved Approved Microtubules
Cytokinetic bridge Mixed thyroid gland: 42.9 -MAPKAPK3 3pK, MAPKAP3 ENSG00000114738 Mitogen-activated protein kinase-activated protein kinase 3 3 50611520-50649297 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058275 Supported Nucleoplasm Expressed in all heart muscle: 117.7 -ACVR2B ActR-IIB ENSG00000114739 Activin A receptor, type IIB 3 38453851-38493142 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007398, CAB025115 Approved Approved Nucleus
Nuclear bodies
Cytosol Mixed parathyroid gland: 6.3 -WDR48 KIAA1449, P80, SPG60 ENSG00000114742 WD repeat domain 48 3 39051998-39096671 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038421, HPA058015 Approved Supported Vesicles Expressed in all testis: 72.3 -COMMD2 HSPC042 ENSG00000114744 COMM domain containing 2 3 149738470-149752499 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044190 Uncertain Approved Nucleoplasm
Nuclear bodies Expressed in all thyroid gland: 23.4 -GORASP1 FLJ23443, GOLPH5, GRASP65, P65 ENSG00000114745 Golgi reassembly stacking protein 1, 65kDa 3 39096659-39108363 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056283 Supported Supported Golgi apparatus Expressed in all cervix: 36.7 -PEX5L PEX5R, PXR2, TRIP8b ENSG00000114757 Peroxisomal biogenesis factor 5-like 3 179794958-180037053 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058026 Approved Group enriched 9 cerebral cortex: 67.7;parathyroid gland: 93.0 testis: 8.8 -RRP9 RNU3IP2, U3-55K ENSG00000114767 Ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 3 51933430-51941941 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038798 Uncertain Supported Nucleus Expressed in all fallopian tube: 18.7 -ABCC5 EST277145, MOAT-C, MRP5, SMRP ENSG00000114770 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3 183919934-184018015 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044067, HPA052295 Uncertain Supported Nucleus
Plasma membrane
Cell Junctions Expressed in all stomach: 72.0 -AADAC CES5A1, DAC ENSG00000114771 Arylacetamide deacetylase 3 151814037-151828488 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002911 Approved Group enriched 5 adrenal gland: 151.1;duodenum: 187.8;liver: 385.8;small intestine: 220.5 stomach: 43.9 -ABHD14B CIB, MGC15429 ENSG00000114779 Abhydrolase domain containing 14B 3 51968510-51983409 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036444, HPA036642 Supported Supported Nucleus
Nucleoli
Cytosol Expressed in all thyroid gland: 90.5 -EIF1B GC20 ENSG00000114784 Eukaryotic translation initiation factor 1B 3 40309684-40312424 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all heart muscle: 229.2 -ABHD14A-ACY1 ENSG00000114786 ABHD14A-ACY1 readthrough 3 51975050-51989183 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA036174, HPA036175, HPA038153 Uncertain Uncertain Vesicles Not detected cervix: 0.2 -ARHGEF26 DKFZP434D146, SGEF ENSG00000114790 Rho guanine nucleotide exchange factor (GEF) 26 3 154121003-154257827 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017722, HPA049195 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Mixed lung: 15.6 -KLHL24 DRE1, FLJ20059 ENSG00000114796 Kelch-like family member 24 3 183635568-183684477 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056337 Uncertain Expressed in all parathyroid gland: 73.1 -PLCH1 DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3 ENSG00000114805 Phospholipase C, eta 1 3 155375580-155745067 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036176, HPA057978 Uncertain Validated Vesicles Tissue enhanced 0 testis: 20.6 fallopian tube: 12.8 -VIPR1 HVR1, RDC1, VPAC1, VPAC1R ENSG00000114812 Vasoactive intestinal peptide receptor 1 3 42489299-42537573 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA026777 Approved Tissue enhanced 0 lung: 60.0 duodenum: 35.4 -DNAH1 DNAHC1, HDHC7, HL-11, HL11, XLHSRF-1 ENSG00000114841 Dynein, axonemal, heavy chain 1 3 52316319-52400491 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036805, HPA036806 Uncertain Mixed testis: 7.8 -SSR3 TRAPG ENSG00000114850 Signal sequence receptor, gamma (translocon-associated protein gamma) 3 156540140-156555184 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014906 Approved Approved Uncertain Cytosol Expressed in all cervix: 203.5 -ZBTB47 DKFZp434N0615, KIAA1190, ZNF651 ENSG00000114853 Zinc finger and BTB domain containing 47 3 42653684-42665854 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA074057 Approved Nucleoplasm Expressed in all cerebral cortex: 48.0 -TNNC1 TNNC ENSG00000114854 Troponin C type 1 (slow) 3 52451102-52454070 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002450, HPA044848, HPA056897 Supported Approved Nucleoplasm
Actin filaments
Mitochondria Group enriched 15 heart muscle: 4358.3;skeletal muscle: 7106.5 esophagus: 385.2 -NKTR p104 ENSG00000114857 Natural killer cell triggering receptor 3 42600614-42648741 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022120, HPA051576 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 24.3 -CLCN2 ClC-2, CLC2, EJM6 ENSG00000114859 Chloride channel, voltage-sensitive 2 3 184346185-184361651 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009397, HPA014545, HPA024108 Approved Approved Cytosol Mixed testis: 22.0 -FOXP1 12CC4, hFKH1B, HSPC215, QRF1 ENSG00000114861 Forkhead box P1 3 70954693-71583989 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003876, CAB011501 Supported Validated Nucleoplasm Expressed in all ovary: 39.5 -EIF4G1 EIF4F, EIF4G, p220, PARK18 ENSG00000114867 Eukaryotic translation initiation factor 4 gamma, 1 3 184314495-184335358 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB014774, HPA028487, HPA043866 Approved Validated Cytosol Expressed in all parathyroid gland: 206.5 -SPCS1 HSPC033, SPC1, SPC12, YJR010C-A ENSG00000114902 Signal peptidase complex subunit 1 3 52704955-52711146 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046091, HPA055273 Supported Approved Golgi apparatus
Vesicles Expressed in all testis: 215.4 -NEK4 NRK2, pp12301, STK2 ENSG00000114904 NIMA-related kinase 4 3 52708449-52770949 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015750 Approved Approved Nucleoplasm Expressed in all testis: 83.9 -SLC4A3 AE3, SLC2C ENSG00000114923 Solute carrier family 4 (anion exchanger), member 3 2 219627327-219641980 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA063498 Approved Nucleoplasm Group enriched 6 cerebral cortex: 30.1;heart muscle: 125.7;ovary: 47.6 testis: 10.9 -INO80D FLJ20309 ENSG00000114933 INO80 complex subunit D 2 205993721-206086303 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043976 Approved Expressed in all testis: 30.1 -EEF1B2 ENSG00000114942 Eukaryotic translation elongation factor 1 beta 2 2 206159585-206162928 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012477, HPA035029 Supported Approved Nucleoli fibrillar center
Cytosol Expressed in all breast: 1028.1 -ADAM23 MDC3 ENSG00000114948 ADAM metallopeptidase domain 23 2 206443539-206621130 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012130, CAB033276 Uncertain Group enriched 6 cerebral cortex: 55.7;parathyroid gland: 132.9 heart muscle: 16.4 -DGUOK dGK ENSG00000114956 Deoxyguanosine kinase 2 73926826-73958961 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034766, HPA057246 Approved Expressed in all testis: 56.4 -MOB1A C2orf6, FLJ10788, FLJ11595, Mats1, MOB1, Mob4B, MOBK1B, MOBKL1B ENSG00000114978 MOB kinase activator 1A 2 74152528-74178898 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047088, HPA071690 Supported Approved Nucleus
Nucleoli
Cytosol Expressed in all lymph node: 109.0 -KANSL3 FLJ10081, KIAA1310, NSL3, Rcd1 ENSG00000114982 KAT8 regulatory NSL complex subunit 3 2 96593170-96642787 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035017, HPA035018, HPA041280 Approved Validated Nucleus Expressed in all testis: 28.2 -LMAN2L DKFZp564L2423, VIPL ENSG00000114988 Lectin, mannose-binding 2-like 2 96705929-96740064 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026600 Approved Mixed fallopian tube: 27.7 -RTKN B5 ENSG00000114993 Rhotekin 2 74425836-74442422 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030259 Approved Approved Nucleoplasm
Mitochondria Mixed cerebral cortex: 46.8 -TTL MGC46235 ENSG00000114999 Tubulin tyrosine ligase 2 112482154-112541739 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA066819 Approved Nucleoplasm
Vesicles Mixed cerebral cortex: 4.5 -IL1A IL-1A, IL1, IL1-ALPHA, IL1F1 ENSG00000115008 Interleukin 1, alpha 2 112773915-112784590 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 esophagus: 12.8;testis: 18.6 tonsil: 7.7 -CCL20 CKb4, exodus-1, LARC, MIP-3a, SCYA20, ST38 ENSG00000115009 Chemokine (C-C motif) ligand 20 2 227813842-227817564 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 gallbladder: 270.5;tonsil: 161.2 urinary bladder: 86.7 -PIKFYVE FAB1, KIAA0981, MGC40423, p235, PIKfyve, PIP5K, PIP5K3, ZFYVE29 ENSG00000115020 Phosphoinositide kinase, FYVE finger containing 2 208266267-208358751 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042604 Uncertain Uncertain Nuclear speckles Expressed in all testis: 25.7 -KCNIP3 calsenilin, CSEN, DREAM, KCHIP3 ENSG00000115041 Kv channel interacting protein 3, calsenilin 2 95297304-95386083 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA066717, HPA069797 Approved Uncertain Vesicles Tissue enhanced 0 cerebral cortex: 40.7;parathyroid gland: 43.4 thyroid gland: 27.9 -FAHD2A CGI-105 ENSG00000115042 Fumarylacetoacetate hydrolase domain containing 2A 2 95402721-95416616 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042145, HPA044987, CAB045971, CAB045972 Supported Expressed in all liver: 52.6 -NCL C23 ENSG00000115053 Nucleolin 2 231453531-231483641 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004210, HPA023981 Supported Validated Nucleus
Nucleoli Expressed in all parathyroid gland: 440.8 -ACTR1B Arp1B, CTRN2 ENSG00000115073 ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 2 97655963-97664107 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047443 Approved Microtubules Expressed in all parathyroid gland: 80.5 -SLC35F5 FLJ22004 ENSG00000115084 Solute carrier family 35, member F5 2 113705011-113756823 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA034828, HPA049229 Uncertain Uncertain Plasma membrane Expressed in all thyroid gland: 65.7 -ZAP70 SRK, STD, ZAP-70 ENSG00000115085 Zeta-chain (TCR) associated protein kinase 70kDa 2 97713560-97739862 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002625, HPA003134 Supported Tissue enhanced 0 appendix: 37.7;lymph node: 65.2;spleen: 38.3 tonsil: 16.9 -ACTR3 ARP3 ENSG00000115091 ARP3 actin-related protein 3 homolog (yeast) 2 113889960-113962596 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005085, HPA047016, HPA051683 Approved Expressed in all lymph node: 340.2 -STEAP3 dudlin-2, STMP3, TSAP6 ENSG00000115107 STEAP family member 3, metalloreductase 2 119223831-119265652 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050510 Uncertain Approved Nucleoli
Cytosol Tissue enhanced 0 parathyroid gland: 190.8 liver: 53.0 -EPB41L5 BE37, FLJ12957, KIAA1548, YMO1, YRT ENSG00000115109 Erythrocyte membrane protein band 4.1 like 5 2 120013005-120179119 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037563, HPA037564 Uncertain Supported Plasma membrane Mixed testis: 56.3 -TFCP2L1 CRTR1, LBP-9 ENSG00000115112 Transcription factor CP2-like 1 2 121216587-121285207 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA029708 Uncertain Supported Nucleoli fibrillar center Tissue enhanced 0 kidney: 48.7 thyroid gland: 45.6 -SF3B6 CGI-110, Ht006, P14, SAP14a, SF3B14a ENSG00000115128 Splicing factor 3b, subunit 6, 14kDa 2 24067584-24076443 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034829, HPA034830 Supported Supported Nucleoplasm Expressed in all thyroid gland: 152.6 -TP53I3 PIG3 ENSG00000115129 Tumor protein p53 inducible protein 3 2 24077433-24085861 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017479, HPA022012, HPA028742 Supported Supported Vesicles Expressed in all esophagus: 97.5 -DNAJC27 RabJS, RBJ ENSG00000115137 DnaJ (Hsp40) homolog, subfamily C, member 27 2 24943636-24972094 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA036815, HPA036816 Uncertain Supported Cytosol Tissue enhanced 0 testis: 39.3 cerebral cortex: 8.7 -POMC ACTH, CLIP, LPH, MSH, NPP, POC ENSG00000115138 Proopiomelanocortin 2 25160853-25168903 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB002762, HPA046135, HPA063644 Supported Tissue enhanced 0 testis: 6.8 pancreas: 5.2 -STAM2 Hbp ENSG00000115145 Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 2 152116801-152175992 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035528, HPA035529 Supported Supported Nucleoplasm
Vesicles
Cytosol Expressed in all thyroid gland: 22.7 -OTOF DFNB6, DFNB9, FER1L2 ENSG00000115155 Otoferlin 2 26457203-26558698 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007502, HPA012410 Uncertain Tissue enhanced 0 bone marrow: 4.3 cerebral cortex: 1.1 -GPD2 ENSG00000115159 Glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 2 156435290-156613735 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008012, HPA045506 Supported Expressed in all parathyroid gland: 44.9 -CENPA CenH3, CENP-A ENSG00000115163 Centromere protein A 2 26764289-26801067 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008371, HPA073086 Supported Supported Nucleus Tissue enhanced 0 lymph node: 7.5 tonsil: 6.7 -CYTIP B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP ENSG00000115165 Cytohesin 1 interacting protein 2 157414619-157488961 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007191 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 lymph node: 103.1;tonsil: 106.0 appendix: 95.3 -ACVR1 ACVR1A, ACVRLK2, ALK2, SKR1 ENSG00000115170 Activin A receptor, type I 2 157736444-157875862 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007505 Approved Expressed in all thyroid gland: 73.9 -TANC1 KIAA1728, ROLSB ENSG00000115183 Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 2 158968634-159232659 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036750 Approved Mixed skin: 25.0 -SLC30A3 ZNT3 ENSG00000115194 Solute carrier family 30 (zinc transporter), member 3 2 27253684-27275817 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060505, HPA067637 Approved Approved Nucleus
Nucleoli
Vesicles
Cytosol Group enriched 14 cerebral cortex: 36.7;epididymis: 65.2;testis: 43.6 heart muscle: 3.4 -MPV17 SYM1 ENSG00000115204 MpV17 mitochondrial inner membrane protein 2 27309492-27325680 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 84.1 -GTF3C2 KIAA0011, TFIIIC110 ENSG00000115207 General transcription factor IIIC, polypeptide 2, beta 110kDa 2 27325849-27357034 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035836 Uncertain Expressed in all parathyroid gland: 55.0 -EIF2B4 DKFZP586J0119, EIF-2B, EIF2B, EIF2Bdelta ENSG00000115211 Eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 2 27364352-27370486 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032234, HPA039993 Uncertain Approved Nuclear membrane
Actin filaments Expressed in all testis: 51.8 -NRBP1 BCON3, MADM, MUDPNP, NRBP ENSG00000115216 Nuclear receptor binding protein 1 2 27427790-27442259 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029527, CAB033078 Supported Supported Cytosol Expressed in all testis: 125.5 -ITGB6 ENSG00000115221 Integrin, beta 6 2 160099666-160271888 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023626, CAB073536 Approved Uncertain Nucleoplasm
Cell Junctions
Centrosome Tissue enhanced 0 lung: 66.9 urinary bladder: 31.3 -FNDC4 FLJ22362, FRCP1 ENSG00000115226 Fibronectin type III domain containing 4 2 27491883-27495245 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051804, HPA063581 Uncertain Approved Nucleoplasm
Aggresome
Cytosol Tissue enhanced 0 adrenal gland: 72.9 cerebral cortex: 36.0 -ITGA4 CD49D ENSG00000115232 Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 2 181457202-181536187 Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064041 Approved Golgi apparatus
Vesicles Tissue enhanced 0 spleen: 68.6 appendix: 51.2 -PSMD14 pad1, POH1, Rpn11 ENSG00000115233 Proteasome 26S subunit, non-ATPase 14 2 161308038-161411717 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002114, HPA003828 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 56.3 -SNX17 KIAA0064 ENSG00000115234 Sorting nexin 17 2 27370496-27377533 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043867 Supported Supported Vesicles Expressed in all fallopian tube: 96.8 -ASB3 ASB-3 ENSG00000115239 Ankyrin repeat and SOCS box containing 3 2 53532672-53787610 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003940 Uncertain Expressed in all cerebral cortex: 28.3 -PPM1G PP2CG, PP2Cgamma ENSG00000115241 Protein phosphatase, Mg2+/Mn2+ dependent, 1G 2 27381194-27409687 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035530, HPA035531 Supported Validated Nucleoplasm Expressed in all testis: 336.6 -PDE1A ENSG00000115252 Phosphodiesterase 1A, calmodulin-dependent 2 182140036-182523192 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA022151 Approved Approved Nucleoplasm Tissue enhanced 0 thyroid gland: 76.2 testis: 62.5 -REEP6 C19orf32, DP1L1, FLJ25383 ENSG00000115255 Receptor accessory protein 6 19 1490747-1497927 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003895, HPA048015 Approved Supported Endoplasmic reticulum Group enriched 8 adrenal gland: 48.4;duodenum: 170.8;liver: 76.3;small intestine: 170.5;testis: 181.6 prostate: 17.0 -PCSK4 DKFZp434B217, MGC34749, PC4, SPC5 ENSG00000115257 Proprotein convertase subtilisin/kexin type 4 19 1481428-1490752 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA005572 Uncertain Tissue enriched 9 testis: 41.3 fallopian tube: 4.7 -GCG GLP1, GLP2, GRPP ENSG00000115263 Glucagon 2 162142873-162152404 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000040, HPA036760, HPA036761 Supported Uncertain Golgi apparatus
Vesicles Tissue enhanced 0 pancreas: 346.2;rectum: 139.2;small intestine: 126.0 colon: 70.8 -APC2 APCL ENSG00000115266 Adenomatosis polyposis coli 2 19 1446302-1473244 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA078002 Approved Cytokinetic bridge
Midbody ring
Cytosol Tissue enriched 21 cerebral cortex: 70.7 adrenal gland: 3.3 -IFIH1 Hlcd, IDDM19, MDA-5, MDA5 ENSG00000115267 Interferon induced with helicase C domain 1 2 162267079-162318703 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002656 Approved Mixed spleen: 31.6 -RPS15 MGC111130, RIG, S15 ENSG00000115268 Ribosomal protein S15 19 1438358-1440494 Cancer-related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054510, HPA057793 Supported Approved Endoplasmic reticulum
Cytosol Expressed in all ovary: 1335.1 -GCA GCL ENSG00000115271 Grancalcin, EF-hand calcium binding protein 2 162318840-162371595 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035033, HPA035034 Supported Supported Plasma membrane
Cytosol Tissue enhanced 0 bone marrow: 214.9 appendix: 90.2 -INO80B hIes2, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4 ENSG00000115274 INO80 complex subunit B 2 74455023-74457960 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042717 Supported Nucleus
Plasma membrane
Cytosol Expressed in all parathyroid gland: 42.0 -MOGS CWH41, DER7, GCS1 ENSG00000115275 Mannosyl-oligosaccharide glucosidase 2 74461057-74465410 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011322, HPA011969 Approved Validated Endoplasmic reticulum Expressed in all duodenum: 64.8 -TTC31 FLJ12788 ENSG00000115282 Tetratricopeptide repeat domain 31 2 74483073-74494886 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041783 Uncertain Approved Nucleoplasm
Cytosol Mixed parathyroid gland: 11.6 -NDUFS7 CI-20, FLJ45860, FLJ46880, PSST ENSG00000115286 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 19 1383527-1395589 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skeletal muscle: 96.8 duodenum: 41.9 -PCGF1 MGC10882, NSPC1, RNF68 ENSG00000115289 Polycomb group ring finger 1 2 74505043-74508580 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011356, HPA069156 Supported Validated Nucleoplasm Mixed fallopian tube: 9.2 -GRB14 ENSG00000115290 Growth factor receptor-bound protein 14 2 164492812-164621848 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022294, HPA035052, HPA035053 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 epididymis: 6.0;kidney: 6.1;liver: 6.6 testis: 4.3 -CLIP4 FLJ21069, RSNL2 ENSG00000115295 CAP-GLY domain containing linker protein family, member 4 2 29097705-29189643 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043366, HPA056246 Uncertain Validated Vesicles Expressed in all thyroid gland: 55.6 -TLX2 Enx, HOX11L1, NCX, Tlx2 ENSG00000115297 T-cell leukemia homeobox 2 2 74513463-74517147 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA040969, HPA062254 Uncertain Approved Nucleoplasm Tissue enhanced 0 adrenal gland: 2.7 testis: 0.8 -SPTBN1 ENSG00000115306 Spectrin, beta, non-erythrocytic 1 2 54456285-54671445 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012685, HPA013149 Supported Approved Golgi apparatus Expressed in all parathyroid gland: 369.9 -AUP1 ENSG00000115307 Ancient ubiquitous protein 1 2 74526645-74529939 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007674 Approved Approved Nucleoplasm
Vesicles Expressed in all parathyroid gland: 57.1 -RTN4 ASY, KIAA0886, NOGO, NSP-CL ENSG00000115310 Reticulon 4 2 54972187-55112621 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005388, HPA023977 Supported Validated Endoplasmic reticulum Expressed in all cerebral cortex: 638.6 -HTRA2 OMI, PARK13, PRSS25 ENSG00000115317 HtrA serine peptidase 2 2 74529377-74533348 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004004, HPA006602, HPA027366 Uncertain Supported Mitochondria Mixed spleen: 9.2 -LOXL3 ENSG00000115318 Lysyl oxidase-like 3 2 74532414-74555690 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035281 Approved Mixed placenta: 20.6 -DOK1 p62dok ENSG00000115325 Docking protein 1, 62kDa (downstream of tyrosine kinase 1) 2 74549026-74557554 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004224, HPA048561 Approved Supported Cytosol Mixed appendix: 9.0 -GALNT3 GalNAc-T3, HFTC, HHS ENSG00000115339 Polypeptide N-acetylgalactosaminyltransferase 3 2 165747591-165794682 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007613 Supported Supported Golgi apparatus Mixed stomach: 86.2 -POLE4 p12 ENSG00000115350 Polymerase (DNA-directed), epsilon 4, accessory subunit 2 74958492-74970128 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054979, HPA071815 Approved Approved Nucleus
Cytosol Expressed in all cervix: 12.7 -TACR1 NK1R, NKIR, SPR, TAC1R ENSG00000115353 Tachykinin receptor 1 2 75046463-75199700 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA074573 Approved Tissue enhanced 0 cervix, uterine: 7.3 fallopian tube: 4.7 -CCDC88A APE, FLJ10392, GIV, GRDN, HkRP1, KIAA1212 ENSG00000115355 Coiled-coil domain containing 88A 2 55287842-55419921 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038101, HPA038102 Supported Expressed in all testis: 116.9 -ACADL ACAD4, LCAD ENSG00000115361 Acyl-CoA dehydrogenase, long chain 2 210187939-210225491 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011990 Supported Supported Tissue enhanced 0 thyroid gland: 31.9 prostate: 25.1 -EVA1A FAM176A, FLJ13391, TMEM166 ENSG00000115363 Eva-1 homolog A (C. elegans) 2 75469302-75569722 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA008055 Approved Supported Vesicles
Plasma membrane Tissue enhanced 0 liver: 98.5 lung: 31.1 -MRPL19 KIAA0104, MRP-L15, RLX1, RPML15 ENSG00000115364 Mitochondrial ribosomal protein L19 2 75646783-75690851 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046805, HPA056622 Approved Supported Mitochondria Expressed in all parathyroid gland: 65.3 -LANCL1 GPR69A, p40 ENSG00000115365 LanC lantibiotic synthetase component C-like 1 (bacterial) 2 210431249-210477652 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034994 Approved Approved Microtubules Expressed in all cerebral cortex: 153.7 -WDR75 FLJ12519, NET16, UTP17 ENSG00000115368 WD repeat domain 75 2 189441433-189475565 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038199 Approved Approved Nucleoplasm Expressed in all endometrium: 39.3 -EFEMP1 DHRD, FBLN3, FBNL, MTLV, S1-5 ENSG00000115380 EGF containing fibulin-like extracellular matrix protein 1 2 55865967-55924139 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016368, HPA049806, HPA070841, HPA071588 Supported Uncertain Mitochondria Mixed placenta: 485.9 -REG1A PSP, PSPS, PSPS1, PTP, REG ENSG00000115386 Regenerating islet-derived 1 alpha 2 79120362-79123419 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025138, HPA045549, HPA045579 Supported Group enriched 9 duodenum: 7327.1;pancreas: 10865.2;small intestine: 4712.3 stomach: 839.5 -FANCL FAAP43, FLJ10335, PHF9, Pog ENSG00000115392 Fanconi anemia, complementation group L 2 58159243-58241372 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033842, HPA036685, HPA036686 Supported Approved Nuclear bodies
Vesicles Expressed in all adrenal gland: 44.8 -FN1 CIG, FINC, GFND2, LETS, MSF ENSG00000115414 Fibronectin 1 2 215360440-215436172 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000126, HPA027066 Supported Tissue enhanced 0 placenta: 4245.7 lung: 1168.8 -STAT1 ISGF-3, STAT91 ENSG00000115415 Signal transducer and activator of transcription 1, 91kDa 2 190964358-191020960 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000931, HPA000982, CAB004049 Approved Validated Nucleoplasm
Cytosol Expressed in all lymph node: 196.3 -GLS GLS1, KIAA0838 ENSG00000115419 Glutaminase 2 190880827-190965552 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036223 Supported Supported Mitochondria Expressed in all kidney: 330.7 -PAPOLG FLJ12972 ENSG00000115421 Poly(A) polymerase gamma 2 60756230-60802085 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017795, HPA035349, HPA035350 Approved Validated Nucleoplasm Mixed thyroid gland: 22.1 -DNAH6 Dnahc6, DNHL1, FLJ37357, HL-2 ENSG00000115423 Dynein, axonemal, heavy chain 6 2 84516455-84819589 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036391 Supported Tissue enhanced 0 fallopian tube: 9.7;testis: 5.8 parathyroid gland: 3.6 -PECR HSA250303, SDR29C1, TERP ENSG00000115425 Peroxisomal trans-2-enoyl-CoA reductase 2 215996329-216082955 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021593, HPA022539 Approved Supported Peroxisomes Expressed in all liver: 82.9 -UNC50 GMH1, UNCL, URP ENSG00000115446 Unc-50 homolog (C. elegans) 2 98608579-98618515 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027009 Approved Expressed in all thyroid gland: 105.7 -IGFBP2 IBP2 ENSG00000115457 Insulin-like growth factor binding protein 2, 36kDa 2 216632828-216664436 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077723 Approved Endoplasmic reticulum Expressed in all seminal vesicle: 276.7 -ELMOD3 DFNB88, FLJ21977, RBED1, RBM29 ENSG00000115459 ELMO/CED-12 domain containing 3 2 85354394-85391752 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA012126 Approved Approved Nucleoplasm
Mitochondria Expressed in all adipose tissue: 11.1 -IGFBP5 ENSG00000115461 Insulin-like growth factor binding protein 5 2 216672105-216695525 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009216, HPA040514 Approved Approved Vesicles Tissue enhanced 0 cervix, uterine: 2362.7;ovary: 1642.0 fallopian tube: 939.6 -USP34 KIAA0570, KIAA0729 ENSG00000115464 Ubiquitin specific peptidase 34 2 61187463-61470769 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025815, HPA070764 Uncertain Approved Nucleus Expressed in all testis: 61.1 -EFHD1 FLJ13612 ENSG00000115468 EF-hand domain family, member D1 2 232606057-232682781 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049331, HPA056959 Supported Supported Nucleoli fibrillar center
Golgi apparatus Tissue enhanced 0 breast: 225.2 kidney: 176.1 -KCNJ13 Kir1.4, Kir7.1, LCA16 ENSG00000115474 Potassium channel, inwardly rectifying subfamily J, member 13 2 232766464-232776568 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 parathyroid gland: 25.4;small intestine: 114.2 thyroid gland: 12.5 -CCT4 Cctd ENSG00000115484 Chaperonin containing TCP1, subunit 4 (delta) 2 61868089-61888804 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029349 Supported Supported Nucleoplasm
Cytosol Expressed in all testis: 133.5 -GGCX VKCFD1 ENSG00000115486 Gamma-glutamyl carboxylase 2 85544723-85561547 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018284 Approved Expressed in all liver: 61.2 -NEU2 SIAL2 ENSG00000115488 Sialidase 2 (cytosolic sialidase) 2 233032672-233035057 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022336 Uncertain Tissue enriched 13 skin: 1.4 breast: 0.1 -EHBP1 KIAA0903, NACSIN ENSG00000115504 EH domain binding protein 1 2 62673851-63046487 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035468, HPA035469 Supported Supported Plasma membrane
Cytosol Expressed in all testis: 67.5 -OTX1 ENSG00000115507 Orthodenticle homeobox 1 2 63050057-63057836 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB012341, HPA052122 Approved Uncertain Nuclear speckles
Cytosol Tissue enhanced 0 cerebral cortex: 1.7;skin: 6.1 prostate: 0.9 -TXNDC9 APACD ENSG00000115514 Thioredoxin domain containing 9 2 99318982-99340702 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031844, HPA031845, HPA031846 Approved Validated Cytosol Expressed in all thyroid gland: 36.2 -COQ10B FLJ13448 ENSG00000115520 Coenzyme Q10B 2 197453423-197475308 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046057 Approved Approved Cytosol Expressed in all adrenal gland: 49.9 -GNLY D2S69E, LAG-2, LAG2, NKG5, TLA519 ENSG00000115523 Granulysin 2 85685175-85698854 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025186, HPA058021 Supported Tissue enhanced 0 bone marrow: 153.1;endometrium: 113.5;spleen: 114.5 lung: 51.2 -SF3B1 Hsh155, Prp10, PRPF10, SAP155, SF3b155 ENSG00000115524 Splicing factor 3b, subunit 1, 155kDa 2 197389784-197435091 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050275 Approved Validated Nuclear speckles Expressed in all endometrium: 345.5 -ST3GAL5 SIAT9, SIATGM3S, ST3GalV ENSG00000115525 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2 85839144-85889014 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034708, HPA040425, HPA068928 Uncertain Approved Vesicles Mixed thyroid gland: 72.2 -CHST10 HNK-1ST ENSG00000115526 Carbohydrate sulfotransferase 10 2 100391860-100417656 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA012884, HPA051545 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 46.6 endometrium: 19.3 -PDCL3 VIAF1 ENSG00000115539 Phosducin-like 3 2 100562690-100576735 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018469, HPA027094 Approved Validated Nucleus
Cytosol Expressed in all smooth muscle: 39.8 -MOB4 2C4D, CGI-95, DKFZP564M112, MOB3, MOBKL3, PHOCN, PREI3 ENSG00000115540 MOB family member 4, phocein 2 197515571-197553699 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034082, HPA044125 Approved Expressed in all adrenal gland: 80.0 -HSPE1 CPN10, EPF, GroES, HSP10 ENSG00000115541 Heat shock 10kDa protein 1 2 197499994-197503457 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017366, HPA038755, HPA048272 Supported Expressed in all adrenal gland: 653.6 -KDM3A JHMD2A, JMJD1, JMJD1A, KIAA0742, TSGA ENSG00000115548 Lysine (K)-specific demethylase 3A 2 86440647-86492716 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055543, HPA065162 Validated Nucleoplasm Expressed in all testis: 93.2 -PLCD4 ENSG00000115556 Phospholipase C, delta 4 2 218607765-218637184 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB009914, HPA038139, HPA038140 Approved Approved Nuclear membrane
Plasma membrane
Cytosol Tissue enhanced 0 skeletal muscle: 38.4 testis: 10.0 -CHMP3 CGI-149, NEDF, VPS24 ENSG00000115561 Charged multivesicular body protein 3 2 86503431-86563479 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015673 Approved Expressed in all endometrium: 113.5 -ZNF142 KIAA0236, pHZ-49 ENSG00000115568 Zinc finger protein 142 2 218637916-218659655 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049594 Uncertain Approved Nucleus
Nucleoli fibrillar center Expressed in all parathyroid gland: 15.0 -IL1R2 CD121b, IL1RB ENSG00000115590 Interleukin 1 receptor, type II 2 101991844-102028544 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027597, HPA027598 Approved Mixed appendix: 51.2 -PRKAG3 ENSG00000115592 Protein kinase, AMP-activated, gamma 3 non-catalytic subunit 2 218822383-218832086 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 18 skeletal muscle: 23.9 esophagus: 1.3 -SMYD1 BOP, KMT3D, ZMYND22 ENSG00000115593 SET and MYND domain containing 1 2 88067780-88113387 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062282 Supported Group enriched 9 heart muscle: 98.8;skeletal muscle: 170.8;smooth muscle: 38.0 parathyroid gland: 11.4 -IL1R1 CD121A, D2S1473, IL1R, IL1RA ENSG00000115594 Interleukin 1 receptor, type I 2 102064544-102179874 Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001237, HPA005823, CAB007779, HPA029560 Approved Validated Vesicles Expressed in all cervix: 244.6 -WNT6 ENSG00000115596 Wingless-type MMTV integration site family, member 6 2 218859821-218874233 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052031 Uncertain Tissue enhanced 0 placenta: 2.9 spleen: 1.5 -IL1RL2 IL1R-rp2, IL1RRP2 ENSG00000115598 Interleukin 1 receptor-like 2 2 102186973-102240002 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA015485 Uncertain Tissue enhanced 0 skin: 15.5 parathyroid gland: 8.3 -IL1RL1 DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1 ENSG00000115602 Interleukin 1 receptor-like 1 2 102311502-102352037 Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007406, HPA007917 Uncertain Approved Vesicles Tissue enriched 12 placenta: 286.6 gallbladder: 23.8 -IL18R1 CD218a, IL-1Rrp, IL1RRP ENSG00000115604 Interleukin 18 receptor 1 2 102311529-102398775 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007615 Approved Approved Mitochondria Mixed placenta: 14.3 -IL18RAP AcPL, CD218b ENSG00000115607 Interleukin 18 receptor accessory protein 2 102418689-102452565 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB025270 Supported Tissue enhanced 0 bone marrow: 71.0 appendix: 17.3 -SLC9A2 NHE2 ENSG00000115616 Solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 2 102619707-102711318 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035121, HPA035122 Approved Approved Cell Junctions Tissue enhanced 0 colon: 20.9;rectum: 23.7;stomach: 25.8 testis: 10.6 -FHL2 DRAL, SLIM3 ENSG00000115641 Four and a half LIM domains 2 2 105357712-105438513 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005922, HPA006028, CAB008368 Supported Validated Actin filaments
Focal adhesion sites Expressed in all ovary: 657.3 -MLPH exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a ENSG00000115648 Melanophilin 2 237485428-237555318 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014685 Uncertain Mixed prostate: 102.1 -CNPPD1 C2orf24, CGI-57 ENSG00000115649 Cyclin Pas1/PHO80 domain containing 1 2 219171897-219178106 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049303 Uncertain Expressed in all parathyroid gland: 86.9 -UXS1 FLJ23591, SDR6E1, UGD ENSG00000115652 UDP-glucuronate decarboxylase 1 2 106093303-106194339 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008825 Uncertain Expressed in all placenta: 75.5 -ABCB6 EST45597, MTABC3, umat ENSG00000115657 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2 219209768-219218990 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046723, HPA058011 Approved Validated Nucleoplasm
Golgi apparatus
Plasma membrane
Mitochondria
Cytosol Expressed in all testis: 32.5 -STK16 MPSK, PKL12 ENSG00000115661 Serine/threonine kinase 16 2 219245455-219250337 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029450 Approved Approved Cytosol Expressed in all testis: 28.6 -SLC5A7 CHT1, hCHT ENSG00000115665 Solute carrier family 5 (sodium/choline cotransporter), member 7 2 107986523-108013994 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA046105 Approved Nuclear bodies
Cell Junctions
Intermediate filaments Mixed thyroid gland: 2.0 -HDLBP HBP, VGL ENSG00000115677 High density lipoprotein binding protein 2 241227264-241317061 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004189, CAB026457 Supported Supported Cytosol Expressed in all testis: 364.5 -PPP1R7 sds22 ENSG00000115685 Protein phosphatase 1, regulatory subunit 7 2 241149576-241183652 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034500, HPA034501 Approved Approved Nucleoli Expressed in all testis: 286.4 -PASK KIAA0135, PASKIN, STK37 ENSG00000115687 PAS domain containing serine/threonine kinase 2 241106099-241150264 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016450, HPA021079 Uncertain Supported Cytosol Tissue enhanced 0 testis: 25.6 lymph node: 16.3 -STK25 SOK1, YSK1 ENSG00000115694 Serine/threonine kinase 25 2 241492674-241509730 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047147 Uncertain Expressed in all skeletal muscle: 168.2 -TPO TPX ENSG00000115705 Thyroid peroxidase 2 1374223-1543711 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA007987, CAB009587 Supported Tissue enriched 101 thyroid gland: 1811.8 spleen: 17.9 -PROC ENSG00000115718 Protein C (inactivator of coagulation factors Va and VIIIa) 2 127418427-127429246 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005550, CAB016721, CAB016792 Supported Tissue enriched 12 liver: 139.9 kidney: 12.0 -ID2 bHLHb26, GIG8 ENSG00000115738 Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2 8678845-8684453 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA027612 Approved Nucleoplasm
Nuclear bodies
Centrosome Tissue enriched 5 parathyroid gland: 1947.2 thyroid gland: 357.9 -TAF1B RAF1B, RAFI63, SL1, TAFI63 ENSG00000115750 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 2 9843354-9934416 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071254 Supported Nucleus
Nucleoli Mixed parathyroid gland: 23.5 -HPCAL1 BDR1, HLP2, VILIP-3 ENSG00000115756 Hippocalcin-like 1 2 10302889-10427617 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043245 Approved Expressed in all lung: 80.8 -ODC1 ODC ENSG00000115758 Ornithine decarboxylase 1 2 10439968-10448504 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001536, CAB035996 Approved Approved Plasma membrane
Cytosol Expressed in all testis: 240.7 -BIRC6 BRUCE ENSG00000115760 Baculoviral IAP repeat containing 6 2 32357028-32618899 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA074409, HPA074738 Supported Golgi apparatus
Vesicles Mixed parathyroid gland: 30.8 -NOL10 FLJ14075, PQBP5 ENSG00000115761 Nucleolar protein 10 2 10570766-10689987 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035286, HPA043075 Approved Supported Nucleoli Expressed in all testis: 27.8 -PLEKHB2 EVT2, FLJ20783 ENSG00000115762 Pleckstrin homology domain containing, family B (evectins) member 2 2 131104847-131353709 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all cerebral cortex: 125.6 -GORASP2 GOLPH6, GRASP55, GRS2 ENSG00000115806 Golgi reassembly stacking protein 2, 55kDa 2 170928464-170967129 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035274, HPA035275 Supported Validated Golgi apparatus Expressed in all epididymis: 41.5 -STRN SG2NA ENSG00000115808 Striatin, calmodulin binding protein 2 36843640-36966472 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017286 Approved Approved Nucleoplasm
Cytosol Expressed in all esophagus: 23.9 -CEBPZ CBF2, CTF2 ENSG00000115816 CCAAT/enhancer binding protein (C/EBP), zeta 2 37201612-37231713 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052065 Uncertain Approved Nucleus
Vesicles Expressed in all testis: 68.2 -PRKD3 EPK2, PRKCN ENSG00000115825 Protein kinase D3 2 37250502-37324808 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029529 Uncertain Supported Nucleoplasm
Cytosol Expressed in all testis: 44.2 -DCAF17 C2orf37, FLJ13096 ENSG00000115827 DDB1 and CUL4 associated factor 17 2 171434217-171485052 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053339, HPA055040 Uncertain Supported Nucleoplasm Expressed in all thyroid gland: 17.0 -QPCT GCT, QC ENSG00000115828 Glutaminyl-peptide cyclotransferase 2 37344574-37373322 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008406 Uncertain Approved Cytosol Tissue enhanced 0 adrenal gland: 159.5;epididymis: 119.5 skin: 41.1 -RAB3GAP1 KIAA0066, RAB3GAP, RAB3GAP130, WARBM1 ENSG00000115839 RAB3 GTPase activating protein subunit 1 (catalytic) 2 135052265-135176394 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034494, HPA034495 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 55.8 -SLC25A12 Aralar ENSG00000115840 Solute carrier family 25 (aspartate/glutamate carrier), member 12 2 171784370-171999859 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035333, HPA035334 Supported Mixed skeletal muscle: 55.3 -RMDN2 FAM82A, FAM82A1, FLJ32954, RMD2 ENSG00000115841 Regulator of microtubule dynamics 2 2 37923187-38067142 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034705, HPA034706 Approved Supported Cytosol Expressed in all adrenal gland: 69.2 -DLX2 TES-1 ENSG00000115844 Distal-less homeobox 2 2 172099439-172102900 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056965 Approved Nuclear speckles Not detected cerebral cortex: 0.8 -LCT ENSG00000115850 Lactase 2 135787840-135837180 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007408 Uncertain Group enriched 640 duodenum: 229.4;small intestine: 146.2 lymph node: 0.2 -DARS ENSG00000115866 Aspartyl-tRNA synthetase 2 135906677-135986100 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020451, HPA029804, HPA029805 Supported Validated Cytosol Expressed in all thyroid gland: 90.6 -SRSF7 9G8, AAG3, HSSG1, RBM37, SFRS7, ZCCHC20, ZCRB2 ENSG00000115875 Serine/arginine-rich splicing factor 7 2 38743599-38751494 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043850, HPA056926 Supported Validated Nucleoplasm Expressed in all testis: 99.3 -SDC1 CD138, SDC, SYND1, syndecan ENSG00000115884 Syndecan 1 2 20200797-20225433 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002424, HPA006185 Approved Approved Focal adhesion sites Tissue enhanced 0 esophagus: 251.7;skin: 288.6 liver: 144.9 -PLCL1 PLC-L, PLCE, PLCL, PPP1R127, PRIP ENSG00000115896 Phospholipase C-like 1 2 197804702-198572581 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031849 Approved Mixed kidney: 34.0 -SLC1A4 ASCT1, SATT ENSG00000115902 Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2 64988477-65023865 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034963, HPA034964 Approved Validated Microtubule organizing center
Centrosome Expressed in all cerebral cortex: 79.3 -SOS1 GF1, GINGF, HGF ENSG00000115904 Son of sevenless homolog 1 (Drosophila) 2 38981396-39124345 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB005396, HPA012613 Uncertain Uncertain Nucleus
Nucleoli
Cytosol Expressed in all parathyroid gland: 40.3 -KYNU ENSG00000115919 Kynureninase 2 142877498-143055832 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031686 Approved Mixed liver: 45.7 -WIPF1 WASPIP, WIP ENSG00000115935 WAS/WASL interacting protein family, member 1 2 174559572-174682916 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003739, CAB009737, HPA070706 Supported Approved Plasma membrane
Cytosol Expressed in all lymph node: 159.5 -ORC2 ORC2L ENSG00000115942 Origin recognition complex, subunit 2 2 200908973-200963680 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003693, HPA073881 Supported Supported Nucleoplasm
Cytosol Mixed testis: 38.1 -COX7A2L COX7AR, COX7RP, EB1, SIG81 ENSG00000115944 Cytochrome c oxidase subunit VIIa polypeptide 2 like 2 42333546-42425088 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059124, CAB073545 Validated Nucleoli
Mitochondria Expressed in all adrenal gland: 255.6 -PNO1 KHRBP1, RRP20 ENSG00000115946 Partner of NOB1 homolog 2 68157844-68176238 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056928 Supported Nucleus
Nucleoli Expressed in all thyroid gland: 20.7 -ORC4 HsORC4, ORC4L, Orc4p ENSG00000115947 Origin recognition complex, subunit 4 2 147930397-148021604 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015124, HPA064562 Approved Supported Nucleus
Nucleoli Expressed in all testis: 28.9 -PLEK P47 ENSG00000115956 Pleckstrin 2 68365173-68397453 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031838 Approved Tissue enhanced 0 bone marrow: 371.7 lymph node: 144.4 -RND3 ARHE, Rho8, RhoE ENSG00000115963 Rho family GTPase 3 2 150468195-150539011 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060504 Uncertain Mixed esophagus: 170.2 -ATF2 CRE-BP1, CREB2, HB16, TREB7 ENSG00000115966 Activating transcription factor 2 2 175072250-175168382 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003769, HPA022134 Supported Validated Nucleoplasm Expressed in all thyroid gland: 53.7 -THADA FLJ21877, GITA, KIAA1767 ENSG00000115970 Thyroid adenoma associated 2 43230836-43596046 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035191, HPA035192 Uncertain Approved Cytosol Expressed in all parathyroid gland: 26.4 -AAK1 DKFZp686K16132, KIAA1048 ENSG00000115977 AP2 associated kinase 1 2 69457997-69674349 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017931, HPA020289 Approved Supported Plasma membrane
Cytosol Tissue enriched 6 parathyroid gland: 382.6 thyroid gland: 59.1 -TRAK2 ALS2CR3, CALS-C, GRIF-1, KIAA0549, MILT2, OIP98 ENSG00000115993 Trafficking protein, kinesin binding 2 2 201377207-201451611 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015827, HPA062163 Uncertain Approved Nucleoplasm
Nuclear bodies
Vesicles Expressed in all thyroid gland: 55.7 -C2orf42 FLJ20558 ENSG00000115998 Chromosome 2 open reading frame 42 2 70149880-70248615 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031840, HPA031841, HPA031842 Supported Validated Nucleus Tissue enriched 6 testis: 109.3 fallopian tube: 18.4 -TIA1 ENSG00000116001 TIA1 cytotoxic granule-associated RNA binding protein 2 70209444-70248660 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056961 Supported Nucleoplasm
Cytosol Expressed in all endometrium: 112.3 -PCYOX1 KIAA0908, PCL1 ENSG00000116005 Prenylcysteine oxidase 1 2 70257386-70281191 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035193 Approved Expressed in all parathyroid gland: 138.9 -KISS1R AXOR12, GPR54, HOT7T175 ENSG00000116014 KISS1 receptor 19 917287-921015 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA071913 Supported Vesicles
Plasma membrane Tissue enriched 5 cerebral cortex: 1.2 placenta: 0.2 -EPAS1 bHLHe73, HIF2A, HLF, MOP2, PASD2 ENSG00000116016 Endothelial PAS domain protein 1 2 46293667-46386703 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031200 Approved Nucleoplasm
Cytosol Expressed in all placenta: 636.7 -ARID3A BRIGHT, DRIL1 ENSG00000116017 AT rich interactive domain 3A (BRIGHT-like) 19 925781-975934 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004793 Approved Supported Nucleoplasm
Vesicles
Cytosol Tissue enhanced 0 placenta: 33.3 testis: 9.7 -SUMO1 GMP1, OFC10, PIC1, SMT3C, SMT3H3, SUMO-1, UBL1 ENSG00000116030 Small ubiquitin-like modifier 1 2 202206180-202238608 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004269, HPA056956 Supported Supported Nucleus
Nuclear membrane
Nucleoli
Nuclear bodies Expressed in all thyroid gland: 170.7 -CD207 CLEC4K, Langerin ENSG00000116031 CD207 molecule, langerin 2 70830214-70835822 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB002222, HPA011216 Supported Uncertain Cytosol Tissue enriched 5 skin: 104.2 esophagus: 19.4 -GRIN3B GluN3B ENSG00000116032 Glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 19 1000419-1009732 FDA approved drug targets, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 2.1;spleen: 1.2 lung: 0.7 -VAX2 DRES93 ENSG00000116035 Ventral anterior homeobox 2 2 70900590-70933446 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009708 Approved Nuclear speckles Tissue enhanced 0 cerebral cortex: 3.3 breast: 0.7 -ATP6V1B1 ATP6B1, RTA1B, VATB, Vma2, VPP3 ENSG00000116039 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 2 70935882-70965406 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009523, HPA031847 Supported Approved Nucleus
Nuclear membrane Group enriched 10 breast: 16.0;cervix, uterine: 47.5;fallopian tube: 20.8;kidney: 64.5;placenta: 27.6;salivary gland: 67.0 skin: 4.2 -NFE2L2 NRF2 ENSG00000116044 Nuclear factor, erythroid 2-like 2 2 177227595-177392697 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002990, CAB020317, HPA043438 Supported Approved Nucleus
Plasma membrane
Cytosol Expressed in all esophagus: 267.9 -MSH6 GTBP ENSG00000116062 MutS homolog 6 2 47695530-47810101 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009091, HPA028376, HPA028446 Supported Supported Nucleoplasm
Golgi apparatus
Vesicles Expressed in all ovary: 74.4 -PLEKHA3 FAPP1 ENSG00000116095 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 2 178480468-178516462 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034496, HPA034497 Approved Validated Golgi apparatus Mixed testis: 15.1 -SPR SDR38C1 ENSG00000116096 Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 2 72887360-72892158 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039505 Uncertain Supported Nucleoplasm
Cytosol Mixed parathyroid gland: 49.1 -EPHA4 Hek8, TYRO1 ENSG00000116106 EPH receptor A4 2 221418027-221574202 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB028368 Supported Tissue enhanced 0 cerebral cortex: 41.8 testis: 22.3 -PARD3B ALS2CR19, PAR3beta, Par3L ENSG00000116117 Par-3 family cell polarity regulator beta 2 204545793-205620162 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035283 Approved Supported Cell Junctions Mixed parathyroid gland: 13.1 -FARSB FARSLB, FRSB, PheHB ENSG00000116120 Phenylalanyl-tRNA synthetase, beta subunit 2 222570536-222656337 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036677, HPA036678, HPA061398 Supported Supported Nucleus
Cytosol Expressed in all testis: 34.3 -ALMS1 KIAA0328 ENSG00000116127 Alstrom syndrome protein 1 2 73385758-73610793 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043200 Supported Approved Cytosol Tissue enhanced 0 testis: 32.4 ovary: 9.1 -BCL9 ENSG00000116128 B-cell CLL/lymphoma 9 1 147541412-147626216 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020274 Approved Approved Nucleoplasm
Nuclear bodies Mixed fallopian tube: 26.3 -PRRX1 PHOX1, PMX1 ENSG00000116132 Paired related homeobox 1 1 170662728-170739419 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051084 Uncertain Supported Nucleus
Nucleoli Mixed cervix: 135.2 -DHCR24 DCE, KIAA0018, seladin-1 ENSG00000116133 24-dehydrocholesterol reductase 1 54849633-54887218 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB037247, HPA063005 Approved Expressed in all adrenal gland: 1100.8 -DNAJC16 KIAA0962 ENSG00000116138 DnaJ (Hsp40) homolog, subfamily C, member 16 1 15526813-15592379 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043643 Approved Approved Vesicles Expressed in all kidney: 20.8 -MARK1 MARK, PAR-1C ENSG00000116141 MAP/microtubule affinity-regulating kinase 1 1 220528183-220664461 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007421, HPA008061 Uncertain Mixed cerebral cortex: 21.1 -TNR ENSG00000116147 Tenascin R 1 175315194-175743770 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022343, HPA027134, HPA027150, HPA029859 Supported Tissue enriched 38 cerebral cortex: 70.8 adrenal gland: 1.8 -MORN1 FLJ13941 ENSG00000116151 MORN repeat containing 1 1 2321253-2391707 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA005858, HPA070703 Uncertain Approved Nucleus
Mitochondria Tissue enhanced 0 fallopian tube: 17.6 testis: 12.2 -GPX7 FLJ14777, GPX6, NPGPx ENSG00000116157 Glutathione peroxidase 7 1 52602372-52609051 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025829 Approved Nucleoli Expressed in all placenta: 41.7 -CACYBP S100A6BP, SIP ENSG00000116161 Calcyclin binding protein 1 174999163-175011715 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025753, HPA057038 Approved Validated Nucleoplasm
Cytosol Expressed in all cerebral cortex: 60.9 -SCP2 ENSG00000116171 Sterol carrier protein 2 1 52927229-53051703 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027101, HPA027135, HPA027317 Supported Validated Peroxisomes Expressed in all liver: 569.5 -TPSG1 PRSS31, TMT ENSG00000116176 Tryptase gamma 1 16 1221651-1225257 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060458 Approved Tissue enhanced 0 colon: 15.2;duodenum: 14.7;small intestine: 10.7 rectum: 9.8 -PAPPA2 PAPP-A2, PAPPE, PLAC3 ENSG00000116183 Pappalysin 2 1 176463171-176845605 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018412, HPA018430 Supported Approved Endoplasmic reticulum
Vesicles Tissue enriched 8 placenta: 82.1 cervix: 10.8 -RALGPS2 FLJ10244, FLJ25604, KIAA0351 ENSG00000116191 Ral GEF with PH domain and SH3 binding motif 2 1 178725147-178921841 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027143, HPA028328 Approved Uncertain Nucleoplasm
Cytosol Tissue enhanced 0 testis: 137.1 lymph node: 63.5 -ANGPTL1 ANG3, ANGPT3, AngY, ARP1 ENSG00000116194 Angiopoietin-like 1 1 178849705-178871052 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA009976 Approved Tissue enhanced 0 placenta: 188.3 smooth muscle: 95.5 -CEP104 CFAP256, GlyBP, KIAA0562, ROC22, RP1-286D6.4 ENSG00000116198 Centrosomal protein 104kDa 1 3812081-3857214 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010126 Approved Expressed in all parathyroid gland: 35.5 -FAM20B GXK1, KIAA0475 ENSG00000116199 Family with sequence similarity 20, member B 1 179025804-179076562 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007409 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 37.2 -TCEANC2 C1orf83, FLJ32112 ENSG00000116205 Transcription elongation factor A (SII) N-terminal and central domain containing 2 1 54053587-54112519 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046918 Uncertain Approved Nucleoplasm
Vesicles Mixed testis: 12.8 -TMEM59 C1orf8, HSPC001 ENSG00000116209 Transmembrane protein 59 1 54026681-54053504 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all fallopian tube: 642.0 -LRRC42 MGC8974 ENSG00000116212 Leucine rich repeat containing 42 1 53946077-53968168 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047458, HPA050537, HPA064581 Uncertain Validated Nucleoplasm Expressed in all thyroid gland: 38.9 -WRAP73 WDR8 ENSG00000116213 WD repeat containing, antisense to TP73 1 3630767-3652761 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026893 Uncertain Approved Nucleoplasm
Cell Junctions Expressed in all lymph node: 20.7 -NPHS2 PDCN, SRN1 ENSG00000116218 Nephrosis 2, idiopathic, steroid-resistant (podocin) 1 179550539-179575952 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037267, HPA049486 Supported Tissue enriched 79 kidney: 92.9 testis: 1.1 -MRPL37 MRP-L2, RPML2 ENSG00000116221 Mitochondrial ribosomal protein L37 1 54184041-54225464 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025767, HPA025826, HPA025951 Supported Supported Mitochondria Expressed in all fallopian tube: 61.1 -ICMT HSTE14, PCCMT, PPMT ENSG00000116237 Isoprenylcysteine carboxyl methyltransferase 1 6221193-6235972 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032024, HPA032025 Uncertain Expressed in all parathyroid gland: 45.0 -RPL22 EAP, L22 ENSG00000116251 Ribosomal protein L22 1 6181269-6209389 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 1344.6 -CHD5 ENSG00000116254 Chromodomain helicase DNA binding protein 5 1 6101793-6180123 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015809, HPA055477 Supported Supported Nucleoplasm
Nuclear speckles
Cytosol Tissue enriched 7 cerebral cortex: 42.2 testis: 6.1 -QSOX1 QSCN6 ENSG00000116260 Quiescin Q6 sulfhydryl oxidase 1 1 180154834-180204030 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042127, HPA056243 Uncertain Supported Golgi apparatus
Vesicles Expressed in all gallbladder: 234.2 -STXBP3 UNC-18C ENSG00000116266 Syntaxin binding protein 3 1 108746674-108809526 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027225 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 64.7 -PHF13 MGC43399 ENSG00000116273 PHD finger protein 13 1 6613685-6624033 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA026830 Uncertain Expressed in all testis: 58.8 -ERRFI1 GENE-33, MIG-6, RALT ENSG00000116285 ERBB receptor feedback inhibitor 1 1 8004404-8026308 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027206 Supported Cytosol Expressed in all liver: 369.0 -PARK7 DJ-1, DJ1 ENSG00000116288 Parkinson protein 7 1 7954291-7985505 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004190, CAB005870 Supported Supported Nucleus
Cytosol Expressed in all parathyroid gland: 505.2 -KIAA1324 EIG121, maba1 ENSG00000116299 KIAA1324 1 109113679-109206781 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029869, HPA070749 Supported Supported Plasma membrane Mixed cervix: 128.0 -OPRD1 ENSG00000116329 Opioid receptor, delta 1 1 28812142-28871267 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA013744 Uncertain Tissue enhanced 0 cerebral cortex: 2.6 adrenal gland: 0.8 -AMPD2 SPG63 ENSG00000116337 Adenosine monophosphate deaminase 2 1 109616104-109632051 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027137, HPA045760, HPA050590 Approved Approved Validated Cytosol Expressed in all bone marrow: 82.5 -SRSF4 SFRS4, SRP75 ENSG00000116350 Serine/arginine-rich splicing factor 4 1 29147743-29181987 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050975 Supported Supported Nuclear speckles Expressed in all placenta: 78.8 -MECR CGI-63, FASN2B, NRBF1 ENSG00000116353 Mitochondrial trans-2-enoyl-CoA reductase 1 29192873-29230942 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022018, HPA022030, HPA028740 Supported Supported Mitochondria Expressed in all cerebral cortex: 18.4 -KCNC4 C1orf30, HKSHIIIC, Kv3.4 ENSG00000116396 Potassium channel, voltage gated Shaw related subfamily C, member 4 1 110211343-110283100 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014740 Approved Approved Nucleoli
Cytosol Mixed cerebral cortex: 6.3 -EDEM3 C1orf22 ENSG00000116406 ER degradation enhancer, mannosidase alpha-like 3 1 184690231-184754913 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025754, HPA025755, HPA027297 Approved Approved Endoplasmic reticulum Expressed in all stomach: 34.4 -WDR77 MEP50, p44 ENSG00000116455 WD repeat domain 77 1 111439890-111449376 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026437, HPA026448, HPA027271 Approved Supported Nucleoplasm
Golgi apparatus
Cytosol Expressed in all fallopian tube: 161.0 -ATP5F1 ENSG00000116459 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 1 111448864-111462773 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046067, HPA057347 Supported Supported Nucleoplasm
Mitochondria Expressed in all heart muscle: 51.1 -RAP1A KREV-1, SMGP21 ENSG00000116473 RAP1A, member of RAS oncogene family 1 111542218-111716691 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 199.7 -HDAC1 GON-10, HD1, RPD3L1 ENSG00000116478 Histone deacetylase 1 1 32292086-32333635 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005017, HPA029693, CAB068191 Supported Validated Nucleoplasm Expressed in all lymph node: 140.7 -CAPZA1 ENSG00000116489 Capping protein (actin filament) muscle Z-line, alpha 1 1 112619173-112671619 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045963 Approved Expressed in all lymph node: 135.8 -S100PBP FLJ12903, S100PBPR ENSG00000116497 S100P binding protein 1 32816767-32858879 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027242, HPA027328 Approved Supported Nuclear speckles Expressed in all testis: 62.7 -RNF19B FLJ90005, IBRDC3 ENSG00000116514 Ring finger protein 19B 1 32936445-32964685 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049587 Approved Approved Cytosol Expressed in all testis: 154.8 -SCAMP3 C1orf3 ENSG00000116521 Secretory carrier membrane protein 3 1 155255979-155262430 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071167 Supported Vesicles Expressed in all parathyroid gland: 46.1 -TRIM62 DEAR1, FLJ10759 ENSG00000116525 Tripartite motif containing 62 1 33145402-33182059 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA050061 Approved Vesicles
Focal adhesion sites Mixed skin: 11.6 -ASH1L ASH1, ASH1L1, huASH1, KMT2H ENSG00000116539 Ash1 (absent, small, or homeotic)-like (Drosophila) 1 155335268-155562807 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004806 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 37.3 -DLGAP3 DAP3, SAPAP3 ENSG00000116544 Discs, large (Drosophila) homolog-associated protein 3 1 34865436-34929585 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026445 Supported Group enriched 11 cerebral cortex: 21.9;testis: 5.7 spleen: 1.2 -SFPQ PPP1R140, PSF ENSG00000116560 Splicing factor proline/glutamine-rich 1 35176378-35193148 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009886, HPA047513, HPA054689 Supported Validated Nucleoplasm Expressed in all bone marrow: 135.7 -RHOU ARHU, CDC42L1, DJ646B12.2, fJ646B12.2, FLJ10616, hG28K, WRCH-1, WRCH1 ENSG00000116574 Ras homolog family member U 1 228735077-228746669 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049592 Approved Expressed in all cerebral cortex: 62.3 -GON4L FLJ20203, GON-4, GON4 ENSG00000116580 Gon-4-like (C. elegans) 1 155749662-155859400 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006986, HPA057305, HPA074504 Uncertain Validated Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 24.6 -ARHGEF2 GEF-H1, KIAA0651, LFP40, P40 ENSG00000116584 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1 155946851-156007070 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043437 Approved Expressed in all lung: 95.3 -LAMTOR2 ENDAP, MAPBPIP, MAPKSP1AP, p14, Ragulator2, ROBLD3 ENSG00000116586 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 1 156054752-156058510 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004126 Approved Approved Nucleoplasm
Vesicles Expressed in all epididymis: 83.7 -MEF2D ENSG00000116604 Myocyte enhancer factor 2D 1 156463727-156500828 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004807, HPA007114 Supported Validated Nucleoplasm Expressed in all skeletal muscle: 55.5 -DOCK7 KIAA1771, ZIR2 ENSG00000116641 Dedicator of cytokinesis 7 1 62454726-62688368 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed testis: 25.1 -SRM SPS1, SRML1 ENSG00000116649 Spermidine synthase 1 11054584-11060024 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015746 Approved Approved Nucleoplasm
Cytosol Expressed in all appendix: 75.6 -FBXO2 Fbg1, Fbs1, FBX2, Nfb42, OCP1 ENSG00000116661 F-box protein 2 1 11648367-11655785 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005472 Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 80.8 adrenal gland: 27.8 -FBXO6 FBG2, FBS2, FBX6, Fbx6b ENSG00000116663 F-box protein 6 1 11664124-11674354 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051175 Approved Expressed in all fallopian tube: 21.2 -C1orf21 PIG13 ENSG00000116667 Chromosome 1 open reading frame 21 1 184387058-184629020 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026831 Uncertain Approved Nucleoplasm
Cytosol Mixed skin: 30.2 -SWT1 C1orf26, FLJ20121, HsSwt1 ENSG00000116668 SWT1 RNA endoribonuclease homolog 1 185157080-185291765 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA024214, HPA027334 Uncertain Approved Cytosol Tissue enriched 8 testis: 69.0 thyroid gland: 8.7 -MAD2L2 MAD2B, POLZ2, REV7 ENSG00000116670 MAD2 mitotic arrest deficient-like 2 (yeast) 1 11674480-11691650 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008110, HPA024176 Approved Supported Nucleoli
Cytosol Expressed in all testis: 73.5 -DNAJC6 KIAA0473, PARK19 ENSG00000116675 DnaJ (Hsp40) homolog, subfamily C, member 6 1 65248219-65415869 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031182, HPA054917 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enriched 10 cerebral cortex: 163.3 adrenal gland: 15.7 -LEPR CD295, OBR ENSG00000116678 Leptin receptor 1 65420652-65641559 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030899 Approved Vesicles Mixed liver: 69.9 -IVNS1ABP HSPC068, KIAA0850, KLHL39, ND1, NS-1, NS1-BP ENSG00000116679 Influenza virus NS1A binding protein 1 185296388-185317329 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003405 Approved Supported Cytosol Expressed in all bone marrow: 300.2 -KIAA2013 MGC33867, RP5-1077B9.1 ENSG00000116685 KIAA2013 1 11919591-11926428 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA052677, HPA060536 Uncertain Approved Golgi apparatus
Cytosol Expressed in all small intestine: 69.5 -MFN2 CMT2A2, CPRP1, KIAA0214, MARF ENSG00000116688 Mitofusin 2 1 11980181-12013514 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030554 Uncertain Expressed in all heart muscle: 197.9 -PRG4 bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP ENSG00000116690 Proteoglycan 4 1 186296279-186314562 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028523 Uncertain Tissue enriched 6 liver: 97.3 lung: 15.4 -MIIP FLJ12438, IIp45 ENSG00000116691 Migration and invasion inhibitory protein 1 12019466-12032045 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044948 Uncertain Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 27.5 -SMG7 C1orf16, EST1C, KIAA0250, SGA56M, SMG-7 ENSG00000116698 SMG7 nonsense mediated mRNA decay factor 1 183472216-183598246 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029350 Supported Supported Intermediate filaments
Cytosol Expressed in all testis: 122.5 -NCF2 NOXA2, p67phox ENSG00000116701 Neutrophil cytosolic factor 2 1 183555563-183590876 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002327, HPA006040, CAB022160 Supported Validated Nucleoli
Cytosol Tissue enhanced 0 bone marrow: 127.7 lung: 111.7 -PDC MEKA ENSG00000116703 Phosducin 1 186443566-186461122 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062235 Supported Not detected testis: 0.4 -SLC35D1 KIAA0260, UGTREL7 ENSG00000116704 Solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 1 66999332-67054099 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all liver: 38.5 -PLA2G4A cPLA2-alpha, PLA2G4 ENSG00000116711 Phospholipase A2, group IVA (cytosolic, calcium-dependent) 1 186828953-186988981 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010050, HPA050062, HPA054206 Approved Supported Cytosol Tissue enhanced 0 parathyroid gland: 196.9 seminal vesicle: 67.6 -GADD45A DDIT1, GADD45 ENSG00000116717 Growth arrest and DNA-damage-inducible, alpha 1 67685061-67688338 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA053420 Supported Nuclear speckles Expressed in all thyroid gland: 91.1 -PRAMEF1 ENSG00000116721 PRAME family member 1 1 12791397-12796628 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.1 -PRAMEF12 ENSG00000116726 PRAME family member 12 1 12774841-12777906 Plasma proteins, Predicted intracellular proteins No evidence No evidence No evidence HPA045286, HPA051704 Uncertain Uncertain Nucleoplasm Not detected epididymis: 0.0 -WLS C1orf139, EVI, FLJ23091, GPR177, mig-14, MRP, wls ENSG00000116729 Wntless Wnt ligand secretion mediator 1 68098473-68233120 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069520 Approved Supported Endoplasmic reticulum Expressed in all epididymis: 160.7 -PRDM2 HUMHOXY1, KMT8, MTB-ZF, RIZ, RIZ1, RIZ2 ENSG00000116731 PR domain containing 2, with ZNF domain 1 13700198-13825079 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005809 Approved Approved Nucleus
Golgi apparatus Expressed in all bone marrow: 51.3 -RGS2 G0S8 ENSG00000116741 Regulator of G-protein signaling 2 1 192809039-192812283 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013385 Approved Cytosol Expressed in all smooth muscle: 739.2 -RPE65 BCO3, LCA2, rd12, RP20 ENSG00000116745 Retinal pigment epithelium-specific protein 65kDa 1 68428822-68449959 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 2.8;prostate: 3.1;seminal vesicle: 6.1 endometrium: 1.0 -TROVE2 Ro60, SSA2 ENSG00000116747 TROVE domain family, member 2 1 193059422-193091777 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002835, HPA005142 Uncertain Approved Nucleoplasm
Cytosol Expressed in all prostate: 28.6 -AMPD1 MAD, MADA ENSG00000116748 Adenosine monophosphate deaminase 1 1 114673098-114695618 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026478, HPA028080 Supported Tissue enriched 11 skeletal muscle: 208.6 duodenum: 18.6 -UCHL5 CGI-70, INO80R, UCH37 ENSG00000116750 Ubiquitin carboxyl-terminal hydrolase L5 1 193012250-193060080 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005908, HPA006069, HPA075383 Approved Approved Approved Nucleoplasm
Mitochondria Expressed in all cerebral cortex: 43.1 -BCAS2 DAM1, Snt309, SPF27 ENSG00000116752 Breast carcinoma amplified sequence 2 1 114567557-114581639 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067881 Supported Approved Nuclear speckles
Centrosome Expressed in all thyroid gland: 70.8 -SRSF11 NET2, p54, SFRS11 ENSG00000116754 Serine/arginine-rich splicing factor 11 1 70205682-70253052 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008762 Supported Supported Nuclear speckles Expressed in all endometrium: 96.2 -CTH ENSG00000116761 Cystathionine gamma-lyase 1 70411218-70439851 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021591, HPA023300 Supported Expressed in all liver: 73.1 -AGMAT FLJ23384 ENSG00000116771 Agmatine ureohydrolase (agmatinase) 1 15572353-15585110 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026443, HPA028321 Supported Tissue enhanced 0 kidney: 157.9 liver: 36.6 -OLFML3 HNOEL-iso, OLF44 ENSG00000116774 Olfactomedin-like 3 1 113979391-114035572 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed cervix: 265.4 -TNNI3K CARK ENSG00000116783 TNNI3 interacting kinase 1 74235401-74544428 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 7 heart muscle: 38.9 testis: 5.3 -CFHR3 CFHL3, DOWN16, FHR-3, FHR3, HLF4 ENSG00000116785 Complement factor H-related 3 1 196774795-196795406 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 242 liver: 313.3 adipose tissue: 1.2 -PLEKHM2 KIAA0842 ENSG00000116786 Pleckstrin homology domain containing, family M (with RUN domain) member 2 1 15684332-15734769 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032304 Approved Expressed in all cerebral cortex: 50.1 -CRYZ ENSG00000116791 Crystallin, zeta (quinone reductase) 1 74705482-74733408 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021921, HPA023290 Approved Supported Cytosol Expressed in all kidney: 342.7 -PHTF1 PHTF ENSG00000116793 Putative homeodomain transcription factor 1 1 113696831-113759489 Plasma proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA059486 Approved Nucleoli
Nuclear bodies Tissue enhanced 0 testis: 54.1 parathyroid gland: 18.8 -ZBTB17 MIZ1, pHZ-67, ZNF151, ZNF60 ENSG00000116809 Zinc finger and BTB domain containing 17 1 15941869-15976132 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005789 Approved Expressed in all testis: 21.9 -CD58 LFA3 ENSG00000116815 CD58 molecule 1 116514535-116571039 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all lung: 42.7 -TFAP2E AP2E ENSG00000116819 Transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) 1 35573370-35595328 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 7.2 lymph node: 2.1 -CD2 SRBC ENSG00000116824 CD2 molecule 1 116754385-116769228 CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002430, HPA003883 Supported Tissue enhanced 0 lymph node: 132.9 tonsil: 73.5 -TTF2 HuF2, ZGRF6 ENSG00000116830 Transcription termination factor, RNA polymerase II 1 117060303-117107453 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005776, HPA070762 Approved Supported Cytosol Mixed lymph node: 8.8 -NR5A2 B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1 ENSG00000116833 Nuclear receptor subfamily 5, group A, member 2 1 200027602-200177424 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA005455, HPA017067 Supported Uncertain Nuclear speckles Mixed small intestine: 19.8 -KIF21B DKFZP434J212, KIAA0449 ENSG00000116852 Kinesin family member 21B 1 200969390-201023700 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027249, HPA027274 Approved Tissue enhanced 0 cerebral cortex: 28.9 bone marrow: 22.9 -TMEM9 TMEM9A ENSG00000116857 Transmembrane protein 9 1 201134772-201171574 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 122.6 -ADPRHL2 ARH3, FLJ20446 ENSG00000116863 ADP-ribosylhydrolase like 2 1 36088875-36093932 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027104, HPA027141 Approved Validated Nucleoplasm Expressed in all fallopian tube: 40.7 -MAP7D1 FLJ10350, FLJ39022, PARCC1, RPRC1 ENSG00000116871 MAP7 domain containing 1 1 36155579-36180849 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028075 Approved Approved Microtubules
Cytosol Expressed in all cerebral cortex: 117.0 -WARS2 TrpRS ENSG00000116874 Tryptophanyl tRNA synthetase 2, mitochondrial 1 119031216-119140671 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069692 Supported Supported Plasma membrane
Mitochondria Expressed in all fallopian tube: 15.2 -HAO2 GIG16, HAOX2 ENSG00000116882 Hydroxyacid oxidase 2 (long chain) 1 119368779-119394130 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 266 kidney: 314.9;liver: 219.3 breast: 1.0 -OSCP1 C1orf102, NOR1 ENSG00000116885 Organic solute carrier partner 1 1 36415827-36450451 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028436, HPA052655 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Expressed in all testis: 126.0 -MRPS15 FLJ11564 ENSG00000116898 Mitochondrial ribosomal protein S15 1 36455718-36464437 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028100, HPA028134, HPA067137 Supported Supported Mitochondria Expressed in all testis: 241.1 -EXOC8 EXO84, Exo84p, SEC84 ENSG00000116903 Exocyst complex component 8 1 231332753-231337852 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027438 Approved Supported Cytosol Expressed in all parathyroid gland: 17.1 -GNPAT DAP-AT, DAPAT, DHAPAT ENSG00000116906 Glyceronephosphate O-acyltransferase 1 231241207-231277973 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 59.5 -TSNAX TRAX ENSG00000116918 Translin-associated factor X 1 231528653-231566524 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031054, HPA031055, CAB034263 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 53.4 -C1orf109 FLJ20508 ENSG00000116922 Chromosome 1 open reading frame 109 1 37681570-37692249 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027110, HPA027127 Supported Approved Nucleus
Cytosol Expressed in all parathyroid gland: 22.7 -RRAGC FLJ13311, GTR2 ENSG00000116954 Ras-related GTP binding C 1 38838198-38859823 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018247, HPA055489 Supported Supported Nucleus
Vesicles Expressed in all adipose tissue: 40.3 -TBCE HRD, KCS, KCS1, pac2 ENSG00000116957 Tubulin folding cofactor E 1 235367360-235448968 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026552, HPA026557 Uncertain Expressed in all thyroid gland: 19.1 -NID1 entactin, NID ENSG00000116962 Nidogen 1 1 235975830-236065162 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010044 Approved Expressed in all placenta: 323.7 -LGALS8 PCTA-1 ENSG00000116977 Lectin, galactoside-binding, soluble, 8 1 236518000-236552981 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012734, HPA030491 Approved Approved Plasma membrane Expressed in all testis: 101.8 -NT5C1A CN-I, CN-IA, CN1, CN1A, MGC119199, MGC119201 ENSG00000116981 5'-nucleotidase, cytosolic IA 1 39659121-39672038 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA050283, HPA054158 Supported Tissue enhanced 0 heart muscle: 8.1;skeletal muscle: 24.9 cerebral cortex: 4.8 -HPCAL4 DKFZp761G122, HLP4 ENSG00000116983 Hippocalcin like 4 1 39678648-39691689 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053808 Approved Cytosol Tissue enriched 11 cerebral cortex: 146.1 adrenal gland: 13.3 -MTR cblG ENSG00000116984 5-methyltetrahydrofolate-homocysteine methyltransferase 1 236795281-236903981 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044474 Supported Cytosol Expressed in all parathyroid gland: 28.4 -BMP8B BMP8, OP-2 ENSG00000116985 Bone morphogenetic protein 8b 1 39757182-39788861 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 thyroid gland: 35.7 adrenal gland: 8.0 -MYCL bHLHe38, LMYC, MYCL1 ENSG00000116990 V-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 1 39895426-39902256 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA063132 Supported Nucleus Tissue enhanced 0 skin: 41.7 urinary bladder: 24.6 -SIPA1L2 KIAA1389 ENSG00000116991 Signal-induced proliferation-associated 1 like 2 1 232397965-232561558 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024181, HPA027224 Approved Approved Nuclear membrane
Nuclear bodies
Golgi apparatus Mixed placenta: 28.9 -ZP4 ZPB ENSG00000116996 Zona pellucida glycoprotein 4 1 237877864-237890922 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA008547 Supported Not detected tonsil: 0.2 -RLF Zn-15L, ZNF292L ENSG00000117000 Rearranged L-myc fusion 1 40161373-40240921 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054653, HPA057300 Uncertain Approved Nucleus Expressed in all bone marrow: 20.8 -KMO ENSG00000117009 Kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 1 241532134-241595642 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031115, HPA056942 Supported Tissue enhanced 0 kidney: 31.3;liver: 46.5 spleen: 10.8 -ZNF684 MGC27466 ENSG00000117010 Zinc finger protein 684 1 40531561-40548169 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059153 Uncertain Approved Nucleus
Cytosol Mixed kidney: 6.8 -KCNQ4 DFNA2, Kv7.4 ENSG00000117013 Potassium channel, voltage gated KQT-like subfamily Q, member 4 1 40784012-40840452 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA018305 Uncertain Mixed smooth muscle: 2.5 -RIMS3 NIM3, RIM3 ENSG00000117016 Regulating synaptic membrane exocytosis 3 1 40620679-40665657 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055285 Approved Nucleoli
Mitochondria Tissue enriched 7 cerebral cortex: 60.6 adrenal gland: 8.3 -AKT3 PKBG, PRKBG, RAC-gamma ENSG00000117020 V-akt murine thymoma viral oncogene homolog 3 1 243488233-243851079 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013090, HPA026441 Approved Supported Cytosol Mixed cerebral cortex: 51.7 -ETV3 PE-1 ENSG00000117036 Ets variant 3 1 157121191-157138474 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004794 Supported Approved Nucleus Expressed in all parathyroid gland: 44.9 -ACADM ACAD1, MCAD, MCADH ENSG00000117054 Acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1 75724347-75787575 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006198, HPA026542 Supported Validated Mitochondria Expressed in all kidney: 325.2 -ST6GALNAC5 MGC3184, SIAT7E, ST6GalNAcV ENSG00000117069 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 1 76867441-77065711 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA065593, HPA070354 Uncertain Approved Vesicles Mixed lung: 8.8 -SLAMF1 CD150, SLAM ENSG00000117090 Signaling lymphocytic activation molecule family member 1 1 160608100-160647295 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002438 Approved Tissue enhanced 0 appendix: 15.9;lymph node: 21.3;tonsil: 14.8 spleen: 8.0 -CD48 BCM1, BLAST, hCD48, mCD48, SLAMF2 ENSG00000117091 CD48 molecule 1 160678746-160711851 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002497, HPA055146 Supported Supported Nucleoli fibrillar center
Plasma membrane
Cytosol Tissue enhanced 0 lymph node: 315.8;spleen: 216.7;tonsil: 235.9 appendix: 153.7 -ADGRL2 KIAA0786, LEC1, LPHH1, LPHN2 ENSG00000117114 Adhesion G protein-coupled receptor L2 1 81306160-81992436 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043447 Approved Plasma membrane
Cell Junctions Mixed thyroid gland: 72.8 -PADI2 KIAA0994, PDI2 ENSG00000117115 Peptidyl arginine deiminase, type II 1 17066761-17119435 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047735 Supported Tissue enhanced 0 cerebral cortex: 85.2;colon: 91.2;rectum: 101.6;skeletal muscle: 108.6 breast: 48.7 -SDHB SDH, SDH1 ENSG00000117118 Succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1 17018722-17054170 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002868, CAB009822, CAB068233, CAB068234, CAB068235 Supported Supported Nucleoplasm
Plasma membrane
Mitochondria Expressed in all kidney: 213.3 -MFAP2 MAGP, MAGP-1 ENSG00000117122 Microfibrillar-associated protein 2 1 16974502-16980835 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA007354 Supported Tissue enhanced 0 gallbladder: 101.1 endometrium: 82.2 -RPF1 BXDC5 ENSG00000117133 Ribosome production factor 1 homolog 1 84479259-84497790 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024642 Supported Validated Nucleoli Expressed in all testis: 58.5 -KDM5B CT31, JARID1B, PLU-1, PPP1R98, RBBP2H1A ENSG00000117139 Lysine (K)-specific demethylase 5B 1 202724491-202809470 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027179, HPA053723, CAB068193 Supported Supported Nucleus Tissue enriched 7 testis: 227.1 skin: 30.7 -UAP1 AgX, AGX1, SPAG2 ENSG00000117143 UDP-N-acetylglucosamine pyrophosphorylase 1 1 162561506-162599842 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014659 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 165.3 -ACTL8 CT57 ENSG00000117148 Actin-like 8 1 17755313-17827063 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027176 Approved Cytosol Tissue enriched 34 testis: 10.0 rectum: 0.2 -CTBS CTB ENSG00000117151 Chitobiase, di-N-acetyl- 1 84549606-84574480 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017043, HPA023594, HPA048810 Approved Uncertain Cytosol Mixed epididymis: 4.0 -RGS4 SCZD9 ENSG00000117152 Regulator of G-protein signaling 4 1 163068775-163076802 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030802 Approved Endoplasmic reticulum Tissue enriched 5 cerebral cortex: 289.9 adrenal gland: 54.3 -KLHL12 C3IP1 ENSG00000117153 Kelch-like family member 12 1 202891100-202928636 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071324 Supported Vesicles
Microtubule organizing center Expressed in all testis: 81.6 -IGSF21 MGC15730, RP11-121A23.1 ENSG00000117154 Immunoglobin superfamily, member 21 1 18107746-18378483 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044535 Approved Tissue enhanced 0 cerebral cortex: 29.0;spleen: 13.4 adrenal gland: 5.9 -SSX2IP ENSG00000117155 Synovial sarcoma, X breakpoint 2 interacting protein 1 84643707-84690803 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027306, HPA075946 Approved Approved Cell Junctions Tissue enhanced 0 testis: 191.0 cerebral cortex: 45.9 -ZNHIT6 BCD1, C1orf181, FLJ20729, NY-BR-75 ENSG00000117174 Zinc finger, HIT-type containing 6 1 85649423-85708433 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018132 Uncertain Approved Nuclear speckles
Vesicles Expressed in all cervix: 21.1 -PLA2G2D sPLA2S ENSG00000117215 Phospholipase A2, group IID 1 20111939-20119566 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 120.2;tonsil: 56.0 appendix: 21.3 -RBBP5 RBQ3, SWD1 ENSG00000117222 Retinoblastoma binding protein 5 1 205086142-205122015 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049042, HPA058085 Uncertain Validated Nucleus
Nucleoli Expressed in all thyroid gland: 16.3 -GBP3 FLJ10961 ENSG00000117226 Guanylate binding protein 3 1 89006666-89022894 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045657 Approved Mixed duodenum: 79.1 -GBP1 ENSG00000117228 Guanylate binding protein 1, interferon-inducible 1 89052319-89065360 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015450 Approved Expressed in all appendix: 122.1 -KIF17 KIAA1405, KIF17B, KIF3X, KLP-2, OSM-3 ENSG00000117245 Kinesin family member 17 1 20664014-20718017 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA032085 Uncertain Approved Nucleoplasm
Plasma membrane Tissue enriched 6 testis: 23.7 cerebral cortex: 3.8 -GPR89A UNQ192 ENSG00000117262 G protein-coupled receptor 89A 1 145607990-145670648 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA076096 Approved Endoplasmic reticulum Mixed kidney: 20.8 -CDK18 PCTAIRE3, PCTK3 ENSG00000117266 Cyclin-dependent kinase 18 1 205504595-205532793 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045429 Approved Approved Actin filaments Tissue enhanced 0 heart muscle: 65.7 cerebral cortex: 60.7 -RAB29 RAB7L, RAB7L1 ENSG00000117280 RAB29, member RAS oncogene family 1 205767986-205775460 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB020822, HPA026303 Approved Approved Nuclear membrane
Nucleoli Expressed in all kidney: 75.6 -CD160 BY55, NK1, NK28 ENSG00000117281 CD160 molecule 1 145719471-145739288 CD markers, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 spleen: 19.9 small intestine: 5.2 -ECE1 ECE ENSG00000117298 Endothelin converting enzyme 1 1 21217247-21345504 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001490, HPA013616 Approved Expressed in all parathyroid gland: 428.4 -HMGCL HL ENSG00000117305 3-hydroxymethyl-3-methylglutaryl-CoA lyase 1 23801885-23838620 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004727 Supported Expressed in all liver: 153.9 -GALE SDR1E1 ENSG00000117308 UDP-galactose-4-epimerase 1 23795599-23800804 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007340 Approved Approved Nucleus
Cytosol Expressed in all stomach: 113.6 -ID3 bHLHb25, HEIR-1 ENSG00000117318 Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1 23557918-23559794 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021353, HPA024677 Approved Supported Nucleoplasm Mixed seminal vesicle: 90.6 -CR2 CD21 ENSG00000117322 Complement component (3d/Epstein Barr virus) receptor 2 1 207454230-207489895 CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002659, HPA052942, HPA060715 Supported Group enriched 22 appendix: 70.8;lymph node: 207.6;spleen: 101.3;tonsil: 159.4 kidney: 6.1 -CD46 MCP, MGC26544, MIC10, TLX, TRA2.10 ENSG00000117335 CD46 molecule, complement regulatory protein 1 207752057-207795513 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010401, HPA016903 Supported Approved Plasma membrane Expressed in all parathyroid gland: 483.7 -PRPF3 hPrp3, Prp3, RP18, SNRNP90 ENSG00000117360 Pre-mRNA processing factor 3 1 150321476-150353195 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027226, HPA067116 Approved Validated Nucleoplasm Expressed in all endometrium: 40.4 -APH1A APH-1A, CGI-78 ENSG00000117362 APH1A gamma secretase subunit 1 150265399-150269580 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037272 Approved Expressed in all thyroid gland: 160.6 -P3H1 GROS1, LEPRE1, LEPRECAN, MGC117314 ENSG00000117385 Prolyl 3-hydroxylase 1 1 42746335-42767084 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012113, HPA016980 Approved Approved Nucleoli
Vesicles Tissue enhanced 0 placenta: 53.1 smooth muscle: 28.0 -SLC2A1 CSE, DYT18, DYT9, GLUT, GLUT1, HTLVR ENSG00000117394 Solute carrier family 2 (facilitated glucose transporter), member 1 1 42925375-42959173 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002759, HPA031345, HPA058494 Supported Supported Validated Plasma membrane Tissue enhanced 0 placenta: 133.9 skin: 31.3 -EBNA1BP2 EBP2, NOBP, P40 ENSG00000117395 EBNA1 binding protein 2 1 43164175-43270936 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026512, HPA028277 Approved Validated Nucleoli Expressed in all testis: 71.7 -CDC20 CDC20A, p55CDC ENSG00000117399 Cell division cycle 20 1 43358955-43363203 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004525, HPA045842, HPA055288 Supported Supported Nucleoplasm
Cytosol Tissue enhanced 0 testis: 63.8 tonsil: 46.9 -MPL CD110, TPOR ENSG00000117400 MPL proto-oncogene, thrombopoietin receptor 1 43337807-43352772 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007619 Uncertain Plasma membrane Tissue enhanced 0 testis: 1.8 ovary: 1.3 -ARTN ENOVIN, EVN, NBN ENSG00000117407 Artemin 1 43933320-43937241 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060012 Uncertain Mitochondria Tissue enhanced 0 parathyroid gland: 21.3 seminal vesicle: 12.0 -IPO13 IMP13, KIAA0724, RANBP13 ENSG00000117408 Importin 13 1 43946939-43968022 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB070425 Uncertain Expressed in all testis: 66.5 -ATP6V0B ATP6F, HATPL, VMA16 ENSG00000117410 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1 43974487-43978295 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044281 Approved Cytosol Expressed in all bone marrow: 181.8 -B4GALT2 beta4Gal-T2 ENSG00000117411 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 1 43978943-43991170 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007620, HPA047739 Supported Supported Golgi apparatus
Vesicles Expressed in all cerebral cortex: 49.6 -ERI3 FLJ22943, PINT1, PRNPIP ENSG00000117419 ERI1 exoribonuclease family member 3 1 44221070-44355260 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027147, HPA029895 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 81.3 -PTCH2 ENSG00000117425 Patched 2 1 44819844-44843063 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 parathyroid gland: 200.3 salivary gland: 32.3 -AKR1A1 ALR, DD3 ENSG00000117448 Aldo-keto reductase family 1, member A1 (aldehyde reductase) 1 45550543-45570049 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006246, HPA017919, HPA019649, HPA027734 Approved Supported Nucleoplasm
Cytosol Expressed in all kidney: 377.7 -PRDX1 NKEFA, PAGA ENSG00000117450 Peroxiredoxin 1 1 45511036-45523047 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004682, HPA007730 Approved Supported Mitochondria Expressed in all thyroid gland: 1203.6 -PIK3R3 p55 ENSG00000117461 Phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 1 46040140-46133036 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005751, HPA071988 Approved Approved Nucleoplasm
Vesicles Mixed testis: 46.2 -TSPAN1 NET-1, TSPAN-1 ENSG00000117472 Tetraspanin 1 1 46175073-46185958 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011909 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 colon: 534.2;rectum: 660.3 prostate: 315.2 -BLZF1 JEM-1 ENSG00000117475 Basic leucine zipper nuclear factor 1 1 169367970-169396540 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025703, HPA027331, HPA067113 Supported Supported Nucleus
Golgi apparatus Expressed in all testis: 58.0 -CCDC181 C1orf114, FLJ25846 ENSG00000117477 Coiled-coil domain containing 181 1 169394870-169460669 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA027189, HPA027275, HPA027281, HPA027312 Supported Approved Nuclear speckles Tissue enhanced 0 parathyroid gland: 22.7;testis: 49.4 fallopian tube: 19.6 -SLC19A2 THTR1, TRMA ENSG00000117479 Solute carrier family 19 (thiamine transporter), member 2 1 169463909-169486003 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006119, HPA016599 Uncertain Approved Cytosol Expressed in all gallbladder: 49.3 -FAAH FAAH-1 ENSG00000117480 Fatty acid amide hydrolase 1 46394265-46413848 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007425 Approved Uncertain Cytosol Expressed in all prostate: 56.6 -NSUN4 MGC22960, SHTAP ENSG00000117481 NOP2/Sun domain family, member 4 1 46340177-46365152 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027958, HPA028489 Approved Tissue enriched 14 testis: 99.1 adrenal gland: 7.2 -TMED5 CGI-100, p24g2, p24gamma2 ENSG00000117500 Transmembrane p24 trafficking protein 5 1 93149742-93180728 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050289 Approved Expressed in all kidney: 28.0 -MROH9 ARMC11, C1orf129, FLJ23550 ENSG00000117501 Maestro heat-like repeat family member 9 1 170935471-171064765 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028413 Uncertain Group enriched 7 fallopian tube: 3.9;lung: 1.2;testis: 2.7 endometrium: 0.3 -DR1 NC2-BETA, NC2B ENSG00000117505 Down-regulator of transcription 1 1 93345888-93369498 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050785, HPA055308 Supported Supported Nucleus Expressed in all testis: 101.8 -CNN3 ENSG00000117519 Calponin 3, acidic 1 94896949-94927278 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009849, HPA051237 Supported Validated Actin filaments
Cytosol Expressed in all placenta: 342.5 -PRRC2C BAT2D1, BAT2L2, KIAA1096, XTP2 ENSG00000117523 Proline-rich coiled-coil 2C 1 171485551-171593511 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025766, HPA028659 Approved Validated Cytosol Expressed in all parathyroid gland: 58.3 -F3 CD142 ENSG00000117525 Coagulation factor III (thromboplastin, tissue factor) 1 94529225-94541800 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009438, HPA049292, HPA069132 Approved Validated Vesicles Expressed in all placenta: 189.7 -ABCD3 PMP70, PXMP1, ZWS2 ENSG00000117528 ATP-binding cassette, sub-family D (ALD), member 3 1 94418455-94518666 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032026, HPA032027, CAB032516, CAB075749 Supported Validated Peroxisomes Expressed in all liver: 66.4 -VAMP4 ENSG00000117533 Vesicle-associated membrane protein 4 1 171700160-171742247 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050418 Supported Approved Golgi apparatus Expressed in all cerebral cortex: 22.4 -DPH5 CGI-30 ENSG00000117543 Diphthamide biosynthesis 5 1 100989623-101026088 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046439, HPA076234 Approved Uncertain Golgi apparatus Expressed in all ovary: 51.9 -FASLG APT1LG1, CD178, FasL, TNFSF6 ENSG00000117560 Fas ligand (TNF superfamily, member 6) 1 172659018-172666874 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA054959 Approved Tissue enhanced 0 lymph node: 5.9 spleen: 5.2 -PTBP2 brPTB, nPTB, PTB, PTBLP ENSG00000117569 Polypyrimidine tract binding protein 2 1 96721665-96823738 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047420 Uncertain Approved Nucleoplasm Mixed testis: 47.4 -TNFSF4 CD252, gp34, OX-40L, TXGP1 ENSG00000117586 Tumor necrosis factor (ligand) superfamily, member 4 1 173183734-173207313 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059579 Approved Approved Nucleus
Vesicles Tissue enhanced 0 testis: 7.5 appendix: 3.2 -PRDX6 1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX ENSG00000117592 Peroxiredoxin 6 1 173477266-173488807 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006983, CAB008663 Supported Supported Plasma membrane
Cytosol Expressed in all parathyroid gland: 363.4 -DARS2 FLJ10514 ENSG00000117593 Aspartyl-tRNA synthetase 2, mitochondrial 1 173824503-173858546 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026506, HPA026528 Supported Supported Nucleus
Mitochondria Expressed in all parathyroid gland: 24.9 -HSD11B1 HSD11, HSD11B, SDR26C1 ENSG00000117594 Hydroxysteroid (11-beta) dehydrogenase 1 1 209686178-209734950 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047729 Supported Group enriched 9 liver: 491.1;placenta: 104.6 ovary: 31.5 -IRF6 LPS, OFC6, VWS, VWS1 ENSG00000117595 Interferon regulatory factor 6 1 209785623-209806175 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063121, HPA076162 Approved Validated Nucleus
Cytosol Mixed skin: 84.2 -DIEXF C1orf107, DEF, MGC29875, UTP25 ENSG00000117597 Digestive organ expansion factor homolog (zebrafish) 1 209828007-209857565 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026640, HPA061682 Approved Approved Nucleoplasm
Golgi apparatus Mixed ovary: 8.8 -PLPPR5 LPPR5, PAP2, PAP2D, PRG5 ENSG00000117598 Phospholipid phosphatase related 5 1 98890245-99005032 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018072 Uncertain Approved Nucleus
Plasma membrane
Centrosome Group enriched 11 cerebral cortex: 12.0;testis: 4.0 adrenal gland: 0.7 -PLPPR4 KIAA0455, LPPR4, PHP1, PRG-1 ENSG00000117600 Phospholipid phosphatase related 4 1 99263953-99309590 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 10 cerebral cortex: 88.9 testis: 8.9 -SERPINC1 AT3, ATIII, MGC22579 ENSG00000117601 Serpin peptidase inhibitor, clade C (antithrombin), member 1 1 173903804-173917378 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001816, CAB016790, HPA024007 Supported Tissue enriched 675 liver: 2511.4 kidney: 3.7 -RCAN3 DSCR1L2 ENSG00000117602 RCAN family member 3 1 24502351-24541040 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034533, HPA064289 Approved Approved Nucleoli fibrillar center
Nuclear speckles Tissue enhanced 0 prostate: 52.6 lymph node: 23.2 -SYF2 CBPIN, DKFZp564O2082, fSAP29, NTC31, p29 ENSG00000117614 SYF2 pre-mRNA-splicing factor 1 25222679-25232502 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018265, HPA070710 Approved Supported Nuclear speckles Expressed in all ovary: 136.1 -RSRP1 C1orf63, DJ465N24.2.1 ENSG00000117616 Arginine/serine-rich protein 1 1 25242237-25338213 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058992, HPA067651 Uncertain Approved Nucleoplasm Expressed in all adrenal gland: 34.5 -SLC35A3 ENSG00000117620 Solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 1 99969789-100026979 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015253 Uncertain Expressed in all rectum: 47.2 -RCOR3 FLJ10876 ENSG00000117625 REST corepressor 3 1 211258377-211316385 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007413 Supported Approved Nucleus
Nucleoli Expressed in all testis: 67.1 -STMN1 C1orf215, FLJ32206, Lag, LAP18, OP18, PP17, PP19, PR22, SMN ENSG00000117632 Stathmin 1 1 25884181-25906991 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010107 Approved Supported Cytosol Expressed in all cerebral cortex: 1042.5 -MTFR1L FAM54B ENSG00000117640 Mitochondrial fission regulator 1-like 1 25818640-25832942 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027124, HPA027130 Approved Approved Cell Junctions
Mitochondria Expressed in all parathyroid gland: 155.3 -MAN1C1 HMIC ENSG00000117643 Mannosidase, alpha, class 1C, member 1 1 25617468-25786207 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048352 Uncertain Uncertain Nucleus
Vesicles Mixed thyroid gland: 40.6 -NEK2 NEK2A, NLK1, PPP1R111, RP67 ENSG00000117650 NIMA-related kinase 2 1 211658657-211675630 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017530, HPA064967 Uncertain Supported Nucleus
Centrosome Tissue enriched 11 testis: 120.5 bone marrow: 11.3 -RPS6KA1 HU-1, p90Rsk, RSK, RSK1 ENSG00000117676 Ribosomal protein S6 kinase, 90kDa, polypeptide 1 1 26529761-26575030 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003852, HPA007981 Approved Supported Nucleus
Cytosol Mixed small intestine: 39.7 -DHDDS DS, FLJ13102, HDS, RP59 ENSG00000117682 Dehydrodolichyl diphosphate synthase subunit 1 26432282-26471294 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026721, HPA026727 Uncertain Uncertain Plasma membrane Expressed in all adipose tissue: 54.6 -NENF CIR2, SCIRP10, SPUF ENSG00000117691 Neudesin neurotrophic factor 1 212432887-212446379 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026763, HPA028488 Uncertain Validated Nucleus Expressed in all cervix: 82.4 -NSL1 C1orf48, DC8, DKFZP566O1646, MIS14 ENSG00000117697 NSL1, MIS12 kinetochore complex component 1 212726153-212791782 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045761, HPA053721 Supported Supported Nucleoplasm
Nuclear speckles
Cytosol Expressed in all cerebral cortex: 35.7 -PROX1 ENSG00000117707 Prospero homeobox 1 1 213983181-214041502 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000842, HPA001030 Supported Nucleoplasm Tissue enhanced 0 liver: 45.5 adrenal gland: 13.4 -ARID1A B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1 ENSG00000117713 AT rich interactive domain 1A (SWI-like) 1 26696033-26782104 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005456, CAB016334 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 40.4 -CENPF hcp-1 ENSG00000117724 Centromere protein F, 350/400kDa 1 214603195-214664588 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009581, HPA052382 Approved Supported Nucleoplasm Tissue enhanced 0 bone marrow: 17.7;testis: 18.7 lymph node: 10.2 -RPA2 ENSG00000117748 Replication protein A2, 32kDa 1 27891524-27914746 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016538, HPA026306, HPA026309 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all testis: 103.3 -PPP1R8 ard-1, ARD1, NIPP-1, NIPP1, PRO2047 ENSG00000117751 Protein phosphatase 1, regulatory subunit 8 1 27830778-27851676 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027406, HPA027417, HPA027452 Supported Validated Nucleoplasm
Nuclear speckles Expressed in all endometrium: 46.5 -STX12 STX13, STX14 ENSG00000117758 Syntaxin 12 1 27773183-27824452 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041038, HPA055300 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Expressed in all thyroid gland: 155.4 -MARC2 FLJ20605, MOSC2 ENSG00000117791 Mitochondrial amidoxime reducing component 2 1 220748225-220784815 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015085, HPA017572 Supported Tissue enhanced 0 parathyroid gland: 332.7 kidney: 138.5 -SLC5A9 SGLT4 ENSG00000117834 Solute carrier family 5 (sodium/sugar cotransporter), member 9 1 48222685-48248644 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050263 Approved Actin filaments
Cytosol Group enriched 10 duodenum: 43.8;small intestine: 46.4 lung: 4.5 -OSBPL9 ENSG00000117859 Oxysterol binding protein-like 9 1 51577179-51798427 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027378, HPA027397 Supported Supported Golgi apparatus
Vesicles Expressed in all parathyroid gland: 96.5 -TXNDC12 AGR1, ERP18, ERP19, hAG-1, PDIA16, TLP19 ENSG00000117862 Thioredoxin domain containing 12 (endoplasmic reticulum) 1 52020131-52056171 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all fallopian tube: 49.3 -ESYT2 CHR2SYT, FAM62B, KIAA1228 ENSG00000117868 Extended synaptotagmin-like protein 2 7 158730995-158830253 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002132 Approved Uncertain Cytosol Expressed in all thyroid gland: 79.8 -CD3EAP ASE-1, CAST, PAF49 ENSG00000117877 CD3e molecule, epsilon associated protein 19 45406209-45410766 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041664, HPA041734 Supported Validated Nucleus
Nucleoli fibrillar center
Mitochondria Mixed appendix: 5.6 -MESDC2 BOCA, KIAA0081, MESD ENSG00000117899 Mesoderm development candidate 2 15 80946289-80989878 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039414, HPA041721 Approved Supported Nuclear bodies
Endoplasmic reticulum
Cytosol Expressed in all thyroid gland: 55.6 -RCN2 E6BP, ERC-55, ERC55, TCBP49 ENSG00000117906 Reticulocalbin 2, EF-hand calcium binding domain 15 76931619-76954392 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030694, HPA030695 Supported Supported Validated Endoplasmic reticulum Expressed in all epididymis: 384.9 -CHRNB4 ENSG00000117971 Cholinergic receptor, nicotinic, beta 4 (neuronal) 15 78624119-78727754 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adrenal gland: 3.2;testis: 5.3 appendix: 0.9 -MUC5B MG1, MUC5 ENSG00000117983 Mucin 5B, oligomeric mucus/gel-forming 11 1223066-1262172 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008246, CAB009396 Supported Validated Vesicles Group enriched 11 cervix, uterine: 347.7;gallbladder: 346.8 colon: 32.6 -CTSD CLN10, CPSD ENSG00000117984 Cathepsin D 11 1752752-1763992 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000109, HPA003001 Supported Expressed in all lung: 1071.1 -COLEC11 CL-K1, MGC3279 ENSG00000118004 Collectin sub-family member 11 2 3594832-3644644 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035241 Approved Tissue enhanced 0 gallbladder: 102.4 adrenal gland: 36.3 -STAG1 SA-1, SA1, SCC3A ENSG00000118007 Stromal antigen 1 3 136336233-136752403 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035015, HPA058653 Supported Validated Nucleus
Nuclear bodies Expressed in all endometrium: 31.7 -A4GNT alpha4GnT ENSG00000118017 Alpha-1,4-N-acetylglucosaminyltransferase 3 138123718-138132387 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA008017 Supported Tissue enriched 8 stomach: 24.6 gallbladder: 3.2 -STK11 LKB1, PJS ENSG00000118046 Serine/threonine kinase 11 19 1177558-1228435 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016231, HPA017254, CAB022105, HPA067481 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 70.3 -KMT2A ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1 ENSG00000118058 Lysine (K)-specific methyltransferase 2A 11 118436490-118526832 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017794, CAB024270, HPA044910 Supported Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 31.1 -TREH MGC129621, TRE, TREA ENSG00000118094 Trehalase (brush-border membrane glycoprotein) 11 118657316-118679690 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039913, HPA042045 Supported Tissue enhanced 0 duodenum: 62.3;small intestine: 74.1 kidney: 14.7 -IFT46 C11orf2, C11orf60, CFAP32, FLJ21827 ENSG00000118096 Intraflagellar transport 46 11 118544528-118572970 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037909, HPA057550 Approved Approved Actin filaments Expressed in all fallopian tube: 96.4 -MMP8 CLG1 ENSG00000118113 Matrix metallopeptidase 8 11 102711795-102727050 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021221, HPA022935 Supported Tissue enriched 103 bone marrow: 336.3 endometrium: 3.2 -APOA1 ENSG00000118137 Apolipoprotein A-I 11 116835751-116837950 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016778, HPA046715 Supported Approved Vesicles
Cytosol Tissue enhanced 0 liver: 8446.1;small intestine: 4222.2 duodenum: 1654.8 -ZNF541 DKFZp434I1930 ENSG00000118156 Zinc finger protein 541 19 47520685-47555856 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058541 Approved Nucleoplasm
Cytosol Tissue enriched 11 testis: 19.2 ovary: 1.7 -SLC8A2 KIAA1087, NCX2 ENSG00000118160 Solute carrier family 8 (sodium/calcium exchanger), member 2 19 47428017-47472168 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA050818, HPA054671 Supported Tissue enriched 11 cerebral cortex: 68.4 endometrium: 6.2 -KPTN 2E4 ENSG00000118162 Kaptin (actin binding protein) 19 47475144-47484268 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041710, HPA041796 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Mixed cerebral cortex: 7.9 -RPS25 S25 ENSG00000118181 Ribosomal protein S25 11 119015712-119018691 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031801 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all ovary: 944.6 -KIF14 KIAA0042 ENSG00000118193 Kinesin family member 14 1 200551497-200620734 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038061, HPA058220 Uncertain Supported Cytosol Mixed testis: 4.6 -TNNT2 CMD1D, CMH2, CMPD2 ENSG00000118194 Troponin T type 2 (cardiac) 1 201359008-201377762 Candidate cardiovascular disease genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015371, HPA015774, HPA017888 Supported Uncertain Nucleus
Nucleoli
Focal adhesion sites Tissue enriched 199 heart muscle: 5036.0 skin: 25.2 -DDX59 DKFZP564B1023, ZNHIT5 ENSG00000118197 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 1 200623896-200669969 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047166 Approved Approved Nucleus
Actin filaments Expressed in all breast: 33.2 -CAMSAP2 CAMSAP1L1, KIAA1078 ENSG00000118200 Calmodulin regulated spectrin-associated protein family, member 2 1 200739558-200860704 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026304, HPA026511, HPA027302 Supported Supported Microtubule ends
Cytosol Mixed cerebral cortex: 64.7 -ATF6 ATF6A ENSG00000118217 Activating transcription factor 6 1 161766294-161964070 Plasma proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005935 Approved Approved Cytosol Expressed in all parathyroid gland: 40.6 -CRYGD CRYG4 ENSG00000118231 Crystallin, gamma D 2 208121607-208124501 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 13 ovary: 21.5 bone marrow: 1.6 -MREG DSU, FLJ10116, WDT2 ENSG00000118242 Melanoregulin 2 215942805-216034096 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA068583 Approved Vesicles Mixed esophagus: 29.5 -TNP1 ENSG00000118245 Transition protein 1 (during histone to protamine replacement) 2 216859458-216860064 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044387 Supported Tissue enriched 2182 testis: 4375.5 thyroid gland: 2.0 -FASTKD2 KIAA0971 ENSG00000118246 FAST kinase domains 2 2 206765357-206792509 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067191 Supported Mitochondria Expressed in all thyroid gland: 30.0 -NRP2 VEGF165R2 ENSG00000118257 Neuropilin 2 2 205681990-205798133 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039980, HPA054974 Approved Supported Vesicles
Plasma membrane Mixed smooth muscle: 83.5 -CREB1 ENSG00000118260 CAMP responsive element binding protein 1 2 207529737-207603431 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003803, HPA019150 Supported Validated Nucleoplasm Expressed in all testis: 58.7 -KLF7 UKLF ENSG00000118263 Kruppel-like factor 7 (ubiquitous) 2 207074137-207167267 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030490 Approved Approved Golgi apparatus Expressed in all smooth muscle: 30.6 -TTR CTS, CTS1, HsT2651, PALB ENSG00000118271 Transthyretin 18 31591726-31599021 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002517, HPA002550, CAB062567, CAB073406 Supported Approved Golgi apparatus Tissue enriched 27 liver: 6311.4 pancreas: 235.0 -B4GALT6 beta4GalT-VI ENSG00000118276 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 18 31622247-31685836 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB020701, HPA058284 Approved Mixed cerebral cortex: 21.6 -C1orf54 FLJ23221 ENSG00000118292 Chromosome 1 open reading frame 54 1 150268200-150280916 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026518 Approved Approved Vesicles Expressed in all spleen: 77.4 -CA14 ENSG00000118298 Carbonic anhydrase XIV 1 150257159-150265078 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008482 Approved Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 10.6;seminal vesicle: 21.1 skeletal muscle: 9.4 -CASC1 FLJ10921, LAS1, PPP1R54 ENSG00000118307 Cancer susceptibility candidate 1 12 25108420-25195162 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039662 Supported Tissue enhanced 0 fallopian tube: 22.4;testis: 41.6 parathyroid gland: 7.5 -LRMP JAW1 ENSG00000118308 Lymphoid-restricted membrane protein 12 25021002-25108334 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002967, HPA018505 Supported Supported Nucleus
Vesicles
Cytosol Tissue enhanced 0 lymph node: 210.1;tonsil: 193.0 appendix: 65.5 -ATP10B ATPVB, FLJ21477, KIAA0715 ENSG00000118322 ATPase, class V, type 10B 5 160563120-160852214 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA034574 Uncertain Tissue enhanced 0 colon: 36.7;rectum: 40.8 gallbladder: 21.5 -SPCS2 KIAA0102 ENSG00000118363 Signal peptidase complex subunit 2 11 74949247-74979031 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013386 Approved Approved Nucleus Expressed in all epididymis: 264.2 -USP35 KIAA1372 ENSG00000118369 Ubiquitin specific peptidase 35 11 78188812-78214711 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055213, HPA058592 Uncertain Approved Nucleus
Nucleoli fibrillar center Tissue enhanced 0 parathyroid gland: 33.6 adrenal gland: 14.9 -ELOVL4 CT118, SCA34, STGD2, STGD3 ENSG00000118402 ELOVL fatty acid elongase 4 6 79914812-79947580 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 24.1;skin: 50.8 parathyroid gland: 15.5 -FILIP1 FILIP, KIAA1275 ENSG00000118407 Filamin A interacting protein 1 6 75291859-75493738 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053564 Approved Uncertain Plasma membrane
Actin filaments Tissue enhanced 0 heart muscle: 34.9 smooth muscle: 19.4 -CASP8AP2 CED-4, FLASH, FLJ11208, KIAA1315, RIP25 ENSG00000118412 Caspase 8 associated protein 2 6 89829894-89874436 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053573 Approved Nucleoli
Nuclear bodies Mixed lymph node: 6.5 -HMGN3 TRIP7 ENSG00000118418 High mobility group nucleosomal binding domain 3 6 79201245-79234738 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018370, HPA027971 Supported Validated Nucleus
Cytosol Expressed in all fallopian tube: 332.5 -UBE3D C6orf157, DKFZp434A1520, H10BH, UBE2CBP, YJR141W ENSG00000118420 Ubiquitin protein ligase E3D 6 82892398-83065841 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027231 Uncertain Approved Rods & Rings Mixed fallopian tube: 6.2 -CNR1 CANN6, CB-R, CB1, CB1A, CB1K5, CNR ENSG00000118432 Cannabinoid receptor 1 (brain) 6 88139864-88166359 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005603, HPA042256 Approved Approved Plasma membrane
Actin filaments Tissue enhanced 0 cerebral cortex: 32.2 adipose tissue: 12.1 -SPACA1 SAMP32 ENSG00000118434 Sperm acrosome associated 1 6 88047789-88066832 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026744, HPA043297 Supported Tissue enriched 422 testis: 51.0 kidney: 0.1 -ANKRD13C dJ677H15.3, DKFZP566D1346 ENSG00000118454 Ankyrin repeat domain 13C 1 70260588-70354734 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026766 Uncertain Expressed in all parathyroid gland: 18.8 -SGIP1 DKFZp761D221 ENSG00000118473 SH3-domain GRB2-like (endophilin) interacting protein 1 1 66533383-66748299 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017963 Approved Approved Mitochondria Tissue enhanced 0 cerebral cortex: 36.3 endometrium: 16.9 -PHF3 ENSG00000118482 PHD finger protein 3 6 63635820-63779336 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024676, HPA025763 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 47.8 -ZC2HC1B C6orf94, dJ468K18.5, FAM164B ENSG00000118491 Zinc finger, C2HC-type containing 1B 6 143864436-143938356 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 74 testis: 23.2 skin: 0.3 -ADGB C6orf103, CAPN16, dJ408K24.1, FLJ23121 ENSG00000118492 Androglobin 6 146598965-146815462 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036340, HPA036341 Supported Uncertain Nucleoplasm
Mitochondria Group enriched 24 fallopian tube: 14.6;testis: 58.0 lung: 1.4 -PLAGL1 LOT1, ZAC ENSG00000118495 Pleiomorphic adenoma gene-like 1 6 143940300-144064599 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA055706 Supported Nuclear bodies
Golgi apparatus
Vesicles Expressed in all placenta: 362.2 -FBXO30 Fbx30, MGC21674 ENSG00000118496 F-box protein 30 6 145793502-145814753 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012583 Approved Microtubules Mixed thyroid gland: 13.5 -TNFAIP3 A20, OTUD7C ENSG00000118503 Tumor necrosis factor, alpha-induced protein 3 6 137867188-137883312 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002116 Approved Approved Centrosome
Cytosol Expressed in all bone marrow: 345.8 -AKAP7 AKAP15, AKAP18 ENSG00000118507 A kinase (PRKA) anchor protein 7 6 131135666-131283535 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027172, HPA028327 Supported Expressed in all adrenal gland: 72.9 -RAB32 ENSG00000118508 RAB32, member RAS oncogene family 6 146543693-146554965 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025731 Approved Approved Cytosol Expressed in all bone marrow: 92.1 -MYB c-myb ENSG00000118513 V-myb avian myeloblastosis viral oncogene homolog 6 135181315-135219173 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017704 Approved Approved Nucleus
Plasma membrane Tissue enhanced 0 breast: 25.9;rectum: 29.6 colon: 25.7 -ALDH8A1 ALDH12 ENSG00000118514 Aldehyde dehydrogenase 8 family, member A1 6 134917390-134950122 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026292, HPA055414 Supported Approved Centrosome Group enriched 24 kidney: 73.9;liver: 127.6 epididymis: 4.2 -SGK1 SGK ENSG00000118515 Serum/glucocorticoid regulated kinase 1 6 134169246-134318112 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022085, CAB025148, HPA051251 Approved Supported Nuclear speckles
Cytosol Expressed in all parathyroid gland: 778.6 -RNF146 dactylidin, dJ351K20.1, DKFZp434O1427 ENSG00000118518 Ring finger protein 146 6 127266610-127288567 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027158, HPA027209 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all endometrium: 94.0 -ARG1 ENSG00000118520 Arginase 1 6 131573144-131584332 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003595, CAB009434, HPA024006, CAB056159 Supported Tissue enhanced 0 bone marrow: 171.2;liver: 564.5 skin: 78.2 -CTGF CCN2, IGFBP8 ENSG00000118523 Connective tissue growth factor 6 131948176-131951373 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005123, HPA031074, HPA031075 Approved Validated Golgi apparatus
Vesicles Expressed in all cervix: 841.0 -TCF21 bHLHa23, POD1 ENSG00000118526 Transcription factor 21 6 133889138-133895553 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA013189 Uncertain Tissue enhanced 0 placenta: 62.1;spleen: 47.8 ovary: 32.1 -PMFBP1 ENSG00000118557 Polyamine modulated factor 1 binding protein 1 16 72112157-72176878 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008518, HPA056716 Uncertain Approved Endoplasmic reticulum Tissue enhanced 0 epididymis: 17.7;testis: 32.3 parathyroid gland: 7.2 -FBXL5 FBL4, FBL5, FLR1 ENSG00000118564 F-box and leucine-rich repeat protein 5 4 15604539-15681679 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all kidney: 133.4 -MED28 DKFZP434N185, EG1, magicin ENSG00000118579 Mediator complex subunit 28 4 17614631-17634105 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035900, HPA035901 Uncertain Supported Nucleoplasm Expressed in all lymph node: 47.4 -SLC16A7 MCT2 ENSG00000118596 Solute carrier family 16 (monocarboxylate transporter), member 7 12 59596067-59789855 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005911 Approved Approved Nucleoplasm
Plasma membrane Mixed adipose tissue: 24.8 -TMEM5 HP10481 ENSG00000118600 Transmembrane protein 5 12 63779803-63809558 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA064014 Approved Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 23.1 -ZNF430 FLJ13659 ENSG00000118620 Zinc finger protein 430 19 21020620-21060050 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA059135 Uncertain Mixed ovary: 15.8 -VAMP8 EDB ENSG00000118640 Vesicle-associated membrane protein 8 2 85561562-85582031 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006882, CAB037132, CAB037147 Supported Expressed in all lung: 328.4 -DCLRE1B FLJ12810, FLJ13998, SNM1B ENSG00000118655 DNA cross-link repair 1B 1 113905141-113914086 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064934 Supported Nucleoplasm
Nuclear bodies Mixed spleen: 5.5 -MYL12B MRLC2 ENSG00000118680 Myosin, light chain 12B, regulatory 18 3261909-3278284 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039262, HPA045244, HPA059197 Supported Approved Nucleus
Nucleoli fibrillar center Expressed in all epididymis: 577.0 -FOXO3 AF6q21, FKHRL1, FOXO2, FOXO3A ENSG00000118689 Forkhead box O3 6 108559835-108684774 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004074, HPA063104 Supported Validated Nucleus Expressed in all ovary: 54.9 -ARMC2 bA787I22.1, DKFZp434P0714 ENSG00000118690 Armadillo repeat containing 2 6 108848416-108974472 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA025809, HPA053696 Uncertain Approved Nucleus Tissue enhanced 0 testis: 61.6 fallopian tube: 33.3 -GHRH GHRF ENSG00000118702 Growth hormone releasing hormone 20 37251082-37261835 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 duodenum: 3.5;heart muscle: 1.8 adrenal gland: 1.4 -RPN2 RIBIIR, RPN-II, RPNII, SWP1 ENSG00000118705 Ribophorin II 20 37178410-37241623 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008297, CAB019277, HPA025922 Supported Supported Endoplasmic reticulum Expressed in all epididymis: 358.1 -TGIF2 ENSG00000118707 TGFB-induced factor homeobox 2 20 36573488-36593950 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA053786 Supported Nucleoplasm Mixed fallopian tube: 37.9 -CASQ2 PDIB2 ENSG00000118729 Calsequestrin 2 (cardiac muscle) 1 115700007-115768781 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027285, HPA055298 Supported Tissue enriched 11 heart muscle: 672.9 skeletal muscle: 62.4 -OLFM3 NOE3 ENSG00000118733 Olfactomedin 3 1 101802574-101997030 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050297 Uncertain Vesicles Tissue enriched 15 cerebral cortex: 26.8 adrenal gland: 1.8 -PKD2 Pc-2, PC2, PKD4, TRPP2 ENSG00000118762 Polycystic kidney disease 2 (autosomal dominant) 4 88007668-88077777 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004544, HPA015794 Approved Validated Endoplasmic reticulum Expressed in all endometrium: 100.4 -ABCG2 ABCP, BCRP, CD338, EST157481, MXR ENSG00000118777 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 4 88090264-88231322 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037299, HPA054719 Supported Validated Nucleus
Plasma membrane Tissue enhanced 0 small intestine: 116.1 seminal vesicle: 55.4 -SPP1 BNSP, BSPI, ETA-1, OPN ENSG00000118785 Secreted phosphoprotein 1 4 87975650-87983426 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002212, HPA027540, HPA027541 Approved Supported Golgi apparatus Tissue enhanced 0 gallbladder: 4002.0;kidney: 2385.1;placenta: 4016.3 cerebral cortex: 797.1 -STBD1 FLJ41801, GENX-3414 ENSG00000118804 Starch binding domain 1 4 76306026-76311599 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011952, HPA012849 Supported Supported Cytosol Tissue enhanced 0 adipose tissue: 46.9 skeletal muscle: 32.8 -CCNI CCNI1 ENSG00000118816 Cyclin I 4 77047158-77076005 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB010206, HPA039853, HPA061470 Uncertain Supported Nucleoplasm
Nuclear bodies
Golgi apparatus Expressed in all thyroid gland: 451.7 -RARRES1 LXNL, TIG1 ENSG00000118849 Retinoic acid receptor responder (tazarotene induced) 1 3 158696892-158732696 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003892 Uncertain Approved Endoplasmic reticulum
Golgi apparatus Mixed appendix: 80.1 -MFSD1 FLJ14153, UG0581B09 ENSG00000118855 Major facilitator superfamily domain containing 1 3 158732198-158829719 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057924, HPA065858 Approved Approved Nucleus
Nucleoli Expressed in all spleen: 35.8 -RAB3GAP2 DKFZP434D245, KIAA0839, RAB3-GAP150, SPG69 ENSG00000118873 RAB3 GTPase activating protein subunit 2 (non-catalytic) 1 220148293-220272454 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026273, HPA027299 Approved Supported Plasma membrane
Cytosol Expressed in all parathyroid gland: 34.7 -EEF2KMT FAM86A, MGC19636, SB153 ENSG00000118894 Eukaryotic elongation factor 2 lysine methyltransferase 16 5084304-5097808 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041610 Approved Uncertain Vesicles Mixed parathyroid gland: 11.8 -PPL ENSG00000118898 Periplakin 16 4882507-4960741 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042550, HPA059859 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Group enriched 7 esophagus: 560.8;skin: 149.9 tonsil: 54.0 -UBN1 ENSG00000118900 Ubinuclein 1 16 4846665-4882360 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061029, HPA069045 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 70.3 -KLF12 AP-2rep, AP2REP, HSPC122 ENSG00000118922 Kruppel-like factor 12 13 73686089-74133905 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064146 Approved Nucleoplasm
Cytosol Mixed lymph node: 17.8 -UCHL3 ENSG00000118939 Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 13 75549480-75606020 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019678, CAB037139, CAB037208 Approved Supported Nucleus
Cytosol Expressed in all testis: 90.1 -PCDH17 PCDH68, PCH68 ENSG00000118946 Protocadherin 17 13 57631810-57729311 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026817 Uncertain Approved Vesicles
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 25.8;spleen: 34.3 lung: 18.3 -HS1BP3 FLJ14249, HS1-BP3 ENSG00000118960 HCLS1 binding protein 3 2 20560448-20651089 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035050 Approved Approved Nucleoli
Cytosol Expressed in all adrenal gland: 33.4 -LDAH C2orf43, FLJ21820 ENSG00000118961 Lipid droplet associated hydrolase 2 20684014-20823130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034729, HPA034730 Approved Uncertain Nuclear speckles
Cytosol Mixed parathyroid gland: 20.2 -WDR35 IFT121, IFTA1, KIAA1336, MGC33196 ENSG00000118965 WD repeat domain 35 2 19910260-19990131 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044147 Approved Mixed parathyroid gland: 25.7 -CCND2 ENSG00000118971 Cyclin D2 12 4273772-4305350 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049138, HPA054196 Approved Supported Nucleoplasm Mixed epididymis: 55.1 -FGF23 ENSG00000118972 Fibroblast growth factor 23 12 4368227-4379728 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed epididymis: 2.0 -ELL2 ENSG00000118985 Elongation factor, RNA polymerase II, 2 5 95885098-95962071 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013569 Supported Nucleoplasm Expressed in all skin: 69.0 -DNAH7 KIAA0944 ENSG00000118997 Dynein, axonemal, heavy chain 7 2 195737703-196068812 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034724, HPA044070 Approved Supported Cytosol Tissue enhanced 0 fallopian tube: 15.4;testis: 18.0 thyroid gland: 4.6 -CYP20A1 CYP-M ENSG00000119004 Cytochrome P450, family 20, subfamily A, polypeptide 1 2 203238449-203305840 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055872, HPA058461 Uncertain Approved Plasma membrane
Cell Junctions
Actin filaments Mixed thyroid gland: 18.7 -NDUFB3 B12 ENSG00000119013 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 2 201071433-201085750 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034596 Approved Expressed in all skeletal muscle: 180.0 -GTF3C3 TFIIIC102, TFiiiC2-102 ENSG00000119041 General transcription factor IIIC, polypeptide 3, 102kDa 2 196763032-196799725 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069179 Supported Nucleus
Nuclear membrane Expressed in all parathyroid gland: 40.1 -SATB2 FLJ21474, KIAA1034 ENSG00000119042 SATB homeobox 2 2 199269500-199471266 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001042, CAB023669, HPA029543, CAB062562, CAB067751, CAB068229, CAB068230, CAB068231 Supported Supported Nucleoplasm Group enriched 6 cerebral cortex: 22.8;colon: 37.7;rectum: 48.3 small intestine: 6.5 -UBE2B HHR6B, RAD6B, UBC2 ENSG00000119048 Ubiquitin-conjugating enzyme E2B 5 134371179-134391992 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003875, HPA051765, HPA065898 Supported Nucleoplasm
Vesicles
Plasma membrane
Cytosol Expressed in all adrenal gland: 99.5 -TRPM6 CHAK2, FLJ22628, HOMG, HSH ENSG00000119121 Transient receptor potential cation channel, subfamily M, member 6 9 74722495-74888094 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 colon: 13.3;rectum: 18.5 small intestine: 8.9 -GDA ENSG00000119125 Guanine deaminase 9 72114595-72257193 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019352, HPA024099, HPA030387 Supported Approved Nucleus Tissue enhanced 0 cerebral cortex: 102.6;duodenum: 97.8;small intestine: 106.3 kidney: 43.2 -KLF9 BTEB1 ENSG00000119138 Kruppel-like factor 9 9 70384597-70414624 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA029308 Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all smooth muscle: 88.0 -TJP2 DFNA51, X104, ZO-2, ZO2 ENSG00000119139 Tight junction protein 2 9 69121264-69255208 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001813, CAB009228 Supported Validated Plasma membrane
Cell Junctions
Cytosol Expressed in all parathyroid gland: 136.2 -C2orf40 augurin, ECRG4 ENSG00000119147 Chromosome 2 open reading frame 40 2 106063246-106078159 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008546 Uncertain Tissue enhanced 0 seminal vesicle: 115.1;thyroid gland: 127.1 prostate: 57.6 -ITGB1BP1 ICAP-1A, ICAP-1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B ENSG00000119185 Integrin beta 1 binding protein 1 2 9403475-9423547 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071538 Supported Nucleoplasm
Cytosol Expressed in all adipose tissue: 124.9 -CPSF3 CPSF-73, CPSF73, YSH1 ENSG00000119203 Cleavage and polyadenylation specific factor 3, 73kDa 2 9423568-9473101 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034657 Uncertain Expressed in all testis: 87.1 -PIGZ FLJ12768, MGC52163, SMP3 ENSG00000119227 Phosphatidylinositol glycan anchor biosynthesis, class Z 3 196946343-196969060 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058599, HPA059920 Approved Uncertain Vesicles Tissue enhanced 0 colon: 18.8;rectum: 18.4 cerebral cortex: 10.9 -SENP5 MGC27076 ENSG00000119231 SUMO1/sentrin specific peptidase 5 3 196867856-196934714 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 37.5 -CCDC92 FLJ22471 ENSG00000119242 Coiled-coil domain containing 92 12 123918660-123972831 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038560, HPA057580 Approved Supported Nucleoplasm
Centrosome Mixed testis: 18.0 -C1orf198 DKFZp667D152, FLJ14525, FLJ16283, FLJ38847, MGC10710 ENSG00000119280 Chromosome 1 open reading frame 198 1 230837119-230869589 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004798 Approved Supported Cytosol Expressed in all lung: 99.3 -TRIM67 TNL ENSG00000119283 Tripartite motif containing 67 1 231162112-231221556 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA034776 Uncertain Tissue enriched 28 cerebral cortex: 10.3 testis: 0.3 -HEATR1 BAP28, FLJ10359, UTP10 ENSG00000119285 HEAT repeat containing 1 1 236549005-236604504 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046917, HPA062200 Approved Validated Nucleoli fibrillar center
Mitochondria Expressed in all testis: 26.9 -PTBP3 DKFZp781I1117, ROD1 ENSG00000119314 Polypyrimidine tract binding protein 3 9 112217716-112333667 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048374 Approved Nucleus Expressed in all testis: 43.9 -RAD23B HHR23B, HR23B, P58 ENSG00000119318 RAD23 homolog B, nucleotide excision repair protein 9 107283137-107332194 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029718, HPA029720, CAB033868 Supported Supported Nucleoplasm
Cytosol Expressed in all placenta: 110.0 -FKBP15 FKBP133, KIAA0674, PPP1R76, WAFL ENSG00000119321 FK506 binding protein 15, 133kDa 9 113161006-113221361 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007979 Approved Approved Nucleoli
Cytosol Expressed in all parathyroid gland: 48.5 -CTNNAL1 alpha-CATU, CLLP ENSG00000119326 Catenin (cadherin-associated protein), alpha-like 1 9 108942569-109013529 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all adrenal gland: 264.1 -FAM206A C9orf6, CG-8, FLJ20457, Simiate ENSG00000119328 Family with sequence similarity 206, member A 9 108934181-108950744 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035917, HPA035918 Uncertain Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 36.3 -WDR34 bA216B9.3, DIC5, FAP133, MGC20486 ENSG00000119333 WD repeat domain 34 9 128633661-128656787 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040764, HPA041091 Approved Approved Cytosol Expressed in all testis: 53.0 -SET 2PP2A, IPP2A2, PHAPII ENSG00000119335 SET nuclear proto-oncogene 9 128683424-128696400 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005232, HPA063683 Supported Supported Nucleoplasm
Lipid droplets Expressed in all lymph node: 366.1 -PPP2R4 PR53, PTPA ENSG00000119383 Protein phosphatase 2A activator, regulatory subunit 4 9 129110950-129148946 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005695, CAB022068, CAB035999 Approved Validated Nucleoplasm
Cytosol Expressed in all parathyroid gland: 221.8 -GLE1 GLE1L, hGLE1, LCCS1 ENSG00000119392 GLE1 RNA export mediator 9 128504700-128542288 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041689, HPA043538, HPA061560 Supported Supported Nuclear membrane
Nucleoli Expressed in all testis: 58.6 -RAB14 FBP, RAB-14 ENSG00000119396 RAB14, member RAS oncogene family 9 121178137-121223014 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026419, CAB037066 Approved Supported Vesicles Expressed in all cerebral cortex: 83.6 -CNTRL CEP1, CEP110 ENSG00000119397 Centriolin 9 121074863-121177610 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020468, HPA020480, HPA051583 Approved Supported Centrosome
Cytosol Tissue enhanced 0 testis: 65.6 lymph node: 29.3 -TRIM32 BBS11, HT2A, LGMD2H, TATIP ENSG00000119401 Tripartite motif containing 32 9 116687302-116701300 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050060 Approved Approved Intermediate filaments Mixed fallopian tube: 21.0 -FBXW2 FBW2, Fwd2, Md6 ENSG00000119402 F-box and WD repeat domain containing 2 9 120751978-120793412 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067878 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 41.7 -PHF19 DKFZP727G051, MTF2L1, PCL3, TDRD19B ENSG00000119403 PHD finger protein 19 9 120855652-120894896 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed lymph node: 50.2 -NEK6 SID6-1512 ENSG00000119408 NIMA-related kinase 6 9 124257606-124353307 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045993, HPA056828 Approved Supported Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all appendix: 45.6 -BSPRY FLJ20150 ENSG00000119411 B-box and SPRY domain containing 9 113349541-113371233 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042889 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 parathyroid gland: 250.1 thyroid gland: 50.2 -PPP6C PP6 ENSG00000119414 Protein phosphatase 6, catalytic subunit 9 125146573-125189939 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050940 Uncertain Expressed in all thyroid gland: 52.4 -NDUFA8 MGC793, PGIV ENSG00000119421 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 9 122144058-122159819 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041510, HPA041600 Supported Validated Mitochondria Expressed in all heart muscle: 226.6 -HDHD3 C9orf158, MGC12904 ENSG00000119431 Haloacid dehalogenase-like hydrolase domain containing 3 9 113373419-113376999 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020427, HPA024158, HPA024585 Approved Supported Nucleoli Expressed in all adrenal gland: 87.2 -RBM18 MGC2734 ENSG00000119446 RNA binding motif protein 18 9 122237624-122264839 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057281 Uncertain Approved Nucleus
Nucleoli fibrillar center
Midbody Expressed in all breast: 20.2 -SLC46A2 Ly110, TSCOT ENSG00000119457 Solute carrier family 46, member 2 9 112878920-112890913 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA020098 Approved Group enriched 6 cervix, uterine: 23.0;endometrium: 5.5;epididymis: 5.4;lung: 15.2;skin: 11.3 seminal vesicle: 2.0 -HSDL2 C9orf99, SDR13C1 ENSG00000119471 Hydroxysteroid dehydrogenase like 2 9 112379937-112472410 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042890, HPA050453 Supported Supported Mitochondria Expressed in all adrenal gland: 79.7 -MAPKAP1 MGC2745, MIP1, SIN1 ENSG00000119487 Mitogen-activated protein kinase associated protein 1 9 125437393-125707234 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029091, HPA029092 Supported Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 79.4 -NR4A3 CHN, CSMF, MINOR, NOR1 ENSG00000119508 Nuclear receptor subfamily 4, group A, member 3 9 99821855-99866891 Cancer-related genes, Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA043360 Uncertain Tissue enhanced 0 adrenal gland: 89.5 urinary bladder: 43.5 -INVS NPHP2 ENSG00000119509 Inversin 9 100099256-100301000 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049994 Approved Cytosol Mixed parathyroid gland: 17.3 -GALNT12 GalNAc-T12 ENSG00000119514 Polypeptide N-acetylgalactosaminyltransferase 12 9 98807699-98850081 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048292 Supported Tissue enhanced 0 epididymis: 90.6 rectum: 62.3 -DENND1A FAM31A, FLJ21129, KIAA1608 ENSG00000119522 DENN/MADD domain containing 1A 9 123379654-123930152 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020481 Supported Nucleoplasm
Vesicles
Cytosol Expressed in all parathyroid gland: 21.5 -ALG2 CDGIi, FLJ14511, hALPG2, NET38 ENSG00000119523 ALG2, alpha-1,3/1,6-mannosyltransferase 9 99216426-99221956 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041512, HPA041601 Approved Validated Actin filaments
Cytosol Expressed in all epididymis: 75.8 -CSF3R CD114, GCSFR ENSG00000119535 Colony stimulating factor 3 receptor (granulocyte) 1 36466043-36483278 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB017116, HPA048086 Supported Tissue enhanced 0 appendix: 215.2;bone marrow: 243.8;placenta: 147.0 spleen: 98.2 -KDSR DHSR, FVT1, SDR35C1 ENSG00000119537 3-ketodihydrosphingosine reductase 18 63327726-63367510 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB003673, HPA044884 Approved Expressed in all cerebral cortex: 45.6 -VPS4B SKD1, SKD1B, VPS4-2 ENSG00000119541 Vacuolar protein sorting 4 homolog B (S. cerevisiae) 18 63389190-63422483 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040393, CAB046445, HPA057649 Approved Approved Vesicles
Intermediate filaments Expressed in all esophagus: 83.0 -ONECUT2 OC-2 ENSG00000119547 One cut homeobox 2 18 57435685-57491297 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA057058 Approved Supported Nucleoplasm
Actin filaments Tissue enhanced 0 duodenum: 10.6;gallbladder: 16.4 liver: 4.5 -C19orf25 FLJ36666 ENSG00000119559 Chromosome 19 open reading frame 25 19 1461143-1479556 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050270, HPA067491 Approved Approved Intermediate filaments Expressed in all cerebral cortex: 21.7 -ZBTB45 FLJ14486, ZNF499 ENSG00000119574 Zinc finger and BTB domain containing 45 19 58513530-58538911 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035754 Uncertain Approved Cytosol Expressed in all cerebral cortex: 10.6 -YLPM1 C14orf170, PPP1R169, ZAP ENSG00000119596 YLP motif containing 1 14 74763366-74859435 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048070, HPA061123 Uncertain Supported Nucleoplasm
Nuclear speckles Expressed in all testis: 39.0 -DCAF4 DKFZp434K114, WDR21, WDR21A ENSG00000119599 DDB1 and CUL4 associated factor 4 14 72926332-72959703 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047276 Approved Approved Nucleoplasm Expressed in all thyroid gland: 18.8 -PROX2 FLJ36749 ENSG00000119608 Prospero homeobox 2 14 74852871-74871940 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045057 Uncertain Mixed skin: 2.5 -VSX2 CHX10, HOX10, RET1 ENSG00000119614 Visual system homeobox 2 14 74239472-74262738 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level Evidence at protein level HPA003436 Uncertain Not detected testis: 0.2 -FCF1 Bka, C14orf111, CGI-35, UTP24 ENSG00000119616 FCF1 rRNA-processing protein 14 74713144-74738620 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046681 Approved Approved Nucleoplasm Expressed in all thyroid gland: 72.5 -PGF D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760 ENSG00000119630 Placental growth factor 14 74941834-74955784 Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041624 Approved Nucleoplasm
Mitochondria
Cytosol Tissue enhanced 0 placenta: 70.9;thyroid gland: 64.4 cervix: 29.9 -IFI27L2 FAM14A, TLH29 ENSG00000119632 Interferon, alpha-inducible protein 27-like 2 14 94127779-94130253 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA049588 Approved Nucleoli
Cytosol Expressed in all adrenal gland: 47.7 -BBOF1 C14orf45, CCDC176 ENSG00000119636 Basal body orientation factor 1 14 74019353-74082863 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003090, HPA003136 Uncertain Approved Nucleus
Plasma membrane
Microtubule organizing center Tissue enhanced 0 testis: 69.7 fallopian tube: 35.6 -NEK9 DKFZp434D0935, MGC16714, Nek8, NERCC ENSG00000119638 NIMA-related kinase 9 14 75079353-75127344 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001405 Approved Approved Mitochondria Expressed in all parathyroid gland: 30.1 -ACYP1 ENSG00000119640 Acylphosphatase 1, erythrocyte (common) type 14 75053221-75069483 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034944 Approved Approved Nucleus
Cytosol Expressed in all adrenal gland: 46.5 -IFT43 C14orf179, FLJ32173, MGC16028 ENSG00000119650 Intraflagellar transport 43 14 75902136-76084585 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003438 Approved Supported Microtubules
Microtubule organizing center Expressed in all fallopian tube: 97.9 -NPC2 EDDM1, HE1, NP-C2 ENSG00000119655 Niemann-Pick disease, type C2 14 74476192-74494177 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000835 Supported Tissue enriched 19 epididymis: 16057.0 lung: 850.5 -DNAL1 1700010H15RiK, C14orf168, CILD16, MGC12435 ENSG00000119661 Dynein, axonemal, light chain 1 14 73644875-73703732 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053129 Uncertain Approved Nucleus
Microtubule organizing center Expressed in all testis: 99.0 -IRF2BPL C14orf4, EAP1, KIAA1865 ENSG00000119669 Interferon regulatory factor 2 binding protein-like 14 77024543-77028699 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050862, HPA061333 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 36.1 -ACOT2 Mte1, ZAP128 ENSG00000119673 Acyl-CoA thioesterase 2 14 73567620-73575658 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043705 Approved Approved Mitochondria Expressed in all adipose tissue: 95.7 -LTBP2 C14orf141, LTBP3 ENSG00000119681 Latent transforming growth factor beta binding protein 2 14 74498170-74612378 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003415 Approved Approved Nucleus Mixed lung: 75.2 -AREL1 KIAA0317 ENSG00000119682 Apoptosis resistant E3 ubiquitin protein ligase 1 14 74653437-74713115 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051306 Uncertain Expressed in all testis: 33.7 -MLH3 ENSG00000119684 MutL homolog 3 14 75013764-75051532 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060570 Approved Nucleus Expressed in all parathyroid gland: 23.9 -TTLL5 KIAA0998 ENSG00000119685 Tubulin tyrosine ligase-like family member 5 14 75633625-75955078 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032128 Uncertain Approved Plasma membrane
Cytosol Tissue enriched 5 testis: 103.3 parathyroid gland: 20.2 -FLVCR2 C14orf58, FLJ20371, MFSD7C ENSG00000119686 Feline leukemia virus subgroup C cellular receptor family, member 2 14 75578617-75663214 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037984 Supported Tissue enhanced 0 testis: 38.5 small intestine: 27.4 -ABCD4 EST352188, P70R, PMP69, PXMP1L ENSG00000119688 ATP-binding cassette, sub-family D (ALD), member 4 14 74285423-74303056 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003396 Approved Expressed in all fallopian tube: 13.6 -DLST DLTS ENSG00000119689 Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 14 74881891-74903745 Citric acid cycle related proteins, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003010 Supported Expressed in all kidney: 106.0 -PPP4R4 CFAP14, KIAA1622, PP4R4 ENSG00000119698 Protein phosphatase 4, regulatory subunit 4 14 94146128-94279735 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041866, HPA050321 Uncertain Supported Cytosol Tissue enhanced 0 cerebral cortex: 14.0;testis: 11.1 ovary: 5.4 -TGFB3 ARVD, ARVD1 ENSG00000119699 Transforming growth factor, beta 3 14 75958099-75982991 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA063582 Approved Vesicles Mixed placenta: 84.3 -ZC2HC1C C14orf140, FAM164C ENSG00000119703 Zinc finger, C2HC-type containing 1C 14 75064170-75079987 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA050928 Uncertain Approved Nuclear speckles
Mitochondria Tissue enhanced 0 testis: 117.9 epididymis: 34.2 -SLIRP C14orf156, DC50 ENSG00000119705 SRA stem-loop interacting RNA binding protein 14 77708071-77761104 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020291 Approved Supported Mitochondria Expressed in all epididymis: 202.0 -RBM25 fSAP94, NET52, RNPC7, S164, Snu71 ENSG00000119707 RNA binding motif protein 25 14 73058436-73123898 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003025, HPA070713 Supported Validated Nuclear speckles Expressed in all testis: 53.7 -ALDH6A1 MMSDH ENSG00000119711 Aldehyde dehydrogenase 6 family, member A1 14 74056850-74084493 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029072, HPA029073, HPA029074, HPA029075 Supported Validated Mitochondria Expressed in all kidney: 386.6 -GPR68 OGR1 ENSG00000119714 G protein-coupled receptor 68 14 91232532-91253925 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed appendix: 8.4 -ESRRB DFNB35, ERR2, ERRb, ERRbeta, ESRL2, NR3B2 ENSG00000119715 Estrogen-related receptor beta 14 76310614-76501841 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 heart muscle: 2.5;kidney: 5.2;skeletal muscle: 1.7;stomach: 1.5;testis: 1.4 breast: 0.3 -EIF2B2 EIF-2Bbeta, EIF2B ENSG00000119718 Eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 14 75002911-75012366 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005841, CAB037105, HPA048028 Supported Approved Nucleoplasm
Plasma membrane
Focal adhesion sites Mixed thyroid gland: 19.4 -NRDE2 C14orf102, FLJ14051 ENSG00000119720 NRDE-2, necessary for RNA interference, domain containing 14 90267856-90332137 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047050, HPA050583 Uncertain Supported Nucleoplasm
Mitochondria Mixed endometrium: 2.7 -COQ6 CGI-10 ENSG00000119723 Coenzyme Q6 monooxygenase 14 73949926-73963670 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051371 Uncertain Expressed in all adrenal gland: 32.9 -ZNF410 APA-1, APA1 ENSG00000119725 Zinc finger protein 410 14 73886617-73932511 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA002871 Approved Nuclear bodies Expressed in all testis: 80.7 -RHOQ ARHQ, RASL7A, TC10 ENSG00000119729 Ras homolog family member Q 2 46541806-46583121 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044938 Approved Vesicles
Cytosol Expressed in all adipose tissue: 169.1 -GPR75 WI-31133 ENSG00000119737 G protein-coupled receptor 75 2 53852913-53859989 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 17.8 parathyroid gland: 6.4 -SUPT7L KIAA0764, SPT7L, STAF65, STAF65gamma ENSG00000119760 SPT7-like STAGA complex gamma subunit 2 27650812-27663840 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039565, HPA063643 Uncertain Approved Nucleoplasm Expressed in all endometrium: 45.3 -KLHL29 KBTBD9, KIAA1921 ENSG00000119771 Kelch-like family member 29 2 23385217-23708611 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049057, HPA057379 Approved Approved Mitochondria
Cytosol Mixed adrenal gland: 12.0 -DNMT3A ENSG00000119772 DNA (cytosine-5-)-methyltransferase 3 alpha 2 25227855-25342590 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009469, HPA026588 Approved Supported Nucleoplasm Expressed in all placenta: 22.6 -TMEM214 FLJ20254 ENSG00000119777 Transmembrane protein 214 2 27032910-27041695 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034551 Supported Endoplasmic reticulum
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 89.8 -ATAD2B KIAA1240 ENSG00000119778 ATPase family, AAA domain containing 2B 2 23748664-23927114 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034555 Uncertain Supported Nucleoplasm Mixed skin: 9.9 -FKBP1B FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase ENSG00000119782 FK506 binding protein 1B, 12.6 kDa 2 24049701-24063681 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051798, HPA057830 Uncertain Approved Microtubules Tissue enhanced 0 cerebral cortex: 24.5 duodenum: 19.2 -ATL2 ARL6IP2 ENSG00000119787 Atlastin GTPase 2 2 38294880-38377285 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029108 Approved Expressed in all thyroid gland: 100.9 -YPEL5 CGI-127 ENSG00000119801 Yippee-like 5 2 30146941-30160533 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042809 Approved Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 272.0 -FAM98A DKFZP564F0522 ENSG00000119812 Family with sequence similarity 98, member A 2 33583658-33599382 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036250, HPA036251 Uncertain Supported Vesicles Expressed in all parathyroid gland: 125.0 -YIPF4 FinGER4, MGC11061 ENSG00000119820 Yip1 domain family, member 4 2 32277910-32316594 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017884 Supported Supported Golgi apparatus
Vesicles
Plasma membrane Expressed in all cerebral cortex: 19.0 -AFTPH FLJ20080, FLJ23793, MGC33965, Nbla10388 ENSG00000119844 Aftiphilin 2 64524305-64593005 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034990, HPA034991 Approved Supported Golgi apparatus
Vesicles
Cytosol Expressed in all parathyroid gland: 64.5 -LGALSL GRP, HSPC159 ENSG00000119862 Lectin, galactoside-binding-like 2 64453969-64461381 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046079 Approved Approved Nucleoplasm Expressed in all skin: 111.1 -CNRIP1 C2orf32, CRIP1, CRIP1a, CRIP1b, DKFZP566K1924 ENSG00000119865 Cannabinoid receptor interacting protein 1 2 68284171-68320051 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035337 Approved Cytosol Tissue enhanced 0 cerebral cortex: 53.9 adipose tissue: 24.9 -BCL11A BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, ZNF856 ENSG00000119866 B-cell CLL/lymphoma 11A (zinc finger protein) 2 60451167-60553567 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB014891, HPA029003 Approved Validated Nucleoplasm
Nuclear bodies Tissue enhanced 0 skin: 41.0 tonsil: 31.8 -CRIPT HSPC139 ENSG00000119878 Cysteine-rich PDZ-binding protein 2 46616416-46625742 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046080, HPA056765 Approved Supported Nucleus
Nucleoli Expressed in all cerebral cortex: 25.5 -EPCAM 17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1 ENSG00000119888 Epithelial cell adhesion molecule 2 47345158-47387601 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003809, HPA026761, CAB030012, CAB055098, HPA067463 Supported Supported Plasma membrane Tissue enhanced 0 rectum: 691.1;small intestine: 728.8 colon: 672.2 -SLC17A5 AST, ISSD, NSD, SD, SIALIN, SIASD, SLD ENSG00000119899 Solute carrier family 17 (acidic sugar transporter), member 5 6 73593379-73654155 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044479 Supported Plasma membrane
Cytosol Tissue enriched 9 parathyroid gland: 640.5 thyroid gland: 69.8 -OGFRL1 dJ331H24.1 ENSG00000119900 Opioid growth factor receptor-like 1 6 71288803-71308950 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027122 Approved Nucleoplasm
Golgi apparatus Expressed in all cerebral cortex: 70.6 -SLF2 C10orf6, FAM178A, FLJ10512, FLJ25012 ENSG00000119906 SMC5-SMC6 complex localization factor 2 10 100912569-100965136 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038499, HPA057568 Approved Supported Nucleus
Vesicles Expressed in all epididymis: 56.6 -IDE ENSG00000119912 Insulin-degrading enzyme 10 92451684-92574076 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063478 Approved Expressed in all skin: 63.5 -TECTB ENSG00000119913 Tectorin beta 10 112283735-112305035 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 1.5 thyroid gland: 0.3 -ELOVL3 CIG-30 ENSG00000119915 ELOVL fatty acid elongase 3 10 102226328-102229589 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA036236 Supported Approved Vesicles
Cytosol Tissue enhanced 0 adipose tissue: 3.6;breast: 4.4;skin: 3.4 testis: 2.3 -IFIT3 CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, RIG-G ENSG00000119917 Interferon-induced protein with tetratricopeptide repeats 3 10 89327894-89340971 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059914 Approved Supported Mitochondria
Cytosol Expressed in all lung: 63.4 -NKX2-3 CSX3, NKX2.3, NKX2C, NKX4-3 ENSG00000119919 NK2 homeobox 3 10 99532933-99536524 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047561 Uncertain Uncertain Nucleoli
Cytosol Tissue enhanced 0 small intestine: 12.9;spleen: 30.1 duodenum: 11.8 -IFIT2 cig42, G10P2, GARG-39, IFI-54, IFI54, ISG-54K ENSG00000119922 Interferon-induced protein with tetratricopeptide repeats 2 10 89301955-89309276 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003408 Approved Approved Vesicles Mixed spleen: 39.8 -GPAM GPAT1, KIAA1560, MGC26846 ENSG00000119927 Glycerol-3-phosphate acyltransferase, mitochondrial 10 112149864-112215377 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046339, HPA060090 Approved Approved Mitochondria Expressed in all adipose tissue: 315.5 -CUTC CGI-32 ENSG00000119929 CutC copper transporter 10 99702558-99756134 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038619 Approved Supported Nucleoplasm
Cytosol Expressed in all skeletal muscle: 131.6 -PPP1R3C PPP1R5, PTG ENSG00000119938 Protein phosphatase 1, regulatory subunit 3C 10 91628442-91633054 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA027041 Uncertain Tissue enhanced 0 skeletal muscle: 322.8 heart muscle: 125.3 -PYROXD2 C10orf33, FLJ23849 ENSG00000119943 Pyridine nucleotide-disulphide oxidoreductase domain 2 10 98383565-98415184 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037566, HPA037567, HPA067394 Uncertain Approved Mitochondria Mixed fallopian tube: 15.2 -CNNM1 ACDP1 ENSG00000119946 Cyclin and CBS domain divalent metal cation transport mediator 1 10 99329099-99394330 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040408 Approved Uncertain Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 10.2;testis: 16.7 ovary: 3.0 -MXI1 bHLHc11, MAD2, MXD2, MXI ENSG00000119950 MAX interactor 1, dimerization protein 10 110207605-110287365 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035319, HPA056762 Approved Supported Nucleus
Nucleoli Expressed in all cerebral cortex: 88.4 -SMNDC1 SMNR, SPF30, TDRD16C ENSG00000119953 Survival motor neuron domain containing 1 10 110290730-110304951 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061214 Supported Nucleus
Nuclear bodies Expressed in all placenta: 26.1 -C10orf88 Em:AC073585.5, FLJ13490 ENSG00000119965 Chromosome 10 open reading frame 88 10 122930903-122954403 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039681, HPA040991 Approved Mixed testis: 14.3 -HELLS LSH, Nbla10143, PASG, SMARCA6 ENSG00000119969 Helicase, lymphoid-specific 10 94501434-94613905 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004491, HPA063242 Supported Approved Nucleus
Golgi apparatus
Vesicles Tissue enhanced 0 testis: 23.9 lymph node: 15.1 -PRLHR GPR10, PrRPR ENSG00000119973 Prolactin releasing hormone receptor 10 118589989-118595699 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039361 Supported Group enriched 7 adrenal gland: 6.5;cerebral cortex: 3.5;endometrium: 3.9;smooth muscle: 5.4 seminal vesicle: 0.7 -TCTN3 C10orf61, DKFZP564D116, JBTS18, TECT3 ENSG00000119977 Tectonic family member 3 10 95663396-95694143 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026987 Approved Approved Microtubules Expressed in all parathyroid gland: 135.3 -FAM45A ENSG00000119979 Family with sequence similarity 45, member A 10 119104086-119137984 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041159 Approved Plasma membrane
Centrosome
Cytosol Expressed in all thyroid gland: 31.7 -AVPI1 PP5395, VIP32, VIT32 ENSG00000119986 Arginine vasopressin-induced 1 10 97677424-97687323 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA037649 Approved Approved Nucleus
Plasma membrane Mixed adrenal gland: 42.4 -WDR11 BRWD2, DR11, FLJ10506, HH14, KIAA1351, WDR15 ENSG00000120008 WD repeat domain 11 10 120851175-120909524 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038980 Approved Approved Microtubules
Cytosol Mixed parathyroid gland: 45.7 -C10orf76 FLJ13114 ENSG00000120029 Chromosome 10 open reading frame 76 10 101845599-102056193 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA050913, HPA053580 Approved Approved Vesicles Expressed in all parathyroid gland: 25.9 -KCNIP2 KCHIP2 ENSG00000120049 Kv channel interacting protein 2 10 101825974-101843920 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA066717 Uncertain Vesicles Group enriched 7 adipose tissue: 238.4;cerebral cortex: 81.6;heart muscle: 150.4 testis: 23.9 -CFAP58 bA554P13.1, C10orf80, CCDC147, FLJ35908 ENSG00000120051 Cilia and flagella associated protein 58 10 104353764-104455090 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036555, HPA036556 Uncertain Approved Nucleus Group enriched 5 fallopian tube: 13.2;testis: 23.4 cervix: 3.3 -GOT1 AST1 ENSG00000120053 Glutamic-oxaloacetic transaminase 1, soluble 10 99396870-99430624 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064532, HPA072629 Supported Supported Nucleoplasm
Cytosol Expressed in all heart muscle: 340.8 -CPN1 ENSG00000120054 Carboxypeptidase N, polypeptide 1 10 100042193-100081877 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040323 Approved Nucleus
Nucleoli Tissue enriched 22 liver: 37.0 testis: 1.7 -SFRP5 SARP3 ENSG00000120057 Secreted frizzled-related protein 5 10 97766751-97771952 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 duodenum: 31.7;pancreas: 31.2;small intestine: 30.0 adrenal gland: 13.0 -GNA13 G13, MGC46138 ENSG00000120063 Guanine nucleotide binding protein (G protein), alpha 13 17 65010715-65056839 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010087 Approved Supported Cytosol Expressed in all bone marrow: 99.3 -HOXB8 HOX2, HOX2D ENSG00000120068 Homeobox B8 17 48611377-48614939 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA075905 Supported Nucleoplasm Tissue enhanced 0 epididymis: 67.4;seminal vesicle: 32.6 cervix: 16.9 -KANSL1 CENP-36, DKFZP727C091, KIAA1267, MSL1v1, NSL1 ENSG00000120071 KAT8 regulatory NSL complex subunit 1 17 46029916-46225374 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006874, HPA007208 Approved Supported Nucleoplasm Mixed testis: 29.8 -HOXB5 HOX2, HOX2A ENSG00000120075 Homeobox B5 17 48591257-48593961 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA074454 Supported Nucleus Tissue enhanced 0 epididymis: 20.8 fallopian tube: 11.0 -CRHR1 CRF-R, CRF1, CRHR ENSG00000120088 Corticotropin releasing hormone receptor 1 17 45784280-45835828 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 4.0 endometrium: 0.8 -HOXB3 HOX2, HOX2G ENSG00000120093 Homeobox B3 17 48548870-48604912 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level CAB009860, HPA064990 Approved Supported Nucleus Tissue enhanced 0 epididymis: 85.0 fallopian tube: 39.8 -HOXB1 HOX2, HOX2I ENSG00000120094 Homeobox B1 17 48528526-48530997 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level HPA044576 Uncertain Not detected testis: 0.3 -DUSP1 CL100, HVH1, MKP-1, PTPN10 ENSG00000120129 Dual specificity phosphatase 1 5 172768090-172771195 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB018554, HPA069577 Approved Approved Nucleoli
Cytosol Expressed in all thyroid gland: 1020.1 -PANK3 FLJ12899 ENSG00000120137 Pantothenate kinase 3 5 168548495-168579600 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062358 Approved Nucleoplasm
Golgi apparatus Expressed in all duodenum: 41.9 -MSX2 CRS2, FPP, HOX8, MSH, PFM, PFM1 ENSG00000120149 Msh homeobox 2 5 174724533-174730893 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005652 Uncertain Supported Nuclear speckles Tissue enhanced 0 placenta: 47.5 parathyroid gland: 16.4 -TEK CD202b, TIE-2, TIE2, VMCM, VMCM1 ENSG00000120156 TEK tyrosine kinase, endothelial 9 27109141-27230175 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010359, HPA073265 Approved Supported Plasma membrane
Microtubule organizing center Tissue enhanced 0 placenta: 65.3 lung: 42.7 -RCL1 RNAC, RPCL1 ENSG00000120158 RNA terminal phosphate cyclase-like 1 9 4792869-4885917 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071308 Approved Nucleoplasm Expressed in all liver: 122.9 -CAAP1 C9orf82, CAAP, FLJ13657 ENSG00000120159 Caspase activity and apoptosis inhibitor 1 9 26840685-26892804 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020404, HPA024029, HPA024100 Uncertain Approved Vesicles Expressed in all thyroid gland: 49.4 -EQTN AFAF, C9orf11, equatorin, SPACA8 ENSG00000120160 Equatorin, sperm acrosome associated 9 27284659-27297139 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA015089, HPA015504 Supported Tissue enriched 86 testis: 67.2 ovary: 0.7 -MOB3B C9orf35, FLJ13204, MOB1D, MOBKL2B ENSG00000120162 MOB kinase activator 3B 9 27325209-27529781 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057744 Uncertain Intermediate filaments
Cytosol Mixed ovary: 31.9 -INSL6 RIF1 ENSG00000120210 Insulin-like 6 9 5131979-5185668 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA021364 Supported Tissue enriched 38 testis: 21.7 placenta: 0.5 -INSL4 EPIL ENSG00000120211 Insulin-like 4 (placenta) 9 5231419-5235304 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 12 placenta: 22.2 epididymis: 1.8 -MLANA MART1 ENSG00000120215 Melan-A 9 5890802-5910606 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB000057, HPA048662 Supported Tissue enriched 21 skin: 50.5 breast: 2.3 -CD274 B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1 ENSG00000120217 CD274 molecule 9 5450503-5470566 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB030018 Approved Cytosol Mixed appendix: 14.4 -IFNA6 IFN-alphaK ENSG00000120235 Interferon, alpha 6 9 21349835-21351378 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected epididymis: 0.0 -IFNA8 IFN-alphaB ENSG00000120242 Interferon, alpha 8 9 21409147-21410185 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected adipose tissue: 0.0 -GRIA2 GluA2, GLUR2, GLURB ENSG00000120251 Glutamate receptor, ionotropic, AMPA 2 4 157204182-157366075 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006830, CAB007812, HPA008441, CAB012981 Supported Tissue enriched 8 cerebral cortex: 207.2 endometrium: 27.2 -NUP43 bA350J20.1, FLJ13287 ENSG00000120253 Nucleoporin 43kDa 6 149724315-149749665 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027126, HPA027291, HPA028500 Approved Expressed in all thyroid gland: 18.6 -MTHFD1L DKFZP586G1517, FLJ21145, FTHFSDC1 ENSG00000120254 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 6 150865549-151101887 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015006, HPA029040, HPA029041, HPA050052, HPA074911 Approved Supported Mitochondria Mixed placenta: 20.5 -LRP11 bA350J20.3, MANSC3 ENSG00000120256 Low density lipoprotein receptor-related protein 11 6 149818798-149864026 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA064002 Approved Mitochondria Expressed in all parathyroid gland: 88.0 -CCDC170 bA282P11.1, C6orf97, FLJ23305 ENSG00000120262 Coiled-coil domain containing 170 6 151494030-151621193 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027114, HPA027185 Supported Approved Golgi apparatus
Cell Junctions Tissue enriched 6 fallopian tube: 52.9 thyroid gland: 9.4 -PCMT1 ENSG00000120265 Protein-L-isoaspartate (D-aspartate) O-methyltransferase 6 149749443-149811420 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003239 Approved Supported Cytosol Expressed in all cerebral cortex: 195.3 -PLEKHG1 ARHGEF41, KIAA1209 ENSG00000120278 Pleckstrin homology domain containing, family G (with RhoGef domain) member 1 6 150599863-150843665 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027128, HPA027319, HPA028270 Approved Validated Nucleoplasm Tissue enhanced 0 spleen: 43.4 lymph node: 20.1 -MYCT1 FLJ21269, MTLC ENSG00000120279 Myc target 1 6 152697895-152724567 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047992 Uncertain Nucleoplasm Tissue enhanced 0 spleen: 69.9 placenta: 29.6 -CXorf21 FLJ11577 ENSG00000120280 Chromosome X open reading frame 21 X 30558824-30577844 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA001185 Uncertain Mixed appendix: 14.8 -MAGEB4 CT3.6, MGC33144 ENSG00000120289 Melanoma antigen family B4 X 30242052-30244193 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030456, CAB032794 Uncertain Group enriched 116 epididymis: 33.5;testis: 16.9 breast: 0.2 -CYSTM1 C5orf32, ORF1-FL49 ENSG00000120306 Cysteine-rich transmembrane module containing 1 5 140174642-140282052 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050930 Supported Expressed in all stomach: 482.5 -WDR55 FLJ20195, FLJ21702 ENSG00000120314 WD repeat domain 55 5 140664676-140674124 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043470, HPA048143 Uncertain Approved Nucleus
Nucleoli Expressed in all appendix: 13.1 -ARAP3 CENTD3, DRAG1, FLJ21065 ENSG00000120318 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 5 141653401-141682221 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042887 Uncertain Mixed placenta: 17.1 -PCDHB8 PCDH-BETA8, PCDH3I ENSG00000120322 Protocadherin beta 8 5 141177790-141180529 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057773 Uncertain Mixed endometrium: 2.1 -PCDHB10 ENSG00000120324 Protocadherin beta 10 5 141182560-141195642 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA013445, HPA014668, HPA029441 Approved Approved Vesicles
Plasma membrane Tissue enhanced 0 cerebral cortex: 8.3 endometrium: 5.1 -PCDHB14 PCDH-BETA14 ENSG00000120327 Protocadherin beta 14 5 141222932-141227759 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA007692, HPA045248 Uncertain Approved Vesicles Mixed parathyroid gland: 7.4 -PCDHB12 PCDH-BETA12 ENSG00000120328 Protocadherin beta 12 5 141208697-141212571 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045042 Uncertain Approved Plasma membrane Mixed endometrium: 3.6 -SLC25A2 ORNT2 ENSG00000120329 Solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 5 141302629-141304045 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA042146 Uncertain Tissue enriched 116 testis: 11.6 epididymis: 0.0 -TNN ENSG00000120332 Tenascin N 1 175067858-175148066 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010907, HPA026726, HPA026764 Uncertain Tissue enhanced 0 adipose tissue: 12.4 breast: 4.1 -MRPS14 HSMRPS14 ENSG00000120333 Mitochondrial ribosomal protein S14 1 175010789-175023425 Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051087 Uncertain Supported Nuclear membrane
Mitochondria Expressed in all thyroid gland: 38.8 -CENPL C1orf155, dJ383J4.3, FLJ31044 ENSG00000120334 Centromere protein L 1 173799550-173824720 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044520 Uncertain Tissue enhanced 0 testis: 18.1 lymph node: 7.9 -TNFSF18 AITRL, hGITRL, TL6 ENSG00000120337 Tumor necrosis factor (ligand) superfamily, member 18 1 173039960-173050963 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA012699 Uncertain Tissue enhanced 0 cerebral cortex: 2.9;gallbladder: 3.1 parathyroid gland: 1.4 -SEC16B LZTR2, PGPR-p117, RGPR, Sec16S ENSG00000120341 SEC16 homolog B, endoplasmic reticulum export factor 1 177923956-177984303 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031202, HPA054292 Uncertain Approved Endoplasmic reticulum
Plasma membrane
Actin filaments Tissue enhanced 0 duodenum: 28.9;small intestine: 31.5 liver: 18.8 -GORAB FLJ11752, GO, NTKL-BP1, SCYL1BP1 ENSG00000120370 Golgin, RAB6-interacting 1 170532129-170553446 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027208, HPA027250 Approved Validated Nucleus
Golgi apparatus
Cytosol Mixed thyroid gland: 7.9 -GPR31 12-HETER, HETER1 ENSG00000120436 G protein-coupled receptor 31 6 167156271-167158329 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014014, HPA027108 Uncertain Tissue enhanced 0 lymph node: 1.6 spleen: 0.9 -ACAT2 ENSG00000120437 Acetyl-CoA acetyltransferase 2 6 159760328-159779055 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021106, HPA025736, HPA025765, HPA025811 Supported Supported Nucleus
Cytosol Mixed liver: 45.9 -TCP1 CCT1, Ccta, D6S230E ENSG00000120438 T-complex 1 6 159778498-159789749 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017460, HPA027337, HPA031082 Approved Expressed in all testis: 323.1 -TTLL2 C6orf104, dJ366N23.3, NYD-TSPG ENSG00000120440 Tubulin tyrosine ligase-like family member 2 6 167325086-167359503 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA027985 Approved Nuclear membrane
Nucleoli Tissue enriched 58 testis: 33.9 liver: 0.5 -SNX19 CHET8, KIAA0254 ENSG00000120451 Sorting nexin 19 11 130875436-130916509 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013447 Uncertain Supported Mitochondria Expressed in all testis: 51.6 -KCNJ5 CIR, GIRK4, KATP1, Kir3.4, LQT13 ENSG00000120457 Potassium channel, inwardly rectifying subfamily J, member 5 11 128891356-128921035 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014722, HPA017353, CAB022569 Supported Tissue enhanced 0 adrenal gland: 85.2 spleen: 19.1 -MSANTD2 C11orf61, FLJ23342 ENSG00000120458 Myb/SANT-like DNA-binding domain containing 2 11 124766498-124800673 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038694, HPA038695 Approved Supported Nucleoplasm
Nuclear bodies Mixed thyroid gland: 14.6 -TP53AIP1 p53AIP1 ENSG00000120471 Tumor protein p53 regulated apoptosis inducing protein 1 11 128934731-128943399 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044300, HPA048797 Approved Tissue enhanced 0 esophagus: 6.3;skin: 22.2 fallopian tube: 4.0 -TEX11 TGC1, TSGA3 ENSG00000120498 Testis expressed 11 X 70528940-70908731 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002950 Approved Group enriched 10 pancreas: 12.3;testis: 21.1 rectum: 1.7 -ARR3 ARRX ENSG00000120500 Arrestin 3, retinal (X-arrestin) X 70268305-70281840 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed skin: 2.7 -PDZD11 PDZK11 ENSG00000120509 PDZ domain containing 11 X 70286595-70290514 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003972 Approved Expressed in all cerebral cortex: 60.1 -SLC10A7 C4orf13, DKFZp313H0531, DKFZp566M114, DKFZp779O2438, MGC25043 ENSG00000120519 Solute carrier family 10, member 7 4 146253975-146521964 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039996, HPA057906 Uncertain Approved Nucleoli Mixed epididymis: 16.0 -NUDCD1 CML66, FLJ14991 ENSG00000120526 NudC domain containing 1 8 109240919-109334385 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023183 Uncertain Supported Nucleoplasm
Cytosol Mixed testis: 24.0 -ENY2 DC6, FLJ20480, Sus1 ENSG00000120533 Enhancer of yellow 2 homolog (Drosophila) 8 109334324-109345953 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024648 Approved Approved Nucleoplasm
Mitochondria Expressed in all kidney: 77.0 -MASTL FLJ14813, Gwl, THC2 ENSG00000120539 Microtubule associated serine/threonine kinase-like 10 27154824-27186924 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027175, HPA054273 Approved Validated Nucleoplasm Mixed testis: 12.6 -KIAA1217 DKFZP761L0424, SKT ENSG00000120549 KIAA1217 10 23694746-24547848 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004941 Approved Approved Nucleus
Cytosol Mixed parathyroid gland: 86.3 -LYZL1 LYC2, MGC33408 ENSG00000120563 Lysozyme-like 1 10 29289061-29318328 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 139 testis: 53.2 epididymis: 0.3 -PLXDC2 FLJ14623, TEM7R ENSG00000120594 Plexin domain containing 2 10 19816239-20289856 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017268, HPA070793 Approved Supported Nuclear bodies Mixed gallbladder: 25.1 -EPC1 Epl1 ENSG00000120616 Enhancer of polycomb homolog 1 (Drosophila) 10 32267751-32378798 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all endometrium: 32.6 -IQSEC3 KIAA1110, MGC30156 ENSG00000120645 IQ motif and Sec7 domain 3 12 66765-178460 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 16.2 fallopian tube: 5.4 -CCDC77 MGC13183 ENSG00000120647 Coiled-coil domain containing 77 12 389273-442645 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038854 Approved Approved Nuclear membrane Mixed testis: 23.3 -TAF12 TAF2J, TAFII20 ENSG00000120656 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 1 28589323-28643085 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008519 Approved Expressed in all testis: 36.9 -ENOX1 cCNOX, CNOX, FLJ10094, PIG38 ENSG00000120658 Ecto-NOX disulfide-thiol exchanger 1 13 43213518-43786908 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038355 Approved Supported Plasma membrane Tissue enhanced 0 testis: 18.1 cerebral cortex: 11.5 -TNFSF11 CD254, ODF, OPGL, RANKL, TRANCE ENSG00000120659 Tumor necrosis factor (ligand) superfamily, member 11 13 42562736-42608013 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB009193, HPA045142 Supported Tissue enhanced 0 lymph node: 17.6 appendix: 6.5 -MTRF1 MGC47721, MTTRF1, RF1 ENSG00000120662 Mitochondrial translational release factor 1 13 41216369-41263577 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043316 Uncertain Expressed in all testis: 25.1 -SOHLH2 bHLHe81, FLJ20449, SPATA28, TEB1 ENSG00000120669 Spermatogenesis and oogenesis specific basic helix-loop-helix 2 13 36168208-36214615 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029182, HPA029183 Uncertain Vesicles Tissue enriched 13 testis: 46.0 prostate: 3.5 -DNAJC15 DNAJD1, MCJ ENSG00000120675 DnaJ (Hsp40) homolog, subfamily C, member 15 13 43023203-43114224 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 11.4 -PROSER1 bA50D16.2, C13orf23, FLJ12661 ENSG00000120685 Proline and serine rich 1 13 39009866-39038076 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034225, HPA055687 Uncertain Approved Nucleus
Cytosol Expressed in all placenta: 30.0 -UFM1 bA131P10.1, C13orf20 ENSG00000120686 Ubiquitin-fold modifier 1 13 38349849-38363619 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039758 Approved Expressed in all endometrium: 101.0 -WBP4 FBP21, MGC117310 ENSG00000120688 WW domain binding protein 4 13 41061274-41084006 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038965, HPA058738 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Expressed in all endometrium: 27.5 -ELF1 ENSG00000120690 E74-like factor 1 (ets domain transcription factor) 13 40931920-41061440 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001755, CAB005172 Approved Supported Nucleoplasm Expressed in all bone marrow: 133.1 -SMAD9 MADH6, MADH9 ENSG00000120693 SMAD family member 9 13 36844831-36920765 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009119, HPA031162 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 thyroid gland: 62.6 prostate: 22.6 -HSPH1 HSP105A, HSP105B, KIAA0201, NY-CO-25 ENSG00000120694 Heat shock 105kDa/110kDa protein 1 13 31134974-31162388 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002060, HPA028675, HPA031569 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 123.1 -KBTBD7 DKFZP434E2318 ENSG00000120696 Kelch repeat and BTB (POZ) domain containing 7 13 41189833-41194566 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043709, HPA046861, HPA048914 Uncertain Mixed cerebral cortex: 11.0 -ALG5 bA421P11.2 ENSG00000120697 ALG5, dolichyl-phosphate beta-glucosyltransferase 13 36949775-37000261 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007989 Approved Approved Cytosol Expressed in all thyroid gland: 96.2 -EXOSC8 bA421P11.3, CIP3, EAP2, OIP2, p9, RRP43, Rrp43p ENSG00000120699 Exosome component 8 13 36998816-37009613 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034240, HPA039702, HPA043942 Uncertain Approved Mitochondria Expressed in all testis: 48.4 -ETF1 ERF, ERF1, RF1, SUP45L1, TB3-1 ENSG00000120705 Eukaryotic translation termination factor 1 5 138506095-138543300 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011686, HPA037511 Approved Expressed in all testis: 108.1 -TGFBI BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1 ENSG00000120708 Transforming growth factor, beta-induced, 68kDa 5 136028895-136063818 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008612, HPA017019 Supported Approved Cytosol Expressed in all placenta: 606.0 -FAM53C C5orf6 ENSG00000120709 Family with sequence similarity 53, member C 5 138331935-138349729 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042796 Approved Expressed in all testis: 73.3 -SIL1 BAP, MSS, ULG5 ENSG00000120725 SIL1 nucleotide exchange factor 5 138946720-139293557 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011949 Supported Expressed in all thyroid gland: 59.8 -PAIP2 PAIP2A ENSG00000120727 Poly(A) binding protein interacting protein 2 5 139341587-139369720 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035945, CAB037212, HPA056766 Approved Approved Vesicles Expressed in all testis: 305.1 -MYOT LGMD1, LGMD1A, TTID ENSG00000120729 Myotilin 5 137867791-137887851 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037733, HPA037734 Supported Tissue enriched 21 skeletal muscle: 767.1 esophagus: 36.2 -KDM3B C5orf7, JMJD1B, KIAA1082, NET22 ENSG00000120733 Lysine (K)-specific demethylase 3B 5 138352596-138437028 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016610, HPA057202 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 66.5 -EGR1 AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 ENSG00000120738 Early growth response 1 5 138465490-138469315 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB019427, HPA029937, HPA029938 Supported Validated Nucleoplasm Expressed in all ovary: 1184.1 -SERP1 FLJ43424, RAMP4 ENSG00000120742 Stress-associated endoplasmic reticulum protein 1 3 150541994-150603228 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038970 Approved Approved Endoplasmic reticulum Expressed in all epididymis: 179.5 -PLS1 I-plastin, Plastin-1 ENSG00000120756 Plastin 1 3 142596387-142713664 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055744 Supported Tissue enhanced 0 duodenum: 197.8;small intestine: 355.4 rectum: 154.7 -ZFP30 KIAA0961, ZNF745 ENSG00000120784 ZFP30 zinc finger protein 19 37613749-37692337 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA030606 Uncertain Approved Cytosol Mixed testis: 14.2 -NR2C1 TR2, TR2-11 ENSG00000120798 Nuclear receptor subfamily 2, group C, member 1 12 95020229-95073703 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035040, HPA035041, HPA067767 Supported Supported Nucleus
Cell Junctions
Cytosol Mixed testis: 21.8 -UTP20 1A6/DRIM, DRIM ENSG00000120800 UTP20 small subunit (SSU) processome component 12 101280109-101386616 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049341 Supported Nucleoli
Plasma membrane Mixed parathyroid gland: 12.2 -TMPO LAP2, LEMD4, TP ENSG00000120802 Thymopoietin 12 98515512-98550379 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008150, CAB009847 Supported Validated Nuclear membrane Expressed in all lymph node: 92.4 -ARL1 ARFL1 ENSG00000120805 ADP-ribosylation factor-like 1 12 101393120-101407820 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062656, HPA073012 Approved Supported Golgi apparatus Expressed in all thyroid gland: 141.5 -GLT8D2 FLJ31494 ENSG00000120820 Glycosyltransferase 8 domain containing 2 12 103988984-104064183 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026904 Approved Approved Cytosol Mixed gallbladder: 57.3 -MTERF2 FLJ14062, MTERFD3 ENSG00000120832 Mitochondrial transcription termination factor 2 12 106977291-106987166 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003526 Approved Expressed in all adrenal gland: 29.3 -SOCS2 CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2 ENSG00000120833 Suppressor of cytokine signaling 2 12 93569814-93583487 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010356 Approved Approved Endoplasmic reticulum Expressed in all smooth muscle: 129.0 -NFYB CBF-A, HAP3, NF-YB ENSG00000120837 Nuclear transcription factor Y, beta 12 104117077-104138289 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004211 Supported Supported Nucleoplasm Expressed in all seminal vesicle: 122.9 -CCDC53 CGI-116 ENSG00000120860 Coiled-coil domain containing 53 12 102012927-102062149 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038338, HPA038339 Approved Approved Vesicles Expressed in all testis: 164.4 -APAF1 APAF-1, CED4 ENSG00000120868 Apoptotic peptidase activating factor 1 12 98645141-98735433 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031373, CAB069399 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Mixed bone marrow: 21.7 -DUSP4 HVH2, MKP-2, TYP ENSG00000120875 Dual specificity phosphatase 4 8 29333064-29350668 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061967 Supported Nucleoplasm Tissue enhanced 0 breast: 29.4 stomach: 28.1 -CLU APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2 ENSG00000120885 Clusterin 8 27596917-27615031 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000476, HPA000572, CAB016253 Uncertain Expressed in all epididymis: 10967.7 -TNFRSF10B CD262, DR5, KILLER, TRAIL-R2, TRICK2A, TRICKB ENSG00000120889 Tumor necrosis factor receptor superfamily, member 10b 8 23020133-23069179 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023625 Approved Expressed in all gallbladder: 33.4 -SORBS3 SCAM-1, SH3D4, vinexin ENSG00000120896 Sorbin and SH3 domain containing 3 8 22544986-22575788 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015849, HPA048034 Approved Approved Nucleoplasm
Focal adhesion sites Expressed in all cervix: 95.0 -PTK2B CADTK, CAKB, FAK2, PTK, PYK2, RAFTK ENSG00000120899 Protein tyrosine kinase 2 beta 8 27311482-27459391 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003850, HPA026091, HPA026276 Approved Validated Plasma membrane
Cytosol Expressed in all lymph node: 100.2 -CHRNA2 ENSG00000120903 Cholinergic receptor, nicotinic, alpha 2 (neuronal) 8 27459761-27479883 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 20 prostate: 43.0 breast: 2.1 -ADRA1A ADRA1C, ADRA1L1 ENSG00000120907 Adrenoceptor alpha 1A 8 26748150-26867273 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029678, HPA029679 Approved Tissue enhanced 0 adipose tissue: 22.6;liver: 32.0 seminal vesicle: 19.5 -PPP3CC CALNA3, PP2Bgamma ENSG00000120910 Protein phosphatase 3, catalytic subunit, gamma isozyme 8 22440819-22541142 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023396, CAB024950 Approved Approved Vesicles Expressed in all testis: 101.2 -PDLIM2 ENSG00000120913 PDZ and LIM domain 2 (mystique) 8 22578279-22598025 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003880 Approved Approved Actin filaments
Focal adhesion sites Expressed in all spleen: 273.0 -EPHX2 ENSG00000120915 Epoxide hydrolase 2, cytoplasmic 8 27490779-27545564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023094, HPA023660 Approved Validated Cytosol Expressed in all kidney: 170.3 -RNF170 ADSA, DKFZP564A022, SNAX1 ENSG00000120925 Ring finger protein 170 8 42849637-42897290 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050931, HPA054621 Uncertain Expressed in all thyroid gland: 47.6 -NPPB ENSG00000120937 Natriuretic peptide B 1 11857464-11858931 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 1602 heart muscle: 2863.6 testis: 1.7 -UBIAD1 SCCD, TERE1 ENSG00000120942 UbiA prenyltransferase domain containing 1 1 11273206-11296049 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044862 Approved Vesicles Expressed in all fallopian tube: 15.7 -TARDBP ALS10, TDP-43 ENSG00000120948 TAR DNA binding protein 1 11012344-11026420 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003703, HPA017284 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 129.0 -TNFRSF8 CD30, D1S166E, KI-1 ENSG00000120949 Tumor necrosis factor receptor superfamily, member 8 1 12063377-12144207 Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000016, HPA032081, HPA032082 Approved Tissue enhanced 0 appendix: 4.3 adipose tissue: 3.1 -PRAMEF2 FLJ43580 ENSG00000120952 PRAME family member 2 1 12857086-12861909 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.2 -ZNF706 HSPC038 ENSG00000120963 Zinc finger protein 706 8 101177878-101206193 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042793 Approved Plasma membrane Expressed in all skin: 159.7 -LYPLA1 LPL1 ENSG00000120992 Lysophospholipase I 8 54046367-54102017 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050941, HPA063151 Supported Uncertain Nucleoplasm
Cytosol Expressed in all testis: 118.0 -CRISPLD1 Cocoacrisp, DKFZp762F133, LCRISP1 ENSG00000121005 Cysteine-rich secretory protein LCCL domain containing 1 8 74984515-75034558 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024725 Uncertain Tissue enhanced 0 prostate: 40.7 breast: 34.9 -COPS5 CSN5, JAB1, MOV-34, SGN5 ENSG00000121022 COP9 signalosome subunit 5 8 67043079-67083783 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004242, HPA004845, HPA051531 Supported Validated Nucleoplasm Expressed in all testis: 92.0 -RDH10 SDR16C4 ENSG00000121039 Retinol dehydrogenase 10 (all-trans) 8 73294612-73325281 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049199 Approved Lipid droplets Expressed in all placenta: 51.3 -EPX EPO, EPP, EPX-PEN ENSG00000121053 Eosinophil peroxidase 17 58192737-58205174 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050507 Approved Tissue enriched 14 bone marrow: 20.6 fallopian tube: 1.4 -AKAP1 AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, S-AKAP84, SAKAP84, TDRD17 ENSG00000121057 A kinase (PRKA) anchor protein 1 17 57085092-57121349 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008620, HPA008691, CAB019286 Supported Supported Mitochondria Expressed in all testis: 149.4 -COIL CLN80, p80-coilin ENSG00000121058 Coilin 17 56938187-56961054 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017524, HPA027885, HPA068537, CAB069400 Supported Validated Nucleus
Nucleoli fibrillar center
Nuclear bodies Tissue enriched 9 testis: 174.4 thyroid gland: 20.1 -TRIM25 EFP, RNF147, ZNF147 ENSG00000121060 Tripartite motif containing 25 17 56887909-56914038 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005909 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all skin: 34.9 -SCPEP1 RISC ENSG00000121064 Serine carboxypeptidase 1 17 56978105-57006768 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039102, HPA057200 Approved Approved Golgi apparatus Expressed in all parathyroid gland: 610.1 -SPOP BTBD32, TEF2 ENSG00000121067 Speckle-type POZ protein 17 49598884-49678234 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all smooth muscle: 120.3 -TBX2 ENSG00000121068 T-box 2 17 61399896-61409466 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008586, CAB013636 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 lung: 50.2 seminal vesicle: 39.7 -SLC35B1 UGTREL1 ENSG00000121073 Solute carrier family 35, member B1 17 49700943-49709014 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048655, HPA057418 Approved Approved Nucleus
Endoplasmic reticulum
Vesicles Expressed in all thyroid gland: 52.0 -TBX4 ENSG00000121075 T-box 4 17 61452404-61485110 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB032413, HPA044457, HPA050669 Uncertain Supported Vesicles Group enriched 6 lung: 43.9;placenta: 29.7;prostate: 13.1 urinary bladder: 4.9 -TEX14 CT113 ENSG00000121101 Testis expressed 14 17 58556678-58692055 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030620 Approved Vesicles
Plasma membrane
Cell Junctions
Cytosol Tissue enriched 43 testis: 49.0 bone marrow: 1.1 -FAM117A ENSG00000121104 Family with sequence similarity 117, member A 17 49710332-49789180 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022531 Approved Approved Nucleoplasm Expressed in all spleen: 47.4 -NCAPH BRRN1, CAP-H, hCAP-H ENSG00000121152 Non-SMC condensin I complex, subunit H 2 96335787-96373845 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002647, HPA003008 Supported Supported Nucleus
Cytosol Tissue enhanced 0 testis: 55.2 lymph node: 21.5 -LRAT LCA14 ENSG00000121207 Lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 4 154626945-154753118 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008397, HPA070726 Uncertain Uncertain Endoplasmic reticulum
Golgi apparatus Mixed thyroid gland: 2.3 -KIAA0922 DKFZp586H1322, TMEM131L ENSG00000121210 KIAA0922 4 153466346-153636711 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043472, HPA048443 Uncertain Approved Nucleoli fibrillar center
Vesicles Expressed in all lymph node: 57.0 -MND1 GAJ ENSG00000121211 Meiotic nuclear divisions 1 4 153344649-153415118 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 testis: 28.6 lymph node: 14.4 -TRIM6 RNF89 ENSG00000121236 Tripartite motif containing 6 11 5596109-5612958 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060514 Uncertain Tissue enhanced 0 kidney: 22.3 testis: 17.2 -ABCC11 MRP8 ENSG00000121270 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 16 48166910-48247568 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031980, HPA031981, HPA031982, CAB032513 Uncertain Tissue enriched 11 breast: 63.2 prostate: 5.5 -PAPD5 TRF4-2 ENSG00000121274 PAP associated domain containing 5 16 50152918-50235310 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042968, HPA048225 Uncertain Expressed in all parathyroid gland: 27.1 -ADCY7 AC7, KIAA0037 ENSG00000121281 Adenylate cyclase 7 16 50246137-50318135 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041218, HPA048241 Uncertain Approved Cytosol Mixed spleen: 42.9 -CEP89 CCDC123, FLJ14640 ENSG00000121289 Centrosomal protein 89kDa 19 32875925-32971991 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039382, HPA040056 Uncertain Supported Plasma membrane
Cytosol Mixed fallopian tube: 14.8 -TSHZ3 KIAA1474, TSH3, ZNF537 ENSG00000121297 Teashirt zinc finger homeobox 3 19 31274945-31349547 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008834 Approved Supported Nucleoplasm Mixed ovary: 37.4 -ECHDC2 FLJ10948 ENSG00000121310 Enoyl CoA hydratase domain containing 2 1 52895910-52927212 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026731, HPA026768 Supported Uncertain Mitochondria Tissue enhanced 0 liver: 47.9 kidney: 26.3 -TAS2R8 T2R8, TRB5 ENSG00000121314 Taste receptor, type 2, member 8 12 10806051-10807293 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.0 -PLBD1 FLJ22662 ENSG00000121316 Phospholipase B domain containing 1 12 14503661-14568349 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040303 Approved Expressed in all bone marrow: 167.6 -TAS2R10 T2R10, TRB2 ENSG00000121318 Taste receptor, type 2, member 10 12 10825317-10826358 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.2 -PRB2 cP7, PRPPRB1, Ps ENSG00000121335 Proline-rich protein BstNI subfamily 2 12 11391540-11501041 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 4645 salivary gland: 4981.5 testis: 1.0 -PYROXD1 DKFZp762G094, FLJ22028 ENSG00000121350 Pyridine nucleotide-disulphide oxidoreductase domain 1 12 21437615-21471252 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038319, HPA038320 Uncertain Approved Nuclear speckles Expressed in all thyroid gland: 26.7 -IAPP AMYLIN, DAP, IAP ENSG00000121351 Islet amyloid polypeptide 12 21354959-21379978 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB000352, HPA053194 Supported Tissue enriched 7 pancreas: 35.0 testis: 5.3 -KCNJ8 Kir6.1 ENSG00000121361 Potassium channel, inwardly rectifying subfamily J, member 8 12 21764955-21775581 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031066 Uncertain Mixed seminal vesicle: 31.6 -TAS2R7 T2R7, TRB4 ENSG00000121377 Taste receptor, type 2, member 7 12 10801532-10802627 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.0 -BCL2L14 BCL-G, BCLG ENSG00000121380 BCL2-like 14 (apoptosis facilitator) 12 12049844-12211084 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040665 Approved Uncertain Cytosol Tissue enhanced 0 rectum: 17.2;testis: 24.0 small intestine: 14.4 -TAS2R9 T2R9, TRB6 ENSG00000121381 Taste receptor, type 2, member 9 12 10809137-10810168 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.0 -PSPC1 FLJ10955, PSP1 ENSG00000121390 Paraspeckle component 1 13 19674752-19783019 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038904 Supported Approved Nucleoplasm
Nucleoli fibrillar center Expressed in all testis: 45.2 -ZNF549 FLJ34917 ENSG00000121406 Zinc finger protein 549 19 57527325-57557542 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA039511 Uncertain Approved Nucleoplasm
Cytosol Mixed parathyroid gland: 10.2 -A1BG ENSG00000121410 Alpha-1-B glycoprotein 19 58345178-58353499 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016673, HPA044252 Supported Tissue enriched 297 liver: 505.4 fallopian tube: 1.7 -ZSCAN18 FLJ12895, ZNF447 ENSG00000121413 Zinc finger and SCAN domain containing 18 19 58083838-58118427 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024318 Supported Approved Nucleoplasm Expressed in all cerebral cortex: 78.9 -ZNF211 CH2H2-25, ZNF-25 ENSG00000121417 Zinc finger protein 211 19 57630395-57642779 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA011340, HPA049967 Approved Approved Mitochondria
Rods & Rings Expressed in all parathyroid gland: 32.1 -PDZRN3 KIAA1095, LNX3, SEMACAP3 ENSG00000121440 PDZ domain containing ring finger 3 3 73382433-73624940 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038822, HPA061420 Approved Supported Nucleus
Cytosol Mixed ovary: 85.8 -RGSL1 RGSL2 ENSG00000121446 Regulator of G-protein signaling like 1 1 182409192-182560599 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 testis: 9.1 epididymis: 1.4 -LHX4 Gsh4 ENSG00000121454 LIM homeobox 4 1 180230286-180278982 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA055705 Approved Nuclear speckles Mixed testis: 2.5 -RNF2 BAP-1, BAP1, DING, HIPI3, RING1B, RING2 ENSG00000121481 Ring finger protein 2 1 185045364-185102608 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026803 Uncertain Validated Nucleoplasm
Nuclear bodies Expressed in all testis: 42.0 -TRMT1L C1orf25 ENSG00000121486 TRNA methyltransferase 1-like 1 185118098-185157072 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026728 Uncertain Approved Nucleus
Nucleoli Mixed testis: 50.1 -SEC22A SEC22L2 ENSG00000121542 SEC22 homolog A, vesicle trafficking protein 3 123201927-123274130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 48.4 -CSTA STF1, STFA ENSG00000121552 Cystatin A (stefin A) 3 122325244-122341972 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000469, HPA001031, CAB047315 Supported Uncertain Nucleus
Cytosol Group enriched 6 esophagus: 3891.8;tonsil: 868.8 skin: 429.9 -DPPA4 FLJ10713 ENSG00000121570 Developmental pluripotency associated 4 3 109326141-109337572 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020678, HPA035249, HPA035250 Supported Group enriched 8 bone marrow: 2.8;placenta: 3.0;testis: 7.7 tonsil: 0.5 -POPDC2 POP2 ENSG00000121577 Popeye domain containing 2 3 119636457-119665324 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024255 Supported Tissue enhanced 0 heart muscle: 191.4;seminal vesicle: 63.4 smooth muscle: 35.0 -B4GALT4 beta4Gal-T4 ENSG00000121578 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 3 119211732-119241103 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046819, HPA063546 Approved Supported Golgi apparatus Expressed in all epididymis: 74.6 -NAA50 FLJ13194, MAK3, NAT13, NAT5, San ENSG00000121579 N(alpha)-acetyltransferase 50, NatE catalytic subunit 3 113716460-113746300 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all skeletal muscle: 111.8 -CD80 B7-1, B7.1, CD28LG, CD28LG1 ENSG00000121594 CD80 molecule 3 119524293-119559602 CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB025368, HPA050092 Supported Tissue enhanced 0 appendix: 7.4;lymph node: 6.8;tonsil: 6.1 spleen: 4.6 -KIF18A DKFZP434G2226, PPP1R99 ENSG00000121621 Kinesin family member 18A 11 28020620-28108308 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039312, HPA039484 Approved Supported Microtubules
Cytokinetic bridge Tissue enhanced 0 testis: 23.3 lymph node: 5.3 -GJA8 CAE, CAE1, CX50, CZP1 ENSG00000121634 Gap junction protein, alpha 8, 50kDa 1 147907956-147909257 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 91 testis: 12.0 smooth muscle: 0.1 -DESI2 C1orf121, CGI-146, FAM152A, FLJ21998, PNAS-4, PPPDE1 ENSG00000121644 Desumoylating isopeptidase 2 1 244652935-244709033 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049950 Approved Vesicles Expressed in all testis: 94.5 -MAPK8IP1 IB1, JIP-1, JIP1, PRKM8IP ENSG00000121653 Mitogen-activated protein kinase 8 interacting protein 1 11 45885651-45906465 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA058921, HPA070332 Supported Plasma membrane Tissue enriched 5 cerebral cortex: 177.7 parathyroid gland: 32.6 -CRY2 ENSG00000121671 Cryptochrome circadian clock 2 11 45847118-45883248 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037577 Supported Supported Nuclear speckles
Cytosol Expressed in all cerebral cortex: 56.4 -PEX16 ENSG00000121680 Peroxisomal biogenesis factor 16 11 45909669-45918812 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043286 Approved Expressed in all cerebral cortex: 27.5 -DEPDC7 ENSG00000121690 DEP domain containing 7 11 33015864-33033582 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015800 Approved Nucleus
Nucleoli
Cytosol Tissue enhanced 0 liver: 37.5;testis: 50.4 small intestine: 31.9 -CAT ENSG00000121691 Catalase 11 34438925-34472062 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001515, HPA051282, HPA055838 Supported Supported Vesicles
Cytosol Expressed in all liver: 624.4 -PILRB FDFACT1, FDFACT2 ENSG00000121716 Paired immunoglobin-like type 2 receptor beta 7 100352176-100367733 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA026750 Approved Approved Mitochondria Expressed in all testis: 167.1 -ZMYM2 FIM, MYM, RAMP, ZNF198 ENSG00000121741 Zinc finger, MYM-type 2 13 19958670-20091829 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031765 Approved Approved Nucleoplasm
Endoplasmic reticulum Expressed in all testis: 87.6 -GJB6 CX30, DFNA3, ED2, EDH, HED ENSG00000121742 Gap junction protein, beta 6, 30kDa 13 20221971-20232395 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014846 Supported Cell Junctions Group enriched 5 bone marrow: 47.6;cerebral cortex: 39.6;esophagus: 150.3;skin: 32.0 tonsil: 12.7 -GJA3 CX46, CZP3 ENSG00000121743 Gap junction protein, alpha 3, 46kDa 13 20138255-20161049 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA014821 Supported Tissue enhanced 0 heart muscle: 4.7;parathyroid gland: 5.8;placenta: 3.5 testis: 2.5 -TBC1D15 DKFZp761D0223, FLJ12085 ENSG00000121749 TBC1 domain family, member 15 12 71839707-71927248 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013388, HPA015592 Supported Supported Mitochondria
Cytosol Expressed in all thyroid gland: 50.8 -ADGRB2 BAI2 ENSG00000121753 Adhesion G protein-coupled receptor B2 1 31727117-31764893 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052612, HPA054617 Supported Centrosome Tissue enriched 14 cerebral cortex: 72.5 adrenal gland: 5.1 -HCRTR1 OX1R ENSG00000121764 Hypocretin (orexin) receptor 1 1 31617686-31632518 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014018 Approved Mixed adrenal gland: 1.2 -ZCCHC17 HSPC251, pNO40, PS1D ENSG00000121766 Zinc finger, CCHC domain containing 17 1 31296982-31364953 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053727 Supported Nuclear speckles Expressed in all testis: 78.5 -FABP3 FABP11, H-FABP, MDGI, O-FABP ENSG00000121769 Fatty acid binding protein 3, muscle and heart 1 31365625-31376850 Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017830, HPA055754 Supported Approved Golgi apparatus Tissue enriched 6 heart muscle: 2838.6 skeletal muscle: 471.3 -KHDRBS1 FLJ34027, p62, Sam68 ENSG00000121774 KH domain containing, RNA binding, signal transduction associated 1 1 32013829-32060850 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005355, HPA051280, HPA056813 Supported Validated Nucleoplasm Expressed in all endometrium: 133.5 -TMEM39B FLJ10315 ENSG00000121775 Transmembrane protein 39B 1 32072031-32102866 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040191, HPA040224 Approved Approved Vesicles Mixed cervix: 9.7 -CCRL2 ACKR5, CKRX, CRAM-A, CRAM-B, HCR ENSG00000121797 Chemokine (C-C motif) receptor-like 2 3 46407163-46412997 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043238 Approved Mixed lung: 17.7 -CCR2 CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R ENSG00000121807 Chemokine (C-C motif) receptor 2 3 46353734-46360928 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB003793 Approved Tissue enhanced 0 appendix: 53.0 spleen: 20.8 -POLR3GL flj32422, MGC3200 ENSG00000121851 Polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like 1 145964702-145978848 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027288 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 58.9 -GHSR ENSG00000121853 Growth hormone secretagogue receptor 3 172445133-172448456 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level No evidence Evidence at protein level CAB012451 Uncertain Not detected adrenal gland: 0.3 -TNFSF10 Apo-2L, CD253, TL2, TRAIL ENSG00000121858 Tumor necrosis factor (ligand) superfamily, member 10 3 172505508-172523507 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054938 Uncertain Approved Microtubules Expressed in all lung: 260.2 -ZNF639 ANC-2H01, ZASC1 ENSG00000121864 Zinc finger protein 639 3 179322991-179338583 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049023, HPA052163 Uncertain Supported Nucleoplasm Expressed in all thyroid gland: 68.7 -SLITRK3 KIAA0848 ENSG00000121871 SLIT and NTRK-like family, member 3 3 165186720-165197109 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA017636 Approved Mitochondria Tissue enhanced 0 cerebral cortex: 17.4;endometrium: 12.4 fallopian tube: 9.7 -PIK3CA PI3K ENSG00000121879 Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 3 179148114-179240093 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009985, CAB017804 Approved Approved Cytosol Mixed parathyroid gland: 23.9 -PDS5A KIAA0648, PIG54, SCC-112 ENSG00000121892 PDS5 cohesin associated factor A 4 39822863-39977956 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036661, HPA036662 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 56.3 -TMEM156 FLJ23235 ENSG00000121895 Transmembrane protein 156 4 38966744-39032922 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 6 appendix: 12.2;lymph node: 28.1;spleen: 15.4;tonsil: 25.3;urinary bladder: 5.9 gallbladder: 3.1 -LIAS LAS ENSG00000121897 Lipoic acid synthetase 4 39459000-39477653 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018842, HPA019076 Approved Approved Approved Nucleoplasm
Mitochondria Expressed in all testis: 31.5 -CPXM2 CPX2, UNQ676 ENSG00000121898 Carboxypeptidase X (M14 family), member 2 10 123706207-123940267 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA048375 Uncertain Tissue enhanced 0 epididymis: 71.4;smooth muscle: 79.7 urinary bladder: 35.5 -TMEM54 CAC-1 ENSG00000121900 Transmembrane protein 54 1 32894594-32901438 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA061992 Approved Vesicles Mixed colon: 226.8 -ZSCAN20 KOX29, ZNF31, ZNF360 ENSG00000121903 Zinc finger and SCAN domain containing 20 1 33472645-33496507 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA017933 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 5.4 -CSMD2 KIAA1884 ENSG00000121904 CUB and Sushi multiple domains 2 1 33513999-34165842 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008622 Uncertain Tissue enhanced 0 cerebral cortex: 2.6;gallbladder: 1.8 testis: 1.0 -HPCA ENSG00000121905 Hippocalcin 1 32885994-32898441 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012340, HPA043245 Supported Tissue enriched 47 cerebral cortex: 153.6 testis: 3.2 -LRIF1 C1orf103, FLJ11269, RIF1 ENSG00000121931 Ligand dependent nuclear receptor interacting factor 1 1 110947185-110964079 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044515 Uncertain Supported Nucleus
Microtubule organizing center Expressed in all testis: 46.7 -TMIGD3 AD026 ENSG00000121933 Transmembrane and immunoglobulin domain containing 3 1 111483348-111563962 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 15 testis: 98.4 placenta: 6.5 -CLCC1 MCLC ENSG00000121940 Chloride channel CLIC-like 1 1 108929508-108963457 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009087, HPA013210 Supported Validated Endoplasmic reticulum Expressed in all parathyroid gland: 38.0 -GPSM2 DFNB82, LGN, Pins ENSG00000121957 G-protein signaling modulator 2 1 108875350-108934545 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007327, HPA008408, CAB018962 Uncertain Supported Cytosol Mixed skin: 49.4 -GTDC1 FLJ11753, Hmat-Xa ENSG00000121964 Glycosyltransferase-like domain containing 1 2 143938068-144332568 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036694 Uncertain Approved Cytosol Expressed in all cerebral cortex: 29.5 -CXCR4 CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R ENSG00000121966 Chemokine (C-X-C motif) receptor 4 2 136114349-136118165 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 772.9 tonsil: 514.7 -ZRANB3 DKFZP434B1727 ENSG00000121988 Zinc finger, RAN-binding domain containing 3 2 135136916-135531236 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035234 Supported Nucleus Mixed testis: 8.5 -ACVR2A ACTRII, ACVR2 ENSG00000121989 Activin A receptor, type IIA 2 147844517-147930826 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046997 Approved Approved Cytosol Mixed skin: 22.5 -POLK DINB1, DINP, POLQ ENSG00000122008 Polymerase (DNA directed) kappa 5 75511756-75601144 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012035, HPA057303, HPA068117, HPA069375 Validated Nucleoplasm
Nuclear bodies Mixed thyroid gland: 12.8 -SV2C ENSG00000122012 Synaptic vesicle glycoprotein 2C 5 76083172-76353939 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA040722, HPA040770 Supported Approved Nucleoplasm
Vesicles Tissue enhanced 0 adrenal gland: 1.7;cerebral cortex: 3.4 ovary: 0.6 -FLT3 CD135, FLK2, STK1 ENSG00000122025 Fms-related tyrosine kinase 3 13 28003274-28100592 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047539 Approved Endoplasmic reticulum Tissue enhanced 0 lymph node: 7.1;spleen: 7.8 appendix: 4.0 -RPL21 DKFZp686C06101, FLJ27458, L21, MGC104274, MGC104275, MGC71252 ENSG00000122026 Ribosomal protein L21 13 27251309-27256691 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047252 Approved Supported Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Expressed in all ovary: 2378.0 -MTIF3 IF-3mt, IF3(mt) ENSG00000122033 Mitochondrial translational initiation factor 3 13 27435643-27450591 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039791 Approved Supported Nucleoplasm
Mitochondria Expressed in all testis: 100.8 -GTF3A AP2, TFIIIA ENSG00000122034 General transcription factor IIIA 13 27424544-27435823 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007990 Supported Supported Nucleus Expressed in all lymph node: 99.6 -RASL11A ENSG00000122035 RAS-like, family 11, member A 13 27270327-27273690 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA004859, HPA053296 Supported Approved Nuclear bodies Mixed rectum: 25.4 -UBL3 DKFZP434K151, FLJ32018, HCG-1, PNSC1 ENSG00000122042 Ubiquitin-like 3 13 29764371-29850684 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053772, HPA058781 Uncertain Approved Centrosome Expressed in all cerebral cortex: 90.9 -FYTTD1 DKFZp761B1514, UIF ENSG00000122068 Forty-two-three domain containing 1 3 197737179-197787596 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054474 Supported Nuclear speckles Expressed in all testis: 76.3 -MTERF4 MGC61716, MTERFD2 ENSG00000122085 Mitochondrial transcription termination factor 4 2 241072169-241102332 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027097 Uncertain Supported Mitochondria
Cytosol Expressed in all thyroid gland: 58.8 -XPNPEP2 ENSG00000122121 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound X 129738974-129769538 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA000339, CAB025136, CAB025269 Supported Approved Golgi apparatus Group enriched 13 duodenum: 131.6;kidney: 174.6;small intestine: 236.2 liver: 14.3 -SASH3 753P9, CXorf9, HACS2, SH3D6C, SLY ENSG00000122122 SAM and SH3 domain containing 3 X 129779979-129795201 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001085 Supported Tissue enhanced 0 lymph node: 138.5;spleen: 100.9;tonsil: 101.1 appendix: 83.1 -OCRL OCRL1 ENSG00000122126 Oculocerebrorenal syndrome of Lowe X 129539849-129592561 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012495 Approved Approved Microtubules
Cytosol Expressed in all parathyroid gland: 64.0 -PAEP GD, GdA, GdF, GdS, MGC138509, MGC142288, PAEG, PEP, PP14 ENSG00000122133 Progestagen-associated endometrial protein 9 135561756-135566955 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016762, HPA020108, HPA029473 Supported Tissue enriched 7 endometrium: 437.4 seminal vesicle: 60.8 -OBP2A hOBPIIa, LCN13, OBP ENSG00000122136 Odorant binding protein 2A 9 135546139-135549969 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055955 Uncertain Group enriched 19 fallopian tube: 35.1;testis: 7.6 skin: 1.1 -MRPS2 CGI-91 ENSG00000122140 Mitochondrial ribosomal protein S2 9 135499984-135504673 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029487, HPA057261 Approved Supported Mitochondria Expressed in all fallopian tube: 54.4 -TBX22 CLPA, CPX ENSG00000122145 T-box 22 X 80014756-80031769 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 18 testis: 10.4;thyroid gland: 3.4 seminal vesicle: 0.3 -FMOD SLRR2E ENSG00000122176 Fibromodulin 1 203340628-203351489 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed gallbladder: 172.3 -MYOG bHLHc3, MYF4 ENSG00000122180 Myogenin (myogenic factor 4) 1 203083132-203086036 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA028336, HPA038093 Approved Supported Nucleoplasm Tissue enriched 12 skeletal muscle: 31.7 prostate: 2.7 -LAX1 FLJ20340, LAX ENSG00000122188 Lymphocyte transmembrane adaptor 1 1 203765176-203776233 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002461, HPA003887, CAB025358 Supported Validated Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 tonsil: 16.0 lymph node: 10.4 -PLG ENSG00000122194 Plasminogen 6 160702238-160753315 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000668, CAB016678, HPA021602, HPA048823, HPA053770 Supported Uncertain Vesicles Tissue enriched 6 liver: 1748.3 kidney: 310.9 -KIAA1191 FLJ21022, p33MONOX ENSG00000122203 KIAA1191 5 176346061-176361968 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044701, HPA048145 Uncertain Approved Nucleoplasm Expressed in all kidney: 197.1 -COPA HEP-COP ENSG00000122218 Coatomer protein complex, subunit alpha 1 160289273-160343400 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028024 Supported Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 116.6 -CD244 2B4, NAIL, NKR2B4, Nmrk, SLAMF4 ENSG00000122223 CD244 molecule, natural killer cell receptor 2B4 1 160830160-160862855 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 spleen: 23.9 bone marrow: 6.3 -LY9 CD229, hly9, mLY9, SLAMF3 ENSG00000122224 Lymphocyte antigen 9 1 160796074-160828261 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050917 Approved Tissue enhanced 0 lymph node: 35.0;spleen: 28.9;tonsil: 29.4 appendix: 18.5 -HS3ST2 3OST2 ENSG00000122254 Heparan sulfate (glucosamine) 3-O-sulfotransferase 2 16 22814177-22916338 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA017736 Approved Tissue enriched 30 cerebral cortex: 35.8 lung: 1.1 -RBBP6 P2P-R, PACT, SNAMA ENSG00000122257 Retinoblastoma binding protein 6 16 24537693-24572863 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032866, HPA041725, HPA043544 Approved Validated Nuclear speckles Expressed in all bone marrow: 91.7 -ZC3H7A FLJ20318, HSPC055, ZC3H7, ZC3HDC7 ENSG00000122299 Zinc finger CCCH-type containing 7A 16 11750586-11797267 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040808, HPA059849 Uncertain Supported Cytosol Expressed in all parathyroid gland: 46.1 -PRM2 CT94.2 ENSG00000122304 Protamine 2 16 11275639-11276480 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032738, HPA056386 Supported Tissue enriched 5039 testis: 7760.1 small intestine: 1.5 -SERAC1 FLJ14917 ENSG00000122335 Serine active site containing 1 6 158109515-158168270 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025715, HPA025716 Approved Expressed in all testis: 16.5 -ANXA11 ANX11 ENSG00000122359 Annexin A11 10 80150889-80205572 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004851, HPA027545 Supported Supported Nucleoplasm
Cytosol Expressed in all esophagus: 203.9 -LDB3 CMD1C, KIAA0613, PDLIM6, ZASP ENSG00000122367 LIM domain binding 3 10 86668449-86736068 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048955 Supported Supported Nucleoplasm
Focal adhesion sites
Cytosol Group enriched 13 heart muscle: 559.4;skeletal muscle: 1040.0 esophagus: 59.4 -OPN4 melanopsin, MOP ENSG00000122375 Opsin 4 10 86654557-86666848 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA039147 Approved Tissue enhanced 0 cerebral cortex: 2.2;parathyroid gland: 1.4 skeletal muscle: 0.9 -FAM35A bA163M19.1, FAM35A1, MGC5560 ENSG00000122376 Family with sequence similarity 35, member A 10 87094161-87191468 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA036582 Uncertain Approved Nucleoplasm
Actin filaments Expressed in all thyroid gland: 38.6 -FAM213A C10orf58, MGC4248, PAMM ENSG00000122378 Family with sequence similarity 213, member A 10 80407829-80437115 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009025, HPA024565 Approved Expressed in all adipose tissue: 424.6 -ZNF205 Zfp13, ZNF210 ENSG00000122386 Zinc finger protein 205 16 3112560-3120517 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA001791 Uncertain Approved Nucleoplasm Expressed in all parathyroid gland: 17.1 -NAA60 FLJ14154, NAT15 ENSG00000122390 N(alpha)-acetyltransferase 60, NatF catalytic subunit 16 3443611-3486963 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA040916 Approved Uncertain Actin filaments
Cytosol Expressed in all parathyroid gland: 84.6 -RPL5 L5, PPP1R135 ENSG00000122406 Ribosomal protein L5 1 92832025-92841924 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043717 Approved Expressed in all ovary: 4031.6 -ODF2L KIAA1229 ENSG00000122417 Outer dense fiber of sperm tails 2-like 1 86346824-86396342 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028020, HPA028095, HPA028333 Uncertain Approved Mitochondria Expressed in all fallopian tube: 34.0 -PTGFR FP ENSG00000122420 Prostaglandin F receptor (FP) 1 78303884-78539749 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 endometrium: 30.3;smooth muscle: 25.4 urinary bladder: 13.3 -TRMT13 CCDC76, FLJ10287, FLJ11219 ENSG00000122435 TRNA methyltransferase 13 homolog (S. cerevisiae) 1 100133150-100150497 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028494 Approved Approved Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Expressed in all parathyroid gland: 28.8 -LRRC39 MGC14816 ENSG00000122477 Leucine rich repeat containing 39 1 100148449-100178273 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028443, HPA029724 Uncertain Group enriched 10 heart muscle: 79.5;skeletal muscle: 175.7 testis: 12.2 -RWDD3 DKFZP566K023 ENSG00000122481 RWD domain containing 3 1 95234155-95247225 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed endometrium: 14.5 -ZNF644 BM-005, KIAA1221, MGC60165, MGC70410 ENSG00000122482 Zinc finger protein 644 1 90915298-91022272 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057795 Uncertain Uncertain Vesicles Expressed in all thyroid gland: 31.0 -CCDC18 NY-SAR-41 ENSG00000122483 Coiled-coil domain containing 18 1 93179919-93278730 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA028035 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 17.2 lymph node: 10.9 -RPAP2 C1orf82, FLJ13150, Rtr1 ENSG00000122484 RNA polymerase II associated protein 2 1 92298965-92402056 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046443 Approved Supported Nucleoli
Cytosol Mixed epididymis: 6.0 -PQLC1 FLJ22378 ENSG00000122490 PQ loop repeat containing 1 18 79902420-79951664 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051666 Uncertain Approved Nucleoplasm Expressed in all adipose tissue: 40.5 -BBS9 B1, PTHB1 ENSG00000122507 Bardet-Biedl syndrome 9 7 33129244-33606068 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021289 Uncertain Mixed testis: 23.8 -PMS2 HNPCC4, H_DJ0042M02.9, MLH4, PMSL2 ENSG00000122512 PMS1 homolog 2, mismatch repair system component 7 5973239-6009125 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010235, HPA044400, HPA066490, HPA070310 Approved Validated Nucleoplasm
Cytosol Mixed cerebral cortex: 20.0 -ZMIZ2 DKFZp761I2123, hZIMP7, KIAA1886, NET27, ZIMP7 ENSG00000122515 Zinc finger, MIZ-type containing 2 7 44748581-44769881 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040716 Supported Supported Nucleoplasm Expressed in all cerebral cortex: 40.9 -OCM OCM1 ENSG00000122543 Oncomodulin 7 5879827-5886362 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046422 Uncertain Tissue enhanced 0 lymph node: 2.5 testis: 1.5 -SEPT7 CDC10, CDC3, SEPT7A ENSG00000122545 Septin 7 7 35800932-35907105 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023309, HPA029524 Supported Approved Actin filaments
Microtubules Expressed in all cerebral cortex: 431.7 -EEPD1 KIAA1706 ENSG00000122547 Endonuclease/exonuclease/phosphatase family domain containing 1 7 36153149-36301543 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053668 Approved Nuclear speckles
Vesicles
Plasma membrane Expressed in all cerebral cortex: 27.2 -KLHL7 KLHL6, RP42, SBBI26 ENSG00000122550 Kelch-like family member 7 7 23105758-23177914 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029491, HPA029492 Uncertain Supported Nucleoplasm
Cytosol Expressed in all testis: 75.7 -HERPUD2 FLJ22313 ENSG00000122557 HERPUD family member 2 7 35632659-35695571 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA015630, HPA076087 Approved Approved Nucleoli Expressed in all testis: 51.6 -CBX3 HP1Hs-gamma ENSG00000122565 Chromobox homolog 3 7 26201162-26213356 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001973, HPA004902 Supported Supported Nucleus
Nuclear bodies Expressed in all testis: 203.5 -HNRNPA2B1 HNRPA2B1 ENSG00000122566 Heterogeneous nuclear ribonucleoprotein A2/B1 7 26189927-26201529 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001666, HPA005812, CAB012403, HPA065537 Supported Validated Nucleoplasm Expressed in all lymph node: 762.7 -WIPF3 CR16, FLJ36931 ENSG00000122574 WAS/WASL interacting protein family, member 3 7 29806486-29917066 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041145, HPA041211 Uncertain Uncertain Mitochondria Tissue enhanced 0 ovary: 52.7;testis: 37.2 epididymis: 24.7 -NXPH1 ENSG00000122584 Neurexophilin 1 7 8433955-8752963 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA020062 Uncertain Group enriched 83 adrenal gland: 52.3;cerebral cortex: 47.3 breast: 0.5 -NPY PYY4 ENSG00000122585 Neuropeptide Y 7 24284163-24291865 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009978, CAB016733, CAB034368, HPA044572, HPA056798 Supported Supported Validated Golgi apparatus Group enriched 16 adrenal gland: 154.2;cerebral cortex: 212.3;prostate: 448.9 appendix: 16.6 -FAM126A DRCTNNB1A , HCC, HYCC1, hyccin ENSG00000122591 Family with sequence similarity 126, member A 7 22889371-23014130 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042873 Approved Supported Plasma membrane
Cytosol Expressed in all testis: 33.2 -HOXA7 HOX1, HOX1A ENSG00000122592 Homeobox A7 7 27153716-27157936 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA074048 Approved Nucleoplasm
Nuclear membrane Mixed epididymis: 22.3 -INHBA ENSG00000122641 Inhibin, beta A 7 41685114-41703108 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020031 Uncertain Tissue enhanced 0 endometrium: 28.7;gallbladder: 35.0 lung: 16.4 -FKBP9 FKBP60, FKBP63 ENSG00000122642 FK506 binding protein 9, 63 kDa 7 32957404-33006931 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012595, HPA055256 Approved Approved Golgi apparatus
Vesicles
Mitochondria Expressed in all placenta: 109.6 -NT5C3A cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1 ENSG00000122643 5'-nucleotidase, cytosolic IIIA 7 33014114-33062797 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010630, HPA029058 Uncertain Expressed in all rectum: 47.0 -ARL4A ARL4 ENSG00000122644 ADP-ribosylation factor-like 4A 7 12686856-12690934 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064513 Supported Nucleoplasm
Cytosol Tissue enhanced 0 testis: 311.7 skin: 79.3 -CCZ1 C7orf28A, CCZ1A, CGI-43 ENSG00000122674 CCZ1 homolog, vacuolar protein trafficking and biogenesis associated 7 5898725-5926550 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045114, HPA050006 Uncertain Validated Vesicles Expressed in all parathyroid gland: 73.7 -POLM Tdt-N ENSG00000122678 Polymerase (DNA directed), mu 7 44072247-44082540 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058900, HPA066007 Supported Nucleus Expressed in all spleen: 11.1 -RAMP3 ENSG00000122679 Receptor (G protein-coupled) activity modifying protein 3 7 45157791-45186302 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lung: 120.5 thyroid gland: 66.2 -FTSJ2 FJH1, MRM2, RRMJ2 ENSG00000122687 FtsJ RNA methyltransferase homolog 2 (E. coli) 7 2234231-2242198 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019826, HPA049622 Uncertain Expressed in all lymph node: 19.9 -TWIST1 ACS3, bHLHa38, BPES2, BPES3, CRS, CRS1, H-twist, SCS, TWIST ENSG00000122691 Twist family bHLH transcription factor 1 7 19020991-19117672 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adipose tissue: 22.7;endometrium: 30.7 placenta: 17.2 -SMU1 BWD, FLJ10805, fSAP57, SMU-1 ENSG00000122692 Smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 9 33041764-33076659 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019228, HPA019708 Supported Approved Vesicles Expressed in all parathyroid gland: 27.1 -GLIPR2 C9orf19, GAPR-1 ENSG00000122694 GLI pathogenesis-related 2 9 36136536-36163913 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029478 Approved Uncertain Vesicles
Microtubules Expressed in all lung: 93.8 -SLC25A51 CG7943, MCART1, MGC14836 ENSG00000122696 Solute carrier family 25, member 51 9 37879400-37904353 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046388, HPA058261 Uncertain Approved Mitochondria Expressed in all parathyroid gland: 16.4 -CLTA Lca ENSG00000122705 Clathrin, light chain A 9 36190856-36304781 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002665, HPA050918, HPA054667 Supported Supported Endosomes
Lysosomes Expressed in all placenta: 176.8 -RECK hRECK, ST15 ENSG00000122707 Reversion-inducing-cysteine-rich protein with kazal motifs 9 36036433-36124451 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025109, HPA071729 Supported Supported Plasma membrane Mixed endometrium: 21.3 -SPINK4 MGC133107, PEC-60 ENSG00000122711 Serine peptidase inhibitor, Kazal type 4 9 33218365-33248567 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA007286 Supported Approved Nucleus
Golgi apparatus
Vesicles Group enriched 6 colon: 647.7;duodenum: 273.9;rectum: 1085.3;small intestine: 748.6 appendix: 112.0 -OR2S2 ENSG00000122718 Olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) 9 35957139-35958098 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected lung: 0.1 -TAF1L ENSG00000122728 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 9 32629454-32635669 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056605 Uncertain Tissue enriched 31 testis: 3.0 epididymis: 0.0 -ACO1 IREB1, IREBP, IRP1 ENSG00000122729 Aconitase 1, soluble 9 32384603-32454769 Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019371, HPA024157 Supported Supported Mitochondria
Cytosol Expressed in all adipose tissue: 104.8 -PHF24 KIAA1045 ENSG00000122733 PHD finger protein 24 9 34957608-34982544 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020974 Approved Group enriched 36 cerebral cortex: 58.7;testis: 25.8 skin: 1.1 -DNAI1 CILD1, DIC1, PCD ENSG00000122735 Dynein, axonemal, intermediate chain 1 9 34457414-34520989 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021649, HPA021843 Approved Group enriched 10 fallopian tube: 53.6;testis: 60.9 lung: 5.6 -DCAF10 FLJ23201, MGC10765, WDR32 ENSG00000122741 DDB1 and CUL4 associated factor 10 9 37800502-37867666 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024160 Uncertain Approved Nucleoli fibrillar center Expressed in all testis: 35.7 -CNTFR ENSG00000122756 Ciliary neurotrophic factor receptor 9 34551432-34590140 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025310, HPA036635 Approved Approved Golgi apparatus Tissue enhanced 0 adipose tissue: 62.5;cerebral cortex: 53.6 spleen: 28.0 -KIAA1549 ENSG00000122778 KIAA1549 7 138831381-138981318 Cancer-related genes, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019560 Approved Approved Nuclear membrane
Intermediate filaments Mixed seminal vesicle: 10.4 -TRIM24 hTIF1, RNF82, TIF1, Tif1a ENSG00000122779 Tripartite motif containing 24 7 138460334-138589993 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043495, HPA061717 Approved Validated Nucleoplasm Expressed in all testis: 49.5 -C7orf49 FLJ22450, FLJ27285, MGC5242, MRI ENSG00000122783 Chromosome 7 open reading frame 49 7 135092363-135170795 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA020060 Approved Approved Golgi apparatus Expressed in all parathyroid gland: 37.8 -CALD1 CDM, H-CAD, L-CAD ENSG00000122786 Caldesmon 1 7 134744252-134970728 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000006, HPA008066, HPA017330 Supported Validated Plasma membrane
Actin filaments Tissue enhanced 0 seminal vesicle: 1285.3 smooth muscle: 1186.8 -AKR1D1 SRD5B1 ENSG00000122787 Aldo-keto reductase family 1, member D1 7 138002324-138117986 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057002 Supported Approved Nucleoplasm
Cytosol Tissue enriched 32 liver: 229.0 breast: 7.1 -NUDT10 DIPP3a, hDIPP3alpha ENSG00000122824 Nudix (nucleoside diphosphate linked moiety X)-type motif 10 X 51332231-51337525 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047027, HPA057684 Approved Approved Cytosol Tissue enhanced 0 testis: 49.6 prostate: 24.3 -SFTPA1 COLEC4, SFTP1, SP-A, SP-A1 ENSG00000122852 Surfactant protein A1 10 79610939-79615455 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB016793, HPA042638, HPA045752, HPA049368 Supported Tissue enriched 1177 lung: 10520.7 adrenal gland: 8.9 -NEUROG3 Atoh5, bHLHa7, Math4B, ngn3 ENSG00000122859 Neurogenin 3 10 69571698-69573238 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA039785 Uncertain Tissue enhanced 0 duodenum: 2.9;small intestine: 1.3 rectum: 0.4 -PLAU UPA, URK ENSG00000122861 Plasminogen activator, urokinase 10 73909177-73917497 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008719 Approved Approved Plasma membrane
Cytosol Expressed in all appendix: 61.3 -SRGN PPG, PRG, PRG1 ENSG00000122862 Serglycin 10 69088106-69104811 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000759 Supported Group enriched 6 appendix: 1146.8;bone marrow: 5150.0 gallbladder: 510.5 -CHST3 C6ST, C6ST1 ENSG00000122863 Carbohydrate (chondroitin 6) sulfotransferase 3 10 71964365-72013564 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047523, HPA055704 Approved Approved Golgi apparatus
Cytosol Mixed testis: 30.7 -BICC1 ENSG00000122870 BicC family RNA binding protein 1 10 58513140-58831437 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045212 Approved Approved Nucleoplasm Mixed kidney: 31.8 -CISD1 C10orf70, MDS029, mitoNEET, ZCD1 ENSG00000122873 CDGSH iron sulfur domain 1 10 58269058-58289586 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045965, HPA074383 Uncertain Supported Mitochondria Tissue enhanced 0 parathyroid gland: 116.1 cerebral cortex: 27.3 -EGR2 KROX20 ENSG00000122877 Early growth response 2 10 62811996-62919900 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA031165 Supported Nucleoplasm Tissue enhanced 0 epididymis: 97.2;thyroid gland: 215.5 gallbladder: 46.3 -ECD GCR2, hSGT1 ENSG00000122882 Ecdysoneless homolog (Drosophila) 10 73130155-73169055 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006465 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 40.1 -P4HA1 C-P4Halpha(I), P4HA ENSG00000122884 Prolyl 4-hydroxylase, alpha polypeptide I 10 73007217-73096974 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007599, HPA026593 Supported Supported Endoplasmic reticulum
Vesicles
Mitochondria Expressed in all placenta: 91.1 -SLC25A16 D10S105E, GDA, HGT.1, ML7 ENSG00000122912 Solute carrier family 25 (mitochondrial carrier), member 16 10 68477999-68527474 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036243, HPA044580 Uncertain Approved Mitochondria Mixed prostate: 13.7 -ZWINT KNTC2AP, SIP30 ENSG00000122952 ZW10 interacting kinetochore protein 10 56357228-56361275 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005757, HPA022264, CAB033926 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Mixed testis: 47.5 -VPS26A Hbeta58, PEP8A, VPS26 ENSG00000122958 VPS26 retromer complex component A 10 69123512-69172861 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011602, HPA057498, CAB075733 Supported Validated Endosomes
Lysosomes Expressed in all testis: 86.5 -RBM19 DKFZp586F1023, KIAA0682 ENSG00000122965 RNA binding motif protein 19 12 113816738-113966371 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038860, HPA058732 Supported Supported Nucleoli Expressed in all parathyroid gland: 19.3 -CIT CRIK, KIAA0949, STK21 ENSG00000122966 Citron rho-interacting serine/threonine kinase 12 119685790-119877291 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019082, HPA048812, HPA075506 Uncertain Approved Cytosol Mixed cerebral cortex: 10.4 -IFT81 CDV-1R, CDV1, MGC4027 ENSG00000122970 Intraflagellar transport 81 12 110124335-110218797 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019087, HPA020051 Supported Approved Centrosome
Cytosol Mixed testis: 57.7 -ACADS ACAD3, SCAD ENSG00000122971 Acyl-CoA dehydrogenase, C-2 to C-3 short chain 12 120725735-120740008 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004799, CAB019284, HPA022271 Supported Supported Nucleoplasm
Mitochondria Expressed in all duodenum: 83.5 -HVCN1 Hv1, MGC15619, VSOP ENSG00000122986 Hydrogen voltage gated channel 1 12 110627841-110704950 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039329 Approved Mixed testis: 82.3 -DDX54 APR-5, DP97, MGC2835 ENSG00000123064 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 12 113157174-113185479 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028244, HPA070786 Approved Approved Nucleus
Nucleoli
Golgi apparatus Expressed in all appendix: 40.2 -MED13L KIAA1025, THRAP2, TRAP240L ENSG00000123066 Mediator complex subunit 13-like 12 115953872-116277338 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039445 Uncertain Approved Nucleus
Golgi apparatus Expressed in all bone marrow: 36.0 -CDKN2C INK4C, p18 ENSG00000123080 Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1 50960745-50974633 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB005303, CAB018398, HPA019057, HPA019764 Approved Approved Nucleoplasm
Cytosol Expressed in all adipose tissue: 80.3 -RNF11 CGI-123, MGC51169, Sid1669p ENSG00000123091 Ring finger protein 11 1 51236271-51273455 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045781 Uncertain Expressed in all cerebral cortex: 151.9 -RASSF8 C12orf2, HoJ-1 ENSG00000123094 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 12 25959029-26079892 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038163, HPA038164 Uncertain Approved Mitochondria
Cytosol Tissue enhanced 0 testis: 105.8 endometrium: 46.9 -BHLHE41 BHLHB3, bHLHe41, DEC2, SHARP-1, SHARP1 ENSG00000123095 Basic helix-loop-helix family, member e41 12 26120026-26125127 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056035 Approved Nucleoplasm Tissue enhanced 0 thyroid gland: 94.0 fallopian tube: 70.3 -SSPN KRAG, SPN1, SPN2 ENSG00000123096 Sarcospan 12 26121991-26299290 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA066432 Approved Nucleus
Nuclear membrane Mixed cervix: 64.1 -ITPR2 CFAP48, IP3R2 ENSG00000123104 Inositol 1,4,5-trisphosphate receptor, type 2 12 26336515-26833198 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059144, HPA062260 Uncertain Supported Nucleus
Endoplasmic reticulum Mixed parathyroid gland: 25.7 -CCDC91 DKFZp779L1558, FLJ11088, p56 ENSG00000123106 Coiled-coil domain containing 91 12 28133249-28581511 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038169 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 43.0 -NECAB1 EFCBP1 ENSG00000123119 N-terminal EF-hand calcium binding protein 1 8 90791550-90959408 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023252, HPA023629, HPA025963, HPA031262, CAB068208, CAB068209, CAB068210 Supported Supported Supported Nucleoplasm
Cytosol Tissue enriched 7 cerebral cortex: 79.9 testis: 12.2 -WWP1 AIP5, DKFZP434D2111 ENSG00000123124 WW domain containing E3 ubiquitin protein ligase 1 8 86342738-86478420 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023180 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Expressed in all parathyroid gland: 185.9 -ACOT9 ACATE2, CGI-16, MT-ACT48 ENSG00000123130 Acyl-CoA thioesterase 9 X 23702253-23766475 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035533 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all smooth muscle: 46.3 -PRDX4 AOE37-2 ENSG00000123131 Peroxiredoxin 4 X 23664262-23686399 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008659, CAB027389, CAB047362 Supported Supported Endoplasmic reticulum
Cytosol Expressed in all pancreas: 239.4 -DDX39A BAT1L, DDX39, DDXL, URH49 ENSG00000123136 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 19 14408819-14419383 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055334 Approved Approved Nuclear speckles Expressed in all testis: 209.6 -PKN1 DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1 ENSG00000123143 Protein kinase N1 19 14433053-14471867 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003982, CAB010278 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all spleen: 87.5 -C19orf43 fSAP18, MGC2803 ENSG00000123144 Chromosome 19 open reading frame 43 19 12730640-12734775 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059965 Approved Approved Nucleoplasm Expressed in all spleen: 127.8 -ADGRE5 CD97, TM7LN1 ENSG00000123146 Adhesion G protein-coupled receptor E5 19 14380501-14408725 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013707 Supported Approved Cytosol Expressed in all spleen: 142.8 -WDR83 MORG1 ENSG00000123154 WD repeat domain 83 19 12666800-12675832 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042629, HPA042838 Uncertain Approved Nucleoplasm
Vesicles
Centrosome Mixed testis: 9.3 -GIPC1 C19orf3, GIPC, GLUT1CBP, Hs.6454, NIP, RGS19IP1, SEMCAP, SYNECTIN, TIP-2 ENSG00000123159 GIPC PDZ domain containing family, member 1 19 14477760-14496149 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043958, HPA061786 Approved Approved Nucleus
Plasma membrane
Cell Junctions Expressed in all esophagus: 104.4 -ACTRT1 AIP1, ARIP1, Arp-T1, KIAA0705 ENSG00000123165 Actin-related protein T1 X 128050962-128052398 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA003119 Supported Tissue enriched 36 testis: 3.6 epididymis: 0.0 -CCDC70 DKFZP434K1172, FLJ25853 ENSG00000123171 Coiled-coil domain containing 70 13 51861981-51866232 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 1154 testis: 115.3 epididymis: 0.0 -SPRYD7 C13orf1, CLLD6 ENSG00000123178 SPRY domain containing 7 13 49912706-49936490 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043934 Approved Approved Vesicles Expressed in all cerebral cortex: 18.8 -EBPL EBRP ENSG00000123179 Emopamil binding protein-like 13 49660723-49691475 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049891 Approved Supported Endoplasmic reticulum Expressed in all liver: 61.3 -ATP7B WND ENSG00000123191 ATPase, Cu++ transporting, beta polypeptide 13 51930436-52012125 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009137, HPA013187 Supported Supported Golgi apparatus Mixed testis: 14.0 -ZC3H13 DKFZp434D1812, KIAA0853 ENSG00000123200 Zinc finger CCCH-type containing 13 13 45954465-46052759 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039340, HPA040140, HPA047806 Uncertain Approved Nuclear membrane
Actin filaments Expressed in all cerebral cortex: 33.6 -NLN AGTBP, KIAA1226 ENSG00000123213 Neurolysin (metallopeptidase M3 family) 5 65722196-65871725 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031862 Approved Approved Mitochondria Mixed cerebral cortex: 8.3 -CENPK CENP-K, FKSG14, SOLT ENSG00000123219 Centromere protein K 5 65517766-65563171 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed testis: 24.7 -OPTN FIP-2, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP ENSG00000123240 Optineurin 10 13099449-13138308 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003279, HPA003360, CAB019303 Supported Validated Cytosol Expressed in all skeletal muscle: 300.2 -ITIH5 MGC10848 ENSG00000123243 Inter-alpha-trypsin inhibitor heavy chain family, member 5 10 7559270-7666998 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038305 Approved Approved Golgi apparatus
Vesicles Mixed placenta: 122.7 -ATF1 TREB36 ENSG00000123268 Activating transcription factor 1 12 50763710-50821122 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016222, HPA055069, HPA055406 Supported Validated Nucleoplasm Expressed in all thyroid gland: 39.5 -TSFM EF-TS, EF-Tsmt ENSG00000123297 Ts translation elongation factor, mitochondrial 12 57782589-57808071 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006204 Supported Nucleus
Mitochondria Expressed in all adrenal gland: 64.0 -NEUROD4 ATH-3, Atoh3, bHLHa4, MATH-3 ENSG00000123307 Neuronal differentiation 4 12 55019945-55030014 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA015545 Supported Tissue enhanced 0 adrenal gland: 2.3;testis: 1.0 cerebral cortex: 0.4 -ARHGAP9 10C, MGC1295 ENSG00000123329 Rho GTPase activating protein 9 12 57472255-57488814 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 78.2 lymph node: 69.5 -NCKAP1L HEM1 ENSG00000123338 NCK-associated protein 1-like 12 54497711-54548238 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039490, HPA040772 Approved Uncertain Plasma membrane
Cytosol Mixed spleen: 55.8 -MMP19 MMP18, RASI-1 ENSG00000123342 Matrix metallopeptidase 19 12 55835433-55842966 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070804 Approved Endoplasmic reticulum
Vesicles Tissue enhanced 0 adipose tissue: 63.1;gallbladder: 97.5 placenta: 27.9 -PFDN5 MM-1, PFD5 ENSG00000123349 Prefoldin subunit 5 12 53295291-53299450 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008587 Approved Expressed in all epididymis: 1060.5 -SPATS2 FLJ13117, SCR59, SPATA10 ENSG00000123352 Spermatogenesis associated, serine-rich 2 12 49366584-49527424 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038642, HPA038643, HPA066105 Uncertain Validated Cytosol Expressed in all testis: 49.5 -ORMDL2 adoplin-2, HSPC160, MST095, MSTP095 ENSG00000123353 ORMDL sphingolipid biosynthesis regulator 2 12 55817919-55821879 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065643 Supported Endoplasmic reticulum Expressed in all epididymis: 62.1 -NR4A1 GFRP1, HMR, N10, NAK-1, NGFIB, NUR77, TR3 ENSG00000123358 Nuclear receptor subfamily 4, group A, member 1 12 52022832-52059507 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059742 Supported Nucleus
Cytosol Expressed in all adrenal gland: 753.5 -PDE1B PDES1B ENSG00000123360 Phosphodiesterase 1B, calmodulin-dependent 12 54549350-54579239 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018492 Approved Approved Nucleus
Cytosol Tissue enhanced 0 cerebral cortex: 18.5 parathyroid gland: 11.9 -HOXC13 HOX3, HOX3G ENSG00000123364 Homeobox C13 12 53938765-53946544 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051634 Supported Tissue enriched 7 skin: 4.6 breast: 0.6 -CDK2 ENSG00000123374 Cyclin-dependent kinase 2 12 55966769-55972784 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013115, HPA066915 Supported Validated Nucleoplasm
Centrosome
Cytosol Expressed in all placenta: 65.0 -LRP1 A2MR, APOER, APR, CD91, LRP, LRP1A ENSG00000123384 Low density lipoprotein receptor-related protein 1 12 57128493-57213351 Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004182, CAB018621, HPA022903 Supported Supported Nucleoli
Cytosol Expressed in all adipose tissue: 123.2 -HOXC11 HOX3H ENSG00000123388 Homeobox C11 12 53973126-53977643 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA038291 Uncertain Supported Nucleoplasm
Cytosol Tissue enhanced 0 skin: 2.3 testis: 1.2 -ATG101 C12orf44, FLJ11773 ENSG00000123395 Autophagy related 101 12 52069246-52077494 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039904 Approved Expressed in all gallbladder: 43.8 -NFE2 NF-E2 ENSG00000123405 Nuclear factor, erythroid 2 12 54292111-54301121 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001914 Approved Tissue enriched 6 bone marrow: 68.7 spleen: 12.1 -HOXC12 HOC3F, HOX3, HOX3F ENSG00000123407 Homeobox C12 12 53954834-53958956 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA055632 Uncertain Not detected skin: 0.7 -IKZF4 Eos, ZNFN1A4 ENSG00000123411 IKAROS family zinc finger 4 (Eos) 12 56007659-56038435 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046270, HPA049016 Approved Supported Nucleoplasm
Nuclear bodies Mixed parathyroid gland: 16.1 -SMUG1 FDG, HMUDG, UNG3 ENSG00000123415 Single-strand-selective monofunctional uracil-DNA glycosylase 1 12 54121277-54189008 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051149, HPA071486 Approved Vesicles
Centrosome Expressed in all epididymis: 47.9 -TUBA1B K-ALPHA-1 ENSG00000123416 Tubulin, alpha 1b 12 49127782-49131397 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB011513, HPA039247, HPA043684, HPA063394 Supported Supported Microtubules Expressed in all cerebral cortex: 1417.8 -METTL21B DKFZP586D0919, FAM119B ENSG00000123427 Methyltransferase like 21B 12 57771492-57782798 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043020 Uncertain Approved Nucleoplasm Expressed in all thyroid gland: 17.0 -KBTBD4 BKLHD4, FLJ10450, HSPC252 ENSG00000123444 Kelch repeat and BTB (POZ) domain containing 4 11 47572197-47579015 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037792, HPA037793 Uncertain Approved Nucleus
Vesicles
Cytosol Expressed in all parathyroid gland: 48.0 -SARDH DMGDHL1, SDH ENSG00000123453 Sarcosine dehydrogenase 9 133663560-133739955 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057267, HPA058086 Supported Approved Mitochondria Tissue enhanced 0 epididymis: 58.4;liver: 43.2 kidney: 12.5 -DBH DBM ENSG00000123454 Dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9 133636360-133659344 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002130, HPA005960, HPA070789 Supported Supported Vesicles Tissue enriched 12 adrenal gland: 358.5 epididymis: 30.6 -ATPAF1 ATP11, Atp11p, FLJ22351 ENSG00000123472 ATP synthase mitochondrial F1 complex assembly factor 1 1 46632737-46673867 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028382, HPA044950 Approved Approved Mitochondria Expressed in all parathyroid gland: 172.7 -STIL MCPH7, SIL ENSG00000123473 SCL/TAL1 interrupting locus 1 47250139-47314147 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046543 Approved Plasma membrane
Cytosol Mixed testis: 12.5 -HJURP DKFZp762E1312, FAKTS, hFLEG1, URLC9 ENSG00000123485 Holliday junction recognition protein 2 233833416-233854566 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008436, HPA027261 Uncertain Validated Nucleus
Nucleoli
Cytosol Tissue enhanced 0 bone marrow: 28.7;testis: 19.9 lymph node: 15.3 -IL13RA2 CD213a2, CT19, IL-13R, IL13BP ENSG00000123496 Interleukin 13 receptor, alpha 2 X 115003975-115019977 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055552 Approved Nucleus
Nucleoli Tissue enriched 8 testis: 52.5 prostate: 6.5 -COL10A1 ENSG00000123500 Collagen, type X, alpha 1 6 116118923-116158747 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 gallbladder: 14.6 ovary: 4.9 -AMD1 SAMDC ENSG00000123505 Adenosylmethionine decarboxylase 1 6 110814621-110895713 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029281, HPA029282 Approved Approved Nucleoplasm Expressed in all prostate: 345.5 -NDUFAF4 bA22L21.1, C6orf66, HRPAP20, HSPC125, My013 ENSG00000123545 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 6 96889313-96897881 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046560 Uncertain Supported Mitochondria Expressed in all cerebral cortex: 29.1 -USP45 MGC14793 ENSG00000123552 Ubiquitin specific peptidase 45 6 99432379-99521728 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029602, HPA029604 Uncertain Approved Nucleus
Cytosol Mixed gallbladder: 14.0 -PLP1 GPM6C, PLP, SPG2 ENSG00000123560 Proteolipid protein 1 X 103773718-103792619 Cancer-related genes, Disease related genes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004128 Supported Tissue enriched 30 cerebral cortex: 3225.1 parathyroid gland: 106.1 -SERPINA7 TBG ENSG00000123561 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 X 106032442-106038738 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002803 Approved Tissue enriched 282 liver: 215.5 small intestine: 0.7 -MORF4L2 KIAA0026, MRGX ENSG00000123562 Mortality factor 4 like 2 X 103675496-103688158 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031872, HPA054102 Supported Validated Nucleus Expressed in all smooth muscle: 488.6 -H2BFWT ENSG00000123569 H2B histone family, member W, testis-specific X 104011147-104013687 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA056289 Uncertain Not detected testis: 0.6 -RAB9B RAB9L ENSG00000123570 RAB9B, member RAS oncogene family X 103822322-103832228 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061932 Approved Mixed cerebral cortex: 14.3 -NRK DKFZp686A17109 ENSG00000123572 Nik related kinase X 105822543-105958610 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017238 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 ovary: 39.6;placenta: 34.0 adrenal gland: 21.0 -FAM199X CXorf39 ENSG00000123575 Family with sequence similarity 199, X-linked X 104166620-104195902 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003093 Approved Approved Nucleus
Golgi apparatus
Cytosol Expressed in all epididymis: 42.7 -ESX1 ESX1L, ESXR1 ENSG00000123576 ESX homeobox 1 X 104250038-104254933 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA051992 Supported Supported Nuclear speckles Tissue enriched 64 testis: 12.0 placenta: 0.1 -MAGEA9 CT1.9, MAGE9, MGC8421 ENSG00000123584 Melanoma antigen family A9 X 149781930-149787737 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045401 Approved Golgi apparatus Not detected testis: 0.6 -ATXN3L MJDL ENSG00000123594 Ataxin 3-like X 13318236-13319952 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA024123, HPA027539 Uncertain Tissue enriched 32 testis: 6.1 placenta: 0.1 -RAB9A RAB9 ENSG00000123595 RAB9A, member RAS oncogene family X 13689121-13710506 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003094, CAB016411 Supported Uncertain Nucleoplasm
Cytosol Expressed in all adrenal gland: 63.9 -METTL8 FLJ13984, TIP ENSG00000123600 Methyltransferase like 8 2 171317405-171434802 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035421 Uncertain Approved Cytosol Mixed esophagus: 9.5 -TTC21B FLJ11457, IFT139B, JBTS11, NPHP12, THM1 ENSG00000123607 Tetratricopeptide repeat domain 21B 2 165857475-165953843 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035494, HPA035495 Uncertain Supported Mitochondria Expressed in all fallopian tube: 14.3 -NMI ENSG00000123609 N-myc (and STAT) interactor 2 151270465-151290057 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008588 Approved Supported Nucleoplasm
Cytosol Expressed in all spleen: 47.7 -TNFAIP6 TSG-6, TSG6 ENSG00000123610 Tumor necrosis factor, alpha-induced protein 6 2 151357592-151380048 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032719, HPA050884 Approved Tissue enhanced 0 appendix: 39.5;gallbladder: 31.9 urinary bladder: 18.9 -ACVR1C ACVRLK7, ALK7 ENSG00000123612 Activin A receptor, type IC 2 157526767-157629005 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA007982, HPA011933 Approved Tissue enriched 8 adipose tissue: 33.9 ovary: 4.3 -BAZ2B WALp4 ENSG00000123636 Bromodomain adjacent to zinc finger domain, 2B 2 159318979-159616692 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019819, HPA059292 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 55.7 -SLC36A1 LYAAT-1, PAT1, TRAMD3 ENSG00000123643 Solute carrier family 36 (proton/amino acid symporter), member 1 5 151437046-151492381 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035937 Approved Tissue enhanced 0 parathyroid gland: 64.1 duodenum: 45.5 -LPGAT1 FAM34A, FAM34A1, KIAA0205, NET8 ENSG00000123684 Lysophosphatidylglycerol acyltransferase 1 1 211743457-211830772 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008304 Approved Expressed in all thyroid gland: 43.0 -BATF3 JDP1, JUNDM1, SNFT ENSG00000123685 Basic leucine zipper transcription factor, ATF-like 3 1 212686418-212699985 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed spleen: 4.7 -G0S2 ENSG00000123689 G0/G1 switch 2 1 209675420-209676388 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 adipose tissue: 956.4;bone marrow: 939.4;skeletal muscle: 240.6 appendix: 140.8 -KCNJ2 IRK1, Kir2.1, LQT7 ENSG00000123700 Potassium channel, inwardly rectifying subfamily J, member 2 17 70168673-70180048 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA029109 Approved Tissue enhanced 0 parathyroid gland: 46.5 fallopian tube: 11.6 -RAP2C DKFZp313B211 ENSG00000123728 RAP2C, member of RAS oncogene family X 132203024-132219480 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all endometrium: 101.9 -EXOSC9 p5, p6, PM/Scl-75, PMSCL1, RRP45, Rrp45p ENSG00000123737 Exosome component 9 4 121801317-121817021 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041838, HPA048257, CAB070171 Approved Validated Nucleus
Nucleoli Expressed in all testis: 89.9 -PLA2G12A PLA2G12 ENSG00000123739 Phospholipase A2, group XIIA 4 109709989-109730077 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035908, HPA035909 Approved Expressed in all parathyroid gland: 33.6 -B9D2 MGC4093, MKS10 ENSG00000123810 B9 protein domain 2 19 41354421-41364173 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042229, HPA042618 Approved Mixed fallopian tube: 16.8 -ADCK4 COQ8, FLJ12229 ENSG00000123815 AarF domain containing kinase 4 19 40691529-40718207 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027229, HPA027277, HPA027279, HPA028303 Supported Validated Mitochondria Expressed in all fallopian tube: 40.7 -PFKFB2 ENSG00000123836 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 207034366-207081024 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049975, HPA063575 Uncertain Validated Nucleus Expressed in all thyroid gland: 85.9 -C4BPA C4BP ENSG00000123838 Complement component 4 binding protein, alpha 1 207104262-207144972 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000926, HPA001578 Supported Group enriched 64 liver: 994.5;lung: 261.8 cervix: 9.7 -C4BPB C4BP ENSG00000123843 Complement component 4 binding protein, beta 1 207088842-207099993 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051620 Approved Group enriched 17 liver: 240.3;ovary: 51.9 placenta: 8.7 -RAB38 NY-MEL-1 ENSG00000123892 RAB38, member RAS oncogene family 11 88113242-88175467 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071701 Uncertain Nuclear bodies
Mitochondria Tissue enhanced 0 skin: 47.5 esophagus: 36.4 -GPR83 GPR72 ENSG00000123901 G protein-coupled receptor 83 11 94377311-94401419 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 5 adrenal gland: 1.0;cerebral cortex: 4.6;thyroid gland: 5.2 epididymis: 0.6 -AGO2 EIF2C2, hAGO2, Q10 ENSG00000123908 Argonaute RISC catalytic component 2 8 140520156-140635619 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019309, HPA058075 Approved Supported Nucleoplasm
Cell Junctions Expressed in all parathyroid gland: 11.9 -MXD4 bHLHc12, MAD4, MST149, MSTP149 ENSG00000123933 MAX dimerization protein 4 4 2247432-2262294 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA053363 Supported Cytosol Expressed in all spleen: 42.0 -CKS2 ENSG00000123975 CDC28 protein kinase regulatory subunit 2 9 89311198-89316703 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003424, HPA030762 Approved Supported Approved Nucleus
Vesicles
Mitochondria
Cytosol Tissue enhanced 0 testis: 339.8 lymph node: 124.3 -DAW1 FLJ25955, ODA16, WDR69 ENSG00000123977 Dynein assembly factor with WDR repeat domains 1 2 227871054-227924344 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046118 Approved Approved Nucleoplasm
Nuclear bodies Group enriched 14 fallopian tube: 50.8;testis: 91.6 lung: 5.0 -ACSL3 ACS3, FACL3, PRO2194 ENSG00000123983 Acyl-CoA synthetase long-chain family member 3 2 222860934-222944639 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011315, HPA071021 Uncertain Approved Nucleoli
Lipid droplets Expressed in all parathyroid gland: 670.1 -CHPF CHSY2, CSS2 ENSG00000123989 Chondroitin polymerizing factor 2 219538947-219543787 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035123 Approved Supported Vesicles
Centrosome
Cytosol Expressed in all testis: 77.4 -DNPEP ASPEP, DAP ENSG00000123992 Aspartyl aminopeptidase 2 219373546-219400022 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036398, HPA044860 Supported Supported Cytosol Expressed in all testis: 65.8 -INHA ENSG00000123999 Inhibin, alpha 2 219569162-219575713 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000047, HPA019141 Supported Approved Vesicles Tissue enhanced 0 adrenal gland: 51.8;ovary: 37.9;testis: 106.5 placenta: 14.8 -MOGAT1 DGAT2L, DGAT2L1, MGAT1 ENSG00000124003 Monoacylglycerol O-acyltransferase 1 2 222671786-222709930 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049944 Uncertain Tissue enriched 11 gallbladder: 30.8 parathyroid gland: 2.8 -OBSL1 KIAA0657 ENSG00000124006 Obscurin-like 1 2 219550729-219571859 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036404, HPA036405 Approved Approved Centrosome Expressed in all ovary: 220.2 -FAM124B FLJ22746 ENSG00000124019 Family with sequence similarity 124B 2 224378698-224402085 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA070240 Approved Approved Nucleoplasm Tissue enhanced 0 parathyroid gland: 10.1;placenta: 12.4 lung: 3.7 -SLC12A4 KCC1 ENSG00000124067 Solute carrier family 12 (potassium/chloride transporter), member 4 16 67943474-67969601 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041138 Approved Approved Endosomes Expressed in all parathyroid gland: 62.5 -ENKD1 C16orf48, DKFZP434A1319 ENSG00000124074 Enkurin domain containing 1 16 67662945-67667265 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041163, HPA041478 Approved Supported Plasma membrane
Centrosome
Cytosol Expressed in all parathyroid gland: 32.0 -MC3R MC3 ENSG00000124089 Melanocortin 3 receptor 20 56248732-56249815 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.1 -GCNT7 C20orf105, dJ1153D9.2 ENSG00000124091 Glucosaminyl (N-acetyl) transferase family member 7 20 56491492-56525925 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA052617 Uncertain Tissue enriched 5 bone marrow: 2.8 testis: 0.5 -CTCFL BORIS, CT27, dJ579F20.2 ENSG00000124092 CCCTC-binding factor (zinc finger protein)-like 20 57495966-57525652 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA001472 Supported Tissue enriched 19 testis: 20.6 epididymis: 1.1 -FAM210B C20orf108, dJ1167H4.1, DKFZP434A1114 ENSG00000124098 Family with sequence similarity 210, member B 20 56358915-56368663 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042652 Approved Approved Plasma membrane
Cytosol Expressed in all ovary: 131.1 -PI3 cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14 ENSG00000124102 Peptidase inhibitor 3, skin-derived 20 45174876-45176544 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009449, HPA017737 Supported Approved Plasma membrane Group enriched 15 esophagus: 2295.1;tonsil: 1810.6 appendix: 136.9 -FAM209A C20orf106, dJ1153D9.3 ENSG00000124103 Family with sequence similarity 209, member A 20 56517187-56526142 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 10 testis: 100.2 bone marrow: 9.7 -SNX21 C20orf161, dJ337O18.4, SNX-L ENSG00000124104 Sorting nexin family member 21 20 45833810-45843275 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046359 Approved Approved Vesicles
Microtubule organizing center Mixed skin: 25.3 -SLPI ALK1, ALP, BLPI, HUSI, HUSI-I, WAP4, WFDC4 ENSG00000124107 Secretory leukocyte peptidase inhibitor 20 45252239-45254564 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002303, HPA027774 Supported Approved Golgi apparatus Tissue enriched 10 cervix, uterine: 40728.5 seminal vesicle: 4274.8 -WFDC3 dJ447F3.3, WAP14 ENSG00000124116 WAP four-disulfide core domain 3 20 45747944-45791932 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 19 testis: 31.8 breast: 1.6 -TTPAL C20orf121, dJ179M20.3 ENSG00000124120 Tocopherol (alpha) transfer protein-like 20 44475886-44494603 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046957, HPA066532 Uncertain Approved Golgi apparatus
Cytosol Mixed skin: 14.9 -PREX1 KIAA1415, P-REX1 ENSG00000124126 Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 20 48624252-48827883 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001927 Supported Supported Vesicles
Cytosol Expressed in all spleen: 61.8 -KCNS1 Kv9.1 ENSG00000124134 Potassium voltage-gated channel, modifier subfamily S, member 1 20 45092310-45101112 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 9.3;gallbladder: 3.8;seminal vesicle: 4.2 testis: 1.7 -SLC12A5 KCC2, KIAA1176 ENSG00000124140 Solute carrier family 12 (potassium/chloride transporter), member 5 20 46021690-46060152 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA072058 Supported Tissue enriched 8 cerebral cortex: 94.5 adrenal gland: 12.0 -ARHGAP40 C20orf95, dJ1100H13.4 ENSG00000124143 Rho GTPase activating protein 40 20 38601934-38651035 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA042636, HPA042840 Uncertain Supported Nucleoplasm
Plasma membrane
Centrosome
Cytosol Group enriched 7 breast: 37.4;epididymis: 43.2;esophagus: 12.7;seminal vesicle: 11.2;skin: 53.9 stomach: 4.3 -SDC4 amphiglycan, ryudocan, SYND4 ENSG00000124145 Syndecan 4 20 45325288-45348424 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005716, CAB013240 Supported Approved Golgi apparatus
Plasma membrane Expressed in all lung: 250.5 -NCOA3 ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1 ENSG00000124151 Nuclear receptor coactivator 3 20 47501902-47656877 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009800, HPA024210 Supported Supported Nucleoplasm
Cytosol Expressed in all lymph node: 45.3 -PIGT ENSG00000124155 Phosphatidylinositol glycan anchor biosynthesis, class T 20 45416077-45426244 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 158.8 -SEMG2 SGII ENSG00000124157 Semenogelin II 20 45221300-45224458 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042767, HPA042835 Supported Tissue enriched 28 seminal vesicle: 13953.0 prostate: 501.7 -MATN4 ENSG00000124159 Matrilin 4 20 45293445-45308529 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 breast: 3.0;pancreas: 5.9;skin: 3.5 cervix: 1.4 -NCOA5 bA465L10.6, CIA ENSG00000124160 Nuclear receptor coactivator 5 20 46060985-46089952 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050231 Uncertain Supported Nucleus
Actin filaments Expressed in all testis: 47.8 -VAPB ALS8, VAP-B, VAP-C ENSG00000124164 VAMP (vesicle-associated membrane protein)-associated protein B and C 20 58389122-58451101 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013144, CAB013722 Supported Validated Endoplasmic reticulum Expressed in all cerebral cortex: 42.5 -PARD6B PAR-6B ENSG00000124171 Par-6 family cell polarity regulator beta 20 50731544-50756795 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013376 Uncertain Supported Cytosol Mixed kidney: 16.7 -ATP5E ENSG00000124172 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 20 59025467-59032382 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all appendix: 137.1 -CHD6 CHD5, dJ620E11.1, FLJ22369, KIAA1335, RIGB ENSG00000124177 Chromodomain helicase DNA binding protein 6 20 41402101-41618494 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015543 Approved Nucleus Expressed in all parathyroid gland: 31.0 -PLCG1 NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1 ENSG00000124181 Phospholipase C, gamma 1 20 41136960-41196801 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004277, HPA036681, HPA036682 Approved Supported Cytosol Expressed in all endometrium: 47.4 -TOX2 C20orf100, dJ1108D11.2, GCX-1 ENSG00000124191 TOX high mobility group box family member 2 20 43914864-44069616 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049900, HPA058396 Approved Supported Nucleoplasm Mixed parathyroid gland: 19.5 -SRSF6 B52, SFRS6, SRP55 ENSG00000124193 Serine/arginine-rich splicing factor 6 20 43457928-43464247 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029005, CAB034889 Supported Supported Nuclear speckles Expressed in all endometrium: 82.9 -GDAP1L1 ENSG00000124194 Ganglioside induced differentiation associated protein 1-like 1 20 44247099-44280917 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054182, HPA063265 Approved Approved Endoplasmic reticulum Tissue enriched 20 cerebral cortex: 55.7 adrenal gland: 2.8 -GTSF1L C20orf65, dJ1028D15.4, FAM112A ENSG00000124196 Gametocyte specific factor 1-like 20 43726164-43726998 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA054694 Supported Tissue enriched 156 testis: 267.7 lymph node: 1.7 -ARFGEF2 BIG2 ENSG00000124198 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 20 48921890-49036693 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026078, CAB026382 Supported Supported Golgi apparatus Expressed in all parathyroid gland: 171.2 -ZNFX1 FLJ11277, KIAA1404 ENSG00000124201 Zinc finger, NFX1-type containing 1 20 49237946-49278426 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046629 Approved Approved Mitochondria Expressed in all lung: 27.1 -ZNF831 C20orf174, dJ492J12.1 ENSG00000124203 Zinc finger protein 831 20 59191020-59259113 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA016839 Uncertain Tissue enhanced 0 lymph node: 7.3 tonsil: 3.7 -EDN3 ET3 ENSG00000124205 Endothelin 3 20 59300427-59325992 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 duodenum: 39.3;small intestine: 40.2 thyroid gland: 36.2 -CSE1L CAS, CSE1, XPO2 ENSG00000124207 CSE1 chromosome segregation 1-like (yeast) 20 49046246-49096960 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002140, HPA038059, HPA038060 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 158.9 -TMEM189-UBE2V1 CROC-1B, Kua-UEV ENSG00000124208 TMEM189-UBE2V1 readthrough 20 50081124-50153637 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA052535, HPA053186 Supported Nucleoplasm Mixed placenta: 5.5 -RAB22A ENSG00000124209 RAB22A, member RAS oncogene family 20 58309696-58367507 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058894, HPA066920 Approved Uncertain Centrosome Expressed in all parathyroid gland: 22.8 -PTGIS CYP8A1, PGIS ENSG00000124212 Prostaglandin I2 (prostacyclin) synthase 20 49503874-49568146 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009517, HPA014193 Approved Mixed fallopian tube: 77.4 -STAU1 PPP1R150, STAU ENSG00000124214 Staufen double-stranded RNA binding protein 1 20 49113339-49188367 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020839, HPA049892 Approved Supported Cytosol Expressed in all parathyroid gland: 138.2 -CDH26 VR20 ENSG00000124215 Cadherin 26 20 59958427-60034011 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA015722, HPA047578 Uncertain Approved Plasma membrane
Microtubules Tissue enhanced 0 prostate: 19.8 urinary bladder: 6.3 -SNAI1 SLUGH2, SNA, SNAH, SNAIL, SNAIL1 ENSG00000124216 Snail family zinc finger 1 20 49982999-49988886 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB005883 Supported Supported Nucleus
Cytosol Tissue enhanced 0 gallbladder: 26.3 thyroid gland: 13.3 -MOCS3 dJ914P20.3, UBA4 ENSG00000124217 Molybdenum cofactor synthesis 3 20 50958826-50963931 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027556 Uncertain Mixed testis: 5.7 -STX16 hsyn16, SYN16 ENSG00000124222 Syntaxin 16 20 58651253-58679526 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041019, HPA042033 Uncertain Validated Vesicles Expressed in all skin: 64.0 -PMEPA1 STAG1, TMEPAI ENSG00000124225 Prostate transmembrane protein, androgen induced 1 20 57648392-57711536 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072291 Supported Vesicles Tissue enhanced 0 cervix, uterine: 145.4;prostate: 181.8 endometrium: 60.1 -RNF114 PSORS12, ZNF313 ENSG00000124226 Ring finger protein 114 20 49936336-49953892 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021184 Approved Supported Plasma membrane
Cytosol Expressed in all testis: 149.3 -ANKRD60 bA196N14.3, C20orf86 ENSG00000124227 Ankyrin repeat domain 60 20 58218495-58228653 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA060561 Uncertain Tissue enriched 47 testis: 4.7 adipose tissue: 0.0 -DDX27 dJ686N3.1, DRS1 ENSG00000124228 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 20 49219295-49244077 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047087 Uncertain Approved Nucleoli Expressed in all testis: 46.1 -RBPJL RBP-L, RBPSUHL, SUH, SUHL ENSG00000124232 Recombination signal binding protein for immunoglobulin kappa J region-like 20 45306851-45317824 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level CAB006846 Supported Tissue enriched 151 pancreas: 205.7 stomach: 1.3 -SEMG1 CT103, SEMG ENSG00000124233 Semenogelin I 20 45206997-45209772 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042476 Supported Tissue enriched 41 seminal vesicle: 41038.6 prostate: 1007.2 -C20orf85 bA196N14.1, LLC1 ENSG00000124237 Chromosome 20 open reading frame 85 20 58150904-58161150 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA058271, HPA065540 Supported Tissue enriched 8 fallopian tube: 719.2 testis: 91.4 -BCAS4 CNOL, FLJ20495 ENSG00000124243 Breast carcinoma amplified sequence 4 20 50794894-50882676 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038812 Uncertain Approved Intermediate filaments
Cytosol Tissue enhanced 0 lymph node: 25.7 tonsil: 22.0 -KCNK15 dJ781B1.1, K2p15.1, KCNK11, KCNK14, KIAA0237, KT3.3, TASK-5, TASK5 ENSG00000124249 Potassium channel, two pore domain subfamily K, member 15 20 44745780-44752313 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA064861 Uncertain Tissue enhanced 0 fallopian tube: 8.0 testis: 2.9 -TP53TG5 C20orf10, CLG01, dJ453C12.5 ENSG00000124251 TP53 target 5 20 45372563-45407889 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041979 Supported Tissue enriched 12 testis: 22.1 cerebral cortex: 1.8 -PCK1 PEPCK-C ENSG00000124253 Phosphoenolpyruvate carboxykinase 1 (soluble) 20 57561080-57568112 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006277, HPA006507, CAB017027 Approved Tissue enhanced 0 kidney: 423.6;liver: 320.1 small intestine: 160.7 -ZBP1 C20orf183, DAI, dJ718J7.3, DLM-1, DLM1 ENSG00000124256 Z-DNA binding protein 1 20 57603846-57620576 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041256 Supported Mixed spleen: 31.1 -NEURL2 C20orf163, dJ337O18.6, FLJ30259, Ozz, Ozz-E3 ENSG00000124257 Neuralized E3 ubiquitin protein ligase 2 20 45888625-45891287 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043402, HPA059842 Approved Approved Vesicles Mixed ovary: 8.6 -MAGEA10 CT1.10, MAGE10, MGC10599 ENSG00000124260 Melanoma antigen family A10 X 152133310-152138578 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003333, HPA070780 Approved Supported Nucleoplasm
Cytosol Group enriched 13 placenta: 13.5;testis: 4.8 skin: 0.7 -MTRR cblE ENSG00000124275 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 5 7851186-7906025 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038113 Supported Approved Nucleoplasm
Intermediate filaments
Cytosol Expressed in all kidney: 20.4 -FASTKD3 FLJ23274, MGC5297 ENSG00000124279 FAST kinase domains 3 5 7859159-7869037 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068525, HPA074462 Approved Supported Nucleus
Mitochondria Mixed parathyroid gland: 10.4 -PEPD ENSG00000124299 Peptidase D 19 33386950-33521794 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015599 Approved Approved Nucleoplasm Expressed in all kidney: 341.0 -CHST8 GALNAC-4-ST1 ENSG00000124302 Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 19 33621955-33773509 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 2.5 breast: 1.4 -IQSEC2 KIAA0522, MRX1 ENSG00000124313 IQ motif and Sec7 domain 2 X 53232876-53321324 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003973 Approved Vesicles Tissue enhanced 0 cerebral cortex: 30.6 parathyroid gland: 8.6 -VAMP7 SYBL1, TI-VAMP, VAMP-7 ENSG00000124333 Vesicle-associated membrane protein 7 X 155881293-155943769 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036733 Approved Supported Vesicles Expressed in all placenta: 56.8 -IL9R CD129 ENSG00000124334 Interleukin 9 receptor X 155997581-156010817 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB010497 Uncertain Tissue enhanced 0 urinary bladder: 8.8 lymph node: 2.9 -XG PBDX ENSG00000124343 Xg blood group X 2752050-2815927 Blood group antigen proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 41.1 breast: 15.6 -STAMBP AMSH ENSG00000124356 STAM binding protein 2 73828916-73873659 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035800 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all cerebral cortex: 39.2 -NAGK GNK ENSG00000124357 N-acetylglucosamine kinase 2 71064344-71079805 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035206, HPA035207 Supported Approved Nucleus
Cytosol Expressed in all esophagus: 148.5 -MCEE GLOD2 ENSG00000124370 Methylmalonyl CoA epimerase 2 71109684-71130239 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035196 Approved Nucleoli Expressed in all breast: 40.7 -PAIP2B KIAA1155 ENSG00000124374 Poly(A) binding protein interacting protein 2B 2 71182739-71227083 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046784, HPA072371 Approved Approved Cytosol Mixed cerebral cortex: 24.6 -SNRNP27 RY1 ENSG00000124380 Small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 2 69893560-69905575 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034541 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 43.5 -MPHOSPH10 CT90, MPP10, MPP10P, PPP1R106 ENSG00000124383 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 2 71130314-71150101 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035059, HPA035060, HPA049907 Supported Validated Nucleoli Expressed in all prostate: 35.0 -IL17C CX2, IL-17C, IL-21, MGC126884, MGC138401 ENSG00000124391 Interleukin 17C 16 88638591-88640473 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA065051 Supported Tissue enriched 6 endometrium: 3.5 gallbladder: 0.6 -ATP8A1 ATPIA ENSG00000124406 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 4 42408373-42657105 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049948, HPA052935 Approved Supported Vesicles Tissue enhanced 0 parathyroid gland: 67.5;thyroid gland: 66.3 cerebral cortex: 58.4 -USP22 KIAA1063, USP3L ENSG00000124422 Ubiquitin specific peptidase 22 17 20999593-21043760 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044980 Supported Supported Nuclear speckles Expressed in all cerebral cortex: 154.5 -POF1B FLJ22792, POF ENSG00000124429 Premature ovarian failure, 1B X 85277396-85379743 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002033, HPA050027 Uncertain Supported Nucleoplasm
Golgi apparatus Tissue enhanced 0 skin: 144.8 rectum: 53.7 -HIF3A bHLHe17, IPAS, MOP7, PASD7 ENSG00000124440 Hypoxia inducible factor 3, alpha subunit 19 46297046-46343433 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA041141 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 placenta: 39.5 spleen: 20.3 -ZNF576 MGC2508 ENSG00000124444 Zinc finger protein 576 19 43596392-43601157 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA050064 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all cerebral cortex: 14.7 -IRGC CINEMA, Iigp5, IRGC1 ENSG00000124449 Immunity-related GTPase family, cinema 19 43716010-43720021 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046769, HPA060064 Supported Tissue enriched 629 testis: 62.9 adipose tissue: 0.0 -ZNF45 ZNF13 ENSG00000124459 Zinc finger protein 45 19 43912629-43935278 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA038611, HPA075124 Uncertain Supported Nucleoplasm Mixed parathyroid gland: 18.1 -LYPD3 C4.4A ENSG00000124466 LY6/PLAUR domain containing 3 19 43460787-43465660 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041529, HPA041797, HPA077859 Supported Approved Endoplasmic reticulum
Vesicles Group enriched 5 esophagus: 676.5;skin: 594.5 tonsil: 118.9 -PSG8 ENSG00000124467 Pregnancy specific beta-1-glycoprotein 8 19 42752686-42855691 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046327 Approved Tissue enriched 12 placenta: 9.1 parathyroid gland: 0.7 -CEACAM8 CD66b, CGM6 ENSG00000124469 Carcinoembryonic antigen-related cell adhesion molecule 8 19 42580241-42740384 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033676 Approved Tissue enriched 88 bone marrow: 150.9 lung: 1.7 -NDP EVR2, norrin ENSG00000124479 Norrie disease (pseudoglioma) X 43948776-43973504 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003095 Uncertain Approved Nucleus
Nucleoli
Vesicles Tissue enhanced 0 ovary: 53.0 fallopian tube: 30.9 -USP9X DFFRX, FAF, MRX99 ENSG00000124486 Ubiquitin specific peptidase 9, X-linked X 41085635-41236579 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB011618, HPA047417, CAB070164 Approved Uncertain Vesicles Expressed in all parathyroid gland: 88.6 -CRISP2 CRISP-2, CT36, GAPDL5, TPX1 ENSG00000124490 Cysteine-rich secretory protein 2 6 49692358-49713590 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031248 Supported Tissue enriched 43 testis: 846.9 fallopian tube: 19.5 -F13A1 F13A ENSG00000124491 Coagulation factor XIII, A1 polypeptide 6 6144085-6321013 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001804, CAB002155 Supported Expressed in all placenta: 664.9 -GRM4 GPRC1D, mGlu4, MGLUR4 ENSG00000124493 Glutamate receptor, metabotropic 4 6 34018645-34155622 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB022096 Supported Tissue enhanced 0 cerebral cortex: 2.9 testis: 0.7 -TRERF1 BCAR2, dJ139D8.5, HSA277276, RAPA, TReP-132 ENSG00000124496 Transcriptional regulating factor 1 6 42224931-42452051 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027771, HPA051273, HPA059943 Supported Validated Nucleoplasm
Cytosol Mixed testis: 11.0 -PACSIN1 SDPI ENSG00000124507 Protein kinase C and casein kinase substrate in neurons 1 6 34466061-34535231 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009929, HPA028852, HPA055491 Supported Approved Nucleus
Vesicles Tissue enriched 32 cerebral cortex: 134.1 lymph node: 4.2 -BTN2A2 BT2.2, BTF2, BTN2.2 ENSG00000124508 Butyrophilin, subfamily 2, member A2 6 26383096-26394874 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051504 Uncertain Supported Mitochondria Mixed lymph node: 38.1 -SIRT5 ENSG00000124523 Sirtuin 5 6 13574529-13615158 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021798, HPA022002, HPA022992 Approved Validated Mitochondria Expressed in all parathyroid gland: 20.2 -MRS2 MRS2L ENSG00000124532 MRS2 magnesium transporter 6 24402908-24426194 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017642 Uncertain Expressed in all thyroid gland: 29.8 -WRNIP1 bA420G6.2, FLJ22526, WHIP ENSG00000124535 Werner helicase interacting protein 1 6 2765414-2786952 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031752, HPA031753 Supported Approved Nucleoplasm Expressed in all parathyroid gland: 77.3 -RRP36 C6orf153, dJ20C7.4 ENSG00000124541 Ribosomal RNA processing 36 6 43021645-43034156 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029904, HPA029905 Uncertain Supported Nucleus
Nucleoli Expressed in all parathyroid gland: 60.2 -BTN1A1 BT, BTN, BTN1 ENSG00000124557 Butyrophilin, subfamily 1, member A1 6 26501221-26510422 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011126 Supported Tissue enriched 45 breast: 37.0 tonsil: 0.8 -SNRPC U1-C, Yhc1 ENSG00000124562 Small nuclear ribonucleoprotein polypeptide C 6 34757406-34773794 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034338, HPA042419, HPA055490 Supported Validated Nucleoplasm Expressed in all testis: 150.7 -SLC17A3 NPT4 ENSG00000124564 Solute carrier family 17 (organic anion transporter), member 3 6 25833066-25882286 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016569 Uncertain Tissue enriched 9 kidney: 167.2 liver: 18.5 -SLC17A1 NAPI-1, NPT1 ENSG00000124568 Solute carrier family 17 (organic anion transporter), member 1 6 25782897-25832059 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA050513 Approved Golgi apparatus Tissue enriched 7 kidney: 173.1 liver: 25.2 -SERPINB6 CAP, DFNB91, PI6, PTI ENSG00000124570 Serpin peptidase inhibitor, clade B (ovalbumin), member 6 6 2948159-2972165 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009668, HPA012736 Supported Approved Centrosome Expressed in all testis: 254.5 -XPO5 KIAA1291 ENSG00000124571 Exportin 5 6 43522330-43576075 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012357, HPA018402, HPA023959, HPA029909, HPA029910 Supported Validated Nucleoplasm Expressed in all testis: 43.4 -ABCC10 EST182763, MRP7, SIMRP7 ENSG00000124574 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 6 43427366-43450430 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041607, HPA045464 Approved Expressed in all smooth muscle: 12.4 -HIST1H1D H1.3, H1d, H1F3, H1s-2 ENSG00000124575 Histone cluster 1, H1d 6 26234268-26234933 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055907 Supported Tissue enriched 6 bone marrow: 17.5 lymph node: 3.0 -PEX6 PAF-2, PXAAA1 ENSG00000124587 Peroxisomal biogenesis factor 6 6 42963870-42979220 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025924, HPA074179 Supported Approved Nucleoplasm
Vesicles Expressed in all fallopian tube: 36.4 -NQO2 DHQV, DIA6, NMOR2, QR2 ENSG00000124588 NAD(P)H dehydrogenase, quinone 2 6 2987987-3028869 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021283, HPA021332 Supported Supported Nucleoplasm
Cytosol Expressed in all kidney: 201.3 -PRICKLE4 C6orf49, DKFZp761H221, OEBT ENSG00000124593 Prickle homolog 4 6 41780349-41790141 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA031240 Uncertain Mitotic spindle
Microtubule organizing center Mixed endometrium: 4.4 -OARD1 C6orf130, dJ34B21.3, MGC19570, TARG1 ENSG00000124596 O-acyl-ADP-ribose deacylase 1 6 41033627-41097787 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029036 Approved Approved Nucleus
Nucleoli Expressed in all testis: 109.9 -UNC5CL MGC34763, ZUD ENSG00000124602 Unc-5 family C-terminal like 6 41026911-41039217 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015725 Supported Approved Centrosome Tissue enhanced 0 duodenum: 38.3;small intestine: 33.1;stomach: 24.0 kidney: 14.9 -AARS2 AARSL, bA444E17.1, KIAA1270 ENSG00000124608 Alanyl-tRNA synthetase 2, mitochondrial 6 44299654-44313326 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035636, HPA061396 Approved Validated Mitochondria Mixed parathyroid gland: 11.1 -HIST1H1A H1.1, H1a, H1F1 ENSG00000124610 Histone cluster 1, H1a 6 26017085-26017732 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043753 Supported Not detected testis: 0.2 -ZNF391 dJ153G14.3 ENSG00000124613 Zinc finger protein 391 6 27374615-27403904 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA050886 Uncertain Mixed testis: 8.9 -RPS10 MGC88819, S10 ENSG00000124614 Ribosomal protein S10 6 34417454-34426125 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047268, HPA048084 Approved Supported Cytosol Expressed in all ovary: 2696.6 -MOCS1 MOCOD ENSG00000124615 Molybdenum cofactor synthesis 1 6 39899578-39934551 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045783, HPA058177, HPA075505 Uncertain Approved Plasma membrane
Cytosol Mixed placenta: 59.8 -HIST1H2BJ H2B/r, H2BFR ENSG00000124635 Histone cluster 1, H2bj 6 27125897-27132750 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 48.7 prostate: 10.9 -MED20 DKFZp586D2223, PRO0213, TRFP ENSG00000124641 Mediator complex subunit 20 6 41905354-41921139 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040717 Uncertain Approved Nucleoplasm
Centrosome Expressed in all placenta: 20.7 -OR2B6 dJ408B20.2, OR2B1, OR2B1P, OR2B5, OR2B6P, OR5-40, OR5-41, OR6-31 ENSG00000124657 Olfactory receptor, family 2, subfamily B, member 6 6 27957241-27958182 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected spleen: 0.3 -TBCC CFC ENSG00000124659 Tubulin folding cofactor C 6 42744481-42746096 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035073, HPA035074 Approved Validated Cytosol Expressed in all lymph node: 33.2 -SPDEF bA375E1.3, PDEF ENSG00000124664 SAM pointed domain containing ETS transcription factor 6 34537802-34556333 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055707 Supported Nucleus
Nucleoli Tissue enhanced 0 prostate: 154.8 breast: 42.1 -TCP11 D6S230E, FPPR, KIAA0229 ENSG00000124678 T-complex 11, testis-specific 6 35118071-35148610 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048311 Supported Tissue enriched 331 testis: 558.6 ovary: 1.6 -MAD2L1BP CMT2, dJ261G23.1, KIAA0110 ENSG00000124688 MAD2L1 binding protein 6 43629540-43640952 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028729 Supported Nucleus
Nuclear membrane
Nucleoli Expressed in all bone marrow: 32.6 -APOBEC2 ARCD1, ARP1 ENSG00000124701 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 6 41053304-41064511 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014252, HPA017957 Supported Group enriched 13 heart muscle: 115.6;skeletal muscle: 403.9 esophagus: 19.6 -KLHDC3 dJ20C7.3, hPeas, PEAS ENSG00000124702 Kelch domain containing 3 6 43014103-43021298 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030131, HPA030132, HPA030133, HPA030134 Uncertain Supported Nucleoplasm Expressed in all testis: 251.3 -GNMT ENSG00000124713 Glycine N-methyltransferase 6 42960758-42963880 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027501 Supported Approved Cytosol Group enriched 9 liver: 154.6;pancreas: 55.8;prostate: 34.2 breast: 9.3 -DNAH8 hdhc9 ENSG00000124721 Dynein, axonemal, heavy chain 8 6 38715341-39030529 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028447 Uncertain Tissue enhanced 0 testis: 14.2 prostate: 3.4 -TREM1 CD354, TREM-1 ENSG00000124731 Triggering receptor expressed on myeloid cells 1 6 41267926-41286719 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA005563 Uncertain Tissue enhanced 0 appendix: 68.9;bone marrow: 63.1;lung: 103.1 adipose tissue: 26.7 -MEA1 MEA ENSG00000124733 Male-enhanced antigen 1 6 43012094-43013968 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017921 Approved Approved Nucleus
Cytosol Expressed in all testis: 245.3 -KLHL31 bA345L23.2, BKLHD6, KBTBD1 ENSG00000124743 Kelch-like family member 31 6 53647901-53665708 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 heart muscle: 30.3;skeletal muscle: 51.2 adipose tissue: 9.0 -COL21A1 ENSG00000124749 Collagen, type XXI, alpha 1 6 56056590-56394094 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031210, HPA031212, HPA031213 Uncertain Supported Cytosol Tissue enhanced 0 cervix, uterine: 36.5;placenta: 38.7 endometrium: 19.5 -CDKN1A CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1 ENSG00000124762 Cyclin-dependent kinase inhibitor 1A (p21, Cip1) 6 36676460-36687339 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000064, HPA005946, CAB069401 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all gallbladder: 205.5 -SOX4 ENSG00000124766 SRY (sex determining region Y)-box 4 6 21592769-21598619 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA029901 Approved Supported Nucleoplasm
Mitochondria Expressed in all endometrium: 80.4 -GLO1 GLOD1 ENSG00000124767 Glyoxalase I 6 38675925-38703141 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB040541, CAB040542, HPA059791 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all prostate: 274.7 -CPNE5 COPN5, CPN5, KIAA1599 ENSG00000124772 Copine V 6 36740775-36840002 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031369 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 119.3 testis: 34.7 -KCNK17 K2p17.1, TALK-2, TALK2, TASK-4, TASK4 ENSG00000124780 Potassium channel, two pore domain subfamily K, member 17 6 39299001-39314553 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043892 Uncertain Tissue enhanced 0 lung: 5.6 placenta: 5.2 -RREB1 HNT ENSG00000124782 Ras responsive element binding protein 1 6 7107597-7251980 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001756, HPA034843 Approved Supported Nucleoli fibrillar center
Nuclear speckles Expressed in all parathyroid gland: 22.9 -SSR1 TRAPA ENSG00000124783 Signal sequence receptor, alpha 6 7268306-7347446 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011276, HPA017062 Supported Supported Endoplasmic reticulum Expressed in all thyroid gland: 140.5 -RIOK1 AD034, bA288G3.1, FLJ30006, RRP10 ENSG00000124784 RIO kinase 1 6 7389496-7418037 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017866, HPA051446 Supported Approved Nucleoli
Nuclear speckles
Cytosol Expressed in all testis: 29.5 -NRN1 NRN ENSG00000124785 Neuritin 1 6 5997999-6007605 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 153.0 adipose tissue: 61.4 -SLC35B3 C6orf196, CGI-19, dJ453H5.1, PAPST2 ENSG00000124786 Solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 6 8413068-8435483 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054661, HPA057801 Approved Expressed in all epididymis: 62.2 -RPP40 bA428J1.3, RNASEP1 ENSG00000124787 Ribonuclease P/MRP 40kDa subunit 6 4994732-5004063 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035685, HPA035686 Uncertain Approved Nucleoplasm Mixed adrenal gland: 11.9 -ATXN1 ATX1, D6S504E, SCA1 ENSG00000124788 Ataxin 1 6 16299112-16761491 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008335, HPA070756 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all cerebral cortex: 17.5 -NUP153 HNUP153 ENSG00000124789 Nucleoporin 153kDa 6 17615035-17706834 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027896, HPA027897, HPA027898 Supported Validated Nuclear membrane Expressed in all testis: 53.3 -DEK D6S231E ENSG00000124795 DEK proto-oncogene 6 18223868-18264823 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015226, HPA054505, HPA057799 Supported Validated Nucleus Expressed in all thyroid gland: 158.3 -EEF1E1 AIMP3, P18 ENSG00000124802 Eukaryotic translation elongation factor 1 epsilon 1 6 8073360-8102578 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027901, HPA057866 Approved Supported Nucleus
Cytosol Expressed in all testis: 101.7 -CRISP1 AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP ENSG00000124812 Cysteine-rich secretory protein 1 6 49834257-49877096 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028445 Supported Tissue enriched 20 epididymis: 1884.0 seminal vesicle: 95.6 -RUNX2 AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1 ENSG00000124813 Runt-related transcription factor 2 6 45328157-45664349 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008374, HPA022040, CAB062561, CAB068226 Supported Validated Nucleoplasm Mixed cervix: 10.5 -OPN5 dJ402H5.1, neuropsin, TMEM13 ENSG00000124818 Opsin 5 6 47781982-47832780 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA026084 Supported Tissue enriched 42 testis: 4.3 heart muscle: 0.1 -GCM2 GCMB, hGCMb ENSG00000124827 Glial cells missing homolog 2 (Drosophila) 6 10873223-10881941 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 985 parathyroid gland: 762.5 testis: 0.7 -LRRFIP1 FLAP-1, FLIIAP1, GCF-2, HUFI-1, TRIP ENSG00000124831 Leucine rich repeat (in FLII) interacting protein 1 2 237627576-237813682 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006979 Approved Supported Cytosol Expressed in all parathyroid gland: 123.5 -RAB17 ENSG00000124839 RAB17, member RAS oncogene family 2 237574322-237601614 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035176 Approved Mixed small intestine: 65.7 -CXCL6 CKA-3, GCP-2, SCYB6 ENSG00000124875 Chemokine (C-X-C motif) ligand 6 4 73836497-73849064 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 gallbladder: 50.4;spleen: 114.7 urinary bladder: 33.6 -EREG ER ENSG00000124882 Epiregulin 4 74365143-74388751 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054373 Approved Vesicles Tissue enriched 6 bone marrow: 82.5 appendix: 14.7 -TRIM51 SPRYD5, TRIM51A ENSG00000124900 Tripartite motif-containing 51 11 55883297-55891810 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044988 Uncertain Not detected testis: 0.4 -MYRF C11orf9, MRF, Ndt80, pqn-47 ENSG00000124920 Myelin regulatory factor 11 61752642-61788518 Enzymes, Plasma proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018310 Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 67.6;stomach: 62.4 gallbladder: 38.4 -SCGB1D2 LIPB, LPHB ENSG00000124935 Secretoglobin, family 1D, member 2 11 62242210-62244808 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035318 Approved Group enriched 9 breast: 1426.3;cervix, uterine: 5141.6 epididymis: 377.9 -SCGB2A1 LPHC, MGB2, MGC71973, UGB3 ENSG00000124939 Secretoglobin, family 2A, member 1 11 62208668-62213939 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034584 Supported Group enriched 6 cervix, uterine: 2835.4;epididymis: 1634.2 fallopian tube: 376.7 -AHNAK MGC5395 ENSG00000124942 AHNAK nucleoprotein 11 62433542-62556235 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019010, HPA019070, HPA026643 Uncertain Supported Plasma membrane
Cytosol Expressed in all skin: 398.0 -EMC3 TMEM111 ENSG00000125037 ER membrane protein complex subunit 3 3 9962537-10011116 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042372 Approved Approved Microtubules
Cytosol Expressed in all testis: 90.7 -SSUH2 C3orf32, fls485, ssu-2 ENSG00000125046 Ssu-2 homolog (C. elegans) 3 8619400-8745040 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049777 Uncertain Tissue enhanced 0 duodenum: 4.3;small intestine: 4.0;testis: 4.0 spleen: 1.6 -WNT1 INT1 ENSG00000125084 Wingless-type MMTV integration site family, member 1 12 48978453-48981676 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed cerebral cortex: 1.3 -SH3TC1 FLJ20356 ENSG00000125089 SH3 domain and tetratricopeptide repeats 1 4 8182072-8241803 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038132, HPA056807 Uncertain Approved Nucleus
Nucleoli
Cytosol Mixed spleen: 12.8 -CNOT1 AD-005, CDC39, KIAA1007, NOT1, NOT1H ENSG00000125107 CCR4-NOT transcription complex, subunit 1 16 58519951-58629886 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046577, HPA049664 Approved Supported Cytosol Expressed in all testis: 206.0 -LRRC29 FBL9, FBXL9 ENSG00000125122 Leucine rich repeat containing 29 16 67207139-67227048 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA034998 Uncertain Uncertain Nucleoplasm Mixed testis: 4.7 -BBS2 BBS ENSG00000125124 Bardet-Biedl syndrome 2 16 56466836-56520283 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041315 Approved Expressed in all adrenal gland: 91.7 -MT1G MT1, MT1K ENSG00000125144 Metallothionein 1G 16 56666731-56668065 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 kidney: 2338.0;thyroid gland: 4892.9 liver: 1261.9 -MT2A MT2 ENSG00000125148 Metallothionein 2A 16 56608199-56609497 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all adrenal gland: 1206.6 -C16orf70 C16orf6, FLJ12076, lin-10, LIN10 ENSG00000125149 Chromosome 16 open reading frame 70 16 67109958-67148539 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041131, HPA041214 Approved Approved Nuclear speckles
Cytosol Expressed in all parathyroid gland: 33.2 -GOT2 KAT4, KATIV, mitAAT ENSG00000125166 Glutamic-oxaloacetic transaminase 2, mitochondrial 16 58707131-58734357 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018139 Supported Expressed in all skeletal muscle: 240.3 -DOK4 FLJ10488 ENSG00000125170 Docking protein 4 16 57471922-57487327 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA055849 Supported Approved Vesicles
Microtubules
Cytokinetic bridge Expressed in all small intestine: 55.8 -PIWIL1 CT80.1, HIWI, PIWI ENSG00000125207 Piwi-like RNA-mediated gene silencing 1 12 130337887-130372637 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012217, HPA018798 Supported Tissue enriched 33 testis: 5.2 spleen: 0.1 -GPR18 ENSG00000125245 G protein-coupled receptor 18 13 99254714-99261744 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA013873 Supported Tissue enhanced 0 lymph node: 52.2;testis: 25.1;tonsil: 32.9 appendix: 17.0 -CLYBL CLB ENSG00000125246 Citrate lyase beta like 13 99606669-99897134 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039959, HPA040691 Supported Approved Cytosol Expressed in all kidney: 66.9 -TMTC4 FLJ14624, FLJ22153 ENSG00000125247 Transmembrane and tetratricopeptide repeat containing 4 13 100603927-100675093 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA016489 Uncertain Approved Vesicles Expressed in all cerebral cortex: 26.5 -RAP2A K-REV, RAP2 ENSG00000125249 RAP2A, member of RAS oncogene family 13 97434222-97469128 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018552 Uncertain Expressed in all cerebral cortex: 75.1 -SLC10A2 ASBT, ISBT ENSG00000125255 Solute carrier family 10 (sodium/bile acid cotransporter), member 2 13 103043998-103066846 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA004795 Approved Group enriched 32 duodenum: 21.6;kidney: 15.3;small intestine: 52.2 gallbladder: 0.9 -ABCC4 EST170205, MOAT-B, MOATB, MRP4 ENSG00000125257 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 13 95019829-95301446 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002476 Supported Approved Nucleoli
Plasma membrane
Cytosol Tissue enhanced 0 prostate: 68.5 epididymis: 23.3 -EFNB2 EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228 ENSG00000125266 Ephrin-B2 13 106489731-106535114 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008999, CAB009368 Supported Supported Nucleoplasm
Cytosol Mixed placenta: 48.1 -SOX21 SOX25 ENSG00000125285 SRY (sex determining region Y)-box 21 13 94709622-94712399 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA064084 Approved Nucleus Group enriched 6 cerebral cortex: 18.0;esophagus: 6.9;skin: 19.4;stomach: 33.9 tonsil: 3.2 -TM9SF2 P76 ENSG00000125304 Transmembrane 9 superfamily member 2 13 99501417-99564006 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005657 Supported Expressed in all thyroid gland: 201.3 -C17orf53 MGC3130 ENSG00000125319 Chromosome 17 open reading frame 53 17 44141906-44162476 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023004, HPA023393, HPA024430 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 12.5 bone marrow: 6.3 -KIF25 KNSL3 ENSG00000125337 Kinesin family member 25 6 167996241-168045089 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046153 Uncertain Tissue enhanced 0 adipose tissue: 8.7 placenta: 1.8 -IRF1 MAR ENSG00000125347 Interferon regulatory factor 1 5 132481609-132490798 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB011662, HPA063131 Supported Supported Nucleoplasm
Cytosol Expressed in all spleen: 137.5 -UPF3B HUPF3B, MRX62, RENT3B, UPF3X ENSG00000125351 UPF3 regulator of nonsense transcripts homolog B (yeast) X 119834022-119852998 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001592, HPA001800, HPA001882 Approved Validated Nucleus
Nucleoli
Cytosol Expressed in all cerebral cortex: 18.4 -RNF113A Cwc24, RNF113, ZNF183 ENSG00000125352 Ring finger protein 113A X 119870475-119871827 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000160 Approved Expressed in all lymph node: 24.9 -SEPT6 KIAA0128, MGC16619, MGC20339, SEP2, SEPT2 ENSG00000125354 Septin 6 X 119615724-119693370 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003459, HPA005665 Supported Mixed lymph node: 142.3 -TMEM255A FAM70A, FLJ20716 ENSG00000125355 Transmembrane protein 255A X 120258650-120311556 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048470 Uncertain Uncertain Nucleus
Nuclear bodies Tissue enhanced 0 ovary: 23.4 cervix: 10.4 -NDUFA1 CI-MWFE, MWFE ENSG00000125356 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa X 119871487-119876662 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029768, HPA054359 Supported Supported Mitochondria
Cytosol Expressed in all skeletal muscle: 224.9 -AMELX AIH1, AMG ENSG00000125363 Amelogenin, X-linked X 11293413-11300761 Disease related genes, Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.4 -ATP5S ATPW, HSU79253 ENSG00000125375 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 14 50312326-50335558 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046967, HPA062690 Approved Approved Nucleoplasm
Mitochondria Mixed fallopian tube: 9.6 -BMP4 BMP2B ENSG00000125378 Bone morphogenetic protein 4 14 53949736-53958761 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB006863, HPA066235 Approved Mixed placenta: 63.6 -PTGER2 EP2 ENSG00000125384 Prostaglandin E receptor 2 (subtype EP2), 53kDa 14 52314305-52328606 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed cervix: 27.3 -FAM193A C4orf8, RES4-22 ENSG00000125386 Family with sequence similarity 193, member A 4 2625261-2732565 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043116 Approved Approved Plasma membrane
Cytosol Expressed in all testis: 41.5 -GRK4 GPRK2L, GPRK4 ENSG00000125388 G protein-coupled receptor kinase 4 4 2963608-3040747 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028737, HPA057023 Approved Supported Vesicles Tissue enriched 9 testis: 74.5 cerebral cortex: 8.2 -SOX9 CMD1, CMPD1, SRA1 ENSG00000125398 SRY (sex determining region Y)-box 9 17 72121020-72126420 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001758, CAB022456, CAB068240 Supported Validated Nucleoplasm Mixed cerebral cortex: 61.5 -TEKT3 FLJ32828 ENSG00000125409 Tektin 3 17 15303811-15341641 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044354 Uncertain Tissue enriched 6 testis: 46.0 fallopian tube: 7.4 -MYH2 IBM3, MYH2A, MYHas8, MyHC-2A, MyHC-IIa, MYHSA2 ENSG00000125414 Myosin, heavy chain 2, skeletal muscle, adult 17 10521148-10549957 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001349, CAB010760 Supported Tissue enriched 99 skeletal muscle: 4307.0 esophagus: 43.4 -HS3ST3B1 30ST3B1, 3OST3B1 ENSG00000125430 Heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 17 14301083-14349404 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA064126 Approved Vesicles Tissue enhanced 0 liver: 14.7 lymph node: 7.2 -SLC25A35 FLJ40217 ENSG00000125434 Solute carrier family 25, member 35 17 8287763-8295343 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051720 Uncertain Approved Vesicles
Mitochondria Mixed testis: 19.6 -MRPS7 MRP-S, RP-S7, RPMS7 ENSG00000125445 Mitochondrial ribosomal protein S7 17 75261674-75266373 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022522, HPA023007 Supported Approved Mitochondria Expressed in all heart muscle: 59.3 -GGA3 KIAA0154 ENSG00000125447 Golgi-associated, gamma adaptin ear containing, ARF binding protein 3 17 75236599-75262363 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022945, HPA024645 Approved Supported Golgi apparatus Expressed in all parathyroid gland: 22.1 -ARMC7 FLJ22160 ENSG00000125449 Armadillo repeat containing 7 17 75109952-75130265 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024229, HPA053076 Uncertain Supported Cytosol Expressed in all lung: 12.7 -NUP85 FLJ12549, NUP75 ENSG00000125450 Nucleoporin 85kDa 17 75205659-75235758 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061910, HPA062595 Supported Supported Nucleus
Cytosol Expressed in all testis: 34.1 -SLC25A19 DNC, MCPHA, MUP1, TPC ENSG00000125454 Solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 17 75272981-75289510 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 49.5 -MIF4GD AD023, MGC45027, MIFD ENSG00000125457 MIF4G domain containing 17 75266228-75271227 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051222 Approved Supported Nucleoli
Cytosol Expressed in all lymph node: 46.5 -NT5C cdN, DNT-1, DNT1, PN-I, UMPH2 ENSG00000125458 5', 3'-nucleotidase, cytosolic 17 75130225-75131795 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021581, HPA023632 Approved Supported Cytosol Expressed in all small intestine: 32.0 -MSTO1 FLJ10504, LST005, misato, MST ENSG00000125459 Misato 1, mitochondrial distribution and morphology regulator 1 155610205-155614967 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005899, HPA005914 Approved Approved Nuclear membrane
Cytosol Mixed parathyroid gland: 23.4 -C1orf61 CROC4 ENSG00000125462 Chromosome 1 open reading frame 61 1 156404250-156430701 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 131 cerebral cortex: 505.2 testis: 3.8 -TTF1 ENSG00000125482 Transcription termination factor, RNA polymerase I 9 132375548-132406851 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054837 Supported Supported Nucleus
Nucleoli Expressed in all thyroid gland: 18.2 -GTF3C4 KAT12, TFIIIC90 ENSG00000125484 General transcription factor IIIC, polypeptide 4, 90kDa 9 132670035-132694955 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069369 Supported Nucleus Expressed in all parathyroid gland: 16.7 -DDX31 FLJ13633, FLJ14578, FLJ23349, PPP1R25 ENSG00000125485 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 9 132592997-132670401 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020891 Supported Nucleoli
Golgi apparatus
Vesicles Expressed in all thyroid gland: 23.0 -BARHL1 ENSG00000125492 BarH-like homeobox 1 9 132582185-132590266 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA004809 Approved Not detected adipose tissue: 0.0 -KIR2DL1 47.11, CD158A, cl-42, nkat1, p58.1 ENSG00000125498 Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 19 54769811-54784322 CD markers, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected endometrium: 0.4 -PPP1R12C DKFZP434D0412, LENG3, MBS85, p84, p85 ENSG00000125503 Protein phosphatase 1, regulatory subunit 12C 19 55090913-55117559 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043532 Approved Expressed in all endometrium: 112.4 -MBOAT7 BB1, hMBOA-7, LENG4, LPIAT ENSG00000125505 Membrane bound O-acyltransferase domain containing 7 19 54173412-54189882 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055967 Approved Approved Cytosol Expressed in all cerebral cortex: 24.3 -SRMS C20orf148, dJ697K14.1, SRM ENSG00000125508 Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 20 63540810-63547504 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB044668, CAB044669, HPA073987 Uncertain Approved Intermediate filaments
Actin filaments
Cytosol Mixed stomach: 1.5 -OPRL1 KOR-3, NOCIR, OOR, ORL1 ENSG00000125510 Opiate receptor-like 1 20 64080173-64100643 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 12.3 testis: 4.8 -SLC2A4RG GEF, HDBP1, Si-1-2, Si-1-2-19 ENSG00000125520 SLC2A4 regulator 20 63739861-63743505 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA063050 Supported Nuclear speckles Expressed in all adipose tissue: 53.6 -NPBWR2 GPR8 ENSG00000125522 Neuropeptides B/W receptor 2 20 64105820-64107171 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level No evidence Evidence at protein level Not detected cerebral cortex: 0.1 -C20orf195 MGC5356 ENSG00000125531 Chromosome 20 open reading frame 195 20 63547891-63556708 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041341 Approved Nucleoplasm
Vesicles
Aggresome Tissue enriched 19 testis: 53.2 epididymis: 2.7 -BHLHE23 bA305P22.3, Beta4, BHLHB4, bHLHe23 ENSG00000125533 Basic helix-loop-helix family, member e23 20 63005927-63007035 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030575 Uncertain Not detected testis: 0.1 -PPDPF C20orf149, dJ697K14.9, exdpf ENSG00000125534 Pancreatic progenitor cell differentiation and proliferation factor 20 63520724-63522206 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA040929 Approved Nucleoplasm
Nucleoli
Microtubules Expressed in all stomach: 213.7 -IL1B IL-1B, IL1-BETA, IL1F2 ENSG00000125538 Interleukin 1, beta 2 112829751-112836903 Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 69.5;bone marrow: 106.7 adipose tissue: 52.7 -PLGLB2 PLGP1 ENSG00000125551 Plasminogen-like B2 2 87748087-87758793 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA053770 Approved Vesicles Tissue enriched 162 liver: 244.1 skin: 1.5 -IL37 FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7 ENSG00000125571 Interleukin 37 2 112912971-112918882 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA054371, HPA057950 Approved Supported Nucleoplasm
Vesicles Tissue enriched 7 skin: 162.6 breast: 22.0 -CHCHD5 C2orf9, MGC11104, MIC14 ENSG00000125611 Coiled-coil-helix-coiled-coil-helix domain containing 5 2 112584240-112589275 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038263 Approved Supported Mitochondria Expressed in all thyroid gland: 33.4 -PAX8 ENSG00000125618 Paired box 8 2 113215997-113278950 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA030062, HPA064554 Validated Nucleoplasm Tissue enriched 10 thyroid gland: 642.7 kidney: 65.0 -INSIG2 ENSG00000125629 Insulin induced gene 2 2 118088452-118110997 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB033861 Uncertain Expressed in all parathyroid gland: 27.9 -POLR1B FLJ10816, FLJ21921, RPA2, Rpo1-2 ENSG00000125630 Polymerase (RNA) I polypeptide B, 128kDa 2 112541915-112577150 Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037528 Supported Nucleoli
Cytosol Expressed in all parathyroid gland: 23.6 -CCDC93 FLJ10996 ENSG00000125633 Coiled-coil domain containing 93 2 117915478-118014133 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054183 Approved Supported Vesicles
Plasma membrane Expressed in all parathyroid gland: 24.5 -PSD4 EFA6B, TIC ENSG00000125637 Pleckstrin and Sec7 domain containing 4 2 113157325-113209396 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034722, HPA034723 Supported Mixed parathyroid gland: 33.3 -SLC25A23 APC2, FLJ30339, MGC2615 ENSG00000125648 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 19 6436079-6465203 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009675, HPA050883 Approved Supported Mitochondria Mixed cerebral cortex: 141.8 -PSPN PSP ENSG00000125650 Persephin 19 6375148-6379058 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB025366 Approved Mixed cerebral cortex: 1.4 -GTF2F1 BTF4, RAP74, TF2F1, TFIIF ENSG00000125651 General transcription factor IIF, polypeptide 1, 74kDa 19 6379569-6393981 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022793, HPA028707 Approved Validated Nucleus
Cell Junctions Expressed in all ovary: 93.6 -ALKBH7 MGC10974, SPATA11 ENSG00000125652 AlkB homolog 7 19 6372433-6375251 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039571, HPA039872 Supported Expressed in all testis: 252.8 -CLPP ENSG00000125656 Caseinolytic mitochondrial matrix peptidase proteolytic subunit 19 6361452-6368908 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010649 Supported Validated Mitochondria Expressed in all appendix: 50.0 -TNFSF9 4-1BB-L ENSG00000125657 Tumor necrosis factor (ligand) superfamily, member 9 19 6530999-6535928 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059857 Approved Golgi apparatus Mixed cerebral cortex: 3.5 -GRIA3 GluA3, GLUR3, GLURC, MRX94 ENSG00000125675 Glutamate receptor, ionotropic, AMPA 3 X 123184153-123490915 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058659 Uncertain Tissue enhanced 0 cerebral cortex: 56.8 adrenal gland: 11.4 -THOC2 CXorf3, dJ506G2.1, MRX12, MRX35, THO2 ENSG00000125676 THO complex 2 X 123600561-123733056 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047921 Supported Approved Nucleoplasm Expressed in all epididymis: 45.9 -MED1 CRSP1, CRSP200, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2 ENSG00000125686 Mediator complex subunit 1 17 39404285-39451286 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017696, HPA052818 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 56.9 -RPL23 L23, rpL17 ENSG00000125691 Ribosomal protein L23 17 38847865-38853843 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003373 Approved Supported Cytosol Expressed in all ovary: 4483.4 -ATG4C APG4C, AUTL1, AUTL3, FLJ14867 ENSG00000125703 Autophagy related 4C, cysteine peptidase 1 62784135-62865513 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007049 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 23.6 -CD70 CD27L, CD27LG, TNFSF7 ENSG00000125726 CD70 molecule 19 6583183-6604103 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046582 Uncertain Nucleoplasm Tissue enhanced 0 appendix: 4.5 lymph node: 3.9 -C3 ARMD9, C3a, C3b, CPAMD1 ENSG00000125730 Complement component 3 19 6677704-6730562 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003563, CAB004209, HPA020432 Supported Expressed in all liver: 2484.3 -SH2D3A NSP1 ENSG00000125731 SH2 domain containing 3A 19 6752160-6767588 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035722, HPA064382 Uncertain Approved Nucleoplasm
Microtubules
Cytokinetic bridge Mixed duodenum: 14.2 -TRIP10 CIP4, HSTP, STOT, STP ENSG00000125733 Thyroid hormone receptor interactor 10 19 6737925-6751526 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041934 Supported Nucleoplasm
Vesicles Expressed in all skeletal muscle: 129.1 -GPR108 LUSTR2 ENSG00000125734 G protein-coupled receptor 108 19 6729914-6737603 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041924, HPA041951, HPA063863 Uncertain Supported Golgi apparatus
Vesicles Expressed in all parathyroid gland: 73.7 -TNFSF14 CD258, HVEM-L, LIGHT, LTg ENSG00000125735 Tumor necrosis factor (ligand) superfamily, member 14 19 6661253-6670588 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012700 Approved Mixed adipose tissue: 6.8 -FOSB AP-1, DKFZp686C0818, G0S3, GOS3, GOSB, MGC42291 ENSG00000125740 FBJ murine osteosarcoma viral oncogene homolog B 19 45467995-45475179 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB010267, HPA054663 Approved Supported Nucleoplasm
Vesicles Mixed gallbladder: 560.0 -OPA3 FLJ22187, MGA3 ENSG00000125741 Optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 19 45527427-45602212 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044881 Uncertain Approved Nucleoplasm
Cytosol Mixed parathyroid gland: 18.0 -SNRPD2 Sm-D2, SNRPD1 ENSG00000125743 Small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 19 45687454-45692569 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041437 Supported Uncertain Cytosol Expressed in all ovary: 334.1 -RTN2 NSP2, NSPL1, SPG12 ENSG00000125744 Reticulon 2 19 45485289-45497061 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034941, HPA034948 Approved Approved Nuclear speckles Tissue enriched 6 skeletal muscle: 175.3 placenta: 27.3 -EML2 ELP70, EMAP-2, EMAP2 ENSG00000125746 Echinoderm microtubule associated protein like 2 19 45606994-45645629 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012757 Approved Approved Vesicles Expressed in all parathyroid gland: 98.7 -VASP ENSG00000125753 Vasodilator-stimulated phosphoprotein 19 45506579-45526983 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004612, HPA005724 Supported Supported Plasma membrane
Cell Junctions
Focal adhesion sites Expressed in all appendix: 93.1 -SYMPK SPK, SYM ENSG00000125755 Symplekin 19 45815410-45863290 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041756, HPA042449 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 74.6 -GPCPD1 GDE5, GDPD6, KIAA1434 ENSG00000125772 Glycerophosphocholine phosphodiesterase 1 20 5544404-5611026 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039556, HPA042987 Uncertain Approved Nucleoplasm Expressed in all bone marrow: 46.6 -SDCBP2 SITAC18, ST-2 ENSG00000125775 Syndecan binding protein (syntenin) 2 20 1309909-1329239 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054554 Approved Vesicles
Cytosol Tissue enhanced 0 duodenum: 138.8;small intestine: 146.8 stomach: 96.4 -PANK2 C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN ENSG00000125779 Pantothenate kinase 2 20 3888839-3929882 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008440 Approved Supported Cytosol Expressed in all testis: 51.6 -TGM3 TGE ENSG00000125780 Transglutaminase 3 20 2296001-2341078 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004728 Approved Tissue enriched 12 esophagus: 1519.7 tonsil: 131.7 -GNRH2 ENSG00000125787 Gonadotropin-releasing hormone 2 20 3043622-3045747 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA004338 Uncertain Mixed ovary: 2.6 -DEFB126 bA530N10.1, C20orf8, DEFB-26 ENSG00000125788 Defensin, beta 126 20 142369-145751 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 233 epididymis: 653.9 seminal vesicle: 2.8 -FOXA2 HNF3B ENSG00000125798 Forkhead box A2 20 22581005-22585455 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001388, HPA066846 Approved Supported Nucleoplasm
Cell Junctions Tissue enhanced 0 cervix, uterine: 21.3;lung: 20.6;stomach: 31.3 liver: 11.5 -CD93 C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4 ENSG00000125810 CD93 molecule 20 23079349-23086340 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009300, HPA012368 Supported Approved Vesicles
Plasma membrane Expressed in all placenta: 195.4 -GZF1 dJ322G13.2, ZBTB23, ZNF336 ENSG00000125812 GDNF-inducible zinc finger protein 1 20 23362182-23373063 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024520 Uncertain Supported Nucleus
Nucleoli Expressed in all adrenal gland: 25.5 -PAX1 ENSG00000125813 Paired box 1 20 21705659-21718486 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 10 parathyroid gland: 182.0 tonsil: 18.2 -NAPB SNAP-BETA, SNAPB ENSG00000125814 N-ethylmaleimide-sensitive factor attachment protein, beta 20 23374519-23421519 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037225, CAB037227, HPA046149, HPA050196 Approved Uncertain Cytosol Tissue enriched 9 cerebral cortex: 304.1 adrenal gland: 32.3 -CST8 CRES, CTES5 ENSG00000125815 Cystatin 8 (cystatin-related epididymal specific) 20 23491101-23496018 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 207 testis: 20.6 epididymis: 0.0 -NKX2-4 NKX2.4, NKX2D ENSG00000125816 NK2 homeobox 4 20 21395367-21398028 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA074996 Approved Nuclear bodies Tissue enriched 10 testis: 2.2 epididymis: 0.2 -CENPB ENSG00000125817 Centromere protein B, 80kDa 20 3783851-3786690 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011626, HPA053507, HPA054405 Approved Validated Nuclear bodies Expressed in all skin: 43.5 -PSMF1 PI31 ENSG00000125818 Proteasome inhibitor subunit 1 20 1113263-1189415 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041122, HPA041300 Approved Validated Cytosol Expressed in all testis: 135.7 -NKX2-2 NKX2.2, NKX2B ENSG00000125820 NK2 homeobox 2 20 21511010-21514026 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA003468 Approved Tissue enhanced 0 cerebral cortex: 10.0;stomach: 2.6 duodenum: 2.4 -DTD1 bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, MGC119131, MGC41905, pqn-68 ENSG00000125821 D-tyrosyl-tRNA deacylase 1 20 18567453-18763917 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040981, HPA042653 Uncertain Uncertain Nucleoli
Cytosol Expressed in all cerebral cortex: 55.9 -CSTL1 CTES1, dJ322G13.4 ENSG00000125823 Cystatin-like 1 20 23439685-23444930 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 37 testis: 4.6 seminal vesicle: 0.1 -RBCK1 C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4 ENSG00000125826 RanBP-type and C3HC4-type zinc finger containing 1 20 407498-430966 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024185 Uncertain Expressed in all spleen: 49.1 -TMX4 DJ971N18.2, KIAA1162, PDIA14, TXNDC13 ENSG00000125827 Thioredoxin-related transmembrane protein 4 20 7977348-8019829 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000399, HPA015752 Supported Supported Nuclear membrane Expressed in all testis: 117.9 -CST11 CST8L, CTES2, dJ322G13.6 ENSG00000125831 Cystatin 11 20 23450403-23452857 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA053399 Supported Tissue enriched 207 epididymis: 261.5 testis: 1.2 -STK35 bA550O8.2, CLIK1 ENSG00000125834 Serine/threonine kinase 35 20 2101611-2177038 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA026452, HPA051673 Uncertain Supported Nucleus
Nuclear bodies Expressed in all testis: 25.2 -SNRPB COD, Sm-B/B', SmB/SmB', snRNP-B, SNRPB1 ENSG00000125835 Small nuclear ribonucleoprotein polypeptides B and B1 20 2461634-2470853 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003482, CAB009610, HPA067842 Approved Supported Nucleoplasm Expressed in all bone marrow: 202.5 -NRSN2 C20orf98, dJ1103G7.6 ENSG00000125841 Neurensin 2 20 346782-359660 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015967 Approved Approved Nucleoplasm
Vesicles
Cytosol Tissue enhanced 0 cerebral cortex: 126.5 parathyroid gland: 68.4 -AP5S1 C20orf29, FLJ11168 ENSG00000125843 Adaptor-related protein complex 5, sigma 1 subunit 20 3820524-3828837 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034200, HPA048244 Uncertain Approved Nucleoplasm
Cytosol Expressed in all testis: 12.5 -RRBP1 ES/130, hES ENSG00000125844 Ribosome binding protein 1 20 17613678-17682295 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009026, HPA011924 Supported Validated Endoplasmic reticulum Expressed in all thyroid gland: 219.5 -BMP2 BMP2A ENSG00000125845 Bone morphogenetic protein 2 20 6767664-6780280 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA058610 Supported Vesicles Mixed thyroid gland: 31.1 -ZNF133 pHZ-13, pHZ-66, ZNF150 ENSG00000125846 Zinc finger protein 133 20 18288283-18316996 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001493 Supported Approved Nucleus
Vesicles Expressed in all epididymis: 19.7 -FLRT3 ENSG00000125848 Fibronectin leucine rich transmembrane protein 3 20 14322988-14337616 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026166, HPA056033 Supported Approved Plasma membrane
Microtubules
Cytosol Mixed lung: 32.3 -OVOL2 bA504H3.3, HOVO2, ZNF339 ENSG00000125850 Ovo-like zinc finger 2 20 17956979-18059188 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA038531 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 stomach: 8.2 colon: 3.6 -PCSK2 NEC2, PC2, SPC2 ENSG00000125851 Proprotein convertase subtilisin/kexin type 2 20 17226107-17484578 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049627 Approved Approved Vesicles Tissue enhanced 0 adrenal gland: 37.7;cerebral cortex: 31.8 skin: 16.5 -GFRA4 ENSG00000125861 GDNF family receptor alpha 4 20 3659292-3663399 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 thyroid gland: 1.4 testis: 0.3 -MKKS BBS6 ENSG00000125863 McKusick-Kaufman syndrome 20 10401009-10434222 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041071, HPA044233 Supported Supported Centrosome Expressed in all testis: 43.5 -BFSP1 CP115, CP94, filensin, LIFL-H ENSG00000125864 Beaded filament structural protein 1, filensin 20 17493905-17569220 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040748, HPA042038 Supported Supported Plasma membrane
Cytosol Mixed testis: 6.5 -DSTN ACTDP, ADF ENSG00000125868 Destrin (actin depolymerizing factor) 20 17569863-17609919 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037094 Approved Expressed in all seminal vesicle: 1044.5 -LAMP5 BAD-LAMP, C20orf103, dJ1119D9.3, UNC-43 ENSG00000125869 Lysosomal-associated membrane protein family, member 5 20 9514358-9530524 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004802, HPA070765 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 45.0;ovary: 24.5 fallopian tube: 14.8 -SNRPB2 Msl1 ENSG00000125870 Small nuclear ribonucleoprotein polypeptide B 20 16729961-16742563 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050814 Supported Nuclear speckles Expressed in all lymph node: 50.5 -MGME1 bA504H3.4, C20orf72, DDK1 ENSG00000125871 Mitochondrial genome maintenance exonuclease 1 20 17968913-17991122 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040913 Approved Supported Mitochondria Expressed in all skin: 39.8 -LRRN4 C20orf75, dJ1056H1.1, NLRR4 ENSG00000125872 Leucine rich repeat neuronal 4 20 6040778-6054049 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA075974 Approved Nucleus
Nucleoli
Cytosol Tissue enriched 11 lung: 13.6 fallopian tube: 1.3 -TBC1D20 C20orf140, dJ852M4.2 ENSG00000125875 TBC1 domain family, member 20 20 435480-462553 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043613 Approved Expressed in all parathyroid gland: 30.7 -ITPA C20orf37, dJ794I6.3, HLC14-06-P ENSG00000125877 Inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 20 3208868-3223870 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022824 Approved Supported Cytosol Expressed in all fallopian tube: 39.5 -TCF15 bHLHa40, EC2, PARAXIS ENSG00000125878 Transcription factor 15 (basic helix-loop-helix) 20 603797-610398 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA050998, HPA060221 Uncertain Supported Nuclear speckles Group enriched 5 adipose tissue: 9.0;heart muscle: 5.5;placenta: 8.0;skeletal muscle: 7.2;testis: 2.2 lung: 1.2 -OTOR FDP, MIAL, MIAL1 ENSG00000125879 Otoraplin 20 16748358-16770062 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA024335 Uncertain Not detected epididymis: 0.0 -MCM8 C20orf154, dJ967N21.5, MGC119522, MGC119523, MGC12866, MGC4816, REC ENSG00000125885 Minichromosome maintenance 8 homologous recombination repair factor 20 5950652-5998977 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045141 Supported Nucleus Tissue enhanced 0 testis: 27.6 lymph node: 10.4 -BANF2 BAF-L, BAF2, BAFL, C20orf179, dJ803K15.1 ENSG00000125888 Barrier to autointegration factor 2 20 17693672-17735871 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042635 Approved Tissue enriched 29 testis: 123.9 pancreas: 4.3 -TMEM74B C20orf46, FLJ11190 ENSG00000125895 Transmembrane protein 74B 20 1180561-1185415 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045213 Approved Approved Nucleoplasm
Golgi apparatus Mixed small intestine: 28.0 -FAM110A bA371L19.3, C20orf55 ENSG00000125898 Family with sequence similarity 110, member A 20 833715-857463 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034110, HPA069240 Uncertain Supported Nucleus
Vesicles
Cytosol Tissue enhanced 0 skin: 31.4 spleen: 21.8 -SIRPD dJ576H24.4, PTPNS1L2 ENSG00000125900 Signal-regulatory protein delta 20 1534251-1558843 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042663 Supported Tissue enriched 18 testis: 72.3 appendix: 4.0 -MRPS26 C20orf193, dJ534B8.3, MRP-S13, MRP-S26, RPMS13 ENSG00000125901 Mitochondrial ribosomal protein S26 20 3045945-3048254 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045472, HPA054610 Supported Validated Mitochondria Expressed in all prostate: 49.1 -DEFB129 bA530N10.3, C20orf87, DEFB-29 ENSG00000125903 Defensin, beta 129 20 227258-229886 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 492 epididymis: 2327.0 seminal vesicle: 4.7 -S1PR4 EDG6 ENSG00000125910 Sphingosine-1-phosphate receptor 4 19 3172346-3180332 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060601, HPA067232 Uncertain Mitochondria Tissue enhanced 0 lymph node: 18.3;spleen: 27.0 appendix: 14.5 -NCLN NET59, NICALIN ENSG00000125912 Nicalin 19 3185563-3209575 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006625 Approved Uncertain Nucleoplasm
Lipid droplets Expressed in all duodenum: 34.8 -CITED1 MSG1 ENSG00000125931 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 X 72301638-72307187 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049051 Supported Nucleoplasm
Cytosol Tissue enriched 7 epididymis: 1767.1 testis: 257.8 -HNRNPR hnRNP-R, HNRPR ENSG00000125944 Heterogeneous nuclear ribonucleoprotein R 1 23303771-23344336 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011687, HPA026092 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 65.7 -ZNF436 KIAA1710, Zfp46 ENSG00000125945 Zinc finger protein 436 1 23359448-23369442 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043817 Approved Supported Nucleoplasm
Cytosol Mixed ovary: 12.4 -MAX bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8 ENSG00000125952 MYC associated factor X 14 65006174-65102695 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000328, HPA003474 Supported Supported Nucleoplasm
Golgi apparatus
Vesicles Expressed in all spleen: 80.2 -CHURC1-FNTB ENSG00000125954 CHURC1-FNTB readthrough 14 64914485-65061803 Predicted intracellular proteins Evidence at protein level Evidence at protein level CAB009260 Uncertain Mixed adipose tissue: 1.5 -ARMCX5 FLJ12969, GASP5 ENSG00000125962 Armadillo repeat containing, X-linked 5 X 102599168-102604159 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000996 Approved Approved Nuclear speckles
Cytosol Expressed in all thyroid gland: 32.6 -GDF5 BMP14, CDMP1 ENSG00000125965 Growth differentiation factor 5 20 35433347-35454746 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA015648 Uncertain Tissue enhanced 0 salivary gland: 4.1 seminal vesicle: 1.7 -MMP24 MT5-MMP ENSG00000125966 Matrix metallopeptidase 24 (membrane-inserted) 20 35226654-35277000 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049280 Approved Nucleoli
Plasma membrane Tissue enhanced 0 cerebral cortex: 10.6 lung: 7.1 -NECAB3 APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, NIP1, SYTIP2, XB51 ENSG00000125967 N-terminal EF-hand calcium binding protein 3 20 33657087-33674463 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044785 Supported Golgi apparatus Mixed prostate: 31.7 -ID1 bHLHb24, dJ857M17.1.2 ENSG00000125968 Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 20 31605283-31606515 Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025915, HPA051456, HPA058518 Approved Validated Nucleoplasm
Golgi apparatus Expressed in all seminal vesicle: 211.5 -RALY HNRPCL2, P542 ENSG00000125970 RALY heterogeneous nuclear ribonucleoprotein 20 33993646-34108308 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040971, HPA043614 Supported Validated Nucleoplasm Expressed in all testis: 140.7 -DYNLRB1 DNCL2A, DNLC2A, ROBLD1 ENSG00000125971 Dynein, light chain, roadblock-type 1 20 34516409-34540958 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009845 Approved Expressed in all cerebral cortex: 341.9 -C20orf173 dJ477O4.4 ENSG00000125975 Chromosome 20 open reading frame 173 20 35523186-35529652 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 137 testis: 34.3 skin: 0.2 -EIF2S2 EIF2, EIF2beta, PPP1R67 ENSG00000125977 Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 20 34088298-34112332 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034415, HPA041262, HPA041332 Approved Supported Nucleoli
Endoplasmic reticulum Expressed in all placenta: 74.0 -ERGIC3 C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84 ENSG00000125991 ERGIC and golgi 3 20 35542021-35557634 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015242, HPA015968 Approved Supported Nucleoplasm Expressed in all epididymis: 520.8 -ROMO1 bA353C18.2, C20orf52, MTGMP ENSG00000125995 Reactive oxygen species modulator 1 20 35699272-35700984 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012782 Uncertain Expressed in all adrenal gland: 121.3 -FAM83C C20orf128, dJ614O4.7 ENSG00000125998 Family with sequence similarity 83, member C 20 35285731-35292401 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB034227, HPA049978 Uncertain Group enriched 15 esophagus: 19.9;skin: 43.2 tonsil: 2.0 -BPIFB1 bA49G10.6, C20orf114, dJ1187J4.1, LPLUNC1, MGC14597, VEMSGP ENSG00000125999 BPI fold containing family B, member 1 20 33273480-33309878 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024256 Supported Tissue enhanced 0 cervix, uterine: 833.9;stomach: 459.3 lung: 158.1 -CEP250 C-NAP1, CEP2 ENSG00000126001 Centrosomal protein 250kDa 20 35455164-35519280 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064875 Supported Centrosome Expressed in all testis: 35.1 -PLAGL2 ZNF900 ENSG00000126003 Pleiomorphic adenoma gene-like 2 20 32192503-32207791 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA005900 Uncertain Approved Nucleoplasm
Cytosol Expressed in all testis: 25.7 -MMP24-AS1 ENSG00000126005 MMP24 antisense RNA 1 20 35201745-35278131 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Expressed in all adipose tissue: 46.8 -GRPR BB2 ENSG00000126010 Gastrin-releasing peptide receptor X 16123556-16153021 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA069604 Validated Plasma membrane Tissue enhanced 0 pancreas: 4.2 breast: 2.6 -KDM5C DXS1272E, JARID1C, MRX13, SMCX, XE169 ENSG00000126012 Lysine (K)-specific demethylase 5C X 53191321-53225422 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038244, HPA046147 Validated Nucleoplasm
Cytosol Expressed in all parathyroid gland: 65.5 -AMOT KIAA1071 ENSG00000126016 Angiomotin X 112774503-112840815 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067290 Supported Tissue enhanced 0 epididymis: 175.1 seminal vesicle: 38.2 -TMEM115 PL6 ENSG00000126062 Transmembrane protein 115 3 50354749-50359610 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006319, HPA015497 Supported Supported Golgi apparatus Expressed in all parathyroid gland: 36.8 -PSMB2 HC7-I ENSG00000126067 Proteasome subunit beta 2 1 35599544-35641844 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026322, HPA026324 Approved Validated Nucleoplasm Expressed in all placenta: 43.0 -AGO3 EIF2C3, FLJ12765, hAGO3 ENSG00000126070 Argonaute RISC catalytic component 3 1 35930718-36072500 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048342, HPA075436 Uncertain Supported Nucleoplasm
Cytoplasmic bodies Mixed testis: 10.3 -UROD ENSG00000126088 Uroporphyrinogen decarboxylase 1 45012147-45015575 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027468, HPA028668, HPA030350 Uncertain Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 113.1 -ST3GAL3 MRT12, SIAT6 ENSG00000126091 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 1 43705824-43931165 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051102 Uncertain Expressed in all skeletal muscle: 30.5 -TMEM53 FLJ22353, NET4 ENSG00000126106 Transmembrane protein 53 1 44635238-44674555 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021134 Approved Approved Golgi apparatus
Focal adhesion sites Mixed testis: 23.3 -HECTD3 FLJ21156 ENSG00000126107 HECT domain containing E3 ubiquitin protein ligase 3 1 45002540-45011329 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027467 Approved Expressed in all duodenum: 48.6 -KLC1 hKLC1B, hKLC1G, hKLC1J, hKLC1N, hKLC1P, hKLC1R, hKLC1S, KLC, KNS2, KNS2A ENSG00000126214 Kinesin light chain 1 14 103561896-103714249 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009798, HPA044617, HPA052450 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Expressed in all cerebral cortex: 469.3 -XRCC3 ENSG00000126215 X-ray repair complementing defective repair in Chinese hamster cells 3 14 103697609-103715504 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062422, HPA068953 Validated Nucleus Expressed in all skin: 46.0 -TUBGCP3 GCP3, SPBC98, Spc98p ENSG00000126216 Tubulin, gamma complex associated protein 3 13 112485005-112588167 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043913 Approved Expressed in all testis: 33.1 -MCF2L ARHGEF14, DBS, KIAA0362, OST ENSG00000126217 MCF.2 cell line derived transforming sequence-like 13 112894378-113099739 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 62.6 -F10 ENSG00000126218 Coagulation factor X 13 113122814-113149529 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 liver: 68.0 cervix: 51.6 -PCID2 FLJ11305 ENSG00000126226 PCI domain containing 2 13 113177539-113208715 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069107, HPA073074 Uncertain Approved Nucleus
Nucleoli Expressed in all testis: 81.5 -PROZ PZ ENSG00000126231 Protein Z, vitamin K-dependent plasma glycoprotein 13 113158654-113172383 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052006 Approved Group enriched 13 kidney: 14.5;liver: 27.4 testis: 1.6 -SLURP1 ANUP, ARS, ArsB, LY6LS, MDM ENSG00000126233 Secreted LY6/PLAUR domain containing 1 8 142740944-142742411 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050967 Approved Group enriched 32 esophagus: 743.9;skin: 296.7 tonsil: 16.4 -LRFN3 FIGLER1, MGC2656, SALM4 ENSG00000126243 Leucine rich repeat and fibronectin type III domain containing 3 19 35935358-35945767 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048923 Approved Mixed cerebral cortex: 8.2 -IGFLR1 FLJ22573, TMEM149, U2AF1L4 ENSG00000126246 IGF-like family receptor 1 19 35738801-35742453 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012369 Uncertain Approved Focal adhesion sites Mixed lymph node: 38.0 -CAPNS1 30K, CANP, CANPS, CAPN4, CDPS ENSG00000126247 Calpain, small subunit 1 19 36139575-36150353 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006872 Approved Approved Nucleoplasm
Cytosol Expressed in all esophagus: 517.3 -PDCD2L MGC13096 ENSG00000126249 Programmed cell death 2-like 19 34404384-34426168 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052181 Approved Uncertain Mitochondria Mixed testis: 17.6 -GPR42 FFAR3L, GPR41L, GPR42P ENSG00000126251 G protein-coupled receptor 42 (gene/pseudogene) 19 35370929-35372962 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level HPA044681 Uncertain Not detected small intestine: 0.3 -RBM42 MGC10433 ENSG00000126254 RNA binding motif protein 42 19 35629030-35637686 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043671 Supported Approved Nucleus
Cytosol Expressed in all spleen: 39.5 -KIRREL2 DKFZp564A1164, FILTRIN, MGC15718, NEPH3, NLG1 ENSG00000126259 Kin of IRRE like 2 (Drosophila) 19 35855861-35867109 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041170 Approved Vesicles Tissue enriched 8 pancreas: 11.6 cerebral cortex: 1.4 -UBA2 ARX, FLJ13058, HRIHFB2115, SAE2 ENSG00000126261 Ubiquitin-like modifier activating enzyme 2 19 34428352-34471251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041436 Supported Supported Nucleoplasm Expressed in all testis: 167.2 -FFAR2 FFA2R, GPR43 ENSG00000126262 Free fatty acid receptor 2 19 35443907-35451767 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA023985 Approved Tissue enhanced 0 appendix: 26.2;bone marrow: 13.4 spleen: 11.1 -HCST DAP10, DKFZP586C1522, KAP10, PIK3AP ENSG00000126264 Hematopoietic cell signal transducer 19 35902480-35904377 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB034435, HPA063026 Supported Uncertain Vesicles Expressed in all bone marrow: 154.7 -FFAR1 FFA1R, GPR40 ENSG00000126266 Free fatty acid receptor 1 19 35351552-35353862 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 bone marrow: 1.9 ovary: 1.2 -COX6B1 COX6B, COXG ENSG00000126267 Cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 19 35648223-35658861 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004192 Supported Supported Mitochondria Expressed in all heart muscle: 466.9 -KRT36 KRTHA6 ENSG00000126337 Keratin 36, type I 17 41486136-41492546 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 2.1;tonsil: 1.6 spleen: 0.5 -THRA AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3 ENSG00000126351 Thyroid hormone receptor, alpha 17 40058290-40093867 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009654, CAB023349 Uncertain Supported Cytosol Expressed in all cerebral cortex: 239.6 -CCR7 BLR2, CD197, CDw197, CMKBR7, EBI1 ENSG00000126353 Chemokine (C-C motif) receptor 7 17 40553769-40565472 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB003796, HPA031383, HPA074467 Supported Supported Mitochondria Group enriched 6 appendix: 91.9;lymph node: 98.3;spleen: 39.9;tonsil: 80.2 urinary bladder: 12.9 -NR1D1 ear-1, hRev, Rev-ErbAalpha, THRA1, THRAL ENSG00000126368 Nuclear receptor subfamily 1, group D, member 1 17 40092787-40100725 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA007935 Uncertain Supported Nuclear bodies Mixed cerebral cortex: 37.5 -FRMD8 FKSG44, FLJ90369 ENSG00000126391 FERM domain containing 8 11 65386599-65413525 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002861, HPA005506 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all skin: 25.0 -PRDX5 ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10 ENSG00000126432 Peroxiredoxin 5 11 64318088-64321811 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008661, HPA037915, HPA037916 Supported Validated Mitochondria
Cytosol Expressed in all fallopian tube: 599.3 -BCL2L12 ENSG00000126453 BCL2-like 12 (proline rich) 19 49665142-49673916 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020856 Approved Approved Cytosol Expressed in all lymph node: 25.0 -IRF3 ENSG00000126456 Interferon regulatory factor 3 19 49659569-49665875 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004895, CAB013018 Approved Supported Cytosol Expressed in all lymph node: 47.9 -PRMT1 ANM1, HCP1, HRMT1L2 ENSG00000126457 Protein arginine methyltransferase 1 19 49675786-49689029 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022550, HPA069769, HPA072136 Supported Supported Nucleoplasm Expressed in all fallopian tube: 178.9 -RRAS ENSG00000126458 Related RAS viral (r-ras) oncogene homolog 19 49635292-49640201 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010160, HPA060364, CAB069439 Uncertain Approved Vesicles Expressed in all seminal vesicle: 206.9 -PRRG2 PRGP2 ENSG00000126460 Proline rich Gla (G-carboxyglutamic acid) 2 19 49580646-49591015 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA010702 Approved Approved Nucleus
Nucleoli
Cytosol Mixed parathyroid gland: 28.8 -SCAF1 FLJ00034, SR-A1 ENSG00000126461 SR-related CTD-associated factor 1 19 49642125-49658642 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046828, HPA054593 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 51.8 -PRR12 KIAA1205 ENSG00000126464 Proline rich 12 19 49591643-49626439 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011959 Approved Approved Cytosol Mixed skin: 15.3 -TSKS PPP1R161, TSSKS ENSG00000126467 Testis-specific serine kinase substrate 19 49739753-49763330 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045729 Approved Tissue enriched 43 testis: 72.5 skin: 1.6 -FLRT1 MGC21624, SPG68 ENSG00000126500 Fibronectin leucine rich transmembrane protein 1 11 64103188-64119173 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054589 Uncertain Tissue enhanced 0 cerebral cortex: 12.5 adrenal gland: 5.9 -ASL ENSG00000126522 Argininosuccinate lyase 7 66075798-66093558 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003696, HPA016646 Supported Approved Cytosol Expressed in all liver: 97.4 -SBDS CGI-97, FLJ10917, SDS, SWDS ENSG00000126524 Shwachman-Bodian-Diamond syndrome 7 66987677-66995601 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028891 Approved Supported Nucleus
Cytosol Expressed in all parathyroid gland: 238.7 -CSN1S1 CASA, CSN1 ENSG00000126545 Casein alpha s1 4 69931081-69946574 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035659, HPA057031 Supported Tissue enriched 85 breast: 1608.6 adipose tissue: 18.9 -STATH STR ENSG00000126549 Statherin 4 69995930-70002570 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044569 Supported Tissue enriched 1726 salivary gland: 45012.6 ovary: 26.0 -HTN1 HIS1 ENSG00000126550 Histatin 1 4 70050402-70058845 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 1790 salivary gland: 24450.0 ovary: 13.6 -STAT5A MGF, STAT5 ENSG00000126561 Signal transducer and activator of transcription 5A 17 42287547-42311943 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003860, HPA027873, HPA042128, HPA049883, HPA051156 Approved Validated Nucleoplasm
Cytosol Expressed in all adipose tissue: 90.2 -WNK4 PRKWNK4 ENSG00000126562 WNK lysine deficient protein kinase 4 17 42780678-42796936 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016500 Approved Tissue enhanced 0 kidney: 18.9;prostate: 14.3;rectum: 12.1 colon: 8.9 -BECN1 ATG6, VPS30 ENSG00000126581 Beclin 1, autophagy related 17 42810134-42833350 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010143, HPA028949 Supported Approved Centrosome Expressed in all rectum: 71.6 -PRKCG MGC57564, PKCC, PKCG, SCA14 ENSG00000126583 Protein kinase C, gamma 19 53879190-53907652 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013051, HPA047870, HPA054560 Supported Tissue enriched 9 cerebral cortex: 41.1 testis: 4.7 -TRAP1 HSP75, HSP90L ENSG00000126602 TNF receptor-associated protein 1 16 3651639-3717597 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041082, HPA044227 Supported Validated Mitochondria Expressed in all fallopian tube: 94.4 -GLIS2 NPHP7 ENSG00000126603 GLIS family zinc finger 2 16 4314761-4339597 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA056976 Approved Nucleoplasm
Plasma membrane
Cytosol Mixed gallbladder: 9.7 -NSRP1 CCDC55, DKFZP434K1421, NSrp70 ENSG00000126653 Nuclear speckle splicing regulatory protein 1 17 30115521-30186475 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015593, HPA015603 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 45.1 -DNAJC8 SPF31 ENSG00000126698 DnaJ (Hsp40) homolog, subfamily C, member 8 1 28199456-28233025 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026275, HPA026283 Approved Validated Nucleoplasm Expressed in all lymph node: 94.7 -AHDC1 DJ159A19.3, RP1-159A19.1 ENSG00000126705 AT hook, DNA binding motif, containing 1 1 27534035-27604431 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028648, HPA028691 Approved Supported Nucleus Mixed spleen: 16.3 -IFI6 6-16, FAM14C, G1P3, IFI-6-16, IFI616 ENSG00000126709 Interferon, alpha-inducible protein 6 1 27666061-27672218 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA005543 Approved Approved Mitochondria Expressed in all placenta: 412.1 -DACH2 ENSG00000126733 Dachshund family transcription factor 2 X 86148458-86832604 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000258 Uncertain Group enriched 8 cerebral cortex: 11.9;epididymis: 4.4;fallopian tube: 5.0 kidney: 0.8 -ZNF384 CAGH1A, CIZ, NMP4, NP, TNRC1 ENSG00000126746 Zinc finger protein 384 12 6666477-6689572 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004051 Supported Supported Nucleoplasm Expressed in all endometrium: 65.7 -EMG1 C2F, Grcc2f, NEP1 ENSG00000126749 EMG1 N1-specific pseudouridine methyltransferase 12 6970893-6979941 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039304, HPA039666 Supported Validated Nucleus
Nucleoli Expressed in all appendix: 21.6 -SSX1 CT5.1 ENSG00000126752 Synovial sarcoma, X breakpoint 1 X 48255317-48267444 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045683 Supported Approved Nucleus
Nucleoli Tissue enriched 32 testis: 12.7 thyroid gland: 0.3 -UXT ART-27, STAP1 ENSG00000126756 Ubiquitously-expressed, prefoldin-like chaperone X 47651798-47659161 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050499, HPA058400 Approved Supported Nucleus
Microtubule organizing center
Cytosol Expressed in all ovary: 183.7 -CFP PFC ENSG00000126759 Complement factor properdin X 47624213-47630305 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 58.2;spleen: 78.3 appendix: 31.0 -ELK1 ENSG00000126767 ELK1, member of ETS oncogene family X 47635521-47650604 Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003808, HPA036084, HPA064381 Supported Validated Nucleoplasm Expressed in all ovary: 50.8 -TIMM17B DXS9822, JM3 ENSG00000126768 Translocase of inner mitochondrial membrane 17 homolog B (yeast) X 48893447-48898143 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029093 Approved Approved Microtubules
Mitochondria Expressed in all fallopian tube: 43.4 -PCNXL4 C14orf135 ENSG00000126773 Pecanex-like 4 (Drosophila) 14 60091911-60169133 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA002076, HPA003390 Uncertain Approved Cytosol Expressed in all parathyroid gland: 31.6 -ATG14 ATG14L, KIAA0831 ENSG00000126775 Autophagy related 14 14 55366392-55411858 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB037242 Uncertain Expressed in all bone marrow: 17.2 -KTN1 CG1, KIAA0004 ENSG00000126777 Kinectin 1 (kinesin receptor) 14 55559072-55701526 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003178, CAB015331, HPA017876 Supported Validated Endoplasmic reticulum Expressed in all testis: 269.6 -SIX1 DFNA23 ENSG00000126778 SIX homeobox 1 14 60643415-60658259 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001893, CAB058690 Supported Supported Nucleus
Nucleoli Group enriched 6 cervix, uterine: 23.0;parathyroid gland: 57.4;prostate: 21.5;salivary gland: 21.7;skeletal muscle: 41.5 adipose tissue: 5.7 -RHOJ ARHJ, FLJ14445, RASL7B, TCL ENSG00000126785 Ras homolog family member J 14 63204114-63293219 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003050 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Mixed endometrium: 47.9 -DLGAP5 DLG1, DLG7, HURP, KIAA0008 ENSG00000126787 Discs, large (Drosophila) homolog-associated protein 5 14 55148112-55191678 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005546 Approved Supported Microtubule organizing center
Cytosol Tissue enhanced 0 testis: 29.6 lymph node: 20.7 -L3HYPDH C14orf149, FLJ25436 ENSG00000126790 L-3-hydroxyproline dehydratase (trans-) 14 59460363-59484430 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056694 Approved Uncertain Vesicles Expressed in all testis: 31.9 -HSPA2 ENSG00000126803 Heat shock 70kDa protein 2 14 64535905-64546173 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000798, HPA052504 Approved Approved Uncertain Nucleoplasm
Vesicles Tissue enhanced 0 testis: 188.7 cerebral cortex: 96.7 -ZBTB1 KIAA0997, ZNF909 ENSG00000126804 Zinc finger and BTB domain containing 1 14 64503712-64533690 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050516 Approved Supported Nucleoplasm
Nuclear membrane Expressed in all bone marrow: 53.6 -TRMT5 KIAA1393, TRM5 ENSG00000126814 TRNA methyltransferase 5 14 60971451-60981358 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000943 Supported Approved Nucleus
Nucleoli Expressed in all testis: 31.1 -SGPP1 ENSG00000126821 Sphingosine-1-phosphate phosphatase 1 14 63684214-63728039 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053149, HPA064908 Approved Supported Nucleus Expressed in all placenta: 34.5 -PLEKHG3 ARHGEF43, KIAA0599 ENSG00000126822 Pleckstrin homology domain containing, family G (with RhoGef domain) member 3 14 64704102-64750247 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063455, HPA065323 Supported Nucleoplasm
Plasma membrane
Cytokinetic bridge
Centrosome
Cytosol Expressed in all seminal vesicle: 52.5 -PZP CPAMD6 ENSG00000126838 Pregnancy-zone protein 12 9148840-9208370 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041403, HPA041471 Supported Tissue enriched 12 liver: 46.1 testis: 3.8 -PRDM7 ZNF910 ENSG00000126856 PR domain containing 7 16 90056566-90092072 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059944 Approved Uncertain Nuclear speckles Tissue enriched 6 testis: 1.0 epididymis: 0.1 -RHOT1 ARHT1, FLJ11040, MIRO-1 ENSG00000126858 Ras homolog family member T1 17 32142454-32253374 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010687, CAB068223, CAB068224 Supported Expressed in all parathyroid gland: 47.9 -EVI2A EVDA, EVI2 ENSG00000126860 Ecotropic viral integration site 2A 17 31317560-31321884 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045033, HPA057051 Uncertain Approved Nucleoplasm
Nuclear bodies Mixed cerebral cortex: 83.2 -OMG OMGP ENSG00000126861 Oligodendrocyte myelin glycoprotein 17 31272013-31297539 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008206, HPA012693 Supported Tissue enriched 318 cerebral cortex: 137.8 bone marrow: 0.4 -WDR60 FAP163, FLJ10300 ENSG00000126870 WD repeat domain 60 7 158856578-158956747 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020607, HPA021316 Approved Approved Microtubule organizing center Expressed in all testis: 75.4 -AIF1L C9orf58, FLJ12783, IBA2 ENSG00000126878 Allograft inflammatory factor 1-like 9 131096476-131123152 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020522, HPA056852 Supported Tissue enhanced 0 kidney: 286.8;spleen: 292.5 thyroid gland: 154.8 -FAM78A C9orf59, FLJ00024 ENSG00000126882 Family with sequence similarity 78, member A 9 131258076-131276547 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021472, HPA023914 Uncertain Uncertain Nucleus
Vesicles Mixed lymph node: 27.8 -NUP214 CAIN, CAN, D9S46E, N214 ENSG00000126883 Nucleoporin 214kDa 9 131125561-131234670 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048789 Supported Nucleus
Vesicles
Focal adhesion sites Expressed in all testis: 122.9 -CTAG2 CAMEL, CT6.2a, CT6.2b, ESO2, LAGE-1, LAGE-1a, LAGE-1b, LAGE1, MGC138724, MGC3803 ENSG00000126890 Cancer/testis antigen 2 X 154651972-154653579 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071467 Supported Group enriched 7 fallopian tube: 2.5;heart muscle: 2.5;placenta: 3.6;skeletal muscle: 1.2;testis: 6.0 pancreas: 0.4 -AVPR2 DIR, DIR3, V2R ENSG00000126895 Arginine vasopressin receptor 2 X 153902531-153907166 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA046678 Approved Tissue enhanced 0 adipose tissue: 5.8 heart muscle: 2.8 -SLC10A3 DXS253E, P3 ENSG00000126903 Solute carrier family 10, member 3 X 154487306-154490690 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA021656 Approved Approved Intermediate filaments Expressed in all gallbladder: 33.2 -MAP2K2 MEK2, PRKMK2 ENSG00000126934 Mitogen-activated protein kinase kinase 2 19 4090321-4124129 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003835, HPA051993 Supported Validated Cytosol Expressed in all duodenum: 138.7 -HNRNPH2 FTP3, hnRNPH', HNRPH', HNRPH2 ENSG00000126945 Heterogeneous nuclear ribonucleoprotein H2 (H') X 101408295-101414133 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000914, HPA001359, CAB004436, HPA016884 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 212.9 -ARMCX1 ALEX1, GASP7 ENSG00000126947 Armadillo repeat containing, X-linked 1 X 101550531-101554700 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005685, CAB020695 Supported Approved Nucleus
Mitochondria
Cytosol Expressed in all ovary: 58.9 -TMEM35 FLJ14084 ENSG00000126950 Transmembrane protein 35 X 101078720-101096364 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048583 Supported Tissue enhanced 0 cerebral cortex: 42.5;seminal vesicle: 64.8 prostate: 34.0 -NXF5 ENSG00000126952 Nuclear RNA export factor 5 X 101832112-101857577 Disease related genes, Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA002079 Uncertain Not detected spleen: 0.1 -TIMM8A DDP, DFN1, MTS ENSG00000126953 Translocase of inner mitochondrial membrane 8 homolog A (yeast) X 101345661-101349196 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003628 Supported Validated Mitochondria Mixed parathyroid gland: 10.5 -ZC4H2 HCA127, KIAA1166, WWS ENSG00000126970 Zinc finger, C4H2 domain containing X 64915802-65034713 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049584 Approved Approved Vesicles
Microtubules Mixed parathyroid gland: 17.2 -CANX CNX, IP90, P90 ENSG00000127022 Calnexin 5 179678628-179730925 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004738, HPA009433, HPA009696 Supported Validated Endoplasmic reticulum Expressed in all thyroid gland: 871.4 -CPSF3L CPSF73L, FLJ20542, INT11, INTS11, RC-68 ENSG00000127054 Cleavage and polyadenylation specific factor 3-like 1 1311585-1324691 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028379, HPA029025 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 76.5 -RGS13 ENSG00000127074 Regulator of G-protein signaling 13 1 192636138-192660306 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044952 Uncertain Group enriched 6 appendix: 14.8;lymph node: 69.2;tonsil: 38.3 small intestine: 7.3 -IPPK C9orf12, FLJ13163, INSP5K2, IP5K, IPK1 ENSG00000127080 Inositol 1,3,4,5,6-pentakisphosphate 2-kinase 9 92613184-92670265 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020603 Uncertain Approved Cytosol Mixed skin: 34.2 -ZNF484 BA526D8.4, FLJ33884 ENSG00000127081 Zinc finger protein 484 9 92845031-92878038 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028973 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Mixed parathyroid gland: 6.8 -OMD osteoadherin, SLRR2C ENSG00000127083 Osteomodulin 9 92414245-92424461 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005731 Approved Mixed cervix: 36.2 -FGD3 FLJ00004, ZFYVE5 ENSG00000127084 FYVE, RhoGEF and PH domain containing 3 9 92947451-93036236 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020963, HPA021018 Approved Approved Nucleus
Cytosol Tissue enhanced 0 lymph node: 31.8 spleen: 29.5 -HIVEP3 FLJ16752, KBP-1, KBP1, KIAA1555, KRC, Schnurri-3, SHN3, ZAS3, ZNF40C ENSG00000127124 Human immunodeficiency virus type I enhancer binding protein 3 1 41506365-42035925 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA005728 Approved Approved Nucleoplasm Mixed skin: 5.7 -PPCS FLJ11838 ENSG00000127125 Phosphopantothenoylcysteine synthetase 1 42456117-42473385 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031361, HPA031363 Approved Approved Nucleus
Nucleoli fibrillar center
Mitochondria Expressed in all thyroid gland: 110.1 -EDN2 ET2 ENSG00000127129 Endothelin 2 1 41478775-41484673 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028459 Uncertain Approved Cytosol Tissue enhanced 0 esophagus: 10.7;small intestine: 18.4 epididymis: 5.4 -BCL11B CTIP-2, CTIP2, hRIT1-alpha, ZNF856B ENSG00000127152 B-cell CLL/lymphoma 11B (zinc finger protein) 14 99169287-99271524 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049117 Supported Supported Approved Nucleus
Nucleoli fibrillar center Tissue enhanced 0 lymph node: 12.4;skin: 18.8 tonsil: 7.7 -COX7C ENSG00000127184 Cytochrome c oxidase subunit VIIc 5 86617904-86620962 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046647 Approved Expressed in all skeletal muscle: 822.1 -TRAF2 TRAP3 ENSG00000127191 TNF receptor-associated factor 2 9 136881912-136926607 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004603, HPA009972, HPA010634 Uncertain Validated Cytosol Expressed in all lymph node: 23.1 -ABHD8 FLJ11743, MGC14280, MGC2512 ENSG00000127220 Abhydrolase domain containing 8 19 17292131-17310236 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037658, HPA058209 Approved Approved Nucleoplasm
Nuclear bodies Mixed cerebral cortex: 28.6 -MASP1 CRARF, MASP, PRSS5 ENSG00000127241 Mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 3 187217285-187292022 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001617, HPA009641 Supported Supported Nucleoplasm
Cytosol Tissue enhanced 0 cervix, uterine: 155.2 endometrium: 97.4 -ATP13A4 DKFZp761I1011, FLJ37958 ENSG00000127249 ATPase type 13A4 3 193402077-193593111 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051932 Approved Nucleoplasm Tissue enhanced 0 epididymis: 89.1;parathyroid gland: 129.5;thyroid gland: 68.2 lung: 56.5 -HRASLS H-REV107, HRASLS1 ENSG00000127252 HRAS-like suppressor 3 193241125-193277738 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA051179 Uncertain Approved Focal adhesion sites
Cytosol Group enriched 6 skeletal muscle: 27.2;testis: 95.4 thyroid gland: 10.0 -HELB ENSG00000127311 Helicase (DNA) B 12 66302545-66347645 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed lymph node: 3.5 -RAP1B DKFZp586H0723, K-REV, RAL1B ENSG00000127314 RAP1B, member of RAS oncogene family 12 68610839-68671901 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all lymph node: 247.4 -IL22 IL-21, IL-22, IL-D110, IL-TIF, ILTIF, MGC79382, MGC79384, TIFa, TIFIL-23, zcyto18 ENSG00000127318 Interleukin 22 12 68248242-68253607 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Not detected urinary bladder: 0.9 -TSPAN8 CO-029, TM4SF3 ENSG00000127324 Tetraspanin 8 12 71125085-71441898 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026009, HPA044337 Supported Approved Nucleoplasm Tissue enhanced 0 colon: 926.1;duodenum: 931.2;rectum: 922.7;small intestine: 928.3 stomach: 574.1 -BEST3 MGC13168, MGC40411, VMD2L3 ENSG00000127325 Bestrophin 3 12 69643360-69699476 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA054582 Approved Tissue enhanced 0 cerebral cortex: 16.4;skeletal muscle: 12.2 testis: 5.9 -RAB3IP FLJ22548, RABIN3, RABIN8 ENSG00000127328 RAB3A interacting protein 12 69738681-69823204 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039794 Uncertain Approved Intermediate filaments Tissue enhanced 0 testis: 132.9 epididymis: 51.7 -PTPRB PTPB ENSG00000127329 Protein tyrosine phosphatase, receptor type, B 12 70515866-70637440 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004782, HPA067868 Uncertain Approved Vesicles
Plasma membrane
Cell Junctions Mixed lung: 54.1 -DYRK2 ENSG00000127334 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 12 67648338-67665406 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027230, HPA056902 Approved Supported Nucleoplasm
Cytosol Expressed in all small intestine: 31.7 -YEATS4 GAS41, NuBI-1, YAF9 ENSG00000127337 YEATS domain containing 4 12 69359703-69390796 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072532 Approved Nucleoplasm
Nuclear membrane Expressed in all testis: 68.8 -TAS2R3 T2R3 ENSG00000127362 Taste receptor, type 2, member 3 7 141764097-141765197 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected ovary: 0.5 -TAS2R4 T2R4 ENSG00000127364 Taste receptor, type 2, member 4 7 141778442-141780819 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed skin: 1.7 -TAS2R5 T2R5 ENSG00000127366 Taste receptor, type 2, member 5 7 141790217-141791367 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 5.0 epididymis: 3.3 -CRYGN ENSG00000127377 Crystallin, gamma N 7 151428835-151440813 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA050788 Uncertain Tissue enhanced 0 seminal vesicle: 3.3;thyroid gland: 12.8 parathyroid gland: 1.9 -LRRC61 FLJ31392, HSPC295, MGC3036 ENSG00000127399 Leucine rich repeat containing 61 7 150322639-150338150 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA019355 Approved Approved Nucleoplasm Mixed fallopian tube: 22.4 -TRPV5 CaT2, ECAC1 ENSG00000127412 Transient receptor potential cation channel, subfamily V, member 5 7 142908101-142933808 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level No evidence Evidence at protein level HPA063175 Approved Not detected kidney: 0.5 -IDUA MPS1 ENSG00000127415 Iduronidase, alpha-L- 4 986997-1004506 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025901, HPA046979, HPA054254 Supported Expressed in all spleen: 16.9 -FGFRL1 ENSG00000127418 Fibroblast growth factor receptor-like 1 4 1009936-1026897 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB026019, HPA068828 Approved Approved Nucleoplasm
Vesicles
Cytosol Expressed in all thyroid gland: 67.5 -TMEM175 MGC4618 ENSG00000127419 Transmembrane protein 175 4 932387-958656 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057160 Approved Approved Nucleus
Nuclear membrane Expressed in all cerebral cortex: 20.8 -AUNIP AIBp, C1orf135, MGC2603 ENSG00000127423 Aurora kinase A and ninein interacting protein 1 25831913-25859458 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028730 Uncertain Supported Centrosome Tissue enriched 7 testis: 29.1 bone marrow: 3.8 -PIN1 dod ENSG00000127445 Peptidylprolyl cis/trans isomerase, NIMA-interacting 1 19 9835257-9849682 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004528, CAB009326, HPA068650 Approved Validated Nucleoplasm
Cytosol Expressed in all cerebral cortex: 137.3 -FBXL12 Fbl12, FLJ20188 ENSG00000127452 F-box and leucine-rich repeat protein 12 19 9810267-9827816 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002843 Approved Mitochondria Expressed in all placenta: 21.7 -EMC1 KIAA0090 ENSG00000127463 ER membrane protein complex subunit 1 1 19215664-19251552 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048904 Approved Approved Microtubules
Cytokinetic bridge Expressed in all placenta: 34.3 -PLA2G5 ENSG00000127472 Phospholipase A2, group V 1 20028179-20091190 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053361 Approved Tissue enhanced 0 heart muscle: 50.0 seminal vesicle: 19.5 -UBR4 KIAA0462, KIAA1307, RBAF600, ZUBR1 ENSG00000127481 Ubiquitin protein ligase E3 component n-recognin 4 1 19074506-19210276 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013394, HPA021046 Approved Supported Nucleoplasm
Centrosome
Cytosol Expressed in all skin: 90.6 -HP1BP3 HP1-BP74 ENSG00000127483 Heterochromatin protein 1, binding protein 3 1 20742661-20787323 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028215, HPA054295 Supported Supported Nuclear speckles Expressed in all endometrium: 191.2 -ADGRE2 CD312, EMR2 ENSG00000127507 Adhesion G protein-coupled receptor E2 19 14732393-14778541 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055200 Uncertain Vesicles Tissue enhanced 0 appendix: 27.6;spleen: 15.7 adipose tissue: 5.9 -SIN3B KIAA0700 ENSG00000127511 SIN3 transcription regulator family member B 19 16829400-16880353 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050329 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all parathyroid gland: 110.4 -OR7A10 ENSG00000127515 Olfactory receptor, family 7, subfamily A, member 10 19 14840948-14841877 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -SLC35E1 FLJ14251 ENSG00000127526 Solute carrier family 35, member E1 19 16549831-16572382 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016570, HPA062214 Approved Validated Golgi apparatus Expressed in all parathyroid gland: 29.2 -EPS15L1 eps15R ENSG00000127527 Epidermal growth factor receptor pathway substrate 15-like 1 19 16355239-16472085 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019237, HPA055309 Uncertain Approved Vesicles Expressed in all parathyroid gland: 25.7 -KLF2 LKLF ENSG00000127528 Kruppel-like factor 2 19 16324817-16327874 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA055964 Approved Approved Nucleoplasm Expressed in all adipose tissue: 115.7 -OR7C2 OR19-18, OR7C3 ENSG00000127529 Olfactory receptor, family 7, subfamily C, member 2 19 14941489-14942448 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA047295 Uncertain Not detected epididymis: 0.0 -OR7C1 OR19-5, OR7C4 ENSG00000127530 Olfactory receptor, family 7, subfamily C, member 1 19 14799146-14800211 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047127 Uncertain Tissue enhanced 0 epididymis: 3.4;parathyroid gland: 4.9;testis: 3.9 seminal vesicle: 1.5 -F2RL3 PAR4 ENSG00000127533 Coagulation factor II (thrombin) receptor-like 3 19 16888860-16892606 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed thyroid gland: 7.8 -UQCR11 QCR10, UQCR ENSG00000127540 Ubiquinol-cytochrome c reductase, complex III subunit XI 19 1597172-1605490 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Expressed in all skeletal muscle: 111.9 -GFER ALR, ERV1, HERV1, HPO1, HPO2, HSS ENSG00000127554 Growth factor, augmenter of liver regeneration 16 1984207-1987749 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041227, HPA063553 Approved Validated Mitochondria
Cytosol Expressed in all small intestine: 51.0 -SYNGR3 ENSG00000127561 Synaptogyrin 3 16 1989660-1994275 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034278, HPA042842 Supported Approved Plasma membrane Tissue enriched 7 cerebral cortex: 82.8 adrenal gland: 12.5 -PKMYT1 MYT1, PPP1R126 ENSG00000127564 Protein kinase, membrane associated tyrosine/threonine 1 16 2968024-2980539 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068860 Supported Nucleus
Nucleoli
Golgi apparatus Tissue enhanced 0 bone marrow: 17.0;testis: 28.3 lymph node: 9.8 -WFIKKN1 C16orf12, RJD2, WFDC20A, WFIKKN ENSG00000127578 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 16 629239-634116 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB025858, HPA043362, HPA044237 Uncertain Not detected spleen: 0.1 -WDR24 C16orf21, DKFZp434F054, JFP7 ENSG00000127580 WD repeat domain 24 16 684622-690444 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039506 Approved Expressed in all testis: 11.9 -FBXL16 C16orf22, Fbl16, MGC33974 ENSG00000127585 F-box and leucine-rich repeat protein 16 16 692498-705829 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039504, HPA056354 Supported Tissue enriched 23 cerebral cortex: 187.0 testis: 8.0 -CHTF18 C16orf41, C321D2.4, CHL12, Ctf18 ENSG00000127586 Chromosome transmission fidelity factor 18 16 788046-800737 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040976, HPA056209 Validated Nucleoplasm
Cytosol Mixed testis: 4.7 -GNG13 G(gamma)13, h2-35 ENSG00000127588 Guanine nucleotide binding protein (G protein), gamma 13 16 798041-800733 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA046272 Approved Tissue enhanced 0 cerebral cortex: 2.5;duodenum: 1.4;small intestine: 1.5 testis: 0.7 -MACF1 ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF ENSG00000127603 Microtubule-actin crosslinking factor 1 1 39081316-39487177 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013713, HPA068064, HPA068103 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Expressed in all lung: 137.3 -SMARCA4 BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2 ENSG00000127616 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 19 10961001-11065395 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004208 Supported Supported Nucleoplasm Expressed in all testis: 39.5 -KDM4B JMJD2B, KIAA0876, TDRD14B ENSG00000127663 Lysine (K)-specific demethylase 4B 19 4969113-5153595 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062872 Supported Nucleus
Cytosol Expressed in all thyroid gland: 19.8 -TICAM1 MGC35334, PRVTIRB, TICAM-1, TRIF ENSG00000127666 Toll-like receptor adaptor molecule 1 19 4815932-4831704 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042460 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Expressed in all esophagus: 22.1 -METTL25 C12orf26, FLJ22789 ENSG00000127720 Methyltransferase like 25 12 82358497-82479236 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039534, HPA041207 Uncertain Uncertain Plasma membrane
Mitochondria
Cytosol Mixed testis: 13.3 -IL17B IL-17B, IL-20, MGC138900, MGC138901, NIRF, ZCYTO7 ENSG00000127743 Interleukin 17B 5 149371324-149404202 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042441 Uncertain Tissue enhanced 0 breast: 4.1 smooth muscle: 3.5 -EMC6 MGC2963, TMEM93 ENSG00000127774 ER membrane protein complex subunit 6 17 3668815-3669668 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062681 Uncertain Approved Nucleus
Centrosome Expressed in all skeletal muscle: 49.2 -OR1E2 OR17-135, OR17-93, OR1E4 ENSG00000127780 Olfactory receptor, family 1, subfamily E, member 2 17 3432870-3433841 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -METTL16 METT10D, MGC3329 ENSG00000127804 Methyltransferase like 16 17 2405562-2511891 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020352, HPA059798 Uncertain Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 17.1 -TUBA4A FLJ30169, H2-ALPHA, TUBA1 ENSG00000127824 Tubulin, alpha 4a 2 219249711-219278170 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004621, CAB005887, HPA039247, HPA043684, HPA063394 Approved Validated Microtubules Expressed in all skin: 181.9 -VIL1 D2S1471, VIL ENSG00000127831 Villin 1 2 218419092-218453295 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002452, HPA006884, HPA006885 Supported Supported Plasma membrane Group enriched 7 colon: 175.1;duodenum: 409.9;rectum: 199.9;small intestine: 489.9 gallbladder: 44.9 -AAMP ENSG00000127837 Angio-associated, migratory cell protein 2 218264123-218270257 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017717, HPA031868 Approved Supported Microtubules
Cytosol Expressed in all thyroid gland: 114.8 -PNKD BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, PDC, PKND1, TAHCCP2 ENSG00000127838 Paroxysmal nonkinesigenic dyskinesia 2 218270392-218346793 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010134, HPA017068 Approved Validated Mitochondria Expressed in all prostate: 117.3 -TNFRSF19 TAJ, TAJ-alpha, TRADE, TROY ENSG00000127863 Tumor necrosis factor receptor superfamily, member 19 13 23570370-23676104 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010135 Approved Nucleoplasm
Mitochondria Tissue enhanced 0 skin: 129.2 fallopian tube: 49.9 -RNF6 DKFZp686P0776 ENSG00000127870 Ring finger protein (C3H2C3 type) 6 13 26132115-26222493 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039343, HPA040048 Approved Supported Nuclear membrane Expressed in all testis: 60.8 -ECHS1 SCEH ENSG00000127884 Enoyl CoA hydratase, short chain, 1, mitochondrial 10 133362480-133373689 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003783, HPA021995, HPA022476 Supported Validated Mitochondria Expressed in all liver: 437.5 -ZNF835 BC37295_3 ENSG00000127903 Zinc finger protein 835 19 56661981-56671783 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051136, HPA055356 Uncertain Approved Actin filaments Mixed ovary: 5.3 -AKAP9 AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO ENSG00000127914 A kinase (PRKA) anchor protein 9 7 91940867-92110673 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008548, CAB012909, HPA026109 Supported Validated Golgi apparatus
Vesicles
Centrosome Expressed in all parathyroid gland: 37.2 -GNG11 GNGT11 ENSG00000127920 Guanine nucleotide binding protein (G protein), gamma 11 7 93921699-93928610 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045255 Uncertain Expressed in all placenta: 122.3 -SHFM1 DSS1, ECD, SEM1, SHFD1, Shfdg1, SHSF1 ENSG00000127922 Split hand/foot malformation (ectrodactyly) type 1 7 96481626-96709891 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA020429, HPA072648 Uncertain Approved Cytosol Expressed in all testis: 222.1 -GNGT1 GNG1 ENSG00000127928 Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 7 93591573-93911265 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042721 Supported Tissue enriched 6 placenta: 3.9 urinary bladder: 0.6 -HIP1 ILWEQ ENSG00000127946 Huntingtin interacting protein 1 7 75533300-75738962 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013606, CAB015334, CAB016402, HPA017964 Supported Validated Vesicles Mixed testis: 35.1 -PTPN12 PTP-PEST, PTPG1 ENSG00000127947 Protein tyrosine phosphatase, non-receptor type 12 7 77537275-77640071 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007097 Approved Approved Plasma membrane
Cytosol Expressed in all placenta: 106.3 -POR CYPOR, FLJ26468 ENSG00000127948 P450 (cytochrome) oxidoreductase 7 75899200-75986855 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004372, HPA010136 Supported Approved Nucleoplasm
Vesicles
Cytosol Expressed in all thyroid gland: 219.8 -FGL2 pT49, T49 ENSG00000127951 Fibrinogen-like 2 7 77193371-77199826 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021011, HPA026682 Supported Expressed in all spleen: 228.4 -STYXL1 DUSP24, MK-STYX ENSG00000127952 Serine/threonine/tyrosine interacting-like 1 7 75996338-76048004 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA050261 Uncertain Approved Nuclear speckles Expressed in all fallopian tube: 45.5 -STEAP4 FLJ23153, STAMP2, TIARP, TNFAIP9 ENSG00000127954 STEAP family member 4 7 88270892-88306891 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA075871 Supported Golgi apparatus Expressed in all adipose tissue: 129.9 -GNAI1 ENSG00000127955 Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 7 80133955-80219402 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022449, HPA042141 Approved Supported Nucleus
Nucleoli
Centrosome Expressed in all cerebral cortex: 94.8 -PEX1 ZWS, ZWS1 ENSG00000127980 Peroxisomal biogenesis factor 1 7 92487020-92528531 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020235 Approved Supported Peroxisomes Expressed in all parathyroid gland: 22.2 -MTERF1 MTERF ENSG00000127989 Mitochondrial transcription termination factor 1 7 91692008-91880720 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044894, HPA069560 Uncertain Supported Mitochondria Expressed in all lymph node: 16.6 -SGCE DYT11 ENSG00000127990 Sarcoglycan, epsilon 7 94585230-94656209 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA074790 Approved Nucleoplasm
Golgi apparatus
Vesicles
Plasma membrane Mixed ovary: 132.8 -RBM48 C7orf64, DKFZp564O0523, HSPC304 ENSG00000127993 RNA binding motif protein 48 7 92528773-92538005 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA021777, HPA025306 Uncertain Validated Nucleoplasm Expressed in all cerebral cortex: 21.8 -CASD1 C7orf12, FLJ21213, FLJ21879 ENSG00000127995 CAS1 domain containing 1 7 94509219-94557019 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044404 Uncertain Approved Nucleoplasm Expressed in all cerebral cortex: 38.9 -ZNF780B ZNF779 ENSG00000128000 Zinc finger protein 780B 19 40028260-40056209 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA003311 Uncertain Approved Nucleus
Centrosome Mixed thyroid gland: 8.0 -LRFN1 KIAA1484, SALM2 ENSG00000128011 Leucine rich repeat and fibronectin type III domain containing 1 19 39306568-39315336 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 5.5 spleen: 2.2 -ZFP36 G0S24, NUP475, RNF162A, TIS11, TTP ENSG00000128016 ZFP36 ring finger protein 19 39406813-39409412 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA006009 Approved Approved Vesicles Expressed in all gallbladder: 931.9 -SRD5A3 FLJ13352, SRD5A2L, SRD5A2L1 ENSG00000128039 Steroid 5 alpha-reductase 3 4 55346109-55373096 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027006 Uncertain Approved Plasma membrane
Cytosol Expressed in all gallbladder: 28.3 -SPINK2 HUSI-II ENSG00000128040 Serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 4 56809860-56821742 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020824, HPA026813 Supported Tissue enriched 15 epididymis: 6311.3 testis: 427.3 -RASL11B ENSG00000128045 RAS-like, family 11, member B 4 52862290-52866835 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057803 Approved Approved Nuclear bodies Tissue enhanced 0 ovary: 25.8;parathyroid gland: 29.9 cerebral cortex: 13.6 -PAICS ADE2H1, AIRC, PAIS ENSG00000128050 Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 4 56435741-56464579 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035895, HPA041538 Uncertain Approved Cytosol Expressed in all parathyroid gland: 72.8 -KDR CD309, FLK1, VEGFR, VEGFR2 ENSG00000128052 Kinase insert domain receptor 4 55078477-55125589 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004028 Approved Supported Plasma membrane Tissue enhanced 0 placenta: 118.2 thyroid gland: 54.5 -PPAT GPAT, PRAT ENSG00000128059 Phosphoribosyl pyrophosphate amidotransferase 4 56393362-56435615 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036091, HPA036092 Approved Approved Midbody ring Mixed testis: 16.2 -TUBGCP6 DJ402G11.6, GCP6, KIAA1669 ENSG00000128159 Tubulin, gamma complex associated protein 6 22 50217689-50244992 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043928 Approved Expressed in all parathyroid gland: 27.6 -ADM2 AM2, FLJ21135 ENSG00000128165 Adrenomedullin 2 22 50481556-50486440 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 thyroid gland: 19.2 kidney: 5.9 -DGCR6L FLJ10666 ENSG00000128185 DiGeorge syndrome critical region gene 6-like 22 20314276-20320080 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 97.0 -DGCR8 C22orf12, DGCRK6, Gy1, pasha ENSG00000128191 DGCR8 microprocessor complex subunit 22 20080232-20111877 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 22.1 -ASPHD2 FLJ39838 ENSG00000128203 Aspartate beta-hydroxylase domain containing 2 22 26429273-26445015 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000820 Uncertain Tissue enhanced 0 cerebral cortex: 12.9 stomach: 7.9 -VPREB3 8HS20 ENSG00000128218 Pre-B lymphocyte 3 22 23752743-23754468 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA003041 Supported Tissue enhanced 0 lymph node: 119.1;tonsil: 99.5 spleen: 62.3 -SDF2L1 AP000553.C22.4, OTTHUMT00000075032 ENSG00000128228 Stromal cell-derived factor 2-like 1 22 21642261-21644298 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005638 Approved Expressed in all thyroid gland: 45.2 -GAL3ST1 CST ENSG00000128242 Galactose-3-O-sulfotransferase 1 22 30554635-30574587 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001220 Approved Approved Vesicles Tissue enhanced 0 duodenum: 23.9;small intestine: 27.7 cerebral cortex: 18.2 -YWHAH YWHA1 ENSG00000128245 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 22 31944461-31957603 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025918 Uncertain Tissue enriched 7 cerebral cortex: 899.0 lung: 138.0 -RFPL1 RNF78 ENSG00000128250 Ret finger protein-like 1 22 29438583-29442455 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048320, HPA072380 Approved Nuclear speckles
Plasma membrane Tissue enriched 6 cerebral cortex: 27.3 ovary: 4.4 -RFPL2 RNF79 ENSG00000128253 Ret finger protein-like 2 22 32190435-32203477 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048320, HPA072380 Approved Nuclear speckles
Plasma membrane Tissue enriched 9 prostate: 7.0 cerebral cortex: 0.8 -GNAZ ENSG00000128266 Guanine nucleotide binding protein (G protein), alpha z polypeptide 22 23070361-23125037 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003011 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 49.8 seminal vesicle: 22.7 -MGAT3 GNT-III ENSG00000128268 Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 22 39457344-39492194 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA017598 Approved Tissue enhanced 0 cerebral cortex: 38.7 small intestine: 33.2 -ADORA2A ADORA2, RDC8 ENSG00000128271 Adenosine A2a receptor 22 24417879-24442360 Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 bone marrow: 9.6 lymph node: 7.7 -ATF4 CREB-2, TAXREB67, TXREB ENSG00000128272 Activating transcription factor 4 22 39519695-39522685 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011596 Approved Supported Microtubule organizing center
Cytosol Expressed in all bone marrow: 531.3 -A4GALT A14GALT, Gb3S, P(k) ENSG00000128274 Alpha 1,4-galactosyltransferase 22 42692121-42721298 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA001141, HPA076542 Supported Mitochondria Mixed seminal vesicle: 30.1 -RFPL3 ENSG00000128276 Ret finger protein-like 3 22 32354885-32361161 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048320, HPA072380 Approved Nuclear speckles
Plasma membrane Tissue enriched 7 testis: 4.0 epididymis: 0.5 -CDC42EP1 Borg5, CEP1, MSE55 ENSG00000128283 CDC42 effector protein (Rho GTPase binding) 1 22 37560447-37569405 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006379 Approved Supported Plasma membrane
Actin filaments Expressed in all stomach: 107.7 -APOL3 APOLIII, CG12-1 ENSG00000128284 Apolipoprotein L, 3 22 36140330-36166177 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036228 Approved Nuclear bodies
Mitochondria Mixed spleen: 65.0 -MCHR1 GPR24, MCH1R, SLC1 ENSG00000128285 Melanin-concentrating hormone receptor 1 22 40678750-40682814 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 8.6 ovary: 2.1 -TPST2 TANGO13B ENSG00000128294 Tyrosylprotein sulfotransferase 2 22 26521983-26596717 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021054 Approved Expressed in all epididymis: 133.6 -BAIAP2L2 FLJ22582 ENSG00000128298 BAI1-associated protein 2-like 2 22 38084889-38110670 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003043 Approved Tissue enhanced 0 duodenum: 110.2;small intestine: 99.5 gallbladder: 27.6 -MPST MST, TST2, TUM1 ENSG00000128309 Mercaptopyruvate sulfurtransferase 22 37019635-37029822 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001240 Approved Approved Mitochondria
Cytosol Mixed duodenum: 111.8 -GALR3 ENSG00000128310 Galanin receptor 3 22 37823382-37825495 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected cerebral cortex: 0.2 -TST RDS ENSG00000128311 Thiosulfate sulfurtransferase (rhodanese) 22 37010859-37020183 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003044, HPA003643, CAB009546 Supported Supported Mitochondria Expressed in all colon: 146.0 -APOL5 APOLV ENSG00000128313 Apolipoprotein L, 5 22 35717872-35729483 Plasma proteins, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040968 Uncertain Not detected skeletal muscle: 0.5 -IGLL1 14.1, CD179B, IGL5, IGLL, IGVPB ENSG00000128322 Immunoglobulin lambda-like polypeptide 1 22 23573125-23580308 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051134, HPA071406 Approved Approved Endoplasmic reticulum Group enriched 17 bone marrow: 44.3;testis: 16.1 tonsil: 1.7 -APOL2 APOL-II ENSG00000128335 Apolipoprotein L, 2 22 36226203-36239954 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001078 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all gallbladder: 65.0 -RAC2 EN-7 ENSG00000128340 Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 22 37225261-37244448 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022946, HPA047820 Approved Expressed in all lymph node: 449.5 -LIF CDF, DIA, HILDA ENSG00000128342 Leukemia inhibitory factor 22 30240447-30246851 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA018844, CAB025985 Approved Validated Cytosol Tissue enhanced 0 gallbladder: 75.8 urinary bladder: 43.5 -C22orf23 EVG1, FLJ32787, LOC84645 ENSG00000128346 Chromosome 22 open reading frame 23 22 37943050-37953669 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 145.8 seminal vesicle: 50.5 -APOBEC3A ARP3, PHRBN ENSG00000128383 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 22 38952741-38992778 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043237, HPA056980, HPA066719 Approved Uncertain Nucleoplasm Tissue enhanced 0 appendix: 30.4;bone marrow: 59.1 spleen: 19.8 -APOBEC3F ARP8, BK150C2.4.MRNA, KA6 ENSG00000128394 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 22 39040604-39053910 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA073637 Uncertain Nucleoplasm
Cytosol Mixed lymph node: 18.8 -RIBC2 C22orf11, DKFZp566F0546, FLJ25720 ENSG00000128408 RIB43A domain with coiled-coils 2 22 45413691-45432496 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA003210 Uncertain Group enriched 9 fallopian tube: 15.8;testis: 37.3 parathyroid gland: 3.1 -KRT17 PCHC1 ENSG00000128422 Keratin 17, type I 17 41619437-41624842 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000029, HPA000452, HPA000453, HPA000539, HPA045062 Supported Supported Intermediate filaments Tissue enhanced 0 breast: 219.7;seminal vesicle: 223.4;urinary bladder: 334.2 prostate: 106.2 -EMC4 FLJ90746, MGC24415, PIG17, TMEM85 ENSG00000128463 ER membrane protein complex subunit 4 15 34224999-34230156 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026868, HPA053440 Approved Approved Cell Junctions
Focal adhesion sites Expressed in all epididymis: 120.7 -RNF112 BFP, ZNF179 ENSG00000128482 Ring finger protein 112 17 19411125-19417276 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015970 Approved Approved Nuclear speckles Tissue enhanced 0 cerebral cortex: 33.0 prostate: 9.6 -SPECC1 CYTSB, FLJ36955, HCMOGT-1, NSP ENSG00000128487 Sperm antigen with calponin homology and coiled-coil domains 1 17 20009344-20319026 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021421, HPA021430 Approved Expressed in all testis: 67.2 -CPA4 CPA3 ENSG00000128510 Carboxypeptidase A4 7 130293134-130324180 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021030 Uncertain Approved Nucleoplasm
Centrosome
Cytosol Tissue enriched 7 skin: 68.0 esophagus: 10.0 -DOCK4 FLJ34238, KIAA0716 ENSG00000128512 Dedicator of cytokinesis 4 7 111726110-112206411 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071516 Supported Nucleoli
Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 31.8 lung: 27.6 -POT1 DKFZp586D211, hPot1 ENSG00000128513 Protection of telomeres 1 7 124822386-124929983 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068538 Supported Nucleus Mixed thyroid gland: 21.5 -TAS2R16 T2R16 ENSG00000128519 Taste receptor, type 2, member 16 7 122994704-122995700 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.0 -ATP6V1F ATP6S14, VATF, Vma7 ENSG00000128524 ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 7 128862826-128865844 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009529, HPA048700, HPA062011 Supported Expressed in all cerebral cortex: 288.9 -LSM8 YJR022W ENSG00000128534 LSM8 homolog, U6 small nuclear RNA associated 7 118184032-118192824 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020116 Uncertain Approved Nucleoplasm
Vesicles Expressed in all lymph node: 53.1 -CDHR3 CDH28, FLJ23834, FLJ44366 ENSG00000128536 Cadherin-related family member 3 7 105876796-106033773 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011218 Uncertain Approved Nucleoli fibrillar center Tissue enriched 8 fallopian tube: 145.5 lung: 19.2 -PRKRIP1 C114, FLJ13902, KRBOX3 ENSG00000128563 PRKR interacting protein 1 (IL11 inducible) 7 102363872-102426676 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051146 Uncertain Supported Actin filaments
Cytosol Expressed in all testis: 34.7 -VGF SCG7, SgVII ENSG00000128564 VGF nerve growth factor inducible 7 101162509-101165593 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055177, HPA072505 Supported Supported Vesicles Tissue enriched 22 cerebral cortex: 46.2 adipose tissue: 2.0 -PODXL Gp200, PC, PCLP ENSG00000128567 Podocalyxin-like 7 131500262-131558217 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220 Supported Approved Vesicles
Plasma membrane
Microtubule organizing center Mixed fallopian tube: 29.2 -FOXP2 CAGH44, SPCH1, TNRC10 ENSG00000128573 Forkhead box P2 7 114086327-114693772 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000382, HPA000383, HPA001679 Supported Supported Nucleoplasm
Vesicles
Centrosome Mixed endometrium: 13.6 -STRIP2 FAM40B, FAR11B, KIAA1170 ENSG00000128578 Striatin interacting protein 2 7 129434433-129488399 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019657 Uncertain Supported Cytosol Tissue enhanced 0 cerebral cortex: 14.0;testis: 23.5 skeletal muscle: 9.7 -IFT22 DKFZp761N0823, FLJ13225, FLJ14117, RABL5 ENSG00000128581 Intraflagellar transport 22 7 101313367-101321823 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042930 Approved Approved Microtubules
Cytosol Expressed in all testis: 138.8 -MKLN1 TWA2 ENSG00000128585 Muskelin 1, intracellular mediator containing kelch motifs 7 131110096-131496636 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022817, HPA041810 Approved Approved Vesicles
Plasma membrane
Cytosol Expressed in all prostate: 25.2 -DNAJB9 MDG1 ENSG00000128590 DnaJ (Hsp40) homolog, subfamily B, member 9 7 108569568-108574850 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040967, HPA041553 Supported Approved Endoplasmic reticulum
Cytosol Expressed in all thyroid gland: 113.1 -FLNC ABP-280, ABPL, FLN2 ENSG00000128591 Filamin C, gamma 7 128830377-128859274 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006135 Supported Supported Plasma membrane
Cytosol Tissue enhanced 0 skeletal muscle: 384.8 smooth muscle: 158.7 -LRRC4 NAG14 ENSG00000128594 Leucine rich repeat containing 4 7 128027071-128032107 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051100 Uncertain Golgi apparatus Tissue enhanced 0 cerebral cortex: 53.0 parathyroid gland: 13.0 -CALU ENSG00000128595 Calumenin 7 128739292-128771807 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006018 Supported Supported Endoplasmic reticulum Expressed in all smooth muscle: 439.7 -CCDC136 DKFZP434G156, KIAA1793, NAG6 ENSG00000128596 Coiled-coil domain containing 136 7 128790757-128822132 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010647, HPA071015 Supported Approved Nucleoli Tissue enriched 7 testis: 307.5 cerebral cortex: 44.3 -SMO FZD11, SMOH ENSG00000128602 Smoothened, frizzled class receptor 7 129188872-129213545 Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB011446 Approved Mixed ovary: 30.3 -IRF5 ENSG00000128604 Interferon regulatory factor 5 7 128937612-128950035 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046700 Approved Mixed spleen: 25.3 -LRRC17 H_RG318M05.3, P37NB ENSG00000128606 Leucine rich repeat containing 17 7 102912991-102944949 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030139 Uncertain Approved Nucleoplasm
Nuclear speckles
Plasma membrane Tissue enhanced 0 ovary: 98.8 gallbladder: 46.9 -KLHDC10 KIAA0265, slim ENSG00000128607 Kelch domain containing 10 7 130070510-130135720 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020119 Approved Approved Nucleoplasm Expressed in all testis: 69.2 -NDUFA5 B13, CI-13kB, CI-13KD-B, NUFM, UQOR13 ENSG00000128609 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 7 123536997-123558255 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043175 Supported Expressed in all thyroid gland: 249.5 -FEZF1 ZNF312B ENSG00000128610 FEZ family zinc finger 1 7 122301394-122310691 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA064639, HPA073693 Approved Supported Nucleus
Cytosol Tissue enriched 40 testis: 7.2 adipose tissue: 0.1 -OPN1SW BCP, BOP, CBT ENSG00000128617 Opsin 1 (cone pigments), short-wave-sensitive 7 128772491-128775790 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013562, HPA014083 Supported Mixed smooth muscle: 14.7 -MRPS12 RPMS12, RPS12, RPSM12 ENSG00000128626 Mitochondrial ribosomal protein S12 19 38930548-38933162 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046775, HPA050633 Uncertain Expressed in all duodenum: 12.3 -MYO1B myr1 ENSG00000128641 Myosin IB 2 191245185-191425389 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013607, HPA060144 Approved Validated Plasma membrane Mixed liver: 130.2 -HOXD1 HOX4, HOX4G ENSG00000128645 Homeobox D1 2 176188579-176190907 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA040062, HPA056900 Supported Nucleoplasm Tissue enhanced 0 epididymis: 8.6;fallopian tube: 7.4 lung: 4.6 -HOXD3 HOX1D, HOX4, HOX4A ENSG00000128652 Homeobox D3 2 176136612-176173102 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA051831, HPA063671 Validated Nucleoplasm
Nuclear bodies Tissue enriched 6 epididymis: 45.8 fallopian tube: 8.1 -MTX2 ENSG00000128654 Metaxin 2 2 176269395-176338025 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031550, HPA031551, HPA031552 Approved Approved Supported Nucleoli
Mitochondria Expressed in all testis: 115.8 -PDE11A ENSG00000128655 Phosphodiesterase 11A 2 177623252-178108339 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034560 Uncertain Tissue enhanced 0 epididymis: 14.2;parathyroid gland: 10.3 prostate: 8.5 -CHN1 ARHGAP2, CHN, DURS2, n-chimerin, RhoGAP2 ENSG00000128656 Chimerin 1 2 174799363-175005369 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036111 Approved Cytosol Group enriched 7 cerebral cortex: 640.9;parathyroid gland: 131.0 placenta: 55.5 -GAD1 GAD ENSG00000128683 Glutamate decarboxylase 1 (brain, 67kDa) 2 170813213-170861151 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004415, HPA031949, HPA058412, CAB078176 Supported Supported Approved Vesicles Tissue enriched 6 cerebral cortex: 75.5 parathyroid gland: 11.7 -OSGEPL1 Qri7 ENSG00000128694 O-sialoglycoprotein endopeptidase-like 1 2 189746660-189763227 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030693 Uncertain Validated Mitochondria Mixed testis: 12.2 -ORMDL1 ENSG00000128699 ORMDL sphingolipid biosynthesis regulator 1 2 189770323-189784371 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065643 Supported Endoplasmic reticulum Expressed in all epididymis: 153.1 -HAT1 KAT1 ENSG00000128708 Histone acetyltransferase 1 2 171922448-171983682 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036788, CAB037191 Supported Validated Nucleoplasm Expressed in all lymph node: 57.0 -HOXD9 HOX4, HOX4C ENSG00000128709 Homeobox D9 2 176122720-176124937 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068683 Supported Nucleus
Nucleoli Tissue enhanced 0 endometrium: 45.3 smooth muscle: 23.6 -HOXD10 HOX4, HOX4D ENSG00000128710 Homeobox D10 2 176108790-176119942 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA065871 Approved Nucleoplasm
Cytosol
Cytoplasmic bodies Tissue enhanced 0 endometrium: 48.0;smooth muscle: 24.9 kidney: 12.6 -HOXD11 HOX4, HOX4F ENSG00000128713 Homeobox D11 2 176104216-176109754 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA055155 Approved Nucleoplasm Tissue enhanced 0 endometrium: 5.9 smooth muscle: 1.6 -HOXD13 HOX4I, SPD ENSG00000128714 Homeobox D13 2 176092891-176095938 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064064 Supported Nucleus Group enriched 8 cervix, uterine: 7.9;colon: 5.1;prostate: 18.4;rectum: 9.6;seminal vesicle: 24.4 urinary bladder: 1.6 -HERC2 D15F37S1, jdf2, p528 ENSG00000128731 HECT and RLD domain containing E3 ubiquitin protein ligase 2 15 28111040-28322152 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017188, HPA048389 Approved Approved Vesicles Mixed parathyroid gland: 11.9 -SNRPN HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN ENSG00000128739 Small nuclear ribonucleoprotein polypeptide N 15 24823637-24978723 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA003482, HPA067842 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 516.6 -PSMG2 CLAST3, HCCA3, HsT1707, MDS003, MGC15092, PAC2, TNFSF5IP1 ENSG00000128789 Proteasome (prosome, macropain) assembly chaperone 2 18 12658043-12725740 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041517, HPA046741 Uncertain Approved Nucleus
Nuclear bodies Expressed in all testis: 171.5 -TWSG1 TSG ENSG00000128791 Twisted gastrulation BMP signaling modulator 1 18 9334767-9402420 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014898 Uncertain Approved Centrosome
Cytosol Expressed in all smooth muscle: 115.0 -ARHGAP22 RhoGAP2 ENSG00000128805 Rho GTPase activating protein 22 10 48446034-48656265 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020696, HPA040391, HPA064439 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Mixed cerebral cortex: 8.0 -WDFY4 C10orf64, Em:AC060234.3, FLJ45748, KIAA1607 ENSG00000128815 WDFY family member 4 10 48684876-48982956 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040634 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 lymph node: 47.7;spleen: 34.4;tonsil: 33.0 appendix: 23.7 -EIF2AK4 GCN2, KIAA1338 ENSG00000128829 Eukaryotic translation initiation factor 2 alpha kinase 4 15 39934146-40035591 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011811 Approved Approved Cytosol Expressed in all endometrium: 61.5 -MYO5C MGC74969 ENSG00000128833 Myosin VC 15 52192322-52295798 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020790, HPA032115, HPA032116 Supported Supported Nucleus
Cytosol Mixed parathyroid gland: 38.0 -CGNL1 FLJ14957, JACOP, KIAA1749, paracingulin ENSG00000128849 Cingulin-like 1 15 57375967-57550727 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013500, HPA056911, HPA069214 Supported Approved Cell Junctions Mixed kidney: 72.7 -TMOD2 NTMOD ENSG00000128872 Tropomodulin 2 (neuronal) 15 51751561-51816368 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041365 Supported Approved Nucleus
Nucleoli fibrillar center Tissue enriched 10 cerebral cortex: 111.3 seminal vesicle: 11.6 -TTBK2 KIAA0847, SCA11 ENSG00000128881 Tau tubulin kinase 2 15 42738734-42920809 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018113, HPA049866 Approved Uncertain Intermediate filaments Tissue enhanced 0 testis: 60.7 cerebral cortex: 16.7 -ELL3 FLJ22637 ENSG00000128886 Elongation factor RNA polymerase II-like 3 15 43772600-43777543 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028938 Uncertain Supported Nucleoplasm
Nucleoli Tissue enhanced 0 testis: 9.8 lymph node: 4.3 -C15orf57 CCDC32, MGC20481 ENSG00000128891 Chromosome 15 open reading frame 57 15 40528683-40565057 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041688 Uncertain Approved Nuclear speckles
Vesicles Expressed in all thyroid gland: 35.3 -INO80 hINO80, Ino80, INO80A, INOC1, KIAA1259 ENSG00000128908 INO80 complex subunit 15 40978880-41116354 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041417, HPA041484 Validated Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 17.9 -ICE2 BRCC1, FLJ11896, NARG2 ENSG00000128915 Interactor of little elongation complex ELL subunit 2 15 60419609-60479160 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040058 Supported Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 52.9 -DLL4 ENSG00000128917 Delta-like 4 (Drosophila) 15 40929340-40939072 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA023392 Uncertain Tissue enhanced 0 placenta: 28.4 lung: 16.4 -ALDH1A2 RALDH2 ENSG00000128918 Aldehyde dehydrogenase 1 family, member A2 15 57953424-58497866 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010022 Approved Tissue enhanced 0 endometrium: 117.2;fallopian tube: 107.1 testis: 96.5 -FAM63B KIAA1164 ENSG00000128923 Family with sequence similarity 63, member B 15 58771192-58861900 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051103, HPA063669 Approved Validated Nucleoplasm Mixed thyroid gland: 16.2 -IVD ACAD2 ENSG00000128928 Isovaleryl-CoA dehydrogenase 15 40405795-40435947 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041391, HPA044250 Supported Validated Nucleoplasm
Mitochondria Expressed in all thyroid gland: 151.3 -KNSTRN C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1 ENSG00000128944 Kinetochore-localized astrin/SPAG5 binding protein 15 40382721-40394246 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042027 Approved Supported Microtubules
Cytosol Tissue enhanced 0 testis: 113.2 thyroid gland: 63.9 -DUT dUTPase ENSG00000128951 Deoxyuridine triphosphatase 15 48331011-48343373 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054422, HPA060360 Supported Supported Nucleoplasm Expressed in all lymph node: 116.0 -CHAC1 MGC4504 ENSG00000128965 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 15 40952962-40956519 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042708, HPA043505 Approved Supported Mitochondria Tissue enhanced 0 esophagus: 25.6 pancreas: 14.5 -CLN6 FLJ20561, HsT18960, nclf ENSG00000128973 Ceroid-lipofuscinosis, neuronal 6, late infantile, variant 15 68206992-68257211 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066046, HPA074162 Approved Approved Vesicles Expressed in all appendix: 23.0 -ARPP19 ARPP-16, ARPP-19, ARPP16, ENSAL ENSG00000128989 CAMP-regulated phosphoprotein, 19kDa 15 52547045-52569883 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056851 Approved Expressed in all cerebral cortex: 512.0 -VPS13C FLJ10381, FLJ20136, KIAA1421 ENSG00000129003 Vacuolar protein sorting 13 homolog C (S. cerevisiae) 15 61852389-62060473 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043507 Uncertain Approved Microtubules Expressed in all parathyroid gland: 26.9 -CALML4 MGC4809, NY-BR-20 ENSG00000129007 Calmodulin-like 4 15 68190705-68206110 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051109 Supported Approved Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced 0 duodenum: 82.7;small intestine: 76.5 colon: 58.6 -ISLR HsT17563 ENSG00000129009 Immunoglobulin superfamily containing leucine-rich repeat 15 74173671-74176872 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040326, HPA050811 Approved Approved Golgi apparatus
Plasma membrane Mixed endometrium: 198.5 -THAP10 ENSG00000129028 THAP domain containing 10 15 70881342-70892785 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041416 Uncertain Approved Nucleoplasm
Cytosol Mixed cerebral cortex: 10.0 -LOXL1 LOL, LOXL ENSG00000129038 Lysyl oxidase-like 1 15 73925989-73952137 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042111, HPA063583 Approved Approved Endoplasmic reticulum Mixed seminal vesicle: 16.4 -ACKR4 CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1 ENSG00000129048 Atypical chemokine receptor 4 3 132597237-132618967 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA027595 Uncertain Cytosol Mixed duodenum: 19.7 -ANAPC13 APC13, DKFZP566D193, SWM1 ENSG00000129055 Anaphase promoting complex subunit 13 3 134477706-134486716 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046114 Uncertain Approved Mitochondria
Cytosol Expressed in all thyroid gland: 154.5 -MBD4 MED1 ENSG00000129071 Methyl-CpG binding domain 4 DNA glycosylase 3 129430944-129440179 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002031 Supported Supported Nuclear speckles Expressed in all lymph node: 77.5 -COPB1 COPB ENSG00000129083 Coatomer protein complex, subunit beta 1 11 14443440-14500027 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012338, HPA043954, HPA064403 Supported Validated Golgi apparatus
Vesicles
Cytosol Expressed in all thyroid gland: 131.9 -PSMA1 HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30 ENSG00000129084 Proteasome subunit alpha 1 11 14504874-14643635 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033765, HPA037646, HPA043891 Supported Validated Nucleoplasm Expressed in all placenta: 120.0 -SUMF2 DKFZp566I1024 ENSG00000129103 Sulfatase modifying factor 2 7 56064002-56080670 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024040, CAB025743, HPA074892 Supported Uncertain Vesicles
Plasma membrane Expressed in all fallopian tube: 159.3 -PALLD CGI-151, KIAA0992, SIH002 ENSG00000129116 Palladin, cytoskeletal associated protein 4 168497066-168928457 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035905 Supported Plasma membrane
Actin filaments
Cytosol Mixed endometrium: 441.6 -SPCS3 FLJ22649, PRO3567, SPC22/23, SPC3, YLR066W ENSG00000129128 Signal peptidase complex subunit 3 4 176319964-176332245 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053180 Approved Expressed in all thyroid gland: 103.8 -BBOX1 BBH, BBOX, G-BBH, gamma-BBH ENSG00000129151 Butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 11 27040725-27127809 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007600, HPA027823 Supported Approved Tissue enriched 7 kidney: 469.2 liver: 66.0 -MYOD1 bHLHc1, MYF3, MYOD, PUM ENSG00000129152 Myogenic differentiation 1 11 17719568-17722131 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA051362 Supported Nucleoplasm
Nuclear bodies
Cytosol Tissue enriched 12 skeletal muscle: 9.0 prostate: 0.7 -SERGEF DelGEF, Gnefr ENSG00000129158 Secretion regulating guanine nucleotide exchange factor 11 17788048-18013162 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037811, HPA037812, HPA074086 Supported Validated Nucleoplasm
Vesicles
Cytosol Expressed in all thyroid gland: 52.7 -KCNC1 Kv3.1 ENSG00000129159 Potassium channel, voltage gated Shaw related subfamily C, member 1 11 17734812-17783055 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047634, HPA048249 Supported Approved Nucleus
Nuclear membrane
Vesicles
Cytosol Tissue enriched 8 cerebral cortex: 16.5 testis: 1.9 -TPH1 TPH, TPRH ENSG00000129167 Tryptophan hydroxylase 1 11 18017564-18042426 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB010767, HPA022483 Supported Uncertain Cytosol Group enriched 6 colon: 9.0;duodenum: 10.5;rectum: 21.3;small intestine: 12.9;stomach: 15.5 prostate: 2.2 -CSRP3 CLP, CMD1M, MLP ENSG00000129170 Cysteine and glycine-rich protein 3 (cardiac LIM protein) 11 19182030-19210573 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042581 Supported Group enriched 25 heart muscle: 1401.7;skeletal muscle: 468.0 esophagus: 37.1 -E2F8 FLJ23311 ENSG00000129173 E2F transcription factor 8 11 19224063-19241620 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064882 Supported Nucleus
Nucleoli
Cytosol Mixed bone marrow: 9.2 -DCTD ENSG00000129187 DCMP deaminase 4 182890060-182917936 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035894 Approved Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 166.5 -SOX15 SOX20, SOX26, SOX27 ENSG00000129194 SRY (sex determining region Y)-box 15 17 7588178-7590170 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067196, HPA074049 Supported Supported Nucleus
Nucleoli
Golgi apparatus
Vesicles Tissue enhanced 0 skin: 40.6 esophagus: 17.5 -FAM64A CATS, FLJ10156, FLJ10491, RCS1 ENSG00000129195 Family with sequence similarity 64, member A 17 6444415-6451469 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043783, HPA049934 Uncertain Validated Nucleus
Nucleoli
Cytosol Mixed spleen: 6.6 -RPAIN hRIP, MGC4189, RIP ENSG00000129197 RPA interacting protein 17 5419641-5432876 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023924, HPA031526 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all cerebral cortex: 26.7 -USP6 HRP1, Tre-2, TRE17, Tre2, TRESMCR ENSG00000129204 Ubiquitin specific peptidase 6 17 5116438-5175034 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046969 Uncertain Uncertain Vesicles Tissue enhanced 0 testis: 17.8 skeletal muscle: 7.5 -SHBG ABP, MGC126834, MGC138391, TEBG ENSG00000129214 Sex hormone-binding globulin 17 7613946-7633383 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 liver: 32.9;testis: 13.8 small intestine: 7.6 -PLD2 ENSG00000129219 Phospholipase D2 17 4807096-4823434 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013397 Approved Expressed in all esophagus: 42.6 -AIPL1 LCA4 ENSG00000129221 Aryl hydrocarbon receptor interacting protein-like 1 17 6393693-6435199 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026578 Supported Not detected testis: 0.9 -CD68 DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1 ENSG00000129226 CD68 molecule 17 7579467-7582113 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000051, CAB000066, HPA048982, CAB072861, CAB072862 Supported Supported Golgi apparatus
Vesicles Expressed in all lung: 534.2 -TXNDC17 MGC14353, TRP14, TXNL5 ENSG00000129235 Thioredoxin domain containing 17 17 6640758-6644541 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022931 Approved Expressed in all esophagus: 70.2 -ATP1B2 AMOG ENSG00000129244 ATPase, Na+/K+ transporting, beta 2 polypeptide 17 7646627-7657768 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010698 Supported Tissue enriched 9 cerebral cortex: 340.3 ovary: 36.6 -FXR2 FMR1L2 ENSG00000129245 Fragile X mental retardation, autosomal homolog 2 17 7591230-7614871 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011205, HPA022997 Supported Supported Cytosol Expressed in all parathyroid gland: 43.9 -KIF1C SAX2, SPAX2, SPG58 ENSG00000129250 Kinesin family member 1C 17 4997948-5028401 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024602, HPA045020 Approved Expressed in all skeletal muscle: 193.6 -MPDU1 CDGIf, Lec35, PQLC5, SL15 ENSG00000129255 Mannose-P-dolichol utilization defect 1 17 7583529-7592789 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014845 Uncertain Supported Endoplasmic reticulum
Mitochondria Expressed in all rectum: 70.2 -PHF20L1 CGI-72, FLJ13649, FLJ21615, MGC64923, TDRD20B ENSG00000129292 PHD finger protein 20-like 1 8 132775358-132848807 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025060, HPA028417 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all thyroid gland: 37.9 -LRRC6 CILD19, LRTP, TSLRP ENSG00000129295 Leucine rich repeat containing 6 8 132571953-132675617 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028058 Approved Tissue enhanced 0 fallopian tube: 30.9;testis: 46.6 kidney: 12.5 -CCNT1 CCNT, CYCT1, HIVE1 ENSG00000129315 Cyclin T1 12 48688458-48716998 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004892, CAB009016 Supported Validated Nucleoplasm Expressed in all testis: 19.8 -PUS7L DKFZP434G1415 ENSG00000129317 Pseudouridylate synthase 7-like 12 43718993-43758817 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056203, HPA058750 Uncertain Supported Nuclear speckles Mixed parathyroid gland: 9.6 -KRI1 FLJ12949 ENSG00000129347 KRI1 homolog 19 10553078-10566037 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043110, HPA043574 Approved Validated Nucleoli Expressed in all appendix: 27.6 -ILF3 DRBP76, MPHOSPH4, MPP4, NF90, NFAR-1 ENSG00000129351 Interleukin enhancer binding factor 3, 90kDa 19 10654261-10692417 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001897 Supported Supported Nucleoplasm
Nucleoli
Mitochondria Expressed in all testis: 149.2 -SLC44A2 CTL2 ENSG00000129353 Solute carrier family 44 (choline transporter), member 2 19 10602457-10644559 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003228, HPA070799 Approved Approved Vesicles
Cell Junctions Expressed in all placenta: 224.3 -AP1M2 AP1-mu2, HSMU1B, mu2 ENSG00000129354 Adaptor-related protein complex 1, mu 2 subunit 19 10572671-10587315 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054999 Supported Vesicles Mixed thyroid gland: 98.0 -CDKN2D INK4D, p19 ENSG00000129355 Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 19 10566462-10569059 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011201, HPA043546 Supported Supported Nucleoplasm
Cytosol Tissue enhanced 0 bone marrow: 181.4 cerebral cortex: 61.5 -MTUS1 ATBP, ATIP1, DKFZp586D1519, FLJ14295, ICIS, KIAA1288, MP44, MTSG1 ENSG00000129422 Microtubule associated tumor suppressor 1 8 17643795-17800917 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067903, HPA069795 Validated Nucleoli
Microtubules Mixed parathyroid gland: 125.8 -KLK14 KLK-L6 ENSG00000129437 Kallikrein-related peptidase 14 19 51077495-51084245 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB026228 Uncertain Tissue enriched 5 skin: 10.3 breast: 2.0 -SIGLEC9 CD329 ENSG00000129450 Sialic acid binding Ig-like lectin 9 19 51124908-51136651 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010682 Uncertain Tissue enhanced 0 appendix: 25.4;spleen: 24.1 lung: 12.2 -KLK10 NES1, PRSSL1 ENSG00000129451 Kallikrein-related peptidase 10 19 51012739-51020175 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017195 Uncertain Plasma membrane
Cytosol Tissue enhanced 0 esophagus: 138.7;skin: 52.8 tonsil: 47.4 -KLK8 HNP, neuropsin, ovasin, PRSS19, TADG14 ENSG00000129455 Kallikrein-related peptidase 8 19 50996007-51002711 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019393, HPA035761 Supported Approved Vesicles Group enriched 6 esophagus: 78.1;fallopian tube: 20.6;skin: 97.0 breast: 10.9 -NGDN C14orf120, DKFZP564O092, LCP5, lpd-2, NGD ENSG00000129460 Neuroguidin, EIF4E binding protein 14 23469688-23509862 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000944 Approved Approved Nucleus
Nucleoli
Mitochondria Expressed in all endometrium: 54.8 -RIPK3 RIP3 ENSG00000129465 Receptor-interacting serine-threonine kinase 3 14 24336021-24340045 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055087 Uncertain Mixed small intestine: 25.6 -ADCY4 AC4 ENSG00000129467 Adenylate cyclase 4 14 24318349-24335093 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB005070, HPA048344 Approved Tissue enhanced 0 placenta: 20.9 lung: 11.6 -RAB2B FLJ14824 ENSG00000129472 RAB2B, member RAS oncogene family 14 21459020-21476973 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050292 Uncertain Expressed in all epididymis: 22.5 -BCL2L2 BCL-W, KIAA0271, PPP1R51 ENSG00000129473 BCL2-like 2 14 23298790-23311759 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level CAB040539 Approved Expressed in all cerebral cortex: 89.1 -AJUBA JUB, MGC15563 ENSG00000129474 Ajuba LIM protein 14 22971174-22982642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006171 Approved Approved Nucleus
Golgi apparatus Tissue enhanced 0 skin: 73.9 placenta: 27.9 -DTD2 C14orf126, MGC9912 ENSG00000129480 D-tyrosyl-tRNA deacylase 2 (putative) 14 31446036-31457510 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA001117 Approved Approved Vesicles Mixed cerebral cortex: 10.9 -PARP2 ADPRTL2 ENSG00000129484 Poly (ADP-ribose) polymerase 2 14 20343582-20357905 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052003 Approved Approved Nucleus
Nucleoli Expressed in all cerebral cortex: 46.5 -HEATR5A C14orf125, DKFZP434I1735 ENSG00000129493 HEAT repeat containing 5A 14 31291791-31420582 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049539 Uncertain Expressed in all parathyroid gland: 17.9 -FOXA1 HNF3A ENSG00000129514 Forkhead box A1 14 37589984-37596059 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011595, HPA050505 Supported Supported Nucleoplasm
Nucleoli fibrillar center Tissue enhanced 0 prostate: 145.4 breast: 36.3 -SNX6 ENSG00000129515 Sorting nexin 6 14 34561094-34630183 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049374 Approved Supported Endosomes
Lysosomes Expressed in all parathyroid gland: 216.6 -EAPP BM036, C14orf11, FLJ20578 ENSG00000129518 E2F-associated phosphoprotein 14 34515929-34539711 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002916 Approved Approved Nucleus
Golgi apparatus
Cytosol Expressed in all thyroid gland: 74.6 -EGLN3 HIFPH3, PHD3 ENSG00000129521 Egl-9 family hypoxia-inducible factor 3 14 33924231-34462774 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA064895 Approved Cytosol Tissue enhanced 0 skin: 98.2 heart muscle: 58.6 -MIS18BP1 C14orf106, FLJ11186, KIAA1903, KNL2, M18BP1 ENSG00000129534 MIS18 binding protein 1 14 45203190-45253540 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006504 Approved Approved Nucleoli
Cytosol Mixed lymph node: 26.3 -NRL D14S46E, NRL-MAF, RP27 ENSG00000129535 Neural retina leucine zipper 14 24080107-24115014 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026066, HPA064599 Supported Supported Nucleoplasm
Cytosol Mixed parathyroid gland: 4.1 -RNASE1 RAC1, RNS1 ENSG00000129538 Ribonuclease, RNase A family, 1 (pancreatic) 14 20801228-20803278 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001140 Supported Approved Nucleoplasm
Vesicles Expressed in all pancreas: 1947.0 -NEDD8 Nedd-8 ENSG00000129559 Neural precursor cell expressed, developmentally down-regulated 8 14 24216852-24232454 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004082 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 548.6 -DAD1 OST2 ENSG00000129562 Defender against cell death 1 14 22564905-22589269 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028882 Uncertain Approved Cytosol Expressed in all epididymis: 507.2 -TEP1 p240, TLP1, TP1, TROVE1, VAULT2 ENSG00000129566 Telomerase-associated protein 1 14 20365667-20413429 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029206 Supported Nucleoplasm
Vesicles Mixed parathyroid gland: 46.0 -EPB41L4A NBL4 ENSG00000129595 Erythrocyte membrane protein band 4.1 like 4A 5 112142441-112419316 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036580 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all parathyroid gland: 26.9 -CDO1 ENSG00000129596 Cysteine dioxygenase type 1 5 115804733-115816954 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036573, HPA057503 Supported Uncertain Nucleoplasm Tissue enhanced 0 epididymis: 135.2;liver: 209.6 adipose tissue: 103.7 -REEP5 C5orf18, D5S346, DP1, TB2 ENSG00000129625 Receptor accessory protein 5 5 112876379-112922539 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003895, HPA069960 Approved Approved Endoplasmic reticulum Expressed in all thyroid gland: 341.6 -ITFG1 CDA08, LNKN-1, TIP ENSG00000129636 Integrin alpha FG-GAP repeat containing 1 16 47154387-47464149 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015590, HPA019728 Approved Approved Intermediate filaments
Aggresome Expressed in all parathyroid gland: 108.2 -QRICH2 DKFZP434P0316 ENSG00000129646 Glutamine rich 2 17 76274049-76307680 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA021935, HPA052219 Uncertain Approved Nucleoplasm
Nuclear membrane
Vesicles Tissue enriched 10 testis: 22.2 fallopian tube: 2.2 -FOXJ1 FKHL13, HFH-4, HFH4 ENSG00000129654 Forkhead box J1 17 76136333-76141299 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA005714 Supported Tissue enriched 8 fallopian tube: 82.8 lung: 10.4 -SEC14L1 PRELID4A, SEC14L ENSG00000129657 SEC14-like lipid binding 1 17 77086716-77217101 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021463, HPA028703 Approved Approved Nucleoplasm
Cytosol Expressed in all placenta: 118.5 -RHBDF2 FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG ENSG00000129667 Rhomboid 5 homolog 2 (Drosophila) 17 76470891-76501790 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018080 Uncertain Expressed in all appendix: 51.0 -AANAT SNAT ENSG00000129673 Aralkylamine N-acetyltransferase 17 76453351-76470117 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054321 Approved Cytosol Tissue enhanced 0 testis: 4.8 appendix: 2.3 -ARHGEF6 alpha-PIX, alphaPIX, Cool-2, Cool2, KIAA0006, MRX46 ENSG00000129675 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 X 136665547-136782088 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003578 Approved Approved Cytosol Mixed placenta: 62.7 -MAP7D3 FLJ12649 ENSG00000129680 MAP7 domain containing 3 X 136213220-136256482 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035598, HPA058101 Approved Validated Centrosome Mixed testis: 29.9 -FGF13 FGF2, FHF2 ENSG00000129682 Fibroblast growth factor 13 X 138614731-139222777 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002809 Approved Supported Cytosol Tissue enhanced 0 parathyroid gland: 106.5 cerebral cortex: 47.7 -ASH2L ASH2, ASH2L1, ASH2L2, Bre2 ENSG00000129691 Ash2 (absent, small, or homeotic)-like (Drosophila) 8 38105242-38144076 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042289 Approved Supported Nucleoplasm
Plasma membrane Expressed in all testis: 74.5 -TTI2 C8orf41, FLJ23263 ENSG00000129696 TELO2 interacting protein 2 8 33473386-33513601 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023523, HPA029823 Approved Validated Centrosome Mixed testis: 21.9 -ART1 ART2, CD296 ENSG00000129744 ADP-ribosyltransferase 1 11 3645128-3664416 CD markers, Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051148 Uncertain Tissue enriched 21 skeletal muscle: 16.4 esophagus: 0.7 -CHRNA10 ENSG00000129749 Cholinergic receptor, nicotinic, alpha 10 (neuronal) 11 3665587-3671384 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 17 skeletal muscle: 16.6 lung: 0.9 -CDKN1C BWCR, BWS, KIP2, P57 ENSG00000129757 Cyclin-dependent kinase inhibitor 1C (p57, Kip2) 11 2883213-2885881 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002924 Supported Approved Nucleoplasm
Nuclear bodies
Cytosol Tissue enhanced 0 placenta: 202.0 adipose tissue: 62.4 -SGOL1 NY-BR-85 ENSG00000129810 Shugoshin-like 1 (S. pombe) 3 20160593-20186292 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069857 Supported Tissue enhanced 0 testis: 13.2 lymph node: 8.2 -RPS4Y1 MGC119100, MGC5070, RPS4Y, S4 ENSG00000129824 Ribosomal protein S4, Y-linked 1 Y 2841486-2932000 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000857 Approved Mixed prostate: 441.0 -VCY1B BPY1B ENSG00000129862 Variable charge, Y-linked 1B Y 14056217-14056958 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044996, HPA049357 Supported Tissue enriched 73 testis: 27.2 placenta: 0.3 -VCY BPY1, VCY1, VCY1A ENSG00000129864 Variable charge, Y-linked Y 13985772-13986513 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044996, HPA049357 Supported Tissue enriched 73 testis: 27.2 placenta: 0.3 -CDY2B CDY ENSG00000129873 Chromodomain protein, Y-linked, 2B Y 17877410-17880220 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.2 -CDH15 CDH14, CDH3 ENSG00000129910 Cadherin 15, type 1, M-cadherin (myotubule) 16 89171767-89195492 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009139, HPA070961 Supported Supported Golgi apparatus
Cytosol Tissue enriched 11 skeletal muscle: 13.0 placenta: 1.1 -KLF16 BTEB4, DRRF, NSLP2 ENSG00000129911 Kruppel-like factor 16 19 1852399-1863568 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052481 Approved Supported Nucleus Mixed cerebral cortex: 17.6 -TMEM8A M83, TMEM6, TMEM8 ENSG00000129925 Transmembrane protein 8A 16 370773-387113 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051281, HPA064673 Approved Supported Nucleoplasm
Cytokinetic bridge Expressed in all testis: 57.6 -DOHH HLRC1, MGC4293 ENSG00000129932 Deoxyhypusine hydroxylase/monooxygenase 19 3490821-3500940 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041953 Approved Approved Nucleus
Cytosol Mixed duodenum: 18.3 -MAU2 KIAA0892, mau-2, MAU2L, MGC75361, SCC4 ENSG00000129933 MAU2 sister chromatid cohesion factor 19 19320681-19358755 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059897 Supported Nucleoplasm Expressed in all testis: 25.6 -SHC2 SCK, SHCB, SLI ENSG00000129946 SHC (Src homology 2 domain containing) transforming protein 2 19 416583-460996 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006136 Approved Approved Cytosol Mixed cerebral cortex: 18.7 -PLPPR3 FLJ11535, LPPR3, PRG-2, PRG2 ENSG00000129951 Phospholipid phosphatase related 3 19 812488-821977 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052293, HPA057034 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced 0 bone marrow: 6.1;cerebral cortex: 9.6;fallopian tube: 8.8 testis: 2.1 -INS-IGF2 ENSG00000129965 INS-IGF2 readthrough 11 2132538-2161209 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB019430 Supported Group enriched 5 pancreas: 1.6;placenta: 4.6 endometrium: 0.5 -ABHD17A C19orf27, FAM108A1, MGC5244 ENSG00000129968 Abhydrolase domain containing 17A 19 1876810-1885547 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043270, HPA047226 Uncertain Approved Vesicles Mixed cerebral cortex: 31.5 -LBP BPIFD2 ENSG00000129988 Lipopolysaccharide binding protein 20 38346356-38377023 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001508, CAB025905 Approved Group enriched 5 adipose tissue: 68.5;liver: 264.3 appendix: 31.9 -SYT5 ENSG00000129990 Synaptotagmin V 19 55171199-55180441 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 10 cerebral cortex: 131.7 adrenal gland: 12.8 -TNNI3 CMD2A, CMH7, TNNC1 ENSG00000129991 Troponin I type 3 (cardiac) 19 55151767-55157773 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009349, HPA046428 Supported Approved Vesicles
Cytosol Tissue enriched 158 heart muscle: 3237.3 breast: 20.4 -CBFA2T3 MTG16, MTGR2, ZMYND4 ENSG00000129993 Core-binding factor, runt domain, alpha subunit 2; translocated to, 3 16 88874858-88977204 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059931, HPA062423, HPA065890 Approved Validated Nucleoplasm Tissue enhanced 0 spleen: 19.1 lymph node: 10.6 -GAMT PIG2, TP53I2 ENSG00000130005 Guanidinoacetate N-methyltransferase 19 1397084-1401570 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051806 Approved Expressed in all skeletal muscle: 400.4 -PUDP DXF68S1E, FAM16AX, GS1, HDHD1, HDHD1A ENSG00000130021 Pseudouridine 5'-phosphatase X 7048920-7148190 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all fallopian tube: 31.1 -ERMARD C6orf70, dJ266L20.3, FLJ11152 ENSG00000130023 ER membrane-associated RNA degradation 6 169751622-169781584 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041741 Approved Approved Cytosol Expressed in all testis: 33.0 -PHF10 BAF45a, FLJ10975, XAP135 ENSG00000130024 PHD finger protein 10 6 169703905-169725566 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055649 Supported Supported Nucleus Expressed in all parathyroid gland: 106.6 -PRRG3 TMG3 ENSG00000130032 Proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) X 151695124-151705924 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA060566 Uncertain Tissue enhanced 0 cerebral cortex: 8.9 cervix: 7.5 -GALNT8 GALNAC-T8 ENSG00000130035 Polypeptide N-acetylgalactosaminyltransferase 8 12 4720341-4851927 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA012638, HPA014418, HPA073461 Approved Approved Vesicles Group enriched 7 cerebral cortex: 19.5;colon: 18.0;duodenum: 8.4;rectum: 41.3;small intestine: 19.3;testis: 26.3 appendix: 3.3 -KCNA5 HK2, HPCN1, Kv1.5 ENSG00000130037 Potassium channel, voltage gated shaker related subfamily A, member 5 12 5043989-5046788 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021516, CAB022562 Approved Tissue enhanced 0 heart muscle: 20.8 esophagus: 5.6 -CRACR2A EFCAB4B, MGC4266 ENSG00000130038 Calcium release activated channel regulator 2A 12 3606633-3764819 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038685, HPA038686 Approved Mixed salivary gland: 15.2 -NXNL2 C9orf121 ENSG00000130045 Nucleoredoxin-like 2 9 88535101-88584274 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045526 Uncertain Approved Cytosol Mixed adipose tissue: 8.1 -STARD8 ARHGAP38, KIAA0189 ENSG00000130052 StAR-related lipid transfer (START) domain containing 8 X 68647666-68725842 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060788 Uncertain Mixed adipose tissue: 14.8 -FAM155B CXorf63, TED, TMEM28 ENSG00000130054 Family with sequence similarity 155, member B X 69505241-69532508 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036093 Uncertain Tissue enhanced 0 heart muscle: 12.9;seminal vesicle: 8.5;thyroid gland: 16.6 cerebral cortex: 2.5 -GDPD2 FLJ20207, GDE3, OBDPF ENSG00000130055 Glycerophosphodiester phosphodiesterase domain containing 2 X 70423031-70433390 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 50.9;spleen: 61.0 small intestine: 20.5 -SAT1 SAT, SSAT ENSG00000130066 Spermidine/spermine N1-acetyltransferase 1 X 23783173-23786226 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB047343, HPA055312 Approved Expressed in all thyroid gland: 1264.0 -GNL3L FLJ10613 ENSG00000130119 Guanine nucleotide binding protein-like 3 (nucleolar)-like X 54530211-54561071 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036314, HPA036315 Supported Supported Nucleus
Nucleoli
Cytosol Expressed in all thyroid gland: 16.4 -SH3BP4 ENSG00000130147 SH3-domain binding protein 4 2 234951973-235055714 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037533, HPA037534 Uncertain Mixed breast: 42.9 -MOSPD2 MGC26706 ENSG00000130150 Motile sperm domain containing 2 X 14873441-14922327 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003334 Uncertain Approved Endoplasmic reticulum Mixed skin: 29.1 -DOCK6 KIAA1395, ZIR1 ENSG00000130158 Dedicator of cytokinesis 6 19 11199295-11262481 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049423, HPA049424 Approved Supported Cytosol Mixed skin: 29.4 -ECSIT SITPEC ENSG00000130159 ECSIT signalling integrator 19 11505916-11529174 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042979 Approved Supported Nucleoplasm
Cytosol Expressed in all heart muscle: 53.9 -LDLR LDLCQ2 ENSG00000130164 Low density lipoprotein receptor 19 11089362-11133816 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009647, HPA013159 Approved Expressed in all lung: 87.7 -ELOF1 ELF1, MGC4549 ENSG00000130165 ELF1 homolog, elongation factor 1 19 11551147-11559236 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA045606 Uncertain Approved Cytosol Expressed in all testis: 164.8 -TSPAN16 TM-8, TM4-B, TM4SF16 ENSG00000130167 Tetraspanin 16 19 11296139-11326996 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041579 Approved Tissue enriched 32 testis: 153.1 bone marrow: 4.8 -C19orf80 ANGPTL8, RIFL, TD26 ENSG00000130173 Chromosome 19 open reading frame 80 19 11237450-11241943 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042131 Approved Nucleoplasm
Golgi apparatus Group enriched 17 adipose tissue: 13.8;liver: 63.5 epididymis: 2.2 -PRKCSH G19P1, PCLD, PLD1 ENSG00000130175 Protein kinase C substrate 80K-H 19 11435288-11450968 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004465, HPA041940, HPA043560 Supported Validated Endoplasmic reticulum Expressed in all ovary: 236.9 -CNN1 Sm-Calp, SMCC ENSG00000130176 Calponin 1, basic, smooth muscle 19 11538717-11550323 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000007, HPA014263 Supported Approved Actin filaments Tissue enhanced 0 seminal vesicle: 2086.6;smooth muscle: 3071.6 endometrium: 1724.7 -CDC16 ANAPC6, APC6, CUT9 ENSG00000130177 Cell division cycle 16 13 114234887-114272723 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042826 Approved Expressed in all testis: 83.4 -ZSCAN10 ZNF206 ENSG00000130182 Zinc finger and SCAN domain containing 10 16 3088890-3099317 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Not detected skin: 0.6 -THEM6 C8orf55, DSCD75 ENSG00000130193 Thioesterase superfamily member 6 8 142727203-142736927 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023255 Uncertain Approved Nuclear speckles
Cytosol Expressed in all thyroid gland: 18.4 -EXOC3L2 FLJ36147, XTP7 ENSG00000130201 Exocyst complex component 3-like 2 19 45212621-45234211 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041595, HPA061110 Approved Approved Nucleus
Vesicles Mixed spleen: 13.5 -PVRL2 CD112, HVEB, PRR2, PVRR2 ENSG00000130202 Poliovirus receptor-related 2 (herpesvirus entry mediator B) 19 44846175-44889228 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012759, CAB026138, HPA073459 Supported Uncertain Nucleoli fibrillar center
Cell Junctions Expressed in all placenta: 111.0 -APOE AD2 ENSG00000130203 Apolipoprotein E 19 44905754-44909393 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008363, HPA065539, HPA068768, CAB069921 Supported Approved Vesicles Expressed in all adrenal gland: 1810.4 -TOMM40 C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40 ENSG00000130204 Translocase of outer mitochondrial membrane 40 homolog (yeast) 19 44890569-44903689 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036231, HPA036232 Supported Validated Mitochondria
Cytosol Expressed in all appendix: 35.2 -APOC1 ENSG00000130208 Apolipoprotein C-I 19 44914247-44919349 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051518 Supported Tissue enriched 6 liver: 7217.4 adrenal gland: 1118.5 -GADD45G CR6, DDIT2, GADD45gamma, GRP17 ENSG00000130222 Growth arrest and DNA-damage-inducible, gamma 9 89605013-89606555 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023606 Approved Approved Nucleus Mixed adrenal gland: 47.4 -LRCH2 KIAA1495 ENSG00000130224 Leucine-rich repeats and calponin homology (CH) domain containing 2 X 115110616-115234072 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA003233 Approved Approved Nucleoli
Plasma membrane Mixed prostate: 13.3 -DPP6 DPPX ENSG00000130226 Dipeptidyl-peptidase 6 7 153887097-154894285 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050509 Supported Supported Tissue enhanced 0 cerebral cortex: 51.2;endometrium: 27.4 smooth muscle: 15.2 -XPO7 KIAA0745, RANBP16 ENSG00000130227 Exportin 7 8 21919671-22006585 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043727, HPA048153 Uncertain Approved Nucleus Expressed in all parathyroid gland: 77.3 -ACE2 ENSG00000130234 Angiotensin I converting enzyme 2 X 15561033-15602148 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000288, CAB026174 Supported Group enriched 6 duodenum: 186.1;gallbladder: 100.6;kidney: 93.3;small intestine: 266.6;testis: 92.6 heart muscle: 23.1 -FAM98C FLJ44669 ENSG00000130244 Family with sequence similarity 98, member C 19 38403135-38409088 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040930, HPA041730 Approved Approved Nucleus
Nucleoli
Cytosol Mixed small intestine: 15.5 -SAFB2 KIAA0138 ENSG00000130254 Scaffold attachment factor B2 19 5586999-5624046 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050894 Approved Supported Nucleoplasm
Nuclear bodies
Vesicles Expressed in all ovary: 40.2 -RPL36 DKFZp566B023, L36 ENSG00000130255 Ribosomal protein L36 19 5674947-5691876 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047153 Supported Uncertain Endoplasmic reticulum
Cytosol Expressed in all ovary: 2366.8 -ATP8B3 ATPIK ENSG00000130270 ATPase, aminophospholipid transporter, class I, type 8B, member 3 19 1782075-1812276 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 7 testis: 28.7 bone marrow: 4.0 -GDF1 ENSG00000130283 Growth differentiation factor 1 19 18868545-18896096 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 7 cerebral cortex: 12.3 testis: 1.7 -NCAN CSPG3 ENSG00000130287 Neurocan 19 19211973-19252233 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036814 Supported Uncertain Vesicles
Centrosome Tissue enriched 101 cerebral cortex: 183.9 testis: 1.8 -KIF1A ATSV, C2orf20, SPG30, UNC104 ENSG00000130294 Kinesin family member 1A 2 240713764-240820308 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005442 Approved Approved Cytosol Tissue enriched 13 cerebral cortex: 308.0 adrenal gland: 23.1 -GTPBP3 FLJ14700, GTPBG3, MSS1, MTGP1, THDF1 ENSG00000130299 GTP binding protein 3 (mitochondrial) 19 17334920-17342735 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042158 Approved Supported Mitochondria Expressed in all skin: 12.4 -PLVAP FELS, gp68, PV-1, PV1 ENSG00000130300 Plasmalemma vesicle associated protein 19 17351448-17377350 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA002279 Supported Uncertain Cytosol Expressed in all thyroid gland: 328.6 -BST2 CD317, tetherin ENSG00000130303 Bone marrow stromal cell antigen 2 19 17402939-17405648 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017060 Approved Supported Golgi apparatus
Plasma membrane
Cytosol Expressed in all ovary: 585.6 -SLC27A1 ACSVL5, FATP, FATP1, FLJ00336, MGC71751 ENSG00000130304 Solute carrier family 27 (fatty acid transporter), member 1 19 17468769-17506168 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed parathyroid gland: 34.3 -NSUN5 FLJ10267, NOL1R, NSUN5A, p120(NOL1), WBSCR20, WBSCR20A, Ynl022cL ENSG00000130305 NOP2/Sun domain family, member 5 7 73302517-73308867 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020536, HPA045590, HPA046867 Approved Validated Nucleus
Nucleoli Expressed in all bone marrow: 26.0 -USHBP1 AIEBP, FLJ38709, MCC2 ENSG00000130307 Usher syndrome 1C binding protein 1 19 17249176-17282786 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052471 Uncertain Mixed placenta: 8.7 -COLGALT1 FLJ22329, GLT25D1 ENSG00000130309 Collagen beta(1-O)galactosyltransferase 1 19 17555594-17583162 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047821 Approved Approved Vesicles Expressed in all placenta: 57.6 -DDA1 C19orf58, MGC2594, PCIA1 ENSG00000130311 DET1 and DDB1 associated 1 19 17309518-17323301 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042134, HPA055272 Approved Approved Nucleus
Nucleoli Expressed in all cerebral cortex: 11.6 -MRPL34 L34mt, MGC24974, MGC2633 ENSG00000130312 Mitochondrial ribosomal protein L34 19 17292609-17306843 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049276 Uncertain Expressed in all adrenal gland: 76.4 -PGLS 6PGL ENSG00000130313 6-phosphogluconolactonase 19 17511629-17521288 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040744, HPA042032 Approved Supported Nucleoplasm
Cytosol Expressed in all fallopian tube: 46.2 -LSM7 YNL147W ENSG00000130332 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated 19 2321517-2328620 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041850 Uncertain Approved Nucleoli fibrillar center Expressed in all lymph node: 72.1 -TULP4 KIAA1397, TUSP ENSG00000130338 Tubby like protein 4 6 158232236-158511828 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA005445 Approved Mixed cerebral cortex: 12.6 -SNX9 SDP1, SH3PX1, SH3PXD3A ENSG00000130340 Sorting nexin 9 6 157700387-157945077 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031410, HPA057203 Approved Validated Plasma membrane
Cytosol Expressed in all gallbladder: 71.1 -RTN4IP1 NIMP ENSG00000130347 Reticulon 4 interacting protein 1 6 106571971-106629487 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036357 Approved Mixed parathyroid gland: 11.2 -QRSL1 DKFZP564C1278, FLJ10989, FLJ12189, FLJ13447, GatA ENSG00000130348 Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 6 106629578-106668417 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029585, HPA029587 Approved Approved Vesicles
Centrosome Expressed in all lymph node: 18.9 -C6orf203 HSPC230, PRED31 ENSG00000130349 Chromosome 6 open reading frame 203 6 107028213-107051342 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049535 Approved Expressed in all adrenal gland: 47.8 -RSPH3 dJ111C20.1, RSHL2, RSP3 ENSG00000130363 Radial spoke 3 homolog (Chlamydomonas) 6 158972871-159000187 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039109, HPA040230 Approved Approved Vesicles
Plasma membrane
Cytosol Mixed parathyroid gland: 25.9 -MAS1 ENSG00000130368 MAS1 proto-oncogene, G protein-coupled receptor 6 159906690-159916530 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA013564 Uncertain Tissue enhanced 0 cerebral cortex: 1.8 cervix: 0.7 -ACSBG2 BGR, DKFZp434K1635, PRTD-NY3 ENSG00000130377 Acyl-CoA synthetase bubblegum family member 2 19 6135247-6193094 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043421, HPA051013 Supported Uncertain Cytosol Tissue enriched 709 testis: 291.8 cerebral cortex: 0.4 -MLLT1 ENL, LTG19, YEATS1 ENSG00000130382 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 19 6210379-6279948 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031166 Approved Supported Nucleoplasm Expressed in all placenta: 61.2 -FUT5 FUC-TV ENSG00000130383 Fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 19 5865826-5870540 Enzymes, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA046966 Uncertain Not detected testis: 0.3 -BMP15 GDF9B ENSG00000130385 Bone morphogenetic protein 15 X 50910784-50916607 Disease related genes, Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected fallopian tube: 0.3 -MLLT4 AF-6, AF6 ENSG00000130396 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 6 167826922-167972023 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868 Approved Validated Nucleoplasm
Plasma membrane
Cell Junctions Expressed in all esophagus: 111.1 -ACTN4 FSGS1 ENSG00000130402 Actinin, alpha 4 19 38647649-38731583 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001873, HPA006035 Supported Supported Nuclear bodies
Cytosol Expressed in all esophagus: 118.9 -STK33 ENSG00000130413 Serine/threonine kinase 33 11 8391868-8594289 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015742, HPA056855 Uncertain Approved Nucleus
Nucleoli
Cytosol Tissue enhanced 0 fallopian tube: 66.1;testis: 92.6 parathyroid gland: 42.5 -NDUFA10 CI-42k ENSG00000130414 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2 239892450-240025402 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059529 Supported Mitochondria Expressed in all heart muscle: 65.8 -EPO EP ENSG00000130427 Erythropoietin 7 100720800-100723700 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB010336 Supported Tissue enhanced 0 cervix, uterine: 2.0;endometrium: 1.7;liver: 1.7 prostate: 1.1 -ARPC1B ARC41, p40-ARC, p41-ARC ENSG00000130429 Actin related protein 2/3 complex, subunit 1B, 41kDa 7 99374249-99394801 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004832 Approved Supported Vesicles
Cytosol Expressed in all spleen: 259.0 -CACNG6 ENSG00000130433 Calcium channel, voltage-dependent, gamma subunit 6 19 53992288-54012669 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056615 Approved Nucleoli fibrillar center
Cytosol Group enriched 11 fallopian tube: 17.8;skeletal muscle: 33.9 lung: 2.3 -ZSWIM6 KIAA1577 ENSG00000130449 Zinc finger, SWIM-type containing 6 5 61332273-61546170 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035938 Uncertain Approved Cytosol Mixed parathyroid gland: 16.7 -FCHO1 KIAA0290 ENSG00000130475 FCH domain only 1 19 17747718-17788568 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041653, HPA062981 Approved Validated Nucleoplasm
Cytosol Tissue enhanced 0 lymph node: 29.2 spleen: 20.5 -UNC13A KIAA1032, Munc13-1 ENSG00000130477 Unc-13 homolog A (C. elegans) 19 17601328-17688365 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041418 Uncertain Tissue enriched 16 cerebral cortex: 53.7 adrenal gland: 3.4 -MAP1S BPY2IP1, C19orf5, FLJ10669, MAP8, VCY2IP1 ENSG00000130479 Microtubule-associated protein 1S 19 17719242-17734516 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050934, HPA054637 Approved Validated Cytosol Expressed in all testis: 29.6 -KLHDC7B MGC16635 ENSG00000130487 Kelch domain containing 7B 22 50548033-50551023 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000518 Uncertain Tissue enhanced 0 parathyroid gland: 12.5 thyroid gland: 3.4 -SCO2 MYP6, SCO1L ENSG00000130489 SCO2 cytochrome c oxidase assembly protein 22 50523568-50526439 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056254 Approved Supported Nucleoplasm
Mitochondria Expressed in all appendix: 50.4 -PXDN D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN ENSG00000130508 Peroxidasin 2 1631887-1744852 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012375 Approved Tissue enhanced 0 smooth muscle: 86.1 adipose tissue: 66.6 -SSBP4 ENSG00000130511 Single stranded DNA binding protein 4 19 18418864-18434562 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all spleen: 52.1 -GDF15 MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB ENSG00000130513 Growth differentiation factor 15 19 18374731-18389176 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011191, CAB062554 Supported Supported Golgi apparatus Tissue enhanced 0 placenta: 121.8 prostate: 63.1 -PGPEP1 Pcp, PGP, PGP-I, PGPI ENSG00000130517 Pyroglutamyl-peptidase I 19 18340587-18369950 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035368, HPA055277 Approved Approved Golgi apparatus Expressed in all kidney: 29.2 -KIAA1683 ENSG00000130518 KIAA1683 19 18257097-18274509 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042409 Supported Tissue enriched 6 testis: 34.5 endometrium: 5.5 -LSM4 YER112W ENSG00000130520 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated 19 18306230-18323274 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040932 Uncertain Approved Vesicles Expressed in all testis: 102.3 -JUND AP-1 ENSG00000130522 Jun D proto-oncogene 19 18279760-18281622 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005268, HPA063029 Supported Supported Nucleus Expressed in all bone marrow: 278.3 -HRC MGC133236 ENSG00000130528 Histidine rich calcium binding protein 19 49151198-49155424 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004833 Supported Group enriched 40 heart muscle: 361.3;skeletal muscle: 155.5 epididymis: 6.5 -TRPM4 FLJ20041 ENSG00000130529 Transient receptor potential cation channel, subfamily M, member 4 19 49157741-49211836 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041169 Supported Supported Nucleoplasm
Plasma membrane Mixed colon: 27.5 -OR11H1 OR22-1 ENSG00000130538 Olfactory receptor, family 11, subfamily H, member 1 22 15528158-15529139 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA047370 Uncertain Not detected epididymis: 0.0 -SULT4A1 hBR-STL-1, SULTX3 ENSG00000130540 Sulfotransferase family 4A, member 1 22 43824509-43862503 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003129 Supported Tissue enriched 35 cerebral cortex: 144.1 adrenal gland: 4.1 -ZNF557 MGC4054 ENSG00000130544 Zinc finger protein 557 19 7069444-7087968 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA003151, HPA029291 Uncertain Approved Nucleus
Intermediate filaments
Cytosol Mixed testis: 5.6 -CRB3 MGC17303 ENSG00000130545 Crumbs family member 3 19 6463777-6467221 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA013835 Approved Supported Cell Junctions Mixed duodenum: 38.4 -OLFM1 AMY, NOE1, NOELIN, OlfA ENSG00000130558 Olfactomedin 1 9 135075243-135121179 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057444 Uncertain Approved Nucleus
Nucleoli
Cytosol Tissue enriched 9 cerebral cortex: 732.4 epididymis: 85.0 -CAMSAP1 DKFZp434F195, FLJ31228 ENSG00000130559 Calmodulin regulated spectrin-associated protein 1 9 135808487-135907228 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020527, HPA024161 Approved Supported Mitotic spindle
Cytosol Expressed in all testis: 34.2 -UBAC1 GBDR1, UBADC1 ENSG00000130560 UBA domain containing 1 9 135932969-135961380 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005651 Approved Supported Golgi apparatus
Plasma membrane
Cytosol Expressed in all skeletal muscle: 88.7 -SAG ARRESTIN, RP47 ENSG00000130561 S-antigen; retina and pineal gland (arrestin) 2 233307816-233347055 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004946 Supported Tissue enhanced 0 testis: 1.8 epididymis: 0.9 -ZBTB46 BTBD4, BZEL, FLJ13502, RINZF, ZNF340 ENSG00000130584 Zinc finger and BTB domain containing 46 20 63743666-63831244 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA013997 Uncertain Approved Nucleus Mixed spleen: 13.8 -HELZ2 KIAA1769, PDIP1, PRIC285 ENSG00000130589 Helicase with zinc finger 2, transcriptional coactivator 20 63558086-63574239 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051267 Uncertain Mixed spleen: 15.5 -SAMD10 C20orf136 ENSG00000130590 Sterile alpha motif domain containing 10 20 63974113-63980008 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040973 Approved Approved Nucleoplasm Mixed lymph node: 7.7 -LSP1 WP34 ENSG00000130592 Lymphocyte-specific protein 1 11 1852970-1892267 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017781, HPA019693, HPA071843 Supported Supported Plasma membrane Expressed in all spleen: 286.5 -TNNT3 AMCD2B, DA2B, DKFZp779M2348, FSSV ENSG00000130595 Troponin T type 3 (skeletal, fast) 11 1919562-1938706 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002451, HPA037810, HPA056909 Supported Tissue enriched 72 skeletal muscle: 9595.3 esophagus: 133.5 -TNNI2 AMCD2B, DA2B, FSSV ENSG00000130598 Troponin I type 2 (skeletal, fast) 11 1838989-1841680 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018697, HPA055938 Supported Approved Nucleoplasm
Intermediate filaments Tissue enriched 38 skeletal muscle: 5538.3 esophagus: 145.5 -COL5A1 ENSG00000130635 Collagen, type V, alpha 1 9 134641774-134844843 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030769 Approved Approved Vesicles Mixed cervix: 157.1 -ATXN10 E46L, FLJ37990, SCA10 ENSG00000130638 Ataxin 10 22 45671798-45845307 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049531 Approved Supported Plasma membrane
Cytosol Expressed in all cerebral cortex: 83.7 -TUBGCP2 GCP2, SPBC97, Spc97p ENSG00000130640 Tubulin, gamma complex associated protein 2 10 133278630-133312337 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037885 Approved Supported Nucleoplasm
Centrosome Expressed in all fallopian tube: 31.8 -CALY CALCYON, DRD1IP, NSG3 ENSG00000130643 Calcyon neuron-specific vesicular protein 10 133324072-133336935 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042283 Uncertain Group enriched 13 adrenal gland: 23.6;cerebral cortex: 77.3 testis: 3.8 -CYP2E1 CYP2E ENSG00000130649 Cytochrome P450, family 2, subfamily E, polypeptide 1 10 133520406-133561220 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009128, HPA029564 Supported Tissue enriched 155 liver: 5312.8 tonsil: 34.3 -PNPLA7 C9orf111, FLJ31318, FLJ43070, FLJ44279, NTE-R1, NTEL1, RP11-48C7.2 ENSG00000130653 Patatin-like phospholipase domain containing 7 9 137459953-137550534 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA009130 Uncertain Uncertain Microtubule organizing center
Cytosol Mixed prostate: 15.7 -HBZ HBZ-T1, HBZ1 ENSG00000130656 Hemoglobin, zeta 16 152687-154503 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 12 bone marrow: 2.4;placenta: 1.0;testis: 3.9 skin: 0.2 -PAK4 ENSG00000130669 P21 protein (Cdc42/Rac)-activated kinase 4 19 39125770-39182816 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025747, CAB044670, HPA070175, HPA072220 Uncertain Supported Plasma membrane
Cell Junctions Expressed in all prostate: 42.2 -MNX1 HB9, HLXB9, HOXHB9, SCRA1 ENSG00000130675 Motor neuron and pancreas homeobox 1 7 156994051-157010651 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071717 Approved Nucleus
Nucleoli
Cytosol Tissue enhanced 0 duodenum: 7.5;small intestine: 6.8 colon: 3.8 -ZNF337 dJ694B14.1 ENSG00000130684 Zinc finger protein 337 20 25674215-25696841 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA044303, HPA064219 Uncertain Approved Nuclear speckles
Plasma membrane Expressed in all parathyroid gland: 28.7 -CEP85 CCDC21, DKFZP434L0117 ENSG00000130695 Centrosomal protein 85kDa 1 26234153-26279038 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028252 Approved Supported Nucleoli
Golgi apparatus
Cytosol Tissue enhanced 0 skeletal muscle: 34.1;testis: 44.1 heart muscle: 12.9 -TAF4 TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135 ENSG00000130699 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 20 61953469-62065810 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008599, CAB031484 Supported Supported Nucleoplasm
Cytosol Mixed testis: 6.6 -GATA5 bB379O24.1, GATAS ENSG00000130700 GATA binding protein 5 20 62463497-62475970 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA067583 Approved Nucleoplasm
Cytosol Tissue enhanced 0 duodenum: 11.7;small intestine: 11.3;testis: 8.8 stomach: 7.6 -RBBP8NL C20orf151, dJ908M14.3 ENSG00000130701 RBBP8 N-terminal like 20 62410237-62427533 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042627 Uncertain Tissue enhanced 0 small intestine: 5.3 duodenum: 4.6 -LAMA5 ENSG00000130702 Laminin, alpha 5 20 62307955-62367312 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054609, CAB078157 Supported Supported Nucleoplasm
Vesicles Tissue enhanced 0 skin: 42.2 placenta: 28.8 -OSBPL2 DFNA67, KIAA0772, ORP-2 ENSG00000130703 Oxysterol binding protein-like 2 20 62231922-62296213 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041127, HPA042659 Uncertain Approved Cytosol Expressed in all skin: 49.8 -ADRM1 ARM1, GP110, Rpn13 ENSG00000130706 Adhesion regulating molecule 1 20 62302093-62308862 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042266 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 108.8 -ASS1 ASS, CTLN1 ENSG00000130707 Argininosuccinate synthase 1 9 130444929-130501274 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020896, HPA020934 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 kidney: 1253.5;liver: 1027.3 fallopian tube: 258.7 -PRDM12 ENSG00000130711 PR domain containing 12 9 130664594-130682981 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043143 Uncertain Approved Nucleus Not detected cerebral cortex: 0.3 -EXOSC2 hRrp4p, p7, RRP4, Rrp4p ENSG00000130713 Exosome component 2 9 130693721-130704894 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021756, HPA021790 Approved Supported Nucleus
Nucleoli Expressed in all endometrium: 21.3 -POMT1 LGMD2K ENSG00000130714 Protein-O-mannosyltransferase 1 9 131502902-131523806 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065252 Approved Golgi apparatus Expressed in all testis: 62.7 -UCK1 FLJ12255, URK1 ENSG00000130717 Uridine-cytidine kinase 1 9 131523801-131531268 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050969 Approved Approved Nucleus Expressed in all thyroid gland: 31.1 -FIBCD1 FLJ14810 ENSG00000130720 Fibrinogen C domain containing 1 9 130902438-130939286 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053898, HPA055353 Uncertain Supported Cell Junctions Tissue enhanced 0 adrenal gland: 4.7;parathyroid gland: 8.5;testis: 5.3 cerebral cortex: 2.5 -PRRC2B BAT2L, BAT2L1, KIAA0515, LQFBS-1, MGC10526 ENSG00000130723 Proline-rich coiled-coil 2B 9 131394093-131500197 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021022, HPA064301 Uncertain Approved Nuclear bodies
Cytosol Expressed in all cerebral cortex: 133.4 -CHMP2A BC-2, CHMP2, VPS2, VPS2A ENSG00000130724 Charged multivesicular body protein 2A 19 58551566-58555124 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041153, HPA042031 Supported Approved Nucleus
Plasma membrane
Cytosol Expressed in all thyroid gland: 191.1 -UBE2M hUbc12, UBC12 ENSG00000130725 Ubiquitin-conjugating enzyme E2M 19 58555712-58558960 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004993, HPA054551, HPA057800 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all cerebral cortex: 108.3 -TRIM28 KAP1, PPP1R157, RNF96, TF1B, TIF1B ENSG00000130726 Tripartite motif containing 28 19 58544091-58550722 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010066, HPA064033 Supported Validated Nucleoplasm Expressed in all ovary: 215.6 -C16orf13 MGC13114 ENSG00000130731 Chromosome 16 open reading frame 13 16 634427-636366 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044004 Uncertain Expressed in all cerebral cortex: 43.1 -YIPF2 FinGER2, MGC3262 ENSG00000130733 Yip1 domain family, member 2 19 10922185-10928681 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019902 Approved Approved Golgi apparatus
Mitochondria Expressed in all testis: 73.3 -ATG4D APG4-D, APG4D, AUTL4 ENSG00000130734 Autophagy related 4D, cysteine peptidase 19 10543895-10553418 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA067683 Approved Expressed in all small intestine: 25.7 -EIF2S3 EIF2, EIF2G, EIF2gamma ENSG00000130741 Eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa X 24054716-24077971 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012471 Approved Expressed in all ovary: 179.1 -TMEM160 FLJ20512 ENSG00000130748 Transmembrane protein 160 19 47045907-47048630 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055904 Uncertain Mixed cerebral cortex: 21.0 -ZC3H4 C19orf7, KIAA1064 ENSG00000130749 Zinc finger CCCH-type containing 4 19 47064187-47113752 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040934, HPA041068 Supported Validated Nucleoplasm
Cytosol Expressed in all spleen: 13.8 -NPAS1 bHLHe11, MOP5, PASD5 ENSG00000130751 Neuronal PAS domain protein 1 19 47019820-47045775 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043364, HPA072259 Approved Approved Nucleoplasm Group enriched 5 cerebral cortex: 3.9;skin: 4.4;spleen: 1.9;stomach: 2.7 lymph node: 0.6 -GMFG ENSG00000130755 Glia maturation factor, gamma 19 39328353-39342372 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002954 Uncertain Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all spleen: 313.5 -MAP3K10 MEKK10, MLK2, MST ENSG00000130758 Mitogen-activated protein kinase kinase kinase 10 19 40191744-40215575 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA007039 Approved Approved Nucleus
Actin filaments
Cytosol Tissue enhanced 0 cerebral cortex: 31.2 testis: 7.1 -ARHGEF16 GEF16, NBR ENSG00000130762 Rho guanine nucleotide exchange factor (GEF) 16 1 3454426-3481113 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010609 Approved Tissue enhanced 0 duodenum: 43.3 small intestine: 36.6 -LRRC47 KIAA1185, RP1-286D6.3 ENSG00000130764 Leucine rich repeat containing 47 1 3778558-3796504 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008512, HPA012018 Supported Supported Nucleoli fibrillar center Expressed in all cerebral cortex: 19.8 -SESN2 DKFZp761M0212, HI95, SES2, SEST2 ENSG00000130766 Sestrin 2 1 28259527-28282491 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018191 Uncertain Approved Cytosol Mixed bone marrow: 25.7 -SMPDL3B ASML3B ENSG00000130768 Sphingomyelin phosphodiesterase, acid-like 3B 1 27934993-27959157 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030561 Approved Golgi apparatus
Cytosol Mixed rectum: 26.0 -ATPIF1 ATPI, ATPIP, IP, MGC1167, MGC8898 ENSG00000130770 ATPase inhibitory factor 1 1 28236109-28246906 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027999 Supported Validated Mitochondria Expressed in all heart muscle: 357.7 -MED18 FLJ20045, p28b ENSG00000130772 Mediator complex subunit 18 1 28329002-28335967 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027429 Uncertain Approved Nucleoplasm Expressed in all lymph node: 13.0 -THEMIS2 C1orf38, ICB-1 ENSG00000130775 Thymocyte selection associated family member 2 1 27872543-27886685 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031096, HPA031097 Uncertain Approved Golgi apparatus Tissue enhanced 0 bone marrow: 137.8 spleen: 119.4 -CLIP1 CLIP, CLIP-170, CLIP170, CYLN1, RSN ENSG00000130779 CAP-GLY domain containing linker protein 1 12 122271432-122422632 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004399, HPA026678 Approved Supported Microtubule ends
Cytosol Expressed in all parathyroid gland: 156.2 -CCDC62 CT109, ERAP75, FLJ40344, TSP-NY ENSG00000130783 Coiled-coil domain containing 62 12 122774327-122827528 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039021, HPA058741 Approved Approved Nucleoplasm
Plasma membrane Tissue enriched 143 testis: 115.3 spleen: 0.8 -HIP1R FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655 ENSG00000130787 Huntingtin interacting protein 1 related 12 122834453-122862960 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017187, HPA038135, HPA038136 Approved Validated Vesicles
Plasma membrane
Cytosol Expressed in all cerebral cortex: 53.3 -ZNF317 ENSG00000130803 Zinc finger protein 317 19 9140380-9163424 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042075, HPA048625 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 20.4 -PPAN BXDC3, SSF, SSF1, SSF2 ENSG00000130810 Peter pan homolog (Drosophila) 19 10106289-10111634 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA043265 Approved Expressed in all appendix: 20.7 -EIF3G eIF3-delta, eIF3-p44, eIF3g, EIF3S4 ENSG00000130811 Eukaryotic translation initiation factor 3, subunit G 19 10115017-10119918 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041997 Approved Validated Cytosol Expressed in all ovary: 217.5 -ANGPTL6 AGF, ARP5 ENSG00000130812 Angiopoietin-like 6 19 10092338-10102796 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 liver: 10.0 lymph node: 4.0 -C19orf66 FLJ11286 ENSG00000130813 Chromosome 19 open reading frame 66 19 10086122-10093252 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042001 Approved Mixed fallopian tube: 20.2 -DNMT1 CXXC9, DNMT, MCMT ENSG00000130816 DNA (cytosine-5-)-methyltransferase 1 19 10133345-10231286 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002694, CAB005876 Supported Validated Nucleoplasm Expressed in all placenta: 51.2 -ZNF426 MGC2663 ENSG00000130818 Zinc finger protein 426 19 9523224-9538627 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA029342 Approved Approved Nucleoplasm Mixed esophagus: 23.2 -SLC6A8 CRTR, CT1 ENSG00000130821 Solute carrier family 6 (neurotransmitter transporter), member 8 X 153688099-153696593 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed small intestine: 90.8 -PNCK CaMK1b, MGC45419 ENSG00000130822 Pregnancy up-regulated nonubiquitous CaM kinase X 153669730-153689010 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA007458 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 40.7;seminal vesicle: 51.7 smooth muscle: 22.1 -DKC1 DKC, dyskerin, NAP57, NOLA4, XAP101 ENSG00000130826 Dyskeratosis congenita 1, dyskerin X 154762742-154777689 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000166, HPA000447, HPA001022, CAB033086 Supported Supported Nucleus
Nucleoli fibrillar center Expressed in all lymph node: 45.7 -PLXNA3 6.3, Plxn3, PLXN4, SEX, XAP-6 ENSG00000130827 Plexin A3 X 154458281-154477779 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058989 Supported Vesicles
Plasma membrane
Cell Junctions Mixed skin: 12.1 -DUSP9 MKP-4, MKP4 ENSG00000130829 Dual specificity phosphatase 9 X 153642492-153651326 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003336 Supported Approved Endoplasmic reticulum Group enriched 35 kidney: 28.9;placenta: 102.9 testis: 1.8 -MPP1 DXS552E, PEMP ENSG00000130830 Membrane protein, palmitoylated 1, 55kDa X 154778684-154821007 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000167 Approved Nucleoli
Nuclear speckles
Cytosol Expressed in all placenta: 118.7 -ZNF331 RITA, ZNF361, ZNF463 ENSG00000130844 Zinc finger protein 331 19 53520981-53580269 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063157 Approved Nucleoplasm Expressed in all adrenal gland: 210.3 -ZNF236 ENSG00000130856 Zinc finger protein 236 18 76822607-76970727 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008600 Uncertain Approved Nucleoplasm
Cell Junctions
Cytosol Mixed testis: 13.2 -SLC7A10 asc-1 ENSG00000130876 Solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 19 33208664-33225850 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041884, HPA057036 Uncertain Uncertain Nucleus
Nucleoli Group enriched 23 adipose tissue: 31.5;cerebral cortex: 6.6 breast: 0.8 -LRP3 hLRp105, LRP-3 ENSG00000130881 Low density lipoprotein receptor-related protein 3 19 33177603-33208867 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed ovary: 63.4 -C12orf65 FLJ38663, SPG55 ENSG00000130921 Chromosome 12 open reading frame 65 12 123232916-123257959 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038194, HPA057595 Uncertain Approved Nucleus
Mitochondria
Cytosol Expressed in all testis: 26.7 -NOL11 DKFZP586L0724 ENSG00000130935 Nucleolar protein 11 17 67717833-67744531 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022010 Approved Validated Nucleoli Expressed in all parathyroid gland: 25.0 -UBE4B E4, KIAA0684, UBOX3, UFD2 ENSG00000130939 Ubiquitination factor E4B 1 10032832-10181239 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019219 Approved Expressed in all parathyroid gland: 42.7 -CASZ1 castor, cst, FLJ20321, SRG, ZNF693 ENSG00000130940 Castor zinc finger 1 1 10636604-10796650 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028222, HPA029927 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 skin: 26.9 prostate: 14.2 -PKDREJ ENSG00000130943 Polycystin (PKD) family receptor for egg jelly 22 46255663-46263355 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA034587 Supported Tissue enriched 9 testis: 6.2 skin: 0.7 -HSD17B3 SDR12C2 ENSG00000130948 Hydroxysteroid (17-beta) dehydrogenase 3 9 96235306-96302152 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056833 Supported Approved Vesicles Tissue enriched 15 testis: 74.6 thyroid gland: 4.8 -NUTM2F DKFZp434I1117, FAM22F ENSG00000130950 NUT family member 2F 9 94318196-94328644 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA064635 Uncertain Nuclear bodies Tissue enriched 12 testis: 1.2 adipose tissue: 0.0 -HABP4 IHABP4, SERBP1L ENSG00000130956 Hyaluronan binding protein 4 9 96450201-96491336 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055969 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 74.0 -FBP2 ENSG00000130957 Fructose-1,6-bisphosphatase 2 9 94558720-94593793 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012513, HPA055286 Approved Approved Nucleoplasm
Plasma membrane Tissue enriched 8 skeletal muscle: 266.1 stomach: 32.9 -SLC35D2 SQV7L, UGTrel8 ENSG00000130958 Solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 9 96320706-96383710 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA064047 Approved Validated Golgi apparatus Expressed in all small intestine: 73.8 -PRRG1 PRGP1 ENSG00000130962 Proline rich Gla (G-carboxyglutamic acid) 1 X 37349275-37457295 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056029, HPA078129 Uncertain Approved Vesicles
Plasma membrane Mixed cerebral cortex: 21.6 -UBA1 A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X ENSG00000130985 Ubiquitin-like modifier activating enzyme 1 X 47190861-47215128 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000289, HPA001506, CAB019435, CAB073410 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 235.0 -RGN RC, SMP30 ENSG00000130988 Regucalcin X 47078355-47093314 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029102, HPA029103 Supported Approved Nucleus Tissue enhanced 0 adrenal gland: 203.8;liver: 196.1 kidney: 56.6 -POLN ENSG00000130997 Polymerase (DNA directed) nu 4 2071918-2242121 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035939, HPA035940 Validated Nucleoplasm Tissue enhanced 0 adipose tissue: 3.0;testis: 4.4 prostate: 1.0 -PPIL4 ENSG00000131013 Peptidylprolyl isomerase (cyclophilin)-like 4 6 149504733-149546038 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031599, HPA031600 Approved Validated Nucleoplasm Expressed in all thyroid gland: 47.9 -ULBP2 RAET1H ENSG00000131015 UL16 binding protein 2 6 149942000-149949235 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018974 Approved Supported Vesicles
Plasma membrane Mixed esophagus: 3.0 -AKAP12 AKAP250, SSeCKS ENSG00000131016 A kinase (PRKA) anchor protein 12 6 151239999-151358557 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006344, CAB026379, HPA056230 Supported Supported Plasma membrane
Cytosol Expressed in all testis: 183.8 -SYNE1 8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B ENSG00000131018 Spectrin repeat containing, nuclear envelope 1 6 152121684-152637801 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019113 Approved Supported Nucleoplasm
Nuclear membrane Expressed in all parathyroid gland: 58.0 -ULBP3 RAET1N ENSG00000131019 UL16 binding protein 3 6 150063150-150069095 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056541, HPA063007 Uncertain Uncertain Vesicles
Microtubule organizing center Tissue enhanced 0 testis: 11.9;thyroid gland: 8.8 fallopian tube: 3.9 -LATS1 WARTS ENSG00000131023 Large tumor suppressor kinase 1 6 149658153-149718256 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031804 Approved Uncertain Nucleoplasm
Vesicles Expressed in all parathyroid gland: 23.2 -EPS8L1 DRC3, FLJ20258, MGC23164, MGC4642 ENSG00000131037 EPS8-like 1 19 55072020-55087923 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041851, HPA043545 Uncertain Supported Cytosol Tissue enhanced 0 skin: 18.5;stomach: 24.2 esophagus: 9.0 -LILRB2 CD85d, ILT4, LIR-2, LIR2, MIR-10, MIR10 ENSG00000131042 Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 19 54238904-54281184 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 9.9;bone marrow: 21.7;spleen: 10.7 lung: 4.2 -AAR2 bA234K24.2, C20orf4 ENSG00000131043 AAR2 splicing factor homolog 20 36236459-36270918 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034220, HPA048645 Uncertain Approved Cytosol Expressed in all smooth muscle: 41.5 -TTLL9 C20orf125, dJ310O13.1 ENSG00000131044 Tubulin tyrosine ligase-like family member 9 20 31870702-31944963 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041772, HPA055676 Uncertain Uncertain Nucleoplasm
Microtubules Tissue enhanced 0 fallopian tube: 6.4;testis: 5.8 epididymis: 2.8 -BPIFA2 bA49G10.1, C20orf70, PSP, SPLUNC2 ENSG00000131050 BPI fold containing family A, member 2 20 33161768-33181412 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044006 Supported Tissue enriched 531 salivary gland: 2674.5 epididymis: 5.0 -RBM39 CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2 ENSG00000131051 RNA binding motif protein 39 20 35703609-35742312 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001591 Supported Supported Nucleoplasm
Nuclear speckles
Microtubules
Microtubule organizing center Expressed in all bone marrow: 124.6 -COX4I2 COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2 ENSG00000131055 Cytochrome c oxidase subunit IV isoform 2 (lung) 20 31637888-31645006 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 lung: 42.8;placenta: 156.1 thyroid gland: 19.2 -BPIFA3 bA49G10.4, C20orf71, SPLUNC3 ENSG00000131059 BPI fold containing family A, member 3 20 33217310-33227758 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA062708 Supported Tissue enriched 533 testis: 53.2 adipose tissue: 0.0 -ZNF341 dJ553F4.3 ENSG00000131061 Zinc finger protein 341 20 33731657-33792269 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA023240, HPA024607, HPA067108 Uncertain Approved Nucleoplasm
Vesicles Mixed testis: 2.3 -GGT7 D20S101, dJ18C9.2, GGTL3, GGTL5 ENSG00000131067 Gamma-glutamyltransferase 7 20 34844720-34872860 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013204, HPA013339 Approved Approved Nucleus
Vesicles Expressed in all cerebral cortex: 50.1 -DEFB118 C20orf63, DEFB-18, dJ1018D12.3, ESC42 ENSG00000131068 Defensin, beta 118 20 31368618-31373923 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042634 Approved Tissue enriched 12100 epididymis: 1209.9 parathyroid gland: 0.0 -ACSS2 ACAS2, AceCS, ACS, ACSA, dJ1161H23.1 ENSG00000131069 Acyl-CoA synthetase short-chain family member 2 20 34872146-34927962 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004141 Approved Approved Nucleoplasm
Vesicles
Cytosol Mixed adipose tissue: 55.9 -EDA2R EDA-A2R, EDAA2R, TNFRSF27, XEDAR ENSG00000131080 Ectodysplasin A2 receptor X 66595637-66639298 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054522 Approved Cell Junctions Mixed thyroid gland: 9.5 -ARHGEF9 KIAA0424, PEM-2 ENSG00000131089 Cdc42 guanine nucleotide exchange factor (GEF) 9 X 63634967-63809274 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035419, HPA055291 Approved Supported Cytosol Expressed in all cerebral cortex: 91.1 -C1QL1 C1QRF, C1QTNF14, CRF ENSG00000131094 Complement component 1, q subcomponent-like 1 17 44959693-44968071 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 15 cerebral cortex: 38.5 duodenum: 2.5 -GFAP FLJ45472 ENSG00000131095 Glial fibrillary acidic protein 17 44905008-44916937 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000039, HPA056030, HPA063513 Supported Supported Supported Intermediate filaments Tissue enriched 431 cerebral cortex: 4111.0 bone marrow: 9.5 -PYY PYY1 ENSG00000131096 Peptide YY 17 43952738-44004469 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010973, CAB016734 Supported Group enriched 15 colon: 53.7;rectum: 39.9;small intestine: 27.8 duodenum: 2.6 -HIGD1B CLST11240, CLST11240-15 ENSG00000131097 HIG1 hypoxia inducible domain family, member 1B 17 44846353-44850480 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 6 lung: 55.6;placenta: 152.3 gallbladder: 18.2 -ATP6V1E1 ATP6E, ATP6E2, ATP6V1E, P31, Vma4 ENSG00000131100 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 22 17592136-17628818 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009528, CAB018699, HPA029196 Supported Approved Nucleoplasm Expressed in all cerebral cortex: 302.2 -ZNF227 ENSG00000131115 Zinc finger protein 227 19 44207547-44237268 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030573 Uncertain Approved Plasma membrane Expressed in all parathyroid gland: 18.4 -ZNF428 C19orf37, MGC51082, Zfp428 ENSG00000131116 Zinc finger protein 428 19 43607219-43619874 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042596, HPA048072 Uncertain Approved Nucleoli
Mitochondria Expressed in all cerebral cortex: 71.7 -TEX101 CT131, MGC4766, SGRG, SPATA44 ENSG00000131126 Testis expressed 101 19 43401496-43418597 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041915, HPA042513 Supported Tissue enriched 107 testis: 173.0 skin: 1.6 -ZNF141 D4S90, pHZ-44 ENSG00000131127 Zinc finger protein 141 4 337814-384864 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed adrenal gland: 15.0 -CCL25 Ckb15, SCYA25, TECK ENSG00000131142 Chemokine (C-C motif) ligand 25 19 8052767-8062650 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055883 Uncertain Group enriched 320 duodenum: 544.3;small intestine: 667.7 lymph node: 1.8 -COX4I1 COX4, COX4-1 ENSG00000131143 Cytochrome c oxidase subunit IV isoform 1 16 85798633-85807044 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002485, CAB004080 Supported Supported Mitochondria Expressed in all heart muscle: 1070.8 -EMC8 C16orf2, C16orf4, COX4NB, FAM158B, NOC4 ENSG00000131148 ER membrane protein complex subunit 8 16 85771758-85799608 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049476 Approved Supported Cytosol Expressed in all parathyroid gland: 17.1 -GSE1 KIAA0182 ENSG00000131149 Gse1 coiled-coil protein 16 85611409-85676204 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036365 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all parathyroid gland: 55.8 -RP11-178L8.4 ENSG00000131152 16 87302876-87334273 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA040850 Uncertain Mixed skeletal muscle: 1.6 -GINS2 Pfs2, PSF2 ENSG00000131153 GINS complex subunit 2 (Psf2 homolog) 16 85676198-85690073 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057285 Uncertain Supported Nucleoplasm Mixed testis: 12.2 -CHMP1A CHMP1, KIAA0047, PCOLN3, PRSM1, Vps46A ENSG00000131165 Charged multivesicular body protein 1A 16 89644431-89657845 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all small intestine: 53.1 -SH3BGRL MGC117402 ENSG00000131171 SH3 domain binding glutamate-rich protein like X 81201943-81298547 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051248 Approved Approved Vesicles Expressed in all seminal vesicle: 356.7 -COX7B ENSG00000131174 Cytochrome c oxidase subunit VIIb X 77899438-77907373 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058041 Uncertain Expressed in all heart muscle: 62.6 -SLC34A1 NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2 ENSG00000131183 Solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 5 177379235-177398848 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA051255 Approved Tissue enriched 164 kidney: 161.0 liver: 0.9 -F12 ENSG00000131187 Coagulation factor XII (Hageman factor) 5 177402140-177409576 Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003825 Approved Tissue enriched 78 liver: 141.7 bone marrow: 1.8 -PRR7 MGC10772 ENSG00000131188 Proline rich 7 (synaptic) 5 177446445-177456286 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046636 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 8.1 bone marrow: 3.7 -NFATC1 NF-ATC, NFAT2, NFATc ENSG00000131196 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 18 79395856-79529325 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004513, HPA071732 Supported Supported Nucleoplasm
Nuclear bodies Mixed lymph node: 25.0 -IDO1 IDO, INDO ENSG00000131203 Indoleamine 2,3-dioxygenase 1 8 39902275-39928444 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023072, HPA023149, HPA027772 Supported Tissue enhanced 0 placenta: 148.0 lymph node: 58.1 -GJA9 CX58, CX59, GJA10 ENSG00000131233 Gap junction protein, alpha 9, 59kDa 1 38874451-38881587 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA067850 Uncertain Tissue enhanced 0 testis: 2.2 skin: 0.5 -CAP1 CAP ENSG00000131236 CAP, adenylate cyclase-associated protein 1 (yeast) 1 40040233-40072649 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030124 Approved Supported Cytosol Expressed in all appendix: 429.7 -PPT1 CLN1, INCL, PPT ENSG00000131238 Palmitoyl-protein thioesterase 1 1 40072705-40097703 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021546 Supported Expressed in all spleen: 196.0 -RAB11FIP4 FLJ00131, KIAA1821, MGC11316, RAB11-FIP4 ENSG00000131242 RAB11 family interacting protein 4 (class II) 17 31391624-31538217 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021595, HPA063203 Approved Supported Vesicles Tissue enhanced 0 cerebral cortex: 68.1 testis: 42.4 -RLIM MGC15161, NY-REN-43, RNF12 ENSG00000131263 Ring finger protein, LIM domain interacting X 74585217-74614617 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018895 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 29.1 -CDX4 ENSG00000131264 Caudal type homeobox 4 X 73447254-73455245 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA056528 Uncertain Tissue enriched 8 skin: 1.3 seminal vesicle: 0.1 -ABCB7 ABC7, ASAT, Atm1p, EST140535 ENSG00000131269 ATP-binding cassette, sub-family B (MDR/TAP), member 7 X 75053172-75156732 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034982 Approved Supported Mitochondria Expressed in all parathyroid gland: 21.3 -TRAF3 CAP-1, CD40bp, CRAF1, LAP1 ENSG00000131323 TNF receptor-associated factor 3 14 102777476-102911500 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002933 Uncertain Mixed appendix: 26.5 -HAUS8 HICE1, MGC20533, NY-SAR-48 ENSG00000131351 HAUS augmin-like complex, subunit 8 19 17049729-17075625 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039406 Uncertain Mixed testis: 16.7 -ADGRE3 EMR3 ENSG00000131355 Adhesion G protein-coupled receptor E3 19 14619117-14690027 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015638 Uncertain Tissue enhanced 0 appendix: 8.9;spleen: 8.8 lung: 3.9 -MRPS25 DKFZp313H0817, FLJ00023, MRP-S25, RPMS25 ENSG00000131368 Mitochondrial ribosomal protein S25 3 15042460-15065335 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043490 Approved Validated Mitochondria Expressed in all testis: 33.1 -SH3BP5 Sab ENSG00000131370 SH3-domain binding protein 5 (BTK-associated) 3 15254853-15341368 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036445, HPA057988 Uncertain Supported Nucleoplasm
Nuclear bodies Expressed in all adrenal gland: 222.2 -HACL1 2-HPCL, HPCL, PHYH2 ENSG00000131373 2-hydroxyacyl-CoA lyase 1 3 15560704-15601852 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035496, HPA035497, HPA073760 Approved Supported Vesicles Expressed in all duodenum: 52.3 -TBC1D5 KIAA0210 ENSG00000131374 TBC1 domain family, member 5 3 17157162-18444817 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035125, HPA035126 Uncertain Supported Golgi apparatus
Vesicles Expressed in all parathyroid gland: 55.9 -CAPN7 PalBH ENSG00000131375 Calpain 7 3 15206152-15252918 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046617 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all thyroid gland: 39.2 -RFTN1 FLJ23866, KIAA0084, MIG2, Raftlin ENSG00000131378 Raftlin, lipid raft linker 1 3 16313574-16514026 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048725 Approved Mixed lymph node: 137.1 -C3orf20 DKFZP434N1817 ENSG00000131379 Chromosome 3 open reading frame 20 3 14675099-14773034 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039584 Uncertain Tissue enriched 28 testis: 10.3 tonsil: 0.3 -RBSN ZFYVE20 ENSG00000131381 Rabenosyn, RAB effector 3 15070073-15099163 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044878 Approved Validated Vesicles Expressed in all cerebral cortex: 30.8 -GALNT15 GALNT7, GALNTL2, pp-GalNAc-T15 ENSG00000131386 Polypeptide N-acetylgalactosaminyltransferase 15 3 16174649-16231992 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA017076, HPA051551 Uncertain Approved Vesicles
Plasma membrane Tissue enhanced 0 adipose tissue: 36.2;cerebral cortex: 41.4;placenta: 42.6 breast: 18.3 -SLC6A6 TAUT ENSG00000131389 Solute carrier family 6 (neurotransmitter transporter), member 6 3 14402576-14489349 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015028, HPA016488 Supported Approved Cell Junctions
Cytosol Mixed ovary: 50.7 -KCNC3 Kv3.3, SCA13 ENSG00000131398 Potassium channel, voltage gated Shaw related subfamily C, member 3 19 50311937-50333515 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA018041 Uncertain Tissue enhanced 0 parathyroid gland: 39.3 cerebral cortex: 19.9 -NAPSA KAP, Kdap, NAP1, NAPA ENSG00000131400 Napsin A aspartic peptidase 19 50358477-50365830 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009591, HPA045280, HPA047236, HPA047744 Supported Tissue enriched 14 lung: 1413.9 kidney: 100.6 -NR1H2 LXR-b, NER, NER-I, RIP15, UNR ENSG00000131408 Nuclear receptor subfamily 1, group H, member 2 19 50329653-50382982 Cancer-related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056838, HPA070212 Uncertain Approved Nucleoplasm Expressed in all bone marrow: 87.8 -LRRC4B DKFZp761A179, HSM, LRIG4 ENSG00000131409 Leucine rich repeat containing 4B 19 50516892-50568045 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058986 Uncertain Tissue enhanced 0 cerebral cortex: 61.6 cervix: 12.8 -PDLIM4 RIL ENSG00000131435 PDZ and LIM domain 4 5 132257671-132273454 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011912 Uncertain Approved Actin filaments
Cytosol Mixed smooth muscle: 61.2 -KIF3A FLA10, KLP-20 ENSG00000131437 Kinesin family member 3A 5 132692628-132737638 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037085 Approved Approved Nucleoplasm
Intermediate filaments
Cytosol Tissue enhanced 0 cerebral cortex: 83.0 testis: 43.8 -MGAT1 GLCNAC-TI, GLYT1, GNT-1, MGAT ENSG00000131446 Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 5 180784782-180815652 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017432 Approved Expressed in all spleen: 120.7 -GFPT2 GFAT2 ENSG00000131459 Glutamine-fructose-6-phosphate transaminase 2 5 180300690-180353387 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056892, HPA059910 Uncertain Supported Vesicles Tissue enhanced 0 adipose tissue: 89.7 appendix: 26.2 -TUBG1 TUBG, TUBGCP1 ENSG00000131462 Tubulin, gamma 1 17 42609676-42615234 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004608 Approved Tissue enriched 6 testis: 242.4 smooth muscle: 39.7 -PSME3 Ki, PA28-gamma, PA28G, REG-GAMMA ENSG00000131467 Proteasome activator subunit 3 17 42824385-42843758 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008388, HPA012510 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 104.4 -RPL27 L27 ENSG00000131469 Ribosomal protein L27 17 42998273-43002959 Cancer-related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002649 Approved Expressed in all lymph node: 2459.3 -PSMC3IP GT198, Hop2, HUMGT198A, TBPIP ENSG00000131470 PSMC3 interacting protein 17 42572315-42577831 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044439 Approved Supported Nucleoplasm Tissue enhanced 0 testis: 31.1 fallopian tube: 8.0 -AOC3 HPAO, VAP-1, VAP1 ENSG00000131471 Amine oxidase, copper containing 3 17 42851184-42858130 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000980, CAB025797 Supported Approved Golgi apparatus
Cytosol Tissue enhanced 0 adipose tissue: 449.0 smooth muscle: 203.0 -ACLY ACL, ATPCL, CLATP ENSG00000131473 ATP citrate lyase 17 41866908-41930542 Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007783, HPA022434, HPA022953, HPA022959, HPA028758 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all prostate: 95.8 -VPS25 DERP9, EAP20, MGC10540 ENSG00000131475 Vacuolar protein sorting 25 homolog (S. cerevisiae) 17 42773436-42779599 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004978, HPA052217, HPA057284 Uncertain Approved Centrosome Expressed in all fallopian tube: 92.2 -RAMP2 ENSG00000131477 Receptor (G protein-coupled) activity modifying protein 2 17 42758447-42763041 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052020 Approved Vesicles Mixed lung: 179.1 -AOC2 DAO2, RAO ENSG00000131480 Amine oxidase, copper containing 2 (retina-specific) 17 42844600-42850707 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA057779 Uncertain Tissue enhanced 0 adipose tissue: 6.2;testis: 5.9 spleen: 1.2 -G6PC G6PT, GSD1a ENSG00000131482 Glucose-6-phosphatase, catalytic subunit 17 42900797-42913369 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052324 Approved Tissue enhanced 0 kidney: 88.4;liver: 146.8 small intestine: 33.8 -NDUFA2 B8 ENSG00000131495 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 5 140638740-140647785 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035933 Uncertain Expressed in all adrenal gland: 117.9 -ANKHD1 FLJ10042, FLJ11979, FLJ14127, FLJ20288, KIAA1085, MASK, MASK1 ENSG00000131503 Ankyrin repeat and KH domain containing 1 5 140401814-140539856 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008718 Approved Expressed in all parathyroid gland: 73.2 -DIAPH1 DFNA1, hDIA1, LFHL1 ENSG00000131504 Diaphanous-related formin 1 5 141515016-141619055 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004916, HPA076913 Approved Approved Plasma membrane Expressed in all lymph node: 73.7 -NDFIP1 MGC10924, N4WBP5 ENSG00000131507 Nedd4 family interacting protein 1 5 142108505-142154443 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009682 Approved Expressed in all cerebral cortex: 246.7 -UBE2D2 UBC4, UbcH5B ENSG00000131508 Ubiquitin-conjugating enzyme E2D 2 5 139526431-139628433 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003920 Approved Approved Plasma membrane
Cytosol Expressed in all testis: 237.4 -EXOC4 KIAA1699, MGC27170, SEC8, SEC8L1, Sec8p ENSG00000131558 Exocyst complex component 4 7 133253073-134066589 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031443, HPA031444 Approved Supported Nucleus
Nucleoli Expressed in all parathyroid gland: 50.0 -ACAP3 CENTB5, KIAA1716 ENSG00000131584 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 1 1292376-1309609 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049317, HPA058381 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all cerebral cortex: 26.6 -C1orf159 FLJ20584 ENSG00000131591 Chromosome 1 open reading frame 159 1 1081818-1116361 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA010019 Approved Approved Nucleoli fibrillar center
Cytosol Mixed skin: 15.2 -ANO1 DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A ENSG00000131620 Anoctamin 1, calcium activated chloride channel 11 70078302-70189528 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032148 Supported Tissue enhanced 0 epididymis: 217.7;seminal vesicle: 295.7 skin: 116.0 -PPFIA1 LIP.1, LIPRIN ENSG00000131626 Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 11 70270700-70384403 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008272, CAB017032, HPA042271 Uncertain Validated Focal adhesion sites
Cytosol Expressed in all testis: 56.9 -TMEM204 C16orf30, CLP24, FLJ20898 ENSG00000131634 Transmembrane protein 204 16 1528688-1555580 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014028 Approved Mixed adipose tissue: 40.6 -KREMEN2 KRM2, MGC10791 ENSG00000131650 Kringle containing transmembrane protein 2 16 2963944-2968383 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003223 Uncertain Approved Nucleoli Tissue enhanced 0 skin: 6.9 cerebral cortex: 2.1 -THOC6 fSAP35, MGC2655, WDR58 ENSG00000131652 THO complex 6 16 3024027-3027755 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052953 Uncertain Supported Nucleoplasm
Nuclear speckles Expressed in all skin: 29.3 -TRAF7 DKFZp586I021, MGC7807, RFWD1, RNF119 ENSG00000131653 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 16 2155698-2178129 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041229 Approved Supported Vesicles
Plasma membrane Expressed in all duodenum: 41.1 -BARX1 ENSG00000131668 BARX homeobox 1 9 93951622-93955372 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA055858 Approved Nucleoplasm
Vesicles Tissue enriched 7 stomach: 11.2 testis: 1.5 -NINJ1 NIN1 ENSG00000131669 Ninjurin 1 9 93121489-93134288 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045063 Uncertain Expressed in all bone marrow: 158.5 -CA6 ENSG00000131686 Carbonic anhydrase VI 1 8945867-8975092 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028550, HPA028692 Supported Tissue enriched 154 salivary gland: 3824.3 breast: 24.8 -NPHP4 KIAA0673, POC10, SLSN4 ENSG00000131697 Nephronophthisis 4 1 5862811-5992473 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065526 Approved Mixed fallopian tube: 12.4 -MAP1B MAP5, PPP1R102 ENSG00000131711 Microtubule-associated protein 1B 5 72107234-72209570 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009792, HPA022275 Supported Validated Cytosol Tissue enriched 5 cerebral cortex: 188.2 smooth muscle: 36.3 -RHOXF2 CT107, PEPP-2, PEPP2, THG1 ENSG00000131721 Rhox homeobox family, member 2 X 120158561-120165630 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003314, CAB020794 Supported Tissue enriched 155 testis: 20.7 epididymis: 0.1 -IL13RA1 CD213a1, IL-13Ra, NR4 ENSG00000131724 Interleukin 13 receptor, alpha 1 X 118727572-118794539 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000293, HPA001795 Approved Nucleoplasm
Golgi apparatus Expressed in all lung: 72.1 -WDR44 DKFZp686L20145, RAB11BP, RPH11 ENSG00000131725 WD repeat domain 44 X 118346073-118449961 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038084, HPA046719 Approved Supported Golgi apparatus Expressed in all parathyroid gland: 22.8 -CKMT2 SMTCK ENSG00000131730 Creatine kinase, mitochondrial 2 (sarcomeric) 5 81233285-81266397 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051880 Approved Group enriched 21 heart muscle: 672.7;skeletal muscle: 505.4 adrenal gland: 28.1 -ZCCHC9 DKFZp761J139, PPP1R41 ENSG00000131732 Zinc finger, CCHC domain containing 9 5 81301590-81313297 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038404, HPA057521 Uncertain Approved Intermediate filaments Expressed in all placenta: 27.3 -KRT34 Ha-4, KRTHA4 ENSG00000131737 Keratin 34, type I 17 41377650-41382403 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055194, HPA072208 Supported Approved Nucleus
Vesicles Tissue enriched 8 cervix, uterine: 4.2 testis: 0.5 -KRT33B Ha-3II, KRTHA3B ENSG00000131738 Keratin 33B, type I 17 41363494-41369800 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055194 Supported Not detected testis: 0.1 -TNS4 CTEN ENSG00000131746 Tensin 4 17 40475828-40501597 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skin: 66.8 esophagus: 31.8 -TOP2A TOP2 ENSG00000131747 Topoisomerase (DNA) II alpha 17 40388516-40417950 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002448, HPA006458, HPA026773 Supported Validated Nucleus
Nucleoli Tissue enhanced 0 testis: 108.0 lymph node: 48.2 -STARD3 es64, MLN64 ENSG00000131748 StAR-related lipid transfer (START) domain containing 3 17 39637065-39663484 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017021 Uncertain Expressed in all testis: 33.3 -RARA NR1B1, RAR ENSG00000131759 Retinoic acid receptor, alpha 17 40309192-40357643 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA058282 Supported Nucleus
Cytosol Expressed in all gallbladder: 68.9 -PPP1R1B DARPP-32, FLJ20940 ENSG00000131771 Protein phosphatase 1, regulatory (inhibitor) subunit 1B 17 39626740-39636626 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004026, HPA048630, HPA061142 Approved Approved Tissue enhanced 0 colon: 213.5;rectum: 223.8 salivary gland: 155.3 -KHDRBS3 Etle, etoile, SALP, SLM-2, SLM2, T-STAR ENSG00000131773 KH domain containing, RNA binding, signal transduction associated 3 8 135457457-135656722 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000275, HPA000500, HPA000981 Supported Supported Nucleoplasm Group enriched 7 cerebral cortex: 89.3;testis: 284.7 epididymis: 27.4 -CHD1L ALC1 ENSG00000131778 Chromodomain helicase DNA binding protein 1-like 1 147242641-147295766 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027789, HPA028670 Supported Supported Nucleoplasm Expressed in all testis: 48.1 -PEX11B ENSG00000131779 Peroxisomal biogenesis factor 11 beta 1 145911350-145918837 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050104 Supported Expressed in all cerebral cortex: 44.9 -FMO5 ENSG00000131781 Flavin containing monooxygenase 5 1 147175351-147243050 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012373 Supported Supported Endoplasmic reticulum
Cytosol Tissue enhanced 0 liver: 324.2 small intestine: 77.0 -PIAS3 FLJ14651, ZMIZ5 ENSG00000131788 Protein inhibitor of activated STAT, 3 1 145848522-145859836 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006389, HPA067383 Approved Supported Nucleoplasm Expressed in all fallopian tube: 59.4 -PRKAB2 ENSG00000131791 Protein kinase, AMP-activated, beta 2 non-catalytic subunit 1 147155106-147172550 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044342 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 44.8 -FSHB ENSG00000131808 Follicle stimulating hormone, beta polypeptide 11 30231016-30235261 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB023410, HPA069703 Supported Not detected epididymis: 0.0 -PDHA1 PDHA ENSG00000131828 Pyruvate dehydrogenase (lipoamide) alpha 1 X 19343893-19361705 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047487, HPA047864, HPA063053 Approved Supported Mitochondria Expressed in all heart muscle: 231.0 -RAI2 ENSG00000131831 Retinoic acid induced 2 X 17800049-17861337 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051054 Uncertain Approved Plasma membrane Mixed fallopian tube: 78.2 -MCCC2 MCCB ENSG00000131844 Methylcrotonoyl-CoA carboxylase 2 (beta) 5 71587288-71658704 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038300, HPA038301, HPA061546 Supported Validated Mitochondria Expressed in all prostate: 75.0 -ZNF304 ENSG00000131845 Zinc finger protein 304 19 57351307-57359898 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA050531 Approved Approved Nuclear speckles Mixed parathyroid gland: 15.6 -ZSCAN5A MGC4161, ZNF495, ZSCAN5 ENSG00000131848 Zinc finger and SCAN domain containing 5A 19 56219670-56368383 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041263, HPA043123, HPA046836, HPA060667 Uncertain Uncertain Nuclear speckles Tissue enhanced 0 testis: 34.3 fallopian tube: 11.3 -ZNF132 pHZ-12 ENSG00000131849 Zinc finger protein 132 19 58432814-58440222 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008726 Uncertain Approved Vesicles
Intermediate filaments Mixed parathyroid gland: 10.6 -USP29 ENSG00000131864 Ubiquitin specific peptidase 29 19 57119138-57131926 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021064 Uncertain Tissue enriched 5 testis: 9.1 skin: 1.7 -VIMP AD-015, MGC2553, SBBI8, SELS, SEPS1 ENSG00000131871 VCP-interacting membrane selenoprotein 15 101270817-101277500 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010025 Approved Validated Endoplasmic reticulum Expressed in all testis: 141.3 -CHSY1 CSS1, KIAA0990 ENSG00000131873 Chondroitin sulfate synthase 1 15 101175723-101251932 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048902 Uncertain Expressed in all placenta: 64.3 -SNRPA1 Lea1 ENSG00000131876 Small nuclear ribonucleoprotein polypeptide A' 15 101281510-101295282 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045622, HPA048499 Supported Validated Nuclear speckles Expressed in all testis: 68.2 -LLGL1 DLG4, HUGL, HUGL-1, LLGL ENSG00000131899 Lethal giant larvae homolog 1 (Drosophila) 17 18225587-18244875 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022924, HPA023569 Approved Tissue enhanced 0 cerebral cortex: 42.3 endometrium: 14.1 -NR0B2 SHP ENSG00000131910 Nuclear receptor subfamily 0, group B, member 2 1 26911489-26913966 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 duodenum: 80.8;liver: 48.6 small intestine: 29.6 -LIN28A CSDD1, FLJ12457, LIN-28, LIN28, ZCCHC1 ENSG00000131914 Lin-28 homolog A (C. elegans) 1 26410778-26429722 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB020785 Uncertain Uncertain Nucleoplasm Tissue enriched 10 testis: 4.3 epididymis: 0.4 -THAP1 4833431A01Rik, DYT6, FLJ10477 ENSG00000131931 THAP domain containing, apoptosis associated protein 1 8 42836674-42843325 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA071310 Supported Nucleus Mixed testis: 17.6 -RHPN2 ENSG00000131941 Rhophilin, Rho GTPase binding protein 2 19 32978593-33064888 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051749 Uncertain Mixed prostate: 41.9 -C19orf12 DKFZP762D096, MGC10922, NBIA4, SPG43 ENSG00000131943 Chromosome 19 open reading frame 12 19 29698886-29715789 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046930 Approved Expressed in all adipose tissue: 122.4 -FAAP24 C19orf40, FLJ46828, MGC32020 ENSG00000131944 Fanconi anemia core complex associated protein 24 19 32972209-32978222 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041168 Uncertain Supported Nucleoplasm
Vesicles Mixed testis: 12.3 -LRRC9 FLJ46156 ENSG00000131951 Leucine rich repeat containing 9 14 59919713-60063559 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040965, HPA041381 Uncertain Tissue enhanced 0 parathyroid gland: 3.4;testis: 10.8 fallopian tube: 1.9 -ACTR10 ACTR11, Arp10, Arp11, HARP11 ENSG00000131966 Actin-related protein 10 homolog (S. cerevisiae) 14 58200080-58235636 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071251 Approved Nucleoli Mixed adipose tissue: 11.7 -ABHD12B BEM46L3, C14orf29 ENSG00000131969 Abhydrolase domain containing 12B 14 50872160-50904970 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA002873 Uncertain Uncertain Nucleus Tissue enriched 6 skin: 16.3 breast: 2.5 -GCH1 DYT14, DYT5, DYT5a, GCH, GTPCH1 ENSG00000131979 GTP cyclohydrolase 1 14 54842008-54902852 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028612 Approved Supported Nucleoplasm
Nuclear membrane
Cytosol Tissue enhanced 0 bone marrow: 22.7 liver: 18.8 -LGALS3 GALIG, LGALS2, MAC-2 ENSG00000131981 Lectin, galactoside-binding, soluble, 3 14 55124110-55145413 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003162, CAB005191 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all colon: 886.8 -PODNL1 FLJ23447, SLRR5B ENSG00000132000 Podocan-like 1 19 13931187-13953392 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042807 Approved Tissue enhanced 0 placenta: 12.3 skin: 8.5 -DNAJB1 Hsp40, HSPF1, RSPH16B, Sis1 ENSG00000132002 DnaJ (Hsp40) homolog, subfamily B, member 1 19 14514770-14529770 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017450, HPA063247 Supported Validated Nucleus
Cytosol Expressed in all adrenal gland: 351.6 -ZSWIM4 FLJ12221 ENSG00000132003 Zinc finger, SWIM-type containing 4 19 13795460-13832230 Plasma proteins, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042084 Uncertain Mixed appendix: 5.9 -FBXW9 Fbw9, MGC10870 ENSG00000132004 F-box and WD repeat domain containing 9 19 12688053-12696643 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042087 Approved Approved Cytosol Mixed fallopian tube: 20.7 -RFX1 EF-C ENSG00000132005 Regulatory factor X, 1 (influences HLA class II expression) 19 13961538-14007039 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048722 Approved Supported Nucleoplasm Expressed in all testis: 16.8 -ZNF20 KOX13 ENSG00000132010 Zinc finger protein 20 19 12092843-12140407 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020887 Uncertain Approved Nucleoplasm
Plasma membrane Mixed testis: 9.3 -C19orf57 MGC11271 ENSG00000132016 Chromosome 19 open reading frame 57 19 13882348-13906452 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044012, HPA054615 Approved Approved Nucleoplasm Tissue enhanced 0 testis: 20.7 skin: 13.9 -DCAF15 C19orf72, MGC99481 ENSG00000132017 DDB1 and CUL4 associated factor 15 19 13952492-13961449 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA068351 Approved Vesicles
Mitochondria Expressed in all testis: 59.9 -CC2D1A FLJ20241, MRT3 ENSG00000132024 Coiled-coil and C2 domain containing 1A 19 13906201-13930879 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005436, CAB015220 Supported Supported Nucleoli fibrillar center
Plasma membrane
Cytosol Expressed in all duodenum: 36.6 -RTBDN FLJ36353 ENSG00000132026 Retbindin 19 12825478-12835428 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052511 Approved Endoplasmic reticulum Group enriched 6 adrenal gland: 4.6;cerebral cortex: 14.7;testis: 3.5 stomach: 1.2 -MATN3 EDM5, HOA ENSG00000132031 Matrilin 3 2 19992111-20012694 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051250 Approved Endoplasmic reticulum
Golgi apparatus Tissue enhanced 0 lung: 20.2;placenta: 16.4 seminal vesicle: 6.2 -TRIM21 RNF81, Ro/SSA, RO52, SSA1 ENSG00000132109 Tripartite motif containing 21 11 4384897-4393696 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004566, HPA005673 Approved Approved Nucleoplasm Expressed in all spleen: 41.8 -SPATA6 FLJ10007, SRF-1, SRF1 ENSG00000132122 Spermatogenesis associated 6 1 48295372-48472208 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028234 Approved Nucleoplasm
Golgi apparatus
Vesicles Tissue enhanced 0 testis: 88.4 fallopian tube: 24.3 -LRRC41 MUF1 ENSG00000132128 Leucine rich repeat containing 41 1 46261196-46303608 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051941 Uncertain Approved Nucleoplasm
Nuclear bodies Expressed in all fallopian tube: 68.8 -CCT6B Cctz2, TSA303 ENSG00000132141 Chaperonin containing TCP1, subunit 6B (zeta 2) 17 34927859-34981078 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042996, HPA045576, HPA049949 Uncertain Approved Cytosol Tissue enriched 33 testis: 223.4 breast: 6.8 -DHX30 DDX30, FLJ11214, KIAA0890 ENSG00000132153 DEAH (Asp-Glu-Ala-His) box helicase 30 3 47802909-47850195 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034806 Supported Supported Mitochondria
Cytosol Expressed in all testis: 46.7 -RAF1 c-Raf, CRAF, Raf-1 ENSG00000132155 Raf-1 proto-oncogene, serine/threonine kinase 3 12583601-12664226 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002640, CAB019291 Approved Approved Nuclear speckles Expressed in all parathyroid gland: 100.1 -SLC6A11 GAT3 ENSG00000132164 Solute carrier family 6 (neurotransmitter transporter), member 11 3 10816200-10940733 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037981 Supported Supported Tissue enhanced 0 cerebral cortex: 18.2;skin: 6.7 esophagus: 5.5 -PPARG NR1C3, PPARG1, PPARG2, PPARgamma ENSG00000132170 Peroxisome proliferator-activated receptor gamma 3 12287368-12434356 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004282, HPA051239, HPA063663 Approved Validated Nucleus
Vesicles Tissue enhanced 0 adipose tissue: 172.8 placenta: 58.6 -NUP210 FLJ22389, GP210, KIAA0906, POM210 ENSG00000132182 Nucleoporin 210kDa 3 13316235-13420309 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA066888 Approved Expressed in all lymph node: 49.2 -FCRLA FCRL, FCRLa, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRLM1, FCRLX, FREB, MGC4595 ENSG00000132185 Fc receptor-like A 1 161706972-161714352 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016545 Supported Group enriched 10 appendix: 32.5;lymph node: 81.6;spleen: 57.4;tonsil: 90.1 urinary bladder: 6.5 -HSD17B7 PRAP, SDR37C1 ENSG00000132196 Hydroxysteroid (17-beta) dehydrogenase 7 1 162790702-162812817 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047496 Approved Mixed liver: 17.2 -ENOSF1 HSRTSBETA, rTS, TYMSAS ENSG00000132199 Enolase superfamily member 1 18 670324-712676 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047829 Supported Mixed kidney: 38.7 -EMILIN2 FLJ33200, FOAP-10 ENSG00000132205 Elastin microfibril interfacer 2 18 2847030-2915993 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040739 Uncertain Tissue enriched 8 parathyroid gland: 264.7 placenta: 31.2 -SLX1A GIYD1 ENSG00000132207 SLX1 homolog A, structure-specific endonuclease subunit 16 30193887-30197561 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047038 Uncertain Approved Nucleoplasm Expressed in all duodenum: 51.8 -ARFIP2 POR1 ENSG00000132254 ADP-ribosylation factor interacting protein 2 11 6474683-6481479 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB032985, HPA038156 Approved Approved Nucleus
Nucleoli fibrillar center
Golgi apparatus Expressed in all parathyroid gland: 81.1 -TRIM5 RNF88, TRIM5alpha ENSG00000132256 Tripartite motif containing 5 11 5663557-5938619 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013497, HPA023420, HPA023422 Approved Supported Cytosol Mixed breast: 39.9 -CNGA4 CNCA2, CNG5, CNGB2, OCNC2, OCNCb ENSG00000132259 Cyclic nucleotide gated channel alpha 4 11 6234765-6244429 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 9 fallopian tube: 27.6;testis: 10.5 lung: 2.1 -TRIM22 GPSTAF50, RNF94, STAF50 ENSG00000132274 Tripartite motif containing 22 11 5689689-5737089 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003307, HPA003575 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all spleen: 181.2 -RRP8 KIAA0409 ENSG00000132275 Ribosomal RNA processing 8, methyltransferase, homolog (yeast) 11 6595075-6603620 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038487, HPA057562 Supported Supported Nucleus
Nucleoli
Cytosol Expressed in all seminal vesicle: 12.2 -TIMM10B FXC1, TIM10B, Tim9b ENSG00000132286 Translocase of inner mitochondrial membrane 10 homolog B (yeast) 11 6481447-6484679 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052265 Approved Expressed in all parathyroid gland: 52.0 -EFR3A KIAA0143 ENSG00000132294 EFR3 homolog A 8 131904088-132013642 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022859, HPA023092, HPA023402 Supported Supported Plasma membrane
Cytosol Expressed in all cerebral cortex: 67.5 -HHLA1 PLA2L ENSG00000132297 HERV-H LTR-associating 1 8 132061486-132111159 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected placenta: 0.1 -PTCD3 DKFZp666K071, FLJ20758 ENSG00000132300 Pentatricopeptide repeat domain 3 2 86106182-86142157 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041154, HPA041382 Supported Validated Mitochondria Expressed in all testis: 31.2 -IMMT HMP, Mic60, MINOS2, P87, P89 ENSG00000132305 Inner membrane protein, mitochondrial 2 86143932-86195770 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022439, HPA036164, HPA036165 Supported Validated Mitochondria Expressed in all parathyroid gland: 106.1 -MRPL35 ENSG00000132313 Mitochondrial ribosomal protein L35 2 86199355-86213794 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043482 Uncertain Expressed in all rectum: 65.6 -IQCA1 DRC11, FLJ22527, IQCA ENSG00000132321 IQ motif containing with AAA domain 1 2 236324147-236507542 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057320 Uncertain Nucleus Tissue enhanced 0 fallopian tube: 17.7;thyroid gland: 32.1 cerebral cortex: 11.5 -ILKAP DKFZP434J2031, FLJ10181 ENSG00000132323 Integrin-linked kinase-associated serine/threonine phosphatase 2 238170401-238203729 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004752, HPA056099 Uncertain Approved Nucleoplasm Expressed in all testis: 28.0 -PER2 KIAA0347 ENSG00000132326 Period circadian clock 2 2 238244038-238290102 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060510 Supported Expressed in all testis: 22.5 -RAMP1 ENSG00000132329 Receptor (G protein-coupled) activity modifying protein 1 2 237858893-237912114 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057814 Approved Nucleoplasm
Nuclear membrane Tissue enhanced 0 endometrium: 233.7 smooth muscle: 169.4 -SCLY SCL ENSG00000132330 Selenocysteine lyase 2 238060889-238099413 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055760 Uncertain Approved Golgi apparatus Expressed in all testis: 12.8 -PTPRE PTPE ENSG00000132334 Protein tyrosine phosphatase, receptor type, E 10 127907061-128085855 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015870, HPA021872 Supported Approved Intermediate filaments Mixed appendix: 35.7 -RAN ARA24, Gsp1, TC4 ENSG00000132341 RAN, member RAS oncogene family 12 130871879-130877678 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063353 Uncertain Nucleus Expressed in all testis: 557.0 -PRKAA1 AMPKa1 ENSG00000132356 Protein kinase, AMP-activated, alpha 1 catalytic subunit 5 40759379-40798374 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005050, HPA035409, HPA064946 Supported Supported Nuclear speckles Expressed in all testis: 74.4 -CARD6 CINCIN1 ENSG00000132357 Caspase recruitment domain family, member 6 5 40841184-40860175 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036438 Uncertain Approved Focal adhesion sites
Cytosol Mixed spleen: 17.2 -RAP1GAP2 GARNL4, KIAA1039 ENSG00000132359 RAP1 GTPase activating protein 2 17 2777056-3037739 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022148, HPA022896 Approved Supported Nuclear membrane
Cytosol Mixed cerebral cortex: 35.1 -CLUH CLU1, KIAA0664 ENSG00000132361 Clustered mitochondria (cluA/CLU1) homolog 17 2689386-2712663 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031505, HPA044346 Uncertain Supported Nuclear bodies
Vesicles Expressed in all esophagus: 50.9 -INPP5K SKIP ENSG00000132376 Inositol polyphosphate-5-phosphatase K 17 1494571-1516888 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031044 Uncertain Expressed in all adipose tissue: 32.1 -MYBBP1A FLJ37886, P160, PAP2 ENSG00000132382 MYB binding protein (P160) 1a 17 4538897-4555631 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005466 Supported Supported Nucleoli
Vesicles Expressed in all skin: 21.7 -RPA1 HSSB, REPA1, RF-A, RP-A, RPA70 ENSG00000132383 Replication protein A1, 70kDa 17 1829702-1900082 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004563, HPA006914, HPA046497 Supported Validated Nucleoplasm Expressed in all fallopian tube: 44.3 -SERPINF1 EPC-1, PEDF, PIG35 ENSG00000132386 Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 17 1761959-1777574 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005825 Approved Expressed in all gallbladder: 742.8 -UBE2G1 UBC7, UBE2G ENSG00000132388 Ubiquitin-conjugating enzyme E2G 1 17 4269259-4366628 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045681, HPA050551 Approved Approved Nucleoplasm
Cytosol Expressed in all skeletal muscle: 73.2 -EEFSEC EFSEC, SELB ENSG00000132394 Eukaryotic elongation factor, selenocysteine-tRNA-specific 3 128153454-128408646 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035795 Approved Approved Nucleus
Nuclear bodies
Cytosol Expressed in all testis: 18.8 -TBC1D14 KIAA1322 ENSG00000132405 TBC1 domain family, member 14 4 6909242-7033118 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036930, HPA067398 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Expressed in all cerebral cortex: 67.7 -TMEM128 MGC13159 ENSG00000132406 Transmembrane protein 128 4 4235542-4248212 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044809 Uncertain Expressed in all thyroid gland: 63.7 -COQ3 bA9819.1 ENSG00000132423 Coenzyme Q3 methyltransferase 6 99369400-99394204 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031273, HPA031274 Supported Approved Nucleoplasm
Mitochondria Expressed in all parathyroid gland: 20.6 -PNISR bA98I9.2, C6orf111, DKFZp564B0769, FLJ14752, SFRS18, SRrp130 ENSG00000132424 PNN-interacting serine/arginine-rich protein 6 99398051-99425331 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038796 Uncertain Supported Nuclear speckles
Cytosol Expressed in all endometrium: 126.6 -POPDC3 bA355M14.1, MGC22671, POP3 ENSG00000132429 Popeye domain containing 3 6 105158280-105179995 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA012514 Uncertain Approved Nucleoli
Cytosol Group enriched 6 cerebral cortex: 8.8;heart muscle: 18.4;skeletal muscle: 41.8;testis: 9.7 epididymis: 3.4 -SEC61G SSS1 ENSG00000132432 Sec61 translocon gamma subunit 7 54752250-54759974 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053196 Uncertain Expressed in all epididymis: 401.2 -LANCL2 GPR69B, TASP ENSG00000132434 LanC lantibiotic synthetase component C-like 2 (bacterial) 7 55365448-55433742 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019711, HPA029535 Uncertain Supported Nucleus
Cytosol Tissue enhanced 0 cerebral cortex: 41.3 parathyroid gland: 16.4 -FIGNL1 ENSG00000132436 Fidgetin-like 1 7 50444128-50542535 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055542 Approved Mixed smooth muscle: 14.5 -DDC AADC ENSG00000132437 Dopa decarboxylase (aromatic L-amino acid decarboxylase) 7 50458436-50565457 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017742 Supported Approved Actin filaments Tissue enhanced 0 duodenum: 159.5;kidney: 318.7;small intestine: 184.3 adrenal gland: 64.1 -FTHL17 CT38 ENSG00000132446 Ferritin, heavy polypeptide-like 17 X 31071241-31072053 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 14 testis: 3.5 skin: 0.2 -GRSF1 ENSG00000132463 G-rich RNA sequence binding factor 1 4 70815782-70839945 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036984, HPA036985 Supported Validated Mitochondria Expressed in all skeletal muscle: 95.8 -ENAM AIH2 ENSG00000132464 Enamelin 4 70628744-70686816 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 epididymis: 8.1;kidney: 5.8 heart muscle: 2.6 -JCHAIN IGCJ, IGJ, JCH ENSG00000132465 Joining chain of multimeric IgA and IgM 4 70655541-70681817 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034436, HPA044132 Supported Expressed in all colon: 7111.0 -ANKRD17 FLJ22206, GTAR, KIAA0697, MASK2, NY-BR-16 ENSG00000132466 Ankyrin repeat domain 17 4 73073376-73258798 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045024, HPA063731 Approved Supported Nucleus
Nuclear membrane Expressed in all parathyroid gland: 48.8 -UTP3 CRLZ1, DKFZp761F222, FLJ23256, SAS10 ENSG00000132467 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 4 70688479-70690551 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035655, HPA041453 Approved Approved Nucleoli Expressed in all spleen: 43.9 -ITGB4 CD104 ENSG00000132470 Integrin, beta 4 17 75721328-75757818 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002422, CAB005258, HPA036348, HPA036349 Supported Supported Nucleus
Plasma membrane
Cell Junctions Mixed skin: 84.4 -WBP2 WBP-2 ENSG00000132471 WW domain binding protein 2 17 75845699-75856507 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065682, HPA068819 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 361.8 -H3F3B H3.3B ENSG00000132475 H3 histone, family 3B (H3.3B) 17 75776434-75785893 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB037166, CAB037187, CAB037221, HPA042570 Supported Validated Nucleoplasm Expressed in all bone marrow: 2838.4 -UNK KIAA1753, ZC3H5, ZC3HDC5 ENSG00000132478 Unkempt family zinc finger 17 75784771-75825799 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023636, HPA027962 Uncertain Supported Cytosol
Cytoplasmic bodies Expressed in all skin: 16.5 -TRIM47 GOA, RNF100 ENSG00000132481 Tripartite motif containing 47 17 75874161-75878575 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014933 Uncertain Supported Cytosol Mixed cerebral cortex: 23.9 -ZRANB2 ZIS, ZIS1, ZIS2, ZNF265 ENSG00000132485 Zinc finger, RAN-binding domain containing 2 1 71063291-71081297 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053960, HPA061949, HPA063298 Supported Validated Nucleus Expressed in all endometrium: 117.1 -EIF5A EIF-5A, EIF5A1, MGC104255, MGC99547 ENSG00000132507 Eukaryotic translation initiation factor 5A 17 7306999-7312463 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005042, HPA061298 Approved Validated Nucleoplasm
Cytosol Expressed in all esophagus: 437.6 -KDM6B JMJD3, KIAA0346 ENSG00000132510 Lysine (K)-specific demethylase 6B 17 7839904-7854796 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037988 Supported Approved Nuclear speckles Expressed in all appendix: 29.5 -CLEC10A CD301, CLECSF13, CLECSF14, HML, HML2 ENSG00000132514 C-type lectin domain family 10, member A 17 7074537-7080307 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA021937 Approved Mixed appendix: 40.3 -SLC52A1 FLJ10060, GPCR42, GPR172B, hRFT1, PAR2, RFVT1 ENSG00000132517 Solute carrier family 52 (riboflavin transporter), member 1 17 5032600-5052009 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level CAB011449 Uncertain Group enriched 10 duodenum: 37.1;placenta: 26.0;skin: 13.3;small intestine: 26.8 parathyroid gland: 2.6 -GUCY2D CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, retGC, RETGC-1, ROS-GC1 ENSG00000132518 Guanylate cyclase 2D, membrane (retina-specific) 17 8002594-8020339 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 testis: 1.4 lymph node: 0.3 -GPS2 ENSG00000132522 G protein pathway suppressor 2 17 7311324-7315564 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067540 Supported Nucleoplasm Expressed in all testis: 97.2 -XAF1 BIRC4BP, HSXIAPAF1, XIAPAF1 ENSG00000132530 XIAP associated factor 1 17 6755447-6775647 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057302 Approved Supported Nucleus
Mitochondria
Rods & Rings Mixed spleen: 83.0 -DLG4 PSD-95, PSD95, SAP-90, SAP90 ENSG00000132535 Discs, large homolog 4 (Drosophila) 17 7189890-7219702 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001999, CAB002000, HPA010122 Supported Approved Vesicles Tissue enriched 6 cerebral cortex: 179.1 endometrium: 28.9 -HRSP12 P14.5, PSP, UK114 ENSG00000132541 Heat-responsive protein 12 8 98102344-98117241 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022856, HPA023489 Supported Group enriched 9 kidney: 451.5;liver: 696.6 cerebral cortex: 62.5 -VPS13B CHS1, COH1 ENSG00000132549 Vacuolar protein sorting 13 homolog B (yeast) 8 99013266-99877580 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043865 Approved Cell Junctions Mixed parathyroid gland: 14.4 -RGS22 CT145, DKFZP434I092, PRTD-NY2 ENSG00000132554 Regulator of G-protein signaling 22 8 99960936-100131268 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 testis: 108.4 fallopian tube: 16.5 -MATN2 ENSG00000132561 Matrilin 2 8 97868840-98036716 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033879 Approved Expressed in all thyroid gland: 454.2 -REEP2 C5orf19, SGC32445, SPG72 ENSG00000132563 Receptor accessory protein 2 5 138439017-138446969 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031813 Supported Tissue enriched 5 cerebral cortex: 90.3 smooth muscle: 17.8 -PCBD2 DCOH2, DCOHM ENSG00000132570 Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 5 134904906-135007959 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036428 Uncertain Approved Plasma membrane Expressed in all parathyroid gland: 16.0 -SDF2 ENSG00000132581 Stromal cell-derived factor 2 17 28648356-28662189 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042799 Approved Vesicles Expressed in all adrenal gland: 27.9 -FLOT2 ECS-1, ECS1, ESA, ESA1, M17S1 ENSG00000132589 Flotillin 2 17 28879335-28897679 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001396, CAB004395 Supported Expressed in all spleen: 95.3 -ERAL1 HERA-B ENSG00000132591 Era-like 12S mitochondrial rRNA chaperone 1 17 28854938-28861067 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021425, HPA024423 Supported Validated Mitochondria
Cytosol Expressed in all parathyroid gland: 50.2 -PRMT7 FLJ10640, KIAA1933 ENSG00000132600 Protein arginine methyltransferase 7 16 68310974-68358563 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044241 Supported Supported Nucleoplasm
Nucleoli fibrillar center Expressed in all fallopian tube: 24.8 -NIP7 CGI-37, FLJ10296, HSPC031, KD93 ENSG00000132603 NIP7, nucleolar pre-rRNA processing protein 16 69339430-69343111 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040856, HPA059850 Supported Supported Nucleus
Nucleoli Expressed in all lymph node: 23.3 -TERF2 TRBF2, TRF2 ENSG00000132604 Telomeric repeat binding factor 2 16 69355561-69408571 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001907, HPA002735, CAB010451 Supported Supported Nuclear bodies Expressed in all lymph node: 42.7 -VPS4A FLJ22197, SKD1, SKD1A, SKD2, VPS4, VPS4-1 ENSG00000132612 Vacuolar protein sorting 4 homolog A (S. cerevisiae) 16 69311356-69326939 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018751, CAB034411, HPA060092 Approved Supported Midbody Expressed in all parathyroid gland: 46.8 -MTSS1L ABBA-1, LOC92154 ENSG00000132613 Metastasis suppressor 1-like 16 70661204-70686066 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048531, HPA066469 Approved Supported Focal adhesion sites Expressed in all cerebral cortex: 320.9 -HSPA12B C20orf60, dJ1009E24.2 ENSG00000132622 Heat shock 70kD protein 12B 20 3732667-3753111 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013659, HPA015639 Uncertain Mixed spleen: 25.9 -ANKEF1 ANKRD5, dJ839B4.6, FLJ21669 ENSG00000132623 Ankyrin repeat and EF-hand domain containing 1 20 9986126-10058303 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041151 Approved Approved Nucleoli fibrillar center
Plasma membrane
Cytosol Tissue enhanced 0 testis: 33.7 thyroid gland: 11.3 -SCP2D1 C20orf79, dJ1068E13.2, HSD22 ENSG00000132631 SCP2 sterol-binding domain containing 1 20 18813726-18814392 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 588 testis: 58.7 adipose tissue: 0.0 -PCED1A bA12M19.1, C20orf81, FAM113A, FLJ22376 ENSG00000132635 PC-esterase domain containing 1A 20 2835314-2841190 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA050816 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 79.9 -SNAP25 bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25 ENSG00000132639 Synaptosomal-associated protein, 25kDa 20 10218830-10307418 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000360, HPA001830 Supported Supported Tissue enriched 31 cerebral cortex: 1764.2 adrenal gland: 57.4 -BTBD3 dJ742J24.1, KIAA0952 ENSG00000132640 BTB (POZ) domain containing 3 20 11890723-11926609 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041424, HPA042048 Uncertain Supported Vesicles Expressed in all placenta: 59.7 -PCNA ENSG00000132646 Proliferating cell nuclear antigen 20 5114953-5126626 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000148, HPA030521, HPA030522, HPA030523 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all bone marrow: 223.6 -NXT1 MTR2, P15 ENSG00000132661 Nuclear transport factor 2-like export factor 1 20 23350736-23354777 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047471 Supported Nucleoplasm
Cytosol Expressed in all bone marrow: 26.7 -POLR3F RPC39, RPC6 ENSG00000132664 Polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 20 18467127-18484643 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049441, HPA050173, HPA072298 Uncertain Approved Nucleus Mixed thyroid gland: 11.6 -RIN2 RASSF4 ENSG00000132669 Ras and Rab interactor 2 20 19886521-20002457 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034641 Approved Approved Nucleoli
Golgi apparatus
Cytosol Expressed in all gallbladder: 29.0 -PTPRA HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA ENSG00000132670 Protein tyrosine phosphatase, receptor type, A 20 2864184-3039076 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029412, CAB034366, HPA069480 Approved Approved Nucleus
Vesicles Expressed in all cerebral cortex: 167.8 -SSTR4 ENSG00000132671 Somatostatin receptor 4 20 23035386-23036812 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA064252 Uncertain Not detected cerebral cortex: 0.8 -DAP3 bMRP-10, DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29 ENSG00000132676 Death associated protein 3 1 155687960-155739010 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023687 Approved Supported Nucleoplasm
Mitochondria Expressed in all prostate: 84.1 -RHBG SLC42A2 ENSG00000132677 Rh family, B glycoprotein (gene/pseudogene) 1 156369212-156385219 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA042726, HPA048489 Approved Approved Nucleoplasm Tissue enhanced 0 kidney: 3.5;ovary: 2.0 liver: 0.6 -KIAA0907 BLOM7 ENSG00000132680 KIAA0907 1 155913043-155934400 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008796 Approved Approved Nucleoplasm Expressed in all epididymis: 54.4 -ATP1A4 ATP1AL2 ENSG00000132681 ATPase, Na+/K+ transporting, alpha 4 polypeptide 1 160151570-160186977 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 placenta: 10.1;testis: 18.1;urinary bladder: 8.9 lymph node: 4.1 -NES FLJ21841 ENSG00000132688 Nestin 1 156668763-156677397 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005889, HPA006286, HPA007007, HPA026111, CAB058692 Supported Validated Intermediate filaments Tissue enhanced 0 heart muscle: 107.4 spleen: 57.9 -BCAN BEHAB, CSPG7, MGC13038 ENSG00000132692 Brevican 1 156641390-156659532 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007865, CAB025862 Supported Tissue enriched 24 cerebral cortex: 429.4 epididymis: 17.9 -CRP PTX1 ENSG00000132693 C-reactive protein, pentraxin-related 1 159712289-159714589 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005036, HPA027367, HPA027396 Supported Group enriched 68 gallbladder: 173.7;liver: 532.4 endometrium: 5.2 -ARHGEF11 GTRAP48, KIAA0380, PDZ-RHOGEF ENSG00000132694 Rho guanine nucleotide exchange factor (GEF) 11 1 156934840-157045370 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011026, HPA012037, HPA014658 Approved Approved Golgi apparatus
Plasma membrane Expressed in all parathyroid gland: 43.6 -RAB25 CATX-8 ENSG00000132698 RAB25, member RAS oncogene family 1 156061160-156070514 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010872, CAB033645 Approved Uncertain Cell Junctions
Cytosol Tissue enhanced 0 esophagus: 298.6 skin: 169.3 -HAPLN2 BRAL1 ENSG00000132702 Hyaluronan and proteoglycan link protein 2 1 156619294-156625725 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045765 Supported Tissue enriched 46 cerebral cortex: 42.2 duodenum: 0.9 -APCS MGC88159, PTX2, SAP ENSG00000132703 Amyloid P component, serum 1 159587825-159588865 Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007817, HPA053294 Supported Tissue enriched 25 liver: 1844.2 gallbladder: 73.9 -FCRL2 CD307b, FCRH2, IRTA4, SPAP1 ENSG00000132704 Fc receptor-like 2 1 157745733-157777132 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 8 appendix: 16.9;lymph node: 28.7;spleen: 26.3;tonsil: 24.6 rectum: 3.1 -DCAF8 FLJ35857, H326, WDR42A ENSG00000132716 DDB1 and CUL4 associated factor 8 1 160215715-160262531 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027218, HPA027381 Supported Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 153.1 -SYT11 DKFZp781D015, KIAA0080, MGC10881, MGC17226 ENSG00000132718 Synaptotagmin XI 1 155859509-155885199 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064091 Supported Tissue enriched 14 cerebral cortex: 403.4 endometrium: 28.3 -IGHMBP2 CATF1, CMT2S, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7 ENSG00000132740 Immunoglobulin mu binding protein 2 11 68903842-68940602 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060994 Approved Nucleus Expressed in all testis: 28.0 -ACY3 ACY-3, HCBP1, MGC9740 ENSG00000132744 Aminoacylase 3 11 67642555-67650659 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039219, HPA048187 Supported Tissue enhanced 0 duodenum: 82.8;kidney: 53.1;small intestine: 80.3 cervix: 16.0 -ALDH3B2 ALDH8 ENSG00000132746 Aldehyde dehydrogenase 3 family, member B2 11 67662162-67681200 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045132 Approved Group enriched 5 breast: 88.2;esophagus: 103.8;skin: 122.4 tonsil: 19.7 -MTL5 CXCDC2 ENSG00000132749 Metallothionein-like 5, testis-specific (tesmin) 11 68707440-68751564 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA018539 Supported Nucleoplasm Tissue enriched 17 testis: 94.9 breast: 5.4 -MMACHC cblC, DKFZP564I122 ENSG00000132763 Methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 1 45500053-45513382 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027394, HPA027399, HPA027402 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Mixed liver: 8.9 -DPH2 DPH2L2 ENSG00000132768 DPH2 homolog 1 43970000-43973369 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045796 Uncertain Approved Nucleus Expressed in all appendix: 14.7 -TOE1 hCaf1z ENSG00000132773 Target of EGR1, member 1 (nuclear) 1 45339670-45343975 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053775, HPA069119 Supported Validated Nucleoplasm
Nuclear bodies Mixed testis: 11.8 -NASP DKFZp547F162, FLB7527, FLJ31599, FLJ35510, MGC19722, MGC20372, MGC2297, PRO1999 ENSG00000132780 Nuclear autoantigenic sperm protein (histone-binding) 1 45583846-45618904 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028136, HPA030518, HPA030520 Supported Validated Nucleoplasm Expressed in all testis: 149.9 -MUTYH MYH ENSG00000132781 MutY DNA glycosylase 1 45329163-45340470 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008732 Uncertain Supported Nucleus Mixed thyroid gland: 10.7 -CTNNBL1 C20orf33, FLJ21108, NAP, NYD-SP19, P14, P14L ENSG00000132792 Catenin, beta like 1 20 37693955-37872129 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004742, HPA027907 Approved Validated Nucleoplasm Expressed in all testis: 75.0 -LPIN3 LIPN3L, SMP2 ENSG00000132793 Lipin 3 20 41340920-41360582 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051466, HPA052667, HPA070640 Approved Supported Cytosol Mixed skin: 48.6 -ZSWIM3 C20orf164, dJ337O18.7, PPP1R174 ENSG00000132801 Zinc finger, SWIM-type containing 3 20 45857617-45879122 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055692, HPA060508 Uncertain Approved Nucleoli fibrillar center
Vesicles
Cytosol Mixed testis: 5.2 -RBM38 dJ800J21.2, HSRNASEB, RNPC1, seb4B, SEB4D ENSG00000132819 RNA binding motif protein 38 20 57391407-57409333 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017036 Approved Supported Nucleoplasm
Cytosol Expressed in all bone marrow: 86.9 -VSTM2L C20orf102, dJ1118M15.2 ENSG00000132821 V-set and transmembrane domain containing 2 like 20 37903104-37945350 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043832 Uncertain Tissue enhanced 0 cerebral cortex: 55.2 gallbladder: 26.9 -OSER1 C20orf111, dJ1183I21.1, HSPC207, Osr1, Perit1 ENSG00000132823 Oxidative stress responsive serine-rich 1 20 44196496-44210791 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045125 Approved Approved Nucleoli
Nuclear speckles Expressed in all testis: 183.6 -SERINC3 AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1 ENSG00000132824 Serine incorporator 3 20 44496221-44522109 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048116 Uncertain Expressed in all testis: 200.8 -PPP1R3D PPP1R6 ENSG00000132825 Protein phosphatase 1, regulatory subunit 3D 20 59936668-59940297 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041146 Approved Approved Nucleoli
Vesicles
Mitochondria Mixed parathyroid gland: 10.9 -DMGDH ENSG00000132837 Dimethylglycine dehydrogenase 5 78997606-79236038 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036441, HPA036442, HPA077849 Supported Uncertain Mitochondria Group enriched 11 kidney: 177.8;liver: 146.1 epididymis: 14.7 -BHMT2 ENSG00000132840 Betaine--homocysteine S-methyltransferase 2 5 79069717-79089466 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044573 Supported Group enriched 6 kidney: 360.3;liver: 238.4 epididymis: 46.4 -AP3B1 ADTB3A, HPS2 ENSG00000132842 Adaptor-related protein complex 3, beta 1 subunit 5 78000525-78294755 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038737, HPA045458 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all epididymis: 64.4 -ZBED3 MGC15435 ENSG00000132846 Zinc finger, BED-type containing 3 5 77072072-77087323 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055995 Approved Approved Nucleoplasm
Plasma membrane Mixed thyroid gland: 18.7 -INADL Cipp, PATJ ENSG00000132849 InaD-like (Drosophila) 1 61742477-62178675 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066352, HPA066960, HPA069079 Approved Supported Cell Junctions
Microtubule organizing center
Cytosol Expressed in all parathyroid gland: 35.2 -KANK4 ANKRD38, KIAA0172 ENSG00000132854 KN motif and ankyrin repeat domains 4 1 62236979-62319414 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014030 Uncertain Uncertain Microtubules
Cytosol Tissue enhanced 0 parathyroid gland: 28.9;placenta: 16.3 adipose tissue: 11.8 -ANGPTL3 ANGPT5 ENSG00000132855 Angiopoietin-like 3 1 62597487-62606159 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038097 Approved Tissue enriched 6 liver: 356.2 kidney: 55.3 -SYT4 HsT1192, KIAA1342 ENSG00000132872 Synaptotagmin IV 18 43267878-43277650 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010574 Approved Supported Vesicles
Plasma membrane Tissue enhanced 0 adrenal gland: 20.5;cerebral cortex: 82.7 seminal vesicle: 11.1 -SLC14A2 HUT2, UT2 ENSG00000132874 Solute carrier family 14 (urea transporter), member 2 18 45212995-45683686 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 kidney: 4.0 adipose tissue: 1.7 -FBXO44 FBG3, FBX30, Fbx44, Fbxo6a, MGC14140 ENSG00000132879 F-box protein 44 1 11654375-11663327 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003363 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 98.3 -RSG1 C1orf89, MGC10731 ENSG00000132881 REM2 and RAB-like small GTPase 1 1 16231700-16237162 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028453, HPA041672 Approved Validated Nucleoplasm Mixed fallopian tube: 10.9 -CASP9 APAF-3, ICE-LAP6, MCH6, PPP1R56 ENSG00000132906 Caspase 9, apoptosis-related cysteine peptidase 1 15490832-15526534 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001473, CAB004348, HPA046488 Approved Approved Mitochondria Expressed in all adrenal gland: 37.3 -NMUR2 NMU2R ENSG00000132911 Neuromedin U receptor 2 5 152391532-152433368 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045836 Approved Tissue enhanced 0 stomach: 1.1;testis: 2.2 thyroid gland: 0.9 -DCTN4 ENSG00000132912 Dynactin 4 (p62) 5 150708440-150759109 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017532, HPA038026 Uncertain Approved Nucleus
Centrosome Expressed in all cerebral cortex: 67.5 -PDE6A PDEA, RP43 ENSG00000132915 Phosphodiesterase 6A, cGMP-specific, rod, alpha 5 149857955-149944793 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016970 Uncertain Tissue enriched 8 epididymis: 20.2 testis: 2.4 -ATP8A2 ATPIB, ML-1 ENSG00000132932 ATPase, aminophospholipid transporter, class I, type 8A, member 2 13 25372071-26025851 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039926, HPA040033 Approved Supported Nucleoplasm
Plasma membrane Group enriched 6 cerebral cortex: 26.5;testis: 10.6 adrenal gland: 2.9 -MTUS2 CAZIP, ICIS, KIAA0774, TIP150 ENSG00000132938 Microtubule associated tumor suppressor candidate 2 13 28820348-29505947 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031473, HPA031474, HPA031475 Approved Supported Microtubules
Cytokinetic bridge Tissue enhanced 0 heart muscle: 32.6;ovary: 9.5 cerebral cortex: 4.3 -ZMYM5 MYM, ZNF198L1, ZNF237 ENSG00000132950 Zinc finger, MYM-type 5 13 19823482-19863636 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA020879 Uncertain Expressed in all testis: 44.2 -USPL1 bA121O19.1, C13orf22, D13S106E ENSG00000132952 Ubiquitin specific peptidase like 1 13 30617693-30660770 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039342, HPA040172 Uncertain Expressed in all testis: 40.3 -XPO4 FLJ13046, KIAA1721 ENSG00000132953 Exportin 4 13 20777329-20903048 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053768 Supported Nucleoplasm
Cytosol Mixed skeletal muscle: 15.7 -TPTE2 TPIP ENSG00000132958 Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 13 19422877-19536762 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA068342 Approved Endoplasmic reticulum
Cytosol Tissue enriched 33 testis: 11.9 tonsil: 0.3 -POMP C13orf12, HSPC014, UMP1 ENSG00000132963 Proteasome maturation protein 13 28659104-28678925 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026995 Approved Supported Nuclear speckles Expressed in all placenta: 143.9 -CDK8 K35 ENSG00000132964 Cyclin-dependent kinase 8 13 26254104-26405238 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044721 Approved Nucleus Expressed in all testis: 17.6 -ALOX5AP FLAP ENSG00000132965 Arachidonate 5-lipoxygenase-activating protein 13 30713478-30764426 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026592 Supported Expressed in all bone marrow: 302.3 -WASF3 KIAA0900, SCAR3, WAVE3 ENSG00000132970 WAS protein family, member 3 13 26557703-26688948 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB037086 Approved Tissue enhanced 0 cerebral cortex: 86.7 thyroid gland: 28.0 -RNF17 FLJ11045, Mmip-2, SPATA23, TDRD4 ENSG00000132972 Ring finger protein 17 13 24764152-24879921 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039699, HPA040111 Approved Tissue enriched 19 testis: 43.8 placenta: 2.3 -GPR12 GPCR21, PPP1R84 ENSG00000132975 G protein-coupled receptor 12 13 26755200-26760785 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA050972 Uncertain Tissue enhanced 0 cerebral cortex: 8.0 breast: 1.7 -CHRM3 ENSG00000133019 Cholinergic receptor, muscarinic 3 1 239386565-239915452 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024106, HPA048036 Approved Supported Plasma membrane Tissue enhanced 0 cerebral cortex: 15.7 esophagus: 8.5 -MYH8 MyHC-peri, MyHC-pn ENSG00000133020 Myosin, heavy chain 8, skeletal muscle, perinatal 17 10390322-10421950 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001349, CAB016527 Supported Group enriched 6 esophagus: 16.9;skeletal muscle: 5.5 prostate: 1.7 -MYH10 NMMHCB ENSG00000133026 Myosin, heavy chain 10, non-muscle 17 8474205-8630761 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017180, HPA047541, HPA057198 Supported Validated Actin filaments
Mitochondria
Cytosol Expressed in all lung: 81.2 -PEMT PEMPT, PEMT2 ENSG00000133027 Phosphatidylethanolamine N-methyltransferase 17 17505563-17591708 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042375 Approved Approved Cytosol Expressed in all epididymis: 205.4 -SCO1 SCOD1 ENSG00000133028 SCO1 cytochrome c oxidase assembly protein 17 10672474-10698375 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021565, HPA021579 Approved Expressed in all thyroid gland: 22.5 -MPRIP M-RIP, p116Rip, RHOIP3 ENSG00000133030 Myosin phosphatase Rho interacting protein 17 17042545-17217679 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022034, HPA022901 Supported Supported Actin filaments
Cytosol Expressed in all smooth muscle: 188.5 -CHI3L1 GP39, YKL40 ENSG00000133048 Chitinase 3-like 1 (cartilage glycoprotein-39) 1 203178931-203186749 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072269 Approved Vesicles Tissue enhanced 0 appendix: 191.3;cerebral cortex: 267.7;urinary bladder: 185.7 bone marrow: 147.1 -MYBPH ENSG00000133055 Myosin binding protein H 1 203167811-203175813 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061383 Approved Nucleus
Nucleoli
Mitochondria Tissue enhanced 0 prostate: 4.2;skeletal muscle: 7.9 esophagus: 1.2 -PIK3C2B C2-PI3K, PI3K-C2beta ENSG00000133056 Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 1 204422628-204494724 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030515, HPA050360 Approved Approved Nucleoplasm
Cytosol Mixed lymph node: 28.6 -DSTYK DustyPK, KIAA0472, RIP5, RIPK5 ENSG00000133059 Dual serine/threonine and tyrosine protein kinase 1 205142505-205211566 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044140 Uncertain Uncertain Nuclear speckles
Intermediate filaments Mixed parathyroid gland: 28.8 -CHIT1 CHI3, CHIT ENSG00000133063 Chitinase 1 (chitotriosidase) 1 203212827-203273641 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010575 Approved Group enriched 9 bone marrow: 31.3;breast: 10.7;cervix, uterine: 13.4;lung: 53.2;lymph node: 21.5 prostate: 2.9 -SLC41A1 MgtE ENSG00000133065 Solute carrier family 41 (magnesium transporter), member 1 1 205789093-205813748 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014721, HPA015138 Uncertain Approved Mitochondria Tissue enhanced 0 heart muscle: 72.6 testis: 37.3 -LGR6 FLJ14471 ENSG00000133067 Leucine-rich repeat containing G protein-coupled receptor 6 1 202193901-202319781 G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA008556 Approved Approved Nucleoplasm
Plasma membrane Tissue enhanced 0 fallopian tube: 14.1 gallbladder: 9.6 -TMCC2 FLJ38497, HUCEP11 ENSG00000133069 Transmembrane and coiled-coil domain family 2 1 205228176-205273343 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014254 Approved Tissue enhanced 0 bone marrow: 53.3;cerebral cortex: 25.0 placenta: 8.1 -DCLK1 DCAMKL1, DCDC3A, DCLK, KIAA0369 ENSG00000133083 Doublecortin-like kinase 1 13 35768652-36131306 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012405, HPA015040, HPA015655 Supported Approved Nucleus
Cytosol Tissue enriched 5 cerebral cortex: 140.9 smooth muscle: 27.0 -CCNA1 CT146 ENSG00000133101 Cyclin A1 13 36431520-36442882 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060646 Approved Nucleoplasm
Nuclear bodies Tissue enhanced 0 parathyroid gland: 58.7;testis: 143.7 fallopian tube: 27.6 -COG6 COD2, KIAA1134 ENSG00000133103 Component of oligomeric golgi complex 6 13 39655627-39791665 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040410, HPA040441 Uncertain Approved Nuclear speckles
Golgi apparatus Expressed in all testis: 31.6 -SPG20 KIAA0610, TAHCCP1 ENSG00000133104 Spastic paraplegia 20 (Troyer syndrome) 13 36301638-36370180 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039053, HPA039054, HPA061519 Approved Validated Plasma membrane
Cytosol Expressed in all epididymis: 80.0 -RXFP2 GPR106, GREAT, INSL3R, LGR8, RXFPR2 ENSG00000133105 Relaxin/insulin-like family peptide receptor 2 13 31739542-31803388 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected endometrium: 0.8 -EPSTI1 BRESI1, MGC29634 ENSG00000133106 Epithelial stromal interaction 1 (breast) 13 42886388-42992271 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA017362 Approved Approved Cytosol Mixed appendix: 44.1 -TRPC4 HTRP4, TRP4 ENSG00000133107 Transient receptor potential cation channel, subfamily C, member 4 13 37636636-37870425 Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 endometrium: 18.5;seminal vesicle: 12.0;smooth muscle: 18.2 prostate: 10.7 -POSTN OSF-2, periostin, PN ENSG00000133110 Periostin, osteoblast specific factor 13 37562583-37598844 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012306 Supported Approved Nucleoplasm
Golgi apparatus Mixed skin: 247.0 -RFXAP ENSG00000133111 Regulatory factor X-associated protein 13 36819224-36829104 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032035 Approved Nuclear speckles Mixed testis: 12.1 -TPT1 fortilin, TCTP ENSG00000133112 Tumor protein, translationally-controlled 1 13 45333471-45341370 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008364, HPA039437 Approved Supported Cytosol Expressed in all skeletal muscle: 8105.5 -GPALPP1 AD029, bA245H20.2, KIAA1704, LSR7 ENSG00000133114 GPALPP motifs containing 1 13 44989529-45037669 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038966, HPA058739 Uncertain Approved Nucleus
Nucleoli Expressed in all thyroid gland: 15.4 -STOML3 Epb7.2l, SRO ENSG00000133115 Stomatin (EPB72)-like 3 13 38965925-38991066 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012892, CAB014880 Approved Tissue enriched 17 fallopian tube: 49.7 lung: 2.8 -KL ENSG00000133116 Klotho 13 33016433-33066145 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 kidney: 135.6;parathyroid gland: 340.1 placenta: 43.7 -RFC3 MGC5276, RFC38 ENSG00000133119 Replication factor C (activator 1) 3, 38kDa 13 33818049-33966558 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030149 Approved Supported Nucleoplasm
Vesicles Mixed lymph node: 27.1 -STARD13 ARHGAP37, DLC2, GT650, LINC00464 ENSG00000133121 StAR-related lipid transfer (START) domain containing 13 13 33103135-33350630 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039535, HPA058867 Supported Approved Nuclear membrane
Nucleoli
Cytosol Mixed placenta: 35.0 -IRS4 IRS-4, PY160 ENSG00000133124 Insulin receptor substrate 4 X 108732482-108736409 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017372 Uncertain Tissue enhanced 0 endometrium: 1.7;ovary: 4.4;thyroid gland: 2.1 cervix: 1.1 -MORC4 FLJ11565, ZCW4, ZCWCC2 ENSG00000133131 MORC family CW-type zinc finger 4 X 106813871-107000244 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000395, HPA015547, HPA050250 Supported Validated Nucleoplasm Expressed in all placenta: 113.4 -BEX2 DJ79P11.1 ENSG00000133134 Brain expressed X-linked 2 X 103309346-103311046 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045384 Uncertain Tissue enhanced 0 cerebral cortex: 227.2 thyroid gland: 156.4 -RNF128 FLJ23516, GRAIL ENSG00000133135 Ring finger protein 128, E3 ubiquitin protein ligase X 106693794-106796993 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA019675 Uncertain Mixed small intestine: 68.3 -TBC1D8B FLJ20298, RP11-321G1.1 ENSG00000133138 TBC1 domain family, member 8B (with GRAM domain) X 106802680-106876145 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023883, HPA027527 Approved Supported Approved Cytosol Expressed in all adrenal gland: 26.6 -TCEAL4 FLJ21174, WEX7 ENSG00000133142 Transcription elongation factor A (SII)-like 4 X 103576231-103587736 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 557.2 -BEX1 ENSG00000133169 Brain expressed, X-linked 1 X 103062651-103064240 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045384 Approved Tissue enhanced 0 cerebral cortex: 506.7 parathyroid gland: 151.6 -FAM104A FLJ14775 ENSG00000133193 Family with sequence similarity 104, member A 17 73207353-73236753 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021459 Approved Nucleoplasm
Cytosol Tissue enriched 6 testis: 163.0 bone marrow: 27.1 -SLC39A11 C17orf26 ENSG00000133195 Solute carrier family 39, member 11 17 72645949-73092712 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021455 Approved Nucleoplasm Expressed in all thyroid gland: 60.0 -EPHB2 DRT, EPHT3, ERK, Hek5, Tyro5 ENSG00000133216 EPH receptor B2 1 22710839-22921500 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013647, HPA071200 Approved Supported Nucleus
Plasma membrane Mixed rectum: 27.8 -SRRM1 MGC39488, POP101, SRM160 ENSG00000133226 Serine/arginine repetitive matrix 1 1 24631716-24673267 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049941, HPA058612 Supported Validated Nuclear speckles Expressed in all epididymis: 96.3 -BTBD2 ENSG00000133243 BTB (POZ) domain containing 2 19 1985438-2034881 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 75.1 -PRAM1 PML-RAR ENSG00000133246 PML-RARA regulated adaptor molecule 1 19 8490056-8503112 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045236, HPA050161 Approved Approved Golgi apparatus Tissue enhanced 0 bone marrow: 65.2 appendix: 15.6 -SUV420H2 KMT5C, MGC2705 ENSG00000133247 Suppressor of variegation 4-20 homolog 2 (Drosophila) 19 55339853-55348120 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052294 Uncertain Approved Nucleoplasm Mixed skin: 4.8 -ZNF414 MGC15716, Zfp414 ENSG00000133250 Zinc finger protein 414 19 8509678-8514164 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053769 Approved Approved Nucleus
Cytosol Expressed in all spleen: 12.6 -PDE6B CSNB3, CSNBAD2, PDEB, rd1, RP40 ENSG00000133256 Phosphodiesterase 6B, cGMP-specific, rod, beta 4 625584-670782 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054148, HPA059929 Supported Approved Cytosol Mixed cerebral cortex: 22.4 -HSPBP1 FES1, HspBP1 ENSG00000133265 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 19 55262231-55280381 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005865, HPA071444 Supported Approved Vesicles
Cytosol Expressed in all fallopian tube: 39.6 -CSNK1G2 CK1g2 ENSG00000133275 Casein kinase 1, gamma 2 19 1941149-1981338 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034868, HPA056572 Uncertain Approved Vesicles Expressed in all testis: 77.2 -SLF1 ANKRD32, BRCTD1, BRCTx, DKFZp564C0469, DKFZp761C121 ENSG00000133302 SMC5-SMC6 complex localization factor 1 5 94618347-94739436 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040793, HPA054213 Uncertain Approved Nucleus Tissue enhanced 0 testis: 12.8 cerebral cortex: 4.4 -CNDP2 CN2, CPGL, FLJ10830, HsT2298, PEPA ENSG00000133313 CNDP dipeptidase 2 (metallopeptidase M20 family) 18 74495816-74523454 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026196, HPA036898, HPA036899 Supported Validated Nucleoplasm
Cytosol Expressed in all kidney: 341.1 -MACROD1 LRP16 ENSG00000133315 MACRO domain containing 1 11 63998558-64166106 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041031, HPA071075 Uncertain Supported Nucleoplasm Tissue enriched 6 skeletal muscle: 106.6 kidney: 17.4 -WDR74 FLJ10439 ENSG00000133316 WD repeat domain 74 11 62832342-62841809 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037795, HPA038419 Uncertain Supported Nucleus
Nucleoli Expressed in all bone marrow: 83.6 -LGALS12 GRIP1 ENSG00000133317 Lectin, galactoside-binding, soluble, 12 11 63506084-63516774 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 adipose tissue: 89.7 bone marrow: 12.6 -RTN3 ASYIP, HAP, NSPL2, NSPLII, RTN3-A1 ENSG00000133318 Reticulon 3 11 63681446-63759891 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015649, HPA015650 Supported Supported Endoplasmic reticulum Expressed in all cerebral cortex: 1033.6 -RARRES3 HRASLS4, TIG3 ENSG00000133321 Retinoic acid receptor responder (tazarotene induced) 3 11 63536809-63546462 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all fallopian tube: 164.2 -HRASLS2 FLJ20556 ENSG00000133328 HRAS-like suppressor 2 11 63552770-63563383 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058997 Approved Approved Mitochondria Tissue enhanced 0 duodenum: 69.6;small intestine: 47.5 rectum: 14.7 -MYH11 SMHC, SMMHC ENSG00000133392 Myosin, heavy chain 11, smooth muscle 16 15703135-15857033 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002302, HPA014539, HPA015310 Supported Approved Plasma membrane
Cytosol Tissue enhanced 0 seminal vesicle: 1365.9;smooth muscle: 1008.5 prostate: 841.6 -FOPNL C16orf63, DKFZp686N1651, FLJ31153, FOR20, PHSECRG2 ENSG00000133393 FGFR1OP N-terminal like 16 15865720-15888625 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040599 Supported Supported Centrosome Expressed in all thyroid gland: 53.7 -MED10 L6, MGC5309, NUT2, TRG20 ENSG00000133398 Mediator complex subunit 10 5 6371881-6378594 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042795, HPA054188 Supported Nucleoplasm Expressed in all cerebral cortex: 44.9 -PDZD2 KIAA0300, PDZK3 ENSG00000133401 PDZ domain containing 2 5 31639410-32110931 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB020784, HPA036503, HPA036504, HPA064387 Uncertain Approved Plasma membrane
Cytosol Mixed ovary: 18.2 -MORC2 AC004542.C22.1, KIAA0852, ZCW3, ZCWCC1 ENSG00000133422 MORC family CW-type zinc finger 2 22 30925130-30968298 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000436 Supported Supported Nucleus
Cytosol Expressed in all testis: 65.4 -LARGE KIAA0609 ENSG00000133424 Like-glycosyltransferase 22 33162226-33922841 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 43.4 -GSTT2B GSTT2P ENSG00000133433 Glutathione S-transferase theta 2B (gene/pseudogene) 22 23957414-23961186 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000750 Uncertain Supported Nucleoplasm
Cytosol Tissue enriched 7 breast: 402.7 adrenal gland: 60.9 -MYO18B BK125H2.1 ENSG00000133454 Myosin XVIIIB 22 25742144-26031041 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA000953 Uncertain Supported Nucleoplasm
Centrosome Group enriched 9 heart muscle: 46.0;skeletal muscle: 52.5 testis: 5.7 -SLC2A11 GLUT10, GLUT11 ENSG00000133460 Solute carrier family 2 (facilitated glucose transporter), member 11 22 23856703-23886309 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042960, HPA071184 Uncertain Uncertain Nucleus
Cell Junctions Mixed parathyroid gland: 10.7 -C1QTNF6 CTRP6, ZACRP6 ENSG00000133466 C1q and tumor necrosis factor related protein 6 22 37180167-37199385 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002042 Supported Approved Nucleus Tissue enhanced 0 endometrium: 52.2;placenta: 41.1 gallbladder: 13.5 -GGT2 GGT ENSG00000133475 Gamma-glutamyltransferase 2 22 21207973-21227637 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045635, HPA047534, HPA065444 Supported Approved Vesicles Tissue enhanced 0 lung: 1.3;thyroid gland: 1.5 breast: 0.9 -FAM83F ENSG00000133477 Family with sequence similarity 83, member F 22 39994949-40043529 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051207, HPA064657 Approved Approved Nucleus
Mitochondria Tissue enhanced 0 testis: 21.6 skin: 16.6 -SEC14L4 dJ130H16.5, TAP3 ENSG00000133488 SEC14-like lipid binding 4 22 30488913-30505711 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069748 Approved Centrosome Group enriched 8 bone marrow: 5.0;liver: 10.3;lung: 6.9;parathyroid gland: 10.3;testis: 7.1 adrenal gland: 0.9 -GIMAP6 FLJ22690, IAN6 ENSG00000133561 GTPase, IMAP family member 6 7 150625375-150632648 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026715, HPA050740 Uncertain Uncertain Nucleoplasm
Cytosol Mixed spleen: 89.4 -GIMAP4 FLJ11110, HIMAP4, IAN1, IMAP4 ENSG00000133574 GTPase, IMAP family member 4 7 150567277-150573955 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019135, HPA019137, HPA027198 Supported Expressed in all spleen: 150.0 -ADCK2 MGC20727 ENSG00000133597 AarF domain containing kinase 2 7 140673153-140696261 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036036 Approved Uncertain Centrosome
Cytosol Expressed in all parathyroid gland: 26.7 -MKRN1 RNF61 ENSG00000133606 Makorin ring finger protein 1 7 140453040-140479569 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000567 Approved Nucleus
Nuclear membrane
Cytosol Expressed in all testis: 223.7 -AGAP3 CENTG3 ENSG00000133612 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 7 151085831-151144436 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012883 Approved Expressed in all cerebral cortex: 92.8 -KRBA1 KIAA1862 ENSG00000133619 KRAB-A domain containing 1 7 149714781-149734575 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021237, HPA050448 Approved Approved Nucleus
Cytosol Mixed heart muscle: 11.4 -ACTR3B ARP11, ARP3beta ENSG00000133627 ARP3 actin-related protein 3 homolog B (yeast) 7 152759749-152855378 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047016, HPA051683 Uncertain Expressed in all cerebral cortex: 51.0 -NTS ENSG00000133636 Neurotensin 12 85874295-85882992 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026664 Supported Group enriched 9 small intestine: 192.9;stomach: 44.1 lymph node: 13.6 -BTG1 ENSG00000133639 B-cell translocation gene 1, anti-proliferative 12 92140278-92145897 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005972 Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 261.6 -LRRIQ1 FLJ12303, KIAA1801 ENSG00000133640 Leucine-rich repeats and IQ motif containing 1 12 85036314-85263224 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046162 Uncertain Group enriched 7 fallopian tube: 13.5;testis: 25.4 parathyroid gland: 2.8 -C12orf29 DKFZp434N2030 ENSG00000133641 Chromosome 12 open reading frame 29 12 88033846-88050160 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039663 Uncertain Approved Vesicles Mixed esophagus: 17.2 -ATP13A3 AFURS1 ENSG00000133657 ATPase type 13A3 3 194402672-194498364 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029471 Approved Approved Nucleoli
Plasma membrane
Cytosol Expressed in all parathyroid gland: 146.4 -SFTPD COLEC7, SFTP4, SP-D ENSG00000133661 Surfactant protein D 10 79937740-79982614 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004578, HPA044582, HPA056768 Supported Tissue enriched 56 lung: 783.7 bone marrow: 13.8 -DYDC2 bA36D19.6, MGC16186 ENSG00000133665 DPY30 domain containing 2 10 80344745-80368073 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA038006, HPA038007 Supported Tissue enriched 10 fallopian tube: 151.1 testis: 14.9 -TMEM254 bA369J21.6, C10orf57, FLJ13263 ENSG00000133678 Transmembrane protein 254 10 80078646-80092557 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029105 Approved Nucleoplasm
Plasma membrane Expressed in all skin: 85.9 -TMTC1 ARG99, FLJ31400, FLJ41625, OLF ENSG00000133687 Transmembrane and tetratricopeptide repeat containing 1 12 29500840-29784759 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA016720 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 spleen: 61.6 adipose tissue: 41.5 -KRAS KRAS1, KRAS2 ENSG00000133703 Kirsten rat sarcoma viral oncogene homolog 12 25204789-25250936 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049830 Approved Expressed in all rectum: 34.1 -IPO8 IMP8, RANBP8 ENSG00000133704 Importin 8 12 30628988-30695986 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018439, HPA023765 Uncertain Supported Nucleus Expressed in all parathyroid gland: 119.5 -LARS FLJ10595, FLJ21788, HSPC192, LARS1, LEUS, RNTLS ENSG00000133706 Leucyl-tRNA synthetase 5 146113038-146182660 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036424, HPA040881 Supported Supported Nuclear bodies
Cytosol Expressed in all parathyroid gland: 69.4 -SPINK5 DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI ENSG00000133710 Serine peptidase inhibitor, Kazal type 5 5 148025683-148137289 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009067, HPA011351, CAB015347 Supported Validated Vesicles Group enriched 26 esophagus: 1134.0;skin: 384.9;tonsil: 280.7 breast: 22.7 -IMPA1 IMPA ENSG00000133731 Inositol(myo)-1(or 4)-monophosphatase 1 8 81657961-81686693 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037489 Approved Approved Nucleoplasm
Mitochondria Expressed in all testis: 71.8 -LRRCC1 CLERC, KIAA1764, VFL1 ENSG00000133739 Leucine rich repeat and coiled-coil centrosomal protein 1 8 85107147-85146076 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012893 Uncertain Tissue enhanced 0 testis: 57.4 thyroid gland: 14.1 -E2F5 ENSG00000133740 E2F transcription factor 5, p130-binding 8 85177225-85217158 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA055723 Supported Nucleus
Nucleoli Mixed lymph node: 31.3 -CA1 Car1 ENSG00000133742 Carbonic anhydrase I 8 85327608-85379014 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006558, CAB025790 Supported Group enriched 31 bone marrow: 1219.6;colon: 1039.5;rectum: 2348.0 smooth muscle: 49.1 -CCDC59 BR22, HSPC128, TAP26 ENSG00000133773 Coiled-coil domain containing 59 12 82223681-82358805 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038555 Approved Approved Nucleus
Nucleoli Expressed in all bone marrow: 27.6 -SWAP70 KIAA0640, SWAP-70 ENSG00000133789 SWAP switching B-cell complex 70kDa subunit 11 9664077-9752991 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006810 Supported Expressed in all spleen: 83.4 -ARNTL bHLHe5, BMAL1, JAP3, MOP3, PASD3 ENSG00000133794 Aryl hydrocarbon receptor nuclear translocator-like 11 13276652-13387266 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045962, HPA050938 Supported Supported Nucleoplasm
Vesicles Expressed in all testis: 27.5 -LYVE1 LYVE-1, XLKD1 ENSG00000133800 Lymphatic vessel endothelial hyaluronan receptor 1 11 10556966-10611689 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025860, HPA042953 Supported Tissue enhanced 0 adipose tissue: 155.7;placenta: 211.4 smooth muscle: 94.1 -AMPD3 ENSG00000133805 Adenosine monophosphate deaminase 3 11 10308313-10507579 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038662, HPA047408 Uncertain Validated Nuclear membrane Tissue enhanced 0 parathyroid gland: 53.6 bone marrow: 41.5 -MICALCL FLJ14966 ENSG00000133808 MICAL C-terminal like 11 12276080-12359144 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039895, HPA040438 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 skin: 17.3;testis: 13.3 lung: 10.3 -SBF2 CMT4B2, DENND7B, KIAA1766, MTMR13 ENSG00000133812 SET binding factor 2 11 9778667-10294207 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050933 Uncertain Approved Nucleoplasm
Intermediate filaments
Cytosol Expressed in all parathyroid gland: 38.3 -MICAL2 KIAA0750 ENSG00000133816 Microtubule associated monooxygenase, calponin and LIM domain containing 2 11 12094008-12263789 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030437 Approved Approved Golgi apparatus Mixed testis: 80.0 -RRAS2 TC21 ENSG00000133818 Related RAS viral (r-ras) oncogene homolog 2 11 14277926-14364506 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010420, HPA050942 Approved Approved Nucleus
Cytosol Expressed in all thyroid gland: 63.8 -HSD17B4 DBP, MFE-2, SDR8C1 ENSG00000133835 Hydroxysteroid (17-beta) dehydrogenase 4 5 119452443-119637199 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021302, HPA021311, HPA021479 Supported Validated Peroxisomes Expressed in all thyroid gland: 228.6 -ZFC3H1 CCDC131, KIAA0546, MGC23401, PSRC2 ENSG00000133858 Zinc finger, C3H1-type containing 12 71609472-71667725 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007072, HPA007151 Supported Approved Nucleoplasm
Intermediate filaments Mixed testis: 19.0 -TEX15 CT42 ENSG00000133863 Testis expressed 15 8 30831544-30890606 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036799, HPA036800 Approved Approved Nuclear speckles Group enriched 31 endometrium: 10.9;smooth muscle: 8.2;testis: 22.2 cerebral cortex: 0.4 -SARAF MGC8721, TMEM66 ENSG00000133872 Store-operated calcium entry-associated regulatory factor 8 30063012-30083208 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040400 Supported Endoplasmic reticulum
Rods & Rings Expressed in all cerebral cortex: 287.8 -RNF122 FLJ12526 ENSG00000133874 Ring finger protein 122 8 33547755-33567125 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003888 Uncertain Expressed in all fallopian tube: 21.4 -DUSP26 DUSP24, MGC1136 ENSG00000133878 Dual specificity phosphatase 26 (putative) 8 33591332-33600106 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA018221 Approved Supported Nucleus Tissue enhanced 0 cerebral cortex: 47.3;skeletal muscle: 138.7 ovary: 39.6 -DPF2 BAF45d, REQ, ubi-d4 ENSG00000133884 D4, zinc and double PHD fingers family 2 11 65333754-65353249 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020880, HPA056786 Approved Supported Nucleoplasm Expressed in all fallopian tube: 51.4 -MEN1 ENSG00000133895 Multiple endocrine neoplasia I 11 64803510-64811294 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030342 Uncertain Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 22.2 -C14orf1 ERG28, NET51 ENSG00000133935 Chromosome 14 open reading frame 1 14 75649791-75661189 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043172, HPA063568 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 77.0 -GSC ENSG00000133937 Goosecoid homeobox 14 94768216-94770230 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA075650 Approved Nucleus
Nuclear bodies Tissue enhanced 0 adipose tissue: 2.1 breast: 1.1 -C14orf159 FLJ39975 ENSG00000133943 Chromosome 14 open reading frame 159 14 91060333-91225632 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041423, HPA052932 Approved Supported Cytosol Expressed in all parathyroid gland: 81.0 -UNC79 KIAA1409 ENSG00000133958 Unc-79 homolog (C. elegans) 14 93333219-93707876 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 5.2;testis: 3.0 adrenal gland: 1.0 -NUMB C14orf41 ENSG00000133961 Numb homolog (Drosophila) 14 73275107-73463642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011478 Approved Approved Cell Junctions
Cytosol Expressed in all lung: 78.1 -CATSPERB C14orf161, FLJ14298 ENSG00000133962 Catsper channel auxiliary subunit beta 14 91580696-91780707 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035134 Uncertain Uncertain Vesicles Mixed skin: 2.7 -VRTN C14orf115, FLJ10811, vertnin ENSG00000133980 Vertebrae development associated 14 74303069-74360008 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001460 Uncertain Approved Nucleoplasm Tissue enhanced 0 epididymis: 1.8;testis: 2.9 lymph node: 0.5 -COX16 C14orf112, HSPC203 ENSG00000133983 COX16 cytochrome c oxidase assembly homolog 14 70325081-70359731 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA062659 Uncertain Supported Mitochondria Expressed in all thyroid gland: 39.5 -TTC9 KIAA0227, TTC9A ENSG00000133985 Tetratricopeptide repeat domain 9 14 70641787-70675360 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 esophagus: 44.8 fallopian tube: 15.7 -MED6 NY-REN-28 ENSG00000133997 Mediator complex subunit 6 14 70581257-70600690 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030764, HPA069039 Approved Validated Nucleoplasm Expressed in all lymph node: 29.0 -EIF2S1 EIF-2alpha, EIF2, EIF2A ENSG00000134001 Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 14 67359997-67386516 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011663, HPA064885 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 60.8 -ADAM20 ENSG00000134007 ADAM metallopeptidase domain 20 14 70522358-70535015 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA059377 Supported Tissue enriched 76 testis: 9.2 cerebral cortex: 0.1 -LOXL2 WS9-14 ENSG00000134013 Lysyl oxidase-like 2 8 23297189-23425328 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025848, HPA036257, HPA056542 Approved Approved Nucleoplasm Tissue enhanced 0 smooth muscle: 58.8 placenta: 53.0 -ELP3 FLJ10422, KAT9 ENSG00000134014 Elongator acetyltransferase complex subunit 3 8 28089673-28191156 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025812 Uncertain Expressed in all cervix: 37.6 -PEBP4 CORK1, hPEBP4, MGC22776 ENSG00000134020 Phosphatidylethanolamine-binding protein 4 8 22713251-23000000 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025064 Uncertain Tissue enhanced 0 epididymis: 462.3;lung: 173.6;skeletal muscle: 233.0 thyroid gland: 95.9 -ADAMDEC1 M12.219 ENSG00000134028 ADAM-like, decysin 1 8 24384285-24406013 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 colon: 214.7;rectum: 344.3;small intestine: 485.5 duodenum: 194.4 -CTIF KIAA0427 ENSG00000134030 CBP80/20-dependent translation initiation factor 18 48539046-48863217 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016865, HPA024801 Uncertain Supported Cytosol Mixed cerebral cortex: 24.9 -MRO B29, C18orf3, FLJ30140 ENSG00000134042 Maestro 18 50795120-50825402 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA022011 Approved Tissue enhanced 0 cerebral cortex: 27.6;kidney: 25.3;testis: 54.6 thyroid gland: 10.4 -MBD2 ENSG00000134046 Methyl-CpG binding domain protein 2 18 54151601-54224788 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037282, HPA067582, HPA067615 Approved Validated Nucleoplasm Expressed in all thyroid gland: 50.3 -IER3IP1 ENSG00000134049 Immediate early response 3 interacting protein 1 18 47152998-47176374 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010027 Supported Supported Endoplasmic reticulum Expressed in all kidney: 33.8 -MRPS36 DC47, MRP-S36 ENSG00000134056 Mitochondrial ribosomal protein S36 5 69217760-69230129 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035802, HPA056795 Supported Validated Mitochondria Expressed in all kidney: 51.8 -CCNB1 CCNB ENSG00000134057 Cyclin B1 5 69167010-69178245 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000115, CAB003804, HPA030741, HPA061448 Supported Validated Cytosol Mixed lymph node: 66.3 -CDK7 CAK, CAK1, CDKN7, MO15, STK1 ENSG00000134058 Cyclin-dependent kinase 7 5 69234795-69277430 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004364, HPA007932 Supported Mixed testis: 24.7 -CD180 LY64, Ly78, RP105 ENSG00000134061 CD180 molecule 5 67179613-67196799 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003740 Supported Tissue enhanced 0 lymph node: 27.8;tonsil: 22.2 spleen: 18.0 -IRAK2 ENSG00000134070 Interleukin-1 receptor-associated kinase 2 3 10164865-10243743 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013483, HPA050520 Uncertain Approved Vesicles Mixed bone marrow: 14.7 -CAMK1 CaMKI ENSG00000134072 Calcium/calmodulin-dependent protein kinase I 3 9757342-9769992 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB031904, HPA051409 Approved Approved Cytosol Expressed in all adrenal gland: 108.1 -THUMPD3 DKFZP434F091 ENSG00000134077 THUMP domain containing 3 3 9362842-9386791 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036170, HPA036171 Approved Approved Nucleoli
Cytosol Expressed in all testis: 107.0 -VHL VHL1 ENSG00000134086 Von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 3 10141008-10152220 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005430, HPA031631, HPA031632 Uncertain Validated Nucleoplasm
Cytosol Expressed in all lymph node: 35.2 -BHLHE40 BHLHB2, bHLHe40, DEC1, STRA13 ENSG00000134107 Basic helix-loop-helix family, member e40 3 4979116-4985323 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028922 Uncertain Supported Nuclear bodies Expressed in all esophagus: 230.8 -ARL8B ARL10C, FLJ10702, Gie1 ENSG00000134108 ADP-ribosylation factor-like 8B 3 5122220-5180912 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038759, HPA040515, HPA045924 Approved Expressed in all cerebral cortex: 119.0 -EDEM1 EDEM, KIAA0212 ENSG00000134109 ER degradation enhancer, mannosidase alpha-like 1 3 5187646-5219957 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029565 Uncertain Approved Endoplasmic reticulum Expressed in all lymph node: 48.3 -CNTN6 NB-3 ENSG00000134115 Contactin 6 3 1092576-1404217 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016645 Uncertain Tissue enhanced 0 lung: 4.6;thyroid gland: 17.4 cerebral cortex: 4.1 -CHL1 CALL, FLJ44930, L1CAM2, MGC132578 ENSG00000134121 Cell adhesion molecule L1-like 3 196596-409417 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003345, CAB026120 Supported Tissue enriched 5 cerebral cortex: 112.2 ovary: 20.9 -MEIS2 HsT18361, MRG1 ENSG00000134138 Meis homeobox 2 15 36889204-37101299 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003256, CAB004999 Supported Approved Nucleoplasm
Cytosol Mixed endometrium: 63.8 -DPH6 ATPBD4, MGC14798 ENSG00000134146 Diphthamine biosynthesis 6 15 35217345-35546193 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042976, HPA055496 Approved Validated Nucleus
Nucleoli Expressed in all thyroid gland: 18.0 -KATNBL1 C15orf29, FLJ22557 ENSG00000134152 Katanin p80 subunit B-like 1 15 34140674-34210096 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062573 Approved Approved Nucleus
Midbody
Mitotic spindle Expressed in all placenta: 46.5 -EMC7 C11orf3, C15orf24 ENSG00000134153 ER membrane protein complex subunit 7 15 34084017-34101948 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010029, HPA047572 Approved Approved Nucleoplasm Expressed in all testis: 129.1 -TRPM1 CSNB1C, LTRPC1, MLSN1 ENSG00000134160 Transient receptor potential cation channel, subfamily M, member 1 15 31001061-31161273 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014779, HPA014785 Approved Uncertain Nucleoplasm
Cytosol Group enriched 27 skin: 4.8;testis: 2.5 kidney: 0.1 -GNAT2 ACHM4 ENSG00000134183 Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 1 109603267-109619929 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 6 testis: 3.7 placenta: 0.6 -GSTM1 GST1, H-B, MU ENSG00000134184 Glutathione S-transferase mu 1 1 109687814-109709039 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022669, CAB047357, HPA048652, HPA055972, HPA055973 Approved Approved Mitochondria Tissue enhanced 0 liver: 315.8 parathyroid gland: 228.7 -PRPF38B FLJ10330, NET1 ENSG00000134186 Pre-mRNA processing factor 38B 1 108692323-108701803 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053255 Approved Expressed in all lymph node: 52.4 -REG4 GISP, REG-IV, RELP ENSG00000134193 Regenerating islet-derived family, member 4 1 119794018-119811660 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025867, HPA046555 Supported Group enriched 9 colon: 222.4;duodenum: 246.1;rectum: 304.0;small intestine: 676.7 appendix: 41.2 -TSPAN2 FLJ12082, TSN2, TSPAN-2 ENSG00000134198 Tetraspanin 2 1 115048011-115089500 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015640 Uncertain Approved Nucleoplasm Tissue enhanced 0 endometrium: 71.2;smooth muscle: 64.0 seminal vesicle: 40.1 -TSHB ENSG00000134200 Thyroid stimulating hormone, beta 1 115029824-115034309 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 endometrium: 1.7 seminal vesicle: 1.0 -GSTM5 ENSG00000134201 Glutathione S-transferase mu 5 1 109712255-109775428 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048652, HPA055972, HPA055973 Approved Approved Mitochondria Group enriched 6 breast: 828.8;ovary: 220.4 fallopian tube: 83.6 -GSTM3 GST5 ENSG00000134202 Glutathione S-transferase mu 3 (brain) 1 109733932-109741038 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017130, HPA035190, CAB040583, HPA055972 Supported Supported Nucleoli
Cytosol Expressed in all testis: 718.1 -SYT6 ENSG00000134207 Synaptotagmin VI 1 114089291-114153919 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058362 Uncertain Vesicles Tissue enhanced 0 cerebral cortex: 6.5 kidney: 1.5 -VAV3 ENSG00000134215 Vav 3 guanine nucleotide exchange factor 1 107571160-107965144 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002012 Uncertain Tissue enhanced 0 kidney: 90.1 skin: 58.8 -CHIA AMCase, CHIT2, TSA1902 ENSG00000134216 Chitinase, acidic 1 111290862-111320566 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059193 Approved Group enriched 11 lung: 15.6;stomach: 7.9 testis: 1.1 -PSRC1 DDA3 ENSG00000134222 Proline/serine-rich coiled-coil 1 1 109279556-109283186 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049315, HPA056561 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 36.6 testis: 14.0 -HMGCS2 ENSG00000134240 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1 119747996-119768905 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027423, HPA027442, CAB032906 Supported Supported Mitochondria Tissue enhanced 0 liver: 1268.1 colon: 368.8 -PTPN22 Lyp, Lyp1, Lyp2, PTPN8 ENSG00000134242 Protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1 113813811-113871759 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004912, CAB012209, HPA013350 Approved Uncertain Nucleoplasm
Vesicles
Plasma membrane Tissue enhanced 0 bone marrow: 24.9 lymph node: 23.6 -SORT1 Gp95, NT3 ENSG00000134243 Sortilin 1 1 109309568-109397951 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006889, CAB011498 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Expressed in all epididymis: 166.9 -WNT2B WNT13, XWNT2 ENSG00000134245 Wingless-type MMTV integration site family, member 2B 1 112466541-112530165 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060696, HPA066368 Uncertain Approved Vesicles Mixed seminal vesicle: 20.0 -PTGFRN CD315, CD9P-1, EWI-F, FLJ11001, FPRP, KIAA1436, SMAP-6 ENSG00000134247 Prostaglandin F2 receptor inhibitor 1 116910057-116990358 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017074 Approved Mixed smooth muscle: 68.4 -LAMTOR5 HBXIP, MGC71071, XIP ENSG00000134248 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 1 110401249-110407942 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006812 Approved Supported Cytosol Expressed in all kidney: 428.5 -ADAM30 svph4 ENSG00000134249 ADAM metallopeptidase domain 30 1 119893533-119896495 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026080 Uncertain Tissue enriched 468 testis: 46.8 adipose tissue: 0.0 -NOTCH2 ENSG00000134250 Notch 2 1 119911553-120069626 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046392, HPA048743 Uncertain Supported Nucleoplasm
Plasma membrane Expressed in all cervix: 46.5 -TRIM45 FLJ13181, RNF99 ENSG00000134253 Tripartite motif containing 45 1 117111060-117122587 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030266, HPA054308 Uncertain Supported Cytokinetic bridge
Cytosol Mixed fallopian tube: 14.3 -CEPT1 ENSG00000134255 Choline/ethanolamine phosphotransferase 1 1 111139627-111185102 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all spleen: 41.5 -CD101 IGSF2, V7 ENSG00000134256 CD101 molecule 1 117001750-117036476 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057763 Approved Tissue enhanced 0 lung: 9.6 small intestine: 7.0 -VTCN1 B7-H4, B7H4, B7S1, B7X, FLJ22418 ENSG00000134258 V-set domain containing T cell activation inhibitor 1 1 117143587-117210960 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054200 Approved Approved Plasma membrane
Cell Junctions
Focal adhesion sites Tissue enhanced 0 breast: 127.6;fallopian tube: 50.8 cervix: 21.9 -NGF NGFB ENSG00000134259 Nerve growth factor (beta polypeptide) 1 115285918-115338236 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 ovary: 12.3 smooth muscle: 5.9 -AP4B1 BETA-4, SPG47 ENSG00000134262 Adaptor-related protein complex 4, beta 1 subunit 1 113894748-113905201 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028162, HPA028652 Approved Approved Vesicles Expressed in all spleen: 19.5 -NAPG ENSG00000134265 N-ethylmaleimide-sensitive factor attachment protein, gamma 18 10525905-10552761 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008208, HPA011389 Approved Approved Plasma membrane
Cytosol Expressed in all cerebral cortex: 50.6 -SPIRE1 KIAA1135, spir-1 ENSG00000134278 Spire-type actin nucleation factor 1 18 12446512-12658134 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040737, HPA040942 Uncertain Approved Nucleoplasm
Cytosol Mixed testis: 63.2 -PPHLN1 ENSG00000134283 Periphilin 1 12 42238447-42459715 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038902, HPA038903 Supported Validated Nucleoplasm
Golgi apparatus Expressed in all testis: 101.7 -FKBP11 FKBP19 ENSG00000134285 FK506 binding protein 11, 19 kDa 12 48921518-48926474 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041709 Approved Approved Centrosome Mixed pancreas: 60.7 -ARF3 ENSG00000134287 ADP-ribosylation factor 3 12 48935723-48957551 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all cerebral cortex: 403.8 -TMEM106C MGC5576 ENSG00000134291 Transmembrane protein 106C 12 47963569-47968878 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047204 Supported Expressed in all parathyroid gland: 165.9 -SLC38A2 ATA2, KIAA1382, SAT2, SNAT2 ENSG00000134294 Solute carrier family 38, member 2 12 46358189-46372867 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035180 Approved Approved Vesicles Expressed in all skin: 239.3 -YWHAQ 14-3-3, HS1 ENSG00000134308 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 2 9583972-9631014 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007925, CAB010286 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 399.2 -KIDINS220 ARMS ENSG00000134313 Kinase D-interacting substrate, 220kDa 2 8725278-8837630 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014790 Supported Approved Nucleoplasm Expressed in all parathyroid gland: 99.9 -GRHL1 LBP-32, MGR, TFCP2L2 ENSG00000134317 Grainyhead-like transcription factor 1 2 9951693-10002277 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005798, HPA006420 Approved Validated Nucleus
Golgi apparatus
Vesicles Tissue enhanced 0 esophagus: 111.9;skin: 106.8 parathyroid gland: 51.7 -ROCK2 ENSG00000134318 Rho-associated, coiled-coil containing protein kinase 2 2 11179761-11348330 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007459, CAB008666, HPA044109 Approved Supported Cytosol Expressed in all adipose tissue: 40.7 -RSAD2 cig5, vig1, viperin ENSG00000134321 Radical S-adenosyl methionine domain containing 2 2 6865806-6898239 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041160, HPA049409 Approved Supported Nucleoli fibrillar center
Endoplasmic reticulum Mixed spleen: 18.0 -MYCN bHLHe37, MYCNOT, N-myc, NMYC ENSG00000134323 V-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2 15940564-15947007 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057420 Approved Nucleus
Nucleoli Tissue enhanced 0 placenta: 9.6 cerebral cortex: 5.3 -LPIN1 KIAA0188 ENSG00000134324 Lipin 1 2 11677595-11827409 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038021 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all testis: 101.7 -CMPK2 TYKi, UMP-CMPK2 ENSG00000134326 Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 2 6840570-6866635 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041430 Approved Approved Mitochondria Mixed spleen: 5.6 -IAH1 ENSG00000134330 Isoamyl acetate-hydrolyzing esterase 1 homolog 2 9473658-9496543 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040523 Supported Nucleoplasm Expressed in all testis: 121.1 -LDHA ENSG00000134333 Lactate dehydrogenase A 11 18394388-18408425 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015336 Approved Supported Vesicles
Cytosol Expressed in all adipose tissue: 499.8 -SAA2 ENSG00000134339 Serum amyloid A2 11 18239223-18248643 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adipose tissue: 708.4;cervix, uterine: 411.1;liver: 580.7 appendix: 215.3 -ANO3 C11orf25, DYT23, GENX-3947, TMEM16C ENSG00000134343 Anoctamin 3 11 26309599-26663288 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA041629 Uncertain Tissue enriched 6 epididymis: 61.3 cerebral cortex: 10.6 -IL6ST CD130, GP130 ENSG00000134352 Interleukin 6 signal transducer 5 55935095-55994993 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010558, CAB025784 Uncertain Supported Golgi apparatus
Plasma membrane Expressed in all placenta: 327.1 -FST FS ENSG00000134363 Follistatin 5 53480409-53487134 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018155, CAB026025 Uncertain Mixed liver: 32.8 -CFHR4 CFHL4, FHR-4, FHR4 ENSG00000134365 Complement factor H-related 4 1 196850241-196918972 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 257 liver: 78.1 testis: 0.3 -NAV1 DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1 ENSG00000134369 Neuron navigator 1 1 201622885-201826969 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012302, HPA018127, HPA027887 Approved Approved Microtubules Mixed cerebral cortex: 31.8 -CDC73 C1orf28, FIHP, HRPT1, HRPT2, parafibromin ENSG00000134371 Cell division cycle 73 1 193122017-193253901 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016359, HPA030772 Supported Supported Nucleus
Cytosol Expressed in all thyroid gland: 32.0 -TIMM17A TIM17, TIM17A ENSG00000134375 Translocase of inner mitochondrial membrane 17 homolog A (yeast) 1 201955491-201970661 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010083 Approved Supported Nucleoplasm
Mitochondria Expressed in all thyroid gland: 62.9 -CRB1 LCA8, RP12 ENSG00000134376 Crumbs family member 1, photoreceptor morphogenesis associated 1 197268204-197478455 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061250, HPA063127 Approved Uncertain Vesicles Group enriched 10 cerebral cortex: 12.1;testis: 4.9 ovary: 0.8 -CFHR5 CFHL5, FHR-5, FHR5 ENSG00000134389 Complement factor H-related 5 1 196977556-197009674 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038915, HPA040726 Supported Tissue enriched 495 liver: 88.0 testis: 0.1 -ERN2 IRE1b ENSG00000134398 Endoplasmic reticulum to nucleus signaling 2 16 23690309-23713500 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016558 Uncertain Group enriched 6 cervix, uterine: 26.7;colon: 27.8;duodenum: 12.7;gallbladder: 25.2;rectum: 23.4;small intestine: 10.1;stomach: 49.9 appendix: 3.9 -RPS15A S15A ENSG00000134419 Ribosomal protein S15a 16 18781295-18790383 Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047103 Supported Expressed in all breast: 4769.2 -RAX RX ENSG00000134438 Retina and anterior neural fold homeobox 18 59267035-59274086 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Not detected prostate: 0.1 -NARS NARS1 ENSG00000134440 Asparaginyl-tRNA synthetase 18 57600656-57622213 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034257, HPA040017 Supported Validated Cytosol Expressed in all parathyroid gland: 151.7 -GRP ENSG00000134443 Gastrin-releasing peptide 18 59220168-59230774 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lung: 13.3;thyroid gland: 10.2 parathyroid gland: 3.9 -KIAA1468 FLJ33841, HsT3308, HsT885 ENSG00000134444 KIAA1468 18 62187258-62307829 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039708, HPA040038 Approved Approved Nucleoplasm
Cytosol Expressed in all skin: 24.7 -FBXO18 FBH1, Fbx18, FLJ14590 ENSG00000134452 F-box protein, helicase, 18 10 5890203-5937594 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002844 Supported Expressed in all fallopian tube: 46.4 -RBM17 MGC14439, SPF45 ENSG00000134453 RNA binding motif protein 17 10 6088987-6117457 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037477, HPA037478 Supported Supported Nucleoplasm Expressed in all placenta: 103.9 -IL2RA CD25, IDDM10, IL2R ENSG00000134460 Interleukin 2 receptor, alpha 10 6010689-6062325 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002419, HPA054622 Supported Tissue enhanced 0 adipose tissue: 23.9;appendix: 20.4;lymph node: 20.7 tonsil: 12.5 -ANKRD16 DKFZP434N1511 ENSG00000134461 Ankyrin repeat domain 16 10 5861617-5889906 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037920, HPA037921 Uncertain Approved Endoplasmic reticulum Mixed testis: 9.9 -ECHDC3 FLJ20909 ENSG00000134463 Enoyl CoA hydratase domain containing 3 10 11742366-11764070 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038306 Supported Approved Nucleus
Nucleoli
Mitochondria Expressed in all adipose tissue: 76.3 -IL15RA CD215, IL-15RA ENSG00000134470 Interleukin 15 receptor, alpha 10 5937569-5978187 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB026215 Approved Uncertain Plasma membrane
Cytosol Expressed in all gallbladder: 33.5 -CCNH CycH, p34, p37 ENSG00000134480 Cyclin H 5 87391494-87413019 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019416, HPA044138 Approved Supported Nucleoplasm Expressed in all testis: 88.5 -HRH4 AXOR35, GPCR105, GPRv53, H4R, HH4R ENSG00000134489 Histamine receptor H4 18 24460629-24479957 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035009 Uncertain Not detected skin: 0.7 -TMEM241 C18orf45, FLJ44259, MGC11386 ENSG00000134490 Transmembrane protein 241 18 23197144-23437961 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA029489, HPA059922 Uncertain Approved Golgi apparatus
Vesicles Mixed cerebral cortex: 4.3 -KCTD1 C18orf5 ENSG00000134504 Potassium channel tetramerization domain containing 1 18 26454910-26657401 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed fallopian tube: 72.0 -CABLES1 FLJ35924, HsT2563 ENSG00000134508 Cdk5 and Abl enzyme substrate 1 18 23134564-23260467 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064114 Approved Nuclear speckles Tissue enhanced 0 parathyroid gland: 60.0 lung: 32.5 -DOCK2 KIAA0209 ENSG00000134516 Dedicator of cytokinesis 2 5 169637247-170083382 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036469 Supported Mixed lymph node: 52.8 -EMP1 CL-20, TMP ENSG00000134531 Epithelial membrane protein 1 12 13196716-13219939 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051931, HPA056250 Approved Nucleoplasm Expressed in all esophagus: 2208.3 -SOX5 L-SOX5, MGC35153 ENSG00000134532 SRY (sex determining region Y)-box 5 12 23529500-23951032 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060499 Supported Nucleoplasm Tissue enhanced 0 testis: 58.3 cerebral cortex: 11.7 -RERG MGC15754 ENSG00000134533 RAS-like, estrogen-regulated, growth inhibitor 12 15107783-15348675 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041387 Approved Mixed endometrium: 140.7 -SLCO1B1 LST-1, OATP-C, OATP1B1, SLC21A6 ENSG00000134538 Solute carrier organic anion transporter family, member 1B1 12 21131202-21239246 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050892 Supported Tissue enriched 249 liver: 307.4 breast: 1.2 -KLRD1 CD94 ENSG00000134539 Killer cell lectin-like receptor subfamily D, member 1 12 10226058-10329600 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069688 Uncertain Tissue enhanced 0 spleen: 19.1 lymph node: 6.8 -KLRC1 CD159a, NKG2, NKG2-A, NKG2-B ENSG00000134545 Killer cell lectin-like receptor subfamily C, member 1 12 10442264-10454685 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058052 Approved Plasma membrane Mixed spleen: 10.3 -SPX C12orf39, MGC10946, NPQ, spexin ENSG00000134548 Spexin hormone 12 21526307-21537377 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 6 adipose tissue: 53.7;placenta: 13.3 thyroid gland: 6.0 -PRH2 Pr ENSG00000134551 Proline-rich protein HaeIII subfamily 2 12 10929236-10932341 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 1863 salivary gland: 16666.5 ovary: 8.9 -LRP4 CLSS, LRP-4, MEGF7, SOST2 ENSG00000134569 Low density lipoprotein receptor-related protein 4 11 46856868-46918642 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011934, HPA012300 Approved Uncertain Nucleus
Nucleoli
Mitochondria Tissue enhanced 0 cerebral cortex: 35.5;skin: 38.0 parathyroid gland: 12.9 -MYBPC3 CMH4, FHC, MYBP-C ENSG00000134571 Myosin binding protein C, cardiac 11 47331397-47352702 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040147, HPA043898 Supported Tissue enriched 472 heart muscle: 684.8 testis: 1.4 -DDB2 DDBB, FLJ34321, UV-DDB2, XPE ENSG00000134574 Damage-specific DNA binding protein 2, 48kDa 11 47214465-47239240 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025912, HPA058406 Supported Supported Nucleoplasm
Cell Junctions Expressed in all skin: 53.8 -ACP2 LAP ENSG00000134575 Acid phosphatase 2, lysosomal 11 47239302-47248906 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all duodenum: 42.4 -USP26 ENSG00000134588 Ubiquitin specific peptidase 26 X 133024631-133097109 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 5 testis: 1.1 breast: 0.2 -FAM127A CXX1, Mar8, MAR8C, Mart8 ENSG00000134590 Family with sequence similarity 127, member A X 135032366-135033546 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all cerebral cortex: 241.1 -RAB33A RabS10 ENSG00000134594 RAB33A, member RAS oncogene family X 130171649-130184870 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059737 Uncertain Approved Vesicles Tissue enhanced 0 cerebral cortex: 32.0 lymph node: 9.2 -SOX3 PHP ENSG00000134595 SRY (sex determining region Y)-box 3 X 140502987-140505503 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054720, HPA075003 Validated Nucleoplasm Tissue enriched 7 fallopian tube: 11.7 testis: 1.7 -RBMX2 CGI-79, Snu17 ENSG00000134597 RNA binding motif protein, X-linked 2 X 130401969-130413343 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026609 Approved Approved Nuclear membrane
Nucleoli Expressed in all endometrium: 29.2 -STK26 MASK, MST4 ENSG00000134602 Serine/threonine protein kinase 26 X 132023265-132075943 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059921 Approved Approved Nucleus
Golgi apparatus
Centrosome
Cytosol Mixed epididymis: 67.5 -PIWIL4 FLJ36156, HIWI2, Miwi2 ENSG00000134627 Piwi-like RNA-mediated gene silencing 4 11 94543840-94621421 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036588, HPA057508 Approved Tissue enhanced 0 testis: 24.2 bone marrow: 15.5 -MTNR1B ENSG00000134640 Melatonin receptor 1B 11 92969720-92985066 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 placenta: 1.4 testis: 0.8 -PUM1 KIAA0099, PUMH1 ENSG00000134644 Pumilio RNA-binding family member 1 1 30931506-31065991 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027424, HPA027449 Approved Supported Nucleus
Cytosol Expressed in all parathyroid gland: 71.9 -SPOCD1 FLJ25348, PPP1R146 ENSG00000134668 SPOC domain containing 1 1 31790422-31816051 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031713, HPA031714, HPA031715 Approved Approved Nucleus
Nucleoli
Cytosol Tissue enhanced 0 testis: 14.1;urinary bladder: 10.3 appendix: 4.5 -YARS tyrRS, YRS, YTS ENSG00000134684 Tyrosyl-tRNA synthetase 1 32775237-32818153 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017936, HPA018950, HPA018954 Supported Validated Cytosol Expressed in all cerebral cortex: 81.7 -PHC2 EDR2, HPH2 ENSG00000134686 Polyhomeotic homolog 2 (Drosophila) 1 33323623-33431052 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047403 Supported Supported Nucleoplasm Expressed in all smooth muscle: 86.6 -CDCA8 BOR, DasraB, FLJ12042, MESRGP ENSG00000134690 Cell division cycle associated 8 1 37692418-37709719 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028120, HPA028258, HPA028783, CAB040294 Supported Validated Nucleoli
Cytokinetic bridge Tissue enhanced 0 testis: 36.5 lymph node: 23.3 -GNL2 HUMAUANTIG, Ngp-1, Nog2, Nug2 ENSG00000134697 Guanine nucleotide binding protein-like 2 (nucleolar) 1 37566816-37595935 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027163, HPA060026 Approved Validated Nucleoli Expressed in all testis: 55.3 -AGO4 EIF2C4, FLJ20033, hAGO4, KIAA1567 ENSG00000134698 Argonaute RISC catalytic component 4 1 35808172-35857890 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012179, HPA068896 Approved Validated Nucleoplasm
Nuclear bodies
Cytosol Expressed in all skin: 24.5 -HOOK1 HK1 ENSG00000134709 Hook microtubule-tethering protein 1 1 59814786-59876378 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018537, HPA018820 Supported Tissue enhanced 0 parathyroid gland: 54.2 testis: 30.0 -CYP2J2 ENSG00000134716 Cytochrome P450, family 2, subfamily J, polypeptide 2 1 59893308-59926790 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 liver: 74.3;small intestine: 94.1 heart muscle: 54.3 -BTF3L4 MGC23908 ENSG00000134717 Basic transcription factor 3-like 4 1 52056125-52090716 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067026 Approved Approved Nucleus
Cytosol Expressed in all thyroid gland: 72.4 -ZCCHC11 KIAA0191, PAPD3, TUT4 ENSG00000134744 Zinc finger, CCHC domain containing 11 1 52408282-52553487 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027412, HPA027973 Supported Supported Nucleoli
Cytosol Expressed in all parathyroid gland: 59.0 -PRPF38A FLJ14936, Prp38 ENSG00000134748 Pre-mRNA processing factor 38A 1 52404564-52420839 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053099, HPA058407 Uncertain Validated Nucleus Expressed in all endometrium: 23.0 -DSC2 CDHF2, DSC3 ENSG00000134755 Desmocollin 2 18 31058840-31102415 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011911, HPA012615 Supported Tissue enhanced 0 esophagus: 187.4 parathyroid gland: 60.8 -DSG3 CDHF6 ENSG00000134757 Desmoglein 3 18 31447795-31478702 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046864, HPA056863, CAB069880 Supported Tissue enriched 5 esophagus: 350.9 tonsil: 68.5 -RNF138 NARF, STRIN ENSG00000134758 Ring finger protein 138, E3 ubiquitin protein ligase 18 32091855-32131561 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041101 Approved Mitochondria Expressed in all testis: 166.5 -ELP2 FLJ10879, STATIP1, StIP ENSG00000134759 Elongator acetyltransferase complex subunit 2 18 36129444-36180556 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002996, CAB020835 Approved Validated Nucleus
Cytosol Expressed in all ovary: 59.6 -DSG1 CDHF4, DSG ENSG00000134760 Desmoglein 1 18 31318089-31357029 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009394, HPA022128 Supported Tissue enriched 20 skin: 727.4 esophagus: 36.5 -DSC3 CDHF3, DSC, DSC1, DSC2, DSC4 ENSG00000134762 Desmocollin 3 18 30990008-31042815 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037328, HPA049265, HPA073937 Supported Validated Plasma membrane
Cell Junctions Group enriched 11 esophagus: 119.5;skin: 455.7 tonsil: 25.9 -DSC1 CDHF1 ENSG00000134765 Desmocollin 1 18 31129236-31162856 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012891 Uncertain Tissue enriched 15 skin: 273.7 heart muscle: 18.7 -DTNA D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3 ENSG00000134769 Dystrobrevin, alpha 18 34493290-34891844 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015196, HPA071177 Supported Approved Nucleoplasm
Cell Junctions
Intermediate filaments Tissue enhanced 0 cerebral cortex: 197.7 heart muscle: 100.9 -FHOD3 FHOS2, FLJ22297, FLJ22717, KIAA1695 ENSG00000134775 Formin homology 2 domain containing 3 18 36297714-36780055 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021827, HPA024696 Uncertain Tissue enhanced 0 heart muscle: 88.2;seminal vesicle: 85.7 epididymis: 48.8 -TPGS2 C18orf10, DKFZP586M1523, HsT3006 ENSG00000134779 Tubulin polyglutamylase complex subunit 2 18 36777647-36829216 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040596, HPA040617, HPA061753 Uncertain Supported Nucleoli Expressed in all testis: 364.7 -DAGLA C11orf11, DAGLALPHA, KIAA0659, NSDDR ENSG00000134780 Diacylglycerol lipase, alpha 11 61680433-61747001 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062497 Approved Tissue enriched 6 cerebral cortex: 18.6 colon: 3.1 -SLC43A3 DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1 ENSG00000134802 Solute carrier family 43, member 3 11 57406954-57427580 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030551 Approved Expressed in all thyroid gland: 121.6 -TIMM10 TIM10, TIM10A ENSG00000134809 Translocase of inner mitochondrial membrane 10 homolog (yeast) 11 57528463-57530803 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039946 Supported Validated Mitochondria Expressed in all epididymis: 52.0 -GIF IF, IFMH, INF, TCN3 ENSG00000134812 Gastric intrinsic factor (vitamin B synthesis) 11 59829268-59845501 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039908, HPA040774 Supported Tissue enriched 1634 stomach: 1264.8 cerebral cortex: 0.7 -DHX34 DDX34, KIAA0134 ENSG00000134815 DEAH (Asp-Glu-Ala-His) box polypeptide 34 19 47349281-47382704 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042159, HPA043558 Uncertain Uncertain Nucleus
Intermediate filaments Mixed testis: 20.9 -APLNR AGTRL1, APJ, APJR, FLJ90771 ENSG00000134817 Apelin receptor 11 57233577-57237314 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025842 Approved Group enriched 5 cerebral cortex: 82.9;placenta: 145.6;spleen: 164.2 adipose tissue: 24.9 -FADS2 D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13 ENSG00000134824 Fatty acid desaturase 2 11 61792980-61867354 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006741 Approved Expressed in all adrenal gland: 416.6 -TMEM258 C11orf10 ENSG00000134825 Transmembrane protein 258 11 61768501-61792802 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044602 Approved Approved Plasma membrane
Cytosol Expressed in all epididymis: 429.6 -TCN1 TC1, TCI ENSG00000134827 Transcobalamin I (vitamin B12 binding protein, R binder family) 11 59852800-59866575 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 124.0;gallbladder: 256.1;salivary gland: 317.5 stomach: 76.1 -C5AR2 C5L2, GPR77 ENSG00000134830 Complement component 5a receptor 2 19 47332147-47347327 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA016629 Uncertain Tissue enhanced 0 spleen: 9.9 appendix: 6.1 -TMEM165 GDT1, TMPT27, TPARL ENSG00000134851 Transmembrane protein 165 4 55395957-55453397 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038299 Supported Supported Golgi apparatus
Vesicles Expressed in all placenta: 86.4 -CLOCK bHLHe8, KAT13D, KIAA0334 ENSG00000134852 Clock circadian regulator 4 55427903-55547138 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001867, HPA027565 Supported Validated Nucleoplasm Mixed testis: 26.3 -PDGFRA CD140a, GAS9, PDGFR2 ENSG00000134853 Platelet-derived growth factor receptor, alpha polypeptide 4 54229097-54298247 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004947, CAB018143 Supported Supported Nucleus
Plasma membrane
Cell Junctions Expressed in all ovary: 222.0 -GGACT A2LD1 ENSG00000134864 Gamma-glutamylamine cyclotransferase 13 100530164-100589528 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065320 Approved Tissue enriched 6 kidney: 75.5 testis: 12.4 -COL4A2 DKFZp686I14213, FLJ22259 ENSG00000134871 Collagen, type IV, alpha 2 13 110305812-110513027 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010751, HPA029118 Supported Supported Vesicles Tissue enhanced 0 placenta: 827.3 smooth muscle: 396.9 -CLDN10 CPETRL3, OSP-L ENSG00000134873 Claudin 10 13 95433604-95579759 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB012969, HPA042348 Supported Tissue enhanced 0 kidney: 161.8 gallbladder: 111.0 -DZIP1 DZIP, KIAA0996 ENSG00000134874 DAZ interacting zinc finger protein 1 13 95578202-95644703 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054891, HPA057272, HPA070194 Uncertain Supported Nucleoplasm
Microtubule organizing center
Cytosol Tissue enhanced 0 testis: 57.2 ovary: 30.4 -UBAC2 FLJ30548, PHGDHL1, RP11-178C10.1 ENSG00000134882 UBA domain containing 2 13 99200774-99386434 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013448 Approved Approved Cytosol Expressed in all thyroid gland: 35.6 -ARGLU1 FLJ10154 ENSG00000134884 Arginine and glutamate rich 1 13 106541673-106568164 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034962, HPA056792 Supported Validated Nucleoplasm
Mitochondria Expressed in all endometrium: 328.7 -BIVM FLJ20159 ENSG00000134897 Basic, immunoglobulin-like variable motif containing 13 102799049-102841535 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA050126 Approved Supported Nucleoplasm Expressed in all kidney: 17.8 -ERCC5 ERCM2, XPGC ENSG00000134899 Excision repair cross-complementation group 5 13 102844844-102876001 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045845, HPA050374 Supported Approved Nucleoplasm Expressed in all spleen: 38.2 -TPP2 TPPII ENSG00000134900 Tripeptidyl peptidase II 13 102597003-102679958 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021069, HPA049630 Approved Supported Nuclear bodies
Cytosol Expressed in all testis: 66.5 -KDELC1 EP58, MGC5302 ENSG00000134901 KDEL (Lys-Asp-Glu-Leu) containing 1 13 102784281-102799007 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020780, HPA043946, HPA064398 Approved Supported Nucleus Mixed smooth muscle: 17.4 -CARS2 FLJ12118 ENSG00000134905 Cysteinyl-tRNA synthetase 2, mitochondrial (putative) 13 110641412-110713603 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041776 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all cervix: 28.3 -ARHGAP32 GC-GAP, GRIT, KIAA0712, MGC1892, RICS ENSG00000134909 Rho GTPase activating protein 32 11 128965060-129279324 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038382, HPA038389, HPA061505 Approved Approved Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus Expressed in all cerebral cortex: 44.2 -STT3A ITM1, MGC9042, STT3-A, TMC ENSG00000134910 STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 11 125591712-125625215 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030735 Approved Uncertain Nucleoplasm
Vesicles
Cytosol Tissue enriched 6 parathyroid gland: 1111.5 epididymis: 173.1 -ADAMTS8 ADAM-TS8, FLJ41712, METH2 ENSG00000134917 ADAM metallopeptidase with thrombospondin type 1 motif, 8 11 130404925-130428993 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA066349 Approved Tissue enhanced 0 appendix: 11.2;lung: 15.6 seminal vesicle: 5.5 -ACRV1 D11S4365, SP-10, SPACA2 ENSG00000134940 Acrosomal vesicle protein 1 11 125671522-125681123 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038718, HPA038719 Supported Tissue enriched 37 testis: 152.8 epididymis: 4.1 -ETS1 ETS-1, EWSR2, FLJ10768 ENSG00000134954 V-ets avian erythroblastosis virus E26 oncogene homolog 1 11 128458761-128587558 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002575, HPA063230 Supported Validated Nucleoplasm Expressed in all lymph node: 324.7 -SLC37A2 FLJ00171 ENSG00000134955 Solute carrier family 37 (glucose-6-phosphate transporter), member 2 11 125063067-125090312 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014948 Uncertain Mixed adrenal gland: 24.8 -KLB ENSG00000134962 Klotho beta 4 39406853-39451536 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021136 Uncertain Tissue enhanced 0 adipose tissue: 20.6;liver: 9.1 testis: 5.1 -TMED7 CGI-109, FLJ90481, p24g3, p24gamma3 ENSG00000134970 Transmembrane p24 trafficking protein 7 5 115613508-115632992 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008960, CAB025883 Supported Expressed in all thyroid gland: 138.5 -APC DP2, DP2.5, DP3, PPP1R46 ENSG00000134982 Adenomatous polyposis coli 5 112707498-112846239 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013349, CAB025994 Approved Tissue enhanced 0 cerebral cortex: 60.3 parathyroid gland: 19.5 -NREP C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17 ENSG00000134986 Neuronal regeneration related protein 5 111662621-111997464 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA000545 Approved Approved Vesicles Expressed in all cerebral cortex: 175.6 -WDR36 GLC1G, TA-WDRP, UTP21 ENSG00000134987 WD repeat domain 36 5 111091716-111130502 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037796, HPA037797 Supported Supported Nucleoli Expressed in all thyroid gland: 17.1 -OSTF1 bA235O14.1, OSF, SH3P2 ENSG00000134996 Osteoclast stimulating factor 1 9 75088543-75147265 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020514 Approved Supported Cytosol Expressed in all spleen: 124.6 -RFK FLJ11149, RIFK ENSG00000135002 Riboflavin kinase 9 76385517-76394517 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023259, CAB033887, HPA057163 Approved Approved Golgi apparatus Expressed in all cerebral cortex: 37.9 -UBQLN1 DA41, DSK2, PLIC-1, XDRP1 ENSG00000135018 Ubiquilin 1 9 83659963-83708203 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037256, HPA054143 Supported Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 114.1 -NAA35 bA379P1.1, FLJ21613, FLJ22643, MAK10 ENSG00000135040 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 9 85941146-86022298 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021547, HPA051586 Approved Supported Vesicles Expressed in all testis: 37.8 -C9orf40 FLJ10110 ENSG00000135045 Chromosome 9 open reading frame 40 9 74946581-74952886 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042167 Approved Approved Nucleoplasm
Centrosome
Cytosol Mixed testis: 16.9 -ANXA1 ANX1, LPC1 ENSG00000135046 Annexin A1 9 73151757-73170393 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011271, HPA011272, CAB013023, CAB035987, CAB058693 Supported Validated Nucleoplasm
Plasma membrane
Cytosol Tissue enriched 6 esophagus: 7577.8 tonsil: 1266.5 -CTSL CTSL1, FLJ31037 ENSG00000135047 Cathepsin L 9 87725519-87731393 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000459 Supported Expressed in all placenta: 744.0 -TMEM2 ENSG00000135048 Transmembrane protein 2 9 71683366-71816690 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044889 Approved Approved Vesicles
Cytosol Expressed in all placenta: 93.9 -AGTPBP1 CCP1, KIAA1035, Nna1 ENSG00000135049 ATP/GTP binding protein 1 9 85546539-85742029 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057208 Approved Approved Nucleoli
Vesicles Expressed in all bone marrow: 39.3 -GOLM1 bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73 ENSG00000135052 Golgi membrane protein 1 9 86026146-86100173 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010638, HPA011929, CAB015341 Supported Validated Golgi apparatus Expressed in all stomach: 406.6 -FAM189A2 C9orf61, X123 ENSG00000135063 Family with sequence similarity 189, member A2 9 69324572-69392455 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029411, HPA057207 Approved Tissue enhanced 0 thyroid gland: 100.5 cervix: 64.0 -PSAT1 PSA ENSG00000135069 Phosphoserine aminotransferase 1 9 78297143-78330093 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB014882, CAB040567, HPA042924 Supported Validated Cytosol Tissue enhanced 0 cerebral cortex: 186.5 liver: 138.5 -ISCA1 HBLD2, hIscA, ISA1, MGC4276 ENSG00000135070 Iron-sulfur cluster assembly 1 9 86264546-86282538 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042789 Uncertain Expressed in all cerebral cortex: 73.6 -ADAM19 MLTNB ENSG00000135074 ADAM metallopeptidase domain 19 5 157395534-157575775 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055537 Approved Vesicles Mixed lymph node: 34.9 -HAVCR2 CD366, FLJ14428, Tim-3, TIM3, TIMD3 ENSG00000135077 Hepatitis A virus cellular receptor 2 5 157085832-157142869 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010505, CAB026003, HPA047581 Supported Supported Nucleoplasm Mixed spleen: 24.0 -CCNJL FLJ14166 ENSG00000135083 Cyclin J-like 5 160251652-160345396 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA049970 Approved Approved Nuclear speckles Tissue enhanced 0 testis: 19.4 lung: 10.3 -TAOK3 DPK, JIK, MAP3K18 ENSG00000135090 TAO kinase 3 12 118149801-118372945 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017160 Approved Approved Mitochondria Expressed in all cerebral cortex: 49.0 -USP30 FLJ40511, MGC10702 ENSG00000135093 Ubiquitin specific peptidase 30 12 109023089-109088026 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016952 Approved Expressed in all testis: 25.5 -SDS SDH ENSG00000135094 Serine dehydratase 12 113392445-113426301 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039230 Uncertain Approved Mitochondria
Cytosol Tissue enriched 18 liver: 190.0 cerebral cortex: 10.5 -MSI1 ENSG00000135097 Musashi RNA-binding protein 1 12 120341330-120369180 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064401 Approved Nucleoplasm
Vesicles
Cytosol Tissue enhanced 0 cerebral cortex: 17.6;testis: 14.7 skeletal muscle: 7.2 -HNF1A HCF-1A, HNF1, LFB1, MODY3, TCF1 ENSG00000135100 HNF1 homeobox A 12 120978543-121002512 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB010430, HPA035231 Supported Supported Nucleoplasm Tissue enhanced 0 duodenum: 15.9;kidney: 10.1;small intestine: 16.0 liver: 5.8 -FBXO21 FBX21, KIAA0875 ENSG00000135108 F-box protein 21 12 117141988-117190531 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062411, HPA071452 Approved Approved Mitochondria Expressed in all fallopian tube: 202.3 -TBX3 TBX3-ISO, UMS, XHL ENSG00000135111 T-box 3 12 114670254-114684164 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005799 Approved Nucleoplasm
Cytosol Tissue enhanced 0 adrenal gland: 201.8 prostate: 114.3 -OASL p59OASL, TRIP14 ENSG00000135114 2'-5'-oligoadenylate synthetase-like 12 121019111-121039242 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001474 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 bone marrow: 35.5;stomach: 22.4 lung: 20.0 -HRK DP5 ENSG00000135116 Harakiri, BCL2 interacting protein 12 116856144-116881441 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB025973 Uncertain Group enriched 9 cerebral cortex: 13.4;thyroid gland: 6.4 testis: 1.1 -RNFT2 FLJ14627, TMEM118 ENSG00000135119 Ring finger protein, transmembrane 2 12 116738178-116853631 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA064161 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 15.4 testis: 6.1 -P2RX4 P2X4 ENSG00000135124 Purinergic receptor P2X, ligand gated ion channel, 4 12 121209857-121234106 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039494 Approved Approved Actin filaments
Cytosol Mixed placenta: 33.5 -CCDC64 FLJ26450 ENSG00000135127 Coiled-coil domain containing 64 12 119989869-120094494 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA061116 Approved Approved Nucleoplasm
Vesicles
Cytosol Tissue enhanced 0 kidney: 73.5;skin: 58.8 epididymis: 45.0 -DTX1 hDx-1 ENSG00000135144 Deltex 1, E3 ubiquitin ligase 12 113056709-113098028 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051249, HPA055275 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Mixed parathyroid gland: 13.6 -TRAFD1 FLN29 ENSG00000135148 TRAF-type zinc finger domain containing 1 12 112125501-112153609 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039254, HPA039266 Supported Approved Nucleoplasm
Cytosol Expressed in all testis: 53.6 -DMTF1 DMP1, DMTF, hDMP1, MRUL ENSG00000135164 Cyclin D binding myb-like transcription factor 1 7 87152361-87196337 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023846 Supported Supported Nucleoplasm Expressed in all testis: 83.7 -OCM2 ENSG00000135175 Oncomodulin 2 7 97984684-97991169 Predicted intracellular proteins No evidence No evidence No evidence HPA046422 Uncertain Not detected testis: 0.1 -TMEM243 C7orf23, MGC4175, MM-TRAG ENSG00000135185 Transmembrane protein 243, mitochondrial 7 87196160-87220587 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014918 Uncertain Expressed in all thyroid gland: 103.3 -CCDC146 KIAA1505 ENSG00000135205 Coiled-coil domain containing 146 7 77122434-77329533 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020082, HPA020105 Uncertain Approved Golgi apparatus
Vesicles Tissue enhanced 0 fallopian tube: 57.0;testis: 39.7 thyroid gland: 13.7 -TMEM60 C7orf35, DC32 ENSG00000135211 Transmembrane protein 60 7 77793728-77798580 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062625 Approved Expressed in all parathyroid gland: 55.3 -CD36 FAT, GP3B, GP4, GPIV, SCARB3 ENSG00000135218 CD36 molecule (thrombospondin receptor) 7 80369575-80679277 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002018, CAB025866 Supported Expressed in all adipose tissue: 1614.0 -UGT2A3 FLJ21934 ENSG00000135220 UDP glucuronosyltransferase 2 family, polypeptide A3 4 68928463-68951791 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045108 Supported Tissue enhanced 0 duodenum: 84.3;gallbladder: 46.5;kidney: 46.4;small intestine: 87.8 rectum: 24.3 -CSN2 CASB ENSG00000135222 Casein beta 4 69955256-69961007 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041036 Supported Tissue enriched 347 breast: 349.2 salivary gland: 1.0 -UGT2B28 ENSG00000135226 UDP glucuronosyltransferase 2 family, polypeptide B28 4 69280487-69423402 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045108 Uncertain Tissue enriched 12 breast: 268.9 gallbladder: 21.7 -PNPLA8 IPLA2-2, IPLA2G, iPLA2gamma ENSG00000135241 Patatin-like phospholipase domain containing 8 7 108470422-108569666 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020083 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all adrenal gland: 63.4 -HILPDA C7orf68, FLJ21076, HIG-2, HIG2 ENSG00000135245 Hypoxia inducible lipid droplet-associated 7 128455849-128458418 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA010515 Approved Supported Nucleoplasm
Lipid droplets Expressed in all esophagus: 108.2 -FAM71F1 FAM137A, NYD-SP18 ENSG00000135248 Family with sequence similarity 71, member F1 7 128709061-128731743 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA020636 Uncertain Cytosol Tissue enriched 147 testis: 82.4 epididymis: 0.5 -RINT1 FLJ11785, RINT-1 ENSG00000135249 RAD50 interactor 1 7 105532085-105567677 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019875, HPA031646 Approved Approved Golgi apparatus Expressed in all testis: 18.9 -SRPK2 SFRSK2 ENSG00000135250 SRSF protein kinase 2 7 105110704-105399308 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015522, HPA020876 Approved Supported Nucleus
Cytosol Group enriched 5 cerebral cortex: 108.6;testis: 196.7 endometrium: 29.8 -KCP CRIM2, FLJ33365, NET67 ENSG00000135253 Kielin/chordin-like protein 7 128862451-128910719 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 kidney: 2.7;seminal vesicle: 3.2 gallbladder: 1.5 -TES DKFZP586B2022, TESS-2, TESTIN ENSG00000135269 Testin LIM domain protein 7 116210493-116258783 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015269, HPA018123 Approved Supported Plasma membrane
Cell Junctions
Focal adhesion sites
Cytosol Expressed in all seminal vesicle: 269.2 -MDFIC HIC ENSG00000135272 MyoD family inhibitor domain containing 7 114922154-115019916 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030716 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all adipose tissue: 47.6 -MTO1 ENSG00000135297 Mitochondrial tRNA translation optimization 1 6 73461578-73509236 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030230, HPA030232 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 24.8 -ADGRB3 BAI3, KIAA0550 ENSG00000135298 Adhesion G protein-coupled receptor B3 6 68635367-69389511 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 10 cerebral cortex: 53.2 adrenal gland: 5.2 -ANKRD6 KIAA0957 ENSG00000135299 Ankyrin repeat domain 6 6 89433170-89633834 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB020693, HPA035694, HPA064642 Approved Supported Vesicles Mixed cerebral cortex: 23.7 -HTR1B 5-HT1B, 5-HT1DB, HTR1D2, S12 ENSG00000135312 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 6 77462205-77463464 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA028808 Approved Uncertain Plasma membrane Tissue enhanced 0 placenta: 13.7;stomach: 5.8 cerebral cortex: 2.8 -KHDC1 bA257K9.4, C6orf147, C6orf148, Em:AC019205.8, MGC10818, NDG1 ENSG00000135314 KH homology domain containing 1 6 73241314-73310365 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029032 Approved Approved Mitochondria
Cytosol Tissue enhanced 0 cerebral cortex: 10.0 testis: 6.7 -CEP162 C6orf84, KIAA1009, QN1 ENSG00000135315 Centrosomal protein 162kDa 6 84124241-84227635 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030170, HPA030171, HPA030172, HPA030173 Supported Validated Plasma membrane
Cytosol Mixed testis: 15.7 -SYNCRIP dJ3J17.2, GRY-RBP, hnRNP-Q, HNRNPQ, HNRPQ1, NSAP1 ENSG00000135316 Synaptotagmin binding, cytoplasmic RNA interacting protein 6 85607785-85643792 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010895, HPA041275 Supported Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 131.5 -SNX14 RGS-PX2 ENSG00000135317 Sorting nexin 14 6 85505496-85594156 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017639 Approved Supported Cytosol Expressed in all testis: 154.6 -NT5E CALJA, CD73, eN, eNT, NT5 ENSG00000135318 5'-nucleotidase, ecto (CD73) 6 85449584-85495791 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017357 Approved Supported Plasma membrane
Cytosol Tissue enhanced 0 cervix, uterine: 171.7 smooth muscle: 104.9 -MRAP2 bA51G5.2, C6orf117 ENSG00000135324 Melanocortin 2 receptor accessory protein 2 6 84033756-84090881 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 21.1 fallopian tube: 13.3 -EPHA7 Hek11 ENSG00000135333 EPH receptor A7 6 93240020-93419547 Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010496 Uncertain Tissue enriched 13 parathyroid gland: 250.5 prostate: 19.4 -AKIRIN2 C6orf166, dJ486L4.2, FLJ10342 ENSG00000135334 Akirin 2 6 87675072-87702209 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064239 Supported Nucleoplasm Expressed in all spleen: 59.2 -ORC3 IMAGE50150, LATHEO, ORC3L ENSG00000135336 Origin recognition complex, subunit 3 6 87590067-87667453 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039553, HPA053748 Supported Validated Nucleoplasm Expressed in all testis: 48.7 -LCA5 C6orf152 ENSG00000135338 Leber congenital amaurosis 5 6 79484991-79537458 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA029053, HPA029055 Approved Tissue enhanced 0 parathyroid gland: 47.5 fallopian tube: 17.2 -MAP3K7 MEKK7, TAK1 ENSG00000135341 Mitogen-activated protein kinase kinase kinase 7 6 90513573-90587045 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007633 Approved Approved Nuclear speckles
Cytosol Expressed in all parathyroid gland: 28.6 -CGA FSHA, GPHa, GPHA1, HCG, LHA, TSHA ENSG00000135346 Glycoprotein hormones, alpha polypeptide 6 87085498-87095406 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB023350, HPA029698 Supported Tissue enriched 22 placenta: 652.2 stomach: 29.5 -GJA10 CX62 ENSG00000135355 Gap junction protein, alpha 10, 62kDa 6 89894469-89896120 Predicted membrane proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level HPA021145 Uncertain Not detected testis: 0.3 -PRR5L FLJ14213, PROTOR-2 ENSG00000135362 Proline rich 5 like 11 36296288-36465204 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA070174 Approved Cytokinetic bridge
Cytosol Tissue enhanced 0 spleen: 51.9 colon: 35.6 -LMO2 RBTN2, RBTNL1, RHOM2, TTG2 ENSG00000135363 LIM domain only 2 (rhombotin-like 1) 11 33858576-33892289 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB016258, HPA029285 Approved Approved Nucleoplasm
Cytosol Mixed spleen: 26.2 -PHF21A BHC80, BM-006, KIAA1696 ENSG00000135365 PHD finger protein 21A 11 45929323-46121178 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023580 Uncertain Expressed in all testis: 43.7 -NAT10 FLJ10774, FLJ12179, hALP, KIAA1709, NET43 ENSG00000135372 N-acetyltransferase 10 (GCN5-related) 11 34105602-34147670 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB035546, HPA057576, HPA071628 Supported Validated Nucleoli
Midbody Expressed in all parathyroid gland: 35.0 -EHF ESE3, ESEJ ENSG00000135373 Ets homologous factor 11 34621093-34661057 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA050923, HPA060734 Approved Supported Nucleoplasm
Golgi apparatus Mixed esophagus: 229.2 -ELF5 ENSG00000135374 E74-like factor 5 (ets domain transcription factor) 11 34478793-34513805 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA062706 Supported Nucleoplasm Tissue enhanced 0 breast: 173.4;salivary gland: 64.6 seminal vesicle: 41.8 -PRRG4 TMG4 ENSG00000135378 Proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 11 32829943-32858123 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009040, HPA024566 Uncertain Approved Golgi apparatus Mixed skin: 25.1 -CAPRIN1 caprin-1, GPIAP1, M11S1, RNG105 ENSG00000135387 Cell cycle associated protein 1 11 34051683-34101156 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018126, HPA063617 Approved Validated Cytosol Expressed in all testis: 248.2 -ATP5G2 ENSG00000135390 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 12 53632726-53677408 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051469 Approved Expressed in all fallopian tube: 769.8 -DNAJC14 DNAJ, DRIP78, FLJ32792, HDJ3, LIP6 ENSG00000135392 DnaJ (Hsp40) homolog, subfamily C, member 14 12 55820960-55830824 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA017653 Approved Expressed in all parathyroid gland: 49.6 -CD63 ME491, MLA1, TSPAN30 ENSG00000135404 CD63 molecule 12 55725323-55729707 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010088, CAB026356 Supported Supported Vesicles Expressed in all epididymis: 1712.6 -PRPH NEF4, PRPH1 ENSG00000135406 Peripherin 12 49293252-49298686 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002437, HPA039277, HPA063887 Supported Tissue enhanced 0 adrenal gland: 20.7 appendix: 11.7 -AVIL ADVIL, DOC6, FLJ12386, p92 ENSG00000135407 Advillin 12 57797376-57818704 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058864 Approved Mixed skin: 6.7 -AMHR2 MISR2, MISRII ENSG00000135409 Anti-Mullerian hormone receptor, type II 12 53423855-53431534 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060228, HPA069636 Approved Vesicles Tissue enhanced 0 adrenal gland: 32.2;ovary: 40.8 testis: 10.1 -LACRT LACRITIN ENSG00000135413 Lacritin 12 54630811-54634895 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 salivary gland: 4.6 breast: 0.7 -GDF11 BMP-11 ENSG00000135414 Growth differentiation factor 11 12 55743280-55757278 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA060985, HPA069609 Approved Approved Vesicles Mixed seminal vesicle: 13.5 -GLS2 GA, GLS, hLGA, LGA ENSG00000135423 Glutaminase 2 (liver, mitochondrial) 12 56470944-56488414 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038608 Uncertain Tissue enriched 11 liver: 80.4 cerebral cortex: 7.3 -ITGA7 ENSG00000135424 Integrin, alpha 7 12 55684568-55716043 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008427 Uncertain Approved Plasma membrane
Cytosol Tissue enhanced 0 adipose tissue: 154.2 smooth muscle: 135.5 -TESPA1 KIAA0748 ENSG00000135426 Thymocyte expressed, positive selection associated 1 12 54948018-54984746 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058823 Approved Tissue enhanced 0 lymph node: 47.4 tonsil: 35.9 -FAM186B C12orf25, DKFZP434J0113 ENSG00000135436 Family with sequence similarity 186, member B 12 49582885-49605639 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039736, HPA040028 Uncertain Tissue enriched 32 testis: 75.9 parathyroid gland: 2.3 -RDH5 HSD17B9, RDH1, SDR9C5 ENSG00000135437 Retinol dehydrogenase 5 (11-cis/9-cis) 12 55720367-55724705 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063345 Approved Vesicles
Cytosol Tissue enhanced 0 adipose tissue: 97.7 liver: 29.9 -AGAP2 CENTG1 ENSG00000135439 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 12 57723761-57742157 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023474 Approved Supported Nucleus
Nucleoli
Mitochondria Tissue enriched 7 cerebral cortex: 145.0 lymph node: 20.1 -BLOC1S1 BLOS1, BORCS1, GCN5L1 ENSG00000135441 Biogenesis of lysosomal organelles complex-1, subunit 1 12 55716037-55720087 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021381 Approved Expressed in all fallopian tube: 211.6 -KRT85 Hb-5, KRTHB5 ENSG00000135443 Keratin 85, type II 12 52360006-52367481 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049778 Supported Not detected testis: 0.8 -CDK4 PSK-J3 ENSG00000135446 Cyclin-dependent kinase 4 12 57747727-57756013 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006024, CAB069405 Approved Supported Nucleus
Nuclear membrane
Nucleoli
Cytosol Expressed in all endometrium: 120.2 -PPP1R1A ENSG00000135447 Protein phosphatase 1, regulatory (inhibitor) subunit 1A 12 54575387-54588659 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007811, HPA041542 Approved Tissue enhanced 0 adipose tissue: 252.8;skeletal muscle: 291.3 kidney: 74.0 -TROAP TASTIN ENSG00000135451 Trophinin associated protein 12 49323236-49331731 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044102 Uncertain Tissue enhanced 0 bone marrow: 32.1;testis: 45.9 tonsil: 14.2 -TSPAN31 SAS ENSG00000135452 Tetraspanin 31 12 57738013-57750211 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057489 Approved Expressed in all thyroid gland: 73.1 -B4GALNT1 beta1-4GalNAc-T, GALGT, SPG26 ENSG00000135454 Beta-1,4-N-acetyl-galactosaminyl transferase 1 12 57623410-57633355 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008968, HPA015128 Supported Tissue enriched 7 cerebral cortex: 26.3 seminal vesicle: 3.7 -TFCP2 CP2, LBP-1C, LSF, TFCP2C ENSG00000135457 Transcription factor CP2 12 51093663-51173134 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070247 Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 43.6 -COQ10A FLJ32452 ENSG00000135469 Coenzyme Q10A 12 56266858-56270966 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA068931 Approved Endoplasmic reticulum
Golgi apparatus
Cytosol Expressed in all skeletal muscle: 97.2 -FAIM2 KIAA0950, LFG, LFG2, LIFEGUARD, NMP35, TMBIM2 ENSG00000135472 Fas apoptotic inhibitory molecule 2 12 49866896-49904217 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018790, HPA048800 Supported Approved Intermediate filaments Tissue enriched 7 cerebral cortex: 370.8 adrenal gland: 56.0 -PAN2 hPAN2, KIAA0710, USP52 ENSG00000135473 PAN2 poly(A) specific ribonuclease subunit 12 56316223-56334053 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 32.0 -ESPL1 ESP1, KIAA0165, SEPA ENSG00000135476 Extra spindle pole bodies like 1, separase 12 53268299-53293643 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012185 Uncertain Supported Nucleoplasm
Vesicles Tissue enhanced 0 esophagus: 11.4;testis: 10.6 lymph node: 4.9 -KRT7 CK7, K2C7, K7, SCL ENSG00000135480 Keratin 7, type II 12 52232520-52252186 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000028, HPA007272 Supported Tissue enhanced 0 thyroid gland: 652.7 placenta: 279.9 -ZC3H10 FLJ14451, ZC3HDC10 ENSG00000135482 Zinc finger CCCH-type containing 10 12 56118159-56127514 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039236, HPA062265 Uncertain Approved Vesicles Mixed testis: 10.4 -HNRNPA1 ALS20, hnRNP-A1, hnRNPA1, HNRPA1 ENSG00000135486 Heterogeneous nuclear ribonucleoprotein A1 12 54280193-54287088 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001609, HPA001666, HPA005812, HPA007185, CAB010894 Supported Validated Nucleoplasm Expressed in all ovary: 1913.9 -SLC26A10 ENSG00000135502 Solute carrier family 26, member 10 12 57619527-57626151 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044719 Uncertain Not detected endometrium: 0.5 -ACVR1B ActRIB, ACVRLK4, ALK4, SKR2 ENSG00000135503 Activin A receptor, type IB 12 51951667-51997078 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026126, HPA063761 Approved Validated Cytosol Expressed in all parathyroid gland: 53.7 -OS9 ERLEC2, OS-9 ENSG00000135506 Osteosarcoma amplified 9, endoplasmic reticulum lectin 12 57693955-57721557 Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011518, HPA013694 Supported Expressed in all parathyroid gland: 290.9 -MIP AQP0, LIM1, MP26 ENSG00000135517 Major intrinsic protein of lens fiber 12 56449502-56469166 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA014940 Supported Tissue enhanced 0 testis: 1.2 cerebral cortex: 0.2 -KCNH3 BEC1, elk2, Kv12.2 ENSG00000135519 Potassium channel, voltage gated eag related subfamily H, member 3 12 49539157-49558308 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051088 Uncertain Approved Nucleus
Mitochondria Group enriched 5 cerebral cortex: 24.3;fallopian tube: 7.1;parathyroid gland: 4.9 adrenal gland: 2.2 -LTV1 C6orf93, dJ468K18.4, FLJ14909 ENSG00000135521 LTV1 ribosome biogenesis factor 6 143843344-143863812 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030159, HPA030160, HPA030161 Approved Validated Nucleoplasm
Cytosol Expressed in all testis: 38.4 -MAP7 E-MAP-115 ENSG00000135525 Microtubule-associated protein 7 6 136342281-136550819 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029712, HPA029713 Supported Supported Microtubules
Cytosol Mixed cerebral cortex: 53.1 -CD164 DFNA66, MGC-24, MUC-24 ENSG00000135535 CD164 molecule, sialomucin 6 109366514-109382559 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA010636 Uncertain Expressed in all thyroid gland: 608.3 -LACE1 AFG1 ENSG00000135537 Lactation elevated 1 6 108294894-108526796 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030154, HPA030155, HPA030659 Approved Approved Plasma membrane
Cytosol Tissue enhanced 0 testis: 17.5 parathyroid gland: 8.1 -NHSL1 bA43P8.1, C6orf63, KIAA1357 ENSG00000135540 NHS-like 1 6 138422043-138692571 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029966, HPA029967, HPA029968 Uncertain Approved Nucleoplasm
Cytosol Mixed small intestine: 26.3 -AHI1 FLJ20069, JBTS3, ORF1 ENSG00000135541 Abelson helper integration site 1 6 135283532-135497776 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031698, HPA046684 Approved Approved Centrosome Mixed testis: 51.0 -HEY2 bHLHb32, HERP1, HESR2 ENSG00000135547 Hes-related family bHLH transcription factor with YRPW motif 2 6 125747664-125761269 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA030205, HPA074851 Approved Approved Nuclear bodies
Aggresome Mixed fallopian tube: 21.5 -PKIB PRKACN2 ENSG00000135549 Protein kinase (cAMP-dependent, catalytic) inhibitor beta 6 122471917-122726373 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA030156 Approved Tissue enhanced 0 colon: 90.7;placenta: 84.8 parathyroid gland: 76.4 -TAAR5 PNR ENSG00000135569 Trace amine associated receptor 5 6 132588673-132589686 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA051703 Uncertain Not detected epididymis: 0.0 -NMBR BB1 ENSG00000135577 Neuromedin B receptor 6 142058330-142088799 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA026665 Supported Plasma membrane
Cytosol Group enriched 5 fallopian tube: 1.3;testis: 2.6 cerebral cortex: 0.3 -SMPD2 ISC1, nSMase ENSG00000135587 Sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 6 109440763-109443919 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018110, HPA018125 Uncertain Approved Vesicles
Plasma membrane
Cell Junctions Mixed testis: 55.6 -MICAL1 DKFZp434B1517, FLJ11937, FLJ21739, MICAL, NICAL ENSG00000135596 Microtubule associated monooxygenase, calponin and LIM domain containing 1 6 109444062-109465968 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030175, HPA030176, HPA030178 Approved Mixed bone marrow: 39.5 -REPS1 ENSG00000135597 RALBP1 associated Eps domain containing 1 6 138903493-138988261 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029961, HPA029962 Approved Approved Vesicles
Plasma membrane
Cytosol Expressed in all testis: 65.9 -STX11 ENSG00000135604 Syntaxin 11 6 144150526-144188370 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007992, HPA076253 Approved Supported Nuclear bodies
Mitochondria Tissue enhanced 0 bone marrow: 101.0 adipose tissue: 32.0 -TEC PSCTK4 ENSG00000135605 Tec protein tyrosine kinase 4 48135783-48269864 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005733, HPA024657 Approved Supported Plasma membrane Mixed epididymis: 4.9 -PRADC1 C2orf7, hPAP21, MGC13004, PAP21 ENSG00000135617 Protease-associated domain containing 1 2 73228006-73233238 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051066 Approved Expressed in all heart muscle: 43.9 -SEMA4F SEMAM, SEMAW ENSG00000135622 Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 2 74654228-74683853 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA065969 Approved Nucleus
Plasma membrane
Centrosome Mixed cerebral cortex: 14.2 -CCT7 Ccth, Nip7-1 ENSG00000135624 Chaperonin containing TCP1, subunit 7 (eta) 2 73233420-73253021 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008425 Approved Approved Cytosol Expressed in all testis: 285.7 -EGR4 NGFI-C, PAT133 ENSG00000135625 Early growth response 4 2 73290929-73293705 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028983 Approved Group enriched 29 cerebral cortex: 9.7;testis: 3.2 appendix: 0.2 -RAB11FIP5 GAF1, KIAA0857, pp75, RIP11 ENSG00000135631 RAB11 family interacting protein 5 (class I) 2 73073382-73156721 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036406, HPA036407 Supported Validated Vesicles
Microtubule organizing center Tissue enhanced 0 testis: 39.1 parathyroid gland: 22.5 -SMYD5 NN8-4AG, RAI15, RRG1, ZMYND23 ENSG00000135632 SMYD family member 5 2 73214222-73227237 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015514, HPA049002 Uncertain Approved Mitochondria Expressed in all ovary: 34.1 -DYSF FER1L1, LGMD2B ENSG00000135636 Dysferlin 2 71453722-71686768 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002510, HPA017071, HPA021945 Supported Supported Plasma membrane
Microtubule organizing center Mixed skeletal muscle: 32.8 -CCDC142 FLJ14397 ENSG00000135637 Coiled-coil domain containing 142 2 74471986-74483408 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056946 Approved Mixed parathyroid gland: 5.7 -EMX1 ENSG00000135638 Empty spiracles homeobox 1 2 72916260-72936071 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA006230, HPA006421 Uncertain Approved Nucleoli Tissue enhanced 0 cerebral cortex: 8.3;kidney: 15.5;parathyroid gland: 5.1 testis: 2.6 -KCNMB4 ENSG00000135643 Potassium channel subfamily M regulatory beta subunit 4 12 70366276-70434292 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072287 Approved Cytosol Group enriched 8 adrenal gland: 19.6;cerebral cortex: 38.2 placenta: 3.7 -USP15 KIAA0529, UNPH4 ENSG00000135655 Ubiquitin specific peptidase 15 12 62260338-62417431 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006237, HPA006428, HPA071014 Approved Validated Cytosol Expressed in all bone marrow: 121.9 -GNS ENSG00000135677 Glucosamine (N-acetyl)-6-sulfatase 12 64713445-64759447 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013695, CAB026011, HPA048508 Supported Expressed in all adrenal gland: 173.8 -CPM ENSG00000135678 Carboxypeptidase M 12 68842197-68971570 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002657, HPA077243 Uncertain Uncertain Vesicles Tissue enhanced 0 adipose tissue: 163.6 placenta: 100.2 -MDM2 HDM2, MGC5370 ENSG00000135679 MDM2 proto-oncogene, E3 ubiquitin protein ligase 12 68808172-68850686 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000086, CAB016303 Supported Supported Nucleus Expressed in all rectum: 44.3 -KLHL36 C16orf44, FLJ12543 ENSG00000135686 Kelch-like family member 36 16 84648525-84667686 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023423 Approved Approved Cytosol Expressed in all testis: 20.7 -BCO1 BCDO, BCDO1, BCMO, BCMO1, FLJ10730 ENSG00000135697 Beta-carotene oxygenase 1 16 81238448-81291142 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043811 Uncertain Actin filaments
Microtubule organizing center Tissue enhanced 0 duodenum: 8.9;small intestine: 15.1 kidney: 3.3 -MPHOSPH6 MPP6 ENSG00000135698 M-phase phosphoprotein 6 16 82147798-82170226 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003674, HPA026948 Approved Supported Nucleus
Nucleoli Expressed in all breast: 90.9 -CHST5 FLJ22167, I-GLCNAC-6-ST ENSG00000135702 Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 16 75528535-75535247 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043804 Approved Group enriched 14 colon: 46.8;duodenum: 88.4;rectum: 60.8;small intestine: 85.3 stomach: 4.9 -KIAA0513 ENSG00000135709 KIAA0513 16 85027751-85094230 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA012866, HPA014431 Supported Uncertain Nucleoplasm
Cytosol Tissue enriched 7 cerebral cortex: 102.9 adrenal gland: 14.9 -DYNC1LI2 DNCLI2 ENSG00000135720 Dynein, cytoplasmic 1, light intermediate chain 2 16 66720893-66751798 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057201 Approved Centrosome
Cytosol Expressed in all cerebral cortex: 141.9 -FBXL8 Fbl8 ENSG00000135722 F-box and leucine-rich repeat protein 8 16 67159931-67164570 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035587, HPA035588 Uncertain Approved Golgi apparatus Expressed in all prostate: 25.7 -FHOD1 FHOS ENSG00000135723 Formin homology 2 domain containing 1 16 67229387-67247658 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024468 Approved Supported Cytosol Tissue enhanced 0 spleen: 63.4 skeletal muscle: 40.4 -CCDC102A MGC10992 ENSG00000135736 Coiled-coil domain containing 102A 16 57512178-57536599 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040598, HPA040958 Supported Approved Nucleoplasm
Nuclear bodies Mixed seminal vesicle: 5.3 -SLC9A5 NHE5 ENSG00000135740 Solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 16 67237683-67272190 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA041004, HPA041329 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 spleen: 7.8 cerebral cortex: 2.5 -AGT SERPINA8 ENSG00000135744 Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1 230702523-230714297 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001557, CAB025798 Supported Tissue enhanced 0 cerebral cortex: 227.1;liver: 649.2 gallbladder: 134.3 -PCNXL2 FLJ11383, KIAA0435 ENSG00000135749 Pecanex-like 2 (Drosophila) 1 232983435-233295713 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA013815, HPA014427 Uncertain Approved Endoplasmic reticulum Mixed cerebral cortex: 14.0 -KCNK1 DPK, K2p1.1, TWIK-1 ENSG00000135750 Potassium channel, two pore domain subfamily K, member 1 1 233614004-233672512 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016049, CAB022588 Approved Approved Vesicles Mixed cerebral cortex: 46.6 -URB2 KIAA0133, NET10, NPA2 ENSG00000135763 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 1 229626234-229660199 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA008902, HPA046788 Uncertain Validated Nucleoli Mixed testis: 10.6 -EGLN1 C1orf12, HIFPH2, PHD2, SM-20, ZMYND6 ENSG00000135766 Egl-9 family hypoxia-inducible factor 1 1 231363751-231425044 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022129 Approved Approved Cytosol Expressed in all parathyroid gland: 29.5 -CAPN9 GC36, nCL-4 ENSG00000135773 Calpain 9 1 230747384-230802003 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020398, CAB033483 Supported Tissue enhanced 0 rectum: 25.6;stomach: 58.8 colon: 14.6 -COG2 LDLC ENSG00000135775 Component of oligomeric golgi complex 2 1 230642489-230693982 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA076994 Approved Golgi apparatus Expressed in all parathyroid gland: 75.7 -ABCB10 EST20237, M-ABC2, MTABC2 ENSG00000135776 ATP-binding cassette, sub-family B (MDR/TAP), member 10 1 229516582-229558695 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB044063, CAB044065, HPA055175 Uncertain Expressed in all bone marrow: 36.6 -NTPCR C1orf57, HCR-NTPase, MGC13186 ENSG00000135778 Nucleoside-triphosphatase, cancer-related 1 232950605-232983882 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028125, HPA054304 Uncertain Approved Cytosol Mixed parathyroid gland: 11.2 -TAF5L PAF65B ENSG00000135801 TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 1 229593111-229626047 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067941 Supported Nuclear speckles
Cytoplasmic bodies Expressed in all placenta: 20.4 -GLUL GLNS ENSG00000135821 Glutamate-ammonia ligase 1 182381704-182392206 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007316, HPA007571, CAB008636 Approved Supported Mitochondria
Cytosol Expressed in all adipose tissue: 1001.1 -STX6 ENSG00000135823 Syntaxin 6 1 180972712-181023121 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038557, HPA038558 Approved Validated Nucleoplasm
Golgi apparatus Mixed cerebral cortex: 30.3 -RGS8 MGC119067, MGC119068, MGC119069 ENSG00000135824 Regulator of G-protein signaling 8 1 182641816-182684576 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 cerebral cortex: 5.3;testis: 4.9;thyroid gland: 11.2 adrenal gland: 1.3 -RNASEL PRCA1, RNS4 ENSG00000135828 Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 1 182573634-182589256 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002633, CAB010906 Approved Supported Cytosol Mixed parathyroid gland: 17.5 -DHX9 DDX9, LKP, RHA ENSG00000135829 DEAH (Asp-Glu-Ala-His) box helicase 9 1 182839369-182887751 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011819, HPA028050, HPA055684 Supported Validated Nucleus Expressed in all parathyroid gland: 135.7 -KIAA1614 ENSG00000135835 KIAA1614 1 180913154-180951614 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA028227, HPA061684 Approved Approved Nuclear membrane
Vesicles Mixed thyroid gland: 3.0 -CEP350 CAP350, KIAA0480 ENSG00000135837 Centrosomal protein 350kDa 1 179954738-180114880 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028355, HPA028357, HPA030845 Approved Supported Centrosome Expressed in all testis: 44.8 -NPL C1orf13, DHDPS1, NPL1 ENSG00000135838 N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 1 182789293-182830384 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028345 Approved Vesicles
Plasma membrane Mixed placenta: 63.2 -FAM129A C1orf24, GIG39, NIBAN ENSG00000135842 Family with sequence similarity 129, member A 1 184790724-184974550 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028172, HPA028231, HPA028657 Approved Supported Plasma membrane
Cytosol Expressed in all heart muscle: 105.0 -PIGC ENSG00000135845 Phosphatidylinositol glycan anchor biosynthesis, class C 1 172370189-172444086 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036663 Uncertain Expressed in all epididymis: 47.0 -LAMC1 LAMB2 ENSG00000135862 Laminin, gamma 1 (formerly LAMB2) 1 183023460-183145592 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001908, HPA001909, CAB004486, CAB078163 Supported Approved Endoplasmic reticulum
Plasma membrane Tissue enhanced 0 placenta: 330.2 smooth muscle: 145.7 -RC3H1 KIAA2025, RNF198, roquin, RP5-1198E17.5 ENSG00000135870 Ring finger and CCCH-type domains 1 1 173931214-174022297 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027428, HPA027434, HPA027448 Approved Supported Plasma membrane
Cytosol Mixed bone marrow: 12.9 -GPR55 ENSG00000135898 G protein-coupled receptor 55 2 230907318-230961066 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 spleen: 5.9;testis: 9.0 tonsil: 4.6 -SP110 IFI41, IFI75 ENSG00000135899 SP110 nuclear body protein 2 230167293-230225729 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047036, HPA058554 Approved Supported Nucleus Expressed in all spleen: 64.1 -MRPL44 FLJ12701, FLJ13990 ENSG00000135900 Mitochondrial ribosomal protein L44 2 223957404-223967714 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038147, HPA038148 Approved Approved Nucleus
Plasma membrane
Mitochondria Expressed in all kidney: 37.2 -CHRND ACHRD ENSG00000135902 Cholinergic receptor, nicotinic, delta (muscle) 2 232525993-232536667 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 14 skeletal muscle: 9.6 prostate: 0.6 -PAX3 HUP2, WS1 ENSG00000135903 Paired box 3 2 222199888-222298996 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA063659, HPA069000 Uncertain Supported Nucleoplasm Group enriched 9 breast: 1.2;skeletal muscle: 1.1;skin: 3.2;testis: 2.4 prostate: 0.2 -DOCK10 KIAA0694, ZIZ3 ENSG00000135905 Dedicator of cytokinesis 10 2 224765090-225042445 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035749, HPA058106 Uncertain Approved Nucleoplasm
Cytosol Mixed spleen: 47.4 -TTLL4 KIAA0173 ENSG00000135912 Tubulin tyrosine ligase-like family member 4 2 218710845-218755416 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027091, HPA050252 Approved Approved Mitochondria Expressed in all testis: 46.7 -USP37 KIAA1594 ENSG00000135913 Ubiquitin specific peptidase 37 2 218450251-218568361 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045160 Approved Approved Nucleus
Nucleoli Mixed testis: 23.3 -HTR2B 5-HT(2B), 5-HT2B ENSG00000135914 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 2 231108230-231125118 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level CAB011448, HPA012867, HPA063658 Approved Approved Nucleoplasm Tissue enhanced 0 cervix, uterine: 31.1;endometrium: 30.0;smooth muscle: 23.0 adrenal gland: 19.1 -ITM2C BRI3, BRICD2C, E25, hRPC.1050_D_4, ITM3 ENSG00000135916 Integral membrane protein 2C 2 230864639-230879248 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 854.9 -SLC19A3 THTR2 ENSG00000135917 Solute carrier family 19 (thiamine transporter), member 3 2 227685210-227718012 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038898 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 adipose tissue: 50.1;placenta: 34.5 duodenum: 12.7 -SERPINE2 GDN, nexin, PI7, PN1, PNI ENSG00000135919 Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 2 223975112-224039319 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 placenta: 1612.5 cerebral cortex: 236.5 -DNAJB2 CMT2T, HSJ1, HSPF3 ENSG00000135924 DnaJ (Hsp40) homolog, subfamily B, member 2 2 219279267-219286900 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036268 Approved Validated Nuclear membrane Expressed in all cerebral cortex: 162.3 -WNT10A ENSG00000135925 Wingless-type MMTV integration site family, member 10A 2 218880363-218899581 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA013898 Uncertain Tissue enhanced 0 skin: 8.3 placenta: 3.9 -TMBIM1 LFG3, PP1201, RECS1 ENSG00000135926 Transmembrane BAX inhibitor motif containing 1 2 218274192-218292586 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012093, HPA070824 Approved Supported Vesicles Expressed in all esophagus: 270.8 -CYP27A1 CP27, CTX, CYP27 ENSG00000135929 Cytochrome P450, family 27, subfamily A, polypeptide 1 2 218781749-218815293 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059155 Approved Validated Mitochondria Tissue enhanced 0 liver: 278.5 lung: 98.4 -EIF4E2 4EHP, EIF4EL3, IF4e ENSG00000135930 Eukaryotic translation initiation factor 4E family member 2 2 232550052-232583644 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019253 Approved Mitochondria
Cytosol Expressed in all rectum: 76.7 -ARMC9 ARM, FLJ12584, KIAA1868, KU-MEL-1 ENSG00000135931 Armadillo repeat containing 9 2 231198546-231374837 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019041, HPA026671 Approved Approved Nucleoli
Cytosol Mixed smooth muscle: 33.7 -CAB39 CGI-66, MO25 ENSG00000135932 Calcium binding protein 39 2 230712845-230821075 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037112 Supported Approved Nucleoli
Cytosol Expressed in all cerebral cortex: 79.1 -COX5B ENSG00000135940 Cytochrome c oxidase subunit Vb 2 97646040-97648383 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034517 Supported Validated Mitochondria Expressed in all skeletal muscle: 447.8 -REV1 REV1L ENSG00000135945 REV1, polymerase (DNA directed) 2 99400475-99490035 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044534, HPA051036 Uncertain Approved Cytosol Expressed in all endometrium: 22.2 -TSGA10 CEP4L, CT79 ENSG00000135951 Testis specific, 10 2 98997261-99154964 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036879, HPA036880 Approved Approved Cytosol Group enriched 11 fallopian tube: 19.0;testis: 92.4 thyroid gland: 4.8 -MFSD9 MGC11332 ENSG00000135953 Major facilitator superfamily domain containing 9 2 102715840-102736888 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055293, HPA061859 Approved Approved Nucleoli Mixed duodenum: 10.1 -TMEM127 FLJ20507, FLJ22257 ENSG00000135956 Transmembrane protein 127 2 96248516-96265994 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 110.4 -EDAR DL, ED1R, ED3, ED5, EDA1R, EDA3, Edar ENSG00000135960 Ectodysplasin A receptor 2 108894471-108989372 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042292 Approved Mixed esophagus: 2.8 -TGFBRAP1 TRAP-1, TRAP1 ENSG00000135966 Transforming growth factor, beta receptor associated protein 1 2 105264391-105330034 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037672, HPA038397 Approved Approved Vesicles Expressed in all parathyroid gland: 20.5 -GCC2 GCC185, KIAA0336 ENSG00000135968 GRIP and coiled-coil domain containing 2 2 108448561-108509415 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035849, HPA035850 Approved Validated Nucleoplasm
Golgi apparatus Mixed epididymis: 33.5 -MRPS9 MRP-S9, RPMS9, S9mt ENSG00000135972 Mitochondrial ribosomal protein S9 2 105037983-105099960 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043476, HPA048479 Supported Validated Nucleoli
Mitochondria Expressed in all testis: 57.6 -GPR45 PSP24, PSP24A ENSG00000135973 G protein-coupled receptor 45 2 105241743-105243049 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055940 Uncertain Tissue enhanced 0 cerebral cortex: 1.8 testis: 0.5 -C2orf49 asw, MGC5509 ENSG00000135974 Chromosome 2 open reading frame 49 2 105337359-105349211 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043846, HPA060814 Approved Supported Nucleoplasm
Mitochondria Expressed in all ovary: 24.2 -ANKRD36 UNQ2430 ENSG00000135976 Ankyrin repeat domain 36 2 97113496-97264521 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA051757, HPA057661 Approved Nucleus
Cytosol Mixed testis: 12.7 -EPC2 DKFZP566F2124 ENSG00000135999 Enhancer of polycomb homolog 2 (Drosophila) 2 148644440-148787568 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036759 Uncertain Approved Nuclear speckles Expressed in all endometrium: 44.0 -ARHGEF4 ASEF, KIAA1112, STM6 ENSG00000136002 Rho guanine nucleotide exchange factor (GEF) 4 2 130836916-131047263 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018267 Approved Tissue enhanced 0 cerebral cortex: 96.7;skin: 57.2 esophagus: 25.4 -ISCU hnifU, IscU, ISU2, NIFUN ENSG00000136003 Iron-sulfur cluster assembly enzyme 12 108562582-108569384 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006329, HPA038602, HPA057592 Approved Supported Cytosol Expressed in all adrenal gland: 401.0 -ALDH1L2 FLJ38508, mtFDH ENSG00000136010 Aldehyde dehydrogenase 1 family, member L2 12 105019784-105084577 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039481 Uncertain Supported Mitochondria Mixed cervix: 8.3 -STAB2 DKFZP434E0321, FEEL-2, FELL, HARE, STAB-2 ENSG00000136011 Stabilin 2 12 103587273-103766727 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026871 Supported Uncertain Cytosol Tissue enriched 6 spleen: 49.0 liver: 7.9 -USP44 FLJ14528 ENSG00000136014 Ubiquitin specific peptidase 44 12 95516560-95551490 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026543 Approved Nucleoli fibrillar center
Microtubules Tissue enriched 7 testis: 43.4 parathyroid gland: 5.9 -SCYL2 CVAK104, KIAA1360 ENSG00000136021 SCY1-like, kinase-like 2 12 100267140-100341724 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021050 Approved Expressed in all parathyroid gland: 41.1 -CKAP4 CLIMP-63, ERGIC-63, P63 ENSG00000136026 Cytoskeleton-associated protein 4 12 106237877-106304279 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000278, HPA000792, HPA001225 Supported Uncertain Nuclear speckles
Cytosol
Cytoplasmic bodies Expressed in all cervix: 78.2 -PLXNC1 CD232, VESPR ENSG00000136040 Plexin C1 12 94148723-94307675 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB026155, HPA066899 Uncertain Approved Mitochondria Mixed appendix: 29.0 -APPL2 DIP13B, FLJ10659 ENSG00000136044 Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 12 105173296-105236238 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039688, HPA043925 Approved Expressed in all skin: 78.1 -PWP1 IEF-SSP-9502 ENSG00000136045 PWP1 homolog, endonuclein 12 107685732-107713167 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038708 Approved Nucleoli
Golgi apparatus Expressed in all testis: 55.1 -DRAM1 DRAM, FLJ11259 ENSG00000136048 DNA-damage regulated autophagy modulator 1 12 101877351-102012130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all lung: 133.6 -KIAA1033 SWIP ENSG00000136051 KIAA1033 12 105107324-105169134 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045666, HPA046737 Uncertain Validated Nucleoplasm Expressed in all lymph node: 51.8 -SLC41A2 DKFZP434K0427 ENSG00000136052 Solute carrier family 41 (magnesium transporter), member 2 12 104802553-104958744 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA038658 Approved Mixed liver: 59.8 -VILL ENSG00000136059 Villin-like 3 37988059-38007188 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035675 Supported Tissue enhanced 0 stomach: 94.8 small intestine: 69.1 -FLNB ABP-278, FH1, FLN1L, LRS1, TABP, TAP ENSG00000136068 Filamin B, beta 3 58008400-58172251 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004747, HPA004886, CAB019322 Supported Supported Golgi apparatus
Plasma membrane
Actin filaments
Cytosol Expressed in all prostate: 161.4 -NEK3 HSPK36, MGC29949 ENSG00000136098 NIMA-related kinase 3 13 52132639-52159861 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019062, HPA043230 Supported Approved Microtubules Expressed in all testis: 29.5 -PCDH8 ARCADLIN, PAPC ENSG00000136099 Protocadherin 8 13 52842889-52848641 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA010509 Uncertain Tissue enriched 8 cerebral cortex: 5.7 testis: 0.7 -VPS36 C13orf9, CGI-145, Eap45 ENSG00000136100 Vacuolar protein sorting 36 homolog (S. cerevisiae) 13 52412602-52450628 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039734, HPA043947 Approved Supported Vesicles
Lysosomes
Plasma membrane
Cell Junctions Expressed in all skin: 62.6 -RNASEH2B AGS2, DLEU8, FLJ11712 ENSG00000136104 Ribonuclease H2, subunit B 13 50909678-50973745 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040084, HPA041469 Approved Validated Nucleus Expressed in all lymph node: 27.4 -CKAP2 FLJ10749, LB1, se20-10, TMAP ENSG00000136108 Cytoskeleton associated protein 2 13 52455429-52476628 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008410, HPA027821 Approved Validated Microtubules
Cytosol Tissue enhanced 0 testis: 58.6 bone marrow: 42.5 -LECT1 BRICD3, CHM-I, CHM1, chondromodulin, MYETS1 ENSG00000136110 Leukocyte cell derived chemotaxin 1 13 52703264-52739812 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010510 Uncertain Tissue enhanced 0 salivary gland: 3.1;testis: 3.5;thyroid gland: 5.8 lung: 2.5 -TBC1D4 AS160, DKFZp779C0666, KIAA0603 ENSG00000136111 TBC1 domain family, member 4 13 75284665-75482114 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040145, HPA059885 Approved Supported Cytosol Expressed in all adrenal gland: 83.2 -THSD1 TMTSP ENSG00000136114 Thrombospondin, type I, domain containing 1 13 52377167-52406494 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA012611, CAB020796 Uncertain Validated Cytosol Mixed lung: 16.6 -BORA C13orf34, FLJ22624 ENSG00000136122 Bora, aurora kinase A activator 13 72727749-72756198 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040866 Approved Approved Nucleus
Nucleoli Mixed lymph node: 10.6 -LRCH1 CHDC1, KIAA1016 ENSG00000136141 Leucine-rich repeats and calponin homology (CH) domain containing 1 13 46553168-46753040 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021536 Uncertain Approved Nucleoli
Actin filaments
Cytosol Expressed in all endometrium: 26.6 -SUCLA2 ENSG00000136143 Succinate-CoA ligase, ADP-forming, beta subunit 13 47936491-48001354 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039435, HPA039536, HPA061528 Supported Supported Validated Mitochondria Expressed in all skeletal muscle: 78.8 -RCBTB1 CLLD7, CLLL7, FLJ10716 ENSG00000136144 Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 13 49531946-49585583 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA056783 Approved Nucleoplasm Expressed in all thyroid gland: 73.7 -MED4 DRIP36, HSPC126, TRAP36, VDRIP ENSG00000136146 Mediator complex subunit 4 13 48053323-48095131 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006232 Approved Supported Nucleoplasm Expressed in all testis: 102.8 -PHF11 BCAP, IGER, NY-REN-34 ENSG00000136147 PHD finger protein 11 13 49495610-49528987 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016566, HPA016708 Uncertain Supported Nucleoplasm
Nuclear membrane Expressed in all thyroid gland: 57.4 -COG3 SEC34 ENSG00000136152 Component of oligomeric golgi complex 3 13 45464898-45536630 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040353 Approved Expressed in all prostate: 29.8 -LMO7 FBX20, FBXO20, KIAA0858 ENSG00000136153 LIM domain 7 13 75620434-75859870 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020923, HPA050184 Approved Supported Actin filaments
Cytosol Expressed in all lung: 269.8 -SCEL FLJ21667, MGC22531 ENSG00000136155 Sciellin 13 77535674-77645263 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039737, HPA040154 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 esophagus: 478.3;skin: 397.8 lung: 99.0 -ITM2B BRI, BRI2, BRICD2B, E25B, E3-16 ENSG00000136156 Integral membrane protein 2B 13 48233158-48270357 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029292, HPA071992 Approved Validated Golgi apparatus
Vesicles Expressed in all epididymis: 1826.9 -SPRY2 hSPRY2 ENSG00000136158 Sprouty RTK signaling antagonist 2 13 80335976-80340951 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037205, HPA042198 Approved Supported Microtubules Expressed in all adipose tissue: 69.8 -NUDT15 FLJ10956, MTH2 ENSG00000136159 Nudix (nucleoside diphosphate linked moiety X)-type motif 15 13 48037567-48047222 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038968, HPA038969 Approved Supported Nucleoplasm Expressed in all prostate: 23.9 -EDNRB ETB, HSCR, HSCR2 ENSG00000136160 Endothelin receptor type B 13 77895481-77919768 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017842, HPA027546 Approved Approved Plasma membrane
Cytosol Tissue enhanced 0 placenta: 178.8 cerebral cortex: 89.1 -RCBTB2 CHC1L ENSG00000136161 Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 13 48488959-48533256 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040242 Approved Approved Nucleus
Golgi apparatus Expressed in all thyroid gland: 44.8 -LCP1 CP64, L-PLASTIN, LC64P, PLS2 ENSG00000136167 Lymphocyte cytosolic protein 1 (L-plastin) 13 46125920-46211871 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019493, CAB020673 Supported Approved Plasma membrane
Actin filaments
Cytosol Expressed in all lymph node: 622.1 -SETDB2 C13orf4, CLLD8, CLLL8, KMT1F ENSG00000136169 SET domain, bifurcated 2 13 49444374-49495003 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB012190, HPA071677 Approved Approved Nucleoplasm Mixed testis: 28.1 -SCRN1 KIAA0193 ENSG00000136193 Secernin 1 7 29920103-29990289 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024517 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 172.5 parathyroid gland: 126.6 -C7orf25 MGC2821 ENSG00000136197 Chromosome 7 open reading frame 25 7 42908726-42912305 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020120, HPA049635 Approved Supported Nucleoplasm
Cytosol Mixed testis: 7.9 -TNS3 FLJ13732, H_NH0549I23.2, TEM6, TENS1 ENSG00000136205 Tensin 3 7 47275154-47582558 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055338, HPA056015 Approved Validated Focal adhesion sites Expressed in all placenta: 80.9 -SPDYE1 Ringo1, SPDYE, WBSCR19 ENSG00000136206 Speedy/RINGO cell cycle regulator family member E1 7 44000889-44010122 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044799, HPA051750 Uncertain Tissue enriched 6 testis: 8.2 skin: 1.2 -CHST12 C4S-2, C4ST2 ENSG00000136213 Carbohydrate (chondroitin 4) sulfotransferase 12 7 2403560-2448483 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041680 Approved Approved Golgi apparatus Expressed in all spleen: 16.4 -IGF2BP3 CT98, IMP-3, IMP3 ENSG00000136231 Insulin-like growth factor 2 mRNA binding protein 3 7 23310209-23470467 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002037 Approved Validated Cytosol Tissue enhanced 0 placenta: 40.3 testis: 8.9 -GPNMB HGFIN, NMB ENSG00000136235 Glycoprotein (transmembrane) nmb 7 23235967-23275108 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all skin: 656.2 -RAPGEF5 GFR, KIAA0277, MR-GEF ENSG00000136237 Rap guanine nucleotide exchange factor (GEF) 5 7 22118238-22357144 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057821, HPA076772 Uncertain Supported Nucleoplasm
Nuclear bodies Tissue enriched 12 parathyroid gland: 1182.1 placenta: 96.1 -RAC1 p21-Rac1, Rac-1, TC-25 ENSG00000136238 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 7 6374523-6403977 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB035994, HPA047820 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all cerebral cortex: 282.4 -KDELR2 ELP-1, ERD2.2 ENSG00000136240 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 7 6445953-6484242 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016459 Approved Expressed in all placenta: 202.3 -NUPL2 CG1, hCG1, H_RG271G13.9, NLP_1 ENSG00000136243 Nucleoporin like 2 7 23181827-23201011 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049036, HPA057251 Validated Nucleus Expressed in all testis: 32.6 -IL6 BSF2, HGF, HSF, IFNB2, IL-6 ENSG00000136244 Interleukin 6 7 22725884-22732002 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB023406, CAB072821 Supported Approved Vesicles Tissue enhanced 0 adipose tissue: 135.4 urinary bladder: 76.8 -ZDHHC4 FLJ10479, ZNF374 ENSG00000136247 Zinc finger, DHHC-type containing 4 7 6577434-6589374 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA032124, HPA064358 Approved Approved Nuclear bodies Expressed in all thyroid gland: 77.5 -AOAH ENSG00000136250 Acyloxyacyl hydrolase (neutrophil) 7 36512949-36724549 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021666, HPA026716 Uncertain Tissue enhanced 0 spleen: 90.2 appendix: 47.2 -BZW2 HSPC028, MST017, MSTP017 ENSG00000136261 Basic leucine zipper and W2 domains 2 7 16646131-16706523 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022813, HPA026709 Approved Approved Plasma membrane
Actin filaments
Cytosol Expressed in all heart muscle: 167.1 -DGKB DAGK2, DGK, DGK-BETA, KIAA0718 ENSG00000136267 Diacylglycerol kinase, beta 90kDa 7 14145049-14974777 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA020321 Supported Tissue enriched 6 cerebral cortex: 34.3 endometrium: 5.6 -TBRG4 Cpr2, FASTKD4, H_TD2522F11.8, KIAA0948 ENSG00000136270 Transforming growth factor beta regulator 4 7 45100100-45112047 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020582, HPA050430 Approved Validated Mitochondria Expressed in all testis: 41.8 -DDX56 NOH61 ENSG00000136271 DEAD (Asp-Glu-Ala-Asp) box helicase 56 7 44565417-44575051 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019749 Uncertain Expressed in all skin: 5.6 -HUS1 ENSG00000136273 HUS1 checkpoint clamp component 7 47695730-47979581 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026787 Approved Mixed parathyroid gland: 11.9 -NACAD KIAA0363 ENSG00000136274 NAC alpha domain containing 7 45080438-45088914 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020981 Approved Approved Nucleus
Cytosol Tissue enriched 6 cerebral cortex: 48.9 ovary: 7.6 -DBNL HIP-55, SH3P7 ENSG00000136279 Drebrin-like 7 44044640-44069456 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020265, HPA027735 Supported Supported Nucleoplasm
Cytosol Expressed in all esophagus: 142.5 -CCM2 C7orf22, MGC4607, OSM ENSG00000136280 Cerebral cavernous malformation 2 7 44999475-45076469 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020273, HPA021669, HPA065815 Supported Validated Mitochondria Expressed in all lymph node: 49.8 -MYO1G HA-2 ENSG00000136286 Myosin IG 7 44962662-44979098 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021252 Supported Tissue enhanced 0 bone marrow: 27.8;lymph node: 28.0;spleen: 25.1 appendix: 22.6 -TTYH3 KIAA1691 ENSG00000136295 Tweety family member 3 7 2631951-2664802 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053520 Uncertain Expressed in all cerebral cortex: 62.4 -MMD2 PAQR10 ENSG00000136297 Monocyte to macrophage differentiation-associated 2 7 4905989-4959213 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 82 cerebral cortex: 41.3;testis: 12.4 adrenal gland: 0.3 -CIDEB ENSG00000136305 Cell death-inducing DFFA-like effector b 14 24305096-24311430 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001272 Uncertain Expressed in all liver: 182.8 -TTC5 Strap ENSG00000136319 Tetratricopeptide repeat domain 5 14 20256558-20305994 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045008, HPA054198 Approved Supported Nucleoplasm Mixed parathyroid gland: 10.4 -NKX2-8 Nkx2-9, NKX2.8, NKX2H ENSG00000136327 NK2 homeobox 8 14 36580579-36582607 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062879 Uncertain Approved Nucleoplasm
Plasma membrane Tissue enhanced 0 testis: 3.1 lung: 0.6 -NKX2-1 BCH, NKX2A, TITF1, TTF-1, TTF1 ENSG00000136352 NK2 homeobox 1 14 36516392-36521149 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000078, CAB053633, HPA074316 Supported Uncertain Golgi apparatus
Vesicles Group enriched 174 lung: 102.0;thyroid gland: 103.6 stomach: 0.5 -ZFHX2 KIAA1056, KIAA1762, ZFH-5, ZNF409 ENSG00000136367 Zinc finger homeobox 2 14 23520855-23556192 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000720, HPA005146 Uncertain Approved Nucleus
Nucleoli fibrillar center Tissue enhanced 0 testis: 13.1 parathyroid gland: 4.0 -MTHFS HsT19268 ENSG00000136371 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 15 79833585-79897379 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008067, HPA054177 Approved Supported Cytosol Expressed in all liver: 115.9 -ADAMTS7 ADAM-TS7, DKFZp434H204 ENSG00000136378 ADAM metallopeptidase with thrombospondin type 1 motif, 7 15 78759203-78811431 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045284, HPA048453 Uncertain Approved Vesicles Tissue enhanced 0 endometrium: 7.2 heart muscle: 4.7 -ABHD17C FAM108C1 ENSG00000136379 Abhydrolase domain containing 17C 15 80679684-80755621 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048890 Uncertain Mixed colon: 65.2 -IREB2 IRP2 ENSG00000136381 Iron-responsive element binding protein 2 15 78437431-78501456 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB032885, HPA040371, HPA068982 Uncertain Approved Cell Junctions
Cytosol Expressed in all thyroid gland: 47.9 -ALPK3 KIAA1330, MAK, Midori ENSG00000136383 Alpha-kinase 3 15 84816680-84873482 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026558 Uncertain Approved Nucleus Tissue enhanced 0 heart muscle: 32.4;parathyroid gland: 35.6;skeletal muscle: 47.6 adipose tissue: 12.3 -TM6SF1 ENSG00000136404 Transmembrane 6 superfamily member 1 15 83107407-83144854 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016051, HPA056857 Uncertain Approved Intermediate filaments Mixed thyroid gland: 13.2 -CIB2 DFNB48, KIP2, USH1J ENSG00000136425 Calcium and integrin binding family member 2 15 78104606-78131544 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036697 Approved Mixed testis: 31.5 -CALCOCO2 MGC17318, NDP52 ENSG00000136436 Calcium binding and coiled-coil domain 2 17 48830988-48866522 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022989, HPA023019, HPA023195 Supported Supported Vesicles
Cytosol Expressed in all testis: 247.8 -RSAD1 FLJ11164 ENSG00000136444 Radical S-adenosyl methionine domain containing 1 17 50478800-50485975 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA022436, HPA022967 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 36.0 -NMT1 NMT ENSG00000136448 N-myristoyltransferase 1 17 45051610-45109016 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022949, HPA022963 Supported Supported Plasma membrane
Cytosol Expressed in all cerebral cortex: 58.8 -MYCBPAP AMAP-1, DKFZp434N1415 ENSG00000136449 MYCBP associated protein 17 50508384-50531501 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023257, HPA024405 Supported Approved Vesicles Tissue enriched 12 testis: 91.0 fallopian tube: 7.6 -SRSF1 ASF, MGC5228, SF2, SF2p33, SFRS1, SRp30a ENSG00000136450 Serine/arginine-rich splicing factor 1 17 58003360-58007346 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013073, HPA061301 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 153.4 -VEZF1 DB1, ZNF161 ENSG00000136451 Vascular endothelial zinc finger 1 17 57971547-57988259 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027520, HPA048315 Uncertain Validated Nucleoplasm Expressed in all thyroid gland: 81.7 -CHAD SLRR4A ENSG00000136457 Chondroadherin 17 50464496-50468966 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA018241 Supported Tissue enhanced 0 cervix, uterine: 33.1 breast: 14.0 -TACO1 CCDC44 ENSG00000136463 Translational activator of mitochondrially encoded cytochrome c oxidase I 17 63600872-63608365 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021626, HPA021643, HPA024294 Supported Validated Mitochondria Expressed in all kidney: 30.5 -TEX2 HT008, KIAA1738, TMEM96 ENSG00000136478 Testis expressed 2 17 64147227-64263301 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020648, HPA057116 Approved Approved Nucleus Expressed in all testis: 99.2 -DCAF7 HAN11, SWAN-1, WDR68 ENSG00000136485 DDB1 and CUL4 associated factor 7 17 63550461-63594266 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022948, HPA022962 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 60.3 -GH2 GH-V , GH2, GHL, GHV, hGH-V ENSG00000136487 Growth hormone 2 17 63880215-63881935 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043715 Supported Tissue enriched 202 placenta: 189.0 smooth muscle: 0.9 -CSH1 CSA, CSMT, FLJ75407, hCS-A, PL ENSG00000136488 Chorionic somatomammotropin hormone 1 (placental lactogen) 17 63894909-63896661 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026374, HPA043715 Supported Tissue enriched 214 placenta: 13476.0 smooth muscle: 63.0 -LIMD2 MGC10986 ENSG00000136490 LIM domain containing 2 17 63695902-63701172 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062867 Approved Vesicles Group enriched 5 appendix: 145.1;bone marrow: 71.3;lymph node: 259.7;spleen: 195.3;tonsil: 145.7 urinary bladder: 31.4 -BRIP1 BACH1, FANCJ, OF ENSG00000136492 BRCA1 interacting protein C-terminal helicase 1 17 61681266-61863521 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005474 Approved Supported Nucleus
Nuclear membrane Tissue enhanced 0 testis: 14.4 bone marrow: 5.0 -KAT7 HBO1, HBOA, MYST2, ZC2HC7 ENSG00000136504 K(lysine) acetyltransferase 7 17 49788555-49835030 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044470 Approved Supported Nucleoplasm Expressed in all testis: 106.4 -RTP4 IFRG28, Z3CXXC4 ENSG00000136514 Receptor (chemosensory) transporter protein 4 3 187368332-187372076 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA064887, HPA071189 Uncertain Supported Nucleus Mixed fallopian tube: 16.5 -ACTL6A Actl6, Arp4, BAF53A, INO80K ENSG00000136518 Actin-like 6A 3 179562880-179588408 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012188, HPA018671 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 111.9 -NDUFB5 CI-SGDH, MGC12314, SGDH ENSG00000136521 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 3 179604690-179627647 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005640 Supported Supported Nucleoplasm
Mitochondria Expressed in all heart muscle: 133.4 -MRPL47 CGI-204, NCM1 ENSG00000136522 Mitochondrial ribosomal protein L47 3 179588285-179604654 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037553, HPA047779 Approved Validated Mitochondria Expressed in all testis: 84.5 -TRA2B Htra2-beta, PPP1R156, SFRS10 ENSG00000136527 Transformer 2 beta homolog (Drosophila) 3 185915906-185938136 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011692, HPA063597, HPA064972 Supported Validated Nucleoplasm Expressed in all appendix: 58.5 -SCN2A HBSCI, HBSCII, Nav1.2, SCN2A1, SCN2A2 ENSG00000136531 Sodium channel, voltage gated, type II alpha subunit 2 165239402-165392310 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022567 Supported Tissue enriched 22 cerebral cortex: 58.5 kidney: 2.7 -TBR1 ENSG00000136535 T-box, brain, 1 2 161416094-161425870 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051256 Approved Tissue enriched 29 cerebral cortex: 30.7 testis: 1.0 -MARCH7 AXOT, MARCH-VII, RNF177 ENSG00000136536 Membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 2 159712457-159771027 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014275, HPA022152 Approved Supported Plasma membrane
Cytosol Expressed in all testis: 111.7 -ERMN ERMIN, JN, KIAA1189 ENSG00000136541 Ermin, ERM-like protein 2 157318625-157327713 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038295, HPA038296 Supported Tissue enriched 27 cerebral cortex: 228.3 bone marrow: 8.4 -GALNT5 GalNAc-T5 ENSG00000136542 Polypeptide N-acetylgalactosaminyltransferase 5 2 157257598-157314211 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008963, HPA009035 Approved Approved Nucleoli
Golgi apparatus
Vesicles
Cytosol Tissue enhanced 0 lung: 18.4;rectum: 20.1;stomach: 16.9 colon: 14.2 -SCN7A NaG, Nav2.1, Nav2.2, SCN6A ENSG00000136546 Sodium channel, voltage gated, type VII alpha subunit 2 166403573-166494247 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004879 Uncertain Tissue enhanced 0 ovary: 63.0 lung: 41.0 -TANK I-TRAF, TRAF2 ENSG00000136560 TRAF family member-associated NFKB activator 2 161136908-161236221 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010345, HPA037675, HPA037676 Approved Supported Nucleoli
Cytosol Expressed in all breast: 67.9 -BLK MGC10442 ENSG00000136573 BLK proto-oncogene, Src family tyrosine kinase 8 11494001-11564604 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005093 Approved Group enriched 10 appendix: 22.9;lymph node: 61.9;spleen: 41.3;tonsil: 54.0 urinary bladder: 4.5 -GATA4 ENSG00000136574 GATA binding protein 4 8 11676959-11760002 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013125, HPA073899 Uncertain Supported Nuclear bodies Tissue enhanced 0 duodenum: 74.5;heart muscle: 61.7;ovary: 111.8 testis: 51.4 -SKIL SNO, SnoA, SnoN ENSG00000136603 SKI-like proto-oncogene 3 170357678-170396835 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008472 Uncertain Approved Nucleoplasm
Cytosol Expressed in all gallbladder: 37.0 -EPRS EARS, GLUPRORS, PARS, QARS, QPRS ENSG00000136628 Glutamyl-prolyl-tRNA synthetase 1 219968601-220046658 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026490, HPA030052 Supported Validated Cytosol Expressed in all parathyroid gland: 118.2 -HLX HB24, HLX1 ENSG00000136630 H2.0-like homeobox 1 220879400-220885059 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA005968 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 bone marrow: 60.5 lung: 27.2 -VPS45 h-vps45, H1, VPS45A, VPS45B ENSG00000136631 Vacuolar protein sorting 45 homolog (S. cerevisiae) 1 150067293-150145327 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027425, HPA027441 Uncertain Approved Microtubules Expressed in all cerebral cortex: 37.7 -IL10 CSIF, IL-10, IL10A, TGIF ENSG00000136634 Interleukin 10 1 206767602-206772494 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013120 Approved Tissue enhanced 0 appendix: 8.9 adipose tissue: 7.4 -KCTD3 NY-REN-45 ENSG00000136636 Potassium channel tetramerization domain containing 3 1 215567392-215621807 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015142 Approved Approved Cytosol Expressed in all adrenal gland: 104.2 -RPS6KC1 humS6PKh1 ENSG00000136643 Ribosomal protein S6 kinase, 52kDa, polypeptide 1 1 213051233-213274773 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026531, HPA031565 Approved Validated Endosomes
Lysosomes
Cytosol Expressed in all testis: 35.2 -CBWD2 ENSG00000136682 COBW domain containing 2 2 113437691-113496189 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042759, HPA042813 Approved Approved Plasma membrane Mixed parathyroid gland: 18.6 -IL36G IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1 ENSG00000136688 Interleukin 36, gamma 2 112973203-112985665 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 10 skin: 15.8;tonsil: 40.8 esophagus: 2.7 -IL1RN ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430 ENSG00000136689 Interleukin 1 receptor antagonist 2 113107214-113134016 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001482, CAB009633 Supported Tissue enhanced 0 esophagus: 1248.5 tonsil: 301.6 -IL36A FIL1, FIL1E, IL-1F6, IL1(EPSILON), IL1F6, MGC129552, MGC129553 ENSG00000136694 Interleukin 36, alpha 2 113005461-113008044 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 1269 esophagus: 463.3;tonsil: 110.1 endometrium: 0.2 -IL36RN FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840 ENSG00000136695 Interleukin 36 receptor antagonist 2 113058638-113065382 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA034542 Uncertain Group enriched 7 esophagus: 17.2;skin: 40.8;tonsil: 39.6 placenta: 4.7 -IL36B FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882 ENSG00000136696 Interleukin 36, beta 2 113022091-113052867 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035664 Uncertain Tissue enhanced 0 esophagus: 2.2;skin: 7.4;tonsil: 3.5 breast: 1.2 -IL1F10 FKSG75, IL-1F10, IL-1HY2, IL1-theta, MGC11983, MGC119832, MGC119833 ENSG00000136697 Interleukin 1 family, member 10 (theta) 2 113067970-113075850 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059813 Approved Group enriched 5 skin: 4.8;tonsil: 2.6 breast: 0.6 -CFC1 CRYPTIC, HTX2 ENSG00000136698 Cripto, FRL-1, cryptic family 1 2 130592168-130599575 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041773 Uncertain Tissue enhanced 0 pancreas: 4.1;prostate: 9.0;stomach: 7.9 fallopian tube: 1.7 -SMPD4 FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3 ENSG00000136699 Sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 2 130151392-130182750 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046279, HPA049426 Approved Approved Nuclear membrane
Cytosol Expressed in all testis: 36.3 -WDR33 FLJ11294, NET14, WDC146 ENSG00000136709 WD repeat domain 33 2 127701022-127811187 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026897, HPA046527 Supported Supported Nucleoplasm
Nucleoli fibrillar center Expressed in all testis: 38.5 -CCDC115 ccp1, FLJ30131, MGC12981 ENSG00000136710 Coiled-coil domain containing 115 2 130338241-130342349 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034598 Approved Supported Vesicles
Plasma membrane Expressed in all ovary: 55.3 -SAP130 FLJ12761 ENSG00000136715 Sin3A-associated protein, 130kDa 2 127941217-128028120 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034664 Supported Nuclear speckles Expressed in all testis: 86.7 -BIN1 AMPH2, AMPHL, SH3P9 ENSG00000136717 Bridging integrator 1 2 127048027-127107355 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001945, HPA003894, HPA005437 Supported Supported Cytosol Group enriched 7 cerebral cortex: 156.9;skeletal muscle: 724.3 adrenal gland: 61.7 -IMP4 BXDC4, MGC19606 ENSG00000136718 IMP4, U3 small nucleolar ribonucleoprotein 2 130342225-130347810 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066222, HPA066673 Validated Nucleoli Mixed lymph node: 23.1 -HS6ST1 HS6ST ENSG00000136720 Heparan sulfate 6-O-sulfotransferase 1 2 128236716-128318577 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044586 Approved Nucleoplasm Expressed in all cerebral cortex: 40.9 -UGGT1 HUGT1, UGCGL1 ENSG00000136731 UDP-glucose glycoprotein glucosyltransferase 1 2 128091200-128195677 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012761, HPA015127 Supported Uncertain Cytosol Expressed in all epididymis: 23.8 -GYPC CD236, CD236R, Ge, GPC, GYPD ENSG00000136732 Glycophorin C (Gerbich blood group) 2 126655933-126696675 Blood group antigen proteins, CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008965, CAB009445 Supported Approved Vesicles
Cytosol Expressed in all bone marrow: 230.3 -STAM STAM1 ENSG00000136738 Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 10 17644125-17715914 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034399, HPA043882 Supported Supported Vesicles Expressed in all bone marrow: 41.9 -GAD2 GAD65 ENSG00000136750 Glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 10 26216307-26304558 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044637, CAB078177 Supported Tissue enriched 17 cerebral cortex: 23.0 pancreas: 1.3 -ABI1 ABI-1, E3B1, SSH3BP1 ENSG00000136754 Abl-interactor 1 10 26746593-26861087 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008375, HPA029973, HPA068407 Approved Supported Plasma membrane
Cell Junctions Expressed in all cerebral cortex: 87.6 -YME1L1 ENSG00000136758 YME1-like 1 ATPase 10 27110112-27155266 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066953 Approved Supported Nuclear bodies
Mitochondria Expressed in all thyroid gland: 105.3 -DNAJC1 DNAJL1, ERdj1, MTJ1 ENSG00000136770 DnaJ (Hsp40) homolog, subfamily C, member 1 10 21756537-22003769 Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013432 Approved Approved Endoplasmic reticulum Expressed in all parathyroid gland: 56.8 -NIPSNAP3A DKFZp564D177, FLJ13953, HSPC299, MGC14553 ENSG00000136783 Nipsnap homolog 3A (C. elegans) 9 104747688-104760122 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042491 Approved Expressed in all adrenal gland: 51.1 -LRRC8A FLJ10337, KIAA1437, LRRC8, SWELL1 ENSG00000136802 Leucine rich repeat containing 8 family, member A 9 128882112-128918039 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 89.9 -CDK9 C-2k, CDC2L4, PITALRE, TAK ENSG00000136807 Cyclin-dependent kinase 9 9 127785679-127790787 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004216, HPA006738 Supported Approved Nucleoplasm
Cytoplasmic bodies Expressed in all ovary: 60.3 -TXN TRX ENSG00000136810 Thioredoxin 9 110243811-110256640 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008678, HPA047478, HPA055752 Supported Validated Nucleus
Nucleoli
Cytosol Expressed in all esophagus: 705.8 -ODF2 CT134, ODF84 ENSG00000136811 Outer dense fiber of sperm tails 2 9 128455186-128501292 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001874, HPA048841 Supported Supported Centrosome Tissue enriched 15 testis: 533.7 fallopian tube: 36.2 -KIAA0368 ECM29, FLJ22036 ENSG00000136813 KIAA0368 9 111360692-111484745 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021646, HPA059795 Uncertain Supported Nucleus Expressed in all parathyroid gland: 79.3 -TOR1B DQ1, MGC4386 ENSG00000136816 Torsin family 1, member B (torsin B) 9 129803153-129811281 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013403, HPA013697, CAB022709 Approved Approved Nuclear speckles
Cytosol Expressed in all rectum: 25.2 -C9orf78 HCA59, HSPC220 ENSG00000136819 Chromosome 9 open reading frame 78 9 129827290-129835863 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021216, HPA021232, HPA021242 Supported Validated Nucleoplasm Expressed in all bone marrow: 71.4 -SMC2 CAP-E, hCAP-E, SMC2L1 ENSG00000136824 Structural maintenance of chromosomes 2 9 104094260-104141417 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071309 Approved Supported Nucleus
Nucleoli Mixed testis: 22.1 -KLF4 EZF, GKLF ENSG00000136826 Kruppel-like factor 4 (gut) 9 107484852-107490482 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002926 Supported Supported Nucleoplasm Expressed in all esophagus: 129.0 -TOR1A DQ2, DYT1 ENSG00000136827 Torsin family 1, member A (torsin A) 9 129812944-129824134 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012473, HPA051195 Approved Supported Nuclear membrane
Vesicles Expressed in all thyroid gland: 39.8 -RALGPS1 KIAA0351, RALGEF2, RALGPS1A ENSG00000136828 Ral GEF with PH domain and SH3 binding motif 1 9 126914774-127223166 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all small intestine: 32.7 -FAM129B bA356B19.6, C9orf88, DKFZP434H0820, FLJ13518, FLJ22151, FLJ22298, MINERVA ENSG00000136830 Family with sequence similarity 129, member B 9 127505339-127578989 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021284, HPA021417, HPA023261, HPA024312 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all esophagus: 363.7 -OR1J1 hg32 ENSG00000136834 Olfactory receptor, family 1, subfamily J, member 1 9 122476958-122477926 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.2 -OR13C9 ENSG00000136839 Olfactory receptor, family 13, subfamily C, member 9 9 104617248-104618204 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -ST6GALNAC4 SIAT3C, SIAT7D, ST6GALNACIV ENSG00000136840 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 9 127907886-127917038 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA009042 Approved Nucleus
Golgi apparatus Mixed bone marrow: 24.5 -TMOD1 D9S57E, ETMOD, TMOD ENSG00000136842 Tropomodulin 1 9 97501180-97601748 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051202 Supported Approved Cytosol Mixed heart muscle: 97.8 -DAB2IP AF9Q34, AIP1, DIP1/2, KIAA1743 ENSG00000136848 DAB2 interacting protein 9 121567057-121785530 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed testis: 33.9 -STXBP1 hUNC18, MUNC18-1, rbSec1, UNC18 ENSG00000136854 Syntaxin binding protein 1 9 127611760-127692936 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008209, HPA023483, CAB034434 Supported Approved Nucleoplasm
Cytosol Tissue enriched 8 cerebral cortex: 401.8 fallopian tube: 51.7 -SLC2A8 GLUT8, GLUTX1 ENSG00000136856 Solute carrier family 2 (facilitated glucose transporter), member 8 9 127397138-127408424 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011935 Uncertain Approved Vesicles Expressed in all testis: 50.1 -ANGPTL2 ARP2, HARP ENSG00000136859 Angiopoietin-like 2 9 127087332-127122883 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040933, HPA041299 Approved Mixed adipose tissue: 114.6 -CDK5RAP2 C48, CEP215, FLJ10867, MCPH3 ENSG00000136861 CDK5 regulatory subunit associated protein 2 9 120388869-120580170 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035820, HPA046529 Approved Validated Cell Junctions
Centrosome Expressed in all testis: 37.2 -ZFP37 ZNF906 ENSG00000136866 ZFP37 zinc finger protein 9 113038380-113056759 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049112 Uncertain Approved Nucleus
Vesicles Mixed ovary: 8.8 -SLC31A2 COPT2, CTR2, hCTR2 ENSG00000136867 Solute carrier family 31 (copper transporter), member 2 9 113150942-113164137 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA014861 Approved Approved Nuclear speckles
Plasma membrane
Intermediate filaments Expressed in all salivary gland: 170.9 -SLC31A1 COPT1, CTR1, hCTR1 ENSG00000136868 Solute carrier family 31 (copper transporter), member 1 9 113221562-113264492 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013810 Approved Expressed in all liver: 56.5 -TLR4 ARMD10, CD284, hToll, TLR-4 ENSG00000136869 Toll-like receptor 4 9 117704332-117716871 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004025, HPA049174 Approved Approved Golgi apparatus
Cytosol Mixed spleen: 49.0 -ZNF189 ENSG00000136870 Zinc finger protein 189 9 101398873-101410660 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA034814 Uncertain Approved Intermediate filaments Expressed in all epididymis: 102.8 -ALDOB ENSG00000136872 Aldolase B, fructose-bisphosphate 9 101420578-101435823 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002198, CAB020827 Supported Group enriched 23 duodenum: 3808.7;kidney: 6531.8;liver: 5081.5;small intestine: 5731.3 gallbladder: 232.6 -STX17 FLJ20651 ENSG00000136874 Syntaxin 17 9 99906633-99970341 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001204 Approved Uncertain Nucleoli
Cytosol Expressed in all parathyroid gland: 36.1 -PRPF4 HPRP4, HPRP4P, PRP4, Prp4p, SNRNP60 ENSG00000136875 Pre-mRNA processing factor 4 9 113275343-113292905 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021794, HPA022248 Supported Validated Nuclear speckles Expressed in all epididymis: 24.0 -FPGS ENSG00000136877 Folylpolyglutamate synthase 9 127794597-127814327 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050488 Approved Expressed in all ovary: 26.1 -USP20 KIAA1003 ENSG00000136878 Ubiquitin specific peptidase 20 9 129834698-129881838 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006287, HPA007008 Uncertain Approved Approved Nucleus
Plasma membrane
Cytosol Expressed in all thyroid gland: 22.1 -BAAT BAT ENSG00000136881 Bile acid CoA:amino acid N-acyltransferase 9 101360417-101383519 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021251, HPA021330 Supported Uncertain Vesicles Tissue enriched 16 liver: 340.0 gallbladder: 21.2 -KIF12 ENSG00000136883 Kinesin family member 12 9 114086126-114099227 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA020192, HPA024127 Uncertain Approved Mitochondria Tissue enhanced 0 gallbladder: 31.6;kidney: 37.9 thyroid gland: 28.6 -ATP6V1G1 ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10 ENSG00000136888 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 9 114587746-114598373 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004615, HPA042898 Supported Supported Nucleus
Nucleoli Expressed in all epididymis: 295.9 -TEX10 bA208F1.2, FLJ20287, Ipi1 ENSG00000136891 Testis expressed 10 9 100302077-100352939 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 41.6 -GARNL3 bA356B19.1, DKFZp761J1523 ENSG00000136895 GTPase activating Rap/RanGAP domain-like 3 9 127224265-127393660 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA022433, HPA028757 Uncertain Approved Vesicles Mixed parathyroid gland: 15.2 -MRPL50 FLJ20493, MRP-L50 ENSG00000136897 Mitochondrial ribosomal protein L50 9 101387633-101398614 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022925 Approved Expressed in all adrenal gland: 20.9 -DPM2 MGC111193, MGC21559 ENSG00000136908 Dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 9 127935099-127938484 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA064623 Approved Mixed stomach: 25.0 -WDR38 ENSG00000136918 WD repeat domain 38 9 124853417-124857890 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056607 Uncertain Tissue enriched 17 fallopian tube: 123.5 lung: 7.3 -TSTD2 C9orf97, PP4189 ENSG00000136925 Thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 9 97600080-97633575 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022537, HPA024241, HPA064304 Uncertain Approved Nucleoplasm Expressed in all parathyroid gland: 15.6 -GABBR2 GABABR2, GPR51, GPRC3B, HG20 ENSG00000136928 Gamma-aminobutyric acid (GABA) B receptor, 2 9 98288082-98709197 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013820, HPA031684 Supported Tissue enriched 19 cerebral cortex: 88.4 adrenal gland: 4.6 -HEMGN CT155, EDAG, NDR ENSG00000136929 Hemogen 9 97926791-97944856 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019572, HPA019604, HPA019606 Supported Group enriched 14 bone marrow: 142.0;testis: 87.7 placenta: 8.1 -PSMB7 ENSG00000136930 Proteasome subunit beta 7 9 124353466-124415444 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052408, HPA054902 Supported Supported Nucleoplasm
Cytosol Expressed in all testis: 236.6 -NR5A1 AD4BP, ELP, FTZ1, FTZF1, SF-1 ENSG00000136931 Nuclear receptor subfamily 5, group A, member 1 9 124481236-124507430 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 adrenal gland: 138.2;ovary: 36.3;spleen: 154.3 testis: 19.6 -TRMO C9orf156, HSPC219 ENSG00000136932 TRNA methyltransferase O 9 97904489-97922570 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021281, HPA052197 Approved Approved Nucleoplasm Expressed in all thyroid gland: 29.5 -RABEPK bA65N13.1, RAB9P40 ENSG00000136933 Rab9 effector protein with kelch motifs 9 125200542-125234158 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023920, HPA067106 Supported Uncertain Plasma membrane Expressed in all liver: 30.6 -GOLGA1 golgin-97, MGC33154 ENSG00000136935 Golgin A1 9 124878357-124948492 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013065, HPA044329, HPA050555 Supported Validated Golgi apparatus Expressed in all testis: 28.7 -XPA XP1, XPAC ENSG00000136936 Xeroderma pigmentosum, complementation group A 9 97674909-97697357 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000155, HPA056856 Supported Approved Nucleus
Cytokinetic bridge Expressed in all thyroid gland: 38.9 -NCBP1 CBP80, NCBP, Sto1 ENSG00000136937 Nuclear cap binding protein subunit 1, 80kDa 9 97633626-97673748 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042411, HPA049031 Supported Supported Nucleoplasm
Cytosol Expressed in all testis: 32.3 -ANP32B APRIL, PHAPI2, SSP29 ENSG00000136938 Acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 9 97983361-98015943 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063133, HPA067561 Supported Approved Nucleoplasm
Centrosome
Cytosol Expressed in all lymph node: 267.6 -OR1L4 OR1L5, OR9-E ENSG00000136939 Olfactory receptor, family 1, subfamily L, member 4 9 122723990-122724925 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -PDCL DKFZp564M1863, PhLP ENSG00000136940 Phosducin-like 9 122798389-122828631 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021571, HPA021647, CAB026473 Uncertain Supported Cytosol Expressed in all endometrium: 23.8 -RPL35 L35 ENSG00000136942 Ribosomal protein L35 9 124857880-124861981 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006047 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all ovary: 2745.4 -CTSV CTSL2, CTSU ENSG00000136943 Cathepsin V 9 97029679-97039643 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017112 Uncertain Approved Nucleus
Nucleoli fibrillar center
Plasma membrane
Cytosol Tissue enhanced 0 cervix, uterine: 68.9;skin: 64.3;testis: 131.2 placenta: 25.7 -LMX1B NPS1 ENSG00000136944 LIM homeobox transcription factor 1, beta 9 126614443-126701032 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA073716 Approved Nucleus Tissue enhanced 0 breast: 5.8;salivary gland: 11.2 testis: 2.2 -ARPC5L ARC16-2, MGC3038 ENSG00000136950 Actin related protein 2/3 complex, subunit 5-like 9 124862130-124877733 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022013 Approved Expressed in all testis: 75.4 -ENPP2 ATX, PD-IALPHA, PDNP2 ENSG00000136960 Ectonucleotide pyrophosphatase/phosphodiesterase 2 8 119557086-119673453 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023700, HPA053652 Approved Approved Nucleus
Golgi apparatus
Actin filaments Expressed in all placenta: 372.6 -DSCC1 DCC1, hDCC1, MGC5528 ENSG00000136982 DNA replication and sister chromatid cohesion 1 8 119833976-119856010 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023780, HPA024401 Uncertain Approved Nucleoplasm Mixed lymph node: 8.0 -DERL1 DER-1, DER1, derlin-1, FLJ13784, MGC3067, PRO2577 ENSG00000136986 Derlin 1 8 123013164-123042423 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016562, CAB037269 Supported Validated Endoplasmic reticulum Expressed in all adipose tissue: 76.6 -MYC bHLHe39, c-Myc, MYCC ENSG00000136997 V-myc avian myelocytomatosis viral oncogene homolog 8 127735434-127741434 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000084, CAB010307, HPA055893, HPA066556 Supported Validated Nucleoplasm Expressed in all adipose tissue: 144.4 -NOV CCN3, IGFBP9 ENSG00000136999 Nephroblastoma overexpressed 8 119416306-119424353 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018449, HPA019684, CAB034423 Supported Supported Vesicles Tissue enriched 43 adrenal gland: 1396.8 prostate: 32.5 -IL33 C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV ENSG00000137033 Interleukin 33 9 6215786-6257983 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007057, HPA024426, HPA052386 Supported Approved Nucleoplasm
Cytosol Mixed placenta: 86.9 -TMEM261 C9orf123, MGC4730 ENSG00000137038 Transmembrane protein 261 9 7796490-7888380 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA014585 Approved Expressed in all thyroid gland: 17.3 -RANBP6 ENSG00000137040 RAN binding protein 6 9 6011043-6015625 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043748, HPA052684 Approved Supported Vesicles Expressed in all cerebral cortex: 26.3 -POLR1E FLJ13390, FLJ13970, PAF53, PRAF1 ENSG00000137054 Polymerase (RNA) I polypeptide E, 53kDa 9 37485935-37503697 Predicted intracellular proteins, Predicted membrane proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022527, HPA052400 Supported Supported Nucleus
Nucleoli fibrillar center Expressed in all ovary: 51.4 -PLAA DOA1, FLJ11281, FLJ12699, PLA2P, PLAP ENSG00000137055 Phospholipase A2-activating protein 9 26904083-26947463 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005035, HPA020994, HPA020996 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 37.8 -IL11RA ENSG00000137070 Interleukin 11 receptor, alpha 9 34650702-34661892 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA013162, CAB032830, HPA036652 Supported Expressed in all skin: 72.6 -UBAP2 bA176F3.5, FLJ22435, KIAA1491 ENSG00000137073 Ubiquitin associated protein 2 9 33921693-34048949 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021684 Approved Approved Cytosol Expressed in all testis: 46.5 -APTX AOA, AOA1, AXA1, EAOH, EOAHA, FLJ20157 ENSG00000137074 Aprataxin 9 32972606-33025168 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064930 Supported Validated Nucleus
Nucleoli Expressed in all testis: 24.3 -RNF38 ENSG00000137075 Ring finger protein 38 9 36336396-36487548 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA015853 Approved Supported Nucleoplasm Expressed in all testis: 116.2 -TLN1 ILWEQ, TLN ENSG00000137076 Talin 1 9 35696948-35732395 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002006, HPA004748 Supported Supported Plasma membrane
Focal adhesion sites
Microtubule organizing center
Cytosol Expressed in all smooth muscle: 202.0 -CCL21 6Ckine, CKb9, ECL, exodus-2, SCYA21, SLC, TCA4 ENSG00000137077 Chemokine (C-C motif) ligand 21 9 34709005-34710124 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005067, HPA051210 Supported Tissue enhanced 0 lymph node: 3206.9 tonsil: 984.2 -SIT1 SIT ENSG00000137078 Signaling threshold regulating transmembrane adaptor 1 9 35649295-35650950 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018506 Supported Group enriched 5 appendix: 25.6;lymph node: 56.9;spleen: 22.3;tonsil: 30.9 urinary bladder: 6.3 -IFNA21 IFN-alphaI ENSG00000137080 Interferon, alpha 21 9 21165637-21166660 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected parathyroid gland: 0.2 -DMRT1 CT154, DMT1 ENSG00000137090 Doublesex and mab-3 related transcription factor 1 9 841690-969090 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027850 Supported Tissue enriched 107 testis: 50.7 thyroid gland: 0.4 -DNAJB5 Hsc40 ENSG00000137094 DnaJ (Hsp40) homolog, subfamily B, member 5 9 34989641-34998900 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023818, HPA050794 Approved Approved Nucleus
Cytosol Mixed smooth muscle: 90.8 -SPAG8 BS-84, CT142, HSD-1, hSMP-1, SPAG3 ENSG00000137098 Sperm associated antigen 8 9 35808045-35812272 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA068012 Supported Group enriched 10 fallopian tube: 28.7;testis: 16.3 thyroid gland: 2.2 -DCTN3 DCTN-22 ENSG00000137100 Dynactin 3 (p22) 9 34613545-34620523 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044905 Approved Uncertain Nucleoli
Cytosol Expressed in all cerebral cortex: 130.1 -CD72 CD72b, LYB2 ENSG00000137101 CD72 molecule 9 35609533-35646810 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB002505, HPA044658 Supported Approved Nucleus
Mitochondria Group enriched 8 appendix: 26.2;lymph node: 72.0;spleen: 65.9;tonsil: 44.3 urinary bladder: 6.2 -TMEM8B C9orf127, NAG-5, NGX6 ENSG00000137103 Transmembrane protein 8B 9 35814451-35854847 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052130, HPA062701 Approved Approved Vesicles Expressed in all parathyroid gland: 26.7 -GRHPR GLXR, PH2 ENSG00000137106 Glyoxylate reductase/hydroxypyruvate reductase 9 37422666-37436990 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022971 Approved Approved Nucleoplasm
Cytosol Expressed in all liver: 322.8 -ALDH1B1 ALDH5, ALDHX ENSG00000137124 Aldehyde dehydrogenase 1 family, member B1 9 38392664-38398661 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021037 Approved Supported Nucleoplasm
Vesicles
Mitochondria Expressed in all smooth muscle: 176.4 -HINT2 ENSG00000137133 Histidine triad nucleotide binding protein 2 9 35812960-35815354 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020961, HPA059109 Supported Validated Mitochondria Expressed in all kidney: 82.4 -ARHGEF39 C9orf100, FLJ14642 ENSG00000137135 Rho guanine nucleotide exchange factor (GEF) 39 9 35658875-35675866 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061299 Uncertain Mixed rectum: 2.8 -IGFBPL1 bA113O24.1 ENSG00000137142 Insulin-like growth factor binding protein-like 1 9 38408994-38424447 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051354 Uncertain Approved Nucleoplasm
Vesicles Tissue enriched 8 thyroid gland: 31.3 cerebral cortex: 3.9 -DENND4C bA513M16.3, C9orf55, C9orf55B, FLJ20686 ENSG00000137145 DENN/MADD domain containing 4C 9 19230435-19373545 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA014917, HPA015096 Approved Supported Golgi apparatus
Vesicles
Cytosol Expressed in all parathyroid gland: 47.3 -RPS6 S6 ENSG00000137154 Ribosomal protein S6 9 19375715-19380254 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004027, HPA031153 Supported Validated Endoplasmic reticulum
Cytosol Expressed in all ovary: 4794.1 -CNPY3 CAG4A, TNRC5 ENSG00000137161 Canopy FGF signaling regulator 3 6 42929192-42939287 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016560 Uncertain Expressed in all spleen: 105.0 -FOXP4 FLJ40908 ENSG00000137166 Forkhead box P4 6 41546426-41602384 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007176 Approved Approved Nucleoplasm
Cytosol Expressed in all stomach: 37.2 -PPIL1 CYPL1 ENSG00000137168 Peptidylprolyl isomerase (cyclophilin)-like 1 6 36854827-36875024 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062916 Approved Nucleoli Expressed in all thyroid gland: 41.9 -KLC4 bA387M24.3, KNSL8 ENSG00000137171 Kinesin light chain 4 6 43040777-43075099 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030168, HPA030169 Supported Approved Mitochondria
Cytosol Expressed in all duodenum: 72.0 -KIF13A bA500C11.2 ENSG00000137177 Kinesin family member 13A 6 17759183-17987623 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029253, HPA029254 Uncertain Expressed in all parathyroid gland: 48.2 -ZSCAN9 PRD51, ZNF193 ENSG00000137185 Zinc finger and SCAN domain containing 9 6 28224886-28233482 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA054512, HPA059951 Uncertain Approved Nucleoplasm Expressed in all testis: 34.7 -PIM1 PIM ENSG00000137193 Pim-1 proto-oncogene, serine/threonine kinase 6 37170203-37175426 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA003941, CAB017040 Uncertain Supported Nucleoli
Cytosol Expressed in all bone marrow: 134.1 -GMPR ENSG00000137198 Guanosine monophosphate reductase 6 16238580-16295549 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000904, HPA021476 Uncertain Expressed in all skeletal muscle: 105.8 -CMTR1 FTSJD2, ISG95, KIAA0082, MTr1 ENSG00000137200 Cap methyltransferase 1 6 37433219-37482827 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029954, HPA029979, HPA029980 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 85.4 -TFAP2A AP-2, AP2TF, TFAP2 ENSG00000137203 Transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 6 10393186-10419659 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000326, HPA028850, HPA056871 Supported Validated Nucleoplasm Tissue enhanced 0 breast: 39.8;placenta: 42.1;skin: 76.2 epididymis: 25.2 -SLC22A7 NLT, OAT2 ENSG00000137204 Solute carrier family 22 (organic anion transporter), member 7 6 43295694-43305538 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030220 Approved Group enriched 63 kidney: 50.1;liver: 167.4 testis: 1.7 -YIPF3 C6orf109, dJ337H4.3, DKFZp566C243, FinGER3, KLIP1 ENSG00000137207 Yip1 domain family, member 3 6 43511827-43516990 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014859, HPA063699 Supported Validated Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 140.3 -TMEM14B MGC1223 ENSG00000137210 Transmembrane protein 14B 6 10747759-10852753 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Expressed in all thyroid gland: 204.2 -TMEM63B C6orf110, dJ421H19.2, DKFZp434P0531 ENSG00000137216 Transmembrane protein 63B 6 44126914-44155519 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029249, HPA029250, HPA029251 Uncertain Validated Plasma membrane
Actin filaments Expressed in all lung: 59.2 -FRS3 FRS2B, FRS2beta, SNT-2 ENSG00000137218 Fibroblast growth factor receptor substrate 3 6 41770176-41786542 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA030162, HPA030174 Approved Uncertain Nucleoplasm Mixed testis: 22.0 -TJAP1 PILT, TJP4 ENSG00000137221 Tight junction associated protein 1 (peripheral) 6 43477523-43506556 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030164, HPA030165, HPA030166 Supported Approved Golgi apparatus Expressed in all endometrium: 33.7 -CAPN11 ENSG00000137225 Calpain 11 6 44158811-44184402 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB018070, HPA030955 Supported Tissue enriched 32 testis: 54.7 breast: 1.6 -TINAG ENSG00000137251 Tubulointerstitial nephritis antigen 6 54307859-54390152 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035427, HPA041055 Approved Approved Vesicles Tissue enriched 7 kidney: 112.9 small intestine: 16.0 -HCRTR2 OX2R ENSG00000137252 Hypocretin (orexin) receptor 2 6 55106460-55282620 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA054516 Supported Not detected kidney: 0.6 -KIAA0319 NMIG ENSG00000137261 KIAA0319 6 24544104-24646155 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 cerebral cortex: 15.8 fallopian tube: 2.8 -IRF4 LSIRF, MUM1 ENSG00000137265 Interferon regulatory factor 4 6 391739-411447 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002038, HPA002698, CAB013508 Supported Supported Nucleoplasm Tissue enhanced 0 lymph node: 27.4 tonsil: 25.0 -SLC22A23 C6orf85, FLJ22174 ENSG00000137266 Solute carrier family 22, member 23 6 3268962-3457022 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014697 Approved Approved Nucleoplasm
Vesicles
Cytosol Expressed in all stomach: 28.2 -TUBB2A dJ40E16.7, TUBB, TUBB2 ENSG00000137267 Tubulin, beta 2A class IIa 6 3153669-3157526 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015339, HPA043640, HPA046280 Supported Validated Microtubules Tissue enriched 9 cerebral cortex: 624.8 skin: 72.1 -LRRC1 dJ523E19.1, FLJ10775, FLJ11834, LANO ENSG00000137269 Leucine rich repeat containing 1 6 53794497-53924121 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031603, HPA031604 Supported Supported Cytosol Mixed parathyroid gland: 41.1 -GCM1 GCMA, hGCMa ENSG00000137270 Glial cells missing homolog 1 (Drosophila) 6 53126964-53148829 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA011343 Supported Approved Vesicles Tissue enriched 21 placenta: 29.0 kidney: 1.4 -FOXF2 FKHL6, FREAC2 ENSG00000137273 Forkhead box F2 6 1389834-1395597 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed lung: 18.5 -BPHL Bph-rp, MCNAA ENSG00000137274 Biphenyl hydrolase-like (serine hydrolase) 6 3118374-3153578 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036752, HPA036753 Supported Approved Nucleoplasm
Mitochondria Expressed in all kidney: 111.5 -RIPK1 RIP ENSG00000137275 Receptor (TNFRSF)-interacting serine-threonine kinase 1 6 3063991-3115187 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010302, HPA015257 Supported Validated Plasma membrane
Cytosol Expressed in all skin: 26.1 -TUBB2B bA506K6.1, DKFZp566F223, MGC8685 ENSG00000137285 Tubulin, beta 2B class IIb 6 3224261-3231730 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043640, HPA046280 Supported Approved Microtubules Tissue enriched 6 cerebral cortex: 309.5 epididymis: 51.0 -UQCC2 bA6B20.2, C6orf125, Cbp6, M19, MGC14833, MNF1 ENSG00000137288 Ubiquinol-cytochrome c reductase complex assembly factor 2 6 33694293-33711727 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039111 Uncertain Supported Nuclear bodies
Mitochondria Expressed in all testis: 130.8 -HMGA1 HMGIY ENSG00000137309 High mobility group AT-hook 1 6 34236873-34246231 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB032200 Uncertain Approved Nucleus
Nucleoli Expressed in all lymph node: 165.8 -TCF19 SC1 ENSG00000137310 Transcription factor 19 6 31158542-31167159 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 11.4 skin: 6.7 -FLOT1 ENSG00000137312 Flotillin 1 6 30727709-30742733 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001393, CAB007766 Supported Approved Golgi apparatus
Vesicles
Plasma membrane Expressed in all cervix: 18.8 -IER3 DIF-2, IEX-1, IEX-1L, PRG1 ENSG00000137331 Immediate early response 3 6 30743199-30744554 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043847 Approved Tissue enhanced 0 appendix: 20.9 adipose tissue: 11.3 -MDC1 Em:AB023051.5, KIAA0170, NFBD1 ENSG00000137337 Mediator of DNA-damage checkpoint 1 6 30699807-30717889 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006915 Supported Supported Nucleoplasm
Nuclear bodies Tissue enhanced 0 testis: 9.7 skin: 3.3 -PGBD1 dJ874C20.4, HUCEP-4, SCAND4 ENSG00000137338 PiggyBac transposable element derived 1 6 28281572-28302549 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA007267 Uncertain Approved Nucleoplasm
Cytosol Mixed smooth muscle: 7.9 -ATAT1 C6orf134, Em:AB023049.7, FLJ13158, MEC17 ENSG00000137343 Alpha tubulin acetyltransferase 1 6 30626842-30646823 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046816, HPA050999 Approved Approved Golgi apparatus
Cytosol Mixed epididymis: 4.3 -TPMT ENSG00000137364 Thiopurine S-methyltransferase 6 18128311-18155074 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019851 Approved Expressed in all thyroid gland: 129.4 -CLPS ENSG00000137392 Colipase, pancreatic 6 35794982-35797344 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010512 Approved Tissue enriched 264 pancreas: 56674.8 ovary: 215.0 -RNF144B bA528A10.3, IBRDC2 ENSG00000137393 Ring finger protein 144B 6 18387350-18468874 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB046013, HPA054127, HPA072469 Uncertain Approved Nucleoli
Mitochondria Tissue enhanced 0 thyroid gland: 67.9 breast: 34.9 -NRM NRM29 ENSG00000137404 Nurim (nuclear envelope membrane protein) 6 30688047-30691420 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072545, HPA073982 Validated Nuclear membrane Mixed skin: 1.6 -MTCH1 CGI-64, PSAP, SLC25A49 ENSG00000137409 Mitochondrial carrier 1 6 36968141-36986298 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015971 Approved Expressed in all thyroid gland: 568.7 -VARS2 DKFZP434L1435, G7a, KIAA1885, VARS2L, VARSL ENSG00000137411 Valyl-tRNA synthetase 2, mitochondrial 6 30908242-30926459 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062449, HPA070267 Approved Approved Mitochondria Mixed esophagus: 5.2 -TAF8 FLJ32821, TAF(II)43, TBN ENSG00000137413 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 6 42050513-42087461 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031730, HPA031731, HPA031734 Supported Validated Nucleus Expressed in all parathyroid gland: 24.9 -FAM8A1 AHCP ENSG00000137414 Family with sequence similarity 8, member A1 6 17600355-17611719 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044698 Supported Golgi apparatus Expressed in all endometrium: 45.3 -C6orf52 ENSG00000137434 Chromosome 6 open reading frame 52 6 10671418-10694797 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051142 Uncertain Approved Nuclear speckles Tissue enhanced 0 testis: 17.9 fallopian tube: 10.5 -FGFBP1 FGFBP, HBP17 ENSG00000137440 Fibroblast growth factor binding protein 1 4 15935569-15938740 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004332 Supported Tissue enriched 7 esophagus: 299.1 skin: 40.3 -FGFBP2 KSP37 ENSG00000137441 Fibroblast growth factor binding protein 2 4 15960243-15969309 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039180 Uncertain Tissue enhanced 0 bone marrow: 29.2 spleen: 18.3 -CPEB2 ENSG00000137449 Cytoplasmic polyadenylation element binding protein 2 4 15002674-15070153 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA072513 Supported Nucleoplasm
Cytosol Tissue enhanced 0 testis: 41.5 parathyroid gland: 23.7 -FHDC1 KIAA1727 ENSG00000137460 FH2 domain containing 1 4 152936352-152979696 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008527 Uncertain Tissue enhanced 0 thyroid gland: 26.6 lung: 12.9 -TLR2 CD282, TIL4 ENSG00000137462 Toll-like receptor 2 4 153701500-153705699 CD markers, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060231, HPA071546 Supported Nucleus
Mitochondria Tissue enhanced 0 appendix: 53.7 bone marrow: 34.9 -MGARP C4orf49, CESP-1, HUMMR, OSAP ENSG00000137463 Mitochondria-localized glutamic acid-rich protein 4 139266163-139280338 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015994 Supported Supported Mitochondria Tissue enriched 10 adrenal gland: 268.2 ovary: 27.0 -TTC29 NYD-SP14 ENSG00000137473 Tetratricopeptide repeat domain 29 4 146706638-146945882 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037006, HPA061473 Uncertain Group enriched 27 fallopian tube: 33.8;testis: 150.4 lung: 3.4 -MYO7A DFNA11, DFNB2, NSRD2, USH1B ENSG00000137474 Myosin VIIA 11 77128264-77215239 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028918, CAB034059 Uncertain Supported Cytosol Tissue enhanced 0 adrenal gland: 26.9;placenta: 20.7 testis: 17.2 -FCHSD2 KIAA0769, SH3MD3 ENSG00000137478 FCH and double SH3 domains 2 11 72836745-73142261 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038545, HPA038546 Uncertain Approved Nuclear speckles
Plasma membrane
Actin filaments
Focal adhesion sites Expressed in all spleen: 65.0 -ARRB1 ARR1 ENSG00000137486 Arrestin, beta 1 11 75264182-75351705 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003763, HPA049318 Approved Supported Nucleoplasm Expressed in all lung: 80.5 -SLCO2B1 OATP-B, OATP2B1, SLC21A9 ENSG00000137491 Solute carrier organic anion transporter family, member 2B1 11 75100563-75206549 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020659 Uncertain Expressed in all liver: 123.0 -PRKRIR DAP4, P52rIPK, THAP12 ENSG00000137492 Protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 11 76349956-76380971 Plasma proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008758 Approved Approved Nucleoplasm Expressed in all endometrium: 42.6 -ANKRD42 FLJ37874, PPP1R79, SARP ENSG00000137494 Ankyrin repeat domain 42 11 83193739-83260694 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039917 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 testis: 71.7 epididymis: 28.4 -IL18BP IL18BPa ENSG00000137496 Interleukin 18 binding protein 11 71998541-72005715 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025980, HPA041061 Supported Approved Endoplasmic reticulum Tissue enhanced 0 spleen: 57.0 appendix: 34.0 -NUMA1 ENSG00000137497 Nuclear mitotic apparatus protein 1 11 72002864-72080693 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019841, HPA019859, HPA029912 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 243.4 -CCDC90B MDS011, MDS025 ENSG00000137500 Coiled-coil domain containing 90B 11 83259097-83286407 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011130, HPA011931 Supported Validated Mitochondria Expressed in all testis: 96.2 -SYTL2 CHR11SYT, exophilin-4, FLJ20163, FLJ21219, KIAA1597, MGC102768, PPP1R151, SGA72M, SLP2 ENSG00000137501 Synaptotagmin-like 2 11 85694224-85811159 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039651 Approved Nucleus
Golgi apparatus
Plasma membrane Tissue enhanced 0 stomach: 120.8 rectum: 82.7 -RAB30 ENSG00000137502 RAB30, member RAS oncogene family 11 82973133-83071923 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054514, HPA060565 Approved Validated Vesicles Expressed in all tonsil: 29.7 -CREBZF ZF ENSG00000137504 CREB/ATF bZIP transcription factor 11 85659708-85682908 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA021526, HPA063652 Uncertain Approved Nucleus
Mitochondria Expressed in all parathyroid gland: 31.1 -LRRC32 D11S833E, GARP ENSG00000137507 Leucine rich repeat containing 32 11 76657524-76670747 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all placenta: 75.9 -PRCP HUMPCP, PCP ENSG00000137509 Prolylcarboxypeptidase (angiotensinase C) 11 82823502-82970584 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017065 Approved Expressed in all placenta: 220.6 -NARS2 DFNB94, FLJ23441, SLM5 ENSG00000137513 Asparaginyl-tRNA synthetase 2, mitochondrial (putative) 11 78435961-78574874 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026793 Supported Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all kidney: 19.7 -RNF121 FLJ11099 ENSG00000137522 Ring finger protein 121 11 71928701-71997597 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046041 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Expressed in all parathyroid gland: 27.9 -MRPL15 HSPC145, L15mt, MRP-L15, MRP-L7, RPML7 ENSG00000137547 Mitochondrial ribosomal protein L15 8 54135210-54147901 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044425 Supported Expressed in all heart muscle: 82.3 -PI15 P25TI ENSG00000137558 Peptidase inhibitor 15 8 74824537-74855029 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006593, HPA030057 Uncertain Tissue enhanced 0 appendix: 74.8;prostate: 45.0;smooth muscle: 66.9 endometrium: 32.7 -TTPA AVED ENSG00000137561 Tocopherol (alpha) transfer protein 8 63048553-63086053 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 17 liver: 82.6 rectum: 4.9 -GGH ENSG00000137563 Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 8 63015079-63039171 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB019296, HPA025226 Approved Tissue enhanced 0 kidney: 89.2 liver: 62.8 -SLCO5A1 OATP-J, OATP5A1, OATPRP4, SLC21A15 ENSG00000137571 Solute carrier organic anion transporter family, member 5A1 8 69667047-69835064 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA025062 Uncertain Tissue enhanced 0 prostate: 3.6 skeletal muscle: 2.6 -SULF1 KIAA1077, SULF-1 ENSG00000137573 Sulfatase 1 8 69466624-69660915 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054728 Supported Tissue enhanced 0 smooth muscle: 104.3 prostate: 79.1 -TGS1 NCOA6IP, PIMT ENSG00000137574 Trimethylguanosine synthase 1 8 55773142-55825448 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025024, HPA029824 Supported Validated Nucleus
Cytosol Mixed lymph node: 15.5 -SDCBP SYCL ENSG00000137575 Syndecan binding protein (syntenin) 8 58552924-58582860 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012245, HPA023840 Approved Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all placenta: 362.0 -NEK1 KIAA1901, NY-REN-55 ENSG00000137601 NIMA-related kinase 1 4 169393275-169612629 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020873, HPA040413 Approved Approved Nuclear membrane
Nucleoli Mixed testis: 22.3 -DDX60 FLJ20035 ENSG00000137628 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 4 168216293-168318807 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046952 Approved Approved Intermediate filaments
Cytosol Mixed stomach: 46.0 -NXPE4 C11orf33, FAM55D, FLJ20127 ENSG00000137634 Neurexophilin and PC-esterase domain family, member 4 11 114570591-114595762 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042801 Approved Group enriched 9 colon: 142.1;rectum: 161.0;salivary gland: 38.4 appendix: 12.4 -SORL1 C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1 ENSG00000137642 Sortilin-related receptor, L(DLR class) A repeats containing 11 121452203-121633693 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB011500, HPA031321 Uncertain Approved Nucleoplasm
Cell Junctions Mixed cervix: 67.4 -TMPRSS4 MT-SP2, TMPRSS3 ENSG00000137648 Transmembrane protease, serine 4 11 118077012-118121890 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006238 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 rectum: 78.4;urinary bladder: 80.0 esophagus: 74.1 -BUD13 Cwc26, fSAP71, MGC13125 ENSG00000137656 BUD13 homolog 11 116748170-116772988 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038340, HPA038341 Approved Validated Nucleus Expressed in all testis: 39.3 -TRPC6 FSGS2, TRP6 ENSG00000137672 Transient receptor potential cation channel, subfamily C, member 6 11 101451564-101872562 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045098, HPA062164 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 placenta: 29.8 lung: 20.0 -MMP7 MPSL1, PUMP-1 ENSG00000137673 Matrix metallopeptidase 7 11 102520508-102530753 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025869, HPA051358 Supported Approved Nucleoplasm
Vesicles Tissue enhanced 0 gallbladder: 824.4 breast: 201.5 -MMP20 ENSG00000137674 Matrix metallopeptidase 20 11 102576835-102625332 Disease related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 5 breast: 1.2;testis: 1.1 tonsil: 0.2 -MMP27 ENSG00000137675 Matrix metallopeptidase 27 11 102691487-102705806 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA069097 Approved Group enriched 5 breast: 6.0;skin: 2.8 bone marrow: 0.8 -C11orf70 MGC13040 ENSG00000137691 Chromosome 11 open reading frame 70 11 102047443-102084560 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038585 Supported Approved Centrosome Tissue enhanced 0 fallopian tube: 45.9;testis: 54.5 epididymis: 12.9 -DCUN1D5 FLJ32431, MGC2714 ENSG00000137692 DCN1, defective in cullin neddylation 1, domain containing 5 11 103062076-103092215 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050863 Approved Approved Nucleus
Nucleoli Expressed in all testis: 34.4 -YAP1 YAP65 ENSG00000137693 Yes-associated protein 1 11 102110461-102233423 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009370, HPA038885 Approved Supported Nucleus
Nucleoli Mixed smooth muscle: 145.2 -TRIM29 ATDC, FLJ36085 ENSG00000137699 Tripartite motif containing 29 11 120111275-120185529 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020053 Supported Supported Nucleoplasm
Intermediate filaments Group enriched 6 esophagus: 401.8;skin: 456.6 tonsil: 71.2 -SLC37A4 G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d ENSG00000137700 Solute carrier family 37 (glucose-6-phosphate transporter), member 4 11 119024114-119030906 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038939, HPA038940 Approved Approved Mitochondria Tissue enhanced 0 duodenum: 31.4;kidney: 36.1 epididymis: 20.7 -BTG4 PC3B ENSG00000137707 B-cell translocation gene 4 11 111467526-111512354 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057157 Approved Endoplasmic reticulum
Golgi apparatus Tissue enriched 17 testis: 47.2 fallopian tube: 2.7 -POU2F3 Epoc-1, OCT11, PLA-1, Skn-1a ENSG00000137709 POU class 2 homeobox 3 11 120236640-120319944 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA019652 Supported Group enriched 12 parathyroid gland: 15.3;skin: 72.5 seminal vesicle: 3.8 -RDX DFNB24 ENSG00000137710 Radixin 11 110174880-110296722 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000263, HPA000763, CAB037312 Supported Validated Plasma membrane Expressed in all adrenal gland: 199.3 -PPP2R1B PP2A-Abeta, PR65B ENSG00000137713 Protein phosphatase 2, regulatory subunit A, beta 11 111726908-111766427 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004034, HPA018908 Approved Approved Nucleus
Plasma membrane
Centrosome
Cytosol Expressed in all testis: 98.2 -FDX1 ADX, FDX ENSG00000137714 Ferredoxin 1 11 110429883-110464881 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041630, HPA062087 Supported Validated Mitochondria Tissue enriched 11 adrenal gland: 389.2 seminal vesicle: 36.1 -C11orf1 FLJ23499 ENSG00000137720 Chromosome 11 open reading frame 1 11 111878935-111885975 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA038410, HPA057519 Uncertain Validated Nucleoplasm Expressed in all testis: 103.8 -FXYD6 ENSG00000137726 FXYD domain containing ion transport regulator 6 11 117836976-117877486 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041334, HPA042284 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 698.7 -ARHGAP20 KIAA1391 ENSG00000137727 Rho GTPase activating protein 20 11 110577042-110713189 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038458, HPA038459, HPA076303 Uncertain Approved Mitochondria Mixed testis: 15.4 -FXYD2 ATP1G1, HOMG2, MGC12372 ENSG00000137731 FXYD domain containing ion transport regulator 2 11 117800844-117828698 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064218, HPA068838 Supported Approved Mitochondria Group enriched 6 gallbladder: 575.2;kidney: 1428.7;salivary gland: 383.4 pancreas: 134.6 -MMP13 CLG3 ENSG00000137745 Matrix metallopeptidase 13 11 102942995-102955734 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lung: 1.5;urinary bladder: 1.4 testis: 0.3 -TMPRSS13 MSPL, TMPRSS11 ENSG00000137747 Transmembrane protease, serine 13 11 117900643-117929459 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 35.1 cervix: 10.0 -CASP1 ICE, IL1BC ENSG00000137752 Caspase 1, apoptosis-related cysteine peptidase 11 105025443-105035250 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002685, HPA003056 Approved Supported Nucleoplasm
Cytosol Mixed small intestine: 142.8 -CASP5 ICE(rel)III ENSG00000137757 Caspase 5, apoptosis-related cysteine peptidase 11 104994235-105023168 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040937 Uncertain Group enriched 6 appendix: 20.7;colon: 16.2;duodenum: 10.4;rectum: 14.7;small intestine: 19.3 smooth muscle: 2.6 -ALKBH8 MGC10235, TRM9, TRMT9 ENSG00000137760 AlkB homolog 8, tRNA methyltransferase 11 107502726-107565746 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038724, HPA038725, HPA061514 Approved Supported Nucleoplasm
Nuclear bodies Mixed parathyroid gland: 9.4 -MAP2K5 HsT17454, MAPKK5, MEK5, PRKMK5 ENSG00000137764 Mitogen-activated protein kinase kinase 5 15 67542709-67807123 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022094, HPA027347, HPA027755 Supported Approved Nucleoli
Microtubules Expressed in all parathyroid gland: 32.1 -UNC13C DKFZp547H074, Munc13-3 ENSG00000137766 Unc-13 homolog C (C. elegans) 15 54012904-54633414 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041516 Uncertain Group enriched 15 cerebral cortex: 17.4;testis: 15.2 thyroid gland: 1.1 -SQRDL CGI-44 ENSG00000137767 Sulfide quinone reductase-like (yeast) 15 45631148-45691294 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017079, HPA041589 Supported Validated Mitochondria Expressed in all colon: 196.9 -CTDSPL2 FLJ10523, HSPC129 ENSG00000137770 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 15 44427234-44529038 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040763, HPA062198 Approved Validated Nucleoplasm Expressed in all testis: 37.5 -SLTM FLJ13213, Met ENSG00000137776 SAFB-like, transcription modulator 15 58879045-58933653 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040256, HPA040381 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 65.6 -THBS1 THBS, THBS-1, TSP, TSP-1, TSP1 ENSG00000137801 Thrombospondin 1 15 39581079-39599466 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033678, HPA059756 Approved Approved Plasma membrane Expressed in all appendix: 585.7 -MAPKBP1 KIAA0596 ENSG00000137802 Mitogen-activated protein kinase binding protein 1 15 41774434-41827855 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030832, HPA030833 Approved Approved Nucleoli Mixed testis: 34.0 -NUSAP1 ANKT, BM037, FLJ13421, LNP, NuSAP1, PRO0310p1, Q0310, SAPL ENSG00000137804 Nucleolar and spindle associated protein 1 15 41332694-41381050 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042904 Supported Supported Nucleus
Nucleoli fibrillar center
Cytosol Tissue enhanced 0 bone marrow: 75.5 lymph node: 57.9 -NDUFAF1 CGI-65, CIA30 ENSG00000137806 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 15 41387349-41402519 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039933, HPA040064 Supported Validated Cytosol Expressed in all testis: 45.2 -KIF23 KNSL5, MKLP-1, MKLP1 ENSG00000137807 Kinesin family member 23 15 69414246-69448427 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010414, HPA045208, HPA068831 Approved Validated Nucleoplasm Mixed testis: 19.6 -ITGA11 HsT18964 ENSG00000137809 Integrin, alpha 11 15 68296533-68432162 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051813 Uncertain Tissue enhanced 0 cervix, uterine: 54.4;endometrium: 52.2;smooth muscle: 74.7 epididymis: 22.7 -CASC5 AF15Q14, CT29, D40, hKNL-1, hSpc105, KNL1, PPP1R55, Spc7 ENSG00000137812 Cancer susceptibility candidate 5 15 40594020-40664342 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026624, HPA049647 Supported Validated Nucleoplasm
Nuclear bodies Tissue enriched 7 testis: 31.6 lymph node: 4.5 -HAUS2 C15orf25, CEP27, FLJ10460, HsT17025 ENSG00000137814 HAUS augmin-like complex, subunit 2 15 42548810-42569994 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039965 Approved Approved Nucleoplasm
Centrosome
Cytosol Expressed in all bone marrow: 22.5 -RTF1 KIAA0252 ENSG00000137815 RTF1 homolog, Paf1/RNA polymerase II complex component 15 41408408-41483563 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006714 Approved Approved Nucleus
Cytosol Expressed in all parathyroid gland: 62.7 -PARP6 pART17 ENSG00000137817 Poly (ADP-ribose) polymerase family, member 6 15 72241181-72272999 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA026991 Approved Approved Plasma membrane Expressed in all testis: 46.7 -RPLP1 LP1 ENSG00000137818 Ribosomal protein, large, P1 15 69452784-69456194 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003368 Uncertain Validated Endoplasmic reticulum
Cytosol Expressed in all ovary: 1839.8 -PAQR5 FLJ20190, MPRG ENSG00000137819 Progestin and adipoQ receptor family member V 15 69298947-69407780 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA076729 Approved Vesicles Tissue enhanced 0 kidney: 55.6 adrenal gland: 20.9 -LRRC49 FLJ20156 ENSG00000137821 Leucine rich repeat containing 49 15 70853239-71053657 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015596 Uncertain Mixed epididymis: 35.0 -TUBGCP4 76P, FLJ14797 ENSG00000137822 Tubulin, gamma complex associated protein 4 15 43369221-43409771 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043212 Approved Supported Centrosome Expressed in all parathyroid gland: 12.2 -RMDN3 FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3 ENSG00000137824 Regulator of microtubule dynamics 3 15 40735884-40755851 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009975 Supported Validated Mitochondria Expressed in all cerebral cortex: 58.3 -ITPKA IP3-3KA, IP3KA ENSG00000137825 Inositol-trisphosphate 3-kinase A 15 41493393-41503551 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040454 Approved Approved Approved Vesicles Tissue enhanced 0 cerebral cortex: 25.8;duodenum: 18.2;small intestine: 20.2 stomach: 9.1 -UACA FLJ10128, KIAA1561 ENSG00000137831 Uveal autoantigen with coiled-coil domains and ankyrin repeats 15 70654554-70763593 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041412, HPA043503 Uncertain Supported Nucleus
Cytosol Mixed thyroid gland: 59.4 -SMAD6 HsT17432, MADH6, MADH7 ENSG00000137834 SMAD family member 6 15 66702228-66782848 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA061917 Supported Nucleus
Nuclear bodies
Golgi apparatus Tissue enhanced 0 lung: 16.9 placenta: 10.6 -PLCB2 FLJ38135 ENSG00000137841 Phospholipase C, beta 2 15 40278176-40307935 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009443, HPA041298 Approved Approved Cytosol Tissue enhanced 0 spleen: 56.7 appendix: 39.4 -TMEM62 FLJ23375 ENSG00000137842 Transmembrane protein 62 15 43123279-43185146 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044461, HPA062359 Approved Approved Nucleus
Nucleoli fibrillar center
Nuclear bodies
Cytoplasmic bodies Expressed in all breast: 27.2 -PAK6 PAK5 ENSG00000137843 P21 protein (Cdc42/Rac)-activated kinase 6 15 40238759-40277487 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031124 Approved Approved Nucleus
Nucleoli fibrillar center
Cell Junctions Mixed cerebral cortex: 28.7 -ADAM10 CD156c, HsT18717, kuz, MADM ENSG00000137845 ADAM metallopeptidase domain 10 15 58588807-58749978 Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001709, HPA050670 Approved Supported Vesicles
Plasma membrane Expressed in all thyroid gland: 47.8 -DUOX1 LNOX1, NOXEF1, THOX1 ENSG00000137857 Dual oxidase 1 15 45129933-45165576 Enzymes, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023544 Approved Tissue enhanced 0 skin: 96.8;thyroid gland: 92.3 esophagus: 73.4 -SLC28A2 CNT2, HCNT2, HsT17153, SPNT1 ENSG00000137860 Solute carrier family 28 (concentrative nucleoside transporter), member 2 15 45252230-45277845 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA046068, HPA055623 Supported Tissue enhanced 0 duodenum: 66.8;rectum: 37.9;small intestine: 100.1 stomach: 21.4 -STRA6 FLJ12541 ENSG00000137868 Stimulated by retinoic acid 6 15 74179466-74212267 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040839 Approved Approved Nucleus
Cytosol Tissue enhanced 0 cervix, uterine: 37.3;placenta: 20.4 endometrium: 13.5 -CYP19A1 ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM ENSG00000137869 Cytochrome P450, family 19, subfamily A, polypeptide 1 15 51208057-51338610 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000355, HPA051194 Supported Approved Vesicles Tissue enriched 14 placenta: 173.9 testis: 12.4 -ZNF280D FLJ20086, SUHW4, ZNF634 ENSG00000137871 Zinc finger protein 280D 15 56630181-56918571 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030233 Approved Approved Nucleoplasm
Golgi apparatus
Centrosome
Cytosol Expressed in all endometrium: 31.6 -SEMA6D FLJ11598, KIAA1479 ENSG00000137872 Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 15 47184101-47774223 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043109 Approved Golgi apparatus
Plasma membrane Tissue enhanced 0 placenta: 64.3 small intestine: 45.7 -BCL2L10 BCL-B, Boo, Diva ENSG00000137875 BCL2-like 10 (apoptosis facilitator) 15 52109263-52112775 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042222 Approved Tissue enhanced 0 skin: 6.1 kidney: 3.3 -RSL24D1 C15orf15, HRP-L30-iso, L30, RPL24, RPL24L ENSG00000137876 Ribosomal L24 domain containing 1 15 55180806-55197067 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062724, HPA063392 Supported Validated Nucleus
Nucleoli Expressed in all ovary: 124.1 -SPTBN5 BSPECV, HUBSPECV, HUSPECV ENSG00000137877 Spectrin, beta, non-erythrocytic 5 15 41848144-41894077 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed parathyroid gland: 1.4 -GCOM1 FLJ30973, GRINL1A, MYZAP-POLR2M ENSG00000137878 GRINL1A complex locus 1 15 57591908-57714745 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA039827, HPA068141 Approved Approved Nucleoplasm Mixed adipose tissue: 5.0 -GCHFR GFRP, HsT16933 ENSG00000137880 GTP cyclohydrolase I feedback regulator 15 40764020-40767710 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046258 Approved Supported Nucleoplasm Expressed in all small intestine: 63.7 -BCAR3 NSP2, SH2D3B ENSG00000137936 Breast cancer anti-estrogen resistance 3 1 93561786-93847150 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014858 Approved Approved Plasma membrane
Centrosome
Cytosol Mixed adipose tissue: 32.5 -TTLL7 FLJ23033 ENSG00000137941 Tubulin tyrosine ligase-like family member 7 1 83865028-83999150 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052249, HPA059321 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 47.0 smooth muscle: 10.6 -FNBP1L C1orf39, FLJ20275, TOCA1 ENSG00000137942 Formin binding protein 1-like 1 93448131-93554661 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065273 Approved Approved Vesicles Expressed in all thyroid gland: 53.6 -CCBL2 KAT3, RBM1, RP11-82K18.3 ENSG00000137944 Cysteine conjugate-beta lyase 2 1 88935773-88992953 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026538, HPA027168 Supported Approved Nucleoli
Cytosol Expressed in all parathyroid gland: 42.1 -GTF2B TFIIB ENSG00000137947 General transcription factor IIB 1 88852932-88891944 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061626 Supported Supported Nucleus
Nuclear bodies Expressed in all bone marrow: 47.7 -BRDT BRD6, CT9 ENSG00000137948 Bromodomain, testis-specific 1 91949371-92014426 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB012237 Approved Tissue enriched 123 testis: 234.6 bone marrow: 1.9 -RABGGTB ENSG00000137955 Rab geranylgeranyltransferase, beta subunit 1 75786197-75795079 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026585, HPA027167, HPA030793 Approved Approved Supported Vesicles Expressed in all kidney: 68.8 -IFI44L C1orf29, GS3686 ENSG00000137959 Interferon-induced protein 44-like 1 78619922-78646145 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA053247, HPA060372 Approved Approved Nucleoplasm Mixed spleen: 32.9 -GIPC2 FLJ20075, SEMCAP-2 ENSG00000137960 GIPC PDZ domain containing family, member 2 1 77979542-78138449 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051212, HPA062684 Approved Approved Nucleus
Cytosol Mixed small intestine: 41.8 -ARHGAP29 PARG1 ENSG00000137962 Rho GTPase activating protein 29 1 94148988-94275068 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026534 Approved Approved Nucleus
Plasma membrane
Centrosome
Cytosol Mixed spleen: 50.5 -IFI44 MTAP44, p44, TLDC5 ENSG00000137965 Interferon-induced protein 44 1 78649796-78664078 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA027148, HPA043858 Approved Approved Nucleoplasm Expressed in all spleen: 90.2 -SLC44A5 CTL5, MGC34032 ENSG00000137968 Solute carrier family 44, member 5 1 75202131-75611116 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047455, HPA051011 Uncertain Approved Cytosol Tissue enhanced 0 skin: 12.6 testis: 8.0 -CLCA2 CLCRG2 ENSG00000137975 Chloride channel accessory 2 1 86424086-86456558 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047192 Supported Supported Nucleus
Cell Junctions Tissue enhanced 0 esophagus: 126.9;skin: 102.9 tonsil: 23.5 -DNASE2B DLAD ENSG00000137976 Deoxyribonuclease II beta 1 84398532-84415018 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 salivary gland: 73.5 prostate: 11.3 -DBT ENSG00000137992 Dihydrolipoamide branched chain transacylase E2 1 100186919-100249834 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026481, HPA026485, HPA026533 Supported Supported Mitochondria Expressed in all kidney: 19.6 -RTCA RPC, RTC1, RTCD1 ENSG00000137996 RNA 3'-terminal phosphate cyclase 1 100266207-100292769 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027982, HPA027990, HPA028151 Uncertain Validated Nucleus Expressed in all duodenum: 36.0 -IFT172 NPHP17, osm-1, SLB, wim ENSG00000138002 Intraflagellar transport 172 2 27444371-27489789 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044893 Uncertain Approved Vesicles Expressed in all parathyroid gland: 33.2 -EPT1 KIAA1724, SELI, SEPI ENSG00000138018 Ethanolaminephosphotransferase 1 2 26308547-26395891 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 33.1 -CGREF1 CGR11 ENSG00000138028 Cell growth regulator with EF-hand domain 1 2 27098889-27119115 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008241 Uncertain Tissue enhanced 0 cerebral cortex: 44.9 stomach: 11.6 -HADHB MTPB ENSG00000138029 Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2 26243170-26290468 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037539, HPA037540, HPA066099 Supported Supported Mitochondria Expressed in all heart muscle: 313.2 -KHK ENSG00000138030 Ketohexokinase (fructokinase) 2 27086747-27100772 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007040 Supported Approved Cytosol Group enriched 11 duodenum: 116.2;kidney: 111.0;liver: 97.3;small intestine: 135.8 cerebral cortex: 10.1 -ADCY3 AC3 ENSG00000138031 Adenylate cyclase 3 2 24819169-24919839 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010223 Approved Expressed in all placenta: 121.3 -PPM1B PP2CB, PP2CBETA, PPC2BETAX ENSG00000138032 Protein phosphatase, Mg2+/Mn2+ dependent, 1B 2 44167969-44244384 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016745 Approved Approved Nucleoli
Cytosol Expressed in all parathyroid gland: 80.9 -PNPT1 DFNB70, old-35, OLD35, PNPase ENSG00000138035 Polyribonucleotide nucleotidyltransferase 1 2 55634265-55693910 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033424, HPA034602, HPA034603 Supported Validated Mitochondria Expressed in all thyroid gland: 10.0 -DYNC2LI1 CGI-60, D2LIC, DKFZP564A033, LIC3 ENSG00000138036 Dynein, cytoplasmic 2, light intermediate chain 1 2 43774039-43810010 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062905 Approved Approved Cytosol Expressed in all fallopian tube: 85.4 -LHCGR HHG, LCGR, LGR2, LHR, ULG5 ENSG00000138039 Luteinizing hormone/choriogonadotropin receptor 2 48686775-48755730 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009814 Uncertain Group enriched 5 adipose tissue: 1.3;adrenal gland: 1.1;ovary: 1.5;testis: 4.3;thyroid gland: 1.1 breast: 0.3 -THUMPD2 C2orf8, MGC2454 ENSG00000138050 THUMP domain containing 2 2 39736060-39779267 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043042, HPA058025 Approved Uncertain Nucleoplasm Mixed ovary: 3.8 -CYP1B1 CP1B, GLC3A ENSG00000138061 Cytochrome P450, family 1, subfamily B, polypeptide 1 2 38066973-38109902 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011705, HPA026863 Approved Uncertain Mitochondria Mixed fallopian tube: 75.4 -SULT6B1 ENSG00000138068 Sulfotransferase family, cytosolic, 6B, member 1 2 37167820-37196598 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 4.3 fallopian tube: 0.9 -RAB1A RAB1, YPT1 ENSG00000138069 RAB1A, member RAS oncogene family 2 65070701-65130106 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005331, HPA056141 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all thyroid gland: 217.2 -ACTR2 ARP2 ENSG00000138071 ARP2 actin-related protein 2 homolog (yeast) 2 65227753-65271253 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005083, HPA015050 Approved Approved Cytosol Expressed in all appendix: 300.7 -PREB SEC12 ENSG00000138073 Prolactin regulatory element binding 2 27130756-27134675 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013582, HPA014133 Uncertain Approved Endoplasmic reticulum Expressed in all epididymis: 106.0 -SLC5A6 SMVT ENSG00000138074 Solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2 27199587-27212958 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036958 Approved Approved Cell Junctions Expressed in all epididymis: 82.1 -ABCG5 STSL ENSG00000138075 ATP-binding cassette, sub-family G (WHITE), member 5 2 43812472-43838865 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA016514 Approved Approved Nucleus Group enriched 32 duodenum: 58.0;liver: 28.3;small intestine: 57.4 gallbladder: 1.4 -PREPL KIAA0436 ENSG00000138078 Prolyl endopeptidase-like 2 44316281-44361862 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063238 Approved Expressed in all cerebral cortex: 258.1 -SLC3A1 ATR1, CSNU1, D2H, NBAT, RBAT ENSG00000138079 Solute carrier family 3 (amino acid transporter heavy chain), member 1 2 44275458-44321494 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038360 Supported Tissue enhanced 0 kidney: 649.8 small intestine: 151.9 -EMILIN1 DKFZp586M121, gp115 ENSG00000138080 Elastin microfibril interfacer 1 2 27078567-27086408 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA002822 Supported Expressed in all seminal vesicle: 73.3 -FBXO11 FBX11, UBR6 ENSG00000138081 F-box protein 11 2 47789316-47905793 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002690 Uncertain Supported Nucleus Expressed in all testis: 74.9 -SIX3 HPE2 ENSG00000138083 SIX homeobox 3 2 44941898-44946077 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA067988 Approved Nucleoplasm Tissue enriched 30 parathyroid gland: 38.9 cervix: 1.2 -ATRAID APR3, C2orf28, HSPC013, p18 ENSG00000138085 All-trans retinoic acid-induced differentiation factor 2 27212027-27217178 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051353 Uncertain Expressed in all epididymis: 511.9 -CENPO CENP-O, MGC11266 ENSG00000138092 Centromere protein O 2 24793136-24822376 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046189 Supported Nucleus Mixed testis: 13.0 -LRPPRC GP130, LRP130, LSFC ENSG00000138095 Leucine-rich pentatricopeptide repeat containing 2 43886508-43996005 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033786, HPA036408, HPA036409 Supported Validated Mitochondria Expressed in all parathyroid gland: 78.8 -TRIM54 MURF, MURF-3, RNF30 ENSG00000138100 Tripartite motif containing 54 2 27282392-27307439 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019690 Uncertain Tissue enhanced 0 heart muscle: 60.8;skeletal muscle: 181.1 epididymis: 30.3 -DTNB ENSG00000138101 Dystrobrevin, beta 2 25377198-25673647 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061357 Uncertain Approved Mitochondria Mixed cerebral cortex: 23.9 -ACTR1A ARP1, Arp1A ENSG00000138107 ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 10 102479229-102502711 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037193, HPA047443 Approved Approved Microtubules Expressed in all cerebral cortex: 114.7 -CYP2C9 CYP2C10, P450IIC9 ENSG00000138109 Cytochrome P450, family 2, subfamily C, polypeptide 9 10 94938658-94989390 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015066, CAB016123 Supported Tissue enriched 7 liver: 959.9 duodenum: 140.6 -TMEM180 bA18I14.8, C10orf77, FLJ22529 ENSG00000138111 Transmembrane protein 180 10 102461395-102477045 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA018031 Uncertain Approved Golgi apparatus
Cytosol Mixed skin: 8.8 -CYP2C8 CPC8 ENSG00000138115 Cytochrome P450, family 2, subfamily C, polypeptide 8 10 95036772-95069497 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013547, HPA013970, HPA015066 Supported Tissue enriched 152 liver: 1121.7 gallbladder: 7.3 -MYOF FER1L3, KIAA1207 ENSG00000138119 Myoferlin 10 93306429-93482317 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014245 Approved Supported Vesicles
Plasma membrane Mixed cervix: 100.7 -LOXL4 FLJ21889, LOXC ENSG00000138131 Lysyl oxidase-like 4 10 98247690-98268250 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033876, HPA037609 Approved Approved Vesicles Mixed cervix: 17.7 -STAMBPL1 ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, FLJ31524, KIAA1373 ENSG00000138134 STAM binding protein-like 1 10 88879734-88975153 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040202 Uncertain Approved Plasma membrane Mixed testis: 29.8 -CH25H ENSG00000138135 Cholesterol 25-hydroxylase 10 89205629-89207314 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed gallbladder: 23.0 -LBX1 HPX6, LBX1H ENSG00000138136 Ladybird homeobox 1 10 101226195-101229794 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA002016, HPA002086 Uncertain Approved Nucleoplasm
Nuclear bodies Tissue enriched 65 skeletal muscle: 9.1 lung: 0.1 -ATAD1 FLJ14600 ENSG00000138138 ATPase family, AAA domain containing 1 10 87751512-87841343 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037569 Uncertain Approved Nucleus
Nucleoli
Mitochondria Expressed in all parathyroid gland: 28.5 -BTBD16 C10orf87, Em:AC061711.1, FLJ25359 ENSG00000138152 BTB (POZ) domain containing 16 10 122271306-122338162 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040529, HPA057638 Uncertain Uncertain Nucleoli
Cytosol Group enriched 7 skin: 9.9;testis: 14.1;urinary bladder: 19.7 liver: 2.1 -KIF11 Eg5, HKSP, KNSL1, TRIP5 ENSG00000138160 Kinesin family member 11 10 92593286-92655395 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006916, HPA010093, HPA010568, CAB017617 Supported Supported Cytosol Mixed testis: 21.8 -CUZD1 ERG-1, UO-44 ENSG00000138161 CUB and zona pellucida-like domains 1 10 122832149-122850793 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA068479, HPA068660, HPA074117 Supported Approved Nucleoli
Vesicles Tissue enriched 170 pancreas: 380.4 testis: 2.2 -TACC2 AZU-1 ENSG00000138162 Transforming, acidic coiled-coil containing protein 2 10 121989174-122254545 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031020, HPA031021, HPA061394 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Mixed skeletal muscle: 112.7 -DUSP5 HVH3 ENSG00000138166 Dual specificity phosphatase 5 10 110497838-110511544 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed esophagus: 100.5 -CALHM2 FAM26B ENSG00000138172 Calcium homeostasis modulator 2 10 103446786-103452402 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014706 Approved Approved Nucleoplasm
Mitochondria
Cytosol Mixed ovary: 44.9 -ARL3 ARFL3 ENSG00000138175 ADP-ribosylation factor-like 3 10 102673731-102714407 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036292, HPA063596 Approved Supported Nucleus
Centrosome Expressed in all cerebral cortex: 35.9 -CEP55 C10orf3, CT111, FLJ10540 ENSG00000138180 Centrosomal protein 55kDa 10 93496632-93529092 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023430 Approved Supported Plasma membrane
Microtubule organizing center Tissue enhanced 0 testis: 39.1 lymph node: 17.8 -KIF20B CT90, KRMP1, MPHOSPH1, MPP1 ENSG00000138182 Kinesin family member 20B 10 89701610-89774939 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031263, HPA050214 Uncertain Validated Nucleoplasm
Midbody
Cytosol Mixed testis: 12.8 -ENTPD1 ATPDase, CD39, NTPDase-1, SPG64 ENSG00000138185 Ectonucleoside triphosphate diphosphohydrolase 1 10 95711779-95869695 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002494, HPA014067 Supported Uncertain Microtubules Mixed smooth muscle: 89.5 -EXOC6 DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, SEC15L, SEC15L1, Sec15p ENSG00000138190 Exocyst complex component 6 10 92834713-93059493 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036285, HPA059111 Approved Supported Nucleoplasm
Vesicles Expressed in all placenta: 49.2 -PLCE1 KIAA1516, NPHS3, PLCE ENSG00000138193 Phospholipase C, epsilon 1 10 93993989-94332823 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015597, HPA015598 Approved Supported Cytosol Mixed endometrium: 21.7 -RBP4 ENSG00000138207 Retinol binding protein 4, plasma 10 93591687-93601744 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001641, CAB004555 Supported Tissue enriched 10 liver: 6086.1 adipose tissue: 630.4 -DBR1 ENSG00000138231 Debranching RNA lariats 1 3 138161012-138174949 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035365 Supported Supported Nucleoplasm Expressed in all thyroid gland: 13.8 -DNAJC13 KIAA0678, RME8 ENSG00000138246 DnaJ (Hsp40) homolog, subfamily C, member 13 3 132417526-132539032 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036923, HPA036924 Approved Supported Vesicles
Cytosol Expressed in all thyroid gland: 28.8 -GPR87 GPR95 ENSG00000138271 G protein-coupled receptor 87 3 151294086-151316952 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA066313 Approved Nucleoplasm
Lipid droplets
Mitochondria Tissue enhanced 0 esophagus: 29.4;skin: 29.8 placenta: 11.9 -ANXA7 ANX7 ENSG00000138279 Annexin A7 10 73375101-73414076 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004312, HPA064290 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 464.4 -FAM149B1 KIAA0974 ENSG00000138286 Family with sequence similarity 149, member B1 10 73168166-73244504 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039189, HPA039859 Uncertain Approved Nucleoplasm Expressed in all testis: 38.1 -ASCC1 ASC1p50, CGI-18, Em:AC022392.3 ENSG00000138303 Activating signal cointegrator 1 complex subunit 1 10 72096032-72217134 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038038, HPA057567 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 46.1 -PLA2G12B PLA2G13 ENSG00000138308 Phospholipase A2, group XIIB 10 72935170-72954778 Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057745, HPA059562 Approved Approved Vesicles Group enriched 10 duodenum: 36.2;kidney: 18.9;liver: 49.8;small intestine: 46.9 lung: 3.9 -ZNF365 KIAA0844, UAN ENSG00000138311 Zinc finger protein 365 10 62374192-62672011 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052446 Approved Supported Vesicles
Microtubule organizing center Tissue enriched 5 cerebral cortex: 54.6 parathyroid gland: 10.7 -OIT3 FLJ39116, LZP ENSG00000138315 Oncoprotein induced transcript 3 10 72893581-72933033 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 9 liver: 56.5 spleen: 6.6 -ADAMTS14 ENSG00000138316 ADAM metallopeptidase with thrombospondin type 1 motif, 14 10 70672803-70762441 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA034605 Uncertain Cytosol Tissue enhanced 0 gallbladder: 10.9;placenta: 11.0 urinary bladder: 4.5 -RPS24 S24 ENSG00000138326 Ribosomal protein S24 10 78033760-78056812 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003364 Approved Approved Nuclear bodies
Endoplasmic reticulum
Cytosol Expressed in all ovary: 6812.2 -TET1 bA119F7.1, CXXC6, KIAA1676, LCX ENSG00000138336 Tet methylcytosine dioxygenase 1 10 68560656-68694482 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB014886, HPA019032, HPA057273 Approved Supported Nucleus
Nuclear membrane Mixed parathyroid gland: 2.4 -DNA2 DNA2L, KIAA0083 ENSG00000138346 DNA replication helicase/nuclease 2 10 68414064-68472121 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037487, HPA057526 Approved Supported Mitochondria Mixed lymph node: 6.3 -MYPN MYOP ENSG00000138347 Myopalladin 10 68106117-68212017 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036299, HPA061494 Supported Approved Nucleus
Vesicles
Cytosol Group enriched 29 heart muscle: 42.1;skeletal muscle: 99.9 esophagus: 2.4 -AOX1 AO, AOH1 ENSG00000138356 Aldehyde oxidase 1 2 200585868-200677064 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040199, HPA040215 Approved Supported Nuclear bodies
Cytosol Group enriched 5 adrenal gland: 370.6;kidney: 96.7;liver: 432.0 ovary: 56.6 -ATIC AICARFT, IMPCHASE, PURH ENSG00000138363 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2 215311817-215349773 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013462, HPA021012 Supported Validated Plasma membrane
Cytosol Expressed in all rectum: 44.5 -SMARCAL1 HARP, HHARP ENSG00000138375 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2 216412414-216483053 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020337 Uncertain Supported Nucleoplasm Expressed in all ovary: 19.7 -BARD1 ENSG00000138376 BRCA1 associated RING domain 1 2 214725646-214809711 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034106, HPA035354, HPA044864 Supported Supported Nuclear speckles Mixed testis: 11.0 -STAT4 ENSG00000138378 Signal transducer and activator of transcription 4 2 191029576-191151596 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001860, CAB013108 Approved Tissue enhanced 0 testis: 50.3 spleen: 18.8 -MSTN GDF8 ENSG00000138379 Myostatin 2 190055697-190062729 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009963 Approved Tissue enhanced 0 skeletal muscle: 3.4 endometrium: 1.3 -CARF ALS2CR8, CaRF, FLJ21579, NYD-SP24 ENSG00000138380 Calcium responsive transcription factor 2 202912214-202987063 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034557 Approved Approved Nucleoli fibrillar center
Vesicles
Intermediate filaments
Cytosol Mixed testis: 37.0 -ASNSD1 FLJ20752, NBLA00058, NS3TP1 ENSG00000138381 Asparagine synthetase domain containing 1 2 189661385-189670831 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036132, HPA036133, HPA075042 Uncertain Approved Cytosol Expressed in all placenta: 50.9 -METTL5 HSPC133 ENSG00000138382 Methyltransferase like 5 2 169810081-169824931 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038223 Uncertain Approved Nucleoli
Cytosol Expressed in all epididymis: 75.3 -SSB La, La/SSB, LARP3 ENSG00000138385 Sjogren syndrome antigen B (autoantigen La) 2 169791933-169812064 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004643, HPA017287 Supported Approved Nucleoplasm Expressed in all thyroid gland: 130.8 -NAB1 ENSG00000138386 NGFI-A binding protein 1 (EGR1 binding protein 1) 2 190646746-190692766 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002738 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Expressed in all skin: 80.7 -CDK15 ALS2CR7, PFTAIRE2, PFTK2 ENSG00000138395 Cyclin-dependent kinase 15 2 201790461-201895550 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA015786 Uncertain Approved Nucleus
Golgi apparatus Tissue enhanced 0 epididymis: 20.9;ovary: 8.4 testis: 4.0 -PPIG CARS-Cyp, SCAF10, SRCyp ENSG00000138398 Peptidylprolyl isomerase G (cyclophilin G) 2 169584340-169641406 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021788, HPA057469 Supported Supported Nuclear speckles
Cytosol Expressed in all parathyroid gland: 85.0 -FASTKD1 FLJ21901 ENSG00000138399 FAST kinase domains 1 2 169529749-169573875 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043719 Approved Approved Nucleoplasm Expressed in all rectum: 27.1 -MDH1B FLJ25341, RP11-95H11 ENSG00000138400 Malate dehydrogenase 1B, NAD (soluble) 2 206737763-206765547 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA034741 Uncertain Group enriched 5 fallopian tube: 34.9;testis: 43.5 parathyroid gland: 7.4 -HECW2 KIAA1301, NEDL2 ENSG00000138411 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 2 196194370-196593692 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034609 Uncertain Approved Nucleoli fibrillar center
Endoplasmic reticulum Mixed placenta: 15.7 -IDH1 ENSG00000138413 Isocitrate dehydrogenase 1 (NADP+), soluble 2 208236227-208266074 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033218, HPA035248, HPA057936, CAB062556 Supported Approved Nuclear bodies
Cytosol Expressed in all prostate: 359.5 -OLA1 GTPBP9, PTD004 ENSG00000138430 Obg-like ATPase 1 2 174072447-174248698 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035790, HPA041443 Approved Validated Cytosol Expressed in all cerebral cortex: 99.9 -CIR1 CIR ENSG00000138433 Corepressor interacting with RBPJ, 1 2 174348022-174395715 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015784 Supported Nuclear speckles Expressed in all testis: 57.0 -SSFA2 CS-1, KIAA1927, KRAP, SPAG13 ENSG00000138434 Sperm specific antigen 2 2 181891833-181930738 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034665, HPA039989 Uncertain Supported Nucleus
Plasma membrane
Cytosol Expressed in all skin: 137.4 -CHRNA1 CHRNA ENSG00000138435 Cholinergic receptor, nicotinic, alpha 1 (muscle) 2 174747592-174764472 Disease related genes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA071554 Supported Plasma membrane Tissue enhanced 0 skeletal muscle: 7.2 prostate: 2.6 -FAM117B ALS2CR13, FLJ38771 ENSG00000138439 Family with sequence similarity 117, member B 2 202635188-202769757 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003229, HPA028746 Uncertain Approved Nucleus
Centrosome Mixed parathyroid gland: 24.1 -WDR12 FLJ10881, YTM1 ENSG00000138442 WD repeat domain 12 2 202874782-203014798 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036389 Uncertain Approved Nucleoli
Plasma membrane
Cytosol Mixed testis: 7.3 -ABI2 ABI-2, ABI2B, AblBP3, AIP-1, argBPIA, SSH3BP2 ENSG00000138443 Abl-interactor 2 2 203328219-203447723 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062433, HPA070567 Supported Approved Nucleoplasm Expressed in all cerebral cortex: 99.1 -ITGAV CD51, MSK8, VNRA, VTNR ENSG00000138448 Integrin, alpha V 2 186590065-186680901 Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002499, HPA004856 Supported Approved Focal adhesion sites
Cytosol Expressed in all parathyroid gland: 187.7 -SLC40A1 FPN1, HFE4, IREG1, MTP1, SLC11A3 ENSG00000138449 Solute carrier family 40 (iron-regulated transporter), member 1 2 189560579-189583758 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065634 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all spleen: 496.0 -SLC35A5 FLJ20730 ENSG00000138459 Solute carrier family 35, member A5 3 112561709-112585577 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035519, HPA057964 Uncertain Approved Golgi apparatus Expressed in all thyroid gland: 43.7 -DIRC2 FLJ14784, RCC4 ENSG00000138463 Disrupted in renal carcinoma 2 3 122794795-122881139 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072579 Supported Vesicles Expressed in all parathyroid gland: 15.9 -SENP7 ENSG00000138468 SUMO1/sentrin specific peptidase 7 3 101324205-101513241 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027259 Approved Approved Nucleoplasm
Cytosol Expressed in all endometrium: 44.0 -GUCA1C GCAP3 ENSG00000138472 Guanylate cyclase activator 1C 3 108907792-108953895 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041597 Approved Group enriched 8 heart muscle: 7.1;pancreas: 8.4;stomach: 5.1;testis: 1.7 kidney: 0.7 -CCDC54 FLJ25362, NYD-SP17, SP17 ENSG00000138483 Coiled-coil domain containing 54 3 107377194-107378637 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 51 testis: 165.3 epididymis: 3.2 -COX17 ENSG00000138495 COX17 cytochrome c oxidase copper chaperone 3 119654513-119677454 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042226, HPA048158 Supported Supported Mitochondria Expressed in all adrenal gland: 115.3 -PARP9 BAL, BAL1 ENSG00000138496 Poly (ADP-ribose) polymerase family, member 9 3 122527924-122564577 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066708 Supported Nucleoplasm
Mitochondria
Cytosol Expressed in all spleen: 61.9 -MNS1 FLJ11222, SPATA40 ENSG00000138587 Meiosis-specific nuclear structural 1 15 56421544-56465137 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039975, HPA040382 Uncertain Approved Nucleoplasm
Nuclear speckles Group enriched 6 fallopian tube: 34.8;testis: 86.8 kidney: 10.0 -USP8 HumORF8, KIAA0055, SPG59, UBPY ENSG00000138592 Ubiquitin specific peptidase 8 15 50424380-50514419 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004869, HPA050215 Uncertain Supported Golgi apparatus
Cytosol Expressed in all parathyroid gland: 75.8 -SECISBP2L KIAA0256 ENSG00000138593 SECIS binding protein 2-like 15 48988476-49046563 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039875 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 83.3 -TMOD3 UTMOD ENSG00000138594 Tropomodulin 3 (ubiquitous) 15 51829628-51947295 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001849 Approved Approved Actin filaments
Cytosol Expressed in all esophagus: 86.7 -SPPL2A IMP3, PSL2 ENSG00000138600 Signal peptide peptidase like 2A 15 50702266-50765808 Enzymes, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036062, HPA067304 Supported Supported Vesicles Expressed in all parathyroid gland: 285.5 -GLCE HSEPI, KIAA0836 ENSG00000138604 Glucuronic acid epimerase 15 69160584-69272217 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040481, HPA048216 Uncertain Approved Mitochondria Mixed placenta: 18.9 -SHF ENSG00000138606 Src homology 2 domain containing F 15 45167214-45201175 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA057381 Approved Nucleus Mixed adrenal gland: 30.1 -APH1B APH-1B, DKFZp564D0372, PSFL ENSG00000138613 APH1B gamma secretase subunit 15 63276018-63309126 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 testis: 153.1 thyroid gland: 32.0 -VWA9 C15orf44, DKFZP564O1664 ENSG00000138614 Von Willebrand factor A domain containing 9 15 65578753-65611289 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040255, HPA040651 Approved Approved Nucleoplasm
Nuclear membrane
Nuclear bodies
Mitochondria Expressed in all fallopian tube: 38.7 -CILP HsT18872 ENSG00000138615 Cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 15 65194758-65211488 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003195 Uncertain Tissue enhanced 0 cervix, uterine: 66.6;smooth muscle: 69.9 gallbladder: 55.4 -PARP16 C15orf30, FLJ20509, FLJ25281, pART15 ENSG00000138617 Poly (ADP-ribose) polymerase family, member 16 15 65234460-65300618 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017081 Approved Expressed in all ovary: 13.0 -PPCDC FLJ14585, MDS018 ENSG00000138621 Phosphopantothenoylcysteine decarboxylase 15 75023555-75117462 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045667 Approved Approved Cytosol Expressed in all parathyroid gland: 21.9 -HCN4 ENSG00000138622 Hyperpolarization activated cyclic nucleotide gated potassium channel 4 15 73319859-73369264 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 cerebral cortex: 1.4;heart muscle: 1.9;testis: 6.7 adrenal gland: 0.5 -SEMA7A CD108, H-Sema-L, SEMAL ENSG00000138623 Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 15 74409289-74434467 Blood group antigen proteins, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008210, HPA042273 Uncertain Uncertain Vesicles Tissue enhanced 0 spleen: 60.5;testis: 57.0 placenta: 44.5 -UBL7 BMSC-UbP, MGC14421 ENSG00000138629 Ubiquitin-like 7 15 74445977-74461182 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040423, HPA041897 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 75.0 -ARHGAP24 DKFZP564B1162, FilGAP, FLJ33877 ENSG00000138639 Rho GTPase activating protein 24 4 85475114-86002670 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014288 Approved Approved Plasma membrane
Cytosol Expressed in all kidney: 105.5 -FAM13A ARHGAP48, FAM13A1, KIAA0914 ENSG00000138640 Family with sequence similarity 13, member A 4 88725955-89111398 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038108, HPA038109 Uncertain Approved Nucleoli
Cell Junctions
Cytosol Expressed in all parathyroid gland: 113.3 -HERC3 KIAA0032 ENSG00000138641 HECT and RLD domain containing E3 ubiquitin protein ligase 3 4 88521048-88708542 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039170 Approved Approved Cytosol Expressed in all parathyroid gland: 59.9 -HERC6 FLJ20637 ENSG00000138642 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4 88378739-88443111 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035846 Uncertain Supported Nucleus
Cytosol Expressed in all esophagus: 22.9 -HERC5 CEB1 ENSG00000138646 HECT and RLD domain containing E3 ubiquitin protein ligase 5 4 88457117-88506163 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043929 Supported Tissue enhanced 0 testis: 106.1 endometrium: 25.8 -PCDH10 KIAA1400, OL-PCDH ENSG00000138650 Protocadherin 10 4 133149315-133208606 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011220, HPA073462 Approved Approved Nucleus
Golgi apparatus
Vesicles Group enriched 5 cerebral cortex: 62.2;placenta: 36.4;prostate: 17.0;seminal vesicle: 24.4 adrenal gland: 6.9 -NDST4 ENSG00000138653 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 4 114827763-115113876 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA011129 Uncertain Tissue enhanced 0 cerebral cortex: 1.4;ovary: 1.8 spleen: 1.0 -ZGRF1 C4orf21, FLJ11331 ENSG00000138658 Zinc finger, GRF-type containing 1 4 112539333-112636995 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030704, HPA030706 Uncertain Approved Cytosol Mixed testis: 6.7 -AP1AR 2C18, C4orf16, gamma-BAR, PRO0971 ENSG00000138660 Adaptor-related protein complex 1 associated regulatory protein 4 112231737-112270047 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035863, HPA058115 Approved Supported Golgi apparatus Expressed in all parathyroid gland: 56.9 -COPS4 CSN4 ENSG00000138663 COP9 signalosome subunit 4 4 83034447-83075818 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036894, HPA042828 Uncertain Supported Nuclear speckles Expressed in all testis: 78.6 -HNRNPD AUF1, HNRPD ENSG00000138668 Heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 4 82352498-82374503 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004911 Supported Validated Nucleoplasm Expressed in all lymph node: 345.7 -PRKG2 cGKII, PRKGR2 ENSG00000138669 Protein kinase, cGMP-dependent, type II 4 81087370-81215117 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007386, CAB018739 Approved Tissue enhanced 0 prostate: 14.7;small intestine: 14.7 duodenum: 10.0 -RASGEF1B FLJ31695, GPIG4 ENSG00000138670 RasGEF domain family, member 1B 4 81426393-82044244 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044574 Uncertain Approved Nucleus Mixed skin: 31.8 -SEC31A ABP125, ABP130, KIAA0905, SEC31L1 ENSG00000138674 SEC31 homolog A, COPII coat complex component 4 82818661-82901166 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005457 Approved Supported Vesicles
Cytosol Expressed in all thyroid gland: 279.9 -FGF5 ENSG00000138675 Fibroblast growth factor 5 4 80266599-80336680 Disease related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010313, HPA042442 Supported Nucleus
Nucleoli fibrillar center
Cytosol Tissue enhanced 0 gallbladder: 5.6 smooth muscle: 1.4 -GPAT3 AGPAT10, AGPAT9, HMFN0839, LPAAT-theta, MAG1, MGC11324 ENSG00000138678 Glycerol-3-phosphate acyltransferase 3 4 83535914-83605875 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029414, CAB033749 Approved Uncertain Plasma membrane
Cytosol Tissue enhanced 0 kidney: 89.3 duodenum: 41.9 -IL21 IL-21, Za11 ENSG00000138684 Interleukin 21 4 122612628-122621069 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 18.3;testis: 6.4;tonsil: 8.5 appendix: 2.7 -FGF2 FGFB ENSG00000138685 Fibroblast growth factor 2 (basic) 4 122826708-122898236 Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000125 Approved Supported Nucleoplasm
Nuclear bodies Mixed adipose tissue: 25.4 -BBS7 BBS2L1, FLJ10715 ENSG00000138686 Bardet-Biedl syndrome 7 4 121824440-121870497 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044592 Approved Mixed cerebral cortex: 25.7 -KIAA1109 FLJ21404, FSA, KIAA1371, Tweek ENSG00000138688 KIAA1109 4 122152333-122362758 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038076 Approved Approved Nucleoplasm
Centrosome Expressed in all parathyroid gland: 128.4 -BMPR1B ALK6, CDw293 ENSG00000138696 Bone morphogenetic protein receptor, type IB 4 94757968-95158448 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB009634 Uncertain Tissue enhanced 0 cervix, uterine: 37.0;prostate: 36.4 seminal vesicle: 20.8 -RAP1GDS1 SmgGDS ENSG00000138698 RAP1, GTP-GDP dissociation stimulator 1 4 98261384-98443861 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019060 Approved Supported Cytosol Expressed in all cerebral cortex: 94.1 -LARP1B DKFZp434K245, DKFZp686E0316, FLJ10378, LARP2 ENSG00000138709 La ribonucleoprotein domain family, member 1B 4 128061268-128222931 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036280, HPA036281 Approved Supported Nuclear bodies
Cytosol Expressed in all testis: 102.5 -MMRN1 ECM, EMILIN4, GPIa*, MMRN ENSG00000138722 Multimerin 1 4 89879532-89954629 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035769 Supported Approved Endoplasmic reticulum Mixed placenta: 57.0 -PDE5A ENSG00000138735 Phosphodiesterase 5A, cGMP-specific 4 119494395-119628991 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004729, HPA012873 Approved Approved Cytosol Expressed in all prostate: 90.8 -PRDM5 PFM2 ENSG00000138738 PR domain containing 5 4 120684919-120922870 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA051406 Supported Supported Nucleus
Nucleoli
Nuclear bodies Mixed parathyroid gland: 20.6 -TRPC3 ENSG00000138741 Transient receptor potential cation channel, subfamily C, member 3 4 121879027-121951754 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA037969 Uncertain Tissue enhanced 0 smooth muscle: 4.1 cerebral cortex: 2.1 -NAAA ASAHL ENSG00000138744 N-acylethanolamine acid amidase 4 75913657-75941051 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB026135 Approved Expressed in all prostate: 112.5 -NUP54 ENSG00000138750 Nucleoporin 54kDa 4 76114659-76148515 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035929, HPA058122 Approved Approved Nucleoplasm Expressed in all testis: 38.9 -CXCL9 CMK, crg-10, Humig, MIG, SCYB9 ENSG00000138755 Chemokine (C-X-C motif) ligand 9 4 76001275-76007488 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 332.0 appendix: 89.3 -BMP2K BIKe, DKFZp434K0614 ENSG00000138756 BMP2 inducible kinase 4 78776342-78916372 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026436, HPA026451, HPA026501 Approved Supported Nuclear speckles Mixed testis: 32.3 -G3BP2 KIAA0660 ENSG00000138757 GTPase activating protein (SH3 domain) binding protein 2 4 75642782-75724525 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018304, HPA018425 Supported Validated Cytosol Expressed in all cerebral cortex: 179.1 -SEPT11 FLJ10849 ENSG00000138758 Septin 11 4 76949703-77040384 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003459, HPA005665 Approved Expressed in all placenta: 119.4 -FRAS1 FLJ14927, FLJ22031, KIAA1500 ENSG00000138759 Fraser extracellular matrix complex subunit 1 4 78057570-78544269 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011281, HPA051601 Approved Approved Nucleoli fibrillar center Tissue enhanced 0 thyroid gland: 20.2 placenta: 8.2 -SCARB2 CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII ENSG00000138760 Scavenger receptor class B, member 2 4 76158737-76213893 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015415, HPA018014 Supported Approved Cytosol Expressed in all cerebral cortex: 180.4 -CCNG2 ENSG00000138764 Cyclin G2 4 77157151-77433388 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA034684 Approved Approved Nucleoplasm
Cytosol Expressed in all esophagus: 151.2 -CNOT6L Ccr4b, DKFZp434K098 ENSG00000138767 CCR4-NOT transcription complex, subunit 6-like 4 77713387-77819615 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042688 Uncertain Supported Cytosol Expressed in all lymph node: 44.2 -USO1 p115, TAP, VDP ENSG00000138768 USO1 vesicle transport factor 4 75724593-75814286 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010108, HPA038282, HPA038283 Supported Validated Nucleoli fibrillar center
Golgi apparatus Expressed in all thyroid gland: 90.8 -CDKL2 KKIAMRE, P56 ENSG00000138769 Cyclin-dependent kinase-like 2 (CDC2-related kinase) 4 75578005-75630716 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040672 Uncertain Approved Nucleus
Centrosome Tissue enhanced 0 testis: 32.9 cerebral cortex: 9.8 -SHROOM3 APXL3, KIAA1481, SHRM, ShrmL ENSG00000138771 Shroom family member 3 4 76435100-76783253 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047784 Supported Mixed parathyroid gland: 27.2 -ANXA3 ANX3 ENSG00000138772 Annexin A3 4 78551519-78610451 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013398, HPA013431 Supported Supported Cytosol Expressed in all bone marrow: 198.6 -PPA2 FLJ20459 ENSG00000138777 Pyrophosphatase (inorganic) 2 4 105369077-105474081 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030888, HPA031671, HPA031672 Supported Approved Nucleus
Mitochondria Expressed in all kidney: 21.6 -CENPE KIF10, PPP1R61 ENSG00000138778 Centromere protein E, 312kDa 4 103105806-103198409 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042294 Approved Supported Microtubules
Cytosol Mixed testis: 7.7 -GSTCD FLJ13273 ENSG00000138780 Glutathione S-transferase, C-terminal domain containing 4 105708778-105847728 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046160, HPA061782 Approved Supported Nucleus Mixed testis: 18.8 -INTS12 INT12, PHF22, SBBI22 ENSG00000138785 Integrator complex subunit 12 4 105682627-105895986 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035772, HPA041814 Approved Approved Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Expressed in all thyroid gland: 33.5 -ENPEP CD249, gp160 ENSG00000138792 Glutamyl aminopeptidase (aminopeptidase A) 4 110365733-110565285 CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005128 Approved Group enriched 5 duodenum: 37.5;kidney: 93.6;parathyroid gland: 157.9;small intestine: 183.8 placenta: 21.5 -CASP6 MCH2 ENSG00000138794 Caspase 6, apoptosis-related cysteine peptidase 4 109688622-109703583 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003775, HPA011337, HPA024303 Supported Supported Nucleus
Cytosol Expressed in all small intestine: 47.1 -LEF1 TCF10, TCF1ALPHA, TCF7L3 ENSG00000138795 Lymphoid enhancer-binding factor 1 4 108047545-108168956 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002087, CAB019405 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Tissue enhanced 0 lymph node: 42.2 tonsil: 29.3 -HADH HADH1, HADHSC, SCHAD ENSG00000138796 Hydroxyacyl-CoA dehydrogenase 4 107989714-108035175 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039588, HPA043888 Supported Supported Mitochondria Expressed in all kidney: 188.7 -EGF ENSG00000138798 Epidermal growth factor 4 109912884-110012266 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 kidney: 121.1 pancreas: 18.5 -PAPSS1 ATPSK1, PAPSS ENSG00000138801 3'-phosphoadenosine 5'-phosphosulfate synthase 1 4 107590276-107720452 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049781 Approved Approved Nucleus
Nucleoli Expressed in all endometrium: 73.3 -SEC24B ENSG00000138802 SEC24 homolog B, COPII coat complex component 4 109433772-109540896 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038181 Approved Approved Nucleus
Vesicles Expressed in all parathyroid gland: 42.0 -C4orf17 DKFZP434G072 ENSG00000138813 Chromosome 4 open reading frame 17 4 99511004-99542303 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA060374, HPA060564 Uncertain Tissue enriched 341 testis: 34.0 epididymis: 0.0 -PPP3CA CALN, CALNA, CNA1, PPP2B ENSG00000138814 Protein phosphatase 3, catalytic subunit, alpha isozyme 4 101023409-101348278 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012778, CAB018581 Supported Validated Nucleoplasm
Cytosol Expressed in all cerebral cortex: 164.8 -SLC39A8 BIGM103 ENSG00000138821 Solute carrier family 39 (zinc transporter), member 8 4 102251041-102431258 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA038832, HPA038833 Approved Tissue enhanced 0 lung: 257.1 cervix: 128.6 -MTTP ABL, MTP ENSG00000138823 Microsomal triglyceride transfer protein 4 99563761-99623999 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051170, HPA054862 Uncertain Approved Cytosol Group enriched 17 duodenum: 243.0;liver: 133.9;small intestine: 299.0 testis: 13.5 -FBN2 CCA, DA9 ENSG00000138829 Fibrillin 2 5 128257909-128659185 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012853, CAB026401 Supported Approved Nucleoplasm
Cytosol Tissue enriched 8 placenta: 117.6 testis: 13.8 -MAPK8IP3 JIP3, JSAP1, KIAA1066, syd ENSG00000138834 Mitogen-activated protein kinase 8 interacting protein 3 16 1706183-1770317 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005580, HPA041785, HPA069311 Approved Approved Vesicles Expressed in all cerebral cortex: 84.1 -RGS3 C2PA, FLJ20370, PDZ-RGS3 ENSG00000138835 Regulator of G-protein signaling 3 9 113444731-113597743 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032507, HPA041109 Validated Nucleoplasm
Mitochondria
Cytosol Expressed in all gallbladder: 66.7 -GUCD1 C22orf13, LLN4, MGC1842 ENSG00000138867 Guanylyl cyclase domain containing 1 22 24540423-24555935 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022786 Approved Nucleoplasm Expressed in all duodenum: 64.7 -TTLL8 ENSG00000138892 Tubulin tyrosine ligase-like family member 8 22 50015123-50056935 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA016882 Uncertain Tissue enriched 42 testis: 4.2 epididymis: 0.0 -RNF185 FLJ38628 ENSG00000138942 Ring finger protein 185 22 31160183-31207019 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 86.4 -KIAA1644 ENSG00000138944 KIAA1644 22 44243667-44312851 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051178 Uncertain Approved Vesicles
Cytosol Tissue enhanced 0 cerebral cortex: 27.6;endometrium: 42.5;smooth muscle: 44.0 cervix: 19.1 -PARVG ENSG00000138964 Parvin, gamma 22 44172956-44219533 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031833, HPA031834 Uncertain Tissue enhanced 0 spleen: 39.1 appendix: 36.8 -B4GALNT3 B4GalNac-T3, FLJ16224, FLJ40362 ENSG00000139044 Beta-1,4-N-acetyl-galactosaminyl transferase 3 12 460364-563509 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA011404 Approved Supported Golgi apparatus
Vesicles Tissue enhanced 0 stomach: 69.0 colon: 22.0 -PDE6H ENSG00000139053 Phosphodiesterase 6H, cGMP-specific, cone, gamma 12 14973022-14981865 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 bone marrow: 2.4;placenta: 1.2 adrenal gland: 0.5 -ERP27 C12orf46, ERp27, FLJ32115, PDIA8 ENSG00000139055 Endoplasmic reticulum protein 27 12 14914035-14939082 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039636, HPA052851 Supported Group enriched 9 fallopian tube: 103.3;pancreas: 282.2 urinary bladder: 20.3 -ETV6 TEL ENSG00000139083 Ets variant 6 12 11649854-11895402 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000264 Supported Validated Nucleoli
Cytosol Expressed in all bone marrow: 26.5 -GABARAPL1 APG8L, ATG8B, ATG8L, gec1 ENSG00000139112 GABA(A) receptor-associated protein like 1 12 10212458-10223130 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051386, HPA065883 Approved Approved Vesicles Expressed in all cerebral cortex: 433.4 -KIF21A FEOM1, FLJ20052 ENSG00000139116 Kinesin family member 21A 12 39293228-39443390 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022079, HPA058432 Approved Supported Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 79.6 fallopian tube: 59.5 -CPNE8 ENSG00000139117 Copine VIII 12 38646822-38907430 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038600 Approved Mixed placenta: 17.6 -YARS2 CGI-04, FLJ13995, mt-TyrRS ENSG00000139131 Tyrosyl-tRNA synthetase 2, mitochondrial 12 32727490-32755902 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038721, HPA057610, HPA074097 Uncertain Supported Nuclear bodies
Mitochondria Mixed placenta: 11.2 -FGD4 CMT4H, frabin, FRABP, ZFYVE6 ENSG00000139132 FYVE, RhoGEF and PH domain containing 4 12 32399529-32646050 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039235 Approved Supported Actin filaments Expressed in all ovary: 30.1 -ALG10 ALG10A, DIE2, FLJ14751 ENSG00000139133 ALG10, alpha-1,2-glucosyltransferase 12 34022281-34029694 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA043329, HPA063387 Approved Approved Endoplasmic reticulum Mixed parathyroid gland: 4.6 -PIK3C2G ENSG00000139144 Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 12 18247614-18648416 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 epididymis: 20.5;stomach: 19.7 parathyroid gland: 17.1 -FAM60A C12orf14, TERA ENSG00000139146 Family with sequence similarity 60, member A 12 31280584-31327058 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038167 Approved Nucleoplasm
Cytosol Mixed endometrium: 45.0 -PLCZ1 NYD-SP27, PLCzeta ENSG00000139151 Phospholipase C, zeta 1 12 18683169-18738057 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 22 testis: 48.2 skin: 2.1 -AEBP2 MGC17922 ENSG00000139154 AE binding protein 2 12 19404045-19720801 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020893, HPA022282 Uncertain Supported Nucleus Expressed in all placenta: 57.6 -SLCO1C1 OATP-F, OATP1, OATP1C1, SLC21A14 ENSG00000139155 Solute carrier organic anion transporter family, member 1C1 12 20695355-20753386 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 10 cerebral cortex: 27.6 testis: 2.6 -METTL20 C12orf72, DKFZp451L235, MGC50559 ENSG00000139160 Methyltransferase like 20 12 31647160-31673114 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039024 Uncertain Mixed parathyroid gland: 8.9 -ETNK1 EKI, EKI1 ENSG00000139163 Ethanolamine kinase 1 12 22625075-22690665 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010712, HPA029407 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all stomach: 45.8 -ZCRB1 MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19 ENSG00000139168 Zinc finger CCHC-type and RNA binding motif 1 12 42312078-42326118 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 153.1 -TMEM117 DKFZp434K2435 ENSG00000139173 Transmembrane protein 117 12 43835967-44389762 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046223 Uncertain Mixed seminal vesicle: 7.2 -PRICKLE1 EPM1B., FLJ31937, RILP ENSG00000139174 Prickle homolog 1 12 42456754-42590355 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001379, HPA050037 Approved Approved Nucleoplasm Mixed spleen: 24.0 -C1RL C1r-LP, C1RL1 ENSG00000139178 Complement component 1, r subcomponent-like 12 7089587-7109273 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011338, CAB026172 Supported Approved Microtubules
Cytosol Expressed in all liver: 83.7 -NDUFA9 CI-39k, NDUFS2L, SDR22E1 ENSG00000139180 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 12 4649095-4694317 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042268, HPA073212 Supported Supported Nucleoplasm
Mitochondria Expressed in all skeletal muscle: 38.4 -CLSTN3 CDHR14, CSTN3, KIAA0726 ENSG00000139182 Calsyntenin 3 12 7129698-7158945 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 127.1 parathyroid gland: 40.7 -KLRG1 2F1, CLEC15A, MAFA, MAFA-L ENSG00000139187 Killer cell lectin-like receptor subfamily G, member 1 12 8950044-9010760 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051403, HPA076494 Supported Vesicles Tissue enhanced 0 spleen: 16.1 lymph node: 13.8 -VAMP1 SYB1, VAMP-1 ENSG00000139190 Vesicle-associated membrane protein 1 (synaptobrevin 1) 12 6462237-6470987 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002779, CAB016119 Approved Mixed cerebral cortex: 43.6 -TAPBPL FLJ10143, TAPBP-R, TAPBPR ENSG00000139192 TAP binding protein-like 12 6451690-6466517 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039545 Uncertain Expressed in all thyroid gland: 39.0 -CD27 S152, TNFRSF7, Tp55 ENSG00000139193 CD27 molecule 12 6444867-6451718 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002420, HPA038936 Supported Tissue enhanced 0 lymph node: 142.5;tonsil: 90.3 spleen: 69.5 -RBP5 CRBPIII ENSG00000139194 Retinol binding protein 5, cellular 12 7123684-7128942 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038723 Approved Approved Golgi apparatus
Vesicles Tissue enhanced 0 kidney: 453.4;liver: 204.9 spleen: 105.3 -PEX5 PTS1R, PXR1 ENSG00000139197 Peroxisomal biogenesis factor 5 12 7188685-7218574 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039259, HPA039260 Supported Supported Golgi apparatus
Cytosol Expressed in all testis: 86.3 -PIANP C12orf53, DKFZp547D2210, PANP ENSG00000139200 PILR alpha associated neural protein 12 6693792-6700800 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA010631 Approved Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 64.5 endometrium: 13.5 -SLC38A4 ATA3, NAT3, PAAT ENSG00000139209 Solute carrier family 38, member 4 12 46764761-46832408 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 40 liver: 346.5 smooth muscle: 8.6 -AMIGO2 ALI1, DEGA ENSG00000139211 Adhesion molecule with Ig-like domain 2 12 47075707-47079951 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054004, HPA059601 Uncertain Approved Golgi apparatus
Plasma membrane
Cytosol Mixed smooth muscle: 54.4 -SCAF11 CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP ENSG00000139218 SR-related CTD-associated factor 11 12 45919131-45992120 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038862, HPA045456, HPA046345 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 85.0 -COL2A1 AOM, SEDC, STL1 ENSG00000139219 Collagen, type II, alpha 1 12 47972965-48004486 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002214, HPA055753 Supported Approved Nucleoplasm Group enriched 9 epididymis: 22.6;stomach: 6.0 testis: 1.6 -PPFIA2 ENSG00000139220 Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 12 81257975-81759553 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 5 cerebral cortex: 61.2 testis: 11.4 -ANP32D PP32R2 ENSG00000139223 Acidic (leucine-rich) nuclear phosphoprotein 32 family, member D 12 48472665-48473624 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA063133, HPA067561 Uncertain Approved Nucleoplasm
Centrosome
Cytosol Not detected thyroid gland: 0.1 -LLPH C12orf31, hLLP, MGC14817 ENSG00000139233 LLP homolog, long-term synaptic facilitation (Aplysia) 12 66116555-66130768 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048920, HPA058786 Validated Nucleoli Expressed in all adrenal gland: 42.7 -LRIG3 FLJ90440, KIAA3016 ENSG00000139263 Leucine-rich repeats and immunoglobulin-like domains 3 12 58872149-58920522 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA010773 Approved Approved Cytosol Tissue enhanced 0 thyroid gland: 97.1 skin: 33.1 -MARCH9 FLJ36578, RNF179 ENSG00000139266 Membrane-associated ring finger (C3HC4) 9 12 57755098-57760407 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all parathyroid gland: 29.7 -INHBE activin, MGC4638 ENSG00000139269 Inhibin, beta E 12 57452323-57459280 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016843, CAB034017 Supported Approved Vesicles Tissue enriched 28 liver: 68.1 thyroid gland: 2.4 -GLIPR1 GliPR, RTVP1 ENSG00000139278 GLI pathogenesis-related 1 12 75480680-75503853 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011014 Approved Mixed appendix: 66.6 -TPH2 FLJ37295, NTPH ENSG00000139287 Tryptophan hydroxylase 2 12 71938846-72186618 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB078198 Supported Tissue enhanced 0 cerebral cortex: 1.0 testis: 0.2 -PHLDA1 DT1P1B11, PHRIP, TDAG51 ENSG00000139289 Pleckstrin homology-like domain, family A, member 1 12 76025447-76033932 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016160, HPA019000, HPA063520 Approved Supported Nucleoli Mixed salivary gland: 69.1 -TMEM19 FLJ10936 ENSG00000139291 Transmembrane protein 19 12 71686087-71705046 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016830 Approved Expressed in all kidney: 40.5 -LGR5 FEX, GPR49, GPR67, HG38 ENSG00000139292 Leucine-rich repeat containing G protein-coupled receptor 5 12 71439770-71586310 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012530 Approved Tissue enhanced 0 fallopian tube: 26.3;placenta: 26.7 seminal vesicle: 9.7 -PTPRQ DFNB84 ENSG00000139304 Protein tyrosine phosphatase, receptor type, Q 12 80402178-80680234 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053245 Uncertain Approved Cytosol Tissue enhanced 0 testis: 4.8 lung: 3.4 -DUSP6 MKP-3, PYST1 ENSG00000139318 Dual specificity phosphatase 6 12 89347232-89353271 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017566, HPA053188 Approved Uncertain Nucleoplasm
Cytosol Expressed in all adipose tissue: 140.8 -POC1B FLJ14923, TUWD12, WDR51B ENSG00000139323 POC1 centriolar protein B 12 89419718-89526024 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038841 Approved Expressed in all fallopian tube: 19.7 -TMTC3 FLJ90492, SMILE ENSG00000139324 Transmembrane and tetratricopeptide repeat containing 3 12 88142296-88199887 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038550 Approved Approved Microtubules Mixed skin: 14.9 -LUM LDC, SLRR2D ENSG00000139329 Lumican 12 91102629-91111831 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 gallbladder: 932.2 placenta: 597.0 -KERA CNA2, SLRR2B ENSG00000139330 Keratocan 12 91050491-91057983 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039321 Uncertain Tissue enhanced 0 gallbladder: 1.5 breast: 0.8 -SNRPF Sm-F ENSG00000139343 Small nuclear ribonucleoprotein polypeptide F 12 95858928-95903828 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all appendix: 38.1 -AMDHD1 MGC35366 ENSG00000139344 Amidohydrolase domain containing 1 12 95943293-95968716 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039720 Approved Approved Plasma membrane
Actin filaments
Focal adhesion sites Tissue enhanced 0 testis: 27.1 liver: 22.4 -NEDD1 GCP-WD, TUBGCP7 ENSG00000139350 Neural precursor cell expressed, developmentally down-regulated 1 12 96907223-96953777 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038591 Approved Expressed in all testis: 42.6 -SYCP3 ENSG00000139351 Synaptonemal complex protein 3 12 101728648-101739472 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032978, HPA039635, HPA043938 Supported Tissue enriched 203 testis: 171.3 breast: 0.8 -ASCL1 ASH1, bHLHa46, HASH1 ENSG00000139352 Achaete-scute family bHLH transcription factor 1 12 102957686-102960516 Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA029217 Supported Group enriched 8 cerebral cortex: 16.3;liver: 6.5 adrenal gland: 1.4 -GAS2L3 ENSG00000139354 Growth arrest-specific 2 like 3 12 100573683-100628286 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048593 Approved Mixed gallbladder: 7.0 -TMEM132B KIAA1786, KIAA1906 ENSG00000139364 Transmembrane protein 132B 12 125186836-125662377 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035661, HPA035662 Uncertain Tissue enriched 7 cerebral cortex: 21.9 thyroid gland: 3.1 -SLC15A4 PHT1, PTR4 ENSG00000139370 Solute carrier family 15 (oligopeptide transporter), member 4 12 128793191-128823983 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA016713 Approved Expressed in all lymph node: 27.7 -TDG ENSG00000139372 Thymine DNA glycosylase 12 103965804-103988874 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052263 Supported Supported Nucleoplasm Expressed in all placenta: 23.6 -RITA1 C12orf52, FLJ14827, RITA ENSG00000139405 RBPJ interacting and tubulin associated 1 12 113185526-113192368 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039094, HPA039095, HPA061531 Supported Supported Nucleus Expressed in all fallopian tube: 20.2 -SDSL cSDH, SDS-RS1 ENSG00000139410 Serine dehydratase-like 12 113422237-113438276 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005740 Approved Approved Cytosol Mixed thyroid gland: 35.2 -MMAB cblB, CFAP23 ENSG00000139428 Methylmalonic aciduria (cobalamin deficiency) cblB type 12 109553737-109573874 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039017 Approved Approved Mitochondria Expressed in all adrenal gland: 32.7 -GLTP ENSG00000139433 Glycolipid transfer protein 12 109850943-109880488 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056461 Approved Supported Cytosol Expressed in all skin: 294.6 -GIT2 KIAA0148 ENSG00000139436 G protein-coupled receptor kinase interacting ArfGAP 2 12 109929792-109996389 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004681 Approved Approved Microtubules Expressed in all spleen: 48.6 -TCHP MGC10854, TpMs ENSG00000139437 Trichoplein, keratin filament binding 12 109900264-109983841 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038638, HPA061543 Supported Supported Plasma membrane
Centrosome
Cytosol Expressed in all skin: 32.7 -FAM222A C12orf34, FLJ14721 ENSG00000139438 Family with sequence similarity 222, member A 12 109714228-109770507 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA040181 Uncertain Approved Nucleoplasm
Plasma membrane
Focal adhesion sites
Mitochondria Tissue enhanced 0 cerebral cortex: 20.1;testis: 16.6 adrenal gland: 9.9 -FOXN4 ENSG00000139445 Forkhead box N4 12 109277979-109309220 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA050018 Uncertain Approved Nucleus
Mitochondria
Cytosol Tissue enriched 13 testis: 10.7 cervix: 0.7 -NUP58 KIAA0410, NUP45, NUPL1 ENSG00000139496 Nucleoporin 58kDa 13 25301524-25349800 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039360 Approved Approved Plasma membrane
Mitochondria
Cytosol Expressed in all testis: 86.6 -MTMR6 ENSG00000139505 Myotubularin related protein 6 13 25246201-25288009 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 30.5 -SLC46A3 DKFZp686A1775, FLJ42613 ENSG00000139508 Solute carrier family 46, member 3 13 28700064-28718970 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039930 Uncertain Approved Plasma membrane
Actin filaments
Cytosol Expressed in all small intestine: 89.4 -SLC7A1 ATRC1, CAT-1, ERR, HCAT1, REC1L ENSG00000139514 Solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 13 29509410-29595688 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039721 Approved Mixed esophagus: 42.0 -PDX1 IDX-1, IPF1, MODY4, PDX-1, STF-1 ENSG00000139515 Pancreatic and duodenal homeobox 1 13 27920020-27926231 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB025873, HPA059146 Supported Supported Nucleoplasm Tissue enriched 7 duodenum: 44.8 stomach: 6.3 -LNX2 MGC46315, PDZRN1 ENSG00000139517 Ligand of numb-protein X 2 13 27545911-27620404 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040698 Approved Approved Vesicles
Plasma membrane Expressed in all testis: 23.2 -SUOX ENSG00000139531 Sulfite oxidase 12 55997180-56006641 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038208, HPA038209 Approved Expressed in all parathyroid gland: 106.1 -CCDC65 CFAP250, CILD27, DRC2, FAP250, FLJ35732, NYD-SP28 ENSG00000139537 Coiled-coil domain containing 65 12 48904110-48931840 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038520, HPA057573 Uncertain Approved Vesicles
Microtubule organizing center Group enriched 11 fallopian tube: 42.4;testis: 67.5 lung: 4.8 -SLC39A5 ENSG00000139540 Solute carrier family 39 (zinc transporter), member 5 12 56230049-56237846 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018423 Approved Nucleoplasm
Vesicles
Cytosol Group enriched 12 colon: 74.5;duodenum: 247.0;kidney: 114.6;liver: 85.7;pancreas: 53.1;rectum: 49.7;small intestine: 245.4 gallbladder: 10.0 -TARBP2 ENSG00000139546 TAR (HIV-1) RNA binding protein 2 12 53500921-53506431 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051181, HPA061454, CAB069406 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all placenta: 18.6 -RDH16 RODH-4, SDR9C8 ENSG00000139547 Retinol dehydrogenase 16 (all-trans) 12 56951431-56959374 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038518 Supported Tissue enriched 71 liver: 278.4 prostate: 3.9 -DHH HHG-3, MGC35145 ENSG00000139549 Desert hedgehog 12 49089421-49094819 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034386 Uncertain Tissue enriched 21 testis: 20.8 placenta: 0.9 -ACVRL1 ACVRLK1, ALK1, HHT, HHT2, ORW2 ENSG00000139567 Activin A receptor type II-like 1 12 51906908-51923361 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007041 Approved Tissue enhanced 0 placenta: 125.5 lung: 76.6 -GPR84 EX33 ENSG00000139572 G protein-coupled receptor 84 12 54362445-54364487 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA027603 Supported Tissue enhanced 0 appendix: 11.9;bone marrow: 14.7 adipose tissue: 5.9 -NPFF FMRFAL ENSG00000139574 Neuropeptide FF-amide peptide precursor 12 53506690-53507638 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 1173 epididymis: 982.2 duodenum: 0.8 -NABP2 hSSB1, MGC2731, OBFC2B, SOSS-B1, SSB1 ENSG00000139579 Nucleic acid binding protein 2 12 56222015-56229854 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044615, HPA057213 Supported Validated Nucleoplasm Expressed in all cerebral cortex: 42.1 -N4BP2L1 CG018 ENSG00000139597 NEDD4 binding protein 2-like 1 13 32400723-32428311 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038971 Approved Uncertain Nucleoplasm
Cytosol Expressed in all ovary: 47.6 -CELA1 ELA1 ENSG00000139610 Chymotrypsin-like elastase family, member 1 12 51328443-51346679 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adrenal gland: 2.5;pancreas: 1.3 lymph node: 0.9 -SMARCC2 BAF170, CRACC2, Rsc8 ENSG00000139613 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 12 56162983-56189567 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004321, HPA021213, HPA061788 Supported Validated Nucleoplasm Expressed in all cerebral cortex: 77.0 -BRCA2 BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11 ENSG00000139618 Breast cancer 2, early onset 13 32315474-32400266 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026815 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 5.1 bone marrow: 4.1 -KANSL2 C12orf41, FLJ20436, NSL2 ENSG00000139620 KAT8 regulatory NSL complex subunit 2 12 48653401-48682238 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038497, HPA038498 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all bone marrow: 31.9 -CERS5 FLJ25304, LASS5, MGC45411, Trh4 ENSG00000139624 Ceramide synthase 5 12 50129306-50167533 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026589 Approved Approved Nucleus
Nucleoli Expressed in all parathyroid gland: 37.9 -MAP3K12 DLK, MEKK12, MUK, ZPK, ZPKP1 ENSG00000139625 Mitogen-activated protein kinase kinase kinase 12 12 53479669-53500063 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039936, HPA071996 Approved Approved Nucleus
Cell Junctions Mixed gallbladder: 24.0 -ITGB7 ENSG00000139626 Integrin, beta 7 12 53191318-53207307 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042277 Approved Plasma membrane
Cytosol Mixed spleen: 32.8 -GALNT6 GalNAc-T6 ENSG00000139629 Polypeptide N-acetylgalactosaminyltransferase 6 12 51351247-51392867 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011762, HPA017086 Supported Approved Nucleoplasm
Golgi apparatus Tissue enhanced 0 stomach: 61.9 cervix: 49.2 -CSAD CSD, PCAP ENSG00000139631 Cysteine sulfinic acid decarboxylase 12 53157663-53180909 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039487 Approved Expressed in all skin: 70.8 -LMBR1L FLJ10494, KIAA1174 ENSG00000139636 Limb development membrane protein 1-like 12 49096551-49110900 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 27.5 endometrium: 9.0 -C12orf10 Gamm1, MYG, MYG1 ENSG00000139637 Chromosome 12 open reading frame 10 12 53299686-53307177 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038626, HPA038627 Approved Supported Supported Nucleoplasm Expressed in all testis: 114.2 -ESYT1 FAM62A, KIAA0747, MBC2 ENSG00000139641 Extended synaptotagmin-like protein 1 12 56118250-56144671 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016858, HPA076926 Approved Supported Endoplasmic reticulum
Vesicles Expressed in all adipose tissue: 114.2 -TMBIM6 BAXI1, BI-1, TEGT ENSG00000139644 Transmembrane BAX inhibitor motif containing 6 12 49707725-49764934 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017378 Approved Expressed in all kidney: 1179.3 -ANKRD52 FLJ34236, PP6-ARS-C ENSG00000139645 Ankyrin repeat domain 52 12 56237807-56258391 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043815 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all parathyroid gland: 30.5 -KRT71 K6IRS1, KRT6IRS, KRT6IRS1 ENSG00000139648 Keratin 71, type II 12 52543909-52553147 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049404 Supported Group enriched 34 breast: 1.4;epididymis: 5.3 spleen: 0.1 -ZNF740 Zfp740 ENSG00000139651 Zinc finger protein 740 12 53180700-53195141 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035691 Approved Approved Nucleus Expressed in all parathyroid gland: 14.2 -SMIM2 C13orf44, MGC5590 ENSG00000139656 Small integral membrane protein 2 13 44143543-44161257 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA026891 Approved Tissue enriched 8 testis: 40.8 epididymis: 5.2 -WDFY2 ZFYVE22 ENSG00000139668 WD repeat and FYVE domain containing 2 13 51584455-51767707 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed skin: 21.4 -HNRNPA1L2 LOC144983 ENSG00000139675 Heterogeneous nuclear ribonucleoprotein A1-like 2 13 52640786-52643796 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed ovary: 5.9 -LPAR6 P2RY5, P2Y5 ENSG00000139679 Lysophosphatidic acid receptor 6 13 48389567-48444704 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028934, HPA076273 Approved Supported Vesicles
Plasma membrane Expressed in all placenta: 100.1 -ESD ENSG00000139684 Esterase D 13 46771256-46797232 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039700 Approved Approved Golgi apparatus
Cytosol Expressed in all thyroid gland: 244.5 -RB1 OSRC, PPP1R130, RB ENSG00000139687 Retinoblastoma 1 13 48303751-48481986 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000095, CAB016687, HPA050082 Supported Validated Nucleoplasm Expressed in all thyroid gland: 36.0 -SBNO1 FLJ10701, FLJ10833, MOP3, Sno ENSG00000139697 Strawberry notch homolog 1 (Drosophila) 12 123289109-123364843 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042388 Approved Approved Nucleoplasm Expressed in all testis: 125.8 -MORN3 ENSG00000139714 MORN repeat containing 3 12 121648742-121672631 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038709, HPA038710 Uncertain Approved Nucleoplasm Tissue enhanced 0 fallopian tube: 6.7 testis: 5.1 -SETD1B KIAA1076, KMT2G, Set1B ENSG00000139718 SET domain containing 1B 12 121804180-121832584 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021667, HPA059412 Approved Validated Nucleoplasm Expressed in all endometrium: 19.0 -VPS33A ENSG00000139719 Vacuolar protein sorting 33 homolog A (S. cerevisiae) 12 122229564-122266521 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038701 Approved Nucleoplasm Mixed parathyroid gland: 13.7 -VPS37B FLJ12750 ENSG00000139722 Vacuolar protein sorting 37 homolog B (S. cerevisiae) 12 122865328-122896444 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038217, HPA038218 Supported Expressed in all esophagus: 34.9 -RHOF ARHF, FLJ20247, RIF ENSG00000139725 Ras homolog family member F (in filopodia) 12 121777754-121803403 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045912 Uncertain Nucleus
Golgi apparatus Expressed in all lymph node: 46.8 -DENR DRP, DRP1, SMAP-3 ENSG00000139726 Density-regulated protein 12 122752774-122771064 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021783 Approved Approved Cytosol Expressed in all parathyroid gland: 106.8 -DIAPH3 AN, AUNA1, DRF3, FLJ34705, NSDAN ENSG00000139734 Diaphanous-related formin 3 13 59665583-60163987 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032151 Supported Plasma membrane
Microtubules Tissue enriched 7 testis: 33.9 placenta: 5.0 -SLAIN1 C13orf32, FLJ30046 ENSG00000139737 SLAIN motif family, member 1 13 77697854-77764242 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040798 Approved Nucleoplasm
Intermediate filaments
Cytosol Expressed in all cerebral cortex: 217.7 -RBM26 ARRS2, C13orf10, FLJ20957, PPP1R132, PRO1777, SE70-2, ZC3H17 ENSG00000139746 RNA binding motif protein 26 13 79311824-79406477 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040252 Approved Approved Nuclear speckles Expressed in all testis: 55.8 -SRRM4 KIAA1853, nSR100 ENSG00000139767 Serine/arginine repetitive matrix 4 12 118981495-119163051 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052783 Uncertain Tissue enriched 9 cerebral cortex: 13.5 adrenal gland: 1.5 -METTL21C C13orf39, LOC196541 ENSG00000139780 Methyltransferase like 21C 13 102685744-102694504 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 13 epididymis: 41.8 seminal vesicle: 3.1 -MBNL2 MBLL, MBLL39 ENSG00000139793 Muscleblind-like splicing regulator 2 13 97221434-97394120 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062685 Supported Nucleoplasm Expressed in all adrenal gland: 84.5 -RNF113B RNF161, ZNF183L1 ENSG00000139797 Ring finger protein 113B 13 98175785-98177265 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 587 testis: 58.7 epididymis: 0.0 -ZIC5 ENSG00000139800 Zic family member 5 13 99962964-99971909 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA074045 Uncertain Nucleoplasm
Vesicles Group enriched 45 cerebral cortex: 2.3;testis: 6.6 adipose tissue: 0.0 -ABHD13 bA153I24.2, BEM46L1, C13orf6, FLJ14906 ENSG00000139826 Abhydrolase domain containing 13 13 108218379-108234255 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA032143, HPA032144 Approved Approved Cytosol Mixed thyroid gland: 12.6 -RAB20 FLJ20429 ENSG00000139832 RAB20, member RAS oncogene family 13 110523066-110561733 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052111, HPA068647 Uncertain Supported Golgi apparatus
Vesicles Mixed spleen: 42.7 -GRTP1 FLJ22474, TBC1D6 ENSG00000139835 Growth hormone regulated TBC protein 1 13 113324164-113364148 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046201 Approved Mixed duodenum: 48.5 -CUL4A ENSG00000139842 Cullin 4A 13 113208193-113267108 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058979 Approved Nucleoplasm Expressed in all testis: 89.9 -TTC6 C14orf25, NCRNA00291 ENSG00000139865 Tetratricopeptide repeat domain 6 14 37595847-38041442 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA069293 Uncertain Approved Centrosome Group enriched 6 breast: 10.4;prostate: 26.3;testis: 10.4 stomach: 2.6 -SSTR1 ENSG00000139874 Somatostatin receptor 1 14 38207999-38213067 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA031506 Approved Tissue enhanced 0 cerebral cortex: 13.6;duodenum: 14.6;stomach: 21.4 small intestine: 9.3 -CDH24 CDH11L ENSG00000139880 Cadherin 24, type 2 14 23047062-23057538 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054135 Approved Nucleoplasm Mixed endometrium: 8.4 -REM2 FLJ38964 ENSG00000139890 RAS (RAD and GEM)-like GTP binding 2 14 22883165-22887686 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 6.0;parathyroid gland: 5.3 testis: 2.9 -CBLN3 ENSG00000139899 Cerebellin 3 precursor 14 24426532-24430954 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041266 Supported Approved Nucleus Mixed spleen: 17.7 -TSSK4 C14orf20, STK22E ENSG00000139908 Testis-specific serine kinase 4 14 24205697-24208362 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA060660 Approved Cell Junctions Tissue enhanced 0 testis: 42.8 parathyroid gland: 10.8 -NOVA1 ENSG00000139910 Neuro-oncological ventral antigen 1 14 26443093-26597754 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004155 Uncertain Supported Nucleus
Nucleoli Tissue enhanced 0 cerebral cortex: 62.3 breast: 31.3 -FITM1 FIT1 ENSG00000139914 Fat storage-inducing transmembrane protein 1 14 24131275-24132849 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA019842 Uncertain Group enriched 14 heart muscle: 45.3;skeletal muscle: 113.0 spleen: 5.5 -MDGA2 MAMDC1 ENSG00000139915 MAM domain containing glycosylphosphatidylinositol anchor 2 14 46839629-47674954 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003084 Uncertain Group enriched 15 cerebral cortex: 6.3;testis: 6.9 skin: 0.4 -TMX1 PDIA11, TMX, TXNDC, TXNDC1 ENSG00000139921 Thioredoxin-related transmembrane protein 1 14 51240162-51257546 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003085 Approved Supported Nucleoli
Endoplasmic reticulum Expressed in all thyroid gland: 19.8 -FRMD6 C14orf31, EX1, MGC17921, willin ENSG00000139926 FERM domain containing 6 14 51489100-51730727 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001297 Uncertain Approved Approved Mitochondria Mixed endometrium: 125.3 -PELI2 ENSG00000139946 Pellino E3 ubiquitin protein ligase family member 2 14 56117814-56301526 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053182 Uncertain Approved Nucleus
Nucleoli
Intermediate filaments Mixed testis: 19.0 -RTN1 NSP ENSG00000139970 Reticulon 1 14 59595976-59870966 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002745, HPA040945, HPA044249 Supported Validated Endoplasmic reticulum Tissue enriched 8 cerebral cortex: 412.9 parathyroid gland: 48.8 -C14orf37 ENSG00000139971 Chromosome 14 open reading frame 37 14 57999735-58298139 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001580, HPA001789 Approved Approved Plasma membrane Mixed kidney: 8.8 -SYT16 CHR14SYT, Strep14, SYT14L, yt14r ENSG00000139973 Synaptotagmin XVI 14 61995823-62112550 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA004199 Uncertain Tissue enriched 6 cerebral cortex: 13.9 prostate: 2.2 -SLC38A6 NAT-1 ENSG00000139974 Solute carrier family 38, member 6 14 60981114-61083733 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018508 Approved Approved Plasma membrane
Cell Junctions
Microtubules Mixed parathyroid gland: 24.3 -NAA30 C14orf35, FLJ35355, MAK3, Mak3p, NAT12 ENSG00000139977 N(alpha)-acetyltransferase 30, NatC catalytic subunit 14 57390544-57415917 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057824 Uncertain Supported Cytosol Expressed in all testis: 34.2 -ADAM21 ADAM31 ENSG00000139985 ADAM metallopeptidase domain 21 14 70452157-70459899 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059016 Uncertain Tissue enriched 31 testis: 15.4 cerebral cortex: 0.5 -RDH12 FLJ30273, LCA13, RP53, SDR7C2 ENSG00000139988 Retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 14 67701886-67734452 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 gallbladder: 27.9;skin: 58.4 kidney: 13.6 -DCAF5 BCRG2, BCRP2, D14S1461E, KIAA1824, WDR22 ENSG00000139990 DDB1 and CUL4 associated factor 5 14 69050881-69153150 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041575, HPA048098 Uncertain Approved Mitochondria Expressed in all testis: 111.2 -RAB15 ENSG00000139998 RAB15, member RAS oncogene family 14 64945814-64972776 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041177 Uncertain Approved Vesicles
Microtubule organizing center Expressed in all cerebral cortex: 63.0 -WDR89 C14orf150, MGC9907 ENSG00000140006 WD repeat domain 89 14 63597039-63641861 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000813 Uncertain Approved Intermediate filaments
Cytosol Expressed in all thyroid gland: 20.6 -ESR2 Erb, NR3A2 ENSG00000140009 Estrogen receptor 2 (ER beta) 14 64084232-64338112 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level CAB022544 Approved Nucleoplasm Tissue enhanced 0 testis: 10.5 adrenal gland: 6.3 -KCNH5 eag2, H-EAG2, Kv10.2 ENSG00000140015 Potassium channel, voltage gated eag related subfamily H, member 5 14 62699454-63102037 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA030487 Uncertain Uncertain Microtubules
Mitotic spindle Tissue enhanced 0 adrenal gland: 1.4;cerebral cortex: 3.6 testis: 0.7 -STON2 STN2, STNB2 ENSG00000140022 Stonin 2 14 81260656-81436465 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003086 Approved Supported Nucleoli
Cytosol Mixed cerebral cortex: 34.3 -EFCAB11 C14orf143 ENSG00000140025 EF-hand calcium binding domain 11 14 89794669-89954777 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051209 Approved Cell Junctions
Cytosol Tissue enhanced 0 testis: 59.8 fallopian tube: 17.1 -GPR65 hTDAG8, TDAG8 ENSG00000140030 G protein-coupled receptor 65 14 88005124-88014811 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA054454 Approved Cytosol Mixed spleen: 13.5 -PTGR2 FLJ39091, ZADH1 ENSG00000140043 Prostaglandin reductase 2 14 73851844-73886827 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001125 Approved Approved Vesicles Mixed thyroid gland: 21.3 -JDP2 JUNDM2 ENSG00000140044 Jun dimerization protein 2 14 75427716-75474111 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059511 Supported Approved Nucleoplasm
Nuclear speckles Expressed in all spleen: 87.3 -AK7 FLJ32864 ENSG00000140057 Adenylate kinase 7 14 96392111-96489427 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003543 Approved Tissue enhanced 0 fallopian tube: 38.5 parathyroid gland: 15.2 -FAM181A C14orf152 ENSG00000140067 Family with sequence similarity 181, member A 14 93918894-93929608 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA001603 Supported Group enriched 5 cerebral cortex: 3.4;fallopian tube: 3.2;testis: 13.9 thyroid gland: 1.3 -SLC24A4 NCKX4 ENSG00000140090 Solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 14 92322581-92501483 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 7.1 spleen: 2.7 -FBLN5 ARMD3, DANCE, EVEC, UP50 ENSG00000140092 Fibulin 5 14 91869412-91947987 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000848, HPA000868, CAB025843 Supported Approved Plasma membrane
Cytosol Expressed in all gallbladder: 221.9 -SERPINA10 PZI, ZPI ENSG00000140093 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 14 94280455-94293271 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048739 Approved Nucleoplasm
Cytosol Tissue enriched 89 liver: 193.5 bone marrow: 2.1 -C14orf79 ENSG00000140104 Chromosome 14 open reading frame 79 14 104985775-105010482 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042052, HPA061117 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Mixed fallopian tube: 23.9 -WARS IFI53, IFP53 ENSG00000140105 Tryptophanyl-tRNA synthetase 14 100333788-100376805 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005573, HPA018944 Validated Cytosol Expressed in all placenta: 468.8 -SLC25A47 C14orf68 ENSG00000140107 Solute carrier family 25, member 47 14 100323337-100330378 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 166 liver: 101.0 duodenum: 0.6 -WDR20 DMR, FLJ33659, MGC33177 ENSG00000140153 WD repeat domain 20 14 102139503-102224847 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 41.2 -NIPA2 ENSG00000140157 Non imprinted in Prader-Willi/Angelman syndrome 2 15 22838641-22868384 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA067160, HPA071342 Approved Approved Golgi apparatus Expressed in all appendix: 45.7 -SLC12A6 ACCPN, KCC3 ENSG00000140199 Solute carrier family 12 (potassium/chloride transporter), member 6 15 34229996-34338060 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034563 Uncertain Approved Vesicles
Cytosol Mixed testis: 46.2 -DUOXA1 FLJ32334, mol, NIP, NUMBIP ENSG00000140254 Dual oxidase maturation factor 1 15 45117367-45129938 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041578 Approved Tissue enhanced 0 esophagus: 122.6;skin: 107.8;thyroid gland: 111.5 epididymis: 59.7 -MFAP1 ENSG00000140259 Microfibrillar-associated protein 1 15 43804492-43824802 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042370 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 49.6 -TCF12 bHLHb20, HEB, HsT17266, HTF4 ENSG00000140262 Transcription factor 12 15 56918623-57299281 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004432, HPA065827 Approved Supported Nucleoplasm
Nuclear speckles Expressed in all cervix: 115.4 -SORD ENSG00000140263 Sorbitol dehydrogenase 15 45023104-45077185 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040260, HPA040621 Supported Approved Cytosol Expressed in all cervix: 401.6 -SERF2 4F5REL, FAM2C, H4F5rel, HsT17089 ENSG00000140264 Small EDRK-rich factor 2 15 43777087-43802589 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056613 Uncertain Nucleus
Nucleoli Expressed in all epididymis: 896.5 -ZSCAN29 FLJ35867, Zfp690, ZNF690 ENSG00000140265 Zinc finger and SCAN domain containing 29 15 43358172-43371025 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007241, HPA011109 Approved Approved Nucleoplasm
Plasma membrane
Actin filaments Expressed in all testis: 27.5 -DUOXA2 ENSG00000140274 Dual oxidase maturation factor 2 15 45114321-45118421 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA063548 Supported Tissue enhanced 0 gallbladder: 97.7;urinary bladder: 25.6 thyroid gland: 13.6 -DUOX2 LNOX2, P138(TOX), P138-TOX, THOX2 ENSG00000140279 Dual oxidase 2 15 45092650-45114344 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 gallbladder: 448.6;thyroid gland: 124.3;urinary bladder: 90.1 stomach: 38.5 -LYSMD2 MGC35274 ENSG00000140280 LysM, putative peptidoglycan-binding, domain containing 2 15 51723011-51751585 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040460 Approved Approved Nuclear bodies
Mitochondria Expressed in all cerebral cortex: 38.3 -SLC27A2 ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS ENSG00000140284 Solute carrier family 27 (fatty acid transporter), member 2 15 50182196-50236395 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026089 Supported Group enriched 5 epididymis: 79.2;kidney: 160.9;liver: 145.2 placenta: 24.5 -FGF7 KGF ENSG00000140285 Fibroblast growth factor 7 15 49423096-49488775 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043605 Uncertain Approved Nucleus
Nucleoli Tissue enhanced 0 gallbladder: 55.6 endometrium: 31.6 -HDC ENSG00000140287 Histidine decarboxylase 15 50241947-50266026 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038891 Approved Tissue enhanced 0 epididymis: 52.1 gallbladder: 17.4 -GCNT3 C2/4GnT, C2GnT-M, C2GnT2 ENSG00000140297 Glucosaminyl (N-acetyl) transferase 3, mucin type 15 59594875-59640239 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA011154 Approved Approved Golgi apparatus
Vesicles Tissue enhanced 0 colon: 144.6;gallbladder: 118.5;rectum: 136.6;small intestine: 141.0 duodenum: 100.5 -BNIP2 BNIP-2, Nip2 ENSG00000140299 BCL2/adenovirus E1B 19kDa interacting protein 2 15 59659146-59689534 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026843 Approved Expressed in all bone marrow: 84.4 -GTF2A2 HsT18745, TFIIA ENSG00000140307 General transcription factor IIA, 2, 12kDa 15 59638062-59657541 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056239 Supported Nucleoplasm Expressed in all testis: 367.4 -SRP14 ALURBP, MGC14326 ENSG00000140319 Signal recognition particle 14kDa (homologous Alu RNA binding protein) 15 40035739-40039188 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053738, HPA065118 Approved Nucleus
Nucleoli Expressed in all thyroid gland: 372.6 -BAHD1 KIAA0945 ENSG00000140320 Bromo adjacent homology domain containing 1 15 40439721-40468242 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041196 Supported Nucleoplasm Expressed in all testis: 27.4 -DISP2 DISPB, HsT16908, KIAA1742 ENSG00000140323 Dispatched homolog 2 (Drosophila) 15 40358235-40378639 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059903 Uncertain Approved Nucleoplasm
Vesicles Tissue enhanced 0 cerebral cortex: 7.5 thyroid gland: 1.9 -CDAN1 CDA-I, CDAI ENSG00000140326 Codanin 1 15 42723559-42737126 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039404, HPA040787 Supported Validated Plasma membrane
Cytosol Expressed in all ovary: 15.1 -TLE3 ESG, ESG3, GRG3, HsT18976, KIAA1547 ENSG00000140332 Transducin-like enhancer of split 3 15 70047790-70098176 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054116 Approved Supported Nucleoplasm Mixed bone marrow: 48.8 -ANP32A C15orf1, I1PP2A, LANP, MAPM, mapmodulin, PHAPI, PP32 ENSG00000140350 Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 15 68778535-68820897 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005231, HPA063133, HPA067561 Supported Approved Nucleoplasm
Centrosome
Cytosol Expressed in all lymph node: 183.8 -COMMD4 FLJ20452 ENSG00000140365 COMM domain containing 4 15 75335891-75343224 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066957 Uncertain Supported Nucleus
Plasma membrane Expressed in all testis: 76.3 -UBE2Q2 DKFZp762C143 ENSG00000140367 Ubiquitin-conjugating enzyme E2Q family member 2 15 75843285-75901078 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 51.3 -PSTPIP1 CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP ENSG00000140368 Proline-serine-threonine phosphatase interacting protein 1 15 76993359-77037332 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010600 Supported Tissue enhanced 0 bone marrow: 37.7 appendix: 16.8 -ETFA EMA, GA2, MADD ENSG00000140374 Electron-transfer-flavoprotein, alpha polypeptide 15 76215355-76311472 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018990, HPA018993, HPA018996, HPA024089 Supported Validated Mitochondria Expressed in all liver: 196.7 -BCL2A1 ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1 ENSG00000140379 BCL2-related protein A1 15 79960889-79971446 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 117.8;bone marrow: 277.7 lymph node: 62.9 -HMG20A FLJ10739, HMGX1, HMGXB1 ENSG00000140382 High mobility group 20A 15 77420412-77485607 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008126 Supported Approved Nucleus Expressed in all spleen: 49.8 -SCAPER Zfp291, ZNF291 ENSG00000140386 S-phase cyclin A-associated protein in the ER 15 76347904-76905444 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046253, HPA061180 Approved Supported Nucleus
Cytosol Expressed in all testis: 38.2 -TSPAN3 TM4-A, TM4SF8, TSPAN-3 ENSG00000140391 Tetraspanin 3 15 77041404-77083984 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015996 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all epididymis: 519.8 -WDR61 REC14 ENSG00000140395 WD repeat domain 61 15 78277835-78299794 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039932, HPA040065 Supported Validated Nucleoplasm
Cytosol Expressed in all epididymis: 128.8 -NCOA2 bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2 ENSG00000140396 Nuclear receptor coactivator 2 8 70109762-70403805 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060243 Supported Nucleoplasm
Nuclear bodies Expressed in all epididymis: 35.4 -NEIL1 FLJ22402, FPG1, hFPG1, NEI1 ENSG00000140398 Nei-like DNA glycosylase 1 15 75346955-75357114 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054084 Approved Supported Nucleoplasm Expressed in all adrenal gland: 10.6 -MAN2C1 MANA, MANA1 ENSG00000140400 Mannosidase, alpha, class 2C, member 1 15 75355207-75368630 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040627, HPA067407 Uncertain Validated Nucleoplasm Expressed in all parathyroid gland: 46.6 -DNAJA4 PRO1472 ENSG00000140403 DnaJ (Hsp40) homolog, subfamily A, member 4 15 78264086-78282196 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004646, HPA041790 Uncertain Approved Plasma membrane
Cytosol Expressed in all testis: 95.2 -MESDC1 MGC99595 ENSG00000140406 Mesoderm development candidate 1 15 81000944-81005788 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062713 Approved Vesicles Mixed spleen: 14.6 -TPM1 C15orf13, CMH3 ENSG00000140416 Tropomyosin 1 (alpha) 15 63042632-63071915 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000261, HPA009066, CAB017698, HPA047089, HPA053624 Supported Approved Actin filaments
Cytosol Expressed in all heart muscle: 6465.2 -IGF1R CD221, IGFIR, IGFR, JTK13, MGC18216 ENSG00000140443 Insulin-like growth factor 1 receptor 15 98648971-98964530 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010268, HPA045563 Uncertain Uncertain Vesicles Mixed prostate: 24.7 -ARRDC4 FLJ36045 ENSG00000140450 Arrestin domain containing 4 15 97960698-97973838 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042109 Approved Expressed in all skin: 42.1 -PIF1 C15orf20, FLJ22692 ENSG00000140451 PIF1 5'-to-3' DNA helicase 15 64815632-64825668 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018701 Supported Supported Nucleoplasm Mixed lymph node: 5.4 -USP3 ENSG00000140455 Ubiquitin specific peptidase 3 15 63504511-63594640 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053275, HPA060513 Supported Nucleus Expressed in all bone marrow: 32.1 -CYP11A1 CYP11A, P450SCC ENSG00000140459 Cytochrome P450, family 11, subfamily A, polypeptide 1 15 74337759-74367740 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016436 Supported Tissue enriched 11 adrenal gland: 752.7 testis: 68.6 -BBS4 ENSG00000140463 Bardet-Biedl syndrome 4 15 72686179-72738476 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039418 Approved Supported Cytosol Expressed in all testis: 37.3 -PML MYL, RNF71, TRIM19 ENSG00000140464 Promyelocytic leukemia 15 73994673-74047812 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008312, CAB010194, CAB016304 Supported Validated Nuclear bodies Expressed in all adipose tissue: 45.0 -CYP1A1 CP11, CYP1, P1-450, P450-C, P450DX ENSG00000140465 Cytochrome P450, family 1, subfamily A, polypeptide 1 15 74719542-74725610 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB018654 Uncertain Group enriched 8 liver: 33.8;small intestine: 21.0;urinary bladder: 84.1 breast: 5.7 -ADAMTS17 FLJ16363, FLJ32769 ENSG00000140470 ADAM metallopeptidase with thrombospondin type 1 motif, 17 15 99971589-100342005 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062487 Approved Nucleus Mixed endometrium: 3.5 -LINS1 LINS, WINS1 ENSG00000140471 Lines homolog 1 15 100559369-100603230 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038578, HPA038579 Approved Approved Nucleoplasm Expressed in all thyroid gland: 14.0 -ULK3 DKFZP434C131, FLJ90566 ENSG00000140474 Unc-51 like kinase 3 15 74836116-74843346 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040474 Approved Expressed in all esophagus: 28.6 -GOLGA6D ENSG00000140478 Golgin A6 family, member D 15 75258558-75295530 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA044978, HPA050087 Supported Tissue enriched 27 testis: 14.3 liver: 0.5 -PCSK6 PACE4, SPC4 ENSG00000140479 Proprotein convertase subtilisin/kexin type 6 15 101297142-101525202 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004774 Uncertain Tissue enhanced 0 liver: 90.2;spleen: 126.5 placenta: 53.5 -CCDC33 CT61, FLJ32855 ENSG00000140481 Coiled-coil domain containing 33 15 74236289-74336472 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 19 fallopian tube: 54.8;testis: 22.2 lung: 2.0 -CELF6 BRUNOL6 ENSG00000140488 CUGBP, Elav-like family member 6 15 72284727-72320129 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046985, HPA053526 Uncertain Approved Cytosol Mixed cerebral cortex: 11.1 -SCAMP2 ENSG00000140497 Secretory carrier membrane protein 2 15 74843730-74873365 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014699, HPA019194 Approved Supported Golgi apparatus
Vesicles Expressed in all parathyroid gland: 126.3 -CYP1A2 CP12, P3-450 ENSG00000140505 Cytochrome P450, family 1, subfamily A, polypeptide 2 15 74748844-74756202 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016531 Supported Tissue enriched 168 liver: 268.7 thyroid gland: 1.5 -LMAN1L ERGIC-53L, ERGL ENSG00000140506 Lectin, mannose-binding, 1 like 15 74812716-74825758 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 prostate: 81.3;spleen: 32.1 heart muscle: 15.7 -HAPLN3 EXLD1, HsT19883 ENSG00000140511 Hyaluronan and proteoglycan link protein 3 15 88877288-88895626 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039237 Uncertain Approved Plasma membrane
Cytosol Tissue enhanced 0 appendix: 14.3;lymph node: 11.0 spleen: 4.0 -RHCG C15orf6, PDRC2, RHGK, SLC42A3 ENSG00000140519 Rh family, C glycoprotein 15 89471398-89496613 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041874, HPA043317 Supported Tissue enriched 7 esophagus: 2912.7 tonsil: 436.1 -POLG POLG1, POLGA ENSG00000140521 Polymerase (DNA directed), gamma 15 89316305-89334861 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056821 Approved Expressed in all spleen: 21.6 -RLBP1 CRALBP ENSG00000140522 Retinaldehyde binding protein 1 15 89209869-89221751 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042051, HPA044083 Approved Approved Nucleoplasm
Centrosome
Cytosol Tissue enriched 9 cerebral cortex: 6.2 testis: 0.6 -FANCI FLJ10719, KIAA1794 ENSG00000140525 Fanconi anemia, complementation group I 15 89243949-89317261 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039972, HPA040379 Approved Validated Nucleoplasm Tissue enhanced 0 testis: 60.4 lymph node: 29.0 -ABHD2 LABH2 ENSG00000140526 Abhydrolase domain containing 2 15 89087459-89202360 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA005999 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 99.6 -WDR93 ENSG00000140527 WD repeat domain 93 15 89690797-89743638 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046196, HPA048112 Uncertain Uncertain Actin filaments Tissue enhanced 0 fallopian tube: 14.1;testis: 21.1 epididymis: 5.7 -TICRR C15orf42, FLJ41618, MGC45866, SLD3, Treslin ENSG00000140534 TOPBP1-interacting checkpoint and replication regulator 15 89575482-89631056 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049454, HPA055024 Validated Nucleoplasm Mixed testis: 2.7 -NTRK3 TRKC ENSG00000140538 Neurotrophic tyrosine kinase, receptor, type 3 15 87859751-88256768 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009233, HPA027484, HPA048065 Supported Supported Nuclear membrane
Nucleoli Tissue enhanced 0 cerebral cortex: 39.7 testis: 15.2 -DET1 FLJ10103 ENSG00000140543 De-etiolated homolog 1 (Arabidopsis) 15 88511559-88546675 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048873 Uncertain Approved Nucleoplasm
Microtubules Mixed ovary: 13.1 -MFGE8 BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10 ENSG00000140545 Milk fat globule-EGF factor 8 protein 15 88898683-88913411 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002753, HPA002807 Uncertain Approved Cytosol Expressed in all heart muscle: 288.2 -ZNF710 DKFZp547K1113, FLJ00306, FLJ37393 ENSG00000140548 Zinc finger protein 710 15 90001392-90082206 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA030226, HPA030227, HPA030228 Supported Approved Nucleoplasm
Mitochondria Expressed in all appendix: 20.9 -UNC45A GC-UNC45, SMAP-1 ENSG00000140553 Unc-45 myosin chaperone A 15 90930180-90954093 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039228 Approved Supported Nuclear speckles
Cytosol Expressed in all parathyroid gland: 48.5 -ST8SIA2 HsT19690, SIAT8B, ST8SIA-II, STX ENSG00000140557 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 15 92393828-92468728 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA054518 Approved Approved Microtubule organizing center Tissue enhanced 0 cerebral cortex: 2.1;heart muscle: 1.9 cervix: 1.2 -MCTP2 FLJ11175, FLJ33303 ENSG00000140563 Multiple C2 domains, transmembrane 2 15 94231538-94483952 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051176, HPA070541 Uncertain Validated Nucleoplasm
Cytosol Mixed placenta: 28.3 -FURIN FUR, PACE, PCSK3, SPC1 ENSG00000140564 Furin (paired basic amino acid cleaving enzyme) 15 90868592-90883458 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009499 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all salivary gland: 93.2 -IQGAP1 HUMORFA01, KIAA0051, p195, SAR1 ENSG00000140575 IQ motif containing GTPase activating protein 1 15 90388218-90502243 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013302, HPA014055 Supported Supported Plasma membrane
Cell Junctions Expressed in all endometrium: 119.6 -CRTC3 FLJ21868 ENSG00000140577 CREB regulated transcription coactivator 3 15 90529925-90645345 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043735, HPA063691 Uncertain Validated Nucleoplasm
Cytosol Expressed in all ovary: 50.5 -EFTUD1 FAM42A, FLJ13119, HsT19294, RIA1 ENSG00000140598 Elongation factor Tu GTP binding domain containing 1 15 82130230-82262763 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039654, HPA047110, HPA052345 Uncertain Approved Cytosol Expressed in all parathyroid gland: 23.1 -SH3GL3 CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13 ENSG00000140600 SH3-domain GRB2-like 3 15 83447228-83618743 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039381, HPA077877 Supported Approved Cytosol Group enriched 12 cerebral cortex: 30.0;testis: 38.3 lung: 2.9 -SEC11A SEC11L1, sid2895, SPC18, SPCS4A ENSG00000140612 SEC11 homolog A, signal peptidase complex subunit 15 84669538-84716716 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047533 Approved Nuclear membrane
Golgi apparatus Expressed in all thyroid gland: 211.4 -SEPT12 FLJ25410 ENSG00000140623 Septin 12 16 4777669-4788521 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041128 Uncertain Microtubules Tissue enriched 667 testis: 107.9 bone marrow: 0.1 -GLYR1 BM045, HIBDL, N-PAC, NP60 ENSG00000140632 Glyoxylate reductase 1 homolog (Arabidopsis) 16 4803203-4847342 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017022, HPA048226, HPA050136 Supported Validated Nucleoplasm
Nuclear speckles Expressed in all parathyroid gland: 109.7 -PMM2 CDG1, CDG1a, CDGS, PMI, PMI1 ENSG00000140650 Phosphomannomutase 2 16 8788823-8849331 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040852, HPA063649 Approved Nucleus
Cytosol Expressed in all rectum: 28.8 -SLC5A2 SGLT2 ENSG00000140675 Solute carrier family 5 (sodium/glucose cotransporter), member 2 16 31483002-31490860 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041603 Supported Tissue enriched 9 kidney: 25.3 testis: 2.8 -ITGAX CD11C ENSG00000140678 Integrin, alpha X (complement component 3 receptor 4 subunit) 16 31355134-31382997 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004458, HPA004723, CAB072871 Supported Tissue enhanced 0 appendix: 59.8;spleen: 60.0 bone marrow: 30.4 -TGFB1I1 ARA55, Hic-5, TSC-5 ENSG00000140682 Transforming growth factor beta 1 induced transcript 1 16 31471585-31477960 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020844 Approved Supported Focal adhesion sites
Cytosol Tissue enhanced 0 endometrium: 139.7;smooth muscle: 151.9 seminal vesicle: 109.6 -C16orf58 FLJ13868 ENSG00000140688 Chromosome 16 open reading frame 58 16 31489471-31509309 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024406 Uncertain Approved Nucleoplasm
Nucleoli
Golgi apparatus
Vesicles
Cytosol Expressed in all parathyroid gland: 81.3 -ARMC5 FLJ13063 ENSG00000140691 Armadillo repeat containing 5 16 31458080-31467166 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041524, HPA063706 Approved Approved Nucleoplasm
Focal adhesion sites
Cytosol Mixed bone marrow: 13.2 -PARN DAN ENSG00000140694 Poly(A)-specific ribonuclease 16 14435701-14632728 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006314, CAB011673, HPA012010 Supported Approved Nucleoli
Nuclear speckles Expressed in all parathyroid gland: 27.6 -FTO ALKBH9, KIAA1752, MGC5149 ENSG00000140718 Fat mass and obesity associated 16 53703963-54121941 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017123, HPA041086 Supported Approved Vesicles
Cytosol Expressed in all parathyroid gland: 75.4 -UQCRC2 QCR2, UQCR2 ENSG00000140740 Ubiquinol-cytochrome c reductase core protein II 16 21952660-21983660 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007998, HPA019146 Supported Validated Mitochondria Expressed in all heart muscle: 296.6 -CDR2 CDR62, Yo ENSG00000140743 Cerebellar degeneration-related protein 2, 62kDa 16 22345936-22437165 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018151, HPA023870 Uncertain Approved Nucleoplasm Expressed in all testis: 112.0 -IGSF6 DORA ENSG00000140749 Immunoglobulin superfamily, member 6 16 21639537-21652660 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041023, HPA041072 Uncertain Tissue enhanced 0 spleen: 64.7 appendix: 37.2 -ARHGAP17 FLJ10308, FLJ13219, NADRIN, RICH1, WBP15 ENSG00000140750 Rho GTPase activating protein 17 16 24919385-25015666 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041703 Approved Approved Nucleus
Cytosol Expressed in all spleen: 71.6 -MYLK3 caMLCK, MLCK ENSG00000140795 Myosin light chain kinase 3 16 46703369-46790407 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040258 Uncertain Tissue enhanced 0 heart muscle: 74.6 skeletal muscle: 16.9 -ABCC12 MRP9 ENSG00000140798 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 16 48082973-48156018 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043100 Uncertain Tissue enhanced 0 testis: 2.9 breast: 0.5 -NKD1 ENSG00000140807 Naked cuticle homolog 1 (Drosophila) 16 50548330-50640739 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041352, HPA049413 Uncertain Approved Nucleoli fibrillar center Mixed smooth muscle: 8.1 -DHX38 DDX38, hPrp16, KIAA0224, PRP16, PRPF16 ENSG00000140829 DEAH (Asp-Glu-Ala-His) box polypeptide 38 16 72093562-72112912 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041347, HPA041604 Uncertain Supported Nucleus Expressed in all parathyroid gland: 49.8 -TXNL4B Dim2, DLP, FLJ20511 ENSG00000140830 Thioredoxin-like 4B 16 72044289-72094431 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065865 Supported Nucleoplasm
Cytosol Expressed in all testis: 28.8 -MARVELD3 MRVLDC3 ENSG00000140832 MARVEL domain containing 3 16 71626161-71642114 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043514, HPA045471 Approved Vesicles
Intermediate filaments Tissue enhanced 0 small intestine: 37.8 duodenum: 32.4 -CHST4 HEC-GLCNAC-6-ST, LSST ENSG00000140835 Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 16 71525233-71538746 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021955 Supported Tissue enriched 13 gallbladder: 102.9 fallopian tube: 7.9 -ZFHX3 ATBF1, ZNF927 ENSG00000140836 Zinc finger homeobox 3 16 72782885-73059698 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059353 Uncertain Supported Nucleoplasm Tissue enhanced 0 parathyroid gland: 28.7 thyroid gland: 12.5 -CLEC18B ENSG00000140839 C-type lectin domain family 18, member B 16 74408270-74421953 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048976 Uncertain Group enriched 10 kidney: 30.8;testis: 8.2 cerebral cortex: 2.0 -CPNE2 CPN2 ENSG00000140848 Copine II 16 57092537-57148367 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041132 Approved Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all lung: 55.7 -NLRC5 CLR16.1, FLJ21709, NOD27 ENSG00000140853 NLR family, CARD domain containing 5 16 56989485-57083531 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059120, HPA060405 Supported Centrosome Mixed spleen: 45.8 -KATNB1 ENSG00000140854 Katanin p80 (WD repeat containing) subunit B 1 16 57735730-57757250 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041165, HPA041839 Supported Supported Plasma membrane
Microtubules
Cytosol Expressed in all testis: 45.4 -KIFC3 ENSG00000140859 Kinesin family member C3 16 57758217-57863053 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021240 Uncertain Expressed in all skin: 98.9 -ADAMTS18 ADAMTS21 ENSG00000140873 ADAM metallopeptidase with thrombospondin type 1 motif, 18 16 77247813-77435114 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA044326 Uncertain Tissue enriched 16 placenta: 28.9 cervix: 1.8 -NUDT7 ENSG00000140876 Nudix (nucleoside diphosphate linked moiety X)-type motif 7 16 77722492-77742260 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042042 Supported Expressed in all liver: 35.7 -GCSH ENSG00000140905 Glycine cleavage system protein H (aminomethyl carrier) 16 81081961-81096403 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041368 Approved Expressed in all thyroid gland: 101.1 -CMTM3 BNAS2, CKLFSF3, FLJ31762 ENSG00000140931 CKLF-like MARVEL transmembrane domain containing 3 16 66603874-66613892 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013870 Approved Nucleoplasm Expressed in all testis: 69.3 -CMTM2 CKLFSF2, FLJ25732, MGC39436 ENSG00000140932 CKLF-like MARVEL transmembrane domain containing 2 16 66579448-66588275 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 1014 testis: 711.4 bone marrow: 0.7 -CDH11 CAD11, OB ENSG00000140937 Cadherin 11, type 2, OB-cadherin (osteoblast) 16 64943753-65126112 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB013072 Approved Tissue enhanced 0 ovary: 223.0 placenta: 172.7 -NOL3 ARC, CARD2, MYP, NOP30 ENSG00000140939 Nucleolar protein 3 (apoptosis repressor with CARD domain) 16 67170154-67175735 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009208 Supported Supported Nucleus
Cytosol Mixed skin: 69.3 -MAP1LC3B ATG8F ENSG00000140941 Microtubule-associated protein 1 light chain 3 beta 16 87383995-87404779 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB037216, HPA043000, HPA052474, HPA052484, HPA053767 Uncertain Supported Microtubule organizing center Expressed in all bone marrow: 122.6 -MBTPS1 KIAA0091, PCSK8, S1P, SKI-1 ENSG00000140943 Membrane-bound transcription factor peptidase, site 1 16 84053761-84116906 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056109 Supported Expressed in all parathyroid gland: 116.3 -CDH13 CDHH ENSG00000140945 Cadherin 13 16 82626803-83800640 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001380, CAB025863 Supported Supported Plasma membrane Tissue enhanced 0 endometrium: 82.5 cervix: 72.5 -ZCCHC14 BDG29, MGC14139 ENSG00000140948 Zinc finger, CCHC domain containing 14 16 87406246-87492045 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA014122 Uncertain Nuclear membrane Expressed in all testis: 61.6 -TLDC1 KIAA1609 ENSG00000140950 TBC/LysM-associated domain containing 1 16 84476421-84554033 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041020 Approved Approved Nucleus
Nucleoli
Cytosol Mixed placenta: 15.4 -ADAD2 FLJ00337, TENRL ENSG00000140955 Adenosine deaminase domain containing 2 16 84191138-84197168 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 43 testis: 32.4 skin: 0.7 -OSGIN1 BDGI, OKL38 ENSG00000140961 Oxidative stress induced growth inhibitor 1 16 83948282-83966332 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019239 Approved Nucleoplasm
Cytosol Tissue enhanced 0 liver: 57.4 duodenum: 32.2 -IRF8 ICSBP, ICSBP1, IRF-8 ENSG00000140968 Interferon regulatory factor 8 16 85898803-85922609 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002267, HPA002531, CAB013480 Supported Validated Nucleoplasm Tissue enhanced 0 lymph node: 302.0;spleen: 209.3;tonsil: 242.0 appendix: 122.6 -RHOT2 ARHT2, C16orf39, MIRO-2 ENSG00000140983 Ras homolog family member T2 16 668086-674174 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012624, HPA012895 Approved Supported Cytosol Expressed in all spleen: 31.7 -RPL3L ENSG00000140986 Ribosomal protein L3-like 16 1943974-1957606 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049136 Supported Approved Nuclear speckles Tissue enriched 6 skeletal muscle: 324.0 heart muscle: 52.6 -ZSCAN32 FLJ20417, ZNF434 ENSG00000140987 Zinc finger and SCAN domain containing 32 16 3382081-3401065 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA005758 Uncertain Approved Nucleoplasm Expressed in all parathyroid gland: 14.4 -RPS2 LLREP3, S2 ENSG00000140988 Ribosomal protein S2 16 1962052-1964860 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055133 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all ovary: 3061.1 -NDUFB10 PDSW ENSG00000140990 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 16 1959508-1961975 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA073189 Supported Expressed in all skeletal muscle: 449.7 -PDPK1 PDK1 ENSG00000140992 3-phosphoinositide dependent protein kinase 1 16 2537964-2603188 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004272, HPA035199, HPA068961 Supported Approved Vesicles Expressed in all parathyroid gland: 51.3 -TIGD7 Sancho ENSG00000140993 Tigger transposable element derived 7 16 3298832-3305729 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041357, HPA041474 Uncertain Supported Plasma membrane
Cytosol Mixed testis: 13.6 -DEF8 FLJ20186 ENSG00000140995 Differentially expressed in FDCP 8 homolog (mouse) 16 89947925-89968060 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041745, HPA049434 Approved Approved Nucleoplasm
Cytosol Expressed in all lymph node: 90.4 -TCF25 KIAA1049, Nulp1 ENSG00000141002 Transcription factor 25 (basic helix-loop-helix) 16 89873586-89911384 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041699, HPA041786 Uncertain Expressed in all cerebral cortex: 124.9 -GALNS GALNAC6S, GAS ENSG00000141012 Galactosamine (N-acetyl)-6-sulfatase 16 88813734-88856970 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026404 Supported Approved Cytosol Expressed in all testis: 29.7 -GAS8 DRC4, GAS11 ENSG00000141013 Growth arrest-specific 8 16 90019629-90044975 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041311, HPA048238 Approved Approved Plasma membrane
Cytosol Mixed fallopian tube: 22.6 -MED9 FLJ10193, MED25 ENSG00000141026 Mediator complex subunit 9 17 17476986-17493226 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056415 Uncertain Approved Nucleoplasm
Midbody Expressed in all parathyroid gland: 22.1 -NCOR1 hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1 ENSG00000141027 Nuclear receptor corepressor 1 17 16029157-16218185 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043246, HPA050288, HPA051168, CAB072830 Supported Validated Nucleoplasm
Cytosol Expressed in all parathyroid gland: 84.0 -COPS3 CSN3, SGN3 ENSG00000141030 COP9 signalosome subunit 3 17 17246820-17281293 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021997, HPA050557 Approved Supported Nucleus
Cytosol Expressed in all testis: 162.3 -GID4 C17orf39, VID24 ENSG00000141034 GID complex subunit 4 homolog 17 18039292-18068404 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044348 Uncertain Approved Cytosol Expressed in all testis: 62.5 -ZNF287 ZKSCAN13, ZSCAN45 ENSG00000141040 Zinc finger protein 287 17 16551387-16569206 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA029290 Uncertain Approved Golgi apparatus Mixed parathyroid gland: 12.8 -MYOCD MYCD ENSG00000141052 Myocardin 17 12665890-12768949 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB046485 Approved Tissue enhanced 0 seminal vesicle: 28.6 smooth muscle: 22.7 -KSR1 KSR, RSU2 ENSG00000141068 Kinase suppressor of ras 1 17 27456714-27626438 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009623, HPA011215 Uncertain Expressed in all placenta: 75.0 -CIRH1A CIRHIN, FLJ14728, KIAA1988, NAIC, TEX292, UTP4 ENSG00000141076 Cirrhosis, autosomal recessive 1A (cirhin) 16 69131291-69231130 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041139, HPA043542 Approved Supported Nucleoli fibrillar center Expressed in all testis: 51.4 -RANBP10 KIAA1464 ENSG00000141084 RAN binding protein 10 16 67723066-67806652 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all bone marrow: 26.8 -CTRL ENSG00000141086 Chymotrypsin-like 16 67927640-67932414 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA034504, HPA034505 Supported Uncertain Nucleoplasm Tissue enriched 209 pancreas: 1630.5 ovary: 7.8 -DPEP3 ENSG00000141096 Dipeptidase 3 16 67975663-67980829 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031870, HPA058607 Supported Tissue enriched 24 testis: 56.8 spleen: 2.3 -GFOD2 FLJ23802, MGC11335 ENSG00000141098 Glucose-fructose oxidoreductase domain containing 2 16 67674531-67719421 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040939, HPA041112 Uncertain Supported Nucleoplasm
Cytosol Expressed in all esophagus: 22.8 -NOB1 ART-4, MST158, NOB1P, PSMD8BP1 ENSG00000141101 NIN1/RPN12 binding protein 1 homolog 16 69741867-69754940 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041522, HPA049430, HPA067411 Approved Approved Focal adhesion sites
Cytosol Expressed in all fallopian tube: 69.0 -PRPSAP2 PAP41 ENSG00000141127 Phosphoribosyl pyrophosphate synthetase-associated protein 2 17 18840085-18931287 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021881 Approved Approved Nucleoplasm
Cytosol Expressed in all lymph node: 62.0 -UNC45B CMYA4, UNC45 ENSG00000141161 Unc-45 myosin chaperone B 17 35147817-35189345 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017861 Uncertain Supported Cytosol Group enriched 26 heart muscle: 63.7;skeletal muscle: 68.0 prostate: 2.5 -PCTP STARD2 ENSG00000141179 Phosphatidylcholine transfer protein 17 55750979-55842830 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022979 Approved Approved Nucleus
Nucleoli Expressed in all liver: 49.2 -OR4D1 OR4D3, TPCR16 ENSG00000141194 Olfactory receptor, family 4, subfamily D, member 1 17 58155133-58156156 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.1 -TOM1L1 SRCASM ENSG00000141198 Target of myb1 like 1 membrane trafficking protein 17 54899387-54961956 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022916 Uncertain Mixed duodenum: 118.8 -KIF2B ENSG00000141200 Kinesin family member 2B 17 53822901-53825213 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023081, HPA023103, HPA024795 Uncertain Approved Nucleus
Nucleoli
Microtubules Tissue enriched 1324 testis: 132.4 epididymis: 0.0 -C17orf80 FLJ20721, HLC-8, MIG3, SPEP1 ENSG00000141219 Chromosome 17 open reading frame 80 17 73232233-73248947 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA012896 Uncertain Approved Nucleoplasm
Vesicles Expressed in all testis: 71.6 -TOB1 TOB, TROB, TROB1 ENSG00000141232 Transducer of ERBB2, 1 17 50862223-50867978 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047839 Approved Approved Nucleoplasm
Vesicles Expressed in all adrenal gland: 280.3 -VPS53 FLJ10979, HCCS1 ENSG00000141252 Vacuolar protein sorting 53 homolog (S. cerevisiae) 17 508668-721717 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022988, HPA024446 Approved Approved Golgi apparatus
Cytosol Expressed in all cerebral cortex: 18.7 -SPATA22 NYD-SP20 ENSG00000141255 Spermatogenesis associated 22 17 3440019-3513852 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 81 testis: 413.3 placenta: 5.1 -SGSM2 KIAA0397, RUTBC1 ENSG00000141258 Small G protein signaling modulator 2 17 2337498-2381058 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021641, HPA024553 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 78.2 -NPEPPS MP100, PSA ENSG00000141279 Aminopeptidase puromycin sensitive 17 47522942-47623276 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021453, HPA045649 Uncertain Supported Cytosol Expressed in all esophagus: 107.3 -SKAP1 SCAP1, SKAP55 ENSG00000141293 Src kinase associated phosphoprotein 1 17 48133440-48430275 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002969, CAB025882, CAB055513 Supported Mixed lymph node: 34.1 -LRRC46 MGC16309 ENSG00000141294 Leucine rich repeat containing 46 17 47831627-47837713 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021882 Approved Cytosol Group enriched 13 fallopian tube: 119.1;testis: 55.5 lung: 6.5 -SCRN2 ENSG00000141295 Secernin 2 17 47837692-47841333 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022934, HPA023434 Supported Supported Nucleoplasm
Golgi apparatus Expressed in all adipose tissue: 84.2 -SSH2 KIAA1725 ENSG00000141298 Slingshot protein phosphatase 2 17 29625938-29930276 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017189, HPA057099 Approved Expressed in all bone marrow: 35.8 -RHBDL3 RHBDL4, VRHO ENSG00000141314 Rhomboid, veinlet-like 3 (Drosophila) 17 32266176-32324661 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059607 Uncertain Tissue enhanced 0 cerebral cortex: 20.7 adrenal gland: 5.5 -SPACA3 ALLP17, CT54, LYC3, LYZL3, SLLP1 ENSG00000141316 Sperm acrosome associated 3 17 32970376-32997877 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023633 Supported Tissue enriched 17 testis: 77.2 pancreas: 4.5 -ARSG KIAA1001 ENSG00000141337 Arylsulfatase G 17 68259182-68422731 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023245, HPA023285 Approved Tissue enhanced 0 epididymis: 47.8 thyroid gland: 18.9 -ABCA8 KIAA0822 ENSG00000141338 ATP-binding cassette, sub-family A (ABC1), member 8 17 68867292-68955392 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044914 Approved Approved Nucleoplasm
Cytosol Mixed ovary: 67.2 -G6PC3 UGRP ENSG00000141349 Glucose 6 phosphatase, catalytic, 3 17 44070735-44076344 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067052 Supported Endoplasmic reticulum Expressed in all epididymis: 82.8 -CLTC CLTCL2, Hc ENSG00000141367 Clathrin, heavy chain (Hc) 17 59619689-59696956 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010389, CAB011571, CAB017155, HPA059143 Approved Validated Endosomes
Lysosomes Expressed in all parathyroid gland: 358.1 -C17orf64 ENSG00000141371 Chromosome 17 open reading frame 64 17 60392429-60431421 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044415 Supported Approved Nucleoplasm
Vesicles Tissue enriched 227 testis: 184.8 spleen: 0.8 -BCAS3 FLJ20128 ENSG00000141376 Breast carcinoma amplified sequence 3 17 60677453-61392838 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052409, HPA057289 Approved Supported Nucleoli Expressed in all parathyroid gland: 32.5 -PTRH2 BIT1, CFAP37, CGI-147, PTH2 ENSG00000141378 Peptidyl-tRNA hydrolase 2 17 59674636-59707626 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012897 Supported Supported Mitochondria Expressed in all epididymis: 43.1 -SS18 SSXT, SYT ENSG00000141380 Synovial sarcoma translocation, chromosome 18 18 26016253-26091217 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055741, HPA059539 Supported Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 74.4 -TAF4B TAF2C2, TAFII105 ENSG00000141384 TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 18 26225936-26391685 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028937 Uncertain Supported Nucleoplasm
Nucleoli fibrillar center Mixed testis: 4.3 -AFG3L2 SCA28, SPAX5 ENSG00000141385 AFG3-like AAA ATPase 2 18 12328944-12377314 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004479, HPA004480 Supported Validated Mitochondria Expressed in all parathyroid gland: 121.6 -PRELID3A C18orf43, FLJ31484, HFL-EDDG1, SLMO1 ENSG00000141391 PRELI domain containing 3A 18 12407896-12432238 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed seminal vesicle: 16.9 -IMPA2 ENSG00000141401 Inositol(myo)-1(or 4)-monophosphatase 2 18 11981025-12030883 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029561 Approved Approved Nucleoplasm
Mitochondria Expressed in all skin: 129.8 -GNAL ENSG00000141404 Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 18 11688956-11885685 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015464 Uncertain Approved Nucleus
Cytosol Mixed cerebral cortex: 28.9 -SLC39A6 LIV-1 ENSG00000141424 Solute carrier family 39 (zinc transporter), member 6 18 36108532-36129385 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042377 Approved Expressed in all prostate: 209.0 -RPRD1A FLJ10656, HsT3101, P15RS ENSG00000141425 Regulation of nuclear pre-mRNA domain containing 1A 18 35984387-36067576 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040602 Supported Supported Nucleus
Golgi apparatus Expressed in all epididymis: 138.0 -C18orf21 HsT3108, PNAS-124, PNAS-131 ENSG00000141428 Chromosome 18 open reading frame 21 18 35972083-35979286 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065505, HPA067322 Uncertain Approved Nucleoli
Plasma membrane Expressed in all testis: 59.3 -GALNT1 GalNAc-T1 ENSG00000141429 Polypeptide N-acetylgalactosaminyltransferase 1 18 35581117-35711834 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012628 Uncertain Expressed in all urinary bladder: 88.7 -ASXL3 KIAA1713 ENSG00000141431 Additional sex combs like transcriptional regulator 3 18 33578615-33751192 Disease related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039539, HPA040034 Uncertain Tissue enhanced 0 ovary: 3.6 cerebral cortex: 2.8 -ADCYAP1 PACAP ENSG00000141433 Adenylate cyclase activating polypeptide 1 (pituitary) 18 904943-912172 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA065887 Approved Tissue enhanced 0 appendix: 19.7;cerebral cortex: 16.1;gallbladder: 15.7 testis: 5.7 -MEP1B ENSG00000141434 Meprin A, beta 18 32185069-32220404 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029119 Supported Group enriched 34 duodenum: 258.3;small intestine: 410.0 colon: 9.9 -SLC25A52 MCART2 ENSG00000141437 Solute carrier family 25, member 52 18 31759562-31760880 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA046388, HPA058261 Uncertain Approved Mitochondria Tissue enriched 104 testis: 15.3 breast: 0.1 -GAREM C18orf11, FAM59A, FLJ21610 ENSG00000141441 GRB2 associated, regulator of MAPK1 18 32124877-32470484 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040709, HPA042046 Approved Approved Nucleoplasm
Cytosol Mixed cerebral cortex: 13.8 -ESCO1 EFO1, ESO1, KIAA1911 ENSG00000141446 Establishment of sister chromatid cohesion N-acetyltransferase 1 18 21529281-21600884 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042497 Approved Expressed in all testis: 36.4 -OSBPL1A ORP-1, ORP1, OSBPL1B ENSG00000141447 Oxysterol binding protein-like 1A 18 24162044-24397880 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040959, HPA043401 Supported Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 130.4 -GATA6 ENSG00000141448 GATA binding protein 6 18 22169443-22202528 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011581, HPA066629 Uncertain Supported Nucleus Mixed adrenal gland: 51.1 -GREB1L C18orf6, FLJ13687, KIAA1772 ENSG00000141449 Growth regulation by estrogen in breast cancer-like 18 21242242-21525417 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041647, HPA044218 Uncertain Approved Nucleoli
Mitochondria Tissue enhanced 0 testis: 11.4 thyroid gland: 5.8 -C18orf8 HsT2591, MIC-1, MIC1 ENSG00000141452 Chromosome 18 open reading frame 8 18 23503470-23531807 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043589 Uncertain Uncertain Nucleus Expressed in all testis: 33.0 -PELP1 MNAR ENSG00000141456 Proline, glutamate and leucine rich protein 1 17 4669774-4704337 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053966, HPA056028, HPA060760 Supported Validated Nucleus
Nucleoli Expressed in all testis: 35.4 -NPC1 ENSG00000141458 Niemann-Pick disease, type C1 18 23506184-23586898 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026618, CAB070132 Approved Expressed in all parathyroid gland: 110.9 -SLC14A1 HsT1341, JK, RACH1, RACH2 ENSG00000141469 Solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 18 45724127-45752520 Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058353, HPA059570 Supported Supported Vesicles Group enriched 5 prostate: 132.1;urinary bladder: 51.9 cerebral cortex: 18.2 -ARRB2 ARR2, BARR2, DKFZp686L0365 ENSG00000141480 Arrestin, beta 2 17 4710489-4721499 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065681 Supported Vesicles Expressed in all bone marrow: 171.8 -SLC13A5 NACT ENSG00000141485 Solute carrier family 13 (sodium-dependent citrate transporter), member 5 17 6684713-6713567 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044343, HPA057088 Approved Uncertain Nucleoplasm Tissue enriched 9 liver: 118.1 salivary gland: 12.8 -ZMYND15 DKFZp434N127 ENSG00000141497 Zinc finger, MYND-type containing 15 17 4740015-4746119 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA023286 Approved Nuclear speckles
Cytosol Tissue enhanced 0 parathyroid gland: 15.6;testis: 29.5 lung: 7.6 -WRAP53 FLJ10385, TCAB1, WDR79 ENSG00000141499 WD repeat containing, antisense to TP53 17 7686071-7703502 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023026, HPA028130, HPA029928 Supported Validated Nucleoplasm
Nuclear bodies
Cytosol Mixed fallopian tube: 21.6 -MINK1 B55, MAP4K6, MINK, YSK2, ZC3 ENSG00000141503 Misshapen-like kinase 1 17 4833388-4898061 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056296 Approved Expressed in all skin: 72.6 -SAT2 SSAT2 ENSG00000141504 Spermidine/spermine N1-acetyltransferase family member 2 17 7626234-7627876 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022136, HPA057096 Supported Expressed in all duodenum: 93.5 -ASGR1 CLEC4H1 ENSG00000141505 Asialoglycoprotein receptor 1 17 7173431-7179564 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011954, HPA012852 Supported Supported Vesicles
Cell Junctions Tissue enriched 13 liver: 236.1 testis: 17.7 -PIK3R5 p101, P101-PI3K ENSG00000141506 Phosphoinositide-3-kinase, regulatory subunit 5 17 8878911-8965712 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044505, HPA052247, HPA052412 Uncertain Supported Microtubule organizing center
Cytosol Tissue enhanced 0 bone marrow: 55.2 spleen: 28.4 -TP53 LFS1, p53 ENSG00000141510 Tumor protein p53 17 7661779-7687550 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002973, CAB039238, CAB039239, HPA051244, CAB072876 Supported Validated Nucleoplasm Expressed in all fallopian tube: 50.3 -CCDC40 CILD15, FAP172, FLJ20753, FLJ32021, KIAA1640 ENSG00000141519 Coiled-coil domain containing 40 17 80036632-80100613 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA022974 Uncertain Approved Microtubules Tissue enhanced 0 fallopian tube: 23.5 testis: 12.9 -ARHGDIA GDIA1, RHOGDI ENSG00000141522 Rho GDP dissociation inhibitor (GDI) alpha 17 81867721-81871406 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010005, HPA021407 Approved Validated Cytosol Expressed in all appendix: 213.0 -TMC6 EVER1, EVIN1, LAK-4P ENSG00000141524 Transmembrane channel-like 6 17 78110458-78132407 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051430 Uncertain Expressed in all spleen: 84.5 -SLC16A3 MCT3, MCT4 ENSG00000141526 Solute carrier family 16 (monocarboxylate transporter), member 3 17 82228397-82261129 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017490, HPA021451 Approved Supported Nuclear membrane
Plasma membrane Expressed in all skeletal muscle: 74.4 -CARD14 BIMP2, CARMA2, PSORS2 ENSG00000141527 Caspase recruitment domain family, member 14 17 80169992-80209331 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skin: 17.8 esophagus: 7.0 -TTYH2 C17orf29 ENSG00000141540 Tweety family member 2 17 74213514-74262020 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 cerebral cortex: 129.6 testis: 21.8 -RAB40B RAR, SEC4L ENSG00000141542 RAB40B, member RAS oncogene family 17 82654973-82698728 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 56.9 epididymis: 17.8 -EIF4A3 DDX48, EIF4AIII, KIAA0111 ENSG00000141543 Eukaryotic translation initiation factor 4A3 17 80135214-80147183 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021878 Supported Supported Nucleoplasm Expressed in all bone marrow: 112.3 -CSNK1D CKID, CKIdelta, HCKID ENSG00000141551 Casein kinase 1, delta 17 82239023-82273731 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015410 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all cerebral cortex: 67.1 -ANAPC11 APC11, Apc11p, HSPC214, MGC882 ENSG00000141552 Anaphase promoting complex subunit 11 17 81890790-81900991 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA021989, HPA027838 Approved Validated Nucleoplasm
Nucleoli Expressed in all testis: 110.3 -TBCD ENSG00000141556 Tubulin folding cofactor D 17 82752064-82945922 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045200 Approved Expressed in all thyroid gland: 58.5 -FN3KRP FLJ12171, FN3KL ENSG00000141560 Fructosamine 3 kinase related protein 17 82716683-82730328 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056172, HPA065831 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 49.0 -NARF DKFZp434G0420, FLJ10067, IOP2 ENSG00000141562 Nuclear prelamin A recognition factor 17 82458180-82490537 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053006 Supported Nucleus
Nucleoli Expressed in all testis: 47.2 -RPTOR KIAA1303, KOG1, Mip1, raptor ENSG00000141564 Regulatory associated protein of MTOR, complex 1 17 80544819-80966371 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013514, HPA064306 Approved Validated Nucleoplasm
Lysosomes
Cytosol Mixed cerebral cortex: 11.2 -FOXK2 ILF, ILF1 ENSG00000141568 Forkhead box K2 17 82519713-82644662 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027523 Approved Supported Nucleoplasm
Vesicles Expressed in all testis: 64.8 -TRIM65 ENSG00000141569 Tripartite motif containing 65 17 75880335-75897003 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021575, HPA021578, HPA064820 Approved Supported Nucleoplasm
Vesicles
Cytosol Expressed in all skin: 20.4 -CBX8 HPC3, PC3, RC1 ENSG00000141570 Chromobox homolog 8 17 79792132-79801683 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031462 Approved Validated Nucleoplasm Mixed epididymis: 13.5 -SECTM1 K12 ENSG00000141574 Secreted and transmembrane 1 17 82321024-82334074 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051214 Approved Tissue enhanced 0 small intestine: 98.6 duodenum: 66.3 -RNF157 KIAA1917 ENSG00000141576 Ring finger protein 157 17 76142453-76240373 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA021854, HPA021991, HPA023922 Uncertain Approved Golgi apparatus
Vesicles Tissue enhanced 0 cerebral cortex: 60.8;testis: 58.1 skeletal muscle: 24.9 -CEP131 AZ1, AZI1, KIAA1118 ENSG00000141577 Centrosomal protein 131kDa 17 81189593-81222999 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024019 Approved Supported Microtubules
Cytokinetic bridge
Microtubule organizing center Mixed testis: 17.3 -ZNF750 FLJ13841, Zfp750 ENSG00000141579 Zinc finger protein 750 17 82829435-82840578 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA021573, HPA023012 Approved Approved Nucleus
Nucleoli
Vesicles Tissue enhanced 0 esophagus: 60.7;skin: 54.5 salivary gland: 13.0 -WDR45B WDR45L, WIPI3 ENSG00000141580 WD repeat domain 45B 17 82614562-82648553 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA017886 Approved Nucleus
Golgi apparatus
Cytosol Expressed in all testis: 82.9 -CBX4 hPC2, NBP16, PC2 ENSG00000141582 Chromobox homolog 4 17 79833156-79839429 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008228, HPA012021 Approved Validated Nucleoplasm
Nuclear bodies Tissue enhanced 0 bone marrow: 85.3 cerebral cortex: 25.7 -RNF165 ARKL2, RNF111L2 ENSG00000141622 Ring finger protein 165 18 46326809-46463140 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041615, HPA047798 Uncertain Approved Nucleus
Plasma membrane Tissue enhanced 0 cerebral cortex: 9.3;parathyroid gland: 9.6 thyroid gland: 6.9 -DYM DMC, FLJ20071, SMC ENSG00000141627 Dymeclin 18 49041474-49461347 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043551, HPA049187 Approved Supported Golgi apparatus Expressed in all testis: 79.7 -MAPK4 Erk3-related, Erk4, PRKM4 ENSG00000141639 Mitogen-activated protein kinase 4 18 50560078-50731824 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adrenal gland: 29.9;cerebral cortex: 33.5;parathyroid gland: 59.0 seminal vesicle: 13.7 -ELAC1 D29 ENSG00000141642 ElaC ribonuclease Z 1 18 50967991-50988121 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040867, HPA066483 Approved Supported Nucleus
Cytosol Expressed in all parathyroid gland: 17.9 -MBD1 CXXC3, PCM1 ENSG00000141644 Methyl-CpG binding domain protein 1 18 50266882-50281774 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009017, CAB036003 Approved Supported Nucleus Expressed in all testis: 109.0 -SMAD4 DPC4, MADH4 ENSG00000141646 SMAD family member 4 18 51028394-51085045 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019154 Approved Supported Nucleoplasm
Centrosome
Cytosol Expressed in all parathyroid gland: 38.7 -TNFRSF11A CD265, FEO, LOH18CR1, PDB2, RANK ENSG00000141655 Tumor necrosis factor receptor superfamily, member 11a, NFKB activator 18 62325287-62391292 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB010391, HPA027728, HPA047976 Uncertain Supported Plasma membrane
Cytosol Tissue enhanced 0 duodenum: 31.2 small intestine: 20.9 -ZCCHC2 C18orf49, FLJ20222, FLJ20281, KIAA1744 ENSG00000141664 Zinc finger, CCHC domain containing 2 18 62523007-62587709 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040943 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all testis: 22.3 -FBXO15 FBX15, MGC39671 ENSG00000141665 F-box protein 15 18 74073353-74147865 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 4.8;testis: 6.6 epididymis: 2.0 -CBLN2 ENSG00000141668 Cerebellin 2 precursor 18 72536680-72638521 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056335 Uncertain Endoplasmic reticulum Group enriched 7 cerebral cortex: 30.3;seminal vesicle: 7.2 small intestine: 2.8 -PMAIP1 APR, NOXA ENSG00000141682 Phorbol-12-myristate-13-acetate-induced protein 1 18 59899948-59904306 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051063 Uncertain Approved Vesicles Tissue enhanced 0 bone marrow: 55.9 placenta: 18.3 -P3H4 LEPREL4, NO55, SC65 ENSG00000141696 Prolyl 3-hydroxylase family member 4 (non-enzymatic) 17 41801947-41812604 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed thyroid gland: 18.3 -NT5C3B MGC20781, NT5C3L ENSG00000141698 5'-nucleotidase, cytosolic IIIB 17 41825181-41836263 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030786, HPA057095 Approved Expressed in all thyroid gland: 79.0 -FAM134C DKFZp686B1036, FLJ33806 ENSG00000141699 Family with sequence similarity 134, member C 17 42579513-42610623 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016492 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all testis: 48.6 -ERBB2 CD340, HER-2, HER2, NEU, NGL ENSG00000141736 Erb-b2 receptor tyrosine kinase 2 17 39687914-39730426 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555 Approved Supported Plasma membrane
Cytosol Expressed in all parathyroid gland: 122.9 -GRB7 ENSG00000141738 Growth factor receptor-bound protein 7 17 39737927-39747291 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005226, HPA057084, CAB073538 Approved Supported Plasma membrane Mixed fallopian tube: 34.9 -MIEN1 C17orf37, C35, MGC14832, ORB3, Rdx12, XTP4 ENSG00000141741 Migration and invasion enhancer 1 17 39728496-39730787 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061344 Approved Expressed in all cerebral cortex: 40.8 -PNMT PENT ENSG00000141744 Phenylethanolamine N-methyltransferase 17 39667981-39670475 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017029, HPA043412, HPA051005 Supported Uncertain Vesicles Tissue enriched 8 adrenal gland: 227.7 seminal vesicle: 28.8 -ARL5C ARL12 ENSG00000141748 ADP-ribosylation factor-like 5C 17 39156894-39167484 Predicted intracellular proteins No evidence No evidence No evidence HPA069849 Uncertain Not detected lymph node: 0.4 -STAC2 24b2 ENSG00000141750 SH3 and cysteine rich domain 2 17 39210536-39225872 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017288 Approved Nucleoplasm
Vesicles Group enriched 6 breast: 31.7;cerebral cortex: 30.2;epididymis: 14.8;seminal vesicle: 35.5 skin: 4.5 -IGFBP4 BP-4, HT29-IGFBP, IBP4, IGFBP-4 ENSG00000141753 Insulin-like growth factor binding protein 4 17 40443461-40457731 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066240 Supported Expressed in all smooth muscle: 923.3 -FKBP10 FKBP6, FLJ20683, FLJ22041, FLJ23833, hFKBP65 ENSG00000141756 FK506 binding protein 10, 65 kDa 17 41812680-41823217 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051171, HPA057021 Approved Approved Vesicles Mixed placenta: 84.2 -TXNL4A DIB1, DIM1, HsT161, SNRNP15, TXNL4, U5-15kD ENSG00000141759 Thioredoxin-like 4A 18 79970811-80033949 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041324 Approved Nucleus
Nuclear membrane
Cytosol Expressed in all cerebral cortex: 82.7 -CACNA1A APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6 ENSG00000141837 Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 19 13206442-13623990 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064258 Supported Approved Nucleoplasm
Golgi apparatus
Vesicles Tissue enhanced 0 cerebral cortex: 18.1 stomach: 6.4 -CTB-55O6.8 ENSG00000141854 Uncharacterized protein LOC113230 19 14072536-14075062 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042225 Uncertain Mixed small intestine: 8.7 -SAMD1 ENSG00000141858 Sterile alpha motif domain containing 1 19 14087840-14091036 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041662, HPA049059 Uncertain Approved Mitochondria
Cytosol Expressed in all cerebral cortex: 32.3 -BRD4 CAP, HUNK1, HUNKI, MCAP ENSG00000141867 Bromodomain containing 4 19 15235519-15332545 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015055, HPA061646, CAB068177, CAB068178 Supported Validated Nucleoplasm Expressed in all placenta: 41.6 -SLC39A3 ZIP3 ENSG00000141873 Solute carrier family 39 (zinc transporter), member 3 19 2732204-2740152 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042139, HPA058526 Uncertain Approved Vesicles Expressed in all testis: 109.9 -NFIC CTF, CTF5, NF-I, NFI ENSG00000141905 Nuclear factor I/C (CCAAT-binding transcription factor) 19 3359563-3469217 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004300, CAB004674, HPA052625 Supported Validated Nucleus
Nucleoli fibrillar center Expressed in all skeletal muscle: 68.9 -TPGS1 C19orf20, GTRGEO22, PGs1 ENSG00000141933 Tubulin polyglutamylase complex subunit 1 19 507497-519654 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed cerebral cortex: 6.6 -PLPP2 LPP2, PAP-2c, PPAP2C ENSG00000141934 Phospholipid phosphatase 2 19 281040-291504 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055540 Uncertain Approved Mitochondria Tissue enhanced 0 fallopian tube: 126.8 cervix: 91.2 -ZIM3 ZNF657 ENSG00000141946 Zinc finger, imprinted 3 19 57134096-57145202 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA034575 Uncertain Not detected testis: 0.8 -PRDM15 C21orf83, ZNF298 ENSG00000141956 PR domain containing 15 21 41798225-41879482 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024268, HPA029255, HPA029256 Uncertain Supported Nucleoplasm
Nuclear bodies Mixed lymph node: 8.9 -PFKL ENSG00000141959 Phosphofructokinase, liver 21 44300051-44327376 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030047 Approved Approved Nucleoli
Mitochondria Expressed in all small intestine: 103.8 -FEM1A ENSG00000141965 Fem-1 homolog a (C. elegans) 19 4791681-4801273 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016565, HPA063622 Supported Nucleus
Golgi apparatus
Cytosol Tissue enriched 7 skeletal muscle: 94.0 parathyroid gland: 13.5 -VAV1 VAV ENSG00000141968 Vav 1 guanine nucleotide exchange factor 19 6772714-6857366 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001864 Supported Approved Cytosol Tissue enhanced 0 lymph node: 58.4 appendix: 54.5 -MVB12A FAM125A, FLJ32495 ENSG00000141971 Multivesicular body subunit 12A 19 17405722-17433724 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041885, HPA042231 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all ovary: 38.0 -CIB3 KIP3 ENSG00000141977 Calcium and integrin binding family member 3 19 16161368-16173525 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043553 Uncertain Not detected bone marrow: 0.8 -SH3GL1 CNSA1, EEN, MGC111371, SH3D2B, SH3P8 ENSG00000141985 SH3-domain GRB2-like 1 19 4360370-4400547 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021485 Approved Validated Cytosol Expressed in all esophagus: 115.0 -DUS3L DUS3, FLJ13896 ENSG00000141994 Dihydrouridine synthase 3-like 19 5784832-5791238 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041854, HPA041944, HPA062846 Uncertain Approved Nucleoplasm
Cytosol Expressed in all testis: 26.8 -DPP9 ENSG00000142002 Dipeptidyl-peptidase 9 19 4675224-4724673 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036059 Approved Supported Cytosol Expressed in all appendix: 34.2 -DMRTC2 ENSG00000142025 DMRT-like family C2 19 41844743-41852333 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045016 Uncertain Tissue enriched 127 testis: 48.7 parathyroid gland: 0.3 -CCDC97 FLJ40267, MGC20255 ENSG00000142039 Coiled-coil domain containing 97 19 41310189-41324883 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043320, HPA043572 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 58.7 -TMEM91 FLJ27310, IFITMD6 ENSG00000142046 Transmembrane protein 91 19 41350911-41384083 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053240 Uncertain Expressed in all skin: 31.0 -ZFP14 KIAA1559, ZNF531 ENSG00000142065 ZFP14 zinc finger protein 19 36334453-36379199 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030637 Uncertain Approved Nuclear speckles Mixed parathyroid gland: 8.6 -SIRT3 SIR2L3 ENSG00000142082 Sirtuin 3 11 215458-236931 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026809, CAB037142 Approved Expressed in all epididymis: 49.8 -IFITM3 1-8U ENSG00000142089 Interferon induced transmembrane protein 3 11 319669-327537 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004337 Uncertain Expressed in all fallopian tube: 1027.4 -ATHL1 FLJ22635 ENSG00000142102 ATH1, acid trehalase-like 1 (yeast) 11 289135-296107 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039383, HPA058829 Uncertain Validated Cytosol Expressed in all lymph node: 74.8 -HUNK ENSG00000142149 Hormonally up-regulated Neu-associated kinase 21 31873315-32044633 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027295, HPA027372 Approved Approved Nucleoplasm
Plasma membrane Mixed placenta: 6.8 -COL6A1 ENSG00000142156 Collagen, type VI, alpha 1 21 45981737-46005050 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019142, HPA029401 Supported Approved Cytosol Mixed placenta: 400.7 -IFNAR1 IFNAR, IFRC ENSG00000142166 Interferon (alpha, beta and omega) receptor 1 21 33324477-33359862 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018015, HPA029226 Approved Approved Cytosol Expressed in all parathyroid gland: 60.2 -SOD1 ALS, ALS1, IPOA ENSG00000142168 Superoxide dismutase 1, soluble 21 31659622-31668931 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001401, CAB008670 Supported Supported Nucleus
Plasma membrane
Cytosol Expressed in all liver: 767.7 -COL6A2 ENSG00000142173 Collagen, type VI, alpha 2 21 46098097-46132849 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007029, HPA030920, HPA038799 Supported Approved Plasma membrane
Cytosol Expressed in all placenta: 470.8 -SIK1 msk, SNF1LK ENSG00000142178 Salt-inducible kinase 1 21 43414515-43427128 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB023801, HPA038211 Approved Supported Cytosol Mixed seminal vesicle: 13.8 -DNMT3L MGC1090 ENSG00000142182 DNA (cytosine-5-)-methyltransferase 3-like 21 44246339-44262216 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA055234, HPA066780 Uncertain Approved Nuclear speckles Group enriched 6 kidney: 7.4;liver: 10.8;lymph node: 2.3 spleen: 1.1 -TRPM2 EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7 ENSG00000142185 Transient receptor potential cation channel, subfamily M, member 2 21 44350163-44443081 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030976, HPA035260 Approved Approved Nuclear membrane Mixed bone marrow: 18.9 -SCYL1 GKLP, HT019, MGC78454, NKTL, NTKL, P105, TAPK, TEIF, TRAP ENSG00000142186 SCY1-like, kinase-like 1 11 65525077-65538704 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015015 Uncertain Supported Cytosol Expressed in all thyroid gland: 55.0 -TMEM50B C21orf4 ENSG00000142188 Transmembrane protein 50B 21 33432485-33480011 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034199, HPA068995 Approved Approved Nucleoli fibrillar center Expressed in all thyroid gland: 74.3 -APP AD1 ENSG00000142192 Amyloid beta (A4) precursor protein 21 25880550-26171128 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000157, HPA001462 Supported Approved Golgi apparatus
Vesicles Expressed in all cerebral cortex: 1206.8 -DOPEY2 C21orf5, KIAA0933 ENSG00000142197 Dopey family member 2 21 36156782-36294274 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB034922, HPA072065 Approved Approved Nucleoplasm
Mitochondria Expressed in all parathyroid gland: 83.9 -URB1 C21orf108, KIAA0539, NPA1 ENSG00000142207 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 21 32311018-32393026 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018334 Supported Supported Nucleoli fibrillar center Mixed endometrium: 12.0 -AKT1 AKT, PKB, PRKBA, RAC ENSG00000142208 V-akt murine thymoma viral oncogene homolog 1 14 104769349-104795751 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002891, CAB003765 Supported Supported Nucleus
Microtubules Expressed in all lung: 104.6 -IL19 IL-10C, IL-19, MDA1, NG.1, ZMDA1 ENSG00000142224 Interleukin 19 1 206798870-206842981 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 9 cervix, uterine: 20.8 salivary gland: 2.3 -EMP3 YMP ENSG00000142227 Epithelial membrane protein 3 19 48321509-48330553 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051163 Approved Nuclear bodies Expressed in all smooth muscle: 199.1 -SAE1 AOS1, FLJ3091, Sua1 ENSG00000142230 SUMO1 activating enzyme subunit 1 19 47113274-47210636 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041906, HPA043552 Supported Expressed in all testis: 145.1 -NTN5 ENSG00000142233 Netrin 5 19 48661407-48673081 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed endometrium: 1.5 -LMTK3 KIAA1883, LMR3, PPP1R101, TYKLM3 ENSG00000142235 Lemur tyrosine kinase 3 19 48485271-48513189 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040203 Approved Nucleoplasm
Cell Junctions Group enriched 5 cerebral cortex: 20.4;parathyroid gland: 4.8 duodenum: 2.3 -GEMIN7 FLJ13956 ENSG00000142252 Gem (nuclear organelle) associated protein 7 19 45079195-45091524 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052075 Supported Nucleus
Cytosol Expressed in all lymph node: 30.8 -CBLC CBL-3, CBL-SL, RNF57 ENSG00000142273 Cbl proto-oncogene C, E3 ubiquitin protein ligase 19 44777869-44800634 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB008087, HPA035266 Approved Approved Nucleoplasm Tissue enhanced 0 duodenum: 53.9;skin: 42.0;small intestine: 44.9 colon: 21.8 -WTIP ENSG00000142279 Wilms tumor 1 interacting protein 19 34481638-34512304 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed ovary: 34.2 -ADAMTS10 ADAM-TS10 ENSG00000142303 ADAM metallopeptidase with thrombospondin type 1 motif, 10 19 8580242-8610735 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040223 Uncertain Approved Cytosol Mixed endometrium: 5.9 -SLC6A3 DAT, DAT1 ENSG00000142319 Solute carrier family 6 (neurotransmitter transporter), member 3 5 1392790-1445430 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level No evidence Evidence at protein level HPA013602, CAB016249, CAB078172 Uncertain Supported Approved Vesicles Not detected thyroid gland: 0.3 -RNPEPL1 ENSG00000142327 Arginyl aminopeptidase (aminopeptidase B)-like 1 2 240565804-240581372 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036772 Uncertain Approved Nucleus
Nucleoli Expressed in all skin: 29.4 -CAPN10 ENSG00000142330 Calpain 10 2 240586716-240617705 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA004170, HPA056098 Approved Approved Nucleoplasm
Cytosol Expressed in all spleen: 15.5 -MYO1F ENSG00000142347 Myosin IF 19 8520790-8577577 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055242 Supported Tissue enhanced 0 appendix: 51.6;bone marrow: 59.8;spleen: 64.4 lung: 23.4 -ERVK3-1 HERV-K(HML6-1) ENSG00000142396 Endogenous retrovirus group K3, member 1 19 58305319-58315663 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Expressed in all breast: 49.7 -NLRP12 CLR19.3, Monarch1, NALP12, PAN6, PYPAF7, RNO2 ENSG00000142405 NLR family, pyrin domain containing 12 19 53793603-53824394 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042981 Approved Tissue enhanced 0 appendix: 3.1;bone marrow: 4.1 spleen: 2.2 -CACNG8 ENSG00000142408 Calcium channel, voltage-dependent, gamma subunit 8 19 53963040-53990215 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041351 Supported Tissue enriched 32 cerebral cortex: 23.8 testis: 0.7 -ZNF787 ENSG00000142409 Zinc finger protein 787 19 56087366-56121280 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035140 Supported Approved Nucleus
Nucleoli
Mitochondria Expressed in all spleen: 19.7 -C19orf52 ENSG00000142444 Chromosome 19 open reading frame 52 19 10928733-10933535 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041858 Approved Approved Nucleoplasm
Mitochondria Expressed in all duodenum: 7.6 -FBN3 ENSG00000142449 Fibrillin 3 19 8065402-8149846 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049482 Uncertain Tissue enhanced 0 lung: 2.1;thyroid gland: 1.7 salivary gland: 1.1 -CARM1 PRMT4 ENSG00000142453 Coactivator-associated arginine methyltransferase 1 19 10871513-10923070 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032961, HPA043561, HPA048073 Supported Validated Nucleoplasm Expressed in all skeletal muscle: 37.1 -EVI5L ENSG00000142459 Ecotropic viral integration site 5-like 19 7830233-7864976 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043099, HPA043563 Approved Approved Nuclear bodies Expressed in all cerebral cortex: 41.7 -TM4SF5 ENSG00000142484 Transmembrane 4 L six family member 5 17 4771884-4783213 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055674 Uncertain Nucleoplasm
Plasma membrane
Cell Junctions Group enriched 5 duodenum: 181.8;small intestine: 172.8 liver: 33.2 -SLC47A1 FLJ10847, MATE1 ENSG00000142494 Solute carrier family 47 (multidrug and toxin extrusion), member 1 17 19495385-19579034 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021987 Supported Tissue enhanced 0 adrenal gland: 139.0;kidney: 105.0 liver: 55.2 -PSMB6 DELTA, Y ENSG00000142507 Proteasome subunit beta 6 17 4796144-4798503 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023312, HPA063656 Supported Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 196.1 -GPR32 RVDR1 ENSG00000142511 G protein-coupled receptor 32 19 50770464-50771732 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030330 Approved Tissue enriched 98 parathyroid gland: 254.8 placenta: 2.5 -SIGLEC10 MGC126774, PRO940, SIGLEC-10, SLG2 ENSG00000142512 Sialic acid binding Ig-like lectin 10 19 51410021-51417803 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025807, HPA027093 Approved Supported Plasma membrane
Actin filaments
Cytosol Tissue enhanced 0 appendix: 49.9;spleen: 37.9 lymph node: 22.4 -ACPT ENSG00000142513 Acid phosphatase, testicular 19 50790415-50795224 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 1.4;testis: 2.3 parathyroid gland: 0.5 -KLK3 APS, PSA ENSG00000142515 Kallikrein-related peptidase 3 19 50854915-50860764 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000070, HPA000764 Supported Tissue enriched 369 prostate: 12913.7 seminal vesicle: 34.9 -ZNF473 DKFZP434N043, HZFP100, KIAA1141 ENSG00000142528 Zinc finger protein 473 19 50025714-50053414 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004191, HPA073309 Uncertain Supported Nucleoplasm Tissue enriched 6 testis: 76.2 fallopian tube: 13.4 -FAM71E1 ENSG00000142530 Family with sequence similarity 71, member E1 19 50466785-50476753 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048111 Approved Nucleoli fibrillar center Tissue enriched 11 testis: 38.5 cerebral cortex: 3.4 -RPS11 S11 ENSG00000142534 Ribosomal protein S11 19 49496365-49499689 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049719 Uncertain Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 6646.8 -PTH2 TIP39 ENSG00000142538 Parathyroid hormone 2 19 49422414-49423441 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.2 -CTD-2545M3.6 ENSG00000142539 19 50415799-50428409 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA018523 Uncertain Tissue enhanced 0 appendix: 1.3;spleen: 1.8 lymph node: 0.7 -RPL13A L13A, TSTA1 ENSG00000142541 Ribosomal protein L13a 19 49487554-49492308 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038751 Approved Approved Nucleoli
Cytosol Expressed in all ovary: 4608.9 -CTU1 ATPBD3, MGC17332, NCS6 ENSG00000142544 Cytosolic thiouridylase subunit 1 19 51097606-51108370 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053797 Uncertain Mixed spleen: 2.9 -NOSIP CGI-25 ENSG00000142546 Nitric oxide synthase interacting protein 19 49555711-49590262 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043464, HPA062132 Approved Validated Nucleus Expressed in all testis: 97.8 -IGLON5 LOC402665 ENSG00000142549 IgLON family member 5 19 51311848-51330354 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041994 Approved Uncertain Nucleus Group enriched 7 adrenal gland: 2.3;cerebral cortex: 11.1;testis: 9.5 seminal vesicle: 1.1 -RCN3 RLP49 ENSG00000142552 Reticulocalbin 3, EF-hand calcium binding domain 19 49527618-49546962 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043134, HPA050402 Uncertain Approved Endoplasmic reticulum
Vesicles Expressed in all small intestine: 46.0 -ZNF614 FLJ21941 ENSG00000142556 Zinc finger protein 614 19 52012765-52030240 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA021197 Uncertain Approved Nucleoplasm
Vesicles
Cytosol Mixed prostate: 15.5 -SLC2A5 GLUT5 ENSG00000142583 Solute carrier family 2 (facilitated glucose/fructose transporter), member 5 1 9035107-9088478 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005449 Supported Tissue enhanced 0 duodenum: 112.1;small intestine: 94.6;testis: 139.5 bone marrow: 64.6 -RERE ARG, ARP, ATN1L, DNB1, KIAA0458 ENSG00000142599 Arginine-glutamic acid dipeptide (RE) repeats 1 8352397-8817643 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024093 Uncertain Expressed in all endometrium: 93.0 -MMEL1 MMEL2, NEPII, NL1, NL2, SEP ENSG00000142606 Membrane metallo-endopeptidase-like 1 1 2590639-2632990 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA007876, HPA008205, CAB020786 Uncertain Tissue enhanced 0 testis: 5.4 stomach: 2.3 -CFAP74 C1orf222, FLJ45476, KIAA1751 ENSG00000142609 Cilia and flagella associated protein 74 1 1921951-2003837 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA028521, HPA029274 Supported Tissue enhanced 0 fallopian tube: 10.4;testis: 9.0 skin: 4.4 -PRDM16 KIAA1675, MEL1, MGC166915, PFM13 ENSG00000142611 PR domain containing 16 1 3069168-3438621 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA050343, HPA060467 Validated Nucleoplasm Mixed duodenum: 7.8 -CELA2A ELA2A ENSG00000142615 Chymotrypsin-like elastase family, member 2A 1 15456728-15472091 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 370 pancreas: 34325.6 ovary: 92.7 -PADI3 PDI3 ENSG00000142619 Peptidyl arginine deiminase, type III 1 17249098-17284233 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043739 Uncertain Approved Nucleoplasm
Vesicles Group enriched 11 esophagus: 3.8;seminal vesicle: 4.9;urinary bladder: 10.6 epididymis: 0.6 -FHAD1 KIAA1937 ENSG00000142621 Forkhead-associated (FHA) phosphopeptide binding domain 1 1 15247272-15400283 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054284 Approved Group enriched 6 fallopian tube: 24.0;lung: 5.3;testis: 24.6 cervix: 3.1 -PADI1 HPAD10, PAD1, PDI, PDI1 ENSG00000142623 Peptidyl arginine deiminase, type I 1 17205126-17246005 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062294 Approved Approved Nucleoplasm
Cytosol Tissue enriched 7 esophagus: 37.3 skin: 5.4 -EPHA2 ECK ENSG00000142627 EPH receptor A2 1 16124337-16156087 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066055 Uncertain Vesicles Tissue enhanced 0 esophagus: 87.1 gallbladder: 44.7 -ARHGEF19 FLJ33962, WGEF ENSG00000142632 Rho guanine nucleotide exchange factor (GEF) 19 1 16197854-16212609 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA068108 Approved Nuclear bodies Tissue enhanced 0 skin: 20.9 thyroid gland: 11.4 -EFHD2 MGC4342 ENSG00000142634 EF-hand domain family, member D2 1 15409895-15430343 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048961 Supported Approved Cytosol Expressed in all spleen: 113.3 -PEX14 ENSG00000142655 Peroxisomal biogenesis factor 14 1 10472288-10630758 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046104, HPA049231 Supported Supported Nucleoli fibrillar center
Peroxisomes Expressed in all seminal vesicle: 32.3 -PGD ENSG00000142657 Phosphogluconate dehydrogenase 1 10398592-10420144 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031314, HPA031315 Approved Supported Approved Intermediate filaments
Cytosol Expressed in all esophagus: 488.7 -MYOM3 FLJ35961 ENSG00000142661 Myomesin 3 1 24056035-24112175 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA028132, HPA029752 Uncertain Approved Vesicles Group enriched 5 heart muscle: 68.0;kidney: 31.7;skeletal muscle: 86.6 testis: 12.1 -SH3BGRL3 ENSG00000142669 SH3 domain binding glutamate-rich protein like 3 1 26279176-26281522 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030848, HPA076219 Approved Approved Nuclear bodies Expressed in all epididymis: 444.6 -CNKSR1 CNK, CNK1, KSR ENSG00000142675 Connector enhancer of kinase suppressor of Ras 1 1 26177403-26189886 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030847 Uncertain Approved Cytosol Mixed parathyroid gland: 20.3 -RPL11 L11 ENSG00000142676 Ribosomal protein L11 1 23691779-23696425 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002734, HPA074839 Approved Approved Vesicles Expressed in all ovary: 4915.0 -IL22RA1 CRF2-9, IL22R ENSG00000142677 Interleukin 22 receptor, alpha 1 1 24119771-24143121 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042399 Approved Group enriched 5 colon: 11.5;duodenum: 20.8;esophagus: 10.2;pancreas: 26.0;rectum: 11.1;skin: 38.8;small intestine: 32.0 gallbladder: 4.0 -ZNF593 ZT86 ENSG00000142684 Zinc finger protein 593 1 26169871-26172060 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054363, HPA059387 Supported Validated Nucleus
Nucleoli Expressed in all appendix: 4.5 -C1orf216 FLJ38984 ENSG00000142686 Chromosome 1 open reading frame 216 1 35713875-35719472 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028299, HPA031343 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 60.7 smooth muscle: 18.5 -KIAA0319L KIAA1837 ENSG00000142687 KIAA0319-like 1 35433490-35557950 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072692 Approved Nucleoli
Golgi apparatus Expressed in all parathyroid gland: 82.6 -EVA1B C1orf78, FAM176B, FLJ10647 ENSG00000142694 Eva-1 homolog B (C. elegans) 1 36322031-36324154 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041928, HPA043537 Approved Approved Cytosol Mixed placenta: 14.7 -C1orf94 MGC15882 ENSG00000142698 Chromosome 1 open reading frame 94 1 34166883-34219131 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045805 Approved Nucleoplasm
Cytosol Tissue enriched 31 testis: 42.2 cerebral cortex: 1.3 -DMRTA2 ENSG00000142700 DMRT-like family A2 1 50417550-50423500 Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA043098, HPA062958 Uncertain Approved Mitochondria Not detected testis: 0.7 -PLK4 Sak, STK18 ENSG00000142731 Polo-like kinase 4 4 127880861-127899195 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017327, HPA035026 Approved Supported Centrosome
Cytosol Tissue enhanced 0 testis: 40.7 bone marrow: 13.9 -MAP3K6 ASK2, MAPKKK6, MEKK6 ENSG00000142733 Mitogen-activated protein kinase kinase kinase 6 1 27355184-27366892 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051192 Approved Approved Nucleus
Plasma membrane
Actin filaments
Cytosol Tissue enhanced 0 skin: 114.6 esophagus: 41.3 -FCN3 FCNH, HAKA1 ENSG00000142748 Ficolin (collagen/fibrinogen domain containing) 3 1 27369112-27374824 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025945 Approved Group enriched 6 liver: 143.5;lung: 267.2 placenta: 32.8 -GPN2 ATPBD1B, FLJ10349 ENSG00000142751 GPN-loop GTPase 2 1 26876133-26890297 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028059 Uncertain Expressed in all parathyroid gland: 24.1 -SYTL1 exophilin-7, FLJ14996, JFC1, SLP1 ENSG00000142765 Synaptotagmin-like 1 1 27342020-27353937 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037825 Approved Mixed skin: 69.1 -WDTC1 ADP, DCAF9, KIAA1037 ENSG00000142784 WD and tetratricopeptide repeats 1 1 27234516-27308633 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028177, HPA028180, HPA028182 Uncertain Supported Golgi apparatus
Vesicles Expressed in all parathyroid gland: 72.3 -CELA3A ELA3, ELA3A ENSG00000142789 Chymotrypsin-like elastase family, member 3A 1 22001656-22012539 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028086, HPA045650 Supported Approved Cytosol Tissue enriched 351 pancreas: 56974.1 ovary: 162.3 -NBPF3 AE2 ENSG00000142794 Neuroblastoma breakpoint family, member 3 1 21440128-21485005 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042595, HPA043692, HPA044023, HPA046971, HPA058050 Approved Tissue enriched 6 testis: 20.4 breast: 3.5 -HSPG2 perlecan, PRCAN, SJS1 ENSG00000142798 Heparan sulfate proteoglycan 2 1 21822245-21937297 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009820, HPA018892, CAB020718 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all adipose tissue: 135.3 -ITGB3BP CENPR, HSU37139, NRIF3, TAP20 ENSG00000142856 Integrin beta 3 binding protein (beta3-endonexin) 1 63440770-63593721 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028463 Approved Supported Nucleoplasm Mixed testis: 36.1 -SERBP1 CGI-55, CHD3IP, DKFZP564M2423, HABP4L, PAI-RBP1, PAIRBP1 ENSG00000142864 SERPINE1 mRNA binding protein 1 1 67407810-67430415 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020559, CAB026297 Supported Validated Cytosol Expressed in all parathyroid gland: 290.1 -BCL10 c-E10, CARMEN, CIPER, CLAP, mE10 ENSG00000142867 B-cell CLL/lymphoma 10 1 85266248-85277090 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001944, HPA017925 Approved Approved Nucleoplasm Expressed in all gallbladder: 30.5 -CYR61 CCN1, GIG1, IGFBP10 ENSG00000142871 Cysteine-rich, angiogenic inducer, 61 1 85580761-85583962 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029853 Uncertain Mixed cervix: 1090.6 -PRKACB PKACb ENSG00000142875 Protein kinase, cAMP-dependent, catalytic, beta 1 84078062-84238498 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010363, HPA029754, HPA071185 Approved Approved Cytosol Tissue enriched 5 cerebral cortex: 317.2 adrenal gland: 63.4 -PIGK GPI8, hGPI8 ENSG00000142892 Phosphatidylinositol glycan anchor biosynthesis, class K 1 77088990-77219430 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056383, HPA057040 Uncertain Expressed in all parathyroid gland: 28.0 -TINAGL1 ARG1, LCN7, LIECG3, P3ECSL, TINAGRP ENSG00000142910 Tubulointerstitial nephritis antigen-like 1 1 31576485-31587686 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048695 Approved Tissue enhanced 0 placenta: 267.7 adipose tissue: 102.4 -AZIN2 ADC, KIAA1945, ODC-p, ODC1L, ODCp ENSG00000142920 Antizyme inhibitor 2 1 33081104-33120530 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028527 Approved Cytosol Tissue enhanced 0 testis: 29.9 cerebral cortex: 17.0 -RPS8 S8 ENSG00000142937 Ribosomal protein S8 1 44775251-44778779 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029266 Supported Endoplasmic reticulum
Cytosol Expressed in all ovary: 5531.8 -KIF2C CT139, KNSL6, MCAK ENSG00000142945 Kinesin family member 2C 1 44739818-44767767 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006219 Supported Nucleoplasm
Centrosome Tissue enriched 7 testis: 134.4 bone marrow: 20.4 -PTPRF LAR ENSG00000142949 Protein tyrosine phosphatase, receptor type, F 1 43525187-43623666 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012710 Uncertain Approved Golgi apparatus Mixed skin: 128.3 -BEST4 VMD2L2 ENSG00000142959 Bestrophin 4 1 44783585-44787705 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058564 Uncertain Tissue enhanced 0 colon: 26.7;rectum: 21.9 duodenum: 11.6 -MOB3C MOB1E, MOBKL2C ENSG00000142961 MOB kinase activator 3C 1 46607715-46616891 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057744 Uncertain Intermediate filaments
Cytosol Expressed in all adipose tissue: 20.6 -CYP4B1 ENSG00000142973 Cytochrome P450, family 4, subfamily B, polypeptide 1 1 46757838-46819413 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004331 Approved Supported Vesicles Tissue enriched 5 lung: 371.8 fallopian tube: 71.5 -TMEM61 ENSG00000143001 Transmembrane protein 61 1 54980792-54992293 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030614 Uncertain Tissue enhanced 0 parathyroid gland: 11.0;salivary gland: 10.2 seminal vesicle: 8.1 -DMRTB1 ENSG00000143006 DMRT-like family B with proline-rich C-terminal, 1 1 53459399-53467488 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036490, HPA058553 Supported Tissue enriched 68 testis: 69.6 epididymis: 1.0 -LMO4 ENSG00000143013 LIM domain only 4 1 87328468-87348923 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022345, HPA045877, HPA061638 Approved Supported Nucleoplasm
Midbody ring Expressed in all cerebral cortex: 218.1 -SYPL2 Mg29 ENSG00000143028 Synaptophysin-like 2 1 109466628-109482137 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA018032 Approved Nucleoplasm Tissue enriched 8 skeletal muscle: 129.4 parathyroid gland: 17.1 -BARHL2 ENSG00000143032 BarH-like homeobox 2 1 90711539-90717237 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA028176, HPA031326 Uncertain Tissue enriched 37 testis: 3.6 epididymis: 0.0 -MTF2 M96, PCL2, TDRD19A ENSG00000143033 Metal response element binding transcription factor 2 1 93079235-93139081 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069047, HPA069066 Validated Nucleoplasm Mixed testis: 30.6 -SLC44A3 CTL3, MGC45474 ENSG00000143036 Solute carrier family 44, member 3 1 94820342-94895246 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047433 Approved Mixed rectum: 39.1 -IGSF3 EWI-3, MGC117164, V8 ENSG00000143061 Immunoglobulin superfamily, member 3 1 116574399-116667755 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036305, HPA036306 Approved Approved Nucleoplasm
Cytosol Mixed skin: 21.6 -ZNF697 MGC45731 ENSG00000143067 Zinc finger protein 697 1 119619422-119647773 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049933 Uncertain Approved Nucleoplasm Mixed placenta: 10.8 -CTTNBP2NL DKFZp547A023 ENSG00000143079 CTTNBP2 N-terminal like 1 112396181-112463456 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007301 Approved Approved Nucleoli fibrillar center
Cytosol Mixed placenta: 28.7 -STRIP1 FAM40A, FAR11A, FLJ14743, KIAA1761 ENSG00000143093 Striatin interacting protein 1 1 110031577-110074641 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060302, HPA060498 Approved Supported Cytosol Expressed in all parathyroid gland: 34.1 -KCNA10 Kv1.8 ENSG00000143105 Potassium channel, voltage gated shaker related subfamily A, member 10 1 110517251-110518838 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA015061, CAB022564 Uncertain Uncertain Nucleoplasm
Cytosol Tissue enhanced 0 testis: 1.0 spleen: 0.2 -PSMA5 ZETA ENSG00000143106 Proteasome subunit alpha 5 1 109399031-109426427 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028392, HPA028398, HPA028441 Approved Mixed cerebral cortex: 14.9 -FNDC7 FLJ35838 ENSG00000143107 Fibronectin type III domain containing 7 1 108712657-108742740 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA028079, HPA054297 Approved Approved Nucleoplasm
Actin filaments Tissue enriched 12 testis: 2.0 bone marrow: 0.1 -C1orf162 MGC24133 ENSG00000143110 Chromosome 1 open reading frame 162 1 111473792-111478512 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026988 Approved Expressed in all spleen: 131.2 -CD53 MOX44, TSPAN25 ENSG00000143119 CD53 molecule 1 110873154-110899928 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047216 Approved Expressed in all lymph node: 468.7 -PROK1 EGVEGF, PK1, PRK1 ENSG00000143125 Prokineticin 1 1 110451200-110457354 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 10 ovary: 237.9;placenta: 75.1;testis: 119.3 seminal vesicle: 15.0 -CELSR2 ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3 ENSG00000143126 Cadherin, EGF LAG seven-pass G-type receptor 2 1 109250019-109275750 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013952 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 45.2 skin: 31.1 -ITGA10 ENSG00000143127 Integrin, alpha 10 1 145891208-145910189 Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA064008 Approved Endoplasmic reticulum Mixed cervix: 8.1 -GPR161 RE2 ENSG00000143147 G protein-coupled receptor 161 1 168079543-168137667 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015576, HPA072047 Uncertain Approved Nucleus
Nucleoli Tissue enhanced 0 smooth muscle: 39.8 endometrium: 28.5 -ALDH9A1 ALDH4, ALDH7, ALDH9, E3 ENSG00000143149 Aldehyde dehydrogenase 9 family, member A1 1 165662216-165698863 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006077, HPA010873 Approved Approved Cytosol Expressed in all thyroid gland: 205.3 -ATP1B1 ATP1B ENSG00000143153 ATPase, Na+/K+ transporting, beta 1 polypeptide 1 169105697-169132722 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012911 Supported Expressed in all kidney: 1327.1 -TIPRL dJ69E11.3, MGC3794, TIP41 ENSG00000143155 TOR signaling pathway regulator 1 168178933-168202114 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027995, HPA054282 Approved Supported Vesicles
Cytosol Expressed in all endometrium: 38.5 -NME7 CFAP67, FLJ37194, NM23-H7 ENSG00000143156 NME/NM23 family member 7 1 169132531-169367967 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038014, HPA054289 Uncertain Approved Mitochondria Expressed in all fallopian tube: 38.6 -POGK BASS2, KIAA15131, KRBOX2, LST003 ENSG00000143157 Pogo transposable element with KRAB domain 1 166839447-166856344 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007838, HPA031630 Approved Supported Nucleoplasm
Vesicles Expressed in all parathyroid gland: 41.5 -MPC2 BRP44, DKFZP564B167 ENSG00000143158 Mitochondrial pyruvate carrier 2 1 167916729-167937040 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056091 Uncertain Expressed in all testis: 353.7 -CREG1 CREG ENSG00000143162 Cellular repressor of E1A-stimulated genes 1 1 167529677-167553767 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056390 Approved Vesicles
Microtubules Expressed in all thyroid gland: 208.5 -DCAF6 IQWD1, PC326 ENSG00000143164 DDB1 and CUL4 associated factor 6 1 167935783-168075843 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054305 Supported Nucleus
Focal adhesion sites Expressed in all skeletal muscle: 223.5 -GPA33 A33 ENSG00000143167 Glycoprotein A33 (transmembrane) 1 167052836-167166479 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018858, CAB025943 Supported Group enriched 8 colon: 186.8;duodenum: 134.3;rectum: 191.4;small intestine: 133.9 appendix: 19.9 -RXRG NR2B3 ENSG00000143171 Retinoid X receptor, gamma 1 165400917-165445355 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level CAB002615 Uncertain Tissue enhanced 0 skeletal muscle: 16.7 cervix: 4.6 -TBX19 dj747L4.1, TPIT ENSG00000143178 T-box 19 1 168281040-168314426 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA005800 Supported Approved Nuclear speckles Mixed endometrium: 5.3 -UCK2 UMPK ENSG00000143179 Uridine-cytidine kinase 2 1 165827531-165911618 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057128 Approved Nucleus Expressed in all placenta: 41.0 -TMCO1 HP10122, TMCC4 ENSG00000143183 Transmembrane and coiled-coil domains 1 1 165724293-165827755 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054768 Supported Endoplasmic reticulum Expressed in all thyroid gland: 157.3 -XCL1 ATAC, LPTN, LTN, lymphotactin, SCM-1, SCM-1a, SCYC1 ENSG00000143184 Chemokine (C motif) ligand 1 1 168576473-168582077 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA057725 Approved Tissue enhanced 0 spleen: 5.8 endometrium: 3.3 -XCL2 SCM-1b, SCYC2 ENSG00000143185 Chemokine (C motif) ligand 2 1 168540765-168543997 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA057725 Approved Tissue enhanced 0 spleen: 14.3 bone marrow: 8.4 -POU2F1 OCT1, OTF1 ENSG00000143190 POU class 2 homeobox 1 1 167220829-167427345 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002608, HPA058559, HPA064323 Supported Supported Nucleoplasm
Endoplasmic reticulum
Vesicles Mixed parathyroid gland: 7.9 -MAEL CT128, FLJ14904, SPATA35 ENSG00000143194 Maelstrom spermatogenic transposon silencer 1 166975582-167022214 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 30 testis: 281.0 placenta: 9.2 -ILDR2 C1orf32 ENSG00000143195 Immunoglobulin-like domain containing receptor 2 1 166895711-166975482 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA012545 Uncertain Tissue enhanced 0 cerebral cortex: 11.4;testis: 17.4 kidney: 3.0 -DPT ENSG00000143196 Dermatopontin 1 168695459-168729264 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065548 Approved Vesicles Mixed adipose tissue: 330.1 -MGST3 GST-III ENSG00000143198 Microsomal glutathione S-transferase 3 1 165630861-165661796 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053311 Approved Nucleus Expressed in all epididymis: 621.5 -ADCY10 HCA2, RP1-313L4.2, SAC, SACI, Sacy ENSG00000143199 Adenylate cyclase 10 (soluble) 1 167809388-167914215 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015243, HPA017749 Approved Tissue enriched 11 testis: 32.9 liver: 3.1 -RFWD2 COP1, FLJ10416, RNF200 ENSG00000143207 Ring finger and WD repeat domain 2, E3 ubiquitin protein ligase 1 175944831-176207493 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 41.9 -PVRL4 LNIR, nectin-4, PRR4 ENSG00000143217 Poliovirus receptor-related 4 1 161070995-161089599 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010775 Supported Supported Plasma membrane Tissue enhanced 0 esophagus: 46.1;skin: 79.8 placenta: 17.1 -UFC1 HSPC155 ENSG00000143222 Ubiquitin-fold modifier conjugating enzyme 1 1 161152776-161158856 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027481, HPA028722 Approved Approved Nuclear speckles
Cytosol Expressed in all fallopian tube: 250.5 -PPOX PPO, VP ENSG00000143224 Protoporphyrinogen oxidase 1 161166410-161178013 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030123 Uncertain Approved Mitochondria
Cytosol Expressed in all fallopian tube: 37.3 -FCGR2A CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2 ENSG00000143226 Fc fragment of IgG, low affinity IIa, receptor (CD32) 1 161505430-161524013 CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010718, HPA014730 Supported Tissue enhanced 0 appendix: 151.6;placenta: 159.2 lung: 118.4 -NUF2 CDCA1, CT106, NUF2R ENSG00000143228 NUF2, NDC80 kinetochore complex component 1 163266576-163355764 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059692 Supported Nucleus Tissue enhanced 0 testis: 94.5 lymph node: 22.0 -RGS5 ENSG00000143248 Regulator of G-protein signaling 5 1 163111121-163321791 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA001821 Approved Supported Cytosol Mixed adrenal gland: 408.1 -SDHC CYB560, PGL3 ENSG00000143252 Succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1 161314257-161375340 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all kidney: 187.3 -PFDN2 ENSG00000143256 Prefoldin subunit 2 1 161100556-161118111 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028700, HPA058304 Approved Validated Cytosol Expressed in all cerebral cortex: 109.9 -NR1I3 CAR, CAR1, MB67 ENSG00000143257 Nuclear receptor subfamily 1, group I, member 3 1 161229666-161238302 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA051365 Approved Nucleoplasm Tissue enriched 9 liver: 82.0 kidney: 9.6 -USP21 USP16, USP23 ENSG00000143258 Ubiquitin specific peptidase 21 1 161159450-161165723 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028397 Uncertain Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all fallopian tube: 45.2 -F13B FXIIIB ENSG00000143278 Coagulation factor XIII, B polypeptide 1 197039191-197067267 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003827, HPA052139 Supported Tissue enriched 108 liver: 122.1 duodenum: 1.1 -PRCC RCCP1 ENSG00000143294 Papillary renal cell carcinoma (translocation-associated) 1 156750610-156800817 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017151, HPA019463, HPA019481 Supported Validated Nuclear speckles Expressed in all cerebral cortex: 54.7 -FCRL5 BXMAS1, CD307e, FCRH5, IRTA2 ENSG00000143297 Fc receptor-like 5 1 157513377-157552520 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lymph node: 29.1;spleen: 20.8;tonsil: 33.8 appendix: 18.5 -RRNAD1 C1orf66, CGI-41 ENSG00000143303 Ribosomal RNA adenine dimethylase domain containing 1 1 156728442-156736960 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047426 Approved Approved Nucleoli
Cytosol Expressed in all thyroid gland: 49.0 -MRPL24 MRP-L18 ENSG00000143314 Mitochondrial ribosomal protein L24 1 156737303-156741590 Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030295 Approved Expressed in all fallopian tube: 116.2 -PIGM GPI-MT-I ENSG00000143315 Phosphatidylinositol glycan anchor biosynthesis, class M 1 160027673-160031991 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047418 Uncertain Mixed parathyroid gland: 16.1 -CASQ1 CASQ, PDIB1 ENSG00000143318 Calsequestrin 1 (fast-twitch, skeletal muscle) 1 160190556-160201886 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007845, CAB015170, HPA026823 Supported Uncertain Nucleoplasm
Mitochondria Tissue enriched 33 skeletal muscle: 1514.4 esophagus: 45.5 -ISG20L2 FLJ12671 ENSG00000143319 Interferon stimulated exonuclease gene 20kDa-like 2 1 156721891-156728799 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028005, HPA054285 Approved Supported Nucleoplasm Expressed in all testis: 85.7 -CRABP2 CRABP-II ENSG00000143320 Cellular retinoic acid binding protein 2 1 156699606-156705816 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004135 Supported Supported Nucleoplasm
Cytosol Tissue enriched 5 esophagus: 1046.8 skin: 193.7 -HDGF HMG1L2 ENSG00000143321 Hepatoma-derived growth factor 1 156742107-156766925 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026035, HPA048728, HPA053422 Supported Validated Nucleoplasm Expressed in all bone marrow: 190.7 -ABL2 ABLL, ARG ENSG00000143322 ABL proto-oncogene 2, non-receptor tyrosine kinase 1 179099327-179229684 Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001866, CAB017106 Uncertain Supported Nucleoplasm Mixed gallbladder: 20.3 -XPR1 SYG1, X3 ENSG00000143324 Xenotropic and polytropic retrovirus receptor 1 1 180632004-180890251 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016557 Supported Approved Endoplasmic reticulum
Golgi apparatus Expressed in all testis: 31.1 -RGS16 A28-RGS14, RGS-r ENSG00000143333 Regulator of G-protein signaling 16 1 182598623-182604408 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053250, HPA055824 Uncertain Approved Cytosol Tissue enriched 7 thyroid gland: 170.9 gallbladder: 25.2 -TOR1AIP1 FLJ13142, LAP1B ENSG00000143337 Torsin A interacting protein 1 1 179882042-179925000 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047151, HPA050546 Supported Validated Nuclear membrane Expressed in all thyroid gland: 78.9 -FAM163A C1orf76, MGC16664 ENSG00000143340 Family with sequence similarity 163, member A 1 179743163-179816198 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA010778 Uncertain Tissue enhanced 0 adrenal gland: 7.7;testis: 9.7 gallbladder: 1.8 -HMCN1 ARMD1, FBLN6, FIBL-6, FIBL6 ENSG00000143341 Hemicentin 1 1 185734551-186190949 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051677 Uncertain Tissue enhanced 0 lung: 22.3 prostate: 11.9 -RGL1 RGL ENSG00000143344 Ral guanine nucleotide dissociation stimulator-like 1 1 183636085-183928531 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019788 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Mixed spleen: 63.5 -LYPLAL1 Q96AV0 ENSG00000143353 Lysophospholipase-like 1 1 219173844-219212865 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045806 Approved Supported Cytosol Mixed kidney: 42.6 -LHX9 ENSG00000143355 LIM homeobox 9 1 197911902-197935478 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA009695 Uncertain Approved Nucleus Tissue enhanced 0 ovary: 11.4;testis: 4.5 lung: 2.2 -PRUNE DRES-17, HTCD37 ENSG00000143363 Prune exopolyphosphatase 1 151008420-151035713 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028411 Uncertain Supported Cytosol Expressed in all thyroid gland: 53.7 -RORC NR1F3, RORG, RZRG, TOR ENSG00000143365 RAR-related orphan receptor C 1 151806071-151831872 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA065620 Supported Nuclear bodies Mixed thyroid gland: 51.8 -TUFT1 ENSG00000143367 Tuftelin 1 1 151540305-151583583 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028112, HPA054301 Approved Approved Vesicles Tissue enhanced 0 skin: 93.1 esophagus: 25.9 -SF3B4 Hsh49, SAP49, SF3b49 ENSG00000143368 Splicing factor 3b, subunit 4, 49kDa 1 149923317-149928344 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028578, HPA064660 Approved Approved Nuclear speckles Expressed in all testis: 71.6 -ECM1 ENSG00000143369 Extracellular matrix protein 1 1 150508062-150513789 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027241 Approved Approved Nucleoplasm
Cytosol Group enriched 6 epididymis: 572.2;esophagus: 993.1 tonsil: 127.6 -ZNF687 KIAA1441 ENSG00000143373 Zinc finger protein 687 1 151281618-151292180 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021193, HPA023948 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 25.9 -TARS2 FLJ12528, TARSL1 ENSG00000143374 Threonyl-tRNA synthetase 2, mitochondrial (putative) 1 150487364-150507609 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028626 Approved Approved Nucleoplasm
Intermediate filaments
Cytosol Expressed in all parathyroid gland: 28.8 -CGN KIAA1319 ENSG00000143375 Cingulin 1 151510510-151538692 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017193, HPA027586, HPA027587, HPA027657 Supported Supported Plasma membrane
Cell Junctions Tissue enhanced 0 parathyroid gland: 73.3 small intestine: 63.2 -SNX27 KIAA0488, MGC20471, MY014 ENSG00000143376 Sorting nexin family member 27 1 151612065-151699091 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045816 Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 18.8 -SETDB1 ESET, KG1T, KIAA0067, KMT1E, TDRD21 ENSG00000143379 SET domain, bifurcated 1 1 150926263-150964744 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018142, HPA058484 Uncertain Validated Nucleoplasm
Cytosol Expressed in all testis: 46.1 -ADAMTSL4 DKFZP434K1772, TSRC1 ENSG00000143382 ADAMTS-like 4 1 150549369-150560937 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006279 Approved Approved Plasma membrane
Cytosol Tissue enhanced 0 placenta: 89.1 lung: 32.7 -MCL1 BCL2L3, Mcl-1 ENSG00000143384 Myeloid cell leukemia 1 1 150574551-150579738 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002781, HPA008455, HPA031125, CAB068195 Approved Validated Mitochondria Expressed in all gallbladder: 662.8 -CTSK CTSO, CTSO2, PKND, PYCD ENSG00000143387 Cathepsin K 1 150796208-150808323 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050346 Supported Vesicles Expressed in all cervix: 571.4 -RFX5 ENSG00000143390 Regulatory factor X, 5 (influences HLA class II expression) 1 151340640-151347357 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018519 Supported Expressed in all lymph node: 86.8 -PI4KB PI4K-BETA, pi4K92, PIK4CB ENSG00000143393 Phosphatidylinositol 4-kinase, catalytic, beta 1 151291797-151327715 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006280, HPA006281, CAB022071 Approved Supported Golgi apparatus Expressed in all parathyroid gland: 101.2 -PIP5K1A ENSG00000143398 Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 1 151197949-151249536 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029366 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 69.4 -ANP32E LANP-L, LANPL, MGC5350 ENSG00000143401 Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 1 150218417-150236156 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021114, HPA063133, HPA067561 Supported Approved Nucleoplasm
Centrosome
Cytosol Expressed in all lymph node: 85.2 -FAM63A FLJ11280 ENSG00000143409 Family with sequence similarity 63, member A 1 150996086-151008375 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028351, HPA028358, HPA061086 Approved Supported Nucleoplasm Expressed in all thyroid gland: 79.6 -ANXA9 ANX31 ENSG00000143412 Annexin A9 1 150982017-150995634 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028404, HPA028698 Supported Approved Nuclear speckles
Cytosol Expressed in all parathyroid gland: 46.5 -SELENBP1 hSBP, hSP56, LPSB ENSG00000143416 Selenium binding protein 1 1 151364302-151372733 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005741, CAB008366, HPA011731 Supported Supported Nucleoli Expressed in all rectum: 496.0 -CERS2 FLJ10243, LASS2, SP260 ENSG00000143418 Ceramide synthase 2 1 150960583-150975004 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027262 Approved Supported Nuclear membrane
Endoplasmic reticulum Expressed in all liver: 408.6 -ENSA ARPP-19e, MGC4319, MGC78563, MGC8394 ENSG00000143420 Endosulfine alpha 1 150600851-150629612 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051294 Uncertain Approved Nucleus
Nucleoli
Microtubules
Cytosol Expressed in all esophagus: 268.4 -SEMA6C KIAA1869 ENSG00000143434 Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 1 151131685-151146664 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA071220 Approved Endoplasmic reticulum Tissue enhanced 0 skeletal muscle: 111.3 testis: 33.9 -MRPL9 ENSG00000143436 Mitochondrial ribosomal protein L9 1 151759643-151763564 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008579 Approved Supported Mitochondria Expressed in all parathyroid gland: 58.4 -ARNT bHLHe2, HIF-1beta ENSG00000143437 Aryl hydrocarbon receptor nuclear translocator 1 150809705-150876768 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001759, CAB004318 Supported Supported Nucleus
Nuclear bodies Expressed in all ovary: 46.6 -POGZ KIAA0461, ZNF280E, ZNF635m ENSG00000143442 Pogo transposable element with ZNF domain 1 151402724-151459465 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006800, HPA008781 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 74.9 -C1orf56 FLJ20519, MENT ENSG00000143443 Chromosome 1 open reading frame 56 1 151047740-151051986 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037429, HPA037430 Supported Tissue enhanced 0 testis: 48.6 parathyroid gland: 12.7 -OAZ3 ENSG00000143450 Ornithine decarboxylase antizyme 3 1 151762899-151771334 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA030136 Supported Nucleoplasm Tissue enriched 9 testis: 195.3 parathyroid gland: 20.6 -HORMAD1 CT46, DKFZP434A1315 ENSG00000143452 HORMA domain containing 1 1 150698060-150720888 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028346, HPA037850 Supported Approved Nucleoplasm Tissue enriched 25 testis: 223.6 skin: 8.8 -GOLPH3L GPP34R ENSG00000143457 Golgi phosphoprotein 3-like 1 150646225-150697144 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028558 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all thyroid gland: 51.2 -GABPB2 MGC29891 ENSG00000143458 GA binding protein transcription factor, beta subunit 2 1 151070578-151125542 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028471, HPA058483 Uncertain Supported Nucleoplasm
Cytosol Mixed testis: 20.1 -SYT14 FLJ34198, sytXIV ENSG00000143469 Synaptotagmin XIV 1 209938174-210171315 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA036963 Supported Vesicles Tissue enhanced 0 testis: 6.1;thyroid gland: 8.7 cerebral cortex: 2.5 -KCNH1 eag, eag1, h-eag, Kv10.1 ENSG00000143473 Potassium channel, voltage gated eag related subfamily H, member 1 1 210678315-211134115 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014551, HPA019445 Supported Approved Vesicles Tissue enriched 12 cerebral cortex: 11.5 testis: 0.9 -DTL CDT2, DCAF2, L2DTL, RAMP ENSG00000143476 Denticleless E3 ubiquitin protein ligase homolog (Drosophila) 1 212035553-212107400 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028016, HPA032023, HPA032031 Uncertain Validated Nucleus
Cytosol Tissue enhanced 0 testis: 23.7 bone marrow: 8.2 -DYRK3 hYAK3-2, RED, REDK ENSG00000143479 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 1 206635536-206684419 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA075041 Supported Nucleoplasm
Cytosol Tissue enhanced 0 testis: 86.3 gallbladder: 23.2 -EIF2D LGTN ENSG00000143486 Eukaryotic translation initiation factor 2D 1 206571292-206612463 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028220 Approved Approved Nuclear bodies
Cytosol Expressed in all ovary: 73.9 -INTS7 C1orf73, DKFZP434B168, INT7 ENSG00000143493 Integrator complex subunit 7 1 211940399-212035542 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048769 Supported Nucleus
Nuclear speckles Tissue enhanced 0 testis: 38.6 thyroid gland: 11.1 -VASH2 FLJ12505 ENSG00000143494 Vasohibin 2 1 212950520-212992037 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045820 Approved Cytosol Tissue enhanced 0 testis: 11.3 appendix: 4.7 -TAF1A SL1, TAFI48 ENSG00000143498 TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 1 222557902-222589933 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053101, HPA054334 Approved Validated Nucleus
Vesicles
Microtubules Mixed testis: 12.0 -SMYD2 HSKM-B, KMT3C, ZMYND14 ENSG00000143499 SET and MYND domain containing 2 1 214281102-214337131 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029023 Uncertain Approved Intermediate filaments
Mitochondria
Cytosol Expressed in all heart muscle: 126.2 -SUSD4 FLJ10052 ENSG00000143502 Sushi domain containing 4 1 223220819-223364202 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058296 Uncertain Approved Vesicles Tissue enhanced 0 esophagus: 42.6 cerebral cortex: 38.6 -DUSP10 MKP-5, MKP5 ENSG00000143507 Dual specificity phosphatase 10 1 221701424-221742176 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA016758 Approved Supported Nucleoplasm
Golgi apparatus
Cytosol Mixed liver: 16.8 -HHIPL2 FLJ13840, KIAA1822L ENSG00000143512 HHIP-like 2 1 222522258-222548103 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059673 Approved Uncertain Mitochondria
Cytosol Tissue enhanced 0 testis: 9.1;thyroid gland: 3.4 prostate: 1.3 -TP53BP2 53BP2, ASPP2, PPP1R13A ENSG00000143514 Tumor protein p53 binding protein 2 1 223779899-223845972 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021603, HPA050429 Supported Validated Cell Junctions
Cytosol Expressed in all thyroid gland: 34.4 -ATP8B2 ATPID, KIAA1137 ENSG00000143515 ATPase, aminophospholipid transporter, class I, type 8B, member 2 1 154325553-154351307 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046680 Approved Approved Golgi apparatus
Vesicles
Cytosol Mixed smooth muscle: 60.2 -FLG2 IFPS ENSG00000143520 Filaggrin family member 2 1 152348735-152360006 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028699 Approved Tissue enriched 14 skin: 580.4 breast: 42.4 -CRNN C1orf10, SEP53 ENSG00000143536 Cornulin 1 152409243-152414263 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024343, CAB026182 Supported Tissue enriched 19 esophagus: 4534.5 tonsil: 235.8 -ADAM15 MDC15 ENSG00000143537 ADAM metallopeptidase domain 15 1 155050566-155062775 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011633, HPA072878 Uncertain Uncertain Vesicles Expressed in all skin: 72.8 -JTB hJT ENSG00000143543 Jumping translocation breakpoint 1 153974269-153977688 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006514 Approved Approved Vesicles
Actin filaments Expressed in all epididymis: 114.3 -RAB13 ENSG00000143545 RAB13, member RAS oncogene family 1 153981617-153986358 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003996 Approved Supported Plasma membrane
Cytosol Expressed in all prostate: 153.9 -S100A8 60B8AG, CAGA, CFAG, CGLA, MRP8, P8 ENSG00000143546 S100 calcium binding protein A8 1 153390032-153391188 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002791, HPA024372 Supported Supported Intermediate filaments Group enriched 9 bone marrow: 14952.4;esophagus: 12812.0;tonsil: 5078.4 appendix: 1261.4 -TPM3 NEM1, TRK ENSG00000143549 Tropomyosin 3 1 154155304-154194648 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000261, HPA009066, HPA047089, HPA053624 Approved Approved Actin filaments
Cytosol Tissue enriched 7 skeletal muscle: 2869.9 bone marrow: 429.2 -NUP210L ENSG00000143552 Nucleoporin 210kDa-like 1 153992685-154155116 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047195, HPA064245, HPA066707 Supported Approved Nuclear bodies Tissue enriched 93 testis: 47.5 seminal vesicle: 0.5 -SNAPIN BLOC1S7, BORCS3, SNAPAP ENSG00000143553 SNAP-associated protein 1 153658654-153661830 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046974 Approved Approved Nucleoli
Golgi apparatus Expressed in all fallopian tube: 41.8 -SLC27A3 ACSVL3, FATP3, MGC4365 ENSG00000143554 Solute carrier family 27 (fatty acid transporter), member 3 1 153774354-153780157 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA006935, HPA067508 Uncertain Supported Endoplasmic reticulum Tissue enhanced 0 epididymis: 43.7 lung: 20.9 -S100A7 PSOR1, S100A7c ENSG00000143556 S100 calcium binding protein A7 1 153457744-153460701 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001453, HPA006997, CAB033766 Supported Group enriched 6 skin: 325.1;tonsil: 921.8 esophagus: 96.4 -UBAP2L KIAA0144, NICE-4 ENSG00000143569 Ubiquitin associated protein 2-like 1 154220179-154271510 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035068 Approved Approved Nuclear speckles
Cytosol Expressed in all testis: 122.8 -SLC39A1 ZIP1, ZIRTL ENSG00000143570 Solute carrier family 39 (zinc transporter), member 1 1 153959099-153968184 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016506 Uncertain Cytosol Expressed in all placenta: 133.4 -HAX1 HCLSBP1, HS1BP1 ENSG00000143575 HCLS1 associated protein X-1 1 154272511-154275875 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055141, HPA075289 Approved Supported Mitochondria Expressed in all testis: 114.3 -CREB3L4 AIbZIP, ATCE1, CREB3, CREB4, hJAL ENSG00000143578 CAMP responsive element binding protein 3-like 4 1 153967534-153974363 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038122 Supported Approved Nucleoplasm
Nuclear membrane
Mitochondria Expressed in all prostate: 171.5 -EFNA3 Ehk1-L, EPLG3, LERK3 ENSG00000143590 Ephrin-A3 1 155078872-155087538 Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB010494 Uncertain Tissue enhanced 0 skin: 51.5 cerebral cortex: 17.1 -AQP10 ENSG00000143595 Aquaporin 10 1 154321090-154325325 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA065947 Supported Group enriched 8 duodenum: 70.3;small intestine: 50.1 fallopian tube: 7.1 -KCNN3 hSK3, KCa2.3, SKCA3 ENSG00000143603 Potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 1 154697455-154870280 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA017990, HPA057127 Uncertain Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 25.4 fallopian tube: 9.4 -C1orf43 DKFZp586G1722, NICE-3 ENSG00000143612 Chromosome 1 open reading frame 43 1 154206706-154220628 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA010725 Approved Expressed in all kidney: 194.2 -GATAD2B P66beta ENSG00000143614 GATA zinc finger domain containing 2B 1 153804725-153922975 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017015 Approved Validated Nucleoplasm Expressed in all testis: 16.0 -ILF2 NF45 ENSG00000143621 Interleukin enhancer binding factor 2 1 153661788-153671048 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007484 Supported Validated Nucleus
Nucleoli Expressed in all testis: 210.7 -RIT1 MGC125864, MGC125865, RIBB, RIT, ROC1 ENSG00000143622 Ras-like without CAAX 1 1 155897808-155911404 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053249 Approved Expressed in all bone marrow: 50.6 -INTS3 C1orf60, FLJ21919, INT3, SOSS-A ENSG00000143624 Integrator complex subunit 3 1 153728067-153774808 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA074391 Supported Nucleus
Nucleoli Expressed in all fallopian tube: 16.4 -PKLR ENSG00000143627 Pyruvate kinase, liver and RBC 1 155289839-155301434 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006653, CAB034376, CAB034378 Supported Approved Cytosol Tissue enhanced 0 kidney: 14.0;liver: 26.4 bone marrow: 7.8 -HCN3 KIAA1535 ENSG00000143630 Hyperpolarization activated cyclic nucleotide gated potassium channel 3 1 155277583-155289848 Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026584 Approved Mixed skin: 3.0 -FLG ENSG00000143631 Filaggrin 1 152302175-152325203 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002210, HPA027505, HPA030188, HPA030189 Supported Supported Vesicles Tissue enriched 26 skin: 549.7 breast: 21.0 -ACTA1 ACTA, NEM3 ENSG00000143632 Actin, alpha 1, skeletal muscle 1 229431245-229434098 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000045, HPA041264, HPA041271 Supported Tissue enriched 18 skeletal muscle: 45988.0 heart muscle: 2575.1 -C1orf131 DKFZp547B1713 ENSG00000143633 Chromosome 1 open reading frame 131 1 231223763-231241187 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028452, HPA029920 Approved Validated Nucleus
Nucleoli
Cytosol Expressed in all duodenum: 22.2 -GALNT2 GalNAc-T2 ENSG00000143641 Polypeptide N-acetylgalactosaminyltransferase 2 1 230057990-230282124 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011222 Supported Validated Golgi apparatus Expressed in all ovary: 48.5 -TTC13 FLJ22584 ENSG00000143643 Tetratricopeptide repeat domain 13 1 230906243-230978875 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA018022, HPA051558 Uncertain Approved Nucleoplasm Expressed in all lymph node: 23.3 -SCCPDH CGI-49, NET11 ENSG00000143653 Saccharopine dehydrogenase (putative) 1 246724047-246768137 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050775 Uncertain Approved Vesicles Expressed in all testis: 240.1 -LYST CHS, CHS1 ENSG00000143669 Lysosomal trafficking regulator 1 235661041-235883640 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053366, HPA055725 Supported Nucleoplasm Mixed bone marrow: 20.9 -RP5-862P8.2 ENSG00000143674 Mitogen-activated protein kinase kinase kinase MLK4 1 233327768-233385148 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007636 Uncertain Approved Plasma membrane
Cytosol Mixed testis: 17.7 -CEP170 FAM68A, KAB, KIAA0470 ENSG00000143702 Centrosomal protein 170kDa 1 243124428-243255348 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042151, HPA045787 Uncertain Validated Centrosome
Cytosol Tissue enhanced 0 testis: 106.3 cerebral cortex: 44.9 -ACP1 HAAP, LMW-PTP ENSG00000143727 Acid phosphatase 1, soluble 2 264140-278283 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016754 Approved Approved Nucleus
Cytosol Expressed in all adrenal gland: 129.4 -SNAP47 C1orf142, SNAP-47, SVAP1 ENSG00000143740 Synaptosomal-associated protein, 47kDa 1 227728539-227781231 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028167 Supported Approved Cytosol Expressed in all testis: 56.5 -SRP9 ENSG00000143742 Signal recognition particle 9kDa 1 225777813-225790466 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 341.1 -NVL ENSG00000143748 Nuclear VCP-like 1 224227334-224330387 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028207, HPA028219, HPA028224, HPA028654 Supported Validated Nucleoli Expressed in all skin: 18.7 -SDE2 C1orf55, FLJ35382 ENSG00000143751 SDE2 telomere maintenance homolog (S. pombe) 1 225982702-225999331 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028467, HPA031255, HPA031256 Approved Approved Nuclear speckles
Golgi apparatus
Plasma membrane
Cytosol Expressed in all thyroid gland: 21.0 -DEGS1 DEGS-1, Des-1, DES1, FADS7, MLD ENSG00000143753 Delta(4)-desaturase, sphingolipid 1 1 224175756-224193441 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA076422 Supported Mitochondria Expressed in all skin: 617.7 -FBXO28 CENP-30, Fbx28, FLJ10766, KIAA0483 ENSG00000143756 F-box protein 28 1 224114087-224162047 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003289 Approved Nucleoplasm
Focal adhesion sites Expressed in all skin: 25.0 -ARF1 ENSG00000143761 ADP-ribosylation factor 1 1 228082660-228099212 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007742 Uncertain Approved Plasma membrane
Cytosol Expressed in all placenta: 381.7 -LEFTY2 EBAF, LEFTA, LEFTYA, TGFB4 ENSG00000143768 Left-right determination factor 2 1 225936598-225941489 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB025801, HPA047883, HPA056210 Approved Group enriched 6 endometrium: 270.5;smooth muscle: 56.3 ovary: 26.0 -CNIH4 HSPC163 ENSG00000143771 Cornichon family AMPA receptor auxiliary protein 4 1 224356850-224379459 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044268 Approved Expressed in all smooth muscle: 27.1 -ITPKB IP3-3KB, IP3KB ENSG00000143772 Inositol-trisphosphate 3-kinase B 1 226631690-226739323 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030273, HPA072923 Uncertain Approved Nucleus Expressed in all cerebral cortex: 61.8 -GUK1 ENSG00000143774 Guanylate kinase 1 1 228139962-228148984 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028118, HPA048587 Approved Uncertain Nucleoplasm
Cytosol Expressed in all cerebral cortex: 265.5 -CDC42BPA FLJ23347, KIAA0451, MRCK, MRCKA, PK428 ENSG00000143776 CDC42 binding protein kinase alpha (DMPK-like) 1 226989865-227318474 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071252 Approved Intermediate filaments Expressed in all testis: 45.0 -CNIH3 CNIH-3, FLJ38993 ENSG00000143786 Cornichon family AMPA receptor auxiliary protein 3 1 224434660-224740549 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 14.8 testis: 4.2 -C1orf35 MGC4174, MMTAG2 ENSG00000143793 Chromosome 1 open reading frame 35 1 228100726-228105411 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046175 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Expressed in all skin: 14.3 -MBOAT2 FLJ14415, FLJ90298, OACT2 ENSG00000143797 Membrane bound O-acyltransferase domain containing 2 2 8852690-9003813 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014836 Uncertain Approved Vesicles Tissue enhanced 0 parathyroid gland: 49.4 cerebral cortex: 29.8 -PARP1 ADPRT, PARP, PPOL ENSG00000143799 Poly (ADP-ribose) polymerase 1 1 226360691-226408079 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727 Supported Validated Nucleus Expressed in all parathyroid gland: 195.1 -PSEN2 AD3L, AD4, PS2, STM2 ENSG00000143801 Presenilin 2 1 226870184-226896105 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013634, HPA038005 Supported Nucleus Expressed in all parathyroid gland: 29.1 -PYCR2 P5CR2 ENSG00000143811 Pyrroline-5-carboxylate reductase family, member 2 1 225919877-225924340 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056873 Approved Approved Mitochondria Expressed in all fallopian tube: 71.0 -LBR DHCR14B, TDRD18 ENSG00000143815 Lamin B receptor 1 225401502-225428925 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049840, HPA062236 Supported Validated Nuclear membrane Expressed in all lymph node: 99.8 -WNT9A WNT14 ENSG00000143816 Wingless-type MMTV integration site family, member 9A 1 227918656-227947898 Plasma proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed endometrium: 7.1 -EPHX1 EPHX ENSG00000143819 Epoxide hydrolase 1, microsomal (xenobiotic) 1 225810092-225845563 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020593, HPA048847 Supported Expressed in all adrenal gland: 1091.2 -REN ENSG00000143839 Renin 1 204154819-204166322 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005131, CAB025903 Approved Tissue enhanced 0 kidney: 50.8;placenta: 21.0 endometrium: 8.9 -SOX13 ICA12, MGC117216, Sox-13 ENSG00000143842 SRY (sex determining region Y)-box 13 1 204073115-204127743 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051790, HPA054843 Validated Nucleoplasm Mixed parathyroid gland: 52.4 -ETNK2 EKI2, FLJ10761 ENSG00000143845 Ethanolamine kinase 2 1 204131062-204152003 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA057167 Supported Tissue enhanced 0 kidney: 109.8;liver: 119.6;testis: 142.1 ovary: 43.3 -PPFIA4 ENSG00000143847 Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 1 203026498-203078740 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA053419, HPA054132 Supported Tissue enhanced 0 cerebral cortex: 24.8;heart muscle: 13.3 skeletal muscle: 6.5 -PLEKHA6 KIAA0969, PEPP3 ENSG00000143850 Pleckstrin homology domain containing, family A member 6 1 204218851-204377665 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028152, HPA054311 Approved Supported Vesicles
Cell Junctions
Microtubule organizing center Mixed stomach: 26.7 -PTPN7 HEPTP, LC-PTP ENSG00000143851 Protein tyrosine phosphatase, non-receptor type 7 1 202147013-202161588 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009530, HPA019118 Approved Tissue enhanced 0 bone marrow: 25.2;lymph node: 24.6 tonsil: 20.1 -SYT2 ENSG00000143858 Synaptotagmin II 1 202590596-202710417 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030372, HPA063655 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 2.1 adrenal gland: 1.8 -ARL8A ARL10B, FLJ45195, Gie2 ENSG00000143862 ADP-ribosylation factor-like 8A 1 202133404-202144743 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038759, HPA040515, HPA045924 Approved Expressed in all cerebral cortex: 113.9 -OSR1 ODD ENSG00000143867 Odd-skipped related transciption factor 1 2 19351485-19358653 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015525 Uncertain Mixed adipose tissue: 21.9 -GDF7 BMP12 ENSG00000143869 Growth differentiation factor 7 2 20666664-20679245 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 seminal vesicle: 29.2 endometrium: 11.5 -PDIA6 ERp5, P5, TXNDC7 ENSG00000143870 Protein disulfide isomerase family A, member 6 2 10783391-10837977 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034347, HPA034652, HPA034653 Supported Supported Endoplasmic reticulum
Cytosol Expressed in all thyroid gland: 589.5 -RHOB ARH6, ARHB, MST081, RhoB, RHOH6 ENSG00000143878 Ras homolog family member B 2 20447074-20449445 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all adrenal gland: 714.3 -ATP6V1C2 ATP6C2, VMA5 ENSG00000143882 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 2 10721649-10785110 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034734, HPA034735 Uncertain Uncertain Mitochondria Tissue enhanced 0 cervix, uterine: 81.6;epididymis: 101.2;skin: 124.0 placenta: 54.5 -HNRNPLL HNRPLL ENSG00000143889 Heterogeneous nuclear ribonucleoprotein L-like 2 38561978-38603586 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046084 Approved Approved Nucleus
Mitochondria
Cytosol Expressed in all testis: 37.3 -GALM ENSG00000143891 Galactose mutarotase (aldose 1-epimerase) 2 38665910-38741237 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035472, HPA035473 Supported Approved Nucleoplasm Expressed in all kidney: 117.1 -CAMKMT C2orf34, CLNMT ENSG00000143919 Calmodulin-lysine N-methyltransferase 2 44361950-44772592 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067912 Supported Nucleus Expressed in all testis: 24.4 -ABCG8 GBD4 ENSG00000143921 ATP-binding cassette, sub-family G (WHITE), member 8 2 43838964-43878466 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019556 Uncertain Uncertain Vesicles Group enriched 25 duodenum: 51.4;liver: 34.1;small intestine: 56.7 gallbladder: 1.8 -EML4 C2orf2, ELP120, ROPP120 ENSG00000143924 Echinoderm microtubule associated protein like 4 2 42169350-42332548 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036687, HPA036688, HPA065337 Supported Supported Intermediate filaments
Microtubules
Cytosol Mixed placenta: 50.1 -CALM2 CAMII, PHKD ENSG00000143933 Calmodulin 2 (phosphorylase kinase, delta) 2 47160082-47176601 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level CAB007790, HPA044999 Approved Expressed in all cerebral cortex: 1537.9 -CHAC2 ENSG00000143942 ChaC, cation transport regulator homolog 2 (E. coli) 2 53767792-53775196 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049235 Approved Approved Cytosol Mixed testis: 9.9 -RPS27A S27A, Uba80, UBCEP80 ENSG00000143947 Ribosomal protein S27a 2 55231903-55235853 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033319, HPA041344, HPA049132, HPA054087 Supported Approved Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 3409.3 -WDPCP BBS15, C2orf86, fritz, hFrtz ENSG00000143951 WD repeat containing planar cell polarity effector 2 63121383-63827843 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044144 Uncertain Approved Cell Junctions Mixed testis: 11.9 -VPS54 HCC8, PPP1R164 ENSG00000143952 Vacuolar protein sorting 54 homolog (S. cerevisiae) 2 63892146-64019072 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055894, HPA067981, HPA070582 Validated Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 58.8 -REG3G LPPM429, PAP1B, UNQ429 ENSG00000143954 Regenerating islet-derived 3 gamma 2 79025686-79028505 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047894, HPA048334, HPA060705 Uncertain Approved Cytosol Group enriched 15 epididymis: 198.2;testis: 107.1 pancreas: 10.0 -ASXL2 ASXH2, FLJ10898, KIAA1685 ENSG00000143970 Additional sex combs like transcriptional regulator 2 2 25733753-25878516 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034646, HPA058040 Validated Nucleoplasm Expressed in all parathyroid gland: 26.1 -ETAA1 ETAA16 ENSG00000143971 Ewing tumor-associated antigen 1 2 67397319-67410545 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035048, HPA035049 Uncertain Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 15.6 -SNRPG Sm-G ENSG00000143977 Small nuclear ribonucleoprotein polypeptide G 2 70281362-70293771 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064152, HPA067814 Supported Approved Nucleoplasm Expressed in all epididymis: 114.2 -ABHD1 FLJ36128, LABH1 ENSG00000143994 Abhydrolase domain containing 1 2 27123789-27130812 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA044390 Uncertain Tissue enriched 17 testis: 29.9 liver: 1.7 -MEIS1 ENSG00000143995 Meis homeobox 1 2 66433452-66573869 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011521, HPA056000, HPA058641 Approved Supported Nucleoplasm Expressed in all endometrium: 91.8 -TRIM43 TRIM43A ENSG00000144015 Tripartite motif containing 43 2 95592018-95599778 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA042223, HPA042772 Uncertain Not detected testis: 0.8 -CIAO1 CIA1, WDR39 ENSG00000144021 Cytosolic iron-sulfur assembly component 1 2 96266132-96273349 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017882 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 39.6 -ZNF514 FLJ14457 ENSG00000144026 Zinc finger protein 514 2 95147330-95165413 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028974 Approved Approved Nucleoplasm
Nuclear bodies Expressed in all epididymis: 32.4 -SNRNP200 ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD ENSG00000144028 Small nuclear ribonucleoprotein 200kDa (U5) 2 96274336-96305515 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029321 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 114.3 -MRPS5 MRP-S5, S5mt ENSG00000144029 Mitochondrial ribosomal protein S5 2 95087207-95149434 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055765 Approved Supported Mitochondria Expressed in all kidney: 37.4 -ANKRD53 FLJ12056, FLJ36160 ENSG00000144031 Ankyrin repeat domain 53 2 70978380-70985499 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049574 Approved Tissue enhanced 0 testis: 17.5 adipose tissue: 4.3 -TPRKB CGI-121 ENSG00000144034 TP53RK binding protein 2 73729104-73737400 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035712 Approved Supported Cytosol Expressed in all testis: 79.3 -NAT8 ATase2, GLA, Hcml1, TSC501 ENSG00000144035 N-acetyltransferase 8 (GCN5-related, putative) 2 73640832-73642393 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB045990, HPA074519 Uncertain Approved Endoplasmic reticulum Tissue enriched 18 kidney: 885.6 liver: 49.4 -EXOC6B KIAA0919, SEC15B, SEC15L2 ENSG00000144036 Exocyst complex component 6B 2 72175984-72826041 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034546, HPA063991 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Mixed cerebral cortex: 33.7 -SFXN5 BBG-TCC ENSG00000144040 Sideroflexin 5 2 72942036-73075619 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015473, HPA056866 Approved Approved Nucleoplasm
Mitochondria Tissue enhanced 0 cerebral cortex: 39.5 epididymis: 18.2 -TEX261 MGC32043, TEG-261 ENSG00000144043 Testis expressed 261 2 70985938-70994945 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA016631 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 91.4 -DQX1 FLJ23757 ENSG00000144045 DEAQ box RNA-dependent ATPase 1 2 74518131-74526336 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039158 Supported Approved Plasma membrane
Cytosol Tissue enhanced 0 duodenum: 14.8;small intestine: 13.8 colon: 5.6 -DUSP11 PIR1 ENSG00000144048 Dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2 73762184-73780157 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021052 Supported Nucleus
Nucleoli fibrillar center
Cytokinetic bridge Expressed in all fallopian tube: 61.9 -ST6GAL2 KIAA1877, SIAT2, St6gal2, St6GalII ENSG00000144057 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 2 106801600-106887108 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA014459 Uncertain Approved Nucleus
Nucleoli fibrillar center Tissue enhanced 0 cerebral cortex: 22.2;thyroid gland: 47.8 testis: 9.9 -NPHP1 JBTS4, NPH1, SLSN1 ENSG00000144061 Nephronophthisis 1 (juvenile) 2 110122311-110205066 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046093, HPA074071 Uncertain Uncertain Vesicles Tissue enhanced 0 testis: 45.7 fallopian tube: 28.1 -MALL BENE ENSG00000144063 Mal, T-cell differentiation protein-like 2 110083870-110116566 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051410 Uncertain Tissue enhanced 0 esophagus: 224.1;parathyroid gland: 315.0 small intestine: 186.2 -THNSL2 FLJ10916, SOFAT, TSH2 ENSG00000144115 Threonine synthase-like 2 2 88170295-88186636 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035395 Approved Tissue enhanced 0 parathyroid gland: 72.9 thyroid gland: 38.0 -RALB ENSG00000144118 V-ral simian leukemia viral oncogene homolog B 2 120240064-120294713 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026010, HPA065232 Approved Tissue enriched 8 parathyroid gland: 655.3 placenta: 82.2 -C1QL2 C1QTNF10, CTRP10 ENSG00000144119 Complement component 1, q subcomponent-like 2 2 119156243-119158889 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057934 Uncertain Tissue enriched 17 cerebral cortex: 2.5 testis: 0.1 -TMEM177 MGC10993 ENSG00000144120 Transmembrane protein 177 2 119679167-119686507 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036689, HPA053816 Uncertain Approved Nucleus
Nucleoli fibrillar center Mixed duodenum: 16.9 -NT5DC4 ENSG00000144130 5'-nucleotidase domain containing 4 2 112721486-112742879 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046856 Uncertain Tissue enriched 7 testis: 3.5 lymph node: 0.5 -RABL2A ENSG00000144134 RAB, member of RAS oncogene family-like 2A 2 113627229-113643396 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042700, HPA044007 Approved Uncertain Plasma membrane
Cytosol Tissue enhanced 0 fallopian tube: 31.0 cerebral cortex: 8.1 -SLC20A1 Glvr-1, GLVR1, PiT-1 ENSG00000144136 Solute carrier family 20 (phosphate transporter), member 1 2 112645857-112663827 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019279, HPA035834 Approved Approved Vesicles Expressed in all colon: 51.9 -FBLN7 FLJ37440, TM14 ENSG00000144152 Fibulin 7 2 112138385-112188216 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA034992 Uncertain Approved Plasma membrane
Cell Junctions Mixed parathyroid gland: 18.3 -ZC3H8 Fliz1, ZC3HDC8 ENSG00000144161 Zinc finger CCCH-type containing 8 2 112211525-112255136 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034803, HPA034804 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 16.2 -LIPT1 MGC12290, MGC13378 ENSG00000144182 Lipoyltransferase 1 2 99154955-99163157 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034802 Approved Expressed in all testis: 24.2 -CNGA3 ACHM2, CCNC1, CCNCa, CNCG3, CNG3 ENSG00000144191 Cyclic nucleotide gated channel alpha 3 2 98346155-98398601 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed esophagus: 1.9 -FAHD2B DKFZp434N062 ENSG00000144199 Fumarylacetoacetate hydrolase domain containing 2B 2 97083583-97094882 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042145, HPA044987 Approved Expressed in all epididymis: 47.9 -LYG1 SALW1939 ENSG00000144214 Lysozyme G-like 1 2 99284238-99304742 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 5 kidney: 21.9;testis: 4.8 breast: 2.5 -AFF3 LAF4, MLLT2-like ENSG00000144218 AF4/FMR2 family, member 3 2 99545419-100142739 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044512, HPA053379 Approved Supported Nucleoplasm
Cytosol Mixed prostate: 27.1 -UBXN4 KIAA0242, UBXD2, UBXDC1 ENSG00000144224 UBX domain protein 4 2 135741619-135785055 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036325 Approved Supported Endoplasmic reticulum Expressed in all thyroid gland: 104.6 -NXPH2 NPH2 ENSG00000144227 Neurexophilin 2 2 138670772-138780348 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA034759 Approved Group enriched 9 cerebral cortex: 5.7;kidney: 5.0;ovary: 13.9 endometrium: 0.9 -SPOPL BTBD33 ENSG00000144228 Speckle-type POZ protein-like 2 138501801-138573547 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA034687 Uncertain Approved Vesicles Expressed in all breast: 16.0 -THSD7B KIAA1679 ENSG00000144229 Thrombospondin, type I, domain containing 7B 2 136765545-137677717 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051416, HPA056745 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 epididymis: 5.0 adipose tissue: 2.0 -GPR17 ENSG00000144230 G protein-coupled receptor 17 2 127645864-127652639 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029766 Approved Approved Vesicles Mixed spleen: 12.3 -POLR2D RBP4 ENSG00000144231 Polymerase (RNA) II (DNA directed) polypeptide D 2 127843551-127858157 Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034694, HPA046092 Approved Supported Nucleoplasm
Nuclear speckles Tissue enriched 5 testis: 133.3 tonsil: 25.4 -AMMECR1L MGC4268 ENSG00000144233 AMMECR1-like 2 127861630-127885922 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000590, HPA057234 Uncertain Approved Nucleus
Cytosol Expressed in all testis: 26.2 -GALNT13 GalNAc-T13, KIAA1918 ENSG00000144278 Polypeptide N-acetylgalactosaminyltransferase 13 2 153871913-154453849 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA060775 Approved Group enriched 6 adrenal gland: 6.6;cerebral cortex: 32.8 lung: 3.2 -PKP4 p0071 ENSG00000144283 Plakophilin 4 2 158456964-158682879 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037334, HPA066647, HPA070648 Approved Validated Plasma membrane
Cell Junctions Expressed in all kidney: 65.1 -SCN1A FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI ENSG00000144285 Sodium channel, voltage gated, type I alpha subunit 2 165989160-166128047 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA078664 Approved Nucleoplasm
Nuclear bodies
Plasma membrane Tissue enhanced 0 cerebral cortex: 12.0;fallopian tube: 4.4;lung: 3.2 testis: 2.2 -SLC4A10 NBCn2, NCBE ENSG00000144290 Solute carrier family 4, sodium bicarbonate transporter, member 10 2 161424332-161985282 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA034755 Supported Tissue enriched 22 cerebral cortex: 57.7 adrenal gland: 2.6 -SCRN3 FLJ23142 ENSG00000144306 Secernin 3 2 174395730-174429575 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034689, HPA034690 Approved Approved Vesicles
Cytosol Expressed in all parathyroid gland: 47.7 -KIAA1715 LNP, LNP1, Ul, ulnaless ENSG00000144320 KIAA1715 2 175923892-176002839 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014205 Approved Supported Nucleoplasm
Endoplasmic reticulum Expressed in all testis: 45.8 -ZNF385B FLJ25270, ZNF533 ENSG00000144331 Zinc finger protein 385B 2 179441982-179861505 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046086 Supported Nucleoli fibrillar center Tissue enhanced 0 lung: 27.4 prostate: 20.7 -TMEFF2 CT120.2, HPP1, TENB2, TPEF, TR ENSG00000144339 Transmembrane protein with EGF-like and two follistatin-like domains 2 2 191949043-192195709 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015587 Uncertain Approved Microtubules
Cytokinetic bridge Tissue enhanced 0 cerebral cortex: 41.1;prostate: 54.9;seminal vesicle: 19.4 epididymis: 10.5 -CDCA7 FLJ14736, JPO1 ENSG00000144354 Cell division cycle associated 7 2 173354820-173368997 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005565 Uncertain Supported Nucleoplasm
Cytosol Mixed lymph node: 45.2 -DLX1 ENSG00000144355 Distal-less homeobox 1 2 172084740-172089677 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035666, HPA045884 Approved Approved Nucleus
Vesicles
Cell Junctions Tissue enhanced 0 adrenal gland: 1.6;cerebral cortex: 5.0 prostate: 0.7 -UBR3 DKFZp434P117, FLJ37422, KIAA2024, ZNF650 ENSG00000144357 Ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 169827458-170084131 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035390 Approved Approved Nucleus
Nucleoli Expressed in all parathyroid gland: 38.9 -PHOSPHO2 MGC22679 ENSG00000144362 Phosphatase, orphan 2 2 169694454-169701708 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA034726, HPA034727 Uncertain Approved Vesicles Expressed in all testis: 22.9 -GULP1 CED-6, CED6, GULP ENSG00000144366 GULP, engulfment adaptor PTB domain containing 1 2 188291669-188595931 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020587 Approved Approved Vesicles Mixed epididymis: 98.7 -FAM171B FLJ34104, KIAA1946 ENSG00000144369 Family with sequence similarity 171, member B 2 186693971-186765965 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA010639, HPA013434 Approved Approved Nucleus
Mitochondria Tissue enriched 6 cerebral cortex: 114.9 parathyroid gland: 19.0 -HSPD1 GroEL, HSP60, SPG13 ENSG00000144381 Heat shock 60kDa protein 1 (chaperonin) 2 197486581-197516737 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001523, CAB002775, HPA050025, CAB072816 Supported Validated Mitochondria Expressed in all adrenal gland: 838.0 -CCDC150 FLJ39660 ENSG00000144395 Coiled-coil domain containing 150 2 196639554-196763490 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043968, HPA048104 Uncertain Approved Nucleoplasm Group enriched 9 kidney: 2.6;testis: 8.8 liver: 0.6 -METTL21A FAM119A, HCA557b, HSPA-KMT, LOC151194 ENSG00000144401 Methyltransferase like 21A 2 207580631-207625928 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034712 Uncertain Approved Nucleus
Cytosol Expressed in all spleen: 22.4 -UNC80 C2orf21, FLJ33496, KIAA1843, UNC-80 ENSG00000144406 Unc-80 homolog (C. elegans) 2 209771993-209999300 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042472 Approved Approved Vesicles Tissue enhanced 0 adrenal gland: 5.1;cerebral cortex: 15.8;testis: 5.2 gallbladder: 1.9 -PTH2R PTHR2 ENSG00000144407 Parathyroid hormone 2 receptor 2 208359714-208854503 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA010655 Approved Mixed bone marrow: 2.9 -CPO ENSG00000144410 Carboxypeptidase O 2 206939554-206969474 Enzymes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 15 small intestine: 133.7 epididymis: 9.2 -NBEAL1 ALS2CR16, ALS2CR17, MGC164581 ENSG00000144426 Neurobeachin-like 1 2 203014879-203226378 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049189, HPA049447 Uncertain Approved Nucleoplasm
Cytosol Mixed thyroid gland: 7.6 -KANSL1L C2orf67, FLJ23861, FLJ32349, KIAA1267L, MSL1v2 ENSG00000144445 KAT8 regulatory NSL complex subunit 1-like 2 210021423-210171383 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043102, HPA046790 Uncertain Approved Cytosol Tissue enriched 12 parathyroid gland: 575.5 testis: 46.2 -SPAG16 DKFZp666P1710, FLJ22724, PF20, WDR29 ENSG00000144451 Sperm associated antigen 16 2 213284379-214410501 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037542 Uncertain Approved Plasma membrane
Cytosol Expressed in all testis: 83.8 -ABCA12 DKFZP434G232, ICR2B, LI2 ENSG00000144452 ATP-binding cassette, sub-family A (ABC1), member 12 2 214931542-215138428 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 breast: 7.5;skin: 25.3 tonsil: 2.6 -SUMF1 FGE, UNQ3037 ENSG00000144455 Sulfatase modifying factor 1 3 3700814-4467281 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038025 Uncertain Expressed in all parathyroid gland: 71.1 -NYAP2 KIAA1486 ENSG00000144460 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 2 225400648-225654018 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045531 Uncertain Approved Nucleoplasm
Intermediate filaments Tissue enriched 6 cerebral cortex: 1.9 lung: 0.3 -RHBDD1 DKFZp547E052 ENSG00000144468 Rhomboid domain containing 1 2 226835581-226999215 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013972, HPA057125 Approved Supported Endoplasmic reticulum Expressed in all testis: 32.2 -ACKR3 CMKOR1, CXCR7, GPR159, RDC1 ENSG00000144476 Atypical chemokine receptor 3 2 236567787-236582358 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032003, HPA049718 Approved Supported Vesicles
Plasma membrane Expressed in all placenta: 175.2 -TRPM8 ENSG00000144481 Transient receptor potential cation channel, subfamily M, member 8 2 233917398-234019522 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 8 prostate: 128.7 liver: 16.3 -HES6 bHLHb41 ENSG00000144485 Hes family bHLH transcription factor 6 2 238238267-238240662 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA061763 Approved Nucleus
Nucleoli
Nuclear bodies
Cytosol Tissue enhanced 0 cerebral cortex: 77.0 fallopian tube: 22.1 -ESPNL FLJ42568 ENSG00000144488 Espin-like 2 238100157-238133287 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055103 Uncertain Mixed seminal vesicle: 1.2 -ANKMY1 FLJ20499, ZMYND13 ENSG00000144504 Ankyrin repeat and MYND domain containing 1 2 240479422-240569209 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA026620 Uncertain Approved Nucleus
Nuclear bodies
Cytosol Group enriched 7 fallopian tube: 39.0;testis: 118.1 parathyroid gland: 11.0 -COPS7B CSN7B ENSG00000144524 COP9 signalosome subunit 7B 2 231781671-231809254 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034675, HPA034676 Uncertain Supported Nucleoplasm Expressed in all testis: 37.2 -DIS3L2 FAM6A, FLJ36974, MGC42174 ENSG00000144535 DIS3 like 3'-5' exoribonuclease 2 2 231961245-232344350 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035796, HPA035797 Approved Expressed in all parathyroid gland: 28.8 -CPNE9 KIAA4217 ENSG00000144550 Copine family member IX 3 9703807-9729908 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 5 cerebral cortex: 12.6 testis: 2.4 -FANCD2 FA-D2, FACD, FAD, FANCD ENSG00000144554 Fanconi anemia, complementation group D2 3 10026414-10101930 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016117, HPA063742 Approved Supported Nucleus
Nuclear bodies
Cytosol Mixed testis: 21.7 -TAMM41 C3orf31, DKFZp434E0519, MGC16471 ENSG00000144559 TAM41 mitochondrial translocator assembly and maintenance homolog 3 11790442-11846919 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036834, HPA044861 Uncertain Approved Cytosol Mixed epididymis: 11.5 -VGLL4 KIAA0121 ENSG00000144560 Vestigial-like family member 4 3 11556070-11771350 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038225, HPA038614 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all ovary: 110.5 -RAB5A RAB5 ENSG00000144566 RAB5A, member RAS oncogene family 3 19947079-19985175 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004567, HPA049354 Approved Expressed in all parathyroid gland: 78.1 -FAM134A C2orf17, MGC3035 ENSG00000144567 Family with sequence similarity 134, member A 2 219176225-219185479 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011170, HPA011844 Approved Approved Cytosol Expressed in all testis: 142.9 -CTDSP1 NLIIF, SCP1 ENSG00000144579 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 2 218398256-218405941 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062654 Supported Nucleoplasm Expressed in all placenta: 106.2 -RQCD1 CAF40, CNOT9, CT129, RCD1, RCD1+ ENSG00000144580 RCD1 required for cell differentiation1 homolog (S. pombe) 2 218568580-218597080 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046622 Approved Expressed in all testis: 48.8 -MARCH4 KIAA1399, MARCH-IV, RNF174 ENSG00000144583 Membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase 2 216257865-216372027 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014348 Approved Tissue enriched 6 cerebral cortex: 9.1 stomach: 1.6 -STK11IP KIAA1898, LIP1, LKB1IP, STK11IP1 ENSG00000144589 Serine/threonine kinase 11 interacting protein 2 219597860-219616451 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036837, HPA036838, HPA053192 Approved Validated Vesicles Expressed in all testis: 39.7 -GMPPA ENSG00000144591 GDP-mannose pyrophosphorylase A 2 219498867-219506989 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035512, HPA035513 Approved Approved Nucleoplasm Expressed in all epididymis: 82.6 -GRIP2 KIAA1719 ENSG00000144596 Glutamate receptor interacting protein 2 3 14489111-14542081 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA035673 Approved Cytosol Tissue enhanced 0 heart muscle: 5.4;skeletal muscle: 7.3 placenta: 3.9 -EAF1 ENSG00000144597 ELL associated factor 1 3 15427355-15450635 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059516, HPA060569, HPA069538 Supported Validated Nucleoplasm
Nuclear bodies
Vesicles Expressed in all bone marrow: 33.7 -CNTN4 BIG-2 ENSG00000144619 Contactin 4 3 2098813-3057956 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 parathyroid gland: 47.8 testis: 24.1 -DYNC1LI1 DNCLI1 ENSG00000144635 Dynein, cytoplasmic 1, light intermediate chain 1 3 32525971-32570874 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035013 Approved Supported Centrosome
Cytosol Expressed in all testis: 74.0 -RBMS3 ENSG00000144642 RNA binding motif, single stranded interacting protein 3 3 29280982-30010391 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034719 Uncertain Approved Vesicles Mixed thyroid gland: 27.9 -GADL1 ENSG00000144644 Glutamate decarboxylase-like 1 3 30726200-30894765 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039160, HPA040229 Uncertain Approved Plasma membrane
Cytosol Tissue enhanced 0 skeletal muscle: 9.0 thyroid gland: 2.5 -OSBPL10 ENSG00000144645 Oxysterol binding protein-like 10 3 31657890-32077580 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003636 Approved Golgi apparatus
Plasma membrane
Cytosol Mixed testis: 31.7 -POMGNT2 AGO61, C3orf39, FLJ14566, GTDC2 ENSG00000144647 Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 3 43079232-43106076 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034870, HPA040989 Uncertain Expressed in all endometrium: 35.6 -ACKR2 CCBP2, CCR10, CCR9, CMKBR9, D6 ENSG00000144648 Atypical chemokine receptor 2 3 42804752-42887974 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013819, HPA073493 Supported Supported Nucleoplasm
Vesicles
Cytosol Tissue enhanced 0 placenta: 22.8 adipose tissue: 5.2 -FAM198A C3orf41, DKFZP434B172 ENSG00000144649 Family with sequence similarity 198, member A 3 42979267-43060211 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047726 Approved Supported Vesicles Mixed fallopian tube: 15.5 -CSRNP1 AXUD1, DKFZp566F164, FAM130B, TAIP-3, URAX1 ENSG00000144655 Cysteine-serine-rich nuclear protein 1 3 39141855-39154562 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA045207, HPA058463 Validated Nucleoplasm
Vesicles Expressed in all bone marrow: 123.7 -SLC25A38 FLJ20551 ENSG00000144659 Solute carrier family 25, member 38 3 39383348-39397351 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041027 Approved Expressed in all thyroid gland: 65.8 -ITGA9 ALPHA-RLC, ITGA4L, RLC ENSG00000144668 Integrin, alpha 9 3 37452115-37823514 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030609 Approved Approved Nucleus
Vesicles Mixed thyroid gland: 34.5 -SLC22A14 OCTL2, ORCTL4 ENSG00000144671 Solute carrier family 22, member 14 3 38282294-38318575 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 20 testis: 13.4 kidney: 0.6 -GOLGA4 GCP2, GOLG, golgin-240, p230 ENSG00000144674 Golgin A4 3 37243177-37366751 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035102 Supported Supported Golgi apparatus
Vesicles
Cytosol Expressed in all testis: 80.6 -CTDSPL C3orf8, HYA22, PSR1, RBSP3, SCP3 ENSG00000144677 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 3 37861960-37984469 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048325 Approved Approved Nucleoplasm
Vesicles Expressed in all skin: 65.8 -STAC STAC1 ENSG00000144681 SH3 and cysteine rich domain 3 36380344-36548007 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA035143 Uncertain Uncertain Nucleoplasm
Plasma membrane Tissue enhanced 0 parathyroid gland: 23.0;prostate: 20.0 lung: 15.8 -IQSEC1 ARF-GEP100, BRAG2, GEP100, KIAA0763 ENSG00000144711 IQ motif and Sec7 domain 1 3 12897220-13073117 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038143, HPA038144 Uncertain Approved Nucleoli
Vesicles Expressed in all cerebral cortex: 83.6 -CAND2 KIAA0667, TIP120B, Tp120b ENSG00000144712 Cullin-associated and neddylation-dissociated 2 (putative) 3 12796472-12871916 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005777 Approved Approved Nuclear bodies
Cytosol Tissue enhanced 0 skeletal muscle: 42.3;testis: 32.9 heart muscle: 16.2 -RPL32 L32 ENSG00000144713 Ribosomal protein L32 3 12834485-12841588 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047501, HPA051994 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all ovary: 4499.5 -PTPRG PTPG, RPTPG ENSG00000144724 Protein tyrosine phosphatase, receptor type, G 3 61561569-62297613 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064237 Uncertain Tissue enhanced 0 parathyroid gland: 78.3 thyroid gland: 24.1 -IL17RD FLJ35755, IL-17RD, IL17RLM, SEF ENSG00000144730 Interleukin 17 receptor D 3 57089982-57170306 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039577, HPA043550 Approved Supported Nucleoplasm
Golgi apparatus Mixed parathyroid gland: 26.3 -SHQ1 FLJ10539, Shq1p ENSG00000144736 SHQ1, H/ACA ribonucleoprotein assembly factor 3 72749277-72861914 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042792 Uncertain Supported Nucleoplasm Expressed in all testis: 18.0 -SLC25A26 ENSG00000144741 Solute carrier family 25 (S-adenosylmethionine carrier), member 26 3 66133610-66388116 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA026887 Supported Supported Mitochondria Expressed in all thyroid gland: 17.4 -UBA3 hUba3, NAE2, UBE1C ENSG00000144744 Ubiquitin-like modifier activating enzyme 3 3 69054730-69080408 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034873, HPA034874, HPA065335 Supported Approved Nucleoplasm
Plasma membrane
Centrosome
Cytosol Expressed in all bone marrow: 68.1 -ARL6IP5 DERP11, GTRAP3-18, HSPC127, JWA, PRAF3 ENSG00000144746 ADP-ribosylation factor-like 6 interacting protein 5 3 69084944-69106066 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015540, CAB019321 Supported Approved Endoplasmic reticulum Expressed in all prostate: 217.5 -TMF1 ARA160, TMF ENSG00000144747 TATA element modulatory factor 1 3 69019827-69052303 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008729 Approved Supported Golgi apparatus Expressed in all testis: 59.3 -LRIG1 DKFZP586O1624, LIG-1, LIG1 ENSG00000144749 Leucine-rich repeats and immunoglobulin-like domains 1 3 66378797-66501263 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011846 Approved Approved Cytosol Expressed in all cerebral cortex: 59.8 -LRTM1 HT017 ENSG00000144771 Leucine-rich repeats and transmembrane domains 1 3 54918237-54967088 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA013839 Uncertain Group enriched 5 esophagus: 4.3;skeletal muscle: 9.1;spleen: 9.0 prostate: 1.4 -RP11-977G19.10 ENSG00000144785 12 56285916-56316059 Predicted secreted proteins Evidence at protein level Evidence at protein level HPA038466 Uncertain Mixed colon: 8.0 -LIMD1 ENSG00000144791 LIM domains containing 1 3 45555394-45686338 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064220 Supported Nucleus
Focal adhesion sites Expressed in all lung: 26.8 -ZNF660 FLJ36870 ENSG00000144792 Zinc finger protein 660 3 44578223-44599694 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA029705 Uncertain Uncertain Nucleoli fibrillar center
Cytosol Mixed ovary: 3.1 -NFKBIZ FLJ34463, INAP, MAIL ENSG00000144802 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 3 101827991-101861022 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010547, HPA075363 Supported Supported Nuclear speckles
Cytoplasmic bodies Expressed in all bone marrow: 269.0 -COL8A1 C3orf7, MGC9568 ENSG00000144810 Collagen, type VIII, alpha 1 3 99638475-99799226 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053107 Supported Supported Vesicles Tissue enhanced 0 parathyroid gland: 87.2 lung: 57.1 -NXPE3 FAM55C, MGC15606 ENSG00000144815 Neurexophilin and PC-esterase domain family, member 3 3 101779202-101828229 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036259 Uncertain Approved Nucleoplasm
Vesicles Mixed parathyroid gland: 34.2 -ADGRG7 FLJ14454, GPR128 ENSG00000144820 Adhesion G protein-coupled receptor G7 3 100609589-100695479 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 duodenum: 44.0;liver: 12.4;small intestine: 43.8 colon: 5.4 -MYH15 KIAA1000 ENSG00000144821 Myosin, heavy chain 15 3 108380369-108529322 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034871 Uncertain Approved Nucleoplasm
Centrosome
Mitochondria Tissue enhanced 0 cerebral cortex: 1.9 rectum: 1.3 -PHLDB2 FLJ21791, LL5b, LL5beta ENSG00000144824 Pleckstrin homology-like domain, family B, member 2 3 111732497-111976517 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035146, HPA035147 Approved Supported Plasma membrane
Cytosol Mixed placenta: 59.4 -ABHD10 FLJ11342 ENSG00000144827 Abhydrolase domain containing 10 3 111979010-111993363 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036991, HPA036992, HPA066081 Supported Approved Mitochondria Expressed in all epididymis: 61.2 -TAGLN3 NP22, NP25 ENSG00000144834 Transgelin 3 3 111998664-112013887 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062620 Supported Tissue enriched 8 cerebral cortex: 357.2 adrenal gland: 42.7 -PLA1A ps-PLA1 ENSG00000144837 Phospholipase A1 member A 3 119597842-119629811 Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059740 Approved Nuclear speckles Tissue enhanced 0 epididymis: 162.2;seminal vesicle: 92.2 parathyroid gland: 38.1 -RABL3 MGC23920 ENSG00000144840 RAB, member of RAS oncogene family-like 3 3 120686681-120742993 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035150, HPA035151 Uncertain Approved Nucleoplasm Expressed in all thyroid gland: 32.9 -ADPRH ARH1 ENSG00000144843 ADP-ribosylarginine hydrolase 3 119579268-119589945 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001701, HPA036961 Approved Approved Nucleus
Nuclear membrane Mixed lung: 20.2 -IGSF11 BT-IgSF, CT119, Igsf13, MGC35227, VSIG3 ENSG00000144847 Immunoglobulin superfamily, member 11 3 118900557-119146068 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046377 Uncertain Approved Nucleus
Cell Junctions
Cytosol Tissue enhanced 0 cerebral cortex: 31.1;testis: 64.7 ovary: 20.0 -ATG3 APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96 ENSG00000144848 Autophagy related 3 3 112532509-112562046 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037260, HPA040471 Supported Supported Plasma membrane
Cytosol Expressed in all testis: 154.2 -NR1I2 BXR, ONR1, PAR2, PXR, SXR ENSG00000144852 Nuclear receptor subfamily 1, group I, member 2 3 119780484-119818485 FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA029309, HPA055121, HPA073926 Validated Nucleoplasm Group enriched 12 colon: 9.3;duodenum: 23.2;gallbladder: 6.0;liver: 19.7;rectum: 9.4;small intestine: 26.3 stomach: 1.3 -BOC CDON2 ENSG00000144857 BOC cell adhesion associated, oncogene regulated 3 113211003-113287459 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025806, HPA060778, HPA061787 Uncertain Supported Nucleoplasm
Plasma membrane Mixed fallopian tube: 56.6 -SRPRB APMCF1 ENSG00000144867 Signal recognition particle receptor, B subunit 3 133784033-133825772 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011173 Approved Approved Plasma membrane Expressed in all epididymis: 51.1 -TMEM108 CT124, MGC3040 ENSG00000144868 Transmembrane protein 108 3 133038391-133397792 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA063350 Uncertain Approved Nucleoli
Vesicles
Cytosol Tissue enhanced 0 testis: 25.8 cerebral cortex: 22.0 -AGTR1 AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R ENSG00000144891 Angiotensin II receptor, type 1 3 148697784-148743008 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA003596 Supported Uncertain Vesicles Tissue enhanced 0 placenta: 212.0 liver: 50.8 -MED12L KIAA1635, TNRC11L, TRALP, TRALPUSH ENSG00000144893 Mediator complex subunit 12-like 3 151085697-151437072 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036807 Uncertain Approved Nucleoli Tissue enhanced 0 cerebral cortex: 26.7 testis: 8.6 -EIF2A EIF-2A ENSG00000144895 Eukaryotic translation initiation factor 2A, 65kDa 3 150546678-150584242 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036256 Approved Approved Mitochondria
Cytosol Expressed in all thyroid gland: 141.7 -ALDH1L1 10-fTHF, FTHFD ENSG00000144908 Aldehyde dehydrogenase 1 family, member L1 3 126103562-126197994 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036900, HPA050139 Approved Supported Cytosol Tissue enhanced 0 kidney: 123.5;liver: 191.5 adipose tissue: 82.2 -OSBPL11 FLJ13012, FLJ13164, ORP-11, ORP11 ENSG00000144909 Oxysterol binding protein-like 11 3 125528858-125595090 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039144 Approved Nucleoplasm
Golgi apparatus Mixed spleen: 23.2 -TRPC1 HTRP-1 ENSG00000144935 Transient receptor potential cation channel, subfamily C, member 1 3 142724074-142807888 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009387, HPA021130 Supported Approved Vesicles Mixed endometrium: 18.5 -NCEH1 AADACL1, KIAA1363, NCEH ENSG00000144959 Neutral cholesterol ester hydrolase 1 3 172630249-172711218 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026888 Supported Approved Endoplasmic reticulum Mixed cerebral cortex: 35.1 -SPATA16 NYD-SP12 ENSG00000144962 Spermatogenesis associated 16 3 172889358-173141268 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037884 Supported Tissue enriched 609 testis: 105.0 kidney: 0.1 -FAM86B2 ENSG00000145002 Family with sequence similarity 86, member B2 8 12425614-12436343 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041610, HPA055718 Uncertain Uncertain Vesicles Tissue enhanced 0 fallopian tube: 4.6 thyroid gland: 2.3 -LPP ENSG00000145012 LIM domain containing preferred translocation partner in lipoma 3 188153284-188890671 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011133, HPA017342 Supported Validated Focal adhesion sites
Cytosol Expressed in all smooth muscle: 116.9 -TMEM44 DKFZp686O18124 ENSG00000145014 Transmembrane protein 44 3 194587673-194633689 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA043718 Uncertain Approved Cytosol Mixed epididymis: 15.8 -RUBCN KIAA0226, rubicon, rundataxin ENSG00000145016 RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein 3 197671393-197749727 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050908, HPA054497 Approved Supported Vesicles
Cytosol Expressed in all spleen: 24.7 -AMT GCST, NKH ENSG00000145020 Aminomethyltransferase 3 49416778-49422753 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005566 Supported Supported Nucleoplasm
Mitochondria Expressed in all endometrium: 25.3 -TCTA ENSG00000145022 T-cell leukemia translocation altered 3 49412206-49416475 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA007342 Approved Approved Cytosol Expressed in all thyroid gland: 75.9 -NICN1 MGC12936 ENSG00000145029 Nicolin 1 3 49422946-49429326 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA037550, HPA058014 Uncertain Supported Nucleoplasm Expressed in all cerebral cortex: 32.0 -UCN2 SRP, UCN-II, UCNI, URP ENSG00000145040 Urocortin 2 3 48561727-48563773 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA066841 Uncertain Approved Vesicles Tissue enriched 8 skin: 15.6 endometrium: 2.0 -VPRBP DCAF1, KIAA0800, MGC102804 ENSG00000145041 Vpr (HIV-1) binding protein 3 51395867-51500002 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036142, HPA052445, HPA053203 Supported Validated Nucleus
Nucleoli fibrillar center Expressed in all testis: 96.6 -MANF ARMET, ARP ENSG00000145050 Mesencephalic astrocyte-derived neurotrophic factor 3 51385047-51389397 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA011175 Approved Supported Endoplasmic reticulum Expressed in all epididymis: 123.2 -CCDC39 CILD14, DKFZp434A128, FAP59 ENSG00000145075 Coiled-coil domain containing 39 3 180602858-180871005 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035363, HPA035364 Supported Mixed parathyroid gland: 27.7 -STXBP5L KIAA1006, LLGL4 ENSG00000145087 Syntaxin binding protein 5-like 3 120908072-121424761 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 15.7;ovary: 12.3;thyroid gland: 14.0 seminal vesicle: 4.7 -EAF2 BM040, TRAITS, U19 ENSG00000145088 ELL associated factor 2 3 121835183-121886526 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA008411 Supported Tissue enhanced 0 lymph node: 64.5 bone marrow: 47.9 -ILDR1 DFNB42, MGC50831 ENSG00000145103 Immunoglobulin-like domain containing receptor 1 3 121987323-122022204 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018207 Approved Tissue enhanced 0 parathyroid gland: 34.7 cervix: 20.0 -TM4SF19 ENSG00000145107 Transmembrane 4 L six family member 19 3 196319342-196338503 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 11.3 lung: 3.1 -MUC4 ENSG00000145113 Mucin 4, cell surface associated 3 195746765-195812277 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005895, CAB013536 Approved Tissue enhanced 0 colon: 1.1 esophagus: 0.4 -SLIT2 SLIL3, Slit-2 ENSG00000145147 Slit guidance ligand 2 4 20253260-20620561 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB007590, HPA019511, HPA023088 Uncertain Mixed lung: 49.5 -EIF2B5 EIF-2B, EIF2Bepsilon ENSG00000145191 Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 3 184135038-184684758 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015412, HPA064370, HPA069303 Uncertain Validated Cytosol Expressed in all parathyroid gland: 38.0 -AHSG A2HS, FETUA, HSGA ENSG00000145192 Alpha-2-HS-glycoprotein 3 186612923-186621318 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001524, HPA001525, CAB026209 Supported Supported Golgi apparatus Tissue enriched 1899 liver: 2819.2 testis: 1.4 -ECE2 KIAA0604, MGC2408 ENSG00000145194 Endothelin converting enzyme 2 3 184249650-184293031 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043346, HPA062215 Approved Approved Nucleus
Cytosol Mixed adrenal gland: 15.5 -VWA5B2 DKFZp761K032, LOC90113 ENSG00000145198 Von Willebrand factor A domain containing 5B2 3 184230429-184242329 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036823, HPA036824, HPA061412 Approved Approved Nucleus
Golgi apparatus Tissue enriched 10 adrenal gland: 53.7 cerebral cortex: 5.4 -DGKQ DAGK, DAGK4, DAGK7 ENSG00000145214 Diacylglycerol kinase, theta 110kDa 4 958887-986895 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026797, CAB033835 Uncertain Expressed in all small intestine: 26.6 -FIP1L1 DKFZp586K0717, FIP1 ENSG00000145216 Factor interacting with PAPOLA and CPSF1 4 53377643-53460861 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037475, HPA058202 Supported Validated Nucleoplasm Expressed in all testis: 68.7 -SLC26A1 EDM4, SAT-1 ENSG00000145217 Solute carrier family 26 (anion exchanger), member 1 4 979073-993440 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041654 Uncertain Approved Microtubules Mixed kidney: 6.1 -LYAR ZC2HC2, ZLYAR ENSG00000145220 Ly1 antibody reactive 4 4267701-4290169 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035881 Supported Supported Nucleus
Nucleoli Tissue enriched 7 testis: 185.2 lymph node: 27.9 -CENPC CENP-C, CENPC1, hcp-4, MIF2 ENSG00000145241 Centromere protein C 4 67468748-67545606 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049740, HPA058252 Validated Nucleoplasm
Nuclear bodies
Cytosol Mixed ovary: 6.1 -EPHA5 CEK7, EHK1, Hek7, TYRO4 ENSG00000145242 EPH receptor A5 4 65319563-65670495 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 5 cerebral cortex: 18.0 cervix: 3.3 -CORIN ATC2, CRN, Lrp4, PRSC, TMPRSS10 ENSG00000145244 Corin, serine peptidase 4 47593998-47838106 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA070941 Approved Nuclear bodies
Plasma membrane
Actin filaments Tissue enhanced 0 heart muscle: 45.0 skin: 9.5 -ATP10D ATPVD, KIAA1487 ENSG00000145246 ATPase, class V, type 10D 4 47485288-47593486 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA050808 Approved Supported Nucleoplasm
Plasma membrane Mixed parathyroid gland: 22.1 -OCIAD2 MGC45416 ENSG00000145247 OCIA domain containing 2 4 48885019-48906937 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040979, HPA041090 Supported Validated Mitochondria Expressed in all kidney: 150.6 -SLC10A4 MGC29802 ENSG00000145248 Solute carrier family 10, member 4 4 48483343-48489196 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028835 Uncertain Supported Tissue enhanced 0 adrenal gland: 6.2;cerebral cortex: 4.0 cervix: 1.5 -SLC10A6 SOAT ENSG00000145283 Solute carrier family 10 (sodium/bile acid cotransporter), member 6 4 86823468-86849263 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA016662 Supported Tissue enhanced 0 esophagus: 11.0;skin: 17.3 adipose tissue: 6.2 -SCD5 ACOD4, FADS4, FLJ21032, HSCD5, SCD4 ENSG00000145284 Stearoyl-CoA desaturase 5 4 82629539-82798857 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042380 Uncertain Tissue enhanced 0 adrenal gland: 201.7;cerebral cortex: 502.5 epididymis: 117.9 -PLAC8 C15, onzin ENSG00000145287 Placenta-specific 8 4 83090048-83137075 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040465, HPA077912 Supported Approved Cytosol Mixed bone marrow: 236.4 -ENOPH1 E1, MASA, mtnC ENSG00000145293 Enolase-phosphatase 1 4 82430562-82461091 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004985, HPA044607 Supported Approved Nucleoplasm
Nuclear bodies Expressed in all cerebral cortex: 98.6 -CABS1 C4orf35, CLPH, FLJ32897, NYD-SP26 ENSG00000145309 Calcium-binding protein, spermatid-specific 1 4 70334966-70337116 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044016, HPA055352 Supported Tissue enriched 591 testis: 150.7 salivary gland: 0.2 -GC DBP, hDBP, VDBP ENSG00000145321 Group-specific component (vitamin D binding protein) 4 71741693-71804041 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001526, CAB008596, HPA019855 Supported Tissue enriched 5 liver: 3869.8 gallbladder: 715.0 -TRMT10A MGC27034, RG9MTD2, TRM10 ENSG00000145331 TRNA methyltransferase 10A 4 99546709-99564032 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047601, HPA058241 Uncertain Approved Nucleoplasm
Nucleoli
Actin filaments
Cytosol Expressed in all testis: 21.1 -KLHL8 KIAA1378 ENSG00000145332 Kelch-like family member 8 4 87160103-87240314 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013856, HPA017762 Approved Validated Nucleoplasm Expressed in all epididymis: 72.6 -SNCA alpha-synuclein, NACP, PARK1, PARK4, PD1 ENSG00000145335 Synuclein, alpha (non A4 component of amyloid precursor) 4 89724099-89838315 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005459, CAB010877 Supported Group enriched 5 bone marrow: 161.2;cerebral cortex: 460.5 endometrium: 56.7 -PYURF PreY ENSG00000145337 PIGY upstream reading frame 4 88520985-88523813 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036455 Uncertain Approved Nucleoplasm Expressed in all epididymis: 93.7 -TBCK HSPC302, MGC16169 ENSG00000145348 TBC1 domain containing kinase 4 106041599-106321495 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039951, HPA051611 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center Mixed testis: 16.1 -CAMK2D CAMKD ENSG00000145349 Calcium/calmodulin-dependent protein kinase II delta 4 113451032-113761927 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026281, HPA051783, HPA051785, HPA053973 Approved Supported Plasma membrane
Cell Junctions Expressed in all parathyroid gland: 106.2 -CISD2 ERIS, Miner1, NAF-1, WFS2, ZCD2 ENSG00000145354 CDGSH iron sulfur domain 2 4 102868978-102889242 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015914 Approved Supported Endoplasmic reticulum Expressed in all thyroid gland: 61.7 -DDIT4L REDD2, Rtp801L ENSG00000145358 DNA-damage-inducible transcript 4-like 4 100185870-100190782 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA050903 Uncertain Nucleoplasm
Plasma membrane
Actin filaments Tissue enhanced 0 skeletal muscle: 113.3 cervix: 33.1 -ANK2 LQT4 ENSG00000145362 Ankyrin 2, neuronal 4 112818109-113383740 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008007, CAB015178, HPA035970 Supported Tissue enhanced 0 cerebral cortex: 184.9 kidney: 124.2 -TIFA MGC20791, T2BP, T6BP, TIFAA ENSG00000145365 TRAF-interacting protein with forkhead-associated domain 4 112274542-112285903 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045889 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all lymph node: 38.1 -SPATA5 AFG2, SPAF ENSG00000145375 Spermatogenesis associated 5 4 122923074-123319450 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036450, HPA036451 Approved Approved Cytosol Mixed testis: 4.2 -FABP2 I-FABP ENSG00000145384 Fatty acid binding protein 2, intestinal 4 119317250-119322390 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034607, CAB047325, CAB047326 Supported Approved Plasma membrane
Actin filaments
Cytosol Group enriched 12 duodenum: 268.5;small intestine: 565.3 rectum: 34.6 -CCNA2 CCN1, CCNA ENSG00000145386 Cyclin A2 4 121816444-121823933 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000114, HPA020626 Approved Validated Nucleoplasm
Cytosol Mixed lymph node: 29.6 -METTL14 KIAA1627 ENSG00000145388 Methyltransferase like 14 4 118685368-118715433 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038002 Supported Supported Nucleoplasm Expressed in all testis: 23.5 -USP53 KIAA1350 ENSG00000145390 Ubiquitin specific peptidase 53 4 119212587-119295517 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035844, HPA035845 Uncertain Approved Nucleoplasm
Golgi apparatus Mixed fallopian tube: 48.4 -SETD7 KIAA1717, KMT7, SET7, SET7/9, Set9 ENSG00000145391 SET domain containing (lysine methyltransferase) 7 4 139495941-139606699 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058111 Approved Supported Nucleoli Expressed in all parathyroid gland: 59.7 -NAF1 ENSG00000145414 Nuclear assembly factor 1 ribonucleoprotein 4 163110073-163166921 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036241, HPA036242, HPA066090 Approved Validated Nucleus
Cytosol Expressed in all testis: 33.2 -MARCH1 FLJ20668, MARCH-I, RNF171 ENSG00000145416 Membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 4 163524298-164384050 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA014600 Uncertain Supported Mitochondria Mixed lymph node: 36.5 -SFRP2 FRP-2, SARP1, SDF-5 ENSG00000145423 Secreted frizzled-related protein 2 4 153780592-153789120 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 gallbladder: 491.6;urinary bladder: 528.8 esophagus: 235.0 -RPS3A MFTL, S3A ENSG00000145425 Ribosomal protein S3A 4 151099573-151104652 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047100, HPA053454 Approved Validated Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 5244.0 -RNF175 FLJ34190 ENSG00000145428 Ring finger protein 175 4 153710125-153760235 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035837 Uncertain Tissue enhanced 0 cerebral cortex: 13.2 seminal vesicle: 4.8 -PDGFC fallotein, SCDGF ENSG00000145431 Platelet derived growth factor C 4 156760454-156971394 Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009134 Approved Supported Plasma membrane
Cytosol Tissue enhanced 0 parathyroid gland: 39.8 endometrium: 16.7 -CBR4 FLJ14431, SDR45C1 ENSG00000145439 Carbonyl reductase 4 4 168863770-169010275 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037499 Supported Expressed in all kidney: 28.6 -GLRA3 ENSG00000145451 Glycine receptor, alpha 3 4 174636914-174829314 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 6 breast: 2.6;cerebral cortex: 9.1 adrenal gland: 1.0 -CYP4V2 CYP4AH1 ENSG00000145476 Cytochrome P450, family 4, subfamily V, polypeptide 2 4 186191520-186213456 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029122 Approved Approved Nuclear speckles Tissue enhanced 0 parathyroid gland: 63.8 liver: 47.3 -ROPN1L ASP, FLJ25776, RSPH11 ENSG00000145491 Rhophilin associated tail protein 1-like 5 10441524-10472029 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039193, HPA041830 Supported Tissue enriched 7 testis: 297.9 fallopian tube: 42.9 -NDUFS6 CI-13kA ENSG00000145494 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 5 1801400-1816605 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064221 Supported Expressed in all skeletal muscle: 112.0 -MARCH6 MARCH-VI, RNF176, TEB4 ENSG00000145495 Membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 5 10353703-10440388 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040841, HPA063246 Approved Supported Endoplasmic reticulum Expressed in all parathyroid gland: 95.0 -NKD2 Naked2 ENSG00000145506 Naked cuticle homolog 2 (Drosophila) 5 1008829-1038943 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049463 Uncertain Tissue enhanced 0 lung: 5.6;skin: 3.8 spleen: 3.0 -CDH18 CDH14, EY-CADHERIN ENSG00000145526 Cadherin 18, type 2 5 19472951-20575873 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014416 Uncertain Tissue enhanced 0 adrenal gland: 5.9;cerebral cortex: 19.1 testis: 3.2 -ADAMTS16 ADAMTS16s ENSG00000145536 ADAM metallopeptidase with thrombospondin type 1 motif, 16 5 5140330-5320304 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 gallbladder: 10.0;ovary: 11.4 adipose tissue: 6.3 -SRD5A1 ENSG00000145545 Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 5 6633343-6674386 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051402 Approved Mixed skin: 17.1 -MYO10 KIAA0799 ENSG00000145555 Myosin X 5 16661914-16936276 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015224, HPA024223 Supported Supported Nucleoli
Plasma membrane
Cytosol Expressed in all cerebral cortex: 68.5 -FAM105A FLJ11127, NET20 ENSG00000145569 Family with sequence similarity 105, member A 5 14581775-14615007 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046638 Uncertain Approved Nucleoli
Cytosol Mixed bone marrow: 35.6 -RPL37 L37 ENSG00000145592 Ribosomal protein L37 5 40825262-40835335 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all breast: 920.6 -SKP2 FBL1, FBXL1, p45 ENSG00000145604 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 5 36151989-36184319 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013491, CAB013533, HPA051196, HPA054633 Approved Supported Nucleus
Cytosol Tissue enriched 6 placenta: 83.9 lymph node: 13.9 -OSMR OSMRB ENSG00000145623 Oncostatin M receptor 5 38845858-38945596 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017278 Approved Approved Nucleoli Mixed smooth muscle: 54.4 -UGT3A1 FLJ34658 ENSG00000145626 UDP glycosyltransferase 3 family, polypeptide A1 5 35951010-36001028 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047697, HPA056290 Uncertain Approved Vesicles
Cytosol Tissue enhanced 0 kidney: 52.9;liver: 29.1 duodenum: 9.7 -PLK2 SNK ENSG00000145632 Polo-like kinase 2 5 58453982-58460260 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB009624, HPA069329 Approved Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all spleen: 97.3 -FAM159B ENSG00000145642 Family with sequence similarity 159, member B 5 64690308-64718090 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA011778 Supported Group enriched 8 pancreas: 1.0;stomach: 3.5 duodenum: 0.2 -GZMA CTLA3, HFSP ENSG00000145649 Granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 5 55102648-55110252 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054134 Uncertain Mixed spleen: 72.0 -PIK3R1 GRB1, p85, p85-ALPHA ENSG00000145675 Phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5 68215720-68301821 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001216, CAB004268 Approved Approved Cytosol Expressed in all cerebral cortex: 133.3 -HAPLN1 CRTL1 ENSG00000145681 Hyaluronan and proteoglycan link protein 1 5 83637805-83721613 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019105, HPA019482 Supported Supported Vesicles Tissue enriched 8 placenta: 102.5 cerebral cortex: 12.8 -LHFPL2 KIAA0206 ENSG00000145685 Lipoma HMGIC fusion partner-like 2 5 78485215-78770021 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042402 Uncertain Approved Vesicles
Actin filaments Mixed gallbladder: 36.4 -SSBP2 HSPC116 ENSG00000145687 Single-stranded DNA binding protein 2 5 81413021-81751797 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB020834 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 84.2 -BHMT BHMT1 ENSG00000145692 Betaine--homocysteine S-methyltransferase 5 79111779-79132290 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038285, HPA058310 Supported Supported Cytosol Group enriched 216 kidney: 783.3;liver: 562.6 urinary bladder: 3.1 -ANKRD31 FLJ40191 ENSG00000145700 Ankyrin repeat domain 31 5 75068275-75236878 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA057566 Supported Tissue enriched 12 testis: 9.9 esophagus: 0.8 -IQGAP2 ENSG00000145703 IQ motif containing GTPase activating protein 2 5 76403249-76708132 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004241, HPA037403, HPA037404 Approved Approved Vesicles
Plasma membrane Tissue enhanced 0 parathyroid gland: 124.6 testis: 91.6 -CRHBP CRF-BP, CRFBP ENSG00000145708 Corticotropin releasing hormone binding protein 5 76952713-76981158 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046120 Approved Tissue enhanced 0 liver: 69.8;spleen: 42.8 kidney: 30.0 -RASA1 CM-AVM, GAP, p120GAP, p120RASGAP, RASA ENSG00000145715 RAS p21 protein activator (GTPase activating protein) 1 5 87267888-87391931 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007789, HPA036393, HPA064556 Supported Expressed in all placenta: 136.1 -LIX1 C5orf11, Lft ENSG00000145721 Limb and CNS expressed 1 5 97091867-97142872 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058426 Uncertain Tissue enriched 6 cerebral cortex: 32.9 seminal vesicle: 5.6 -GIN1 FLJ20125, GIN-1, TGIN1, ZH2C2 ENSG00000145723 Gypsy retrotransposon integrase 1 5 103086000-103120151 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037402, HPA061362 Approved Approved Nucleus
Nucleoli Mixed testis: 8.3 -PPIP5K2 CFAP160, HISPPD1, KIAA0433, VIP2 ENSG00000145725 Diphosphoinositol pentakisphosphate kinase 2 5 103120149-103212799 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037895, HPA038442 Approved Approved Vesicles Expressed in all parathyroid gland: 33.6 -PAM PAL, PHM ENSG00000145730 Peptidylglycine alpha-amidating monooxygenase 5 102753981-103031105 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026119, HPA042260 Supported Approved Golgi apparatus
Cytosol Expressed in all heart muscle: 1092.7 -BDP1 HSA238520, KIAA1241, KIAA1689, TAF3B1, TFC5, TFIIIB150, TFIIIB90, TFNR ENSG00000145734 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 5 71455615-71567820 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed thyroid gland: 1.6 -GTF2H2 BTF2, BTF2P44, p44, T-BTF2P44, TFIIH ENSG00000145736 General transcription factor IIH, polypeptide 2, 44kDa 5 71032670-71067689 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047001 Supported Nuclear speckles Mixed smooth muscle: 7.4 -SLC30A5 FLJ12496, FLJ12756, MGC5499, ZnT-5, ZNT5, ZNTL1, ZTL1 ENSG00000145740 Solute carrier family 30 (zinc transporter), member 5 5 69093646-69131069 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035373 Approved Supported Nucleus
Golgi apparatus Expressed in all thyroid gland: 61.6 -BTF3 BTF3a, BTF3b, NACB ENSG00000145741 Basic transcription factor 3 5 73498408-73505635 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013007, HPA056420 Approved Supported Cytosol Expressed in all ovary: 1439.3 -FBXL17 DKFZP434C1715, Fbl17, Fbx13, FBXO13 ENSG00000145743 F-box and leucine-rich repeat protein 17 5 107859035-108382098 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036410, HPA036411 Uncertain Approved Nucleus Expressed in all parathyroid gland: 43.5 -SPATA9 FLJ35906, NYD-SP16 ENSG00000145757 Spermatogenesis associated 9 5 95652181-95698711 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA010848 Uncertain Approved Mitochondria Tissue enriched 39 testis: 53.1 adipose tissue: 1.3 -TSLP ENSG00000145777 Thymic stromal lymphopoietin 5 111070062-111078024 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 gallbladder: 15.1 prostate: 10.1 -TNFAIP8 GG2-1, MDC-3.13, SCC-S2 ENSG00000145779 Tumor necrosis factor, alpha-induced protein 8 5 119268692-119399688 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054434, HPA057089 Uncertain Supported Nucleoplasm Expressed in all lymph node: 136.2 -FEM1C EUROIMAGE686608, EUROIMAGE783647, FEM1A, KIAA1785 ENSG00000145780 Fem-1 homolog c (C. elegans) 5 115520908-115544894 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059919, HPA060977 Approved Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 40.3 -COMMD10 PTD002 ENSG00000145781 COMM domain containing 10 5 116084991-116412762 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045441, HPA075641 Approved Uncertain Plasma membrane
Cytosol Expressed in all thyroid gland: 46.7 -ATG12 APG12, APG12L ENSG00000145782 Autophagy related 12 5 115828200-115841858 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013272 Uncertain Expressed in all cerebral cortex: 25.2 -MEGF10 KIAA1780 ENSG00000145794 Multiple EGF-like-domains 10 5 127290831-127465737 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 cerebral cortex: 15.8 adrenal gland: 2.2 -ADAMTS19 ENSG00000145808 ADAM metallopeptidase with thrombospondin type 1 motif, 19 5 129460265-129738683 Enzymes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056171, HPA058438 Uncertain Approved Vesicles
Midbody Group enriched 13 cervix, uterine: 16.4;endometrium: 16.4;placenta: 5.2;smooth muscle: 8.9 adrenal gland: 0.9 -YIPF5 FinGER5, SMAP-5 ENSG00000145817 Yip1 domain family, member 5 5 144158159-144170714 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042338, HPA073622 Supported Supported Nucleoplasm
Endoplasmic reticulum
Golgi apparatus
Vesicles Expressed in all placenta: 42.9 -ARHGAP26 GRAF, KIAA0621, OPHN1L, OPHN1L1 ENSG00000145819 Rho GTPase activating protein 26 5 142770384-143229011 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035106, HPA035107 Approved Approved Cytosol Mixed cerebral cortex: 30.9 -CXCL14 BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14 ENSG00000145824 Chemokine (C-X-C motif) ligand 14 5 135570679-135579279 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB029996 Uncertain Tissue enhanced 0 skin: 876.3 kidney: 333.5 -LECT2 chm-II, chm2 ENSG00000145826 Leukocyte cell-derived chemotaxin 2 5 135922279-135955034 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043883 Approved Tissue enriched 15 liver: 231.5 testis: 15.0 -SLC25A48 FLJ44862, HDMCP ENSG00000145832 Solute carrier family 25, member 48 5 135834649-135888637 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA014674 Uncertain Approved Intermediate filaments
Actin filaments Tissue enhanced 0 cerebral cortex: 17.7;kidney: 7.3 skeletal muscle: 2.7 -DDX46 FLJ25329, KIAA0801, Prp5, PRPF5 ENSG00000145833 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 5 134758771-134855133 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036554, HPA057501 Supported Validated Nuclear speckles Expressed in all parathyroid gland: 36.2 -IL9 HP40, IL-9, P40 ENSG00000145839 Interleukin 9 5 135892246-135895827 Cancer-related genes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 1.7 skin: 0.5 -TIMD4 ENSG00000145850 T-cell immunoglobulin and mucin domain containing 4 5 156919282-156963255 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015625, CAB026027 Approved Approved Plasma membrane
Cytosol Group enriched 6 lymph node: 64.4;testis: 161.6 adipose tissue: 17.7 -RNF145 FLJ31951 ENSG00000145860 Ring finger protein 145 5 159157409-159210053 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036562 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all lung: 109.1 -C1QTNF2 CTRP2 ENSG00000145861 C1q and tumor necrosis factor related protein 2 5 160347751-160370641 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061290 Approved Approved Golgi apparatus
Centrosome Mixed cervix: 4.5 -GABRA6 ENSG00000145863 Gamma-aminobutyric acid (GABA) A receptor, alpha 6 5 161547063-161702593 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA019188, CAB022462, HPA058329 Uncertain Tissue enhanced 0 testis: 1.2 cerebral cortex: 0.3 -GABRB2 ENSG00000145864 Gamma-aminobutyric acid (GABA) A receptor, beta 2 5 161288429-161549044 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001964, HPA067632 Supported Tissue enriched 11 cerebral cortex: 63.0 epididymis: 5.5 -FBXO38 Fbx38, FLJ13962, MOKA, SP329 ENSG00000145868 F-box protein 38 5 148383935-148442836 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034821, HPA041444 Approved Supported Nucleoplasm
Plasma membrane
Cytokinetic bridge
Cytosol Expressed in all parathyroid gland: 30.2 -SPINK7 ECG2, ECRG2 ENSG00000145879 Serine peptidase inhibitor, Kazal type 7 (putative) 5 148312419-148315922 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036294 Approved Group enriched 25 esophagus: 418.4;tonsil: 111.0 cervix: 10.4 -PCYOX1L MGC3265 ENSG00000145882 Prenylcysteine oxidase 1 like 5 149358007-149369653 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037463, HPA038402 Approved Approved Nucleoplasm
Mitochondria Tissue enhanced 0 parathyroid gland: 20.9 cerebral cortex: 12.5 -GLRA1 STHE ENSG00000145888 Glycine receptor, alpha 1 5 151822513-151924842 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level No evidence Evidence at protein level HPA016502 Uncertain Not detected adrenal gland: 0.4 -TNIP1 ABIN-1, KIAA0113, NAF1, VAN ENSG00000145901 TNFAIP3 interacting protein 1 5 151029945-151093577 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037893, HPA037894, HPA071950 Approved Supported Nucleoplasm
Cytosol Expressed in all adipose tissue: 132.2 -G3BP1 G3BP, HDH-VIII ENSG00000145907 GTPase activating protein (SH3 domain) binding protein 1 5 151771045-151812785 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004052, CAB037068 Supported Validated Cytosol Expressed in all testis: 90.7 -ZNF300 ENSG00000145908 Zinc finger protein 300 5 150894392-150904983 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028975, HPA051777 Uncertain Supported Nucleoplasm
Nucleoli Mixed ovary: 12.4 -N4BP3 LZTS4 ENSG00000145911 NEDD4 binding protein 3 5 178113443-178126087 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030972, HPA030973, HPA061387 Uncertain Supported Nucleoplasm
Centrosome Tissue enhanced 0 placenta: 11.8 parathyroid gland: 10.1 -NHP2 FLJ20479, NOLA2 ENSG00000145912 NHP2 ribonucleoprotein 5 178149460-178153967 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044171, HPA050400 Supported Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 115.1 -RMND5B FLJ22318, GID2, GID2B ENSG00000145916 Required for meiotic nuclear division 5 homolog B 5 178130996-178150565 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047778 Uncertain Approved Nucleoplasm Expressed in all testis: 94.4 -BOD1 FAM44B ENSG00000145919 Biorientation of chromosomes in cell division 1 5 173607514-173616660 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036293 Uncertain Expressed in all thyroid gland: 82.3 -CPLX2 CPX-2, DKFZp547D155 ENSG00000145920 Complexin 2 5 175796310-175884020 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA071191 Uncertain Vesicles Tissue enhanced 0 cerebral cortex: 237.1;epididymis: 143.5 adrenal gland: 44.6 -TENM2 KIAA1127, ODZ2, Ten-M2 ENSG00000145934 Teneurin transmembrane protein 2 5 167284799-168264157 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038018, HPA038420, HPA068691 Uncertain Approved Nucleoli Tissue enhanced 0 cerebral cortex: 9.2;heart muscle: 17.7 prostate: 3.4 -KCNMB1 hslo-beta ENSG00000145936 Potassium channel subfamily M regulatory beta subunit 1 5 170374671-170389677 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 seminal vesicle: 63.6;smooth muscle: 69.0 endometrium: 41.9 -FAM50B D6S2654E, X5L ENSG00000145945 Family with sequence similarity 50, member B 6 3849386-3851317 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064111, HPA067817 Approved Validated Nucleoplasm
Cytokinetic bridge Expressed in all cerebral cortex: 16.1 -MYLK4 SgK085 ENSG00000145949 Myosin light chain kinase family, member 4 6 2663629-2750966 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA015860 Uncertain Tissue enhanced 0 skeletal muscle: 9.8 kidney: 3.1 -FAM217A C6orf146, MGC43581 ENSG00000145975 Family with sequence similarity 217, member A 6 4049434-4087344 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035455 Uncertain Tissue enriched 128 testis: 20.9 pancreas: 0.1 -TBC1D7 dJ257A7.3, FLJ32666 ENSG00000145979 TBC1 domain family, member 7 6 13266542-13328583 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034748 Approved Expressed in all testis: 24.4 -FARS2 dJ236A3.1, FARS1 ENSG00000145982 Phenylalanyl-tRNA synthetase 2, mitochondrial 6 5261044-5771580 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018148, HPA028836 Approved Approved Plasma membrane Expressed in all thyroid gland: 24.3 -GFOD1 ADG-90, C6orf114, FLJ20330 ENSG00000145990 Glucose-fructose oxidoreductase domain containing 1 6 13357830-13487662 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029096 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Mixed cerebral cortex: 22.4 -CDKAL1 FLJ20342 ENSG00000145996 CDK5 regulatory subunit associated protein 1-like 1 6 20534457-21232404 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057474 Uncertain Vesicles Expressed in all thyroid gland: 15.9 -PSD2 DKFZp761B0514, EFA6C ENSG00000146005 Pleckstrin and Sec7 domain containing 2 5 139795821-139844466 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 29 cerebral cortex: 58.7 epididymis: 2.0 -LRRTM2 KIAA0416 ENSG00000146006 Leucine rich repeat transmembrane neuronal 2 5 138868923-138875368 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 10 cerebral cortex: 29.1 placenta: 3.0 -ZMAT2 FLJ31121, hSNU23, Snu23 ENSG00000146007 Zinc finger, matrin-type 2 5 140698680-140706676 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036518 Approved Approved Nucleus
Mitochondria Expressed in all cerebral cortex: 103.6 -GFRA3 GFRa-3 ENSG00000146013 GDNF family receptor alpha 3 5 138252379-138274671 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA020731 Approved Uncertain Plasma membrane
Cytosol Mixed seminal vesicle: 8.0 -KLHL3 KIAA1129 ENSG00000146021 Kelch-like family member 3 5 137617500-137736090 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051291 Approved Mixed thyroid gland: 13.7 -DCDC2 DCDC2A, KIAA1154, NPHP19, RU2 ENSG00000146038 Doublecortin domain containing 2 6 24171756-24358052 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031582, HPA031583, HPA031584 Supported Validated Nucleus
Cytosol Tissue enhanced 0 kidney: 23.0 parathyroid gland: 15.2 -SLC17A4 KIAA2138 ENSG00000146039 Solute carrier family 17, member 4 6 25754699-25781191 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055564 Approved Group enriched 6 colon: 20.8;duodenum: 29.4;gallbladder: 25.5;liver: 22.4;rectum: 29.4;small intestine: 35.7 pancreas: 4.2 -HIST1H2BA bA317E16.3, H2BFU, STBP, TSH2B ENSG00000146047 Histone cluster 1, H2ba 6 25726909-25727292 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011603, HPA042205, HPA043013 Supported Tissue enriched 65 testis: 17.2 kidney: 0.2 -KAAG1 RU2, RU2AS ENSG00000146049 Kidney associated antigen 1 6 24356903-24358284 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036021 Approved Not detected thyroid gland: 0.5 -TRIM7 GNIP, RNF90 ENSG00000146054 Tripartite motif containing 7 5 181193924-181205293 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039213 Approved Approved Nucleoplasm
Vesicles
Cytosol Group enriched 5 skeletal muscle: 67.7;skin: 22.2 esophagus: 8.7 -TRIM41 MGC1127, RINCK ENSG00000146063 Tripartite motif containing 41 5 181222499-181235809 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024204 Approved Supported Nucleoli
Nuclear bodies Expressed in all parathyroid gland: 21.5 -HIGD2A MGC2198 ENSG00000146066 HIG1 hypoxia inducible domain family, member 2A 5 176388747-176389771 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042715 Uncertain Supported Mitochondria
Cytosol Expressed in all parathyroid gland: 168.2 -FAM193B FLJ10404, KIAA1931 ENSG00000146067 Family with sequence similarity 193, member B 5 177519788-177554541 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035848, HPA058112 Approved Validated Nucleus
Nucleoli Expressed in all skin: 60.2 -PLA2G7 LDL-PLA2, PAFAH ENSG00000146070 Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 6 46704201-46735693 Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035916 Uncertain Vesicles Mixed spleen: 38.1 -TNFRSF21 CD358, DR6 ENSG00000146072 Tumor necrosis factor receptor superfamily, member 21 6 47231532-47309905 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006746, CAB009805 Approved Expressed in all parathyroid gland: 103.4 -RNF44 KIAA1100 ENSG00000146083 Ring finger protein 44 5 176526697-176538025 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA038981 Uncertain Approved Nucleoplasm Expressed in all spleen: 51.0 -MUT ENSG00000146085 Methylmalonyl CoA mutase 6 49430360-49463191 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035971, HPA035972 Supported Approved Mitochondria
Cytosol Expressed in all liver: 104.1 -RASGEF1C FLJ35841 ENSG00000146090 RasGEF domain family, member 1C 5 180100791-180209153 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028242 Uncertain Approved Mitochondria Group enriched 8 cerebral cortex: 16.5;testis: 6.1 seminal vesicle: 1.3 -DOK3 FLJ22570 ENSG00000146094 Docking protein 3 5 177501907-177511274 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 92.2 appendix: 65.2 -ABT1 ENSG00000146109 Activator of basal transcription 1 6 26596952-26600744 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all lymph node: 18.1 -PPP1R18 KIAA1949, phostensin ENSG00000146112 Protein phosphatase 1, regulatory subunit 18 6 30676389-30687895 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044745, HPA051000 Supported Approved Nucleoplasm
Plasma membrane Tissue enhanced 0 lymph node: 54.0 spleen: 35.7 -DAAM2 KIAA0381 ENSG00000146122 Dishevelled associated activator of morphogenesis 2 6 39792298-39904877 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051300, HPA054630 Approved Approved Nucleus
Cytosol Expressed in all cerebral cortex: 111.1 -PRIM2 PRIM2A ENSG00000146143 Primase, DNA, polypeptide 2 (58kDa) 6 57314805-57646849 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046566 Approved Nucleoplasm Tissue enhanced 0 prostate: 53.8 testis: 14.0 -MLIP C6orf142, MGC18257 ENSG00000146147 Muscular LMNA-interacting protein 6 53929982-54266280 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046654 Approved Nucleoplasm Tissue enhanced 0 heart muscle: 109.0;liver: 66.2;skeletal muscle: 45.7 skin: 20.6 -HMGCLL1 bA418P12.1, DKFZP434G1411 ENSG00000146151 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 6 55434369-55579214 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 14.6;placenta: 9.0 testis: 5.0 -LGSN GLULD1, LGS ENSG00000146166 Lengsin, lens protein with glutamine synthetase domain 6 63275951-63319977 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030957, HPA039983 Supported Approved Nucleoplasm
Vesicles Tissue enhanced 0 kidney: 2.8;liver: 2.4;placenta: 1.8 testis: 0.7 -FGD2 ZFYVE4 ENSG00000146192 FYVE, RhoGEF and PH domain containing 2 6 37005646-37029070 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029145, HPA049692 Approved Tissue enhanced 0 spleen: 43.1 lymph node: 25.3 -SCUBE3 CEGF3, FLJ34743 ENSG00000146197 Signal peptide, CUB domain, EGF-like 3 6 35214419-35253079 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040606 Uncertain Tissue enriched 7 thyroid gland: 49.2 seminal vesicle: 6.9 -ANO7 IPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G ENSG00000146205 Anoctamin 7 2 241188509-241225377 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035730 Uncertain Tissue enhanced 0 prostate: 86.9;stomach: 26.2 small intestine: 15.7 -CRIP3 bA480N24.2, TLP, TLP-A ENSG00000146215 Cysteine-rich protein 3 6 43299710-43308797 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA036198 Uncertain Approved Nuclear speckles Tissue enhanced 0 testis: 15.4 heart muscle: 13.0 -TTBK1 KIAA1855 ENSG00000146216 Tau tubulin kinase 1 6 43243680-43288259 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031735, HPA031736 Supported Supported Nucleoplasm
Cytosol Tissue enriched 6 cerebral cortex: 19.0 small intestine: 3.2 -TCTE1 D6S46, DRC5, FAP155, MGC33600 ENSG00000146221 T-complex-associated-testis-expressed 1 6 44278743-44297688 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA031739 Uncertain Uncertain Vesicles Group enriched 13 fallopian tube: 22.8;testis: 35.3 lung: 2.2 -RPL7L1 dJ475N16.4 ENSG00000146223 Ribosomal protein L7-like 1 6 42879618-42889925 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046049, HPA050478 Approved Nucleoli
Mitochondria Expressed in all parathyroid gland: 70.2 -NFKBIE IKBE ENSG00000146232 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 6 44258166-44265788 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002692, HPA005941, CAB010272 Supported Supported Nucleus
Nucleoli fibrillar center
Cytosol Mixed appendix: 26.8 -CYP39A1 ENSG00000146233 Cytochrome P450, family 39, subfamily A, polypeptide 1 6 46549580-46652830 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 liver: 56.7 epididymis: 28.4 -TPBG 5T4, 5T4-AG ENSG00000146242 Trophoblast glycoprotein 6 82363206-82370828 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010554 Supported Approved Nucleoplasm Mixed cervix: 17.4 -IRAK1BP1 AIP70, SIMPL ENSG00000146243 Interleukin-1 receptor-associated kinase 1 binding protein 1 6 78867472-78946440 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035742, HPA035743 Uncertain Approved Vesicles Tissue enriched 7 bone marrow: 60.0 epididymis: 8.4 -PHIP BRWD2, DCAF14, FLJ20705, ndrp, WDR11 ENSG00000146247 Pleckstrin homology domain interacting protein 6 78935867-79078236 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019140, HPA019838 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 21.9 -PRSS35 C6orf158, dJ223E3.1, MGC46520 ENSG00000146250 Protease, serine, 35 6 83512538-83525704 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038787, HPA038788 Uncertain Tissue enhanced 0 ovary: 12.9 cerebral cortex: 10.0 -MMS22L C6orf167, dJ39B17.2 ENSG00000146263 MMS22-like, DNA repair protein 6 97142161-97283217 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067042 Supported Nucleoplasm Tissue enhanced 0 testis: 12.3 bone marrow: 4.5 -FAXC C6orf168, dJ273F20, MGC2817 ENSG00000146267 Failed axon connections homolog 6 99271169-99350062 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039106 Uncertain Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 23.6 seminal vesicle: 14.7 -GABRR1 ENSG00000146276 Gamma-aminobutyric acid (GABA) A receptor, rho 1 6 89177501-89231278 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 6 testis: 1.8 placenta: 0.3 -PNRC1 B4-2, PROL2, PRR2 ENSG00000146278 Proline-rich nuclear receptor coactivator 1 6 89080751-89085160 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA029839, HPA066513 Approved Approved Nucleus
Nucleoli Expressed in all ovary: 271.2 -PM20D2 ACY1L2, bA63L7.3 ENSG00000146281 Peptidase M20 domain containing 2 6 89146050-89165565 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030325, HPA030326, HPA030327 Approved Validated Nucleoplasm Expressed in all prostate: 39.3 -RARS2 DALRD2, dJ382I10.6, MGC14993, MGC23778, PRO1992, RARSL ENSG00000146282 Arginyl-tRNA synthetase 2, mitochondrial 6 87514378-87590003 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039987, HPA042645 Uncertain Approved Nuclear bodies
Cytosol Expressed in all testis: 56.7 -SCML4 dJ47M23.1 ENSG00000146285 Sex comb on midleg-like 4 (Drosophila) 6 107704104-107824317 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063326, HPA065958 Approved Validated Nucleoplasm Tissue enhanced 0 lymph node: 16.3 spleen: 11.3 -TBC1D32 bA57L9.1, BROMI, C6orf170, C6orf171, dJ310J6.1, FLJ30899, FLJ34235 ENSG00000146350 TBC1 domain family, member 32 6 121079494-121334745 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA013413 Uncertain Approved Mitochondria Mixed testis: 6.0 -CLVS2 bA160A10.4, C6orf212, C6orf213, RLBP1L2 ENSG00000146352 Clavesin 2 6 122995971-123072927 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043764 Uncertain Group enriched 6 cerebral cortex: 15.5;prostate: 4.4 endometrium: 1.6 -GPR6 ENSG00000146360 G protein-coupled receptor 6 6 109978256-109980718 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 16 cerebral cortex: 1.5 epididymis: 0.0 -RNF217 C6orf172, dJ84N20.1, IBRDC1, MGC26996 ENSG00000146373 Ring finger protein 217 6 124962545-125092633 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029598 Uncertain Tissue enriched 8 parathyroid gland: 94.6 testis: 12.4 -RSPO3 FLJ14440, THSD2 ENSG00000146374 R-spondin 3 6 127118604-127197765 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029957 Approved Tissue enhanced 0 endometrium: 102.8;smooth muscle: 102.3 placenta: 72.8 -ARHGAP18 bA307O14.2, MacGAP ENSG00000146376 Rho GTPase activating protein 18 6 129576132-129710225 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031595 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Expressed in all adrenal gland: 48.2 -TAAR2 GPR58 ENSG00000146378 Trace amine associated receptor 2 6 132617022-132624275 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.4 -TAAR6 TA4, TRAR4 ENSG00000146383 Trace amine associated receptor 6 6 132570322-132571359 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected kidney: 0.1 -TAAR8 GPR102, TA5, TAR5, TRAR5 ENSG00000146385 Trace amine associated receptor 8 6 132552693-132553721 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -ABRACL C6orf115, Costars, HSPC280, PRO2013 ENSG00000146386 ABRA C-terminal like 6 139028682-139043302 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030217 Approved Approved Nucleoplasm
Cytosol Mixed epididymis: 145.3 -TAAR1 TA1, TAR1, TRAR1 ENSG00000146399 Trace amine associated receptor 1 6 132644984-132646003 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055614 Approved Group enriched 17 fallopian tube: 2.2;stomach: 7.9 prostate: 0.2 -SLC18B1 C6orf192, dJ55C23.6 ENSG00000146409 Solute carrier family 18, subfamily B, member 1 6 132769370-132798553 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029747, HPA049659 Approved Supported Golgi apparatus
Cytosol Expressed in all cerebral cortex: 37.6 -MTFR2 DUFD1, FAM54A ENSG00000146410 Mitochondrial fission regulator 2 6 136231024-136250335 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029792, HPA029794 Approved Uncertain Vesicles Tissue enhanced 0 testis: 12.7 bone marrow: 10.2 -SLC2A12 GLUT12, GLUT8 ENSG00000146411 Solute carrier family 2 (facilitated glucose transporter), member 12 6 133988697-134052636 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA031593, HPA031594 Approved Validated Plasma membrane
Cell Junctions Tissue enhanced 0 prostate: 38.8 endometrium: 15.7 -SHPRH bA545I5.2, FLJ90837, KIAA2023 ENSG00000146414 SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 6 145864245-145964423 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034854, HPA034950 Approved Approved Mitochondria Mixed ovary: 15.2 -AIG1 AIG-1, dJ95L4.1, FLJ10485 ENSG00000146416 Androgen-induced 1 6 143060496-143340304 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060766 Approved Approved Golgi apparatus Expressed in all liver: 153.9 -DYNLT1 TCTEL1 ENSG00000146425 Dynein, light chain, Tctex-type 1 6 158636474-158644739 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046559 Supported Nucleoplasm Expressed in all fallopian tube: 270.2 -TIAM2 STEF ENSG00000146426 T-cell lymphoma invasion and metastasis 2 6 154832697-155257723 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011134, HPA013903 Approved Supported Nucleoplasm
Nucleoli fibrillar center
Cytosol Tissue enhanced 0 cerebral cortex: 18.1;testis: 24.4 thyroid gland: 10.4 -TMEM181 GPR178, KIAA1423 ENSG00000146433 Transmembrane protein 181 6 158536436-158635428 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040189 Approved Approved Golgi apparatus
Vesicles Expressed in all cervix: 41.5 -PNLDC1 dJ195P10.2, FLJ40240 ENSG00000146453 Poly(A)-specific ribonuclease (PARN)-like domain containing 1 6 159800249-159820704 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052026 Uncertain Tissue enriched 5 testis: 12.2 fallopian tube: 2.3 -WTAP KIAA0105, MGC3925, Mum2 ENSG00000146457 Wilms tumor 1 associated protein 6 159725585-159756319 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010549, HPA010550 Supported Validated Nucleoplasm
Nuclear speckles Expressed in all bone marrow: 177.4 -ZMYM4 KIAA0425, MYM, ZNF198L3, ZNF262 ENSG00000146463 Zinc finger, MYM-type 4 1 35268967-35422058 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051301, HPA054802 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 63.6 -VIP ENSG00000146469 Vasoactive intestinal peptide 6 152750798-152759765 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017324, CAB018649, HPA072701 Supported Approved Endoplasmic reticulum Group enriched 5 appendix: 215.7;colon: 72.6;rectum: 69.1;small intestine: 53.7;smooth muscle: 57.4 duodenum: 17.3 -ARMT1 C6orf211, FLJ12910 ENSG00000146476 Acidic residue methyltransferase 1 6 151452258-151470101 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003004, HPA005819 Uncertain Approved Nucleus
Nuclear bodies
Cytosol Expressed in all thyroid gland: 42.5 -SLC22A3 EMT, OCT3 ENSG00000146477 Solute carrier family 22 (organic cation transporter), member 3 6 160348268-160452581 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029750 Approved Approved Nucleoplasm
Vesicles
Cytosol Mixed seminal vesicle: 70.0 -VWDE FLJ14712 ENSG00000146530 Von Willebrand factor D and EGF domains 7 12330885-12403941 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026619, HPA036044 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 thyroid gland: 3.9 heart muscle: 1.5 -GNA12 gep ENSG00000146535 Guanine nucleotide binding protein (G protein) alpha 12 7 2728112-2844324 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010046 Approved Approved Cytosol Expressed in all placenta: 34.4 -C7orf50 MGC11257, YCR016W ENSG00000146540 Chromosome 7 open reading frame 50 7 996986-1138260 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052281 Approved Approved Nucleus
Nucleoli Expressed in all cerebral cortex: 56.0 -SDK1 FLJ31425 ENSG00000146555 Sidekick cell adhesion molecule 1 7 3301448-4269000 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA011392 Approved Approved Cytosol Tissue enhanced 0 cervix, uterine: 14.9 spleen: 6.1 -CCZ1B C7orf28B, DKFZP586I1023, H_NH0577018.2, MGC19819 ENSG00000146574 CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated 7 6794134-6826770 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045114, HPA050006 Uncertain Validated Vesicles Expressed in all parathyroid gland: 48.7 -C7orf26 MGC2718 ENSG00000146576 Chromosome 7 open reading frame 26 7 6590017-6608726 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042899, HPA052175 Uncertain Approved Nucleus
Nucleoli
Intermediate filaments
Cytosol Expressed in all spleen: 26.2 -RBAK ZNF769 ENSG00000146587 RB-associated KRAB zinc finger 7 5045821-5069488 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071231 Supported Nucleoplasm Expressed in all parathyroid gland: 14.6 -CREB5 CRE-BPA, H_GS165L15.1 ENSG00000146592 CAMP responsive element binding protein 5 7 28299321-28825894 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050020, HPA061622 Approved Nucleus
Vesicles
Plasma membrane Mixed gallbladder: 18.6 -FERD3L bHLHa31, N-TWIST, NATO3 ENSG00000146618 Fer3-like bHLH transcription factor 7 19144782-19145421 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA043494 Uncertain Not detected cerebral cortex: 0.5 -EGFR ERBB, ERBB1 ENSG00000146648 Epidermal growth factor receptor 7 55019021-55256620 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000035, HPA001200, HPA018530, CAB068186, CAB073534 Supported Validated Plasma membrane Tissue enhanced 0 placenta: 97.3 skin: 58.9 -CDCA5 ENSG00000146670 Cell division cycle associated 5 11 65066300-65084164 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023691 Approved Supported Nucleoplasm Tissue enhanced 0 bone marrow: 31.0;testis: 46.4 lymph node: 19.2 -IGFBP3 BP-53, IBP3 ENSG00000146674 Insulin-like growth factor binding protein 3 7 45912245-45921874 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010360 Approved Nucleoplasm
Vesicles
Cytosol Tissue enhanced 0 placenta: 2649.6 endometrium: 881.5 -PURB PURBETA ENSG00000146676 Purine-rich element binding protein B 7 44876293-44885361 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048766 Supported Nucleus Expressed in all cerebral cortex: 24.6 -IGFBP1 AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12 ENSG00000146678 Insulin-like growth factor binding protein 1 7 45888357-45893668 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004445, HPA046972, HPA050640 Supported Approved Golgi apparatus Group enriched 53 endometrium: 120.4;liver: 562.2;placenta: 264.8 fallopian tube: 5.9 -SSC4D S4D-SRCRB, SRCRB-S4D, SRCRB4D ENSG00000146700 Scavenger receptor cysteine rich family, 4 domains 7 76389334-76409695 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062611 Uncertain Group enriched 5 kidney: 1.4;parathyroid gland: 4.1;thyroid gland: 2.0 cervix: 0.5 -MDH2 ENSG00000146701 Malate dehydrogenase 2, NAD (mitochondrial) 7 76048051-76067508 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019714, HPA019716, HPA019848, HPA026720 Supported Validated Mitochondria Expressed in all skeletal muscle: 233.3 -POMZP3 POM-ZP3, POM121 ENSG00000146707 POM121 and ZP3 fusion 7 76609986-76627261 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049817 Uncertain Approved Nucleoplasm
Nuclear membrane Mixed testis: 13.7 -GBAS NIPSNAP2 ENSG00000146729 Glioblastoma amplified sequence 7 55951793-56000181 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063084 Supported Supported Mitochondria Expressed in all skeletal muscle: 224.4 -CCT6A CCT6, Cctz, HTR3, TCP20, TCPZ, TTCP20 ENSG00000146731 Chaperonin containing TCP1, subunit 6A (zeta 1) 7 56051630-56063989 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042996, HPA045576, HPA049949 Supported Approved Cytosol Expressed in all parathyroid gland: 118.2 -PSPH PSP ENSG00000146733 Phosphoserine phosphatase 7 56011051-56051604 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020376, HPA029515 Approved Approved Cytosol Expressed in all fallopian tube: 25.2 -TRIM50 FLJ32804, TRIM50A ENSG00000146755 Tripartite motif containing 50 7 73312539-73328082 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA019862, HPA047843 Uncertain Approved Cytosol Tissue enhanced 0 stomach: 10.1;testis: 4.6 kidney: 1.7 -ZNF92 HPF12, TF12 ENSG00000146757 Zinc finger protein 92 7 65373799-65401135 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003173 Approved Nucleus Mixed breast: 13.1 -ATXN7L1 ATXN7L4, KIAA1218, MGC33190 ENSG00000146776 Ataxin 7-like 1 7 105605067-105876604 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA021448 Approved Approved Nucleus
Cytosol Mixed testis: 16.4 -TMEM168 DKFZp564C012, FLJ13576 ENSG00000146802 Transmembrane protein 168 7 112762382-112790592 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA020389 Approved Expressed in all parathyroid gland: 43.5 -ASB15 FLJ43370 ENSG00000146809 Ankyrin repeat and SOCS box containing 15 7 123567010-123639481 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 heart muscle: 19.6;skeletal muscle: 43.9 kidney: 7.4 -C7orf43 FLJ10925 ENSG00000146826 Chromosome 7 open reading frame 43 7 100154420-100158715 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019359, HPA029463, HPA029464 Approved Validated Vesicles
Plasma membrane
Microtubule organizing center Expressed in all testis: 33.4 -SLC12A9 CIP1 ENSG00000146828 Solute carrier family 12, member 9 7 100826820-100867009 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed placenta: 20.0 -GIGYF1 GYF1, PERQ1 ENSG00000146830 GRB10 interacting GYF protein 1 7 100679507-100689448 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020999, HPA023995 Approved Approved Vesicles
Microtubules Expressed in all endometrium: 35.7 -TRIM4 RNF87 ENSG00000146833 Tripartite motif containing 4 7 99876958-99919600 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019356, HPA029461 Approved Supported Plasma membrane
Cytosol Expressed in all ovary: 50.7 -MEPCE BCDIN3, FLJ20257, MePCE ENSG00000146834 Methylphosphate capping enzyme 7 100428790-100434126 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026384, HPA051587 Supported Approved Nucleoplasm
Cell Junctions Expressed in all testis: 87.7 -ZAN ENSG00000146839 Zonadhesin (gene/pseudogene) 7 100733626-100797797 Predicted membrane proteins No evidence No evidence Not detected testis: 0.5 -TMEM209 FLJ14803, NET31 ENSG00000146842 Transmembrane protein 209 7 130164715-130207770 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031678 Uncertain Approved Nuclear membrane
Nuclear speckles
Vesicles Expressed in all testis: 27.7 -AGBL3 CCP3, MGC32955 ENSG00000146856 ATP/GTP binding protein-like 3 7 134986508-135147963 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA020397, HPA024150 Uncertain Uncertain Nuclear speckles
Mitochondria
Cytosol Mixed testis: 9.3 -STRA8 ENSG00000146857 Stimulated by retinoic acid 8 7 135231979-135258492 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 1.7 skin: 0.7 -ZC3HAV1L C7orf39, MGC14289 ENSG00000146858 Zinc finger CCCH-type, antiviral 1-like 7 139025706-139036029 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020386, HPA050741 Uncertain Validated Cytosol Mixed thyroid gland: 14.4 -TMEM140 FLJ11000 ENSG00000146859 Transmembrane protein 140 7 135148072-135166215 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all spleen: 40.1 -TLK2 MGC44450, PKU-ALPHA ENSG00000146872 Tousled-like kinase 2 17 62458658-62615481 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 104.1 -EPHA1 EPH, EPHT, EPHT1 ENSG00000146904 EPH receptor A1 7 143390289-143408892 Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026144 Approved Tissue enriched 24 parathyroid gland: 861.4 esophagus: 36.4 -NOM1 C7orf3, PPP1R113, SGD1 ENSG00000146909 Nucleolar protein with MIF4G domain 1 7 156949723-156973182 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019866, HPA051624 Approved Validated Nucleoli Mixed testis: 7.5 -CNPY1 ENSG00000146910 Canopy FGF signaling regulator 1 7 155474206-155533862 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA047400 Uncertain Group enriched 7 pancreas: 1.2;testis: 1.9 cervix: 0.2 -NCAPG2 CAP-G2, FLJ20311, hCAP-G2, LUZP5, MTB ENSG00000146918 Non-SMC condensin II complex, subunit G2 7 158631311-158704829 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026631 Approved Supported Nuclear speckles Mixed testis: 27.6 -ASB10 GLC1F ENSG00000146926 Ankyrin repeat and SOCS box containing 10 7 151175698-151187832 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 8 skeletal muscle: 27.9 heart muscle: 3.5 -NLGN4X HLNX, KIAA1260, NLGN, NLGN4 ENSG00000146938 Neuroligin 4, X-linked X 5840637-6228863 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001651 Approved Tissue enhanced 0 cerebral cortex: 20.2 ovary: 12.9 -SHROOM2 APXL ENSG00000146950 Shroom family member 2 X 9786456-9949443 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051646 Approved Approved Plasma membrane
Cell Junctions
Cytosol Mixed cerebral cortex: 11.8 -RAB19 RAB19B ENSG00000146955 RAB19, member RAS oncogene family 7 140404043-140426250 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051077 Uncertain Mixed parathyroid gland: 6.1 -LUC7L2 CGI-59, CGI-74, FLJ10657, hLuc7B2, H_NH0792N18.3, LUC7B2 ENSG00000146963 LUC7-like 2 pre-mRNA splicing factor 7 139340359-139423457 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051631 Approved Approved Nucleus Expressed in all thyroid gland: 100.3 -DENND2A FAM31D, KIAA1277 ENSG00000146966 DENN/MADD domain containing 2A 7 140518420-140673993 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA021778, HPA026718 Approved Mixed endometrium: 31.8 -TMEM27 NX17 ENSG00000147003 Transmembrane protein 27 X 15627318-15665031 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048543 Approved Approved Endoplasmic reticulum
Vesicles Tissue enriched 16 kidney: 418.5 parathyroid gland: 26.1 -SH3KBP1 CIN85 ENSG00000147010 SH3-domain kinase binding protein 1 X 19533975-19887601 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003351, HPA003355, CAB021892 Supported Supported Cytosol Expressed in all lymph node: 80.5 -TMEM47 BCMP1, DKFZp564E153, DKFZP761J17121, TM4SF10 ENSG00000147027 Transmembrane protein 47 X 34627064-34657288 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046658 Approved Approved Nuclear membrane Mixed endometrium: 74.9 -LANCL3 FLJ42925 ENSG00000147036 LanC lantibiotic synthetase component C-like 3 (bacterial) X 37571569-37684463 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA005470 Approved Mixed esophagus: 1.4 -SYTL5 ENSG00000147041 Synaptotagmin-like 5 X 38006582-38128819 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026074 Uncertain Approved Nucleoplasm
Microtubules
Cytosol Tissue enhanced 0 stomach: 11.8 placenta: 10.5 -CASK CAGH39, FGS4, LIN2, TNRC8 ENSG00000147044 Calcium/calmodulin-dependent serine protein kinase (MAGUK family) X 41514934-41923463 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001949, HPA023857 Supported Approved Nucleoplasm
Cytosol Expressed in all small intestine: 35.2 -KDM6A UTX ENSG00000147050 Lysine (K)-specific demethylase 6A X 44873177-45112602 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000568, HPA001165, HPA002111 Supported Approved Nucleoli Expressed in all bone marrow: 41.1 -SPIN2A DXF34, SPIN2, TDRD25 ENSG00000147059 Spindlin family, member 2A X 57134530-57137625 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA000162, HPA069835 Uncertain Approved Nucleoplasm Mixed cerebral cortex: 1.6 -MSN ENSG00000147065 Moesin X 65588377-65741931 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047338 Supported Validated Plasma membrane Expressed in all lung: 421.4 -AKAP4 AKAP82, CT99, Fsc1, hAKAP82, HI, p82 ENSG00000147081 A kinase (PRKA) anchor protein 4 X 50190768-50201013 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005949, HPA020046 Supported Tissue enriched 2780 testis: 278.0 epididymis: 0.0 -CCNB3 ENSG00000147082 Cyclin B3 X 50202713-50351910 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000496 Approved Supported Nuclear speckles Group enriched 9 epididymis: 5.8;testis: 7.9 cerebral cortex: 0.7 -HDAC8 HDACL1, MRXS6, RPD3, WTS ENSG00000147099 Histone deacetylase 8 X 72329516-72573103 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048560 Supported Supported Nucleus
Plasma membrane Expressed in all epididymis: 26.9 -SLC16A2 AHDS, DXS128, MCT7, MCT8, MRX22, XPCT ENSG00000147100 Solute carrier family 16, member 2 (thyroid hormone transporter) X 74421461-74533917 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072719 Approved Plasma membrane Mixed liver: 41.9 -CXorf36 DIA1R, FLJ14103 ENSG00000147113 Chromosome X open reading frame 36 X 45148374-45200901 Disease related genes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA002806 Uncertain Tissue enhanced 0 placenta: 58.0 adipose tissue: 36.2 -ZNF157 HZF22 ENSG00000147117 Zinc finger protein 157 X 47370583-47414305 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003319 Uncertain Mixed fallopian tube: 2.1 -ZNF182 HHZ150, KOX14, Zfp182, ZNF21 ENSG00000147118 Zinc finger protein 182 X 47974851-48003978 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059574 Uncertain Approved Nucleus Mixed thyroid gland: 9.5 -CHST7 C6ST-2, C6ST2 ENSG00000147119 Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 X 46573784-46598408 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003919 Approved Mixed spleen: 13.0 -KRBOX4 FLJ20344, ZNF673 ENSG00000147121 KRAB box domain containing 4 X 46446857-46497422 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA065295 Approved Nucleoplasm Expressed in all endometrium: 29.3 -NDUFB11 ESSS, Np15, NP17.3 ENSG00000147123 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa X 47142216-47145504 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030367 Supported Validated Mitochondria Expressed in all skeletal muscle: 129.1 -ZNF41 MGC8941, MRX89 ENSG00000147124 Zinc finger protein 41 X 47445879-47482946 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA069102 Supported Approved Nucleoplasm Mixed parathyroid gland: 19.1 -RAB41 ENSG00000147127 RAB41, member RAS oncogene family X 70282093-70285002 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001510 Uncertain Tissue enhanced 0 testis: 7.2 cerebral cortex: 5.0 -ZMYM3 DXS6673E, KIAA0385, MYM, ZNF198L2, ZNF261 ENSG00000147130 Zinc finger, MYM-type 3 X 71239624-71255146 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003211 Approved Approved Nucleoplasm Expressed in all ovary: 43.8 -TAF1 BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250 ENSG00000147133 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa X 71366239-71532374 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001075, CAB016283 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 25.7 -GPR174 FKSG79 ENSG00000147138 G protein-coupled receptor 174 X 79170972-79172229 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA041025 Supported Uncertain Vesicles Tissue enhanced 0 lymph node: 30.2;spleen: 16.9;tonsil: 17.8 appendix: 13.1 -NONO NMT55, NRB54, P54, P54NRB, PPP1R114 ENSG00000147140 Non-POU domain containing, octamer-binding X 71283192-71301168 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022069, HPA054094, HPA054559 Supported Validated Nucleoplasm Expressed in all ovary: 245.1 -CCDC120 JM11 ENSG00000147144 Coiled-coil domain containing 120 X 49053572-49069857 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000561 Approved Uncertain Mitochondria Mixed skin: 17.9 -LPAR4 GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9 ENSG00000147145 Lysophosphatidic acid receptor 4 X 78747709-78757094 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA054951, HPA055571 Uncertain Tissue enhanced 0 ovary: 4.5 cerebral cortex: 2.2 -EBP CDPX2, CHO2, CPX, CPXD ENSG00000147155 Emopamil binding protein (sterol isomerase) X 48521158-48528716 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003130 Approved Supported Endoplasmic reticulum Expressed in all liver: 91.1 -AWAT2 DGAT2L4, MFAT ENSG00000147160 Acyl-CoA wax alcohol acyltransferase 2 X 70040542-70049938 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062748 Approved Tissue enhanced 0 breast: 2.0;skin: 1.2 testis: 0.5 -OGT FLJ23071, HRNT1, MGC22921, O-GLCNAC ENSG00000147162 O-linked N-acetylglucosamine (GlcNAc) transferase X 71533083-71575897 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030751, HPA030752, HPA030753, HPA030754, CAB034099 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all spleen: 84.4 -SNX12 ENSG00000147164 Sorting nexin 12 X 71056332-71073426 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB070423 Approved Expressed in all parathyroid gland: 58.0 -ITGB1BP2 CHORDC3 ENSG00000147166 Integrin beta 1 binding protein (melusin) 2 X 71301734-71305371 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040721 Approved Cytosol Tissue enhanced 0 heart muscle: 57.8 smooth muscle: 22.8 -IL2RG CD132, CIDX, IMD4, SCIDX1 ENSG00000147168 Interleukin 2 receptor, gamma X 71107404-71112108 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046641, HPA049691 Supported Approved Vesicles Tissue enhanced 0 lymph node: 277.4;tonsil: 290.2 appendix: 188.7 -ACRC ENSG00000147174 Acidic repeat containing X 71578411-71613583 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023476 Supported Approved Vesicles Group enriched 5 adrenal gland: 5.9;testis: 20.6 spleen: 2.5 -ZNF711 CMPX1, dJ75N13.1, MRX97, Zfp711, ZNF4, ZNF5, ZNF6 ENSG00000147180 Zinc finger protein 711 X 85244032-85273362 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030654 Supported Approved Nucleoplasm Tissue enhanced 0 testis: 69.6 cerebral cortex: 32.8 -CPXCR1 CT77 ENSG00000147183 CPX chromosome region, candidate 1 X 88747225-88754785 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 57 testis: 11.4 fallopian tube: 0.2 -DIAPH2 DIA, DIA2, POF, POF2 ENSG00000147202 Diaphanous-related formin 2 X 96684663-97604997 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005647, CAB015461, CAB068183, CAB068184 Supported Supported Nucleoli
Endoplasmic reticulum
Vesicles Expressed in all placenta: 17.6 -NXF3 ENSG00000147206 Nuclear RNA export factor 3 X 103075810-103093125 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003132, HPA046757 Approved Supported Nucleoplasm Tissue enhanced 0 fallopian tube: 39.4;testis: 71.6 epididymis: 13.3 -RIPPLY1 ENSG00000147223 Ripply transcriptional repressor 1 X 106900063-106903335 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052284 Uncertain Tissue enhanced 0 kidney: 2.3;liver: 3.2 seminal vesicle: 1.3 -PRPS1 CMTX5, DFN2, DFNX1 ENSG00000147224 Phosphoribosyl pyrophosphate synthetase 1 X 107628424-107651026 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043760 Uncertain Approved Cytosol Expressed in all thyroid gland: 73.6 -CXorf57 FLJ10178, FLJ14191 ENSG00000147231 Chromosome X open reading frame 57 X 106611930-106679442 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000896, HPA001374 Uncertain Approved Intermediate filaments Mixed adrenal gland: 9.5 -FRMPD3 KIAA1817, RP5-1070B1.1 ENSG00000147234 FERM and PDZ domain containing 3 X 107522450-107605251 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003164 Uncertain Tissue enhanced 0 cerebral cortex: 5.9;ovary: 6.7;thyroid gland: 5.5 seminal vesicle: 1.9 -HTR2C 5-HT2C, 5HTR2C, HTR1C ENSG00000147246 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled X 114584078-114910061 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 5 cerebral cortex: 3.1 cervix: 0.5 -DOCK11 ACG, FLJ32122, FLJ43653, ZIZ2 ENSG00000147251 Dedicator of cytokinesis 11 X 118495898-118686163 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059695 Uncertain Approved Nuclear membrane
Nucleoli Mixed adipose tissue: 33.9 -IGSF1 IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2 ENSG00000147255 Immunoglobulin superfamily, member 1 X 131273506-131578899 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035582 Supported Approved Cytosol Tissue enhanced 0 testis: 19.9 adrenal gland: 13.2 -ARHGAP36 FLJ30058 ENSG00000147256 Rho GTPase activating protein 36 X 131058242-131089883 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA002064 Supported Approved Nucleus
Vesicles
Plasma membrane Tissue enriched 19 adrenal gland: 138.4 cerebral cortex: 7.4 -GPC3 DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1 ENSG00000147257 Glypican 3 X 133535745-133985895 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006316 Approved Plasma membrane Tissue enriched 6 placenta: 838.1 lung: 130.8 -GPR119 GPCR2, hGPCR2 ENSG00000147262 G protein-coupled receptor 119 X 130384440-130385447 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Not detected pancreas: 0.6 -RBMX hnRNP-G, HNRNPG, RNMX ENSG00000147274 RNA binding motif protein, X-linked X 136848004-136880764 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057707 Supported Approved Nucleoplasm Expressed in all ovary: 296.1 -MCPH1 BRIT1, FLJ12847 ENSG00000147316 Microcephalin 1 8 6406592-6648504 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008238, CAB012177 Supported Uncertain Nucleoplasm
Nuclear bodies Expressed in all testis: 19.4 -MFHAS1 LRRC65, MASL1 ENSG00000147324 Malignant fibrous histiocytoma amplified sequence 1 8 8783354-8893645 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051213, HPA054471 Uncertain Approved Nucleoplasm
Cytosol Mixed spleen: 16.9 -FBXO25 FBX25 ENSG00000147364 F-box protein 25 8 406428-477967 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 150.6 -FATE1 CT43, FATE ENSG00000147378 Fetal and adult testis expressed 1 X 151716035-151723194 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034604 Supported Tissue enriched 313 testis: 307.8 cerebral cortex: 0.9 -MAGEA4 CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336 ENSG00000147381 Melanoma antigen family A4 X 151912509-151925170 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021942, CAB040535 Supported Approved Nuclear speckles
Cytosol Tissue enriched 7 testis: 44.8 placenta: 6.6 -NSDHL H105e3, SDR31E1, XAP104 ENSG00000147383 NAD(P) dependent steroid dehydrogenase-like X 152830967-152869729 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000248, HPA000571 Supported Validated Endoplasmic reticulum
Lipid droplets Expressed in all epididymis: 53.2 -ZNF185 ENSG00000147394 Zinc finger protein 185 (LIM domain) X 152914442-152973480 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000400, HPA016438 Supported Supported Plasma membrane
Actin filaments
Focal adhesion sites
Cytosol Tissue enhanced 0 epididymis: 393.3;esophagus: 279.4;seminal vesicle: 200.0 cervix: 104.7 -CETN2 CALT, CEN2 ENSG00000147400 Centrin, EF-hand protein, 2 X 152826973-152830777 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028956 Uncertain Expressed in all fallopian tube: 371.0 -RPL10 DXS648, DXS648E, FLJ23544, L10, NOV, QM ENSG00000147403 Ribosomal protein L10 X 154389955-154409168 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010339, HPA011311 Supported Validated Endoplasmic reticulum
Cytosol Expressed in all ovary: 9655.2 -CSGALNACT1 ChGn, CSGalNAcT-1, FLJ11264 ENSG00000147408 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 8 19404161-19758029 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061336 Supported Actin filaments Expressed in all thyroid gland: 144.8 -ATP6V1B2 ATP6B2, HO57, VATB, Vma2, VPP3 ENSG00000147416 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 8 20197367-20226819 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008147 Supported Supported Vesicles Expressed in all cerebral cortex: 305.1 -CCDC25 FLJ10853 ENSG00000147419 Coiled-coil domain containing 25 8 27733311-27772653 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023256 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all duodenum: 36.6 -HMBOX1 FLJ21616, HNF1LA, HOT1, PBHNF ENSG00000147421 Homeobox containing 1 8 28890394-29064764 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055855, HPA058586, CAB070418 Approved Validated Nucleoplasm
Nuclear bodies
Cytosol Mixed testis: 14.0 -CHRNB3 ENSG00000147432 Cholinergic receptor, nicotinic, beta 3 (neuronal) 8 42697376-42737407 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045555 Uncertain Tissue enriched 6 testis: 3.7 cerebral cortex: 0.6 -CHRNA6 ENSG00000147434 Cholinergic receptor, nicotinic, alpha 6 (neuronal) 8 42752620-42796392 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected fallopian tube: 0.6 -GNRH1 GNRH, GRH, LHRH ENSG00000147437 Gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 8 25419260-25424654 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA027532 Approved Mixed skin: 10.4 -BIN3 ENSG00000147439 Bridging integrator 3 8 22620418-22669148 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023769 Approved Mixed bone marrow: 25.6 -DOK2 Dok-2, p56dok-2 ENSG00000147443 Docking protein 2, 56kDa 8 21908873-21913860 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004379 Supported Mixed spleen: 35.6 -SLC25A37 MFRN, MFRN1, MSCP ENSG00000147454 Solute carrier family 25 (mitochondrial iron transporter), member 37 8 23528805-23575463 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045680 Uncertain Expressed in all bone marrow: 80.2 -CHMP7 MGC29816 ENSG00000147457 Charged multivesicular body protein 7 8 23243637-23262000 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036119 Uncertain Supported Nucleus
Cytosol Tissue enhanced 0 lymph node: 39.0 tonsil: 26.4 -DOCK5 FLJ21034 ENSG00000147459 Dedicator of cytokinesis 5 8 25184723-25418082 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017719, HPA056837 Approved Validated Cytosol Mixed spleen: 18.9 -STAR StAR, STARD1 ENSG00000147465 Steroidogenic acute regulatory protein 8 38143649-38151265 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023644, HPA027318, CAB032598 Supported Tissue enriched 12 adrenal gland: 2892.5 ovary: 245.1 -PROSC ENSG00000147471 Proline synthetase co-transcribed homolog (bacterial) 8 37762593-37779767 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017033, HPA023646, HPA023733 Approved Approved Cytosol Expressed in all parathyroid gland: 58.4 -ERLIN2 C8orf2, Erlin-2, NET32, SPFH2, SPG18 ENSG00000147475 ER lipid raft associated 2 8 37736599-37759101 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002025, CAB014894 Supported Supported Endoplasmic reticulum Expressed in all thyroid gland: 80.6 -SNTG1 G1SYN, SYN4 ENSG00000147481 Syntrophin, gamma 1 8 49909789-50794118 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA072282 Supported Tissue enhanced 0 cerebral cortex: 8.6;spleen: 3.9 testis: 1.2 -PXDNL FLJ25471, PMR1 ENSG00000147485 Peroxidasin-like 8 51319578-51809445 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007919 Approved Nucleoplasm
Cytosol Group enriched 8 epididymis: 11.3;heart muscle: 24.9;testis: 9.0 adipose tissue: 1.8 -ST18 KIAA0535, NZF3, ZC2HC10, ZNF387 ENSG00000147488 Suppression of tumorigenicity 18, zinc finger 8 52110839-52460959 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044919 Uncertain Tissue enriched 7 cerebral cortex: 11.6 stomach: 1.5 -RGS20 RGSZ1, ZGAP1 ENSG00000147509 Regulator of G-protein signaling 20 8 53851808-53959303 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 10.2 thyroid gland: 2.1 -TACC1 ENSG00000147526 Transforming, acidic coiled-coil containing protein 1 8 38728186-38853028 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017041, HPA024702 Approved Approved Intermediate filaments
Microtubules Expressed in all adipose tissue: 166.0 -GOLGA7 GCP16, GOLGA3AP1, GOLGA7A, HSPC041 ENSG00000147533 Golgin A7 8 41490396-41510980 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046878 Uncertain Expressed in all cerebral cortex: 96.7 -PLPP5 DPPL1, HTPAP, PPAPDC1B ENSG00000147535 Phospholipid phosphatase 5 8 38263130-38269243 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055777 Approved Vesicles Expressed in all prostate: 123.7 -GINS4 MGC14799, SLD5 ENSG00000147536 GINS complex subunit 4 (Sld5 homolog) 8 41529206-41545046 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024663, HPA026580 Uncertain Supported Nucleoplasm
Centrosome Mixed lymph node: 6.3 -WHSC1L1 FLJ20353, NSD3 ENSG00000147548 Wolf-Hirschhorn syndrome candidate 1-like 1 8 38269697-38382272 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005659, CAB013721, HPA018893 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all placenta: 47.5 -DNAJC5B CSP-beta, MGC26226 ENSG00000147570 DnaJ (Hsp40) homolog, subfamily C, member 5 beta 8 66021560-66100526 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 12 testis: 113.3 lung: 9.2 -CRH CRF, CRH1 ENSG00000147571 Corticotropin releasing hormone 8 66176382-66178725 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010885, HPA046846, HPA062111 Uncertain Supported Tissue enhanced 0 cerebral cortex: 2.1;placenta: 8.0 adipose tissue: 1.2 -TRIM55 MURF-2, RNF29 ENSG00000147573 Tripartite motif containing 55 8 66126896-66175487 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038793, HPA053691 Approved Approved Golgi apparatus
Cytosol Tissue enhanced 0 heart muscle: 41.4;liver: 19.8 testis: 13.1 -ADHFE1 ADHFe1, FLJ32430 ENSG00000147576 Alcohol dehydrogenase, iron containing, 1 8 66430185-66471601 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023062 Approved Approved Vesicles Mixed liver: 14.3 -MRPS28 HSPC007, MRP-S28, MRPS35 ENSG00000147586 Mitochondrial ribosomal protein S28 8 79918717-80030289 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027202 Approved Validated Mitochondria Expressed in all adrenal gland: 114.6 -PMP2 FABP8, M-FABP, MP2 ENSG00000147588 Peripheral myelin protein 2 8 81440326-81447523 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 55 cerebral cortex: 289.4 seminal vesicle: 5.2 -LACTB2 CGI-83 ENSG00000147592 Lactamase, beta 2 8 70635318-70669174 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044391, HPA053040 Approved Supported Nucleus
Golgi apparatus
Cytosol Expressed in all testis: 118.9 -PRDM14 ENSG00000147596 PR domain containing 14 8 70051651-70071693 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019094, HPA057070 Uncertain Uncertain Nucleoplasm Tissue enhanced 0 testis: 1.8 epididymis: 0.5 -TERF1 PIN2, TRBF1, TRF, TRF1 ENSG00000147601 Telomeric repeat binding factor (NIMA-interacting) 1 8 73008864-73048122 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048379 Supported Nucleoli fibrillar center
Nuclear bodies Expressed in all cerebral cortex: 45.9 -RPL7 humL7-1, L7 ENSG00000147604 Ribosomal protein L7 8 73290267-73295789 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058373 Approved Approved Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 5517.3 -SLC26A7 SUT2 ENSG00000147606 Solute carrier family 26 (anion exchanger), member 7 8 91209494-91398152 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 21 thyroid gland: 548.4 kidney: 26.1 -PSKH2 ENSG00000147613 Protein serine kinase H2 8 86048373-86088621 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015095 Uncertain Not detected testis: 0.4 -ATP6V0D2 ATP6D2, FLJ38708, VMA6 ENSG00000147614 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 8 85987323-86154228 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055327, HPA058496 Supported Approved Vesicles Tissue enriched 15 kidney: 59.1 lung: 3.8 -SYBU FLJ20366, GOLSYN, KIAA1472, OCSYN, SNPHL ENSG00000147642 Syntabulin (syntaxin-interacting) 8 109573978-109691791 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053057 Uncertain Supported Vesicles Tissue enhanced 0 cerebral cortex: 76.3 adrenal gland: 40.8 -DPYS DHPase ENSG00000147647 Dihydropyrimidinase 8 104330324-104467053 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024785 Supported Group enriched 22 kidney: 199.0;liver: 245.6 gallbladder: 10.2 -MTDH 3D3, AEG-1, LYRIC ENSG00000147649 Metadherin 8 97644179-97728770 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010932, HPA015104, CAB068204, CAB068205 Supported Validated Endoplasmic reticulum Expressed in all thyroid gland: 104.0 -LRP12 FLJ12929, ST7 ENSG00000147650 Low density lipoprotein receptor-related protein 12 8 104489231-104589024 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017245 Uncertain Approved Nucleoli fibrillar center
Plasma membrane
Mitochondria Mixed endometrium: 27.6 -EBAG9 EB9, RCAS1 ENSG00000147654 Estrogen receptor binding site associated, antigen, 9 8 109539711-109565996 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021153, HPA021154, CAB072810, CAB072811, CAB072812 Supported Validated Golgi apparatus Expressed in all thyroid gland: 96.1 -RSPO2 MGC35555 ENSG00000147655 R-spondin 2 8 107899316-108083648 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA024764, CAB025900, HPA053068 Approved Tissue enhanced 0 cerebral cortex: 20.3;placenta: 25.6 prostate: 14.7 -POLR2K RPB10alpha ENSG00000147669 Polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 8 100150584-100154002 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA063185 Approved Nucleus
Nucleoli
Cytosol Expressed in all thyroid gland: 98.0 -MAL2 ENSG00000147676 Mal, T-cell differentiation protein 2 (gene/pseudogene) 8 119165034-119245673 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043831 Uncertain Mixed esophagus: 267.5 -EIF3H eIF3-gamma, eIF3-p40, eIF3h, EIF3S3 ENSG00000147677 Eukaryotic translation initiation factor 3, subunit H 8 116642130-116766925 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023117, HPA023553 Approved Approved Cytosol Expressed in all ovary: 479.7 -UTP23 C8orf53, MGC14595 ENSG00000147679 UTP23, small subunit (SSU) processome component, homolog (yeast) 8 116766503-116849463 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044418 Uncertain Approved Nucleoli Expressed in all bone marrow: 21.3 -NDUFB9 B22, LYRM3, UQOR22 ENSG00000147684 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 8 124539103-124568510 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042768 Approved Supported Mitochondria Expressed in all skeletal muscle: 443.2 -TATDN1 CDA11 ENSG00000147687 TatD DNase domain containing 1 8 124488485-124539458 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023634, HPA053045 Uncertain Supported Nucleoplasm Expressed in all thyroid gland: 61.9 -FAM83A BJ-TSA-9, MGC14128 ENSG00000147689 Family with sequence similarity 83, member A 8 123178960-123210079 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052615 Approved Nucleoplasm Tissue enriched 8 esophagus: 78.2 seminal vesicle: 9.3 -GSDMC MLZE ENSG00000147697 Gasdermin C 8 129748196-129786888 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023670, HPA024767, HPA026317 Supported Validated Mitochondria Tissue enhanced 0 esophagus: 20.1;skin: 44.4;spleen: 21.9 tonsil: 6.7 -FAM135B C8ORFK32 ENSG00000147724 Family with sequence similarity 135, member B 8 138130023-138496822 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023911, HPA023950, HPA024815 Uncertain Approved Nucleoplasm
Nuclear membrane Group enriched 7 adrenal gland: 3.6;cerebral cortex: 8.3;testis: 7.2 colon: 0.8 -ZNF7 HF.16, KOX4 ENSG00000147789 Zinc finger protein 7 8 144827464-144847509 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA030296, HPA059090 Uncertain Approved Mitochondria Expressed in all testis: 31.4 -ARHGAP39 CrGAP, KIAA1688, Vilse ENSG00000147799 Rho GTPase activating protein 39 8 144529179-144605816 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044491 Approved Nucleoplasm
Microtubules
Cytokinetic bridge
Cytosol Tissue enhanced 0 testis: 16.5 cerebral cortex: 7.3 -SLC39A4 AEZ, AWMS2, ZIP4 ENSG00000147804 Solute carrier family 39 (zinc transporter), member 4 8 144409742-144416895 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 8 duodenum: 138.0;small intestine: 97.8 kidney: 14.3 -NAPRT NAPRT1, PP3856 ENSG00000147813 Nicotinate phosphoribosyltransferase 8 143574785-143578649 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023739, HPA024017, CAB068206, CAB068207 Approved Approved Nucleus
Golgi apparatus
Cytosol Tissue enhanced 0 duodenum: 22.0;small intestine: 21.1 bone marrow: 9.7 -VLDLR CARMQ1, CHRMQ1, VLDLRCH ENSG00000147852 Very low density lipoprotein receptor 9 2621834-2660053 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB032462, HPA051312 Uncertain Approved Vesicles
Cytokinetic bridge
Microtubule organizing center Tissue enhanced 0 ovary: 109.9;parathyroid gland: 123.5 heart muscle: 44.5 -AK3 AK3L1, AK6, AKL3L1 ENSG00000147853 Adenylate kinase 3 9 4709559-4742043 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063324 Supported Supported Mitochondria Expressed in all kidney: 105.9 -UHRF2 MGC33463, NIRF, RNF107, TDRD23, URF2 ENSG00000147854 Ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 9 6413151-6507054 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026633, HPA026697 Validated Nucleoplasm Expressed in all bone marrow: 32.9 -NFIB NFI-RED, NFIB2, NFIB3 ENSG00000147862 Nuclear factor I/B 9 14081843-14398983 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003956 Supported Supported Nucleus
Nucleoli fibrillar center Mixed breast: 44.4 -CER1 DAND4 ENSG00000147869 Cerberus 1, DAN family BMP antagonist 9 14719724-14722717 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA019917 Uncertain Tissue enriched 6 epididymis: 1.3 endometrium: 0.2 -PLIN2 ADFP, ADRP ENSG00000147872 Perilipin 2 9 19108375-19149290 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016607, CAB037331 Supported Supported Lipid droplets Expressed in all liver: 450.0 -IFNA5 IFN-alphaG ENSG00000147873 Interferon, alpha 5 9 21304326-21305312 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected epididymis: 0.2 -HAUS6 dgt6, FAM29A, FLJ20060, KIAA1574 ENSG00000147874 HAUS augmin-like complex, subunit 6 9 19053143-19103119 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020960, HPA020965 Approved Supported Nuclear speckles
Microtubule organizing center
Cytosol Tissue enhanced 0 testis: 43.1 lymph node: 13.5 -CDKN2B CDK4I, INK4B, MTS2, P15, p15INK4b, TP15 ENSG00000147883 Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 9 22002903-22009363 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB000349, HPA052838, HPA063327 Uncertain Approved Nucleoplasm Mixed small intestine: 33.3 -IFNA16 IFN-alphaO ENSG00000147885 Interferon, alpha 16 9 21216373-21217311 Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level HPA047557 Uncertain Not detected epididymis: 0.0 -CDKN2A ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf ENSG00000147889 Cyclin-dependent kinase inhibitor 2A 9 21967753-21995301 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000093, CAB000445, CAB018232, HPA047838 Uncertain Validated Nucleoli Mixed parathyroid gland: 7.5 -C9orf72 MGC23980 ENSG00000147894 Chromosome 9 open reading frame 72 9 27546545-27573866 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023873 Uncertain Expressed in all testis: 32.0 -IFNK ENSG00000147896 Interferon, kappa 9 27524314-27526498 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.1 -ZCCHC7 AIR1, FLJ22611 ENSG00000147905 Zinc finger, CCHC domain containing 7 9 37120539-37358149 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020600, HPA021088, HPA029522 Uncertain Validated Nucleoli
Cytosol Expressed in all lymph node: 28.8 -FBXO10 FBX10 ENSG00000147912 F-box protein 10 9 37510892-37576349 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002863, HPA072721 Uncertain Approved Nucleus
Cytosol Mixed testis: 16.5 -SIGMAR1 OPRS1, SR-BP1 ENSG00000147955 Sigma non-opioid intracellular receptor 1 9 34634722-34637809 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013470, HPA018002, HPA024071 Approved Expressed in all liver: 67.8 -CBWD5 ENSG00000147996 COBW domain containing 5 9 65668805-65734041 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042759, HPA042813 Approved Approved Plasma membrane Expressed in all breast: 21.6 -CEP78 C9orf81, FLJ12643 ENSG00000148019 Centrosomal protein 78kDa 9 78236062-78279690 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048846 Approved Tissue enhanced 0 testis: 30.6 endometrium: 9.9 -NTRK2 TRKB ENSG00000148053 Neurotrophic tyrosine kinase, receptor, type 2 9 84668551-85027070 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007637 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 441.0;thyroid gland: 214.8 breast: 81.9 -IDNK bA522I20.2, C9orf103 ENSG00000148057 IdnK, gluconokinase homolog (E. coli) 9 83623049-83644130 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020378, HPA058429 Approved Approved Mitochondria
Cytosol Mixed kidney: 50.2 -SHC3 N-Shc, NSHC, SHCC ENSG00000148082 SHC (Src homology 2 domain containing) transforming protein 3 9 89005771-89178767 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031427, HPA046656, HPA072448 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 45.5 parathyroid gland: 12.4 -AUH ENSG00000148090 AU RNA binding protein/enoyl-CoA hydratase 9 91213815-91361913 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004171 Supported Expressed in all kidney: 65.0 -HIATL1 FLJ14753 ENSG00000148110 Hippocampus abundant transcript-like 1 9 94374551-94461042 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA017978 Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 251.1 -C9orf3 AOPEP, AP-O, APO, C90RF3, FLJ14675 ENSG00000148120 Chromosome 9 open reading frame 3 9 94726701-95087218 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA004633, HPA072729 Approved Approved Cell Junctions Expressed in all skin: 50.1 -PLPPR1 FLJ20300, LPPR1, MGC26189, PRG-3 ENSG00000148123 Phospholipid phosphatase related 1 9 101028709-101325135 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014760, HPA014968, HPA014979 Supported Approved Nucleoplasm Group enriched 6 cerebral cortex: 23.9;kidney: 15.7 epididymis: 3.2 -OR13C4 ENSG00000148136 Olfactory receptor, family 13, subfamily C, member 4 9 104526253-104527209 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -ZNF462 DKFZP762N2316, KIAA1803, Zfp462 ENSG00000148143 Zinc finger protein 462 9 106863097-107013634 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022283 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 15.5 -INIP C9orf80, HSPC043, hSSBIP1, MISE, SOSS-C ENSG00000148153 INTS3 and NABP interacting protein 9 112683926-112718236 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020382 Approved Supported Nucleoplasm Mixed thyroid gland: 17.5 -UGCG GCS ENSG00000148154 UDP-glucose ceramide glucosyltransferase 9 111896766-111935369 Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024124 Approved Expressed in all adrenal gland: 84.4 -ACTL7B Tact1 ENSG00000148156 Actin-like 7B 9 108854589-108856967 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA021803, HPA024664 Supported Tissue enriched 593 testis: 59.3 epididymis: 0.0 -SNX30 ATG24A ENSG00000148158 Sorting nexin family member 30 9 112750838-112881671 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019346 Uncertain Approved Nucleus
Nucleoli
Cytosol Mixed lung: 32.2 -STOM BND7, EPB7, EPB72 ENSG00000148175 Stomatin 9 121338988-121370304 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010961, HPA011419 Approved Validated Cytosol Expressed in all adipose tissue: 461.2 -GSN DKFZp313L0718 ENSG00000148180 Gelsolin 9 121207794-121332843 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010823, CAB016728, CAB036009, HPA054026 Supported Supported Actin filaments Expressed in all adipose tissue: 1336.6 -MRRF RRF ENSG00000148187 Mitochondrial ribosome recycling factor 9 122264603-122331343 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047177, HPA049987 Supported Approved Microtubules
Cytokinetic bridge Expressed in all parathyroid gland: 33.9 -NR6A1 CT150, GCNF, GCNF1, RTR ENSG00000148200 Nuclear receptor subfamily 6, group A, member 1 9 124517275-124771310 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA031461, HPA045145 Supported Nucleus Tissue enriched 8 testis: 42.5 thyroid gland: 5.1 -CRB2 FLJ16786, FLJ38464 ENSG00000148204 Crumbs family member 2 9 123356170-123380324 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043674 Uncertain Tissue enhanced 0 cerebral cortex: 9.4 kidney: 2.1 -OR5C1 hRPK-465_F_21, OR5C2P, OR9-F ENSG00000148215 Olfactory receptor, family 5, subfamily C, member 1 9 122788933-122789895 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -ALAD ALADH, PBGS ENSG00000148218 Aminolevulinate dehydratase 9 113386317-113401333 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021023, HPA022124 Supported Expressed in all adrenal gland: 147.9 -ASTN2 KIAA0634 ENSG00000148219 Astrotactin 2 9 116425225-117415070 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027035 Uncertain Approved Nucleoplasm
Cytosol Expressed in all prostate: 42.3 -WDR31 FLJ35921 ENSG00000148225 WD repeat domain 31 9 113313222-113340298 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA019340, HPA019347 Approved Approved Nuclear bodies
Cytosol Tissue enhanced 0 parathyroid gland: 16.3 testis: 9.2 -POLE3 CHARAC17, CHRAC17, p17, Ybl1 ENSG00000148229 Polymerase (DNA directed), epsilon 3, accessory subunit 9 113407235-113410672 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047945 Uncertain Approved Nucleus
Nucleoli Expressed in all testis: 76.2 -SURF4 ERV29, FLJ22993, MGC102753 ENSG00000148248 Surfeit 4 9 133361449-133376166 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064613 Approved Expressed in all small intestine: 84.4 -GBGT1 A3GALNT, FS, MGC44848, UDP-GalNAc ENSG00000148288 Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 9 133152948-133163945 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA051298 Approved Mixed placenta: 15.5 -SURF1 ENSG00000148290 Surfeit 1 9 133351755-133356676 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033946 Uncertain Expressed in all epididymis: 46.0 -SURF2 ENSG00000148291 Surfeit 2 9 133356552-133361169 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044340, HPA052213 Approved Validated Nucleus
Nucleoli Expressed in all testis: 39.1 -SURF6 FLJ30322, RRP14 ENSG00000148296 Surfeit 6 9 133328774-133336398 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023608, HPA074622 Approved Validated Nucleus
Nucleoli Mixed ovary: 8.8 -MED22 Med24, SURF5 ENSG00000148297 Mediator complex subunit 22 9 133338323-133348131 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020391, HPA063694 Uncertain Approved Nucleoplasm Expressed in all parathyroid gland: 10.7 -REXO4 hPMC2, XPMC2H ENSG00000148300 REX4 homolog, 3'-5' exonuclease 9 133406059-133418096 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047006 Uncertain Supported Nucleus
Nucleoli Expressed in all testis: 11.3 -RPL7A L7A, SURF3, TRUP ENSG00000148303 Ribosomal protein L7a 9 133348214-133351426 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 2609.1 -GTF3C5 TFiiiC2-63, TFIIIC63, TFIIICepsilon ENSG00000148308 General transcription factor IIIC, polypeptide 5, 63kDa 9 133030675-133058503 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067063, HPA069805 Supported Validated Nucleoplasm Expressed in all ovary: 48.1 -ASB6 ENSG00000148331 Ankyrin repeat and SOCS box containing 6 9 129634604-129642169 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004341 Approved Expressed in all cerebral cortex: 22.8 -PTGES2 C9orf15, FLJ14038 ENSG00000148334 Prostaglandin E synthase 2 9 128120693-128128462 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020631, HPA020733 Approved Approved Mitochondria Expressed in all skeletal muscle: 35.1 -NTMT1 AD-003, C9orf32, HOMT1A, METTL11A ENSG00000148335 N-terminal Xaa-Pro-Lys N-methyltransferase 1 9 129608884-129636131 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020092, HPA058420 Uncertain Validated Nucleoplasm
Cytosol Expressed in all testis: 90.4 -CIZ1 LSFR1, ZNF356 ENSG00000148337 CDKN1A interacting zinc finger protein 1 9 128166064-128204383 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020380, HPA020387 Uncertain Validated Nucleoplasm Expressed in all testis: 94.3 -SLC25A25 KIAA1896, MCSC, PCSCL ENSG00000148339 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 9 128068201-128109245 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020381 Uncertain Supported Vesicles
Mitochondria Expressed in all gallbladder: 63.1 -SH3GLB2 KIAA1848 ENSG00000148341 SH3-domain GRB2-like endophilin B2 9 129007036-129028303 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021438, HPA024734 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 92.4 -FAM73B C9orf54, FLJ00199, FLJ14596 ENSG00000148343 Family with sequence similarity 73, member B 9 129036621-129072082 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041363 Approved Approved Cell Junctions
Cytosol Mixed small intestine: 15.8 -PTGES MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12 ENSG00000148344 Prostaglandin E synthase 9 129738331-129753047 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045064 Supported Supported Endoplasmic reticulum Tissue enhanced 0 placenta: 82.2;seminal vesicle: 118.1 urinary bladder: 37.5 -LCN2 24p3, NGAL ENSG00000148346 Lipocalin 2 9 128149071-128153455 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002695, CAB016549, CAB016550 Supported Tissue enhanced 0 bone marrow: 1855.7;gallbladder: 3437.6 cervix: 1153.6 -LRSAM1 CMT2P, FLJ31641 ENSG00000148356 Leucine rich repeat and sterile alpha motif containing 1 9 127451486-127503501 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021403, HPA021844, CAB037304 Supported Approved Cytosol Expressed in all cerebral cortex: 20.9 -HMCN2 DKFZp434P0216, FLJ23816 ENSG00000148357 Hemicentin 2 9 130265882-130434123 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053903, HPA070647 Approved Approved Vesicles Mixed small intestine: 11.6 -GPR107 FLJ20998, KIAA1624, LUSTR1, RP11-88G17 ENSG00000148358 G protein-coupled receptor 107 9 130053426-130140169 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031704 Supported Approved Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 55.1 -C9orf142 PAXX ENSG00000148362 Chromosome 9 open reading frame 142 9 136992418-136993984 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045268 Uncertain Supported Nucleus Expressed in all spleen: 22.3 -IDI2 IPPI2 ENSG00000148377 Isopentenyl-diphosphate delta isomerase 2 10 1018907-1025859 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 37 skeletal muscle: 76.3 heart muscle: 2.0 -INPP5E CORS1, JBTS1, PPI5PIV ENSG00000148384 Inositol polyphosphate-5-phosphatase E 9 136428619-136439822 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065758 Approved Expressed in all testis: 16.0 -LCN9 ENSG00000148386 Lipocalin 9 9 135663322-135666422 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 1.1 cerebral cortex: 0.6 -SEC16A KIAA0310, p250, Sec16L ENSG00000148396 SEC16 homolog A, endoplasmic reticulum export factor 9 136440096-136483759 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005684 Supported Supported Endoplasmic reticulum
Golgi apparatus Expressed in all stomach: 26.6 -DPH7 C9orf112, FLJ90634, RRT2, WDR85 ENSG00000148399 Diphthamide biosynthesis 7 9 137554904-137578935 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022911 Uncertain Approved Nuclear bodies Expressed in all fallopian tube: 23.0 -NOTCH1 TAN1 ENSG00000148400 Notch 1 9 136494444-136545862 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008112, CAB022466, HPA067168 Supported Approved Nucleoplasm Expressed in all skin: 24.0 -CACNA1B CACNL1A5, CACNN, Cav2.2 ENSG00000148408 Calcium channel, voltage-dependent, N type, alpha 1B subunit 9 137877789-138124624 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044347 Uncertain Group enriched 8 adrenal gland: 3.7;cerebral cortex: 14.9;fallopian tube: 4.8;testis: 7.6 prostate: 1.0 -NACC2 BEND9, BTBD14A, BTBD31, MGC23427 ENSG00000148411 NACC family member 2, BEN and BTB (POZ) domain containing 9 136006537-136095285 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047924, HPA052962 Approved Approved Nucleoli
Mitochondria Expressed in all cerebral cortex: 46.9 -PROSER2 C10orf47, MGC35403 ENSG00000148426 Proline and serine rich 2 10 11823339-11872277 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041337 Uncertain Uncertain Plasma membrane
Cytosol Mixed placenta: 10.8 -USP6NL KIAA0019, RN-tre, RNTRE, TRE2NL, USP6NL-IT1 ENSG00000148429 USP6 N-terminal like 10 11453946-11611754 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039196 Approved Mixed testis: 44.8 -COMMD3 BUP, C10orf8 ENSG00000148444 COMM domain containing 3 10 22315974-22320308 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036584 Approved Expressed in all breast: 52.7 -MSRB2 CBS-1, CBS1, CGI-131, MSRB, PILB ENSG00000148450 Methionine sulfoxide reductase B2 10 23095506-23122013 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027933 Approved Mixed heart muscle: 28.7 -PDSS1 COQ1, TPRT, TPT ENSG00000148459 Prenyl (decaprenyl) diphosphate synthase, subunit 1 10 26697659-26746798 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038032, HPA042741 Uncertain Approved Cytosol Mixed duodenum: 18.9 -FAM171A1 C10orf38, FLJ12884 ENSG00000148468 Family with sequence similarity 171, member A1 10 15211643-15371062 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051345 Approved Approved Nucleoplasm
Plasma membrane Mixed cerebral cortex: 73.4 -FAM188A C10orf97, CARP, DERP5, FLJ13397, my042 ENSG00000148481 Family with sequence similarity 188, member A 10 15778170-15860520 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038400, HPA038406 Uncertain Supported Nucleoplasm
Nuclear membrane Expressed in all testis: 39.0 -SLC39A12 FLJ30499 ENSG00000148482 Solute carrier family 39 (zinc transporter), member 12 10 17951839-18043292 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 28 cerebral cortex: 25.4 breast: 0.8 -TMEM236 bA162I21.2, bA16O1.2, FAM23A, FAM23B ENSG00000148483 Transmembrane protein 236 10 17752252-17800868 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 9 colon: 14.7;duodenum: 22.7;rectum: 15.8;small intestine: 38.4 appendix: 2.4 -RSU1 FLJ31034, RSP-1 ENSG00000148484 Ras suppressor protein 1 10 16590611-16817528 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025927 Uncertain Approved Vesicles Expressed in all smooth muscle: 58.1 -ST8SIA6 SIAT8F ENSG00000148488 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 10 17318383-17454330 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011635, HPA072708 Uncertain Uncertain Endoplasmic reticulum Tissue enhanced 0 breast: 13.3;lung: 18.3 epididymis: 9.4 -PARD3 ASIP, Baz, Bazooka, PAR3, PARD3A, PPP1R118 ENSG00000148498 Par-3 family cell polarity regulator 10 34109560-34815325 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030443 Approved Validated Cell Junctions Mixed skin: 68.8 -ANKRD30A NY-BR-1 ENSG00000148513 Ankyrin repeat domain 30A 10 37125788-37384111 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 15 breast: 49.0 testis: 3.3 -ZEB1 AREB6, BZP, FECD6, NIL-2-A, PPCD3, TCF8, ZEB, Zfhep, Zfhx1a ENSG00000148516 Zinc finger E-box binding homeobox 1 10 31318495-31529814 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027524, CAB058686 Supported Supported Nucleoplasm Mixed endometrium: 78.7 -FAM13C FAM13C1 ENSG00000148541 Family with sequence similarity 13, member C 10 59246129-59363181 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037888 Approved Approved Nucleoplasm
Cytosol Mixed cerebral cortex: 39.5 -NRBF2 COPR1, COPR2, DKFZp564C1664, FLJ30395 ENSG00000148572 Nuclear receptor binding factor 2 10 63133247-63155031 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021670, HPA059477 Uncertain Approved Nucleoplasm
Cytosol Expressed in all spleen: 30.9 -A1CF ACF, ACF64, ACF65, APOBEC1CF, ASP ENSG00000148584 APOBEC1 complementation factor 10 50799409-50885675 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037779, HPA044079 Supported Supported Nucleoplasm Tissue enhanced 0 duodenum: 24.2;liver: 75.9;small intestine: 30.4 kidney: 13.3 -CDHR1 CORD15, KIAA1775, PCDH21, RP65 ENSG00000148600 Cadherin-related family member 1 10 84194635-84219621 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036819 Supported Group enriched 5 rectum: 58.7;skin: 252.8 colon: 29.7 -LRIT1 DKFZP434K091, FIGLER9, LRRC21, PAL ENSG00000148602 Leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 10 84231593-84241461 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 69 testis: 6.8 epididymis: 0.0 -RGR RP44 ENSG00000148604 Retinal G protein coupled receptor 10 84245053-84259960 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 11 cerebral cortex: 16.1 epididymis: 1.4 -POLR3A hRPC155, RPC1, RPC155 ENSG00000148606 Polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 10 77969251-78029545 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037926 Uncertain Supported Nucleoplasm Expressed in all cerebral cortex: 17.9 -HERC4 DKFZP564G092, KIAA1593 ENSG00000148634 HECT and RLD domain containing E3 ubiquitin protein ligase 4 10 67921899-68075348 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045453, HPA070301 Uncertain Supported Nucleoli fibrillar center
Cytosol Expressed in all testis: 32.4 -C10orf11 CDA017, OCA7 ENSG00000148655 Chromosome 10 open reading frame 11 10 75431453-76560167 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047446, HPA050419 Approved Supported Nucleus
Cytosol Mixed adrenal gland: 72.2 -CAMK2G CAMKG ENSG00000148660 Calcium/calmodulin-dependent protein kinase II gamma 10 73812501-73874591 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040656, HPA051783, HPA051785, HPA053973 Approved Approved Plasma membrane
Cell Junctions
Cytosol Expressed in all cerebral cortex: 119.4 -ADIRF AFRO, APM2, C10orf116 ENSG00000148671 Adipogenesis regulatory factor 10 86968192-86983934 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026810 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 adipose tissue: 266.0 small intestine: 147.2 -GLUD1 GDH, GLUD ENSG00000148672 Glutamate dehydrogenase 1 10 87050486-87094866 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042492, HPA044839, HPA061369 Approved Supported Mitochondria Expressed in all liver: 457.5 -ANKRD1 ALRP, C-193, CARP, CVARP, MCARP ENSG00000148677 Ankyrin repeat domain 1 (cardiac muscle) 10 90912096-90921276 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038736 Supported Supported Nucleus
Nucleoli fibrillar center Tissue enriched 104 heart muscle: 3570.9 lung: 34.4 -HTR7 5-HT7 ENSG00000148680 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 10 90740823-90857698 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB022708 Uncertain Supported Nuclear speckles
Plasma membrane
Cytosol Group enriched 8 parathyroid gland: 43.9;testis: 16.0 urinary bladder: 3.9 -RPP30 TSG15 ENSG00000148688 Ribonuclease P/MRP 30kDa subunit 10 90871716-90908553 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037578 Approved Approved Nucleus
Nucleoli
Microtubule ends
Cytosol Expressed in all testis: 50.4 -FRA10AC1 C10orf4 ENSG00000148690 Fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 10 93667883-93702572 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039204 Approved Expressed in all cerebral cortex: 21.4 -ADD3 ADDL ENSG00000148700 Adducin 3 (gamma) 10 109996368-110135565 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009797, HPA035696 Supported Supported Plasma membrane Expressed in all thyroid gland: 167.8 -HABP2 FSAP, HABP, HGFAL, PHBP ENSG00000148702 Hyaluronan binding protein 2 10 113550837-113589602 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019518 Approved Group enriched 12 gallbladder: 56.0;liver: 225.6 stomach: 11.5 -VAX1 ENSG00000148704 Ventral anterior homeobox 1 10 117128521-117138301 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA028946 Uncertain Approved Nucleus
Nucleoli Tissue enhanced 0 cerebral cortex: 1.4 testis: 0.5 -DNAJB12 DJ10, FLJ20027 ENSG00000148719 DnaJ (Hsp40) homolog, subfamily B, member 12 10 72332830-72355230 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010642 Approved Supported Endoplasmic reticulum Expressed in all parathyroid gland: 47.2 -EIF4EBP2 ENSG00000148730 Eukaryotic translation initiation factor 4E binding protein 2 10 70404379-70428618 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019415, HPA037410, HPA061665 Approved Approved Nucleoplasm
Mitochondria Expressed in all adipose tissue: 74.1 -NPFFR1 GPR147, NPFF1R1, OT7T022 ENSG00000148734 Neuropeptide FF receptor 1 10 70247329-70283676 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037521 Uncertain Tissue enhanced 0 testis: 2.1 lymph node: 0.8 -PLEKHS1 bA211N11.2, C10orf81, FLJ23537 ENSG00000148735 Pleckstrin homology domain containing, family S member 1 10 113751454-113783429 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037583 Approved Centrosome Tissue enhanced 0 cervix, uterine: 88.1 duodenum: 42.2 -TCF7L2 TCF-4, TCF4 ENSG00000148737 Transcription factor 7-like 2 (T-cell specific, HMG-box) 10 112950250-113167678 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013535, HPA038800 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all endometrium: 33.6 -MKI67 MIB-, PPP1R105 ENSG00000148773 Marker of proliferation Ki-67 10 128096659-128126385 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000058, HPA000451, HPA001164, CAB068198 Supported Validated Nucleus
Nucleoli
Nuclear bodies Tissue enhanced 0 bone marrow: 28.9 lymph node: 18.1 -CYP17A1 CPT7, CYP17, P450C17, S17AH ENSG00000148795 Cytochrome P450, family 17, subfamily A, polypeptide 1 10 102830531-102837533 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048533 Supported Tissue enriched 25 adrenal gland: 4500.7 testis: 180.3 -INA NEF5, NF-66 ENSG00000148798 Internexin neuronal intermediate filament protein, alpha 10 103277163-103290351 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002059, HPA008057 Supported Supported Supported Nucleoplasm
Nuclear membrane
Intermediate filaments Tissue enriched 6 cerebral cortex: 89.2 adrenal gland: 16.1 -FUOM C10orf125, FLJ26016, FucM, FucU ENSG00000148803 Fucose mutarotase 10 133355154-133358035 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039207 Uncertain Tissue enhanced 0 liver: 74.5 duodenum: 52.3 -LRRC27 KIAA1674 ENSG00000148814 Leucine rich repeat containing 27 10 132332154-132379918 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA037595 Approved Nucleus
Golgi apparatus Tissue enhanced 0 testis: 100.6 fallopian tube: 20.9 -MTG1 GTPBP7 ENSG00000148824 Mitochondrial ribosome-associated GTPase 1 10 133394094-133421307 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037826, HPA037827 Approved Supported Mitochondria Expressed in all testis: 29.4 -NKX6-2 GTX, NKX6.1, NKX6B ENSG00000148826 NK6 homeobox 2 10 132783179-132786052 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 26 cerebral cortex: 15.8;stomach: 17.1 testis: 0.6 -PAOX PAO ENSG00000148832 Polyamine oxidase (exo-N4-amino) 10 133379234-133391694 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA047782 Uncertain Nucleoplasm
Centrosome Tissue enhanced 0 testis: 7.6 cerebral cortex: 3.2 -GSTO1 GSTTLp28, P28 ENSG00000148834 Glutathione S-transferase omega 1 10 104235356-104267459 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037603, HPA037604 Supported Expressed in all liver: 265.4 -TAF5 TAF2D, TAFII100 ENSG00000148835 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 10 103367967-103389065 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006195, HPA006474 Supported Supported Nucleoplasm Tissue enhanced 0 testis: 20.6 lymph node: 5.2 -PPRC1 KIAA0595, MGC74642, PRC ENSG00000148840 Peroxisome proliferator-activated receptor gamma, coactivator-related 1 10 102132994-102150331 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038511, HPA057571 Approved Validated Nucleoplasm Expressed in all skin: 20.7 -ITPRIP bA127L20.2, DANGER, KIAA1754 ENSG00000148841 Inositol 1,4,5-trisphosphate receptor interacting protein 10 104309698-104338404 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043626 Uncertain Vesicles Expressed in all bone marrow: 135.4 -CNNM2 ACDP2 ENSG00000148842 Cyclin and CBS domain divalent metal cation transport mediator 2 10 102918293-103090221 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059954, HPA071631 Validated Vesicles Tissue enhanced 0 parathyroid gland: 33.5 placenta: 12.4 -PDCD11 ALG-4, KIAA0185, RRP5 ENSG00000148843 Programmed cell death 11 10 103396648-103446292 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017924, CAB026472 Approved Supported Nucleoli
Vesicles Expressed in all testis: 27.9 -ADAM12 MCMPMltna, MLTN ENSG00000148848 ADAM metallopeptidase domain 12 10 126012381-126388455 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030866, HPA030867, HPA030868 Supported Supported Plasma membrane Tissue enriched 8 placenta: 236.1 cervix: 29.5 -RGS10 ENSG00000148908 Regulator of G-protein signaling 10 10 119499828-119542708 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004559, HPA021305, HPA058485 Supported Supported Nucleus
Plasma membrane Expressed in all lymph node: 139.8 -BTBD10 GMRP-1, GMRP1, MGC13007 ENSG00000148925 BTB (POZ) domain containing 10 11 13388001-13463297 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046777 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all testis: 67.5 -ADM AM ENSG00000148926 Adrenomedullin 11 10304680-10307397 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB016075 Approved Expressed in all placenta: 157.8 -GAS2 ENSG00000148935 Growth arrest-specific 2 11 22625642-22813055 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058904 Supported Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Tissue enhanced 0 liver: 20.3 kidney: 5.8 -SLC5A12 MGC52019, SMCT2 ENSG00000148942 Solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 11 26667019-26723427 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA060904 Supported Tissue enhanced 0 epididymis: 57.8;kidney: 172.6 small intestine: 34.0 -LIN7C FLJ11215, LIN-7-C, LIN-7C, Lin7c, MALS-3, VELI3 ENSG00000148943 Lin-7 homolog C (C. elegans) 11 27494576-27506773 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051118 Approved Expressed in all thyroid gland: 24.2 -LRRC4C KIAA1580, NGL-1 ENSG00000148948 Leucine rich repeat containing 4C 11 40114203-41459773 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051335, HPA054800 Approved Approved Cytosol Tissue enriched 7 cerebral cortex: 34.5 cervix: 4.7 -IMMP1L FLJ25059, IMMP1 ENSG00000148950 Inner mitochondrial membrane peptidase subunit 1 11 31432401-31509645 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Expressed in all epididymis: 44.8 -SAA4 C-SAA, CSAA ENSG00000148965 Serum amyloid A4, constitutive 11 18231349-18236893 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026061, HPA060139 Supported Tissue enriched 42 liver: 771.6 cervix: 18.4 -PGAP2 CWH43-N, FRAG1, MRT21 ENSG00000148985 Post-GPI attachment to proteins 2 11 3797724-3826371 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA063099 Approved Approved Microtubules Expressed in all epididymis: 258.9 -TUT1 FLJ21850, FLJ22267, FLJ22347, PAPD2, RBM21, TUTase ENSG00000149016 Terminal uridylyl transferase 1, U6 snRNA-specific 11 62575045-62592177 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069055, HPA071838 Supported Nucleus
Cytosol Expressed in all fallopian tube: 17.3 -SCGB1A1 CC10, CC16, CCSP, UGB ENSG00000149021 Secretoglobin, family 1A, member 1 (uteroglobin) 11 62405103-62423195 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025686, HPA031828 Supported Tissue enriched 9 lung: 4755.1 fallopian tube: 513.6 -SYT8 DKFZp434K0322 ENSG00000149043 Synaptotagmin VIII 11 1828307-1837521 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052700 Uncertain Approved Nucleoplasm
Cell Junctions Group enriched 5 gallbladder: 26.7;skin: 80.3;urinary bladder: 25.5 seminal vesicle: 8.5 -ZNF214 ENSG00000149050 Zinc finger protein 214 11 6999318-7020368 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055391 Uncertain Mixed fallopian tube: 6.8 -ZNF215 ZKSCAN11, ZSCAN43 ENSG00000149054 Zinc finger protein 215 11 6926404-6984632 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA047243, HPA051010 Approved Approved Nucleoplasm
Vesicles Mixed lymph node: 4.8 -HSD17B12 KAR, SDR12C1 ENSG00000149084 Hydroxysteroid (17-beta) dehydrogenase 12 11 43556436-43856617 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016427 Approved Expressed in all parathyroid gland: 205.0 -APIP APIP2, CGI-29, Mmrp19 ENSG00000149089 APAF1 interacting protein 11 34853094-34916499 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021188, HPA024131 Approved Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 33.0 -PAMR1 DKFZP586H2123, RAMP ENSG00000149090 Peptidase domain containing associated with muscle regeneration 1 11 35431823-35530300 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cervix, uterine: 86.5;endometrium: 91.9 placenta: 75.5 -DGKZ DAGK5, DAGK6, DGK-ZETA, hDGKzeta ENSG00000149091 Diacylglycerol kinase, zeta 11 46332905-46380554 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051336 Supported Supported Nuclear speckles Expressed in all cerebral cortex: 133.0 -EIF3M eIF3m, FLJ29030, GA17, hfl-B5, PCID1, TANGO7 ENSG00000149100 Eukaryotic translation initiation factor 3, subunit M 11 32583798-32606262 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031063 Approved Supported Cytosol Expressed in all fallopian tube: 232.5 -TNKS1BP1 FLJ45975, KIAA1741, TAB182 ENSG00000149115 Tankyrase 1 binding protein 1, 182kDa 11 57299638-57324952 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037929, HPA037930 Supported Expressed in all skin: 79.3 -GLYAT ACGNAT, GAT ENSG00000149124 Glycine-N-acyltransferase 11 58640426-58731974 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040251, HPA044094 Supported Group enriched 10 kidney: 579.6;liver: 353.8 adipose tissue: 47.4 -SERPING1 C1-INH, C1IN, C1NH, HAE1, HAE2 ENSG00000149131 Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 11 57597387-57614853 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026161, HPA048738 Supported Expressed in all liver: 1365.4 -OR5F1 OR11-10 ENSG00000149133 Olfactory receptor, family 5, subfamily F, member 1 11 55993681-55994625 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA059360 Uncertain Not detected epididymis: 0.0 -SSRP1 FACT80 ENSG00000149136 Structure specific recognition protein 1 11 57325985-57335877 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002697 Approved Approved Nucleus
Cytosol Expressed in all parathyroid gland: 122.9 -SLC43A1 PB39, POV1, R00504 ENSG00000149150 Solute carrier family 43 (amino acid system L transporter), member 1 11 57484534-57515786 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018813, HPA018826 Supported Approved Golgi apparatus
Vesicles
Plasma membrane Expressed in all liver: 50.0 -PTPRJ CD148, DEP1, HPTPeta ENSG00000149177 Protein tyrosine phosphatase, receptor type, J 11 47980558-48170841 CD markers, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006026 Approved Mixed parathyroid gland: 37.8 -C11orf49 FLJ22210, MGC4707 ENSG00000149179 Chromosome 11 open reading frame 49 11 46936689-47164385 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040051, HPA040280 Uncertain Approved Nuclear speckles Expressed in all cerebral cortex: 57.4 -ARFGAP2 FLJ14576, IRZ, Zfp289, ZNF289 ENSG00000149182 ADP-ribosylation factor GTPase activating protein 2 11 47164299-47177125 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016649, HPA018152 Supported Supported Golgi apparatus Expressed in all skin: 90.2 -CELF1 BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, hNab50, NAB50, NAPOR ENSG00000149187 CUGBP, Elav-like family member 1 11 47465944-47565569 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016114, HPA044597 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 130.7 -C11orf73 Hikeshi, HSPC138, HSPC179, OPI10 ENSG00000149196 Chromosome 11 open reading frame 73 11 86302211-86345931 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035063, HPA035064 Approved Expressed in all endometrium: 46.3 -CCDC81 FLJ16339, FLJ23514 ENSG00000149201 Coiled-coil domain containing 81 11 86374736-86423109 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040745, HPA040827 Uncertain Uncertain Plasma membrane Group enriched 11 fallopian tube: 45.5;testis: 10.9 endometrium: 2.6 -SESN3 MGC29667, SEST3 ENSG00000149212 Sestrin 3 11 95165513-95232541 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037935 Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 104.4 parathyroid gland: 54.5 -ENDOD1 KIAA0830 ENSG00000149218 Endonuclease domain containing 1 11 95089810-95132645 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008932, HPA010517 Supported Approved Nuclear membrane Expressed in all parathyroid gland: 97.8 -CCDC82 FLJ23518 ENSG00000149231 Coiled-coil domain containing 82 11 96352769-96389923 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038704 Uncertain Approved Nucleus
Cytosol Expressed in all testis: 55.3 -KLHL35 FLJ33790 ENSG00000149243 Kelch-like family member 35 11 75422394-75430629 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039232, HPA039864 Uncertain Approved Nucleus
Nucleoli fibrillar center
Centrosome Tissue enhanced 0 cerebral cortex: 3.6;testis: 6.1 cervix: 1.0 -TENM4 KIAA1302, ODZ4, Ten-M4 ENSG00000149256 Teneurin transmembrane protein 4 11 78652831-79440948 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019521, HPA065961 Approved Tissue enhanced 0 ovary: 21.0;parathyroid gland: 53.6 thyroid gland: 9.8 -SERPINH1 CBP1, CBP2, colligen, HSP47, SERPINH2 ENSG00000149257 Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 11 75562056-75572783 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004441, HPA029198 Supported Validated Endoplasmic reticulum Expressed in all placenta: 327.0 -CAPN5 ADNIV, HTRA3, nCL-3, VRNI ENSG00000149260 Calpain 5 11 77066932-77126155 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033237, HPA072319 Uncertain Approved Nucleus
Cytosol Mixed colon: 62.2 -INTS4 INT4, MGC16733, MST093 ENSG00000149262 Integrator complex subunit 4 11 77878720-77994678 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042378 Uncertain Approved Nucleoli Expressed in all parathyroid gland: 26.6 -PAK1 ENSG00000149269 P21 protein (Cdc42/Rac)-activated kinase 1 11 77321707-77474635 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003565, CAB005312 Supported Supported Validated Plasma membrane
Cytosol Expressed in all cerebral cortex: 186.8 -RPS3 FLJ26283, FLJ27450, MGC87870, S3 ENSG00000149273 Ribosomal protein S3 11 75399486-75422280 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063339 Uncertain Supported Endoplasmic reticulum
Cytosol Expressed in all ovary: 3526.1 -ZC3H12C KIAA1726, MCPIP3 ENSG00000149289 Zinc finger CCCH-type containing 12C 11 110093361-110171841 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038836, HPA038837 Approved Approved Nuclear membrane
Golgi apparatus Mixed thyroid gland: 13.6 -TTC12 FLJ13859, FLJ20535, TPARM ENSG00000149292 Tetratricopeptide repeat domain 12 11 113314529-113383544 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038542, HPA038543, HPA061364 Approved Approved Nucleoplasm Expressed in all testis: 91.9 -NCAM1 CD56, NCAM ENSG00000149294 Neural cell adhesion molecule 1 11 112961247-113278436 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000142, CAB018071, HPA039835 Supported Validated Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 335.9 adrenal gland: 87.0 -DRD2 ENSG00000149295 Dopamine receptor D2 11 113409615-113475691 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA015691 Supported Tissue enriched 5 adrenal gland: 11.3 smooth muscle: 2.2 -C11orf52 FLJ25219, MGC14839 ENSG00000149300 Chromosome 11 open reading frame 52 11 111918032-111926872 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038387, HPA038388 Uncertain Validated Cell Junctions Mixed kidney: 44.8 -HTR3B 5-HT3B ENSG00000149305 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 11 113904677-113946565 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039559 Approved Tissue enhanced 0 cerebral cortex: 2.8 testis: 1.1 -NPAT E14 ENSG00000149308 Nuclear protein, ataxia-telangiectasia locus 11 108157215-108222642 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045908, HPA066370 Supported Nucleoplasm
Nuclear bodies Mixed lymph node: 17.7 -ATM ATA, ATC, ATD, ATDC, TEL1, TELO1 ENSG00000149311 ATM serine/threonine kinase 11 108222484-108369102 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000102, HPA067142 Supported Supported Nucleoplasm Expressed in all lymph node: 41.6 -AASDHPPT AASD-PPT, CGI-80, LYS5 ENSG00000149313 Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 11 106075501-106098710 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020253, HPA026687 Approved Approved Mitochondria Expressed in all cerebral cortex: 82.1 -GLB1L2 ENSG00000149328 Galactosidase, beta 1-like 2 11 134331874-134378341 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA054808, HPA059955 Uncertain Supported Nucleus Tissue enhanced 0 prostate: 57.3 parathyroid gland: 52.2 -SLX4IP C20orf94, dJ1099D15.3 ENSG00000149346 SLX4 interacting protein 20 10435303-10636829 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046372 Approved Approved Cytosol Mixed parathyroid gland: 8.0 -LAMTOR1 C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1 ENSG00000149357 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 11 72085895-72103387 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002997 Approved Supported Golgi apparatus
Vesicles
Plasma membrane Expressed in all thyroid gland: 142.7 -P4HA3 C-P4Halpha(III) ENSG00000149380 Prolyl 4-hydroxylase, alpha polypeptide III 11 74235801-74311657 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007897 Supported Tissue enhanced 0 smooth muscle: 14.2 urinary bladder: 9.0 -GRIK4 GluK4, GRIK, KA1 ENSG00000149403 Glutamate receptor, ionotropic, kainate 4 11 120511759-120988904 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 10.6 thyroid gland: 2.8 -ST14 HAI, MT-SP1, PRSS14, SNC19, TMPRSS14 ENSG00000149418 Suppression of tumorigenicity 14 (colon carcinoma) 11 130159562-130210376 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047014 Approved Nucleoplasm
Vesicles Mixed small intestine: 152.0 -HYOU1 Grp170, HSP12A, ORP150 ENSG00000149428 Hypoxia up-regulated 1 11 119044189-119057202 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049296 Approved Expressed in all thyroid gland: 111.5 -GGTLC1 dJ831C21.1, dJ831C21.2, GGTLA3, GGTLA4 ENSG00000149435 Gamma-glutamyltransferase light chain 1 20 23985050-23988779 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA045635, HPA047534 Uncertain Group enriched 14 lung: 38.8;testis: 15.7 thyroid gland: 1.9 -ADAM33 C20orf153, dJ964F7.1, DKFZp434K0521 ENSG00000149451 ADAM metallopeptidase domain 33 20 3667965-3682246 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA067152, HPA071758 Approved Uncertain Nuclear speckles
Plasma membrane Mixed endometrium: 102.9 -SLC22A8 OAT3 ENSG00000149452 Solute carrier family 22 (organic anion transporter), member 8 11 62989154-63015839 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044174 Supported Tissue enriched 391 kidney: 337.6 cerebral cortex: 0.8 -CSRP2BP ATAC2, CRP2BP, dJ717M23.1, KAT14, PRO1194 ENSG00000149474 CSRP2 binding protein 20 18138118-18188387 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034224, HPA068443 Uncertain Approved Vesicles Expressed in all parathyroid gland: 21.0 -TKFC DAK, DKFZP586B1621, NET45 ENSG00000149476 Triokinase/FMN cyclase 11 61333210-61353295 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039486, HPA048186 Supported Approved Nucleus
Cytosol Expressed in all duodenum: 205.9 -MTA2 MTA1-L1, MTA1L1 ENSG00000149480 Metastasis associated 1 family, member 2 11 62593214-62601840 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005315, HPA006214, CAB017522 Supported Validated Nucleoplasm Expressed in all skin: 88.6 -TMEM138 HSPC196, JBTS16 ENSG00000149483 Transmembrane protein 138 11 61362001-61369509 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042373 Approved Approved Microtubules Expressed in all epididymis: 24.8 -FADS1 D5D, FADS6, FADSD5, LLCDL1, TU12 ENSG00000149485 Fatty acid desaturase 1 11 61799625-61829318 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042705 Approved Expressed in all adrenal gland: 89.6 -TMC2 C20orf145, dJ686C3.3 ENSG00000149488 Transmembrane channel-like 2 20 2536607-2641784 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046350 Uncertain Tissue enhanced 0 testis: 1.0 lung: 0.8 -ROM1 ROM, TSPAN23 ENSG00000149489 Retinal outer segment membrane protein 1 11 62611722-62615120 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028910 Supported Approved Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 25.5 ovary: 13.2 -EML3 ELP95, FLJ35827 ENSG00000149499 Echinoderm microtubule associated protein like 3 11 62602218-62612765 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all appendix: 38.9 -INCENP FLJ31633 ENSG00000149503 Inner centromere protein antigens 135/155kDa 11 62123973-62153163 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013292, HPA070550 Supported Supported Nucleus
Nuclear bodies
Midbody Mixed lymph node: 12.8 -ZP1 ENSG00000149506 Zona pellucida glycoprotein 1 (sperm receptor) 11 60867562-60875693 Disease related genes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected epididymis: 0.4 -OOSP2 FLJ36198, PLAC1L, TMEM122 ENSG00000149507 Oocyte secreted protein 2 11 60040275-60048044 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA050914 Approved Tissue enriched 485 testis: 48.4 epididymis: 0.0 -MS4A3 CD20L, HTM4 ENSG00000149516 Membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 11 60056587-60071128 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA019210 Supported Tissue enriched 254 bone marrow: 305.8 spleen: 1.2 -PLCH2 KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1 ENSG00000149527 Phospholipase C, eta 2 1 2425980-2505530 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 58.4 esophagus: 14.0 -CPSF7 FLJ12529 ENSG00000149532 Cleavage and polyadenylation specific factor 7, 59kDa 11 61402641-61430031 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041094 Supported Supported Nucleoplasm
Cytosol Expressed in all endometrium: 75.7 -MS4A2 APY, FCER1B, IGER, MS4A1 ENSG00000149534 Membrane-spanning 4-domains, subfamily A, member 2 11 60088261-60098466 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA059967 Supported Tissue enhanced 0 lung: 24.8 gallbladder: 18.5 -B3GAT3 GlcAT-I ENSG00000149541 Beta-1,3-glucuronyltransferase 3 11 62615296-62622175 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051328 Approved Expressed in all cerebral cortex: 37.0 -EI24 EPG4, PIG8, TP53I8 ENSG00000149547 Etoposide induced 2.4 11 125569216-125584687 Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047165, HPA051029 Uncertain Supported Endoplasmic reticulum
Golgi apparatus
Cytosol Tissue enriched 9 parathyroid gland: 1098.6 liver: 124.7 -CCDC15 FLJ13215 ENSG00000149548 Coiled-coil domain containing 15 11 124954121-125041489 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040450, HPA041738 Uncertain Approved Plasma membrane
Cytosol Tissue enriched 5 testis: 18.8 breast: 3.5 -CHEK1 CHK1 ENSG00000149554 Checkpoint kinase 1 11 125625136-125676255 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044364 Approved Nucleoplasm
Vesicles Tissue enhanced 0 parathyroid gland: 61.6;seminal vesicle: 52.5 testis: 21.8 -FEZ1 ENSG00000149557 Fasciculation and elongation protein zeta 1 (zygin I) 11 125445745-125496317 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038490 Supported Microtubules
Cytosol Tissue enriched 10 cerebral cortex: 412.6 urinary bladder: 43.0 -ESAM W117m ENSG00000149564 Endothelial cell adhesion molecule 11 124752583-124762290 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051043, HPA056293 Uncertain Approved Microtubules Expressed in all placenta: 156.5 -KIRREL3 KIAA1867, KIRRE, NEPH2 ENSG00000149571 Kin of IRRE like 3 (Drosophila) 11 126423359-127003460 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053324, HPA056320 Supported Tissue enriched 11 cerebral cortex: 20.5 adrenal gland: 1.9 -MPZL2 EVA, EVA1 ENSG00000149573 Myelin protein zero-like 2 11 118253403-118264536 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051395, HPA060740 Approved Approved Cell Junctions Tissue enhanced 0 esophagus: 210.0 urinary bladder: 122.3 -SCN2B ENSG00000149575 Sodium channel, voltage gated, type II beta subunit 11 118161951-118176673 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 5 cerebral cortex: 34.8 heart muscle: 6.7 -SIDT2 CGI-40 ENSG00000149577 SID1 transmembrane family, member 2 11 117178733-117197445 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052352 Approved Expressed in all prostate: 59.7 -TMEM25 FLJ14399 ENSG00000149582 Transmembrane protein 25 11 118531041-118547280 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012163, HPA051562 Approved Approved Golgi apparatus
Vesicles Expressed in all duodenum: 48.3 -TAGLN DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10 ENSG00000149591 Transgelin 11 117199321-117204782 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001447, HPA019467 Supported Approved Microtubules
Mitochondria
Cytosol Expressed in all smooth muscle: 11751.0 -JPH2 JP-2 ENSG00000149596 Junctophilin 2 20 44111695-44187578 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052646 Approved Tissue enhanced 0 skeletal muscle: 72.1;smooth muscle: 55.4 seminal vesicle: 47.3 -DUSP15 bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY ENSG00000149599 Dual specificity phosphatase 15 20 31847637-31870747 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA076649 Approved Plasma membrane
Cytosol Tissue enhanced 0 testis: 77.1 parathyroid gland: 16.0 -COMMD7 C20orf92, dJ1085F17.3 ENSG00000149600 COMM domain containing 7 20 32702691-32743997 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054119 Supported Vesicles Expressed in all thyroid gland: 80.0 -C20orf144 bclt, dJ63M2.6 ENSG00000149609 Chromosome 20 open reading frame 144 20 33662284-33665619 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019029 Supported Tissue enriched 431 testis: 43.0 epididymis: 0.0 -KIAA1755 RP5-1054A22.3 ENSG00000149633 KIAA1755 20 38210488-38260772 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051064 Approved Approved Nucleoli
Golgi apparatus
Vesicles Mixed cerebral cortex: 33.7 -SPATA25 C20orf165, dJ337O18.8, TSG23 ENSG00000149634 Spermatogenesis associated 25 20 45886489-45887635 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041386 Approved Golgi apparatus Mixed testis: 15.4 -OCSTAMP C20orf123, dJ257E24.3 ENSG00000149635 Osteoclast stimulatory transmembrane protein 20 46540946-46550574 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA031116 Uncertain Not detected testis: 0.2 -DSN1 C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13 ENSG00000149636 DSN1 homolog, MIS12 kinetochore complex component 20 36751791-36773818 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002813 Supported Supported Nucleus Mixed testis: 40.1 -SOGA1 C20orf117, dJ132F21.1, FLJ44670, KIAA0889, SOGA ENSG00000149639 Suppressor of glucose, autophagy associated 1 20 36777442-36863686 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043992 Approved Approved Nucleoli
Cytosol Mixed thyroid gland: 20.2 -CNBD2 C20orf152, CNMPD1, dJ954P9.1 ENSG00000149646 Cyclic nucleotide binding domain containing 2 20 35954564-36030700 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043182 Uncertain Tissue enhanced 0 testis: 37.8 epididymis: 14.8 -SPINT4 C20orf137, dJ601O1.1 ENSG00000149651 Serine peptidase inhibitor, Kunitz type 4 20 45722351-45725830 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 1613 epididymis: 340.5 seminal vesicle: 0.2 -CDH22 C20orf25, dJ998H6.1 ENSG00000149654 Cadherin 22, type 2 20 46173733-46308498 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA012164 Uncertain Group enriched 6 adrenal gland: 2.0;cerebral cortex: 10.3;fallopian tube: 2.3;skin: 5.2 testis: 0.8 -LSM14B bA11M20.3, C20orf40, FAM61B, FLJ25473, FT005, LSM13, RAP55B ENSG00000149657 LSM family member 14B 20 62122461-62135378 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041274, HPA061189 Approved Supported Nucleoli fibrillar center
Vesicles Expressed in all testis: 78.8 -YTHDF1 C20orf21, FLJ20391 ENSG00000149658 YTH N(6)-methyladenosine RNA binding protein 1 20 63195429-63216234 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 42.3 -CABLES2 C20orf150, dJ908M14.2, ik3-2 ENSG00000149679 Cdk5 and Abl enzyme substrate 2 20 62388632-62407285 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052138 Approved Nuclear bodies
Cell Junctions Tissue enriched 6 testis: 58.3 cerebral cortex: 9.0 -ORAOV1 TAOS1 ENSG00000149716 Oral cancer overexpressed 1 11 69653076-69675416 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062696 Approved Nucleoplasm Expressed in all epididymis: 21.5 -GPHA2 A2, GPA2, MGC126572, ZSIG51 ENSG00000149735 Glycoprotein hormone alpha 2 11 64934471-64935888 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 6 gallbladder: 26.4;pancreas: 76.9 testis: 7.9 -SLC22A9 FLJ23666, OAT4, OAT7, UST3 ENSG00000149742 Solute carrier family 22 (organic anion transporter), member 9 11 63369789-63410294 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 30 liver: 22.8 skeletal muscle: 0.7 -TRPT1 MGC11134 ENSG00000149743 TRNA phosphotransferase 1 11 64223799-64226254 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038705, HPA038706 Uncertain Approved Mitochondria Expressed in all testis: 44.8 -NUDT22 MGC13045 ENSG00000149761 Nudix (nucleoside diphosphate linked moiety X)-type motif 22 11 64225941-64230686 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039334, HPA053464 Approved Validated Nucleoplasm Expressed in all duodenum: 32.0 -FERMT3 KIND3, MGC10966, MIG-2, MIG2B, UNC112C, URP2 ENSG00000149781 Fermitin family member 3 11 64206678-64223886 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065231 Approved Vesicles Tissue enhanced 0 bone marrow: 114.4 lymph node: 102.9 -PLCB3 ENSG00000149782 Phospholipase C, beta 3 (phosphatidylinositol-specific) 11 64251523-64269150 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009257, HPA039279, HPA043907 Supported Validated Nucleoplasm Expressed in all duodenum: 118.1 -MRPL49 C11orf4, L49mt, NOF, NOF1 ENSG00000149792 Mitochondrial ribosomal protein L49 11 65122183-65127371 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046778 Approved Expressed in all adrenal gland: 83.8 -CDC42EP2 BORG1, CEP2 ENSG00000149798 CDC42 effector protein (Rho GTPase binding) 2 11 65314818-65322429 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038562 Approved Supported Microtubules
Cytosol Mixed adipose tissue: 45.8 -FAU asr1, FLJ22986, Fub1, Fubi, MNSFbeta, RPS30, S30 ENSG00000149806 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 11 65120628-65122473 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059015 Supported Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 1268.2 -TM7SF2 ANG1, DHCR14A, NET47 ENSG00000149809 Transmembrane 7 superfamily member 2 11 65111845-65116384 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030691, HPA072704 Approved Supported Endoplasmic reticulum
Vesicles Expressed in all adrenal gland: 161.3 -VPS51 ANG2, ANG3, C11orf2, C11orf3, FFR ENSG00000149823 Vacuolar protein sorting 51 homolog (S. cerevisiae) 11 65089324-65111860 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039650, HPA061447 Uncertain Approved Nucleoli
Golgi apparatus
Vesicles Expressed in all ovary: 102.0 -TBX6 ENSG00000149922 T-box 6 16 30085793-30091887 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed stomach: 4.5 -PPP4C PP4, PPX ENSG00000149923 Protein phosphatase 4, catalytic subunit 16 30075978-30085377 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043837 Supported Supported Nucleus
Plasma membrane
Cytosol Expressed in all testis: 77.8 -ALDOA ENSG00000149925 Aldolase A, fructose-bisphosphate 16 30053090-30070457 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004177, CAB006252 Supported Supported Cytosol Tissue enriched 7 skeletal muscle: 9379.1 esophagus: 1434.9 -FAM57B DKFZP434I2117 ENSG00000149926 Family with sequence similarity 57, member B 16 30024427-30052978 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030837 Uncertain Group enriched 12 cerebral cortex: 18.7;testis: 77.3 skeletal muscle: 3.9 -DOC2A ENSG00000149927 Double C2-like domains, alpha 16 30005509-30023270 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065676 Uncertain Nucleus
Nucleoli
Cell Junctions Group enriched 9 cerebral cortex: 69.9;testis: 21.0 ovary: 5.2 -HIRIP3 ENSG00000149929 HIRA interacting protein 3 16 29992321-29996436 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051897, HPA063205 Approved Validated Nucleus Expressed in all testis: 39.1 -TAOK2 KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2 ENSG00000149930 TAO kinase 2 16 29973641-29992261 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010650 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all testis: 36.9 -TMEM219 ENSG00000149932 Transmembrane protein 219 16 29940885-29973052 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059185 Approved Expressed in all fallopian tube: 196.0 -HMGA2 BABL, HMGIC, LIPO ENSG00000149948 High mobility group AT-hook 2 12 65824131-65966295 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017809, HPA039076 Approved Supported Nucleus
Nucleoli Mixed testis: 3.7 -MMP3 STMY, STMY1 ENSG00000149968 Matrix metallopeptidase 3 11 102835801-102843803 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007875 Uncertain Approved Vesicles Tissue enhanced 0 appendix: 26.9;endometrium: 58.7 urinary bladder: 9.2 -CNKSR2 CNK2, KIAA0902, KSR2 ENSG00000149970 Connector enhancer of kinase suppressor of Ras 2 X 21374418-21654695 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001502 Approved Golgi apparatus
Plasma membrane Tissue enriched 9 cerebral cortex: 54.1 adrenal gland: 5.8 -CNTN5 hNB-2, NB-2 ENSG00000149972 Contactin 5 11 99020953-100358885 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039492, HPA041223 Approved Supported Cytosol Tissue enhanced 0 cerebral cortex: 2.6;placenta: 3.4;thyroid gland: 3.0 fallopian tube: 1.8 -KLRF1 CLEC5C, NKp80 ENSG00000150045 Killer cell lectin-like receptor subfamily F, member 1 12 9827481-9845007 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 spleen: 25.3 bone marrow: 7.2 -CLEC1A CLEC1, MGC34328 ENSG00000150048 C-type lectin domain family 1, member A 12 10069554-10111627 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 placenta: 70.5 lung: 12.7 -MKX C10orf48, IRXL1, MGC39616 ENSG00000150051 Mohawk homeobox 10 27672875-27746060 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA006927 Uncertain Approved Nucleoplasm
Nuclear speckles Tissue enhanced 0 ovary: 13.6;prostate: 26.1 fallopian tube: 8.1 -MPP7 FLJ32798 ENSG00000150054 Membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 10 28050993-28334486 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037597, HPA037598 Supported Supported Cell Junctions Mixed esophagus: 41.3 -CCDC7 BIOT2, C10orf68, FLJ13031, FLJ32762 ENSG00000150076 Coiled-coil domain containing 7 10 32567723-32882874 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 45 testis: 93.5 epididymis: 2.0 -ITGB1 CD29, FNRB, GPIIA, MDF2, MSK12 ENSG00000150093 Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 10 32900319-33005792 Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003434 Approved Supported Endoplasmic reticulum
Plasma membrane
Focal adhesion sites Expressed in all smooth muscle: 1058.2 -FXYD4 CHIF ENSG00000150201 FXYD domain containing ion transport regulator 4 10 43371642-43376335 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA058421 Supported Tissue enriched 27 kidney: 126.8 stomach: 4.7 -TRIM48 RNF101 ENSG00000150244 Tripartite motif containing 48 11 55262182-55271119 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected skin: 0.3 -OR8K1 ENSG00000150261 Olfactory receptor, family 8, subfamily K, member 1 11 56346039-56346998 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA055233 Uncertain Not detected epididymis: 0.0 -OR5M9 ENSG00000150269 Olfactory receptor, family 5, subfamily M, member 9 11 56462469-56463401 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -PCDH15 CDHR15, DFNB23, USH1F ENSG00000150275 Protocadherin-related 15 10 53802771-55627942 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adrenal gland: 25.1;cerebral cortex: 12.3 kidney: 8.1 -CTF1 CT-1, CT1 ENSG00000150281 Cardiotrophin 1 16 30896607-30903560 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025853 Uncertain Mixed parathyroid gland: 28.1 -CWC15 AD002, C11orf5, Cwf15, HSPC148 ENSG00000150316 CWC15 spliceosome-associated protein 11 94962622-94973612 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039878 Supported Approved Nuclear speckles
Mitochondria Expressed in all testis: 78.5 -FCGR1A CD64, CD64A ENSG00000150337 Fc fragment of IgG, high affinity Ia, receptor (CD64) 1 149782671-149792518 CD markers, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 50.0;epididymis: 90.7 placenta: 38.3 -ARID5B FLJ21150, MRF2 ENSG00000150347 AT rich interactive domain 5B (MRF1-like) 10 61901300-62096944 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015037 Uncertain Approved Plasma membrane
Cytosol Expressed in all gallbladder: 62.1 -KLHL1 FLJ30047, KIAA1490, MRP2 ENSG00000150361 Kelch-like family member 1 13 69700594-70108493 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA021196 Uncertain Tissue enhanced 0 cerebral cortex: 1.9 prostate: 0.4 -CDH8 ENSG00000150394 Cadherin 8, type 2 16 61647242-62037035 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014908, HPA058444 Approved Supported Plasma membrane Group enriched 8 cerebral cortex: 27.9;seminal vesicle: 6.9 ovary: 2.1 -DCUN1D2 C13orf17, FLJ10704, FLJ20092 ENSG00000150401 DCN1, defective in cullin neddylation 1, domain containing 2 13 113455819-113490952 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039349 Uncertain Approved Plasma membrane
Cytosol Expressed in all heart muscle: 65.3 -TMCO3 C13orf11, FLJ20623 ENSG00000150403 Transmembrane and coiled-coil domains 3 13 113490995-113554590 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039561, HPA048126 Uncertain Approved Cytosol Expressed in all cervix: 49.2 -TMEM218 ENSG00000150433 Transmembrane protein 218 11 125096545-125111763 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038489 Uncertain Approved Plasma membrane
Cytosol Expressed in all fallopian tube: 21.7 -TIRAP Mal, wyatt ENSG00000150455 Toll-interleukin 1 receptor (TIR) domain containing adaptor protein 11 126283065-126298845 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054431 Uncertain Approved Nucleoplasm
Cytokinetic bridge
Cytosol Mixed parathyroid gland: 13.1 -N6AMT2 ENSG00000150456 N-6 adenine-specific DNA methyltransferase 2 (putative) 13 20728731-20773958 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040417, HPA042543 Uncertain Approved Plasma membrane
Cytosol Expressed in all endometrium: 18.0 -LATS2 ENSG00000150457 Large tumor suppressor kinase 2 13 20973032-21061547 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039191, HPA049037 Approved Supported Microtubule organizing center
Cytosol Expressed in all testis: 25.7 -SAP18 2HOR0202, MGC27131, SAP18p ENSG00000150459 Sin3A-associated protein, 18kDa 13 21140514-21149084 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011352, CAB012273 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all testis: 256.3 -ADGRL3 KIAA0768, LEC3, LPHN3 ENSG00000150471 Adhesion G protein-coupled receptor L3 4 61201258-62078335 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015027, HPA015762, CAB022698 Uncertain Tissue enhanced 0 cerebral cortex: 42.1;parathyroid gland: 30.1 cervix: 8.5 -KIAA1328 ENSG00000150477 KIAA1328 18 36829106-37232172 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040946 Approved Approved Nuclear speckles
Vesicles
Lipid droplets Expressed in all testis: 42.7 -FAM124A FLJ30707 ENSG00000150510 Family with sequence similarity 124A 13 51222334-51284241 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048182 Uncertain Approved Nucleus
Cytosol Mixed cerebral cortex: 13.9 -MIA2 FLJ22404 ENSG00000150526 Melanoma inhibitory activity 2 14 39230231-39253655 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054066, HPA055459 Supported Supported Endoplasmic reticulum Tissue enhanced 0 parathyroid gland: 20.2 small intestine: 8.3 -CTAGE5 cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, MEA6, MGEA, MGEA11, MGEA6 ENSG00000150527 CTAGE family, member 5 14 39265284-39388513 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000387, HPA000922 Uncertain Expressed in all thyroid gland: 77.3 -HNMT ENSG00000150540 Histamine N-methyltransferase 2 137964020-138016364 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035480, HPA035481 Approved Expressed in all liver: 123.8 -LYPD1 LYPDC1, MGC29643 ENSG00000150551 LY6/PLAUR domain containing 1 2 132644853-132671579 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 17 cerebral cortex: 27.3;fallopian tube: 125.8 salivary gland: 4.5 -LYPD6B CT116, LYPD7 ENSG00000150556 LY6/PLAUR domain containing 6B 2 149038107-149215262 Predicted secreted proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049239 Uncertain Tissue enhanced 0 gallbladder: 58.8;skin: 56.6 testis: 42.1 -PDCD4 H731 ENSG00000150593 Programmed cell death 4 (neoplastic transformation inhibitor) 10 110871795-110900006 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001032, HPA027214, CAB037024 Supported Approved Nucleoplasm Expressed in all parathyroid gland: 458.8 -ADRA2A ADRA2, ADRA2R, ADRAR ENSG00000150594 Adrenoceptor alpha 2A 10 111077163-111080907 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cervix: 33.1 -GPM6A GPM6 ENSG00000150625 Glycoprotein M6A 4 175632934-176002664 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017338 Supported Tissue enriched 36 cerebral cortex: 1107.6 lung: 30.7 -WDR17 ENSG00000150627 WD repeat domain 17 4 176065834-176182818 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042766 Uncertain Approved Nuclear speckles Tissue enhanced 0 cerebral cortex: 25.3;parathyroid gland: 19.0 thyroid gland: 11.0 -SPATA4 SPEF1B, TSARG2 ENSG00000150628 Spermatogenesis associated 4 4 176184638-176195671 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA019220 Supported Tissue enriched 18 testis: 241.7 fallopian tube: 13.3 -VEGFC VRP ENSG00000150630 Vascular endothelial growth factor C 4 176683538-176792727 Cancer-related genes, Disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 thyroid gland: 51.4 placenta: 30.4 -CCDC102B ACY1L, AN, C18orf14, FLJ23594, HsT1731 ENSG00000150636 Coiled-coil domain containing 102B 18 68715209-69055189 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040623, HPA048194 Approved Approved Mitochondria
Cytosol Tissue enhanced 0 placenta: 40.6 gallbladder: 21.7 -CD226 DNAM-1, DNAM1, PTA1, TLiSA1 ENSG00000150637 CD226 molecule 18 69831158-69961803 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015715 Supported Tissue enriched 11 parathyroid gland: 312.4 spleen: 28.8 -CNDP1 CN1, CPGL2, HsT2308, MGC10825 ENSG00000150656 Carnosine dipeptidase 1 (metallopeptidase M20 family) 18 74534440-74587212 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008933 Supported Group enriched 12 cerebral cortex: 102.0;liver: 23.0 duodenum: 5.2 -FSIP1 FLJ35989 ENSG00000150667 Fibrous sheath interacting protein 1 15 39600031-39782830 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041002 Uncertain Uncertain Nucleoplasm Group enriched 7 colon: 11.3;rectum: 18.6;testis: 13.5 breast: 2.1 -DLG2 chapsyn-110, PPP1R58, PSD-93, PSD93 ENSG00000150672 Discs, large homolog 2 (Drosophila) 11 83455012-85627922 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021307, HPA023896, CAB072341 Approved Approved Vesicles
Plasma membrane Tissue enhanced 0 cerebral cortex: 73.0 thyroid gland: 25.9 -CCDC83 CT148, FLJ42119, MGC34732 ENSG00000150676 Coiled-coil domain containing 83 11 85855101-85920021 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039707, HPA039882 Uncertain Nucleus
Plasma membrane
Cytosol Tissue enriched 132 testis: 63.3 parathyroid gland: 0.4 -RGS18 RGS13 ENSG00000150681 Regulator of G-protein signaling 18 1 192158457-192185815 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028727, HPA045780 Uncertain Uncertain Golgi apparatus Tissue enhanced 0 spleen: 35.5 appendix: 19.7 -PRSS23 SIG13, SPUVE ENSG00000150687 Protease, serine, 23 11 86791059-86952910 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030591 Uncertain Expressed in all cervix: 394.9 -MTMR12 3-PAP, 3PAP, FLJ20476, KIAA1682, PIP3AP ENSG00000150712 Myotubularin related protein 12 5 32226994-32313009 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051333 Supported Expressed in all parathyroid gland: 41.8 -PPP1R1C Inhibitor-1-like ENSG00000150722 Protein phosphatase 1, regulatory (inhibitor) subunit 1C 2 181954241-182131398 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055043 Approved Nucleus
Nucleoli
Golgi apparatus Tissue enriched 9 heart muscle: 13.0 prostate: 1.5 -C11orf53 MGC50104 ENSG00000150750 Chromosome 11 open reading frame 53 11 111255982-111286401 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056128 Uncertain Tissue enhanced 0 testis: 4.2 gallbladder: 2.1 -CCT5 KIAA0098 ENSG00000150753 Chaperonin containing TCP1, subunit 5 (epsilon) 5 10249921-10266412 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002238, HPA005958, CAB006271 Supported Supported Nucleoli
Cytosol Expressed in all testis: 190.1 -FAM173B ENSG00000150756 Family with sequence similarity 173, member B 5 10226330-10249897 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA074513 Approved Nucleus
Vesicles Expressed in all parathyroid gland: 25.7 -DOCK1 ced5, DOCK180 ENSG00000150760 Dedicator of cytokinesis 1 10 126905409-127452517 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004378, HPA048692, HPA053277 Approved Validated Nucleus Mixed parathyroid gland: 64.7 -DIXDC1 Dixin, KIAA1735 ENSG00000150764 DIX domain containing 1 11 111927144-112022584 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039424, HPA039658 Validated Cytosol Mixed seminal vesicle: 49.1 -DLAT DLTA, PDC-E2 ENSG00000150768 Dihydrolipoamide S-acetyltransferase 11 112024814-112064390 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003782, HPA040786, HPA062766 Supported Validated Mitochondria Expressed in all parathyroid gland: 31.8 -PIH1D2 ENSG00000150773 PIH1 domain containing 2 11 112064010-112074274 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039496 Uncertain Nucleoplasm
Cytosol Group enriched 7 fallopian tube: 34.6;testis: 125.8 thyroid gland: 11.6 -C11orf57 FLJ10726 ENSG00000150776 Chromosome 11 open reading frame 57 11 112074086-112085150 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039493, HPA039892 Approved Supported Cytosol Expressed in all thyroid gland: 27.2 -TIMM8B DDP2, FLJ21744, MGC102866, MGC117373, TIM8B ENSG00000150779 Translocase of inner mitochondrial membrane 8 homolog B (yeast) 11 112084800-112086798 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041173 Supported Expressed in all adrenal gland: 39.5 -IL18 IGIF, IL-18, IL-1g, IL1F4 ENSG00000150782 Interleukin 18 11 112143251-112164117 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003980, CAB007772 Supported Approved Nucleus
Golgi apparatus
Cytosol Tissue enhanced 0 esophagus: 133.6;skin: 171.9 lymph node: 73.1 -TEX12 ENSG00000150783 Testis expressed 12 11 112167372-112172559 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038289, HPA038290 Supported Tissue enriched 38 testis: 32.4 skin: 0.8 -PTS PTPS ENSG00000150787 6-pyruvoyltetrahydropterin synthase 11 112226365-112269955 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001481 Uncertain Approved Cytosol Expressed in all adrenal gland: 67.2 -PIP4K2A PIP5K2A, PIP5KIIA, PIP5KIIalpha ENSG00000150867 Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 10 22534849-22714555 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065440, HPA068771 Supported Approved Golgi apparatus
Plasma membrane
Cytosol Expressed in all cerebral cortex: 144.6 -C2orf50 FLJ25143 ENSG00000150873 Chromosome 2 open reading frame 50 2 11133053-11146790 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA062894 Supported Tissue enriched 9 fallopian tube: 22.4 cerebral cortex: 2.3 -FREM2 DKFZp686J0811 ENSG00000150893 FRAS1 related extracellular matrix protein 2 13 38687129-38887131 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028831 Uncertain Approved Cytosol Tissue enhanced 0 kidney: 8.2;thyroid gland: 8.2 lung: 3.3 -FOXO1 FKH1, FKHR, FOXO1A ENSG00000150907 Forkhead box O1 13 40555667-40666597 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001252, CAB022326 Approved Approved Supported Nucleoplasm
Cytosol Expressed in all ovary: 80.5 -CRIM1 S52 ENSG00000150938 Cysteine rich transmembrane BMP regulator 1 (chordin-like) 2 36355926-36551135 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000556 Approved Expressed in all placenta: 238.1 -SEC24D KIAA0755 ENSG00000150961 SEC24 homolog D, COPII coat complex component 4 118722823-118838683 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041626, HPA053486 Approved Approved Vesicles Mixed cervix: 76.3 -ABCB9 EST122234 ENSG00000150967 ATP-binding cassette, sub-family B (MDR/TAP), member 9 12 122920951-122981649 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033052, HPA035113, HPA035114 Approved Supported Vesicles Tissue enhanced 0 testis: 23.9 cerebral cortex: 12.1 -RILPL2 FLJ30380, FLJ32372, MGC7036 ENSG00000150977 Rab interacting lysosomal protein-like 2 12 123410683-123436717 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028958 Uncertain Supported Cytosol Mixed bone marrow: 21.6 -DHX37 DDX37, KIAA1517, MGC2695, MGC4322 ENSG00000150990 DEAH (Asp-Glu-Ala-His) box polypeptide 37 12 124946825-124989122 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047607 Approved Approved Nuclear membrane Mixed bone marrow: 10.0 -UBC ENSG00000150991 Ubiquitin C 12 124911604-124917368 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB000362, CAB005419, HPA041344, HPA049132 Supported Approved Nuclear speckles Expressed in all testis: 1956.0 -ITPR1 ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29 ENSG00000150995 Inositol 1,4,5-trisphosphate receptor, type 1 3 4493348-4847840 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014765, HPA016487 Approved Approved Vesicles Tissue enhanced 0 parathyroid gland: 104.9 thyroid gland: 47.2 -TKTL2 DKFZP434L1717, FLJ32975 ENSG00000151005 Transketolase-like 2 4 163471093-163473746 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 483 testis: 103.2 spleen: 0.2 -PRSS53 POL3S ENSG00000151006 Protease, serine, 53 16 31083425-31089628 Enzymes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA034955, HPA034956 Uncertain Tissue enhanced 0 skin: 1.1 spleen: 0.4 -SLC7A11 xCT ENSG00000151012 Solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 4 138164097-138242349 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064215 Approved Vesicles Tissue enhanced 0 cerebral cortex: 22.5 epididymis: 8.2 -NOCT Ccr4c, CCR4L, CCRN4L, NOC ENSG00000151014 Nocturnin 4 139015789-139045939 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA012287, HPA053714 Uncertain Supported Nucleoplasm
Nuclear bodies
Cytosol Tissue enhanced 0 bone marrow: 21.2 gallbladder: 8.4 -ENKUR C10orf63, CFAP106, enkurin, MGC26778 ENSG00000151023 Enkurin, TRPC channel interacting protein 10 24981979-25062279 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037593, HPA037594, HPA061503 Supported Tissue enhanced 0 fallopian tube: 68.9 cerebral cortex: 15.2 -GPR158 KIAA1136 ENSG00000151025 G protein-coupled receptor 158 10 25175062-25602226 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013185 Uncertain Approved Cytosol Tissue enriched 17 cerebral cortex: 17.9 testis: 1.0 -LYZL2 ENSG00000151033 Lysozyme-like 2 10 30611779-30629762 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 668 testis: 66.7 adipose tissue: 0.0 -CACNA2D4 ENSG00000151062 Calcium channel, voltage-dependent, alpha 2/delta subunit 4 12 1791957-1918836 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031952 Approved Not detected testis: 0.8 -DCP1B FLJ31638 ENSG00000151065 Decapping mRNA 1B 12 1946054-2004535 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039709, HPA058778 Approved Supported Vesicles
Cytosol Expressed in all testis: 36.6 -CACNA1C CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS ENSG00000151067 Calcium channel, voltage-dependent, L type, alpha 1C subunit 12 1970786-2697950 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039796 Supported Tissue enhanced 0 smooth muscle: 30.9 endometrium: 26.2 -KCNA6 ENSG00000151079 Potassium voltage-gated channel subfamily A member 6 12 4809176-4813412 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level No evidence Evidence at transcript level CAB011539, HPA014418 Approved Not detected lymph node: 0.1 -THRB ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2 ENSG00000151090 Thyroid hormone receptor, beta 3 24117160-24495282 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002008, CAB002009, HPA061035 Approved Supported Nuclear bodies Mixed cerebral cortex: 36.4 -NGLY1 FLJ11005, PNG1 ENSG00000151092 N-glycanase 1 3 25718944-25790039 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036825 Approved Expressed in all testis: 115.4 -OXSM FASN2D, FLJ20604, KS ENSG00000151093 3-oxoacyl-ACP synthase, mitochondrial 3 25782917-25794534 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021293, HPA021300, HPA021337 Supported Approved Mitochondria
Cytosol Expressed in all testis: 17.3 -UEVLD Attp, UEV3 ENSG00000151116 UEV and lactate/malate dehyrogenase domains 11 18529609-18588747 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047134 Approved Approved Nucleus
Cytosol Expressed in all parathyroid gland: 21.5 -TMEM86A FLJ90119 ENSG00000151117 Transmembrane protein 86A 11 18693122-18704785 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057119 Uncertain Mixed skin: 13.3 -C12orf45 MGC40397 ENSG00000151131 Chromosome 12 open reading frame 45 12 104986310-105049737 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038722 Uncertain Approved Nucleoplasm
Nuclear membrane Expressed in all thyroid gland: 25.8 -TMEM263 C12orf23, MGC17943 ENSG00000151135 Transmembrane protein 263 12 106955719-106978778 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042339 Uncertain Expressed in all cervix: 63.4 -BTBD11 ABTB2B, FLJ33957 ENSG00000151136 BTB (POZ) domain containing 11 12 107318413-107659642 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055898 Approved Nucleoplasm Tissue enhanced 0 parathyroid gland: 128.0 thyroid gland: 31.6 -UBE3B ENSG00000151148 Ubiquitin protein ligase E3B 12 109477402-109536705 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041012 Approved Approved Nuclear speckles
Mitochondria Expressed in all parathyroid gland: 33.4 -ANK3 ENSG00000151150 Ankyrin 3, node of Ranvier (ankyrin G) 10 60026298-60733490 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013249, CAB015179, HPA038455, HPA055643 Approved Approved Plasma membrane Expressed in all parathyroid gland: 284.5 -IPMK ENSG00000151151 Inositol polyphosphate multikinase 10 58191517-58267934 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037837, HPA057542 Uncertain Validated Nucleus Mixed parathyroid gland: 27.9 -RAD9B FLJ40346 ENSG00000151164 RAD9 checkpoint clamp component B 12 110501655-110532086 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040643 Approved Tissue enriched 32 testis: 20.4 ovary: 0.6 -PLBD2 p76 ENSG00000151176 Phospholipase B domain containing 2 12 113358566-113391625 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017163 Approved Expressed in all adrenal gland: 109.8 -DLG5 KIAA0583, P-dlg ENSG00000151208 Discs, large homolog 5 (Drosophila) 10 77790791-77926526 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001746 Supported Cell Junctions Mixed parathyroid gland: 33.2 -MAT1A MAT, MATA1, SAMS, SAMS1 ENSG00000151224 Methionine adenosyltransferase I, alpha 10 80271820-80289684 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048627 Supported Tissue enriched 10 liver: 689.4 epididymis: 67.2 -SLC2A13 HMIT ENSG00000151229 Solute carrier family 2 (facilitated glucose transporter), member 13 12 39755021-40106089 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006584 Approved Approved Nuclear membrane Tissue enhanced 0 cerebral cortex: 49.5;parathyroid gland: 73.3 cervix: 20.3 -GXYLT1 FLJ43151, GLT8D3 ENSG00000151233 Glucoside xylosyltransferase 1 12 42081845-42144879 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed testis: 17.8 -TWF1 A6, PTK9 ENSG00000151239 Twinfilin actin binding protein 1 12 43793723-43806375 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018116 Approved Validated Cytosol Expressed in all thyroid gland: 119.1 -DIP2C KIAA0934 ENSG00000151240 Disco-interacting protein 2 homolog C 10 274190-689668 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030264, HPA059325 Approved Approved Nucleoplasm
Vesicles
Cytosol Mixed cerebral cortex: 23.5 -EIF4E EIF4E1, EIF4EL1, EIF4F ENSG00000151247 Eukaryotic translation initiation factor 4E 4 98871684-98930637 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004077, CAB016316, HPA051311 Supported Validated Cytosol
Cytoplasmic bodies Expressed in all testis: 103.0 -MAGI1 AIP3, BAIAP1, BAP1, MAGI-1, TNRC19, WWP3 ENSG00000151276 Membrane associated guanylate kinase, WW and PDZ domain containing 1 3 65353525-66038834 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031851, HPA031852, HPA031853 Approved Validated Nucleoplasm
Cell Junctions Mixed thyroid gland: 18.8 -TEX30 C13orf27 ENSG00000151287 Testis expressed 30 13 102765990-102773811 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA053545 Supported Group enriched 7 epididymis: 87.5;testis: 223.0 placenta: 22.2 -CSNK1G3 ENSG00000151292 Casein kinase 1, gamma 3 5 123512099-123617045 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027010 Approved Expressed in all testis: 28.2 -SRFBP1 BUD22, FLJ25286, p49, Rlb1, STRAP ENSG00000151304 Serum response factor binding protein 1 5 121961961-122075570 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042737, HPA058150 Approved Supported Nucleus
Nucleoli fibrillar center
Vesicles Mixed thyroid gland: 13.9 -AKAP6 ADAP6, AKAP100, KIAA0311, mAKAP, PRKA6 ENSG00000151320 A kinase (PRKA) anchor protein 6 14 32329273-32837681 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001983, HPA048741 Supported Tissue enhanced 0 cerebral cortex: 49.1;heart muscle: 37.3 skeletal muscle: 16.6 -NPAS3 bHLHe12, MOP6, PASD6 ENSG00000151322 Neuronal PAS domain protein 3 14 32934933-33804176 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA002892 Approved Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 25.0 cervix: 10.0 -FAM177A1 C14orf24 ENSG00000151327 Family with sequence similarity 177, member A1 14 35044907-35113130 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053222, HPA055440 Uncertain Approved Nucleoplasm
Vesicles Expressed in all prostate: 102.4 -MBIP ENSG00000151332 MAP3K12 binding inhibitory protein 1 14 36298558-36320676 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003388 Supported Supported Nucleus
Nucleoli
Cytosol Expressed in all thyroid gland: 135.8 -MIPOL1 ENSG00000151338 Mirror-image polydactyly 1 14 37197913-37552361 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002893, HPA050179 Approved Approved Cytosol Mixed testis: 13.8 -EXT2 SOTV ENSG00000151348 Exostosin glycosyltransferase 2 11 44095549-44245429 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA078409 Supported Golgi apparatus Expressed in all placenta: 89.9 -TMEM18 DKFZp434C1714 ENSG00000151353 Transmembrane protein 18 2 667335-677439 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040233 Approved Approved Mitochondria Expressed in all ovary: 43.9 -ALLC ALC ENSG00000151360 Allantoicase 2 3658195-3702671 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 21 testis: 24.1 gallbladder: 1.1 -KCTD14 MGC2376 ENSG00000151364 Potassium channel tetramerization domain containing 14 11 78015715-78046191 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041118, HPA042181 Supported Mixed seminal vesicle: 26.7 -THRSP Lpgp, LPGP1, S14, SPOT14, THRP ENSG00000151365 Thyroid hormone responsive 11 78063861-78068351 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA040642 Approved Approved Nucleoplasm Tissue enhanced 0 adipose tissue: 231.3;liver: 182.4 breast: 43.2 -NDUFC2 B14.5b, HLC-1 ENSG00000151366 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 11 78068304-78080219 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038873, HPA056195 Approved Supported Mitochondria Expressed in all thyroid gland: 369.3 -ME3 ENSG00000151376 Malic enzyme 3, NADP(+)-dependent, mitochondrial 11 86441108-86672636 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038473 Approved Expressed in all parathyroid gland: 39.0 -MSGN1 pMesogenin1 ENSG00000151379 Mesogenin 1 2 17816496-17817101 Predicted intracellular proteins, Transcription factors No evidence No evidence No evidence Not detected esophagus: 0.4 -ADAMTS12 ENSG00000151388 ADAM metallopeptidase with thrombospondin type 1 motif, 12 5 33523535-33892192 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035973 Uncertain Mixed adipose tissue: 9.7 -NUBPL C14orf127, FLJ12660, huInd1, IND1 ENSG00000151413 Nucleotide binding protein-like 14 31489956-31861224 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029203 Approved Approved Mitochondria Expressed in all breast: 30.3 -NEK7 ENSG00000151414 NIMA-related kinase 7 1 198156963-198322420 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015520, HPA018193 Approved Supported Nucleoplasm Expressed in all heart muscle: 88.6 -ATP6V1G3 ATP6G3, Vma10 ENSG00000151418 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 1 198523222-198540945 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028701 Supported Tissue enriched 11 kidney: 21.1 epididymis: 1.9 -FER PPP1R74, TYK3 ENSG00000151422 Fer (fps/fes related) tyrosine kinase 5 108747822-109196841 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007641, CAB022464 Approved Supported Cytosol Mixed parathyroid gland: 19.2 -VIPAS39 C14orf133, hSPE-39, SPE-39, SPE39, VIPAR, VPS16B ENSG00000151445 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 14 77426675-77457952 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003589, HPA003593 Approved Expressed in all testis: 29.1 -ANKRD50 KIAA1223 ENSG00000151458 Ankyrin repeat domain 50 4 124664052-124712732 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044008 Approved Approved Nucleoplasm
Cytosol Mixed testis: 27.6 -UPF2 DKFZP434D222, KIAA1408, RENT2, smg-3 ENSG00000151461 UPF2 regulator of nonsense transcripts homolog (yeast) 10 11920022-12043170 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067008 Supported Cytosol
Cytoplasmic bodies Expressed in all testis: 35.9 -CDC123 C10orf7, D123 ENSG00000151465 Cell division cycle 123 10 12195965-12250589 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037830 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all lymph node: 66.2 -SCLT1 FLJ30655, hCAP-1A ENSG00000151466 Sodium channel and clathrin linker 1 4 128864921-129093607 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036560, HPA036561 Approved Supported Microtubules
Cytosol Mixed spleen: 11.5 -CCDC3 DKFZp761F241 ENSG00000151468 Coiled-coil domain containing 3 10 12896625-13099652 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062425 Approved Nucleus
Cytosol Mixed skin: 158.8 -C4orf33 FLJ33703 ENSG00000151470 Chromosome 4 open reading frame 33 4 129093317-129116640 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061199 Uncertain Approved Nuclear bodies
Golgi apparatus Expressed in all thyroid gland: 28.1 -FRMD4A bA295P9.4, FLJ10210, FRMD4, KIAA1294 ENSG00000151474 FERM domain containing 4A 10 13643706-14462142 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038449 Uncertain Approved Nucleus
Golgi apparatus Expressed in all spleen: 38.7 -SLC25A31 ANT4, DKFZP434N1235 ENSG00000151475 Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 4 127730378-127774299 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA015064, HPA016841, HPA046835, HPA071684 Uncertain Validated Mitochondria Tissue enriched 849 testis: 84.9 epididymis: 0.0 -PTPRO GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2 ENSG00000151490 Protein tyrosine phosphatase, receptor type, O 12 15322397-15597399 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034525 Supported Tissue enhanced 0 rectum: 33.5 cerebral cortex: 21.8 -EPS8 ENSG00000151491 Epidermal growth factor receptor pathway substrate 8 12 15620158-15882329 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003897 Approved Approved Golgi apparatus Mixed gallbladder: 88.4 -ACAD8 ENSG00000151498 Acyl-CoA dehydrogenase family, member 8 11 134253495-134265855 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040689, HPA043903 Supported Expressed in all thyroid gland: 43.1 -THYN1 THY28 ENSG00000151500 Thymocyte nuclear protein 1 11 134248279-134253370 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038732, HPA038733 Supported Supported Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all epididymis: 90.7 -VPS26B MGC10485, Pep8b ENSG00000151502 VPS26 retromer complex component B 11 134224645-134247792 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038172 Uncertain Expressed in all cerebral cortex: 60.5 -NCAPD3 CAP-D3, FLJ42888, hCAP-D3, hcp-6, hHCP-6, KIAA0056 ENSG00000151503 Non-SMC condensin II complex, subunit D3 11 134150119-134225454 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040286 Supported Nucleoplasm Tissue enriched 10 prostate: 175.5 testis: 17.2 -VTI1A MVti1, Vti1-rp2, Vti1a ENSG00000151532 Vesicle transport through interaction with t-SNAREs 1A 10 112446998-112818744 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054108 Supported Supported Golgi apparatus
Vesicles Mixed parathyroid gland: 12.1 -QDPR DHPR, PKU2, SDR33C1 ENSG00000151552 Quinoid dihydropteridine reductase 4 17460261-17512234 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058951, HPA065649 Supported Approved Mitochondria Expressed in all cerebral cortex: 226.9 -FAM160B1 bA106M7.3, KIAA1600 ENSG00000151553 Family with sequence similarity 160, member B1 10 114821744-114899832 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043624 Uncertain Approved Nuclear speckles
Cytosol Expressed in all testis: 34.2 -ANO4 FLJ34221, FLJ34272, FLJ35277, TMEM16D ENSG00000151572 Anoctamin 4 12 100717526-101128641 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053412 Uncertain Group enriched 6 adrenal gland: 17.6;cerebral cortex: 10.0;cervix, uterine: 12.5;endometrium: 8.3;ovary: 10.9;prostate: 10.9;seminal vesicle: 11.3 testis: 2.0 -TEX9 ENSG00000151575 Testis expressed 9 15 56244009-56445997 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039415 Uncertain Approved Plasma membrane
Cytosol Mixed fallopian tube: 44.1 -QTRTD1 FLJ12960 ENSG00000151576 Queuine tRNA-ribosyltransferase domain containing 1 3 114005833-114088422 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036827, HPA036828 Uncertain Approved Nucleoplasm
Intermediate filaments Expressed in all spleen: 16.6 -DRD3 ENSG00000151577 Dopamine receptor D3 3 114128652-114199407 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 13 testis: 1.3 lymph node: 0.1 -MMAA cblA ENSG00000151611 Methylmalonic aciduria (cobalamin deficiency) cblA type 4 145618263-145660035 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037361 Approved Approved Cytosol Mixed liver: 12.3 -ZNF827 ENSG00000151612 Zinc finger protein 827 4 145757627-145938635 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021166 Uncertain Approved Nucleoplasm Mixed prostate: 36.1 -POU4F2 Brn-3b, BRN3B ENSG00000151615 POU class 4 homeobox 2 4 146638893-146642474 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 18 testis: 1.8 epididymis: 0.0 -EDNRA ENSG00000151617 Endothelin receptor type A 4 147480917-147544954 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013774, CAB018957 Uncertain Tissue enhanced 0 seminal vesicle: 145.4 cervix: 82.6 -NR3C2 MLR, MR ENSG00000151623 Nuclear receptor subfamily 3, group C, member 2 4 148078762-148444698 Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009155, HPA074979 Supported Approved Nucleoplasm Mixed thyroid gland: 32.1 -AKR1C2 BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD ENSG00000151632 Aldo-keto reductase family 1, member C2 10 4922564-5135226 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB047304, HPA068265 Approved Approved Nucleus
Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Group enriched 5 adipose tissue: 352.3;breast: 122.0;esophagus: 118.4;gallbladder: 189.9;liver: 186.5;stomach: 138.5;urinary bladder: 186.3 duodenum: 33.7 -DPYSL4 DRP-4, ULIP4 ENSG00000151640 Dihydropyrimidinase-like 4 10 132186900-132205776 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049066 Approved Approved Vesicles
Mitochondria Tissue enhanced 0 cerebral cortex: 30.1 testis: 6.8 -VENTX HPX42B, VENTX2 ENSG00000151650 VENT homeobox 10 133237404-133241929 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050955 Uncertain Uncertain Nucleoli fibrillar center
Cytosol Mixed appendix: 4.9 -ADAM8 CD156, CD156a, MS2 ENSG00000151651 ADAM metallopeptidase domain 8 10 133262403-133276868 CD markers, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064637 Approved Tissue enhanced 0 bone marrow: 43.9;spleen: 33.5 appendix: 30.9 -ITIH2 H2P ENSG00000151655 Inter-alpha-trypsin inhibitor heavy chain 2 10 7703269-7749520 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059150 Supported Approved Golgi apparatus Tissue enriched 207 liver: 1092.2 cerebral cortex: 5.2 -KIN KIN17, Rts2 ENSG00000151657 Kin17 DNA and RNA binding protein 10 7750962-7787981 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016339, HPA038700 Validated Nucleus Mixed endometrium: 5.6 -PIGF ENSG00000151665 Phosphatidylinositol glycan anchor biosynthesis, class F 2 46580937-46617119 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051389 Uncertain Expressed in all testis: 47.8 -ANKAR FLJ25415 ENSG00000151687 Ankyrin and armadillo repeat containing 2 189674290-189761193 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036168 Uncertain Approved Nucleus
Microtubule organizing center Tissue enriched 7 testis: 10.2 parathyroid gland: 1.4 -INPP1 ENSG00000151689 Inositol polyphosphate-1-phosphatase 2 190343470-190371665 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036698, HPA036699 Supported Uncertain Vesicles
Microtubule organizing center Expressed in all testis: 73.2 -MFSD6 FLJ20160 ENSG00000151690 Major facilitator superfamily domain containing 6 2 190408355-190509205 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022274 Approved Approved Nucleoplasm
Actin filaments
Cytosol Expressed in all cerebral cortex: 79.2 -RNF144A KIAA0161, RNF144, UBCE7IP4 ENSG00000151692 Ring finger protein 144A 2 6917392-7068286 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049939 Approved Approved Vesicles Mixed endometrium: 42.8 -ASAP2 CENTB3, DDEF2, KIAA0400, PAP, SHAG1 ENSG00000151693 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2 9206765-9405683 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018615 Approved Supported Cytosol Tissue enhanced 0 testis: 73.3 thyroid gland: 32.0 -ADAM17 CD156B, cSVP, TACE ENSG00000151694 ADAM metallopeptidase domain 17 2 9488486-9555792 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010738, CAB025906, HPA051575 Approved Supported Cytosol Expressed in all placenta: 33.9 -FLI1 EWSR2, SIC-1 ENSG00000151702 Fli-1 proto-oncogene, ETS transcription factor 11 128686535-128813267 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA073099 Supported Nucleus
Nuclear bodies Tissue enhanced 0 spleen: 48.1 placenta: 16.2 -KCNJ1 Kir1.1, ROMK1 ENSG00000151704 Potassium channel, inwardly rectifying subfamily J, member 1 11 128836315-128867373 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level HPA026962 Supported Tissue enriched 118 kidney: 209.0 epididymis: 1.7 -TMEM45B BC016153, FLJ40787 ENSG00000151715 Transmembrane protein 45B 11 129815819-129860003 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015878 Approved Uncertain Nucleoplasm
Cytosol Tissue enhanced 0 duodenum: 140.0;small intestine: 141.9 rectum: 104.8 -WWC2 BOMB, FLJ22029 ENSG00000151718 WW and C2 domain containing 2 4 183099293-183320777 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044005 Uncertain Approved Microtubules Mixed lung: 42.5 -CENPU CENP-50, CENP-U, KLIP1, MLF1IP, PBIP1 ENSG00000151725 Centromere protein U 4 184694618-184734133 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022048 Approved Supported Nucleus
Microtubule organizing center Tissue enhanced 0 bone marrow: 45.7;testis: 67.2 lymph node: 25.5 -ACSL1 ACS1, FACL1, FACL2, LACS, LACS1, LACS2 ENSG00000151726 Acyl-CoA synthetase long-chain family member 1 4 184755595-184826818 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011316, HPA011964 Supported Supported Nucleus
Mitochondria Expressed in all adipose tissue: 820.6 -SLC25A4 ANT1, PEO2, PEO3, T1 ENSG00000151729 Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 4 185143241-185150382 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046835, HPA071684 Approved Supported Mitochondria Tissue enhanced 0 heart muscle: 119.0;skeletal muscle: 66.2 cerebral cortex: 38.2 -AMN1 ENSG00000151743 Antagonist of mitotic exit network 1 homolog 12 31671137-31729174 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046157, HPA062290 Uncertain Approved Centrosome Expressed in all testis: 99.3 -BICD1 ENSG00000151746 Bicaudal D homolog 1 (Drosophila) 12 32106835-32383633 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041309 Uncertain Approved Vesicles Mixed ovary: 28.9 -SAV1 salvador, WW45, WWP4 ENSG00000151748 Salvador family WW domain containing protein 1 14 50632058-50668331 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001808 Approved Supported Cytosol Expressed in all thyroid gland: 58.1 -CCDC122 FLJ31846 ENSG00000151773 Coiled-coil domain containing 122 13 43823909-43879727 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB034233, HPA054995, HPA061456 Approved Approved Nucleus
Vesicles Mixed thyroid gland: 7.8 -SERP2 bA269C23.1, C13orf21 ENSG00000151778 Stress-associated endoplasmic reticulum protein family member 2 13 44373665-44397714 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038970 Uncertain Approved Endoplasmic reticulum Tissue enhanced 0 cerebral cortex: 52.9;testis: 23.7 epididymis: 11.3 -NBAS NAG ENSG00000151779 Neuroblastoma amplified sequence 2 15166909-15561330 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036817 Approved Approved Nuclear membrane
Nucleoli
Golgi apparatus Expressed in all testis: 37.4 -ZNF385D FLJ22419, ZNF659 ENSG00000151789 Zinc finger protein 385D 3 21412222-22373321 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036190 Uncertain Tissue enhanced 0 cerebral cortex: 4.8 adipose tissue: 3.0 -TDO2 TDO, TPH2 ENSG00000151790 Tryptophan 2,3-dioxygenase 4 155854738-155920406 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039611 Uncertain Uncertain Plasma membrane
Cytosol Tissue enriched 17 liver: 277.5 appendix: 16.2 -GUF1 FLJ13220 ENSG00000151806 GUF1 homolog, GTPase 4 44678427-44700926 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003934, HPA024222 Approved Approved Nucleus
Mitochondria Mixed cerebral cortex: 13.5 -SLC35F4 C14orf36, FLJ37712 ENSG00000151812 Solute carrier family 35, member F4 14 57563922-57982194 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043853 Uncertain Approved Nucleoli fibrillar center Tissue enhanced 0 prostate: 1.9;seminal vesicle: 4.9;testis: 1.8 thyroid gland: 1.0 -GABRA2 ENSG00000151834 Gamma-aminobutyric acid (GABA) A receptor, alpha 2 4 46248427-46475230 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 6 cerebral cortex: 74.5 epididymis: 13.3 -SACS ARSACS, DKFZp686B15167, DNAJC29, KIAA0730, PPP1R138, SPAX6 ENSG00000151835 Sacsin molecular chaperone 13 23328823-23433728 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017714 Uncertain Tissue enhanced 0 parathyroid gland: 31.6 cerebral cortex: 16.0 -CCDC175 C14orf38 ENSG00000151838 Coiled-coil domain containing 175 14 59504539-59576831 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA004200 Uncertain Approved Nucleus
Nucleoli
Cytosol Tissue enriched 8 testis: 4.0 fallopian tube: 0.4 -PABPC3 PABP3, PABPL3, tPABP ENSG00000151846 Poly(A) binding protein, cytoplasmic 3 13 25095868-25099254 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045423, HPA067156 Approved Approved Cytosol Tissue enriched 149 testis: 60.2 cerebral cortex: 0.4 -CENPJ BM032, CPAP, LAP, LIP1, MCPH6, Sas-4, SASS4, SCKL4 ENSG00000151849 Centromere protein J 13 24882284-24922889 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060426 Approved Nucleoplasm
Plasma membrane
Centrosome Tissue enhanced 0 testis: 43.4 thyroid gland: 20.5 -FBXO4 FBX4 ENSG00000151876 F-box protein 4 5 41925254-41941743 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003362 Approved Nucleus Expressed in all thyroid gland: 20.9 -C5orf28 FLJ21657 ENSG00000151881 Chromosome 5 open reading frame 28 5 43444252-43483893 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059946 Approved Nucleoplasm Expressed in all thyroid gland: 64.8 -CCL28 CCK1, MEC, SCYA28 ENSG00000151882 Chemokine (C-C motif) ligand 28 5 43376645-43412391 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 breast: 71.4;salivary gland: 126.7 thyroid gland: 38.0 -PARP8 FLJ21308, pART16 ENSG00000151883 Poly (ADP-ribose) polymerase family, member 8 5 50665899-50846522 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA049183 Approved Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 72.0 -GFRA1 GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1 ENSG00000151892 GDNF family receptor alpha 1 10 116056925-116273467 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043829 Uncertain Approved Nucleoplasm
Golgi apparatus Mixed breast: 30.1 -CACUL1 C10orf46, CAC1, FLJ40409, MGC33215 ENSG00000151893 CDK2-associated, cullin domain 1 10 118674167-118755249 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050611 Uncertain Nucleoplasm Expressed in all parathyroid gland: 12.0 -DST BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2 ENSG00000151914 Dystonin 6 56457987-56954628 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030200 Uncertain Approved Nucleus
Microtubules
Cytosol Expressed in all skin: 192.5 -BEND6 bA203B9.1, C6orf65, FLJ30162 ENSG00000151917 BEN domain containing 6 6 56955126-57027342 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052973 Approved Nucleus
Plasma membrane Tissue enriched 6 cerebral cortex: 39.3 cervix: 6.7 -TIAL1 TIAR ENSG00000151923 TIA1 cytotoxic granule-associated RNA binding protein-like 1 10 119571802-119597029 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060962 Approved Nucleus
Vesicles Expressed in all parathyroid gland: 84.9 -BAG3 ENSG00000151929 BCL2-associated athanogene 3 10 119651370-119677819 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018493, HPA020586 Supported Validated Plasma membrane
Cytosol Expressed in all skeletal muscle: 98.2 -GLT1D1 FLJ31978 ENSG00000151948 Glycosyltransferase 1 domain containing 1 12 128853427-128984968 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039051, HPA039052 Validated Cytosol Tissue enhanced 0 cerebral cortex: 22.5;testis: 28.1 bone marrow: 18.6 -TMEM132D KIAA1944, MOLT, PPP1R153 ENSG00000151952 Transmembrane protein 132D 12 129071725-129903666 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA010739 Approved Tissue enriched 9 cerebral cortex: 12.8 testis: 1.4 -RBM46 CT68, MGC27016 ENSG00000151962 RNA binding motif protein 46 4 154781213-154828813 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 59 testis: 50.0 thyroid gland: 0.8 -SCHIP1 SCHIP-1 ENSG00000151967 Schwannomin interacting protein 1 3 159839861-159897360 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA003243 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 103.2;heart muscle: 52.0 skeletal muscle: 25.5 -MCHR2 GPR145, MCH2, MCH2R, SLT ENSG00000152034 Melanin-concentrating hormone receptor 2 6 99919910-99994247 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 53 cerebral cortex: 8.6;testis: 6.2 colon: 0.1 -KCNE4 MiRP3 ENSG00000152049 Potassium channel, voltage gated subfamily E regulatory beta subunit 4 2 223051814-223198399 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011420 Approved Approved Nuclear bodies
Microtubules Tissue enhanced 0 smooth muscle: 53.5 endometrium: 33.4 -AP1S3 ENSG00000152056 Adaptor-related protein complex 1, sigma 3 subunit 2 223751686-223838027 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066782 Approved Supported Vesicles Tissue enhanced 0 epididymis: 53.9 thyroid gland: 23.7 -RABGAP1L FLJ38519, HHL, KIAA0471, TBC1D18 ENSG00000152061 RAB GTPase activating protein 1-like 1 174159410-174995308 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054695 Uncertain Approved Nucleoli
Cytosol Expressed in all heart muscle: 89.1 -CCDC74B DKFZp434E2321 ENSG00000152076 Coiled-coil domain containing 74B 2 130139287-130145134 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060727 Uncertain Vesicles Tissue enhanced 0 fallopian tube: 22.9;testis: 52.1 cervix: 13.9 -TMEM56 FLJ31842 ENSG00000152078 Transmembrane protein 56 1 95117338-95197607 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046762 Uncertain Approved Nuclear speckles Tissue enhanced 0 liver: 66.0 heart muscle: 16.1 -MZT2B FAM128B, FLJ14346, MOZART2B ENSG00000152082 Mitotic spindle organizing protein 2B 2 130181737-130190729 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051758, HPA052623 Approved Supported Centrosome
Cytosol Expressed in all testis: 81.9 -TUBA3E ENSG00000152086 Tubulin, alpha 3e 2 130191743-130198461 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039247, HPA043684, HPA063394 Uncertain Supported Microtubules Tissue enriched 30 testis: 74.2 heart muscle: 2.4 -ASTN1 ASTN ENSG00000152092 Astrotactin 1 1 176857302-177164973 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA074112 Approved Golgi apparatus
Vesicles Group enriched 6 adrenal gland: 19.7;cerebral cortex: 67.0 ovary: 7.4 -CFC1B ENSG00000152093 Cripto, FRL-1, cryptic family 1B 2 130521197-130528604 Predicted secreted proteins No evidence No evidence No evidence HPA041773 Uncertain Not detected prostate: 0.1 -FAM168B KIAA0280L ENSG00000152102 Family with sequence similarity 168, member B 2 131047876-131093460 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043778, HPA061659 Approved Expressed in all cerebral cortex: 112.9 -PTPN14 PEZ ENSG00000152104 Protein tyrosine phosphatase, non-receptor type 14 1 214348696-214552449 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011469, HPA053864, CAB069441 Uncertain Validated Nucleoplasm Mixed skin: 20.0 -MGAT5 GNT-V ENSG00000152127 Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 2 134119983-134454621 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA010919 Approved Mixed parathyroid gland: 32.0 -TMEM163 DKFZP566N034, SV31 ENSG00000152128 Transmembrane protein 163 2 134455759-134719000 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA007224 Uncertain Mixed lung: 21.5 -GPATCH11 CCDC75, CENP-Y, CENPY, FLJ38348 ENSG00000152133 G patch domain containing 11 2 37084451-37099244 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038231, HPA038232 Approved Supported Nucleus Mixed adipose tissue: 23.8 -HSPB8 CMT2L, E2IG1, H11, HSP22, HspB8 ENSG00000152137 Heat shock 22kDa protein 8 12 119178642-119221131 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015876 Approved Supported Cytosol Mixed parathyroid gland: 418.6 -GEMIN6 FLJ23459 ENSG00000152147 Gem (nuclear organelle) associated protein 6 2 38751534-38785000 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035726, HPA035727 Approved Supported Nucleoplasm
Nuclear bodies Mixed testis: 28.7 -TMEM178A MGC33926, TMEM178 ENSG00000152154 Transmembrane protein 178A 2 39664982-39717963 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052128, HPA058560 Uncertain Approved Nucleus
Vesicles Tissue enhanced 0 cerebral cortex: 55.6 kidney: 19.1 -POU4F1 BRN3A, RDC-1 ENSG00000152192 POU class 4 homeobox 1 13 78598362-78603560 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA068024 Supported Tissue enhanced 0 testis: 2.4 tonsil: 0.7 -RNF219 C13orf7, FLJ13449 ENSG00000152193 Ring finger protein 219 13 78614291-78659179 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034785, HPA034786 Supported Approved Nucleoplasm
Nuclear bodies
Cytosol Mixed testis: 27.2 -CYSLTR2 CysLT(2), CYSLT2R ENSG00000152207 Cysteinyl leukotriene receptor 2 13 48653711-48711226 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046528 Uncertain Tissue enhanced 0 placenta: 36.4;seminal vesicle: 24.8 spleen: 11.6 -GRID2 GluD2, GluR-delta-2 ENSG00000152208 Glutamate receptor, ionotropic, delta 2 4 92303622-93774556 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056253, HPA058538 Approved Tissue enriched 10 testis: 59.7 cerebral cortex: 5.9 -ARL11 ARLTS1, FLJ33930 ENSG00000152213 ADP-ribosylation factor-like 11 13 49628299-49633872 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040855, HPA040887 Uncertain Tissue enhanced 0 lymph node: 7.7 spleen: 6.4 -RIT2 RIBA, RIN ENSG00000152214 Ras-like without CAAX 2 18 42743227-43115691 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 cerebral cortex: 18.3 adrenal gland: 2.8 -SETBP1 KIAA0437, SEB ENSG00000152217 SET binding protein 1 18 44680173-45068510 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049022, HPA057259 Uncertain Supported Nucleus
Nuclear bodies
Cytosol Expressed in all seminal vesicle: 13.8 -ARL14EP ARF7EP, C11orf46, FLJ38968 ENSG00000152219 ADP-ribosylation factor-like 14 effector protein 11 30323051-30338227 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039634, HPA048127 Approved Approved Nucleus
Vesicles
Focal adhesion sites
Cytosol Expressed in all parathyroid gland: 52.5 -EPG5 hEPG5, KIAA1632 ENSG00000152223 Ectopic P-granules autophagy protein 5 homolog (C. elegans) 18 45847609-45967274 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA031689 Approved Approved Nuclear speckles Mixed parathyroid gland: 12.2 -PSTPIP2 ENSG00000152229 Proline-serine-threonine phosphatase interacting protein 2 18 45983536-46072272 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040923, HPA040944 Supported Approved Nucleus
Plasma membrane
Mitochondria Tissue enhanced 0 bone marrow: 47.3;spleen: 70.7 placenta: 17.3 -ATP5A1 ATP5A, ATP5AL2, ATPM, hATP1, OMR, ORM ENSG00000152234 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 18 46080248-46104334 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013067, HPA040622, HPA044202 Supported Supported Mitochondria Expressed in all parathyroid gland: 853.0 -HAUS1 CCDC5, FLJ40084, HEI-C, HsT1461 ENSG00000152240 HAUS augmin-like complex, subunit 1 18 46104332-46128333 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040601, HPA040652 Supported Supported Cytosol Expressed in all epididymis: 40.4 -C18orf25 ARKL1, MGC12909, RNF111L1 ENSG00000152242 Chromosome 18 open reading frame 25 18 46173553-46266991 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051314, HPA051899 Approved Approved Nucleoplasm
Cytosol Expressed in all esophagus: 39.0 -SPC25 AD024, MGC22228, SPBC25 ENSG00000152253 SPC25, NDC80 kinetochore complex component 2 168834132-168913371 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047144, HPA050544 Approved Validated Cytosol Mixed lymph node: 5.0 -G6PC2 IGRP ENSG00000152254 Glucose-6-phosphatase, catalytic, 2 2 168901240-168910000 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 13 pancreas: 2.9 testis: 0.2 -PDK1 ENSG00000152256 Pyruvate dehydrogenase kinase, isozyme 1 2 172555373-172608669 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017554, HPA027376, HPA059083 Approved Approved Nucleoli
Mitochondria Expressed in all testis: 22.3 -PTH PTH1 ENSG00000152266 Parathyroid hormone 11 13492055-13496181 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB000072, CAB023409, CAB026363, HPA048540 Supported Tissue enriched 24434 parathyroid gland: 58263.3 heart muscle: 2.3 -PDE3B HcGIP1 ENSG00000152270 Phosphodiesterase 3B, cGMP-inhibited 11 14643723-14872044 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056111 Supported Endoplasmic reticulum Tissue enhanced 0 adipose tissue: 65.3 lymph node: 17.4 -TCF7L1 TCF3 ENSG00000152284 Transcription factor 7-like 1 (T-cell specific, HMG-box) 2 85133410-85310388 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA071298 Supported Nucleoplasm
Cytosol Mixed endometrium: 22.8 -TGOLN2 TGN38, TGN46, TGN48, TGN51, TTGN2 ENSG00000152291 Trans-golgi network protein 2 2 85318020-85328425 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011489, HPA012609, HPA012723 Supported Validated Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 145.8 -SH2D6 FLJ35993 ENSG00000152292 SH2 domain containing 6 2 85418721-85437029 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053873 Uncertain Tissue enhanced 0 duodenum: 4.1;testis: 4.7;thyroid gland: 3.9 small intestine: 2.7 -KCNK13 K2p13.1, THIK-1, THIK1 ENSG00000152315 Potassium channel, two pore domain subfamily K, member 13 14 90061765-90185857 Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003514 Approved Approved Nuclear speckles
Cell Junctions Tissue enhanced 0 parathyroid gland: 14.3;testis: 14.4 kidney: 3.3 -UHMK1 KIS, Kist ENSG00000152332 U2AF homology motif (UHM) kinase 1 1 162497251-162529629 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071190 Supported Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 43.4 -ATG10 APG10L, DKFZP586I0418, FLJ13954 ENSG00000152348 Autophagy related 10 5 81972025-82276857 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044163 Approved Approved Nucleus
Nucleoli Mixed parathyroid gland: 21.9 -POC5 C5orf37, FLJ35779, hPOC5, MGC120442, MGC120443, MGC120444 ENSG00000152359 POC5 centriolar protein 5 75674124-75717481 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037509, HPA037510, HPA061521 Approved Approved Nucleus Mixed testis: 36.1 -SPOCK1 SPOCK, testican-1, TIC1 ENSG00000152377 Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 5 136975298-137598379 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007450, HPA026770 Uncertain Approved Vesicles Tissue enhanced 0 cerebral cortex: 209.7 prostate: 103.6 -FAM151B UNQ9217 ENSG00000152380 Family with sequence similarity 151, member B 5 80487969-80542563 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043805 Uncertain Approved Cytosol Mixed bone marrow: 2.8 -TADA1 ADA1, hADA1, HFI1, STAF42, TADA1L ENSG00000152382 Transcriptional adaptor 1 1 166856510-166876327 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028651 Approved Supported Nucleoplasm
Focal adhesion sites
Cytosol Expressed in all cerebral cortex: 23.9 -GUCY1A2 GC-SA2, GUC1A2 ENSG00000152402 Guanylate cyclase 1, soluble, alpha 2 11 106674012-107018524 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB009534 Uncertain Tissue enhanced 0 placenta: 25.4 endometrium: 21.0 -CWF19L2 FLJ32343 ENSG00000152404 CWF19-like 2, cell cycle control (S. pombe) 11 107326345-107457844 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038166 Uncertain Approved Nuclear speckles
Cytosol Expressed in all endometrium: 18.0 -JMY FLJ37870, WHAMM2 ENSG00000152409 Junction mediating and regulatory protein, p53 cofactor 5 79236189-79327215 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037508, HPA043308 Uncertain Uncertain Nucleoplasm Expressed in all parathyroid gland: 22.2 -HOMER1 HOMER-1B, SYN47, Ves-1 ENSG00000152413 Homer scaffolding protein 1 5 79372636-79514217 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004437, HPA036521, HPA036522 Supported Approved Cytosol Tissue enhanced 0 cerebral cortex: 49.0 thyroid gland: 25.0 -XRCC4 ENSG00000152422 X-ray repair complementing defective repair in Chinese hamster cells 4 5 83077498-83353787 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006801, HPA051538 Supported Supported Nucleus Mixed testis: 16.0 -BOLL BOULE ENSG00000152430 Boule-like RNA-binding protein 2 197726879-197786762 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA018678, HPA048813 Supported Tissue enriched 67 testis: 87.4 skeletal muscle: 1.3 -ZNF547 FLJ31100 ENSG00000152433 Zinc finger protein 547 19 57363477-57379565 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056001 Uncertain Mixed thyroid gland: 5.2 -ZNF773 MGC4728, ZNF419B ENSG00000152439 Zinc finger protein 773 19 57499915-57518404 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003152 Uncertain Approved Nucleus
Nucleoli fibrillar center Mixed parathyroid gland: 13.2 -ZNF776 FLJ38288 ENSG00000152443 Zinc finger protein 776 19 57746796-57758159 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA046653, HPA068553 Uncertain Approved Nucleus
Cytosol Mixed epididymis: 26.2 -ZNF256 BMZF-3 ENSG00000152454 Zinc finger protein 256 19 57940833-57947675 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA055390 Uncertain Supported Nucleus Mixed testis: 7.9 -SUV39H2 FLJ23414, KMT1B ENSG00000152455 Suppressor of variegation 3-9 homolog 2 (Drosophila) 10 14878820-14904315 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045901, HPA057554 Supported Approved Mitochondria Tissue enriched 12 testis: 72.5 placenta: 6.2 -DCLRE1C A-SCID, ARTEMIS, FLJ11360, SCIDA, SNM1C ENSG00000152457 DNA cross-link repair 1C 10 14897359-14954432 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069295 Supported Nucleoplasm
Golgi apparatus Mixed lymph node: 16.6 -OLAH FLJ11106, SAST, THEDC1 ENSG00000152463 Oleoyl-ACP hydrolase 10 15032227-15073852 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037947, HPA037948 Approved Tissue enriched 6 testis: 46.1 breast: 7.1 -RPP38 ENSG00000152464 Ribonuclease P/MRP 38kDa subunit 10 15097180-15139818 Enzymes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045128 Supported Nucleoli Expressed in all testis: 76.5 -NMT2 ENSG00000152465 N-myristoyltransferase 2 10 15102584-15168693 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001303 Approved Supported Golgi apparatus
Plasma membrane
Cytosol Expressed in all parathyroid gland: 39.2 -ZSCAN1 FLJ33779, ZNF915 ENSG00000152467 Zinc finger and SCAN domain containing 1 19 58034032-58054631 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA007938 Uncertain Approved Nucleoli Tissue enhanced 0 epididymis: 7.6 cerebral cortex: 5.3 -ZNF837 ENSG00000152475 Zinc finger protein 837 19 58367618-58381060 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042833 Uncertain Approved Nucleoli Mixed spleen: 1.4 -USP12 USP12L1 ENSG00000152484 Ubiquitin specific peptidase 12 13 27066142-27171896 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007288 Uncertain Expressed in all bone marrow: 45.8 -CCDC50 C3orf6, DFNA44, Ymer ENSG00000152492 Coiled-coil domain containing 50 3 191329077-191398670 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001336 Approved Supported Cytosol Expressed in all gallbladder: 49.4 -CAMK4 CaMK-GR ENSG00000152495 Calcium/calmodulin-dependent protein kinase IV 5 111223653-111494886 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004347, HPA011753, HPA017206 Approved Supported Nucleoplasm
Nucleoli fibrillar center Tissue enhanced 0 cerebral cortex: 16.6;testis: 16.9 lymph node: 9.9 -TRIM36 HAPRIN, RBCC728, RNF98 ENSG00000152503 Tripartite motif containing 36 5 115124762-115180546 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061321 Approved Nucleus
Cytosol Tissue enriched 16 testis: 312.6 cerebral cortex: 19.9 -ZFP36L2 BRF2, ERF2, RNF162C, TIS11D ENSG00000152518 ZFP36 ring finger protein-like 2 2 43222402-43226609 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047428 Approved Expressed in all thyroid gland: 273.3 -PAN3 ENSG00000152520 PAN3 poly(A) specific ribonuclease subunit 13 28138506-28295335 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028817 Approved Expressed in all spleen: 29.1 -PLEKHH2 KIAA2028, PLEKHH1L ENSG00000152527 Pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 2 43637273-43767987 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA077225 Supported Plasma membrane Mixed endometrium: 31.8 -PFKM PFK-1, PFKX, PPP1R122 ENSG00000152556 Phosphofructokinase, muscle 12 48105139-48146404 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002117 Approved Approved Endoplasmic reticulum Expressed in all skeletal muscle: 549.4 -TMEM123 KCT3, PORIMIN ENSG00000152558 Transmembrane protein 123 11 102396332-102470384 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB026001 Approved Cytosol Expressed in all thyroid gland: 573.7 -GRIA4 GluA4, GLUR4, GLURD ENSG00000152578 Glutamate receptor, ionotropic, AMPA 4 11 105609994-105982092 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 10 cerebral cortex: 73.4 adrenal gland: 7.4 -IGSF10 CMF608, FLJ25972 ENSG00000152580 Immunoglobulin superfamily, member 10 3 151425384-151458709 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012921 Uncertain Approved Nucleoplasm
Intermediate filaments Tissue enhanced 0 ovary: 18.1 gallbladder: 14.8 -SPEF2 CT122, FLJ23577, KPL2 ENSG00000152582 Sperm flagellar 2 5 35617844-35814611 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039606, HPA040343 Supported Mixed fallopian tube: 25.1 -SPARCL1 MAST9 ENSG00000152583 SPARC-like 1 (hevin) 4 87473335-87531061 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026225, HPA067641 Approved Approved Endoplasmic reticulum Mixed cerebral cortex: 2041.4 -DSPP DFNA39, DGI1, DMP3 ENSG00000152591 Dentin sialophosphoprotein 4 87608529-87616910 Disease related genes, Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level HPA036230 Uncertain Not detected epididymis: 0.0 -DMP1 ENSG00000152592 Dentin matrix acidic phosphoprotein 1 4 87650307-87664361 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA037465 Approved Not detected testis: 0.8 -MEPE ENSG00000152595 Matrix extracellular phosphoglycoprotein 4 87821411-87846817 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038003, HPA038004 Uncertain Tissue enriched 41 cerebral cortex: 4.0 epididymis: 0.0 -MBNL1 EXP, EXP35, EXP40, EXP42, KIAA0428, MBNL ENSG00000152601 Muscleblind-like splicing regulator 1 3 152243828-152465780 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016398, HPA035098, HPA062046 Supported Supported Nucleoplasm
Cytosol Expressed in all smooth muscle: 179.7 -CAPSL MGC26610 ENSG00000152611 Calcyphosine-like 5 35904295-35938779 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046811, HPA058495 Supported Approved Nucleus
Microtubules Tissue enriched 10 fallopian tube: 173.5 testis: 17.3 -NADK2 C5orf33, FLJ30596, MNADK, NADKD1 ENSG00000152620 NAD kinase 2, mitochondrial 5 36192592-36242279 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038366, HPA038367, HPA061492 Supported Expressed in all liver: 173.1 -GPD1L KIAA0089 ENSG00000152642 Glycerol-3-phosphate dehydrogenase 1-like 3 32105689-32168713 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all prostate: 97.8 -GJA1 CX43, GJAL, ODD, ODDD, ODOD, SDTY3 ENSG00000152661 Gap junction protein, alpha 1, 43kDa 6 121435692-121449727 Cancer-related genes, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010753, HPA035097 Supported Approved Tissue enhanced 0 parathyroid gland: 639.4 skin: 470.1 -CCNO CCNU, FLJ22422, UDG2, UNG2 ENSG00000152669 Cyclin O 5 55231152-55233680 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA050090 Uncertain Tissue enhanced 0 testis: 6.9 seminal vesicle: 1.6 -DDX4 VASA ENSG00000152670 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 5 55738017-55817157 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026170, HPA037763, HPA037764 Supported Tissue enriched 506 testis: 269.2 tonsil: 0.5 -CLEC4F CLECSF13, FLJ39110, KCLR ENSG00000152672 C-type lectin domain family 4, member F 2 70808643-70820600 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed small intestine: 5.0 -SLC30A6 FLJ31101, ZNT6 ENSG00000152683 Solute carrier family 30 (zinc transporter), member 6 2 32165841-32224379 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055032, HPA057328 Uncertain Validated Golgi apparatus Expressed in all thyroid gland: 19.7 -PELO ENSG00000152684 Pelota homolog (Drosophila) 5 52787940-52804046 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031458 Approved Approved Nucleoli fibrillar center Expressed in all adrenal gland: 20.1 -RASGRP3 GRP3, KIAA0846 ENSG00000152689 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2 33436324-33564750 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058937 Approved Nucleoplasm
Golgi apparatus Mixed lymph node: 34.3 -SAR1B SARA2 ENSG00000152700 Secretion associated, Ras related GTPase 1B 5 134601144-134649271 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006923, HPA048368 Supported Approved Endoplasmic reticulum Expressed in all testis: 117.9 -CATSPER3 CACRC ENSG00000152705 Cation channel, sperm associated 3 5 134967906-135011707 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 26 testis: 38.3 fallopian tube: 1.4 -GPR180 ITR ENSG00000152749 G protein-coupled receptor 180 13 94601903-94634645 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047250 Approved Approved Vesicles Mixed adipose tissue: 6.3 -TCTEX1D1 FLJ40873 ENSG00000152760 Tctex1 domain containing 1 1 66752459-66778787 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA028420 Uncertain Tissue enhanced 0 fallopian tube: 16.4;placenta: 9.5 liver: 4.0 -WDR78 DIC4, FLJ23129 ENSG00000152763 WD repeat domain 78 1 66812885-66924887 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045793 Uncertain Group enriched 5 fallopian tube: 43.2;testis: 62.6 parathyroid gland: 9.7 -ANKRD22 MGC22805 ENSG00000152766 Ankyrin repeat domain 22 10 88822132-88851818 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA012922 Approved Approved Nucleus Tissue enhanced 0 skin: 38.6;stomach: 48.9 esophagus: 27.1 -FARP1 CDEP, MGC87400, PLEKHC2, PPP1R75 ENSG00000152767 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 13 98142562-98455176 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000760 Supported Cytosol Mixed thyroid gland: 79.2 -IFIT5 RI58 ENSG00000152778 Interferon-induced protein with tetratricopeptide repeats 5 10 89414586-89421001 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037957, HPA062180 Uncertain Supported Vesicles
Plasma membrane Mixed parathyroid gland: 35.6 -SLC16A12 MCT12 ENSG00000152779 Solute carrier family 16, member 12 10 89430299-89556641 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 62.5;kidney: 93.6 seminal vesicle: 20.0 -PANK1 MGC24596, PANK, PANK1a, PANK1b ENSG00000152782 Pantothenate kinase 1 10 89579497-89645572 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 kidney: 46.3;liver: 55.0 duodenum: 21.2 -PRDM8 ENSG00000152784 PR domain containing 8 4 80183879-80204329 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA057253 Approved Nuclear bodies Tissue enhanced 0 prostate: 41.3;seminal vesicle: 37.8 cerebral cortex: 23.3 -BMP3 ENSG00000152785 Bone morphogenetic protein 3 4 81030965-81057531 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 urinary bladder: 21.3 lung: 8.7 -HNRNPDL HNRPDL, JKTBP, laAUF1 ENSG00000152795 Heterogeneous nuclear ribonucleoprotein D-like 4 82422564-82430408 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056820, HPA063147 Supported Validated Nucleoplasm Expressed in all endometrium: 420.2 -HHEX HEX, HOX11L-PEN, PRHX ENSG00000152804 Hematopoietically expressed homeobox 10 92689951-92695646 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051894, HPA055460 Approved Approved Nucleoplasm
Mitochondria Expressed in all thyroid gland: 163.9 -UTRN DMDL, DRP, DRP1 ENSG00000152818 Utrophin 6 144285701-144853034 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016348, HPA018894 Supported Approved Nucleoplasm
Plasma membrane Expressed in all parathyroid gland: 171.0 -GRM1 GPRC1A, mGlu1, MGLUR1, PPP1R85 ENSG00000152822 Glutamate receptor, metabotropic 1 6 146027646-146437598 Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA015701 Approved Approved Vesicles Tissue enhanced 0 cerebral cortex: 7.1 heart muscle: 1.4 -PTPRK R-PTP-kappa ENSG00000152894 Protein tyrosine phosphatase, receptor type, K 6 127968779-128520674 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054056, HPA054822 Uncertain Supported Vesicles
Plasma membrane
Cell Junctions Mixed gallbladder: 27.9 -GGPS1 GGPPS1 ENSG00000152904 Geranylgeranyl diphosphate synthase 1 1 235327350-235344532 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029472 Supported Expressed in all testis: 89.7 -CNTNAP4 CASPR4, KIAA1763 ENSG00000152910 Contactin associated protein-like 4 16 76277278-76559238 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031859, HPA057342 Supported Tissue enriched 21 cerebral cortex: 36.0 testis: 1.6 -ZNF117 H-plk, HPF9 ENSG00000152926 Zinc finger protein 117 7 64971776-65006684 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA031148 Approved Nucleoli fibrillar center
Cytosol Mixed adrenal gland: 25.2 -RAB3C ENSG00000152932 RAB3C, member RAS oncogene family 5 58582221-58859394 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003160, HPA048156 Supported Approved Cytosol Group enriched 16 adrenal gland: 12.1;cerebral cortex: 55.5 small intestine: 2.0 -LMNTD1 FLJ36004, IFLTD1, Pas1c1 ENSG00000152936 Lamin tail domain containing 1 12 25409307-25648579 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA038640, HPA045911 Uncertain Approved Nucleoplasm
Centrosome Group enriched 7 fallopian tube: 26.9;testis: 26.5 rectum: 3.9 -MARVELD2 DFNB49, FLJ30532, MRVLDC2, TRIC ENSG00000152939 MARVEL domain containing 2 5 69415112-69444330 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018119, HPA061726 Uncertain Supported Cell Junctions Tissue enhanced 0 thyroid gland: 19.7 small intestine: 8.9 -RAD17 CCYC, RAD17Sp, Rad24 ENSG00000152942 RAD17 checkpoint clamp loader component 5 69369293-69414801 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004551, HPA005448 Approved Validated Nucleoplasm Expressed in all testis: 39.2 -MED21 SRB7, SURB7 ENSG00000152944 Mediator complex subunit 21 12 27022546-27066343 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017177 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all testis: 69.0 -PLOD2 LH2 ENSG00000152952 Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 3 146069440-146163653 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025898, HPA069126 Approved Uncertain Nucleoli
Cytosol Mixed thyroid gland: 150.3 -STK32B HSA250839, STK32, STKG6, YANK2 ENSG00000152953 Serine/threonine kinase 32B 4 5051442-5500998 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA015820, HPA058536 Uncertain Approved Microtubules Tissue enhanced 0 kidney: 15.7 testis: 8.6 -NRSN1 p24, VMP ENSG00000152954 Neurensin 1 6 24126122-24154900 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA061006 Approved Approved Nucleus
Vesicles Tissue enriched 14 cerebral cortex: 96.7 adrenal gland: 6.7 -JAKMIP1 FLJ31564, Gababrbp, JAMIP1, MARLIN1 ENSG00000152969 Janus kinase and microtubule interacting protein 1 4 6026199-6200591 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044570 Uncertain Tissue enriched 5 cerebral cortex: 38.5 prostate: 7.4 -ZIC1 ZIC, ZNF201 ENSG00000152977 Zic family member 1 3 147393422-147510293 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA004098 Supported Supported Nucleoplasm Tissue enriched 9 cerebral cortex: 23.8 skin: 2.5 -ADGRA3 FLJ38547, GPR125, PGR21 ENSG00000152990 Adhesion G protein-coupled receptor A3 4 22345071-22516054 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008904 Uncertain Expressed in all thyroid gland: 42.3 -CPB1 ENSG00000153002 Carboxypeptidase B1 (tissue) 3 148791102-148860187 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026158, HPA038069, HPA046340 Supported Tissue enriched 311 pancreas: 47265.6 ovary: 151.9 -SREK1IP1 FLJ36754, P18SRP, SFRS12IP1 ENSG00000153006 SREK1-interacting protein 1 5 64718144-64768685 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045677, HPA062853 Approved Approved Nucleus
Nucleoli Expressed in all placenta: 15.6 -LGI2 FLJ10675, KIAA1916 ENSG00000153012 Leucine-rich repeat LGI family, member 2 4 24998847-25030879 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA017140 Approved Approved Centrosome Tissue enriched 19 parathyroid gland: 364.8 smooth muscle: 19.4 -CWC27 NY-CO-10, SDCCAG-10, SDCCAG10 ENSG00000153015 CWC27 spliceosome-associated protein homolog 5 64768930-65018763 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020344, HPA024149, HPA065809 Approved Validated Nucleoplasm Expressed in all testis: 31.0 -MR1 HLALS ENSG00000153029 Major histocompatibility complex, class I-related 1 181033425-181061938 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA048304 Supported Plasma membrane Mixed thyroid gland: 28.1 -SRP19 ENSG00000153037 Signal recognition particle 19kDa 5 112861222-112869788 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029272 Approved Expressed in all thyroid gland: 64.7 -CENPH ENSG00000153044 Centromere protein H 5 69189548-69210357 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036494 Approved Supported Nucleus
Nucleoli Tissue enhanced 0 testis: 53.6 lymph node: 20.8 -CDYL CDYL1, DKFZP586C1622 ENSG00000153046 Chromodomain protein, Y-like 6 4706159-4955551 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012249, HPA035577, HPA035578 Supported Validated Nucleoplasm
Nuclear speckles Expressed in all placenta: 27.5 -CARHSP1 CRHSP-24, CSDC1 ENSG00000153048 Calcium regulated heat stable protein 1, 24kDa 16 8852942-8869012 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051911 Approved Expressed in all testis: 261.5 -TEKT5 CT149, FLJ32871 ENSG00000153060 Tektin 5 16 10627501-10694945 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043578 Supported Actin filaments Tissue enriched 46 testis: 45.4 stomach: 0.9 -BANK1 BANK, FLJ20706 ENSG00000153064 B-cell scaffold protein with ankyrin repeats 1 4 101411286-102074812 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037002 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Group enriched 5 appendix: 47.6;lymph node: 97.9;spleen: 78.5;thyroid gland: 21.5;tonsil: 90.9 urinary bladder: 13.3 -TXNDC11 EFP1 ENSG00000153066 Thioredoxin domain containing 11 16 11679080-11742878 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041174, HPA041390 Supported Supported Plasma membrane
Cytosol Expressed in all parathyroid gland: 83.0 -DAB2 DOC-2 ENSG00000153071 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 5 39371675-39462300 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009314, HPA028888 Supported Supported Nucleoli
Vesicles
Plasma membrane Expressed in all placenta: 319.5 -ACMSD ENSG00000153086 Aminocarboxymuconate semialdehyde decarboxylase 2 134838547-134902034 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010533, HPA011179 Supported Uncertain Cytosol Group enriched 10 kidney: 136.5;liver: 80.0 gallbladder: 10.9 -ACOXL FLJ11042 ENSG00000153093 Acyl-CoA oxidase-like 2 110732573-111118222 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA035392, HPA035393 Uncertain Supported Nucleoli
Cytosol Group enriched 5 epididymis: 9.2;lung: 14.6;parathyroid gland: 7.4;prostate: 5.5;testis: 5.3;urinary bladder: 8.0 thyroid gland: 1.6 -BCL2L11 BIM, BimEL, BimL, BimS, BOD ENSG00000153094 BCL2-like 11 (apoptosis facilitator) 2 111119378-111168447 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB026332 Approved Expressed in all thyroid gland: 33.4 -ANAPC1 APC1, MCPR, TSG24 ENSG00000153107 Anaphase promoting complex subunit 1 2 111766271-111884690 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036329, HPA036330, HPA042998 Approved Approved Vesicles Expressed in all testis: 20.3 -CAST ENSG00000153113 Calpastatin 5 96525267-96779595 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009491, HPA036881, HPA036882 Approved Validated Endoplasmic reticulum
Cytosol Expressed in all esophagus: 403.4 -SCOC HRIHFB2072, SCOCO ENSG00000153130 Short coiled-coil protein 4 140257286-140385726 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061198, HPA070321 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all cerebral cortex: 188.5 -CLGN ENSG00000153132 Calmegin 4 140388455-140427968 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020709, HPA048761, HPA058627 Supported Validated Endoplasmic reticulum Tissue enhanced 0 testis: 185.4 heart muscle: 39.1 -CETN3 CEN3 ENSG00000153140 Centrin, EF-hand protein, 3 5 90392261-90409786 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035608, HPA063704 Approved Supported Centrosome Tissue enriched 6 testis: 225.3 ovary: 36.7 -SMARCA5 hISWI, hSNF2H, ISWI ENSG00000153147 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 4 143513463-143557486 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005227, HPA008751 Supported Supported Nucleus
Nucleoli fibrillar center Expressed in all testis: 59.0 -SYCP2L C6orf177, dJ62D2.1, NO145 ENSG00000153157 Synaptonemal complex protein 2-like 6 10886831-10979320 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA034679 Uncertain Supported Nucleoplasm Tissue enriched 20 parathyroid gland: 120.4 testis: 5.9 -BMP6 VGR, VGR1 ENSG00000153162 Bone morphogenetic protein 6 6 7726797-7881422 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB002773, HPA062683 Approved Approved Mitochondria Tissue enhanced 0 placenta: 33.1 lung: 10.5 -RGPD3 RGP3 ENSG00000153165 RANBP2-like and GRIP domain containing 3 2 106391290-106468376 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA049497, HPA051675, HPA067564 Uncertain Approved Nuclear membrane
Vesicles Tissue enriched 13 testis: 11.7 kidney: 0.9 -RASSF3 ENSG00000153179 Ras association (RalGDS/AF-6) domain family member 3 12 64610513-64697567 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022664, CAB034035, HPA038469 Supported Supported Plasma membrane
Cytosol Expressed in all smooth muscle: 85.0 -HNRNPU hnRNPU, HNRPU, SAF-A ENSG00000153187 Heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 1 244851166-244864542 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011532, HPA041057, HPA058707 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 216.8 -RANBP2 ADANE, ANE1, NUP358 ENSG00000153201 RAN binding protein 2 2 108719481-108785811 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564 Supported Validated Nuclear membrane
Vesicles Expressed in all parathyroid gland: 73.6 -AHCTF1 ELYS ENSG00000153207 AT hook containing transcription factor 1 1 246839098-246931978 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031658 Uncertain Supported Nuclear membrane Expressed in all testis: 61.2 -MERTK c-Eyk, mer, RP38, Tyro12 ENSG00000153208 MER proto-oncogene, tyrosine kinase 2 111898479-112029561 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036196, HPA075622 Approved Approved Endoplasmic reticulum
Plasma membrane
Cytosol Mixed adrenal gland: 77.4 -TMEM87B FLJ14681 ENSG00000153214 Transmembrane protein 87B 2 112055223-112119318 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035183 Approved Approved Golgi apparatus
Vesicles Mixed prostate: 43.2 -OR14K1 OR5AY1 ENSG00000153230 Olfactory receptor, family 14, subfamily K, member 1 1 247738615-247739559 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA016643 Uncertain Not detected testis: 0.3 -PTPRR EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ ENSG00000153233 Protein tyrosine phosphatase, receptor type, R 12 70638073-70920843 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011461, HPA011851, HPA071067 Uncertain Supported Plasma membrane
Cell Junctions
Cytosol Tissue enhanced 0 cerebral cortex: 20.9 endometrium: 8.9 -NR4A2 HZF-3, NOT, NURR1, RNR1, TINUR ENSG00000153234 Nuclear receptor subfamily 4, group A, member 2 2 156324432-156342348 Cancer-related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA000543, CAB010481 Uncertain Supported Nuclear speckles Tissue enhanced 0 adrenal gland: 175.5 ovary: 95.2 -CCDC148 MGC125588 ENSG00000153237 Coiled-coil domain containing 148 2 158171081-158456753 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042626 Uncertain Approved Nucleus
Nucleoli Tissue enhanced 0 parathyroid gland: 4.1;testis: 5.7 fallopian tube: 2.4 -PLA2R1 CLEC13C, PLA2-R, PLA2G1R, PLA2IR ENSG00000153246 Phospholipase A2 receptor 1, 180kDa 2 159932006-160062610 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB068217, CAB068218 Approved Approved Cytosol Tissue enhanced 0 thyroid gland: 71.7 parathyroid gland: 35.1 -RBMS1 C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1 ENSG00000153250 RNA binding motif, single stranded interacting protein 1 2 160272151-160493794 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047943, HPA061791 Supported Cytosol Expressed in all placenta: 119.0 -SCN3A Nav1.3 ENSG00000153253 Sodium channel, voltage gated, type III alpha subunit 2 165087522-165204067 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035396 Approved Tissue enriched 6 cerebral cortex: 18.0 adrenal gland: 3.0 -FEZF2 FEZL, FKSG36, FLJ10142, TOF, Zfp312, ZNF312 ENSG00000153266 FEZ family zinc finger 2 3 62369681-62374324 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 29 cerebral cortex: 11.8 colon: 0.4 -CD96 TACTILE ENSG00000153283 CD96 molecule 3 111292719-111665750 CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066754 Supported Tissue enhanced 0 lymph node: 28.4 urinary bladder: 17.4 -SLC25A27 FLJ33552, UCP4 ENSG00000153291 Solute carrier family 25, member 27 6 46652915-46678193 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA069732 Supported Mitochondria Mixed epididymis: 83.8 -ADGRF1 GPR110, hGPCR36, PGR19 ENSG00000153292 Adhesion G protein-coupled receptor F1 6 46997703-47042363 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038438 Approved Tissue enhanced 0 esophagus: 14.7;kidney: 17.6;urinary bladder: 19.6 gallbladder: 9.5 -ADGRF4 FLJ38076, GPR115, PGR18 ENSG00000153294 Adhesion G protein-coupled receptor F4 6 47685864-47722021 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA007131, HPA007158 Supported Uncertain Mitochondria Group enriched 7 esophagus: 12.1;skin: 45.9 tonsil: 3.9 -FRMD1 bA164L23.1, DKFZp434O0117, FLJ00181, FLJ22615, FLJ40260 ENSG00000153303 FERM domain containing 1 6 168055745-168081557 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030346, HPA030347 Uncertain Approved Actin filaments Tissue enhanced 0 colon: 5.9;stomach: 6.2;testis: 5.9 rectum: 4.6 -FAM49B BM-009 ENSG00000153310 Family with sequence similarity 49, member B 8 129839593-130017129 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009076 Approved Approved Nucleus
Cytosol Expressed in all lymph node: 139.1 -ASAP1 CENTB4, DDEF1, KIAA1249, PAP, ZG14P ENSG00000153317 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 8 130052104-130443660 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011136, CAB037292, HPA048565 Approved Approved Plasma membrane
Centrosome
Cytosol Expressed in all testis: 56.0 -TRAPPC8 GSG1, HsT2706, KIAA1012, TRS85 ENSG00000153339 Trafficking protein particle complex 8 18 31829173-31953136 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041107 Approved Approved Microtubules
Cytosol Expressed in all testis: 53.9 -FAM81B FLJ25333 ENSG00000153347 Family with sequence similarity 81, member B 5 95391344-95450454 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072554 Uncertain Group enriched 13 fallopian tube: 77.9;testis: 120.1 parathyroid gland: 7.3 -INO80C C18orf37, FLJ38183, hIes6, IES6 ENSG00000153391 INO80 complex subunit C 18 35452230-35497991 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049060 Approved Supported Nucleoli fibrillar center Expressed in all testis: 165.6 -LPCAT1 AGPAT10, AGPAT9, AYTL2, FLJ12443 ENSG00000153395 Lysophosphatidylcholine acyltransferase 1 5 1456480-1523977 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012501, HPA022268 Supported Supported Endoplasmic reticulum
Lipid droplets Tissue enhanced 0 lung: 19.2;spleen: 15.1 cerebral cortex: 4.4 -PLEKHG4B KIAA1909 ENSG00000153404 Pleckstrin homology domain containing, family G (with RhoGef domain) member 4B 5 140258-189970 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036274, HPA058157 Uncertain Approved Nucleoplasm Tissue enhanced 0 thyroid gland: 5.2 testis: 3.2 -NMRAL1 FLJ25918, HSCARG, SDR48A1 ENSG00000153406 NmrA-like family domain containing 1 16 4461680-4495763 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041353, HPA062287 Uncertain Validated Nucleus Mixed fallopian tube: 21.2 -UBALD1 FAM100A ENSG00000153443 UBA-like domain containing 1 16 4608883-4615027 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA066771 Approved Approved Nucleus
Cell Junctions
Cytosol Expressed in all cerebral cortex: 23.9 -C16orf89 MGC45438 ENSG00000153446 Chromosome 16 open reading frame 89 16 5044122-5066110 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA013613 Approved Tissue enhanced 0 lung: 145.5;thyroid gland: 351.2 epididymis: 92.6 -TMEM251 C14orf109, DKFZP564F1123 ENSG00000153485 Transmembrane protein 251 14 93184951-93187089 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048559 Uncertain Approved Golgi apparatus
Cell Junctions Expressed in all prostate: 27.9 -ING1 p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a ENSG00000153487 Inhibitor of growth family, member 1 13 110712736-110723339 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016136, CAB017773, HPA052591 Approved Approved Nucleoplasm
Cytosol Expressed in all ovary: 20.9 -TEX29 bA474D23.1, C13orf16, MGC35169 ENSG00000153495 Testis expressed 29 13 111316184-111344249 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 15 testis: 46.7 cerebral cortex: 3.0 -SPACA7 C13orf28 ENSG00000153498 Sperm acrosome associated 7 13 112376319-112434689 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 43 testis: 50.1 liver: 1.1 -ADPRHL1 ARH2 ENSG00000153531 ADP-ribosylhydrolase like 1 13 113399610-113453524 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA066478 Supported Approved Nucleoplasm Group enriched 14 heart muscle: 252.1;skeletal muscle: 114.3 fallopian tube: 13.2 -CMTM7 CKLFSF7, FLJ30992 ENSG00000153551 CKLF-like MARVEL transmembrane domain containing 7 3 32391671-32483067 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA077409 Approved Plasma membrane Mixed fallopian tube: 60.9 -FBXL2 FBL2, FBL3 ENSG00000153558 F-box and leucine-rich repeat protein 2 3 33277025-33403662 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061783 Approved Nucleus
Nucleoli
Plasma membrane Mixed cerebral cortex: 5.8 -UBP1 LBP-1a ENSG00000153560 Upstream binding protein 1 (LBP-1a) 3 33388336-33441371 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003967 Supported Nucleoplasm Expressed in all seminal vesicle: 53.9 -RMND5A FLJ13910, GID2, GID2A, p44CTLH, RMD5 ENSG00000153561 Required for meiotic nuclear division 5 homolog A 2 86720173-86778041 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046795, HPA060843 Uncertain Approved Nucleoplasm Expressed in all parathyroid gland: 38.5 -CD8A CD8 ENSG00000153563 CD8a molecule 2 86784610-86808396 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000012, HPA037756, CAB075722 Supported Tissue enhanced 0 spleen: 164.7 lymph node: 47.7 -RPIA ENSG00000153574 Ribose 5-phosphate isomerase A 2 88691644-88750935 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042620, HPA057954 Approved Approved Nucleoplasm
Vesicles
Plasma membrane Expressed in all bone marrow: 54.3 -GOLGA8F DKFZp434P162 ENSG00000153684 Golgin A8 family, member F 15 28378621-28392018 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 51 testis: 5.0 epididymis: 0.0 -PTPRD HPTP, PTPD ENSG00000153707 Protein tyrosine phosphatase, receptor type, D 9 8314246-10612723 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054829 Uncertain Approved Vesicles Tissue enhanced 0 cerebral cortex: 32.5;parathyroid gland: 46.2 ovary: 11.6 -LURAP1L bA3L8.2, C9orf150, FLJ38505, MGC46502 ENSG00000153714 Leucine rich adaptor protein 1-like 9 12775021-12822131 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024407 Uncertain Approved Nucleus
Nucleoli Mixed placenta: 42.6 -CNKSR3 FLJ31349, MAGI1 ENSG00000153721 CNKSR family member 3 6 154159828-154510659 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028708, CAB037133, HPA049651 Approved Approved Mitochondria
Cytosol Mixed esophagus: 15.8 -GTF2E1 FE, TFIIE-A ENSG00000153767 General transcription factor IIE, polypeptide 1, alpha 56kDa 3 120742637-120783069 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009884, HPA056359, HPA066881 Supported Validated Nucleus
Cytosol Mixed testis: 18.4 -CFDP1 BCNT, CENP-29, CP27, p97, SWC5, Yeti ENSG00000153774 Craniofacial development protein 1 16 75293698-75433485 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041316, HPA048242 Approved Supported Nucleoplasm Expressed in all testis: 112.0 -TGIF2LX ENSG00000153779 TGFB-induced factor homeobox 2-like, X-linked X 89921882-89922883 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034543 Supported Approved Nucleoplasm Tissue enriched 134 testis: 13.3 epididymis: 0.0 -ZDHHC7 FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370 ENSG00000153786 Zinc finger, DHHC-type containing 7 16 84974181-85011535 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019215, HPA059054, HPA059642 Uncertain Validated Golgi apparatus Expressed in all parathyroid gland: 63.6 -FAM92B FLJ44299 ENSG00000153789 Family with sequence similarity 92, member B 16 85098358-85112508 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041022 Supported Tissue enriched 9 fallopian tube: 134.5 lung: 14.2 -C7orf31 ENSG00000153790 Chromosome 7 open reading frame 31 7 25134697-25180356 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020346 Approved Nucleoplasm
Mitochondria Tissue enriched 14 testis: 130.7 parathyroid gland: 9.4 -TMPRSS11D ENSG00000153802 Transmembrane protease, serine 11D 4 67820876-67884032 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052834 Uncertain Group enriched 39 esophagus: 70.8;tonsil: 31.7 cervix: 1.3 -JAZF1 DKFZp761K2222, TIP27, ZNF802 ENSG00000153814 JAZF zinc finger 1 7 27830573-28180743 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019271, HPA066967 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all adrenal gland: 113.6 -CMIP ENSG00000153815 C-Maf inducing protein 16 81445170-81711762 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054424, HPA066710 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 87.6 -SPHKAP SKIP ENSG00000153820 SPHK1 interactor, AKAP domain containing 2 227979950-228181645 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042499, HPA048168 Supported Group enriched 7 cerebral cortex: 19.5;heart muscle: 20.3 ovary: 2.7 -KCNJ16 BIR9, Kir5.1 ENSG00000153822 Potassium channel, inwardly rectifying subfamily J, member 16 17 70053429-70135608 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059563 Approved Uncertain Vesicles Group enriched 7 kidney: 207.9;parathyroid gland: 268.8;thyroid gland: 233.9 seminal vesicle: 31.9 -PID1 FLJ20701, NYGGF4 ENSG00000153823 Phosphotyrosine interaction domain containing 1 2 228850526-229271285 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036103 Approved Approved Endoplasmic reticulum Expressed in all cerebral cortex: 67.4 -TRIP12 KIAA0045 ENSG00000153827 Thyroid hormone receptor interactor 12 2 229763838-229923239 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036835, HPA045893 Supported Approved Nuclear speckles Expressed in all testis: 271.5 -FBXO36 Fbx36, FLJ37592 ENSG00000153832 F-box protein 36 2 229922302-230013109 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA053865 Approved Nucleus
Nucleoli Tissue enhanced 0 fallopian tube: 17.4 thyroid gland: 12.4 -CEBPG GPE1BP, IG/EBP-1 ENSG00000153879 CCAAT/enhancer binding protein (C/EBP), gamma 19 33373330-33382686 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012024 Supported Supported Nucleoplasm Expressed in all thyroid gland: 41.2 -KCTD15 MGC25497 ENSG00000153885 Potassium channel tetramerization domain containing 15 19 33795933-33815763 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050822 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all skin: 86.4 -ZNF599 FLJ30663 ENSG00000153896 Zinc finger protein 599 19 34758076-34773229 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA014701 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Mixed epididymis: 14.4 -MCOLN2 FLJ36691, TRP-ML2, TRPML2 ENSG00000153898 Mucolipin 2 1 84925583-84997113 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at transcript level HPA019114, HPA048999 Uncertain Supported Intermediate filaments Mixed rectum: 17.6 -LGI4 ENSG00000153902 Leucine-rich repeat LGI family, member 4 19 35124513-35142451 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042116, HPA043556 Approved Approved Golgi apparatus Mixed cerebral cortex: 26.2 -DDAH1 DDAH ENSG00000153904 Dimethylarginine dimethylaminohydrolase 1 1 85318481-85578363 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006308 Supported Approved Nucleoli
Plasma membrane
Cytosol Mixed kidney: 119.5 -SREK1 DKFZp564B176, SFRS12, SRrp508, SRrp86 ENSG00000153914 Splicing regulatory glutamine/lysine-rich protein 1 5 66139971-66183615 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037673, HPA037674, HPA059332 Supported Validated Nucleoplasm
Nuclear speckles Mixed parathyroid gland: 14.8 -CHD1 ENSG00000153922 Chromodomain helicase DNA binding protein 1 5 98853985-98928957 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022236 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all bone marrow: 44.4 -ANKFN1 FLJ38335 ENSG00000153930 Ankyrin-repeat and fibronectin type III domain containing 1 17 56110958-56511659 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021566, HPA022538 Uncertain Tissue enhanced 0 cervix, uterine: 14.1;fallopian tube: 8.3 cerebral cortex: 3.1 -DGKE DAGK6, DGK ENSG00000153933 Diacylglycerol kinase, epsilon 64kDa 17 56834099-56869567 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017167 Approved Approved Nucleus
Cytosol Mixed testis: 12.1 -HS2ST1 KIAA0448 ENSG00000153936 Heparan sulfate 2-O-sulfotransferase 1 1 86914648-87109998 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043069, HPA043603, HPA075001 Supported Approved Mitochondria Expressed in all adrenal gland: 34.2 -MSI2 ENSG00000153944 Musashi RNA-binding protein 2 17 57255851-57684685 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022300 Approved Supported Cytosol Expressed in all parathyroid gland: 117.6 -CACNA2D1 CACNA2, CACNL2A, LINC01112, lncRNA-N3, MHS3 ENSG00000153956 Calcium channel, voltage-dependent, alpha 2/delta subunit 1 7 81946444-82443798 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008213, HPA008621 Supported Mixed cerebral cortex: 35.5 -ZUFSP C6orf113, dJ412I7.3 ENSG00000153975 Zinc finger with UFM1-specific peptidase domain 6 116635618-116668794 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044426 Uncertain Approved Nucleoplasm
Cytosol Mixed testis: 10.7 -HS3ST3A1 30ST3A1, 3OST3A1 ENSG00000153976 Heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 17 13495689-13601927 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA062518, HPA071530 Uncertain Approved Microtubules Tissue enhanced 0 spleen: 9.3 seminal vesicle: 6.7 -GDPD1 FLJ37451, GDE4 ENSG00000153982 Glycerophosphodiester phosphodiesterase domain containing 1 17 59220467-59275967 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 28.0 testis: 19.9 -NUS1 C6orf68, MGC7199, NgBR, TANGO14 ENSG00000153989 NUS1 dehydrodolichyl diphosphate synthase subunit 6 117675502-117710640 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027504 Supported Approved Vesicles
Plasma membrane Expressed in all cervix: 91.7 -SEMA3D coll-2, Sema-Z2 ENSG00000153993 Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 7 84995553-85186855 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA037522 Uncertain Approved Golgi apparatus
Plasma membrane Group enriched 5 spleen: 67.1;thyroid gland: 76.0 prostate: 13.5 -PPP2R5E ENSG00000154001 Protein phosphatase 2, regulatory subunit B', epsilon isoform 14 63371357-63543374 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006034 Approved Supported Cytosol Expressed in all thyroid gland: 33.7 -ASB17 ENSG00000154007 Ankyrin repeat and SOCS box containing 17 1 75918873-75932431 Plasma proteins, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 381 testis: 84.0 kidney: 0.2 -GRAP ENSG00000154016 GRB2-related adaptor protein 17 19020673-19047637 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046595, HPA066654 Uncertain Approved Centrosome Tissue enhanced 0 lymph node: 31.4;spleen: 25.7 tonsil: 20.4 -SLC5A10 SGLT5 ENSG00000154025 Solute carrier family 5 (sodium/sugar cotransporter), member 10 17 18950345-19022595 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052014 Uncertain Tissue enriched 25 kidney: 43.7 bone marrow: 1.7 -AK5 ENSG00000154027 Adenylate kinase 5 1 77282051-77559969 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019128, HPA057255 Supported Supported Microtubule organizing center
Cytosol Tissue enriched 9 cerebral cortex: 221.4 breast: 23.3 -CABYR CBP86, CT88, FSP-2 ENSG00000154040 Calcium binding tyrosine-(Y)-phosphorylation regulated 18 24138956-24161603 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040703, HPA047801 Supported Supported Nucleus
Cytosol Tissue enriched 39 testis: 444.2 cerebral cortex: 11.2 -IMPACT RWDD5 ENSG00000154059 Impact RWD domain protein 18 24426616-24453535 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041045, HPA041968 Approved Approved Nucleoplasm Expressed in all testis: 64.9 -ANKRD29 FLJ25053 ENSG00000154065 Ankyrin repeat domain 29 18 23598926-23662885 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041272, HPA049419 Uncertain Approved Nucleoplasm
Nuclear bodies Mixed lung: 47.5 -SDHAF4 C6orf57, Sdh8 ENSG00000154079 Succinate dehydrogenase complex assembly factor 4 6 70566917-70589569 Predicted secreted proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA031824 Supported Approved Nucleus
Mitochondria Expressed in all fallopian tube: 17.2 -CHST9 GALNAC-4-ST2, GALNAC4ST-2 ENSG00000154080 Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 18 26906481-27185317 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA011393 Uncertain Tissue enhanced 0 fallopian tube: 16.5;testis: 12.7 spleen: 8.0 -THY1 CD90 ENSG00000154096 Thy-1 cell surface antigen 11 119417378-119424985 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003733, CAB068243, CAB068244 Supported Approved Nucleus
Plasma membrane Tissue enhanced 0 cerebral cortex: 422.9;smooth muscle: 428.6 gallbladder: 161.7 -DNAAF1 CILD13, FLJ25330, LRRC50, ODA7 ENSG00000154099 Dynein, axonemal, assembly factor 1 16 84145287-84178767 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041166 Uncertain Approved Nuclear speckles
Plasma membrane
Cytosol Group enriched 20 fallopian tube: 34.1;testis: 80.2 lung: 2.8 -C16orf74 MGC17624 ENSG00000154102 Chromosome 16 open reading frame 74 16 85690084-85751129 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049367 Uncertain Approved Plasma membrane
Centrosome Mixed urinary bladder: 13.8 -TBCEL LRRC35, MGC10233 ENSG00000154114 Tubulin folding cofactor E-like 11 121024072-121090775 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038593, HPA038594 Approved Approved Cytosol Expressed in all parathyroid gland: 35.1 -JPH3 CAGL237, HDL2, JP-3, JP3, TNRC22 ENSG00000154118 Junctophilin 3 16 87601835-87698156 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA076304 Approved Nucleoplasm
Cytosol Tissue enriched 22 cerebral cortex: 43.4 adrenal gland: 2.0 -ANKH ANK, CCAL2, CMDJ, CPPDD, HANK ENSG00000154122 ANKH inorganic pyrophosphate transport regulator 5 14704804-14871778 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA068104 Approved Cytosol Expressed in all prostate: 49.5 -OTULIN FAM105B, FLJ34884 ENSG00000154124 OTU deubiquitinase with linear linkage specificity 5 14664664-14699711 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051074 Uncertain Approved Plasma membrane
Mitochondria Expressed in all bone marrow: 17.2 -UBASH3B KIAA1959, STS-1, TULA2 ENSG00000154127 Ubiquitin associated and SH3 domain containing B 11 122655675-122814473 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038605, HPA038607 Approved Approved Plasma membrane Tissue enhanced 0 placenta: 19.4;spleen: 21.6 lung: 6.8 -ROBO4 ECSM4, FLJ20798, MRB ENSG00000154133 Roundabout guidance receptor 4 11 124883691-124898500 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065212 Approved Plasma membrane Tissue enhanced 0 spleen: 59.1 adipose tissue: 45.0 -ROBO3 FLJ21044, HGPPS, HGPS, RBIG1 ENSG00000154134 Roundabout guidance receptor 3 11 124865386-124881470 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 smooth muscle: 1.2 spleen: 0.8 -PANX3 Px3 ENSG00000154143 Pannexin 3 11 124611490-124620356 Predicted membrane proteins, Transporters Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.5 -TBRG1 FLJ14621, NIAM, TB-5 ENSG00000154144 Transforming growth factor beta regulator 1 11 124622836-124635398 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055645, HPA068022 Validated Nucleus Expressed in all spleen: 16.3 -NRGN RC3 ENSG00000154146 Neurogranin (protein kinase C substrate, RC3) 11 124739846-124747210 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006908, HPA038171 Supported Tissue enriched 17 cerebral cortex: 964.6 lung: 56.4 -FAM134B FLJ20152, JK1 ENSG00000154153 Family with sequence similarity 134, member B 5 16473038-16617058 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012077 Supported Nuclear bodies
Endoplasmic reticulum Expressed in all heart muscle: 64.0 -CDH12 Br-cadherin, CDHB ENSG00000154162 Cadherin 12, type 2 (N-cadherin 2) 5 21750673-22853622 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029325 Uncertain Approved Vesicles Group enriched 5 adrenal gland: 2.5;cerebral cortex: 3.8;cervix, uterine: 5.3;fallopian tube: 4.0;skin: 1.1;testis: 2.7 breast: 0.6 -GPR15 ENSG00000154165 G protein-coupled receptor 15 3 98531899-98533150 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA013775 Approved Tissue enhanced 0 colon: 25.7;rectum: 47.8 urinary bladder: 19.1 -TOMM70A KIAA0719 ENSG00000154174 Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 3 100363431-100401398 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014589, CAB017156, HPA048020 Supported Validated Mitochondria Expressed in all cerebral cortex: 52.9 -ABI3BP DKFZP586L2024, NESHBP, TARSH ENSG00000154175 ABI family, member 3 (NESH) binding protein 3 100749156-100993515 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044127, HPA048456 Uncertain Uncertain Nucleoli
Nuclear speckles
Centrosome
Cytosol Mixed gallbladder: 159.0 -ANGPT1 Ang1, KIAA0003 ENSG00000154188 Angiopoietin 1 8 107249482-107498055 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017815, HPA018793, HPA018816 Approved Tissue enhanced 0 seminal vesicle: 45.9 lung: 32.5 -PITPNC1 RDGB-BETA, RDGBB, RDGBB1 ENSG00000154217 Phosphatidylinositol transfer protein, cytoplasmic 1 17 67377281-67697261 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026563, HPA031250 Uncertain Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 46.7 -CC2D1B KIAA1836 ENSG00000154222 Coiled-coil and C2 domain containing 1B 1 52345723-52366193 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027500, HPA031426 Uncertain Supported Nucleoplasm
Vesicles Expressed in all lung: 18.8 -CERS3 LASS3, MGC27091 ENSG00000154227 Ceramide synthase 3 15 100400395-100544995 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006092, HPA024356 Uncertain Group enriched 9 esophagus: 48.3;skin: 60.7;testis: 32.1;tonsil: 14.9 breast: 4.2 -PRKCA PKCA ENSG00000154229 Protein kinase C, alpha 17 66302636-66810743 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003844, HPA006563, HPA006564, CAB016290 Approved Validated Plasma membrane
Cytosol Mixed cerebral cortex: 45.1 -LRRK1 FLJ23119, KIAA1790, RIPK6, Roco1 ENSG00000154237 Leucine-rich repeat kinase 1 15 100919215-101078254 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010537 Uncertain Supported Mitochondria
Cytosol Mixed lymph node: 12.7 -CEP112 CCDC46, MGC33887 ENSG00000154240 Centrosomal protein 112kDa 17 65635538-66192084 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024481 Uncertain Approved Nucleoplasm
Golgi apparatus Tissue enriched 6 testis: 85.8 endometrium: 14.3 -GAL3ST2 GP3ST ENSG00000154252 Galactose-3-O-sulfotransferase 2 2 241776825-241804208 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA071809 Supported Group enriched 8 colon: 9.5;rectum: 4.1 appendix: 0.9 -ABCA9 EST640918 ENSG00000154258 ATP-binding cassette, sub-family A (ABC1), member 9 17 68974488-69061064 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054823 Uncertain Mixed ovary: 33.3 -ABCA6 EST155051 ENSG00000154262 ATP-binding cassette, sub-family A (ABC1), member 6 17 69078702-69141888 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064878, HPA067180 Approved Nucleoplasm Tissue enhanced 0 liver: 41.4 ovary: 37.2 -ABCA10 EST698739 ENSG00000154263 ATP-binding cassette, sub-family A (ABC1), member 10 17 69147214-69244846 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014535 Uncertain Mixed ovary: 13.7 -ABCA5 EST90625 ENSG00000154265 ATP-binding cassette, sub-family A (ABC1), member 5 17 69244311-69327244 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA022032 Approved Expressed in all skin: 28.0 -ENPP3 B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3 ENSG00000154269 Ectonucleotide pyrophosphatase/phosphodiesterase 3 6 131628442-131747418 CD markers, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043772 Supported Tissue enhanced 0 cervix, uterine: 45.1;small intestine: 51.0 seminal vesicle: 21.8 -C4orf19 FLJ11017 ENSG00000154274 Chromosome 4 open reading frame 19 4 37453941-37623495 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043458, HPA052894 Approved Supported Cell Junctions Mixed rectum: 27.4 -UCHL1 PARK5, PGP9.5, Uch-L1 ENSG00000154277 Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 4 41256413-41268455 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002580, HPA005993 Supported Validated Nucleoplasm
Cytosol Tissue enriched 7 cerebral cortex: 788.3 adrenal gland: 108.6 -MIA3 FLJ39207, KIAA0268, TANGO, UNQ6077 ENSG00000154305 Melanoma inhibitory activity family, member 3 1 222618086-222668012 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055922, HPA056816 Supported Validated Vesicles Expressed in all testis: 80.7 -DISP1 DISPA, DKFZP434I0428, MGC13130, MGC16796 ENSG00000154309 Dispatched homolog 1 (Drosophila) 1 222872271-223005995 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051411 Uncertain Approved Nuclear bodies Mixed lung: 15.8 -TNIK KIAA0551 ENSG00000154310 TRAF2 and NCK interacting kinase 3 171061339-171460408 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012128, HPA012297 Approved Supported Nucleoplasm
Cytosol Mixed cerebral cortex: 35.6 -FAM167A C8orf13 ENSG00000154319 Family with sequence similarity 167, member A 8 11421463-11474715 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023915, HPA030426 Approved Validated Endoplasmic reticulum Tissue enhanced 0 cerebral cortex: 32.5;thyroid gland: 87.6 lung: 15.8 -NEIL2 FLJ31644, MGC2832, MGC4505, NEH2 ENSG00000154328 Nei-like DNA glycosylase 2 8 11769639-11787346 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064460 Supported Nucleus
Nucleoli Expressed in all testis: 46.1 -PGM5 PGMRP ENSG00000154330 Phosphoglucomutase 5 9 68328308-68531061 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034397, HPA046329 Approved Tissue enhanced 0 prostate: 276.5;seminal vesicle: 324.8 smooth muscle: 215.4 -WNT3A ENSG00000154342 Wingless-type MMTV integration site family, member 3A 1 228007051-228061260 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA066281 Approved Vesicles Tissue enriched 6 placenta: 23.0 lung: 3.9 -OBSCN ARHGEF30, KIAA1556, KIAA1639, UNC89 ENSG00000154358 Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 1 228208130-228378876 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019497, HPA021186 Approved Approved Plasma membrane
Cytosol Tissue enriched 6 skeletal muscle: 249.2 heart muscle: 38.3 -LONRF1 FLJ23749, RNF191 ENSG00000154359 LON peptidase N-terminal domain and ring finger 1 8 12721894-12756073 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023584, HPA024814 Uncertain Approved Plasma membrane
Centrosome
Cytosol Expressed in all skin: 30.8 -TRIM11 BIA1, RNF92 ENSG00000154370 Tripartite motif containing 11 1 228393673-228406840 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028541, HPA043879 Approved Validated Nucleus
Cytosol Mixed bone marrow: 18.9 -ENAH FLJ10773, MENA, NDPP1 ENSG00000154380 Enabled homolog (Drosophila) 1 225486835-225653142 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028448, HPA028696 Supported Validated Plasma membrane
Focal adhesion sites
Cytosol Mixed smooth muscle: 80.4 -PPP1R3A GM, PPP1R3 ENSG00000154415 Protein phosphatase 1, regulatory subunit 3A 7 113876777-114075920 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 22 heart muscle: 26.7;skeletal muscle: 53.1 prostate: 1.8 -CCSAP C1orf96, CSAP, FLJ41471 ENSG00000154429 Centriole, cilia and spindle-associated protein 1 229321005-229343294 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028402, HPA043443 Supported Uncertain Nucleoplasm
Cytokinetic bridge Tissue enhanced 0 cerebral cortex: 54.2 placenta: 18.6 -ASZ1 ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3 ENSG00000154438 Ankyrin repeat, SAM and basic leucine zipper domain containing 1 7 117363222-117428123 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA020558 Supported Approved Nucleoplasm
Cytosol Tissue enriched 195 testis: 19.5 epididymis: 0.0 -SH3RF1 KIAA1494, POSH, RNF142, SH3MD2 ENSG00000154447 SH3 domain containing ring finger 1 4 169094256-169271105 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA074783 Uncertain Vesicles
Intermediate filaments Expressed in all thyroid gland: 32.0 -GBP5 ENSG00000154451 Guanylate binding protein 5 1 89258950-89272804 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028656 Approved Approved Endoplasmic reticulum Tissue enhanced 0 appendix: 103.3 lymph node: 61.2 -BUB3 BUB3L ENSG00000154473 BUB3 mitotic checkpoint protein 10 123154277-123170467 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003601, CAB037075 Supported Validated Nucleoplasm Expressed in all lymph node: 113.5 -GPR26 ENSG00000154478 G protein-coupled receptor 26 10 123666355-123694607 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA062736 Supported Tissue enriched 15 cerebral cortex: 4.3 testis: 0.2 -CCDC173 C2orf77, LOC129881 ENSG00000154479 Coiled-coil domain containing 173 2 169645425-169694433 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042995, HPA048454 Uncertain Tissue enriched 6 testis: 143.0 fallopian tube: 23.2 -MMP21 ENSG00000154485 Matrix metallopeptidase 21 10 125766453-125775821 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 27 epididymis: 58.2 ovary: 2.1 -C10orf90 bA422P15.2, FATS, FLJ32938 ENSG00000154493 Chromosome 10 open reading frame 90 10 126424997-126670446 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038648, HPA057599 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Group enriched 13 breast: 5.6;cerebral cortex: 15.3;salivary gland: 4.4;testis: 12.4 tonsil: 0.7 -FAM69A FLJ23493 ENSG00000154511 Family with sequence similarity 69, member A 1 92832737-92961522 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015718, HPA017281 Approved Approved Nucleus
Cytosol Mixed cerebral cortex: 44.8 -ATP5G3 ENSG00000154518 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 2 175176258-175184607 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all heart muscle: 525.2 -CNTNAP3B ENSG00000154529 Contactin associated protein-like 3B 9 41890314-42129510 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015604, HPA047731 Uncertain Mixed skin: 10.4 -MAGED4 KIAA1859, MAGE-E1, MAGE1, MGC3210 ENSG00000154545 Melanoma antigen family D4 X 52184823-52192268 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA003554 Uncertain Not detected cerebral cortex: 0.7 -SRSF12 SFRS13B, SFRS19, SRrp35 ENSG00000154548 Serine/arginine-rich splicing factor 12 6 89095959-89118081 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049782 Approved Group enriched 6 cerebral cortex: 6.9;testis: 20.9 thyroid gland: 2.2 -PDLIM3 ALP ENSG00000154553 PDZ and LIM domain 3 4 185500660-185535612 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004749 Supported Supported Cytosol Tissue enhanced 0 skeletal muscle: 1097.8 seminal vesicle: 288.8 -SORBS2 ARGBP2, KIAA0777 ENSG00000154556 Sorbin and SH3 domain containing 2 4 185585444-185956652 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036754, HPA036755 Supported Supported Nucleoplasm Tissue enhanced 0 heart muscle: 359.9;thyroid gland: 459.9 parathyroid gland: 276.8 -TCEB1 SIII ENSG00000154582 Transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 8 73939169-73972287 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA078113 Approved Cell Junctions Expressed in all testis: 162.2 -LY96 MD-2 ENSG00000154589 Lymphocyte antigen 96 8 73991352-74029087 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053060 Approved Vesicles Mixed spleen: 62.2 -PSMA8 MGC26605, PSMA7L ENSG00000154611 Proteasome subunit alpha 8 18 26133852-26193355 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 19 testis: 38.7 tonsil: 2.0 -TMSB4Y TB4Y ENSG00000154620 Thymosin beta 4, Y-linked Y 13703567-13706024 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed testis: 5.7 -CXADR CAR ENSG00000154639 Coxsackie virus and adenovirus receptor 21 17512382-17593579 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003342, CAB005103, HPA030411, HPA030412 Supported Validated Plasma membrane
Cell Junctions Mixed skin: 59.6 -BTG3 ANA, tob55 ENSG00000154640 BTG family, member 3 21 17593653-17612947 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018400 Approved Mixed epididymis: 128.6 -C21orf91 C21orf14, C21orf38, CSSG1, EURL, YG81 ENSG00000154642 Chromosome 21 open reading frame 91 21 17788967-17819386 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA018288, HPA049030 Approved Approved Microtubules
Cytokinetic bridge Mixed testis: 44.2 -CHODL C21orf68, FLJ12627, MT75, PRED12 ENSG00000154645 Chondrolectin 21 17901263-18267373 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA017282 Approved Supported Tissue enhanced 0 spleen: 19.7;testis: 57.3 prostate: 8.2 -TMPRSS15 ENTK, MGC133046, PRSS7 ENSG00000154646 Transmembrane protease, serine 15 21 18269116-18485879 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA015611 Supported Tissue enriched 44 duodenum: 1039.0 small intestine: 23.3 -NCAM2 MGC51008, NCAM21 ENSG00000154654 Neural cell adhesion molecule 2 21 20998315-21543329 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030900, HPA030901 Approved Supported Nuclear bodies
Plasma membrane Tissue enhanced 0 cerebral cortex: 69.0 adrenal gland: 15.9 -L3MBTL4 FLJ35936, HsT1031 ENSG00000154655 L(3)mbt-like 4 (Drosophila) 18 5954706-6415237 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA064194, HPA069042 Approved Approved Nucleoplasm
Vesicles Mixed testis: 24.8 -PDE1C Hcam3 ENSG00000154678 Phosphodiesterase 1C, calmodulin-dependent 70kDa 7 31751179-32299329 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021751, HPA052375 Uncertain Approved Nucleus Tissue enhanced 0 heart muscle: 36.6 cerebral cortex: 20.8 -RABGEF1 rabex-5, RABEX5 ENSG00000154710 RAB guanine nucleotide exchange factor (GEF) 1 7 66682164-66811464 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001407 Supported Nucleoli
Cytosol Expressed in all bone marrow: 54.0 -MRPL39 C21orf92, FLJ20451, L39mt, MGC104174, MGC3400, MRP-L5, MSTP003, PRED22, PRED66, RPML5 ENSG00000154719 Mitochondrial ribosomal protein L39 21 25585656-25607517 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018331 Approved Expressed in all testis: 94.1 -JAM2 C21orf43, CD322, JAM-B, JAMB, VE-JAM ENSG00000154721 Junctional adhesion molecule 2 21 25639272-25717562 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046547 Approved Cytosol Tissue enhanced 0 placenta: 92.1 cerebral cortex: 34.3 -ATP5J ATP5, ATP5A, ATPM, CF6 ENSG00000154723 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 21 25716503-25735673 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031069 Supported Supported Mitochondria Expressed in all heart muscle: 542.4 -GABPA E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A ENSG00000154727 GA binding protein transcription factor, alpha subunit 60kDa 21 25734570-25772460 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003258, CAB004411, HPA028791 Supported Validated Nucleoplasm Expressed in all thyroid gland: 37.9 -ADAMTS1 C3-C5, KIAA1346, METH1 ENSG00000154734 ADAM metallopeptidase with thrombospondin type 1 motif, 1 21 26835747-26845409 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016394, HPA031498, HPA031499 Uncertain Validated Cytosol Tissue enhanced 0 ovary: 410.9 adipose tissue: 276.6 -ADAMTS5 ADAMTS11, ADMP-2 ENSG00000154736 ADAM metallopeptidase with thrombospondin type 1 motif, 5 21 26917912-26966513 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005661, CAB025996, HPA030906, HPA030908 Approved Supported Nucleoplasm Tissue enhanced 0 placenta: 42.0 ovary: 24.2 -TSEN2 MGC2776, SEN2, SEN2L ENSG00000154743 TSEN2 tRNA splicing endonuclease subunit 3 12484432-12539623 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027120, HPA027125, HPA027268 Approved Validated Nucleoplasm
Cytosol Expressed in all endometrium: 14.2 -SLFN13 FLJ31952 ENSG00000154760 Schlafen family member 13 17 35435096-35448837 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA022532, HPA023064 Uncertain Approved Cytokinetic bridge Mixed parathyroid gland: 40.4 -WNT7A ENSG00000154764 Wingless-type MMTV integration site family, member 7A 3 13816258-13880121 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA015719, CAB025894 Approved Tissue enhanced 0 cerebral cortex: 6.7;gallbladder: 3.7;placenta: 3.9 lung: 3.0 -XPC RAD4, XPCC ENSG00000154767 Xeroderma pigmentosum, complementation group C 3 14145147-14178783 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009932, HPA035707, HPA069673 Supported Validated Nucleus
Plasma membrane Expressed in all parathyroid gland: 51.3 -CCDC174 C3orf19, FLJ33839 ENSG00000154781 Coiled-coil domain containing 174 3 14651746-14672659 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043468, HPA060129 Approved Validated Nucleoplasm Expressed in all ovary: 17.9 -FGD5 FLJ00274, FLJ39957, ZFYVE23 ENSG00000154783 FYVE, RhoGEF and PH domain containing 5 3 14818962-14934565 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014536, HPA019191 Uncertain Mixed spleen: 31.9 -FLCN BHD, MGC17998, MGC23445 ENSG00000154803 Folliculin 17 17212212-17237188 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015158, HPA028760 Supported Supported Plasma membrane
Cytosol Expressed in all endometrium: 30.7 -DPH3 DELGIP, DELGIP1, DESR1, DPH3A, KTI11, MGC20197, ZCSL2 ENSG00000154813 Diphthamide biosynthesis 3 3 16257978-16264972 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035287 Uncertain Supported Nucleoplasm
Cytosol Expressed in all smooth muscle: 22.9 -OXNAD1 MGC15763 ENSG00000154814 Oxidoreductase NAD-binding domain containing 1 3 16265160-16350299 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036830, HPA059160 Approved Approved Nucleus Mixed lymph node: 19.9 -PLCL2 KIAA1092, PLCE2 ENSG00000154822 Phospholipase C-like 2 3 16802651-17090594 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047616 Uncertain Expressed in all ovary: 30.4 -CXXC1 CFP1, CGBP, hCGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1 ENSG00000154832 CXXC finger protein 1 18 50282343-50288304 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044511 Supported Validated Nucleus Expressed in all lymph node: 28.6 -SKA1 C18orf24, MGC10200 ENSG00000154839 Spindle and kinetochore associated complex subunit 1 18 50374995-50394173 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045495 Approved Supported Microtubules Tissue enhanced 0 testis: 5.9 bone marrow: 5.5 -PPP4R1 PP4R1 ENSG00000154845 Protein phosphatase 4, regulatory subunit 1 18 9546791-9615240 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040905, HPA041089 Uncertain Approved Nucleoplasm Expressed in all esophagus: 78.5 -APCDD1 B7323 ENSG00000154856 Adenomatosis polyposis coli down-regulated 1 18 10454628-10489948 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skin: 153.5 cerebral cortex: 60.8 -PIEZO2 C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771 ENSG00000154864 Piezo-type mechanosensitive ion channel component 2 18 10666483-11148762 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015986, HPA031974, HPA031975, HPA040616 Approved Approved Vesicles Mixed lung: 12.8 -MPPE1 ENSG00000154889 Metallophosphoesterase 1 18 11882622-11909223 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012639 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 77.6 -USP43 FLJ30626 ENSG00000154914 Ubiquitin specific peptidase 43 17 9644698-9729691 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023389, HPA027762 Uncertain Mixed placenta: 11.6 -RAB6B ENSG00000154917 RAB6B, member RAS oncogene family 3 133824239-133895836 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017713, HPA059131 Uncertain Approved Golgi apparatus Group enriched 6 cerebral cortex: 211.9;parathyroid gland: 75.7 fallopian tube: 25.9 -EME1 FLJ31364, MMS4L, SLX2A ENSG00000154920 Essential meiotic structure-specific endonuclease 1 17 50373220-50381483 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016127, HPA052188 Supported Approved Nuclear bodies
Cytosol Tissue enhanced 0 epididymis: 7.7;testis: 9.8 lymph node: 2.8 -EPHB1 EPHT2, Hek6 ENSG00000154928 EPH receptor B1 3 134597801-135260467 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067740 Approved Approved Endoplasmic reticulum
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 23.7;testis: 22.9 thyroid gland: 12.0 -ACSS1 ACAS2L, AceCS2L, dJ568C11.3, MGC33843 ENSG00000154930 Acyl-CoA synthetase short-chain family member 1 20 25006230-25058980 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041014, HPA043228 Approved Expressed in all placenta: 165.1 -ANKRD40 MGC15396 ENSG00000154945 Ankyrin repeat domain 40 17 50693190-50707924 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021668, HPA021759 Approved Approved Golgi apparatus
Cytosol Expressed in all cerebral cortex: 58.3 -ZNF18 HDSG1, KOX11, Zfp535, ZKSCAN6, ZNF535, ZSCAN38 ENSG00000154957 Zinc finger protein 18 17 11977439-11997510 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006144 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane
Cytosol Expressed in all testis: 22.2 -CA10 CA-RPX, CARPX, HUCEP-15 ENSG00000154975 Carbonic anhydrase X 17 51630313-52160017 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA054825, HPA057837 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 56.9;cervix, uterine: 31.9 testis: 10.6 -VOPP1 DKFZp564K0822, ECop, FLJ20532, GASP ENSG00000154978 Vesicular, overexpressed in cancer, prosurvival protein 1 7 55436056-55572988 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all lymph node: 111.8 -SEPT14 FLJ44060 ENSG00000154997 Septin 14 7 55793544-55862789 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA073255 Supported Tissue enriched 15 testis: 41.6 parathyroid gland: 2.8 -APOOL AAIR8193, CXorf33, FAM121A, Mic27, UNQ8193 ENSG00000155008 Apolipoprotein O-like X 85003826-85093316 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000612 Approved Approved Mitochondria Expressed in all parathyroid gland: 23.8 -DKK2 ENSG00000155011 Dickkopf WNT signaling pathway inhibitor 2 4 106921802-107283806 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB009727, HPA052611 Uncertain Uncertain Golgi apparatus Tissue enhanced 0 cervix, uterine: 23.9 lung: 8.2 -CYP2U1 SPG49 ENSG00000155016 Cytochrome P450, family 2, subfamily U, polypeptide 1 4 107931369-107953457 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041622, HPA046754, HPA064827 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Mixed prostate: 15.7 -RSPH10B ENSG00000155026 Radial spoke head 10 homolog B (Chlamydomonas) 7 5925550-5970683 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047076, HPA049181, HPA049182 Uncertain Group enriched 8 fallopian tube: 13.0;testis: 35.7 parathyroid gland: 2.9 -FBXL18 Fbl18, FLJ11467 ENSG00000155034 F-box and leucine-rich repeat protein 18 7 5431335-5513798 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036049 Approved Nucleoplasm
Cytosol Mixed cerebral cortex: 9.6 -CNTNAP5 caspr5, FLJ31966 ENSG00000155052 Contactin associated protein-like 5 2 124025287-124915287 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA069095, HPA069356 Supported Nucleus
Nucleoli fibrillar center
Vesicles Tissue enhanced 0 cerebral cortex: 5.8;gallbladder: 1.6 adrenal gland: 0.7 -PROM2 ENSG00000155066 Prominin 2 2 95274453-95291308 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046005, HPA063728 Supported Approved Nucleoplasm
Plasma membrane
Cell Junctions Tissue enhanced 0 skin: 71.3 esophagus: 44.8 -AK9 AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1, FLJ25791, FLJ42177, MGC26954 ENSG00000155085 Adenylate kinase 9 6 109492856-109691217 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030804, HPA030805, HPA031779, HPA031781, HPA036324, HPA036711 Approved Validated Nucleoplasm
Nuclear membrane Tissue enhanced 0 testis: 31.1 parathyroid gland: 16.8 -ODF1 CT133, HSPB10, ODF27, ODFPG, RT7 ENSG00000155087 Outer dense fiber of sperm tails 1 8 102551572-102561017 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064295 Approved Tissue enriched 1414 testis: 415.6 duodenum: 0.2 -KLF10 EGRA, TIEG, TIEG1 ENSG00000155090 Kruppel-like factor 10 8 102648779-102655902 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all lung: 100.0 -PTPRN2 IA-2beta, ICAAR, KIAA0387, phogrin ENSG00000155093 Protein tyrosine phosphatase, receptor type, N polypeptide 2 7 157539056-158587788 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006900, HPA026656 Approved Uncertain Vesicles
Plasma membrane Tissue enhanced 0 cerebral cortex: 82.5 stomach: 39.0 -AZIN1 OAZI, OAZIN, ODC1L ENSG00000155096 Antizyme inhibitor 1 8 102826357-102893864 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA027948 Approved Approved Vesicles Expressed in all cerebral cortex: 133.8 -ATP6V1C1 ATP6C, ATP6D, VATC, Vma5 ENSG00000155097 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 8 103021063-103073051 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023943, HPA057297 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 123.4 -TMEM55A DKFZp762O076 ENSG00000155099 Transmembrane protein 55A 8 90993796-91041064 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014591 Approved Mixed cerebral cortex: 21.8 -OTUD6B CGI-77, DUBA5 ENSG00000155100 OTU domain containing 6B 8 91070196-91087095 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024046, HPA024503, HPA024772 Approved Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Mixed cerebral cortex: 17.3 -CDK19 bA346C16.3, CDC2L6, CDK11, KIAA1028 ENSG00000155111 Cyclin-dependent kinase 19 6 110609978-110815958 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007053 Approved Approved Nucleoplasm
Vesicles Mixed prostate: 43.5 -GTF3C6 bA397G5.3, C6orf51, TFIIIC35 ENSG00000155115 General transcription factor IIIC, polypeptide 6, alpha 35kDa 6 110958560-110967890 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056179, HPA061345 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all prostate: 99.9 -TTC39B C9orf52, FLJ33868 ENSG00000155158 Tetratricopeptide repeat domain 39B 9 15163622-15307360 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054804, HPA063162 Uncertain Approved Endoplasmic reticulum Mixed gallbladder: 11.0 -AGPAT5 FLJ11210, LPAAT-e, LPAAT-epsilon ENSG00000155189 1-acylglycerol-3-phosphate O-acyltransferase 5 8 6708357-6759666 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010644, HPA010950 Approved Expressed in all testis: 46.7 -MMS19 hMMS19, MET18, MMS19L ENSG00000155229 MMS19 homolog, cytosolic iron-sulfur assembly component 10 97458324-97498794 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051936, HPA056299 Approved Validated Nucleoplasm Expressed in all testis: 52.6 -OR4K1 ENSG00000155249 Olfactory receptor, family 4, subfamily K, member 1 14 19935608-19936683 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA028877 Uncertain Not detected testis: 0.3 -PI4K2A DKFZP761G1923, PI4KII, PIK42A ENSG00000155252 Phosphatidylinositol 4-kinase type 2 alpha 10 97640686-97676434 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB030649, HPA076857 Approved Supported Plasma membrane Expressed in all parathyroid gland: 30.8 -MARVELD1 bA548K23.8, FLJ22343, FLJ23440, GB14, MGC4415, MRVLDC1 ENSG00000155254 MARVEL domain containing 1 10 97713173-97718152 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed smooth muscle: 68.4 -ZFYVE27 FLJ32919, SPG33 ENSG00000155256 Zinc finger, FYVE domain containing 27 10 97737121-97760907 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037523, HPA069876 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 33.4 -GOLGA7B bA451M19.3, bA459F3.4, C10orf132, C10orf133 ENSG00000155265 Golgin A7 family, member B 10 97850239-97871580 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046878 Uncertain Group enriched 7 cerebral cortex: 18.4;epididymis: 28.1;skin: 17.4 adrenal gland: 3.1 -GPR78 ENSG00000155269 G protein-coupled receptor 78 4 8558725-8619761 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA013209 Uncertain Not detected adipose tissue: 0.0 -TRMT44 C4orf23, FLJ35725, METTL19, TRM44 ENSG00000155275 TRNA methyltransferase 44 homolog (S. cerevisiae) 4 8436140-8493531 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045461 Uncertain Approved Nucleoplasm Mixed endometrium: 9.9 -SLC25A28 MRS3/4, MRS4L ENSG00000155287 Solute carrier family 25 (mitochondrial iron transporter), member 28 10 99610522-99620609 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Expressed in all testis: 93.2 -HSPA13 STCH ENSG00000155304 Heat shock protein 70kDa family, member 13 21 14371115-14383484 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014797 Approved Expressed in all cerebral cortex: 55.9 -SAMSN1 HACS1, NASH1, SASH2, SH3D6B, SLy2 ENSG00000155307 SAM domain, SH3 domain and nuclear localization signals 1 21 14485228-14583402 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010645, HPA017055 Approved Tissue enhanced 0 appendix: 112.6;bone marrow: 123.8 spleen: 44.2 -USP25 USP21 ENSG00000155313 Ubiquitin specific peptidase 25 21 15730025-15880069 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018297, HPA024142 Approved Supported Cytosol Expressed in all testis: 97.1 -GRAMD3 FLJ21313, NS3TP2 ENSG00000155324 GRAM domain containing 3 5 126360132-126496494 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009678, HPA010095 Supported Approved Nucleoplasm
Golgi apparatus
Cytosol Mixed thyroid gland: 68.7 -ZCCHC10 FLJ20094 ENSG00000155329 Zinc finger, CCHC domain containing 10 5 132996985-133026604 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038944 Approved Approved Nucleus
Nucleoli Expressed in all testis: 43.4 -C16orf87 ENSG00000155330 Chromosome 16 open reading frame 87 16 46796607-46831411 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041179 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 56.6 parathyroid gland: 34.0 -MOV10 fSAP113, gb110, MGC2948 ENSG00000155363 Mov10 RISC complex RNA helicase 1 112673141-112700746 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031627 Approved Cytosol Expressed in all placenta: 33.6 -RHOC ARH9, ARHC, RhoC ENSG00000155366 Ras homolog family member C 1 112701106-112707434 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051461 Uncertain Expressed in all parathyroid gland: 685.6 -PPM1J DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ ENSG00000155367 Protein phosphatase, Mg2+/Mn2+ dependent, 1J 1 112709994-112715477 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046045 Uncertain Approved Vesicles Group enriched 6 epididymis: 22.4;skeletal muscle: 24.1;skin: 21.4;testis: 46.4 heart muscle: 4.6 -DBI ACBD1, ACBP ENSG00000155368 Diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 2 119366921-119372560 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051428 Approved Expressed in all breast: 898.4 -SLC16A1 MCT, MCT1 ENSG00000155380 Solute carrier family 16 (monocarboxylate transporter), member 1 1 112911847-112957013 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003324, CAB017489, HPA071055 Supported Validated Plasma membrane
Cell Junctions Mixed testis: 32.0 -HEATR3 FLJ20718 ENSG00000155393 HEAT repeat containing 3 16 50065941-50106387 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041990, HPA058579 Uncertain Approved Nucleus
Cytosol Mixed appendix: 16.0 -TRIM74 MGC45440, TRIM50C ENSG00000155428 Tripartite motif containing 74 7 72959485-72969466 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047843 Uncertain Cytosol Tissue enhanced 0 stomach: 5.2 testis: 3.9 -NIFK hNIFK, MKI67IP, Nopp34 ENSG00000155438 Nucleolar protein interacting with the FHA domain of MKI67 2 121726945-121736923 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015382, HPA035735, HPA035736, CAB075728, CAB075729 Supported Validated Nucleoli Expressed in all lymph node: 50.3 -OXA1L MGC133129, OXA1 ENSG00000155463 Oxidase (cytochrome c) assembly 1-like 14 22766522-22773041 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003531 Approved Supported Mitochondria Expressed in all parathyroid gland: 139.8 -SLC7A7 LPI, y+LAT-1 ENSG00000155465 Solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 14 22773222-22829820 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036227 Approved Tissue enhanced 0 kidney: 279.7 parathyroid gland: 159.0 -MAGEC1 CT7, CT7.1, MAGE-C1, MGC39366 ENSG00000155495 Melanoma antigen family C1 X 141903894-141909388 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004622, CAB015452 Supported Approved Nucleoplasm
Cytosol Tissue enriched 133 testis: 13.3 epididymis: 0.0 -LARP1 KIAA0731, LARP, MGC19556 ENSG00000155506 La ribonucleoprotein domain family, member 1 5 154712902-154817607 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015222, HPA051397, HPA054819 Supported Supported Nucleus
Endoplasmic reticulum
Cytosol Expressed in all parathyroid gland: 150.6 -CNOT8 CAF1, CALIF, hCAF1, POP2 ENSG00000155508 CCR4-NOT transcription complex, subunit 8 5 154857553-154876793 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051398 Approved Expressed in all bone marrow: 74.8 -GRIA1 GluA1, GLUR1, GLURA ENSG00000155511 Glutamate receptor, ionotropic, AMPA 1 5 153489615-153813869 FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001965, HPA035202 Supported Tissue enriched 6 cerebral cortex: 67.3 lung: 10.6 -LRGUK CFAP246, FLJ32786 ENSG00000155530 Leucine-rich repeats and guanylate kinase domain containing 7 134127299-134264591 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029505, HPA029506 Uncertain Group enriched 8 epididymis: 1.7;fallopian tube: 5.4;testis: 8.3 thyroid gland: 0.6 -SETD9 C5orf35, MGC33648 ENSG00000155542 SET domain containing 9 5 56909260-56925532 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049936 Approved Nucleoplasm Tissue enriched 6 testis: 27.0 thyroid gland: 4.3 -MIER3 DKFZp686L09111, DKFZp781I1119, FLJ35954 ENSG00000155545 Mesoderm induction early response 1, family member 3 5 56919602-56971675 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058349, HPA065946 Uncertain Validated Nucleoplasm Expressed in all colon: 30.7 -NUP205 C7orf14, KIAA0225 ENSG00000155561 Nucleoporin 205kDa 7 135557919-135648757 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024574 Uncertain Expressed in all parathyroid gland: 29.7 -ZKSCAN2 FLJ23199, ZNF694, ZSCAN34 ENSG00000155592 Zinc finger with KRAB and SCAN domains 2 16 25236001-25257931 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049141 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus Mixed testis: 7.6 -C9orf85 MGC61599 ENSG00000155621 Chromosome 9 open reading frame 85 9 71911510-71986054 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA050767 Approved Nucleus
Nucleoli
Golgi apparatus Expressed in all thyroid gland: 13.9 -XAGE2 CT12.2, GAGED3, XAGE-2, XAGE2B ENSG00000155622 X antigen family, member 2 X 52369030-52375680 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA052507, HPA060900 Supported Tissue enriched 35 placenta: 292.4 lung: 8.4 -PIK3AP1 BCAP, FLJ35564 ENSG00000155629 Phosphoinositide-3-kinase adaptor protein 1 10 96593312-96720514 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026136, HPA038452 Supported Approved Nucleus
Plasma membrane
Cytosol Tissue enhanced 0 spleen: 86.8 lymph node: 72.8 -RBM45 DRB1, FLJ44612 ENSG00000155636 RNA binding motif protein 45 2 178112424-178139011 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020448 Approved Supported Nucleus Expressed in all parathyroid gland: 12.1 -C10orf12 DKFZP564P1916, FLJ13022 ENSG00000155640 Chromosome 10 open reading frame 12 10 96981284-96986212 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038954 Approved Approved Nucleoplasm
Endoplasmic reticulum Mixed bone marrow: 4.7 -TTN CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD ENSG00000155657 Titin 2 178525989-178830802 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007042, CAB022682 Supported Tissue enriched 8 skeletal muscle: 322.6 heart muscle: 42.7 -VSIG4 Z39IG ENSG00000155659 V-set and immunoglobulin domain containing 4 X 66021738-66040125 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003903, CAB026000 Approved Uncertain Nucleoli
Plasma membrane
Cytosol Expressed in all lung: 243.3 -PDIA4 ERP70, ERP72 ENSG00000155660 Protein disulfide isomerase family A, member 4 7 149003062-149028641 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006139, HPA006140, CAB017368 Supported Supported Endoplasmic reticulum Expressed in all thyroid gland: 371.2 -KDM8 FLJ13798, JMJD5 ENSG00000155666 Lysine (K)-specific demethylase 8 16 27203495-27221768 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026545 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 liver: 24.2 small intestine: 14.1 -PDZD9 C16orf65, MGC50721 ENSG00000155714 PDZ domain containing 9 16 21983865-22001110 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 39 testis: 20.7 cerebral cortex: 0.5 -OTOA CT108, DFNB22 ENSG00000155719 Otoancorin 16 21678514-21760729 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041405 Uncertain Group enriched 14 spleen: 2.7;testis: 6.2 epididymis: 0.3 -KCTD18 6530404F10Rik, FLJ31322, FLJ37818 ENSG00000155729 Potassium channel tetramerization domain containing 18 2 200488952-200519784 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045498, HPA058028 Approved Approved Mitochondria Expressed in all thyroid gland: 23.1 -FAM126B HYCC2, MGC39518 ENSG00000155744 Family with sequence similarity 126, member B 2 200973718-201071671 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036166, HPA036167, HPA067307 Uncertain Supported Nucleus
Cell Junctions Mixed cerebral cortex: 15.0 -ALS2CR12 ENSG00000155749 Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 2 201288271-201357398 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035793 Uncertain Approved Plasma membrane
Cytosol Group enriched 5 fallopian tube: 15.1;testis: 31.7 lung: 4.3 -ALS2CR11 FLJ25351 ENSG00000155754 Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 2 201487425-201619178 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 77 testis: 73.8 ovary: 0.9 -TMEM237 ALS2CR4, JBTS14 ENSG00000155755 Transmembrane protein 237 2 201620184-201643570 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052596, HPA054732 Supported Mixed skin: 21.9 -FZD7 FzE3 ENSG00000155760 Frizzled class receptor 7 2 202034587-202038445 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069165 Approved Nucleoplasm Mixed seminal vesicle: 38.7 -SPAG17 CT143, FLJ34497, PF6, RP4-776P7.2 ENSG00000155761 Sperm associated antigen 17 1 117953861-118185223 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028597, HPA028666 Supported Validated Nucleoplasm Tissue enhanced 0 fallopian tube: 13.2;testis: 27.4 esophagus: 6.8 -DEPTOR DEP.6, DEPDC6, FLJ12428 ENSG00000155792 DEP domain containing MTOR-interacting protein 8 119873717-120050913 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020841, HPA023938, HPA023945, HPA024011 Supported Approved Nucleoplasm
Mitochondria Expressed in all thyroid gland: 163.3 -FMN2 ENSG00000155816 Formin 2 1 240014348-240475189 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050649 Approved Plasma membrane
Actin filaments Group enriched 6 cerebral cortex: 54.0;parathyroid gland: 32.9 adrenal gland: 7.0 -RNF20 BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779 ENSG00000155827 Ring finger protein 20, E3 ubiquitin protein ligase 9 101533851-101563344 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012478, HPA051773 Supported Validated Nucleoplasm Expressed in all testis: 59.0 -CYLC2 ENSG00000155833 Cylicin, basic protein of sperm head cytoskeleton 2 9 102995311-103018488 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 395 testis: 79.9 epididymis: 0.2 -PPARGC1B PERC, PGC1B ENSG00000155846 Peroxisome proliferator-activated receptor gamma, coactivator 1 beta 5 149730298-149855022 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA050543 Supported Nucleus Mixed parathyroid gland: 14.8 -ELMO1 CED-12, CED12, ELMO-1, KIAA0281 ENSG00000155849 Engulfment and cell motility 1 7 36854361-37449249 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 137.2 -SLC26A2 DTD, DTDST ENSG00000155850 Solute carrier family 26 (anion exchanger), member 2 5 149960737-149993455 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041957, HPA058090 Supported Approved Vesicles Tissue enhanced 0 colon: 215.9;rectum: 209.8 parathyroid gland: 81.4 -LSM11 FLJ38273 ENSG00000155858 LSM11, U7 small nuclear RNA associated 5 157743695-157760709 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039587 Uncertain Supported Nucleus
Nuclear bodies Mixed cerebral cortex: 8.6 -MED7 CRSP33, CRSP9 ENSG00000155868 Mediator complex subunit 7 5 157137412-157159019 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067181 Supported Nuclear bodies Expressed in all testis: 46.4 -SAXO1 C9orf138, FAM154A, MGC35182 ENSG00000155875 Stabilizer of axonemal microtubules 1 9 18927658-19049354 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023899 Supported Tissue enriched 111 testis: 58.1 epididymis: 0.5 -RRAGA FIP-1, RAGA ENSG00000155876 Ras-related GTP binding A 9 19049395-19050983 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003734 Supported Approved Golgi apparatus
Vesicles Expressed in all cerebral cortex: 128.4 -SLC24A2 NCKX2 ENSG00000155886 Solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 9 19507452-19786928 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 cerebral cortex: 51.8 adrenal gland: 7.9 -TRIM42 FLJ40097, PPP1R40, T4A1 ENSG00000155890 Tripartite motif containing 42 3 140678039-140701150 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003581, HPA022481 Uncertain Nucleoplasm
Mitochondria Tissue enriched 292 testis: 29.1 epididymis: 0.0 -PXYLP1 ACPL2, FLJ23751 ENSG00000155893 2-phosphoxylose phosphatase 1 3 141228726-141294906 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017243 Approved Expressed in all epididymis: 178.7 -ADCY8 AC8, ADCY3, HBAC1 ENSG00000155897 Adenylate cyclase 8 (brain) 8 130780301-131042426 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018652, HPA024291 Supported Group enriched 8 cerebral cortex: 12.9;epididymis: 27.3;fallopian tube: 6.2 seminal vesicle: 1.9 -RASA2 GAP1M ENSG00000155903 RAS p21 protein activator 2 3 141487047-141615342 Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035374, HPA035375 Approved Approved Vesicles Mixed lymph node: 25.3 -RMND1 bA351K16.3, C6orf96, FLJ20627, RMD1 ENSG00000155906 Required for meiotic nuclear division 1 homolog 6 151404763-151452181 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031397, HPA031398, HPA031399 Approved Supported Mitochondria Expressed in all kidney: 43.8 -RAET1L ENSG00000155918 Retinoic acid early transcript 1L 6 150018334-150025532 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 esophagus: 39.1 tonsil: 6.1 -SLA SLA1 ENSG00000155926 Src-like-adaptor 8 133036724-133103054 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012296, HPA074192 Approved Approved Nuclear membrane Tissue enhanced 0 appendix: 107.0 lymph node: 80.8 -TMBIM4 CGI-119, GAAP, LFG4, S1R, ZPRO ENSG00000155957 Transmembrane BAX inhibitor motif containing 4 12 66135846-66170072 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA077642 Supported Golgi apparatus Expressed in all thyroid gland: 164.8 -VBP1 PFD3, PFDN3 ENSG00000155959 Von Hippel-Lindau binding protein 1 X 155197007-155239817 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006260, HPA023230 Approved Supported Vesicles
Cytosol Expressed in all cerebral cortex: 85.5 -RAB39B MRX72 ENSG00000155961 RAB39B, member RAS oncogene family X 155258241-155264589 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001114, HPA042505 Approved Tissue enhanced 0 cerebral cortex: 19.5 epididymis: 7.4 -CLIC2 XAP121 ENSG00000155962 Chloride intracellular channel 2 X 155276211-155334657 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047381, HPA060101 Uncertain Approved Plasma membrane Mixed spleen: 63.7 -AFF2 FMR2, FRAXE ENSG00000155966 AF4/FMR2 family, member 2 X 148500619-149000663 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003139 Approved Tissue enhanced 0 epididymis: 14.2;placenta: 20.9 bone marrow: 8.3 -MICU3 DKFZp313A0139, EFHA2 ENSG00000155970 Mitochondrial calcium uptake family, member 3 8 17027238-17122644 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024048, HPA024771, HPA024779 Uncertain Tissue enhanced 0 cerebral cortex: 34.9 parathyroid gland: 13.9 -GRIP1 ENSG00000155974 Glutamate receptor interacting protein 1 12 66347431-66804186 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038856 Uncertain Mixed seminal vesicle: 11.5 -VPS37A FLJ32642, HCRP1, PQBP2, SPG53 ENSG00000155975 Vacuolar protein sorting 37 homolog A (S. cerevisiae) 8 17246571-17302427 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024705, HPA024781 Supported Approved Vesicles
Centrosome
Cytosol Expressed in all testis: 57.1 -KIF5A D12S1889, MY050, NKHC, SPG10 ENSG00000155980 Kinesin family member 5A 12 57549998-57586632 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004469, CAB015157, HPA073448 Approved Approved Approved Nucleoplasm
Mitotic spindle
Cytosol Tissue enriched 28 cerebral cortex: 326.6 adrenal gland: 11.5 -NAT2 AAC2 ENSG00000156006 N-acetyltransferase 2 (arylamine N-acetyltransferase) 8 18391245-18401218 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043704 Uncertain Group enriched 13 colon: 14.7;duodenum: 33.6;liver: 62.2;rectum: 14.2;small intestine: 27.7 smooth muscle: 2.3 -MAGEA8 CT1.8, MAGE8, MGC2182 ENSG00000156009 Melanoma antigen family A8 X 149881141-149885835 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA003998 Supported Tissue enriched 9 placenta: 18.8 testis: 2.0 -PSD3 DKFZp761K1423, EFA6D, EFA6R, HCA67, KIAA0942 ENSG00000156011 Pleckstrin and Sec7 domain containing 3 8 18527301-19084730 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002455 Approved Nucleus
Vesicles Tissue enhanced 0 cerebral cortex: 83.5 testis: 29.5 -CARNMT1 C9orf41, FLJ25795 ENSG00000156017 Carnosine N-methyltransferase 1 9 74981020-75028423 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026756 Uncertain Expressed in all testis: 29.9 -MCU C10orf42, CCDC109A, FLJ46135 ENSG00000156026 Mitochondrial calcium uniporter 10 72692131-72887694 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016480 Approved Supported Mitochondria Expressed in all stomach: 41.1 -ELMSAN1 C14orf117, C14orf43, LSR68 ENSG00000156030 ELM2 and Myb/SANT-like domain containing 1 14 73715122-73790285 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003111 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 21.8 -CFAP70 FLJ25765, TTC18 ENSG00000156042 Cilia and flagella associated protein 70 10 73253759-73358859 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037582 Approved Tissue enhanced 0 fallopian tube: 23.4;testis: 38.3 epididymis: 14.3 -GNA14 ENSG00000156049 Guanine nucleotide binding protein (G protein), alpha 14 9 77423079-77648307 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048886 Approved Mixed thyroid gland: 29.7 -FAM161B C14orf44, FLJ31697 ENSG00000156050 Family with sequence similarity 161, member B 14 73931501-73950414 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA019125 Approved Mixed testis: 19.2 -GNAQ G-ALPHA-q, GAQ ENSG00000156052 Guanine nucleotide binding protein (G protein), q polypeptide 9 77716087-78031458 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010036, HPA048886 Uncertain Approved Nuclear speckles
Plasma membrane
Cytosol Expressed in all cerebral cortex: 85.1 -WIF1 ENSG00000156076 WNT inhibitory factor 1 12 65050626-65121566 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039104 Approved Tissue enriched 6 lung: 159.7 cerebral cortex: 26.5 -UGT2B4 UGT2B11 ENSG00000156096 UDP glucuronosyltransferase 2 family, polypeptide B4 4 69480165-69526014 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033260, HPA045108 Supported Tissue enriched 71 liver: 652.2 heart muscle: 9.2 -GPR61 BALGR ENSG00000156097 G protein-coupled receptor 61 1 109539872-109548406 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA007326, HPA026088 Approved Tissue enhanced 0 cerebral cortex: 3.4;thyroid gland: 1.2 adrenal gland: 1.0 -MMP16 C8orf57, DKFZp761D112, MT3-MMP ENSG00000156103 Matrix metallopeptidase 16 (membrane-inserted) 8 88032009-88328025 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA023693 Uncertain Approved Vesicles
Cytosol Tissue enhanced 0 cerebral cortex: 9.6 gallbladder: 4.2 -ADK AK ENSG00000156110 Adenosine kinase 10 74151185-74709303 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032876, HPA038391, HPA038409 Approved Supported Nucleoplasm
Cytosol Expressed in all liver: 77.4 -KCNMA1 KCa1.1, mSLO1, SLO ENSG00000156113 Potassium channel, calcium activated large conductance subfamily M alpha, member 1 10 76869601-77638595 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054648 Approved Tissue enhanced 0 smooth muscle: 147.6 endometrium: 122.5 -BATF B-ATF, BATF1, SFA-2 ENSG00000156127 Basic leucine zipper transcription factor, ATF-like 14 75522425-75547015 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059588, HPA064962 Approved Validated Nucleoplasm Tissue enhanced 0 lymph node: 31.9 appendix: 27.3 -DCK ENSG00000156136 Deoxycytidine kinase 4 70992538-71030914 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059609, HPA062773 Approved Supported Nucleus Expressed in all lymph node: 95.0 -ADAMTS3 ADAMTS-4, KIAA0366 ENSG00000156140 ADAM metallopeptidase with thrombospondin type 1 motif, 3 4 72280969-72568799 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021368, HPA021369 Uncertain Approved Intermediate filaments Tissue enhanced 0 parathyroid gland: 7.9 testis: 3.7 -ALX3 FND ENSG00000156150 ALX homeobox 3 1 110059994-110070700 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed skin: 7.7 -DPY19L4 ENSG00000156162 Dpy-19-like 4 (C. elegans) 8 94719703-94793836 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024780 Approved Approved Vesicles Expressed in all parathyroid gland: 36.2 -NDUFAF6 C8orf38, MGC40214 ENSG00000156170 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 8 94895767-95116455 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047148, HPA050545 Approved Mixed thyroid gland: 10.5 -DRAM2 MGC54289, PRO180, RP5-1180E21.1, TMEM77, WWFQ154 ENSG00000156171 DNA-damage regulated autophagy modulator 2 1 111117333-111140216 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018036, HPA061701 Supported Validated Golgi apparatus
Vesicles Mixed spleen: 19.8 -C8orf37 CORD16, FLJ30600, RP64 ENSG00000156172 Chromosome 8 open reading frame 37 8 95244919-95269201 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024198 Approved Approved Plasma membrane
Cell Junctions
Cytosol Mixed fallopian tube: 6.3 -PPEF2 PPP7CB ENSG00000156194 Protein phosphatase, EF-hand calcium binding domain 2 4 75859864-75902571 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected testis: 0.3 -CFAP161 C15orf26, FLJ38615 ENSG00000156206 Cilia and flagella associated protein 161 15 81007033-81149175 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041807 Uncertain Tissue enhanced 0 fallopian tube: 24.5;testis: 11.4 lung: 4.1 -ADAMTSL3 KIAA1233, punctin-2 ENSG00000156218 ADAMTS-like 3 15 83654086-84039842 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034773, HPA034774 Approved Approved Vesicles Mixed placenta: 14.7 -ART3 ENSG00000156219 ADP-ribosyltransferase 3 4 76011184-76112802 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011268 Supported Tissue enhanced 0 skeletal muscle: 77.0;testis: 173.4 heart muscle: 33.4 -SLC28A1 CNT1 ENSG00000156222 Solute carrier family 28 (concentrative nucleoside transporter), member 1 15 84884654-84945796 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019551 Supported Group enriched 26 duodenum: 39.0;kidney: 49.1;liver: 35.4;small intestine: 54.7 placenta: 1.6 -WHAMM KIAA1971, WHAMM1, WHDC1 ENSG00000156232 WAS protein homolog associated with actin, golgi membranes and microtubules 15 82809628-82836108 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039690, HPA040231 Supported Supported Cytosol Expressed in all bone marrow: 19.0 -CXCL13 ANGIE, ANGIE2, BCA-1, BLC, BLR1L, SCYB13 ENSG00000156234 Chemokine (C-X-C motif) ligand 13 4 77511753-77611834 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052613 Uncertain Group enriched 7 appendix: 170.3;lymph node: 606.7;spleen: 430.3;tonsil: 411.9 urinary bladder: 60.1 -N6AMT1 C21orf127, HEMK2, MTQ2, N6AMT, PRED28 ENSG00000156239 N-6 adenine-specific DNA methyltransferase 1 (putative) 21 28872191-28885371 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034133, CAB034135, HPA059242 Approved Approved Nucleoplasm
Centrosome Mixed parathyroid gland: 11.3 -RWDD2B C21orf6, GL011 ENSG00000156253 RWD domain containing 2B 21 29004384-29019378 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018316 Uncertain Mixed thyroid gland: 1.9 -USP16 Ubp-M ENSG00000156256 Ubiquitin specific peptidase 16 21 29024629-29054488 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021140 Supported Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 56.2 -CCT8 C21orf112, Cctq, PRED71 ENSG00000156261 Chaperonin containing TCP1, subunit 8 (theta) 21 29055805-29073797 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018520, HPA021051, HPA029426 Supported Approved Nucleus
Intermediate filaments
Cytosol Expressed in all lymph node: 137.5 -MAP3K7CL C21orf7, TAK1L, TAKL, TAKL-1, TAKL-2, TAKL-4 ENSG00000156265 MAP3K7 C-terminal like 21 29077471-29175889 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA030079, HPA042439 Uncertain Approved Nucleoplasm Mixed heart muscle: 14.7 -NAA11 ARD1B, ARD2, hARD2 ENSG00000156269 N(alpha)-acetyltransferase 11, NatA catalytic subunit 4 79225694-79326050 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035922 Approved Group enriched 38 placenta: 6.1;testis: 11.4 parathyroid gland: 0.2 -BACH1 BACH-1, BTBD24 ENSG00000156273 BTB and CNC homology 1, basic leucine zipper transcription factor 1 21 29194071-29630751 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034949 Approved Nucleus
Cytosol Expressed in all placenta: 71.6 -CLDN17 MGC126552, MGC126554 ENSG00000156282 Claudin 17 21 30165564-30166756 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA045903 Supported Tissue enriched 5 esophagus: 6.6 tonsil: 1.3 -CLDN8 ENSG00000156284 Claudin 8 21 30214006-30216073 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA060605 Approved Tissue enhanced 0 breast: 84.5;kidney: 75.5;rectum: 56.8 thyroid gland: 37.2 -TSPAN7 A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2 ENSG00000156298 Tetraspanin 7 X 38561370-38688920 CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003140, CAB062566, CAB068245 Supported Tissue enriched 6 cerebral cortex: 576.3 adrenal gland: 99.7 -TIAM1 ENSG00000156299 T-cell lymphoma invasion and metastasis 1 21 31118416-31559977 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010416, HPA034853 Uncertain Approved Nucleoplasm
Nuclear membrane
Cell Junctions
Cytosol Mixed esophagus: 21.6 -SCAF4 DKFZp434E098, KIAA1172, SFRS15, SRA4 ENSG00000156304 SR-related CTD-associated factor 4 21 31671033-31732075 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018319, HPA018668, HPA021504, HPA028807 Supported Validated Nucleoplasm Expressed in all testis: 28.4 -RPGR COD1, CORDX1, CRD, RP15, RP3 ENSG00000156313 Retinitis pigmentosa GTPase regulator X 38269163-38327564 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001593, HPA073455 Uncertain Supported Golgi apparatus Expressed in all fallopian tube: 23.0 -CDK20 CCRK, p42 ENSG00000156345 Cyclin-dependent kinase 20 9 87966441-87974753 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA007666, HPA027379, HPA027401 Approved Supported Nucleoplasm Mixed fallopian tube: 20.5 -PCGF6 MBLR, RNF134 ENSG00000156374 Polycomb group ring finger 6 10 103302796-103351134 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 16.2 -ANKRD9 ENSG00000156381 Ankyrin repeat domain 9 14 102501760-102509799 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055985 Uncertain Expressed in all duodenum: 51.8 -SFR1 bA373N18.1, C10orf78, FLJ41960, MEI5, MEIR5 ENSG00000156384 SWI5-dependent homologous recombination repair protein 1 10 104122058-104126385 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039617 Uncertain Expressed in all testis: 32.9 -SORCS3 KIAA1059, SORCS ENSG00000156395 Sortilin-related VPS10 domain containing receptor 3 10 104641101-105265235 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 11.9 adrenal gland: 2.6 -SFXN2 ENSG00000156398 Sideroflexin 2 10 102714538-102743492 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018150, HPA026834 Supported Approved Mitochondria Tissue enhanced 0 kidney: 18.8 parathyroid gland: 13.2 -C14orf2 MP68 ENSG00000156411 Chromosome 14 open reading frame 2 14 103912288-103928269 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058978, HPA060520 Supported Supported Nucleoli fibrillar center
Mitochondria Expressed in all heart muscle: 206.9 -FUT6 FCT3A, FLJ40754, FT1A, FucT-VI ENSG00000156413 Fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 19 5830610-5839731 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043707, HPA046966 Approved Supported Golgi apparatus Tissue enhanced 0 esophagus: 50.0;kidney: 34.3 small intestine: 31.2 -TDRD9 C14orf75, DKFZp434N0820, FLJ36164, NET54 ENSG00000156414 Tudor domain containing 9 14 103928462-104052667 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 6 parathyroid gland: 39.0;testis: 74.7 thyroid gland: 9.1 -FGF18 FGF-18, ZFGF5 ENSG00000156427 Fibroblast growth factor 18 5 171419656-171457623 Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA018795 Uncertain Tissue enhanced 0 heart muscle: 5.4 lung: 1.9 -PCDH1 pc42 ENSG00000156453 Protocadherin 1 5 141853111-141879246 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047720, HPA050538 Approved Approved Nucleus
Nucleoli
Cell Junctions Mixed cerebral cortex: 40.4 -SH3RF2 FLJ23654, Hepp1, POSHER, PPP1R39, RNF158 ENSG00000156463 SH3 domain containing ring finger 2 5 145936579-146081791 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035903, HPA058119 Uncertain Approved Nucleoplasm Tissue enhanced 0 skin: 67.4 heart muscle: 26.1 -GDF6 BMP13, KFS, KFS1, SGM1 ENSG00000156466 Growth differentiation factor 6 8 96142330-96160792 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045206 Uncertain Tissue enhanced 0 placenta: 15.0 gallbladder: 3.8 -UQCRB QCR7, QP-C, UQBP, UQCR6 ENSG00000156467 Ubiquinol-cytochrome c reductase binding protein 8 96225920-96235634 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043060 Approved Expressed in all heart muscle: 506.1 -MTERF3 CGI-12, FLJ10939, MTERFD1 ENSG00000156469 Mitochondrial transcription termination factor 3 8 96239398-96261610 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002966 Supported Nucleoplasm
Mitochondria Expressed in all parathyroid gland: 29.8 -PTDSS1 KIAA0024, PSS1, PSSA ENSG00000156471 Phosphatidylserine synthase 1 8 96261715-96336995 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016852 Uncertain Approved Nucleoplasm
Endoplasmic reticulum Mixed parathyroid gland: 13.9 -PPP2R2B PR52B, PR55-BETA, SCA12 ENSG00000156475 Protein phosphatase 2, regulatory subunit B, beta 5 146581146-147084784 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038118, HPA042122, HPA042770 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 135.6 testis: 33.7 -RPL30 L30 ENSG00000156482 Ribosomal protein L30 8 98024851-98046469 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002651 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all ovary: 5893.2 -KCNS2 Kv9.2 ENSG00000156486 Potassium voltage-gated channel, modifier subfamily S, member 2 8 98427022-98432848 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA051417 Uncertain Tissue enhanced 0 cerebral cortex: 7.2 placenta: 2.2 -FAM122C RP3-473B4.1 ENSG00000156500 Family with sequence similarity 122C X 134796789-134854610 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059961 Approved Uncertain Nucleoplasm Mixed testis: 7.8 -SUPV3L1 SUV3 ENSG00000156502 SUV3-like helicase 10 69180232-69209099 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038380, HPA038405 Supported Supported Mitochondria Expressed in all testis: 28.9 -FAM122B DKFZp686L20116, RP11-308B5.5 ENSG00000156504 Family with sequence similarity 122B X 134769566-134797232 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000266 Approved Approved Nucleoplasm Expressed in all testis: 66.4 -EEF1A1 EE1A1, EEF1A, EF1A, LENG7 ENSG00000156508 Eukaryotic translation elongation factor 1 alpha 1 6 73515750-73523797 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051759, HPA053862, HPA056990 Supported Supported Cytosol Expressed in all ovary: 14688.0 -FBXO43 Fbx43 ENSG00000156509 F-box protein 43 8 100133360-100145800 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024292, HPA024295, HPA024824 Uncertain Tissue enriched 20 testis: 9.6 tonsil: 0.4 -HKDC1 FLJ22761, FLJ37767 ENSG00000156510 Hexokinase domain containing 1 10 69220303-69267559 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011956, HPA064198, HPA064230 Approved Validated Mitochondria Tissue enhanced 0 duodenum: 54.6;small intestine: 53.3 thyroid gland: 15.1 -HK1 ENSG00000156515 Hexokinase 1 10 69269984-69401882 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007043, HPA007044, CAB010052, HPA011956 Supported Validated Mitochondria Expressed in all testis: 152.9 -TYSND1 MGC34695, NET41 ENSG00000156521 Trypsin domain containing 1 10 70137981-70146676 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030304 Uncertain Uncertain Nucleoplasm
Centrosome
Cytosol Mixed adipose tissue: 5.8 -PHF6 BFLS, BORJ, CENP-31, KIAA1823, MGC14797 ENSG00000156531 PHD finger protein 6 X 134373253-134428791 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001023 Supported Validated Nucleus
Nucleoli Expressed in all parathyroid gland: 41.2 -CD109 CPAMD7, DKFZp762L1111, FLJ38569 ENSG00000156535 CD109 molecule 6 73695785-73828316 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009292, HPA015113 Approved Tissue enriched 42 parathyroid gland: 950.3 skin: 22.4 -LRFN2 FIGLER2, KIAA1246, SALM1 ENSG00000156564 Leucine rich repeat and fibronectin type III domain containing 2 6 40391586-40587465 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA013653, HPA076660 Uncertain Supported Vesicles Tissue enriched 5 cerebral cortex: 6.9 spleen: 1.3 -NODAL ENSG00000156574 Nodal growth differentiation factor 10 70432315-70447951 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045201 Uncertain Tissue enhanced 0 testis: 3.0 skin: 1.2 -PRG3 MBPH ENSG00000156575 Proteoglycan 3 11 57376769-57381150 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064183 Supported Tissue enriched 45 bone marrow: 29.4 spleen: 0.6 -UBE2L6 UBCH8 ENSG00000156587 Ubiquitin-conjugating enzyme E2L 6 11 57551656-57568284 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003328, CAB073407 Supported Approved Cytosol Expressed in all spleen: 150.4 -ZDHHC5 KIAA1748, ZNF375 ENSG00000156599 Zinc finger, DHHC-type containing 5 11 57667747-57701187 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014670 Approved Approved Nucleoplasm
Plasma membrane
Cell Junctions
Cytosol Expressed in all parathyroid gland: 86.1 -MED19 LCMR1 ENSG00000156603 Mediator complex subunit 19 11 57703714-57712221 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039912, HPA040860 Uncertain Supported Nucleus
Nuclear bodies Expressed in all testis: 30.8 -ZFAND3 FLJ13222, TEX27 ENSG00000156639 Zinc finger, AN1-type domain 3 6 37819499-38154624 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016755 Approved Approved Nucleoplasm
Vesicles Expressed in all testis: 184.1 -NPTN GP55, GP65, np55, np65, SDFR1, SDR1 ENSG00000156642 Neuroplastin 15 73560014-73634134 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051497, HPA072453 Approved Approved Cytokinetic bridge
Mitochondria Expressed in all smooth muscle: 428.0 -KAT6B Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B ENSG00000156650 K(lysine) acetyltransferase 6B 10 74825582-75032622 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006104 Supported Approved Nucleus
Nuclear bodies Expressed in all parathyroid gland: 17.0 -SAMD8 FLJ25082, SMSr ENSG00000156671 Sterile alpha motif domain containing 8 10 75099586-75182123 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044402 Supported Endoplasmic reticulum Expressed in all cerebral cortex: 43.2 -RAB11FIP1 FLJ22524, FLJ22622, Rab11-FIP1, RCP ENSG00000156675 RAB11 family interacting protein 1 (class I) 8 37858618-37899467 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017037, HPA023904, HPA024010, HPA025960 Supported Validated Vesicles Expressed in all lung: 112.0 -UNC5D KIAA1777, Unc5h4 ENSG00000156687 Unc-5 netrin receptor D 8 35235457-35796550 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042940 Uncertain Tissue enhanced 0 cerebral cortex: 9.2;duodenum: 6.2;prostate: 9.0 cervix: 3.4 -GLYATL2 BXMAS2-10, MGC24009 ENSG00000156689 Glycine-N-acyltransferase-like 2 11 58834065-58904215 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060292, HPA065454 Uncertain Approved Mitochondria Group enriched 6 breast: 14.1;cervix, uterine: 27.3;gallbladder: 11.0 salivary gland: 3.0 -UTP14A NY-CO-16, SDCCAG16 ENSG00000156697 UTP14A small subunit (SSU) processome component X 129906121-129929761 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047217, HPA054023 Uncertain Supported Nucleoli
Cytosol Expressed in all endometrium: 18.4 -AIFM1 AIF, CMTX4, NAMSD, PDCD8 ENSG00000156709 Apoptosis-inducing factor, mitochondrion-associated, 1 X 130129362-130165887 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003764, HPA030611 Supported Expressed in all kidney: 156.9 -MAPK13 p38delta, PRKM13, SAPK4 ENSG00000156711 Mitogen-activated protein kinase 13 6 36127809-36144524 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007667, CAB025854 Approved Approved Nucleus
Nucleoli
Cytosol Mixed skin: 93.9 -BAG4 SODD ENSG00000156735 BCL2-associated athanogene 4 8 38176533-38213301 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013716, HPA018951 Approved Expressed in all cerebral cortex: 27.2 -MS4A1 B1, Bp35, CD20, MS4A2 ENSG00000156738 Membrane-spanning 4-domains, subfamily A, member 1 11 60455752-60470760 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000015, HPA014341, HPA014391 Supported Group enriched 15 appendix: 249.3;lymph node: 780.6;spleen: 476.2;tonsil: 821.5 urinary bladder: 39.8 -TBC1D31 Gm85, MGC21654, WDR67 ENSG00000156787 TBC1 domain family, member 31 8 123041968-123152153 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023710 Approved Approved Centrosome Mixed testis: 8.4 -WDYHV1 C8orf32, FLJ10204 ENSG00000156795 WDYHV motif containing 1 8 123416725-123467230 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024823, HPA053680 Approved Supported Nucleoplasm
Vesicles Expressed in all testis: 18.4 -ATAD2 CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000 ENSG00000156802 ATPase family, AAA domain containing 2 8 123319850-123416350 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029424, CAB056158 Supported Validated Nucleoplasm Mixed testis: 34.3 -FBXO32 ATROGIN1, Fbx32, MAFbx ENSG00000156804 F-box protein 32 8 123497889-123541206 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA065209 Supported Nucleoplasm
Cytosol Tissue enhanced 0 smooth muscle: 144.9 skeletal muscle: 88.7 -NSMCE2 C8orf36, FLJ32440, MMS21, NSE2, ZMIZ7 ENSG00000156831 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase 8 125091679-125367120 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051614, HPA065734 Supported Supported Nucleus
Nuclear bodies Expressed in all thyroid gland: 29.9 -ZNF689 FLJ90415 ENSG00000156853 Zinc finger protein 689 16 30602558-30624012 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054095, HPA055385 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all testis: 35.3 -PRR14 MGC3121 ENSG00000156858 Proline rich 14 16 30650717-30656440 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052022, HPA060265 Uncertain Approved Nucleoplasm Expressed in all spleen: 20.3 -FBRS FBS, FBS1, FLJ11618 ENSG00000156860 Fibrosin 16 30658431-30670814 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044117 Approved Approved Nucleoplasm Expressed in all testis: 78.2 -FRRS1 SDFR2, SDR2 ENSG00000156869 Ferric-chelate reductase 1 1 99708703-99766631 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA017883 Approved Mixed placenta: 15.7 -PHKG2 ENSG00000156873 Phosphorylase kinase, gamma 2 (testis) 16 30748270-30761176 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065618, HPA068751 Supported Cytosol Expressed in all testis: 149.6 -HIAT1 DKFZP564L0864 ENSG00000156875 Hippocampus abundant transcript 1 1 100038097-100083377 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA073681 Approved Vesicles Expressed in all parathyroid gland: 197.2 -SASS6 DKFZp761A078, FLJ22097, SAS-6, SAS6 ENSG00000156876 SAS-6 centriolar assembly protein 1 100083563-100132955 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028187 Uncertain Supported Microtubule organizing center
Cytosol Mixed testis: 13.3 -COX6A2 ENSG00000156885 Cytochrome c oxidase subunit VIa polypeptide 2 16 31427731-31428428 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 23 heart muscle: 681.3;skeletal muscle: 1847.0 esophagus: 55.1 -ITGAD ADB2, CD11d ENSG00000156886 Integrin, alpha D 16 31393312-31426505 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA026786 Uncertain Tissue enriched 5 spleen: 28.4 lymph node: 5.1 -ADGRG4 GPR112, PGR17, RP1-299I16 ENSG00000156920 Adhesion G protein-coupled receptor G4 X 136300963-136416888 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035324 Uncertain Tissue enhanced 0 duodenum: 2.6;small intestine: 1.7 fallopian tube: 0.5 -ZIC3 HTX, HTX1, ZNF203 ENSG00000156925 Zic family member 3 X 137566142-137577691 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047934, HPA052936 Approved Supported Nucleoplasm Tissue enhanced 0 cerebral cortex: 1.6;testis: 1.3 epididymis: 0.3 -MALSU1 C7orf30, mtRsfA ENSG00000156928 Mitochondrial assembly of ribosomal large subunit 1 7 23298739-23311729 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020487, HPA052210 Approved Validated Mitochondria Mixed placenta: 6.4 -VPS8 FLJ32099, KIAA0804 ENSG00000156931 Vacuolar protein sorting 8 homolog (S. cerevisiae) 3 184812143-185052614 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036871 Uncertain Approved Plasma membrane
Cytosol Expressed in all testis: 31.0 -GALK2 GK2 ENSG00000156958 Galactokinase 2 15 49155656-49367869 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043564, HPA048267 Uncertain Approved Nucleoplasm
Cytosol Expressed in all kidney: 31.7 -LHFPL4 ENSG00000156959 Lipoma HMGIC fusion partner-like 4 3 9498361-9553802 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041421 Uncertain Approved Nucleus
Golgi apparatus Tissue enriched 9 cerebral cortex: 23.1 adrenal gland: 2.6 -B3GNT7 beta3GnT7 ENSG00000156966 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 2 231395543-231401164 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035625, HPA035626 Supported Tissue enhanced 0 rectum: 74.0 colon: 55.3 -MPV17L FLJ39599, MLPH1, MLPH2, MPV17L1 ENSG00000156968 MPV17 mitochondrial membrane protein-like 16 15395754-15413268 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041180 Uncertain Supported Vesicles Mixed breast: 11.4 -BUB1B Bub1A, BUBR1, MAD3L, SSK1 ENSG00000156970 BUB1 mitotic checkpoint serine/threonine kinase B 15 40161023-40221136 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008419 Supported Cytosol Tissue enhanced 0 testis: 40.2 lymph node: 15.1 -PDE6D JBTS22 ENSG00000156973 Phosphodiesterase 6D, cGMP-specific, rod, delta 2 231732425-231786272 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037433, HPA037434 Uncertain Expressed in all testis: 48.0 -EIF4A2 BM-010, DDX2B, EIF4A, EIF4F ENSG00000156976 Eukaryotic translation initiation factor 4A2 3 186783205-186789900 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011690, HPA068286 Uncertain Approved Cytosol Expressed in all ovary: 724.4 -BRPF1 BR140 ENSG00000156983 Bromodomain and PHD finger containing, 1 3 9731729-9748018 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003359 Supported Approved Plasma membrane
Cytosol Expressed in all testis: 26.3 -RPUSD3 MGC29784 ENSG00000156990 RNA pseudouridylate synthase domain containing 3 3 9837849-9844602 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037551, HPA037552 Uncertain Approved Nucleus Expressed in all testis: 54.2 -SST SMST ENSG00000157005 Somatostatin 3 187668906-187670399 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000075, HPA019472 Supported Supported Tissue enhanced 0 cerebral cortex: 212.6;duodenum: 387.3;stomach: 304.0 small intestine: 145.4 -TATDN2 KIAA0218 ENSG00000157014 TatD DNase domain containing 2 3 10248023-10281218 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036822, HPA058001 Approved Supported Nucleus
Nuclear speckles
Cytosol Expressed in all parathyroid gland: 37.6 -GHRL ghrelin, MTLRP, obestatin ENSG00000157017 Ghrelin/obestatin prepropeptide 3 10285675-10292947 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014246, CAB022731 Supported Tissue enriched 8 stomach: 154.8 duodenum: 19.5 -SEC13 D3S1231E, npp-20, SEC13L1, SEC13R ENSG00000157020 SEC13 homolog, nuclear pore and COPII coat complex component 3 10293131-10321178 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035292, HPA057943 Approved Supported Nucleoplasm
Vesicles Expressed in all cervix: 119.1 -EXOG ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGL-b ENSG00000157036 Endo/exonuclease (5'-3'), endonuclease G-like 3 38496127-38542161 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 7.4 -NTAN1 ENSG00000157045 N-terminal asparagine amidase 16 15037853-15056079 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051418 Approved Nucleoplasm
Golgi apparatus Expressed in all epididymis: 19.9 -SHCBP1L C1orf14 ENSG00000157060 SHC SH2-domain binding protein 1-like 1 182899865-182953525 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036124, HPA036125, HPA064821 Supported Tissue enriched 1004 testis: 100.4 epididymis: 0.0 -NMNAT2 C1orf15, KIAA0479, PNAT2 ENSG00000157064 Nicotinamide nucleotide adenylyltransferase 2 1 183248237-183418602 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 5 cerebral cortex: 73.8 heart muscle: 13.7 -ZFYVE9 MADHIP, PPP1R173, SARA, SMADIP ENSG00000157077 Zinc finger, FYVE domain containing 9 1 52142094-52346686 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017702, HPA065852, HPA065862 Approved Validated Vesicles
Cytosol Mixed parathyroid gland: 44.4 -ATP2B2 PMCA2 ENSG00000157087 ATPase, Ca++ transporting, plasma membrane 2 3 10324023-10708031 Enzymes, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005606 Supported Tissue enriched 7 cerebral cortex: 63.0 salivary gland: 9.2 -LYZL4 LYC4, MGC26768 ENSG00000157093 Lysozyme-like 4 3 42397078-42410600 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038806 Approved Tissue enriched 58 testis: 43.6 cerebral cortex: 0.7 -SLC6A1 GABATHG, GABATR, GAT1 ENSG00000157103 Solute carrier family 6 (neurotransmitter transporter), member 1 3 10992724-11039247 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013341, CAB022293 Supported Uncertain Mitochondria Group enriched 5 cerebral cortex: 119.7;liver: 50.3 parathyroid gland: 15.7 -SMG1 ATX, KIAA0421, LIP ENSG00000157106 SMG1 phosphatidylinositol 3-kinase-related kinase 16 18804853-18926454 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006870, HPA031623, HPA073972 Approved Supported Nucleoplasm Expressed in all skin: 50.3 -FCHO2 ENSG00000157107 FCH domain only 2 5 72955981-73090522 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037685, HPA037686, HPA077850 Supported Approved Vesicles
Centrosome
Cytosol Expressed in all thyroid gland: 39.5 -RBPMS HERMES ENSG00000157110 RNA binding protein with multiple splicing 8 30384479-30572261 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056999 Approved Supported Nucleoplasm
Cytosol Mixed seminal vesicle: 264.3 -TMEM171 PRP2 ENSG00000157111 Transmembrane protein 171 5 73120292-73131817 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042308 Approved Tissue enhanced 0 colon: 32.9;rectum: 32.7;thyroid gland: 47.0 duodenum: 27.1 -KLHL40 KBTBD5, NEM8, SRYP ENSG00000157119 Kelch-like family member 40 3 42685519-42692544 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024463, HPA052201 Supported Tissue enriched 14 skeletal muscle: 61.0 esophagus: 4.2 -C8A ENSG00000157131 Complement component 8, alpha polypeptide 1 56854806-56918221 Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 63 liver: 328.4 gallbladder: 5.2 -TIMP4 ENSG00000157150 TIMP metallopeptidase inhibitor 4 3 12153051-12159351 Plasma proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adipose tissue: 138.3 cerebral cortex: 27.6 -SYN2 SYNII, SYNIIa, SYNIIb ENSG00000157152 Synapsin II 3 12004402-12191400 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA037012 Supported Nucleoplasm Tissue enriched 28 cerebral cortex: 200.6 adipose tissue: 7.0 -NRG1 GGF, HGL, HRG, NDF, NRG1-IT2 ENSG00000157168 Neuregulin 1 8 31639386-32767959 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010964 Uncertain Approved Nucleoplasm Mixed thyroid gland: 19.9 -C1orf27 FLJ20505, odr-4, TTG1 ENSG00000157181 Chromosome 1 open reading frame 27 1 186375838-186421378 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015988, HPA031352 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all parathyroid gland: 75.0 -CPT2 CPT1, CPTASE ENSG00000157184 Carnitine palmitoyltransferase 2 1 53196429-53214197 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028201, HPA028202, HPA028214 Supported Supported Nucleoplasm
Nucleoli
Mitochondria Expressed in all liver: 42.1 -NECAP2 FLJ10420 ENSG00000157191 NECAP endocytosis associated 2 1 16440672-16460078 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028077 Approved Approved Endoplasmic reticulum Expressed in all spleen: 87.6 -LRP8 APOER2, HSZ75190, LRP-8, MCI1 ENSG00000157193 Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 1 53242364-53328070 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 7 cerebral cortex: 25.2;testis: 47.4;thyroid gland: 87.3 appendix: 7.9 -CDCP2 ENSG00000157211 CUB domain containing protein 2 1 54133074-54153770 Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level HPA031143 Uncertain Not detected cervix: 0.1 -PAXIP1 CAGF28, CAGF29, PAXIP1L, PTIP, TNRC2 ENSG00000157212 PAX interacting (with transcription-activation domain) protein 1 7 154943687-155003084 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006694, HPA016950 Supported Approved Nucleoplasm
Vesicles Mixed testis: 16.3 -STEAP2 IPCA-1, PCANAP1, STAMP1, STMP ENSG00000157214 STEAP family member 2, metalloreductase 7 90167590-90238137 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029115, HPA055603 Uncertain Supported Vesicles Tissue enriched 11 prostate: 205.1 parathyroid gland: 18.5 -SSBP3 CSDP, FLJ10355, SSDP, SSDP1 ENSG00000157216 Single stranded DNA binding protein 3 1 54225432-54413479 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 117.3 -HTR5A 5-HT5A ENSG00000157219 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 7 155070324-155085749 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB017467 Approved Tissue enriched 11 cerebral cortex: 8.6 testis: 0.7 -CLDN12 ENSG00000157224 Claudin 12 7 90383721-90513402 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026945 Approved Expressed in all prostate: 40.8 -MMP14 MT1-MMP ENSG00000157227 Matrix metallopeptidase 14 (membrane-inserted) 14 22836557-22849027 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009918, HPA051432 Approved Approved Intermediate filaments
Cytosol Mixed endometrium: 236.1 -FZD1 DKFZp564G072 ENSG00000157240 Frizzled class receptor 1 7 91264364-91271326 Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013008 Approved Supported Plasma membrane Mixed thyroid gland: 32.3 -GATAD1 FLJ22489, ODAG, RG083M05.2 ENSG00000157259 GATA zinc finger domain containing 1 7 92447453-92458836 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006105, HPA072785 Supported Nucleus Expressed in all thyroid gland: 42.5 -SUSD3 MGC26847 ENSG00000157303 Sushi domain containing 3 9 93058688-93085138 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042310 Uncertain Approved Nucleus Tissue enhanced 0 testis: 91.7 lymph node: 67.3 -TMED6 MGC23911, p24g5, p24gamma5 ENSG00000157315 Transmembrane p24 trafficking protein 6 16 69343248-69351809 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012532 Approved Tissue enhanced 0 fallopian tube: 35.5;pancreas: 61.2;stomach: 36.5 epididymis: 21.9 -CLEC18A MRCL ENSG00000157322 C-type lectin domain family 18, member A 16 69950705-69964452 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048976 Uncertain Group enriched 7 kidney: 15.6;testis: 3.7 adrenal gland: 1.3 -DHRS4 FLJ11008, humNRDR, SCAD-SRL, SDR-SRL, SDR25C2 ENSG00000157326 Dehydrogenase/reductase (SDR family) member 4 14 23953586-23969279 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023972 Uncertain Approved Nuclear membrane
Vesicles Expressed in all kidney: 149.2 -C1orf158 MGC35194 ENSG00000157330 Chromosome 1 open reading frame 158 1 12746215-12763699 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028396 Uncertain Uncertain Cytosol Group enriched 15 fallopian tube: 42.0;testis: 47.2 lung: 2.9 -CLEC18C MGC34761 ENSG00000157335 C-type lectin domain family 18, member C 16 70173322-70187361 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048976 Uncertain Group enriched 23 kidney: 12.2;testis: 3.6 duodenum: 0.3 -ARMC12 C6orf81, FLJ25390 ENSG00000157343 Armadillo repeat containing 12 6 35737032-35749079 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030895 Approved Nucleoplasm
Plasma membrane Tissue enriched 8 testis: 62.9 epididymis: 7.4 -DDX19B DBP5, DDX19 ENSG00000157349 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 16 70289663-70335283 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037229, CAB037284, HPA046380, HPA066668 Approved Uncertain Nucleoplasm Expressed in all testis: 82.7 -ST3GAL2 SIAT4B, ST3GalA.2, ST3GALII ENSG00000157350 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 16 70375978-70439237 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA017270 Approved Approved Vesicles Mixed appendix: 15.7 -FUK FLJ39408 ENSG00000157353 Fucokinase 16 70454421-70480274 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041971 Approved Approved Vesicles Expressed in all parathyroid gland: 14.2 -IL34 C16orf77, IL-34, MGC34647 ENSG00000157368 Interleukin 34 16 70579895-70660682 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 58.1;spleen: 148.3 cerebral cortex: 20.8 -DHRS1 FLJ25430, MGC20204, SDR19C1 ENSG00000157379 Dehydrogenase/reductase (SDR family) member 1 14 24290598-24299833 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000599 Approved Approved Nucleus
Centrosome
Cytosol Expressed in all esophagus: 78.6 -CACNA1D CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2 ENSG00000157388 Calcium channel, voltage-dependent, L type, alpha 1D subunit 3 53494656-53813733 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA020215 Uncertain Approved Nuclear membrane Mixed fallopian tube: 13.7 -ARSE CDPX, CDPX1 ENSG00000157399 Arylsulfatase E (chondrodysplasia punctata 1) X 2934632-2968310 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060518 Supported Golgi apparatus Tissue enhanced 0 kidney: 41.1;liver: 49.1 pancreas: 23.9 -KIT C-Kit, CD117, PBT, SCFR ENSG00000157404 V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 4 54657918-54740715 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003288, HPA004471, CAB068253, CAB072867, HPA073252 Supported Supported Plasma membrane Tissue enhanced 0 breast: 133.8 thyroid gland: 78.4 -HYDIN CILD5, DKFZp434D0513, KIAA1864, PPP1R31 ENSG00000157423 HYDIN, axonemal central pair apparatus protein 16 70807378-71230722 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067155, HPA074129 Supported Approved Plasma membrane
Cytosol Tissue enhanced 0 fallopian tube: 9.3;testis: 6.4 parathyroid gland: 5.3 -AASDH ACSF4, LYS2, NRPS998 ENSG00000157426 Aminoadipate-semialdehyde dehydrogenase 4 56338287-56387508 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036472, HPA036473 Approved Mixed parathyroid gland: 14.9 -ZNF19 KOX12, MGC51021 ENSG00000157429 Zinc finger protein 19 16 71464555-71565089 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053189, HPA063685 Uncertain Approved Mitochondria Expressed in all testis: 32.3 -CACNA2D3 HSA272268 ENSG00000157445 Calcium channel, voltage-dependent, alpha 2/delta subunit 3 3 54122547-55074557 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030849, HPA030850 Uncertain Nucleus
Cytosol Tissue enhanced 0 cerebral cortex: 16.3 adrenal gland: 5.4 -RNF111 ARK, Arkadia, DKFZP761D081, FLJ38008 ENSG00000157450 Ring finger protein 111 15 58865175-59097419 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038576, HPA038577 Approved Supported Nucleus
Cytosol Expressed in all parathyroid gland: 22.4 -CCNB2 HsT17299 ENSG00000157456 Cyclin B2 15 59105078-59125045 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008873, CAB009575 Supported Validated Golgi apparatus
Cytosol Tissue enhanced 0 testis: 122.0 bone marrow: 44.8 -FAM81A MGC26690 ENSG00000157470 Family with sequence similarity 81, member A 15 59372693-59523549 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA001847, HPA065797 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 33.4 fallopian tube: 9.8 -MYO1E HuncM-IC, MGC104638, MYO1C ENSG00000157483 Myosin IE 15 59132434-59372900 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023886 Approved Expressed in all parathyroid gland: 66.8 -APPL1 APPL ENSG00000157500 Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 3 57227737-57273468 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011138, HPA073477 Approved Uncertain Mitotic spindle
Centrosome Expressed in all parathyroid gland: 43.5 -MUM1L1 FLJ33516 ENSG00000157502 Melanoma associated antigen (mutated) 1-like 1 X 106168305-106208956 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA000168, HPA020464 Supported Tissue enriched 7 ovary: 225.9 testis: 33.8 -AFAP1L1 FLJ36748 ENSG00000157510 Actin filament associated protein 1-like 1 5 149271871-149341802 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed adipose tissue: 29.7 -TSC22D3 DIP, DSIPI, GILZ, hDIP, TSC-22R ENSG00000157514 TSC22 domain family, member 3 X 107713221-107777342 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001916 Approved Nuclear speckles
Golgi apparatus
Cytosol Expressed in all appendix: 554.1 -DSCR3 DCRA ENSG00000157538 Down syndrome critical region 3 21 37223420-37267919 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023288 Uncertain Approved Mitochondria Expressed in all kidney: 32.0 -DYRK1A DYRK, DYRK1, MNBH ENSG00000157540 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 21 37365790-37517450 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015323, HPA015810 Approved Approved Nucleoli fibrillar center
Cytosol Expressed in all parathyroid gland: 60.2 -KCNJ6 BIR1, GIRK2, hiGIRK2, KATP2, KCNJ7, Kir3.2 ENSG00000157542 Potassium channel, inwardly rectifying subfamily J, member 6 21 37607376-37916446 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 7 cerebral cortex: 2.6 epididymis: 0.3 -KCNJ15 IRKK, Kir1.3, Kir4.2 ENSG00000157551 Potassium channel, inwardly rectifying subfamily J, member 15 21 38157034-38307357 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA016702 Approved Approved Vesicles
Plasma membrane
Cytosol Tissue enhanced 0 kidney: 259.2;thyroid gland: 215.5 lung: 63.5 -ERG erg-3, p55 ENSG00000157554 V-ets avian erythroblastosis virus E26 oncogene homolog 21 38380027-38661780 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB018377, HPA046598 Approved Approved Nucleoplasm
Cytosol Expressed in all spleen: 37.3 -ETS2 ENSG00000157557 V-ets avian erythroblastosis virus E26 oncogene homolog 2 21 38805307-38824955 Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003176 Supported Nucleoplasm
Plasma membrane Expressed in all spleen: 256.3 -TSPAN18 TSPAN ENSG00000157570 Tetraspanin 18 11 44726465-44932421 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed smooth muscle: 68.4 -LCA5L C21orf13, MGC33295 ENSG00000157578 Leber congenital amaurosis 5-like 21 39405844-39445805 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA019790, HPA032010 Supported Uncertain Nucleoplasm
Cytosol Tissue enriched 16 testis: 200.6 fallopian tube: 12.3 -SLC35B2 UGTrel4 ENSG00000157593 Solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 6 44254096-44257890 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029638 Approved Approved Vesicles Expressed in all parathyroid gland: 58.0 -TMEM164 FLJ22679, RP13-360B22.2 ENSG00000157600 Transmembrane protein 164 X 110002631-110182734 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038784 Approved Approved Vesicles
Cell Junctions Expressed in all lung: 26.7 -MX1 IFI-78K, MxA ENSG00000157601 MX dynamin-like GTPase 1 21 41420304-41459214 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030917, HPA030918, HPA049724 Approved Approved Supported Nuclear membrane
Cytosol Expressed in all spleen: 120.4 -CREB3L1 OASIS ENSG00000157613 CAMP responsive element binding protein 3-like 1 11 46277661-46321422 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024069, CAB026151 Supported Uncertain Plasma membrane
Cytosol Mixed stomach: 66.1 -C2CD2 C21orf25, C21orf258, DKFZP586F0422, TMEM24L ENSG00000157617 C2 calcium-dependent domain containing 2 21 41885112-41953890 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030922, HPA030924 Approved Approved Nucleoplasm Tissue enhanced 0 adrenal gland: 110.3 spleen: 46.8 -TAB3 MAP3K7IP3 ENSG00000157625 TGF-beta activated kinase 1/MAP3K7 binding protein 3 X 30827442-30975084 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034980, HPA034981 Approved Approved Nuclear speckles
Cytosol Expressed in all parathyroid gland: 52.6 -SLC38A10 MGC15523, PP1744 ENSG00000157637 Solute carrier family 38, member 10 17 81245000-81295547 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021374, HPA023161, HPA024631 Supported Validated Golgi apparatus Expressed in all thyroid gland: 44.6 -C9orf43 MGC17358 ENSG00000157653 Chromosome 9 open reading frame 43 9 113410054-113429684 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA021310 Approved Cytosol Tissue enriched 43 testis: 73.6 parathyroid gland: 1.7 -PALM2-AKAP2 ENSG00000157654 PALM2-AKAP2 readthrough 9 109780309-110172512 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058905, HPA074153 Uncertain Uncertain Plasma membrane Tissue enhanced 0 adipose tissue: 23.3 heart muscle: 19.1 -ZNF618 KIAA1952, NEDD10 ENSG00000157657 Zinc finger protein 618 9 113876282-114056591 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023116, HPA061732 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 16.2 -DGKI DGK-IOTA ENSG00000157680 Diacylglycerol kinase, iota 7 137381037-137847092 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021924 Uncertain Approved Nucleoplasm Group enriched 10 cerebral cortex: 9.3;thyroid gland: 32.8 heart muscle: 2.0 -C9orf91 DKFZp547P234, FLJ38045 ENSG00000157693 Chromosome 9 open reading frame 91 9 114611206-114646422 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA017199 Approved Approved Plasma membrane
Cytosol Expressed in all cerebral cortex: 22.4 -SVOPL MGC46715 ENSG00000157703 SVOP-like 7 138594285-138701352 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018035 Uncertain Tissue enriched 5 parathyroid gland: 14.0 fallopian tube: 2.6 -SNX22 FLJ13952 ENSG00000157734 Sorting nexin 22 15 64151715-64157481 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038470 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 cerebral cortex: 16.4;thyroid gland: 14.7 tonsil: 9.7 -UBN2 FLJ25778, KIAA2030 ENSG00000157741 Ubinuclein 2 7 139230356-139308236 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019743, HPA020122, HPA020124 Uncertain Supported Nucleoplasm Tissue enhanced 0 testis: 27.0 skin: 11.8 -BRAF BRAF1 ENSG00000157764 B-Raf proto-oncogene, serine/threonine kinase 7 140719327-140924764 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001328, CAB004552, HPA071048 Approved Approved Vesicles
Cytosol Expressed in all testis: 41.6 -SLC34A2 NAPI-3B ENSG00000157765 Solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 4 25655301-25678748 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037989 Supported Tissue enriched 10 lung: 1127.5 fallopian tube: 111.7 -ACAN AGC1, CSPG1, CSPGCP, MSK16 ENSG00000157766 Aggrecan 15 88803443-88875354 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB016377, HPA038241, HPA038242 Supported Tissue enhanced 0 seminal vesicle: 5.0 testis: 3.3 -PSMG3 C7orf48, MGC10911, PAC3 ENSG00000157778 Proteasome (prosome, macropain) assembly chaperone 3 7 1567330-1571005 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023876 Approved Expressed in all fallopian tube: 46.9 -CABP1 ENSG00000157782 Calcium binding protein 1 12 120640552-120667324 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051438 Uncertain Tissue enriched 7 cerebral cortex: 77.6 adipose tissue: 11.2 -WDR19 DYF-2, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp ENSG00000157796 WD repeat domain 19 4 39182404-39285810 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039616, HPA058847 Uncertain Approved Nucleoplasm
Nuclear bodies Mixed fallopian tube: 30.4 -SLC37A3 DKFZp761N0624 ENSG00000157800 Solute carrier family 37, member 3 7 140293693-140404433 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA014713, HPA061841 Supported Cytosol Expressed in all endometrium: 72.5 -AP3S2 sigma3b ENSG00000157823 Adaptor-related protein complex 3, sigma 2 subunit 15 89830599-89894638 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049270 Uncertain Approved Vesicles Expressed in all parathyroid gland: 76.2 -FMNL2 FHOD2, KIAA1902 ENSG00000157827 Formin-like 2 2 152335237-152649834 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005464 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 138.2 placenta: 82.3 -GAREML FAM59B, FLJ00375, KIAA2038 ENSG00000157833 GRB2 associated, regulator of MAPK1-like 2 26173091-26189663 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA071575 Approved Cytosol Group enriched 6 cerebral cortex: 23.1;parathyroid gland: 17.5 smooth muscle: 3.4 -SPPL3 DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4 ENSG00000157837 Signal peptide peptidase like 3 12 120762510-120904371 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA004194, HPA059958 Uncertain Supported Vesicles
Plasma membrane Expressed in all parathyroid gland: 82.3 -DPYSL5 CRAM, CRMP-5, CRMP5, Ulip6 ENSG00000157851 Dihydropyrimidinase-like 5 2 26847747-26950351 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034544, HPA072387 Supported Approved Nucleoplasm
Cytosol Group enriched 8 cerebral cortex: 31.4;testis: 10.0 adrenal gland: 2.5 -DRC1 C2orf39, CCDC164, CILD21, FLJ32660, MGC16372 ENSG00000157856 Dynein regulatory complex subunit 1 2 26401916-26456711 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 10 fallopian tube: 61.8;testis: 36.7 lung: 4.8 -RAB28 ENSG00000157869 RAB28, member RAS oncogene family 4 13361354-13484365 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044575 Approved Expressed in all testis: 67.4 -FAM213B C1orf93, MGC26818 ENSG00000157870 Family with sequence similarity 213, member B 1 2586491-2591469 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA006403 Approved Approved Approved Nucleoplasm
Plasma membrane
Cytosol Mixed small intestine: 14.9 -TNFRSF14 ATAR, CD270, HVEA, HVEM, LIGHTR, TR2 ENSG00000157873 Tumor necrosis factor receptor superfamily, member 14 1 2555639-2565382 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006404, CAB026150, CAB030007 Approved Approved Cytosol
Rods & Rings Expressed in all duodenum: 46.7 -PANK4 FLJ10782 ENSG00000157881 Pantothenate kinase 4 1 2508533-2526628 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011723, HPA012036, HPA027961 Uncertain Approved Cytosol Tissue enhanced 0 appendix: 3.3 skin: 3.0 -CIB4 ENSG00000157884 Calcium and integrin binding family member 4 2 26581202-26641368 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036130, HPA036131 Uncertain Group enriched 10 testis: 19.9;thyroid gland: 4.2 placenta: 1.1 -MEGF11 DKFZp434L121, KIAA1781 ENSG00000157890 Multiple EGF-like-domains 11 15 65895079-66253747 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA017982 Uncertain Group enriched 6 cerebral cortex: 13.0;fallopian tube: 12.2 testis: 1.9 -C12orf43 FLJ12448 ENSG00000157895 Chromosome 12 open reading frame 43 12 121000486-121016502 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046148, HPA061739 Uncertain Validated Nucleoli
Golgi apparatus Expressed in all cerebral cortex: 20.7 -PEX10 RNF69 ENSG00000157911 Peroxisomal biogenesis factor 10 1 2403964-2413797 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049458, HPA049755 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 19.3 -RER1 ENSG00000157916 Retention in endoplasmic reticulum sorting receptor 1 1 2391775-2405444 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037240, HPA051400 Supported Validated Golgi apparatus Expressed in all testis: 183.8 -RADIL FLJ10324, KIAA1849, RASIP2 ENSG00000157927 Ras association and DIL domains 7 4797055-4883719 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051776 Uncertain Approved Nucleus
Nuclear membrane Tissue enhanced 0 testis: 9.5 lung: 4.3 -SKI ENSG00000157933 SKI proto-oncogene 1 2228695-2310119 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010449, HPA066567 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all endometrium: 36.1 -WIPI2 ATG18B, Atg21, CGI-50, DKFZP434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984 ENSG00000157954 WD repeat domain, phosphoinositide interacting 2 7 5190188-5233826 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019852, HPA021488 Uncertain Supported Nucleoplasm
Cytosol Expressed in all testis: 92.4 -LDLRAP1 ARH, ARH2, DKFZp586D0624, FHCB1, FHCB2, MGC34705 ENSG00000157978 Low density lipoprotein receptor adaptor protein 1 1 25543580-25568886 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003705, HPA050358 Approved Approved Microtubules Expressed in all spleen: 51.7 -AGAP1 CENTG2, GGAP1, KIAA1099 ENSG00000157985 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 2 235494089-236131800 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051405 Uncertain Expressed in all cerebral cortex: 39.6 -KRTCAP3 KCP3 ENSG00000157992 Keratinocyte associated protein 3 2 27442366-27446481 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047136, HPA060203 Supported Approved Nucleus
Cytosol Mixed small intestine: 35.5 -ANKRD61 ENSG00000157999 Ankyrin repeat domain 61 7 6031376-6036386 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA029511 Uncertain Tissue enhanced 0 testis: 11.2 bone marrow: 4.0 -PAFAH2 HSD-PLA2 ENSG00000158006 Platelet-activating factor acetylhydrolase 2, 40kDa 1 25959767-25998157 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018157 Approved Expressed in all parathyroid gland: 28.6 -EXTL1 EXTL, MGC70794 ENSG00000158008 Exostosin-like glycosyltransferase 1 1 26019884-26036464 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037749 Approved Tissue enhanced 0 cerebral cortex: 11.2 skeletal muscle: 4.3 -SLC30A2 ZNT2 ENSG00000158014 Solute carrier family 30 (zinc transporter), member 2 1 26037252-26046133 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA017979 Approved Vesicles Tissue enhanced 0 kidney: 21.9;thyroid gland: 42.3 pancreas: 16.5 -BRE BRCC4, BRCC45 ENSG00000158019 Brain and reproductive organ-expressed (TNFRSF1A modulator) 2 27889941-28338901 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017926 Approved Supported Cytosol Expressed in all adrenal gland: 190.4 -TRIM63 IRF, MURF-1, RNF28, SMRZ ENSG00000158022 Tripartite motif containing 63, E3 ubiquitin protein ligase 1 26051304-26068436 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 16 heart muscle: 100.6;skeletal muscle: 139.4 esophagus: 7.6 -WDR66 CaM-IP4, MGC33630 ENSG00000158023 WD repeat domain 66 12 121917862-122003927 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039902, HPA040005 Supported Uncertain Plasma membrane
Cytosol Tissue enhanced 0 fallopian tube: 32.2;testis: 30.6 thyroid gland: 7.4 -MRPL17 MRP-L26, RPML26 ENSG00000158042 Mitochondrial ribosomal protein L17 11 6680782-6683401 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043666, HPA050552 Uncertain Expressed in all thyroid gland: 36.9 -DUSP2 PAC-1 ENSG00000158050 Dual specificity phosphatase 2 2 96143166-96145440 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA071920 Supported Nucleus
Nuclear membrane Tissue enhanced 0 bone marrow: 79.1;seminal vesicle: 85.3 lymph node: 51.5 -GRHL3 SOM, TFCP2L4 ENSG00000158055 Grainyhead-like transcription factor 3 1 24319322-24364482 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA059960 Approved Nucleoplasm Group enriched 10 esophagus: 85.4;skin: 50.1;tonsil: 23.6;urinary bladder: 29.2 testis: 4.5 -UBXN11 SOC, SOCI, UBXD5 ENSG00000158062 UBX domain protein 11 1 26281328-26318363 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028600, HPA031357 Approved Approved Nucleoli
Cytosol Expressed in all fallopian tube: 49.6 -NLRP14 CLR11.2, GC-LRR, Nalp-iota, NALP14, NOD5, PAN8 ENSG00000158077 NLR family, pyrin domain containing 14 11 7020446-7071308 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039477 Uncertain Uncertain Cytosol Tissue enhanced 0 testis: 1.6 parathyroid gland: 0.6 -PTPDC1 FLJ37312, PTP9Q22 ENSG00000158079 Protein tyrosine phosphatase domain containing 1 9 94030794-94109856 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA016747, HPA026832 Uncertain Supported Nucleoplasm Mixed testis: 14.2 -GALNT14 FLJ12691, GalNac-T10, GalNac-T14 ENSG00000158089 Polypeptide N-acetylgalactosaminyltransferase 14 2 30910467-31155202 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA030138 Approved Nucleus
Golgi apparatus Tissue enhanced 0 kidney: 40.0 parathyroid gland: 12.5 -NCK1 NCK, NCKalpha ENSG00000158092 NCK adaptor protein 1 3 136862208-136949823 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005063, HPA030766 Supported Validated Plasma membrane
Cytosol Expressed in all lymph node: 49.5 -HPD 4-HPPD, 4HPPD, GLOD3, PPD ENSG00000158104 4-hydroxyphenylpyruvate dioxygenase 12 121839527-121863596 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038321, HPA038322 Supported Uncertain Nuclear speckles Group enriched 85 kidney: 526.3;liver: 1290.5 testis: 10.6 -RHPN1 KIAA1929, ODF5, RHPN ENSG00000158106 Rhophilin, Rho GTPase binding protein 1 8 143368855-143384220 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024288, HPA024671 Approved Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 7.3 parathyroid gland: 4.8 -TPRG1L FAM79A, FLJ21811, RP11-46F15.3 ENSG00000158109 Tumor protein p63 regulated 1-like 1 3625002-3630127 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063163 Approved Vesicles
Cytosol Expressed in all cerebral cortex: 102.5 -LRRC43 MGC35140 ENSG00000158113 Leucine rich repeat containing 43 12 122167738-122203471 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039425, HPA047606 Uncertain Approved Golgi apparatus
Vesicles Group enriched 5 fallopian tube: 29.9;testis: 8.5 parathyroid gland: 3.5 -AAED1 C9orf21 ENSG00000158122 AhpC/TSA antioxidant enzyme domain containing 1 9 96639577-96655303 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021294 Approved Expressed in all smooth muscle: 15.9 -XDH XO, XOR ENSG00000158125 Xanthine dehydrogenase 2 31334321-31414715 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062641, HPA069323 Supported Supported Nucleus Tissue enhanced 0 breast: 48.6;duodenum: 46.9;liver: 35.9;small intestine: 55.8 colon: 11.4 -XKR8 FLJ10307 ENSG00000158156 XK, Kell blood group complex subunit-related family, member 8 1 27959462-27968096 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA049984, HPA053529 Uncertain Approved Golgi apparatus Expressed in all placenta: 13.6 -CNNM4 ACDP4, KIAA1592 ENSG00000158158 Cyclin and CBS domain divalent metal cation transport mediator 4 2 96760902-96811891 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017732 Supported Uncertain Plasma membrane
Actin filaments Expressed in all rectum: 37.5 -EYA3 DKFZp686C132 ENSG00000158161 EYA transcriptional coactivator and phosphatase 3 1 27970344-28088696 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052432, HPA062889 Uncertain Validated Nucleoplasm Expressed in all testis: 20.8 -DZIP1L DZIP2, FLJ32844 ENSG00000158163 DAZ interacting zinc finger protein 1-like 3 138061990-138115818 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030404 Approved Approved Nucleoplasm
Microtubules
Cytokinetic bridge Mixed fallopian tube: 16.5 -TMSB15A TMSL8, TMSNB ENSG00000158164 Thymosin beta 15a X 102513676-102516784 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 prostate: 26.7 thyroid gland: 8.5 -FANCC FA3, FAC, FACC ENSG00000158169 Fanconi anemia, complementation group C 9 95099054-95317709 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017793, HPA030771 Approved Supported Nucleoplasm Mixed testis: 18.1 -MRAS M-RAs, R-RAS3, RRAS3 ENSG00000158186 Muscle RAS oncogene homolog 3 138347648-138405534 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042728 Approved Approved Vesicles Expressed in all cerebral cortex: 114.4 -WASF2 SCAR2, WAVE2 ENSG00000158195 WAS protein family, member 2 1 27404226-27490158 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022632, HPA045288 Supported Approved Plasma membrane
Cytosol Expressed in all esophagus: 88.5 -ABHD3 LABH3 ENSG00000158201 Abhydrolase domain containing 3 18 21650897-21704805 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010729 Approved Approved Nucleus
Vesicles
Plasma membrane Expressed in all rectum: 72.4 -ESYT3 CHR3SYT, FAM62C ENSG00000158220 Extended synaptotagmin-like protein 3 3 138434586-138481686 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039200 Approved Tissue enhanced 0 lung: 8.4;skin: 7.5;thyroid gland: 8.4 endometrium: 3.6 -FAIM FAIM1, FLJ10582 ENSG00000158234 Fas apoptotic inhibitory molecule 3 138608606-138633376 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042440, HPA052209 Approved Approved Plasma membrane
Cytosol Expressed in all fallopian tube: 60.5 -FAM46B MGC16491 ENSG00000158246 Family with sequence similarity 46, member B 1 27005020-27012836 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 esophagus: 60.1;skin: 39.5 seminal vesicle: 21.8 -CLSTN2 CDHR13, CS2, CSTN2, FLJ39113 ENSG00000158258 Calsyntenin 2 3 139935185-140577397 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031342, HPA061800 Approved Approved Vesicles Tissue enhanced 0 cerebral cortex: 35.3;ovary: 95.1 adipose tissue: 19.8 -COLEC12 CL-P1, SCARA4, SRCL ENSG00000158270 Collectin sub-family member 12 18 316740-500722 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047917, HPA071056 Supported Approved Golgi apparatus
Vesicles
Cell Junctions Tissue enhanced 0 placenta: 28.2 lung: 16.7 -RNF207 C1orf188, FLJ32096, FLJ46380 ENSG00000158286 Ring finger protein 207 1 6205475-6221299 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028378, HPA042535 Uncertain Approved Cytosol Tissue enhanced 0 heart muscle: 10.4 seminal vesicle: 5.3 -CUL4B ENSG00000158290 Cullin 4B X 120524609-120575794 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003046, HPA011880, CAB017786, HPA058979 Supported Validated Nucleoplasm Expressed in all testis: 68.0 -GPR153 PGR1 ENSG00000158292 G protein-coupled receptor 153 1 6247346-6260975 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA007159 Approved Mixed cervix: 17.3 -SLC13A3 NADC3, SDCT2 ENSG00000158296 Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 20 46557823-46684467 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014353, HPA014736 Supported Tissue enriched 7 kidney: 428.6 placenta: 60.6 -GPRASP2 FLJ37327, GASP2 ENSG00000158301 G protein-coupled receptor associated sorting protein 2 X 102712176-102717733 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017438 Approved Approved Nucleoplasm
Cytosol Mixed cerebral cortex: 41.7 -RHBDL2 FLJ20435 ENSG00000158315 Rhomboid, veinlet-like 2 (Drosophila) 1 38885807-38941799 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043807 Approved Mixed rectum: 22.5 -AUTS2 FBRSL2, KIAA0442 ENSG00000158321 Autism susceptibility candidate 2 7 69598919-70793068 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000390 Approved Approved Nucleoplasm
Cytosol Expressed in all skin: 21.7 -SHROOM4 KIAA1202 ENSG00000158352 Shroom family member 4 X 50591647-50814302 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010565 Uncertain Tissue enhanced 0 lung: 19.3 placenta: 13.0 -HIST1H2BD H2B/b, H2BFB ENSG00000158373 Histone cluster 1, H2bd 6 26158146-26171349 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671, CAB062336 Supported Approved Nucleoplasm
Cytosol Expressed in all prostate: 84.8 -CDC25C CDC25, PPP1R60 ENSG00000158402 Cell division cycle 25C 5 138285265-138338355 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003800, HPA066991 Uncertain Supported Nuclear speckles Tissue enriched 7 testis: 31.7 rectum: 4.4 -HIST1H4H H4/h, H4FH ENSG00000158406 Histone cluster 1, H4h 6 26277609-26285638 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Tissue enhanced 0 breast: 9.7 prostate: 6.5 -MITD1 LOC129531 ENSG00000158411 MIT, microtubule interacting and transport, domain containing 1 2 99161427-99181058 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036162, HPA036163 Approved Validated Vesicles Expressed in all lymph node: 44.8 -EIF5B DKFZp434I036, FLJ10524, IF2, KIAA0741 ENSG00000158417 Eukaryotic translation initiation factor 5B 2 99337353-99401326 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034648, HPA040095 Approved Approved Plasma membrane
Cytosol Expressed in all testis: 67.2 -RIBC1 FLJ32783 ENSG00000158423 RIB43A domain with coiled-coils 1 X 53422690-53431120 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001150, HPA021613 Uncertain Approved Nuclear bodies Group enriched 7 fallopian tube: 44.6;testis: 41.6 thyroid gland: 6.1 -TMSB15B MGC39900 ENSG00000158427 Thymosin beta 15B X 103918896-103966712 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA064607 Uncertain Mixed endometrium: 18.6 -CATIP C2orf62, MGC50811 ENSG00000158428 Ciliogenesis associated TTC17 interacting protein 2 218356856-218368099 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044818 Supported Tissue enhanced 0 fallopian tube: 31.6 testis: 7.2 -CNOT11 C2orf29, C40 ENSG00000158435 CCR4-NOT transcription complex, subunit 11 2 101252802-101270316 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069823 Supported Nucleoplasm Expressed in all testis: 51.8 -KCNB1 Kv2.1 ENSG00000158445 Potassium channel, voltage gated Shab related subfamily B, member 1 20 49363877-49484297 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001979, HPA042434 Supported Tissue enhanced 0 adipose tissue: 11.0;cerebral cortex: 21.0 fallopian tube: 7.5 -TSPAN33 MGC50844, Penumbra ENSG00000158457 Tetraspanin 33 7 129144892-129169697 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA020357 Approved Approved Microtubules Expressed in all kidney: 126.4 -NRG2 Don-1, HRG2, NTAK ENSG00000158458 Neuregulin 2 5 139846779-140043299 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038935, HPA047973 Uncertain Supported Nucleus
Nucleoli Tissue enhanced 0 parathyroid gland: 13.1 ovary: 10.2 -AHCYL2 KIAA0828 ENSG00000158467 Adenosylhomocysteinase-like 2 7 129225023-129430211 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053128 Uncertain Approved Nucleoplasm
Cytosol Expressed in all rectum: 198.1 -B4GALT5 beta4GalT-V ENSG00000158470 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 20 49632945-49713878 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Expressed in all bone marrow: 59.9 -CD1D ENSG00000158473 CD1d molecule 1 158179947-158184896 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016107, HPA072662 Uncertain Supported Endoplasmic reticulum Mixed spleen: 20.9 -CD1A CD1 ENSG00000158477 CD1a molecule 1 158254137-158258269 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB000009, HPA010734 Supported Group enriched 6 esophagus: 9.5;skin: 27.1 tonsil: 3.1 -SPATA2 KIAA0757, PD1, PPP1R145, tamo ENSG00000158480 Spermatogenesis associated 2 20 49903391-49915508 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048581, HPA052224 Uncertain Approved Nucleus
Nucleoli fibrillar center Expressed in all cerebral cortex: 22.4 -CD1C CD1 ENSG00000158481 CD1c molecule 1 158289786-158293630 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 spleen: 41.2;tonsil: 47.1 lymph node: 40.3 -FAM86C1 FAM86C, FLJ10661, FLJ27199 ENSG00000158483 Family with sequence similarity 86, member C1 11 71787510-71801236 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed thyroid gland: 9.8 -CD1B CD1 ENSG00000158485 CD1b molecule 1 158327951-158331531 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021824 Approved Tissue enhanced 0 rectum: 3.2;skin: 3.9 lymph node: 2.8 -DNAH3 DKFZp434N074, DLP3, Dnahc3b, Hsadhc3 ENSG00000158486 Dynein, axonemal, heavy chain 3 16 20933111-21159441 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062493 Approved Nuclear membrane
Intermediate filaments Group enriched 5 fallopian tube: 8.0;testis: 5.9 lung: 1.3 -CD1E ENSG00000158488 CD1e molecule 1 158353696-158357553 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057769 Uncertain Tissue enhanced 0 skin: 18.3 tonsil: 10.8 -HMHB1 HB-1, HB-1Y ENSG00000158497 Histocompatibility (minor) HB-1 5 143812161-143820719 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 1.8 lymph node: 0.7 -CPA2 ENSG00000158516 Carboxypeptidase A2 (pancreatic) 7 130266827-130289798 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020342, HPA021317 Supported Tissue enriched 107 pancreas: 9279.4 stomach: 86.6 -NCF1 NCF1A, NOXO2, p47phox, SH3PXD1A ENSG00000158517 Neutrophil cytosolic factor 1 7 74773962-74789315 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004524, HPA047836, HPA052095 Supported Tissue enhanced 0 lymph node: 72.1;spleen: 75.3 bone marrow: 61.0 -CPA5 ENSG00000158525 Carboxypeptidase A5 7 130344816-130368730 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA020322 Approved Nucleus Tissue enriched 11 testis: 47.1 spleen: 4.2 -TSR2 DT1P1A10, RP1-112K5.2, WGG1 ENSG00000158526 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) X 54440401-54445487 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030514 Approved Approved Nucleus
Nucleoli
Cell Junctions
Cytosol Expressed in all cerebral cortex: 88.7 -PPP1R9A FLJ20068, KIAA1222, Neurabin-I ENSG00000158528 Protein phosphatase 1, regulatory subunit 9A 7 94907202-95296415 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027726 Uncertain Approved Nucleoplasm
Cytosol Mixed cerebral cortex: 20.6 -ZC3H18 NHN1 ENSG00000158545 Zinc finger CCCH-type containing 18 16 88570381-88631966 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040847, HPA041327 Supported Validated Nuclear speckles Expressed in all testis: 30.8 -ZFAND2B AIRAPL ENSG00000158552 Zinc finger, AN1-type domain 2B 2 219195237-219209651 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035159, HPA035160 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all thyroid gland: 68.1 -POM121L2 POM121-L ENSG00000158553 POM121 transmembrane nucleoporin-like 2 6 27285903-27312170 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA046150 Uncertain Tissue enriched 152 testis: 15.2 epididymis: 0.0 -GDPD5 GDE2, PP1665 ENSG00000158555 Glycerophosphodiester phosphodiesterase domain containing 5 11 75434640-75525903 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065257, HPA066762, HPA069281 Uncertain Approved Golgi apparatus Tissue enhanced 0 spleen: 68.0 testis: 31.2 -DYNC1I1 DNCI1, DNCIC1 ENSG00000158560 Dynein, cytoplasmic 1, intermediate chain 1 7 95772506-96110322 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061689 Supported Tissue enhanced 0 cerebral cortex: 84.2 adrenal gland: 16.9 -PFKFB1 PFRX ENSG00000158571 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 X 54932961-54998534 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 8 adipose tissue: 30.0;liver: 18.9;skeletal muscle: 39.3 breast: 3.8 -ALAS2 ASB ENSG00000158578 5'-aminolevulinate synthase 2 X 55009055-55031064 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001638 Approved Tissue enriched 7 bone marrow: 336.2 placenta: 50.5 -TMED4 HNLF, p24a3, p24alpha3 ENSG00000158604 Transmembrane p24 trafficking protein 4 7 44577894-44582287 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014650 Approved Expressed in all thyroid gland: 190.1 -PPP1R15B FLJ14744 ENSG00000158615 Protein phosphatase 1, regulatory subunit 15B 1 204403387-204411791 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061088 Approved Golgi apparatus Expressed in all bone marrow: 81.7 -COPG2 2-COP ENSG00000158623 Coatomer protein complex, subunit gamma 2 7 130506238-130668748 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045712 Approved Expressed in all ovary: 48.0 -C11orf30 EMSY ENSG00000158636 Chromosome 11 open reading frame 30 11 76444923-76553025 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012234, HPA050777 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 20.0 -PAGE5 CT16.1, CT16.2, PAGE-5 ENSG00000158639 P antigen family, member 5 (prostate associated) X 55220355-55224108 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052619, HPA055869 Supported Uncertain Mitochondria Tissue enriched 74 testis: 40.6 fallopian tube: 0.5 -GPAT4 AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7 ENSG00000158669 Glycerol-3-phosphate acyltransferase 4 8 41577187-41625001 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016471 Approved Expressed in all parathyroid gland: 78.7 -PKD1L1 PRO19563 ENSG00000158683 Polycystic kidney disease 1 like 1 7 47774652-47948491 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020422, HPA022424 Uncertain Tissue enhanced 0 testis: 2.4 adipose tissue: 1.8 -ZSCAN12 dJ29K1.2, KIAA0426, ZFP96, ZNF29K1, ZNF305, ZNF96 ENSG00000158691 Zinc finger and SCAN domain containing 12 6 28378955-28399734 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA006637 Approved Approved Microtubules
Cytosol Mixed thyroid gland: 8.6 -TAGLN2 HA1756, KIAA0120 ENSG00000158710 Transgelin 2 1 159918107-159925732 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001925 Approved Approved Actin filaments
Cytosol Expressed in all lung: 904.3 -ELK4 SAP1 ENSG00000158711 ELK4, ETS-domain protein (SRF accessory protein 1) 1 205597556-205631962 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028863 Uncertain Supported Nucleoplasm Expressed in all prostate: 41.5 -SLAMF8 BLAME, CD353, SBBI42 ENSG00000158714 SLAM family member 8 1 159826750-159837249 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067601 Supported Tissue enhanced 0 appendix: 40.5 lymph node: 36.7 -SLC45A3 IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein ENSG00000158715 Solute carrier family 45, member 3 1 205657851-205680459 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019073, HPA019075 Supported Approved Nucleoplasm
Vesicles Tissue enriched 25 prostate: 430.6 stomach: 16.9 -DUSP23 DUSP25, FLJ20442 ENSG00000158716 Dual specificity phosphatase 23 1 159780932-159782543 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028211, HPA045792 Approved Supported Nucleoplasm Expressed in all adrenal gland: 40.6 -RNF166 MGC14381, MGC2647 ENSG00000158717 Ring finger protein 166 16 88696495-88706421 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042970 Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all bone marrow: 57.2 -NBL1 D1S1733E, DAN, DAND1, NB, NO3 ENSG00000158747 Neuroblastoma 1, DAN family BMP antagonist 1 19640554-19658456 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007394, CAB026132 Uncertain Expressed in all ovary: 551.6 -HTR6 5-HT6, 5-HT6R ENSG00000158748 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1 19665287-19679562 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Not detected cerebral cortex: 0.8 -ITLN2 HL-2 ENSG00000158764 Intelectin 2 1 160945025-160954799 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA006683 Approved Group enriched 20 duodenum: 251.5;small intestine: 463.3 lung: 18.3 -F11R CD321, JAM-1, JAM-A, JAM1, JAMA, JCAM, PAM-1 ENSG00000158769 F11 receptor 1 160995211-161021348 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004671, HPA043616, HPA061700 Supported Approved Cell Junctions
Microtubules Expressed in all lung: 95.1 -USF1 bHLHb11, MLTFI, UEF ENSG00000158773 Upstream transcription factor 1 1 161039251-161045977 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001480, HPA036233, HPA036535 Supported Validated Nucleoplasm Expressed in all spleen: 35.5 -PLA2G2F ENSG00000158786 Phospholipase A2, group IIF 1 20139326-20150386 Enzymes, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 11 skin: 11.4;tonsil: 7.5;urinary bladder: 4.0 gallbladder: 0.6 -SPATA2L C16orf76, MGC26885, tamo ENSG00000158792 Spermatogenesis associated 2-like 16 89696343-89701705 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041182, HPA042453 Uncertain Approved Nucleoplasm
Mitochondria
Cytosol Mixed cerebral cortex: 9.2 -NIT1 ENSG00000158793 Nitrilase 1 1 161118086-161125445 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006657 Approved Expressed in all parathyroid gland: 48.7 -DEDD CASP8IP1, DEDD1, DEFT, FLDED1, KE05 ENSG00000158796 Death effector domain containing 1 161120974-161132688 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA030681 Uncertain Nucleus Expressed in all testis: 47.4 -ZNF276 CENP-Z, CENPZ, MGC45417, ZADT, ZFP276, ZNF477 ENSG00000158805 Zinc finger protein 276 16 89720400-89740903 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021309, HPA022255 Uncertain Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Expressed in all spleen: 23.2 -NPM2 ENSG00000158806 Nucleophosmin/nucleoplasmin 2 8 22024125-22036897 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041070 Supported Approved Nucleus
Nucleoli Tissue enhanced 0 parathyroid gland: 68.6;thyroid gland: 42.7 cerebral cortex: 31.9 -EDA ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED ENSG00000158813 Ectodysplasin A X 69616067-70039469 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA037972, HPA037973 Supported Vesicles
Lipid droplets Tissue enhanced 0 parathyroid gland: 19.0 thyroid gland: 10.0 -FGF17 FGF-13 ENSG00000158815 Fibroblast growth factor 17 8 22042398-22048809 Cancer-related genes, Disease related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052600 Approved Mixed adrenal gland: 1.8 -VWA5B1 FLJ32784 ENSG00000158816 Von Willebrand factor A domain containing 5B1 1 20290919-20354894 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027496, HPA028405, HPA064829 Supported Approved Plasma membrane
Mitochondria
Cytosol Group enriched 5 epididymis: 7.9;testis: 5.0 parathyroid gland: 1.2 -CDA CDD ENSG00000158825 Cytidine deaminase 1 20588948-20618908 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064202 Approved Approved Nucleoplasm Tissue enhanced 0 bone marrow: 104.8;esophagus: 56.9 liver: 33.1 -PINK1 PARK6 ENSG00000158828 PTEN induced putative kinase 1 1 20633455-20651511 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA001931, CAB026191 Uncertain Expressed in all cerebral cortex: 145.9 -B4GALT3 beta4Gal-T3 ENSG00000158850 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 1 161171310-161177968 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010793 Approved Supported Golgi apparatus Expressed in all placenta: 31.0 -DMTN DMT, EPB49 ENSG00000158856 Dematin actin binding protein 8 22048995-22082527 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024290 Uncertain Expressed in all cerebral cortex: 222.1 -ADAMTS4 ADAMTS-2, ADMP-1, KIAA0688 ENSG00000158859 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1 161184308-161199056 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025876, HPA051296, HPA068374 Uncertain Approved Nuclear speckles Tissue enhanced 0 adipose tissue: 62.7 appendix: 23.4 -FAM160B2 FLJ21801, RAI16 ENSG00000158863 Family with sequence similarity 160, member B2 8 22089159-22104898 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA025040 Approved Approved Nucleoplasm
Cytosol Expressed in all seminal vesicle: 18.4 -NDUFS2 CI-49 ENSG00000158864 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1 161197104-161214395 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055140, HPA061953 Supported Validated Nucleoplasm
Mitochondria Expressed in all heart muscle: 126.4 -SLC5A11 KST1, SGLT6, SMIT2 ENSG00000158865 Solute carrier family 5 (sodium/inositol cotransporter), member 11 16 24845841-24911628 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035331 Uncertain Approved Nucleus
Cytosol Group enriched 6 cerebral cortex: 10.5;duodenum: 6.8;kidney: 6.0;small intestine: 15.5 breast: 1.7 -FCER1G ENSG00000158869 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1 161215234-161220699 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022108, HPA026872 Supported Expressed in all spleen: 470.3 -APOA2 ENSG00000158874 Apolipoprotein A-II 1 161222292-161223631 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025885 Supported Tissue enriched 1053 liver: 18141.3 bone marrow: 17.2 -TOMM40L FLJ12770, TOMM40B ENSG00000158882 Translocase of outer mitochondrial membrane 40 homolog (yeast)-like 1 161225939-161230744 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051304 Approved Mixed parathyroid gland: 19.9 -MPZ CMT1, CMT1B, CMT2I, CMT2J, HMSNIB ENSG00000158887 Myelin protein zero 1 161304735-161309972 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed seminal vesicle: 16.5 -WFDC8 C20orf170, dJ461P17.1, WAP8 ENSG00000158901 WAP four-disulfide core domain 8 20 45551153-45579326 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 409 epididymis: 479.0 seminal vesicle: 1.1 -CCAR2 DBC-1, DBC1, KIAA1967, NET35 ENSG00000158941 Cell cycle and apoptosis regulator 2 8 22604632-22621514 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019907, HPA019943, CAB072827, CAB072828 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all testis: 136.6 -WNT9B WNT14B, WNT15 ENSG00000158955 Wingless-type MMTV integration site family, member 9B 17 46833201-46886730 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058361, HPA059572 Approved Tissue enhanced 0 epididymis: 5.7;seminal vesicle: 9.3 parathyroid gland: 3.1 -CACHD1 KIAA1573, VWCD1 ENSG00000158966 Cache domain containing 1 1 64470792-64693058 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA017202 Uncertain Uncertain Nucleus
Nucleoli Mixed ovary: 28.0 -CDC42SE2 FLJ21967, SPEC2 ENSG00000158985 CDC42 small effector 2 5 131245493-131398447 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038624 Supported Expressed in all lymph node: 94.1 -RAPGEF6 PDZ-GEF2, PDZGEF2, RA-GEF-2 ENSG00000158987 Rap guanine nucleotide exchange factor (GEF) 6 5 131423921-131635236 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037982, HPA037983 Approved Approved Centrosome
Cytosol Mixed lymph node: 22.1 -EPB41 4.1R, EL1 ENSG00000159023 Erythrocyte membrane protein band 4.1 1 28887091-29120046 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028076, HPA028412, HPA028414 Supported Supported Plasma membrane
Cell Junctions
Cytosol Expressed in all lymph node: 51.3 -MIS18A B28, C21orf45, C21orf46, FASP1, hMis18alpha ENSG00000159055 MIS18 kinetochore protein A 21 32268219-32279069 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018286, HPA020585 Approved Approved Nucleus
Cytosol Mixed testis: 38.6 -ALG8 MGC2840 ENSG00000159063 ALG8, alpha-1,3-glucosyltransferase 11 78100936-78139660 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051898 Approved Approved Nucleoplasm Expressed in all testis: 85.6 -FBXW5 DKFZP434B205, Fbw5, MGC20962 ENSG00000159069 F-box and WD repeat domain containing 5 9 136940435-136944696 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046615 Approved Approved Mitochondria Expressed in all testis: 163.4 -C21orf59 C21orf48, CILD26, FBB18, FLJ20467 ENSG00000159079 Chromosome 21 open reading frame 59 21 32592079-32612866 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018453, HPA019055, HPA028849, CAB034170 Supported Supported Approved Rods & Rings Expressed in all testis: 78.2 -SYNJ1 INPP5G, PARK20 ENSG00000159082 Synaptojanin 1 21 32628759-32728048 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011916 Supported Approved Nucleoplasm
Centrosome
Cytosol Tissue enhanced 0 cerebral cortex: 66.1 testis: 18.3 -PAXBP1 C21orf66, fSAP105, GCFC, GCFC1 ENSG00000159086 PAX3 and PAX7 binding protein 1 21 32733899-32771858 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003757 Approved Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 18.7 -IFNAR2 IFNABR ENSG00000159110 Interferon (alpha, beta and omega) receptor 2 21 33229901-33265675 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025889 Approved Expressed in all spleen: 59.7 -MRPL10 L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8 ENSG00000159111 Mitochondrial ribosomal protein L10 17 47823272-47831534 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021234, HPA029885 Supported Validated Mitochondria Expressed in all ovary: 61.0 -IFNGR2 AF-1, IFNGT1 ENSG00000159128 Interferon gamma receptor 2 (interferon gamma transducer 1) 21 33402896-33479348 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA001535 Approved Approved Nucleoplasm
Golgi apparatus Mixed spleen: 10.3 -GART PGFT, PRGS ENSG00000159131 Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 21 33503931-33543491 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002119, HPA005779 Approved Uncertain Nucleoplasm
Mitochondria
Cytosol Expressed in all testis: 55.3 -SON BASS1, C21orf50, DBP-5, FLJ21099, FLJ33914, KIAA1019, NREBP ENSG00000159140 SON DNA binding protein 21 33542618-33577481 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023535, HPA031755, HPA031756 Supported Validated Nuclear speckles Expressed in all parathyroid gland: 220.0 -DONSON B17, C21orf60, C2TA, DKFZP434M035 ENSG00000159147 Downstream neighbor of SON 21 33559542-33588708 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039558, HPA049033 Uncertain Approved Nucleoplasm
Cell Junctions
Cytosol Tissue enhanced 0 testis: 40.2 parathyroid gland: 15.4 -SV2A KIAA0736, SV2 ENSG00000159164 Synaptic vesicle glycoprotein 2A 1 149903318-149917882 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002226, HPA007863 Supported Approved Cytosol Tissue enhanced 0 cerebral cortex: 167.4;parathyroid gland: 70.8 epididymis: 27.9 -LAD1 ENSG00000159166 Ladinin 1 1 201373244-201399915 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007256, HPA028732 Approved Approved Actin filaments Tissue enhanced 0 esophagus: 293.1;skin: 236.9 small intestine: 96.0 -STC1 STC ENSG00000159167 Stanniocalcin 1 8 23841915-23854807 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018625, HPA023918 Approved Tissue enhanced 0 cervix, uterine: 77.7 endometrium: 53.9 -TNNI1 ENSG00000159173 Troponin I type 1 (skeletal, slow) 1 201403768-201429866 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028190 Approved Uncertain Nucleus
Nucleoli Tissue enriched 21 skeletal muscle: 4421.8 esophagus: 207.3 -CSRP1 CSRP, CYRP, D1S181E ENSG00000159176 Cysteine and glycine-rich protein 1 1 201483530-201509456 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045617 Uncertain Expressed in all seminal vesicle: 3274.8 -PRAC1 C17orf92, PRAC ENSG00000159182 Prostate cancer susceptibility candidate 1 17 48721719-48722522 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047871 Approved Group enriched 38 colon: 105.4;prostate: 197.0;rectum: 224.2 urinary bladder: 4.5 -HOXB13 ENSG00000159184 Homeobox B13 17 48724763-48729178 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004438, HPA062852, HPA065019 Supported Validated Nucleoplasm Tissue enhanced 0 prostate: 112.2;rectum: 39.9 colon: 21.9 -C1QC C1QG ENSG00000159189 Complement component 1, q subcomponent, C chain 1 22643630-22648110 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001471, CAB009828 Supported Uncertain Vesicles Expressed in all spleen: 1310.5 -KCNE2 LQT6, MiRP1 ENSG00000159197 Potassium channel, voltage gated subfamily E regulatory beta subunit 2 21 34364024-34371389 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029706, HPA051553 Supported Tissue enriched 23 stomach: 170.2 testis: 7.3 -ATP5G1 ATP5G ENSG00000159199 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 17 48892765-48895871 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all heart muscle: 406.5 -RCAN1 DSCR1 ENSG00000159200 Regulator of calcineurin 1 21 34513142-34615142 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB037218 Uncertain Approved Cytosol Tissue enriched 8 parathyroid gland: 1096.4 placenta: 136.4 -UBE2Z FLJ13855, USE1 ENSG00000159202 Ubiquitin-conjugating enzyme E2Z 17 48908369-48929056 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007922 Approved Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 82.4 -CIART BC017397, C1orf51 ENSG00000159208 Circadian associated repressor of transcription 1 150282543-150287093 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027515, HPA054349 Approved Supported Nucleoplasm Mixed seminal vesicle: 33.5 -SNF8 Dot3, EAP30, VPS22 ENSG00000159210 SNF8, ESCRT-II complex subunit 17 48929316-48945117 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059320 Approved Supported Nucleoplasm
Cytosol Expressed in all epididymis: 42.7 -CLIC6 CLIC1L, CLIC5 ENSG00000159212 Chloride intracellular channel 6 21 34669389-34718227 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055123, HPA065285 Approved Tissue enhanced 0 stomach: 76.8 cervix: 24.3 -CCDC24 MGC45441 ENSG00000159214 Coiled-coil domain containing 24 1 43991359-43996528 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035424, HPA061710 Uncertain Validated Plasma membrane
Cytosol Tissue enhanced 0 fallopian tube: 18.1 testis: 15.2 -RUNX1 AML1, AMLCR1, CBFA2, PEBP2A2 ENSG00000159216 Runt-related transcription factor 1 21 34787801-36004667 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004176, HPA037912 Supported Validated Nucleoplasm
Vesicles Mixed breast: 33.8 -IGF2BP1 IMP-1 ENSG00000159217 Insulin-like growth factor 2 mRNA binding protein 1 17 48997412-49055650 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021367, HPA062273 Supported Supported Cytosol Group enriched 6 placenta: 7.9;testis: 9.0 kidney: 1.4 -GIP ENSG00000159224 Gastric inhibitory polypeptide 17 48958554-48968596 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016729, HPA021612 Supported Group enriched 155 duodenum: 268.7;small intestine: 96.7 stomach: 1.1 -CBR1 CBR, SDR21C1 ENSG00000159228 Carbonyl reductase 1 21 36069941-36073166 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018433 Approved Approved Nucleus
Cytosol Expressed in all duodenum: 560.1 -CBR3 SDR21C2 ENSG00000159231 Carbonyl reductase 3 21 36134912-36146566 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018434 Uncertain Supported Nucleoplasm
Cytosol Mixed skin: 20.7 -C2orf81 hCG40743, LOC388963 ENSG00000159239 Chromosome 2 open reading frame 81 2 74414176-74421591 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA054835 Approved Approved Nucleus
Nucleoli Tissue enhanced 0 fallopian tube: 31.9;testis: 26.6 parathyroid gland: 9.8 -GJD2 CX36, GJA9 ENSG00000159248 Gap junction protein, delta 2, 36kDa 15 34751032-34754965 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014355 Uncertain Group enriched 6 adrenal gland: 8.0;cerebral cortex: 1.9 pancreas: 0.8 -ACTC1 ACTC, CMD1R ENSG00000159251 Actin, alpha, cardiac muscle 1 15 34788096-34796139 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB003761, CAB037330, HPA041264, HPA041271 Supported Approved Actin filaments Tissue enriched 11 heart muscle: 2123.3 seminal vesicle: 189.9 -MORC3 KIAA0136, NXP2, ZCW5, ZCWCC3 ENSG00000159256 MORC family CW-type zinc finger 3 21 36320189-36386148 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018406, HPA034848 Approved Validated Nucleoplasm
Mitochondria Expressed in all endometrium: 30.7 -CHAF1B CAF-1, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7 ENSG00000159259 Chromatin assembly factor 1, subunit B (p60) 21 36385378-36419015 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021679, CAB033604 Approved Supported Nucleoplasm Mixed testis: 5.4 -CLDN14 DFNB29 ENSG00000159261 Claudin 14 21 36460621-36576569 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 11 kidney: 3.6;liver: 9.6 gallbladder: 0.6 -SIM2 bHLHe15, MGC119447, SIM ENSG00000159263 Single-minded family bHLH transcription factor 2 21 36699133-36749917 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA029295 Approved Supported Nucleoplasm
Nuclear bodies Tissue enhanced 0 esophagus: 22.9;kidney: 13.0 prostate: 9.1 -HLCS HCS ENSG00000159267 Holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 21 36750888-36990236 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017379 Approved Supported Cytosol Expressed in all parathyroid gland: 33.1 -GOLGA6A GLP, GOLGA6 ENSG00000159289 Golgin A6 family, member A 15 74069857-74082550 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044978, HPA050087 Supported Tissue enriched 9 testis: 21.4 liver: 2.4 -SCUBE1 ENSG00000159307 Signal peptide, CUB domain, EGF-like 1 22 43197283-43343388 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003190 Approved Tissue enhanced 0 ovary: 24.9 testis: 13.8 -ARHGAP27 CAMGAP1, FLJ43547, SH3D20, SH3P20 ENSG00000159314 Rho GTPase activating protein 27 17 45393902-45434421 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023919, HPA053053 Approved Supported Nucleus
Cytosol Mixed esophagus: 14.0 -ADPGK ADP-GK, DKFZp434B195 ENSG00000159322 ADP-dependent glucokinase 15 72751369-72785846 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045194, HPA058525 Approved Approved Centrosome Mixed lung: 25.3 -PTMS ParaT ENSG00000159335 Parathymosin 12 6765516-6770952 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038186 Approved Approved Nucleus
Nucleoli Expressed in all smooth muscle: 130.9 -PLA2G4D cPLA2delta ENSG00000159337 Phospholipase A2, group IVD (cytosolic) 15 42067009-42094554 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 26 prostate: 30.0;skin: 16.6 urinary bladder: 0.8 -PADI4 PAD, PADI5, PDI4, PDI5 ENSG00000159339 Peptidyl arginine deiminase, type IV 1 17308195-17364004 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017007, HPA042825 Supported Tissue enriched 12 bone marrow: 71.9 spleen: 6.0 -ADIPOR1 ACDCR1, PAQR1 ENSG00000159346 Adiponectin receptor 1 1 202940823-202958572 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all placenta: 135.5 -CYB5R1 humb5R2, NQO3A2 ENSG00000159348 Cytochrome b5 reductase 1 1 202961869-202967280 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010641, HPA014147 Supported Uncertain Nucleoli
Mitochondria
Cytosol Expressed in all skeletal muscle: 183.8 -PSMD4 AF, AF-1, Rpn10, S5A ENSG00000159352 Proteasome 26S subunit, non-ATPase 4 1 151254703-151267479 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038807, HPA039252, CAB047300 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 173.5 -ATP13A2 CLN12, HSA9947, PARK9 ENSG00000159363 ATPase type 13A2 1 16985958-17011928 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037038, CAB037111, HPA050910, HPA054717 Approved Expressed in all cerebral cortex: 75.0 -M1AP C2orf65, D6Mm5e, SPATA37 ENSG00000159374 Meiosis 1 associated protein 2 74557883-74648338 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045420, HPA059302 Uncertain Approved Nucleoli
Mitochondria Tissue enhanced 0 testis: 14.8 fallopian tube: 4.1 -PSMB4 HN3, PROS26 ENSG00000159377 Proteasome subunit beta 4 1 151399534-151401944 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006700 Approved Expressed in all fallopian tube: 272.2 -IRX6 IRX-3, IRX7 ENSG00000159387 Iroquois homeobox 6 16 55323760-55330760 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018332 Uncertain Approved Nucleus
Mitochondria Tissue enhanced 0 adipose tissue: 8.6 heart muscle: 4.0 -BTG2 MGC126063, MGC126064, PC3, TIS21 ENSG00000159388 BTG family, member 2 1 203305491-203309602 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA002355 Uncertain Approved Nucleoplasm
Vesicles Expressed in all ovary: 662.9 -CES5A CAUXIN, CES4C1, CES5, CES7, FLJ31547 ENSG00000159398 Carboxylesterase 5A 16 55846154-55956031 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047635 Uncertain Tissue enriched 40 epididymis: 78.9 liver: 1.9 -HK2 ENSG00000159399 Hexokinase 2 2 74833981-74893359 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028587 Approved Mixed epididymis: 79.1 -C1R ENSG00000159403 Complement component 1, r subcomponent 12 7080209-7092607 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001251, HPA001551 Uncertain Approved Nucleoplasm
Cytosol Expressed in all liver: 1216.5 -CELF3 BRUNOL1, CAGH4, ERDA4, MGC57297, TNRC4 ENSG00000159409 CUGBP, Elav-like family member 3 1 151702404-151716814 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006292 Uncertain Approved Nucleoplasm Group enriched 6 adrenal gland: 15.3;cerebral cortex: 51.8 stomach: 5.6 -ALDH4A1 ALDH4, P5CDh ENSG00000159423 Aldehyde dehydrogenase 4 family, member A1 1 18871430-18902781 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004645, HPA006401 Approved Tissue enhanced 0 kidney: 184.9;liver: 108.1 adipose tissue: 63.7 -STARD9 KIAA1300, KIF16A ENSG00000159433 StAR-related lipid transfer (START) domain containing 9 15 42575659-42720981 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014562, HPA038631 Uncertain Uncertain Microtubules
Cytosol Mixed testis: 14.5 -THEM4 CTMP ENSG00000159445 Thioesterase superfamily member 4 1 151873584-151909808 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028161 Approved Expressed in all kidney: 11.6 -TCHH THH ENSG00000159450 Trichohyalin 1 152106317-152115454 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028375 Uncertain Tissue enhanced 0 placenta: 1.6;spleen: 2.2 testis: 1.2 -LCE2B LEP10, SPRL1B, XP5 ENSG00000159455 Late cornified envelope 2B 1 152686123-152687401 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 10 skin: 564.3 breast: 55.3 -UBR1 ENSG00000159459 Ubiquitin protein ligase E3 component n-recognin 1 15 42942897-43106113 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038838 Approved Approved Nucleoplasm
Vesicles Expressed in all parathyroid gland: 26.9 -AMFR gp78, RNF45 ENSG00000159461 Autocrine motility factor receptor, E3 ubiquitin protein ligase 16 56361452-56425538 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026381, HPA029018, HPA077835 Approved Supported Endoplasmic reticulum
Golgi apparatus Expressed in all testis: 154.3 -MED8 ARC32, MGC17544, MGC19641 ENSG00000159479 Mediator complex subunit 8 1 43383917-43389808 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028377, HPA028438 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 41.5 -TGM7 TGMZ ENSG00000159495 Transglutaminase 7 15 43276280-43302255 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 6 testis: 1.5;tonsil: 1.5 esophagus: 0.2 -RGL4 Rgr ENSG00000159496 Ral guanine nucleotide dissociation stimulator-like 4 22 23688136-23699176 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA035979 Uncertain Tissue enhanced 0 bone marrow: 107.6 parathyroid gland: 48.1 -SPRR2G ENSG00000159516 Small proline-rich protein 2G 1 153149582-153150869 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 10 skin: 271.3 tonsil: 28.3 -PGLYRP3 PGLYRPIalpha, PGRP-Ialpha, PGRPIA ENSG00000159527 Peptidoglycan recognition protein 3 1 153297862-153310718 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA030369 Uncertain Group enriched 9 esophagus: 43.2;skin: 87.7 tonsil: 7.1 -ISL2 FLJ10160 ENSG00000159556 ISL LIM homeobox 2 15 76336724-76342476 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA075192 Approved Rods & Rings Not detected salivary gland: 0.8 -RSPRY1 KIAA1972 ENSG00000159579 Ring finger and SPRY domain containing 1 16 57186137-57240475 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003729 Approved Expressed in all testis: 39.4 -CCDC17 FLJ33084 ENSG00000159588 Coiled-coil domain containing 17 1 45620044-45624057 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028338 Approved Tissue enriched 17 fallopian tube: 53.8 lung: 3.2 -GPBP1L1 SP192 ENSG00000159592 GC-rich promoter binding protein 1-like 1 1 45627304-45688113 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028593 Approved Approved Nucleoplasm
Plasma membrane
Focal adhesion sites Expressed in all testis: 106.6 -NAE1 APPBP1, ula-1 ENSG00000159593 NEDD8 activating enzyme E1 subunit 1 16 66802875-66873256 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041178, HPA042041 Approved Approved Nucleus
Microtubules
Centrosome Expressed in all testis: 86.5 -TMEM69 C1orf154, FLJ21029 ENSG00000159596 Transmembrane protein 69 1 45687214-45694443 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026993 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 21.9 -ADGRG5 GPR114, PGR27 ENSG00000159618 Adhesion G protein-coupled receptor G5 16 57542421-57591681 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA007133 Supported Approved Nucleoplasm
Nuclear membrane
Vesicles Tissue enhanced 0 lymph node: 11.3;tonsil: 8.9 appendix: 6.2 -DRC7 C16orf50, CCDC135, CFAP50, DKFZp434I099, FAP50 ENSG00000159625 Dynein regulatory complex subunit 7 16 57694793-57731805 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041521 Uncertain Group enriched 17 fallopian tube: 32.4;testis: 81.1 parathyroid gland: 3.4 -ACE ACE1, CD143, DCP1 ENSG00000159640 Angiotensin I converting enzyme 17 63477061-63498380 Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002426, CAB002921, HPA029298, HPA069790 Supported Approved Vesicles Tissue enhanced 0 duodenum: 183.8;small intestine: 297.5 testis: 83.7 -TEPP ENSG00000159648 Testis, prostate and placenta expressed 16 57976435-57988116 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA062092 Supported Tissue enriched 9 testis: 7.3 thyroid gland: 0.7 -UROC1 FLJ31300, HMFN0320 ENSG00000159650 Urocanate hydratase 1 3 126481281-126517773 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036253, HPA036254 Uncertain Tissue enriched 119 liver: 43.0 fallopian tube: 0.3 -EFCAB14 KIAA0494 ENSG00000159658 EF-hand calcium binding domain 14 1 46675159-46719064 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011224, HPA011938 Supported Approved Nucleoli
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 299.7 -SPON2 DIL1 ENSG00000159674 Spondin 2, extracellular matrix protein 4 1166932-1208962 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040170, HPA066095 Uncertain Approved Vesicles Tissue enhanced 0 endometrium: 105.3;prostate: 96.8 cervix: 53.6 -CHCHD6 CHCM1, MGC13016, Mic25, PPP1R23 ENSG00000159685 Coiled-coil-helix-coiled-coil-helix domain containing 6 3 126704220-126960406 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047673, HPA051975 Approved Supported Mitochondria Expressed in all testis: 48.8 -CTBP1 BARS ENSG00000159692 C-terminal binding protein 1 4 1211448-1249953 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004217, HPA018987, HPA044971 Approved Validated Nucleoplasm Expressed in all cerebral cortex: 142.1 -LRRC36 FLJ11004 ENSG00000159708 Leucine rich repeat containing 36 16 67326798-67385203 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055237, HPA058479 Supported Tissue enriched 7 testis: 62.1 placenta: 8.7 -TPPP3 CGI-38, p20, p25gamma ENSG00000159713 Tubulin polymerization-promoting protein family member 3 16 67389809-67393535 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047629 Approved Approved Nucleoli fibrillar center Tissue enriched 6 fallopian tube: 1296.3 lung: 214.6 -ZDHHC1 C16orf1, HSU90653, ZNF377 ENSG00000159714 Zinc finger, DHHC-type containing 1 16 67394419-67416833 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042531, HPA048659 Uncertain Approved Cytosol Mixed fallopian tube: 31.4 -ATP6V0D1 ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD ENSG00000159720 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 16 67438014-67481237 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016938 Uncertain Expressed in all cerebral cortex: 187.6 -AGRP Agrt, ART, ASIP2 ENSG00000159723 Agouti related neuropeptide 16 67482571-67483813 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041017 Uncertain Tissue enhanced 0 adrenal gland: 5.8;epididymis: 24.7 lung: 3.0 -ZFYVE28 KIAA1643 ENSG00000159733 Zinc finger, FYVE domain containing 28 4 2269582-2418663 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038175, HPA057587 Approved Approved Nucleus
Plasma membrane
Cytosol Mixed cerebral cortex: 9.9 -RLTPR CARMIL2, LRRC16C ENSG00000159753 RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing 16 67644919-67657569 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041402 Approved Tissue enhanced 0 appendix: 16.8;lymph node: 25.3;spleen: 15.3 tonsil: 10.4 -C16orf86 FLJ41802 ENSG00000159761 Chromosome 16 open reading frame 86 16 67666816-67668758 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA073475 Supported Tissue enriched 7 testis: 27.5 parathyroid gland: 4.0 -PIP GCDFP-15, GCDFP15, GPIP4 ENSG00000159763 Prolactin-induced protein 7 143132077-143139746 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002661, HPA009177 Supported Group enriched 55 breast: 4413.0;salivary gland: 6961.2;seminal vesicle: 4142.4 prostate: 93.4 -FAM131B KIAA0773 ENSG00000159784 Family with sequence similarity 131, member B 7 143353400-143362770 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021371, HPA029992 Validated Nucleoplasm
Cytosol Tissue enriched 9 cerebral cortex: 64.0 parathyroid gland: 7.4 -RGS12 ENSG00000159788 Regulator of G-protein signaling 12 4 3293028-3439913 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054646, HPA067421 Supported Nucleus
Nucleoli Mixed cerebral cortex: 20.8 -PSKH1 ENSG00000159792 Protein serine kinase H1 16 67893272-67929678 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053927 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 48.6 -ZYX ENSG00000159840 Zyxin 7 143381080-143391111 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004835, CAB009321, HPA073497, CAB075747 Approved Supported Focal adhesion sites Expressed in all parathyroid gland: 388.9 -ABR MDB ENSG00000159842 Active BCR-related 17 1003518-1229021 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA053618, HPA054824 Approved Approved Nucleoplasm
Cytosol Mixed smooth muscle: 12.4 -LYPD5 FLJ30469 ENSG00000159871 LY6/PLAUR domain containing 5 19 43795929-43827206 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042511, HPA054670 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 skin: 43.8 testis: 12.3 -CCDC117 FLJ33814 ENSG00000159873 Coiled-coil domain containing 117 22 28772674-28789301 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000826 Uncertain Approved Nucleus
Microtubules
Cytosol Expressed in all testis: 67.5 -ZNF230 FDZF2 ENSG00000159882 Zinc finger protein 230 19 44002948-44013926 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA006172 Approved Mitochondria Mixed spleen: 5.1 -CCDC107 MGC31967 ENSG00000159884 Coiled-coil domain containing 107 9 35658290-35661511 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA016857, HPA050442 Validated Nucleoplasm
Plasma membrane Expressed in all adipose tissue: 63.0 -ZNF222 ENSG00000159885 Zinc finger protein 222 19 44025342-44033112 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA004086 Approved Approved Nucleoplasm
Nuclear bodies Mixed testis: 16.8 -NPR2 AMDM, ANPb, ANPRB, GUCY2B, NPRB ENSG00000159899 Natriuretic peptide receptor 2 9 35792154-35809732 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed endometrium: 30.7 -ZNF221 ENSG00000159905 Zinc finger protein 221 19 43951223-43967709 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA059435 Uncertain Approved Nuclear bodies Mixed parathyroid gland: 5.0 -ZNF233 FLJ38032 ENSG00000159915 Zinc finger protein 233 19 44259880-44275317 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA020975 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 26.5 cerebral cortex: 5.9 -ZNF235 ANF270, HZF6, ZFP93, ZNF270 ENSG00000159917 Zinc finger protein 235 19 44228729-44305046 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA045582 Uncertain Supported Nucleoplasm Mixed parathyroid gland: 6.2 -GNE IBM2, Uae1 ENSG00000159921 Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 9 36214441-36277056 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007045, HPA027258 Approved Supported Cytosol Expressed in all rectum: 54.2 -TNFRSF13C BAFFR, CD268 ENSG00000159958 Tumor necrosis factor receptor superfamily, member 13C 22 41922023-41926818 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA003246, CAB008380 Supported Uncertain Nucleus Group enriched 10 appendix: 23.8;lymph node: 46.7;spleen: 44.4;tonsil: 51.9 bone marrow: 4.0 -OR3A3 OR17-137, OR17-16, OR17-201, OR3A6, OR3A7, OR3A8P ENSG00000159961 Olfactory receptor, family 3, subfamily A, member 3 17 3420568-3421533 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected tonsil: 0.1 -ARHGAP35 GRF-1, GRLF1, KIAA1722, P190A, p190ARhoGAP, p190RhoGAP ENSG00000160007 Rho GTPase activating protein 35 19 46918676-47005077 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037311, HPA055184, HPA056470 Approved Supported Nuclear bodies
Aggresome Expressed in all testis: 96.5 -PTGIR IP ENSG00000160013 Prostaglandin I2 (prostacyclin) receptor (IP) 19 46620468-46625118 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lung: 14.0 appendix: 8.4 -CALM3 PHKD ENSG00000160014 Calmodulin 3 (phosphorylase kinase, delta) 19 46601074-46610793 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA044999 Approved Expressed in all cerebral cortex: 1317.4 -DFFA DFF-45, DFF1, DFF45, ICAD ENSG00000160049 DNA fragmentation factor, 45kDa, alpha polypeptide 1 10456522-10472526 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002679, HPA018859, HPA019938, HPA025230 Supported Supported Plasma membrane
Cytosol Expressed in all placenta: 28.8 -CCDC28B MGC1203, RP4-622L5.5 ENSG00000160050 Coiled-coil domain containing 28B 1 32200386-32205387 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028589 Uncertain Tissue enhanced 0 skeletal muscle: 40.8 testis: 23.4 -IQCC FLJ10547 ENSG00000160051 IQ motif containing C 1 32205661-32208687 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA028602, HPA028686 Approved Supported Vesicles Mixed testis: 11.8 -TMEM234 C1orf91, dJ622L5.7, FLJ90779, RP4-622L5 ENSG00000160055 Transmembrane protein 234 1 32214472-32222359 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA015049 Uncertain Approved Vesicles Mixed epididymis: 12.8 -BSDC1 FLJ10276, RP4-811H24.7 ENSG00000160058 BSD domain containing 1 1 32365103-32394731 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031358, HPA031360 Approved Validated Golgi apparatus Expressed in all parathyroid gland: 111.3 -ZBTB8A BOZF1, FLJ90065, ZBTB8, ZNF916A ENSG00000160062 Zinc finger and BTB domain containing 8A 1 32539427-32605939 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031768, HPA031769, HPA031770 Approved Approved Nuclear speckles
Focal adhesion sites Mixed endometrium: 10.2 -ATAD3B KIAA1273, TOB3 ENSG00000160072 ATPase family, AAA domain containing 3B 1 1471769-1497848 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058968, HPA064867, HPA065305 Approved Supported Mitochondria Mixed appendix: 7.7 -SSU72 HSPC182 ENSG00000160075 SSU72 homolog, RNA polymerase II CTD phosphatase 1 1541673-1574869 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069290, HPA070604 Supported Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 148.9 -UBE2J2 NCUBE2, Ubc6p ENSG00000160087 Ubiquitin-conjugating enzyme E2, J2 1 1253909-1273885 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 115.1 -ZNF362 FLJ25476, lin-29, RN ENSG00000160094 Zinc finger protein 362 1 33256545-33300719 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059239 Uncertain Approved Nucleus
Nucleoli Expressed in all spleen: 22.6 -FNDC5 FRCP2 ENSG00000160097 Fibronectin type III domain containing 5 1 32862268-32872482 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051290 Approved Tissue enhanced 0 skeletal muscle: 109.1 heart muscle: 29.7 -CPAMD8 K-CAP, KIAA1283, VIP ENSG00000160111 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 19 16892947-17026815 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031327, HPA031328, HPA031329, HPA031330 Uncertain Uncertain Focal adhesion sites Tissue enhanced 0 seminal vesicle: 51.4 prostate: 23.3 -NR2F6 EAR-2, ERBAL2 ENSG00000160113 Nuclear receptor subfamily 2, group F, member 6 19 17231883-17245940 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed duodenum: 31.8 -ANKLE1 ANKRD41, FLJ39369, LEMD6 ENSG00000160117 Ankyrin repeat and LEM domain containing 1 19 17281645-17287646 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA026789, HPA073498 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 bone marrow: 13.8 lymph node: 3.7 -CCDC58 FLJ33273 ENSG00000160124 Coiled-coil domain containing 58 3 122359591-122383231 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047777, HPA051965 Approved Approved Nucleoli
Mitochondria Expressed in all kidney: 47.1 -VMA21 MEAX, XMEA ENSG00000160131 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) X 151396515-151409364 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010972 Uncertain Expressed in all cerebral cortex: 30.1 -KALRN ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD ENSG00000160145 Kalirin, RhoGEF kinase 3 124080023-124726325 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011913, CAB026456 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 51.5 spleen: 12.0 -CILP2 MGC45771 ENSG00000160161 Cartilage intermediate layer protein 2 19 19538248-19546659 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041847 Uncertain Tissue enhanced 0 gallbladder: 2.5;testis: 4.2 adipose tissue: 0.8 -ABCG1 ABC8 ENSG00000160179 ATP-binding cassette, sub-family G (WHITE), member 1 21 42199689-42297244 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031470, HPA031471 Approved Supported Golgi apparatus
Vesicles Expressed in all spleen: 43.7 -TFF3 HITF, ITF ENSG00000160180 Trefoil factor 3 (intestinal) 21 42311667-42315651 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB020681, HPA035464 Supported Approved Nucleus
Nucleoli Tissue enhanced 0 cervix, uterine: 467.4;colon: 507.1;rectum: 511.3;thyroid gland: 618.6 small intestine: 466.0 -TFF2 SML1 ENSG00000160181 Trefoil factor 2 21 42346357-42351128 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025834, HPA036705 Supported Group enriched 29 duodenum: 1057.0;stomach: 5161.6 gallbladder: 107.8 -TFF1 BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 ENSG00000160182 Trefoil factor 1 21 42362282-42366594 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002170, HPA003425 Supported Tissue enriched 32 stomach: 6481.5 gallbladder: 204.1 -TMPRSS3 DFNB10, DFNB8 ENSG00000160183 Transmembrane protease, serine 3 21 42371890-42396846 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 fallopian tube: 34.9 stomach: 14.5 -UBASH3A CLIP4, STS-2, TULA ENSG00000160185 Ubiquitin associated and SH3 domain containing A 21 42403447-42447681 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lymph node: 12.7 appendix: 6.9 -RSPH1 CILD24, FLJ32753, RSP44, RSPH10A, TSGA2 ENSG00000160188 Radial spoke head 1 homolog (Chlamydomonas) 21 42472486-42496354 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016816, HPA017382 Supported Approved Nucleoplasm Tissue enriched 6 fallopian tube: 249.5 testis: 42.2 -SLC37A1 ENSG00000160190 Solute carrier family 37 (glucose-6-phosphate transporter), member 1 21 42496008-42581440 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030418, CAB034154 Approved Approved Nucleus Mixed duodenum: 46.9 -PDE9A ENSG00000160191 Phosphodiesterase 9A 21 42653636-42775509 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011380 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 prostate: 57.3 spleen: 25.9 -WDR4 TRM82, TRMT82 ENSG00000160193 WD repeat domain 4 21 42843094-42879568 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017381 Uncertain Supported Nucleus
Cytosol Mixed lymph node: 11.0 -NDUFV3 CI-10k ENSG00000160194 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 21 42879644-42913304 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019791, HPA020463, HPA030427, CAB034142 Supported Validated Mitochondria Expressed in all skeletal muscle: 29.0 -PKNOX1 PREP1 ENSG00000160199 PBX/knotted 1 homeobox 1 21 42974510-43033931 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004285, HPA057215, HPA065017 Approved Validated Nucleoplasm Mixed thyroid gland: 16.8 -CBS HIP4 ENSG00000160200 Cystathionine-beta-synthase 21 43053191-43076943 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001223 Supported Approved Nucleoli
Vesicles Tissue enhanced 0 liver: 56.7;ovary: 31.1 cerebral cortex: 19.9 -U2AF1 RN, RNU2AF1, U2AF35, U2AFBP ENSG00000160201 U2 small nuclear RNA auxiliary factor 1 21 43092956-43107587 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044833, HPA052083 Supported Validated Nucleoplasm Expressed in all thyroid gland: 71.4 -CRYAA CRYA1, HSPB4 ENSG00000160202 Crystallin, alpha A 21 43169008-43172805 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037737 Approved Nucleoplasm
Cytosol Tissue enriched 7 kidney: 12.4 liver: 1.7 -HSF2BP ENSG00000160207 Heat shock transcription factor 2 binding protein 21 43529192-43659493 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031724 Approved Nucleus
Cytosol Tissue enriched 9 testis: 40.6 cerebral cortex: 4.4 -RRP1B KIAA0179, Nnp1, PPP1R136, RRP1 ENSG00000160208 Ribosomal RNA processing 1B 21 43659548-43696079 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017893, HPA020324 Supported Validated Nucleoli Expressed in all testis: 21.7 -PDXK C21orf124, C21orf97, FLJ21324, FLJ31940, MGC15873, PKH, PNK, PRED79 ENSG00000160209 Pyridoxal (pyridoxine, vitamin B6) kinase 21 43719094-43762307 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030196, HPA030197, HPA030198, CAB033918 Approved Validated Nucleus Expressed in all cerebral cortex: 47.6 -G6PD G6PD1 ENSG00000160211 Glucose-6-phosphate dehydrogenase X 154531391-154547572 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000247, HPA000834 Supported Approved Vesicles
Microtubule organizing center
Cytosol Expressed in all testis: 107.0 -CSTB CST6, EPM1, PME, STFB ENSG00000160213 Cystatin B (stefin B) 21 43772512-43776445 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017380, CAB047320, HPA058557 Supported Supported Nucleoli
Cytosol Tissue enriched 8 esophagus: 1836.3 tonsil: 237.3 -RRP1 D21S2056E, NNP-1, Nop52, RRP1A ENSG00000160214 Ribosomal RNA processing 1 21 43789513-43805293 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016818, HPA018166 Approved Validated Nucleoli Expressed in all cerebral cortex: 12.1 -AGPAT3 LPAAT-gamma ENSG00000160216 1-acylglycerol-3-phosphate O-acyltransferase 3 21 43865186-43986536 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all small intestine: 58.7 -TRAPPC10 EHOC-1, TMEM1, TRS130 ENSG00000160218 Trafficking protein particle complex 10 21 44012319-44106552 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050423 Supported Expressed in all parathyroid gland: 14.1 -GAB3 ENSG00000160219 GRB2-associated binding protein 3 X 154675249-154751583 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA010090 Approved Mixed spleen: 18.0 -C21orf33 D21S2048E, ES1, GT335, HES1, KNP-I, KNP-Ia, KNPH, KNPI ENSG00000160221 Chromosome 21 open reading frame 33 21 44133605-44145723 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018517 Supported Expressed in all kidney: 35.3 -ICOSLG B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653 ENSG00000160223 Inducible T-cell co-stimulator ligand 21 44222991-44240966 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026037 Uncertain Supported Mitochondria Mixed bone marrow: 10.3 -AIRE APECED, APS1, PGA1 ENSG00000160224 Autoimmune regulator 21 44285838-44298648 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level HPA038267 Uncertain Not detected lymph node: 0.3 -C21orf2 A2, LRRC76, YF5 ENSG00000160226 Chromosome 21 open reading frame 2 21 44328944-44339402 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030284, CAB034126, CAB034128 Supported Approved Nucleoplasm Expressed in all cerebral cortex: 18.0 -ZNF66 FLJ16537, ZNF66P ENSG00000160229 Zinc finger protein 66 19 20776304-20807322 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 ovary: 9.8 thyroid gland: 3.9 -LRRC3 C21orf102 ENSG00000160233 Leucine rich repeat containing 3 21 44455486-44462196 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA017975 Uncertain Mixed liver: 4.1 -ITGB2 CD18, LFA-1, MAC-1, MFI7 ENSG00000160255 Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 21 44885953-44931989 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008877, HPA016894 Supported Approved Cytosol Expressed in all appendix: 246.8 -FAM207A C21orf70, PRED56 ENSG00000160256 Family with sequence similarity 207, member A 21 44940010-44976989 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034178, HPA036354 Approved Approved Golgi apparatus
Vesicles Expressed in all testis: 20.8 -RALGDS RalGEF, RGDS, RGF ENSG00000160271 Ral guanine nucleotide dissociation stimulator 9 133097720-133149334 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA025961, CAB032582 Approved Approved Nucleus Expressed in all cerebral cortex: 53.0 -FTCD ENSG00000160282 Formimidoyltransferase cyclodeaminase 21 46136262-46155567 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020073, HPA030928, HPA030929, HPA036114 Supported Approved Plasma membrane
Cytosol Group enriched 18 kidney: 100.1;liver: 184.7 testis: 7.7 -SPATC1L C21orf56 ENSG00000160284 Spermatogenesis and centriole associated 1-like 21 46161148-46184476 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018979, HPA019165, HPA029394 Uncertain Approved Vesicles
Plasma membrane
Cytosol Tissue enhanced 0 testis: 11.7 prostate: 6.4 -LSS OSC ENSG00000160285 Lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 21 46188141-46228824 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032060, HPA032062, CAB034116 Supported Approved Cytosol Expressed in all prostate: 35.2 -VAV2 ENSG00000160293 Vav 2 guanine nucleotide exchange factor 9 133761894-133992604 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003224 Uncertain Approved Vesicles Mixed adrenal gland: 32.3 -MCM3AP GANP, KIAA0572, Map80, SAC3 ENSG00000160294 Minichromosome maintenance complex component 3 associated protein 21 46235126-46286297 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021527, HPA032103 Approved Supported Nucleus
Nuclear membrane
Cytosol Expressed in all parathyroid gland: 35.1 -C21orf58 ENSG00000160298 Chromosome 21 open reading frame 58 21 46300181-46323875 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA035110, HPA035111 Uncertain Supported Nucleoplasm
Nuclear bodies Tissue enhanced 0 fallopian tube: 41.7 testis: 9.0 -PCNT KEN, KIAA0402, PCN, PCNT2, PCNTB, SCKL4 ENSG00000160299 Pericentrin 21 46324122-46445769 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016820, HPA019887, HPA032101 Supported Validated Centrosome Mixed skeletal muscle: 24.3 -DIP2A C21orf106, Dip2, KIAA0184 ENSG00000160305 Disco-interacting protein 2 homolog A 21 46458899-46569852 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052516 Uncertain Approved Nucleus Expressed in all testis: 13.9 -S100B S100beta ENSG00000160307 S100 calcium binding protein B 21 46598962-46605208 Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000073, HPA015768, CAB078196 Supported Approved Nucleus
Vesicles Group enriched 9 adipose tissue: 208.2;cerebral cortex: 628.0 seminal vesicle: 49.1 -PRMT2 HRMT1L1, MGC111373 ENSG00000160310 Protein arginine methyltransferase 2 21 46635167-46665124 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018976, HPA029591 Uncertain Validated Nucleoplasm
Cytosol Expressed in all ovary: 98.0 -CLDND2 MGC33839 ENSG00000160318 Claudin domain containing 2 19 51367098-51369003 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056971 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 22.3 spleen: 6.4 -ZNF208 PMIDP, ZNF95 ENSG00000160321 Zinc finger protein 208 19 21932958-22010949 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed testis: 16.8 -ADAMTS13 C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP ENSG00000160323 ADAM metallopeptidase with thrombospondin type 1 motif, 13 9 133414358-133459402 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042014, HPA042844 Uncertain Mixed liver: 6.2 -CACFD1 C9orf7, D9S2135, flower ENSG00000160325 Calcium channel flower domain containing 1 9 133459965-133470848 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015280 Approved Nucleoplasm Expressed in all thyroid gland: 16.6 -SLC2A6 GLUT6, GLUT9, HSA011372 ENSG00000160326 Solute carrier family 2 (facilitated glucose transporter), member 6 9 133471095-133479137 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042272, CAB046014 Uncertain Mixed appendix: 6.3 -ZNF761 FLJ16231, FLJ35333, KIAA2033 ENSG00000160336 Zinc finger protein 761 19 53431993-53458261 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Expressed in all prostate: 94.4 -FCN2 EBP-37, FCNL, ficolin-2, P35 ENSG00000160339 Ficolin (collagen/fibrinogen domain containing lectin) 2 9 134880812-134887520 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 5 liver: 54.8 breast: 10.2 -C9orf116 MGC29761, PIERCE1, RbEST47 ENSG00000160345 Chromosome 9 open reading frame 116 9 135495181-135501734 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA021439 Uncertain Approved Nucleoplasm
Cytosol Group enriched 6 epididymis: 30.7;fallopian tube: 152.6;testis: 63.0 thyroid gland: 13.6 -LCN1 MGC71975, PMFA, TLC, TP, VEGP ENSG00000160349 Lipocalin 1 9 135521438-135526532 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 fallopian tube: 3.0;seminal vesicle: 12.1 prostate: 1.4 -ZNF714 ENSG00000160352 Zinc finger protein 714 19 21082159-21125270 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 thyroid gland: 26.0 ovary: 21.9 -GPSM1 AGS3, DKFZP727I051 ENSG00000160360 G-protein signaling modulator 1 9 136327476-136359605 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042199 Uncertain Supported Nucleoplasm
Golgi apparatus Mixed cerebral cortex: 28.8 -C19orf47 FLJ36888 ENSG00000160392 Chromosome 19 open reading frame 47 19 40319536-40348527 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041843, HPA046309 Uncertain Validated Nucleoplasm Expressed in all skeletal muscle: 63.6 -HIPK4 FLJ32818 ENSG00000160396 Homeodomain interacting protein kinase 4 19 40379271-40390187 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA027733 Uncertain Group enriched 22 cerebral cortex: 4.7;testis: 14.7 seminal vesicle: 0.4 -CFAP157 C9orf117 ENSG00000160401 Cilia and flagella associated protein 157 9 127706989-127716002 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA021474, HPA021786 Supported Validated Plasma membrane
Cytosol Tissue enriched 8 fallopian tube: 93.9 lung: 12.2 -TOR2A FLJ14771, TORP1 ENSG00000160404 Torsin family 2, member A 9 127731524-127735317 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed bone marrow: 16.6 -ST6GALNAC6 SIAT7F, ST6GALNACVI ENSG00000160408 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 9 127885321-127905408 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018890 Approved Approved Nucleus Expressed in all rectum: 156.5 -SHKBP1 PP203, Sb1 ENSG00000160410 SH3KBP1 binding protein 1 19 40576851-40591399 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041887 Uncertain Approved Cell Junctions Expressed in all spleen: 54.3 -RDH13 SDR7C3 ENSG00000160439 Retinol dehydrogenase 13 (all-trans/9-cis) 19 55039108-55071291 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042006 Uncertain Supported Mitochondria
Cytosol Mixed placenta: 3.6 -ZER1 C9orf60, Hzyg, ZYG, ZYG11BL ENSG00000160445 Zyg-11 related, cell cycle regulator 9 128729786-128772414 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048464 Approved Cytosol Expressed in all cerebral cortex: 71.7 -ZDHHC12 FLJ14524, ZNF400 ENSG00000160446 Zinc finger, DHHC-type containing 12 9 128720869-128724127 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059339 Uncertain Approved Nucleoplasm Expressed in all small intestine: 36.5 -PKN3 PKNbeta, UTDP4-1 ENSG00000160447 Protein kinase N3 9 128702523-128720918 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045390, HPA058305 Uncertain Approved Vesicles Mixed adipose tissue: 7.6 -SPTBN4 KIAA1642, SPTBN3 ENSG00000160460 Spectrin, beta, non-erythrocytic 4 19 40466241-40576464 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054481 Approved Approved Nucleus
Nucleoli Tissue enriched 6 cerebral cortex: 18.7 adrenal gland: 2.9 -BRSK1 KIAA1811 ENSG00000160469 BR serine/threonine kinase 1 19 55282072-55312533 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021212, HPA061719 Supported Supported Nucleoplasm Tissue enriched 6 cerebral cortex: 138.2 parathyroid gland: 23.8 -COX6B2 COXVIB2, CT59, FLJ32865 ENSG00000160471 Cytochrome c oxidase subunit VIb polypeptide 2 (testis) 19 55349306-55354814 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA035014 Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enriched 14 testis: 74.6 rectum: 5.4 -TMEM190 MDAC1 ENSG00000160472 Transmembrane protein 190 19 55376836-55378244 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 9 fallopian tube: 228.8 testis: 26.5 -NLRP4 CLR19.5, CT58, FLJ32126, NALP4, PAN2, PYPAF4, RNH2 ENSG00000160505 NLR family, pyrin domain containing 4 19 55836578-55881854 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042561 Uncertain Tissue enhanced 0 testis: 12.6;tonsil: 4.8 lymph node: 2.0 -PLPP7 C9orf67, FLJ14662, MGC12921, NET39, PPAPDC3 ENSG00000160539 Phospholipid phosphatase 7 (inactive) 9 131289694-131309262 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA070252 Uncertain Approved Nucleus
Vesicles Group enriched 5 heart muscle: 33.8;skeletal muscle: 72.2 cerebral cortex: 10.1 -TAOK1 FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1 ENSG00000160551 TAO kinase 1 17 29390464-29551904 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007669 Approved Expressed in all parathyroid gland: 40.8 -MED27 CRSP34, CRSP8, MED3, TRAP37 ENSG00000160563 Mediator complex subunit 27 9 131860107-132079908 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007002 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all testis: 29.1 -DEDD2 FLAME-3 ENSG00000160570 Death effector domain containing 2 19 42198598-42220140 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043419 Approved Nucleoplasm Mixed spleen: 12.0 -SIK3 FLJ12240, KIAA0999, L19, QSK ENSG00000160584 SIK family kinase 3 11 116843402-117098437 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045245, HPA048161 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 43.0 -MPZL3 ENSG00000160588 Myelin protein zero-like 3 11 118226690-118252350 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029116 Approved Golgi apparatus Mixed skin: 25.9 -AMICA1 AMICA, Gm638 ENSG00000160593 Adhesion molecule, interacts with CXADR antigen 1 11 118193740-118225094 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047919 Approved Tissue enhanced 0 appendix: 84.3 spleen: 68.0 -NEK8 NPHP9 ENSG00000160602 NIMA-related kinase 8 17 28725897-28743455 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040661, HPA040679 Approved Mixed thyroid gland: 9.6 -TLCD1 ENSG00000160606 TLC domain containing 1 17 28724348-28727935 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042366 Approved Mixed fallopian tube: 23.1 -PCSK7 LPC, PC7, PC8, SPC7 ENSG00000160613 Proprotein convertase subtilisin/kexin type 7 11 117204337-117232525 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043181, HPA052957 Uncertain Nucleus
Nuclear membrane
Nucleoli Expressed in all smooth muscle: 305.0 -SAFB HET, SAFB1 ENSG00000160633 Scaffold attachment factor B 19 5623035-5668478 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001969, HPA016832, HPA020076 Supported Validated Nucleoplasm Expressed in all spleen: 54.9 -CD3G ENSG00000160654 CD3g molecule, gamma (CD3-TCR complex) 11 118344344-118355161 CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017520, HPA038494 Supported Tissue enhanced 0 lymph node: 31.8;tonsil: 19.7 spleen: 16.3 -S100A1 S100-alpha, S100A ENSG00000160678 S100 calcium binding protein A1 1 153627926-153632039 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002599, HPA006462 Supported Group enriched 5 heart muscle: 1764.2;skeletal muscle: 996.0 thyroid gland: 267.1 -CHTOP C1orf77, DKFZP547E1010, FOP, SRAG ENSG00000160679 Chromatin target of PRMT1 1 153633982-153646306 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028647, HPA030540 Approved Validated Nuclear speckles Expressed in all endometrium: 61.7 -CXCR5 BLR1, CD185, MDR15 ENSG00000160683 Chemokine (C-X-C motif) receptor 5 11 118883766-118897799 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB026149, HPA042432 Supported Tissue enhanced 0 lymph node: 32.9;spleen: 21.7;tonsil: 16.2 appendix: 15.1 -ZBTB7B c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B ENSG00000160685 Zinc finger and BTB domain containing 7B 1 155002630-155018522 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006811, HPA025820 Approved Validated Nucleoplasm Expressed in all skin: 89.6 -FLAD1 FAD1, PP591 ENSG00000160688 Flavin adenine dinucleotide synthetase 1 1 154983338-154993111 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028476, HPA028486, HPA028563 Approved Supported Plasma membrane
Cytosol Expressed in all skin: 28.6 -SHC1 p66, SHC, ShcA ENSG00000160691 SHC (Src homology 2 domain containing) transforming protein 1 1 154962298-154974395 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001844, CAB005374, CAB016305 Supported Validated Cytosol Expressed in all adipose tissue: 161.1 -VPS11 PEP5, RNF108 ENSG00000160695 Vacuolar protein sorting 11 homolog (S. cerevisiae) 11 119067692-119081978 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039020 Approved Approved Cytosol Expressed in all parathyroid gland: 26.0 -NLRX1 CLR11.3, NOD9 ENSG00000160703 NLR family member X1 11 119166568-119184016 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061516 Supported Supported Plasma membrane
Cell Junctions
Mitochondria Expressed in all esophagus: 37.9 -ADAR ADAR1, G1P1, IFI4 ENSG00000160710 Adenosine deaminase, RNA-specific 1 154582062-154627999 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003890, HPA051519, CAB056157 Supported Validated Nucleus
Nucleoli Expressed in all spleen: 122.7 -IL6R CD126 ENSG00000160712 Interleukin 6 receptor 1 154405193-154469450 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all appendix: 34.4 -UBE2Q1 NICE-5, PRO3094, UBE2Q ENSG00000160714 Ubiquitin-conjugating enzyme E2Q family member 1 1 154548577-154559028 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063368 Approved Approved Nucleoplasm
Centrosome Expressed in all testis: 56.8 -CHRNB2 ENSG00000160716 Cholinergic receptor, nicotinic, beta 2 (neuronal) 1 154567781-154580026 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 14 cerebral cortex: 22.0 adrenal gland: 1.5 -CRTC2 TORC2 ENSG00000160741 CREB regulated transcription coactivator 2 1 153947669-153958625 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028454, HPA028465 Supported Validated Nucleoplasm Expressed in all spleen: 36.6 -ANO10 FLJ10375, MGC47890, SCAR10, TMEM16K ENSG00000160746 Anoctamin 10 3 43354859-43691594 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051569 Approved Expressed in all duodenum: 64.3 -FDPS ENSG00000160752 Farnesyl diphosphate synthase 1 155308748-155320666 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028200 Approved Approved Nucleoplasm
Cytosol Expressed in all liver: 186.1 -RUSC1 NESCA ENSG00000160753 RUN and SH3 domain containing 1 1 155320896-155331114 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028510, HPA029922, HPA029923 Approved Supported Cytosol Expressed in all cerebral cortex: 38.6 -FAM189B C1orf2, cote1 ENSG00000160767 Family with sequence similarity 189, member B 1 155247205-155255483 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA006659, HPA050674 Uncertain Supported Nucleoplasm Mixed seminal vesicle: 6.7 -PAQR6 FLJ22672, PRdelta ENSG00000160781 Progestin and adipoQ receptor family member VI 1 156243321-156248117 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA073505 Approved Nucleus
Nucleoli Tissue enriched 9 cerebral cortex: 97.8 skin: 10.8 -PMF1 ENSG00000160783 Polyamine-modulated factor 1 1 156212993-156240042 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034583, HPA071854 Supported Nucleoplasm
Vesicles Expressed in all thyroid gland: 68.4 -SLC25A44 FLJ90431, KIAA0446 ENSG00000160785 Solute carrier family 25, member 44 1 156193932-156212796 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA065411 Approved Nucleus
Mitochondria Expressed in all cerebral cortex: 43.1 -LMNA CMD1A, HGPS, LGMD1B, LMN1, LMNL1, PRO1 ENSG00000160789 Lamin A/C 1 156082573-156140089 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004022, HPA006660 Supported Expressed in all gallbladder: 344.5 -CCR5 CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 ENSG00000160791 Chemokine (C-C motif) receptor 5 (gene/pseudogene) 3 46370854-46376206 CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed appendix: 20.9 -NBEAL2 KIAA0540 ENSG00000160796 Neurobeachin-like 2 3 46979683-47009703 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051969 Approved Expressed in all bone marrow: 76.7 -CCDC12 MGC23918 ENSG00000160799 Coiled-coil domain containing 12 3 46921726-46982010 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056814, HPA060530 Approved Supported Nucleoplasm Expressed in all lymph node: 58.9 -PTH1R PTHR, PTHR1 ENSG00000160801 Parathyroid hormone 1 receptor 3 46877746-46903799 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA007978 Approved Tissue enhanced 0 kidney: 158.5 adrenal gland: 36.8 -UBQLN4 A1U, C1orf6, UBIN ENSG00000160803 Ubiquilin 4 1 156035301-156053794 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061797 Approved Supported Nucleus Expressed in all cerebral cortex: 41.2 -MYL3 CMH8, MLC1SB, MLC1V, VLC1 ENSG00000160808 Myosin, light chain 3, alkali; ventricular, skeletal, slow 3 46857872-46882169 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016564, CAB018662, HPA046859, HPA063034 Supported Approved Vesicles Group enriched 10 heart muscle: 1364.5;skeletal muscle: 1730.5 esophagus: 158.2 -PPP1R35 C7orf47, MGC22793 ENSG00000160813 Protein phosphatase 1, regulatory subunit 35 7 100435282-100436565 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021604, HPA051607 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 35.0 spleen: 18.2 -GPATCH4 DKFZP434F1735, FLJ20249, GPATC4 ENSG00000160818 G patch domain containing 4 1 156594487-156601496 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028323, HPA054319 Approved Supported Nucleus
Nucleoli Expressed in all parathyroid gland: 34.2 -LRRC71 C1orf92, FLJ32884 ENSG00000160838 Leucine rich repeat containing 71 1 156920650-156933094 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 9 fallopian tube: 19.9;testis: 22.2 lung: 2.3 -FCRL3 CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e ENSG00000160856 Fc receptor-like 3 1 157674321-157700857 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA015508 Approved Group enriched 12 appendix: 18.8;lymph node: 56.6;spleen: 37.3;tonsil: 33.6 urinary bladder: 2.9 -AZGP1 ZA2G, ZAG ENSG00000160862 Alpha-2-glycoprotein 1, zinc-binding 7 99966720-99976157 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012582, CAB016087, CAB032276 Supported Tissue enhanced 0 breast: 1188.3;liver: 1270.8;prostate: 1556.6;salivary gland: 1431.4 kidney: 292.6 -FGFR4 CD334, JTK2 ENSG00000160867 Fibroblast growth factor receptor 4 5 177086886-177098144 Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005196, HPA027273, HPA027369, HPA028251 Approved Tissue enhanced 0 lung: 39.1 duodenum: 22.0 -CYP3A4 CYP3A3 ENSG00000160868 Cytochrome P450, family 3, subfamily A, polypeptide 4 7 99756960-99784265 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033671, HPA072245 Supported Uncertain Cytosol Group enriched 200 duodenum: 849.6;liver: 2446.6;small intestine: 990.4 adrenal gland: 7.1 -CYP3A7 CP37, P450-HFLA ENSG00000160870 Cytochrome P450, family 3, subfamily A, polypeptide 7 7 99705037-99735196 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072245 Uncertain Cytosol Tissue enriched 14 liver: 143.0 kidney: 9.8 -NACC1 BEND8, BTBD14B, BTBD30, NAC-1, NAC1 ENSG00000160877 Nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 19 13118103-13141141 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021238, HPA062245 Supported Validated Nucleoplasm Expressed in all cerebral cortex: 37.2 -CYP11B1 CPN1, CYP11B, FHI, P450C11 ENSG00000160882 Cytochrome P450, family 11, subfamily B, polypeptide 1 8 142872356-142879846 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049171, HPA056348, HPA057752 Supported Tissue enriched 936 adrenal gland: 1879.5 testis: 2.0 -HK3 ENSG00000160883 Hexokinase 3 (white cell) 5 176880869-176899332 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056743 Supported Tissue enhanced 0 bone marrow: 88.0 spleen: 28.4 -LY6K CT97, FLJ35226, HSJ001348 ENSG00000160886 Lymphocyte antigen 6 complex, locus K 8 142700111-142705127 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017770, CAB075742, CAB075743 Supported Supported Nucleoplasm
Plasma membrane Tissue enriched 5 testis: 30.4 adipose tissue: 5.9 -IER2 ETR101 ENSG00000160888 Immediate early response 2 19 13150415-13154908 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA055387, HPA060574 Validated Nucleoplasm Expressed in all fallopian tube: 159.7 -ZNF394 FLJ12298, ZKSCAN14, ZSCAN46 ENSG00000160908 Zinc finger protein 394 7 99486519-99500324 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA051421, HPA054639 Uncertain Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 62.2 -CPSF4 CPSF30, NAR ENSG00000160917 Cleavage and polyadenylation specific factor 4, 30kDa 7 99438922-99457371 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049094, HPA066470 Uncertain Supported Nucleoplasm Expressed in all testis: 43.8 -LY6E RIG-E, SCA-2, TSA-1 ENSG00000160932 Lymphocyte antigen 6 complex, locus E 8 143017982-143023832 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all lung: 109.5 -VPS28 ENSG00000160948 Vacuolar protein sorting 28 homolog (S. cerevisiae) 8 144423601-144428563 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024688, HPA024745 Supported Expressed in all fallopian tube: 234.2 -TONSL IKBR, NFKBIL2 ENSG00000160949 Tonsoku-like, DNA repair protein 8 144428775-144444444 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024679, HPA046494 Uncertain Validated Nucleoplasm
Nuclear bodies Mixed bone marrow: 5.4 -PTGER1 EP1 ENSG00000160951 Prostaglandin E receptor 1 (subtype EP1), 42kDa 19 14472466-14475362 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 kidney: 2.9;spleen: 2.6 lung: 0.7 -MUM1 EXPAND1, MUM-1 ENSG00000160953 Melanoma associated antigen (mutated) 1 19 1285893-1378431 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048063 Uncertain Approved Nucleus
Cytosol Expressed in all testis: 60.9 -RECQL4 RecQ4 ENSG00000160957 RecQ helicase-like 4 8 144511288-144517845 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level CAB017800, HPA025821 Supported Validated Nucleus Mixed testis: 17.4 -LRRC14 KIAA0014, LRRC14A ENSG00000160959 Leucine rich repeat containing 14 8 144517992-144525178 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021047 Uncertain Approved Nucleoplasm
Cytosol Expressed in all prostate: 25.0 -ZNF333 KIAA1806 ENSG00000160961 Zinc finger protein 333 19 14689801-14733746 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043973, HPA054680 Uncertain Approved Nucleoplasm Mixed endometrium: 11.2 -COL26A1 EMI6, EMID2, Emu2 ENSG00000160963 Collagen, type XXVI, alpha 1 7 101362820-101559024 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA027059 Approved Approved Vesicles Tissue enhanced 0 cerebral cortex: 10.2;parathyroid gland: 5.5 prostate: 2.9 -PPP1R16A MGC14333, MYPT3 ENSG00000160972 Protein phosphatase 1, regulatory subunit 16A 8 144477969-144502121 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023755 Uncertain Approved Plasma membrane Expressed in all duodenum: 27.9 -FOXH1 FAST1 ENSG00000160973 Forkhead box H1 8 144473412-144476335 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 rectum: 2.3 colon: 1.0 -ORAI2 C7orf19, CBCIP2, FLJ12474, FLJ14733, H_NH0514P08.8, TMEM142B ENSG00000160991 ORAI calcium release-activated calcium modulator 2 7 102433106-102456821 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055137, HPA065937 Uncertain Approved Nucleus Mixed appendix: 43.3 -ALKBH4 FLJ20013 ENSG00000160993 AlkB homolog 4, lysine demthylase 7 102456238-102464876 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051422 Approved Expressed in all cerebral cortex: 10.1 -CCDC105 FLJ40365 ENSG00000160994 Coiled-coil domain containing 105 19 15010744-15023269 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058585 Approved Tissue enriched 104 testis: 11.7 skin: 0.1 -SH2B2 APS ENSG00000160999 SH2B adaptor protein 2 7 102285091-102321711 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051131 Uncertain Validated Cytosol Mixed skeletal muscle: 12.9 -C5orf45 DKFZp686L2452, LOC51149, MGC65027, MGC78537 ENSG00000161010 Chromosome 5 open reading frame 45 5 179835133-179862173 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043975 Uncertain Approved Plasma membrane
Cytosol Mixed fallopian tube: 21.2 -SQSTM1 A170, OSIL, p60, p62, p62B, PDB3 ENSG00000161011 Sequestosome 1 5 179806398-179838078 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004587, HPA064165 Approved Validated Vesicles
Cytosol Expressed in all thyroid gland: 376.5 -MGAT4B GnT-Ivb ENSG00000161013 Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 5 179797597-179806952 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052134 Uncertain Expressed in all small intestine: 314.0 -RPL8 L8 ENSG00000161016 Ribosomal protein L8 8 144789765-144792587 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045095, HPA050165 Supported Validated Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 954.9 -MAML1 KIAA0200, Mam-1 ENSG00000161021 Mastermind-like transcriptional coactivator 1 5 179732850-179796511 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037687, HPA057531 Approved Validated Nucleoplasm Expressed in all endometrium: 22.9 -PGLYRP2 PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like ENSG00000161031 Peptidoglycan recognition protein 2 19 15468645-15498956 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033468, HPA043568, HPA046311, HPA075237 Approved Approved Cell Junctions Tissue enriched 17 liver: 132.5 testis: 7.8 -LRWD1 CENP-33, DKFZp434K1815, ORCA ENSG00000161036 Leucine-rich repeats and WD repeat domain containing 1 7 102464929-102473168 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021320, HPA029916 Supported Approved Nucleus
Cytosol Tissue enriched 11 testis: 209.1 fallopian tube: 18.5 -FBXL13 DRC6, Fbl13, MGC21636 ENSG00000161040 F-box and leucine-rich repeat protein 13 7 102813230-103074843 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057232 Uncertain Group enriched 5 fallopian tube: 7.8;testis: 37.2 stomach: 4.3 -NAPEPLD C7orf18, FMP30, NAPE-PLD ENSG00000161048 N-acyl phosphatidylethanolamine phospholipase D 7 103099776-103149560 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019832, HPA024338 Approved Validated Cytosol Mixed cerebral cortex: 11.2 -SCGB3A1 HIN-1, HIN1, LU105, PnSP-2, UGRP2 ENSG00000161055 Secretoglobin, family 3A, member 1 5 180590103-180591540 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 breast: 124.9;cervix, uterine: 343.4;lung: 303.2;salivary gland: 193.8 stomach: 42.4 -PSMC2 MSS1, Nbla10058, S7 ENSG00000161057 Proteasome 26S subunit, ATPase 2 7 103344254-103369395 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019238, HPA049621 Approved Supported Cytosol
Cytoplasmic bodies Expressed in all thyroid gland: 72.0 -CELF5 BRUNOL5 ENSG00000161082 CUGBP, Elav-like family member 5 19 3224703-3297076 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042012, HPA060336 Supported Tissue enriched 7 cerebral cortex: 38.2 ovary: 5.1 -MFSD12 C19orf28, MGC20700, PP3501 ENSG00000161091 Major facilitator superfamily domain containing 12 19 3538261-3574290 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042149, HPA043088 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all skin: 64.2 -USP41 ENSG00000161133 Ubiquitin specific peptidase 41 22 20350578-20390758 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected cerebral cortex: 0.3 -YDJC ENSG00000161179 YdjC homolog (bacterial) 22 21628089-21630064 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061005 Approved Nucleoplasm Mixed small intestine: 2.7 -CCDC116 FLJ36046 ENSG00000161180 Coiled-coil domain containing 116 22 21632716-21637327 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 30 testis: 23.2 placenta: 0.7 -DVL3 KIAA0208 ENSG00000161202 Dishevelled segment polarity protein 3 3 184155388-184173610 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046486, HPA058265 Approved Approved Intermediate filaments
Midbody ring
Centrosome Expressed in all placenta: 55.0 -AP2M1 AP50, CLAPM1, mu2 ENSG00000161203 Adaptor-related protein complex 2, mu 1 subunit 3 184174689-184184091 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036849, HPA069870 Uncertain Supported Plasma membrane Expressed in all cerebral cortex: 559.2 -ABCF3 EST201864 ENSG00000161204 ATP-binding cassette, sub-family F (GCN20), member 3 3 184186023-184194012 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036332 Approved Approved Nucleoli
Cytosol Expressed in all parathyroid gland: 74.8 -PCYT1A CT, CTPCT, PCYT1 ENSG00000161217 Phosphate cytidylyltransferase 1, choline, alpha 3 196214222-196287957 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035428 Approved Approved Nucleus Expressed in all duodenum: 69.0 -FBXO27 Fbg5, Fbx27 ENSG00000161243 F-box protein 27 19 38990714-39032785 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046800, HPA062242 Approved Approved Nucleoplasm Tissue enhanced 0 skin: 22.8 esophagus: 8.5 -DMKN ZD52F10 ENSG00000161249 Dermokine 19 35497220-35513658 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029406 Supported Approved Nucleoplasm
Cytosol Tissue enriched 16 skin: 3989.4 breast: 256.2 -U2AF1L4 MGC33901, U2AF1L3, U2af26 ENSG00000161265 U2 small nuclear RNA auxiliary factor 1-like 4 19 35742464-35745445 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA052083, HPA061644 Supported Approved Nucleoplasm Mixed testis: 7.7 -BDH1 BDH, SDR9C1 ENSG00000161267 3-hydroxybutyrate dehydrogenase, type 1 3 197509783-197573323 Candidate cardiovascular disease genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030947, HPA058709 Approved Validated Mitochondria Tissue enriched 6 liver: 168.8 colon: 27.4 -NPHS1 CNF, NPHN ENSG00000161270 Nephrosis 1, congenital, Finnish type (nephrin) 19 35825964-35869287 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB035555 Supported Tissue enhanced 0 kidney: 17.7;lymph node: 5.5;pancreas: 5.5 tonsil: 2.4 -THAP8 FLJ32891 ENSG00000161277 THAP domain containing 8 19 36034985-36054762 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA064056, HPA070139 Approved Nucleoplasm Mixed testis: 9.0 -COX7A1 COX7A, COX7AH ENSG00000161281 Cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 19 36150922-36152869 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 heart muscle: 347.0;skeletal muscle: 1078.3 adipose tissue: 117.6 -ZNF382 FLJ14686, KS1 ENSG00000161298 Zinc finger protein 382 19 36604817-36634113 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049259 Approved Approved Nuclear speckles Mixed cerebral cortex: 10.9 -LRRC56 DKFZp761L1518, FLJ00101 ENSG00000161328 Leucine rich repeat containing 56 11 537527-554916 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA038728 Uncertain Tissue enhanced 0 testis: 3.9 epididymis: 1.5 -PLXDC1 TEM3, TEM7 ENSG00000161381 Plexin domain containing 1 17 39063303-39154394 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012805 Approved Mixed gallbladder: 22.9 -PGAP3 CAB2, MGC9753, PER1, PERLD1, PP1498 ENSG00000161395 Post-GPI attachment to proteins 3 17 39671122-39696797 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA016591 Approved Approved Plasma membrane
Cytosol Expressed in all thyroid gland: 35.5 -IKZF3 Aiolos, ZNFN1A3 ENSG00000161405 IKAROS family zinc finger 3 (Aiolos) 17 39757715-39864188 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017105, HPA024377 Supported Uncertain Plasma membrane
Cytosol Tissue enhanced 0 lymph node: 45.2;spleen: 32.2;tonsil: 40.9 appendix: 26.4 -GRIN2C GluN2C, NMDAR2C ENSG00000161509 Glutamate receptor, ionotropic, N-methyl D-aspartate 2C 17 74842023-74861504 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 9.6;heart muscle: 7.8;thyroid gland: 14.0 salivary gland: 4.4 -FDXR ADXR ENSG00000161513 Ferredoxin reductase 17 74862497-74873031 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009818, HPA044393, HPA053673 Supported Validated Mitochondria Tissue enriched 6 adrenal gland: 233.0 testis: 39.2 -SAP30BP HCNGP, HTRG, HTRP ENSG00000161526 SAP30 binding protein 17 75667116-75708062 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042382, HPA052943 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 29.1 -ACOX1 PALMCOX ENSG00000161533 Acyl-CoA oxidase 1, palmitoyl 17 75941507-75979363 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021094, HPA021192, HPA021195, HPA028759 Approved Validated Nucleus
Vesicles Expressed in all liver: 98.4 -PRPSAP1 PAP39 ENSG00000161542 Phosphoribosyl pyrophosphate synthetase-associated protein 1 17 76309486-76384521 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062396 Approved Cytosol Expressed in all thyroid gland: 82.1 -CYGB HGB, STAP ENSG00000161544 Cytoglobin 17 76527356-76551175 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017757, HPA061642 Approved Validated Nuclear speckles Expressed in all adipose tissue: 46.6 -SRSF2 PR264, SC-35, SC35, SFRS2, SFRS2A ENSG00000161547 Serine/arginine-rich splicing factor 2 17 76734115-76737374 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049905 Supported Approved Nucleus
Cytosol Expressed in all lymph node: 128.8 -ZNF577 MGC4400 ENSG00000161551 Zinc finger protein 577 19 51855802-51890950 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA041499, HPA046761 Uncertain Supported Nucleus
Nucleoli Expressed in all testis: 42.1 -TMEM143 FLJ10922 ENSG00000161558 Transmembrane protein 143 19 48332356-48364237 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014476 Uncertain Approved Nucleoli fibrillar center Tissue enhanced 0 skeletal muscle: 32.5 heart muscle: 15.9 -KLHL10 FLJ32662 ENSG00000161594 Kelch-like family member 10 17 41835685-41848384 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067538 Supported Tissue enriched 49 testis: 89.6 epididymis: 1.8 -CCDC155 FLJ32658, KASH5 ENSG00000161609 Coiled-coil domain containing 155 19 49388218-49417994 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019937, HPA019940 Approved Tissue enriched 135 testis: 56.9 pancreas: 0.4 -HCRT OX, PPOX ENSG00000161610 Hypocretin (orexin) neuropeptide precursor 17 42184060-42185452 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB004758 Uncertain Not detected adipose tissue: 0.1 -ALDH16A1 MGC10204 ENSG00000161618 Aldehyde dehydrogenase 16 family, member A1 19 49453169-49471048 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059488 Approved Supported Mitochondria Expressed in all spleen: 17.9 -DCD AIDD, DCD-1, DSEP, HCAP, PIF ENSG00000161634 Dermcidin 12 54644591-54648493 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063967 Supported Tissue enriched 94 breast: 332.5 skeletal muscle: 3.5 -ITGA5 CD49e, FNRA ENSG00000161638 Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 12 54395261-54419460 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002642, CAB009008 Supported Expressed in all smooth muscle: 482.6 -SIGLEC11 ENSG00000161640 Sialic acid binding Ig-like lectin 11 19 49948985-49961172 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060278 Approved Group enriched 7 ovary: 79.9;spleen: 32.2 adrenal gland: 8.2 -ZNF385A DKFZp586G1122, Hzf, ZFP385, ZNF385 ENSG00000161642 Zinc finger protein 385A 12 54369133-54391298 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039799 Supported Nucleus
Cytosol Tissue enhanced 0 skin: 170.2 cerebral cortex: 66.3 -MPP3 DLG3 ENSG00000161647 Membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 17 43800799-43833170 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021818, HPA024742 Uncertain Approved Nucleoplasm
Cytosol Mixed cerebral cortex: 2.9 -CD300LG CLM9, Trem4 ENSG00000161649 CD300 molecule-like family member g 17 43847148-43863629 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 adipose tissue: 142.8;placenta: 85.6;testis: 33.9 lung: 17.3 -IZUMO2 C19orf41, MGC33947, SCRL ENSG00000161652 IZUMO family member 2 19 50152548-50163195 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042143 Uncertain Tissue enriched 255 testis: 55.9 thyroid gland: 0.2 -NAGS AGAS, ARGA, NAT7 ENSG00000161653 N-acetylglutamate synthase 17 44004546-44009063 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027300 Supported Mitochondria Tissue enhanced 0 duodenum: 15.2;small intestine: 13.9 parathyroid gland: 5.4 -LSM12 FLJ30656 ENSG00000161654 LSM12 homolog 17 44034635-44067619 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051934 Approved Approved Cytosol Expressed in all testis: 49.0 -ASB16 FLJ30165 ENSG00000161664 Ankyrin repeat and SOCS box containing 16 17 44170447-44179083 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA066834 Approved Focal adhesion sites Tissue enhanced 0 skeletal muscle: 23.2 parathyroid gland: 7.2 -EMC10 C19orf63, HSM1, HSS1, INM02 ENSG00000161671 ER membrane protein complex subunit 10 19 50476400-50490870 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053905 Uncertain Expressed in all skeletal muscle: 63.9 -JOSD2 SBBI54 ENSG00000161677 Josephin domain containing 2 19 50505998-50511353 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 16.8 -SHANK1 SPANK-1, SSTRIP, synamon ENSG00000161681 SH3 and multiple ankyrin repeat domains 1 19 50661827-50719450 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032129, HPA032130 Uncertain Supported Plasma membrane Tissue enriched 24 cerebral cortex: 35.9 adrenal gland: 1.5 -FAM171A2 MGC34829 ENSG00000161682 Family with sequence similarity 171, member A2 17 44353215-44363875 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019770 Uncertain Tissue enhanced 0 cerebral cortex: 13.4 epididymis: 3.3 -DBF4B ASKL1, chifb, DRF1, FLJ13087, ZDBF1B ENSG00000161692 DBF4 zinc finger B 17 44708608-44752264 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048465 Uncertain Supported Nucleus Mixed testis: 5.7 -PLCD3 ENSG00000161714 Phospholipase C, delta 3 17 45108967-45133354 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025711 Approved Approved Plasma membrane Mixed colon: 29.9 -FMNL3 DKFZp762B245, MGC45819, WBP3 ENSG00000161791 Formin-like 3 12 49636499-49708165 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002552, HPA023201 Uncertain Supported Golgi apparatus
Vesicles
Plasma membrane
Cytosol Mixed lymph node: 28.4 -AQP5 ENSG00000161798 Aquaporin 5 12 49961870-49965681 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065008 Supported Approved Plasma membrane Group enriched 8 salivary gland: 257.1;stomach: 54.0;testis: 176.5 breast: 21.0 -RACGAP1 MgcRacGAP ENSG00000161800 Rac GTPase activating protein 1 12 49976923-50033136 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025859, HPA039427, HPA043912 Supported Validated Nucleoplasm Tissue enhanced 0 testis: 84.3 lymph node: 28.9 -OR7G1 OR19-15, OR7G1P ENSG00000161807 Olfactory receptor, family 7, subfamily G, member 1 19 9114828-9115763 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -LARP4 PP13296 ENSG00000161813 La ribonucleoprotein domain family, member 4 12 50392383-50480004 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039306, HPA039673 Approved Validated Cytosol Expressed in all adrenal gland: 36.8 -GRASP Tamalin ENSG00000161835 GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 12 52006940-52015889 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA040664, HPA062028 Approved Approved Nuclear bodies
Vesicles Mixed adipose tissue: 21.5 -RAVER1 KIAA1978 ENSG00000161847 Ribonucleoprotein, PTB-binding 1 19 10316212-10333640 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043575, HPA049457 Supported Supported Nucleoplasm Mixed small intestine: 20.6 -KRT84 Hb-4, KRTHB4 ENSG00000161849 Keratin 84, type II 12 52377812-52385652 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039714 Supported Not detected tonsil: 0.5 -KRT82 Hb-2, KRTHB2 ENSG00000161850 Keratin 82, type II 12 52393931-52406355 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA058715, HPA067230 Supported Not detected testis: 0.1 -SYCE2 CESC1 ENSG00000161860 Synaptonemal complex central element protein 2 19 12898786-12919276 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042080, HPA062919 Supported Supported Nucleus Tissue enriched 15 testis: 38.8 cerebral cortex: 2.5 -SPC24 FLJ90806, SPBC24 ENSG00000161888 SPC24, NDC80 kinetochore complex component 19 11131520-11155808 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051234 Approved Supported Nucleus
Nucleoli Mixed bone marrow: 16.6 -IP6K3 IHPK3, INSP6K3 ENSG00000161896 Inositol hexakisphosphate kinase 3 6 33721670-33746905 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA053644 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 skeletal muscle: 32.4;thyroid gland: 21.7 heart muscle: 8.2 -LEMD2 dJ482C21.1, NET25 ENSG00000161904 LEM domain containing 2 6 33771202-33789136 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017340 Approved Validated Nuclear membrane Expressed in all parathyroid gland: 68.5 -ALOX15 15-LOX-1 ENSG00000161905 Arachidonate 15-lipoxygenase 17 4630902-4642294 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004962, CAB004963, HPA013859 Approved Tissue enhanced 0 fallopian tube: 19.3;lung: 9.9 breast: 4.6 -TREML1 dJ238O23.3, TLT1 ENSG00000161911 Triggering receptor expressed on myeloid cells-like 1 6 41149342-41154337 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016700, HPA017860 Supported Tissue enhanced 0 lymph node: 6.6 bone marrow: 5.0 -ZNF653 Zip67 ENSG00000161914 Zinc finger protein 653 19 11483427-11505923 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA023631, HPA023635 Uncertain Approved Nucleus
Cytosol Mixed testis: 19.0 -MED11 HSPC296, MGC88387 ENSG00000161920 Mediator complex subunit 11 17 4731428-4733610 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056669 Uncertain Approved Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 49.1 -CXCL16 CXCLG16, SR-PSOX, SRPSOX ENSG00000161921 Chemokine (C-X-C motif) ligand 16 17 4733526-4739922 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA053253, HPA066315 Approved Approved Golgi apparatus
Vesicles Mixed lung: 106.3 -SCIMP C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783 ENSG00000161929 SLP adaptor and CSK interacting membrane protein 17 5208961-5234860 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006117 Supported Tissue enhanced 0 spleen: 69.8 lymph node: 46.6 -RNASEK-C17orf49 ENSG00000161939 RNASEK-C17orf49 readthrough 17 7012635-7017520 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA022961, HPA024457 Approved Uncertain Nucleoplasm
Cytosol Tissue enhanced 0 testis: 1.0 endometrium: 0.9 -BCL6B BAZF, ZBTB28, ZNF62 ENSG00000161940 B-cell CLL/lymphoma 6, member B 17 7023020-7030290 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059147 Uncertain Mixed adipose tissue: 34.5 -ASGR2 CLEC4H2 ENSG00000161944 Asialoglycoprotein receptor 2 17 7101322-7115700 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014899, HPA015998 Supported Supported Endoplasmic reticulum
Plasma membrane Tissue enriched 11 liver: 317.4 gallbladder: 28.1 -TNFSF13 APRIL, CD256 ENSG00000161955 Tumor necrosis factor (ligand) superfamily, member 13 17 7558292-7561608 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA004863 Uncertain Expressed in all lung: 150.0 -SENP3 DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3, Ulp1 ENSG00000161956 SUMO1/sentrin/SMT3 specific peptidase 3 17 7561875-7571969 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060290 Supported Supported Nucleus
Nucleoli Expressed in all testis: 57.1 -FGF11 FHF3, FLJ16061, MGC102953, MGC45269 ENSG00000161958 Fibroblast growth factor 11 17 7438273-7444937 Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA066605 Approved Centrosome Tissue enhanced 0 adrenal gland: 34.8;skin: 27.6 cerebral cortex: 20.7 -EIF4A1 DDX2A, EIF-4A, EIF4A ENSG00000161960 Eukaryotic translation initiation factor 4A1 17 7572706-7579005 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011689, HPA068286 Uncertain Approved Cytosol Expressed in all smooth muscle: 452.3 -RPL26 L26 ENSG00000161970 Ribosomal protein L26 17 8377520-8383213 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030449, CAB037301 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all breast: 5169.8 -CCDC42 CCDC42A, FLJ32734 ENSG00000161973 Coiled-coil domain containing 42 17 8729934-8745219 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 357 testis: 128.7 spleen: 0.3 -POLR3K RPC11 ENSG00000161980 Polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 16 46407-53628 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005891 Approved Uncertain Nucleus
Cytosol Expressed in all lymph node: 20.8 -SNRNP25 C16orf33 ENSG00000161981 Small nuclear ribonucleoprotein 25kDa (U11/U12) 16 53010-57669 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041183, HPA044248 Uncertain Supported Nucleoplasm
Cytokinetic bridge
Cytosol Expressed in all cerebral cortex: 55.6 -PRR35 C16orf11 ENSG00000161992 Proline rich 35 16 560422-565528 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA069297 Uncertain Tissue enhanced 0 kidney: 2.9 testis: 0.8 -WDR90 C16orf15, C16orf16, C16orf17, C16orf18, C16orf19, FLJ36483, KIAA1924 ENSG00000161996 WD repeat domain 90 16 649311-667833 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049362, HPA061785 Approved Approved Nuclear speckles Mixed testis: 28.3 -JMJD8 C16orf20 ENSG00000161999 Jumonji domain containing 8 16 681671-684528 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all parathyroid gland: 59.8 -CCDC78 C16orf25, FLJ34512 ENSG00000162004 Coiled-coil domain containing 78 16 722582-726954 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 11 fallopian tube: 95.2 lung: 8.5 -MSLNL C16orf37, MPFL ENSG00000162006 Mesothelin-like 16 769428-783370 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Not detected epididymis: 0.7 -SSTR5 ENSG00000162009 Somatostatin receptor 5 16 1078781-1080142 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA066503 Supported Plasma membrane Tissue enhanced 0 adrenal gland: 1.2 heart muscle: 0.8 -SPSB3 C16orf31, SSB-3 ENSG00000162032 SplA/ryanodine receptor domain and SOCS box containing 3 16 1776712-1793700 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046602 Approved Approved Mitochondria Expressed in all adrenal gland: 29.2 -MEIOB C16orf73, MGC35212 ENSG00000162039 Meiosis specific with OB domains 16 1833983-1884294 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042547 Approved Nucleus
Nucleoli Tissue enriched 51 testis: 70.9 kidney: 1.3 -HS3ST6 HS3ST5 ENSG00000162040 Heparan sulfate (glucosamine) 3-O-sulfotransferase 6 16 1911463-1918440 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 10 skin: 9.5 fallopian tube: 0.9 -C16orf59 FLJ13909 ENSG00000162062 Chromosome 16 open reading frame 59 16 2460080-2464963 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051394 Uncertain Approved Nucleoplasm
Cell Junctions Tissue enhanced 0 testis: 5.5 lymph node: 2.6 -CCNF FBX1, FBXO1 ENSG00000162063 Cyclin F 16 2429394-2458854 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060596, HPA070495, HPA071600 Supported Supported Centrosome Mixed tonsil: 9.1 -TBC1D24 DFNA65, DFNB86, KIAA1171, TLDC6 ENSG00000162065 TBC1 domain family, member 24 16 2475118-2505734 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044712, HPA068080 Uncertain Supported Plasma membrane
Cell Junctions Expressed in all cerebral cortex: 23.4 -AMDHD2 CGI-14 ENSG00000162066 Amidohydrolase domain containing 2 16 2520357-2531422 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041184, HPA041321 Approved Approved Nucleoli
Cytosol Mixed testis: 15.9 -NTN3 NTN2L ENSG00000162068 Netrin 3 16 2471499-2474145 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050817 Uncertain Not detected testis: 0.6 -CCDC64B ENSG00000162069 Coiled-coil domain containing 64B 16 3027682-3036926 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043251 Uncertain Approved Intermediate filaments
Actin filaments
Cytosol Tissue enhanced 0 skin: 28.6 stomach: 17.4 -PAQR4 FLJ30002 ENSG00000162073 Progestin and adipoQ receptor family member IV 16 2969245-2973489 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA068394 Approved Vesicles Tissue enhanced 0 cerebral cortex: 54.1;parathyroid gland: 64.2 skin: 19.2 -FLYWCH2 ENSG00000162076 FLYWCH family member 2 16 2883186-2899382 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041354 Uncertain Approved Nucleus Expressed in all spleen: 35.8 -ZG16B HRPE773, JCLN2, PRO1567 ENSG00000162078 Zymogen granule protein 16B 16 2830169-2839585 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041125, HPA053549 Supported Approved Nucleoplasm
Vesicles Tissue enriched 210 salivary gland: 19669.3 prostate: 93.6 -ZNF75A FLJ31529 ENSG00000162086 Zinc finger protein 75a 16 3305406-3318852 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA001665 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center Expressed in all parathyroid gland: 45.5 -ADCY9 AC9 ENSG00000162104 Adenylate cyclase 9 16 3953387-4116185 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041328, HPA044225 Approved Approved Cytosol Mixed thyroid gland: 31.8 -SHANK2 CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3 ENSG00000162105 SH3 and multiple ankyrin repeat domains 2 11 70467856-71252577 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008174 Approved Tissue enhanced 0 cerebral cortex: 20.2 thyroid gland: 11.2 -CLPB ANKCLB, FLJ13152, HSP78, SKD3 ENSG00000162129 ClpB homolog, mitochondrial AAA ATPase chaperonin 11 72292425-72434680 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039005, HPA039006, HPA064571 Approved Tissue enriched 10 testis: 175.4 parathyroid gland: 18.1 -NEU3 ENSG00000162139 Sialidase 3 (membrane sialidase) 11 74988134-75018893 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038729, HPA038730, HPA070381 Uncertain Supported Nucleoplasm
Vesicles Mixed parathyroid gland: 25.0 -CYB561A3 CYBASC3 ENSG00000162144 Cytochrome b561 family, member A3 11 61348745-61362299 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052548 Uncertain Expressed in all adrenal gland: 188.0 -PPP1R32 C11orf66, FLJ32771, IIIG9 ENSG00000162148 Protein phosphatase 1, regulatory subunit 32 11 61481120-61490931 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039067, HPA039068 Supported Tissue enhanced 0 fallopian tube: 64.0;testis: 87.4 epididymis: 15.2 -ASRGL1 ALP, ALP1, FLJ22316 ENSG00000162174 Asparaginase like 1 11 62337448-62393412 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029725, HPA055572, CAB070192 Supported Approved Nucleoplasm
Microtubules Expressed in all cervix: 180.8 -GNG3 ENSG00000162188 Guanine nucleotide binding protein (G protein), gamma 3 11 62707658-62709201 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enriched 16 cerebral cortex: 316.2 adrenal gland: 19.1 -UBXN1 2B28, LOC51035, SAKS1, UBXD10 ENSG00000162191 UBX domain protein 1 11 62676498-62679117 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012669 Approved Approved Nucleoplasm Expressed in all ovary: 145.7 -LBHD1 C11orf48, MGC2477 ENSG00000162194 LBH domain containing 1 11 62662817-62672255 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012127, HPA023592 Approved Approved Nucleoplasm
Cytosol Mixed parathyroid gland: 9.6 -TTC9C MGC29649 ENSG00000162222 Tetratricopeptide repeat domain 9C 11 62728069-62740293 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055169 Approved Approved Nucleoplasm Expressed in all thyroid gland: 30.9 -TAF6L PAF65A ENSG00000162227 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 11 62771303-62787342 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067239 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 12.0 -NXF1 DKFZp667O0311, Mex67, TAP ENSG00000162231 Nuclear RNA export factor 1 11 62792123-62806302 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016327, HPA061593 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 144.9 -STX5 SED5, STX5A ENSG00000162236 Syntaxin 5 11 62806897-62832088 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001358 Uncertain Supported Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 58.9 -SLC25A45 ENSG00000162241 Solute carrier family 25, member 45 11 65375192-65383701 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA050821 Uncertain Approved Nucleoplasm
Cytosol Expressed in all spleen: 12.6 -RPL29 HIP, HUMRPL29, L29, RPL29P10 ENSG00000162244 Ribosomal protein L29 3 51993600-51995942 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069064 Approved Validated Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 2735.7 -ITIH3 H3P ENSG00000162267 Inter-alpha-trypsin inhibitor heavy chain 3 3 52794768-52809009 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017373 Approved Tissue enriched 50 liver: 413.4 spleen: 8.2 -SYVN1 DER3, HRD1 ENSG00000162298 Synovial apoptosis inhibitor 1, synoviolin 11 65121780-65134533 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005480, HPA024300, CAB037030 Supported Supported Nucleoplasm
Endoplasmic reticulum
Plasma membrane Expressed in all tonsil: 76.7 -ZFPL1 D11S750, MCG4 ENSG00000162300 Zinc finger protein-like 1 11 65084223-65088400 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014909, HPA017347 Supported Validated Golgi apparatus Expressed in all fallopian tube: 31.5 -RPS6KA4 MSK2, RSK-B ENSG00000162302 Ribosomal protein S6 kinase, 90kDa, polypeptide 4 11 64359148-64372215 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008649, HPA023225 Approved Supported Nucleus
Cytosol Expressed in all spleen: 23.6 -LRP5 BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2 ENSG00000162337 Low density lipoprotein receptor-related protein 5 11 68312609-68449275 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013001, HPA030505 Approved Expressed in all small intestine: 50.8 -TPCN2 TPC2 ENSG00000162341 Two pore segment channel 2 11 69048897-69090604 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016561, HPA027080 Supported Approved Nucleoli Mixed endometrium: 11.7 -FGF19 ENSG00000162344 Fibroblast growth factor 19 11 69698232-69704642 Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036082 Approved Tissue enriched 27 gallbladder: 263.2 small intestine: 9.5 -CYP4A22 ENSG00000162365 Cytochrome P450, family 4, subfamily A, polypeptide 22 1 47137435-47149741 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 15 kidney: 33.4;liver: 109.0 epididymis: 4.6 -PDZK1IP1 DD96, MAP17, SPAP ENSG00000162366 PDZK1 interacting protein 1 1 47183593-47191044 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014907 Approved Approved Nuclear speckles
Cytosol Group enriched 6 gallbladder: 299.6;kidney: 1048.6 esophagus: 121.8 -TAL1 bHLHa17, SCL, TCL5 ENSG00000162367 T-cell acute lymphocytic leukemia 1 1 47216290-47232220 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017805, HPA047866 Approved Approved Nucleus Tissue enhanced 0 bone marrow: 17.7 placenta: 10.0 -CMPK1 CMPK, UMP-CMPK ENSG00000162368 Cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 1 47333797-47378839 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053730, HPA058604 Approved Supported Nucleus Expressed in all small intestine: 172.6 -BEND5 C1orf165, FLJ11588 ENSG00000162373 BEN domain containing 5 1 48727523-48776969 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054347, HPA058007 Uncertain Approved Nuclear speckles
Cytosol Mixed cerebral cortex: 6.0 -ELAVL4 HUD, PNEM ENSG00000162374 ELAV like neuron-specific RNA binding protein 4 1 50048014-50203786 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004442 Supported Group enriched 8 adrenal gland: 10.8;cerebral cortex: 53.5;testis: 10.8 appendix: 2.9 -COA7 C1orf163, FLJ12439, RESA1, SELRC1 ENSG00000162377 Cytochrome c oxidase assembly factor 7 (putative) 1 52684451-52698366 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028154, HPA029926 Approved Approved Nucleus
Mitochondria Expressed in all cerebral cortex: 14.7 -ZYG11B FLJ13456, ZYG11 ENSG00000162378 Zyg-11 family member B, cell cycle regulator 1 52726467-52827342 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028156 Uncertain Approved Golgi apparatus
Intermediate filaments Expressed in all cerebral cortex: 29.0 -SLC1A7 EAAT5 ENSG00000162383 Solute carrier family 1 (glutamate transporter), member 7 1 53087179-53142632 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 gallbladder: 8.5 fallopian tube: 4.4 -C1orf123 FLJ20580 ENSG00000162384 Chromosome 1 open reading frame 123 1 53214099-53220617 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043835 Uncertain Approved Cytosol Expressed in all smooth muscle: 88.1 -MAGOH MAGOH1, MAGOHA ENSG00000162385 Mago homolog, exon junction complex core component 1 53226892-53238610 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015425, HPA043036, HPA047754 Approved Supported Nucleus Expressed in all lymph node: 83.5 -ACOT11 BFIT, BFIT1, KIAA0707, STARD14, THEA, THEM1 ENSG00000162390 Acyl-CoA thioesterase 11 1 54542257-54639192 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041047 Approved Supported Cytosol Mixed duodenum: 37.8 -FAM151A C1orf179, MGC27169 ENSG00000162391 Family with sequence similarity 151, member A 1 54609182-54623556 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA016840 Approved Uncertain Nucleoplasm Group enriched 14 kidney: 175.6;small intestine: 68.0 liver: 8.5 -PARS2 DKFZp727A071 ENSG00000162396 Prolyl-tRNA synthetase 2, mitochondrial (putative) 1 54756898-54764514 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028308, HPA028314, HPA028518 Uncertain Approved Nucleoli fibrillar center
Mitochondria Mixed testis: 8.0 -LEXM C1orf177, FLJ40201, LEM ENSG00000162398 Lymphocyte expansion molecule 1 54806063-54842252 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035889, HPA035890 Uncertain Group enriched 5 esophagus: 10.5;testis: 7.0 duodenum: 1.7 -BSND BART, DFNB73 ENSG00000162399 Barttin CLCNK-type chloride channel accessory beta subunit 1 54998933-55010883 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053836 Supported Tissue enriched 6 kidney: 10.2 salivary gland: 1.5 -USP24 KIAA1057 ENSG00000162402 Ubiquitin specific peptidase 24 1 55066359-55215113 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026723, HPA028428, HPA067124 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 37.4 -PLPP3 LPP3, PAP-2b, PPAP2B ENSG00000162407 Phospholipid phosphatase 3 1 56494747-56645301 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028892, HPA072751 Uncertain Supported Golgi apparatus Expressed in all thyroid gland: 543.7 -NOL9 FLJ23323, Grc3, NET6 ENSG00000162408 Nucleolar protein 9 1 6521347-6554535 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036347 Supported Nucleoli
Intermediate filaments Mixed spleen: 8.6 -PRKAA2 AMPK, AMPKa2, PRKAA ENSG00000162409 Protein kinase, AMP-activated, alpha 2 catalytic subunit 1 56645322-56715335 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044540 Approved Approved Nuclear speckles
Golgi apparatus Tissue enhanced 0 heart muscle: 27.3 parathyroid gland: 14.8 -KLHL21 KIAA0469 ENSG00000162413 Kelch-like family member 21 1 6590724-6614607 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051364, HPA059307 Uncertain Supported Centrosome Expressed in all seminal vesicle: 39.0 -ZSWIM5 KIAA1511 ENSG00000162415 Zinc finger, SWIM-type containing 5 1 45016399-45306209 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018211 Uncertain Approved Nuclear speckles Mixed parathyroid gland: 15.5 -GMEB1 P96PIF, PIF96 ENSG00000162419 Glucocorticoid modulatory element binding protein 1 1 28668732-28719353 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044811, HPA052975 Supported Validated Nucleoplasm Mixed bone marrow: 8.6 -SLC45A1 DNB5 ENSG00000162426 Solute carrier family 45, member 1 1 8317826-8344167 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 11.7 endometrium: 3.2 -SEPN1 MDRS1, RSMD1, RSS, selN ENSG00000162430 Selenoprotein N, 1 1 25800176-25818224 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058076 Approved Supported Cytosol Expressed in all smooth muscle: 80.2 -AK4 AK3, AK3L1 ENSG00000162433 Adenylate kinase 4 1 65147549-65232145 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042753, HPA049461 Supported Supported Mitochondria Tissue enhanced 0 kidney: 189.1 liver: 53.6 -JAK1 JAK1A, JAK1B, JTK3 ENSG00000162434 Janus kinase 1 1 64833229-64966504 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013088 Approved Expressed in all lymph node: 117.1 -RAVER2 FLJ10770, KIAA1579 ENSG00000162437 Ribonucleoprotein, PTB-binding 2 1 64745095-64833232 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045785 Approved Approved Nucleoplasm Mixed rectum: 29.9 -CTRC CLCR, ELA4 ENSG00000162438 Chymotrypsin C (caldecrin) 1 15438439-15449242 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046920 Supported Tissue enriched 360 pancreas: 18181.6 ovary: 50.5 -LZIC MGC15436 ENSG00000162441 Leucine zipper and CTNNBIP1 domain containing 1 9922113-9943407 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028184, HPA058614 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 119.4 -RBP7 CRBPIV ENSG00000162444 Retinol binding protein 7, cellular 1 9997206-10016020 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034749 Approved Uncertain Nuclear speckles
Cytosol Tissue enhanced 0 adipose tissue: 259.6 breast: 81.7 -KNCN FLJ32011, KINO, L5 ENSG00000162456 Kinocilin 1 46545644-46551527 Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA046357 Uncertain Not detected testis: 0.7 -FBLIM1 CAL, FBLP-1, migfilin ENSG00000162458 Filamin binding LIM protein 1 1 15756607-15786594 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025287, HPA072750 Approved Supported Nucleoli fibrillar center
Cell Junctions
Focal adhesion sites Mixed gallbladder: 102.3 -TMEM82 ENSG00000162460 Transmembrane protein 82 1 15742422-15747982 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA060282 Uncertain Tissue enhanced 0 duodenum: 23.7;liver: 9.0;small intestine: 19.8 kidney: 7.6 -SLC25A34 DKFZp781A10161 ENSG00000162461 Solute carrier family 25, member 34 1 15736405-15741396 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA069806 Supported Mitochondria Tissue enhanced 0 duodenum: 14.9;small intestine: 15.5 skeletal muscle: 8.2 -AKR7A3 ENSG00000162482 Aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1 19282558-19289250 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064638 Approved Cytosol Tissue enhanced 0 duodenum: 175.1;small intestine: 109.2 stomach: 69.3 -DRAXIN C1orf187, Draxin, FLJ34999, Neucrin ENSG00000162490 Dorsal inhibitory axon guidance protein 1 11691729-11725857 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014302 Uncertain Tissue enhanced 0 cerebral cortex: 1.5 testis: 0.6 -PDPN aggrus, Gp38, GP40, PA2.26, T1A-2 ENSG00000162493 Podoplanin 1 13583465-13617957 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007534, CAB008376, HPA073453 Supported Approved Vesicles Tissue enhanced 0 placenta: 192.4 appendix: 80.4 -LRRC38 ENSG00000162494 Leucine rich repeat containing 38 1 13474977-13514048 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038778 Approved Group enriched 19 adrenal gland: 20.0;skeletal muscle: 10.5 placenta: 0.8 -DHRS3 RDH17, retSDR1, Rsdr1, SDR1, SDR16C1 ENSG00000162496 Dehydrogenase/reductase (SDR family) member 3 1 12567910-12617731 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010844 Supported Approved Nucleoli
Mitochondria Expressed in all adipose tissue: 99.6 -MATN1 CMP, CRTM ENSG00000162510 Matrilin 1, cartilage matrix protein 1 30711277-30723587 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028580 Supported Not detected ovary: 0.9 -LAPTM5 ENSG00000162511 Lysosomal protein transmembrane 5 1 30732469-30757820 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051293 Approved Approved Cytosol Expressed in all bone marrow: 801.2 -SDC3 N-syndecan, SYND3 ENSG00000162512 Syndecan 3 1 30869467-30908761 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017087, CAB025786, HPA048085 Approved Approved Nucleoplasm
Mitochondria Expressed in all cerebral cortex: 136.8 -PEF1 PEF1A ENSG00000162517 Penta-EF-hand domain containing 1 1 31629862-31644896 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061608 Approved Nucleoplasm
Vesicles
Cytosol Expressed in all thyroid gland: 182.4 -SYNC SYNC1, SYNCOILIN ENSG00000162520 Syncoilin, intermediate filament protein 1 32680360-32703596 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028311 Approved Approved Golgi apparatus
Vesicles
Plasma membrane Tissue enhanced 0 smooth muscle: 70.4 skeletal muscle: 36.1 -RBBP4 lin-53, NURF55, RbAp48 ENSG00000162521 Retinoblastoma binding protein 4 1 32651142-32686211 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006264, HPA060710, HPA060724 Supported Validated Nucleoplasm Expressed in all testis: 138.1 -KIAA1522 ENSG00000162522 KIAA1522 1 32741885-32774970 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032050, HPA032051, HPA064839 Approved Supported Nucleoplasm
Plasma membrane
Cell Junctions Mixed skin: 73.0 -TSSK3 SPOGA3, STK22C ENSG00000162526 Testis-specific serine kinase 3 1 32351521-32364312 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA037516 Uncertain Approved Nucleus
Nucleoli
Nuclear bodies Tissue enhanced 0 testis: 25.2 parathyroid gland: 6.4 -TMCO4 DKFZp686C23231 ENSG00000162542 Transmembrane and coiled-coil domains 4 1 19682213-19799945 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014601, HPA014620 Uncertain Approved Endoplasmic reticulum Mixed parathyroid gland: 36.3 -UBXN10 FLJ25429, UBXD3 ENSG00000162543 UBX domain protein 10 1 20186085-20196048 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA028555, HPA028564 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cell Junctions Tissue enhanced 0 fallopian tube: 78.2 testis: 25.4 -CAMK2N1 CaMKIINalpha ENSG00000162545 Calcium/calmodulin-dependent protein kinase II inhibitor 1 1 20482391-20486220 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 322.1 small intestine: 97.5 -ALPL HOPS, TNSALP ENSG00000162551 Alkaline phosphatase, liver/bone/kidney 1 21509372-21578412 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007105, HPA008765, CAB020829 Approved Approved Cytosol Tissue enhanced 0 lung: 78.9 kidney: 47.0 -WNT4 WNT-4 ENSG00000162552 Wingless-type MMTV integration site family, member 4 1 22117305-22143969 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011397 Uncertain Approved Vesicles Tissue enhanced 0 skin: 49.2 ovary: 15.3 -TTLL10 FLJ36119, TTLL5 ENSG00000162571 Tubulin tyrosine ligase-like family member 10 1 1173884-1197935 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042712 Uncertain Group enriched 7 fallopian tube: 14.1;testis: 28.0 lung: 2.8 -SCNN1D dNaCh, ENaCdelta ENSG00000162572 Sodium channel, non voltage gated 1 delta subunit 1 1280436-1292029 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level CAB009540, HPA026884 Approved Supported Plasma membrane
Actin filaments Tissue enhanced 0 testis: 13.8 cerebral cortex: 7.3 -MXRA8 DKFZp586E2023 ENSG00000162576 Matrix-remodelling associated 8 1 1352689-1361777 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053958, HPA055780 Uncertain Approved Nucleoli Tissue enhanced 0 adipose tissue: 57.3 endometrium: 44.5 -FAAP20 C1orf86, FLJ31031 ENSG00000162585 Fanconi anemia core complex associated protein 20 1 2184461-2212720 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038829 Uncertain Supported Nucleoplasm
Nuclear bodies
Cell Junctions Expressed in all adipose tissue: 13.2 -MEGF6 EGFL3 ENSG00000162591 Multiple EGF-like-domains 6 1 3489920-3611495 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052129 Uncertain Approved Microtubules
Cytokinetic bridge Tissue enhanced 0 skin: 48.3 gallbladder: 17.1 -CCDC27 FLJ32825 ENSG00000162592 Coiled-coil domain containing 27 1 3752398-3771645 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 54 testis: 18.4 seminal vesicle: 0.3 -IL23R IL-23R ENSG00000162594 Interleukin 23 receptor 1 67166400-67259979 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056427 Uncertain Tissue enhanced 0 adrenal gland: 2.1;testis: 2.2 rectum: 0.9 -DIRAS3 ARHI, NOEY2 ENSG00000162595 DIRAS family, GTP-binding RAS-like 3 1 68045962-68051631 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028483, HPA028557, HPA029384 Approved Approved Nuclear membrane
Cytosol Tissue enhanced 0 ovary: 70.8 parathyroid gland: 24.8 -C1orf87 CREF, MGC34837 ENSG00000162598 Chromosome 1 open reading frame 87 1 59987269-60073770 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031366, HPA031368 Supported Tissue enriched 10 fallopian tube: 47.2 lung: 4.9 -NFIA KIAA1439, NFI-L ENSG00000162599 Nuclear factor I/A 1 60865259-61462793 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006111, HPA008884 Supported Validated Nucleoplasm Expressed in all thyroid gland: 53.5 -OMA1 FLJ33782, MPRP-1, YKR087C, ZMPOMA1 ENSG00000162600 OMA1 zinc metallopeptidase 1 58415384-58546802 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055120 Approved Approved Nucleoplasm
Mitochondria Expressed in all prostate: 32.2 -MYSM1 KIAA1915 ENSG00000162601 Myb-like, SWIRM and MPN domains 1 1 58654739-58700092 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054291, HPA067133 Approved Supported Nucleoplasm
Plasma membrane Mixed skin: 11.1 -TM2D1 BBP ENSG00000162604 TM2 domain containing 1 1 61681046-61725423 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046058, HPA055621 Approved Validated Nucleoplasm Expressed in all thyroid gland: 67.8 -USP1 ENSG00000162607 Ubiquitin specific peptidase 1 1 62436297-62451804 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028387, HPA028440 Approved Supported Nucleoplasm Expressed in all testis: 91.8 -FUBP1 FBP, FUBP ENSG00000162613 Far upstream element (FUSE) binding protein 1 1 77944055-77979110 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006149 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 68.1 -NEXN NELIN, nexilin ENSG00000162614 Nexilin (F actin binding protein) 1 77888513-77943895 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011185 Approved Tissue enhanced 0 heart muscle: 279.0;skeletal muscle: 249.0 smooth muscle: 108.3 -DNAJB4 HLJ1 ENSG00000162616 DnaJ (Hsp40) homolog, subfamily B, member 4 1 77979175-78017964 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004995, HPA028383, HPA028385 Approved Validated Nucleoplasm
Plasma membrane
Cytosol Expressed in all thyroid gland: 74.0 -ADGRL4 ELTD1, ETL ENSG00000162618 Adhesion G protein-coupled receptor L4 1 78889764-79006718 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA025229 Supported Mixed adipose tissue: 67.6 -LRRIQ3 LRRC44, MGC22773 ENSG00000162620 Leucine-rich repeats and IQ motif containing 3 1 74026015-74198187 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030799 Approved Supported Plasma membrane Tissue enriched 11 testis: 36.9 fallopian tube: 3.4 -LRRC53 ENSG00000162621 Leucine rich repeat containing 53 1 74469878-74512614 Predicted membrane proteins No evidence No evidence No evidence HPA054062 Uncertain Not detected cerebral cortex: 0.5 -TYW3 C1orf171, FLJ40918 ENSG00000162623 TRNA-yW synthesizing protein 3 homolog (S. cerevisiae) 1 74733152-74766678 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029641 Approved Approved Plasma membrane
Cytosol Expressed in all ovary: 32.6 -LHX8 Lhx7 ENSG00000162624 LIM homeobox 8 1 75128434-75161533 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA071806 Approved Nucleus
Nucleoli
Cytosol Tissue enhanced 0 placenta: 1.8;testis: 1.4;tonsil: 1.6 urinary bladder: 1.0 -SNX7 ENSG00000162627 Sorting nexin 7 1 98661701-98760500 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037419, HPA054338 Approved Approved Nucleoli fibrillar center
Cytosol Mixed smooth muscle: 37.6 -B3GALT2 beta3Gal-T2 ENSG00000162630 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 1 193179045-193186654 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA078659 Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 29.0;gallbladder: 26.0 heart muscle: 16.2 -NTNG1 KIAA0976, Lmnt1 ENSG00000162631 Netrin G1 1 107140007-107483458 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065954 Supported Plasma membrane Tissue enhanced 0 cerebral cortex: 8.6 seminal vesicle: 6.6 -FAM102B DKFZp779B126, SYM-3B ENSG00000162636 Family with sequence similarity 102, member B 1 108560089-108644900 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028451 Uncertain Approved Nucleoli
Cytosol Mixed cerebral cortex: 28.0 -HENMT1 C1orf59, FLJ30525, HEN1 ENSG00000162639 HEN1 methyltransferase homolog 1 (Arabidopsis) 1 108648290-108661526 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028464, HPA028497 Uncertain Approved Plasma membrane
Focal adhesion sites Tissue enriched 8 testis: 127.7 lymph node: 15.0 -AKNAD1 C1orf62, MGC26989 ENSG00000162641 AKNA domain containing 1 1 108815898-108858228 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030270, HPA030271, HPA030272 Uncertain Tissue enriched 41 testis: 4.2 skin: 0.1 -C1orf52 FLJ44982, gm117 ENSG00000162642 Chromosome 1 open reading frame 52 1 85249953-85259672 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036072, HPA061790 Approved Validated Nucleus Expressed in all cerebral cortex: 31.9 -WDR63 DIC3, FLJ30067, NYD-SP29 ENSG00000162643 WD repeat domain 63 1 84999147-85133138 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038526 Supported Tissue enhanced 0 adrenal gland: 28.4;fallopian tube: 22.8;testis: 33.4 parathyroid gland: 6.1 -GBP2 ENSG00000162645 Guanylate binding protein 2, interferon-inducible 1 89106132-89150456 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042682, CAB045975 Supported Supported Nucleoplasm
Actin filaments
Cytosol Expressed in all parathyroid gland: 192.3 -ATXN7L2 FLJ00381, MGC46534 ENSG00000162650 Ataxin 7-like 2 1 109483479-109492804 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA029827, HPA054952 Uncertain Approved Nucleoli
Vesicles
Cytosol Mixed testis: 4.3 -GBP4 Mpa2 ENSG00000162654 Guanylate binding protein 4 1 89181148-89198932 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030101, HPA062039 Approved Uncertain Plasma membrane Mixed lung: 47.2 -ZNF326 FLJ20403, ZAN75, Zfp326, ZIRD ENSG00000162664 Zinc finger protein 326 1 89995112-90035531 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028450, HPA028461, HPA028466 Supported Validated Nucleoplasm
Golgi apparatus
Vesicles Expressed in all bone marrow: 29.5 -HFM1 FLJ36760, FLJ39011, MER3, SEC63D1 ENSG00000162669 HFM1, ATP-dependent DNA helicase homolog 1 91260766-91404869 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035036, HPA035557 Uncertain Golgi apparatus
Vesicles Tissue enriched 5 testis: 24.9 ovary: 4.7 -BRINP3 DBCCR1L, DBCCR1L1, FAM5C ENSG00000162670 Bone morphogenetic protein/retinoic acid inducible neural-specific 3 1 190097662-190478404 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054693 Uncertain Tissue enhanced 0 cerebral cortex: 44.6;small intestine: 20.0 prostate: 10.5 -GFI1 GFI-1, GFI1A, ZNF163 ENSG00000162676 Growth factor independent 1 transcription repressor 1 92474762-92486876 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level CAB011197 Uncertain Tissue enhanced 0 bone marrow: 34.9 lymph node: 8.2 -KCNT2 KCa4.2, SLICK, SLO2.1 ENSG00000162687 Potassium channel, sodium activated subfamily T, member 2 1 196225779-196609225 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051218 Uncertain Approved Vesicles Tissue enhanced 0 ovary: 6.0 cerebral cortex: 3.5 -AGL ENSG00000162688 Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 1 99850084-99924023 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028498, HPA054340 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 skeletal muscle: 91.0 parathyroid gland: 34.5 -VCAM1 CD106 ENSG00000162692 Vascular cell adhesion molecule 1 1 100719742-100739045 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000154, HPA034796, HPA069867 Supported Approved Cell Junctions Tissue enriched 5 spleen: 557.0 lymph node: 111.2 -EXTL2 ENSG00000162694 Exostosin-like glycosyltransferase 2 1 100872372-100895998 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB020716, HPA068921 Approved Approved Nucleus
Cytosol Expressed in all placenta: 33.9 -SLC30A7 ZNT7, ZnTL2 ENSG00000162695 Solute carrier family 30 (zinc transporter), member 7 1 100896076-100981753 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA018034 Uncertain Supported Golgi apparatus Mixed parathyroid gland: 20.6 -ZNF281 ZBP-99 ENSG00000162702 Zinc finger protein 281 1 200404940-200410056 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051228 Uncertain Validated Nucleoplasm Expressed in all bone marrow: 21.5 -ARPC5 ARC16, dJ127C7.3, p16-Arc ENSG00000162704 Actin related protein 2/3 complex, subunit 5, 16kDa 1 183620846-183635757 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022013, HPA031972 Approved Approved Vesicles
Plasma membrane
Cell Junctions
Cytosol Expressed in all appendix: 207.6 -CADM3 BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1 ENSG00000162706 Cell adhesion molecule 3 1 159171609-159203313 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002981, CAB025746 Supported Tissue enhanced 0 cerebral cortex: 279.4;placenta: 113.9 cervix: 48.6 -NLRP3 AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCU, MWS, NALP3, PYPAF1 ENSG00000162711 NLR family, pyrin domain containing 3 1 247416156-247449108 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA012878 Uncertain Tissue enhanced 0 bone marrow: 34.5 appendix: 14.9 -ZNF496 MGC15548, ZKSCAN17, ZSCAN49 ENSG00000162714 Zinc finger protein 496 1 247297412-247331846 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055834 Uncertain Golgi apparatus Expressed in all fallopian tube: 23.9 -TRIM58 BIA2 ENSG00000162722 Tripartite motif containing 58 1 247857199-247878205 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023637 Uncertain Group enriched 6 bone marrow: 16.2;placenta: 6.8;testis: 6.6;thyroid gland: 21.9 prostate: 2.0 -SLAMF9 CD2F-10, CD84-H1, SF2001 ENSG00000162723 SLAM family member 9 1 159951492-159954254 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035153 Uncertain Tissue enhanced 0 testis: 1.3 appendix: 0.6 -OR2M5 OR2M5P ENSG00000162727 Olfactory receptor, family 2, subfamily M, member 5 1 248145148-248146086 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -KCNJ9 GIRK3, Kir3.3 ENSG00000162728 Potassium channel, inwardly rectifying subfamily J, member 9 1 160081570-160090563 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA070478 Supported Tissue enriched 112 cerebral cortex: 52.5 testis: 0.4 -IGSF8 CD316, CD81P3, EWI2, PGRL ENSG00000162729 Immunoglobulin superfamily, member 8 1 160091340-160098943 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011917 Uncertain Expressed in all cerebral cortex: 108.1 -DDR2 NTRKR3, TKT, TYRO10 ENSG00000162733 Discoidin domain receptor tyrosine kinase 2 1 162631373-162787400 CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070112 Supported Plasma membrane
Actin filaments Mixed adrenal gland: 94.0 -PEA15 HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED ENSG00000162734 Phosphoprotein enriched in astrocytes 15 1 160205337-160215376 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028356 Approved Nucleus
Cytosol Expressed in all cerebral cortex: 1090.0 -PEX19 D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1 ENSG00000162735 Peroxisomal biogenesis factor 19 1 160276812-160286348 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044837, HPA051966 Supported Validated Peroxisomes Expressed in all adipose tissue: 85.8 -NCSTN APH2, KIAA0253 ENSG00000162736 Nicastrin 1 160343272-160358952 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB021982, HPA054846, HPA070642 Approved Approved Cytosol Expressed in all parathyroid gland: 140.4 -VANGL2 KIAA1215, LPP1, LTAP, MGC119403, MGC119404, STB1, STBM, STBM1 ENSG00000162738 VANGL planar cell polarity protein 2 1 160400586-160428678 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027043 Uncertain Tissue enhanced 0 skin: 44.8 cerebral cortex: 18.2 -SLAMF6 CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000 ENSG00000162739 SLAM family member 6 1 160485030-160523262 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051363, HPA051903 Uncertain Tissue enhanced 0 lymph node: 71.8;spleen: 44.1;tonsil: 46.5 appendix: 28.3 -OLFML2B DKFZP586L151 ENSG00000162745 Olfactomedin-like 2B 1 161983192-162023854 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA054136, HPA062739 Approved Approved Cytosol Tissue enhanced 0 gallbladder: 77.2 placenta: 58.1 -FCRLB FCRL2, FCRLM2, FCRLY, FLJ31052, FREB-2 ENSG00000162746 Fc receptor-like B 1 161721563-161728143 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB026139 Uncertain Supported Cytosol Tissue enhanced 0 tonsil: 1.7 seminal vesicle: 1.3 -FCGR3B CD16, CD16b, FCG3, FCGR3 ENSG00000162747 Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1 161623196-161631963 CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 120.2;spleen: 116.8 urinary bladder: 37.8 -SLC9C2 MGC43026, SLC9A11 ENSG00000162753 Solute carrier family 9, member C2 (putative) 1 173500464-173603094 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12 testis: 10.6 fallopian tube: 0.8 -KLHDC9 KARCA1 ENSG00000162755 Kelch domain containing 9 1 161098361-161100346 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA032058, HPA043197 Uncertain Uncertain Nucleoplasm Tissue enhanced 0 testis: 9.5 fallopian tube: 2.3 -C1orf74 FLJ25078 ENSG00000162757 Chromosome 1 open reading frame 74 1 209779208-209784559 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA028496 Uncertain Approved Plasma membrane
Cytosol Mixed lymph node: 5.1 -LMX1A LMX1, LMX1.1 ENSG00000162761 LIM homeobox transcription factor 1, alpha 1 165201867-165356715 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA028051, HPA030088 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Tissue enhanced 0 duodenum: 1.1;testis: 2.4 adipose tissue: 0.6 -LRRC52 FLJ25811 ENSG00000162763 Leucine rich repeat containing 52 1 165544007-165563961 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 27 testis: 18.5 parathyroid gland: 0.6 -FLVCR1 AXPC1, FLVCR, MFSD7B, PCA ENSG00000162769 Feline leukemia virus subgroup C cellular receptor 1 1 212858255-212899363 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046646 Approved Approved Cell Junctions Tissue enhanced 0 small intestine: 21.9 duodenum: 10.0 -FAM71A FLJ32796 ENSG00000162771 Family with sequence similarity 71, member A 1 212624474-212626778 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028462 Supported Tissue enriched 96 testis: 78.7 fallopian tube: 0.8 -ATF3 ENSG00000162772 Activating transcription factor 3 1 212565334-212620777 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001562 Approved Validated Nucleus
Nucleoli Expressed in all smooth muscle: 445.6 -RBM15 OTT, OTT1 ENSG00000162775 RNA binding motif protein 15 1 110338506-110346681 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015201, HPA019824, HPA049642 Supported Validated Nucleoplasm Mixed bone marrow: 27.9 -DENND2D FLJ22457, RP5-1180E21.2 ENSG00000162777 DENN/MADD domain containing 2D 1 111187174-111204535 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043630, HPA048642 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 lymph node: 112.2 tonsil: 80.0 -AXDND1 C1orf125, FLJ32940 ENSG00000162779 Axonemal dynein light chain domain containing 1 1 179365720-179554735 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA071114 Supported Tissue enriched 52 testis: 24.4 epididymis: 0.4 -TDRD5 FLJ34823, TUDOR3 ENSG00000162782 Tudor domain containing 5 1 179591613-179691272 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029418 Supported Tissue enriched 5 testis: 42.4 epididymis: 7.8 -IER5 ENSG00000162783 Immediate early response 5 1 181088712-181092899 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029894 Uncertain Approved Supported Nucleus
Nucleoli Mixed bone marrow: 31.2 -SNED1 FLJ00133, Snep, SST3 ENSG00000162804 Sushi, nidogen and EGF-like domains 1 2 240998838-241095568 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036414, HPA036415 Uncertain Mixed endometrium: 30.0 -BPNT1 ENSG00000162813 3'(2'), 5'-bisphosphate nucleotidase 1 1 220057482-220090462 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048461 Approved Approved Nuclear speckles Expressed in all small intestine: 49.6 -SPATA17 IQCH ENSG00000162814 Spermatogenesis associated 17 1 217631324-217871696 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030099 Approved Approved Nucleus
Nucleoli Tissue enhanced 0 testis: 18.1 fallopian tube: 6.5 -C1orf115 FLJ14146 ENSG00000162817 Chromosome 1 open reading frame 115 1 220689845-220699157 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed small intestine: 113.1 -BROX C1orf58, FLJ32421 ENSG00000162819 BRO1 domain and CAAX motif containing 1 222712553-222735196 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031445 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all parathyroid gland: 46.0 -NBPF20 ENSG00000162825 Neuroblastoma breakpoint family, member 20 1 145289900-145405778 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Uncertain Approved Vesicles Mixed parathyroid gland: 16.3 -ACP6 ACPL1, LPAP ENSG00000162836 Acid phosphatase 6, lysophosphatidic 1 147629652-147670496 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028560 Uncertain Expressed in all parathyroid gland: 26.5 -WDR64 FLJ32978 ENSG00000162843 WD repeat domain 64 1 241652278-241802133 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046186 Uncertain Tissue enriched 10 testis: 5.5 placenta: 0.5 -KIF26B FLJ10157 ENSG00000162849 Kinesin family member 26B 1 245154985-245709431 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027709, HPA028478, HPA028561, HPA028562 Approved Approved Plasma membrane
Microtubules Mixed cerebral cortex: 2.3 -TFB2M FLJ22661, FLJ23182, Hkp1 ENSG00000162851 Transcription factor B2, mitochondrial 1 246540560-246566324 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028482, HPA030265, HPA061095 Approved Validated Mitochondria Expressed in all adrenal gland: 29.7 -CNST C1orf71, FLJ32001, PPP1R64 ENSG00000162852 Consortin, connexin sorting protein 1 246566444-246668584 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007225, HPA007226 Approved Supported Vesicles Expressed in all cerebral cortex: 26.4 -PPP1R21 CCDC128, FLJ16566, KLRAQ1 ENSG00000162869 Protein phosphatase 1, regulatory subunit 21 2 48440598-48515391 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036791, HPA036792 Approved Approved Vesicles Expressed in all parathyroid gland: 61.0 -KLHDC8A FLJ10748 ENSG00000162873 Kelch domain containing 8A 1 205336065-205357090 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 11 ovary: 287.7 adrenal gland: 26.1 -PM20D1 Cps1, FLJ32569 ENSG00000162877 Peptidase M20 domain containing 1 1 205828022-205850132 Enzymes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 kidney: 5.9;pancreas: 16.6 skin: 3.9 -PKDCC SgK493, Vlk ENSG00000162878 Protein kinase domain containing, cytoplasmic 2 42048020-42058528 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA026427, HPA026442, HPA026526 Uncertain Mixed adipose tissue: 27.4 -OXER1 GPCR, GPR170, TG1019 ENSG00000162881 Oxoeicosanoid (OXE) receptor 1 2 42762481-42764261 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051433 Uncertain Mixed small intestine: 9.3 -HAAO ENSG00000162882 3-hydroxyanthranilate 3,4-dioxygenase 2 42767089-42792593 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036394, HPA042024 Supported Tissue enhanced 0 liver: 151.8 small intestine: 46.4 -B3GALNT2 MGC39558 ENSG00000162885 Beta-1,3-N-acetylgalactosaminyltransferase 2 1 235449923-235504481 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012502, HPA050662 Approved Approved Nucleoplasm
Golgi apparatus Mixed smooth muscle: 15.7 -MAPKAPK2 ENSG00000162889 Mitogen-activated protein kinase-activated protein kinase 2 1 206684944-206734283 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010297, HPA045556, HPA063708, HPA064435 Approved Supported Nucleoplasm
Centrosome Expressed in all bone marrow: 113.2 -IL20 IL-20, IL10D, ZCYTO10 ENSG00000162891 Interleukin 20 1 206865354-206869223 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB025802 Uncertain Tissue enhanced 0 smooth muscle: 1.0 seminal vesicle: 0.8 -IL24 C49A, FISP, IL-24, IL10B, mda-7, Mob-5, ST16 ENSG00000162892 Interleukin 24 1 206897443-206904139 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB025972 Uncertain Group enriched 5 appendix: 17.9;lymph node: 37.6;spleen: 30.0;tonsil: 28.5 urinary bladder: 5.6 -FCMR FAIM3, TOSO ENSG00000162894 Fc fragment of IgM receptor 1 206904386-206923247 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003910 Approved Approved Nucleus
Focal adhesion sites
Cytosol Tissue enhanced 0 lymph node: 178.0;spleen: 150.5;tonsil: 152.4 appendix: 91.5 -PIGR ENSG00000162896 Polymeric immunoglobulin receptor 1 206928518-206946466 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006154, CAB009454, HPA012012 Supported Uncertain Nucleus
Nucleoli
Cytosol Tissue enhanced 0 colon: 1721.7;duodenum: 2732.8 rectum: 1357.3 -FCAMR CD351, FCA/MR, FKSG87 ENSG00000162897 Fc receptor, IgA, IgM, high affinity 1 206957965-206970625 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 kidney: 32.0;lymph node: 14.1;tonsil: 11.7 appendix: 5.4 -CAPN2 CANPL2, CANPml, mCANP ENSG00000162909 Calpain 2, (m/II) large subunit 1 223701593-223776018 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024470 Approved Supported Cytosol Expressed in all lung: 267.2 -MRPL55 ENSG00000162910 Mitochondrial ribosomal protein L55 1 228106679-228109312 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027641 Approved Expressed in all cerebral cortex: 41.0 -C1orf145 FLJ31994 ENSG00000162913 Chromosome 1 open reading frame 145 1 228203506-228213664 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA046612 Uncertain Mixed thyroid gland: 1.1 -WDR26 FLJ21016, GID7 ENSG00000162923 WD repeat domain 26 1 224385143-224437033 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028539, HPA061094 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 53.8 -REL c-Rel, I-Rel ENSG00000162924 V-rel avian reticuloendotheliosis viral oncogene homolog 2 60881521-60931610 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004404 Uncertain Mixed bone marrow: 29.9 -PUS10 CCDC139, FLJ32312 ENSG00000162927 Pseudouridylate synthase 10 2 60940222-61018259 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044736, HPA049582 Approved Approved Nucleoplasm
Nuclear bodies
Mitochondria Mixed thyroid gland: 10.2 -PEX13 ENSG00000162928 Peroxisomal biogenesis factor 13 2 61017225-61051990 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032141, HPA032142, CAB032689 Supported Supported Vesicles Expressed in all testis: 27.4 -KIAA1841 ENSG00000162929 KIAA1841 2 61065871-61138034 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051240 Approved Approved Nucleus
Nucleoli Mixed prostate: 6.9 -TRIM17 RBCC, RNF16, terf ENSG00000162931 Tripartite motif containing 17 1 228407940-228416861 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054908 Uncertain Approved Vesicles Tissue enhanced 0 testis: 27.9 cerebral cortex: 6.1 -RFTN2 C2orf11, FLJ30574, Raftlin-2 ENSG00000162944 Raftlin family member 2 2 197568224-197676045 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035232 Approved Tissue enhanced 0 cerebral cortex: 31.5 ovary: 8.7 -DISC1 ENSG00000162946 Disrupted in schizophrenia 1 1 231626815-232041272 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013016 Uncertain Mixed placenta: 10.5 -CAPN13 FLJ23523 ENSG00000162949 Calpain 13 2 30722771-30820542 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029496, HPA029497, HPA030034 Uncertain Approved Nucleoplasm Tissue enhanced 0 rectum: 27.2;small intestine: 33.1;stomach: 26.3 duodenum: 21.4 -LRRTM1 FLJ32082 ENSG00000162951 Leucine rich repeat transmembrane neuronal 1 2 80288351-80304749 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062660 Approved Tissue enhanced 0 cerebral cortex: 13.3;salivary gland: 4.9 thyroid gland: 2.2 -MEMO1 C2orf4, CGI-27, MEMO ENSG00000162959 Mediator of cell motility 1 2 31865060-32011230 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042603, HPA057952 Approved Approved Vesicles Expressed in all testis: 117.5 -DPY30 Cps25, HDPY-30, Saf19 ENSG00000162961 Dpy-30 histone methyltransferase complex regulatory subunit 2 31867809-32039812 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043761 Supported Validated Nucleoplasm
Golgi apparatus Expressed in all fallopian tube: 136.5 -TYW5 C2orf60, FLJ37953 ENSG00000162971 TRNA-yW synthesizing protein 5 2 199929975-199955736 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028294, HPA045803 Uncertain Approved Nuclear bodies Mixed appendix: 1.6 -C2orf47 DKFZp666A212, FLJ22555 ENSG00000162972 Chromosome 2 open reading frame 47 2 199955317-200008540 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064013 Approved Mitochondria Expressed in all kidney: 31.7 -KCNF1 IK8, KCNF, kH1, Kv5.1 ENSG00000162975 Potassium channel, voltage gated modifier subfamily F, member 1 2 10911937-10914225 Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level CAB004678, HPA014738 Supported Approved Golgi apparatus Tissue enriched 32 cerebral cortex: 37.6 endometrium: 1.1 -PQLC3 C2orf22, MGC33602 ENSG00000162976 PQ loop repeat containing 3 2 11155198-11178874 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA061607 Approved Cytosol Expressed in all cervix: 54.2 -ARL5A ARL5 ENSG00000162980 ADP-ribosylation factor-like 5A 2 151788984-151828492 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027002 Approved Expressed in all thyroid gland: 64.4 -FAM84A FLJ35392, NSE1 ENSG00000162981 Family with sequence similarity 84, member A 2 14632686-14650814 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047703 Uncertain Approved Nucleus Mixed colon: 41.1 -KCNJ3 GIRK1, KGA, Kir3.1 ENSG00000162989 Potassium channel, inwardly rectifying subfamily J, member 3 2 154698299-154858352 Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024231 Uncertain Tissue enhanced 0 cerebral cortex: 25.5;parathyroid gland: 39.5 seminal vesicle: 14.1 -NEUROD1 BETA2, BHF-1, bHLHa3, MODY6, NEUROD ENSG00000162992 Neuronal differentiation 1 2 181673088-181680876 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA003278, CAB022450 Approved Tissue enhanced 0 cerebral cortex: 6.0;duodenum: 6.2;small intestine: 4.5;stomach: 4.9 pancreas: 1.8 -CLHC1 C2orf63, FLJ31438 ENSG00000162994 Clathrin heavy chain linker domain containing 1 2 55174791-55232563 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045418, HPA053557 Uncertain Approved Nucleoli fibrillar center
Centrosome Tissue enhanced 0 testis: 23.0 parathyroid gland: 7.8 -FRZB FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3 ENSG00000162998 Frizzled-related protein 2 182833275-182867162 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 spleen: 102.8 gallbladder: 50.5 -DUSP19 DUSP17, SKRP1 ENSG00000162999 Dual specificity phosphatase 19 2 183078559-183100005 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021501 Approved Approved Nucleoplasm Mixed testis: 7.0 -CFAP36 CCDC104, MGC15407 ENSG00000163001 Cilia and flagella associated protein 36 2 55519604-55545879 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008994, HPA017061 Approved Expressed in all testis: 237.8 -NUP35 MP44 ENSG00000163002 Nucleoporin 35kDa 2 183117513-183161680 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018401, HPA018410, HPA018441 Supported Supported Nucleoplasm
Nuclear membrane
Plasma membrane Expressed in all testis: 44.7 -CCDC138 FLJ32745 ENSG00000163006 Coiled-coil domain containing 138 2 108786757-108885477 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049899, HPA054223 Approved Approved Nucleus
Cytosol Tissue enhanced 0 testis: 19.5 fallopian tube: 6.8 -ZSWIM2 MGC33890, ZZZ2 ENSG00000163012 Zinc finger, SWIM-type containing 2 2 186827835-186849208 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 132 testis: 18.3 placenta: 0.1 -FBXO41 Fbx41, KIAA1940 ENSG00000163013 F-box protein 41 2 73254682-73284431 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055246, HPA058386 Approved Nucleus
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 38.4 parathyroid gland: 11.0 -ACTG2 ACTA3, ACTL3, ACTSG ENSG00000163017 Actin, gamma 2, smooth muscle, enteric 2 73892314-73919865 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041264, HPA041271 Supported Tissue enhanced 0 seminal vesicle: 8064.0;smooth muscle: 11485.7 prostate: 3363.6 -C2orf44 FLJ21945 ENSG00000163026 Chromosome 2 open reading frame 44 2 24029340-24049575 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041054 Approved Approved Nucleoli
Cytosol Mixed testis: 9.2 -SMC6 FLJ22116, SMC6L1 ENSG00000163029 Structural maintenance of chromosomes 6 2 17663812-17800242 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035057, CAB037186, HPA042733 Uncertain Supported Nucleoplasm Expressed in all testis: 64.5 -VSNL1 HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1 ENSG00000163032 Visinin-like 1 2 17539126-17657018 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053808 Approved Cytosol Tissue enriched 14 cerebral cortex: 625.9 esophagus: 44.2 -CCDC74A FLJ40345 ENSG00000163040 Coiled-coil domain containing 74A 2 131527675-131533666 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060727 Uncertain Vesicles Tissue enhanced 0 fallopian tube: 54.5;testis: 79.2 parathyroid gland: 26.7 -H3F3A H3.3A, H3F3 ENSG00000163041 H3 histone, family 3A 1 226061851-226072001 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB011481, CAB037178, HPA042570 Supported Supported Nucleoplasm Expressed in all bone marrow: 1218.1 -ANKRD30BL ANKRD30BP3, NCRNA00164 ENSG00000163046 Ankyrin repeat domain 30B-like 2 132147591-132257969 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 30 testis: 3.0 appendix: 0.1 -ADCK3 CABC1, COQ8, SCAR9 ENSG00000163050 AarF domain containing kinase 3 1 226897536-226987545 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061662 Supported Mitochondria Tissue enriched 6 skeletal muscle: 401.9 adrenal gland: 68.5 -SLC16A14 FLJ30794, MCT14 ENSG00000163053 Solute carrier family 16, member 14 2 230034974-230068999 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA040518 Uncertain Approved Cytosol Mixed parathyroid gland: 14.6 -TEKT4 MGC27019 ENSG00000163060 Tektin 4 2 94871433-94876829 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048600, HPA053929 Uncertain Uncertain Intermediate filaments Group enriched 15 fallopian tube: 4.2;testis: 5.2 lung: 0.3 -EN1 ENSG00000163064 Engrailed homeobox 1 2 118842171-118847678 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level No evidence CAB014884, HPA073141 Approved Supported Nucleus
Nucleoli Group enriched 13 adipose tissue: 1.3;breast: 1.0;lymph node: 1.9;skeletal muscle: 4.7;skin: 2.2 testis: 0.1 -SGCB A3b, LGMD2E, SGC ENSG00000163069 Sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 4 52020706-52038482 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011422, HPA058656 Supported Approved Cytosol Mixed parathyroid gland: 74.2 -SPATA18 FLJ32906 ENSG00000163071 Spermatogenesis associated 18 4 52051331-52097292 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036854, HPA036855 Supported Tissue enhanced 0 fallopian tube: 108.1;testis: 42.4 cervix: 16.1 -NOSTRIN MGC20702 ENSG00000163072 Nitric oxide synthase trafficking 2 168786539-168865514 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044384 Approved Mixed placenta: 36.0 -CFAP221 FAP221, PCDP1 ENSG00000163075 Cilia and flagella associated protein 221 2 119544432-119662251 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 fallopian tube: 41.6;testis: 44.6 lung: 11.6 -CCDC140 FLJ32447 ENSG00000163081 Coiled-coil domain containing 140 2 222298147-222305217 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA042500, HPA048166 Uncertain Not detected skin: 0.3 -SGPP2 FLJ39004, SPP2 ENSG00000163082 Sphingosine-1-phosphate phosphatase 2 2 222424517-222560948 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 parathyroid gland: 58.4 thyroid gland: 33.8 -INHBB ENSG00000163083 Inhibin, beta B 2 120346143-120351808 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049218 Uncertain Nucleoplasm Tissue enhanced 0 testis: 27.1 adipose tissue: 24.8 -XIRP2 CMYA3 ENSG00000163092 Xin actin binding repeat containing 2 2 166888487-167259753 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034813 Uncertain Group enriched 26 heart muscle: 68.8;skeletal muscle: 301.7 prostate: 7.2 -BBS5 DKFZp762I194 ENSG00000163093 Bardet-Biedl syndrome 5 2 169479178-169506655 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046125 Uncertain Mixed testis: 12.8 -BIRC8 hILP2, ILP-2 ENSG00000163098 Baculoviral IAP repeat containing 8 19 53289601-53291626 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 178 testis: 17.7 epididymis: 0.0 -SMARCAD1 DKFZP762K2015, ETL1, KIAA1122 ENSG00000163104 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 4 94207611-94291292 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016737 Approved Validated Nucleoplasm Expressed in all thyroid gland: 25.5 -HPGDS GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS ENSG00000163106 Hematopoietic prostaglandin D synthase 4 94298535-94342876 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024035 Supported Tissue enhanced 0 placenta: 28.0 lung: 14.5 -PDLIM5 Enh, LIM ENSG00000163110 PDZ and LIM domain 5 4 94451857-94668227 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013511, HPA016740, HPA020026 Approved Supported Nucleoplasm
Plasma membrane
Focal adhesion sites Expressed in all skeletal muscle: 407.0 -PDHA2 PDHAL ENSG00000163114 Pyruvate dehydrogenase (lipoamide) alpha 2 4 95840019-95841474 Citric acid cycle related proteins, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047487, HPA047864, HPA063053 Approved Supported Mitochondria Tissue enriched 1006 testis: 100.5 epididymis: 0.0 -STPG2 C4orf37, MGC46496 ENSG00000163116 Sperm-tail PG-rich repeat containing 2 4 97184093-98143240 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 3.9 thyroid gland: 0.9 -NEURL3 Lincr, LOC93082 ENSG00000163121 Neuralized E3 ubiquitin protein ligase 3 2 96497643-96508109 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 salivary gland: 13.9 pancreas: 4.2 -RPRD2 FLJ32145, HSPC099, KIAA0460 ENSG00000163125 Regulation of nuclear pre-mRNA domain containing 2 1 150363091-150476566 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061693 Approved Nucleoplasm
Vesicles Expressed in all thyroid gland: 38.2 -ANKRD23 DARP, FLJ32449, MARP3 ENSG00000163126 Ankyrin repeat domain 23 2 96824526-96857934 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA036201 Approved Supported Nucleoplasm
Actin filaments Tissue enriched 71 skeletal muscle: 495.7 heart muscle: 6.9 -CTSS ENSG00000163131 Cathepsin S 1 150730196-150765957 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000460, HPA002988 Supported Approved Vesicles Expressed in all spleen: 381.4 -MSX1 HOX7, HYD1, OFC5 ENSG00000163132 Msh homeobox 1 4 4859666-4863936 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB026198, HPA063895, HPA073604 Supported Supported Nucleoplasm Group enriched 6 cervix, uterine: 60.9;endometrium: 23.8 adipose tissue: 6.7 -PACRGL C4orf28, MGC29898 ENSG00000163138 PARK2 co-regulated-like 4 20696282-20752907 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054666 Approved Nucleoplasm
Vesicles Expressed in all testis: 59.8 -BNIPL BNIPl-1, BNIPL-2, PP753 ENSG00000163141 BCL2/adenovirus E1B 19kD interacting protein like 1 151036570-151047600 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 7 esophagus: 89.3;skin: 227.3 breast: 21.8 -C1QTNF7 CTRP7 ENSG00000163145 C1q and tumor necrosis factor related protein 7 4 15339818-15446166 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB007055, HPA051797 Uncertain Mixed cervix: 36.3 -TNFAIP8L2 FLJ23467 ENSG00000163154 Tumor necrosis factor, alpha-induced protein 8-like 2 1 151156629-151159749 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062742 Uncertain Vesicles Tissue enhanced 0 lymph node: 35.2;spleen: 39.7 appendix: 26.6 -LYSMD1 MGC35223, RP11-68I18.5, SB145 ENSG00000163155 LysM, putative peptidoglycan-binding, domain containing 1 1 151159748-151165948 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028055, HPA064537 Uncertain Validated Nucleus Mixed ovary: 13.2 -SCNM1 MGC3180 ENSG00000163156 Sodium channel modifier 1 1 151156664-151170297 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052439, HPA054324 Uncertain Approved Nucleus Expressed in all lymph node: 45.9 -TMOD4 Sk-Tmod ENSG00000163157 Tropomodulin 4 (muscle) 1 151169986-151176284 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028203 Supported Tissue enriched 30 skeletal muscle: 378.9 esophagus: 12.6 -VPS72 Swc2, TCFL1, YL-1, YL1 ENSG00000163159 Vacuolar protein sorting 72 homolog (S. cerevisiae) 1 151169987-151195321 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065709 Supported Nuclear speckles Expressed in all cerebral cortex: 30.9 -ERCC3 BTF2, GTF2H, RAD25, TFIIH, XPB ENSG00000163161 Excision repair cross-complementation group 3 2 127257290-127294176 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037153, HPA046077 Approved Validated Nucleoplasm Expressed in all testis: 54.8 -RNF149 FLJ90504 ENSG00000163162 Ring finger protein 149 2 101271219-101308701 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA011424 Approved Approved Vesicles
Plasma membrane Expressed in all appendix: 69.4 -IWS1 DKFZp761G0123, FLJ10006, FLJ14655, FLJ32319 ENSG00000163166 IWS1 homolog (S. cerevisiae) 2 127436207-127526886 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035719, HPA061866 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 43.4 -BOLA3 ENSG00000163170 BolA family member 3 2 74135398-74147994 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053162 Uncertain Expressed in all heart muscle: 52.3 -CDC42EP3 BORG2, CEP3, UB1 ENSG00000163171 CDC42 effector protein (Rho GTPase binding) 3 2 37641882-37738468 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034986 Approved Approved Nucleoli
Cytosol Expressed in all endometrium: 150.3 -S100A11 S100C ENSG00000163191 S100 calcium binding protein A11 1 152032506-152047907 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034320, HPA042745 Supported Expressed in all esophagus: 2733.4 -LCE3D LEP16, SPRL6A, SPRL6B ENSG00000163202 Late cornified envelope 3D 1 152579381-152580504 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 26.5;tonsil: 83.1 esophagus: 11.7 -SMCP MCSP ENSG00000163206 Sperm mitochondria-associated cysteine-rich protein 1 152878317-152885047 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035105 Supported Tissue enriched 476 testis: 792.8 cerebral cortex: 1.6 -IVL ENSG00000163207 Involucrin 1 152908545-152911886 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002243, HPA055211 Supported Supported Nuclear bodies
Centrosome
Cytosol Group enriched 6 esophagus: 309.5;skin: 131.5 tonsil: 34.2 -SPRR3 ENSG00000163209 Small proline-rich protein 3 1 153001747-153003856 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044467 Supported Tissue enriched 10 esophagus: 22163.5 tonsil: 2312.3 -DHX57 DDX57 ENSG00000163214 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 2 38797729-38875934 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036160 Uncertain Approved Nucleoli
Intermediate filaments
Microtubules
Cytosol Mixed testis: 30.7 -SPRR2D ENSG00000163216 Small proline-rich protein 2D 1 153039725-153041931 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 6 esophagus: 2283.1 tonsil: 361.4 -BMP10 ENSG00000163217 Bone morphogenetic protein 10 2 68865481-68871517 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 171 heart muscle: 612.5 liver: 3.5 -PGLYRP4 PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67 ENSG00000163218 Peptidoglycan recognition protein 4 1 153330120-153348840 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB025879 Approved Vesicles
Plasma membrane Group enriched 5 esophagus: 5.8;skin: 18.2 tonsil: 2.2 -ARHGAP25 KIAA0053 ENSG00000163219 Rho GTPase activating protein 25 2 68679601-68826833 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035346, HPA061395 Supported Approved Nucleoplasm
Vesicles Tissue enhanced 0 spleen: 90.9 lymph node: 82.3 -S100A9 60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14 ENSG00000163220 S100 calcium binding protein A9 1 153357854-153361027 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004193, CAB009441 Supported Supported Nucleoplasm
Cell Junctions
Cytosol Group enriched 6 bone marrow: 21012.0;esophagus: 24343.4 tonsil: 4079.1 -S100A12 CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6 ENSG00000163221 S100 calcium binding protein A12 1 153373706-153375649 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002881, CAB025872 Supported Tissue enriched 19 bone marrow: 2050.6 spleen: 109.0 -TGFA ENSG00000163235 Transforming growth factor, alpha 2 70447280-70554193 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042297 Approved Approved Vesicles Mixed esophagus: 27.4 -TDRD10 DKFZp434M202 ENSG00000163239 Tudor domain containing 10 1 154502219-154548147 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA054327 Approved Vesicles Tissue enriched 12 testis: 76.9 lung: 6.3 -CCNYL1 FLJ40432 ENSG00000163249 Cyclin Y-like 1 2 207711540-207761839 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046825 Approved Approved Plasma membrane Expressed in all testis: 30.3 -FZD5 C2orf31, DKFZP434E2135, HFZ5 ENSG00000163251 Frizzled class receptor 5 2 207762586-207769563 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052361 Approved Mixed duodenum: 20.1 -CRYGC CRYG3 ENSG00000163254 Crystallin, gamma C 2 208128137-208129830 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 9 testis: 2.6 epididymis: 0.2 -DCAF16 C4orf30, FLJ20280 ENSG00000163257 DDB1 and CUL4 associated factor 16 4 17800655-17810758 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042487 Uncertain Approved Plasma membrane
Cytosol Expressed in all endometrium: 22.9 -C1orf189 ENSG00000163263 Chromosome 1 open reading frame 189 1 154199372-154206333 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045779 Uncertain Group enriched 16 fallopian tube: 125.5;testis: 68.3 cervix: 5.9 -NPPC CNP ENSG00000163273 Natriuretic peptide C 2 231921820-231926403 Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA035362 Uncertain Tissue enhanced 0 prostate: 5.7 appendix: 3.0 -GNPDA2 SB52 ENSG00000163281 Glucosamine-6-phosphate deaminase 2 4 44682200-44726595 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000499, HPA046891 Uncertain Approved Golgi apparatus
Vesicles Expressed in all thyroid gland: 32.5 -ALPP ENSG00000163283 Alkaline phosphatase, placental 2 232378534-232382889 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026327, HPA038764, HPA038765, HPA051699 Supported Approved Plasma membrane Group enriched 14 cervix, uterine: 25.2;placenta: 45.5 fallopian tube: 2.5 -GABRG1 ENSG00000163285 Gamma-aminobutyric acid (GABA) A receptor, gamma 1 4 46035769-46124081 FDA approved drug targets, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035622 Approved Tissue enriched 17 cerebral cortex: 26.1 ovary: 1.5 -ALPPL2 ENSG00000163286 Alkaline phosphatase, placental-like 2 2 232406843-232410714 Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB020698, HPA038764, HPA038765, HPA051699 Supported Approved Plasma membrane Tissue enhanced 0 cervix, uterine: 1.1;fallopian tube: 1.9 lung: 0.7 -GABRB1 ENSG00000163288 Gamma-aminobutyric acid (GABA) A receptor, beta 1 4 46993723-47426444 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051297 Uncertain Tissue enriched 15 cerebral cortex: 19.8 heart muscle: 1.3 -PAQR3 ENSG00000163291 Progestin and adipoQ receptor family member III 4 78887127-78939438 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058453 Uncertain Tissue enhanced 0 testis: 1.1 lymph node: 0.3 -NIPAL1 DKFZp686A06115, NPAL1 ENSG00000163293 NIPA-like domain containing 1 4 47914142-48040173 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036765 Uncertain Approved Golgi apparatus Tissue enhanced 0 esophagus: 24.2;skin: 31.0 rectum: 14.9 -ALPI ENSG00000163295 Alkaline phosphatase, intestinal 2 232456123-232460032 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038764, HPA038765, HPA051699 Supported Approved Plasma membrane Group enriched 31 duodenum: 208.8;small intestine: 216.4 colon: 6.8 -ANTXR2 CMG-2, CMG2, FLJ31074 ENSG00000163297 Anthrax toxin receptor 2 4 79901149-80125454 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed smooth muscle: 137.9 -HELQ Hel308 ENSG00000163312 Helicase, POLQ-like 4 83407343-83455856 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036852, HPA036853 Approved Approved Nucleoplasm
Nuclear speckles Mixed adrenal gland: 11.9 -MRPS18C CGI-134, FLJ11146, FLJ22967, MRPS18-1 ENSG00000163319 Mitochondrial ribosomal protein S18C 4 83455932-83469735 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050404 Approved Expressed in all adrenal gland: 38.9 -CGGBP1 CGGBP, p20-CGGBP ENSG00000163320 CGG triplet repeat binding protein 1 3 88051944-88149885 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035568, HPA037017 Supported Validated Nucleus Expressed in all parathyroid gland: 92.3 -FAM175A ABRA1, CCDC98, FLJ13614 ENSG00000163322 Family with sequence similarity 175, member A 4 83459517-83523348 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037654 Uncertain Supported Nuclear bodies Mixed testis: 25.0 -GPR155 DEP.7, DEPDC3, FLJ31819, PGR22 ENSG00000163328 G protein-coupled receptor 155 2 174431571-174487094 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036159, HPA057384 Approved Approved Nuclear bodies
Cytosol Expressed in all stomach: 44.0 -DAPL1 ENSG00000163331 Death associated protein-like 1 2 158795317-158862958 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046937 Approved Nucleoplasm
Mitochondria Tissue enhanced 0 epididymis: 236.1;esophagus: 245.6;skin: 219.1 fallopian tube: 128.2 -PMVK HUMPMKI, PMK, PMKA ENSG00000163344 Phosphomevalonate kinase 1 154924734-154936991 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029900 Approved Expressed in all parathyroid gland: 55.4 -PBXIP1 HPIP ENSG00000163346 Pre-B-cell leukemia homeobox interacting protein 1 1 154944076-154956123 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006949 Approved Approved Vesicles
Cytosol Expressed in all parathyroid gland: 137.9 -CLDN1 ILVASC, SEMP1 ENSG00000163347 Claudin 1 3 190305701-190322475 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002602, HPA048319 Supported Tissue enhanced 0 skin: 306.9;smooth muscle: 183.5 liver: 158.3 -PYGO2 ENSG00000163348 Pygopus family PHD finger 2 1 154957026-154963853 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023689 Supported Approved Nucleoplasm Expressed in all parathyroid gland: 50.7 -HIPK1 KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2 ENSG00000163349 Homeodomain interacting protein kinase 1 1 113929192-113977869 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016664 Approved Approved Nucleoplasm
Centrosome
Cytosol Expressed in all bone marrow: 89.9 -LENEP LEP503 ENSG00000163352 Lens epithelial protein 1 154993586-154994315 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected breast: 0.3 -DCST2 FLJ32934 ENSG00000163354 DC-STAMP domain containing 2 1 155018520-155033781 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 5.1;testis: 4.2 fallopian tube: 1.3 -DCST1 FLJ32785 ENSG00000163357 DC-STAMP domain containing 1 1 155033824-155050930 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA060314 Uncertain Group enriched 5 skin: 3.7;testis: 6.2 small intestine: 0.9 -COL6A3 ENSG00000163359 Collagen, type VI, alpha 3 2 237324003-237414375 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010080 Supported Tissue enhanced 0 smooth muscle: 550.5 gallbladder: 376.5 -C1orf106 FLJ10901 ENSG00000163362 Chromosome 1 open reading frame 106 1 200891048-200915735 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA027499, HPA027511 Uncertain Tissue enhanced 0 small intestine: 71.1 duodenum: 55.8 -YY1AP1 HCCA2, YAP, YY1AP ENSG00000163374 YY1 associated protein 1 1 155659443-155689000 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006986, HPA064249 Uncertain Approved Nucleoli fibrillar center Expressed in all testis: 129.5 -KBTBD8 KIAA1842, TA-KRP ENSG00000163376 Kelch repeat and BTB (POZ) domain containing 8 3 66998307-67011210 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041285, HPA069190 Approved Tissue enhanced 0 lymph node: 24.6;tonsil: 19.7 testis: 14.6 -FAM19A4 TAFA-4 ENSG00000163377 Family with sequence similarity 19 (chemokine (C-C motif)-like), member A4 3 68731766-68953297 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 10 adrenal gland: 18.6 gallbladder: 1.9 -EOGT AER61, C3orf64, FLJ33770 ENSG00000163378 EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 3 68975214-69013961 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019460 Approved Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all seminal vesicle: 49.6 -LMOD3 ENSG00000163380 Leiomodin 3 (fetal) 3 69106872-69123032 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036034 Uncertain Group enriched 17 heart muscle: 69.6;skeletal muscle: 162.3 esophagus: 6.9 -APOA1BP AIBP, MGC119143, MGC119144, MGC119145, YJEFN1 ENSG00000163382 Apolipoprotein A-I binding protein 1 156591762-156594299 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043766, HPA048164 Approved Validated Nucleoplasm
Cytosol Expressed in all epididymis: 110.4 -POGLUT1 9630046K23Rik, C3orf9, hCLP46, KDELCL1, KTELC1, MDS010, MDSRP, MGC32995, Rumi ENSG00000163389 Protein O-glucosyltransferase 1 3 119468938-119494708 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037855 Approved Mixed seminal vesicle: 16.3 -SLC22A15 FLIPT1 ENSG00000163393 Solute carrier family 22, member 15 1 115976498-116070054 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019785 Approved Approved Vesicles Tissue enhanced 0 bone marrow: 20.5 skin: 11.1 -CCKAR ENSG00000163394 Cholecystokinin A receptor 4 26481400-26490462 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 9 gallbladder: 47.3;stomach: 14.9 tonsil: 3.2 -IGFN1 DKFZp434B1231, EEF1A2BP1 ENSG00000163395 Immunoglobulin-like and fibronectin type III domain containing 1 1 201190825-201228952 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050415 Supported Approved Midbody ring Group enriched 6 endometrium: 17.1;epididymis: 18.1;skeletal muscle: 60.2 cerebral cortex: 5.6 -ATP1A1 ENSG00000163399 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1 116372668-116410261 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018702, CAB069993 Supported Expressed in all parathyroid gland: 2441.5 -SLC15A2 PEPT2 ENSG00000163406 Solute carrier family 15 (oligopeptide transporter), member 2 3 121894089-121944102 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cervix, uterine: 77.7;prostate: 66.0 epididymis: 47.2 -EIF4E3 MGC39820 ENSG00000163412 Eukaryotic translation initiation factor 4E family member 3 3 71675416-71754773 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058649 Approved Nucleoli fibrillar center Expressed in all parathyroid gland: 54.8 -PROK2 BV8, KAL4, MIT1, PK2 ENSG00000163421 Prokineticin 2 3 71771656-71785206 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041408 Approved Tissue enhanced 0 appendix: 30.9;bone marrow: 52.8;testis: 24.0 adipose tissue: 11.1 -C3orf30 FLJ32859 ENSG00000163424 Chromosome 3 open reading frame 30 3 119146150-119160042 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA062468 Supported Tissue enriched 365 testis: 93.6 epididymis: 0.2 -LRRC58 ENSG00000163428 Leucine rich repeat containing 58 3 120324509-120349339 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057574 Uncertain Approved Nucleus
Cytosol Expressed in all adrenal gland: 30.3 -FSTL1 FRP, FSL1 ENSG00000163430 Follistatin-like 1 3 120392293-120451253 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035251 Approved Approved Vesicles
Cytosol Expressed in all placenta: 651.3 -LMOD1 1D, 64kD, D1 ENSG00000163431 Leiomodin 1 (smooth muscle) 1 201896452-201946588 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028325, HPA028435, HPA030097 Supported Approved Cytosol Mixed seminal vesicle: 329.3 -ELF3 EPR-1, ERT, ESE-1, ESX ENSG00000163435 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 1 202007945-202017188 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003316, HPA003479 Supported Validated Nucleoplasm Mixed small intestine: 164.9 -PDCL2 GCPHLP ENSG00000163440 Phosducin-like 2 4 55556525-55592212 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048260 Supported Tissue enriched 302 testis: 109.8 skin: 0.3 -TMEM183A C1orf37 ENSG00000163444 Transmembrane protein 183A 1 203007386-203024848 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA072607 Approved Nucleus
Plasma membrane
Cell Junctions Expressed in all testis: 58.5 -TMEM169 FLJ34263 ENSG00000163449 Transmembrane protein 169 2 216081866-216102783 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA070657 Uncertain Approved Focal adhesion sites Tissue enhanced 0 cerebral cortex: 12.0 thyroid gland: 4.8 -IGFBP7 FSTL2, IGFBP-7, MAC25, PSF ENSG00000163453 Insulin-like growth factor binding protein 7 4 57030773-57110385 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002196, CAB020668 Approved Uncertain Golgi apparatus Expressed in all seminal vesicle: 910.8 -TRIM46 FLJ23229, TRIFIC ENSG00000163462 Tripartite motif containing 46 1 155173787-155184971 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030389 Uncertain Approved Intermediate filaments
Cytosol Tissue enhanced 0 cerebral cortex: 7.9 epididymis: 1.8 -KRTCAP2 KCP2 ENSG00000163463 Keratinocyte associated protein 2 1 155169408-155173475 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all epididymis: 236.5 -CXCR1 CD181, CDw128a, CKR-1, CMKAR1, IL8RA ENSG00000163464 Chemokine (C-X-C motif) receptor 1 2 218162845-218166995 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA031991 Uncertain Tissue enhanced 0 appendix: 35.7;spleen: 25.4 adipose tissue: 15.5 -ARPC2 ARC34, p34-Arc ENSG00000163466 Actin related protein 2/3 complex, subunit 2, 34kDa 2 218217094-218254356 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001994, HPA008352 Approved Supported Golgi apparatus
Cytosol Expressed in all lymph node: 544.0 -TSACC C1orf182, SIP, SSTK-IP ENSG00000163467 TSSK6 activating co-chaperone 1 156337314-156346995 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029897 Approved Nucleus
Nuclear bodies Tissue enriched 495 testis: 1500.7 epididymis: 3.0 -CCT3 Cctg, TRIC5 ENSG00000163468 Chaperonin containing TCP1, subunit 3 (gamma) 1 156308968-156367873 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006543 Approved Supported Plasma membrane
Cytosol Expressed in all testis: 205.6 -TMEM79 FLJ16057, FLJ32254, MATT, MGC13102 ENSG00000163472 Transmembrane protein 79 1 156282935-156293185 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA055214 Supported Approved Nucleoli fibrillar center Group enriched 5 esophagus: 61.9;prostate: 45.1;skin: 66.9 tonsil: 11.1 -SSR2 TLAP, TRAPB ENSG00000163479 Signal sequence receptor, beta (translocon-associated protein beta) 1 156009048-156020959 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all epididymis: 541.4 -RNF25 AO7, FLJ13906 ENSG00000163481 Ring finger protein 25 2 218663864-218672411 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036420, HPA036421 Uncertain Approved Nucleoplasm
Cytosol Expressed in all testis: 14.5 -STK36 FU, KIAA1278 ENSG00000163482 Serine/threonine kinase 36 2 218672026-218702716 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027409, HPA027453, HPA030058 Approved Supported Cytosol Expressed in all testis: 58.8 -ADORA1 RDC7 ENSG00000163485 Adenosine A1 receptor 1 203090654-203167405 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044383 Supported Plasma membrane Tissue enhanced 0 cerebral cortex: 46.5;testis: 23.4 parathyroid gland: 17.5 -NEK10 FLJ32685 ENSG00000163491 NIMA-related kinase 10 3 27110085-27369460 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA038941 Uncertain Approved Nucleoplasm
Vesicles Tissue enhanced 0 testis: 65.6 breast: 18.4 -CCDC141 CAMDI, FLJ39502 ENSG00000163492 Coiled-coil domain containing 141 2 178829757-179050086 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012718 Approved Nucleoplasm Tissue enriched 9 heart muscle: 48.7 skeletal muscle: 5.7 -FEV Pet-1 ENSG00000163497 FEV (ETS oncogene family) 2 218981087-218985657 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA067679 Supported Approved Nuclear speckles Tissue enhanced 0 adrenal gland: 2.1;duodenum: 3.0;stomach: 2.4 prostate: 1.9 -CRYBA2 ENSG00000163499 Crystallin, beta A2 2 218990189-218993421 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adrenal gland: 4.6;stomach: 4.6 small intestine: 3.1 -IHH BDA1, HHG2 ENSG00000163501 Indian hedgehog 2 219054420-219060467 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 cervix, uterine: 8.8;colon: 21.4;duodenum: 15.3;endometrium: 31.4;rectum: 16.9;small intestine: 16.8;stomach: 15.6 prostate: 3.1 -KIAA1524 CIP2A ENSG00000163507 KIAA1524 3 108549869-108589644 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039570 Approved Supported Plasma membrane
Cytosol Mixed testis: 10.2 -EOMES TBR2 ENSG00000163508 Eomesodermin 3 27715949-27722711 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028896 Uncertain Tissue enhanced 0 lymph node: 18.4;spleen: 19.7 tonsil: 5.6 -CWC22 EIF4GL, fSAPb, KIAA1604, NCM ENSG00000163510 CWC22 spliceosome-associated protein 2 179944876-180007113 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036748 Approved Supported Nuclear speckles
Cytosol Expressed in all endometrium: 28.8 -AZI2 AZ2, FLJ21939, NAP1 ENSG00000163512 5-azacytidine induced 2 3 28315003-28349127 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035258 Supported Expressed in all testis: 30.7 -TGFBR2 MFS2 ENSG00000163513 Transforming growth factor, beta receptor II (70/80kDa) 3 30606502-30694142 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB073537 Supported Plasma membrane Expressed in all adipose tissue: 290.3 -RETNLB FIZZ2, HXCP2, RELMb ENSG00000163515 Resistin like beta 3 108743424-108757384 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049152 Approved Tissue enhanced 0 colon: 75.2;rectum: 274.6 small intestine: 37.6 -ANKZF1 FLJ10415, ZNF744 ENSG00000163516 Ankyrin repeat and zinc finger domain containing 1 2 219229757-219236669 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035208 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all fallopian tube: 16.8 -HDAC11 ENSG00000163517 Histone deacetylase 11 3 13479724-13506424 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 66.9 -FCRL4 CD307d, FCRH4, IGFP2, IRTA1 ENSG00000163518 Fc receptor-like 4 1 157573749-157598080 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054030 Approved Group enriched 5 appendix: 3.7;lymph node: 4.5;tonsil: 10.1 spleen: 1.2 -TRAT1 HSPC062, TCRIM, TRIM ENSG00000163519 T cell receptor associated transmembrane adaptor 1 3 108822698-108855005 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002356, CAB026130 Supported Tissue enhanced 0 appendix: 14.6;lymph node: 26.8 spleen: 11.7 -FBLN2 ENSG00000163520 Fibulin 2 3 13549131-13638422 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001934, CAB018622 Supported Supported Plasma membrane Mixed adipose tissue: 141.5 -GLB1L MGC10771 ENSG00000163521 Galactosidase, beta 1-like 2 219236606-219245478 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043058 Supported Tissue enhanced 0 testis: 95.1 fallopian tube: 36.8 -STT3B FLJ90106, SIMP, STT3-B ENSG00000163527 STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 3 31532638-31637622 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036448, HPA036646 Approved Supported Endoplasmic reticulum Expressed in all testis: 164.6 -CHCHD4 FLJ31709, MIA40, TIMM40 ENSG00000163528 Coiled-coil-helix-coiled-coil-helix domain containing 4 3 14112077-14124870 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034688, HPA063727 Uncertain Supported Mitochondria Expressed in all parathyroid gland: 30.7 -DPPA2 CT100, PESCRG1 ENSG00000163530 Developmental pluripotency associated 2 3 109293788-109316517 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036134 Uncertain Approved Nucleus Tissue enriched 11 testis: 6.5 placenta: 0.5 -NFASC FLJ46866, KIAA0756, NF, NRCAML ENSG00000163531 Neurofascin 1 204828651-205022822 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008832 Supported Tissue enhanced 0 cerebral cortex: 55.8 seminal vesicle: 22.1 -FCRL1 CD307a, FCRH1, IFGP1, IRTA5 ENSG00000163534 Fc receptor-like 1 1 157794403-157820105 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013323 Approved Tissue enhanced 0 lymph node: 30.7;spleen: 23.9;tonsil: 20.7 appendix: 13.0 -SGOL2 FLJ25211, TRIPIN ENSG00000163535 Shugoshin-like 2 (S. pombe) 2 200510008-200583782 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035163, HPA040817 Supported Validated Nucleoplasm
Nuclear bodies Tissue enriched 6 testis: 59.4 lymph node: 9.3 -SERPINI1 neuroserpin, PI12 ENSG00000163536 Serpin peptidase inhibitor, clade I (neuroserpin), member 1 3 167735243-167825568 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001565, CAB026059, HPA056092 Supported Approved Cytosol Tissue enriched 10 cerebral cortex: 323.2 kidney: 31.1 -CLASP2 KIAA0627 ENSG00000163539 Cytoplasmic linker associated protein 2 3 33496245-33718356 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067071 Supported Golgi apparatus
Cytosol Tissue enriched 6 cerebral cortex: 193.7 endometrium: 33.9 -SUCLG1 ENSG00000163541 Succinate-CoA ligase, alpha subunit 2 84423523-84460045 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036683, HPA036684 Supported Supported Plasma membrane
Mitochondria Expressed in all kidney: 467.4 -NUAK2 FLJ90349, SNARK ENSG00000163545 NUAK family, SNF1-like kinase, 2 1 205302059-205321791 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008958 Uncertain Approved Nucleus
Nucleoli fibrillar center
Cytosol Mixed esophagus: 22.1 -SPTA1 EL2 ENSG00000163554 Spectrin, alpha, erythrocytic 1 1 158610706-158686698 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016193, HPA028048, HPA028253, CAB037246 Supported Tissue enriched 19 bone marrow: 47.1 placenta: 2.4 -PRKCI DXS1179E, PKCI ENSG00000163558 Protein kinase C, iota 3 170222365-170305981 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026574, HPA038635 Approved Validated Microtubules
Cytokinetic bridge
Cytosol Expressed in all thyroid gland: 39.6 -MNDA PYHIN3 ENSG00000163563 Myeloid cell nuclear differentiation antigen 1 158831317-158849506 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034532, HPA073215 Supported Supported Nucleoplasm
Nucleoli Tissue enhanced 0 bone marrow: 195.1;spleen: 147.1 appendix: 114.0 -PYHIN1 IFIX, MGC23885 ENSG00000163564 Pyrin and HIN domain family, member 1 1 158930796-158977054 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051224 Approved Tissue enhanced 0 lymph node: 26.7;spleen: 19.5 tonsil: 11.8 -IFI16 IFNGIP1, PYHIN2 ENSG00000163565 Interferon, gamma-inducible protein 16 1 158999968-159055155 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002134, CAB016293 Supported Supported Nucleus
Nucleoli
Cytosol Expressed in all lymph node: 165.5 -AIM2 PYHIN4 ENSG00000163568 Absent in melanoma 2 1 159062484-159147096 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031365, HPA040309 Uncertain Supported Nucleoplasm
Mitochondria
Cytosol Tissue enhanced 0 lymph node: 53.2;spleen: 31.4;tonsil: 41.8 appendix: 26.9 -EFHB CFAP21, FLJ25200 ENSG00000163576 EF-hand domain family, member B 3 19879472-19947025 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 6 fallopian tube: 25.3;testis: 25.7 cerebral cortex: 4.3 -EIF5A2 ENSG00000163577 Eukaryotic translation initiation factor 5A2 3 170888415-170908693 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029090 Approved Supported Vesicles Tissue enhanced 0 testis: 36.4 smooth muscle: 10.2 -SLC2A2 GLUT2 ENSG00000163581 Solute carrier family 2 (facilitated glucose transporter), member 2 3 170996348-171026750 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010444, HPA028997, HPA028998 Supported Approved Nucleoplasm Tissue enriched 6 liver: 432.5 duodenum: 67.5 -RPL22L1 ENSG00000163584 Ribosomal protein L22-like 1 3 170864875-170870483 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056207 Uncertain Expressed in all appendix: 89.9 -FABP1 L-FABP ENSG00000163586 Fatty acid binding protein 1, liver 2 88122982-88128116 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002305, HPA028275 Supported Approved Nucleoplasm
Cytosol Group enriched 7 colon: 4641.2;duodenum: 4243.6;liver: 5656.0;rectum: 3161.5;small intestine: 4603.3 kidney: 599.7 -PPM1L PP2CE ENSG00000163590 Protein phosphatase, Mg2+/Mn2+ dependent, 1L 3 160755602-161078907 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019891, HPA019953 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 parathyroid gland: 39.0 cerebral cortex: 28.0 -ICA1L ALS2CR14, ALS2CR15 ENSG00000163596 Islet cell autoantigen 1,69kDa-like 2 202773150-202871985 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042507 Approved Supported Mitochondria Mixed epididymis: 22.9 -CTLA4 CD, CD152, CD28, CELIAC3, GSE, ICOS, IDDM12 ENSG00000163599 Cytotoxic T-lymphocyte-associated protein 4 2 203867786-203873960 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 appendix: 24.2;lymph node: 32.3 tonsil: 15.9 -ICOS AILIM, CD278 ENSG00000163600 Inducible T-cell co-stimulator 2 203936748-203961577 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB032575 Approved Tissue enhanced 0 lymph node: 17.1;tonsil: 15.4 bone marrow: 10.9 -RYBP AAP1, DEDAF, YEAF1 ENSG00000163602 RING1 and YY1 binding protein 3 72371825-72446918 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053357, HPA061178 Approved Validated Nucleoplasm Mixed cerebral cortex: 1.7 -PPP4R2 ENSG00000163605 Protein phosphatase 4, regulatory subunit 2 3 72996785-73069199 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034695, HPA039837, HPA073758 Supported Validated Nucleoplasm Expressed in all bone marrow: 66.8 -CD200R1 CD200R, HCRTR2, MOX2R, OX2R ENSG00000163606 CD200 receptor 1 3 112921209-112975122 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 spleen: 14.7 placenta: 10.1 -GTPBP8 HSPC135 ENSG00000163607 GTP-binding protein 8 (putative) 3 112990918-113015060 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA034831, HPA058631 Approved Validated Mitochondria Expressed in all testis: 32.8 -C3orf17 DKFZP434F2021, NET17 ENSG00000163608 Chromosome 3 open reading frame 17 3 113002440-113019861 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069654 Supported Nucleus
Nucleoli Expressed in all testis: 21.7 -SPICE1 CCDC52, SPICE ENSG00000163611 Spindle and centriole associated protein 1 3 113442718-113515187 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064843 Approved Supported Centrosome Mixed endometrium: 17.6 -CCDC191 KIAA1407 ENSG00000163617 Coiled-coil domain containing 191 3 113964137-114056613 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047833 Approved Approved Mitochondria Mixed fallopian tube: 18.6 -CADPS CAPS, CAPS1, KIAA1121 ENSG00000163618 Ca++-dependent secretion activator 3 62398346-62875389 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059328 Supported Approved Vesicles Group enriched 7 adrenal gland: 21.7;cerebral cortex: 94.3 heart muscle: 8.4 -NKX6-1 Nkx6.1, NKX6A ENSG00000163623 NK6 homeobox 1 4 84491987-84498450 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036774, CAB070169 Supported Supported Nucleoplasm Tissue enhanced 0 esophagus: 6.9;thyroid gland: 2.9 testis: 1.4 -CDS1 ENSG00000163624 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 4 84582979-84651338 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036187 Uncertain Approved Nucleus
Nuclear membrane Mixed fallopian tube: 49.0 -WDFY3 ALFY, KIAA0993, ZFYVE25 ENSG00000163625 WD repeat and FYVE domain containing 3 4 84669610-84966391 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042734, HPA048572 Approved Approved Nucleoli
Plasma membrane
Cytosol Expressed in all parathyroid gland: 35.6 -COX18 FLJ38991 ENSG00000163626 COX18 cytochrome c oxidase assembly factor 4 73052362-73069755 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046772, HPA049489 Approved Mixed thyroid gland: 5.5 -PTPN13 PTP-BAS, PTP-BL, PTP1E, PTPL1 ENSG00000163629 Protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 4 86594315-86815171 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002213, HPA065290 Approved Approved Plasma membrane
Cytosol Mixed skin: 66.1 -SYNPR MGC26651, SPO ENSG00000163630 Synaptoporin 3 63228315-63616921 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051368, HPA061671 Supported Tissue enriched 23 cerebral cortex: 78.4 heart muscle: 3.3 -ALB ENSG00000163631 Albumin 4 73397114-73421412 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006262, HPA031024, HPA031025 Supported Validated Endoplasmic reticulum
Golgi apparatus Tissue enriched 221 liver: 105632.0 kidney: 478.5 -C3orf49 ENSG00000163632 Chromosome 3 open reading frame 49 3 63819362-63848636 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053582 Uncertain Tissue enhanced 0 testis: 2.1 cerebral cortex: 1.2 -C4orf36 MGC26744 ENSG00000163633 Chromosome 4 open reading frame 36 4 86876205-86936202 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA057434 Uncertain Approved Focal adhesion sites
Cytosol Tissue enhanced 0 testis: 11.0 skin: 5.9 -THOC7 FLJ23445, fSAP24, NIF3L1BP1 ENSG00000163634 THO complex 7 3 63833870-63863903 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044143 Approved Supported Nuclear speckles
Cytosol Expressed in all breast: 83.8 -ATXN7 ADCAII, OPCA3, SCA7 ENSG00000163635 Ataxin 7 3 63864557-64003462 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034989 Supported Nucleoplasm
Cytosol Expressed in all testis: 33.6 -PSMD6 KIAA0107, p44S10, Rpn7, S10 ENSG00000163636 Proteasome 26S subunit, non-ATPase 6 3 64010549-64024010 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036921, HPA036922 Uncertain Supported Golgi apparatus
Vesicles Expressed in all testis: 215.1 -PRICKLE2 DKFZp686D143 ENSG00000163637 Prickle homolog 2 3 64093867-64445476 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035493 Approved Golgi apparatus
Vesicles Mixed endometrium: 40.5 -ADAMTS9 KIAA1312 ENSG00000163638 ADAM metallopeptidase with thrombospondin type 1 motif, 9 3 64515654-64688000 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028567, HPA028577, HPA028601 Approved Supported Endoplasmic reticulum
Vesicles Tissue enhanced 0 placenta: 45.0 adipose tissue: 31.9 -PPM1K BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm ENSG00000163644 Protein phosphatase, Mg2+/Mn2+ dependent, 1K 4 88257620-88284769 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020066, HPA020862, HPA023891 Approved Supported Mitochondria Expressed in all heart muscle: 60.5 -ERICH6 C3orf44, ERICH6A, FAM194A, MGC39662 ENSG00000163645 Glutamate-rich 6 3 150659885-150703971 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA048373 Supported Tissue enriched 24 testis: 51.4 thyroid gland: 2.1 -CLRN1 RP61, USH3, USH3A ENSG00000163646 Clarin 1 3 150926163-150972999 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA054636 Uncertain Tissue enhanced 0 adrenal gland: 6.8;duodenum: 1.6 testis: 0.8 -GMPS ENSG00000163655 Guanine monophosphate synthase 3 155870536-155944026 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046630 Approved Cytosol Expressed in all testis: 180.7 -TIPARP DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1 ENSG00000163659 TCDD-inducible poly(ADP-ribose) polymerase 3 156673235-156706770 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036796, HPA049230 Uncertain Uncertain Nucleoplasm
Microtubules
Microtubule organizing center Expressed in all parathyroid gland: 228.1 -CCNL1 ania-6a ENSG00000163660 Cyclin L1 3 157146508-157160760 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057911 Supported Nucleoplasm
Nuclear bodies Expressed in all bone marrow: 28.8 -PTX3 TNFAIP5, TSG-14 ENSG00000163661 Pentraxin 3, long 3 157436789-157443628 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069320 Approved Tissue enhanced 0 adipose tissue: 163.4;appendix: 55.0 bone marrow: 52.7 -HESX1 ANF, RPX ENSG00000163666 HESX homeobox 1 3 57197843-57226521 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA024187 Approved Approved Nucleus Tissue enhanced 0 testis: 12.5 epididymis: 5.4 -DCLK3 DCAMKL3, DCDC3C, KIAA1765 ENSG00000163673 Doublecortin-like kinase 3 3 36712422-36739861 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB015207 Uncertain Tissue enhanced 0 testis: 4.9 cerebral cortex: 1.1 -SLMAP KIAA1601, SLAP ENSG00000163681 Sarcolemma associated protein 3 57755450-57929168 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002357, HPA002358 Supported Approved Endoplasmic reticulum Expressed in all smooth muscle: 262.4 -RPL9 L9 ENSG00000163682 Ribosomal protein L9 4 39454124-39458948 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003372 Approved Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all epididymis: 2666.1 -SMIM14 C4orf34, FLJ13289 ENSG00000163683 Small integral membrane protein 14 4 39546330-39639090 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051299 Uncertain Approved Mitochondria Expressed in all liver: 54.1 -RPP14 P14 ENSG00000163684 Ribonuclease P/MRP 14kDa subunit 3 58306247-58324695 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036194 Uncertain Approved Nucleoplasm
Cytosol Expressed in all skeletal muscle: 21.1 -ABHD6 ENSG00000163686 Abhydrolase domain containing 6 3 58237506-58295693 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017283, HPA073225 Uncertain Approved Nucleoplasm
Vesicles Mixed small intestine: 52.0 -DNASE1L3 DNAS1L3, LSD ENSG00000163687 Deoxyribonuclease I-like 3 3 58192257-58214697 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019955 Approved Tissue enhanced 0 spleen: 320.8 liver: 136.1 -C3orf67 FLJ42117, FLJ42930 ENSG00000163689 Chromosome 3 open reading frame 67 3 58717365-59050084 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA069696 Approved Nucleus
Golgi apparatus Tissue enhanced 0 esophagus: 13.3;testis: 46.8 fallopian tube: 6.2 -RBM47 FLJ20273, NET18 ENSG00000163694 RNA binding motif protein 47 4 40423267-40630875 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006347 Approved Supported Nucleoplasm
Cytosol Mixed small intestine: 73.0 -APBB2 FE65L, FE65L1, MGC35575 ENSG00000163697 Amyloid beta (A4) precursor protein-binding, family B, member 2 4 40810027-41216714 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023542 Uncertain Approved Mitochondria Expressed in all thyroid gland: 61.3 -IL17RE FLJ23658 ENSG00000163701 Interleukin 17 receptor E 3 9902612-9916402 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA019011 Uncertain Mixed small intestine: 23.1 -IL17RC IL17-RL ENSG00000163702 Interleukin 17 receptor C 3 9917074-9933630 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA019885, CAB026255, HPA048514 Approved Uncertain Microtubules
Centrosome Expressed in all prostate: 21.3 -CRELD1 AVSD2 ENSG00000163703 Cysteine-rich with EGF-like domains 1 3 9933822-9945413 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026964 Uncertain Approved Nucleoli
Cytosol Expressed in all thyroid gland: 65.6 -PRRT3 FLJ33674 ENSG00000163704 Proline-rich transmembrane protein 3 3 9945542-9952394 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035127, HPA035128 Uncertain Approved Nucleus
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 19.5;parathyroid gland: 27.5 fallopian tube: 12.3 -FANCD2OS C3orf24, MGC40179 ENSG00000163705 FANCD2 opposite strand 3 10081317-10108231 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 17 testis: 54.7 parathyroid gland: 3.3 -PCOLCE2 PCPE2 ENSG00000163710 Procollagen C-endopeptidase enhancer 2 3 142815922-142889203 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013203 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 adipose tissue: 81.4;heart muscle: 57.0;placenta: 57.3 cervix: 28.6 -U2SURP fSAPa, SR140 ENSG00000163714 U2 snRNP-associated SURP domain containing 3 142964497-143060546 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037545, HPA037546, HPA061407 Supported Supported Nucleoplasm Expressed in all testis: 37.2 -MTMR14 C3orf29, FLJ22405, FLJ90311, hEDTP, hJumpy ENSG00000163719 Myotubularin related protein 14 3 9649433-9702394 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054063 Approved Expressed in all lymph node: 42.4 -TTC14 FLJ00166, KIAA1980 ENSG00000163728 Tetratricopeptide repeat domain 14 3 180602130-180617828 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009295 Uncertain Supported Nucleus Expressed in all parathyroid gland: 59.7 -CXCL3 CINC-2b, GRO3, GROg, MIP-2b, SCYB3 ENSG00000163734 Chemokine (C-X-C motif) ligand 3 4 74036589-74038807 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adipose tissue: 26.5;cervix, uterine: 33.4 appendix: 20.8 -CXCL5 ENA-78, SCYB5 ENSG00000163735 Chemokine (C-X-C motif) ligand 5 4 73995642-73998779 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065474 Approved Tissue enhanced 0 appendix: 48.8 urinary bladder: 16.0 -PPBP b-TG1, Beta-TG, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, NAP-2-L1, PBP, SCYB7, TGB, TGB1, THBGB1 ENSG00000163736 Pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 4 73987038-73988197 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008354, CAB017624 Supported Tissue enhanced 0 bone marrow: 111.1;spleen: 24.7 placenta: 15.1 -PF4 CXCL4, SCYB4 ENSG00000163737 Platelet factor 4 4 73981077-73982124 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026008, HPA052485 Supported Group enriched 5 bone marrow: 53.9;spleen: 13.7 placenta: 6.4 -MTHFD2L MGC72244 ENSG00000163738 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 4 74114174-74303099 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035434 Uncertain Mixed adrenal gland: 4.9 -CXCL1 FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1 ENSG00000163739 Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 4 73869393-73871242 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cervix, uterine: 177.9;spleen: 115.0 urinary bladder: 95.4 -RCHY1 ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363 ENSG00000163743 Ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 4 75479037-75514764 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030339 Approved Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 31.5 -PLSCR2 ENSG00000163746 Phospholipid scramblase 2 3 146391421-146495991 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 testis: 23.4 epididymis: 2.2 -CCDC158 FLJ25770 ENSG00000163749 Coiled-coil domain containing 158 4 76312997-76421868 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 27 testis: 60.1 thyroid gland: 2.2 -CPA3 ENSG00000163751 Carboxypeptidase A3 (mast cell) 3 148865256-148897196 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006479, HPA008689, CAB020712 Supported Tissue enhanced 0 gallbladder: 174.4 lung: 126.7 -GYG1 GYG ENSG00000163754 Glycogenin 1 3 148991341-149027668 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030497 Approved Supported Vesicles Expressed in all testis: 209.4 -HPS3 BLOC2S1, SUTAL ENSG00000163755 Hermansky-Pudlak syndrome 3 3 149129584-149173732 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046281, HPA052778 Approved Approved Golgi apparatus
Plasma membrane Mixed spleen: 22.5 -TM4SF18 L6D ENSG00000163762 Transmembrane 4 L six family member 18 3 149318498-149334414 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053639, HPA069378 Approved Uncertain Nucleoli
Vesicles Mixed spleen: 47.6 -TOPBP1 KIAA0259, TOP2BP1 ENSG00000163781 Topoisomerase (DNA) II binding protein 1 3 133598175-133661893 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022451, HPA036738, HPA036739 Approved Validated Nucleus Expressed in all testis: 54.0 -RYK D3S3195, JTK5, JTK5A, RYK1 ENSG00000163785 Receptor-like tyrosine kinase 3 134065303-134250744 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB034117, HPA045503 Uncertain Approved Nucleus
Nucleoli fibrillar center Expressed in all ovary: 100.7 -SNRK FLJ20224, HSNFRK, KIAA0096 ENSG00000163788 SNF related kinase 3 43286512-43424764 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042163 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cell Junctions Expressed in all placenta: 47.5 -TCF23 bHLHa24, OUT ENSG00000163792 Transcription factor 23 2 27149004-27156974 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 endometrium: 33.7;ovary: 22.6;smooth muscle: 30.5 fallopian tube: 13.9 -DNAJC5G CSP-gamma, FLJ40417 ENSG00000163793 DnaJ (Hsp40) homolog, subfamily C, member 5 gamma 2 27275421-27281499 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041445 Approved Group enriched 40 epididymis: 63.9;testis: 42.6 cerebral cortex: 1.3 -UCN UI, UROC ENSG00000163794 Urocortin 2 27307400-27308445 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB010911 Approved Approved Endoplasmic reticulum Mixed cerebral cortex: 2.8 -ZNF513 FLJ32203, RP58 ENSG00000163795 Zinc finger protein 513 2 27377231-27380790 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA051493 Uncertain Expressed in all testis: 25.9 -SLC4A1AP HLC3, kanadaptin ENSG00000163798 Solute carrier family 4 (anion exchanger), member 1, adaptor protein 2 27663471-27694976 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036679 Approved Supported Nucleoplasm
Vesicles Expressed in all testis: 61.8 -PLB1 FLJ30866, PLB ENSG00000163803 Phospholipase B1 2 28457145-28643788 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014045 Approved Cytosol Group enriched 7 skin: 9.5;small intestine: 46.5 testis: 4.2 -SPDYA Ringo3, SPDY1, SPY1 ENSG00000163806 Speedy/RINGO cell cycle regulator family member A 2 28782517-28850611 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035162, HPA066214 Supported Supported Nucleoplasm Tissue enriched 30 testis: 58.5 skin: 1.9 -KIAA1143 ENSG00000163807 KIAA1143 3 44737661-44761662 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045018, HPA061799 Approved Approved Nucleus
Cytokinetic bridge Expressed in all parathyroid gland: 15.1 -KIF15 HKLP2, KNSL7, NY-BR-62 ENSG00000163808 Kinesin family member 15 3 44761717-44873376 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035516, HPA035517 Approved Tissue enhanced 0 testis: 14.1 bone marrow: 3.1 -TGM4 TGP ENSG00000163810 Transglutaminase 4 3 44874608-44914990 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032072, CAB033571 Supported Tissue enriched 463 prostate: 688.5 adrenal gland: 1.4 -WDR43 KIAA0007, NET12, UTP5 ENSG00000163811 WD repeat domain 43 2 28894643-28948222 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044733 Uncertain Expressed in all testis: 36.3 -ZDHHC3 GODZ, ZNF373 ENSG00000163812 Zinc finger, DHHC-type containing 3 3 44915257-44976185 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012465, HPA016616 Approved Approved Golgi apparatus Expressed in all skin: 65.4 -CDCP1 CD318, SIMA135 ENSG00000163814 CUB domain containing protein 1 3 45082278-45146422 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010978, HPA010979, CAB025637 Supported Mixed skin: 27.8 -CLEC3B TN, TNA ENSG00000163815 C-type lectin domain family 3, member B 3 45001548-45036071 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002582, HPA034794 Approved Tissue enhanced 0 spleen: 309.1 adipose tissue: 203.5 -SLC6A20 XT3, Xtrp3 ENSG00000163817 Solute carrier family 6 (proline IMINO transporter), member 20 3 45755450-45796535 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029873 Approved Tissue enhanced 0 duodenum: 25.1;small intestine: 19.7 gallbladder: 10.9 -LZTFL1 BBS17 ENSG00000163818 Leucine zipper transcription factor-like 1 3 45823316-45916042 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043466, HPA048447 Supported Supported Cytosol Mixed testis: 35.8 -FYCO1 FLJ13335, ZFYVE7 ENSG00000163820 FYVE and coiled-coil domain containing 1 3 45917899-45995824 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035526, HPA057966 Uncertain Validated Vesicles Expressed in all skeletal muscle: 91.9 -CCR1 CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1 ENSG00000163823 Chemokine (C-C motif) receptor 1 3 46201709-46208396 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 58.8 spleen: 41.7 -RTP3 LTM1, TMEM7, Z3CXXC3 ENSG00000163825 Receptor (chemosensory) transporter protein 3 3 46497491-46500949 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA075932 Uncertain Mitochondria Tissue enriched 24 liver: 33.7 testis: 1.4 -LRRC2 ENSG00000163827 Leucine rich repeat containing 2 3 46515423-46580099 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039138, HPA040096 Approved Group enriched 5 heart muscle: 27.7;skeletal muscle: 56.0;thyroid gland: 36.8 endometrium: 7.8 -ELP6 C3orf75, FLJ20211, TMEM103 ENSG00000163832 Elongator acetyltransferase complex subunit 6 3 47495640-47513761 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046358, HPA064545 Uncertain Approved Nucleus
Centrosome
Cytosol Expressed in all testis: 32.0 -FBXO40 Fbx40, KIAA1195 ENSG00000163833 F-box protein 40 3 121593119-121630295 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 47 heart muscle: 62.3;skeletal muscle: 54.0 esophagus: 1.2 -DTX3L BBAP ENSG00000163840 Deltex 3 like, E3 ubiquitin ligase 3 122564238-122575203 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010570 Uncertain Supported Nucleoplasm
Cytosol Expressed in all spleen: 36.7 -ZNF148 BERF-1, BFCOL1, HT-BETA, pHZ-52, ZBP-89, ZFP148 ENSG00000163848 Zinc finger protein 148 3 125225561-125375354 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001656, CAB017486 Supported Supported Nucleus
Golgi apparatus Expressed in all thyroid gland: 50.2 -NMNAT3 PNAT3 ENSG00000163864 Nicotinamide nucleotide adenylyltransferase 3 3 139560180-139678017 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039077, HPA057402 Approved Supported Mitochondria Mixed fallopian tube: 22.7 -SMIM12 C1orf212, FLJ90372 ENSG00000163866 Small integral membrane protein 12 1 34712737-34859816 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065331 Approved Approved Mitochondria Expressed in all smooth muscle: 44.8 -ZMYM6 Buster2, MYM, ZBED7, ZNF198L4, ZNF258 ENSG00000163867 Zinc finger, MYM-type 6 1 34986165-35031968 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011004, HPA071865 Approved Supported Nucleoplasm Mixed testis: 18.9 -TPRA1 FLJ32197, GPR175, TMEM227, TPRA40 ENSG00000163870 Transmembrane protein, adipocyte asscociated 1 3 127573069-127598251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA019784 Approved Approved Vesicles Expressed in all parathyroid gland: 38.1 -YEATS2 FLJ10201, FLJ12841, FLJ13308, KIAA1197 ENSG00000163872 YEATS domain containing 2 3 183697818-183812625 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045891 Uncertain Approved Nucleoplasm Mixed cerebral cortex: 19.5 -GRIK3 GluK3, GLUR7 ENSG00000163873 Glutamate receptor, ionotropic, kainate 3 1 36795527-37034129 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 6 cerebral cortex: 19.8 seminal vesicle: 3.5 -ZC3H12A FLJ23231, MCPIP1 ENSG00000163874 Zinc finger CCCH-type containing 12A 1 37474552-37484379 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032052, HPA032053 Uncertain Supported Nucleoplasm
Cytoplasmic bodies Tissue enhanced 0 bone marrow: 114.3 gallbladder: 76.1 -MEAF6 C1orf149, CENP-28, Eaf6, FLJ11730, NY-SAR-91 ENSG00000163875 MYST/Esa1-associated factor 6 1 37492575-37514774 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029599 Supported Nucleoplasm
Nuclear bodies Expressed in all prostate: 145.0 -SNIP1 ENSG00000163877 Smad nuclear interacting protein 1 1 37534449-37554302 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036896 Approved Supported Nucleoplasm
Cytosol Mixed testis: 12.2 -DNALI1 dJ423B22.5, hp28, P28 ENSG00000163879 Dynein, axonemal, light intermediate chain 1 1 37556919-37566857 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028305 Approved Tissue enhanced 0 fallopian tube: 85.2 testis: 38.2 -POLR2H RPB8 ENSG00000163882 Polymerase (RNA) II (DNA directed) polypeptide H 3 184361718-184368596 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037745, HPA055813 Supported Supported Nucleus Expressed in all cervix: 71.3 -KLF15 KKLF ENSG00000163884 Kruppel-like factor 15 3 126342635-126357442 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA028866 Uncertain Tissue enhanced 0 ovary: 42.7 adipose tissue: 37.0 -CFAP100 CCDC37, FLJ40083, MIA1 ENSG00000163885 Cilia and flagella associated protein 100 3 126394939-126436556 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046354 Approved Group enriched 5 fallopian tube: 43.0;testis: 34.3 lung: 7.5 -CAMK2N2 CaM-KIIN ENSG00000163888 Calcium/calmodulin-dependent protein kinase II inhibitor 2 3 184259213-184261463 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA050835 Supported Nucleus
Centrosome Tissue enhanced 0 adrenal gland: 12.3;cerebral cortex: 40.5 pancreas: 5.6 -LIPH LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B ENSG00000163898 Lipase, member H 3 185506262-185552613 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049079 Approved Tissue enhanced 0 rectum: 41.5;stomach: 45.3 colon: 36.4 -TMEM41A MGC15397 ENSG00000163900 Transmembrane protein 41A 3 185476496-185499057 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059101, HPA059790 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all adrenal gland: 28.3 -RPN1 OST1 ENSG00000163902 Ribophorin I 3 128619970-128681075 Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009748, HPA026828, HPA051520 Supported Validated Endoplasmic reticulum Expressed in all epididymis: 416.3 -SENP2 AXAM2, DKFZp762A2316, KIAA1331, SMT3IP2 ENSG00000163904 SUMO1/sentrin/SMT3 specific peptidase 2 3 185582496-185633551 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029247, HPA029248 Approved Supported Cytosol Expressed in all testis: 26.8 -HEYL bHLHb33, HESR3, HEY3 ENSG00000163909 Hes-related family bHLH transcription factor with YRPW motif-like 1 39624153-39639945 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001438 Approved Mitochondria
Cytosol Mixed placenta: 44.0 -IFT122 SPG, WDR10, WDR10p, WDR140 ENSG00000163913 Intraflagellar transport 122 3 129440036-129520507 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041815 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 147.3 -RHO CSNBAD1, OPN2, RP4 ENSG00000163914 Rhodopsin 3 129528640-129535169 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013440, CAB022486 Supported Not detected cerebral cortex: 0.3 -RFC4 A1, RFC37 ENSG00000163918 Replication factor C (activator 1) 4, 37kDa 3 186789880-186807058 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004557, HPA049123, HPA058507 Supported Validated Nucleoplasm Expressed in all testis: 40.5 -RPL39L RPL39L1 ENSG00000163923 Ribosomal protein L39-like 3 187120948-187180908 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047105 Approved Tissue enriched 14 testis: 222.5 breast: 16.1 -BAP1 hucep-6, KIAA0272, UCHL2 ENSG00000163930 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 3 52401013-52410350 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004322, HPA028814, HPA028815, HPA055560 Approved Validated Nucleoplasm
Cytosol Expressed in all testis: 118.1 -TKT ENSG00000163931 Transketolase 3 53224707-53256052 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029480, HPA029481 Supported Validated Nucleoplasm Expressed in all bone marrow: 432.0 -PRKCD ENSG00000163932 Protein kinase C, delta 3 53156009-53192717 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001863, HPA001890, CAB010469, CAB013225 Supported Validated Endoplasmic reticulum
Golgi apparatus
Cytosol Mixed adrenal gland: 70.7 -RFT1 CDG1N ENSG00000163933 RFT1 homolog 3 53088483-53130462 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060327 Approved Vesicles Expressed in all testis: 25.8 -SFMBT1 DKFZp434L243, RU1, SFMBT ENSG00000163935 Scm-like with four mbt domains 1 3 52903572-53046750 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036152, HPA036153, HPA064564 Uncertain Validated Nucleoplasm Group enriched 6 parathyroid gland: 32.5;testis: 82.9 thyroid gland: 9.9 -GNL3 C77032, E2IG3, MGC800, NS ENSG00000163938 Guanine nucleotide binding protein-like 3 (nucleolar) 3 52681156-52694492 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020770, HPA036742, HPA036743 Supported Validated Nucleoli
Nuclear bodies Expressed in all breast: 78.2 -PBRM1 BAF180, PB1 ENSG00000163939 Polybromo 1 3 52545352-52685917 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015629, HPA059373 Uncertain Supported Nucleoplasm Expressed in all thyroid gland: 44.5 -UVSSA KIAA1530 ENSG00000163945 UV-stimulated scaffold protein A 4 1347266-1388049 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050824, HPA053496 Approved Approved Nucleoplasm Mixed testis: 12.2 -FAM208A C3orf63, KIAA1105, RAP140, se89-1 ENSG00000163946 Family with sequence similarity 208, member A 3 56620133-56683237 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006735, HPA017142 Uncertain Validated Nucleoplasm Mixed testis: 53.2 -ARHGEF3 DKFZP434F2429, GEF3, STA3, XPLN ENSG00000163947 Rho guanine nucleotide exchange factor (GEF) 3 3 56727418-57079329 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA034715, HPA064945 Uncertain Approved Cytosol Expressed in all endometrium: 64.6 -SLBP HBP ENSG00000163950 Stem-loop binding protein 4 1692800-1712555 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019254, HPA061670 Supported Supported Nucleus
Nucleoli
Cytosol Expressed in all testis: 130.2 -LRPAP1 A2MRAP, HBP44 ENSG00000163956 Low density lipoprotein receptor-related protein associated protein 1 4 3506376-3532559 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008001, CAB025518 Supported Supported Validated Endoplasmic reticulum Expressed in all placenta: 13.6 -ZDHHC19 MGC33345 ENSG00000163958 Zinc finger, DHHC-type containing 19 3 196197449-196211437 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 44 testis: 29.2 adrenal gland: 0.6 -SLC51A OSTalpha ENSG00000163959 Solute carrier family 51, alpha subunit 3 196211487-196243178 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039123 Approved Tissue enhanced 0 duodenum: 30.1;liver: 35.2;small intestine: 72.7 colon: 10.2 -UBXN7 KIAA0794, UBXD7 ENSG00000163960 UBX domain protein 7 3 196347662-196432474 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048441, HPA049442 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 22.3 -RNF168 FLJ35794 ENSG00000163961 Ring finger protein 168, E3 ubiquitin protein ligase 3 196468783-196503768 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046109 Validated Nucleoplasm
Nuclear bodies Mixed testis: 20.3 -PIGX FLJ20522 ENSG00000163964 Phosphatidylinositol glycan anchor biosynthesis, class X 3 196639775-196736007 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029409 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 28.0 -MFI2 CD228, FLJ38863, MAP97, MGC4856, MTf, MTF1 ENSG00000163975 Antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 3 196988621-197029816 CD markers, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004880 Approved Tissue enhanced 0 parathyroid gland: 31.9;salivary gland: 28.3 small intestine: 9.8 -OTOP1 ENSG00000163982 Otopetrin 1 4 4188803-4226889 Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA035599 Uncertain Not detected skin: 0.2 -S100P ENSG00000163993 S100 calcium binding protein P 4 6693069-6697170 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019502 Supported Supported Nuclear bodies Tissue enhanced 0 bone marrow: 169.8;stomach: 368.1;urinary bladder: 185.5 placenta: 130.1 -ABLIM2 KIAA1808 ENSG00000163995 Actin binding LIM protein family, member 2 4 7965310-8158832 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035808 Uncertain Approved Nucleoplasm
Mitochondria Tissue enhanced 0 skeletal muscle: 37.7;spleen: 28.9 cerebral cortex: 22.2 -EXO5 C1orf176, DEM1, FLJ21144 ENSG00000164002 Exonuclease 5 1 40508741-40516556 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028429 Supported Nucleoplasm
Cytosol Mixed smooth muscle: 11.2 -CLDN19 ENSG00000164007 Claudin 19 1 42733093-42740254 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 12 kidney: 19.6;placenta: 14.4 breast: 1.4 -C1orf50 MGC955 ENSG00000164008 Chromosome 1 open reading frame 50 1 42767269-42794493 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030236 Uncertain Expressed in all testis: 20.0 -ERMAP BTN5, RD, SC ENSG00000164010 Erythroblast membrane-associated protein (Scianna blood group) 1 42817124-42844989 Blood group antigen proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042573 Uncertain Mixed thyroid gland: 18.8 -ZNF691 Zfp691 ENSG00000164011 Zinc finger protein 691 1 42846573-42852477 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062527 Approved Approved Nucleus
Nucleoli
Vesicles Expressed in all parathyroid gland: 21.4 -AIMP1 EMAP-2, EMAPII, p43, SCYE1 ENSG00000164022 Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 4 106315544-106349226 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017618, HPA018476 Supported Validated Cytosol Expressed in all thyroid gland: 63.0 -SGMS2 MGC26963, SMS2 ENSG00000164023 Sphingomyelin synthase 2 4 107824563-107915047 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015076 Supported Mixed gallbladder: 64.5 -METAP1 KIAA0094, MAP1A, MetAP1A ENSG00000164024 Methionyl aminopeptidase 1 4 98995620-99062813 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025485, HPA037997, HPA037998 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 76.9 -DNAJB14 FLJ14281 ENSG00000164031 DnaJ (Hsp40) homolog, subfamily B, member 14 4 99896248-99946726 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036016 Approved Expressed in all cerebral cortex: 34.8 -H2AFZ H2A.Z, H2AZ ENSG00000164032 H2A histone family, member Z 4 99948086-99950388 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB022549, HPA057236 Supported Supported Nucleoplasm Expressed in all lymph node: 354.3 -EMCN MUC14 ENSG00000164035 Endomucin 4 100395341-100880126 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005928 Approved Mixed kidney: 82.9 -SLC9B1 NHA1, NHEDC1 ENSG00000164037 Solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 4 102885048-103019739 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA035435, HPA058971, HPA065520 Uncertain Approved Mitochondria Tissue enriched 25 testis: 73.9 epididymis: 2.9 -SLC9B2 FLJ23984, NHA2, NHEDC2 ENSG00000164038 Solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 4 103019868-103085829 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047008 Uncertain Approved Nucleoplasm
Cell Junctions Tissue enhanced 0 cerebral cortex: 32.6 liver: 20.5 -BDH2 DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308 ENSG00000164039 3-hydroxybutyrate dehydrogenase, type 2 4 103079435-103099883 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036028, HPA036029 Supported Supported Cytosol Expressed in all kidney: 452.1 -PGRMC2 DG6, PMBP ENSG00000164040 Progesterone receptor membrane component 2 4 128269237-128288829 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041172, HPA058652 Approved Approved Nuclear bodies
Plasma membrane
Cytosol Expressed in all small intestine: 136.2 -CDC25A ENSG00000164045 Cell division cycle 25A 3 48157146-48188402 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA005855 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Tissue enhanced 0 testis: 24.4 bone marrow: 9.3 -CAMP CAP18, FALL-39, FALL39, LL37 ENSG00000164047 Cathelicidin antimicrobial peptide 3 48223347-48225491 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB015949, CAB016522, HPA029874 Supported Group enriched 99 bone marrow: 1343.7;epididymis: 324.9 lymph node: 8.4 -ZNF589 SZF1 ENSG00000164048 Zinc finger protein 589 3 48241100-48299253 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA003145 Uncertain Approved Nucleoplasm Mixed prostate: 27.8 -FBXW12 Fbw12, FBXO35 ENSG00000164049 F-box and WD repeat domain containing 12 3 48372219-48401259 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037491, HPA037492 Uncertain Group enriched 5 pancreas: 1.2;testis: 1.1 cerebral cortex: 0.2 -PLXNB1 KIAA0407, PLXN5, SEP ENSG00000164050 Plexin B1 3 48403854-48430051 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040586 Approved Mixed fallopian tube: 36.3 -CCDC51 FLJ12436 ENSG00000164051 Coiled-coil domain containing 51 3 48432164-48440456 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010980, HPA011408 Supported Supported Nucleoplasm
Centrosome
Mitochondria Mixed thyroid gland: 17.2 -ATRIP FLJ12343, MGC20625, MGC21482, MGC26740 ENSG00000164053 ATR interacting protein 3 48446710-48465716 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033109, HPA047590 Approved Approved Nucleus Tissue enhanced 0 testis: 31.4 thyroid gland: 10.5 -SHISA5 hShisa5, SCOTIN ENSG00000164054 Shisa family member 5 3 48467798-48504826 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042295 Approved Expressed in all placenta: 197.8 -SPRY1 hSPRY1 ENSG00000164056 Sprouty RTK signaling antagonist 1 4 123396795-123403760 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB013538, HPA051369, HPA070554 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all gallbladder: 132.5 -BSN ZNF231 ENSG00000164061 Bassoon presynaptic cytomatrix protein 3 49554489-49671545 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA034757 Approved Tissue enriched 6 cerebral cortex: 28.3 epididymis: 4.7 -APEH D3F15S2, D3S48E, DNF15S2 ENSG00000164062 Acylaminoacyl-peptide hydrolase 3 49674002-49683963 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029700, HPA029701, HPA029702, HPA029703 Supported Validated Cytosol Expressed in all parathyroid gland: 99.6 -INTU KIAA1284, PDZD6, PDZK6 ENSG00000164066 Inturned planar cell polarity protein 4 127623271-127726737 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036714, HPA036715 Approved Approved Vesicles Mixed epididymis: 8.3 -RNF123 FLJ12565 ENSG00000164068 Ring finger protein 123 3 49689499-49721529 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065983, HPA071879 Approved Approved Cytosol Expressed in all skeletal muscle: 53.3 -HSPA4L APG-1, HSPH3, Osp94 ENSG00000164070 Heat shock 70kDa protein 4-like 4 127781821-127840733 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034450, HPA039149, HPA061446 Supported Approved Centrosome
Cytosol Tissue enriched 8 testis: 192.3 parathyroid gland: 23.7 -MFSD8 CLN7, MGC33302 ENSG00000164073 Major facilitator superfamily domain containing 8 4 127917805-127965995 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044802 Approved Supported Nucleoplasm
Vesicles Expressed in all parathyroid gland: 12.2 -ABHD18 C4orf29, FLJ21106 ENSG00000164074 Abhydrolase domain containing 18 4 127965306-128039711 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA050168, HPA051676 Approved Approved Nuclear membrane Expressed in all heart muscle: 9.5 -CAMKV MGC8407, VACAMKL ENSG00000164076 CaM kinase-like vesicle-associated 3 49857988-49870222 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA007656, CAB034931 Supported Approved Nucleoplasm
Cytokinetic bridge Tissue enriched 55 cerebral cortex: 86.5 testis: 1.5 -MON1A MGC13272, SAND1 ENSG00000164077 MON1 secretory trafficking family member A 3 49908862-49930173 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053752, HPA058032 Uncertain Approved Cytosol Mixed duodenum: 14.9 -MST1R CD136, CDw136, PTK8, RON ENSG00000164078 Macrophage stimulating 1 receptor 3 49887002-49903873 CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007657, HPA008180, CAB008972 Approved Approved Cytosol Tissue enhanced 0 skin: 69.4 stomach: 37.4 -RAD54L2 ARIP4, KIAA0809, SRISNF2L ENSG00000164080 RAD54-like 2 (S. cerevisiae) 3 51541144-51668667 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035004, HPA039992 Supported Nucleus
Cytosol Expressed in all testis: 8.8 -TEX264 FLJ13935, ZSIG11 ENSG00000164081 Testis expressed 264 3 51662693-51704323 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005002, HPA017739 Supported Supported Nucleoli
Cytosol Expressed in all testis: 112.9 -GRM2 GPRC1B, mGlu2, MGLUR2 ENSG00000164082 Glutamate receptor, metabotropic 2 3 51707070-51718613 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065166 Approved Tissue enriched 10 cerebral cortex: 4.4 testis: 0.4 -DUSP7 MKP-X, PYST2 ENSG00000164086 Dual specificity phosphatase 7 3 52048919-52056550 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all skin: 45.2 -POC1A DKFZP434C245, WDR51A ENSG00000164087 POC1 centriolar protein A 3 52075253-52154690 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040600 Approved Tissue enhanced 0 testis: 23.1 bone marrow: 7.0 -PPM1M FLJ32332, PP2Ceta ENSG00000164088 Protein phosphatase, Mg2+/Mn2+ dependent, 1M 3 52245793-52250597 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036905, HPA062291 Uncertain Approved Nuclear bodies Expressed in all lung: 34.9 -ETNPPL AGXT2L1 ENSG00000164089 Ethanolamine-phosphate phospho-lyase 4 108742040-108763054 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044546, HPA072938 Approved Approved Nucleus Group enriched 8 cerebral cortex: 141.6;liver: 98.5 stomach: 14.7 -WDR82 MST107, MSTP107, PRO2730, PRO34047, SWD2, TMEM113, WDR82A ENSG00000164091 WD repeat domain 82 3 52254421-52288020 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040427 Approved Nucleoli Expressed in all endometrium: 93.1 -PITX2 ARP1, Brx1, IGDS, IHG2, IRID2, Otlx2, RGS, RIEG, RIEG1, RS ENSG00000164093 Paired-like homeodomain 2 4 110617423-110642123 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA050074, HPA062728 Validated Nucleus Tissue enhanced 0 placenta: 71.9 skeletal muscle: 18.3 -C4orf3 ENSG00000164096 Chromosome 4 open reading frame 3 4 119296419-119304445 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026907 Approved Approved Cytosol Expressed in all esophagus: 151.2 -PRSS12 BSSP-3, MRT1 ENSG00000164099 Protease, serine, 12 (neurotrypsin, motopsin) 4 118280038-118353003 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035054, HPA035055 Uncertain Approved Nucleus
Actin filaments Mixed cervix: 22.3 -NDST3 HSST3 ENSG00000164100 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 4 118033618-118258648 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056189 Uncertain Tissue enhanced 0 cerebral cortex: 3.0;spleen: 2.8 cervix: 0.7 -HMGB2 HMG2 ENSG00000164104 High mobility group box 2 4 173331695-173335125 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003506, CAB037206, HPA053314 Supported Supported Nucleus
Nucleoli Expressed in all bone marrow: 1466.9 -SAP30 ENSG00000164105 Sin3A-associated protein, 30kDa 4 173369969-173377532 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022627, HPA059012 Supported Supported Nucleoplasm Expressed in all testis: 34.7 -SCRG1 SCRG-1 ENSG00000164106 Stimulator of chondrogenesis 1 4 173384701-173406380 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA012882 Approved Tissue enhanced 0 cerebral cortex: 24.5;testis: 15.6 smooth muscle: 11.1 -HAND2 bHLHa26, dHand, Hed, Thing2 ENSG00000164107 Heart and neural crest derivatives expressed 2 4 173524969-173530229 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019591, CAB025576 Approved Supported Nucleoplasm
Vesicles Tissue enhanced 0 endometrium: 83.7 smooth muscle: 77.6 -MAD2L1 HSMAD2, MAD2 ENSG00000164109 MAD2 mitotic arrest deficient-like 1 (yeast) 4 120055608-120067074 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003348 Uncertain Approved Nucleoplasm Mixed lymph node: 4.6 -ANXA5 ANX5, ENX2 ENSG00000164111 Annexin A5 4 121667955-121697113 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003677, HPA035330 Approved Approved Nuclear membrane Expressed in all placenta: 612.8 -TMEM155 FLJ30834 ENSG00000164112 Transmembrane protein 155 4 121758933-121765427 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 5 cerebral cortex: 27.7;placenta: 5.7 lymph node: 3.0 -ADAD1 Tenr ENSG00000164113 Adenosine deaminase domain containing 1 (testis-specific) 4 122378966-122429802 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 2108 testis: 210.7 adipose tissue: 0.0 -MAP9 ASAP, FLJ21159 ENSG00000164114 Microtubule-associated protein 9 4 155342658-155376970 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037864 Uncertain Tissue enhanced 0 parathyroid gland: 78.4 cerebral cortex: 27.2 -GUCY1A3 GC-SA3, GUC1A3 ENSG00000164116 Guanylate cyclase 1, soluble, alpha 3 4 155666711-155732349 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010887, HPA056004 Uncertain Supported Nucleoplasm
Cytosol Tissue enhanced 0 parathyroid gland: 134.2 smooth muscle: 43.3 -FBXO8 FBS, FBX8 ENSG00000164117 F-box protein 8 4 174236658-174284264 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA002885 Uncertain Approved Nucleoplasm
Cytosol Expressed in all placenta: 44.1 -CEP44 KIAA1712 ENSG00000164118 Centrosomal protein 44kDa 4 174283677-174333380 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041515, HPA041835 Approved Mixed testis: 23.5 -HPGD SDR36C1 ENSG00000164120 Hydroxyprostaglandin dehydrogenase 15-(NAD) 4 174490177-174523154 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004919, HPA005679 Supported Supported Nucleoplasm
Cytosol Tissue enhanced 0 urinary bladder: 389.1 stomach: 183.4 -ASB5 ENSG00000164122 Ankyrin repeat and SOCS box containing 5 4 176213673-176277571 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028870 Uncertain Plasma membrane Tissue enhanced 0 skeletal muscle: 75.7 prostate: 18.1 -C4orf45 FLJ25371 ENSG00000164123 Chromosome 4 open reading frame 45 4 158893134-159038760 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 49 testis: 19.9 bone marrow: 0.4 -TMEM144 FLJ11155 ENSG00000164124 Transmembrane protein 144 4 158201604-158255411 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043767, HPA063554 Uncertain Approved Mitochondria Tissue enhanced 0 cerebral cortex: 90.8 testis: 46.6 -FAM198B C4orf18, DKFZp434L142, FLJ38155 ENSG00000164125 Family with sequence similarity 198, member B 4 158124474-158173318 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA007227 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus Expressed in all adrenal gland: 272.9 -NPY1R NPYR ENSG00000164128 Neuropeptide Y receptor Y1 4 163323961-163344832 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029903 Approved Nucleus
Mitochondria
Cytosol Tissue enhanced 0 spleen: 153.9 breast: 39.0 -NPY5R NPYR5 ENSG00000164129 Neuropeptide Y receptor Y5 4 163343939-163351934 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 spleen: 12.5;testis: 9.6 adipose tissue: 7.6 -NAA15 FLJ13340, NARG1, NATH, TBDN100 ENSG00000164134 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 4 139301455-139420033 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023589, HPA050661 Approved Validated Cytosol Expressed in all testis: 24.1 -IL15 IL-15, MGC9721 ENSG00000164136 Interleukin 15 4 141636599-141733987 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB004457, HPA037738 Uncertain Supported Nucleoplasm
Nuclear speckles Tissue enhanced 0 breast: 45.7 spleen: 19.1 -FAM160A1 FLJ43373 ENSG00000164142 Family with sequence similarity 160, member A1 4 151409216-151663632 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046348 Approved Approved Cytosol Mixed parathyroid gland: 16.6 -ARFIP1 HSU52521 ENSG00000164144 ADP-ribosylation factor interacting protein 1 4 152687727-152918463 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005080, HPA037375, HPA063759 Supported Supported Nucleus
Golgi apparatus
Vesicles Expressed in all endometrium: 39.0 -ICE1 KIAA0947 ENSG00000164151 Interactor of little elongation complex ELL subunit 1 5 5420664-5490234 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054452, HPA061934 Uncertain Supported Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 27.7 -HHIP FLJ20992, HIP ENSG00000164161 Hedgehog interacting protein 4 144646021-144745271 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012616 Uncertain Approved Nucleoplasm Tissue enhanced 0 lung: 24.3 cerebral cortex: 10.8 -ANAPC10 APC10, DKFZP564L0562, DOC1 ENSG00000164162 Anaphase promoting complex subunit 10 4 144967112-145098541 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044547 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all testis: 35.3 -ABCE1 OABP, RLI, RNASEL1, RNASELI, RNS4I ENSG00000164163 ATP-binding cassette, sub-family E (OABP), member 1 4 145097932-145129179 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012476, HPA036846 Approved Validated Cytosol Expressed in all testis: 45.9 -OTUD4 DUBA6, HSHIN1, KIAA1046 ENSG00000164164 OTU deubiquitinase 4 4 145110838-145180161 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036623 Uncertain Approved Cytosol Expressed in all testis: 72.6 -LSM6 YDR378C ENSG00000164167 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated 4 146175685-146200000 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045079 Approved Approved Actin filaments Expressed in all lymph node: 42.6 -TMEM184C FLJ10846, TMEM34 ENSG00000164168 Transmembrane protein 184C 4 147617383-147672044 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA054013 Uncertain Approved Nucleoplasm
Vesicles Group enriched 5 parathyroid gland: 253.7;thyroid gland: 54.5 placenta: 28.5 -PRMT9 FLJ46629, PRMT10 ENSG00000164169 Protein arginine methyltransferase 9 4 147637785-147684230 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036844, HPA042537 Uncertain Approved Nucleoplasm
Microtubules
Cytosol Mixed parathyroid gland: 14.5 -ITGA2 CD49B ENSG00000164171 Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 5 52989326-53094779 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017690, HPA060991, HPA063556 Supported Approved Nucleus
Cytosol Mixed parathyroid gland: 24.3 -MOCS2 MOCO1 ENSG00000164172 Molybdenum cofactor synthesis 2 5 53095679-53110063 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037679, HPA037680 Approved Approved Nucleus
Cytosol Expressed in all kidney: 106.8 -SLC45A2 AIM-1, MATP, OCA4 ENSG00000164175 Solute carrier family 45, member 2 5 33944616-33984730 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 1.2;testis: 1.3 prostate: 0.3 -EDIL3 DEL1 ENSG00000164176 EGF-like repeats and discoidin I-like domains 3 5 83940554-84384793 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020415 Approved Tissue enhanced 0 cerebral cortex: 131.9 gallbladder: 54.2 -TMEM161B MGC33214 ENSG00000164180 Transmembrane protein 161B 5 88189633-88269476 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044562 Uncertain Expressed in all parathyroid gland: 58.9 -ELOVL7 FLJ23563 ENSG00000164181 ELOVL fatty acid elongase 7 5 60751791-60844389 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036337 Approved Mixed prostate: 36.3 -NDUFAF2 B17.2L, mimitin, MMTN, NDUFA12L ENSG00000164182 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 5 60945129-61153037 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048082, HPA054776 Supported Validated Mitochondria Expressed in all adrenal gland: 48.2 -ZNF474 4933409D10Rik, FLJ32921 ENSG00000164185 Zinc finger protein 474 5 122129513-122179617 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036595 Uncertain Group enriched 8 fallopian tube: 26.3;testis: 13.5 lung: 2.6 -LMBRD2 DKFZp434H2226 ENSG00000164187 LMBR1 domain containing 2 5 36098412-36151961 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012165 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 25.5 -RANBP3L FLJ25422 ENSG00000164188 RAN binding protein 3-like 5 36248434-36302114 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037471, HPA037472, HPA061526 Approved Uncertain Nucleoplasm Tissue enhanced 0 cerebral cortex: 31.1;kidney: 28.5;prostate: 21.7 breast: 10.0 -NIPBL DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2 ENSG00000164190 Nipped-B homolog (Drosophila) 5 36876759-37066413 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040834, HPA058239 Approved Supported Nucleoplasm
Vesicles Expressed in all parathyroid gland: 55.9 -RNF180 ENSG00000164197 Ring finger protein 180 5 64165844-64372869 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA006897 Approved Approved Cytosol Tissue enhanced 0 parathyroid gland: 62.3 thyroid gland: 24.9 -ADGRV1 DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1 ENSG00000164199 Adhesion G protein-coupled receptor V1 5 90529344-91164221 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067503 Approved Group enriched 6 adrenal gland: 56.5;cerebral cortex: 29.1 thyroid gland: 6.6 -SLC25A46 ENSG00000164209 Solute carrier family 25, member 46 5 110738136-110765161 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039601, HPA071582 Approved Supported Mitochondria Expressed in all testis: 37.3 -STARD4 ENSG00000164211 StAR-related lipid transfer (START) domain containing 4 5 111496033-111512590 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046177, HPA048081 Approved Approved Plasma membrane Mixed duodenum: 42.6 -PGGT1B BGGI, GGTI ENSG00000164219 Protein geranylgeranyltransferase type I, beta subunit 5 115204012-115262872 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030646 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Cytosol Expressed in all parathyroid gland: 18.6 -F2RL2 PAR3 ENSG00000164220 Coagulation factor II (thrombin) receptor-like 2 5 76615482-76623434 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 gallbladder: 10.9 smooth muscle: 5.6 -CCDC112 MGC39633 ENSG00000164221 Coiled-coil domain containing 112 5 115267188-115296831 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045120, HPA050621 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Tissue enriched 6 testis: 73.4 cerebral cortex: 13.2 -ANKRD33B ENSG00000164236 Ankyrin repeat domain 33B 5 10564330-10657816 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA056974 Uncertain Approved Mitochondria Mixed cerebral cortex: 12.9 -CMBL FLJ23617 ENSG00000164237 Carboxymethylenebutenolidase homolog (Pseudomonas) 5 10275875-10308026 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036571 Uncertain Expressed in all kidney: 313.7 -C5orf63 FLJ44606, YDR286C ENSG00000164241 Chromosome 5 open reading frame 63 5 127042558-127073492 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043240 Approved Approved Mitochondria Mixed cerebral cortex: 36.9 -PRRC1 FLJ32875 ENSG00000164244 Proline-rich coiled-coil 1 5 127517609-127555089 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039212 Approved Approved Vesicles Expressed in all parathyroid gland: 53.1 -F2RL1 GPR11, PAR2 ENSG00000164251 Coagulation factor II (thrombin) receptor-like 1 5 76818933-76835315 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB012989, HPA014091 Approved Approved Plasma membrane Mixed colon: 59.9 -AGGF1 FLJ10283, GPATC7, GPATCH7, HSU84971, VG5Q ENSG00000164252 Angiogenic factor with G patch and FHA domains 1 5 77029251-77065234 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043500 Uncertain Expressed in all testis: 33.7 -WDR41 FLJ10904 ENSG00000164253 WD repeat domain 41 5 77425970-77620611 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043124 Approved Approved Nucleus
Golgi apparatus
Cytosol Expressed in all testis: 51.4 -PRDM9 MSBP3, PFM6, ZNF899 ENSG00000164256 PR domain containing 9 5 23443586-23528597 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA059555 Uncertain Group enriched 10 epididymis: 4.3;testis: 7.7 bone marrow: 0.6 -NDUFS4 AQDQ, CI-18 ENSG00000164258 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 5 53560633-53683340 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003884 Supported Supported Mitochondria Expressed in all kidney: 138.5 -SCGB3A2 LU103, PNSP1, UGRP1 ENSG00000164265 Secretoglobin, family 3A, member 2 5 147870682-147882191 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 187 lung: 1862.5 thyroid gland: 9.9 -SPINK1 PCTT, PSTI, Spink3, TATI ENSG00000164266 Serine peptidase inhibitor, Kazal type 1 5 147824568-147831786 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026366, HPA027498 Supported Tissue enriched 8 pancreas: 7130.5 stomach: 935.1 -HTR4 5-HT4 ENSG00000164270 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 5 148451032-148677235 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040591 Approved Tissue enhanced 0 duodenum: 5.0;small intestine: 10.2 heart muscle: 3.5 -ESM1 ENSG00000164283 Endothelial cell-specific molecule 1 5 54977864-55022671 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 kidney: 19.1;thyroid gland: 27.2 endometrium: 5.7 -GRPEL2 DKFZp451C205, FLJ23713, Mt-GrpE#2 ENSG00000164284 GrpE-like 2, mitochondrial (E. coli) 5 149345430-149354583 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018173, HPA023211 Uncertain Validated Mitochondria Tissue enhanced 0 esophagus: 30.5 tonsil: 9.7 -CDC20B FLJ37927 ENSG00000164287 Cell division cycle 20B 5 55112995-55173175 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053900 Uncertain Group enriched 6 endometrium: 1.2;fallopian tube: 3.4;kidney: 1.2;testis: 4.7 lung: 0.4 -ARSK DKFZp313G1735, TSULF ENSG00000164291 Arylsulfatase family, member K 5 95555074-95605064 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042384 Approved Approved Nucleus
Vesicles Mixed parathyroid gland: 22.5 -RHOBTB3 KIAA0878 ENSG00000164292 Rho-related BTB domain containing 3 5 95713522-95824383 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000265 Uncertain Vesicles Expressed in all ovary: 98.7 -GPX8 EPLA847, UNQ847 ENSG00000164294 Glutathione peroxidase 8 (putative) 5 55160118-55167071 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036720, HPA036721 Supported Supported Actin filaments
Cytosol Mixed cervix: 47.7 -TIGD6 DKFZp761E2110 ENSG00000164296 Tigger transposable element derived 6 5 149993118-150001167 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044599 Uncertain Approved Nucleoplasm
Vesicles
Actin filaments Tissue enhanced 0 parathyroid gland: 21.1 testis: 6.7 -SPZ1 FLJ25709, NYD-TSP1, PPP1R148 ENSG00000164299 Spermatogenic leucine zipper 1 5 80319625-80321842 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 170 testis: 45.0 epididymis: 0.2 -SERINC5 C5orf12, TPO1 ENSG00000164300 Serine incorporator 5 5 80111651-80256079 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037898, HPA037899 Supported Uncertain Nucleus
Golgi apparatus
Vesicles Mixed testis: 55.9 -ENPP6 MGC33971 ENSG00000164303 Ectonucleotide pyrophosphatase/phosphodiesterase 6 4 184088706-184221230 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042740 Approved Uncertain Golgi apparatus Tissue enhanced 0 kidney: 30.5;ovary: 15.0 cerebral cortex: 8.7 -CAGE1 bA69L16.7, CT95, CTAG3 ENSG00000164304 Cancer antigen 1 6 7326656-7389743 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029832 Uncertain Tissue enriched 82 testis: 8.2 bone marrow: 0.1 -CASP3 apopain, CPP32, CPP32B, Yama ENSG00000164305 Caspase 3, apoptosis-related cysteine peptidase 4 184627696-184649509 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000091, HPA002643, CAB008381 Approved Supported Nucleoplasm
Mitochondria Expressed in all duodenum: 55.9 -PRIMPOL CCDC111, FLJ33167 ENSG00000164306 Primase and polymerase (DNA-directed) 4 184649613-184694963 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054372 Uncertain Approved Nucleoplasm
Cytosol Mixed endometrium: 17.1 -ERAP1 A-LAP, ARTS-1, ERAAP1, KIAA0525, PILS-AP ENSG00000164307 Endoplasmic reticulum aminopeptidase 1 5 96760810-96808100 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025095, HPA042317 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all placenta: 68.5 -ERAP2 L-RAP, LRAP ENSG00000164308 Endoplasmic reticulum aminopeptidase 2 5 96875939-96919716 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025618, HPA034498 Supported Uncertain Mitochondria Mixed lymph node: 50.0 -CMYA5 C5orf10, DKFZp451G223, myospryn, SPRYD2, TRIM76 ENSG00000164309 Cardiomyopathy associated 5 5 79689877-79800240 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 8 heart muscle: 108.8;skeletal muscle: 172.4 ovary: 18.1 -EGFLAM AGRINL, AGRNL, FLJ39155, PIKA ENSG00000164318 EGF-like, fibronectin type III and laminin G domains 5 38258409-38465021 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 placenta: 72.7 adipose tissue: 42.8 -CFAP97 DKFZp434F1728, hmw, KIAA1430 ENSG00000164323 Cilia and flagella associated protein 97 4 185159665-185209504 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049446, HPA053335 Approved Supported Nucleoli
Plasma membrane
Cytosol Expressed in all testis: 67.5 -TMEM174 FLJ31268, MGC13034 ENSG00000164325 Transmembrane protein 174 5 73173195-73175143 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA037975 Supported Tissue enriched 685 kidney: 158.0 thyroid gland: 0.2 -CARTPT CART ENSG00000164326 CART prepropeptide 5 71719163-71721048 FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046278 Uncertain Tissue enriched 8 adrenal gland: 133.2 cerebral cortex: 17.4 -RICTOR AVO3, KIAA1999, MGC39830, PIA ENSG00000164327 RPTOR independent companion of MTOR, complex 2 5 38937919-39074408 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037802, HPA037803 Approved Approved Mitochondria Expressed in all testis: 17.2 -PAPD4 FLJ38499, GLD2, TUT2 ENSG00000164329 PAP associated domain containing 4 5 79612120-79686648 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054468 Approved Cytosol Expressed in all spleen: 38.9 -EBF1 EBF, OLF1 ENSG00000164330 Early B-cell factor 1 5 158695916-159099761 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061169 Approved Nucleoplasm
Vesicles Tissue enhanced 0 adipose tissue: 41.6 placenta: 16.6 -ANKRA2 ENSG00000164331 Ankyrin repeat, family A (RFXANK-like), 2 5 73552335-73565686 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA065263 Approved Plasma membrane
Cell Junctions Expressed in all thyroid gland: 26.1 -UBLCP1 CPUB1, MGC10067 ENSG00000164332 Ubiquitin-like domain containing CTD phosphatase 1 5 159263081-159286040 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039615 Approved Validated Nucleus
Nucleoli Expressed in all testis: 49.8 -FAM170A ENSG00000164334 Family with sequence similarity 170, member A 5 119629559-119635822 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037900, HPA037901, HPA037902 Approved Tissue enriched 103 testis: 20.8 skin: 0.2 -UTP15 FLJ12787, FLJ23637, NET21 ENSG00000164338 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) 5 73565443-73583377 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044697 Supported Nucleoli
Endoplasmic reticulum Expressed in all bone marrow: 23.2 -TLR3 CD283 ENSG00000164342 Toll-like receptor 3 4 186069152-186088069 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025658 Approved Mixed placenta: 24.3 -KLKB1 KLK3 ENSG00000164344 Kallikrein B, plasma (Fletcher factor) 1 4 186208979-186258471 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 45 liver: 154.2 kidney: 3.4 -NSA2 FLJ94393, HCLG1, HUSSY-29, TINP1 ENSG00000164346 NSA2 ribosome biogenesis homolog 5 74766991-74780113 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043487 Approved Supported Nucleus
Nucleoli Expressed in all ovary: 74.4 -GFM2 EFG2, FLJ21661 ENSG00000164347 G elongation factor, mitochondrial 2 5 74721204-74767371 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036863 Uncertain Expressed in all fallopian tube: 36.3 -TERT EST2, hEST2, TCS1, TP2, TRT ENSG00000164362 Telomerase reverse transcriptase 5 1253147-1295069 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054641, HPA065897 Validated Nucleoplasm Not detected testis: 0.5 -SLC6A18 FLJ31236, Xtrp2 ENSG00000164363 Solute carrier family 6 (neutral amino acid transporter), member 18 5 1225355-1246189 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA011885 Supported Tissue enriched 83 kidney: 8.2 epididymis: 0.0 -CCDC127 FLJ25701 ENSG00000164366 Coiled-coil domain containing 127 5 196871-218215 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045052 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all thyroid gland: 25.8 -FOXQ1 HFH1 ENSG00000164379 Forkhead box Q1 6 1312473-1314187 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA059700 Supported Nucleus Tissue enhanced 0 stomach: 102.1;urinary bladder: 41.0 skin: 28.3 -ADGRF2 GPR111, hGPCR35, PGR20 ENSG00000164393 Adhesion G protein-coupled receptor F2 6 47656436-47697797 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035507 Uncertain Tissue enhanced 0 fallopian tube: 1.5;skin: 1.4 esophagus: 0.3 -ACSL6 ACS2, FACL6, KIAA0837, LACS2, LACS5 ENSG00000164398 Acyl-CoA synthetase long-chain family member 6 5 131949973-132012243 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040470 Uncertain Group enriched 6 bone marrow: 18.0;cerebral cortex: 62.1;parathyroid gland: 22.1;seminal vesicle: 28.7;testis: 51.2 adrenal gland: 6.5 -IL3 IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF ENSG00000164399 Interleukin 3 5 132060529-132063204 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Not detected testis: 0.3 -CSF2 GM-CSF, GMCSF ENSG00000164400 Colony stimulating factor 2 (granulocyte-macrophage) 5 132073790-132076170 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA057404, HPA062006 Validated Vesicles Tissue enhanced 0 lung: 3.0 urinary bladder: 0.9 -SEPT8 KIAA0202, SEP2 ENSG00000164402 Septin 8 5 132750817-132807241 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005665, HPA036534 Approved Uncertain Actin filaments
Cytosol Expressed in all cerebral cortex: 281.0 -SHROOM1 APXL2, KIAA1960 ENSG00000164403 Shroom family member 1 5 132822141-132830898 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037690, HPA037691 Uncertain Uncertain Vesicles Tissue enhanced 0 prostate: 50.3 seminal vesicle: 21.1 -GDF9 ENSG00000164404 Growth differentiation factor 9 5 132861181-132866884 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA069146 Supported Group enriched 5 epididymis: 4.9;testis: 14.0 thyroid gland: 1.8 -UQCRQ QCR8, QP-C, UQCR7 ENSG00000164405 Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 5 132866560-132868031 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046693, HPA053323 Approved Validated Mitochondria Expressed in all skeletal muscle: 376.1 -LEAP2 LEAP-2 ENSG00000164406 Liver expressed antimicrobial peptide 2 5 132872322-132875046 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035750 Uncertain Tissue enriched 8 liver: 66.2 small intestine: 7.8 -GJB7 bA136M9.1, CX25 ENSG00000164411 Gap junction protein, beta 7, 25kDa 6 87282978-87329278 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 11.1;placenta: 3.8 testis: 1.5 -SLC35A1 CMPST, hCST ENSG00000164414 Solute carrier family 35 (CMP-sialic acid transporter), member A1 6 87470623-87512336 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Expressed in all prostate: 59.9 -GRIK2 GluK2, GLUR6, MRT6 ENSG00000164418 Glutamate receptor, ionotropic, kainate 2 6 101398788-102070083 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014395, HPA014623, CAB022463 Approved Tissue enhanced 0 cerebral cortex: 22.6 thyroid gland: 6.2 -MB21D1 C6orf150 ENSG00000164430 Mab-21 domain containing 1 6 73413515-73452276 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031700, HPA031702 Supported Approved Microtubule organizing center
Cytosol Mixed bone marrow: 8.7 -FABP7 B-FABP, BLBP ENSG00000164434 Fatty acid binding protein 7, brain 6 122779475-122784074 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025488, HPA028825, CAB058697 Supported Supported Nucleoplasm
Cytosol Group enriched 13 breast: 32.9;cerebral cortex: 102.5 skin: 5.2 -TLX3 HOX11L2, RNX ENSG00000164438 T-cell leukemia homeobox 3 5 171309284-171312134 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA074512 Approved Nucleoplasm
Centrosome Not detected epididymis: 0.0 -TXLNB C6orf198, dJ522B19.2, DKFZp451A175, MDP77 ENSG00000164440 Taxilin beta 6 139240061-139292139 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030401, HPA030402, HPA030403 Supported Group enriched 6 heart muscle: 51.0;skeletal muscle: 102.3 ovary: 13.7 -CITED2 MRG1 ENSG00000164442 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 6 139371807-139374620 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016157, CAB069879 Supported Supported Nucleoplasm Expressed in all thyroid gland: 376.7 -FAM26D C6orf78, FLJ32239 ENSG00000164451 Family with sequence similarity 26, member D 6 116529013-116558868 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 46 placenta: 33.6 testis: 0.7 -T ENSG00000164458 T brachyury transcription factor 6 166157656-166168700 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003322 Uncertain Supported Nucleus Tissue enriched 23 parathyroid gland: 9.8 testis: 0.4 -CREBRF C5orf41, LRF ENSG00000164463 CREB3 regulatory factor 5 173056352-173139284 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015329 Supported Nucleus Expressed in all bone marrow: 43.7 -DCBLD1 dJ94G16.1, MGC46341 ENSG00000164465 Discoidin, CUB and LCCL domain containing 1 6 117453817-117569858 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059667 Approved Approved Cytosol Mixed gallbladder: 14.4 -SFXN1 FLJ12876 ENSG00000164466 Sideroflexin 1 5 175477062-175529742 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019543, HPA063745 Uncertain Validated Mitochondria Expressed in all liver: 51.5 -SAMD3 bA73O6.2, FLJ34032 ENSG00000164483 Sterile alpha motif domain containing 3 6 130144315-130365425 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028992, HPA028993 Uncertain Tissue enhanced 0 spleen: 13.3 lymph node: 11.7 -TMEM200A KIAA1913, TTMC ENSG00000164484 Transmembrane protein 200A 6 130365734-130443063 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014396 Uncertain Tissue enhanced 0 endometrium: 64.8 smooth muscle: 29.0 -IL22RA2 CRF2-S1, IL-22BP ENSG00000164485 Interleukin 22 receptor, alpha 2 6 137143820-137173648 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA030582, CAB034906 Uncertain Tissue enhanced 0 breast: 4.2;tonsil: 3.0 appendix: 1.9 -DACT2 bA503C24.7, C6orf116, DAPPER2 ENSG00000164488 Dishevelled-binding antagonist of beta-catenin 2 6 168292830-168319754 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030251, HPA030252 Approved Tissue enhanced 0 placenta: 18.7 prostate: 6.7 -PDSS2 bA59I9.3, C6orf210 ENSG00000164494 Prenyl (decaprenyl) diphosphate synthase, subunit 2 6 107152557-107459564 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029685, HPA029686 Approved Validated Cytosol Expressed in all prostate: 23.6 -C7orf72 ENSG00000164500 Chromosome 7 open reading frame 72 7 50096036-50159830 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA026094 Uncertain Tissue enriched 30 testis: 5.8 tonsil: 0.1 -STXBP5 LLGL3, tomosyn ENSG00000164506 Syntaxin binding protein 5 (tomosyn) 6 147204425-147390476 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039991, HPA049727 Validated Cytosol Tissue enriched 7 parathyroid gland: 273.3 testis: 40.1 -HIST1H2AA bA317E16.2, H2AFR ENSG00000164508 Histone cluster 1, H2aa 6 25726132-25726527 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enriched 91 testis: 17.0 kidney: 0.1 -IL31RA CRL, CRL3, GLM-R, Glmr, IL-31RA ENSG00000164509 Interleukin 31 receptor A 5 55851379-55922853 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051532 Approved Nucleoplasm
Vesicles Tissue enhanced 0 testis: 3.7 bone marrow: 1.2 -ANKRD55 FLJ11795 ENSG00000164512 Ankyrin repeat domain 55 5 56099678-56233359 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051049 Approved Group enriched 5 lymph node: 4.2;testis: 17.2 tonsil: 1.9 -RAET1E bA350J20.7, LETAL, ULBP4 ENSG00000164520 Retinoic acid early transcript 1E 6 149883375-149898102 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054022 Approved Focal adhesion sites
Cytosol Tissue enhanced 0 esophagus: 71.1;skin: 29.0 tonsil: 10.8 -PI16 CD364, dJ90K10.5, MGC45378, MSMBBP ENSG00000164530 Peptidase inhibitor 16 6 36948263-36964837 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043763 Uncertain Tissue enhanced 0 cervix, uterine: 198.3 urinary bladder: 81.1 -TBX20 ENSG00000164532 T-box 20 7 35202430-35254147 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 heart muscle: 26.9 adrenal gland: 5.7 -DAGLB DAGLBETA, KCCR13L ENSG00000164535 Diacylglycerol lipase, beta 7 6409126-6484190 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069377 Supported Plasma membrane Expressed in all cerebral cortex: 20.6 -KIAA0895 ENSG00000164542 KIAA0895 7 36324221-36390125 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA020512, HPA021036, HPA061066 Uncertain Approved Nucleus
Plasma membrane
Cell Junctions
Cytosol Tissue enhanced 0 testis: 43.8 parathyroid gland: 23.4 -STK17A DRAK1 ENSG00000164543 Serine/threonine kinase 17a 7 43582758-43626786 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018138, HPA037979 Uncertain Approved Nuclear speckles
Plasma membrane Expressed in all lymph node: 49.9 -TRA2A AWMS1, htra-2-alpha, tra2a ENSG00000164548 Transformer 2 alpha homolog (Drosophila) 7 23504780-23532041 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054018 Uncertain Supported Nucleoli
Vesicles Expressed in all bone marrow: 65.5 -GALNT10 GalNAc-T10 ENSG00000164574 Polypeptide N-acetylgalactosaminyltransferase 10 5 154190730-154420984 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007525 Approved Approved Nucleoplasm
Golgi apparatus
Plasma membrane Expressed in all ovary: 81.4 -SAP30L FLJ11526, NS4ATP2 ENSG00000164576 SAP30-like 5 154445957-154461054 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048665 Supported Nucleus
Nucleoli Mixed parathyroid gland: 24.7 -RPS14 EMTB, S14 ENSG00000164587 Ribosomal protein S14 5 150443190-150449756 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018504 Uncertain Validated Endoplasmic reticulum
Cytosol Expressed in all fallopian tube: 1979.7 -HCN1 BCNG-1, BCNG1, HAC-2 ENSG00000164588 Hyperpolarization activated cyclic nucleotide gated potassium channel 1 5 45254950-45696498 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019195 Supported Tissue enriched 7 cerebral cortex: 11.5 heart muscle: 1.7 -MYOZ3 CS-3, CS3, FRP3 ENSG00000164591 Myozenin 3 5 150660874-150679365 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039166 Supported Tissue enriched 11 skeletal muscle: 87.7 testis: 7.9 -COG5 GOLTC1, GTC90 ENSG00000164597 Component of oligomeric golgi complex 5 7 107201555-107564514 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020300, HPA041583 Uncertain Validated Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 46.1 -NEUROD6 Atoh2, bHLHa2, Math-2, Nex1, NEX1M ENSG00000164600 Neuronal differentiation 6 7 31337461-31340894 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027046 Approved Tissue enriched 225 cerebral cortex: 22.4 epididymis: 0.0 -C7orf60 DKFZp762M126, FLJ31818 ENSG00000164603 Chromosome 7 open reading frame 60 7 112819147-112939916 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044405, HPA050733 Uncertain Approved Cytosol Mixed testis: 14.8 -GPR85 SREB2 ENSG00000164604 G protein-coupled receptor 85 7 113078331-113087778 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 16.8 skeletal muscle: 11.5 -SLU7 9G8 ENSG00000164609 SLU7 homolog, splicing factor 5 160401641-160421711 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035907, HPA058120 Uncertain Validated Nucleoplasm
Nuclear speckles Expressed in all cerebral cortex: 50.3 -RP9 PAP-1 ENSG00000164610 Retinitis pigmentosa 9 (autosomal dominant) 7 33094797-33109401 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031523, HPA050778 Uncertain Supported Nucleus
Cytosol Expressed in all testis: 29.2 -PTTG1 EAP1, HPTTG, PTTG, securin, TUTR1 ENSG00000164611 Pituitary tumor-transforming 1 5 160421822-160428744 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008373, HPA008890, HPA045034 Supported Supported Nucleoli
Cytosol Tissue enhanced 0 testis: 284.3 tonsil: 125.0 -CAMLG CAML, GET2 ENSG00000164615 Calcium modulating ligand 5 134738501-134752160 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052636, HPA056472 Approved Approved Nucleus
Nucleoli
Vesicles Expressed in all testis: 99.0 -BMPER CRIM3, Cv2 ENSG00000164619 BMP binding endothelial regulator 7 33904911-34155872 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA018083 Uncertain Supported Mixed placenta: 9.4 -RELL2 C5orf16, FLJ90583 ENSG00000164620 RELT-like 2 5 141636950-141641077 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077928 Uncertain Vesicles Tissue enhanced 0 cerebral cortex: 13.2;parathyroid gland: 20.4 testis: 4.2 -KCNK5 K2p5.1, TASK-2 ENSG00000164626 Potassium channel, two pore domain subfamily K, member 5 6 39188973-39229450 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059148 Uncertain Approved Nucleus Tissue enhanced 0 small intestine: 40.1 gallbladder: 29.6 -KIF6 C6orf102, dJ1043E3.1, dJ137F1.4, dJ188D3.1, DKFZp451I2418, MGC33317 ENSG00000164627 Kinesin family member 6 6 39329990-39725405 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038811, HPA058624 Supported Approved Centrosome Group enriched 6 cerebral cortex: 7.1;fallopian tube: 6.0;testis: 9.7 lung: 1.2 -ZNF12 GIOT-3, KOX3, ZNF325 ENSG00000164631 Zinc finger protein 12 7 6688433-6706923 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063402 Supported Nucleoplasm
Centrosome Expressed in all parathyroid gland: 30.7 -SLC29A4 ENT4, FLJ34923 ENSG00000164638 Solute carrier family 29 (equilibrative nucleoside transporter), member 4 7 5274369-5306870 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA052829 Supported Microtubules
Cytokinetic bridge Tissue enhanced 0 adipose tissue: 44.2 cerebral cortex: 12.0 -C7orf62 MGC26647 ENSG00000164645 Chromosome 7 open reading frame 62 7 88794106-88795721 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023817, HPA024163 Uncertain Nucleoplasm
Mitochondria Tissue enriched 458 testis: 51.4 thyroid gland: 0.1 -STEAP1 PRSS24, STEAP ENSG00000164647 Six transmembrane epithelial antigen of the prostate 1 7 90154375-90164829 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030985 Uncertain Tissue enhanced 0 prostate: 124.2 appendix: 41.5 -CDCA7L JPO2, R1, RAM2 ENSG00000164649 Cell division cycle associated 7-like 7 21900900-21946084 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027169 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all thyroid gland: 45.8 -SP8 ENSG00000164651 Sp8 transcription factor 7 20782283-20786886 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA054006 Uncertain Approved Nucleus Tissue enriched 12 prostate: 9.8 skin: 0.8 -MIOS FLJ20323 ENSG00000164654 Missing oocyte, meiosis regulator, homolog (Drosophila) 7 7566872-7608929 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042928, HPA052223 Approved Validated Nucleoplasm
Cytosol Expressed in all parathyroid gland: 53.8 -KIAA1324L EIG121L, FLJ31340 ENSG00000164659 KIAA1324-like 7 86876906-87059699 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044527, HPA076093 Uncertain Approved Endoplasmic reticulum Tissue enhanced 0 lung: 32.3 cerebral cortex: 21.8 -USP49 MGC20741 ENSG00000164663 Ubiquitin specific peptidase 49 6 41789896-41895361 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA030254, HPA030255 Uncertain Mixed testis: 9.4 -SYTL3 exophilin-6, SLP3 ENSG00000164674 Synaptotagmin-like 3 6 158650014-158764876 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030584, HPA030585, HPA030586 Approved Approved Nucleoli fibrillar center
Vesicles Tissue enhanced 0 thyroid gland: 44.4 fallopian tube: 22.6 -IQUB FLJ35834 ENSG00000164675 IQ motif and ubiquitin domain containing 7 123452400-123535077 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 8 testis: 65.9 fallopian tube: 8.1 -HEY1 bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1 ENSG00000164683 Hes-related family bHLH transcription factor with YRPW motif 1 8 79764010-79767863 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA055599, HPA063472 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Tissue enhanced 0 cerebral cortex: 96.6 placenta: 28.7 -ZNF704 FLJ16218, Gig1 ENSG00000164684 Zinc finger protein 704 8 80628451-80874781 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024285, HPA024302 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 35.0 -FABP5 E-FABP, KFABP, PA-FABP ENSG00000164687 Fatty acid binding protein 5 (psoriasis-associated) 8 81280363-81284777 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017831, CAB040577, HPA051895 Supported Supported Plasma membrane
Cytosol Expressed in all esophagus: 1671.2 -SHH HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS ENSG00000164690 Sonic hedgehog 7 155799986-155812273 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adrenal gland: 12.0;stomach: 10.7;urinary bladder: 14.0 cervix: 6.7 -TAGAP ARHGAP47, FLJ32631, IDDM21 ENSG00000164691 T-cell activation RhoGTPase activating protein 6 159034468-159045152 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031000 Uncertain Tissue enhanced 0 bone marrow: 130.1 lymph node: 56.2 -COL1A2 OI4 ENSG00000164692 Collagen, type I, alpha 2 7 94394561-94431232 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032650, HPA059738 Approved Supported Endoplasmic reticulum Expressed in all cervix: 2933.7 -FNDC1 bA243O10.1, dJ322A24.1, FNDC2, KIAA1866 ENSG00000164694 Fibronectin type III domain containing 1 6 159169397-159272109 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030962, HPA030963 Approved Supported Nuclear speckles Tissue enhanced 0 gallbladder: 23.0;thyroid gland: 33.8 smooth muscle: 16.3 -CHMP4C MGC22825, Shax3, VPS32C ENSG00000164695 Charged multivesicular body protein 4C 8 81732434-81759515 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023799 Approved Mixed duodenum: 42.9 -SLC13A4 SUT-1, SUT1 ENSG00000164707 Solute carrier family 13 (sodium/sulfate symporter), member 4 7 135681237-135729258 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048582 Approved Tissue enriched 10 placenta: 76.2 testis: 7.3 -PGAM2 PGAM-M ENSG00000164708 Phosphoglycerate mutase 2 (muscle) 7 44062727-44065587 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043801, HPA049237, HPA060173 Approved Uncertain Nucleus
Nucleoli
Cytosol Group enriched 8 heart muscle: 527.3;skeletal muscle: 1459.8 testis: 126.1 -BRI3 ENSG00000164713 Brain protein I3 7 98252379-98310441 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042215 Uncertain Expressed in all lung: 119.5 -LMTK2 AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100 ENSG00000164715 Lemur tyrosine kinase 2 7 98106885-98209633 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010657, HPA041836 Uncertain Approved Nuclear speckles
Plasma membrane
Microtubule organizing center
Cytosol Expressed in all cerebral cortex: 28.0 -SLC35G3 AMAC1, FLJ40154, TMEM21A ENSG00000164729 Solute carrier family 35, member G3 17 35192520-35194523 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 15 testis: 1.6 skeletal muscle: 0.1 -CTSB ENSG00000164733 Cathepsin B 8 11842524-11869448 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000457, HPA018156 Uncertain Supported Nucleoli
Vesicles Expressed in all thyroid gland: 2885.5 -SOX17 ENSG00000164736 SRY (sex determining region Y)-box 17 8 54457935-54460888 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025594, HPA068399 Supported Approved Nucleoplasm Tissue enhanced 0 cervix, uterine: 30.1;endometrium: 32.1;fallopian tube: 30.1 adipose tissue: 14.7 -DLC1 ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12 ENSG00000164741 DLC1 Rho GTPase activating protein 8 13083361-13604610 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017753 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all lung: 78.7 -ADCY1 AC1 ENSG00000164742 Adenylate cyclase 1 (brain) 7 45574140-45723116 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018364, HPA068274 Uncertain Approved Mitochondria Tissue enhanced 0 cerebral cortex: 35.1 cervix: 8.2 -C8orf48 FLJ25402 ENSG00000164743 Chromosome 8 open reading frame 48 8 13566843-13568287 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025068, HPA026107, HPA027431, HPA027440 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 12.3 thyroid gland: 7.2 -SUN3 MGC33329, SUNC1 ENSG00000164744 Sad1 and UNC84 domain containing 3 7 47987148-48029119 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008344 Approved Golgi apparatus Tissue enriched 153 testis: 74.2 placenta: 0.4 -C7orf57 ENSG00000164746 Chromosome 7 open reading frame 57 7 48035511-48061304 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA021286 Supported Tissue enhanced 0 fallopian tube: 21.7;testis: 6.8 lung: 3.4 -HNF4G NR2A2 ENSG00000164749 Hepatocyte nuclear factor 4, gamma 8 75407914-75566843 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005438, HPA010610 Supported Approved Nucleoplasm
Cytosol Group enriched 5 duodenum: 103.0;small intestine: 128.1 rectum: 21.4 -PEX2 PAF-1, PMP35, PXMP3, RNF72, ZWS3 ENSG00000164751 Peroxisomal biogenesis factor 2 8 76980258-77001044 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010983, HPA011410, HPA027729 Approved Supported Vesicles Expressed in all seminal vesicle: 111.4 -RAD21 hHR21, KIAA0078, SCC1 ENSG00000164754 RAD21 cohesin complex component 8 116845935-116874866 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020044, CAB022065 Supported Validated Nucleoplasm Expressed in all testis: 161.7 -SLC30A8 ENSG00000164756 Solute carrier family 30 (zinc transporter), member 8 8 116950273-117176714 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 pancreas: 13.2 salivary gland: 5.0 -MED30 THRAP6, TRAP25 ENSG00000164758 Mediator complex subunit 30 8 117520713-117540262 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045767 Approved Nucleoplasm Expressed in all bone marrow: 27.9 -TNFRSF11B OCIF, OPG, TR1 ENSG00000164761 Tumor necrosis factor receptor superfamily, member 11b 8 118923557-118952200 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 5 thyroid gland: 139.8 kidney: 25.5 -SBSPON C8orf84, RPESP ENSG00000164764 Somatomedin B and thrombospondin, type 1 domain containing 8 73064540-73124088 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029595, CAB034214, CAB034332 Uncertain Mixed prostate: 21.8 -PHKG1 PHKG ENSG00000164776 Phosphorylase kinase, gamma 1 (muscle) 7 56080283-56092996 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA012057 Supported Tissue enriched 7 skeletal muscle: 100.5 cerebral cortex: 14.3 -EN2 ENSG00000164778 Engrailed homeobox 2 7 155458129-155464831 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level CAB025088, HPA045646, HPA069809 Uncertain Supported Nucleus
Nucleoli fibrillar center Tissue enhanced 0 parathyroid gland: 1.9;testis: 1.1 endometrium: 0.6 -KCNV1 Kv8.1 ENSG00000164794 Potassium channel, voltage gated modifier subfamily V, member 1 8 109963645-109975847 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 23 cerebral cortex: 21.9 epididymis: 0.9 -CSMD3 ENSG00000164796 CUB and Sushi multiple domains 3 8 112222928-113437099 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029007 Uncertain Group enriched 7 cerebral cortex: 4.9;testis: 1.8 spleen: 0.4 -SPIDR KIAA0146 ENSG00000164808 Scaffolding protein involved in DNA repair 8 47260575-47736306 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA027201, HPA041582 Approved Supported Nucleoplasm Expressed in all placenta: 32.4 -ORC5 ORC5L, Orc5p, ORC5T, PPP1R117 ENSG00000164815 Origin recognition complex, subunit 5 7 104126341-104208047 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019730 Approved Supported Nucleus
Cytosol Expressed in all testis: 34.2 -DEFA5 DEF5, HD-5 ENSG00000164816 Defensin, alpha 5, Paneth cell-specific 8 7055304-7056734 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015775, CAB069919 Supported Group enriched 462 duodenum: 10985.4;small intestine: 19506.1 appendix: 33.0 -DNAAF5 CILD18, FLJ20397, FLJ25564, FLJ31671, FLJ39381, HEATR2 ENSG00000164818 Dynein, axonemal, assembly factor 5 7 726701-786475 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020243 Uncertain Approved Nucleoplasm
Cytosol Expressed in all fallopian tube: 22.6 -DEFA4 DEF4, HP-4 ENSG00000164821 Defensin, alpha 4, corticostatin 8 6935822-6938338 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051266 Supported Tissue enriched 633 bone marrow: 3114.1 spleen: 4.9 -DEFA6 DEF6, HD-6 ENSG00000164822 Defensin, alpha 6, Paneth cell-specific 8 6924693-6926076 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019462 Supported Group enriched 521 duodenum: 5909.3;small intestine: 10744.7 colon: 15.9 -OSGIN2 C8orf1, hT41 ENSG00000164823 Oxidative stress induced growth inhibitor family member 2 8 89901859-89927888 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028515, HPA050595 Approved Approved Nucleoli Expressed in all parathyroid gland: 88.4 -DEFB1 BD1, DEFB-1, DEFB101, HBD-1, HBD1, MGC51822 ENSG00000164825 Defensin, beta 1 8 6870575-6878022 Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cervix, uterine: 614.0;kidney: 1487.1 salivary gland: 233.8 -SUN1 FLJ12407, KIAA0810, UNC84A ENSG00000164828 Sad1 and UNC84 domain containing 1 7 816615-896435 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008346, HPA008461 Supported Validated Nuclear membrane Expressed in all endometrium: 120.0 -OXR1 TLDC3 ENSG00000164830 Oxidation resistance 1 8 106270178-106752694 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027375, HPA027380, HPA027395 Supported Supported Vesicles Expressed in all cerebral cortex: 111.1 -TMEM74 FLJ30668, NET36 ENSG00000164841 Transmembrane protein 74 8 108606850-108787615 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA015672 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 6.3 testis: 1.5 -GPR146 PGR8 ENSG00000164849 G protein-coupled receptor 146 7 1044576-1059261 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all adipose tissue: 35.4 -GPER1 CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR ENSG00000164850 G protein-coupled estrogen receptor 1 7 1082208-1093815 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA027052 Approved Mixed placenta: 9.1 -UNCX Uncx4.1 ENSG00000164853 UNC homeobox 7 1232907-1237318 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA063294 Approved Nucleoplasm Not detected kidney: 0.4 -TMEM184A MGC9712 ENSG00000164855 Transmembrane protein 184A 7 1542235-1560821 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA053790, HPA071312 Uncertain Approved Nucleoplasm Tissue enhanced 0 skin: 33.5 esophagus: 26.7 -NOS3 ECNOS, eNOS ENSG00000164867 Nitric oxide synthase 3 (endothelial cell) 7 150990995-151014588 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002168 Supported Tissue enriched 7 spleen: 73.1 adipose tissue: 10.7 -SPAG11B EDDM2B, EP2, EP2C, EP2D, HE2 ENSG00000164871 Sperm associated antigen 11B 8 7442684-7463674 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 5396 epididymis: 6639.3 seminal vesicle: 1.2 -MICALL2 FLJ23471, JRAB, MGC46023, MICAL-L2 ENSG00000164877 MICAL-like 2 7 1428465-1459502 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025695 Approved Mixed small intestine: 17.8 -CA3 CAIII, Car3 ENSG00000164879 Carbonic anhydrase III 8 85373436-85449040 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004967, HPA021775, HPA026700 Supported Tissue enriched 16 skeletal muscle: 1839.1 prostate: 112.8 -INTS1 DKFZp586J0619, INT1, KIAA1440, NET28 ENSG00000164880 Integrator complex subunit 1 7 1470277-1504367 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021658, HPA053009 Approved Approved Nucleoplasm Expressed in all testis: 41.9 -CDK5 PSSALRE ENSG00000164885 Cyclin-dependent kinase 5 7 151053812-151058530 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008909, HPA018977, HPA064535 Approved Supported Nucleus
Plasma membrane
Cell Junctions
Cytosol Expressed in all cerebral cortex: 50.0 -SLC4A2 AE2, BND3L, EPB3L1, HKB3, NBND3 ENSG00000164889 Solute carrier family 4 (anion exchanger), member 2 7 151057210-151076527 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019339 Supported Approved Nuclear speckles
Plasma membrane
Cytosol Expressed in all parathyroid gland: 87.8 -SLC7A13 AGT-1, XAT2 ENSG00000164893 Solute carrier family 7 (anionic amino acid transporter), member 13 8 86214052-86321146 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 102 kidney: 42.6 testis: 0.4 -FASTK FAST ENSG00000164896 Fas-activated serine/threonine kinase 7 151076593-151080866 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031621, CAB032539 Approved Approved Nuclear speckles
Mitochondria Expressed in all skeletal muscle: 41.7 -TMUB1 C7orf21, SB144 ENSG00000164897 Transmembrane and ubiquitin-like domain containing 1 7 151081080-151083546 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029429 Approved Supported Nucleoplasm
Cytosol Expressed in all small intestine: 53.3 -C7orf55 FMC1, HSPC268 ENSG00000164898 Chromosome 7 open reading frame 55 7 139339457-139346319 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045663, HPA050553 Approved Approved Mitochondria Expressed in all thyroid gland: 12.2 -GBX1 ENSG00000164900 Gastrulation brain homeobox 1 7 151148589-151174745 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA055783 Uncertain Group enriched 57 skeletal muscle: 4.4;testis: 6.9 epididymis: 0.0 -PHAX FLJ13193, RNUXA ENSG00000164902 Phosphorylated adaptor for RNA export 5 126600268-126627252 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059630, HPA070326 Supported Validated Nucleoplasm Expressed in all cerebral cortex: 17.9 -ALDH7A1 ATQ1, EPD, PDE ENSG00000164904 Aldehyde dehydrogenase 7 family, member A1 5 126541841-126595418 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023296 Supported Supported Mitochondria
Cytosol Expressed in all kidney: 162.4 -FOXK1 IMAGE:5164497 ENSG00000164916 Forkhead box K1 7 4682309-4771443 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017998, HPA018864 Supported Supported Nucleoplasm
Nucleoli fibrillar center Mixed cerebral cortex: 12.4 -COX6C ENSG00000164919 Cytochrome c oxidase subunit VIc 8 99873200-99894062 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014295, CAB016244 Supported Validated Mitochondria Expressed in all duodenum: 349.0 -OSR2 FLJ90037 ENSG00000164920 Odd-skipped related transciption factor 2 8 98944403-98952104 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA052425, HPA063486 Uncertain Approved Nucleus
Plasma membrane Tissue enhanced 0 endometrium: 204.6;fallopian tube: 143.0 ovary: 102.5 -YWHAZ 14-3-3-zeta, KCIP-1, YWHAD ENSG00000164924 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 8 100916525-100953388 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005065 Approved Expressed in all esophagus: 928.6 -BAALC ENSG00000164929 Brain and acute leukemia, cytoplasmic 8 103140710-103230305 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA027132, HPA068307 Approved Supported Nucleus
Cytosol Tissue enriched 16 cerebral cortex: 248.4 adrenal gland: 15.7 -FZD6 Hfz6 ENSG00000164930 Frizzled class receptor 6 8 103298433-103332866 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017991 Approved Approved Plasma membrane Mixed parathyroid gland: 45.3 -CTHRC1 ENSG00000164932 Collagen triple helix repeat containing 1 8 103371515-103382997 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059806, HPA061896 Approved Approved Nucleoplasm Tissue enhanced 0 gallbladder: 138.2;placenta: 124.9;urinary bladder: 103.5 breast: 49.5 -SLC25A32 MFTC ENSG00000164933 Solute carrier family 25 (mitochondrial folate carrier), member 32 8 103398635-103415189 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024763, HPA047402 Uncertain Supported Mitochondria Expressed in all lymph node: 21.3 -DCAF13 DKFZP564O0463, Gm83, HSPC064, WDSOF1 ENSG00000164934 DDB1 and CUL4 associated factor 13 8 103414714-103443453 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044504 Uncertain Supported Nucleus
Nucleoli
Cell Junctions
Centrosome
Cytosol Expressed in all testis: 58.5 -DCSTAMP DC-STAMP, FIND, TM7SF4 ENSG00000164935 Dendrocyte expressed seven transmembrane protein 8 104339087-104356689 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 10 epididymis: 2.3;lung: 5.6 cervix: 0.4 -TP53INP1 DKFZp434M1317, FLJ22139, P53DINP1, SIP, Teap, TP53INP1A, TP53INP1B ENSG00000164938 Tumor protein p53 inducible nuclear protein 1 8 94925972-94949411 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA005856 Uncertain Supported Cytosol Expressed in all testis: 52.5 -INTS8 C8orf52, FLJ20530, INT8, MGC131633 ENSG00000164941 Integrator complex subunit 8 8 94813311-94881746 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057299 Approved Approved Nucleoplasm Expressed in all testis: 61.5 -KIAA1429 DKFZP434I116, fSAP121 ENSG00000164944 KIAA1429 8 94487693-94553529 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031530 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 30.0 -FREM1 C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR ENSG00000164946 FRAS1 related extracellular matrix 1 9 14734666-14910995 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 endometrium: 33.8;epididymis: 43.7 smooth muscle: 22.8 -GEM KIR ENSG00000164949 GTP binding protein overexpressed in skeletal muscle 8 94249253-94262350 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024798 Approved Tissue enhanced 0 gallbladder: 366.0 endometrium: 155.7 -PDP1 PDH, PDP, PPM2C ENSG00000164951 Pyruvate dehyrogenase phosphatase catalytic subunit 1 8 93857807-93926066 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018483, HPA019081, HPA021152 Uncertain Supported Nucleoplasm
Mitochondria
Cytosol Expressed in all adrenal gland: 82.7 -TMEM67 JBTS6, MGC26979, MKS3, NPHP11 ENSG00000164953 Transmembrane protein 67 8 93754844-93819234 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039940 Uncertain Tissue enhanced 0 fallopian tube: 21.9 testis: 12.8 -KIAA0196 SPG8 ENSG00000164961 KIAA0196 8 125024260-125091840 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034216, CAB034219, HPA064649, HPA070916 Supported Supported Nucleoplasm Expressed in all thyroid gland: 39.2 -RPP25L bA296L22.5, C9orf23, MGC29635 ENSG00000164967 Ribonuclease P/MRP 25kDa subunit-like 9 34610486-34612104 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052187, HPA059698 Uncertain Supported Nucleus Expressed in all skeletal muscle: 38.7 -FAM219A bA573M23.5, C9orf25, FLJ39031 ENSG00000164970 Family with sequence similarity 219, member A 9 34398184-34458570 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019338, HPA052909 Uncertain Supported Nucleoplasm
Golgi apparatus
Vesicles Expressed in all cerebral cortex: 76.3 -C9orf24 bA573M23.4, CBE1, MGC32921, MGC33614, NYD-SP22, SMRP1 ENSG00000164972 Chromosome 9 open reading frame 24 9 34379019-34397832 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053008 Uncertain Group enriched 11 fallopian tube: 172.5;testis: 65.1 lung: 11.0 -SNAPC3 MGC132011, MGC33124, PTFbeta, SNAP50 ENSG00000164975 Small nuclear RNA activating complex, polypeptide 3, 50kDa 9 15422704-15465953 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053145, HPA066031 Validated Nucleus
Nuclear bodies Mixed cerebral cortex: 11.9 -KIAA1161 NET37 ENSG00000164976 KIAA1161 9 34366670-34376853 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060533, HPA067487 Approved Approved Mitochondria Expressed in all skeletal muscle: 29.4 -NUDT2 APAH1 ENSG00000164978 Nudix (nucleoside diphosphate linked moiety X)-type motif 2 9 34329506-34343713 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004684, HPA044903, HPA058623, HPA067639 Uncertain Supported Nucleoplasm Expressed in all epididymis: 42.9 -TMEM65 ENSG00000164983 Transmembrane protein 65 8 124306189-124372692 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025020 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 17.4 -PSIP1 LEDGF, p52, p75, PSIP2 ENSG00000164985 PC4 and SFRS1 interacting protein 1 9 15464066-15511019 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013718, HPA019697 Supported Validated Nucleoplasm Expressed in all cerebral cortex: 161.8 -CCDC171 bA536D16.1, bA778P13.1, C9orf93, Em:AL513423.1, FLJ39267, FLJ46740 ENSG00000164989 Coiled-coil domain containing 171 9 15552897-16061663 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA019803, HPA019806, HPA024133 Uncertain Approved Nucleus Tissue enhanced 0 testis: 21.3 endometrium: 9.7 -UBAP1 UBAP ENSG00000165006 Ubiquitin associated protein 1 9 34179005-34252523 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019804, HPA041590 Approved Validated Plasma membrane
Cytosol Expressed in all testis: 88.4 -DIRAS2 Di-Ras2, DKFZp761C07121 ENSG00000165023 DIRAS family, GTP-binding RAS-like 2 9 90609832-90643104 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043758 Uncertain Tissue enriched 9 cerebral cortex: 124.9 cervix: 13.6 -SYK ENSG00000165025 Spleen tyrosine kinase 9 90801787-90898549 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001384, CAB007773 Supported Approved Vesicles
Plasma membrane
Cytosol Mixed parathyroid gland: 94.2 -NIPSNAP3B FLJ11275 ENSG00000165028 Nipsnap homolog 3B (C. elegans) 9 104764157-104777457 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042491 Uncertain Mixed adipose tissue: 15.5 -ABCA1 ABC1, HDLDT1, TGD ENSG00000165029 ATP-binding cassette, sub-family A (ABC1), member 1 9 104781002-104928237 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057283, CAB069889 Approved Approved Nucleoplasm
Vesicles Mixed adrenal gland: 38.1 -NFIL3 E4BP4, IL3BP1, NF-IL3A, NFIL3A ENSG00000165030 Nuclear factor, interleukin 3 regulated 9 91409045-91423862 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003261 Approved Approved Nuclear bodies Expressed in all bone marrow: 137.4 -LETM2 FLJ25409 ENSG00000165046 Leucine zipper-EF-hand containing transmembrane protein 2 8 38386207-38409527 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA025032, HPA053676 Uncertain Approved Nucleus
Nuclear bodies
Cytosol Tissue enriched 9 testis: 39.3 cerebral cortex: 4.2 -METTL2B FLJ11350, METL, METTL2 ENSG00000165055 Methyltransferase like 2B 7 128476729-128506602 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all skin: 12.9 -PRKACG PKACg ENSG00000165059 Protein kinase, cAMP-dependent, catalytic, gamma 9 69012505-69014113 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004530, HPA071185 Supported Approved Cytosol Tissue enriched 297 testis: 29.6 adipose tissue: 0.0 -FXN CyaY, FA, FARR, FRDA, X25 ENSG00000165060 Frataxin 9 69035259-69100178 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022164, HPA068304 Supported Supported Mitochondria
Cytosol Expressed in all parathyroid gland: 33.5 -ZMAT4 FLJ13842 ENSG00000165061 Zinc finger, matrin-type 4 8 40530590-40897833 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069813, HPA071585 Supported Supported Nucleus
Nucleoli Group enriched 8 cerebral cortex: 10.1;thyroid gland: 27.5 testis: 2.3 -NKX6-3 FLJ25169 ENSG00000165066 NK6 homeobox 3 8 41645178-41650669 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042790 Uncertain Tissue enhanced 0 duodenum: 17.7;stomach: 51.1 parathyroid gland: 7.8 -TMEM71 FLJ33069 ENSG00000165071 Transmembrane protein 71 8 132685007-132760712 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA058401, HPA070655 Uncertain Validated Mitochondria Mixed heart muscle: 24.2 -MAMDC2 MGC21981 ENSG00000165072 MAM domain containing 2 9 70043581-70226970 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021814, HPA022249 Uncertain Mixed endometrium: 60.2 -PRSS37 ENSG00000165076 Protease, serine, 37 7 141836286-141841487 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA020541 Uncertain Tissue enriched 155 testis: 55.0 epididymis: 0.3 -CPA6 CPAH ENSG00000165078 Carboxypeptidase A6 8 67422125-67746345 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 prostate: 6.9;rectum: 3.8 colon: 2.4 -C8orf34 vest-1, VEST1 ENSG00000165084 Chromosome 8 open reading frame 34 8 68330722-68819022 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044420, HPA053065 Uncertain Supported Nucleus
Nucleoli
Golgi apparatus Tissue enhanced 0 fallopian tube: 15.1;parathyroid gland: 19.7 cerebral cortex: 6.1 -TMC1 DFNA36, DFNB11, DFNB7 ENSG00000165091 Transmembrane channel-like 1 9 72521801-72836351 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cervix, uterine: 1.6 testis: 1.0 -ALDH1A1 ALDH1, PUMB1, RALDH1 ENSG00000165092 Aldehyde dehydrogenase 1 family, member A1 9 72900662-73080442 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002123, CAB020690 Approved Approved Validated Cytosol Expressed in all liver: 758.5 -KDM1B AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2 ENSG00000165097 Lysine (K)-specific demethylase 1B 6 18155329-18223853 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031269 Uncertain Approved Nucleus Expressed in all thyroid gland: 64.8 -HGSNAT FLJ32731, HGNAT, TMEM76 ENSG00000165102 Heparan-alpha-glucosaminide N-acetyltransferase 8 43140455-43202855 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029578 Approved Expressed in all parathyroid gland: 50.4 -RASEF FLJ31614, RAB45 ENSG00000165105 RAS and EF-hand domain containing 9 82979585-83063177 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021431 Approved Microtubules Expressed in all thyroid gland: 44.9 -GKAP1 FKSG21, GKAP42 ENSG00000165113 G kinase anchoring protein 1 9 83739421-83829516 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035117, HPA035118 Supported Approved Approved Microtubule organizing center
Cytosol Tissue enriched 21 testis: 362.7 skeletal muscle: 17.6 -KIF27 DKFZp434D0917 ENSG00000165115 Kinesin family member 27 9 83836698-83921465 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 48.5 thyroid gland: 14.3 -C9orf64 MGC10999 ENSG00000165118 Chromosome 9 open reading frame 64 9 83938311-83956986 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054903, HPA066190 Uncertain Approved Golgi apparatus Expressed in all thyroid gland: 27.3 -HNRNPK CSBP, HNRPK, TUNP ENSG00000165119 Heterogeneous nuclear ribonucleoprotein K 9 83968083-83980616 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004435, HPA007644, CAB016225, HPA044105 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 518.7 -SSMEM1 C7orf45, FLJ40316 ENSG00000165120 Serine-rich single-pass membrane protein 1 7 130207860-130216843 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 200 testis: 56.6 placenta: 0.2 -SVEP1 bA427L11.3, C9orf13, FLJ13529, POLYDOM ENSG00000165124 Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 9 110365251-110579880 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020610, HPA021520 Uncertain Tissue enhanced 0 placenta: 86.6 adipose tissue: 36.5 -TRPV6 CaT1, ECAC2 ENSG00000165125 Transient receptor potential cation channel, subfamily V, member 6 7 142871203-142885762 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA062864 Approved Tissue enhanced 0 prostate: 38.7;salivary gland: 29.3 placenta: 17.4 -C7orf34 CTM-1 ENSG00000165131 Chromosome 7 open reading frame 34 7 142939343-142940868 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 47 testis: 48.7 bone marrow: 1.0 -ANKS6 ANKRD14, FLJ36928, NPHP16, SAMD6 ENSG00000165138 Ankyrin repeat and sterile alpha motif domain containing 6 9 98731329-98796965 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008355 Approved Approved Nucleus
Nucleoli
Cytosol Mixed thyroid gland: 15.3 -FBP1 FBP ENSG00000165140 Fructose-1,6-bisphosphatase 1 9 94603133-94640249 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005857, HPA012513, CAB033869 Supported Uncertain Mitochondria Tissue enhanced 0 duodenum: 338.7;liver: 442.9 small intestine: 286.0 -TMEM246 C9orf125, MGC12992 ENSG00000165152 Transmembrane protein 246 9 101473171-101533537 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011318, HPA054041 Uncertain Approved Mitochondria Mixed cerebral cortex: 46.7 -ZHX1 ENSG00000165156 Zinc fingers and homeoboxes 1 8 123248451-123275541 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055357, HPA060251 Validated Nucleoplasm Expressed in all thyroid gland: 62.7 -CFAP47 CHDC2, CXorf22, CXorf30, CXorf59, FLJ36601, MGC34831, RP13-11B7.1 ENSG00000165164 Cilia and flagella associated protein 47 X 35919734-36385319 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA044633, HPA054859 Uncertain Tissue enriched 6 fallopian tube: 9.1 testis: 1.6 -CYBB CGD, GP91-PHOX, NOX2 ENSG00000165168 Cytochrome b-245, beta polypeptide X 37780011-37813461 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051227 Supported Tissue enhanced 0 appendix: 221.1 lung: 132.4 -DYNLT3 TCTE1L, TCTEX1L ENSG00000165169 Dynein, light chain, Tctex-type 3 X 37836757-37847637 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003938 Approved Expressed in all adrenal gland: 77.5 -WBSCR27 ENSG00000165171 Williams Beuren syndrome chromosome region 27 7 73834590-73842535 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA022420 Uncertain Supported Focal adhesion sites Mixed parathyroid gland: 8.3 -MID1IP1 FLJ10386, G12-like, MIG12, STRAIT11499, THRSPL ENSG00000165175 MID1 interacting protein 1 X 38801432-38806537 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038816 Uncertain Expressed in all bone marrow: 66.3 -C9orf84 FLJ32779 ENSG00000165181 Chromosome 9 open reading frame 84 9 111686173-111795008 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA032108 Approved Vesicles
Cytosol Tissue enriched 10 testis: 30.9 adrenal gland: 3.1 -CXorf58 FLJ25444 ENSG00000165182 Chromosome X open reading frame 58 X 23907801-23939507 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA031542, HPA031543, HPA031544 Uncertain Tissue enriched 10 testis: 6.2 fallopian tube: 0.6 -KIAA1958 FLJ39294 ENSG00000165185 KIAA1958 9 112486847-112669397 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020625 Approved Approved Plasma membrane
Cytosol Mixed ovary: 12.1 -PTCHD1 FLJ30296 ENSG00000165186 Patched domain containing 1 X 23334015-23404372 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046110 Uncertain Tissue enhanced 0 epididymis: 9.6 seminal vesicle: 5.3 -RNF183 MGC4734 ENSG00000165188 Ring finger protein 183 9 113297093-113303376 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057675 Uncertain Tissue enhanced 0 epididymis: 19.6;gallbladder: 9.0 kidney: 4.3 -ASB11 DKFZp779E2460 ENSG00000165192 Ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase X 15281697-15315656 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA000238 Uncertain Group enriched 6 heart muscle: 27.2;skeletal muscle: 42.1 stomach: 5.6 -PCDH19 EFMR, EIEE9, KIAA1313 ENSG00000165194 Protocadherin 19 X 100291644-100410273 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027533 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 10.8 cervix: 2.5 -PIGA GPI3 ENSG00000165195 Phosphatidylinositol glycan anchor biosynthesis, class A X 15319451-15335580 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001174 Approved Mixed lung: 10.5 -FIGF VEGF-D, VEGFD ENSG00000165197 C-fos induced growth factor (vascular endothelial growth factor D) X 15345591-15384376 Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027342 Uncertain Tissue enhanced 0 breast: 25.0;lung: 59.2 adipose tissue: 13.2 -OR1Q1 HSTPCR106, OR1Q2, OR1Q3, OR9-A, OST226, OST226OR9-A, TPCR106 ENSG00000165202 Olfactory receptor, family 1, subfamily Q, member 1 9 122614738-122615682 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA044828 Uncertain Not detected epididymis: 0.9 -OR1K1 hg99, MNAB ENSG00000165204 Olfactory receptor, family 1, subfamily K, member 1 9 122800123-122801073 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.2 -STRBP FLJ11307, ILF3L, SPNR ENSG00000165209 Spermatid perinuclear RNA binding protein 9 123109500-123268576 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020651 Approved Expressed in all testis: 78.6 -CLDN3 C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 ENSG00000165215 Claudin 3 7 73768997-73770270 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002702, HPA014361 Supported Supported Cell Junctions Tissue enhanced 0 colon: 89.6;small intestine: 121.9 duodenum: 56.5 -GAPVD1 DKFZP434C212, KIAA1521 ENSG00000165219 GTPase activating protein and VPS9 domains 1 9 125261794-125367207 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029386, HPA029387 Uncertain Supported Cytosol Expressed in all testis: 49.0 -CARD19 bA370F5.1, BinCARD, C9orf89, MGC11115 ENSG00000165233 Caspase recruitment domain family, member 19 9 93096218-93113283 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010921, HPA010990, HPA038297 Approved Supported Mitochondria Mixed testis: 11.2 -WNK2 KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43 ENSG00000165238 WNK lysine deficient protein kinase 2 9 93184916-93320572 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015555, HPA016519, CAB017813 Supported Approved Cytosol Mixed heart muscle: 33.2 -ATP7A MNK ENSG00000165240 ATPase, Cu++ transporting, alpha polypeptide X 77910656-78050395 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012887, HPA048107 Approved Supported Golgi apparatus
Vesicles Mixed parathyroid gland: 15.0 -ZNF367 FLJ33970 ENSG00000165244 Zinc finger protein 367 9 96385941-96418329 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA015319, HPA015785 Uncertain Supported Nucleoplasm Tissue enhanced 0 bone marrow: 16.0 testis: 11.2 -NLGN4Y KIAA0951 ENSG00000165246 Neuroligin 4, Y-linked Y 14522638-14845650 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA001651 Approved Tissue enhanced 0 prostate: 11.0;seminal vesicle: 12.3 cerebral cortex: 7.4 -HDX CXorf43, FLJ30678 ENSG00000165259 Highly divergent homeobox X 84317874-84502479 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047189 Approved Approved Cytosol Mixed cerebral cortex: 3.8 -NDUFB6 B17, CI ENSG00000165264 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 9 32552999-32573184 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044001, HPA053334 Supported Validated Mitochondria Expressed in all cerebral cortex: 70.5 -AQP7 AQP7L, AQP9, AQPap ENSG00000165269 Aquaporin 7 9 33383179-33402682 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adipose tissue: 315.4 parathyroid gland: 65.5 -NOL6 bA311H10.1, FLJ21959, MGC14896, MGC14921, MGC20838, Nrap, UTP22 ENSG00000165271 Nucleolar protein 6 (RNA-associated) 9 33461441-33473930 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055891, HPA061002 Supported Validated Nucleus
Nucleoli
Mitochondria Expressed in all parathyroid gland: 28.1 -AQP3 GIL ENSG00000165272 Aquaporin 3 (Gill blood group) 9 33441154-33447611 Blood group antigen proteins, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014924 Supported Supported Nucleus
Plasma membrane Expressed in all esophagus: 975.2 -TRMT10B bA3J10.9, FLJ31455, RG9MTD3 ENSG00000165275 TRNA methyltransferase 10B 9 37753803-37778972 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA021800 Uncertain Approved Nucleoplasm
Plasma membrane Mixed skin: 13.0 -VCP IBMPFD, p97 ENSG00000165280 Valosin containing protein 9 35056064-35073249 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005593, HPA012728, HPA012814 Supported Validated Nucleoplasm
Cytosol Expressed in all parathyroid gland: 92.6 -PIGO DKFZp434M222, FLJ00135 ENSG00000165282 Phosphatidylinositol glycan anchor biosynthesis, class O 9 35088688-35096601 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014905 Approved Nucleus
Nucleoli Expressed in all parathyroid gland: 73.2 -STOML2 HSPC108, SLP-2 ENSG00000165283 Stomatin (EPB72)-like 2 9 35099776-35103195 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015944, HPA062016 Approved Supported Plasma membrane
Cytosol Expressed in all fallopian tube: 97.5 -BRWD3 FLJ38568, MRX93 ENSG00000165288 Bromodomain and WD repeat domain containing 3 X 80670854-80809688 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012802 Approved Approved Nucleoplasm
Cytosol Mixed testis: 8.6 -SLITRK5 bA364G4.2, KIAA0918, LRRC11 ENSG00000165300 SLIT and NTRK-like family, member 5 13 87672615-87696272 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA013843 Uncertain Supported Nucleoplasm
Golgi apparatus Tissue enhanced 0 cerebral cortex: 4.9;fallopian tube: 4.7 seminal vesicle: 1.8 -MELK KIAA0175 ENSG00000165304 Maternal embryonic leucine zipper kinase 9 36572862-36677683 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017214 Uncertain Tissue enhanced 0 testis: 16.8 lymph node: 11.9 -ARMC3 CT81, FLJ32827 ENSG00000165309 Armadillo repeat containing 3 10 22928024-23038523 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037823, HPA037824 Supported Group enriched 12 fallopian tube: 73.4;testis: 60.7 lung: 5.5 -OTUD1 DUBA7, OTDC1 ENSG00000165312 OTU deubiquitinase 1 10 23439458-23442390 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038503, HPA038504 Uncertain Approved Nucleoplasm
Nuclear bodies
Golgi apparatus Expressed in all bone marrow: 43.4 -ARHGAP12 FLJ10971, FLJ20737, FLJ21785 ENSG00000165322 Rho GTPase activating protein 12 10 31805404-31928876 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000412 Approved Expressed in all parathyroid gland: 44.4 -FAT3 CDHF15, CDHR10, KIAA1989 ENSG00000165323 FAT atypical cadherin 3 11 92352096-92896470 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026878 Uncertain Tissue enhanced 0 cerebral cortex: 3.9;seminal vesicle: 2.6 prostate: 1.6 -CCDC67 FLJ25393 ENSG00000165325 Coiled-coil domain containing 67 11 93329971-93438487 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA010986 Uncertain Group enriched 11 fallopian tube: 7.6;testis: 29.8 prostate: 1.6 -HECTD2 FLJ37306 ENSG00000165338 HECT domain containing E3 ubiquitin protein ligase 2 10 91409280-91514829 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA037767 Approved Approved Nucleoplasm Mixed prostate: 26.7 -SLC7A3 ATRC3, CAT-3, FLJ14541 ENSG00000165349 Solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 X 70925582-70931125 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003629 Approved Tissue enhanced 0 endometrium: 7.8;prostate: 9.6;seminal vesicle: 7.4 smooth muscle: 4.0 -FBXO33 Fbx33 ENSG00000165355 F-box protein 33 14 39397669-39432500 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046657 Approved Approved Nucleoplasm Expressed in all bone marrow: 33.4 -DDX26B FLJ41215 ENSG00000165359 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B X 135520659-135582510 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013200, HPA013335, HPA030747 Approved Approved Centrosome
Mitochondria Mixed lymph node: 13.5 -GPR101 ENSG00000165370 G protein-coupled receptor 101 X 137030148-137031674 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level HPA001084 Uncertain Not detected cerebral cortex: 0.1 -CLDN2 ENSG00000165376 Claudin 2 X 106900164-106930861 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002609, HPA051548 Supported Supported Nucleoplasm
Cell Junctions Tissue enhanced 0 gallbladder: 159.7;kidney: 170.5;seminal vesicle: 128.0 epididymis: 40.4 -LRFN5 C14orf146, FIGLER8, SALM5 ENSG00000165379 Leucine rich repeat and fibronectin type III domain containing 5 14 41607570-41904549 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001177 Uncertain Tissue enhanced 0 parathyroid gland: 51.4 cervix: 16.7 -LRRC18 MGC34773, UNQ933, UNQ9338, VKGE9338 ENSG00000165383 Leucine rich repeat containing 18 10 48909483-48935190 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039256 Uncertain Group enriched 8 fallopian tube: 11.9;testis: 25.1 lung: 2.3 -SPTSSA C14orf147, ssSPTa ENSG00000165389 Serine palmitoyltransferase, small subunit A 14 34432789-34462356 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all adrenal gland: 90.6 -WRN RECQ3, RECQL2 ENSG00000165392 Werner syndrome, RecQ helicase-like 8 31033801-31173769 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028661 Approved Supported Nuclear speckles Mixed endometrium: 14.7 -MARCH8 c-MIR, CMIR, MARCH-VIII, MIR, RNF178 ENSG00000165406 Membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 10 45454585-45594906 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA014597 Approved Expressed in all testis: 104.3 -TSHR LGR3 ENSG00000165409 Thyroid stimulating hormone receptor 14 80954989-81146302 Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB000473 Approved Tissue enriched 277 thyroid gland: 443.8 lymph node: 1.6 -CFL2 NEM7 ENSG00000165410 Cofilin 2 (muscle) 14 34706769-34714823 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037078, HPA045599 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all skeletal muscle: 242.8 -SUGT1 SGT1 ENSG00000165416 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 13 52652709-52700909 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015942, HPA043949 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 63.2 -GTF2A1 TFIIA ENSG00000165417 General transcription factor IIA, 1, 19/37kDa 14 81175452-81221377 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000869 Uncertain Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 38.8 -ZCCHC24 C10orf56, FLJ90798, Z3CXXC8 ENSG00000165424 Zinc finger, CCHC domain containing 24 10 79382325-79445627 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038348 Approved Approved Nucleoplasm
Mitochondria Expressed in all cerebral cortex: 70.8 -PGM2L1 BM32A, FLJ32029 ENSG00000165434 Phosphoglucomutase 2-like 1 11 74330318-74398473 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056995, HPA060948 Supported Approved Mitochondria Tissue enriched 9 cerebral cortex: 64.3 endometrium: 7.3 -PHYHIPL Em:AC025038.1, KIAA1796 ENSG00000165443 Phytanoyl-CoA 2-hydroxylase interacting protein-like 10 59176590-59247774 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038746 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 89.6 adrenal gland: 22.5 -SLC16A9 C10orf36, FLJ43803, MCT9 ENSG00000165449 Solute carrier family 16, member 9 10 59650761-59736002 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA049286 Approved Approved Nucleus
Cell Junctions Tissue enhanced 0 adrenal gland: 199.5;kidney: 199.2 spleen: 57.0 -FOLR2 ENSG00000165457 Folate receptor 2 (fetal) 11 72216601-72221950 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all placenta: 233.7 -INPPL1 SHIP2 ENSG00000165458 Inositol polyphosphate phosphatase-like 1 11 72223701-72239105 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037601 Approved Supported Golgi apparatus
Cytosol Expressed in all spleen: 65.5 -PHOX2A ARIX, CFEOM2, FEOM2, PMX2A ENSG00000165462 Paired-like homeobox 2a 11 72239077-72245664 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065621 Approved Nucleus
Nuclear membrane
Vesicles Tissue enriched 14 adrenal gland: 26.5 appendix: 1.8 -MBL2 COLEC1, MBL ENSG00000165471 Mannose-binding lectin (protein C) 2, soluble 10 52765380-52771700 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002027, CAB016782 Supported Tissue enriched 1413 liver: 141.3 adipose tissue: 0.0 -GJB2 CX26, DFNA3, DFNB1, NSRD1 ENSG00000165474 Gap junction protein, beta 2, 26kDa 13 20187470-20192898 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013093, HPA014362 Uncertain Approved Mitochondria Tissue enriched 9 esophagus: 728.4 tonsil: 84.8 -CRYL1 GDH, lambda-CRY, MGC149525, MGC149526 ENSG00000165475 Crystallin, lambda 1 13 20403667-20525857 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040403 Supported Approved Nucleus
Nucleoli
Golgi apparatus
Plasma membrane Expressed in all kidney: 335.8 -REEP3 C10orf74 ENSG00000165476 Receptor accessory protein 3 10 63521363-63625123 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 55.8 -HEPACAM FLJ25530, GLIALCAM, hepaCAM ENSG00000165478 Hepatic and glial cell adhesion molecule 11 124919193-124936412 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017613, CAB025486 Supported Approved Vesicles Tissue enriched 6 cerebral cortex: 80.9 adipose tissue: 14.4 -SKA3 C13orf3, MGC4832, RAMA1 ENSG00000165480 Spindle and kinetochore associated complex subunit 3 13 21153595-21176602 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039272 Approved Uncertain Plasma membrane
Cytosol Tissue enhanced 0 testis: 10.2 lymph node: 5.1 -MICU2 EFHA1 ENSG00000165487 Mitochondrial calcium uptake 2 13 21492691-21604214 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045511, HPA058790 Approved Approved Nucleus
Mitochondria Expressed in all kidney: 77.9 -DDIAS C11orf82, FLJ25416, FLJ38838, noxin ENSG00000165490 DNA damage-induced apoptosis suppressor 11 82899975-82958277 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA038540, HPA038541 Approved Approved Plasma membrane
Cytosol Tissue enhanced 0 testis: 20.1 skeletal muscle: 6.4 -PCF11 KIAA0824 ENSG00000165494 PCF11 cleavage and polyadenylation factor subunit 11 83156988-83187451 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040779 Supported Nucleoplasm
Mitochondria Expressed in all testis: 44.2 -PKNOX2 ENSG00000165495 PBX/knotted 1 homeobox 2 11 125164687-125433389 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA028867, CAB034342, HPA055368, HPA066962 Supported Validated Nucleoplasm Mixed thyroid gland: 20.1 -RPL10L ENSG00000165496 Ribosomal protein L10-like 14 46651010-46651821 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011311 Uncertain Approved Endoplasmic reticulum
Cytosol Tissue enriched 44 testis: 126.2 rectum: 2.8 -LRR1 LRR-1, MGC20689, PPIL5 ENSG00000165501 Leucine rich repeat protein 1 14 49598697-49614672 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065703, HPA069364 Approved Approved Nucleoplasm
Nuclear membrane
Vesicles Tissue enhanced 0 testis: 33.3 lymph node: 12.3 -RPL36AL RPL36A ENSG00000165502 Ribosomal protein L36a-like 14 49618519-49620685 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077586 Approved Plasma membrane
Cytosol Expressed in all ovary: 528.8 -DNAAF2 C14orf104, CILD10, FLJ10563, KTU, PF13 ENSG00000165506 Dynein, axonemal, assembly factor 2 14 49625174-49635230 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002894, HPA004113 Approved Supported Cytosol Expressed in all fallopian tube: 13.8 -C10orf10 DEPP, FIG, Fseg ENSG00000165507 Chromosome 10 open reading frame 10 10 44970981-44978810 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB013687, HPA037819 Uncertain Approved Nucleus
Vesicles Expressed in all adipose tissue: 236.8 -MAGEC3 CT7.2, HCA2, MAGE-C3 ENSG00000165509 Melanoma antigen family C3 X 141838316-141897832 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052067 Approved Tissue enhanced 0 testis: 1.0 cerebral cortex: 0.6 -ZNF22 HKR-T1, KOX15, Zfp422, ZNF422 ENSG00000165512 Zinc finger protein 22 10 45000475-45005326 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016736, HPA054893 Approved Validated Nucleus Expressed in all placenta: 46.6 -KLHDC2 HCLP-1, LCP ENSG00000165516 Kelch domain containing 2 14 49767608-49786385 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000628 Approved Supported Nucleoplasm
Nuclear membrane
Nuclear bodies Expressed in all thyroid gland: 47.0 -EML5 EMAP-2, HuEMAP-2 ENSG00000165521 Echinoderm microtubule associated protein like 5 14 88612431-88792752 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054019, HPA055379 Uncertain Tissue enhanced 0 ovary: 24.4 prostate: 10.6 -NEMF FLJ10051, NY-CO-1, SDCCAG1 ENSG00000165525 Nuclear export mediator factor 14 49782083-49853203 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004160 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all parathyroid gland: 45.1 -RPUSD4 FLJ14494 ENSG00000165526 RNA pseudouridylate synthase domain containing 4 11 126202094-126211692 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039689 Approved Approved Nucleoplasm
Mitochondria Expressed in all skeletal muscle: 44.9 -ARF6 ENSG00000165527 ADP-ribosylation factor 6 14 49893092-49897054 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002778 Approved Expressed in all esophagus: 96.9 -TTC8 BBS8, RP51 ENSG00000165533 Tetratricopeptide repeat domain 8 14 88824153-88881078 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003310 Uncertain Expressed in all ovary: 90.7 -TMEM63C C14orf171, CSC1, DKFZp434P0111, hsCSC1 ENSG00000165548 Transmembrane protein 63C 14 77116568-77259495 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030657 Uncertain Approved Centrosome Tissue enhanced 0 adrenal gland: 12.9;cerebral cortex: 18.6;testis: 13.8 epididymis: 5.5 -NGB ENSG00000165553 Neuroglobin 14 77265483-77271312 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042615, HPA058596 Supported Group enriched 5 adrenal gland: 10.2;cerebral cortex: 4.8;fallopian tube: 2.1 pancreas: 1.0 -NOXRED1 C14orf148, FLJ32809 ENSG00000165555 NADP-dependent oxidoreductase domain containing 1 14 77394021-77423517 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055658 Approved Tissue enhanced 0 testis: 12.1 parathyroid gland: 2.5 -CDX2 CDX3 ENSG00000165556 Caudal type homeobox 2 13 27962137-27971139 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB002221, HPA045669, HPA049580 Supported Supported Nucleoplasm Group enriched 6 colon: 31.4;duodenum: 22.9;rectum: 25.3;small intestine: 30.8 appendix: 4.9 -AMER2 FAM123A, FLJ25477 ENSG00000165566 APC membrane recruitment protein 2 13 25161684-25172288 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039458 Supported Tissue enriched 53 cerebral cortex: 72.6 testis: 1.3 -AKR1E2 AKR1CL2, AKRDC1, MGC10612 ENSG00000165568 Aldo-keto reductase family 1, member E2 10 4786629-4848062 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037821, HPA037822 Uncertain Validated Nucleoplasm
Golgi apparatus Tissue enhanced 0 testis: 30.0 thyroid gland: 6.1 -KBTBD6 DKFZp547E1912 ENSG00000165572 Kelch repeat and BTB (POZ) domain containing 6 13 41127569-41132746 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046861, HPA048914 Uncertain Mixed cerebral cortex: 23.7 -SSX5 ENSG00000165583 Synovial sarcoma, X breakpoint 5 X 48186220-48277578 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045683 Uncertain Tissue enhanced 0 thyroid gland: 1.0 testis: 0.9 -SSX3 CT5.3 ENSG00000165584 Synovial sarcoma, X breakpoint 3 X 48346428-48356707 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045683 Approved Tissue enriched 70 testis: 25.2 thyroid gland: 0.3 -OTX2 ENSG00000165588 Orthodenticle homeobox 2 14 56799905-56810479 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000633 Approved Not detected testis: 0.5 -FAAH2 AMDD, FAAH-2, FLJ31204, RP11-479E16.1 ENSG00000165591 Fatty acid amide hydrolase 2 X 57286706-57489196 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed parathyroid gland: 19.8 -DRGX DRG11, PRRXL1 ENSG00000165606 Dorsal root ganglia homeobox 10 49364181-49396016 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA043978 Uncertain Approved Nucleus
Nucleoli
Cytosol Tissue enriched 11 adrenal gland: 8.9 skin: 0.8 -NUDT5 hYSAH1, YSA1H ENSG00000165609 Nudix (nucleoside diphosphate linked moiety X)-type motif 5 10 12165325-12196144 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019827 Approved Approved Nucleus
Vesicles
Centrosome Expressed in all thyroid gland: 45.5 -DACT1 DAPPER, DAPPER1, FRODO, HDPR1, THYEX3 ENSG00000165617 Dishevelled-binding antagonist of beta-catenin 1 14 58633967-58648321 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003016 Uncertain Supported Nucleoplasm Mixed gallbladder: 40.4 -OXGR1 aKGR, GPR80, GPR99, P2RY15, P2Y15 ENSG00000165621 Oxoglutarate (alpha-ketoglutarate) receptor 1 13 96985719-96994730 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA067673 Supported Plasma membrane Mixed breast: 5.2 -UCMA C10orf49 ENSG00000165623 Upper zone of growth plate and cartilage matrix associated 10 13221767-13234334 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046718 Uncertain Tissue enhanced 0 ovary: 1.4 heart muscle: 0.3 -BEND7 C10orf30, FLJ40283 ENSG00000165626 BEN domain containing 7 10 13438484-13528974 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037835 Uncertain Approved Nucleus
Nucleoli fibrillar center
Vesicles Mixed thyroid gland: 40.7 -ATP5C1 ATP5C, ATP5CL1 ENSG00000165629 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 10 7788129-7807815 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060949 Approved Expressed in all heart muscle: 446.4 -PRPF18 hPrp18 ENSG00000165630 Pre-mRNA processing factor 18 10 13586927-13630868 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037599, HPA047950 Supported Approved Nuclear speckles
Cytosol Expressed in all thyroid gland: 38.3 -TAF3 TAF140, TAFII140 ENSG00000165632 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 10 7818504-8016627 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066184 Supported Nucleoplasm
Nuclear membrane Mixed testis: 14.1 -VSTM4 C10orf72, FLJ31737 ENSG00000165633 V-set and transmembrane domain containing 4 10 49014245-49115509 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA017279 Uncertain Approved Nucleus
Vesicles Mixed adrenal gland: 55.1 -VDAC2 ENSG00000165637 Voltage-dependent anion channel 2 10 75210154-75231448 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043475 Supported Validated Mitochondria Expressed in all esophagus: 266.4 -SOHLH1 bA100C15.3, bHLHe80, C9orf157, NOHLH, SPATA27, TEB2 ENSG00000165643 Spermatogenesis and oogenesis specific basic helix-loop-helix 1 9 135693407-135699528 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA059439 Approved Nuclear speckles Group enriched 27 cerebral cortex: 6.4;testis: 13.4 skin: 0.3 -COMTD1 FLJ23841 ENSG00000165644 Catechol-O-methyltransferase domain containing 1 10 75233969-75236030 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042165 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Mixed duodenum: 14.0 -SLC18A2 SVAT, SVMT, VMAT2 ENSG00000165646 Solute carrier family 18 (vesicular monoamine transporter), member 2 10 117241093-117279430 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cervix, uterine: 43.2 adrenal gland: 19.1 -PDZD8 bA129M16.2, FLJ34427, PDZK8 ENSG00000165650 PDZ domain containing 8 10 117277274-117375467 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015716, HPA051610 Uncertain Approved Nucleoli fibrillar center
Plasma membrane Expressed in all bone marrow: 46.6 -ZNF503 FLJ45745, MGC2555, Nlz2 ENSG00000165655 Zinc finger protein 503 10 75397830-75401906 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026848 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Mixed adrenal gland: 25.9 -FAM175B ABRO1, Em:AC068896.4, KIAA0157 ENSG00000165660 Family with sequence similarity 175, member B 10 124801785-124836670 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037591, HPA037592, HPA074089 Approved Approved Cytosol Expressed in all thyroid gland: 20.9 -QSOX2 DKFZp762A2013, QSCN6L1, SOXN ENSG00000165661 Quiescin Q6 sulfhydryl oxidase 2 9 136206333-136245841 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012716, HPA017280 Uncertain Validated Nucleoplasm
Golgi apparatus Expressed in all lymph node: 20.9 -FAM204A bA319I23.1, C10orf84, FLJ13188 ENSG00000165669 Family with sequence similarity 204, member A 10 118297930-118342328 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038182, HPA062025 Approved Supported Nucleus
Nucleoli Expressed in all testis: 89.0 -NSD1 ARA267, FLJ22263, KMT3B, STO ENSG00000165671 Nuclear receptor binding SET domain protein 1 5 177133025-177300215 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048431, HPA070333 Supported Nucleus
Plasma membrane Expressed in all testis: 43.2 -PRDX3 AOP-1, AOP1, MER5, SP-22 ENSG00000165672 Peroxiredoxin 3 10 119167703-119178833 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008656, HPA041488 Supported Expressed in all adrenal gland: 431.2 -ENOX2 APK1, COVA1, tNOX ENSG00000165675 Ecto-NOX disulfide-thiol exchanger 2 X 130623369-130903317 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000514 Uncertain Approved Nucleus
Actin filaments Expressed in all endometrium: 19.9 -GHITM DERP2, HSPC282, My021, PTD010, TMBIM5 ENSG00000165678 Growth hormone inducible transmembrane protein 10 84139440-84153555 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016464, HPA061664 Approved Supported Mitochondria Expressed in all kidney: 349.8 -CLEC1B CLEC2 ENSG00000165682 C-type lectin domain family 1, member B 12 9985642-10013424 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 liver: 33.7 bone marrow: 5.6 -SNAPC4 FLJ13451, PTFalpha, SNAP190 ENSG00000165684 Small nuclear RNA activating complex, polypeptide 4, 190kDa 9 136375577-136398797 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046627, HPA073243 Uncertain Approved Nucleoplasm
Nuclear membrane Expressed in all testis: 14.1 -TMEM52B C12orf59, FLJ31166 ENSG00000165685 Transmembrane protein 52B 12 10170542-10191801 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA058096 Supported Approved Focal adhesion sites Tissue enriched 21 kidney: 182.6 placenta: 8.7 -PMPCA Alpha-MPP, INPP5E, KIAA0123 ENSG00000165688 Peptidase (mitochondrial processing) alpha 9 136410570-136423761 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021648, HPA063735 Supported Validated Mitochondria Expressed in all adrenal gland: 38.8 -SDCCAG3 NY-CO-3 ENSG00000165689 Serologically defined colon cancer antigen 3 9 136401922-136410609 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029303 Approved Expressed in all testis: 36.3 -FRMD7 FLJ43346, NYS, NYS1 ENSG00000165694 FERM domain containing 7 X 132076993-132128020 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA000886 Uncertain Tissue enhanced 0 endometrium: 2.8;kidney: 3.0;smooth muscle: 3.4 seminal vesicle: 0.7 -AK8 C9orf98, FLJ32704 ENSG00000165695 Adenylate kinase 8 9 132725578-132878777 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA021443, HPA021445, HPA023894 Approved Tissue enhanced 0 fallopian tube: 29.6;testis: 21.6 epididymis: 12.3 -C9orf9 Mast ENSG00000165698 Chromosome 9 open reading frame 9 9 132878027-132890201 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022243, HPA051600 Supported Approved Mitochondria Group enriched 5 epididymis: 88.9;fallopian tube: 62.4;testis: 129.6 thyroid gland: 17.9 -TSC1 hamartin, KIAA0243, LAM, TSC ENSG00000165699 Tuberous sclerosis 1 9 132891348-132944633 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011568, CAB012481, HPA074132 Supported Validated Cytosol Expressed in all testis: 34.3 -GFI1B ZNF163B ENSG00000165702 Growth factor independent 1B transcription repressor 9 132945533-132991687 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level CAB004420 Supported Tissue enriched 15 bone marrow: 23.7 testis: 1.5 -HPRT1 HGPRT, HPRT ENSG00000165704 Hypoxanthine phosphoribosyltransferase 1 X 134460153-134520513 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006360, CAB012200 Supported Supported Cytosol Expressed in all testis: 138.3 -BORCS5 LOH12CR1, LOH1CR12 ENSG00000165714 BLOC-1 related complex subunit 5 12 12357079-12469694 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039509, HPA043627 Approved Supported Cytosol Mixed cerebral cortex: 7.4 -FAM69B C9orf136, MGC20262 ENSG00000165716 Family with sequence similarity 69, member B 9 136712570-136724050 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046812, HPA054443 Uncertain Approved Nucleus
Nuclear bodies
Vesicles Expressed in all placenta: 29.6 -ZMYND19 MIZIP ENSG00000165724 Zinc finger, MYND-type containing 19 9 137582079-137590490 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020642, HPA050761 Supported Approved Golgi apparatus
Vesicles Expressed in all testis: 46.2 -STOX1 C10orf24, FLJ25162 ENSG00000165730 Storkhead box 1 10 68827541-68895432 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037844, HPA037845 Approved Supported Nucleoplasm
Nucleoli fibrillar center
Cytosol Tissue enhanced 0 fallopian tube: 19.8 cerebral cortex: 14.1 -RET CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 ENSG00000165731 Ret proto-oncogene 10 43077027-43130351 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002581, HPA008356, HPA008495, CAB018342 Approved Supported Supported Vesicles
Plasma membrane
Cytosol Tissue enriched 5 parathyroid gland: 146.8 adrenal gland: 29.2 -DDX21 GURDB, RH-II/GU ENSG00000165732 DEAD (Asp-Glu-Ala-Asp) box helicase 21 10 68956128-68985073 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036592, HPA036593 Supported Validated Nucleus
Nucleoli Expressed in all appendix: 73.1 -BMS1 BMS1L, KIAA0187 ENSG00000165733 BMS1 ribosome biogenesis factor 10 42782801-42834937 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036589, HPA043081 Uncertain Validated Nucleus
Nucleoli Expressed in all parathyroid gland: 20.0 -STK32C MGC23665, PKE, YANK3 ENSG00000165752 Serine/threonine kinase 32C 10 132207492-132331847 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017894 Uncertain Expressed in all testis: 52.8 -KIAA1462 JCAD ENSG00000165757 KIAA1462 10 30012800-30115494 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017956 Approved Supported Vesicles
Cell Junctions Mixed placenta: 48.3 -OR4K2 ENSG00000165762 Olfactory receptor, family 4, subfamily K, member 2 14 19876232-19877309 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -FUNDC2 DC44, HCBP6 ENSG00000165775 FUN14 domain containing 2 X 155025980-155060303 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059129 Approved Expressed in all ovary: 7.8 -TMEM55B C14orf9, MGC26684 ENSG00000165782 Transmembrane protein 55B 14 20457719-20461612 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048528 Approved Expressed in all parathyroid gland: 41.2 -METTL17 FLJ20859, METT11D1 ENSG00000165792 Methyltransferase like 17 14 20989770-20997035 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002955, HPA059802 Uncertain Validated Nucleus Expressed in all adrenal gland: 23.9 -SLC39A2 ZIP2 ENSG00000165794 Solute carrier family 39 (zinc transporter), member 2 14 20999255-21001871 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA030489 Uncertain Group enriched 12 esophagus: 19.0;prostate: 20.5;seminal vesicle: 46.3;skin: 34.2 tonsil: 2.6 -NDRG2 KIAA1248, SYLD ENSG00000165795 NDRG family member 2 14 21016763-21070872 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002896, HPA003590, CAB017491 Supported Approved Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all cerebral cortex: 1032.4 -RNASE7 RAE1 ENSG00000165799 Ribonuclease, RNase A family, 7 14 21042226-21044234 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005690, CAB062560, CAB068225 Supported Tissue enhanced 0 esophagus: 72.3;skin: 29.3;tonsil: 20.4 gallbladder: 11.1 -ARHGEF40 FLJ10357, solo ENSG00000165801 Rho guanine nucleotide exchange factor (GEF) 40 14 21070270-21090240 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030746, HPA030757 Uncertain Expressed in all adrenal gland: 32.7 -NSMF NELF ENSG00000165802 NMDA receptor synaptonuclear signaling and neuronal migration factor 9 137447570-137459334 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044316 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 195.4 -ZNF219 ENSG00000165804 Zinc finger protein 219 14 21090046-21104722 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030761, HPA056168 Approved Supported Nucleus Expressed in all skin: 44.0 -C12orf50 FLJ35821 ENSG00000165805 Chromosome 12 open reading frame 50 12 87980035-88034037 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 871 testis: 87.0 epididymis: 0.0 -CASP7 CMH-1, ICE-LAP3, MCH3 ENSG00000165806 Caspase 7, apoptosis-related cysteine peptidase 10 113679162-113730907 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025563 Approved Expressed in all small intestine: 75.9 -PPP1R36 C14orf50 ENSG00000165807 Protein phosphatase 1, regulatory subunit 36 14 64549902-64589380 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 fallopian tube: 17.2;testis: 58.5 duodenum: 6.8 -BTNL9 BTN8, FLJ32535 ENSG00000165810 Butyrophilin-like 9 5 181040225-181061523 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043429 Approved Nuclear membrane
Vesicles Tissue enhanced 0 adipose tissue: 166.7 lung: 56.0 -CCDC186 C10orf118, FLJ10188, FLJ35301 ENSG00000165813 Coiled-coil domain containing 186 10 114120862-114174220 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014569, HPA018019 Approved Approved Golgi apparatus Expressed in all testis: 32.2 -VWA2 AMACO, CCSP-2, FLJ16213, FLJ45857, NET42 ENSG00000165816 Von Willebrand factor A domain containing 2 10 114239330-114291513 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037847 Uncertain Tissue enhanced 0 fallopian tube: 11.0 stomach: 7.8 -METTL3 M6A, MT-A70, Spo8 ENSG00000165819 Methyltransferase like 3 14 21498133-21511375 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 33.6 -SALL2 Hsal2, KIAA0360, ZNF795 ENSG00000165821 Spalt-like transcription factor 2 14 21521081-21537216 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004162 Approved Approved Nucleus
Vesicles Tissue enhanced 0 parathyroid gland: 66.6 cerebral cortex: 42.5 -PRAP1 UPA ENSG00000165828 Proline-rich acidic protein 1 10 133309410-133352683 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035360, HPA038713, HPA052451 Supported Approved Nucleoplasm
Vesicles
Plasma membrane Group enriched 6 duodenum: 981.7;liver: 306.9;small intestine: 1145.9 kidney: 136.1 -TRUB1 PUS4 ENSG00000165832 TruB pseudouridine (psi) synthase family member 1 10 114938193-114977676 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037914, HPA057552 Approved Supported Vesicles
Actin filaments Expressed in all adrenal gland: 38.7 -ERICH6B FAM194B, FLJ32682 ENSG00000165837 Glutamate-rich 6B 13 45534522-45615739 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB034242, HPA040358, HPA043559 Uncertain Tissue enriched 35 testis: 3.4 adipose tissue: 0.0 -CYP2C19 CPCJ, CYP2C, P450IIC19 ENSG00000165841 Cytochrome P450, family 2, subfamily C, polypeptide 19 10 94762624-94853260 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015066 Supported Tissue enhanced 0 duodenum: 49.7;liver: 125.5 small intestine: 21.2 -ZFYVE1 DFCP1, KIAA1589, PPP1R172, TAFF1, ZNFN2A1 ENSG00000165861 Zinc finger, FYVE domain containing 1 14 72969451-73027212 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002898 Approved Expressed in all testis: 22.6 -C10orf82 Em:AC016825.4, MGC33547 ENSG00000165863 Chromosome 10 open reading frame 82 10 116663696-116670264 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043022 Approved Mitochondria Tissue enriched 25 testis: 111.2 ovary: 4.4 -HSPA12A FLJ13874, KIAA0417 ENSG00000165868 Heat shock 70kDa protein 12A 10 116671192-116742574 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011273, HPA073244 Approved Approved Golgi apparatus
Cytosol Tissue enhanced 0 cerebral cortex: 65.2 adrenal gland: 26.9 -FRAT1 ENSG00000165879 Frequently rearranged in advanced T-cell lymphomas 1 10 97319267-97321915 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB046472, HPA055258 Approved Approved Vesicles
Cytosol Mixed spleen: 9.4 -UBTD1 FLJ11807 ENSG00000165886 Ubiquitin domain containing 1 10 97498868-97571209 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034825 Uncertain Approved Vesicles
Plasma membrane
Cytosol Mixed testis: 34.1 -ANKRD2 ARPP ENSG00000165887 Ankyrin repeat domain 2 (stretch responsive muscle) 10 97572499-97583884 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040842, HPA040884 Supported Validated Vesicles Group enriched 13 heart muscle: 29.9;skeletal muscle: 119.4 kidney: 5.6 -E2F7 ENSG00000165891 E2F transcription factor 7 12 77021247-77065580 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064866 Supported Nuclear speckles Tissue enhanced 0 testis: 5.1 bone marrow: 3.1 -ARHGAP42 FLJ32810, GRAF3 ENSG00000165895 Rho GTPase activating protein 42 11 100687653-100991937 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039924 Approved Approved Nuclear speckles Mixed placenta: 23.4 -ISCA2 HBLD1, ISA2 ENSG00000165898 Iron-sulfur cluster assembly 2 14 74493720-74497106 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030492 Approved Expressed in all epididymis: 55.6 -OTOGL C12orf64, FLJ90579 ENSG00000165899 Otogelin-like 12 80209453-80379090 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040364, HPA053392 Uncertain Approved Cytosol Tissue enhanced 0 kidney: 6.1 heart muscle: 1.3 -GYLTL1B FLJ35207, LARGE2, PP5656 ENSG00000165905 Glycosyltransferase-like 1B 11 45921621-45929096 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056621 Approved Tissue enhanced 0 placenta: 52.5 parathyroid gland: 21.3 -PACSIN3 SDPIII ENSG00000165912 Protein kinase C and casein kinase substrate in neurons 3 11 47177525-47186443 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039480, HPA043904 Approved Supported Plasma membrane
Cytosol Tissue enhanced 0 skeletal muscle: 164.2 heart muscle: 89.5 -TTC7B TTC7L1 ENSG00000165914 Tetratricopeptide repeat domain 7B 14 90524564-90816479 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058363, HPA059577 Supported Supported Plasma membrane Expressed in all cerebral cortex: 72.8 -SLC39A13 FLJ25785 ENSG00000165915 Solute carrier family 39 (zinc transporter), member 13 11 47407132-47416501 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA043971 Approved Uncertain Cytosol Expressed in all placenta: 58.0 -PSMC3 TBP-1, TBP1 ENSG00000165916 Proteasome 26S subunit, ATPase 3 11 47418769-47426473 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006065 Approved Supported Nucleus
Cytosol Expressed in all parathyroid gland: 117.3 -RAPSN CMS1D, CMS1E, RNF205 ENSG00000165917 Receptor-associated protein of the synapse 11 47437757-47449178 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039475 Approved Approved Plasma membrane
Centrosome
Cytosol Tissue enriched 10 skeletal muscle: 30.0 placenta: 2.9 -AGBL2 CCP2, FLJ23598 ENSG00000165923 ATP/GTP binding protein-like 2 11 47659591-47715389 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007718 Uncertain Group enriched 7 fallopian tube: 15.2;testis: 22.4 epididymis: 2.8 -TC2N C14orf47, C2CD1, FLJ36557, MTAC2D1, Tac2-N ENSG00000165929 Tandem C2 domains, nuclear 14 91779751-91867536 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027549 Approved Approved Nucleoplasm
Nuclear bodies Mixed parathyroid gland: 39.8 -CPSF2 KIAA1367 ENSG00000165934 Cleavage and polyadenylation specific factor 2, 100kDa 14 92121937-92172145 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024238 Supported Approved Nucleoplasm
Vesicles Expressed in all testis: 47.6 -SMCO2 C12orf70, LOC341346 ENSG00000165935 Single-pass membrane protein with coiled-coil domains 2 12 27466810-27502185 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014366 Uncertain Tissue enhanced 0 testis: 1.3 skin: 0.6 -MOAP1 MAP-1, PNMA4 ENSG00000165943 Modulator of apoptosis 1 14 93182196-93184928 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA000939 Uncertain Approved Nucleus
Cell Junctions Expressed in all cerebral cortex: 86.4 -IFI27L1 FAM14B ENSG00000165948 Interferon, alpha-inducible protein 27-like 1 14 94081282-94103846 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 71.8 ovary: 27.4 -IFI27 FAM14D, ISG12, P27 ENSG00000165949 Interferon, alpha-inducible protein 27 14 94104836-94116698 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA028875 Uncertain Expressed in all spleen: 743.8 -SERPINA12 OL-64, Vaspin ENSG00000165953 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 14 94487274-94517844 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 10 skin: 349.7 breast: 35.1 -CLMN FLJ12383, KIAA0500, KIAA1188 ENSG00000165959 Calmin (calponin-like, transmembrane) 14 95181940-95319906 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012634 Approved Approved Nuclear bodies
Cytosol Tissue enhanced 0 testis: 48.6 kidney: 14.8 -PDZRN4 DKFZp434B0417, FLJ33777, IMAGE5767589, LNX4 ENSG00000165966 PDZ domain containing ring finger 4 12 41188448-41574590 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039510 Uncertain Tissue enhanced 0 seminal vesicle: 19.4 prostate: 8.8 -SLC6A5 GLYT2, NET1 ENSG00000165970 Solute carrier family 6 (neurotransmitter transporter), member 5 11 20599400-20659285 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lung: 1.4 testis: 0.6 -CCDC38 FLJ40089 ENSG00000165972 Coiled-coil domain containing 38 12 95867048-95942974 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039726 Approved Nucleus
Nucleoli Tissue enriched 18 testis: 26.2 liver: 1.4 -NELL1 FLJ45906, IDH3GL ENSG00000165973 Neural EGFL like 1 11 20669551-21575681 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051535 Approved Tissue enhanced 0 cerebral cortex: 22.9;kidney: 18.6 prostate: 8.2 -PTER ENSG00000165983 Phosphotriesterase related 10 16436943-16513745 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038044, HPA038045 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 42.9 -C1QL3 C1ql, C1QTNF13, CTRP13, K100 ENSG00000165985 Complement component 1, q subcomponent-like 3 10 16513743-16522005 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 20 cerebral cortex: 43.5 kidney: 2.2 -CACNB2 CACNLB2, MYSB ENSG00000165995 Calcium channel, voltage-dependent, beta 2 subunit 10 18140677-18541869 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035325, HPA035326 Uncertain Mixed cerebral cortex: 26.4 -HACD1 CAP, PTPLA ENSG00000165996 3-hydroxyacyl-CoA dehydratase 1 10 17589032-17617377 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed heart muscle: 40.1 -ARL5B ARL8 ENSG00000165997 ADP-ribosylation factor-like 5B 10 18659405-18681639 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027002 Approved Mixed adrenal gland: 28.1 -SMCO4 C11orf75, FN5 ENSG00000166002 Single-pass membrane protein with coiled-coil domains 4 11 93478472-93543508 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041120 Uncertain Expressed in all salivary gland: 98.0 -CEP295 KIAA1731 ENSG00000166004 Centrosomal protein 295kDa 11 93661639-93730358 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038595, HPA038596, HPA038597 Approved Supported Plasma membrane
Cytosol Expressed in all testis: 22.2 -KCNC2 Kv3.2 ENSG00000166006 Potassium channel, voltage gated Shaw related subfamily C, member 2 12 75040077-75209868 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019664, CAB022571 Uncertain Supported Plasma membrane
Cytosol Tissue enriched 11 cerebral cortex: 46.5 prostate: 4.2 -TAF1D JOSD3, MGC5306, TAF(I)41 ENSG00000166012 TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 11 93729948-93784391 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055935, HPA060385 Uncertain Supported Nucleoplasm
Microtubule organizing center Expressed in all placenta: 14.0 -ABTB2 ABTB2A, BTBD22, DKFZP586C1619 ENSG00000166016 Ankyrin repeat and BTB (POZ) domain containing 2 11 34150988-34358008 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA020065, HPA030699 Approved Supported Nucleus Mixed adrenal gland: 13.1 -R3HCC1L C10orf28, GIDRP86, PSORT ENSG00000166024 R3H domain and coiled-coil containing 1-like 10 98134624-98244897 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037367 Approved Approved Nucleoplasm
Nuclear speckles Expressed in all testis: 38.7 -AMOTL1 JEAP ENSG00000166025 Angiomotin like 1 11 94706431-94876753 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001196 Approved Supported Cell Junctions
Cytosol Expressed in all prostate: 52.2 -HTRA1 ARMD7, HtrA, IGFBP5-protease, PRSS11 ENSG00000166033 HtrA serine peptidase 1 10 122461525-122514908 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036655 Approved Supported Plasma membrane Mixed ovary: 502.5 -LIPC HL, HTGL ENSG00000166035 Lipase, hepatic 15 58410569-58569843 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 14 liver: 86.4 kidney: 6.3 -CEP57 KIAA0092, Translokin, TSP57 ENSG00000166037 Centrosomal protein 57kDa 11 95789965-95832693 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018315 Approved Supported Microtubules
Cytosol Expressed in all testis: 53.8 -TCP11L2 MGC40368 ENSG00000166046 T-complex 11, testis-specific-like 2 12 106301929-106347015 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039483, HPA042188 Uncertain Supported Nuclear speckles Expressed in all fallopian tube: 26.2 -PASD1 CT63 ENSG00000166049 PAS domain containing 1 X 151563622-151676739 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011122, HPA011152 Supported Supported Nuclear speckles Tissue enriched 297 testis: 29.7 epididymis: 0.0 -SPRED1 FLJ33903, PPP1R147 ENSG00000166068 Sprouty-related, EVH1 domain containing 1 15 38252326-38357249 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042193, HPA061805 Approved Supported Nucleus Mixed thyroid gland: 48.1 -TMCO5A MGC35118, TMCO5 ENSG00000166069 Transmembrane and coiled-coil domains 5A 15 37921939-37967724 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA056530 Supported Tissue enriched 177 testis: 122.1 fallopian tube: 0.6 -GPR176 Gm1012 ENSG00000166073 G protein-coupled receptor 176 15 39799023-39920892 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039943, HPA039979 Approved Mixed cerebral cortex: 19.1 -JAM3 JAM-C, JAMC ENSG00000166086 Junctional adhesion molecule 3 11 134068925-134152001 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003417, HPA050434 Uncertain Validated Golgi apparatus Expressed in all placenta: 143.3 -IL25 IL-17E, IL-25, IL17E ENSG00000166090 Interleukin 25 14 23372809-23376403 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level CAB024864 Approved Not detected testis: 0.3 -CMTM5 CKLFSF5, FLJ37521 ENSG00000166091 CKLF-like MARVEL transmembrane domain containing 5 14 23376808-23379772 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052338 Supported Tissue enriched 20 cerebral cortex: 81.5 bone marrow: 4.0 -GLB1L3 FLJ90231 ENSG00000166105 Galactosidase, beta 1-like 3 11 134274245-134319564 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039916 Uncertain Tissue enhanced 0 prostate: 18.8;seminal vesicle: 10.7 cerebral cortex: 4.0 -ADAMTS15 ENSG00000166106 ADAM metallopeptidase with thrombospondin type 1 motif, 15 11 130448974-130476641 Enzymes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042867 Uncertain Approved Cytosol Tissue enhanced 0 adipose tissue: 30.2;placenta: 23.5 breast: 11.0 -SVOP DKFZp761H039 ENSG00000166111 SV2 related protein 12 108907741-109021240 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA016573 Uncertain Tissue enriched 15 cerebral cortex: 32.4 adrenal gland: 2.1 -SPATA19 CT132, FLJ25851, SPAS1, spergen1 ENSG00000166118 Spermatogenesis associated 19 11 133840631-133845538 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040082 Supported Tissue enriched 503 testis: 141.9 esophagus: 0.2 -GPT2 ALT2 ENSG00000166123 Glutamic pyruvate transaminase (alanine aminotransferase) 2 16 46884378-46931297 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051514 Approved Approved Mitochondria Expressed in all esophagus: 85.4 -AMN amnionless ENSG00000166126 Amnion associated transmembrane protein 14 102922656-102933596 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000817 Approved Group enriched 6 colon: 20.4;duodenum: 35.1;kidney: 29.0;small intestine: 72.0 liver: 6.8 -RAB8B ENSG00000166128 RAB8B, member RAS oncogene family 15 63189469-63267782 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA074534 Supported Nucleoplasm
Vesicles Expressed in all bone marrow: 50.7 -IKBIP FLJ31051, IKIP ENSG00000166130 IKBKB interacting protein 12 98613405-98645113 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038677, HPA038678, HPA061541 Approved Validated Endoplasmic reticulum Mixed placenta: 36.3 -RPUSD2 C15orf19, C18B11, FLJ31409 ENSG00000166133 RNA pseudouridylate synthase domain containing 2 15 40569300-40574943 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042079, HPA042194 Approved Approved Nucleoplasm
Microtubules Mixed lymph node: 7.8 -HIF1AN DKFZp762F1811, FIH1, FLJ20615, FLJ22027 ENSG00000166135 Hypoxia inducible factor 1, alpha subunit inhibitor 10 100529072-100559998 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048742, HPA065302, CAB069903 Supported Supported Nucleoplasm
Cytosol Expressed in all testis: 25.7 -NDUFB8 ASHI, CI-ASHI ENSG00000166136 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 10 100523740-100530000 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003886 Supported Supported Mitochondria Expressed in all heart muscle: 292.4 -ZFYVE19 ANCHR, FLJ14840 ENSG00000166140 Zinc finger, FYVE domain containing 19 15 40807086-40815084 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040283, HPA041946 Uncertain Expressed in all parathyroid gland: 27.7 -PPP1R14D CPI17-like, FLJ20251, GBPI-1, MGC119014, MGC119016 ENSG00000166143 Protein phosphatase 1, regulatory (inhibitor) subunit 14D 15 40815445-40828709 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041846 Uncertain Group enriched 7 colon: 107.5;duodenum: 114.3;gallbladder: 24.3;rectum: 101.6;small intestine: 91.7 appendix: 12.9 -SPINT1 HAI, MANSC2 ENSG00000166145 Serine peptidase inhibitor, Kunitz type 1 15 40844018-40858207 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006903 Uncertain Uncertain Plasma membrane
Cytosol Mixed parathyroid gland: 219.8 -FBN1 FBN, MASS, MFS1, OCTD, SGS, WMS ENSG00000166147 Fibrillin 1 15 48408306-48645849 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002670, HPA017759, HPA021057, CAB058696, CAB068188 Supported Approved Cytosol Tissue enhanced 0 placenta: 106.6 adipose tissue: 70.1 -AVPR1A AVPR1 ENSG00000166148 Arginine vasopressin receptor 1A 12 63142759-63150942 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adrenal gland: 78.3 adipose tissue: 19.9 -C16orf78 MGC33367 ENSG00000166152 Chromosome 16 open reading frame 78 16 49373823-49399431 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 347 testis: 70.4 lung: 0.2 -DEPDC4 DEP.4, FLJ33505 ENSG00000166153 DEP domain containing 4 12 100203669-100267079 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039323 Uncertain Approved Microtubules Tissue enhanced 0 testis: 7.2 kidney: 1.7 -LRTM2 ENSG00000166159 Leucine-rich repeats and transmembrane domains 2 12 1820267-1836752 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA055094 Uncertain Tissue enriched 47 cerebral cortex: 8.3 testis: 0.1 -OPN1MW2 ENSG00000166160 Opsin 1 (cone pigments), medium-wave-sensitive 2 X 154219756-154233286 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.0 -BRD7 BP75, CELTIX1 ENSG00000166164 Bromodomain containing 7 16 50313487-50368934 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042389, CAB046458, HPA060171 Supported Supported Nucleoplasm
Cytosol Expressed in all testis: 105.3 -CKB CKBB ENSG00000166165 Creatine kinase, brain 14 103519659-103523111 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001254, CAB047313 Supported Supported Cytosol Expressed in all cerebral cortex: 476.4 -TRMT61A C14orf172, FLJ40452, GCD14, Gcd14p, hTRM61 ENSG00000166166 TRNA methyltransferase 61A 14 103529184-103537073 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all seminal vesicle: 10.0 -BTRC beta-TrCP1, betaTrCP, bTrCP, bTrCP1, FBXW1A, Fwd1 ENSG00000166167 Beta-transducin repeat containing E3 ubiquitin protein ligase 10 101354033-101557321 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031156, CAB032986 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all cerebral cortex: 34.1 -POLL ENSG00000166169 Polymerase (DNA directed), lambda 10 101578882-101588270 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066704 Approved Nucleus
Golgi apparatus Expressed in all testis: 49.7 -BAG5 ENSG00000166170 BCL2-associated athanogene 5 14 103556544-103562831 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016429 Uncertain Supported Vesicles Tissue enriched 6 testis: 240.6 thyroid gland: 38.6 -DPCD DKFZP566F084, RP11-529I10.4 ENSG00000166171 Deleted in primary ciliary dyskinesia homolog (mouse) 10 101570560-101609668 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036603, HPA036604 Supported Approved Nuclear speckles Expressed in all testis: 152.7 -LARP6 acheron, FLJ11196 ENSG00000166173 La ribonucleoprotein domain family, member 6 15 70829130-70854159 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020338, HPA049029 Approved Approved Microtubules
Cytokinetic bridge Tissue enhanced 0 cerebral cortex: 84.9 thyroid gland: 40.7 -API5 AAC-11, AAC11, API5L1 ENSG00000166181 Apoptosis inhibitor 5 11 43311963-43344529 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026598 Approved Validated Nuclear speckles Expressed in all thyroid gland: 95.4 -ASPG C14orf76 ENSG00000166183 Asparaginase 14 104085679-104115581 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA069761 Approved Tissue enhanced 0 liver: 29.4 heart muscle: 18.8 -ZNF319 KIAA1388, Zfp319 ENSG00000166188 Zinc finger protein 319 16 57994668-58000453 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052584 Uncertain Approved Nucleus Mixed parathyroid gland: 13.7 -HPS6 BLOC2S3, FLJ22501 ENSG00000166189 Hermansky-Pudlak syndrome 6 10 102065390-102068038 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040687 Approved Expressed in all fallopian tube: 11.8 -SENP8 DEN1, HsT17512, NEDP1, PRSC2 ENSG00000166192 SUMO/sentrin peptidase family member, NEDD8 specific 15 72114258-72143688 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036273 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 testis: 27.8 thyroid gland: 8.5 -NOLC1 KIAA0035, NOPP130, NOPP140, P130 ENSG00000166197 Nucleolar and coiled-body phosphoprotein 1 10 102152176-102163871 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032654, HPA037366, HPA050388 Supported Validated Nucleoli Expressed in all parathyroid gland: 68.0 -ALKBH3 DEPC-1 ENSG00000166199 AlkB homolog 3, alpha-ketoglutarate-dependent dioxygenase 11 43880811-43920266 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009674, HPA046489 Approved Validated Nucleoplasm
Mitochondria Expressed in all epididymis: 31.9 -COPS2 ALIEN, CSN2, TRIP15 ENSG00000166200 COP9 signalosome subunit 2 15 49106068-49155661 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016867, HPA018271, HPA061071 Approved Validated Vesicles
Cytokinetic bridge Expressed in all thyroid gland: 103.1 -GABRB3 ENSG00000166206 Gamma-aminobutyric acid (GABA) A receptor, beta 3 15 26543546-26939539 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 80.1 gallbladder: 21.9 -SPIC MGC40611, SPI-C ENSG00000166211 Spi-C transcription factor (Spi-1/PU.1 related) 12 101475421-101486997 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12 spleen: 47.3 lymph node: 4.0 -TBATA C10orf27, FLJ32820, spatial ENSG00000166220 Thymus, brain and testes associated 10 70771239-70785401 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 26 testis: 31.9 spleen: 1.2 -SGPL1 SPL ENSG00000166224 Sphingosine-1-phosphate lyase 1 10 70815961-70881173 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021125, HPA023086 Approved Supported Endoplasmic reticulum Expressed in all skin: 34.6 -FRS2 FRS2A, FRS2alpha, SNT-1, SNT1 ENSG00000166225 Fibroblast growth factor receptor substrate 2 12 69470349-69579789 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038323 Approved Cell Junctions Expressed in all parathyroid gland: 27.0 -CCT2 Cctb ENSG00000166226 Chaperonin containing TCP1, subunit 2 (beta) 12 69585334-69601570 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003197, HPA003198 Supported Supported Cytosol Expressed in all testis: 365.6 -PCBD1 DCOH, PCBD, PCD ENSG00000166228 Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 10 70882280-70888784 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037575, HPA061723 Approved Validated Nucleoplasm
Cytosol Expressed in all liver: 157.2 -ARIH1 ARI, HARI, HHARI, UBCH7BP ENSG00000166233 Ariadne RBR E3 ubiquitin protein ligase 1 15 72474326-72602985 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003295, HPA073245 Approved Approved Nucleus
Golgi apparatus Expressed in all testis: 65.3 -C16orf71 DKFZp686H2240, FLJ43261 ENSG00000166246 Chromosome 16 open reading frame 71 16 4734272-4749396 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049468 Supported Uncertain Nuclear speckles Group enriched 16 fallopian tube: 36.2;testis: 113.1 epididymis: 4.5 -CLMP ACAM, ASAM, FLJ22415 ENSG00000166250 CXADR-like membrane protein 11 123069865-123195281 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed adipose tissue: 65.1 -SCN3B HSA243396 ENSG00000166257 Sodium channel, voltage gated, type III beta subunit 11 123629187-123655244 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042518 Approved Nuclear membrane
Cytokinetic bridge Tissue enriched 11 cerebral cortex: 132.5 adrenal gland: 11.6 -COX11 COX11P ENSG00000166260 COX11 cytochrome c oxidase copper chaperone 17 54951902-54968785 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044020 Approved Expressed in all duodenum: 62.9 -ZNF202 ZKSCAN10, ZSCAN42 ENSG00000166261 Zinc finger protein 202 11 123724177-123741675 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061946 Supported Nucleoplasm
Mitochondria Expressed in all testis: 16.7 -FAM227B C15orf33, FLJ32800 ENSG00000166262 Family with sequence similarity 227, member B 15 49326962-49620931 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049774, HPA061695 Uncertain Approved Nuclear speckles Expressed in all testis: 21.3 -STXBP4 MGC50337, Synip ENSG00000166263 Syntaxin binding protein 4 17 54968727-55173632 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB007760, HPA022138, HPA022888, HPA024227 Approved Approved Plasma membrane
Cytosol Mixed parathyroid gland: 12.2 -CYYR1 C21orf95 ENSG00000166265 Cysteine/tyrosine-rich 1 21 26466209-26573284 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB034921, HPA067685 Uncertain Approved Nucleoplasm Expressed in all adrenal gland: 60.4 -CUL5 VACM-1 ENSG00000166266 Cullin 5 11 108008733-108107776 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002185, CAB017787 Approved Approved Golgi apparatus
Cytosol Expressed in all parathyroid gland: 25.5 -MYRFL bcm1377, C12orf15, C12orf28, FLJ25056 ENSG00000166268 Myelin regulatory factor-like 12 69825304-69959097 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049340 Approved Approved Nucleoli Group enriched 6 duodenum: 24.4;small intestine: 24.5 testis: 4.3 -WBP1L C10orf26, FLJ20154, OPAL1 ENSG00000166272 WW domain binding protein 1-like 10 102743970-102816267 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA037635, HPA038371 Uncertain Approved Nucleoplasm
Microtubules Expressed in all thyroid gland: 69.6 -BORCS7 C10orf32, FLJ40752 ENSG00000166275 BLOC-1 related complex subunit 7 10 102854223-102864961 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA037648 Approved Approved Nuclear speckles
Cytosol Expressed in all thyroid gland: 91.2 -C2 ENSG00000166278 Complement component 2 6 31897785-31945672 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016775 Supported Tissue enhanced 0 liver: 86.1;lung: 42.6 placenta: 21.7 -PLEKHF1 APPD, MGC4090, PHAFIN1, ZFYVE15 ENSG00000166289 Pleckstrin homology domain containing, family F (with FYVE domain) member 1 19 29665056-29675457 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025925 Uncertain Mixed skeletal muscle: 18.7 -TMEM100 FLJ10970, FLJ37856 ENSG00000166292 Transmembrane protein 100 17 55719627-55732121 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055936 Approved Tissue enhanced 0 lung: 131.4;placenta: 77.5 epididymis: 44.0 -ANAPC16 APC16, bA570G20.3, C10orf104, CENP-27, FLJ33728 ENSG00000166295 Anaphase promoting complex subunit 16 10 72216000-72235860 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037815 Approved Supported Cytosol Expressed in all thyroid gland: 40.3 -SMPD1 ASM ENSG00000166311 Sphingomyelin phosphodiesterase 1, acid lysosomal 11 6390431-6394998 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 62.3 -APBB1 Fe65, RIR ENSG00000166313 Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 11 6395124-6419414 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022104, HPA038521, HPA038522 Approved Validated Plasma membrane Expressed in all cerebral cortex: 237.2 -SYNPO2L FLJ12921 ENSG00000166317 Synaptopodin 2-like 10 73644881-73663803 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055192, HPA057142 Supported Approved Nuclear speckles
Cell Junctions
Cytosol Group enriched 11 heart muscle: 158.4;skeletal muscle: 96.0 esophagus: 11.2 -NUDT13 DKFZp586P2219 ENSG00000166321 Nudix (nucleoside diphosphate linked moiety X)-type motif 13 10 73110375-73131828 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040636 Approved Approved Nucleus Mixed epididymis: 6.2 -C11orf65 MGC33948 ENSG00000166323 Chromosome 11 open reading frame 65 11 108308519-108467531 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 27 testis: 93.5 epididymis: 3.4 -TRIM44 DIPB, MC7 ENSG00000166326 Tripartite motif containing 44 11 35662805-35818007 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049053, HPA057633 Approved Approved Vesicles
Plasma membrane Expressed in all cerebral cortex: 30.8 -CCDC182 ENSG00000166329 Coiled-coil domain containing 182 17 57744481-57745312 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023446 Uncertain Tissue enriched 212 testis: 21.1 adipose tissue: 0.0 -ILK ENSG00000166333 Integrin-linked kinase 11 6603708-6610874 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004041, HPA048437 Supported Validated Cell Junctions
Focal adhesion sites Expressed in all seminal vesicle: 554.5 -TAF10 TAF2A, TAF2H, TAFII30 ENSG00000166337 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 11 6606296-6612667 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004148, CAB022405 Supported Supported Nucleus Expressed in all testis: 132.4 -TPP1 CLN2, SCAR7 ENSG00000166340 Tripeptidyl peptidase I 11 6612763-6619461 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037709, HPA044868 Supported Expressed in all spleen: 210.1 -DCHS1 CDH25, CDHR6, FIB1, FLJ11790, KIAA1773, PCDH16 ENSG00000166341 Dachsous cadherin-related 1 11 6621323-6655854 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017970, HPA050246 Approved Approved Plasma membrane Mixed endometrium: 29.5 -NETO1 BCTL1, BTCL1 ENSG00000166342 Neuropilin (NRP) and tolloid (TLL)-like 1 18 72742314-72868146 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA064630 Approved Golgi apparatus Tissue enriched 15 cerebral cortex: 64.1 spleen: 4.1 -MSS51 FLJ39565, ZMYND17 ENSG00000166343 MSS51 mitochondrial translational activator 10 73423579-73433561 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038564, HPA038566 Uncertain Uncertain Vesicles
Cytosol Group enriched 18 parathyroid gland: 159.7;skeletal muscle: 81.4 heart muscle: 6.7 -CYB5A CYB5 ENSG00000166347 Cytochrome b5 type A (microsomal) 18 74250847-74292016 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006333, HPA047548, HPA058547 Supported Approved Vesicles
Cytosol Expressed in all liver: 1254.1 -USP54 bA137L10.3, bA137L10.4, C10orf29, FLJ37318 ENSG00000166348 Ubiquitin specific peptidase 54 10 73497538-73625953 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047663 Approved Approved Mitochondria Tissue enhanced 0 thyroid gland: 66.5 cerebral cortex: 33.1 -RAG1 MGC43321, RNF74 ENSG00000166349 Recombination activating gene 1 11 36510709-36593156 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 thyroid gland: 4.2 spleen: 3.7 -POTED A26B3, ANKRD21, CT104.1, POTE, POTE-21, POTE21 ENSG00000166351 POTE ankyrin domain family, member D 21 13609858-13641585 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042822 Uncertain Tissue enriched 14 testis: 1.3 epididymis: 0.0 -C11orf74 FLJ38678, HEPIS ENSG00000166352 Chromosome 11 open reading frame 74 11 36594493-36659290 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044880 Uncertain Approved Aggresome
Cytosol Expressed in all thyroid gland: 177.0 -WDR88 PQWD ENSG00000166359 WD repeat domain 88 19 33132090-33175795 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041916, HPA050336 Uncertain Approved Nucleoplasm
Golgi apparatus Tissue enriched 6 testis: 11.3 thyroid gland: 1.9 -OR10A5 JCG6, OR10A1, OR11-403 ENSG00000166363 Olfactory receptor, family 10, subfamily A, member 5 11 6845652-6846705 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -OR2D2 hg27, OR11-610, OR2D1 ENSG00000166368 Olfactory receptor, family 2, subfamily D, member 2 11 6891490-6892599 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -ATP9B ATPIIB ENSG00000166377 ATPase, class II, type 9B 18 79069285-79378283 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029364 Approved Expressed in all testis: 39.0 -PPFIBP2 Cclp1 ENSG00000166387 PTPRF interacting protein, binding protein 2 (liprin beta 2) 11 7513298-7657127 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001935, HPA003911 Approved Approved Mitochondria Expressed in all parathyroid gland: 184.4 -MOGAT2 DGAT2L5, FLJ22644, MGAT2 ENSG00000166391 Monoacylglycerol O-acyltransferase 2 11 75717819-75732958 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028834 Uncertain Group enriched 12 colon: 12.7;duodenum: 38.2;liver: 12.1;rectum: 12.7;small intestine: 44.5 appendix: 2.0 -CYB5R2 ENSG00000166394 Cytochrome b5 reductase 2 11 7665100-7677222 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038962 Approved Approved Nucleoplasm
Golgi apparatus Tissue enhanced 0 testis: 226.8 parathyroid gland: 78.3 -SERPINB7 MEGSIN ENSG00000166396 Serpin peptidase inhibitor, clade B (ovalbumin), member 7 18 63752935-63805376 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024200 Approved Approved Endoplasmic reticulum
Mitochondria Tissue enhanced 0 skin: 123.8;tonsil: 35.5 breast: 17.2 -KIAA0355 ENSG00000166398 KIAA0355 19 34254537-34355586 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014570 Uncertain Approved Nucleoplasm Expressed in all placenta: 33.0 -SERPINB8 CAP2, PI8 ENSG00000166401 Serpin peptidase inhibitor, clade B (ovalbumin), member 8 18 63969925-64005667 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034300 Approved Approved Nucleus
Cytosol Mixed skin: 48.0 -TUB rd5 ENSG00000166402 Tubby bipartite transcription factor 11 8019244-8106112 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017997, HPA049019 Uncertain Approved Nucleoli
Microtubule organizing center
Centrosome Mixed cerebral cortex: 51.5 -RIC3 AYST720, FLJ11608, PRO1385 ENSG00000166405 RIC3 acetylcholine receptor chaperone 11 8106093-8169055 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA065016 Approved Mixed parathyroid gland: 27.9 -LMO1 RBTN1, RHOM1, TTG1 ENSG00000166407 LIM domain only 1 (rhombotin 1) 11 8224304-8268716 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skeletal muscle: 10.1;skin: 5.9 testis: 2.0 -IDH3A ENSG00000166411 Isocitrate dehydrogenase 3 (NAD+) alpha 15 78131498-78171949 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041465, HPA062971 Supported Validated Mitochondria Expressed in all cerebral cortex: 44.3 -WDR72 FLJ38736 ENSG00000166415 WD repeat domain 72 15 53513741-53762878 Disease related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048212, HPA057410, HPA059819 Uncertain Approved Vesicles Group enriched 6 kidney: 103.9;thyroid gland: 91.7 liver: 17.1 -CRABP1 CRABP, CRABP-I, CRABPI, RBP5 ENSG00000166426 Cellular retinoic acid binding protein 1 15 78340324-78348230 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017203 Approved Tissue enhanced 0 thyroid gland: 267.9 seminal vesicle: 63.7 -PLD4 C14orf175 ENSG00000166428 Phospholipase D family, member 4 14 104924816-104937790 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051512 Approved Mixed lymph node: 14.1 -ZMAT1 KIAA1789 ENSG00000166432 Zinc finger, matrin-type 1 X 101882288-101932031 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA012827 Uncertain Approved Nucleoplasm Tissue enhanced 0 epididymis: 25.5 parathyroid gland: 12.0 -XRRA1 FLJ00225 ENSG00000166435 X-ray radiation resistance associated 1 11 74807739-74949200 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039263 Supported Nucleoplasm
Nuclear bodies Tissue enhanced 0 testis: 35.7 thyroid gland: 11.7 -TRIM66 C11orf29, KIAA0298, TIF1D ENSG00000166436 Tripartite motif containing 66 11 8612037-8671866 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA027420 Approved Supported Nucleoplasm Mixed testis: 14.1 -RNF169 KIAA1991 ENSG00000166439 Ring finger protein 169 11 74748868-74842413 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046138, HPA058368 Uncertain Supported Nuclear speckles Mixed parathyroid gland: 14.9 -RPL27A L27A ENSG00000166441 Ribosomal protein L27a 11 8682411-8714759 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060776, HPA063379 Supported Supported Endoplasmic reticulum
Cytosol Expressed in all lymph node: 2865.3 -ST5 DENND2B, HTS1, p126 ENSG00000166444 Suppression of tumorigenicity 5 11 8693351-8910951 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046796 Approved Approved Nucleoplasm Expressed in all endometrium: 190.3 -CDYL2 FLJ38866 ENSG00000166446 Chromodomain protein, Y-like 2 16 80597906-80804329 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041016 Approved Mixed testis: 21.3 -TMEM130 DKFZp761L1417, FLJ42643 ENSG00000166448 Transmembrane protein 130 7 98846488-98870771 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA012928 Uncertain Supported Golgi apparatus Group enriched 9 adrenal gland: 49.3;cerebral cortex: 183.7;testis: 70.8 epididymis: 11.5 -PRTG FLJ25756, IGDCC5 ENSG00000166450 Protogenin 15 55611546-55743090 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA032138 Uncertain Approved Vesicles
Plasma membrane
Cytosol Tissue enhanced 0 thyroid gland: 18.2 testis: 6.7 -CENPN BM039, C16orf60, FLJ13607, FLJ22660 ENSG00000166451 Centromere protein N 16 81006498-81033114 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052870 Supported Nucleus Expressed in all prostate: 26.7 -AKIP1 BCA3, C11orf17 ENSG00000166452 A kinase (PRKA) interacting protein 1 11 8911139-8920084 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061391 Supported Nucleoplasm Expressed in all adrenal gland: 30.7 -ATMIN ASCIZ, KIAA0431, ZNF822 ENSG00000166454 ATM interactor 16 81035847-81047358 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA054967, HPA066900 Approved Supported Nuclear bodies Expressed in all parathyroid gland: 60.2 -C16orf46 FLJ32702 ENSG00000166455 Chromosome 16 open reading frame 46 16 81053497-81077267 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA041136, HPA041379 Uncertain Supported Nucleoplasm
Cytosol Tissue enhanced 0 testis: 16.3;thyroid gland: 12.4 fallopian tube: 8.8 -TMEM41B KIAA0033 ENSG00000166471 Transmembrane protein 41B 11 9280654-9314780 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014946 Uncertain Approved Peroxisomes Mixed thyroid gland: 22.3 -LEO1 ENSG00000166477 LEO1 homolog, Paf1/RNA polymerase II complex component 15 51938025-51971806 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040741, HPA040941 Supported Validated Nucleoplasm
Nucleoli fibrillar center Expressed in all parathyroid gland: 35.1 -ZNF143 pHZ-1, SBF, STAF ENSG00000166478 Zinc finger protein 143 11 9460319-9528524 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003263, HPA074818 Supported Approved Nucleoplasm
Nuclear bodies
Vesicles Expressed in all testis: 31.5 -TMX3 FLJ20793, KIAA1830, PDIA13, TXNDC10 ENSG00000166479 Thioredoxin-related transmembrane protein 3 18 68673688-68715298 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014157 Uncertain Expressed in all appendix: 32.3 -MFAP4 ENSG00000166482 Microfibrillar-associated protein 4 17 19383442-19387240 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054097 Supported Approved Endoplasmic reticulum Expressed in all gallbladder: 976.6 -WEE1 WEE1A ENSG00000166483 WEE1 G2 checkpoint kinase 11 9573681-9593457 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004619, HPA068845 Approved Approved Nucleoli Expressed in all endometrium: 89.6 -MAPK7 BMK1, ERK5, PRKM7 ENSG00000166484 Mitogen-activated protein kinase 7 17 19377721-19383544 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018561, HPA031031 Uncertain Validated Nucleus
Cytosol Mixed testis: 10.7 -PRKCB PKCB, PRKCB1, PRKCB2 ENSG00000166501 Protein kinase C, beta 16 23836001-24220611 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003843, HPA048321, HPA054203 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 125.8 spleen: 65.5 -RP11-382A20.3 ENSG00000166503 Hepatoma-derived growth factor-related protein 3 15 83112738-83208018 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040719 Approved Supported Nucleoplasm Tissue enhanced 0 parathyroid gland: 33.0 cerebral cortex: 19.6 -NDST2 HSST2, NST2 ENSG00000166507 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 10 73801911-73811798 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051515 Approved Approved Cytosol Expressed in all spleen: 44.9 -MCM7 CDC47, MCM2, PPP1R104 ENSG00000166508 Minichromosome maintenance complex component 7 7 100092728-100101940 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002163, HPA003898, CAB016312 Supported Validated Nucleoplasm Expressed in all lymph node: 41.9 -CLEC3A CLECSF1 ENSG00000166509 C-type lectin domain family 3, member A 16 78022515-78066761 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051511 Uncertain Tissue enhanced 0 breast: 12.2;urinary bladder: 8.5 prostate: 3.0 -CCDC68 SE57-1 ENSG00000166510 Coiled-coil domain containing 68 18 54901509-54959508 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040865, HPA048197 Supported Approved Golgi apparatus
Cytosol Tissue enhanced 0 placenta: 45.8 small intestine: 27.8 -CLEC4E CLECSF9, mincle ENSG00000166523 C-type lectin domain family 4, member E 12 8533305-8540963 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA004935 Uncertain Uncertain Cytosol Tissue enhanced 0 appendix: 55.1;bone marrow: 49.8;spleen: 44.9 gallbladder: 19.0 -ZNF3 A8-51, FLJ20216, HF.12, KOX25, PP838, Zfp113 ENSG00000166526 Zinc finger protein 3 7 100064033-100082548 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003719 Supported Approved Approved Nucleoplasm Expressed in all fallopian tube: 55.2 -CLEC4D CD368, CLECSF8, Mpcl ENSG00000166527 C-type lectin domain family 4, member D 12 8509475-8522366 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004906 Approved Group enriched 6 appendix: 10.7;bone marrow: 42.9 cervix: 4.8 -ZSCAN21 DKFZp434L134, NY-REN-21, Zipro1, ZNF38 ENSG00000166529 Zinc finger and SCAN domain containing 21 7 100049774-100065038 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA016948, HPA023591 Uncertain Approved Endoplasmic reticulum Expressed in all testis: 20.5 -RIMKLB FAM80B, KIAA1238, NAAGS, NAAGS-I ENSG00000166532 Ribosomal modification protein rimK-like family member B 12 8681600-8783095 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA059552 Approved Nucleoplasm
Microtubule organizing center Expressed in all endometrium: 74.3 -A2ML1 CPAMD9, FLJ25179 ENSG00000166535 Alpha-2-macroglobulin-like 1 12 8822472-8887001 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038847, HPA038848 Supported Tissue enriched 6 esophagus: 480.8 skin: 85.7 -BEAN1 SCA31 ENSG00000166546 Brain expressed, associated with NEDD4, 1 16 66427297-66493529 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053851 Uncertain Uncertain Nucleoplasm
Centrosome Mixed cerebral cortex: 2.2 -TK2 SCA31 ENSG00000166548 Thymidine kinase 2, mitochondrial 16 66508003-66552544 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041162 Uncertain Expressed in all parathyroid gland: 88.2 -TMED3 C15orf22, p24B, p24g4, p24gamma4 ENSG00000166557 Transmembrane p24 trafficking protein 3 15 79311062-79427432 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049314, HPA076949 Approved Supported Golgi apparatus Mixed salivary gland: 164.3 -SLC38A8 ENSG00000166558 Solute carrier family 38, member 8 16 84009667-84042636 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Not detected testis: 0.9 -SEC11C SEC11L3, SPC21, SPCS4C ENSG00000166562 SEC11 homolog C, signal peptidase complex subunit 18 59139477-59158836 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026816, HPA047533 Approved Approved Nuclear membrane
Golgi apparatus Expressed in all prostate: 275.4 -CPLX4 CPX-IV ENSG00000166569 Complexin 4 18 59275156-59318649 Predicted intracellular proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected testis: 0.4 -GALR1 GALNR, GALNR1 ENSG00000166573 Galanin receptor 1 18 77250549-77277896 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adrenal gland: 2.1;cerebral cortex: 1.7 testis: 0.5 -TMEM135 FLJ22104 ENSG00000166575 Transmembrane protein 135 11 87037844-87323758 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA056685, HPA069473 Uncertain Supported Vesicles Expressed in all adipose tissue: 31.8 -IQCD CFAP84, DRC10 ENSG00000166578 IQ motif containing D 12 113195441-113221094 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046810, HPA048782 Uncertain Approved Nucleus Group enriched 6 fallopian tube: 34.5;testis: 65.3 parathyroid gland: 7.7 -NDEL1 MITAP1, NDE1L1, NDE2, NUDEL ENSG00000166579 NudE neurodevelopment protein 1-like 1 17 8413131-8490411 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017916 Approved Expressed in all adrenal gland: 81.9 -CENPV CENP-V, p30, PRR6 ENSG00000166582 Centromere protein V 17 16342534-16353656 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042529, HPA042616 Supported Supported Nucleoplasm
Cytosol Mixed testis: 13.3 -CDH16 ENSG00000166589 Cadherin 16, KSP-cadherin 16 66908122-66918984 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB013526, HPA036260 Supported Group enriched 8 kidney: 230.2;thyroid gland: 57.6 fallopian tube: 16.9 -RRAD RAD, REM3 ENSG00000166592 Ras-related associated with diabetes 16 66921679-66925644 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041755 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Tissue enhanced 0 heart muscle: 104.7 skeletal muscle: 67.5 -FAM96B CGI-128, MIP18 ENSG00000166595 Family with sequence similarity 96, member B 16 66932055-66934423 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041501, HPA041736 Supported Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 120.4 -CFAP52 FLJ37528, WDR16, WDRPUH ENSG00000166596 Cilia and flagella associated protein 52 17 9576627-9643459 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023247 Supported Group enriched 8 fallopian tube: 91.1;testis: 22.0 lung: 6.9 -HSP90B1 GP96, GRP94, TRA1 ENSG00000166598 Heat shock protein 90kDa beta (Grp94), member 1 12 103930107-103953645 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003901, CAB005224, HPA008424 Supported Validated Endoplasmic reticulum Expressed in all thyroid gland: 2376.1 -MC4R ENSG00000166603 Melanocortin 4 receptor 18 60371110-60372775 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA016719 Uncertain Group enriched 10 cerebral cortex: 3.0;fallopian tube: 5.0 epididymis: 0.4 -BLCAP BC10 ENSG00000166619 Bladder cancer associated protein 20 37492472-37527931 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047390 Approved Nucleoli Expressed in all fallopian tube: 221.5 -SERPINB12 YUKOPIN ENSG00000166634 Serpin peptidase inhibitor, clade B (ovalbumin), member 12 18 63556160-63567011 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 5 skin: 78.4 esophagus: 15.2 -CHRFAM7A CHRNA7-DR1, D-10 ENSG00000166664 CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 15 30357766-30393849 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 6.1 parathyroid gland: 4.9 -ATF7IP2 FLJ12668 ENSG00000166669 Activating transcription factor 7 interacting protein 2 16 10326434-10483638 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041156, HPA041228 Approved Tissue enhanced 0 testis: 35.6 lymph node: 10.5 -MMP10 STMY2 ENSG00000166670 Matrix metallopeptidase 10 11 102770503-102780628 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002159 Uncertain Approved Plasma membrane
Cytosol Tissue enriched 39 endometrium: 443.1 appendix: 11.3 -TVP23A FAM18A, YDR084C ENSG00000166676 Trans-golgi network vesicle protein 23 homolog A (S. cerevisiae) 16 10760919-10818794 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060582 Uncertain Approved Vesicles Tissue enhanced 0 cerebral cortex: 6.3 ovary: 3.2 -NGFRAP1 Bex, BEX3, DXS6984E, HGR74, NADE ENSG00000166681 Nerve growth factor receptor (TNFRSF16) associated protein 1 X 103376340-103378077 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA018886 Approved Supported Cytosol Expressed in all epididymis: 599.3 -TMPRSS5 MGC141886, MGC148044 ENSG00000166682 Transmembrane protease, serine 5 11 113687550-113706373 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA010992 Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 10.1 salivary gland: 3.0 -COG1 KIAA1381, LDLB ENSG00000166685 Component of oligomeric golgi complex 1 17 73192632-73208507 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029224 Supported Expressed in all cerebral cortex: 50.9 -PLEKHA7 DKFZp686M22243 ENSG00000166689 Pleckstrin homology domain containing, family A member 7 11 16778295-17014443 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038610 Approved Supported Cell Junctions
Cytosol Mixed parathyroid gland: 38.8 -ZNF606 FLJ14260, KIAA1852, ZNF328 ENSG00000166704 Zinc finger protein 606 19 57977053-58003349 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041712, HPA043584 Uncertain Supported Nucleoplasm Expressed in all parathyroid gland: 18.9 -ZCCHC18 PNMA7B, SIZN2 ENSG00000166707 Zinc finger, CCHC domain containing 18 X 104112131-104115846 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA034940 Uncertain Tissue enhanced 0 cerebral cortex: 5.6 ovary: 4.2 -B2M ENSG00000166710 Beta-2-microglobulin 15 44711477-44718877 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002572, HPA006361 Supported Validated Golgi apparatus
Plasma membrane
Cytosol Expressed in all lymph node: 5182.5 -ZNF592 CAMOS, KIAA0211, SCAR5 ENSG00000166716 Zinc finger protein 592 15 84748635-84806432 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020332, HPA021600 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 16.5 -CASC4 DKFZp459F1927, H63 ENSG00000166734 Cancer susceptibility candidate 4 15 44288729-44415758 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043015, HPA049488 Approved Supported Golgi apparatus Expressed in all thyroid gland: 141.1 -HTR3A 5-HT3A, 5-HT3R, HTR3 ENSG00000166736 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 11 113974881-113990313 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 5 appendix: 2.9;lymph node: 7.9;tonsil: 7.4 small intestine: 1.1 -NNMT ENSG00000166741 Nicotinamide N-methyltransferase 11 114257787-114313285 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059180 Approved Approved Golgi apparatus Tissue enhanced 0 liver: 197.4 adipose tissue: 106.7 -ACSM1 BUCS1, MACS1 ENSG00000166743 Acyl-CoA synthetase medium-chain family member 1 16 20623237-20698890 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046291 Uncertain Tissue enriched 55 breast: 293.3 prostate: 5.2 -AP1G1 ADTG, CLAPG1 ENSG00000166747 Adaptor-related protein complex 1, gamma 1 subunit 16 71729000-71809201 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009049, HPA041224 Approved Validated Vesicles
Cytosol Expressed in all parathyroid gland: 87.2 -AGBL1 CCP4, FLJ32310 ENSG00000166748 ATP/GTP binding protein-like 1 15 86141996-87029052 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lung: 1.1;skeletal muscle: 2.1 esophagus: 0.6 -SLFN5 MGC19764 ENSG00000166750 Schlafen family member 5 17 35243036-35273655 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017760 Approved Approved Nucleoplasm
Vesicles Mixed lymph node: 37.9 -CATSPER2 ENSG00000166762 Cation channel, sperm associated 2 15 43628503-43668118 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 30.9 epididymis: 6.5 -C16orf45 FLJ32618 ENSG00000166780 Chromosome 16 open reading frame 45 16 15434295-15625028 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041114 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 172.4 cervix: 59.2 -KIAA0430 LKAP, Marf1, PPP1R34 ENSG00000166783 KIAA0430 16 15594386-15643166 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017992 Approved Supported Golgi apparatus
Vesicles Expressed in all parathyroid gland: 20.2 -SAAL1 FLJ41463 ENSG00000166788 Serum amyloid A-like 1 11 18069935-18106091 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039003, HPA039004 Approved Supported Nucleoplasm Expressed in all testis: 23.1 -YPEL4 FLJ30213 ENSG00000166793 Yippee-like 4 11 57645087-57649944 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045621 Uncertain Tissue enhanced 0 cerebral cortex: 19.0 ovary: 4.0 -PPIB CYPB, OI9 ENSG00000166794 Peptidylprolyl isomerase B (cyclophilin B) 15 64155812-64163205 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011487, HPA012720 Supported Supported Nucleus
Endoplasmic reticulum Expressed in all thyroid gland: 852.0 -LDHC CT32 ENSG00000166796 Lactate dehydrogenase C 11 18412307-18452058 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045442 Supported Tissue enriched 385 testis: 469.8 thyroid gland: 1.2 -FAM96A FLJ22875 ENSG00000166797 Family with sequence similarity 96, member A 15 64072559-64094018 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040459, HPA063729 Approved Supported Nucleoplasm
Cytosol Expressed in all liver: 105.8 -LDHAL6A LDH6A, MGC23940 ENSG00000166800 Lactate dehydrogenase A-like 6A 11 18455824-18479600 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 13 testis: 17.4 skin: 1.3 -FAM111A FLJ22794, KIAA1895 ENSG00000166801 Family with sequence similarity 111, member A 11 59142748-59155039 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039529, HPA040176 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all spleen: 46.3 -KIAA0101 NS5ATP9, OEATC-1, p15(PAF), PAF15 ENSG00000166803 KIAA0101 15 64364311-64387687 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047929 Supported Centrosome Tissue enhanced 0 bone marrow: 90.3;lymph node: 83.5 tonsil: 60.4 -KIF7 JBTS12 ENSG00000166813 Kinesin family member 7 15 89608789-89655451 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043145 Approved Mixed endometrium: 5.2 -LDHD ENSG00000166816 Lactate dehydrogenase D 16 75111860-75116771 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041766, HPA048639, HPA066148 Approved Approved Cytosol Mixed kidney: 33.9 -PLIN1 PLIN ENSG00000166819 Perilipin 1 15 89664365-89679427 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024299, CAB033821, CAB037333 Supported Uncertain Peroxisomes Tissue enriched 10 adipose tissue: 1011.2 breast: 99.5 -PEX11A MGC119947, MGC138534, PEX11-ALPHA ENSG00000166821 Peroxisomal biogenesis factor 11 alpha 15 89677764-89690783 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed prostate: 29.0 -TMEM170A FLJ37611, TMEM170 ENSG00000166822 Transmembrane protein 170A 16 75443054-75465497 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055071 Uncertain Expressed in all testis: 32.6 -MESP1 bHLHc5, MGC10676 ENSG00000166823 Mesoderm posterior bHLH transcription factor 1 15 89748661-89751310 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA069981 Supported Nucleus
Nucleoli Tissue enhanced 0 adipose tissue: 4.8;prostate: 4.0 cerebral cortex: 1.4 -ANPEP CD13, gp150, LAP1, p150, PEPN ENSG00000166825 Alanyl (membrane) aminopeptidase 15 89784889-89815401 CD markers, Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002417, HPA004625 Supported Supported Nucleus
Plasma membrane Group enriched 9 duodenum: 2451.4;small intestine: 2177.9 colon: 263.9 -SCNN1G ENaCgamma, SCNEG ENSG00000166828 Sodium channel, non voltage gated 1 gamma subunit 16 23182715-23216883 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA071194 Approved Nucleoplasm
Nucleoli
Plasma membrane Tissue enhanced 0 cervix, uterine: 24.5;kidney: 46.4 thyroid gland: 9.5 -RBPMS2 ENSG00000166831 RNA binding protein with multiple splicing 2 15 64739892-64775587 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 heart muscle: 149.7 seminal vesicle: 63.2 -NAV2 FLJ10633, FLJ11030, FLJ23707, HELAD1, KIAA1419, POMFIL2, RAINB1 ENSG00000166833 Neuron navigator 2 11 19350724-20121598 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011755, HPA011891 Approved Supported Nucleoplasm Mixed heart muscle: 36.5 -ANKDD1A FLJ25870 ENSG00000166839 Ankyrin repeat and death domain containing 1A 15 64911902-64958700 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040757 Approved Approved Nucleoplasm Mixed spleen: 15.6 -GLYATL1 FLJ34646, MGC15397 ENSG00000166840 Glycine-N-acyltransferase-like 1 11 58905398-59043527 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039501 Supported Uncertain Golgi apparatus
Cytosol Group enriched 13 kidney: 144.3;liver: 295.8 prostate: 16.3 -C18orf54 LAS2, MGC33382 ENSG00000166845 Chromosome 18 open reading frame 54 18 54357917-54385218 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA040704, HPA041098 Supported Nucleoplasm Tissue enriched 8 testis: 30.2 placenta: 3.7 -DCTN5 MGC3248, p25 ENSG00000166847 Dynactin 5 (p25) 16 23641392-23677455 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042003, HPA063710 Approved Supported Nucleoplasm
Nuclear membrane Expressed in all cerebral cortex: 38.2 -TERF2IP RAP1 ENSG00000166848 Telomeric repeat binding factor 2, interacting protein 16 75647786-75761872 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006719, CAB018660, CAB018749 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all cerebral cortex: 221.9 -PLK1 PLK ENSG00000166851 Polo-like kinase 1 16 23677656-23690367 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051638, HPA053229 Approved Tissue enhanced 0 testis: 44.0 lymph node: 33.2 -CLPX ENSG00000166855 Caseinolytic mitochondrial matrix peptidase chaperone subunit 15 65148219-65185342 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040262, HPA048199 Approved Validated Mitochondria Expressed in all skin: 17.7 -GPR182 ADMR, AM-R, G10D, hrhAMR ENSG00000166856 G protein-coupled receptor 182 12 56994446-56998441 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA027037 Supported Tissue enhanced 0 spleen: 12.4;testis: 6.6 liver: 2.0 -ZBTB39 KIAA0352, ZNF922 ENSG00000166860 Zinc finger and BTB domain containing 39 12 56998834-57006446 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA016866, HPA020306 Uncertain Approved Vesicles Mixed testis: 13.4 -CACNG2 MGC138502, MGC138504, stargazin ENSG00000166862 Calcium channel, voltage-dependent, gamma subunit 2 22 36563921-36703558 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 13 cerebral cortex: 15.4 adrenal gland: 1.2 -TAC3 NKB, NKNB, ZNEUROK1 ENSG00000166863 Tachykinin 3 12 57010000-57028883 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045919 Supported Tissue enriched 22 placenta: 610.5 cerebral cortex: 27.3 -MYO1A DFNA48, MYHL ENSG00000166866 Myosin IA 12 57028517-57051198 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053490 Supported Tissue enhanced 0 duodenum: 342.4;small intestine: 345.5 rectum: 73.2 -CHP2 ENSG00000166869 Calcineurin-like EF-hand protein 2 16 23754627-23758951 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB072806 Approved Group enriched 10 colon: 121.4;duodenum: 259.0;rectum: 130.7;skin: 144.2;small intestine: 232.0 cervix: 17.4 -NEMP1 KIAA0286, TMEM194, TMEM194A ENSG00000166881 Nuclear envelope integral membrane protein 1 12 57055643-57088063 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014394 Uncertain Approved Nucleoplasm Mixed lymph node: 14.6 -OR4D6 ENSG00000166884 Olfactory receptor, family 4, subfamily D, member 6 11 59456938-59457991 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.2 -NAB2 MADER ENSG00000166886 NGFI-A binding protein 2 (EGR1 binding protein 2) 12 57088894-57095476 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004510, HPA027464 Approved Approved Nucleus
Cytosol Expressed in all ovary: 39.3 -VPS39 KIAA0770, VAM6 ENSG00000166887 Vacuolar protein sorting 39 homolog (S. cerevisiae) 15 42158701-42208316 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 64.4 -STAT6 D12S1644, IL-4-STAT ENSG00000166888 Signal transducer and activator of transcription 6, interleukin-4 induced 12 57095408-57132139 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001861 Approved Validated Nucleoplasm
Cytosol Expressed in all skin: 164.0 -PATL1 FLJ36874, Pat1b ENSG00000166889 Protein associated with topoisomerase II homolog 1 (yeast) 11 59636716-59668980 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039030 Uncertain Supported Cytoplasmic bodies Expressed in all bone marrow: 37.0 -XRCC6BP1 KUB3 ENSG00000166896 XRCC6 binding protein 1 12 57941541-57957269 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035804, HPA043204 Uncertain Validated Vesicles
Plasma membrane
Cell Junctions
Cytosol Tissue enhanced 0 testis: 26.6 rectum: 5.6 -ELFN2 dJ63G5.3, KIAA1904, LRRC62, PPP1R29 ENSG00000166897 Extracellular leucine-rich repeat and fibronectin type III domain containing 2 22 37367960-37427470 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000781 Approved Approved Nucleoplasm
Vesicles Tissue enriched 7 cerebral cortex: 24.3 testis: 3.7 -STX3 STX3A ENSG00000166900 Syntaxin 3 11 59713456-59805882 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002191, HPA069176 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all placenta: 71.8 -MRPL16 FLJ20484, PNAS-111 ENSG00000166902 Mitochondrial ribosomal protein L16 11 59806135-59810872 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054133 Supported Expressed in all parathyroid gland: 70.2 -PIP4K2C FLJ22055, PIP5K2C ENSG00000166908 Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 12 57591174-57603418 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028658, HPA058551 Approved Approved Vesicles Expressed in all epididymis: 107.2 -MTMR10 FLJ20313 ENSG00000166912 Myotubularin related protein 10 15 30938941-30991607 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006081 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all placenta: 35.5 -YWHAB YWHAA ENSG00000166913 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 20 44885676-44908532 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003759, HPA007925, HPA011212 Supported Supported Cytosol Expressed in all cerebral cortex: 446.4 -C15orf48 NMES1 ENSG00000166920 Chromosome 15 open reading frame 48 15 45430529-45448761 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012677, HPA012943 Approved Uncertain Mitochondria Tissue enhanced 0 colon: 728.9;rectum: 845.4 small intestine: 336.3 -SCG5 7B2, SGNE1, SgV ENSG00000166922 Secretogranin V 15 32641676-32697098 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013136 Supported Tissue enhanced 0 cerebral cortex: 234.3;parathyroid gland: 189.3 adrenal gland: 80.7 -GREM1 CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS ENSG00000166923 Gremlin 1, DAN family BMP antagonist 15 32717974-32745107 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007526 Uncertain Tissue enhanced 0 gallbladder: 92.7;smooth muscle: 66.3 urinary bladder: 23.3 -NYAP1 C7orf51, FLJ37538, KIAA1486L ENSG00000166924 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 7 100483927-100494799 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA022251 Uncertain Supported Golgi apparatus
Vesicles Tissue enhanced 0 cerebral cortex: 25.2;testis: 7.7 adrenal gland: 3.3 -TSC22D4 THG-1, TILZ2 ENSG00000166925 TSC22 domain family, member 4 7 100463359-100479279 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006757 Uncertain Approved Cytosol Expressed in all cerebral cortex: 278.9 -MS4A6E ENSG00000166926 Membrane-spanning 4-domains, subfamily A, member 6E 11 60334831-60396596 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA076623 Approved Vesicles Tissue enriched 36 testis: 61.4 appendix: 1.6 -MS4A7 CD20L4, CFFM4, MS4A8 ENSG00000166927 Membrane-spanning 4-domains, subfamily A, member 7 11 60378482-60395951 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA017418, CAB026387 Approved Tissue enhanced 0 spleen: 321.1 lung: 125.3 -MS4A14 DKFZp434H092, FLJ32856, MS4A16, NYD-SP21 ENSG00000166928 Membrane-spanning 4-domains, subfamily A, member 14 11 60378530-60417756 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12 testis: 91.2 spleen: 7.7 -MS4A5 CD20L2 ENSG00000166930 Membrane-spanning 4-domains, subfamily A, member 5 11 60429589-60455214 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043732 Uncertain Tissue enriched 270 testis: 72.6 duodenum: 0.2 -DIS3L DIS3L1, FLJ38088, KIAA1955, MGC4562 ENSG00000166938 DIS3 like exosome 3'-5' exoribonuclease 15 66293217-66333898 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041805 Approved Approved Plasma membrane
Centrosome
Cytosol Expressed in all parathyroid gland: 26.1 -CCNDBP1 DIP1, GCIP ENSG00000166946 Cyclin D-type binding-protein 1 15 43185118-43197176 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020664, HPA041065 Supported Validated Nucleoplasm Mixed bone marrow: 7.6 -EPB42 MGC116735, MGC116737, PA ENSG00000166947 Erythrocyte membrane protein band 4.2 15 43106225-43221283 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040261 Supported Tissue enriched 13 bone marrow: 57.7 placenta: 4.4 -TGM6 dJ734P14.3, SCA35, TGM3L, TGY ENSG00000166948 Transglutaminase 6 20 2380908-2432753 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA059196 Uncertain Not detected tonsil: 0.4 -SMAD3 HsT17436, JV15-2, MADH3 ENSG00000166949 SMAD family member 3 15 67063763-67195195 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008094, HPA046386, HPA067203, CAB069409 Approved Validated Nucleoplasm
Cytosol Expressed in all esophagus: 54.4 -MS4A8 CD20L5, MS4A4, MS4A8B ENSG00000166959 Membrane-spanning 4-domains, subfamily A, member 8 11 60699574-60715811 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA007318, HPA007319 Supported Tissue enhanced 0 duodenum: 191.8;fallopian tube: 223.5;small intestine: 215.2 stomach: 49.6 -CCDC178 C18orf34, FLJ44050 ENSG00000166960 Coiled-coil domain containing 178 18 32937402-33441101 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA053265 Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 30.7 spleen: 10.8 -MS4A15 ENSG00000166961 Membrane-spanning 4-domains, subfamily A, member 15 11 60756953-60776732 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 11 lung: 71.5 endometrium: 6.2 -MAP1A MAP1L ENSG00000166963 Microtubule-associated protein 1A 15 43510958-43531620 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039063, HPA039064, HPA066488 Supported Approved Cytosol Tissue enriched 9 cerebral cortex: 166.1 smooth muscle: 18.7 -RCCD1 MGC14386 ENSG00000166965 RCC1 domain containing 1 15 90954870-90963125 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039683, HPA040776 Approved Validated Plasma membrane
Cytosol Mixed parathyroid gland: 8.8 -AKTIP FLJ13258, FTS ENSG00000166971 AKT interacting protein 16 53491040-53504411 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041794, HPA046300 Approved Expressed in all testis: 81.0 -MAPRE2 EB1, EB2, RP1 ENSG00000166974 Microtubule-associated protein, RP/EB family, member 2 18 34976928-35143470 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016738, HPA016739 Supported Uncertain Nucleoplasm Expressed in all cerebral cortex: 175.1 -EVA1C B18, B19, C21orf63, C21orf64, FAM176C, PRED34 ENSG00000166979 Eva-1 homolog C (C. elegans) 21 32412006-32515397 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015720, HPA029944, CAB034174 Approved Mixed fallopian tube: 24.9 -TCP10L2 bA517H2.3 ENSG00000166984 T-complex 10-like 2 6 167146414-167196913 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence CAB034197, HPA044709 Uncertain Tissue enhanced 0 epididymis: 1.5;testis: 1.5 small intestine: 0.3 -MARS CMT2U, MetRS, SPG70 ENSG00000166986 Methionyl-tRNA synthetase 12 57475445-57517569 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004125, CAB017097 Supported Approved Validated Cytosol Expressed in all testis: 66.4 -MBD6 KIAA1887 ENSG00000166987 Methyl-CpG binding domain protein 6 12 57520710-57530148 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038948, HPA038949 Uncertain Validated Nucleus Expressed in all testis: 66.5 -CNPY4 MGC40499, PRAT4B ENSG00000166997 Canopy FGF signaling regulator 4 7 100119613-100125511 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014166, HPA025240 Uncertain Approved Vesicles Mixed endometrium: 34.7 -PDIA3 ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC ENSG00000167004 Protein disulfide isomerase family A, member 3 15 43746392-43773279 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002645, HPA003230, CAB011199, CAB015181 Supported Validated Endoplasmic reticulum Expressed in all thyroid gland: 91.1 -NUDT21 CFIM25, CPSF5 ENSG00000167005 Nudix (nucleoside diphosphate linked moiety X)-type motif 21 16 56429133-56452199 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019863, HPA074228 Uncertain Supported Nuclear bodies
Microtubule organizing center Expressed in all testis: 128.2 -NAT16 C7orf52, FLJ39237 ENSG00000167011 N-acetyltransferase 16 (GCN5-related, putative) 7 101170493-101180276 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA021918 Uncertain Uncertain Nucleus Group enriched 8 cerebral cortex: 5.1;thyroid gland: 3.0 pancreas: 0.5 -C15orf43 MGC33951 ENSG00000167014 Chromosome 15 open reading frame 43 15 44956702-44979229 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041780, HPA041941 Uncertain Nucleus
Nucleoli
Centrosome Tissue enriched 22 testis: 39.9 breast: 1.7 -NKX3-1 BAPX2, NKX3.1, NKX3A ENSG00000167034 NK3 homeobox 1 8 23678693-23682927 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 12 prostate: 517.0 testis: 44.8 -SGSM1 KIAA1941, RUTBC2 ENSG00000167037 Small G protein signaling modulator 1 22 24806169-24927578 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003986 Approved Tissue enhanced 0 cerebral cortex: 14.8;parathyroid gland: 18.7 heart muscle: 9.8 -DUSP18 DUSP20 ENSG00000167065 Dual specificity phosphatase 18 22 30652051-30667890 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB034070, HPA051349 Approved Supported Nucleoplasm Mixed testis: 22.3 -TEF KIAA1655 ENSG00000167074 Thyrotrophic embryonic factor 22 41367333-41399326 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed cerebral cortex: 57.7 -MEI1 MGC40042, SPATA38 ENSG00000167077 Meiotic double-stranded break formation protein 1 22 41699499-41799456 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049240 Approved Uncertain Nucleoplasm
Plasma membrane Mixed testis: 18.7 -B4GALNT2 Cad, GALGT2, Sda ENSG00000167080 Beta-1,4-N-acetyl-galactosaminyl transferase 2 17 49132460-49176840 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015721 Approved Tissue enhanced 0 colon: 33.9 rectum: 16.1 -PBX3 ENSG00000167081 Pre-B-cell leukemia homeobox 3 9 125747345-125967377 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003881 Supported Approved Nucleoplasm Expressed in all parathyroid gland: 334.1 -GNGT2 GNG9 ENSG00000167083 Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 17 49202791-49210574 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043381 Supported Mixed spleen: 26.7 -PHB PHB1 ENSG00000167085 Prohibitin 17 49404049-49414905 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003280 Supported Supported Vesicles
Mitochondria Expressed in all kidney: 201.1 -SNRPD1 HsT2456, Sm-D1, SNRPD ENSG00000167088 Small nuclear ribonucleoprotein D1 polypeptide 16kDa 18 21612267-21633524 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040516 Supported Expressed in all lymph node: 82.3 -TTC16 FLJ32780 ENSG00000167094 Tetratricopeptide repeat domain 16 9 127716066-127731600 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 12 fallopian tube: 10.8;testis: 18.3 lung: 1.1 -SUN5 dJ726C3.1, SPAG4L, TSARG4 ENSG00000167098 Sad1 and UNC84 domain containing 5 20 32983773-33004433 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048529 Supported Tissue enriched 409 testis: 40.8 epididymis: 0.0 -SAMD14 FLJ36890 ENSG00000167100 Sterile alpha motif domain containing 14 17 50110040-50129882 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051916 Uncertain Approved Nucleus
Nucleoli fibrillar center Tissue enhanced 0 cerebral cortex: 6.3 testis: 1.8 -PIP5KL1 bA203J24.5, MGC46424 ENSG00000167103 Phosphatidylinositol-4-phosphate 5-kinase-like 1 9 127920879-127930797 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA056240 Uncertain Supported Cytosol Tissue enhanced 0 parathyroid gland: 3.7 skin: 2.2 -BPIFB6 BPIL3, LPLUNC6 ENSG00000167104 BPI fold containing family B, member 6 20 33031648-33044047 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043057 Uncertain Not detected epididymis: 0.0 -TMEM92 FLJ33318 ENSG00000167105 Transmembrane protein 92 17 50271406-50281485 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA063009, HPA069820 Approved Supported Nucleoplasm Tissue enhanced 0 duodenum: 41.4;small intestine: 51.6 gallbladder: 21.9 -FAM102A bA203J24.7, C9orf132, Eeig1, SYM-3A ENSG00000167106 Family with sequence similarity 102, member A 9 127940579-127980513 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036030 Approved Cytosol Mixed stomach: 101.5 -ACSF2 ACSMW, FLJ20920 ENSG00000167107 Acyl-CoA synthetase family member 2 17 50426158-50474845 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024693 Approved Approved Nucleoplasm
Microtubules
Cytosol Tissue enhanced 0 kidney: 136.1 thyroid gland: 68.3 -GOLGA2 GM130, golgin-95 ENSG00000167110 Golgin A2 9 128255829-128275995 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015421, HPA021178, HPA021230, HPA021799 Supported Validated Golgi apparatus Expressed in all parathyroid gland: 158.4 -TRUB2 CLONE24922 ENSG00000167112 TruB pseudouridine (psi) synthase family member 2 9 128305161-128322742 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021211, HPA052190 Uncertain Supported Cytosol Mixed cerebral cortex: 9.1 -COQ4 CGI-92 ENSG00000167113 Coenzyme Q4 9 128322536-128334072 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021406, HPA042945 Supported Supported Mitochondria Expressed in all fallopian tube: 64.1 -SLC27A4 ACSVL4, FATP4 ENSG00000167114 Solute carrier family 27 (fatty acid transporter), member 4 9 128340646-128361470 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007293, CAB009771 Approved Supported Vesicles Expressed in all duodenum: 74.1 -URM1 C9orf74, MGC2668 ENSG00000167118 Ubiquitin related modifier 1 9 128371319-128392016 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053645, HPA065160 Approved Approved Nucleoplasm
Vesicles Expressed in all fallopian tube: 24.9 -CERCAM CEECAM1, CerCAM, GLT25D3 ENSG00000167123 Cerebral endothelial cell adhesion molecule 9 128411751-128437351 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021657, HPA051595 Uncertain Approved Nucleus
Nucleoli
Cell Junctions Expressed in all cerebral cortex: 156.0 -DOLPP1 LSFR2 ENSG00000167130 Dolichyldiphosphatase 1 9 129081100-129090438 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA019179 Approved Approved Vesicles
Intermediate filaments Expressed in all duodenum: 26.5 -CCDC103 CILD17, FLJ13094, FLJ34211, PR46b ENSG00000167131 Coiled-coil domain containing 103 17 44899142-44905390 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043131 Approved Cytosol Group enriched 6 fallopian tube: 24.2;testis: 27.4 cerebral cortex: 4.4 -ENDOG ENSG00000167136 Endonuclease G 9 128818474-128822677 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021335, HPA021830 Approved Expressed in all skeletal muscle: 45.8 -TBC1D21 MGC34741, MgcRabGAP ENSG00000167139 TBC1 domain family, member 21 15 73873608-73889214 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043319 Uncertain Supported Tissue enriched 600 testis: 61.6 small intestine: 0.1 -PRRX2 PMX2, PRX2 ENSG00000167157 Paired related homeobox 2 9 129665641-129722674 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA006607, HPA026808 Approved Approved Nucleoplasm
Nuclear bodies Tissue enhanced 0 cervix, uterine: 9.8;skin: 10.7 testis: 6.3 -UGT1A6 GNT1, HLUGP, UGT1F ENSG00000167165 UDP glucuronosyltransferase 1 family, polypeptide A6 2 233691607-233773300 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009819, HPA054065 Supported Group enriched 6 kidney: 74.7;liver: 71.9;urinary bladder: 112.0 esophagus: 15.2 -C15orf39 DKFZP434H132, FLJ46337 ENSG00000167173 Chromosome 15 open reading frame 39 15 75195643-75212169 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039961, HPA041907 Uncertain Validated Cytosol Tissue enhanced 0 testis: 123.9 bone marrow: 39.1 -ISLR2 KIAA1465 ENSG00000167178 Immunoglobulin superfamily containing leucine-rich repeat 2 15 74100311-74138540 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012930, HPA067333 Uncertain Group enriched 5 cerebral cortex: 31.2;testis: 15.2 endometrium: 4.5 -SP2 KIAA0048 ENSG00000167182 Sp2 transcription factor 17 47896150-47928957 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003357, CAB010245 Supported Validated Nucleoplasm
Vesicles Expressed in all parathyroid gland: 31.3 -PRR15L ATAD4, MGC11242 ENSG00000167183 Proline rich 15-like 17 47951967-47957878 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA022918 Approved Approved Cytosol Tissue enhanced 0 duodenum: 185.5 small intestine: 144.4 -COQ7 CAT5, CLK-1 ENSG00000167186 Coenzyme Q7 homolog, ubiquinone (yeast) 16 19067599-19080095 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067252, HPA071922 Approved Approved Nucleoplasm
Plasma membrane Expressed in all parathyroid gland: 38.6 -GPRC5B RAIG-2 ENSG00000167191 G protein-coupled receptor, class C, group 5, member B 16 19856691-19886167 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA015247 Approved Supported Nucleus
Nucleoli
Vesicles Tissue enhanced 0 cerebral cortex: 309.2 testis: 66.5 -CRK ENSG00000167193 V-crk avian sarcoma virus CT10 oncogene homolog 17 1420689-1463162 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010485, HPA068087 Approved Approved Plasma membrane Expressed in all thyroid gland: 60.9 -C16orf92 FLJ25404 ENSG00000167194 Chromosome 16 open reading frame 92 16 30023334-30027736 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 7 testis: 24.0 cerebral cortex: 3.5 -GOLGA6C ENSG00000167195 Golgin A6 family, member C 15 75258599-75270199 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA044978, HPA050087 Supported Tissue enriched 56 testis: 9.3 skeletal muscle: 0.1 -FBXO22 FBX22, FISTC1 ENSG00000167196 F-box protein 22 15 75903859-75942510 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 15.2 -TBC1D2B KIAA1055 ENSG00000167202 TBC1 domain family, member 2B 15 77984036-78077724 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048174, HPA052663 Approved Approved Vesicles Expressed in all lung: 57.6 -NOD2 BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, PSORAS1 ENSG00000167207 Nucleotide-binding oligomerization domain containing 2 16 50693603-50733077 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041985, HPA054494 Approved Approved Golgi apparatus
Cytosol Mixed skin: 11.3 -SNX20 SLIC-1, SLIC1 ENSG00000167208 Sorting nexin 20 16 50666300-50681353 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043649 Uncertain Uncertain Nucleoplasm Tissue enhanced 0 appendix: 27.3;lymph node: 31.9 spleen: 26.3 -LOXHD1 DFNB77, FLJ32670, LH2D1 ENSG00000167210 Lipoxygenase homology domains 1 18 46476972-46657033 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 5 testis: 41.4 epididymis: 8.2 -KATNAL2 DKFZP667C165, MGC33211 ENSG00000167216 Katanin p60 subunit A-like 2 18 46917492-47102243 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040712, HPA042029 Approved Approved Nucleoplasm
Intermediate filaments Tissue enhanced 0 parathyroid gland: 45.5 testis: 33.0 -HDHD2 DKFZP564D1378 ENSG00000167220 Haloacid dehalogenase-like hydrolase domain containing 2 18 47107403-47150520 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040697, CAB045978, HPA059818 Approved Approved Vesicles Expressed in all cerebral cortex: 49.0 -ZNF91 HPF7, HTF10 ENSG00000167232 Zinc finger protein 91 19 23304991-23395560 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed thyroid gland: 17.5 -IGF2 C11orf43, FLJ44734, IGF-II ENSG00000167244 Insulin-like growth factor 2 11 2129112-2141238 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007556, HPA007993 Supported Approved Nucleoplasm
Vesicles Tissue enriched 18 placenta: 3974.6 fallopian tube: 220.1 -RNF214 DKFZp547C195 ENSG00000167257 Ring finger protein 214 11 117232625-117286445 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039332 Approved Approved Golgi apparatus
Cytosol Expressed in all testis: 33.1 -CDK12 CRK7, CRKR, CRKRS, KIAA0904 ENSG00000167258 Cyclin-dependent kinase 12 17 39461511-39564907 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008038 Supported Supported Nucleus Expressed in all testis: 33.8 -DPEP2 ENSG00000167261 Dipeptidase 2 16 67987394-68000586 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035644 Approved Tissue enhanced 0 spleen: 39.4 lung: 28.2 -DUS2 DUS2L, FLJ20399, SMM1 ENSG00000167264 Dihydrouridine synthase 2 16 67987746-68079320 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042560, HPA043528 Approved Validated Cytosol Mixed testis: 39.2 -POP5 ENSG00000167272 POP5 homolog, ribonuclease P/MRP subunit 12 120578764-120581398 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047598, HPA069204 Approved Approved Nucleus
Nucleoli Expressed in all parathyroid gland: 50.8 -ENGASE FLJ21865 ENSG00000167280 Endo-beta-N-acetylglucosaminidase 17 79074939-79088599 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021551 Approved Approved Centrosome
Cytosol Expressed in all spleen: 28.6 -RBFOX3 FOX-3, HRNBP3, NeuN ENSG00000167281 RNA binding protein, fox-1 homolog (C. elegans) 3 17 79089345-79516148 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030790 Supported Supported Nucleoplasm Tissue enhanced 0 cerebral cortex: 62.5;seminal vesicle: 33.0 prostate: 21.5 -ATP5L ATP5JG ENSG00000167283 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 11 118401154-118431496 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044629 Approved Supported Mitochondria Expressed in all kidney: 116.1 -CD3D T3D ENSG00000167286 CD3d molecule, delta (CD3-TCR complex) 11 118338954-118342744 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013055 Supported Tissue enhanced 0 lymph node: 202.6;tonsil: 124.1 appendix: 90.4 -TBC1D16 FLJ20748, MGC25062 ENSG00000167291 TBC1 domain family, member 16 17 79932343-80035848 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024482, HPA065839 Approved Approved Intermediate filaments Mixed adipose tissue: 40.6 -ENTHD2 C17orf56, FLJ31528 ENSG00000167302 ENTH domain containing 2 17 81228277-81239091 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063410 Supported Nuclear membrane
Nuclear speckles
Golgi apparatus Expressed in all spleen: 15.1 -MYO5B KIAA1119 ENSG00000167306 Myosin VB 18 49822813-50195093 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040593, HPA040902, HPA069773 Supported Approved Plasma membrane Mixed small intestine: 69.4 -ART5 ENSG00000167311 ADP-ribosyltransferase 5 11 3638503-3642316 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041637, HPA044099 Uncertain Tissue enhanced 0 ovary: 10.2;testis: 22.6 endometrium: 5.1 -ACAA2 DSAEC ENSG00000167315 Acetyl-CoA acyltransferase 2 18 49782167-49813960 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042303 Supported Supported Mitochondria Expressed in all liver: 508.4 -STIM1 D11S4896E, GOK ENSG00000167323 Stromal interaction molecule 1 11 3854527-4093210 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011088, HPA012123, CAB037128, CAB037288 Supported Validated Endoplasmic reticulum Expressed in all parathyroid gland: 86.3 -RRM1 ENSG00000167325 Ribonucleotide reductase M1 11 4094707-4138876 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022093, HPA057265, HPA064297 Supported Validated Cytosol Expressed in all parathyroid gland: 59.5 -OR51E2 PSGR ENSG00000167332 Olfactory receptor, family 51, subfamily E, member 2 11 4680171-4697854 Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 7 prostate: 38.9 placenta: 5.8 -TRIM68 FLJ10369, RNF137, SS-56 ENSG00000167333 Tripartite motif containing 68 11 4598672-4608259 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023455 Uncertain Supported Nucleus
Cytosol Expressed in all thyroid gland: 16.0 -MMP26 endometase, MGC126590, MGC126592 ENSG00000167346 Matrix metallopeptidase 26 11 4704927-4992429 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 64 endometrium: 23.8 prostate: 0.3 -OR51I1 ENSG00000167359 Olfactory receptor, family 51, subfamily I, member 1 11 5440570-5441514 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.1 -OR51Q1 ENSG00000167360 Olfactory receptor, family 51, subfamily Q, member 1 (gene/pseudogene) 11 5422111-5423206 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044998 Uncertain Not detected epididymis: 0.1 -FN3K ENSG00000167363 Fructosamine 3 kinase 17 82735575-82751197 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059151, HPA061358 Supported Approved Mitochondria Expressed in all cerebral cortex: 57.1 -PRRT2 DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC ENSG00000167371 Proline-rich transmembrane protein 2 16 29811382-29815892 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014447, HPA019203 Approved Supported Plasma membrane Tissue enhanced 0 cerebral cortex: 92.9 ovary: 51.5 -ZNF23 KOX16, Zfp612, ZNF359, ZNF612 ENSG00000167377 Zinc finger protein 23 16 71447597-71463095 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023534 Uncertain Approved Cytosol Mixed cerebral cortex: 12.2 -IRGQ FKSG27, IRGQ1 ENSG00000167378 Immunity-related GTPase family, Q 19 43584369-43596135 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043254, HPA050338 Approved Supported Vesicles Mixed cerebral cortex: 7.3 -ZNF226 ENSG00000167380 Zinc finger protein 226 19 44165073-44178381 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA006145, CAB034353 Uncertain Approved Nuclear bodies Expressed in all thyroid gland: 39.7 -ZNF180 HHZ168 ENSG00000167384 Zinc finger protein 180 19 44474428-44500524 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA028979, HPA028980 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 11.9 -PPP2R3B PPP2R3L, PPP2R3LY, PR48 ENSG00000167393 Protein phosphatase 2, regulatory subunit B'', beta X 333963-386955 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA074545 Uncertain Endoplasmic reticulum Tissue enhanced 0 skeletal muscle: 14.7 heart muscle: 6.7 -ZNF668 FLJ13479 ENSG00000167394 Zinc finger protein 668 16 31060843-31074320 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043048 Uncertain Approved Nucleus
Nucleoli Mixed testis: 8.0 -ZNF646 KIAA0296 ENSG00000167395 Zinc finger protein 646 16 31074422-31084196 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042364 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 testis: 34.4 spleen: 11.0 -VKORC1 VKCFD2 ENSG00000167397 Vitamin K epoxide reductase complex, subunit 1 16 31090842-31095980 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042720 Approved Expressed in all liver: 141.1 -GNG8 ENSG00000167414 Guanine nucleotide binding protein (G protein), gamma 8 19 46634076-46634685 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adrenal gland: 29.5 cerebral cortex: 10.3 -LPO SPO ENSG00000167419 Lactoperoxidase 17 58218548-58268518 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028688 Supported Tissue enriched 219 salivary gland: 374.4 testis: 1.7 -CA4 CAIV, Car4, RP17 ENSG00000167434 Carbonic anhydrase IV 17 60149936-60170899 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011089, HPA017258 Approved Supported Vesicles Tissue enhanced 0 colon: 258.2;rectum: 183.7 adipose tissue: 88.6 -SMG8 C17orf71, FLJ10587, FLJ23205 ENSG00000167447 SMG8 nonsense mediated mRNA decay factor 17 59209400-59215247 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024841 Approved Approved Nucleoplasm Expressed in all testis: 13.9 -TPM4 ENSG00000167460 Tropomyosin 4 19 16067021-16103005 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004685, HPA047089, HPA053624 Approved Approved Actin filaments
Cytosol Expressed in all smooth muscle: 808.6 -RAB8A MEL, RAB8 ENSG00000167461 RAB8A, member RAS oncogene family 19 16111629-16134234 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041945 Supported Nucleus
Plasma membrane Expressed in all small intestine: 65.9 -GPX4 MCSP, PHGPx ENSG00000167468 Glutathione peroxidase 4 19 1103926-1106791 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008630, HPA047224, HPA058546 Supported Supported Nucleoplasm
Mitochondria Expressed in all testis: 1137.7 -MIDN ENSG00000167470 Midnolin 19 1248553-1259140 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042018, HPA049432 Uncertain Approved Nucleoplasm Expressed in all bone marrow: 51.6 -JSRP1 FLJ32416, JP-45 ENSG00000167476 Junctional sarcoplasmic reticulum protein 1 19 2252252-2269759 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044741 Supported Approved Endoplasmic reticulum Tissue enriched 27 skeletal muscle: 120.0 duodenum: 4.5 -FAM129C BCNP1, FLJ39802 ENSG00000167483 Family with sequence similarity 129, member C 19 17523301-17553839 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043277 Approved Group enriched 15 appendix: 14.5;bone marrow: 11.3;lymph node: 28.5;spleen: 37.6;tonsil: 9.7 gallbladder: 1.3 -KLHL26 ENSG00000167487 Kelch-like family member 26 19 18636965-18671714 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023074 Uncertain Mixed cerebral cortex: 11.2 -GATAD2A p66alpha ENSG00000167491 GATA zinc finger domain containing 2A 19 19385826-19508931 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006759, HPA024373 Supported Validated Nucleoplasm Expressed in all testis: 64.2 -MVD MPD ENSG00000167508 Mevalonate (diphospho) decarboxylase 16 88651935-88663161 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041404, HPA048250 Uncertain Approved Cell Junctions
Cytosol Expressed in all duodenum: 34.8 -CDT1 DUP, RIS2 ENSG00000167513 Chromatin licensing and DNA replication factor 1 16 88803213-88809258 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017224 Approved Supported Nucleus
Nuclear bodies Tissue enhanced 0 bone marrow: 20.4 lymph node: 4.7 -TRAPPC2L HSPC176 ENSG00000167515 Trafficking protein particle complex 2-like 16 88856220-88862686 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041714 Approved Supported Vesicles
Cytosol Expressed in all adrenal gland: 91.9 -ANKRD11 LZ16, T13 ENSG00000167522 Ankyrin repeat domain 11 16 89267627-89490561 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019288, HPA041593, HPA049470 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 24.4 -SPATA33 C16orf55, FLJ31606 ENSG00000167523 Spermatogenesis associated 33 16 89657802-89671272 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045648, HPA073096 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 testis: 77.1 fallopian tube: 25.5 -SGK494 ENSG00000167524 Uncharacterized serine/threonine-protein kinase SgK494 17 28607964-28614200 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA046590 Uncertain Approved Nucleoplasm
Vesicles
Plasma membrane Mixed testis: 11.4 -PROCA1 MGC39650 ENSG00000167525 Protein interacting with cyclin A1 17 28703197-28711854 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023648 Approved Tissue enriched 20 testis: 139.6 spleen: 7.0 -RPL13 BBC1, D16S444E, L13 ENSG00000167526 Ribosomal protein L13 16 89560657-89566828 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051702 Approved Validated Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 3867.8 -ZNF641 FLJ31295 ENSG00000167528 Zinc finger protein 641 12 48337180-48351414 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA035189 Uncertain Supported Nucleoplasm Expressed in all adrenal gland: 29.0 -LALBA LYZL7 ENSG00000167531 Lactalbumin, alpha- 12 48567684-48570066 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB026343, HPA029855, HPA029856 Supported Tissue enriched 572 breast: 2487.9 testis: 4.3 -CACNB3 CACNLB3 ENSG00000167535 Calcium channel, voltage-dependent, beta 3 subunit 12 48813794-48828941 FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059515 Approved Golgi apparatus
Vesicles Mixed endometrium: 39.8 -DHRS13 MGC23280, SDR7C5 ENSG00000167536 Dehydrogenase/reductase (SDR family) member 13 17 28897781-28903071 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA022991 Uncertain Approved Vesicles Mixed bone marrow: 25.2 -TP53I13 DSCP1 ENSG00000167543 Tumor protein p53 inducible protein 13 17 29566052-29573157 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all spleen: 54.3 -KMT2D ALR, CAGL114, MLL2, MLL4, TNRC21 ENSG00000167548 Lysine (K)-specific methyltransferase 2D 12 49018975-49059774 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035977 Approved Approved Nucleus
Plasma membrane
Cytosol Expressed in all parathyroid gland: 45.7 -CORO6 FLJ14871 ENSG00000167549 Coronin 6 17 29614756-29622907 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021556 Supported Golgi apparatus Tissue enhanced 0 skeletal muscle: 127.6 heart muscle: 47.1 -RHEBL1 FLJ25797, MGC34869 ENSG00000167550 Ras homolog enriched in brain like 1 12 49064685-49070025 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053111, HPA061001 Uncertain Uncertain Nucleus
Centrosome Mixed fallopian tube: 4.1 -TUBA1A B-ALPHA-1, FLJ25113, TUBA3 ENSG00000167552 Tubulin, alpha 1a 12 49184796-49189324 Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB008686, HPA039247, HPA043684, HPA063394 Supported Validated Microtubules Expressed in all cerebral cortex: 1377.5 -TUBA1C bcm948, MGC10851, MGC14580, TUBA6 ENSG00000167553 Tubulin, alpha 1c 12 49188736-49274603 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039247, HPA043684, HPA063394 Supported Supported Microtubules Expressed in all esophagus: 312.5 -ZNF610 FLJ36040 ENSG00000167554 Zinc finger protein 610 19 52336245-52367778 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055771 Approved Tissue enhanced 0 testis: 22.1 ovary: 10.4 -ZNF528 KIAA1827 ENSG00000167555 Zinc finger protein 528 19 52397849-52418412 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA065435 Approved Nuclear speckles
Cytosol Expressed in all thyroid gland: 31.1 -ZNF701 FLJ10891 ENSG00000167562 Zinc finger protein 701 19 52555822-52587174 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA005532 Uncertain Approved Nucleoplasm
Microtubule organizing center Mixed thyroid gland: 10.0 -SERTAD3 RBT1 ENSG00000167565 SERTA domain containing 3 19 40440844-40444705 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA068262 Supported Nucleoli Expressed in all prostate: 39.5 -NCKAP5L KIAA1602 ENSG00000167566 NCK-associated protein 5-like 12 49791146-49828750 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041034 Approved Approved Golgi apparatus Expressed in all placenta: 12.8 -RAB4B FLJ78649, MGC52123 ENSG00000167578 RAB4B, member RAS oncogene family 19 40778216-40796938 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 56.2 -AQP2 ENSG00000167580 Aquaporin 2 (collecting duct) 12 49950741-49958881 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA046834 Supported Group enriched 93 kidney: 432.9;seminal vesicle: 299.3 prostate: 3.9 -GPD1 ENSG00000167588 Glycerol-3-phosphate dehydrogenase 1 (soluble) 12 50103819-50111319 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044620 Supported Tissue enhanced 0 adipose tissue: 635.1;skeletal muscle: 195.8 kidney: 147.2 -PROSER3 C19orf55, FLJ30657 ENSG00000167595 Proline and serine rich 3 19 35758143-35771028 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058492 Approved Approved Golgi apparatus Mixed testis: 14.2 -CYP2S1 ENSG00000167600 Cytochrome P450, family 2, subfamily S, polypeptide 1 19 41193049-41207539 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049227 Approved Endoplasmic reticulum Tissue enhanced 0 duodenum: 99.4;small intestine: 70.0;stomach: 113.4 colon: 26.4 -AXL ARK, JTK11, Tyro7, UFO ENSG00000167601 AXL receptor tyrosine kinase 19 41219203-41261766 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032501, HPA037422, HPA037423 Uncertain Approved Intermediate filaments Expressed in all smooth muscle: 54.0 -NFKBID IkappaBNS, TA-NFKBH ENSG00000167604 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta 19 35887653-35902303 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043573 Approved Mitochondria Tissue enhanced 0 bone marrow: 9.8 appendix: 6.1 -TMC4 ENSG00000167608 Transmembrane channel-like 4 19 54160108-54173250 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048635 Approved Tissue enhanced 0 duodenum: 31.3 small intestine: 22.6 -ANKRD33 C12orf7, DKFZp686O1689, PANKY ENSG00000167612 Ankyrin repeat domain 33 12 51887960-51891664 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA040013, HPA058753 Uncertain Not detected placenta: 0.5 -LAIR1 CD305 ENSG00000167613 Leukocyte-associated immunoglobulin-like receptor 1 19 54351384-54370558 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011155 Supported Supported Plasma membrane Tissue enhanced 0 lymph node: 7.2 appendix: 4.3 -TTYH1 ENSG00000167614 Tweety family member 1 19 54415219-54436900 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023617, HPA050655 Approved Tissue enriched 27 cerebral cortex: 57.9 testis: 2.1 -LENG8 KIAA1932, MGC40108, pp13842 ENSG00000167615 Leukocyte receptor cluster (LRC) member 8 19 54448887-54462037 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042004, HPA042056, HPA061571 Uncertain Supported Nucleus Expressed in all spleen: 167.8 -CDC42EP5 Borg3, CEP5 ENSG00000167617 CDC42 effector protein (Rho GTPase binding) 5 19 54465026-54473264 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043449 Approved Tissue enhanced 0 colon: 3.2;prostate: 2.0 adipose tissue: 0.9 -LAIR2 CD306 ENSG00000167618 Leukocyte-associated immunoglobulin-like receptor 2 19 54497879-54510687 CD markers, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lymph node: 1.4 spleen: 0.8 -TMEM145 FLJ90805 ENSG00000167619 Transmembrane protein 145 19 42313325-42325062 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA060462 Supported Approved Vesicles Tissue enriched 6 cerebral cortex: 38.4 adrenal gland: 6.0 -ZNF526 KIAA1951, MGC4267 ENSG00000167625 Zinc finger protein 526 19 42220271-42228201 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023070, HPA056609 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Mixed skin: 6.2 -TRAPPC9 IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120 ENSG00000167632 Trafficking protein particle complex 9 8 139730343-140458579 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026579 Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all parathyroid gland: 48.7 -KIR3DL1 AMB11, CD158E1, CD158e1/2, CD158e2, cl-11, cl-2, KIR, nkat3, NKB1, NKB1B ENSG00000167633 Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 19 54816468-54866993 CD markers, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected bone marrow: 0.3 -NLRP7 CLR19.4, NALP7, NOD12, PAN7, PYPAF3 ENSG00000167634 NLR family, pyrin domain containing 7 19 54923509-54966312 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051382 Uncertain Uncertain Golgi apparatus Tissue enriched 13 testis: 2.8 duodenum: 0.2 -ZNF146 OZF ENSG00000167635 Zinc finger protein 146 19 36214602-36238774 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003358 Supported Supported Nucleoli Expressed in all parathyroid gland: 62.1 -ZNF283 ENSG00000167637 Zinc finger protein 283 19 43827292-43852017 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA072977 Approved Nucleoplasm Mixed parathyroid gland: 10.0 -PPP1R14A CPI-17, PPP1INL ENSG00000167641 Protein phosphatase 1, regulatory (inhibitor) subunit 14A 19 38251237-38256591 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005044, CAB009803, HPA042097, HPA054534 Supported Supported Nucleoplasm
Nuclear bodies Mixed seminal vesicle: 109.5 -SPINT2 HAI-2, Kop ENSG00000167642 Serine peptidase inhibitor, Kunitz type, 2 19 38244035-38292614 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011101, CAB018969 Approved Uncertain Plasma membrane
Intermediate filaments
Cytosol Mixed thyroid gland: 536.5 -C19orf33 H2RSP, IMUP, IMUP-1, IMUP-2 ENSG00000167644 Chromosome 19 open reading frame 33 19 38304161-38305009 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054406, HPA059696 Uncertain Supported Nucleus
Plasma membrane
Cytosol Mixed esophagus: 178.5 -YIF1B FinGER8 ENSG00000167645 Yip1 interacting factor homolog B (S. cerevisiae) 19 38305104-38317273 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039328, HPA055257, HPA062675 Approved Approved Golgi apparatus
Vesicles Expressed in all cerebral cortex: 49.6 -DNAAF3 C19orf51, CILD2, FLJ36139, FLJ40069, PCD, PF22 ENSG00000167646 Dynein, axonemal, assembly factor 3 19 55158661-55166722 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042118, HPA056220 Uncertain Approved Nuclear bodies
Mitochondria Group enriched 11 fallopian tube: 68.1;testis: 68.1 lung: 5.9 -PSCA ENSG00000167653 Prostate stem cell antigen 8 142670308-142682724 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030783, HPA056418 Approved Supported Plasma membrane Tissue enhanced 0 stomach: 1662.7;urinary bladder: 357.0 prostate: 312.0 -ATCAY BNIP-H ENSG00000167654 Ataxia, cerebellar, Cayman type 19 3879864-3928079 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017755 Supported Tissue enriched 12 cerebral cortex: 109.9 adrenal gland: 8.9 -LY6D E48 ENSG00000167656 Lymphocyte antigen 6 complex, locus D 8 142784880-142786592 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024755, HPA064317 Supported Group enriched 11 esophagus: 634.4;skin: 717.6 tonsil: 63.5 -DAPK3 ZIP, ZIPK ENSG00000167657 Death-associated protein kinase 3 19 3958453-3971123 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028569, HPA064809 Approved Approved Nucleus Expressed in all endometrium: 76.1 -EEF2 EEF-2, EF2 ENSG00000167658 Eukaryotic translation elongation factor 2 19 3976056-3985469 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007795, HPA040534, HPA057351 Approved Validated Plasma membrane
Cytosol Expressed in all ovary: 1621.9 -TMIGD2 CD28H, IGPR-1, MGC23244 ENSG00000167664 Transmembrane and immunoglobulin domain containing 2 19 4292232-4302431 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011081 Approved Tissue enhanced 0 lymph node: 7.5 appendix: 5.7 -CHAF1A CAF-1, CAF1, CAF1B, CAF1P150, MGC71229, P150 ENSG00000167670 Chromatin assembly factor 1, subunit A (p150) 19 4402662-4445018 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015186 Approved Supported Nucleus
Cytosol Mixed testis: 21.9 -UBXN6 UBXD1, UBXDC2 ENSG00000167671 UBX domain protein 6 19 4444999-4457822 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040906, HPA041313, HPA061872 Approved Approved Golgi apparatus
Cytosol Expressed in all testis: 139.2 -CTB-50L17.10 ENSG00000167674 Hepatoma-derived growth factor-related protein 2 19 4472287-4502211 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042559, HPA044208 Supported Supported Nucleoplasm Expressed in all testis: 62.3 -PLIN4 KIAA1881, S3-12 ENSG00000167676 Perilipin 4 19 4502180-4518465 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044682, HPA054657 Supported Supported Vesicles
Lipid droplets
Plasma membrane
Cytosol Tissue enriched 14 adipose tissue: 810.9 skeletal muscle: 59.1 -SEMA6B SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ ENSG00000167680 Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 19 4542593-4559808 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB025157, HPA055778, HPA058523 Approved Tissue enhanced 0 cerebral cortex: 65.7 spleen: 24.9 -ZNF444 EZF2, FLJ11137, ZSCAN17 ENSG00000167685 Zinc finger protein 444 19 56132599-56160893 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056895, HPA065203 Approved Supported Nucleus
Nucleoli Expressed in all seminal vesicle: 29.1 -NXN FLJ12614, NRX ENSG00000167693 Nucleoredoxin 17 799313-979770 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023566 Approved Supported Golgi apparatus
Cytosol Mixed endometrium: 42.6 -FAM57A CT120, FLJ22282 ENSG00000167695 Family with sequence similarity 57, member A 17 732412-742972 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skin: 82.8 esophagus: 26.0 -GLOD4 C17orf25, CGI-150, HC71 ENSG00000167699 Glyoxalase domain containing 4 17 757097-783390 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021623, HPA023246, HPA023248 Supported Approved Nucleus
Nucleoli
Cytosol Expressed in all duodenum: 83.4 -MFSD3 ENSG00000167700 Major facilitator superfamily domain containing 3 8 144509074-144511213 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056013 Uncertain Approved Vesicles Expressed in all parathyroid gland: 14.2 -GPT ALT1, GPT1 ENSG00000167701 Glutamic-pyruvate transaminase (alanine aminotransferase) 8 144502973-144507174 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031059, HPA031060, CAB032997, CAB032999 Supported Mixed liver: 25.0 -KIFC2 ENSG00000167702 Kinesin family member C2 8 144466043-144474202 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029264 Approved Supported Nucleoplasm
Cytosol Expressed in all skin: 73.3 -SLC43A2 MGC34680 ENSG00000167703 Solute carrier family 43 (amino acid system L transporter), member 2 17 1569267-1628886 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021564 Approved Tissue enhanced 0 placenta: 31.6 appendix: 17.4 -RILP FLJ31193 ENSG00000167705 Rab interacting lysosomal protein 17 1646145-1650077 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed skeletal muscle: 8.7 -SERPINF2 A2AP, AAP, ALPHA-2-PI, API, PLI ENSG00000167711 Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 17 1742836-1755268 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001885, CAB024863 Approved Uncertain Nucleoplasm
Vesicles Tissue enhanced 0 epididymis: 115.3;liver: 452.4 kidney: 63.1 -WDR81 FLJ33817, PPP1R166 ENSG00000167716 WD repeat domain 81 17 1716523-1738599 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023044 Uncertain Approved Nucleoplasm Mixed spleen: 10.6 -SRR ILV1, ISO1 ENSG00000167720 Serine racemase 17 2303383-2325260 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007529, CAB015343 Approved Approved Vesicles Expressed in all cerebral cortex: 25.6 -TSR1 FLJ10534 ENSG00000167721 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 17 2322503-2337507 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024434, HPA053087 Approved Supported Nucleoplasm Expressed in all testis: 28.7 -TRPV3 VRL3 ENSG00000167723 Transient receptor potential cation channel, subfamily V, member 3 17 3510502-3557995 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069550 Approved Plasma membrane
Centrosome
Cytosol Tissue enhanced 0 skin: 5.2;small intestine: 4.6 duodenum: 1.7 -HSD11B1L SCDR10, SDR26C2 ENSG00000167733 Hydroxysteroid (11-beta) dehydrogenase 1-like 19 5680604-5688523 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049078 Approved Vesicles Tissue enhanced 0 cerebral cortex: 25.7 fallopian tube: 8.0 -CYB5D2 MGC32124 ENSG00000167740 Cytochrome b5 domain containing 2 17 4143168-4187310 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042299 Approved Approved Nuclear membrane
Nucleoli
Centrosome Expressed in all parathyroid gland: 51.5 -GGT6 FLJ90165 ENSG00000167741 Gamma-glutamyltransferase 6 17 4556927-4560818 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023362, HPA027213 Approved Mixed colon: 55.8 -C19orf48 MGC13170 ENSG00000167747 Chromosome 19 open reading frame 48 19 50797704-50804929 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA042000 Uncertain Approved Plasma membrane Expressed in all prostate: 76.2 -KLK1 Klk6 ENSG00000167748 Kallikrein 1 19 50819148-50823787 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 35 pancreas: 1994.3;salivary gland: 2571.5 colon: 64.8 -KLK4 EMSP, EMSP1, KLK-L1, PRSS17, PSTS ENSG00000167749 Kallikrein-related peptidase 4 19 50906352-50910738 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051839 Supported Tissue enriched 36 prostate: 395.8 skin: 10.9 -KLK2 ENSG00000167751 Kallikrein-related peptidase 2 19 50861568-50880567 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000764 Supported Tissue enriched 174 prostate: 850.1 testis: 4.8 -KLK5 KLK-L2, SCTE ENSG00000167754 Kallikrein-related peptidase 5 19 50943303-50953093 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014343, CAB025503, CAB026341 Supported Tissue enriched 6 skin: 213.9 breast: 37.5 -KLK6 Bssp, Klk7, neurosin, PRSS18, PRSS9 ENSG00000167755 Kallikrein-related peptidase 6 19 50958631-50969673 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051837 Supported Nucleoplasm
Nuclear membrane
Cytokinetic bridge Group enriched 5 cerebral cortex: 79.0;esophagus: 63.2;fallopian tube: 44.3;tonsil: 32.5 kidney: 10.1 -KLK11 PRSS20, TLSP ENSG00000167757 Kallikrein-related peptidase 11 19 51022216-51028039 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB026340 Approved Tissue enhanced 0 esophagus: 226.6;skin: 214.5 prostate: 107.3 -KLK13 KLK-L4 ENSG00000167759 Kallikrein-related peptidase 13 19 51056206-51065114 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA062136 Supported Tissue enriched 9 esophagus: 403.9 tonsil: 46.8 -ZNF83 FLJ11015, HPF1, ZNF816B ENSG00000167766 Zinc finger protein 83 19 52594060-52690496 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA025970 Approved Approved Nucleoplasm Expressed in all epididymis: 110.8 -KRT80 KB20 ENSG00000167767 Keratin 80, type II 12 52168996-52192000 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA077836, HPA077918 Validated Intermediate filaments Tissue enhanced 0 skin: 125.3 tonsil: 39.1 -KRT1 EHK1, KRT1A ENSG00000167768 Keratin 1, type II 12 52674736-52680407 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002153, HPA017917, HPA062908 Supported Tissue enriched 25 skin: 15496.7 breast: 614.2 -ACER1 ASAH3 ENSG00000167769 Alkaline ceramidase 1 19 6306142-6333629 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 skin: 68.0 esophagus: 11.4 -OTUB1 FLJ20113, FLJ40710 ENSG00000167770 OTU deubiquitinase, ubiquitin aldehyde binding 1 11 63985853-64001811 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039176, CAB072836 Approved Supported Approved Nucleus
Cytosol Expressed in all cerebral cortex: 116.3 -RCOR2 ENSG00000167771 REST corepressor 2 11 63911221-63916844 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021638 Uncertain Approved Nucleus
Vesicles
Midbody Tissue enhanced 0 cerebral cortex: 13.2 testis: 3.7 -ANGPTL4 ARP4, FIAF, HFARP, NL2, PGAR, pp1158 ENSG00000167772 Angiopoietin-like 4 19 8363289-8374373 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007879, CAB033770 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 adipose tissue: 78.2 liver: 43.3 -CD320 8D6, 8D6A ENSG00000167775 CD320 molecule 19 8302127-8308356 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014500, HPA073489 Uncertain Approved Cytosol Expressed in all epididymis: 75.7 -SPRYD3 FLJ14800 ENSG00000167778 SPRY domain containing 3 12 53064316-53079420 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039426, HPA039685 Supported Approved Nucleoplasm
Actin filaments
Cytosol Expressed in all cerebral cortex: 145.4 -IGFBP6 ENSG00000167779 Insulin-like growth factor binding protein 6 12 53097436-53102345 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008005 Uncertain Tissue enhanced 0 adipose tissue: 72.2 cervix: 47.7 -SOAT2 ACAT2 ENSG00000167780 Sterol O-acyltransferase 2 12 53103518-53124538 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA062409 Uncertain Tissue enhanced 0 duodenum: 12.4;small intestine: 22.4 spleen: 3.5 -ZNF558 FLJ30932 ENSG00000167785 Zinc finger protein 558 19 8806170-8832328 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003151 Uncertain Mixed parathyroid gland: 18.7 -CABP2 ENSG00000167791 Calcium binding protein 2 11 67518912-67523428 Disease related genes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.1 -NDUFV1 CI-51K ENSG00000167792 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 11 67606852-67612535 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045211, HPA075051 Approved Supported Mitochondria
Cytosol Expressed in all parathyroid gland: 218.0 -CDK2AP2 DOC-1R, p14 ENSG00000167797 Cyclin-dependent kinase 2 associated protein 2 11 67506497-67508649 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047599 Uncertain Approved Nucleoplasm Expressed in all epididymis: 49.8 -NUDT8 FLJ41567 ENSG00000167799 Nudix (nucleoside diphosphate linked moiety X)-type motif 8 11 67627938-67629930 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041252, HPA041466 Supported Approved Nucleoli
Cytosol Expressed in all heart muscle: 21.0 -TBX10 TBX13, TBX7 ENSG00000167800 T-box 10 11 67631303-67639560 Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA047881 Uncertain Group enriched 27 colon: 9.0;duodenum: 6.0;rectum: 8.8;small intestine: 10.8 testis: 0.3 -PRDX2 MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA ENSG00000167815 Peroxiredoxin 2 19 12796820-12801859 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008713 Approved Expressed in all adrenal gland: 471.1 -OR8J3 ENSG00000167822 Olfactory receptor, family 8, subfamily J, member 3 11 56136771-56137718 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -OR5I1 HSOlf1, OLF1 ENSG00000167825 Olfactory receptor, family 5, subfamily I, member 1 11 55935456-55936400 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -ZNF232 ZSCAN11 ENSG00000167840 Zinc finger protein 232 17 5105541-5123116 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027309, HPA028611 Uncertain Supported Nucleus
Vesicles
Cytosol Mixed epididymis: 4.3 -MIS12 hMIS12, KNTC2AP, MGC2488, MTW1 ENSG00000167842 MIS12 kinetochore complex component 17 5486285-5490814 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044482 Approved Expressed in all epididymis: 39.0 -CD300C CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR ENSG00000167850 CD300c molecule 17 74541108-74546143 CD markers, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014523 Approved Tissue enhanced 0 lung: 12.5 appendix: 9.7 -CD300A CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60 ENSG00000167851 CD300a molecule 17 74466416-74484796 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011645 Approved Tissue enhanced 0 spleen: 87.2 appendix: 41.1 -TEKT1 ENSG00000167858 Tektin 1 17 6789133-6831761 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044444, HPA062285 Supported Group enriched 7 fallopian tube: 79.4;testis: 18.3 lung: 7.0 -HID1 C17orf28, DMC1, HID-1 ENSG00000167861 HID1 domain containing 17 74950743-74973166 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023095, HPA031406 Approved Supported Golgi apparatus
Cytosol Expressed in all stomach: 54.0 -ICT1 DS-1 ENSG00000167862 Immature colon carcinoma transcript 1 17 75012670-75021261 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003634 Approved Supported Nucleoplasm
Mitochondria Expressed in all kidney: 35.8 -ATP5H ATP5JD, ATPQ ENSG00000167863 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 17 75038863-75046985 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042777, HPA048459 Supported Supported Nucleoplasm
Mitochondria Expressed in all heart muscle: 622.4 -TMEM88 FLJ20025, MGC71744 ENSG00000167874 Transmembrane protein 88 17 7855065-7856099 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052991 Approved Mixed placenta: 34.0 -EVPL EVPK ENSG00000167880 Envoplakin 17 76004502-76027452 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002220, HPA053969 Approved Supported Intermediate filaments
Cytosol Group enriched 9 esophagus: 77.8;skin: 111.3 duodenum: 11.0 -SRP68 ENSG00000167881 Signal recognition particle 68kDa 17 76038775-76072653 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023303, HPA055617 Approved Validated Focal adhesion sites
Cytosol Expressed in all thyroid gland: 71.7 -MGAT5B FLJ25132, GnT-IX, GnT-VB ENSG00000167889 Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 17 76868456-76950393 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011082 Approved Nucleoplasm
Mitotic spindle Tissue enriched 14 cerebral cortex: 23.2 testis: 1.6 -TMC8 EVER2, EVIN2 ENSG00000167895 Transmembrane channel-like 8 17 78130770-78142968 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047387, HPA054429 Uncertain Uncertain Golgi apparatus Tissue enhanced 0 lymph node: 120.4;spleen: 107.5 appendix: 75.5 -TK1 ENSG00000167900 Thymidine kinase 1, soluble 17 78174075-78187233 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004683 Approved Mixed bone marrow: 45.8 -TMEM68 FLJ32370 ENSG00000167904 Transmembrane protein 68 8 55696424-55773407 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA018216, HPA019173 Uncertain Approved Vesicles Expressed in all fallopian tube: 36.6 -CYP7A1 CYP7 ENSG00000167910 Cytochrome P450, family 7, subfamily A, polypeptide 1 8 58490178-58500236 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 59 liver: 26.0 duodenum: 0.4 -GSDMA FLJ39120, GSDM, GSDM1 ENSG00000167914 Gasdermin A 17 39962973-39977766 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023313, HPA064826 Supported Tissue enriched 7 skin: 58.5 epididymis: 8.1 -KRT24 FLJ20261, MGC138169, MGC138173 ENSG00000167916 Keratin 24, type I 17 40697991-40703750 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022978 Uncertain Approved Intermediate filaments
Cytosol Tissue enhanced 0 esophagus: 28.5;tonsil: 69.8 epididymis: 20.1 -TMEM99 MGC21518 ENSG00000167920 Transmembrane protein 99 17 40819106-40836274 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA076359 Approved Cytosol Tissue enhanced 0 testis: 175.7 epididymis: 52.1 -GHDC LGP1 ENSG00000167925 GH3 domain containing 17 42188799-42194532 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031650 Uncertain Expressed in all spleen: 29.8 -FAM234A C16orf9, DKFZP761D0211, FLJ32603, ITFG3 ENSG00000167930 Family with sequence similarity 234, member A 16 234546-268971 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011651 Uncertain Nucleoplasm
Mitochondria Expressed in all duodenum: 113.8 -SOST VBCH ENSG00000167941 Sclerostin 17 43753731-43758788 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB025660 Approved Tissue enriched 16 kidney: 10.3 lung: 0.6 -PRR25 gs64 ENSG00000167945 Proline rich 25 16 805443-813861 Predicted intracellular proteins No evidence No evidence No evidence HPA042974 Uncertain Not detected adipose tissue: 0.1 -ZNF598 FLJ00086 ENSG00000167962 Zinc finger protein 598 16 1997654-2009823 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041760, HPA041896 Approved Approved Plasma membrane
Cytosol Mixed spleen: 12.4 -RAB26 ENSG00000167964 RAB26, member RAS oncogene family 16 2140803-2154165 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA075624 Uncertain Vesicles
Plasma membrane
Centrosome Tissue enhanced 0 cerebral cortex: 21.2 liver: 11.4 -MLST8 GbetaL, GBL, Lst8, Pop3 ENSG00000167965 MTOR associated protein, LST8 homolog 16 2204248-2209416 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB019935, HPA041841 Approved Approved Nucleoplasm
Golgi apparatus
Cell Junctions Expressed in all testis: 28.7 -E4F1 E4F ENSG00000167967 E4F transcription factor 1 16 2223566-2235742 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052042, HPA071325 Validated Nucleoplasm Expressed in all spleen: 12.8 -DNASE1L2 DNAS1L2 ENSG00000167968 Deoxyribonuclease I-like 2 16 2235816-2238711 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA044714 Approved Mitochondria Tissue enriched 6 skin: 12.0 cerebral cortex: 1.9 -ECI1 DCI ENSG00000167969 Enoyl-CoA delta isomerase 1 16 2239395-2252300 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041746, HPA043227 Supported Expressed in all skeletal muscle: 69.3 -CASKIN1 ANKS5A, KIAA1306 ENSG00000167971 CASK interacting protein 1 16 2177180-2196525 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055990 Supported Approved Nucleus
Cytosol Tissue enriched 34 cerebral cortex: 20.3 testis: 0.6 -ABCA3 ABC-C, ABC3, EST111653, LBM180 ENSG00000167972 ATP-binding cassette, sub-family A (ABC1), member 3 16 2275881-2340746 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007884 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 lung: 135.8 cerebral cortex: 51.7 -KCTD5 FLJ20040 ENSG00000167977 Potassium channel tetramerization domain containing 5 16 2682475-2709030 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all lymph node: 23.4 -SRRM2 Cwc21, KIAA0324, SRL300, SRm300 ENSG00000167978 Serine/arginine repetitive matrix 2 16 2752329-2772538 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041411, HPA066181 Supported Validated Nuclear speckles Expressed in all parathyroid gland: 283.6 -ZNF597 FLJ33071, HIT-4 ENSG00000167981 Zinc finger protein 597 16 3432422-3443542 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA001556 Approved Approved Nucleus
Nucleoli
Cytosol Mixed testis: 7.3 -NLRC3 CLR16.2, FLJ00348, NOD3 ENSG00000167984 NLR family, CARD domain containing 3 16 3539033-3577400 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048062 Supported Microtubule organizing center
Cytosol Tissue enhanced 0 lymph node: 16.7 spleen: 11.8 -SDHAF2 C11orf79, FLJ20487, PGL2, SDH5 ENSG00000167985 Succinate dehydrogenase complex assembly factor 2 11 61430042-61447529 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039464, HPA039732 Supported Supported Nucleoli
Mitochondria
Cytosol Expressed in all fallopian tube: 35.7 -DDB1 ENSG00000167986 Damage-specific DNA binding protein 1, 127kDa 11 61299451-61342596 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032821, HPA045174, HPA068456 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 480.7 -VPS37C FLJ20847 ENSG00000167987 Vacuolar protein sorting 37 homolog C (S. cerevisiae) 11 61130256-61161617 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043348 Approved Approved Nucleus
Vesicles Expressed in all skin: 25.2 -VWCE FLJ32009, URG11, VWC1 ENSG00000167992 Von Willebrand factor C and EGF domains 11 61258286-61295424 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040401, HPA043921 Uncertain Supported Nucleus
Vesicles
Cytosol Tissue enhanced 0 fallopian tube: 5.1;ovary: 5.8 liver: 3.7 -RAB3IL1 GRAB ENSG00000167994 RAB3A interacting protein (rabin3)-like 1 11 61897301-61920269 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039723 Uncertain Approved Cytosol Mixed testis: 48.8 -BEST1 BEST, BMD, RP50, VMD2 ENSG00000167995 Bestrophin 1 11 61949821-61965515 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA057464 Supported Mixed cerebral cortex: 17.0 -FTH1 FHC, FTH, FTHL6, PIG15, PLIF ENSG00000167996 Ferritin, heavy polypeptide 1 11 61959718-61967660 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB008623 Approved Approved Microtubules Expressed in all appendix: 5085.0 -BSCL2 GNG3LG, SPG17 ENSG00000168000 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 11 62690275-62709845 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042394 Approved Expressed in all testis: 249.9 -POLR2G hRPB19, hsRPB7, RPB7 ENSG00000168002 Polymerase (RNA) II (DNA directed) polypeptide G 11 62761544-62766710 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053000 Approved Supported Nucleoplasm Expressed in all fallopian tube: 98.6 -SLC3A2 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE ENSG00000168003 Solute carrier family 3 (amino acid transporter heavy chain), member 2 11 62856102-62888875 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010455, HPA017980 Supported Supported Nucleus
Plasma membrane
Cytosol Expressed in all parathyroid gland: 424.3 -HRASLS5 HRLP5 ENSG00000168004 HRAS-like suppressor family, member 5 11 63461404-63491194 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 5 testis: 95.8 adipose tissue: 17.7 -C11orf84 ENSG00000168005 Chromosome 11 open reading frame 84 11 63813388-63827718 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040128, HPA050313 Uncertain Approved Nuclear speckles Expressed in all testis: 42.7 -ATG16L2 ATG16B, FLJ00012, WDR80 ENSG00000168010 Autophagy related 16-like 2 11 72814308-72843674 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045444, HPA050312 Approved Validated Nucleoplasm Expressed in all spleen: 101.0 -C2CD3 DKFZP586P0123 ENSG00000168014 C2 calcium-dependent domain containing 3 11 74012714-74171210 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038552, HPA038553, HPA040433 Approved Approved Nucleus
Microtubule organizing center Mixed testis: 29.4 -TRANK1 KIAA0342, LBA1 ENSG00000168016 Tetratricopeptide repeat and ankyrin repeat containing 1 3 36826820-36945057 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035508 Approved Approved Nucleoplasm Mixed endometrium: 38.8 -TTC21A IFT139A, STI2 ENSG00000168026 Tetratricopeptide repeat domain 21A 3 39107704-39138903 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035510, HPA035511 Approved Supported Nucleoplasm Tissue enriched 26 testis: 39.3 fallopian tube: 1.4 -RPSA 37LRP, LAMR1, LRP, p40, SA ENSG00000168028 Ribosomal protein SA 3 39406689-39412542 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009561 Approved Supported Plasma membrane
Cytosol Expressed in all ovary: 2079.5 -ENTPD3 CD39L3, HB6, NTPDase-3 ENSG00000168032 Ectonucleoside triphosphate diphosphohydrolase 3 3 40387156-40428619 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071802 Approved Cytosol Tissue enhanced 0 cervix, uterine: 33.4 urinary bladder: 15.2 -CTNNB1 armadillo, beta-catenin, CTNNB ENSG00000168036 Catenin (cadherin-associated protein), beta 1, 88kDa 3 41194837-41260096 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000108, CAB001950, HPA029159, HPA029160 Supported Validated Plasma membrane Expressed in all cervix: 285.2 -ULK4 FAM7C1, FLJ20574, REC01035 ENSG00000168038 Unc-51 like kinase 4 3 41246599-41962430 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017930 Uncertain Approved Nucleoplasm
Mitochondria
Cytosol Tissue enhanced 0 testis: 37.9 parathyroid gland: 14.2 -FADD GIG3, MORT1 ENSG00000168040 Fas (TNFRSF6)-associated via death domain 11 70203163-70207390 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001464, CAB010209 Supported Supported Nucleoplasm
Cytosol Expressed in all placenta: 20.2 -LTBP3 LTBP2 ENSG00000168056 Latent transforming growth factor beta binding protein 3 11 65538560-65558930 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA073170 Approved Nucleoplasm Expressed in all parathyroid gland: 102.2 -NAALADL1 ENSG00000168060 N-acetylated alpha-linked acidic dipeptidase-like 1 11 65044818-65058549 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047123 Approved Uncertain Cytosol Tissue enriched 5 small intestine: 106.2 duodenum: 20.7 -SAC3D1 HSU79266, SHD1 ENSG00000168061 SAC3 domain containing 1 11 65040901-65044828 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042677 Uncertain Approved Cytosol Tissue enhanced 0 testis: 12.8 skin: 3.4 -BATF2 MGC20410 ENSG00000168062 Basic leucine zipper transcription factor, ATF-like 2 11 64987943-64997045 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA062496 Approved Approved Nucleoli Mixed spleen: 17.8 -SLC22A11 OAT4 ENSG00000168065 Solute carrier family 22 (organic anion/urate transporter), member 11 11 64555626-64572875 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026076 Approved Group enriched 134 epididymis: 10.0;kidney: 25.9;placenta: 44.5 seminal vesicle: 0.2 -SF1 ZCCHC25, ZFM1, ZNF162 ENSG00000168066 Splicing factor 1 11 64764606-64778786 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018883 Supported Validated Nucleoplasm Expressed in all bone marrow: 146.1 -MAP4K2 BL44, GCK, RAB8IP ENSG00000168067 Mitogen-activated protein kinase kinase kinase kinase 2 11 64784914-64803241 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007330 Supported Approved Vesicles Mixed spleen: 23.3 -C11orf85 ENSG00000168070 Chromosome 11 open reading frame 85 11 64937517-64972085 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 9 testis: 41.3 gallbladder: 4.5 -CCDC88B BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3 ENSG00000168071 Coiled-coil domain containing 88B 11 64340223-64357534 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026652 Approved Approved Nucleoplasm
Centrosome
Cytosol Tissue enhanced 0 spleen: 36.9 lymph node: 31.6 -SCARA3 APC7, CSR, CSR1, MSLR1, MSRL1 ENSG00000168077 Scavenger receptor class A, member 3 8 27633868-27676776 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029861, HPA047386 Uncertain Supported Endoplasmic reticulum Tissue enhanced 0 fallopian tube: 150.2 smooth muscle: 107.0 -PBK CT84, FLJ14385, Nori-3, SPK, TOPK ENSG00000168078 PDZ binding kinase 8 27809620-27838095 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005753, HPA050656 Supported Supported Approved Cytosol Tissue enriched 8 testis: 108.5 lymph node: 13.5 -SCARA5 FLJ23907, MGC45780, NET33 ENSG00000168079 Scavenger receptor class A, member 5 8 27869882-27992727 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024661 Approved Mixed adipose tissue: 65.7 -PNOC N/OFQ, NOP, PPNOC ENSG00000168081 Prepronociceptin 8 28316986-28343355 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044507, HPA056724 Supported Tissue enhanced 0 cerebral cortex: 44.3;fallopian tube: 26.0;lymph node: 29.3 tonsil: 22.9 -COPS6 CSN6, MOV34-34KD ENSG00000168090 COP9 signalosome subunit 6 7 100088954-100092200 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044315 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 127.1 -PAFAH1B2 ENSG00000168092 Platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 11 117144267-117176894 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051836 Approved Supported Nucleoli
Plasma membrane
Cytosol Expressed in all cerebral cortex: 68.4 -ANKS3 FLJ32345, FLJ32767, KIAA1977 ENSG00000168096 Ankyrin repeat and sterile alpha motif domain containing 3 16 4696510-4734378 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041409, HPA041482 Uncertain Supported Nucleoplasm
Cytosol Mixed ovary: 8.0 -NUDT16L1 SDOS ENSG00000168101 Nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 16 4693694-4695859 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044186, HPA063605 Approved Approved Plasma membrane
Cytosol Expressed in all prostate: 28.4 -KIAA1586 ENSG00000168116 KIAA1586 6 57046532-57055239 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036370 Approved Approved Nucleus
Nuclear membrane Mixed testis: 14.0 -RAB4A HRES-1/RAB4, RAB4 ENSG00000168118 RAB4A, member RAS oncogene family 1 229271062-229305894 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all prostate: 57.2 -OR1F1 Olfmf, OR16-36, OR16-37, OR16-88, OR16-89, OR16-90, OR1F10, OR1F13P, OR1F4, OR1F5, OR1F6, OR1F7, OR1F8, OR1F9, OR3-145 ENSG00000168124 Olfactory receptor, family 1, subfamily F, member 1 16 3204247-3205188 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.7 -OR2B2 hs6M1-10, OR2B2Q, OR2B9, OR6-1 ENSG00000168131 Olfactory receptor, family 2, subfamily B, member 2 6 27911185-27912396 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -KCNJ4 HIR, hIRK2, HRK1, IRK3, Kir2.3 ENSG00000168135 Potassium channel, inwardly rectifying subfamily J, member 4 22 38426327-38455199 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 25 cerebral cortex: 41.0;heart muscle: 11.7 gallbladder: 1.0 -SETD5 FLJ10707 ENSG00000168137 SET domain containing 5 3 9397615-9479240 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017093, HPA035574 Approved Validated Nucleus
Cytosol Expressed in all parathyroid gland: 42.0 -VASN SLITL2 ENSG00000168140 Vasorin 16 4371848-4383528 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011246 Uncertain Mixed placenta: 16.0 -FAM83B C6orf143, FLJ30642 ENSG00000168143 Family with sequence similarity 83, member B 6 54846771-54942022 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031464, HPA031465 Approved Tissue enhanced 0 skin: 27.4 esophagus: 17.8 -HIST3H3 H3.4, H3/g, H3FT, H3t ENSG00000168148 Histone cluster 3, H3 1 228424845-228425325 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001386, CAB003812, HPA042570 Supported Supported Nucleoplasm Tissue enriched 9 testis: 2.1 fallopian tube: 0.2 -THAP9 FLJ34093 ENSG00000168152 THAP domain containing 9 4 82900684-82919969 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037420, HPA037421 Uncertain Approved Mitochondria Mixed testis: 11.4 -OR2C1 OLFmf3, OR2C2P ENSG00000168158 Olfactory receptor, family 2, subfamily C, member 1 16 3355889-3357294 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 1.1 parathyroid gland: 0.4 -RNF187 ENSG00000168159 Ring finger protein 187 1 228487061-228495766 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030098 Approved Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 109.4 -HOOK3 HK3 ENSG00000168172 Hook microtubule-tethering protein 3 8 42896932-43030539 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024756 Approved Supported Golgi apparatus
Microtubule organizing center
Cytosol Mixed thyroid gland: 36.4 -MAPK1IP1L C14orf32 ENSG00000168175 Mitogen-activated protein kinase 1 interacting protein 1-like 14 55051631-55070192 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034506 Uncertain Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 53.3 -DDIT4 Dig2, FLJ20500, REDD-1, REDD1, RTP801 ENSG00000168209 DNA-damage-inducible transcript 4 10 72273920-72276036 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034507, HPA034508 Approved Supported Cytosol Expressed in all ovary: 220.2 -RBPJ CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH ENSG00000168214 Recombination signal binding protein for immunoglobulin kappa J region 4 26163455-26435131 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060647 Supported Nucleoplasm Expressed in all placenta: 76.7 -LMBRD1 bA810I22.1, C6orf209, cblF, FLJ11240 ENSG00000168216 LMBR1 domain containing 1 6 69675802-69797111 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019547 Uncertain Expressed in all parathyroid gland: 170.0 -ZCCHC4 FLJ23024, HSPC052, ZGRF4 ENSG00000168228 Zinc finger, CCHC domain containing 4 4 25312785-25370383 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035575, HPA035576 Uncertain Approved Nuclear speckles
Golgi apparatus Mixed testis: 8.2 -PTGDR DP, DP1, PTGDR1 ENSG00000168229 Prostaglandin D2 receptor (DP) 14 52267713-52276724 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 rectum: 8.7;spleen: 8.9 colon: 5.7 -TTC39C C18orf17, FLJ33761, HsT2697 ENSG00000168234 Tetratricopeptide repeat domain 39C 18 23992773-24135610 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA065705, HPA065713 Approved Approved Nucleoplasm Expressed in all liver: 47.6 -GLYCTK HBEBP2, HBEBP4 ENSG00000168237 Glycerate kinase 3 52287089-52293476 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006913 Approved Approved Golgi apparatus
Cytosol
Rods & Rings Tissue enhanced 0 duodenum: 39.3;liver: 60.5 small intestine: 32.4 -GNG4 ENSG00000168243 Guanine nucleotide binding protein (G protein), gamma 4 1 235547687-235650754 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 25.4;ovary: 18.3;prostate: 17.5 endometrium: 8.3 -UBTD2 DC-UbP, MGC30022 ENSG00000168246 Ubiquitin domain containing 2 5 172209640-172284071 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035891, HPA035892 Uncertain Mixed testis: 53.1 -POLR2J3 ENSG00000168255 Polymerase (RNA) II (DNA directed) polypeptide J3 7 102537918-102572656 Predicted intracellular proteins, RNA polymerase related proteins Evidence at transcript level Evidence at transcript level HPA011403, HPA042997, HPA044010, HPA046970 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 58.6 -NKIRAS2 DKFZP434N1526, kappaB-Ras2, KBRAS2 ENSG00000168256 NFKB inhibitor interacting Ras-like 2 17 42011382-42025644 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062861 Approved Nucleus
Nucleoli Expressed in all placenta: 49.2 -DNAJC7 TPR2, TTC2 ENSG00000168259 DnaJ (Hsp40) homolog, subfamily C, member 7 17 41976433-42021376 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023015, HPA052395 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 75.0 -KCNV2 Kv8.2 ENSG00000168263 Potassium channel, voltage gated modifier subfamily V, member 2 9 2717502-2730037 Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031131 Uncertain Tissue enriched 44 testis: 6.6 skin: 0.1 -IRF2BP2 IRF-2BP2 ENSG00000168264 Interferon regulatory factor 2 binding protein 2 1 234604269-234609525 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027815, HPA062269 Approved Validated Nucleoplasm Expressed in all bone marrow: 98.9 -PTF1A bHLHa29, PTF1-p48 ENSG00000168267 Pancreas specific transcription factor, 1a 10 23192327-23194252 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022612 Approved Nucleoplasm Tissue enriched 6 pancreas: 7.7 testis: 1.2 -NT5DC2 FLJ12442 ENSG00000168268 5'-nucleotidase domain containing 2 3 52524385-52535054 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050683 Approved Expressed in all adrenal gland: 96.5 -FOXI1 FKHL10, FREAC6 ENSG00000168269 Forkhead box I1 5 170105897-170109725 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA071469 Supported Uncertain Nucleoli
Vesicles Tissue enhanced 0 breast: 10.4;kidney: 19.9;prostate: 6.5 salivary gland: 6.3 -SMIM4 C3orf78 ENSG00000168273 Small integral membrane protein 4 3 52534013-52579237 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047771 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all adrenal gland: 102.7 -COA6 C1orf31 ENSG00000168275 Cytochrome c oxidase assembly factor 6 1 234373456-234384049 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028588 Approved Supported Mitochondria Expressed in all duodenum: 46.7 -KIF5C ENSG00000168280 Kinesin family member 5C 2 148875250-149026759 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035210 Approved Approved Nucleoli
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 205.9 prostate: 42.3 -MGAT2 GNT-II ENSG00000168282 Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 14 49620795-49623481 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043721, HPA056824 Approved Supported Golgi apparatus Expressed in all testis: 44.8 -BMI1 PCGF4, RNF51 ENSG00000168283 BMI1 proto-oncogene, polycomb ring finger 10 22321211-22331484 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011120, HPA030471, HPA030472 Supported Approved Nucleus
Nucleoli
Nuclear bodies
Cytosol Expressed in all parathyroid gland: 84.7 -THAP11 CTG-B43a, CTG-B45d, HRIHFB2206 ENSG00000168286 THAP domain containing 11 16 67842082-67844195 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041434, HPA042189 Supported Validated Nucleoplasm
Cytokinetic bridge Expressed in all fallopian tube: 25.1 -MMADHC C2orf25, cblD, CL25022 ENSG00000168288 Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2 149569634-149587816 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037531, HPA037532 Supported Expressed in all testis: 122.3 -PDHB ENSG00000168291 Pyruvate dehydrogenase (lipoamide) beta 3 58427630-58433857 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033794, HPA036744, HPA036745 Supported Supported Nucleoplasm
Mitochondria Expressed in all heart muscle: 111.5 -PXK FLJ20335 ENSG00000168297 PX domain containing serine/threonine kinase 3 58332880-58426126 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024068 Supported Supported Plasma membrane
Microtubule organizing center
Cytosol Expressed in all thyroid gland: 124.3 -HIST1H1E H1.4, H1e, H1F4, H1s-4 ENSG00000168298 Histone cluster 1, H1e 6 26156354-26157107 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011506, HPA055907 Supported Supported Nuclear speckles Tissue enriched 11 bone marrow: 36.3 lymph node: 3.4 -PCMTD1 FLJ10883 ENSG00000168300 Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 8 51817575-51899186 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025696, HPA061444 Approved Approved Nucleoplasm
Plasma membrane Expressed in all parathyroid gland: 184.0 -KCTD6 KCASH3, MGC27385 ENSG00000168301 Potassium channel tetramerization domain containing 6 3 58492114-58502360 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036100, HPA036101 Uncertain Approved Nucleoli
Mitochondria Expressed in all cerebral cortex: 40.3 -MPLKIP C7orf11, ORF20, TTDN1 ENSG00000168303 M-phase specific PLK1 interacting protein 7 40126023-40134659 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058457, HPA065463 Uncertain Supported Nucleoplasm
Golgi apparatus
Vesicles Mixed liver: 4.3 -ACOX2 BRCACOX, BRCOX, THCCox ENSG00000168306 Acyl-CoA oxidase 2, branched chain 3 58505136-58537319 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038280, HPA064845 Approved Supported Vesicles
Mitochondria Tissue enhanced 0 liver: 87.8 kidney: 42.3 -FAM107A DRR1, TU3A ENSG00000168309 Family with sequence similarity 107, member A 3 58564117-58627610 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055888 Approved Approved Nuclear speckles Group enriched 5 cerebral cortex: 487.1;fallopian tube: 123.9 epididymis: 56.9 -IRF2 ENSG00000168310 Interferon regulatory factor 2 4 184387713-184474580 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030813, CAB032306, HPA057327 Supported Validated Nucleoplasm
Cytosol Expressed in all spleen: 75.4 -MOBP ENSG00000168314 Myelin-associated oligodendrocyte basic protein 3 39467198-39529479 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035152 Supported Tissue enriched 8 cerebral cortex: 176.4 parathyroid gland: 21.9 -CX3CR1 CCRL1, CMKBRL1, CMKDR1, GPR13, V28 ENSG00000168329 Chemokine (C-X3-C motif) receptor 1 3 39263494-39281735 Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB032478, HPA046587 Approved Tissue enhanced 0 cerebral cortex: 59.4 spleen: 16.8 -C8orf22 ENSG00000168333 Chromosome 8 open reading frame 22 8 49054311-49076090 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA060329 Uncertain Tissue enriched 88 skeletal muscle: 362.2 esophagus: 4.1 -XIRP1 CMYA1, DKFZp451D042, Xin ENSG00000168334 Xin actin binding repeat containing 1 3 39183210-39192596 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016750, HPA018458, CAB026391 Supported Approved Nucleus
Actin filaments Group enriched 14 heart muscle: 105.4;skeletal muscle: 58.4 esophagus: 6.0 -INSM2 IA-6 ENSG00000168348 Insulinoma-associated 2 14 35534042-35537054 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA044885, HPA051925 Uncertain Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 1.3 testis: 0.7 -DEGS2 C14orf66, DES2, FADS8 ENSG00000168350 Delta(4)-desaturase, sphingolipid 2 14 100143957-100160163 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046644 Approved Nucleus
Nucleoli Tissue enhanced 0 skin: 31.3;small intestine: 39.5 duodenum: 25.5 -SCN11A NaN, Nav1.9, SCN12A, SNS-2 ENSG00000168356 Sodium channel, voltage gated, type XI alpha subunit 3 38845769-38950561 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA036746, HPA036747 Uncertain Tissue enhanced 0 placenta: 3.7;spleen: 5.4 testis: 2.1 -ARF4 ARF2 ENSG00000168374 ADP-ribosylation factor 4 3 57571363-57598220 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cervix: 325.0 -SEPT2 DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3 ENSG00000168385 Septin 2 2 241315100-241354027 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017190, HPA018481 Supported Supported Nucleus
Actin filaments
Cytosol Expressed in all thyroid gland: 368.1 -FILIP1L DOC-1, GIP130 ENSG00000168386 Filamin A interacting protein 1-like 3 99830141-100114513 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043133 Approved Approved Plasma membrane Mixed smooth muscle: 214.9 -MFSD2A FLJ14490, MFSD2 ENSG00000168389 Major facilitator superfamily domain containing 2A 1 39955112-39969968 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043107 Uncertain Approved Plasma membrane
Cytosol
Cytoplasmic bodies Tissue enhanced 0 epididymis: 114.6;seminal vesicle: 109.6 testis: 63.3 -DTYMK CDC8, TMPK, TYMK ENSG00000168393 Deoxythymidylate kinase (thymidylate kinase) 2 241675742-241686991 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042593, HPA042719 Approved Approved Mitochondria Expressed in all lymph node: 24.3 -TAP1 ABCB2, D6S114E, PSF1, RING4 ENSG00000168394 Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 6 32845209-32853978 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009516, HPA072354 Approved Supported Endoplasmic reticulum
Microtubule organizing center Mixed appendix: 20.6 -ING5 FLJ23842, p28ING5 ENSG00000168395 Inhibitor of growth family, member 5 2 241702035-241729478 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042685 Approved Expressed in all thyroid gland: 22.0 -ATG4B APG4B, AUTL1, DKFZp586D1822, KIAA0943 ENSG00000168397 Autophagy related 4B, cysteine peptidase 2 241637213-241673857 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037195, HPA069803 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 43.9 -BDKRB2 BK-2 ENSG00000168398 Bradykinin receptor B2 14 96204679-96244166 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA050841 Approved Mixed gallbladder: 32.6 -MLKL FLJ34389 ENSG00000168404 Mixed lineage kinase domain-like 16 74671855-74700960 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed spleen: 29.4 -RFWD3 FLJ10520, RNF201 ENSG00000168411 Ring finger and WD repeat domain 3 16 74621394-74666881 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048258, HPA075649 Supported Nucleoplasm
Cytosol Mixed testis: 46.7 -MTNR1A MEL-1A-R ENSG00000168412 Melatonin receptor 1A 4 186533655-186555567 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 kidney: 2.2;testis: 1.9 colon: 1.2 -KCNG4 Kv6.4 ENSG00000168418 Potassium channel, voltage gated modifier subfamily G, member 4 16 84218667-84239750 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level No evidence Evidence at protein level HPA039161 Uncertain Not detected adrenal gland: 0.6 -RHOH ARHH, RhoH, TTF ENSG00000168421 Ras homolog family member H 4 40191053-40246967 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030345 Uncertain Tissue enhanced 0 lymph node: 99.6;tonsil: 80.6 appendix: 49.4 -KLHL30 FLJ43374 ENSG00000168427 Kelch-like family member 30 2 238138722-238152947 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062095 Approved Microtubule organizing center Tissue enhanced 0 skeletal muscle: 22.1 heart muscle: 5.8 -COG7 ENSG00000168434 Component of oligomeric golgi complex 7 16 23388493-23453180 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040758, HPA064645 Uncertain Validated Golgi apparatus Expressed in all parathyroid gland: 30.4 -CDC40 EHB3, FLJ10564, PRP17, PRPF17 ENSG00000168438 Cell division cycle 40 6 110180141-110254275 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046620 Supported Nucleus Expressed in all thyroid gland: 27.0 -STIP1 HOP, STI1 ENSG00000168439 Stress-induced phosphoprotein 1 11 64185272-64204543 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017448, HPA039291, HPA044062 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 219.7 -SCNN1B ENaCbeta ENSG00000168447 Sodium channel, non voltage gated 1 beta subunit 16 23278231-23381299 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA015612 Uncertain Tissue enhanced 0 cervix, uterine: 71.5 esophagus: 45.0 -HR ALUNC, AU ENSG00000168453 Hair growth associated 8 22114415-22133384 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054888 Supported Nucleoplasm Tissue enhanced 0 skin: 59.1 cerebral cortex: 11.9 -TXNDC2 SPTRX1 ENSG00000168454 Thioredoxin domain containing 2 (spermatozoa) 18 9885726-9889275 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB016414, HPA018817 Supported Validated Nucleus
Cytosol Tissue enriched 476 testis: 142.8 smooth muscle: 0.2 -RAB31 Rab22B ENSG00000168461 RAB31, member RAS oncogene family 18 9708165-9862551 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019717 Approved Expressed in all cerebral cortex: 170.3 -REEP4 C8orf20, FLJ22246, FLJ22277, PP432 ENSG00000168476 Receptor accessory protein 4 8 22138020-22141951 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042683 Approved Approved Cytosol Expressed in all skin: 66.5 -TNXB TNXB1, TNXB2, TNXBS, XB, XBS ENSG00000168477 Tenascin XB 6 32041154-32115334 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA070464 Approved Vesicles Tissue enhanced 0 adrenal gland: 92.0 endometrium: 18.7 -LGI3 ENSG00000168481 Leucine-rich repeat LGI family, member 3 8 22146825-22157084 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024826 Approved Cytosol Group enriched 7 cerebral cortex: 76.2;lung: 23.9;skin: 17.4;thyroid gland: 21.5 esophagus: 5.2 -SFTPC BRICD6, PSP-C, SFTP2, SMDP2, SP-C ENSG00000168484 Surfactant protein C 8 22156913-22164479 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009313, HPA010928 Supported Tissue enriched 832 lung: 25336.5 adrenal gland: 30.4 -BMP1 PCOLC ENSG00000168487 Bone morphogenetic protein 1 8 22164736-22212326 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014572 Approved Tissue enhanced 0 placenta: 21.0 smooth muscle: 10.4 -ATXN2L A2D, A2lp ENSG00000168488 Ataxin 2-like 16 28823035-28837237 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041506, HPA043391, HPA071955 Approved Validated Cytosol Expressed in all testis: 187.5 -PHYHIP DYRK1AP3, KIAA0273, PAHX-AP ENSG00000168490 Phytanoyl-CoA 2-hydroxylase interacting protein 8 22219704-22232341 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068030, HPA069318 Approved Supported Mitochondria Tissue enhanced 0 cerebral cortex: 183.2;skin: 58.3 adrenal gland: 29.0 -CCDC110 CT52, KM-HN-1, MGC33607 ENSG00000168491 Coiled-coil domain containing 110 4 185445182-185471759 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 14 testis: 187.1 thyroid gland: 13.4 -POLR3D BN51T, RPC4, TSBN51 ENSG00000168495 Polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 8 22245104-22254600 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061331, HPA067875, HPA068461, HPA069089 Supported Validated Nucleoplasm Expressed in all testis: 24.6 -FEN1 FEN-1, MF1, RAD2 ENSG00000168496 Flap structure-specific endonuclease 1 11 61792637-61797244 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002262, HPA006581, HPA006748 Supported Approved Nucleus
Nucleoli
Plasma membrane
Mitochondria Mixed lymph node: 35.2 -SDPR cavin-2, CAVIN2, PS-p68, SDR ENSG00000168497 Serum deprivation response 2 191834302-191847255 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039325, HPA062122 Supported Supported Plasma membrane
Cytosol Expressed in all adipose tissue: 165.5 -MTCL1 CCDC165, KIAA0802, SOGA2 ENSG00000168502 Microtubule crosslinking factor 1 18 8705661-8832778 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046245 Uncertain Approved Nucleoplasm
Cytokinetic bridge Mixed gallbladder: 12.8 -GBX2 ENSG00000168505 Gastrulation brain homeobox 2 2 236165236-236168369 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA067809 Supported Nucleoplasm Not detected cerebral cortex: 0.6 -HFE2 haemojuvelin, hemojuvelin, HFE2A, HJV, JH, RGMC ENSG00000168509 Hemochromatosis type 2 (juvenile) 1 146017468-146021918 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 15 heart muscle: 47.4;liver: 123.1;skeletal muscle: 213.2 esophagus: 8.6 -SCGB1D1 LIPA, LPHA, MGC71958 ENSG00000168515 Secretoglobin, family 1D, member 1 11 62190216-62193539 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cervix, uterine: 2.0;fallopian tube: 1.4 epididymis: 0.8 -HEXIM2 FLJ32384 ENSG00000168517 Hexamethylene bis-acetamide inducible 2 17 45160700-45170040 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023323, HPA028455 Supported Supported Nucleoplasm
Nuclear speckles Expressed in all testis: 46.8 -FNTA FPTA, PGGT1A, PTAR2 ENSG00000168522 Farnesyltransferase, CAAX box, alpha 8 43034194-43085788 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010149, HPA018830 Approved Approved Cytosol Expressed in all placenta: 62.5 -SERINC2 FKSG84, PRO0899, TDE2, TDE2L ENSG00000168528 Serine incorporator 2 1 31409565-31434680 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA005974 Approved Mixed urinary bladder: 138.8 -MYL1 ENSG00000168530 Myosin, light chain 1, alkali; skeletal, fast 2 210290150-210315190 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046859, HPA063034 Uncertain Tissue enriched 33 skeletal muscle: 7523.2 esophagus: 226.9 -TRAPPC11 C4orf41, FLJ12716, foigr, gry ENSG00000168538 Trafficking protein particle complex 11 4 183659267-183713594 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045427 Approved Nucleoplasm
Nuclear membrane Expressed in all parathyroid gland: 36.6 -CHRM1 ENSG00000168539 Cholinergic receptor, muscarinic 1 11 62908679-62921807 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014101, CAB022366 Supported Approved Nucleus
Cytosol Group enriched 6 cerebral cortex: 40.0;prostate: 40.1;salivary gland: 11.1 breast: 4.7 -COL3A1 EDS4A ENSG00000168542 Collagen, type III, alpha 1 2 188974320-189012746 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007583, CAB016766, CAB059993 Approved Tissue enhanced 0 cervix, uterine: 3775.6;gallbladder: 3342.8;smooth muscle: 2989.6 placenta: 2748.0 -GFRA2 GDNFRB, NTNRA, RETL2, TRNR2 ENSG00000168546 GDNF family receptor alpha 2 8 21690403-21812357 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024704, CAB032791 Uncertain Uncertain Vesicles Tissue enhanced 0 thyroid gland: 13.3 spleen: 9.7 -ING2 ING1L, p33ING2 ENSG00000168556 Inhibitor of growth family, member 2 4 183504994-183511096 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019486, HPA021517 Supported Supported Nucleoplasm
Golgi apparatus
Cytosol Expressed in all ovary: 63.1 -CDKN2AIP CARF, FLJ20036 ENSG00000168564 CDKN2A interacting protein 4 183444591-183448198 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041397, HPA062142 Approved Validated Nucleoplasm Expressed in all testis: 37.5 -SNRNP48 C6orf151, dJ336K20B.1, dJ512B11.2, FLJ32234 ENSG00000168566 Small nuclear ribonucleoprotein 48kDa (U11/U12) 6 7590199-7611967 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029234 Approved Supported Nucleoplasm
Cytosol Mixed endometrium: 10.7 -TMEM223 MGC3196 ENSG00000168569 Transmembrane protein 223 11 62771629-62792021 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014504 Approved Approved Nucleus
Nuclear membrane
Mitochondria Expressed in all prostate: 16.9 -SLC20A2 Glvr-2, GLVR2, MLVAR, PiT-2 ENSG00000168575 Solute carrier family 20 (phosphate transporter), member 2 8 42416475-42541926 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026540 Approved Expressed in all thyroid gland: 137.7 -CRYGA CRY-g-A, CRYG1, CRYG5 ENSG00000168582 Crystallin, gamma A 2 208160740-208163576 Predicted intracellular proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected testis: 0.1 -DYNLRB2 DNCL2B, DNLC2B, ROBLD2 ENSG00000168589 Dynein, light chain, roadblock-type 2 16 80540734-80550760 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 8 fallopian tube: 133.1;testis: 323.7 epididymis: 27.0 -TMUB2 MGC3123 ENSG00000168591 Transmembrane and ubiquitin-like domain containing 2 17 44186970-44191731 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043137 Approved Approved Vesicles
Cytosol Expressed in all testis: 48.5 -ADAM29 CT73, svph1 ENSG00000168594 ADAM metallopeptidase domain 29 4 174829668-174978180 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 80 testis: 72.8 endometrium: 0.9 -STAT3 APRF ENSG00000168610 Signal transducer and activator of transcription 3 (acute-phase response factor) 17 42313324-42388568 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001671, CAB003859, HPA058603, CAB068241, CAB068242 Supported Supported Nucleoplasm
Cytosol Expressed in all gallbladder: 127.9 -ZSWIM1 C20orf162, dJ337O18.5 ENSG00000168612 Zinc finger, SWIM-type containing 1 20 45881227-45885266 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041147, HPA046751 Uncertain Approved Plasma membrane
Cytosol Expressed in all parathyroid gland: 10.6 -ADAM9 CORD9, KIAA0021, MCMP, MDC9, Mltng ENSG00000168615 ADAM metallopeptidase domain 9 8 38996869-39105144 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004000 Approved Endoplasmic reticulum
Vesicles Expressed in all parathyroid gland: 116.7 -ADAM18 ADAM27, tMDCIII ENSG00000168619 ADAM metallopeptidase domain 18 8 39584489-39730064 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 84 testis: 8.3 epididymis: 0.0 -GDNF ATF1, ATF2, HFB1-GDNF ENSG00000168621 Glial cell derived neurotrophic factor 5 37812677-37839686 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB005210, HPA070283 Supported Approved Nucleoplasm
Vesicles Mixed placenta: 6.9 -DPCR1 bCX105N19.6, PBLT ENSG00000168631 Diffuse panbronchiolitis critical region 1 6 30940972-30954221 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014036 Approved Tissue enriched 12 stomach: 191.9 gallbladder: 16.1 -WFDC13 C20orf138, dJ601O1.3, WAP13 ENSG00000168634 WAP four-disulfide core domain 13 20 45702016-45708817 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 296 epididymis: 105.3 seminal vesicle: 0.3 -AXIN2 DKFZp781B0869, MGC126582 ENSG00000168646 Axin 2 17 65528563-65561647 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB012283, CAB017783 Approved Uncertain Nucleus
Plasma membrane
Cytosol Mixed endometrium: 31.0 -NDUFS5 CI-15k ENSG00000168653 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 1 39026318-39034636 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042582 Supported Approved Nucleus
Cytosol Expressed in all epididymis: 631.1 -VWA3B DKFZp686F2227, MGC26733 ENSG00000168658 Von Willebrand factor A domain containing 3B 2 98087116-98313299 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036700, HPA036701 Approved Approved Nucleus Group enriched 9 fallopian tube: 40.6;testis: 36.3 lung: 4.3 -ZNF30 DKFZp686N19164, FLJ20562, KOX28 ENSG00000168661 Zinc finger protein 30 19 34926903-34945170 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030400 Uncertain Approved Nucleoplasm
Cytosol Mixed fallopian tube: 5.0 -UGT3A2 ENSG00000168671 UDP glycosyltransferase 3 family, polypeptide A2 5 36035017-36071358 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059475 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 skin: 11.9;testis: 4.6 bone marrow: 3.3 -FAM84B BCMP101, NSE2 ENSG00000168672 Family with sequence similarity 84, member B 8 126552442-126558393 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050782, HPA062115 Approved Approved Nucleoplasm Mixed kidney: 29.4 -LDLRAD4 C18orf1 ENSG00000168675 Low density lipoprotein receptor class A domain containing 4 18 13217498-13652755 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA047633, HPA054556, HPA065246 Approved Supported Nucleoplasm
Vesicles Mixed cerebral cortex: 27.6 -KCTD19 FLJ40162 ENSG00000168676 Potassium channel tetramerization domain containing 19 16 67289428-67326763 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049310, HPA053321 Uncertain Tissue enriched 15 testis: 39.1 bone marrow: 2.7 -SLC16A4 MCT4, MCT5 ENSG00000168679 Solute carrier family 16, member 4 1 110362848-110391082 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046986, HPA060163 Approved Approved Microtubules
Cytokinetic bridge
Cytosol Tissue enhanced 0 kidney: 124.3 placenta: 39.9 -IL7R CD127 ENSG00000168685 Interleukin 7 receptor 5 35852695-35879603 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010215 Approved Supported Plasma membrane Expressed in all appendix: 188.9 -TMEM208 HSPC171 ENSG00000168701 Transmembrane protein 208 16 67227103-67229278 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041868, HPA041949 Supported Expressed in all parathyroid gland: 88.4 -LRP1B LRP-DIT, LRPDIT ENSG00000168702 Low density lipoprotein receptor-related protein 1B 2 140231423-142131701 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069094, HPA074788 Approved Uncertain Vesicles Tissue enhanced 0 cerebral cortex: 16.5;thyroid gland: 9.6 epididymis: 2.7 -WFDC12 C20orf122, dJ211D12.4, WAP2 ENSG00000168703 WAP four-disulfide core domain 12 20 45123425-45124465 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 9 skin: 49.9 seminal vesicle: 5.3 -AHCYL1 IRBIT, PPP1R78, XPVKONA ENSG00000168710 Adenosylhomocysteinase-like 1 1 109984686-110023741 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042589 Approved Supported Cytosol Expressed in all cerebral cortex: 254.6 -DNAJC21 DNAJA5, GS3, JJJ1 ENSG00000168724 DnaJ (Hsp40) homolog, subfamily C, member 21 5 34929593-34958964 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040789, HPA049208 Approved Approved Vesicles Expressed in all testis: 101.2 -PKIG ENSG00000168734 Protein kinase (cAMP-dependent, catalytic) inhibitor gamma 20 44531785-44624247 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042703, HPA063690 Uncertain Supported Nucleoplasm
Cytosol Expressed in all heart muscle: 176.3 -NPNT EGFL6L, POEM ENSG00000168743 Nephronectin 4 105894775-106004027 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003711, HPA050203 Supported Approved Nucleus
Cell Junctions
Cytosol Tissue enhanced 0 lung: 168.7;thyroid gland: 274.6 prostate: 126.2 -LINC01620 C20orf62, dJ1013A22.3 ENSG00000168746 Long intergenic non-protein coding RNA 1620 20 44451984-44465344 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA041142 Uncertain Not detected skin: 0.1 -CA7 ENSG00000168748 Carbonic anhydrase VII 16 66844379-66854153 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047237 Uncertain Tissue enhanced 0 colon: 55.7;rectum: 51.1 small intestine: 10.9 -FAM178B LOC51252 ENSG00000168754 Family with sequence similarity 178, member B 2 96875882-96986592 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042516, HPA062110 Uncertain Uncertain Nuclear speckles
Golgi apparatus Group enriched 5 bone marrow: 11.4;epididymis: 6.6;spleen: 17.0;testis: 7.4 fallopian tube: 2.0 -TSPY2 TSPYQ1 ENSG00000168757 Testis specific protein, Y-linked 2 Y 6246223-6249019 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA049384 Supported Tissue enriched 96 testis: 13.5 adipose tissue: 0.1 -SEMA4C Semacl1, Semaf, SEMAI ENSG00000168758 Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 2 96859716-96870757 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011090 Approved Expressed in all placenta: 63.0 -CNNM3 ACDP3 ENSG00000168763 Cyclin and CBS domain divalent metal cation transport mediator 3 2 96816245-96833911 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016711 Supported Approved Cytosol Expressed in all parathyroid gland: 42.9 -GSTM4 ENSG00000168765 Glutathione S-transferase mu 4 1 109656081-109674836 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048652, HPA055972, HPA055973 Approved Approved Mitochondria Expressed in all duodenum: 153.8 -TET2 FLJ20032, KIAA1546 ENSG00000168769 Tet methylcytosine dioxygenase 2 4 105145875-105279816 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043135 Supported Approved Nucleoplasm Mixed bone marrow: 15.8 -CXXC4 IDAX ENSG00000168772 CXXC finger protein 4 4 104468312-104494901 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036600, HPA036925 Uncertain Uncertain Nucleus
Golgi apparatus Tissue enhanced 0 cerebral cortex: 8.9 thyroid gland: 4.1 -TCTN2 C12orf38, FLJ12975, MKS8, TECT2 ENSG00000168778 Tectonic family member 2 12 123671113-123708403 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039900 Approved Approved Golgi apparatus
Vesicles Mixed fallopian tube: 46.1 -SHOX2 OG12, OG12X, SHOT ENSG00000168779 Short stature homeobox 2 3 158095954-158106503 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adipose tissue: 4.1;testis: 3.3 cervix: 2.8 -PPIP5K1 HISPPD2A, IPS1, KIAA0377, VIP1 ENSG00000168781 Diphosphoinositol pentakisphosphate kinase 1 15 43533462-43590253 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039380 Approved Supported Cytosol Expressed in all parathyroid gland: 52.1 -TSPAN5 NET-4, TM4SF9, Tspan-5 ENSG00000168785 Tetraspanin 5 4 98470367-98658629 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 76.1 ovary: 57.0 -OR12D2 hs6M1-20 ENSG00000168787 Olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 6 29396700-29397623 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -ABHD15 ENSG00000168792 Abhydrolase domain containing 15 17 29560547-29567137 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014470 Approved Approved Nucleoplasm
Cytosol Mixed adipose tissue: 20.5 -ZBTB5 KIAA0354 ENSG00000168795 Zinc finger and BTB domain containing 5 9 37438114-37465399 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA021521 Approved Approved Nucleoplasm
Nuclear bodies
Golgi apparatus Expressed in all thyroid gland: 17.6 -CHTF8 CTF8, DERPC, FLJ20400 ENSG00000168802 Chromosome transmission fidelity factor 8 16 69118010-69132584 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051872, HPA065522 Approved Validated Nucleoplasm Expressed in all fallopian tube: 111.5 -ADAL ENSG00000168803 Adenosine deaminase-like 15 43330674-43354555 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046215, HPA048175 Approved Approved Microtubules Mixed testis: 24.8 -LCMT2 KIAA0547, MGC9534, PPM2, TYW4 ENSG00000168806 Leucine carboxyl methyltransferase 2 15 43323649-43330605 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039401, HPA048176 Approved Approved Nucleoplasm
Vesicles Mixed parathyroid gland: 12.9 -SNTB2 D16S2531E, EST25263, SNT2B2, SNT3, SNTL ENSG00000168807 Syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 16 69187129-69309052 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed parathyroid gland: 34.9 -IL12A CLMF, IL-12A, NFSK, NKSF1, p35 ENSG00000168811 Interleukin 12A 3 159988750-159996019 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA001886 Uncertain Tissue enhanced 0 esophagus: 4.0 fallopian tube: 3.2 -ZNF507 KIAA1084 ENSG00000168813 Zinc finger protein 507 19 32345594-32387667 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030964, HPA049728 Uncertain Supported Nucleoli
Cytosol Expressed in all testis: 34.8 -STX18 Ufe1 ENSG00000168818 Syntaxin 18 4 4415742-4542346 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003019 Approved Approved Plasma membrane Expressed in all cervix: 181.9 -NSG1 ENSG00000168824 Neuron specific gene family member 1 4 4348140-4419058 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035775 Uncertain Approved Mitochondria Tissue enhanced 0 skin: 143.0 cerebral cortex: 68.8 -ZBTB49 FLJ38559, ZNF509 ENSG00000168826 Zinc finger and BTB domain containing 49 4 4290251-4321786 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA024450 Approved Approved Nucleoplasm
Microtubules
Cytosol Mixed testis: 7.3 -GFM1 EFGM, EGF1, GFM ENSG00000168827 G elongation factor, mitochondrial 1 3 158644278-158692575 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034764, HPA034765, HPA061405 Supported Approved Nucleus
Mitochondria Expressed in all parathyroid gland: 64.3 -OR13J1 ENSG00000168828 Olfactory receptor, family 13, subfamily J, member 1 9 35869263-35870601 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected cerebral cortex: 0.3 -HTR1E 5-HT1E ENSG00000168830 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 6 86937306-87016683 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA004931 Approved Tissue enhanced 0 endometrium: 2.4;ovary: 4.9 cerebral cortex: 1.9 -FSTL5 DKFZp566D234, KIAA1263 ENSG00000168843 Follistatin-like 5 4 161383897-162164035 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045909, HPA046724 Uncertain Group enriched 10 adrenal gland: 7.8;cerebral cortex: 16.3 testis: 1.1 -DDX19A DDX19L, FLJ11126 ENSG00000168872 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 16 70346829-70373383 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045252, HPA066668 Approved Uncertain Nucleoplasm Expressed in all parathyroid gland: 50.2 -ATOH8 bHLHa21, FLJ14708, HATH6 ENSG00000168874 Atonal bHLH transcription factor 8 2 85751344-85788066 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA028406 Supported Nucleoplasm Tissue enhanced 0 adipose tissue: 31.6 lung: 17.1 -SOX14 SOX28 ENSG00000168875 SRY (sex determining region Y)-box 14 3 137764284-137766338 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 18 placenta: 2.4;prostate: 1.1 testis: 0.1 -ANKRD49 FGIF, FLJ20189, GBIF ENSG00000168876 Ankyrin repeat domain 49 11 94493629-94499583 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040273, HPA048137 Approved Approved Nucleus
Nucleoli
Golgi apparatus Expressed in all thyroid gland: 25.2 -SFTPB SFTP3, SP-B ENSG00000168878 Surfactant protein B 2 85657314-85668741 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002440, HPA034820, HPA062148 Supported Tissue enriched 911 lung: 5334.1 spleen: 5.8 -USP39 CGI-21, SAD1, SNRNP65 ENSG00000168883 Ubiquitin specific peptidase 39 2 85602856-85649282 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034823 Approved Supported Nucleoplasm Expressed in all placenta: 38.1 -TNIP2 ABIN-2, FLIP1, KLIP, MGC4289 ENSG00000168884 TNFAIP3 interacting protein 2 4 2741648-2756376 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020818, HPA049886, HPA063197 Supported Validated Nucleoplasm
Cytosol Expressed in all appendix: 22.2 -C2orf68 ENSG00000168887 Chromosome 2 open reading frame 68 2 85606654-85612066 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051143 Uncertain Approved Nucleus
Nuclear membrane
Nucleoli
Mitochondria Expressed in all endometrium: 26.2 -TMEM150A FLJ90024, TM6P1, TMEM150 ENSG00000168890 Transmembrane protein 150A 2 85598548-85603196 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA019015 Uncertain Approved Nucleoplasm
Vesicles Mixed placenta: 33.3 -RNF181 HSPC238 ENSG00000168894 Ring finger protein 181 2 85595725-85597613 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046112, HPA062121 Approved Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 171.1 -VAMP5 ENSG00000168899 Vesicle-associated membrane protein 5 2 85584408-85593412 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035082 Supported Approved Nucleoplasm
Plasma membrane Expressed in all lung: 120.0 -BTNL3 BTN9.1, BTNLR ENSG00000168903 Butyrophilin-like 3 5 180988845-181006727 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 25 colon: 25.0;duodenum: 118.3;rectum: 26.8;small intestine: 90.9 gallbladder: 2.5 -LRRC28 FLJ34269, FLJ45242, MGC24976 ENSG00000168904 Leucine rich repeat containing 28 15 99251362-99390729 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039378, HPA040784, HPA066130 Approved Approved Nucleus
Golgi apparatus
Mitochondria Expressed in all testis: 50.0 -MAT2A MATA2, MATII, SAMS2 ENSG00000168906 Methionine adenosyltransferase II, alpha 2 85539165-85545280 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009968, HPA043028 Approved Approved Nucleoplasm
Cytosol Expressed in all thyroid gland: 643.6 -PLA2G4F PLA2G4F/Z ENSG00000168907 Phospholipase A2, group IVF 15 42139034-42156636 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042713, HPA056752 Approved Approved Nucleus
Vesicles Tissue enriched 5 skin: 92.8 lung: 18.4 -ENHO C9orf165, UNQ470 ENSG00000168913 Energy homeostasis associated 9 34521040-34523041 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042575 Approved Tissue enriched 12 cerebral cortex: 140.7 testis: 11.6 -ZNF608 DKFZp434M098, KIAA1281, NY-REN-36 ENSG00000168916 Zinc finger protein 608 5 124636913-124748807 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005545 Approved Approved Nucleoplasm
Cytosol Mixed cerebral cortex: 18.2 -SLC35G2 DKFZp564K2464, MGC3295, TMEM22 ENSG00000168917 Solute carrier family 35, member G2 3 136818647-136855892 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052054, HPA064728 Approved Approved Cytosol Mixed testis: 21.2 -INPP5D hp51CN, SHIP, SHIP1 ENSG00000168918 Inositol polyphosphate-5-phosphatase D 2 233059967-233207903 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016300, HPA070455 Uncertain Approved Cytosol Mixed lymph node: 39.8 -LETM1 ENSG00000168924 Leucine zipper-EF-hand containing transmembrane protein 1 4 1811479-1856247 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011029, HPA011100 Supported Validated Mitochondria Expressed in all cerebral cortex: 16.3 -CTRB1 CTRB ENSG00000168925 Chymotrypsinogen B1 16 75219000-75224924 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 375 pancreas: 48914.0 ovary: 130.3 -CTRB2 ENSG00000168928 Chymotrypsinogen B2 16 75204096-75207185 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 391 pancreas: 29051.6 ovary: 74.2 -TRIM49 RNF18, TRIM49A ENSG00000168930 Tripartite motif containing 49 11 89797655-89808575 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.3 -TMEM129 D4S2561E ENSG00000168936 Transmembrane protein 129, E3 ubiquitin protein ligase 4 1715952-1721358 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060920 Approved Vesicles Expressed in all parathyroid gland: 35.6 -PPIC CYPC ENSG00000168938 Peptidylprolyl isomerase C (cyclophilin C) 5 123023250-123036741 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039163 Approved Mixed thyroid gland: 77.3 -SPRY3 HSPRY3 ENSG00000168939 Sprouty RTK signaling antagonist 3 X 155767812-155782459 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB013505 Uncertain Approved Nucleoli
Cytosol Mixed epididymis: 2.6 -CEP120 CCDC100, FLJ36090 ENSG00000168944 Centrosomal protein 120kDa 5 123344885-123423592 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028823, HPA051556 Uncertain Approved Microtubules
Cytosol Expressed in all testis: 29.6 -STXBP6 amisyn, HSPC156 ENSG00000168952 Syntaxin binding protein 6 (amisyn) 14 24809656-25050297 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003552 Approved Mixed placenta: 60.7 -TM4SF20 FLJ22800, TCCE518 ENSG00000168955 Transmembrane 4 L six family member 20 2 227362156-227381995 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA051838, HPA063184, HPA065531 Uncertain Supported Plasma membrane
Focal adhesion sites Group enriched 36 duodenum: 285.0;small intestine: 167.3 testis: 6.3 -MFF C2orf33, GL004 ENSG00000168958 Mitochondrial fission factor 2 227325151-227357836 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010968, HPA074625 Approved Supported Mitochondria Expressed in all testis: 351.8 -GRM5 GPRC1E, mGlu5, MGLUR5, PPP1R86 ENSG00000168959 Glutamate receptor, metabotropic 5 11 88504576-89065945 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 9 cerebral cortex: 27.3 testis: 3.1 -LGALS9 LGALS9A ENSG00000168961 Lectin, galactoside-binding, soluble, 9 17 27629798-27649560 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046876, HPA047218 Approved Approved Cytosol Mixed rectum: 42.8 -JMJD7-PLA2G4B ENSG00000168970 JMJD7-PLA2G4B readthrough 15 41828095-41848155 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA005726 Uncertain Approved Cytosol Tissue enhanced 0 skin: 37.5 esophagus: 15.7 -CPLX1 CPX-I ENSG00000168993 Complexin 1 4 784957-826198 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071191 Uncertain Vesicles Tissue enriched 11 cerebral cortex: 60.4 adipose tissue: 5.3 -PXDC1 C6orf145 ENSG00000168994 PX domain containing 1 6 3722614-3752026 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA019246 Approved Plasma membrane Mixed placenta: 82.1 -SIGLEC7 CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2 ENSG00000168995 Sialic acid binding Ig-like lectin 7 19 51142299-51153526 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 spleen: 21.3 appendix: 14.8 -NTSR2 NTR2 ENSG00000169006 Neurotensin receptor 2 2 11658178-11670164 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 25 cerebral cortex: 25.1 ovary: 1.0 -E2F6 E2F-6 ENSG00000169016 E2F transcription factor 6 2 11444375-11466177 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065719 Supported Nucleus
Nucleoli Mixed endometrium: 7.1 -FEM1B ENSG00000169018 Fem-1 homolog b (C. elegans) 15 68277803-68295865 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041920, HPA042192 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 105.3 -COMMD8 FLJ20502 ENSG00000169019 COMM domain containing 8 4 47450796-47463719 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035887 Approved Supported Nucleoplasm
Cytosol Expressed in all kidney: 46.0 -ATP5I ENSG00000169020 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E 4 672436-674338 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035010 Supported Validated Mitochondria Expressed in all skeletal muscle: 541.6 -UQCRFS1 RIP1, RIS1, RISP, UQCR5 ENSG00000169021 Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 19 29205321-29213541 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041863, HPA050339 Supported Validated Mitochondria Expressed in all skeletal muscle: 70.9 -MFSD7 FLJ22269, LP2561 ENSG00000169026 Major facilitator superfamily domain containing 7 4 681829-689441 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043593 Uncertain Mixed parathyroid gland: 14.3 -COL4A3 ENSG00000169031 Collagen, type IV, alpha 3 (Goodpasture antigen) 2 227164565-227314792 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042064 Approved Approved Endoplasmic reticulum
Vesicles Tissue enhanced 0 thyroid gland: 26.7 lung: 22.4 -MAP2K1 MAPKK1, MEK1, PRKMK1 ENSG00000169032 Mitogen-activated protein kinase kinase 1 15 66386817-66492312 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003834, HPA026430 Approved Validated Plasma membrane
Cytosol Expressed in all cerebral cortex: 144.8 -KLK7 PRSS6, SCCE ENSG00000169035 Kallikrein-related peptidase 7 19 50976482-50984099 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018994, CAB026342, HPA062126 Supported Supported Plasma membrane Group enriched 5 esophagus: 68.9;skin: 220.0 fallopian tube: 27.6 -HNRNPH1 hnRNPH, HNRPH1 ENSG00000169045 Heterogeneous nuclear ribonucleoprotein H1 (H) 5 179614178-179634784 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000914, HPA001359, HPA016884, CAB032820 Supported Supported Nucleoplasm
Cytosol Expressed in all lymph node: 220.8 -IRS1 HIRS-1 ENSG00000169047 Insulin receptor substrate 1 2 226731317-226799759 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB005261 Approved Approved Nucleoplasm
Cytosol Mixed thyroid gland: 33.8 -MECP2 MRX16, MRX79, RTT ENSG00000169057 Methyl CpG binding protein 2 X 154021573-154137103 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000593, HPA001341, CAB037264 Supported Supported Nucleus Expressed in all parathyroid gland: 29.4 -VCX3A VCX-8r, VCX-A, VCX3 ENSG00000169059 Variable charge, X-linked 3A X 6533618-6535118 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044996, HPA049357 Supported Tissue enriched 207 testis: 27.5 placenta: 0.1 -UPF3A HUPF3A, RENT3A, UPF3 ENSG00000169062 UPF3 regulator of nonsense transcripts homolog A (yeast) 13 114281584-114305817 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018325, HPA061316 Approved Approved Nucleus
Vesicles
Cytosol Expressed in all testis: 84.3 -ZBBX FLJ23049 ENSG00000169064 Zinc finger, B-box domain containing 3 167240287-167381346 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036327, HPA036328 Supported Group enriched 9 fallopian tube: 37.7;testis: 67.4 lung: 5.5 -ACTBL2 DKFZp686D0972 ENSG00000169067 Actin, beta-like 2 5 57480016-57482809 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041264, HPA041271 Uncertain Not detected cervix: 0.3 -ROR2 BDB, BDB1, NTRKR2 ENSG00000169071 Receptor tyrosine kinase-like orphan receptor 2 9 91563091-91950162 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021868 Uncertain Tissue enhanced 0 parathyroid gland: 34.5 endometrium: 21.3 -AR AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1 ENSG00000169083 Androgen receptor X 67544032-67730619 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000001, HPA065701, CAB065764 Supported Approved Mitochondria Mixed fallopian tube: 42.6 -DHRSX DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6 ENSG00000169084 Dehydrogenase/reductase (SDR family) X-linked X 2219516-2502805 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA003035 Approved Approved Actin filaments
Cytosol Expressed in all thyroid gland: 17.0 -C8orf46 MGC33510 ENSG00000169085 Chromosome 8 open reading frame 46 8 66460003-66518524 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA075134 Approved Nuclear speckles Tissue enriched 15 cerebral cortex: 65.3 seminal vesicle: 4.4 -HSPBAP1 FLJ22623, PASS1 ENSG00000169087 HSPB (heat shock 27kDa) associated protein 1 3 122740003-122793824 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044930 Approved Approved Mitochondria Mixed testis: 19.2 -ASMTL ENSG00000169093 Acetylserotonin O-methyltransferase-like X 1403139-1453762 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003630, HPA021865 Supported Validated Cytosol Expressed in all seminal vesicle: 36.1 -SLC25A6 ANT3, ANT3Y, MGC17525 ENSG00000169100 Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 X 1386152-1392724 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046835, HPA071684 Approved Supported Mitochondria Expressed in all duodenum: 294.5 -CHST14 D4ST-1, D4ST1, HD4ST ENSG00000169105 Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 15 40470998-40474571 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057697, HPA071601 Approved Approved Vesicles Expressed in all placenta: 38.5 -PARM1 Cipar1, DKFZP564O0823, WSC4 ENSG00000169116 Prostate androgen-regulated mucin-like protein 1 4 74933095-75050115 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038236 Approved Approved Nucleus
Vesicles
Cytosol Mixed thyroid gland: 205.6 -CSNK1G1 CK1gamma1 ENSG00000169118 Casein kinase 1, gamma 1 15 64165517-64356259 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018209 Supported Cytosol Tissue enhanced 0 testis: 63.5 thyroid gland: 14.1 -FAM110B C8orf72, MGC39325 ENSG00000169122 Family with sequence similarity 110, member B 8 57994509-58204279 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008318, HPA011781 Uncertain Supported Mitochondria
Cytosol Tissue enhanced 0 spleen: 28.6 cerebral cortex: 17.7 -ARMC4 CILD23, DKFZP434P1735, FLJ10376, FLJ10817 ENSG00000169126 Armadillo repeat containing 4 10 27812164-27999048 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037829 Approved Group enriched 10 fallopian tube: 28.5;testis: 41.6 prostate: 3.3 -AFAP1L2 Em:AC005383.4, FLJ14564, KIAA1914, XB130 ENSG00000169129 Actin filament associated protein 1-like 2 10 114294824-114404756 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037843 Approved Supported Plasma membrane
Cytosol Tissue enhanced 0 thyroid gland: 137.4 parathyroid gland: 92.9 -ZNF354A EZNF, HKL1, KID-1, KID1, TCF17 ENSG00000169131 Zinc finger protein 354A 5 178711592-178730702 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA052043 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all testis: 16.7 -ATF5 ENSG00000169136 Activating transcription factor 5 19 49928702-49933935 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA030187 Uncertain Supported Nucleoplasm
Cytosol Group enriched 7 liver: 387.7;thyroid gland: 190.1 appendix: 43.6 -UBE2V2 DDVit-1, EDPF-1, MMS2, UEV-2 ENSG00000169139 Ubiquitin-conjugating enzyme E2 variant 2 8 48008400-48064708 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052535, HPA053186 Supported Nucleoplasm Expressed in all cerebral cortex: 97.9 -GOT1L1 MGC33309 ENSG00000169154 Glutamic-oxaloacetic transaminase 1-like 1 8 37934281-37940129 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028778 Uncertain Tissue enriched 26 testis: 21.3 ovary: 0.8 -ZBTB43 FLJ22470, KIAA0414, ZBTB22B, ZNF-X, ZNF297B ENSG00000169155 Zinc finger and BTB domain containing 43 9 126805006-126838210 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016825 Approved Approved Nucleus
Nucleoli Expressed in all bone marrow: 38.8 -CPT1C CPT1P, CPTIC, FLJ23809 ENSG00000169169 Carnitine palmitoyltransferase 1C 19 49690898-49713731 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014529 Supported Approved Centrosome Tissue enhanced 0 cerebral cortex: 34.3 adrenal gland: 7.0 -PCSK9 FH3, HCHOLA3, NARC-1 ENSG00000169174 Proprotein convertase subtilisin/kexin type 9 1 55039548-55064852 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 liver: 6.1;lung: 11.1 colon: 3.5 -XPO6 FLJ22519, KIAA0370, RANBP20 ENSG00000169180 Exportin 6 16 28097979-28211920 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038246 Uncertain Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Expressed in all testis: 94.0 -GSG1L KTSR5831, MGC18079, PRO19651 ENSG00000169181 GSG1-like 16 27787535-28063509 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA014479 Approved Tissue enhanced 0 cerebral cortex: 11.7;heart muscle: 8.8 fallopian tube: 2.7 -MN1 MGCR, MGCR1, MGCR1-PEN ENSG00000169184 Meningioma (disrupted in balanced translocation) 1 22 27748277-27801498 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003072 Approved Approved Nucleoplasm Tissue enhanced 0 skeletal muscle: 22.0 cerebral cortex: 6.4 -APEX2 APE2, APEXL2, XTH2, ZGRF2 ENSG00000169188 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 X 55000357-55009057 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048577 Supported Nucleus
Nucleoli fibrillar center
Vesicles Expressed in all skin: 14.3 -NSMCE1 NSE1 ENSG00000169189 NSE1 homolog, SMC5-SMC6 complex component 16 27224991-27268794 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041567, HPA043091 Supported Supported Nucleoplasm
Vesicles Expressed in all parathyroid gland: 121.1 -CCDC126 FLJ23031 ENSG00000169193 Coiled-coil domain containing 126 7 23597379-23644708 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026883 Uncertain Approved Nucleoplasm Expressed in all testis: 61.6 -IL13 ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600 ENSG00000169194 Interleukin 13 5 132656263-132661110 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042421 Approved Plasma membrane
Cytosol Tissue enriched 10 testis: 19.9 gallbladder: 2.0 -RP11-231C14.4 ENSG00000169203 16 29483642-29505999 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level HPA053611 Approved Uncertain Nucleoplasm Expressed in all skin: 135.7 -OR10G3 ENSG00000169208 Olfactory receptor, family 10, subfamily G, member 3 14 21569803-21570744 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA019766 Uncertain Not detected adipose tissue: 0.0 -RAB3B ENSG00000169213 RAB3B, member RAS oncogene family 1 51907956-51990764 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003159, CAB023293 Supported Tissue enhanced 0 cerebral cortex: 8.2;prostate: 18.0 adrenal gland: 4.1 -OR6F1 OST731 ENSG00000169214 Olfactory receptor, family 6, subfamily F, member 1 1 247711829-247712755 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 22 testis: 2.2 adipose tissue: 0.0 -CD2BP2 LIN1, PPP1R59, Snu40 ENSG00000169217 CD2 (cytoplasmic tail) binding protein 2 16 30350766-30355361 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041508, HPA061309 Supported Validated Nuclear speckles
Cytosol Expressed in all parathyroid gland: 79.8 -RSPO1 FLJ40906, RSPONDIN ENSG00000169218 R-spondin 1 1 37611350-37634923 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046154 Uncertain Tissue enhanced 0 endometrium: 43.3;fallopian tube: 32.8 smooth muscle: 21.0 -RGS14 ENSG00000169220 Regulator of G-protein signaling 14 5 177357837-177372601 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046847, HPA061819 Approved Validated Nucleoplasm
Vesicles Mixed spleen: 22.1 -TBC1D10B DKFZP434P1750, EPI64B, FLJ13130, Rab27A-GAPbeta ENSG00000169221 TBC1 domain family, member 10B 16 30357102-30370264 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048894 Uncertain Expressed in all testis: 36.0 -LMAN2 C5orf8, GP36B, VIP36 ENSG00000169223 Lectin, mannose-binding 2 5 177331562-177351852 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003927 Approved Expressed in all epididymis: 162.0 -GCSAML C1orf150, FLJ44728 ENSG00000169224 Germinal center-associated, signaling and motility-like 1 247507058-247577690 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027507, HPA027510 Uncertain Approved Cytosol Tissue enhanced 0 prostate: 8.4;testis: 7.7 lung: 3.4 -RAB24 ENSG00000169228 RAB24, member RAS oncogene family 5 177301198-177303744 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034945 Uncertain Focal adhesion sites Expressed in all spleen: 40.8 -PRELID1 CGI-106, PRELI, PX19 ENSG00000169230 PRELI domain containing 1 5 177303774-177306959 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005701 Approved Supported Nucleoplasm
Mitochondria Expressed in all small intestine: 133.0 -THBS3 ENSG00000169231 Thrombospondin 3 1 155195588-155209051 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006293 Approved Expressed in all smooth muscle: 41.6 -CA5B ENSG00000169239 Carbonic anhydrase VB, mitochondrial X 15688830-15788409 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012618 Uncertain Supported Mitochondria Mixed cervix: 34.0 -SLC50A1 HsSWEET1, RAG1AP1, RP11-540D14.5, RZPDo834D038D, SCP, slv, SWEET1 ENSG00000169241 Solute carrier family 50 (sugar efflux transporter), member 1 1 155135344-155138857 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA018095 Approved Expressed in all epididymis: 133.2 -EFNA1 ECKLG, EPLG1, LERK1, TNFAIP4 ENSG00000169242 Ephrin-A1 1 155127460-155134857 Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB032498 Uncertain Mixed placenta: 123.0 -CXCL10 C7, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10 ENSG00000169245 Chemokine (C-X-C motif) ligand 10 4 76021117-76023497 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 133.1 lymph node: 73.6 -NPIPB3 KIAA0220, NPIPL3 ENSG00000169246 Nuclear pore complex interacting protein family, member B3 16 21402237-21448567 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA053611 Approved Approved Nucleoplasm Expressed in all skin: 229.8 -SH3TC2 CMT4C, KIAA1985 ENSG00000169247 SH3 domain and tetratricopeptide repeats 2 5 148923639-149063163 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037683, HPA037684 Uncertain Approved Nucleoplasm
Cytosol Group enriched 6 cerebral cortex: 3.0;placenta: 2.8;testis: 8.7 heart muscle: 0.8 -CXCL11 b-R1, H174, I-TAC, IP-9, SCYB11, SCYB9B ENSG00000169248 Chemokine (C-X-C motif) ligand 11 4 76033682-76041415 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB009921 Uncertain Tissue enhanced 0 appendix: 14.0 lymph node: 11.7 -ZRSR2 U2AF1-RS2, U2AF1L2, URP, ZC3H22 ENSG00000169249 Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 X 15790472-15823260 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all spleen: 34.8 -NMD3 CGI-07 ENSG00000169251 NMD3 ribosome export adaptor 3 161104696-161253532 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035019 Supported Nucleus
Nucleoli Expressed in all prostate: 43.8 -ADRB2 ADRB2R, ADRBR, B2AR, BAR ENSG00000169252 Adrenoceptor beta 2, surface 5 148825245-148828687 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003431, HPA075322 Uncertain Uncertain Cytosol Mixed lung: 16.3 -B3GALNT1 B3GALT3, beta3Gal-T3, galT3, GLOB, P1 ENSG00000169255 Beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 3 161083883-161105384 Blood group antigen proteins, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041204 Approved Vesicles Mixed thyroid gland: 47.6 -GPRIN1 GRIN1, KIAA1893 ENSG00000169258 G protein regulated inducer of neurite outgrowth 1 5 176595802-176610133 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036478, HPA070892 Supported Supported Vesicles
Plasma membrane Tissue enriched 7 cerebral cortex: 27.9 duodenum: 3.9 -HSPB3 HSPL27 ENSG00000169271 Heat shock 27kDa protein 3 5 54455601-54456384 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062124 Supported Nuclear speckles Group enriched 10 heart muscle: 224.5;skeletal muscle: 64.3 esophagus: 14.1 -KCNAB1 AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3 ENSG00000169282 Potassium channel, voltage gated subfamily A regulatory beta subunit 1 3 156037701-156539138 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044550 Approved Tissue enhanced 0 thyroid gland: 48.3 prostate: 37.6 -MRPL1 BM022 ENSG00000169288 Mitochondrial ribosomal protein L1 4 77862520-77952790 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043656 Supported Supported Mitochondria Expressed in all kidney: 29.3 -SHE ENSG00000169291 Src homology 2 domain containing E 1 154469772-154502113 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037417 Approved Mixed testis: 31.9 -NR0B1 AHC, AHCH, DAX1, DSS, NR0B1 ENSG00000169297 Nuclear receptor subfamily 0, group B, member 1 X 30304206-30309598 Cancer-related genes, Disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070839 Supported Nucleoplasm Group enriched 7 adrenal gland: 27.9;testis: 34.9 ovary: 4.2 -PGM2 FLJ10983 ENSG00000169299 Phosphoglucomutase 2 4 37826633-37862937 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040676 Uncertain Approved Intermediate filaments Mixed esophagus: 36.6 -STK32A MGC22688, YANK1 ENSG00000169302 Serine/threonine kinase 32A 5 147234963-147387852 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040236 Uncertain Approved Centrosome Tissue enhanced 0 adrenal gland: 15.7;thyroid gland: 16.1 cerebral cortex: 7.4 -IL1RAPL1 IL1R8, IL1RAPL, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2 ENSG00000169306 Interleukin 1 receptor accessory protein-like 1 X 28587399-29956723 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 12 cerebral cortex: 5.1 seminal vesicle: 0.4 -P2RY12 HORK3, P2Y12, SP1999 ENSG00000169313 Purinergic receptor P2Y, G-protein coupled, 12 3 151337380-151384812 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013796, HPA014518 Supported Tissue enriched 6 cerebral cortex: 84.0 lymph node: 13.3 -C22orf15 FLJ36561, N27C7-3 ENSG00000169314 Chromosome 22 open reading frame 15 22 23763021-23765861 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018006, HPA019494 Uncertain Tissue enriched 15 fallopian tube: 29.0 testis: 1.9 -OR5AU1 ENSG00000169327 Olfactory receptor, family 5, subfamily AU, member 1 14 21154865-21156063 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected seminal vesicle: 0.2 -KIAA1024 ENSG00000169330 KIAA1024 15 79432516-79472290 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA011545 Uncertain Approved Golgi apparatus Tissue enriched 11 adrenal gland: 14.0 salivary gland: 1.2 -PDILT PDIA7 ENSG00000169340 Protein disulfide isomerase-like, testis expressed 16 20359170-20404737 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041913 Approved Tissue enriched 5 testis: 31.3 stomach: 5.9 -UMOD ENSG00000169344 Uromodulin 16 20333052-20356301 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009446, HPA043420, HPA054721 Supported Tissue enriched 718 kidney: 2377.1 cerebral cortex: 3.3 -GP2 ENSG00000169347 Glycoprotein 2 (zymogen granule membrane) 16 20309572-20327808 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA015739, HPA016668 Supported Tissue enriched 200 pancreas: 7528.0 duodenum: 37.5 -SLC33A1 ACATN, AT-1, AT1, SPG42 ENSG00000169359 Solute carrier family 33 (acetyl-CoA transporter), member 1 3 155821024-155854429 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042430 Uncertain Expressed in all thyroid gland: 67.1 -SNUPN RNUT1, SNURPORTIN-1, Snurportin1 ENSG00000169371 Snurportin 1 15 75598083-75626469 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005004 Approved Supported Nuclear membrane Expressed in all testis: 54.0 -CRADD RAIDD ENSG00000169372 CASP2 and RIPK1 domain containing adaptor with death domain 12 93677375-93894840 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB005337 Uncertain Approved Nucleus
Cytosol Expressed in all parathyroid gland: 32.2 -SIN3A DKFZP434K2235, KIAA0700 ENSG00000169375 SIN3 transcription regulator family member A 15 75369379-75455842 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004506, HPA047213, HPA062123 Supported Validated Nucleoplasm Expressed in all testis: 55.4 -ARL13B ARL2L1, DKFZp761H079, JBTS8 ENSG00000169379 ADP-ribosylation factor-like 13B 3 93980139-94055668 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048926 Approved Uncertain Microtubules
Cytosol Mixed thyroid gland: 9.4 -RNASE2 EDN, RAF3, RNS2 ENSG00000169385 Ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 14 20955452-20956436 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044983 Supported Tissue enriched 74 bone marrow: 998.6 smooth muscle: 13.4 -ELSPBP1 E12, EDDM12, HE12 ENSG00000169393 Epididymal sperm binding protein 1 19 47994651-48025153 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044256, HPA050341 Supported Tissue enriched 2020 epididymis: 3575.4 testis: 1.7 -RNASE3 ECP, RAF1, RNS3 ENSG00000169397 Ribonuclease, RNase A family, 3 14 20891399-20892348 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056183 Supported Tissue enriched 300 bone marrow: 573.6 skin: 1.9 -PTK2 FADK, FAK, FAK1, PPP1R71 ENSG00000169398 Protein tyrosine kinase 2 8 140657900-141002216 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001842, CAB004036, HPA029671 Approved Supported Vesicles
Focal adhesion sites
Cytosol Expressed in all placenta: 106.5 -RSPH10B2 ENSG00000169402 Radial spoke head 10 homolog B2 (Chlamydomonas) 7 6754109-6799365 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047076, HPA049181, HPA049182 Uncertain Group enriched 7 fallopian tube: 16.2;testis: 35.7 parathyroid gland: 3.8 -PTAFR ENSG00000169403 Platelet-activating factor receptor 1 28147166-28193936 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027543 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Tissue enhanced 0 appendix: 42.1 bone marrow: 26.2 -PTPN9 MEG2 ENSG00000169410 Protein tyrosine phosphatase, non-receptor type 9 15 75463251-75579289 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041922 Approved Approved Vesicles Expressed in all thyroid gland: 54.6 -RNASE6 RAD1, RNS6 ENSG00000169413 Ribonuclease, RNase A family, k6 14 20781051-20782467 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000698 Approved Mixed lymph node: 91.6 -NPR1 ANPa, ANPRA, GUCY2A, NPRA ENSG00000169418 Natriuretic peptide receptor 1 1 153678637-153693992 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031087 Approved Nucleus
Nucleoli
Plasma membrane Tissue enhanced 0 adipose tissue: 71.8;fallopian tube: 57.6 placenta: 25.2 -KCNK9 K2p9.1, TASK-3, TASK3 ENSG00000169427 Potassium channel, two pore domain subfamily K, member 9 8 139600838-139703056 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 7 adrenal gland: 4.8;cerebral cortex: 4.8 cervix: 0.7 -CXCL8 3-10C, AMCF-I, b-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1 ENSG00000169429 Chemokine (C-X-C motif) ligand 8 4 73740506-73743716 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA057179 Supported Approved Golgi apparatus Tissue enriched 7 bone marrow: 2079.8 appendix: 297.8 -SCN9A ETHA, Nav1.7, NE-NA, NENA, PN1 ENSG00000169432 Sodium channel, voltage gated, type IX alpha subunit 2 166195185-166375993 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013679, HPA061843 Uncertain Approved Plasma membrane
Actin filaments
Focal adhesion sites Tissue enhanced 0 testis: 9.1 placenta: 5.9 -RASSF6 ENSG00000169435 Ras association (RalGDS/AF-6) domain family member 6 4 73571550-73620631 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA037712 Approved Approved Nucleoplasm
Golgi apparatus Tissue enhanced 0 stomach: 32.9 rectum: 14.0 -COL22A1 ENSG00000169436 Collagen, type XXII, alpha 1 8 138588235-138914006 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024830 Approved Supported Endoplasmic reticulum
Vesicles Tissue enhanced 0 adrenal gland: 9.8 prostate: 4.8 -SDC2 CD362, fibroglycan, HSPG, HSPG1, SYND2 ENSG00000169439 Syndecan 2 8 96493351-96611780 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025123, HPA044416 Uncertain Approved Plasma membrane
Cytosol Expressed in all thyroid gland: 708.5 -CD52 CDW52 ENSG00000169442 CD52 molecule 1 26317957-26320523 Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 34 epididymis: 43067.6 lymph node: 1271.7 -MMGT1 EMC5, TMEM32 ENSG00000169446 Membrane magnesium transporter 1 X 135962070-135974063 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032037 Approved Expressed in all thyroid gland: 34.4 -SPRR1B GADD33, SPRR1 ENSG00000169469 Small proline-rich protein 1B 1 153031202-153032900 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 esophagus: 2466.0 tonsil: 422.7 -SPRR1A ENSG00000169474 Small proline-rich protein 1A 1 152985231-152985500 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011237 Supported Tissue enriched 12 esophagus: 9986.0 tonsil: 858.5 -OR4K14 ENSG00000169484 Olfactory receptor, family 4, subfamily K, member 14 14 20014260-20015193 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -OR4K15 OR4K15Q ENSG00000169488 Olfactory receptor, family 4, subfamily K, member 15 14 19975444-19976659 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA055732 Uncertain Not detected epididymis: 0.0 -TM2D2 BLP1 ENSG00000169490 TM2 domain containing 2 8 38988808-38996824 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047152, HPA050547 Approved Approved Nucleoplasm
Vesicles
Plasma membrane Expressed in all testis: 51.1 -HTRA4 FLJ90724 ENSG00000169495 HtrA serine peptidase 4 8 38974164-38988662 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045402 Approved Tissue enriched 20 placenta: 94.4 bone marrow: 4.8 -PLEKHA2 TAPP2 ENSG00000169499 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 8 38901235-38973909 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA004706 Approved Uncertain Nucleus
Nuclear bodies
Cytosol Expressed in all lymph node: 92.9 -CLIC4 CLIC4L, DKFZP566G223, H1, huH1, P64H1 ENSG00000169504 Chloride intracellular channel 4 1 24745357-24844324 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008019, HPA060804 Supported Supported Cytosol Expressed in all smooth muscle: 393.9 -SLC38A11 AVT2, FLJ39822 ENSG00000169507 Solute carrier family 38, member 11 2 164896186-164955525 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043432 Uncertain Tissue enhanced 0 epididymis: 47.1;gallbladder: 28.3 seminal vesicle: 23.3 -GPR183 EBI2 ENSG00000169508 G protein-coupled receptor 183 13 99294530-99307405 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028847, CAB033690 Uncertain Approved Nuclear membrane
Vesicles Mixed appendix: 117.8 -CRCT1 C1orf42, NICE-1 ENSG00000169509 Cysteine-rich C-terminal 1 1 152514502-152516010 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 11 esophagus: 84.4;skin: 82.8;tonsil: 18.4 breast: 5.6 -CCDC8 3M3, DKFZp564K0322, PPP1R20 ENSG00000169515 Coiled-coil domain containing 8 19 46410372-46413584 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041993 Uncertain Approved Nucleus
Plasma membrane
Cytosol Tissue enhanced 0 ovary: 45.4 fallopian tube: 37.4 -METTL15 FLJ33979, METT5D1 ENSG00000169519 Methyltransferase like 15 11 28108248-28527041 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039885 Approved Golgi apparatus
Plasma membrane
Actin filaments Mixed parathyroid gland: 14.4 -ZNF280A 3'OY11.1, SUHW1, ZNF280, ZNF636 ENSG00000169548 Zinc finger protein 280A 22 22513736-22520270 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044475 Uncertain Uncertain Nucleoplasm Not detected adrenal gland: 0.3 -MUC15 ENSG00000169550 Mucin 15, cell surface associated 11 26559033-26572233 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026110 Approved Tissue enriched 18 epididymis: 2780.4 thyroid gland: 158.6 -CT55 CXorf48, FLJ20527 ENSG00000169551 Cancer/testis antigen 55 X 135156536-135171398 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 31 testis: 6.5 cerebral cortex: 0.2 -ZEB2 KIAA0569, SIP-1, SIP1, ZFHX1B ENSG00000169554 Zinc finger E-box binding homeobox 2 2 144384081-144524583 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003456 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all cerebral cortex: 95.9 -GJB1 CMTX, CMTX1, CX32 ENSG00000169562 Gap junction protein, beta 1, 32kDa X 71215194-71225516 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB012994 Uncertain Tissue enhanced 0 liver: 159.3 gallbladder: 59.5 -PCBP1 hnRNP-E1, hnRNP-X, HNRPE1, HNRPX ENSG00000169564 Poly(rC) binding protein 1 2 70087454-70089203 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037113, HPA043803, HPA068497 Supported Validated Nuclear speckles
Cytoplasmic bodies Expressed in all spleen: 288.8 -HINT1 HINT, PKCI-1, PRKCNH1 ENSG00000169567 Histidine triad nucleotide binding protein 1 5 131159027-131171735 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044577 Approved Supported Nucleus
Plasma membrane
Cytosol Expressed in all cerebral cortex: 174.4 -DTWD2 FLJ33977 ENSG00000169570 DTW domain containing 2 5 118837322-118988545 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053173, HPA054864 Approved Supported Nuclear bodies Mixed thyroid gland: 18.6 -VPREB1 CD179A, VpreB ENSG00000169575 Pre-B lymphocyte 1 22 22244675-22245515 CD markers, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055886 Uncertain Tissue enriched 15 bone marrow: 17.1 tonsil: 1.1 -CLIC3 ENSG00000169583 Chloride intracellular channel 3 9 136994635-136996803 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005963 Approved Supported Nuclear bodies Tissue enhanced 0 esophagus: 87.1;thyroid gland: 85.5 skin: 43.6 -INO80E CCDC95, FLJ90652 ENSG00000169592 INO80 complex subunit E 16 29995294-30005793 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043146 Approved Supported Nucleoplasm
Nucleoli Expressed in all fallopian tube: 62.8 -BNC1 BNC, HsT19447 ENSG00000169594 Basonuclin 1 15 83255903-83284716 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063183, HPA066947 Approved Nucleoplasm Tissue enhanced 0 testis: 55.7 esophagus: 11.9 -DFFB CAD, CPAN, DFF-40, DFF40 ENSG00000169598 DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 1 3857267-3885429 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004328, HPA052904 Approved Approved Nucleus
Nucleoli Mixed duodenum: 2.9 -NFU1 CGI-33, HIRIP5, NifU, NIFUC ENSG00000169599 NFU1 iron-sulfur cluster scaffold 2 69395750-69437628 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035826 Uncertain Supported Nucleoplasm
Cytosol Expressed in all adipose tissue: 71.1 -ANTXR1 ATR, FLJ10601, FLJ21776, TEM8 ENSG00000169604 Anthrax toxin receptor 1 2 69013178-69249327 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052046, HPA054785 Uncertain Uncertain Vesicles Mixed gallbladder: 180.9 -GKN1 AMP18, BRICD1, CA11 ENSG00000169605 Gastrokine 1 2 68974573-68980974 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047684 Supported Tissue enriched 1194 stomach: 31692.5 placenta: 26.5 -CKAP2L FLJ40629, radmis ENSG00000169607 Cytoskeleton associated protein 2-like 2 112736607-112764677 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039407, HPA040057, HPA070737 Uncertain Supported Mitotic spindle
Cytosol Tissue enhanced 0 bone marrow: 8.8;testis: 9.9 lymph node: 6.4 -C15orf40 MGC29937 ENSG00000169609 Chromosome 15 open reading frame 40 15 82988441-83011641 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042980 Approved Approved Nucleus
Cytosol Expressed in all epididymis: 26.7 -FAM103A1 C15orf18, HsT19360, MGC2560, RAM ENSG00000169612 Family with sequence similarity 103, member A1 15 82986207-82991057 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041923, HPA041948 Supported Supported Nucleoplasm Expressed in all epididymis: 38.1 -PROKR1 GPR73, GPR73a, PKR1, ZAQ ENSG00000169618 Prokineticin receptor 1 2 68643589-68658247 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029396 Uncertain Group enriched 8 adipose tissue: 1.7;adrenal gland: 1.4;epididymis: 4.3 testis: 0.3 -APLF C2orf13, MGC47799, Xip1, ZCCHH1 ENSG00000169621 Aprataxin and PNKP like factor 2 68467561-68655862 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029396, HPA034642, HPA034643 Approved Supported Nucleoplasm Mixed skin: 3.3 -BOLA2B ENSG00000169627 BolA family member 2B 16 30192934-30194306 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045380, HPA046696 Supported Uncertain Nucleus Expressed in all lymph node: 33.1 -RGPD8 RanBP2alpha, RANBP2L1 ENSG00000169629 RANBP2-like and GRIP domain containing 8 2 112370092-112434488 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045704, HPA049497, HPA051675, HPA067564 Uncertain Uncertain Nuclear membrane
Vesicles Tissue enriched 5 testis: 31.6 cerebral cortex: 5.8 -HIC2 HRG22, KIAA1020, ZBTB30, ZNF907 ENSG00000169635 Hypermethylated in cancer 2 22 21417404-21451463 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031884, HPA059399 Uncertain Supported Nucleus Mixed placenta: 8.4 -LUZP1 LUZP ENSG00000169641 Leucine zipper protein 1 1 23084023-23177808 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028506, HPA028542 Supported Uncertain Vesicles
Actin filaments
Cytosol Expressed in all parathyroid gland: 46.2 -HEXDC FLJ23825 ENSG00000169660 Hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 17 82418318-82442645 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA022834, HPA023379, HPA027844 Uncertain Approved Nucleoli fibrillar center
Mitochondria Expressed in all spleen: 25.9 -DRD5 DRD1B, DRD1L2 ENSG00000169676 Dopamine receptor D5 4 9781680-9784009 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA048930 Supported Tissue enhanced 0 appendix: 1.8;cerebral cortex: 2.0;stomach: 3.7 testis: 0.8 -BUB1 BUB1A, BUB1L, hBUB1 ENSG00000169679 BUB1 mitotic checkpoint serine/threonine kinase 2 110637698-110678114 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006123 Supported Nucleoplasm
Cytosol Tissue enhanced 0 testis: 69.2 lymph node: 24.3 -SPNS1 HSpin1, LAT, nrs, PP2030, SPIN1, SPINL ENSG00000169682 Spinster homolog 1 (Drosophila) 16 28974221-28984548 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041995, HPA042988 Supported Approved Nucleoli fibrillar center
Golgi apparatus
Vesicles
Cytosol Expressed in all parathyroid gland: 36.3 -LRRC45 MGC20806 ENSG00000169683 Leucine rich repeat containing 45 17 82023302-82031151 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023372, HPA023382, HPA024768 Supported Supported Nucleoplasm
Plasma membrane
Centrosome
Cytosol Mixed fallopian tube: 8.2 -CHRNA5 ENSG00000169684 Cholinergic receptor, nicotinic, alpha 5 (neuronal) 15 78565520-78595269 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054381 Approved Approved Plasma membrane
Focal adhesion sites Mixed gallbladder: 6.9 -MT1B MT1, MT1Q ENSG00000169688 Metallothionein 1B 16 56651899-56653204 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enhanced 0 duodenum: 1.3;liver: 3.2 appendix: 0.5 -STRA13 FAAP10, MGC14480, MHF2 ENSG00000169689 Stimulated by retinoic acid 13 17 82018702-82024107 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all prostate: 67.4 -AGPAT2 BSCL, LPAAT-beta ENSG00000169692 1-acylglycerol-3-phosphate O-acyltransferase 2 9 136673143-136687423 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019544 Uncertain Approved Centrosome Expressed in all adipose tissue: 299.8 -ASPSCR1 ASPL, ASPS, UBXD9, UBXN9 ENSG00000169696 Alveolar soft part sarcoma chromosome region, candidate 1 17 81976807-82017406 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026749 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Expressed in all testis: 21.3 -GP9 CD42a, GPIX ENSG00000169704 Glycoprotein IX (platelet) 3 129060767-129062406 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063182 Supported Tissue enhanced 0 bone marrow: 2.9;spleen: 2.8 testis: 1.2 -FASN FAS, SDR27X1 ENSG00000169710 Fatty acid synthase 17 82078333-82098332 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005192, HPA006461, CAB015417, HPA056108 Supported Validated Plasma membrane
Cytosol Expressed in all adipose tissue: 283.6 -CNBP CNBP1, DM2, RNF163, ZCCHC22, ZNF9 ENSG00000169714 CCHC-type zinc finger, nucleic acid binding protein 3 129169484-129183922 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063097 Supported Nucleus
Cytosol Expressed in all ovary: 473.3 -MT1E MT1, MTD ENSG00000169715 Metallothionein 1E 16 56625475-56627112 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 418.9 -ACTRT2 Arp-T2, ARPM2, FLJ25424 ENSG00000169717 Actin-related protein T2 1 3021483-3022903 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA006480, HPA025079 Supported Tissue enriched 1023 testis: 102.2 adipose tissue: 0.0 -DUS1L DUS1, PP3111 ENSG00000169718 Dihydrouridine synthase 1-like 17 82057506-82065887 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023384 Uncertain Approved Plasma membrane Expressed in all skin: 99.1 -GPS1 COPS1, CSN1 ENSG00000169727 G protein pathway suppressor 1 17 82050691-82057470 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 77.1 -RFNG ENSG00000169733 RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 17 82047902-82051831 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011564, HPA031673 Uncertain Supported Nucleus Expressed in all fallopian tube: 19.4 -DCXR DCR, KIDCR, SDR20C1 ENSG00000169738 Dicarbonyl/L-xylulose reductase 17 82035136-82037732 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023371, HPA023863 Supported Uncertain Nucleoli
Microtubules Group enriched 6 epididymis: 292.3;kidney: 216.4;liver: 638.6;prostate: 134.3 adipose tissue: 56.5 -ZNF32 KOX30 ENSG00000169740 Zinc finger protein 32 10 43643859-43648856 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA039148, HPA059640 Supported Nucleoplasm
Nuclear bodies Expressed in all epididymis: 70.7 -LDB2 CLIM1, LDB1 ENSG00000169744 LIM domain binding 2 4 16501541-16898809 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017544, HPA068634 Supported Supported Nucleus
Nucleoli Mixed endometrium: 107.5 -RAC3 ENSG00000169750 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 17 82031624-82034204 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047820 Uncertain Mixed testis: 22.8 -NRG4 HRG4 ENSG00000169752 Neuregulin 4 15 75935969-76059795 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA010957 Uncertain Tissue enhanced 0 fallopian tube: 1.0;testis: 1.3 stomach: 0.9 -LIMS1 PINCH, PINCH1 ENSG00000169756 LIM and senescent cell antigen-like domains 1 2 108534355-108687246 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058455, HPA061230 Approved Supported Focal adhesion sites
Cytosol Expressed in all adrenal gland: 59.7 -TMEM266 C15orf27, FLJ38190 ENSG00000169758 Transmembrane protein 266 15 76059837-76229121 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA041921 Uncertain Supported Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 1.9;skeletal muscle: 1.5 placenta: 1.1 -NLGN1 KIAA1070 ENSG00000169760 Neuroligin 1 3 173396284-174286644 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006572, HPA006680 Approved Uncertain Nuclear bodies
Plasma membrane Tissue enhanced 0 cerebral cortex: 25.5 testis: 12.5 -TAPT1 FLJ90013 ENSG00000169762 Transmembrane anterior posterior transformation 1 4 16160505-16227410 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042567, HPA048658 Approved Approved Vesicles Expressed in all cerebral cortex: 21.6 -UGP2 UGP1, UGPP1 ENSG00000169764 UDP-glucose pyrophosphorylase 2 2 63840940-63891562 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034696, HPA034697, HPA064836 Supported Approved Nucleoplasm
Centrosome
Mitochondria Expressed in all liver: 450.1 -TAS2R1 T2R1, TRB7 ENSG00000169777 Taste receptor, type 2, member 1 5 9628997-9712378 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051879 Uncertain Tissue enriched 41 testis: 13.2 fallopian tube: 0.3 -LINGO1 FLJ14594, LERN1, LRRN6A ENSG00000169783 Leucine rich repeat and Ig domain containing 1 15 77613027-77820900 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA074653 Approved Plasma membrane Tissue enriched 13 cerebral cortex: 131.2 heart muscle: 9.7 -PRY PRY1, PTPN13LY ENSG00000169789 PTPN13-like, Y-linked Y 22490397-22514637 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA046366 Uncertain Not detected epididymis: 0.2 -RBMY1F MGC33094 ENSG00000169800 RNA binding motif protein, Y-linked, family 1, member F Y 22168542-22182982 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA001534, HPA053147 Supported Not detected adipose tissue: 0.0 -PRY2 PTPN13LY2 ENSG00000169807 PTPN13-like, Y-linked 2 Y 22071756-22096007 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA046366 Uncertain Not detected testis: 0.1 -HNRNPF HNRPF ENSG00000169813 Heterogeneous nuclear ribonucleoprotein F 10 43385617-43409166 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016884, HPA069667 Supported Validated Nucleoplasm Expressed in all lymph node: 195.4 -BTD ENSG00000169814 Biotinidase 3 15601341-15645822 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052275 Uncertain Expressed in all epididymis: 52.1 -CSGALNACT2 GALNACT-2, GALNACT2, MGC40204, PRO0082 ENSG00000169826 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 10 43138486-43185308 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031540 Approved Approved Endoplasmic reticulum Expressed in all bone marrow: 87.4 -TACR3 NK3R ENSG00000169836 Tachykinin receptor 3 4 103586031-103719816 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA009418 Uncertain Not detected cerebral cortex: 0.5 -GSX1 Gsh-1, GSH1 ENSG00000169840 GS homeobox 1 13 27792643-27794768 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA047096 Uncertain Not detected cerebral cortex: 0.7 -PCDH7 BH-Pcdh, PPP1R120 ENSG00000169851 Protocadherin 7 4 30720415-31146805 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011866, HPA046521 Uncertain Validated Plasma membrane
Cell Junctions Mixed cerebral cortex: 46.1 -ROBO1 DUTT1, FLJ21882, SAX3 ENSG00000169855 Roundabout guidance receptor 1 3 78597240-79767815 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013524, HPA052968 Uncertain Supported Plasma membrane Mixed cerebral cortex: 33.0 -ONECUT1 HNF-6, HNF6, HNF6A ENSG00000169856 One cut homeobox 1 15 52756989-52791078 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA003457 Approved Group enriched 6 gallbladder: 8.5;liver: 5.9;pancreas: 2.3;testis: 1.8 bone marrow: 0.7 -AVEN PDCD12 ENSG00000169857 Apoptosis, caspase activation inhibitor 15 33866227-34039176 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020863 Approved Approved Plasma membrane
Actin filaments
Centrosome Expressed in all smooth muscle: 19.1 -P2RY1 P2Y1 ENSG00000169860 Purinergic receptor P2Y, G-protein coupled, 1 3 152834693-152841439 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015577 Approved Tissue enhanced 0 placenta: 33.7 esophagus: 20.0 -CTNND2 GT24, NPRAP ENSG00000169862 Catenin (cadherin-associated protein), delta 2 5 10971840-11904043 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015077, CAB037339 Supported Approved Nucleoplasm
Golgi apparatus
Cell Junctions Tissue enriched 18 cerebral cortex: 103.5 spleen: 5.7 -TRIM56 RNF109 ENSG00000169871 Tripartite motif containing 56 7 101085439-101097967 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024358 Approved Approved Nucleoplasm
Cytosol Expressed in all spleen: 30.1 -MUC17 ENSG00000169876 Mucin 17, cell surface associated 7 101020072-101058745 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031634 Supported Group enriched 8 duodenum: 22.4;small intestine: 43.3 rectum: 3.9 -AHSP EDRF, ERAF ENSG00000169877 Alpha hemoglobin stabilizing protein 16 31527864-31528803 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040940 Supported Tissue enriched 26 bone marrow: 884.2 placenta: 33.9 -WNT10B SHFM6, WNT-12 ENSG00000169884 Wingless-type MMTV integration site family, member 10B 12 48965340-48971763 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA055048, HPA062539 Approved Approved Golgi apparatus Tissue enhanced 0 cerebral cortex: 11.6 skin: 3.0 -CALML6 CAGLP ENSG00000169885 Calmodulin-like 6 1 1914827-1917296 Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 9 skeletal muscle: 37.6 esophagus: 4.2 -REPS2 POB1 ENSG00000169891 RALBP1 associated Eps domain containing 2 X 16946691-17153280 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000565, HPA026073 Uncertain Mixed cerebral cortex: 28.9 -MUC3A MUC3 ENSG00000169894 Mucin 3A, cell surface associated 7 100949555-100968346 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA010871 Uncertain Tissue enhanced 0 duodenum: 42.7;gallbladder: 21.9;small intestine: 37.9 rectum: 14.7 -SYAP1 FLJ14495, PRO3113 ENSG00000169895 Synapse associated protein 1 X 16719632-16765336 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000175, HPA000882, HPA048047 Approved Validated Nucleoplasm
Golgi apparatus
Cytosol Expressed in all adrenal gland: 33.7 -ITGAM CD11B, CR3A, MAC-1 ENSG00000169896 Integrin, alpha M (complement component 3 receptor 3 subunit) 16 31259990-31332892 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002274, CAB025091, CAB072870 Supported Tissue enhanced 0 bone marrow: 130.4 appendix: 37.1 -PYDC1 ASC2, POP1 ENSG00000169900 PYD (pyrin domain) containing 1 16 31215962-31217359 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 8 skin: 4.3 cerebral cortex: 0.5 -TPST1 TANGO13A ENSG00000169902 Tyrosylprotein sulfotransferase 1 7 66205199-66420543 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047415 Approved Approved Cytosol Mixed gallbladder: 55.8 -TM4SF4 il-TMP ENSG00000169903 Transmembrane 4 L six family member 4 3 149473974-149503281 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046430 Supported Approved Plasma membrane
Cytosol Group enriched 34 duodenum: 595.8;gallbladder: 1326.5;liver: 343.7;small intestine: 515.2 stomach: 20.3 -TOR1AIP2 IFRG15, LULL1, NET9 ENSG00000169905 Torsin A interacting protein 2 1 179839967-179877803 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051849, HPA058348, HPA070542 Uncertain Validated Endoplasmic reticulum Expressed in all placenta: 33.9 -S100G CABP1, CABP9K, CALB3 ENSG00000169906 S100 calcium binding protein G X 16650158-16654670 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence CAB017688, HPA055873 Supported Tissue enriched 11 duodenum: 247.6 small intestine: 23.3 -TM4SF1 L6, M3S1 ENSG00000169908 Transmembrane 4 L six family member 1 3 149369022-149377865 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002760, HPA002823 Uncertain Expressed in all gallbladder: 328.4 -OTUD3 DUBA4, KIAA0459 ENSG00000169914 OTU deubiquitinase 3 1 19882513-19912945 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028543, HPA028544 Approved Approved Nucleoplasm
Intermediate filaments
Cytosol Mixed testis: 19.3 -OTUD7A C15orf16, CEZANNE2, OTUD7 ENSG00000169918 OTU deubiquitinase 7A 15 31475398-31870789 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044554 Uncertain Approved Nucleoli
Cytosol Tissue enhanced 0 cerebral cortex: 13.5 testis: 5.1 -GUSB ENSG00000169919 Glucuronidase, beta 7 65960684-65982314 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036322, HPA036323 Approved Supported Vesicles Expressed in all breast: 94.1 -BRD3 KIAA0043, ORFX, RING3L ENSG00000169925 Bromodomain containing 3 9 134030305-134068535 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051830 Approved Approved Nuclear bodies Expressed in all cerebral cortex: 21.4 -KLF13 BTEB3, FKLF-2, NSLP1, RFLAT-1 ENSG00000169926 Kruppel-like factor 13 15 31326855-31435665 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all bone marrow: 37.8 -FRMPD4 KIAA0316, PDZD10, PDZK10 ENSG00000169933 FERM and PDZ domain containing 4 X 12138466-12724523 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035580 Uncertain Group enriched 32 cerebral cortex: 15.5;parathyroid gland: 23.8 heart muscle: 0.6 -ZFPM2 FOG2, hFOG-2, ZC2HC11B, ZNF89B ENSG00000169946 Zinc finger protein, FOG family member 2 8 104590733-105804532 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004094 Approved Supported Nucleoplasm Tissue enhanced 0 ovary: 40.6 smooth muscle: 25.8 -ZNF764 MGC13138 ENSG00000169951 Zinc finger protein 764 16 30553764-30558498 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA003203 Uncertain Approved Cytosol Mixed testis: 6.0 -HSFY2 FLJ25453 ENSG00000169953 Heat shock transcription factor, Y-linked 2 Y 18731440-18828662 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 175 testis: 24.5 kidney: 0.1 -ZNF747 MGC2474 ENSG00000169955 Zinc finger protein 747 16 30530367-30535347 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA003203, HPA069173 Uncertain Approved Centrosome
Cytosol Mixed parathyroid gland: 15.4 -ZNF768 FLJ23436 ENSG00000169957 Zinc finger protein 768 16 30524001-30526821 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024630, HPA066512 Supported Approved Nucleus
Vesicles Expressed in all parathyroid gland: 55.0 -TAS1R3 T1R3 ENSG00000169962 Taste receptor, type 1, member 3 1 1331314-1335306 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053439 Approved Group enriched 5 epididymis: 14.7;salivary gland: 3.3 appendix: 1.7 -TMEM42 MGC29956 ENSG00000169964 Transmembrane protein 42 3 44861869-44865670 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052569 Uncertain Expressed in all epididymis: 12.5 -MAP3K2 MEKK2, MEKK2B ENSG00000169967 Mitogen-activated protein kinase kinase kinase 2 2 127298730-127388465 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021540 Approved Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 29.7 -PUSL1 FLJ90811 ENSG00000169972 Pseudouridylate synthase-like 1 1 1308567-1311677 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032057, HPA039999 Uncertain Validated Vesicles Expressed in all skin: 9.1 -SF3B5 MGC3133, SF3b10, Ysf3 ENSG00000169976 Splicing factor 3b, subunit 5, 10kDa 6 144094881-144095573 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054408 Approved Validated Nucleoplasm Expressed in all fallopian tube: 201.6 -ZNF35 HF.10, HF10, Zfp105 ENSG00000169981 Zinc finger protein 35 3 44648727-44660791 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051859, HPA054738 Uncertain Approved Nucleoplasm Mixed testis: 9.2 -TIGD4 ENSG00000169989 Tigger transposable element derived 4 4 152769354-152779764 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035649 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 8.5 fallopian tube: 3.2 -IFFO2 ENSG00000169991 Intermediate filament family orphan 2 1 18904281-18956686 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA015987, HPA064603 Approved Approved Nucleoplasm
Plasma membrane Expressed in all skin: 72.6 -NLGN2 KIAA1366 ENSG00000169992 Neuroligin 2 17 7404874-7419860 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055321, HPA069278 Supported Approved Mitochondria Tissue enhanced 0 cerebral cortex: 81.7 endometrium: 43.6 -MYO7B ENSG00000169994 Myosin VIIB 2 127535802-127637729 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039131 Approved Tissue enhanced 0 duodenum: 117.1;small intestine: 94.0 colon: 35.9 -CHD3 Mi-2a, Mi2-ALPHA, ZFH ENSG00000170004 Chromodomain helicase DNA binding protein 3 17 7884806-7912760 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043368, HPA076524 Supported Approved Nucleus
Nucleoli
Microtubule organizing center Expressed in all parathyroid gland: 83.9 -TMEM154 FLJ32028 ENSG00000170006 Transmembrane protein 154 4 152618632-152680165 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA019184, HPA055411 Uncertain Approved Nucleoplasm
Nuclear membrane Tissue enhanced 0 esophagus: 64.6;skin: 69.4 tonsil: 25.3 -MYRIP DKFZp586F1018, exophilin-8, MyRIP, SLAC2-C, SLAC2C ENSG00000170011 Myosin VIIA and Rab interacting protein 3 39808914-40260321 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006433 Approved Nucleus
Nucleoli
Golgi apparatus Tissue enhanced 0 cerebral cortex: 20.7 spleen: 10.1 -ALCAM CD166, MEMD ENSG00000170017 Activated leukocyte cell adhesion molecule 3 105366909-105576900 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002148, HPA010926 Approved Tissue enhanced 0 parathyroid gland: 462.8 lung: 111.3 -YWHAG PPP1R170 ENSG00000170027 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 7 76326794-76359031 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013274, CAB018389, HPA026918 Approved Expressed in all cerebral cortex: 613.3 -UBE2E3 UbcH9 ENSG00000170035 Ubiquitin-conjugating enzyme E2E 3 2 180967248-181076585 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003303, HPA030445 Approved Expressed in all parathyroid gland: 129.1 -CNTROB LIP8, PP1221 ENSG00000170037 Centrobin, centrosomal BRCA2 interacting protein 17 7932101-7949918 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023319, HPA023320, HPA023321, HPA023325 Approved Supported Centrosome
Cytosol Expressed in all testis: 91.0 -TRAPPC1 BET5, MUM2 ENSG00000170043 Trafficking protein particle complex 1 17 7930345-7932123 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052398 Approved Expressed in all placenta: 163.9 -ZPLD1 ENSG00000170044 Zona pellucida-like domain containing 1 3 102099244-102479841 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 gallbladder: 3.5;testis: 1.3 duodenum: 0.9 -KCNAB3 AKR6A9, KCNA3B ENSG00000170049 Potassium channel, voltage gated subfamily A regulatory beta subunit 3 17 7921859-7929803 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA077993 Approved Mitochondria Tissue enhanced 0 endometrium: 14.5;smooth muscle: 8.5 cerebral cortex: 4.7 -SERPINA9 CENTERIN, GCET1, SERPINA11b ENSG00000170054 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 14 94462717-94479689 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 10 appendix: 17.7;lymph node: 51.0;tonsil: 68.9 epididymis: 4.5 -FAM153A NY-REN-7 ENSG00000170074 Family with sequence similarity 153, member A 5 177707981-177783398 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042585, HPA044022, HPA046691, HPA052337, HPA055498 Uncertain Tissue enriched 5 testis: 14.3 ovary: 2.8 -GPR37L1 ETBR-LP-2 ENSG00000170075 G protein-coupled receptor 37 like 1 1 202122858-202133592 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064454 Supported Tissue enriched 61 cerebral cortex: 34.2 seminal vesicle: 0.5 -SIMC1 C5orf25, FLJ44216, OOMA1, PLEIAD ENSG00000170085 SUMO-interacting motifs containing 1 5 176238367-176345991 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037889, HPA037890 Approved Supported Nucleus
Nucleoli fibrillar center Tissue enhanced 0 testis: 71.4 ovary: 58.5 -TMEM192 FLJ38482 ENSG00000170088 Transmembrane protein 192 4 165070608-165208549 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014717, HPA024110 Supported Validated Nucleoplasm
Endosomes
Lysosomes Expressed in all kidney: 50.6 -HMP19 ENSG00000170091 HMP19 protein 5 174045604-174243501 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA056191 Supported Approved Golgi apparatus Tissue enriched 7 cerebral cortex: 289.3 adrenal gland: 42.2 -SPDYE5 ENSG00000170092 Speedy/RINGO cell cycle regulator family member E5 7 75493625-75504304 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA044799, HPA051750 Uncertain Tissue enhanced 0 testis: 5.2 skin: 2.2 -SERPINA6 CBG ENSG00000170099 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 14 94304248-94323394 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017864 Approved Tissue enriched 6 liver: 216.6 gallbladder: 34.1 -ZNF778 FLJ31875 ENSG00000170100 Zinc finger protein 778 16 89217703-89237071 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052057, HPA057151 Uncertain Supported Nucleus
Nuclear bodies Mixed parathyroid gland: 14.9 -NIPA1 MGC35570, SPG6 ENSG00000170113 Non imprinted in Prader-Willi/Angelman syndrome 1 15 22773063-22829791 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023269 Uncertain Tissue enhanced 0 cerebral cortex: 38.3 parathyroid gland: 16.6 -FOXD4 FKHL9, FOXD4a, FREAC5 ENSG00000170122 Forkhead box D4 9 116231-118204 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA012836 Uncertain Approved Nucleus Tissue enhanced 0 testis: 1.0 cerebral cortex: 0.3 -GPR25 ENSG00000170128 G protein-coupled receptor 25 1 200873038-200874123 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 stomach: 1.7 lung: 0.6 -UBE2E1 UbcH6 ENSG00000170142 Ubiquitin-conjugating enzyme E2E 1 3 23805903-23891316 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030445, CAB073413 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 119.1 -HNRNPA3 HNRPA3 ENSG00000170144 Heterogeneous nuclear ribonucleoprotein A3 2 177212563-177223958 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001666, HPA005812, HPA066381 Supported Validated Nucleoplasm Expressed in all appendix: 316.2 -SIK2 DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2 ENSG00000170145 Salt-inducible kinase 2 11 111602391-111730853 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016026 Approved Approved Golgi apparatus Expressed in all adipose tissue: 32.3 -RNF150 KIAA1214 ENSG00000170153 Ring finger protein 150 4 140859807-141212877 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037987 Uncertain Mixed endometrium: 21.2 -CCDC144A FLJ43983, KIAA0565 ENSG00000170160 Coiled-coil domain containing 144A 17 16689537-16777881 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022996, HPA047220, HPA047851 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 testis: 16.7 endometrium: 6.3 -VGLL2 ENSG00000170162 Vestigial-like family member 2 6 117265558-117273565 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 15 skeletal muscle: 45.1 heart muscle: 2.9 -HOXD4 HOX4, HOX4B ENSG00000170166 Homeobox D4 2 176151222-176153226 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA054383, HPA070349 Approved Validated Nucleus
Cell Junctions Tissue enhanced 0 endometrium: 23.5;epididymis: 22.6 fallopian tube: 15.4 -CHRNB1 CHRNB ENSG00000170175 Cholinergic receptor, nicotinic, beta 1 (muscle) 17 7445061-7457707 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA005822, CAB011200 Approved Expressed in all skeletal muscle: 43.9 -HOXD12 HOX4H ENSG00000170178 Homeobox D12 2 176099730-176101193 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA059444 Uncertain Tissue enhanced 0 colon: 1.0;rectum: 1.1;seminal vesicle: 1.8 prostate: 0.8 -GYPA CD235a, GPA, MN, MNS ENSG00000170180 Glycophorin A (MNS blood group) 4 144109303-144140751 Blood group antigen proteins, CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002658, HPA014811 Supported Tissue enriched 16 bone marrow: 84.8 placenta: 5.3 -USP38 HP43.8KD, KIAA1891 ENSG00000170185 Ubiquitin specific peptidase 38 4 143184917-143223830 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036990, HPA047948 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 13.8 -SLC16A5 MCT5, MCT6 ENSG00000170190 Solute carrier family 16 (monocarboxylate transporter), member 5 17 75087727-75106162 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed duodenum: 35.5 -NANP C20orf147, dJ694B14.3, HDHD4, MGC26833 ENSG00000170191 N-acetylneuraminic acid phosphatase 20 25612935-25624175 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050342 Uncertain Approved Nuclear membrane Mixed testis: 4.9 -ANKK1 X-kinase ENSG00000170209 Ankyrin repeat and kinase domain containing 1 11 113387791-113400418 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012813 Uncertain Tissue enhanced 0 skin: 4.2 fallopian tube: 1.3 -ADRA1B ENSG00000170214 Adrenoceptor alpha 1B 5 159916783-159972544 Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA074416 Supported Plasma membrane Tissue enhanced 0 cerebral cortex: 14.8;spleen: 17.3 ovary: 4.8 -ADPRM C17orf48, MDS006 ENSG00000170222 ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 17 10697594-10711233 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA023265, HPA023820 Approved Expressed in all prostate: 18.1 -FABP6 I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP ENSG00000170231 Fatty acid binding protein 6, ileal 5 160187367-160238735 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012601, CAB024713 Supported Tissue enriched 50 small intestine: 4287.7 fallopian tube: 85.2 -PWWP2A KIAA1935 ENSG00000170234 PWWP domain containing 2A 5 160061801-160119423 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046733, HPA058233 Uncertain Supported Nucleoplasm
Focal adhesion sites Expressed in all cervix: 15.4 -USP50 ENSG00000170236 Ubiquitin specific peptidase 50 15 50500562-50546708 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039470 Uncertain Tissue enriched 17 testis: 1.9 parathyroid gland: 0.1 -USP47 ENSG00000170242 Ubiquitin specific peptidase 47 11 11841423-11959323 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029286, HPA029289 Supported Approved Intermediate filaments Expressed in all parathyroid gland: 75.5 -PDCD6IP AIP1, Alix, Hp95 ENSG00000170248 Programmed cell death 6 interacting protein 3 33798352-33869707 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011905, CAB016212 Approved Validated Cytosol Expressed in all parathyroid gland: 63.2 -MRGPRX1 MRGX1 ENSG00000170255 MAS-related GPR, member X1 11 18933813-18939507 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -ZNF212 C2H2-150 ENSG00000170260 Zinc finger protein 212 7 149239651-149255609 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049807, HPA054178 Uncertain Supported Nucleus Expressed in all testis: 15.4 -MRAP B27, C21orf61, FALP ENSG00000170262 Melanocortin 2 receptor accessory protein 21 32291813-32314784 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011024 Uncertain Group enriched 8 adipose tissue: 51.9;adrenal gland: 65.6 breast: 6.9 -FAM161A FLJ13305, RP28 ENSG00000170264 Family with sequence similarity 161, member A 2 61824854-61854143 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032119 Approved Tissue enhanced 0 testis: 9.9 fallopian tube: 6.4 -ZNF282 HUB1 ENSG00000170265 Zinc finger protein 282 7 149195485-149226248 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024374 Supported Approved Nucleoplasm
Cytosol Expressed in all cervix: 14.8 -GLB1 EBP, ELNR1 ENSG00000170266 Galactosidase, beta 1 3 32996608-33097230 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008382, HPA040610, HPA069503 Supported Supported Golgi apparatus
Vesicles Expressed in all epididymis: 120.4 -C14orf142 ENSG00000170270 Chromosome 14 open reading frame 142 14 93202894-93207094 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051832 Approved Approved Nucleus
Nucleoli Mixed fallopian tube: 30.8 -FAXDC2 C5orf4, FLJ13758 ENSG00000170271 Fatty acid hydroxylase domain containing 2 5 154818491-154859252 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 parathyroid gland: 381.3 ovary: 66.6 -CRTAP CASP, LEPREL3, P3H5 ENSG00000170275 Cartilage associated protein 3 33113979-33147773 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043598, HPA044150 Approved Approved Intermediate filaments
Actin filaments
Cytosol Expressed in all cervix: 196.9 -HSPB2 Hs.78846, MKBP ENSG00000170276 Heat shock 27kDa protein 2 11 111912242-111914093 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 heart muscle: 35.4 skeletal muscle: 25.0 -C7orf33 ENSG00000170279 Chromosome 7 open reading frame 33 7 148590565-148615860 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected testis: 0.3 -CNGB3 ACHM1, ACHM3, RMCH ENSG00000170289 Cyclic nucleotide gated channel beta 3 8 86553977-86743675 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057244 Approved Tissue enhanced 0 testis: 4.0 bone marrow: 2.7 -SLN MGC12301, MGC125854, MGC125855 ENSG00000170290 Sarcolipin 11 107707378-107719693 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level CAB011628 Approved Microtubules Tissue enriched 11 skeletal muscle: 2802.5 heart muscle: 263.2 -ELP5 C17orf81, DERP6 ENSG00000170291 Elongator acetyltransferase complex subunit 5 17 7251416-7259940 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023279 Uncertain Supported Cytosol Expressed in all testis: 172.8 -CMTM8 CKLFSF8 ENSG00000170293 CKLF-like MARVEL transmembrane domain containing 8 3 32238679-32370325 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055077, HPA073258 Approved Approved Nucleoplasm Mixed placenta: 24.7 -GABARAP ATG8A, MM46 ENSG00000170296 GABA(A) receptor-associated protein 17 7240014-7242770 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065883 Approved Vesicles Expressed in all epididymis: 750.2 -LGALS9B ENSG00000170298 Lectin, galactoside-binding, soluble, 9B 17 20449395-20467539 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046876, HPA047218 Approved Uncertain Cytosol Tissue enhanced 0 gallbladder: 11.7;rectum: 12.0;stomach: 29.2 colon: 7.7 -STX8 CARB ENSG00000170310 Syntaxin 8 17 9250471-9576591 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001540 Approved Uncertain Nuclear bodies
Golgi apparatus
Actin filaments
Cytosol Expressed in all testis: 96.0 -CDK1 CDC2, CDC28A ENSG00000170312 Cyclin-dependent kinase 1 10 60778331-60794852 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003387, CAB003799 Uncertain Validated Nucleus
Cytosol Mixed lymph node: 48.1 -UBB FLJ25987, MGC8385 ENSG00000170315 Ubiquitin B 17 16380798-16382745 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB013048, HPA041344, HPA049132 Supported Expressed in all testis: 2227.1 -NFRKB DKFZp547B2013, INO80G ENSG00000170322 Nuclear factor related to kappaB binding protein 11 129863636-129895590 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007082, HPA007128 Approved Validated Nucleus Expressed in all testis: 38.0 -FABP4 A-FABP, aP2 ENSG00000170323 Fatty acid binding protein 4, adipocyte 8 81478419-81483263 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002188, CAB024961 Supported Tissue enriched 7 adipose tissue: 3642.8 breast: 553.6 -FRMPD2 MGC35285, PDZD5C, PDZK5C ENSG00000170324 FERM and PDZ domain containing 2 10 48156558-48274870 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045059 Uncertain Group enriched 6 cerebral cortex: 3.9;fallopian tube: 5.3;testis: 2.9 thyroid gland: 0.7 -PRDM10 KIAA1231, MGC131802, PFM7 ENSG00000170325 PR domain containing 10 11 129899706-130002835 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026997 Approved Approved Nucleoplasm
Nucleoli fibrillar center
Vesicles Mixed parathyroid gland: 7.4 -B3GNT2 B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT ENSG00000170340 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 2 62196113-62224731 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005997 Approved Approved Vesicles Expressed in all lung: 51.0 -FOS AP-1, c-fos ENSG00000170345 FBJ murine osteosarcoma viral oncogene homolog 14 75278774-75282230 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018531 Approved Supported Nucleoplasm Expressed in all fallopian tube: 1834.8 -TMED10 p23, P24(DELTA), p24d1, p24delta1, TMP21 ENSG00000170348 Transmembrane p24 trafficking protein 10 14 75131470-75176631 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034442, CAB037251, HPA047139, HPA050539 Supported Supported Golgi apparatus Expressed in all thyroid gland: 243.4 -SETMAR metnase ENSG00000170364 SET domain and mariner transposase fusion gene 3 4303304-4317567 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057999 Supported Nucleoli Expressed in all smooth muscle: 15.9 -SMAD1 JV4-1, MADH1, MADR1 ENSG00000170365 SMAD family member 1 4 145481194-145558079 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005389 Approved Supported Nucleus
Plasma membrane
Cytosol Expressed in all parathyroid gland: 69.4 -CST5 ENSG00000170367 Cystatin D 20 23875935-23879750 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB024944, HPA061449 Supported Tissue enriched 370 salivary gland: 760.2 smooth muscle: 2.0 -CST2 ENSG00000170369 Cystatin SA 20 23823769-23826731 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB024963, HPA043706, HPA044763 Supported Tissue enriched 280 salivary gland: 2062.3 gallbladder: 7.3 -EMX2 ENSG00000170370 Empty spiracles homeobox 2 10 117542444-117549546 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA003497, HPA065294 Approved Supported Approved Nucleus Group enriched 5 cervix, uterine: 59.4;endometrium: 114.7;epididymis: 113.9;fallopian tube: 72.9;kidney: 38.3;seminal vesicle: 64.9;smooth muscle: 59.6 cerebral cortex: 14.0 -CST1 ENSG00000170373 Cystatin SN 20 23747553-23751268 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026769, HPA043706, HPA044763 Supported Tissue enriched 27 salivary gland: 9637.4 gallbladder: 354.6 -SP7 osterix, OSX ENSG00000170374 Sp7 transcription factor 12 53326575-53345315 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029964, HPA063202 Approved Approved Tissue enhanced 0 testis: 1.3 parathyroid gland: 0.4 -TCAF2 FAM115C, FAM139A, FLJ40722 ENSG00000170379 TRPM8 channel-associated factor 2 7 143620950-143730409 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038756, HPA038758 Uncertain Supported Endoplasmic reticulum
Plasma membrane
Cell Junctions Mixed placenta: 8.4 -SEMA3E coll-5, KIAA0331, M-SemaK, SEMAH ENSG00000170381 Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 7 83363906-83649010 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029419, HPA063804 Uncertain Supported Approved Nucleoplasm
Vesicles Mixed prostate: 8.1 -LRRN2 FIGLER7, GAC1, LRANK1, LRRN5 ENSG00000170382 Leucine rich repeat neuronal 2 1 204617170-204685733 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029124 Uncertain Approved Endoplasmic reticulum Tissue enhanced 0 cerebral cortex: 23.4;parathyroid gland: 21.0 fallopian tube: 11.9 -SLC30A1 ZNT1, ZRC1 ENSG00000170385 Solute carrier family 30 (zinc transporter), member 1 1 211571568-211578742 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015275, HPA049000 Uncertain Supported Vesicles
Plasma membrane Mixed liver: 47.3 -DCLK2 DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428 ENSG00000170390 Doublecortin-like kinase 2 4 150078274-150257457 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA015770 Supported Tissue enriched 11 cerebral cortex: 82.8 heart muscle: 7.4 -ZNF804A C2orf10 ENSG00000170396 Zinc finger protein 804A 2 184598366-184939492 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029195 Uncertain Approved Endoplasmic reticulum Tissue enhanced 0 cerebral cortex: 6.4 thyroid gland: 2.7 -GPRC5C RAIG-3 ENSG00000170412 G protein-coupled receptor, class C, group 5, member C 17 74424851-74451653 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029776 Supported Uncertain Nucleus
Microtubule organizing center
Cytosol Mixed thyroid gland: 103.7 -TMEM182 FLJ30294 ENSG00000170417 Transmembrane protein 182 2 102736908-102843893 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045861 Uncertain Approved Nucleoplasm
Vesicles Group enriched 10 heart muscle: 60.3;skeletal muscle: 44.1 prostate: 5.0 -VSTM2A MGC33530, VSTM2 ENSG00000170419 V-set and transmembrane domain containing 2A 7 54542325-54571080 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA021404, HPA024134 Uncertain Tissue enhanced 0 adrenal gland: 12.7;cerebral cortex: 40.9;prostate: 13.4 stomach: 4.8 -KRT8 CARD2, CK8, CYK8, K2C8, K8, KO ENSG00000170421 Keratin 8, type II 12 52897187-52949954 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000131, CAB001696, HPA049866 Supported Supported Intermediate filaments Tissue enhanced 0 small intestine: 1505.1 duodenum: 1149.4 -KRT78 K5B ENSG00000170423 Keratin 78, type II 12 52837804-52849092 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039724 Supported Tissue enriched 8 esophagus: 1058.9 tonsil: 132.4 -ADORA2B ENSG00000170425 Adenosine A2b receptor 17 15944917-15975746 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA073747 Uncertain Cytosol Mixed colon: 8.3 -SDR9C7 RDHS, SDR-O ENSG00000170426 Short chain dehydrogenase/reductase family 9C, member 7 12 56923154-56934405 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039059 Approved Nucleoli
Cytosol Tissue enhanced 0 esophagus: 10.7;skin: 46.2 tonsil: 7.1 -MGMT ENSG00000170430 O-6-methylguanine-DNA methyltransferase 10 129467184-129768007 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002786, HPA032135, HPA032136 Approved Validated Nucleoplasm Expressed in all fallopian tube: 25.8 -METTL7B ALDI, MGC17301 ENSG00000170439 Methyltransferase like 7B 12 55681546-55684611 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038644 Supported Supported Vesicles
Microtubules Tissue enhanced 0 epididymis: 134.9;liver: 121.9 duodenum: 53.4 -KRT86 Hb6, KRTHB6, MNX ENSG00000170442 Keratin 86, type II 12 52249300-52309163 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039798, HPA049778 Supported Approved Cytosol Tissue enhanced 0 thyroid gland: 7.8 testis: 2.4 -HARS ENSG00000170445 Histidyl-tRNA synthetase 5 140673173-140692024 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036539 Approved Validated Cytosol Expressed in all cerebral cortex: 71.3 -NFXL1 HOZFP ENSG00000170448 Nuclear transcription factor, X-box binding-like 1 4 47847233-47914667 Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059132 Approved Approved Nucleoplasm Mixed testis: 24.8 -KRT75 K6HF ENSG00000170454 Keratin 75, type II 12 52424070-52434525 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019367, HPA076201 Supported Approved Plasma membrane
Cytosol Not detected breast: 0.9 -DENND5B MGC24039 ENSG00000170456 DENN/MADD domain containing 5B 12 31382223-31591097 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038865 Approved Approved Nucleoli
Microtubules Mixed testis: 29.1 -CD14 ENSG00000170458 CD14 molecule 5 140631728-140633701 Cancer-related genes, CD markers, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001887, HPA002127, CAB033631, CAB072865, CAB072866 Supported Supported Vesicles Expressed in all appendix: 273.9 -DNAJC18 MGC29463 ENSG00000170464 DnaJ (Hsp40) homolog, subfamily C, member 18 5 139408588-139444491 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036538, HPA060154 Approved Supported Cell Junctions Group enriched 5 cerebral cortex: 30.2;testis: 115.2 ovary: 13.8 -KRT6C KRT6E ENSG00000170465 Keratin 6C, type II 12 52468516-52473785 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045697, HPA061168 Supported Supported Intermediate filaments Tissue enriched 50 esophagus: 527.3 cervix: 10.5 -C14orf169 FLJ21802, MAPJD, NO66 ENSG00000170468 Chromosome 14 open reading frame 169 14 73490964-73493392 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003730 Supported Nucleoli Expressed in all testis: 17.7 -SPATA24 CCDC161, T6441 ENSG00000170469 Spermatogenesis associated 24 5 139396563-139404088 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044000 Supported Supported Nucleus
Cytosol Tissue enriched 7 testis: 176.4 epididymis: 25.2 -RALGAPB DKFZp781M2411, KIAA1219, RalGAPbeta ENSG00000170471 Ral GTPase activating protein, beta subunit (non-catalytic) 20 38472816-38578861 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051454 Approved Approved Nuclear speckles Expressed in all parathyroid gland: 45.4 -PYM1 PYM, WIBG ENSG00000170473 PYM homolog 1, exon junction complex associated factor 12 55901413-55932618 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012803, HPA039717, HPA046200 Supported Supported Nucleus
Nucleoli
Cell Junctions
Cytosol Expressed in all esophagus: 50.5 -MZB1 HSPC190, MEDA-7, MGC29506, PACAP, pERp1 ENSG00000170476 Marginal zone B and B1 cell-specific protein 5 139387480-139390081 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043745, HPA052694 Supported Mixed lymph node: 163.6 -KRT4 CK4, CYK4, K4 ENSG00000170477 Keratin 4, type II 12 52806549-52814551 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002154, HPA034881 Supported Validated Intermediate filaments Tissue enriched 24 esophagus: 14911.0 tonsil: 623.1 -SLC23A1 SLC23A2, SVCT1, YSPL3 ENSG00000170482 Solute carrier family 23 (ascorbic acid transporter), member 1 5 139367196-139384553 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047612 Supported Group enriched 5 duodenum: 27.5;fallopian tube: 85.7;kidney: 41.7;small intestine: 73.4 liver: 10.7 -KRT74 K6IRS4, KRT5C, KRT6IRS4 ENSG00000170484 Keratin 74, type II 12 52565782-52573825 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048596 Uncertain Tissue enriched 6 epididymis: 6.8 breast: 1.1 -NPAS2 bHLHe9, MOP4, PASD4 ENSG00000170485 Neuronal PAS domain protein 2 2 100820152-100996829 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019674 Uncertain Supported Approved Nucleoplasm Mixed esophagus: 27.5 -KRT72 K6irs, K6IRS2, KRT6, KRT6IRS2 ENSG00000170486 Keratin 72, type II 12 52585589-52601538 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065523 Supported Tissue enriched 5 testis: 26.7 skin: 5.2 -KISS1 ENSG00000170498 KiSS-1 metastasis-suppressor 1 204190341-204196486 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017775, HPA035542 Supported Approved Vesicles Tissue enriched 86 placenta: 328.0 stomach: 3.8 -LONRF2 FLJ45273, RNF192 ENSG00000170500 LON peptidase N-terminal domain and ring finger 2 2 100273291-100322733 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA057366 Supported Nucleus Tissue enhanced 0 epididymis: 54.9 endometrium: 44.9 -NUDT9 MGC3037 ENSG00000170502 Nudix (nucleoside diphosphate linked moiety X)-type motif 9 4 87422582-87459454 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036917, HPA044866, HPA078535 Approved Supported Nuclear membrane
Cell Junctions
Mitochondria Expressed in all parathyroid gland: 84.9 -HSD17B13 SCDR9, SDR16C3 ENSG00000170509 Hydroxysteroid (17-beta) dehydrogenase 13 4 87303789-87322906 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029125 Uncertain Approved Golgi apparatus
Vesicles Tissue enriched 29 liver: 293.7 adipose tissue: 10.2 -PA2G4 ENSG00000170515 Proliferation-associated 2G4, 38kDa 12 56104319-56113907 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011711, CAB012428, HPA016484 Supported Approved Cytosol Expressed in all parathyroid gland: 136.0 -COX7B2 ENSG00000170516 Cytochrome c oxidase subunit VIIb2 4 46734827-46909235 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 100 testis: 147.6 placenta: 1.4 -ELOVL6 FLJ23378, LCE, MGC5487 ENSG00000170522 ELOVL fatty acid elongase 6 4 110045846-110199199 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042355 Uncertain Mixed liver: 27.9 -KRT83 Hb-3, KRTHB3 ENSG00000170523 Keratin 83, type II 12 52314301-52321398 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049778 Supported Tissue enhanced 0 thyroid gland: 1.7 testis: 0.3 -PFKFB3 ENSG00000170525 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 10 6144934-6235545 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008266, CAB020795, HPA043889 Uncertain Validated Nucleoplasm Expressed in all adipose tissue: 343.9 -TMC7 FLJ21240 ENSG00000170537 Transmembrane channel-like 7 16 18983934-19063942 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029465 Uncertain Approved Vesicles Tissue enhanced 0 testis: 17.7 cerebral cortex: 10.7 -ARL6IP1 AIP1, ARL6IP, ARMER, KIAA0069, SPG61 ENSG00000170540 ADP-ribosylation factor-like 6 interacting protein 1 16 18791667-18801678 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045307 Uncertain Approved Endoplasmic reticulum Expressed in all cerebral cortex: 388.0 -SERPINB9 CAP3, PI9 ENSG00000170542 Serpin peptidase inhibitor, clade B (ovalbumin), member 9 6 2887266-2903280 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030067 Uncertain Tissue enhanced 0 placenta: 74.3 appendix: 49.8 -SMAGP hSMAGP, MGC149453, MGC149454 ENSG00000170545 Small cell adhesion glycoprotein 12 51244558-51270890 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039711 Approved Supported Nucleoplasm
Plasma membrane Tissue enhanced 0 placenta: 144.1 esophagus: 83.7 -IRX1 IRX-5 ENSG00000170549 Iroquois homeobox 1 5 3596054-3601403 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA043160 Uncertain Supported Nucleoplasm
Golgi apparatus Tissue enhanced 0 breast: 7.7;kidney: 5.3;salivary gland: 5.7 lung: 3.6 -CDH2 CD325, CDHN, NCAD ENSG00000170558 Cadherin 2, type 1, N-cadherin (neuronal) 18 27950966-28177446 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000141, CAB018580, HPA058574 Supported Supported Plasma membrane
Cell Junctions Tissue enhanced 0 heart muscle: 125.8;parathyroid gland: 124.0 adrenal gland: 87.7 -IRX2 ENSG00000170561 Iroquois homeobox 2 5 2745845-2751662 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA050895, HPA054669 Approved Approved Nucleus
Nucleoli Tissue enhanced 0 breast: 29.4;lung: 28.1 skin: 19.6 -EMB MGC71745 ENSG00000170571 Embigin 5 50396192-50443248 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed bone marrow: 94.9 -SIX2 ENSG00000170577 SIX homeobox 2 2 45005161-45009430 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA052782, HPA056958 Uncertain Supported Nucleoplasm
Nuclear membrane Group enriched 5 cervix, uterine: 18.6;parathyroid gland: 8.5;prostate: 6.1;salivary gland: 9.5;skeletal muscle: 6.7 adipose tissue: 1.9 -DLGAP1 DAP-1, GKAP, SAPAP1 ENSG00000170579 Discs, large (Drosophila) homolog-associated protein 1 18 3496032-4455335 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 cerebral cortex: 90.3 seminal vesicle: 14.4 -STAT2 STAT113 ENSG00000170581 Signal transducer and activator of transcription 2, 113kDa 12 56341597-56360155 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003858, HPA018888 Approved Supported Plasma membrane
Cytosol Expressed in all spleen: 48.7 -NUDCD2 DKFZp686E10109 ENSG00000170584 NudC domain containing 2 5 163446526-163460140 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037384, HPA037385 Uncertain Supported Microtubules
Cytosol Expressed in all cerebral cortex: 24.7 -IRF2BP1 DKFZP434M154, IRF-2BP1 ENSG00000170604 Interferon regulatory factor 2 binding protein 1 19 45883607-45886170 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042164, HPA049480 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 13.3 -OR9K2 ENSG00000170605 Olfactory receptor, family 9, subfamily K, member 2 12 55129681-55130802 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA015808 Uncertain Not detected adipose tissue: 0.0 -HSPA4 HS24/P52, HSPH2 ENSG00000170606 Heat shock 70kDa protein 4 5 133051962-133106449 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010023, CAB025529 Uncertain Supported Nucleoplasm
Cytosol Expressed in all testis: 116.4 -FOXA3 HNF3G ENSG00000170608 Forkhead box A3 19 45863989-45873797 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level CAB015154, HPA054034 Uncertain Approved Nucleoplasm Group enriched 5 colon: 17.0;duodenum: 10.6;liver: 32.5;pancreas: 9.8;rectum: 18.2;small intestine: 14.2;stomach: 34.1 gallbladder: 3.6 -FAM71B MGC26988 ENSG00000170613 Family with sequence similarity 71, member B 5 157161846-157166264 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039478, HPA040771 Supported Tissue enriched 374 testis: 37.3 epididymis: 0.0 -SLC26A5 DFNB61, PRES ENSG00000170615 Solute carrier family 26 (anion exchanger), member 5 7 103352730-103446177 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed breast: 1.2 -COMMD5 FLJ13008, HCaRG, HT002 ENSG00000170619 COMM domain containing 5 8 144841042-144853736 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046905 Supported Nucleoplasm
Cytosol Expressed in all lymph node: 18.5 -SGCD CMD1L, DAGD, LGMD2F ENSG00000170624 Sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 5 155870344-156767788 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026969 Uncertain Mixed thyroid gland: 37.3 -GTSF1 FAM112B, FLJ32942 ENSG00000170627 Gametocyte specific factor 1 12 54455950-54473602 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038876, HPA038877 Approved Approved Nucleoplasm Tissue enriched 16 testis: 346.6 placenta: 21.1 -ZNF16 KOX9 ENSG00000170631 Zinc finger protein 16 8 144930358-144950888 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA035782, HPA061835 Uncertain Supported Nucleus
Nucleoli Expressed in all parathyroid gland: 16.0 -ARMC10 MGC3195, SVH ENSG00000170632 Armadillo repeat containing 10 7 103074881-103099764 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011036, HPA011057 Supported Supported Mitochondria Expressed in all thyroid gland: 25.5 -RNF34 FLJ21786, RIF, RIFF ENSG00000170633 Ring finger protein 34, E3 ubiquitin protein ligase 12 121400041-121430623 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA074151 Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 45.8 -ACYP2 ENSG00000170634 Acylphosphatase 2, muscle type 2 53970838-54305300 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035301 Uncertain Approved Nucleoplasm Expressed in all skeletal muscle: 73.8 -TRABD PP2447 ENSG00000170638 TraB domain containing 22 50185915-50199598 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000822 Approved Approved Nucleus
Mitochondria Expressed in all bone marrow: 38.6 -TMEM133 AD031 ENSG00000170647 Transmembrane protein 133 11 100991989-100993941 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA060528, HPA065742 Uncertain Approved Endoplasmic reticulum
Golgi apparatus Mixed placenta: 18.2 -ATF7 ATFA ENSG00000170653 Activating transcription factor 7 12 53507856-53626410 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003384 Approved Approved Nucleus
Cytosol Expressed in all endometrium: 40.1 -RASA4B ENSG00000170667 RAS p21 protein activator 4B 7 102482445-102517781 Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level Evidence at transcript level No evidence HPA043010 Uncertain Uncertain Vesicles
Cell Junctions Tissue enhanced 0 skeletal muscle: 39.7 cerebral cortex: 15.7 -SOCS6 CIS4, Cish4, HSPC060, SOCS4, SSI4, STAI4, STATI4 ENSG00000170677 Suppressor of cytokine signaling 6 18 70288901-70330200 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010189 Uncertain Approved Nuclear speckles
Cytosol Expressed in all parathyroid gland: 29.4 -MURC cavin-4, CAVIN4 ENSG00000170681 Muscle-related coiled-coil protein 9 100578079-100587906 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020973, HPA020987, HPA021021 Supported Group enriched 11 heart muscle: 31.2;skeletal muscle: 103.8 prostate: 6.1 -OR10A3 HSHTPCRX12, HTPCRX12 ENSG00000170683 Olfactory receptor, family 10, subfamily A, member 3 11 7938534-7939594 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -ZNF296 ZNF342 ENSG00000170684 Zinc finger protein 296 19 45071500-45076588 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046940, HPA049576 Uncertain Approved Nucleoplasm
Centrosome Mixed spleen: 3.9 -HOXB9 HOX2, HOX2E ENSG00000170689 Homeobox B9 17 48621159-48626356 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031463 Approved Nucleoplasm
Mitochondria Tissue enhanced 0 epididymis: 105.5 colon: 26.5 -TTLL6 FLJ35808 ENSG00000170703 Tubulin tyrosine ligase-like family member 6 17 48762235-48817214 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052397 Supported Approved Vesicles
Microtubules Tissue enhanced 0 testis: 25.9 fallopian tube: 5.8 -POLH RAD30A, XP-V ENSG00000170734 Polymerase (DNA directed), eta 6 43576150-43615660 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA006721, HPA026762 Approved Validated Nucleoplasm
Cytosol Expressed in all testis: 21.0 -SYT9 ENSG00000170743 Synaptotagmin IX 11 7238778-7469042 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 6.1;seminal vesicle: 5.1 adrenal gland: 2.8 -KCNS3 Kv9.3 ENSG00000170745 Potassium voltage-gated channel, modifier subfamily S, member 3 2 17877847-18361616 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA014864 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 lung: 35.5 skeletal muscle: 29.6 -RBMXL2 HNRNPG-T, HNRPGT ENSG00000170748 RNA binding motif protein, X-linked-like 2 11 7089027-7090900 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038912, HPA051842 Supported Tissue enriched 498 testis: 49.7 adipose tissue: 0.0 -KIF5B KNS, KNS1 ENSG00000170759 Kinesin family member 5B 10 32009010-32056431 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009846, HPA037589, HPA037590 Approved Validated Microtubule organizing center
Cytosol Expressed in all parathyroid gland: 184.2 -GPR37 EDNRBL, hET(B)R-LP, PAELR ENSG00000170775 G protein-coupled receptor 37 (endothelin receptor type B-like) 7 124745997-124765627 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042903, HPA068009 Approved Approved Nuclear membrane
Cytosol Tissue enhanced 0 cerebral cortex: 78.9;testis: 27.6 placenta: 12.7 -AKAP13 AKAP-Lbc, ARHGEF13, BRX, c-lbc, HA-3, Ht31, LBC, PROTO-LB ENSG00000170776 A kinase (PRKA) anchor protein 13 15 85380571-85749358 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019773 Approved Supported Cytosol Expressed in all endometrium: 74.2 -TPD52L3 NYD-SP25 ENSG00000170777 Tumor protein D52-like 3 9 6328375-6331900 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 2735 testis: 273.5 adipose tissue: 0.0 -CDCA4 FLJ20764, Hepp ENSG00000170779 Cell division cycle associated 4 14 105009573-105021148 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059416, HPA064971 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 bone marrow: 32.9 testis: 13.8 -OR10A4 OR10A4P ENSG00000170782 Olfactory receptor, family 10, subfamily A, member 4 11 6876625-6877619 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.1 -SDR16C5 RDH-E2, RDHE2 ENSG00000170786 Short chain dehydrogenase/reductase family 16C, member 5 8 56300010-56320776 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA025224 Supported Group enriched 6 breast: 14.9;esophagus: 36.4;lung: 40.3;skin: 73.0;small intestine: 22.1;stomach: 21.3;tonsil: 26.3 cervix: 5.6 -DYDC1 bA36D19.5, DPY30D1 ENSG00000170788 DPY30 domain containing 1 10 80336105-80356755 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA037790, HPA037791 Uncertain Tissue enriched 21 testis: 199.5 fallopian tube: 9.4 -OR10A2 OR10A2P, OST363 ENSG00000170790 Olfactory receptor, family 10, subfamily A, member 2 11 6869693-6870745 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -CHCHD7 COX23, MGC2217 ENSG00000170791 Coiled-coil-helix-coiled-coil-helix domain containing 7 8 56211686-56218798 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050783 Approved Approved Cell Junctions
Aggresome Expressed in all ovary: 61.5 -HTRA3 Prsp, Tasp ENSG00000170801 HtrA serine peptidase 3 4 8269765-8307111 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021187, HPA063810 Approved Approved Vesicles Mixed ovary: 60.7 -FOXN2 HTLF ENSG00000170802 Forkhead box N2 2 48314637-48379294 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA003485 Supported Supported Nucleus
Vesicles Expressed in all bone marrow: 36.5 -OR2AG1 OR2AG3 ENSG00000170803 Olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 11 6785038-6785988 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -LMOD2 ENSG00000170807 Leiomodin 2 (cardiac) 7 123655807-123664290 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051039 Supported Group enriched 18 heart muscle: 464.3;skeletal muscle: 316.8 esophagus: 22.0 -BFSP2 CP47, CP49, LIFL-L, phakinin ENSG00000170819 Beaded filament structural protein 2, phakinin 3 133399995-133475222 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038464, HPA062959 Supported Uncertain Plasma membrane
Cytosol Not detected lymph node: 0.4 -FSHR FSHRO, LGR1, ODG1 ENSG00000170820 Follicle stimulating hormone receptor 2 48962157-49154537 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 9 ovary: 2.5;testis: 4.3 heart muscle: 0.3 -USP32 NY-REN-60, USP10 ENSG00000170832 Ubiquitin specific peptidase 32 17 60179094-60422470 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044365 Approved Approved Golgi apparatus
Cytosol Expressed in all testis: 154.7 -CEL BSSL, MODY8 ENSG00000170835 Carboxyl ester lipase 9 133061978-133087355 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA008023, HPA052701 Supported Tissue enriched 72 pancreas: 23387.1 epididymis: 326.8 -PPM1D PP2C-DELTA, Wip1 ENSG00000170836 Protein phosphatase, Mg2+/Mn2+ dependent, 1D 17 60600183-60666280 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022277 Uncertain Approved Endoplasmic reticulum Mixed testis: 9.8 -GPR27 SREB1 ENSG00000170837 G protein-coupled receptor 27 3 71754050-71756496 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA029395 Approved Approved Nucleoplasm
Plasma membrane
Actin filaments
Cytosol Tissue enhanced 0 parathyroid gland: 45.7 cerebral cortex: 24.9 -PSG6 ENSG00000170848 Pregnancy specific beta-1-glycoprotein 6 19 42902079-42919563 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046327 Approved Tissue enriched 75 placenta: 70.1 bone marrow: 0.9 -KBTBD2 BKLHD1, DKFZP566C134 ENSG00000170852 Kelch repeat and BTB (POZ) domain containing 2 7 32868172-32894131 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021133 Uncertain Approved Nucleus
Nucleoli fibrillar center Expressed in all gallbladder: 38.7 -MINA FLJ14393, mdig, MINA53 ENSG00000170854 MYC induced nuclear antigen 3 97941818-97972457 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007603, HPA008080, CAB013458 Supported Validated Nucleus
Nucleoli Expressed in all thyroid gland: 100.5 -TRIAP1 HSPC132, MDM35, P53CSV, WF-1 ENSG00000170855 TP53 regulated inhibitor of apoptosis 1 12 120443961-120446412 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053640 Approved Approved Nucleoplasm
Mitochondria Expressed in all placenta: 40.0 -LSM3 SMX4, USS2, YLR438C ENSG00000170860 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated 3 14178358-14201119 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044966 Approved Approved Nucleus
Nucleoli Expressed in all kidney: 21.0 -KIAA0232 ENSG00000170871 KIAA0232 4 6781375-6884170 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036891, HPA036892, HPA061498 Approved Approved Cytosol Expressed in all cerebral cortex: 38.3 -MTSS1 KIAA0429, MIM, MIMA, MIMB ENSG00000170873 Metastasis suppressor 1 8 124550790-124728429 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA075540 Approved Expressed in all placenta: 51.4 -TMEM43 ARVD5, DKFZp586G1919, LUMA, MGC3222 ENSG00000170876 Transmembrane protein 43 3 14124940-14143679 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019198 Approved Expressed in all skin: 124.7 -RNF139 HRCA1, RCA1, TRC8 ENSG00000170881 Ring finger protein 139 8 124474738-124487914 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001202 Approved Expressed in all testis: 114.1 -RPS9 S9 ENSG00000170889 Ribosomal protein S9 19 54200742-54249003 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048746 Approved Expressed in all ovary: 112.5 -PLA2G1B PLA2, PLA2A, PPLA2 ENSG00000170890 Phospholipase A2, group IB (pancreas) 12 120322111-120327789 Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022329, HPA047822, HPA060803 Supported Validated Cytosol Tissue enriched 245 pancreas: 23848.8 ovary: 97.3 -CYTL1 C17, C4orf4 ENSG00000170891 Cytokine-like 1 4 5014586-5019472 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 placenta: 64.3 seminal vesicle: 18.8 -TSEN34 LENG5, SEN34, SEN34L ENSG00000170892 TSEN34 tRNA splicing endonuclease subunit 19 54189938-54194536 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041111, HPA048208 Approved Supported Nucleus Mixed fallopian tube: 36.6 -TRH ENSG00000170893 Thyrotropin-releasing hormone 3 129974305-129977938 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035595, HPA035596 Approved Group enriched 9 cervix, uterine: 31.9;endometrium: 27.4 fallopian tube: 3.3 -GSTA4 ENSG00000170899 Glutathione S-transferase alpha 4 6 52977948-52995378 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048934 Approved Expressed in all adrenal gland: 391.8 -MSANTD4 KIAA1826 ENSG00000170903 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils 11 105995623-106022403 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014411 Approved Approved Nucleus Expressed in all cerebral cortex: 27.5 -NDUFA3 B9 ENSG00000170906 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 19 54102728-54109257 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046976 Supported Expressed in all skin: 16.0 -OSCAR ENSG00000170909 Osteoclast associated, immunoglobulin-like receptor 19 54094668-54102692 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062740 Approved Nucleus
Nuclear membrane
Vesicles Tissue enhanced 0 bone marrow: 9.1;lung: 14.2 appendix: 3.4 -PAQR8 C6orf33, LMPB1, MPRB ENSG00000170915 Progestin and adipoQ receptor family member VIII 6 52361421-52407777 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA064625 Supported Golgi apparatus
Plasma membrane Mixed cerebral cortex: 65.1 -NUDT6 FGF-AS, FGF2AS, gfg, gfg-1 ENSG00000170917 Nudix (nucleoside diphosphate linked moiety X)-type motif 6 4 122888697-122922968 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039202, HPA066115 Uncertain Approved Microtubules Mixed kidney: 20.2 -OR7G3 OST085 ENSG00000170920 Olfactory receptor, family 7, subfamily G, member 3 19 9126012-9126950 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -TANC2 DKFZP564D166, FLJ10215, FLJ11824, KIAA1148, KIAA1636, rols, ROLSA ENSG00000170921 Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 17 63009556-63427699 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023274 Uncertain Approved Cytosol Tissue enhanced 0 parathyroid gland: 76.6 testis: 35.1 -OR7G2 OST260 ENSG00000170923 Olfactory receptor, family 7, subfamily G, member 2 19 9102269-9103306 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -TEX13B TGC3B, TSGA5 ENSG00000170925 Testis expressed 13B X 107980864-107982370 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA011283 Uncertain Not detected testis: 0.8 -PKHD1 ARPKD, FCYT, TIGM1 ENSG00000170927 Polycystic kidney and hepatic disease 1 (autosomal recessive) 6 51615300-52087625 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031227 Supported Group enriched 5 epididymis: 5.7;kidney: 15.2 pancreas: 1.9 -OR1M1 OR19-6 ENSG00000170929 Olfactory receptor, family 1, subfamily M, member 1 19 9093179-9094213 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected fallopian tube: 0.1 -NCBP2L ENSG00000170935 Nuclear cap binding protein subunit 2-like X 107777733-107794682 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA010664 Uncertain Tissue enhanced 0 adrenal gland: 1.9;fallopian tube: 1.6;testis: 3.9 ovary: 1.1 -DNAJC24 DPH4, JJJ3, ZCSL3 ENSG00000170946 DnaJ (Hsp40) homolog, subfamily C, member 24 11 31369840-31431849 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA020025, HPA025237 Approved Approved Cytosol Expressed in all thyroid gland: 11.4 -MBD3L1 MBD3L ENSG00000170948 Methyl-CpG binding domain protein 3-like 1 19 8832398-8843340 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA043121, HPA046753 Supported Tissue enriched 5 testis: 34.3 fallopian tube: 6.3 -ZNF160 F11, FLJ00032, HKr18, HZF5, KIAA1611, KR18 ENSG00000170949 Zinc finger protein 160 19 53066606-53103436 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023599 Uncertain Approved Nuclear speckles
Cytosol Expressed in all spleen: 38.0 -PGK2 PGK-2, PGKPS ENSG00000170950 Phosphoglycerate kinase 2 6 49785651-49787307 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045385 Uncertain Tissue enriched 782 testis: 343.6 epididymis: 0.4 -OR8B12 ENSG00000170953 Olfactory receptor, family 8, subfamily B, member 12 11 124542682-124543679 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.8 -ZNF415 ENSG00000170954 Zinc finger protein 415 19 53107879-53133077 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA005553 Approved Approved Nucleoli fibrillar center
Microtubules Mixed testis: 39.6 -PRKCDBP cavin-3, CAVIN3, HSRBC, MGC20400, SRBC ENSG00000170955 Protein kinase C, delta binding protein 11 6318946-6320647 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055136, HPA073327 Approved Approved Plasma membrane Mixed adipose tissue: 30.5 -CEACAM3 CD66d, CGM1 ENSG00000170956 Carcinoembryonic antigen-related cell adhesion molecule 3 19 41796437-41811553 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011041 Approved Tissue enriched 5 bone marrow: 28.5 appendix: 5.4 -DCDC1 ENSG00000170959 Doublecortin domain containing 1 11 30830369-31369810 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 fallopian tube: 6.4;testis: 4.3 gallbladder: 2.8 -HAS2 ENSG00000170961 Hyaluronan synthase 2 8 121612116-121641390 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052060 Approved Nuclear speckles Tissue enhanced 0 adipose tissue: 27.7 appendix: 12.9 -PDGFD IEGF, MSTP036, SCDGF-B ENSG00000170962 Platelet derived growth factor D 11 103907186-104164379 Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046183, HPA066271 Approved Approved Golgi apparatus
Vesicles Tissue enhanced 0 adrenal gland: 141.1 ovary: 96.4 -PLAC1 CT92, OOSP2L ENSG00000170965 Placenta-specific 1 X 134565838-134764322 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA063425 Supported Tissue enriched 21 placenta: 37.6 testis: 1.7 -DDI1 FLJ36017 ENSG00000170967 DNA-damage inducible 1 homolog 1 11 104036580-104039188 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 282 testis: 28.2 adipose tissue: 0.0 -S1PR1 CD363, D1S3362, edg-1, EDG1 ENSG00000170989 Sphingosine-1-phosphate receptor 1 1 101236888-101241518 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010104, HPA075568 Supported Supported Vesicles Expressed in all adipose tissue: 86.5 -HS6ST2 ENSG00000171004 Heparan sulfate 6-O-sulfotransferase 2 X 132626016-132961395 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA034625, HPA034626 Uncertain Validated Nucleoplasm Tissue enhanced 0 kidney: 14.9;ovary: 17.6 placenta: 11.9 -OR4D5 ENSG00000171014 Olfactory receptor, family 4, subfamily D, member 5 11 123939543-123940637 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA045005 Uncertain Not detected adipose tissue: 0.0 -PYGO1 ENSG00000171016 Pygopus family PHD finger 1 15 55538890-55588947 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042248 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 parathyroid gland: 29.4 thyroid gland: 12.0 -LRRC8E FLJ23420 ENSG00000171017 Leucine rich repeat containing 8 family, member E 19 7888505-7902021 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020466 Uncertain Mixed skin: 11.2 -PKIA PRKACN1 ENSG00000171033 Protein kinase (cAMP-dependent, catalytic) inhibitor alpha 8 78516139-78605267 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042791 Uncertain Tissue enhanced 0 skeletal muscle: 407.5 parathyroid gland: 121.2 -XKR6 C8orf21, C8orf5, C8orf7 ENSG00000171044 XK, Kell blood group complex subunit-related family, member 6 8 10896045-11201366 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA024828 Uncertain Mixed testis: 1.8 -TSNARE1 FLJ31164 ENSG00000171045 T-SNARE domain containing 1 8 142212080-142403240 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015890 Approved Nucleus Expressed in all skin: 29.2 -FPR2 ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R ENSG00000171049 Formyl peptide receptor 2 19 51752026-51770526 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029154 Approved Tissue enhanced 0 appendix: 71.3 spleen: 20.0 -FPR1 FMLP, FPR ENSG00000171051 Formyl peptide receptor 1 19 51745172-51804110 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046550, HPA061744 Approved Approved Nucleus
Nucleoli
Golgi apparatus Tissue enhanced 0 appendix: 181.6 bone marrow: 95.2 -PATE1 PATE ENSG00000171053 Prostate and testis expressed 1 11 125746293-125749867 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 8 epididymis: 2261.8 seminal vesicle: 294.5 -OR13H1 ENSG00000171054 Olfactory receptor, family 13, subfamily H, member 1 X 131544074-131545000 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -FEZ2 ENSG00000171055 Fasciculation and elongation protein zeta 2 (zygin II) 2 36531805-36646087 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035978 Uncertain Approved Nucleoli
Golgi apparatus
Cytosol Expressed in all cerebral cortex: 78.9 -SOX7 ENSG00000171056 SRY (sex determining region Y)-box 7 8 10723768-10730512 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA009065 Approved Approved Nuclear speckles
Golgi apparatus Tissue enhanced 0 placenta: 49.2 lung: 18.7 -C8orf74 ENSG00000171060 Chromosome 8 open reading frame 74 8 10672637-10700593 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA027986 Uncertain Uncertain Nucleoplasm Tissue enriched 42 testis: 12.4 skin: 0.2 -C11orf24 DM4E3 ENSG00000171067 Chromosome 11 open reading frame 24 11 68261335-68272001 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA012748 Uncertain Uncertain Nucleoplasm
Vesicles Expressed in all small intestine: 67.2 -ALK CD246 ENSG00000171094 Anaplastic lymphoma receptor tyrosine kinase 2 29192774-29921566 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010694 Approved Supported Plasma membrane Tissue enhanced 0 cerebral cortex: 3.5;testis: 2.3 adrenal gland: 0.9 -CCBL1 GTK, KATI ENSG00000171097 Cysteine conjugate-beta lyase, cytoplasmic 9 128832942-128882494 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021176, HPA021177, HPA027736 Approved Validated Nucleoplasm
Cytosol Mixed cerebral cortex: 17.0 -MTM1 ENSG00000171100 Myotubularin 1 X 150568619-150673322 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010008, HPA010665 Approved Supported Plasma membrane Mixed parathyroid gland: 26.8 -OBP2B hOBPIIb, LCN14 ENSG00000171102 Odorant binding protein 2B 9 133205277-133209250 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 breast: 1.8;testis: 6.8 fallopian tube: 1.4 -TRMT61B FLJ20628 ENSG00000171103 TRNA methyltransferase 61B 2 28849821-28870301 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026747, HPA026751 Supported Uncertain Cytosol Expressed in all parathyroid gland: 23.0 -INSR CD220 ENSG00000171105 Insulin receptor 19 7112255-7294034 CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036302, HPA036303 Uncertain Supported Vesicles Expressed in all spleen: 35.4 -MFN1 FLJ20693 ENSG00000171109 Mitofusin 1 3 179347692-179394931 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB033437, HPA059230 Approved Supported Mitochondria Expressed in all parathyroid gland: 20.2 -GIMAP8 DKFZp667I133, hIAN6, IAN9 ENSG00000171115 GTPase, IMAP family member 8 7 150450630-150479392 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014474, HPA017765 Supported Mixed spleen: 56.8 -HSFX1 LW-1 ENSG00000171116 Heat shock transcription factor family, X-linked 1 X 149774068-149776867 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA051700 Uncertain Mixed ovary: 4.6 -NRTN NTN ENSG00000171119 Neurturin 19 5823802-5828324 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA065260 Approved Golgi apparatus Mixed heart muscle: 4.6 -KCNMB3 KCNMB2, KCNMBL ENSG00000171121 Potassium channel subfamily M regulatory beta subunit 3 3 179236691-179267002 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA015665, HPA019185 Approved Approved Nucleus
Mitochondria Mixed placenta: 5.9 -FUT3 CD174, LE ENSG00000171124 Fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 19 5842888-5851474 Blood group antigen proteins, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046966 Supported Tissue enhanced 0 colon: 69.4;esophagus: 83.4;small intestine: 64.4 rectum: 50.3 -KCNG3 Kv6.3 ENSG00000171126 Potassium channel, voltage gated modifier subfamily G, member 3 2 42442017-42494097 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA041625 Approved Cytoplasmic bodies Tissue enhanced 0 adrenal gland: 1.2;cerebral cortex: 1.3;testis: 1.1 endometrium: 0.4 -ATP6V0E2 ATP6V0E2L, C7orf32 ENSG00000171130 ATPase, H+ transporting V0 subunit e2 7 149872968-149880698 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all cerebral cortex: 261.8 -PRKCE ENSG00000171132 Protein kinase C, epsilon 2 45651345-46187990 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001948, HPA044496, HPA054252 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 48.5 parathyroid gland: 20.3 -OR2K2 HSHTPCRH06, HTPCRH06, OR2AR1P ENSG00000171133 Olfactory receptor, family 2, subfamily K, member 2 9 111327483-111328520 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA024261 Uncertain Not detected testis: 0.3 -JAGN1 FLJ14602, GL009 ENSG00000171135 Jagunal homolog 1 3 9890554-9894349 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067610 Approved Vesicles Expressed in all epididymis: 37.2 -RLN3 H3, RXN3, ZINS4 ENSG00000171136 Relaxin 3 19 14028148-14031042 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043731 Uncertain Group enriched 6 parathyroid gland: 2.9;testis: 3.3 spleen: 0.5 -TADA3 ADA3, FLJ20221, FLJ21329, hADA3, NGG1, TADA3L ENSG00000171148 Transcriptional adaptor 3 3 9779860-9793011 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042250 Approved Supported Nucleoplasm Expressed in all testis: 71.9 -SOCS5 CIS6, Cish5, CISH6, KIAA0671, SOCS-5 ENSG00000171150 Suppressor of cytokine signaling 5 2 46698952-46763129 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA020884, CAB025510 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all ovary: 31.0 -C1GALT1C1 C1GALT2, COSMC ENSG00000171155 C1GALT1-specific chaperone 1 X 120625793-120630150 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015632 Approved Approved Cytosol Expressed in all parathyroid gland: 43.9 -C9orf16 EST00098, FLJ12823, MGC4639 ENSG00000171159 Chromosome 9 open reading frame 16 9 128160260-128163928 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020725 Uncertain Approved Microtubules Expressed in all adrenal gland: 152.1 -MORN4 bA548K23.4, C10orf83, FLJ25925, rtp ENSG00000171160 MORN repeat containing 4 10 97614553-97633500 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052718 Uncertain Expressed in all cerebral cortex: 31.9 -ZNF672 FLJ22301 ENSG00000171161 Zinc finger protein 672 1 248838210-248849517 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055779, HPA062506 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 24.3 -ZNF692 AREBP, FLJ20531, Zfp692 ENSG00000171163 Zinc finger protein 692 1 248850006-248859144 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059337, HPA062792 Uncertain Validated Nucleus
Nucleoli Expressed in all testis: 26.8 -NAIF1 bA379C10.2, C9orf90, DKFZp762G199 ENSG00000171169 Nuclear apoptosis inducing factor 1 9 128061233-128068206 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054898 Supported Nucleoplasm
Plasma membrane Mixed testis: 4.6 -RBKS DKFZp686G13268, RBSK ENSG00000171174 Ribokinase 2 27781364-27891098 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019725, HPA028285 Supported Approved Cytosol Tissue enhanced 0 adrenal gland: 34.9 kidney: 19.4 -OR2M4 HSHTPCRX18, HTPCRX18, OST710, TPCR100 ENSG00000171180 Olfactory receptor, family 2, subfamily M, member 4 1 248238929-248239864 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA051308 Uncertain Not detected cerebral cortex: 0.2 -GRIK1 GluK1, GLUR5 ENSG00000171189 Glutamate receptor, ionotropic, kainate 1 21 29536933-29940033 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014623 Uncertain Tissue enhanced 0 adrenal gland: 16.8;cerebral cortex: 9.1 prostate: 3.9 -MUC7 FLJ27047, MG2 ENSG00000171195 Mucin 7, secreted 4 70430492-70482997 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006411 Supported Tissue enriched 1474 salivary gland: 11456.2 ovary: 7.7 -PROL1 BPLP, opiorphin, PRL1 ENSG00000171199 Proline rich, lacrimal 1 4 70397882-70410194 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065711 Approved Group enriched 10 breast: 33.3;salivary gland: 19.0 epididymis: 2.5 -SMR3B P-B, PRL3, PROL3 ENSG00000171201 Submaxillary gland androgen regulated protein 3B 4 70370093-70390244 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 1618 salivary gland: 86025.2 ovary: 53.1 -TMEM126A DKFZp586C1924, OPA7 ENSG00000171202 Transmembrane protein 126A 11 85647967-85656547 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046648 Approved Approved Nucleus
Cytosol Expressed in all testis: 66.9 -TMEM126B HT007 ENSG00000171204 Transmembrane protein 126B 11 85628573-85636539 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014480, HPA019186 Uncertain Supported Mitochondria Expressed in all epididymis: 39.2 -TRIM8 GERP, RNF27 ENSG00000171206 Tripartite motif containing 8 10 102644496-102658407 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023560, HPA023561 Approved Validated Nucleoplasm
Vesicles
Cytosol Expressed in all adipose tissue: 60.7 -NETO2 FLJ10430, NEOT2 ENSG00000171208 Neuropilin (NRP) and tolloid (TLL)-like 2 16 47077703-47143997 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013180 Uncertain Approved Golgi apparatus Tissue enhanced 0 spleen: 32.0 cerebral cortex: 21.0 -CSN3 CSN10 ENSG00000171209 Casein kappa 4 70242588-70251428 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035953, HPA035954 Supported Tissue enriched 13 breast: 430.0 salivary gland: 32.3 -CLDN20 ENSG00000171217 Claudin 20 6 155264013-155276548 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed skin: 1.0 -CDC42BPG DMPK2, HSMDPKIN, kappa-200, MRCKgamma ENSG00000171219 CDC42 binding protein kinase gamma (DMPK-like) 11 64823387-64844569 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027382, HPA061836 Approved Supported Cytosol Tissue enhanced 0 skin: 35.7 parathyroid gland: 14.3 -SCAND1 RAZ1, SDP1 ENSG00000171222 SCAN domain containing 1 20 35953617-35959472 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047138 Approved Nucleus
Actin filaments
Cytosol Expressed in all duodenum: 30.2 -JUNB ENSG00000171223 Jun B proto-oncogene 19 12791496-12793315 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004464, HPA019149 Approved Validated Nucleoplasm Expressed in all adrenal gland: 322.6 -C10orf35 ENSG00000171224 Chromosome 10 open reading frame 35 10 69630251-69633599 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034591 Approved Approved Nucleus
Centrosome
Cytosol Tissue enhanced 0 cerebral cortex: 27.7 testis: 20.2 -TMEM37 PR, PR1 ENSG00000171227 Transmembrane protein 37 2 119429901-119438520 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053794 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Mixed kidney: 107.7 -UGT2B7 UGT2B9 ENSG00000171234 UDP glucuronosyltransferase 2 family, polypeptide B7 4 69051363-69112987 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045108 Uncertain Group enriched 14 kidney: 1315.4;liver: 823.8 fallopian tube: 79.1 -LRG1 LRG ENSG00000171236 Leucine-rich alpha-2-glycoprotein 1 19 4536409-4540474 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001888, HPA001889 Supported Supported Vesicles Tissue enriched 8 liver: 173.8 appendix: 21.6 -SHCBP1 FLJ22009 ENSG00000171241 SHC SH2-domain binding protein 1 16 46580554-46621626 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048876 Uncertain Approved Nuclear bodies
Microtubules Tissue enhanced 0 lymph node: 17.6 bone marrow: 16.7 -SOSTDC1 DKFZp564D206, USAG1 ENSG00000171243 Sclerostin domain containing 1 7 16461481-16530580 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lung: 57.2;stomach: 53.6 kidney: 22.9 -NPTX1 ENSG00000171246 Neuronal pentraxin I 17 80467148-80477843 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 28 cerebral cortex: 122.8 adrenal gland: 4.3 -FAM98B FLJ38426 ENSG00000171262 Family with sequence similarity 98, member B 15 38454127-38487710 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008320, HPA008502 Approved Supported Nucleoplasm
Vesicles Expressed in all parathyroid gland: 31.6 -ZNF439 DKFZp571K0837 ENSG00000171291 Zinc finger protein 439 19 11848726-11883750 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA047845 Uncertain Uncertain Nucleus Mixed parathyroid gland: 25.1 -ZNF440 FLJ37933 ENSG00000171295 Zinc finger protein 440 19 11814284-11835201 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA047845 Uncertain Uncertain Nucleus Mixed fallopian tube: 23.2 -GAA ENSG00000171298 Glucosidase, alpha; acid 17 80101556-80119879 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026970, HPA029126 Supported Expressed in all placenta: 69.4 -CANT1 SCAN-1, SHAPY ENSG00000171302 Calcium activated nucleotidase 1 17 78991717-79009867 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019627, HPA019639, HPA022818 Supported Expressed in all prostate: 110.0 -KCNK3 K2p3.1, TASK, TASK-1 ENSG00000171303 Potassium channel, two pore domain subfamily K, member 3 2 26692690-26733420 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adrenal gland: 112.3;placenta: 35.5 lung: 19.9 -ZDHHC16 APH2 ENSG00000171307 Zinc finger, DHHC-type containing 16 10 97446131-97457370 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039893, HPA040214 Uncertain Supported Nucleus
Nuclear membrane
Cytosol Expressed in all placenta: 31.3 -CHST11 C4ST, C4St-1, C4ST1, HSA269537 ENSG00000171310 Carbohydrate (chondroitin 4) sulfotransferase 11 12 104455295-104762014 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052828 Approved Approved Golgi apparatus Mixed appendix: 28.4 -EXOSC1 CGI-108, CSL4, Csl4p, hCsl4p, p13, SKI4, Ski4p ENSG00000171311 Exosome component 1 10 97436142-97446017 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038370 Approved Approved Nucleoplasm
Nuclear bodies Expressed in all epididymis: 53.9 -PGAM1 PGAM-B, PGAMA ENSG00000171314 Phosphoglycerate mutase 1 (brain) 10 97426160-97433441 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042528, HPA049237, HPA060483 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 422.5 -CHD7 CRG, FLJ20357, FLJ20361, KIAA1416 ENSG00000171316 Chromodomain helicase DNA binding protein 7 8 60678778-60868028 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053075 Supported Nucleus Mixed parathyroid gland: 14.6 -ESCO2 EFO2, RBS ENSG00000171320 Establishment of sister chromatid cohesion N-acetyltransferase 2 8 27771949-27812640 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027243, HPA053679 Supported Nucleus
Golgi apparatus Tissue enhanced 0 duodenum: 11.5 testis: 10.4 -KRT19 CK19, K19, K1CS, MGC15366 ENSG00000171345 Keratin 19, type I 17 41523617-41528308 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000031, HPA002465 Supported Supported Intermediate filaments Mixed urinary bladder: 705.5 -KRT15 CK15, K15, K1CO ENSG00000171346 Keratin 15, type I 17 41513743-41522529 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023910, HPA024554 Supported Supported Nucleoplasm
Intermediate filaments Group enriched 8 breast: 320.0;esophagus: 787.5;skin: 1012.3 prostate: 84.8 -LURAP1 C1orf190, FLJ25163, LRAP35a ENSG00000171357 Leucine rich adaptor protein 1 1 46203334-46221261 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030060, HPA030061 Uncertain Uncertain Vesicles Tissue enhanced 0 parathyroid gland: 17.4;thyroid gland: 17.5 testis: 8.9 -KRT38 KRTHA8 ENSG00000171360 Keratin 38, type I 17 41436446-41440921 Plasma proteins, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected tonsil: 0.3 -CLCN5 ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN ENSG00000171365 Chloride channel, voltage-sensitive 5 X 49922615-50099235 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000401, HPA003213 Uncertain Supported Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 epididymis: 33.2;kidney: 51.6 placenta: 9.5 -TPPP p25, p25alpha, TPPP/p25, TPPP1 ENSG00000171368 Tubulin polymerization promoting protein 5 659862-693395 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036575, HPA036576 Supported Supported Mitochondria
Cytosol Tissue enriched 10 cerebral cortex: 167.1 fallopian tube: 16.8 -KCND3 KSHIVB, Kv4.3, SCA19, SCA22 ENSG00000171385 Potassium channel, voltage gated Shal related subfamily D, member 3 1 111770662-111989155 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029452 Approved Mixed cerebral cortex: 26.8 -APLN apelin, XNPEP2 ENSG00000171388 Apelin X 129645259-129654937 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 placenta: 79.3 lung: 20.9 -KRTAP4-4 KAP4.13, KAP4.4, KRTAP4-13 ENSG00000171396 Keratin associated protein 4-4 17 41159651-41160731 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -KRT13 CK13, K13, MGC161462, MGC3781 ENSG00000171401 Keratin 13, type I 17 41500981-41505705 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000133, HPA030877 Supported Validated Intermediate filaments Tissue enriched 20 esophagus: 35268.3 tonsil: 1800.1 -XAGE3 CT12.3a, CT12.3b, GAGED4, PLAC6, pp9012, XAGE-3 ENSG00000171402 X antigen family, member 3 X 52862525-52868068 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052507, HPA059045, HPA060900 Approved Tissue enriched 165 placenta: 571.7 adipose tissue: 3.4 -KRT9 CK-9, EPPK, K9 ENSG00000171403 Keratin 9, type I 17 41565841-41572058 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skin: 2.9 adrenal gland: 0.7 -XAGE5 CT12.5, GAGED5, XAGE-5 ENSG00000171405 X antigen family, member 5 X 52812204-52818301 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA052507, HPA055941, HPA059045 Uncertain Approved Nucleoplasm
Vesicles Tissue enriched 10 testis: 2.0 skin: 0.2 -PDE7B ENSG00000171408 Phosphodiesterase 7B 6 135851696-136195574 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA023967 Uncertain Approved Nucleoplasm Mixed ovary: 16.1 -MRPL36 BRIP1, L36mt, MRP-L36, PRPL36, RPMJ ENSG00000171421 Mitochondrial ribosomal protein L36 5 1798386-1801366 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047238 Approved Supported Nuclear bodies
Mitochondria Expressed in all testis: 95.3 -ZNF581 FLJ22550, HSPC189 ENSG00000171425 Zinc finger protein 581 19 55635459-55645622 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059657 Uncertain Expressed in all ovary: 21.6 -NAT1 AAC1 ENSG00000171428 N-acetyltransferase 1 (arylamine N-acetyltransferase) 8 18170477-18223689 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017782, HPA043704 Approved Mixed epididymis: 18.3 -KRT20 CK20, K20, MGC35423 ENSG00000171431 Keratin 20, type I 17 40875941-40885227 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000032, HPA024309, HPA024684, HPA027236 Supported Approved Cytosol Tissue enhanced 0 colon: 361.8;duodenum: 259.3;rectum: 299.7;small intestine: 509.8 stomach: 83.3 -GLOD5 ENSG00000171433 Glyoxalase domain containing 5 X 48761750-48773648 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010667 Uncertain Uncertain Mitochondria Tissue enhanced 0 duodenum: 11.1;kidney: 10.9;small intestine: 10.9 epididymis: 6.7 -KSR2 FLJ25965 ENSG00000171435 Kinase suppressor of ras 2 12 117453012-117968983 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035536 Approved Tissue enhanced 0 cerebral cortex: 4.1 adrenal gland: 1.2 -ZNF524 MGC23143 ENSG00000171443 Zinc finger protein 524 19 55600022-55603138 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA050981 Uncertain Approved Nucleus Expressed in all spleen: 16.0 -MCC ENSG00000171444 Mutated in colorectal cancers 5 113022099-113488830 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037390, HPA037391 Approved Approved Supported Nucleoplasm Tissue enhanced 0 ovary: 87.2;parathyroid gland: 66.6 skin: 25.2 -KRT27 KRT25C ENSG00000171446 Keratin 27, type I 17 40776808-40782534 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055114 Supported Tissue enhanced 0 breast: 1.3 skin: 0.5 -ZBTB26 ZNF481 ENSG00000171448 Zinc finger and BTB domain containing 26 9 122915566-122931500 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021444 Uncertain Mixed testis: 18.1 -CDK5R2 NCK5AI, P39, p39nck5ai ENSG00000171450 Cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2 218959655-218962162 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 10 cerebral cortex: 52.3 adrenal gland: 5.1 -DSEL C18orf4, FLJ11477, NCAG1 ENSG00000171451 Dermatan sulfate epimerase-like 18 67506582-67516980 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA060942 Approved Nucleoplasm
Plasma membrane Mixed cerebral cortex: 5.3 -POLR1C RPA39, RPA40, RPA5, RPAC1 ENSG00000171453 Polymerase (RNA) I polypeptide C, 30kDa 6 43509702-43529585 Disease related genes, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031010 Supported Nucleus Expressed in all testis: 34.4 -ASXL1 KIAA0978 ENSG00000171456 Additional sex combs like transcriptional regulator 1 20 32358344-32439319 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064156 Approved Nucleus
Nucleoli Expressed in all testis: 68.2 -OR1L6 OR1L7 ENSG00000171459 Olfactory receptor, family 1, subfamily L, member 6 9 122749740-122750783 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -DLK2 EGFL9, MGC2487 ENSG00000171462 Delta-like 2 homolog (Drosophila) 6 43450352-43456632 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA061223, HPA068672 Uncertain Approved Nucleus Tissue enhanced 0 skin: 14.5 prostate: 8.1 -ZNF562 FLJ20079 ENSG00000171466 Zinc finger protein 562 19 9641808-9675086 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055332, HPA062397 Uncertain Approved Nucleoplasm Expressed in all esophagus: 19.1 -ZNF318 HRIHFB2436, ZFP318 ENSG00000171467 Zinc finger protein 318 6 43307134-43369478 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027022, HPA027031 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 49.4 -ZNF561 MGC45408 ENSG00000171469 Zinc finger protein 561 19 9604680-9621399 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055332, HPA062397 Uncertain Approved Nucleoplasm Expressed in all smooth muscle: 37.6 -WIPF2 WICH, WIRE ENSG00000171475 WAS/WASL interacting protein family, member 2 17 40219304-40284136 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024000, HPA024001, HPA024467 Supported Supported Nucleoplasm Expressed in all cerebral cortex: 32.5 -HOPX HOP, LAGY, NECC1, OB1, SMAP31 ENSG00000171476 HOP homeobox 4 56647988-56681899 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018632, HPA030180 Supported Tissue enhanced 0 epididymis: 647.0;skin: 840.3 esophagus: 527.6 -SPACA5B ENSG00000171478 Sperm acrosome associated 5B X 48130657-48132613 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044747, HPA047149 Supported Tissue enriched 148 testis: 16.4 fallopian tube: 0.1 -OR1L3 OR9-D ENSG00000171481 Olfactory receptor, family 1, subfamily L, member 3 9 122675130-122676104 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA058878 Uncertain Not detected cerebral cortex: 0.1 -OR1B1 OR9-B ENSG00000171484 Olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 9 122628579-122629535 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA058654 Uncertain Not detected adipose tissue: 0.0 -NLRP5 CLR19.8, MATER, NALP5, PAN11, PYPAF8 ENSG00000171487 NLR family, pyrin domain containing 5 19 55999726-56061813 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056271 Uncertain Tissue enriched 50 parathyroid gland: 22.5 testis: 0.4 -LRRC8C AD158 ENSG00000171488 Leucine rich repeat containing 8 family, member C 1 89633072-89769903 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029347 Uncertain Approved Golgi apparatus Mixed smooth muscle: 22.4 -SPACA5 dJ54B20.3, LYC5, LYZL5, PNPK6288, SLLP2, UNQ6288 ENSG00000171489 Sperm acrosome associated 5 X 48004336-48009729 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044747, HPA047149 Supported Group enriched 6 epididymis: 2.7;testis: 13.7 thyroid gland: 1.4 -RSL1D1 CSIG, DKFZP564M182, L12, PBK1, UTP30 ENSG00000171490 Ribosomal L1 domain containing 1 16 11833850-11851585 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043483 Supported Validated Nucleoli Expressed in all ovary: 145.4 -LRRC8D FLJ10470, LRRC5 ENSG00000171492 Leucine rich repeat containing 8 family, member D 1 89821014-89936611 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014745 Approved Nucleoplasm
Mitochondria Expressed in all cerebral cortex: 36.0 -MROH2B DKFZp781F0822, FLJ40243, HEATR7B2 ENSG00000171495 Maestro heat-like repeat family member 2B 5 40998017-41071342 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA059457 Supported Tissue enriched 251 testis: 41.6 smooth muscle: 0.1 -OR1L8 ENSG00000171496 Olfactory receptor, family 1, subfamily L, member 8 9 122567548-122568477 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 spleen: 1.2;testis: 1.3 fallopian tube: 0.4 -PPID CYP-40 ENSG00000171497 Peptidylprolyl isomerase D 4 158709134-158723396 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019520, HPA019692 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all liver: 71.3 -OR1N2 ENSG00000171501 Olfactory receptor, family 1, subfamily N, member 2 9 122553112-122555173 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -COL24A1 ENSG00000171502 Collagen, type XXIV, alpha 1 1 85729233-86156943 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed cervix: 3.4 -ETFDH ETFQO ENSG00000171503 Electron-transferring-flavoprotein dehydrogenase 4 158672125-158709623 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041978 Supported Expressed in all liver: 99.6 -OR1N1 OR1-26, OR1N3 ENSG00000171505 Olfactory receptor, family 1, subfamily N, member 1 9 122526358-122527296 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.1 -RXFP1 LGR7, RXFPR1 ENSG00000171509 Relaxin/insulin-like family peptide receptor 1 4 158315311-158653372 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA027067 Approved Tissue enhanced 0 cerebral cortex: 21.7;endometrium: 10.1 adrenal gland: 5.7 -LPAR3 Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3 ENSG00000171517 Lysophosphatidic acid receptor 3 1 84811602-84893213 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA013421 Uncertain Supported Plasma membrane Tissue enhanced 0 fallopian tube: 66.2 prostate: 21.5 -PTGER4 EP4 ENSG00000171522 Prostaglandin E receptor 4 (subtype EP4) 5 40679498-40693735 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA011226, HPA012756 Approved Expressed in all bone marrow: 48.1 -TBCA ENSG00000171530 Tubulin folding cofactor A 5 77691166-77868780 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036487 Approved Supported Nucleoli
Microtubules Expressed in all adrenal gland: 307.1 -NEUROD2 bHLHa1, NDRF ENSG00000171532 Neuronal differentiation 2 17 39603536-39609777 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 146 cerebral cortex: 14.9 stomach: 0.1 -MAP6 FLJ41346, KIAA1878, MAP6-N, STOP ENSG00000171533 Microtubule-associated protein 6 11 75586918-75669120 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015442, CAB022600, HPA039061, HPA039062 Supported Uncertain Plasma membrane Tissue enhanced 0 cerebral cortex: 68.4;fallopian tube: 64.7 parathyroid gland: 51.7 -OTP ENSG00000171540 Orthopedia homeobox 5 77628712-77639688 Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level HPA039365 Uncertain Not detected testis: 0.1 -ECEL1 DINE, XCE ENSG00000171551 Endothelin converting enzyme-like 1 2 232479827-232487828 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067560 Approved Nucleoplasm
Nuclear membrane
Nucleoli Tissue enriched 24 ovary: 111.9 spleen: 4.6 -BCL2L1 Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52 ENSG00000171552 BCL2-like 1 20 31664452-31723989 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035734, CAB072801 Approved Approved Mitochondria Expressed in all gallbladder: 100.9 -FGG ENSG00000171557 Fibrinogen gamma chain 4 154604134-154612967 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027529, CAB033120 Supported Tissue enriched 115 liver: 8684.7 lung: 75.3 -FGA ENSG00000171560 Fibrinogen alpha chain 4 154583126-154590766 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016776, HPA051370, HPA064755 Supported Tissue enriched 246 liver: 9252.8 stomach: 37.6 -OR2AT4 ENSG00000171561 Olfactory receptor, family 2, subfamily AT, member 4 11 75088713-75089754 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060357 Uncertain Not detected adipose tissue: 0.0 -FGB ENSG00000171564 Fibrinogen beta chain 4 154562956-154571086 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001900, HPA001901, CAB008624 Supported Tissue enriched 558 liver: 9991.3 kidney: 17.9 -PLRG1 Cwc1, PRL1, Prp46, PRPF46, TANGO4 ENSG00000171566 Pleiotropic regulator 1 4 154535006-154550435 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035931, HPA035932, HPA061486 Supported Validated Nuclear membrane
Nuclear speckles Expressed in all parathyroid gland: 65.7 -ZNF584 FLJ39899 ENSG00000171574 Zinc finger protein 584 19 58401504-58418327 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043408, HPA048075 Uncertain Approved Nuclear speckles Mixed fallopian tube: 9.9 -DSCAM CHD2-42, CHD2-52 ENSG00000171587 Down syndrome cell adhesion molecule 21 40010999-40847139 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019324 Supported Approved Nucleoplasm
Cytosol Tissue enriched 11 cerebral cortex: 12.5 spleen: 1.1 -DNAI2 CILD9, DIC2 ENSG00000171595 Dynein, axonemal, intermediate chain 2 17 74274247-74314884 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB006245, HPA050565 Supported Group enriched 8 fallopian tube: 47.5;testis: 27.7 lung: 4.7 -NMUR1 FM-3, GPC-R, GPR66, NMU1R ENSG00000171596 Neuromedin U receptor 1 2 231523160-231530495 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027895 Uncertain Mixed adipose tissue: 5.5 -CLSTN1 CDHR12, CSTN1, KIAA0911 ENSG00000171603 Calsyntenin 1 1 9729026-9824526 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012412 Approved Expressed in all cerebral cortex: 382.9 -CXXC5 HSPC195, RINF, WID ENSG00000171604 CXXC finger protein 5 5 139647299-139683882 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036508, HPA058148 Approved Validated Nucleoplasm
Cytosol Expressed in all cerebral cortex: 99.5 -ZNF274 ZKSCAN19, ZSCAN51 ENSG00000171606 Zinc finger protein 274 19 58183029-58213562 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028880 Uncertain Supported Nucleus
Centrosome Expressed in all parathyroid gland: 39.6 -PIK3CD p110D ENSG00000171608 Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1 9651732-9729114 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015420, HPA044953 Approved Approved Vesicles
Cytokinetic bridge Tissue enhanced 0 lymph node: 57.2 spleen: 52.1 -PTCRA PT-ALPHA, PTA ENSG00000171611 Pre T-cell antigen receptor alpha 6 42915989-42925835 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 3.2;spleen: 4.9 tonsil: 2.1 -SLC25A33 BMSC-MCP, MGC4399, PNC1 ENSG00000171612 Solute carrier family 25 (pyrimidine nucleotide carrier), member 33 1 9539482-9585179 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049982 Uncertain Mixed testis: 22.0 -ENC1 ENC-1, KLHL37, NRPB, PIG10, TP53I10 ENSG00000171617 Ectodermal-neural cortex 1 (with BTB domain) 5 74627406-74641424 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA078061 Uncertain Plasma membrane
Cytoplasmic bodies Tissue enriched 15 cerebral cortex: 462.7 gallbladder: 30.9 -SPSB1 SSB-1 ENSG00000171621 SplA/ryanodine receptor domain and SOCS box containing 1 1 9292880-9369532 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed adipose tissue: 61.7 -P2RY6 P2Y6 ENSG00000171631 Pyrimidinergic receptor P2Y, G-protein coupled, 6 11 73264505-73298617 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB022740 Uncertain Tissue enhanced 0 placenta: 16.8;spleen: 36.2 appendix: 11.0 -BPTF FAC1, FALZ, NURF301 ENSG00000171634 Bromodomain PHD finger transcription factor 17 67825524-67984378 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029069, HPA048289 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 66.3 -S100Z Gm625, S100-zeta ENSG00000171643 S100 calcium binding protein Z 5 76850001-76921650 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed spleen: 3.4 -ZIK1 ZNF762 ENSG00000171649 Zinc finger protein interacting with K protein 1 19 57578456-57593777 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059975 Uncertain Approved Intermediate filaments Mixed parathyroid gland: 12.0 -GPR82 ENSG00000171657 G protein-coupled receptor 82 X 41724155-41730135 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035914 Approved Tissue enhanced 0 tonsil: 6.7 lymph node: 3.7 -GPR34 ENSG00000171659 G protein-coupled receptor 34 X 41688973-41697277 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA010668, CAB025490 Uncertain Uncertain Nucleus
Cytosol Mixed placenta: 60.4 -PLEKHG5 GEF720, KIAA0720, Syx, Tech ENSG00000171680 Pleckstrin homology domain containing, family G (with RhoGef domain) member 5 1 6466092-6520061 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049570 Uncertain Approved Nucleus Tissue enhanced 0 skin: 111.2 spleen: 35.3 -ATF7IP FLJ10688, p621 ENSG00000171681 Activating transcription factor 7 interacting protein 12 14365632-14502935 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016578, HPA023505 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all testis: 61.7 -LKAAEAR1 C20orf201 ENSG00000171695 LKAAEAR motif containing 1 20 64083380-64084359 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056463 Uncertain Tissue enhanced 0 testis: 2.8 cerebral cortex: 0.8 -RGS19 GAIP, RGSGAIP ENSG00000171700 Regulator of G-protein signaling 19 20 64073181-64079988 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA070250 Approved Nucleoli
Vesicles Tissue enhanced 0 spleen: 54.7 lymph node: 40.4 -TCEA2 TFIIS ENSG00000171703 Transcription elongation factor A (SII), 2 20 64049836-64072347 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043836 Approved Supported Nucleoplasm
Centrosome Expressed in all cerebral cortex: 74.0 -DEFB4A DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1 ENSG00000171711 Defensin, beta 4A 8 7894629-7896711 Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 8 esophagus: 6.0;gallbladder: 10.4;tonsil: 12.8 cervix: 1.1 -ANO5 GDD1, LGMD2L, TMEM16E ENSG00000171714 Anoctamin 5 11 22193176-22283357 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058857 Uncertain Tissue enhanced 0 parathyroid gland: 55.2 skeletal muscle: 23.6 -HDAC3 HD3, RPD3, RPD3-2 ENSG00000171720 Histone deacetylase 3 5 141620876-141636870 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005583, HPA052052 Supported Supported Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 51.1 -C1orf111 ENSG00000171722 Chromosome 1 open reading frame 111 1 162373203-162376870 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 14 testis: 60.1 adrenal gland: 4.2 -GPHN KIAA1385 ENSG00000171723 Gephyrin 14 66507407-67181803 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003116, CAB004419, HPA024694 Supported Uncertain Cytoplasmic bodies Expressed in all cerebral cortex: 30.5 -VAT1L KIAA1576 ENSG00000171724 Vesicle amine transport 1-like 16 77788530-77980107 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044061, CAB046032 Approved Approved Cytosol Group enriched 6 adrenal gland: 91.0;cerebral cortex: 38.9 heart muscle: 10.6 -TMEM51 C1orf72, FLJ10199 ENSG00000171729 Transmembrane protein 51 1 15152532-15220480 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014547, HPA019441 Approved Approved Nucleoplasm
Cytosol Mixed gallbladder: 33.5 -CAMTA1 KIAA0833 ENSG00000171735 Calmodulin binding transcription activator 1 1 6785324-7769706 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036342, HPA036343 Approved Supported Nucleoli
Cytosol Expressed in all epididymis: 98.1 -LGALS4 GAL4 ENSG00000171747 Lectin, galactoside-binding, soluble, 4 19 38801671-38813364 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025653, HPA031184, HPA031185, HPA031186 Supported Tissue enhanced 0 colon: 749.2;duodenum: 541.6;rectum: 652.0;small intestine: 503.3 gallbladder: 139.4 -LRRC34 MGC27085 ENSG00000171757 Leucine rich repeat containing 34 3 169793428-169812986 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035747, HPA058105 Approved Approved Cell Junctions
Microtubules
Cytokinetic bridge Group enriched 8 fallopian tube: 12.2;testis: 26.8 cerebral cortex: 2.3 -PAH PH ENSG00000171759 Phenylalanine hydroxylase 12 102836885-102958410 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028407, HPA031642 Supported Approved Endoplasmic reticulum
Vesicles Tissue enhanced 0 kidney: 500.3;liver: 720.9 gallbladder: 126.2 -SPATA5L1 FLJ12286, MGC5347 ENSG00000171763 Spermatogenesis associated 5-like 1 15 45402331-45421419 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043679 Uncertain Approved Nucleus
Nucleoli Mixed thyroid gland: 8.9 -GATM AGAT ENSG00000171766 Glycine amidinotransferase (L-arginine:glycine amidinotransferase) 15 45361124-45402327 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026077 Supported Supported Mitochondria Group enriched 6 kidney: 1889.7;liver: 1289.2;pancreas: 573.5 ovary: 194.5 -SYCE1 bA108K14.6, C10orf94, CT76 ENSG00000171772 Synaptonemal complex central element protein 1 10 133553901-133569835 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040208 Supported Uncertain Nucleoplasm
Cytosol Tissue enriched 6 testis: 82.3 placenta: 13.5 -NXNL1 RDCVF, TXNL6 ENSG00000171773 Nucleoredoxin-like 1 19 17455425-17460954 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042010 Approved Tissue enhanced 0 adipose tissue: 2.0 skin: 1.0 -RASGRP4 ENSG00000171777 RAS guanyl releasing protein 4 19 38409051-38426305 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 13.1 appendix: 9.0 -NHLH1 bHLHa35, HEN1, NSCL, NSCL1 ENSG00000171786 Nescient helix loop helix 1 1 160367067-160372848 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB033854 Uncertain Not detected skin: 0.8 -SLFNL1 FLJ23878 ENSG00000171790 Schlafen-like 1 1 41015597-41023237 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA054956 Approved Cytosol Tissue enriched 16 testis: 47.7 lung: 3.0 -BCL2 Bcl-2, PPP1R50 ENSG00000171791 B-cell CLL/lymphoma 2 18 63123346-63320128 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000003, HPA055295 Supported Supported Nucleoplasm
Nuclear membrane Tissue enhanced 0 thyroid gland: 69.2 parathyroid gland: 34.6 -RHNO1 C12orf32, HKMT1188, MGC13204, RHINO ENSG00000171792 RAD9-HUS1-RAD1 interacting nuclear orphan 1 12 2876258-2889523 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all thyroid gland: 28.3 -CTPS1 CTPS ENSG00000171793 CTP synthase 1 1 40979335-41012565 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017111, HPA051322 Approved Supported Actin filaments
Cytosol Expressed in all smooth muscle: 79.3 -UTF1 ENSG00000171794 Undifferentiated embryonic cell transcription factor 1 10 133230274-133231558 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 11 testis: 1.4 spleen: 0.1 -KNDC1 bB439H18.3, C10orf23, FLJ25027, KIAA1768, RASGEF2 ENSG00000171798 Kinase non-catalytic C-lobe domain (KIND) containing 1 10 133160447-133226412 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039624 Uncertain Tissue enhanced 0 cerebral cortex: 19.5;fallopian tube: 10.5 adrenal gland: 6.4 -WDR87 NYD-SP11 ENSG00000171804 WD repeat domain 87 19 37884823-37906677 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 147 testis: 30.5 thyroid gland: 0.2 -METTL18 AsTP2, C1orf156, HPM1, MGC9084 ENSG00000171806 Methyltransferase like 18 1 169792529-169794966 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035314 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 parathyroid gland: 43.7 lymph node: 15.5 -CFAP46 bA288G11.4, bA288G11.5, bB137A17.2, bB137A17.3, C10orf123, C10orf124, C10orf92, C10orf93, DKFZp434A1721, FLJ25954, TTC40 ENSG00000171811 Cilia and flagella associated protein 46 10 132808392-132942823 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037786, HPA038034, HPA038867, HPA038868 Uncertain Tissue enhanced 0 fallopian tube: 8.4;testis: 17.6 skeletal muscle: 5.8 -COL8A2 FECD, FECD1, PPCD, PPCD2 ENSG00000171812 Collagen, type VIII, alpha 2 1 36095236-36125220 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049788 Uncertain Uncertain Golgi apparatus Mixed placenta: 18.1 -PWWP2B bA432J24.1, FLJ46823, PWWP2 ENSG00000171813 PWWP domain containing 2B 10 132397168-132417863 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038056, HPA038502 Validated Nucleoplasm Mixed spleen: 16.8 -PCDHB1 PCDH-BETA1 ENSG00000171815 Protocadherin beta 1 5 141051135-141059344 Predicted membrane proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level HPA053921 Uncertain Not detected testis: 0.9 -ZNF540 DKFZp547B0714 ENSG00000171817 Zinc finger protein 540 19 37551406-37614097 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA003444 Supported Supported Nucleoplasm
Vesicles
Cytosol Mixed thyroid gland: 13.2 -ANGPTL7 AngX, CDT6 ENSG00000171819 Angiopoietin-like 7 1 11189341-11195981 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 seminal vesicle: 9.2 heart muscle: 6.1 -FBXL14 Fbl14, MGC40195 ENSG00000171823 F-box and leucine-rich repeat protein 14 12 1565993-1594165 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053889 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all cerebral cortex: 15.3 -EXOSC10 p2, p3, p4, PM-Scl, PM/Scl-100, PMSCL2, RRP6, Rrp6p ENSG00000171824 Exosome component 10 1 11066618-11099881 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028470, HPA028484, CAB037141 Supported Supported Nucleus
Nucleoli
Cytosol Expressed in all endometrium: 46.5 -ZNF570 FLJ30791 ENSG00000171827 Zinc finger protein 570 19 37467585-37488652 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028881 Uncertain Approved Nucleoplasm Mixed testis: 10.7 -NINJ2 ENSG00000171840 Ninjurin 2 12 564296-663779 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058980 Approved Endoplasmic reticulum Tissue enhanced 0 lung: 55.8 bone marrow: 24.0 -MLLT3 AF-9, AF9, YEATS3 ENSG00000171843 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3 9 20341665-20622543 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001824 Approved Approved Nucleoplasm
Cytosol Mixed thyroid gland: 40.4 -FAM90A1 FLJ10408 ENSG00000171847 Family with sequence similarity 90, member A1 12 8221260-8227618 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 epididymis: 9.4 cerebral cortex: 5.0 -RRM2 ENSG00000171848 Ribonucleotide reductase M2 2 10122328-10131419 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056994 Approved Supported Cytosol Mixed lymph node: 47.8 -TRAPPC12 CGI-87, TTC-15, TTC15 ENSG00000171853 Trafficking protein particle complex 12 2 3379675-3485094 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034799 Uncertain Expressed in all testis: 48.8 -IFNB1 IFB, IFF, IFNB ENSG00000171855 Interferon, beta 1, fibroblast 9 21077105-21077963 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB009386 Uncertain Not detected bone marrow: 0.3 -RPS21 S21 ENSG00000171858 Ribosomal protein S21 20 62387116-62388520 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003371 Approved Validated Endoplasmic reticulum
Cytosol Expressed in all ovary: 2347.4 -C3AR1 AZ3B, C3AR ENSG00000171860 Complement component 3a receptor 1 12 8058302-8066471 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB009405 Supported Tissue enhanced 0 appendix: 88.4 placenta: 49.2 -RNMTL1 FLJ10581, HC90, MRM3, RMTL1 ENSG00000171861 RNA methyltransferase like 1 17 782273-792509 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022534, HPA023031, HPA023292 Supported Supported Mitochondria Expressed in all testis: 31.5 -PTEN BZS, MHAM, MMAC1, PTEN1, TEP1 ENSG00000171862 Phosphatase and tensin homolog 10 87863113-87971930 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004076, HPA031335 Uncertain Supported Nucleoplasm
Cytosol Mixed testis: 59.0 -RPS7 S7 ENSG00000171863 Ribosomal protein S7 2 3575205-3580919 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056586 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all ovary: 2607.1 -PRND dJ1068H6.4, DOPPEL, DPL, PrPLP ENSG00000171864 Prion protein 2 (dublet) 20 4721910-4728460 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043373 Supported Tissue enriched 22 testis: 136.1 endometrium: 6.0 -RNASEH1 ENSG00000171865 Ribonuclease H1 2 3544793-3558616 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043037 Uncertain Expressed in all smooth muscle: 10.9 -PRNP AltPrP, CD230, CJD, GSS, PRIP, PRP ENSG00000171867 Prion protein 20 4686236-4701590 CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042754, HPA043398 Supported Approved Nuclear membrane
Vesicles
Cytosol Expressed in all cerebral cortex: 621.3 -KLF17 FLJ40160, Zfp393, ZNF393 ENSG00000171872 Kruppel-like factor 17 1 44118850-44135140 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA024629 Approved Tissue enhanced 0 testis: 8.1 smooth muscle: 1.7 -ADRA1D ADRA1, ADRA1A, ADRA1R ENSG00000171873 Adrenoceptor alpha 1D 20 4220631-4249074 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA038789 Uncertain Tissue enhanced 0 cervix, uterine: 4.3;prostate: 4.2 seminal vesicle: 2.5 -FRMD5 MGC14161 ENSG00000171877 FERM domain containing 5 15 43870761-44195252 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011746, HPA013961 Uncertain Uncertain Golgi apparatus
Centrosome Group enriched 6 adrenal gland: 7.1;cerebral cortex: 20.1;heart muscle: 7.1;testis: 5.5 fallopian tube: 1.6 -AQP4 MIWC ENSG00000171885 Aquaporin 4 18 26852038-26865818 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005079, HPA014784, CAB058689 Supported Supported Supported Plasma membrane
Cell Junctions Group enriched 17 cerebral cortex: 631.8;lung: 172.2 thyroid gland: 24.3 -CYP4F11 ENSG00000171903 Cytochrome P450, family 4, subfamily F, polypeptide 11 19 15912367-15934867 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017265, CAB033648, HPA058960 Supported Tissue enhanced 0 gallbladder: 29.6;liver: 32.7;small intestine: 26.8 epididymis: 19.8 -TLN2 ILWEQ, KIAA0320 ENSG00000171914 Talin 2 15 62390526-62844631 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017194 Approved Supported Focal adhesion sites
Cytosol Tissue enhanced 0 cerebral cortex: 41.0;kidney: 40.3 thyroid gland: 21.5 -LGALS9C ENSG00000171916 Lectin, galactoside-binding, soluble, 9C 17 18476737-18494945 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046876, HPA047218 Approved Approved Cytosol Tissue enhanced 0 gallbladder: 9.9;rectum: 10.3;stomach: 19.9 colon: 5.5 -TVP23B CGI-148, FAM18B, FAM18B1, YDR084C ENSG00000171928 Trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 17 18780995-18806714 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA019585, HPA065603 Uncertain Approved Golgi apparatus Expressed in all thyroid gland: 78.3 -FBXW10 C17orf1, C17orf1A, Fbw10, HREP, SM2SH2 ENSG00000171931 F-box and WD repeat domain containing 10 17 18744024-18779349 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047457 Approved Nucleoplasm Tissue enriched 20 testis: 17.4 epididymis: 0.8 -OR10H3 ENSG00000171936 Olfactory receptor, family 10, subfamily H, member 3 19 15741393-15742343 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -ZNF217 ZABC1 ENSG00000171940 Zinc finger protein 217 20 53567065-53609907 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051857 Approved Validated Nuclear speckles Mixed testis: 43.7 -OR10H2 ENSG00000171942 Olfactory receptor, family 10, subfamily H, member 2 19 15728020-15729060 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -SRGAP2C SRGAP2P1 ENSG00000171943 SLIT-ROBO Rho GTPase activating protein 2C 1 121184810-121392822 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 parathyroid gland: 33.7 skin: 18.2 -OR52A5 ENSG00000171944 Olfactory receptor, family 52, subfamily A, member 5 11 5131692-5132642 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected bone marrow: 0.1 -SCG2 CHGC, SgII, SN ENSG00000171951 Secretogranin II 2 223596940-223602503 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002519, HPA011893 Approved Supported Group enriched 7 adrenal gland: 449.0;cerebral cortex: 232.7 duodenum: 46.3 -ATPAF2 ATP12, Atp12p, LP3663, MGC29736 ENSG00000171953 ATP synthase mitochondrial F1 complex assembly factor 2 17 17977409-18039209 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023329, HPA059422 Supported Validated Cytosol Expressed in all parathyroid gland: 23.1 -CYP4F22 FLJ39501 ENSG00000171954 Cytochrome P450, family 4, subfamily F, polypeptide 22 19 15508493-15552317 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058960 Uncertain Tissue enhanced 0 esophagus: 14.1;skin: 34.3 seminal vesicle: 9.0 -FOXB1 FKH5, HFKH-5 ENSG00000171956 Forkhead box B1 15 60004222-60061730 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA073369 Approved Nucleoplasm
Mitochondria Not detected testis: 0.7 -PPIH CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP ENSG00000171960 Peptidylprolyl isomerase H (cyclophilin H) 1 42658425-42676758 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059019 Approved Expressed in all testis: 67.6 -DRC3 CFAP134, DKFZP586M1120, LRRC48 ENSG00000171962 Dynein regulatory complex subunit 3 17 17972813-18016889 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036040, HPA036041 Approved Tissue enhanced 0 fallopian tube: 98.0 testis: 21.8 -ZNF57 ZNF424 ENSG00000171970 Zinc finger protein 57 19 2900898-2918476 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA061915 Approved Nucleoli Tissue enriched 5 testis: 58.4 skin: 11.6 -C20orf196 FLJ25067 ENSG00000171984 Chromosome 20 open reading frame 196 20 5750393-5863912 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040749 Approved Approved Endoplasmic reticulum
Golgi apparatus
Vesicles Mixed lymph node: 18.8 -C11orf40 NOV1 ENSG00000171987 Chromosome 11 open reading frame 40 11 4571423-4577820 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.2 -JMJD1C DKFZp761F0118, FLJ14374, KIAA1380, TRIP8 ENSG00000171988 Jumonji domain containing 1C 10 63167221-63521850 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056175, HPA066195 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 52.5 -LDHAL6B LDH6B, LDHAL6, LDHL ENSG00000171989 Lactate dehydrogenase A-like 6B 15 59206823-59208515 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053962 Supported Tissue enriched 165 testis: 76.1 gallbladder: 0.4 -SYNPO KIAA1029 ENSG00000171992 Synaptopodin 5 150601080-150659220 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033265, HPA034631, CAB037325 Approved Approved Nucleoplasm
Actin filaments
Cytosol Tissue enhanced 0 skeletal muscle: 446.7 heart muscle: 241.1 -ZNF556 FLJ11637 ENSG00000172000 Zinc finger protein 556 19 2867335-2883445 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060593 Approved Nucleus Tissue enhanced 0 fallopian tube: 3.3;ovary: 6.5 testis: 1.3 -MAL ENSG00000172005 Mal, T-cell differentiation protein 2 95025677-95053996 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA065691 Approved Centrosome Tissue enriched 7 esophagus: 2459.4 tonsil: 328.8 -ZNF554 FLJ34817 ENSG00000172006 Zinc finger protein 554 19 2819874-2835773 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA060247, HPA063358 Uncertain Supported Nucleoplasm
Nucleoli Mixed cerebral cortex: 7.5 -RAB33B DKFZP434G099 ENSG00000172007 RAB33B, member RAS oncogene family 4 139453232-139476609 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048367 Uncertain Expressed in all endometrium: 13.0 -THOP1 ENSG00000172009 Thimet oligopeptidase 1 19 2785460-2815807 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025497, HPA035262 Uncertain Supported Cytosol Expressed in all testis: 36.2 -ANKRD20A4 ENSG00000172014 Ankyrin repeat domain 20 family, member A4 9 64369394-64413142 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA043239, HPA047112, HPA047167, HPA047766, HPA051753 Uncertain Mixed testis: 1.3 -REG3A HIP, PAP, PAP1, PBCGF, REG-III, REG3 ENSG00000172016 Regenerating islet-derived 3 alpha 2 79157003-79159753 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047894, HPA048334, HPA060705 Supported Approved Cytosol Group enriched 57 duodenum: 5795.6;small intestine: 8246.6 stomach: 122.9 -GAP43 B-50, PP46 ENSG00000172020 Growth associated protein 43 3 115623324-115721490 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004417, HPA013392, HPA015600 Supported Validated Plasma membrane Tissue enriched 37 cerebral cortex: 346.9 appendix: 9.4 -REG1B PSPS2, REGH, REGI-BETA, REGL ENSG00000172023 Regenerating islet-derived 1 beta 2 79085030-79088019 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045549, HPA045579 Supported Tissue enhanced 0 duodenum: 755.9;small intestine: 443.6 pancreas: 181.5 -EPHX4 ABHD7, EPHXRP, FLJ90341 ENSG00000172031 Epoxide hydrolase 4 1 92029982-92063536 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035067 Uncertain Approved Vesicles Tissue enhanced 0 cerebral cortex: 14.6 thyroid gland: 3.0 -LAMB2 LAMS ENSG00000172037 Laminin, beta 2 (laminin S) 3 49121114-49133118 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000053, HPA001895, HPA050033, CAB078160 Supported Approved Vesicles
Cytosol Expressed in all parathyroid gland: 203.5 -USP19 KIAA0891, ZMYND9 ENSG00000172046 Ubiquitin specific peptidase 19 3 49108046-49120938 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 45.0 -QARS ENSG00000172053 Glutaminyl-tRNA synthetase 3 49095932-49105135 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036986, HPA036987 Supported Validated Cytosol Expressed in all rectum: 121.1 -ORMDL3 ENSG00000172057 ORMDL sphingolipid biosynthesis regulator 3 17 39921041-39927601 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065643 Supported Endoplasmic reticulum Expressed in all adipose tissue: 165.1 -SERF1A 4F5, FAM2A, H4F5, SERF1, SMAM1 ENSG00000172058 Small EDRK-rich factor 1A (telomeric) 5 70900665-70918530 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA075271 Approved Nuclear bodies Mixed cerebral cortex: 9.2 -KLF11 MODY7, TIEG2, Tieg3 ENSG00000172059 Kruppel-like factor 11 2 10042849-10054836 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA058276 Approved Nucleoplasm
Focal adhesion sites
Cytosol Expressed in all testis: 57.1 -LRRC15 LIB ENSG00000172061 Leucine rich repeat containing 15 3 194355247-194369743 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035503 Uncertain Approved Vesicles
Plasma membrane Mixed cervix: 4.7 -SMN1 BCD541, GEMIN1, SMA, SMA1, SMA2, SMA3, SMA@, SMNT, TDRD16A ENSG00000172062 Survival of motor neuron 1, telomeric 5 70925030-70953942 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB016324, HPA045271, CAB069888 Supported Supported Nuclear bodies
Cytosol Mixed lymph node: 17.9 -EIF2AK3 PEK, PERK ENSG00000172071 Eukaryotic translation initiation factor 2-alpha kinase 3 2 88556741-88627576 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009204, HPA015737 Approved Mixed parathyroid gland: 36.7 -TEX37 C2orf51, FLJ25369, TSC21 ENSG00000172073 Testis expressed 37 2 88524651-88529584 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043987 Supported Tissue enriched 515 testis: 82.0 placenta: 0.1 -MOB3A MOB-LAK, MOB1C, MOBKL2A, moblak ENSG00000172081 MOB kinase activator 3A 19 2071038-2096673 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057744 Uncertain Intermediate filaments
Cytosol Expressed in all lymph node: 86.5 -KRCC1 FLJ22333 ENSG00000172086 Lysine-rich coiled-coil 1 2 88027205-88055729 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA045618, HPA052666 Approved Approved Nucleoli
Cytosol Expressed in all parathyroid gland: 58.6 -NME6 IPIA-ALPHA, NM23-H6 ENSG00000172113 NME/NM23 nucleoside diphosphate kinase 6 3 48293264-48301685 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017909 Approved Approved Vesicles Expressed in all fallopian tube: 27.5 -CYCS CYC, HCS ENSG00000172115 Cytochrome c, somatic 7 25120091-25125361 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004222, CAB005126, CAB018597 Supported Validated Mitochondria Expressed in all heart muscle: 329.8 -CD8B CD8B1 ENSG00000172116 CD8b molecule 2 86815339-86861924 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB004353, HPA029164 Approved Supported Plasma membrane Tissue enhanced 0 cervix, uterine: 60.5;lymph node: 40.2 parathyroid gland: 22.4 -SLFN12 FLJ10260 ENSG00000172123 Schlafen family member 12 17 35411060-35433283 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA022523 Uncertain Mixed spleen: 13.4 -CALB2 CAL2 ENSG00000172137 Calbindin 2 16 71358713-71390438 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB000106, HPA007305, HPA007306 Supported Supported Validated Cytosol Tissue enhanced 0 adipose tissue: 54.5;testis: 24.9 adrenal gland: 12.7 -SLC9C1 NHE, SLC9A10 ENSG00000172139 Solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 3 112140887-112294258 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 9 skin: 2.9;testis: 14.1 thyroid gland: 0.9 -OR1A1 OR17-7 ENSG00000172146 Olfactory receptor, family 1, subfamily A, member 1 17 3215621-3216550 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -OR1A2 OR17-6 ENSG00000172150 Olfactory receptor, family 1, subfamily A, member 2 17 3197519-3198448 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -OR8I2 ENSG00000172154 Olfactory receptor, family 8, subfamily I, member 2 11 56093308-56094240 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -LCE1D LEP4 ENSG00000172155 Late cornified envelope 1D 1 152796751-152798181 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 305 skin: 101.4 skeletal muscle: 0.3 -CCL11 eotaxin, MGC22554, SCYA11 ENSG00000172156 Chemokine (C-C motif) ligand 11 17 34285668-34288334 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 appendix: 40.5;small intestine: 38.0 duodenum: 31.7 -FRMD3 EPB41L4O, MGC20553 ENSG00000172159 FERM domain containing 3 9 83242990-83538546 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA017285 Approved Approved Nucleoplasm
Golgi apparatus
Plasma membrane Tissue enhanced 0 heart muscle: 51.7 skeletal muscle: 28.6 -SNTB1 59-DAP, A1B, BSYN2, SNT2, SNT2B1, TIP-43 ENSG00000172164 Syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 8 120535745-120813273 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024659 Uncertain Tissue enhanced 0 thyroid gland: 102.1 adrenal gland: 74.0 -MTBP ENSG00000172167 MDM2 binding protein 8 120445400-120542133 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025694, HPA050594 Uncertain Approved Nucleus Mixed testis: 9.1 -TEFM C17orf42, FLJ22729 ENSG00000172171 Transcription elongation factor, mitochondrial 17 30897336-30906820 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023788, HPA053044 Approved Validated Mitochondria Mixed parathyroid gland: 6.3 -MRPL13 L13, L13A, L13mt, RPL13, RPML13 ENSG00000172172 Mitochondrial ribosomal protein L13 8 120380761-120445402 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060899 Approved Expressed in all kidney: 48.9 -MALT1 MLT, PCASP1 ENSG00000172175 MALT1 paracaspase 18 58671386-58754477 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004494, HPA048432 Supported Supported Nucleoli
Cytosol Expressed in all lymph node: 34.4 -PRL ENSG00000172179 Prolactin 6 22287244-22297501 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB023353, HPA042416, HPA062017 Supported Uncertain Cytosol Group enriched 8 endometrium: 10.7;placenta: 27.1 testis: 2.2 -ISG20 CD25, HEM45 ENSG00000172183 Interferon stimulated exonuclease gene 20kDa 15 88636153-88656483 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058356 Supported Nucleus Tissue enhanced 0 lymph node: 224.9 spleen: 138.9 -OR4C11 OR4C11P ENSG00000172188 Olfactory receptor, family 4, subfamily C, member 11 11 55603354-55604398 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -MBOAT1 dJ434O11.1, LPEAT1, MGC44669, OACT1 ENSG00000172197 Membrane bound O-acyltransferase domain containing 1 6 20102145-20212399 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052996 Approved Mitochondria Mixed fallopian tube: 55.1 -OR8U1 ENSG00000172199 Olfactory receptor, family 8, subfamily U, member 1 11 56375624-56376553 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -ID4 bHLHb27 ENSG00000172201 Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 6 19837386-19840684 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060800 Supported Nucleus Tissue enhanced 0 thyroid gland: 623.1 fallopian tube: 127.6 -GPR22 ENSG00000172209 G protein-coupled receptor 22 7 107470018-107475659 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 13 adrenal gland: 2.4;cerebral cortex: 9.5;cervix, uterine: 6.3;endometrium: 5.0;heart muscle: 11.9 smooth muscle: 0.5 -CXCR6 BONZO, CD186, STRL33, TYMSTR ENSG00000172215 Chemokine (C-X-C motif) receptor 6 3 45940933-45948353 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA047591 Uncertain Mixed lymph node: 17.6 -CEBPB C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5 ENSG00000172216 CCAAT/enhancer binding protein (C/EBP), beta 20 50190734-50192689 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004213, HPA061355, HPA062267 Supported Validated Nucleoplasm Expressed in all adrenal gland: 112.9 -AZU1 AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC ENSG00000172232 Azurocidin 1 19 825097-832018 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055851 Supported Tissue enriched 528 bone marrow: 1314.1 skin: 2.4 -TPSAB1 TPS1, TPS2, TPSB1 ENSG00000172236 Tryptase alpha/beta 1 16 1240696-1242554 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB016369, CAB022175, HPA049153, HPA049554 Supported Tissue enhanced 0 gallbladder: 212.7 lung: 158.8 -ATOH1 bHLHa14, HATH1, MATH-1, Math1 ENSG00000172238 Atonal bHLH transcription factor 1 4 93828753-93830964 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 9 colon: 18.0;duodenum: 11.4;rectum: 20.1;small intestine: 22.8 appendix: 2.0 -PAIP1 ENSG00000172239 Poly(A) binding protein interacting protein 1 5 43526267-43557758 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA076187 Approved Plasma membrane
Cytosol Expressed in all testis: 152.3 -CLEC7A CD369, CLECSF12, dectin-1, hDectin-1 ENSG00000172243 C-type lectin domain family 7, member A 12 10116777-10130258 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043244, HPA050229 Uncertain Approved Nucleoplasm
Vesicles Tissue enhanced 0 appendix: 67.3 bone marrow: 53.5 -C5orf34 FLJ32363 ENSG00000172244 Chromosome 5 open reading frame 34 5 43486701-43515145 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045386 Approved Tissue enhanced 0 testis: 7.9 prostate: 3.8 -C1QTNF4 CTRP4, ZACRP4 ENSG00000172247 C1q and tumor necrosis factor related protein 4 11 47589664-47594659 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041032 Approved Tissue enriched 6 cerebral cortex: 28.3 parathyroid gland: 5.1 -NEGR1 IGLON4, KILON, MGC46680, Ntra ENSG00000172260 Neuronal growth regulator 1 1 71395940-72282734 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011894 Uncertain Approved Vesicles
Actin filaments
Cytosol Tissue enhanced 0 cerebral cortex: 56.3 gallbladder: 17.5 -ZNF131 pHZ-10, ZBTB35 ENSG00000172262 Zinc finger protein 131 5 43065176-43192021 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007023, HPA027748, HPA074630 Approved Validated Nucleoplasm
Intermediate filaments Expressed in all testis: 59.1 -MACROD2 C20orf133, dJ631M13.5 ENSG00000172264 MACRO domain containing 2 20 13995369-16053197 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049076 Approved Supported Nucleus
Nucleoli
Centrosome Mixed lung: 16.3 -DPAGT1 ALG7, CDG-Ij, D11S366, DGPT, DPAGT, DPAGT2, GPT ENSG00000172269 Dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 11 119096503-119108331 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053878 Approved Mixed parathyroid gland: 30.3 -BSG CD147, EMMPRIN, OK ENSG00000172270 Basigin (Ok blood group) 19 571277-583493 Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002427, HPA036048, HPA074870 Supported Approved Vesicles Expressed in all heart muscle: 585.9 -HINFP DKFZP434F162, HiNF-P, MIZF, ZNF743 ENSG00000172273 Histone H4 transcription factor 11 119121587-119136044 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059053, HPA061008 Uncertain Supported Nucleus
Cell Junctions
Cytosol Expressed in all testis: 12.0 -CDY1 CDY1A ENSG00000172288 Chromodomain protein, Y-linked, 1 Y 25622162-25624902 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 testis: 1.0 epididymis: 0.0 -OR10V1 ENSG00000172289 Olfactory receptor, family 10, subfamily V, member 1 11 59712823-59713864 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA060076 Uncertain Not detected cervix: 0.2 -CERS6 LASS6 ENSG00000172292 Ceramide synthase 6 2 168455862-168775137 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044683, HPA063527 Approved Supported Nucleus Expressed in all thyroid gland: 43.4 -SPTLC3 C20orf38, FLJ11112, hLCB2b, LCB2B, SPTLC2L ENSG00000172296 Serine palmitoyltransferase, long chain base subunit 3 20 13008979-13169103 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044247, HPA048079 Approved Supported Microtubules Mixed thyroid gland: 40.7 -COPRS C17orf79, COPR5, HSA272196, TTP1 ENSG00000172301 Coordinator of PRMT5, differentiation stimulator 17 31851864-31859337 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052552 Approved Supported Nucleus
Plasma membrane
Cytosol Expressed in all testis: 266.6 -TP53RK BUD32, C20orf64, dJ101A2.2, Nori-2p, prpk ENSG00000172315 TP53 regulating kinase 20 46684365-46689779 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004688, HPA015837 Approved Expressed in all testis: 16.5 -B3GALT1 beta3Gal-T1 ENSG00000172318 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 2 167868948-167874041 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 5.2;colon: 3.8;rectum: 4.1 skeletal muscle: 1.8 -OR5A1 OR5A1P, OST181 ENSG00000172320 Olfactory receptor, family 5, subfamily A, member 1 11 59443144-59444194 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.1 -CLEC12A CD371, CLL-1, DCAL-2, MICL ENSG00000172322 C-type lectin domain family 12, member A 12 9951316-9995694 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048515 Supported Tissue enhanced 0 bone marrow: 51.4 spleen: 27.1 -OR5A2 ENSG00000172324 Olfactory receptor, family 5, subfamily A, member 2 11 59421943-59422976 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA047135, HPA049575 Uncertain Not detected epididymis: 0.0 -BPGM ENSG00000172331 2,3-bisphosphoglycerate mutase 7 134646808-134679813 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016493, HPA028735 Supported Approved Nucleoli Expressed in all placenta: 64.7 -POP7 RPP2, RPP20 ENSG00000172336 POP7 homolog, ribonuclease P/MRP subunit 7 100706053-100707495 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021007 Uncertain Supported Nucleoli
Vesicles Expressed in all cerebral cortex: 41.2 -ALG14 MGC19780 ENSG00000172339 ALG14, UDP-N-acetylglucosaminyltransferase subunit 1 94974407-95072945 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031829 Approved Approved Nucleus
Nucleoli Mixed epididymis: 3.1 -SUCLG2 ENSG00000172340 Succinate-CoA ligase, GDP-forming, beta subunit 3 67360460-67654614 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046705, HPA051998 Supported Supported Plasma membrane
Mitochondria Expressed in all colon: 171.4 -STARD5 MGC10327 ENSG00000172345 StAR-related lipid transfer (START) domain containing 5 15 81309053-81324183 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040662 Approved Mixed spleen: 10.6 -CSDC2 PIPPin ENSG00000172346 Cold shock domain containing C2, RNA binding 22 41560763-41577741 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003073, HPA076549 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 adrenal gland: 62.8;ovary: 72.1 heart muscle: 45.8 -RCAN2 DSCR1L1, ZAKI-4 ENSG00000172348 Regulator of calcineurin 2 6 46220736-46491972 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA053880 Uncertain Approved Nucleoplasm
Mitochondria Mixed parathyroid gland: 142.7 -IL16 FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16 ENSG00000172349 Interleukin 16 15 81159575-81314058 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005247, HPA018467 Supported Approved Nuclear speckles
Plasma membrane
Cytosol Tissue enhanced 0 lymph node: 156.4;tonsil: 128.4 spleen: 120.1 -ABCG4 WHITE2 ENSG00000172350 ATP-binding cassette, sub-family G (WHITE), member 4 11 119149012-119162653 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040312 Uncertain Group enriched 6 cerebral cortex: 6.6;parathyroid gland: 4.0;testis: 5.1 seminal vesicle: 0.8 -CDY1B ENSG00000172352 Chromodomain protein, Y-linked, 1B Y 24045229-24048019 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 40 testis: 3.9 epididymis: 0.0 -GNB2 ENSG00000172354 Guanine nucleotide binding protein (G protein), beta polypeptide 2 7 100673531-100679174 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010032, HPA040736 Approved Approved Plasma membrane Expressed in all esophagus: 236.4 -CFAP53 CCDC11, FLJ32743 ENSG00000172361 Cilia and flagella associated protein 53 18 50227193-50266522 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040595, HPA041069 Supported Approved Midbody Group enriched 12 fallopian tube: 44.1;testis: 126.4 epididymis: 6.8 -OR5B12 OR5B12P, OR5B16, OST743 ENSG00000172362 Olfactory receptor, family 5, subfamily B, member 12 11 58439120-58440173 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -OR5B2 OST073 ENSG00000172365 Olfactory receptor, family 5, subfamily B, member 2 11 58422265-58423313 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.2 -FAM195A C16orf14, MGC15416 ENSG00000172366 Family with sequence similarity 195, member A 16 636817-648474 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060363 Uncertain Mixed colon: 11.0 -PDZD3 FLJ22756, IKEPP, PDZK2 ENSG00000172367 PDZ domain containing 3 11 119185457-119190223 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 duodenum: 17.8;kidney: 10.8;small intestine: 21.6 rectum: 6.8 -C2CD2L KIAA0285, TMEM24 ENSG00000172375 C2CD2-like 11 119102198-119118544 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011044 Approved Approved Nucleus
Nuclear membrane
Nucleoli
Cytosol Expressed in all cerebral cortex: 29.7 -OR9I1 ENSG00000172377 Olfactory receptor, family 9, subfamily I, member 1 11 58118500-58119444 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -ARNT2 bHLHe1, KIAA0307 ENSG00000172379 Aryl-hydrocarbon receptor nuclear translocator 2 15 80404350-80597937 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001056, CAB005081 Approved Approved Nucleus
Mitochondria Tissue enriched 8 cerebral cortex: 154.5 testis: 19.3 -GNG12 ENSG00000172380 Guanine nucleotide binding protein (G protein), gamma 12 1 67701466-67833467 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057790, HPA062208 Supported Approved Mitochondria Mixed duodenum: 125.7 -OR6Q1 ENSG00000172381 Olfactory receptor, family 6, subfamily Q, member 1 (gene/pseudogene) 11 58030953-58031906 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -PRSS27 CAPH2, marapsin, MPN, pancreasin ENSG00000172382 Protease, serine 27 16 2712418-2720551 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB024920 Approved Tissue enriched 7 esophagus: 211.6 tonsil: 29.0 -MYOZ2 C4orf5, CS-1 ENSG00000172399 Myozenin 2 4 119135784-119187789 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035763, HPA035764 Supported Approved Nucleus
Cytosol Tissue enriched 8 heart muscle: 476.7 skeletal muscle: 63.4 -SYNPO2 MYOPODIN ENSG00000172403 Synaptopodin 2 4 118850688-119061247 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030665, CAB037231, HPA049707, HPA068563 Supported Supported Vesicles
Actin filaments
Cytosol Tissue enhanced 0 seminal vesicle: 417.5 smooth muscle: 339.8 -DNAJB7 HSC3 ENSG00000172404 DnaJ (Hsp40) homolog, subfamily B, member 7 22 40859549-40862126 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000534 Approved Tissue enriched 17 testis: 10.2 small intestine: 0.5 -CLP1 hClp1, HEAB ENSG00000172409 Cleavage and polyadenylation factor I subunit 1 11 57648992-57661868 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057770 Supported Supported Nucleoplasm Expressed in all bone marrow: 17.1 -INSL5 ENSG00000172410 Insulin-like 5 1 66797741-66801256 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA030100, CAB033849 Supported Group enriched 231 colon: 79.8;rectum: 143.8 testis: 0.4 -EFCAB3 FLJ25818 ENSG00000172421 EF-hand calcium binding domain 3 17 62370218-62416476 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046862 Uncertain Tissue enriched 24 testis: 10.5 adipose tissue: 0.4 -TTC36 HBP21 ENSG00000172425 Tetratricopeptide repeat domain 36 11 118527472-118531197 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038731 Supported Uncertain Nucleoplasm Tissue enhanced 0 liver: 64.3 epididymis: 15.0 -RSPH9 C6orf206, CILD12, FLJ30845, MRPS18AL1 ENSG00000172426 Radial spoke head 9 homolog (Chlamydomonas) 6 43645046-43672599 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031703 Supported Group enriched 6 fallopian tube: 14.5;testis: 12.6 lung: 2.2 -MYEOV2 ENSG00000172428 Myeloma overexpressed 2 2 240126563-240136807 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044845 Uncertain Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 192.6 -GTPBP2 ENSG00000172432 GTP binding protein 2 6 43605316-43629162 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031418, HPA031419 Approved Validated Vesicles Expressed in all parathyroid gland: 46.5 -FGGY FLJ10986 ENSG00000172456 FGGY carbohydrate kinase domain containing 1 59296638-59810647 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054971 Approved Nucleoplasm
Nuclear bodies Expressed in all epididymis: 43.6 -OR9G4 ENSG00000172457 Olfactory receptor, family 9, subfamily G, member 4 11 56742827-56743811 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -IL17D FLJ30846, IL-17D, IL-22, IL-27, IL27 ENSG00000172458 Interleukin 17D 13 20702127-20723098 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 100.5 skeletal muscle: 45.9 -FUT9 Fuc-TIX ENSG00000172461 Fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 6 96015984-96215612 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA070923 Approved Nucleoplasm
Microtubules
Cytokinetic bridge
Cytosol Group enriched 12 cerebral cortex: 28.2;stomach: 22.2 duodenum: 2.1 -OR5AP2 ENSG00000172464 Olfactory receptor, family 5, subfamily AP, member 2 11 56641466-56642471 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -TCEAL1 p21, pp21, SIIR, WEX9 ENSG00000172465 Transcription elongation factor A (SII)-like 1 X 103628704-103630953 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057345 Supported Nucleoplasm Expressed in all ovary: 146.1 -ZNF24 KOX17, Zfp191, ZNF191, ZSCAN3 ENSG00000172466 Zinc finger protein 24 18 35332212-35345482 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024062, CAB025642 Supported Supported Nucleus Expressed in all parathyroid gland: 56.2 -HSFY1 HSF2L, HSFY ENSG00000172468 Heat shock transcription factor, Y-linked 1 Y 18546671-18588963 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 106 testis: 24.7 epididymis: 0.2 -MANEA FLJ12838, mandaselin ENSG00000172469 Mannosidase, endo-alpha 6 95577543-95609457 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011046, HPA011069 Supported Supported Golgi apparatus Mixed thyroid gland: 19.4 -RAB40A Rar-2, RAR2A ENSG00000172476 RAB40A, member RAS oncogene family X 103499750-103519489 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 9.2 esophagus: 7.6 -C2orf54 FLJ22671 ENSG00000172478 Chromosome 2 open reading frame 54 2 240886048-240896889 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052722 Approved Nucleoplasm
Golgi apparatus Tissue enhanced 0 esophagus: 112.6;skin: 51.5 tonsil: 26.7 -AGXT AGT, AGT1, AGXT1, PH1, SPAT, SPT ENSG00000172482 Alanine-glyoxylate aminotransferase 2 240868479-240880502 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035370, HPA035371 Supported Supported Vesicles Tissue enriched 59 liver: 611.6 kidney: 10.3 -OR8J1 ENSG00000172487 Olfactory receptor, family 8, subfamily J, member 1 11 56360215-56361288 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -OR5T3 OR5T3Q ENSG00000172489 Olfactory receptor, family 5, subfamily T, member 3 11 56252200-56253222 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA044986 Uncertain Not detected epididymis: 0.0 -AFF1 AF-4, AF4, MLLT2, PBM1 ENSG00000172493 AF4/FMR2 family, member 1 4 86935002-87141054 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069947 Approved Nucleoplasm
Mitochondria Expressed in all thyroid gland: 91.1 -ACOT12 Cach, STARD15, THEAL ENSG00000172497 Acyl-CoA thioesterase 12 5 81330005-81394179 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037723, HPA037724 Uncertain Approved Nucleoplasm
Cytosol Tissue enriched 19 liver: 51.3 kidney: 2.7 -FIBP FGFIBP ENSG00000172500 Fibroblast growth factor (acidic) intracellular binding protein 11 65883741-65888539 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011729 Approved Supported Nuclear speckles Expressed in all testis: 78.6 -CARNS1 ATPGD1, KIAA1394 ENSG00000172508 Carnosine synthase 1 11 67414968-67425607 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038569 Approved Group enriched 9 cerebral cortex: 37.2;skeletal muscle: 25.9 heart muscle: 3.4 -OR10H5 ENSG00000172519 Olfactory receptor, family 10, subfamily H, member 5 19 15793951-15795082 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -BANP BEND1, DKFZp761H172, FLJ10177, FLJ20538, SMAR1, SMARBP1 ENSG00000172530 BTG3 associated nuclear protein 16 87949244-88118422 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047164 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 14.1 -PPP1CA PP-1A, PP1A, PP1alpha, PPP1A ENSG00000172531 Protein phosphatase 1, catalytic subunit, alpha isozyme 11 67398183-67421183 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004545, HPA046833 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all lymph node: 168.7 -HCFC1 CFF, HCF-1, HCF1, HFC1, MGC70925, MRX3, PPP1R89, VCAF ENSG00000172534 Host cell factor C1 X 153947553-153971807 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018312 Supported Nucleoplasm
Mitochondria Expressed in all bone marrow: 24.7 -FAM170B C10orf73, Em:AC084727.4 ENSG00000172538 Family with sequence similarity 170, member B 10 49131154-49134008 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043899, HPA050610 Uncertain Tissue enriched 75 testis: 7.4 epididymis: 0.0 -CTSW ENSG00000172543 Cathepsin W 11 65879809-65883741 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016345 Supported Tissue enhanced 0 bone marrow: 70.8;spleen: 61.4 lung: 36.5 -NIPAL4 ICHYN ENSG00000172548 NIPA-like domain containing 4 5 157460019-157474717 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA038259 Approved Tissue enhanced 0 skin: 42.0 esophagus: 10.2 -MUCL1 SBEM ENSG00000172551 Mucin-like 1 12 54830519-54858393 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039093 Supported Tissue enriched 42 breast: 3725.6 salivary gland: 89.6 -SNTG2 G2SYN, SYN5 ENSG00000172554 Syntrophin, gamma 2 2 950868-1367613 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 spleen: 2.5;testis: 2.3 endometrium: 2.0 -FNDC9 C5orf40, MGC27121 ENSG00000172568 Fibronectin type III domain containing 9 5 157341600-157345721 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA011115, HPA017291 Approved Group enriched 17 adrenal gland: 6.3;cerebral cortex: 20.7 appendix: 0.7 -PDE3A CGI-PDE ENSG00000172572 Phosphodiesterase 3A, cGMP-inhibited 12 20369245-20684381 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014492 Uncertain Supported Cytosol Tissue enhanced 0 heart muscle: 38.3 placenta: 31.1 -RASGRP1 CalDAG-GEFII, RASGRP ENSG00000172575 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 15 38488103-38565575 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046216 Supported Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 28.5;lymph node: 25.3 tonsil: 15.8 -KLHL6 FLJ00029 ENSG00000172578 Kelch-like family member 6 3 183487531-183555689 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA024512 Uncertain Tissue enhanced 0 lymph node: 35.7;tonsil: 29.9 appendix: 16.6 -CHCHD1 C10orf34, FLJ25854 ENSG00000172586 Coiled-coil-helix-coiled-coil-helix domain containing 1 10 73782047-73783652 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039046 Approved Supported Nucleoplasm
Nucleoli fibrillar center
Mitochondria Expressed in all epididymis: 61.6 -MRPL52 ENSG00000172590 Mitochondrial ribosomal protein L52 14 22829879-22835037 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012319 Approved Approved Mitochondria Expressed in all appendix: 74.7 -SMPDL3A ASM3A, ASML3a, FLJ20177, yR36GH4.1 ENSG00000172594 Sphingomyelin phosphodiesterase, acid-like 3A 6 122789049-122809720 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030148 Uncertain Approved Nucleus
Nucleoli
Mitochondria Expressed in all small intestine: 83.5 -RND1 ARHS, Rho6, RHOS ENSG00000172602 Rho family GTPase 1 12 48857145-48865898 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA077800 Supported Vesicles
Plasma membrane
Actin filaments Tissue enhanced 0 cerebral cortex: 39.9;liver: 31.0 gallbladder: 23.7 -RAD9A RAD9 ENSG00000172613 RAD9 checkpoint clamp component A 11 67317871-67398410 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006725, HPA048155 Supported Validated Nucleoplasm Expressed in all fallopian tube: 14.9 -EFEMP2 FBLN4, UPH1 ENSG00000172638 EGF containing fibulin-like extracellular matrix protein 2 11 65866441-65873592 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023270 Approved Expressed in all cervix: 49.9 -OR10AD1 OR10AD1P ENSG00000172640 Olfactory receptor, family 10, subfamily AD, member 1 12 48202083-48203387 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049913 Uncertain Mixed testis: 1.2 -AGAP5 CTGLF2, Em:AC073389.1 ENSG00000172650 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 10 73674285-73698159 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042490 Uncertain Mixed testis: 11.8 -FAM21C Em:AC012044.3, KIAA0592 ENSG00000172661 Family with sequence similarity 21, member C 10 45727200-45792961 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047844, HPA060975 Approved Supported Nucleoli
Vesicles
Cytosol Expressed in all parathyroid gland: 41.2 -TMEM134 FLJ21749 ENSG00000172663 Transmembrane protein 134 11 67461710-67469272 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043744 Approved Supported Cytosol Expressed in all skin: 38.4 -ZMAT3 FLJ12296, MGC10613, PAG608, WIG-1, WIG1 ENSG00000172667 Zinc finger, matrin-type 3 3 179017223-179072279 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028671, HPA054356 Supported Nucleoplasm Mixed cerebral cortex: 29.1 -ZFAND4 ANUBL1, FLJ40185 ENSG00000172671 Zinc finger, AN1-type domain 4 10 45615501-45672780 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037839, HPA057543 Uncertain Approved Golgi apparatus Tissue enriched 12 testis: 94.8 lymph node: 7.6 -THEMIS bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA ENSG00000172673 Thymocyte selection associated 6 127708072-127918631 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031422, HPA031425 Supported Tissue enhanced 0 lymph node: 8.6 spleen: 4.6 -MOS ENSG00000172680 V-mos Moloney murine sarcoma viral oncogene homolog 8 56112942-56113982 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA040424 Uncertain Not detected testis: 0.9 -ZNF738 ENSG00000172687 Zinc finger protein 738 19 21358930-21379302 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA059135 Uncertain Mixed ovary: 11.8 -MS4A10 CD20L7, MS4A9 ENSG00000172689 Membrane-spanning 4-domains, subfamily A, member 10 11 60785348-60801305 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014778 Uncertain Group enriched 93 duodenum: 76.3;small intestine: 97.7 parathyroid gland: 0.9 -SLFN11 FLJ34922 ENSG00000172716 Schlafen family member 11 17 35350305-35373701 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023030, HPA062062 Uncertain Validated Nucleoplasm Expressed in all lung: 56.1 -FAM71D C14orf54 ENSG00000172717 Family with sequence similarity 71, member D 14 67189393-67228550 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 16 testis: 24.0 epididymis: 1.4 -CCL19 CKb11, ELC, exodus-3, MIP-3b, SCYA19 ENSG00000172724 Chemokine (C-C motif) ligand 19 9 34689567-34691277 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067758 Supported Group enriched 5 adipose tissue: 171.7;appendix: 807.5;lymph node: 715.5;tonsil: 578.1 urinary bladder: 110.3 -CORO1B coronin-2 ENSG00000172725 Coronin, actin binding protein, 1B 11 67435510-67443821 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017616, HPA040113, HPA070456 Supported Validated Plasma membrane
Cytosol Expressed in all prostate: 77.2 -FUT10 ENSG00000172728 Fucosyltransferase 10 (alpha (1,3) fucosyltransferase) 8 33370824-33473422 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA053970, HPA058655 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Golgi apparatus Mixed parathyroid gland: 8.6 -LRRC20 FLJ10751, FLJ10844 ENSG00000172731 Leucine rich repeat containing 20 10 70298970-70382650 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039630 Approved Nucleoplasm
Cytosol Tissue enhanced 0 skeletal muscle: 120.6 heart muscle: 27.1 -MUS81 FLJ44872, SLX3 ENSG00000172732 MUS81 structure-specific endonuclease subunit 11 65857126-65867653 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059530 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all endometrium: 25.2 -PURG PURG-A, PURG-B ENSG00000172733 Purine-rich element binding protein G 8 30995802-31033715 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047746 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Tissue enhanced 0 cerebral cortex: 6.6;testis: 4.8 endometrium: 2.6 -TMEM217 C6orf128, dJ355M6.2 ENSG00000172738 Transmembrane protein 217 6 37212180-37258155 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 14 testis: 14.1 adrenal gland: 1.0 -OR4D9 ENSG00000172742 Olfactory receptor, family 4, subfamily D, member 9 11 59514913-59515857 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -ZNF596 ENSG00000172748 Zinc finger protein 596 8 232137-247342 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055463 Uncertain Approved Nucleoli
Mitochondria Tissue enhanced 0 testis: 27.3 parathyroid gland: 12.9 -COL6A5 COL29A1, FLJ35880, VWA4 ENSG00000172752 Collagen, type VI, alpha 5 3 130345516-130484844 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA043138 Uncertain Group enriched 6 lung: 3.8;skin: 7.4 duodenum: 0.9 -CFL1 CFL ENSG00000172757 Cofilin 1 (non-muscle) 11 65823022-65862026 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033687, CAB037077, HPA053761 Approved Expressed in all appendix: 1266.2 -TMCC1 KIAA0779 ENSG00000172765 Transmembrane and coiled-coil domain family 1 3 129647792-129893576 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053894 Uncertain Expressed in all testis: 25.1 -NAA16 FLJ22054, MGC40612, NARG1L, PRO2435 ENSG00000172766 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 13 41311205-41377030 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039761, HPA040157 Approved Validated Cytosol Expressed in all bone marrow: 14.5 -OR5B3 OR5B13, OST129 ENSG00000172769 Olfactory receptor, family 5, subfamily B, member 3 11 58402464-58403409 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -EFCAB12 C3orf25 ENSG00000172771 EF-hand calcium binding domain 12 3 129401321-129428651 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA037694 Uncertain Group enriched 5 fallopian tube: 30.8;testis: 6.7 prostate: 3.5 -OR10W1 OR10W1P ENSG00000172772 Olfactory receptor, family 10, subfamily W, member 1 11 58266792-58268260 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -OR1S1 OST034 ENSG00000172774 Olfactory receptor, family 1, subfamily S, member 1 (gene/pseudogene) 11 58214745-58215722 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA049304 Uncertain Not detected epididymis: 0.0 -FAM192A C16orf94, NIP30 ENSG00000172775 Family with sequence similarity 192, member A 16 57152466-57186116 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054382, HPA059652 Uncertain Supported Nucleoplasm
Vesicles Expressed in all testis: 175.6 -RAB43 ISY1, RAB11B, RAB41 ENSG00000172780 RAB43, member RAS oncogene family 3 129087569-129122801 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046840, HPA060085 Approved Supported Plasma membrane Mixed thyroid gland: 37.4 -FADS6 ENSG00000172782 Fatty acid desaturase 6 17 74877299-74893781 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA016802 Uncertain Tissue enhanced 0 epididymis: 22.6 small intestine: 10.3 -CBWD1 ENSG00000172785 COBW domain containing 1 9 121038-179147 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042759, HPA042813 Approved Approved Plasma membrane Expressed in all adrenal gland: 45.0 -HOXC5 HOX3, HOX3D ENSG00000172789 Homeobox C5 12 54032853-54035358 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level No evidence HPA026794 Uncertain Supported Nucleoplasm Tissue enhanced 0 fallopian tube: 6.0 ovary: 3.1 -RAB37 ENSG00000172794 RAB37, member RAS oncogene family 17 74670578-74747335 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed spleen: 21.2 -DCP2 NUDT20 ENSG00000172795 Decapping mRNA 2 5 112976702-113020970 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB011677, HPA057676 Approved Approved Nucleoplasm
Cell Junctions
Cytoplasmic bodies Mixed placenta: 18.8 -SNX32 FLJ30934, SNX6B ENSG00000172803 Sorting nexin 32 11 65833641-65856896 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041775 Uncertain Uncertain Cell Junctions
Focal adhesion sites Tissue enhanced 0 cerebral cortex: 7.8 testis: 1.7 -RPL38 L38 ENSG00000172809 Ribosomal protein L38 17 74203582-74210655 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052543 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all ovary: 2575.5 -CYP7B1 SPG5A ENSG00000172817 Cytochrome P450, family 7, subfamily B, polypeptide 1 8 64587763-64798761 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017761 Uncertain Tissue enhanced 0 parathyroid gland: 39.6 thyroid gland: 22.3 -OVOL1 HOVO1 ENSG00000172818 Ovo-like zinc finger 1 11 65787022-65797219 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA003984 Uncertain Approved Nucleus Tissue enhanced 0 esophagus: 37.4;skin: 33.5;testis: 35.3 urinary bladder: 16.0 -RARG NR1B3, RARC ENSG00000172819 Retinoic acid receptor, gamma 12 53210567-53232980 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA053883 Supported Supported Nucleoplasm Tissue enhanced 0 skin: 143.7 esophagus: 77.6 -CES4A CES8, FLJ37464 ENSG00000172824 Carboxylesterase 4A 16 66988589-67009758 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA035701 Approved Approved Cytosol Group enriched 7 fallopian tube: 28.2;skin: 9.2 epididymis: 2.7 -CES3 ES31, FLJ21736 ENSG00000172828 Carboxylesterase 3 16 66961237-66975148 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041008, HPA041307 Approved Approved Nuclear membrane
Endoplasmic reticulum Tissue enhanced 0 colon: 37.9;duodenum: 31.3;rectum: 34.8 small intestine: 27.1 -SSH3 FLJ10928, FLJ20515 ENSG00000172830 Slingshot protein phosphatase 3 11 67303448-67312607 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019949, HPA019957 Approved Approved Nuclear speckles
Plasma membrane
Actin filaments
Cytosol Expressed in all seminal vesicle: 37.1 -CES2 CE-2, CES2A1, iCE ENSG00000172831 Carboxylesterase 2 16 66934444-66945096 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018897 Supported Approved Golgi apparatus
Cytosol Expressed in all duodenum: 541.7 -PDP2 KIAA1348, PPM2C2 ENSG00000172840 Pyruvate dehyrogenase phosphatase catalytic subunit 2 16 66878589-66895754 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019950, HPA062059 Approved Supported Mitochondria Mixed thyroid gland: 15.5 -SP3 SPR-2 ENSG00000172845 Sp3 transcription factor 2 173906459-173965702 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004580, HPA032145 Approved Supported Expressed in all thyroid gland: 79.3 -KRT2 KRT2A, KRTE ENSG00000172867 Keratin 2, type II 12 52644558-52652164 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006299, CAB037321 Supported Approved Golgi apparatus
Intermediate filaments
Cytosol Tissue enriched 24 skin: 2606.5 breast: 110.8 -DMXL1 ENSG00000172869 Dmx-like 1 5 119037772-119249138 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036431, HPA036432 Approved Supported Nucleoli
Cytosol Mixed prostate: 42.1 -METAP1D MAP1D, Metap1l ENSG00000172878 Methionyl aminopeptidase type 1D (mitochondrial) 2 171999583-172082430 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030298, HPA030299 Uncertain Supported Vesicles Mixed ovary: 9.2 -ZNF621 FLJ45246 ENSG00000172888 Zinc finger protein 621 3 40524878-40574685 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA065518, HPA071440 Supported Nuclear speckles Expressed in all parathyroid gland: 22.9 -EGFL7 ZNEU1 ENSG00000172889 EGF-like-domain, multiple 7 9 136658856-136672678 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB020815 Approved Expressed in all placenta: 262.5 -NADSYN1 FLJ10631 ENSG00000172890 NAD synthetase 1 11 71453109-71524107 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017798, HPA038523, HPA038524 Approved Validated Cytosol Expressed in all spleen: 42.1 -DHCR7 SLOS ENSG00000172893 7-dehydrocholesterol reductase 11 71428193-71452868 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044280 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all adrenal gland: 116.0 -LVRN APQ, AQPEP, FLJ90650, TAQPEP ENSG00000172901 Laeverin 5 115962454-116027619 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053254 Approved Group enriched 22 adipose tissue: 11.8;placenta: 31.2 breast: 0.9 -NBEA BCL8B, FLJ10197, KIAA1544 ENSG00000172915 Neurobeachin 13 34942287-35673022 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039730, HPA040385 Approved Approved Nucleus
Nucleoli
Golgi apparatus Tissue enhanced 0 cerebral cortex: 30.4 prostate: 12.3 -RNASEH2C AGS3, AYP1 ENSG00000172922 Ribonuclease H2, subunit C 11 65714896-65720947 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065375 Approved Nucleus Expressed in all cerebral cortex: 25.1 -MYEOV OCIM ENSG00000172927 Myeloma overexpressed 11 69294138-69367726 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA012949 Uncertain Approved Nucleus
Vesicles Group enriched 5 adipose tissue: 4.0;breast: 5.8;esophagus: 9.2;skin: 1.8;stomach: 7.0 appendix: 1.0 -ANKRD13D ENSG00000172932 Ankyrin repeat domain 13 family, member D 11 67288547-67302485 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039950 Approved Approved Nucleus
Mitochondria Expressed in all bone marrow: 69.5 -MRGPRF GPR140, GPR168, MGC21621, mrgF ENSG00000172935 MAS-related GPR, member F 11 69004395-69013409 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028811 Approved Supported Nuclear membrane
Plasma membrane Mixed smooth muscle: 77.8 -MYD88 ENSG00000172936 Myeloid differentiation primary response 88 3 38138478-38143022 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009104 Approved Supported Vesicles
Mitochondria
Cytosol Mixed appendix: 57.6 -MRGPRD mrgD ENSG00000172938 MAS-related GPR, member D 11 68980021-68980986 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA031346 Uncertain Not detected seminal vesicle: 0.4 -OXSR1 KIAA1101, OSR1 ENSG00000172939 Oxidative stress responsive 1 3 38165089-38255488 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008237, CAB017181 Supported Validated Cytosol Expressed in all parathyroid gland: 42.3 -SLC22A13 OAT10, OCTL1, OCTL3, ORCTL3 ENSG00000172940 Solute carrier family 22 (organic anion/urate transporter), member 13 3 38265812-38278315 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA035603, HPA035962 Supported Tissue enriched 39 kidney: 10.6 testis: 0.2 -PHF8 JHDM1F, KIAA1111, ZNF422 ENSG00000172943 PHD finger protein 8 X 53936676-54048958 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038779, HPA062015 Approved Supported Nucleus Expressed in all epididymis: 84.6 -LCLAT1 AGPAT8, ALCAT1, FLJ37965, LYCAT ENSG00000172954 Lysocardiolipin acyltransferase 1 2 30447226-30644225 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031880, HPA049217 Uncertain Supported Endoplasmic reticulum
Cytosol Expressed in all thyroid gland: 19.2 -ADH6 ADH-5 ENSG00000172955 Alcohol dehydrogenase 6 (class V) 4 99202638-99219537 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 liver: 359.2 kidney: 53.1 -XKR3 MGC57211, XTES ENSG00000172967 XK, Kell blood group complex subunit-related family, member 3 22 16783412-16821699 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003379, HPA035081 Uncertain Tissue enriched 80 testis: 14.3 cerebral cortex: 0.1 -FRG2C ENSG00000172969 FSHD region gene 2 family, member C 3 75664330-75667220 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA039264, HPA047769 Uncertain Tissue enhanced 0 testis: 1.0 kidney: 0.7 -KAT5 cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5 ENSG00000172977 K(lysine) acetyltransferase 5 11 65711996-65719604 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016953 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 81.9 -SH3RF3 FLJ00204, POSH2, SH3MD4 ENSG00000172985 SH3 domain containing ring finger 3 2 109129348-109504632 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044822, HPA048444 Approved Validated Nucleoplasm
Centrosome
Cytosol Mixed placenta: 7.6 -GXYLT2 GLT8D4 ENSG00000172986 Glucoside xylosyltransferase 2 3 72888073-72998138 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA068429 Uncertain Approved Nucleoplasm
Cytokinetic bridge
Midbody ring Mixed ovary: 20.5 -HPSE2 HPA2, HPR2, UFS ENSG00000172987 Heparanase 2 (inactive) 10 98457077-99235862 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044603 Uncertain Tissue enhanced 0 cervix, uterine: 53.9 esophagus: 22.8 -DCAKD FLJ22955 ENSG00000172992 Dephospho-CoA kinase domain containing 17 45023340-45061109 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060997 Approved Nucleus Expressed in all cerebral cortex: 47.2 -ARPP21 ARPP-21, R3HDM3, TARPP ENSG00000172995 CAMP-regulated phosphoprotein, 21kDa 3 35638945-35794496 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017303 Supported Approved Nucleoli
Cytosol Tissue enriched 6 cerebral cortex: 127.5 skeletal muscle: 20.2 -TADA2B MGC21874 ENSG00000173011 Transcriptional adaptor 2B 4 7041899-7057952 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035770 Approved Approved Nuclear speckles Expressed in all thyroid gland: 27.4 -CCDC96 FLJ90575 ENSG00000173013 Coiled-coil domain containing 96 4 7040849-7042939 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047546 Approved Group enriched 14 fallopian tube: 17.6;testis: 61.6 lung: 2.7 -ADRBK1 BARK1, GRK2 ENSG00000173020 Adrenergic, beta, receptor kinase 1 11 67266410-67286556 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005021, CAB037248, HPA048330 Approved Approved Vesicles Expressed in all spleen: 129.5 -RELA NFKB3, p65 ENSG00000173039 V-rel avian reticuloendotheliosis viral oncogene homolog A 11 65653596-65663094 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004264, CAB005030, HPA063461 Supported Validated Cytosol Expressed in all endometrium: 62.1 -EVC2 LBN ENSG00000173040 Ellis van Creveld syndrome 2 4 5542772-5709548 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040910, HPA048122 Uncertain Approved Mitochondria Mixed ovary: 8.8 -ZNF680 FLJ90430 ENSG00000173041 Zinc finger protein 680 7 64519884-64563106 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003173 Approved Nucleus Expressed in all thyroid gland: 42.3 -HECTD4 C12orf51, FLJ34154, KIAA0614 ENSG00000173064 HECT domain containing E3 ubiquitin protein ligase 4 12 112160188-112382439 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041062, HPA045473 Uncertain Approved Nucleoplasm
Vesicles Expressed in all cerebral cortex: 19.4 -FAM222B C17orf63, FLJ10700 ENSG00000173065 Family with sequence similarity 222, member B 17 28755978-28855232 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051840, HPA062239 Approved Validated Nucleoplasm Expressed in all testis: 50.8 -BNC2 BSN2, FLJ20043 ENSG00000173068 Basonuclin 2 9 16409503-16870843 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018525 Approved Supported Nucleus
Cytosol Tissue enhanced 0 endometrium: 44.4;ovary: 39.3;smooth muscle: 47.3 fallopian tube: 19.3 -DEC1 CTS9 ENSG00000173077 Deleted in esophageal cancer 1 9 115141818-115402644 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.5 -RXFP4 GPCR142, GPR100, RLN3R2, RXFPR4 ENSG00000173080 Relaxin/insulin-like family peptide receptor 4 1 155941710-155942949 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 colon: 2.2;duodenum: 1.4;rectum: 2.6 small intestine: 1.1 -HPSE HPA, HPSE1, HSE1 ENSG00000173083 Heparanase 4 83292461-83335153 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055344 Supported Nucleoplasm
Vesicles Tissue enhanced 0 parathyroid gland: 19.6 testis: 10.1 -COQ2 CL640, FLJ26072 ENSG00000173085 Coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 4 83261536-83284914 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA056599, HPA068727 Approved Approved Cytosol Expressed in all adrenal gland: 18.5 -C10orf131 bA690P14.3 ENSG00000173088 Chromosome 10 open reading frame 131 10 95907603-95938723 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA072122 Approved Nucleoli Mixed testis: 10.2 -CCDC63 FLJ35843, ODA5 ENSG00000173093 Coiled-coil domain containing 63 12 110846769-110907535 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA061568 Approved Nucleoplasm
Nuclear bodies
Vesicles Tissue enriched 31 testis: 29.4 skeletal muscle: 0.9 -HSPA6 ENSG00000173110 Heat shock 70kDa protein 6 (HSP70B') 1 161524540-161526910 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017452, HPA028549, HPA052504 Approved Uncertain Nucleoplasm
Vesicles Tissue enhanced 0 placenta: 27.7 spleen: 15.3 -TRMT112 HSPC152, HSPC170, hTrm112, TRM112, TRMT11-2 ENSG00000173113 TRNA methyltransferase 11-2 homolog (S. cerevisiae) 11 64316460-64318084 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039901, HPA040006 Uncertain Approved Nucleus
Microtubules Expressed in all fallopian tube: 305.2 -LRRN3 FIGLER5, FLJ11129, NLRR3 ENSG00000173114 Leucine rich repeat neuronal 3 7 111091006-111125454 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043820, HPA046792 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 adrenal gland: 30.9;cerebral cortex: 31.2;testis: 29.0;thyroid gland: 33.4 lung: 11.6 -KDM2A CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA ENSG00000173120 Lysine (K)-specific demethylase 2A 11 67119269-67258087 Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012272, HPA044251 Supported Approved Nucleus Expressed in all testis: 59.8 -ACSM6 bA310E22.3, C10orf129 ENSG00000173124 Acyl-CoA synthetase medium-chain family member 6 10 95194200-95228928 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044593 Uncertain Tissue enhanced 0 stomach: 1.7 urinary bladder: 0.6 -ADCK5 FLJ35454 ENSG00000173137 AarF domain containing kinase 5 8 144373101-144393242 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025692, HPA028679 Approved Approved Plasma membrane
Cytosol Mixed duodenum: 9.9 -MRPL57 MRP63 ENSG00000173141 Mitochondrial ribosomal protein L57 13 21176645-21179084 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039779, HPA059370 Supported Supported Mitochondria Expressed in all adrenal gland: 21.9 -NOC3L AD24, C10orf117, FAD24, FLJ12820 ENSG00000173145 NOC3-like DNA replication regulator 10 94333226-94362959 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063958, HPA067638, HPA070981 Validated Nucleus
Nucleoli Expressed in all testis: 19.1 -ESRRA ERR1, ERRa, ERRalpha, ESRL1, NR3B1 ENSG00000173153 Estrogen-related receptor alpha 11 64305572-64316743 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053785 Approved Nucleus
Nucleoli fibrillar center
Microtubules
Cytokinetic bridge Expressed in all duodenum: 89.0 -RHOD ARHD, Rho, RhoD, RhoHP1 ENSG00000173156 Ras homolog family member D 11 67056818-67072013 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed esophagus: 37.2 -ADAMTS20 GON-1 ENSG00000173157 ADAM metallopeptidase with thrombospondin type 1 motif, 20 12 43353866-43551921 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027608, HPA027609 Uncertain Not detected placenta: 0.8 -COMMD1 C2orf5, MGC27155, MURR1 ENSG00000173163 Copper metabolism (Murr1) domain containing 1 2 61888724-62147247 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034633, HPA049223 Approved Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 47.6 -RAPH1 ALS2CR18, ALS2CR9, KIAA1681 ENSG00000173166 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 203394345-203535410 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016744, HPA020027 Approved Approved Nuclear bodies
Plasma membrane
Cytosol Expressed in all thyroid gland: 49.6 -MTX1 MTX, MTXN ENSG00000173171 Metaxin 1 1 155208699-155213824 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011543 Uncertain Supported Mitochondria Expressed in all testis: 71.3 -ADCY5 AC5 ENSG00000173175 Adenylate cyclase 5 3 123282296-123449758 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017730, HPA077682 Uncertain Uncertain Intermediate filaments Tissue enhanced 0 heart muscle: 72.9 seminal vesicle: 29.7 -PARP14 KIAA1268, pART8 ENSG00000173193 Poly (ADP-ribose) polymerase family, member 14 3 122680618-122730840 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008846, HPA012063 Supported Validated Cytosol Expressed in all spleen: 51.9 -CYSLTR1 CysLT(1), CysLT1, CYSLT1R ENSG00000173198 Cysteinyl leukotriene receptor 1 X 78271464-78327691 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA010546 Approved Mixed spleen: 15.1 -PARP15 FLJ40597, pART7 ENSG00000173200 Poly (ADP-ribose) polymerase family, member 15 3 122577602-122639047 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA075786 Approved Mitochondria Tissue enhanced 0 lymph node: 56.0;spleen: 61.8;tonsil: 51.1 appendix: 36.8 -CKS1B CKS1, ckshs1 ENSG00000173207 CDC28 protein kinase regulatory subunit 1B 1 154974653-154979249 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003424, HPA030762 Approved Supported Approved Nucleus
Vesicles
Mitochondria
Cytosol Expressed in all lymph node: 86.0 -ABCD2 ALDL1, ALDR, ALDRP ENSG00000173208 ATP-binding cassette, sub-family D (ALD), member 2 12 39550033-39619751 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adipose tissue: 16.7 cervix: 8.4 -AHSA2 DKFZp564C236, Hch1 ENSG00000173209 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) 2 61177418-61191203 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051137 Approved Approved Vesicles
Microtubules
Cytokinetic bridge Expressed in all spleen: 41.9 -ABLIM3 KIAA0843 ENSG00000173210 Actin binding LIM protein family, member 3 5 149141483-149260542 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003245 Approved Approved Nucleoplasm
Plasma membrane
Cell Junctions Tissue enhanced 0 parathyroid gland: 78.1 adipose tissue: 63.4 -MAB21L3 C1orf161, FLJ38716 ENSG00000173212 Mab-21-like 3 (C. elegans) 1 116111755-116135240 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039551, HPA046187 Uncertain Approved Nucleoplasm Tissue enhanced 0 esophagus: 7.5;skin: 7.2 rectum: 1.6 -KIAA1919 MFSD4B, MGC33953 ENSG00000173214 KIAA1919 6 111259348-111271167 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA031784 Approved Uncertain Intermediate filaments Mixed placenta: 5.0 -VANGL1 STB2 ENSG00000173218 VANGL planar cell polarity protein 1 1 115641953-115698224 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025235, CAB076375 Approved Approved Plasma membrane Mixed fallopian tube: 19.2 -GLRX GRX, GRX1 ENSG00000173221 Glutaredoxin (thioltransferase) 5 95751319-95823005 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008634, HPA046431, CAB069419 Approved Supported Plasma membrane
Cytosol Expressed in all kidney: 217.3 -IQCB1 KIAA0036, NPHP5, SLSN5 ENSG00000173226 IQ motif containing B1 3 121769763-121835079 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042028 Supported Microtubules
Cytokinetic bridge
Mitotic spindle Expressed in all testis: 52.2 -SYT12 SRG1 ENSG00000173227 Synaptotagmin XII 11 67006778-67050863 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011006 Uncertain Tissue enriched 7 parathyroid gland: 113.1 cerebral cortex: 17.2 -GOLGB1 GCP, GCP372, giantin, GOLIM1 ENSG00000173230 Golgin B1 3 121663199-121749767 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011008, HPA011555 Supported Validated Golgi apparatus Expressed in all prostate: 42.4 -C11orf86 FLJ22675 ENSG00000173237 Chromosome 11 open reading frame 86 11 66975277-66977004 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA039348 Uncertain Group enriched 7 duodenum: 70.2;small intestine: 72.4 colon: 10.4 -LIPM bA304I5.1, LIPL3 ENSG00000173239 Lipase, family member M 10 88802730-88820546 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 11 skin: 51.5 stomach: 4.8 -GPR151 GALR4, PGR7 ENSG00000173250 G protein-coupled receptor 151 5 146513103-146516190 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected cerebral cortex: 0.2 -DMRT2 ENSG00000173253 Doublesex and mab-3 related transcription factor 2 9 1049858-1057552 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029297 Uncertain Tissue enriched 7 parathyroid gland: 106.9 kidney: 16.0 -ZNF483 KIAA1962, ZKSCAN16, ZSCAN48 ENSG00000173258 Zinc finger protein 483 9 111525159-111577844 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055041 Uncertain Approved Nucleoli Mixed cerebral cortex: 13.0 -PLAC8L1 ENSG00000173261 PLAC8-like 1 5 146084386-146104369 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA074266 Approved Nucleus Tissue enriched 10 testis: 31.1 skin: 3.0 -SLC2A14 GLUT14, SLC2A3P3 ENSG00000173262 Solute carrier family 2 (facilitated glucose transporter), member 14 12 7812512-7891148 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA006539 Approved Approved Plasma membrane Tissue enriched 9 testis: 151.1 breast: 17.2 -GPR137 C11orf4, GPR137A, TM7SF1L1 ENSG00000173264 G protein-coupled receptor 137 11 64270062-64289500 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062871 Uncertain Approved Nucleus
Nucleoli
Actin filaments Expressed in all testis: 147.8 -SNCG BCSG1, persyn, SR ENSG00000173267 Synuclein, gamma (breast cancer-specific protein 1) 10 86958618-86963260 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001452, HPA014404, CAB040581 Supported Approved Approved Golgi apparatus
Plasma membrane Tissue enhanced 0 adipose tissue: 174.4;adrenal gland: 199.0;urinary bladder: 190.7 seminal vesicle: 113.6 -MMRN2 EMILIN3, EndoGlyx-1, FLJ13465 ENSG00000173269 Multimerin 2 10 86935540-86969481 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020741 Approved Approved Vesicles Expressed in all placenta: 101.0 -MZT2A FAM128A, MOZART2A ENSG00000173272 Mitotic spindle organizing protein 2A 2 131464900-131492743 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051758, HPA052623 Approved Supported Centrosome
Cytosol Expressed in all cerebral cortex: 40.6 -TNKS PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1 ENSG00000173273 Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 8 9555914-9782346 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025690 Approved Approved Nucleoplasm
Nuclear membrane Expressed in all testis: 52.7 -ZNF449 FLJ23614, ZSCAN19 ENSG00000173275 Zinc finger protein 449 X 135344796-135363152 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA018079 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 12.0 -ZBTB21 KIAA1227, ZNF295 ENSG00000173276 Zinc finger and BTB domain containing 21 21 41986831-42010387 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024655, HPA031757, HPA031758 Approved Validated Nucleus Mixed adrenal gland: 47.9 -PPP1R3B FLJ14005, GL, PPP1R4 ENSG00000173281 Protein phosphatase 1, regulatory subunit 3B 8 9136255-9151574 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA028731 Approved Approved Cytosol Expressed in all parathyroid gland: 148.6 -OR10K1 ENSG00000173285 Olfactory receptor, family 10, subfamily K, member 1 1 158465562-158466503 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA059125 Uncertain Not detected adipose tissue: 0.0 -GPR148 PGR6 ENSG00000173302 G protein-coupled receptor 148 2 130729070-130730336 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA060527 Uncertain Not detected stomach: 0.4 -STOX2 DKFZp762K222 ENSG00000173320 Storkhead box 2 4 183853431-184023526 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049776, HPA065002 Uncertain Uncertain Nucleoplasm
Actin filaments
Cytosol Tissue enhanced 0 cerebral cortex: 15.4 parathyroid gland: 9.1 -MAP3K11 MEKK11, MLK3, PTK1, SPRK ENSG00000173327 Mitogen-activated protein kinase kinase kinase 11 11 65597755-65615382 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010165 Approved Supported Microtubule organizing center
Cytosol Expressed in all spleen: 56.0 -TRIB1 C8FW, GIG2, TRB1 ENSG00000173334 Tribbles pseudokinase 1 8 125430321-125438405 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063982 Approved Plasma membrane Expressed in all bone marrow: 244.0 -CST9 CLM, CTES7A ENSG00000173335 Cystatin 9 (testatin) 20 23602410-23605876 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029190 Uncertain Tissue enriched 12 breast: 2.2 kidney: 0.1 -KCNK7 K2p7.1 ENSG00000173338 Potassium channel, two pore domain subfamily K, member 7 11 65592855-65595996 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Voltage-gated ion channels Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA077577 Approved Plasma membrane Tissue enriched 7 skin: 53.1 esophagus: 8.0 -SFT2D3 MGC5391 ENSG00000173349 SFT2 domain containing 3 2 127701508-127705242 Predicted membrane proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected epididymis: 0.8 -RP11-330H6.5 ENSG00000173366 3 52221081-52231190 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 lymph node: 3.8 tonsil: 2.2 -C1QB ENSG00000173369 Complement component 1, q subcomponent, B chain 1 22652762-22661538 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052116 Approved Expressed in all spleen: 1460.4 -C1QA ENSG00000173372 Complement component 1, q subcomponent, A chain 1 22636506-22639608 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002350, CAB009823 Supported Uncertain Golgi apparatus
Cytosol Expressed in all spleen: 1187.9 -NDNF C4orf31, FLJ23191 ENSG00000173376 Neuron-derived neurotrophic factor 4 121035613-121073021 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048881 Approved Vesicles Tissue enhanced 0 lung: 160.1;placenta: 85.9 ovary: 52.6 -IQCF1 MGC39725 ENSG00000173389 IQ motif containing F1 3 51894876-51903335 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 573 testis: 57.2 epididymis: 0.0 -OLR1 CLEC8A, LOX-1, SCARE1 ENSG00000173391 Oxidized low density lipoprotein (lectin-like) receptor 1 12 10158301-10172138 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050798 Supported Nucleoplasm
Vesicles
Plasma membrane Group enriched 6 appendix: 42.1;cerebral cortex: 32.8;lung: 146.2;placenta: 159.6 bone marrow: 15.8 -GLIPR1L1 MGC26856 ENSG00000173401 GLI pathogenesis-related 1 like 1 12 75334639-75370560 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042095 Supported Tissue enriched 15 testis: 77.9 epididymis: 5.1 -DAG1 156DAG, A3a, AGRNR, DAG ENSG00000173402 Dystroglycan 1 (dystrophin-associated glycoprotein 1) 3 49468703-49535618 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001960, CAB016353 Supported Approved Vesicles Expressed in all placenta: 108.6 -INSM1 IA-1, IA1 ENSG00000173404 Insulinoma-associated 1 20 20368121-20370949 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adrenal gland: 9.4;stomach: 5.7 duodenum: 3.1 -DAB1 ENSG00000173406 Dab, reelin signal transducer, homolog 1 (Drosophila) 1 56994778-58546734 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032329, HPA052033, HPA067495 Supported Validated Vesicles Tissue enhanced 0 duodenum: 16.4;seminal vesicle: 13.7;small intestine: 25.3 prostate: 7.0 -ARV1 ENSG00000173409 ARV1 homolog, fatty acid homeostasis modulator 1 230978981-231000595 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035709 Approved Approved Vesicles Expressed in all testis: 61.6 -NAA20 dJ1002M8.1, NAT3, NAT5 ENSG00000173418 N(alpha)-acetyltransferase 20, NatB catalytic subunit 20 20017116-20033655 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063344 Supported Cytosol Expressed in all esophagus: 82.9 -CCDC36 CT74, FLJ25320 ENSG00000173421 Coiled-coil domain containing 36 3 49198428-49258104 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045690, HPA069534 Approved Approved Nucleoplasm Tissue enriched 14 testis: 48.6 adipose tissue: 3.5 -RNASE8 RAE2 ENSG00000173431 Ribonuclease, RNase A family, 8 14 21057822-21058455 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 106 salivary gland: 27.4 skin: 0.2 -SAA1 PIG4, SAA, TP53I4 ENSG00000173432 Serum amyloid A1 11 18266174-18269977 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adipose tissue: 3960.2;liver: 1181.8 cervix: 629.4 -MINOS1 C1orf151, FLJ36999, Mic10, MIO10, RP5-1056L3.2 ENSG00000173436 Mitochondrial inner membrane organizing system 1 1 19596977-19629821 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059930 Supported Supported Mitochondria Expressed in all prostate: 13.3 -EHBP1L1 DKFZp762C186, TANGERIN ENSG00000173442 EH domain binding protein 1-like 1 11 65576038-65592650 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039479 Approved Approved Nucleoli
Plasma membrane
Cytosol Mixed skeletal muscle: 88.6 -THAP2 DKFZP564I0422 ENSG00000173451 THAP domain containing, apoptosis associated protein 2 12 71663009-71680639 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA039790 Approved Approved Nucleoplasm
Golgi apparatus Mixed adrenal gland: 35.3 -TMEM196 MGC42090 ENSG00000173452 Transmembrane protein 196 7 19719310-19773598 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043163 Uncertain Tissue enhanced 0 cerebral cortex: 9.2 endometrium: 2.1 -RNF26 MGC2642 ENSG00000173456 Ring finger protein 26 11 119334527-119337313 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027620 Uncertain Approved Nucleoplasm
Vesicles
Cytosol Expressed in all parathyroid gland: 33.3 -PPP1R14B PHI-1, PLCB3N, PNG, SOM172 ENSG00000173457 Protein phosphatase 1, regulatory (inhibitor) subunit 14B 11 64244480-64246941 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053882 Approved Expressed in all skin: 87.4 -RNASE11 C14orf6, RAJ1 ENSG00000173464 Ribonuclease, RNase A family, 11 (non-active) 14 20583559-20609884 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA003724 Uncertain Tissue enriched 7 epididymis: 531.2 testis: 81.5 -SSSCA1 p27 ENSG00000173465 Sjogren syndrome/scleroderma autoantigen 1 11 65570430-65573942 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039789 Uncertain Approved Cytosol Expressed in all cerebral cortex: 52.8 -AGR3 BCMP11, hAG-3, HAG3, PDIA18 ENSG00000173467 Anterior gradient 3, protein disulphide isomerase family member 7 16859405-16881987 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053942 Supported Supported Endoplasmic reticulum Tissue enhanced 0 fallopian tube: 349.7;small intestine: 264.9 rectum: 237.6 -SMARCC1 BAF155, CRACC1, Rsc8, SRG3 ENSG00000173473 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 3 47585272-47782106 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011576, CAB016336, HPA024352, HPA026853 Supported Validated Nucleoplasm Expressed in all prostate: 35.6 -ZNF417 MGC34079 ENSG00000173480 Zinc finger protein 417 19 57900296-57916610 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA042125, HPA043288, HPA056213 Uncertain Uncertain Nucleoplasm Expressed in all epididymis: 59.5 -PTPRM hR-PTPu, PTPRL1, RPTPU ENSG00000173482 Protein tyrosine phosphatase, receptor type, M 18 7566782-8406861 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003891, CAB022442, CAB022443 Supported Approved Plasma membrane Mixed thyroid gland: 91.3 -FKBP2 FKBP-13, PPIase ENSG00000173486 FK506 binding protein 2, 13kDa 11 64241003-64244132 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025561, HPA049405 Supported Approved Plasma membrane Expressed in all epididymis: 392.9 -VEGFB VEGFL, VRF ENSG00000173511 Vascular endothelial growth factor B 11 64234538-64238793 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all adipose tissue: 194.9 -PEAK1 KIAA2002, sgk269 ENSG00000173517 Pseudopodium-enriched atypical kinase 1 15 77100656-77420144 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026313, HPA026517 Approved Mixed spleen: 41.2 -TNFRSF10D CD264, DcR2, TRAILR4, TRUNDD ENSG00000173530 Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 8 23135588-23164030 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA070971 Approved Plasma membrane
Actin filaments Mixed gallbladder: 12.7 -MST1 D3F15S2, DNF15S2, HGFL, MSP, NF15S2 ENSG00000173531 Macrophage stimulating 1 3 49683947-49689501 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA024036 Uncertain Tissue enhanced 0 liver: 143.1 duodenum: 52.7 -TNFRSF10C CD263, DcR1, LIT, TRAILR3, TRID ENSG00000173535 Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8 23084355-23117437 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB025635 Supported Tissue enhanced 0 appendix: 22.4 spleen: 18.5 -GMPPB KIAA1851 ENSG00000173540 GDP-mannose pyrophosphorylase B 3 49716844-49723951 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014657 Uncertain Supported Nucleus Expressed in all thyroid gland: 41.9 -MOB1B MOB4A, MOBKL1A ENSG00000173542 MOB kinase activator 1B 4 70902326-71022449 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047088, HPA071690 Supported Approved Nucleus
Nucleoli
Cytosol Expressed in all kidney: 24.1 -ZNF622 MGC17552, MGC2485, ZPR9 ENSG00000173545 Zinc finger protein 622 5 16451519-16465792 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036514, HPA036515 Uncertain Validated Nucleus
Nucleoli
Golgi apparatus
Cytosol Expressed in all cerebral cortex: 26.6 -CSPG4 HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2 ENSG00000173546 Chondroitin sulfate proteoglycan 4 15 75674322-75712848 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002951, CAB016189, HPA042785, HPA050008 Approved Approved Nucleus
Plasma membrane Mixed adipose tissue: 31.9 -SNX33 MGC32065, SH3PX3, SH3PXD3C, SNX30 ENSG00000173548 Sorting nexin 33 15 75647906-75662301 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040988 Approved Mixed fallopian tube: 26.3 -C2orf70 LOC339778 ENSG00000173557 Chromosome 2 open reading frame 70 2 26562582-26579532 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA062453, HPA069279 Approved Approved Nucleus
Vesicles
Cytosol Group enriched 5 fallopian tube: 11.9;stomach: 4.9;testis: 17.5 thyroid gland: 2.1 -NABP1 DKFZp667M1322, FLJ13624, FLJ22833, hSSB2, MGC111163, OBFC2A, SOSS-B2, SSB2 ENSG00000173559 Nucleic acid binding protein 1 2 191678068-191696659 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054978, HPA067802 Supported Nucleoplasm
Cytosol Mixed appendix: 50.4 -ADGRF3 GPR113, hGPCR37, PGR23 ENSG00000173567 Adhesion G protein-coupled receptor F3 2 26308173-26346817 G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044500 Uncertain Not detected kidney: 0.9 -NLRP13 CLR19.7, NALP13, NOD14, PAN13 ENSG00000173572 NLR family, pyrin domain containing 13 19 55891699-55932336 Predicted intracellular proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level HPA060459 Uncertain Not detected breast: 0.7 -CHD2 DKFZp547I1315, DKFZp686E01200, DKFZp781D1727, FLJ38614 ENSG00000173575 Chromodomain helicase DNA binding protein 2 15 92900189-93028005 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060744, HPA060960 Supported Validated Nucleus Expressed in all bone marrow: 56.0 -XCR1 CCXCR1, GPR5 ENSG00000173578 Chemokine (C motif) receptor 1 3 46017024-46027742 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA013169 Uncertain Tissue enhanced 0 lymph node: 11.0 spleen: 9.3 -CCDC106 HSU79303 ENSG00000173581 Coiled-coil domain containing 106 19 55641062-55653161 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041925, HPA043219 Uncertain Supported Nucleus
Cytosol Expressed in all cerebral cortex: 29.9 -CCR9 CDw199, GPR-9-6, GPR28 ENSG00000173585 Chemokine (C-C motif) receptor 9 3 45886504-45903177 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB006839 Uncertain Group enriched 6 appendix: 1.5;duodenum: 3.9;small intestine: 5.8;spleen: 1.2 lymph node: 0.5 -CEP83 CCDC41, NPHP18, NY-REN-58 ENSG00000173588 Centrosomal protein 83kDa 12 94306449-94459988 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038161 Approved Approved Nucleus
Golgi apparatus Expressed in all testis: 31.4 -SULT1B1 ST1B2 ENSG00000173597 Sulfotransferase family, cytosolic, 1B, member 1 4 69721162-69787961 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002107 Supported Approved Nucleoplasm
Golgi apparatus Group enriched 5 colon: 70.7;duodenum: 101.9;rectum: 69.5;small intestine: 106.2;stomach: 41.6 appendix: 14.6 -NUDT4 DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, KIAA0487 ENSG00000173598 Nudix (nucleoside diphosphate linked moiety X)-type motif 4 12 93377883-93408146 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017593, HPA047027, HPA057684 Uncertain Approved Cytosol Expressed in all ovary: 191.7 -PC PCB ENSG00000173599 Pyruvate carboxylase 11 66848233-66958376 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033742, HPA043922, HPA058765 Uncertain Validated Mitochondria Expressed in all adipose tissue: 63.7 -UGT2A1 ENSG00000173610 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 4 69588417-69653249 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA017261, HPA045108 Uncertain Group enriched 7 kidney: 8.1;liver: 5.5 skin: 0.9 -SCAI C9orf126, FLJ36664, NET40 ENSG00000173611 Suppressor of cancer cell invasion 9 124942608-125143506 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020632 Approved Supported Nucleus
Nuclear membrane Mixed cerebral cortex: 11.8 -GPRC6A bA86F4.3 ENSG00000173612 G protein-coupled receptor, class C, group 6, member A 6 116792085-116829037 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Not detected kidney: 0.7 -NMNAT1 LCA9, NMNAT, PNAT1 ENSG00000173614 Nicotinamide nucleotide adenylyltransferase 1 1 9943428-9985501 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059447 Approved Supported Nucleoplasm
Nuclear bodies Mixed thyroid gland: 12.8 -LRFN4 FIGLER6, MGC3103, SALM3. ENSG00000173621 Leucine rich repeat and fibronectin type III domain containing 4 11 66856647-66860475 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 13.3 -TRAPPC3L bA259P20.2, BET3L, FLJ11180 ENSG00000173626 Trafficking protein particle complex 3-like 6 116494989-116545610 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed spleen: 6.9 -APOBEC4 C1orf169, FLJ25691, MGC26594, RP1-127C7.4 ENSG00000173627 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 1 183646404-183653316 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015636, HPA015637 Approved Group enriched 10 fallopian tube: 19.3;testis: 18.4 lung: 1.9 -SLC19A1 FOLT ENSG00000173638 Solute carrier family 19 (folate transporter), member 1 21 45493572-45544411 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024802 Approved Approved Plasma membrane Mixed duodenum: 22.6 -HSPB7 cvHSP ENSG00000173641 Heat shock 27kDa protein family, member 7 (cardiovascular) 1 16014028-16019594 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027639 Approved Approved Nucleoplasm Tissue enhanced 0 heart muscle: 1486.7;skeletal muscle: 639.8 adipose tissue: 341.6 -RCE1 FACE-2, FACE2, hRCE1, RCE1A, RCE1B ENSG00000173653 Ras converting CAAX endopeptidase 1 11 66842835-66846546 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed skin: 23.4 -UQCRH QCR6, UQCR8 ENSG00000173660 Ubiquinol-cytochrome c reductase hinge protein 1 46303631-46316776 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042574 Supported Expressed in all heart muscle: 459.5 -TAS1R1 GPR70, T1R1, TR1 ENSG00000173662 Taste receptor, type 1, member 1 1 6555181-6579757 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA034579, HPA034580 Approved Tissue enriched 7 testis: 4.2 skin: 0.5 -HES3 bHLHb43 ENSG00000173673 Hes family bHLH transcription factor 3 1 6244192-6245578 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA047927, HPA072697 Uncertain Uncertain Nucleus Not detected testis: 0.1 -EIF1AX eIF-1A, eIF-4C, EIF1A, EIF4C ENSG00000173674 Eukaryotic translation initiation factor 1A, X-linked X 20124518-20141844 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002561 Uncertain Approved Approved Cytosol Expressed in all endometrium: 95.8 -SPDYE2B ENSG00000173678 Speedy/RINGO cell cycle regulator family member E2B 7 102650325-102661398 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA044799, HPA051750 Uncertain Tissue enhanced 0 testis: 4.0 spleen: 2.0 -OR1L1 OR1L2, OR9-C ENSG00000173679 Olfactory receptor, family 1, subfamily L, member 1 9 122661566-122662648 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected urinary bladder: 0.1 -CXorf23 ENSG00000173681 Chromosome X open reading frame 23 X 19912860-19970298 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027215 Approved Approved Nucleoplasm Mixed parathyroid gland: 11.7 -PSMD1 P112, Rpn2, S1 ENSG00000173692 Proteasome 26S subunit, non-ATPase 1 2 231056864-231172827 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021092, HPA036736, HPA036737 Approved Approved Nucleoplasm
Actin filaments Expressed in all parathyroid gland: 200.6 -ADGRG2 EDDM6, GPR64, HE6, TM7LN2 ENSG00000173698 Adhesion G protein-coupled receptor G2 X 18989309-19122637 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001478, HPA050029 Supported Approved Plasma membrane
Cytosol Tissue enriched 6 epididymis: 1469.4 parathyroid gland: 235.5 -SPATA3 TSARG1 ENSG00000173699 Spermatogenesis associated 3 2 230996121-231025055 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA018254 Supported Tissue enriched 445 testis: 159.4 cerebral cortex: 0.3 -MUC13 DRCC1 ENSG00000173702 Mucin 13, cell surface associated 3 124905442-124953819 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045163 Supported Group enriched 6 colon: 307.7;duodenum: 631.7;rectum: 335.1;small intestine: 567.0 appendix: 82.8 -SUSD5 KIAA0527 ENSG00000173705 Sushi domain containing 5 3 33150042-33219215 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052788 Uncertain Uncertain Golgi apparatus
Vesicles Mixed cerebral cortex: 11.0 -HEG1 HEG, KIAA1237 ENSG00000173706 Heart development protein with EGF-like domains 1 3 124965710-125055958 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010952, HPA011559 Approved Approved Vesicles Mixed thyroid gland: 64.8 -WFIKKN2 WFDC20B, WFIKKNRP ENSG00000173714 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 17 50834650-50842348 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 17 ovary: 76.3 testis: 4.4 -C11orf80 FLJ22531 ENSG00000173715 Chromosome 11 open reading frame 80 11 66744451-66843328 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA038932, HPA038933 Approved Approved Centrosome Mixed skin: 48.3 -TOMM20 KIAA0016, MAS20, MOM19, TOM20 ENSG00000173726 Translocase of outer mitochondrial membrane 20 homolog (yeast) 1 235109336-235128936 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005585, HPA011562 Supported Validated Mitochondria Expressed in all cerebral cortex: 230.5 -C1orf100 ENSG00000173728 Chromosome 1 open reading frame 100 1 244352635-244389663 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 52 testis: 70.9 parathyroid gland: 1.3 -AGFG1 HRB, RAB, RIP ENSG00000173744 ArfGAP with FG repeats 1 2 227472152-227561214 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008741 Approved Supported Vesicles Expressed in all testis: 168.4 -STAT5B ENSG00000173757 Signal transducer and activator of transcription 5B 17 42199168-42276707 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004298, HPA042128, HPA049883, HPA051156 Approved Expressed in all endometrium: 70.8 -CD7 GP40, LEU-9, Tp40, TP41 ENSG00000173762 CD7 molecule 17 82314868-82317602 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002594, HPA039079 Supported Tissue enhanced 0 appendix: 44.8;lymph node: 42.1;spleen: 44.0 small intestine: 17.4 -TOPAZ1 C3orf77, FLJ36157 ENSG00000173769 Testis and ovary specific PAZ domain containing 1 3 44241886-44332098 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047431, HPA051034 Uncertain Tissue enriched 65 testis: 6.5 epididymis: 0.0 -CNP ENSG00000173786 2',3'-cyclic nucleotide 3' phosphodiesterase 17 41966741-41977731 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002672, HPA023266, HPA023278, HPA023280, HPA023338 Supported Validated Nucleus
Cytosol Tissue enriched 12 cerebral cortex: 616.5 prostate: 52.3 -JUP CTNNG, DP3, DPIII, PDGB, PKGB ENSG00000173801 Junction plakoglobin 17 41754604-41786931 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002139, HPA032047 Supported Validated Vesicles
Plasma membrane
Cell Junctions Group enriched 6 esophagus: 493.6;skin: 787.3 fallopian tube: 112.6 -HAP1 HAP2, hHLP1, HIP5, HLP ENSG00000173805 Huntingtin-associated protein 1 17 41717742-41734644 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA023394, HPA076992 Uncertain Supported Nucleoli
Cytosol Tissue enhanced 0 cerebral cortex: 11.5;stomach: 13.1 thyroid gland: 6.4 -TDRD12 ECAT8, FLJ13072 ENSG00000173809 Tudor domain containing 12 19 32719753-32829580 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 7 testis: 25.3 epididymis: 3.6 -EIF1 A121, EIF-1, EIF1A, ISO1, SUI1 ENSG00000173812 Eukaryotic translation initiation factor 1 17 41688885-41692668 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all bone marrow: 482.5 -ENDOV FLJ35220 ENSG00000173818 Endonuclease V 17 80415165-80438086 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 22.3 -RNF213 C17orf27, KIAA1554, KIAA1618, MYMY2, NET57 ENSG00000173821 Ring finger protein 213 17 80260866-80398786 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003347, HPA026790 Approved Supported Cytosol Expressed in all parathyroid gland: 66.8 -TIGD3 ENSG00000173825 Tigger transposable element derived 3 11 65354767-65357613 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040016 Uncertain Approved Nucleoplasm
Nuclear membrane Tissue enhanced 0 small intestine: 2.4;testis: 3.9 cerebral cortex: 1.7 -KCNH6 erg2, HERG2, Kv11.2 ENSG00000173826 Potassium channel, voltage gated eag related subfamily H, member 6 17 63523334-63548977 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 kidney: 6.1;prostate: 5.3;small intestine: 5.7 duodenum: 2.3 -MARCH10 FLJ35757, MARCH-X, RNF190 ENSG00000173838 Membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase 17 62701314-62808344 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA023322 Supported Approved Plasma membrane
Cytosol Tissue enriched 7 testis: 145.2 fallopian tube: 20.2 -PLK3 CNK, FNK, PRK ENSG00000173846 Polo-like kinase 3 1 44800225-44805990 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA060318 Approved Mixed gallbladder: 24.4 -NET1 ARHGEF8, NET1A ENSG00000173848 Neuroepithelial cell transforming 1 10 5412551-5458463 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020068 Uncertain Approved Nucleus
Vesicles Expressed in all rectum: 98.1 -DPY19L1 KIAA0877 ENSG00000173852 Dpy-19-like 1 (C. elegans) 7 34928876-35038271 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059139 Uncertain Approved Vesicles Expressed in all testis: 69.2 -PHOSPHO1 ENSG00000173868 Phosphatase, orphan 1 17 49223362-49230766 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053016 Uncertain Tissue enhanced 0 spleen: 23.2;testis: 41.1 bone marrow: 12.4 -ZNF791 FLJ90396 ENSG00000173875 Zinc finger protein 791 19 12610918-12633840 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021537 Uncertain Approved Nucleus Expressed in all thyroid gland: 25.0 -PHC3 EDR3, FLJ12729, FLJ12967, HPH3 ENSG00000173889 Polyhomeotic homolog 3 (Drosophila) 3 170086732-170181749 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039162, HPA062031 Approved Supported Nucleus Expressed in all parathyroid gland: 66.3 -GPR160 GPCR1, GPCR150 ENSG00000173890 G protein-coupled receptor 160 3 170037929-170085403 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA006970 Approved Supported Plasma membrane Tissue enhanced 0 parathyroid gland: 426.5 small intestine: 111.2 -CBX2 CDCA6, MGC10561 ENSG00000173894 Chromobox homolog 2 17 79778132-79787983 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023083 Uncertain Supported Nucleoplasm Tissue enhanced 0 testis: 14.5 placenta: 3.1 -SPTBN2 SCA5 ENSG00000173898 Spectrin, beta, non-erythrocytic 2 11 66685248-66729226 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009844, HPA039293, HPA043529 Supported Supported Cell Junctions
Cytosol Tissue enhanced 0 cerebral cortex: 73.2;skin: 59.4;testis: 48.5 parathyroid gland: 24.2 -GOLIM4 GIMPC, GOLPH4, GPP130, P138 ENSG00000173905 Golgi integral membrane protein 4 3 168008677-168095975 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001677, HPA002315 Supported Validated Golgi apparatus Expressed in all small intestine: 95.7 -KRT28 KRT25D ENSG00000173908 Keratin 28, type I 17 40792203-40799959 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA066890 Supported Tissue enhanced 0 breast: 1.0 testis: 0.4 -RBM4B MGC10871, RBM30, RBM4L, ZCCHC15, ZCCHC21B, ZCRB3B ENSG00000173914 RNA binding motif protein 4B 11 66664998-66677921 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042174, HPA047849 Uncertain Uncertain Nucleoplasm
Cytosol Expressed in all ovary: 36.2 -USMG5 bA792D24.4, DAPIT, MGC14697 ENSG00000173915 Up-regulated during skeletal muscle growth 5 homolog (mouse) 10 103389041-103396466 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044798 Supported Mitochondria Expressed in all heart muscle: 547.4 -HOXB2 HOX2, HOX2H ENSG00000173917 Homeobox B2 17 48540894-48544989 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA047857 Supported Nucleus Tissue enhanced 0 epididymis: 56.0 cervix: 24.6 -C1QTNF1 CTRP1, FLJ90694, GIP, ZSIG37 ENSG00000173918 C1q and tumor necrosis factor related protein 1 17 79022814-79049788 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB025429, HPA051101 Approved Supported Nucleus
Cytosol Tissue enhanced 0 adipose tissue: 154.2 heart muscle: 65.6 -MARCH3 MARCH-III, MGC48332, RNF173 ENSG00000173926 Membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 5 126867714-127030808 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043406 Uncertain Mixed testis: 10.9 -SWSAP1 C19orf39, FLJ35119, SWS1AP1, ZSWIM7AP1 ENSG00000173928 SWIM-type zinc finger 7 associated protein 1 19 11374685-11376951 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052712 Uncertain Mixed spleen: 5.2 -SLCO4C1 OATP-H, OATP4C1, OATPX, SLC21A20 ENSG00000173930 Solute carrier organic anion transporter family, member 4C1 5 102233986-102296549 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 kidney: 42.2 lung: 11.3 -RBM4 LARK, RBM4A, ZCCHC21, ZCRB3A ENSG00000173933 RNA binding motif protein 4 11 66638617-66666682 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042174, HPA047849 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 136.8 -PIFO C1orf88, FLJ23853, pitchfork ENSG00000173947 Primary cilia formation 1 111346288-111353013 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 6 fallopian tube: 268.8 testis: 42.8 -XXYLT1 C3orf21, FLJ35155 ENSG00000173950 Xyloside xylosyltransferase 1 3 195068279-195271167 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed placenta: 15.0 -UBXN2A UBXD4 ENSG00000173960 UBX domain protein 2A 2 23927285-24004909 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA065482, HPA069096 Supported Approved Centrosome Mixed parathyroid gland: 15.7 -RAX2 ARMD6, CORD11, MGC15631, RAXL1 ENSG00000173976 Retina and anterior neural fold homeobox 2 19 3769089-3772221 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052533 Uncertain Tissue enhanced 0 parathyroid gland: 1.1 fallopian tube: 0.7 -LRRC63 RP11-139H14.4 ENSG00000173988 Leucine rich repeat containing 63 13 46211943-46277366 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA039318, HPA039763 Uncertain Approved Golgi apparatus Tissue enhanced 0 epididymis: 3.5;testis: 2.5 cerebral cortex: 1.1 -TCAP CMD1N, LGMD2G, T-cap, TELE, telethonin ENSG00000173991 Titin-cap 17 39664187-39666555 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004591, HPA026477 Supported Group enriched 18 heart muscle: 1974.6;skeletal muscle: 4964.5 esophagus: 196.1 -CCS ENSG00000173992 Copper chaperone for superoxide dismutase 11 66592821-66606019 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008672, HPA040026, HPA044090 Approved Expressed in all parathyroid gland: 21.8 -NRROS ELLP3030, GARPL1, LRRC33, MGC50789, UNQ3030 ENSG00000174004 Negative regulator of reactive oxygen species 3 196639686-196662004 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031586 Uncertain Mixed bone marrow: 19.9 -CEP19 C3orf34, MGC14126 ENSG00000174007 Centrosomal protein 19kDa 3 196706277-196712293 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA047614, HPA071138 Uncertain Supported Centrosome Tissue enhanced 0 testis: 18.0 fallopian tube: 6.5 -KLHL15 KIAA1677 ENSG00000174010 Kelch-like family member 15 X 23983720-24027186 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065730 Uncertain Approved Aggresome
Cytosol Mixed bone marrow: 34.8 -FBXO45 Fbx45 ENSG00000174013 F-box protein 45 3 196568611-196589059 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040730 Uncertain Approved Cytosol Mixed testis: 22.2 -SPERT CBY2, NURIT ENSG00000174015 Spermatid associated 13 45702311-45714559 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039359, HPA040046 Supported Approved Plasma membrane
Cell Junctions Tissue enriched 175 testis: 49.2 fallopian tube: 0.2 -FAM46D CT1.26, CT112, MGC26999 ENSG00000174016 Family with sequence similarity 46, member D X 80335504-80445311 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059362 Uncertain Tissue enriched 55 testis: 6.2 prostate: 0.1 -GNG5 ENSG00000174021 Guanine nucleotide binding protein (G protein), gamma 5 1 84498325-84506565 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB032623, HPA043651 Approved Expressed in all lung: 133.8 -SLC25A30 ENSG00000174032 Solute carrier family 25, member 30 13 45393316-45418455 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045260 Approved Nucleoplasm Expressed in all kidney: 43.2 -C9orf131 MGC41945 ENSG00000174038 Chromosome 9 open reading frame 131 9 35041095-35045991 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA022029 Approved Mitochondria Tissue enriched 12 testis: 61.8 endometrium: 5.1 -CD34 ENSG00000174059 CD34 molecule 1 207880972-207911402 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000018, HPA036722, HPA036723 Supported Approved Nucleus
Plasma membrane
Cell Junctions Expressed in all placenta: 313.8 -CTSF CATSF, CLN13 ENSG00000174080 Cathepsin F 11 66563463-66568841 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002141, HPA031431, HPA055610 Approved Approved Vesicles
Plasma membrane
Cytosol Expressed in all ovary: 140.1 -MSRB3 DFNB74, DKFZp686C1178, FLJ36866 ENSG00000174099 Methionine sulfoxide reductase B3 12 65278643-65488244 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014432 Uncertain Expressed in all smooth muscle: 179.8 -LEMD3 MAN1 ENSG00000174106 LEM domain containing 3 12 65169571-65248327 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025078, HPA076986 Uncertain Supported Nuclear membrane Expressed in all testis: 28.8 -C16orf91 CCSMST1, gs103 ENSG00000174109 Chromosome 16 open reading frame 91 16 1419744-1420800 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Expressed in all cerebral cortex: 16.6 -TLR10 CD290 ENSG00000174123 Toll-like receptor 10 4 38772239-38782990 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 7 appendix: 22.0;lymph node: 52.3;spleen: 35.2;tonsil: 46.8 urinary bladder: 5.7 -TLR1 CD281, KIAA0012, rsc786 ENSG00000174125 Toll-like receptor 1 4 38790677-38856817 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed appendix: 38.2 -TLR6 CD286 ENSG00000174130 Toll-like receptor 6 4 38823715-38856817 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062733 Approved Endoplasmic reticulum Mixed appendix: 14.5 -FAM174A TMEM157, UNQ1912 ENSG00000174132 Family with sequence similarity 174, member A 5 100535305-100586741 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA019539 Approved Approved Golgi apparatus
Cytosol Expressed in all fallopian tube: 51.2 -RGMB DRAGON, FLJ90406 ENSG00000174136 Repulsive guidance molecule family member b 5 98768650-98798643 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016993 Approved Nucleoplasm Mixed cerebral cortex: 39.4 -FAM53A DNTNP ENSG00000174137 Family with sequence similarity 53, member A 4 1617915-1684302 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036452, HPA058138 Supported Uncertain Nucleoplasm Tissue enhanced 0 testis: 17.5 thyroid gland: 7.8 -NWD2 KIAA1239 ENSG00000174145 NACHT and WD repeat domain containing 2 4 37244220-37449465 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046911 Uncertain Tissue enhanced 0 cerebral cortex: 6.2 thyroid gland: 1.4 -CYB561D1 FLJ39035, FLJ44753 ENSG00000174151 Cytochrome b561 family, member D1 1 109494052-109502932 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA027028 Uncertain Mixed skin: 21.4 -GSTA3 ENSG00000174156 Glutathione S-transferase alpha 3 6 52847910-52909685 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004342, HPA048934, HPA053817 Approved Supported Cytosol Group enriched 11 adrenal gland: 56.5;fallopian tube: 100.6;placenta: 31.8;skin: 30.6;testis: 20.2 parathyroid gland: 4.2 -ZDHHC24 ENSG00000174165 Zinc finger, DHHC-type containing 24 11 66520637-66546238 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016619 Approved Approved Vesicles
Cytosol Mixed parathyroid gland: 10.9 -TRMT10C FLJ20432, MRPP1, RG9MTD1 ENSG00000174173 TRNA methyltransferase 10C, mitochondrial RNase P subunit 3 101561862-101566446 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036671 Approved Supported Nucleoplasm
Mitochondria Expressed in all thyroid gland: 25.7 -SELP CD62, CD62P, GMP140, GRMP, PADGEM, PSEL ENSG00000174175 Selectin P (granule membrane protein 140kDa, antigen CD62) 1 169588849-169630193 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002145, HPA002655, HPA005990 Supported Mixed smooth muscle: 20.4 -CTU2 C16orf84, NCS2 ENSG00000174177 Cytosolic thiouridylase subunit 2 homolog (S. pombe) 16 88706463-88715386 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041135, HPA041894 Uncertain Supported Mitochondria Expressed in all cerebral cortex: 10.3 -MGA FLJ12634, KIAA0518, MAD5, MXD5 ENSG00000174197 MGA, MAX dimerization protein 15 41621224-41773081 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042278, HPA058183 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 16.0 -C12orf66 FLJ32549 ENSG00000174206 Chromosome 12 open reading frame 66 12 64186316-64222296 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046743, HPA052855 Uncertain Validated Microtubules
Cytokinetic bridge
Mitotic spindle Expressed in all parathyroid gland: 12.1 -ARL13A ARL13 ENSG00000174225 ADP-ribosylation factor-like 13A X 100969708-100990829 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037377, HPA037378 Uncertain Tissue enriched 7 testis: 7.5 parathyroid gland: 1.1 -SNX31 MGC39715 ENSG00000174226 Sorting nexin 31 8 100572882-100663415 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024284, HPA053466 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced 0 urinary bladder: 33.8 esophagus: 7.3 -PIGG FLJ20265, GPI7, LAS21 ENSG00000174227 Phosphatidylinositol glycan anchor biosynthesis, class G 4 499210-540196 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015997 Uncertain Uncertain Nucleoplasm
Vesicles Expressed in all parathyroid gland: 34.9 -PRPF8 hPrp8, Prp8, PRPC8, RP13, SNRNP220 ENSG00000174231 Pre-mRNA processing factor 8 17 1650629-1684882 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009941, CAB015457 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 92.7 -ADCY6 AC6 ENSG00000174233 Adenylate cyclase 6 12 48766194-48789037 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB018365 Approved Approved Golgi apparatus Mixed adipose tissue: 44.5 -REP15 RAB15EP ENSG00000174236 RAB15 effector protein 12 27696519-27697596 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040448, HPA059868 Approved Tissue enhanced 0 rectum: 71.5;stomach: 82.4 colon: 40.5 -PITPNA PITPN, VIB1A ENSG00000174238 Phosphatidylinositol transfer protein, alpha 17 1517718-1562816 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000528 Uncertain Approved Vesicles
Cytosol Expressed in all cerebral cortex: 118.3 -DDX23 prp28, PRPF28, SNRNP100, U5-100K ENSG00000174243 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 12 48829764-48852842 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038680, HPA039037 Approved Supported Nucleus
Nucleoli Expressed in all fallopian tube: 57.3 -ZNF80 pT17 ENSG00000174255 Zinc finger protein 80 3 114234631-114237578 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA065484 Uncertain Tissue enhanced 0 breast: 6.4 lymph node: 2.7 -ZNHIT2 C11orf5, FON ENSG00000174276 Zinc finger, HIT-type containing 2 11 65116403-65117708 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058066 Uncertain Tissue enhanced 0 testis: 19.0 adrenal gland: 7.7 -EVX2 ENSG00000174279 Even-skipped homeobox 2 2 176077472-176083913 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041576 Uncertain Tissue enhanced 0 prostate: 2.0;seminal vesicle: 2.2;testis: 2.7 cervix: 1.1 -ZBTB4 KAISO-L1, KIAA1538, ZNF903 ENSG00000174282 Zinc finger and BTB domain containing 4 17 7459366-7484263 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008980, HPA064763 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all parathyroid gland: 166.8 -TNK1 ENSG00000174292 Tyrosine kinase, non-receptor, 1 17 7380534-7389774 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012065, HPA056452 Uncertain Approved Cell Junctions Mixed skin: 10.3 -ZHX3 KIAA0395, TIX1 ENSG00000174306 Zinc fingers and homeoboxes 3 20 41178448-41317672 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046498 Supported Nucleoplasm Expressed in all testis: 43.3 -PHLDA3 TIH1 ENSG00000174307 Pleckstrin homology-like domain, family A, member 3 1 201464383-201469237 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027601 Approved Mixed adipose tissue: 61.4 -DIRC1 ENSG00000174325 Disrupted in renal carcinoma 1 2 188734155-188790104 Disease related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056566 Approved Cytosol Not detected epididymis: 0.4 -SLC16A11 FLJ90193, MCT11 ENSG00000174326 Solute carrier family 16, member 11 17 7041630-7043923 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 8.8;parathyroid gland: 11.2 seminal vesicle: 3.8 -SLC16A13 MCT13 ENSG00000174327 Solute carrier family 16, member 13 17 7036075-7040121 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA065245 Supported Golgi apparatus Mixed liver: 15.4 -GLIS1 FLJ36155 ENSG00000174332 GLIS family zinc finger 1 1 53506237-53738106 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA001409 Uncertain Tissue enhanced 0 seminal vesicle: 10.8 prostate: 3.2 -OR2Y1 ENSG00000174339 Olfactory receptor, family 2, subfamily Y, member 1 5 180739042-180740099 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -CHRNA9 NACHRA9 ENSG00000174343 Cholinergic receptor, nicotinic, alpha 9 (neuronal) 4 40335329-40355217 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 fallopian tube: 1.1 cerebral cortex: 0.4 -PODN MGC24995, PCAN, PODOCAN, SLRR5A ENSG00000174348 Podocan 1 53062052-53085502 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 gallbladder: 161.7 ovary: 107.3 -SLC6A19 ENSG00000174358 Solute carrier family 6 (neutral amino acid transporter), member 19 5 1201595-1225117 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037415, HPA043207 Supported Group enriched 21 duodenum: 143.3;kidney: 91.3;small intestine: 160.0 rectum: 6.3 -C11orf45 FLJ43646, MGC35558 ENSG00000174370 Chromosome 11 open reading frame 45 11 128899565-128906035 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039716 Uncertain Approved Cytosol Mixed skin: 7.5 -EXO1 HEX1, hExoI ENSG00000174371 Exonuclease 1 1 241847967-241895148 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053079 Supported Nucleoplasm
Nuclear bodies Mixed bone marrow: 10.7 -RALGAPA1 DKFZp667F074, GARNL1, GRIPE, KIAA0884, RalGAPalpha1, Tulip1 ENSG00000174373 Ral GTPase activating protein, alpha subunit 1 (catalytic) 14 35538352-35809304 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000851 Approved Approved Mitochondria
Cytosol Expressed in all parathyroid gland: 50.5 -LIG4 ENSG00000174405 Ligase IV, DNA, ATP-dependent 13 108207439-108218368 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001334 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Mixed cerebral cortex: 20.1 -TRHR ENSG00000174417 Thyrotropin-releasing hormone receptor 8 109086621-109119584 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level No evidence Evidence at protein level Not detected thyroid gland: 0.2 -GTF2IRD2B ENSG00000174428 GTF2I repeat domain containing 2B 7 75092573-75149817 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA056679, HPA056680 Approved Nucleoplasm Expressed in all ovary: 40.4 -ABRA STARS ENSG00000174429 Actin binding Rho activating protein 8 106759483-106770245 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA017724 Uncertain Group enriched 9 heart muscle: 11.2;skeletal muscle: 49.8 esophagus: 3.3 -ATP2A2 ATP2B, DAR, SERCA2 ENSG00000174437 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 12 110280756-110351093 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062605, HPA067892 Supported Supported Nucleoplasm Expressed in all skeletal muscle: 1006.6 -ZWILCH FLJ10036, KNTC1AP ENSG00000174442 Zwilch kinetochore protein 15 66504959-66550128 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 testis: 96.5 lymph node: 13.7 -RPL4 L4 ENSG00000174444 Ribosomal protein L4 15 66498015-66524532 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034600 Uncertain Supported Nucleoli
Nuclear bodies
Endoplasmic reticulum
Cytosol Expressed in all ovary: 3679.0 -SNAPC5 SNAP19 ENSG00000174446 Small nuclear RNA activating complex, polypeptide 5, 19kDa 15 66490135-66497813 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024379 Uncertain Supported Nucleus Expressed in all testis: 63.6 -STARD6 ENSG00000174448 StAR-related lipid transfer (START) domain containing 6 18 54324358-54357964 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 79 testis: 47.3 thyroid gland: 0.6 -GOLGA6L2 CT105, FLJ36144 ENSG00000174450 Golgin A6 family-like 2 15 23439498-23447234 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 110 testis: 39.5 cerebral cortex: 0.3 -VWC2L ENSG00000174453 Von Willebrand factor C domain containing protein 2-like 2 214411065-214578959 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044815, HPA059414 Uncertain Tissue enriched 31 cerebral cortex: 3.1 epididymis: 0.0 -C12orf76 FLJ40142 ENSG00000174456 Chromosome 12 open reading frame 76 12 110027028-110073686 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039713, HPA042013 Uncertain Approved Plasma membrane
Actin filaments Expressed in all cerebral cortex: 106.1 -ZCCHC12 FLJ16123, PNMA7A, SIZN, SIZN1 ENSG00000174460 Zinc finger, CCHC domain containing 12 X 118823790-118826968 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA031016, HPA034940 Uncertain Approved Nuclear bodies Group enriched 8 endometrium: 165.7;fallopian tube: 182.3;smooth muscle: 201.4 cerebral cortex: 24.4 -CNTNAP2 Caspr2, KIAA0868, NRXN4 ENSG00000174469 Contactin associated protein-like 2 7 146116002-148420998 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002739 Supported Group enriched 11 cerebral cortex: 20.2;prostate: 5.7 breast: 1.2 -GALNTL6 GalNAc-T6L, GALNT17 ENSG00000174473 Polypeptide N-acetylgalactosaminyltransferase-like 6 4 171812254-173041559 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031019 Uncertain Tissue enhanced 0 cerebral cortex: 5.5;testis: 4.8 spleen: 2.1 -LINGO2 LERN3, LRRN6C ENSG00000174482 Leucine rich repeat and Ig domain containing 2 9 27948078-28670286 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA016633, CAB025361 Approved Tissue enhanced 0 endometrium: 11.8;smooth muscle: 12.8 thyroid gland: 4.9 -BBS1 FLJ23590 ENSG00000174483 Bardet-Biedl syndrome 1 11 66510606-66533627 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058283 Uncertain Uncertain Midbody Expressed in all parathyroid gland: 64.4 -DENND4A IRLB, MYCPBP ENSG00000174485 DENN/MADD domain containing 4A 15 65658046-65792293 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065343 Uncertain Approved Nucleus
Nucleoli Expressed in all parathyroid gland: 24.8 -IGDCC3 HsT18880, PUNC ENSG00000174498 Immunoglobulin superfamily, DCC subclass, member 3 15 65327127-65378040 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015246 Approved Group enriched 5 cerebral cortex: 3.3;parathyroid gland: 14.4;placenta: 8.5;testis: 5.2 thyroid gland: 1.5 -GCSAM GCET2, HGAL, MGC40441 ENSG00000174500 Germinal center-associated, signaling and motility 3 112120841-112133305 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002473 Approved Tissue enhanced 0 lymph node: 52.6;tonsil: 55.8 skin: 26.2 -ANKRD36C DKFZp667P0924 ENSG00000174501 Ankyrin repeat domain 36C 2 95836919-95991831 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA051757, HPA057661 Approved Nucleus
Cytosol Tissue enhanced 0 testis: 21.9 bone marrow: 10.7 -SLC26A9 ENSG00000174502 Solute carrier family 26 (anion exchanger), member 9 1 205913048-205943460 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051485 Approved Approved Nucleus
Cell Junctions Tissue enhanced 0 salivary gland: 31.7;stomach: 30.4 lung: 11.4 -MFSD4 DKFZp761N1114, FLJ25004, FLJ34577, UNQ3064 ENSG00000174514 Major facilitator superfamily domain containing 4 1 205568885-205602918 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 kidney: 75.1;stomach: 108.2 cerebral cortex: 50.8 -PELI3 MGC35521 ENSG00000174516 Pellino E3 ubiquitin protein ligase family member 3 11 66466327-66477337 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB033750, HPA038875, HPA062281 Uncertain Approved Nucleus
Nucleoli
Vesicles Mixed parathyroid gland: 24.1 -TTC9B FLJ30373 ENSG00000174521 Tetratricopeptide repeat domain 9B 19 40216058-40218399 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042496 Uncertain Tissue enriched 66 cerebral cortex: 57.7 adrenal gland: 0.8 -MYO1H FLJ37587 ENSG00000174527 Myosin IH 12 109347903-109455523 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039516 Uncertain Tissue enriched 6 testis: 1.8 thyroid gland: 0.3 -TMEM81 HC3107, KVLA2788, MGC75217, UNQ2788 ENSG00000174529 Transmembrane protein 81 1 205083129-205084460 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA052515 Approved Intermediate filaments Mixed testis: 6.7 -MRPL11 ENSG00000174547 Mitochondrial ribosomal protein L11 11 66435075-66466738 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057685 Approved Supported Mitochondria Expressed in all rectum: 26.5 -KLK15 ACO, HSRNASPH, prostinogen ENSG00000174562 Kallikrein-related peptidase 15 19 50825289-50837213 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA019802 Uncertain Tissue enhanced 0 colon: 3.4;salivary gland: 2.4 adrenal gland: 1.8 -IL20RB DIRS1, FNDC6, IL-20R2, MGC34923 ENSG00000174564 Interleukin 20 receptor beta 3 136946230-137011085 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 9 esophagus: 56.8;skin: 166.0 breast: 12.2 -GOLT1A CGI-141, FLJ42654, GOT1, MGC62027, YMR292W ENSG00000174567 Golgi transport 1A 1 204198160-204214092 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 duodenum: 41.5;liver: 78.8;small intestine: 43.2 parathyroid gland: 27.5 -AKIRIN1 C1orf108, FLJ12666 ENSG00000174574 Akirin 1 1 38991223-39006059 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051871 Approved Supported Nucleoplasm
Nuclear membrane Expressed in all testis: 127.4 -NPAS4 bHLHe79, Le-PAS, NXF, PASD10 ENSG00000174576 Neuronal PAS domain protein 4 11 66421004-66426707 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA039255 Uncertain Tissue enhanced 0 cerebral cortex: 4.1;endometrium: 1.9 smooth muscle: 1.5 -MSL2 FLJ10546, KIAA1585, msl-2, MSL2L1, RNF184 ENSG00000174579 Male-specific lethal 2 homolog (Drosophila) 3 136148922-136197241 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003413, HPA048482 Uncertain Approved Cytosol Expressed in all lymph node: 40.4 -ZNF497 FLJ44773 ENSG00000174586 Zinc finger protein 497 19 58354357-58362848 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA047872 Uncertain Approved Nucleus
Cell Junctions Mixed fallopian tube: 10.7 -TRAM1L1 MGC26568 ENSG00000174599 Translocation associated membrane protein 1-like 1 4 117083554-117085576 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044560 Uncertain Approved Mitochondria Mixed cerebral cortex: 14.2 -CMKLR1 RVER1 ENSG00000174600 Chemerin chemokine-like receptor 1 12 108288044-108339341 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047865 Uncertain Tissue enhanced 0 spleen: 49.3 placenta: 40.0 -ANGEL2 Ccr4d, FLJ12793, KIAA0759L ENSG00000174606 Angel homolog 2 (Drosophila) 1 212992182-213015826 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030796 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all cerebral cortex: 17.0 -UGT8 CGT ENSG00000174607 UDP glycosyltransferase 8 4 114598455-114678224 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014405, HPA065785 Approved Approved Mitochondria Tissue enhanced 0 cerebral cortex: 101.6 kidney: 29.8 -KY FLJ33207 ENSG00000174611 Kyphoscoliosis peptidase 3 134603138-134651636 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036492, HPA036668 Uncertain Approved Nucleoplasm Tissue enhanced 0 skin: 11.0 parathyroid gland: 9.2 -IQCK FLJ36575, MGC35048 ENSG00000174628 IQ motif containing K 16 19716456-19858467 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026792, HPA048786 Approved Approved Nuclear speckles
Cytosol Mixed testis: 34.5 -SLCO2A1 MATR1, OATP2A1, PGT, SLC21A2 ENSG00000174640 Solute carrier organic anion transporter family, member 2A1 3 133932696-134052184 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013742 Supported Tissue enhanced 0 seminal vesicle: 113.4 thyroid gland: 71.0 -ZNF266 HZF1 ENSG00000174652 Zinc finger protein 266 19 9412598-9435578 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA026836, HPA054110 Uncertain Validated Nucleus
Vesicles
Rods & Rings Expressed in all epididymis: 115.7 -OR7D4 hg105, OR19-B, OR7D4P ENSG00000174667 Olfactory receptor, family 7, subfamily D, member 4 19 9213850-9214871 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.2 -SLC29A2 DER12, ENT2, HNP36 ENSG00000174669 Solute carrier family 29 (equilibrative nucleoside transporter), member 2 11 66362521-66372214 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018168 Approved Uncertain Nucleoplasm Tissue enhanced 0 skeletal muscle: 36.4 parathyroid gland: 21.8 -BRSK2 C11orf7, PEN11B, STK29 ENSG00000174672 BR serine/threonine kinase 2 11 1389899-1462689 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA073690 Approved Golgi apparatus Tissue enhanced 0 cerebral cortex: 61.8;pancreas: 19.2 testis: 9.5 -B4GAT1 B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, iGNT ENSG00000174684 Beta-1,4-glucuronyltransferase 1 11 66345372-66347692 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015484 Uncertain Tissue enhanced 0 cerebral cortex: 185.7 adrenal gland: 52.7 -TMEM167A FLJ30508, MGC23909, TMEM167 ENSG00000174695 Transmembrane protein 167A 5 83052846-83077863 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all adrenal gland: 62.2 -LEP OB, OBS ENSG00000174697 Leptin 7 128241284-128257628 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010490 Approved Tissue enriched 11 adipose tissue: 321.7 breast: 29.4 -SH3PXD2B FLJ20831, KIAA1295 ENSG00000174705 SH3 and PX domains 2B 5 172325181-172454523 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036471 Approved Approved Nucleus
Nucleoli fibrillar center
Plasma membrane Mixed cervix: 35.4 -KIAA1551 C12orf35, FLJ10652, FLJ20696, UTA2-1 ENSG00000174718 KIAA1551 12 31959370-31993107 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013816, HPA015622 Approved Supported Nucleoli
Intermediate filaments
Cytosol Expressed in all ovary: 90.6 -LARP7 DKFZP564K112, HDCMA18P, PIP7S ENSG00000174720 La ribonucleoprotein domain family, member 7 4 112636964-112657592 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026842, HPA027930 Approved Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 58.3 -FGFBP3 C10orf13, MGC39320 ENSG00000174721 Fibroblast growth factor binding protein 3 10 91906589-91909483 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053943 Uncertain Tissue enriched 8 cerebral cortex: 19.6 thyroid gland: 2.5 -NR1D2 BD73, EAR-1r, Hs.37288, HZF2, RVR ENSG00000174738 Nuclear receptor subfamily 1, group D, member 2 3 23945260-23980618 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA053868, HPA054798 Approved Approved Nucleoplasm Expressed in all thyroid gland: 89.9 -PABPC5 PABP5 ENSG00000174740 Poly(A) binding protein, cytoplasmic 5 X 91434595-91438584 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000164, HPA000165 Approved Tissue enhanced 0 ovary: 13.3 adrenal gland: 9.7 -BRMS1 DKFZP564A063 ENSG00000174744 Breast cancer metastasis suppressor 1 11 66337333-66345125 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010824, HPA019637 Approved Approved Centrosome Expressed in all skin: 36.3 -RPL15 EC45, L15, RPL10, RPLY10, RPYL10 ENSG00000174748 Ribosomal protein L15 3 23916545-23923692 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 3471.4 -C4orf32 FLJ39370 ENSG00000174749 Chromosome 4 open reading frame 32 4 112145397-112195256 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062443, HPA069294 Approved Approved Golgi apparatus Mixed adipose tissue: 19.3 -HRAS HRAS1 ENSG00000174775 Harvey rat sarcoma viral oncogene homolog 11 532242-537287 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002015, HPA049830 Approved Expressed in all cerebral cortex: 25.0 -WDR49 FLJ33620 ENSG00000174776 WD repeat domain 49 3 167478684-167653983 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036225, HPA036226 Uncertain Tissue enhanced 0 fallopian tube: 18.2 small intestine: 5.1 -SRP72 ENSG00000174780 Signal recognition particle 72kDa 4 56466915-56503680 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034621 Approved Expressed in all thyroid gland: 88.8 -PCP2 GPSM4, MGC41903 ENSG00000174788 Purkinje cell protein 2 19 7631611-7633748 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057428 Approved Nuclear speckles
Vesicles Tissue enriched 9 testis: 72.6 skin: 8.1 -RIN1 ENSG00000174791 Ras and Rab interactor 1 11 66330242-66336840 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035491 Uncertain Approved Nucleus
Nuclear membrane Tissue enhanced 0 skin: 19.3 cerebral cortex: 5.2 -C4orf26 FLJ23657 ENSG00000174792 Chromosome 4 open reading frame 26 4 75556048-75565885 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 12 placenta: 5.8 cerebral cortex: 0.5 -THAP6 MGC30052 ENSG00000174796 THAP domain containing 6 4 75513946-75550473 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA035767 Uncertain Approved Nucleus
Centrosome Expressed in all testis: 44.1 -CEP135 CEP4, FLJ13621, KIAA0635 ENSG00000174799 Centrosomal protein 135kDa 4 55948871-56033363 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed endometrium: 13.0 -FZD4 CD344, EVR1 ENSG00000174804 Frizzled class receptor 4 11 86945679-86955391 CD markers, Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042328, HPA074833 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 adipose tissue: 127.0 seminal vesicle: 42.1 -CD248 CD164L1, TEM1 ENSG00000174807 CD248 molecule, endosialin 11 66314487-66317044 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051856 Uncertain Approved Nucleoplasm
Plasma membrane Tissue enhanced 0 adipose tissue: 136.1 placenta: 96.3 -BTC ENSG00000174808 Betacellulin 4 74744759-74794686 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed skin: 15.4 -PDZK1 NHERF3, PDZD1 ENSG00000174827 PDZ domain containing 1 1 145670852-145708148 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005755, HPA006155, CAB008971 Supported Supported Endoplasmic reticulum
Vesicles Tissue enhanced 0 kidney: 557.9;small intestine: 129.6 duodenum: 70.9 -ADGRE1 EMR1, TM7LN3 ENSG00000174837 Adhesion G protein-coupled receptor E1 19 6887566-6940459 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052809 Uncertain Tissue enhanced 0 appendix: 10.2;spleen: 20.1 lung: 6.8 -DENND6A AFI1A, FAM116A, FLJ34969 ENSG00000174839 DENN/MADD domain containing 6A 3 57625457-57693089 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062618, HPA069725, HPA071711 Approved Supported Vesicles Expressed in all ovary: 25.5 -PDE12 2'-PDE, DKFZp667B1218 ENSG00000174840 Phosphodiesterase 12 3 57556276-57566844 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043171 Approved Expressed in all parathyroid gland: 15.7 -GLMN FAP48, FKBPAP, GLML, GVM, VMGLOM ENSG00000174842 Glomulin, FKBP associated protein 1 92246402-92298987 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031446, HPA031448 Approved Approved Nucleoplasm
Cytosol Mixed testis: 15.2 -DNAH12 DHC3, DLP12, DNAH12L, DNAH7L, Dnahc3, DNHD2, FLJ40427, FLJ44290, hdhc3, HL-19 ENSG00000174844 Dynein, axonemal, heavy chain 12 3 57293699-57544344 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA037493, HPA058203, HPA061365 Supported Tissue enhanced 0 fallopian tube: 16.0;testis: 11.0 lung: 2.7 -YIF1A 54TM, FinGER7, YIF1, YIF1P ENSG00000174851 Yip1 interacting factor homolog A (S. cerevisiae) 11 66284580-66289170 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014840 Approved Supported Golgi apparatus
Vesicles
Microtubule organizing center Expressed in all thyroid gland: 61.2 -CNIH2 CNIH-2, Cnil, MGC50896 ENSG00000174871 Cornichon family AMPA receptor auxiliary protein 2 11 66278190-66285301 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 11 cerebral cortex: 53.0 adrenal gland: 4.6 -AMY1B AMY1 ENSG00000174876 Amylase, alpha 1B (salivary) 1 103687415-103696680 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045394, HPA045399, HPA046980 Supported Tissue enriched 15 salivary gland: 1847.5 cervix: 125.1 -NLRP6 CLR11.4, NALP6, PAN3, PYPAF5 ENSG00000174885 NLR family, pyrin domain containing 6 11 278365-285359 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043681, HPA048500 Supported Group enriched 13 duodenum: 40.5;small intestine: 41.0 appendix: 3.1 -NDUFA11 B14.7 ENSG00000174886 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa 19 5891276-5904006 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072209 Uncertain Mitochondria Expressed in all heart muscle: 298.5 -RSRC1 BM-011, MGC12197, SFRS21, SRrp53 ENSG00000174891 Arginine/serine-rich coiled-coil 1 3 158105855-158545730 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044792 Supported Approved Nuclear speckles Expressed in all cerebral cortex: 39.1 -CATSPERD MGC39581, TMEM146 ENSG00000174898 Catsper channel auxiliary subunit delta 19 5720677-5778734 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024056 Supported Tissue enriched 160 testis: 15.9 epididymis: 0.0 -PQLC2L C3orf55 ENSG00000174899 PQ loop repeat containing 2-like 3 157543246-157677749 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054395 Uncertain Approved Nucleoplasm
Nuclear bodies Tissue enhanced 0 adipose tissue: 21.5;thyroid gland: 16.0 breast: 6.0 -RAB1B ENSG00000174903 RAB1B, member RAS oncogene family 11 66268533-66277492 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010225, HPA056141 Approved Supported Endoplasmic reticulum
Golgi apparatus Expressed in all parathyroid gland: 181.5 -OR9G1 OR9G5 ENSG00000174914 Olfactory receptor, family 9, subfamily G, member 1 11 56700388-56701305 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -PTDSS2 PSS2 ENSG00000174915 Phosphatidylserine synthase 2 11 448268-491399 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038928, HPA038929 Approved Expressed in all testis: 25.4 -C19orf70 P117, QIL1 ENSG00000174917 Chromosome 19 open reading frame 70 19 5678421-5680896 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042672 Approved Supported Nucleoplasm
Mitochondria Expressed in all cerebral cortex: 75.3 -C3orf33 AC3-33, FLJ31139 ENSG00000174928 Chromosome 3 open reading frame 33 3 155762617-155806351 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037663 Uncertain Approved Nucleoplasm
Cytosol Mixed thyroid gland: 14.4 -OR5M3 ENSG00000174937 Olfactory receptor, family 5, subfamily M, member 3 11 56469574-56470497 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -SEZ6L2 FLJ90517, PSK-1 ENSG00000174938 Seizure related 6 homolog (mouse)-like 2 16 29871159-29899547 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064471 Approved Tissue enhanced 0 cerebral cortex: 82.7;parathyroid gland: 57.3 adrenal gland: 30.8 -ASPHD1 ENSG00000174939 Aspartate beta-hydroxylase domain containing 1 16 29900375-29919864 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045175 Uncertain Tissue enhanced 0 cerebral cortex: 53.7 gallbladder: 11.9 -OR5R1 OR5R1P ENSG00000174942 Olfactory receptor, family 5, subfamily R, member 1 (gene/pseudogene) 11 56417258-56418232 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA049992 Uncertain Not detected adipose tissue: 0.0 -KCTD13 FKSG86, PDIP1, POLDIP1 ENSG00000174943 Potassium channel tetramerization domain containing 13 16 29905012-29927035 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043524 Supported Supported Nucleus
Nuclear bodies Mixed testis: 13.9 -P2RY14 GPR105, KIAA0001 ENSG00000174944 Purinergic receptor P2Y, G-protein coupled, 14 3 151212117-151278467 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB022646 Uncertain Tissue enhanced 0 placenta: 45.4 esophagus: 23.4 -AMZ1 KIAA1950 ENSG00000174945 Archaelysin family metallopeptidase 1 7 2679522-2775500 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA020233 Uncertain Tissue enhanced 0 cerebral cortex: 4.0 endometrium: 1.6 -GPR171 H963 ENSG00000174946 G protein-coupled receptor 171 3 151197832-151203201 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA062429 Approved Tissue enhanced 0 appendix: 30.7 lymph node: 21.8 -GPR149 IEDA, PGR10 ENSG00000174948 G protein-coupled receptor 149 3 154337672-154429715 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018020 Uncertain Tissue enriched 6 seminal vesicle: 2.9 testis: 0.4 -CD164L2 ENSG00000174950 CD164 sialomucin-like 2 1 27379176-27383380 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062915 Approved Tissue enhanced 0 fallopian tube: 45.7 skin: 10.7 -FUT1 H, HSC ENSG00000174951 Fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 19 48748011-48755390 Blood group antigen proteins, Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed stomach: 7.1 -DHX36 DDX36, KIAA1488, MLEL1 ENSG00000174953 DEAH (Asp-Glu-Ala-His) box polypeptide 36 3 154272546-154324497 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035399 Approved Supported Nucleus
Cytosol Expressed in all testis: 63.0 -OR5J2 ENSG00000174957 Olfactory receptor, family 5, subfamily J, member 2 11 56176618-56177556 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA059466 Uncertain Not detected epididymis: 0.0 -ZIC4 ENSG00000174963 Zic family member 4 3 147386046-147406860 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030194 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 cerebral cortex: 4.3;skin: 1.4 testis: 0.7 -OR10AG1 ENSG00000174970 Olfactory receptor, family 10, subfamily AG, member 1 11 55967558-55968463 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -OR4S2 OR4S2P, OST725 ENSG00000174982 Olfactory receptor, family 4, subfamily S, member 2 11 55650904-55651839 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -FBXW8 FBW6, FBW8, FBX29, FBXO29 ENSG00000174989 F-box and WD repeat domain containing 8 12 116910956-117031148 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038850, HPA038851 Supported Supported Cytosol Expressed in all thyroid gland: 16.2 -CA5A CA5, CAV, CAVA ENSG00000174990 Carbonic anhydrase VA, mitochondrial 16 87881546-87936529 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed liver: 1.4 -ZG16 hZG16, JCLN, JCLN1, ZG16A ENSG00000174992 Zymogen granule protein 16 16 29778240-29782973 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052066, HPA052512 Supported Group enriched 6 colon: 369.7;rectum: 511.8;small intestine: 123.6 duodenum: 59.3 -KLC2 FLJ12387 ENSG00000174996 Kinesin light chain 2 11 66257294-66267860 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040416, HPA040434 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all cerebral cortex: 64.0 -SLC22A1 OCT1 ENSG00000175003 Solute carrier family 22 (organic cation transporter), member 1 6 160121789-160158718 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029846 Approved Tissue enriched 252 liver: 286.8 gallbladder: 1.1 -TEX36 bA383C5.1, C10orf122 ENSG00000175018 Testis expressed 36 10 125576522-125683144 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 55 testis: 47.2 smooth muscle: 0.8 -CTBP2 ribeye ENSG00000175029 C-terminal binding protein 2 10 124984317-125161170 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023559, HPA023564, CAB031916, HPA044971 Approved Approved Cytosol Expressed in all thyroid gland: 90.3 -CHST2 C6ST ENSG00000175040 Carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 3 143119331-143124014 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013620 Supported Golgi apparatus Mixed spleen: 15.5 -ZDHHC14 FLJ20984, NEW1CP ENSG00000175048 Zinc finger, DHHC-type containing 14 6 157381133-157678146 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046033, HPA063754 Uncertain Approved Nucleoli
Mitochondria Mixed endometrium: 12.3 -ATR FRP1, MEC1, SCKL, SCKL1 ENSG00000175054 ATR serine/threonine kinase 3 142449235-142578826 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054320 Supported Nucleoplasm
Golgi apparatus Mixed parathyroid gland: 15.2 -UBE2C UBCH10 ENSG00000175063 Ubiquitin-conjugating enzyme E2C 20 45812576-45816957 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011464, HPA034569, CAB035990, HPA054975 Approved Validated Plasma membrane
Cytosol Mixed tonsil: 59.1 -DSG4 CDHF13, LAH ENSG00000175065 Desmoglein 4 18 31376777-31414912 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059456 Supported Not detected testis: 0.8 -GK5 MGC40579 ENSG00000175066 Glycerol kinase 5 (putative) 3 142157527-142225607 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042606, HPA057998 Approved Approved Nucleoplasm
Cytosol Mixed prostate: 12.7 -VCPIP1 DUBA3, FLJ23132, KIAA1850, VCIP135 ENSG00000175073 Valosin containing protein (p97)/p47 complex interacting protein 1 8 66628487-66667217 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023932 Uncertain Approved Plasma membrane Mixed bone marrow: 13.2 -RTP1 MGC35450, Z3CXXC1 ENSG00000175077 Receptor (chemosensory) transporter protein 1 3 187197486-187201465 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 1.3 testis: 0.7 -DES CMD1I, CSM1, CSM2 ENSG00000175084 Desmin 2 219418377-219426739 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000034, HPA018803 Supported Supported Intermediate filaments Tissue enhanced 0 heart muscle: 3865.2;skeletal muscle: 5463.5;smooth muscle: 3556.9 seminal vesicle: 3096.2 -PDIK1L CLIK1L ENSG00000175087 PDLIM1 interacting kinase 1 like 1 26111165-26125543 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064157 Supported Nucleoplasm Expressed in all thyroid gland: 27.3 -SPSB4 SSB-4 ENSG00000175093 SplA/ryanodine receptor domain and SOCS box containing 4 3 141051402-141148611 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA073015 Approved Nucleoplasm
Plasma membrane Tissue enhanced 0 cerebral cortex: 1.3;spleen: 1.5;testis: 2.4 pancreas: 1.2 -RAG2 ENSG00000175097 Recombination activating gene 2 11 36575574-36598279 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 22 thyroid gland: 40.0 testis: 1.8 -TRAF6 RNF85 ENSG00000175104 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 11 36487027-36510272 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004605, HPA019805, HPA020599 Approved Supported Nucleoli
Mitochondria Expressed in all thyroid gland: 16.2 -ZNF654 FLJ10997, FLJ21142 ENSG00000175105 Zinc finger protein 654 3 88139104-88144665 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036172, HPA036173 Uncertain Approved Nucleus
Microtubules Mixed testis: 12.3 -TVP23C FAM18B2, MGC8763 ENSG00000175106 Trans-golgi network vesicle protein 23 homolog C (S. cerevisiae) 17 15502264-15563595 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA019585, HPA065603 Uncertain Validated Golgi apparatus Mixed thyroid gland: 10.3 -MRPS22 C3orf5, GIBT, GK002, MRP-S22 ENSG00000175110 Mitochondrial ribosomal protein S22 3 139005806-139357223 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006083, HPA007830 Supported Supported Mitochondria Expressed in all adrenal gland: 69.8 -PACS1 FLJ10209, KIAA1175 ENSG00000175115 Phosphofurin acidic cluster sorting protein 1 11 66070363-66244747 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038914 Approved Approved Microtubules
Cytosol Expressed in all testis: 74.1 -WFDC5 dJ211D12.5, WAP1 ENSG00000175121 WAP four-disulfide core domain 5 20 45109452-45115172 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 36 skin: 469.0 breast: 13.0 -MARCKSL1 F52, MacMARCKS, MLP, MLP1 ENSG00000175130 MARCKS-like 1 1 32333832-32336379 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020787, HPA030528 Approved Supported Nucleoplasm
Actin filaments
Cytosol Expressed in all cerebral cortex: 316.0 -SH3BP5L KIAA1720 ENSG00000175137 SH3-binding domain protein 5-like 1 248810446-248826633 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038067, HPA038068 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all cerebral cortex: 19.8 -OR2T1 OR1-25 ENSG00000175143 Olfactory receptor, family 2, subfamily T, member 1 1 248405995-248407104 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA063064 Uncertain Not detected adipose tissue: 0.0 -YPEL2 FKSG4 ENSG00000175155 Yippee-like 2 17 59331689-59401729 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA030501, HPA045621 Uncertain Expressed in all cerebral cortex: 26.3 -CADM2 IGSF4D, Necl-3, NECL3, SynCAM2 ENSG00000175161 Cell adhesion molecule 2 3 84958981-86074429 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA010024 Supported Tissue enriched 14 cerebral cortex: 86.4 seminal vesicle: 6.2 -ABO A3GALNT, A3GALT1 ENSG00000175164 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 9 133250401-133275214 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enriched 9 small intestine: 12.9 rectum: 1.4 -PSMD2 MGC14274, P97, Rpn1, S2, TRAP2 ENSG00000175166 Proteasome 26S subunit, non-ATPase 2 3 184298709-184309054 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045192 Approved Expressed in all testis: 163.1 -FAM182B ENSG00000175170 Family with sequence similarity 182, member B 20 25763466-25868225 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB034235, HPA050100 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 11.8 fallopian tube: 6.7 -PPM1E CaMKP-N, KIAA1072, POPX1, PP2CH ENSG00000175175 Protein phosphatase, Mg2+/Mn2+ dependent, 1E 17 58755869-58985176 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018462, HPA019263 Approved Supported Nucleus
Nucleoli Group enriched 5 adrenal gland: 7.3;cerebral cortex: 20.5;testis: 12.1 fallopian tube: 2.4 -FAM131A C3orf40, MGC21688 ENSG00000175182 Family with sequence similarity 131, member A 3 184335926-184346275 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042800 Uncertain Approved Nucleus
Nucleoli Expressed in all cerebral cortex: 101.5 -CSRP2 CRP2, LMO5, SmLIM ENSG00000175183 Cysteine and glycine-rich protein 2 12 76858715-76879060 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045617 Uncertain Mixed placenta: 113.7 -INHBC ENSG00000175189 Inhibin, beta C 12 57434760-57450828 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 42 liver: 85.8 testis: 2.0 -PARL PRO2207, PSARL, PSARL1, RHBDS1 ENSG00000175193 Presenilin associated, rhomboid-like 3 183829385-183884933 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019545 Approved Supported Mitochondria Expressed in all epididymis: 71.5 -DDIT3 CHOP, CHOP10, GADD153 ENSG00000175197 DNA-damage-inducible transcript 3 12 57516588-57520517 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA058416, HPA068416 Approved Approved Nucleoplasm Expressed in all thyroid gland: 263.1 -PCCA ENSG00000175198 Propionyl CoA carboxylase, alpha polypeptide 13 100089015-100530435 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041716, HPA047792 Supported Expressed in all epididymis: 259.8 -HIGD2B HIGD2BP ENSG00000175202 HIG1 hypoxia inducible domain family, member 2B 15 72675783-72686149 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA019016, HPA042715 Uncertain Tissue enriched 14 testis: 6.7 epididymis: 0.4 -DCTN2 DCTN-50, RBP50 ENSG00000175203 Dynactin 2 (p50) 12 57530102-57547331 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039715, HPA040040 Approved Validated Centrosome Expressed in all cerebral cortex: 163.5 -NPPA ANP, PND ENSG00000175206 Natriuretic peptide A 1 11845709-11848345 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058269 Supported Supported Tissue enriched 1175 heart muscle: 26555.9 epididymis: 22.5 -ZNF408 FLJ12827 ENSG00000175213 Zinc finger protein 408 11 46700818-46705912 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017892 Uncertain Approved Microtubule organizing center
Cytosol Expressed in all bone marrow: 8.3 -CTDSP2 OS4, PSR2, SCP2 ENSG00000175215 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 12 57819927-57846739 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052607 Uncertain Uncertain Nucleoplasm Expressed in all lung: 170.4 -CKAP5 ch-TOG, KIAA0097, TOG, TOGp ENSG00000175216 Cytoskeleton associated protein 5 11 46743048-46846308 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039377, HPA040375 Supported Approved Nucleoli
Plasma membrane
Cytosol Expressed in all cerebral cortex: 66.4 -ARHGAP1 CDC42GAP, p50rhoGAP, RhoGAP ENSG00000175220 Rho GTPase activating protein 1 11 46677080-46700615 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004689, HPA008285 Approved Approved Supported Vesicles Expressed in all smooth muscle: 114.7 -MED16 DRIP92, THRAP5, TRAP95 ENSG00000175221 Mediator complex subunit 16 19 867630-893218 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030685, HPA046495 Uncertain Approved Nucleoli Expressed in all cerebral cortex: 29.0 -ATG13 KIAA0652 ENSG00000175224 Autophagy related 13 11 46617527-46674818 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039350 Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 111.4 -GAL3ST3 GAL3ST2 ENSG00000175229 Galactose-3-O-sulfotransferase 3 11 66041952-66049180 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 4.3;endometrium: 4.3;smooth muscle: 4.7;thyroid gland: 8.2 seminal vesicle: 2.4 -C1orf127 FLJ37118 ENSG00000175262 Chromosome 1 open reading frame 127 1 10946471-10982037 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA027654 Uncertain Tissue enhanced 0 skeletal muscle: 5.7 stomach: 2.1 -CHST1 C6ST, KSGal6ST ENSG00000175264 Carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 11 45648877-45665622 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 49.1;parathyroid gland: 18.8 thyroid gland: 9.8 -GOLGA8A GM88, GOLGIN-67 ENSG00000175265 Golgin A8 family, member A 15 34379068-34437466 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051808 Approved Golgi apparatus
Cytosol Mixed skin: 41.1 -VWA3A FLJ40941, FLJ46765 ENSG00000175267 Von Willebrand factor A domain containing 3A 16 22092538-22156966 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041696, HPA042044 Uncertain Tissue enhanced 0 fallopian tube: 52.4 lung: 11.6 -TP53I11 PIG11 ENSG00000175274 Tumor protein p53 inducible protein 11 11 44885903-44951306 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059727, HPA061276 Uncertain Supported Endoplasmic reticulum
Golgi apparatus Expressed in all adipose tissue: 58.0 -APITD1 CENP-S, CENPS, FAAP16, MHF1 ENSG00000175279 Apoptosis-inducing, TAF9-like domain 1 1 10430443-10442809 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 84.0 -DOLK DK1, KIAA1094, TMEM15 ENSG00000175283 Dolichol kinase 9 128945530-128947619 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054813 Uncertain Nucleus
Cytosol Mixed parathyroid gland: 24.3 -PHYHD1 MGC16638 ENSG00000175287 Phytanoyl-CoA dioxygenase domain containing 1 9 128920895-128942041 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012115 Approved Nuclear speckles Expressed in all cervix: 59.4 -CATSPER1 CATSPER ENSG00000175294 Cation channel, sperm associated 1 11 66016752-66026517 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 31 testis: 20.4 lung: 0.6 -CCNE2 CYCE2 ENSG00000175305 Cyclin E2 8 94879770-94896678 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007825, CAB019374 Approved Mixed testis: 27.0 -PHYKPL AGXT2L2, MGC15875 ENSG00000175309 5-phosphohydroxy-L-lysine phospho-lyase 5 178208497-178232791 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036461, HPA063608 Approved Approved Mitochondria Expressed in all rectum: 35.8 -ANKS4B FLJ38819, HARP ENSG00000175311 Ankyrin repeat and sterile alpha motif domain containing 4B 16 21233665-21253845 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043523 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 duodenum: 18.6;rectum: 15.9;small intestine: 26.3 colon: 13.9 -CST6 ENSG00000175315 Cystatin E/M 11 66011841-66013505 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019316, HPA044963 Supported Approved Plasma membrane
Cytosol Tissue enriched 9 skin: 213.3 breast: 24.7 -GRAMD2 ENSG00000175318 GRAM domain containing 2 15 72159807-72197785 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029435 Uncertain Approved Nucleoli
Nuclear speckles
Cytosol Tissue enhanced 0 epididymis: 45.7;placenta: 69.4 lung: 23.6 -ZNF519 FLJ36809, HsT2362 ENSG00000175322 Zinc finger protein 519 18 14057457-14132490 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA028982 Uncertain Approved Nucleoli Mixed endometrium: 4.0 -LSM1 CASM, YJL124C ENSG00000175324 LSM1 homolog, mRNA degradation associated 8 38163321-38176730 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024601 Supported Vesicles
Cytosol Expressed in all placenta: 35.5 -PROP1 ENSG00000175325 PROP paired-like homeobox 1 5 177992235-177996242 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -ISX RAXLX ENSG00000175329 Intestine-specific homeobox 22 35066136-35087387 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA060328 Approved Supported Nucleoplasm
Nuclear bodies Group enriched 37 colon: 27.9;duodenum: 38.5;rectum: 28.6;small intestine: 30.3 smooth muscle: 0.8 -BANF1 BAF ENSG00000175334 Barrier to autointegration factor 1 11 66002079-66004149 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032896, HPA039242 Supported Supported Nucleoplasm
Cytosol Expressed in all fallopian tube: 237.4 -APOF ENSG00000175336 Apolipoprotein F 12 56360569-56362823 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 117 liver: 219.8 prostate: 1.8 -CHRNA7 ENSG00000175344 Cholinergic receptor, nicotinic, alpha 7 (neuronal) 15 32030488-32172521 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA029422, CAB033624 Supported Tissue enhanced 0 adrenal gland: 6.0;small intestine: 6.0 stomach: 3.6 -TMEM9B C11orf15 ENSG00000175348 TMEM9 domain family, member B 11 8947294-8965011 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037784 Uncertain Expressed in all thyroid gland: 129.2 -NRIP3 C11orf14 ENSG00000175352 Nuclear receptor interacting protein 3 11 8980576-9004049 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040573, HPA058827 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 36.6;testis: 55.5 adrenal gland: 13.3 -PTPN2 PTPT, TC-PTP, TCELLPTP, TCPTP ENSG00000175354 Protein tyrosine phosphatase, non-receptor type 2 18 12785478-12929643 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015004, HPA046176 Supported Validated Nucleoplasm Expressed in all lymph node: 53.2 -SCUBE2 Cegb1, Cegf1, FLJ16792 ENSG00000175356 Signal peptide, CUB domain, EGF-like 2 11 9020391-9138114 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA006353, HPA029871 Uncertain Mixed epididymis: 62.1 -EIF1AD haponin, MGC11102 ENSG00000175376 Eukaryotic translation initiation factor 1A domain containing 11 65996545-66002176 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054991, HPA058735 Uncertain Supported Nucleoplasm
Vesicles Expressed in all parathyroid gland: 34.3 -SMAD2 JV18-1, MADH2, MADR2 ENSG00000175387 SMAD family member 2 18 47808957-47931146 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025507, HPA067203, CAB073546 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all thyroid gland: 126.1 -EIF3F eIF3-epsilon, eIF3-p47, eIF3f, EIF3S5 ENSG00000175390 Eukaryotic translation initiation factor 3, subunit F 11 7970251-8001862 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049250 Approved Approved Nucleoli
Cytosol Expressed in all ovary: 177.4 -OR10A6 ENSG00000175393 Olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene) 11 7927718-7928662 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -ZNF25 FLJ31890, KOX19, Zfp9 ENSG00000175395 Zinc finger protein 25 10 37949572-37976633 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030190 Uncertain Approved Nucleoplasm
Golgi apparatus Mixed cerebral cortex: 27.0 -OR10P1 OR10P1P, OR10P2P, OR10P3P, OST701 ENSG00000175398 Olfactory receptor, family 10, subfamily P, member 1 12 55636860-55637854 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected heart muscle: 0.2 -ARL10 ARL10A ENSG00000175414 ADP-ribosylation factor-like 10 5 176365468-176401865 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047044 Approved Mixed skin: 17.0 -CLTB Lcb ENSG00000175416 Clathrin, light chain B 5 176392455-176416569 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003692, HPA036458 Approved Supported Vesicles
Plasma membrane
Cytosol Expressed in all esophagus: 243.7 -PCSK1 NEC1, PC1, PC3, SPC3 ENSG00000175426 Proprotein convertase subtilisin/kexin type 1 5 96390415-96434143 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048564 Approved Tissue enhanced 0 cerebral cortex: 33.7 adrenal gland: 8.3 -LPL LIPD ENSG00000175445 Lipoprotein lipase 8 19901717-19967258 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048749 Approved Vesicles Tissue enhanced 0 adipose tissue: 974.6 parathyroid gland: 224.5 -RFESD ENSG00000175449 Rieske (Fe-S) domain containing 5 95646754-95684773 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016546 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 22.3 bone marrow: 16.5 -CCDC14 DKFZp434L1050, FLJ12892 ENSG00000175455 Coiled-coil domain containing 14 3 123897305-123961408 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035278, HPA035279 Uncertain Validated Centrosome Expressed in all testis: 46.4 -TBC1D10C Carabin, EPI64C, FLJ00332 ENSG00000175463 TBC1 domain family, member 10C 11 67403915-67410089 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069743 Supported Approved Nuclear bodies Tissue enhanced 0 lymph node: 46.3;spleen: 38.7 appendix: 22.9 -SART1 Ara1, SNRNP110, Snu66 ENSG00000175467 Squamous cell carcinoma antigen recognized by T cells 1 11 65961689-65979828 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031188, HPA031189, HPA031190 Supported Validated Nuclear speckles
Golgi apparatus Expressed in all spleen: 32.9 -PPP2R2D MDS026 ENSG00000175470 Protein phosphatase 2, regulatory subunit B, delta 10 131900644-131959834 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042122, HPA042770 Approved Approved Cytosol Mixed cerebral cortex: 6.7 -MCTP1 FLJ22344 ENSG00000175471 Multiple C2 domains, transmembrane 1 5 94703741-95284575 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019018 Uncertain Approved Nucleoplasm
Cytosol Mixed bone marrow: 29.1 -POLD4 p12, POLDS ENSG00000175482 Polymerase (DNA-directed), delta 4, accessory subunit 11 67350777-67356972 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071529 Uncertain Nucleus
Nucleoli
Mitochondria
Cytosol Expressed in all small intestine: 122.5 -OR52W1 OR52W1P ENSG00000175485 Olfactory receptor, family 52, subfamily W, member 1 11 6199146-6200259 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected bone marrow: 0.1 -LRRC25 FLJ38116, MAPA ENSG00000175489 Leucine rich repeat containing 25 19 18391144-18397617 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029459 Approved Tissue enhanced 0 appendix: 31.2;spleen: 41.3 bone marrow: 20.8 -DPP10 DPRP3 ENSG00000175497 Dipeptidyl-peptidase 10 (non-functional) 2 114442299-115845752 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048767 Uncertain Approved Nucleus
Vesicles
Cytosol Group enriched 7 adrenal gland: 14.2;cerebral cortex: 34.8 pancreas: 3.6 -CLCF1 BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6 ENSG00000175505 Cardiotrophin-like cytokine factor 1 11 67364168-67374177 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042444 Uncertain Approved Nuclear bodies
Vesicles Tissue enhanced 0 gallbladder: 26.4 endometrium: 21.4 -TSGA10IP FAM161C, FLJ32880 ENSG00000175513 Testis specific, 10 interacting protein 11 65945445-65959963 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 27 testis: 6.1 thyroid gland: 0.2 -GPR152 PGR5 ENSG00000175514 G protein-coupled receptor 152 11 67451301-67452729 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA035078 Uncertain Not detected parathyroid gland: 0.2 -UBQLNL MGC20470, MGC26958 ENSG00000175518 Ubiquilin-like 11 5514393-5516705 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 30 testis: 39.9 epididymis: 1.3 -UBQLN3 TUP-1 ENSG00000175520 Ubiquilin 3 11 5507300-5509985 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020547, HPA062018 Supported Tissue enriched 703 testis: 215.8 epididymis: 0.3 -PNLIP PL ENSG00000175535 Pancreatic lipase 10 116545931-116567855 Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062430, HPA062494 Supported Tissue enriched 324 pancreas: 93652.7 ovary: 288.6 -LIPT2 ENSG00000175536 Lipoyl(octanoyl) transferase 2 (putative) 11 74491712-74493733 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA040249 Approved Approved Vesicles
Centrosome Mixed testis: 14.4 -KCNE3 HOKPP, MiRP2 ENSG00000175538 Potassium channel, voltage gated subfamily E regulatory beta subunit 3 11 74454841-74467729 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014849 Approved Mixed duodenum: 72.1 -CABP4 CSNB2B ENSG00000175544 Calcium binding protein 4 11 67452406-67460313 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043702 Uncertain Tissue enhanced 0 spleen: 10.1 placenta: 2.4 -ALG10B KCR1 ENSG00000175548 ALG10B, alpha-1,2-glucosyltransferase 12 38316578-38329728 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043329, HPA063387 Approved Approved Endoplasmic reticulum Mixed parathyroid gland: 7.6 -DRAP1 NC2-alpha ENSG00000175550 DR1-associated protein 1 (negative cofactor 2 alpha) 11 65919257-65921561 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006790 Uncertain Approved Cytosol Expressed in all testis: 141.2 -LONRF3 FLJ22612, RNF127 ENSG00000175556 LON peptidase N-terminal domain and ring finger 3 X 118974614-119018355 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050422 Uncertain Approved Nucleus
Plasma membrane Mixed thyroid gland: 12.5 -UCP3 SLC25A9 ENSG00000175564 Uncoupling protein 3 (mitochondrial, proton carrier) 11 74000281-74009435 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level CAB010771, HPA072225 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enriched 19 skeletal muscle: 71.2 testis: 3.8 -UCP2 BMIQ4, SLC25A8 ENSG00000175567 Uncoupling protein 2 (mitochondrial, proton carrier) 11 73974667-73983307 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level CAB025583 Approved Expressed in all lymph node: 391.2 -C11orf68 BLES03, P5326 ENSG00000175573 Chromosome 11 open reading frame 68 11 65916808-65919117 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045938 Uncertain Approved Nucleus
Nucleoli Expressed in all cerebral cortex: 50.0 -PAAF1 FLJ11848, Rpn14, WDR71 ENSG00000175575 Proteasomal ATPase-associated factor 1 11 73876699-73931124 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039952, HPA040020 Uncertain Approved Nucleus
Cytosol Expressed in all testis: 58.0 -MRPL48 CGI-118 ENSG00000175581 Mitochondrial ribosomal protein L48 11 73787316-73865133 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040241, HPA040864 Approved Expressed in all parathyroid gland: 23.6 -RAB6A RAB6 ENSG00000175582 RAB6A, member RAS oncogene family 11 73675638-73761137 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009936, HPA059131 Approved Supported Golgi apparatus Expressed in all cerebral cortex: 269.8 -P2RY2 P2U ENSG00000175591 Purinergic receptor P2Y, G-protein coupled, 2 11 73218298-73236352 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB022642 Uncertain Uncertain Cytosol Tissue enhanced 0 esophagus: 19.0 skeletal muscle: 14.9 -FOSL1 fra-1 ENSG00000175592 FOS-like antigen 1 11 65892049-65900573 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004396, HPA066901 Uncertain Validated Nucleoplasm Tissue enhanced 0 adipose tissue: 35.2;gallbladder: 51.8 urinary bladder: 27.7 -ERCC4 FANCQ, RAD1, XPF ENSG00000175595 Excision repair cross-complementation group 4 16 13920157-13952345 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000156, HPA045828 Approved Supported Nucleoplasm
Nuclear bodies Mixed testis: 10.7 -SUGCT C7orf10, DERP13, FLJ11808, ORF19 ENSG00000175600 Succinyl-CoA:glutarate-CoA transferase 7 40134977-40860763 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026698, HPA026704, HPA026705 Supported Tissue enhanced 0 kidney: 44.6 liver: 14.6 -CCDC85B DIPA ENSG00000175602 Coiled-coil domain containing 85B 11 65890112-65891635 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054415 Uncertain Mixed cerebral cortex: 27.7 -TMEM70 FLJ20533 ENSG00000175606 Transmembrane protein 70 8 73972437-73982783 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023187, CAB034226 Uncertain Supported Nucleoplasm
Mitochondria Expressed in all skeletal muscle: 30.2 -OR4B1 OST208 ENSG00000175619 Olfactory receptor, family 4, subfamily B, member 1 11 48216792-48217762 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA059443 Uncertain Not detected epididymis: 0.0 -RPS6KB2 KLS, P70-BETA, p70S6Kb, STK14B ENSG00000175634 Ribosomal protein S6 kinase, 70kDa, polypeptide 2 11 67428460-67435408 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010010, CAB019404 Approved Supported Cytosol Expressed in all skin: 65.4 -RMI2 BLAP18, C16orf75, MGC24665 ENSG00000175643 RecQ mediated genome instability 2 16 11249619-11351762 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040995 Uncertain Supported Nuclear speckles
Cytosol Mixed lymph node: 37.3 -PRM1 CT94.1 ENSG00000175646 Protamine 1 16 11280836-11281350 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA055150 Supported Tissue enriched 5044 testis: 9152.7 small intestine: 1.8 -TOM1L2 ENSG00000175662 Target of myb1 like 2 membrane trafficking protein 17 17843511-17972422 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022541, HPA023304 Supported Supported Golgi apparatus
Intermediate filaments Expressed in all cerebral cortex: 110.9 -TEX26 C13orf26, MGC40178 ENSG00000175664 Testis expressed 26 13 30932703-30975502 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 30 testis: 40.4 cervix: 1.3 -ZNF77 pT1 ENSG00000175691 Zinc finger protein 77 19 2933218-2944971 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023397 Uncertain Approved Nucleus
Nucleoli Mixed breast: 5.7 -GPR156 GABABL, PGR28 ENSG00000175697 G protein-coupled receptor 156 3 120164645-120285094 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA028642, HPA028644 Uncertain Supported Plasma membrane Tissue enhanced 0 testis: 5.1 fallopian tube: 1.8 -LINC00116 NCRNA00116 ENSG00000175701 Long intergenic non-protein coding RNA 116 2 110211529-110245420 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all skeletal muscle: 257.7 -KDF1 C1orf172, FLJ34633, RP11-344H11.3 ENSG00000175707 Keratinocyte differentiation factor 1 1 26949562-26960406 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA028639, HPA068312 Uncertain Supported Nucleoplasm
Cell Junctions
Mitotic spindle Mixed epididymis: 23.7 -B3GNTL1 B3GNT8 ENSG00000175711 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 17 82942155-83051810 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023585, HPA024547 Supported Approved Nucleoli Mixed bone marrow: 5.0 -RBMXL3 CXorf55, FLJ40249 ENSG00000175718 RNA binding motif protein, X-linked-like 3 X 115189427-115192868 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051842 Supported Tissue enriched 26 testis: 2.5 adipose tissue: 0.0 -MLXIP bHLHe36, KIAA0867, MIR, MONDOA ENSG00000175727 MLX interacting protein 12 122078722-122147347 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023084 Approved Expressed in all rectum: 24.8 -NR2F1 COUP-TFI, EAR-3, ERBAL3, SVP44, TCFCOUP1, TFCOUP1 ENSG00000175745 Nuclear receptor subfamily 2, group F, member 1 5 93583337-93594615 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019281 Approved Nucleoplasm
Cytosol Mixed placenta: 75.3 -AURKAIP1 AIP, AKIP, FLJ20608 ENSG00000175756 Aurora kinase A interacting protein 1 1 1373730-1375495 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031821 Approved Supported Nucleoplasm
Mitochondria Expressed in all testis: 148.5 -TTLL11 bA244O19.1, C9orf20 ENSG00000175764 Tubulin tyrosine ligase-like family member 11 9 121821928-122093606 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021828 Approved Mixed testis: 21.0 -EIF4E1B FLJ36951 ENSG00000175766 Eukaryotic translation initiation factor 4E family member 1B 5 176630682-176646641 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA045045 Approved Tissue enhanced 0 cerebral cortex: 1.6;epididymis: 1.2 testis: 0.3 -TOMM5 bA613M10.3, C9orf105 ENSG00000175768 Translocase of outer mitochondrial membrane 5 homolog (yeast) 9 37582646-37592642 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048712 Approved Supported Mitochondria Expressed in all thyroid gland: 98.1 -C15orf53 FLJ35695 ENSG00000175779 Chromosome 15 open reading frame 53 15 38696598-38700038 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041914 Uncertain Not detected urinary bladder: 0.1 -SLC35E3 BLOV1 ENSG00000175782 Solute carrier family 35, member E3 12 68746106-68793964 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049403 Uncertain Mixed skin: 6.1 -PRIMA1 PRIMA ENSG00000175785 Proline rich membrane anchor 1 14 93718298-93788481 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046671, HPA060047 Approved Approved Nucleoli
Plasma membrane
Cytosol Mixed smooth muscle: 11.5 -ZNF169 MGC51961 ENSG00000175787 Zinc finger protein 169 9 94259311-94301454 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA041769 Uncertain Approved Nuclear speckles
Cytosol Mixed spleen: 7.9 -RUVBL1 ECP54, INO80H, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49a ENSG00000175792 RuvB-like AAA ATPase 1 3 128064778-128153914 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019947, HPA019948 Supported Supported Nucleoplasm
Cytosol Expressed in all fallopian tube: 80.9 -SFN YWHAS ENSG00000175793 Stratifin 1 26863138-26864457 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006268, HPA011105, CAB040552 Supported Supported Cytosol Group enriched 8 esophagus: 1094.4;skin: 1158.9 tonsil: 137.8 -MSRA ENSG00000175806 Methionine sulfoxide reductase A 8 10054268-10428891 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023804, HPA053069 Approved Validated Nucleoplasm
Cytosol Expressed in all kidney: 112.4 -ZNF645 CT138, FLJ25735, HAKAIL ENSG00000175809 Zinc finger protein 645 X 22272943-22274461 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 140 testis: 14.0 adipose tissue: 0.0 -CCDC168 C13orf40, FLJ40176 ENSG00000175820 Coiled-coil domain containing 168 13 102729369-102759070 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA048184, HPA058793 Uncertain Tissue enriched 12 testis: 7.5 epididymis: 0.6 -CTDNEP1 DULLARD, HSA011916, NET56 ENSG00000175826 CTD nuclear envelope phosphatase 1 17 7243591-7252491 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037439 Uncertain Expressed in all skeletal muscle: 190.2 -ETV4 E1A-F, E1AF, PEA3 ENSG00000175832 Ets variant 4 17 43527844-43579620 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA005768 Approved Supported Nucleoli Tissue enhanced 0 parathyroid gland: 29.7 cerebral cortex: 13.7 -SWI5 bA395P17.9, C9orf119, SAE3 ENSG00000175854 SWI5 homologous recombination repair protein 9 128275379-128288990 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052032, HPA055472 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 128.7 -GAPT C5orf29, FLJ33641 ENSG00000175857 GRB2-binding adaptor protein, transmembrane 5 58491435-58497090 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011070 Uncertain Tissue enhanced 0 appendix: 39.9;tonsil: 40.4 lymph node: 30.5 -BAIAP2 BAP2 ENSG00000175866 BAI1-associated protein 2 17 81035122-81117432 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023310, HPA027421 Approved Validated Plasma membrane
Cytosol Expressed in all cerebral cortex: 125.1 -CALCB CALC2, CGRP-II, FLJ30166 ENSG00000175868 Calcitonin-related polypeptide beta 11 14904997-15082342 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 32 thyroid gland: 32.6 parathyroid gland: 1.0 -CREG2 ENSG00000175874 Cellular repressor of E1A-stimulated genes 2 2 101345551-101387595 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038224 Supported Tissue enriched 159 cerebral cortex: 91.2 fallopian tube: 0.5 -WBSCR28 MGC26719 ENSG00000175877 Williams-Beuren syndrome chromosome region 28 7 73861159-73865893 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 97 testis: 36.2 duodenum: 0.3 -HOXD8 HOX4, HOX4E ENSG00000175879 Homeobox D8 2 176129694-176132695 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 121.2;kidney: 83.6 ovary: 43.6 -ZDHHC21 DNZ1, HSPC097 ENSG00000175893 Zinc finger, DHHC-type containing 21 9 14611071-14693471 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA065254 Approved Approved Golgi apparatus
Cytosol Mixed cerebral cortex: 16.0 -TSPEAR C21orf29, DFNB98, MGC11251, TSP-EAR ENSG00000175894 Thrombospondin-type laminin G domain and EAR repeats 21 44497892-44711580 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB034203, CAB034204, HPA052995 Approved Tissue enhanced 0 testis: 3.1 parathyroid gland: 2.6 -PLEKHF2 FLJ13187, PHAFIN2, ZFYVE18 ENSG00000175895 Pleckstrin homology domain containing, family F (with FYVE domain) member 2 8 95133804-95156684 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024829 Uncertain Expressed in all lymph node: 63.4 -A2M CPAMD5, FWP007, S863-7 ENSG00000175899 Alpha-2-macroglobulin 12 9067664-9116229 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002265, CAB017621 Supported Expressed in all lung: 1921.7 -ARL4D ARF4L ENSG00000175906 ADP-ribosylation factor-like 4D 17 43398959-43401137 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060379 Uncertain Approved Golgi apparatus
Vesicles Mixed thyroid gland: 62.4 -DOK7 C4orf25, Dok-7, FLJ33718, FLJ39137 ENSG00000175920 Docking protein 7 4 3463311-3501473 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059449 Approved Approved Nucleoplasm
Mitochondria Tissue enhanced 0 fallopian tube: 6.5;heart muscle: 9.8 skeletal muscle: 4.2 -LRRN1 FIGLER3 ENSG00000175928 Leucine rich repeat neuronal 1 3 3799437-3847703 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011071 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 44.4 parathyroid gland: 18.0 -UBE2O E2-230K ENSG00000175931 Ubiquitin-conjugating enzyme E2O 17 76389451-76453206 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023605 Uncertain Supported Nucleus
Nuclear bodies Expressed in all cerebral cortex: 36.1 -ORAI3 MGC13024, TMEM142C ENSG00000175938 ORAI calcium release-activated calcium modulator 3 16 30949066-30956461 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA015022 Uncertain Approved Nucleoplasm
Cytosol Expressed in all prostate: 26.7 -KLHL38 C8ORFK36 ENSG00000175946 Kelch-like family member 38 8 123645527-123652950 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024770, HPA027115 Uncertain Uncertain Nucleoplasm
Vesicles Group enriched 15 heart muscle: 39.2;skeletal muscle: 91.2 smooth muscle: 4.2 -UNC119B MGC5139, POC7B ENSG00000175970 Unc-119 lipid binding chaperone B 12 120710435-120723640 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all fallopian tube: 74.9 -DENND2C dJ1156J9.1, DKFZp686G0351, DKFZp779P1149, FLJ37099, RP5-1156J9.1 ENSG00000175984 DENN/MADD domain containing 2C 1 114582848-114670422 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054955 Uncertain Approved Nucleus Tissue enhanced 0 esophagus: 19.6;skeletal muscle: 14.4;skin: 14.9 testis: 9.8 -PLEKHD1 UPF0639 ENSG00000175985 Pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 14 69484692-69531551 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051875 Uncertain Tissue enhanced 0 parathyroid gland: 2.9 thyroid gland: 2.7 -ASCL3 bHLHa42, HASH3, Sgn1 ENSG00000176009 Achaete-scute family bHLH transcription factor 3 11 8937579-8938211 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027032 Uncertain Tissue enriched 9 salivary gland: 3.3 prostate: 0.3 -TUBB6 HsT1601, MGC4083 ENSG00000176014 Tubulin, beta 6 class V 18 12307669-12344320 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043640, HPA046280 Approved Approved Microtubules Expressed in all esophagus: 215.2 -LYSMD3 FLJ13542 ENSG00000176018 LysM, putative peptidoglycan-binding, domain containing 3 5 90515611-90529584 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018024 Approved Approved Cytosol Expressed in all parathyroid gland: 39.0 -AMIGO3 ENSG00000176020 Adhesion molecule with Ig-like domain 3 3 49716834-49719695 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026673 Uncertain Mixed skeletal muscle: 1.0 -B3GALT6 beta3GalT6 ENSG00000176022 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 1 1232265-1235041 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 12.1 -ZNF613 FLJ13590 ENSG00000176024 Zinc finger protein 613 19 51879872-51948759 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026833 Uncertain Approved Nucleoplasm
Vesicles Tissue enhanced 0 prostate: 25.7 parathyroid gland: 8.5 -C11orf16 ENSG00000176029 Chromosome 11 open reading frame 16 11 8920076-8933006 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 20.4;lung: 4.1 testis: 2.5 -TMPRSS7 ENSG00000176040 Transmembrane protease, serine 7 3 112034843-112081269 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040630 Uncertain Tissue enhanced 0 testis: 2.5 fallopian tube: 0.5 -NUPR1 COM1, p8 ENSG00000176046 Nuclear protein, transcriptional regulator, 1 16 28532708-28539174 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053895 Approved Nucleus
Cytosol Tissue enhanced 0 thyroid gland: 513.4 pancreas: 235.6 -JAKMIP2 JAMIP2, KIAA0555 ENSG00000176049 Janus kinase and microtubule interacting protein 2 5 147585439-147782848 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046929, HPA065023 Approved Supported Golgi apparatus Tissue enriched 6 cerebral cortex: 32.8 testis: 5.2 -MBLAC2 DKFZp686P15118, MGC46734 ENSG00000176055 Metallo-beta-lactamase domain containing 2 5 90458203-90474768 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037757, HPA060264 Uncertain Approved Nucleus
Nuclear bodies Mixed parathyroid gland: 18.4 -TPRN C9orf75, DFNB79, FLJ90254 ENSG00000176058 Taperin 9 137191617-137204193 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020899 Uncertain Approved Plasma membrane Expressed in all small intestine: 28.9 -KCNE5 KCNE1L ENSG00000176076 Potassium channel, voltage gated subfamily E regulatory beta subunit 5 X 109623700-109625172 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042316 Uncertain Uncertain Cytosol Tissue enhanced 0 cerebral cortex: 2.1 adipose tissue: 1.1 -ZNF683 Hobit, MGC33414 ENSG00000176083 Zinc finger protein 683 1 26361634-26374522 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023865 Uncertain Tissue enriched 11 testis: 78.7 lung: 7.1 -SLC35A4 ENSG00000176087 Solute carrier family 35, member A4 5 140564456-140569103 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA062210 Approved Nucleoplasm Expressed in all parathyroid gland: 110.8 -AIM1L CRYBG2, FLJ38020 ENSG00000176092 Absent in melanoma 1-like 1 26321859-26354130 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029629, HPA029631 Uncertain Approved Nucleoplasm Tissue enhanced 0 esophagus: 50.7;skin: 21.6 placenta: 9.7 -IP6K1 IHPK1, KIAA0263 ENSG00000176095 Inositol hexakisphosphate kinase 1 3 49724294-49786542 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040825 Approved Supported Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all cerebral cortex: 47.6 -SSNA1 N14, NA14 ENSG00000176101 Sjogren syndrome nuclear autoantigen 1 9 137188647-137190370 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 101.3 -CSTF3 CstF-77 ENSG00000176102 Cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 11 33077188-33162371 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039743, HPA040168 Supported Validated Nucleoplasm Expressed in all epididymis: 76.2 -YES1 c-yes, HsT441, Yes ENSG00000176105 YES proto-oncogene 1, Src family tyrosine kinase 18 721588-812546 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004370, HPA026480 Approved Supported Plasma membrane
Cytosol Expressed in all placenta: 61.6 -CHMP6 FLJ11749, VPS20 ENSG00000176108 Charged multivesicular body protein 6 17 80991598-81009517 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023001, HPA024460 Approved Expressed in all parathyroid gland: 28.1 -DLEU1 BCMS, BCMS1, DLB1, LEU1, LINC00021, NCRNA00021, XTP6 ENSG00000176124 Deleted in lymphocytic leukemia 1 (non-protein coding) 13 50082171-50723236 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB017848, HPA039465 Uncertain Approved Plasma membrane
Cytosol Mixed testis: 9.3 -UFSP1 UFSP ENSG00000176125 UFM1-specific peptidase 1 (non-functional) 7 100888723-100889718 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027099 Uncertain Mixed adipose tissue: 2.0 -MC5R ENSG00000176136 Melanocortin 5 receptor 18 13824155-13826743 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042365 Uncertain Tissue enriched 6 epididymis: 3.0 testis: 0.5 -TMEM39A FLJ10902 ENSG00000176142 Transmembrane protein 39A 3 119429500-119468830 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039140 Approved Approved Nucleoplasm
Vesicles Expressed in all cervix: 32.9 -TCP11L1 FLJ11336 ENSG00000176148 T-complex 11, testis-specific-like 1 11 33039417-33105943 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005769 Approved Approved Cytosol Mixed cerebral cortex: 20.9 -GPX2 GSHPX-GI ENSG00000176153 Glutathione peroxidase 2 14 64939152-64942905 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003545 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 gallbladder: 699.5;rectum: 466.5 stomach: 338.1 -CCDC57 FLJ00130, FLJ23754 ENSG00000176155 Coiled-coil domain containing 57 17 82101460-82212830 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023315, HPA023326, HPA023342, HPA023344 Approved Approved Microtubules
Microtubule organizing center
Cytosol Expressed in all testis: 16.1 -HSF5 FLJ40311 ENSG00000176160 Heat shock transcription factor family member 5 17 58420167-58488384 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA063613 Supported Tissue enriched 64 testis: 94.4 lymph node: 1.4 -FOXG1 BF1, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C, HBF-3, HFK1, HFK2, HFK3, QIN ENSG00000176165 Forkhead box G1 14 28765388-28770277 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 cerebral cortex: 29.7 testis: 5.3 -SPHK1 SPHK ENSG00000176170 Sphingosine kinase 1 17 76376584-76387860 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022829, HPA028761 Uncertain Supported Plasma membrane
Cytosol Mixed gallbladder: 19.0 -BNIP3 Nip3 ENSG00000176171 BCL2/adenovirus E1B 19kDa interacting protein 3 10 131966455-131982013 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003015, CAB011676 Supported Uncertain Cytosol Expressed in all cerebral cortex: 84.4 -ENTHD1 FLJ25421 ENSG00000176177 ENTH domain containing 1 22 39743044-39893864 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA019800 Uncertain Tissue enriched 24 testis: 19.6 lymph node: 0.8 -MYPOP P42pop ENSG00000176182 Myb-related transcription factor, partner of profilin 19 45890020-45902604 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA065307 Approved Nucleoplasm Mixed cerebral cortex: 10.2 -CIDEA CIDE-A ENSG00000176194 Cell death-inducing DFFA-like effector a 18 12254319-12277595 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 13 adipose tissue: 220.9 breast: 17.1 -OR11H4 ENSG00000176198 Olfactory receptor, family 11, subfamily H, member 4 14 20242739-20243820 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA052790 Uncertain Not detected epididymis: 0.0 -OR4D11 OR4D11P ENSG00000176200 Olfactory receptor, family 4, subfamily D, member 11 11 59503576-59504511 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -LRRTM4 FLJ12568 ENSG00000176204 Leucine rich repeat transmembrane neuronal 4 2 76747719-77593319 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 6 cerebral cortex: 21.4 epididymis: 3.8 -ATAD5 C17orf41, ELG1, FLJ12735, FRAG1 ENSG00000176208 ATPase family, AAA domain containing 5 17 30831970-30895869 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 7.9 lymph node: 4.4 -SMIM19 C8orf40 ENSG00000176209 Small integral membrane protein 19 8 42541155-42555193 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA011145 Uncertain Expressed in all thyroid gland: 122.6 -OR11H6 ENSG00000176219 Olfactory receptor, family 11, subfamily H, member 6 14 20223632-20224805 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -ZNF404 ENSG00000176222 Zinc finger protein 404 19 43872363-43901385 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA032014 Uncertain Approved Nucleus
Nucleoli Mixed epididymis: 12.9 -RTTN DKFZP434G145 ENSG00000176225 Rotatin 18 70003793-70205945 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041343, HPA041967 Uncertain Mixed testis: 10.1 -OR4K17 ENSG00000176230 Olfactory receptor, family 4, subfamily K, member 17 14 20117407-20118438 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -OR10H4 ENSG00000176231 Olfactory receptor, family 10, subfamily H, member 4 19 15949008-15949958 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -OR51B6 ENSG00000176239 Olfactory receptor, family 51, subfamily B, member 6 11 5351508-5352446 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -ACBD7 bA455B2.2, FLJ38219 ENSG00000176244 Acyl-CoA binding domain containing 7 10 15077523-15088776 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043326, HPA062478 Uncertain Approved Vesicles
Cytosol Tissue enriched 5 cerebral cortex: 40.8 testis: 7.9 -OR4L1 OR4L2P ENSG00000176246 Olfactory receptor, family 4, subfamily L, member 1 14 20060045-20060983 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -ANAPC2 APC2, KIAA1406 ENSG00000176248 Anaphase promoting complex subunit 2 9 137174784-137188549 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018692, HPA066539 Supported Validated Nucleoplasm Expressed in all testis: 27.1 -OR4K13 ENSG00000176253 Olfactory receptor, family 4, subfamily K, member 13 14 20033844-20034760 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -HMGB4 FLJ40388 ENSG00000176256 High mobility group box 4 1 33860475-33864791 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035699 Supported Tissue enriched 929 testis: 92.9 epididymis: 0.0 -ZBTB8OS ARCH ENSG00000176261 Zinc finger and BTB domain containing 8 opposite strand 1 32600172-32650903 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046315 Approved Approved Plasma membrane Expressed in all lymph node: 42.9 -OR4F21 OR4F21P ENSG00000176269 Olfactory receptor, family 4, subfamily F, member 21 8 166049-167043 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA047705 Uncertain Not detected testis: 0.2 -SLC35G1 C10orf60, FLJ33990, TMEM20 ENSG00000176273 Solute carrier family 35, member G1 10 93893973-93956062 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 8 duodenum: 88.4;small intestine: 45.8 rectum: 7.9 -OR4K5 ENSG00000176281 Olfactory receptor, family 4, subfamily K, member 5 14 19920582-19921659 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -ZNF135 pHZ-17, ZNF61, ZNF78L1 ENSG00000176293 Zinc finger protein 135 19 58059239-58086310 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA006961 Approved Approved Cytosol Mixed parathyroid gland: 24.5 -OR4N2 ENSG00000176294 Olfactory receptor, family 4, subfamily N, member 2 14 19719015-19828372 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 15 testis: 26.7 cerebral cortex: 1.7 -OR4M1 ENSG00000176299 Olfactory receptor, family 4, subfamily M, member 1 14 19780242-19781357 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058889 Uncertain Tissue enriched 10 testis: 1.0 adipose tissue: 0.0 -FOXR1 DLNB13, FOXN5 ENSG00000176302 Forkhead box R1 11 118971707-118981291 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 14 testis: 3.1 thyroid gland: 0.2 -COX8A COX, COX8, COX8-2, COX8L, VIII, VIII-L ENSG00000176340 Cytochrome c oxidase subunit VIIIA (ubiquitous) 11 63974607-63976543 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055942 Supported Expressed in all skeletal muscle: 512.5 -TAC4 HK-1, PPT-C, Pptc ENSG00000176358 Tachykinin 4 (hemokinin) 17 49838309-49848017 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed skin: 2.0 -ZSCAN2 FLJ20595, ZFP29, ZNF854 ENSG00000176371 Zinc finger and SCAN domain containing 2 15 84600986-84627796 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA007296, HPA024331 Supported Approved Nucleoplasm
Cytosol Expressed in all testis: 14.0 -PRR18 MGC35308 ENSG00000176381 Proline rich 18 6 166305300-166308448 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 10 cerebral cortex: 32.7 fallopian tube: 3.4 -B3GNT4 B3GN-T4, beta3Gn-T4 ENSG00000176383 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 12 122203543-122208952 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055261 Uncertain Approved Nucleoli
Mitochondria Tissue enhanced 0 cerebral cortex: 4.3;skin: 2.9 kidney: 1.9 -CDC26 ANAPC12, APC12, C9orf17 ENSG00000176386 Cell division cycle 26 9 113255835-113275589 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044130 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 62.7 -HSD11B2 SDR9C3 ENSG00000176387 Hydroxysteroid (11-beta) dehydrogenase 2 16 67430652-67437553 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032443, HPA042186, HPA056385 Supported Approved Vesicles Tissue enhanced 0 colon: 154.2;kidney: 172.7 salivary gland: 123.5 -CRLF3 CREME9, CYTOR4 ENSG00000176390 Cytokine receptor-like factor 3 17 30769388-30824776 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007596 Supported Supported Plasma membrane
Cytosol Mixed lymph node: 39.9 -RNPEP ENSG00000176393 Arginyl aminopeptidase (aminopeptidase B) 1 201982372-202006147 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036074, HPA036075, HPA061487 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all duodenum: 68.3 -EID2 CRI2, EID-2, MGC20452 ENSG00000176396 EP300 interacting inhibitor of differentiation 2 19 39538250-39540230 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045477 Uncertain Supported Nucleoplasm Expressed in all cerebral cortex: 21.4 -DMRTA1 ENSG00000176399 DMRT-like family A1 9 22446841-22455740 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044764, HPA062253 Uncertain Approved Vesicles Tissue enhanced 0 parathyroid gland: 6.4 liver: 4.3 -EID2B EID-3, FLJ38944 ENSG00000176401 EP300 interacting inhibitor of differentiation 2B 19 39530990-39532854 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA064185 Approved Mixed cerebral cortex: 12.5 -GJC3 CX30.2, GJE1 ENSG00000176402 Gap junction protein, gamma 3, 30.2kDa 7 99923269-99929620 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015024 Uncertain Tissue enhanced 0 breast: 8.9;prostate: 5.6 testis: 3.2 -RIMS2 KIAA0751, OBOE, RAB3IP3, RIM2 ENSG00000176406 Regulating synaptic membrane exocytosis 2 8 103500748-104256094 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046538, HPA066498 Supported Approved Cytosol Tissue enhanced 0 adrenal gland: 68.1;cerebral cortex: 45.4 cervix: 11.5 -KCMF1 DEBT91, DKFZP434L1021, PCMF, ZZZ1 ENSG00000176407 Potassium channel modulatory factor 1 2 84971093-85059472 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030383, HPA030384 Approved Validated Nucleoplasm
Cytosol Expressed in all testis: 123.9 -DNAJC30 WBSCR18 ENSG00000176410 DnaJ (Hsp40) homolog, subfamily C, member 30 7 73680969-73683453 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017318 Uncertain Supported Expressed in all testis: 11.3 -SPRYD4 DKFZp686N0877 ENSG00000176422 SPRY domain containing 4 12 56468567-56479707 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053469 Approved Approved Nucleoplasm Expressed in all liver: 35.4 -VPS37D MGC35352, WBSCR24 ENSG00000176428 Vacuolar protein sorting 37 homolog D (S. cerevisiae) 7 73667825-73672112 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040978 Uncertain Approved Vesicles Mixed cerebral cortex: 6.4 -CLEC14A C14orf27 ENSG00000176435 C-type lectin domain family 14, member A 14 38254103-38256369 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039468, HPA048119 Uncertain Supported Endoplasmic reticulum
Golgi apparatus Tissue enhanced 0 lung: 76.4 adipose tissue: 40.9 -SYNE3 C14orf49, FLJ25605, Nesp3, Nesprin-3, NET53 ENSG00000176438 Spectrin repeat containing, nuclear envelope family member 3 14 95407266-95475836 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055227, HPA077140 Approved Supported Nuclear membrane Mixed adipose tissue: 14.6 -CLK2 clk2 ENSG00000176444 CDC-like kinase 2 1 155262868-155278491 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055366, HPA059507 Approved Validated Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 26.3 -LPCAT4 AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2 ENSG00000176454 Lysophosphatidylcholine acyltransferase 4 15 34358618-34367278 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030719 Uncertain Mixed rectum: 39.2 -SLCO3A1 OATP-D, OATP3A1, SLC21A11 ENSG00000176463 Solute carrier organic anion transporter family, member 3A1 15 91853695-92172435 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed parathyroid gland: 26.5 -ZNF575 FLJ32567 ENSG00000176472 Zinc finger protein 575 19 43525497-43536130 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051865 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Mixed colon: 4.5 -WDR25 C14orf67, MGC4645 ENSG00000176473 WD repeat domain 25 14 100376418-100530303 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003113 Approved Supported Nucleoplasm Expressed in all thyroid gland: 13.5 -SGF29 CCDC101, FLJ32446, TDRD29 ENSG00000176476 SAGA complex associated factor 29 16 28553915-28591790 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052590, HPA053608 Supported Approved Nucleus
Nucleoli Expressed in all testis: 41.7 -PLA2G16 AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754. ENSG00000176485 Phospholipase A2, group XVI 11 63573195-63616883 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058997 Uncertain Approved Mitochondria Expressed in all adipose tissue: 327.0 -DIRAS1 Di-Ras1, GBTS1, RIG ENSG00000176490 DIRAS family, GTP-binding RAS-like 1 19 2714567-2721418 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 71.1;heart muscle: 48.4 parathyroid gland: 23.6 -OR5AN1 ENSG00000176495 Olfactory receptor, family 5, subfamily AN, member 1 11 59364412-59365448 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -PHLDB3 FLJ40193 ENSG00000176531 Pleckstrin homology-like domain, family B, member 3 19 43474954-43504935 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043425 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Expressed in all testis: 24.8 -PRR15 ENSG00000176532 Proline rich 15 7 29563811-29567295 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040996, HPA048121 Supported Uncertain Vesicles
Cell Junctions Tissue enhanced 0 cervix, uterine: 91.8 small intestine: 80.6 -GNG7 FLJ00058 ENSG00000176533 Guanine nucleotide binding protein (G protein), gamma 7 19 2511219-2702709 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057790 Approved Expressed in all cerebral cortex: 49.9 -OR4C5 OR4C5P, OR4C5Q ENSG00000176540 Olfactory receptor, family 4, subfamily C, member 5 (gene/pseudogene) 11 48365485-48366465 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA049516 Uncertain Not detected epididymis: 0.0 -USF3 KIAA2018 ENSG00000176542 Upstream transcription factor family member 3 3 113648385-113696646 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029243, HPA029245 Uncertain Uncertain Nucleoplasm
Nucleoli
Centrosome Mixed parathyroid gland: 13.4 -OR4C3 ENSG00000176547 Olfactory receptor, family 4, subfamily C, member 3 11 48324920-48328471 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA049116 Uncertain Not detected epididymis: 0.0 -OR4S1 ENSG00000176555 Olfactory receptor, family 4, subfamily S, member 1 11 48306223-48307152 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -CNTD1 CNTD, FLJ40137 ENSG00000176563 Cyclin N-terminal domain containing 1 17 42798792-42811587 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023324 Uncertain Nucleoplasm
Plasma membrane
Focal adhesion sites Tissue enriched 32 testis: 72.3 stomach: 2.2 -DCAF4L2 WDR21C ENSG00000176566 DDB1 and CUL4 associated factor 4-like 2 8 87870743-87874068 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067584 Uncertain Tissue enriched 388 testis: 38.8 adipose tissue: 0.0 -OR4X1 ENSG00000176567 Olfactory receptor, family 4, subfamily X, member 1 (gene/pseudogene) 11 48263861-48264778 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -CNBD1 FLJ35802 ENSG00000176571 Cyclic nucleotide binding domain containing 1 8 86866442-87615219 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA025037, HPA027469, HPA027786 Uncertain Tissue enriched 12 testis: 11.6 spleen: 0.9 -KBTBD11 KIAA0711, KLHDC7C ENSG00000176595 Kelch repeat and BTB (POZ) domain containing 11 8 1973878-2006936 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051159 Uncertain Approved Intermediate filaments Tissue enhanced 0 cerebral cortex: 21.8 small intestine: 8.9 -B3GNT5 B3GN-T5, beta3Gn-T5 ENSG00000176597 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 3 183253244-183298504 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017292 Uncertain Approved Nucleoli Expressed in all bone marrow: 49.2 -MAP3K19 FLJ23074, RCK, YSK4 ENSG00000176601 Mitogen-activated protein kinase kinase kinase 19 2 134964491-135047468 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA011388 Uncertain Cytosol Group enriched 9 fallopian tube: 32.7;testis: 18.0 lung: 2.9 -C14orf177 FLJ25773 ENSG00000176605 Chromosome 14 open reading frame 177 14 98711613-98717761 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018091 Uncertain Tissue enriched 23 testis: 2.2 adipose tissue: 0.0 -LMNB2 LMN2 ENSG00000176619 Lamin B2 19 2427638-2456996 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB022593, HPA047863, HPA062477 Supported Supported Nuclear membrane Expressed in all appendix: 21.2 -RMDN1 CGI-90, FAM82B, FLJ20665, RMD1 ENSG00000176623 Regulator of microtubule dynamics 1 8 86468257-86514357 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026495 Approved Supported Centrosome Expressed in all thyroid gland: 83.9 -MEX3C FLJ38871, RKHD2, RNF194 ENSG00000176624 Mex-3 RNA binding family member C 18 51174550-51218304 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040603 Uncertain Approved Vesicles Expressed in all testis: 81.3 -HORMAD2 CT46.2, MGC26710 ENSG00000176635 HORMA domain containing 2 22 30080174-30177075 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003074 Supported Tissue enriched 21 testis: 35.0 liver: 1.6 -RNF152 FLJ39176 ENSG00000176641 Ring finger protein 152 18 61808063-61894247 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 5 kidney: 56.2 liver: 10.3 -MYO1D KIAA0727, myr4, PPP1R108 ENSG00000176658 Myosin ID 17 32492522-32877177 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054744 Uncertain Approved Cytosol Mixed colon: 110.9 -FOXL1 FKH6, FKHL11, FREAC7 ENSG00000176678 Forkhead box L1 16 86576368-86582160 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 gallbladder: 8.4 duodenum: 3.2 -TGIF2LY ENSG00000176679 TGFB-induced factor homeobox 2-like, Y-linked Y 3579041-3580041 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 74 testis: 7.3 epididymis: 0.0 -LRRC37A KIAA0563 ENSG00000176681 Leucine rich repeat containing 37A 17 46292733-46337794 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042121, HPA042701, HPA043056, HPA045090, HPA049080 Supported Approved Vesicles Tissue enriched 8 testis: 13.5 skeletal muscle: 1.6 -FOXC2 FKHL14, MFH-1 ENSG00000176692 Forkhead box C2 16 86567251-86569728 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056302 Supported Nucleoplasm
Nuclear bodies Mixed kidney: 2.8 -OR4F17 OR4F11P, OR4F18, OR4F19 ENSG00000176695 Olfactory receptor, family 4, subfamily F, member 17 19 107461-111696 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -BDNF ENSG00000176697 Brain-derived neurotrophic factor 11 27654893-27722058 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009564, HPA031440, HPA056104 Supported Supported Nuclear speckles
Mitochondria Tissue enhanced 0 cerebral cortex: 12.0 epididymis: 5.8 -CCDC121 FLJ13646, FLJ43364 ENSG00000176714 Coiled-coil domain containing 121 2 27625639-27629012 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051791 Uncertain Approved Actin filaments
Cytosol Tissue enhanced 0 testis: 46.6 ovary: 12.2 -ACSF3 ENSG00000176715 Acyl-CoA synthetase family member 3 16 89088375-89155846 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all duodenum: 31.9 -BOK BCL2L9, BOKL, MGC4631 ENSG00000176720 BCL2-related ovarian killer 2 241558721-241574138 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adipose tissue: 97.3 endometrium: 35.9 -ZNF843 MGC46336 ENSG00000176723 Zinc finger protein 843 16 31432593-31443160 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA030911, HPA030912 Uncertain Mixed ovary: 3.8 -C8orf59 ENSG00000176731 Chromosome 8 open reading frame 59 8 85214076-85220421 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044805, HPA071903 Approved Nucleus
Nucleoli
Cytosol Expressed in all breast: 119.7 -PFN4 ENSG00000176732 Profilin family, member 4 2 24115371-24123477 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 39 testis: 139.0 thyroid gland: 3.5 -OR51V1 OR51A12 ENSG00000176742 Olfactory receptor, family 51, subfamily V, member 1 11 5199735-5200700 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -MAGEB6 CT3.4, FLJ40242, MAGE-B6, MAGEB6A ENSG00000176746 Melanoma antigen family B6 X 26192440-26195646 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041853 Approved Tissue enriched 58 testis: 5.7 epididymis: 0.0 -CDK5R1 Nck5a, p35nck5a ENSG00000176749 Cyclin-dependent kinase 5, regulatory subunit 1 (p35) 17 32486619-32491256 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000252 Supported Nucleoplasm
Vesicles Tissue enriched 7 cerebral cortex: 98.7 lymph node: 14.9 -TCERG1L FLJ38950 ENSG00000176769 Transcription elongation regulator 1-like 10 131092391-131311721 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 thyroid gland: 25.1 cerebral cortex: 4.1 -NCKAP5 ERIH1, ERIH2, NAP5 ENSG00000176771 NCK-associated protein 5 2 132671799-133568463 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034639, HPA044859 Uncertain Approved Nucleoli
Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 lung: 14.2 cerebral cortex: 4.1 -MAGEB18 MGC33889 ENSG00000176774 Melanoma antigen family B18 X 26138343-26140735 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046141, HPA050600 Uncertain Tissue enriched 14 testis: 1.3 epididymis: 0.0 -DEFB104A DEFB-4, DEFB104, DEFB4 ENSG00000176782 Defensin, beta 104A 8 7836471-7841242 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA045292 Supported Tissue enriched 598 epididymis: 572.3 esophagus: 0.9 -RUFY1 FLJ22251, RABIP4, ZFYVE12 ENSG00000176783 RUN and FYVE domain containing 1 5 179550558-179610026 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038804, HPA057614 Approved Supported Nucleus
Vesicles
Cytosol Expressed in all spleen: 41.4 -OR52E2 ENSG00000176787 Olfactory receptor, family 52, subfamily E, member 2 11 5058650-5059627 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA045748 Uncertain Not detected testis: 0.4 -BASP1 CAP-23, CAP23, NAP-22, NAP22 ENSG00000176788 Brain abundant, membrane attached signal protein 1 5 17065598-17276843 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045218, HPA050333 Supported Validated Plasma membrane Tissue enhanced 0 cerebral cortex: 420.3;epididymis: 364.8 prostate: 133.3 -DEFB103A DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3 ENSG00000176797 Defensin, beta 103A 8 7881204-7882664 Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 tonsil: 2.2 skin: 0.8 -OR51L1 ENSG00000176798 Olfactory receptor, family 51, subfamily L, member 1 11 4998983-4999930 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -LRRC37A3 FLJ34306, KIAA0563 ENSG00000176809 Leucine rich repeat containing 37, member A3 17 64854312-64919480 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042121, HPA042701, HPA043056, HPA045090 Supported Approved Vesicles Tissue enhanced 0 testis: 31.5 epididymis: 14.5 -VSIG10 ENSG00000176834 V-set and immunoglobulin domain containing 10 12 118063593-118136026 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014526 Approved Cytosol Mixed small intestine: 28.3 -IRX5 IRX-2a ENSG00000176842 Iroquois homeobox 5 16 54930862-54934485 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047130 Approved Nuclear speckles
Microtubules
Cytosol Tissue enhanced 0 breast: 18.6;lung: 10.8;skin: 11.1 salivary gland: 5.5 -METRNL ENSG00000176845 Meteorin, glial cell differentiation regulator-like 17 83079691-83095119 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023792 Uncertain Mixed skin: 31.0 -FAM91A1 FLJ23790 ENSG00000176853 Family with sequence similarity 91, member A1 8 123768456-123815452 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027978 Approved Approved Nucleoplasm
Microtubules Expressed in all parathyroid gland: 36.1 -WSB2 MGC10210, SBA2 ENSG00000176871 WD repeat and SOCS box containing 2 12 118032694-118062430 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052606 Uncertain Expressed in all cerebral cortex: 193.8 -OR51G1 OR51G3P ENSG00000176879 Olfactory receptor, family 51, subfamily G, member 1 (gene/pseudogene) 11 4923374-4924339 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA050482 Uncertain Not detected adipose tissue: 0.0 -GRIN1 GluN1, NMDAR1 ENSG00000176884 Glutamate receptor, ionotropic, N-methyl D-aspartate 1 9 137138390-137168762 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB006831 Approved Tissue enriched 202 cerebral cortex: 152.3 prostate: 0.7 -SOX11 ENSG00000176887 SRY (sex determining region Y)-box 11 2 5692667-5701385 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000536, CAB056152, CAB056153 Approved Tissue enriched 14 cerebral cortex: 5.4 smooth muscle: 0.3 -TYMS HsT422, TMS, TS, Tsase ENSG00000176890 Thymidylate synthetase 18 657604-673578 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002784 Approved Mixed testis: 58.9 -OR51G2 ENSG00000176893 Olfactory receptor, family 51, subfamily G, member 2 11 4914719-4915663 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -PXMP2 PMP22 ENSG00000176894 Peroxisomal membrane protein 2, 22kDa 12 132687606-132704991 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all liver: 119.8 -OR51A7 ENSG00000176895 Olfactory receptor, family 51, subfamily A, member 7 11 4907370-4908308 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA061356 Uncertain Not detected testis: 0.2 -TCEANC MGC17403 ENSG00000176896 Transcription elongation factor A (SII) N-terminal and central domain containing X 13653189-13681964 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001013 Uncertain Mixed spleen: 3.5 -OR51T1 ENSG00000176900 Olfactory receptor, family 51, subfamily T, member 1 11 4881819-4882883 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA046877 Uncertain Not detected prostate: 0.1 -PNMA1 MA1 ENSG00000176903 Paraneoplastic Ma antigen 1 14 73711783-73714372 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003817, HPA015007 Supported Supported Focal adhesion sites
Cytosol Expressed in all cerebral cortex: 194.0 -OR51H1 OR51H1P ENSG00000176904 Olfactory receptor, family 51, subfamily H, member 1 11 4859656-4860564 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.5 -C8orf4 hTC-1, TC-1 ENSG00000176907 Chromosome 8 open reading frame 4 8 40153455-40155308 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027188 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Mixed placenta: 231.6 -MAMSTR FLJ36070, MASTR ENSG00000176909 MEF2 activating motif and SAP domain containing transcriptional regulator 19 48712742-48719721 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049765 Approved Nuclear speckles Tissue enhanced 0 adrenal gland: 21.5;skeletal muscle: 31.4 fallopian tube: 10.4 -ANKLE2 KIAA0692, Lem4, LEMD7 ENSG00000176915 Ankyrin repeat and LEM domain containing 2 12 132725503-132761888 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003602, HPA074838 Uncertain Supported Endoplasmic reticulum
Plasma membrane Expressed in all testis: 80.1 -C8G ENSG00000176919 Complement component 8, gamma polypeptide 9 136945246-136946974 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046269 Approved Uncertain Endoplasmic reticulum Group enriched 6 duodenum: 51.3;liver: 106.1;small intestine: 35.3 gallbladder: 9.9 -FUT2 SE, Se2, SEC2, sej ENSG00000176920 Fucosyltransferase 2 (secretor status included) 19 48695971-48705950 Blood group antigen proteins, Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014402 Uncertain Uncertain Plasma membrane
Cytosol Tissue enhanced 0 duodenum: 52.9 stomach: 32.5 -OR51S1 ENSG00000176922 Olfactory receptor, family 51, subfamily S, member 1 11 4848237-4849208 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.1 -OR51F2 ENSG00000176925 Olfactory receptor, family 51, subfamily F, member 2 11 4821386-4822414 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -EFCAB5 FLJ46247 ENSG00000176927 EF-hand calcium binding domain 5 17 29929200-30108452 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022852, HPA028608 Uncertain Tissue enriched 10 testis: 15.3 rectum: 1.5 -GCNT4 C2GNT3 ENSG00000176928 Glucosaminyl (N-acetyl) transferase 4, core 2 5 75025346-75030899 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA037431 Approved Supported Nucleoplasm
Golgi apparatus Tissue enhanced 0 duodenum: 22.0 parathyroid gland: 20.7 -OR52R1 ENSG00000176937 Olfactory receptor, family 52, subfamily R, member 1 (gene/pseudogene) 11 4803433-4804380 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -MUC20 FLJ14408, KIAA1359 ENSG00000176945 Mucin 20, cell surface associated 3 195720882-195741123 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042249 Approved Nucleoplasm
Plasma membrane
Cytosol Mixed colon: 10.9 -THAP4 CGI-36 ENSG00000176946 THAP domain containing 4 2 241584405-241637449 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044982, HPA053448 Uncertain Approved Nucleoplasm
Nuclear speckles Expressed in all parathyroid gland: 81.6 -NFATC2IP ESC2, FLJ14639, NIP45, RAD60 ENSG00000176953 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 16 28950807-28967097 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053587 Approved Nucleus Expressed in all lymph node: 43.2 -LY6H NMLY6 ENSG00000176956 Lymphocyte antigen 6 complex, locus H 8 143157914-143160711 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 14 cerebral cortex: 38.1 duodenum: 2.6 -FIBIN MGC24932 ENSG00000176971 Fin bud initiation factor homolog (zebrafish) 11 26994184-26996121 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040120 Uncertain Tissue enhanced 0 seminal vesicle: 123.3 lung: 37.6 -FAM89B ENSG00000176973 Family with sequence similarity 89, member B 11 65572349-65574198 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046895 Approved Expressed in all skeletal muscle: 38.5 -SHMT1 CSHMT, MGC15229, MGC24556, SHMT ENSG00000176974 Serine hydroxymethyltransferase 1 (soluble) 17 18327860-18363563 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023314 Approved Supported Nucleus
Cytosol Expressed in all kidney: 270.2 -DPP7 DPPII ENSG00000176978 Dipeptidyl-peptidase 7 9 137110542-137115177 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021282, CAB025541, HPA059381 Supported Validated Golgi apparatus
Vesicles Expressed in all adrenal gland: 71.0 -TRIM60 FLJ35882, RNF129, RNF33 ENSG00000176979 Tripartite motif containing 60 4 165031953-165041744 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035809, HPA035810, HPA061496 Uncertain Group enriched 13 placenta: 2.1;testis: 2.7 skin: 0.1 -SEC24C KIAA0079 ENSG00000176986 SEC24 homolog C, COPII coat complex component 10 73744384-73772161 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040196, HPA040213 Supported Supported Vesicles Expressed in all parathyroid gland: 82.7 -FMR1NB CT37, FLJ25736, NY-SAR-35 ENSG00000176988 Fragile X mental retardation 1 neighbor X 147981329-148026667 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011284, CAB026403 Supported Tissue enriched 420 testis: 86.4 epididymis: 0.2 -SMCR8 FLJ34716 ENSG00000176994 Smith-Magenis syndrome chromosome region, candidate 8 17 18315310-18328055 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021557, HPA024646 Uncertain Validated Nucleoplasm Expressed in all parathyroid gland: 17.8 -MTHFR ENSG00000177000 Methylenetetrahydrofolate reductase (NAD(P)H) 1 11785723-11806920 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063389 Approved Cell Junctions Expressed in all epididymis: 65.3 -DEFB104B ENSG00000177023 Defensin, beta 104B 8 7470308-7475082 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA045292 Supported Tissue enriched 598 epididymis: 572.3 esophagus: 0.9 -C19orf18 MGC41906 ENSG00000177025 Chromosome 19 open reading frame 18 19 57958437-57974534 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014527 Uncertain Approved Golgi apparatus Tissue enhanced 0 testis: 16.9 epididymis: 4.8 -DEAF1 NUDR, SPN, ZMYND5 ENSG00000177030 DEAF1 transcription factor 11 644233-706715 Disease related genes, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030302 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all cerebral cortex: 40.8 -MTX3 ENSG00000177034 Metaxin 3 5 79976731-79991262 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047858, HPA062061 Approved Approved Mitochondria Expressed in all parathyroid gland: 34.2 -TMEM80 FLJ38216 ENSG00000177042 Transmembrane protein 80 11 695428-705028 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059592, HPA067046 Uncertain Approved Golgi apparatus Expressed in all thyroid gland: 43.4 -SIX5 DMAHP ENSG00000177045 SIX homeobox 5 19 45764785-45769226 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042068 Approved Mixed ovary: 33.6 -IFNW1 ENSG00000177047 Interferon, omega 1 9 21140214-21142145 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Not detected smooth muscle: 0.1 -FBXO46 20D7-FC4, Fbx46, FBXO34L ENSG00000177051 F-box protein 46 19 45710629-45730904 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049390 Uncertain Approved Nucleus
Vesicles
Cytosol Expressed in all lymph node: 17.9 -ZDHHC13 FLJ10852, FLJ10941, HIP14L ENSG00000177054 Zinc finger, DHHC-type containing 13 11 19117099-19176422 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016759, HPA018791 Uncertain Validated Vesicles Mixed esophagus: 40.5 -SLC38A9 FLJ90709 ENSG00000177058 Solute carrier family 38, member 9 5 55625845-55773194 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043785 Uncertain Approved Nucleoplasm
Vesicles Expressed in all placenta: 79.8 -ACER2 ASAH3L, FLJ41587 ENSG00000177076 Alkaline ceramidase 2 9 19409059-19452020 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 5 placenta: 14.7;stomach: 63.7;urinary bladder: 45.8 skin: 7.6 -WDR73 FLJ14888, HSPC264 ENSG00000177082 WD repeat domain 73 15 84639281-84654343 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039357 Uncertain Mixed thyroid gland: 5.1 -POLE POLE1 ENSG00000177084 Polymerase (DNA directed), epsilon, catalytic subunit 12 132623753-132687365 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058210, HPA067385 Validated Nucleus
Plasma membrane Expressed in all testis: 22.0 -FAM109B DKFZp686J07229 ENSG00000177096 Family with sequence similarity 109, member B 22 42074251-42079441 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000647 Uncertain Mixed placenta: 22.4 -SCN4B LQT10 ENSG00000177098 Sodium channel, voltage gated, type IV beta subunit 11 118133377-118152888 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017293 Approved Tissue enhanced 0 adipose tissue: 25.0 thyroid gland: 17.0 -DSCAML1 KIAA1132 ENSG00000177103 Down syndrome cell adhesion molecule like 1 11 117427773-117817525 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035230 Uncertain Tissue enhanced 0 cerebral cortex: 12.1 ovary: 4.4 -RHOG ARHG, MGC125835, MGC125836, RhoG ENSG00000177105 Ras homolog family member G 11 3826978-3840983 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039871 Supported Expressed in all bone marrow: 170.8 -EPS8L2 FLJ21935, FLJ22171, MGC3088 ENSG00000177106 EPS8-like 2 11 694438-727727 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041143 Approved Supported Plasma membrane
Cytosol Mixed small intestine: 112.7 -ZDHHC22 C14orf59 ENSG00000177108 Zinc finger, DHHC-type containing 22 14 77131270-77142734 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA072213 Approved Plasma membrane Tissue enriched 57 cerebral cortex: 64.4 epididymis: 1.1 -ANO6 DKFZp313M0720, TMEM16F ENSG00000177119 Anoctamin 6 12 45215987-45440404 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038958 Approved Approved Plasma membrane
Cytosol Expressed in all adipose tissue: 90.8 -ZBTB34 KIAA1993, MGC24652, ZNF918 ENSG00000177125 Zinc finger and BTB domain containing 34 9 126860665-126885878 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA023893 Approved Supported Nucleoplasm Mixed placenta: 9.5 -FAM9B TEX39B ENSG00000177138 Family with sequence similarity 9, member B X 9024232-9164639 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035135 Uncertain Uncertain Nucleoplasm Tissue enriched 24 testis: 10.3 prostate: 0.4 -CETN1 CEN1, CETN ENSG00000177143 Centrin, EF-hand protein, 1 18 580357-582114 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028956, CAB037244 Approved Tissue enriched 1421 testis: 142.0 adipose tissue: 0.0 -FAM210A C18orf19, HsT2329, MGC24180 ENSG00000177150 Family with sequence similarity 210, member A 18 13663347-13726663 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014324, HPA051564 Uncertain Approved Nucleus
Golgi apparatus
Mitochondria Mixed testis: 15.7 -OR2T35 ENSG00000177151 Olfactory receptor, family 2, subfamily T, member 35 1 248638287-248639258 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -TALDO1 ENSG00000177156 Transaldolase 1 11 747329-765024 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040373, HPA048089 Validated Nucleoplasm
Cytosol Expressed in all esophagus: 263.9 -ULK1 ATG1, ATG1A ENSG00000177169 Unc-51 like autophagy activating kinase 1 12 131894651-131923167 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063990 Approved Cytosol Expressed in all skin: 23.7 -OR14C36 OR5BF1 ENSG00000177174 Olfactory receptor, family 14, subfamily C, member 36 1 248348775-248349713 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected prostate: 0.1 -RIMKLA FAM80A, MGC47816, NAAGS-II, RP11-157D18.1 ENSG00000177181 Ribosomal modification protein rimK-like family member A 1 42380795-42422578 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027826 Uncertain Uncertain Nucleoli fibrillar center Tissue enhanced 0 cerebral cortex: 10.3 rectum: 3.9 -CLVS1 C6orf212L, CRALBPL, MGC34646, RLBP1L1 ENSG00000177182 Clavesin 1 8 61057158-61501645 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 10.2;testis: 6.3 thyroid gland: 2.0 -OR2M7 ENSG00000177186 Olfactory receptor, family 2, subfamily M, member 7 1 248323630-248324568 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -RPS6KA3 CLS, HU-3, MRX19, RSK, RSK2 ENSG00000177189 Ribosomal protein S6 kinase, 90kDa, polypeptide 3 X 20149911-20267100 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003221, CAB003853, CAB013520 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all parathyroid gland: 91.0 -B3GNT8 B3GALT7, beta3Gn-T8, BGALT15 ENSG00000177191 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 19 41425359-41428730 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043669 Supported Tissue enhanced 0 duodenum: 16.0;small intestine: 17.2 esophagus: 10.7 -PUS1 ENSG00000177192 Pseudouridylate synthase 1 12 131929200-131945896 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051636, HPA057593 Approved Supported Nucleus
Mitochondria Expressed in all lymph node: 21.6 -CHD9 BC022889, FLJ12178, KIAA0308 ENSG00000177200 Chromodomain helicase DNA binding protein 9 16 53055033-53329150 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042053, HPA049420 Approved Approved Plasma membrane
Cytosol Expressed in all parathyroid gland: 26.8 -OR2T12 ENSG00000177201 Olfactory receptor, family 2, subfamily T, member 12 1 248294616-248295578 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -SPACA4 SAMP14 ENSG00000177202 Sperm acrosome associated 4 19 48606743-48607714 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041927, HPA061302 Supported Tissue enriched 15 testis: 65.0 stomach: 4.2 -OR2T33 ENSG00000177212 Olfactory receptor, family 2, subfamily T, member 33 1 248272852-248273814 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected bone marrow: 0.2 -PDDC1 FLJ34283 ENSG00000177225 Parkinson disease 7 domain containing 1 11 767220-777488 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008812 Uncertain Supported Nucleoplasm Expressed in all cerebral cortex: 31.8 -TRIM72 MG53 ENSG00000177238 Tripartite motif containing 72, E3 ubiquitin protein ligase 16 31214021-31231537 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023122, HPA054909 Supported Approved Nucleus
Nucleoli Tissue enriched 21 skeletal muscle: 52.5 prostate: 2.4 -MAN1B1 MANA-ER, MRT15 ENSG00000177239 Mannosidase, alpha, class 1B, member 1 9 137086927-137109187 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051516 Approved Uncertain Vesicles Expressed in all fallopian tube: 33.0 -DEFB103B ENSG00000177243 Defensin, beta 103B 8 7428888-7430348 Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 tonsil: 2.2 skin: 0.8 -DEFB4B DEFB4P ENSG00000177257 Defensin, beta 4B 8 7414860-7416863 Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 20 tonsil: 2.8 skin: 0.1 -KCNA3 HLK3, HPCN3, Kv1.3, MK3 ENSG00000177272 Potassium channel, voltage gated shaker related subfamily A, member 3 1 110672465-110675033 FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016625 Approved Mixed lymph node: 10.7 -OR2AJ1 OR2AJ1P, OR2AJ1Q ENSG00000177275 Olfactory receptor, family 2, subfamily AJ, member 1 1 247933769-247934755 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected spleen: 0.1 -FZD8 ENSG00000177283 Frizzled class receptor 8 10 35638249-35642278 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045025, HPA071142 Approved Approved Endoplasmic reticulum Tissue enhanced 0 spleen: 16.2 lung: 6.6 -GJD4 CX40.1, FLJ90023 ENSG00000177291 Gap junction protein, delta 4, 40.1kDa 10 35605410-35608935 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA038266 Approved Mixed cerebral cortex: 1.7 -FBXO39 CT144, Fbx39, MGC35179 ENSG00000177294 F-box protein 39 17 6776223-6797101 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 62 testis: 53.2 ovary: 0.8 -CLDN22 CLDN21 ENSG00000177300 Claudin 22 4 183318194-183320774 Predicted membrane proteins, Transporters Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.1 -KCNA2 HK4, Kv1.2 ENSG00000177301 Potassium channel, voltage gated shaker related subfamily A, member 2 1 110593580-110631474 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001976 Supported Tissue enriched 5 cerebral cortex: 20.7 thyroid gland: 3.8 -TOP3A TOP3, ZGRF7 ENSG00000177302 Topoisomerase (DNA) III alpha 17 18271428-18315007 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002449 Approved Expressed in all testis: 24.9 -CASKIN2 ANKS5B, FLJ21609, KIAA1139 ENSG00000177303 CASK interacting protein 2 17 75500261-75515583 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055836, HPA065308 Approved Nucleoplasm Mixed spleen: 29.3 -ZBTB38 CIBZ, FLJ35036, PPP1R171, ZNF921 ENSG00000177311 Zinc finger and BTB domain containing 38 3 141324213-141449792 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014865, HPA059378 Validated Nucleoplasm Expressed in all parathyroid gland: 129.7 -BEND2 CXorf20, MGC33653 ENSG00000177324 BEN domain containing 2 X 18162931-18220883 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA009420, HPA013142 Supported Tissue enriched 30 testis: 9.9 spleen: 0.3 -CCDC71 FLJ12800 ENSG00000177352 Coiled-coil domain containing 71 3 49162535-49166321 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047547 Uncertain Approved Nuclear membrane Expressed in all thyroid gland: 27.2 -C10orf71 FLJ45913 ENSG00000177354 Chromosome 10 open reading frame 71 10 49299193-49327487 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037962, HPA057556 Uncertain Group enriched 40 heart muscle: 28.8;parathyroid gland: 73.6;skeletal muscle: 97.7 prostate: 1.6 -OVOS2 ENSG00000177359 12 31111652-31206154 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 9 testis: 3.1 stomach: 0.3 -LRRN4CL ENSG00000177363 LRRN4 C-terminal like 11 62686402-62689899 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA050317 Approved Approved Nucleoplasm
Nuclear bodies Mixed endometrium: 16.8 -TIMM22 TEX4 ENSG00000177370 Translocase of inner mitochondrial membrane 22 homolog (yeast) 17 997117-1003671 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045138 Uncertain Mixed parathyroid gland: 4.3 -HIC1 ZBTB29, ZNF901 ENSG00000177374 Hypermethylated in cancer 1 17 2054154-2063241 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043372 Uncertain Supported Nucleoplasm
Cytosol Mixed endometrium: 16.2 -PPFIA3 KIAA0654, LPNA3, MGC126567, MGC126569 ENSG00000177380 Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 19 49119389-49151026 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043567, HPA050340 Supported Uncertain Nucleoli fibrillar center
Vesicles Group enriched 5 cerebral cortex: 21.6;skin: 20.2 parathyroid gland: 3.9 -MAGEF1 ENSG00000177383 Melanoma antigen family F1 3 184710367-184712002 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046899, HPA054190 Uncertain Approved Actin filaments Expressed in all cerebral cortex: 60.2 -UMODL1 ENSG00000177398 Uromodulin-like 1 21 42062959-42143453 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA067245 Uncertain Group enriched 7 fallopian tube: 1.9;testis: 1.7 small intestine: 0.2 -SAMD9L C7orf6, FLJ39885, KIAA2005 ENSG00000177409 Sterile alpha motif domain containing 9-like 7 93130055-93148369 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019461, HPA019465, HPA019488 Supported Approved Cytosol Mixed spleen: 53.3 -UBE2U MGC35130 ENSG00000177414 Ubiquitin-conjugating enzyme E2U (putative) 1 64203627-64267368 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 40 testis: 79.0 stomach: 1.9 -PAWR par-4, PAR4 ENSG00000177425 PRKC, apoptosis, WT1, regulator 12 79574979-79691097 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012640, CAB020779 Approved Validated Plasma membrane
Actin filaments Mixed endometrium: 45.3 -TGIF1 HPE4, TGIF ENSG00000177426 TGFB-induced factor homeobox 1 18 3411608-3459978 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062160 Supported Nucleoplasm Expressed in all epididymis: 159.9 -MIEF2 MGC23130, MiD49, SMCR7 ENSG00000177427 Mitochondrial elongation factor 2 17 18260534-18266552 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042334 Uncertain Expressed in all skeletal muscle: 14.1 -NAP1L5 DRLM ENSG00000177432 Nucleosome assembly protein 1-like 5 4 88695915-88698235 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058227 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 91.4 adrenal gland: 29.6 -NIM1K MGC42105, NIM1 ENSG00000177453 NIM1 serine/threonine protein kinase 5 43192071-43280850 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA007695 Uncertain Approved Cytosol Tissue enriched 8 cerebral cortex: 16.4 lung: 2.0 -CD19 ENSG00000177455 CD19 molecule 16 28931939-28939346 CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016110 Supported Group enriched 11 appendix: 38.8;lymph node: 85.0;spleen: 48.2;tonsil: 70.8 urinary bladder: 5.7 -ERICH5 C8orf47, FLJ39553 ENSG00000177459 Glutamate-rich 5 8 98064311-98093610 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA025070, HPA025293, HPA027233 Supported Approved Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced 0 fallopian tube: 13.6;gallbladder: 13.8 stomach: 9.1 -OR2T8 OR2T8P ENSG00000177462 Olfactory receptor, family 2, subfamily T, member 8 1 247921018-247921956 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 thyroid gland: 1.2 testis: 0.4 -NR2C2 hTAK1, TAK1, TR2R1, TR4 ENSG00000177463 Nuclear receptor subfamily 2, group C, member 2 3 14947584-15053600 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006313 Approved Validated Nucleoplasm Expressed in all testis: 38.8 -GPR4 ENSG00000177464 G protein-coupled receptor 4 19 45589764-45602208 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014278 Uncertain Mixed adipose tissue: 10.3 -ACOT4 FLJ31235, PTE-Ib, PTE2B ENSG00000177465 Acyl-CoA thioesterase 4 14 73591706-73596496 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000779 Approved Tissue enhanced 0 kidney: 8.9 liver: 4.9 -OLIG3 Bhlhb7, bHLHe20 ENSG00000177468 Oligodendrocyte transcription factor 3 6 137492202-137494250 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA018303, CAB024865 Uncertain Not detected esophagus: 0.1 -PTRF cavin-1, CAVIN1 ENSG00000177469 Polymerase I and transcript release factor 17 42402452-42423517 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049838, HPA074213 Supported Supported Vesicles
Plasma membrane Expressed in all adipose tissue: 342.2 -OR2G3 ENSG00000177476 Olfactory receptor, family 2, subfamily G, member 3 1 247605586-247606515 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -ARIH2 TRIAD1 ENSG00000177479 Ariadne RBR E3 ubiquitin protein ligase 2 3 48918821-48986382 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067381, HPA069715, HPA070963 Validated Nucleoplasm Expressed in all testis: 49.7 -RBM44 FLJ40411 ENSG00000177483 RNA binding motif protein 44 2 237798389-237842808 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003298 Supported Tissue enriched 67 testis: 35.2 lung: 0.5 -ZBTB33 kaiso, WUGSC:H_DJ525N14.1, ZNF-kaiso, ZNF348 ENSG00000177485 Zinc finger and BTB domain containing 33 X 120250752-120258398 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000755, CAB001980, HPA005732 Approved Validated Nucleus
Plasma membrane
Cytosol Expressed in all parathyroid gland: 23.0 -OR2G2 ENSG00000177489 Olfactory receptor, family 2, subfamily G, member 2 1 247588360-247589313 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -ZBED2 MGC10796 ENSG00000177494 Zinc finger, BED-type containing 2 3 111592900-111595443 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA029786 Uncertain Approved Nuclear bodies
Mitochondria
Cytosol Tissue enhanced 0 fallopian tube: 30.1;thyroid gland: 112.7 lung: 15.0 -VCX2 VCX-2r ENSG00000177504 Variable charge, X-linked 2 X 8169944-8171267 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044642, HPA044996, HPA049357 Uncertain Tissue enriched 32 testis: 3.2 adipose tissue: 0.0 -IRX3 IRX-1 ENSG00000177508 Iroquois homeobox 3 16 54283304-54286763 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA062522 Approved Vesicles Tissue enhanced 0 breast: 95.2 skin: 70.3 -ST8SIA3 SIAT8C ENSG00000177511 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 18 57350813-57371731 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA063398, HPA066783 Supported Supported Golgi apparatus Tissue enriched 7 cerebral cortex: 31.9 adrenal gland: 4.8 -RPRM FLJ90327, REPRIMO ENSG00000177519 Reprimo, TP53 dependent G2 arrest mediator candidate 2 153477338-153478808 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 21.3;endometrium: 21.9 smooth muscle: 17.3 -OR2B11 ENSG00000177535 Olfactory receptor, family 2, subfamily B, member 11 1 247451029-247451982 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA047459 Uncertain Not detected adipose tissue: 0.7 -SLC25A22 EIEE3, FLJ13044, GC1, NET44 ENSG00000177542 Solute carrier family 25 (mitochondrial carrier: glutamate), member 22 11 790475-798333 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014662 Approved Validated Nucleoplasm
Mitochondria Tissue enriched 6 cerebral cortex: 89.9 testis: 15.2 -RABEP2 FLJ23282, FRA ENSG00000177548 Rabaptin, RAB GTPase binding effector protein 2 16 28904421-28936526 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047641 Approved Supported Vesicles
Cytosol Expressed in all lymph node: 58.0 -NHLH2 bHLHa34, HEN2, NSCL2 ENSG00000177551 Nescient helix loop helix 2 1 115836377-115843917 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA055238 Uncertain Approved Nucleoplasm
Nuclear bodies Tissue enhanced 0 skin: 3.9 cerebral cortex: 0.8 -ATOX1 HAH1 ENSG00000177556 Antioxidant 1 copper chaperone 5 151742316-151772532 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055036 Approved Nucleoplasm
Plasma membrane Expressed in all thyroid gland: 151.1 -FAM187B FLJ25660, TMEM162 ENSG00000177558 Family with sequence similarity 187, member B 19 35224800-35228729 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 200 testis: 44.3 spleen: 0.2 -TBL1XR1 C21, DC42, FLJ12894, IRA1, TBLR1 ENSG00000177565 Transducin (beta)-like 1 X-linked receptor 1 3 177019355-177197396 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019182 Supported Approved Nucleoplasm Expressed in all thyroid gland: 61.2 -SAMD12 FLJ39458 ENSG00000177570 Sterile alpha motif domain containing 12 8 118189459-118621995 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA024634 Uncertain Approved Golgi apparatus
Cytosol Mixed thyroid gland: 14.0 -CD163 M130, MM130 ENSG00000177575 CD163 molecule 12 7470813-7503893 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002432, HPA046404, HPA051974 Supported Approved Plasma membrane Mixed appendix: 224.6 -C18orf32 FLJ23458 ENSG00000177576 Chromosome 18 open reading frame 32 18 49477250-49487252 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA040921 Approved Approved Nucleoplasm
Vesicles Expressed in all cerebral cortex: 120.0 -PIDD1 DKFZp434D229, LRDD, MGC16925, PIDD ENSG00000177595 P53-induced death domain protein 1 11 799179-809753 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012647, HPA055473 Supported Approved Golgi apparatus
Cytosol Mixed bone marrow: 4.7 -ZNF491 FLJ34791 ENSG00000177599 Zinc finger protein 491 19 11797667-11809622 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed parathyroid gland: 3.5 -RPLP2 D11S2243E, LP2, MGC71408, P2, RPP2 ENSG00000177600 Ribosomal protein, large, P2 11 809647-812880 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053635 Approved Expressed in all ovary: 1165.2 -GSG2 haspin ENSG00000177602 Germ cell associated 2 (haspin) 17 3723903-3726699 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027422, HPA030698 Approved Supported Nucleus Tissue enhanced 0 testis: 13.2 tonsil: 5.1 -JUN AP-1, c-Jun ENSG00000177606 Jun proto-oncogene 1 58780788-58784327 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003801, CAB007780, HPA059474 Supported Validated Nucleoplasm Expressed in all thyroid gland: 312.9 -CSTF2T CstF-64T, DKFZp434C1013, KIAA0689 ENSG00000177613 Cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 10 51695487-51699591 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039216, HPA062021 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 37.2 -PGBD5 DKFZp761A0620, FLJ11413 ENSG00000177614 PiggyBac transposable element derived 5 1 230314482-230425729 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065010 Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 40.2;cervix, uterine: 28.9 adrenal gland: 12.7 -C12orf54 MGC35033 ENSG00000177627 Chromosome 12 open reading frame 54 12 48482503-48496512 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039919 Uncertain Tissue enriched 63 testis: 85.7 tonsil: 1.3 -GBA GBA1, GLUC ENSG00000177628 Glucosidase, beta, acid 1 155234452-155244699 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006667, CAB037171, CAB037289 Supported Expressed in all parathyroid gland: 270.9 -ACAD9 MGC14452, NPD002 ENSG00000177646 Acyl-CoA dehydrogenase family, member 9 3 128879596-128916067 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037716, HPA046720 Supported Validated Mitochondria Expressed in all skin: 52.8 -IL17RA CD217, CDw217, hIL-17R, IL-17RA, IL17R ENSG00000177663 Interleukin 17 receptor A 22 17084954-17115694 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB024996 Supported Approved Nucleoplasm
Cytosol Mixed bone marrow: 20.7 -PNPLA2 ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2 ENSG00000177666 Patatin-like phospholipase domain containing 2 11 818902-825573 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055173, HPA062602 Validated Nucleoplasm
Lipid droplets Tissue enriched 13 adipose tissue: 419.8 skeletal muscle: 33.4 -MBOAT4 FKSG89, GOAT, OACT4 ENSG00000177669 Membrane bound O-acyltransferase domain containing 4 8 30131824-30144686 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044509 Supported Golgi apparatus Tissue enhanced 0 fallopian tube: 3.0;stomach: 3.5 gallbladder: 1.6 -C2orf57 MGC35154 ENSG00000177673 Chromosome 2 open reading frame 57 2 231592901-231594283 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049917, HPA056433 Supported Tissue enriched 748 testis: 120.2 fallopian tube: 0.1 -AGTRAP ATRAP ENSG00000177674 Angiotensin II receptor-associated protein 1 11736084-11754802 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044120 Approved Supported Vesicles Expressed in all prostate: 88.0 -CD163L1 CD163B, M160 ENSG00000177675 CD163 molecule-like 1 12 7346685-7479897 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015663 Supported Approved Nucleoplasm
Centrosome
Cytosol Tissue enhanced 0 spleen: 43.9 rectum: 24.5 -SRRM3 FLJ37078 ENSG00000177679 Serine/arginine repetitive matrix 3 7 76201900-76287288 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA019337 Uncertain Approved Plasma membrane
Intermediate filaments
Microtubules Group enriched 10 adrenal gland: 2.7;cerebral cortex: 8.5;testis: 1.8 stomach: 0.4 -THAP5 DKFZp313O1132 ENSG00000177683 THAP domain containing 5 7 108554543-108569750 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043170, HPA051488 Approved Validated Nucleus Expressed in all testis: 46.5 -DEFB114 DEFB-14 ENSG00000177684 Defensin, beta 114 6 49960249-49964105 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052126 Uncertain Tissue enriched 1187 epididymis: 118.7 adipose tissue: 0.0 -CRACR2B EFCAB4A, MGC45840 ENSG00000177685 Calcium release activated channel regulator 2B 11 826144-831991 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046217 Approved Tissue enhanced 0 salivary gland: 120.7 stomach: 57.1 -SUMO4 dJ281H8.4, IDDM5, SMT3H4 ENSG00000177688 Small ubiquitin-like modifier 4 6 149400227-149401292 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042123, HPA048064 Uncertain Approved Nucleoplasm
Nuclear bodies Not detected liver: 0.6 -MAGEB10 FLJ32965 ENSG00000177689 Melanoma antigen family B10 X 27807990-27823014 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000611 Uncertain Tissue enriched 10 testis: 4.6 skin: 0.4 -DNAJC28 C21orf55, C21orf78 ENSG00000177692 DnaJ (Hsp40) homolog, subfamily C, member 28 21 33485530-33491720 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA018003, HPA030076 Approved Tissue enhanced 0 testis: 8.2 thyroid gland: 4.1 -OR4F4 OR4F18 ENSG00000177693 Olfactory receptor, family 4, subfamily F, member 4 15 101922042-101923095 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -NAALADL2 ENSG00000177694 N-acetylated alpha-linked acidic dipeptidase-like 2 3 174438573-175810552 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012413, HPA017425, CAB025586 Approved Tissue enhanced 0 parathyroid gland: 42.8 cervix: 11.8 -CD151 PETA-3, RAPH, SFA-1, TSPAN24 ENSG00000177697 CD151 molecule (Raph blood group) 11 832843-839831 Blood group antigen proteins, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002428, HPA011906 Supported Expressed in all smooth muscle: 356.5 -POLR2L hRPB7.6, hsRPB10b, RBP10, RPABC5, RPB10beta, RPB7.6 ENSG00000177700 Polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 11 837356-842545 Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all adipose tissue: 67.7 -FAM20C DKFZp547D065, DMP4, IMAGE:4942737 ENSG00000177706 Family with sequence similarity 20, member C 7 192969-260745 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019823 Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all kidney: 38.1 -PVRL3 CD113, CDw113, DKFZP566B0846, nectin-3, PPR3, PVRR3 ENSG00000177707 Poliovirus receptor-related 3 3 111070071-111275563 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009869, HPA011038 Approved Approved Microtubule organizing center Tissue enhanced 0 testis: 99.0 thyroid gland: 74.6 -SLC35G5 AMAC, AMAC1L2 ENSG00000177710 Solute carrier family 35, member G5 8 11330888-11332208 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 1.5 spleen: 0.4 -ANXA2R AXIIR, C5orf39 ENSG00000177721 Annexin A2 receptor 5 43039081-43043170 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051482 Uncertain Approved Nucleoplasm
Aggresome
Cytosol
Cytoplasmic bodies Tissue enhanced 0 lymph node: 22.2 spleen: 15.7 -TMEM94 KIAA0195 ENSG00000177728 Transmembrane protein 94 17 75441159-75500090 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008423, HPA050660 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all cerebral cortex: 54.3 -FLII FLI, Fli1, FLIL, MGC39265 ENSG00000177731 Flightless I actin binding protein 17 18244836-18258916 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007084, HPA008903, CAB016132 Approved Supported Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all skeletal muscle: 82.5 -SOX12 SOX22 ENSG00000177732 SRY (sex determining region Y)-box 12 20 325401-330224 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055052, HPA061627 Supported Nucleoplasm Mixed cerebral cortex: 10.3 -HNRNPA0 hnRNPA0, HNRPA0 ENSG00000177733 Heterogeneous nuclear ribonucleoprotein A0 5 137745651-137754376 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036569, HPA059404 Supported Validated Nucleoplasm Expressed in all ovary: 32.7 -YIPF7 FinGER9, FLJ39576 ENSG00000177752 Yip1 domain family, member 7 4 44622065-44678556 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030642 Uncertain Tissue enriched 42 skeletal muscle: 29.6 esophagus: 0.7 -MYOZ1 CS-2, FATZ, MYOZ ENSG00000177791 Myozenin 1 10 73631654-73641757 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037848, HPA038437 Supported Tissue enriched 37 skeletal muscle: 2059.3 esophagus: 55.0 -TMEM78 FLJ40168 ENSG00000177800 Transmembrane protein 78 1 229249636-229251810 Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA042351 Uncertain Not detected epididymis: 0.5 -KCNJ10 Kir1.2, Kir4.1 ENSG00000177807 Potassium channel, inwardly rectifying subfamily J, member 10 1 160037467-160070248 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 cerebral cortex: 120.1;kidney: 27.8 spleen: 13.3 -CHID1 FLJ42707, MGC3234 ENSG00000177830 Chitinase domain containing 1 11 867860-915058 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039374 Uncertain Uncertain Nucleoplasm
Intermediate filaments Expressed in all epididymis: 108.1 -PCDHB9 PCDH-BETA9, PCDH3H ENSG00000177839 Protocadherin beta 9 5 141187127-141191541 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA013445, HPA029441 Uncertain Tissue enhanced 0 cerebral cortex: 7.9 ovary: 2.5 -ZNF620 MGC50836 ENSG00000177842 Zinc finger protein 620 3 40505992-40518736 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA031452 Uncertain Approved Plasma membrane Mixed thyroid gland: 6.0 -ZNF518A KIAA0335, ZNF518 ENSG00000177853 Zinc finger protein 518A 10 96129715-96205288 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029049 Approved Nucleus Mixed testis: 30.6 -TMEM187 CXorf12, DXS9878E, ITBA1 ENSG00000177854 Transmembrane protein 187 X 153972327-153983195 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA038134 Uncertain Approved Nucleoli
Cytosol Expressed in all fallopian tube: 11.2 -SVBP CCDC23, MGC45441 ENSG00000177868 Small vasohibin binding protein 1 42807052-42817252 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008507 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all testis: 82.8 -ZNF619 FLJ90764 ENSG00000177873 Zinc finger protein 619 3 40477113-40490236 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045094 Uncertain Approved Nucleoplasm
Intermediate filaments Mixed parathyroid gland: 7.7 -CCDC184 C12orf68, LOC387856 ENSG00000177875 Coiled-coil domain containing 184 12 48183584-48185926 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039947, HPA041715 Uncertain Approved Mitochondria
Cytosol Tissue enhanced 0 cerebral cortex: 15.4 adrenal gland: 6.7 -AP3S1 CLAPS3 ENSG00000177879 Adaptor-related protein complex 3, sigma 1 subunit 5 115841481-115914081 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049270 Uncertain Approved Vesicles Expressed in all epididymis: 39.1 -GRB2 NCKAP2 ENSG00000177885 Growth factor receptor-bound protein 2 17 75318076-75405709 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002589, HPA030749, HPA030750 Approved Supported Nucleus Expressed in all appendix: 138.6 -ZBTB41 DKFZp686C06120, FLJ36199, FRBZ1, ZNF924 ENSG00000177888 Zinc finger and BTB domain containing 41 1 197153680-197200542 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034841, HPA034842 Uncertain Approved Nucleus
Nuclear membrane
Cytosol Mixed thyroid gland: 12.7 -UBE2N MGC8489, UBC13, UbcH-ben ENSG00000177889 Ubiquitin-conjugating enzyme E2N 12 93405673-93442262 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044976 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all testis: 252.8 -ARL6IP6 MGC33864 ENSG00000177917 ADP-ribosylation factor-like 6 interacting protein 6 2 152717893-152761253 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014743 Approved Approved Nuclear membrane
Cytosol Mixed placenta: 7.5 -ZNF354C KID3 ENSG00000177932 Zinc finger protein 354C 5 179060415-179083537 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA030904 Uncertain Supported Nuclear membrane
Cytosol Mixed ovary: 9.2 -CAPZA3 CAPPA3, Gsg3 ENSG00000177938 Capping protein (actin filament) muscle Z-line, alpha 3 12 18738101-18739187 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038688 Supported Tissue enriched 99 testis: 278.9 skin: 2.8 -MAMDC4 AEGP, DKFZp434M1411 ENSG00000177943 MAM domain containing 4 9 136850943-136860799 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB026377, HPA059977 Approved Approved Nucleoplasm
Cytosol Mixed spleen: 5.7 -CENPBD1 MGC16385 ENSG00000177946 CENPB DNA-binding domains containing 1 16 89969791-89972534 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052759, HPA060522 Uncertain Approved Nucleoli
Vesicles Mixed parathyroid gland: 11.0 -ODF3 CT135, hSHIPPO, SHIPPO1 ENSG00000177947 Outer dense fiber of sperm tails 3 11 196738-200261 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038919, HPA039241 Uncertain Tissue enriched 94 testis: 9.3 epididymis: 0.0 -BET1L GOLIM3, GS15 ENSG00000177951 Bet1 golgi vesicular membrane trafficking protein-like 11 167784-207428 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039819 Approved Approved Nucleus
Golgi apparatus Expressed in all parathyroid gland: 74.3 -RPS27 MPS-1, MPS1, S27 ENSG00000177954 Ribosomal protein S27 1 153990759-153992150 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066851 Approved Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 11931.0 -RIC8A synembryn, synembryn-A ENSG00000177963 RIC8 guanine nucleotide exchange factor A 11 207511-215113 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041491, CAB046012 Approved Supported Cytosol Expressed in all smooth muscle: 71.5 -IMP3 BRMS2, C15orf12, FLJ10968, MRPS4 ENSG00000177971 IMP3, U3 small nucleolar ribonucleoprotein 15 75639085-75648706 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060955, HPA061177 Validated Nucleus
Nucleoli Expressed in all spleen: 48.4 -ASB8 FLJ21255, MGC5540 ENSG00000177981 Ankyrin repeat and SOCS box containing 8 12 48147788-48181213 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003299 Approved Expressed in all skeletal muscle: 98.2 -LCN15 PRO6093, UNQ2541 ENSG00000177984 Lipocalin 15 9 136759634-136766255 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060584 Approved Tissue enhanced 0 duodenum: 12.4;seminal vesicle: 4.8;small intestine: 4.1 colon: 2.8 -ODF3B ENSG00000177989 Outer dense fiber of sperm tails 3B 22 50529710-50532580 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062837 Approved Tissue enhanced 0 fallopian tube: 74.1 appendix: 37.8 -DPY19L2 FLJ32949, SPATA34 ENSG00000177990 Dpy-19-like 2 (C. elegans) 12 63558913-63668939 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071264 Approved Nucleus
Mitochondria Tissue enriched 8 testis: 111.5 parathyroid gland: 14.6 -SPATA31E1 C9orf79, FAM75E1, FLJ35866 ENSG00000177992 SPATA31 subfamily E, member 1 9 87882826-87888899 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024253 Supported Tissue enriched 100 testis: 9.9 adipose tissue: 0.0 -C2orf73 FLJ40298 ENSG00000177994 Chromosome 2 open reading frame 73 2 54330034-54383742 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055221, HPA059596 Uncertain Tissue enriched 7 testis: 83.2 fallopian tube: 12.0 -GPR150 PGR11 ENSG00000178015 G protein-coupled receptor 150 5 95620078-95622142 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA026635 Uncertain Tissue enhanced 0 cerebral cortex: 1.3;parathyroid gland: 2.0 pancreas: 1.0 -TSPYL6 ENSG00000178021 TSPY-like 6 2 54253184-54256272 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA034699, HPA034700 Supported Approved Nucleoli
Centrosome
Cytosol Tissue enriched 389 testis: 38.8 epididymis: 0.0 -LRRC75B C22orf36, FAM211B, MGC131773 ENSG00000178026 Leucine rich repeat containing 75B 22 24585620-24593208 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA002540 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 testis: 2.2 cerebral cortex: 1.3 -DMAP1 DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, MEAF2, SWC4 ENSG00000178028 DNA methyltransferase 1 associated protein 1 1 44213455-44220681 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028419, CAB033018 Uncertain Supported Nucleoplasm
Cytosol Expressed in all adrenal gland: 40.5 -ADAMTSL1 ADAMTSR1, C9orf94, FLJ35283 ENSG00000178031 ADAMTS-like 1 9 18473894-18910950 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057437 Uncertain Tissue enhanced 0 endometrium: 20.7 smooth muscle: 16.1 -FAM26E C6orf188, dJ493F7.3, MGC45451 ENSG00000178033 Family with sequence similarity 26, member E 6 116511646-116524792 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA034969, HPA034970 Uncertain Approved Golgi apparatus Mixed placenta: 6.4 -IMPDH2 ENSG00000178035 IMP (inosine 5'-monophosphate) dehydrogenase 2 3 49024325-49029408 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001400, CAB020717 Approved Validated Cytosol
Rods & Rings Expressed in all ovary: 421.1 -ALS2CL DKFZp686I0110, FLJ36525, RN49018 ENSG00000178038 ALS2 C-terminal like 3 46668997-46693704 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046465, HPA048301 Uncertain Tissue enhanced 0 skin: 51.4 esophagus: 23.9 -MLF1 ENSG00000178053 Myeloid leukemia factor 1 3 158571163-158607252 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069479 Approved Nucleoplasm
Cytosol Tissue enriched 6 testis: 667.3 heart muscle: 104.2 -PRSS42 TESSP2 ENSG00000178055 Protease, serine, 42 3 46829542-46834095 Enzymes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046925 Uncertain Group enriched 6 epididymis: 4.7;heart muscle: 7.1;parathyroid gland: 3.1;skeletal muscle: 8.4;testis: 2.0;thyroid gland: 1.8 cervix: 0.7 -NDUFAF3 2P1, C3orf60, DKFZP564J0123, E3-3, MGC10527 ENSG00000178057 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 3 49020459-49023495 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035376, HPA035377 Supported Expressed in all testis: 287.4 -C2orf69 FLJ38973 ENSG00000178074 Chromosome 2 open reading frame 69 2 199911256-199955935 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045225 Uncertain Expressed in all testis: 26.5 -GRAMD1C DKFZp434C0328 ENSG00000178075 GRAM domain containing 1C 3 113828182-113947174 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012316 Approved Uncertain Plasma membrane
Cytosol Mixed testis: 28.3 -STAP2 BKS, STAP-2 ENSG00000178078 Signal transducing adaptor family member 2 19 4324043-4342786 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002375, HPA027761 Approved Mixed duodenum: 81.7 -HTR3C ENSG00000178084 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 3 184053047-184060671 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lung: 1.9 duodenum: 0.4 -TSSK6 CT72, FLJ24002, SSTK ENSG00000178093 Testis-specific serine kinase 6 19 19512418-19515685 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 24 testis: 18.7 spleen: 0.7 -BOLA1 CGI-143 ENSG00000178096 BolA family member 1 1 149887890-149900798 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007005 Approved Expressed in all duodenum: 16.0 -PDE4DIP CMYA2, KIAA0454, KIAA0477, MMGL ENSG00000178104 Phosphodiesterase 4D interacting protein 1 148808181-149048286 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008162, HPA012678 Uncertain Supported Golgi apparatus Expressed in all skeletal muscle: 769.6 -DDX10 HRH-J8 ENSG00000178105 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 11 108665025-108940930 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004691 Approved Approved Nucleoli Expressed in all testis: 29.1 -GOLGA8Q ENSG00000178115 Golgin A8 family, member Q 15 30552078-30562501 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 7 thyroid gland: 18.6 parathyroid gland: 2.6 -PPP1R42 dtr, LRRC67, TLLR ENSG00000178125 Protein phosphatase 1, regulatory subunit 42 8 66964099-67056604 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA024313, HPA027983, HPA028628 Uncertain Group enriched 19 fallopian tube: 7.7;testis: 15.5 lung: 0.6 -NDUFV2 CI-24k ENSG00000178127 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 18 9102630-9134345 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003404, HPA077896 Supported Approved Supported Mitochondria Expressed in all skeletal muscle: 190.9 -DALRD3 FLJ10496 ENSG00000178149 DALR anticodon binding domain containing 3 3 49015488-49022293 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036862 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all fallopian tube: 58.8 -ZNF114 MGC17986 ENSG00000178150 Zinc finger protein 114 19 48172318-48287608 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025019, HPA029553 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 thyroid gland: 10.3 parathyroid gland: 3.9 -ZNF518B KIAA1729 ENSG00000178163 Zinc finger protein 518B 4 10439874-10457410 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA031215, HPA031216 Approved Approved Nucleus Mixed testis: 16.9 -AMER3 FAM123C, FLJ38377 ENSG00000178171 APC membrane recruitment protein 3 2 130755435-130768134 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045593, HPA054230 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Tissue enriched 9 cerebral cortex: 7.0 adrenal gland: 0.8 -SPINK6 BUSI2, MGC21394, UNQ844 ENSG00000178172 Serine peptidase inhibitor, Kazal type 6 5 148202794-148215137 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011039 Uncertain Not detected epididymis: 0.9 -ZNF366 FLJ39796 ENSG00000178175 Zinc finger protein 366 5 72442652-72507727 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA023128, HPA023526 Uncertain Mixed placenta: 10.2 -LCORL FLJ30696, MLR1 ENSG00000178177 Ligand dependent nuclear receptor corepressor-like 4 17841199-18021876 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028794, HPA028795, HPA060033 Uncertain Supported Nucleoplasm
Nuclear membrane Mixed testis: 11.6 -PARD6G PAR-6G, PAR6gamma ENSG00000178184 Par-6 family cell polarity regulator gamma 18 80157232-80247546 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA047017 Uncertain Approved Plasma membrane Tissue enhanced 0 skin: 45.0 thyroid gland: 30.1 -ZNF454 FLJ37444 ENSG00000178187 Zinc finger protein 454 5 178941191-178966433 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA024556 Uncertain Mixed testis: 4.0 -SH2B1 FLJ30542, SH2B ENSG00000178188 SH2B adaptor protein 1 16 28846600-28874212 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA076175 Approved Vesicles Expressed in all parathyroid gland: 103.5 -ZC3H12D C6orf95, dJ281H8.1, MCPIP4 ENSG00000178199 Zinc finger CCCH-type containing 12D 6 149446795-149485061 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036897 Uncertain Supported Nucleoplasm
Cytoplasmic bodies Tissue enhanced 0 appendix: 9.9;lymph node: 11.7;tonsil: 12.1 spleen: 6.1 -VN1R1 V1RL1, VNR19I1, ZVNH1, ZVNR1 ENSG00000178201 Vomeronasal 1 receptor 1 19 57454790-57457142 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062209 Uncertain Nucleus
Vesicles Mixed epididymis: 2.8 -KDELC2 MGC33424 ENSG00000178202 KDEL (Lys-Asp-Glu-Leu) containing 2 11 108472105-108498432 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039315, HPA039817, HPA066134 Uncertain Supported Nucleoplasm
Vesicles Expressed in all parathyroid gland: 61.1 -PLEC EBS1, PCN, PLEC1, PLTN ENSG00000178209 Plectin 8 143915147-143976734 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003847, HPA025967, HPA029906 Supported Validated Intermediate filaments
Focal adhesion sites
Cytosol Expressed in all skeletal muscle: 94.9 -SH2D4B ENSG00000178217 SH2 domain containing 4B 10 80537902-80646560 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040022 Uncertain Not detected epididymis: 0.6 -RNF212 FLJ38841, LOC285498 ENSG00000178222 Ring finger protein 212 4 1056250-1113562 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057527 Uncertain Mixed thyroid gland: 5.8 -PRSS36 FLJ90661 ENSG00000178226 Protease, serine, 36 16 31138925-31150094 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036079 Uncertain Mixed skin: 1.2 -ZNF543 DKFZp434H055 ENSG00000178229 Zinc finger protein 543 19 57320509-57330776 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA029736, HPA057665 Uncertain Approved Nuclear speckles
Cytosol Mixed ovary: 6.0 -TMEM151B bA444E17.5, C6orf137, TMEM193 ENSG00000178233 Transmembrane protein 151B 6 44270466-44307506 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055167 Uncertain Tissue enriched 10 cerebral cortex: 40.1 adrenal gland: 4.0 -GALNT11 GalNAc-T11 ENSG00000178234 Polypeptide N-acetylgalactosaminyltransferase 11 7 152025674-152122347 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039330 Uncertain Expressed in all kidney: 241.1 -SLITRK1 KIAA1910, LRRC12 ENSG00000178235 SLIT and NTRK-like family, member 1 13 83877205-83882393 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012414 Supported Tissue enriched 82 cerebral cortex: 23.9 seminal vesicle: 0.2 -WDR6 ENSG00000178252 WD repeat domain 6 3 49007062-49015953 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042622 Approved Supported Plasma membrane
Cytosol Expressed in all parathyroid gland: 199.7 -PRM3 ENSG00000178257 Protamine 3 16 11273218-11273641 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 23 testis: 42.5 bone marrow: 1.8 -TNP2 TP2 ENSG00000178279 Transition protein 2 (during histone to protamine replacement) 16 11267748-11269533 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 385 testis: 38.5 adipose tissue: 0.0 -SPAG11A EDDM2A, HE2 ENSG00000178287 Sperm associated antigen 11A 8 7847876-7868867 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 10595 epididymis: 6163.8 seminal vesicle: 0.5 -GEN1 FLJ40869, Gen ENSG00000178295 GEN1 Holliday junction 5' flap endonuclease 2 17753858-17788941 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020078, HPA021141 Uncertain Approved Nucleoplasm Mixed epididymis: 19.8 -TMPRSS9 ENSG00000178297 Transmembrane protease, serine 9 19 2389771-2426239 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051483 Uncertain Tissue enhanced 0 spleen: 2.3 testis: 1.7 -AQP11 ENSG00000178301 Aquaporin 11 11 77589391-77610355 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042879 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 duodenum: 24.8;small intestine: 23.6 adrenal gland: 10.1 -TMEM11 C17orf35, PM1, PMI ENSG00000178307 Transmembrane protein 11 17 21197280-21214624 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051795, HPA062854 Uncertain Supported Mitochondria Mixed skeletal muscle: 3.6 -ZNF354B FLJ25008, KID2 ENSG00000178338 Zinc finger protein 354B 5 178859953-178888122 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029056 Approved Approved Nucleoplasm Expressed in all placenta: 19.7 -KCNG2 KCNF2, Kv6.2 ENSG00000178342 Potassium channel, voltage gated modifier subfamily G, member 2 18 79863668-79900184 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level No evidence Evidence at protein level HPA048628 Approved Not detected cerebral cortex: 0.4 -SHISA3 hShisa3 ENSG00000178343 Shisa family member 3 4 42397839-42402487 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054754 Approved Lipid droplets
Cytosol Tissue enhanced 0 kidney: 24.9 lymph node: 8.8 -OR2D3 ENSG00000178358 Olfactory receptor, family 2, subfamily D, member 3 11 6920974-6922043 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA052551 Uncertain Not detected adipose tissue: 0.0 -CALML3 CLP ENSG00000178363 Calmodulin-like 3 10 5524009-5526771 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010070, HPA044999 Approved Tissue enhanced 0 esophagus: 166.4;skin: 42.7 tonsil: 23.4 -CALML5 CLSP ENSG00000178372 Calmodulin-like 5 10 5498697-5499555 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040725 Supported Approved Plasma membrane
Cytosol Group enriched 8 salivary gland: 262.7;skin: 651.2 breast: 55.1 -ZFAND2A AIRAP ENSG00000178381 Zinc finger, AN1-type domain 2A 7 1152071-1160759 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA019469 Approved Expressed in all bone marrow: 50.1 -PLEKHM3 DAPR, PLEKHM1L ENSG00000178385 Pleckstrin homology domain containing, family M, member 3 2 207828303-208025560 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035046 Uncertain Approved Vesicles
Cytosol Mixed parathyroid gland: 16.5 -ZNF223 ENSG00000178386 Zinc finger protein 223 19 44051367-44067991 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA067823 Approved Nucleus
Mitochondria Mixed thyroid gland: 10.6 -HTR1A 5-HT1A, ADRB2RL1, ADRBRL1 ENSG00000178394 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 5 63960356-63962507 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA018073 Uncertain Group enriched 10 cerebral cortex: 1.9;ovary: 3.9 testis: 0.2 -CCDC185 C1orf65, FLJ35728 ENSG00000178395 Coiled-coil domain containing 185 1 223393417-223395470 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027518 Uncertain Tissue enriched 198 testis: 25.2 cerebral cortex: 0.1 -FAM220A C7orf70, MGC12966, SIPAR ENSG00000178397 Family with sequence similarity 220, member A 7 6329409-6348981 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055050 Approved Vesicles Expressed in all testis: 102.0 -DNAJC22 FLJ13236, wus ENSG00000178401 DnaJ (Hsp40) homolog, subfamily C, member 22 12 49346917-49357546 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039953 Approved Vesicles Mixed thyroid gland: 17.9 -NEUROG2 Atoh4, bHLHa8, Math4A, ngn-2, NGN2 ENSG00000178403 Neurogenin 2 4 112513516-112516172 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB012342 Uncertain Tissue enhanced 0 testis: 1.5 cerebral cortex: 0.4 -CEP295NL DDC8, KIAA1731NL ENSG00000178404 CEP295 N-terminal like 17 78870910-78903217 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023609, HPA024619, HPA025717 Uncertain Approved Vesicles Tissue enriched 46 testis: 40.4 bone marrow: 0.8 -BEND3 KIAA1553 ENSG00000178409 BEN domain containing 3 6 107065182-107115269 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017891, HPA062067 Uncertain Approved Nucleoplasm Mixed testis: 2.7 -NT5DC1 dJ486I3.1, MGC24302, NT5C2L1 ENSG00000178425 5'-nucleotidase domain containing 1 6 116100849-116249497 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030352 Uncertain Expressed in all thyroid gland: 47.1 -GLDC GCSP, NKH ENSG00000178445 Glycine dehydrogenase (decarboxylating) 9 6532464-6645650 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002318, HPA052887 Supported Supported Nucleus
Mitochondria Tissue enhanced 0 kidney: 58.8;liver: 39.3;placenta: 46.9 cerebral cortex: 18.7 -COX14 C12orf62, MGC14288 ENSG00000178449 COX14 cytochrome c oxidase assembly factor 12 50111979-50120457 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044618, HPA062014 Approved Supported Mitochondria Expressed in all kidney: 86.0 -MCMDC2 C8orf45, FLJ25692 ENSG00000178460 Minichromosome maintenance domain containing 2 8 66870749-66922048 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA026522 Approved Actin filaments Tissue enhanced 0 testis: 21.7 ovary: 5.2 -TUBAL3 FLJ21665 ENSG00000178462 Tubulin, alpha-like 3 10 5393098-5404830 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045900, HPA063394 Uncertain Tissue enhanced 0 duodenum: 25.1;small intestine: 31.7 colon: 12.0 -P4HTM EGLN4, FLJ20262, HIFPH4, P4H-TM, PH-4, PH4, PHD4 ENSG00000178467 Prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3 48989886-49007154 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007199 Supported Uncertain Vesicles
Cytosol Expressed in all fallopian tube: 49.9 -UCN3 SPC, UCNIII ENSG00000178473 Urocortin 3 10 5365009-5374692 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038281 Uncertain Tissue enhanced 0 duodenum: 9.5;small intestine: 7.6 stomach: 3.7 -DTX3 FLJ34766, RNF154 ENSG00000178498 Deltex 3, E3 ubiquitin ligase 12 57604622-57609804 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059654 Approved Approved Nucleus
Nucleoli
Golgi apparatus Expressed in all cerebral cortex: 103.1 -KLHL11 FLJ10572 ENSG00000178502 Kelch-like family member 11 17 41853545-41865431 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023021, HPA054269 Uncertain Tissue enhanced 0 testis: 22.4 cerebral cortex: 10.8 -AMBN ENSG00000178522 Ameloblastin (enamel matrix protein) 4 70592256-70607288 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Not detected cerebral cortex: 0.3 -CTXN1 FLJ25968 ENSG00000178531 Cortexin 1 19 7924485-7926166 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA016669 Uncertain Approved Nucleoplasm
Plasma membrane
Cell Junctions Tissue enhanced 0 cerebral cortex: 100.8 endometrium: 22.7 -SLC25A20 CAC, CACT ENSG00000178537 Solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 3 48856931-48898993 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016862, HPA029863 Approved Supported Mitochondria
Cytosol Expressed in all liver: 70.8 -CA8 CALS, CARP ENSG00000178538 Carbonic anhydrase VIII 8 60187347-60281412 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024748, CAB025545, CAB047309 Supported Tissue enriched 6 parathyroid gland: 103.6 epididymis: 17.1 -CD28 ENSG00000178562 CD28 molecule 2 203706475-203738912 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070003 Supported Tissue enhanced 0 lymph node: 32.9;placenta: 20.8 appendix: 19.2 -EPM2AIP1 FLJ11207, KIAA0766 ENSG00000178567 EPM2A (laforin) interacting protein 1 3 36985043-36993168 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 35.6 -ERBB4 ALS19, HER4 ENSG00000178568 Erb-b2 receptor tyrosine kinase 4 2 211375717-212538841 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB000276, HPA012016, CAB025522 Approved Tissue enhanced 0 fallopian tube: 17.6 cerebral cortex: 7.6 -MAF c-MAF ENSG00000178573 V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 16 79585843-79600714 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level CAB010296, HPA028289 Approved Tissue enhanced 0 parathyroid gland: 147.2 small intestine: 93.1 -CTNNBIP1 ICAT, MGC15093 ENSG00000178585 Catenin, beta interacting protein 1 1 9848276-9910336 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042617 Approved Plasma membrane
Cell Junctions
Mitochondria Expressed in all skin: 288.8 -OR6B3 OR6B3P, OR6B3Q ENSG00000178586 Olfactory receptor, family 6, subfamily B, member 3 2 240045077-240046072 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA047529 Uncertain Tissue enhanced 0 epididymis: 1.9 testis: 0.7 -DEFB125 DEFB-25 ENSG00000178591 Defensin, beta 125 20 87250-97094 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043095 Uncertain Group enriched 13 epididymis: 1.7;seminal vesicle: 1.4 testis: 0.1 -PSAPL1 ENSG00000178597 Prosaposin-like 1 (gene/pseudogene) 4 7432258-7434945 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038013, HPA038482 Approved Validated Cytosol Group enriched 7 skin: 78.5;stomach: 59.0 breast: 10.1 -OTOS OTOSP ENSG00000178602 Otospiralin 2 240139026-240144562 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 16 thyroid gland: 73.9 cerebral cortex: 4.6 -GTPBP6 FLJ20977, PGPL ENSG00000178605 GTP binding protein 6 (putative) X 304529-318819 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB034924, HPA035467, HPA055418 Approved Uncertain Mitochondria Expressed in all spleen: 26.7 -ERN1 IRE1, IRE1P ENSG00000178607 Endoplasmic reticulum to nucleus signaling 1 17 64039142-64130819 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009495, HPA027730 Supported Expressed in all adrenal gland: 53.7 -GPR35 ENSG00000178623 G protein-coupled receptor 35 2 240605431-240631259 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 duodenum: 42.6;small intestine: 43.2 colon: 18.8 -C10orf53 Em:AC069546.1 ENSG00000178645 Chromosome 10 open reading frame 53 10 49679651-49710261 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA037951 Approved Tissue enriched 61 testis: 43.3 fallopian tube: 0.7 -CSRNP3 FAM130A2, FLJ32093, PPP1R73, TAIP-2 ENSG00000178662 Cysteine-serine-rich nuclear protein 3 2 165469647-165689407 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA017905 Supported Approved Nucleus
Nucleoli Tissue enhanced 0 cerebral cortex: 16.2 endometrium: 4.6 -ZNF713 FLJ39963 ENSG00000178665 Zinc finger protein 713 7 55887475-55942225 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA059425, HPA062887 Uncertain Approved Nucleoli Mixed testis: 8.4 -PARP10 FLJ14464 ENSG00000178685 Poly (ADP-ribose) polymerase family, member 10 8 143977153-144012772 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028122, HPA052427 Approved Supported Nucleoli
Cytosol Expressed in all spleen: 57.5 -DYNAP C18orf26, FLJ39106 ENSG00000178690 Dynactin associated protein 18 54587757-54599493 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011148 Uncertain Tissue enriched 7 esophagus: 32.3 spleen: 4.4 -SUZ12 CHET9, JJAZ1, KIAA0160 ENSG00000178691 SUZ12 polycomb repressive complex 2 subunit 17 31937018-32001045 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057436 Approved Approved Nucleus
Nucleoli
Nuclear bodies Expressed in all testis: 50.5 -NSUN3 FLJ22609 ENSG00000178694 NOP2/Sun domain family, member 3 3 94062916-94128545 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036181, HPA057979 Uncertain Approved Nucleoplasm
Nuclear membrane Mixed testis: 8.0 -KCTD12 C13orf2, KIAA1778, PFET1 ENSG00000178695 Potassium channel tetramerization domain containing 12 13 76880166-76886390 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056987 Approved Mitochondria Expressed in all fallopian tube: 121.6 -DHFRL1 DHFRP4, FLJ16119 ENSG00000178700 Dihydrofolate reductase-like 1 3 94047836-94063389 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051465 Uncertain Supported Mitochondria Mixed parathyroid gland: 15.9 -RPP25 FLJ20374 ENSG00000178718 Ribonuclease P/MRP 25kDa subunit 15 74954416-74957464 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046900 Approved Supported Nucleoplasm
Microtubule organizing center Mixed ovary: 12.2 -GRINA HNRGW, LFG1, NMDARA1, TMBIM3 ENSG00000178719 Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 8 143990058-143993415 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036980, HPA036981 Approved Approved Nucleoli fibrillar center
Cytosol Expressed in all seminal vesicle: 261.5 -THBD CD141 ENSG00000178726 Thrombomodulin 20 23045633-23049741 Candidate cardiovascular disease genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002425, HPA002982 Supported Approved Nucleoplasm
Cytosol Expressed in all lung: 73.4 -GP5 CD42d ENSG00000178732 Glycoprotein V (platelet) 3 194394821-194398354 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 fallopian tube: 1.2;lymph node: 1.3 appendix: 0.9 -LMO7DN C13orf45 ENSG00000178734 LMO7 downstream neighbor 13 75871038-75883811 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052013 Uncertain Tissue enhanced 0 gallbladder: 1.4 testis: 0.7 -COX5A ENSG00000178741 Cytochrome c oxidase subunit Va 15 74919791-74938168 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027526 Supported Expressed in all skeletal muscle: 548.5 -STX19 MGC21382 ENSG00000178750 Syntaxin 19 3 94014369-94028610 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA030604 Uncertain Tissue enhanced 0 epididymis: 19.7 rectum: 14.9 -FAM132B C1QTNF15, CTRP15, FLJ37034 ENSG00000178752 Family with sequence similarity 132, member B 2 238158982-238168900 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA077259 Approved Endoplasmic reticulum
Microtubule organizing center Group enriched 8 testis: 17.1;thyroid gland: 40.6 appendix: 3.5 -FAM219B C15orf17, FLJ00005 ENSG00000178761 Family with sequence similarity 219, member B 15 74899987-74907121 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048929, HPA058064 Approved Approved Nucleoplasm
Golgi apparatus Mixed parathyroid gland: 20.3 -ZHX2 KIAA0854 ENSG00000178764 Zinc fingers and homeoboxes 2 8 122781394-122974512 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006769, HPA006996 Supported Expressed in all ovary: 32.7 -CPN2 ACBP ENSG00000178772 Carboxypeptidase N, polypeptide 2 3 194339765-194351328 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004732 Uncertain Tissue enriched 7 liver: 113.6 kidney: 15.5 -CPNE7 ENSG00000178773 Copine VII 16 89575768-89597246 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043359 Uncertain Tissue enhanced 0 epididymis: 23.1 cerebral cortex: 9.8 -C5orf46 MGC23985, SSSP1 ENSG00000178776 Chromosome 5 open reading frame 46 5 147880726-147906538 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA058999 Approved Nuclear speckles
Mitochondria Group enriched 9 breast: 17.4;salivary gland: 77.8;skin: 62.3;testis: 19.7 heart muscle: 4.9 -CD300LB CLM7, TREM5 ENSG00000178789 CD300 molecule-like family member b 17 74521174-74531474 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 appendix: 11.7 spleen: 5.3 -GDPD4 GDE6 ENSG00000178795 Glycerophosphodiester phosphodiesterase domain containing 4 11 77216558-77301687 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 7 testis: 4.8 placenta: 0.6 -RIIAD1 C1orf230, FLJ36032, NCRNA00166 ENSG00000178796 Regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 1 151710433-151729805 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA045703 Supported Approved Nucleoplasm
Cytosol Group enriched 8 fallopian tube: 69.8;testis: 22.4 cerebral cortex: 5.4 -MPI ENSG00000178802 Mannose phosphate isomerase 15 74890005-74902219 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007200 Approved Approved Plasma membrane
Cytosol Expressed in all parathyroid gland: 51.1 -H1FOO ENSG00000178804 H1 histone family, member O, oocyte-specific 3 129543214-129551467 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037992 Uncertain Tissue enriched 59 testis: 5.8 epididymis: 0.0 -TRIM73 TRIM50B ENSG00000178809 Tripartite motif containing 73 7 75395063-75410996 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047843, HPA051845 Uncertain Uncertain Cytosol Mixed stomach: 8.6 -OPLAH 5-Opase, OPLA ENSG00000178814 5-oxoprolinase (ATP-hydrolysing) 8 144051266-144063832 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026562, HPA028260, HPA052429 Uncertain Approved Nucleoli fibrillar center Tissue enhanced 0 testis: 65.6 duodenum: 15.9 -TMEM52 ENSG00000178821 Transmembrane protein 52 1 1917590-1919273 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 pancreas: 38.8;skeletal muscle: 105.7 adrenal gland: 24.5 -TMEM139 FLJ90586 ENSG00000178826 Transmembrane protein 139 7 143279957-143288048 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA036982, HPA036983 Approved Approved Plasma membrane
Focal adhesion sites Tissue enhanced 0 duodenum: 34.9;kidney: 34.4 small intestine: 21.2 -RNF186 FLJ20225 ENSG00000178828 Ring finger protein 186 1 19814029-19815278 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA034547, HPA035558 Supported Tissue enhanced 0 duodenum: 136.0;epididymis: 82.8;small intestine: 47.7 kidney: 26.4 -EFCAB13 C17orf57, FLJ40342 ENSG00000178852 EF-hand calcium binding domain 13 17 47323290-47441312 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB002501, HPA021633, HPA023249, HPA026561 Uncertain Tissue enhanced 0 testis: 40.7 thyroid gland: 23.6 -MSC ABF-1, bHLHa22 ENSG00000178860 Musculin 8 71841549-71844468 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA062878 Supported Nucleoplasm Mixed placenta: 22.6 -APOLD1 DKFZP434F0318, FLJ25138 ENSG00000178878 Apolipoprotein L domain containing 1 12 12725917-12829975 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA052462, HPA058882 Approved Validated Nucleoplasm
Cytosol Tissue enhanced 0 adipose tissue: 142.0 placenta: 121.8 -FAM101A FLJ44614 ENSG00000178882 Family with sequence similarity 101, member A 12 123973241-124316024 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058911 Approved Nucleoplasm Tissue enriched 5 stomach: 92.1 small intestine: 17.1 -EXOSC4 FLJ20591, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p ENSG00000178896 Exosome component 4 8 144078626-144080647 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024792 Approved Supported Intermediate filaments
Cytosol Expressed in all testis: 56.3 -DPY19L3 ENSG00000178904 Dpy-19-like 3 (C. elegans) 19 32405543-32485895 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008325 Approved Approved Microtubules Mixed cerebral cortex: 20.4 -TAF7 TAF2F, TAFII55 ENSG00000178913 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 5 141260225-141320821 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006429 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all testis: 138.1 -ZNF852 ENSG00000178917 Zinc finger protein 852 3 44498970-44510640 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA048312, HPA049885, HPA071850 Uncertain Mixed parathyroid gland: 2.5 -FOXE1 FKHL15, FOXE2, HFKH4, TITF2, TTF-2 ENSG00000178919 Forkhead box E1 9 97853254-97856715 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 14 thyroid gland: 326.9 tonsil: 22.9 -PFAS FGARAT, KIAA0361, PURL ENSG00000178921 Phosphoribosylformylglycinamidine synthase 17 8247618-8270491 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022140, HPA022886 Supported Approved Nucleoplasm
Plasma membrane Expressed in all lymph node: 11.8 -HYI HT036 ENSG00000178922 Hydroxypyruvate isomerase (putative) 1 43451003-43453989 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040092 Uncertain Approved Golgi apparatus
Plasma membrane
Cytosol Expressed in all seminal vesicle: 80.3 -C17orf62 FLJ90469, MGC4368 ENSG00000178927 Chromosome 17 open reading frame 62 17 82442589-82450829 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045696 Uncertain Approved Plasma membrane
Cell Junctions Expressed in all lymph node: 129.5 -TPRX1 FLJ40321 ENSG00000178928 Tetra-peptide repeat homeobox 1 19 47801243-47819051 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044922 Uncertain Tissue enriched 13 testis: 1.3 adipose tissue: 0.0 -LGALS7B GAL7 ENSG00000178934 Lectin, galactoside-binding, soluble, 7B 19 38789211-38791749 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA001549, CAB025100 Supported Tissue enhanced 0 breast: 10.2;esophagus: 19.4 skeletal muscle: 3.8 -ZNF552 FLJ21603 ENSG00000178935 Zinc finger protein 552 19 57803841-57814913 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043800, HPA053762, HPA072145 Uncertain Uncertain Nucleus Mixed breast: 34.7 -SMIM10L2A LED, LINC00086, MGC39606, NCRNA00086 ENSG00000178947 Small integral membrane protein 10 like 2A X 135421943-135428074 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 adrenal gland: 21.9;cerebral cortex: 22.6 epididymis: 17.4 -GAK DNAJC26 ENSG00000178950 Cyclin G associated kinase 4 849276-932373 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027405, HPA027459, HPA027463 Approved Validated Golgi apparatus
Vesicles Expressed in all duodenum: 52.9 -ZBTB7A DKFZp547O146, FBI-1, LRF, pokemon, ZBTB7, ZNF857A ENSG00000178951 Zinc finger and BTB domain containing 7A 19 4044364-4066945 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037214, CAB037285, HPA046387 Supported Approved Nucleoplasm Expressed in all cerebral cortex: 23.9 -TUFM EF-TuMT, EFTu ENSG00000178952 Tu translation elongation factor, mitochondrial 16 28842411-28846408 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018991, HPA024087, CAB075730, CAB075731 Supported Validated Mitochondria Expressed in all parathyroid gland: 160.0 -ERICH3 C1orf173, DKFZp547I048, RP11-653A5.1 ENSG00000178965 Glutamate-rich 3 1 74568111-74673738 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA028655 Approved Tissue enhanced 0 cerebral cortex: 18.9;fallopian tube: 27.5;testis: 44.0 cervix: 8.6 -RMI1 BLAP75, C9orf76, FLJ12888 ENSG00000178966 RecQ mediated genome instability 1 9 83980711-84004074 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021661 Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 21.0 -CTC1 AAF132, C17orf68, FLJ22170 ENSG00000178971 CTS telomere maintenance complex component 1 17 8224821-8248044 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all spleen: 31.5 -FBXO34 Fbx34, FLJ20725 ENSG00000178974 F-box protein 34 14 55271303-55361918 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052592 Uncertain Approved Nuclear speckles Expressed in all testis: 46.9 -SEPW1 selW ENSG00000178980 Selenoprotein W, 1 19 47778572-47784686 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 442.1 -EIF3K ARG134, eIF3k, EIF3S12, HSPC029, M9, PLAC-24, PRO1474, PTD001 ENSG00000178982 Eukaryotic translation initiation factor 3, subunit K 19 38619082-38636955 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045446, HPA054590 Uncertain Supported Cytosol Expressed in all fallopian tube: 162.8 -MRFAP1L1 MGC9651 ENSG00000178988 Morf4 family associated protein 1-like 1 4 6707701-6709880 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all cerebral cortex: 91.5 -SNX18 SH3PX2, SH3PXD3B, SNAG1 ENSG00000178996 Sorting nexin 18 5 54517759-54546585 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037800 Approved Approved Cytosol Expressed in all bone marrow: 42.9 -EXD1 EXDL1, MGC33637 ENSG00000178997 Exonuclease 3'-5' domain containing 1 15 41182725-41230743 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 72 testis: 28.8 epididymis: 0.4 -AURKB Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5 ENSG00000178999 Aurora kinase B 17 8204733-8210600 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005862, HPA037708 Supported Supported Nucleoplasm
Midbody Tissue enhanced 0 lymph node: 45.0;tonsil: 35.2 bone marrow: 28.2 -TAS1R2 GPR71, T1R2, TR2 ENSG00000179002 Taste receptor, type 1, member 2 1 18839599-18859682 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level No evidence No evidence Evidence at protein level Not detected epididymis: 0.0 -C14orf39 SIX6OS1 ENSG00000179008 Chromosome 14 open reading frame 39 14 60396469-60515543 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059518 Uncertain Approved Nucleus
Nucleoli Tissue enriched 8 testis: 19.6 adrenal gland: 2.4 -MRFAP1 PAM14, PGR1 ENSG00000179010 Morf4 family associated protein 1 4 6640091-6642745 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB042447, HPA056367 Approved Approved Nucleus Expressed in all cerebral cortex: 506.5 -C3orf38 MGC26717 ENSG00000179021 Chromosome 3 open reading frame 38 3 88149743-88168729 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034736, HPA034737 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 58.7 -KLHDC7A FLJ38753 ENSG00000179023 Kelch domain containing 7A 1 18480982-18486126 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056616 Uncertain Approved Nuclear speckles Tissue enhanced 0 kidney: 20.7 urinary bladder: 6.6 -TMEM107 MGC10744 ENSG00000179029 Transmembrane protein 107 17 8173237-8176399 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052555, HPA059653 Approved Approved Nucleoplasm
Midbody
Midbody ring
Cytosol Mixed fallopian tube: 71.3 -RRS1 KIAA0112 ENSG00000179041 Ribosome biogenesis regulator homolog 8 66429028-66430733 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055549, HPA060937 Approved Validated Nucleoli Expressed in all appendix: 16.8 -EXOC3L1 EXOC3L, FLJ35539, FLJ35587 ENSG00000179044 Exocyst complex component 3-like 1 16 67184366-67190204 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029574 Uncertain Approved Vesicles
Plasma membrane Tissue enhanced 0 spleen: 30.6 placenta: 8.4 -TRIML2 FLJ25801, SPRYD6 ENSG00000179046 Tripartite motif family-like 2 4 188091273-188109603 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043838 Uncertain Approved Plasma membrane
Cytosol Group enriched 25 placenta: 5.9;testis: 3.4 cerebral cortex: 0.1 -RCC2 TD-60 ENSG00000179051 Regulator of chromosome condensation 2 1 17406760-17439724 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072281 Approved Mixed skin: 35.4 -OR13D1 ENSG00000179055 Olfactory receptor, family 13, subfamily D, member 1 9 104694422-104695462 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA055921 Uncertain Not detected testis: 0.5 -IGSF22 FLJ37794, IGFN2 ENSG00000179057 Immunoglobulin superfamily, member 22 11 18704305-18726230 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB026459 Uncertain Tissue enhanced 0 skin: 1.2;testis: 1.0 cerebral cortex: 0.8 -C9orf50 FLJ35803 ENSG00000179058 Chromosome 9 open reading frame 50 9 129612225-129620776 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA026743 Supported Tissue enhanced 0 testis: 8.1 cerebral cortex: 1.8 -ZFP42 REX1, ZNF754 ENSG00000179059 ZFP42 zinc finger protein 4 187995771-188005050 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level CAB025557 Uncertain Tissue enhanced 0 testis: 3.5 skin: 1.2 -CCDC89 FLJ38159 ENSG00000179071 Coiled-coil domain containing 89 11 85684866-85686277 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039351, HPA040628 Uncertain Approved Nucleoplasm Tissue enhanced 0 fallopian tube: 19.1;testis: 53.2 ovary: 8.1 -FAM133A CT115, FLJ37659, RP1-32F7.2 ENSG00000179083 Family with sequence similarity 133, member A X 93674013-93712274 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA066175, HPA069513 Approved Nucleus
Nucleoli Group enriched 6 cerebral cortex: 5.3;testis: 14.0 adrenal gland: 1.5 -DPM3 MGC125904, MGC125905, MGC34275 ENSG00000179085 Dolichyl-phosphate mannosyltransferase polypeptide 3 1 155139891-155140595 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014667 Approved Expressed in all adrenal gland: 78.8 -C12orf42 FLJ25323 ENSG00000179088 Chromosome 12 open reading frame 42 12 103237591-103496010 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 16 testis: 25.1 spleen: 1.5 -CYC1 UQCR4 ENSG00000179091 Cytochrome c-1 8 144095027-144097525 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001247 Supported Supported Mitochondria Expressed in all skeletal muscle: 242.3 -PER1 PER, RIGUI ENSG00000179094 Period circadian clock 1 17 8140472-8156506 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047947, HPA067064 Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 70.1 -HTR1F 5-HT1F, HTR1EL ENSG00000179097 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 3 87990696-87993835 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA005555 Uncertain Tissue enhanced 0 placenta: 2.7 cerebral cortex: 1.0 -TMTC2 DKFZp762A217 ENSG00000179104 Transmembrane and tetratricopeptide repeat containing 2 12 82686880-83134870 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA026954, HPA026955 Uncertain Approved Actin filaments
Cytosol Mixed cerebral cortex: 16.4 -HES7 bHLHb37 ENSG00000179111 Hes family bHLH transcription factor 7 17 8120590-8124092 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA072105 Uncertain Approved Nucleoplasm
Nucleoli Tissue enhanced 0 placenta: 1.1 testis: 1.0 -FARSA CML33, FARSL, FARSLA ENSG00000179115 Phenylalanyl-tRNA synthetase, alpha subunit 19 12922479-12934037 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001911 Approved Supported Cytosol Expressed in all cerebral cortex: 67.4 -SPTY2D1 DKFZp686I068, FLJ39441, Spt2 ENSG00000179119 SPT2 chromatin protein domain containing 1 11 18606401-18634791 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039372, HPA047957 Approved Approved Nucleus
Nucleoli Expressed in all bone marrow: 21.4 -C10orf67 MGC46732 ENSG00000179133 Chromosome 10 open reading frame 67 10 23267195-23344845 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA038130, HPA038131 Approved Approved Nucleoplasm
Nucleoli Tissue enhanced 0 fallopian tube: 9.3;testis: 30.5 lung: 5.1 -SAMD4B FLJ10211, hSmaug2, MGC99832, SMGB ENSG00000179134 Sterile alpha motif domain containing 4B 19 39342396-39385710 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016800, HPA059385 Approved Validated Cytosol Expressed in all parathyroid gland: 67.0 -CYP11B2 ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo ENSG00000179142 Cytochrome P450, family 11, subfamily B, polypeptide 2 8 142910559-142917843 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049171, HPA056348, HPA057752 Supported Tissue enriched 899 adrenal gland: 126.7 testis: 0.1 -GIMAP7 IAN7, MGC27027 ENSG00000179144 GTPase, IMAP family member 7 7 150514830-150521073 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020266, HPA020268 Supported Approved Vesicles
Cytosol Expressed in all lymph node: 184.0 -ALOXE3 E-LOX, eLOX3 ENSG00000179148 Arachidonate lipoxygenase 3 17 8095900-8119047 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023120 Approved Plasma membrane
Cytosol Tissue enriched 17 skin: 36.6 breast: 2.2 -EDC3 FLJ21128, hYjeF_N2-15q23, LSM16, YJDC, YJEFN2 ENSG00000179151 Enhancer of mRNA decapping 3 15 74630558-74696292 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040650, HPA044206, HPA066137 Uncertain Supported Cytoplasmic bodies Expressed in all testis: 65.8 -TCAIM C3orf23, DKFZp313N0621, TOAG-1 ENSG00000179152 T cell activation inhibitor, mitochondrial 3 44338119-44409451 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all parathyroid gland: 22.6 -FUCA1 ENSG00000179163 Fucosidase, alpha-L- 1, tissue 1 23845077-23868294 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046542, HPA056371 Supported Expressed in all lymph node: 188.2 -PXT1 STEPP ENSG00000179165 Peroxisomal, testis specific 1 6 36390551-36442889 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044042 Uncertain Tissue enriched 7 testis: 3.6 appendix: 0.5 -GGN FLJ35713, MGC33369 ENSG00000179168 Gametogenetin 19 38384265-38388082 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 11 testis: 35.0 small intestine: 3.2 -HNRNPCL1 HNRPCL1 ENSG00000179172 Heterogeneous nuclear ribonucleoprotein C-like 1 1 12847377-12947578 Predicted intracellular proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected testis: 0.1 -TMEM125 MGC17299 ENSG00000179178 Transmembrane protein 125 1 43269994-43274002 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015796 Approved Midbody
Cytosol Tissue enhanced 0 lung: 113.9 thyroid gland: 51.5 -ZNF664 DKFZp761B128, ZFOC1, ZNF176 ENSG00000179195 Zinc finger protein 664 12 123971845-124015439 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047846 Approved Nucleoplasm Expressed in all parathyroid gland: 231.9 -SIGLECL1 C19orf75, FLJ40235, SIGLEC23P, SIGLECP7 ENSG00000179213 SIGLEC family like 1 19 51246348-51269330 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 81 testis: 40.0 cervix: 0.4 -CALR cC1qR, CRT, FLJ26680, RO, SSA ENSG00000179218 Calreticulin 19 12938578-12944489 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001513, HPA002242, CAB019952 Supported Expressed in all thyroid gland: 1647.1 -MAGED1 DLXIN-1, NRAGE ENSG00000179222 Melanoma antigen family D1 X 51803007-51902357 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043645 Approved Cytosol Expressed in all cerebral cortex: 194.4 -RP11-111M22.2 ENSG00000179240 11 76381313-76414619 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA057405 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Centrosome Mixed testis: 8.4 -LDLRAD3 LRAD3 ENSG00000179241 Low density lipoprotein receptor class A domain containing 3 11 35943981-36232136 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA038251 Approved Supported Cell Junctions Mixed breast: 22.9 -CDH4 ENSG00000179242 Cadherin 4, type 1, R-cadherin (retinal) 20 61252426-61940617 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA015613 Validated Plasma membrane Tissue enhanced 0 cerebral cortex: 6.0;spleen: 4.9 seminal vesicle: 1.3 -SMCO3 C12orf69, LOC440087 ENSG00000179256 Single-pass membrane protein with coiled-coil domains 3 12 14804650-14814182 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040574, HPA047804 Uncertain Tissue enhanced 0 cervix, uterine: 5.6 gallbladder: 3.0 -RAD23A HHR23A, MGC111083 ENSG00000179262 RAD23 homolog A, nucleotide excision repair protein 19 12945855-12953642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053901, HPA057003, HPA065599 Supported Supported Nucleoplasm
Cytosol Expressed in all skeletal muscle: 334.2 -C2orf71 FLJ34931, RP54 ENSG00000179270 Chromosome 2 open reading frame 71 2 29060976-29074261 Disease related genes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level HPA051819 Uncertain Not detected heart muscle: 0.4 -GADD45GIP1 CKBBP2, CKbetaBP2, CRIF1, MGC4667, MGC4758, PLINP-1, Plinp1, PRG6 ENSG00000179271 Growth arrest and DNA-damage-inducible, gamma interacting protein 1 19 12953119-12957236 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055205, HPA065048 Supported Supported Mitochondria Expressed in all cerebral cortex: 29.7 -DAND5 CER2, CKTSF1B3, DANTE, DTE, FLJ38607, GREM3 ENSG00000179284 DAN domain family member 5, BMP antagonist 19 12965159-12974762 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049472 Uncertain Tissue enhanced 0 heart muscle: 5.3 bone marrow: 1.3 -TMEM151A MGC33486, TMEM151 ENSG00000179292 Transmembrane protein 151A 11 66291870-66296664 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041035 Uncertain Approved Nucleoli
Cytosol Tissue enriched 24 cerebral cortex: 45.4 adrenal gland: 1.8 -PTPN11 BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2 ENSG00000179295 Protein tyrosine phosphatase, non-receptor type 11 12 112418351-112509913 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005377 Approved Supported Nucleus
Nucleoli
Actin filaments
Cytosol Expressed in all cerebral cortex: 124.6 -NSUN7 FLJ14001 ENSG00000179299 NOP2/Sun domain family, member 7 4 40749897-40809985 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA020653 Uncertain Supported Vesicles Tissue enhanced 0 testis: 31.4 fallopian tube: 11.4 -ZCCHC5 FLJ38865, Mar3, Mart3, ZHC5 ENSG00000179300 Zinc finger, CCHC domain containing 5 X 78656069-78659328 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051991, HPA053174, HPA075136 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Not detected smooth muscle: 0.7 -FAM156B TMEM29B ENSG00000179304 Family with sequence similarity 156, member B X 52891306-52908560 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA056640, HPA056643 Uncertain Tissue enhanced 0 placenta: 46.3 skin: 24.9 -WSCD1 KIAA0523 ENSG00000179314 WSC domain containing 1 17 5772234-6124427 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015919 Uncertain Approved Nucleoplasm
Golgi apparatus Tissue enhanced 0 cerebral cortex: 30.4;spleen: 19.2 testis: 15.3 -RAB39A RAB39 ENSG00000179331 RAB39A, member RAS oncogene family 11 107928503-107963482 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042505 Uncertain Tissue enhanced 0 cerebral cortex: 7.0 spleen: 4.3 -CLK3 clk3 ENSG00000179335 CDC-like kinase 3 15 74598500-74645414 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046817 Approved Supported Nucleoplasm
Intermediate filaments Expressed in all bone marrow: 71.9 -HLA-DQB1 CELIAC1, HLA-DQB, IDDM1 ENSG00000179344 Major histocompatibility complex, class II, DQ beta 1 6 32659467-32668383 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA013667 Uncertain Approved Golgi apparatus Tissue enhanced 0 lymph node: 292.8 lung: 269.6 -GATA2 NFE1B ENSG00000179348 GATA binding protein 2 3 128479427-128493185 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA005633, CAB024847 Approved Supported Nucleoplasm Tissue enhanced 0 seminal vesicle: 76.1 prostate: 60.0 -ARID3B BDP, DRIL2 ENSG00000179361 AT rich interactive domain 3B (BRIGHT-like) 15 74541177-74598131 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050320 Approved Supported Nucleoplasm Tissue enhanced 0 testis: 36.7 placenta: 22.1 -TMEM31 MGC39655 ENSG00000179363 Transmembrane protein 31 X 103710909-103714028 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052760 Approved Nucleoli fibrillar center Tissue enriched 61 testis: 84.9 placenta: 1.3 -PACS2 KIAA0602, PACS1L ENSG00000179364 Phosphofurin acidic cluster sorting protein 2 14 105300563-105398147 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001423, HPA077892 Approved Approved Mitochondria Expressed in all cerebral cortex: 63.4 -ELMOD2 MGC10084 ENSG00000179387 ELMO/CED-12 domain containing 2 4 140524158-140553770 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047600 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all thyroid gland: 28.0 -EGR3 PILOT ENSG00000179388 Early growth response 3 8 22687659-22693302 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA006206, CAB009373 Uncertain Uncertain Nucleus
Vesicles Mixed gallbladder: 49.7 -C1orf101 MGC33370 ENSG00000179397 Chromosome 1 open reading frame 101 1 244454377-244641177 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 12 testis: 38.3 epididymis: 3.1 -GPC5 ENSG00000179399 Glypican 5 13 91398607-92873682 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040152, HPA044081 Supported Approved Nucleus
Cytosol Tissue enhanced 0 cerebral cortex: 15.9;kidney: 8.1;testis: 11.5 lung: 4.9 -VWA1 FLJ22215, VWA-1, WARP ENSG00000179403 Von Willebrand factor A domain containing 1 1 1434861-1442882 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 seminal vesicle: 291.3 prostate: 111.2 -DNAJB8 CT156, MGC33884 ENSG00000179407 DnaJ (Hsp40) homolog, subfamily B, member 8 3 128462439-128467248 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 314 testis: 31.3 epididymis: 0.0 -GEMIN4 DKFZP434B131, DKFZP434D174, HC56, HCAP1, HHRF-1, p97 ENSG00000179409 Gem (nuclear organelle) associated protein 4 17 744414-753999 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065699, HPA067891 Uncertain Supported Nuclear bodies
Cytosol Expressed in all testis: 78.4 -HNRNPCL4 ENSG00000179412 Heterogeneous nuclear ribonucleoprotein C-like 4 1 13164586-13165467 Predicted intracellular proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -FJX1 FLJ22416, FLJ25593 ENSG00000179431 Four jointed box 1 11 35618419-35620868 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059220 Uncertain Approved Vesicles Tissue enhanced 0 cerebral cortex: 22.4 endometrium: 8.8 -KLHL28 BTBD5, FLJ20081 ENSG00000179454 Kelch-like family member 28 14 44924319-45042322 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000988 Approved Cytosol Mixed bone marrow: 17.2 -MKRN3 D15S9, MGC88288, RNF63, ZFP127, ZNF127 ENSG00000179455 Makorin ring finger protein 3 15 23565678-23630075 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029494 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 5.9;placenta: 4.1;testis: 3.7 epididymis: 1.1 -ZBTB18 C2H2-171, RP58, TAZ-1, ZNF238 ENSG00000179456 Zinc finger and BTB domain containing 18 1 244048939-244057476 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044652 Supported Nucleoplasm
Microtubules
Cytokinetic bridge Expressed in all cerebral cortex: 76.5 -OR9A2 ENSG00000179468 Olfactory receptor, family 9, subfamily A, member 2 7 143026158-143027195 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -C14orf28 DRIP-1 ENSG00000179476 Chromosome 14 open reading frame 28 14 44897295-44907257 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059635 Approved Cytosol Mixed testis: 15.5 -ALOX12B 12R-LOX ENSG00000179477 Arachidonate 12-lipoxygenase, 12R type 17 8072636-8087703 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024002 Supported Approved Cytosol Group enriched 7 skin: 70.1;tonsil: 18.1 esophagus: 6.2 -SLC17A8 DFNA25, VGLUT3 ENSG00000179520 Solute carrier family 17 (vesicular glutamate transporter), member 8 12 100357079-100422059 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 small intestine: 5.9 cerebral cortex: 1.3 -SHARPIN DKFZP434N1923, SIPL1 ENSG00000179526 SHANK-associated RH domain interactor 8 144098633-144108124 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044453 Approved Supported Nucleus
Cytosol Expressed in all testis: 66.1 -LBX2 ENSG00000179528 Ladybird homeobox 2 2 74497517-74503316 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044257 Uncertain Approved Nucleus
Midbody Tissue enhanced 0 duodenum: 5.5;small intestine: 5.4 liver: 3.5 -DNHD1 C11orf47, CCDC35, DHCD1, DKFZp686J0796, DNHD1L, FLJ32752, FLJ35709, FLJ46184 ENSG00000179532 Dynein heavy chain domain 1 11 6497260-6593758 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039698, HPA040267, HPA057639 Uncertain Approved Nucleoplasm
Cytokinetic bridge Tissue enriched 6 testis: 19.5 bone marrow: 3.5 -SLITRK4 DKFZp547M2010 ENSG00000179542 SLIT and NTRK-like family, member 4 X 143622790-143635777 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000431 Approved Uncertain Microtubules Tissue enhanced 0 adrenal gland: 14.0;cerebral cortex: 12.8 cervix: 8.3 -HTR1D 5-HT1D, HT1DA, HTRL, RDC4 ENSG00000179546 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 1 23191895-23194729 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 8 duodenum: 9.7;gallbladder: 2.5;small intestine: 9.3 fallopian tube: 0.8 -GCC1 FLJ22035, GCC1P, GCC88, MGC20706 ENSG00000179562 GRIP and coiled-coil domain containing 1 7 127580618-127593611 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019369, HPA021323 Supported Validated Golgi apparatus
Plasma membrane
Cytosol Expressed in all testis: 18.7 -LSMEM2 C3orf45, FLJ38608 ENSG00000179564 Leucine-rich single-pass membrane protein 2 3 50279027-50288114 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 6 heart muscle: 14.2;skeletal muscle: 5.4;testis: 2.9 cervix: 1.2 -RNF151 ENSG00000179580 Ring finger protein 151 16 1966823-1968975 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 431 testis: 73.1 skin: 0.1 -CIITA C2TA, MHC2TA, NLRA ENSG00000179583 Class II, major histocompatibility complex, transactivator 16 10877198-10932281 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB016084 Approved Approved Nucleoplasm Mixed spleen: 53.8 -ZFPM1 FOG, FOG1, ZC2HC11A, ZNF89A ENSG00000179588 Zinc finger protein, FOG family member 1 16 88453317-88537016 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046603 Supported Approved Nucleoplasm
Cytosol Mixed stomach: 13.9 -ALOX15B 15-LOX-2 ENSG00000179593 Arachidonate 15-lipoxygenase, type B 17 8039017-8049134 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010562 Approved Cytosol Group enriched 5 breast: 142.3;prostate: 122.6 lung: 26.1 -PLD6 ENSG00000179598 Phospholipase D family, member 6 17 17200995-17206315 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049345 Approved Tissue enhanced 0 testis: 29.2 ovary: 8.9 -GPHB5 GPB5, ZLUT1 ENSG00000179600 Glycoprotein hormone beta 5 14 63312835-63318879 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.2 -GRM8 GLUR8, GPRC1H, mGlu8, MGLUR8 ENSG00000179603 Glutamate receptor, metabotropic 8 7 126438598-127253294 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051481 Uncertain Tissue enhanced 0 cerebral cortex: 4.1 testis: 2.9 -CDC42EP4 BORG4, CEP4, KAIA1777, MGC17125, MGC3740 ENSG00000179604 CDC42 effector protein (Rho GTPase binding) 4 17 73283624-73312175 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023335, HPA024797 Approved Supported Validated Plasma membrane
Actin filaments
Microtubules Expressed in all cerebral cortex: 102.1 -OR2AP1 OR2AP1P ENSG00000179615 Olfactory receptor, family 2, subfamily AP, member 1 12 55574415-55575344 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -OR6C4 ENSG00000179626 Olfactory receptor, family 6, subfamily C, member 4 12 55551199-55552244 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -ZBTB42 ZNF925 ENSG00000179627 Zinc finger and BTB domain containing 42 14 104800596-104804712 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA000703, HPA066961 Uncertain Supported Nucleus Mixed prostate: 8.0 -LACC1 C13orf31, FLJ38725 ENSG00000179630 Laccase (multicopper oxidoreductase) domain containing 1 13 43879284-43893932 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB034228, HPA040150, HPA044211 Uncertain Approved Nucleoplasm
Cytokinetic bridge
Cytosol Mixed testis: 17.1 -MAF1 DKFZp586G1123 ENSG00000179632 MAF1 homolog, negative regulator of RNA polymerase III 8 144104499-144107611 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024821, HPA058548 Uncertain Supported Nucleus
Nucleoli
Vesicles Expressed in all skeletal muscle: 142.6 -TPPP2 C14orf8, CT152, p18, p25beta ENSG00000179636 Tubulin polymerization-promoting protein family member 2 14 21024109-21036276 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004120 Supported Tissue enriched 46 testis: 307.1 liver: 6.7 -FCER1A FCE1A ENSG00000179639 Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1 159289714-159308224 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB022102, HPA036051, CAB055526 Approved Mixed skin: 39.9 -RPRML MGC43894 ENSG00000179673 Reprimo-like 17 46978156-46979248 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062668 Uncertain Tissue enriched 11 cerebral cortex: 8.4 epididymis: 0.7 -ARL14 ARF7, FLJ22595 ENSG00000179674 ADP-ribosylation factor-like 14 3 160677159-160678452 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 gallbladder: 209.4;stomach: 70.4 duodenum: 52.4 -OR6C2 OR6C67 ENSG00000179695 Olfactory receptor, family 6, subfamily C, member 2 12 55452214-55453152 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.3 -WDR97 KIAA1875 ENSG00000179698 WD repeat domain 97 8 144107726-144118315 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059409 Uncertain Tissue enriched 9 testis: 1.2 skin: 0.1 -NLRP8 CLR19.2, NALP8, NOD16, PAN4 ENSG00000179709 NLR family, pyrin domain containing 8 19 55947832-55988629 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA056989 Uncertain Not detected breast: 0.5 -PCED1B FAM113B, MGC16044 ENSG00000179715 PC-esterase domain containing 1B 12 47079603-47236662 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043901 Approved Approved Golgi apparatus
Vesicles Mixed lymph node: 42.9 -APOBEC3B FLJ21201, PHRBNL ENSG00000179750 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 22 38982347-38992804 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056980, HPA066719 Approved Nucleoplasm Tissue enhanced 0 bone marrow: 18.9 rectum: 14.2 -SYCN FLJ27441, INSSA1, SYL ENSG00000179751 Syncollin 19 39202831-39204266 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047654 Supported Tissue enriched 400 pancreas: 6058.1 ovary: 15.1 -PIPOX LPIPOX ENSG00000179761 Pipecolic acid oxidase 17 28950513-29057220 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 7 kidney: 136.7;liver: 235.2 epididymis: 26.2 -FOXS1 FKHL18, FREAC10 ENSG00000179772 Forkhead box S1 20 31844301-31845619 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA042475 Approved Approved Nucleoplasm
Cytosol Mixed placenta: 7.0 -ATOH7 bHLHa13, Math5 ENSG00000179774 Atonal bHLH transcription factor 7 10 68230624-68232103 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA027008 Uncertain Tissue enriched 6 cerebral cortex: 2.2 small intestine: 0.3 -CDH5 7B4, CD144 ENSG00000179776 Cadherin 5, type 2 (vascular endothelium) 16 66366622-66404786 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB028366 Approved Tissue enhanced 0 placenta: 332.2 lung: 120.6 -LRRC3B LRP15 ENSG00000179796 Leucine rich repeat containing 3B 3 26622806-26710776 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015568 Approved Group enriched 7 cerebral cortex: 19.2;skeletal muscle: 3.9;testis: 13.0 ovary: 1.6 -FAM216B C13orf30, FLJ40919 ENSG00000179813 Family with sequence similarity 216, member B 13 42781550-42791549 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040118 Uncertain Tissue enriched 8 fallopian tube: 121.7 lung: 15.2 -MRGPRX4 MRGX4 ENSG00000179817 MAS-related GPR, member X4 11 18172837-18197348 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected testis: 0.1 -MYADM ENSG00000179820 Myeloid-associated differentiation marker 19 53866223-53876437 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056301 Approved Nuclear speckles Expressed in all smooth muscle: 257.6 -MRGPRX3 MRGX3 ENSG00000179826 MAS-related GPR, member X3 11 18120955-18138480 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 salivary gland: 1.3 testis: 0.9 -MROH1 HEATR7A, KIAA1833 ENSG00000179832 Maestro heat-like repeat family member 1 8 144148016-144261940 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044465 Approved Expressed in all thyroid gland: 14.9 -SERTAD2 KIAA0127, Sei-2, TRIP-Br2 ENSG00000179833 SERTA domain containing 2 2 64631621-64751005 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA019021, HPA020904 Supported Supported Nucleoplasm
Cytosol Expressed in all bone marrow: 54.0 -AKAP5 AKAP75, AKAP79 ENSG00000179841 A kinase (PRKA) anchor protein 5 14 64465499-64474503 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004308, HPA053891 Supported Approved Nucleoplasm Tissue enriched 5 cerebral cortex: 22.6 rectum: 4.4 -NKPD1 FLJ33600 ENSG00000179846 NTPase, KAP family P-loop domain containing 1 19 45149750-45160150 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043339 Uncertain Tissue enriched 18 skin: 13.9 seminal vesicle: 0.7 -GIPC3 C19orf64, DFNB15, DFNB72, DFNB95 ENSG00000179855 GIPC PDZ domain containing family, member 3 19 3585553-3593541 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061258, HPA067765 Approved Approved Nucleoplasm
Nuclear bodies
Golgi apparatus Mixed smooth muscle: 11.4 -CITED4 ENSG00000179862 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 1 40861051-40862366 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA056434 Approved Approved Vesicles Mixed breast: 20.5 -ABCA13 FLJ33876, FLJ33951 ENSG00000179869 ATP-binding cassette, sub-family A (ABC1), member 13 7 48171458-48647496 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA063601 Approved Vesicles
Centrosome
Cytosol Tissue enriched 10 bone marrow: 29.4 testis: 3.0 -NLRP11 CLR19.6, NALP11, NOD17, PAN10, PYPAF6 ENSG00000179873 NLR family, pyrin domain containing 11 19 55785397-55836800 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046402 Uncertain Tissue enhanced 0 epididymis: 1.2;testis: 1.3 tonsil: 0.4 -TIGD5 FLJ14926 ENSG00000179886 Tigger transposable element derived 5 8 143597835-143603224 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed parathyroid gland: 2.2 -PDXDC1 KIAA0251 ENSG00000179889 Pyridoxal-dependent decarboxylase domain containing 1 16 14974591-15139339 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047369, HPA049121, HPA051484 Approved Validated Golgi apparatus
Vesicles Expressed in all testis: 105.9 -C1orf194 ENSG00000179902 Chromosome 1 open reading frame 194 1 109105951-109113857 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA031144, HPA049684 Supported Uncertain Nuclear speckles
Cytosol Group enriched 30 fallopian tube: 195.3;testis: 197.5 lung: 6.5 -ZNF154 pHZ-92 ENSG00000179909 Zinc finger protein 154 19 57697367-57709194 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed parathyroid gland: 9.6 -R3HDM2 KIAA1002 ENSG00000179912 R3H domain containing 2 12 57253762-57431005 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038327, HPA038328 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 51.9 -B3GNT3 B3GN-T3, B3GNT-3, beta3Gn-T3, HP10328, TMEM3 ENSG00000179913 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 19 17794828-17813082 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024298 Approved Tissue enhanced 0 rectum: 51.7 colon: 49.7 -ITLN1 FLJ20022, hIntL, HL-1, ITLN, LFR ENSG00000179914 Intelectin 1 (galactofuranose binding) 1 160876539-160885170 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012652, HPA063275 Approved Tissue enhanced 0 colon: 458.1;rectum: 1445.3;small intestine: 477.9 duodenum: 284.1 -NRXN1 Hs.22998, KIAA0578 ENSG00000179915 Neurexin 1 2 49918505-51225564 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 cerebral cortex: 83.7 testis: 12.1 -SEPHS2 SPS2, SPS2b ENSG00000179918 Selenophosphate synthetase 2 16 30444381-30446181 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA047931 Approved Approved Nucleoplasm Expressed in all liver: 164.0 -OR10A7 ENSG00000179919 Olfactory receptor, family 10, subfamily A, member 7 12 55221025-55221975 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA055111 Uncertain Not detected epididymis: 0.0 -GPBAR1 BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5 ENSG00000179921 G protein-coupled bile acid receptor 1 2 218259496-218263859 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062890 Approved Tissue enhanced 0 gallbladder: 27.0;smooth muscle: 13.8 adipose tissue: 10.0 -ZNF784 MGC75238 ENSG00000179922 Zinc finger protein 784 19 55620742-55624601 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059676 Uncertain Approved Nucleus Expressed in all skeletal muscle: 14.7 -ZNF648 FLJ46813 ENSG00000179930 Zinc finger protein 648 1 182054570-182061712 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053897 Uncertain Not detected testis: 0.6 -C14orf119 FLJ20671 ENSG00000179933 Chromosome 14 open reading frame 119 14 23094765-23100462 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003638 Uncertain Supported Mitochondria
Cytosol Expressed in all smooth muscle: 70.0 -CCR8 CDw198, CKR-L1, CMKBR8, CMKBRL2, CY6, GPR-CY6, TER1 ENSG00000179934 Chemokine (C-C motif) receptor 8 3 39329706-39333511 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 urinary bladder: 2.4 appendix: 1.7 -GOLGA8J ENSG00000179938 Golgin A8 family, member J 15 30083053-30093499 Predicted intracellular proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -BBS10 C12orf58, FLJ23560 ENSG00000179941 Bardet-Biedl syndrome 10 12 76344474-76348442 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA047954, HPA058743 Approved Uncertain Nucleoplasm Mixed cerebral cortex: 16.7 -FIZ1 FLJ14768, ZNF798 ENSG00000179943 FLT3-interacting zinc finger 1 19 55591371-55601970 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA074026 Approved Nucleus Expressed in all parathyroid gland: 20.6 -PUF60 FIR, RoBPI, SIAHBP1 ENSG00000179950 Poly-U binding splicing factor 60KDa 8 143816344-143829859 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045733, HPA052096, HPA059714 Supported Validated Nucleoplasm Expressed in all testis: 26.2 -SSC5D FLJ35258 ENSG00000179954 Scavenger receptor cysteine rich family, 5 domains 19 55488404-55519098 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042008 Approved Approved Nucleoplasm
Cytosol Mixed smooth muscle: 31.7 -DCTPP1 CDA03, MGC5627, RS21C6, XTP3TPA ENSG00000179958 DCTP pyrophosphatase 1 16 30423619-30430075 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002832 Uncertain Approved Nucleoplasm
Cytosol Expressed in all rectum: 65.1 -ZNF771 DSC43 ENSG00000179965 Zinc finger protein 771 16 30407297-30431108 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030730, HPA046672, HPA059398 Uncertain Approved Nucleus
Nucleoli Mixed cerebral cortex: 7.1 -CRIPAK FLJ34443 ENSG00000179979 Cysteine-rich PAK1 inhibitor 4 1391552-1395989 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed skin: 15.0 -TSHZ1 NY-CO-33, SDCCAG33, TSH1 ENSG00000179981 Teashirt zinc finger homeobox 1 18 75210755-75289950 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA006982 Approved Approved Nucleoplasm Expressed in all ovary: 46.3 -PSTK C10orf89, MGC35392 ENSG00000179988 Phosphoseryl-tRNA kinase 10 122954381-122997513 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037780, HPA037781 Approved Approved Nucleoli
Nuclear bodies
Actin filaments Mixed testis: 5.6 -SOCS4 SOCS7 ENSG00000180008 Suppressor of cytokine signaling 4 14 55027230-55049488 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB013478, HPA057961 Approved Approved Nucleus
Cytosol Mixed thyroid gland: 12.5 -ZADH2 MGC45594 ENSG00000180011 Zinc binding alcohol dehydrogenase domain containing 2 18 75195108-75209348 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021468, HPA053646 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Expressed in all placenta: 51.9 -OR1E1 HGM071, OR13-66, OR17-2, OR17-32, OR1E5, OR1E6, OR1E9P ENSG00000180016 Olfactory receptor, family 1, subfamily E, member 1 17 3397104-3398410 G-protein coupled receptors, Predicted membrane proteins, Transporters No evidence No evidence No evidence Not detected testis: 0.1 -ZNF48 DKFZp762K013, FLJ31751, MGC43952, ZNF553 ENSG00000180035 Zinc finger protein 48 16 30378106-30400108 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023806 Uncertain Supported Mitochondria Mixed parathyroid gland: 11.6 -FAM71E2 C19orf16, DKFZp434G1729 ENSG00000180043 Family with sequence similarity 71, member E2 19 55354908-55363260 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 237 testis: 23.6 epididymis: 0.0 -C3orf80 ENSG00000180044 Chromosome 3 open reading frame 80 3 160225636-160228213 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047439 Uncertain Tissue enhanced 0 cerebral cortex: 1.9 duodenum: 0.5 -NKX2-6 CSX2, NKX4-2 ENSG00000180053 NK2 homeobox 6 8 23702451-23706598 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.0 -TMEM150B TMEM224 ENSG00000180061 Transmembrane protein 150B 19 55312801-55334048 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 duodenum: 71.8;small intestine: 67.8 lung: 18.9 -ANKRD18A FLJ35740, KIAA2015 ENSG00000180071 Ankyrin repeat domain 18A 9 38571358-38620660 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046346, HPA046695, HPA049923, HPA051288 Uncertain Supported Nucleoli
Cytosol Tissue enhanced 0 bone marrow: 12.0;testis: 11.5 thyroid gland: 3.8 -WFDC11 WAP11 ENSG00000180083 WAP four-disulfide core domain 11 20 45648563-45670270 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 13 epididymis: 114.5 testis: 9.1 -TMEM86B MGC30208 ENSG00000180089 Transmembrane protein 86B 19 55226639-55229264 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057689 Uncertain Approved Midbody
Centrosome Mixed gallbladder: 6.6 -OR3A1 OLFRA03, OR17-40, OR40 ENSG00000180090 Olfactory receptor, family 3, subfamily A, member 1 17 3291635-3292600 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 1.7 epididymis: 0.3 -SEPT1 DIFF6, PNUTL3 ENSG00000180096 Septin 1 16 30378133-30395991 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041566, HPA060339 Supported Uncertain Actin filaments Tissue enhanced 0 lymph node: 16.5;spleen: 11.5 tonsil: 6.2 -TRNAU1AP FLJ20503, SECP43, TRSPAP1 ENSG00000180098 TRNA selenocysteine 1 associated protein 1 1 28553085-28578545 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032068, HPA032069 Uncertain Approved Nucleoplasm
Cytosol Mixed skin: 8.2 -EXOC3 SEC6L1, Sec6p ENSG00000180104 Exocyst complex component 3 5 443158-471937 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037880 Approved Nucleoplasm
Mitochondria Expressed in all testis: 58.2 -TDRD6 bA446F17.4, CT41.2, NY-CO-45, SPATA36 ENSG00000180113 Tudor domain containing 6 6 46687875-46704319 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 42.6;thyroid gland: 20.3 spleen: 7.2 -C12orf40 FLJ40126 ENSG00000180116 Chromosome 12 open reading frame 40 12 39626167-39908300 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039031, HPA039032 Uncertain Tissue enriched 78 testis: 15.5 tonsil: 0.2 -CSNK1A1L MGC33182 ENSG00000180138 Casein kinase 1, alpha 1-like 13 37103259-37105664 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051334 Uncertain Cytosol Tissue enriched 16 testis: 6.4 bone marrow: 0.3 -LYNX1 SLURP2 ENSG00000180155 Ly6/neurotoxin 1 8 142764334-142778224 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023711 Approved Tissue enhanced 0 esophagus: 346.7 skin: 140.2 -TH DYT5b ENSG00000180176 Tyrosine hydroxylase 11 2163929-2171877 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002522, HPA061003, CAB072340 Supported Supported Tissue enriched 81 adrenal gland: 261.2 adipose tissue: 3.2 -MED14 CRSP150, CRSP2, CSRP, CXorf4, EXLM1, RGR1, TRAP170 ENSG00000180182 Mediator complex subunit 14 X 40648306-40735858 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064182 Approved Nucleoplasm Expressed in all parathyroid gland: 31.6 -FAHD1 C16orf36, DKFZP566J2046 ENSG00000180185 Fumarylacetoacetate hydrolase domain containing 1 16 1826941-1840207 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025530, HPA043226, HPA043534 Supported Validated Nucleus
Mitochondria Expressed in all kidney: 65.8 -TDRP C8orf42, INM01, TDRP1, TDRP2 ENSG00000180190 Testis development related protein 8 489792-545781 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008462 Approved Supported Vesicles
Cytosol Mixed placenta: 46.5 -RCC1 CHC1 ENSG00000180198 Regulator of chromosome condensation 1 1 28505943-28539300 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015413, HPA027573, HPA027574 Supported Supported Nucleus
Nuclear membrane Expressed in all testis: 63.6 -WFDC9 dJ688G8.2, WAP9 ENSG00000180205 WAP four-disulfide core domain 9 20 45607939-45631268 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 403 epididymis: 1236.5 seminal vesicle: 3.0 -MYLPF HUMMLC2B, MRLC2, MYL11 ENSG00000180209 Myosin light chain, phosphorylatable, fast skeletal muscle 16 30370934-30377991 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039262 Approved Tissue enriched 94 skeletal muscle: 6542.5 esophagus: 69.5 -F2 ENSG00000180210 Coagulation factor II (thrombin) 11 46719180-46739506 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016780, CAB018650, HPA051476, HPA054698 Supported Tissue enriched 1471 liver: 627.1 testis: 0.4 -FAM71C MGC39520 ENSG00000180219 Family with sequence similarity 71, member C 12 99647753-99650046 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 311 testis: 31.0 adipose tissue: 0.0 -PRKRA DYT16, HSD14, PACT, RAX ENSG00000180228 Protein kinase, interferon-inducible double stranded RNA dependent activator 2 178431414-178451512 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004648, HPA034996, HPA034997 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 56.2 -ZNRF2 RNF202 ENSG00000180233 Zinc and ring finger 2, E3 ubiquitin protein ligase 7 30284307-30367692 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 39.5 -RRH peropsin ENSG00000180245 Retinal pigment epithelium-derived rhodopsin homolog 4 109827994-109844604 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Not detected cerebral cortex: 0.5 -SLC9A4 NHE4 ENSG00000180251 Solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 2 102473303-102533972 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036096 Approved Approved Nucleoplasm
Plasma membrane Tissue enriched 5 stomach: 51.1 kidney: 9.5 -ZNF816 ZNF816A ENSG00000180257 Zinc finger protein 816 19 52949379-52962911 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042466 Uncertain Uncertain Nucleoli Mixed prostate: 20.4 -PRNT M8 ENSG00000180259 Prion protein (testis specific) 20 4731282-4740668 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA045000 Uncertain Tissue enriched 109 testis: 10.9 epididymis: 0.0 -FGD6 FLJ11183, ZFYVE24 ENSG00000180263 FYVE, RhoGEF and PH domain containing 6 12 95076749-95217482 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007974 Approved Approved Vesicles Mixed skin: 9.4 -ADGRD2 GPR144, PGR24 ENSG00000180264 Adhesion G protein-coupled receptor D2 9 124451600-124478589 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 2.3;seminal vesicle: 5.6 breast: 1.4 -GPR139 PGR3 ENSG00000180269 G protein-coupled receptor 139 16 20031485-20073917 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA046596 Uncertain Not detected endometrium: 0.3 -PLD5 FLJ40773 ENSG00000180287 Phospholipase D family, member 5 1 242082986-242524696 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028389, HPA050367 Uncertain Approved Vesicles
Mitochondria
Cytosol Mixed cerebral cortex: 4.2 -OAZ2 ENSG00000180304 Ornithine decarboxylase antizyme 2 15 64687573-64703281 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047694 Uncertain Approved Golgi apparatus Expressed in all parathyroid gland: 115.7 -WFDC10A C20orf146, dJ688G8.3, WAP10 ENSG00000180305 WAP four-disulfide core domain 10A 20 45629526-45631196 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 303 epididymis: 177.7 seminal vesicle: 0.5 -PNPLA1 dJ50J22.1, FLJ38755 ENSG00000180316 Patatin-like phospholipase domain containing 1 6 36243203-36308595 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA037853 Uncertain Intermediate filaments Tissue enriched 6 skin: 28.8 kidney: 4.6 -ALX1 CART1 ENSG00000180318 ALX homeobox 1 12 85280107-85301784 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001598, HPA018905 Uncertain Supported Nucleoplasm
Nuclear bodies
Golgi apparatus Tissue enhanced 0 epididymis: 4.2;kidney: 3.1 ovary: 1.8 -CCDC43 FLJ31795 ENSG00000180329 Coiled-coil domain containing 43 17 44673069-44689779 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023391 Approved Validated Cytosol Expressed in all skeletal muscle: 26.1 -KCTD4 bA321C24.3 ENSG00000180332 Potassium channel tetramerization domain containing 4 13 45192853-45194717 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040734 Uncertain Approved Microtubule organizing center Group enriched 10 cerebral cortex: 17.7;skin: 3.7 gallbladder: 1.1 -C17orf104 FLJ35848 ENSG00000180336 Chromosome 17 open reading frame 104 17 44656404-44690308 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027266 Uncertain Uncertain Cell Junctions Tissue enriched 51 testis: 85.8 cerebral cortex: 1.6 -FZD2 ENSG00000180340 Frizzled class receptor 2 17 44557459-44559570 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057667 Uncertain Approved Nuclear bodies
Cell Junctions Mixed placenta: 4.9 -TIGD2 ENSG00000180346 Tigger transposable element derived 2 4 89111500-89114899 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA054844, HPA071168 Uncertain Approved Nuclear bodies Mixed parathyroid gland: 17.6 -CCDC129 FLJ38344 ENSG00000180347 Coiled-coil domain containing 129 7 31514071-31658720 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA024103 Uncertain Uncertain Nucleoplasm Tissue enhanced 0 cervix, uterine: 2.6;salivary gland: 2.4 testis: 2.1 -HCLS1 CTTNL, HS1 ENSG00000180353 Hematopoietic cell-specific Lyn substrate 1 3 121631399-121660927 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019143 Supported Supported Plasma membrane
Cytosol Expressed in all spleen: 275.8 -MTURN C7orf41, Ells1, FLJ25903 ENSG00000180354 Maturin, neural progenitor differentiation regulator homolog (Xenopus) 7 30134810-30162762 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029507 Approved Approved Cytosol Expressed in all cerebral cortex: 352.3 -ZNF609 KIAA0295 ENSG00000180357 Zinc finger protein 609 15 64460742-64686068 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040742, HPA040832 Approved Validated Nucleoplasm
Cytosol Expressed in all testis: 40.8 -PAK2 PAK65, PAKgamma ENSG00000180370 P21 protein (Cdc42/Rac)-activated kinase 2 3 196739857-196832647 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007794 Approved Supported Nucleus
Vesicles Expressed in all spleen: 61.0 -CCDC66 DKFZp686C0433 ENSG00000180376 Coiled-coil domain containing 66 3 56557161-56621818 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044185 Uncertain Approved Cell Junctions
Midbody ring
Microtubule organizing center Mixed fallopian tube: 9.5 -DEFB124 DEFB-24 ENSG00000180383 Defensin, beta 124 20 31465506-31476757 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA051046 Uncertain Tissue enhanced 0 fallopian tube: 8.7;testis: 5.8 endometrium: 5.3 -KRTAP9-7 KAP9.7, KRTAP9L1 ENSG00000180386 Keratin associated protein 9-7 17 41275659-41276697 Predicted intracellular proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -ATP5EP2 ENSG00000180389 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2 13 27945206-27945590 Predicted intracellular proteins No evidence No evidence No evidence Not detected stomach: 0.2 -MCFD2 F5F8D, LMAN1IP, SDNSF ENSG00000180398 Multiple coagulation factor deficiency 2 2 46901870-46941855 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022410, HPA034593 Supported Expressed in all adrenal gland: 207.9 -HARBI1 C11orf77, FLJ32675 ENSG00000180423 Harbinger transposase derived 1 11 46602861-46617909 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038671, HPA045457 Uncertain Validated Plasma membrane
Cytosol Tissue enhanced 0 testis: 21.7 parathyroid gland: 5.2 -DEFB123 DEFB-23 ENSG00000180424 Defensin, beta 123 20 31440519-31450257 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 426 epididymis: 106.1;testis: 176.9 small intestine: 0.3 -C11orf71 FLJ20010 ENSG00000180425 Chromosome 11 open reading frame 71 11 114391443-114400550 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA063943, HPA074787 Approved Nucleoplasm Tissue enriched 518 testis: 53.6 liver: 0.1 -CYP8B1 CYP12 ENSG00000180432 Cytochrome P450, family 8, subfamily B, polypeptide 1 3 42856005-42876165 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 14 liver: 190.6 kidney: 13.7 -OR6K6 ENSG00000180433 Olfactory receptor, family 6, subfamily K, member 6 1 158754720-158755891 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -TPRXL FLJ35107 ENSG00000180438 Tetra-peptide repeat homeobox-like 3 13937256-14082811 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed testis: 16.7 -SERTM1 C13orf36 ENSG00000180440 Serine-rich and transmembrane domain containing 1 13 36673912-36697839 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA054814, HPA070485 Uncertain Supported Vesicles Tissue enhanced 0 cerebral cortex: 47.8;endometrium: 37.3;fallopian tube: 29.3 smooth muscle: 24.5 -GAS1 ENSG00000180447 Growth arrest-specific 1 9 86944363-86947189 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB024164, HPA036085, HPA066902 Approved Approved Nuclear speckles Tissue enhanced 0 endometrium: 110.4 smooth muscle: 73.6 -HMHA1 ARHGAP45, HA-1, KIAA0223 ENSG00000180448 Histocompatibility (minor) HA-1 19 1065923-1086628 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019816 Supported Tissue enhanced 0 appendix: 58.4;lymph node: 67.5;spleen: 79.4 bone marrow: 44.1 -OR10Q1 ENSG00000180475 Olfactory receptor, family 10, subfamily Q, member 1 11 58227882-58228918 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA046968 Uncertain Not detected placenta: 0.1 -ZNF571 HSPC059 ENSG00000180479 Zinc finger protein 571 19 37554782-37594790 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA054762 Approved Nucleus
Nucleoli
Plasma membrane Tissue enriched 5 thyroid gland: 130.2 testis: 25.9 -GLIPR1L2 MGC39497 ENSG00000180481 GLI pathogenesis-related 1 like 2 12 75391070-75432688 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039795, HPA039866 Supported Tissue enriched 8 testis: 84.5 parathyroid gland: 11.0 -DEFB119 DEFB-19, DEFB-20, DEFB120 ENSG00000180483 Defensin, beta 119 20 31377164-31390603 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043059 Approved Group enriched 3354 epididymis: 2302.6;testis: 469.2 duodenum: 0.4 -FAM73A FLJ35093 ENSG00000180488 Family with sequence similarity 73, member A 1 77779624-77879539 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017589 Approved Supported Mitochondria Expressed in all parathyroid gland: 32.2 -KCNE1 ISK, JLNS2, LQT5, minK ENSG00000180509 Potassium channel, voltage gated subfamily E regulatory beta subunit 1 21 34446688-34512275 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 fallopian tube: 16.4 heart muscle: 3.7 -PRR26 C10orf108, FLJ38681 ENSG00000180525 Proline rich 26 10 649948-669581 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA066037 Uncertain Mixed gallbladder: 7.9 -NRIP1 RIP140 ENSG00000180530 Nuclear receptor interacting protein 1 21 14961235-15065000 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046571, HPA060036 Approved Approved Nucleus
Nucleoli Expressed in all cervix: 38.8 -ZSCAN4 FLJ35105, ZNF494 ENSG00000180532 Zinc finger and SCAN domain containing 4 19 57668935-57679152 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA006491 Uncertain Tissue enhanced 0 stomach: 2.4 placenta: 1.2 -BHLHA15 bHLHa15, BHLHB8, MIST1 ENSG00000180535 Basic helix-loop-helix family, member a15 7 98211427-98212979 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034083, HPA047834 Supported Approved Nucleoplasm
Golgi apparatus Group enriched 9 pancreas: 85.5;salivary gland: 54.2 prostate: 7.9 -RNF182 MGC33993 ENSG00000180537 Ring finger protein 182 6 13924446-13980302 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA012309 Approved Approved Nucleus
Golgi apparatus
Vesicles Tissue enhanced 0 cerebral cortex: 14.6 testis: 6.8 -TSPYL5 KIAA1750 ENSG00000180543 TSPY-like 5 8 97273474-97277964 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031347 Supported Approved Golgi apparatus
Cytosol Tissue enhanced 0 testis: 81.1 ovary: 30.3 -FUT7 ENSG00000180549 Fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 9 137030174-137033010 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042780 Approved Golgi apparatus Tissue enhanced 0 lymph node: 3.7;spleen: 2.7 tonsil: 2.1 -HIST1H2AC H2AFL ENSG00000180573 Histone cluster 1, H2ac 6 26124145-26139116 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Expressed in all prostate: 56.2 -EIF2S3L ENSG00000180574 Putative eukaryotic translation initiation factor 2 subunit 3-like protein 12 10505602-10523135 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 testis: 4.4 duodenum: 1.1 -SKIDA1 C10orf140, FLJ45187 ENSG00000180592 SKI/DACH domain containing 1 10 21513478-21526368 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039208, HPA040439 Uncertain Tissue enhanced 0 parathyroid gland: 4.0 testis: 3.1 -HIST1H2BC H2B.1, H2B/l, H2BFL ENSG00000180596 Histone cluster 1, H2bc 6 26114873-26123926 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 prostate: 32.1 bone marrow: 16.6 -MB21D2 C3orf59 ENSG00000180611 Mab-21 domain containing 2 3 192796815-192918161 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044026 Uncertain Approved Cytosol Mixed placenta: 17.0 -GSX2 Gsh2 ENSG00000180613 GS homeobox 2 4 54099523-54102505 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.4 -SSTR2 ENSG00000180616 Somatostatin receptor 2 17 73165012-73176633 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007264 Uncertain Supported Cytosol Tissue enhanced 0 cerebral cortex: 22.9 spleen: 5.9 -ZNF594 KIAA1871 ENSG00000180626 Zinc finger protein 594 17 5179536-5191883 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA067178 Approved Nucleus Mixed ovary: 13.8 -PCGF5 MGC16202, RNF159 ENSG00000180628 Polycomb group ring finger 5 10 91163012-91284331 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038349 Approved Supported Nucleoli Expressed in all thyroid gland: 40.3 -SLC47A2 FLJ31196, MATE2, MATE2-K ENSG00000180638 Solute carrier family 47 (multidrug and toxin extrusion), member 2 17 19678288-19718979 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 fallopian tube: 16.0;kidney: 48.9 epididymis: 6.0 -PRF1 HPLH2, P1, PFP ENSG00000180644 Perforin 1 (pore forming protein) 10 70597348-70602775 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002436, HPA037940 Approved Approved Cytosol Tissue enhanced 0 spleen: 54.5 lymph node: 21.2 -OR2A4 OR2A10 ENSG00000180658 Olfactory receptor, family 2, subfamily A, member 4 6 131700469-131701401 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA058272 Uncertain Not detected testis: 0.2 -MAB21L1 CAGR1 ENSG00000180660 Mab-21-like 1 (C. elegans) 13 35474182-35477209 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049324, HPA059864 Approved Nucleoplasm Tissue enhanced 0 adrenal gland: 5.5;breast: 5.6 adipose tissue: 2.5 -YOD1 DKFZp451J1719, DUBA8, OTUD2 ENSG00000180667 YOD1 deubiquitinase 1 207043849-207052980 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028400, HPA028439 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 bone marrow: 37.2 esophagus: 27.9 -TMEM64 DKFZp762C1112 ENSG00000180694 Transmembrane protein 64 8 90621995-90791632 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB034221 Uncertain Expressed in all epididymis: 173.0 -C3orf22 MGC34728 ENSG00000180697 Chromosome 3 open reading frame 22 3 126526999-126558965 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA059199 Supported Tissue enriched 326 testis: 32.5 epididymis: 0.0 -OR10K2 ENSG00000180708 Olfactory receptor, family 10, subfamily K, member 2 1 158419928-158420866 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA059125 Uncertain Not detected adipose tissue: 0.0 -CHRM4 ENSG00000180720 Cholinergic receptor, muscarinic 4 11 46385098-46386608 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB022444, HPA072083 Uncertain Uncertain Nucleus
Golgi apparatus Tissue enhanced 0 cerebral cortex: 8.1;small intestine: 7.9;spleen: 21.9 testis: 6.9 -SHISA2 bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166 ENSG00000180730 Shisa family member 2 13 26044597-26051031 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049752, HPA050172 Uncertain Approved Nucleoplasm
Nuclear bodies
Vesicles Tissue enhanced 0 breast: 21.9;thyroid gland: 48.1 epididymis: 12.9 -S1PR5 Edg-8, EDG8 ENSG00000180739 Sphingosine-1-phosphate receptor 5 19 10512742-10517931 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029683 Supported Tissue enhanced 0 cerebral cortex: 14.9;skin: 22.1 spleen: 12.2 -CLRN3 MGC32871, TMEM12, USH3AL1 ENSG00000180745 Clarin 3 10 127877841-127892947 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014482 Approved Group enriched 8 colon: 71.2;duodenum: 75.4;gallbladder: 23.7;kidney: 43.9;liver: 40.2;rectum: 77.5;small intestine: 99.5 appendix: 7.5 -GPR157 FLJ12132 ENSG00000180758 G protein-coupled receptor 157 1 9100305-9129170 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028697 Uncertain Uncertain Nucleoli
Plasma membrane
Cell Junctions Mixed parathyroid gland: 23.9 -CHST13 C4ST3 ENSG00000180767 Carbohydrate (chondroitin 4) sulfotransferase 13 3 126524283-126543291 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 liver: 5.9;testis: 6.3 spleen: 2.9 -AGTR2 AT2, MRX88 ENSG00000180772 Angiotensin II receptor, type 2 X 116170722-116174972 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 6 cervix, uterine: 6.8;endometrium: 13.8;fallopian tube: 3.8;lung: 12.6;smooth muscle: 17.4 adrenal gland: 1.9 -SLC36A4 FLJ38932, PAT4 ENSG00000180773 Solute carrier family 36 (proton/amino acid symporter), member 4 11 93144171-93197964 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017887 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Mixed thyroid gland: 14.7 -ZDHHC20 FLJ25952 ENSG00000180776 Zinc finger, DHHC-type containing 20 13 21372573-21459370 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014483, HPA014702 Approved Uncertain Vesicles
Plasma membrane
Mitochondria Expressed in all testis: 60.4 -ANKRD30B NY-BR-1.1 ENSG00000180777 Ankyrin repeat domain 30B 18 14728272-14852738 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA060455 Uncertain Tissue enriched 11 testis: 14.3 breast: 1.3 -OR51E1 GPR136, GPR164, OR51E1P, OR52A3P ENSG00000180785 Olfactory receptor, family 51, subfamily E, member 1 11 4643420-4655488 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB019995, HPA051439 Approved Tissue enhanced 0 adipose tissue: 6.3;placenta: 9.5;prostate: 8.0 urinary bladder: 1.8 -ZFP3 FLJ30726, ZNF752 ENSG00000180787 ZFP3 zinc finger protein 17 5078248-5096374 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA053085, HPA057290 Approved Approved Nucleoplasm
Cytosol Mixed parathyroid gland: 12.8 -ARSJ FLJ23548 ENSG00000180801 Arylsulfatase family, member J 4 113900284-113979727 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036481, HPA036482 Uncertain Supported Nucleoli
Actin filaments Mixed parathyroid gland: 12.5 -HOXC9 HOX3, HOX3B ENSG00000180806 Homeobox C9 12 53994895-54003337 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063965, HPA072160 Validated Nucleoplasm Tissue enhanced 0 skeletal muscle: 6.2 adipose tissue: 3.3 -MAP3K15 ASK3, bA723P2.3, FLJ16518 ENSG00000180815 Mitogen-activated protein kinase kinase kinase 15 X 19360056-19515261 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004006 Approved Vesicles Tissue enriched 6 adrenal gland: 14.4 spleen: 2.4 -PPA1 IOPPP, PP, PP1, Ppase, SID6-8061 ENSG00000180817 Pyrophosphatase (inorganic) 1 10 70202830-70233911 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019878, HPA020096 Supported Supported Vesicles Expressed in all breast: 225.4 -HOXC10 HOX3I ENSG00000180818 Homeobox C10 12 53985065-53990279 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053919 Uncertain Supported Nuclear bodies Group enriched 8 kidney: 18.8;skeletal muscle: 40.3;skin: 8.4 breast: 2.6 -PSMG4 C6orf86, PAC4 ENSG00000180822 Proteasome (prosome, macropain) assembly chaperone 4 6 3231403-3303373 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA067652 Approved Nucleus
Mitochondria Expressed in all epididymis: 26.3 -BHLHE22 Beta3, BHLHB5, bHLHe22, CAGL85, TNRC20 ENSG00000180828 Basic helix-loop-helix family, member e22 8 64580367-64583628 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA064128, HPA064872, HPA067500 Supported Tissue enhanced 0 cerebral cortex: 12.2 seminal vesicle: 3.3 -MAP6D1 FLJ12748, SL21 ENSG00000180834 MAP6 domain containing 1 3 183815876-183825594 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037991 Approved Cytosol Group enriched 7 cerebral cortex: 43.2;skeletal muscle: 11.0 skin: 4.1 -ZNF443 ZK1 ENSG00000180855 Zinc finger protein 443 19 12429707-12441112 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA003150, HPA018683 Supported Uncertain Nucleoplasm
Microtubule organizing center Mixed parathyroid gland: 6.9 -CXCR2 CD182, CMKAR2, IL8RB ENSG00000180871 Chemokine (C-X-C motif) receptor 2 2 218125289-218137253 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016268, HPA031999, HPA032017 Supported Tissue enhanced 0 appendix: 56.9;spleen: 37.2 esophagus: 30.0 -DEFB112 DEFB-12 ENSG00000180872 Defensin, beta 112 6 50043575-50048651 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 55 epididymis: 176.3 seminal vesicle: 3.1 -GREM2 CKTSF1B2, DAND3, FLJ21195, Prdc ENSG00000180875 Gremlin 2, DAN family BMP antagonist 1 240489573-240612149 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB009920 Approved Tissue enhanced 0 gallbladder: 49.0;parathyroid gland: 77.1 rectum: 22.9 -C11orf42 MGC34805 ENSG00000180878 Chromosome 11 open reading frame 42 11 6205566-6211132 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA063404 Supported Tissue enriched 11 testis: 20.4 skin: 1.8 -SSR4 TRAPD ENSG00000180879 Signal sequence receptor, delta X 153793516-153798505 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045209 Supported Expressed in all epididymis: 962.9 -CAPS2 ENSG00000180881 Calcyphosine 2 12 75275979-75390928 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040004 Uncertain Approved Nucleus
Nucleoli
Centrosome Tissue enhanced 0 fallopian tube: 15.6 thyroid gland: 6.8 -ZNF792 FLJ38451 ENSG00000180884 Zinc finger protein 792 19 34956354-34964049 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA035157, HPA035158 Supported Approved Nucleoplasm
Nuclear bodies Mixed lung: 6.2 -CUEDC1 ENSG00000180891 CUE domain containing 1 17 57861243-57955323 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023050, HPA024836 Approved Uncertain Centrosome
Mitochondria
Cytosol Expressed in all fallopian tube: 51.8 -SCRIB KIAA0147, SCRB1, Vartul ENSG00000180900 Scribbled planar cell polarity protein 8 143790920-143815379 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015463, CAB022081, HPA023557, HPA064312 Supported Validated Nucleoplasm
Plasma membrane
Cell Junctions
Rods & Rings Expressed in all skin: 22.0 -KCTD2 KIAA0176 ENSG00000180901 Potassium channel tetramerization domain containing 2 17 75032575-75065889 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adipose tissue: 3.4;cerebral cortex: 7.3 kidney: 2.0 -D2HGDH D2HGD, FLJ42195, MGC25181 ENSG00000180902 D-2-hydroxyglutarate dehydrogenase 2 241734579-241768816 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056216 Uncertain Expressed in all skin: 46.4 -OXTR ENSG00000180914 Oxytocin receptor 3 8750408-8769628 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 11 breast: 65.6 fallopian tube: 6.0 -CMTR2 AFT, FLJ11171, FTSJD1, MTr2 ENSG00000180917 Cap methyltransferase 2 16 71281389-71289715 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041700, HPA048265 Uncertain Approved Nuclear speckles
Cell Junctions Mixed testis: 16.2 -OR56B4 ENSG00000180919 Olfactory receptor, family 56, subfamily B, member 4 11 6107684-6108835 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected smooth muscle: 0.2 -FAM83H FLJ46072 ENSG00000180921 Family with sequence similarity 83, member H 8 143723933-143733801 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024505, HPA024604 Approved Approved Cytosol Tissue enhanced 0 skin: 17.2 esophagus: 10.4 -GPR62 ENSG00000180929 G protein-coupled receptor 62 3 51955314-51957504 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 13 cerebral cortex: 8.0 ovary: 0.6 -OR56A1 ENSG00000180934 Olfactory receptor, family 56, subfamily A, member 1 11 6026671-6027741 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.6 -ZNF572 FLJ38002 ENSG00000180938 Zinc finger protein 572 8 124973298-124979389 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA066838 Approved Approved Nuclear speckles Mixed testis: 6.7 -ST20 HCCS-1 ENSG00000180953 Suppressor of tumorigenicity 20 15 79898840-79923702 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed spleen: 11.6 -PITPNB VIB1B ENSG00000180957 Phosphatidylinositol transfer protein, beta 22 27851669-27920134 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000528 Uncertain Approved Vesicles
Cytosol Expressed in all placenta: 70.1 -TCEAL8 MGC45400, WEX3 ENSG00000180964 Transcription elongation factor A (SII)-like 8 X 103252995-103255203 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA059115 Uncertain Approved Nucleoplasm Expressed in all epididymis: 147.2 -OR52E4 ENSG00000180974 Olfactory receptor, family 52, subfamily E, member 4 11 5884271-5885300 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.2 -LRRC57 FLJ36812 ENSG00000180979 Leucine rich repeat containing 57 15 42537820-42548802 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040894 Approved Approved Mitochondria
Cytosol Expressed in all bone marrow: 14.9 -OR52N2 ENSG00000180988 Olfactory receptor, family 52, subfamily N, member 2 11 5820314-5821348 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.8 -MRPL14 MRP-L32, RPML32 ENSG00000180992 Mitochondrial ribosomal protein L14 6 44113454-44127457 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038769, HPA076790 Uncertain Supported Mitochondria Expressed in all lung: 85.7 -GPR137C DKFZp762F0713, TM7SF1L2 ENSG00000180998 G protein-coupled receptor 137C 14 52553148-52637713 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003640, HPA030763 Uncertain Approved Vesicles Tissue enhanced 0 cerebral cortex: 18.0;epididymis: 10.5 testis: 8.2 -C1orf105 ENSG00000180999 Chromosome 1 open reading frame 105 1 172420688-172468831 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 testis: 46.1 epididymis: 7.1 -OR52N1 ENSG00000181001 Olfactory receptor, family 52, subfamily N, member 1 11 5787854-5788816 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA054028 Uncertain Not detected adipose tissue: 0.1 -BBS12 C4orf24, FLJ35630, FLJ41559 ENSG00000181004 Bardet-Biedl syndrome 12 4 122732702-122744943 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA061856 Approved Mixed thyroid gland: 15.9 -ZFP82 KIAA1948, MGC45380, ZNF545 ENSG00000181007 ZFP82 zinc finger protein 19 36383120-36418656 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060470 Uncertain Mixed thyroid gland: 8.8 -OR52N5 OR52N5Q ENSG00000181009 Olfactory receptor, family 52, subfamily N, member 5 11 5777634-5778667 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -C17orf47 FLJ40121 ENSG00000181013 Chromosome 17 open reading frame 47 17 58541587-58544368 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA028424 Approved Tissue enriched 12 testis: 16.4 placenta: 1.3 -LSMEM1 C7orf53, FLJ39575 ENSG00000181016 Leucine-rich single-pass membrane protein 1 7 112480853-112491062 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA013753, HPA047988 Uncertain Supported Cytosol Tissue enriched 11 skeletal muscle: 31.8 testis: 2.8 -NQO1 DHQU, DIA4, DTD, NMOR1, QR1 ENSG00000181019 NAD(P)H dehydrogenase, quinone 1 16 69706996-69726951 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007308, CAB012421 Supported Validated Cytosol Tissue enhanced 0 breast: 371.7;stomach: 559.0 gallbladder: 321.6 -OR56B1 OR56B1P ENSG00000181023 Olfactory receptor, family 56, subfamily B, member 1 11 5736517-5737491 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA045043 Uncertain Not detected parathyroid gland: 0.3 -AEN FLJ12484, FLJ12562, ISG20L1 ENSG00000181026 Apoptosis enhancing nuclease 15 88621296-88632282 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048599 Supported Nucleus
Nuclear membrane
Nucleoli Mixed gallbladder: 19.8 -FKRP LGMD2I, MDC1C ENSG00000181027 Fukutin related protein 19 46746046-46776988 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043115, HPA060454 Approved Approved Nucleus
Golgi apparatus
Cytosol Expressed in all placenta: 14.8 -TRAPPC5 MGC52424, TRS31 ENSG00000181029 Trafficking protein particle complex 5 19 7680843-7687703 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042221, HPA049064 Uncertain Approved Vesicles Expressed in all testis: 70.0 -RPH3AL Noc2 ENSG00000181031 Rabphilin 3A-like (without C2 domains) 17 212389-386254 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024311 Approved Mixed spleen: 11.9 -SLC25A42 MGC26694 ENSG00000181035 Solute carrier family 25, member 42 19 19063999-19112888 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049449 Approved Supported Mitochondria Expressed in all kidney: 28.7 -FCRL6 FcRH6, FLJ16056, IFGP6 ENSG00000181036 Fc receptor-like 6 1 159800511-159816251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 spleen: 18.7 lung: 9.0 -METTL23 C17orf95, LOC124512 ENSG00000181038 Methyltransferase like 23 17 76726830-76733936 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all testis: 85.6 -SLC26A11 ENSG00000181045 Solute carrier family 26 (anion exchanger), member 11 17 80219699-80253500 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029893 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Expressed in all adrenal gland: 34.5 -HIGD1A DKFZP564K247, HIG1 ENSG00000181061 HIG1 hypoxia inducible domain family, member 1A 3 42784298-42804531 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043336 Approved Supported Nucleoplasm
Mitochondria Expressed in all rectum: 333.6 -CHRM2 ENSG00000181072 Cholinergic receptor, muscarinic 2 7 136868669-137020255 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022338, HPA029795 Approved Tissue enhanced 0 gallbladder: 18.4;heart muscle: 26.7;smooth muscle: 13.6 urinary bladder: 6.1 -OR52N4 ENSG00000181074 Olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene) 11 5754693-5755729 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed spleen: 2.5 -MAPK15 ERK7, ERK8 ENSG00000181085 Mitogen-activated protein kinase 15 8 143716259-143722458 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA002704 Approved Nucleoplasm
Cell Junctions
Cytosol Tissue enhanced 0 fallopian tube: 43.3 parathyroid gland: 13.2 -EHMT1 bA188C12.1, Eu-HMTase1, FLJ12879, KIAA1876, KMT1D ENSG00000181090 Euchromatic histone-lysine N-methyltransferase 1 9 137618963-137870016 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060022 Supported Nucleoplasm
Nuclear bodies Expressed in all testis: 75.6 -ADIPOQ ACDC, ACRP30, adiponectin, AdipoQ, apM1, GBP28 ENSG00000181092 Adiponectin, C1Q and collagen domain containing 3 186842690-186858463 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046467, HPA051767 Uncertain Tissue enriched 17 adipose tissue: 935.8 breast: 55.7 -F2R CF2R, PAR-1, PAR1, TR ENSG00000181104 Coagulation factor II (thrombin) receptor 5 76716043-76735781 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008973, CAB012962 Approved Expressed in all spleen: 95.4 -ZNF707 ENSG00000181135 Zinc finger protein 707 8 143684452-143713898 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044991 Approved Validated Nucleoplasm Mixed skin: 4.9 -MUC16 CA125, FLJ14303 ENSG00000181143 Mucin 16, cell surface associated 19 8848844-8981342 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB055172 Supported Tissue enhanced 0 cervix, uterine: 23.8;fallopian tube: 9.3 endometrium: 3.5 -NPM1 B23, NPM ENSG00000181163 Nucleophosmin (nucleolar phosphoprotein B23, numatrin) 5 171387116-171411137 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011384, CAB012983 Supported Validated Nucleus
Nucleoli Expressed in all ovary: 1797.0 -PJA1 FLJ11830, RNF70 ENSG00000181191 Praja ring finger 1, E3 ubiquitin protein ligase X 69160851-69165793 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000595 Approved Approved Nucleus
Nucleoli Expressed in all epididymis: 178.2 -DHTKD1 CMT2Q, DKFZP762M115, KIAA1630, MGC3090 ENSG00000181192 Dehydrogenase E1 and transketolase domain containing 1 10 12068972-12123225 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037949, HPA037950, HPA066098 Approved Supported Mitochondria Expressed in all liver: 66.5 -PENK ENSG00000181195 Proenkephalin 8 56436674-56446734 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013138, CAB016390 Supported Group enriched 8 adrenal gland: 568.1;testis: 207.8 prostate: 47.7 -C4orf50 FLJ46481 ENSG00000181215 Chromosome 4 open reading frame 50 4 5897591-5989818 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058292 Uncertain Tissue enriched 10 cerebral cortex: 3.6 prostate: 0.3 -HIST3H2A MGC3165 ENSG00000181218 Histone cluster 3, H2a 1 228456979-228457873 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enhanced 0 adrenal gland: 22.8 cerebral cortex: 10.7 -ZNF746 FLJ31413, PARIS ENSG00000181220 Zinc finger protein 746 7 149472794-149497817 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020272 Approved Expressed in all testis: 23.2 -POLR2A POLR2, POLRA, RPB1 ENSG00000181222 Polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 17 7484366-7514618 Enzymes, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012226, CAB016388, HPA021563, CAB022311, HPA053012 Supported Validated Nucleoplasm Expressed in all testis: 117.8 -TMEM132C DKFZp761O2018, PPP1R152 ENSG00000181234 Transmembrane protein 132C 12 128267403-128707915 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA015633, HPA015984 Uncertain Supported Centrosome
Cytosol Tissue enhanced 0 adipose tissue: 34.7;cervix, uterine: 23.9 fallopian tube: 15.8 -SLC25A41 APC4, FLJ40442, MGC34725 ENSG00000181240 Solute carrier family 25, member 41 19 6426037-6433779 Predicted intracellular proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043591 Uncertain Tissue enhanced 0 cerebral cortex: 1.0;testis: 1.9 esophagus: 0.4 -TMEM136 MGC17839 ENSG00000181264 Transmembrane protein 136 11 120325129-120333682 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA074432 Approved Vesicles
Cytosol Mixed adrenal gland: 12.7 -OR5AK2 ENSG00000181273 Olfactory receptor, family 5, subfamily AK, member 2 11 56988872-56989867 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 66 spleen: 10.1 placenta: 0.1 -FRAT2 ENSG00000181274 Frequently rearranged in advanced T-cell lymphomas 2 10 97332497-97334709 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049763 Uncertain Approved Nucleus
Mitochondria Expressed in all duodenum: 26.2 -TMEM102 CBAP, FLJ36878 ENSG00000181284 Transmembrane protein 102 17 7435443-7437679 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024433 Uncertain Mixed adrenal gland: 7.1 -TMEM132E DFNB99 ENSG00000181291 Transmembrane protein 132E 17 34580749-34639318 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA070608 Approved Group enriched 5 cerebral cortex: 4.8;duodenum: 1.7;kidney: 3.2;small intestine: 1.1;testis: 1.5 cervix: 0.4 -ZNF322 bA457M11.2, bA457M11.3, HCG12, ZNF322A, ZNF388, ZNF489 ENSG00000181315 Zinc finger protein 322 6 26634383-26659752 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA043161, HPA046692 Approved Supported Nucleus
Centrosome
Cytosol Mixed parathyroid gland: 28.7 -NME9 NM23-H9, TXL-2, TXNDC6 ENSG00000181322 NME/NM23 family member 9 3 138261437-138329886 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA040000, HPA043881 Supported Tissue enhanced 0 fallopian tube: 29.9 testis: 6.9 -SPEM1 C17orf83, FLJ40081 ENSG00000181323 Spermatid maturation 1 17 7420360-7421632 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 641 testis: 64.0 adipose tissue: 0.0 -HEPHL1 DKFZp686F22190 ENSG00000181333 Hephaestin-like 1 11 94021361-94113751 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA031517 Uncertain Group enriched 11 esophagus: 3.2;tonsil: 9.8 testis: 0.6 -LRRC75A C17orf76, FAM211A, FLJ35696 ENSG00000181350 Leucine rich repeat containing 75A 17 16441577-16492153 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA028528 Uncertain Tissue enhanced 0 duodenum: 11.3;small intestine: 11.2 spleen: 5.6 -OFCC1 MRDS1 ENSG00000181355 Orofacial cleft 1 candidate 1 6 9596110-10211608 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035725, HPA050619 Uncertain Uncertain Nucleoplasm Tissue enriched 5 breast: 20.9 testis: 4.0 -OR5M8 ENSG00000181371 Olfactory receptor, family 5, subfamily M, member 8 11 56490435-56491370 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.1 -CCL13 CKb10, MCP-4, MGC17134, NCC-1, SCYA13, SCYL1 ENSG00000181374 Chemokine (C-C motif) ligand 13 17 34356452-34358610 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed lung: 31.6 -CCDC108 DKFZp434O0527, MGC35338 ENSG00000181378 Coiled-coil domain containing 108 2 219002846-219041527 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055156 Uncertain Group enriched 7 fallopian tube: 40.7;testis: 17.7 lung: 4.0 -DDX60L FLJ31033 ENSG00000181381 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 4 168356735-168537786 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043211, HPA055501 Approved Approved Plasma membrane
Cytosol Mixed bone marrow: 33.7 -SYNE4 C19orf46, DFNB76, FLJ36445, Nesp4, Nesprin-4 ENSG00000181392 Spectrin repeat containing, nuclear envelope family member 4 19 36003307-36008793 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060253 Uncertain Tissue enhanced 0 parathyroid gland: 18.3 prostate: 11.6 -OGFOD3 C17orf101, FLJ22222 ENSG00000181396 2-oxoglutarate and iron-dependent oxygenase domain containing 3 17 82389223-82418637 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052099 Uncertain Approved Nucleoplasm Expressed in all thyroid gland: 26.3 -WASH1 FAM39E, FLJ00038 ENSG00000181404 WAS protein family homolog 1 9 14521-29739 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002689 Uncertain Approved Vesicles Expressed in all epididymis: 23.6 -UTS2R GPR14 ENSG00000181408 Urotensin 2 receptor 17 82374230-82375586 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 1.1;thyroid gland: 1.3 duodenum: 0.3 -AATK AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77 ENSG00000181409 Apoptosis-associated tyrosine kinase 17 81117295-81166077 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009073 Supported Uncertain Mitochondria Tissue enhanced 0 cerebral cortex: 36.5;duodenum: 24.0 small intestine: 18.7 -DDN KIAA0749 ENSG00000181418 Dendrin 12 48995149-48999309 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060952 Uncertain Approved Nucleoplasm
Cytosol Group enriched 10 cerebral cortex: 96.3;skeletal muscle: 46.6 kidney: 6.9 -SAGE1 CT14, SAGE ENSG00000181433 Sarcoma antigen 1 X 135889205-135913061 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA003033, HPA003208 Supported Validated Nucleus Tissue enriched 57 testis: 8.9 cerebral cortex: 0.1 -ZNF467 EZI, Zfp467 ENSG00000181444 Zinc finger protein 467 7 149764182-149773479 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA042907 Uncertain Approved Mitochondria Mixed spleen: 14.4 -SOX2 ENSG00000181449 SRY (sex determining region Y)-box 2 3 181711924-181714436 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010648, HPA045725 Approved Supported Nucleoplasm Tissue enriched 8 cerebral cortex: 118.3 esophagus: 14.9 -ZNF678 MGC42493 ENSG00000181450 Zinc finger protein 678 1 227563543-227677443 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028507 Uncertain Approved Nucleoli
Mitochondria
Cytosol Mixed thyroid gland: 9.0 -TMEM45A DERP7, FLJ10134 ENSG00000181458 Transmembrane protein 45A 3 100492619-100577444 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA024082, HPA062101 Uncertain Approved Intermediate filaments
Microtubules Tissue enriched 10 skin: 563.8 placenta: 58.1 -RAP2B ENSG00000181467 RAP2B, member of RAS oncogene family 3 153162270-153167173 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed placenta: 19.2 -ZBTB2 bA351K16.2, KIAA1483, ZNF437 ENSG00000181472 Zinc finger and BTB domain containing 2 6 151364117-151391548 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023136, HPA023137, HPA023458, HPA023487 Approved Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 49.8 -RNF135 MGC13061 ENSG00000181481 Ring finger protein 135 17 30968785-30999911 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021576, HPA052404 Approved Approved Vesicles Expressed in all parathyroid gland: 28.1 -OR6T1 ENSG00000181499 Olfactory receptor, family 6, subfamily T, member 1 11 123942785-123943873 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA060893 Uncertain Not detected testis: 0.6 -ACBD4 FLJ13322 ENSG00000181513 Acyl-CoA binding domain containing 4 17 45132600-45144181 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051772 Approved Approved Nucleus
Vesicles Expressed in all duodenum: 31.2 -OR8D4 ENSG00000181518 Olfactory receptor, family 8, subfamily D, member 4 11 123906146-123907476 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -SGSH HSS, MPS3A, SFMD ENSG00000181523 N-sulfoglucosamine sulfohydrolase 17 80206716-80220923 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023436, HPA023451 Supported Expressed in all adrenal gland: 36.5 -MAB21L2 ENSG00000181541 Mab-21-like 2 (C. elegans) 4 150581922-150584693 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049324, HPA059864 Approved Nucleoplasm Tissue enhanced 0 colon: 18.7;smooth muscle: 26.1 small intestine: 12.6 -FANCB FAAP95, FAB, FLJ34064 ENSG00000181544 Fanconi anemia, complementation group B X 14843407-14873069 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003124 Uncertain Mixed bone marrow: 2.4 -EDDM3B FAM12B, HE3-BETA ENSG00000181552 Epididymal protein 3B 14 20768427-20770948 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001323 Supported Tissue enriched 233 epididymis: 3184.8 seminal vesicle: 13.6 -SETD2 FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A ENSG00000181555 SET domain containing 2 3 47016429-47163967 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042451 Approved Approved Nuclear speckles
Cytosol Expressed in all parathyroid gland: 30.5 -EDDM3A FAM12A, HE3-ALPHA ENSG00000181562 Epididymal protein 3A 14 20731699-20748380 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049952 Approved Tissue enriched 15 epididymis: 768.9 seminal vesicle: 50.1 -C6orf223 MGC45491 ENSG00000181577 Chromosome 6 open reading frame 223 6 44000580-44005958 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035765, HPA046117 Uncertain Uncertain Nucleoli fibrillar center Group enriched 10 breast: 22.3;lung: 5.6 duodenum: 1.4 -TMIE DFNB6 ENSG00000181585 Transmembrane inner ear 3 46701333-46710886 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA038298 Uncertain Uncertain Vesicles
Cytosol Tissue enhanced 0 adrenal gland: 7.5;cerebral cortex: 5.3 testis: 1.7 -MEX3D KIAA2031, OK/SW-cl.4, RKHD1, RNF193, Tino ENSG00000181588 Mex-3 RNA binding family member D 19 1554669-1568058 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065385 Approved Mixed testis: 17.7 -OR52D1 ENSG00000181609 Olfactory receptor, family 52, subfamily D, member 1 11 5488685-5489749 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046965 Uncertain Tissue enriched 6 testis: 2.3 epididymis: 0.3 -MRPS23 CGI-138, HSPC329, MRP-S23 ENSG00000181610 Mitochondrial ribosomal protein S23 17 57834781-57850056 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023453 Supported Supported Nuclear membrane
Mitochondria Expressed in all thyroid gland: 61.2 -OR52H1 ENSG00000181616 Olfactory receptor, family 52, subfamily H, member 1 11 5544561-5545523 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -FDCSP C4orf7, FDC-SP ENSG00000181617 Follicular dendritic cell secreted protein 4 70226071-70235252 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA014326, CAB014890 Supported Tissue enhanced 0 lymph node: 1027.1;salivary gland: 1383.1;tonsil: 2557.5 appendix: 372.9 -GPR135 HUMNPIIY20, PAFR ENSG00000181619 G protein-coupled receptor 135 14 59429022-59465342 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045337 Uncertain Tissue enhanced 0 testis: 9.1 fallopian tube: 5.0 -SLX1B GIYD2, MGC5178 ENSG00000181625 SLX1 homolog B, structure-specific endonuclease subunit 16 29454501-29458219 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047038 Uncertain Approved Nucleoplasm Mixed small intestine: 30.0 -ANKRD62 DKFZp779B1634 ENSG00000181626 Ankyrin repeat domain 62 18 12093853-12129749 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA059835 Supported Tissue enriched 11 testis: 4.1 pancreas: 0.3 -P2RY13 FKSG77, GPR86, GPR94, P2Y13 ENSG00000181631 Purinergic receptor P2Y, G-protein coupled, 13 3 151326312-151329548 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049047 Supported Tissue enhanced 0 spleen: 51.9 appendix: 28.7 -TNFSF15 MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A ENSG00000181634 Tumor necrosis factor (ligand) superfamily, member 15 9 114784635-114806126 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA012948, HPA046522 Approved Approved Nucleus
Nuclear membrane
Cytosol Mixed duodenum: 9.7 -ZFP41 FLJ00028, FLJ38705, ZNF753 ENSG00000181638 ZFP41 zinc finger protein 8 143246821-143262705 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA047232, HPA056268 Uncertain Uncertain Nucleus
Nucleoli
Plasma membrane Mixed cerebral cortex: 7.5 -PHLDA2 BWR1C, HLDA2, IPL, TSSC3 ENSG00000181649 Pleckstrin homology-like domain, family A, member 2 11 2928273-2929455 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003994 Uncertain Nucleoli Tissue enriched 8 placenta: 54.3 stomach: 6.8 -ATG9B APG9L2, FLJ14885, NOS3AS, SONE ENSG00000181652 Autophagy related 9B 7 151012209-151024499 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 esophagus: 1.5;placenta: 2.0;skin: 1.2 testis: 0.8 -GPR88 ENSG00000181656 G protein-coupled receptor 88 1 100538137-100542018 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA007488 Uncertain Approved Group enriched 12 breast: 9.7;cerebral cortex: 3.1;liver: 5.1;ovary: 3.4;parathyroid gland: 7.9;spleen: 14.7 adipose tissue: 0.6 -HKR1 ZNF875 ENSG00000181666 HKR1, GLI-Kruppel zinc finger family member 19 37312837-37369365 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA036126, HPA044855 Approved Supported Nucleoplasm
Golgi apparatus
Mitochondria Expressed in all thyroid gland: 54.4 -OR8K3 ENSG00000181689 Olfactory receptor, family 8, subfamily K, member 3 (gene/pseudogene) 11 56318307-56319245 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -PLAG1 ZNF912 ENSG00000181690 Pleiomorphic adenoma gene 1 8 56160904-56211324 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA072290 Approved Nuclear speckles Mixed ovary: 5.9 -OR8H1 ENSG00000181693 Olfactory receptor, family 8, subfamily H, member 1 11 56290053-56291090 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -OR5T1 OR5T1P ENSG00000181698 Olfactory receptor, family 5, subfamily T, member 1 11 56275639-56276619 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA050952 Uncertain Not detected adipose tissue: 0.0 -YIPF6 FinGER6, MGC21416 ENSG00000181704 Yip1 domain family, member 6 X 68498323-68537285 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003720 Uncertain Approved Vesicles Expressed in all thyroid gland: 32.7 -OR5T2 ENSG00000181718 Olfactory receptor, family 5, subfamily T, member 2 11 56232106-56233185 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -ZBTB20 DKFZp566F123, DPZF, ODA-8S, ZNF288 ENSG00000181722 Zinc finger and BTB domain containing 20 3 114338094-115147271 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015551, HPA016815 Approved Supported Nucleoplasm
Nuclear bodies Tissue enriched 5 testis: 20.9 ovary: 3.8 -OR2Z1 OR2Z2 ENSG00000181733 Olfactory receptor, family 2, subfamily Z, member 1 19 8730954-8732009 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA048760 Uncertain Not detected epididymis: 0.0 -C3orf58 DIA1, HASF, MGC33365 ENSG00000181744 Chromosome 3 open reading frame 58 3 143971798-144048719 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048992 Approved Mixed placenta: 53.5 -C5orf30 FLJ25291 ENSG00000181751 Chromosome 5 open reading frame 30 5 103258702-103278660 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043434 Uncertain Approved Nucleus
Mitochondria Mixed cerebral cortex: 31.4 -OR8K5 ENSG00000181752 Olfactory receptor, family 8, subfamily K, member 5 11 56159394-56160317 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -AMIGO1 AMIGO, KIAA1163 ENSG00000181754 Adhesion molecule with Ig-like domain 1 1 109504175-109509738 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046152 Approved Approved Nucleoplasm
Nuclear bodies Mixed parathyroid gland: 24.1 -OR8H3 ENSG00000181761 Olfactory receptor, family 8, subfamily H, member 3 11 56122373-56123311 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -OR8H2 ENSG00000181767 Olfactory receptor, family 8, subfamily H, member 2 11 56105018-56106055 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -GPR3 ACCA ENSG00000181773 G protein-coupled receptor 3 1 27392644-27395814 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB006254 Uncertain Tissue enhanced 0 cerebral cortex: 5.3 thyroid gland: 1.3 -TMEM252 C9orf71, MGC34760 ENSG00000181778 Transmembrane protein 252 9 68536580-68540867 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 kidney: 37.5;small intestine: 26.2 seminal vesicle: 15.4 -ODF3L2 C19orf19, FLJ40059 ENSG00000181781 Outer dense fiber of sperm tails 3-like 2 19 463346-474983 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA067973 Uncertain Group enriched 10 skeletal muscle: 2.7;testis: 7.6 spleen: 0.5 -OR5AS1 ENSG00000181785 Olfactory receptor, family 5, subfamily AS, member 1 11 56030419-56031393 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -ACTL9 MGC33407 ENSG00000181786 Actin-like 9 19 8697397-8698822 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA019231, HPA026693 Uncertain Tissue enriched 502 testis: 50.2 epididymis: 0.0 -SIAH2 ENSG00000181788 Siah E3 ubiquitin protein ligase 2 3 150741127-150763477 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA061293, CAB069930 Approved Supported Nucleoplasm
Vesicles Expressed in all adrenal gland: 95.8 -COPG1 COPG ENSG00000181789 Coatomer protein complex, subunit gamma 1 3 129249606-129277773 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037866, HPA037867, HPA045712 Supported Supported Nucleoplasm
Golgi apparatus
Cytosol Expressed in all epididymis: 188.8 -ADGRB1 BAI1 ENSG00000181790 Adhesion G protein-coupled receptor B1 8 142449430-142545009 Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 9 cerebral cortex: 22.0 spleen: 2.3 -OR6S1 OR6S1Q ENSG00000181803 Olfactory receptor, family 6, subfamily S, member 1 14 20640696-20641691 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -SLC9A9 FLJ35613, NHE9 ENSG00000181804 Solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 3 143265222-143848531 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058234 Approved Mixed placenta: 22.1 -LSM10 MGC15749 ENSG00000181817 LSM10, U7 small nuclear RNA associated 1 36391238-36397892 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA048469 Supported Nucleus
Nuclear bodies Expressed in all lymph node: 61.3 -RELL1 ENSG00000181826 RELT-like 1 4 37590800-37686376 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013377 Approved Supported Plasma membrane
Microtubules Mixed thyroid gland: 27.6 -RFX7 FLJ12994, RFXDC2 ENSG00000181827 Regulatory factor X, 7 15 56087280-56243266 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035462 Supported Approved Nucleus
Nuclear membrane Mixed testis: 8.3 -SLC35C1 FLJ11320, FUCT1 ENSG00000181830 Solute carrier family 35 (GDP-fucose transporter), member C1 11 45804072-45813015 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA064001 Supported Supported Golgi apparatus Expressed in all esophagus: 29.5 -TIGIT DKFZp667A205, FLJ39873, VSIG9, VSTM3 ENSG00000181847 T cell immunoreceptor with Ig and ITIM domains 3 114276913-114310288 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 45.0 spleen: 21.0 -RNF41 NRDP1, SBBI03 ENSG00000181852 Ring finger protein 41, E3 ubiquitin protein ligase 12 56202175-56221933 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016812 Approved Approved Nucleus
Nuclear bodies
Midbody ring Expressed in all cerebral cortex: 54.8 -SLC2A4 GLUT4 ENSG00000181856 Solute carrier family 2 (facilitated glucose transporter), member 4 17 7281667-7288257 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016544 Supported Tissue enhanced 0 heart muscle: 30.1;skeletal muscle: 45.0 adipose tissue: 21.9 -FTMT MtF ENSG00000181867 Ferritin mitochondrial 5 121851955-121852833 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 420 testis: 47.1 cervix: 0.1 -IBA57 C1orf69, FLJ12734 ENSG00000181873 IBA57 homolog, iron-sulfur cluster assembly 1 228165815-228182257 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030555, HPA030556, HPA030557 Approved Supported Mitochondria Mixed parathyroid gland: 4.2 -CLDN7 CEPTRL2, CPETRL2, Hs.84359 ENSG00000181885 Claudin 7 17 7259903-7263983 Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013063, HPA014703, HPA073662 Supported Approved Vesicles
Cell Junctions Mixed small intestine: 357.1 -ZNF329 FLJ12586 ENSG00000181894 Zinc finger protein 329 19 58126252-58155110 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA044373 Uncertain Approved Nucleoplasm
Nuclear membrane Mixed parathyroid gland: 16.3 -ZNF101 DKFZp570I0164, HZF12 ENSG00000181896 Zinc finger protein 101 19 19668796-19683509 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023449, HPA055486 Uncertain Tissue enhanced 0 lymph node: 31.9 tonsil: 23.3 -OR4C6 ENSG00000181903 Olfactory receptor, family 4, subfamily C, member 6 11 55665167-55666096 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected tonsil: 0.1 -C5orf24 FLJ37562 ENSG00000181904 Chromosome 5 open reading frame 24 5 134845680-134859737 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057749, HPA062502 Uncertain Supported Nucleus Expressed in all thyroid gland: 49.6 -ADO C10orf22, FLJ14547 ENSG00000181915 2-aminoethanethiol (cysteamine) dioxygenase 10 62804857-62808483 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039194, HPA040437 Approved Expressed in all testis: 70.2 -COA4 CHCHD8, CMC3, E2IG2 ENSG00000181924 Cytochrome c oxidase assembly factor 4 homolog 11 73872667-73876988 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040126 Approved Approved Nucleus
Nucleoli fibrillar center
Mitochondria Expressed in all adrenal gland: 81.8 -OR4P4 OR4P3P ENSG00000181927 Olfactory receptor, family 4, subfamily P, member 4 11 55638358-55639296 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence No evidence Evidence at protein level HPA059458 Uncertain Not detected adipose tissue: 0.0 -PRKAG1 ENSG00000181929 Protein kinase, AMP-activated, gamma 1 non-catalytic subunit 12 49002274-49019197 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077805 Approved Nucleoplasm
Cytosol Expressed in all breast: 57.0 -OR4C16 ENSG00000181935 Olfactory receptor, family 4, subfamily C, member 16 (gene/pseudogene) 11 55572128-55573060 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins No evidence No evidence No evidence HPA059128 Uncertain Not detected epididymis: 0.0 -GINS3 FLJ13912, PSF3 ENSG00000181938 GINS complex subunit 3 (Psf3 homolog) 16 58295080-58406144 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041216, HPA048209 Uncertain Validated Nucleoplasm Mixed testis: 10.3 -OR4C15 ENSG00000181939 Olfactory receptor, family 4, subfamily C, member 15 11 55554307-55555419 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA061939 Uncertain Not detected adipose tissue: 0.0 -OR4A15 ENSG00000181958 Olfactory receptor, family 4, subfamily A, member 15 11 55367884-55368918 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence No evidence Evidence at protein level Not detected adipose tissue: 0.0 -OR4A16 OR4A16Q ENSG00000181961 Olfactory receptor, family 4, subfamily A, member 16 11 55343201-55344187 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.1 -OR52K2 ENSG00000181963 Olfactory receptor, family 52, subfamily K, member 2 11 4449295-4450361 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected bone marrow: 0.1 -NEUROG1 AKA, bHLHa6, Math4C, NEUROD3, ngn1 ENSG00000181965 Neurogenin 1 5 135534282-135535949 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.0 -CCDC149 DKFZp761B107 ENSG00000181982 Coiled-coil domain containing 149 4 24806117-24980204 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044158, HPA047913 Uncertain Supported Nucleoli Expressed in all cerebral cortex: 24.1 -MRPS11 FLJ22512, FLJ23406, HCC-2 ENSG00000181991 Mitochondrial ribosomal protein S11 15 88467453-88480773 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043752, HPA050345 Supported Supported Mitochondria Expressed in all thyroid gland: 13.5 -SNRPE Sm-E ENSG00000182004 Small nuclear ribonucleoprotein polypeptide E 1 203861603-203870550 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all breast: 96.4 -RTKN2 bA531F24.1, Em:AC024597.2, FLJ39352, PLEKHK1 ENSG00000182010 Rhotekin 2 10 62183035-62268707 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037946, HPA038446 Uncertain Approved Nucleoplasm
Mitochondria Tissue enriched 8 lung: 121.4 testis: 14.7 -PNMAL1 FLJ10781, KIAA1183L ENSG00000182013 Paraneoplastic Ma antigen family-like 1 19 46466491-46471563 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012956 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Tissue enhanced 0 cerebral cortex: 134.3 testis: 42.5 -CHST15 BRAG, GALNAC4S-6ST, KIAA0598 ENSG00000182022 Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 10 124007666-124093607 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017584 Approved Approved Centrosome
Cytosol Expressed in all ovary: 45.4 -ADIG MGC39724, RP5-1100H13.2, SMAF1 ENSG00000182035 Adipogenin 20 38581195-38588463 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA041124 Uncertain Group enriched 10 epididymis: 5.0;testis: 16.0;thyroid gland: 3.4 seminal vesicle: 0.8 -USH1G ANKS4A, FLJ33924, Sans ENSG00000182040 Usher syndrome 1G (autosomal recessive) 17 74916084-74923256 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA024360 Uncertain Tissue enhanced 0 epididymis: 2.7;esophagus: 2.6 skin: 1.8 -MGAT4C HGNT-IV-H ENSG00000182050 MGAT4 family, member C 12 85955666-86838904 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 5 cerebral cortex: 11.9;epididymis: 13.6;testis: 11.1;thyroid gland: 31.8 adrenal gland: 3.3 -TRIM49B ENSG00000182053 Tripartite motif containing 49B 11 49027501-49038451 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.1 -IDH2 ENSG00000182054 Isocitrate dehydrogenase 2 (NADP+), mitochondrial 15 90083045-90102504 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007831 Supported Supported Mitochondria Expressed in all skeletal muscle: 450.2 -OR52A1 HPFH1OR ENSG00000182070 Olfactory receptor, family 52, subfamily A, member 1 11 5151009-5186382 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -PTCHD3 FLJ44037, PTR ENSG00000182077 Patched domain containing 3 10 27398187-27414368 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044613 Supported Tissue enriched 9 testis: 4.1 adipose tissue: 0.4 -OR6B2 OR6B2P ENSG00000182083 Olfactory receptor, family 6, subfamily B, member 2 2 240028965-240030456 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA047529 Uncertain Not detected testis: 0.6 -TMEM259 ASBABP1, C19orf6, MBRL, MGC4022 ENSG00000182087 Transmembrane protein 259 19 1009648-1021179 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042669, HPA054801 Approved Approved Nuclear speckles
Endoplasmic reticulum Expressed in all spleen: 132.3 -WRB CHD5, GET1 ENSG00000182093 Tryptophan rich basic protein 21 39380244-39428528 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018527 Approved Expressed in all fallopian tube: 107.8 -TNRC18 CAGL79, KIAA1856, TNRC18A ENSG00000182095 Trinucleotide repeat containing 18 7 5306790-5425414 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020730, HPA024251 Uncertain Supported Nucleoplasm
Nuclear membrane
Mitochondria
Cytosol Expressed in all parathyroid gland: 86.2 -FAM181B LOC220382, MGC33846 ENSG00000182103 Family with sequence similarity 181, member B 11 82729941-82733864 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA066861 Approved Approved Nuclear membrane
Mitochondria Tissue enriched 20 cerebral cortex: 17.5 fallopian tube: 0.8 -TMEM30B CDC50B ENSG00000182107 Transmembrane protein 30B 14 61277370-61281840 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043162 Uncertain Mixed parathyroid gland: 80.6 -DEXI MYLE ENSG00000182108 Dexi homolog (mouse) 16 10928891-10942460 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041511 Approved Approved Nuclear speckles
Cytosol Expressed in all skeletal muscle: 45.0 -ZNF716 FLJ46189 ENSG00000182111 Zinc finger protein 716 7 57450177-57473546 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 testis: 1.1 bone marrow: 0.1 -NOP10 MGC70651, NOLA3, NOP10P ENSG00000182117 NOP10 ribonucleoprotein 15 34341713-34343177 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059198 Supported Supported Nuclear bodies Expressed in all epididymis: 284.1 -FAM89A C1orf153, MGC15887 ENSG00000182118 Family with sequence similarity 89, member A 1 231018958-231040246 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059052, HPA059578 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all placenta: 97.9 -KCNIP1 KCHIP1 ENSG00000182132 Kv channel interacting protein 1 5 170353487-170736632 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022864, HPA066717 Uncertain Uncertain Vesicles Tissue enhanced 0 cerebral cortex: 40.6;epididymis: 26.0 seminal vesicle: 7.8 -TDRKH TDRD2 ENSG00000182134 Tudor and KH domain containing 1 151770107-151791416 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016419, HPA019625 Approved Approved Centrosome
Cytosol Tissue enhanced 0 parathyroid gland: 75.8;testis: 40.7 cerebral cortex: 13.0 -ZNF708 KOX8, ZNF15, ZNF15L1 ENSG00000182141 Zinc finger protein 708 19 21221500-21329425 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed cerebral cortex: 17.8 -IST1 KIAA0174 ENSG00000182149 Increased sodium tolerance 1 homolog (yeast) 16 71845996-71931199 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041802, HPA054532 Approved Supported Vesicles Expressed in all parathyroid gland: 174.9 -ERCC6L2 C9orf102, FLJ37706, RAD26L ENSG00000182150 Excision repair cross-complementation group 6-like 2 9 95875701-96014571 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021260 Uncertain Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 27.0 -MRPL41 BMRP, MRP-L27, MRPL27, PIG3, RPML27 ENSG00000182154 Mitochondrial ribosomal protein L41 9 137551199-137552555 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024550, HPA027160 Supported Supported Mitochondria Expressed in all skeletal muscle: 59.8 -ENPP7 alk-SMase, NPP7 ENSG00000182156 Ectonucleotide pyrophosphatase/phosphodiesterase 7 17 79730919-79742222 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024603 Approved Group enriched 22 duodenum: 46.9;small intestine: 112.8 kidney: 3.5 -CREB3L2 BBF2H7, TCAG_1951439 ENSG00000182158 CAMP responsive element binding protein 3-like 2 7 137874979-138002067 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015068, HPA015534 Uncertain Supported Nucleoplasm
Endoplasmic reticulum Expressed in all thyroid gland: 109.9 -P2RY8 P2Y8 ENSG00000182162 Purinergic receptor P2Y, G-protein coupled, 8 X 1462572-1537107 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003631 Supported Tissue enhanced 0 lymph node: 43.1 tonsil: 29.0 -UNC5C ENSG00000182168 Unc-5 netrin receptor C 4 95162504-95549206 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 thyroid gland: 19.9 adrenal gland: 11.7 -MRGPRG GPR169, mrgG ENSG00000182170 MAS-related GPR, member G 11 3217944-3218813 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058909 Uncertain Tissue enriched 18 testis: 1.7 adipose tissue: 0.0 -TSEN54 SEN54, SEN54L ENSG00000182173 TSEN54 tRNA splicing endonuclease subunit 17 75516060-75524739 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053097 Uncertain Expressed in all skin: 20.4 -RGMA RGM, RGMa ENSG00000182175 Repulsive guidance molecule family member a 15 93035273-93089204 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012343, HPA039880, HPA044222 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 116.9;smooth muscle: 83.8 skeletal muscle: 42.6 -ASB18 ENSG00000182177 Ankyrin repeat and SOCS box containing 18 2 236194872-236264409 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA068447 Approved Group enriched 7 heart muscle: 3.9;skeletal muscle: 3.6;testis: 1.0 cerebral cortex: 0.4 -UBA7 D8, UBA1B, UBE1L, UBE2 ENSG00000182179 Ubiquitin-like modifier activating enzyme 7 3 49805207-49813946 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015444, HPA058182 Approved Approved Nucleoplasm
Vesicles
Cytosol Expressed in all spleen: 66.5 -MRPS16 CGI-132 ENSG00000182180 Mitochondrial ribosomal protein S16 10 73248843-73252693 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050081, HPA054538 Supported Supported Mitochondria
Cytosol Expressed in all cerebral cortex: 30.5 -FAM159A MGC52498 ENSG00000182183 Family with sequence similarity 159, member A 1 52633344-52669683 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030744 Uncertain Tissue enhanced 0 lymph node: 8.9;tonsil: 6.9 spleen: 4.6 -RAD51B hREC2, R51H2, RAD51L1, REC2 ENSG00000182185 RAD51 paralog B 14 67819779-68730218 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016191, HPA051869 Supported Approved Nucleoplasm
Nuclear bodies Mixed epididymis: 11.3 -CRYGB CRYG2 ENSG00000182187 Crystallin, gamma B 2 208142573-208146168 Disease related genes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected testis: 0.6 -LDOC1 BCUR1, Mar7, Mart7 ENSG00000182195 Leucine zipper, down-regulated in cancer 1 X 141175745-141177125 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051768, HPA061842 Approved Supported Nucleus
Nucleoli Mixed cerebral cortex: 73.2 -ARL6IP4 SFRS20, SR-25, SRp25, SRrp37 ENSG00000182196 ADP-ribosylation factor-like 6 interacting protein 4 12 122980060-122982913 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052098 Approved Expressed in all adrenal gland: 186.8 -EXT1 LGCR, LGS, ttv ENSG00000182197 Exostosin glycosyltransferase 1 8 117794490-118111853 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044394 Uncertain Expressed in all duodenum: 32.5 -SHMT2 SHMT ENSG00000182199 Serine hydroxymethyltransferase 2 (mitochondrial) 12 57229327-57234935 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020543, HPA020549 Supported Validated Microtubules
Mitochondria Expressed in all liver: 74.8 -MOB2 HCCA2 ENSG00000182208 MOB kinase activator 2 11 1469457-1501247 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046313 Uncertain Supported Nucleus
Nucleoli
Cytosol Expressed in all seminal vesicle: 35.2 -HHIPL1 KIAA1822 ENSG00000182218 HHIP-like 1 14 99645110-99680569 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052767 Approved Tissue enhanced 0 cerebral cortex: 6.6 smooth muscle: 2.6 -ATP6AP2 APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR ENSG00000182220 ATPase, H+ transporting, lysosomal accessory protein 2 X 40580908-40606637 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003156 Approved Expressed in all parathyroid gland: 899.3 -ZAR1 Z3CXXC6 ENSG00000182223 Zygote arrest 1 4 48490252-48494389 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 1.1 bone marrow: 0.2 -CYB5D1 FLJ32499 ENSG00000182224 Cytochrome b5 domain containing 1 17 7857746-7862282 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA021632 Uncertain Approved Nucleoli
Golgi apparatus Expressed in all fallopian tube: 42.0 -FAM153B ENSG00000182230 Family with sequence similarity 153, member B 5 176060689-176132258 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042585, HPA044022, HPA046691, HPA052337, HPA055498 Uncertain Tissue enhanced 0 ovary: 8.3;testis: 14.6 cerebral cortex: 4.1 -BACE2 AEPLC, ALP56, CEAP1, DRAP ENSG00000182240 Beta-site APP-cleaving enzyme 2 21 41167801-41282518 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB008975 Uncertain Mixed stomach: 31.1 -UBE2E2 FLJ25157, UbcH8 ENSG00000182247 Ubiquitin-conjugating enzyme E2E 2 3 23203020-23591793 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003303, HPA028872, HPA030445, CAB073417 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 40.2 -SYNM DMN, KIAA0353, SYN ENSG00000182253 Synemin, intermediate filament protein 15 99098217-99135593 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017192, HPA040066, HPA044200, HPA077856 Supported Supported Intermediate filaments Tissue enhanced 0 seminal vesicle: 400.4 smooth muscle: 225.2 -KCNA4 HK1, HPCN2, KCNA4L, Kv1.4 ENSG00000182255 Potassium channel, voltage gated shaker related subfamily A, member 4 11 30009741-30017023 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB001977, HPA016422 Approved Tissue enhanced 0 adrenal gland: 7.9;cerebral cortex: 4.3 heart muscle: 1.2 -GABRG3 ENSG00000182256 Gamma-aminobutyric acid (GABA) A receptor, gamma 3 15 26971282-27541991 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA054010 Supported Tissue enhanced 0 prostate: 10.6;testis: 16.4 cerebral cortex: 4.2 -PRR34 C22orf26, FLJ10945 ENSG00000182257 Proline rich 34 22 46049478-46054144 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed epididymis: 1.7 -NLRP10 CLR11.1, NALP10, NOD8, PAN5, Pynod ENSG00000182261 NLR family, pyrin domain containing 10 11 7959424-7965426 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039498, HPA040101 Uncertain Approved Nucleoplasm
Nuclear membrane Tissue enriched 7 skin: 3.2 epididymis: 0.4 -FIGN ENSG00000182263 Fidgetin 2 163593396-163736012 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034987, HPA057919 Approved Approved Nucleoplasm
Vesicles
Plasma membrane
Cell Junctions
Cytosol Mixed ovary: 5.1 -IZUMO1 IZUMO, MGC34799, OBF ENSG00000182264 Izumo sperm-egg fusion 1 19 48740852-48746909 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038104 Supported Tissue enriched 22 testis: 19.2 lung: 0.8 -TMIGD1 TMIGD, UNQ9372 ENSG00000182271 Transmembrane and immunoglobulin domain containing 1 17 30316333-30334059 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA021946 Approved Mitochondria Group enriched 24 colon: 83.2;rectum: 111.5;small intestine: 165.6 kidney: 5.0 -B4GALNT4 FLJ25045, NGalNAc-T1 ENSG00000182272 Beta-1,4-N-acetyl-galactosaminyl transferase 4 11 369796-382116 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053126 Uncertain Approved Nucleoplasm
Microtubules
Cytokinetic bridge
Mitotic spindle Tissue enhanced 0 cerebral cortex: 30.9;ovary: 11.7 endometrium: 6.9 -AP1S2 MRX59, MRXS5, PGS, SIGMA1B ENSG00000182287 Adaptor-related protein complex 1, sigma 2 subunit X 15825806-15855014 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049894, HPA060945 Uncertain Supported Golgi apparatus
Vesicles Tissue enriched 7 epididymis: 906.3 smooth muscle: 125.6 -C8orf33 FLJ20989 ENSG00000182307 Chromosome 8 open reading frame 33 8 145052378-145056030 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024812, HPA026104 Approved Uncertain Nucleoplasm
Plasma membrane Expressed in all parathyroid gland: 25.8 -DCAF4L1 WDR21B ENSG00000182308 DDB1 and CUL4 associated factor 4-like 1 4 41981696-41986467 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB073535 Supported Tissue enriched 122 testis: 45.7 skin: 0.3 -MBD3L3 ENSG00000182315 Methyl-CpG binding domain protein 3-like 3 19 7056209-7058640 Predicted intracellular proteins No evidence No evidence No evidence HPA051259 Uncertain Not detected testis: 0.3 -ZSCAN22 HKR2, ZNF50 ENSG00000182318 Zinc finger and SCAN domain containing 22 19 58327019-58342332 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006471 Uncertain Approved Plasma membrane
Actin filaments
Cytosol Mixed parathyroid gland: 3.6 -KCNJ14 IRK4, Kir2.4 ENSG00000182324 Potassium channel, inwardly rectifying subfamily J, member 14 19 48455509-48466980 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071765 Approved Nucleoli Mixed testis: 2.9 -FBXL6 FBL6 ENSG00000182325 F-box and leucine-rich repeat protein 6 8 144355431-144359376 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA008867 Approved Nucleus Mixed duodenum: 9.2 -C1S ENSG00000182326 Complement component 1, s subcomponent 12 6988259-7071032 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016722, HPA018852 Supported Approved Nucleus
Cytosol Expressed in all liver: 1327.2 -GLTPD2 ENSG00000182327 Glycolipid transfer protein domain containing 2 17 4788959-4790390 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058295, HPA065267 Uncertain Approved Vesicles Tissue enhanced 0 duodenum: 11.3;kidney: 12.9;liver: 14.0 small intestine: 7.4 -KIAA2012 ENSG00000182329 KIAA2012 2 202073255-202197862 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12 fallopian tube: 8.5 testis: 0.6 -PRAMEF8 ENSG00000182330 PRAME family member 8 1 13281035-13285174 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA049887, HPA051704 Uncertain Not detected epididymis: 0.0 -LIPF HGL, HLAL ENSG00000182333 Lipase, gastric 10 88664441-88678814 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045930 Supported Tissue enriched 82 stomach: 21780.0 duodenum: 267.0 -OR5P3 JCG1 ENSG00000182334 Olfactory receptor, family 5, subfamily P, member 3 11 7825037-7825972 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA060787 Uncertain Not detected epididymis: 0.1 -DAOA G72 ENSG00000182346 D-amino acid oxidase activator 13 105465867-105491034 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA053114 Approved Not detected epididymis: 0.0 -ZNF804B FLJ32110 ENSG00000182348 Zinc finger protein 804B 7 88759368-89337057 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026702 Uncertain Tissue enriched 7 thyroid gland: 7.3 kidney: 0.9 -KBTBD3 BKLHD3 ENSG00000182359 Kelch repeat and BTB (POZ) domain containing 3 11 106051098-106077765 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047385 Uncertain Mixed cerebral cortex: 7.7 -YBEY C21orf57 ENSG00000182362 YbeY metallopeptidase (putative) 21 46286337-46297751 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016593, HPA018162 Uncertain Validated Nucleoplasm Expressed in all testis: 91.6 -CLN8 C8orf61, EPMR, FLJ39417 ENSG00000182372 Ceroid-lipofuscinosis, neuronal 8 8 1755778-1786572 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all placenta: 10.8 -PLCXD1 FLJ11323 ENSG00000182378 Phosphatidylinositol-specific phospholipase C, X domain containing 1 X 276322-303356 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA007721 Approved Approved Cytosol Expressed in all stomach: 26.3 -NXPH4 NPH4 ENSG00000182379 Neurexophilin 4 12 57216795-57226449 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 8.3;prostate: 6.7;skin: 12.2 placenta: 3.8 -CACNB4 EJM4 ENSG00000182389 Calcium channel, voltage-dependent, beta 4 subunit 2 151832776-152099079 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015601 Approved Tissue enhanced 0 cerebral cortex: 34.8 skin: 11.2 -IFNL1 IL-29, IL29 ENSG00000182393 Interferon, lambda 1 19 39296325-39298673 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.1 -TRAPPC6B ENSG00000182400 Trafficking protein particle complex 6B 14 39147811-39170532 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047928 Uncertain Approved Endoplasmic reticulum Expressed in all cerebral cortex: 45.9 -PGBD4 FLJ32638, FLJ37497 ENSG00000182405 PiggyBac transposable element derived 4 15 34102073-34108684 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA040896, HPA059823 Uncertain Approved Nucleoplasm
Centrosome Mixed testis: 3.6 -CDY2A CDY2 ENSG00000182415 Chromodomain protein, Y-linked, 2A Y 18025787-18028597 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 24 epididymis: 1.3;testis: 3.5 parathyroid gland: 0.0 -NPLOC4 FLJ20657, KIAA1499, NPL4 ENSG00000182446 NPL4 homolog, ubiquitin recognition factor 17 81556887-81648465 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021560, HPA023295 Supported Supported Nucleoplasm
Cytosol Expressed in all testis: 67.9 -OTOL1 C1QTNF15 ENSG00000182447 Otolin 1 3 161496808-161503942 Predicted secreted proteins No evidence No evidence No evidence HPA041030 Uncertain Not detected cerebral cortex: 0.8 -KCNK4 K2p4.1, TRAAK ENSG00000182450 Potassium channel, two pore domain subfamily K, member 4 11 64291302-64300031 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 12 cerebral cortex: 4.3 cervix: 0.3 -TEX19 FLJ35767 ENSG00000182459 Testis expressed 19 17 82359247-82363776 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA054577 Supported Tissue enriched 265 testis: 27.2 cerebral cortex: 0.1 -TSHZ2 C20orf17, OVC10-2, TSH2, ZABC2, ZNF218 ENSG00000182463 Teashirt zinc finger homeobox 2 20 52972407-53495330 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038123 Uncertain Approved Nucleoplasm
Golgi apparatus Mixed ovary: 21.7 -CAPN12 ENSG00000182472 Calpain 12 19 38730187-38769904 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043492, HPA053322 Uncertain Approved Nucleoplasm
Focal adhesion sites Tissue enriched 7 gallbladder: 35.0 cervix: 4.7 -EXOC7 EXO70, Exo70p, KIAA1067, YJL085W ENSG00000182473 Exocyst complex component 7 17 76081017-76121576 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022840, HPA022842 Supported Approved Vesicles
Plasma membrane
Cytosol Expressed in all parathyroid gland: 100.5 -KPNA2 IPOA1, QIP2, RCH1, SRP1alpha ENSG00000182481 Karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 17 68035519-68046842 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015460, HPA041270 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 347.6 -XKRX XKR2, XPLAC ENSG00000182489 XK, Kell blood group complex subunit-related, X-linked X 100913445-100929433 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 9.5 tonsil: 3.3 -BGN DSPG1, SLRR1A ENSG00000182492 Biglycan X 153494939-153509554 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003157, CAB003678 Supported Approved Endoplasmic reticulum
Golgi apparatus Mixed gallbladder: 503.2 -CEP97 FLJ23047, LRRIQ2 ENSG00000182504 Centrosomal protein 97kDa 3 101723925-101770562 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002980 Approved Supported Microtubule organizing center
Cytosol Mixed testis: 13.4 -LHFPL1 ENSG00000182508 Lipoma HMGIC fusion partner-like 1 X 112630648-112680054 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003029 Uncertain Tissue enhanced 0 cerebral cortex: 1.8 seminal vesicle: 1.3 -FES FPS ENSG00000182511 FES proto-oncogene, tyrosine kinase 15 90883695-90895776 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001376 Approved Approved Nucleus
Vesicles
Cytosol Expressed in all spleen: 98.1 -GLRX5 C14orf87, GRX5, PR01238 ENSG00000182512 Glutaredoxin 5 14 95533503-95544724 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042465, HPA063716 Approved Supported Mitochondria Expressed in all bone marrow: 56.7 -FAM104B CXorf44, FLJ20434 ENSG00000182518 Family with sequence similarity 104, member B X 55143102-55161310 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA049082 Approved Expressed in all fallopian tube: 73.7 -TBPL2 TBP2, TRF3 ENSG00000182521 TATA box binding protein like 2 14 55413541-55456726 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056241 Uncertain Mixed testis: 2.1 -CAV3 LGMD1C, LQT9, VIP-21, VIP21 ENSG00000182533 Caveolin 3 3 8733800-8841808 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017518, CAB018557, HPA054488 Supported Supported Vesicles
Plasma membrane Group enriched 6 heart muscle: 13.0;skeletal muscle: 63.3 esophagus: 6.0 -MXRA7 FLJ46603, PS1TP1, TMAP1 ENSG00000182534 Matrix-remodelling associated 7 17 76672551-76711016 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044819 Uncertain Approved Nucleus
Endoplasmic reticulum Expressed in all thyroid gland: 454.2 -LIMK2 ENSG00000182541 LIM domain kinase 2 22 31212239-31280080 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008183, CAB019313, HPA053882 Approved Supported Nucleoplasm
Cytosol Expressed in all skin: 71.0 -MFSD5 MGC11308 ENSG00000182544 Major facilitator superfamily domain containing 5 12 53251251-53254405 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039773 Uncertain Expressed in all skin: 49.7 -RNASE10 RAH1, RNASE9 ENSG00000182545 Ribonuclease, RNase A family, 10 (non-active) 14 20505537-20511169 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052593 Uncertain Mixed testis: 4.1 -ADI1 APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL ENSG00000182551 Acireductone dioxygenase 1 2 3497361-3519736 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035403, HPA035404 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all liver: 228.6 -RWDD4 FAM28A, MGC10198, RWDD4A ENSG00000182552 RWD domain containing 4 4 183639635-183659225 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036501, HPA036502 Approved Approved Intermediate filaments Expressed in all adrenal gland: 68.5 -SPNS3 MGC29671 ENSG00000182557 Spinster homolog 3 (Drosophila) 17 4433688-4488208 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023928 Uncertain Tissue enriched 6 bone marrow: 12.4 spleen: 2.1 -CLEC4G LSECtin, UNQ431 ENSG00000182566 C-type lectin domain family 4, member G 19 7728957-7733906 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003789, HPA014044 Supported Group enriched 6 adipose tissue: 18.5;liver: 27.6;lymph node: 17.0 urinary bladder: 3.5 -SATB1 ENSG00000182568 SATB homeobox 1 3 18345387-18445588 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051769, CAB056144 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 75.1 -NXPH3 NPH3 ENSG00000182575 Neurexophilin 3 17 49575858-49583827 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 15.6 seminal vesicle: 9.5 -CSF1R C-FMS, CD115, CSFR, FMS ENSG00000182578 Colony stimulating factor 1 receptor 5 150053291-150113372 Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008970, HPA012323 Uncertain Supported Vesicles
Plasma membrane Mixed spleen: 150.2 -EPHB3 ETK2, Hek2, Tyro6 ENSG00000182580 EPH receptor B3 3 184561784-184582409 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007698, HPA008184, CAB034350 Approved Tissue enhanced 0 skin: 45.4 stomach: 17.9 -VCX VCX-10r, VCX-B1, VCX1, VCX10R ENSG00000182583 Variable charge, X-linked X 7842262-7844143 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044996, HPA049357 Supported Tissue enriched 155 testis: 39.2 duodenum: 0.2 -ACTL10 C20orf134 ENSG00000182584 Actin-like 10 20 33666498-33668525 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 16 testis: 22.2 prostate: 1.4 -EPGN ALGV3072, EPG, epigen, PRO9904 ENSG00000182585 Epithelial mitogen 4 74308473-74315307 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014369 Approved Nucleus
Nuclear membrane
Cytosol Tissue enriched 12 esophagus: 63.9 seminal vesicle: 5.3 -KRTAP11-1 KAP11.1 ENSG00000182591 Keratin associated protein 11-1 21 30880644-30881555 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA054008 Supported Not detected skin: 0.1 -C2orf82 ASCL830, UNQ830 ENSG00000182600 Chromosome 2 open reading frame 82 2 232857270-232878708 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052824 Uncertain Approved Nucleus
Nucleoli Tissue enhanced 0 breast: 5.2;testis: 4.1 cerebral cortex: 2.6 -HS3ST4 3OST4 ENSG00000182601 Heparan sulfate (glucosamine) 3-O-sulfotransferase 4 16 25692026-26137688 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 7 cerebral cortex: 18.7 breast: 2.7 -TRAK1 KIAA1042, MILT1, OIP106 ENSG00000182606 Trafficking protein, kinesin binding 1 3 42013802-42225889 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005853, HPA011367 Approved Approved Nucleoplasm
Endoplasmic reticulum Expressed in all heart muscle: 111.9 -TSPAN10 OCSP ENSG00000182612 Tetraspanin 10 17 81637171-81648749 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 1.5 lymph node: 1.0 -OR2V2 OR2V3, OST713 ENSG00000182613 Olfactory receptor, family 2, subfamily V, member 2 5 181154943-181155890 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA049953 Uncertain Not detected fallopian tube: 0.4 -PLCB1 KIAA0581, PLC-I, PLC154 ENSG00000182621 Phospholipase C, beta 1 (phosphoinositide-specific) 20 8114453-8968360 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004275, CAB005334, HPA034743, HPA057910 Supported Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 66.1;parathyroid gland: 110.6 placenta: 23.5 -SKA2 FAM33A, FLJ12758 ENSG00000182628 Spindle and kinetochore associated complex subunit 2 17 59109951-59155269 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059235 Uncertain Expressed in all cerebral cortex: 43.1 -RXFP3 GPCR135, RLN3R1, RXFPR3, SALPR ENSG00000182631 Relaxin/insulin-like family peptide receptor 3 5 33936386-33938237 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level HPA027833 Uncertain Not detected adrenal gland: 0.3 -OR10G7 ENSG00000182634 Olfactory receptor, family 10, subfamily G, member 7 11 124038066-124039010 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected rectum: 0.1 -NDN HsT16328, PWCR ENSG00000182636 Necdin, melanoma antigen (MAGE) family member 15 23685400-23687330 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA074457 Approved Nucleoplasm
Cytosol Mixed ovary: 84.9 -CCDC172 C10orf96, MGC35062 ENSG00000182645 Coiled-coil domain containing 172 10 116324428-116380029 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 15 testis: 22.1 prostate: 1.4 -OR4Q3 C14orf13, OR4Q4 ENSG00000182652 Olfactory receptor, family 4, subfamily Q, member 3 14 19747428-19748369 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA049924 Uncertain Tissue enriched 20 testis: 2.7 cerebral cortex: 0.1 -NTM HNT, IGLON2, NTRI ENSG00000182667 Neurotrimin 11 131370478-132336822 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB024875 Supported Tissue enhanced 0 cerebral cortex: 116.3 lung: 39.1 -TTC3 DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII ENSG00000182670 Tetratricopeptide repeat domain 3 21 37073226-37203112 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016810, HPA023964, HPA036304 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all thyroid gland: 107.0 -KCNB2 Kv2.2 ENSG00000182674 Potassium channel, voltage gated Shab related subfamily B, member 2 8 72537391-72938349 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA065970 Approved Nucleoli
Plasma membrane
Midbody Tissue enhanced 0 cerebral cortex: 3.2;spleen: 3.4 testis: 0.7 -PPP1R27 DYSFIP1, toonin ENSG00000182676 Protein phosphatase 1, regulatory subunit 27 17 81833492-81835050 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048632 Uncertain Tissue enriched 46 skeletal muscle: 171.0 prostate: 3.7 -BRICD5 C16orf79, MGC21830 ENSG00000182685 BRICHOS domain containing 5 16 2209253-2211950 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA019197, HPA063522 Uncertain Approved Nucleoplasm
Actin filaments Mixed testis: 10.6 -GALR2 GALNR2 ENSG00000182687 Galanin receptor 2 17 76074794-76077541 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA044513 Approved Tissue enhanced 0 smooth muscle: 2.4 bone marrow: 0.6 -RESP18 ENSG00000182698 Regulated endocrine-specific protein 18 2 219327409-219333177 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045849 Uncertain Tissue enhanced 0 cerebral cortex: 2.1 testis: 0.6 -IGIP C5orf53, LOC492311 ENSG00000182700 IgA-inducing protein 5 140125935-140129392 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA041877, HPA048615 Approved Approved Vesicles Mixed parathyroid gland: 28.1 -TSKU E2IG4, LRRC54, TSK ENSG00000182704 Tsukushi, small leucine rich proteoglycan 11 76782251-76798154 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA008164 Approved Approved Nucleus
Nuclear bodies Expressed in all liver: 114.5 -CMC4 MTCP1, MTCP1NB, p8, P8MTCP1 ENSG00000182712 C-x(9)-C motif containing 4 X 155061622-155071362 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045866 Approved Supported Mitochondria Expressed in all heart muscle: 20.7 -ANXA2 ANX2, ANX2L4, CAL1H, LIP2, LPC2D ENSG00000182718 Annexin A2 15 60347134-60402883 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004311 Approved Expressed in all esophagus: 1494.3 -RGS6 ENSG00000182732 Regulator of G-protein signaling 6 14 71932439-72566529 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003067 Uncertain Tissue enhanced 0 cerebral cortex: 17.5;testis: 18.6 thyroid gland: 8.7 -HOXB4 HOX2, HOX2F ENSG00000182742 Homeobox B4 17 48575513-48580111 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057432 Uncertain Approved Nucleus
Centrosome Tissue enhanced 0 epididymis: 15.9 fallopian tube: 12.4 -SLC35D3 FRCL1 ENSG00000182747 Solute carrier family 35, member D3 6 136922264-136925639 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030431, HPA067497 Uncertain Approved Microtubule organizing center Tissue enhanced 0 adrenal gland: 1.2 lung: 0.6 -PAQR7 MPRA, mSR ENSG00000182749 Progestin and adipoQ receptor family member VII 1 25861210-25871253 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046936 Approved Approved Cytosol Mixed testis: 51.0 -PAPPA ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1 ENSG00000182752 Pregnancy-associated plasma protein A, pappalysin 1 9 116153804-116402322 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001667, CAB016724 Supported Uncertain Plasma membrane
Cytosol Tissue enriched 7 placenta: 103.9 parathyroid gland: 14.6 -MAFA hMafA, RIPE3b1 ENSG00000182759 V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 8 143419182-143430406 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 11 skeletal muscle: 8.6;testis: 2.5 placenta: 0.5 -NGRN DSC92 ENSG00000182768 Neugrin, neurite outgrowth associated 15 90265659-90278141 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041367 Approved Mixed thyroid gland: 7.1 -GRID1 GluD1, KIAA1220 ENSG00000182771 Glutamate receptor, ionotropic, delta 1 10 85599555-86366493 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 7.7 thyroid gland: 3.4 -RPS17 MGC72007, RPS17L, RPS17L1, RPS17L2, S17 ENSG00000182774 Ribosomal protein S17 15 82536753-82540564 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA055060 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 1569.8 -HCAR2 GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG ENSG00000182782 Hydroxycarboxylic acid receptor 2 12 122701293-122703343 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA028660 Approved Approved Cell Junctions Tissue enhanced 0 spleen: 36.5 esophagus: 25.6 -OR2T29 ENSG00000182783 Olfactory receptor, family 2, subfamily T, member 29 1 248558544-248559491 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -CCDC87 FLJ10786 ENSG00000182791 Coiled-coil domain containing 87 11 66590176-66593083 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 testis: 18.2 parathyroid gland: 2.5 -GSTA5 ENSG00000182793 Glutathione S-transferase alpha 5 6 52831655-52870329 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004342, HPA048934, HPA053817 Uncertain Approved Cytosol Not detected testis: 0.2 -C1orf116 FLJ36507, MGC2742, MGC4309, SARG ENSG00000182795 Chromosome 1 open reading frame 116 1 207018521-207032756 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011888, HPA011889 Supported Supported Plasma membrane
Cytosol Tissue enhanced 0 esophagus: 112.9;lung: 109.5;prostate: 80.5 stomach: 54.8 -MAGEB17 ENSG00000182798 Melanoma antigen family B17 X 16167481-16171464 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA003756 Uncertain Tissue enriched 6 testis: 2.9 epididymis: 0.4 -CRIP2 CRP2, ESP1 ENSG00000182809 Cysteine-rich protein 2 14 105472962-105480170 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042664 Approved Approved Nucleus
Nucleoli
Plasma membrane Tissue enhanced 0 heart muscle: 343.0 fallopian tube: 114.8 -DDX28 FLJ11282, MDDX28 ENSG00000182810 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 16 68021274-68023442 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041911, HPA053585 Approved Supported Nucleoli
Mitochondria
Cytosol Expressed in all bone marrow: 11.2 -KRTAP13-2 KAP13-2 ENSG00000182816 Keratin associated protein 13-2 21 30348075-30425912 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 20 colon: 1.9;rectum: 2.0 epididymis: 0.0 -ACBD3 GCP60, GOCAP1, GOLPH1, PAP7 ENSG00000182827 Acyl-CoA binding domain containing 3 1 226144679-226186730 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015594 Uncertain Supported Golgi apparatus Expressed in all thyroid gland: 48.3 -C16orf72 FLJ41272, PRO0149 ENSG00000182831 Chromosome 16 open reading frame 72 16 9091648-9121640 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041568, HPA067492 Uncertain Approved Nucleoplasm
Vesicles Expressed in all bone marrow: 67.7 -PLCXD3 ENSG00000182836 Phosphatidylinositol-specific phospholipase C, X domain containing 3 5 41306954-41510628 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046849 Uncertain Approved Golgi apparatus Tissue enhanced 0 adrenal gland: 16.8;heart muscle: 21.1;ovary: 28.3 cerebral cortex: 8.3 -VMO1 ENSG00000182853 Vitelline membrane outer layer 1 homolog (chicken) 17 4785285-4786433 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023038 Uncertain Tissue enhanced 0 parathyroid gland: 34.1 spleen: 14.9 -OR4F15 ENSG00000182854 Olfactory receptor, family 4, subfamily F, member 15 15 101805720-101819147 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -ALG12 ECM39 ENSG00000182858 ALG12, alpha-1,6-mannosyltransferase 22 49900229-49918458 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003076, HPA051665 Approved Approved Endoplasmic reticulum Expressed in all thyroid gland: 17.1 -LCK ENSG00000182866 LCK proto-oncogene, Src family tyrosine kinase 1 32251239-32286165 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003494, CAB003816 Supported Approved Golgi apparatus Tissue enhanced 0 appendix: 68.8;lymph node: 127.7;tonsil: 75.1 spleen: 55.2 -GALNT9 GALNAC-T9 ENSG00000182870 Polypeptide N-acetylgalactosaminyltransferase 9 12 132196372-132329349 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA075016 Approved Vesicles Group enriched 7 cerebral cortex: 29.5;epididymis: 7.8;thyroid gland: 6.4 kidney: 1.9 -COL18A1 KNO, KNO1, KS ENSG00000182871 Collagen, type XVIII, alpha 1 21 45405137-45513720 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001961, HPA011025, HPA036104 Approved Approved Golgi apparatus Expressed in all cervix: 129.0 -RBM10 DXS8237E, GPATC9, GPATCH9, KIAA0122, ZRANB5 ENSG00000182872 RNA binding motif protein 10 X 47144869-47186813 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034972, HPA057372 Approved Validated Nuclear speckles Expressed in all ovary: 35.1 -ADGRG3 GPR97, Pb99, PGR26 ENSG00000182885 Adhesion G protein-coupled receptor G3 16 57668187-57689378 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040469 Uncertain Group enriched 5 appendix: 19.4;bone marrow: 86.7 adipose tissue: 9.6 -GLUD2 GLUDP1 ENSG00000182890 Glutamate dehydrogenase 2 X 121047588-121050080 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042492, HPA044839, HPA061369 Uncertain Supported Mitochondria Tissue enriched 11 testis: 46.3 epididymis: 4.0 -TMEM95 MGC129793, UNQ9390 ENSG00000182896 Transmembrane protein 95 17 7355123-7357219 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 48 testis: 9.9 gallbladder: 0.2 -TCHHL1 S100A17, THHL1 ENSG00000182898 Trichohyalin-like 1 1 152084144-152089064 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042579, HPA063483 Supported Approved Nuclear membrane
Nucleoli Not detected epididymis: 0.1 -RPL35A L35A ENSG00000182899 Ribosomal protein L35a 3 197949987-197956610 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 2038.5 -RGS7 ENSG00000182901 Regulator of G-protein signaling 7 1 240775514-241357230 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000688, CAB017561 Supported Approved Nucleus Group enriched 8 adrenal gland: 10.8;cerebral cortex: 47.0;testis: 13.4 stomach: 2.9 -SLC25A18 ENSG00000182902 Solute carrier family 25 (glutamate carrier), member 18 22 17563439-17590994 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 74.7;liver: 25.2 adipose tissue: 14.0 -ZNF721 KIAA1982 ENSG00000182903 Zinc finger protein 721 4 425815-499156 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA065313 Approved Microtubule organizing center
Cytosol Expressed in all cerebral cortex: 30.9 -TCEAL7 MGC23947, WEX5 ENSG00000182916 Transcription elongation factor A (SII)-like 7 X 103330196-103332326 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051507, HPA065080 Supported Supported Nucleus Tissue enhanced 0 cerebral cortex: 146.0 endometrium: 76.6 -C11orf54 PTD012 ENSG00000182919 Chromosome 11 open reading frame 54 11 93741591-93764749 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040088, HPA040511 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all kidney: 539.9 -CEP63 FLJ13386 ENSG00000182923 Centrosomal protein 63kDa 3 134485743-134575017 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058154, HPA058313 Approved Approved Nucleoplasm Expressed in all testis: 83.5 -WFDC10B WAP12 ENSG00000182931 WAP four-disulfide core domain 10B 20 45684653-45705019 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12 epididymis: 32.7 testis: 2.7 -SRPR Sralpha, SRP-alpha ENSG00000182934 Signal recognition particle receptor (docking protein) 11 126262919-126269144 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all epididymis: 167.7 -OTOP3 ENSG00000182938 Otopetrin 3 17 74935719-74949992 Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level HPA023498 Uncertain Not detected small intestine: 0.5 -EWSR1 EWS ENSG00000182944 EWS RNA-binding protein 1 22 29268009-29300525 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004230, HPA051771, HPA062953 Supported Validated Nucleus
Nucleoli Expressed in all testis: 213.0 -ODF3L1 MGC48986 ENSG00000182950 Outer dense fiber of sperm tails 3-like 1 15 75723977-75727688 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 testis: 24.0 gallbladder: 3.9 -HMGN4 HMG17L3, NHC ENSG00000182952 High mobility group nucleosomal binding domain 4 6 26538405-26546254 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077364 Uncertain Nucleus Expressed in all thyroid gland: 131.2 -SPATA13 ARHGEF29, FLJ31208 ENSG00000182957 Spermatogenesis associated 13 13 23979805-24307074 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040185, HPA041208 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 spleen: 91.5 lymph node: 27.5 -GJC1 CX45, GJA7 ENSG00000182963 Gap junction protein, gamma 1, 45kDa 17 44798448-44830816 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071788 Uncertain Nucleoli
Cell Junctions
Cytosol Tissue enhanced 0 endometrium: 43.9;placenta: 50.9;smooth muscle: 48.2 seminal vesicle: 27.0 -SOX1 ENSG00000182968 SRY (sex determining region Y)-box 1 13 112067647-112070488 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 8 cerebral cortex: 3.6;testis: 1.5 skin: 0.3 -CNOT10 FLJ12890, FLJ13165 ENSG00000182973 CCR4-NOT transcription complex, subunit 10 3 32685145-32773875 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035614, HPA041450 Approved Approved Nucleoplasm
Centrosome
Cytosol Expressed in all testis: 71.6 -RP11-294C11.1 ENSG00000182974 Olfactory receptor 4M2 15 21637909-21638992 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058889 Uncertain Tissue enriched 24 testis: 2.3 epididymis: 0.0 -MTA1 ENSG00000182979 Metastasis associated 1 14 105419820-105470729 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004508, HPA005544 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 35.8 -ZNF662 FLJ45880 ENSG00000182983 Zinc finger protein 662 3 42905731-42917641 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039116, HPA040377 Uncertain Mixed skin: 13.3 -CADM1 BL2, IGSF4, IGSF4A, Necl-2, NECL2, RA175, ST17, SYNCAM, SYNCAM1, TSLC1 ENSG00000182985 Cell adhesion molecule 1 11 115169218-115504957 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037266 Supported Supported Cell Junctions Mixed parathyroid gland: 119.5 -ZNF320 DKFZp686G16228, ZFPL ENSG00000182986 Zinc finger protein 320 19 52863790-52897693 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043696 Uncertain Approved Nucleoli
Cytosol Mixed parathyroid gland: 25.1 -C12orf60 MGC47869 ENSG00000182993 Chromosome 12 open reading frame 60 12 14803572-14906586 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043911 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 testis: 23.8 adrenal gland: 6.0 -PYCR1 P5C ENSG00000183010 Pyrroline-5-carboxylate reductase 1 17 81932384-81942412 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047660 Approved Mixed salivary gland: 52.6 -NAA38 LSMD1, MGC14151, PFAAP2 ENSG00000183011 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 17 7856685-7885238 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059189 Supported Nucleus Expressed in all testis: 78.6 -SPNS2 ENSG00000183018 Spinster homolog 2 (Drosophila) 17 4498838-4539035 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA068717 Uncertain Tissue enhanced 0 esophagus: 46.5 kidney: 29.9 -MCEMP1 C19orf59, MGC132456 ENSG00000183019 Mast cell-expressed membrane protein 1 19 7676628-7679826 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014731 Supported Group enriched 9 appendix: 28.5;bone marrow: 43.9;lung: 110.4 smooth muscle: 6.9 -AP2A2 ADTAB, CLAPA2, DKFZP564D1864, HIP9, HYPJ, KIAA0899 ENSG00000183020 Adaptor-related protein complex 2, alpha 2 subunit 11 924894-1012245 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017514, HPA043040 Supported Validated Nucleoplasm
Vesicles Mixed spleen: 16.6 -SLC8A1 NCX1 ENSG00000183023 Solute carrier family 8 (sodium/calcium exchanger), member 1 2 40097270-40611053 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022694, HPA070007 Uncertain Supported Nucleoplasm
Plasma membrane Tissue enhanced 0 heart muscle: 79.5 seminal vesicle: 38.2 -OR1G1 OR17-209, OR1G2 ENSG00000183024 Olfactory receptor, family 1, subfamily G, member 1 17 3126584-3127581 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.2 -SLC25A21 ODC, ODC1 ENSG00000183032 Solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 14 36677921-37172866 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000662 Uncertain Mixed testis: 7.6 -OTOP2 ENSG00000183034 Otopetrin 2 17 74924275-74933912 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA024524, HPA053090 Uncertain Tissue enhanced 0 colon: 20.3;rectum: 11.6 testis: 3.9 -CYLC1 ENSG00000183035 Cylicin, basic protein of sperm head cytoskeleton 1 X 83861126-83886699 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA070355 Supported Tissue enriched 428 testis: 42.7 adipose tissue: 0.0 -PCP4 PEP-19 ENSG00000183036 Purkinje cell protein 4 21 39867317-39929397 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005792 Supported Supported Approved Nucleus
Nucleoli
Cytosol Tissue enhanced 0 prostate: 412.7;seminal vesicle: 1194.8 epididymis: 295.1 -ABAT GABAT ENSG00000183044 4-aminobutyrate aminotransferase 16 8674565-8784575 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041528, HPA041690 Supported Supported Mitochondria Tissue enhanced 0 cerebral cortex: 165.0;kidney: 134.3;liver: 175.2 thyroid gland: 47.2 -SLC25A10 DIC ENSG00000183048 Solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 17 81712236-81721016 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023048 Supported Supported Nucleoplasm
Mitochondria Mixed kidney: 35.3 -CAMK1D CKLiK ENSG00000183049 Calcium/calmodulin-dependent protein kinase ID 10 12349482-12835545 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007266 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 cerebral cortex: 52.2 skin: 22.0 -RGPD6 RGP6 ENSG00000183054 RANBP2-like and GRIP domain containing 6 2 110513812-110577185 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045704, HPA049497, HPA051675, HPA067564 Uncertain Uncertain Nuclear membrane
Vesicles Expressed in all testis: 82.8 -LYSMD4 FLJ33008 ENSG00000183060 LysM, putative peptidoglycan-binding, domain containing 4 15 99715697-99733561 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029152, HPA059824 Approved Approved Actin filaments
Cytosol Mixed skin: 18.4 -WBP2NL FLJ26145, MGC26816, PAWP ENSG00000183066 WBP2 N-terminal like 22 41998725-42058456 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA048557 Supported Tissue enriched 8 testis: 11.6 epididymis: 1.5 -IGSF5 JAM4 ENSG00000183067 Immunoglobulin superfamily, member 5 21 39745407-39802096 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057282 Uncertain Mixed placenta: 3.7 -NKX2-5 CSX, CSX1, NKX2.5, NKX2E, NKX4-1 ENSG00000183072 NK2 homeobox 5 5 173232109-173235357 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065034 Approved Nucleoplasm
Cytosol Group enriched 130 heart muscle: 33.8;spleen: 14.8 breast: 0.1 -AFMID DKFZp686F03259, KF ENSG00000183077 Arylformamidase 17 78187317-78207701 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023861, HPA026536 Uncertain Approved Mitochondria Expressed in all kidney: 87.0 -GAS6 AXLLG, AXSF, DKFZp666G247, FLJ34709 ENSG00000183087 Growth arrest-specific 6 13 113820549-113864067 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008275, HPA056080 Approved Approved Microtubule organizing center
Cytosol Expressed in all fallopian tube: 192.6 -FREM3 ENSG00000183090 FRAS1 related extracellular matrix 3 4 143577302-143700675 Predicted secreted proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA041641 Uncertain Tissue enhanced 0 cerebral cortex: 1.6 lung: 0.6 -NEB NEB177D, NEM2 ENSG00000183091 Nebulin 2 151485336-151734487 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016601 Supported Tissue enriched 110 skeletal muscle: 3274.3 prostate: 29.6 -BEGAIN KIAA1446 ENSG00000183092 Brain-enriched guanylate kinase-associated 14 100537149-100587413 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002899 Uncertain Uncertain Nucleus
Golgi apparatus
Cytosol Tissue enhanced 0 cerebral cortex: 21.4 adrenal gland: 5.1 -GPC6 ENSG00000183098 Glypican 6 13 93226842-94407401 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017671 Approved Approved Golgi apparatus
Vesicles Mixed gallbladder: 27.4 -ARHGEF37 FLJ41603 ENSG00000183111 Rho guanine nucleotide exchange factor (GEF) 37 5 149551947-149634968 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043885, HPA053487 Uncertain Approved Cytosol Expressed in all parathyroid gland: 67.1 -FAM43B FLJ44952 ENSG00000183114 Family with sequence similarity 43, member B 1 20552439-20555010 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA050813 Approved Approved Cytosol Tissue enhanced 0 adrenal gland: 10.4 epididymis: 3.4 -CSMD1 KIAA1890, PPP1R24 ENSG00000183117 CUB and Sushi multiple domains 1 8 2935353-4994972 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA074707 Approved Vesicles Tissue enhanced 0 cerebral cortex: 6.2;testis: 4.7 fallopian tube: 1.1 -CALHM3 bA225H22.7, FAM26A ENSG00000183128 Calcium homeostasis modulator 3 10 103472804-103479240 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018205 Uncertain Approved Nucleoplasm Not detected testis: 0.4 -OR2T11 OR2T11Q ENSG00000183130 Olfactory receptor, family 2, subfamily T, member 11 (gene/pseudogene) 1 248626178-248627128 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA047416 Uncertain Not detected epididymis: 0.0 -PTGDR2 CD294, CRTH2, DP2, GPR44 ENSG00000183134 Prostaglandin D2 receptor 2 11 60850940-60855971 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014259 Uncertain Tissue enhanced 0 small intestine: 7.3;stomach: 7.5 parathyroid gland: 5.3 -CEP57L1 bA487F23.2, C6orf182, MGC21731 ENSG00000183137 Centrosomal protein 57kDa-like 1 6 109095110-109163932 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040378 Approved Approved Plasma membrane
Cytosol Expressed in all testis: 47.4 -RIPPLY3 DSCR6 ENSG00000183145 Ripply transcriptional repressor 3 21 37006150-37019659 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055541 Uncertain Not detected prostate: 0.2 -PRORY CYorf17 ENSG00000183146 Proline rich, Y-linked Y 21382954-21386360 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 small intestine: 1.9 rectum: 0.7 -ANKRD20A2 ENSG00000183148 Ankyrin repeat domain 20 family, member A2 9 40223285-40266392 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA043239, HPA047112, HPA047167, HPA047766, HPA051753 Uncertain Tissue enriched 7 testis: 4.7 spleen: 0.7 -GPR19 ENSG00000183150 G protein-coupled receptor 19 12 12660891-12696207 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA013955 Uncertain Tissue enhanced 0 cerebral cortex: 8.5;testis: 7.7 appendix: 2.8 -GJD3 Cx30.2, CX31.9, GJA11, GJC1 ENSG00000183153 Gap junction protein, delta 3, 31.9kDa 17 40362931-40363815 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 spleen: 7.3 seminal vesicle: 3.4 -RABIF mss4, RASGRF3 ENSG00000183155 RAB interacting factor 1 202878957-202889135 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027715 Approved Mixed testis: 26.1 -TMEM119 ENSG00000183160 Transmembrane protein 119 12 108589846-108598320 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051870, HPA052650 Supported Mixed cervix: 92.4 -FANCF FAF ENSG00000183161 Fanconi anemia, complementation group F 11 22622519-22626787 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed fallopian tube: 10.9 -CALN1 ENSG00000183166 Calneuron 1 7 71779491-72447151 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036278, HPA036708 Approved Uncertain Vesicles
Plasma membrane Group enriched 5 adrenal gland: 14.8;cerebral cortex: 46.5 testis: 6.0 -SMDT1 C22orf32, DDDD, dJ186O1.1, EMRE ENSG00000183172 Single-pass membrane protein with aspartate-rich tail 1 22 42079691-42084284 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032117, HPA060340 Uncertain Supported Nucleus
Mitochondria Expressed in all thyroid gland: 7.8 -GABRR3 ENSG00000183185 Gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 3 97986673-98035304 FDA approved drug targets, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.2 -C2CD4C FAM148C, KIAA1957, NLF3 ENSG00000183186 C2 calcium-dependent domain containing 4C 19 405438-409170 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055915 Uncertain Approved Vesicles Group enriched 6 adipose tissue: 2.5;cerebral cortex: 10.7;gallbladder: 4.4 endometrium: 0.9 -CHST6 MCDC1 ENSG00000183196 Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 16 75472052-75495384 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cervix, uterine: 16.4;duodenum: 10.9;small intestine: 11.2 cerebral cortex: 7.9 -POTEC A26B2, CT104.6, DKFZp686J0529, POTE-18, POTE18 ENSG00000183206 POTE ankyrin domain family, member C 18 14507339-14543585 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042822 Uncertain Tissue enriched 7 testis: 1.4 prostate: 0.2 -RUVBL2 ECP51, INO80J, Reptin52, RVB2, TIH2, TIP48, TIP49b ENSG00000183207 RuvB-like AAA ATPase 2 19 48993448-49015995 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012432, HPA042880, HPA067966 Supported Supported Nucleoplasm
Centrosome
Cytosol Expressed in all testis: 71.6 -GDPGP1 C15orf58 ENSG00000183208 GDP-D-glucose phosphorylase 1 15 90233808-90245811 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048189, HPA059841 Approved Approved Cytosol Mixed parathyroid gland: 9.3 -CTNNA3 MGC26194, VR22 ENSG00000183230 Catenin (cadherin-associated protein), alpha 3 10 65912518-67696169 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017977, HPA061818 Supported Tissue enhanced 0 cerebral cortex: 8.5;heart muscle: 11.2 liver: 4.3 -RIMBP3C ENSG00000183246 RIMS binding protein 3C 22 21545357-21551461 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA001183 Supported Uncertain Vesicles
Plasma membrane Tissue enriched 32 testis: 15.7 spleen: 0.4 -PRR36 ENSG00000183248 Proline rich 36 19 7868719-7874379 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062741 Uncertain Approved Nucleus
Golgi apparatus Tissue enriched 10 cerebral cortex: 18.0 prostate: 1.7 -OR51B4 ENSG00000183251 Olfactory receptor, family 51, subfamily B, member 4 11 5301014-5301996 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected testis: 0.2 -PTTG1IP C21orf1, C21orf3, PBF ENSG00000183255 Pituitary tumor-transforming 1 interacting protein 21 44849585-44873903 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034146, HPA061827 Uncertain Supported Nucleoplasm Expressed in all placenta: 241.9 -DDX41 ABS, MGC8828 ENSG00000183258 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 5 177511577-177517469 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017911, HPA048803 Supported Supported Nucleus Expressed in all cerebral cortex: 52.7 -ABHD16B C20orf135, dJ591C20.1 ENSG00000183260 Abhydrolase domain containing 16B 20 63861498-63862988 Plasma proteins, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA059272 Uncertain Approved Nucleoplasm Mixed testis: 5.8 -OR52E8 ENSG00000183269 Olfactory receptor, family 52, subfamily E, member 8 11 5856674-5857734 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -CCDC60 MGC39827 ENSG00000183273 Coiled-coil domain containing 60 12 119334712-119541047 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 fallopian tube: 27.7;testis: 19.6 cervix: 8.1 -PLGLB1 PLGL, PRP-B ENSG00000183281 Plasminogen-like B1 2 87002559-87021852 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA053770 Approved Vesicles Tissue enriched 6 liver: 120.4 epididymis: 19.1 -DAZAP2 KIAA0058 ENSG00000183283 DAZ associated protein 2 12 51238292-51271362 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045940 Supported Nuclear speckles Expressed in all bone marrow: 337.2 -CCBE1 FLJ30681, KIAA1983 ENSG00000183287 Collagen and calcium binding EGF domains 1 18 59430940-59697380 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041361, HPA041374 Uncertain Validated Plasma membrane
Cytosol Tissue enhanced 0 ovary: 40.6 cervix: 15.9 -SEP15 ENSG00000183291 15 kDa selenoprotein 1 86862445-86914424 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054937 Approved Nucleoli
Cytosol Expressed in all thyroid gland: 360.2 -TISP43 ENSG00000183292 Uncharacterized LOC150527 2 130570829-130584161 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA044732 Uncertain Tissue enriched 11 testis: 11.6 skin: 1.0 -OR5P2 JCG3 ENSG00000183303 Olfactory receptor, family 5, subfamily P, member 2 11 7795905-7796973 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected skin: 0.1 -FAM9A TEX39A ENSG00000183304 Family with sequence similarity 9, member A X 8790795-8801383 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056076 Uncertain Tissue enriched 18 testis: 7.2 stomach: 0.4 -MAGEA2B MAGE2, MAGEA2, MAGEA2b, MGC16973 ENSG00000183305 Melanoma antigen family A2B X 152714586-152718607 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 9 testis: 1.9 placenta: 0.2 -CECR6 ENSG00000183307 Cat eye syndrome chromosome region, candidate 6 22 17116299-17121367 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA068790 Approved Nucleoplasm
Vesicles
Plasma membrane Group enriched 7 cerebral cortex: 15.0;prostate: 10.9 testis: 1.9 -ZNF623 KIAA0628 ENSG00000183309 Zinc finger protein 623 8 143636013-143656418 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044372 Uncertain Approved Nucleus Mixed endometrium: 6.1 -OR2T34 ENSG00000183310 Olfactory receptor, family 2, subfamily T, member 34 1 248573801-248574757 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -OR52L1 ENSG00000183313 Olfactory receptor, family 52, subfamily L, member 1 11 5985892-5986985 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.1 -EPHA10 FLJ16103, FLJ33655 ENSG00000183317 EPH receptor A10 1 37713880-37765133 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027497 Uncertain Tissue enhanced 0 testis: 20.4 colon: 8.1 -SPDYE4 ENSG00000183318 Speedy/RINGO cell cycle regulator family member E4 17 8753106-8758559 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA025704, HPA051750 Uncertain Tissue enriched 21 testis: 10.9 bone marrow: 0.5 -CCDC125 KENAE ENSG00000183323 Coiled-coil domain containing 125 5 69280175-69332809 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041878 Approved Uncertain Nucleoplasm
Nuclear membrane
Intermediate filaments Mixed prostate: 11.7 -REC114 C15orf60, CT147, FLJ27520, FLJ36860, FLJ44083, LOC283677 ENSG00000183324 REC114 meiotic recombination protein 15 73443158-73560014 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 64 testis: 63.4 heart muscle: 0.9 -BOLA2 BOLA2A, My016 ENSG00000183336 BolA family member 2 16 29443056-29454964 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045380, HPA046696 Supported Uncertain Nucleus Mixed duodenum: 12.3 -BCOR FLJ20285, KIAA1575 ENSG00000183337 BCL6 corepressor X 40049815-40177329 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056308, HPA066234 Validated Nucleus Expressed in all parathyroid gland: 33.3 -JRKL HHMJG ENSG00000183340 JRK-like 11 96389989-96507574 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046184 Uncertain Approved Vesicles Expressed in all parathyroid gland: 19.1 -C10orf107 bA63A2.1, Em:AC022398.2, MGC44593 ENSG00000183346 Chromosome 10 open reading frame 107 10 61662961-61766766 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA041398 Supported Uncertain Nucleoplasm
Centrosome
Cytosol Tissue enhanced 0 fallopian tube: 43.7;testis: 30.2 parathyroid gland: 12.4 -GBP6 DKFZp686G0786 ENSG00000183347 Guanylate binding protein family, member 6 1 89364058-89386461 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA027744 Supported Tissue enriched 7 esophagus: 450.3 tonsil: 68.6 -KIAA2026 FLJ20375 ENSG00000183354 KIAA2026 9 5881596-6007901 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA002109 Uncertain Approved Nucleus
Vesicles
Cytosol Expressed in all testis: 22.9 -OVCH2 OVTN ENSG00000183378 Ovochymase 2 (gene/pseudogene) 11 7689438-7706421 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 21 epididymis: 202.2 skin: 9.5 -SYNDIG1L capucin, IFITMD4, TMEM90A ENSG00000183379 Synapse differentiation inducing 1-like 14 74405893-74426102 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA042594, HPA048487 Uncertain Tissue enriched 10 epididymis: 13.2 lung: 1.3 -FHL3 SLIM2 ENSG00000183386 Four and a half LIM domains 3 1 37996770-38005606 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045723 Approved Nucleus Tissue enriched 13 skeletal muscle: 569.2 smooth muscle: 42.9 -OR56A4 ENSG00000183389 Olfactory receptor, family 56, subfamily A, member 4 11 6001986-6003194 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -PMCH MCH ENSG00000183395 Pro-melanin-concentrating hormone 12 102196459-102197845 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046055, HPA061884 Supported Tissue enhanced 0 lymph node: 1.1 appendix: 0.8 -TMEM89 ENSG00000183396 Transmembrane protein 89 3 48620759-48621855 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA053577 Uncertain Tissue enriched 10 testis: 9.4 bone marrow: 0.9 -C19orf71 LOC100128569 ENSG00000183397 Chromosome 19 open reading frame 71 19 3539154-3544030 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA048654 Uncertain Approved Endoplasmic reticulum
Plasma membrane
Cytosol Mixed testis: 29.7 -CCDC159 ENSG00000183401 Coiled-coil domain containing 159 19 11344684-11354944 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047126, HPA054655 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all parathyroid gland: 64.3 -RIPK4 ANKK2, ANKRD3, DIK, PKK, RIP4 ENSG00000183421 Receptor-interacting serine-threonine kinase 4 21 41739369-41767106 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 esophagus: 31.6 small intestine: 15.3 -LRIT3 CSNB1F, FIGLER4, FLJ44691 ENSG00000183423 Leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 4 109848202-109872315 Disease related genes, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level HPA013454 Uncertain Approved Nucleoplasm
Mitochondria
Cytosol Not detected kidney: 0.9 -NPIPA1 morpheus, NPIP ENSG00000183426 Nuclear pore complex interacting protein family, member A1 16 14750813-14952060 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA053611 Supported Approved Nucleoplasm Mixed ovary: 68.2 -SF3A3 PRP9, PRPF9, SAP61, SF3a60 ENSG00000183431 Splicing factor 3a, subunit 3, 60kDa 1 37956975-37990921 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032054, HPA032055 Supported Validated Nucleoplasm Expressed in all endometrium: 35.1 -TFDP3 CT30, E2F-like, HCA661 ENSG00000183434 Transcription factor Dp family, member 3 X 133216669-133218348 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 12 testis: 8.0 breast: 0.6 -TRIM61 RNF35 ENSG00000183439 Tripartite motif containing 61 4 164954446-164977668 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049109 Uncertain Approved Nucleoli fibrillar center
Endoplasmic reticulum Tissue enhanced 0 testis: 10.5 thyroid gland: 4.3 -GRIN2A GluN2A, NMDAR2A ENSG00000183454 Glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16 9753404-10182754 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022725 Supported Tissue enriched 5 cerebral cortex: 25.0 testis: 4.7 -URAD PRHOXNB ENSG00000183463 Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase 13 27977714-27988654 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA038972 Uncertain Group enriched 5 colon: 13.0;duodenum: 8.5;small intestine: 18.3 appendix: 2.4 -GTF2H2C ENSG00000183474 GTF2H2 family member C 5 69560208-69594723 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047001 Approved Nuclear speckles Mixed thyroid gland: 8.2 -ASB7 ENSG00000183475 Ankyrin repeat and SOCS box containing 7 15 100602534-100651705 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003300 Approved Approved Nucleus
Golgi apparatus
Vesicles Mixed testis: 12.5 -SH2D7 LOC646892 ENSG00000183476 SH2 domain containing 7 15 78077808-78104909 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA051320 Approved Group enriched 7 colon: 1.7;duodenum: 2.2;small intestine: 1.9;testis: 5.7 cerebral cortex: 0.4 -TREX2 ENSG00000183479 Three prime repair exonuclease 2 X 153444720-153470587 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054060 Uncertain Tissue enriched 8 skin: 28.8 seminal vesicle: 3.4 -GPR132 G2A ENSG00000183484 G protein-coupled receptor 132 14 105049389-105065445 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA029694, HPA029695 Supported Mixed appendix: 9.7 -MX2 MXB ENSG00000183486 MX dynamin-like GTPase 2 21 41361943-41409390 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030235 Uncertain Mixed spleen: 46.7 -EP400 CAGH32, DKFZP434I225, KIAA1498, KIAA1818, P400, TNRC12 ENSG00000183495 E1A binding protein p400 12 131949920-132081102 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016704, HPA049013 Supported Supported Nucleus Expressed in all testis: 20.8 -MEX3B DKFZp434J0617, RKHD3, RNF195 ENSG00000183496 Mex-3 RNA binding family member B 15 82041778-82046141 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041093 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 41.7 endometrium: 10.1 -FAM46C FLJ20202 ENSG00000183508 Family with sequence similarity 46, member C 1 117605934-117628372 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054049 Uncertain Approved Nucleoplasm Mixed testis: 58.4 -COA5 C2orf64, FLJ27524, MGC52110, Pet191 ENSG00000183513 Cytochrome c oxidase assembly factor 5 2 98599310-98608515 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057768 Uncertain Supported Mitochondria Expressed in all cerebral cortex: 42.5 -UTP11L CGI-94 ENSG00000183520 UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) 1 38009258-38024824 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045830 Approved Approved Nucleus Expressed in all skeletal muscle: 37.3 -PSMG1 c21-LRP, DSCR2, LRPC21, PAC1 ENSG00000183527 Proteasome (prosome, macropain) assembly chaperone 1 21 39174769-39183851 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057193, HPA070225 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all testis: 68.5 -PRR14L C22orf30, MGC50372 ENSG00000183530 Proline rich 14-like 22 31676256-31750140 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062645 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 14.9 -KLRC4 NKG2-F ENSG00000183542 Killer cell lectin-like receptor subfamily C, member 4 12 10407382-10409757 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 spleen: 13.3 lymph node: 5.6 -ACSM5 FLJ20581 ENSG00000183549 Acyl-CoA synthetase medium-chain family member 5 16 20409534-20441336 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041435 Uncertain Tissue enhanced 0 liver: 142.5 kidney: 29.2 -C10orf120 bA318C4.1 ENSG00000183559 Chromosome 10 open reading frame 120 10 122697709-122699822 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 379 testis: 49.1 epididymis: 0.1 -IZUMO1R Folbp3, FOLR4, JUNO ENSG00000183560 IZUMO1 receptor, JUNO 11 94305593-94307721 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adrenal gland: 1.0 lymph node: 0.7 -SERHL2 ENSG00000183569 Serine hydrolase-like 2 22 42553617-42574382 Plasma proteins, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12 breast: 546.8 epididymis: 46.2 -PCBP3 ENSG00000183570 Poly(rC) binding protein 3 21 45643694-45942454 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030247 Approved Tissue enhanced 0 testis: 21.6 cerebral cortex: 12.8 -PGPEP1L ENSG00000183571 Pyroglutamyl-peptidase I-like 15 98968230-99007795 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041781 Uncertain Group enriched 6 heart muscle: 2.2;skeletal muscle: 9.6;testis: 3.3 breast: 0.8 -SETD3 C14orf154, FLJ23027 ENSG00000183576 SET domain containing 3 14 99397746-99480889 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003591, HPA003639 Approved Approved Mitochondria Expressed in all testis: 153.6 -TNFAIP8L3 FLJ41287 ENSG00000183578 Tumor necrosis factor, alpha-induced protein 8-like 3 15 51056598-51105276 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048372 Uncertain Tissue enhanced 0 endometrium: 118.6;smooth muscle: 105.4 fallopian tube: 33.7 -ZNRF3 BK747E2.3, FLJ22057, KIAA1133, RNF203 ENSG00000183579 Zinc and ring finger 3 22 28883592-29057487 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036702, HPA036703 Uncertain Uncertain Golgi apparatus Mixed epididymis: 16.2 -FBXL7 FBL6, FBL7, KIAA0840 ENSG00000183580 F-box and leucine-rich repeat protein 7 5 15500196-15939795 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055464 Uncertain Mixed endometrium: 36.3 -TANGO2 C22orf25, DKFZp761P1121 ENSG00000183597 Transport and golgi organization 2 homolog 22 20017014-20065926 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA003080 Approved Approved Expressed in all heart muscle: 46.6 -HIST2H3D ENSG00000183598 Histone cluster 2, H3d 1 149813271-149813681 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Mixed bone marrow: 2.5 -SFXN4 ENSG00000183605 Sideroflexin 4 10 119140767-119165667 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018028, HPA020872 Approved Supported Vesicles Expressed in all thyroid gland: 47.1 -GKN2 blottin, BRICD1B, GDDR, PRO813, TFIZ1, VLTI465 ENSG00000183607 Gastrokine 2 2 68945232-68952970 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057765 Supported Tissue enriched 37 stomach: 3848.0 lung: 103.9 -FAM167B C1orf90, MGC10820 ENSG00000183615 Family with sequence similarity 167, member B 1 32247233-32248856 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029398, HPA062074 Approved Approved Actin filaments Mixed thyroid gland: 9.4 -MRPL54 ENSG00000183617 Mitochondrial ribosomal protein L54 19 3762664-3768575 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042117, HPA046767 Uncertain Approved Mitochondria Expressed in all thyroid gland: 89.8 -ZNF438 bA330O11.1 ENSG00000183621 Zinc finger protein 438 10 30820207-31031937 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039843 Uncertain Supported Nucleoplasm
Cytosol Mixed thyroid gland: 16.2 -HMCES C3orf37, DC12, SRAPD1 ENSG00000183624 5-hydroxymethylcytosine (hmC) binding, ES cell-specific 3 129278828-129306186 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044968 Approved Approved Nucleus Expressed in all parathyroid gland: 201.5 -CCR3 CC-CKR-3, CD193, CKR3, CMKBR3 ENSG00000183625 Chemokine (C-C motif) receptor 3 3 46163604-46266706 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB003795 Uncertain Mixed small intestine: 3.0 -DGCR6 ENSG00000183628 DiGeorge syndrome critical region gene 6 22 18906028-18914238 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed cerebral cortex: 12.0 -GOLGA8G DKFZp434K052 ENSG00000183629 Golgin A8 family, member G 15 28519611-28533014 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 35 testis: 3.5 adipose tissue: 0.0 -PRR32 CXorf64 ENSG00000183631 Proline rich 32 X 126819764-126821786 Predicted intracellular proteins No evidence No evidence No evidence HPA048386 Uncertain Not detected fallopian tube: 0.9 -TP53TG3 P53TG3, TP53TG3A ENSG00000183632 TP53 target 3 16 32673528-32676732 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected placenta: 0.4 -RP1L1 DCDC4B ENSG00000183638 Retinitis pigmentosa 1-like 1 8 10606349-10712187 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA024686, HPA024744 Supported Not detected skin: 0.2 -KRTAP8-1 KAP8.1 ENSG00000183640 Keratin associated protein 8-1 21 30812697-30813252 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.3 -C11orf88 FLJ46266 ENSG00000183644 Chromosome 11 open reading frame 88 11 111514785-111537031 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 140.3;testis: 39.5 lung: 18.0 -ZNF530 KIAA1508 ENSG00000183647 Zinc finger protein 530 19 57599885-57612722 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045868 Uncertain Approved Vesicles Mixed spleen: 3.2 -NDUFB1 CI-MNLL, MNLL ENSG00000183648 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 14 92116122-92121917 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063737 Supported Nuclear speckles
Mitochondria Expressed in all skeletal muscle: 278.9 -MARCH11 MARCH-XI ENSG00000183654 Membrane-associated ring finger (C3HC4) 11 5 16067139-16180762 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA077262 Uncertain Vesicles Tissue enriched 20 testis: 89.9 cerebral cortex: 4.5 -KLHL25 ENC-2, ENC2, FLJ12587 ENSG00000183655 Kelch-like family member 25 15 85759323-85795030 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023450 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 15.8 testis: 9.9 -FAM19A1 TAFA-1 ENSG00000183662 Family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 3 68004216-68545625 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA013407 Approved Tissue enriched 6 cerebral cortex: 30.9 seminal vesicle: 5.5 -TRMT12 FLJ20772, Trm12, TYW2 ENSG00000183665 TRNA methyltransferase 12 homolog (S. cerevisiae) 8 124450820-124462150 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023939 Approved Approved Nucleoplasm
Mitochondria Mixed thyroid gland: 14.7 -PSG9 PSG11, PSGII ENSG00000183668 Pregnancy specific beta-1-glycoprotein 9 19 43211791-43269530 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046327 Approved Tissue enriched 120 placenta: 146.9 smooth muscle: 1.2 -GPR1 ENSG00000183671 G protein-coupled receptor 1 2 206175316-206218047 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA010525 Uncertain Supported Vesicles
Plasma membrane Tissue enhanced 0 placenta: 11.2 esophagus: 5.5 -BMP8A ENSG00000183682 Bone morphogenetic protein 8a 1 39491646-39525935 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 19 thyroid gland: 80.6 testis: 4.2 -ALYREF ALY, ALY/REF, BEF, REF, THOC4 ENSG00000183684 Aly/REF export factor 17 81887844-81891586 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB016281, HPA019799, HPA061282 Supported Validated Nuclear speckles Expressed in all testis: 88.5 -FAM101B MGC45871 ENSG00000183688 Family with sequence similarity 101, member B 17 439978-445939 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030879 Uncertain Approved Plasma membrane
Actin filaments
Cytosol Tissue enhanced 0 bone marrow: 98.8 placenta: 30.3 -EFHC2 FLJ22843, MRX74 ENSG00000183690 EF-hand domain (C-terminal) containing 2 X 44147882-44343672 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA034492 Uncertain Tissue enhanced 0 fallopian tube: 25.5;testis: 15.3 endometrium: 6.7 -NOG SYM1, SYNS1 ENSG00000183691 Noggin 17 56593699-56595590 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061318 Approved Group enriched 5 cerebral cortex: 7.3;placenta: 15.8 lymph node: 2.2 -MRGPRX2 MRGX2 ENSG00000183695 MAS-related GPR, member X2 11 19054455-19060681 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055220 Approved Tissue enhanced 0 breast: 1.2;skin: 1.2 cervix: 0.6 -UPP1 UDRPASE, UP, UPASE, UPP ENSG00000183696 Uridine phosphorylase 1 7 48088628-48108733 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054040, HPA055394 Uncertain Validated Nucleoplasm Tissue enhanced 0 esophagus: 35.2 appendix: 18.3 -OR4N4 ENSG00000183706 Olfactory receptor, family 4, subfamily N, member 4 15 22094431-22095556 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057442 Uncertain Uncertain Centrosome Tissue enriched 103 testis: 10.3 cervix: 0.1 -IFNL2 IL-28A, IL28A ENSG00000183709 Interferon, lambda 2 19 39268514-39270092 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB025489 Uncertain Not detected testis: 0.1 -OPCML IGLON1, OBCAM, OPCM ENSG00000183715 Opioid binding protein/cell adhesion molecule-like 11 132414977-133532519 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 9 cerebral cortex: 63.2 parathyroid gland: 7.4 -TRIM52 RNF102 ENSG00000183718 Tripartite motif containing 52 5 181254417-181261139 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA054565, HPA056819 Uncertain Supported Nucleoli
Intermediate filaments Expressed in all parathyroid gland: 17.9 -LHFP MGC22429 ENSG00000183722 Lipoma HMGIC fusion partner 13 39342892-39603528 Cancer-related genes, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058975 Approved Approved Nucleoli Mixed placenta: 195.0 -CMTM4 CKLFSF4 ENSG00000183723 CKLF-like MARVEL transmembrane domain containing 4 16 66614750-66696707 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014704, HPA023890 Supported Approved Golgi apparatus
Vesicles
Plasma membrane Tissue enhanced 0 thyroid gland: 63.9 parathyroid gland: 47.2 -TMEM50A SMP1 ENSG00000183726 Transmembrane protein 50A 1 25337917-25362361 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065192 Approved Plasma membrane
Actin filaments
Cytosol Expressed in all prostate: 71.1 -NPBWR1 GPR7 ENSG00000183729 Neuropeptides B/W receptor 1 8 52938431-52941117 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Not detected cerebral cortex: 0.7 -FIGLA bHLHc8 ENSG00000183733 Folliculogenesis specific bHLH transcription factor 2 70777310-70790643 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 6 testis: 1.2 cervix: 0.2 -ASCL2 ASH2, bHLHa45, HASH2 ENSG00000183734 Achaete-scute family bHLH transcription factor 2 11 2268495-2270952 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed placenta: 6.4 -TBK1 NAK ENSG00000183735 TANK-binding kinase 1 12 64451880-64502108 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045797, HPA060211 Uncertain Supported Nucleoplasm Expressed in all testis: 49.2 -CBX6 ENSG00000183741 Chromobox homolog 6 22 38861450-38872314 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048653 Uncertain Approved Nucleus
Mitochondria Expressed in all parathyroid gland: 103.9 -MACC1 7A5, SH3BP4L ENSG00000183742 Metastasis associated in colon cancer 1 7 20134655-20217404 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020081, HPA020103, HPA029476, CAB068194 Supported Approved Mitochondria Mixed small intestine: 13.2 -ACSM2A A-923A4.1, ACSM2, MGC150530 ENSG00000183747 Acyl-CoA synthetase medium-chain family member 2A 16 20451461-20487667 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA057699 Supported Group enriched 578 kidney: 284.3;liver: 185.7 cerebral cortex: 0.4 -TBL3 SAZD, UTP13 ENSG00000183751 Transducin (beta)-like 3 16 1972037-1982933 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042562, HPA055695 Supported Validated Nucleoli Mixed testis: 5.7 -BPY2 BPY2A, VCY2, VCY2A ENSG00000183753 Basic charge, Y-linked, 2 Y 22973819-23005465 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 testis: 2.1 kidney: 0.1 -PAPL ENSG00000183760 Iron/zinc purple acid phosphatase-like protein 19 39083913-39111493 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042005, HPA042613 Uncertain Group enriched 6 cerebral cortex: 1.8;skin: 6.9;tonsil: 2.5 epididymis: 0.6 -KREMEN1 KREMEN, KRM1 ENSG00000183762 Kringle containing transmembrane protein 1 22 29073078-29168333 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA058513 Approved Nucleoplasm
Nuclear bodies
Cytosol Mixed skin: 43.5 -TRAIP RNF206, TRIP ENSG00000183763 TRAF interacting protein 3 49828599-49856574 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036261, HPA036262 Approved Supported Plasma membrane
Cytosol Mixed testis: 11.3 -CHEK2 bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53 ENSG00000183765 Checkpoint kinase 2 22 28687743-28742422 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001878, CAB002030 Approved Supported Nucleoplasm
Golgi apparatus Mixed testis: 13.2 -FOXL2 BPES, BPES1 ENSG00000183770 Forkhead box L2 3 138944224-138947140 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069613 Supported Supported Nucleus
Cytokinetic bridge Tissue enhanced 0 endometrium: 12.1;ovary: 29.6;parathyroid gland: 24.2 fallopian tube: 7.6 -AIFM3 AIFL, FLJ30473 ENSG00000183773 Apoptosis-inducing factor, mitochondrion-associated, 3 22 20965108-20981360 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001271 Validated Mitochondria Tissue enhanced 0 cerebral cortex: 18.6;colon: 19.1 rectum: 9.1 -KCTD16 KIAA1317 ENSG00000183775 Potassium channel tetramerization domain containing 16 5 144170832-144485686 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044590, HPA050154 Approved Approved Nuclear speckles Group enriched 7 cerebral cortex: 12.3;testis: 3.0 lung: 1.1 -B3GALT5 B3GalT-V, B3T5, beta3Gal-T5, GLCT5 ENSG00000183778 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 21 39556442-39673137 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054092, HPA054684 Approved Group enriched 5 colon: 23.1;duodenum: 28.2;gallbladder: 8.6;rectum: 41.3;small intestine: 37.9 stomach: 5.1 -ZNF703 FLJ14299, NLZ1, ZEPPO1, ZNF503L, Zpo1 ENSG00000183779 Zinc finger protein 703 8 37695751-37700021 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023930, CAB068249 Supported Mixed fallopian tube: 30.4 -SLC35F3 FLJ37712 ENSG00000183780 Solute carrier family 35, member F3 1 233904933-234324516 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051327, HPA061582 Uncertain Approved Nucleoli
Golgi apparatus Tissue enhanced 0 cerebral cortex: 10.2 breast: 3.0 -KCTD8 ENSG00000183783 Potassium channel tetramerization domain containing 8 4 44173909-44448807 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031562 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 11.5;thyroid gland: 5.1 testis: 2.4 -C9orf66 FLJ31158 ENSG00000183784 Chromosome 9 open reading frame 66 9 212824-215741 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035652 Uncertain Tissue enhanced 0 kidney: 17.7 adrenal gland: 4.1 -TUBA8 TUBAL2 ENSG00000183785 Tubulin, alpha 8 22 18110331-18146554 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043684, CAB046031, HPA063394 Approved Supported Microtubules Group enriched 6 cerebral cortex: 28.7;heart muscle: 85.0;skeletal muscle: 121.8;testis: 47.4 thyroid gland: 11.2 -TCEB3C HsT829, TCEB3L2 ENSG00000183791 Transcription elongation factor B polypeptide 3C (elongin A3) 18 47028202-47030078 Plasma proteins, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA048971, HPA049178, HPA050086 Uncertain Not detected adipose tissue: 0.0 -NPIPA5 ENSG00000183793 Nuclear pore complex interacting protein family, member A5 16 15363624-15381047 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA053611 Approved Approved Nucleoplasm Mixed testis: 17.2 -BPY2B VCY2B ENSG00000183795 Basic charge, Y-linked, 2B Y 24607560-24639207 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 testis: 2.1 kidney: 0.1 -EMILIN3 C20orf130, dJ620E11.4, EMILIN5 ENSG00000183798 Elastin microfibril interfacer 3 20 41359966-41366827 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044034, HPA059912 Approved Tissue enhanced 0 epididymis: 59.6 seminal vesicle: 13.4 -OLFML1 UNQ564 ENSG00000183801 Olfactomedin-like 1 11 7485388-7511377 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039735 Uncertain Mixed ovary: 60.0 -FAM162B bA86F4.2, C6orf189 ENSG00000183807 Family with sequence similarity 162, member B 6 116752197-116765723 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036112, HPA060342 Uncertain Tissue enhanced 0 placenta: 93.2 lung: 27.0 -RBM12B ENSG00000183808 RNA binding motif protein 12B 8 93729356-93741017 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024398, HPA053050 Uncertain Approved Nucleoplasm Expressed in all testis: 33.1 -CCR4 CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5 ENSG00000183813 Chemokine (C-C motif) receptor 4 3 32951574-32956349 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA031613 Approved Tissue enhanced 0 appendix: 11.8 urinary bladder: 9.2 -LIN9 TGS ENSG00000183814 Lin-9 DREAM MuvB core complex component 1 226231149-226309869 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030241 Uncertain Supported Nucleoplasm Mixed testis: 16.8 -BTBD9 dJ322I12.1, KIAA1880 ENSG00000183826 BTB (POZ) domain containing 9 6 38168451-38640148 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041930 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 38.2 -NUDT14 UGPP ENSG00000183828 Nudix (nucleoside diphosphate linked moiety X)-type motif 14 14 105172938-105181323 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046755, HPA058759 Approved Approved Nucleoli
Microtubules Expressed in all cerebral cortex: 24.8 -ANKRD45 CT117, FLJ45235 ENSG00000183831 Ankyrin repeat domain 45 1 173609561-173669862 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031655, HPA031656, HPA031657 Supported Tissue enhanced 0 fallopian tube: 34.5;parathyroid gland: 22.5;testis: 36.2 cerebral cortex: 7.2 -MAATS1 AAT1, AAT1alpha, C3orf15, CaM-IP2, SPATA26 ENSG00000183833 MYCBP-associated, testis expressed 1 3 119703022-119767102 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 fallopian tube: 22.4;testis: 15.8 thyroid gland: 7.8 -PNMA3 MA3, MA5, MGC132756, MGC132758 ENSG00000183837 Paraneoplastic Ma antigen 3 X 153056409-153060467 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047920 Approved Group enriched 13 cerebral cortex: 15.4;epididymis: 44.8;testis: 12.3 fallopian tube: 1.8 -GPR39 ENSG00000183840 G protein-coupled receptor 39 2 132416574-132646559 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022111 Approved Tissue enhanced 0 parathyroid gland: 17.7 colon: 6.2 -FAM3B 2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44 ENSG00000183844 Family with sequence similarity 3, member B 21 41304212-41357431 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015885, HPA029777 Approved Approved Vesicles Tissue enhanced 0 duodenum: 166.7;small intestine: 170.3 stomach: 124.7 -ZNF730 ENSG00000183850 Zinc finger protein 730 19 23075210-23147219 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 9.5 ovary: 3.1 -KIRREL NEPH1 ENSG00000183853 Kin of IRRE like (Drosophila) 1 157993273-158100262 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030458 Approved Mixed placenta: 46.8 -IQGAP3 ENSG00000183856 IQ motif containing GTPase activating protein 3 1 156525405-156572604 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030142, HPA030143 Uncertain Approved Nucleus
Nucleoli Mixed bone marrow: 9.9 -CNGA2 CNCA, CNCA1, CNG2, FLJ46312, OCNC1, OCNCa, OCNCALPHA ENSG00000183862 Cyclic nucleotide gated channel alpha 2 X 151738451-151745304 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level No evidence Evidence at transcript level Evidence at protein level HPA015065 Uncertain Not detected testis: 0.4 -TOB2 bK223H9, TOB4, TOBL, TROB2 ENSG00000183864 Transducer of ERBB2, 2 22 41433492-41447023 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016603, HPA054112 Approved Approved Cytosol Expressed in all parathyroid gland: 59.1 -SCN5A CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1 ENSG00000183873 Sodium channel, voltage gated, type V alpha subunit 3 38548057-38649673 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 18 heart muscle: 26.9 cervix: 1.5 -ARSI FLJ16069, SPG66 ENSG00000183876 Arylsulfatase family, member I 5 150296343-150339307 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038386, HPA038398 Uncertain Approved Golgi apparatus Mixed skin: 5.7 -UTY KDM6AL ENSG00000183878 Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked Y 13248379-13480673 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000568, HPA001165 Supported Approved Nucleoli Mixed prostate: 12.9 -C1orf64 ERRF, MGC24047 ENSG00000183888 Chromosome 1 open reading frame 64 1 16004236-16008807 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026676 Uncertain Approved Nucleoplasm Tissue enhanced 0 breast: 7.0 cervix: 3.7 -AC138969.4 ENSG00000183889 16 16317444-16350590 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level HPA053611 Approved Uncertain Nucleoplasm Expressed in all skin: 115.8 -TTC32 ENSG00000183891 Tetratricopeptide repeat domain 32 2 19896643-19901986 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036024 Approved Approved Nucleoplasm
Mitochondria Expressed in all epididymis: 36.4 -LRRC55 FLJ45686 ENSG00000183908 Leucine rich repeat containing 55 11 57181747-57191717 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA014053 Uncertain Tissue enhanced 0 cerebral cortex: 6.6 lymph node: 2.4 -DNAH2 DNHD3, FLJ46675, KIAA1503 ENSG00000183914 Dynein, axonemal, heavy chain 2 17 7717354-7833744 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA067103 Supported Approved Microtubules Group enriched 8 fallopian tube: 20.7;parathyroid gland: 28.1;testis: 11.0 placenta: 2.5 -SH2D1A DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD ENSG00000183918 SH2 domain containing 1A X 124227868-124373197 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lymph node: 36.8;spleen: 17.7 tonsil: 13.7 -SDR42E2 ENSG00000183921 Short chain dehydrogenase/reductase family 42E, member 2 16 22165583-22191754 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA061278 Uncertain Tissue enhanced 0 fallopian tube: 1.1;testis: 1.0 parathyroid gland: 0.2 -PRKX PKX1 ENSG00000183943 Protein kinase, X-linked X 3604370-3713608 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015324 Supported Supported Nucleus Tissue enhanced 0 thyroid gland: 57.8 fallopian tube: 31.6 -SETD8 KMT5A, PR-Set7, SET07, SET8 ENSG00000183955 SET domain containing (lysine methyltransferase) 8 12 123383773-123409358 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA064495 Supported Nucleus Expressed in all thyroid gland: 36.1 -KCNH8 elk3, Kv12.1 ENSG00000183960 Potassium channel, voltage gated eag related subfamily H, member 8 3 19148454-19535646 Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 4.8 adrenal gland: 2.3 -SMTN ENSG00000183963 Smoothelin 22 31064105-31104757 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001721, HPA051778, HPA058590 Supported Validated Nucleoplasm
Actin filaments Expressed in all seminal vesicle: 252.4 -NPW PPL8 ENSG00000183971 Neuropeptide W 16 2009926-2020755 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA064874 Approved Tissue enhanced 0 liver: 3.6 stomach: 1.8 -PP2D1 C3orf48, FLJ25449 ENSG00000183977 Protein phosphatase 2C-like domain containing 1 3 19979961-20012330 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA036870, HPA066083 Supported Uncertain Nucleoplasm
Intermediate filaments Tissue enriched 11 testis: 12.8 bone marrow: 1.2 -COA3 CCDC56, HSPC009, MITRAC12 ENSG00000183978 Cytochrome c oxidase assembly factor 3 17 42795147-42798704 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031966 Approved Supported Mitochondria Expressed in all epididymis: 210.1 -NPB PPL7, PPNPB ENSG00000183979 Neuropeptide B 17 81900745-81902905 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA057419 Uncertain Tissue enhanced 0 epididymis: 3.0 cerebral cortex: 0.6 -ST6GALNAC3 SIAT7C ENSG00000184005 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 1 76074719-76634601 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA054566, HPA055399 Uncertain Supported Nucleoplasm Tissue enhanced 0 thyroid gland: 22.3 parathyroid gland: 11.0 -PTP4A2 HU-PP-1, OV-1, PRL-2, ptp-IV1a, PTP4A, PTPCAAX2 ENSG00000184007 Protein tyrosine phosphatase type IVA, member 2 1 31906421-31944856 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003281, CAB011204 Uncertain Expressed in all thyroid gland: 278.8 -ACTG1 ACTG, DFNA20, DFNA26 ENSG00000184009 Actin gamma 1 17 81509971-81523847 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041264, HPA041271 Approved Expressed in all ovary: 2398.3 -TMPRSS2 PRSS10 ENSG00000184012 Transmembrane protease, serine 2 21 41464551-41531116 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034493, HPA035787 Supported Supported Nucleoplasm
Cell Junctions Tissue enhanced 0 prostate: 495.7 stomach: 142.5 -DENND5A FLJ22354, FLJ33829, FLJ43455, KIAA1091, RAB6IP1 ENSG00000184014 DENN/MADD domain containing 5A 11 9138825-9265390 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052923, HPA055009 Uncertain Approved Golgi apparatus
Vesicles Expressed in all cerebral cortex: 127.2 -OR2T10 ENSG00000184022 Olfactory receptor, family 2, subfamily T, member 10 1 248592830-248593768 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052019 Uncertain Tissue enriched 13 kidney: 7.1 prostate: 0.5 -DSCR4 DCRB ENSG00000184029 Down syndrome critical region 4 21 37951425-38121360 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018460 Uncertain Group enriched 18 placenta: 2.0;testis: 1.4 epididymis: 0.0 -KRTAP20-2 KAP20.2 ENSG00000184032 Keratin associated protein 20-2 21 30635236-30635619 Predicted intracellular proteins No evidence No evidence No evidence Not detected skin: 0.6 -CTAG1B CT6.1, CTAG, CTAG1, ESO1, LAGE2A, LAGE2B, NY-ESO-1 ENSG00000184033 Cancer/testis antigen 1B X 154617604-154619282 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB015453 Supported Tissue enriched 46 testis: 5.5 spleen: 0.1 -DIABLO DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC ENSG00000184047 Diablo, IAP-binding mitochondrial protein 12 122207662-122227534 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001825, CAB003857, CAB016688 Supported Validated Mitochondria Expressed in all testis: 94.5 -VPS33B FLJ14848 ENSG00000184056 Vacuolar protein sorting 33 homolog B (yeast) 15 90998416-91022603 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040415 Approved Expressed in all cerebral cortex: 16.2 -TBX1 CATCH22, VCF ENSG00000184058 T-box 1 22 19756703-19783593 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029330 Approved Nuclear bodies
Cytoplasmic bodies Tissue enhanced 0 skeletal muscle: 23.0 testis: 10.5 -ADAP2 CENTA2 ENSG00000184060 ArfGAP with dual PH domains 2 17 30906344-30959322 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed spleen: 29.8 -UQCR10 HSPC051, QCR9, UCCR7.2, UCRC ENSG00000184076 Ubiquinol-cytochrome c reductase, complex III subunit X 22 29767369-29770413 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all heart muscle: 187.7 -FAM120C CXorf17, FLJ20506, ORF34 ENSG00000184083 Family with sequence similarity 120C X 54068324-54183281 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047677 Uncertain Approved Nuclear speckles Mixed cerebral cortex: 9.6 -TRIML1 FLJ36180, RNF209 ENSG00000184108 Tripartite motif family-like 1 4 188139419-188147743 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 147 testis: 14.7 epididymis: 0.0 -EIF3C eIF3-p110, eIF3c, EIF3S8 ENSG00000184110 Eukaryotic translation initiation factor 3, subunit C 16 28688558-28735730 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034045, HPA047097, HPA049495, HPA050112 Supported Supported Cytosol Expressed in all parathyroid gland: 565.2 -CLDN5 AWAL, BEC1, CPETRL1, TMVCF ENSG00000184113 Claudin 5 22 19523024-19527545 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB002607 Approved Tissue enhanced 0 adipose tissue: 128.2 lung: 53.8 -NIPSNAP1 ENSG00000184117 Nipsnap homolog 1 (C. elegans) 22 29554808-29581337 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059227 Uncertain Expressed in all liver: 134.2 -OR4F6 OR4F12 ENSG00000184140 Olfactory receptor, family 4, subfamily F, member 6 15 101805699-101806686 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -CNTN2 AXT, TAG-1, TAX, TAX1 ENSG00000184144 Contactin 2 (axonal) 1 205043197-205078499 Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001397, HPA012497 Approved Tissue enriched 12 cerebral cortex: 79.8 testis: 6.9 -SPRR4 ENSG00000184148 Small proline-rich protein 4 1 152970666-152972574 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA055963 Supported Tissue enriched 6 skin: 48.3 breast: 7.8 -LRTOMT CFAP111, COMT2, DFNB63, LRRC51 ENSG00000184154 Leucine rich transmembrane and O-methyltransferase domain containing 11 72080331-72110782 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039949 Approved Approved Nucleoli
Microtubules Expressed in all testis: 137.8 -OR10J5 ENSG00000184155 Olfactory receptor, family 10, subfamily J, member 5 1 159535078-159536007 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected liver: 0.1 -KCNQ3 EBN2, Kv7.3 ENSG00000184156 Potassium channel, voltage gated KQT-like subfamily Q, member 3 8 132120859-132480953 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 14 cerebral cortex: 26.9 adrenal gland: 1.9 -ADRA2C ADRA2L2, ADRA2RL2, ADRARL2 ENSG00000184160 Adrenoceptor alpha 2C 4 3766348-3768526 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057688 Uncertain Tissue enhanced 0 cervix, uterine: 21.0;endometrium: 26.0;seminal vesicle: 26.7 fallopian tube: 7.9 -NR2C2AP TRA16 ENSG00000184162 Nuclear receptor 2C2-associated protein 19 19201416-19203424 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042054, HPA055653 Approved Validated Nucleoplasm Expressed in all fallopian tube: 23.9 -FAM132A C1QDC2, C1QTNF12, CTRP12, MGC105127 ENSG00000184163 Family with sequence similarity 132, member A 1 1242446-1246722 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA024107 Approved Approved Vesicles Tissue enhanced 0 duodenum: 7.1;small intestine: 7.5 colon: 2.2 -CRELD2 MGC11256 ENSG00000184164 Cysteine-rich with EGF-like domains 2 22 49918167-49927540 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000603, CAB025604 Approved Expressed in all thyroid gland: 94.0 -OR1D2 OLFR1, OR17-4 ENSG00000184166 Olfactory receptor, family 1, subfamily D, member 2 17 3092058-3092996 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.2 -SCFD2 FLJ39514, STXBP1L1 ENSG00000184178 Sec1 family domain containing 2 4 52872982-53366075 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036526, HPA036527 Supported Approved Nucleus Expressed in all cerebral cortex: 14.7 -UBE2F NCE2 ENSG00000184182 Ubiquitin-conjugating enzyme E2F (putative) 2 237966827-238042782 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037444 Approved Approved Cytosol Expressed in all epididymis: 62.7 -KCNJ12 hIRK1, IRK2, KCNJN1, Kir2.2, Kir2.2v ENSG00000184185 Potassium channel, inwardly rectifying subfamily J, member 12 17 21376197-21419872 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027021 Approved Uncertain Nucleoplasm
Golgi apparatus
Cytosol Group enriched 5 parathyroid gland: 18.9;skeletal muscle: 23.1 heart muscle: 3.9 -GPR173 SREB3 ENSG00000184194 G protein-coupled receptor 173 X 53049091-53080615 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA003905 Approved Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 19.1 ovary: 9.0 -PPP1R2 IPP2 ENSG00000184203 Protein phosphatase 1, regulatory (inhibitor) subunit 2 3 195514425-195543386 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043729, HPA059420 Uncertain Validated Nucleoplasm
Cytosol Expressed in all testis: 54.6 -TSPYL2 CDA1, CINAP, CTCL, DENTT, HRIHFB2216, SE20-4, TSPX ENSG00000184205 TSPY-like 2 X 53082367-53088540 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044133 Approved Expressed in all ovary: 144.1 -GOLGA6L4 ENSG00000184206 Golgin A6 family-like 4 15 84235773-84245368 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Mixed ovary: 7.2 -PGP ENSG00000184207 Phosphoglycolate phosphatase 16 2211997-2214807 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043096, HPA046739 Approved Approved Nuclear bodies Expressed in all testis: 28.2 -C22orf46 CTA-216E10.6, FLJ23584 ENSG00000184208 Chromosome 22 open reading frame 46 22 41688939-41698136 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052741, HPA057048 Uncertain Approved Nucleus
Nucleoli Mixed parathyroid gland: 17.4 -SNRNP35 U1SNRNPBP ENSG00000184209 Small nuclear ribonucleoprotein 35kDa (U11/U12) 12 123457641-123473154 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059145, HPA067031 Supported Supported Nucleoli Expressed in all parathyroid gland: 33.9 -DGAT2L6 DC3, FLJ25989 ENSG00000184210 Diacylglycerol O-acyltransferase 2-like 6 X 70177483-70205545 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 23 breast: 2.8;skin: 1.6 epididymis: 0.0 -IRAK1 IRAK, pelle ENSG00000184216 Interleukin-1 receptor-associated kinase 1 X 154010500-154019980 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004461, HPA054476 Supported Supported Nucleus
Cytosol Expressed in all appendix: 52.6 -CMSS1 C3orf26, MGC4308 ENSG00000184220 Cms1 ribosomal small subunit homolog (yeast) 3 99817834-100178603 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042820 Uncertain Approved Nucleus
Nuclear membrane
Nucleoli
Mitochondria Expressed in all testis: 56.0 -OLIG1 BHLHB6, bHLHe21 ENSG00000184221 Oligodendrocyte transcription factor 1 21 33070144-33072420 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 103 cerebral cortex: 143.0 kidney: 1.3 -PCDH9 ENSG00000184226 Protocadherin 9 13 66302834-67230445 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015581 Approved Nucleoplasm
Centrosome Tissue enriched 11 cerebral cortex: 69.0 seminal vesicle: 6.0 -ACOT1 ACH2, CTE-1, LACH2 ENSG00000184227 Acyl-CoA thioesterase 1 14 73537114-73543794 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043705 Approved Approved Mitochondria Mixed smooth muscle: 29.0 -OAF MGC52117 ENSG00000184232 Out at first homolog 11 120210767-120230332 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047412 Uncertain Approved Nucleus Expressed in all liver: 80.2 -ALDH1A3 ALDH6, RALDH3 ENSG00000184254 Aldehyde dehydrogenase 1 family, member A3 15 100877714-100916626 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046271, HPA064749 Approved Validated Nucleus
Cytosol Tissue enhanced 0 prostate: 209.6 adipose tissue: 74.0 -CDR1 CDR, CDR34, CDR62A ENSG00000184258 Cerebellar degeneration-related protein 1, 34kDa X 140782405-140784871 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA073147 Approved Nucleoplasm
Golgi apparatus
Centrosome Tissue enhanced 0 cerebral cortex: 48.5 skin: 12.1 -HIST2H2AC H2A, H2A/q, H2AFQ ENSG00000184260 Histone cluster 2, H2ac 1 149886975-149887364 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enriched 10 bone marrow: 23.8 adrenal gland: 2.4 -KCNK12 K2p12.1, THIK-2, THIK2 ENSG00000184261 Potassium channel, two pore domain subfamily K, member 12 2 47516581-47570939 Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 16 cerebral cortex: 5.3 testis: 0.3 -HIST2H2AB ENSG00000184270 Histone cluster 2, H2ab 1 149887524-149887916 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011483, HPA041189 Supported Approved Nucleus Tissue enriched 6 bone marrow: 4.0 prostate: 0.6 -POU6F1 BRN5, MPOU, TCFB1 ENSG00000184271 POU class 6 homeobox 1 12 51186936-51217693 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA047021, HPA050411 Supported Supported Nuclear bodies
Actin filaments Mixed cerebral cortex: 25.2 -DEFB108B ENSG00000184276 Defensin, beta 108B 11 71833200-71837710 Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level HPA042588 Uncertain Not detected epididymis: 0.0 -TM2D3 BLP2, FLJ22604 ENSG00000184277 TM2 domain containing 3 15 101621444-101652391 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054064 Uncertain Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 97.5 -TSSC4 ENSG00000184281 Tumor suppressing subtransferable candidate 4 11 2400488-2403878 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041801, HPA058763 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 56.6 -TACSTD2 EGP-1, GA733-1, M1S1, TROP2 ENSG00000184292 Tumor-associated calcium signal transducer 2 1 58575423-58577773 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043104, HPA055067, CAB072852 Supported Supported Nucleoli
Vesicles
Plasma membrane Tissue enhanced 0 esophagus: 315.1 skin: 210.1 -CLECL1 DCAL1 ENSG00000184293 C-type lectin-like 1 12 9715860-9733299 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 lymph node: 29.1;spleen: 23.2;tonsil: 29.6 appendix: 13.7 -SIX6 OPTX2, Six9 ENSG00000184302 SIX homeobox 6 14 60508951-60512850 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001403 Supported Approved Nucleoplasm Not detected testis: 0.1 -PRKD1 PKC-mu, PKCM, PKD, PRKCM ENSG00000184304 Protein kinase D1 14 29576479-30191898 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018367, HPA029834 Uncertain Supported Plasma membrane
Cytosol Tissue enhanced 0 parathyroid gland: 49.5 prostate: 29.0 -CCSER1 FAM190A, KIAA1680 ENSG00000184305 Coiled-coil serine-rich protein 1 4 90127535-91601913 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041880, HPA054709 Uncertain Tissue enhanced 0 testis: 4.6 adrenal gland: 1.7 -ZDHHC23 MGC42530 ENSG00000184307 Zinc finger, DHHC-type containing 23 3 113947901-113965401 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA016808 Uncertain Approved Nucleus Tissue enhanced 0 testis: 15.3 cerebral cortex: 6.2 -MROH7 C1orf175, FLJ46354, HEATR8 ENSG00000184313 Maestro heat-like repeat family member 7 1 54641754-54710266 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 30 testis: 49.5 ovary: 1.6 -OR51J1 OR51J1P, OR51J2 ENSG00000184321 Olfactory receptor, family 51, subfamily J, member 1 (gene/pseudogene) 11 5402597-5403547 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA017605 Uncertain Not detected epididymis: 0.1 -S100A7A S100A15, S100A7f, S100A7L1 ENSG00000184330 S100 calcium binding protein A7A 1 153416524-153423225 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006997 Supported Group enriched 8 skin: 1.9;tonsil: 5.6 testis: 0.4 -SRPK3 MSSK1, STK23 ENSG00000184343 SRSF protein kinase 3 X 153776412-153785732 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 5 heart muscle: 28.3;skeletal muscle: 73.6 prostate: 9.8 -GDF3 ENSG00000184344 Growth differentiation factor 3 12 7689782-7695776 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018468 Uncertain Tissue enhanced 0 kidney: 1.1;spleen: 1.1 testis: 0.8 -IQCF2 ENSG00000184345 IQ motif containing F2 3 51861629-51863424 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 97 testis: 9.7 epididymis: 0.0 -SLIT3 MEGF5, SLIL2, Slit-3, SLIT1, slit2 ENSG00000184347 Slit guidance ligand 3 5 168661733-169301129 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051630 Approved Approved Cell Junctions Mixed parathyroid gland: 98.0 -EFNA5 AF1, EPLG7, LERK7 ENSG00000184349 Ephrin-A5 5 107376889-107670895 Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013282, HPA054047 Approved Approved Vesicles
Cytosol Mixed cervix: 17.1 -MRGPRE GPR167, mrgE ENSG00000184350 MAS-related GPR, member E 11 3227698-3232386 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046556 Uncertain Tissue enhanced 0 cervix, uterine: 1.0 spleen: 0.6 -KRTAP19-1 KAP19.1 ENSG00000184351 Keratin associated protein 19-1 21 30479699-30480344 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected prostate: 0.1 -HIST1H1B H1.5, H1b, H1F5, H1s-3 ENSG00000184357 Histone cluster 1, H1b 6 27866849-27867529 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012241, HPA055907 Uncertain Supported Nucleoplasm Tissue enhanced 0 bone marrow: 6.2;lymph node: 2.6 urinary bladder: 0.9 -SPATA32 AEP2, C17orf46, FLJ25414, TEX34, VAD1.2 ENSG00000184361 Spermatogenesis associated 32 17 45254393-45262112 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA024549 Uncertain Tissue enriched 84 testis: 40.8 duodenum: 0.4 -PKP3 ENSG00000184363 Plakophilin 3 11 392614-404908 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012993, HPA062937 Supported Validated Nucleoplasm
Cell Junctions
Cytosol Tissue enhanced 0 esophagus: 98.6;skin: 148.5 duodenum: 32.2 -MAP7D2 FLJ14503 ENSG00000184368 MAP7 domain containing 2 X 20006713-20116917 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051508, HPA059537 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 49.3;epididymis: 45.0 testis: 18.3 -CSF1 M-CSF, MCSF, MGC31930 ENSG00000184371 Colony stimulating factor 1 (macrophage) 1 109910242-109930992 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA076624 Supported Plasma membrane Expressed in all adipose tissue: 66.1 -COLEC10 CL-L1 ENSG00000184374 Collectin sub-family member 10 (C-type lectin) 8 118995452-119106582 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 8 liver: 51.1;placenta: 25.7 thyroid gland: 4.9 -ACTRT3 ARPM1 ENSG00000184378 Actin-related protein T3 3 169766921-169769895 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035817, HPA035818 Approved Approved Nucleoplasm Tissue enriched 21 testis: 60.8 fallopian tube: 2.9 -PLA2G6 iPLA2, iPLA2beta, NBIA2, PARK14, PNPLA9 ENSG00000184381 Phospholipase A2, group VI (cytosolic, calcium-independent) 22 38111495-38205690 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001171 Approved Approved Microtubule organizing center
Cytosol Expressed in all testis: 60.3 -MAML2 KIAA1819, MAM3 ENSG00000184384 Mastermind-like transcriptional coactivator 2 11 95976598-96343180 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035223 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Mixed placenta: 17.4 -PABPC1L2B RBM32B ENSG00000184388 Poly(A) binding protein, cytoplasmic 1-like 2B X 73003517-73005713 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041573 Approved Group enriched 5 cerebral cortex: 8.8;prostate: 4.5 testis: 1.2 -A3GALT2 A3GALT2P, IGBS3S ENSG00000184389 Alpha 1,3-galactosyltransferase 2 1 33306766-33321098 Predicted membrane proteins No evidence No evidence Not detected testis: 0.8 -OR4N5 ENSG00000184394 Olfactory receptor, family 4, subfamily N, member 5 14 20143736-20144662 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Not detected epididymis: 0.0 -SS18L1 KIAA0693 ENSG00000184402 Synovial sarcoma translocation gene on chromosome 18-like 1 20 62143795-62182484 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011827, HPA059046 Approved Supported Nucleoplasm
Cytosol Expressed in all skin: 23.7 -KCND2 KIAA1044, Kv4.2, RK5 ENSG00000184408 Potassium channel, voltage gated Shal related subfamily D, member 2 7 120273668-120750331 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029068 Approved Tissue enhanced 0 cerebral cortex: 20.8 gallbladder: 6.9 -TOP1MT ENSG00000184428 Topoisomerase (DNA) I, mitochondrial 8 143304384-143359979 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001915, HPA021542 Approved Supported Mitochondria Expressed in all testis: 41.2 -COPB2 beta'-COP, betaprime-COP ENSG00000184432 Coatomer protein complex, subunit beta 2 (beta prime) 3 139355600-139389732 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036867, HPA058180 Approved Approved Cytosol Expressed in all parathyroid gland: 171.6 -LRRC19 FLJ21302 ENSG00000184434 Leucine rich repeat containing 19 9 26993136-27005693 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 8 colon: 36.8;duodenum: 24.4;gallbladder: 9.5;kidney: 45.4;rectum: 36.2;small intestine: 35.4 appendix: 3.7 -THAP7 MGC10963 ENSG00000184436 THAP domain containing 7 22 20999104-21002196 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA003083 Approved Approved Nucleus
Vesicles Expressed in all testis: 20.4 -KNTC1 KIAA0166, ROD ENSG00000184445 Kinetochore associated 1 12 122527246-122626396 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025241 Approved Supported Plasma membrane
Cytosol Tissue enhanced 0 testis: 43.2 bone marrow: 27.2 -CCR10 GPR2 ENSG00000184451 Chemokine (C-C motif) receptor 10 17 42678889-42683917 Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB011684, HPA048007, HPA069188 Uncertain Supported Endoplasmic reticulum Mixed adipose tissue: 4.5 -NCMAP C1orf130, FLJ42528, MP11 ENSG00000184454 Noncompact myelin associated protein 1 24556111-24609328 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA013656 Uncertain Tissue enhanced 0 gallbladder: 11.5 thyroid gland: 7.1 -BPIFC BPIL2, dJ149A16.7 ENSG00000184459 BPI fold containing family C 22 32413847-32464484 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037665, HPA043306 Uncertain Tissue enriched 19 skin: 75.7 breast: 4.0 -WDR27 MGC43690 ENSG00000184465 WD repeat domain 27 6 169457212-169702048 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037497, HPA037498 Uncertain Validated Nucleoplasm Mixed testis: 15.8 -TXNRD2 TR, TR3, TRXR2 ENSG00000184470 Thioredoxin reductase 2 22 19875517-19941992 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002007, HPA003323 Supported Supported Mitochondria
Cytosol Expressed in all adrenal gland: 34.4 -C1QTNF8 CTRP8, UNQ5829 ENSG00000184471 C1q and tumor necrosis factor related protein 8 16 1090005-1096244 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA056438 Uncertain Not detected fallopian tube: 0.7 -OR56A3 OR56A3P, OR56A6 ENSG00000184478 Olfactory receptor, family 56, subfamily A, member 3 11 5947340-5948361 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.1 -FOXO4 AFX1, MLLT7 ENSG00000184481 Forkhead box O4 X 71096197-71103535 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039560, HPA040232 Approved Supported Nuclear speckles
Cytosol Expressed in all placenta: 171.9 -POU3F2 BRN2, OCT7, OTF7, POUF3 ENSG00000184486 POU class 3 homeobox 2 6 98834592-98839490 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047081, HPA056261 Approved Supported Nucleus Tissue enriched 67 cerebral cortex: 20.4 testis: 0.3 -PTP4A3 PRL-3, PRL-R, PRL3 ENSG00000184489 Protein tyrosine phosphatase type IVA, member 3 8 141391993-141432454 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003281 Uncertain Group enriched 7 heart muscle: 75.4;skeletal muscle: 153.1 smooth muscle: 16.8 -FOXD4L1 FOXD5 ENSG00000184492 Forkhead box D4-like 1 2 113498665-113501155 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA012836 Uncertain Approved Nucleus Not detected testis: 0.7 -TMEM255B FAM70B, MGC20579 ENSG00000184497 Transmembrane protein 255B 13 113759240-113816995 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA043334 Approved Approved Nucleoplasm Mixed lung: 8.3 -PROS1 PROS ENSG00000184500 Protein S (alpha) 3 93873033-93974066 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007724, HPA023974 Supported Tissue enhanced 0 liver: 177.6 heart muscle: 75.3 -GAST GAS ENSG00000184502 Gastrin 17 41712326-41715969 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB000038 Supported Tissue enriched 197 stomach: 11343.0 duodenum: 57.5 -NUTM1 C15orf55, DKFZp434O192, FAM22H, NUT ENSG00000184507 NUT midline carcinoma, family member 1 15 34343315-34357737 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040421 Approved Tissue enriched 78 testis: 22.5 skin: 0.2 -HDDC3 MGC45386 ENSG00000184508 HD domain containing 3 15 90929964-90932569 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040895 Approved Approved Nucleoplasm
Cytosol Expressed in all adrenal gland: 16.3 -BEX5 NGFRAP1L1 ENSG00000184515 Brain expressed, X-linked 5 X 102153708-102156057 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059058 Approved Tissue enhanced 0 cerebral cortex: 96.4 epididymis: 34.2 -ZFP1 FLJ34243, ZNF475 ENSG00000184517 ZFP1 zinc finger protein 16 75148492-75172236 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044916, HPA062910 Uncertain Approved Nucleus Mixed cerebral cortex: 25.1 -CEND1 BM88, FLJ90066 ENSG00000184524 Cell cycle exit and neuronal differentiation 1 11 787104-790123 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042527 Supported Approved Mitochondria Tissue enriched 16 cerebral cortex: 114.3 adrenal gland: 7.1 -C6orf58 ENSG00000184530 Chromosome 6 open reading frame 58 6 127519455-127591817 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036263, HPA041449 Supported Group enriched 21 duodenum: 620.9;salivary gland: 164.6;stomach: 319.1 esophagus: 17.2 -DHRS7C SDR32C2 ENSG00000184544 Dehydrogenase/reductase (SDR family) member 7C 17 9771434-9791297 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 16 heart muscle: 71.2;skeletal muscle: 122.8 esophagus: 5.9 -DUSP8 C11orf81, FLJ42958, HB5, HVH-5 ENSG00000184545 Dual specificity phosphatase 8 11 1554044-1571920 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA020071 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 5.1 smooth muscle: 2.2 -SOCS3 CIS3, Cish3, SOCS-3, SSI-3 ENSG00000184557 Suppressor of cytokine signaling 3 17 78356778-78360077 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB012220, HPA068569 Approved Approved Cytosol Mixed adipose tissue: 319.2 -C17orf74 ENSG00000184560 Chromosome 17 open reading frame 74 17 7425615-7427568 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023649 Uncertain Tissue enriched 618 testis: 61.7 adipose tissue: 0.0 -SLITRK6 FLJ22774 ENSG00000184564 SLIT and NTRK-like family, member 6 13 85792790-85799488 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014491, HPA014513 Uncertain Supported Plasma membrane Tissue enhanced 0 urinary bladder: 20.4 salivary gland: 11.8 -PIWIL3 HIWI3 ENSG00000184571 Piwi-like RNA-mediated gene silencing 3 22 24719034-24774720 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA061955 Uncertain Tissue enriched 13 testis: 1.7 skin: 0.1 -LPAR5 GPR92, GPR93, KPG_010, LPA5 ENSG00000184574 Lysophosphatidic acid receptor 5 12 6618835-6636447 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA013170 Approved Mixed tonsil: 11.0 -XPOT XPO3 ENSG00000184575 Exportin, tRNA 12 64404350-64451127 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048067, HPA057602 Validated Nucleoplasm
Cytosol Expressed in all thyroid gland: 82.9 -TMEM173 FLJ38577, NET23 ENSG00000184584 Transmembrane protein 173 5 139475534-139482935 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038116, HPA038534 Supported Supported Cytosol Expressed in all lung: 70.2 -PDE4B DPDE4 ENSG00000184588 Phosphodiesterase 4B, cAMP-specific 1 65792514-66374579 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003005 Uncertain Mixed cerebral cortex: 67.2 -FAM19A3 TAFA-3 ENSG00000184599 Family with sequence similarity 19 (chemokine (C-C motif)-like), member A3 1 112720419-112727235 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055927 Approved Group enriched 16 adrenal gland: 20.0;testis: 8.7 epididymis: 0.9 -C14orf180 C14orf77, NRAC ENSG00000184601 Chromosome 14 open reading frame 180 14 104579684-104590515 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 19 adipose tissue: 34.6;heart muscle: 28.7 adrenal gland: 1.6 -SNN ENSG00000184602 Stannin 16 11668414-11679159 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA011055 Approved Approved Cytosol Expressed in all cerebral cortex: 151.1 -KCNH7 erg3, HERG3, Kv11.3 ENSG00000184611 Potassium channel, voltage gated eag related subfamily H, member 7 2 162371407-162838730 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA018039 Uncertain Tissue enriched 6 cerebral cortex: 4.7 testis: 0.7 -NELL2 NRP2 ENSG00000184613 Neural EGFL like 2 12 44508275-44921848 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035714, HPA035715 Uncertain Approved Vesicles Tissue enhanced 0 cerebral cortex: 204.7;fallopian tube: 95.3 prostate: 40.8 -KRBA2 ENSG00000184619 KRAB-A domain containing 2 17 8368637-8376711 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA022849 Approved Uncertain Nucleoplasm Mixed parathyroid gland: 7.7 -MED12 CAGH45, FGS1, HOPA, KIAA0192, OKS, OPA1, TNRC11, TRAP230 ENSG00000184634 Mediator complex subunit 12 X 71118556-71142454 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003184, HPA003185 Supported Approved Nucleoplasm Expressed in all spleen: 27.1 -ZNF93 FLJ12488, HPF34, TF34, ZNF505 ENSG00000184635 Zinc finger protein 93 19 19900913-19935575 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed thyroid gland: 14.2 -SEPT9 AF17q25, KIAA0991, MSF, MSF1, PNUTL4, SeptD1 ENSG00000184640 Septin 9 17 77280569-77500596 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042564, HPA050627 Approved Validated Actin filaments Expressed in all lymph node: 272.5 -PRSS55 CT153, T-SP1, UNQ9391 ENSG00000184647 Protease, serine, 55 8 10525546-10554166 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 93 testis: 26.1 epididymis: 0.2 -ODF4 CT136, OPPO1 ENSG00000184650 Outer dense fiber of sperm tails 4 17 8339864-8346046 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 56 testis: 21.1 esophagus: 0.3 -FOXD4L4 bA460E7.2, FOXD4L2 ENSG00000184659 Forkhead box D4-like 4 9 65736555-65738784 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA012836 Uncertain Approved Nucleus Not detected fallopian tube: 0.1 -CDCA2 PPP1R81, Repo-Man ENSG00000184661 Cell division cycle associated 2 8 25458997-25507920 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026293, HPA030049 Approved Validated Nucleoplasm Tissue enriched 6 testis: 31.3 tonsil: 5.5 -RALYL HNRPCL3 ENSG00000184672 RALY RNA binding protein-like 8 84182787-84921844 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055868, HPA059112 Supported Supported Nucleoplasm Tissue enhanced 0 adrenal gland: 26.2;cerebral cortex: 49.3;kidney: 19.6 gallbladder: 8.2 -AMER1 FAM123B, FLJ39827, RP11-403E24.2, WTX ENSG00000184675 APC membrane recruitment protein 1 X 64185117-64205744 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065214, HPA065265 Approved Supported Nuclear bodies
Vesicles
Plasma membrane Mixed ovary: 7.7 -ZBTB40 KIAA0478, ZNF923 ENSG00000184677 Zinc finger and BTB domain containing 40 1 22451851-22531157 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042386 Approved Nucleus Expressed in all parathyroid gland: 20.5 -HIST2H2BE H2B, H2B.1, H2B/q, H2BFQ ENSG00000184678 Histone cluster 2, H2be 1 149842204-149886652 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Expressed in all prostate: 112.0 -PRR33 C11orf89, LOC728008 ENSG00000184682 Proline rich 33 11 1889145-1890854 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA040293 Uncertain Tissue enhanced 0 skeletal muscle: 15.5 spleen: 12.6 -CLDN6 ENSG00000184697 Claudin 6 16 3014712-3020071 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 placenta: 1.0;testis: 1.8 parathyroid gland: 0.3 -OR51M1 ENSG00000184698 Olfactory receptor, family 51, subfamily M, member 1 11 5389399-5390379 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA056773 Uncertain Not detected epididymis: 0.0 -SEPT5 H5, HCDCREL-1, PNUTL1 ENSG00000184702 Septin 5 22 19714464-19724772 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016120, HPA029095, HPA063885 Supported Approved Nucleoplasm
Actin filaments
Cytosol Expressed in all parathyroid gland: 378.7 -EIF4ENIF1 2610509L04Rik, 4E-T, Clast4, FLJ21601 ENSG00000184708 Eukaryotic translation initiation factor 4E nuclear import factor 1 22 31436977-31496108 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001619, HPA002078 Supported Validated Vesicles Expressed in all testis: 64.8 -LRRC26 bA350O14.10 ENSG00000184709 Leucine rich repeat containing 26 9 137168758-137170051 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056312 Approved Supported Plasma membrane Group enriched 6 colon: 10.5;prostate: 29.3;salivary gland: 26.7 small intestine: 3.6 -SERINC4 FLJ40363 ENSG00000184716 Serine incorporator 4 15 43794162-43800221 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018526 Uncertain Tissue enriched 10 testis: 2.2 endometrium: 0.2 -RNLS C10orf59, FLJ11218, renalase ENSG00000184719 Renalase, FAD-dependent amine oxidase 10 88273864-88584530 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all kidney: 26.6 -KRTAP6-1 C21orf103, KAP6.1 ENSG00000184724 Keratin associated protein 6-1 21 30613431-30613930 Predicted intracellular proteins No evidence No evidence No evidence Not detected testis: 0.1 -APOBR APOB100R, APOB48R ENSG00000184730 Apolipoprotein B receptor 16 28494649-28498970 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041667, HPA042093 Supported Tissue enhanced 0 spleen: 31.3 appendix: 28.3 -FAM110C ENSG00000184731 Family with sequence similarity 110, member C 2 38814-46870 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036144, HPA036145 Uncertain Mixed seminal vesicle: 28.8 -DDX53 CAGE, CT26 ENSG00000184735 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 X 22999961-23003589 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 15 testis: 9.9 epididymis: 0.6 -ATL3 DKFZP564J0863 ENSG00000184743 Atlastin GTPase 3 11 63624087-63671921 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065702 Supported Endoplasmic reticulum Expressed in all testis: 66.0 -NDUFA12 B17.2, DAP13 ENSG00000184752 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 12 94897055-95003770 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039903 Supported Supported Mitochondria Expressed in all heart muscle: 190.0 -AC013269.5 ENSG00000184761 2 130539095-130549883 Predicted intracellular proteins No evidence No evidence Not detected epididymis: 0.0 -SMIM10 CXorf69 ENSG00000184785 Small integral membrane protein 10 X 134990938-134992473 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 parathyroid gland: 63.1 testis: 50.5 -TCTE3 TCTEX1D3 ENSG00000184786 T-complex-associated-testis-expressed 3 6 169740114-169751587 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 109 testis: 17.2 epididymis: 0.1 -UBE2G2 UBC7 ENSG00000184787 Ubiquitin-conjugating enzyme E2G 2 21 44768580-44802019 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003332 Approved Expressed in all seminal vesicle: 26.2 -SATL1 ENSG00000184788 Spermidine/spermine N1-acetyl transferase-like 1 X 85092287-85109048 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060369 Uncertain Tissue enhanced 0 testis: 1.3 cerebral cortex: 0.4 -OSBP2 KIAA1664, ORP-4, ORP4, OSBPL1 ENSG00000184792 Oxysterol binding protein 2 22 30693782-30907824 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021514 Uncertain Approved Cytosol Tissue enhanced 0 testis: 34.7 bone marrow: 31.9 -TUSC5 IFITMD3, LOST1 ENSG00000184811 Tumor suppressor candidate 5 17 1279663-1300987 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA050825 Approved Tissue enriched 18 adipose tissue: 109.9 breast: 6.0 -PRR23B FLJ46116 ENSG00000184814 Proline rich 23B 3 139019031-139020926 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047473 Uncertain Tissue enriched 16 testis: 1.5 epididymis: 0.0 -ZBTB7C ZBTB36, ZNF857C ENSG00000184828 Zinc finger and BTB domain containing 7C 18 48026673-48410752 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014433 Uncertain Mixed esophagus: 31.9 -APOO FAM121B, MGC4825, Mic23, MIC26, My025 ENSG00000184831 Apolipoprotein O X 23833353-23907934 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003187 Supported Approved Mitochondria
Cytosol Expressed in all cerebral cortex: 50.9 -PRR16 DSC54 ENSG00000184838 Proline rich 16 5 120464278-120687332 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049254 Approved Approved Nucleus
Midbody
Cytosol Mixed cervix: 21.6 -TMED9 HSGP25L2G, p24a2, p24alpha2 ENSG00000184840 Transmembrane p24 trafficking protein 9 5 177592158-177596124 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014650 Approved Expressed in all placenta: 211.2 -DRD1 ENSG00000184845 Dopamine receptor D1 5 175440039-175444208 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA013393 Uncertain Tissue enhanced 0 cerebral cortex: 8.0 prostate: 1.6 -TMEM186 C16orf51, DKFZP564K2062 ENSG00000184857 Transmembrane protein 186 16 8780384-8797648 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA018226, HPA063559 Uncertain Approved Cell Junctions Expressed in all parathyroid gland: 22.5 -SDR42E1 HSPC105 ENSG00000184860 Short chain dehydrogenase/reductase family 42E, member 1 16 81988855-82011488 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014388 Uncertain Mixed skin: 10.7 -RBM33 DKFZp434D1319, DKFZp686F102, MGC20460, PRR8 ENSG00000184863 RNA binding motif protein 33 7 155644451-155781485 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019232, HPA021497, HPA021768 Approved Approved Nucleoplasm Expressed in all bone marrow: 40.8 -ARMCX2 ALEX2, GASP9, KIAA0512 ENSG00000184867 Armadillo repeat containing, X-linked 2 X 101655281-101659891 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA005761 Supported Approved Nucleus
Mitochondria Tissue enhanced 0 epididymis: 199.2 thyroid gland: 107.0 -OR51B2 OR51B1P ENSG00000184881 Olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene) 11 5323359-5324297 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -BTBD6 BDPL ENSG00000184887 BTB (POZ) domain containing 6 14 105248490-105251093 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA031355 Approved Approved Nucleoplasm Expressed in all testis: 73.3 -SRY TDF ENSG00000184895 Sex determining region Y Y 2786855-2787699 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 1.0;testis: 2.8 esophagus: 0.7 -H1FX H1X, MGC15959, MGC8350 ENSG00000184897 H1 histone family, member X 3 129314771-129316277 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012235, HPA040099 Supported Validated Nucleus
Nucleoli Tissue enriched 7 bone marrow: 671.4 spleen: 98.1 -RBM43 C2orf38, FLJ45645 ENSG00000184898 RNA binding motif protein 43 2 151247940-151261879 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038204 Uncertain Approved Nucleus
Nucleoli Mixed thyroid gland: 20.5 -SUMO3 SMT3A, SMT3H1 ENSG00000184900 Small ubiquitin-like modifier 3 21 44805617-44818779 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012180, HPA042123, HPA048064 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all cerebral cortex: 81.1 -IMMP2L IMMP2L-IT1, IMP2 ENSG00000184903 Inner mitochondrial membrane peptidase subunit 2 7 110663051-111562517 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026711 Approved Approved Mitochondria Expressed in all thyroid gland: 39.4 -TCEAL2 my048, MY0876G05, WEX1 ENSG00000184905 Transcription elongation factor A (SII)-like 2 X 102125688-102127711 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA076317 Approved Nuclear speckles
Cytosol Tissue enhanced 0 cerebral cortex: 192.2 ovary: 77.9 -CLCNKB hClC-Kb ENSG00000184908 Chloride channel, voltage-sensitive Kb 1 16043736-16057308 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057717 Approved Tissue enhanced 0 kidney: 107.5 salivary gland: 22.1 -DMRTC1B ENSG00000184911 DMRT-like family C1B X 72777009-72848802 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046874, HPA046992 Uncertain Tissue enhanced 0 cerebral cortex: 16.7 ovary: 10.3 -JAG2 ENSG00000184916 Jagged 2 14 105140981-105168824 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025481, HPA030636, HPA050567 Approved Supported Vesicles Tissue enhanced 0 skin: 22.6 adipose tissue: 6.5 -FMNL1 C17orf1, C17orf1B, FMNL ENSG00000184922 Formin-like 1 17 45221444-45247320 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008129, HPA028288 Supported Approved Cytosol Expressed in all bone marrow: 175.4 -NUTM2A FAM22A ENSG00000184923 NUT family member 2A 10 87225448-87236908 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA064635 Uncertain Nuclear bodies Mixed skin: 1.9 -PTRHD1 C2orf79, LOC391356 ENSG00000184924 Peptidyl-tRNA hydrolase domain containing 1 2 24789734-24793382 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019951 Approved Approved Nucleoplasm Expressed in all adrenal gland: 14.1 -LCN12 MGC48935 ENSG00000184925 Lipocalin 12 9 136949551-136955497 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 30 epididymis: 44.4 thyroid gland: 1.4 -OR6A2 OR11-55, OR6A1, OR6A2P ENSG00000184933 Olfactory receptor, family 6, subfamily A, member 2 11 6794627-6795783 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -WT1 AWT1, GUD, WAGR, WIT-2 ENSG00000184937 Wilms tumor 1 11 32387775-32435630 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000327, HPA035717, HPA053848 Supported Supported Nucleoplasm Tissue enhanced 0 endometrium: 112.0;fallopian tube: 123.1;smooth muscle: 78.9 testis: 53.8 -ZFP90 KIAA1954, NK10, ZNF756 ENSG00000184939 ZFP90 zinc finger protein 16 68530090-68576072 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA029017 Uncertain Supported Vesicles
Plasma membrane
Centrosome Mixed parathyroid gland: 31.1 -AQP12A AQP12 ENSG00000184945 Aquaporin 12A 2 240691845-240698483 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA042216 Supported Tissue enriched 67 pancreas: 27.7 small intestine: 0.4 -FAM227A ENSG00000184949 Family with sequence similarity 227, member A 22 38578120-38656629 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003077 Uncertain Uncertain Nucleoplasm Tissue enhanced 0 fallopian tube: 3.7 testis: 3.5 -OR6C70 ENSG00000184954 Olfactory receptor, family 6, subfamily C, member 70 12 55469200-55470138 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Not detected epididymis: 0.0 -MUC6 ENSG00000184956 Mucin 6, oligomeric mucus/gel-forming 11 1012821-1036706 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002165 Supported Group enriched 31 duodenum: 26.7;seminal vesicle: 71.3;stomach: 37.8 epididymis: 1.4 -NOC4L MGC3162, NET49, UTP19 ENSG00000184967 Nucleolar complex associated 4 homolog 12 132144448-132152473 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053424 Supported Nucleus
Nucleoli Expressed in all testis: 24.8 -USP18 ENSG00000184979 Ubiquitin specific peptidase 18 22 18149899-18177397 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044768 Uncertain Approved Cytosol Mixed testis: 15.6 -NDUFA6 B14, CI-B14, LYRM6, NADHB14 ENSG00000184983 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 22 42085525-42090955 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 39.5 -CHRM5 ENSG00000184984 Cholinergic receptor, muscarinic 5 15 33968720-34067457 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA013172 Uncertain Tissue enhanced 0 cerebral cortex: 3.1;testis: 4.1 placenta: 2.5 -SORCS2 KIAA1329 ENSG00000184985 Sortilin-related VPS10 domain containing receptor 2 4 7192538-7742836 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061916 Approved Nucleus
Cytosol Tissue enhanced 0 cerebral cortex: 19.4 cervix: 10.4 -TMEM121 hole, MGC4659 ENSG00000184986 Transmembrane protein 121 14 105526603-105530202 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049857 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 4.8 spleen: 2.4 -TMEM106A MGC20235 ENSG00000184988 Transmembrane protein 106A 17 43211835-43220041 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed kidney: 23.1 -SIVA1 CD27BP, SIVA, Siva-1, Siva-2 ENSG00000184990 SIVA1, apoptosis-inducing factor 14 104753100-104768494 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065398, HPA066693 Supported Nucleoplasm Expressed in all bone marrow: 62.2 -BRI3BP BNAS1, HCCR-2, KG19 ENSG00000184992 BRI3 binding protein 12 124993700-125031231 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014957 Approved Approved Nucleoplasm
Mitochondria Mixed duodenum: 21.1 -IFNE IFNE1 ENSG00000184995 Interferon, epsilon 9 21480839-21482313 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 1.0 urinary bladder: 0.9 -SLC22A10 hOAT5, OAT5 ENSG00000184999 Solute carrier family 22, member 10 11 63137867-63369718 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 108 liver: 36.1 epididymis: 0.3 -DGAT1 ARGP1, DGAT ENSG00000185000 Diacylglycerol O-acyltransferase 1 8 144314584-144326910 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032853 Supported Approved Nucleoli
Endoplasmic reticulum Tissue enhanced 0 duodenum: 73.2;small intestine: 76.7 adipose tissue: 20.0 -RFX6 dJ955L16.1, MGC33442, RFXDC1 ENSG00000185002 Regulatory factor X, 6 6 116877212-116932163 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA037696, HPA037697 Approved Supported Nucleus
Nucleoli Tissue enhanced 0 adrenal gland: 6.0;stomach: 7.3 duodenum: 2.3 -ROBO2 KIAA1568 ENSG00000185008 Roundabout guidance receptor 2 3 75906695-77649964 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013371 Approved Approved Nucleus
Microtubule organizing center Tissue enhanced 0 cerebral cortex: 33.9 lung: 15.2 -AP3M1 ENSG00000185009 Adaptor-related protein complex 3, mu 1 subunit 10 74120255-74151063 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045591, HPA048380 Uncertain Expressed in all placenta: 45.6 -F8 DXS1253E, F8C, FVIII, HEMA ENSG00000185010 Coagulation factor VIII, procoagulant component X 154835788-155026940 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018777 Supported Expressed in all lung: 23.4 -NT5C1B AIRP, CN-IB ENSG00000185013 5'-nucleotidase, cytosolic IB 2 18562872-18589572 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056683 Uncertain Tissue enriched 16 testis: 57.8 parathyroid gland: 3.5 -CA13 CAXIII, FLJ37995, MGC59868 ENSG00000185015 Carbonic anhydrase XIII 8 85220587-85284073 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024689, CAB025567 Approved Uncertain Nucleus
Nucleoli
Vesicles Mixed small intestine: 16.9 -UBOX5 KIAA0860, RNF37, Ubce7ip5, UIP5 ENSG00000185019 U-box domain containing 5 20 3107573-3160196 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028871 Approved Approved Nucleoplasm Expressed in all fallopian tube: 7.1 -MAFF hMafF ENSG00000185022 V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 22 38200767-38216511 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025341, HPA055371 Approved Approved Nucleus
Mitochondria Mixed gallbladder: 66.4 -BRF1 BRF, GTF3B, hBRF, TAF3B2, TAF3C, TFIIIB90 ENSG00000185024 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 14 105209286-105315589 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051918 Approved Nucleoplasm
Nuclear bodies Expressed in all cerebral cortex: 21.7 -LRRC14B ENSG00000185028 Leucine rich repeat containing 14B 5 191511-195353 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA038046, HPA038047 Uncertain Group enriched 32 heart muscle: 14.8;skeletal muscle: 30.1 prostate: 0.7 -SEMA4B KIAA1745, MGC131831, SEMAC, SemC ENSG00000185033 Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 15 90160604-90229679 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA013372 Approved Expressed in all esophagus: 49.5 -MROH2A HEATR7B1 ENSG00000185038 Maestro heat-like repeat family member 2A 2 233775679-233833423 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA052107 Uncertain Uncertain Cytosol Group enriched 9 testis: 3.2;thyroid gland: 2.7 liver: 0.3 -SPDYE16 ENSG00000185040 Speedy/RINGO cell cycle regulator family member E16 7 76531319-76541459 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA044799, HPA051750 Uncertain Not detected testis: 0.9 -CIB1 CALMYRIN, CIB, KIP, SIP2-28 ENSG00000185043 Calcium and integrin binding 1 (calmyrin) 15 90229975-90234047 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012991, HPA048825 Approved Supported Nucleoplasm
Plasma membrane Expressed in all fallopian tube: 204.7 -ANKS1B AIDA-1, ANKS2, cajalin-2, EB-1 ENSG00000185046 Ankyrin repeat and sterile alpha motif domain containing 1B 12 98726457-99984654 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044628 Approved Vesicles
Plasma membrane
Cytosol Tissue enriched 8 cerebral cortex: 112.3 testis: 14.0 -NELFA NELF-A, WHSC2 ENSG00000185049 Negative elongation factor complex member A 4 1982714-2041903 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009960, HPA039858, HPA043931 Supported Validated Nucleoplasm
Nuclear bodies
Cytosol Expressed in all testis: 31.9 -SLC24A3 ENSG00000185052 Solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 20 19212646-19722937 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043400, HPA045497 Uncertain Mixed endometrium: 47.4 -SGCZ ZSG1 ENSG00000185053 Sarcoglycan, zeta 8 14089864-15238339 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA017585 Uncertain Tissue enhanced 0 cerebral cortex: 1.3;ovary: 3.4 breast: 0.7 -EFCAB10 ENSG00000185055 EF-hand calcium binding domain 10 7 105565120-105600875 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA019751 Uncertain Group enriched 9 fallopian tube: 43.3;testis: 39.8 lung: 4.6 -C5orf47 LOC133491 ENSG00000185056 Chromosome 5 open reading frame 47 5 173973779-174006140 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 253 testis: 39.1 cerebral cortex: 0.1 -KRT76 HUMCYT2A, KRT2B, KRT2P ENSG00000185069 Keratin 76, type II 12 52768155-52777345 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019656, HPA019696 Approved Tissue enriched 23 tonsil: 2.2 adipose tissue: 0.0 -FLRT2 ENSG00000185070 Fibronectin leucine rich transmembrane protein 2 14 85530144-85654426 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 ovary: 36.4 cervix: 16.6 -INTS5 INT5, KIAA1698 ENSG00000185085 Integrator complex subunit 5 11 62646848-62653302 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056915 Uncertain Supported Nucleus Expressed in all fallopian tube: 21.1 -FAM169B FLJ39743, KIAA0888L ENSG00000185087 Family with sequence similarity 169, member B 15 98437162-98514382 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055979 Uncertain Mixed testis: 1.5 -RPS27L ENSG00000185088 Ribosomal protein S27-like 15 63125872-63158021 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066851 Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all adrenal gland: 223.3 -MANEAL FLJ31434 ENSG00000185090 Mannosidase, endo-alpha-like 1 37793802-37801137 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA063423 Approved Golgi apparatus Tissue enhanced 0 cerebral cortex: 27.2 adrenal gland: 9.6 -ADSSL1 FLJ38602 ENSG00000185100 Adenylosuccinate synthase like 1 14 104724186-104747325 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 skeletal muscle: 428.0 heart muscle: 64.7 -ANO9 PIG5, TMEM16J, TP53I5 ENSG00000185101 Anoctamin 9 11 417933-442011 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039948, HPA040112 Approved Uncertain Golgi apparatus Tissue enhanced 0 duodenum: 32.4;small intestine: 31.6 skin: 21.6 -FAF1 CGI-03, hFAF1, HFAF1s, UBXD12, UBXN3A ENSG00000185104 Fas (TNFRSF6) associated factor 1 1 50437028-50960263 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018253, CAB072814 Approved Validated Nucleus Expressed in all testis: 59.1 -MYADML2 LOC255275 ENSG00000185105 Myeloid-associated differentiation marker-like 2 17 81939645-81947233 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041856, HPA048476 Uncertain Tissue enriched 20 skeletal muscle: 30.9 heart muscle: 1.5 -FAM43A FLJ90022 ENSG00000185112 Family with sequence similarity 43, member A 3 194686544-194689037 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA048345 Uncertain Approved Vesicles Tissue enhanced 0 spleen: 34.6 placenta: 18.2 -NDNL2 HCA4, MAGEG1, MAGEL3, NSE3, NSMCE3 ENSG00000185115 Necdin-like 2, SMC5-SMC6 complex component 15 29268149-29269829 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all testis: 18.8 -HSF1 HSTF1 ENSG00000185122 Heat shock transcription factor 1 8 144291591-144314722 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004239, HPA008888 Supported Supported Nucleoplasm
Cytosol Expressed in all testis: 127.1 -C6orf120 bA160E12.4 ENSG00000185127 Chromosome 6 open reading frame 120 6 169702190-169704856 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039626 Uncertain Expressed in all placenta: 28.7 -PURA PUR-ALPHA, PUR1, PURALPHA ENSG00000185129 Purine-rich element binding protein A 5 140107777-140125619 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed parathyroid gland: 26.4 -HIST1H2BL dJ97D16.4, H2B/c, H2BFC ENSG00000185130 Histone cluster 1, H2bl 6 27807444-27807931 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Tissue enriched 6 bone marrow: 3.7 lymph node: 0.6 -INPP5J INPP5, PIB5PA ENSG00000185133 Inositol polyphosphate-5-phosphatase J 22 31122731-31134696 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034539 Approved Nucleoli
Cytosol Group enriched 10 parathyroid gland: 211.5;thyroid gland: 241.2 small intestine: 22.8 -NPY2R ENSG00000185149 Neuropeptide Y receptor Y2 4 155208629-155217078 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 breast: 1.0;cerebral cortex: 1.7;testis: 1.0 rectum: 0.6 -MIXL1 MILD1, MIXL ENSG00000185155 Mix paired-like homeobox 1 226223618-226227054 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA005662 Approved Nucleus Tissue enhanced 0 tonsil: 3.2 lymph node: 2.8 -MFSD6L FLJ35773 ENSG00000185156 Major facilitator superfamily domain containing 6-like 17 8797162-8799349 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023164 Uncertain Tissue enhanced 0 testis: 29.7 parathyroid gland: 8.3 -LRRC37B ENSG00000185158 Leucine rich repeat containing 37B 17 32007872-32053504 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015134, HPA015135 Approved Approved Cytosol Tissue enhanced 0 testis: 32.4 bone marrow: 16.5 -DDX51 ENSG00000185163 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 12 132136594-132144335 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039503 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all cerebral cortex: 11.4 -NOMO2 NOMO, PM5 ENSG00000185164 NODAL modulator 2 16 18417325-18562211 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046697, HPA061174 Approved Expressed in all parathyroid gland: 154.9 -AQP12B INSSA3 ENSG00000185176 Aquaporin 12B 2 240676418-240682906 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042216 Supported Tissue enriched 56 pancreas: 35.7 duodenum: 0.6 -ZNF479 KR19 ENSG00000185177 Zinc finger protein 479 7 57119614-57139864 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 42 testis: 4.2 adipose tissue: 0.0 -SIGIRR TIR8 ENSG00000185187 Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 11 405716-417455 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023188 Approved Approved Nucleoli fibrillar center
Cytosol Expressed in all spleen: 65.9 -NRBP2 DKFZp434P086 ENSG00000185189 Nuclear receptor binding protein 2 8 143833594-143840974 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB020944, HPA029051, HPA029052 Approved Approved Cytosol Expressed in all cerebral cortex: 55.4 -PRSS57 PRSSL1, UNQ782 ENSG00000185198 Protease, serine, 57 19 685546-695498 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 170 bone marrow: 103.6 spleen: 0.6 -IFITM2 1-8D ENSG00000185201 Interferon induced transmembrane protein 2 11 307631-315272 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004337 Uncertain Expressed in all appendix: 722.4 -TNFAIP2 B94, EXOC3L3 ENSG00000185215 Tumor necrosis factor, alpha-induced protein 2 14 103123442-103137439 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB004598, HPA030624 Supported Approved Nucleus
Nuclear membrane
Golgi apparatus
Cytosol Expressed in all urinary bladder: 211.4 -ZNF445 ZKSCAN15, ZNF168, ZSCAN47 ENSG00000185219 Zinc finger protein 445 3 44431720-44477670 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006678 Uncertain Approved Nucleus
Mitochondria
Cytosol Mixed parathyroid gland: 7.1 -PGBD2 ENSG00000185220 PiggyBac transposable element derived 2 1 248906196-248919946 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA029888, HPA029889, HPA029890 Uncertain Supported Vesicles Mixed thyroid gland: 13.5 -WBP5 DKFZp313K1940, TCEAL9, WEX6 ENSG00000185222 WW domain binding protein 5 X 103356445-103358469 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA011790 Uncertain Approved Nucleoplasm
Cytosol Expressed in all placenta: 274.5 -MC2R ACTHR ENSG00000185231 Melanocortin 2 receptor (adrenocorticotropic hormone) 18 13882044-13915707 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 24 adrenal gland: 50.8 epididymis: 2.1 -RAB11B H-YPT3 ENSG00000185236 RAB11B, member RAS oncogene family 19 8389981-8404434 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054396 Approved Vesicles
Microtubule organizing center Expressed in all thyroid gland: 152.7 -PRMT3 HRMT1L3 ENSG00000185238 Protein arginine methyltransferase 3 11 20387530-20509294 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007832, CAB022083 Uncertain Expressed in all thyroid gland: 27.4 -GP1BA CD42b, GP1B ENSG00000185245 Glycoprotein Ib (platelet), alpha polypeptide 17 4932297-4935030 CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002496, HPA013316 Supported Tissue enhanced 0 lymph node: 17.5 tonsil: 7.9 -PRPF39 FLJ11128, FLJ20666 ENSG00000185246 Pre-mRNA processing factor 39 14 45084099-45116282 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001176 Approved Approved Nucleoplasm Mixed prostate: 9.8 -MAGEA11 CT1.11, MAGE-11, MAGE11, MAGEA-11, MGC10511 ENSG00000185247 Melanoma antigen family A11 X 149688228-149717266 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA052687 Supported Nucleoplasm
Nuclear bodies
Cytosol Group enriched 15 epididymis: 25.3;testis: 6.8 placenta: 1.0 -PPIL6 bA425D10.6, dJ919F19.1, MGC41939, RSPH12 ENSG00000185250 Peptidylprolyl isomerase (cyclophilin)-like 6 6 109390215-109441171 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036717 Approved Approved Nucleus
Golgi apparatus
Cytosol Tissue enhanced 0 fallopian tube: 52.8;testis: 32.6 thyroid gland: 17.6 -ZNF74 Cos52, Zfp520, ZNF520 ENSG00000185252 Zinc finger protein 74 22 20394115-20408461 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA003354 Approved Supported Nucleoplasm
Actin filaments Mixed ovary: 4.9 -KIAA0825 C5orf36, DKFZp686F0372, MGC34713 ENSG00000185261 KIAA0825 5 94152966-94618604 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038030, HPA038031 Uncertain Mixed testis: 5.5 -UBALD2 FAM100B, MGC29814 ENSG00000185262 UBA-like domain containing 2 17 76265202-76271299 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023046 Uncertain Expressed in all bone marrow: 141.0 -TEX33 C22orf33, EAN57, MGC35206 ENSG00000185264 Testis expressed 33 22 36991120-37007841 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA005998 Supported Tissue enriched 569 testis: 86.6 cerebral cortex: 0.1 -CDNF ARMETL1 ENSG00000185267 Cerebral dopamine neurotrophic factor 10 14819250-14838575 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044587 Uncertain Tissue enhanced 0 testis: 20.1 skeletal muscle: 12.5 -NOTUM ENSG00000185269 Notum pectinacetylesterase homolog (Drosophila) 17 81952507-81961840 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 56 placenta: 191.3 liver: 3.4 -KLHL33 ENSG00000185271 Kelch-like family member 33 14 20428811-20435642 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA056560 Uncertain Tissue enriched 10 skeletal muscle: 29.3 endometrium: 2.8 -RBM11 ENSG00000185272 RNA binding motif protein 11 21 14216130-14228372 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045885 Supported Nucleoplasm Tissue enriched 17 epididymis: 55.6 cerebral cortex: 3.2 -WBSCR17 GalNAc-T5L, GALNTL3 ENSG00000185274 Williams-Beuren syndrome chromosome region 17 7 71132169-71713600 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA013624, HPA047986 Approved Uncertain Nucleus
Nucleoli
Nuclear bodies
Golgi apparatus Tissue enhanced 0 cerebral cortex: 76.7 ovary: 28.9 -ZBTB37 MGC2629, ZNF908 ENSG00000185278 Zinc finger and BTB domain containing 37 1 173868082-173903549 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA023438 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Tissue enhanced 0 testis: 17.3 spleen: 5.5 -NUPR1L ENSG00000185290 Nuclear protein, transcriptional regulator, 1-like 7 56114681-56116400 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 13 testis: 112.3 thyroid gland: 8.7 -IL3RA CD123 ENSG00000185291 Interleukin 3 receptor, alpha (low affinity) X 1336616-1382689 CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003539, CAB018374 Approved Expressed in all lung: 33.8 -SPPL2C IMP5 ENSG00000185294 Signal peptide peptidase like 2C 17 45844835-45847072 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 21 testis: 2.1 adipose tissue: 0.0 -CCDC137 MGC16597 ENSG00000185298 Coiled-coil domain containing 137 17 81666364-81673904 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052637, HPA053914 Uncertain Validated Nucleoli Expressed in all skin: 19.7 -SFTPA2 COLEC5, SP-A2 ENSG00000185303 Surfactant protein A2 10 79555852-79560397 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB002439, HPA042638, HPA045752, HPA049368 Supported Tissue enriched 446 lung: 15999.4 prostate: 35.9 -RGPD2 RANBP2L2, RGP2 ENSG00000185304 RANBP2-like and GRIP domain containing 2 2 87755955-87825952 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049497, HPA051675, HPA067564 Uncertain Approved Nuclear membrane
Vesicles Tissue enhanced 0 testis: 13.1 placenta: 8.3 -ARL15 ARFRP2, FLJ20051 ENSG00000185305 ADP-ribosylation factor-like 15 5 53883945-54310582 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044604, HPA063820 Uncertain Approved Golgi apparatus
Plasma membrane
Cell Junctions Expressed in all placenta: 44.4 -C12orf56 ENSG00000185306 Chromosome 12 open reading frame 56 12 64264762-64391192 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA056986 Supported Tissue enriched 21 testis: 15.2 skin: 0.7 -SCN10A hPN3, Nav1.8, PN3, SNS ENSG00000185313 Sodium channel, voltage gated, type X alpha subunit 3 38696802-38794010 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.3 -CDK10 PISSLRE ENSG00000185324 Cyclin-dependent kinase 10 16 89680737-89696364 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059634, HPA067060 Supported Nucleoplasm
Midbody
Midbody ring Expressed in all thyroid gland: 31.4 -TMEM105 FLJ38792 ENSG00000185332 Transmembrane protein 105 17 81311270-81330674 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed thyroid gland: 1.0 -SOCS1 Cish1, JAB, SOCS-1, SSI-1, TIP3 ENSG00000185338 Suppressor of cytokine signaling 1 16 11254405-11256179 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB010355, HPA074108 Approved Supported Nucleoplasm
Cytoplasmic bodies Tissue enhanced 0 appendix: 20.0 lymph node: 15.9 -TCN2 D22S676, D22S750, TC2 ENSG00000185339 Transcobalamin II 22 30606838-30627278 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000837 Approved Cytosol Expressed in all kidney: 121.6 -GAS2L1 GAR22 ENSG00000185340 Growth arrest-specific 2 like 1 22 29306582-29312785 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019858 Approved Approved Plasma membrane
Cell Junctions Expressed in all testis: 32.2 -ATP6V0A2 a2, ATP6a2, ATP6N1D, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1 ENSG00000185344 ATPase, H+ transporting, lysosomal V0 subunit a2 12 123712318-123761755 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044279 Approved Approved Plasma membrane
Cytosol Expressed in all skin: 15.2 -PARK2 AR-JP, parkin, PDJ ENSG00000185345 Parkin RBR E3 ubiquitin protein ligase 6 161347420-162727771 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB016257 Approved Mixed cerebral cortex: 13.8 -C14orf80 ENSG00000185347 Chromosome 14 open reading frame 80 14 105489855-105499575 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039049, HPA039050 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Mixed appendix: 6.8 -HS6ST3 ENSG00000185352 Heparan sulfate 6-O-sulfotransferase 3 13 96090839-96839562 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051513 Approved Nucleus
Nucleoli fibrillar center Tissue enhanced 0 cerebral cortex: 27.8 urinary bladder: 6.2 -HGS Hrs, Vps27, ZFYVE8 ENSG00000185359 Hepatocyte growth factor-regulated tyrosine kinase substrate 17 81683326-81703138 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004872, HPA007728 Uncertain Validated Endosomes
Lysosomes
Cytosol Expressed in all skin: 85.0 -TNFAIP8L1 MGC17791 ENSG00000185361 Tumor necrosis factor, alpha-induced protein 8-like 1 19 4639518-4655568 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 fallopian tube: 36.9 spleen: 17.9 -OR2V1 OR2V1P, OST265 ENSG00000185372 Olfactory receptor, family 2, subfamily V, member 1 5 181124357-181125304 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA049953 Uncertain Tissue enriched 24 fallopian tube: 2.5 testis: 0.1 -RAD51D HsTRAD, R51H3, RAD51L3, Trad ENSG00000185379 RAD51 paralog D 17 35092208-35121522 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed cerebral cortex: 9.6 -OR7A17 HTPCRX19 ENSG00000185385 Olfactory receptor, family 7, subfamily A, member 17 19 14880426-14881452 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.8 -MAPK11 p38-2, p38Beta, PRKM11, SAPK2 ENSG00000185386 Mitogen-activated protein kinase 11 22 50263713-50270767 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012961, HPA045069 Approved Approved Mitochondria Mixed cerebral cortex: 27.8 -SP140L ENSG00000185404 SP140 nuclear body protein-like 2 230327184-230403732 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055864 Uncertain Approved Nucleoplasm Mixed spleen: 29.2 -MRPL30 MRP-L28, RPML28 ENSG00000185414 Mitochondrial ribosomal protein L30 2 99181079-99197626 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047255 Approved Expressed in all thyroid gland: 20.3 -TARSL2 FLJ25005 ENSG00000185418 Threonyl-tRNA synthetase-like 2 15 101653598-101724604 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063963, HPA066697 Uncertain Approved Cytosol Expressed in all cerebral cortex: 15.7 -SMYD3 KMT3E, ZMYND1, ZNFN3A1 ENSG00000185420 SET and MYND domain containing 3 1 245749342-246507312 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB012229, HPA045821, HPA054352 Approved Approved Golgi apparatus
Vesicles Expressed in all thyroid gland: 26.9 -METTL7A DKFZP586A0522 ENSG00000185432 Methyltransferase like 7A 12 50923472-50932517 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017434 Supported Lipid droplets Expressed in all thyroid gland: 402.1 -IFNLR1 CRF2/12, IFNLR, IL-28R1, IL28RA ENSG00000185436 Interferon, lambda receptor 1 1 24154157-24187959 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA017319 Uncertain Approved Cytosol Mixed small intestine: 10.3 -SH3BGR 21-GARP ENSG00000185437 SH3 domain binding glutamate-rich protein 21 39445855-39515506 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB003685, HPA030690 Supported Approved Plasma membrane
Cytosol Group enriched 7 heart muscle: 89.7;skeletal muscle: 436.1 prostate: 40.2 -FAM174B LOC400451, MGC102891 ENSG00000185442 Family with sequence similarity 174, member B 15 92617443-92809884 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015306 Approved Approved Intermediate filaments Mixed thyroid gland: 61.6 -FAM47A MGC27003 ENSG00000185448 Family with sequence similarity 47, member A X 34129756-34132314 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA000610 Uncertain Tissue enriched 55 testis: 5.5 epididymis: 0.0 -C19orf68 LOC374920 ENSG00000185453 Chromosome 19 open reading frame 68 19 48170692-48197620 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061028 Uncertain Approved Nucleus Mixed cerebral cortex: 7.8 -KPNA7 ENSG00000185467 Karyopherin alpha 7 (importin alpha 8) 7 99173574-99207506 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031395 Uncertain Group enriched 5 fallopian tube: 1.9;stomach: 6.4 gallbladder: 0.8 -TMEM179B ENSG00000185475 Transmembrane protein 179B 11 62787415-62790405 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016585, HPA062068 Validated Nuclear speckles Expressed in all epididymis: 86.2 -GPRIN3 FLJ42625, GRIN3 ENSG00000185477 GPRIN family member 3 4 89236386-89308010 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043148, HPA057666, HPA059092 Uncertain Approved Nucleus
Nucleoli Mixed appendix: 12.3 -KRT6B KRTL1 ENSG00000185479 Keratin 6B, type II 12 52446651-52452126 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000130, HPA045697, HPA061168 Supported Approved Intermediate filaments Tissue enriched 10 esophagus: 673.4 tonsil: 69.9 -PARPBP C12orf48, FLJ20641, PARI ENSG00000185480 PARP1 binding protein 12 102120185-102197520 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039677 Approved Supported Nucleoplasm Mixed testis: 7.2 -STAC3 MGC2793 ENSG00000185482 SH3 and cysteine rich domain 3 12 57243453-57251193 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039285, HPA039527 Validated Nucleoplasm
Cytosol Tissue enriched 24 skeletal muscle: 802.5 esophagus: 33.3 -ROR1 NTRKR1 ENSG00000185483 Receptor tyrosine kinase-like orphan receptor 1 1 63774022-64181498 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057016 Uncertain Microtubules
Cytokinetic bridge Tissue enhanced 0 parathyroid gland: 51.2 endometrium: 12.1 -MUC1 ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM ENSG00000185499 Mucin 1, cell surface associated 1 155185824-155192916 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000036, CAB001986, HPA004179, HPA007235, HPA008855 Supported Validated Vesicles
Plasma membrane Tissue enhanced 0 lung: 447.5;stomach: 650.2 cervix: 286.5 -FAAP100 C17orf70, FLJ22175 ENSG00000185504 Fanconi anemia core complex associated protein 100 17 81539885-81553961 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023954, HPA024626, HPA026532 Uncertain Validated Nucleoplasm
Intermediate filaments
Cytosol Expressed in all spleen: 22.8 -IRF7 ENSG00000185507 Interferon regulatory factor 7 11 612553-615999 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017694, HPA052757 Approved Uncertain Nucleoplasm
Cytosol Mixed bone marrow: 1.8 -L3MBTL1 dJ138B7.3, DKFZp586P1522, KIAA0681, L3MBTL, ZC2HC3 ENSG00000185513 L(3)mbt-like 1 (Drosophila) 20 43507680-43550950 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA056389 Supported Nucleus
Plasma membrane Mixed testis: 10.1 -BRCC3 BRCC36, C6.1A, CXorf53 ENSG00000185515 BRCA1/BRCA2-containing complex, subunit 3 X 155071420-155123074 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048737 Supported Nucleoplasm Expressed in all parathyroid gland: 20.8 -SV2B HsT19680, KIAA0735 ENSG00000185518 Synaptic vesicle glycoprotein 2B 15 91099950-91301309 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046247 Approved Tissue enriched 23 cerebral cortex: 48.1 adipose tissue: 2.1 -FAM131C C1orf117, FLJ36766 ENSG00000185519 Family with sequence similarity 131, member C 1 16057769-16073632 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA031046 Uncertain Approved Nucleoli
Intermediate filaments
Cytosol Tissue enhanced 0 adrenal gland: 3.3;cerebral cortex: 4.8;kidney: 3.8 heart muscle: 1.2 -LMNTD2 C11orf35, MGC35138 ENSG00000185522 Lamin tail domain containing 2 11 554855-560779 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058474, HPA073912 Uncertain Approved Cytoplasmic bodies Tissue enhanced 0 epididymis: 13.5 fallopian tube: 12.1 -SPATA45 C1orf227, LOC149643 ENSG00000185523 Spermatogenesis associated 45 1 212830141-212847649 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA049921 Uncertain Tissue enriched 11 testis: 13.1 fallopian tube: 1.2 -PDE6G PDEG, RP57 ENSG00000185527 Phosphodiesterase 6G, cGMP-specific, rod, gamma 17 81650459-81663112 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lymph node: 26.7;spleen: 34.0 placenta: 18.8 -PRKG1 PGK, PKG, PRKG1B, PRKGR1B ENSG00000185532 Protein kinase, cGMP-dependent, type I 10 50991358-52298350 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007699, CAB009629 Approved Approved Vesicles
Cytosol Mixed smooth muscle: 24.5 -NR2F2 ARP1, COUP-TFII, COUPTFB, NF-E3, SVP40, TFCOUP2 ENSG00000185551 Nuclear receptor subfamily 2, group F, member 2 15 96325938-96340263 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 ovary: 360.9 endometrium: 186.6 -DLK1 Delta1, FA1, pG2, Pref-1, ZOG ENSG00000185559 Delta-like 1 homolog (Drosophila) 14 100725705-100738224 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005872, HPA053879, HPA062262 Supported Approved Golgi apparatus Group enriched 20 adrenal gland: 1598.8;placenta: 2319.0 ovary: 99.9 -TLCD2 ENSG00000185561 TLC domain containing 2 17 1702790-1710438 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA046063 Uncertain Approved Nucleoli
Vesicles Mixed adipose tissue: 6.1 -LSAMP IGLON3, LAMP ENSG00000185565 Limbic system-associated membrane protein 3 115802363-117139389 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054051, HPA076122 Approved Cytosol Tissue enhanced 0 cerebral cortex: 103.1 prostate: 42.3 -AHNAK2 C14orf78 ENSG00000185567 AHNAK nucleoprotein 2 14 104937244-104978357 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000878, HPA002940, HPA004145, HPA020111 Supported Validated Plasma membrane
Cytosol Tissue enriched 8 skin: 346.3 smooth muscle: 45.9 -OLFML2A FLJ00237 ENSG00000185585 Olfactomedin-like 2A 9 124777158-124814885 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021180, HPA022254 Approved Approved Nucleoplasm
Cytosol Mixed spleen: 48.3 -SP1 ENSG00000185591 Sp1 transcription factor 12 53380176-53416446 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000330, HPA001853, HPA012292 Supported Validated Nucleoplasm Expressed in all endometrium: 53.9 -SPATA8 MGC44294 ENSG00000185594 Spermatogenesis associated 8 15 96783389-96785615 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 1465 testis: 402.0 placenta: 0.2 -MRPL40 MRP-L22, NLVCF ENSG00000185608 Mitochondrial ribosomal protein L40 22 19431902-19436075 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006181 Approved Validated Nucleoli
Mitochondria Expressed in all thyroid gland: 34.6 -DBX2 FLJ16139 ENSG00000185610 Developing brain homeobox 2 12 45014672-45051099 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA066053 Uncertain Group enriched 5 cerebral cortex: 4.1;testis: 1.2 skin: 0.5 -FAM212A C3orf54 ENSG00000185614 Family with sequence similarity 212, member A 3 49803254-49805030 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041879 Uncertain Approved Nucleoplasm
Vesicles Tissue enhanced 0 skin: 24.5 lung: 7.0 -PDIA2 PDA2, PDI, PDIP, PDIR ENSG00000185615 Protein disulfide isomerase family A, member 2 16 283152-287215 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051692, HPA053492 Supported Approved Nucleoplasm
Cytosol Tissue enriched 7 pancreas: 523.4 stomach: 71.3 -PCGF3 DONG1, FLJ36550, MGC40413, RNF3, RNF3A ENSG00000185619 Polycomb group ring finger 3 4 705748-770640 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061879 Supported Nucleoplasm Expressed in all skin: 79.4 -LMLN Gp63, Msp ENSG00000185621 Leishmanolysin-like (metallopeptidase M8 family) 3 197960200-198043720 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA016481, HPA028844 Uncertain Supported Focal adhesion sites
Cytosol Tissue enhanced 0 testis: 18.7 epididymis: 12.7 -P4HB DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB ENSG00000185624 Prolyl 4-hydroxylase, beta polypeptide 17 81843159-81860694 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012463, HPA018884 Supported Supported Endoplasmic reticulum Expressed in all small intestine: 515.3 -PSMD13 p40.5, Rpn9 ENSG00000185627 Proteasome 26S subunit, non-ATPase 13 11 236546-252984 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038691, HPA038692 Approved Approved Nuclear speckles
Cytosol Expressed in all thyroid gland: 41.6 -PBX1 ENSG00000185630 Pre-B-cell leukemia homeobox 1 1 164555584-164899296 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003505, HPA003881, CAB018768 Supported Validated Nucleoplasm Expressed in all endometrium: 246.5 -NDUFA4L2 FLJ26118, NUOMS ENSG00000185633 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 12 57234903-57240715 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA055323 Approved Mitochondria Tissue enhanced 0 esophagus: 152.9;skin: 191.9 placenta: 103.6 -SHC4 RaLP ENSG00000185634 SHC (Src homology 2 domain containing) family, member 4 15 48823735-48963444 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA074146 Approved Cytosol Group enriched 7 cerebral cortex: 13.2;testis: 20.4 gallbladder: 2.3 -KRT79 K6L, KRT6L ENSG00000185640 Keratin 79, type II 12 52821410-52834295 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059347 Supported Group enriched 9 breast: 4.0;skin: 17.2 esophagus: 1.1 -ZFP36L1 Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B ENSG00000185650 ZFP36 ring finger protein-like 1 14 68787660-68796253 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001301 Uncertain Expressed in all endometrium: 580.8 -UBE2L3 UBCH7 ENSG00000185651 Ubiquitin-conjugating enzyme E2L 3 22 21549447-21624034 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045609, HPA062415 Approved Supported Nucleus
Cytosol Expressed in all cerebral cortex: 67.4 -NTF3 NGF2 ENSG00000185652 Neurotrophin 3 12 5432112-5521536 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA032001 Approved Tissue enhanced 0 ovary: 13.5 spleen: 6.3 -BRWD1 C21orf107, DCAF19, FLJ11315, N143, WDR9 ENSG00000185658 Bromodomain and WD repeat domain containing 1 21 39184176-39321559 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030943, HPA030944, HPA030945, CAB034184 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all cerebral cortex: 77.9 -SMIM23 C5orf50, LOC644994 ENSG00000185662 Small integral membrane protein 23 5 171785872-171794598 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 37 testis: 40.0 epididymis: 1.0 -PMEL D12S53E, gp100, Pmel17, SI, SIL, SILV ENSG00000185664 Premelanosome protein 12 55954105-55973317 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031649 Supported Tissue enriched 12 skin: 133.7 breast: 10.8 -SYN3 ENSG00000185666 Synapsin III 22 32512552-33058372 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034566 Uncertain Tissue enhanced 0 cerebral cortex: 9.6;testis: 8.2 placenta: 5.0 -POU3F1 OCT6, OTF6, SCIP ENSG00000185668 POU class 3 homeobox 1 1 38043827-38046794 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055980, HPA073824 Validated Nucleoplasm Tissue enriched 18 skin: 38.6 cerebral cortex: 2.1 -SNAI3 SMUC, Zfp293, ZNF293 ENSG00000185669 Snail family zinc finger 3 16 88677682-88686493 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA016757, HPA071127 Uncertain Approved Nucleoplasm Tissue enhanced 0 skeletal muscle: 10.9 lymph node: 4.4 -ZBTB3 FLJ23392 ENSG00000185670 Zinc finger and BTB domain containing 3 11 62748319-62754188 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035321, HPA035322 Approved Approved Mitochondria Mixed skin: 7.0 -LYG2 LYGH ENSG00000185674 Lysozyme G-like 2 2 99242246-99255282 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039179 Uncertain Tissue enhanced 0 testis: 2.6 epididymis: 1.2 -MORN5 C9orf113, C9orf18, FLJ46909 ENSG00000185681 MORN repeat containing 5 9 122159908-122200088 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 6 fallopian tube: 174.0;testis: 105.8 smooth muscle: 24.5 -EP400NL FLJ33915 ENSG00000185684 EP400 N-terminal like 12 132084283-132131639 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA068417 Approved Tissue enriched 9 testis: 28.7 spleen: 3.2 -PRAME CT130, MAPE ENSG00000185686 Preferentially expressed antigen in melanoma 22 22547701-22559361 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045153 Supported Group enriched 8 epididymis: 16.4;testis: 80.4 endometrium: 6.3 -C6orf201 dJ1013A10.5 ENSG00000185689 Chromosome 6 open reading frame 201 6 4079209-4130951 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 23 testis: 29.9 fallopian tube: 1.2 -MYBL1 A-myb, AMYB ENSG00000185697 V-myb avian myeloblastosis viral oncogene homolog-like 1 8 66562175-66614247 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008791, CAB017780 Uncertain Approved Nucleus
Nucleoli
Cytosol Tissue enhanced 0 lymph node: 24.5;testis: 21.3 tonsil: 15.4 -C16orf52 ENSG00000185716 Chromosome 16 open reading frame 52 16 22007638-22087534 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all parathyroid gland: 39.5 -DRG1 NEDD3 ENSG00000185721 Developmentally regulated GTP binding protein 1 22 31399523-31528740 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001218 Approved Supported Nuclear bodies
Cytosol Expressed in all testis: 263.5 -ANKFY1 ANKHZN, BTBD23, KIAA1255, RANK-5, ZFYVE14 ENSG00000185722 Ankyrin repeat and FYVE domain containing 1 17 4163907-4263977 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024513, HPA024522, HPA065849 Approved Validated Endosomes Expressed in all parathyroid gland: 37.2 -YTHDF3 FLJ31657 ENSG00000185728 YTH N(6)-methyladenosine RNA binding protein 3 8 63168553-63212786 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048703 Approved Nuclear membrane
Nuclear speckles
Cytosol Expressed in all bone marrow: 59.2 -ZNF696 FLJ14129 ENSG00000185730 Zinc finger protein 696 8 143289676-143298061 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057855, HPA072473 Uncertain Approved Nucleus
Nucleoli Mixed cerebral cortex: 9.8 -ADARB2 ADAR3, hRED2, RED2 ENSG00000185736 Adenosine deaminase, RNA-specific, B2 (non-functional) 10 1177318-1737476 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031333 Uncertain Tissue enriched 6 cerebral cortex: 13.1 testis: 2.1 -NRG3 ENSG00000185737 Neuregulin 3 10 81875314-82987179 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 30.4 fallopian tube: 7.3 -SRL ENSG00000185739 Sarcalumenin 16 4189374-4242080 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041535, HPA045520 Supported Group enriched 16 heart muscle: 161.3;skeletal muscle: 178.9 esophagus: 10.3 -C11orf87 LOC399947, LOH11CR1A, NEURIM1 ENSG00000185742 Chromosome 11 open reading frame 87 11 109422120-109429114 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA034656 Approved Tissue enriched 21 cerebral cortex: 30.9 endometrium: 1.5 -IFIT1 G10P1, GARG-16, IFI56, IFNAI1 ENSG00000185745 Interferon-induced protein with tetratricopeptide repeats 1 10 89392546-89406486 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045980, HPA055380 Approved Supported Cytosol Expressed in all spleen: 61.6 -CXorf38 MGC39350 ENSG00000185753 Chromosome X open reading frame 38 X 40626921-40647554 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050120 Approved Supported Cytosol Expressed in all spleen: 22.4 -CLDN24 CLDN21 ENSG00000185758 Claudin 24 4 183321764-183322426 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 kidney: 1.0 smooth muscle: 0.2 -KCNQ5 Kv7.5 ENSG00000185760 Potassium channel, voltage gated KQT-like subfamily Q, member 5 6 72621792-73198851 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA016655 Approved Approved Vesicles Tissue enhanced 0 cerebral cortex: 22.4 thyroid gland: 7.8 -ADAMTSL5 THSD6 ENSG00000185761 ADAMTS-like 5 19 1505018-1513604 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044050 Uncertain Approved Golgi apparatus Tissue enhanced 0 cervix, uterine: 29.2 smooth muscle: 17.3 -KCNIP4 CALP, KCHIP4, MGC44947 ENSG00000185774 Kv channel interacting protein 4 4 20728616-21948799 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022862, HPA066717 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 57.4 cervix: 20.5 -SPATA31A6 FAM75A6 ENSG00000185775 SPATA31 subfamily A, member 6 9 42183659-42189882 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 16 testis: 1.5 adipose tissue: 0.0 -MORF4L1 Eaf3, HsT17725, MEAF3, MORFRG15, MRG15 ENSG00000185787 Mortality factor 4 like 1 15 78810487-78898133 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042360, HPA062010 Approved Supported Nuclear speckles Expressed in all testis: 1063.2 -NLRP9 CLR19.1, NALP9, NOD6, PAN12 ENSG00000185792 NLR family, pyrin domain containing 9 19 55708432-55738402 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042623 Uncertain Tissue enhanced 0 prostate: 1.5 testis: 0.6 -WDR53 MGC12928, MGC64882 ENSG00000185798 WD repeat domain 53 3 196554177-196568674 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA016420, HPA019332 Approved Approved Plasma membrane
Cytosol Tissue enriched 6 testis: 112.1 parathyroid gland: 19.5 -DMWD D19S593E, DMR-N9, gene59 ENSG00000185800 Dystrophia myotonica, WD repeat containing 19 45782947-45792802 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068172, HPA069843 Approved Approved Plasma membrane
Actin filaments Expressed in all cerebral cortex: 39.8 -SLC52A2 D15Ertd747e, FLJ11856, GPCR41, GPR172A, hRFT3, PAR1, RFVT2 ENSG00000185803 Solute carrier family 52 (riboflavin transporter), member 2 8 144354135-144361272 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063036 Approved Expressed in all placenta: 24.0 -PIGP DCRC, DSCR5, DSRC ENSG00000185808 Phosphatidylinositol glycan anchor biosynthesis, class P 21 37059170-37073170 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA026921 Uncertain Approved Vesicles Expressed in all epididymis: 123.4 -IKZF1 hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1 ENSG00000185811 IKAROS family zinc finger 1 (Ikaros) 7 50304124-50405101 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009247, HPA035221, HPA035222 Supported Approved Nucleoplasm
Nucleoli
Vesicles Tissue enhanced 0 lymph node: 84.0;tonsil: 58.0 appendix: 55.9 -PCYT2 ET ENSG00000185813 Phosphate cytidylyltransferase 2, ethanolamine 17 81900965-81911464 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023033, HPA023034 Supported Supported Intermediate filaments
Centrosome Expressed in all testis: 241.0 -NAT8L FLJ37478, Hcml3 ENSG00000185818 N-acetyltransferase 8-like (GCN5-related, putative) 4 2059512-2069089 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040677 Supported Mitochondria Group enriched 7 adipose tissue: 48.6;cerebral cortex: 65.1;testis: 19.0 kidney: 6.7 -OR6C76 ENSG00000185821 Olfactory receptor, family 6, subfamily C, member 76 12 55426254-55427192 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -NPAP1 C15orf2 ENSG00000185823 Nuclear pore associated protein 1 15 24675868-24683393 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA018828, HPA019562 Uncertain Tissue enriched 11 testis: 5.3 skin: 0.4 -BCAP31 6C6-Ag, BAP31, CDM, DXS1357E ENSG00000185825 B-cell receptor-associated protein 31 X 153700497-153724697 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003906, CAB015350, CAB015424 Supported Approved Validated Endoplasmic reticulum Expressed in all adipose tissue: 272.6 -ARL17A ARF1P2, ARL17P1 ENSG00000185829 ADP-ribosylation factor-like 17A 17 46516702-46579722 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046814 Uncertain Mixed endometrium: 13.3 -GNB1L GY2, WDR14 ENSG00000185838 Guanine nucleotide binding protein (G protein), beta polypeptide 1-like 22 19783224-19854939 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034627, HPA034628 Approved Approved Cytosol Mixed duodenum: 4.3 -DNAH14 C1orf67, DKFZp781B1548, Dnahc14, HL-18, HL18, MGC27277 ENSG00000185842 Dynein, axonemal, heavy chain 14 1 224896262-225399292 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027718, HPA028545, HPA031379 Uncertain Approved Centrosome Tissue enhanced 0 testis: 21.5 thyroid gland: 7.3 -CCDC190 C1orf110, MGC48998 ENSG00000185860 Coiled-coil domain containing 190 1 162824458-162868815 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028579, HPA028584, HPA028592 Uncertain Approved Vesicles Tissue enhanced 0 esophagus: 3.7;lung: 2.8 fallopian tube: 0.8 -EVI2B CD361, D17S376, EVDB ENSG00000185862 Ecotropic viral integration site 2B 17 31303766-31314112 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007436 Approved Tissue enhanced 0 spleen: 216.7 lymph node: 177.3 -TMEM210 ENSG00000185863 Transmembrane protein 210 9 137170858-137172409 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA066907 Supported Tissue enriched 11 testis: 10.5 salivary gland: 0.9 -NPIPB4 ENSG00000185864 Nuclear pore complex interacting protein family, member B4 16 21834569-21880827 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA053611 Approved Approved Nucleoplasm Expressed in all skin: 125.9 -ZNF829 DKFZp779O175 ENSG00000185869 Zinc finger protein 829 19 36888124-36916291 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA073073 Approved Nucleus
Nuclear bodies Tissue enriched 5 testis: 18.3 ovary: 3.3 -TMPRSS11B ENSG00000185873 Transmembrane protease, serine 11B 4 68226653-68245720 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 169 esophagus: 312.7;tonsil: 77.9 cervix: 1.1 -THNSL1 FLJ22002, TSH1 ENSG00000185875 Threonine synthase-like 1 10 25016658-25026664 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037585 Uncertain Approved Nuclear bodies
Mitochondria
Cytosol Mixed thyroid gland: 14.0 -TRIM69 RNF36, Trif, TRIMLESS ENSG00000185880 Tripartite motif containing 69 15 44728988-44767829 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028894 Supported Tissue enriched 17 testis: 56.8 cerebral cortex: 3.4 -ATP6V0C ATP6C, ATP6L, ATPL, VATL, Vma3 ENSG00000185883 ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 16 2513870-2520218 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065100 Approved Cytosol Expressed in all cerebral cortex: 424.2 -IFITM1 9-27, CD225, IFI17 ENSG00000185885 Interferon induced transmembrane protein 1 11 313506-315272 CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004810, CAB017615 Supported Supported Cytosol Expressed in all epididymis: 904.7 -PRSS38 MPN2 ENSG00000185888 Protease, serine, 38 1 227815693-227846470 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA028003, HPA055809 Supported Tissue enriched 21 testis: 4.2 epididymis: 0.2 -BPY2C VCY2C ENSG00000185894 Basic charge, Y-linked, 2C Y 25030901-25062548 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 testis: 2.1 gallbladder: 0.1 -LAMP1 CD107a ENSG00000185896 Lysosomal-associated membrane protein 1 13 113297241-113323672 CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004260, HPA014750 Supported Expressed in all thyroid gland: 210.9 -FFAR3 FFA3R, GPR41 ENSG00000185897 Free fatty acid receptor 3 19 35358460-35360485 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA044681 Uncertain Tissue enhanced 0 adipose tissue: 2.5;appendix: 3.6;smooth muscle: 2.2 gallbladder: 0.8 -TAS2R60 T2R60 ENSG00000185899 Taste receptor, type 2, member 60 7 143443453-143444409 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA030416 Uncertain Not detected parathyroid gland: 0.1 -POMK FLJ23356, SgK196 ENSG00000185900 Protein-O-mannose kinase 8 43093506-43123434 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013321 Uncertain Approved Nucleus
Cytosol Mixed cerebral cortex: 6.4 -C16orf54 FLJ35681 ENSG00000185905 Chromosome 16 open reading frame 54 16 29742463-29746006 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060546 Uncertain Tissue enhanced 0 bone marrow: 26.0 lymph node: 24.3 -KLHDC8B MGC35097 ENSG00000185909 Kelch domain containing 8B 3 49171611-49176486 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA008463, HPA014467 Supported Validated Cytosol Expressed in all adrenal gland: 70.3 -KLHL34 FLJ34960, RP11-450P7.3 ENSG00000185915 Kelch-like family member 34 X 21654690-21658330 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA060287 Uncertain Tissue enriched 8 skeletal muscle: 8.8 duodenum: 1.1 -SETD4 C21orf18, C21orf27 ENSG00000185917 SET domain containing 4 21 36034541-36079389 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA024073, HPA035405 Approved Approved Nuclear speckles Expressed in all testis: 41.7 -PTCH1 BCNS, NBCCS, PTCH ENSG00000185920 Patched 1 9 95442980-95517057 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB013717, HPA075072 Uncertain Approved Golgi apparatus Tissue enhanced 0 cervix, uterine: 41.6 endometrium: 27.2 -RTN4RL1 DKFZp547J144, NgR3, NGRH2 ENSG00000185924 Reticulon 4 receptor-like 1 17 1934677-2025345 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA044428 Uncertain Tissue enhanced 0 cerebral cortex: 12.5 skin: 6.2 -OR4C46 ENSG00000185926 Olfactory receptor, family 4, subfamily C, member 46 11 54603069-54603998 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -CALHM1 FAM26C ENSG00000185933 Calcium homeostasis modulator 1 10 103453387-103458888 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018317 Uncertain Tissue enhanced 0 cerebral cortex: 1.8 kidney: 0.6 -KRTAP5-5 KRTAP5-11, KRTAP5.5 ENSG00000185940 Keratin associated protein 5-5 11 1629775-1630707 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.1 -NKAIN3 FAM77D, FLJ39630 ENSG00000185942 Na+/K+ transporting ATPase interacting 3 8 62248591-62999652 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018833 Uncertain Not detected adrenal gland: 0.4 -RNPC3 FLJ20008, KIAA1839, RBM40, SNRNP65 ENSG00000185946 RNA-binding region (RNP1, RRM) containing 3 1 103525691-103555239 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052434 Supported Nucleoplasm Expressed in all epididymis: 65.9 -ZNF267 HZF2 ENSG00000185947 Zinc finger protein 267 16 31873758-31917357 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003866 Approved Approved Nucleoplasm Mixed appendix: 25.6 -IRS2 ENSG00000185950 Insulin receptor substrate 2 13 109752698-109786568 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016944, HPA054664 Approved Supported Aggresome
Cytosol Mixed bone marrow: 33.0 -C7orf61 IMAGE:4839025 ENSG00000185955 Chromosome 7 open reading frame 61 7 100456615-100464271 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA060395 Supported Approved Vesicles Tissue enriched 10 testis: 53.2 cerebral cortex: 5.2 -FAM186A LOC121006 ENSG00000185958 Family with sequence similarity 186, member A 12 50326230-50396622 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047128 Uncertain Tissue enriched 12 testis: 11.0 epididymis: 0.9 -SHOX GCFX, PHOG, SHOXY, SS ENSG00000185960 Short stature homeobox X 624344-659411 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA035141, HPA060931 Validated Nucleoplasm
Vesicles Mixed spleen: 1.1 -LCE3A LEP13 ENSG00000185962 Late cornified envelope 3A 1 152622834-152623103 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 23 tonsil: 101.7 esophagus: 4.5 -BICD2 KIAA0699 ENSG00000185963 Bicaudal D homolog 2 (Drosophila) 9 92711363-92764812 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023013, HPA024452 Supported Supported Golgi apparatus
Plasma membrane
Cytosol Expressed in all skin: 69.4 -LCE3E LEP17 ENSG00000185966 Late cornified envelope 3E 1 152565654-152566772 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 36 esophagus: 9.6;skin: 9.0;tonsil: 18.9 breast: 0.3 -CCIN BTBD20, KBTBD14 ENSG00000185972 Calicin 9 36169394-36171334 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 41 testis: 111.6 smooth muscle: 2.7 -TMLHE BBOX2, FLJ10727, TMLH, XAP130 ENSG00000185973 Trimethyllysine hydroxylase, epsilon X 155490115-155669944 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034589, HPA040331 Approved Supported Mitochondria Expressed in all parathyroid gland: 30.8 -GRK1 GPRK1, RHOK, RK ENSG00000185974 G protein-coupled receptor kinase 1 13 113667155-113737735 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035200, HPA059376 Supported Not detected thyroid gland: 0.8 -DEFB128 DEFB-28 ENSG00000185982 Defensin, beta 128 20 187853-189681 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 16814 epididymis: 1681.4 adipose tissue: 0.0 -SLITRK2 CXorf2, KIAA1854, SLITL1 ENSG00000185985 SLIT and NTRK-like family, member 2 X 145817832-145825842 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 25.7 seminal vesicle: 7.3 -PLK5 PLK5P, SgK384ps ENSG00000185988 Polo-like kinase 5 19 1524074-1535456 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA035024 Approved Tissue enhanced 0 cervix, uterine: 4.5;endometrium: 4.7;testis: 6.9 epididymis: 3.3 -RASA3 GAP1IP4BP, GAPIII ENSG00000185989 RAS p21 protein activator 3 13 113977783-114132611 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046759 Approved Mixed lymph node: 17.9 -LRCH3 MGC4126 ENSG00000186001 Leucine-rich repeats and calponin homology (CH) domain containing 3 3 197791226-197888436 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012380, HPA017299 Uncertain Validated Cytosol Expressed in all testis: 26.2 -LEMD1 CT50, LEMP-1 ENSG00000186007 LEM domain containing 1 1 205381378-205457091 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045425 Approved Nucleoli
Cytosol Group enriched 17 epididymis: 17.7;testis: 71.0 fallopian tube: 2.6 -ATP4B ATP6B ENSG00000186009 ATPase, H+/K+ exchanging, beta polypeptide 13 113648804-113658186 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045400, HPA052649 Supported Tissue enriched 85 stomach: 919.0 fallopian tube: 10.8 -NDUFA13 B16.6, CDA016, CGI-39, GRIM-19, GRIM19 ENSG00000186010 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 19 19515736-19529054 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041213 Supported Validated Mitochondria Expressed in all heart muscle: 220.4 -ZNF566 FLJ14779, MGC12515 ENSG00000186017 Zinc finger protein 566 19 36445119-36489902 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023456 Uncertain Approved Nucleus Mixed thyroid gland: 8.0 -ZNF529 KIAA1615 ENSG00000186020 Zinc finger protein 529 19 36534774-36605276 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA031311 Uncertain Approved Nucleoplasm Mixed testis: 18.2 -ZNF284 DKFZp781F1775 ENSG00000186026 Zinc finger protein 284 19 44072144-44089613 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed skin: 3.6 -HTR3E ENSG00000186038 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 3 184097064-184106995 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049764 Supported Tissue enhanced 0 duodenum: 1.0 small intestine: 0.8 -DLEU7 FLJ44882 ENSG00000186047 Deleted in lymphocytic leukemia, 7 13 50711008-50843939 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053750 Uncertain Tissue enriched 6 cerebral cortex: 6.3 epididymis: 1.0 -KRT73 K6IRS3, KRT6IRS3 ENSG00000186049 Keratin 73, type II 12 52607570-52618559 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044031 Supported Group enriched 7 lymph node: 2.6;skin: 12.2 appendix: 1.0 -TAL2 bHLHa19 ENSG00000186051 T-cell acute lymphocytic leukemia 2 9 105662457-105663112 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA030886 Uncertain Approved Cytosol Group enriched 5 kidney: 3.4;skeletal muscle: 4.8 epididymis: 0.8 -AIDA C1orf80, FLJ12806 ENSG00000186063 Axin interactor, dorsalization associated 1 222668013-222713210 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027935 Approved Approved Microtubules
Cytokinetic bridge
Cytosol Expressed in all testis: 79.9 -C15orf41 FLJ22851, HH114, MGC11326 ENSG00000186073 Chromosome 15 open reading frame 41 15 36579611-36810248 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061023 Uncertain Approved Nucleoplasm Tissue enhanced 0 heart muscle: 51.7 smooth muscle: 14.0 -CD300LF CD300f, CLM1, IGSF13, IREM1, NKIR ENSG00000186074 CD300 molecule-like family member f 17 74694311-74712978 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013712 Supported Tissue enhanced 0 lung: 25.6;spleen: 28.6 appendix: 18.8 -ZPBP2 MGC41930, ZPBPL ENSG00000186075 Zona pellucida binding protein 2 17 39868164-39877896 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA027997, HPA053070 Supported Tissue enriched 214 testis: 208.2 tonsil: 0.9 -KRT5 EBS2, KRT5A ENSG00000186081 Keratin 5, type II 12 52514575-52520687 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000027, CAB000129, HPA059479 Supported Group enriched 9 esophagus: 3269.5;skin: 6006.7 tonsil: 537.4 -NBPF6 ENSG00000186086 Neuroblastoma breakpoint family, member 6 1 108375799-108471002 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045044, HPA046411, HPA047447, HPA058050 Uncertain Tissue enriched 6 testis: 5.4 small intestine: 0.9 -GSAP LOC54103, PION ENSG00000186088 Gamma-secretase activating protein 7 77310751-77416400 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023994 Supported Vesicles Mixed lung: 26.8 -HTR3D ENSG00000186090 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic 3 184031544-184039369 Predicted membrane proteins, Transporters Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.0 -OR4F5 ENSG00000186092 Olfactory receptor, family 4, subfamily F, member 5 1 69091-70008 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -AGBL4 CCP6, FLJ14442 ENSG00000186094 ATP/GTP binding protein-like 4 1 48532855-50023913 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037994 Approved Tissue enhanced 0 cerebral cortex: 7.9 fallopian tube: 4.6 -ARGFX ENSG00000186103 Arginine-fifty homeobox 3 121570704-121586634 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA043049 Uncertain Not detected testis: 0.6 -CYP2R1 ENSG00000186104 Cytochrome P450, family 2, subfamily R, polypeptide 1 11 14877440-14892252 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042949 Approved Mixed skin: 8.1 -LRRC70 LOC100130733, SLRN ENSG00000186105 Leucine rich repeat containing 70 5 62578735-62581448 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA013409 Uncertain Mixed thyroid gland: 6.4 -ANKRD46 ENSG00000186106 Ankyrin repeat domain 46 8 100509752-100559784 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013758 Approved Approved Cytosol Expressed in all cerebral cortex: 70.6 -PIP5K1C KIAA0589, LCCS3, PIP5Kgamma ENSG00000186111 Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 19 3630183-3700479 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017168 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 53.0 -OR5D14 ENSG00000186113 Olfactory receptor, family 5, subfamily D, member 14 11 55795556-55796500 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -CYP4F2 ENSG00000186115 Cytochrome P450, family 4, subfamily F, polypeptide 2 19 15878023-15898120 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014048, HPA017265, HPA058960 Supported Group enriched 6 duodenum: 80.4;epididymis: 27.5;kidney: 39.1;liver: 84.6;small intestine: 86.1 prostate: 10.6 -OR5L1 OST262 ENSG00000186117 Olfactory receptor, family 5, subfamily L, member 1 (gene/pseudogene) 11 55811467-55812402 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA047524 Uncertain Not detected epididymis: 0.0 -TEX38 ATPAF1-AS1, C1orf223, LOC374973, THEG4 ENSG00000186118 Testis expressed 38 1 46668855-46673594 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 127 testis: 260.0 parathyroid gland: 2.0 -OR5D18 ENSG00000186119 Olfactory receptor, family 5, subfamily D, member 18 11 55819630-55820571 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -ZBTB6 ZID, ZNF482 ENSG00000186130 Zinc finger and BTB domain containing 6 9 122908056-122913330 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA054111, HPA076894 Approved Approved Nucleoplasm
Mitochondria Mixed thyroid gland: 12.5 -C2orf76 AIM29, LOC130355, MGC104437 ENSG00000186132 Chromosome 2 open reading frame 76 2 119302225-119366828 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044977, HPA055362 Uncertain Approved Endoplasmic reticulum Expressed in all epididymis: 52.2 -TAS2R42 hT2R55, T2R24, T2R55, TAS2R55 ENSG00000186136 Taste receptor, type 2, member 42 12 11185993-11186937 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA036149 Uncertain Approved Nucleoplasm
Actin filaments
Focal adhesion sites Not detected epididymis: 0.0 -POLR3C RPC3, RPC62 ENSG00000186141 Polymerase (RNA) III (DNA directed) polypeptide C (62kD) 1 145824088-145842505 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027508, HPA027516 Uncertain Validated Nucleoplasm Expressed in all testis: 53.0 -PRR30 C2orf53, MGC44505 ENSG00000186143 Proline rich 30 2 27136848-27139410 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 1039 testis: 103.8 epididymis: 0.0 -DEFB131 DEFB-31 ENSG00000186146 Defensin, beta 131 4 9444534-9450514 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 9 epididymis: 203.3 seminal vesicle: 21.7 -UBL4B FLJ25690 ENSG00000186150 Ubiquitin-like 4B 1 110112468-110113945 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA031364 Supported Uncertain Intermediate filaments
Mitochondria Tissue enriched 62 testis: 69.1 fallopian tube: 1.1 -WWOX FOR, SDR41C1, WOX1 ENSG00000186153 WW domain containing oxidoreductase 16 78099413-79212667 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050992 Approved Supported Golgi apparatus
Cytosol Expressed in all thyroid gland: 33.2 -CYP4Z1 CYP4A20 ENSG00000186160 Cytochrome P450, family 4, subfamily Z, polypeptide 1 1 47067488-47118319 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 breast: 7.0 lung: 1.7 -CCDC84 DLNB14 ENSG00000186166 Coiled-coil domain containing 84 11 118998142-119015791 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039906, HPA071715 Uncertain Approved Nucleus Mixed skin: 4.6 -BCL9L DLNB11 ENSG00000186174 B-cell CLL/lymphoma 9-like 11 118893875-118925608 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049370, HPA053421 Uncertain Validated Nucleoplasm Expressed in all placenta: 34.8 -POLR1D MGC9850, RPA16, RPA9, RPAC2, RPO1-3 ENSG00000186184 Polymerase (RNA) I polypeptide D, 16kDa 13 27620742-27667415 Disease related genes, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039337 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all testis: 107.5 -KIF18B ENSG00000186185 Kinesin family member 18B 17 44924709-44947711 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024205, HPA027831 Supported Supported Nucleus
Microtubule ends
Cytosol Mixed bone marrow: 8.4 -ZNRF1 DKFZp434E229, FLJ14846, nin283 ENSG00000186187 Zinc and ring finger 1, E3 ubiquitin protein ligase 16 74999030-75110994 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027470 Approved Expressed in all testis: 34.2 -FFAR4 GPR120, GPR129, O3FAR1, PGR4 ENSG00000186188 Free fatty acid receptor 4 10 93566665-93604480 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042563 Uncertain Uncertain Plasma membrane Tissue enhanced 0 colon: 8.6;rectum: 12.9 lung: 5.5 -BPIFB3 C20orf185, dJ726C3.4, LPLUNC3, RYA3 ENSG00000186190 BPI fold containing family B, member 3 20 33055424-33073628 Plasma proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045741 Uncertain Tissue enhanced 0 testis: 1.0 salivary gland: 0.2 -BPIFB4 C20orf186, dJ726C3.5, LPLUNC4 ENSG00000186191 BPI fold containing family B, member 4 20 33079644-33111751 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 parathyroid gland: 1.3 testis: 0.7 -SAPCD2 C9orf140, p42.3 ENSG00000186193 Suppressor APC domain containing 2 9 137062124-137070588 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044154 Approved Supported Nucleus
Nucleoli
Cytosol Tissue enhanced 0 cerebral cortex: 12.9 small intestine: 4.9 -EDARADD ENSG00000186197 EDAR-associated death domain 1 236348262-236484914 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018836 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 urinary bladder: 18.7 seminal vesicle: 10.9 -SLC51B OSTbeta ENSG00000186198 Solute carrier family 51, beta subunit 15 65045370-65053396 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA008398, HPA008533 Supported Approved Vesicles
Mitochondria Tissue enhanced 0 duodenum: 87.8;small intestine: 120.6 cervix: 63.7 -CYP4F12 ENSG00000186204 Cytochrome P450, family 4, subfamily F, polypeptide 12 19 15672757-15697174 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058960 Approved Tissue enhanced 0 duodenum: 37.1;small intestine: 43.1 skin: 22.4 -MARC1 FLJ22390, MOSC1 ENSG00000186205 Mitochondrial amidoxime reducing component 1 1 220786759-220819657 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028702 Approved Supported Mitochondria Expressed in all adipose tissue: 225.6 -LCE5A LEP18, SPRL5A ENSG00000186207 Late cornified envelope 5A 1 152510844-152512177 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 skin: 94.0 breast: 16.5 -SOWAHB ANKRD56 ENSG00000186212 Sosondowah ankyrin repeat domain family member B 4 76894928-76898147 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA036809, HPA036810 Approved Approved Nucleoli fibrillar center Mixed small intestine: 9.0 -BLOC1S4 BCAS4L, CNO, FLJ11230 ENSG00000186222 Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 4 6716055-6717671 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043840 Approved Approved Vesicles
Cytosol Expressed in all ovary: 12.7 -LCE1E LEP5 ENSG00000186226 Late cornified envelope 1E 1 152786214-152788426 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 122 skin: 74.1 breast: 0.6 -ZNF749 FLJ16360 ENSG00000186230 Zinc finger protein 749 19 57435329-57445485 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042082, HPA042091, HPA056001 Uncertain Approved Nucleoplasm
Nuclear membrane Mixed parathyroid gland: 4.2 -KLHL32 BKLHD5, KIAA1900 ENSG00000186231 Kelch-like family member 32 6 96924620-97140754 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039150 Approved Group enriched 6 cerebral cortex: 25.4;fallopian tube: 10.2 testis: 3.1 -MKL2 FLJ31823, MRTF-B ENSG00000186260 MKL/myocardin-like 2 16 14071321-14266773 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011286 Supported Supported Nuclear speckles Expressed in all cerebral cortex: 50.3 -BTLA BTLA1, CD272 ENSG00000186265 B and T lymphocyte associated 3 112463968-112499561 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047211, HPA062029 Supported Group enriched 7 appendix: 14.7;lymph node: 29.6;spleen: 14.8;tonsil: 25.7 urinary bladder: 3.1 -ZNF17 FLJ40864, FLJ46058, FLJ46615, HPF3, KIAA1947, KOX10 ENSG00000186272 Zinc finger protein 17 19 57411163-57421939 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed parathyroid gland: 9.0 -KDM4D FLJ10251, JMJD2D ENSG00000186280 Lysine (K)-specific demethylase 4D 11 94973681-94999518 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055854, HPA064037 Approved Approved Nucleoplasm Tissue enriched 30 testis: 60.6 parathyroid gland: 2.0 -GPAT2 CT123 ENSG00000186281 Glycerol-3-phosphate acyltransferase 2, mitochondrial 2 96021946-96039451 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036841 Uncertain Approved Mitochondria Mixed testis: 7.3 -TOR3A ADIR, ADIR2, FLJ22345 ENSG00000186283 Torsin family 3, member A 1 179081377-179098023 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028766 Approved Expressed in all lymph node: 42.8 -PABPC1L2A RBM32A ENSG00000186288 Poly(A) binding protein, cytoplasmic 1-like 2A X 73077276-73079512 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041573 Approved Group enriched 5 adrenal gland: 2.0;cerebral cortex: 6.7;prostate: 3.7;testis: 2.8 epididymis: 0.7 -GABRA5 ENSG00000186297 Gamma-aminobutyric acid (GABA) A receptor, alpha 5 15 26866363-26949207 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA077031 Supported Cell Junctions Tissue enriched 43 cerebral cortex: 82.0 esophagus: 1.8 -PPP1CC PP1C, PP1gamma ENSG00000186298 Protein phosphatase 1, catalytic subunit, gamma isozyme 12 110719680-110742939 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022645 Uncertain Expressed in all testis: 256.1 -ZNF555 MGC26707 ENSG00000186300 Zinc finger protein 555 19 2841435-2860484 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA053956, HPA055430 Uncertain Mixed testis: 10.5 -OR10T2 ENSG00000186306 Olfactory receptor, family 10, subfamily T, member 2 1 158398522-158399466 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Not detected epididymis: 0.0 -NAP1L3 MB20, MGC26312, NPL3 ENSG00000186310 Nucleosome assembly protein 1-like 3 X 93670930-93673568 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026075 Approved Vesicles Tissue enhanced 0 cerebral cortex: 131.7 testis: 31.0 -PRELID2 FLJ38376, MGC21644 ENSG00000186314 PRELI domain containing 2 5 145471799-145835369 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042486 Uncertain Approved Nucleoplasm Tissue enhanced 0 small intestine: 29.3 rectum: 19.5 -BACE1 BACE ENSG00000186318 Beta-site APP-cleaving enzyme 1 11 117285207-117316259 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016358 Approved Supported Plasma membrane Expressed in all pancreas: 100.6 -RGS9BP FLJ45744, PERRS, R9AP, RGS9 ENSG00000186326 Regulator of G protein signaling 9 binding protein 19 32675407-32678300 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 6 skeletal muscle: 2.6 lung: 0.4 -TMEM212 FLJ23172 ENSG00000186329 Transmembrane protein 212 3 171843349-171938715 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045736, HPA053134 Uncertain Approved Nucleoli fibrillar center
Endoplasmic reticulum Tissue enriched 6 fallopian tube: 47.9 lung: 7.7 -SLC36A3 PAT3, TRAMD2, tramdorin2 ENSG00000186334 Solute carrier family 36, member 3 5 151276762-151303766 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 57 testis: 14.4 epididymis: 0.2 -SLC36A2 PAT2, TRAMD1, tramdorin ENSG00000186335 Solute carrier family 36 (proton/amino acid symporter), member 2 5 151314978-151347590 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044002, HPA062229 Supported Group enriched 26 kidney: 67.2;skeletal muscle: 28.1 testis: 1.8 -THBS2 TSP2 ENSG00000186340 Thrombospondin 2 6 169215780-169254044 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB017716, HPA044304 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Tissue enhanced 0 gallbladder: 113.8 endometrium: 71.0 -RXRA NR2B1 ENSG00000186350 Retinoid X receptor, alpha 9 134317098-134440585 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004565, CAB005352 Supported Supported Nucleus
Golgi apparatus Mixed esophagus: 25.9 -ANKRD37 Lrp2bp ENSG00000186352 Ankyrin repeat domain 37 4 185396021-185400628 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA036626, HPA058127 Uncertain Supported Nucleus
Mitochondria
Cytosol Mixed prostate: 31.3 -C9orf47 bA791O21.3, C9orf108, FLJ37523 ENSG00000186354 Chromosome 9 open reading frame 47 9 88990863-88996140 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB009902 Approved Mixed adrenal gland: 2.1 -NUDT17 FLJ34433 ENSG00000186364 Nudix (nucleoside diphosphate linked moiety X)-type motif 17 1 145845629-145848953 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA030145 Approved Approved Centrosome
Cytosol Mixed testis: 5.2 -KIAA1024L ENSG00000186367 KIAA1024-like 5 129748079-129766732 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA013760 Uncertain Tissue enriched 11 skeletal muscle: 11.5 testis: 1.0 -ZNF75D D8C6, ZKSCAN24, ZNF75, ZNF82, ZSCAN28 ENSG00000186376 Zinc finger protein 75D X 135248920-135344087 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA004705 Supported Approved Nucleoplasm
Golgi apparatus Expressed in all prostate: 16.1 -CYP4X1 MGC40051 ENSG00000186377 Cytochrome P450, family 4, subfamily X, polypeptide 1 1 47023568-47050751 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA017661 Approved Tissue enhanced 0 cervix, uterine: 52.7 breast: 18.6 -KRT26 KRT25B ENSG00000186393 Keratin 26, type I 17 40766238-40772162 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026890 Supported Tissue enhanced 0 testis: 1.1 bone marrow: 0.9 -KRT10 CK10, K10, KPP ENSG00000186395 Keratin 10, type I 17 40818117-40822595 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000132, HPA012014 Supported Tissue enriched 32 skin: 18560.3 breast: 577.6 -GOLGA8R ENSG00000186399 Golgin A8 family, member R 15 30403740-30414162 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 thyroid gland: 13.4 testis: 6.8 -OR10X1 OR10X1P ENSG00000186400 Olfactory receptor, family 10, subfamily X, member 1 (gene/pseudogene) 1 158578919-158579899 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA060990 Uncertain Not detected epididymis: 0.0 -CD300E CD300LE, CLM2, IREM2 ENSG00000186407 CD300e molecule 17 74609887-74623738 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015570 Uncertain Tissue enhanced 0 appendix: 53.9;bone marrow: 29.0 adipose tissue: 17.9 -CCDC30 FLJ20972, LOC728621, PFD6L ENSG00000186409 Coiled-coil domain containing 30 1 42463330-42654664 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036344, HPA036345 Approved Tissue enhanced 0 testis: 6.8 fallopian tube: 4.9 -NKRF ITBA4, NRF ENSG00000186416 NFKB repressing factor X 119588337-119605895 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001476 Supported Nucleus
Nucleoli Mixed cerebral cortex: 20.4 -GLDN CLOM, COLM, colmedin, CRG-L2, UNC-112 ENSG00000186417 Gliomedin 15 51341629-51408013 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA059441 Uncertain Tissue enhanced 0 cerebral cortex: 24.0 adipose tissue: 12.9 -FCAR CD89 ENSG00000186431 Fc fragment of IgA receptor 19 54874248-54890472 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014050 Approved Supported Plasma membrane Tissue enriched 15 bone marrow: 20.8 appendix: 1.4 -KPNA4 IPOA3, MGC12217, MGC26703, QIP1, SRP3 ENSG00000186432 Karyopherin alpha 4 (importin alpha 3) 3 160494995-160565588 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034336, HPA043154, HPA045500 Supported Validated Nucleus Expressed in all skeletal muscle: 36.6 -TRDN ENSG00000186439 Triadin 6 123216339-123637093 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038226, HPA058226 Supported Approved Plasma membrane
Cytosol Group enriched 25 heart muscle: 254.8;skeletal muscle: 650.4 prostate: 18.2 -OR6P1 ENSG00000186440 Olfactory receptor, family 6, subfamily P, member 1 1 158562651-158563604 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA047466 Uncertain Not detected epididymis: 0.0 -KRT3 CK3, K3 ENSG00000186442 Keratin 3, type II 12 52789685-52796117 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 esophagus: 1.3;skin: 1.8 tonsil: 0.2 -ZNF501 MGC21738, ZNF52 ENSG00000186446 Zinc finger protein 501 3 44729596-44737083 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044161 Uncertain Approved Endoplasmic reticulum Mixed testis: 2.7 -ZNF197 D3S1363E, P18, ZKSCAN9, ZNF166, ZSCAN41 ENSG00000186448 Zinc finger protein 197 3 44584888-44648471 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054567 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 9.2 -SPATA12 ENSG00000186451 Spermatogenesis associated 12 3 57060441-57075432 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043323 Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enriched 54 testis: 22.9 lung: 0.4 -TMPRSS12 CT151, MGC57341 ENSG00000186452 Transmembrane (C-terminal) protease, serine 12 12 50842920-50887884 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 61 testis: 39.3 epididymis: 0.6 -FAM228A C2orf84, FLJ30851 ENSG00000186453 Family with sequence similarity 228, member A 2 24175069-24200849 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 19 testis: 42.1 cerebral cortex: 2.2 -DEFB132 DEFB32, RP5-1103G7.6 ENSG00000186458 Defensin, beta 132 20 257736-261096 Predicted secreted proteins Evidence at protein level Evidence at protein level No evidence HPA046399 Supported Tissue enriched 11 epididymis: 326.7 seminal vesicle: 28.8 -NAP1L2 BPX, MGC26243 ENSG00000186462 Nucleosome assembly protein 1-like 2 X 73212299-73214848 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054050, HPA057065 Validated Vesicles
Plasma membrane
Cytosol Tissue enriched 5 cerebral cortex: 90.3 parathyroid gland: 17.6 -RPS23 S23 ENSG00000186468 Ribosomal protein S23 5 82273358-82278577 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054853 Approved Validated Endoplasmic reticulum
Cytosol Expressed in all ovary: 4311.4 -GNG2 ENSG00000186469 Guanine nucleotide binding protein (G protein), gamma 2 14 51826195-51979342 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003534, CAB018380 Uncertain Supported Approved Golgi apparatus
Vesicles Expressed in all testis: 184.7 -BTN3A2 BTN3.2 ENSG00000186470 Butyrophilin, subfamily 3, member A2 6 26365159-26378320 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019392 Uncertain Expressed in all spleen: 131.4 -AKAP14 AKAP28 ENSG00000186471 A kinase (PRKA) anchor protein 14 X 119895837-119920716 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA060999 Supported Group enriched 14 fallopian tube: 67.0;testis: 72.6 lung: 4.8 -PCLO ACZ, DKFZp779G1236, KIAA0559 ENSG00000186472 Piccolo presynaptic cytomatrix protein 7 82754013-83162930 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015858, HPA029579 Approved Approved Nuclear speckles
Plasma membrane Tissue enhanced 0 cerebral cortex: 17.5 parathyroid gland: 9.6 -KLK12 KLK-L5 ENSG00000186474 Kallikrein-related peptidase 12 19 51029092-51035230 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB025473 Uncertain Tissue enhanced 0 esophagus: 32.6 tonsil: 8.6 -RGS7BP R7BP ENSG00000186479 Regulator of G-protein signaling 7 binding protein 5 64506257-64612312 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039600 Approved Tissue enhanced 0 cerebral cortex: 39.0 fallopian tube: 13.1 -INSIG1 CL-6, MGC1405 ENSG00000186480 Insulin induced gene 1 7 155297776-155310235 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA071524 Approved Vesicles Expressed in all liver: 281.1 -MYT1L KIAA1106, NZF1, ZC2HC4B ENSG00000186487 Myelin transcription factor 1-like 2 1789113-2331260 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 11 cerebral cortex: 60.2 testis: 5.3 -C5orf38 CEI, IRX2NB ENSG00000186493 Chromosome 5 open reading frame 38 5 2752131-2755397 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA073667 Validated Golgi apparatus
Vesicles Tissue enhanced 0 lung: 13.8;salivary gland: 13.0 skin: 8.5 -ZNF396 FLJ31213, ZSCAN14 ENSG00000186496 Zinc finger protein 396 18 35366697-35377337 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA006686 Uncertain Mixed thyroid gland: 14.4 -TMEM222 C1orf160, DKFZP564D0478 ENSG00000186501 Transmembrane protein 222 1 27322145-27336400 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016579, HPA059374 Approved Approved Plasma membrane
Cytosol Expressed in all fallopian tube: 47.4 -OR9Q1 ENSG00000186509 Olfactory receptor, family 9, subfamily Q, member 1 11 58023881-58181616 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected skeletal muscle: 0.1 -CLCNKA hClC-Ka ENSG00000186510 Chloride channel, voltage-sensitive Ka 1 16018875-16034050 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA057717 Approved Group enriched 9 kidney: 63.9;parathyroid gland: 39.6 thyroid gland: 5.5 -OR9Q2 OR9Q2P ENSG00000186513 Olfactory receptor, family 9, subfamily Q, member 2 11 58190434-58191518 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.2 -ARHGAP30 FLJ00267 ENSG00000186517 Rho GTPase activating protein 30 1 161046946-161069970 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036300 Uncertain Supported Vesicles Tissue enhanced 0 lymph node: 87.3;spleen: 82.0 appendix: 75.4 -SEPT10 FLJ11619 ENSG00000186522 Septin 10 2 109542982-109614206 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047860, HPA056304, HPA060310 Approved Validated Actin filaments Mixed testis: 140.3 -FAM86B1 MGC16279 ENSG00000186523 Family with sequence similarity 86, member B1 8 12182096-12194133 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041610, HPA055718 Uncertain Uncertain Vesicles Tissue enhanced 0 epididymis: 9.2 cerebral cortex: 4.5 -CYP4F8 ENSG00000186526 Cytochrome P450, family 4, subfamily F, polypeptide 8 19 15615218-15630638 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058960 Approved Tissue enriched 51 seminal vesicle: 145.8 prostate: 2.8 -CYP4F3 CYP4F, LTB4H ENSG00000186529 Cytochrome P450, family 4, subfamily F, polypeptide 3 19 15615617-15662825 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058960 Approved Tissue enhanced 0 bone marrow: 53.2;liver: 98.0 kidney: 29.2 -SMYD4 KIAA1936, ZMYND21 ENSG00000186532 SET and MYND domain containing 4 17 1779485-1830634 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030059 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles
Cytosol Expressed in all testis: 10.9 -DEFB105A DEFB-5, DEFB105 ENSG00000186562 Defensin, beta 105A 8 7821966-7823889 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6001 epididymis: 2329.8 esophagus: 0.3 -FOXD2 FKHL17, FREAC9 ENSG00000186564 Forkhead box D2 1 47436017-47440691 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 colon: 3.8;rectum: 3.5 prostate: 1.1 -GPATCH8 GPATC8, KIAA0553 ENSG00000186566 G patch domain containing 8 17 44395284-44503430 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044380 Approved Approved Nuclear speckles
Mitochondria Mixed parathyroid gland: 11.4 -CEACAM19 CEAL1 ENSG00000186567 Carcinoembryonic antigen-related cell adhesion molecule 19 19 44662278-44684359 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014462, HPA052865 Uncertain Approved Nucleus
Nucleoli
Mitochondria Mixed skin: 12.7 -DEFB107A DEFB-7, DEFB107 ENSG00000186572 Defensin, beta 107A 8 7811720-7815716 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045626 Approved Tissue enriched 2765 epididymis: 478.6 endometrium: 0.1 -NF2 merlin ENSG00000186575 Neurofibromin 2 (merlin) 22 29603556-29698598 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003097, CAB005385 Supported Validated Nucleus
Plasma membrane
Cytosol Expressed in all parathyroid gland: 57.6 -C6orf1 LBH, MGC57858 ENSG00000186577 Chromosome 6 open reading frame 1 6 34246380-34249470 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037659, HPA037660 Uncertain Expressed in all cerebral cortex: 70.1 -DEFB106A DEFB-6, DEFB106 ENSG00000186579 Defensin, beta 106A 8 7825172-7829053 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045592 Supported Not detected adipose tissue: 0.0 -SPATC1 MGC61633, SPATA15, SPERIOLIN ENSG00000186583 Spermatogenesis and centriole associated 1 8 144012414-144047085 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039590, HPA040220 Uncertain Group enriched 5 bone marrow: 6.2;testis: 21.8 appendix: 2.6 -UBE2H GID3, UBC8, UBCH ENSG00000186591 Ubiquitin-conjugating enzyme E2H 7 129830732-129952949 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003302 Approved Supported Mitochondria Expressed in all parathyroid gland: 92.9 -DEFB105B ENSG00000186599 Defensin, beta 105B 8 7487669-7489593 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12711 epididymis: 1768.6 testis: 0.1 -HPDL 4-HPPD-L, GLOXD1, MGC15668 ENSG00000186603 4-hydroxyphenylpyruvate dioxygenase-like 1 45326905-45328533 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031997, HPA057346 Approved Supported Mitochondria Mixed colon: 3.9 -KATNA1 ENSG00000186625 Katanin p60 (ATPase containing) subunit A 1 6 149594873-149648972 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036207 Approved Supported Nucleus
Microtubule organizing center Expressed in all testis: 80.4 -FSD2 RP11-127F21, SPRYD1 ENSG00000186628 Fibronectin type III and SPRY domain containing 2 15 82755362-82806070 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046263 Approved Cytosol Group enriched 18 heart muscle: 37.5;skeletal muscle: 53.5 epididymis: 2.5 -ARAP1 CENTD2 ENSG00000186635 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 11 72685069-72793599 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020703, HPA070383 Approved Approved Nucleoplasm
Vesicles
Plasma membrane
Cytosol Expressed in all spleen: 92.9 -KIF24 bA571F15.4, C9orf48, FLJ10933, FLJ43884 ENSG00000186638 Kinesin family member 24 9 34252381-34329200 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020643 Uncertain Tissue enhanced 0 testis: 19.9 fallopian tube: 5.0 -PDE2A ENSG00000186642 Phosphodiesterase 2A, cGMP-stimulated 11 72576141-72674591 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009752, HPA031192 Approved Supported Cytosol Tissue enhanced 0 cerebral cortex: 142.1;spleen: 187.4 adipose tissue: 61.9 -LRRC16B BC008134, C14orf121, CARMIL3, crml-1 ENSG00000186648 Leucine rich repeat containing 16B 14 24052000-24069728 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030596 Uncertain Tissue enhanced 0 cerebral cortex: 6.8;skin: 6.2 testis: 3.0 -PRG2 BMPG, MBP ENSG00000186652 Proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 11 57386794-57390657 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038515 Supported Tissue enriched 29 placenta: 3847.6 bone marrow: 130.5 -PRR5 FLJ20185k, PP610, Protor-1 ENSG00000186654 Proline rich 5 (renal) 22 44668547-44737681 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054072 Approved Mixed spleen: 17.9 -ZFP91 PZF, ZNF757 ENSG00000186660 ZFP91 zinc finger protein 11 58579111-58621042 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024037, CAB025417, HPA065325 Approved Supported Nucleus
Nucleoli Expressed in all testis: 175.0 -C17orf58 ENSG00000186665 Chromosome 17 open reading frame 58 17 67991101-67993649 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA023036 Uncertain Approved Plasma membrane
Cytosol Expressed in all placenta: 58.5 -BCDIN3D ENSG00000186666 BCDIN3 domain containing 12 49836039-49843129 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039911 Approved Supported Nucleus
Cytosol Mixed parathyroid gland: 7.7 -MAGEE2 HCA3 ENSG00000186675 Melanoma antigen family E2 X 75782988-75785236 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030625 Uncertain Tissue enhanced 0 cerebral cortex: 3.3 adrenal gland: 1.0 -CYP27C1 FLJ16008 ENSG00000186684 Cytochrome P450, family 27, subfamily C, polypeptide 1 2 127184120-127220078 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA068731 Approved Vesicles Tissue enhanced 0 skin: 7.0 cervix: 2.4 -LYRM7 C5orf31, FLJ20796, MZM1L ENSG00000186687 LYR motif containing 7 5 131170810-131205426 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050053 Approved Mixed testis: 29.7 -CFAP73 CCDC42B, MIA2 ENSG00000186710 Cilia and flagella associated protein 73 12 113149858-113159276 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA048539 Supported Tissue enriched 8 fallopian tube: 59.6 lung: 7.0 -CCDC73 NY-SAR-79 ENSG00000186714 Coiled-coil domain containing 73 11 32602246-32794658 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038668, HPA038669 Uncertain Tissue enriched 11 testis: 6.6 spleen: 0.5 -BCR ALL, BCR1, CML, D22S11, D22S662, PHL ENSG00000186716 Breakpoint cluster region 22 23179704-23318037 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010421, CAB018545, HPA038337 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 48.5 -OR10H1 ENSG00000186723 Olfactory receptor, family 10, subfamily H, member 1 19 15807003-15808126 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected urinary bladder: 0.7 -MPPED1 239AB, C22orf1, FAM1A ENSG00000186732 Metallophosphoesterase domain containing 1 22 43411196-43507848 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 9 cerebral cortex: 39.5 liver: 4.2 -FSCN2 RFSN, RP30 ENSG00000186765 Fascin actin-bundling protein 2, retinal 17 81528396-81537130 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 parathyroid gland: 4.3;thyroid gland: 2.9 salivary gland: 0.8 -FOXI2 FLJ46831 ENSG00000186766 Forkhead box I2 10 127737235-127741186 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cervix, uterine: 2.6 kidney: 1.6 -SPIN4 FLJ44984, TDRD28 ENSG00000186767 Spindlin family, member 4 X 63347228-63351344 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044559 Uncertain Approved Nucleoli
Cytosol Mixed placenta: 6.3 -ZNF732 FLJ59067 ENSG00000186777 Zinc finger protein 732 4 270675-305321 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 2.7 breast: 0.8 -SPIN2B SPIN-2, TDRD26 ENSG00000186787 Spindlin family, member 2B X 57118551-57121547 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000162, HPA069835 Uncertain Approved Nucleoplasm Expressed in all cerebral cortex: 14.9 -SPATA31D3 FAM75D3, FLJ44082 ENSG00000186788 SPATA31 subfamily D, member 3 9 81943500-81995251 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 96 testis: 9.5 epididymis: 0.0 -FOXE3 FKHL12, FREAC8 ENSG00000186790 Forkhead box E3 1 47416072-47418052 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.6 -HYAL3 LUCA-3, LUCA14, Minna14 ENSG00000186792 Hyaluronoglucosaminidase 3 3 50292831-50299468 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049402 Uncertain Tissue enhanced 0 bone marrow: 22.7 testis: 14.1 -KCNK18 K2p18.1, TRESK, TRESK-2, TRESK2, TRIK ENSG00000186795 Potassium channel, two pore domain subfamily K, member 18 10 117197489-117210299 Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level No evidence Evidence at protein level HPA044739 Uncertain Not detected testis: 0.2 -IFNA10 IFN-alphaC ENSG00000186803 Interferon, alpha 10 9 21206181-21207143 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected epididymis: 0.0 -VSIG10L ENSG00000186806 V-set and immunoglobulin domain containing 10 like 19 51331536-51342124 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA060453, HPA066745 Uncertain Validated Nucleus Tissue enhanced 0 esophagus: 31.5;salivary gland: 9.3 tonsil: 6.0 -CXCR3 CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR ENSG00000186810 Chemokine (C-X-C motif) receptor 3 X 71615916-71618517 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045942 Supported Tissue enhanced 0 lymph node: 18.1 spleen: 8.9 -ZNF397 MGC13250, ZNF47, ZSCAN15 ENSG00000186812 Zinc finger protein 397 18 35241030-35267133 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026087 Uncertain Approved Nucleoli
Plasma membrane
Microtubules
Cytosol Expressed in all parathyroid gland: 32.8 -ZSCAN30 ZNF397OS, ZNF917 ENSG00000186814 Zinc finger and SCAN domain containing 30 18 35251058-35290245 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007289 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 27.1 -TPCN1 FLJ20612, KIAA1169, TPC1 ENSG00000186815 Two pore segment channel 1 12 113221050-113298585 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039757 Approved Expressed in all thyroid gland: 53.3 -LILRB4 CD85k, HM18, ILT3, LIR-5, LIR5 ENSG00000186818 Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 19 54643889-54670359 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052807 Approved Tissue enhanced 0 appendix: 15.1;lymph node: 13.6 urinary bladder: 8.5 -TNFRSF4 ACT35, CD134, OX40, TXGP1L ENSG00000186827 Tumor necrosis factor receptor superfamily, member 4 1 1211326-1214138 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB016128 Supported Tissue enhanced 0 adipose tissue: 9.7;appendix: 8.6 lymph node: 7.2 -KRT16 NEPPK ENSG00000186832 Keratin 16, type I 17 41609778-41615899 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000136, HPA000539 Approved Uncertain Intermediate filaments Group enriched 6 esophagus: 479.6;tonsil: 106.5 seminal vesicle: 52.4 -HEXIM1 CLP-1, EDG1, HIS1, MAQ1 ENSG00000186834 Hexamethylene bis-acetamide inducible 1 17 45148502-45152101 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008926, CAB011625 Supported Validated Nucleoplasm
Vesicles Expressed in all placenta: 36.5 -SELV ENSG00000186838 Selenoprotein V 19 39515113-39520686 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA059274 Uncertain Group enriched 13 parathyroid gland: 1.8;testis: 5.6;thyroid gland: 2.1 cerebral cortex: 0.2 -LCE1A LEP1 ENSG00000186844 Late cornified envelope 1A 1 152827473-152827894 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 10 skin: 506.0 breast: 49.7 -KRT14 EBS3, EBS4 ENSG00000186847 Keratin 14, type I 17 41582279-41586921 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000134, HPA000452, HPA000539, HPA023040 Supported Supported Intermediate filaments Tissue enriched 19 skin: 7966.8 breast: 417.5 -TRABD2A C2orf89, TIKI1 ENSG00000186854 TraB domain containing 2A 2 84821650-84907008 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045817 Approved Tissue enhanced 0 colon: 35.8;ovary: 30.5;rectum: 43.4 lymph node: 11.8 -KRTAP17-1 KAP17.1 ENSG00000186860 Keratin associated protein 17-1 17 41314917-41315695 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Not detected endometrium: 0.1 -PDZD7 bA108L7.8, FLJ23209, PDZK7 ENSG00000186862 PDZ domain containing 7 10 101007683-101031157 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 small intestine: 13.6 cerebral cortex: 9.0 -POFUT2 C21orf80, FUT13, KIAA0958 ENSG00000186866 Protein O-fucosyltransferase 2 21 45263928-45287898 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044297 Uncertain Expressed in all placenta: 24.2 -QRFPR GPR103 ENSG00000186867 Pyroglutamylated RFamide peptide receptor 4 121329312-121381059 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014300 Uncertain Not detected heart muscle: 0.6 -MAPT DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau ENSG00000186868 Microtubule-associated protein tau 17 45894382-46028334 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000151, HPA048895, HPA069524, HPA069570 Supported Supported Nuclear speckles
Plasma membrane Tissue enriched 8 cerebral cortex: 116.6 skeletal muscle: 13.7 -ERCC6L FLJ20105, PICH, RAD26L ENSG00000186871 Excision repair cross-complementation group 6-like X 72204657-72239047 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050492 Approved Supported Nucleoplasm
Centrosome
Cytosol Mixed lymph node: 2.8 -OR13F1 ENSG00000186881 Olfactory receptor, family 13, subfamily F, member 1 9 104504263-104505222 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -TMEM17 FLJ34583 ENSG00000186889 Transmembrane protein 17 2 62500221-62511894 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA018100 Uncertain Approved Actin filaments Mixed testis: 8.1 -TNFRSF18 AITR, CD357, GITR ENSG00000186891 Tumor necrosis factor receptor superfamily, member 18 1 1203508-1206691 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA008025 Approved Tissue enhanced 0 skin: 43.3 parathyroid gland: 17.6 -FGF3 HBGF-3, INT2 ENSG00000186895 Fibroblast growth factor 3 11 69810224-69819024 Cancer-related genes, Disease related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA012692 Uncertain Approved Not detected adipose tissue: 0.0 -C1QL4 C1QTNF11, CTRP11 ENSG00000186897 Complement component 1, q subcomponent-like 4 12 49332411-49337188 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 2.1;thyroid gland: 1.2 cerebral cortex: 0.7 -RTN4RL2 NgR2, NGRH1 ENSG00000186907 Reticulon 4 receptor-like 2 11 57460549-57477534 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 cerebral cortex: 48.9;thyroid gland: 36.1 liver: 6.6 -ZDHHC17 HIP14, HYPH, KIAA0946 ENSG00000186908 Zinc finger, DHHC-type containing 17 12 76763588-76853696 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016807 Approved Supported Golgi apparatus
Vesicles
Cytosol Expressed in all cerebral cortex: 45.4 -SERPINA11 ENSG00000186910 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 14 94442464-94452790 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 30 liver: 255.3 cervix: 8.6 -P2RY4 NRU, P2P, P2Y4, UNR ENSG00000186912 Pyrimidinergic receptor P2Y, G-protein coupled, 4 X 70258170-70259764 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB022644 Uncertain Tissue enhanced 0 small intestine: 3.1 rectum: 0.6 -ZNF395 DKFZp434K1210, HDBP2, PBF, PRF-1 ENSG00000186918 Zinc finger protein 395 8 28345585-28402701 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049382 Approved Nucleus
Cytosol Expressed in all ovary: 66.8 -ZACN L2, LGICZ, LGICZ1, ZAC, ZAC1 ENSG00000186919 Zinc activated ligand-gated ion channel 17 76071961-76083666 Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -KRTAP22-1 KAP22.1 ENSG00000186924 Keratin associated protein 22-1 21 30601087-30601382 Predicted intracellular proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -KRTAP19-6 KAP19.6 ENSG00000186925 Keratin associated protein 19-6 21 30541535-30541864 Predicted intracellular proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -KRTAP6-2 KAP6.2 ENSG00000186930 Keratin associated protein 6-2 21 30598590-30598902 Predicted intracellular proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -OR13C8 ENSG00000186943 Olfactory receptor, family 13, subfamily C, member 8 9 104569168-104570130 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence No evidence Evidence at protein level Not detected adipose tissue: 0.0 -PPARA hPPAR, NR1C1, PPAR ENSG00000186951 Peroxisome proliferator-activated receptor alpha 22 46150521-46243756 FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA058901, HPA067049 Supported Nucleus Expressed in all kidney: 24.0 -TMEM232 FLJ43080 ENSG00000186952 Transmembrane protein 232 5 110289233-110738956 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049386 Uncertain Tissue enhanced 0 fallopian tube: 26.1;testis: 35.3 thyroid gland: 7.3 -KRTAP19-2 KAP19.2 ENSG00000186965 Keratin associated protein 19-2 21 30487057-30487436 Predicted intracellular proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -KRTAP19-4 KAP19.4 ENSG00000186967 Keratin associated protein 19-4 21 30496824-30497133 Predicted intracellular proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -KRTAP15-1 KAP15.1 ENSG00000186970 Keratin associated protein 15-1 21 30440275-30440945 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -KRTAP13-4 KAP13.4 ENSG00000186971 Keratin associated protein 13-4 21 30430230-30431026 Predicted intracellular proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected parathyroid gland: 0.2 -FAM183A hCG23177, LOC440585 ENSG00000186973 Family with sequence similarity 183, member A 1 43145153-43156396 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA043382, HPA049120 Approved Tissue enriched 13 fallopian tube: 152.0 skin: 11.3 -EFCAB6 dJ185D5.1, DJBP, FLJ23588, HSCBCIP1, KIAA1672 ENSG00000186976 EF-hand calcium binding domain 6 22 43528744-43812337 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003098 Uncertain Nucleoplasm Group enriched 5 fallopian tube: 12.0;testis: 43.9 thyroid gland: 5.1 -KRTAP19-5 KAP19.5 ENSG00000186977 Keratin associated protein 19-5 21 30501657-30502117 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Not detected adipose tissue: 0.0 -KRTAP23-1 KAP23.1 ENSG00000186980 Keratin associated protein 23-1 21 30348399-30348609 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -KANK3 ANKRD47, FLJ46061 ENSG00000186994 KN motif and ankyrin repeat domains 3 19 8322584-8343262 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051153 Approved Approved Plasma membrane Tissue enhanced 0 spleen: 25.4 adipose tissue: 22.0 -EMID1 EMI5, EMU1, hEmu1 ENSG00000186998 EMI domain containing 1 22 29205851-29259597 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA000592 Uncertain Mixed spleen: 31.1 -ACTL7A ENSG00000187003 Actin-like 7A 9 108862266-108863759 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021624 Supported Tissue enriched 1933 testis: 193.2 adipose tissue: 0.0 -KRTAP21-1 KAP21.1 ENSG00000187005 Keratin associated protein 21-1 21 30754830-30755428 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Group enriched 7 breast: 13.5;testis: 5.9 seminal vesicle: 1.3 -RHD CD240D, DIIIc, RH, Rh30a, Rh4, RhII, RhPI ENSG00000187010 Rh blood group, D antigen 1 25272393-25330445 Blood group antigen proteins, CD markers, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 bone marrow: 9.2 skin: 2.5 -ESPN DFNB36 ENSG00000187017 Espin 1 6424788-6461370 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028674, HPA060220 Approved Approved Vesicles Tissue enhanced 0 skin: 90.1;testis: 110.4 small intestine: 47.5 -PNLIPRP1 PLRP1 ENSG00000187021 Pancreatic lipase-related protein 1 10 116590385-116609175 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 371 pancreas: 2294.5 ovary: 6.1 -PTRH1 C9orf115, PTH1 ENSG00000187024 Peptidyl-tRNA hydrolase 1 homolog 9 127692978-127724873 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021223 Uncertain Expressed in all adipose tissue: 11.1 -KRTAP21-2 KAP21.2 ENSG00000187026 Keratin associated protein 21-2 21 30746794-30747233 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Group enriched 20 skin: 1.1;testis: 2.9 epididymis: 0.0 -SAMD7 DKFZp686E1583 ENSG00000187033 Sterile alpha motif domain containing 7 3 169911572-169939175 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044187 Uncertain Not detected parathyroid gland: 0.5 -GPR141 PGR13 ENSG00000187037 G protein-coupled receptor 141 7 37683796-37833788 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 bone marrow: 18.7 appendix: 5.8 -TMPRSS6 FLJ30744 ENSG00000187045 Transmembrane protease, serine 6 22 37065436-37109563 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 6 liver: 40.7;testis: 8.7 stomach: 4.1 -CYP4A11 CYP4A2, CYP4AII ENSG00000187048 Cytochrome P450, family 4, subfamily A, polypeptide 11 1 46929177-46941484 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 175 kidney: 230.7;liver: 447.9 epididymis: 1.9 -TMEM216 CORS2, HSPC244, JBTS2, MGC13379, MKS2 ENSG00000187049 Transmembrane protein 216 11 61391687-61398863 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed ovary: 32.3 -RPS19BP1 FLJ21770, MGC52010 ENSG00000187051 Ribosomal protein S19 binding protein 1 22 39529093-39532855 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042874 Uncertain Supported Nucleus
Nucleoli
Cytosol Expressed in all adrenal gland: 57.5 -TMPRSS11A ECRG1 ENSG00000187054 Transmembrane protease, serine 11A 4 67909385-67964140 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 71 esophagus: 115.7;tonsil: 30.7 cervix: 1.0 -TMEM262 ENSG00000187066 Transmembrane protein 262 11 65084979-65089375 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 57 testis: 13.7 cervix: 0.2 -C3orf70 ENSG00000187068 Chromosome 3 open reading frame 70 3 185078050-185153014 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041861 Uncertain Approved Cytosol Tissue enhanced 0 smooth muscle: 25.7 cerebral cortex: 19.2 -TEAD1 AA, TCF13, TEF-1 ENSG00000187079 TEA domain family member 1 (SV40 transcriptional enhancer factor) 11 12674591-12944483 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057339, HPA062471 Validated Nucleus
Cytosol Mixed parathyroid gland: 84.8 -OR2AK2 OR2AK1P ENSG00000187080 Olfactory receptor, family 2, subfamily AK, member 2 1 247965233-247966339 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA052544 Uncertain Not detected testis: 0.2 -DEFB106B ENSG00000187082 Defensin, beta 106B 8 7482504-7486400 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045592 Supported Tissue enriched 17847 epididymis: 2055.2 esophagus: 0.1 -PLCD1 ENSG00000187091 Phospholipase C, delta 1 3 38007496-38029762 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009913, HPA020107, HPA021677 Approved Approved Microtubules Mixed testis: 38.3 -CCK ENSG00000187094 Cholecystokinin 3 42257825-42266207 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002308, HPA045039 Supported Supported Group enriched 5 cerebral cortex: 134.1;duodenum: 119.6;prostate: 32.8 small intestine: 18.1 -ENTPD5 CD39L4, NTPDase-5, PCPH ENSG00000187097 Ectonucleoside triphosphate diphosphohydrolase 5 14 73958010-74019399 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002927 Supported Approved Cytosol Tissue enhanced 0 liver: 130.1 rectum: 114.3 -MITF bHLHe32, MI, WS2, WS2A ENSG00000187098 Microphthalmia-associated transcription factor 3 69739435-69968337 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002578, HPA003259 Supported Tissue enhanced 0 cervix, uterine: 80.4;endometrium: 78.8 smooth muscle: 68.6 -HEATR4 MGC48595 ENSG00000187105 HEAT repeat containing 4 14 73478484-73558947 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 5 testis: 23.2 skin: 4.5 -NAP1L1 MGC23410, MGC8688, NAP1, NAP1L, NRP ENSG00000187109 Nucleosome assembly protein 1-like 1 12 76036587-76085033 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028861 Approved Uncertain Microtubules Expressed in all ovary: 740.7 -LILRA5 CD85, CD85f, ILT11, LILRB7, LIR9 ENSG00000187116 Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 19 54307070-54313139 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 14.2;bone marrow: 10.3;spleen: 7.4 urinary bladder: 2.4 -CMC1 C3orf68, MGC61571 ENSG00000187118 C-x(9)-C motif containing 1 3 28241584-28325142 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043333 Approved Expressed in all kidney: 33.3 -SLIT1 MEGF4, SLIL1, Slit-1, slit1, SLIT3 ENSG00000187122 Slit guidance ligand 1 10 96998038-97185920 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 14 cerebral cortex: 60.2 thyroid gland: 4.1 -LYPD6 MGC52057 ENSG00000187123 LY6/PLAUR domain containing 6 2 149329985-149474148 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042805 Uncertain Approved Cytosol Tissue enhanced 0 gallbladder: 17.3;placenta: 22.4 breast: 11.8 -AKR1C1 DD1, DDH, DDH1, HAKRC, MBAB ENSG00000187134 Aldo-keto reductase family 1, member C1 10 4963253-5107522 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB047303, HPA068265 Uncertain Supported Endoplasmic reticulum
Cytosol Expressed in all liver: 406.4 -VSTM2B ENSG00000187135 V-set and transmembrane domain containing 2B 19 29526499-29564479 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 20 cerebral cortex: 42.5 cervix: 2.0 -FOXD3 Genesis, HFH2 ENSG00000187140 Forkhead box D3 1 63323041-63325126 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022455 Uncertain Mixed testis: 1.0 -SPATA21 spergen-2, spergen2 ENSG00000187144 Spermatogenesis associated 21 1 16387117-16437424 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA032080 Approved Vesicles
Cytosol Tissue enriched 14 testis: 8.3 skin: 0.6 -RNF220 C1orf164, FLJ10597 ENSG00000187147 Ring finger protein 220 1 44405194-44651724 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027577, HPA027578 Uncertain Approved Nucleus Expressed in all cerebral cortex: 48.0 -ANGPTL5 ENSG00000187151 Angiopoietin-like 5 11 101890674-101916522 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA038516 Uncertain Tissue enhanced 0 ovary: 27.2 breast: 7.2 -SHTN1 KIAA1598, shootin-1, shootin1 ENSG00000187164 Shootin 1 10 116881482-117126586 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037942, HPA037943 Supported Approved Nucleus
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 36.2 parathyroid gland: 18.6 -H1FNT H1T2, HANP1 ENSG00000187166 H1 histone family, member N, testis-specific 12 48328980-48330279 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046204 Approved Tissue enriched 352 testis: 77.7 cerebral cortex: 0.2 -LCE4A LEP8, SPRL4A ENSG00000187170 Late cornified envelope 4A 1 152708160-152709491 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 6 skin: 5.1 breast: 0.8 -LCE2A LEP9 ENSG00000187173 Late cornified envelope 2A 1 152698364-152699442 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 13 skin: 146.5 breast: 11.3 -KRTAP12-1 KAP12.1, KRTAP12.1 ENSG00000187175 Keratin associated protein 12-1 21 44681576-44682163 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected parathyroid gland: 0.1 -LCE2C LEP11 ENSG00000187180 Late cornified envelope 2C 1 152675295-152676574 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 10 skin: 283.3 breast: 29.2 -RP11-195F19.5 ENSG00000187186 9 34664163-34666112 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA069617 Supported Approved Nucleoli
Endoplasmic reticulum
Vesicles Tissue enriched 5 testis: 139.6 cerebral cortex: 25.8 -ZNF546 MGC43537, ZNF49 ENSG00000187187 Zinc finger protein 546 19 39984134-40021041 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA030838 Approved Nucleus
Cytosol Tissue enhanced 0 testis: 14.4 parathyroid gland: 3.3 -TSPYL4 dJ486I3.2, KIAA0721 ENSG00000187189 TSPY-like 4 6 116249961-116254140 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044863 Approved Expressed in all cerebral cortex: 121.1 -DAZ3 ENSG00000187191 Deleted in azoospermia 3 Y 24763069-24813492 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047113 Approved Tissue enriched 11 testis: 1.0 adipose tissue: 0.0 -MT1X MT-1l, MT1 ENSG00000187193 Metallothionein 1X 16 56682424-56684196 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 1345.5 -GCNT1 C2GNT, NACGT2, NAGCT2 ENSG00000187210 Glucosaminyl (N-acetyl) transferase 1, core 2 9 76419850-76507416 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003522, HPA003523, HPA031151 Uncertain Supported Nuclear speckles Tissue enhanced 0 parathyroid gland: 183.3 duodenum: 51.5 -LCE2D LEP12, SPRL1A ENSG00000187223 Late cornified envelope 2D 1 152663396-152664659 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 14 skin: 136.2 breast: 9.8 -SESTD1 DKFZp434O0515, Solo ENSG00000187231 SEC14 and spectrin domains 1 2 179101692-179264790 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039578 Approved Microtubule organizing center
Cytosol Mixed testis: 16.9 -LCE3B LEP14 ENSG00000187238 Late cornified envelope 3B 1 152613811-152614098 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 30 tonsil: 2.9 epididymis: 0.0 -FNBP1 FBP17, KIAA0554 ENSG00000187239 Formin binding protein 1 9 129887187-130043194 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019691, HPA022119 Supported Expressed in all lymph node: 91.9 -DYNC2H1 DHC1b, DHC2, DNCH2, DYH1B, hdhc11 ENSG00000187240 Dynein, cytoplasmic 2, heavy chain 1 11 103109431-103479863 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039015, HPA039016 Approved Supported Mitochondria Mixed parathyroid gland: 17.1 -KRT12 K12 ENSG00000187242 Keratin 12, type I 17 40861303-40867210 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055217, HPA055835 Supported Not detected small intestine: 0.7 -MAGED4B ENSG00000187243 Melanoma antigen family D4B X 52061827-52069248 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA003554 Approved Tissue enhanced 0 cerebral cortex: 35.2 endometrium: 13.8 -BCAM CD239, LU ENSG00000187244 Basal cell adhesion molecule (Lutheran blood group) 19 44809059-44821420 Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005654 Uncertain Approved Nucleoli fibrillar center Expressed in all fallopian tube: 172.9 -RSBN1L FLJ42526, FLJ45813, MGC71764 ENSG00000187257 Round spermatid basic protein 1-like 7 77696443-77783022 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020406, HPA020413 Approved Supported Nuclear speckles
Plasma membrane Expressed in all testis: 47.0 -NPSR1 GPR154, GPRA, PGR14 ENSG00000187258 Neuropeptide S receptor 1 7 34658239-34878332 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA007489 Supported Not detected stomach: 0.5 -WDR86 ENSG00000187260 WD repeat domain 86 7 151375909-151410727 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA021086 Uncertain Tissue enhanced 0 parathyroid gland: 23.6;spleen: 14.6 fallopian tube: 7.5 -EPOR ENSG00000187266 Erythropoietin receptor 19 11377205-11384342 Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA077613 Uncertain Vesicles Tissue enhanced 0 parathyroid gland: 52.9 thyroid gland: 18.1 -FAM9C TEX39C ENSG00000187268 Family with sequence similarity 9, member C X 13035618-13044682 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 7 spleen: 55.1 testis: 8.2 -KRTAP9-8 KAP9.8 ENSG00000187272 Keratin associated protein 9-8 17 41232475-41239004 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected adipose tissue: 0.0 -CIDEC CIDE-3, FLJ20871, Fsp27 ENSG00000187288 Cell death-inducing DFFA-like effector c 3 9866711-9880254 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA018837, HPA020553 Approved Tissue enriched 8 adipose tissue: 760.1 small intestine: 101.3 -DCC IGDCC1, NTN1R1 ENSG00000187323 DCC netrin 1 receptor 18 52340172-53535903 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055376, HPA069552 Supported Approved Golgi apparatus Tissue enhanced 0 cerebral cortex: 3.7;testis: 13.4 lung: 2.2 -TAF9B DN-7, DN7, TAF9L, TAFII31L, TFIID-31 ENSG00000187325 TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa X 78129748-78139706 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045275, HPA058961 Approved Supported Nucleoplasm Expressed in all smooth muscle: 44.5 -PCDHB13 PCDH-BETA13 ENSG00000187372 Protocadherin beta 13 5 141213919-141218979 Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed endometrium: 2.5 -MAGI2 ACVRIP1, AIP1, ARIP1, KIAA0705, MAGI-2 ENSG00000187391 Membrane associated guanylate kinase, WW and PDZ domain containing 2 7 78017057-79453574 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013650 Approved Tissue enhanced 0 cerebral cortex: 44.0;parathyroid gland: 37.4 prostate: 13.0 -LUZP2 ENSG00000187398 Leucine zipper protein 2 11 24496970-25082631 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039007, HPA046161 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Group enriched 6 adrenal gland: 8.5;cerebral cortex: 33.1 prostate: 3.3 -LHFPL3 LHFPL4 ENSG00000187416 Lipoma HMGIC fusion partner-like 3 7 104328656-104907232 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA069691 Approved Vesicles Tissue enriched 11 cerebral cortex: 48.9 cervix: 4.6 -CHP1 CHP, p22, p24, Sid470p, SLC9A1BP ENSG00000187446 Calcineurin-like EF-hand protein 1 15 41230839-41281890 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006616 Approved Approved Vesicles Expressed in all colon: 113.0 -FPR3 FMLPY, FPRH1, FPRL2, RMLP-R-I ENSG00000187474 Formyl peptide receptor 3 19 51795163-51826189 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed lung: 41.3 -HIST1H1T H1FT, H1t ENSG00000187475 Histone cluster 1, H1t 6 26107419-26108136 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA065718, HPA068266 Supported Tissue enriched 7 testis: 1.4 prostate: 0.1 -C11orf96 AG2 ENSG00000187479 Chromosome 11 open reading frame 96 11 43925342-43944338 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038843 Uncertain Approved Nucleus
Focal adhesion sites
Cytosol Tissue enhanced 0 adrenal gland: 164.1 adipose tissue: 126.9 -KCNJ11 BIR, Kir6.2 ENSG00000187486 Potassium channel, inwardly rectifying subfamily J, member 11 11 17385859-17389331 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA048891 Approved Tissue enhanced 0 skeletal muscle: 32.7 cerebral cortex: 10.2 -CDHR4 CDH29, VLLR9392 ENSG00000187492 Cadherin-related family member 4 3 49790732-49799835 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 9 fallopian tube: 103.8 lung: 11.5 -COL4A1 ENSG00000187498 Collagen, type IV, alpha 1 13 110148963-110307149 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB001695, HPA054039 Approved Uncertain Nucleoplasm
Cytosol Tissue enhanced 0 placenta: 1227.8 smooth muscle: 431.0 -PLEKHG7 FLJ46688 ENSG00000187510 Pleckstrin homology domain containing, family G (with RhoGef domain) member 7 12 92721505-92772455 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060632 Uncertain Tissue enhanced 0 fallopian tube: 6.1 epididymis: 4.2 -GJA4 CX37 ENSG00000187513 Gap junction protein, alpha 4, 37kDa 1 34792998-34795747 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA047981 Approved Tissue enhanced 0 placenta: 88.6 fallopian tube: 47.8 -PTMA TMSA ENSG00000187514 Prothymosin, alpha 2 231706895-231713541 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047183, HPA052651 Approved Validated Nucleus
Cytosol Expressed in all lymph node: 1641.4 -HYPM CXorf27, HIP17 ENSG00000187516 Huntingtin interacting protein M X 37990817-37991317 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA003356 Uncertain Tissue enriched 152 testis: 49.7 skin: 0.3 -HSPA14 HSP70-4, HSP70L1 ENSG00000187522 Heat shock 70kDa protein 14 10 14838164-14871741 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046180 Approved Expressed in all testis: 65.2 -ATP13A5 FLJ16025 ENSG00000187527 ATPase type 13A5 3 193274790-193378843 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA031771, HPA031774 Uncertain Tissue enhanced 0 breast: 17.8 salivary gland: 4.0 -SIRT7 ENSG00000187531 Sirtuin 7 17 81911939-81921323 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037261, HPA053669 Supported Supported Nucleoli fibrillar center
Vesicles Mixed esophagus: 21.7 -PRR27 C4orf40 ENSG00000187533 Proline rich 27 4 70133616-70176799 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036150, HPA036151 Supported Tissue enriched 1046 salivary gland: 405.2 ovary: 0.3 -IFT140 gs114, KIAA0590, WDTC2 ENSG00000187535 Intraflagellar transport 140 16 1510427-1612110 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042197 Approved Mixed fallopian tube: 23.8 -POTEG A26C2, CT104.4, POTE-14, POTE14, POTE14alpha ENSG00000187537 POTE ankyrin domain family, member G 14 19402486-19434341 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042822 Uncertain Tissue enhanced 0 prostate: 3.3 testis: 0.7 -PRAMEF10 ENSG00000187545 PRAME family member 10 1 12892896-12898270 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12 liver: 1.1 adipose tissue: 0.0 -AGMO FLJ16237, TMEM195 ENSG00000187546 Alkylglycerol monooxygenase 7 15200318-15562015 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA057900 Uncertain Vesicles Tissue enhanced 0 liver: 63.6 epididymis: 17.5 -SBK2 SGK069 ENSG00000187550 SH3 domain binding kinase family, member 2 19 55529733-55537089 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA030631 Uncertain Tissue enriched 33 heart muscle: 26.5 testis: 0.8 -CYP26C1 ENSG00000187553 Cytochrome P450, family 26, subfamily C, polypeptide 1 10 93060808-93069536 Disease related genes, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected spleen: 0.2 -TLR5 FLJ10052, MGC126430, MGC126431, SLEB1, TIL3 ENSG00000187554 Toll-like receptor 5 1 223109406-223143282 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009013 Approved Nucleus
Golgi apparatus
Cytosol Mixed ovary: 25.1 -USP7 HAUSP ENSG00000187555 Ubiquitin specific peptidase 7 (herpes virus-associated) 16 8892094-8964514 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008108, HPA015641 Approved Expressed in all testis: 108.6 -NANOS3 NANOS1L, NOS3 ENSG00000187556 Nanos homolog 3 (Drosophila) 19 13862063-13880757 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062989 Uncertain Tissue enriched 6 testis: 7.0 cerebral cortex: 1.2 -FOXD4L3 FOXD6 ENSG00000187559 Forkhead box D4-like 3 9 68302867-68304905 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA012836 Uncertain Approved Nucleus Not detected spleen: 0.3 -NHLRC1 bA204B7.2, EPM2B, malin ENSG00000187566 NHL repeat containing E3 ubiquitin protein ligase 1 6 18121419-18122606 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA066030 Uncertain Vesicles Mixed skin: 4.6 -DPPA3 Stella ENSG00000187569 Developmental pluripotency associated 3 12 7711454-7717559 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 1.4 lung: 0.6 -COX8C COX8-3 ENSG00000187581 Cytochrome c oxidase subunit VIIIC 14 93347191-93348356 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003127 Approved Tissue enriched 52 testis: 29.6 fallopian tube: 0.5 -PLEKHN1 DKFZP434H2010 ENSG00000187583 Pleckstrin homology domain containing, family N member 1 1 966497-975865 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031742 Uncertain Approved Nuclear speckles Group enriched 11 esophagus: 17.0;skin: 44.0 urinary bladder: 2.8 -ZNF385C ENSG00000187595 Zinc finger protein 385C 17 42025576-42065365 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 9.1 ovary: 2.0 -TMEM247 ENSG00000187600 Transmembrane protein 247 2 46429190-46484425 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enriched 27 testis: 35.8 placenta: 1.3 -MAGEH1 APR1 ENSG00000187601 Melanoma antigen family H1 X 55452105-55453566 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA011324 Uncertain Approved Nucleoli Tissue enriched 5 epididymis: 607.0 cerebral cortex: 116.1 -TET3 hCG_40738, MGC22014 ENSG00000187605 Tet methylcytosine dioxygenase 3 2 73986404-74108176 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA050845 Approved Approved Nucleoplasm
Vesicles
Cytosol Mixed skin: 18.0 -ZNF286A KIAA1874, ZNF286 ENSG00000187607 Zinc finger protein 286A 17 15699577-15720787 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA021594 Approved Nucleoli Mixed ovary: 21.8 -ISG15 G1P2, IFI15, UCRP ENSG00000187608 ISG15 ubiquitin-like modifier 1 1001138-1014541 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004627 Approved Expressed in all salivary gland: 113.1 -EXD3 FLJ20433, LOC54932, mut-7 ENSG00000187609 Exonuclease 3'-5' domain containing 3 9 137306896-137423262 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047395 Approved Approved Actin filaments
Focal adhesion sites Mixed spleen: 10.2 -OR5W2 OR5W2P, OR5W3P ENSG00000187612 Olfactory receptor, family 5, subfamily W, member 2 11 55913650-55914582 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -TMEM8C TMEM226 ENSG00000187616 Transmembrane protein 8C 9 133514586-133528612 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA051846, HPA055785 Uncertain Not detected epididymis: 0.5 -C17orf97 LOC400566 ENSG00000187624 Chromosome 17 open reading frame 97 17 410327-431062 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023583 Approved Approved Nucleoli
Cytosol Tissue enhanced 0 testis: 56.7 fallopian tube: 21.4 -ZKSCAN4 FLJ32136, P1P373C6, p373c6.1, ZNF307, ZNF427, ZSCAN36 ENSG00000187626 Zinc finger with KRAB and SCAN domains 4 6 28244623-28252224 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009637 Approved Supported Nucleoplasm Mixed testis: 18.2 -RGPD1 RGP1 ENSG00000187627 RANBP2-like and GRIP domain containing 1 2 86907953-87013981 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049497, HPA051675, HPA067564 Uncertain Approved Nuclear membrane
Vesicles Group enriched 8 cervix, uterine: 12.6;placenta: 14.2;testis: 44.0 bone marrow: 2.8 -DHRS4L2 SDR25C3 ENSG00000187630 Dehydrogenase/reductase (SDR family) member 4 like 2 14 23969874-24006408 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA023972 Uncertain Uncertain Nuclear membrane
Vesicles Expressed in all kidney: 121.8 -SAMD11 MGC45873 ENSG00000187634 Sterile alpha motif domain containing 11 1 924880-944581 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030110 Approved Nucleoplasm
Vesicles Tissue enhanced 0 seminal vesicle: 37.6 fallopian tube: 29.0 -PERM1 C1orf170, MGC13275, Perm1, RP11-54O7.8 ENSG00000187642 PPARGC1 and ESRR induced regulator, muscle 1 1 975204-982093 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031711, HPA031712 Supported Group enriched 15 heart muscle: 20.6;skeletal muscle: 68.1 esophagus: 3.0 -VMAC ENSG00000187650 Vimentin-type intermediate filament associated coiled-coil protein 19 5904858-5910853 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed spleen: 7.8 -C5orf52 ENSG00000187658 Chromosome 5 open reading frame 52 5 157671553-157680143 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 20 testis: 38.6 colon: 1.9 -HAPLN4 BRAL2, KIAA1926 ENSG00000187664 Hyaluronan and proteoglycan link protein 4 19 19255641-19262796 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055856 Approved Group enriched 7 cerebral cortex: 8.5;duodenum: 15.7;small intestine: 21.7 cervix: 2.1 -ERC2 CAST, CAST1, ELKSL, KIAA0378, SPBC110, Spc110 ENSG00000187672 ELKS/RAB6-interacting/CAST family member 2 3 55508308-56468363 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 16 cerebral cortex: 24.6 seminal vesicle: 1.4 -B3GLCT B3GALTL, B3Glc-T, B3GTL ENSG00000187676 Beta 3-glucosyltransferase 13 31199936-31332276 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017664 Approved Mixed endometrium: 20.9 -SPRY4 ENSG00000187678 Sprouty RTK signaling antagonist 4 5 142310427-142326455 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008086, HPA055471 Approved Supported Golgi apparatus
Cytosol Mixed adipose tissue: 26.7 -ERAS HRAS2, HRASP ENSG00000187682 ES cell expressed Ras X 48828873-48830138 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected cerebral cortex: 0.4 -TRPV2 VRL, VRL-1, VRL1 ENSG00000187688 Transient receptor potential cation channel, subfamily V, member 2 17 16415542-16437003 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044993 Uncertain Supported Plasma membrane Mixed lung: 44.1 -AMTN RSTI689, UNQ689 ENSG00000187689 Amelotin 4 70518540-70532742 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA036136, HPA036137 Uncertain Tissue enhanced 0 stomach: 7.0;tonsil: 25.8 prostate: 3.3 -CXorf67 ENSG00000187690 Chromosome X open reading frame 67 X 51406915-51408843 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA004003, HPA006128 Supported Validated Nucleoplasm Group enriched 20 placenta: 1.3;testis: 4.7 spleen: 0.1 -RP11-723O4.6 ENSG00000187695 Uncharacterized protein FLJ43738 3 128909874-128971330 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048390 Uncertain Tissue enhanced 0 fallopian tube: 7.6;testis: 11.9 skin: 2.4 -C2orf88 MGC13057, smAKAP ENSG00000187699 Chromosome 2 open reading frame 88 2 189879609-190203484 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049549 Approved Expressed in all testis: 92.3 -OR2T27 ENSG00000187701 Olfactory receptor, family 2, subfamily T, member 27 1 248649931-248650884 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -TMEM203 HBEBP1, MGC14327 ENSG00000187713 Transmembrane protein 203 9 137204082-137205638 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all cerebral cortex: 39.9 -SLC18A3 VACHT ENSG00000187714 Solute carrier family 18 (vesicular acetylcholine transporter), member 3 10 49610301-49612720 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB037102 Uncertain Not detected placenta: 0.6 -KBTBD12 FLJ46299, KLHDC6 ENSG00000187715 Kelch repeat and BTB (POZ) domain containing 12 3 127915232-127987671 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 9 heart muscle: 8.0;skeletal muscle: 20.3 fallopian tube: 1.5 -THSD4 ADAMTSL6, FLJ13710, FVSY9334, PRO34005 ENSG00000187720 Thrombospondin, type I, domain containing 4 15 71096952-71783383 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA026845 Approved Nucleus
Nucleoli Tissue enhanced 0 cervix, uterine: 159.1 fallopian tube: 58.5 -DNAJB13 RSPH16A, TSARG6 ENSG00000187726 DnaJ (Hsp40) homolog, subfamily B, member 13 11 73950319-73970366 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052465 Approved Group enriched 7 fallopian tube: 75.7;testis: 19.0 cervix: 6.5 -GABRD ENSG00000187730 Gamma-aminobutyric acid (GABA) A receptor, delta 1 2019324-2030751 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044371 Supported Uncertain Golgi apparatus
Vesicles Tissue enriched 10 cerebral cortex: 47.4 testis: 4.5 -AMY1C AMY1 ENSG00000187733 Amylase, alpha 1C (salivary) 1 103750406-103758690 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045394, HPA045399, HPA046980 Supported Tissue enhanced 0 cervix, uterine: 32.6;salivary gland: 102.5 pancreas: 26.4 -TCEA1 GTF2S, SII, TCEA, TF2S, TFIIS ENSG00000187735 Transcription elongation factor A (SII), 1 8 53966552-54022529 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043786 Approved Supported Nucleus
Nucleoli Expressed in all thyroid gland: 199.1 -NHEJ1 Cernunnos, FLJ12610, XLF ENSG00000187736 Nonhomologous end-joining factor 1 2 219075317-219160865 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012334, HPA043869 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all testis: 43.8 -FANCA FA-H, FAA, FACA, FAH, FANCH ENSG00000187741 Fanconi anemia, complementation group A 16 89737549-89816657 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063236 Supported Nucleus Mixed testis: 19.5 -SECISBP2 ENSG00000187742 SECIS binding protein 2 9 89318506-89359662 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044314, HPA054905 Approved Supported Nucleoplasm Expressed in all testis: 127.2 -OR52B6 ENSG00000187747 Olfactory receptor, family 52, subfamily B, member 6 11 5580877-5581884 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -C9orf153 bA507D14.1 ENSG00000187753 Chromosome 9 open reading frame 153 9 86220265-86259657 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 29 testis: 53.0 bone marrow: 1.8 -SSX7 ENSG00000187754 Synovial sarcoma, X breakpoint 7 X 52644090-52654900 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045683 Uncertain Not detected epididymis: 0.7 -ADH1A ADH1 ENSG00000187758 Alcohol dehydrogenase 1A (class I), alpha polypeptide 4 99276367-99291028 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009562, HPA047814, HPA060902 Supported Approved Plasma membrane
Cytosol Tissue enriched 134 liver: 1364.4 gallbladder: 10.2 -SEMA4D C9orf164, CD100, coll-4, FLJ39737, SEMAJ ENSG00000187764 Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 9 89360787-89498130 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015662, HPA023277 Approved Supported Endoplasmic reticulum
Vesicles Expressed in all lymph node: 73.3 -KRTAP10-8 KAP10.8, KRTAP18-8, KRTAP18.8 ENSG00000187766 Keratin associated protein 10-8 21 44612079-44612954 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -LIN28B CSDD2, FLJ16517 ENSG00000187772 Lin-28 homolog B (C. elegans) 6 104957048-105083332 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036630, HPA061745 Supported Supported Nucleus
Nucleoli
Cytosol Tissue enriched 13 placenta: 67.2 testis: 5.3 -FAM69C C18orf51 ENSG00000187773 Family with sequence similarity 69, member C 18 74434099-74457944 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA048928 Supported Tissue enhanced 0 cerebral cortex: 28.9;testis: 8.4 skin: 4.9 -DNAH17 DNAHL1, DNEL2, FLJ40457 ENSG00000187775 Dynein, axonemal, heavy chain 17 17 78423697-78577394 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 21 testis: 10.3 skin: 0.4 -MCRS1 ICP22BP, INO80Q, MCRS2, MSP58, P78 ENSG00000187778 Microspherule protein 1 12 49556544-49568153 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039057 Supported Supported Nucleoplasm Expressed in all thyroid gland: 54.9 -TMEM72 bA285G1.3, C10orf127, KSP37 ENSG00000187783 Transmembrane protein 72 10 44911200-44937002 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039894, HPA062907 Supported Tissue enriched 7 kidney: 54.0 rectum: 8.0 -FANCM FAAP250, KIAA1596 ENSG00000187790 Fanconi anemia, complementation group M 14 45135940-45200890 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055144 Supported Nucleoplasm Tissue enhanced 0 testis: 14.0 endometrium: 4.2 -FAM205C FAM205CP ENSG00000187791 Family with sequence similarity 205, member C 9 34889064-34895778 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 74 testis: 58.4 kidney: 0.7 -ZNF70 Cos17, MGC48959 ENSG00000187792 Zinc finger protein 70 22 23738678-23751092 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA018821 Uncertain Supported Cytosol Mixed ovary: 4.9 -CARD9 ENSG00000187796 Caspase recruitment domain family, member 9 9 136361903-136373681 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA059502 Approved Tissue enhanced 0 bone marrow: 7.1;spleen: 8.3 appendix: 5.9 -PEAR1 FLJ00193, JEDI, MEGF12 ENSG00000187800 Platelet endothelial aggregation receptor 1 1 156893698-156916434 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035217 Approved Approved Nucleoplasm
Cell Junctions
Centrosome Mixed placenta: 16.8 -ZFP69B FLJ34293, ZKSCAN23B, ZNF643, ZSCAN54B ENSG00000187801 ZFP69 zinc finger protein B 1 40450102-40463718 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA044289 Uncertain Approved Nucleus
Cytosol Mixed cerebral cortex: 3.7 -TMEM202 FLJ27523 ENSG00000187806 Transmembrane protein 202 15 72398273-72408029 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 241 testis: 24.1 adipose tissue: 0.0 -SOWAHD ANKRD58 ENSG00000187808 Sosondowah ankyrin repeat domain family member D X 119758613-119760164 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA065955 Uncertain Tissue enhanced 0 spleen: 5.2 testis: 3.6 -ZFP69 FLJ16030, ZFP69A, ZKSCAN23A, ZNF642, ZSCAN54A ENSG00000187815 ZFP69 zinc finger protein 1 40477215-40496343 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA027808, HPA054942 Uncertain Approved Nucleus Mixed testis: 6.8 -HELT bHLHb44, HCM1228, HESL, MEGANE, Mgn ENSG00000187821 Helt bHLH transcription factor 4 185018841-185020804 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA036188, HPA036189 Uncertain Not detected lung: 0.5 -ZCCHC16 FLJ46608, Mar4, Mart4 ENSG00000187823 Zinc finger, CCHC domain containing 16 X 112454500-112457112 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA003272 Uncertain Approved Nucleus
Plasma membrane
Cytosol Not detected kidney: 0.8 -TMEM220 ENSG00000187824 Transmembrane protein 220 17 10699015-10730316 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Expressed in all liver: 53.9 -C2orf78 COG5373, FLJ43987, hCG1989538 ENSG00000187833 Chromosome 2 open reading frame 78 2 73784189-73817147 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 147 testis: 14.7 adipose tissue: 0.0 -HIST1H1C H1.2, H1c, H1F2, H1s-1 ENSG00000187837 Histone cluster 1, H1c 6 26055787-26056428 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011507, HPA055907 Supported Supported Nucleus
Nucleoli Expressed in all bone marrow: 185.5 -TMEM256-PLSCR3 ENSG00000187838 TMEM256-PLSCR3 readthrough (NMD candidate) 17 7389727-7394843 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048387, HPA068609 Supported Supported Mitochondria Expressed in all smooth muscle: 38.5 -EIF4EBP1 4E-BP1, PHAS-I ENSG00000187840 Eukaryotic translation initiation factor 4E binding protein 1 8 38030341-38060365 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005032, CAB005039, HPA023501 Supported Supported Nucleoplasm
Cytosol Expressed in all adipose tissue: 30.4 -P2RX2 DFNA41, P2X2 ENSG00000187848 Purinergic receptor P2X, ligand gated ion channel, 2 12 132618780-132622386 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 epididymis: 26.2;seminal vesicle: 12.6 prostate: 9.0 -ASCL4 bHLHa44, HASH4 ENSG00000187855 Achaete-scute family bHLH transcription factor 4 12 107774385-107776644 Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level HPA036116 Uncertain Not detected parathyroid gland: 0.7 -OR6C75 ENSG00000187857 Olfactory receptor, family 6, subfamily C, member 75 12 55365111-55366049 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -CCDC157 ENSG00000187860 Coiled-coil domain containing 157 22 30356635-30378658 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042943 Uncertain Group enriched 5 fallopian tube: 11.8;testis: 28.5 thyroid gland: 3.9 -TTC24 ENSG00000187862 Tetratricopeptide repeat domain 24 1 156579727-156586770 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA029797, HPA029798, HPA029799 Uncertain Tissue enhanced 0 lymph node: 6.5;spleen: 3.9;tonsil: 4.4 appendix: 2.5 -FAM122A C9orf42, MGC17347 ENSG00000187866 Family with sequence similarity 122A 9 68780055-68784608 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056646 Approved Approved Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 21.0 -PALM3 ENSG00000187867 Paralemmin 3 19 14053365-14059159 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052794, HPA056119 Approved Approved Nucleoplasm
Nuclear bodies
Plasma membrane Mixed kidney: 15.8 -GFRAL bA360D14.1, C6orf144, GRAL, UNQ9356 ENSG00000187871 GDNF family receptor alpha like 6 55327469-55402493 Predicted membrane proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level HPA047372 Uncertain Not detected testis: 0.2 -C1orf168 FLJ43208, RP4-758N20.2 ENSG00000187889 Chromosome 1 open reading frame 168 1 56718804-56819696 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 fallopian tube: 21.2;liver: 8.6 cervix: 5.0 -SHISA7 ENSG00000187902 Shisa family member 7 19 55428740-55442863 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA058935 Uncertain Tissue enriched 11 cerebral cortex: 18.3 testis: 1.7 -LRRC74B ENSG00000187905 Leucine rich repeat containing 74B 22 21045960-21064168 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049947 Uncertain Group enriched 5 fallopian tube: 6.0;testis: 1.8 lung: 0.7 -DMBT1 GP340, muclin ENSG00000187908 Deleted in malignant brain tumors 1 10 122560665-122643736 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040778 Supported Tissue enhanced 0 duodenum: 876.2;small intestine: 299.5 salivary gland: 145.2 -CLEC17A FLJ45910 ENSG00000187912 C-type lectin domain family 17, member A 19 14583084-14611157 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 10 appendix: 17.3;lymph node: 30.8;spleen: 19.8;tonsil: 29.7 urinary bladder: 2.4 -OR51I2 ENSG00000187918 Olfactory receptor, family 51, subfamily I, member 2 11 5453489-5454427 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.1 -LCN10 ENSG00000187922 Lipocalin 10 9 136738167-136743356 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055919 Approved Tissue enriched 6 epididymis: 18.6 endometrium: 3.3 -LDLRAD2 ENSG00000187942 Low density lipoprotein receptor class A domain containing 2 1 21812265-21825221 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030478 Approved Mixed adipose tissue: 2.8 -C2orf66 UNQ6411 ENSG00000187944 Chromosome 2 open reading frame 66 2 196805002-196810276 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA020869 Uncertain Tissue enhanced 0 adipose tissue: 2.8;adrenal gland: 1.7;testis: 1.7 skin: 1.1 -OVCH1 OVCH ENSG00000187950 Ovochymase 1 12 29412474-29497686 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040253 Uncertain Group enriched 5 lung: 6.9;testis: 5.2;thyroid gland: 1.7 spleen: 0.8 -ARHGAP11B B'-T, FAM7B1 ENSG00000187951 Rho GTPase activating protein 11B 15 30624494-30772993 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA064479 Uncertain Approved Vesicles Tissue enhanced 0 bone marrow: 2.0 lymph node: 1.1 -CYHR1 CHRP, KIAA0496, MGC13010 ENSG00000187954 Cysteine/histidine-rich 1 8 144449582-144465677 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053653, HPA059543 Approved Validated Nucleoplasm Expressed in all testis: 51.5 -COL14A1 UND ENSG00000187955 Collagen, type XIV, alpha 1 8 120059780-120372036 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023781 Uncertain Approved Vesicles Tissue enhanced 0 cervix, uterine: 277.0 gallbladder: 208.3 -DNER bet, UNQ26 ENSG00000187957 Delta/notch-like EGF repeat containing 2 229357629-229714558 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017320 Approved Group enriched 7 adrenal gland: 74.9;cerebral cortex: 176.5 salivary gland: 17.4 -CPSF4L ENSG00000187959 Cleavage and polyadenylation specific factor 4-like 17 73248449-73262352 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044047 Uncertain Tissue enhanced 0 testis: 1.0 breast: 0.5 -KLHL17 ENSG00000187961 Kelch-like family member 17 1 960587-965715 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA031251 Approved Approved Nucleoplasm
Nuclear bodies Mixed skin: 9.7 -ZCCHC13 4930513O09RIK, Cnbp2, ZNF9L ENSG00000187969 Zinc finger, CCHC domain containing 13 X 74304190-74305031 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA003382 Supported Tissue enriched 233 testis: 23.2 epididymis: 0.0 -PLA2G2C ENSG00000187980 Phospholipase A2, group IIC 1 20161253-20177424 Predicted secreted proteins, RAS pathway related proteins Evidence at transcript level Evidence at transcript level No evidence Mixed esophagus: 1.2 -ZSCAN23 dJ29K1.3.1, ZNF390, ZNF453 ENSG00000187987 Zinc finger and SCAN domain containing 23 6 28431930-28443502 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035959, HPA035960 Uncertain Mixed parathyroid gland: 2.1 -RINL FLJ45909 ENSG00000187994 Ras and Rab interactor-like 19 38867834-38878279 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042083, HPA042103 Uncertain Approved Nucleoplasm
Vesicles Mixed lymph node: 14.2 -C17orf99 GLPG464, UNQ464 ENSG00000187997 Chromosome 17 open reading frame 99 17 78146353-78166177 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029655 Uncertain Approved Cytosol Tissue enriched 6 bone marrow: 5.5 lymph node: 0.9 -OR7D2 FLJ38149, HTPCRH03, OR19-4 ENSG00000188000 Olfactory receptor, family 7, subfamily D, member 2 19 9185594-9188817 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed testis: 2.0 -TPRG1 FAM79B, FLJ41238, FLJ43694 ENSG00000188001 Tumor protein p63 regulated 1 3 188947214-189325304 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044751, HPA060187 Uncertain Supported Nucleoplasm Tissue enhanced 0 esophagus: 49.2 breast: 29.2 -C1orf204 FLJ39187 ENSG00000188004 Chromosome 1 open reading frame 204 1 159834474-159855347 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA045602, HPA051028 Approved Uncertain Nucleoplasm Mixed ovary: 8.1 -MORN2 MOPT ENSG00000188010 MORN repeat containing 2 2 38875962-38929072 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA057815 Uncertain Approved Nucleoplasm Expressed in all testis: 264.0 -RTP5 C2orf85, CXXC11, FLJ33590, Z3CXXC5 ENSG00000188011 Receptor (chemosensory) transporter protein 5 (putative) 2 241869600-241873823 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA050902 Uncertain Tissue enriched 9 cerebral cortex: 5.3 lymph node: 0.5 -S100A3 S100E ENSG00000188015 S100 calcium binding protein A3 1 153547329-153549372 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042674, HPA056140 Approved Validated Nucleoli
Cytosol Tissue enhanced 0 lung: 20.2;skin: 17.3 cervix: 8.0 -UBQLN2 Chap1, CHAP1/DSK2, Dsk2, LIC-2, N4BP4, PLIC-2, PLIC2, RIHFB2157 ENSG00000188021 Ubiquilin 2 X 56563639-56567868 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006431, CAB013481 Supported Validated Plasma membrane
Cytosol Expressed in all cerebral cortex: 53.9 -RILPL1 FLJ39378 ENSG00000188026 Rab interacting lysosomal protein-like 1 12 123470054-123533718 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041314 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Mixed heart muscle: 43.9 -C19orf67 ENSG00000188032 Chromosome 19 open reading frame 67 19 14081619-14085875 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 11 testis: 5.6 thyroid gland: 0.5 -ZNF490 KIAA1198 ENSG00000188033 Zinc finger protein 490 19 12577961-12640098 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA005576 Uncertain Mixed thyroid gland: 2.8 -CLCN1 ClC-1, CLC1 ENSG00000188037 Chloride channel, voltage-sensitive 1 7 143316126-143352083 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 17 skeletal muscle: 22.9 testis: 1.3 -NRN1L MRCC2446, UNQ2446 ENSG00000188038 Neuritin 1-like 16 67884805-67888855 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041761 Uncertain Mixed skin: 3.3 -NWD1 ENSG00000188039 NACHT and WD repeat domain containing 1 19 16719976-16817963 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 7 cerebral cortex: 1.9;fallopian tube: 7.6;prostate: 5.8;seminal vesicle: 1.6 lung: 0.6 -ARL4C ARL7, LAK ENSG00000188042 ADP-ribosylation factor-like 4C 2 234493041-234497053 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028927 Uncertain Supported Plasma membrane
Cytosol Mixed spleen: 73.2 -RNF133 ENSG00000188050 Ring finger protein 133 7 122697712-122699156 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 182 testis: 60.5 lung: 0.3 -TMEM221 ENSG00000188051 Transmembrane protein 221 19 17435509-17448567 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA041580 Approved Uncertain Nuclear membrane Tissue enhanced 0 parathyroid gland: 7.0 fallopian tube: 4.4 -TREML4 TLT4 ENSG00000188056 Triggering receptor expressed on myeloid cells-like 4 6 41228324-41238882 Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA065044 Uncertain Not detected spleen: 0.5 -RAB42 MGC45806 ENSG00000188060 RAB42, member RAS oncogene family 1 28592200-28595443 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA050290 Approved Endoplasmic reticulum Mixed lymph node: 7.2 -WNT7B ENSG00000188064 Wingless-type MMTV integration site family, member 7B 22 45920362-45977129 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 21.4 urinary bladder: 8.2 -OR51F1 OR51F1P ENSG00000188069 Olfactory receptor, family 51, subfamily F, member 1 (gene/pseudogene) 11 4768979-4769917 Predicted membrane proteins No evidence No evidence Not detected epididymis: 0.0 -C11orf95 MGC3032 ENSG00000188070 Chromosome 11 open reading frame 95 11 63759892-63768775 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045002 Approved Intermediate filaments Expressed in all endometrium: 24.5 -SCGB1C1 RYD5 ENSG00000188076 Secretoglobin, family 1C, member 1 11 193080-194573 Predicted secreted proteins No evidence No evidence No evidence Not detected testis: 0.5 -PRSS45 TESSP5 ENSG00000188086 Protease, serine, 45 3 46742092-46812558 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060284 Uncertain Tissue enhanced 0 epididymis: 4.1 parathyroid gland: 1.5 -PLA2G4E FLJ45651 ENSG00000188089 Phospholipase A2, group IVE 15 41981582-42051190 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA041105 Supported Tissue enriched 10 skin: 20.4 tonsil: 2.0 -GPR89B GPR89, GPR89C, SH120 ENSG00000188092 G protein-coupled receptor 89B 1 147928393-147993521 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA076096 Approved Endoplasmic reticulum Expressed in all kidney: 30.9 -MESP2 bHLHc6, SCDO2 ENSG00000188095 Mesoderm posterior bHLH transcription factor 2 15 89760591-89778754 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed cervix: 1.1 -FAM25A bA96C23.5 ENSG00000188100 Family with sequence similarity 25, member A 10 87020306-87024730 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA044808 Uncertain Tissue enhanced 0 esophagus: 315.8;skin: 125.6 tonsil: 57.1 -EYS bA166P24.2, bA307F22.3, bA74E24.1, C6orf178, C6orf179, C6orf180, dJ1018A4.2, dJ303F19.1, EGFL10, EGFL11, RP25, SPAM ENSG00000188107 Eyes shut homolog (Drosophila) 6 63719980-65707225 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027103 Supported Mixed testis: 1.4 -C6orf132 bA7K24.2 ENSG00000188112 Chromosome 6 open reading frame 132 6 42101118-42142619 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044588 Supported Approved Golgi apparatus
Cytosol Tissue enhanced 0 esophagus: 81.2 skin: 50.1 -DAZ1 DAZ, SPGY ENSG00000188120 Deleted in azoospermia 1 Y 23129355-23199094 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA047113 Supported Tissue enhanced 0 testis: 1.8 stomach: 0.8 -OR2AG2 OR2AG2P ENSG00000188124 Olfactory receptor, family 2, subfamily AG, member 2 11 6767987-6769055 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.3 -MAPK12 ERK6, p38gamma, PRKM12, SAPK-3, SAPK3 ENSG00000188130 Mitogen-activated protein kinase 12 22 50245450-50261825 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025483, HPA054562 Approved Approved Nuclear speckles
Cytosol Tissue enriched 6 skeletal muscle: 91.5 cerebral cortex: 15.8 -TMEM215 ENSG00000188133 Transmembrane protein 215 9 32783499-32787399 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052804 Uncertain Group enriched 5 cervix, uterine: 1.0;endometrium: 4.8;testis: 4.2;thyroid gland: 1.8 cerebral cortex: 0.5 -NUTM2G FAM22G ENSG00000188152 NUT family member 2G 9 96928310-96940253 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA064635 Uncertain Nuclear bodies Tissue enhanced 0 testis: 2.1 skin: 1.0 -COL4A5 ASLN, ATS ENSG00000188153 Collagen, type IV, alpha 5 X 108439844-108697545 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065449 Uncertain Lipid droplets Mixed endometrium: 75.8 -KRTAP10-6 KAP10.6, KAP18.6, KRTAP18-6, KRTAP18.6 ENSG00000188155 Keratin associated protein 10-6 21 44579737-44592505 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -AGRN AGRIN ENSG00000188157 Agrin 1 1020123-1056118 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040090 Approved Supported Plasma membrane
Cytosol Expressed in all cerebral cortex: 29.4 -NHS ENSG00000188158 Nance-Horan syndrome (congenital cataracts and dental anomalies) X 17375420-17735994 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031497, HPA076257 Uncertain Supported Cell Junctions Mixed endometrium: 7.8 -OTOG FLJ46346, mlemp, OTGN ENSG00000188162 Otogelin 11 17547373-17647150 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 16 testis: 1.6 epididymis: 0.0 -FAM166A ENSG00000188163 Family with sequence similarity 166, member A 9 137243584-137247770 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023307 Supported Tissue enriched 42 testis: 58.6 epididymis: 1.3 -TMPPE FLJ45032 ENSG00000188167 Transmembrane protein with metallophosphoesterase domain 3 33090421-33096801 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA027019 Uncertain Approved Nucleoplasm
Mitochondria Mixed parathyroid gland: 4.0 -ZNF626 ENSG00000188171 Zinc finger protein 626 19 20620061-20661596 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045631 Uncertain Approved Nucleoplasm
Nuclear membrane
Vesicles Expressed in all parathyroid gland: 52.0 -HEPACAM2 FLJ38683 ENSG00000188175 HEPACAM family member 2 7 93188586-93226524 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 colon: 65.6;rectum: 104.8;small intestine: 54.7 duodenum: 31.1 -SMTNL2 FLJ42461 ENSG00000188176 Smoothelin-like 2 17 4583999-4608319 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 5 skeletal muscle: 133.8 kidney: 26.7 -ZC3H6 FLJ41410, FLJ45877, KIAA2035, ZC3HDC6 ENSG00000188177 Zinc finger CCCH-type containing 6 2 112275594-112340063 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036019, HPA036020 Uncertain Mixed ovary: 7.6 -LAMTOR4 C7orf59 ENSG00000188186 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 7 100148907-100155944 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020998 Supported Validated Vesicles Expressed in all skin: 314.2 -PRKAR1B ENSG00000188191 Protein kinase, cAMP-dependent, regulatory, type I, beta 7 549197-727650 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026719 Approved Tissue enriched 9 cerebral cortex: 239.8 ovary: 26.4 -NUTM2B bA119F19.1, FAM22B ENSG00000188199 NUT family member 2B 10 79703227-79714681 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA064635 Uncertain Nuclear bodies Mixed testis: 2.2 -NCR3LG1 B7-H6, DKFZp686O24166 ENSG00000188211 Natural killer cell cytotoxicity receptor 3 ligand 1 11 17351726-17377341 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024137 Uncertain Tissue enhanced 0 parathyroid gland: 12.6 rectum: 5.6 -DCUN1D3 DKFZp686O0290, FLJ41725, MGC48972 ENSG00000188215 DCN1, defective in cullin neddylation 1, domain containing 3 16 20854925-20900384 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041983, HPA043511 Approved Approved Nucleoplasm
Cytosol Mixed adipose tissue: 23.8 -POTEE A26C1, A26C1A, CT104.2, POTE-2, POTE2, POTE2gamma ENSG00000188219 POTE ankyrin domain family, member E 2 131218067-131265278 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041264, HPA041271, HPA042822, HPA043260 Uncertain Tissue enhanced 0 testis: 2.0 prostate: 0.7 -ZNF793 ENSG00000188227 Zinc finger protein 793 19 37506939-37548762 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA034781 Uncertain Approved Nucleus
Nucleoli
Cytosol Mixed testis: 16.8 -TUBB4B Beta2, TUBB2C ENSG00000188229 Tubulin, beta 4B class IVb 9 137241213-137243707 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010880, HPA043640, HPA046280 Supported Validated Microtubules Expressed in all testis: 787.0 -AGAP4 AGAP8, CTGLF1, CTGLF5, Em:AC012044.1, MRIP2 ENSG00000188234 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 10 45825594-45853875 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042490 Uncertain Expressed in all skin: 24.6 -COMMD6 Acrg ENSG00000188243 COMM domain containing 6 13 75525219-75549439 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 287.6 -PLA2G2A PLA2B, PLA2L ENSG00000188257 Phospholipase A2, group IIA (platelets, synovial fluid) 1 19975431-19980416 Enzymes, FDA approved drug targets, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015236 Supported Uncertain Nucleus
Nucleoli Tissue enhanced 0 colon: 111.4;rectum: 180.4;small intestine: 238.2 duodenum: 87.9 -IL17REL FLJ41993 ENSG00000188263 Interleukin 17 receptor E-like 22 49994513-50012659 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045546 Approved Tissue enhanced 0 appendix: 3.2;lymph node: 2.4;tonsil: 4.1 stomach: 2.1 -HYKK AGPHD1, LOC123688 ENSG00000188266 Hydroxylysine kinase 15 78507564-78537372 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040706 Approved Approved Vesicles
Aggresome Mixed kidney: 12.3 -OR7A5 HTPCR2 ENSG00000188269 Olfactory receptor, family 7, subfamily A, member 5 19 14792490-14835376 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053823 Uncertain Tissue enhanced 0 epididymis: 5.4;parathyroid gland: 5.2;testis: 2.8 seminal vesicle: 0.9 -C15orf62 LOC643338 ENSG00000188277 Chromosome 15 open reading frame 62 15 40770080-40772449 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044636 Approved Tissue enhanced 0 esophagus: 15.0;skin: 12.6 tonsil: 6.4 -RUFY4 FLJ46536, ZFYVE31 ENSG00000188282 RUN and FYVE domain containing 4 2 218034960-218090581 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA037980 Uncertain Tissue enhanced 0 spleen: 2.6 lymph node: 1.3 -ZNF383 FLJ35863 ENSG00000188283 Zinc finger protein 383 19 37217926-37248738 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA063945 Approved Supported Nucleus
Nuclear membrane Mixed thyroid gland: 9.3 -HES4 bHLHb42 ENSG00000188290 Hes family bHLH transcription factor 4 1 998962-1000172 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA062465 Approved Nucleoplasm
Vesicles
Cytosol Mixed cerebral cortex: 7.5 -IGFL1 UNQ644 ENSG00000188293 IGF-like family member 1 19 46229752-46231243 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014001 Uncertain Tissue enriched 21 esophagus: 98.0 tonsil: 4.7 -ZNF669 FLJ12606 ENSG00000188295 Zinc finger protein 669 1 247099962-247104372 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044043 Uncertain Approved Nucleoli Mixed testis: 8.7 -C19orf35 FLJ45778 ENSG00000188305 Chromosome 19 open reading frame 35 19 2274622-2282176 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057806 Uncertain Mixed appendix: 1.8 -LRRIQ4 LRRC64 ENSG00000188306 Leucine-rich repeats and IQ motif containing 4 3 169821922-169837775 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA036706 Uncertain Tissue enhanced 0 testis: 4.3 rectum: 1.3 -CENPP CENP-P, RP11-19J3.3 ENSG00000188312 Centromere protein P 9 92325484-92620533 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021787, HPA058945 Uncertain Supported Nucleus
Nucleoli Tissue enhanced 0 skin: 25.3 bone marrow: 7.8 -PLSCR1 MMTRA1B ENSG00000188313 Phospholipid scramblase 1 3 146515180-146544864 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA068923, CAB070421 Approved Approved Nucleus
Golgi apparatus
Plasma membrane Expressed in all appendix: 117.3 -C3orf62 FLJ43654 ENSG00000188315 Chromosome 3 open reading frame 62 3 49268602-49277909 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043328, HPA053340 Approved Approved Nuclear speckles Tissue enhanced 0 testis: 28.9 ovary: 9.4 -ENO4 AC023283.3, C10orf134 ENSG00000188316 Enolase family member 4 10 116849512-116911788 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037937, HPA037938, HPA061509 Supported Approved Mitochondria Tissue enhanced 0 fallopian tube: 14.6 testis: 9.6 -ZNF559 MGC13105 ENSG00000188321 Zinc finger protein 559 19 9323772-9351162 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA059632, HPA065485 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 39.9 -SBK1 Sbk ENSG00000188322 SH3 domain binding kinase 1 16 28292519-28323849 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 10.9;skeletal muscle: 12.0 parathyroid gland: 4.0 -OR6C6 ENSG00000188324 Olfactory receptor, family 6, subfamily C, member 6 12 55294288-55295232 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA051090 Uncertain Not detected adipose tissue: 0.0 -BSPH1 BSP1, ELSPBP2 ENSG00000188334 Binder of sperm protein homolog 1 19 47968046-47992170 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 2756 epididymis: 461.3 testis: 0.1 -SLC38A3 G17, SN1 ENSG00000188338 Solute carrier family 38, member 3 3 50205246-50221486 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031871 Approved Microtubules
Cytosol Tissue enriched 7 liver: 173.5 cerebral cortex: 25.6 -OR6N2 ENSG00000188340 Olfactory receptor, family 6, subfamily N, member 2 1 158776682-158777635 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA056637 Uncertain Tissue enriched 12 bone marrow: 1.1 adipose tissue: 0.0 -GTF2F2 BTF4, RAP30, TFIIF ENSG00000188342 General transcription factor IIF, polypeptide 2, 30kDa 13 45120515-45284909 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006912 Supported Supported Nucleus
Microtubules Expressed in all skin: 26.4 -FAM92A1 FLJ38979 ENSG00000188343 Family with sequence similarity 92, member A1 8 93698561-93731527 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034760 Uncertain Approved Mitochondria Tissue enriched 6 testis: 199.0 parathyroid gland: 35.6 -FOCAD FLJ20375, KIAA1797 ENSG00000188352 Focadhesin 9 20658309-20995955 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055015 Uncertain Uncertain Mitochondria Expressed in all thyroid gland: 34.0 -PRR19 MGC70924 ENSG00000188368 Proline rich 19 19 42302098-42310821 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA070350 Approved Nucleus
Nucleoli
Nuclear bodies Tissue enriched 10 testis: 22.5 cerebral cortex: 2.1 -ZP3 ZP3-372, ZP3-424, ZP3A, ZP3B, ZPC ENSG00000188372 Zona pellucida glycoprotein 3 (sperm receptor) 7 76397518-76442071 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA054061 Supported Mixed fallopian tube: 6.2 -C10orf99 AP-57, CSBF, FLJ21763, RLLV1833, UNQ1833 ENSG00000188373 Chromosome 10 open reading frame 99 10 84173738-84185294 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA050920 Supported Group enriched 11 colon: 243.3;esophagus: 186.2;rectum: 268.3 urinary bladder: 21.5 -H3F3C H3.5 ENSG00000188375 H3 histone, family 3C 12 31791185-31792241 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Tissue enriched 15 testis: 33.6 bone marrow: 2.2 -IFNA2 IFN-alphaA, IFNA ENSG00000188379 Interferon, alpha 2 9 21384254-21385388 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected epididymis: 0.0 -JAKMIP3 bA140A10.5, C10orf14, C10orf39, FLJ37857, KIAA4091, NECC2 ENSG00000188385 Janus kinase and microtubule interacting protein 3 10 132104671-132184809 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA022872 Uncertain Tissue enhanced 0 cerebral cortex: 5.8 prostate: 2.0 -PPP3R2 PPP3RL ENSG00000188386 Protein phosphatase 3, regulatory subunit B, beta 9 101591615-101595001 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047157 Uncertain Approved Plasma membrane
Cytosol Tissue enriched 755 testis: 75.4 adipose tissue: 0.0 -PDCD1 CD279, hSLE1, PD-1, PD1, SLEB2 ENSG00000188389 Programmed cell death 1 2 241849881-241858908 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035981, CAB038418 Supported Tissue enhanced 0 lymph node: 12.2 appendix: 3.4 -CLEC2A INPE5792, KACL, PILAR, UNQ5792 ENSG00000188393 C-type lectin domain family 2, member A 12 9898673-9932381 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048530, HPA072407 Approved Uncertain Plasma membrane Tissue enriched 14 skin: 67.7 breast: 4.7 -GPR21 ENSG00000188394 G protein-coupled receptor 21 9 123034527-123035696 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041651 Uncertain Tissue enhanced 0 cerebral cortex: 2.1 endometrium: 0.9 -TCTEX1D4 ENSG00000188396 Tctex1 domain containing 4 1 44805913-44806675 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA062652 Supported Tissue enhanced 0 fallopian tube: 5.8 epididymis: 1.6 -SELL CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR ENSG00000188404 Selectin L 1 169690667-169711698 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002144, HPA051972 Supported Uncertain Cytosol Tissue enhanced 0 lymph node: 258.2;spleen: 222.6;tonsil: 185.9 appendix: 157.5 -MAGEB5 CT3.3, MAGE-B5 ENSG00000188408 Melanoma antigen family B5 X 26216169-26218270 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA052627 Uncertain Not detected testis: 0.8 -CHM DXS540, REP-1, TCD ENSG00000188419 Choroideremia (Rab escort protein 1) X 85861180-86047562 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003231, CAB016171 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 21.6 -NANOS2 NOS2 ENSG00000188425 Nanos homolog 2 (Drosophila) 19 45913214-45914870 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014190 Approved Tissue enriched 37 testis: 3.7 adipose tissue: 0.0 -BLOC1S5 dJ303A1.3, MU, MUTED ENSG00000188428 Biogenesis of lysosomal organelles complex-1, subunit 5, muted 6 8013567-8064414 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025613, HPA077525 Uncertain Approved Vesicles Mixed parathyroid gland: 19.7 -CERKL RP26 ENSG00000188452 Ceramide kinase-like 2 181536676-181680665 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035443, HPA035444, HPA043203 Uncertain Supported Nucleoplasm
Cytosol Tissue enhanced 0 spleen: 34.7 lymph node: 24.4 -SLC24A5 JSX, OCA6 ENSG00000188467 Solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 15 48120972-48142672 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 22 skin: 9.6;testis: 3.0 breast: 0.2 -IER5L bA247A12.2 ENSG00000188483 Immediate early response 5-like 9 129175552-129178262 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA021327 Approved Approved Nucleus Mixed endometrium: 5.9 -H2AFX H2AX ENSG00000188486 H2A histone family, member X 11 119093854-119095467 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012264, HPA041189, HPA051647 Supported Supported Nucleoplasm
Nuclear speckles Expressed in all lymph node: 18.9 -INSC ENSG00000188487 Inscuteable homolog (Drosophila) 11 15112424-15247208 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039769 Approved Mixed small intestine: 2.8 -SERPINA5 PAI3, PCI, PLANH3, PROCI ENSG00000188488 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 14 94561442-94593120 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056919 Approved Mitochondria Tissue enhanced 0 adrenal gland: 516.7;liver: 406.5;testis: 816.1 gallbladder: 251.6 -C19orf54 FLJ41131 ENSG00000188493 Chromosome 19 open reading frame 54 19 40740856-40751553 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059043, HPA059628 Approved Expressed in all parathyroid gland: 12.7 -LCTL FLJ33279, KLG, KLPH ENSG00000188501 Lactase-like 15 66547179-66565979 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA071640 Approved Endoplasmic reticulum
Plasma membrane Mixed cerebral cortex: 1.0 -NCCRP1 FBXO50, LOC342897, NCCRP-1 ENSG00000188505 Non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 19 39196961-39201884 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052812 Uncertain Approved Mitochondria Group enriched 22 esophagus: 264.6;skin: 176.0;tonsil: 117.6 breast: 8.2 -KRTDAP KDAP, UNQ467 ENSG00000188508 Keratinocyte differentiation-associated protein 19 35487324-35495558 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063474 Supported Tissue enriched 11 skin: 4635.0 breast: 416.4 -COL25A1 ENSG00000188517 Collagen, type XXV, alpha 1 4 108810721-109302657 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029107 Approved Endoplasmic reticulum
Vesicles
Cytosol Tissue enhanced 0 testis: 20.4 adipose tissue: 7.5 -FAM83G FLJ41564, PAWS1 ENSG00000188522 Family with sequence similarity 83, member G 17 18968789-19004804 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023369, HPA023940 Approved Supported Cytosol Tissue enhanced 0 skin: 64.5 esophagus: 24.3 -CFAP77 C9orf171, FLJ46082 ENSG00000188523 Cilia and flagella associated protein 77 9 132410043-132573317 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA021329, HPA024647 Uncertain Approved Cytosol Group enriched 10 fallopian tube: 48.2;testis: 22.8 lung: 3.4 -SRSF10 FUSIP1, FUSIP2, PPP1R149, SFRS13, SFRS13A, SRp38, SRrp40, TASR1, TASR2 ENSG00000188529 Serine/arginine-rich splicing factor 10 1 23964804-23980927 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053805, HPA053831 Uncertain Supported Nucleoplasm Expressed in all endometrium: 100.3 -HBA2 HBA-T2 ENSG00000188536 Hemoglobin, alpha 2 16 172847-173710 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB038417, HPA043780 Supported Group enriched 26 bone marrow: 18412.0;placenta: 4269.5 spleen: 435.5 -DUSP28 DUSP26, VHP ENSG00000188542 Dual specificity phosphatase 28 2 240560054-240564014 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047456, CAB069448 Uncertain Uncertain Nuclear speckles
Cytosol Mixed skeletal muscle: 3.9 -C15orf52 FLJ43339 ENSG00000188549 Chromosome 15 open reading frame 52 15 40331452-40340967 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040484, HPA041834 Approved Approved Nucleoplasm
Cytosol Mixed thyroid gland: 50.4 -NBR1 1A1-3B, CA125, KIAA0049, M17S2 ENSG00000188554 Neighbor of BRCA1 gene 1 17 43170481-43211689 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022944, HPA022999, HPA023999 Approved Supported Nucleoplasm
Nuclear bodies
Vesicles Expressed in all testis: 259.1 -OR2G6 ENSG00000188558 Olfactory receptor, family 2, subfamily G, member 6 1 248521647-248522597 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.1 -RALGAPA2 AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2 ENSG00000188559 Ral GTPase activating protein, alpha subunit 2 (catalytic) 20 20389552-20712488 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042707, HPA043622 Uncertain Supported Plasma membrane
Cytosol Expressed in all thyroid gland: 39.8 -NDOR1 bA350O14.9, NR1 ENSG00000188566 NADPH dependent diflavin oxidoreductase 1 9 137205670-137217009 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024504 Approved Supported Nucleus
Intermediate filaments
Cytosol Mixed spleen: 12.9 -FBLL1 LOC345630 ENSG00000188573 Fibrillarin-like 1 5 168529116-168530634 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA049546 Approved Nucleus
Nucleoli fibrillar center Tissue enhanced 0 cerebral cortex: 19.1 testis: 4.4 -NKAIN2 FAM77B, TCBA1 ENSG00000188580 Na+/K+ transporting ATPase interacting 2 6 123804141-124825657 Disease related genes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045860 Approved Cytosol Tissue enriched 44 cerebral cortex: 48.0 skeletal muscle: 1.0 -KRTAP1-1 HB2A, KAP1.1, KAP1.1A, KAP1.1B ENSG00000188581 Keratin associated protein 1-1 17 41040559-41041461 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected pancreas: 0.1 -PAQR9 FLJ41938 ENSG00000188582 Progestin and adipoQ receptor family member IX 3 142949164-142963682 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052798 Uncertain Tissue enhanced 0 liver: 8.3;testis: 19.3 heart muscle: 5.2 -CFAP54 C12orf55, C12orf63, FLJ31514, FLJ44112 ENSG00000188596 Cilia and flagella associated 54 12 96489571-96875555 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039897 Supported Approved Microtubules
Cytosol Mixed testis: 10.6 -CLN3 BTS, JNCL ENSG00000188603 Ceroid-lipofuscinosis, neuronal 3 16 28477279-28495575 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063280 Uncertain Expressed in all placenta: 54.9 -FAM72B RP11-439A17.6 ENSG00000188610 Family with sequence similarity 72, member B 1 121167646-121185539 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043271, HPA067321 Uncertain Approved Vesicles
Plasma membrane
Cytosol Tissue enhanced 0 lymph node: 9.8 tonsil: 6.4 -ASAH2 ENSG00000188611 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 10 50182778-50248610 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061171 Supported Approved Focal adhesion sites Group enriched 18 duodenum: 85.8;small intestine: 72.9 stomach: 4.4 -SUMO2 SMT3B, SMT3H2 ENSG00000188612 Small ubiquitin-like modifier 2 17 75165586-75182983 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037314, HPA042123, HPA048064 Supported Approved Nucleoplasm
Nuclear bodies Expressed in all endometrium: 342.0 -NANOS1 NOS1 ENSG00000188613 Nanos homolog 1 (Drosophila) 10 119029716-119033732 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB012219 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 skeletal muscle: 13.2 thyroid gland: 11.8 -HMX3 NKX5-1 ENSG00000188620 H6 family homeobox 3 10 123135962-123137741 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA069659 Approved Nucleus
Microtubule organizing center Not detected adipose tissue: 0.3 -IGFL3 UNQ483 ENSG00000188624 IGF-like family member 3 19 46120071-46124674 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062776 Uncertain Tissue enriched 7 skin: 17.0 parathyroid gland: 2.6 -GOLGA8M ENSG00000188626 Golgin A8 family, member M 15 28701954-28738384 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 testis: 3.4;thyroid gland: 11.0 placenta: 2.4 -ZNF177 ENSG00000188629 Zinc finger protein 177 19 9363020-9382617 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA003141 Uncertain Mixed testis: 13.4 -LDOC1L dJ1033E15.2, DKFZp761O17121, Mar6, Mart6 ENSG00000188636 Leucine zipper, down-regulated in cancer 1-like 22 44492572-44498298 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA005697 Approved Approved Nuclear speckles
Cytosol Expressed in all cerebral cortex: 42.5 -DPYD DPD ENSG00000188641 Dihydropyrimidine dehydrogenase 1 97077743-97921049 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033241, HPA045210 Uncertain Expressed in all lung: 44.1 -S100A16 DT1P1A7, MGC17528, S100F ENSG00000188643 S100 calcium binding protein A16 1 153606886-153613145 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045841 Supported Validated Plasma membrane
Cytosol Tissue enhanced 0 esophagus: 1495.4 skin: 395.2 -PTAR1 ENSG00000188647 Protein prenyltransferase alpha subunit repeat containing 1 9 69709522-69759959 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021248 Uncertain Approved Microtubule organizing center
Rods & Rings Expressed in all parathyroid gland: 34.9 -CC2D2B bA248J23.4, C10orf130 ENSG00000188649 Coiled-coil and C2 domain containing 2B 10 96000091-96032684 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 5 testis: 17.8 endometrium: 3.4 -RNASE9 h461, RAK1 ENSG00000188655 Ribonuclease, RNase A family, 9 (non-active) 14 20556093-20560931 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 1181 epididymis: 118.1 parathyroid gland: 0.0 -SAXO2 DKFZp666G057, FAM154B ENSG00000188659 Stabilizer of axonemal microtubules 2 15 82262810-82284930 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA040487, HPA040833 Supported Approved Nucleoplasm
Golgi apparatus Tissue enhanced 0 fallopian tube: 94.7 testis: 28.9 -RHCE CD240CE, RH ENSG00000188672 Rh blood group, CcEe antigens 1 25362249-25430192 Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 6 bone marrow: 28.9 epididymis: 5.1 -C2orf80 GONDA1, LOC389073 ENSG00000188674 Chromosome 2 open reading frame 80 2 208165343-208190073 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042639 Approved Golgi apparatus Tissue enriched 27 cerebral cortex: 37.7 testis: 1.4 -IDO2 INDOL1 ENSG00000188676 Indoleamine 2,3-dioxygenase 2 8 39934614-40016391 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 7 liver: 2.6;placenta: 5.8 testis: 0.5 -PARVB CGI-56 ENSG00000188677 Parvin, beta 22 43999211-44172949 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062601 Approved Cytosol Expressed in all skeletal muscle: 68.6 -SLC4A5 NBC4 ENSG00000188687 Solute carrier family 4 (sodium bicarbonate cotransporter), member 5 2 74216242-74343414 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036621 Approved Group enriched 9 testis: 25.5;thyroid gland: 40.5 skin: 3.7 -UROS ENSG00000188690 Uroporphyrinogen III synthase 10 125784980-125823248 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044038 Approved Approved Nucleoplasm
Cytosol Expressed in all epididymis: 88.6 -OR56A5 OR56A5P ENSG00000188691 Olfactory receptor, family 56, subfamily A, member 5 11 5967177-5968494 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.1 -KRTAP24-1 KAP24.1 ENSG00000188694 Keratin associated protein 24-1 21 30281309-30282958 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA017604 Supported Not detected epididymis: 0.0 -ZDHHC9 CGI-89, CXorf11, ZDHHC10, ZNF379, ZNF380 ENSG00000188706 Zinc finger, DHHC-type containing 9 X 129803288-129843909 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031814 Uncertain Supported Golgi apparatus
Cytosol Expressed in all cerebral cortex: 71.2 -ZBED6CL C7orf29 ENSG00000188707 ZBED6 C-terminal like 7 150329789-150332721 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA019724, HPA055805 Approved Approved Nuclear membrane
Vesicles Tissue enhanced 0 adrenal gland: 31.9;parathyroid gland: 30.0 lymph node: 10.0 -QRFP 26RFa, P518 ENSG00000188710 Pyroglutamylated RFamide peptide 9 130892702-130896812 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043377 Uncertain Mixed prostate: 1.6 -DUPD1 DUSP27 ENSG00000188716 Dual specificity phosphatase and pro isomerase domain containing 1 10 75037836-75058514 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042964 Uncertain Tissue enriched 32 skeletal muscle: 24.4 esophagus: 0.7 -SMIM15 C5orf43, DKFZP686E2158 ENSG00000188725 Small integral membrane protein 15 5 61157709-61162474 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Expressed in all thyroid gland: 59.7 -OSTN ENSG00000188729 Osteocrin 3 191199241-191265615 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB024997, CAB025649, HPA030878 Uncertain Tissue enhanced 0 cerebral cortex: 4.4 epididymis: 2.7 -VWC2 PSST739, UNQ739 ENSG00000188730 Von Willebrand factor C domain containing 2 7 49773661-49921950 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA055243 Approved Tissue enhanced 0 heart muscle: 3.0;ovary: 6.1 cerebral cortex: 1.8 -FAM221A C7orf46, DKFZp686F0810, FLJ45875, MGC72075 ENSG00000188732 Family with sequence similarity 221, member A 7 23680130-23703249 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019719, HPA026748, HPA026752 Approved Approved Cytosol Tissue enhanced 0 testis: 34.4 fallopian tube: 14.3 -TMEM120B ENSG00000188735 Transmembrane protein 120B 12 121712752-121783001 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014066 Uncertain Mixed endometrium: 12.1 -FSIP2 FLJ34780 ENSG00000188738 Fibrous sheath interacting protein 2 2 185738628-185833290 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036139 Approved Microtubules
Mitochondria Tissue enriched 9 testis: 21.2 stomach: 2.4 -RBM34 KIAA0117 ENSG00000188739 RNA binding motif protein 34 1 235131183-235161457 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028606 Approved Supported Nucleus
Nucleoli Expressed in all testis: 34.7 -NOXA1 FLJ25475, NY-CO-31, SDCCAG31 ENSG00000188747 NADPH oxidase activator 1 9 137423350-137434406 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044781 Uncertain Approved Vesicles Expressed in all skin: 21.5 -TMEM198 MGC99813, TMEM198A ENSG00000188760 Transmembrane protein 198 2 219543663-219550595 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042385, HPA056598 Uncertain Approved Vesicles Tissue enhanced 0 cerebral cortex: 15.8 duodenum: 9.1 -BCL2L15 Bfk, C1orf178, FLJ22588 ENSG00000188761 BCL2-like 15 1 113878168-113887547 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029732, HPA029733 Approved Tissue enhanced 0 colon: 48.1;duodenum: 68.4;rectum: 52.8;small intestine: 65.6 stomach: 24.2 -FZD9 CD349, FZD3 ENSG00000188763 Frizzled class receptor 9 7 73433783-73436120 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 1.5 skeletal muscle: 1.5 -SPRED3 ENSG00000188766 Sprouty-related, EVH1 domain containing 3 19 38388421-38399587 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA071521 Uncertain Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 6.6 parathyroid gland: 2.6 -OPTC ENSG00000188770 Opticin 1 203494143-203508864 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034951, HPA034952 Supported Not detected testis: 0.6 -PLET1 C11orf34 ENSG00000188771 Placenta expressed transcript 1 11 112248479-112260860 Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA040237 Uncertain Not detected skin: 0.4 -ADRB3 ENSG00000188778 Adrenoceptor beta 3 8 37962991-37966965 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 ovary: 10.0;placenta: 4.1 gallbladder: 2.6 -SKOR1 CORL1, FUSSEL15, LBXCOR1 ENSG00000188779 SKI family transcriptional corepressor 1 15 67819704-67834561 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040673 Approved Not detected testis: 0.8 -CATSPER4 ENSG00000188782 Cation channel, sperm associated 4 1 26190561-26202968 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level HPA045257 Supported Tissue enriched 63 testis: 9.7 skin: 0.1 -PRELP prolargin, SLRR2A ENSG00000188783 Proline/arginine-rich end leucine-rich repeat protein 1 203475828-203491352 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed seminal vesicle: 107.0 -PLA2G2E ENSG00000188784 Phospholipase A2, group IIE 1 19920009-19923617 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA064085 Uncertain Tissue enriched 11 tonsil: 2.4 small intestine: 0.2 -ZNF548 FLJ32932 ENSG00000188785 Zinc finger protein 548 19 57389850-57402992 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA066042 Uncertain Approved Nucleus Expressed in all lymph node: 33.1 -MTF1 ENSG00000188786 Metal-regulatory transcription factor 1 1 37809567-37859620 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA028604, HPA028689 Uncertain Validated Nucleoplasm Mixed bone marrow: 13.2 -TMCO2 dJ39G22.2 ENSG00000188800 Transmembrane and coiled-coil domains 2 1 40245947-40251691 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 742 testis: 187.0 urinary bladder: 0.2 -SHISA6 FLJ45455 ENSG00000188803 Shisa family member 6 17 11241263-11564063 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023440 Uncertain Tissue enhanced 0 cervix, uterine: 24.6 seminal vesicle: 10.2 -TMEM201 NET5, RP13-15M17.2 ENSG00000188807 Transmembrane protein 201 1 9588922-9614873 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB039039 Approved Supported Nucleus
Nuclear membrane Mixed testis: 9.9 -NHLRC3 ENSG00000188811 NHL repeat containing 3 13 39038306-39050109 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA013738 Uncertain Expressed in all thyroid gland: 27.8 -HMX2 NKX5-2 ENSG00000188816 H6 family homeobox 2 10 123148122-123150672 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043379 Uncertain Tissue enriched 6 kidney: 1.2 duodenum: 0.2 -SNTN FLJ44379, S100AL ENSG00000188817 Sentan, cilia apical structure protein 3 63652668-63679020 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA043322, HPA058399 Supported Tissue enriched 11 fallopian tube: 344.9 thyroid gland: 32.3 -ZDHHC11 FLJ13153, ZNF399 ENSG00000188818 Zinc finger, DHHC-type containing 11 5 795606-850986 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057886, HPA069008 Uncertain Approved Lipid droplets Mixed fallopian tube: 10.7 -FAM26F C6orf187, dJ93H18.5, OTTHUMP00000017061, OTTHUMP00000017062, RP1-93H18.5 ENSG00000188820 Family with sequence similarity 26, member F 6 116461370-116463779 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 spleen: 173.5 appendix: 83.3 -CNR2 CB2 ENSG00000188822 Cannabinoid receptor 2 (macrophage) 1 23870526-23913362 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009719 Uncertain Group enriched 7 appendix: 3.2;lymph node: 8.8;spleen: 8.1;tonsil: 7.2 bone marrow: 1.0 -SLX4 BTBD12, FANCP, KIAA1784, KIAA1987 ENSG00000188827 SLX4 structure-specific endonuclease subunit 16 3581181-3611598 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049421, HPA066238 Approved Supported Nucleoplasm
Cell Junctions
Cytosol Tissue enhanced 0 testis: 12.8 lymph node: 4.9 -GLRA4 ENSG00000188828 Glycine receptor, alpha 4 X 103707224-103728655 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA044759 Uncertain Tissue enhanced 0 smooth muscle: 2.7 parathyroid gland: 1.0 -ENTPD8 NTPDase-8, UNQ2492 ENSG00000188833 Ectonucleoside triphosphate diphosphohydrolase 8 9 137434364-137441816 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021509 Supported Approved Nucleoplasm
Vesicles
Cytosol Tissue enhanced 0 colon: 22.2;duodenum: 29.5;small intestine: 32.1 rectum: 12.7 -RPL14 CTG-B33, hRL14, L14, RL14 ENSG00000188846 Ribosomal protein L14 3 40457292-40468587 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004136 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all breast: 311.2 -BEND4 CCDC4, FLJ35632, FLJ43965 ENSG00000188848 BEN domain containing 4 4 42110938-42152878 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA036850 Uncertain Approved Nucleus
Nucleoli fibrillar center
Cytosol Tissue enhanced 0 prostate: 5.2;testis: 17.7 lymph node: 2.5 -FAM78B ENSG00000188859 Family with sequence similarity 78, member B 1 166057426-166166969 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052789, HPA073246 Uncertain Approved Golgi apparatus
Vesicles Not detected adipose tissue: 0.2 -ZNF563 FLJ34797 ENSG00000188868 Zinc finger protein 563 19 12317477-12333720 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042136 Uncertain Tissue enhanced 0 testis: 25.5 thyroid gland: 8.5 -TMC3 ENSG00000188869 Transmembrane channel-like 3 15 81331217-81374213 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA040265, HPA040510 Approved Supported Cytosol Tissue enriched 79 parathyroid gland: 248.1 epididymis: 3.1 -FBF1 ALB, FBF-1, FLJ00103, KIAA1863 ENSG00000188878 Fas (TNFRSF6) binding factor 1 17 75909574-75941140 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA023677 Approved Approved Centrosome Tissue enhanced 0 testis: 32.6 skin: 15.4 -KLRG2 CLEC15B, FLJ44186 ENSG00000188883 Killer cell lectin-like receptor subfamily G, member 2 7 139452690-139483712 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018199 Uncertain Tissue enhanced 0 lung: 4.4;parathyroid gland: 5.7;thyroid gland: 6.7 kidney: 2.7 -ASTL ovastacin, SAS1B ENSG00000188886 Astacin-like metallo-endopeptidase (M12 family) 2 96123850-96138436 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA015620 Uncertain Tissue enhanced 0 bone marrow: 2.4 seminal vesicle: 1.4 -MSL1 DKFZp686P24239, hMSL1, MSL-1 ENSG00000188895 Male-specific lethal 1 homolog (Drosophila) 17 40122298-40136916 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022800, HPA023567 Uncertain Validated Nucleoplasm Expressed in all testis: 106.7 -CTD-3088G3.8 ENSG00000188897 16 11359845-11523588 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042154 Uncertain Tissue enhanced 0 appendix: 5.4 skin: 4.3 -LRRK2 DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2 ENSG00000188906 Leucine-rich repeat kinase 2 12 40196744-40369285 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014293, CAB037160 Approved Approved Nucleus
Vesicles Tissue enhanced 0 lung: 78.2 parathyroid gland: 22.9 -BSX BSX1 ENSG00000188909 Brain-specific homeobox 11 122977570-122981720 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA015654 Uncertain Not detected testis: 0.2 -GJB3 CX31, DFNA2, EKV ENSG00000188910 Gap junction protein, beta 3, 31kDa 1 34781189-34786369 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA074472 Supported Vesicles
Cell Junctions Tissue enhanced 0 esophagus: 33.7;skin: 77.4 tonsil: 12.1 -FAM196A C10orf141, FLJ45557 ENSG00000188916 Family with sequence similarity 196, member A 10 127135426-127196158 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035898, HPA035899 Uncertain Tissue enhanced 0 cerebral cortex: 3.2 testis: 1.2 -TRMT2B CXorf34, FLJ12687 ENSG00000188917 TRNA methyltransferase 2 homolog B X 101009346-101052116 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003745, HPA035120, HPA040814 Uncertain Approved Nucleoplasm
Nuclear bodies Expressed in all parathyroid gland: 21.0 -HACD4 Em:AL662879.1, PTPLAD2 ENSG00000188921 3-hydroxyacyl-CoA dehydratase 4 9 20999515-21031636 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058666 Uncertain Mixed lung: 12.6 -CFAP126 C1orf192, Flattop, Fltp ENSG00000188931 Cilia and flagella associated protein 126 1 161364731-161367874 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA045904 Supported Tissue enriched 9 fallopian tube: 224.9 testis: 24.8 -NYX CLRP, CSNB1, CSNB1A, CSNB4 ENSG00000188937 Nyctalopin X 41447434-41475710 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Not detected kidney: 0.3 -FAM120AOS C9orf10OS ENSG00000188938 Family with sequence similarity 120A opposite strand 9 93446494-93453592 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA021475 Approved Expressed in all thyroid gland: 50.1 -UTS2B U2B, URP, UTS2D ENSG00000188958 Urotensin 2B 3 191267168-191330536 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA026992 Uncertain Uncertain Mitochondria Mixed liver: 7.3 -C9orf152 bA470J20.2 ENSG00000188959 Chromosome 9 open reading frame 152 9 110190048-110208189 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA050769 Approved Supported Nucleus Tissue enhanced 0 rectum: 45.4 colon: 33.1 -NOC2L DKFZP564C186, NET15, NET7, NIR, PPP1R112 ENSG00000188976 NOC2-like nucleolar associated transcriptional repressor 1 944204-959309 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044258, HPA062195 Approved Validated Nucleoli Expressed in all skin: 42.1 -MSANTD1 C4orf44, LOC345222 ENSG00000188981 Myb/SANT-like DNA-binding domain containing 1 4 3244369-3271738 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 7 cerebral cortex: 1.9;testis: 2.5 epididymis: 0.3 -AADACL3 ENSG00000188984 Arylacetamide deacetylase-like 3 1 12716115-12728759 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 placenta: 1.3 skin: 0.7 -NELFB COBRA1, KIAA1182, NELF-B ENSG00000188986 Negative elongation factor complex member B 9 137255173-137273547 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020259 Supported Validated Nucleoplasm Expressed in all cerebral cortex: 40.6 -SLC15A5 ENSG00000188991 Solute carrier family 15, member 5 12 16188485-16277685 Predicted membrane proteins, Transporters No evidence No evidence No evidence HPA041638 Uncertain Not detected testis: 0.3 -LIPI CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5 ENSG00000188992 Lipase, member I 21 14108813-14210891 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 118 epididymis: 568.5 thyroid gland: 4.8 -LRRC66 ENSG00000188993 Leucine rich repeat containing 66 4 51993702-52017620 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014549, HPA027839 Uncertain Tissue enhanced 0 duodenum: 23.2;small intestine: 21.0 rectum: 6.5 -ZNF292 bA393I2.3, KIAA0530, ZFP292, Zn-15, Zn-16 ENSG00000188994 Zinc finger protein 292 6 87152833-87264196 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032154, HPA050618 Uncertain Approved Nucleus
Nuclear membrane Expressed in all ovary: 17.0 -HUS1B ENSG00000188996 HUS1 checkpoint clamp component B 6 655939-656963 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA034511, HPA063449 Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 1.2 bone marrow: 0.4 -KCTD21 KCASH2 ENSG00000188997 Potassium channel tetramerization domain containing 21 11 78171249-78188822 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041964 Uncertain Approved Cytosol Mixed thyroid gland: 18.7 -SBSN HLAR698, UNQ698 ENSG00000189001 Suprabasin 19 35523367-35528351 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062568, HPA067734 Supported Approved Vesicles Group enriched 12 esophagus: 1059.9;skin: 2694.5 tonsil: 158.2 -ADAT2 DEADC1, dJ20N2.1, TAD2 ENSG00000189007 Adenosine deaminase, tRNA-specific 2 6 143422832-143450673 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035479 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Mixed skin: 13.0 -KIR2DL4 103AS, 15.212, CD158D ENSG00000189013 Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 19 54803535-54814517 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Not detected spleen: 0.3 -MAGEB16 ENSG00000189023 Melanoma antigen family B16 X 35798342-35803735 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA055743 Uncertain Tissue enriched 63 testis: 6.2 epididymis: 0.0 -VHLL VHLP, VLP ENSG00000189030 Von Hippel-Lindau tumor suppressor-like 1 156298624-156299299 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.1 -DUSP21 ENSG00000189037 Dual specificity phosphatase 21 X 44844004-44844888 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 40 testis: 9.9 small intestine: 0.2 -ZNF567 MGC45586 ENSG00000189042 Zinc finger protein 567 19 36687612-36727701 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA023937 Uncertain Approved Nucleoplasm
Cytosol Mixed testis: 16.1 -NDUFA4 CI-9k, MLRQ ENSG00000189043 NDUFA4, mitochondrial complex associated 7 10931951-10940256 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055323 Supported Mitochondria Expressed in all heart muscle: 249.3 -ANKDD1B ENSG00000189045 Ankyrin repeat and death domain containing 1B 5 75611459-75671846 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA059722 Uncertain Tissue enhanced 0 fallopian tube: 3.5 rectum: 2.5 -ALKBH2 ABH2, MGC90512 ENSG00000189046 AlkB homolog 2, alpha-ketoglutarate-dependent dioxygenase 12 109088188-109093631 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011198, HPA045392, HPA051976 Approved Validated Nucleus Expressed in all skin: 27.1 -RNFT1 PTD016 ENSG00000189050 Ring finger protein, transmembrane 1 17 59952240-59964761 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA013739 Approved Nucleoli Tissue enriched 9 testis: 113.2 epididymis: 12.3 -RNF222 ENSG00000189051 Ring finger protein 222 17 8390704-8397826 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA048916 Uncertain Group enriched 6 esophagus: 9.8;skin: 4.2;tonsil: 2.2 bone marrow: 0.9 -CGB5 HCG ENSG00000189052 Chorionic gonadotropin, beta polypeptide 5 19 49043884-49045311 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038925, HPA038934 Supported Approved Cytosol Tissue enriched 67 placenta: 31.7 testis: 0.4 -RELN PRO1598, RL ENSG00000189056 Reelin 7 103471784-103989516 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046512 Approved Plasma membrane
Focal adhesion sites Tissue enhanced 0 liver: 17.8 cerebral cortex: 7.3 -FAM111B CANP ENSG00000189057 Family with sequence similarity 111, member B 11 59107185-59127410 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038637 Uncertain Approved Nucleus
Cytosol Mixed lymph node: 15.1 -APOD ENSG00000189058 Apolipoprotein D 3 195568702-195584205 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040520 Supported Tissue enriched 7 breast: 4546.8 adipose tissue: 668.0 -H1F0 H10, H1FV ENSG00000189060 H1 histone family, member 0 22 37805093-37807436 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000843 Supported Supported Nucleus
Nuclear bodies
Golgi apparatus
Actin filaments Expressed in all bone marrow: 420.8 -GAGE2A CT4.2, GAGE2 ENSG00000189064 G antigen 2A X 49589529-49596827 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enriched 575 testis: 181.3 cerebral cortex: 0.3 -LITAF FLJ38636, PIG7, SIMPLE, TP53I7 ENSG00000189067 Lipopolysaccharide-induced TNF factor 16 11547722-11636381 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA006960 Approved Supported Nucleoplasm
Vesicles
Cytosol Expressed in all appendix: 231.9 -VSTM1 UNQ3033 ENSG00000189068 V-set and transmembrane domain containing 1 19 54040825-54063953 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059365 Approved Vesicles Tissue enriched 37 bone marrow: 35.4 urinary bladder: 0.9 -TMEM120A NET29, TMPIT ENSG00000189077 Transmembrane protein 120A 7 75986837-75994659 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all small intestine: 73.9 -ARID2 BAF200, DKFZp686G052, FLJ30619, KIAA1557 ENSG00000189079 AT rich interactive domain 2 (ARID, RFX-like) 12 45729665-45908040 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063044 Supported Nucleoplasm
Plasma membrane Expressed in all testis: 47.3 -FAM25G bA301J7.4 ENSG00000189090 Family with sequence similarity 25, member G 10 47487219-47491693 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA044808 Uncertain Tissue enriched 15 skin: 86.9 breast: 5.8 -SF3B3 KIAA0017, RSE1, SAP130, SF3b130 ENSG00000189091 Splicing factor 3b, subunit 3, 130kDa 16 70523788-70577670 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041134, HPA042986 Supported Supported Nucleus
Nucleoli Expressed in all parathyroid gland: 40.9 -PRSS48 ESSPL ENSG00000189099 Protease, serine, 48 4 151277171-151291453 Enzymes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053801 Uncertain Tissue enhanced 0 testis: 1.4 skin: 0.4 -IL1RAPL2 IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1 ENSG00000189108 Interleukin 1 receptor accessory protein-like 2 X 104566315-105767829 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036128, HPA036129 Uncertain Tissue enhanced 0 parathyroid gland: 4.7 adrenal gland: 1.9 -BLOC1S3 BLOS3, HPS8 ENSG00000189114 Biogenesis of lysosomal organelles complex-1, subunit 3 19 45178745-45181801 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050111 Approved Golgi apparatus Mixed skin: 12.2 -SP6 Epfn, KLF14 ENSG00000189120 Sp6 transcription factor 17 47844908-47855874 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024516, HPA044469 Supported Nucleoplasm
Mitotic spindle
Centrosome Tissue enhanced 0 placenta: 32.3;seminal vesicle: 14.6 skin: 7.2 -ANKRD34B DP58 ENSG00000189127 Ankyrin repeat domain 34B 5 80556755-80570488 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA043327, HPA061740 Uncertain Approved Lipid droplets Tissue enhanced 0 bone marrow: 1.1;lymph node: 1.0;tonsil: 1.2 kidney: 0.7 -PLAC9 ENSG00000189129 Placenta-specific 9 10 80131682-80145359 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043469 Uncertain Tissue enhanced 0 adipose tissue: 87.2 breast: 67.5 -FAM47B FLJ35782 ENSG00000189132 Family with sequence similarity 47, member B X 34942796-34944915 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046829, HPA050996 Uncertain Tissue enriched 133 testis: 13.2 adipose tissue: 0.0 -NKAPL bA424I5.1, C6orf194 ENSG00000189134 NFKB activating protein-like 6 28259320-28260958 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 15 testis: 53.3 seminal vesicle: 3.5 -FSCB C14orf155, DKFZP434F1017 ENSG00000189139 Fibrous sheath CABYR binding protein 14 44504342-44507279 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA003546 Supported Tissue enriched 516 testis: 51.6 adipose tissue: 0.0 -CLDN4 CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8 ENSG00000189143 Claudin 4 7 73799542-73832693 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002610 Supported Supported Plasma membrane Mixed colon: 212.3 -ZNF573 FLJ30921 ENSG00000189144 Zinc finger protein 573 19 37735833-37817300 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042776 Uncertain Approved Intermediate filaments
Cytosol Mixed testis: 4.5 -GRAPL ENSG00000189152 GRB2-related adaptor protein-like 17 19127469-19159176 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA051796, HPA066654 Uncertain Approved Centrosome Tissue enhanced 0 lymph node: 27.1;spleen: 32.6 tonsil: 22.4 -FAM47E FLJ42946, LOC100129583 ENSG00000189157 Family with sequence similarity 47, member E 4 76214040-76283780 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053331 Uncertain Uncertain Plasma membrane
Cytosol Tissue enhanced 0 fallopian tube: 26.5 thyroid gland: 13.8 -HN1 ARM2, HN1A ENSG00000189159 Hematological and neurological expressed 1 17 75135248-75168281 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059729 Approved Supported Nucleus
Nuclear membrane
Nucleoli Expressed in all testis: 421.3 -ZNF527 KIAA1829 ENSG00000189164 Zinc finger protein 527 19 37371061-37393066 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037740, HPA037741 Uncertain Approved Nuclear speckles
Golgi apparatus Mixed parathyroid gland: 4.5 -ZAR1L Z3CXXC7 ENSG00000189167 Zygote arrest 1-like 13 32303700-32315344 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA041319 Uncertain Not detected testis: 0.7 -KRTAP10-12 KAP10.12, KRTAP18-12, KRTAP18.12 ENSG00000189169 Keratin associated protein 10-12 21 44697172-44698044 Predicted intracellular proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected epididymis: 0.0 -S100A13 ENSG00000189171 S100 calcium binding protein A13 1 153618787-153631360 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019592, CAB025494 Approved Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Expressed in all thyroid gland: 330.1 -ZNF33A FLJ23404, KIAA0065, KOX31, KOX5, ZNF11A, ZNF33, ZZAPK ENSG00000189180 Zinc finger protein 33A 10 38010650-38065088 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005538, HPA056638 Approved Uncertain Nucleoli
Endoplasmic reticulum Expressed in all parathyroid gland: 34.5 -OR14I1 OR5BU1, OR5BU1P ENSG00000189181 Olfactory receptor, family 14, subfamily I, member 1 1 248681369-248682304 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enriched 6 cerebral cortex: 3.4 prostate: 0.6 -KRT77 KRT1B ENSG00000189182 Keratin 77, type II 12 52689626-52703463 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045934 Supported Approved Nuclear membrane
Plasma membrane Tissue enriched 12 skin: 309.5 breast: 25.9 -PCDH18 KIAA1562, PCDH68L ENSG00000189184 Protocadherin 18 4 137518918-137532494 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA017976 Approved Approved Golgi apparatus
Cytosol Mixed placenta: 64.0 -DCAF8L2 WDR42C ENSG00000189186 DDB1 and CUL4 associated factor 8-like 2 X 27590382-27748821 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 52 testis: 40.4 ovary: 0.7 -ZNF600 DKFZp686F06123, KR-ZNF1 ENSG00000189190 Zinc finger protein 600 19 52764195-52818004 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed spleen: 8.1 -BTBD8 ENSG00000189195 BTB (POZ) domain containing 8 1 92080305-92147836 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA035311, HPA035312 Uncertain Supported Nucleoplasm Mixed parathyroid gland: 4.0 -MAOA ENSG00000189221 Monoamine oxidase A X 43654907-43746824 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009437, HPA054807, HPA059299 Supported Validated Mitochondria Mixed small intestine: 253.2 -C15orf61 LOC145853 ENSG00000189227 Chromosome 15 open reading frame 61 15 67521068-67530143 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062820 Approved Nucleoli
Vesicles
Cytosol Mixed cerebral cortex: 11.0 -NUGGC C8orf80, HMFN0672, SLIP-GC ENSG00000189233 Nuclear GTPase, germinal center associated 8 28021964-28083871 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 23.2;tonsil: 22.4 liver: 11.0 -TSPYL1 TSPYL ENSG00000189241 TSPY-like 1 6 116276578-116279903 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031970, HPA031971 Approved Supported Nucleus
Nucleoli Expressed in all cerebral cortex: 192.5 -SPANXN3 CT11.8, SPANX-N3 ENSG00000189252 SPANX family, member N3 X 143508735-143517475 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045652 Approved Nucleus
Nucleoli fibrillar center Tissue enriched 26 testis: 51.9 epididymis: 2.0 -TRIM64B ENSG00000189253 Tripartite motif containing 64B 11 89869282-89876017 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA045370 Approved Tissue enriched 13 placenta: 3.0 epididymis: 0.2 -PNRC2 ENSG00000189266 Proline-rich nuclear receptor coactivator 2 1 23959109-23963462 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA027820, HPA045837 Uncertain Supported Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 202.7 -DRICH1 C22orf43 ENSG00000189269 Aspartate-rich 1 22 23608452-23632321 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA020446 Approved Nucleus
Nucleoli Group enriched 8 epididymis: 20.4;parathyroid gland: 23.4;testis: 81.1 endometrium: 5.3 -GJB5 CX31.1 ENSG00000189280 Gap junction protein, beta 5, 31.1kDa 1 34755047-34758512 Cancer-related genes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA038146 Uncertain Group enriched 6 esophagus: 56.7;skin: 77.6 tonsil: 11.9 -FHIT AP3Aase, FRA3B ENSG00000189283 Fragile histidine triad 3 59749310-61251459 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002684, HPA018840, HPA018909 Supported Approved Nucleoli fibrillar center
Plasma membrane Expressed in all kidney: 26.6 -FAM150B ENSG00000189292 Family with sequence similarity 150, member B 2 279558-288851 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adrenal gland: 258.3 ovary: 82.8 -ZKSCAN3 ZF47, Zfp47, ZNF306, ZNF309, ZSCAN35 ENSG00000189298 Zinc finger with KRAB and SCAN domains 3 6 28349914-28369177 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA009637 Approved Supported Nucleoplasm Mixed parathyroid gland: 9.9 -FOXR2 FOXN6, MGC21658 ENSG00000189299 Forkhead box R2 X 55623400-55625325 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA034487, HPA057358 Uncertain Uncertain Nucleoplasm
Nuclear bodies Tissue enriched 15 testis: 2.8 epididymis: 0.1 -RRP7A CGI-96 ENSG00000189306 Ribosomal RNA processing 7 homolog A 22 42509968-42519802 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001586, HPA046768 Approved Approved Nucleus
Nucleoli
Cell Junctions Expressed in all epididymis: 49.0 -LIN54 CXCDC1, DKFZp686L1814, JC8.6, MIP120 ENSG00000189308 Lin-54 DREAM MuvB core complex component 4 82909973-83012926 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056606 Approved Approved Cytosol Mixed thyroid gland: 17.2 -FAM53B bA12J10.2, KIAA0140, smp ENSG00000189319 Family with sequence similarity 53, member B 10 124619292-124744269 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037751, HPA037752 Approved Approved Cytosol Mixed lymph node: 38.4 -FAM180A HWKM1940, UNQ1940 ENSG00000189320 Family with sequence similarity 180, member A 7 135728348-135748846 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA021224 Uncertain Tissue enhanced 0 gallbladder: 25.6 ovary: 9.9 -C6orf222 DKFZp779B1540 ENSG00000189325 Chromosome 6 open reading frame 222 6 36315757-36336885 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038407, HPA058189 Uncertain Tissue enhanced 0 duodenum: 25.4;small intestine: 26.9 rectum: 6.4 -SPANXN4 CT11.9, SPANX-N4 ENSG00000189326 SPANX family, member N4 X 143025918-143034702 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA045730 Uncertain Tissue enriched 227 testis: 22.6 epididymis: 0.0 -S100A14 BCMP84, S100A15 ENSG00000189334 S100 calcium binding protein A14 1 153614255-153616986 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027613 Supported Supported Nuclear bodies
Cell Junctions
Cytosol Tissue enhanced 0 esophagus: 2214.5 skin: 592.3 -KAZN FLJ43806, KAZRIN, KIAA1026 ENSG00000189337 Kazrin, periplakin interacting protein 1 14598704-15118043 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032095, HPA032096 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 spleen: 120.2 parathyroid gland: 47.2 -SLC35E2B ENSG00000189339 Solute carrier family 35, member E2B 1 1659529-1692728 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045641, HPA062711 Uncertain Uncertain Nucleus Expressed in all smooth muscle: 47.0 -FAM179A FLJ43249, LOC165186 ENSG00000189350 Family with sequence similarity 179, member A 2 28956611-29061373 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037561, HPA037562 Uncertain Tissue enriched 5 fallopian tube: 13.5 testis: 2.6 -SPATA31D4 FAM75D4, FLJ43859 ENSG00000189357 SPATA31 subfamily D, member 4 9 81928514-81934948 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enriched 47 testis: 4.6 epididymis: 0.0 -NEMP2 TMEM194B ENSG00000189362 Nuclear envelope integral membrane protein 2 2 190504342-190534722 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057719 Approved Nucleoplasm Mixed testis: 5.8 -ALG1L ALG1L1 ENSG00000189366 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 3 125929275-125937039 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036108 Uncertain Tissue enhanced 0 epididymis: 12.5;urinary bladder: 15.4 skin: 6.8 -KIAA0408 ENSG00000189367 KIAA0408 6 127440343-127459391 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044035 Uncertain Approved Centrosome
Cytosol Tissue enhanced 0 cerebral cortex: 43.9 lung: 30.7 -GSPT2 eRF3b, FLJ10441 ENSG00000189369 G1 to S phase transition 2 X 51743431-51746232 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044769 Approved Supported Cytosol Expressed in all testis: 24.4 -TBC1D28 FLJ40244 ENSG00000189375 TBC1 domain family, member 28 17 18635006-18661950 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 69 testis: 18.3 tonsil: 0.2 -C8orf76 FLJ14825 ENSG00000189376 Chromosome 8 open reading frame 76 8 123219957-123241398 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023708 Uncertain Uncertain Nucleoplasm
Cytosol Expressed in all placenta: 16.0 -CXCL17 Dcip1, DMC, UNQ473, VCC1 ENSG00000189377 Chemokine (C-X-C motif) ligand 17 19 42428288-42443048 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 esophagus: 83.4;lung: 193.4;stomach: 287.8 fallopian tube: 37.3 -OTUD6A DUBA2, FLJ25831, HSHIN6 ENSG00000189401 OTU deubiquitinase 6A X 70062491-70064179 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053304 Supported Tissue enriched 14 testis: 9.5 thyroid gland: 0.7 -HMGB1 DKFZp686A04236, HMG1, HMG3, SBP-1 ENSG00000189403 High mobility group box 1 13 30456704-30617597 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003506, CAB005873 Supported Supported Nucleus Expressed in all lymph node: 792.0 -MMP23B MIFR, MIFR-1, MMP22 ENSG00000189409 Matrix metallopeptidase 23B 1 1632095-1701810 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed placenta: 4.4 -SH2D5 ENSG00000189410 SH2 domain containing 5 1 20719732-20732837 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030182 Supported Cytosol Group enriched 7 cerebral cortex: 16.6;placenta: 5.1;testis: 10.5 thyroid gland: 1.5 -ZFP92 ZNF897 ENSG00000189420 ZFP92 zinc finger protein X 153418322-153426481 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003030 Uncertain Mixed fallopian tube: 5.2 -NCR1 CD335, LY94, NK-p46, NKP46 ENSG00000189430 Natural cytotoxicity triggering receptor 1 19 54906150-54916140 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049311 Approved Endoplasmic reticulum Tissue enhanced 0 spleen: 2.0 bone marrow: 0.5 -RASSF10 ENSG00000189431 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 11 13009577-13012106 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 5.3 parathyroid gland: 3.8 -GJB4 CX30.3 ENSG00000189433 Gap junction protein, beta 4, 30.3kDa 1 34759741-34763724 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA055112 Supported Cell Junctions Tissue enriched 5 skin: 27.8 epididymis: 5.0 -OR2L13 OR2L14 ENSG00000196071 Olfactory receptor, family 2, subfamily L, member 13 1 247937191-248100922 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 4.0 prostate: 1.1 -BLOC1S2 BLOS2, BORCS2, FLJ30135, MGC10120 ENSG00000196072 Biogenesis of lysosomal organelles complex-1, subunit 2 10 100273280-100286712 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048088, HPA055010 Approved Expressed in all cerebral cortex: 102.1 -SYCP2 SCP2 ENSG00000196074 Synaptonemal complex protein 2 20 59863563-59933655 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA062401, HPA065613 Supported Nucleoplasm
Plasma membrane
Cytosol Group enriched 8 breast: 17.5;testis: 76.3 stomach: 5.8 -ZNF724P ENSG00000196081 Zinc finger protein 724, pseudogene 19 23221599-23250390 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence Mixed esophagus: 3.1 -IL1RAP C3orf13, IL-1RAcP, IL1R3 ENSG00000196083 Interleukin 1 receptor accessory protein 3 190514051-190659750 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035293 Uncertain Approved Vesicles
Cytosol Tissue enhanced 0 liver: 112.5;placenta: 53.2 gallbladder: 19.9 -PTPRT KIAA0283, RPTPrho ENSG00000196090 Protein tyrosine phosphatase, receptor type, T 20 42072752-43189970 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017336, CAB069423 Approved Group enriched 5 cerebral cortex: 24.4;fallopian tube: 17.2 placenta: 3.9 -MYBPC1 ENSG00000196091 Myosin binding protein C, slow type 12 101568353-101686018 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021004, HPA027614 Supported Tissue enriched 37 skeletal muscle: 3919.3 prostate: 106.5 -PAX5 BSAP ENSG00000196092 Paired box 5 9 36833275-37034185 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026269, CAB026869, HPA056394, HPA068498 Supported Approved Nucleoplasm
Vesicles
Cytosol Tissue enhanced 0 lymph node: 49.1;spleen: 26.7;tonsil: 35.2 appendix: 20.2 -OR5K4 ENSG00000196098 Olfactory receptor, family 5, subfamily K, member 4 3 98353854-98354819 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence No evidence Evidence at protein level Not detected epididymis: 0.0 -OR6M1 ENSG00000196099 Olfactory receptor, family 6, subfamily M, member 1 11 123805335-123806387 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA048674 Uncertain Not detected testis: 0.3 -SPOCK3 testican-3 ENSG00000196104 Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 4 166733384-167234796 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA075020 Approved Nucleus
Nucleoli
Golgi apparatus Tissue enriched 7 parathyroid gland: 791.1 prostate: 113.9 -ZNF676 ENSG00000196109 Zinc finger protein 676 19 22179091-22196951 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 parathyroid gland: 4.3;testis: 4.0 thyroid gland: 3.0 -ZNF699 FLJ38144, hang ENSG00000196110 Zinc finger protein 699 19 9294275-9309838 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA058287 Uncertain Mixed parathyroid gland: 4.8 -TDRD7 PCTAIRE2BP ENSG00000196116 Tudor domain containing 7 9 97411950-97496125 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB020800, HPA024529 Approved Expressed in all testis: 63.8 -CCDC189 C16orf93, MGC104706 ENSG00000196118 Coiled-coil domain containing 189 16 30757423-30762710 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA041806, HPA046289 Approved Supported Cytosol Tissue enhanced 0 fallopian tube: 13.0 testis: 8.1 -OR8A1 OST025 ENSG00000196119 Olfactory receptor, family 8, subfamily A, member 1 11 124569997-124571142 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.4 -KIAA0895L LOC653319 ENSG00000196123 KIAA0895-like 16 67175602-67184040 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA065996 Approved Approved Nucleoplasm
Vesicles Mixed cerebral cortex: 25.4 -HLA-DRB1 HLA-DR1B ENSG00000196126 Major histocompatibility complex, class II, DR beta 1 6 32552990-32589848 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015400, CAB034021, HPA043151 Supported Tissue enhanced 0 lung: 870.8 lymph node: 634.1 -VN1R2 V1RL2 ENSG00000196131 Vomeronasal 1 receptor 2 19 53258292-53261837 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044551 Uncertain Mixed small intestine: 2.5 -MYT1 MTF1, MYTI, NZF2, PLPB1, ZC2HC4A ENSG00000196132 Myelin transcription factor 1 20 64151791-64242253 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006303 Uncertain Supported Nucleoplasm
Cytosol Group enriched 7 adrenal gland: 2.5;cerebral cortex: 5.7 testis: 0.6 -SERPINA3 AACT, ACT, alpha-1-antichymotrypsin ENSG00000196136 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 14 94612384-94624055 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000893, HPA002560, CAB016647 Supported Group enriched 5 cervix, uterine: 133.1;liver: 607.5 gallbladder: 69.4 -AKR1C3 DDX, HAKRB, HSD17B5, KIAA0119, PGFS ENSG00000196139 Aldo-keto reductase family 1, member C3 10 5035354-5107686 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010874, HPA068265 Approved Approved Nucleus
Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Expressed in all duodenum: 154.7 -SPATS2L DNAPTP6 ENSG00000196141 Spermatogenesis associated, serine-rich 2-like 2 200305881-200482263 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055427, HPA066310 Uncertain Validated Nucleoli
Cytosol Expressed in all gallbladder: 168.1 -ZNF250 MGC9718, ZFP647, ZNF647 ENSG00000196150 Zinc finger protein 250 8 144876497-144902168 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020853 Uncertain Supported Nuclear speckles Expressed in all thyroid gland: 20.1 -WDSUB1 FLJ36175, UBOX6, WDSAM1 ENSG00000196151 WD repeat, sterile alpha motif and U-box domain containing 1 2 159235793-159286799 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036840, HPA058172 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all thyroid gland: 27.9 -ZNF79 pT7 ENSG00000196152 Zinc finger protein 79 9 127424374-127445372 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA028977 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Mixed testis: 11.4 -S100A4 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98 ENSG00000196154 S100 calcium binding protein A4 1 153543613-153550136 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002618, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228 Supported Validated Plasma membrane Expressed in all lung: 990.8 -PLEKHG4 ARHGEF44, DKFZP434I216, SCA4 ENSG00000196155 Pleckstrin homology domain containing, family G (with RhoGef domain) member 4 16 67277510-67289499 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055696 Approved Cell Junctions Tissue enhanced 0 testis: 41.3 ovary: 18.7 -KRTAP4-3 KAP4.3 ENSG00000196156 Keratin associated protein 4-3 17 41167231-41168194 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Not detected epididymis: 0.0 -FAT4 CDHF14, CDHR11, FAT-J ENSG00000196159 FAT atypical cadherin 4 4 125316399-125492932 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052819 Approved Approved Cytosol Mixed parathyroid gland: 9.4 -C8orf86 FLJ43582 ENSG00000196166 Chromosome 8 open reading frame 86 8 38510834-38528662 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA025066 Uncertain Tissue enhanced 0 duodenum: 1.0 small intestine: 0.5 -KIF19 FLJ37300, KIF19A ENSG00000196169 Kinesin family member 19 17 74326210-74355820 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043638, HPA073303 Approved Approved Plasma membrane
Actin filaments
Centrosome Tissue enhanced 0 fallopian tube: 18.7;spleen: 6.7 duodenum: 3.0 -OR6K2 ENSG00000196171 Olfactory receptor, family 6, subfamily K, member 2 1 158699678-158700652 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -ZNF681 FLJ31526 ENSG00000196172 Zinc finger protein 681 19 23739195-23758891 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed testis: 4.7 -ACADSB ACAD7, SBCAD ENSG00000196177 Acyl-CoA dehydrogenase, short/branched chain 10 123008979-123058311 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041458 Supported Supported Mitochondria Expressed in all liver: 186.7 -STK40 MGC4796, SgK495 ENSG00000196182 Serine/threonine kinase 40 1 36339624-36385896 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA008026 Uncertain Supported Nucleoplasm
Cytosol Expressed in all testis: 57.0 -OR10J1 HGMP07J, HSHGMP07J ENSG00000196184 Olfactory receptor, family 10, subfamily J, member 1 1 159439722-159440811 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 101 testis: 10.1 adipose tissue: 0.0 -TMEM63A KIAA0792 ENSG00000196187 Transmembrane protein 63A 1 225845536-225882369 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066504, HPA066936, HPA068918 Validated Vesicles
Microtubule organizing center Expressed in all cerebral cortex: 77.4 -CTSE ENSG00000196188 Cathepsin E 1 206009264-206023909 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012940, CAB032687 Supported Group enriched 9 duodenum: 235.5;stomach: 1126.5 lung: 74.6 -SEMA4A CORD10, FLJ12287, SEMAB, SemB ENSG00000196189 Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 1 156147366-156177752 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053726, HPA066006, HPA069136 Supported Validated Nucleus Mixed epididymis: 61.2 -HRCT1 LGLL338, PRO537, UNQ338 ENSG00000196196 Histidine rich carboxyl terminus 1 9 35906192-35907141 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA067038 Approved Nucleoplasm Tissue enhanced 0 adipose tissue: 18.1 colon: 13.5 -MPHOSPH8 HSMPP8, mpp8 ENSG00000196199 M-phase phosphoprotein 8 13 19633681-19673459 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039701, HPA040035 Supported Supported Nucleus
Plasma membrane
Cytosol Expressed in all ovary: 64.5 -GREB1 KIAA0575 ENSG00000196208 Growth regulation by estrogen in breast cancer 1 2 11482341-11642788 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024616, HPA027843, HPA028416 Uncertain Approved Mitochondria
Cytosol Tissue enhanced 0 ovary: 156.7 prostate: 54.3 -SIRPB2 dJ776F14.2, PTPN1L, PTPNS1L3 ENSG00000196209 Signal-regulatory protein beta 2 20 1470741-1491587 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA011548, HPA048032 Uncertain Approved Nuclear bodies Tissue enhanced 0 appendix: 17.4 placenta: 10.8 -ZNF766 ENSG00000196214 Zinc finger protein 766 19 52269571-52296046 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA044882, HPA063496 Uncertain Supported Centrosome Expressed in all testis: 43.5 -RYR1 CCO, MHS, MHS1, PPP1R137, RYR ENSG00000196218 Ryanodine receptor 1 (skeletal) 19 38433699-38587564 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056416 Supported Approved Golgi apparatus
Vesicles
Cytosol Tissue enriched 30 skeletal muscle: 572.4 esophagus: 18.7 -SRGAP3 ARHGAP14, KIAA0411, MEGAP, SRGAP2, WRP ENSG00000196220 SLIT-ROBO Rho GTPase activating protein 3 3 8980591-9363053 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036959, HPA044074 Supported Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 26.6;fallopian tube: 17.3 cervix: 7.9 -KRTAP5-3 KRTAP5-9, KRTAP5.3 ENSG00000196224 Keratin associated protein 5-3 11 1607565-1608463 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -FAM217B C20orf177, dJ551D2.5 ENSG00000196227 Family with sequence similarity 217, member B 20 59933764-59948680 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA041021, HPA056698 Approved Supported Nucleoplasm Mixed cerebral cortex: 35.0 -SULT1C3 ENSG00000196228 Sulfotransferase family, cytosolic, 1C, member 3 2 108247195-108265351 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 135 breast: 441.2 duodenum: 3.2 -TUBB M40, MGC16435, OK/SW-cl.56, Tubb5 ENSG00000196230 Tubulin, beta class I 6 30720201-30725426 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005417, CAB012406, HPA043640, HPA046280 Supported Validated Microtubules Expressed in all ovary: 71.9 -LCOR FLJ38026, KIAA1795, MLR2 ENSG00000196233 Ligand dependent nuclear receptor corepressor 10 96832260-96981043 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031428, HPA031429, HPA077000 Approved Approved Nucleoplasm Expressed in all bone marrow: 18.3 -SUPT5H FLJ34157, SPT5, SPT5H ENSG00000196235 SPT5 homolog, DSIF elongation factor subunit 19 39436156-39476670 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029273, CAB034370 Supported Validated Nucleoplasm Expressed in all testis: 169.9 -XPNPEP3 APP3, ICP55, NPHPL1 ENSG00000196236 X-prolyl aminopeptidase 3, mitochondrial 22 40857077-40932815 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000527 Approved Mixed duodenum: 14.9 -OR2T2 OR2T2P ENSG00000196240 Olfactory receptor, family 2, subfamily T, member 2 1 248452798-248453772 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -OR2C3 OR2C4, OR2C5P, OST742 ENSG00000196242 Olfactory receptor, family 2, subfamily C, member 3 1 247530132-247533839 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA053920, HPA058578 Uncertain Supported Plasma membrane Expressed in all parathyroid gland: 26.6 -ZNF107 smap-7, ZFD25, ZNF588 ENSG00000196247 Zinc finger protein 107 7 64666083-64711582 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed lymph node: 19.7 -OR10S1 ENSG00000196248 Olfactory receptor, family 10, subfamily S, member 1 11 123976661-123977781 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA019038 Uncertain Not detected thyroid gland: 0.1 -SFTA2 SFTPG ENSG00000196260 Surfactant associated 2 6 30931353-30955636 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 lung: 59.9 esophagus: 5.4 -PPIA CYPA ENSG00000196262 Peptidylprolyl isomerase A (cyclophilin A) 7 44796680-44824564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004655, HPA058345 Uncertain Expressed in all breast: 1666.2 -ZNF471 KIAA1396, Z1971 ENSG00000196263 Zinc finger protein 471 19 56507843-56530221 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA066695 Uncertain Supported Nucleus Mixed ovary: 28.0 -OR10J3 OR10J3P ENSG00000196266 Olfactory receptor, family 10, subfamily J, member 3 1 159313670-159314659 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA042963 Uncertain Not detected placenta: 0.6 -ZNF836 FLJ16287 ENSG00000196267 Zinc finger protein 836 19 52153864-52171643 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed adrenal gland: 34.9 -ZNF493 FLJ36504 ENSG00000196268 Zinc finger protein 493 19 21397119-21427573 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Expressed in all thyroid gland: 34.6 -GTF2IRD2 FLJ37938, GTF2IRD2A ENSG00000196275 GTF2I repeat domain containing 2 7 74796144-74851551 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA056679, HPA056680 Approved Nucleoplasm Expressed in all ovary: 16.2 -GRM7 GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87 ENSG00000196277 Glutamate receptor, metabotropic 7 3 6770001-7741533 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015964 Uncertain Cytosol Tissue enhanced 0 cerebral cortex: 10.1;parathyroid gland: 7.0 smooth muscle: 3.4 -SUPT3H SPT3, SPT3L ENSG00000196284 SPT3 homolog, SAGA and STAGA complex component 6 44809317-45377953 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024371 Supported Supported Nucleoplasm Mixed prostate: 14.2 -BECN2 BECN1P1 ENSG00000196289 Beclin 2 1 241957767-241959062 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -NIF3L1 ALS2CR1, CALS-7, MDS015 ENSG00000196290 NIF3 NGG1 interacting factor 3-like 1 2 200889327-200903930 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036335, HPA036336, HPA061466 Supported Approved Vesicles Expressed in all parathyroid gland: 39.8 -ATP2A1 ATP2A, SERCA1 ENSG00000196296 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 16 28878405-28904509 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002310, CAB032706 Supported Approved Endoplasmic reticulum Tissue enriched 95 skeletal muscle: 2782.7 esophagus: 29.2 -IARS IARS1, ILRS ENSG00000196305 Isoleucyl-tRNA synthetase 9 92210207-92293756 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029806 Approved Supported Cytosol Expressed in all parathyroid gland: 139.0 -HIATL2 MGC12945 ENSG00000196312 Hippocampus abundant transcript-like 2 9 96898066-97013580 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed testis: 10.4 -POM121 DKFZP586G1822, DKFZP586P2220, KIAA0618, POM121A ENSG00000196313 POM121 transmembrane nucleoporin 7 72879365-72951440 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003710, HPA043809, HPA049817 Approved Validated Nucleoplasm
Nuclear membrane Expressed in all cerebral cortex: 30.2 -ZBTB44 BTBD15, HSPC063, ZNF851 ENSG00000196323 Zinc finger and BTB domain containing 44 11 130226677-130314686 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052589 Approved Approved Nucleoplasm Expressed in all testis: 75.4 -GIMAP5 HIMAP3, IAN4L1, IAN5 ENSG00000196329 GTPase, IMAP family member 5 7 150722253-150750033 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all lymph node: 81.6 -STK31 SgK396, TDRD8 ENSG00000196335 Serine/threonine kinase 31 7 23710167-23832513 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA023194 Supported Tissue enriched 285 testis: 111.9 duodenum: 0.3 -CGB7 CG-beta-a ENSG00000196337 Chorionic gonadotropin, beta polypeptide 7 19 49054275-49058860 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038925, HPA038934 Supported Approved Cytosol Tissue enhanced 0 skin: 3.9 testis: 1.1 -NLGN3 ASPGX1, AUTSX1, HNL3, KIAA1480 ENSG00000196338 Neuroligin 3 X 71144831-71171201 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003183 Supported Tissue enhanced 0 cerebral cortex: 62.4 seminal vesicle: 17.1 -OR8D1 OR8D3, OST004 ENSG00000196341 Olfactory receptor, family 8, subfamily D, member 1 11 124309812-124310837 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059510 Uncertain Tissue enriched 21 testis: 2.0 adipose tissue: 0.0 -ADH7 ADH-4 ENSG00000196344 Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 4 99412261-99435737 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039695 Supported Supported Plasma membrane
Cytosol Tissue enriched 6 esophagus: 216.3 tonsil: 35.9 -ZKSCAN7 FLJ12738, ZNF167, ZNF448, ZNF64, ZSCAN39 ENSG00000196345 Zinc finger with KRAB and SCAN domains 7 3 44555193-44594173 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA048312, HPA049906, HPA071850 Uncertain Validated Cytosol Mixed ovary: 4.1 -ZNF729 ENSG00000196350 Zinc finger protein 729 19 22286408-22317176 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 22 testis: 3.8 cerebral cortex: 0.1 -CD55 CR, CROM, DAF, TC ENSG00000196352 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1 207321508-207386804 Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002190, CAB010454, HPA024386 Supported Uncertain Vesicles
Midbody ring Expressed in all lung: 324.6 -CPNE4 COPN4, CPN4 ENSG00000196353 Copine IV 3 131533555-132285410 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA032036 Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 12.2;prostate: 41.7 seminal vesicle: 5.8 -ZNF565 FLJ36991 ENSG00000196357 Zinc finger protein 565 19 36182060-36246257 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA044123 Uncertain Approved Nucleoplasm
Nuclear bodies Mixed testis: 11.5 -NTNG2 KIAA1857, Lmnt2, NTNG1 ENSG00000196358 Netrin G2 9 132161676-132244534 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071290 Approved Group enriched 5 bone marrow: 26.5;cerebral cortex: 18.5;parathyroid gland: 16.0;prostate: 8.6 spleen: 3.2 -ELAVL3 DKFZp547J036, HUC, HUCL, MGC20653, PLE21 ENSG00000196361 ELAV like neuron-specific RNA binding protein 3 19 11451326-11481046 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB013066, HPA045610 Supported Approved Vesicles Tissue enriched 45 cerebral cortex: 73.0 adrenal gland: 1.6 -WDR5 CFAP89, SWD3 ENSG00000196363 WD repeat domain 5 9 134135365-134159968 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047182 Supported Nucleoplasm Expressed in all testis: 62.9 -LONP1 hLON, LonHS, PIM1, PRSS15 ENSG00000196365 Lon peptidase 1, mitochondrial 19 5691834-5720572 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002034, HPA002192 Supported Validated Nucleus
Mitochondria Expressed in all adrenal gland: 141.1 -TRRAP PAF400, TR-AP, Tra1 ENSG00000196367 Transformation/transcription domain-associated protein 7 98877933-99013243 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054376 Supported Nucleoplasm
Golgi apparatus Expressed in all parathyroid gland: 22.2 -NUDT11 DIPP3b, FLJ10628, hDIPP3beta ENSG00000196368 Nudix (nucleoside diphosphate linked moiety X)-type motif 11 X 51490011-51496596 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047027, HPA057684 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 40.2;testis: 67.4 prostate: 16.1 -SRGAP2B SRGAP2P2 ENSG00000196369 SLIT-ROBO Rho GTPase activating protein 2B 1 144887265-145095528 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Mixed skin: 21.7 -FUT4 CD15, ELFT, FCT3A, FUC-TIV ENSG00000196371 Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 11 94543840-94549898 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB000014, CAB016129 Supported Validated Vesicles Tissue enhanced 0 bone marrow: 63.0 duodenum: 12.7 -ASB13 FLJ13134, MGC19879 ENSG00000196372 Ankyrin repeat and SOCS box containing 13 10 5638867-5666595 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048293, HPA061742 Approved Approved Nucleus
Golgi apparatus Expressed in all small intestine: 28.5 -SLC35F1 C6orf169, dJ230I3.1 ENSG00000196376 Solute carrier family 35, member F1 6 117907526-118317676 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019576 Approved Approved Nucleoplasm
Microtubule organizing center
Cytosol Tissue enriched 12 cerebral cortex: 45.6 epididymis: 3.7 -ZNF34 KOX32 ENSG00000196378 Zinc finger protein 34 8 144773114-144787345 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053925, HPA060755, HPA066805 Uncertain Validated Nucleoplasm
Cytosol Expressed in all ovary: 12.8 -ZNF781 FLJ37549 ENSG00000196381 Zinc finger protein 781 19 37667751-37692322 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062512 Uncertain Approved Nucleoplasm Mixed smooth muscle: 3.6 -ZNF140 pHZ-39 ENSG00000196387 Zinc finger protein 140 12 133079838-133107544 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA048332 Uncertain Expressed in all endometrium: 14.5 -INCA1 ENSG00000196388 Inhibitor of CDK, cyclin A1 interacting protein 1 17 4988130-4997610 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA044359, HPA052401 Uncertain Approved Nucleoplasm
Nuclear bodies Tissue enhanced 0 testis: 55.7 parathyroid gland: 20.7 -ZNF774 MGC75360 ENSG00000196391 Zinc finger protein 774 15 90352245-90369146 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA030839, HPA030840 Uncertain Supported Intermediate filaments
Cytosol Mixed rectum: 8.2 -PTPN1 PTP1B ENSG00000196396 Protein tyrosine phosphatase, non-receptor type 1 20 50510321-50585241 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009329, HPA012542, CAB015217 Approved Validated Endoplasmic reticulum Expressed in all appendix: 62.0 -EVL RNB6 ENSG00000196405 Enah/Vasp-like 14 99971449-100144236 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018849, HPA019536, CAB033987 Supported Approved Vesicles
Cytosol Expressed in all cerebral cortex: 208.7 -SPANXD CT11.4, SPANXE ENSG00000196406 SPANX family, member D X 141697411-141698739 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046423 Uncertain Approved Nucleoplasm
Vesicles Tissue enriched 188 testis: 18.7 adipose tissue: 0.0 -THEM5 FLJ37964 ENSG00000196407 Thioesterase superfamily member 5 1 151847263-151853697 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 16 skin: 205.0 breast: 12.8 -NOXO1 P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28 ENSG00000196408 NADPH oxidase organizer 1 16 1978917-1984192 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA071540 Supported Tissue enhanced 0 appendix: 6.6;colon: 7.5;rectum: 6.7 duodenum: 3.4 -EPHB4 HTK, Tyro11 ENSG00000196411 EPH receptor B4 7 100802565-100827521 Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013537 Uncertain Expressed in all placenta: 50.3 -PRTN3 ACPA, AGP7, C-ANCA, MBT, P29, PR-3 ENSG00000196415 Proteinase 3 19 840960-848175 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005938, CAB017558 Supported Tissue enriched 716 bone marrow: 617.7 spleen: 0.8 -ZNF765 ENSG00000196417 Zinc finger protein 765 19 53389793-53430413 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed parathyroid gland: 12.9 -ZNF124 HZF-16, HZF16 ENSG00000196418 Zinc finger protein 124 1 247121975-247172016 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA031127 Uncertain Approved Nucleus
Nuclear membrane Mixed salivary gland: 16.8 -XRCC6 D22S671, D22S731, G22P1, KU70, ML8 ENSG00000196419 X-ray repair complementing defective repair in Chinese hamster cells 6 22 41621119-41664048 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004254, HPA047549, HPA062226 Supported Validated Nucleoplasm Expressed in all testis: 395.0 -S100A5 S100D ENSG00000196420 S100 calcium binding protein A5 1 153537147-153541765 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA064184 Approved Nucleoplasm Tissue enhanced 0 thyroid gland: 8.7 skin: 4.3 -PPP1R26 KIAA0649 ENSG00000196422 Protein phosphatase 1, regulatory subunit 26 9 135479079-135488893 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044686, HPA063817 Uncertain Validated Nucleoplasm Mixed parathyroid gland: 27.2 -NBPF4 FLJ32833 ENSG00000196427 Neuroblastoma breakpoint family, member 4 1 108223341-108244081 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045044, HPA046411, HPA047447, HPA058050 Uncertain Tissue enhanced 0 testis: 6.5 small intestine: 1.4 -TSC22D2 KIAA0669, TILZ4a, TILZ4b, TILZ4c ENSG00000196428 TSC22 domain family, member 2 3 150408335-150466431 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004926 Approved Approved Cytosol Expressed in all endometrium: 37.8 -CRYBA4 ENSG00000196431 Crystallin, beta A4 22 26621964-26630672 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071178 Supported Tissue enhanced 0 epididymis: 1.7 testis: 0.7 -ASMT ASMTY, HIOMT, HIOMTY ENSG00000196433 Acetylserotonin O-methyltransferase X 1615001-1643081 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 epididymis: 2.2 adrenal gland: 0.8 -NPIPB15 LOC440348, NPIPL2 ENSG00000196436 Nuclear pore complex interacting protein family, member B15 16 74377878-74392080 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA011188, HPA053611 Supported Approved Nucleoplasm Tissue enhanced 0 testis: 39.2 rectum: 13.4 -ZNF569 FLJ32053, ZAP1 ENSG00000196437 Zinc finger protein 569 19 37411155-37469275 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA052994 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Mixed testis: 20.7 -ARMCX4 CXorf35, GASP4, MGC40053 ENSG00000196440 Armadillo repeat containing, X-linked 4 X 101418287-101533459 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA000429, HPA051930 Uncertain Approved Nucleoplasm
Vesicles Mixed parathyroid gland: 14.1 -YRDC FLJ23476, IRIP, SUA5 ENSG00000196449 YrdC N(6)-threonylcarbamoyltransferase domain containing 1 37802944-37808185 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030147 Approved Approved Mitochondria Expressed in all bone marrow: 31.7 -ZNF777 KIAA1285 ENSG00000196453 Zinc finger protein 777 7 149431363-149461123 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003252 Approved Approved Nucleus Expressed in all cerebral cortex: 10.4 -PIK3R4 p150, VPS15 ENSG00000196455 Phosphoinositide-3-kinase, regulatory subunit 4 3 130678935-130746829 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036032, HPA036033 Approved Approved Vesicles
Microtubules Expressed in all parathyroid gland: 45.7 -ZNF775 MGC33584 ENSG00000196456 Zinc finger protein 775 7 150368790-150410597 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed cerebral cortex: 7.7 -ZNF605 ENSG00000196458 Zinc finger protein 605 12 132918308-132956306 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA061970, HPA062655 Uncertain Approved Nucleoplasm
Vesicles Mixed parathyroid gland: 11.1 -TRAPPC2 hYP38334, MIP-2A, SEDL, SEDT, TRAPPC2, TRS20, ZNF547L ENSG00000196459 Trafficking protein particle complex 2 X 13712244-13734635 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004665, HPA063308 Approved Approved Nucleoplasm
Endoplasmic reticulum
Vesicles Expressed in all lymph node: 16.6 -RFX8 FLJ42986 ENSG00000196460 RFX family member 8, lacking RFX DNA binding domain 2 101397361-101474703 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA059745 Approved Nucleoplasm
Nuclear bodies Tissue enhanced 0 bone marrow: 2.6 testis: 1.3 -MYL6B MLC1SA ENSG00000196465 Myosin, light chain 6B, alkali, smooth muscle and non-muscle 12 56152256-56159647 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038887, HPA046859, HPA063034 Supported Approved Vesicles Expressed in all skeletal muscle: 149.7 -ZNF799 HIT-40, MGC71805, ZNF842 ENSG00000196466 Zinc finger protein 799 19 12390016-12401271 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA003150, HPA018683 Supported Uncertain Nucleoplasm
Microtubule organizing center Mixed ovary: 7.6 -FGF16 MF4 ENSG00000196468 Fibroblast growth factor 16 X 77447405-77457278 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Not detected adipose tissue: 0.4 -SIAH1 hSIAH1 ENSG00000196470 Siah E3 ubiquitin protein ligase 1 16 48356364-48448402 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB018724 Supported Approved Nucleoplasm
Mitochondria Expressed in all placenta: 70.8 -GK2 GKP2, GKTA ENSG00000196475 Glycerol kinase 2 4 79406352-79408293 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA060687 Uncertain Tissue enriched 1517 testis: 151.7 adipose tissue: 0.0 -C20orf96 dJ1103G7.2 ENSG00000196476 Chromosome 20 open reading frame 96 20 270863-290778 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048649 Uncertain Approved Nucleus
Golgi apparatus Expressed in all fallopian tube: 52.9 -ESRRG NR3B3 ENSG00000196482 Estrogen-related receptor gamma 1 216503246-217137755 FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044678 Uncertain Approved Nucleus Tissue enhanced 0 parathyroid gland: 76.1 kidney: 31.1 -IPO4 FLJ23338, Imp4 ENSG00000196497 Importin 4 14 24180219-24188964 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039043, HPA064572 Uncertain Approved Cytosol Tissue enhanced 0 testis: 16.9 skin: 5.3 -NCOR2 CTG26, SMRT, SMRTE, TNRC14, TRAC-1 ENSG00000196498 Nuclear receptor corepressor 2 12 124324415-124567589 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001928 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 81.4 -SULT1A1 P-PST, STP, STP1 ENSG00000196502 Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 16 28605196-28623625 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049500, HPA051051 Supported Expressed in all duodenum: 140.4 -ARL9 ENSG00000196503 ADP-ribosylation factor-like 9 4 56505343-56524448 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA072942 Supported Approved Nucleoli
Mitochondria Tissue enhanced 0 testis: 12.6 seminal vesicle: 3.1 -PRPF40A FBP-11, FBP11, FLAF1, FLJ20585, FNBP3, HIP10, HYPA, NY-REN-6, Prp40 ENSG00000196504 PRP40 pre-mRNA processing factor 40 homolog A 2 152651593-152717997 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038272, HPA038273 Approved Validated Nuclear speckles Expressed in all testis: 49.9 -GDAP2 dJ776P7.1, FLJ20142, MACROD3 ENSG00000196505 Ganglioside induced differentiation associated protein 2 1 117863485-117929630 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046185 Approved Approved Endoplasmic reticulum Mixed parathyroid gland: 9.4 -TCEAL3 MGC15737, WEX8 ENSG00000196507 Transcription elongation factor A (SII)-like 3 X 103607451-103629690 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045564, HPA058982 Uncertain Expressed in all cerebral cortex: 98.2 -ANAPC7 APC7 ENSG00000196510 Anaphase promoting complex subunit 7 12 110372900-110403730 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009567 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 48.6 -TPK1 HTPK1, PP20 ENSG00000196511 Thiamin pyrophosphokinase 1 7 144451941-144836395 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021545, HPA021849 Approved Approved Vesicles Mixed duodenum: 14.4 -SLC6A9 GLYT1 ENSG00000196517 Solute carrier family 6 (neurotransmitter transporter, glycine), member 9 1 43991500-44031467 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA013977 Uncertain Approved Nucleus
Golgi apparatus Tissue enhanced 0 skin: 49.8 adrenal gland: 31.0 -AFAP1 AFAP, AFAP-110 ENSG00000196526 Actin filament associated protein 1 4 7758714-7939926 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015642, CAB024712 Supported Supported Actin filaments
Focal adhesion sites
Cytosol Mixed parathyroid gland: 42.1 -NACA NACA1 ENSG00000196531 Nascent polypeptide-associated complex alpha subunit 12 56712428-56731628 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA073152, HPA073648 Approved Cytosol Expressed in all ovary: 2544.0 -MYO18A KIAA0216, MysPDZ ENSG00000196535 Myosin XVIIIA 17 29073517-29180412 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019646, HPA021121 Supported Expressed in all skeletal muscle: 25.0 -OR2T3 ENSG00000196539 Olfactory receptor, family 2, subfamily T, member 3 1 248473351-248474307 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -SPTSSB ADMP, C3orf57, ssSPTb ENSG00000196542 Serine palmitoyltransferase, small subunit B 3 161344792-161372880 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047712 Approved Nuclear speckles Tissue enhanced 0 skin: 48.4;stomach: 60.1;urinary bladder: 37.7 prostate: 23.2 -BORCS6 C17orf59, FLJ20014 ENSG00000196544 BLOC-1 related complex subunit 6 17 8188333-8190907 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045415, HPA060791 Uncertain Supported Centrosome
Cytosol Expressed in all spleen: 7.1 -MAN2A2 HsT19662, MANA2X ENSG00000196547 Mannosidase, alpha, class 2A, member 2 15 90902218-90922584 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA017226 Approved Expressed in all bone marrow: 46.4 -MME CALLA, CD10, NEP ENSG00000196549 Membrane metallo-endopeptidase 3 155024124-155183729 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000013, HPA052583, HPA056072 Supported Tissue enhanced 0 duodenum: 440.1;kidney: 381.4;small intestine: 410.3 prostate: 151.9 -FAM72A MGC57827, RP11-312O7.1 ENSG00000196550 Family with sequence similarity 72, member A 1 206186179-206204414 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043271, HPA067321 Uncertain Approved Vesicles
Plasma membrane
Cytosol Mixed lymph node: 12.8 -CACNA1H Cav3.2 ENSG00000196557 Calcium channel, voltage-dependent, T type, alpha 1H subunit 16 1153241-1221771 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level HPA039125 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 ovary: 50.6 seminal vesicle: 46.9 -SULF2 HSULF-2, KIAA1247, SULF-2 ENSG00000196562 Sulfatase 2 20 47656348-47786616 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002325 Approved Expressed in all endometrium: 166.1 -HBG2 HBG-T1 ENSG00000196565 Hemoglobin, gamma G 11 5248274-5645789 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016143, HPA043234 Approved Approved Vesicles Tissue enriched 126 placenta: 20295.9 bone marrow: 160.6 -LAMA2 LAMM ENSG00000196569 Laminin, alpha 2 6 128883141-129516569 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB040310, CAB078182 Supported Tissue enhanced 0 placenta: 148.7 ovary: 49.3 -PFN3 ENSG00000196570 Profilin 3 5 177400107-177400636 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 22 kidney: 1.1;testis: 3.2 epididymis: 0.0 -PLXNB2 KIAA0315, MM1, PLEXB2 ENSG00000196576 Plexin B2 22 50274979-50307627 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003100 Uncertain Expressed in all spleen: 123.1 -OR5AC2 HSA1 ENSG00000196578 Olfactory receptor, family 5, subfamily AC, member 2 3 98087173-98088102 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.5 -AJAP1 MOT8, SHREW-1, SHREW1 ENSG00000196581 Adherens junctions associated protein 1 1 4654732-4792534 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 11.3;ovary: 6.0 seminal vesicle: 3.2 -XRCC2 ENSG00000196584 X-ray repair complementing defective repair in Chinese hamster cells 2 7 152644779-152676165 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065153 Approved Nucleoplasm
Vesicles Mixed testis: 3.8 -MYO6 DFNA22, DFNB37, KIAA0389 ENSG00000196586 Myosin VI 6 75749192-75919537 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010762, HPA035483 Approved Supported Nucleoplasm Mixed parathyroid gland: 84.0 -MKL1 BSAC, KIAA1438, MAL, MRTF-A ENSG00000196588 Megakaryoblastic leukemia (translocation) 1 22 40410281-40636702 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030782 Approved Supported Nucleoplasm
Cytosol Expressed in all bone marrow: 51.3 -HDAC2 RPD3, YAF1 ENSG00000196591 Histone deacetylase 2 6 113933028-114011308 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005054, HPA011727 Supported Validated Nucleus Expressed in all testis: 142.0 -ZNF782 FLJ16636 ENSG00000196597 Zinc finger protein 782 9 96816472-96875623 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011013 Approved Approved Nucleus
Mitochondria Mixed testis: 10.3 -SLC22A25 HIMTP, MGC120420, UST6 ENSG00000196600 Solute carrier family 22, member 25 11 63163776-63229652 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039390 Uncertain Tissue enriched 57 liver: 5.7 epididymis: 0.0 -POTEF A26C1B, POTE2alpha, POTEACTIN ENSG00000196604 POTE ankyrin domain family, member F 2 130073535-130129222 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041264, HPA041271, HPA042822, HPA043260 Uncertain Tissue enriched 5 testis: 2.2 prostate: 0.4 -ZNF846 ENSG00000196605 Zinc finger protein 846 19 9751993-9793180 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA034617, HPA034618 Approved Approved Actin filaments Mixed seminal vesicle: 26.0 -MMP1 CLG ENSG00000196611 Matrix metallopeptidase 1 11 102789920-102798160 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004920 Supported Vesicles Tissue enhanced 0 appendix: 39.7;gallbladder: 126.6 urinary bladder: 30.2 -ADH1B ADH2 ENSG00000196616 Alcohol dehydrogenase 1B (class I), beta polypeptide 4 99304964-99321401 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047814, HPA060902 Supported Approved Plasma membrane
Cytosol Group enriched 6 adipose tissue: 1534.1;liver: 2889.4 lung: 371.7 -UGT2B15 UGT2B8 ENSG00000196620 UDP glucuronosyltransferase 2 family, polypeptide B15 4 68537413-68670628 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045108 Approved Group enriched 6 colon: 23.8;duodenum: 30.6;gallbladder: 114.5;liver: 108.6;small intestine: 33.9 stomach: 10.2 -TCF4 bHLHb19, E2-2, ITF2, SEF2-1B ENSG00000196628 Transcription factor 4 18 55222331-55664787 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB020722, HPA025958 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 90.8 -WNK3 PRKWNK3 ENSG00000196632 WNK lysine deficient protein kinase 3 X 54192823-54358642 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077678 Approved Vesicles Group enriched 6 epididymis: 14.1;testis: 18.6 ovary: 2.6 -SDHAF3 ACN9, DC11, Sdh7 ENSG00000196636 Succinate dehydrogenase complex assembly factor 3 7 97116590-97181763 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020523 Approved Approved Microtubules
Mitochondria Expressed in all testis: 15.1 -HRH1 ENSG00000196639 Histamine receptor H1 3 11137093-11263557 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA029740 Uncertain Supported Plasma membrane
Cytosol Mixed cerebral cortex: 12.4 -RABL6 bA216L13.9, C9orf86, FLJ10101, FLJ13045, Parf, pp8875, RBEL1 ENSG00000196642 RAB, member RAS oncogene family-like 6 9 136807943-136957733 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044037, HPA050638 Uncertain Uncertain Nucleus
Centrosome
Cytosol Expressed in all cerebral cortex: 47.0 -ZNF136 pHZ-20 ENSG00000196646 Zinc finger protein 136 19 12163064-12189881 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA054120 Approved Nucleoli Mixed thyroid gland: 14.5 -ZKSCAN5 ZFP95, ZNF914, ZSCAN37 ENSG00000196652 Zinc finger with KRAB and SCAN domains 5 7 99504651-99534700 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA003201 Uncertain Approved Intermediate filaments Mixed testis: 14.9 -ZNF502 FLJ12515, FLJ14855 ENSG00000196653 Zinc finger protein 502 3 44712643-44723831 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA024761, HPA029557 Uncertain Mixed testis: 5.0 -TRAPPC4 PTD009, SBDN, TRS23 ENSG00000196655 Trafficking protein particle complex 4 11 119018432-119025454 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039752, HPA041371 Approved Approved Cytosol Expressed in all testis: 14.8 -TTC30B fleer, FLJ30990, IFT70B ENSG00000196659 Tetratricopeptide repeat domain 30B 2 177548998-177553014 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051714, HPA052100, HPA052487 Supported Approved Nucleus
Centrosome Mixed fallopian tube: 15.5 -SLC30A10 DKFZp547M236, ZnT-10, ZNT8, ZRC1 ENSG00000196660 Solute carrier family 30, member 10 1 219685427-219958647 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017989 Uncertain Tissue enhanced 0 duodenum: 2.2;liver: 2.3 testis: 1.1 -OR8B3 ENSG00000196661 Olfactory receptor, family 8, subfamily B, member 3 11 124396382-124397368 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.5 -TECPR2 KIAA0329 ENSG00000196663 Tectonin beta-propeller repeat containing 2 14 102362963-102502481 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000658 Approved Approved Nucleus Mixed cerebral cortex: 21.5 -TLR7 ENSG00000196664 Toll-like receptor 7 X 12867083-12890380 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA059613 Supported Mixed placenta: 9.1 -FAM180B LOC399888 ENSG00000196666 Family with sequence similarity 180, member B 11 47586693-47589194 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA029408 Uncertain Tissue enhanced 0 breast: 6.9 skin: 4.4 -ZFP62 FLJ34231, ZET, ZNF755 ENSG00000196670 ZFP62 zinc finger protein 5 180847611-180861285 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048629 Approved Approved Nucleoplasm
Actin filaments Expressed in all thyroid gland: 39.5 -ERI2 EXOD1, KIAA1504, MGC16943, ZGRF5 ENSG00000196678 ERI1 exoribonuclease family member 2 16 20780193-20900349 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035384, HPA035385 Uncertain Supported Nucleus
Golgi apparatus Expressed in all testis: 22.9 -TOMM7 ENSG00000196683 Translocase of outer mitochondrial membrane 7 homolog (yeast) 7 22812628-22822852 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 673.7 -HSH2D ALX, FLJ14886, HSH2 ENSG00000196684 Hematopoietic SH2 domain containing 19 16134028-16158575 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036616 Approved Plasma membrane
Focal adhesion sites
Cytosol Mixed tonsil: 34.1 -TRPV1 VR1 ENSG00000196689 Transient receptor potential cation channel, subfamily V, member 1 17 3565444-3609411 FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Mixed duodenum: 8.0 -ZNF33B KOX2, KOX31, ZNF11B ENSG00000196693 Zinc finger protein 33B 10 42574185-42638568 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005538, HPA056638 Approved Uncertain Nucleoli
Endoplasmic reticulum Expressed in all fallopian tube: 31.9 -ZNF512B GM632, MGC149845, MGC149846 ENSG00000196700 Zinc finger protein 512B 20 63956702-64048758 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006688 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 17.7 -AMZ2 ENSG00000196704 Archaelysin family metallopeptidase 2 17 68247574-68257164 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023299, HPA052406 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all testis: 355.4 -ZNF431 KIAA1969 ENSG00000196705 Zinc finger protein 431 19 21142024-21196053 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA059135 Uncertain Mixed ovary: 26.7 -FAM150A UNQ9433 ENSG00000196711 Family with sequence similarity 150, member A 8 52534037-52565507 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027368 Uncertain Tissue enhanced 0 gallbladder: 3.5;thyroid gland: 3.7 cervix: 1.7 -NF1 ENSG00000196712 Neurofibromin 1 17 31094927-31382116 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045502 Uncertain Approved Mitochondria Expressed in all parathyroid gland: 31.9 -VKORC1L1 ENSG00000196715 Vitamin K epoxide reductase complex, subunit 1-like 1 7 65873267-65959563 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053954 Approved Supported Endoplasmic reticulum Expressed in all adipose tissue: 57.3 -ZNF418 FLJ31551, KIAA1956 ENSG00000196724 Zinc finger protein 418 19 57921884-57935393 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA043800, HPA053762, HPA072145 Approved Uncertain Nucleus Mixed parathyroid gland: 14.5 -DAPK1 DAPK ENSG00000196730 Death-associated protein kinase 1 9 87497228-87708633 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037302, HPA040472, HPA048436 Approved Supported Centrosome Mixed lung: 56.3 -LCE1B LEP2, SPRL2A ENSG00000196734 Late cornified envelope 1B 1 152811971-152813109 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 9 skin: 186.3 breast: 19.8 -HLA-DQA1 CELIAC1, HLA-DQA ENSG00000196735 Major histocompatibility complex, class II, DQ alpha 1 6 32628179-32647062 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012315 Supported Tissue enhanced 0 lung: 505.9 lymph node: 346.2 -COL27A1 FLJ11895, KIAA1870, MGC11337 ENSG00000196739 Collagen, type XXVII, alpha 1 9 114155560-114312511 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021884, HPA048471 Uncertain Mixed endometrium: 39.7 -GM2A SAP-3 ENSG00000196743 GM2 ganglioside activator 5 151212150-151270440 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008063 Supported Expressed in all skin: 89.8 -HIST1H2AI H2A/c, H2AFC ENSG00000196747 Histone cluster 1, H2ai 6 27808199-27808701 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Mixed bone marrow: 3.1 -CLPSL2 C6orf126, dJ510O8.5, UNQ3045 ENSG00000196748 Colipase-like 2 6 35776594-35779552 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 699 epididymis: 698.5 seminal vesicle: 0.9 -S100A2 CAN19, S100L ENSG00000196754 S100 calcium binding protein A2 1 153561108-153567890 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002600, CAB047340, HPA062451 Supported Supported Nucleus
Nucleoli
Plasma membrane
Cytosol Tissue enhanced 0 esophagus: 1487.6;tonsil: 385.6 urinary bladder: 368.6 -ZNF700 DKFZp434I1610 ENSG00000196757 Zinc finger protein 700 19 11925068-11950773 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047845 Uncertain Uncertain Nucleus Expressed in all skin: 19.1 -POU3F4 BRN4, DFN3, DFNX2, OTF9 ENSG00000196767 POU class 3 homeobox 4 X 83508250-83512127 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA031984 Uncertain Tissue enriched 11 cerebral cortex: 8.0 kidney: 0.7 -OR14A16 OR5AT1 ENSG00000196772 Olfactory receptor, family 14, subfamily A, member 16 1 247814800-247815729 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.1 -CD47 IAP, MER6, OA3 ENSG00000196776 CD47 molecule 3 108043298-108091025 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016055, HPA044659 Approved Supported Golgi apparatus
Vesicles
Plasma membrane Expressed in all lung: 204.9 -OR52K1 ENSG00000196778 Olfactory receptor, family 52, subfamily K, member 1 11 4488879-4489908 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected appendix: 0.1 -TLE1 ESG, ESG1, GRG1 ENSG00000196781 Transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 9 81583683-81689305 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011482, HPA071396 Supported Supported Nucleoplasm Expressed in all endometrium: 52.1 -MAML3 CAGH3, GDN, KIAA1816, MAM2, TNRC3 ENSG00000196782 Mastermind-like transcriptional coactivator 3 4 139716753-140154184 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA037717 Approved Supported Nuclear speckles Mixed endometrium: 10.8 -HIST1H2AG H2A.1b, H2A/p, H2AFP, pH2A/f ENSG00000196787 Histone cluster 1, H2ag 6 27133042-27135291 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enhanced 0 testis: 5.7 breast: 3.7 -STRN3 SG2NA ENSG00000196792 Striatin, calmodulin binding protein 3 14 30893799-31026401 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003392, HPA004636, CAB069925 Approved Supported Nucleoplasm
Actin filaments
Cytosol Expressed in all testis: 44.4 -ZNF239 HOK-2, MOK2 ENSG00000196793 Zinc finger protein 239 10 43556344-43574618 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA030843, HPA046679 Uncertain Approved Nucleus
Nuclear bodies Mixed testis: 14.6 -SPINK14 SPINK5L2 ENSG00000196800 Serine peptidase inhibitor, Kazal type 14 (putative) 5 148169733-148175398 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 breast: 1.0;rectum: 1.2 cervix: 0.7 -SPRR2B ENSG00000196805 Small proline-rich protein 2B 1 153070224-153070840 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 18 esophagus: 30.4;skin: 17.1;testis: 8.2;tonsil: 14.7 ovary: 0.9 -CHRNG ACHRG ENSG00000196811 Cholinergic receptor, nicotinic, gamma (muscle) 2 232539727-232546403 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 19 skeletal muscle: 8.2 prostate: 0.4 -ZSCAN16 dJ265C24.3, FLJ22191, ZNF392, ZNF435 ENSG00000196812 Zinc finger and SCAN domain containing 16 6 28124560-28130082 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007290 Supported Approved Nucleus Mixed parathyroid gland: 12.7 -MVB12B C9orf28, FAM125B, FLJ00001 ENSG00000196814 Multivesicular body subunit 12B 9 126326849-126507041 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043683, HPA049383 Uncertain Approved Golgi apparatus
Vesicles Mixed cerebral cortex: 36.6 -C6orf106 dJ391O22.4, FLJ22195 ENSG00000196821 Chromosome 6 open reading frame 106 6 34587288-34696859 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034489, HPA034490 Approved Approved Nuclear speckles Expressed in all testis: 125.3 -CTD-2192J16.17 ENSG00000196826 19 12461559-12551474 Predicted intracellular proteins No evidence No evidence Not detected endometrium: 0.7 -OR11G2 ENSG00000196832 Olfactory receptor, family 11, subfamily G, member 2 14 20197336-20198446 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Not detected epididymis: 0.0 -POTEI POTE2beta ENSG00000196834 POTE ankyrin domain family, member I 2 130459455-130509666 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA041264, HPA041271, HPA042822, HPA043260 Uncertain Group enriched 13 prostate: 18.0;testis: 10.4 breast: 1.1 -ADA ENSG00000196839 Adenosine deaminase 20 44619522-44652233 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001399, CAB004307, HPA023884 Supported Tissue enriched 14 duodenum: 501.3 lymph node: 37.0 -ARID5A MRF-1, RP11-363D14 ENSG00000196843 AT rich interactive domain 5A (MRF1-like) 2 96536743-96552638 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA002860, HPA023879 Approved Supported Nucleus
Nucleoli Expressed in all appendix: 26.1 -PATE2 C11orf38, LVLF3112, PATE-M, UNQ3112 ENSG00000196844 Prostate and testis expressed 2 11 125776113-125778819 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 11 epididymis: 541.7 seminal vesicle: 50.3 -PPTC7 TA-PP2C ENSG00000196850 PTC7 protein phosphatase homolog 12 110533245-110583320 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039335, HPA040614 Approved Approved Plasma membrane
Cytosol Expressed in all parathyroid gland: 33.7 -KRT39 KA35 ENSG00000196859 Keratin 39, type I 17 40958417-40966892 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected epididymis: 0.0 -TOMM20L UNQ9438 ENSG00000196860 Translocase of outer mitochondrial membrane 20 homolog (yeast)-like 14 58395916-58408701 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044997 Uncertain Tissue enriched 10 testis: 13.1 parathyroid gland: 1.3 -RGPD4 DKFZp686P0288, RGP4 ENSG00000196862 RANBP2-like and GRIP domain containing 4 2 107826937-107890841 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049497, HPA051675, HPA067564 Uncertain Uncertain Nuclear membrane
Vesicles Tissue enriched 58 testis: 5.7 epididymis: 0.0 -NHLRC2 DKFZp779F115, FLJ20147, FLJ25621, FLJ33312, MGC45492 ENSG00000196865 NHL repeat containing 2 10 113854661-113917194 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038493, HPA057564 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 18.3 -HIST1H2AD H2A.3, H2A/g, H2AFG ENSG00000196866 Histone cluster 1, H2ad 6 26198851-26199243 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enhanced 0 bone marrow: 2.2;prostate: 1.5 esophagus: 1.1 -ZFP28 KIAA1431, mkr5 ENSG00000196867 ZFP28 zinc finger protein 19 56538948-56556810 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA028879 Uncertain Approved Nucleoplasm
Cytosol Mixed ovary: 13.0 -KIAA1211L C2orf55, MGC42367 ENSG00000196872 KIAA1211-like 2 98793846-98936259 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051082, HPA061678 Uncertain Approved Microtubules
Cytokinetic bridge
Centrosome Tissue enhanced 0 cerebral cortex: 36.9;epididymis: 38.1 fallopian tube: 35.8 -CBWD3 bA561O23.1 ENSG00000196873 COBW domain containing 3 9 68232003-68300015 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042759, HPA042813 Uncertain Approved Plasma membrane Expressed in all appendix: 25.9 -SCN8A CerIII, MED, NaCh6, Nav1.6, PN4 ENSG00000196876 Sodium channel, voltage gated, type VIII alpha subunit 12 51590266-51812864 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022169 Supported Vesicles
Cell Junctions Tissue enriched 6 cerebral cortex: 22.1 testis: 3.5 -LAMB3 BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa ENSG00000196878 Laminin, beta 3 1 209614870-209652466 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008069, CAB078183 Approved Approved Nucleoli
Mitochondria Mixed stomach: 70.1 -HIST3H2BB ENSG00000196890 Histone cluster 3, H2bb 1 228458107-228460470 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 fallopian tube: 2.6 skin: 1.8 -TEX43 C5orf48, FLJ27505, MGC163367, MGC163369, Tseg7 ENSG00000196900 Testis expressed 43 5 126631722-126636287 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 13 testis: 35.2 rectum: 2.7 -KPNA5 IPOA6, SRP6 ENSG00000196911 Karyopherin alpha 5 (importin alpha 6) 6 116681187-116741866 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026464, HPA054037 Supported Supported Cytosol Tissue enhanced 0 testis: 83.1 ovary: 23.5 -ANKRD36B FLJ21281, KIAA1641 ENSG00000196912 Ankyrin repeat domain 36B 2 97492663-97589965 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051757, HPA057661 Approved Nucleus
Cytosol Mixed testis: 13.1 -ARHGEF12 KIAA0382, LARG ENSG00000196914 Rho guanine nucleotide exchange factor (GEF) 12 11 120336914-120489936 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018911, CAB025581 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 143.2 -HCAR1 FKSG80, GPR104, GPR81, HCA1, LACR1, TA-GPCR ENSG00000196917 Hydroxycarboxylic acid receptor 1 12 122726076-122730843 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 7 parathyroid gland: 113.5 breast: 15.1 -PDLIM7 ENIGMA ENSG00000196923 PDZ and LIM domain 7 (enigma) 5 177483394-177497606 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018794, HPA048815 Approved Validated Actin filaments
Focal adhesion sites Expressed in all seminal vesicle: 285.6 -FLNA ABP-280, FLN, FLN1, OPD1, OPD2 ENSG00000196924 Filamin A, alpha X 154348524-154374638 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000356, HPA000368, HPA001016, HPA001115, HPA002925 Supported Approved Validated Plasma membrane
Actin filaments
Cytosol Expressed in all smooth muscle: 1037.9 -TMEM26 Em:AC068892.1, MGC35010 ENSG00000196932 Transmembrane protein 26 10 61406643-61453450 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 spleen: 12.0 endometrium: 6.7 -SRGAP1 ARHGAP13, KIAA1304 ENSG00000196935 SLIT-ROBO Rho GTPase activating protein 1 12 63844293-64162221 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052416 Uncertain Approved Nuclear speckles Mixed parathyroid gland: 13.0 -OR2L8 ENSG00000196936 Olfactory receptor, family 2, subfamily L, member 8 (gene/pseudogene) 1 247948858-247949796 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -FAM3C GS3876, ILEI ENSG00000196937 Family with sequence similarity 3, member C 7 121348851-121396364 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043376, HPA050548 Supported Validated Golgi apparatus Expressed in all thyroid gland: 180.6 -NOP9 C14orf21 ENSG00000196943 NOP9 nucleolar protein 14 24299862-24309124 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000850 Approved Nucleus
Nucleoli
Cytosol Expressed in all parathyroid gland: 28.8 -OR2T4 OR2T4Q ENSG00000196944 Olfactory receptor, family 2, subfamily T, member 4 1 248361581-248362627 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected prostate: 0.1 -ZNF705A FLJ16353 ENSG00000196946 Zinc finger protein 705A 12 8138137-8188537 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed cerebral cortex: 9.1 -SLC39A10 DKFZp564L2123, FLJ90515, KIAA1265 ENSG00000196950 Solute carrier family 39 (zinc transporter), member 10 2 195575977-195737702 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036512, HPA036513, HPA066087 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 78.0;thyroid gland: 79.0 prostate: 27.6 -CASP4 ICE(rel)II, ICH-2, TX ENSG00000196954 Caspase 4, apoptosis-related cysteine peptidase 11 104942866-104969436 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027588, CAB037167 Approved Approved Plasma membrane
Cytosol Expressed in all placenta: 71.5 -AP2A1 ADTAA, CLAPA1 ENSG00000196961 Adaptor-related protein complex 2, alpha 1 subunit 19 49766968-49807113 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004306 Approved Supported Vesicles Expressed in all testis: 104.1 -ZNF585A FLJ23765 ENSG00000196967 Zinc finger protein 585A 19 37106734-37172741 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all thyroid gland: 17.7 -FUT11 MGC33202 ENSG00000196968 Fucosyltransferase 11 (alpha (1,3) fucosyltransferase) 10 73772291-73780251 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014033 Approved Approved Nuclear membrane
Golgi apparatus Mixed placenta: 24.8 -SMIM10L2B LINC00087, NCRNA00087, RP11-85L21.2 ENSG00000196972 Small integral membrane protein 10 like 2B X 135095028-135098634 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 cerebral cortex: 24.2 heart muscle: 8.5 -ANXA4 ANX4 ENSG00000196975 Annexin A4 2 69644425-69827100 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005076, HPA007393, CAB017560 Approved Approved Cytosol Expressed in all gallbladder: 884.9 -LAGE3 CVG5, DXS9879E, DXS9951E, ESO3, ITBA2 ENSG00000196976 L antigen family, member 3 X 154477769-154479257 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036122, HPA036123 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all cerebral cortex: 38.9 -WDR5B FLJ11287 ENSG00000196981 WD repeat domain 5B 3 122412332-122416051 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042994 Approved Mixed epididymis: 13.3 -FAM163B C9orf166 ENSG00000196990 Family with sequence similarity 163, member B 9 133578415-133586197 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA067336 Approved Approved Nuclear bodies
Plasma membrane
Cytosol Tissue enriched 6 cerebral cortex: 103.9 adrenal gland: 16.5 -NPIPB9 ENSG00000196993 Nuclear pore complex interacting protein family, member B9 16 28751787-28772807 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA011188, HPA053611 Approved Approved Nucleoplasm Tissue enriched 8 testis: 14.7 skin: 1.9 -WDR45 JM5, NBIA5, WDRX1, WIPI4 ENSG00000196998 WD repeat domain 45 X 49071470-49101170 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027562 Uncertain Approved Nucleoli Expressed in all epididymis: 133.5 -METTL9 DREV1 ENSG00000197006 Methyltransferase like 9 16 21597218-21657473 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA053588, HPA056347 Uncertain Approved Nucleus
Cell Junctions
Cytosol Expressed in all kidney: 182.7 -ZNF138 pHZ-32 ENSG00000197008 Zinc finger protein 138 7 64794388-64833681 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA077435 Uncertain Cytosol Mixed cerebral cortex: 9.2 -ZNF429 ENSG00000197013 Zinc finger protein 429 19 21496682-21556270 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA004139 Approved Nucleus Mixed thyroid gland: 17.1 -ZNF470 CZF-1, FLJ26175 ENSG00000197016 Zinc finger protein 470 19 56567511-56588911 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA029000 Uncertain Supported Nucleoplasm
Nuclear bodies Mixed cerebral cortex: 5.8 -SERTAD1 SEI1, TRIP-Br1 ENSG00000197019 SERTA domain containing 1 19 40421592-40426025 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA063323 Approved Nucleoplasm
Golgi apparatus Expressed in all gallbladder: 19.7 -ZNF100 ENSG00000197020 Zinc finger protein 100 19 21722766-21767628 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA059135 Uncertain Mixed testis: 11.9 -CXorf40B ENSG00000197021 Chromosome X open reading frame 40B X 149929527-149938811 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060897 Approved Expressed in all adrenal gland: 79.8 -ZNF398 KIAA1339, P51, P71, ZER6 ENSG00000197024 Zinc finger protein 398 7 149126416-149182802 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA071533 Approved Nucleoplasm
Mitochondria Expressed in all testis: 16.0 -ZSCAN25 FLJ32468, ZNF498 ENSG00000197037 Zinc finger and SCAN domain containing 25 7 99616946-99632407 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055127, HPA057173 Uncertain Approved Nucleus
Nucleoli fibrillar center Mixed parathyroid gland: 9.8 -ANXA6 ANX6 ENSG00000197043 Annexin A6 5 151100712-151157882 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002462, CAB005077, HPA009650 Supported Approved Nuclear speckles Expressed in all smooth muscle: 426.1 -ZNF441 FLJ38637 ENSG00000197044 Zinc finger protein 441 19 11767000-11784078 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA063338 Approved Nuclear speckles Mixed thyroid gland: 12.1 -GMFB GMF ENSG00000197045 Glia maturation factor, beta 14 54474484-54489196 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002954 Approved Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all cerebral cortex: 109.0 -SIGLEC15 CD33L3, HsT1361 ENSG00000197046 Sialic acid binding Ig-like lectin 15 18 45825512-45844080 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA053509 Supported Nucleoplasm
Golgi apparatus Not detected spleen: 0.6 -ZNF420 FLJ32191 ENSG00000197050 Zinc finger protein 420 19 37007857-37130314 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053022, HPA059675 Approved Approved Nucleoplasm Mixed testis: 18.4 -ZNF763 ZNF440L ENSG00000197054 Zinc finger protein 763 19 11965037-11980381 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047845 Uncertain Uncertain Nucleus Mixed parathyroid gland: 11.4 -ZMYM1 FLJ23151, MYM ENSG00000197056 Zinc finger, MYM-type 1 1 35059786-35115859 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA064019 Approved Microtubule organizing center Mixed testis: 6.9 -DTHD1 FLJ16686 ENSG00000197057 Death domain containing 1 4 36281622-36345756 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 fallopian tube: 22.8 lung: 5.3 -HIST1H4C dJ221C16.1, H4/g, H4FG ENSG00000197061 Histone cluster 1, H4c 6 26103876-26104310 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Mixed bone marrow: 2.9 -ZSCAN26 SRE-ZBP, ZNF187 ENSG00000197062 Zinc finger and SCAN domain containing 26 6 28267010-28278224 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027521 Validated Nucleus
Nucleoli Expressed in all ovary: 40.3 -MAFG MGC13090, MGC20149 ENSG00000197063 V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 17 81918270-81927714 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025573 Approved Expressed in all cerebral cortex: 28.3 -ARRDC1 MGC40555 ENSG00000197070 Arrestin domain containing 1 9 137605654-137615360 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA022915, HPA044345 Uncertain Approved Nucleus
Nucleoli Expressed in all stomach: 26.5 -KIAA1671 ENSG00000197077 KIAA1671 22 24952730-25197448 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018135 Approved Approved Microtubules Mixed thyroid gland: 43.6 -KRT35 Ha-5, KRTHA5 ENSG00000197079 Keratin 35, type I 17 41476689-41481140 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 8 skin: 2.2 spleen: 0.2 -IGF2R CD222, CIMPR, M6P-R, MPR1, MPRI ENSG00000197081 Insulin-like growth factor 2 receptor 6 159969099-160113507 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009661, HPA011332 Supported Validated Golgi apparatus
Vesicles Expressed in all parathyroid gland: 49.5 -LCE1C LEP3 ENSG00000197084 Late cornified envelope 1C 1 152804835-152806628 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 11 skin: 514.5 breast: 44.9 -GAL3ST4 FLJ12116 ENSG00000197093 Galactose-3-O-sulfotransferase 4 7 100159244-100168750 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038137, HPA038138 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced 0 skin: 32.6 smooth muscle: 14.6 -DYNC1H1 CMT2O, DHC1, DNCH1, Dnchc1, DNCL, DNECL, HL-3, p22 ENSG00000197102 Dynein, cytoplasmic 1, heavy chain 1 14 101964528-102050792 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003742, CAB010443 Supported Supported Centrosome
Cytosol Expressed in all cerebral cortex: 80.8 -SLC6A17 ENSG00000197106 Solute carrier family 6 (neutral amino acid transporter), member 17 1 110150486-110202202 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007663, HPA008044 Approved Approved Nucleus
Golgi apparatus Tissue enriched 10 cerebral cortex: 75.6 adrenal gland: 7.9 -IFNL3 IL-28B, IL28B, IL28C ENSG00000197110 Interferon, lambda 3 19 39243553-39245129 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.2 -PCBP2 hnRNP-E2, HNRNPE2, HNRPE2 ENSG00000197111 Poly(rC) binding protein 2 12 53452102-53481162 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038356 Uncertain Supported Nucleoplasm
Cytosol Expressed in all thyroid gland: 742.9 -ZGPAT dJ583P15.3, FLJ14972, GPATC6, GPATCH6, KIAA1847, MGC44880, ZC3H9, ZC3HDC9, ZIP ENSG00000197114 Zinc finger, CCCH-type with G patch domain 20 63707465-63736142 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056705 Supported Nucleus
Plasma membrane Expressed in all liver: 26.9 -SLC25A29 C14orf69, FLJ38975 ENSG00000197119 Solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 14 100291111-100306547 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030781 Uncertain Expressed in all thyroid gland: 158.5 -PGAP1 Bst1, FLJ12377, SPG67 ENSG00000197121 Post-GPI attachment to proteins 1 2 196833004-196927796 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069704 Uncertain Mixed skin: 14.7 -SRC ASV, c-src, SRC1 ENSG00000197122 SRC proto-oncogene, non-receptor tyrosine kinase 20 37344685-37406050 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004023, HPA030875 Approved Validated Plasma membrane
Cytosol Mixed small intestine: 43.7 -ZNF679 MGC42415 ENSG00000197123 Zinc finger protein 679 7 64228474-64266931 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 18 testis: 1.8 epididymis: 0.0 -ZNF682 BC39498_3 ENSG00000197124 Zinc finger protein 682 19 19997058-20039506 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055998 Uncertain Uncertain Golgi apparatus Mixed thyroid gland: 13.3 -OR8B8 TPCR85 ENSG00000197125 Olfactory receptor, family 8, subfamily B, member 8 11 124440126-124441158 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -ZNF772 DKFZp686I1569 ENSG00000197128 Zinc finger protein 772 19 57466663-57477570 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA031312 Uncertain Approved Cytosol Mixed parathyroid gland: 19.7 -ZNF257 BMZF-4 ENSG00000197134 Zinc finger protein 257 19 22052452-22091480 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed testis: 4.3 -PCNXL3 FLJ22427 ENSG00000197136 Pecanex-like 3 (Drosophila) 11 65615773-65637439 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018084 Uncertain Approved Cytosol Mixed testis: 17.3 -ADAM32 ENSG00000197140 ADAM metallopeptidase domain 32 8 39106990-39284911 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA044156, HPA062151 Approved Approved Nucleus
Vesicles Tissue enriched 31 testis: 28.7 epididymis: 0.9 -ACSL5 ACS2, ACS5, FACL5 ENSG00000197142 Acyl-CoA synthetase long-chain family member 5 10 112374018-112428380 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007162, CAB062546 Supported Supported Nucleus
Mitochondria Expressed in all small intestine: 469.9 -LRRC8B KIAA0231, TA-LRRP ENSG00000197147 Leucine rich repeat containing 8 family, member B 1 89524836-89597864 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017950 Uncertain Approved Nuclear speckles Tissue enhanced 0 cerebral cortex: 38.3 testis: 30.6 -ABCB8 EST328128, M-ABC1, MABC1 ENSG00000197150 ATP-binding cassette, sub-family B (MDR/TAP), member 8 7 151028422-151047782 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045187 Approved Supported Nucleus
Mitochondria Expressed in all thyroid gland: 17.0 -HIST1H3J H3/j, H3FJ ENSG00000197153 Histone cluster 1, H3j 6 27890382-27893106 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Tissue enhanced 0 lymph node: 1.5 testis: 0.8 -SND1 p100, TDRD11 ENSG00000197157 Staphylococcal nuclease and tudor domain containing 1 7 127652180-128092609 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002529, HPA002632, CAB019323 Supported Validated Cytosol Expressed in all placenta: 121.5 -ZNF785 FLJ32130 ENSG00000197162 Zinc finger protein 785 16 30573740-30585771 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA030510 Approved Nucleoplasm
Plasma membrane Expressed in all endometrium: 11.8 -SULT1A2 HAST4, STP2 ENSG00000197165 Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 16 28591943-28597109 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049500, HPA051051 Supported Tissue enhanced 0 duodenum: 50.6;small intestine: 50.2 liver: 20.9 -NEK5 ENSG00000197168 NIMA-related kinase 5 13 52033611-52129078 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035565, HPA041399 Supported Group enriched 8 fallopian tube: 12.1;testis: 18.7 lung: 1.9 -PSMD12 p55, Rpn5 ENSG00000197170 Proteasome 26S subunit, non-ATPase 12 17 67337916-67366627 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023119 Approved Approved Nucleus
Microtubules
Cytosol Expressed in all testis: 26.1 -MAGEA6 CT1.6, MAGE6 ENSG00000197172 Melanoma antigen family A6 X 152766136-152769747 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 22 testis: 10.9 endometrium: 0.4 -ADGRA1 GPR123, KIAA1828 ENSG00000197177 Adhesion G protein-coupled receptor A1 10 133070929-133131675 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042773 Approved Tissue enhanced 0 adrenal gland: 4.9;cerebral cortex: 22.5 fallopian tube: 3.1 -PIWIL2 CT80, FLJ10351, HILI, Mili ENSG00000197181 Piwi-like RNA-mediated gene silencing 2 8 22275297-22357563 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 8 testis: 53.2 duodenum: 6.2 -NOL4L C20orf112, C20orf113, dJ1184F4.2, dJ1184F4.4, DKFZP566G1424 ENSG00000197183 Nucleolar protein 4-like 20 32443059-32585074 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041768, HPA043600 Supported Validated Nucleoplasm Tissue enhanced 0 testis: 61.6 small intestine: 22.5 -CYSRT1 C9orf169, MGC59937 ENSG00000197191 Cysteine-rich tail protein 1 9 137224635-137226311 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA021883, HPA021886 Approved Approved Nuclear speckles
Vesicles
Midbody Tissue enhanced 0 esophagus: 45.7;skin: 12.3 tonsil: 6.7 -SLC22A4 MGC34546, OCTN1 ENSG00000197208 Solute carrier family 22 (organic cation/zwitterion transporter), member 4 5 132294443-132344206 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB015468, HPA036973 Approved Uncertain Nucleoplasm
Cytosol Tissue enhanced 0 fallopian tube: 18.6 bone marrow: 13.2 -ZSCAN5B ZNF371, ZNF495B ENSG00000197213 Zinc finger and SCAN domain containing 5B 19 56189570-56197920 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level No evidence HPA043123, HPA046836, HPA059494, HPA060667 Uncertain Uncertain Nuclear speckles Tissue enriched 22 testis: 2.7 fallopian tube: 0.1 -ENTPD4 KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase ENSG00000197217 Ectonucleoside triphosphate diphosphohydrolase 4 8 23385783-23457695 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA017655 Supported Supported Vesicles Expressed in all parathyroid gland: 46.4 -C1D LRP1, Rrp47, SUN-CoR, SUNCOR ENSG00000197223 C1D nuclear receptor corepressor 2 68041130-68110948 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037413, HPA037588 Approved Validated Nucleus
Nucleoli Expressed in all thyroid gland: 51.7 -TBC1D9B KIAA0676 ENSG00000197226 TBC1 domain family, member 9B (with GRAM domain) 5 179862066-179907859 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038350 Approved Approved Nucleus
Nucleoli fibrillar center
Plasma membrane Expressed in all cerebral cortex: 60.9 -OR1J2 OR1J3, OR1J5, OST044 ENSG00000197233 Olfactory receptor, family 1, subfamily J, member 2 9 122510802-122511743 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected urinary bladder: 0.2 -HIST1H4J H4/e, H4F2iv, H4FE ENSG00000197238 Histone cluster 1, H4j 6 27824108-27824480 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Mixed bone marrow: 15.2 -SLC2A7 GLUT7 ENSG00000197241 Solute carrier family 2 (facilitated glucose transporter), member 7 1 9003300-9026345 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039931 Uncertain Group enriched 9 duodenum: 3.1;small intestine: 3.1 epididymis: 0.3 -FAM110D FLJ14050, GRRP1 ENSG00000197245 Family with sequence similarity 110, member D 1 26159020-26163962 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA013664 Approved Mixed adipose tissue: 4.8 -SERPINA1 A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1 ENSG00000197249 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 14 94376747-94390693 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000927, HPA001292, CAB013211, CAB016648, CAB073396 Supported Validated Vesicles Tissue enriched 19 liver: 15340.0 lung: 799.2 -TPSB2 ENSG00000197253 Tryptase beta 2 (gene/pseudogene) 16 1227272-1230184 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049153, HPA049554 Supported Tissue enhanced 0 gallbladder: 157.9 lung: 117.7 -KANK2 ANKRD25, KIAA1518, MXRA3 ENSG00000197256 KN motif and ankyrin repeat domains 2 19 11164267-11197791 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015643 Approved Expressed in all endometrium: 438.4 -C6orf141 MGC46457 ENSG00000197261 Chromosome 6 open reading frame 141 6 49550646-49561907 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036199 Uncertain Approved Nuclear membrane Tissue enhanced 0 gallbladder: 9.3 duodenum: 6.4 -OR8D2 ENSG00000197263 Olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene) 11 124319262-124320197 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -GTF2E2 FE, TF2E2, TFIIE-B ENSG00000197265 General transcription factor IIE, polypeptide 2, beta 34kDa 8 30578318-30658251 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004816, CAB009603, HPA025065 Approved Validated Nucleoplasm
Cytosol Expressed in all testis: 52.5 -IL27 IL-27, IL-27A, IL27A, IL27p28, IL30, MGC71873, p28 ENSG00000197272 Interleukin 27 16 28499362-28512051 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB024722 Approved Tissue enhanced 0 liver: 7.9 appendix: 1.7 -GUCA2A GUCA2, STARA ENSG00000197273 Guanylate cyclase activator 2A (guanylin) 1 42162691-42164718 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018215 Supported Group enriched 15 colon: 782.6;rectum: 872.3;small intestine: 1146.4 duodenum: 63.3 -RAD54B RDH54 ENSG00000197275 RAD54 homolog B (S. cerevisiae) 8 94371960-94475109 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007087 Uncertain Mixed fallopian tube: 10.6 -ZNF165 CT53, ZSCAN7 ENSG00000197279 Zinc finger protein 165 6 28080975-28089563 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA007247 Approved Nuclear speckles
Microtubules Tissue enhanced 0 testis: 35.8 epididymis: 7.5 -SYNGAP1 KIAA1938, RASA5, SYNGAP ENSG00000197283 Synaptic Ras GTPase activating protein 1 6 33420070-33457541 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038373, HPA038374 Uncertain Approved Nucleus Mixed cerebral cortex: 28.2 -FITM2 C20orf142, dJ881L22.2, FIT2 ENSG00000197296 Fat storage-inducing transmembrane protein 2 20 44302838-44311169 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 heart muscle: 40.2 parathyroid gland: 23.7 -BLM BS, RECQ2, RECQL3 ENSG00000197299 Bloom syndrome, RecQ helicase-like 15 90717327-90816165 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005689 Approved Supported Nucleus
Cytosol Mixed lymph node: 3.8 -ZNF720 ENSG00000197302 Zinc finger protein 720 16 31713229-31794869 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041570 Uncertain Approved Nucleoplasm
Cytosol Expressed in all testis: 15.4 -OR10D3 HTPCRX09, OR10D3P ENSG00000197309 Olfactory receptor, family 10, subfamily D, member 3 (non-functional) 11 124185216-124186245 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA049991 Uncertain Not detected testis: 0.7 -DDI2 MGC14844 ENSG00000197312 DNA-damage inducible 1 homolog 2 1 15617500-15669044 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043119, HPA043225 Approved Validated Nucleoplasm
Cytosol Expressed in all parathyroid gland: 19.3 -SVIL ENSG00000197321 Supervillin 10 29457338-29736781 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010878, HPA020095, HPA020138 Approved Supported Plasma membrane
Actin filaments
Cytosol Expressed in all skeletal muscle: 279.8 -TRIM33 FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA ENSG00000197323 Tripartite motif containing 33 1 114392777-114511160 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004345 Supported Approved Nucleoplasm
Vesicles Expressed in all testis: 46.0 -LRP10 DKFZP564C1940, LRP9, MGC8675, MST087, MSTP087 ENSG00000197324 Low density lipoprotein receptor-related protein 10 14 22871613-22881580 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000932 Approved Nucleus
Nucleoli Expressed in all esophagus: 180.2 -PELI1 ENSG00000197329 Pellino E3 ubiquitin protein ligase 1 2 64092652-64144454 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA053182 Uncertain Approved Nucleus
Nucleoli
Intermediate filaments Expressed in all bone marrow: 144.1 -ZNF655 VIK, VIK-1 ENSG00000197343 Zinc finger protein 655 7 99558406-99576453 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029534, HPA050750 Uncertain Supported Nucleoplasm
Plasma membrane Expressed in all lymph node: 21.5 -MRPL21 ENSG00000197345 Mitochondrial ribosomal protein L21 11 68891276-68903835 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051657 Approved Approved Nucleoplasm
Mitochondria Expressed in all thyroid gland: 74.9 -LYPD2 LYPDC2, RGTR430, UNQ430 ENSG00000197353 LY6/PLAUR domain containing 2 8 142750150-142752534 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA028599 Uncertain Tissue enhanced 0 esophagus: 99.6;tonsil: 25.0 stomach: 21.6 -UAP1L1 ENSG00000197355 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 9 137077501-137084539 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044356 Approved Approved Intermediate filaments
Cytosol Mixed spleen: 13.5 -ZNF98 F7175, ZNF739 ENSG00000197360 Zinc finger protein 98 19 22391019-22532485 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 ovary: 14.3;testis: 14.2 thyroid gland: 7.8 -FBXL22 Fbl22, FLJ39626 ENSG00000197361 F-box and leucine-rich repeat protein 22 15 63597353-63602428 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047624, HPA054627 Uncertain Uncertain Nucleoli
Cytosol Tissue enhanced 0 endometrium: 45.1;seminal vesicle: 34.9;smooth muscle: 36.2 prostate: 17.4 -ZNF786 DKFZp762I137 ENSG00000197362 Zinc finger protein 786 7 149069643-149090782 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA021518, HPA053459 Uncertain Approved Nucleoplasm
Nuclear speckles Mixed skin: 7.2 -ZNF517 ENSG00000197363 Zinc finger protein 517 8 144798876-144811169 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055337 Approved Nucleoplasm Mixed skin: 7.5 -S100A7L2 s100a7b ENSG00000197364 S100 calcium binding protein A7-like 2 1 153437058-153439949 Predicted intracellular proteins No evidence No evidence No evidence HPA057828 Uncertain Not detected testis: 0.3 -ZNF675 TBZF, TIZ ENSG00000197372 Zinc finger protein 675 19 23525631-23687220 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all testis: 25.0 -SLC22A5 CDSP, OCTN2, SCD ENSG00000197375 Solute carrier family 22 (organic cation/carnitine transporter), member 5 5 132369752-132395614 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063062 Approved Mitochondria Mixed parathyroid gland: 31.4 -OR8S1 ENSG00000197376 Olfactory receptor, family 8, subfamily S, member 1 12 48507354-48529897 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA045595 Uncertain Approved Plasma membrane Not detected breast: 0.1 -DACT3 DAPPER3, MGC15476, RRR1 ENSG00000197380 Dishevelled-binding antagonist of beta-catenin 3 19 46647612-46661138 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043053 Approved Approved Nucleoplasm
Vesicles Mixed smooth muscle: 46.2 -ADARB1 ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1 ENSG00000197381 Adenosine deaminase, RNA-specific, B1 21 45073853-45226560 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018277, HPA029645 Uncertain Supported Nucleoplasm
Cytosol Expressed in all lung: 30.3 -ZNF860 ENSG00000197385 Zinc finger protein 860 3 31981771-31991628 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA063386 Uncertain Approved Nucleus
Nucleoli Mixed prostate: 4.5 -HTT HD, IT15 ENSG00000197386 Huntingtin 4 3074681-3243959 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002756, HPA026114 Supported Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 26.8 -OR6N1 ENSG00000197403 Olfactory receptor, family 6, subfamily N, member 1 1 158765744-158766682 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected bone marrow: 0.6 -C5AR1 C5A, C5AR, C5R1, CD88 ENSG00000197405 Complement component 5a receptor 1 19 47290023-47322066 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB002720, HPA014520 Approved Tissue enhanced 0 appendix: 123.6 adipose tissue: 90.1 -DIO3 TXDI3 ENSG00000197406 Deiodinase, iodothyronine, type III 14 101561351-101563452 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cervix, uterine: 27.7;placenta: 25.2 ovary: 6.2 -CYP2B6 CPB6, CYP2B, CYPIIB6 ENSG00000197408 Cytochrome P450, family 2, subfamily B, polypeptide 6 19 40991299-41018398 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033866, HPA048124, HPA062973 Supported Approved Nucleoplasm
Nuclear membrane
Cytosol Tissue enriched 18 liver: 282.7 kidney: 15.6 -HIST1H3D H3/b, H3FB ENSG00000197409 Histone cluster 1, H3d 6 26196840-26197250 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Tissue enriched 8 bone marrow: 6.5 adrenal gland: 0.8 -DCHS2 CDH27, CDHJ, CDHR7, FLJ20047, PCDH23, PCDHJ ENSG00000197410 Dachsous cadherin-related 2 4 154232037-154491716 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA064159 Uncertain Approved Vesicles
Plasma membrane Mixed endometrium: 4.0 -VEPH1 FLJ12604, KIAA1692 ENSG00000197415 Ventricular zone expressed PH domain-containing 1 3 157259742-157533619 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA026645 Uncertain Approved Nucleus
Nucleoli
Cytosol Tissue enhanced 0 adrenal gland: 26.8;kidney: 28.5;lung: 43.9 epididymis: 21.0 -FABP12 ENSG00000197416 Fatty acid binding protein 12 8 81524981-81531378 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044041 Approved Group enriched 13 esophagus: 4.4;testis: 15.2 lung: 0.7 -SHPK CARKL, SHK ENSG00000197417 Sedoheptulokinase 17 3608262-3636322 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024361, HPA064939 Approved Approved Nucleoplasm
Nuclear speckles Mixed duodenum: 13.7 -OR51D1 OR51D1Q ENSG00000197428 Olfactory receptor, family 51, subfamily D, member 1 11 4639715-4640838 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA061240 Uncertain Not detected epididymis: 0.0 -IPP KLHL27 ENSG00000197429 Intracisternal A particle-promoted polypeptide 1 45694324-45750650 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Expressed in all parathyroid gland: 19.4 -OPALIN HTMP10, TMEM10, TMP10 ENSG00000197430 Oligodendrocytic myelin paranodal and inner loop protein 10 96343216-96359365 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA014372 Supported Tissue enriched 866 cerebral cortex: 86.6 adipose tissue: 0.0 -OR13G1 ENSG00000197437 Olfactory receptor, family 13, subfamily G, member 1 1 247672118-247673041 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.4 -MAP3K5 ASK1, MAPKKK5, MEKK5 ENSG00000197442 Mitogen-activated protein kinase kinase kinase 5 6 136557047-136792518 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB007824, HPA063245, HPA064423 Approved Supported Cytosol Expressed in all adrenal gland: 116.3 -OGDHL FLJ10851 ENSG00000197444 Oxoglutarate dehydrogenase-like 10 49734643-49762379 Citric acid cycle related proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052497 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Tissue enhanced 0 kidney: 127.9;parathyroid gland: 55.3 liver: 41.6 -CYP2F1 CYP2F ENSG00000197446 Cytochrome P450, family 2, subfamily F, polypeptide 1 19 41114432-41128366 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 8 lung: 2.4;testis: 2.0 bone marrow: 0.2 -GSTK1 GST13 ENSG00000197448 Glutathione S-transferase kappa 1 7 143244093-143270854 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006311, HPA022904 Supported Supported Peroxisomes Expressed in all parathyroid gland: 369.9 -HNRNPAB ABBP1, FLJ40338, HNRPAB ENSG00000197451 Heterogeneous nuclear ribonucleoprotein A/B 5 178204507-178211180 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046688 Approved Validated Nucleoplasm Expressed in all colon: 159.3 -OR2L5 OR2L11, OR2L5P ENSG00000197454 Olfactory receptor, family 2, subfamily L, member 5 1 248021948-248022886 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -STMN3 SCLIP ENSG00000197457 Stathmin-like 3 20 63639705-63657682 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012947 Supported Tissue enhanced 0 cerebral cortex: 226.4 thyroid gland: 52.4 -PDGFA PDGF-A, PDGF1 ENSG00000197461 Platelet-derived growth factor alpha polypeptide 7 497258-520296 Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB005579 Uncertain Approved Vesicles
Microtubule organizing center Expressed in all placenta: 39.1 -GYPE GPE, MNS ENSG00000197465 Glycophorin E (MNS blood group) 4 143870867-143905563 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 bone marrow: 8.1 lung: 4.5 -COL13A1 ENSG00000197467 Collagen, type XIII, alpha 1 10 69801931-69964275 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050392 Approved Tissue enhanced 0 epididymis: 32.5 prostate: 17.8 -SPN CD43, GPL115, LSN ENSG00000197471 Sialophorin 16 29662979-29670876 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002666, HPA055244 Supported Uncertain Golgi apparatus
Plasma membrane
Cell Junctions Tissue enhanced 0 bone marrow: 38.7;lung: 33.4 lymph node: 25.8 -ZNF695 SBZF3 ENSG00000197472 Zinc finger protein 695 1 246945547-247008093 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA024743 Uncertain Approved Nuclear speckles Tissue enhanced 0 testis: 1.2 placenta: 0.6 -PCDHB11 ME2, PCDH-BETA11 ENSG00000197479 Protocadherin beta 11 5 141199582-141203779 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045042 Uncertain Approved Plasma membrane Tissue enhanced 0 parathyroid gland: 8.1 endometrium: 2.5 -ZNF628 ZEC, Zfp628 ENSG00000197483 Zinc finger protein 628 19 55476332-55484487 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044451 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 7.3 spleen: 2.8 -GALP ENSG00000197487 Galanin-like peptide 19 56176020-56185775 Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level HPA053938 Uncertain Not detected liver: 0.3 -SLC2A10 GLUT10 ENSG00000197496 Solute carrier family 2 (facilitated glucose transporter), member 10 20 46709487-46736347 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041015, HPA055673 Approved Supported Cytosol Mixed prostate: 46.7 -ZNF665 FLJ14345 ENSG00000197497 Zinc finger protein 665 19 53159213-53193386 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023437 Uncertain Approved Nuclear membrane Mixed ovary: 3.8 -RPF2 bA397G5.4, BXDC1, FLJ21087 ENSG00000197498 Ribosome production factor 2 homolog 6 110982015-111028263 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035475 Supported Supported Nucleus
Nucleoli Expressed in all testis: 28.0 -SLC28A3 CNT3 ENSG00000197506 Solute carrier family 28 (concentrative nucleoside transporter), member 3 9 84275457-84340683 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA023311, HPA024729 Approved Tissue enhanced 0 breast: 10.7;gallbladder: 11.7;skin: 9.8 bone marrow: 6.2 -FAM177B FLJ43505, RP11-452F19.2 ENSG00000197520 Family with sequence similarity 177, member B 1 222737207-222750805 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA063059 Uncertain Tissue enhanced 0 stomach: 47.6 gallbladder: 15.9 -MIB2 FLJ39787, skeletrophin, ZZANK1, ZZZ5 ENSG00000197530 Mindbomb E3 ubiquitin protein ligase 2 1 1615415-1630610 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068322 Supported Tissue enhanced 0 skeletal muscle: 12.4 cerebral cortex: 4.4 -OR6Y1 OR6Y2 ENSG00000197532 Olfactory receptor, family 6, subfamily Y, member 1 1 158547128-158548105 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -MYO5A GS1, MYH12, MYO5, MYR12 ENSG00000197535 Myosin VA 15 52307283-52529050 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001356 Approved Approved Focal adhesion sites
Microtubule organizing center Expressed in all parathyroid gland: 94.6 -C5orf56 ENSG00000197536 Chromosome 5 open reading frame 56 5 132410636-132476044 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043790 Approved Mitochondria Mixed spleen: 29.1 -GZMM LMET1, MET1 ENSG00000197540 Granzyme M (lymphocyte met-ase 1) 19 544034-549924 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015624 Supported Tissue enhanced 0 lymph node: 21.3;spleen: 20.1 appendix: 13.4 -ATG7 APG7L, DKFZp434N0735, GSA7 ENSG00000197548 Autophagy related 7 3 11272309-11557665 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007639, CAB018771 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all testis: 39.9 -SIPA1L1 E6TP1, KIAA0440 ENSG00000197555 Signal-induced proliferation-associated 1 like 1 14 71320449-71741229 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002875 Approved Approved Plasma membrane
Actin filaments Expressed in all parathyroid gland: 46.2 -TTC30A FLJ13946, IFT70A ENSG00000197557 Tetratricopeptide repeat domain 30A 2 177612992-177618966 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051714, HPA052100, HPA052487 Supported Approved Nucleus
Centrosome Mixed testis: 17.2 -SSPO FLJ36112, KIAA0543, SCO-spondin ENSG00000197558 SCO-spondin 7 149776042-149833979 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level Not detected cerebral cortex: 0.4 -ELANE ELA2, HLE, HNE, NE ENSG00000197561 Elastase, neutrophil expressed 19 851014-856247 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015409, HPA066836 Supported Tissue enriched 320 bone marrow: 1202.2 skin: 3.7 -RAB40C RARL, RASL8C ENSG00000197562 RAB40C, member RAS oncogene family 16 589357-629272 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all skin: 26.6 -PIGN MDC4, PIG-N ENSG00000197563 Phosphatidylinositol glycan anchor biosynthesis, class N 18 62043567-62187118 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039922, HPA040374 Approved Supported Plasma membrane
Cytosol Expressed in all parathyroid gland: 31.3 -COL4A6 ENSG00000197565 Collagen, type IV, alpha 6 X 108155607-108439497 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065393 Approved Endoplasmic reticulum Mixed smooth muscle: 36.4 -ZNF624 KIAA1349 ENSG00000197566 Zinc finger protein 624 17 16620737-16653856 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA023157, HPA023244 Uncertain Approved Vesicles Mixed testis: 8.9 -HHLA3 ENSG00000197568 HERV-H LTR-associating 3 1 70354805-70385339 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA031323 Approved Approved Nucleoplasm
Vesicles Mixed epididymis: 21.9 -HOXA4 HOX1, HOX1D ENSG00000197576 Homeobox A4 7 27128507-27130799 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA060088 Approved Validated Nuclear bodies Tissue enhanced 0 fallopian tube: 36.8;parathyroid gland: 34.7 esophagus: 16.4 -TOPORS LUN, RP31, TP53BPL ENSG00000197579 Topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 9 32540544-32552553 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060640, HPA065661 Supported Supported Nucleoplasm Expressed in all testis: 27.3 -BCO2 B-DIOX-II, BCDO2, FLJ34464 ENSG00000197580 Beta-carotene oxygenase 2 11 112175467-112224699 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039825, HPA040695 Uncertain Tissue enhanced 0 heart muscle: 21.5;liver: 25.6 adrenal gland: 17.0 -KCNMB2 ENSG00000197584 Potassium channel subfamily M regulatory beta subunit 2 3 178272932-178844429 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022649 Uncertain Tissue enhanced 0 epididymis: 41.5;fallopian tube: 22.1;ovary: 19.0 adrenal gland: 7.6 -ENTPD6 CD39L2, dJ738P15.3, IL6ST2, NTPDase-6 ENSG00000197586 Ectonucleoside triphosphate diphosphohydrolase 6 (putative) 20 25195693-25226729 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015491, HPA069555 Approved Supported Golgi apparatus Expressed in all cerebral cortex: 106.0 -DMBX1 OTX3, PAXB ENSG00000197587 Diencephalon/mesencephalon homeobox 1 1 46506996-46514226 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA026811 Uncertain Tissue enhanced 0 testis: 1.2 adrenal gland: 0.4 -OR11L1 ENSG00000197591 Olfactory receptor, family 11, subfamily L, member 1 1 247840928-247841896 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected thyroid gland: 0.3 -ENPP1 M6S1, NPPS, PC-1, PCA1, PDNP1 ENSG00000197594 Ectonucleotide pyrophosphatase/phosphodiesterase 1 6 131808016-131895155 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032904, HPA062066 Supported Tissue enhanced 0 parathyroid gland: 53.4;placenta: 62.4 thyroid gland: 33.9 -CCDC154 C16orf29, LOC645811 ENSG00000197599 Coiled-coil domain containing 154 16 1434383-1444556 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041158, HPA043535, HPA048237 Uncertain Approved Golgi apparatus
Plasma membrane Tissue enhanced 0 testis: 6.5 prostate: 3.7 -FAR1 FLJ22728, MLSTD2, SDR10E1 ENSG00000197601 Fatty acyl CoA reductase 1 11 13668670-13732346 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017322 Approved Validated Peroxisomes Expressed in all stomach: 59.0 -C5orf42 FLJ13231, JBTS17 ENSG00000197603 Chromosome 5 open reading frame 42 5 37106228-37249428 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036775, HPA036776 Approved Approved Cytosol Mixed thyroid gland: 13.7 -ZNF841 LOC284371 ENSG00000197608 Zinc finger protein 841 19 52064466-52095765 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed endometrium: 21.4 -MFAP5 MAGP2, MP25 ENSG00000197614 Microfibrillar associated protein 5 12 8637346-8662888 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010553 Supported Expressed in all smooth muscle: 205.4 -MYH6 ENSG00000197616 Myosin, heavy chain 6, cardiac muscle, alpha 14 23381990-23408277 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001239, HPA001349, CAB075723, CAB075724, CAB075725 Supported Tissue enriched 111 heart muscle: 2135.5 skeletal muscle: 19.1 -ZNF615 FLJ33710 ENSG00000197619 Zinc finger protein 615 19 51991332-52008230 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052422 Uncertain Approved Nucleoli
Mitochondria Mixed prostate: 28.6 -CXorf40A CXorf40, EOLA1 ENSG00000197620 Chromosome X open reading frame 40A X 149540355-149550510 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060897 Approved Expressed in all adrenal gland: 70.8 -CDC42SE1 SCIP1, SPEC1 ENSG00000197622 CDC42 small effector 1 1 151050971-151070325 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027634 Approved Supported Plasma membrane Expressed in all parathyroid gland: 117.1 -MPEG1 MPG1 ENSG00000197629 Macrophage expressed 1 11 59208510-59212951 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046801 Approved Tissue enhanced 0 spleen: 287.6 appendix: 156.3 -SERPINB2 HsT1201, PAI2, PLANH2 ENSG00000197632 Serpin peptidase inhibitor, clade B (ovalbumin), member 2 18 63871692-63903890 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015480 Supported Approved Golgi apparatus Group enriched 6 esophagus: 261.7;placenta: 69.7;skin: 106.0;tonsil: 75.5 bone marrow: 22.3 -DPP4 ADCP2, CD26, DPPIV ENSG00000197635 Dipeptidyl-peptidase 4 2 161992241-162074542 CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045970 Supported Tissue enhanced 0 parathyroid gland: 542.0 placenta: 167.8 -SERPINB13 headpin, HUR7, hurpin, PI13 ENSG00000197641 Serpin peptidase inhibitor, clade B (ovalbumin), member 13 18 63586989-63604639 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052630, HPA057129 Supported Approved Nuclear speckles
Cytosol Tissue enriched 9 esophagus: 185.3 tonsil: 21.6 -PDCD1LG2 B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2 ENSG00000197646 Programmed cell death 1 ligand 2 9 5510570-5571254 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013411 Approved Approved Cytosol Tissue enhanced 0 spleen: 21.8 lymph node: 12.2 -ZNF433 FLJ40981 ENSG00000197647 Zinc finger protein 433 19 12014732-12035741 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA073724 Uncertain Approved Nuclear bodies Expressed in all testis: 52.3 -CCER1 C12orf12, MGC26598 ENSG00000197651 Coiled-coil glutamate-rich protein 1 12 90905622-90955176 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 341 testis: 34.0 adipose tissue: 0.0 -DNAH10 FLJ43808 ENSG00000197653 Dynein, axonemal, heavy chain 10 12 123762188-123936206 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039065, HPA039066 Approved Group enriched 6 fallopian tube: 5.5;testis: 5.5 lung: 0.9 -SLC22A24 MGC34821, NET46 ENSG00000197658 Solute carrier family 22, member 24 11 63079940-63144221 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045015 Uncertain Tissue enriched 46 kidney: 4.6 adipose tissue: 0.0 -KRTAP26-1 ENSG00000197683 Keratin associated protein 26-1 21 30319124-30320316 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 18 placenta: 1.9 testis: 0.1 -SPTAN1 ENSG00000197694 Spectrin, alpha, non-erythrocytic 1 9 128552558-128633662 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004581, HPA007927 Supported Approved Vesicles
Microtubules Expressed in all cerebral cortex: 202.6 -NMB MGC17211, MGC2277, MGC3936 ENSG00000197696 Neuromedin B 15 84655129-84658563 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB019302 Approved Approved Nucleus
Vesicles
Plasma membrane Tissue enhanced 0 adipose tissue: 46.1;cerebral cortex: 47.3 thyroid gland: 14.7 -PARVA FLJ10793, FLJ12254, MXRA2 ENSG00000197702 Parvin, alpha 11 12377185-12530801 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA005964 Approved Supported Actin filaments
Focal adhesion sites
Cytosol Mixed smooth muscle: 143.9 -KLHL14 KIAA1384 ENSG00000197705 Kelch-like family member 14 18 32672671-32773062 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024777 Uncertain Supported Actin filaments
Cytosol Tissue enhanced 0 parathyroid gland: 19.4;seminal vesicle: 18.7;thyroid gland: 23.2 spleen: 11.9 -OR6C74 ENSG00000197706 Olfactory receptor, family 6, subfamily C, member 74 12 55247198-55248302 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -FAM114A1 Noxp20 ENSG00000197712 Family with sequence similarity 114, member A1 4 38867677-38945739 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067948, HPA069104, HPA069701 Uncertain Validated Nucleus
Golgi apparatus
Cytosol Expressed in all smooth muscle: 87.5 -RPE ENSG00000197713 Ribulose-5-phosphate-3-epimerase 2 210002565-210022259 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036498, HPA036499 Approved Expressed in all thyroid gland: 49.3 -ZNF460 HZF8, ZNF272 ENSG00000197714 Zinc finger protein 460 19 57280051-57293569 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053004, HPA066506 Uncertain Approved Nucleoplasm Mixed adrenal gland: 6.4 -CR1L ENSG00000197721 Complement component (3b/4b) receptor 1-like 1 207645113-207738416 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049348 Approved Not detected bone marrow: 0.8 -PHF2 CENP-35, JHDM1E, KIAA0662 ENSG00000197724 PHD finger protein 2 9 93576407-93679587 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010831 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all endometrium: 30.6 -RPS26 S26 ENSG00000197728 Ribosomal protein S26 12 56041853-56044675 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043961, HPA055803 Uncertain Validated Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all thyroid gland: 822.8 -C14orf178 FLJ25976 ENSG00000197734 Chromosome 14 open reading frame 178 14 77760830-77769742 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062581 Uncertain Mixed testis: 2.1 -SCGB1D4 IIS ENSG00000197745 Secretoglobin, family 1D, member 4 11 62296277-62299064 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 6 cervix, uterine: 75.1;epididymis: 54.3;fallopian tube: 73.5 endometrium: 11.8 -PSAP GLBA, SAP1 ENSG00000197746 Prosaposin 10 71816298-71851375 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004426, CAB004647 Supported Supported Vesicles Expressed in all cerebral cortex: 1917.1 -S100A10 42C, ANX2LG, CAL1L, CLP11, P11 ENSG00000197747 S100 calcium binding protein A10 1 151982915-151994390 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003340, CAB025484 Supported Approved Mitochondria Expressed in all esophagus: 978.3 -CFAP43 bA373N18.2, C10orf79, FLJ22944, FLJ36006, WDR96 ENSG00000197748 Cilia and flagella associated protein 43 10 104129888-104232362 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038128 Approved Nucleus Group enriched 7 fallopian tube: 77.1;testis: 102.7 lung: 12.6 -LHFPL5 DFNB67, dJ510O8.8, MGC33835, Tmhs ENSG00000197753 Lipoma HMGIC fusion partner-like 5 6 35805293-35833874 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA055110 Uncertain Tissue enhanced 0 epididymis: 12.0 bone marrow: 4.2 -RPL37A L37A ENSG00000197756 Ribosomal protein L37a 2 216498189-216579180 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065327 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all ovary: 4507.8 -HOXC6 HOX3, HOX3C ENSG00000197757 Homeobox C6 12 53990624-54030823 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA054981 Supported Nucleoplasm
Cytosol Mixed epididymis: 22.0 -TXNRD3 TGR, TR2, TRXR3 ENSG00000197763 Thioredoxin reductase 3 3 126571779-126655155 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB020802, HPA036109, HPA058257 Uncertain Validated Nucleoplasm
Cytosol Tissue enhanced 0 testis: 41.7 parathyroid gland: 18.0 -CFD ADN, DF, PFD ENSG00000197766 Complement factor D (adipsin) 19 859643-863630 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052799 Uncertain Plasma membrane Tissue enriched 7 adipose tissue: 378.7 breast: 52.3 -C9orf173 FLJ40246 ENSG00000197768 Chromosome 9 open reading frame 173 9 137251261-137253483 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044352 Uncertain Uncertain Vesicles Tissue enhanced 0 testis: 28.2 epididymis: 5.9 -MAP1LC3C ATG8J ENSG00000197769 Microtubule-associated protein 1 light chain 3 gamma 1 241995490-241999073 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA072670 Supported Cytoplasmic bodies Tissue enhanced 0 breast: 12.7;placenta: 16.0 lung: 8.1 -MCMBP C10orf119, FLJ13081, MCM-BP ENSG00000197771 Minichromosome maintenance complex binding protein 10 119829404-119892556 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013792, HPA038481 Uncertain Validated Nucleoplasm Expressed in all placenta: 63.1 -EME2 FLJ00151, SLX2B ENSG00000197774 Essential meiotic structure-specific endonuclease subunit 2 16 1773207-1781708 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045770 Uncertain Not detected stomach: 0.9 -KLHDC1 MST025 ENSG00000197776 Kelch domain containing 1 14 49693105-49753152 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA020461 Approved Supported Cytosol Mixed ovary: 9.6 -ZNF81 HFZ20, MRX45 ENSG00000197779 Zinc finger protein 81 X 47836902-48002561 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA001689 Approved Mixed parathyroid gland: 9.9 -TAF13 TAF2K, TAFII18 ENSG00000197780 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 1 109062486-109076002 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044492 Approved Validated Nucleus
Nucleoli Expressed in all smooth muscle: 50.0 -ZNF780A ZNF780 ENSG00000197782 Zinc finger protein 780A 19 40069152-40090938 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA003311 Uncertain Approved Nucleus
Centrosome Mixed parathyroid gland: 8.5 -ATAD3A FLJ10709 ENSG00000197785 ATPase family, AAA domain containing 3A 1 1512151-1534687 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058968, HPA064867, HPA065305 Approved Supported Mitochondria Expressed in all appendix: 16.6 -OR5B17 OR5B20P ENSG00000197786 Olfactory receptor, family 5, subfamily B, member 17 11 58358124-58359069 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -OR52M1 OR52M1P ENSG00000197790 Olfactory receptor, family 52, subfamily M, member 1 11 4545191-4546144 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -FAM118B FLJ21103 ENSG00000197798 Family with sequence similarity 118, member B 11 126211414-126262986 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041644, HPA042100 Approved Approved Intermediate filaments
Cytosol Expressed in all testis: 37.7 -ZNF461 GIOT-1, MGC33911 ENSG00000197808 Zinc finger protein 461 19 36637192-36666853 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA021139 Uncertain Approved Nucleus
Nucleoli
Golgi apparatus Mixed thyroid gland: 6.1 -CCDC180 BDAG1, C9orf174, DKFZp434I2420, KIAA1529 ENSG00000197816 Coiled-coil domain containing 180 9 97307304-97378524 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 5 fallopian tube: 15.6;testis: 37.7 lung: 4.8 -SLC9A8 KIAA0939, NHE8 ENSG00000197818 Solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 20 49812713-49892242 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033682 Approved Expressed in all bone marrow: 13.2 -OCLN PPP1R115 ENSG00000197822 Occludin 5 69492292-69558104 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005933, CAB013075, CAB068212, CAB068213, CAB068214 Supported Supported Plasma membrane
Cell Junctions Tissue enhanced 0 thyroid gland: 78.3 lung: 39.9 -C4orf22 ENSG00000197826 Chromosome 4 open reading frame 22 4 80335720-80963756 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043383 Approved Approved Plasma membrane
Cytosol Group enriched 23 fallopian tube: 30.3;testis: 47.2 lung: 1.7 -HIST4H4 MGC24116 ENSG00000197837 Histone cluster 4, H4 12 14767999-14771131 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB011503, CAB037279, HPA042201 Supported Supported Nucleoplasm Mixed prostate: 6.1 -CYP2A13 CPAD, CYP2A ENSG00000197838 Cytochrome P450, family 2, subfamily A, polypeptide 13 19 41088472-41096195 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046713, HPA047262 Supported Not detected testis: 0.4 -ZNF181 HHZ181, MGC44316 ENSG00000197841 Zinc finger protein 181 19 34734155-34745378 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043701, HPA062305 Uncertain Approved Nucleus Expressed in all ovary: 21.6 -OR8G1 HSTPCR25, OR8G1P, TPCR25 ENSG00000197849 Olfactory receptor, family 8, subfamily G, member 1 (gene/pseudogene) 11 124249676-124250611 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.6 -FAM212B C1orf183, FLJ31105 ENSG00000197852 Family with sequence similarity 212, member B 1 111680630-111755824 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027809, HPA027811 Approved Approved Nucleus Mixed cerebral cortex: 16.7 -ZNF44 KOX7, ZNF504, ZNF55, ZNF58 ENSG00000197857 Zinc finger protein 44 19 12224686-12294887 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA003146 Supported Approved Nucleoplasm
Microtubules
Cytosol Mixed skin: 8.6 -GPAA1 GAA1, hGAA1 ENSG00000197858 Glycosylphosphatidylinositol anchor attachment 1 8 144082590-144086216 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 68.8 -ADAMTSL2 KIAA0605 ENSG00000197859 ADAMTS-like 2 9 133532164-133575519 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045634, HPA053812 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 adrenal gland: 29.2 kidney: 11.1 -SGTB FLJ39002, Sgt2 ENSG00000197860 Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta 5 65665928-65723035 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044689, HPA063674 Approved Uncertain Nucleus Tissue enhanced 0 cerebral cortex: 52.3 appendix: 10.7 -ZNF790 FLJ20350, MGC62100 ENSG00000197863 Zinc finger protein 790 19 36817428-36850787 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056134, HPA060288 Uncertain Approved Nucleoli Mixed testis: 21.0 -PRB3 PRG ENSG00000197870 Proline-rich protein BstNI subfamily 3 12 11265924-11269805 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 3946 salivary gland: 5784.0 skin: 1.4 -FAM49A DKFZP566A1524, FLJ11080 ENSG00000197872 Family with sequence similarity 49, member A 2 16549459-16666331 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB017847, HPA060398 Approved Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 81.7 thyroid gland: 68.0 -MYO1C myr2 ENSG00000197879 Myosin IC 17 1464098-1492812 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001768, HPA005924, CAB037023 Supported Validated Nuclear bodies
Plasma membrane Expressed in all adipose tissue: 191.9 -MDS2 ENSG00000197880 Myelodysplastic syndrome 2 translocation associated 1 23581495-23640568 Disease related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052999 Uncertain Tissue enhanced 0 lymph node: 7.8;tonsil: 4.1 spleen: 2.9 -NKIRAS1 kappaB-Ras1, KBRAS1 ENSG00000197885 NFKB inhibitor interacting Ras-like 1 3 23891660-23946591 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062521 Approved Microtubules Expressed in all cerebral cortex: 50.5 -OR1S2 ENSG00000197887 Olfactory receptor, family 1, subfamily S, member 2 11 58203202-58204181 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA049304 Uncertain Not detected epididymis: 0.0 -UGT2B17 ENSG00000197888 UDP glucuronosyltransferase 2 family, polypeptide B17 4 68537184-68568527 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045108 Supported Tissue enhanced 0 colon: 378.9;duodenum: 381.0;small intestine: 532.1 rectum: 153.4 -MEIG1 bA2K17.3, SPATA39 ENSG00000197889 Meiosis/spermiogenesis associated 1 10 14959439-14988050 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA044594 Uncertain Group enriched 12 fallopian tube: 6.6;testis: 12.9 cerebral cortex: 0.8 -SLC22A12 OAT4L, RST, URAT1 ENSG00000197891 Solute carrier family 22 (organic anion/urate transporter), member 12 11 64590641-64602353 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024575 Supported Tissue enriched 195 kidney: 104.6 adipose tissue: 0.5 -KIF13B GAKIN, KIAA0639 ENSG00000197892 Kinesin family member 13B 8 29067279-29263124 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025023 Approved Tissue enriched 10 parathyroid gland: 205.1 kidney: 20.1 -NRAP ENSG00000197893 Nebulin-related anchoring protein 10 113588716-113664127 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037953, HPA037954 Approved Group enriched 19 heart muscle: 198.7;skeletal muscle: 814.2 esophagus: 26.5 -ADH5 ADH-3, ADHX, FDH ENSG00000197894 Alcohol dehydrogenase 5 (class III), chi polypeptide 4 99070978-99088801 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044578, HPA061919 Approved Expressed in all endometrium: 197.0 -SLC22A6 OAT1, PAHT, ROAT1 ENSG00000197901 Solute carrier family 22 (organic anion transporter), member 6 11 62936385-62984983 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 63 kidney: 199.6 cerebral cortex: 3.1 -HIST1H2BK H2BFAiii, H2BFT ENSG00000197903 Histone cluster 1, H2bk 6 27146418-27146798 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Expressed in all prostate: 96.7 -TEAD4 EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1 ENSG00000197905 TEA domain family member 4 12 2959330-3040673 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056896 Uncertain Supported Nucleoplasm Tissue enhanced 0 skeletal muscle: 38.8 thyroid gland: 18.0 -SPG7 CAR, CMAR, SPG5C ENSG00000197912 Spastic paraplegia 7 (pure and complicated autosomal recessive) 16 89490917-89557768 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 52.3 -HRNR FLG3, S100A16, S100a18 ENSG00000197915 Hornerin 1 152212082-152224193 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031469 Uncertain Approved Mitochondria Not detected skin: 0.7 -IFNA1 IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@ ENSG00000197919 Interferon, alpha 1 9 21409169-21441316 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047557 Uncertain Not detected epididymis: 0.2 -HES5 bHLHb38 ENSG00000197921 Hes family bHLH transcription factor 5 1 2528745-2530245 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA065458 Approved Nucleoplasm
Nuclear speckles
Cytosol Tissue enhanced 0 cerebral cortex: 1.8 skin: 0.9 -ZNF677 MGC48625 ENSG00000197928 Zinc finger protein 677 19 53235381-53254898 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA023106, HPA024796 Approved Approved Nucleus
Centrosome Expressed in all testis: 71.0 -ERO1A ERO1-alpha, Ero1alpha, ERO1L ENSG00000197930 Endoplasmic reticulum oxidoreductase alpha 14 52639916-52695900 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026653, HPA030053, CAB034294 Supported Expressed in all esophagus: 182.3 -ZNF823 HSZFP36 ENSG00000197933 Zinc finger protein 823 19 11721265-11739009 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed parathyroid gland: 12.3 -ZNF311 ENSG00000197935 Zinc finger protein 311 6 28994785-29005316 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA050541 Uncertain Not detected fallopian tube: 0.4 -ZNF347 ZNF1111 ENSG00000197937 Zinc finger protein 347 19 53124072-53159075 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA023448 Uncertain Approved Microtubules Expressed in all spleen: 14.4 -OR5H2 ENSG00000197938 Olfactory receptor, family 5, subfamily H, member 2 3 98282888-98283832 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -PLCG2 ENSG00000197943 Phospholipase C, gamma 2 (phosphatidylinositol-specific) 16 81739097-81962693 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004280, HPA020099, HPA020100 Supported Approved Vesicles Tissue enhanced 0 lymph node: 79.9 tonsil: 68.3 -FCHSD1 FLJ00007 ENSG00000197948 FCH and double SH3 domains 1 5 141639302-141651419 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043795 Approved Approved Nucleoplasm
Cytosol Mixed parathyroid gland: 41.4 -ZNF71 Cos26, EZFIT ENSG00000197951 Zinc finger protein 71 19 56595264-56626481 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018124 Uncertain Approved Nucleus
Nucleoli Mixed cerebral cortex: 5.4 -AADACL2 MGC72001 ENSG00000197953 Arylacetamide deacetylase-like 2 3 151733916-151761339 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 14 skin: 31.2 breast: 2.2 -S100A6 2A9, CABP, CACY, PRA ENSG00000197956 S100 calcium binding protein A6 1 153534599-153536244 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002601, HPA007575, CAB040549 Supported Validated Cytosol Expressed in all lung: 1681.2 -RPL12 L12 ENSG00000197958 Ribosomal protein L12 9 127447674-127451405 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003403 Approved Expressed in all ovary: 3666.1 -DNM3 KIAA0820 ENSG00000197959 Dynamin 3 1 171841498-172418466 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064121 Approved Golgi apparatus Tissue enhanced 0 cerebral cortex: 41.2 adrenal gland: 15.7 -ZNF121 D19S204, ZHC32, ZNF20 ENSG00000197961 Zinc finger protein 121 19 9560353-9584533 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA054961 Uncertain Uncertain Nucleoplasm
Nucleoli
Centrosome Expressed in all parathyroid gland: 23.1 -MPZL1 FLJ21047, PZR ENSG00000197965 Myelin protein zero-like 1 1 167721192-167791919 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026966, HPA063538 Approved Supported Vesicles
Plasma membrane Expressed in all breast: 111.3 -VPS13A CHAC, KIAA0986 ENSG00000197969 Vacuolar protein sorting 13 homolog A (S. cerevisiae) 9 77177353-77421541 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021652, HPA021662 Supported Expressed in all skin: 40.3 -MBP ENSG00000197971 Myelin basic protein 18 76978827-77133683 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002300, HPA049222, HPA064368 Supported Supported Approved Plasma membrane Tissue enriched 30 cerebral cortex: 2938.8 parathyroid gland: 97.8 -AKAP17A 721P, CCDC133, CXYorf3, DXYS155E, MGC39904, SFRS17A, XE7, XE7Y ENSG00000197976 A kinase (PRKA) anchor protein 17A X 1591593-1602514 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043247, HPA051020 Supported Supported Nuclear speckles
Cytosol Expressed in all spleen: 61.7 -ELOVL2 Ssc2 ENSG00000197977 ELOVL fatty acid elongase 2 6 10980759-11044314 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 liver: 27.6;parathyroid gland: 39.5;placenta: 49.8 cerebral cortex: 22.9 -GOLGA6L9 GOLGA6L20 ENSG00000197978 Golgin A6 family-like 9 15 82430018-82439153 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected stomach: 0.9 -LEKR1 FLJ16641 ENSG00000197980 Leucine, glutamate and lysine rich 1 3 156825481-157046129 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044039 Uncertain Tissue enhanced 0 testis: 27.1 fallopian tube: 6.6 -C1orf122 FLJ45459 ENSG00000197982 Chromosome 1 open reading frame 122 1 37806979-37809454 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Expressed in all cerebral cortex: 52.9 -RP11-310K10.1 ENSG00000197991 Protocadherin-20 13 61409858-61427849 Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.5 -CLEC9A CD370, DNGR-1, HEEE9341, UNQ9341 ENSG00000197992 C-type lectin domain family 9, member A 12 10030677-10066027 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 8.0;spleen: 6.7 testis: 5.4 -KEL CD238, ECE3 ENSG00000197993 Kell blood group, metallo-endopeptidase 7 142941114-142962681 Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 14.6;testis: 19.4 lymph node: 6.5 -NOL8 C9orf34, FLJ20736, Nop132 ENSG00000198000 Nucleolar protein 8 9 92297358-92325636 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044440, HPA062922 Uncertain Supported Nucleoli Expressed in all parathyroid gland: 24.0 -IRAK4 NY-REN-64 ENSG00000198001 Interleukin-1 receptor-associated kinase 4 12 43758944-43789543 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016685, CAB022077 Uncertain Approved Nucleoli
Microtubules
Cytosol Mixed lymph node: 20.6 -CCDC151 MGC20983 ENSG00000198003 Coiled-coil domain containing 151 19 11420604-11435782 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044184, HPA054626 Supported Approved Nucleoplasm Tissue enhanced 0 fallopian tube: 13.6;parathyroid gland: 7.0;testis: 7.5 cerebral cortex: 2.1 -DLGAP2 DAP-2 ENSG00000198010 Discs, large (Drosophila) homolog-associated protein 2 8 1501366-1708476 Nuclear receptors, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030320 Uncertain Group enriched 10 cerebral cortex: 1.9;testis: 5.5 kidney: 0.3 -MRPL42 HSPC204, MRP-L31, MRPL31, MRPS32, PTD007, RPML31 ENSG00000198015 Mitochondrial ribosomal protein L42 12 93467488-93516213 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039398 Approved Supported Plasma membrane
Mitochondria Expressed in all parathyroid gland: 56.2 -ENTPD7 FLJ30978, LALP1 ENSG00000198018 Ectonucleoside triphosphate diphosphohydrolase 7 10 99659506-99706240 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA014351 Uncertain Approved Nucleoplasm Mixed small intestine: 24.2 -FCGR1B CD64b ENSG00000198019 Fc fragment of IgG, high affinity Ib, receptor (CD64) 1 121087345-121096310 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 appendix: 28.1;epididymis: 61.7 placenta: 17.2 -SPANXA1 CT11.1, NAP-X, SPAN-Xa, SPAN-Xb, SPANX ENSG00000198021 Sperm protein associated with the nucleus, X-linked, family member A1 X 141583674-141698444 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046423 Uncertain Supported Nucleoplasm
Vesicles Tissue enriched 340 testis: 34.0 adipose tissue: 0.0 -ZNF335 bA465L10.2, NIF-1 ENSG00000198026 Zinc finger protein 335 20 45948653-45972172 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063999, HPA071230 Validated Nucleoplasm Expressed in all skin: 24.7 -ZNF560 FLJ31986 ENSG00000198028 Zinc finger protein 560 19 9466507-9498607 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 9 testis: 11.9 placenta: 1.2 -TUBA3C bA408E5.3, TUBA2 ENSG00000198033 Tubulin, alpha 3c 13 19173770-19181852 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039247, HPA043684, HPA063394 Uncertain Supported Microtubules Tissue enriched 2145 testis: 513.4 epididymis: 0.2 -RPS4X CCG2, DXS306, FLJ40595, RPS4, S4, SCAR, SCR10 ENSG00000198034 Ribosomal protein S4, X-linked X 72255679-72277300 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000857 Supported Expressed in all ovary: 1941.1 -ZNF273 HZF9 ENSG00000198039 Zinc finger protein 273 7 64870172-64930966 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Mixed testis: 2.8 -ZNF84 HPF2 ENSG00000198040 Zinc finger protein 84 12 133037292-133063304 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA028860 Approved Supported Nucleoplasm Expressed in all thyroid gland: 32.9 -MAK16 MAK16L, RBM13 ENSG00000198042 MAK16 homolog 8 33484750-33501260 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044417, HPA050574 Uncertain Supported Nucleoli
Vesicles Expressed in all thyroid gland: 12.6 -ZNF667 FLJ14011 ENSG00000198046 Zinc finger protein 667 19 56439325-56478065 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA030731, HPA046673 Uncertain Approved Nucleus Mixed cerebral cortex: 18.3 -AVPR1B AVPR3 ENSG00000198049 Arginine vasopressin receptor 1B 1 206109692-206117699 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level No evidence Evidence at transcript level Not detected stomach: 0.3 -SIRPA BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2 ENSG00000198053 Signal-regulatory protein alpha 20 1894167-1940592 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002776, CAB015122, HPA054437, HPA058511 Approved Expressed in all cerebral cortex: 208.5 -DSCR8 C21orf65, CT25.1a, CT25.1b, MMA-1a, MMA-1b, MTAG2 ENSG00000198054 Down syndrome critical region 8 21 38121451-38188016 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 7 testis: 33.5 placenta: 4.8 -GRK6 GPRK6 ENSG00000198055 G protein-coupled receptor kinase 6 5 177403204-177442901 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015327, HPA018903 Approved Approved Mitochondria Expressed in all bone marrow: 87.7 -PRIM1 ENSG00000198056 Primase, DNA, polypeptide 1 (49kDa) 12 56731596-56752373 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040010 Uncertain Supported Vesicles Expressed in all testis: 21.7 -MARCH5 FLJ20445, MARCH-V, RNF153 ENSG00000198060 Membrane-associated ring finger (C3HC4) 5 10 92291163-92353964 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056596 Supported Mitochondria Expressed in all thyroid gland: 28.6 -POTEH A26C3, ACTBL1, CT104.7, POTE22 ENSG00000198062 POTE ankyrin domain family, member H 22 15690026-15721631 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042822 Uncertain Group enriched 36 prostate: 5.7;testis: 1.3 adipose tissue: 0.0 -RP11-347C12.1 ENSG00000198064 Putative NPIP-like protein LOC613037 16 30222937-30254510 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA053611 Approved Approved Nucleoplasm Mixed skin: 9.1 -AKR1B10 AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI ENSG00000198074 Aldo-keto reductase family 1, member B10 (aldose reductase) 7 134527592-134541408 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020280, CAB070163, HPA073633 Supported Supported Plasma membrane
Cytosol Tissue enhanced 0 duodenum: 653.4;gallbladder: 284.3;small intestine: 396.0;stomach: 417.4 esophagus: 90.2 -SULT1C4 SULT1C, SULT1C2 ENSG00000198075 Sulfotransferase family, cytosolic, 1C, member 4 2 108377911-108388057 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034530 Approved Cytosol Tissue enhanced 0 gallbladder: 41.6 ovary: 31.1 -CYP2A7 CYP2A ENSG00000198077 Cytochrome P450, family 2, subfamily A, polypeptide 7 19 40875439-40882752 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB033510, HPA046713, HPA047262 Supported Tissue enriched 113 liver: 60.8 breast: 0.5 -ZBTB14 ZFP161, ZNF478 ENSG00000198081 Zinc finger and BTB domain containing 14 18 5289019-5297053 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050758, HPA070819 Uncertain Validated Nucleus
Nucleoli
Cytosol Expressed in all lymph node: 29.3 -KRTAP9-9 KAP9.5, KAP9.9, KRTAP9-5 ENSG00000198083 Keratin associated protein 9-9 17 41226653-41256364 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -CD2AP CMS ENSG00000198087 CD2-associated protein 6 47477789-47627263 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003267, HPA003326, CAB004352 Supported Validated Plasma membrane
Cytosol Expressed in all small intestine: 66.9 -NUP62CL FLJ20130 ENSG00000198088 Nucleoporin 62kDa C-terminal like X 107123427-107206433 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA001884 Approved Tissue enhanced 0 fallopian tube: 27.2 testis: 22.0 -SFI1 KIAA0542, PISD, PPP1R139 ENSG00000198089 SFI1 centrin binding protein 22 31488688-31618586 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed lymph node: 14.0 -KRTAP4-6 KAP4.15, KAP4.6, KRTAP4-15 ENSG00000198090 Keratin associated protein 4-6 17 41139433-41140487 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -TMPRSS11F FLJ16046 ENSG00000198092 Transmembrane protease, serine 11F 4 68053198-68129880 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA026911 Uncertain Group enriched 7 esophagus: 16.8;skin: 11.0;tonsil: 3.8 breast: 1.5 -ZNF649 FLJ12644 ENSG00000198093 Zinc finger protein 649 19 51889224-51905040 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026541 Uncertain Expressed in all prostate: 34.0 -ADH4 ADH-2 ENSG00000198099 Alcohol dehydrogenase 4 (class II), pi polypeptide 4 99123657-99157792 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020525 Supported Uncertain Nucleus
Cytosol Tissue enriched 15 liver: 2627.7 duodenum: 170.9 -OR2T6 OR2T6P, OR2T9, OST703 ENSG00000198104 Olfactory receptor, family 2, subfamily T, member 6 1 248387609-248388535 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -ZNF248 bA162G10.3 ENSG00000198105 Zinc finger protein 248 10 37776526-37858106 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA018237, HPA018287, HPA018455 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 25.3 -CHSY3 CHSY-2, CSS3 ENSG00000198108 Chondroitin sulfate synthase 3 5 129904472-130186634 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044612 Uncertain Tissue enhanced 0 cervix, uterine: 7.1 gallbladder: 4.5 -TOR4A C9orf167, FLJ20245 ENSG00000198113 Torsin family 4, member A 9 137277749-137282641 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044913 Approved Approved Nucleoplasm Mixed stomach: 11.7 -LPAR1 edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1 ENSG00000198121 Lysophosphatidic acid receptor 1 9 110873263-111038458 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050667 Approved Nuclear speckles
Plasma membrane Mixed cervix: 90.9 -MB PVALB ENSG00000198125 Myoglobin 22 35606764-35637951 Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000060, HPA003123 Supported Group enriched 12 heart muscle: 6691.4;skeletal muscle: 12286.7 esophagus: 767.2 -OR2L3 ENSG00000198128 Olfactory receptor, family 2, subfamily L, member 3 1 248060682-248061620 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected thyroid gland: 0.3 -DEFB107B HsT21816 ENSG00000198129 Defensin, beta 107B 8 7495846-7509311 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045626 Approved Tissue enriched 2765 epididymis: 478.6 endometrium: 0.1 -HIBCH ENSG00000198130 3-hydroxyisobutyryl-CoA hydrolase 2 190189735-190344193 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036540, HPA036541 Supported Approved Nucleoplasm
Mitochondria Expressed in all kidney: 183.7 -ZNF544 AF020591 ENSG00000198131 Zinc finger protein 544 19 58228594-58277495 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA002732 Approved Approved Nucleoplasm Expressed in all testis: 49.3 -TMEM229B C14orf83, FLJ33387 ENSG00000198133 Transmembrane protein 229B 14 67447084-67533739 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046562 Approved Mixed duodenum: 16.2 -SOWAHC ANKRD57, C2orf26, FLJ21870 ENSG00000198142 Sosondowah ankyrin repeat domain family member C 2 109614334-109618990 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056131 Supported Approved Cytosol Mixed esophagus: 36.5 -ZNF770 FLJ20582, PRO1914 ENSG00000198146 Zinc finger protein 770 15 34978341-34988287 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA024518 Approved Expressed in all thyroid gland: 73.3 -NPIPB6 ENSG00000198156 Nuclear pore complex interacting protein family, member B6 16 28342555-28363508 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA011188, HPA053611 Approved Approved Nucleoplasm Tissue enriched 23 testis: 54.7 skin: 2.3 -HMGN5 NSBP1 ENSG00000198157 High mobility group nucleosome binding domain 5 X 81113701-81201942 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000511 Approved Supported Nucleus Expressed in all testis: 201.8 -MIER1 hMI-ER1, KIAA1610, MI-ER1 ENSG00000198160 Mesoderm induction early response 1, transcriptional regulator 1 66924895-66988619 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019589, HPA050306 Supported Validated Nucleoplasm Expressed in all bone marrow: 63.2 -MAN1A2 MAN1B ENSG00000198162 Mannosidase, alpha, class 1A, member 2 1 117367449-117528872 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034559, HPA057364 Supported Validated Golgi apparatus Expressed in all parathyroid gland: 43.5 -SVIP DKFZp313A2432 ENSG00000198168 Small VCP/p97-interacting protein 11 22813799-22830299 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039807 Uncertain Expressed in all thyroid gland: 39.0 -ZNF251 ENSG00000198169 Zinc finger protein 251 8 144720907-144756417 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA018290 Approved Approved Nucleoplasm Mixed thyroid gland: 13.7 -DDRGK1 C20orf116, dJ1187M17.3 ENSG00000198171 DDRGK domain containing 1 20 3190350-3204685 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013373, HPA013705 Approved Supported Nucleoli
Endoplasmic reticulum Expressed in all adrenal gland: 72.7 -FAM47C ENSG00000198173 Family with sequence similarity 47, member C X 37008397-37011666 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 28 testis: 4.8 parathyroid gland: 0.1 -TFDP1 Dp-1, DP1, DRTF1 ENSG00000198176 Transcription factor Dp-1 13 113584721-113641470 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033605, HPA044754, HPA068909 Supported Validated Nucleoplasm Expressed in all bone marrow: 100.1 -CLEC4C BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL ENSG00000198178 C-type lectin domain family 4, member C 12 7729415-7751605 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA029432 Approved Tissue enhanced 0 lymph node: 6.1;spleen: 4.7;tonsil: 4.7 breast: 1.8 -ZNF607 FLJ14802, MGC13071 ENSG00000198182 Zinc finger protein 607 19 37696363-37719790 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA049465, HPA055018 Uncertain Approved Nucleoplasm Mixed parathyroid gland: 9.4 -BPIFA1 bA49G10.5, LUNX, PLUNC, SPLUNC1 ENSG00000198183 BPI fold containing family A, member 1 20 33235995-33243311 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025669 Supported Group enriched 8 cervix, uterine: 9.7;lung: 26.6 urinary bladder: 2.3 -ZNF334 bA179N14.1 ENSG00000198185 Zinc finger protein 334 20 46499630-46513559 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA050022 Uncertain Approved Nucleus
Cytosol Mixed ovary: 19.3 -HSD17B11 17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2 ENSG00000198189 Hydroxysteroid (17-beta) dehydrogenase 11 4 87336610-87391386 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021608 Approved Supported Lipid droplets Expressed in all small intestine: 301.2 -SZT2 C1orf84, FLJ10387, FLJ34502, KIAA0467, RP11-506B15.1, SZT2A, SZT2B ENSG00000198198 Seizure threshold 2 homolog (mouse) 1 43389882-43452650 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029012 Approved Approved Nucleoplasm
Vesicles
Actin filaments Expressed in all parathyroid gland: 21.0 -SULT1C2 ST1C1, SULT1C1 ENSG00000198203 Sulfotransferase family, cytosolic, 1C, member 2 2 108288639-108309915 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007190 Approved Tissue enhanced 0 kidney: 68.6;stomach: 151.1 duodenum: 29.3 -ZXDA ZNF896 ENSG00000198205 Zinc finger, X-linked, duplicated A X 57906708-57910820 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA043789 Approved Approved Nucleoplasm Mixed ovary: 5.3 -RPS6KL1 MGC11287 ENSG00000198208 Ribosomal protein S6 kinase-like 1 14 74903954-74923396 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA027451, HPA027794 Approved Approved Nucleoplasm Tissue enhanced 0 cerebral cortex: 31.4 testis: 14.6 -RP11-566K11.2 ENSG00000198211 16 89919165-89936092 Predicted membrane proteins Evidence at protein level Evidence at protein level CAB011512, HPA043640, HPA046280 Uncertain Validated Microtubules Tissue enhanced 0 skin: 1.1 testis: 0.7 -CACNA1E BII, CACH6, CACNL1A6, Cav2.3 ENSG00000198216 Calcium channel, voltage-dependent, R type, alpha 1E subunit 1 181413102-181808084 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042515 Approved Plasma membrane
Actin filaments
Cytosol Tissue enriched 7 cerebral cortex: 10.3 adrenal gland: 1.3 -QRICH1 FLJ20259 ENSG00000198218 Glutamine-rich 1 3 49029707-49094363 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037677, HPA037678 Approved Validated Nucleoplasm Expressed in all testis: 78.8 -CSF2RA CD116, CSF2R ENSG00000198223 Colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) X 1268800-1310381 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB016148 Uncertain Tissue enhanced 0 placenta: 93.5 appendix: 36.4 -FKBP1C bA184C23.2 ENSG00000198225 FK506 binding protein 1C 6 63211446-63213024 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA051798, HPA057830 Uncertain Approved Microtubules Not detected appendix: 0.4 -DDX42 RHELP, RNAHP, SF3b125, SF3B8 ENSG00000198231 DEAD (Asp-Glu-Ala-Asp) box helicase 42 17 63773603-63819317 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023447, HPA023571, HPA025941 Supported Validated Nuclear speckles Expressed in all testis: 74.1 -RPL23A L23A ENSG00000198242 Ribosomal protein L23a 17 28719393-28724359 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051754, HPA077474 Approved Approved Nucleoli fibrillar center
Cytosol Expressed in all ovary: 2748.3 -SLC29A3 ENT3, FLJ11160 ENSG00000198246 Solute carrier family 29 (equilibrative nucleoside transporter), member 3 10 71319258-71363385 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046085, HPA054976, HPA057905 Approved Supported Golgi apparatus
Vesicles Mixed placenta: 18.7 -STYX ENSG00000198252 Serine/threonine/tyrosine interacting protein 14 52730180-52774998 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040290 Uncertain Approved Nucleoplasm Expressed in all testis: 20.5 -UBL5 ENSG00000198258 Ubiquitin-like 5 19 9827892-9830115 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all epididymis: 572.1 -HELZ DHRC, HUMORF5, KIAA0054 ENSG00000198265 Helicase with zinc finger 17 67070438-67245989 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028276 Approved Approved Nucleoli
Plasma membrane
Actin filaments Expressed in all parathyroid gland: 32.3 -TMEM116 FLJ90167 ENSG00000198270 Transmembrane protein 116 12 111931282-112013185 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040720 Approved Approved Nucleoplasm
Microtubules Tissue enhanced 0 parathyroid gland: 56.1 testis: 47.8 -KRTAP4-5 KAP4.5 ENSG00000198271 Keratin associated protein 4-5 17 41148924-41149802 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -UCKL1 FLJ20517, URKL1 ENSG00000198276 Uridine-cytidine kinase 1-like 1 20 63939829-63956415 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004722, HPA004769 Approved Approved Endoplasmic reticulum Expressed in all spleen: 40.9 -OR5B21 ENSG00000198283 Olfactory receptor, family 5, subfamily B, member 21 11 58507175-58508105 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.3 -CARD11 BIMP3, CARMA1 ENSG00000198286 Caspase recruitment domain family, member 11 7 2906141-3043945 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052984 Approved Tissue enhanced 0 lymph node: 55.1;spleen: 41.0 appendix: 29.3 -ZNF485 ENSG00000198298 Zinc finger protein 485 10 43606407-43617903 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059356 Uncertain Mixed testis: 7.1 -PEG3 KIAA0287, ZKSCAN22, ZNF904, ZSCAN24 ENSG00000198300 Paternally expressed 3 19 56810083-56840728 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026070 Approved Supported Nucleoplasm Tissue enhanced 0 ovary: 339.5;placenta: 196.4 adrenal gland: 102.6 -SDAD1 FLJ10498 ENSG00000198301 SDA1 domain containing 1 4 75940950-75990962 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035949 Uncertain Supported Nucleus
Nucleoli Expressed in all testis: 37.9 -ZKSCAN8 LD5-1, ZNF192, ZSCAN40 ENSG00000198315 Zinc finger with KRAB and SCAN domains 8 6 28141910-28159472 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003483 Approved Approved Nucleus
Cytosol Expressed in all endometrium: 24.8 -FAM109A FLJ32356 ENSG00000198324 Family with sequence similarity 109, member A 12 111360651-111369121 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all small intestine: 31.4 -TMEM239 ENSG00000198326 Transmembrane protein 239 20 2816302-2820284 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 248 testis: 39.1 placenta: 0.1 -HYLS1 FLJ32915 ENSG00000198331 Hydrolethalus syndrome 1 11 125883614-125900648 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041210 Uncertain Supported Plasma membrane
Cytosol Tissue enriched 6 testis: 37.4 smooth muscle: 6.6 -MYL4 ALC1, AMLC, GT1, PRO1957 ENSG00000198336 Myosin, light chain 4, alkali; atrial, embryonic 17 47200446-47223679 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046859, HPA051884, HPA063034 Supported Approved Plasma membrane Tissue enriched 28 heart muscle: 2225.0 bone marrow: 80.1 -ZNF442 FLJ14356 ENSG00000198342 Zinc finger protein 442 19 12345949-12365905 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045738, HPA053407 Uncertain Approved Nuclear membrane
Vesicles Mixed ovary: 6.0 -ZNF813 FLJ16542 ENSG00000198346 Zinc finger protein 813 19 53467735-53496255 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA056406 Uncertain Approved Vesicles Mixed prostate: 8.8 -HOXC4 HOX3, HOX3E ENSG00000198353 Homeobox C4 12 54016931-54056030 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053910 Supported Nucleus Tissue enhanced 0 fallopian tube: 33.6 kidney: 9.4 -DCAF12L2 WDR40C ENSG00000198354 DDB1 and CUL4 associated factor 12-like 2 X 126164531-126165951 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044737, HPA048981, HPA053138 Approved Approved Cytosol Tissue enhanced 0 epididymis: 17.8;testis: 9.2 seminal vesicle: 6.5 -PIM3 ENSG00000198355 Pim-3 proto-oncogene, serine/threonine kinase 22 49960513-49964080 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA068758 Supported Cytosol Expressed in all bone marrow: 61.3 -ASNA1 ARSA-I, GET3, TRC40 ENSG00000198356 ArsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 19 12737139-12748323 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045951, HPA048087 Approved Validated Nucleus
Nucleoli Expressed in all thyroid gland: 93.7 -ASPH BAH, CASQ2BP1, HAAH, JCTN ENSG00000198363 Aspartate beta-hydroxylase 8 61500556-61714640 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055161, HPA059303 Uncertain Supported Endoplasmic reticulum Expressed in all adipose tissue: 394.0 -SPRED2 FLJ21897, FLJ31917, Spred-2 ENSG00000198369 Sprouty-related, EVH1 domain containing 2 2 65310851-65432637 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038256 Uncertain Nucleoplasm
Cytosol Expressed in all cerebral cortex: 44.1 -WWP2 AIP2 ENSG00000198373 WW domain containing E3 ubiquitin protein ligase 2 16 69762306-69941741 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all parathyroid gland: 48.8 -GFPT1 GFA, GFAT, GFAT1, GFPT ENSG00000198380 Glutamine--fructose-6-phosphate transaminase 1 2 69319769-69387254 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047240 Approved Nucleus
Nucleoli Expressed in all thyroid gland: 81.6 -UVRAG VPS38 ENSG00000198382 UV radiation resistance associated 11 75815167-76143195 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016932 Uncertain Expressed in all parathyroid gland: 42.0 -KRTAP13-1 KAP13.1 ENSG00000198390 Keratin associated protein 13-1 21 30396074-30396822 Predicted intracellular proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected testis: 0.3 -ZNF26 FLJ20755, KOX20 ENSG00000198393 Zinc finger protein 26 12 132986365-133032952 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA018329, HPA042406 Uncertain Approved Nuclear bodies
Mitochondria Mixed epididymis: 7.1 -TMEM207 ENSG00000198398 Transmembrane protein 207 3 190428655-190449876 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014332 Uncertain Tissue enriched 62 kidney: 18.5 testis: 0.2 -ITSN2 KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP ENSG00000198399 Intersectin 2 2 24202864-24360714 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA036475 Approved Approved Vesicles
Plasma membrane Expressed in all thyroid gland: 84.6 -NTRK1 MTC, TRK, TRKA ENSG00000198400 Neurotrophic tyrosine kinase, receptor, type 1 1 156815640-156881850 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004606, HPA035799, HPA076570 Approved Uncertain Vesicles
Cytosol Tissue enriched 6 adrenal gland: 9.6 testis: 1.6 -MGEA5 MEA5, NCOAT, OGA ENSG00000198408 Meningioma expressed antigen 5 (hyaluronidase) 10 101784443-101818465 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036141, HPA076501 Approved Supported Cytosol Expressed in all parathyroid gland: 127.3 -MT1F MT1 ENSG00000198417 Metallothionein 1F 16 56657694-56660698 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 kidney: 283.9;thyroid gland: 816.1 small intestine: 141.3 -TCAF1 FAM115A, KIAA0738 ENSG00000198420 TRPM8 channel-associated factor 1 7 143851375-143902198 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011732, HPA061989 Approved Supported Nucleoplasm
Mitochondria Expressed in all placenta: 115.3 -ZNF69 Cos5 ENSG00000198429 Zinc finger protein 69 19 11887784-11914329 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA047845 Uncertain Uncertain Nucleus Tissue enhanced 0 parathyroid gland: 25.3 kidney: 10.3 -TXNRD1 GRIM-12, Trxr1, TXNR ENSG00000198431 Thioredoxin reductase 1 12 104215779-104350305 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001395, CAB004607, CAB015834, HPA043871 Approved Supported Nucleus Expressed in all adrenal gland: 109.8 -NRARP MGC61598 ENSG00000198435 NOTCH-regulated ankyrin repeat protein 9 137300482-137302251 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA025729 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 colon: 39.2 rectum: 22.4 -ZNF583 FLJ31030 ENSG00000198440 Zinc finger protein 583 19 56397966-56436035 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA023805, HPA023957 Uncertain Approved Nucleoli
Cytosol Mixed testis: 13.7 -KRTAP4-1 KAP4.1, KAP4.10, KRTAP4-10 ENSG00000198443 Keratin associated protein 4-1 17 41184102-41185342 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected small intestine: 0.3 -CCT8L2 CESK1 ENSG00000198445 Chaperonin containing TCP1, subunit 8 (theta)-like 2 22 16590751-16592810 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 171 testis: 17.1 adipose tissue: 0.0 -ZNF568 DKFZp686B0797 ENSG00000198453 Zinc finger protein 568 19 36916329-36998700 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052061 Uncertain Mixed parathyroid gland: 14.1 -ZXDB ZNF905 ENSG00000198455 Zinc finger, X-linked, duplicated B X 57591652-57597545 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043789 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 9.9 -ZNF480 MGC32104 ENSG00000198464 Zinc finger protein 480 19 52297177-52325922 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA042218 Uncertain Supported Nucleoplasm Mixed lymph node: 15.4 -ZNF587 FLJ14710, FLJ20813, UBF-fl, ZF6 ENSG00000198466 Zinc finger protein 587 19 57849857-57865112 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA042125, HPA043288, HPA056213 Uncertain Uncertain Nucleoplasm Mixed rectum: 15.6 -TPM2 AMCD1, DA1, NEM4 ENSG00000198467 Tropomyosin 2 (beta) 9 35681992-35691020 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047089, HPA053624 Approved Tissue enriched 6 skeletal muscle: 13469.0 smooth muscle: 2265.6 -RTP2 MGC78665, Z3CXXC2 ENSG00000198471 Receptor (chemosensory) transporter protein 2 3 187698259-187702557 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA026875 Uncertain Tissue enhanced 0 testis: 1.0 skeletal muscle: 0.5 -SH3BGRL2 ENSG00000198478 SH3 domain binding glutamate-rich protein like 2 6 79631283-79703659 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047486 Approved Supported Nucleoplasm Expressed in all thyroid gland: 97.9 -ZNF808 ENSG00000198482 Zinc finger protein 808 19 52527652-52564464 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed thyroid gland: 15.1 -ANKRD35 FLJ25124 ENSG00000198483 Ankyrin repeat domain 35 1 145866560-145885866 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA035452, HPA035453 Approved Approved Plasma membrane Group enriched 6 cervix, uterine: 30.6;esophagus: 16.7;skin: 69.9 tonsil: 6.3 -B3GNT6 B3Gn-T6 ENSG00000198488 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 11 77034398-77041973 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012158, HPA039805 Supported Approved Tissue enhanced 0 colon: 22.1;rectum: 18.6;stomach: 24.0 small intestine: 8.0 -YTHDF2 CAHL, HGRG8, NY-REN-2 ENSG00000198492 YTH N(6)-methyladenosine RNA binding protein 2 1 28736621-28769775 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054080, HPA059621 Approved Approved Cytosol Expressed in all parathyroid gland: 57.8 -TMA16 C4orf43, FLJ11184 ENSG00000198498 Translation machinery associated 16 homolog 4 163494442-163520539 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041571, HPA052688 Uncertain Validated Nucleoli Expressed in all testis: 43.5 -HLA-DRB5 ENSG00000198502 Major histocompatibility complex, class II, DR beta 5 6 32517343-32530287 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043151 Supported Tissue enhanced 0 lung: 532.0 lymph node: 405.2 -ATL1 AD-FSP, FSP1, SPG3, SPG3A ENSG00000198513 Atlastin GTPase 1 14 50532509-50633068 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027550 Approved Tissue enhanced 0 cerebral cortex: 97.2 smooth muscle: 22.1 -CNGA1 CNCG, CNCG1, CNG1, RCNC1, RCNCa, RP49 ENSG00000198515 Cyclic nucleotide gated channel alpha 1 4 47935977-48016672 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA076168 Approved Vesicles
Plasma membrane Mixed liver: 14.2 -MAFK NFE2U, P18 ENSG00000198517 V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 7 1530714-1543043 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026820, HPA060841 Approved Validated Nucleoplasm Expressed in all placenta: 36.6 -C1orf228 MGC33556, NCRNA00082, p40 ENSG00000198520 Chromosome 1 open reading frame 228 1 44674692-44725591 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA034769 Uncertain Uncertain Cytosol Tissue enhanced 0 fallopian tube: 13.4;testis: 21.5 epididymis: 5.1 -ZNF43 HTF6, KOX27, ZNF39L1 ENSG00000198521 Zinc finger protein 43 19 21804949-21852125 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA050271 Uncertain Mixed testis: 17.0 -GPN1 ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1 ENSG00000198522 GPN-loop GTPase 1 2 27628247-27651508 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036793, HPA036794, CAB037303 Uncertain Supported Nucleoplasm
Mitochondria
Cytosol Expressed in all testis: 47.2 -PLN CMD1P, PLB ENSG00000198523 Phospholamban 6 118548298-118560730 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005597, HPA026900 Supported Tissue enriched 6 heart muscle: 1486.3 smooth muscle: 266.8 -C2CD4A FAM148A, NLF1 ENSG00000198535 C2 calcium-dependent domain containing 4A 15 62066977-62070917 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed endometrium: 2.3 -ZNF28 DKFZp781D0275, KOX24 ENSG00000198538 Zinc finger protein 28 19 52797409-52857600 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed thyroid gland: 17.9 -ITGBL1 OSCP, TIED ENSG00000198542 Integrin, beta-like 1 (with EGF-like repeat domains) 13 101452593-101720856 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA005676 Uncertain Tissue enhanced 0 gallbladder: 60.1 placenta: 46.8 -ZNF511 MGC30006 ENSG00000198546 Zinc finger protein 511 10 133308475-133313162 Predicted membrane proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035360 Uncertain Expressed in all ovary: 11.4 -ZNF627 FLJ90365 ENSG00000198551 Zinc finger protein 627 19 11559374-11619135 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA049770, HPA073463 Uncertain Approved Nucleus
Nucleoli Expressed in all thyroid gland: 20.6 -KCNRG ENSG00000198553 Potassium channel regulator 13 50015254-50020922 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA001027 Uncertain Vesicles Tissue enriched 11 fallopian tube: 51.5 lung: 4.5 -WDHD1 AND-1, CHTF4, CTF4 ENSG00000198554 WD repeat and HMG-box DNA binding protein 1 14 54938950-55027105 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001122 Supported Validated Nucleoplasm Mixed testis: 9.8 -ZNF789 ENSG00000198556 Zinc finger protein 789 7 99472841-99503650 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029500, HPA050793 Uncertain Validated Nucleoplasm Mixed prostate: 13.7 -CTNND1 CTNND, KIAA0384, p120, p120cas, p120ctn ENSG00000198561 Catenin (cadherin-associated protein), delta 1 11 57753243-57819546 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003837, HPA015954, HPA015955 Supported Validated Plasma membrane Expressed in all parathyroid gland: 192.9 -DDX39B BAT1, D6S81E, UAP56 ENSG00000198563 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 6 31530219-31542448 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034012, HPA055334, HPA058450 Supported Validated Nuclear speckles Expressed in all epididymis: 44.0 -SLC34A3 FLJ38680, NPTIIc ENSG00000198569 Solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 9 137230757-137236554 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023776 Supported Group enriched 14 kidney: 11.8;small intestine: 9.2 testis: 0.7 -RD3 C1orf36, LCA12 ENSG00000198570 Retinal degeneration 3 1 211476522-211492917 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Not detected epididymis: 0.3 -SPANXC CT11.3, CTp11 ENSG00000198573 SPANX family, member C X 141241463-141242496 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046423 Uncertain Supported Nucleoplasm
Vesicles Tissue enriched 151 testis: 15.0 adipose tissue: 0.0 -SH2D1B EAT2 ENSG00000198574 SH2 domain containing 1B 1 162395266-162412138 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054791 Uncertain Tissue enhanced 0 spleen: 10.4 lung: 3.3 -ARC Arg3.1, KIAA0278 ENSG00000198576 Activity-regulated cytoskeleton-associated protein 8 142611044-142614472 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056430 Approved Vesicles
Microtubules Group enriched 7 adipose tissue: 14.1;adrenal gland: 13.4;cerebral cortex: 14.4;gallbladder: 3.3;seminal vesicle: 5.5 placenta: 1.4 -NUDT16 FLJ31265 ENSG00000198585 Nudix (nucleoside diphosphate linked moiety X)-type motif 16 3 131381671-131388830 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA060452, HPA062492 Uncertain Supported Nucleus
Nucleoli Expressed in all parathyroid gland: 54.4 -TLK1 KIAA0137, PKU-BETA ENSG00000198586 Tousled-like kinase 1 2 170990823-171231314 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016043 Approved Validated Nucleus Expressed in all parathyroid gland: 40.0 -LRBA BGL, CDC4L, LAB300, LBA ENSG00000198589 LPS-responsive vesicle trafficking, beach and anchor containing 4 150264531-151015727 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019366, HPA023597 Approved Approved Golgi apparatus
Cytosol Expressed in all parathyroid gland: 61.5 -ZNF536 KIAA0390 ENSG00000198597 Zinc finger protein 536 19 30228290-30713538 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 19.1 thyroid gland: 5.3 -MMP17 MT4-MMP ENSG00000198598 Matrix metallopeptidase 17 (membrane-inserted) 12 131828393-131851783 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 24.1 skin: 8.2 -OR2M2 OR2M2Q, OST423 ENSG00000198601 Olfactory receptor, family 2, subfamily M, member 2 1 248179986-248181029 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -BAZ1A ACF1, hACF1, WALp1, WCRF180 ENSG00000198604 Bromodomain adjacent to zinc finger domain, 1A 14 34752731-34875647 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002730 Supported Uncertain Endoplasmic reticulum Expressed in all testis: 55.8 -AKR1C4 3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581 ENSG00000198610 Aldo-keto reductase family 1, member C4 10 5195462-5218949 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044720, HPA068265 Uncertain Uncertain Nucleus
Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Tissue enriched 6 liver: 358.9 gallbladder: 64.5 -COPS8 COP9, CSN8, MGC1297, SGN8 ENSG00000198612 COP9 signalosome subunit 8 2 237085312-237100466 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036485 Uncertain Supported Nucleoplasm
Cytosol Expressed in all cerebral cortex: 116.4 -CCDC69 DKFZP434C171, FLJ13705 ENSG00000198624 Coiled-coil domain containing 69 5 151181052-151224145 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043648, HPA052896 Uncertain Approved Golgi apparatus
Plasma membrane
Actin filaments Expressed in all skeletal muscle: 113.1 -MDM4 HDMX, MDMX ENSG00000198625 MDM4, p53 regulator 1 204516379-204558120 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018919, HPA048821 Approved Supported Nucleus Expressed in all bone marrow: 37.5 -RYR2 ARVC2, ARVD2, VTSIP ENSG00000198626 Ryanodine receptor 2 (cardiac) 1 237042205-237833988 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA020028 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enriched 9 heart muscle: 68.2 cerebral cortex: 8.0 -ZNF534 FLJ25344, KRBO3 ENSG00000198633 Zinc finger protein 534 19 52429187-52452315 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 2.4 cerebral cortex: 0.9 -KLHL9 FLJ13568, KIAA1354 ENSG00000198642 Kelch-like family member 9 9 21329671-21335380 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046039, HPA059901 Approved Approved Cytosol Expressed in all thyroid gland: 26.9 -FAM3D EF7, OIT1 ENSG00000198643 Family with sequence similarity 3, member D 3 58633946-58666848 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013844 Approved Tissue enhanced 0 colon: 324.9;rectum: 492.0 salivary gland: 192.8 -NCOA6 AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP ENSG00000198646 Nuclear receptor coactivator 6 20 34689097-34825649 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004198, HPA050211 Supported Supported Nucleoplasm Expressed in all parathyroid gland: 41.8 -STK39 DCHT, SPAK ENSG00000198648 Serine threonine kinase 39 2 167954020-168248141 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046022, HPA061803, HPA062802 Supported Supported Nucleoplasm
Vesicles
Cytosol Mixed testis: 71.3 -TAT ENSG00000198650 Tyrosine aminotransferase 16 71565660-71577130 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 8 liver: 618.9 breast: 75.4 -OR8B4 OR8B4P ENSG00000198657 Olfactory receptor, family 8, subfamily B, member 4 (gene/pseudogene) 11 124423942-124424871 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA049884 Uncertain Not detected adipose tissue: 0.0 -C6orf89 BRAP, FLJ25357 ENSG00000198663 Chromosome 6 open reading frame 89 6 36871870-36928964 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012548 Uncertain Expressed in all thyroid gland: 96.8 -CALM1 CALML2, CAMI, DD132, PHKD ENSG00000198668 Calmodulin 1 (phosphorylase kinase, delta) 14 90396502-90408261 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level CAB018558, HPA044999 Supported Approved Vesicles Expressed in all cerebral cortex: 1329.9 -LPA LP ENSG00000198670 Lipoprotein, Lp(a) 6 160531483-160664259 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016072, HPA060604 Supported Tissue enriched 26 liver: 41.5 seminal vesicle: 1.6 -FAM19A2 TAFA-2 ENSG00000198673 Family with sequence similarity 19 (chemokine (C-C motif)-like), member A2 12 61708259-62279150 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 26.4 seminal vesicle: 9.9 -OR10G6 OR10G6P, OR10G6Q ENSG00000198674 Olfactory receptor, family 10, subfamily G, member 6 11 123994163-123995161 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -TTC37 KIAA0372, THES ENSG00000198677 Tetratricopeptide repeat domain 37 5 95463895-95555007 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037905 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 80.8 -TUSC1 TSG-9 ENSG00000198680 Tumor suppressor candidate 1 9 25676389-25678440 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051426 Approved Approved Nucleus
Vesicles Expressed in all testis: 16.5 -MAGEA1 CT1.1, MAGE1, MGC9326 ENSG00000198681 Melanoma antigen family A1 X 153179285-153183880 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002620 Supported Supported Cytosol Tissue enriched 73 testis: 7.2 adipose tissue: 0.0 -PAPSS2 ATPSK2 ENSG00000198682 3'-phosphoadenosine 5'-phosphosulfate synthase 2 10 87659613-87747705 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071224 Approved Mitochondria Expressed in all adrenal gland: 158.4 -SLC9A6 KIAA0267, NHE6 ENSG00000198689 Solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 X 135985424-136047269 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059445, HPA059590 Approved Supported Vesicles Tissue enhanced 0 cerebral cortex: 76.1 parathyroid gland: 17.3 -FAN1 KIAA1018, MTMR15 ENSG00000198690 FANCD2/FANCI-associated nuclease 1 15 30903852-30943108 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048198 Supported Nucleoplasm
Cytokinetic bridge
Cytosol Expressed in all prostate: 9.8 -ABCA4 ABCA4, ABCR , ARMD2, CORD3, FFM, RP19, STGD, STGD1 ENSG00000198691 ATP-binding cassette, sub-family A (ABC1), member 4 1 93992835-94121132 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 epididymis: 9.7 kidney: 4.1 -EIF1AY ENSG00000198692 Eukaryotic translation initiation factor 1A, Y-linked Y 20575725-20593154 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002561 Uncertain Approved Approved Cytosol Mixed prostate: 42.7 -MT-ND6 MTND6, NAD6, ND6 ENSG00000198695 Mitochondrially encoded NADH dehydrogenase 6 MT 14149-14673 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all heart muscle: 21512.1 -IPO9 FLJ10402, Imp9 ENSG00000198700 Importin 9 1 201829141-201884294 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059540 Approved Vesicles
Cytosol Expressed in all parathyroid gland: 30.0 -GPX6 GPXP3 ENSG00000198704 Glutathione peroxidase 6 6 28503296-28528215 Enzymes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12 epididymis: 4.1 testis: 0.3 -CEP290 3H11Ag, BBS14, CT87, FLJ13615, JBTS5, KIAA0373, LCA10, MKS4, NPHP6, POC3, rd16, SLSN6 ENSG00000198707 Centrosomal protein 290kDa 12 88049014-88142216 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB029995, HPA043918, HPA064397 Approved Supported Centrosome Mixed parathyroid gland: 21.6 -MT-CO2 CO2, COX2, MTCO2 ENSG00000198712 Mitochondrially encoded cytochrome c oxidase II MT 7586-8269 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016243, HPA051505, HPA054758 Supported Expressed in all heart muscle: 42147.3 -GLMP C1orf85, MGC31963, NCU-G1 ENSG00000198715 Glycosylated lysosomal membrane protein 1 156290089-156295689 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029121 Uncertain Expressed in all prostate: 94.9 -FAM179B KIAA0423 ENSG00000198718 Family with sequence similarity 179, member B 14 44962208-45074431 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050849, HPA053559 Uncertain Approved Nucleoplasm Expressed in all cerebral cortex: 16.7 -DLL1 ENSG00000198719 Delta-like 1 (Drosophila) 6 170282206-170306565 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed spleen: 20.3 -ANKRD13B FLJ25555 ENSG00000198720 Ankyrin repeat domain 13B 17 29589769-29614761 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051886, HPA063748 Uncertain Supported Vesicles Tissue enhanced 0 cerebral cortex: 26.0 testis: 17.6 -ECI2 ACBD2, DRS1, HCA88, PECI ENSG00000198721 Enoyl-CoA delta isomerase 2 6 4115689-4135597 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022130, HPA031626 Supported Validated Peroxisomes Expressed in all kidney: 236.6 -UNC13B hmunc13, UNC13, Unc13h2 ENSG00000198722 Unc-13 homolog B (C. elegans) 9 35161992-35405338 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024493, HPA062300 Approved Approved Nucleoplasm
Intermediate filaments
Cytosol Mixed lung: 62.3 -C19orf45 FLJ35784 ENSG00000198723 Chromosome 19 open reading frame 45 19 7492976-7508450 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA066278 Uncertain Tissue enhanced 0 testis: 17.0 seminal vesicle: 4.2 -MT-CYB COB, CYTB, MTCYB, UQCR3 ENSG00000198727 Mitochondrially encoded cytochrome b MT 14747-15887 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB032215, HPA068400 Approved Approved Mitochondria Expressed in all heart muscle: 24037.9 -LDB1 CLIM2, NLI ENSG00000198728 LIM domain binding 1 10 102107560-102120453 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034488 Approved Approved Nucleoplasm Expressed in all skin: 158.5 -PPP1R14C CPI17-like, KEPI, NY-BR-81 ENSG00000198729 Protein phosphatase 1, regulatory (inhibitor) subunit 14C 6 150143076-150250357 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 skin: 76.3;thyroid gland: 101.1 heart muscle: 51.8 -CTR9 KIAA0155, p150TSP, SH2BP1, TSBP ENSG00000198730 CTR9 homolog, Paf1/RNA polymerase II complex component 11 10750987-10779743 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061027, HPA068122 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 59.0 -SMOC1 ENSG00000198732 SPARC related modular calcium binding 1 14 69854131-70032366 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004153, CAB034427 Approved Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 136.1 testis: 64.9 -F5 ENSG00000198734 Coagulation factor V (proaccelerin, labile factor) 1 169514166-169586588 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA002036 Uncertain Approved Golgi apparatus Group enriched 11 gallbladder: 28.5;liver: 93.7;placenta: 67.7 fallopian tube: 5.8 -MSRB1 SelR, SelX, SepR, SEPX1 ENSG00000198736 Methionine sulfoxide reductase B1 16 1938210-1943326 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008650, HPA043463, HPA069557 Approved Validated Nucleoplasm Expressed in all liver: 61.6 -LRRTM3 ENSG00000198739 Leucine rich repeat transmembrane neuronal 3 10 66926006-67099830 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 5 cerebral cortex: 22.7 ovary: 4.2 -ZNF652 KIAA0924 ENSG00000198740 Zinc finger protein 652 17 49289206-49362473 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044408 Uncertain Approved Nucleus Mixed breast: 7.2 -SMURF1 KIAA1625 ENSG00000198742 SMAD specific E3 ubiquitin protein ligase 1 7 99027438-99144100 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055245 Approved Expressed in all testis: 45.9 -SLC5A3 SMIT, SMIT1 ENSG00000198743 Solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 21 34073570-34106260 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA029791 Approved Plasma membrane
Cytosol Tissue enhanced 0 thyroid gland: 42.0 kidney: 32.9 -GPATCH3 FLJ12455, GPATC3 ENSG00000198746 G patch domain containing 3 1 26890488-26900466 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA032078, HPA054973 Approved Approved Nucleoplasm
Cytosol Expressed in all bone marrow: 15.3 -CDC42BPB KIAA1124, MRCKB ENSG00000198752 CDC42 binding protein kinase beta (DMPK-like) 14 102932379-103057462 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022821 Approved Approved Nuclear speckles
Cytosol Expressed in all cerebral cortex: 75.3 -PLXNB3 PLEXB3, PLEXR, PLXN6 ENSG00000198753 Plexin B3 X 153764196-153779346 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048046 Supported Tissue enhanced 0 cerebral cortex: 67.4 adrenal gland: 19.7 -OXCT2 FKSG25, FLJ00030, SCOT-T ENSG00000198754 3-oxoacid CoA transferase 2 1 39769523-39771348 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 12 testis: 37.5 heart muscle: 3.2 -RPL10A Csa-19, L10A, NEDD6 ENSG00000198755 Ribosomal protein L10a 6 35468408-35470785 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053803 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all ovary: 3913.5 -COLGALT2 C1orf17, GLT25D2, KIAA0584 ENSG00000198756 Collagen beta(1-O)galactosyltransferase 2 1 183929854-184037729 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031749, HPA031750 Approved Approved Nucleus
Vesicles Tissue enriched 5 cerebral cortex: 46.5 adrenal gland: 8.5 -EPS8L3 FLJ21522, MGC16817 ENSG00000198758 EPS8-like 3 1 109750080-109764027 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030998 Approved Approved Vesicles Group enriched 6 colon: 76.3;duodenum: 156.3;gallbladder: 60.0;rectum: 87.4;small intestine: 170.4;stomach: 54.0 appendix: 15.8 -EGFL6 MAEG ENSG00000198759 EGF-like-domain, multiple 6 X 13569605-13633575 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA001838 Approved Tissue enriched 34 placenta: 913.7 lung: 26.8 -MT-ND2 MTND2, NAD2, ND2 ENSG00000198763 Mitochondrially encoded NADH dehydrogenase 2 MT 4470-5511 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all heart muscle: 25403.8 -SYCP1 CT8, HOM-TES-14, SCP1 ENSG00000198765 Synaptonemal complex protein 1 1 114854803-114995370 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021083 Supported Tissue enriched 98 testis: 72.2 breast: 0.7 -APCDD1L FLJ90166 ENSG00000198768 Adenomatosis polyposis coli down-regulated 1-like 20 58459101-58515131 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA067015 Uncertain Uncertain Mitochondria Tissue enhanced 0 breast: 6.5;salivary gland: 11.7 kidney: 2.9 -RCSD1 CapZIP, MGC21854, MK2S4 ENSG00000198771 RCSD domain containing 1 1 167630093-167706249 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016597 Supported Uncertain Nucleoplasm
Plasma membrane Tissue enhanced 0 lymph node: 108.5 tonsil: 74.2 -RASSF9 P-CIP1, PAMCI ENSG00000198774 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 12 85800697-85836570 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039428, HPA039678 Approved Mixed fallopian tube: 10.1 -FAM169A KIAA0888 ENSG00000198780 Family with sequence similarity 169, member A 5 74777574-74866951 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041574 Supported Supported Nuclear membrane
Cytosol Tissue enhanced 0 cerebral cortex: 29.3;testis: 25.1 epididymis: 20.5 -ZNF830 CCDC16, MGC20398, OMCG1 ENSG00000198783 Zinc finger protein 830 17 34961530-34963775 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA024754, HPA027211 Supported Validated Nucleoplasm Expressed in all spleen: 16.9 -GRIN3A GluN3A ENSG00000198785 Glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 9 101569353-101738580 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 5 cerebral cortex: 12.4;cervix, uterine: 2.5 seminal vesicle: 1.4 -MT-ND5 MTND5, NAD5, ND5 ENSG00000198786 Mitochondrially encoded NADH dehydrogenase 5 MT 12337-14148 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all heart muscle: 13033.0 -CNOT7 CAF1 ENSG00000198791 CCR4-NOT transcription complex, subunit 7 8 17224964-17246878 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA069543 Supported Nuclear bodies Expressed in all parathyroid gland: 109.5 -TMEM184B C22orf5, DKFZP586A1024, FM08, HS5O6A ENSG00000198792 Transmembrane protein 184B 22 38219291-38273034 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA024076 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all cerebral cortex: 57.5 -MTOR FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 ENSG00000198793 Mechanistic target of rapamycin (serine/threonine kinase) 1 11106535-11262507 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB069425, HPA071227 Approved Approved Vesicles
Cytosol Expressed in all testis: 62.0 -SCAMP5 MGC24969 ENSG00000198794 Secretory carrier membrane protein 5 15 74957219-75021496 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046645 Approved Tissue enhanced 0 cerebral cortex: 276.3 parathyroid gland: 80.7 -ZNF521 EHZF, Evi3 ENSG00000198795 Zinc finger protein 521 18 25061926-25352190 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA023056, HPA023849 Approved Approved Nucleoplasm Mixed spleen: 29.4 -ALPK2 HAK ENSG00000198796 Alpha-kinase 2 18 58481247-58628957 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA027377, HPA027976, HPA028084, HPA029801 Uncertain Approved Cytosol Tissue enhanced 0 heart muscle: 28.3;skeletal muscle: 14.1 lymph node: 6.9 -BRINP2 DBCCR1L2, FAM5B ENSG00000198797 Bone morphogenetic protein/retinoic acid inducible neural-specific 2 1 177171497-177282422 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA050681, HPA061920 Uncertain Approved Nucleoli
Vesicles Group enriched 9 adrenal gland: 11.5;cerebral cortex: 35.5 testis: 2.4 -MAGEB3 CT3.5 ENSG00000198798 Melanoma antigen family B3 X 30230436-30237492 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA072203 Approved Group enriched 160 epididymis: 22.5;testis: 9.5 parathyroid gland: 0.0 -LRIG2 KIAA0806 ENSG00000198799 Leucine-rich repeats and immunoglobulin-like domains 2 1 113073209-113132260 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA015538 Uncertain Supported Nucleus
Golgi apparatus Mixed parathyroid gland: 5.6 -MT-CO1 COI, COX1, MTCO1 ENSG00000198804 Mitochondrially encoded cytochrome c oxidase I MT 5904-7445 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016241, HPA069328 Supported Supported Mitochondria Expressed in all heart muscle: 79793.3 -PNP NP, PUNP ENSG00000198805 Purine nucleoside phosphorylase 14 20468954-20477094 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001625 Supported Expressed in all epididymis: 686.0 -PAX9 ENSG00000198807 Paired box 9 14 36657568-36679715 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA038462 Uncertain Approved Nucleoplasm
Mitochondria Group enriched 8 esophagus: 56.3;parathyroid gland: 101.3;salivary gland: 21.8 tonsil: 7.8 -LRRC10 HRLRRP, LRRC10A ENSG00000198812 Leucine rich repeat containing 10 12 69608564-69611162 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 27 heart muscle: 21.6 lymph node: 0.8 -GK GK1, GKD ENSG00000198814 Glycerol kinase X 30653359-30731456 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060687 Approved Tissue enhanced 0 kidney: 110.2;small intestine: 100.8 duodenum: 89.7 -FOXJ3 KIAA1041 ENSG00000198815 Forkhead box J3 1 42176539-42335877 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067284 Approved Nucleoplasm
Nuclear speckles
Vesicles Expressed in all parathyroid gland: 39.5 -ZNF358 FLJ10390, ZFEND ENSG00000198816 Zinc finger protein 358 19 7515292-7521026 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030887, HPA063624 Approved Approved Nucleus Expressed in all ovary: 85.4 -SFT2D1 C6orf83, MGC19825, pRGR1 ENSG00000198818 SFT2 domain containing 1 6 166319728-166342591 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014677 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all prostate: 77.5 -CD247 CD3H, CD3Q, CD3Z ENSG00000198821 CD247 molecule 1 167430640-167518610 CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004651, HPA008750 Supported Tissue enhanced 0 lymph node: 66.0;spleen: 49.4 tonsil: 34.9 -GRM3 GPRC1C, mGlu3, MGLUR3 ENSG00000198822 Glutamate receptor, metabotropic 3 7 86643914-86864884 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 34 cerebral cortex: 62.5 testis: 1.8 -CHAMP1 C13orf8, CAMP, CHAMP, ZNF828 ENSG00000198824 Chromosome alignment maintaining phosphoprotein 1 13 114314513-114327328 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006623, HPA008900 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all lymph node: 19.6 -INPP5F hSac2, KIAA0966, SAC2 ENSG00000198825 Inositol polyphosphate-5-phosphatase F 10 119726097-119829278 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 112.6 -ARHGAP11A KIAA0013 ENSG00000198826 Rho GTPase activating protein 11A 15 32615144-32639949 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040419, HPA040830 Approved Approved Nucleoli
Cytosol Mixed lymph node: 13.9 -SUCNR1 GPR91 ENSG00000198829 Succinate receptor 1 3 151873643-151884619 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB022745 Uncertain Tissue enhanced 0 kidney: 42.0 thyroid gland: 15.8 -HMGN2 HMG17 ENSG00000198830 High mobility group nucleosomal binding domain 2 1 26472450-26475972 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018371, HPA077364 Supported Supported Nucleus Expressed in all bone marrow: 784.4 -SELM ENSG00000198832 Selenoprotein M 22 31104772-31120069 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB008667, HPA019601 Approved Approved Nucleoplasm
Cytosol Expressed in all seminal vesicle: 198.4 -UBE2J1 CGI-76, HSPC153, NCUBE1, UBC6 ENSG00000198833 Ubiquitin-conjugating enzyme E2, J1 6 89326625-89352848 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003509, CAB073419 Supported Expressed in all lymph node: 103.6 -GJC2 CX46.6, CX47, GJA12, SPG44 ENSG00000198835 Gap junction protein, gamma 2, 47kDa 1 228149852-228159826 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 11.6 endometrium: 3.6 -OPA1 FLJ12460, KIAA0567, MGM1, NPG, NTG ENSG00000198836 Optic atrophy 1 (autosomal dominant) 3 193593144-193697823 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036926, HPA036927 Supported Supported Nucleoplasm
Mitochondria Expressed in all cerebral cortex: 56.4 -DENND4B KIAA0476 ENSG00000198837 DENN/MADD domain containing 4B 1 153929501-153946696 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040188 Approved Nucleus
Golgi apparatus Expressed in all spleen: 40.9 -RYR3 ENSG00000198838 Ryanodine receptor 3 15 33310945-33866121 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062004 Uncertain Vesicles Tissue enhanced 0 parathyroid gland: 44.5 skeletal muscle: 13.3 -ZNF277 NRIF4, ZNF277P ENSG00000198839 Zinc finger protein 277 7 112206588-112343096 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA027307 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all thyroid gland: 33.4 -MT-ND3 MTND3, NAD3, ND3 ENSG00000198840 Mitochondrially encoded NADH dehydrogenase 3 MT 10059-10404 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063296 Supported Approved Cytosol Expressed in all heart muscle: 30137.8 -KTI12 MGC20419, SBBI81, TOT4 ENSG00000198841 KTI12 chromatin associated homolog 1 52032103-52033816 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031204, HPA031205 Approved Mixed ovary: 11.5 -DUSP27 ENSG00000198842 Dual specificity phosphatase 27 (putative) 1 167094045-167129165 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012608, HPA012912 Uncertain Approved Nucleoplasm Group enriched 15 heart muscle: 39.9;skeletal muscle: 39.7 placenta: 2.6 -SELT ENSG00000198843 Selenoprotein T 3 150602875-150630445 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039780 Approved Expressed in all thyroid gland: 108.8 -ARHGEF15 ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF ENSG00000198844 Rho guanine nucleotide exchange factor (GEF) 15 17 8310241-8322516 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044443, HPA063495 Uncertain Supported Plasma membrane Tissue enhanced 0 adipose tissue: 37.1 lung: 30.7 -TOX KIAA0808, TOX1 ENSG00000198846 Thymocyte selection-associated high mobility group box 8 58805418-59119208 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA018322, HPA073241 Supported Approved Nucleus
Nucleoli fibrillar center Mixed lymph node: 21.3 -CES1 CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1 ENSG00000198848 Carboxylesterase 1 16 55802851-55833337 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012023, HPA046717 Supported Validated Endoplasmic reticulum Group enriched 7 gallbladder: 400.5;liver: 1099.6;lung: 229.6 adipose tissue: 79.7 -CD3E ENSG00000198851 CD3e molecule, epsilon (CD3-TCR complex) 11 118304545-118316175 CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000010, HPA040957, HPA043955, CAB072863, CAB072864 Supported Tissue enhanced 0 lymph node: 203.4;tonsil: 118.2 appendix: 97.3 -RUSC2 KIAA0375 ENSG00000198853 RUN and SH3 domain containing 2 9 35490127-35561898 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021297 Uncertain Expressed in all cerebral cortex: 48.7 -C1orf68 LEP7, XP32 ENSG00000198854 Chromosome 1 open reading frame 68 1 152719522-152720470 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040836 Uncertain Tissue enriched 14 skin: 807.2 breast: 56.7 -FICD HIP13, HYPE ENSG00000198855 FIC domain containing 12 108515185-108525837 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021390, HPA071134 Approved Approved Nucleus Mixed thyroid gland: 17.6 -OSTC DC2 ENSG00000198856 Oligosaccharyltransferase complex subunit (non-catalytic) 4 108650584-108667820 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065174 Approved Nucleoplasm Expressed in all epididymis: 211.5 -R3HDM4 C19orf22, MGC16353 ENSG00000198858 R3H domain containing 4 19 896503-913245 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043025, HPA048638 Uncertain Approved Nucleus
Cytosol Expressed in all appendix: 69.6 -TSEN15 C1orf19 ENSG00000198860 TSEN15 tRNA splicing endonuclease subunit 1 184051677-184074212 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029237 Approved Approved Nucleus
Nucleoli Expressed in all thyroid gland: 34.7 -LTN1 C21orf10, C21orf98, FLJ11053, KIAA0714, LISTERIN, RNF160, ZNF294 ENSG00000198862 Listerin E3 ubiquitin protein ligase 1 21 28928144-28992956 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029143, CAB034164, HPA055604 Uncertain Validated Cytosol Expressed in all placenta: 26.4 -RUNDC1 DKFZp761H0421 ENSG00000198863 RUN domain containing 1 17 42980565-42993690 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023726 Uncertain Approved Nuclear speckles
Cytosol Expressed in all fallopian tube: 23.3 -CCDC152 LOC100129792 ENSG00000198865 Coiled-coil domain containing 152 5 42756801-42802360 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036240 Approved Approved Nucleoplasm
Cytosol Mixed liver: 16.2 -STKLD1 C9orf96, MGC43306, SGK071 ENSG00000198870 Serine/threonine kinase-like domain containing 1 9 133376367-133406096 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029902 Uncertain Tissue enriched 14 testis: 5.7 epididymis: 0.3 -GRK5 GPRK5 ENSG00000198873 G protein-coupled receptor kinase 5 10 119207589-119459742 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB025579, HPA046838 Approved Approved Nuclear membrane
Nuclear speckles
Plasma membrane Expressed in all parathyroid gland: 77.1 -TYW1 FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W ENSG00000198874 TRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 7 66995173-67239519 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA013568, HPA014118, HPA015535, HPA043136, HPA047029, HPA047052, HPA052097 Approved Approved Nucleus
Nucleoli Expressed in all parathyroid gland: 22.9 -DCAF12 CT102, DKFZP434O125, KIAA1892, MGC1058, TCC52, WDR40A ENSG00000198876 DDB1 and CUL4 associated factor 12 9 34086387-34127399 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062279 Approved Expressed in all testis: 112.9 -OR5D13 ENSG00000198877 Olfactory receptor, family 5, subfamily D, member 13 (gene/pseudogene) 11 55773438-55774382 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -SFMBT2 KIAA1617 ENSG00000198879 Scm-like with four mbt domains 2 10 7158624-7411486 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035447, HPA035448 Uncertain Supported Nuclear speckles Mixed parathyroid gland: 15.1 -ASB12 FLJ39577 ENSG00000198881 Ankyrin repeat and SOCS box containing 12 X 64224196-64230631 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049542 Uncertain Tissue enriched 14 skeletal muscle: 30.7 fallopian tube: 2.2 -PNMA5 KIAA1934 ENSG00000198883 Paraneoplastic Ma antigen family member 5 X 152988824-152994127 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044690 Supported Group enriched 20 cerebral cortex: 8.1;testis: 16.2 spleen: 0.6 -ITPRIPL1 KIAA1754L ENSG00000198885 Inositol 1,4,5-trisphosphate receptor interacting protein-like 1 2 96325331-96330517 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017985 Uncertain Tissue enriched 6 testis: 27.3 lymph node: 4.9 -MT-ND4 LHON, MTND4, NAD4, ND4 ENSG00000198886 Mitochondrially encoded NADH dehydrogenase 4 MT 10760-12137 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053928 Approved Expressed in all heart muscle: 38133.1 -SMC5 KIAA0594, SMC5L1 ENSG00000198887 Structural maintenance of chromosomes 5 9 70258962-70354888 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054900 Supported Supported Nuclear speckles Expressed in all ovary: 30.8 -MT-ND1 MTND1, NAD1, ND1 ENSG00000198888 Mitochondrially encoded NADH dehydrogenase 1 MT 3307-4262 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033779 Approved Expressed in all skeletal muscle: 23823.0 -DCAF12L1 KIAA1892L, WDR40B ENSG00000198889 DDB1 and CUL4 associated factor 12-like 1 X 126549383-126552851 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044737, HPA048981, HPA053138 Approved Approved Cytosol Tissue enhanced 0 epididymis: 5.8;testis: 11.4 fallopian tube: 4.0 -PRMT6 FLJ10559, HRMT1L6 ENSG00000198890 Protein arginine methyltransferase 6 1 107056679-107059294 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059424 Approved Supported Nucleus
Nucleoli Mixed parathyroid gland: 17.2 -SHISA4 C1orf40, hShisa4, TMEM58 ENSG00000198892 Shisa family member 4 1 201888680-201892306 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA061273 Uncertain Group enriched 5 adrenal gland: 23.6;cerebral cortex: 45.5;skeletal muscle: 94.5 heart muscle: 10.8 -CIPC KIAA1737 ENSG00000198894 CLOCK-interacting pacemaker 14 77098097-77117287 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA000644 Supported Nucleus
Nucleoli
Cytosol Expressed in all cerebral cortex: 54.5 -CAPZA2 CAPPA2, CAPZ ENSG00000198898 Capping protein (actin filament) muscle Z-line, alpha 2 7 116811070-116922049 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007470, HPA007643 Uncertain Approved Endoplasmic reticulum
Cytosol Expressed in all smooth muscle: 41.9 -MT-ATP6 ATP6, ATPase-6, MTATP6, RP, Su6m ENSG00000198899 Mitochondrially encoded ATP synthase 6 MT 8527-9207 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all heart muscle: 40782.8 -TOP1 ENSG00000198900 Topoisomerase (DNA) I 20 41028818-41124487 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009058, HPA019039 Supported Supported Nucleus
Nucleoli fibrillar center Expressed in all lymph node: 71.8 -PRC1 ASE1 ENSG00000198901 Protein regulator of cytokinesis 1 15 90966038-90995629 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034521 Supported Approved Nucleoplasm
Plasma membrane
Microtubules Expressed in all testis: 99.7 -BHLHB9 GASP3, KIAA1701, p60TRP ENSG00000198908 Basic helix-loop-helix domain containing, class B, 9 X 102720688-102753540 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA000887 Approved Cytosol Tissue enhanced 0 cerebral cortex: 18.8 parathyroid gland: 8.3 -MAP3K3 MAPKKK3, MEKK3 ENSG00000198909 Mitogen-activated protein kinase kinase kinase 3 17 63622415-63696303 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB007764, HPA035410, HPA035411 Uncertain Approved Nucleoplasm Expressed in all spleen: 42.3 -L1CAM CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1 ENSG00000198910 L1 cell adhesion molecule X 153861514-153909223 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005830, CAB010896 Approved Approved Nucleoplasm
Plasma membrane Tissue enhanced 0 adrenal gland: 36.2;cerebral cortex: 67.1 seminal vesicle: 12.7 -SREBF2 bHLHd2, SREBP2 ENSG00000198911 Sterol regulatory element binding transcription factor 2 22 41833079-41907308 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031962, HPA031963 Approved Supported Nucleoplasm
Vesicles
Mitochondria Expressed in all cerebral cortex: 118.8 -C1orf174 RP13-531C17.2 ENSG00000198912 Chromosome 1 open reading frame 174 1 3889125-3900293 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008270, HPA065778 Approved Validated Nucleus Expressed in all fallopian tube: 17.3 -POU3F3 BRN1, OTF8 ENSG00000198914 POU class 3 homeobox 3 2 104855511-104860471 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA052792, HPA056039, HPA067151 Supported Supported Nucleus Group enriched 51 cerebral cortex: 36.6;epididymis: 34.9;kidney: 28.3;seminal vesicle: 17.2 skin: 0.5 -RASGEF1A CG4853, FLJ37817 ENSG00000198915 RasGEF domain family, member 1A 10 43194535-43266919 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035593 Approved Approved Golgi apparatus Tissue enhanced 0 cerebral cortex: 22.7 parathyroid gland: 12.5 -C9orf114 CENP-32, HSPC109 ENSG00000198917 Chromosome 9 open reading frame 114 9 128819651-128829821 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022990 Approved Nucleus
Nucleoli Expressed in all lymph node: 22.3 -RPL39 L39, RPL39P42 ENSG00000198918 Ribosomal protein L39 X 119786504-119791643 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047105 Uncertain Expressed in all breast: 5335.3 -DZIP3 hRUL138, PPP1R66 ENSG00000198919 DAZ interacting zinc finger protein 3 3 108589682-108694846 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035066, HPA049232 Approved Approved Vesicles Expressed in all testis: 65.8 -KIAA0753 ENSG00000198920 KIAA0753 17 6578148-6640927 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023057, HPA023494 Supported Validated Centrosome
Cytosol Mixed parathyroid gland: 32.5 -DCLRE1A hSNM1, KIAA0086, PSO2, SNM1 ENSG00000198924 DNA cross-link repair 1A 10 113834725-113854383 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036907 Approved Supported Nucleoplasm
Nucleoli fibrillar center Mixed parathyroid gland: 13.1 -ATG9A APG9L1, FLJ22169 ENSG00000198925 Autophagy related 9A 2 219209772-219229717 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059551 Uncertain Supported Vesicles Expressed in all testis: 112.6 -NOS1AP CAPON, KIAA0464 ENSG00000198929 Nitric oxide synthase 1 (neuronal) adaptor protein 1 162069774-162370475 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018582, HPA030066, HPA055561 Approved Approved Nucleus
Vesicles Tissue enriched 6 cerebral cortex: 23.5 adrenal gland: 3.8 -CSAG1 CSAGE, CT24.1 ENSG00000198930 Chondrosarcoma associated gene 1 X 152727484-152733735 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 2.2 lymph node: 0.8 -APRT ENSG00000198931 Adenine phosphoribosyltransferase 16 88809339-88811944 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026681 Approved Supported Nucleoplasm
Cytosol Expressed in all skin: 112.4 -GPRASP1 GASP, GASP1 ENSG00000198932 G protein-coupled receptor associated sorting protein 1 X 102651366-102659083 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000161, HPA031061 Uncertain Supported Cytosol Mixed cerebral cortex: 65.0 -TBKBP1 KIAA0775, ProSAPiP2 ENSG00000198933 TBK1 binding protein 1 17 47694081-47712050 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062347, HPA064856 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 33.0 -MAGEE1 DAMAGE, KIAA1587 ENSG00000198934 Melanoma antigen family E1 X 76427724-76431353 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA003047 Approved Approved Cytokinetic bridge
Cytosol Tissue enhanced 0 cerebral cortex: 29.9 parathyroid gland: 14.0 -CCDC167 C6orf129, dJ153P14.2 ENSG00000198937 Coiled-coil domain containing 167 6 37482920-37499922 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045215 Uncertain Approved Cytosol Expressed in all tonsil: 57.5 -MT-CO3 CO3, COIII, COX3, MTCO3 ENSG00000198938 Mitochondrially encoded cytochrome c oxidase III MT 9207-9990 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042788 Approved Approved Nucleoplasm Expressed in all heart muscle: 56545.8 -ZFP2 FLJ21628, ZNF751 ENSG00000198939 ZFP2 zinc finger protein 5 178895894-178933212 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA023364 Uncertain Mixed testis: 7.8 -SOWAHA ANKRD43 ENSG00000198944 Sosondowah ankyrin repeat domain family member A 5 132813587-132816797 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA064621 Approved Tissue enhanced 0 duodenum: 40.8;small intestine: 47.6 cerebral cortex: 22.2 -L3MBTL3 KIAA1798 ENSG00000198945 L(3)mbt-like 3 (Drosophila) 6 130013699-130141451 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044382, HPA053035 Approved Validated Nucleus
Nucleoli Mixed endometrium: 18.5 -DMD BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85 ENSG00000198947 Dystrophin X 31097677-33339441 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000119, HPA002725, HPA023885 Supported Mixed seminal vesicle: 54.1 -MFAP3L KIAA0626, NYD-sp9 ENSG00000198948 Microfibrillar-associated protein 3-like 4 169986597-170033031 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA017986, HPA077490 Approved Supported Plasma membrane Tissue enhanced 0 testis: 73.6 epididymis: 46.9 -NAGA D22S674 ENSG00000198951 N-acetylgalactosaminidase, alpha- 22 42058354-42070842 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000649 Supported Expressed in all parathyroid gland: 62.5 -SMG5 EST1B, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5 ENSG00000198952 SMG5 nonsense mediated mRNA decay factor 1 156249224-156282825 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072651 Supported Cytoplasmic bodies Expressed in all parathyroid gland: 74.7 -KIF1BP DKFZP586B0923, KBP, KIAA1279, TTC20 ENSG00000198954 KIF1 binding protein 10 68988721-69016982 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035538, HPA035539 Uncertain Expressed in all parathyroid gland: 55.6 -TGM2 TGC ENSG00000198959 Transglutaminase 2 20 38127387-38166578 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002598, HPA021019, HPA029518 Approved Approved Plasma membrane
Cytosol Tissue enhanced 0 cervix, uterine: 456.8 placenta: 317.8 -ARMCX6 FLJ20811, GASP10 ENSG00000198960 Armadillo repeat containing, X-linked 6 X 101615118-101618001 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA043030, HPA048125 Approved Supported Nucleus
Nuclear membrane
Cytosol Expressed in all parathyroid gland: 33.6 -PJA2 KIAA0438, Neurodap1, RNF131 ENSG00000198961 Praja ring finger 2, E3 ubiquitin protein ligase 5 109334709-109409994 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040347, HPA057636 Supported Supported Intermediate filaments Expressed in all cerebral cortex: 255.1 -RORB NR1F2, ROR-BETA, RZRB ENSG00000198963 RAR-related orphan receptor B 9 74497365-74693177 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008393 Uncertain Approved Nucleus Tissue enhanced 0 cerebral cortex: 12.6;cervix, uterine: 14.0 prostate: 7.6 -SGMS1 MGC17342, MOB, SMS1, TMEM23 ENSG00000198964 Sphingomyelin synthase 1 10 50305586-50625163 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045191 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 114.4 -OR10R2 OR10R2Q ENSG00000198965 Olfactory receptor, family 10, subfamily R, member 2 1 158479878-158480885 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA059775, HPA060399 Uncertain Not detected thyroid gland: 0.1 -OR10Z1 ENSG00000198967 Olfactory receptor, family 10, subfamily Z, member 1 1 158606439-158607380 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA058072 Uncertain Not detected epididymis: 0.0 -ZNF525 KIAA1979 ENSG00000203326 Zinc finger protein 525 19 53330675-53392217 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA047105 Uncertain Mixed parathyroid gland: 20.6 -INF2 C14orf151, C14orf173, MGC13251 ENSG00000203485 Inverted formin, FH2 and WH2 domain containing 14 104689606-104722535 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000724 Approved Approved Nuclear bodies
Endoplasmic reticulum Expressed in all stomach: 56.6 -RP11-176H8.1 ENSG00000203546 14 31334312-31457441 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adipose tissue: 1.1 skeletal muscle: 0.4 -GP1BB CD42c ENSG00000203618 Glycoprotein Ib (platelet), beta polypeptide 22 19722945-19724771 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 skin: 2.7 spleen: 0.4 -OR2T5 ENSG00000203661 Olfactory receptor, family 2, subfamily T, member 5 1 248488589-248489536 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -OR2L2 HSHTPCRH07, HTPCRH07, OR2L12, OR2L4P ENSG00000203663 Olfactory receptor, family 2, subfamily L, member 2 1 248038268-248039206 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 7 testis: 2.5 spleen: 0.3 -EFCAB2 CFAP200, DRC8, MGC12458 ENSG00000203666 EF-hand calcium binding domain 2 1 244969705-245127164 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031206, HPA031207 Approved Approved Plasma membrane
Cytosol Expressed in all fallopian tube: 57.4 -COX20 FAM36A, FLJ43269 ENSG00000203667 COX20 cytochrome c oxidase assembly factor 1 244835322-244845057 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043617, HPA045490 Approved Validated Mitochondria Expressed in all adrenal gland: 46.7 -CHML REP-2 ENSG00000203668 Choroideremia-like (Rab escort protein 2) 1 241628853-241635930 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029627, HPA029628, HPA062967 Supported Supported Nucleoplasm
Cytosol Mixed placenta: 17.0 -C1orf95 DKFZp761P211 ENSG00000203685 Chromosome 1 open reading frame 95 1 226548800-226609214 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 35.8 smooth muscle: 8.3 -TCP10 ENSG00000203690 T-complex 10 6 167357031-167384510 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044709 Approved Tissue enriched 14 testis: 14.2 small intestine: 1.0 -CAPN8 nCL-2 ENSG00000203697 Calpain 8 1 223538007-223665734 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA073939 Approved Nucleoplasm
Nuclear membrane
Vesicles Tissue enriched 8 stomach: 288.4 rectum: 37.8 -TATDN3 ENSG00000203705 TatD DNase domain containing 3 1 212791828-212816626 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032092 Approved Approved Nucleoplasm
Golgi apparatus
Focal adhesion sites Expressed in all cerebral cortex: 22.2 -CR1 CD35, KN ENSG00000203710 Complement component (3b/4b) receptor 1 (Knops blood group) 1 207496147-207640647 Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002491, CAB016271, HPA042455, HPA043579, HPA049348 Supported Tissue enhanced 0 appendix: 38.5;spleen: 34.2 lymph node: 23.7 -RAET1G ULBP5 ENSG00000203722 Retinoic acid early transcript 1G 6 149916878-149923121 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062673 Approved Vesicles Tissue enhanced 0 adrenal gland: 8.3;esophagus: 9.6 skin: 3.4 -C1orf53 ENSG00000203724 Chromosome 1 open reading frame 53 1 197902647-197907367 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA065352 Approved Vesicles
Aggresome Mixed adrenal gland: 6.3 -SAMD5 dJ875H10.1 ENSG00000203727 Sterile alpha motif domain containing 5 6 147508927-147737547 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA067811 Uncertain Supported Vesicles Tissue enhanced 0 parathyroid gland: 22.2 placenta: 18.0 -TEDDM1 EDDM9, Epdd1, HE9, TMEM45C ENSG00000203730 Transmembrane epididymal protein 1 1 182398117-182400616 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 422 epididymis: 705.5 seminal vesicle: 1.6 -GJE1 CX23 ENSG00000203733 Gap junction protein, epsilon 1, 23kDa 6 142133090-142135151 Predicted membrane proteins No evidence No evidence No evidence HPA014916 Uncertain Not detected testis: 0.1 -ECT2L ARHGEF32, C6orf91, FBXO49, LFDH ENSG00000203734 Epithelial cell transforming 2 like 6 138795926-138904070 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035488 Uncertain Tissue enriched 6 fallopian tube: 18.0 lung: 2.7 -GPR52 ENSG00000203737 G protein-coupled receptor 52 1 174448111-174449198 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028575 Uncertain Tissue enriched 7 cerebral cortex: 2.7 bone marrow: 0.3 -METTL11B C1orf184, HOMT1B ENSG00000203740 Methyltransferase like 11B 1 170146001-170167790 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA028049 Uncertain Tissue enhanced 0 heart muscle: 1.6 skeletal muscle: 0.4 -FCGR3A CD16, CD16a, FCG3, FCGR3 ENSG00000203747 Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1 161541759-161550737 CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032435, HPA055431 Supported Expressed in all spleen: 427.3 -TMEM244 bA174C7.4, C6orf191 ENSG00000203756 Transmembrane protein 244 6 129831244-129861547 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA045247 Uncertain Tissue enhanced 0 cerebral cortex: 1.7 lymph node: 0.6 -OR6K3 ENSG00000203757 Olfactory receptor, family 6, subfamily K, member 3 1 158717168-158718163 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA055949 Uncertain Not detected bone marrow: 0.8 -CENPW C6orf173, CUG2 ENSG00000203760 Centromere protein W 6 126340174-126348875 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA067285 Supported Nucleoplasm Mixed testis: 51.6 -SPRN bA108K14.1, FLJ41197, Shadoo, Sprn ENSG00000203772 Shadow of prion protein homolog (zebrafish) 10 133420666-133424572 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 8 cerebral cortex: 24.9 testis: 3.0 -FAM229B C6orf225, DKFZp586F0922, LOC619208 ENSG00000203778 Family with sequence similarity 229, member B 6 112087599-112102790 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA036068 Approved Nucleus
Nucleoli
Golgi apparatus Tissue enriched 6 testis: 538.0 fallopian tube: 84.2 -FANK1 ENSG00000203780 Fibronectin type III and ankyrin repeat domains 1 10 125896539-126009592 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA037557, HPA038413 Uncertain Supported Nucleoplasm Group enriched 5 fallopian tube: 54.6;testis: 92.1 epididymis: 14.0 -LOR ENSG00000203782 Loricrin 1 153259700-153262122 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 16 skin: 532.9 breast: 32.5 -PRR9 ENSG00000203783 Proline rich 9 1 153217584-153219317 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 5 testis: 2.7 breast: 0.5 -LELP1 ENSG00000203784 Late cornified envelope-like proline-rich 1 1 153203443-153205120 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA070231 Supported Tissue enriched 2723 testis: 779.6 seminal vesicle: 0.2 -SPRR2E ENSG00000203785 Small proline-rich protein 2E 1 153093135-153106184 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 18 esophagus: 2014.8;skin: 804.5;tonsil: 477.6 breast: 60.5 -KPRP C1orf45 ENSG00000203786 Keratinocyte proline-rich protein 1 152759561-152762052 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031988, HPA031990 Supported Tissue enriched 20 skin: 268.1 breast: 13.7 -METTL10 C10orf138, Em:AC068896.3 ENSG00000203791 Methyltransferase like 10 10 124748149-124791870 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050138 Approved Approved Nucleoplasm
Nuclear bodies Mixed thyroid gland: 15.0 -FAM24A AC073585.4 ENSG00000203795 Family with sequence similarity 24, member A 10 122910701-122913111 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA052490 Uncertain Tissue enriched 330 testis: 32.9 epididymis: 0.0 -DDO ENSG00000203797 D-aspartate oxidase 6 110391771-110415562 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037525, HPA037526 Supported Supported Cytosol Tissue enhanced 0 parathyroid gland: 24.0 heart muscle: 11.7 -PLPP4 DPPL2, PPAPDC1, PPAPDC1A ENSG00000203805 Phospholipid phosphatase 4 10 120456954-120589855 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045188 Approved Approved Nucleus
Nucleoli Tissue enhanced 0 cerebral cortex: 17.2;gallbladder: 10.4;testis: 12.7 kidney: 7.7 -HIST2H3C H3, H3.2, H3/m, H3F2, H3FM, MGC9629 ENSG00000203811 Histone cluster 2, H3c 1 149839538-149841193 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Not detected cerebral cortex: 0.9 -HIST2H2AA3 H2A.2, H2A/q, H2AFO, HIST2H2AA ENSG00000203812 Histone cluster 2, H2aa3 1 149842188-149842736 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enhanced 0 bone marrow: 112.5;prostate: 102.0 spleen: 43.0 -HIST2H2BF ENSG00000203814 Histone cluster 2, H2bf 1 149782689-149812373 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB007814, HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed ovary: 24.3 -HIST2H3PS2 p06 ENSG00000203818 Histone cluster 2, H3, pseudogene 2 1 143905556-143905966 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Tissue enhanced 0 adrenal gland: 8.5;spleen: 7.9 ovary: 5.8 -PNLIPRP3 ENSG00000203837 Pancreatic lipase-related protein 3 10 116427867-116477957 Enzymes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046202, HPA052009 Uncertain Tissue enhanced 0 breast: 11.8;skin: 5.4 esophagus: 1.8 -HIST2H3A H3/n, H3/o ENSG00000203852 Histone cluster 2, H3a 1 149852619-149854274 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Not detected cerebral cortex: 0.9 -HSD3B1 HSD3B, HSDB3, SDR11E1 ENSG00000203857 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1 119507198-119515054 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043261, HPA043264, HPA044028 Supported Tissue enriched 12 placenta: 110.1 small intestine: 8.9 -HSD3B2 SDR11E2 ENSG00000203859 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 1 119414931-119423035 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043261, HPA043264, HPA044028 Supported Tissue enriched 436 adrenal gland: 2394.6 testis: 5.4 -RBM20 ENSG00000203867 RNA binding motif protein 20 10 110644397-110839469 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035806, HPA037703 Uncertain Approved Nucleus
Nucleoli
Golgi apparatus
Cytokinetic bridge Tissue enhanced 0 heart muscle: 26.5 skeletal muscle: 5.4 -SMIM9 CXorf68 ENSG00000203870 Small integral membrane protein 9 X 154823348-154834662 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA060970 Uncertain Tissue enriched 5 testis: 1.3 placenta: 0.2 -C6orf163 ENSG00000203872 Chromosome 6 open reading frame 163 6 87344849-87365463 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA044797, HPA052927 Uncertain Uncertain Nucleoplasm Tissue enriched 6 testis: 13.9 fallopian tube: 2.4 -RIPPLY2 C6orf159, dJ237I15.1 ENSG00000203877 Ripply transcriptional repressor 2 6 83853266-83857515 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047454 Uncertain Tissue enriched 8 cerebral cortex: 14.9 adrenal gland: 1.8 -GDI1 FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGDIA, XAP-4 ENSG00000203879 GDP dissociation inhibitor 1 X 154436913-154443467 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012979, HPA049290, HPA057668 Supported Approved Vesicles Tissue enriched 5 cerebral cortex: 533.6 smooth muscle: 99.9 -PCMTD2 C20orf36, FLJ10883 ENSG00000203880 Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 20 64255695-64287821 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA057849 Approved Approved Nucleoplasm
Mitochondria Expressed in all skin: 78.8 -SOX18 ENSG00000203883 SRY (sex determining region Y)-box 18 20 64047582-64049641 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA073703 Approved Nucleus Tissue enhanced 0 adipose tissue: 32.9 lung: 12.0 -LIME1 dJ583P15.4, FLJ20406, LIME ENSG00000203896 Lck interacting transmembrane adaptor 1 20 63736283-63739103 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015363 Approved Tissue enhanced 0 liver: 19.5;stomach: 17.9 kidney: 14.9 -OOEP C6orf156, Em:AC019205.2, KHDC2 ENSG00000203907 Oocyte expressed protein 6 73368555-73395133 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055165 Approved Tissue enriched 12 testis: 23.1 placenta: 1.9 -KHDC3L C6orf221, ECAT1 ENSG00000203908 KH domain containing 3-like, subcortical maternal complex member 6 73362677-73364171 Disease related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043699 Uncertain Tissue enhanced 0 lung: 1.0;testis: 2.2 epididymis: 0.4 -DPPA5 Esg1 ENSG00000203909 Developmental pluripotency associated 5 6 73353062-73354295 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA064505 Uncertain Tissue enhanced 0 testis: 3.8 lung: 0.9 -C1orf146 ENSG00000203910 Chromosome 1 open reading frame 146 1 92217940-92245813 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 14 testis: 14.5 skin: 1.0 -SPANXN1 CT11.6, SPANX-N1 ENSG00000203923 SPANX family, member N1 X 145246828-145256112 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 testis: 1.4 epididymis: 0.8 -SPANXA2 SPANX ENSG00000203926 SPANX family, member A2 X 141589435-141590772 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046423 Uncertain Supported Nucleoplasm
Vesicles Tissue enriched 43 testis: 4.3 epididymis: 0.0 -CXorf66 RP11-35F15.2, SGPX ENSG00000203933 Chromosome X open reading frame 66 X 139955725-139965520 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA048517 Approved Tissue enriched 76 testis: 24.1 liver: 0.3 -C10orf62 bA548K23.1 ENSG00000203942 Chromosome 10 open reading frame 62 10 97589727-97590934 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072947 Supported Tissue enriched 1082 testis: 243.5 kidney: 0.2 -SAMD13 ENSG00000203943 Sterile alpha motif domain containing 13 1 84298366-84389957 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA058929 Supported Approved Mitochondria Tissue enhanced 0 rectum: 26.5;testis: 28.8 colon: 21.2 -FAM127B CXX1b, DKFZP564B147, MAR8A ENSG00000203950 Family with sequence similarity 127, member B X 135050932-135052196 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all ovary: 24.6 -CCDC160 ENSG00000203952 Coiled-coil domain containing 160 X 134237047-134246207 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA044684 Uncertain Mixed parathyroid gland: 8.3 -C1orf141 ENSG00000203963 Chromosome 1 open reading frame 141 1 67092165-67231853 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035316 Approved Group enriched 13 fallopian tube: 15.4;testis: 28.1 lung: 1.6 -EFCAB7 KIAA1799, RP4-534K7.1 ENSG00000203965 EF-hand calcium binding domain 7 1 63523372-63572693 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029611, HPA029612, HPA029613 Supported Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Mixed testis: 24.5 -DEFB110 DEFB-10, DEFB-11, DEFB111 ENSG00000203970 Defensin, beta 110 6 50009138-50021981 Predicted secreted proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enriched 3638 epididymis: 1075.6 seminal vesicle: 0.2 -GLYATL3 bA28H17.2, C6orf140 ENSG00000203972 Glycine-N-acyltransferase-like 3 6 49499958-49527047 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044044 Uncertain Not detected liver: 0.7 -LDLRAD1 ENSG00000203985 Low density lipoprotein receptor class A domain containing 1 1 54007299-54018186 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052489 Approved Uncertain Nucleoplasm
Golgi apparatus Tissue enriched 21 fallopian tube: 253.3 lung: 11.8 -RHOXF2B ENSG00000203989 Rhox homeobox family, member 2B X 120070672-120077705 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA003314 Supported Tissue enriched 17 testis: 2.7 spleen: 0.1 -ZYG11A ZYG11 ENSG00000203995 Zyg-11 family member A, cell cycle regulator 1 52842511-52894998 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA030378, HPA030379 Uncertain Approved Nucleus Tissue enhanced 0 testis: 7.2;thyroid gland: 4.1 kidney: 3.1 -LCN8 LCN5 ENSG00000204001 Lipocalin 8 9 136754386-136758543 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 234 epididymis: 101.7 thyroid gland: 0.4 -C1orf185 FLJ27485 ENSG00000204006 Chromosome 1 open reading frame 185 1 51102234-51148086 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 241 testis: 42.7 parathyroid gland: 0.1 -GLT6D1 GLTDC1 ENSG00000204007 Glycosyltransferase 6 domain containing 1 9 135623656-135639540 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023424 Uncertain Tissue enriched 41 testis: 8.3 epididymis: 0.2 -IFIT1B bA149I23.6, IFIT1L ENSG00000204010 Interferon-induced protein with tetratricopeptide repeats 1B 10 89378056-89385205 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062924 Approved Group enriched 97 bone marrow: 15.3;placenta: 4.1 epididymis: 0.0 -CT83 CXorf61, FLJ20611, FLJ22913, KK-LC-1 ENSG00000204019 Cancer/testis antigen 83 X 116461682-116463003 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004773 Uncertain Tissue enriched 59 testis: 84.7 salivary gland: 1.4 -LIPN bA186O14.3, LIPL4 ENSG00000204020 Lipase, family member N 10 88761406-88778242 Disease related genes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 7 skin: 39.9 appendix: 5.8 -LIPK bA186O14.2, LIPL2 ENSG00000204021 Lipase, family member K 10 88724544-88752786 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 12 skin: 37.4 breast: 3.2 -LIPJ bA425M17.2, LIPL1 ENSG00000204022 Lipase, family member J 10 88586753-88606976 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048594 Uncertain Tissue enriched 11 testis: 12.2 epididymis: 1.1 -LRIT2 AC022389.4, LRRC22 ENSG00000204033 Leucine-rich repeat, immunoglobulin-like and transmembrane domains 2 10 84220495-84225589 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037788 Uncertain Tissue enhanced 0 cerebral cortex: 1.0;rectum: 1.2;skin: 3.1 colon: 0.6 -LRRC73 C6orf154, dJ337H4.2 ENSG00000204052 Leucine rich repeat containing 73 6 43506969-43510686 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046698 Approved Approved Cytosol Tissue enhanced 0 fallopian tube: 8.2;testis: 24.7 cerebral cortex: 6.6 -FOXO6 ENSG00000204060 Forkhead box O6 1 41361922-41383590 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 1.7 prostate: 0.7 -TCEAL5 WEX4 ENSG00000204065 Transcription elongation factor A (SII)-like 5 X 103273691-103276872 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045564, HPA058982, HPA072199 Uncertain Uncertain Nucleoplasm
Cytosol Group enriched 7 cerebral cortex: 82.7;testis: 82.5 adrenal gland: 11.9 -SYS1 C20orf169, dJ453C12.4 ENSG00000204070 Sys1 golgi trafficking protein 20 45361937-45376798 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046716 Approved Expressed in all fallopian tube: 51.3 -TCEAL6 WEX2 ENSG00000204071 Transcription elongation factor A (SII)-like 6 X 102140476-102142970 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045564, HPA058982 Uncertain Group enriched 6 adrenal gland: 15.0;cerebral cortex: 65.3;testis: 35.6 endometrium: 6.2 -INPP5B ENSG00000204084 Inositol polyphosphate-5-phosphatase B 1 37860697-37947057 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028803 Approved Approved Cytosol Expressed in all ovary: 26.2 -RPA4 HSU24186 ENSG00000204086 Replication protein A4, 30kDa X 96883908-96885467 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA066010 Approved Tissue enriched 8 testis: 2.1 placenta: 0.2 -NEU4 ENSG00000204099 Sialidase 4 2 241808825-241817413 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA037394, HPA037395 Uncertain Group enriched 7 bone marrow: 2.4;cerebral cortex: 6.4;colon: 8.5;duodenum: 5.7;liver: 4.1;rectum: 3.9;small intestine: 5.4 gallbladder: 0.8 -MAFB KRML ENSG00000204103 V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 20 40685848-40689240 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA005653 Approved Approved Nucleus
Nucleoli Tissue enriched 7 parathyroid gland: 677.4 spleen: 103.7 -TRAF3IP1 DKFZP434F124, IFT54, MIP-T3, MIPT3 ENSG00000204104 TNF receptor-associated factor 3 interacting protein 1 2 238320441-238400900 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037857, HPA037858 Approved Expressed in all fallopian tube: 30.9 -CHIC1 BRX ENSG00000204116 Cysteine-rich hydrophobic domain 1 X 73563200-73687102 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA026782, HPA052062 Uncertain Approved Nuclear speckles
Vesicles
Cytosol Mixed cerebral cortex: 14.2 -NAP1L6 FLJ33596 ENSG00000204118 Nucleosome assembly protein 1-like 6 X 73126037-73128080 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA044957 Uncertain Mixed thyroid gland: 1.2 -GIGYF2 GYF2, KIAA0642, PARK11, PERQ2, PERQ3, TNRC15 ENSG00000204120 GRB10 interacting GYF protein 2 2 232697299-232860575 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050899, HPA054612, HPA059918, HPA065064 Approved Validated Cytosol Expressed in all testis: 85.3 -C2orf72 LOC257407 ENSG00000204128 Chromosome 2 open reading frame 72 2 231037490-231049719 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044962 Uncertain Approved Nucleus
Plasma membrane Tissue enhanced 0 cerebral cortex: 2.8;colon: 3.0;liver: 4.7 stomach: 1.3 -RUFY2 FLJ10063, KIAA1537, RABIP4R, ZFYVE13 ENSG00000204130 RUN and FYVE domain containing 2 10 68341107-68407294 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039792 Approved Approved Nucleoplasm Expressed in all cerebral cortex: 36.9 -NHSL2 ENSG00000204131 NHS-like 2 X 71910818-72161750 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049771, HPA054858 Uncertain Approved Mitochondria Mixed smooth muscle: 8.8 -PHACTR4 FLJ13171, PPP1R124 ENSG00000204138 Phosphatase and actin regulator 4 1 28369582-28500369 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028985 Approved Approved Plasma membrane
Intermediate filaments
Cytosol Expressed in all esophagus: 35.9 -CLPSL1 C6orf127, dJ510O8.6 ENSG00000204140 Colipase-like 1 6 35781017-35793675 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA073155 Approved Tissue enriched 37 epididymis: 719.8 pancreas: 19.3 -ASAH2B ASAH2C, ASAH2L, bA449O16.3, bA98I6.3 ENSG00000204147 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B 10 50739318-50816495 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA061171 Supported Approved Focal adhesion sites Mixed duodenum: 20.1 -AGAP6 bA324H6.1, CTGLF3 ENSG00000204149 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 10 49982190-50010499 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042490 Uncertain Expressed in all skin: 21.9 -TIMM23B bA592B15.7 ENSG00000204152 Translocase of inner mitochondrial membrane 23 homolog B (yeast) 10 49942033-49974850 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Mixed bone marrow: 5.5 -ZDHHC18 DKFZp667O2416 ENSG00000204160 Zinc finger, DHHC-type containing 18 1 26826710-26857602 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040234 Approved Approved Microtubules Expressed in all bone marrow: 75.3 -C10orf128 Em:AC084727.5 ENSG00000204161 Chromosome 10 open reading frame 128 10 49154725-49188585 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA058166 Approved Mixed lung: 40.5 -CXorf65 ENSG00000204165 Chromosome X open reading frame 65 X 71103889-71106788 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA047396 Uncertain Tissue enriched 9 testis: 19.5 lymph node: 2.0 -AGAP9 bA301J7.2, CTGLF6, FLJ00312 ENSG00000204172 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 10 47501854-47523638 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA042490 Uncertain Expressed in all skin: 26.4 -NPY4R PP1, PPYR1, Y4 ENSG00000204174 Neuropeptide Y receptor Y4 10 46461099-46465881 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027863 Approved Tissue enhanced 0 colon: 9.0;rectum: 10.5 skin: 6.4 -GPRIN2 KIAA0514, MGC15171 ENSG00000204175 G protein regulated inducer of neurite outgrowth 2 10 46549044-46555530 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038129 Approved Approved Nucleoplasm Tissue enhanced 0 lung: 18.1;skin: 18.8 small intestine: 11.9 -SYT15 CHR10SYT ENSG00000204176 Synaptotagmin XV 10 46578217-46594173 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036971, HPA036972, HPA064559 Uncertain Approved Golgi apparatus Mixed lung: 21.5 -TMEM57 FLJ10747 ENSG00000204178 Transmembrane protein 57 1 25430858-25500209 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019680 Approved Cytosol Expressed in all testis: 36.0 -PTPN20 bA142I17.1, bA42B19.1, CT126, DKFZP566K0524, PTPN20A, PTPN20B ENSG00000204179 Protein tyrosine phosphatase, non-receptor type 20 10 46911396-47002488 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043337, HPA046896, HPA048310 Uncertain Supported Microtubule organizing center Tissue enhanced 0 testis: 25.0 adrenal gland: 12.2 -GDF5OS ENSG00000204183 Growth differentiation factor 5 opposite strand 20 35433029-35435450 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA062720 Uncertain Not detected adipose tissue: 0.3 -ZDBF2 FLJ45338, KIAA1571 ENSG00000204186 Zinc finger, DBF-type containing 2 2 206274663-206314428 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039121, HPA050311 Uncertain Validated Nucleoplasm
Cytosol Mixed cerebral cortex: 10.2 -TXNDC8 bA427L11.2, SPTRX-3, TRX6 ENSG00000204193 Thioredoxin domain containing 8 (spermatozoa) 9 110303521-110337884 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 59 testis: 43.8 fallopian tube: 0.7 -AWAT1 DGAT2L3 ENSG00000204195 Acyl-CoA wax alcohol acyltransferase 1 X 70234655-70240627 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA063412 Supported Not detected breast: 0.8 -DAXX DAP6 ENSG00000204209 Death-domain associated protein 6 33318558-33329269 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002224, HPA008736, HPA008797, CAB025546, HPA065779 Supported Validated Nucleus
Nuclear bodies Mixed epididymis: 19.0 -BMPR2 BMPR-II, BMPR3, BRK-3, PPH1, T-ALK ENSG00000204217 Bone morphogenetic protein receptor, type II (serine/threonine kinase) 2 202376936-202567751 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017385, HPA049014 Approved Approved Nucleoplasm
Plasma membrane Expressed in all cerebral cortex: 36.5 -TCEA3 TFIIS.H ENSG00000204219 Transcription elongation factor A (SII), 3 1 23381061-23424740 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044960, HPA055811 Approved Approved Nucleoplasm
Vesicles Tissue enhanced 0 skeletal muscle: 157.4 ovary: 62.6 -PFDN6 H2-KE2, HKE2, KE-2, PFD6 ENSG00000204220 Prefoldin subunit 6 6 33289302-33298401 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043032, HPA048123 Supported Approved Nucleus
Golgi apparatus Expressed in all testis: 20.9 -RING1 RNF1 ENSG00000204227 Ring finger protein 1 6 33208495-33212722 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008701 Supported Approved Nucleoplasm
Cytosol Mixed endometrium: 8.2 -HSD17B8 D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1 ENSG00000204228 Hydroxysteroid (17-beta) dehydrogenase 8 6 33204642-33206831 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042132 Supported Mixed parathyroid gland: 9.7 -RXRB H-2RIIBP, NR2B2, RCoR-1 ENSG00000204231 Retinoid X receptor, beta 6 33193588-33200688 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002003, HPA063653 Approved Supported Nucleus Mixed epididymis: 15.5 -OXLD1 C17orf90, MGC104712 ENSG00000204237 Oxidoreductase-like domain containing 1 17 81665036-81666635 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056878, HPA057019 Uncertain Approved Vesicles
Cytosol Mixed testis: 10.7 -OR13C3 ENSG00000204246 Olfactory receptor, family 13, subfamily C, member 3 9 104535749-104536856 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA053978 Uncertain Not detected testis: 0.7 -COL11A2 DFNA13, DFNB53, HKE5 ENSG00000204248 Collagen, type XI, alpha 2 6 33162681-33192499 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 testis: 1.2 cerebral cortex: 0.7 -HLA-DOA HLA-D0-alpha, HLA-DNA, HLA-DZA ENSG00000204252 Major histocompatibility complex, class II, DO alpha 6 33004178-33009612 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045038 Supported Tissue enhanced 0 spleen: 14.8 tonsil: 9.2 -BRD2 D6S113E, FSRG1, KIAA9001, NAT, RING3 ENSG00000204256 Bromodomain containing 2 6 32968660-32981505 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042816 Approved Validated Nuclear speckles Expressed in all thyroid gland: 101.5 -HLA-DMA D6S222E, RING6 ENSG00000204257 Major histocompatibility complex, class II, DM alpha 6 32948613-32969094 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012750, HPA017295 Supported Approved Vesicles Tissue enhanced 0 lung: 64.8 fallopian tube: 41.3 -COL5A2 ENSG00000204262 Collagen, type V, alpha 2 2 189031896-189179879 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed placenta: 152.7 -PSMB8 beta5i, D6S216E, LMP7, PSMB5i, RING10 ENSG00000204264 Proteasome subunit beta 8 6 32840717-32844703 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046995, HPA050327 Supported Approved Vesicles
Cytokinetic bridge Mixed lymph node: 23.3 -TAP2 ABCB3, D6S217E, PSF2, RING11 ENSG00000204267 Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6 32821833-32838780 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001312 Approved Approved Nuclear speckles
Endoplasmic reticulum Mixed urinary bladder: 15.7 -SPIN3 TDRD27 ENSG00000204271 Spindlin family, member 3 X 56976370-56995537 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000727 Uncertain Approved Nucleoplasm Mixed cerebral cortex: 11.2 -LINC01420 ENSG00000204272 Long intergenic non-protein coding RNA 1420 X 56729259-56818380 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Expressed in all thyroid gland: 50.8 -TMEM235 ENSG00000204278 Transmembrane protein 235 17 78231310-78240987 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053939 Uncertain Tissue enriched 101 cerebral cortex: 15.7 testis: 0.1 -PAGE3 CT16.6, GAGED1, PAGE-3 ENSG00000204279 P antigen family, member 3 (prostate associated) X 55258412-55264846 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062248 Uncertain Tissue enriched 85 testis: 8.5 epididymis: 0.0 -HLA-DRA HLA-DRA1 ENSG00000204287 Major histocompatibility complex, class II, DR alpha 6 32439842-32445046 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002798, CAB015402, HPA050162, HPA053176 Supported Tissue enhanced 0 lung: 729.2;lymph node: 906.6 tonsil: 492.4 -BTNL2 BTL-II, BTN7, HSBLMHC1 ENSG00000204290 Butyrophilin-like 2 6 32393963-32407128 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected prostate: 0.6 -COL15A1 ENSG00000204291 Collagen, type XV, alpha 1 9 98943179-99070792 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017913, HPA017915 Supported Approved Endoplasmic reticulum Tissue enhanced 0 placenta: 309.7 smooth muscle: 144.8 -OR8B2 ENSG00000204293 Olfactory receptor, family 8, subfamily B, member 2 11 124382395-124383362 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 26 testis: 2.5 adipose tissue: 0.0 -C6orf10 TSBP ENSG00000204296 Chromosome 6 open reading frame 10 6 32288526-32371912 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 72 testis: 15.7 ovary: 0.2 -TMEM225 PMP22CD, PPP1R154 ENSG00000204300 Transmembrane protein 225 11 123882926-123885642 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 395 testis: 39.4 epididymis: 0.0 -NOTCH4 INT3 ENSG00000204301 Notch 4 6 32194843-32224067 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lung: 12.1 thyroid gland: 4.2 -PBX2 G17, HOX12, PBX2MHC ENSG00000204304 Pre-B-cell leukemia homeobox 2 6 32184741-32190186 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061478 Supported Approved Nucleoplasm Expressed in all epididymis: 35.5 -AGER RAGE ENSG00000204305 Advanced glycosylation end product-specific receptor 6 32180968-32184324 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011682, HPA064436 Approved Approved Nucleoli fibrillar center
Plasma membrane
Cell Junctions Tissue enriched 181 lung: 891.2 thyroid gland: 4.9 -RNF5 G16, NG2, RING5, RMA1 ENSG00000204308 Ring finger protein 5, E3 ubiquitin protein ligase 6 32178354-32180793 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034107, HPA065032 Uncertain Supported Endoplasmic reticulum Mixed kidney: 18.5 -AGPAT1 LPAAT-alpha ENSG00000204310 1-acylglycerol-3-phosphate O-acyltransferase 1 6 32168212-32178096 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048478, HPA073355 Approved Supported Endoplasmic reticulum
Rods & Rings Mixed epididymis: 51.4 -DFNB59 pejvakin ENSG00000204311 Deafness, autosomal recessive 59 2 178451436-178461390 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042621 Supported Mitochondria Tissue enriched 6 testis: 32.2 ovary: 5.4 -PRRT1 C6orf31, IFITMD7, NG5 ENSG00000204314 Proline-rich transmembrane protein 1 6 32148359-32154373 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055149 Approved Tissue enriched 8 cerebral cortex: 4.5 ovary: 0.6 -FKBPL DIR1, NG7, WISp39 ENSG00000204315 FK506 binding protein like 6 32128707-32130291 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043478, HPA060158 Approved Approved Nucleoplasm Mixed thyroid gland: 5.0 -MRPL38 HSPC262, MGC4810, MRP-L3, RPML3 ENSG00000204316 Mitochondrial ribosomal protein L38 17 75898643-75905413 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023054, HPA023135 Approved Supported Mitochondria Expressed in all fallopian tube: 30.2 -SMIM5 C17orf109 ENSG00000204323 Small integral membrane protein 5 17 75633434-75641404 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA065332, HPA071268 Approved Approved Golgi apparatus
Vesicles Mixed thyroid gland: 14.7 -ERICH2 ENSG00000204334 Glutamate-rich 2 2 170783786-170798971 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA061010 Approved Nucleoli fibrillar center
Vesicles Tissue enriched 8 testis: 232.3 thyroid gland: 30.5 -SP5 ENSG00000204335 Sp5 transcription factor 2 170715351-170718078 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA074123 Approved Nucleus
Nucleoli Tissue enhanced 0 endometrium: 3.9 stomach: 2.4 -STK19 D6S60, G11, RP1 ENSG00000204344 Serine/threonine kinase 19 6 31971091-31982821 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031510, HPA031511, HPA068559 Uncertain Supported Nuclear speckles Mixed testis: 1.0 -CD300LD CD300D, CMRF35A4 ENSG00000204345 CD300 molecule-like family member d 17 74579365-74592283 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA027756 Uncertain Mixed breast: 1.0 -BTBD17 BTBD17A, LGALS3BPL, TANGO10A ENSG00000204347 BTB (POZ) domain containing 17 17 74356416-74361946 Predicted secreted proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA025022 Approved Tissue enriched 19 cerebral cortex: 12.9 adrenal gland: 0.6 -DXO DOM3Z ENSG00000204348 Decapping exoribonuclease 6 31969810-31972292 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046708 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Mixed testis: 5.7 -SKIV2L 170A, DDX13, HLP, SKI2W, SKIV2 ENSG00000204351 SKI2 homolog, superkiller viralicidic activity 2-like 6 31959080-31969755 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051959, HPA054419 Uncertain Approved Nucleoplasm Mixed epididymis: 10.3 -C9orf129 bA165J3.3 ENSG00000204352 Chromosome 9 open reading frame 129 9 93318199-93346414 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA071515 Uncertain Mitochondria Group enriched 7 cerebral cortex: 4.1;testis: 1.7 epididymis: 0.4 -NELFE D6S45, NELF-E, RD, RDBP, RDP ENSG00000204356 Negative elongation factor complex member E 6 31952087-31959110 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007187, HPA007594, HPA046502 Approved Validated Nucleoplasm
Nuclear bodies Expressed in all testis: 49.6 -NXPE2 FAM55B, FLJ25224 ENSG00000204361 Neurexophilin and PC-esterase domain family, member 2 11 114678386-114706933 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA039744, HPA039876 Supported Tissue enhanced 0 colon: 9.7;epididymis: 29.8;rectum: 9.9 salivary gland: 8.2 -SPANXN5 CT11.10, SPANX-N5 ENSG00000204363 SPANX family, member N5 X 52796144-52798101 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 106 testis: 11.4 placenta: 0.1 -ZBTB12 C6orf46, D6S59E, G10, NG35 ENSG00000204366 Zinc finger and BTB domain containing 12 6 31899607-31901992 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047161 Approved Mixed endometrium: 1.8 -SDHD PGL, PGL1 ENSG00000204370 Succinate dehydrogenase complex, subunit D, integral membrane protein 11 112086773-112120013 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045727 Approved Expressed in all kidney: 303.5 -EHMT2 BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a ENSG00000204371 Euchromatic histone-lysine N-methyltransferase 2 6 31879759-31897687 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050550, HPA060259 Supported Supported Nucleoplasm
Nuclear speckles Mixed cerebral cortex: 4.7 -XAGE1A CT12.1a, GAGED2, XAGE-1, XAGE1 ENSG00000204379 X antigen family, member 1A X 52495676-52500812 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA077164 Uncertain Nuclear speckles Tissue enriched 186 testis: 65.5 cervix: 0.3 -LAYN FLJ30977, FLJ31092 ENSG00000204381 Layilin 11 111540280-111561745 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA040087 Approved Approved Cytosol Mixed ovary: 49.5 -XAGE1B CT12.1b ENSG00000204382 X antigen family, member 1B X 52512077-52520803 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA077164 Uncertain Nuclear speckles Tissue enriched 41 testis: 70.0 lung: 1.6 -SLC44A4 C6orf29, CTL4, FLJ14491, NG22, TPPT ENSG00000204385 Solute carrier family 44, member 4 6 31863192-31879046 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046977, HPA054176 Approved Tissue enhanced 0 duodenum: 36.0 prostate: 30.1 -NEU1 NEU ENSG00000204386 Sialidase 1 (lysosomal sialidase) 6 31857659-31862906 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015634, HPA021506 Approved Supported Vesicles
Cell Junctions Mixed thyroid gland: 14.3 -C6orf48 D6S57, G8 ENSG00000204387 Chromosome 6 open reading frame 48 6 31834608-31839766 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Expressed in all ovary: 110.5 -HSPA1B HSP70-2 ENSG00000204388 Heat shock 70kDa protein 1B 6 31827735-31830255 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level CAB008640, HPA052504 Approved Uncertain Nucleoplasm
Vesicles Tissue enhanced 0 adrenal gland: 34.3 urinary bladder: 15.0 -HSPA1A HSP70-1, HSPA1 ENSG00000204389 Heat shock 70kDa protein 1A 6 31815464-31817946 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level CAB017451, CAB032815, HPA052504 Supported Uncertain Nucleoplasm
Vesicles Mixed adrenal gland: 49.9 -HSPA1L HSP70-HOM, hum70t ENSG00000204390 Heat shock 70kDa protein 1-like 6 31809619-31815065 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043285, HPA052504 Supported Uncertain Nucleoplasm
Vesicles Tissue enriched 8 testis: 9.7 epididymis: 1.1 -LSM2 C6orf28, G7b, YBL026W ENSG00000204392 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated 6 31797396-31806984 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066718 Supported Supported Nucleus Mixed fallopian tube: 7.1 -VARS VARS2 ENSG00000204394 Valyl-tRNA synthetase 6 31777518-31795953 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046710 Approved Validated Cytosol Mixed testis: 5.5 -VWA7 C6orf27, G7c, NG37 ENSG00000204396 Von Willebrand factor A domain containing 7 6 31765590-31777294 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046954, HPA054262, HPA055033 Approved Approved Plasma membrane
Cytosol Tissue enhanced 0 fallopian tube: 9.0 parathyroid gland: 1.9 -CARD16 COP, COP1, PSEUDO-ICE ENSG00000204397 Caspase recruitment domain family, member 16 11 105041326-105101431 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053981, HPA062805 Uncertain Approved Mitochondria Expressed in all spleen: 161.8 -MBD5 FLJ11113, KIAA1461 ENSG00000204406 Methyl-CpG binding domain protein 5 2 148021011-148516971 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035964 Supported Nucleus
Midbody Mixed parathyroid gland: 12.0 -MSH5 ENSG00000204410 MutS homolog 5 6 31739948-31762834 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062688 Approved Endoplasmic reticulum
Vesicles Mixed skin: 1.8 -CSHL1 CS-5, CSHP1, CSL, hCS-L, MGC149868 ENSG00000204414 Chorionic somatomammotropin hormone-like 1 17 63909597-63918838 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB025646, HPA043715 Supported Tissue enriched 356 placenta: 216.4 smooth muscle: 0.6 -C6orf25 G6b, NG31 ENSG00000204420 Chromosome 6 open reading frame 25 6 31718594-31726714 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA073017 Uncertain Golgi apparatus Not detected skin: 0.8 -LY6G6C C6orf24, G6c, NG24 ENSG00000204421 Lymphocyte antigen 6 complex, locus G6C 6 31718648-31721845 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 8 skin: 64.4 esophagus: 7.6 -XXbac-BPG32J3.20 ENSG00000204422 6 31686962-31714072 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Not detected thyroid gland: 0.9 -LY6G6F C6orf21, G6f, LY6G6D, NG32 ENSG00000204424 Lymphocyte antigen 6 complex, locus G6F 6 31706885-31710595 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008053 Uncertain Not detected bone marrow: 0.5 -ABHD16A BAT5, D6S82E, NG26 ENSG00000204427 Abhydrolase domain containing 16A 6 31686949-31703444 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058606 Approved Tissue enhanced 0 gallbladder: 1.7;testis: 1.3;thyroid gland: 1.3 esophagus: 0.9 -LY6G5C C6orf20, G5c, NG33 ENSG00000204428 Lymphocyte antigen 6 complex, locus G5C 6 31676684-31684040 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038690 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 1.5 testis: 1.0 -CSNK2B ENSG00000204435 Casein kinase 2, beta polypeptide 6 31665236-31670343 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004349, HPA005944, CAB013087, CAB016059 Approved Mixed epididymis: 54.3 -GPANK1 ANKRD59, BAT4, D6S54E, G5, GPATCH10 ENSG00000204438 G patch domain and ankyrin repeats 1 6 31661229-31666283 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006301 Approved Approved Endoplasmic reticulum Mixed testis: 9.8 -C6orf47 D6S53E, G4 ENSG00000204439 Chromosome 6 open reading frame 47 6 31658298-31660772 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045281, HPA053373 Uncertain Approved Cytosol Mixed skin: 5.4 -FAM155A ENSG00000204442 Family with sequence similarity 155, member A 13 107163510-107866735 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039453, HPA058768 Supported Approved Nucleus
Vesicles
Centrosome Tissue enriched 6 cerebral cortex: 15.6 seminal vesicle: 2.4 -APOM ApoM, G3a, NG20 ENSG00000204444 Apolipoprotein M 6 31652416-31658210 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034086, HPA051006 Approved Approved Golgi apparatus Mixed testis: 5.6 -TRIM49C TRIM49L2 ENSG00000204449 Tripartite motif containing 49C 11 90031106-90042025 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.2 -TRIM64 C11orf28, TRIM64A ENSG00000204450 Tripartite motif containing 64 11 89968502-89975228 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045370 Approved Tissue enriched 11 placenta: 1.1 adipose tissue: 0.0 -BAG6 BAT3, D6S52E, G3 ENSG00000204463 BCL2-associated athanogene 6 6 31639028-31652705 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020704, HPA045116, HPA053291 Supported Validated Nucleoplasm
Cytosol Expressed in all testis: 135.8 -PRRC2A BAT2, D6S51E, G2 ENSG00000204469 Proline-rich coiled-coil 2A 6 31620720-31637771 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB026383, HPA046791 Uncertain Mixed testis: 20.8 -AIF1 AIF-1, Em:AF129756.17, IBA1, IRT-1 ENSG00000204472 Allograft inflammatory factor 1 6 31615184-31617021 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049234 Supported Tissue enhanced 0 spleen: 79.6 appendix: 51.6 -NCR3 1C7, CD337, LY117, NKp30 ENSG00000204475 Natural cytotoxicity triggering receptor 3 6 31588895-31592985 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 1.8;spleen: 1.6;tonsil: 1.2 appendix: 1.1 -PRAMEF20 OTTHUMT00000008157, PRAMEF21 ENSG00000204478 PRAME family member 20 1 13410450-13421328 Predicted intracellular proteins No evidence No evidence No evidence Not detected testis: 0.2 -PRAMEF17 ENSG00000204479 PRAME family member 17 1 13389632-13392629 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -PRAMEF19 ENSG00000204480 PRAME family member 19 1 13369067-13371693 Predicted intracellular proteins No evidence No evidence No evidence HPA057423 Uncertain Not detected adipose tissue: 0.0 -PRAMEF14 ENSG00000204481 PRAME family member 14 1 13342034-13347134 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -LST1 B144, D6S49E, LST-1 ENSG00000204482 Leukocyte specific transcript 1 6 31586124-31588909 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 68.8;spleen: 49.9 appendix: 33.1 -NFKBIL1 IKBL, NFKBIL ENSG00000204498 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 6 31546870-31558829 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed fallopian tube: 4.1 -PRAMEF15 ENSG00000204501 PRAME family member 15 1 13303509-13322598 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -PRAMEF9 ENSG00000204505 PRAME family member 9 1 13172455-13179464 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -PRAMEF7 ENSG00000204510 PRAME family member 7 1 12916610-12920482 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA049887, HPA051704 Uncertain Not detected epididymis: 0.0 -MCCD1 ENSG00000204511 Mitochondrial coiled-coil domain 1 6 31528717-31530232 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046948 Uncertain Tissue enriched 36 kidney: 3.5 epididymis: 0.0 -ZNF814 ENSG00000204514 Zinc finger protein 814 19 57848731-57889074 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA043800, HPA053762, HPA072145 Approved Uncertain Nucleus Mixed thyroid gland: 18.5 -MICB PERB11.2 ENSG00000204516 MHC class I polypeptide-related sequence B 6 31494881-31511124 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064618 Approved Golgi apparatus
Vesicles Tissue enhanced 0 lymph node: 3.3 spleen: 2.8 -AADACL4 ENSG00000204518 Arylacetamide deacetylase-like 4 1 12644547-12667086 Predicted membrane proteins Evidence at protein level No evidence No evidence Evidence at protein level HPA043588 Uncertain Not detected epididymis: 0.7 -ZNF551 DKFZp686H1038 ENSG00000204519 Zinc finger protein 551 19 57681969-57717301 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038187, HPA038188 Uncertain Approved Nucleoplasm
Nuclear speckles Mixed testis: 8.1 -MICA PERB11.1 ENSG00000204520 MHC class I polypeptide-related sequence A 6 31399784-31415315 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed lung: 11.8 -ZNF805 ENSG00000204524 Zinc finger protein 805 19 57240685-57255135 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057665, HPA058895 Uncertain Mixed parathyroid gland: 5.0 -HLA-C D6S204, HLA-JY3, PSORS1 ENSG00000204525 Major histocompatibility complex, class I, C 6 31268749-31272130 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lung: 748.5 small intestine: 405.4 -POU5F1 MGC22487, OCT3, Oct4, OTF3 ENSG00000204531 POU class 5 homeobox 1 6 31164337-31180731 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025600, CAB026380, HPA058267 Approved Supported Nucleoplasm
Cytosol Mixed small intestine: 5.8 -ZSCAN5CP ZNF495C, ZSCAN5C ENSG00000204532 Zinc finger and SCAN domain containing 5C, pseudogene 19 56202301-56209452 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level No evidence HPA041263, HPA043123, HPA046836, HPA060667 Uncertain Uncertain Nuclear speckles Not detected testis: 0.1 -CCHCR1 C6orf18, HCR ENSG00000204536 Coiled-coil alpha-helical rod protein 1 6 31142439-31158238 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054167 Supported Cytosol Tissue enriched 6 testis: 86.7 fallopian tube: 13.6 -PSORS1C2 C6orf17, SPR1 ENSG00000204538 Psoriasis susceptibility 1 candidate 2 6 31137536-31139350 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA061228 Supported Tissue enriched 57 skin: 24.0 testis: 0.4 -CDSN D6S586E ENSG00000204539 Corneodesmosin 6 31115090-31120446 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044730, HPA054184 Supported Tissue enriched 43 skin: 77.2 epididymis: 1.7 -PSORS1C1 C6orf16, SEEK1 ENSG00000204540 Psoriasis susceptibility 1 candidate 1 6 31114750-31140092 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045049 Uncertain Nucleus Tissue enriched 10 testis: 33.5 epididymis: 3.2 -C6orf15 STG ENSG00000204542 Chromosome 6 open reading frame 15 6 31111223-31112559 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA001436 Uncertain Tissue enhanced 0 cervix, uterine: 1.9 tonsil: 0.8 -MUC21 bCX31G15.2, C6orf205 ENSG00000204544 Mucin 21, cell surface associated 6 30983718-30989903 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052028 Supported Tissue enriched 47 esophagus: 598.5 tonsil: 12.7 -DEFB121 DEFB-21 ENSG00000204548 Defensin, beta 121 20 31404845-31412838 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 6416 epididymis: 1966.4 testis: 0.3 -DHX16 DBP2, DDX16, Prp2, PRPF2 ENSG00000204560 DEAH (Asp-Glu-Ala-His) box polypeptide 16 6 30653119-30673037 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051455 Supported Supported Nucleoplasm Mixed testis: 11.5 -C6orf136 Em:AB023049.8 ENSG00000204564 Chromosome 6 open reading frame 136 6 30647039-30653210 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046804 Uncertain Mixed parathyroid gland: 8.0 -MRPS18B C6orf14, HSPC183, MRPS18-2, PTD017 ENSG00000204568 Mitochondrial ribosomal protein S18B 6 30617709-30626395 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043485, HPA050334 Supported Supported Cell Junctions
Mitochondria Expressed in all parathyroid gland: 13.2 -PPP1R10 CAT53, FB19, p99, PNUTS ENSG00000204569 Protein phosphatase 1, regulatory subunit 10 6 30600400-30618612 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025501, HPA047248, HPA056756 Supported Validated Nucleoplasm
Nuclear bodies Mixed parathyroid gland: 10.3 -KRTAP5-11 KRTAP5-6, KRTAP5.11 ENSG00000204571 Keratin associated protein 5-11 11 71579714-71603353 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected duodenum: 0.1 -KRTAP5-10 KRTAP5.10 ENSG00000204572 Keratin associated protein 5-10 11 71565563-71568934 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 1.9 seminal vesicle: 0.4 -ABCF1 ABC50, EST123147 ENSG00000204574 ATP-binding cassette, sub-family F (GCN20), member 1 6 30571376-30597179 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017578 Approved Validated Cytosol Mixed parathyroid gland: 11.1 -PRR3 CAT56, Em:AB014077.1, Em:AB023052.2 ENSG00000204576 Proline rich 3 6 30556886-30563723 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064061 Approved Nucleoplasm
Cytosol Mixed epididymis: 1.5 -LILRB3 CD85a, HL9, ILT5, LIR-3, LIR3 ENSG00000204577 Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 19 54216278-54223506 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 6 adipose tissue: 5.3;appendix: 10.4;bone marrow: 8.3;lung: 8.7;spleen: 9.4;urinary bladder: 6.9 placenta: 1.3 -DDR1 CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6 ENSG00000204580 Discoidin domain receptor tyrosine kinase 1 6 30876421-30900156 CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB010162, CAB025656, HPA057194 Approved Approved Nucleoplasm
Cell Junctions Mixed cerebral cortex: 51.7 -LRCOL1 ENSG00000204583 Leucine rich colipase-like 1 12 132603150-132610543 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 61 epididymis: 53.7 lung: 0.8 -GNL1 HSR1 ENSG00000204590 Guanine nucleotide binding protein-like 1 6 30541377-30557174 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033575, HPA043338, HPA050455 Uncertain Supported Vesicles Mixed parathyroid gland: 18.4 -HLA-E ENSG00000204592 Major histocompatibility complex, class I, E 6 30489467-30494205 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB024589, HPA031454 Supported Approved Vesicles Mixed skin: 153.8 -DPRX ENSG00000204595 Divergent-paired related homeobox 19 53632056-53637009 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA043682 Uncertain Tissue enhanced 0 placenta: 1.9 epididymis: 0.5 -TRIM39 RNF23 ENSG00000204599 Tripartite motif containing 39 6 30326479-30343729 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051120, HPA059496 Uncertain Supported Cytosol Mixed testis: 4.1 -ZNF468 ENSG00000204604 Zinc finger protein 468 19 52838008-52857649 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all thyroid gland: 20.3 -TRIM15 RNF93, ZNF178, ZNFB7 ENSG00000204610 Tripartite motif containing 15 6 30163206-30172696 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047527 Uncertain Tissue enhanced 0 colon: 2.7;duodenum: 3.7 small intestine: 1.1 -ZNF616 MGC45556 ENSG00000204611 Zinc finger protein 616 19 52113091-52139922 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA062639, HPA071539 Approved Approved Centrosome Expressed in all adrenal gland: 17.4 -FOXB2 bA159H20.4 ENSG00000204612 Forkhead box B2 9 77019655-77020953 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA067947 Uncertain Not detected epididymis: 0.0 -TRIM10 HERF1, RFB30, RNF9 ENSG00000204613 Tripartite motif containing 10 6 30151945-30160934 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level HPA043325 Uncertain Not detected kidney: 0.4 -TRIM40 RNF35 ENSG00000204614 Tripartite motif containing 40 6 30136108-30148735 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043818 Uncertain Not detected colon: 0.4 -TRIM31 C6orf13, HCG1, HCGI, RNF ENSG00000204616 Tripartite motif containing 31 6 30102897-30113106 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046400 Uncertain Group enriched 6 colon: 10.1;small intestine: 2.3;stomach: 2.1;urinary bladder: 2.8 duodenum: 0.7 -RNF39 HZFw1, LIRF ENSG00000204618 Ring finger protein 39 6 30070266-30075887 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level CAB019278, HPA047115 Uncertain Uncertain Vesicles
Plasma membrane
Centrosome Tissue enhanced 0 skin: 3.5 breast: 2.1 -PPP1R11 CFAP255, HCG-V, HCGV, TCTE5, Tctex5 ENSG00000204619 Protein phosphatase 1, regulatory (inhibitor) subunit 11 6 30066709-30070333 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043266, HPA060174 Approved Approved Nucleus
Vesicles Tissue enhanced 0 epididymis: 37.3 fallopian tube: 16.9 -PTCHD2 DISP3, KIAA1337 ENSG00000204624 Patched domain containing 2 1 11479166-11537584 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA054579 Uncertain Uncertain Nucleoplasm
Cytosol Group enriched 14 cerebral cortex: 8.7;testis: 4.3 adrenal gland: 0.4 -GNB2L1 Gnb2-rs1, H12.3, RACK1 ENSG00000204628 Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 5 181236909-181248096 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004288, HPA021676 Uncertain Validated Nucleoplasm
Cytosol Expressed in all ovary: 2104.6 -HLA-G ENSG00000204632 Major histocompatibility complex, class I, G 6 29826967-29831125 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016158 Supported Tissue enriched 23 placenta: 14.8 testis: 0.6 -TBC1D8 AD3, HBLP1, VRP ENSG00000204634 TBC1 domain family, member 8 (with GRAM domain) 2 101007617-101252866 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB015211, HPA037496 Uncertain Supported Nucleus Expressed in all seminal vesicle: 44.7 -NMS ENSG00000204640 Neuromedin S 2 100470482-100483280 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035420 Uncertain Tissue enriched 13 testis: 1.2 adipose tissue: 0.0 -HLA-F ENSG00000204642 Major histocompatibility complex, class I, F 6 29722775-29738528 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 40.6 duodenum: 28.3 -ZFP57 bA145L22, bA145L22.2, C6orf40, ZNF698 ENSG00000204644 ZFP57 zinc finger protein 6 29672392-29681110 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA047172 Uncertain Not detected heart muscle: 0.4 -ASPDH ENSG00000204653 Aspartate dehydrogenase domain containing 19 50511600-50514690 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042631, HPA042654 Approved Group enriched 7 cerebral cortex: 17.9;duodenum: 7.1;kidney: 27.9;liver: 34.6 adrenal gland: 3.3 -MOG BTN6, BTNL11 ENSG00000204655 Myelin oligodendrocyte glycoprotein 6 29656981-29672372 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021873 Supported Not detected cerebral cortex: 0.9 -OR2H2 hs6M1-12 ENSG00000204657 Olfactory receptor, family 2, subfamily H, member 2 6 29587455-29589038 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -CBY3 ENSG00000204659 Chibby homolog 3 (Drosophila) 5 179678583-179680974 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA069037 Uncertain Tissue enriched 6 testis: 4.7 spleen: 0.8 -C9orf57 ENSG00000204669 Chromosome 9 open reading frame 57 9 72051376-72072721 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 228 testis: 25.9 parathyroid gland: 0.1 -IL31 IL-31 ENSG00000204671 Interleukin 31 12 122172030-122174199 Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level CAB025657 Approved Not detected testis: 0.3 -AKT1S1 Lobe, MGC2865, PRAS40 ENSG00000204673 AKT1 substrate 1 (proline-rich) 19 49869033-49878459 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021903, HPA043590, HPA064427 Uncertain Supported Cytosol Expressed in all skeletal muscle: 33.9 -FAM153C NY-REN-7-like ENSG00000204677 Family with sequence similarity 153, member C 5 178006405-178055559 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042585, HPA046691, HPA052337 Uncertain Tissue enriched 5 testis: 41.7 cerebral cortex: 8.1 -GABBR1 GPRC3A, hGB1a ENSG00000204681 Gamma-aminobutyric acid (GABA) B receptor, 1 6 29555629-29633976 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050483, HPA058459 Uncertain Uncertain Centrosome Tissue enhanced 0 cerebral cortex: 20.9 spleen: 13.3 -CASC10 bA418C1.3, C10orf114 ENSG00000204682 Cancer susceptibility candidate 10 10 21492658-21497262 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA064131 Uncertain Approved Nucleoplasm Mixed placenta: 4.0 -C10orf113 bA165O3.1 ENSG00000204683 Chromosome 10 open reading frame 113 10 21125763-21146559 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA037013 Uncertain Tissue enriched 13 testis: 1.8 gallbladder: 0.1 -MAS1L dJ994E9.2, MAS-L, MRG ENSG00000204687 MAS1 proto-oncogene like, G protein-coupled receptor 6 29486697-29487956 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA017983 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 cervix, uterine: 5.1 epididymis: 2.3 -OR2H1 OR2H6, OR2H8, OR6-2 ENSG00000204688 Olfactory receptor, family 2, subfamily H, member 1 6 29457181-29464328 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.9 -OR11A1 hs6M1-18, OR11A2 ENSG00000204694 Olfactory receptor, family 11, subfamily A, member 1 6 29425504-29457071 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -OR14J1 hs6M1-28, OR5U1 ENSG00000204695 Olfactory receptor, family 14, subfamily J, member 1 6 29306690-29307655 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA045575 Uncertain Not detected testis: 0.1 -OR2J2 dJ80I19.4, hs6M1-6, OR6-8 ENSG00000204700 Olfactory receptor, family 2, subfamily J, member 2 6 29173303-29174574 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -OR2J3 OR6-6 ENSG00000204701 Olfactory receptor, family 2, subfamily J, member 3 6 29111891-29112826 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -OR2B3 OR2B3P, OR6-4 ENSG00000204703 Olfactory receptor, family 2, subfamily B, member 3 6 29086307-29087313 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -OR2W1 hs6M1-15 ENSG00000204704 Olfactory receptor, family 2, subfamily W, member 1 6 29044213-29045240 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -SPDYC Ringo2 ENSG00000204710 Speedy/RINGO cell cycle regulator family member C 11 65170154-65173244 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039891 Uncertain Tissue enhanced 0 liver: 1.4;testis: 1.5 epididymis: 0.4 -C9orf135 ENSG00000204711 Chromosome 9 open reading frame 135 9 69820793-69906232 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA021261, HPA021325 Uncertain Group enriched 8 fallopian tube: 54.5;testis: 24.2 parathyroid gland: 5.0 -TRIM27 RFP, RNF76 ENSG00000204713 Tripartite motif containing 27 6 28903002-28923989 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048684, HPA053408 Supported Approved Nucleus
Nucleoli Mixed appendix: 5.8 -MALRD1 bA265G8.2, C10orf112, Diet1 ENSG00000204740 MAM and LDL receptor class A domain containing 1 10 19048771-19790401 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA035732, HPA038106, HPA046848 Uncertain Validated Golgi apparatus Group enriched 8 duodenum: 32.2;small intestine: 35.1 testis: 4.4 -RANBP17 ENSG00000204764 RAN binding protein 17 5 170861870-171300015 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029568, HPA029569 Uncertain Approved Nuclear membrane
Nuclear bodies
Cytosol Tissue enhanced 0 testis: 5.0 thyroid gland: 1.7 -FAM196B C5orf57 ENSG00000204767 Family with sequence similarity 196, member B 5 169864264-169980740 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047227 Uncertain Tissue enhanced 0 breast: 7.6;cerebral cortex: 7.0 ovary: 2.1 -FOXD4L5 bA15J10.2 ENSG00000204779 Forkhead box D4-like 5 9 65282101-65285209 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA012836 Uncertain Approved Nucleus Tissue enhanced 0 epididymis: 1.2 cerebral cortex: 0.6 -TTC25 DKFZP434H0115 ENSG00000204815 Tetratricopeptide repeat domain 25 17 41930635-41965651 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023908 Supported Group enriched 8 fallopian tube: 46.9;testis: 70.3 parathyroid gland: 7.2 -MRPL53 ENSG00000204822 Mitochondrial ribosomal protein L53 2 74471958-74473322 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056185 Uncertain Expressed in all lymph node: 25.0 -MROH6 C8orf73 ENSG00000204839 Maestro heat-like repeat family member 6 8 143566187-143572971 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA068049 Uncertain Approved Nucleus Mixed bone marrow: 4.0 -ATXN2 ATX2, SCA2, TNRC13 ENSG00000204842 Ataxin 2 12 111452214-111599676 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018295, HPA020339, HPA021146 Supported Validated Cytosol Expressed in all testis: 41.1 -DCTN1 ENSG00000204843 Dynactin 1 2 74361154-74392087 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009108, HPA034635 Approved Supported Actin filaments
Centrosome
Cytosol Expressed in all cerebral cortex: 210.5 -SPATA31A1 C9orf36, C9orf36A, DKFZP434B204, FAM75A1, FAM75A2, SPATA31A2 ENSG00000204849 SPATA31 subfamily A, member 1 9 39355669-39361959 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enriched 80 testis: 8.0 adipose tissue: 0.0 -PNMAL2 KIAA1183 ENSG00000204851 Paraneoplastic Ma antigen family-like 2 19 46486906-46496498 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054810 Approved Group enriched 5 adrenal gland: 12.2;cerebral cortex: 33.0 ovary: 4.3 -TCTN1 FLJ21127, JBTS13, TECT1 ENSG00000204852 Tectonic family member 1 12 110614027-110649430 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039687, HPA040036 Approved Approved Nucleoplasm
Actin filaments Mixed fallopian tube: 43.7 -FAM216A C12orf24, HSU79274 ENSG00000204856 Family with sequence similarity 216, member A 12 110468364-110490385 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA038286 Approved Approved Actin filaments Group enriched 7 cerebral cortex: 16.2;testis: 60.9 appendix: 5.7 -ZBTB48 HKR3, ZNF855 ENSG00000204859 Zinc finger and BTB domain containing 48 1 6580001-6589280 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030417 Uncertain Approved Nucleoplasm
Cytosol Expressed in all testis: 32.9 -IGFL2 UNQ645 ENSG00000204866 IGF-like family member 2 19 46143106-46161299 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059137 Uncertain Approved Nucleoplasm
Plasma membrane Tissue enriched 6 skin: 35.5 parathyroid gland: 5.7 -IGFL4 ENSG00000204869 IGF-like family member 4 19 46039748-46077118 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047655 Approved Approved Cytosol Tissue enhanced 0 skin: 8.1 parathyroid gland: 3.2 -KRTAP9-3 KAP9.3 ENSG00000204873 Keratin associated protein 9-3 17 41232463-41233454 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -KRTAP4-8 KAP4.8 ENSG00000204880 Keratin associated protein 4-8 17 41096981-41098141 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -GPR20 ENSG00000204882 G protein-coupled receptor 20 8 141356500-141367267 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed smooth muscle: 1.2 -KRTAP1-4 KAP1.4 ENSG00000204887 Keratin associated protein 1-4 17 41029697-41030104 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected skin: 0.1 -KRT40 FLJ36600, KA36 ENSG00000204889 Keratin 40, type I 17 40977716-40987135 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected lung: 0.2 -KRT25 KRT25A ENSG00000204897 Keratin 25, type I 17 40748021-40755332 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053977, HPA058943 Supported Group enriched 15 breast: 3.6;testis: 1.6 smooth muscle: 0.1 -MZT1 C13orf37, FLJ21869, LOC440145, MGC150539, MOZART1, RP11-11C5.2 ENSG00000204899 Mitotic spindle organizing protein 1 13 72708357-72727687 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063299, HPA066715 Approved Expressed in all cerebral cortex: 30.2 -SPINK9 ENSG00000204909 Serine peptidase inhibitor, Kazal type 9 5 148321203-148339849 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038288 Uncertain Mixed testis: 5.4 -LRRC3C ENSG00000204913 Leucine rich repeat containing 3C 17 39941474-39944747 Predicted membrane proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level HPA071271 Uncertain Not detected testis: 0.9 -PRR20B ENSG00000204918 Proline rich 20B 13 57147488-57150509 Predicted intracellular proteins No evidence No evidence No evidence HPA059485 Uncertain Not detected testis: 0.1 -PRR20A FLJ40296, PRR20 ENSG00000204919 Proline rich 20A 13 57140918-57143939 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA059485 Uncertain Not detected testis: 0.1 -ZNF155 pHZ-96 ENSG00000204920 Zinc finger protein 155 19 43967862-43998325 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA003220 Uncertain Approved Nucleoplasm
Cytosol Mixed parathyroid gland: 14.6 -UQCC3 C11orf83, UNQ655 ENSG00000204922 Ubiquinol-cytochrome c reductase complex assembly factor 3 11 62670273-62673687 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046851 Approved Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all small intestine: 8.2 -FBXO48 ENSG00000204923 F-box protein 48 2 68459419-68467258 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049775, HPA054782 Uncertain Approved Nuclear bodies Mixed skin: 3.0 -GRXCR2 DFNB101 ENSG00000204928 Glutaredoxin, cysteine rich 2 5 145859733-145872968 Disease related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA059421 Uncertain Tissue enhanced 0 testis: 1.5 heart muscle: 0.4 -FAM221B C9orf128 ENSG00000204930 Family with sequence similarity 221, member B 9 35816391-35828747 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023011, HPA026577 Uncertain Group enriched 6 bone marrow: 2.4;testis: 10.4 prostate: 1.1 -CD177 HNA2A, NB1, PRV1 ENSG00000204936 CD177 molecule 19 43353659-43363172 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041820, HPA046601 Supported Group enriched 16 bone marrow: 193.4;colon: 159.0;prostate: 110.8;rectum: 184.1 appendix: 10.0 -PSG5 FL-NCA-3, PSG ENSG00000204941 Pregnancy specific beta-1-glycoprotein 5 19 43166256-43186536 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046327 Approved Tissue enriched 107 placenta: 157.4 smooth muscle: 1.4 -ZNF783 DKFZp667J212 ENSG00000204946 Zinc finger family member 783 7 149262171-149297302 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA020375 Uncertain Approved Plasma membrane
Cytosol Mixed spleen: 9.4 -ZNF425 ENSG00000204947 Zinc finger protein 425 7 149102784-149126346 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA020087 Uncertain Supported Nucleus Mixed parathyroid gland: 5.5 -LRRC10B ENSG00000204950 Leucine rich repeat containing 10B 11 61508800-61511018 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA047619 Uncertain Approved Nucleus
Nucleoli Tissue enriched 12 fallopian tube: 46.7 lung: 3.9 -FBXO47 ENSG00000204952 F-box protein 47 17 38936432-38967402 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057438 Uncertain Tissue enriched 72 testis: 7.2 adipose tissue: 0.0 -C12orf73 DKFZp547P055, FLJ13975 ENSG00000204954 Chromosome 12 open reading frame 73 12 103950202-103965708 Predicted secreted proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA038883 Uncertain Approved Plasma membrane
Centrosome
Mitochondria Expressed in all thyroid gland: 17.8 -PCDHGA1 PCDH-GAMMA-A1 ENSG00000204956 Protocadherin gamma subfamily A, 1 5 141330571-141512981 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755, HPA036547 Uncertain Tissue enhanced 0 cerebral cortex: 3.2 testis: 1.4 -BLACE ENSG00000204960 B-cell acute lymphoblastic leukemia expressed 7 155356985-155367934 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041918 Uncertain Not detected bone marrow: 0.3 -PCDHA9 KIAA0345, PCDH-ALPHA9 ENSG00000204961 Protocadherin alpha 9 5 140847463-141012344 Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 1.6 cerebral cortex: 0.6 -PCDHA8 ENSG00000204962 Protocadherin alpha 8 5 140841187-141012344 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044585 Uncertain Not detected cerebral cortex: 0.7 -PCDHA7 CNR4, CNRS4, CRNR4 ENSG00000204963 Protocadherin alpha 7 5 140834248-141012344 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 1.6;testis: 1.3 smooth muscle: 0.3 -PCDHA5 CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5 ENSG00000204965 Protocadherin alpha 5 5 140821604-141012344 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044557 Approved Tissue enriched 10 cerebral cortex: 4.1 endometrium: 0.4 -PCDHA4 CNR1, CNRN1, CRNR1, PCDH-ALPHA4 ENSG00000204967 Protocadherin alpha 4 5 140806929-141012344 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043180, HPA073478 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 4.4 gallbladder: 2.6 -PCDHA2 ENSG00000204969 Protocadherin alpha 2 5 140794852-141012344 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035653 Uncertain Tissue enhanced 0 endometrium: 1.0 cerebral cortex: 0.9 -PCDHA1 ENSG00000204970 Protocadherin alpha 1 5 140786136-141012347 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035969 Approved Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 2.8;testis: 1.6 adrenal gland: 0.4 -TRIM13 DLEU5, Leu5, RFP2, RNF77 ENSG00000204977 Tripartite motif containing 13 13 49995888-50020481 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000367 Approved Expressed in all testis: 140.9 -ERICH4 C19orf69, LOC100170765 ENSG00000204978 Glutamate-rich 4 19 41443158-41444765 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA042632, HPA048484 Uncertain Approved Nucleoplasm
Cytosol Group enriched 22 duodenum: 44.1;kidney: 16.2;small intestine: 43.8 lung: 1.6 -MS4A13 ENSG00000204979 Membrane-spanning 4-domains, subfamily A, member 13 11 60515413-60542721 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045017, HPA063626 Uncertain Tissue enriched 54 testis: 5.3 adipose tissue: 0.0 -PRSS1 TRY1 ENSG00000204983 Protease, serine, 1 (trypsin 1) 7 142749468-142763997 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025487, CAB025538, HPA062452, HPA063471 Supported Tissue enriched 316 pancreas: 81582.7 ovary: 257.8 -SPIRE2 KIAA1832, spir-2 ENSG00000204991 Spire-type actin nucleation factor 2 16 89818179-89871319 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041413, HPA049415 Uncertain Approved Nucleus
Vesicles
Intermediate filaments Mixed stomach: 14.3 -AARD C8orf85, LOC441376 ENSG00000205002 Alanine and arginine rich domain containing protein 8 116938199-116944487 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA068290 Approved Lipid droplets Tissue enriched 8 testis: 42.4 breast: 5.5 -PABPN1L ePABP2 ENSG00000205022 Poly(A) binding protein, nuclear 1-like (cytoplasmic) 16 88863333-88866660 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043415 Uncertain Tissue enhanced 0 adrenal gland: 1.0 bone marrow: 0.5 -OR5D16 ENSG00000205029 Olfactory receptor, family 5, subfamily D, member 16 11 55838752-55839738 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA046711 Uncertain Not detected adipose tissue: 0.0 -OR5L2 HSHTPCRX16, HTPCRX16 ENSG00000205030 Olfactory receptor, family 5, subfamily L, member 2 11 55827219-55828154 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA047524 Uncertain Not detected adipose tissue: 0.0 -PKHD1L1 ENSG00000205038 Polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 8 109362477-109530330 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA044458 Uncertain Group enriched 6 cervix, uterine: 21.2;fallopian tube: 19.5;thyroid gland: 56.9 endometrium: 5.4 -SLFN12L ENSG00000205045 Schlafen family member 12-like 17 35464249-35537861 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA024447 Uncertain Mixed spleen: 7.5 -CLLU1OS ENSG00000205057 Chronic lymphocytic leukemia up-regulated 1 opposite strand 12 92420094-92428148 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 tonsil: 1.0 lymph node: 0.9 -SLC35B4 FLJ14697, YEA4 ENSG00000205060 Solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 7 134289332-134317051 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049779 Approved Mixed cerebral cortex: 17.9 -LGALS7 GAL7, LGALS7A, PIG1, TP53I1 ENSG00000205076 Lectin, galactoside-binding, soluble, 7 19 38770971-38773492 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA001549, CAB032606 Supported Group enriched 6 breast: 17.9;esophagus: 24.4;skin: 27.7 skeletal muscle: 3.6 -SYCE1L MRP2 ENSG00000205078 Synaptonemal complex central element protein 1-like 16 77199397-77213215 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA062464, HPA066691 Validated Intermediate filaments Tissue enriched 6 testis: 23.7 prostate: 3.9 -TMEM231 ALYE870, FLJ22167, JBTS20, MKS11, PRO1886 ENSG00000205084 Transmembrane protein 231 16 75536744-75556286 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042081 Supported Approved Vesicles Tissue enriched 8 fallopian tube: 76.4 thyroid gland: 9.8 -FAM71F2 FAM137B ENSG00000205085 Family with sequence similarity 71, member F2 7 128672288-128687872 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA020513, HPA024248 Supported Approved Nucleoplasm Tissue enriched 7 testis: 9.1 epididymis: 1.3 -C2orf91 ENSG00000205086 Chromosome 2 open reading frame 91 2 41935368-41954266 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042517 Uncertain Tissue enhanced 0 lung: 2.4 adrenal gland: 1.0 -CCNI2 FLJ16793 ENSG00000205089 Cyclin I family, member 2 5 132747445-132754403 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA056288 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Mixed duodenum: 3.9 -TMEM240 C1orf70, SCA21 ENSG00000205090 Transmembrane protein 240 1 1535174-1540453 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 18.6 endometrium: 7.7 -FRG2 FRG2A ENSG00000205097 FSHD region gene 2 4 190024351-190027257 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA039264, HPA047769 Uncertain Not detected parathyroid gland: 0.8 -FAM205A C9orf144B ENSG00000205108 Family with sequence similarity 205, member A 9 34723055-34729467 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA071267 Supported Tissue enriched 319 testis: 39.3 parathyroid gland: 0.1 -CDKL4 ENSG00000205111 Cyclin-dependent kinase-like 4 2 39175646-39229588 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA067895 Uncertain Tissue enriched 8 testis: 5.3 placenta: 0.6 -TMEM88B ENSG00000205116 Transmembrane protein 88B 1 1426128-1427787 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA065743 Supported Tissue enriched 13 cerebral cortex: 11.9 testis: 0.9 -ACCSL ENSG00000205126 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like 11 44047981-44059977 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA046163 Uncertain Not detected testis: 0.4 -C4orf47 LOC441054 ENSG00000205129 Chromosome 4 open reading frame 47 4 185426249-185449826 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043662 Uncertain Approved Vesicles Tissue enhanced 0 fallopian tube: 21.3;testis: 24.2 thyroid gland: 7.8 -TRIQK C8orf83, DKFZp779L1068, LOC286144, PRO0845 ENSG00000205133 Triple QxxK/R motif containing 8 92883530-93017673 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Mixed thyroid gland: 39.1 -SDHAF1 LYRM8 ENSG00000205138 Succinate dehydrogenase complex assembly factor 1 19 35995199-35996315 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA064277 Approved Mitochondria Expressed in all duodenum: 14.2 -ARID3C ENSG00000205143 AT rich interactive domain 3C (BRIGHT-like) 9 34621379-34628107 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 8 liver: 5.9 cerebral cortex: 0.7 -PSENEN PEN2 ENSG00000205155 Presenilin enhancer gamma secretase subunit 19 35745114-35747519 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047435 Approved Expressed in all fallopian tube: 369.9 -C11orf91 ENSG00000205177 Chromosome 11 open reading frame 91 11 33698261-33700801 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA047064, HPA050487 Uncertain Validated Vesicles Tissue enhanced 0 gallbladder: 7.8;testis: 6.9 adipose tissue: 5.7 -FABP9 PERF, PERF15, T-FABP ENSG00000205186 Fatty acid binding protein 9, testis 8 81458341-81461579 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 breast: 1.6;testis: 1.3 adipose tissue: 0.7 -ZBTB10 FLJ12752, RINZF ENSG00000205189 Zinc finger and BTB domain containing 10 8 80485619-80526265 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021554, HPA050569 Supported Validated Nucleoplasm Expressed in all placenta: 25.8 -C4orf46 LOC201725, RCDG1 ENSG00000205208 Chromosome 4 open reading frame 46 4 158666679-158672255 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047287, HPA052670 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 22.3 bone marrow: 8.5 -SCGB2B2 SCGB4A2, SCGBL ENSG00000205209 Secretoglobin, family 2B, member 2 19 34593329-34675699 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA046806 Uncertain Mixed testis: 3.3 -CCDC144NL MGC87631 ENSG00000205212 Coiled-coil domain containing 144 family, N-terminal like 17 20836447-20896140 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA023457 Uncertain Approved Nucleus
Plasma membrane Tissue enriched 7 testis: 4.3 prostate: 0.5 -LGR4 GPR48 ENSG00000205213 Leucine-rich repeat containing G protein-coupled receptor 4 11 27365961-27472775 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030267, HPA054350 Uncertain Approved Microtubule organizing center Expressed in all kidney: 55.7 -PSMB10 beta2i, LMP10, MECL1, MGC1665 ENSG00000205220 Proteasome subunit beta 10 16 67934502-67937087 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030224, HPA030225, CAB034384 Supported Supported Vesicles
Cytosol Expressed in all lymph node: 92.6 -VIT ENSG00000205221 Vitrin 2 36696690-36814792 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 ovary: 35.7 adipose tissue: 18.4 -SPDYE2 MGC119295 ENSG00000205238 Speedy/RINGO cell cycle regulator family member E2 7 102551232-102562308 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044799, HPA051750 Uncertain Tissue enhanced 0 testis: 15.7 skin: 3.9 -E2F4 E2F-4 ENSG00000205250 E2F transcription factor 4, p107/p130-binding 16 67192169-67198918 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054128 Supported Nucleoplasm Expressed in all placenta: 63.7 -PDE7A HCP1 ENSG00000205268 Phosphodiesterase 7A 8 65717510-65842322 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB018770, HPA027340 Approved Expressed in all lymph node: 69.7 -TMEM170B ENSG00000205269 Transmembrane protein 170B 6 11538278-11583524 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA055134 Uncertain Approved Centrosome Tissue enhanced 0 cerebral cortex: 21.4 bone marrow: 16.9 -MUC12 MUC11 ENSG00000205277 Mucin 12, cell surface associated 7 100969623-101018949 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023835 Approved Group enriched 24 colon: 50.6;rectum: 75.4 appendix: 2.6 -CTXN3 ENSG00000205279 Cortexin 3 5 127649044-127658630 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 18 kidney: 77.9 skeletal muscle: 4.3 -MGAT4D GnT1IP ENSG00000205301 MGAT4 family, member D 4 140442262-140498377 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036523 Approved Tissue enriched 67 testis: 48.7 epididymis: 0.7 -SNX2 ENSG00000205302 Sorting nexin 2 5 122774996-122830108 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037400 Approved Validated Endosomes
Lysosomes Expressed in all thyroid gland: 123.8 -SAP25 FLJ00248 ENSG00000205307 Sin3A-associated protein, 25kDa 7 100572228-100573820 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062610 Uncertain Approved Nuclear bodies Tissue enhanced 0 spleen: 49.1 lymph node: 33.2 -NT5M dNT-2, dNT2, mdN ENSG00000205309 5',3'-nucleotidase, mitochondrial 17 17303335-17347663 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043777 Uncertain Mixed testis: 4.8 -SARNP CIP29, Hcc-1, THO1 ENSG00000205323 SAP domain containing ribonucleoprotein 12 55752463-55817756 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030902, HPA030903 Supported Supported Nuclear speckles Expressed in all testis: 91.7 -OR6C68 ENSG00000205327 Olfactory receptor, family 6, subfamily C, member 68 12 55492378-55493316 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected heart muscle: 0.2 -OR6C65 ENSG00000205328 Olfactory receptor, family 6, subfamily C, member 65 12 55400430-55401505 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -OR6C3 OST709 ENSG00000205329 Olfactory receptor, family 6, subfamily C, member 3 12 55331701-55332636 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -OR6C1 OST267 ENSG00000205330 Olfactory receptor, family 6, subfamily C, member 1 12 55320561-55321624 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -ADGRG1 GPR56, TM7LN4, TM7XN1 ENSG00000205336 Adhesion G protein-coupled receptor G1 16 57610652-57665580 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046065 Uncertain Expressed in all thyroid gland: 348.2 -IPO7 Imp7, RANBP7 ENSG00000205339 Importin 7 11 9384622-9448126 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019002, HPA056590 Approved Approved Validated Nucleoplasm
Cytosol Expressed in all thyroid gland: 89.6 -PRR13 DKFZP564J157, FLJ23818 ENSG00000205352 Proline rich 13 12 53441605-53446645 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039396, HPA046219 Uncertain Validated Nucleoplasm Expressed in all small intestine: 525.8 -TECPR1 DKFZP434B0335, FLJ23419, FLJ90593, KIAA1358 ENSG00000205356 Tectonin beta-propeller repeat containing 1 7 98214624-98252251 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021061 Approved Supported Vesicles Expressed in all cerebral cortex: 19.2 -MT1H MT1 ENSG00000205358 Metallothionein 1H 16 56669814-56671129 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 kidney: 498.5;small intestine: 342.1;thyroid gland: 541.5 liver: 134.0 -SLCO6A1 CT48, MGC26949, OATP6A1, OATPY ENSG00000205359 Solute carrier organic anion transporter family, member 6A1 5 102371782-102499016 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA054126 Supported Tissue enriched 136 testis: 53.7 placenta: 0.3 -MT1A MT1, MT1S ENSG00000205362 Metallothionein 1A 16 56638666-56750276 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB002161, CAB013056 Approved Tissue enhanced 0 adipose tissue: 254.9 liver: 58.8 -C15orf59 LOC388135, MGC131524 ENSG00000205363 Chromosome 15 open reading frame 59 15 73735431-73752747 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041563 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 56.1 seminal vesicle: 19.5 -MT1M MT1, MT1K ENSG00000205364 Metallothionein 1M 16 56632233-56633986 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enhanced 0 adipose tissue: 108.8 small intestine: 48.5 -CFI C3b-INA, FI, IF, KAF ENSG00000205403 Complement factor I 4 109740694-109802179 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001143, CAB016777, HPA024061 Supported Tissue enhanced 0 liver: 523.8 kidney: 220.0 -OR52E6 ENSG00000205409 Olfactory receptor, family 52, subfamily E, member 6 11 5840928-5841952 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.1 -SAMD9 C7orf5, FLJ20073, KIAA2004 ENSG00000205413 Sterile alpha motif domain containing 9 7 93099513-93118023 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021318, HPA021319 Approved Validated Vesicles
Cytosol Tissue enhanced 0 esophagus: 43.4 spleen: 24.6 -KRT6A CK6C, CK6D, K6C, K6D, KRT6C, KRT6D ENSG00000205420 Keratin 6A, type II 12 52487174-52493257 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045697, HPA061168 Supported Approved Intermediate filaments Tissue enriched 10 esophagus: 5726.3 tonsil: 585.8 -CNEP1R1 C16orf69, FLJ38101, NEP1-R1, TMEM188 ENSG00000205423 CTD nuclear envelope phosphatase 1 regulatory subunit 1 16 50024410-50037088 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042815, HPA077906 Uncertain Supported Cytosol Mixed testis: 32.7 -KRT81 Hb-1, KRTHB1 ENSG00000205426 Keratin 81, type II 12 52285913-52291534 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049778 Supported Tissue enhanced 0 breast: 4.0 placenta: 1.5 -EXOC3L4 C14orf73 ENSG00000205436 Exocyst complex component 3-like 4 14 103100144-103110559 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043661 Uncertain Tissue enhanced 0 duodenum: 19.7 small intestine: 11.0 -KRTAP12-3 KRTAP12.3 ENSG00000205439 Keratin associated protein 12-3 21 44646657-44658341 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected skin: 0.1 -IZUMO3 bA20A20.1, C9orf134 ENSG00000205442 IZUMO family member 3 9 24542952-24545946 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 238 testis: 23.8 adipose tissue: 0.0 -KRTAP10-2 KAP10.2, KAP18.2, KRTAP18-2 ENSG00000205445 Keratin associated protein 10-2 21 44550357-44551505 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -TP53TG3D ENSG00000205456 TP53 target 3D 16 32252719-32255922 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 4.4;testis: 4.7 placenta: 1.2 -TP53TG3C ENSG00000205457 TP53 target 3C 16 33193659-33306938 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 28 epididymis: 5.5;testis: 3.3 placenta: 0.1 -ATP6AP1L ENSG00000205464 ATPase, H+ transporting, lysosomal accessory protein 1-like 5 82279462-82386977 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053771 Approved Approved Nucleoli
Cytosol Mixed testis: 10.3 -CCDC85C ENSG00000205476 Coiled-coil domain containing 85C 14 99500180-99604026 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA058346 Uncertain Approved Nuclear speckles
Cell Junctions Expressed in all esophagus: 31.3 -OR52J3 ENSG00000205495 Olfactory receptor, family 52, subfamily J, member 3 11 5046526-5047461 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -OR51A2 ENSG00000205496 Olfactory receptor, family 51, subfamily A, member 2 11 4954772-4955713 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -OR51A4 ENSG00000205497 Olfactory receptor, family 51, subfamily A, member 4 11 4946159-4947100 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -C2CD4B FAM148B, NLF2 ENSG00000205502 C2 calcium-dependent domain containing 4B 15 62163535-62165283 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046880 Uncertain Tissue enhanced 0 adipose tissue: 15.3 pancreas: 8.1 -RGL3 FLJ32585 ENSG00000205517 Ral guanine nucleotide dissociation stimulator-like 3 19 11384341-11419342 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042763, HPA043615, HPA064578 Uncertain Uncertain Nucleus
Cytosol Group enriched 6 parathyroid gland: 125.5;thyroid gland: 36.8 seminal vesicle: 13.1 -NAP1L4 NAP2 ENSG00000205531 Nucleosome assembly protein 1-like 4 11 2944431-2992377 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011567 Approved Supported Nucleoplasm Expressed in all parathyroid gland: 147.3 -TMSB4X TB4X, TMSB4 ENSG00000205542 Thymosin beta 4, X-linked X 12975108-12977227 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033806 Approved Approved Nucleoplasm
Vesicles
Cytosol Expressed in all lymph node: 11737.0 -TMEM256 C17orf61, MGC40107 ENSG00000205544 Transmembrane protein 256 17 7402975-7404137 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA062732 Approved Vesicles Expressed in all duodenum: 140.8 -C9orf92 Em:AL513424.1 ENSG00000205549 Chromosome 9 open reading frame 92 9 16203935-16276313 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Mixed thyroid gland: 1.3 -CPT1B CPT1-M, M-CPT1 ENSG00000205560 Carnitine palmitoyltransferase 1B (muscle) 22 50568861-50578465 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA029583 Approved Expressed in all heart muscle: 110.6 -SMN2 BCD541, GEMIN1, SMNC, TDRD16B ENSG00000205571 Survival of motor neuron 2, centromeric 5 70049612-70078522 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB009344, HPA045271 Supported Mixed epididymis: 27.2 -SERF1B FAM2B, H4F5C ENSG00000205572 Small EDRK-rich factor 1B (centromeric) 5 70025247-70043113 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA075271 Approved Nuclear bodies Tissue enhanced 0 testis: 48.1 epididymis: 31.6 -HMGN1 FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425 ENSG00000205581 High mobility group nucleosome binding domain 1 21 39342315-39349647 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012260, HPA048694 Supported Supported Nucleus Expressed in all tonsil: 227.6 -DENND6B AFI1B, FAM116B, MGC33692 ENSG00000205593 DENN/MADD domain containing 6B 22 50309030-50327060 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA018934, HPA021653, HPA029570 Uncertain Uncertain Plasma membrane Tissue enhanced 0 fallopian tube: 21.3 cerebral cortex: 12.0 -EIF3CL ENSG00000205609 Eukaryotic translation initiation factor 3, subunit C-like 16 28379579-28403879 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA047097, HPA049495, HPA050112 Supported Approved Cytosol Mixed skin: 24.3 -LCMT1 CGI-68, PPMT1 ENSG00000205629 Leucine carboxyl methyltransferase 1 16 25111729-25178231 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041559, HPA043530 Uncertain Approved Nucleoplasm
Cytosol Expressed in all testis: 59.5 -MFSD2B ENSG00000205639 Major facilitator superfamily domain containing 2B 2 24010081-24063321 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044145 Supported Tissue enriched 9 bone marrow: 7.2 placenta: 0.7 -VCX3B VCX-C ENSG00000205642 Variable charge, X-linked 3B X 8464830-8466510 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044996, HPA049357 Supported Tissue enriched 84 testis: 32.7 breast: 0.3 -CDPF1 C22orf40, LOC150383 ENSG00000205643 Cysteine-rich, DPF motif domain containing 1 22 46244011-46250679 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018823 Uncertain Approved Nucleus
Cytosol Mixed fallopian tube: 7.0 -HTN3 HIS2 ENSG00000205649 Histatin 3 4 70028413-70036538 Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level CAB073541 Supported Uncertain Vesicles Tissue enriched 1662 salivary gland: 47809.1 ovary: 28.7 -LIN52 C14orf46 ENSG00000205659 Lin-52 DREAM MuvB core complex component 14 74084796-74201235 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000900, HPA001777 Uncertain Approved Nuclear speckles Mixed kidney: 17.2 -ARSH ENSG00000205667 Arylsulfatase family, member H X 3006613-3033571 Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.9 -ACOT6 C14orf42 ENSG00000205669 Acyl-CoA thioesterase 6 14 73610945-73619888 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058258 Uncertain Tissue enhanced 0 kidney: 4.8 liver: 3.1 -SMIM11A C21orf51, FAM165B, SMIM11 ENSG00000205670 Small integral membrane protein 11A 21 34375480-34407866 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051321 Uncertain Approved Focal adhesion sites Mixed thyroid gland: 32.0 -TECRL DKFZp313B2333, DKFZp313D0829, GPSN2L, SRD5A2L2, TERL ENSG00000205678 Trans-2,3-enoyl-CoA reductase-like 4 64275257-64409468 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 18 heart muscle: 361.1 skeletal muscle: 20.5 -DPF3 BAF45c, cer-d4, Cerd4, FLJ14079 ENSG00000205683 D4, zinc and double PHD fingers, family 3 14 72619296-72894116 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066790, HPA070601 Supported Validated Nucleoplasm Tissue enhanced 0 ovary: 16.7 parathyroid gland: 10.1 -MANSC4 ENSG00000205693 MANSC domain containing 4 12 27762738-27771276 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA039454, HPA039682 Uncertain Tissue enhanced 0 testis: 3.2 placenta: 0.8 -LYRM5 ENSG00000205707 LYR motif containing 5 12 25195216-25209645 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA044255 Approved Approved Microtubule organizing center Expressed in all testis: 111.5 -C17orf107 ENSG00000205710 Chromosome 17 open reading frame 107 17 4899418-4902932 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA069713 Uncertain Approved Nucleus Mixed salivary gland: 5.7 -MBD3L4 ENSG00000205718 Methyl-CpG binding domain protein 3-like 4 19 7037748-7040179 Predicted intracellular proteins No evidence No evidence No evidence HPA051259 Uncertain Not detected adipose tissue: 0.0 -ITSN1 ITSN, MGC134948, MGC134949, SH3D1A, SH3P17 ENSG00000205726 Intersectin 1 (SH3 domain protein) 21 33642400-33899861 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018007 Approved Supported Plasma membrane Expressed in all adipose tissue: 61.3 -ITPRIPL2 FLJ22994, LOC162073, MGC126798, MGC126800 ENSG00000205730 Inositol 1,4,5-trisphosphate receptor interacting protein-like 2 16 19113932-19121629 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042011 Approved Centrosome Expressed in all skin: 27.9 -DENND1C FAM31C, FLJ22757 ENSG00000205744 DENN/MADD domain containing 1C 19 6467207-6482557 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042758, HPA042839 Supported Tissue enhanced 0 appendix: 29.2;lymph node: 37.6;spleen: 32.3 tonsil: 14.5 -SLCO1B7 LST3, SLC21A21 ENSG00000205754 Solute carrier organic anion transporter family, member 1B7 (non-functional) 12 21015696-21092745 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA050892 Uncertain Tissue enriched 21 breast: 42.5 liver: 2.0 -CRLF2 CRL2, TSLPR ENSG00000205755 Cytokine receptor-like factor 2 X 1187549-1212750 Cancer-related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 appendix: 2.1;gallbladder: 2.0 bone marrow: 1.0 -CRYZL1 4P11, QOH-1 ENSG00000205758 Crystallin, zeta (quinone reductase)-like 1 21 33589341-33643926 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019120, HPA029399, CAB034129 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 63.3 -C5orf51 LOC285636 ENSG00000205765 Chromosome 5 open reading frame 51 5 41904188-41921636 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043779, HPA063816 Uncertain Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 26.6 -GAGE1 CT4.1 ENSG00000205777 G antigen 1 X 49589496-49608536 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enriched 245 testis: 182.5 stomach: 0.7 -ARRDC5 ENSG00000205784 Arrestin domain containing 5 19 4890437-4902867 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enriched 8 testis: 18.2 spleen: 2.3 -CYS1 ENSG00000205795 Cystin 1 2 10056780-10080944 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 6 kidney: 100.7 ovary: 15.7 -PLPP6 FLJ46512, FLJ90191, PDP1, PPAPDC2 ENSG00000205808 Phospholipid phosphatase 6 9 4662315-4665258 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018096 Approved Approved Nucleoplasm
Vesicles Mixed prostate: 26.8 -KLRC2 CD159c, NKG2-C ENSG00000205809 Killer cell lectin-like receptor subfamily C, member 2 12 10426854-10442300 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058052 Approved Plasma membrane Group enriched 6 cerebral cortex: 17.4;spleen: 8.3 stomach: 2.0 -KLRC3 NKG2-E ENSG00000205810 Killer cell lectin-like receptor subfamily C, member 3 12 10412312-10420595 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039910, HPA062570 Approved Uncertain Vesicles Tissue enhanced 0 cerebral cortex: 9.3;spleen: 6.3 lymph node: 2.3 -C16orf96 ENSG00000205832 Chromosome 16 open reading frame 96 16 4556490-4600714 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA042009, HPA042058 Uncertain Tissue enriched 21 testis: 10.9 cerebral cortex: 0.5 -GMNC GEMC1 ENSG00000205835 Geminin coiled-coil domain containing 3 190852877-190892429 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043663 Uncertain Tissue enriched 5 fallopian tube: 9.4 testis: 1.8 -TTC23L FLJ25439 ENSG00000205838 Tetratricopeptide repeat domain 23-like 5 34838833-34899456 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA037807 Supported Tissue enriched 7 testis: 37.8 fallopian tube: 5.3 -CLEC6A CLECSF10, dectin-2 ENSG00000205846 C-type lectin domain family 6, member A 12 8455926-8478330 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 appendix: 1.6;lung: 1.5 lymph node: 0.8 -RFPL3S NCRNA00005, RFPL3-AS, RFPL3-AS1 ENSG00000205853 RFPL3 antisense 22 32359906-32382052 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 24 testis: 98.1 cerebral cortex: 4.1 -C22orf42 ENSG00000205856 Chromosome 22 open reading frame 42 22 32149006-32159322 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA019531 Approved Tissue enriched 10 testis: 10.7 prostate: 1.0 -NANOGNB ENSG00000205857 NANOG neighbor homeobox 12 7765216-7774121 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA060371 Uncertain Not detected testis: 0.5 -LRRC72 ENSG00000205858 Leucine rich repeat containing 72 7 16526880-16581568 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA020554 Uncertain Tissue enriched 29 testis: 4.3 cervix: 0.1 -C1QTNF9B CTRP9B ENSG00000205863 C1q and tumor necrosis factor related protein 9B 13 23891099-23902655 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA056632 Uncertain Group enriched 5 prostate: 15.4;skin: 22.6;testis: 27.6 epididymis: 4.0 -KRTAP5-6 KRTAP5.6 ENSG00000205864 Keratin associated protein 5-6 11 1697195-1697755 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected placenta: 0.6 -KRTAP5-2 KRTAP5-8, KRTAP5.2 ENSG00000205867 Keratin associated protein 5-2 11 1597177-1598294 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 3.6 parathyroid gland: 1.6 -KRTAP5-1 KRN1L, KRTAP5.1 ENSG00000205869 Keratin associated protein 5-1 11 1584342-1585283 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected epididymis: 0.3 -DEFB134 ENSG00000205882 Defensin, beta 134 8 11993174-11996312 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 8 epididymis: 36.4 testis: 4.6 -DEFB135 ENSG00000205883 Defensin, beta 135 8 11982321-11984590 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 189 epididymis: 85.3 testis: 0.4 -DEFB136 DEFB137 ENSG00000205884 Defensin, beta 136 8 11973937-11974599 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 9 epididymis: 3.7 seminal vesicle: 0.4 -BHLHA9 bHLHa9, BHLHF42 ENSG00000205899 Basic helix-loop-helix family, member a9 17 1270559-1271460 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level HPA062632 Uncertain Not detected cerebral cortex: 0.8 -ZNF316 ENST00000305834, MZF-3 ENSG00000205903 Zinc finger protein 316 7 6637322-6656432 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all parathyroid gland: 50.0 -DAZ4 ENSG00000205916 Deleted in azoospermia 4 Y 24833843-24907040 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047113 Approved Group enriched 41 stomach: 23.1;testis: 21.4 skin: 0.5 -ONECUT3 ENSG00000205922 One cut homeobox 3 19 1752373-1780988 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA059936 Supported Nucleoplasm Tissue enhanced 0 stomach: 4.1 gallbladder: 1.0 -CEMP1 CP-23 ENSG00000205923 Cementum protein 1 16 2530035-2531417 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057658 Approved Mixed skin: 5.7 -OLIG2 BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17 ENSG00000205927 Oligodendrocyte lineage transcription factor 2 21 33025845-33029196 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA003254, CAB019381 Supported Uncertain Nucleoplasm
Plasma membrane Tissue enriched 239 cerebral cortex: 91.2 duodenum: 0.3 -C21orf62 B37, C21orf120, PRED81 ENSG00000205929 Chromosome 21 open reading frame 62 21 32790674-32813743 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA016899, CAB034173 Approved Tissue enhanced 0 epididymis: 7.0;kidney: 5.4;ovary: 12.5 prostate: 3.7 -RNPS1 ENSG00000205937 RNA binding protein S1, serine-rich domain 16 2253116-2268412 Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044014 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 144.2 -DAZ2 MGC126442, pDP1678 ENSG00000205944 Deleted in azoospermia 2 Y 23219434-23291356 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047113 Approved Group enriched 28 stomach: 15.8;testis: 7.2 skin: 0.4 -NYNRIN CGIN1, FLJ11811, KIAA1305 ENSG00000205978 NYN domain and retroviral integrase containing 14 24398786-24419288 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA018945 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Mixed ovary: 42.6 -DNAJC19 Pam18, Tim14, TIMM14 ENSG00000205981 DnaJ (Hsp40) homolog, subfamily C, member 19 3 180983709-180989774 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037782 Approved Expressed in all kidney: 52.6 -IFITM5 BRIL, fragilis4, Hrmp1 ENSG00000206013 Interferon induced transmembrane protein 5 11 298200-299526 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA039258 Uncertain Tissue enhanced 0 epididymis: 1.1 bone marrow: 0.5 -SMIM21 C18orf62 ENSG00000206026 Small integral membrane protein 21 18 75409476-75427703 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA041686 Supported Tissue enriched 56 testis: 5.5 adipose tissue: 0.0 -C18orf63 DKFZP781G0119 ENSG00000206043 Chromosome 18 open reading frame 63 18 74315813-74359187 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042233 Approved Mitochondria Tissue enriched 61 testis: 17.7 breast: 0.2 -DEFA1 DEF1, DEFA2, HNP-1, MRS ENSG00000206047 Defensin, alpha 1 8 6977649-6980080 Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level CAB032548, HPA052517 Supported Tissue enriched 284 bone marrow: 15680.7 skin: 55.3 -DOK6 DOK5L, HsT3226, MGC20785 ENSG00000206052 Docking protein 6 18 69401055-69849087 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041099, HPA063534 Approved Approved Focal adhesion sites
Cytosol Tissue enhanced 0 cerebral cortex: 21.1 placenta: 8.4 -HN1L C16orf34, FLJ13092, KIAA1426, L11 ENSG00000206053 Hematological and neurological expressed 1-like 16 1678256-1702280 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041888, HPA041908 Approved Validated Plasma membrane
Cytosol Expressed in all fallopian tube: 100.6 -TMEM211 bA9F11.1 ENSG00000206069 Transmembrane protein 211 22 24935110-24946695 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA066784 Uncertain Tissue enhanced 0 cervix, uterine: 4.5;stomach: 3.4 salivary gland: 1.9 -SERPINB11 EPIPIN ENSG00000206072 Serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 18 63647579-63726432 Plasma proteins, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 6 esophagus: 28.8;prostate: 65.8 tonsil: 7.5 -SERPINB4 LEUPIN, PI11, SCCA-2, SCCA1, SCCA2 ENSG00000206073 Serpin peptidase inhibitor, clade B (ovalbumin), member 4 18 63637259-63644298 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048341, HPA049988, HPA055992 Supported Group enriched 6 esophagus: 98.6;urinary bladder: 20.1 skin: 9.4 -SERPINB5 maspin, PI5 ENSG00000206075 Serpin peptidase inhibitor, clade B (ovalbumin), member 5 18 63476761-63505085 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009570, HPA019025, HPA019132, HPA020136 Supported Supported Vesicles Group enriched 6 esophagus: 221.1;skin: 262.5 breast: 43.8 -ZDHHC11B ENSG00000206077 Zinc finger, DHHC-type containing 11B 5 710360-766952 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA057886, HPA069008 Uncertain Approved Lipid droplets Mixed cerebral cortex: 6.2 -KRTAP19-8 ENSG00000206102 Keratin associated protein 19-8 21 31038159-31038476 Predicted intracellular proteins No evidence No evidence No evidence Not detected testis: 0.8 -KRTAP20-3 KAP19D, KAP20.3, KRTAP19P4 ENSG00000206104 Keratin associated protein 20-3 21 30642864-30643136 Predicted intracellular proteins No evidence No evidence No evidence HPA053598 Uncertain Not detected adipose tissue: 0.0 -KRTAP20-4 KAP20.4 ENSG00000206105 Keratin associated protein 20-4 21 30620627-30620850 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 36 testis: 3.5 adipose tissue: 0.0 -KRTAP22-2 KAP22.2 ENSG00000206106 Keratin associated protein 22-2 21 30590105-30590397 Predicted intracellular proteins No evidence No evidence No evidence Not detected skin: 0.2 -KRTAP27-1 ENSG00000206107 Keratin associated protein 27-1 21 30337013-30337694 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA021522, HPA048826 Approved Not detected epididymis: 0.0 -CFAP99 ENSG00000206113 Cilia- and flagella-associated protein 99 4 2418974-2462942 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Group enriched 6 fallopian tube: 3.2;testis: 3.8 adrenal gland: 0.6 -GOLGA8O ENSG00000206127 Golgin A8 family, member O 15 32445106-32455634 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 8.6;thyroid gland: 5.3 epididymis: 3.7 -RNASE13 RAL1 ENSG00000206150 Ribonuclease, RNase A family, 13 (non-active) 14 21032820-21034785 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 242 epididymis: 374.0 salivary gland: 1.5 -HBA1 HBA-T3 ENSG00000206172 Hemoglobin, alpha 1 16 176680-177522 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB032534, HPA043780 Supported Tissue enriched 5 bone marrow: 17168.0 placenta: 3411.4 -HBM HBAP2, HBK ENSG00000206177 Hemoglobin, mu 16 153892-166768 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 30 bone marrow: 269.9 placenta: 9.1 -TCEB3B HsT832, TCEB3L ENSG00000206181 Transcription elongation factor B polypeptide 3B (elongin A2) 18 47032572-47035621 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041009, HPA043501, HPA048971, HPA049178, HPA050086 Approved Tissue enriched 42 testis: 4.3 parathyroid gland: 0.1 -ATP10A ATP10C, ATPVA, ATPVC, KIAA0566 ENSG00000206190 ATPase, class V, type 10A 15 25677273-25865172 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA041496, HPA042509 Uncertain Mixed lung: 10.5 -ANKUB1 C3orf16 ENSG00000206199 Ankyrin repeat and ubiquitin domain containing 1 3 149761105-149968385 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053749 Uncertain Tissue enriched 5 fallopian tube: 8.7 lung: 1.6 -TSSK2 FLJ38613, SPOGA2, STK22B ENSG00000206203 Testis-specific serine kinase 2 22 19130808-19132623 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 288 testis: 120.0 ovary: 0.4 -PRR23A ENSG00000206260 Proline rich 23A 3 139005468-139006268 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA047473 Uncertain Tissue enriched 8 testis: 1.9 ovary: 0.2 -FOXL2NB C3orf72, FLJ43329 ENSG00000206262 FOXL2 neighbor 3 138947234-138953451 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA061017, HPA071790 Supported Nucleoli fibrillar center Tissue enhanced 0 endometrium: 29.1;ovary: 50.7;parathyroid gland: 63.1 fallopian tube: 19.5 -HCG27 bCX101P6.9, bPG299F13.9, bQB115I13.2, FLJ40123 ENSG00000206344 HLA complex group 27 (non-protein coding) 6 31197760-31203968 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed spleen: 6.6 -COL6A6 ENSG00000206384 Collagen, type VI, alpha 6 3 130560334-130678155 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045239 Uncertain Tissue enhanced 0 lung: 11.2 breast: 2.9 -RAB12 ENSG00000206418 RAB12, member RAS oncogene family 18 8609445-8639381 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040727 Approved Approved Vesicles Expressed in all skeletal muscle: 67.4 -LRRC30 ENSG00000206422 Leucine rich repeat containing 30 18 7231125-7232047 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA041039 Uncertain Tissue enriched 10 skeletal muscle: 5.6 esophagus: 0.5 -TMEM200C TTMA ENSG00000206432 Transmembrane protein 200C 18 5882072-5895955 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA047253, HPA050490 Uncertain Approved Microtubules Tissue enhanced 0 adrenal gland: 3.1;cerebral cortex: 3.5 salivary gland: 1.8 -TXNRD3NB TR2IT1, TXNRD3IT1, TXNRD3NT1 ENSG00000206483 Thioredoxin reductase 3 neighbor 3 126571789-126572636 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA058257 Uncertain Not detected testis: 0.2 -HLA-A ENSG00000206503 Major histocompatibility complex, class I, A 6 29941260-29945884 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB078470 Supported Golgi apparatus
Plasma membrane Mixed gallbladder: 342.4 -HACD2 PTPLB ENSG00000206527 3-hydroxyacyl-CoA dehydratase 2 3 123490820-123585185 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB019282 Approved Expressed in all adipose tissue: 68.9 -CFAP44 FLJ11142, WDR52 ENSG00000206530 Cilia and flagella associated protein 44 3 113286930-113441610 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067258 Uncertain Tissue enhanced 0 testis: 24.9 fallopian tube: 19.2 -CD200R1L CD200R2, CD200RLa ENSG00000206531 CD200 receptor 1-like 3 112815709-112846856 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 46 testis: 4.9 epididymis: 0.1 -LNP1 NP3 ENSG00000206535 Leukemia NUP98 fusion partner 1 3 100401193-100456319 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047926 Approved Nuclear speckles
Vesicles
Cytosol Tissue enriched 6 testis: 47.7 cerebral cortex: 7.6 -OR5K3 ENSG00000206536 Olfactory receptor, family 5, subfamily K, member 3 3 98390666-98391631 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -VGLL3 VGL-3 ENSG00000206538 Vestigial-like family member 3 3 86937969-86991119 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054983 Approved Approved Nucleoli
Cytosol Tissue enhanced 0 placenta: 57.4 adipose tissue: 24.2 -PRSS50 CT20, TSP50 ENSG00000206549 Protease, serine, 50 3 46712116-46812574 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008977, HPA040768 Supported Tissue enriched 6 testis: 41.7 epididymis: 7.1 -TRIM71 LIN-41, LIN41 ENSG00000206557 Tripartite motif containing 71, E3 ubiquitin protein ligase 3 32818018-32897826 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA038141, HPA038142 Uncertain Approved Plasma membrane
Actin filaments
Focal adhesion sites Tissue enriched 8 testis: 9.1 lung: 1.1 -ZCWPW2 ZCW2 ENSG00000206559 Zinc finger, CW type with PWWP domain 2 3 28349146-28538122 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035035, HPA039839 Uncertain Approved Nuclear speckles Tissue enhanced 0 testis: 21.1 thyroid gland: 6.2 -ANKRD28 KIAA0379, PITK, PP6-ARS-A, PPP1R65 ENSG00000206560 Ankyrin repeat domain 28 3 15667236-15859771 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all epididymis: 35.7 -COLQ EAD ENSG00000206561 Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 3 15450133-15521751 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045876 Approved Plasma membrane
Cell Junctions Tissue enhanced 0 parathyroid gland: 19.2 fallopian tube: 17.4 -METTL6 MGC24132 ENSG00000206562 Methyltransferase like 6 3 15381275-15440566 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035166 Uncertain Approved Vesicles Expressed in all testis: 33.7 -XKR4 KIAA1889 ENSG00000206579 XK, Kell blood group complex subunit-related family, member 4 8 55102389-55542054 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA025072, HPA028083 Uncertain Tissue enriched 6 cerebral cortex: 4.7 seminal vesicle: 0.8 -GPX3 ENSG00000211445 Glutathione peroxidase 3 5 151020438-151028993 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB069456 Uncertain Expressed in all kidney: 11584.2 -DIO2 SelY, TXDI2 ENSG00000211448 Deiodinase, iodothyronine, type II 14 80197527-80387757 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA029544, HPA048002 Supported Nucleoplasm
Cytosol Group enriched 6 cervix, uterine: 268.3;thyroid gland: 599.1 esophagus: 70.6 -C11orf31 SELH ENSG00000211450 Chromosome 11 open reading frame 31 11 57741250-57743554 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048362 Uncertain Approved Nucleus
Nucleoli Expressed in all adrenal gland: 69.9 -DIO1 TXDI1 ENSG00000211452 Deiodinase, iodothyronine, type I 1 53891239-53911086 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 30 kidney: 146.4;liver: 94.7;thyroid gland: 433.9 fallopian tube: 7.5 -STK38L KIAA0965, NDR2 ENSG00000211455 Serine/threonine kinase 38 like 12 27243968-27325959 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038623, HPA051324 Approved Approved Cytosol Expressed in all parathyroid gland: 64.3 -SACM1L KIAA0851, SAC1 ENSG00000211456 SAC1 suppressor of actin mutations 1-like (yeast) 3 45689056-45745424 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039573, HPA069869 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 67.2 -TSN BCLF-1, REHF-1, TRSLN ENSG00000211460 Translin 2 121737103-121767853 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059561 Uncertain Expressed in all testis: 40.9 -SLC48A1 FLJ20489, hHRG-1, HRG1 ENSG00000211584 Solute carrier family 48 (heme transporter), member 1 12 47753916-47782753 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA073994 Supported Vesicles Expressed in all thyroid gland: 79.4 -TSSK1B FKSG81, SPOGA4, STK22D, TSSK1 ENSG00000212122 Testis-specific serine kinase 1B 5 113432554-113435031 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027827 Supported Tissue enriched 222 testis: 62.0 parathyroid gland: 0.2 -PRR22 MGC24975 ENSG00000212123 Proline rich 22 19 5782960-5784765 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044157 Approved Approved Nucleus
Vesicles
Cytosol Tissue enhanced 0 testis: 22.0 skin: 4.9 -TAS2R19 T2R19, T2R23, TAS2R23, TAS2R48 ENSG00000212124 Taste receptor, type 2, member 19 12 11021619-11022620 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level No evidence Evidence at transcript level Not detected ovary: 0.2 -TAS2R50 T2R51 ENSG00000212126 Taste receptor, type 2, member 50 12 10985913-10986912 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -TAS2R14 T2R14, TRB1 ENSG00000212127 Taste receptor, type 2, member 14 12 10937406-11171573 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed epididymis: 1.2 -TAS2R13 T2R13, TRB3 ENSG00000212128 Taste receptor, type 2, member 13 12 10907926-10909562 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.0 -ZRSR1 U2AF1-RS1, U2AF1L1, U2AF1P, U2AF1RS1, U2AFBPL, ZC3H21 ENSG00000212643 Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 5 112891422-112893094 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed epididymis: 1.9 -KRTAP16-1 KAP16.1 ENSG00000212657 Keratin associated protein 16-1 17 41307700-41309253 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA070954 Supported Not detected bone marrow: 0.3 -KRTAP29-1 KAP29.2 ENSG00000212658 Keratin associated protein 29-1 17 41301826-41302851 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Not detected tonsil: 0.1 -KRTAP9-6 KAP9.6, KRTAP9L2 ENSG00000212659 Keratin associated protein 9-6 17 41265339-41266641 Predicted intracellular proteins No evidence No evidence No evidence Not detected skin: 0.1 -CTAGE1 CT21.1, CT21.2, CTAGE, cTAGE-1, cTAGE-2 ENSG00000212710 Cutaneous T-cell lymphoma-associated antigen 1 18 22413601-22417915 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000387, HPA000922, CAB016204 Uncertain Tissue enriched 50 testis: 5.0 epididymis: 0.0 -C17orf51 FLJ12977, FLJ31874, FLJ33618 ENSG00000212719 Chromosome 17 open reading frame 51 17 21524790-21574458 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052106 Approved Approved Nucleoplasm
Nuclear bodies
Vesicles Tissue enhanced 0 cerebral cortex: 16.7 testis: 8.6 -KRTAP4-11 KAP4.11, KAP4.14, KRTAP4-14 ENSG00000212721 Keratin associated protein 4-11 17 41117181-41118360 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -KRTAP4-9 KAP4.9 ENSG00000212722 Keratin associated protein 4-9 17 41105332-41106488 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -KRTAP2-3 KAP2.3 ENSG00000212724 Keratin associated protein 2-3 17 41059240-41060114 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA059203 Supported Not detected adipose tissue: 0.0 -KRTAP2-1 KAP2.1A ENSG00000212725 Keratin associated protein 2-1 17 41046541-41047316 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA059203 Supported Not detected epididymis: 0.0 -FAM127C CXX1c, MAR8B ENSG00000212747 Family with sequence similarity 127, member C X 135020504-135022529 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed smooth muscle: 17.5 -OR2A42 ENSG00000212807 Olfactory receptor, family 2, subfamily A, member 42 7 144231911-144232843 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA058272 Uncertain Not detected thyroid gland: 0.8 -RNF208 DKFZP761H1710 ENSG00000212864 Ring finger protein 208 9 137220247-137221581 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA021256, HPA021429 Uncertain Supported Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 25.2 adrenal gland: 7.4 -KRTAP3-3 KAP3.3 ENSG00000212899 Keratin associated protein 3-3 17 40993430-40994133 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level HPA042992 Approved Not detected breast: 0.1 -KRTAP3-2 KAP3.2 ENSG00000212900 Keratin associated protein 3-2 17 40999193-40999894 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042992 Approved Tissue enriched 7 esophagus: 3.3 skin: 0.5 -KRTAP3-1 KAP3.1 ENSG00000212901 Keratin associated protein 3-1 17 41008521-41019324 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Not detected adipose tissue: 0.0 -MT-ND4L MTND4L, NAD4L, ND4L ENSG00000212907 Mitochondrially encoded NADH dehydrogenase 4L MT 10470-10766 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA075648 Approved Mitochondria Expressed in all heart muscle: 23512.4 -MAP10 KIAA1383, MTR120 ENSG00000212916 Microtubule-associated protein 10 1 232804892-232808407 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA052496 Approved Mixed testis: 5.8 -KRTAP12-4 KRTAP12.4 ENSG00000212933 Keratin associated protein 12-4 21 44654213-44654659 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.1 -KRTAP10-3 KAP10.3, KAP18.3, KRTAP18-3 ENSG00000212935 Keratin associated protein 10-3 21 44557790-44558760 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -KRTAP6-3 KAP6.3 ENSG00000212938 Keratin associated protein 6-3 21 30592440-30593075 Predicted intracellular proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -POU5F1B OTF3C, OTF3P1, POU5F1P1 ENSG00000212993 POU class 5 homeobox 1B 8 127414290-127420069 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level No evidence HPA058267 Supported Nucleoplasm Not detected parathyroid gland: 0.7 -ZNF580 ENSG00000213015 Zinc finger protein 580 19 55635016-55643469 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054058 Approved Approved Nucleus Expressed in all parathyroid gland: 37.6 -ZNF611 MGC5384 ENSG00000213020 Zinc finger protein 611 19 52702813-52735073 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed fallopian tube: 10.5 -KLK9 KLK-L3 ENSG00000213022 Kallikrein-related peptidase 9 19 51003111-51009634 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level CAB025049 Uncertain Not detected tonsil: 0.8 -SYT3 ENSG00000213023 Synaptotagmin III 19 50621307-50668394 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 10 cerebral cortex: 17.1 testis: 1.7 -NUP62 DKFZp547L134, FLJ20822, FLJ43869, IBSN, MGC841, p62, SNDI ENSG00000213024 Nucleoporin 62kDa 19 49906825-49929763 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005435, CAB020724 Supported Supported Nuclear membrane
Vesicles Expressed in all testis: 76.8 -SPHAR ENSG00000213029 S-phase response (cyclin related) 1 229304857-229305504 Predicted intracellular proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -CGB8 ENSG00000213030 Chorionic gonadotropin, beta polypeptide 8 19 49047638-49049106 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038925, HPA038934 Supported Approved Cytosol Tissue enriched 92 placenta: 29.2 parathyroid gland: 0.3 -DENND1B C1orf218, FAM31B, FLJ20054, MGC27044 ENSG00000213047 DENN/MADD domain containing 1B 1 197504748-197775696 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042586 Uncertain Supported Nuclear speckles
Cytosol Expressed in all parathyroid gland: 11.5 -SFT2D2 dJ747L4.C1.2, UNQ512 ENSG00000213064 SFT2 domain containing 2 1 168225938-168253025 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042207 Approved Mixed bone marrow: 21.3 -FGFR1OP FOP ENSG00000213066 FGFR1 oncogene partner 6 166999182-167052713 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071876 Supported Centrosome Expressed in all testis: 104.8 -FAM106A FLJ11800 ENSG00000213077 Family with sequence similarity 106, member A 17 18524566-18526846 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA056425 Uncertain Tissue enhanced 0 testis: 7.3 placenta: 1.6 -SCAF8 KIAA1116, RBM16 ENSG00000213079 SR-related CTD-associated factor 8 6 154733325-154834244 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035601, HPA035602 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 44.4 -CFAP45 CCDC19, NESG1 ENSG00000213085 Cilia and flagella associated protein 45 1 159872364-159900163 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042204, HPA043618 Supported Validated Nucleoplasm Group enriched 7 fallopian tube: 70.6;testis: 38.8 lung: 7.7 -ACKR1 CCBP1, CD234, DARC, Dfy, FY, GPD ENSG00000213088 Atypical chemokine receptor 1 (Duffy blood group) 1 159203307-159206500 Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA016421, HPA017672 Supported Mixed adipose tissue: 111.8 -ZNF254 BMZF-5, HD-ZNF1, ZNF539, ZNF91L ENSG00000213096 Zinc finger protein 254 19 24033405-24129961 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed thyroid gland: 29.2 -TCTEX1D2 MGC33212 ENSG00000213123 Tctex1 domain containing 2 3 196291219-196318299 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049555 Uncertain Approved Cytosol Tissue enhanced 0 fallopian tube: 48.5 testis: 38.7 -CRYGS CRYG8 ENSG00000213139 Crystallin, gamma S 3 186538441-186546702 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035103 Uncertain Uncertain Cytosol Mixed spleen: 4.2 -CRIP1 CRIP ENSG00000213145 Cysteine-rich protein 1 (intestinal) 14 105486317-105488947 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042462 Approved Uncertain Nuclear speckles
Centrosome
Cytosol Expressed in all small intestine: 557.9 -KLHL23 FLJ37812, MGC22679, MGC2610 ENSG00000213160 Kelch-like family member 23 2 169694488-169776989 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047593 Approved Nucleoplasm
Actin filaments Expressed in all endometrium: 42.5 -LINGO4 LRRN6D ENSG00000213171 Leucine rich repeat and Ig domain containing 4 1 151800264-151806154 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060781 Uncertain Tissue enhanced 0 adrenal gland: 2.3;skeletal muscle: 4.1 fallopian tube: 1.0 -FAM24B AC073585.2, MGC45962 ENSG00000213185 Family with sequence similarity 24, member B 10 122849078-122879641 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA052490 Uncertain Tissue enhanced 0 kidney: 13.7 testis: 11.4 -TRIM59 Mrf1, RNF104, TRIM57, TSBF1 ENSG00000213186 Tripartite motif containing 59 3 160432445-160485773 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017750 Uncertain Approved Rods & Rings Mixed cerebral cortex: 18.4 -MLLT11 AF1Q ENSG00000213190 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 1 151057758-151068497 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000540 Uncertain Supported Nucleoplasm
Cytosol Tissue enhanced 0 cerebral cortex: 122.9 parathyroid gland: 26.9 -ASIC3 ACCN3, DRASIC, TNaC1 ENSG00000213199 Acid sensing (proton gated) ion channel 3 7 151048292-151052756 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049155 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 testis: 8.1 cerebral cortex: 5.8 -GIMAP1 HIMAP1, IAN2, IMAP1, IMAP38 ENSG00000213203 GTPase, IMAP family member 1 7 150716557-150724284 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044887, HPA053441 Uncertain Supported Endoplasmic reticulum Tissue enhanced 0 spleen: 33.3 lymph node: 21.6 -CCDC183 bA216L13.7, KIAA1984, MGC15438 ENSG00000213213 Coiled-coil domain containing 183 9 136796350-136807741 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043812 Uncertain Tissue enriched 81 testis: 11.7 rectum: 0.1 -ARHGEF35 ARHGEF5L, CTAGE4, FLJ43692 ENSG00000213214 Rho guanine nucleotide exchange factor (GEF) 35 7 144186083-144195655 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044188, HPA045619, HPA045699 Supported Mixed thyroid gland: 44.7 -CSH2 CS-2, CSB, hCS-B ENSG00000213218 Chorionic somatomammotropin hormone 2 17 63872012-63881863 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043715 Supported Tissue enriched 195 placenta: 3928.4 smooth muscle: 20.1 -DNLZ bA413M3.2, C9orf151, HEP, RP11-413M3.2, TIMM15, ZIM17 ENSG00000213221 DNL-type zinc finger 9 136359480-136363789 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062738 Validated Nucleoplasm
Mitochondria Expressed in all cerebral cortex: 13.7 -TCL1B TML1 ENSG00000213231 T-cell leukemia/lymphoma 1B 14 95686417-95692643 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053163 Uncertain Approved Cytosol Tissue enhanced 0 lymph node: 2.5;testis: 3.6;tonsil: 2.3 placenta: 1.2 -SUPT4H1 Spt4, SPT4H, Supt4a, SUPT4H ENSG00000213246 SPT4 homolog, DSIF elongation factor subunit 17 58345175-58353093 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059748 Approved Nucleus Expressed in all lymph node: 83.7 -TSGA13 ENSG00000213265 Testis specific, 13 7 130668648-130687432 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA022968 Uncertain Group enriched 59 placenta: 5.5;testis: 21.0 epididymis: 0.2 -NRAS N-ras ENSG00000213281 Neuroblastoma RAS viral (v-ras) oncogene homolog 1 114704469-114716894 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010157, HPA049830 Uncertain Expressed in all placenta: 39.1 -LTC4S MGC33147 ENSG00000213316 Leukotriene C4 synthase 5 179793980-179796647 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed fallopian tube: 7.4 -ANKRD39 MGC41816 ENSG00000213337 Ankyrin repeat domain 39 2 96836611-96858095 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042678 Approved Approved Nucleoplasm
Vesicles Expressed in all cerebral cortex: 17.2 -QTRT1 TGT ENSG00000213339 Queuine tRNA-ribosyltransferase 1 19 10701430-10713437 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042695, HPA048651, HPA049440 Approved Approved Mitochondria Expressed in all thyroid gland: 25.4 -CHUK IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 ENSG00000213341 Conserved helix-loop-helix ubiquitous kinase 10 100188298-100229619 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001402, CAB004240, CAB018564 Approved Supported Nucleoplasm
Vesicles
Cytosol Expressed in all parathyroid gland: 22.8 -MXD3 bHLHc13, MAD3 ENSG00000213347 MAX dimerization protein 3 5 177301461-177312757 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA070111 Approved Nucleus
Nucleoli Tissue enhanced 0 bone marrow: 24.3 skin: 12.6 -GSTM2 GST4 ENSG00000213366 Glutathione S-transferase mu 2 (muscle) 1 109668022-109709551 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB040547, HPA055972, HPA055973 Approved Supported Nucleoplasm
Vesicles
Cytosol Expressed in all ovary: 200.5 -COG8 DOR1, FLJ22315 ENSG00000213380 Component of oligomeric golgi complex 8 16 69320140-69339667 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041406, HPA049429 Approved Supported Golgi apparatus Expressed in all testis: 39.6 -ARHGAP19 FLJ00194, MGC14258 ENSG00000213390 Rho GTPase activating protein 19 10 97222173-97292673 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035777, HPA043231 Uncertain Approved Vesicles
Plasma membrane Mixed testis: 34.1 -HAUS7 UCHL5IP, UIP1 ENSG00000213397 HAUS augmin-like complex, subunit 7 X 153447666-153495516 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003614 Approved Nucleoli
Plasma membrane
Centrosome
Cytosol Mixed skin: 64.0 -LCAT ENSG00000213398 Lecithin-cholesterol acyltransferase 16 67939750-67944131 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044767 Approved Nucleoplasm Expressed in all liver: 105.3 -MAGEA12 CT1.12, MAGE12 ENSG00000213401 Melanoma antigen family A12 X 152733779-152737669 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 17 testis: 4.9 cerebral cortex: 0.2 -PTPRCAP CD45-AP, LPAP ENSG00000213402 Protein tyrosine phosphatase, receptor type, C-associated protein 11 67435510-67438067 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043734 Supported Tissue enhanced 0 appendix: 66.5;lymph node: 92.8;spleen: 86.7 tonsil: 30.0 -PVRIG C7orf15, MGC2463 ENSG00000213413 Poliovirus receptor related immunoglobulin domain containing 7 100218241-100221490 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047497 Uncertain Approved Nucleoli
Endoplasmic reticulum Tissue enhanced 0 lymph node: 20.8;spleen: 11.3 appendix: 8.8 -KRTAP4-12 KAP4.12 ENSG00000213416 Keratin associated protein 4-12 17 41123091-41124167 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -KRTAP2-4 KAP2.4 ENSG00000213417 Keratin associated protein 2-4 17 41065116-41065879 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA059203 Supported Not detected epididymis: 0.0 -GPC2 cerebroglycan, DKFZp547M109, FLJ38962 ENSG00000213420 Glypican 2 7 100169606-100177372 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB025423, HPA053945 Uncertain Uncertain Nucleus
Nucleoli
Golgi apparatus Tissue enhanced 0 skin: 5.7;testis: 10.1 cerebral cortex: 3.4 -KRT222 KA21, KRT222P, MGC45562 ENSG00000213424 Keratin 222, type II 17 40654665-40665181 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043708, HPA054586, HPA069774 Uncertain Approved Vesicles
Lipid droplets Tissue enhanced 0 cerebral cortex: 10.0;epididymis: 3.1 gallbladder: 2.7 -SIPA1 SPA1 ENSG00000213445 Signal-induced proliferation-associated 1 11 65585395-65650930 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020833, HPA039867 Supported Approved Nucleus
Nucleoli
Golgi apparatus
Plasma membrane Tissue enhanced 0 spleen: 101.8 lymph node: 72.4 -ERV3-1 envR, ERV-R, ERV3, H-PLK, HERV-R ENSG00000213462 Endogenous retrovirus group 3, member 1 7 64990809-65006743 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA017209 Approved Vesicles Mixed adrenal gland: 40.0 -SYNJ2BP Arip2 ENSG00000213463 Synaptojanin 2 binding protein 14 70366496-70417061 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000866 Approved Supported Approved Mitochondria Mixed parathyroid gland: 40.3 -ARL2 ARFL2 ENSG00000213465 ADP-ribosylation factor-like 2 11 65014113-65022184 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044610 Supported Approved Nucleus
Nucleoli
Golgi apparatus
Focal adhesion sites
Cytosol Expressed in all fallopian tube: 112.7 -GBP7 FLJ38822, GBP4L ENSG00000213512 Guanylate binding protein 7 1 89131751-89176040 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA051245 Uncertain Tissue enriched 89 liver: 48.3 adrenal gland: 0.5 -RBMXL1 KAT3 ENSG00000213516 RNA binding motif protein, X-linked-like 1 1 88979456-88992960 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057707 Supported Approved Nucleoplasm Expressed in all parathyroid gland: 18.7 -SRA1 SRA, STRAA1 ENSG00000213523 Steroid receptor RNA activator 1 5 140537340-140558310 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044598, HPA050153 Approved Supported Nucleoplasm
Microtubules
Cytosol Mixed adrenal gland: 16.7 -TMEM110 MGC52022 ENSG00000213533 Transmembrane protein 110 3 52836219-52897596 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA051855 Uncertain Approved Cytosol Expressed in all fallopian tube: 20.8 -DNAJC9 JDD1, SB73 ENSG00000213551 DnaJ (Hsp40) homolog, subfamily C, member 9 10 73183362-73248862 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035215, HPA035216 Supported Supported Nucleoplasm
Plasma membrane Expressed in all bone marrow: 37.4 -C8orf82 MGC70857 ENSG00000213563 Chromosome 8 open reading frame 82 8 144525733-144529132 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034331 Uncertain Approved Nucleus Expressed in all prostate: 29.9 -CPLX3 CPX-III ENSG00000213578 Complexin 3 15 74826547-74831802 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Group enriched 8 prostate: 127.7;spleen: 75.8 cerebral cortex: 12.9 -VDAC1 MGC111064, PORIN ENSG00000213585 Voltage-dependent anion channel 1 5 133971915-134005133 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005885, HPA030780 Supported Approved Cytosol Expressed in all skeletal muscle: 363.8 -ZBTB9 MGC23166, ZNF919 ENSG00000213588 Zinc finger and BTB domain containing 9 6 33453970-33457548 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036767 Uncertain Mixed tonsil: 2.7 -TMX2 PDIA12, TXNDC14 ENSG00000213593 Thioredoxin-related transmembrane protein 2 11 57712600-57740973 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040282, HPA063763 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 129.2 -HEXA ENSG00000213614 Hexosaminidase A (alpha polypeptide) 15 72340919-72376476 Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA054583 Supported Expressed in all epididymis: 197.5 -NDUFS3 CI-30 ENSG00000213619 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 11 47565336-47584562 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004484 Approved Supported Nuclear bodies
Mitochondria Expressed in all skeletal muscle: 127.3 -LEPROT FLJ90360, OB-RGRP, OBRGRP, VPS55 ENSG00000213625 Leptin receptor overlapping transcript 1 65420587-65436007 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA069444 Approved Centrosome Expressed in all placenta: 79.7 -LBH ENSG00000213626 Limb bud and heart development 2 30231531-30323730 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034669 Approved Approved Vesicles Expressed in all lung: 197.5 -ADAT3 TAD3 ENSG00000213638 Adenosine deaminase, tRNA-specific 3 19 1905378-1913447 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058899 Uncertain Approved Nucleus Tissue enhanced 0 duodenum: 7.7 small intestine: 5.4 -PPP1CB PP-1B, PP1B, PP1beta ENSG00000213639 Protein phosphatase 1, catalytic subunit, beta isozyme 2 28751640-28802940 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022558, HPA065425, CAB069426 Supported Supported Nucleus
Plasma membrane
Cytosol Expressed in all esophagus: 274.9 -SULT1A4 ENSG00000213648 Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 16 29459889-29464976 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049500, HPA051051 Supported Tissue enhanced 0 duodenum: 178.1;small intestine: 133.7 colon: 39.3 -GPSM3 AGS4, C6orf9, G18, G18.1a, G18.1b, G18.2, NG1 ENSG00000213654 G-protein signaling modulator 3 6 32190766-32195523 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 25.7;lymph node: 27.9;spleen: 29.8 tonsil: 16.1 -LAT LAT1 ENSG00000213658 Linker for activation of T cells 16 28984826-28990783 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002223, HPA011157, CAB012978 Supported Tissue enhanced 0 lymph node: 76.5 appendix: 33.0 -NCKIPSD AF3P21, DIP1, ORF1, SPIN90, WASLBP, WISH ENSG00000213672 NCK interacting protein with SH3 domain 3 48673844-48686364 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019267, HPA050005 Validated Plasma membrane
Cytosol Tissue enriched 9 parathyroid gland: 300.2 cerebral cortex: 35.1 -ATF6B CREBL1, G13 ENSG00000213676 Activating transcription factor 6 beta 6 32098176-32128253 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046871 Uncertain Supported Nucleus
Nucleoli Expressed in all parathyroid gland: 55.8 -TREX1 AGS1, DRN3 ENSG00000213689 Three prime repair exonuclease 1 3 48465811-48467645 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035437 Supported Expressed in all spleen: 28.4 -S1PR3 EDG-3, EDG3 ENSG00000213694 Sphingosine-1-phosphate receptor 3 9 88991447-89005010 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed smooth muscle: 51.8 -SLC35F6 ANT2BP, C2orf18, FLJ20555, TANGO9 ENSG00000213699 Solute carrier family 35, member F6 2 26764284-26781231 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA034655 Approved Approved Nucleoplasm
Vesicles
Cytosol Expressed in all thyroid gland: 26.2 -FAM209B C20orf107, dJ1153D9.4 ENSG00000213714 Family with sequence similarity 209, member B 20 56533246-56536520 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042144 Supported Tissue enriched 22 testis: 111.9 bone marrow: 5.0 -CLIC1 NCC27, p64CLCP ENSG00000213719 Chloride intracellular channel 1 6 31730581-31739763 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB020825, CAB040557 Supported Supported Cytosol Expressed in all rectum: 71.3 -DDAH2 ENSG00000213722 Dimethylarginine dimethylaminohydrolase 2 6 31727038-31730617 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012509 Uncertain Uncertain Microtubule organizing center
Cytosol Mixed thyroid gland: 22.3 -RPS29 S29 ENSG00000213741 Ribosomal protein S29 14 49570984-49599164 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004107 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all breast: 3614.6 -UGT2B11 ENSG00000213759 UDP glucuronosyltransferase 2 family, polypeptide B11 4 69004618-69214731 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045108 Uncertain Tissue enriched 16 breast: 314.2 gallbladder: 19.0 -ATP6V1G2 ATP6G, ATP6G2, Em:AC004181.3, NG38, Vma10 ENSG00000213760 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 6 31544462-31548427 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB004616 Supported Tissue enriched 12 cerebral cortex: 16.8 lymph node: 1.4 -ZNF134 pHZ-15 ENSG00000213762 Zinc finger protein 134 19 57614233-57624723 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA009064 Supported Approved Nucleoplasm Expressed in all parathyroid gland: 25.2 -GTF2H4 P52, TFB2, TFIIH ENSG00000213780 General transcription factor IIH, polypeptide 4, 52kDa 6 30908184-30914106 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA074336 Supported Nuclear speckles Mixed appendix: 3.7 -DDX47 DKFZp564O176, FLJ30012, HQ0256, RRP3 ENSG00000213782 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 12 12813316-12829981 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014855 Approved Validated Nucleoli Expressed in all thyroid gland: 55.5 -ZNF845 ENSG00000213799 Zinc finger protein 845 19 53333749-53354869 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Mixed thyroid gland: 8.2 -KLRK1 CD314, D12S2489E, KLR, NKG2-D, NKG2D ENSG00000213809 Killer cell lectin-like receptor subfamily K, member 1 12 10372353-10391874 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021896, HPA068877 Supported Supported Plasma membrane Tissue enhanced 0 lymph node: 35.7;spleen: 53.6 tonsil: 16.7 -CEACAM18 ENSG00000213822 Carcinoembryonic antigen-related cell adhesion molecule 18 19 51478622-51490952 Predicted secreted proteins Evidence at protein level Evidence at protein level No evidence HPA059487 Uncertain Approved Midbody Group enriched 14 duodenum: 10.8;small intestine: 7.3 gallbladder: 0.6 -EMP2 XMP ENSG00000213853 Epithelial membrane protein 2 16 10528422-10580698 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014711 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 lung: 344.5 skin: 166.7 -KCTD11 C17orf36, KCASH1, REN ENSG00000213859 Potassium channel tetramerization domain containing 11 17 7351889-7354944 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052035 Approved Approved Nucleoplasm Mixed esophagus: 40.0 -C8orf44 FLJ11267 ENSG00000213865 Chromosome 8 open reading frame 44 8 66667615-66685564 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA043660, HPA054753 Uncertain Validated Nucleoplasm Mixed epididymis: 20.9 -UBD FAT10 ENSG00000213886 Ubiquitin D 6 29555515-29559925 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043710 Supported Nucleus
Nucleoli fibrillar center Tissue enhanced 0 lymph node: 96.1;tonsil: 96.3 appendix: 44.8 -PPM1N FLJ40125 ENSG00000213889 Protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) 19 45488777-45502510 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA043577 Supported Vesicles Tissue enriched 5 skeletal muscle: 69.9 spleen: 13.1 -CEACAM16 DFNA4B ENSG00000213892 Carcinoembryonic antigen-related cell adhesion molecule 16 19 44699151-44710714 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045075 Uncertain Not detected tonsil: 0.6 -SLC23A3 FLJ31168, SVCT3, Yspl1 ENSG00000213901 Solute carrier family 23, member 3 2 219161465-219170095 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level HPA019059 Approved Nucleus
Cell Junctions Tissue enhanced 0 kidney: 52.7;small intestine: 23.3 duodenum: 9.0 -LTB4R BLTR, CMKRL1, GPR16, LTB4R1, P2RY7, P2Y7 ENSG00000213903 Leukotriene B4 receptor 14 24311450-24318036 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA003873 Approved Tissue enhanced 0 skin: 165.5 esophagus: 42.8 -LTB4R2 BLT2, BLTR2, JULF2, NOP9 ENSG00000213906 Leukotriene B4 receptor 2 14 24305734-24312053 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB022689, HPA029680, HPA072921 Uncertain Supported Nucleoplasm
Plasma membrane Tissue enhanced 0 skin: 40.6 spleen: 11.2 -DNASE1 DNL1 ENSG00000213918 Deoxyribonuclease I 16 3611728-3680143 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010703 Approved Approved Vesicles Tissue enhanced 0 small intestine: 38.6 duodenum: 30.8 -MDP1 FN6Pase, MGC5987 ENSG00000213920 Magnesium-dependent phosphatase 1 14 24213937-24216070 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003064, HPA070338 Uncertain Approved Nucleoplasm Expressed in all thyroid gland: 20.2 -LEUTX ENSG00000213921 Leucine twenty homeobox 19 39776595-39786135 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA041498 Uncertain Approved Nucleus
Nucleoli Not detected adipose tissue: 0.0 -CSNK1E CKIE, CKIepsilon, HCKIE ENSG00000213923 Casein kinase 1, epsilon 22 38290691-38398522 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009626, HPA026288 Approved Approved Nucleus
Cytosol Expressed in all parathyroid gland: 173.6 -CCL27 ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine ENSG00000213927 Chemokine (C-C motif) ligand 27 9 34661880-34664048 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 16 skin: 502.8 breast: 31.9 -IRF9 ISGF3G ENSG00000213928 Interferon regulatory factor 9 14 24161053-24166565 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001862 Approved Supported Cytosol Expressed in all spleen: 96.0 -GALT ENSG00000213930 Galactose-1-phosphate uridylyltransferase 9 34638133-34651035 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004868, HPA005729 Supported Approved Cytosol Expressed in all liver: 25.8 -HBE1 HBE ENSG00000213931 Hemoglobin, epsilon 1 11 5268345-5505617 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043234 Approved Approved Vesicles Tissue enhanced 0 testis: 1.0 placenta: 0.9 -HBG1 HBG-T2 ENSG00000213934 Hemoglobin, gamma A 11 5248083-5249892 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043234 Approved Tissue enriched 213 placenta: 253.1 spleen: 1.1 -CLDN9 ENSG00000213937 Claudin 9 16 3012456-3014505 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA076613 Supported Vesicles
Cell Junctions Tissue enhanced 0 parathyroid gland: 3.1 bone marrow: 1.7 -ITGA1 CD49a, VLA1 ENSG00000213949 Integrin, alpha 1 5 52787896-52959210 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042555 Uncertain Approved Endoplasmic reticulum Mixed spleen: 78.9 -NUDT19 RP2 ENSG00000213965 Nudix (nucleoside diphosphate linked moiety X)-type motif 19 19 32691961-32713796 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042761 Uncertain Nucleus
Nucleoli
Cytosol Expressed in all prostate: 12.4 -ZNF726 ENSG00000213967 Zinc finger protein 726 19 23914876-23945159 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed breast: 7.3 -ZNF99 C19orf9, MGC24986 ENSG00000213973 Zinc finger protein 99 19 22752183-22784107 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 7 testis: 3.0 cerebral cortex: 0.4 -TAX1BP3 TIP-1 ENSG00000213977 Tax1 (human T-cell leukemia virus type I) binding protein 3 17 3662896-3668682 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046410, HPA063078 Approved Approved Nucleoli fibrillar center
Vesicles
Actin filaments Expressed in all cervix: 226.7 -AP1G2 G2AD ENSG00000213983 Adaptor-related protein complex 1, gamma 2 subunit 14 23559565-23568070 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004106 Approved Mixed parathyroid gland: 57.6 -ZNF90 HTF9 ENSG00000213988 Zinc finger protein 90 19 20077994-20127076 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA003227 Uncertain Approved Nucleus
Golgi apparatus Tissue enhanced 0 parathyroid gland: 8.5 thyroid gland: 3.6 -CARKD FLJ10769, LP3298 ENSG00000213995 Carbohydrate kinase domain containing 13 110615460-110639993 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA010551 Uncertain Expressed in all seminal vesicle: 27.0 -TM6SF2 Lpr4 ENSG00000213996 Transmembrane 6 superfamily member 2 19 19264364-19273391 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA066026 Uncertain Group enriched 5 duodenum: 79.1;small intestine: 78.4 liver: 14.6 -MEF2B RSRFR2 ENSG00000213999 Myocyte enhancer factor 2B 19 19145568-19170289 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004734 Supported Group enriched 9 appendix: 18.2;lymph node: 46.3;tonsil: 28.2 spleen: 3.3 -GANC ENSG00000214013 Glucosidase, alpha; neutral C 15 42273233-42356935 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA016949 Approved Approved Nucleoplasm
Actin filaments Expressed in all lung: 42.6 -TTLL3 DKFZP434B103, HOTTL ENSG00000214021 Tubulin tyrosine ligase-like family member 3 3 9808086-9855138 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051413 Approved Expressed in all testis: 53.2 -REPIN1 AP4, H_DJ0584D14.12, RIP60, Zfp464, ZNF464 ENSG00000214022 Replication initiator 1 7 150368189-150374044 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036022 Approved Validated Nucleus Expressed in all spleen: 49.2 -MRPL23 L23MRP, RPL23L ENSG00000214026 Mitochondrial ribosomal protein L23 11 1947278-1984522 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050406 Approved Supported Nucleoli fibrillar center
Mitochondria Expressed in all fallopian tube: 88.5 -ZNF891 ENSG00000214029 Zinc finger protein 891 12 133106817-133130473 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA040301 Uncertain Mixed testis: 2.2 -IFNA7 IFN-alphaJ, IFNA-J ENSG00000214042 Interferon, alpha 7 9 21201469-21202205 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected adipose tissue: 0.0 -SMIM7 C19orf42, MGC2747 ENSG00000214046 Small integral membrane protein 7 19 16630751-16660442 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043127 Uncertain Approved Golgi apparatus Expressed in all epididymis: 55.0 -FBXO16 FBX16 ENSG00000214050 F-box protein 16 8 28348287-28490318 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053955, HPA058676 Uncertain Approved Nucleoplasm
Vesicles
Plasma membrane
Cytosol Tissue enhanced 0 epididymis: 26.9 thyroid gland: 12.6 -TSPAN4 NAG-2, TETRASPAN, TM4SF7, TSPAN-4 ENSG00000214063 Tetraspanin 4 11 842808-867116 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all spleen: 107.3 -CPNE1 CPN1 ENSG00000214078 Copine I 20 35626031-35664956 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047259, HPA072634 Approved Supported Nucleoplasm
Nuclear membrane Expressed in all smooth muscle: 102.7 -ARL16 ENSG00000214087 ADP-ribosylation factor-like 16 17 81681174-81683924 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043711 Uncertain Expressed in all cerebral cortex: 37.9 -SMCO1 C3orf43, DKFZp313B0440, FLJ41923 ENSG00000214097 Single-pass membrane protein with coiled-coil domains 1 3 196506877-196515366 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA061937 Uncertain Group enriched 15 heart muscle: 23.7;skeletal muscle: 51.1 esophagus: 2.5 -WEE2 FLJ16107 ENSG00000214102 WEE1 homolog 2 (S. pombe) 7 141708353-141731271 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA027418 Uncertain Supported Nucleoplasm
Cytosol Mixed epididymis: 1.8 -MAGEB1 CT3.1, DAM10, MAGE-Xp, MAGEL1, MGC9322 ENSG00000214107 Melanoma antigen family B1 X 30243730-30252038 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001193, HPA002820 Supported Tissue enriched 46 testis: 29.1 epididymis: 0.6 -LYRM4 C6orf149, CGI-203, ISD11 ENSG00000214113 LYR motif containing 4 6 5102593-5260939 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030362 Approved Supported Nuclear bodies Expressed in all ovary: 30.0 -MYCBP AMY-1 ENSG00000214114 MYC binding protein 1 38862964-38874105 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041188, HPA078331 Supported Supported Mitochondria
Cytosol Expressed in all fallopian tube: 38.6 -TMEM213 ENSG00000214128 Transmembrane protein 213 7 138797952-138838101 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA054059 Approved Group enriched 9 kidney: 80.1;salivary gland: 22.8 breast: 5.8 -PRCD RP36 ENSG00000214140 Progressive rod-cone degeneration 17 76527586-76553578 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed parathyroid gland: 3.0 -ALG3 CDGS4, D16Ertd36e, Not56, NOT56L ENSG00000214160 ALG3, alpha-1,3- mannosyltransferase 3 184242301-184249548 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045103 Approved Expressed in all parathyroid gland: 32.7 -ZNF788 FLJ46419 ENSG00000214189 Zinc finger family member 788 19 12092263-12137235 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed testis: 5.6 -SH3D21 C1orf113, FLJ22938 ENSG00000214193 SH3 domain containing 21 1 36306387-36324886 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042212, HPA042456, HPA066168 Approved Approved Nucleus
Plasma membrane Tissue enhanced 0 small intestine: 28.3 skin: 17.8 -C19orf38 HIDE1 ENSG00000214212 Chromosome 19 open reading frame 38 19 10836575-10869790 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012150, HPA055027 Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 bone marrow: 62.9 spleen: 17.8 -C12orf74 ENSG00000214215 Chromosome 12 open reading frame 74 12 92702843-92708549 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 1.9 urinary bladder: 0.9 -IQCJ ENSG00000214216 IQ motif containing J 3 158962928-159266307 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052835 Uncertain Not detected testis: 0.8 -C17orf67 ENSG00000214226 Chromosome 17 open reading frame 67 17 56791913-56838773 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043479 Uncertain Approved Mixed spleen: 3.8 -FIS1 CGI-135, Fis1, H_NH0132A01.6, TTC11 ENSG00000214253 Fission, mitochondrial 1 7 101239458-101252316 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017430 Approved Validated Mitochondria Expressed in all thyroid gland: 269.1 -ANG RAA1, RNASE5 ENSG00000214274 Angiogenin, ribonuclease, RNase A family, 5 14 20684177-20698971 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 27 liver: 1557.7 prostate: 58.5 -NPS ENSG00000214285 Neuropeptide S 10 127549369-127552639 Predicted secreted proteins No evidence No evidence No evidence CAB020139 Uncertain Not detected adipose tissue: 0.0 -COLCA2 C11orf93, CASC13 ENSG00000214290 Colorectal cancer associated 2 11 111298546-111308735 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed epididymis: 35.0 -SPDYE3 ENSG00000214300 Speedy/RINGO cell cycle regulator family member E3 7 100307702-100322196 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044799, HPA051750 Uncertain Tissue enriched 11 testis: 2.3 skin: 0.2 -MBLAC1 MGC49416 ENSG00000214309 Metallo-beta-lactamase domain containing 1 7 100126694-100128498 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA071574 Uncertain Mixed cerebral cortex: 3.9 -FOXI3 ENSG00000214336 Forkhead box I3 2 88446787-88452656 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 8 placenta: 7.3 testis: 0.8 -SOGA3 C6orf174, dJ403A15.3 ENSG00000214338 SOGA family member 3 6 127472794-127519191 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA035388, HPA035389 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 cerebral cortex: 10.2 endometrium: 2.1 -NEURL1B DKFZP761M1511, Neur2 ENSG00000214357 Neuralized E3 ubiquitin protein ligase 1B 5 172641266-172691540 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA037612 Approved Supported Vesicles Mixed seminal vesicle: 44.6 -EFCAB9 ENSG00000214360 EF-hand calcium binding domain 9 5 172194172-172203452 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 97 testis: 15.8 gallbladder: 0.1 -HAUS3 C4orf15, dgt3, IT1, MGC4701 ENSG00000214367 HAUS augmin-like complex, subunit 3 4 2227464-2242164 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040649, HPA048190 Approved Approved Microtubules
Mitochondria Expressed in all bone marrow: 31.9 -VSTM5 C11orf90, LOC387804 ENSG00000214376 V-set and transmembrane domain containing 5 11 93818232-93850531 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA029525 Uncertain Uncertain Endoplasmic reticulum Tissue enhanced 0 placenta: 6.5 cerebral cortex: 2.8 -LCNL1 FLJ45224 ENSG00000214402 Lipocalin-like 1 9 136981904-136986410 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA060268 Uncertain Not detected seminal vesicle: 0.7 -BBIP1 bA348N5.3, BBIP10, BBS18, NCRNA00081 ENSG00000214413 BBSome interacting protein 1 10 110898730-110919274 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055206 Uncertain Expressed in all testis: 179.2 -TRIM77 TRIM77P ENSG00000214414 Tripartite motif containing 77 11 89710299-89717872 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA039896 Uncertain Not detected epididymis: 0.0 -GNAT3 GDCA, gustducin ENSG00000214415 Guanine nucleotide binding protein, alpha transducing 3 7 80458671-80512020 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 duodenum: 2.0;small intestine: 1.4 testis: 0.5 -AS3MT CYT19 ENSG00000214435 Arsenite methyltransferase 10 102869516-102901899 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017856, HPA027708 Approved Group enriched 6 adrenal gland: 252.7;parathyroid gland: 117.7 liver: 30.5 -FAM187A ENSG00000214447 Family with sequence similarity 187, member A 17 44899712-44905390 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA022794, HPA043131 Approved Approved Cytosol Tissue enhanced 0 fallopian tube: 24.3;testis: 17.2 thyroid gland: 5.3 -PLIN5 LSDA5, LSDP5, MLDP, OXPAT ENSG00000214456 Perilipin 5 19 4522531-4535224 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adipose tissue: 34.5;ovary: 42.4 salivary gland: 26.0 -SEC14L6 ENSG00000214491 SEC14-like lipid binding 6 22 30522799-30546682 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA067695 Approved Nucleoplasm Tissue enhanced 0 epididymis: 26.0;parathyroid gland: 45.5 lung: 18.0 -SPINK13 HBVDNAPTP1, HESPINTOR, LiESP6, MGC149260, SPINK5L3 ENSG00000214510 Serine peptidase inhibitor, Kazal type 13 (putative) 5 148268180-148286254 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA036456 Uncertain Approved Nucleus
Plasma membrane Tissue enriched 8 epididymis: 304.8 seminal vesicle: 36.9 -HIGD1C Gm921 ENSG00000214511 HIG1 hypoxia inducible domain family, member 1C 12 50953922-50970506 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 testis: 3.0 parathyroid gland: 2.5 -NOTO ENSG00000214513 Notochord homeobox 2 73202258-73212513 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA034660 Uncertain Not detected skin: 0.4 -PPME1 PME-1 ENSG00000214517 Protein phosphatase methylesterase 1 11 74171099-74254703 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004541, HPA043900, HPA064396 Uncertain Supported Nucleus Expressed in all parathyroid gland: 153.8 -KRTAP2-2 KAP2.2 ENSG00000214518 Keratin associated protein 2-2 17 41054498-41055230 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA059203 Supported Not detected adipose tissue: 0.0 -STARD10 CGI-52, NY-CO-28, PCTP2, SDCCAG28 ENSG00000214530 StAR-related lipid transfer (START) domain containing 10 11 72754729-72794168 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026661 Uncertain Expressed in all rectum: 209.4 -NUTM2D FAM22D ENSG00000214562 NUT family member 2D 10 87357668-87370695 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA064635 Uncertain Nuclear bodies Expressed in all cerebral cortex: 7.1 -CPEB1 CPEB, FLJ13203 ENSG00000214575 Cytoplasmic polyadenylation element binding protein 1 15 82543201-82648861 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040396 Approved Nucleoplasm
Vesicles Tissue enhanced 0 testis: 61.1 cerebral cortex: 22.4 -EML6 FLJ42562 ENSG00000214595 Echinoderm microtubule associated protein like 6 2 54723499-54972025 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062808, HPA068759 Uncertain Approved Vesicles
Mitochondria Tissue enhanced 0 lymph node: 7.6;tonsil: 8.7 appendix: 4.6 -DEFB113 DEFB-13 ENSG00000214642 Defensin, beta 113 6 49968677-49969625 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 1059 epididymis: 106.6 testis: 0.1 -DEFB133 ENSG00000214643 Defensin, beta 133 6 49946101-49949444 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 1098 epididymis: 339.8 testis: 0.3 -ZNF727 ZNF727P ENSG00000214652 Zinc finger protein 727 7 64045443-64078549 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level No evidence HPA051027, HPA061215 Uncertain Uncertain Nucleoplasm Mixed thyroid gland: 5.8 -ZSWIM8 4832404P21Rik, KIAA0913 ENSG00000214655 Zinc finger, SWIM-type containing 8 10 73785582-73801797 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041244 Approved Approved Plasma membrane
Cytosol Expressed in all parathyroid gland: 62.8 -IQCF5 ENSG00000214681 IQ motif containing F5 3 51873721-51875584 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 721 testis: 72.0 adipose tissue: 0.0 -IQCF6 ENSG00000214686 IQ motif containing F6 3 51778561-51779187 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 59 testis: 17.7 epididymis: 0.3 -C10orf105 FLJ00245 ENSG00000214688 Chromosome 10 open reading frame 105 10 71711701-71737824 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 2.3;spleen: 3.3 testis: 1.4 -ARHGEF33 ENSG00000214694 Rho guanine nucleotide exchange factor (GEF) 33 2 38889880-38975449 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA034661, HPA041051 Supported Supported Vesicles Tissue enhanced 0 testis: 10.7 ovary: 4.3 -C12orf71 LOC728858 ENSG00000214700 Chromosome 12 open reading frame 71 12 27081058-27082514 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA058728 Uncertain Tissue enhanced 0 testis: 5.0 skin: 1.0 -IFRD2 IFNRP, SKMc15, SM15 ENSG00000214706 Interferon-related developmental regulator 2 3 50287732-50292918 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068560 Approved Nucleoplasm Expressed in all thyroid gland: 28.6 -CAPN14 ENSG00000214711 Calpain 14 2 31173056-31233858 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 25 esophagus: 88.6 tonsil: 3.4 -ZBED1 ALTE, DREF, hDREF, KIAA0785, TRAMP ENSG00000214717 Zinc finger, BED-type containing 1 X 2486414-2500967 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077591 Approved Nucleoplasm
Nuclear membrane
Centrosome Expressed in all cervix: 24.5 -RP1-139D8.6 ENSG00000214732 6 42155426-42163439 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 361 testis: 67.6 cervix: 0.1 -TOMM6 OBTP ENSG00000214736 Translocase of outer mitochondrial membrane 6 homolog (yeast) 6 41787662-41789898 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004801 Approved Supported Mitochondria Expressed in all epididymis: 316.2 -HNRNPUL2 DKFZp762N1910, HNRPUL2 ENSG00000214753 Heterogeneous nuclear ribonucleoprotein U-like 2 11 62712630-62727349 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041632, HPA056696, HPA067699 Supported Validated Nucleoplasm Expressed in all cerebral cortex: 59.4 -METTL12 U99HG ENSG00000214756 Methyltransferase like 12 11 62665309-62668496 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA038115, HPA038533 Uncertain Not detected duodenum: 0.9 -MS4A18 ENSG00000214782 Membrane-spanning 4-domains, subfamily A, member 18 11 60729304-60744212 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045121 Approved Tissue enhanced 0 breast: 10.3;duodenum: 24.5 small intestine: 4.1 -MS4A4E ENSG00000214787 Membrane-spanning 4-domains, subfamily A, member 4E 11 60201253-60243088 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA040075 Uncertain Mixed adipose tissue: 5.8 -FER1L6 C8ORFK23 ENSG00000214814 Fer-1-like family member 6 8 123851987-124120061 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA054117 Uncertain Group enriched 5 rectum: 12.6;stomach: 44.3 small intestine: 5.4 -CDRT15L2 ENSG00000214819 CMT1A duplicated region transcript 15-like 2 17 20579724-20580911 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 11 testis: 13.2 epididymis: 1.1 -MTCP1 P13MTCP1, p8MTCP1 ENSG00000214827 Mature T-cell proliferation 1 X 155061622-155147937 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA032040 Approved Nucleoplasm
Plasma membrane Mixed testis: 8.7 -RAD51AP2 FLJ17540 ENSG00000214842 RAD51 associated protein 2 2 17510584-17518439 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 39 testis: 16.8 cerebral cortex: 0.4 -EVPLL ENSG00000214860 Envoplakin-like 17 18377662-18389647 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045728 Uncertain Approved Nucleoplasm
Nuclear bodies Tissue enhanced 0 esophagus: 3.5;skin: 6.1;testis: 4.1 lung: 1.8 -DCDC2C ENSG00000214866 Doublecortin domain containing 2C 2 3703592-3847408 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA045848 Uncertain Tissue enriched 30 testis: 8.1 fallopian tube: 0.2 -SMTNL1 CHASM ENSG00000214872 Smoothelin-like 1 11 57542641-57550274 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 26 skeletal muscle: 240.9 esophagus: 9.4 -TRIM64C ENSG00000214891 Tripartite motif containing 64C 11 49053714-49059112 Predicted intracellular proteins No evidence No evidence HPA045370 Uncertain Not detected adipose tissue: 0.0 -U82695.5 ENSG00000214897 X 153395640-153401420 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Group enriched 36 epididymis: 5.7;ovary: 4.7;testis: 10.9 fallopian tube: 0.2 -SPATA31D1 FAM75D1, FLJ46321 ENSG00000214929 SPATA31 subfamily D, member 1 9 81988772-81995256 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047897 Uncertain Tissue enriched 95 testis: 9.5 epididymis: 0.0 -NPIPA8 LCR16a9 ENSG00000214940 Nuclear pore complex interacting protein family, member A8 16 18317942-18336736 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA053611 Approved Approved Nucleoplasm Mixed cerebral cortex: 22.1 -ZSWIM7 SWS1 ENSG00000214941 Zinc finger, SWIM-type containing 7 17 15976560-15999717 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA054681 Uncertain Uncertain Cytosol Mixed cerebral cortex: 11.9 -GPR33 ENSG00000214943 G protein-coupled receptor 33 (gene/pseudogene) 14 31482964-31487945 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected spleen: 0.4 -ARHGEF28 p190RhoGEF, RGNEF, RIP2 ENSG00000214944 Rho guanine nucleotide exchange factor (GEF) 28 5 73626158-73941993 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037602 Approved Approved Plasma membrane
Microtubules
Cytosol Mixed kidney: 33.5 -TBC1D26 MGC51025 ENSG00000214946 TBC1 domain family, member 26 17 15732247-15749192 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 11 testis: 3.9 lung: 0.3 -LRRC69 ENSG00000214954 Leucine rich repeat containing 69 8 91101832-91219236 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046337 Uncertain Approved Plasma membrane Tissue enhanced 0 testis: 5.2 skin: 2.0 -ISPD hCG_1745121, IspD, Nip ENSG00000214960 Isoprenoid synthase domain containing 7 16087527-16421322 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043810, HPA053554 Approved Approved Nucleus
Nucleoli fibrillar center Mixed cerebral cortex: 3.5 -NPIPA7 ENSG00000214967 Nuclear pore complex interacting protein family, member A7 16 16379055-16393954 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA053611 Approved Approved Nucleoplasm Expressed in all parathyroid gland: 48.7 -GSG1L2 ENSG00000214978 GSG1-like 2 17 9802386-9822071 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA059428 Uncertain Group enriched 14 cerebral cortex: 1.5;testis: 1.1 epididymis: 0.0 -ACSM4 ENSG00000215009 Acyl-CoA synthetase medium-chain family member 4 12 7304284-7328724 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA049895 Uncertain Tissue enhanced 0 ovary: 2.5;testis: 2.6 spleen: 1.2 -C22orf29 FLJ21125 ENSG00000215012 Chromosome 22 open reading frame 29 22 19846138-19854896 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA000721, HPA001419 Uncertain Mixed skin: 15.9 -COL28A1 ENSG00000215018 Collagen, type XXVIII, alpha 1 7 7356203-7535853 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA060468 Uncertain Tissue enhanced 0 epididymis: 17.9 salivary gland: 7.9 -PHB2 Bap37, BCAP37, p22, REA ENSG00000215021 Prohibitin 2 12 6965327-6970825 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB014889, CAB026335, HPA039874 Supported Validated Mitochondria Expressed in all ovary: 268.5 -TCP11X2 ENSG00000215029 T-complex 11 family, X-linked 2 X 102374628-102471812 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA048311 Supported Tissue enhanced 0 testis: 1.4 fallopian tube: 0.9 -NEURL4 KIAA1787 ENSG00000215041 Neuralized E3 ubiquitin protein ligase 4 17 7315628-7329393 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043678, HPA055314 Uncertain Expressed in all cerebral cortex: 19.0 -GRID2IP ENSG00000215045 Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 7 6497462-6551436 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA045381 Uncertain Mixed parathyroid gland: 1.4 -CXorf49B ENSG00000215113 Chromosome X open reading frame 49B X 71763424-71767204 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 51 testis: 5.0 epididymis: 0.0 -UBXN2B p37 ENSG00000215114 UBX domain protein 2B 8 58411264-58451501 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045278 Uncertain Approved Nucleoplasm Expressed in all parathyroid gland: 26.5 -CXorf49 ENSG00000215115 Chromosome X open reading frame 49 X 71714371-71718151 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 51 testis: 5.0 epididymis: 0.0 -CBWD7 ENSG00000215126 COBW domain containing 7 9 41131306-41199261 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA042759, HPA042813 Approved Approved Plasma membrane Tissue enhanced 0 adrenal gland: 4.9 breast: 2.8 -C16orf90 LOC646174 ENSG00000215131 Chromosome 16 open reading frame 90 16 3493484-3495480 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 215 testis: 21.4 epididymis: 0.0 -NLRP2P NALP2P, NOD24 ENSG00000215174 NLR family, pyrin domain containing 2 pseudogene X 57677067-57680260 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -MUC5AC MUC5 ENSG00000215182 Mucin 5AC, oligomeric mucus/gel-forming 11 1157953-1201138 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002774, CAB009395, HPA040456, HPA040615 Supported Uncertain Vesicles Tissue enriched 63 stomach: 365.1 cervix: 5.8 -MSMP PC-3, PSMP ENSG00000215183 Microseminoprotein, prostate associated 9 35752990-35756613 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055174 Uncertain Supported Vesicles
Cytosol Tissue enhanced 0 placenta: 1.8 breast: 0.3 -GOLGA6B ENSG00000215186 Golgin A6 family, member B 15 72654738-72666394 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA044978, HPA050087 Supported Group enriched 14 liver: 1.9;testis: 5.2 cerebral cortex: 0.2 -FAM166B ENSG00000215187 Family with sequence similarity 166, member B 9 35561831-35563899 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045540 Uncertain Group enriched 13 adrenal gland: 371.3;fallopian tube: 157.1;skeletal muscle: 82.6 epididymis: 15.9 -PEX26 FLJ20695 ENSG00000215193 Peroxisomal biogenesis factor 26 22 18077920-18131138 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB070429 Approved Expressed in all small intestine: 34.8 -GRXCR1 DFNB25, PPP1R88 ENSG00000215203 Glutaredoxin, cysteine rich 1 4 42893267-43030658 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040824 Uncertain Tissue enriched 8 seminal vesicle: 6.2 testis: 0.7 -C5orf49 LOC134121 ENSG00000215217 Chromosome 5 open reading frame 49 5 7830378-7851490 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043759 Uncertain Group enriched 10 fallopian tube: 118.9;testis: 30.8 lung: 7.8 -UBE2QL1 FLJ25076 ENSG00000215218 Ubiquitin-conjugating enzyme E2Q family-like 1 5 6448623-6494909 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA057414 Supported Nucleus
Plasma membrane Tissue enhanced 0 cerebral cortex: 42.0 seminal vesicle: 10.3 -FASTKD5 FLJ13149 ENSG00000215251 FAST kinase domains 5 20 3146519-3159897 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043833 Approved Expressed in all bone marrow: 22.9 -GOLGA8B ENSG00000215252 Golgin A8 family, member B 15 34525207-34588503 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051808 Approved Golgi apparatus
Cytosol Tissue enhanced 0 thyroid gland: 47.6 testis: 23.5 -KCNU1 KCa5.1, Kcnma3, KCNMC1, Slo3 ENSG00000215262 Potassium channel, subfamily U, member 1 8 36784324-36936128 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 24 testis: 13.4 adipose tissue: 0.5 -GAGE12G ENSG00000215269 G antigen 12G X 49570434-49577754 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enriched 12 testis: 124.2 stomach: 10.2 -HOMEZ KIAA1443 ENSG00000215271 Homeobox and leucine zipper encoding 14 23272422-23299447 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA036316, HPA036317 Approved Supported Nucleus
Nucleoli Expressed in all testis: 41.5 -GAGE10 ENSG00000215274 G antigen 10 X 49303669-49319844 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enhanced 0 ovary: 1.1;testis: 1.5 fallopian tube: 0.7 -RNF212B C14orf164 ENSG00000215277 Ring finger protein 212B 14 23185316-23273477 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053574 Uncertain Group enriched 17 kidney: 26.6;testis: 10.2 epididymis: 1.0 -DDX3X DBX, DDX14, DDX3, HLP2 ENSG00000215301 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked X 41333348-41364472 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001648, HPA005631, HPA059585 Supported Approved Approved Nucleus
Cytosol Expressed in all parathyroid gland: 270.3 -VPS16 ENSG00000215305 Vacuolar protein sorting 16 homolog (S. cerevisiae) 20 2840703-2866732 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043229, HPA048661 Approved Expressed in all parathyroid gland: 29.0 -ZNF705D ENSG00000215343 Zinc finger protein 705D 8 12104389-12115516 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 epididymis: 4.5 testis: 0.7 -ZNF705B ENSG00000215356 Zinc finger protein 705B 8 7926337-7952413 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 19 testis: 1.8 adipose tissue: 0.0 -ZNF705G ENSG00000215372 Zinc finger protein 705G 8 7355517-7385558 Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected testis: 0.9 -MYL5 ENSG00000215375 Myosin, light chain 5, regulatory 4 673580-682033 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA037381, HPA039262 Uncertain Approved Nucleus
Nucleoli Expressed in all parathyroid gland: 30.3 -SCRT2 ZNF898B ENSG00000215397 Scratch family zinc finger 2 20 661596-676179 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA067697 Approved Nucleoplasm Not detected cerebral cortex: 0.7 -ZNF407 FLJ13839, FLJ20307, KIAA1703 ENSG00000215421 Zinc finger protein 407 18 74597870-75065671 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028255, HPA041673 Uncertain Approved Nucleoplasm
Plasma membrane Mixed parathyroid gland: 8.8 -NPEPL1 bA261P9.2, FLJ11583 ENSG00000215440 Aminopeptidase-like 1 20 58689131-58719238 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004986, CAB017025, HPA036356 Approved Approved Nucleoplasm Expressed in all spleen: 25.2 -KRTAP10-4 KAP10.4, KRTAP18-4, KRTAP18.4 ENSG00000215454 Keratin associated protein 10-4 21 44573729-44575371 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected fallopian tube: 0.1 -KRTAP10-1 KAP10.1, KAP18.1, KRTAP18-1 ENSG00000215455 Keratin associated protein 10-1 21 44538981-44540195 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -RPL17-C18orf32 ENSG00000215472 RPL17-C18orf32 readthrough 18 49481681-49492479 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043724, HPA046385 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all cerebral cortex: 66.4 -SKOR2 CORL2, Fussel-18, FUSSEL18 ENSG00000215474 SKI family transcriptional corepressor 2 18 47212089-47249183 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046206 Uncertain Not detected testis: 0.5 -SIAH3 FLJ39203 ENSG00000215475 Siah E3 ubiquitin protein ligase family member 3 13 45777243-45851736 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA060576 Uncertain Tissue enhanced 0 fallopian tube: 5.0 cerebral cortex: 1.4 -EFCAB8 ENSG00000215529 EF-hand calcium binding domain 8 20 32858923-32961609 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence CAB034246, HPA042751 Uncertain Tissue enriched 6 testis: 2.8 thyroid gland: 0.4 -DEFB116 DEFB-16 ENSG00000215545 Defensin, beta 116 20 31303212-31308585 Predicted secreted proteins No evidence No evidence No evidence HPA047430 Uncertain Not detected epididymis: 0.5 -DEFB115 DEFB-15 ENSG00000215547 Defensin, beta 115 20 31257664-31259632 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA053160 Uncertain Tissue enriched 55 epididymis: 5.4 adipose tissue: 0.0 -GAB4 ENSG00000215568 GRB2-associated binding protein family, member 4 22 16961936-17008222 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044621 Uncertain Tissue enriched 38 testis: 3.7 epididymis: 0.0 -C20orf202 ENSG00000215595 Chromosome 20 open reading frame 202 20 1203454-1208274 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042786 Uncertain Tissue enhanced 0 placenta: 4.8 lung: 1.9 -HMX1 H6, NKX5-3 ENSG00000215612 H6 family homeobox 1 4 8846076-8871817 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 1.1 testis: 0.9 -GCGR GGR ENSG00000215644 Glucagon receptor 17 81804132-81814013 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071228 Approved Golgi apparatus Group enriched 7 adrenal gland: 6.6;kidney: 8.5;liver: 20.9;parathyroid gland: 9.4 skin: 1.6 -RSC1A1 RS1 ENSG00000215695 Regulatory solute carrier protein, family 1, member 1 1 15659869-15661722 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA027813, HPA028676 Approved Supported Nucleoplasm
Cell Junctions Mixed smooth muscle: 5.2 -CELA2B ELA2B, RP11-265F14.2 ENSG00000215704 Chymotrypsin-like elastase family, member 2B 1 15465909-15491400 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 258 pancreas: 4260.7 ovary: 16.4 -TMEM242 BM033, C6orf35 ENSG00000215712 Transmembrane protein 242 6 157289386-157323601 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA025764 Approved Expressed in all cerebral cortex: 17.0 -TMEM167B AD-020, C1orf119, FLJ90710 ENSG00000215717 Transmembrane protein 167B 1 109089803-109096934 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Expressed in all thyroid gland: 49.3 -FAM72D ENSG00000215784 Family with sequence similarity 72, member D 1 145096000-145112696 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043271, HPA067321 Uncertain Approved Vesicles
Plasma membrane
Cytosol Tissue enhanced 0 lymph node: 5.7 tonsil: 4.2 -TNFRSF25 APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR ENSG00000215788 Tumor necrosis factor receptor superfamily, member 25 1 6461151-6466195 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA077620 Approved Cell Junctions Tissue enhanced 0 skin: 29.7 spleen: 12.3 -SLC35E2 KIAA0447 ENSG00000215790 Solute carrier family 35, member E2 1 1724838-1745992 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062711 Uncertain Uncertain Nucleus Mixed thyroid gland: 7.5 -TSTD1 KAT ENSG00000215845 Thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 1 161037631-161038990 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006518, HPA006655 Approved Approved Cytosol
Cytoplasmic bodies Expressed in all thyroid gland: 146.2 -RPTN FLJ39117 ENSG00000215853 Repetin 1 152153595-152159228 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030483, HPA030485 Supported Group enriched 35 skin: 35.2;tonsil: 49.2 esophagus: 1.2 -CYB5RL LOC606495 ENSG00000215883 Cytochrome b5 reductase-like 1 54172336-54200036 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042671, HPA060463 Approved Validated Nucleoplasm Mixed thyroid gland: 3.3 -LACTBL1 ENSG00000215906 Lactamase, beta-like 1 1 22953043-22965338 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.3 -C1orf167 DKFZp434E1410, RP11-56N19.2 ENSG00000215910 Chromosome 1 open reading frame 167 1 11761787-11789585 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039114 Uncertain Tissue enriched 33 testis: 14.7 lung: 0.4 -TTC34 ENSG00000215912 Tetratricopeptide repeat domain 34 1 2635976-2789755 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA066832 Uncertain Group enriched 5 fallopian tube: 2.1;testis: 3.7;thyroid gland: 1.1 spleen: 0.4 -ATAD3C FLJ34599 ENSG00000215915 ATPase family, AAA domain containing 3C 1 1449689-1470158 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA065305 Approved Mitochondria Mixed thyroid gland: 3.4 -IFI30 GILT, IFI-30, IP-30, IP30, MGC32056 ENSG00000216490 Interferon, gamma-inducible protein 30 19 18173162-18178117 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA026650 Approved Supported Vesicles
Cytosol Expressed in all appendix: 848.1 -IGSF23 ENSG00000216588 Immunoglobulin superfamily, member 23 19 44613630-44636781 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051811, HPA054591 Uncertain Approved Nucleus
Cell Junctions Group enriched 7 duodenum: 15.6;liver: 13.1;small intestine: 17.8 testis: 2.3 -GAGE12E ENSG00000216649 G antigen 12E X 49551333-49558649 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enriched 25 testis: 4.3 stomach: 0.1 -CCDC7 BIOT2, C10orf68, FLJ13031, FLJ32762 ENSG00000216937 Coiled-coil domain containing 7 10 32446140-32574564 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA075536 Approved Nucleoli
Cytosol Tissue enriched 38 testis: 131.0 thyroid gland: 3.4 -FNIP1 KIAA1961 ENSG00000217128 Folliculin interacting protein 1 5 131641714-131797063 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA068099, HPA071213 Approved Expressed in all testis: 28.4 -SP9 ZNF990 ENSG00000217236 Sp9 transcription factor 2 174334946-174338492 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA062616 Uncertain Approved Mitochondria Tissue enhanced 0 fallopian tube: 1.4 skin: 0.9 -SYCE3 C22orf41 ENSG00000217442 Synaptonemal complex central element protein 3 22 50551112-50562905 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA047813 Approved Nucleus
Nucleoli
Golgi apparatus Tissue enriched 38 testis: 116.2 thyroid gland: 3.0 -CKLF C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1 ENSG00000217555 Chemokine-like factor 16 66552563-66566251 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA062779 Approved Vesicles Expressed in all testis: 91.2 -PAM16 Magmas, Tim16, TIMM16 ENSG00000217930 Presequence translocase-associated motor 16 homolog (S. cerevisiae) 16 4331549-4355607 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062721 Approved Nucleoplasm
Microtubules
Mitochondria Expressed in all testis: 15.2 -TENM3 KIAA1455, ODZ3, Ten-M3 ENSG00000218336 Teneurin transmembrane protein 3 4 182143987-182803024 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA047043 Approved Approved Nucleoplasm Tissue enhanced 0 placenta: 18.7 parathyroid gland: 13.8 -CEBPZOS CEBPZ-AS1 ENSG00000218739 CEBPZ opposite strand 2 37196488-37216193 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053866 Uncertain Approved Nucleoplasm Expressed in all epididymis: 48.4 -TDRD15 ENSG00000218819 Tudor domain containing 15 2 21123917-21143272 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051770, HPA054675 Uncertain Tissue enriched 77 testis: 9.9 liver: 0.1 -PAPOLB PAPT ENSG00000218823 Poly(A) polymerase beta (testis specific) 7 4857733-4861994 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 536 testis: 53.6 adipose tissue: 0.0 -ZNF579 FLJ35453 ENSG00000218891 Zinc finger protein 579 19 55576770-55580845 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062812 Approved Approved Nucleus Expressed in all gallbladder: 13.0 -CELA3B CBPP, ELA3B ENSG00000219073 Chymotrypsin-like elastase family, member 3B 1 21977021-21998642 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028086, HPA045650 Supported Approved Cytosol Tissue enriched 291 pancreas: 10565.5 ovary: 36.3 -RNASEK MGC71993 ENSG00000219200 Ribonuclease, RNase K 17 7012417-7014532 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044708 Uncertain Expressed in all adrenal gland: 470.3 -TEX40 C11orf20, DKFZP566E164 ENSG00000219435 Testis expressed 40 11 64300446-64304770 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA052822 Approved Nucleoplasm Tissue enriched 108 testis: 388.8 cerebral cortex: 3.6 -FAM19A5 TAFA-5 ENSG00000219438 Family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 22 48489460-48850912 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB025629 Approved Tissue enhanced 0 cerebral cortex: 50.1 cervix: 12.9 -NBPF1 FLJ20719, KIAA1693 ENSG00000219481 Neuroblastoma breakpoint family, member 1 1 16562319-16613562 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Mixed testis: 21.8 -PPP1R3G ENSG00000219607 Protein phosphatase 1, regulatory subunit 3G 6 5084581-5089487 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056393 Uncertain Mixed spleen: 3.7 -FAM228B ENSG00000219626 Family with sequence similarity 228, member B 2 24076526-24169640 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA052598, HPA063357 Uncertain Approved Golgi apparatus Mixed testis: 36.5 -LINGO3 LERN2, LRRN6B ENSG00000220008 Leucine rich repeat and Ig domain containing 3 19 2289784-2292024 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA043781, HPA055932, HPA059558 Uncertain Approved Mitochondria Tissue enhanced 0 spleen: 3.9 appendix: 1.7 -ZGLP1 GATAD3, GLP-1, GLP1 ENSG00000220201 Zinc finger, GATA-like protein 1 19 10304803-10309880 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049855 Uncertain Approved Nucleus
Vesicles Mixed testis: 3.1 -VAMP2 SYB2, VAMP-2 ENSG00000220205 Vesicle-associated membrane protein 2 (synaptobrevin 2) 17 8159149-8163546 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB078785 Supported Expressed in all cerebral cortex: 485.0 -OR6B1 OR7-3 ENSG00000221813 Olfactory receptor, family 6, subfamily B, member 1 7 144003929-144004983 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA053164 Uncertain Not detected testis: 0.3 -EBF2 COE2, FLJ11500 ENSG00000221818 Early B-cell factor 2 8 25841730-26045397 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 adipose tissue: 20.6 heart muscle: 6.7 -C6orf226 LOC441150 ENSG00000221821 Chromosome 6 open reading frame 226 6 42890265-42890816 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045350 Approved Approved Nuclear speckles Expressed in all adrenal gland: 13.4 -PPP3R1 CALNB1, CNB, CNB1 ENSG00000221823 Protein phosphatase 3, regulatory subunit B, alpha 2 68178857-68256237 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005610, HPA047157 Approved Approved Plasma membrane
Cytosol Expressed in all cerebral cortex: 198.1 -PSG3 ENSG00000221826 Pregnancy specific beta-1-glycoprotein 3 19 42721638-42740569 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046327 Approved Tissue enriched 161 placenta: 188.4 testis: 1.1 -FANCG FAG, XRCC9 ENSG00000221829 Fanconi anemia, complementation group G 9 35073835-35080016 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008105, HPA045335 Approved Supported Nucleoli
Plasma membrane
Cytosol Mixed fallopian tube: 8.5 -OR2A5 OR2A26, OR2A8, OR7-138, OR7-141 ENSG00000221836 Olfactory receptor, family 2, subfamily A, member 5 7 144050368-144051380 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected seminal vesicle: 0.1 -KRTAP10-9 KAP10.9, KAP18.9, KRTAP18-9 ENSG00000221837 Keratin associated protein 10-9 21 44627123-44628293 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -AP4M1 MU-4, MU-ARP2, SPG50 ENSG00000221838 Adaptor-related protein complex 4, mu 1 subunit 7 100101549-100110345 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA066774 Approved Expressed in all testis: 28.9 -OR4A5 ENSG00000221840 Olfactory receptor, family 4, subfamily A, member 5 11 54706885-54707832 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -C2orf16 DKFZp434G118 ENSG00000221843 Chromosome 2 open reading frame 16 2 27576522-27582720 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA052136, HPA056962 Uncertain Uncertain Nuclear bodies Tissue enriched 15 testis: 15.3 thyroid gland: 1.0 -KRTAP1-5 KAP1.5 ENSG00000221852 Keratin associated protein 1-5 17 41026026-41027202 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 13 cervix, uterine: 2.1 prostate: 0.1 -TAS2R41 T2R59 ENSG00000221855 Taste receptor, type 2, member 41 7 143477873-143478796 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA057063 Uncertain Not detected adipose tissue: 0.0 -OR2A12 OR2A12P ENSG00000221858 Olfactory receptor, family 2, subfamily A, member 12 7 144095048-144096093 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -KRTAP10-10 KAP10.10, KAP18.10, KRTAP18-10 ENSG00000221859 Keratin associated protein 10-10 21 44637356-44638455 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -KRTAP12-2 KAP12.2, KRTAP12.2 ENSG00000221864 Keratin associated protein 12-2 21 44666189-44666927 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected epididymis: 0.1 -PLXNA4 DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B ENSG00000221866 Plexin A4 7 132123332-132648688 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029919, HPA052141 Supported Tissue enhanced 0 adipose tissue: 15.2;cervix, uterine: 12.4 cerebral cortex: 10.5 -MAGEA3 CT1.3, HIP8, HYPD, MAGE3, MGC14613 ENSG00000221867 Melanoma antigen family A3 X 152698752-152702347 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 28 testis: 12.8 placenta: 0.4 -CEBPD C/EBP-delta, CELF, CRP3, NF-IL6-beta ENSG00000221869 CCAAT/enhancer binding protein (C/EBP), delta 8 47736909-47739086 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067581 Supported Nucleoplasm Expressed in all adipose tissue: 71.2 -TMEM257 CXorf1 ENSG00000221870 Transmembrane protein 257 X 145827410-145829850 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 10 cerebral cortex: 4.2 seminal vesicle: 0.4 -ZNF816-ZNF321P ZNF816-ZNF321 ENSG00000221874 ZNF816-ZNF321P readthrough 19 52928475-52962823 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA051271 Uncertain Uncertain Nucleoplasm Tissue enhanced 0 prostate: 2.3 rectum: 1.5 -PSG7 ENSG00000221878 Pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 19 42906822-43082671 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level HPA046327 Approved Tissue enhanced 0 placenta: 7.1;skin: 1.4 smooth muscle: 0.9 -KRTAP1-3 KAP1.3 ENSG00000221880 Keratin associated protein 1-3 17 41033884-41034855 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -OR3A2 OLFRA04, OR17-228, OR228 ENSG00000221882 Olfactory receptor, family 3, subfamily A, member 2 17 3277899-3278974 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 6 testis: 5.3 cerebral cortex: 0.8 -ARIH2OS C3orf71 ENSG00000221883 Ariadne homolog 2 opposite strand 3 48917788-48919385 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed testis: 4.2 -ZBED8 Buster3, C5orf54 ENSG00000221886 Zinc finger, BED-type containing 8 5 160393148-160400097 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045445, HPA055817 Approved Validated Nucleoplasm Mixed ovary: 13.2 -HMSD ACC-6, ACC6, C18orf53 ENSG00000221887 Histocompatibility (minor) serpin domain containing 18 63949301-63981774 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed lymph node: 1.9 -OR1C1 HSTPCR27, TPCR27 ENSG00000221888 Olfactory receptor, family 1, subfamily C, member 1 1 247757462-247758406 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 40 testis: 4.0 adipose tissue: 0.0 -NPTXR ENSG00000221890 Neuronal pentraxin receptor 22 38818452-38843982 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA001079 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enriched 14 cerebral cortex: 177.0 fallopian tube: 13.0 -POM121L12 DKFZp564N2472 ENSG00000221900 POM121 transmembrane nucleoporin-like 12 7 53035642-53036924 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027836 Uncertain Tissue enriched 88 testis: 8.8 epididymis: 0.0 -FAM200A C7orf38, DKFZp727G131, FLJ36794 ENSG00000221909 Family with sequence similarity 200, member A 7 99546308-99558536 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017855 Uncertain Mixed testis: 15.2 -OR2F2 OR7-1 ENSG00000221910 Olfactory receptor, family 2, subfamily F, member 2 7 143935166-143936279 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -PPP2R2A B55A, PR52A, PR55A ENSG00000221914 Protein phosphatase 2, regulatory subunit B, alpha 8 26291491-26372680 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042122, HPA042770, HPA059497 Approved Approved Cytosol Expressed in all placenta: 72.3 -C19orf73 FLJ10490 ENSG00000221916 Chromosome 19 open reading frame 73 19 49118397-49119140 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062719 Uncertain Approved Nucleus
Cytosol Mixed duodenum: 2.3 -ZNF880 ENSG00000221923 Zinc finger protein 880 19 52369917-52385795 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA077316 Approved Intermediate filaments Expressed in all thyroid gland: 31.2 -TRIM16 EBBP ENSG00000221926 Tripartite motif containing 16 17 15627960-15684311 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023623, HPA066431 Uncertain Supported Plasma membrane
Cytosol Expressed in all esophagus: 118.3 -OR6X1 ENSG00000221931 Olfactory receptor, family 6, subfamily X, member 1 11 123753488-123754545 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.1 -HEPN1 ENSG00000221932 Hepatocellular carcinoma, down-regulated 1 11 124919244-124920677 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA043768, HPA063054 Uncertain Approved Golgi apparatus Tissue enriched 6 cerebral cortex: 79.7 adipose tissue: 12.9 -OR2A25 OR2A25P, OR2A27 ENSG00000221933 Olfactory receptor, family 2, subfamily A, member 25 7 144074182-144075195 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA058272 Uncertain Not detected adipose tissue: 0.0 -TAS2R40 GPR60 ENSG00000221937 Taste receptor, type 2, member 40 7 143222037-143223079 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 appendix: 1.0 spleen: 0.3 -OR2A14 OR2A14P, OR2A6, OST182 ENSG00000221938 Olfactory receptor, family 2, subfamily A, member 14 7 144109583-144130069 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -TIGD1 EEYORE ENSG00000221944 Tigger transposable element derived 1 2 232547968-232550592 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041717 Approved Supported Nucleus
Nucleoli
Nuclear bodies Expressed in all testis: 18.1 -FXYD7 ENSG00000221946 FXYD domain containing ion transport regulator 7 19 35143250-35154301 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026916 Approved Tissue enriched 34 cerebral cortex: 106.1 lymph node: 3.1 -XKR9 ENSG00000221947 XK, Kell blood group complex subunit-related family, member 9 8 70669365-70790371 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044430 Uncertain Approved Mitochondria Tissue enhanced 0 testis: 14.1 small intestine: 6.2 -OR4C12 ENSG00000221954 Olfactory receptor, family 4, subfamily C, member 12 11 49981473-49982535 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -SLC12A8 CCC9 ENSG00000221955 Solute carrier family 12, member 8 3 125082636-125212864 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031123 Uncertain Supported Nucleoplasm Tissue enhanced 0 thyroid gland: 39.4 gallbladder: 16.3 -PRR21 ENSG00000221961 Proline rich 21 2 240041813-240042982 Predicted intracellular proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -TMEM14EP TMEM14E ENSG00000221962 Transmembrane protein 14E, pseudogene 3 152340527-152340904 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA014550 Uncertain Tissue enhanced 0 skin: 1.0 bone marrow: 0.9 -APOL6 APOL-VI, APOLVI ENSG00000221963 Apolipoprotein L, 6 22 35648395-35668409 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB028574, HPA029165, HPA029167 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Mixed spleen: 25.5 -FADS3 CYB5RP, LLCDL3 ENSG00000221968 Fatty acid desaturase 3 11 61873519-61892051 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA045224 Approved Expressed in all adipose tissue: 98.7 -OR2A1 ENSG00000221970 Olfactory receptor, family 2, subfamily A, member 1 7 144318125-144319057 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA058272 Uncertain Tissue enhanced 0 thyroid gland: 3.2 ovary: 1.4 -C3orf36 FLJ22173 ENSG00000221972 Chromosome 3 open reading frame 36 3 133928145-133929812 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046432 Uncertain Tissue enriched 7 seminal vesicle: 11.7 parathyroid gland: 1.5 -OR4E2 ENSG00000221977 Olfactory receptor, family 4, subfamily E, member 2 14 21665083-21666024 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.1 -CCNL2 ania-6b, CCNM, CCNS, HLA-ISO, PCEE, SB138 ENSG00000221978 Cyclin L2 1 1385711-1399328 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053137 Supported Supported Nucleoplasm Expressed in all endometrium: 68.4 -UBA52 CEP52, HUBCEP52, L40, MGC126879, MGC126881, MGC57125, RPL40 ENSG00000221983 Ubiquitin A-52 residue ribosomal protein fusion product 1 19 18571730-18577550 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041344, HPA049132, HPA056624 Supported Approved Nucleoplasm
Endoplasmic reticulum
Plasma membrane
Cytosol Expressed in all ovary: 1909.1 -MYBPHL ENSG00000221986 Myosin binding protein H-like 1 109292365-109307041 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 19 heart muscle: 68.4 fallopian tube: 3.6 -PPT2 ENSG00000221988 Palmitoyl-protein thioesterase 2 6 32153441-32163680 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed skin: 8.7 -OR2A2 OR2A17P, OR2A2P, OST008 ENSG00000221989 Olfactory receptor, family 2, subfamily A, member 2 7 144109514-144110564 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -ZNF630 BC037316, dJ54B20.2, FLJ20573, MGC138344 ENSG00000221994 Zinc finger protein 630 X 47983356-48071658 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA001053, HPA068130 Approved Approved Nucleus
Cytosol Mixed parathyroid gland: 7.4 -TIAF1 ENSG00000221995 TGFB1-induced anti-apoptotic factor 1 17 29073521-29078857 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051129 Uncertain Mixed skin: 4.8 -BTBD19 ENSG00000222009 BTB (POZ) domain containing 19 1 44808482-44815585 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042633, HPA076404 Uncertain Approved Cytosol Mixed endometrium: 4.4 -FAM185A MGC35361 ENSG00000222011 Family with sequence similarity 185, member A 7 102748971-102809225 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA020470, HPA029883 Uncertain Validated Cytosol Mixed parathyroid gland: 4.3 -RAB6C WTH3 ENSG00000222014 RAB6C, member RAS oncogene family 2 129979664-129982738 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA059131 Uncertain Uncertain Golgi apparatus Tissue enhanced 0 parathyroid gland: 15.1 cerebral cortex: 3.6 -C21orf140 ENSG00000222018 Chromosome 21 open reading frame 140 21 34400317-34401072 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045123 Uncertain Mixed testis: 10.5 -PSMB11 beta5t ENSG00000222028 Proteasome (prosome, macropain) subunit, beta type, 11 14 23042167-23044276 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected testis: 0.2 -POTEM ACT, P704P, POTE14beta ENSG00000222036 POTE ankyrin domain family, member M 14 18967434-18999012 Predicted intracellular proteins No evidence No evidence No evidence HPA042822 Uncertain Not detected adipose tissue: 0.0 -POTEJ POTE2beta ENSG00000222038 POTE ankyrin domain family, member J 2 130611481-130658091 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA041264, HPA041271, HPA042822, HPA043260 Uncertain Tissue enhanced 0 testis: 1.0 prostate: 0.6 -DCDC2B ENSG00000222046 Doublecortin domain containing 2B 1 32209094-32216196 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045832 Uncertain Tissue enriched 16 fallopian tube: 43.9 lung: 2.7 -C10orf55 bA417O11.3 ENSG00000222047 Chromosome 10 open reading frame 55 10 73909969-73922777 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045739 Uncertain Approved Nucleus Not detected kidney: 0.3 -TRIM49D1 TRIM49D, TRIM49D1P, TRIM49DP ENSG00000223417 Tripartite motif containing 49D1 11 89911111-89921767 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected prostate: 0.1 -USP17L2 DUB3 ENSG00000223443 Ubiquitin specific peptidase 17-like family member 2 8 12137168-12139077 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045642 Uncertain Tissue enriched 12 epididymis: 1.2 adipose tissue: 0.0 -EXOSC6 EAP4, hMtr3p, MTR3, Mtr3p, p11 ENSG00000223496 Exosome component 6 16 70246778-70251930 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 22.9 -VPS52 ARE1, SACM2L ENSG00000223501 Vacuolar protein sorting 52 homolog (S. cerevisiae) 6 33250272-33272047 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042667, HPA048128 Approved Mixed thyroid gland: 8.6 -CDRT15 ENSG00000223510 CMT1A duplicated region transcript 15 17 14235673-14236862 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055952 Uncertain Approved Cell Junctions Tissue enhanced 0 testis: 11.6 skin: 4.0 -ZNF844 FLJ14959 ENSG00000223547 Zinc finger protein 844 19 12064699-12081565 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA046982 Uncertain Mixed thyroid gland: 20.2 -USP17L15 ENSG00000223569 Ubiquitin specific peptidase 17-like family member 15 4 9234385-9365080 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -CKMT1A CKMT1 ENSG00000223572 Creatine kinase, mitochondrial 1A 15 43692886-43699222 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043491 Uncertain Mixed rectum: 75.0 -CENPVP1 CENPVL1, PRR6L1 ENSG00000223591 Centromere protein V pseudogene 1 X 51710512-51712131 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 3.0 cerebral cortex: 0.8 -EBLN1 ENSG00000223601 Endogenous Bornavirus-like nucleoprotein 1 10 22208814-22210021 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 43 testis: 4.2 adipose tissue: 0.0 -HBD ENSG00000223609 Hemoglobin, delta 11 5232678-5235370 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037087, HPA043234 Supported Tissue enriched 65 bone marrow: 1224.5 placenta: 18.8 -ZNF735 ZNF735P ENSG00000223614 Zinc finger protein 735 7 64207090-64220508 Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence No evidence Evidence at protein level Not detected testis: 0.2 -RFPL4A RFPL4, RNF210 ENSG00000223638 Ret finger protein-like 4A 19 55759014-55763175 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046368 Uncertain Approved Centrosome
Cytosol Tissue enhanced 0 epididymis: 2.5;testis: 2.5 liver: 1.2 -C1GALT1C1L ENSG00000223658 C1GALT1-specific chaperone 1 like 2 43675151-43676322 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 testis: 11.8 epididymis: 8.0 -CERS1 LAG1, LASS1, UOG1 ENSG00000223802 Ceramide synthase 1 19 18868545-18896727 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045724 Approved Approved Endoplasmic reticulum Group enriched 13 cerebral cortex: 136.6;testis: 28.0 skeletal muscle: 6.5 -HLA-DPB1 HLA-DP1B ENSG00000223865 Major histocompatibility complex, class II, DP beta 1 6 33075926-33087201 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA011078, HPA058509 Approved Approved Nucleus
Cell Junctions Expressed in all spleen: 174.2 -C1QTNF5 CTRP5, DKFZp586B0621, LORD ENSG00000223953 C1q and tumor necrosis factor related protein 5 11 119338939-119340940 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025607, HPA038604 Uncertain Mixed gallbladder: 71.8 -CPTP GLTPD1, MGC10334 ENSG00000224051 Ceramide-1-phosphate transfer protein 1 1324756-1328897 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA056832 Approved Approved Cytosol Expressed in all testis: 47.0 -CT47A10 CT47.10 ENSG00000224089 Cancer/testis antigen family 47, member A10 X 120938701-120942023 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 21 testis: 2.0 adipose tissue: 0.0 -CENPVP3 ENSG00000224109 Centromere protein V pseudogene 3 X 51618055-51618918 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected cerebral cortex: 0.7 -PRR29 C17orf72, DKFZp761M2312, FLJ11724 ENSG00000224383 Proline rich 29 17 63998351-64004304 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051264 Approved Nucleoli Tissue enriched 12 fallopian tube: 91.7 testis: 7.9 -C4B C4B1, C4B3, C4F, CH, CO4, CPAMD3 ENSG00000224389 Complement component 4B (Chido blood group) 6 32014762-32035418 Blood group antigen proteins, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046356, HPA048287, HPA050103 Approved Tissue enhanced 0 adrenal gland: 59.8;liver: 65.6 kidney: 18.4 -ADM5 AM5, C19orf76 ENSG00000224420 Adrenomedullin 5 (putative) 19 49688664-49690575 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed skin: 2.6 -ATXN1L BOAT1 ENSG00000224470 Ataxin 1-like 16 71845991-71885268 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062596, HPA062789 Validated Nucleus Expressed in all parathyroid gland: 35.9 -SMIM13 C6orf228 ENSG00000224531 Small integral membrane protein 13 6 11094033-11138733 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA065706 Approved Approved Nucleus
Nuclear membrane
Golgi apparatus Tissue enhanced 0 cerebral cortex: 47.3 placenta: 18.7 -GPX5 ENSG00000224586 Glutathione peroxidase 5 6 28525925-28534952 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 30 epididymis: 11.9 seminal vesicle: 0.3 -GAGE12J GAGE11 ENSG00000224659 G antigen 12J X 49322057-49329384 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enriched 47 testis: 42.7 epididymis: 0.9 -ZNF812 ENSG00000224689 Zinc finger protein 812 19 9689924-9700817 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level HPA055332 Uncertain Tissue enriched 8 esophagus: 24.0 urinary bladder: 3.1 -NPIPA3 ENSG00000224712 Nuclear pore complex interacting protein family, member A3 16 14708944-14765448 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA053611 Approved Approved Nucleoplasm Mixed parathyroid gland: 4.3 -C17orf89 ENSG00000224877 Chromosome 17 open reading frame 89 17 81239239-81241281 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA057732 Uncertain Approved Mitochondria Expressed in all cerebral cortex: 63.8 -GAGE12H ENSG00000224902 G antigen 12H X 49579983-49587301 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA043232 Supported Approved Golgi apparatus
Plasma membrane
Cytosol Tissue enriched 404 testis: 40.3 epididymis: 0.0 -APOC4-APOC2 ENSG00000224916 APOC4-APOC2 readthrough (NMD candidate) 19 44942238-44949565 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA055877 Supported Tissue enriched 61 liver: 4036.7 small intestine: 66.2 -PRRT4 ENSG00000224940 Proline-rich transmembrane protein 4 7 128350325-128361685 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046373, HPA052681 Uncertain Approved Nucleoplasm
Peroxisomes
Plasma membrane Group enriched 12 adipose tissue: 15.7;bone marrow: 41.2 cerebral cortex: 2.3 -TMEM233 IFITMD2 ENSG00000224982 Transmembrane protein 233 12 119593459-119643066 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA047506 Uncertain Group enriched 5 cerebral cortex: 16.3;skeletal muscle: 11.5;thyroid gland: 21.4 parathyroid gland: 3.1 -LL0XNC01-16G2.1 ENSG00000225110 X 153317681-153321822 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 4.0 adrenal gland: 0.9 -PLEKHM1 KIAA0356 ENSG00000225190 Pleckstrin homology domain containing, family M (with RUN domain) member 1 17 45435900-45490749 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025018, HPA039473 Approved Supported Nucleoli
Vesicles Mixed esophagus: 11.9 -USP17L3 USP17B, USP17F ENSG00000225327 Ubiquitin specific peptidase 17-like family member 3 8 7976393-7977985 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -CT62 ENSG00000225362 Cancer/testis antigen 62 15 71110244-71115494 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045306 Uncertain Tissue enriched 16 testis: 49.8 breast: 3.2 -MKRN2OS C3orf83, MKRN2-AS1 ENSG00000225526 MKRN2 opposite strand 3 12514934-12561059 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA065586, HPA065753 Uncertain Approved Golgi apparatus Mixed epididymis: 10.7 -C2CD4D FAM148D ENSG00000225556 C2 calcium-dependent domain containing 4D 1 151837819-151840557 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed skin: 1.9 -ZNF469 KIAA1858 ENSG00000225614 Zinc finger protein 469 16 88427471-88440757 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA069784 Approved Vesicles Mixed cervix: 2.3 -FAM195B ENSG00000225663 Family with sequence similarity 195, member B 17 81822361-81833302 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045542 Approved Approved Cytosol Expressed in all cerebral cortex: 107.4 -SLC26A6 DKFZp586E1422 ENSG00000225697 Solute carrier family 26 (anion exchanger), member 6 3 48625723-48635493 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA048363 Approved Uncertain Cytosol Expressed in all rectum: 24.3 -OR6V1 GPR138 ENSG00000225781 Olfactory receptor, family 6, subfamily V, member 1 7 143052320-143053347 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -CTD-2313N18.7 ENSG00000225805 11 71878453-71884561 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enriched 7 epididymis: 63.6 parathyroid gland: 8.6 -FAM229A ENSG00000225828 Family with sequence similarity 229, member A 1 32361270-32364278 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 7 testis: 15.7 spleen: 2.2 -ERCC6 ARMD5, CKN2, CSB, RAD26 ENSG00000225830 Excision repair cross-complementation group 6 10 49455368-49539538 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066830 Supported Nucleus Mixed testis: 10.0 -LINC00694 ENSG00000225873 Long intergenic non-protein coding RNA 694 3 44421130-44424007 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 7 testis: 26.5 spleen: 3.8 -FRG2B ENSG00000225899 FSHD region gene 2 family, member B 10 133623895-133626795 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039264, HPA047769 Uncertain Tissue enriched 6 parathyroid gland: 1.3 placenta: 0.2 -NOL7 C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1 ENSG00000225921 Nucleolar protein 7, 27kDa 6 13615327-13632739 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029185, HPA049693 Supported Validated Nucleus
Nucleoli
Mitochondria Expressed in all parathyroid gland: 91.5 -CTAGE4 cTAGE-4, FLJ43692 ENSG00000225932 CTAGE family, member 4 7 144183466-144186053 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA000387, HPA000922 Uncertain Mixed thyroid gland: 16.7 -C5orf67 ENSG00000225940 Chromosome 5 open reading frame 67 5 56511567-56606232 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Group enriched 8 epididymis: 19.4;kidney: 9.3 thyroid gland: 1.8 -NTF4 GLC1O, NT-4/5, NTF5 ENSG00000225950 Neurotrophin 4 19 49055793-49065076 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049376 Approved Golgi apparatus Tissue enhanced 0 skin: 36.6 seminal vesicle: 10.3 -ELFN1 PPP1R28 ENSG00000225968 Extracellular leucine-rich repeat and fibronectin type III domain containing 1 7 1688119-1747954 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 cerebral cortex: 3.6;liver: 3.8 endometrium: 1.7 -PIGBOS1 ENSG00000225973 PIGB opposite strand 1 15 55317184-55319161 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Expressed in all thyroid gland: 26.2 -CT47A6 CT47.6 ENSG00000226023 Cancer/testis antigen family 47, member A6 X 120953282-120961487 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA042483 Approved Not detected testis: 0.5 -FTCDNL1 FONG ENSG00000226124 Formiminotransferase cyclodeaminase N-terminal like 2 199760544-199851173 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA065748 Uncertain Vesicles Mixed thyroid gland: 11.9 -TEX22 ENSG00000226174 Testis expressed 22 14 105398579-105450106 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA065576 Uncertain Tissue enhanced 0 testis: 2.1 cerebral cortex: 0.8 -OR52I2 ENSG00000226288 Olfactory receptor, family 52, subfamily I, member 2 11 4586791-4587905 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA049343 Uncertain Not detected epididymis: 0.2 -CROCC2 ENSG00000226321 Ciliary rootlet coiled-coil, rootletin family member 2 2 240906330-240993311 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA048678 Uncertain Group enriched 5 fallopian tube: 8.6;spleen: 3.3 lung: 1.1 -DCAF8L1 WDR42B ENSG00000226372 DDB1 and CUL4 associated factor 8-like 1 X 27977993-27981355 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043787 Approved Tissue enriched 57 testis: 5.6 adipose tissue: 0.0 -USP17L7 ENSG00000226430 Ubiquitin specific peptidase 17-like family member 7 8 12132417-12134444 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected epididymis: 0.8 -TMEM185B FAM11B, FLJ20979 ENSG00000226479 Transmembrane protein 185B 2 120221278-120223408 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048295, HPA071744 Uncertain Approved Endoplasmic reticulum Expressed in all parathyroid gland: 61.4 -CT47A9 CT47.9 ENSG00000226600 Cancer/testis antigen family 47, member A9 X 120943561-120946883 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 21 testis: 2.0 adipose tissue: 0.0 -KIF4B ENSG00000226650 Kinesin family member 4B 5 155013755-155018132 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA034745, HPA034746, HPA061583 Uncertain Validated Nucleoplasm Tissue enriched 63 testis: 6.2 epididymis: 0.0 -CT47A12 CT47.12 ENSG00000226685 Cancer/testis antigen family 47, member A12 X 120930250-120932301 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 24 testis: 2.3 adipose tissue: 0.0 -HSBP1L1 FLJ10967, MGC189743 ENSG00000226742 Heat shock factor binding protein 1-like 1 18 79964561-79970822 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA048273 Approved Approved Nucleoplasm Expressed in all colon: 12.3 -TAS2R46 T2R54 ENSG00000226761 Taste receptor, type 2, member 46 12 11061365-11062294 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -SRRM5 ENSG00000226763 Serine/arginine repetitive matrix 5 19 43596617-43614497 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047399 Uncertain Tissue enriched 31 testis: 40.4 lymph node: 1.3 -PGAM4 dJ1000K24.1, PGAM-B, PGAM1, PGAM3 ENSG00000226784 Phosphoglycerate mutase family member 4 X 77968874-77969638 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA042528, HPA049237, HPA060483 Uncertain Approved Nucleoplasm Not detected appendix: 0.5 -ERVMER34-1 ENSG00000226887 Endogenous retrovirus group MER34, member 1 4 52722618-52751640 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA011423, HPA024053 Uncertain Approved Nucleus
Cytosol Group enriched 8 parathyroid gland: 47.3;placenta: 15.5 kidney: 3.7 -CT47A11 CT47.11 ENSG00000226929 Cancer/testis antigen family 47, member A11 X 120933840-120937158 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 36 testis: 3.5 adipose tissue: 0.0 -RBMY1J ENSG00000226941 RNA binding motif protein, Y-linked, family 1, member J Y 22308823-22417881 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA001534, HPA053147 Supported Tissue enriched 49 testis: 8.7 lung: 0.1 -LTA LT, TNFB, TNFSF1 ENSG00000226979 Lymphotoxin alpha 6 31572054-31574324 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA007729 Uncertain Tissue enhanced 0 lymph node: 1.6;spleen: 1.0 tonsil: 0.7 -WDR46 BING4, C6orf11, UTP7 ENSG00000227057 WD repeat domain 46 6 33279108-33289527 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043004 Uncertain Tissue enhanced 0 epididymis: 16.1 tonsil: 10.3 -ANHX ENSG00000227059 Anomalous homeobox 12 133218312-133236095 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 76 testis: 7.5 epididymis: 0.0 -ZNF717 X17, ZNF838 ENSG00000227124 Zinc finger protein 717 3 75709643-75785583 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA044549 Uncertain Approved Nucleoplasm
Nuclear bodies
Plasma membrane Expressed in all epididymis: 29.1 -USP17L5 ENSG00000227140 Ubiquitin specific peptidase 17-like family member 5 4 9339403-9340995 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -PRR20D ENSG00000227151 Proline rich 20D 13 57160632-57163653 Predicted intracellular proteins No evidence No evidence No evidence HPA059485 Uncertain Not detected testis: 0.1 -SPANXB1 CT11.2, SPANXB2, SPANXF1, SPANXF2 ENSG00000227234 SPANX family, member B1 X 141002591-141003706 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046423 Uncertain Approved Nucleoplasm
Vesicles Tissue enriched 369 testis: 42.3 kidney: 0.1 -KLLN killin ENSG00000227268 Killin, p53-regulated DNA replication inhibitor 10 87859161-87863437 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA074502 Supported Nucleus Not detected epididymis: 0.6 -PARG ENSG00000227345 Poly (ADP-ribose) glycohydrolase 10 49818279-49970203 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021819, HPA053007 Approved Validated Nucleus
Vesicles Mixed parathyroid gland: 16.6 -AKR1B15 ENSG00000227471 Aldo-keto reductase family 1, member B15 7 134549136-134579875 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA020280, HPA073633 Uncertain Supported Plasma membrane
Cytosol Tissue enriched 12 breast: 176.5 duodenum: 14.1 -GAGE12D ENSG00000227488 G antigen 12D X 49541767-49549094 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enriched 472 testis: 47.1 epididymis: 0.0 -SCAMP4 FLJ33847 ENSG00000227500 Secretory carrier membrane protein 4 19 1905214-1926013 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA043284 Approved Approved Golgi apparatus
Vesicles
Lipid droplets
Plasma membrane Expressed in all fallopian tube: 58.6 -LTB p33, TNFC, TNFSF3 ENSG00000227507 Lymphotoxin beta (TNF superfamily, member 3) 6 31580525-31582522 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048884 Approved Approved Centrosome Group enriched 8 appendix: 19.4;lymph node: 22.5;spleen: 26.4;tonsil: 10.6 bone marrow: 2.6 -USP17L12 ENSG00000227551 Ubiquitin specific peptidase 17-like family member 12 4 9220152-9221744 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -RD3L TDRD9-AS1, TDRD9AS1 ENSG00000227729 Retinal degeneration 3-like 14 103940426-103942308 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA067971 Uncertain Tissue enriched 91 heart muscle: 21.0 liver: 0.2 -C1orf234 ENSG00000227868 Chromosome 1 open reading frame 234 1 23010834-23015850 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 109 testis: 97.5 epididymis: 0.8 -MRLN LINC00948, M1, MLN, MUSER1 ENSG00000227877 Myoregulin 10 59736692-59756041 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 skeletal muscle: 65.4 kidney: 14.4 -POLR2J2 RPB11b1 ENSG00000228049 Polymerase (RNA) II (DNA directed) polypeptide J2 7 102665368-102671629 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042997, HPA044010, HPA046970 Approved Approved Nucleoplasm Mixed appendix: 7.2 -BOD1L2 BOD1P, FAM44C, MGC33608 ENSG00000228075 Biorientation of chromosomes in cell division 1-like 2 18 57147062-57150300 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA036293 Uncertain Tissue enriched 4237 testis: 423.7 adipose tissue: 0.0 -IFNA14 IFN-alphaH, LEIF2H ENSG00000228083 Interferon, alpha 14 9 21239002-21239991 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected kidney: 0.1 -OR2M3 OR2M3P, OR2M6, OST003 ENSG00000228198 Olfactory receptor, family 2, subfamily M, member 3 1 248203068-248204006 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -MT-ATP8 A6L, ATP8, MTATP8 ENSG00000228253 Mitochondrially encoded ATP synthase 8 MT 8366-8572 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all skeletal muscle: 66430.7 -ORM2 AGP-B, AGP-B', AGP2 ENSG00000228278 Orosomucoid 2 9 114329869-114333252 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046438, HPA047725, HPA057726 Approved Approved Golgi apparatus
Vesicles Tissue enriched 75 liver: 3754.6 prostate: 49.7 -C19orf24 FLJ20640 ENSG00000228300 Chromosome 19 open reading frame 24 19 1275438-1279249 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043279, HPA047026 Uncertain Approved Nuclear speckles
Golgi apparatus Expressed in all appendix: 37.5 -OST4 ENSG00000228474 Oligosaccharyltransferase complex subunit 4 (non-catalytic) 2 27070472-27071773 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cervix: 341.9 -CT47A7 CT47.7 ENSG00000228517 Cancer/testis antigen family 47, member A7 X 120953288-120956600 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA042483 Approved Not detected epididymis: 0.0 -VN1R4 V1RL4 ENSG00000228567 Vomeronasal 1 receptor 4 19 53266676-53267723 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA027018 Uncertain Not detected testis: 0.5 -NUTM2E FAM22E ENSG00000228570 NUT family member 2E 10 79841358-79850878 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA064635 Uncertain Nuclear bodies Tissue enhanced 0 testis: 1.1 epididymis: 0.7 -C1orf233 ENSG00000228594 Chromosome 1 open reading frame 233 1 1598012-1600096 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enhanced 0 adrenal gland: 12.8 cerebral cortex: 9.5 -CLDN25 ENSG00000228607 Claudin 25 11 113779747-113780500 Predicted membrane proteins No evidence No evidence No evidence HPA053555 Uncertain Not detected epididymis: 0.1 -PROB1 C5orf65 ENSG00000228672 Proline-rich basic protein 1 5 139390592-139395713 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA060103 Supported Approved Nucleoplasm Tissue enhanced 0 skeletal muscle: 24.8 heart muscle: 6.3 -ARL17B ARL17 ENSG00000228696 ADP-ribosylation factor-like 17B 17 46274784-46361797 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046814 Uncertain Mixed ovary: 7.6 -DHFR ENSG00000228716 Dihydrofolate reductase 5 80626228-80654983 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037129, HPA051465 Uncertain Supported Mitochondria Mixed lymph node: 50.1 -SAPCD1 C6orf26, NG23 ENSG00000228727 Suppressor APC domain containing 1 6 31762799-31764851 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA071699 Approved Vesicles
Cell Junctions Tissue enhanced 0 skin: 3.2 bone marrow: 1.0 -CT45A5 CT45-5, CT45.5 ENSG00000228836 Cancer/testis antigen family 45, member A5 X 135777130-135785298 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Tissue enriched 62 testis: 8.6 cerebral cortex: 0.1 -USP17L30 ENSG00000228856 Ubiquitin specific peptidase 17-like family member 30 4 9363129-9364721 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA045642 Uncertain Not detected adipose tissue: 0.0 -TSPY3 CT78 ENSG00000228927 Testis specific protein, Y-linked 3 Y 9398421-9401223 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA049384 Supported Tissue enriched 43 testis: 4.3 adipose tissue: 0.0 -RPL41 L41 ENSG00000229117 Ribosomal protein L41 12 56116586-56117943 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053169 Approved Expressed in all ovary: 10553.2 -PGA4 ENSG00000229183 Pepsinogen 4, group I (pepsinogen A) 11 61222216-61231927 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046875 Supported Tissue enriched 4166 stomach: 27159.5 kidney: 6.5 -RFPL4AL1 ENSG00000229292 Ret finger protein-like 4A-like 1 19 55769141-55773179 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046368 Uncertain Approved Centrosome
Cytosol Not detected spleen: 0.6 -ORM1 ENSG00000229314 Orosomucoid 1 9 114323056-114326475 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB006265, HPA046438, HPA047725, HPA057726 Approved Approved Golgi apparatus
Vesicles Tissue enriched 69 liver: 10546.0 bone marrow: 152.7 -SFTA3 NANCI, SFTPH ENSG00000229415 Surfactant associated 3 14 36473288-36513829 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059427 Uncertain Group enriched 459 lung: 86.0;thyroid gland: 49.0 stomach: 0.1 -SPINK8 ENSG00000229453 Serine peptidase inhibitor, Kazal type 8 (putative) 3 48306842-48328341 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence HPA053151 Uncertain Tissue enriched 7 breast: 57.1 bone marrow: 7.7 -PATL2 Pat1a ENSG00000229474 Protein associated with topoisomerase II homolog 2 (yeast) 15 44665732-44711316 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 lymph node: 20.3;spleen: 19.6 appendix: 10.8 -NKX1-2 bB238F13.2, C10orf121 ENSG00000229544 NK1 homeobox 2 10 124445239-124450184 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA029367 Uncertain Not detected cerebral cortex: 0.7 -TSPY8 ENSG00000229549 Testis specific protein, Y-linked 8 Y 9357797-9380870 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA049384 Supported Tissue enriched 67 testis: 11.6 adipose tissue: 0.1 -PRAMEF25 ENSG00000229571 PRAME family member 25 1 13060853-13077884 Predicted intracellular proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -USP17L26 ENSG00000229579 Ubiquitin specific peptidase 17-like family member 26 4 9334658-9336609 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA045642 Uncertain Not detected adipose tissue: 0.0 -PRAC2 C17orf93, HOXB-AS5, HOXB13-AS1, NCRNA00253 ENSG00000229637 Prostate cancer susceptibility candidate 2 17 48723168-48724758 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 prostate: 19.0;rectum: 13.7 colon: 5.0 -PRR20C ENSG00000229665 Proline rich 20C 13 57140918-57157082 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA059485 Uncertain Not detected testis: 0.3 -ZNF492 KIAA1473, ZNF115 ENSG00000229676 Zinc finger protein 492 19 22634324-22667670 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 3.6 bone marrow: 1.6 -ZNF688 ENSG00000229809 Zinc finger protein 688 16 30569346-30572734 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA048922 Uncertain Approved Nucleoplasm
Plasma membrane
Cell Junctions Expressed in all testis: 23.9 -PET100 C19orf79 ENSG00000229833 PET100 homolog 19 7629737-7631956 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all adrenal gland: 54.9 -PGA3 ENSG00000229859 Pepsinogen 3, group I (pepsinogen A) 11 61203307-61213098 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB026358, HPA046875 Supported Tissue enriched 480 stomach: 35557.1 cerebral cortex: 74.0 -FAM90A26 FAM90A26P ENSG00000229924 Family with sequence similarity 90, member A26 4 9170409-9176730 Predicted intracellular proteins No evidence No evidence Not detected cerebral cortex: 0.2 -PRPS1L1 PRPS3, PRPSL ENSG00000229937 Phosphoribosyl pyrophosphate synthetase 1-like 1 7 18026774-18027863 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 550 testis: 55.0 adipose tissue: 0.0 -IQCF3 ENSG00000229972 IQ motif containing F3 3 51817604-51830856 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 245 testis: 72.1 cerebral cortex: 0.2 -POTEB2 ENSG00000230031 POTE ankyrin domain family, member B2 15 20835372-20866314 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA042822 Uncertain Tissue enriched 40 testis: 3.9 adipose tissue: 0.0 -ANKRD66 ENSG00000230062 Ankyrin repeat domain 66 6 46746917-46759506 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 13 fallopian tube: 63.1 lung: 4.9 -ACBD6 MGC2404 ENSG00000230124 Acyl-CoA binding domain containing 6 1 180269653-180502954 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028179, HPA028457 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 42.0 -OR4F3 ENSG00000230178 Olfactory receptor, family 4, subfamily F, member 3 5 181367268-181368262 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA047705 Uncertain Not detected testis: 0.6 -OR5H6 ENSG00000230301 Olfactory receptor, family 5, subfamily H, member 6 (gene/pseudogene) 3 98264285-98265262 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -CT47A8 CT47.8 ENSG00000230347 Cancer/testis antigen family 47, member A8 X 120877490-120951744 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 21 testis: 2.0 adipose tissue: 0.0 -USP17L25 ENSG00000230430 Ubiquitin specific peptidase 17-like family member 25 4 9329911-9331862 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA045642 Uncertain Not detected adipose tissue: 0.0 -ANKRD18B bA255A11.3 ENSG00000230453 Ankyrin repeat domain 18B 9 33524394-33573009 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046346, HPA046695, HPA049923, HPA051288 Uncertain Approved Nucleoli
Cytosol Tissue enhanced 0 testis: 6.8 skin: 2.9 -PPP5D1 ENSG00000230510 PPP5 tetratricopeptide repeat domain containing 1 19 46480796-46601200 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA073186 Uncertain Cytosol Mixed cerebral cortex: 4.8 -MBD3L2 ENSG00000230522 Methyl-CpG binding domain protein 3-like 2 19 7049321-7051735 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA051259 Uncertain Not detected testis: 0.3 -USP17L1 USP17L1P ENSG00000230549 Ubiquitin specific peptidase 17-like family member 1 8 7332387-7333979 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected cerebral cortex: 0.3 -CT47A4 CT47.4 ENSG00000230594 Cancer/testis antigen family 47, member A4 X 120967886-120971208 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 21 testis: 2.0 adipose tissue: 0.0 -PRB4 ENSG00000230657 Proline-rich protein BstNI subfamily 4 12 11307083-11310435 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enriched 3406 salivary gland: 1288.8 testis: 0.3 -SETSIP SETP18 ENSG00000230667 SET-like protein 1 92074533-92075441 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA063683 Approved Supported Nucleoplasm
Lipid droplets Not detected testis: 0.4 -ANKRD63 ENSG00000230778 Ankyrin repeat domain 63 15 40281444-40282586 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enriched 6 cerebral cortex: 1.0 spleen: 0.1 -YY2 ZNF631 ENSG00000230797 YY2 transcription factor X 21855987-21858727 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA001119, HPA030335 Approved Approved Nuclear bodies Tissue enhanced 0 testis: 10.9 endometrium: 2.8 -STMND1 FLJ23152 ENSG00000230873 Stathmin domain containing 1 6 17102258-17131372 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA067970 Approved Actin filaments Tissue enhanced 0 fallopian tube: 33.3;testis: 12.3 gallbladder: 9.4 -HSBP1 ENSG00000230989 Heat shock factor binding protein 1 16 83807843-83819737 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all cerebral cortex: 59.0 -USP17L28 ENSG00000231051 Ubiquitin specific peptidase 17-like family member 28 4 9348893-9350485 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA045642 Uncertain Not detected adipose tissue: 0.0 -KRTAP21-3 ENSG00000231068 Keratin associated protein 21-3 21 30718525-30718777 Predicted intracellular proteins No evidence No evidence No evidence HPA046554 Uncertain Not detected adipose tissue: 0.0 -OR5H1 HSHTPCRX14, HTPCRX14 ENSG00000231192 Olfactory receptor, family 5, subfamily H, member 1 3 98132698-98133639 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -PLSCR5 ENSG00000231213 Phospholipid scramblase family, member 5 3 146576555-146606216 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047249 Uncertain Tissue enriched 5 parathyroid gland: 1.7 testis: 0.3 -C17orf105 ENSG00000231256 Chromosome 17 open reading frame 105 17 43780435-43787612 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053028 Approved Tissue enriched 46 testis: 20.2 skin: 0.4 -SBK3 SgK110 ENSG00000231274 SH3 domain binding kinase family, member 3 19 55540656-55545543 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 8 heart muscle: 22.6 adipose tissue: 2.7 -HLA-DPA1 HLA-DP1A ENSG00000231389 Major histocompatibility complex, class II, DP alpha 1 6 33064569-33080775 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017967 Supported Supported Vesicles Expressed in all lung: 122.4 -USP17L10 ENSG00000231396 Ubiquitin specific peptidase 17-like family member 10 4 9210657-9212608 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -RPS18 D6S218E, HKE3, KE-3, KE3, S18 ENSG00000231500 Ribosomal protein S18 6 33272010-33276510 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050159, HPA055007 Approved Supported Cytosol Expressed in all ovary: 1301.5 -USP17L29 ENSG00000231637 Ubiquitin specific peptidase 17-like family member 29 4 9353638-9355230 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA045642 Uncertain Not detected adipose tissue: 0.0 -DIRC3 FLJ14199 ENSG00000231672 Disrupted in renal carcinoma 3 2 217284019-217756593 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 parathyroid gland: 1.2 testis: 0.7 -TSPAN19 ENSG00000231738 Tetraspanin 19 12 85014311-85036277 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA057066 Uncertain Tissue enhanced 0 testis: 8.3 lung: 4.6 -C18orf42 ENSG00000231824 Chromosome 18 open reading frame 42 18 5145285-5197503 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049365 Uncertain Tissue enriched 11 adrenal gland: 20.2 testis: 1.7 -CYP21A2 CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B ENSG00000231852 Cytochrome P450, family 21, subfamily A, polypeptide 2 6 32038265-32041670 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048979, HPA053371 Supported Tissue enriched 386 adrenal gland: 267.2 epididymis: 0.6 -OR5K2 ENSG00000231861 Olfactory receptor, family 5, subfamily K, member 2 3 98497604-98498663 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected smooth muscle: 0.5 -PRH1 Pa ENSG00000231887 Proline-rich protein HaeIII subfamily 1 12 10824960-11171544 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enriched 2279 salivary gland: 18012.3 ovary: 7.9 -PSG1 CD66f, PBG1, PSBG1, PSGGA ENSG00000231924 Pregnancy specific beta-1-glycoprotein 1 19 42866464-42879822 CD markers, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046327 Approved Tissue enriched 383 placenta: 362.6 smooth muscle: 0.9 -TAPBP TAPA ENSG00000231925 TAP binding protein (tapasin) 6 33299694-33314387 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007066 Approved Expressed in all spleen: 31.4 -MAGEB6P1 MAGEB6B ENSG00000232030 Melanoma antigen family B6 pseudogene 1 X 26160601-26161824 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.8 -ZBED9 Buster4, FLJ31087, KIAA1925, SCAND3, ZFP38-L, ZNF305P2, ZNF452 ENSG00000232040 Zinc finger, BED-type containing 9 6 28571630-28616212 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA007246 Uncertain Approved Nucleus
Nucleoli
Golgi apparatus Tissue enhanced 0 testis: 18.7 epididymis: 4.5 -TMEM253 C14orf176, C14orf95, NCRNA00220 ENSG00000232070 Transmembrane protein 253 14 21098937-21103724 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA052329, HPA065092 Supported Group enriched 7 duodenum: 104.1;small intestine: 102.1 colon: 15.8 -TMA7 CCDC72, HSPC016 ENSG00000232112 Translation machinery associated 7 homolog 3 48440257-48444208 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047397 Approved Approved Nucleus
Nucleoli
Nuclear bodies Expressed in all epididymis: 420.8 -MCTS1 MCT-1 ENSG00000232119 Malignant T cell amplified sequence 1 X 120594010-120621074 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001045 Supported Plasma membrane
Cytosol Expressed in all thyroid gland: 50.5 -DYTN ENSG00000232125 Dystrotelin 2 206651621-206718396 Predicted intracellular proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level Not detected bone marrow: 0.1 -MTRNR2L4 ENSG00000232196 MT-RNR2-like 4 16 3370979-3372740 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all skeletal muscle: 98.2 -ASCL5 bHLHa47 ENSG00000232237 Achaete-scute family bHLH transcription factor 5 1 201113953-201127184 Predicted intracellular proteins, Transcription factors No evidence No evidence No evidence Not detected endometrium: 0.6 -TMEM114 ENSG00000232258 Transmembrane protein 114 16 8537605-8590193 Disease related genes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 62 seminal vesicle: 28.3 epididymis: 0.4 -KRTAP25-1 KAP25.1 ENSG00000232263 Keratin associated protein 25-1 21 30289145-30289514 Predicted intracellular proteins No evidence No evidence No evidence HPA031438 Uncertain Approved Nuclear membrane
Plasma membrane
Cytosol Not detected adipose tissue: 0.0 -USP17L24 ENSG00000232264 Ubiquitin specific peptidase 17-like family member 24 4 9325165-9327116 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA045642 Uncertain Not detected adipose tissue: 0.0 -OR52I1 ENSG00000232268 Olfactory receptor, family 52, subfamily I, member 1 11 4593750-4595013 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -OR5K1 HSHTPCRX10, HTPCRX10 ENSG00000232382 Olfactory receptor, family 5, subfamily K, member 1 3 98469480-98470576 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -LINC00493 LOC388789 ENSG00000232388 Long intergenic non-protein coding RNA 493 20 18567347-18569563 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA068733 Approved Nucleoplasm
Cytosol Expressed in all epididymis: 155.5 -USP17L13 ENSG00000232399 Ubiquitin specific peptidase 17-like family member 13 4 9224896-9226847 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -PRAMEF6 ENSG00000232423 PRAME family member 6 1 12938472-13056491 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -C9orf172 ENSG00000232434 Chromosome 9 open reading frame 172 9 136844415-136848801 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA021200 Uncertain Approved Focal adhesion sites
Cytosol Tissue enhanced 0 cerebral cortex: 7.4 spleen: 3.4 -HLA-DQB2 HLA-DXB ENSG00000232629 Major histocompatibility complex, class II, DQ beta 2 6 32756098-32763534 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lung: 8.2;skin: 13.3 tonsil: 6.1 -GOLGA8N ENSG00000232653 Golgin A8 family, member N 15 32593456-32607310 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Expressed in all thyroid gland: 46.4 -TNF DIF, TNF-alpha, TNFA, TNFSF2 ENSG00000232810 Tumor necrosis factor 6 31575567-31578336 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 3.7 lymph node: 1.3 -PET117 ENSG00000232838 PET117 homolog 20 18137873-18143169 Predicted secreted proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA047716 Approved Expressed in all cerebral cortex: 24.1 -LYRM9 C17orf108, HSD24 ENSG00000232859 LYR motif containing 9 17 27878314-27894752 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA023051 Uncertain Expressed in all thyroid gland: 71.7 -DEFB130 DEFB-30, DEFB30 ENSG00000232948 Defensin, beta 130 8 12310962-12318316 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 46 epididymis: 4.6 adipose tissue: 0.0 -RP11-1212A22.4 ENSG00000233024 16 18358086-18379331 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level HPA053611 Approved Uncertain Nucleoplasm Expressed in all parathyroid gland: 129.0 -PHGR1 ENSG00000233041 Proline/histidine/glycine-rich 1 15 40351033-40356434 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA068787 Supported Approved Vesicles Group enriched 7 colon: 1475.8;duodenum: 917.9;rectum: 408.6;small intestine: 1813.6 stomach: 170.7 -RP11-1236K1.1 ENSG00000233050 8 12064389-12071747 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enriched 46 epididymis: 4.6 adipose tissue: 0.0 -USP17L11 ENSG00000233136 Ubiquitin specific peptidase 17-like family member 11 4 9215405-9217356 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA045642 Uncertain Tissue enriched 11 epididymis: 2.2 thyroid gland: 0.2 -RNF224 ENSG00000233198 Ring finger protein 224 9 137227271-137229638 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Mixed fallopian tube: 1.2 -NPIPB7 LOC440350, NPIPL1 ENSG00000233232 Nuclear pore complex interacting protein family, member B7 16 28456372-28471175 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA011188, HPA053611 Approved Approved Nucleoplasm Tissue enriched 25 testis: 16.3 skin: 0.6 -GPX1 ENSG00000233276 Glutathione peroxidase 1 3 49357176-49358600 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011582, HPA044758 Approved Supported Cytosol Expressed in all adipose tissue: 275.5 -OR5H15 ENSG00000233412 Olfactory receptor, family 5, subfamily H, member 15 3 98168700-98198138 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.3 -BTBD18 ENSG00000233436 BTB (POZ) domain containing 18 11 57743514-57751781 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA049325 Uncertain Tissue enriched 8 testis: 4.1 epididymis: 0.5 -AC109829.1 ENSG00000233438 2 27537386-27567144 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 8.1 epididymis: 1.6 -TMEM238 ENSG00000233493 Transmembrane protein 238 19 55379245-55384598 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 small intestine: 10.2;stomach: 10.2 colon: 9.4 -TWIST2 bHLHa39, Dermo-1, DERMO1 ENSG00000233608 Twist family bHLH transcription factor 2 2 238848032-238910543 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062870 Supported Nucleus
Nucleoli Tissue enhanced 0 cervix, uterine: 40.2 adipose tissue: 27.3 -PIRT ENSG00000233670 Phosphoinositide-interacting regulator of transient receptor potential channels 17 10822475-10838445 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042337 Uncertain Uncertain Plasma membrane
Cytosol Tissue enhanced 0 adrenal gland: 3.1;cerebral cortex: 2.7;rectum: 2.7 colon: 2.1 -PRR23C FLJ46210 ENSG00000233701 Proline rich 23C 3 139042102-139044892 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047473 Uncertain Tissue enriched 12 testis: 1.7 spleen: 0.1 -AC092835.2 ENSG00000233757 2 95207535-95259774 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed testis: 3.9 -TRIM49D2 TRIM49D2P, TRIM49L, TRIM49L1 ENSG00000233802 Tripartite motif containing 49D2 11 89924064-89933063 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.2 -TSPY4 ENSG00000233803 Testis specific protein, Y-linked 4 Y 9337464-9340284 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA049384 Supported Tissue enriched 200 testis: 19.9 adipose tissue: 0.0 -IFNA13 ENSG00000233816 Interferon, alpha 13 9 21367424-21368962 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected epididymis: 0.6 -HIST1H2BN H2B/d, H2BFD ENSG00000233822 Histone cluster 1, H2bn 6 27837760-27865798 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed testis: 3.9 -POTEB A26B1, CT104.5, POTE-15, POTE15 ENSG00000233917 POTE ankyrin domain family, member B 15 21846329-21877703 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042822 Uncertain Tissue enriched 10 testis: 1.0 epididymis: 0.0 -RPS28 S28 ENSG00000233927 Ribosomal protein S28 19 8321158-8323340 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047132 Approved Approved Cytosol Expressed in all ovary: 306.8 -CTXN2 ENSG00000233932 Cortexin 2 15 48191539-48203756 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA053168 Uncertain Group enriched 8 cerebral cortex: 1.9;testis: 1.5 fallopian tube: 0.2 -UQCRHL ENSG00000233954 Ubiquinol-cytochrome c reductase hinge protein like 1 15807169-15809348 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA042574 Approved Mixed skin: 1.3 -PAGE2 CT16.4, GAGEC2, MGC62094, PAGE-2 ENSG00000234068 P antigen family, member 2 (prostate associated) X 55089008-55092842 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA052619 Supported Tissue enriched 42 testis: 43.6 placenta: 1.0 -TRIM26 RNF95, ZNF173 ENSG00000234127 Tripartite motif containing 26 6 30184455-30213427 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044975, HPA050456 Approved Supported Nucleoplasm
Cytosol Mixed fallopian tube: 10.3 -TMEM229A ENSG00000234224 Transmembrane protein 229A 7 124030916-124033023 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA056391 Uncertain Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 7.1;duodenum: 8.9;testis: 10.4 small intestine: 4.4 -PRR20E ENSG00000234278 Proline rich 20E 13 57167197-57170218 Predicted intracellular proteins No evidence No evidence No evidence HPA059485 Uncertain Not detected testis: 0.1 -ZNF879 DKFZp686E2433 ENSG00000234284 Zinc finger protein 879 5 179023752-179035064 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA068608 Uncertain Approved Nucleus Mixed testis: 11.2 -H2BFS ENSG00000234289 H2B histone family, member S (pseudogene) 21 43565189-43565648 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed prostate: 15.0 -CCDC188 ENSG00000234409 Coiled-coil domain containing 188 22 20148427-20151065 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA049901 Approved Nucleoplasm
Nuclear bodies Tissue enriched 10 testis: 18.2 spleen: 1.9 -RBMY1A1 RBM1, RBM2, YRRM1, YRRM2 ENSG00000234414 RNA binding motif protein, Y-linked, family 1, member A1 Y 21511372-21549326 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA001534, HPA053147 Supported Tissue enriched 125 testis: 16.8 epididymis: 0.1 -KBTBD13 hCG_1645727, NEM6 ENSG00000234438 Kelch repeat and BTB (POZ) domain containing 13 15 65076816-65078192 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062737 Uncertain Tissue enriched 11 skeletal muscle: 5.2 heart muscle: 0.4 -ZNF736 ENSG00000234444 Zinc finger protein 736 7 64307459-64354860 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA051027, HPA061215 Uncertain Uncertain Nucleoplasm Mixed testis: 15.6 -PINLYP ENSG00000234465 Phospholipase A2 inhibitor and LY6/PLAUR domain containing 19 43576800-43583964 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA061218 Uncertain Approved Vesicles Mixed fallopian tube: 27.4 -CLDN34 ENSG00000234469 Claudin 34 X 9967358-9968352 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 13 testis: 2.3 epididymis: 0.1 -FAM133B MGC40405 ENSG00000234545 Family with sequence similarity 133, member B 7 92560793-92590394 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA066175, HPA069513 Approved Nucleus
Nucleoli Expressed in all epididymis: 34.4 -OR10G8 ENSG00000234560 Olfactory receptor, family 10, subfamily G, member 8 11 124029590-124030634 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -MCIDAS IDAS, MCI, MCIN ENSG00000234602 Multiciliate differentiation and DNA synthesis associated cell cycle protein 5 55219614-55227315 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049981, HPA058073 Uncertain Supported Nuclear bodies Not detected testis: 0.1 -JRK jerky, JH8 ENSG00000234616 Jrk helix-turn-helix protein 8 142657460-142681968 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA052675 Approved Nucleus
Nucleoli
Nuclear bodies Mixed testis: 10.9 -RP11-166B2.1 ENSG00000234719 Putative NPIP-like protein LOC729978 16 11927373-11976643 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA053611 Supported Approved Nucleoplasm Tissue enhanced 0 testis: 15.4 parathyroid gland: 8.9 -HLA-B AS ENSG00000234745 Major histocompatibility complex, class I, B 6 31353872-31357188 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015418 Supported Mixed lung: 1245.1 -C11orf94 ENSG00000234776 Chromosome 11 open reading frame 94 11 45906513-45907282 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 55 testis: 20.6 thyroid gland: 0.3 -IFNA17 IFN-alphaI, LEIF2C1 ENSG00000234829 Interferon, alpha 17 9 21227243-21228222 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected adipose tissue: 0.0 -APOC2 ENSG00000234906 Apolipoprotein C-II 19 44946035-44949565 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055877 Supported Tissue enriched 40 liver: 257.4 small intestine: 6.4 -SHISA8 C22orf17, Orf26 ENSG00000234965 Shisa family member 8 22 41909554-41914667 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA059173 Uncertain Tissue enhanced 0 adrenal gland: 4.4 lymph node: 1.4 -C19orf81 ENSG00000235034 Chromosome 19 open reading frame 81 19 50649445-50659310 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA060238 Supported Approved Vesicles
Aggresome Tissue enriched 11 testis: 5.3 epididymis: 0.4 -ANKRD65 ENSG00000235098 Ankyrin repeat domain 65 1 1418420-1421769 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA065720 Approved Approved Nucleoplasm Tissue enhanced 0 fallopian tube: 60.1 seminal vesicle: 31.8 -ZSCAN31 ZNF310P, ZNF323 ENSG00000235109 Zinc finger and SCAN domain containing 31 6 28324693-28356271 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007124 Approved Approved Nucleoplasm
Cytosol Expressed in all testis: 40.7 -TMEM30C CDC50C ENSG00000235156 Transmembrane protein 30C 3 100185824-100194191 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enriched 8 testis: 2.6 skin: 0.3 -C12orf75 AGD3, OCC-1, OCC1 ENSG00000235162 Chromosome 12 open reading frame 75 12 105235290-105396097 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065311 Uncertain Approved Vesicles Tissue enhanced 0 seminal vesicle: 137.0 prostate: 64.3 -SMIM1 Vel ENSG00000235169 Small integral membrane protein 1 (Vel blood group) 1 3772788-3775982 Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069088 Uncertain Tissue enhanced 0 bone marrow: 17.6;testis: 24.7 seminal vesicle: 7.5 -HGH1 C8orf30A, C8orf30B, FAM203A, FAM203B, FLJ40907, LOC51236 ENSG00000235173 HGH1 homolog 8 144137769-144140843 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042470 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Mixed adipose tissue: 2.6 -PPP1R3E FLJ00089 ENSG00000235194 Protein phosphatase 1, regulatory subunit 3E 14 23295643-23302848 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061600 Approved Approved Microtubules
Mitochondria Mixed testis: 14.5 -KDM4E JMJD2E, KDM4DL ENSG00000235268 Lysine (K)-specific demethylase 4E 11 95025258-95027596 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA051740, HPA054225 Uncertain Not detected testis: 0.4 -RPEL1 ENSG00000235376 Ribulose-5-phosphate-3-epimerase-like 1 10 103245887-103248016 Enzymes, Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA036498, HPA036499 Approved Not detected adipose tissue: 0.0 -NFAM1 CNAIP ENSG00000235568 NFAT activating protein with ITAM motif 1 22 42380410-42432395 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031812 Uncertain Tissue enhanced 0 appendix: 17.6;bone marrow: 20.3 spleen: 14.8 -NKX1-1 HSPX153, SAX2 ENSG00000235608 NK1 homeobox 1 4 1402932-1406331 Predicted intracellular proteins, Transcription factors Evidence at transcript level No evidence Evidence at transcript level HPA029367 Uncertain Not detected testis: 0.1 -RNF148 MGC35222 ENSG00000235631 Ring finger protein 148 7 122701664-122702967 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 226 testis: 73.0 lung: 0.3 -ANKRD34C ENSG00000235711 Ankyrin repeat domain 34C 15 79293285-79298235 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA045329 Uncertain Approved Mitochondria Tissue enhanced 0 cerebral cortex: 1.9 skin: 0.9 -MFRP C1QTNF5, FLJ30570, NNO2, rd6 ENSG00000235718 Membrane frizzled-related protein 11 119338942-119346673 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level HPA042946 Uncertain Not detected parathyroid gland: 0.2 -KIAA0040 ENSG00000235750 KIAA0040 1 175156987-175192999 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016895, HPA068812 Approved Approved Nucleoplasm Expressed in all placenta: 142.4 -USP17L27 ENSG00000235780 Ubiquitin specific peptidase 17-like family member 27 4 9344148-9345740 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA045642 Uncertain Not detected adipose tissue: 0.0 -B3GALT4 beta3Gal-T4, GalT4 ENSG00000235863 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 6 33277132-33284832 Enzymes, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043001 Approved Mixed testis: 3.8 -LCE6A C1orf44 ENSG00000235942 Late cornified envelope 6A 1 152842868-152843983 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA046376 Supported Tissue enriched 11 skin: 303.6 breast: 26.4 -PNMA6A MGC15827, PNMA6C ENSG00000235961 Paraneoplastic Ma antigen family member 6A X 153072482-153075018 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045007, HPA052115 Uncertain Uncertain Nucleoli
Mitochondria Tissue enhanced 0 cerebral cortex: 22.9 epididymis: 9.3 -PATE3 HEL-127, PATE-DJ ENSG00000236027 Prostate and testis expressed 3 11 125788111-125791600 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 28 epididymis: 186.8 seminal vesicle: 6.6 -OR5H14 ENSG00000236032 Olfactory receptor, family 5, subfamily H, member 14 3 98149326-98150405 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.3 -ZBTB22 BING1, fru, fruitless, ZBTB22A, ZNF297, ZNF297A ENSG00000236104 Zinc finger and BTB domain containing 22 6 33314406-33317942 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA043848 Approved Nucleoplasm Tissue enhanced 0 parathyroid gland: 28.5 epididymis: 11.7 -USP17L4 ENSG00000236125 Ubiquitin specific peptidase 17-like family member 4 8 7337115-7338707 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -CT47A3 CT47.3 ENSG00000236126 Cancer/testis antigen family 47, member A3 X 120972746-120976068 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 21 testis: 2.0 adipose tissue: 0.0 -CLEC2L FLJ32986 ENSG00000236279 C-type lectin domain family 2, member L 7 139523856-139544984 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA045050 Supported Group enriched 9 cerebral cortex: 21.0;parathyroid gland: 13.4 endometrium: 1.9 -ZBED5 Buster1 ENSG00000236287 Zinc finger, BED-type containing 5 11 10812074-10858796 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA048472, HPA050994 Uncertain Approved Nucleus
Nucleoli fibrillar center
Golgi apparatus Expressed in all parathyroid gland: 94.8 -SLFN14 ENSG00000236320 Schlafen family member 14 17 35548125-35558098 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA022994, HPA023065 Uncertain Tissue enhanced 0 bone marrow: 2.5 lymph node: 0.6 -PPIAL4G ENSG00000236334 Peptidylprolyl isomerase A (cyclophilin A)-like 4G 1 148479824-148483679 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence No evidence Evidence at protein level HPA058345 Uncertain Not detected skeletal muscle: 0.9 -GAGE12F ENSG00000236362 G antigen 12F X 49560876-49568205 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Cytosol Tissue enriched 12 testis: 124.2 stomach: 10.2 -CT47A1 CT47.1 ENSG00000236371 Cancer/testis antigen family 47, member A1 X 120982466-120985788 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 11 testis: 1.1 adipose tissue: 0.0 -TAS2R39 ENSG00000236398 Taste receptor, type 2, member 39 7 143183419-143184435 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA053456, HPA060680 Uncertain Not detected adipose tissue: 0.0 -TSPY10 ENSG00000236424 Testis specific protein, Y-linked 10 Y 9527880-9530682 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA049384 Supported Tissue enriched 51 testis: 5.1 adipose tissue: 0.0 -CT47B1 CT47.13 ENSG00000236446 Cancer/testis antigen family 47, member B1 X 120872603-120875929 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA042483 Approved Tissue enriched 45 testis: 4.4 adipose tissue: 0.0 -ZNF853 DKFZp434J1015 ENSG00000236609 Zinc finger protein 853 7 6615617-6624290 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA067690 Approved Approved Nucleoli Mixed cerebral cortex: 17.4 -IFNA4 IFN-alpha4a, MGC142200 ENSG00000236637 Interferon, alpha 4 9 21186694-21228173 Predicted secreted proteins Evidence at protein level No evidence Evidence at protein level HPA047557 Uncertain Not detected adipose tissue: 0.0 -ARHGEF38 FLJ20184 ENSG00000236699 Rho guanine nucleotide exchange factor (GEF) 38 4 105552620-105708093 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA036510, HPA045484 Approved Approved Nucleoplasm
Centrosome Tissue enhanced 0 breast: 9.9 prostate: 8.4 -GAGE12B ENSG00000236737 G antigen 12B X 49529869-49529985 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 duodenum: 1.2 spleen: 0.4 -CTAGE9 ENSG00000236761 CTAGE family, member 9 6 131708684-131711017 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA000387, HPA000922 Uncertain Tissue enriched 40 testis: 7.6 seminal vesicle: 0.1 -RP11-96L14.7 ENSG00000236782 1 26169516-26171821 Predicted membrane proteins No evidence No evidence Not detected adipose tissue: 0.2 -C3orf84 ENSG00000236980 Chromosome 3 open reading frame 84 3 49177632-49191858 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 32 testis: 7.6 epididymis: 0.2 -OR10G9 OR10G10P ENSG00000236981 Olfactory receptor, family 10, subfamily G, member 9 11 124023013-124023948 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -USP17L8 ENSG00000237038 Ubiquitin specific peptidase 17-like family member 8 8 7971661-7977985 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -TAAR9 TA3, TAR3, TRAR3 ENSG00000237110 Trace amine associated receptor 9 (gene/pseudogene) 6 132538290-132539336 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -C4orf51 ENSG00000237136 Chromosome 4 open reading frame 51 4 145680204-145771032 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA050068 Uncertain Tissue enriched 15 testis: 10.4 epididymis: 0.6 -B3GNT9 MGC4655 ENSG00000237172 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 16 67148105-67151214 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA052743, HPA062734 Approved Supported Nucleoli fibrillar center
Golgi apparatus Tissue enhanced 0 parathyroid gland: 47.3 thyroid gland: 27.9 -CDKN2AIPNL MGC13017 ENSG00000237190 CDKN2A interacting protein N-terminal like 5 134402087-134411898 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043966 Approved Expressed in all thyroid gland: 35.3 -MBD3L5 ENSG00000237247 Methyl-CpG binding domain protein 3-like 5 19 7030577-7033011 Predicted intracellular proteins No evidence No evidence No evidence HPA051259 Uncertain Not detected adipose tissue: 0.0 -CKMT1B CKMT, CKMT1, UMTCK ENSG00000237289 Creatine kinase, mitochondrial 1B 15 43593054-43604901 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043491 Uncertain Tissue enhanced 0 colon: 79.4;rectum: 69.8 duodenum: 64.7 -RNF223 ENSG00000237330 Ring finger protein 223 1 1070966-1074307 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 esophagus: 5.3;stomach: 3.7 skin: 2.0 -PATE4 FLJ41047, PATE-B ENSG00000237353 Prostate and testis expressed 4 11 125833316-125840069 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA045632 Approved Tissue enriched 8 seminal vesicle: 147.1 epididymis: 18.4 -OR4A47 ENSG00000237388 Olfactory receptor, family 4, subfamily A, member 47 11 48488717-48489780 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA059763 Uncertain Not detected adipose tissue: 0.0 -PRSS56 ENSG00000237412 Protease, serine, 56 2 232520463-232525716 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skeletal muscle: 3.4 testis: 0.8 -ZNF737 ZNF102 ENSG00000237440 Zinc finger protein 737 19 20535825-20565809 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed thyroid gland: 66.8 -RGL2 HKE1.5, KE1.5, RAB2L ENSG00000237441 Ral guanine nucleotide dissociation stimulator-like 2 6 33291654-33299324 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053444 Approved Mixed spleen: 1.6 -BHMG1 HMGDC ENSG00000237452 Basic helix-loop-helix and HMG box domain containing 1 19 45733251-45764534 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA049521 Uncertain Tissue enriched 77 testis: 7.6 adipose tissue: 0.0 -SHISA9 ENSG00000237515 Shisa family member 9 16 12901620-13240413 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA072399 Approved Endoplasmic reticulum Tissue enhanced 0 cerebral cortex: 23.0 prostate: 7.7 -OR7E24 HSHT2, OR19-8, OR7E24P, OR7E24Q ENSG00000237521 Olfactory receptor, family 7, subfamily E, member 24 19 9250930-9252479 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 25 testis: 2.5 adipose tissue: 0.0 -HLA-DQA2 HLA-DXA ENSG00000237541 Major histocompatibility complex, class II, DQ alpha 2 6 32741342-32747215 Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected tonsil: 0.3 -KIFC1 HSET, KNSL2 ENSG00000237649 Kinesin family member C1 6 33391536-33409924 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055997, HPA062674 Supported Approved Centrosome Tissue enhanced 0 lymph node: 3.2 bone marrow: 2.8 -C2orf74 LOC339804 ENSG00000237651 Chromosome 2 open reading frame 74 2 61145068-61164829 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA026826 Approved Approved Centrosome Expressed in all testis: 80.2 -GAGE12C ENSG00000237671 G antigen 12C X 49532211-49539538 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enriched 472 testis: 47.1 adipose tissue: 0.0 -IRGM IFI1, IRGM1, LRG-47, LRG47 ENSG00000237693 Immunity-related GTPase family, M 5 150846523-150900736 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 1.7 spleen: 0.5 -AMY1A AMY1 ENSG00000237763 Amylase, alpha 1A (salivary) 1 103655290-103664554 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB004310, HPA045394, HPA045399, HPA046980 Supported Tissue enriched 80 salivary gland: 8907.0 cervix: 111.5 -FAM200B C4orf53 ENSG00000237765 Family with sequence similarity 200, member B 4 15681662-15705565 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA017855 Uncertain Mixed thyroid gland: 15.0 -FAM231A ENSG00000237847 Family with sequence similarity 231, member A 1 16673003-16673512 Predicted intracellular proteins No evidence No evidence No evidence HPA043267, HPA043292, HPA077864 Uncertain Approved Cytosol Not detected testis: 0.2 -CT47A5 CT47.5 ENSG00000237957 Cancer/testis antigen family 47, member A5 X 120958165-120966348 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 24 testis: 2.3 adipose tissue: 0.0 -TSPY9P TSPY9 ENSG00000238074 Testis specific protein, Y-linked 9, pseudogene Y 9487286-9490081 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA049384 Supported Tissue enriched 111 testis: 31.4 spleen: 0.2 -LRRC37A2 FLJ45049 ENSG00000238083 Leucine rich repeat containing 37, member A2 17 46511511-46555650 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042121, HPA042701, HPA043056, HPA045090, HPA049080 Supported Approved Vesicles Tissue enriched 35 testis: 11.8 bone marrow: 0.3 -C9orf69 bA83N9.1 ENSG00000238227 Chromosome 9 open reading frame 69 9 136114581-136118863 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA066070 Supported Supported Nucleoplasm Expressed in all skin: 23.8 -OR2W3 OR2W3P, OR2W8P, OST718 ENSG00000238243 Olfactory receptor, family 2, subfamily W, member 3 1 247895587-247896531 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045594 Uncertain Tissue enhanced 0 bone marrow: 7.8;thyroid gland: 10.5 cerebral cortex: 2.9 -PAGE2B CT16.5 ENSG00000238269 P antigen family, member 2B X 55075063-55078909 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA052619 Supported Tissue enriched 29 testis: 84.3 bone marrow: 2.8 -TXNDC5 EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15 ENSG00000239264 Thioredoxin domain containing 5 (endoplasmic reticulum) 6 7881517-7910814 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034677, HPA034678 Supported Approved Endoplasmic reticulum Expressed in all urinary bladder: 323.2 -GATSL3 ENSG00000239282 GATS protein-like 3 22 30285117-30289627 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed esophagus: 22.9 -RNF103 hkf-1, KF1, ZFP103 ENSG00000239305 Ring finger protein 103 2 86603393-86623866 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA057922 Approved Expressed in all epididymis: 54.2 -RBM14 COAA, DKFZp779J0927, SIP, SYTIP1 ENSG00000239306 RNA binding motif protein 14 11 66616582-66627347 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006628 Supported Supported Nuclear speckles Expressed in all testis: 49.9 -ALKBH6 MGC15677 ENSG00000239382 AlkB homolog 6 19 36009120-36014239 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA073835, HPA074340 Supported Nucleoplasm
Focal adhesion sites Mixed cerebral cortex: 7.5 -ASB14 DKFZp313L0121 ENSG00000239388 Ankyrin repeat and SOCS box containing 14 3 57268347-57292682 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skeletal muscle: 9.9 heart muscle: 2.2 -PCDHA13 CNR5, CNRN5, CNRS5, CRNR5, PCDH-ALPHA13 ENSG00000239389 Protocadherin alpha 13 5 140882208-141012344 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 6 parathyroid gland: 6.9 testis: 1.1 -KLHL41 KBTBD10, Krp1, SARCOSIN ENSG00000239474 Kelch-like family member 41 2 169509702-169526262 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021165, HPA021753, HPA021760 Supported Supported Nucleus
Plasma membrane
Cytosol Tissue enriched 22 skeletal muscle: 1750.9 esophagus: 80.0 -POM121L7 ENSG00000239511 POM121 transmembrane nucleoporin-like 7 22 21125660-21128063 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 104 testis: 53.0 appendix: 0.5 -GATS DKFZp686B07267, STAG3OS ENSG00000239521 GATS, stromal antigen 3 opposite strand 7 100200653-100272218 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA043176 Uncertain Tissue enhanced 0 cerebral cortex: 3.3;skeletal muscle: 2.2 bone marrow: 0.7 -OR1J4 HSHTPCRX01, HTPCRX01 ENSG00000239590 Olfactory receptor, family 1, subfamily J, member 4 9 122519141-122520082 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.2 -C2orf61 FLJ40172 ENSG00000239605 Chromosome 2 open reading frame 61 2 47045538-47155378 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047366, HPA052691 Approved Approved Nucleoplasm
Cytosol Tissue enriched 67 testis: 23.4 gallbladder: 0.3 -MEIKIN ENSG00000239642 Meiotic kinetochore factor 5 131806993-131945698 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 19 testis: 13.3 parathyroid gland: 0.6 -NME1 NDPKA, NM23, NM23-H1 ENSG00000239672 NME/NM23 nucleoside diphosphate kinase 1 17 51153536-51162428 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008467, CAB040571, HPA041113 Supported Validated Nucleoplasm
Cytosol Expressed in all cerebral cortex: 89.5 -TNFSF12 APO3L, DR3LG, TWEAK ENSG00000239697 Tumor necrosis factor (ligand) superfamily, member 12 17 7548891-7557890 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA052967 Uncertain Mixed seminal vesicle: 26.9 -CDRT4 FLJ36674 ENSG00000239704 CMT1A duplicated region transcript 4 17 15436015-15503608 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA021590 Uncertain Approved Mitochondria Mixed epididymis: 29.8 -APOBEC3G bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019 ENSG00000239713 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 22 39040961-39087743 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001812, HPA073637 Approved Uncertain Nucleoplasm
Cytosol Mixed lymph node: 52.0 -TLR9 CD289 ENSG00000239732 Toll-like receptor 9 3 52221080-52226163 CD markers, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 lymph node: 3.0 spleen: 2.0 -WBP1 WBP-1 ENSG00000239779 WW domain binding protein 1 2 74458329-74460891 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA057067 Approved Approved Cytosol Expressed in all thyroid gland: 91.2 -MRPS17 HSPC011, MRP-S17, RPMS17 ENSG00000239789 Mitochondrial ribosomal protein S17 7 55951819-55956501 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047159 Approved Expressed in all fallopian tube: 16.1 -PRAMEF11 ENSG00000239810 PRAME family member 11 1 12824605-12831410 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.4 -DEFA3 DEF3, HNP-3 ENSG00000239839 Defensin, alpha 3, neutrophil-specific 8 6996837-7018301 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052517 Supported Tissue enriched 189 bone marrow: 23349.1 spleen: 123.6 -GET4 C7orf20, CEE, CGI-20, H_NH1244M04.5, TRC35 ENSG00000239857 Golgi to ER traffic protein 4 7 876552-896436 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019765 Uncertain Supported Nucleoplasm
Nucleoli
Cytosol Expressed in all testis: 49.8 -KRTAP9-2 KAP9.2 ENSG00000239886 Keratin associated protein 9-2 17 41226648-41227652 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected testis: 0.1 -C1orf226 FLJ13137 ENSG00000239887 Chromosome 1 open reading frame 226 1 162366908-162386818 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052251 Approved Approved Nucleoplasm Mixed adrenal gland: 12.8 -ADSL ENSG00000239900 Adenylosuccinate lyase 22 40346500-40369367 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000525, CAB019285 Supported Validated Cytosol Expressed in all skeletal muscle: 118.1 -LILRA4 CD85g, ILT7 ENSG00000239961 Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 19 54333185-54339150 CD markers, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049418 Approved Tissue enhanced 0 spleen: 2.1;tonsil: 2.6 lymph node: 0.9 -LILRA2 CD85h, ILT1, LIR-7, LIR7 ENSG00000239998 Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 19 54572920-54590287 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 bone marrow: 9.9;spleen: 7.1 appendix: 4.1 -TEX35 C1orf49, DKFZP564J047, TSC24 ENSG00000240021 Testis expressed 35 1 178513077-178548602 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA039190 Approved Tissue enriched 28 testis: 174.3 epididymis: 6.1 -AMY2B AMY2 ENSG00000240038 Amylase, alpha 2B (pancreatic) 1 103553815-103579534 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045394, HPA045399, HPA046980 Supported Tissue enriched 66 pancreas: 6581.9 salivary gland: 100.2 -LY6G5B C6orf19, G5b ENSG00000240053 Lymphocyte antigen 6 complex, locus G5B 6 31670167-31673776 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048307 Approved Expressed in all skin: 27.1 -PSMB9 beta1i, LMP2, PSMB6i, RING12 ENSG00000240065 Proteasome subunit beta 9 6 32844136-32859585 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB015180, HPA042818, HPA053280 Supported Supported Cytosol Mixed spleen: 39.9 -PCDHGC3 PC-43, PC43, PCDH-GAMMA-C3, PCDH2 ENSG00000240184 Protocadherin gamma subfamily C, 3 5 141475947-141512979 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008755, HPA077289 Approved Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 377.1 cervix: 93.4 -SMKR1 ENSG00000240204 Small lysine-rich protein 1 7 129502479-129512932 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA078358 Approved Nucleoli Tissue enriched 13 testis: 119.3 fallopian tube: 9.3 -UGT1A5 UGT1E ENSG00000240224 UDP glucuronosyltransferase 1 family, polypeptide A5 2 233712992-233773299 Enzymes, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 7 duodenum: 7.7;gallbladder: 3.9;small intestine: 6.9 liver: 0.9 -COX19 MGC104475 ENSG00000240230 COX19 cytochrome c oxidase assembly factor 7 898778-975599 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021226 Approved Validated Cytosol Expressed in all fallopian tube: 9.9 -DEFA1B ENSG00000240247 Defensin, alpha 1B 8 6996766-7018289 Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA052517 Supported Tissue enriched 514 bone marrow: 61211.3 skin: 119.2 -ACAD11 FLJ12592 ENSG00000240303 Acyl-CoA dehydrogenase family, member 11 3 132558138-132660723 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048317 Supported Expressed in all kidney: 36.4 -PPIL3 CyPJ ENSG00000240344 Peptidylprolyl isomerase (cyclophilin)-like 3 2 200870907-200889303 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040765, HPA062187 Approved Supported Nucleus Expressed in all ovary: 45.4 -LCE1F LEP6 ENSG00000240386 Late cornified envelope 1F 1 152776372-152776728 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 21 skin: 246.3 breast: 11.8 -KIR3DL2 CD158K, cl-5, nkat4, nkat4a, nkat4b ENSG00000240403 Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 19 54850443-54867207 CD markers, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected bone marrow: 0.1 -KRTAP13-3 KAP13.3 ENSG00000240432 Keratin associated protein 13-3 21 30425265-30425968 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -TNFRSF13B CD267, IGAD2, TACI ENSG00000240505 Tumor necrosis factor receptor superfamily, member 13B 17 16929816-16972118 CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA030453 Uncertain Tissue enhanced 0 lymph node: 20.7;skeletal muscle: 22.1;spleen: 28.0;tonsil: 22.5 appendix: 12.5 -KRTAP9-1 KAP9.1, KRTAP9L3 ENSG00000240542 Keratin associated protein 9-1 17 41189887-41190639 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Not detected adipose tissue: 0.0 -L1TD1 ECAT11, FLJ10884 ENSG00000240563 LINE-1 type transposase domain containing 1 1 62194831-62212328 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA028501 Uncertain Tissue enhanced 0 placenta: 16.5;testis: 11.0 appendix: 6.4 -AQP1 CHIP28, CO ENSG00000240583 Aquaporin 1 (Colton blood group) 7 30911855-30925516 Blood group antigen proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001707, HPA019206 Supported Supported Plasma membrane Expressed in all kidney: 801.2 -C1QTNF9 AQL1, C1QTNF9A, CTRP9, MGC48915 ENSG00000240654 C1q and tumor necrosis factor related protein 9 13 24307166-24322535 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA056632 Uncertain Mixed skeletal muscle: 2.9 -ISY1 fSAP33, KIAA1160 ENSG00000240682 ISY1 splicing factor homolog 3 129127415-129161293 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA006312, HPA016995 Supported Validated Nuclear speckles Expressed in all lymph node: 37.0 -PNMA2 MA2, RGAG2 ENSG00000240694 Paraneoplastic Ma antigen 2 8 26504686-26514092 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001936 Supported Tissue enriched 12 cerebral cortex: 163.9 adrenal gland: 13.6 -LRRD1 IMAGE:4798971 ENSG00000240720 Leucine-rich repeats and death domain containing 1 7 92112159-92179531 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 38 testis: 30.8 epididymis: 0.8 -KRBOX1 ENSG00000240747 KRAB box domain containing 1 3 42809483-42942792 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046901 Approved Nucleoplasm
Golgi apparatus Tissue enriched 31 testis: 287.3 epididymis: 9.1 -PCDHGC5 PCDH-GAMMA-C5 ENSG00000240764 Protocadherin gamma subfamily C, 5 5 141489121-141512979 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008755, HPA051540 Uncertain Approved Nucleoplasm Tissue enriched 44 cerebral cortex: 50.8 smooth muscle: 1.1 -ARHGEF25 GEFT, p63RhoGEF ENSG00000240771 Rho guanine nucleotide exchange factor (GEF) 25 12 57610180-57619379 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052016 Uncertain Approved Vesicles Mixed endometrium: 111.5 -TMEM189 Kua ENSG00000240849 Transmembrane protein 189 20 50118254-50153734 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA059549 Approved Supported Endoplasmic reticulum Expressed in all smooth muscle: 31.1 -RDH14 PAN2, SDR7C4 ENSG00000240857 Retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 2 18554723-18560680 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056686 Approved Approved Nucleoplasm
Cytosol Expressed in all parathyroid gland: 31.3 -KRTAP4-7 KAP4.7 ENSG00000240871 Keratin associated protein 4-7 17 41084150-41106067 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -PLCXD2 FLJ31579 ENSG00000240891 Phosphatidylinositol-specific phospholipase C, X domain containing 2 3 111674676-111846447 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA055947 Uncertain Approved Nucleoplasm Mixed testis: 3.8 -MIF GIF, GLIF ENSG00000240972 Macrophage migration inhibitory factor (glycosylation-inhibiting factor) 22 23894004-23895227 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003868, CAB005284 Approved Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 40.6 -GVQW1 bA205M20.5, TIGD1L2 ENSG00000241043 GVQW motif containing 1 9 32566789-32568621 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA074576 Approved Mitochondria Mixed parathyroid gland: 2.5 -NSUN6 ARL5B-AS1, FLJ23743, NOPD1 ENSG00000241058 NOP2/Sun domain family, member 6 10 18545561-18659285 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045902 Approved Approved Golgi apparatus Expressed in all liver: 30.7 -HLA-DOB ENSG00000241106 Major histocompatibility complex, class II, DO beta 6 32812763-32817048 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013846 Approved Group enriched 5 lymph node: 19.9;spleen: 18.8;tonsil: 31.8;urinary bladder: 8.6 colon: 3.6 -UGT1A9 HLUGP4, LUGP4, UGT1AI ENSG00000241119 UDP glucuronosyltransferase 1 family, polypeptide A9 2 233671853-233773300 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 586 kidney: 461.7;liver: 93.2 cerebral cortex: 0.4 -KRTAP10-5 KAP10.5, KAP18.5, KRTAP18-5 ENSG00000241123 Keratin associated protein 10-5 21 44579455-44580604 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -YAE1D1 C7orf36, GK003 ENSG00000241127 Yae1 domain containing 1 7 39566376-39610320 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA019226, HPA031249 Uncertain Approved Cytosol Expressed in all testis: 34.3 -OR14A2 OR5AX1, OR5AX1P ENSG00000241128 Olfactory receptor, family 14, subfamily A, member 2 1 247723099-247724043 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA052685 Uncertain Tissue enriched 51 testis: 5.1 adipose tissue: 0.0 -TDGF1 CR, CRIPTO, Cripto-1 ENSG00000241186 Teratocarcinoma-derived growth factor 1 3 46574555-46626543 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 spleen: 30.5 kidney: 9.7 -KRTAP5-8 KRTAP5-2, KRTAP5.8, UHSKerB ENSG00000241233 Keratin associated protein 5-8 11 71538025-71539207 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 1.3 epididymis: 0.8 -KRTAP4-16P KAP4A, KRTAP4P1 ENSG00000241241 Keratin associated protein 4-16, pseudogene 17 41101502-41102209 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -CRCP CGRP-RCP, RCP, RCP9 ENSG00000241258 CGRP receptor component 7 66114604-66154568 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007216 Approved Approved Nuclear bodies Expressed in all parathyroid gland: 31.7 -CDRT1 FBXW10B, FBXW10P1, HREP, SM25H2 ENSG00000241322 CMT1A duplicated region transcript 1 17 15565483-15619704 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA013332, HPA047457 Approved Nucleus
Nucleoli Tissue enriched 5 testis: 27.0 esophagus: 5.3 -RPL36A L36A, RPL44 ENSG00000241343 Ribosomal protein L36a X 101390824-101396154 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA063979, HPA077586 Uncertain Supported Plasma membrane
Cytosol Expressed in all ovary: 3443.9 -PDXP CIN, dJ37E16.5, FLJ32703 ENSG00000241360 Pyridoxal (pyridoxine, vitamin B6) phosphatase 22 37658727-37666934 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA000531 Approved Tissue enhanced 0 cerebral cortex: 136.4 testis: 30.5 -RPP21 C6orf135, Em:AB014085.3, FLJ22638 ENSG00000241370 Ribonuclease P/MRP 21kDa subunit 6 30345131-30346884 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed skin: 16.1 -CD302 BIMLEC, CLEC13A, DCL-1, KIAA0022 ENSG00000241399 CD302 molecule 2 159768630-159798255 CD markers, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all liver: 98.7 -EGFL8 C6orf8, NG3 ENSG00000241404 EGF-like-domain, multiple 8 6 32164583-32168281 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061173 Uncertain Uncertain Nuclear speckles
Vesicles Mixed skin: 2.7 -ATP5J2 ATP5JL, F1Fo-ATPase ENSG00000241468 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 7 99448475-99466331 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067267, HPA070412 Approved Supported Nucleoplasm
Mitochondria Expressed in all skeletal muscle: 463.2 -SSX2 CT5.2a, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX ENSG00000241476 Synovial sarcoma, X breakpoint 2 X 52644567-52707189 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045683, CAB046020 Supported Tissue enriched 112 testis: 46.0 thyroid gland: 0.4 -ARHGAP8 BPGAP1, FLJ20185 ENSG00000241484 Rho GTPase activating protein 8 22 44752558-44862788 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA069694 Approved Nucleus Mixed epididymis: 13.9 -AF011889.5 ENSG00000241489 X 149482543-149533935 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Expressed in all epididymis: 64.5 -ARPC4 ARC20, p20-Arc ENSG00000241553 Actin related protein 2/3 complex, subunit 4, 20kDa 3 9792495-9807726 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all lymph node: 167.0 -CORT MGC32686 ENSG00000241563 Cortistatin 1 10449719-10451902 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 23 cerebral cortex: 24.9 placenta: 1.1 -KRTAP9-4 KAP9.4 ENSG00000241595 Keratin associated protein 9-4 17 41249687-41250653 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -KRTAP5-4 KRTAP5.4 ENSG00000241598 Keratin associated protein 5-4 11 1620958-1622138 Predicted intracellular proteins No evidence No evidence Not detected skeletal muscle: 0.1 -UGT1A1 GNT1, UGT1, UGT1A ENSG00000241635 UDP glucuronosyltransferase 1 family, polypeptide A1 2 233760248-233773299 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 33 duodenum: 205.0;liver: 155.7;small intestine: 83.9 kidney: 4.4 -INMT ENSG00000241644 Indolethylamine N-methyltransferase 7 30697985-30757602 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA061343 Approved Golgi apparatus
Vesicles Tissue enhanced 0 lung: 144.9 seminal vesicle: 65.5 -ARPC1A Arc40, SOP2Hs, SOP2L ENSG00000241685 Actin related protein 2/3 complex, subunit 1A, 41kDa 7 99325898-99388164 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004334 Approved Approved Cell Junctions
Cytosol Expressed in all thyroid gland: 131.0 -RP5-860F19.8 ENSG00000241690 20 2814968-2818066 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enriched 48 testis: 10.5 epididymis: 0.2 -TMEFF1 C9orf2, CT120.1, H7365 ENSG00000241697 Transmembrane protein with EGF-like and two follistatin-like domains 1 9 100473113-100577636 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051501 Uncertain Tissue enriched 5 cerebral cortex: 10.7 testis: 2.0 -SPRR2A ENSG00000241794 Small proline-rich protein 2A 1 153056113-153057537 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 8 esophagus: 5321.2 tonsil: 669.2 -ATP5O ATPO, OSCP ENSG00000241837 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 21 33903453-33915980 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016209, HPA041394 Supported Supported Mitochondria Expressed in all heart muscle: 518.0 -PLEKHO2 DKFZp761K2312, PLEKHQ1, PP1628, pp9099 ENSG00000241839 Pleckstrin homology domain containing, family O member 2 15 64841883-64868007 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040055 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all spleen: 121.4 -C8orf58 FLJ34715 ENSG00000241852 Chromosome 8 open reading frame 58 8 22599601-22604150 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA024667, HPA028286 Uncertain Approved Nuclear bodies Mixed testis: 28.1 -PISD dJ858B16.2, PSDC ENSG00000241878 Phosphatidylserine decarboxylase 22 31618491-31662432 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA031090, HPA031091 Approved Approved Golgi apparatus
Cytosol Expressed in all adipose tissue: 35.9 -HOGA1 C10orf65, DHDPS2, DHDPSL, FLJ37472, NPL2 ENSG00000241935 4-hydroxy-2-oxoglutarate aldolase 1 10 97584323-97612802 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039466 Approved Tissue enhanced 0 kidney: 53.2;liver: 20.7 adrenal gland: 8.2 -PWP2 EHOC-17, PWP2H, UTP1 ENSG00000241945 PWP2 periodic tryptophan protein homolog (yeast) 21 44107290-44131181 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA024573 Uncertain Supported Nucleoli
Cytosol Mixed skin: 5.4 -PI4KA PI4K-ALPHA, pi4K230, PIK4CA ENSG00000241973 Phosphatidylinositol 4-kinase, catalytic, alpha 22 20707691-20859417 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB009092, HPA075515 Approved Approved Nucleoplasm
Plasma membrane Expressed in all cerebral cortex: 114.0 -AKAP2 AKAP-KL, DKFZp564L0716, KIAA0920, PRKA2 ENSG00000241978 A kinase (PRKA) anchor protein 2 9 110048598-110172512 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all placenta: 122.9 -KIR3DL3 CD158z, KIR3DL7, KIR44, KIRC1 ENSG00000242019 Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 19 54724479-54736536 Predicted membrane proteins No evidence No evidence Not detected adipose tissue: 0.0 -HYPK C15orf63, FLJ20431, HSPC136 ENSG00000242028 Huntingtin interacting protein K 15 43796142-43803043 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055252 Uncertain Supported Nucleoplasm
Microtubules Mixed testis: 6.7 -AMACR RACE ENSG00000242110 Alpha-methylacyl-CoA racemase 5 33986178-34008108 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001809, HPA019527, HPA020912 Supported Supported Vesicles
Plasma membrane Expressed in all kidney: 134.0 -MTFP1 HSPC242, MTP18 ENSG00000242114 Mitochondrial fission process 1 22 30425530-30429053 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA077396 Approved Mitochondria Expressed in all epididymis: 18.7 -ARHGDIG RHOGDI-3 ENSG00000242173 Rho GDP dissociation inhibitor (GDI) gamma 16 268727-283010 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 131.5;duodenum: 45.5 small intestine: 18.2 -OR51B5 ENSG00000242180 Olfactory receptor, family 51, subfamily B, member 5 11 5342586-5343524 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA063124 Uncertain Not detected testis: 0.3 -TCP10L PRED77 ENSG00000242220 T-complex 10-like 21 32574841-32587373 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044709 Approved Tissue enriched 27 testis: 283.4 liver: 10.6 -PSG2 CEA, PSBG2, PSG1, PSGGB ENSG00000242221 Pregnancy specific beta-1-glycoprotein 2 19 43064211-43083045 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 229 placenta: 342.1 smooth muscle: 1.4 -ARFGAP3 ARFGAP1 ENSG00000242247 ADP-ribosylation factor GTPase activating protein 3 22 42796502-42858106 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000638 Approved Supported Golgi apparatus
Cytosol Expressed in all adrenal gland: 113.0 -BGLAP OCN ENSG00000242252 Bone gamma-carboxyglutamate (gla) protein 1 156241962-156243321 FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed skin: 2.1 -C22orf39 MGC74441 ENSG00000242259 Chromosome 22 open reading frame 39 22 19351368-19448232 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA073701 Approved Endoplasmic reticulum Expressed in all thyroid gland: 51.9 -PEG10 HB-1, KIAA1051, Mar2, Mart2, MEF3L, RGAG3 ENSG00000242265 Paternally expressed 10 7 94656325-94669695 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021324, HPA029915, HPA051038 Supported Validated Nucleus
Cytosol Group enriched 5 adrenal gland: 225.1;placenta: 659.4 ovary: 80.5 -CT47A2 CT47.2 ENSG00000242362 Cancer/testis antigen family 47, member A2 X 120977606-120980928 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 21 testis: 2.0 epididymis: 0.0 -UGT1A8 UGT1H ENSG00000242366 UDP glucuronosyltransferase 1 family, polypeptide A8 2 233617645-233773310 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 colon: 16.2;gallbladder: 10.4;rectum: 9.8;urinary bladder: 23.5 small intestine: 5.0 -EIF6 b(2)gcn, EIF3A, ITGB4BP, p27BBP ENSG00000242372 Eukaryotic translation initiation factor 6 20 35278907-35284985 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040873 Supported Supported Nucleoplasm Expressed in all esophagus: 173.9 -RBMY1E ENSG00000242389 RNA binding motif protein, Y-linked, family 1, member E Y 21880076-21918067 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA001534, HPA053147 Supported Tissue enriched 27 testis: 2.6 adipose tissue: 0.0 -PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 Protocadherin gamma subfamily C, 4 5 141484997-141512979 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008755, HPA078024 Uncertain Approved Golgi apparatus Tissue enriched 11 cerebral cortex: 16.4 adrenal gland: 1.4 -GTF2A1L ALF ENSG00000242441 General transcription factor IIA, 1-like 2 48617798-48733148 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 65 testis: 104.8 gallbladder: 1.6 -MRPL20 FLJ10024 ENSG00000242485 Mitochondrial ribosomal protein L20 1 1401908-1407313 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047074 Supported Supported Mitochondria Expressed in all epididymis: 155.4 -ARPIN C15orf38, MGC61550 ENSG00000242498 Actin-related protein 2/3 complex inhibitor 15 89895006-89912956 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040513, HPA047173, HPA052278 Uncertain Mixed parathyroid gland: 30.9 -UGT1A10 UGT1J ENSG00000242515 UDP glucuronosyltransferase 1 family, polypeptide A10 2 233636454-233773305 Cancer-related genes, Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 colon: 50.4;duodenum: 83.1;small intestine: 60.3 rectum: 40.2 -SERPINB10 bomapin, PI10 ENSG00000242550 Serpin peptidase inhibitor, clade B (ovalbumin), member 10 18 63897174-63936111 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015480, HPA043595, HPA059582 Uncertain Approved Nucleus
Cytosol Tissue enriched 32 bone marrow: 50.2 skin: 1.5 -HLA-DMB D6S221E, RING7 ENSG00000242574 Major histocompatibility complex, class II, DM beta 6 32934629-32941070 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012298 Supported Tissue enhanced 0 thyroid gland: 29.3 spleen: 12.0 -DECR2 PDCR, SDR17C1 ENSG00000242612 2,4-dienoyl CoA reductase 2, peroxisomal 16 401826-412487 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047631 Approved Peroxisomes Mixed duodenum: 10.8 -GNG10 ENSG00000242616 Guanine nucleotide binding protein (G protein), gamma 10 9 111661335-111670246 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all appendix: 92.5 -CNTF HCNTF ENSG00000242689 Ciliary neurotrophic factor 11 58622673-58625733 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019654 Uncertain Approved Vesicles Tissue enhanced 0 fallopian tube: 7.6 bone marrow: 4.3 -CCDC169 C13orf38, LOC728591, RP11-251J8.1 ENSG00000242715 Coiled-coil domain containing 169 13 36222008-36297840 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 15 testis: 78.1 parathyroid gland: 5.0 -RGAG4 KIAA2001, Mar5, Mart5 ENSG00000242732 Retrotransposon gag domain containing 4 X 72127110-72131901 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003652 Approved Approved Nucleoplasm Mixed thyroid gland: 4.1 -AP5Z1 KIAA0415, SPG48, zeta ENSG00000242802 Adaptor-related protein complex 5, zeta 1 subunit 7 4775622-4794312 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035693 Supported Supported Nucleoplasm
Nuclear speckles Mixed spleen: 15.7 -ZNF709 FLJ38281 ENSG00000242852 Zinc finger protein 709 19 12461184-12513854 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045573, HPA053153 Uncertain Approved Nucleoplasm Tissue enhanced 0 testis: 13.9 thyroid gland: 4.8 -STRC DFNB16 ENSG00000242866 Stereocilin 15 43599398-43618800 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015731 Uncertain Tissue enhanced 0 cerebral cortex: 1.4;epididymis: 1.5;testis: 1.7 skin: 0.8 -RBMY1B ENSG00000242875 RNA binding motif protein, Y-linked, family 1, member B Y 21511338-21549094 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA001534, HPA053147 Supported Tissue enriched 28 testis: 2.8 adipose tissue: 0.0 -ERVW-1 ERVWE1, HERV-7q, HERV-W, HERV-W-ENV, HERVW ENSG00000242950 Endogenous retrovirus group W, member 1 7 92468380-92477986 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 placenta: 77.1 testis: 6.7 -EIF4EBP3 4E-BP3 ENSG00000243056 Eukaryotic translation initiation factor 4E binding protein 3 5 140547666-140549578 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045537 Uncertain Expressed in all fallopian tube: 59.5 -PRAMEF4 RP5-845O24.6 ENSG00000243073 PRAME family member 4 1 12879224-12886201 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -PSG11 MGC22484, PSG13, PSG14 ENSG00000243130 Pregnancy specific beta-1-glycoprotein 11 19 43007656-43026512 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA042240, HPA046327 Supported Tissue enriched 78 placenta: 73.9 smooth muscle: 0.9 -UGT1A3 UGT1C ENSG00000243135 UDP glucuronosyltransferase 1 family, polypeptide A3 2 233729108-233773299 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 liver: 38.1 small intestine: 5.7 -PSG4 ENSG00000243137 Pregnancy specific beta-1-glycoprotein 4 19 43192702-43207299 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA046327 Approved Group enriched 8 parathyroid gland: 240.2;placenta: 192.9 colon: 28.5 -MRPL33 C2orf1, RPL33L ENSG00000243147 Mitochondrial ribosomal protein L33 2 27771717-27988087 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA066872 Approved Expressed in all adrenal gland: 589.1 -MICAL3 KIAA0819 ENSG00000243156 Microtubule associated monooxygenase, calponin and LIM domain containing 3 22 17787649-18024559 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000639, HPA003421, HPA034882 Uncertain Validated Nucleoplasm
Plasma membrane
Cytosol Expressed in all parathyroid gland: 69.7 -PPAN-P2RY11 ENSG00000243207 PPAN-P2RY11 readthrough 19 10106223-10114780 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level HPA014232 Uncertain Mixed fallopian tube: 2.4 -PCDHAC2 PCDH-ALPHA-C2 ENSG00000243232 Protocadherin alpha subfamily C, 2 5 140966235-141012344 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA076190 Approved Nucleoplasm
Mitochondria Tissue enriched 6 parathyroid gland: 90.7 cerebral cortex: 14.2 -STON1 SBLF, stoned-b1 ENSG00000243244 Stonin 1 2 48529383-48598513 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA005715 Uncertain Mixed smooth muscle: 37.0 -PGBD3 FLJ90201 ENSG00000243251 PiggyBac transposable element derived 3 10 49515105-49524227 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA025825 Uncertain Mixed parathyroid gland: 2.3 -PRAF2 JM4 ENSG00000243279 PRA1 domain family, member 2 X 49071156-49074071 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002859, HPA005504, CAB011655 Supported Approved Endoplasmic reticulum
Vesicles Expressed in all epididymis: 181.8 -VSIG8 ENSG00000243284 V-set and immunoglobulin domain containing 8 1 159854316-159862657 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA023219 Uncertain Tissue enhanced 0 skin: 13.6;tonsil: 6.1 fallopian tube: 2.1 -C7orf73 PL-5283 ENSG00000243317 Chromosome 7 open reading frame 73 7 135662496-135693418 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065565 Approved Mitochondria Expressed in all thyroid gland: 53.2 -KCTD7 CLN14, EPM3, FLJ32069 ENSG00000243335 Potassium channel tetramerization domain containing 7 7 66628881-66811187 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed testis: 27.5 -EFNA4 EPLG4, LERK4 ENSG00000243364 Ephrin-A4 1 155063731-155069553 Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB021350, HPA064952 Approved Uncertain Nucleus
Vesicles Mixed skin: 24.5 -TICAM2 TICAM-2, TIRP, TRAM ENSG00000243414 Toll-like receptor adaptor molecule 2 5 115578650-115602479 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed cervix: 6.4 -AF165138.7 ENSG00000243440 21 14591930-14658821 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA046639 Uncertain Not detected appendix: 0.7 -PALM2 ENSG00000243444 Paralemmin 2 9 109640788-109946703 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA074153 Approved Plasma membrane Tissue enhanced 0 cerebral cortex: 9.8 liver: 3.5 -C4orf48 ENSG00000243449 Chromosome 4 open reading frame 48 4 2041993-2043970 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA052447 Uncertain Supported Cytosol Tissue enhanced 0 cerebral cortex: 22.2 testis: 11.3 -NAT6 FUS2 ENSG00000243477 N-acetyltransferase 6 (GCN5-related) 3 50296402-50299421 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA039576 Approved Expressed in all testis: 45.8 -AMY2A AMY2 ENSG00000243480 Amylase, alpha 2A (pancreatic) 1 103616811-103625780 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045394, HPA045399, CAB045960, HPA046980 Supported Tissue enriched 313 pancreas: 31311.3 ovary: 100.1 -KRTAP10-11 KAP10.11, KAP18.11, KRTAP18-11, KRTAP18.11 ENSG00000243489 Keratin associated protein 10-11 21 44646414-44647650 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected adipose tissue: 0.0 -TNFRSF6B DcR3, M68, TR6 ENSG00000243509 Tumor necrosis factor receptor superfamily, member 6b, decoy 20 63696668-63698684 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047154 Uncertain Tissue enriched 6 appendix: 19.6 tonsil: 3.2 -WFDC6 C20orf171, dJ461P17.11, WAP6 ENSG00000243543 WAP four-disulfide core domain 6 20 45534196-45539495 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 16 epididymis: 317.8;testis: 83.3 fallopian tube: 12.4 -UPK3B FLJ32198, MGC10902, p35, UPIIIb ENSG00000243566 Uroplakin 3B 7 76510428-76516521 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA010506 Approved Approved Nucleus
Vesicles
Cytosol Group enriched 10 esophagus: 12.4;lung: 29.9;urinary bladder: 11.4 tonsil: 1.7 -AP000322.53 ENSG00000243627 21 34418715-34423966 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA029085 Uncertain Group enriched 6 breast: 3.3;fallopian tube: 3.2;kidney: 8.7 epididymis: 0.9 -IL10RB CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2 ENSG00000243646 Interleukin 10 receptor, beta 21 33266358-33297234 CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB020670, HPA047550 Approved Approved Cytosol Expressed in all placenta: 89.0 -CFB BF, BFD, H2-Bf ENSG00000243649 Complement factor B 6 31945650-31952084 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000951, HPA001817, HPA001832, CAB016381 Supported Uncertain Vesicles
Cell Junctions Tissue enriched 20 liver: 283.0 stomach: 13.9 -ZNF487 KRBO1, ZNF487P ENSG00000243660 Zinc finger protein 487 10 43436841-43483179 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level No evidence HPA037820 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Tissue enriched 5 testis: 51.1 fallopian tube: 9.8 -WDR92 FLJ31741, Monad ENSG00000243667 WD repeat domain 92 2 68122936-68157560 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035335, HPA035336 Approved Approved Nucleoplasm Mixed epididymis: 19.8 -NME2 NDPKB, NM23-H2 ENSG00000243678 NME/NM23 nucleoside diphosphate kinase 2 17 51165435-51171747 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA041113 Approved Expressed in all breast: 509.0 -PLA2G4B cPLA2-beta, HsT16992 ENSG00000243708 Phospholipase A2, group IVB (cytosolic) 15 41837775-41848147 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected bone marrow: 0.7 -LEFTY1 LEFTB, LEFTYB ENSG00000243709 Left-right determination factor 1 1 225886282-225911382 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA047883, HPA056210 Approved Tissue enhanced 0 colon: 59.7;rectum: 35.8 pancreas: 20.4 -CFAP57 FLJ32000, WDR65 ENSG00000243710 Cilia and flagella associated protein 57 1 43172149-43254358 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA002736, HPA028623 Supported Uncertain Cytosol Group enriched 8 fallopian tube: 35.3;testis: 27.6 liver: 3.8 -NPIPB5 ENSG00000243716 Nuclear pore complex interacting protein family, member B5 16 22479121-22536521 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA053611 Approved Approved Nucleoplasm Expressed in all skin: 271.1 -TTC4 FLJ41930, MGC5097 ENSG00000243725 Tetratricopeptide repeat domain 4 1 54715822-54742657 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041608, HPA042459 Approved Uncertain Nuclear speckles
Cytoplasmic bodies Expressed in all cervix: 13.2 -OR5V1 hs6M1-21 ENSG00000243729 Olfactory receptor, family 5, subfamily V, member 1 6 29355230-29431967 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA046707 Uncertain Not detected adipose tissue: 0.0 -ZMYM6NB ENSG00000243749 ZMYM6 neighbor 1 34981535-34985353 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA051024 Uncertain Approved Nucleus
Nucleoli Expressed in all placenta: 90.9 -KIR2DL3 CD158B2, cl-6, nkat2, nkat2a, nkat2b, p58 ENSG00000243772 Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 19 54738515-54753052 CD markers, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected spleen: 0.1 -JMJD7 ENSG00000243789 Jumonji domain containing 7 15 41828085-41837581 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005726 Uncertain Approved Cytosol Expressed in all skin: 28.0 -APOBEC3D APOBEC3DE, APOBEC3E, ARP6 ENSG00000243811 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D 22 39014363-39033276 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055116 Uncertain Mixed lymph node: 20.9 -OR2A7 HSDJ0798C17 ENSG00000243896 Olfactory receptor, family 2, subfamily A, member 7 7 144258607-144259722 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058272 Uncertain Mixed thyroid gland: 20.0 -TUBA4B FLJ13940, TUBA4 ENSG00000243910 Tubulin, alpha 4b 2 219253243-219272188 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 14 fallopian tube: 63.4 lung: 4.5 -MRPS6 C21orf101, MRP-S6, RPMS6 ENSG00000243927 Mitochondrial ribosomal protein S6 21 34073224-34143034 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007861, HPA008163, HPA049676 Supported Supported Mitochondria Expressed in all thyroid gland: 120.5 -ZNF512 KIAA1805 ENSG00000243943 Zinc finger protein 512 2 27582969-27623215 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031430 Approved Validated Nucleus Expressed in all parathyroid gland: 44.9 -GSTA1 ENSG00000243955 Glutathione S-transferase alpha 1 6 52791664-52803910 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004342, HPA048934, HPA053817 Supported Supported Cytosol Tissue enhanced 0 adrenal gland: 1142.9;kidney: 1300.7;liver: 1750.1 small intestine: 1023.4 -RGAG1 KIAA1318, Mar9, Mart9 ENSG00000243978 Retrotransposon gag domain containing 1 X 110358816-110456334 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA001242 Uncertain Tissue enriched 19 testis: 19.4 placenta: 1.0 -ACY1 ENSG00000243989 Aminoacylase 1 3 51983340-51989197 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003695, HPA036174, HPA036175 Supported Group enriched 6 duodenum: 182.6;kidney: 462.6;liver: 146.9;small intestine: 158.4 thyroid gland: 40.0 -NFS1 IscS, NifS ENSG00000244005 NFS1 cysteine desulfurase 20 35668055-35699359 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034314, HPA051801, HPA054755 Supported Supported Nucleoplasm
Cytosol Expressed in all kidney: 43.4 -MT1HL1 MT1P2 ENSG00000244020 Metallothionein 1H-like 1 1 237004103-237004418 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 7 heart muscle: 2.7 urinary bladder: 0.3 -KRTAP19-3 KAP19.3 ENSG00000244025 Keratin associated protein 19-3 21 30480048-30491985 Predicted intracellular proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -DDOST KIAA0115, OST, OST48, WBP1 ENSG00000244038 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 1 20651767-20661544 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009746, HPA046841, HPA052867 Supported Supported Endoplasmic reticulum Expressed in all thyroid gland: 307.5 -TMEM199 C17orf32, MGC45714 ENSG00000244045 Transmembrane protein 199 17 28357581-28363683 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027051 Uncertain Expressed in all parathyroid gland: 19.1 -LCE3C LEP15, SPRL3A ENSG00000244057 Late cornified envelope 3C 1 152511535-152601086 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 tonsil: 23.4 skin: 2.1 -GSTA2 GST2 ENSG00000244067 Glutathione S-transferase alpha 2 6 52750089-52763569 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004342, HPA048934, HPA053817 Supported Supported Cytosol Group enriched 5 kidney: 646.8;liver: 983.1 gallbladder: 156.1 -SPRR2F ENSG00000244094 Small proline-rich protein 2F 1 153112114-153113515 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Group enriched 9 esophagus: 167.8;ovary: 83.4;tonsil: 65.2 testis: 11.7 -DNAJC25-GNG10 ENSG00000244115 DNAJC25-GNG10 readthrough 9 111631386-111670229 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Mixed prostate: 28.5 -UGT1A7 UGT1G ENSG00000244122 UDP glucuronosyltransferase 1 family, polypeptide A7 2 233681938-233773299 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 13 esophagus: 61.6 tonsil: 4.9 -P2RY11 P2Y11 ENSG00000244165 Purinergic receptor P2Y, G-protein coupled, 11 19 10111538-10115372 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA014232 Approved Mixed lymph node: 7.3 -TMEM141 MGC14141 ENSG00000244187 Transmembrane protein 141 9 136791355-136793257 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014615, HPA050244 Approved Supported Cell Junctions
Mitochondria Expressed in all prostate: 214.3 -IFITM10 ENSG00000244242 Interferon induced transmembrane protein 10 11 1732410-1750591 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adrenal gland: 12.7;cerebral cortex: 12.0 seminal vesicle: 4.0 -XXbac-BPG116M5.17 ENSG00000244255 6 31927698-31952048 Predicted secreted proteins Evidence at protein level Evidence at protein level HPA000951, HPA001817, HPA001832 Approved Tissue enhanced 0 liver: 3.3;lung: 2.9 spleen: 1.2 -DBNDD2 C20orf35, HSMNP1 ENSG00000244274 Dysbindin (dystrobrevin binding protein 1) domain containing 2 20 45406057-45410610 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043991 Supported Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 461.5 -LY6G6D C6orf23, G6D, Ly6-D, MEGT1, NG25 ENSG00000244355 Lymphocyte antigen 6 complex, locus G6D 6 31715356-31717804 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA054412 Uncertain Tissue enhanced 0 seminal vesicle: 2.0 prostate: 0.9 -KRTAP19-7 KAP19.7 ENSG00000244362 Keratin associated protein 19-7 21 30541660-30561314 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -RBMY1D ENSG00000244395 RNA binding motif protein, Y-linked, family 1, member D Y 21880076-21894526 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA001534, HPA053147 Supported Not detected adipose tissue: 0.0 -ETV5 ERM ENSG00000244405 Ets variant 5 3 186046308-186110318 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009590, HPA063065 Approved Supported Nucleoplasm Tissue enhanced 0 parathyroid gland: 112.2 cerebral cortex: 74.9 -KRTAP5-7 KRTAP5-3, KRTAP5.7 ENSG00000244411 Keratin associated protein 5-7 11 71527267-71528674 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 1.8 epididymis: 0.8 -CFHR1 CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2 ENSG00000244414 Complement factor H-related 1 1 196819757-196832189 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038915, HPA038922, HPA040726 Supported Approved Vesicles Tissue enriched 144 liver: 1055.2 lymph node: 7.3 -RBM12 HRIHFB2091, KIAA0765, SWAN ENSG00000244462 RNA binding motif protein 12 20 35648925-35664956 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043258, HPA043621 Approved Validated Nucleoplasm Expressed in all lymph node: 47.9 -UGT1A4 HUG-BR2, UGT1D ENSG00000244474 UDP glucuronosyltransferase 1 family, polypeptide A4 2 233718778-233773299 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 31 liver: 212.1 duodenum: 6.9 -ERVFRD-1 envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2 ENSG00000244476 Endogenous retrovirus group FRD, member 1 6 11102489-11111732 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 31 parathyroid gland: 29.8;placenta: 51.4 epididymis: 1.3 -LILRA6 CD85b, ILT8, LILRB6 ENSG00000244482 Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 19 54236592-54242791 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 appendix: 7.7;smooth muscle: 3.3 spleen: 2.9 -SCARF2 HUMZD58C02, SREC-II, SREC2 ENSG00000244486 Scavenger receptor class F, member 2 22 20424585-20437859 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035079 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Mixed spleen: 6.0 -APOBEC3C APOBEC1L, ARDC2, ARDC4, ARP5, bK150C2.3, PBI ENSG00000244509 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 22 39014083-39020352 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB033048, HPA071523 Approved Approved Intermediate filaments Mixed fallopian tube: 84.0 -KRTAP4-2 KAP4.2 ENSG00000244537 Keratin associated protein 4-2 17 41177446-41178208 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -RAD21L1 dJ545L17.2, RAD21L ENSG00000244588 RAD21 cohesin complex component like 1 20 1226056-1296421 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA053282 Uncertain Tissue enriched 78 testis: 21.5 seminal vesicle: 0.2 -CCDC13 FLJ25467 ENSG00000244607 Coiled-coil domain containing 13 3 42692663-42773253 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047429 Approved Supported Centrosome Tissue enhanced 0 fallopian tube: 7.5;testis: 6.9 cerebral cortex: 1.5 -ASPRV1 FLJ25084, SASPase, Taps ENSG00000244617 Aspartic peptidase, retroviral-like 1 2 69960089-69962265 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA034809, HPA034810 Supported Tissue enriched 13 skin: 286.7 breast: 22.3 -OR2AE1 OR2AE2 ENSG00000244623 Olfactory receptor, family 2, subfamily AE, member 1 7 99875987-99877057 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA042957 Uncertain Not detected parathyroid gland: 0.2 -KRTAP20-1 KAP20.1 ENSG00000244624 Keratin associated protein 20-1 21 30616425-30616699 Predicted intracellular proteins No evidence No evidence No evidence Not detected testis: 0.1 -UBE2V1 CROC-1, CROC1, UBE2V, UEV-1, UEV1A ENSG00000244687 Ubiquitin-conjugating enzyme E2 variant 1 20 50081124-50115959 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052535, HPA053186 Validated Nucleoplasm Expressed in all cerebral cortex: 110.0 -CTAGE8 ENSG00000244693 CTAGE family, member 8 7 144266701-144269288 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA000387, HPA000922 Uncertain Mixed thyroid gland: 12.5 -PTCHD4 C6orf138, dJ402H5.2, FLJ41841 ENSG00000244694 Patched domain containing 4 6 47878028-48068689 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA041276 Uncertain Approved Plasma membrane
Cytosol Mixed seminal vesicle: 2.8 -C4A C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG ENSG00000244731 Complement component 4A (Rodgers blood group) 6 31982024-32002681 Blood group antigen proteins, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB009811, CAB032603, HPA046356, HPA048287, HPA050103 Approved Tissue enhanced 0 liver: 46.2 thyroid gland: 28.2 -HBB beta-globin, CD113t-C, HBD ENSG00000244734 Hemoglobin, beta 11 5225464-5229395 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009526, HPA043234 Supported Tissue enriched 9 bone marrow: 78261.0 placenta: 8978.3 -CRYBB2 CCA2, CRYB2, CRYB2A ENSG00000244752 Crystallin, beta B2 22 25219522-25231869 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043749 Supported Approved Nucleoplasm Tissue enhanced 0 testis: 1.5 epididymis: 0.4 -N4BP2L2 CG005, PFAAP5 ENSG00000244754 NEDD4 binding protein 2-like 2 13 32432417-32538885 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA039338, HPA039434, HPA059327 Approved Approved Nucleoplasm Expressed in all endometrium: 57.2 -ZNF585B FLJ14928, SZFP41 ENSG00000245680 Zinc finger protein 585B 19 37181579-37218153 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA075556 Approved Nucleoplasm
Cytoplasmic bodies Mixed parathyroid gland: 19.6 -CEBPA C/EBP-alpha, CEBP ENSG00000245848 CCAAT/enhancer binding protein (C/EBP), alpha 19 33299934-33302564 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA052734, HPA065037, HPA067937 Approved Approved Nucleoplasm
Vesicles Expressed in all adipose tissue: 107.9 -H2AFJ FLJ10903, MGC921 ENSG00000246705 H2A histone family, member J 12 14774383-14778002 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Expressed in all testis: 335.4 -UBAP1L ENSG00000246922 Ubiquitin associated protein 1-like 15 65092770-65115197 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA065334, HPA067923 Uncertain Uncertain Nuclear bodies Mixed cerebral cortex: 1.8 -PGAM5 BXLBv68, MGC5352 ENSG00000247077 PGAM family member 5, serine/threonine protein phosphatase, mitochondrial 12 132710819-132722734 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036978, HPA036979, CAB068215 Supported Supported Mitochondria Expressed in all testis: 28.3 -ZCCHC3 C20orf99, dJ1103G7.7 ENSG00000247315 Zinc finger, CCHC domain containing 3 20 296968-300321 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042972 Approved Vesicles Expressed in all placenta: 23.0 -SPTY2D1-AS1 ENSG00000247595 SPTY2D1 antisense RNA 1 11 18599787-18610255 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enriched 14 testis: 421.2 skin: 29.4 -TWF2 A6r, A6RP, PTK9L ENSG00000247596 Twinfilin actin binding protein 2 3 52228610-52239260 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA053874 Uncertain Supported Plasma membrane Expressed in all lymph node: 62.1 -MARS2 mtMetRS, SPAX3 ENSG00000247626 Methionyl-tRNA synthetase 2, mitochondrial 2 197705369-197708387 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035589, HPA035590 Uncertain Approved Intermediate filaments
Cytosol Expressed in all lymph node: 7.6 -USP51 ENSG00000247746 Ubiquitin specific peptidase 51 X 55484616-55489202 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA001942 Uncertain Tissue enriched 7 epididymis: 60.9 parathyroid gland: 9.0 -BCKDHA MSU, OVD1A ENSG00000248098 Branched chain keto acid dehydrogenase E1, alpha polypeptide 19 41397460-41431345 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036640 Supported Expressed in all thyroid gland: 56.6 -INSL3 MGC119818, MGC119819, RLF, RLNL ENSG00000248099 Insulin-like 3 (Leydig cell) 19 17816512-17821574 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028615 Supported Tissue enriched 116 testis: 772.9 appendix: 6.6 -ADH1C ADH3 ENSG00000248144 Alcohol dehydrogenase 1C (class I), gamma polypeptide 4 99336492-99353027 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047814, HPA060902 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 duodenum: 522.4;liver: 886.9;stomach: 478.6 colon: 281.0 -TRIM39-RPP21 ENSG00000248167 TRIM39-RPP21 readthrough 6 30328907-30346854 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA051120 Uncertain Supported Cytosol Not detected testis: 0.2 -AC037459.4 ENSG00000248235 8 22589274-22602084 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA024667 Uncertain Tissue enhanced 0 spleen: 3.7 small intestine: 2.0 -APELA ELA, Ende, tdl ENSG00000248329 Apelin receptor early endogenous ligand 4 164877004-164898965 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 prostate: 6.6 kidney: 2.1 -CDK11B CDC2L1, CDK11-p110, CDK11-p46, CDK11-p58 ENSG00000248333 Cyclin-dependent kinase 11B 1 1635227-1659012 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA025061, HPA073626 Approved Approved Nuclear speckles Expressed in all testis: 46.8 -PCDHAC1 ENSG00000248383 Protocadherin alpha subfamily C, 1 5 140926369-141012344 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052775 Approved Nucleus
Nucleoli
Vesicles Tissue enriched 26 parathyroid gland: 68.4 cerebral cortex: 2.6 -TARM1 ENSG00000248385 T cell-interacting, activating receptor on myeloid cells 1 19 54069895-54081365 Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA051022, HPA054401 Uncertain Not detected spleen: 0.2 -PRR5-ARHGAP8 ENSG00000248405 PRR5-ARHGAP8 readthrough 22 44702233-44862706 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed spleen: 1.3 -POU5F2 FLJ25680, SPRM-1 ENSG00000248483 POU domain class 5, transcription factor 2 5 93734806-93741637 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 158 testis: 15.7 adipose tissue: 0.0 -PCP4L1 IQM1 ENSG00000248485 Purkinje cell protein 4 like 1 1 161258727-161285450 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA052833 Approved Nucleoplasm
Mitochondria Tissue enhanced 0 cerebral cortex: 45.4;urinary bladder: 41.0 seminal vesicle: 22.8 -ABHD14A DKFZP564O243, DORZ1 ENSG00000248487 Abhydrolase domain containing 14A 3 51971426-51981199 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA038153, HPA038154, HPA056913 Approved Supported Vesicles Expressed in all thyroid gland: 50.8 -TMEM110-MUSTN1 ENSG00000248592 TMEM110-MUSTN1 readthrough 3 52833121-52897562 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA051855 Uncertain Approved Cytosol Tissue enhanced 0 skeletal muscle: 11.1 adipose tissue: 6.6 -RBM14-RBM4 ENSG00000248643 RBM14-RBM4 readthrough 11 66616626-66646469 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA047849 Uncertain Approved Nucleoplasm
Cytosol Not detected epididymis: 0.9 -LY75-CD302 ENSG00000248672 LY75-CD302 readthrough 2 159771851-159904710 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA049108 Uncertain Mixed appendix: 2.6 -CCDC153 LOC283152 ENSG00000248712 Coiled-coil domain containing 153 11 119189638-119196769 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA041497 Uncertain Uncertain Cytosol Tissue enhanced 0 fallopian tube: 18.4 parathyroid gland: 4.3 -RP11-766F14.2 ENSG00000248713 4 99636529-99654648 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 26 skeletal muscle: 24.6 kidney: 0.9 -ACTN3 ENSG00000248746 Actinin, alpha 3 (gene/pseudogene) 11 66546395-66563329 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA006035 Uncertain Tissue enriched 119 skeletal muscle: 556.7 testis: 4.6 -RP1-130H16.18 ENSG00000248751 22 30285238-30299482 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 1.2 testis: 1.0 -TNFSF12-TNFSF13 TWE-PRIL ENSG00000248871 TNFSF12-TNFSF13 readthrough 17 7549099-7561601 Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA004863, HPA052967 Uncertain Mixed adipose tissue: 1.9 -FMN1 DKFZP686C2281, FLJ45135, FMN, LD, MGC125288, MGC125289 ENSG00000248905 Formin 1 15 32765545-33194733 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA005465, HPA046786 Approved Supported Nucleoplasm
Cytosol Tissue enhanced 0 testis: 8.1 cervix: 4.2 -ATP5J2-PTCD1 ENSG00000248919 ATP5J2-PTCD1 readthrough 7 99419749-99466197 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA020106, HPA047679 Uncertain Approved Mitochondria Mixed cerebral cortex: 5.6 -USP17L19 ENSG00000248920 Ubiquitin specific peptidase 17-like family member 19 4 9253378-9255329 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -USP17L22 ENSG00000248933 Ubiquitin specific peptidase 17-like family member 22 4 9267619-9269570 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected epididymis: 0.2 -XXbac-BPG181M17.5 ENSG00000248993 6 32937364-32953122 Predicted secreted proteins Evidence at protein level Evidence at protein level HPA012298 Uncertain Not detected small intestine: 0.4 -USP17L17 ENSG00000249104 Ubiquitin specific peptidase 17-like family member 17 4 9243879-9245830 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -HAUS5 dgt5, KIAA0841 ENSG00000249115 HAUS augmin-like complex, subunit 5 19 35612744-35625349 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067250 Approved Mixed lymph node: 7.2 -EPPIN-WFDC6 SPINLW1-WFDC6 ENSG00000249139 EPPIN-WFDC6 readthrough 20 45536986-45547426 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 79 epididymis: 40.7;testis: 57.7 fallopian tube: 0.6 -RP11-514O12.4 ENSG00000249141 6 166858094-166956124 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed epididymis: 2.5 -PCDHA11 CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11 ENSG00000249158 Protocadherin alpha 11 5 140868183-141012344 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA077160 Approved Vesicles
Cell Junctions Tissue enhanced 0 cerebral cortex: 7.6;parathyroid gland: 4.7 testis: 2.3 -AP000304.12 ENSG00000249209 21 33584687-33931607 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA039558 Uncertain Mixed placenta: 1.7 -ATP5L2 ATP5K2, dJ222E13.5 ENSG00000249222 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2 22 42639803-42640601 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA044629 Uncertain Supported Mitochondria Mixed epididymis: 1.1 -AC069368.3 ENSG00000249240 15 64841883-64930920 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 spleen: 9.0 appendix: 6.3 -TMEM150C FLJ12993 ENSG00000249242 Transmembrane protein 150C 4 82483170-82562357 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA052921 Supported Tissue enhanced 0 epididymis: 179.7 ovary: 43.5 -AC068533.7 ENSG00000249319 7 66087761-66152277 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed parathyroid gland: 7.9 -CFAP99 ENSG00000249428 Cilia and flagella associated protein 99 4 2426476-2462926 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Group enriched 10 fallopian tube: 3.6;testis: 7.4 lung: 0.5 -NAIP BIRC1, NLRB1 ENSG00000249437 NLR family, apoptosis inhibitory protein 5 70968483-71025114 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042438 Approved Mixed spleen: 3.9 -ZNF286B ZNF286C, ZNF286L, ZNF590 ENSG00000249459 Zinc finger protein 286B 17 18658429-18682262 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA068125 Uncertain Approved Nuclear speckles
Cytosol Mixed ovary: 2.7 -ZNF324B FLJ45850 ENSG00000249471 Zinc finger protein 324B 19 58451604-58457833 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA023400 Uncertain Approved Nucleoli
Cytosol Mixed spleen: 4.8 -SPATS1 FLJ25442, SPATA8, SRSP1 ENSG00000249481 Spermatogenesis associated, serine-rich 1 6 44342660-44377167 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA030897, HPA046230, HPA049722 Approved Approved Nucleoplasm Group enriched 6 fallopian tube: 13.9;testis: 45.0 epididymis: 4.9 -CLRN2 ENSG00000249581 Clarin 2 4 17515165-17527104 Predicted membrane proteins, Transporters Evidence at transcript level No evidence Evidence at transcript level HPA042407 Uncertain Not detected testis: 0.3 -RP4-539M6.19 ENSG00000249590 22 30409255-30428990 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Mixed duodenum: 3.7 -AP000295.9 ENSG00000249624 21 33246774-33283212 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed lung: 1.5 -THEGL ENSG00000249693 Theg spermatid protein-like 4 56530609-56603507 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA068093 Uncertain Tissue enriched 7 testis: 5.6 smooth muscle: 0.8 -ZNF564 MGC26914 ENSG00000249709 Zinc finger protein 564 19 12525370-12551542 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA043998 Uncertain Approved Golgi apparatus Mixed thyroid gland: 10.5 -FER1L5 DKFZp434I0121 ENSG00000249715 Fer-1-like family member 5 2 96642737-96704887 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 14 testis: 7.5 seminal vesicle: 0.5 -ECSCR ARIA, ECSM2 ENSG00000249751 Endothelial cell surface expressed chemotaxis and apoptosis regulator 5 139448556-139462743 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed placenta: 95.8 -RP11-15K19.2 ENSG00000249773 7 55887277-55955239 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA047159 Uncertain Tissue enhanced 0 testis: 3.2 endometrium: 1.2 -USP17L21 ENSG00000249811 Ubiquitin specific peptidase 17-like family member 21 4 9262872-9264823 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -HS3ST5 3-OST-5 ENSG00000249853 Heparan sulfate (glucosamine) 3-O-sulfotransferase 5 6 114055586-114343045 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021823, HPA064677 Approved Group enriched 5 cerebral cortex: 6.2;seminal vesicle: 2.2;skeletal muscle: 1.3 adrenal gland: 0.6 -MTRNR2L5 ENSG00000249860 MT-RNR2-like 5 10 55599303-55600041 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected skeletal muscle: 0.3 -LGALS16 ENSG00000249861 Lectin, galactoside-binding, soluble, 16 19 39655894-39660647 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 53 placenta: 7.6 testis: 0.1 -RNF103-CHMP3 RNF103-VPS24 ENSG00000249884 RNF103-CHMP3 readthrough 2 86505668-86721122 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA015673 Uncertain Tissue enhanced 0 cerebral cortex: 4.2 bone marrow: 2.7 -PDCD6 ALG-2, PEF1B ENSG00000249915 Programmed cell death 6 5 271621-353856 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047221 Approved Cytosol Expressed in all epididymis: 120.0 -GOLGA8K ENSG00000249931 Golgin A8 family, member K 15 32392782-32403292 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 8 testis: 8.2 thyroid gland: 1.0 -CCDC79 FLJ35894 ENSG00000249961 Coiled-coil domain containing 79 16 66754976-66801620 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 22 testis: 25.1 bone marrow: 1.1 -RP11-548K23.11 ENSG00000249967 10 97584374-97673910 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA076857 Tissue enhanced 0 parathyroid gland: 1.3 cerebral cortex: 0.9 -TMEM158 p40BBp, RIS1 ENSG00000249992 Transmembrane protein 158 (gene/pseudogene) 3 45224466-45226278 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 endometrium: 32.5;seminal vesicle: 31.8 smooth muscle: 25.4 -C15orf38-AP3S2 ENSG00000250021 C15orf38-AP3S2 readthrough 15 89834308-89912882 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA040513, HPA047173, HPA049270, HPA052278 Uncertain Approved Vesicles Expressed in all cerebral cortex: 19.5 -YJEFN3 FLJ44968, hYjeF_N3-19p13.11 ENSG00000250067 YjeF N-terminal domain containing 3 19 19528861-19537581 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060789 Approved Approved Mitochondria Tissue enhanced 0 cerebral cortex: 15.7;testis: 5.6 epididymis: 3.0 -DNAH10OS FLJ45278 ENSG00000250091 Dynein, axonemal, heavy chain 10 opposite strand 12 123926424-123934984 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA039786 Uncertain Tissue enhanced 0 cerebral cortex: 4.0 kidney: 1.5 -PCDHA10 CNR8, CNRN8, CNRS8, CRNR8, PCDH-ALPHA10 ENSG00000250120 Protocadherin alpha 10 5 140855883-141012344 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 17.5 thyroid gland: 4.2 -ARPC4-TTLL3 ENSG00000250151 ARPC4-TTLL3 readthrough 3 9793082-9835401 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed bone marrow: 4.3 -PTTG2 ENSG00000250254 Pituitary tumor-transforming 2 4 37960435-37961125 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA008890, HPA045034 Uncertain Approved Nucleoli
Cytosol Not detected bone marrow: 0.7 -XXbac-BPG246D15.9 ENSG00000250264 6 32813767-32838822 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA001312 Approved Approved Nuclear speckles
Endoplasmic reticulum Tissue enhanced 0 appendix: 16.0;spleen: 9.7 lymph node: 6.6 -KIAA1456 C8orf79, FLJ36980 ENSG00000250305 KIAA1456 8 12945642-13031503 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA024673 Approved Approved Nucleus
Cytosol Tissue enhanced 0 thyroid gland: 31.4 cerebral cortex: 6.6 -ZNF718 FLJ90036 ENSG00000250312 Zinc finger protein 718 4 124480-163989 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed thyroid gland: 8.7 -SMIM20 C4orf52 ENSG00000250317 Small integral membrane protein 20 4 25861830-25929874 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016552 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all epididymis: 86.3 -RP5-972B16.2 ENSG00000250349 X 37349330-38687674 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA003140 Uncertain Not detected skeletal muscle: 0.9 -GYPB CD235b, GPB, MNS, SS ENSG00000250361 Glycophorin B (MNS blood group) 4 143996104-144019345 Blood group antigen proteins, CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 5 bone marrow: 37.3 placenta: 7.2 -KIAA1210 ENSG00000250423 KIAA1210 X 119078635-119150579 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA000551, HPA048322 Supported Tissue enhanced 0 epididymis: 47.2;seminal vesicle: 27.1;testis: 58.1 prostate: 9.0 -RP5-877J2.1 ENSG00000250424 7 30852273-30923812 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA019206, HPA030130 Approved Approved Plasma membrane Tissue enhanced 0 gallbladder: 1.3 fallopian tube: 1.0 -CHCHD10 C22orf16, N27C7-4 ENSG00000250479 Coiled-coil-helix-coiled-coil-helix domain containing 10 22 23765834-23768443 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003440 Supported Supported Mitochondria Expressed in all skeletal muscle: 220.7 -FAM218A C4orf39, FLJ31659 ENSG00000250486 Family with sequence similarity 218, member A 4 164956948-164959122 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed testis: 5.6 -CDK3 ENSG00000250506 Cyclin-dependent kinase 3 17 76000906-76005999 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA007420 Uncertain Approved Cytosol Mixed skin: 29.2 -GPR162 A-2, GRCA ENSG00000250510 G protein-coupled receptor 162 12 6821545-6829972 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA055135 Supported Approved Microtubule organizing center Group enriched 6 cerebral cortex: 84.5;fallopian tube: 29.1 lung: 9.6 -ATP6V1E2 ATP6E1, ATP6EL2, ATP6V1EL2, MGC9341, VMA4 ENSG00000250565 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 2 46490750-46542557 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052784 Uncertain Group enriched 6 epididymis: 7.6;testis: 31.4 cerebral cortex: 3.2 -GLI4 HKR4, ZNF928 ENSG00000250571 GLI family zinc finger 4 8 143267433-143276931 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA023131 Uncertain Approved Nucleus
Cytokinetic bridge Expressed in all spleen: 9.0 -IQCJ-SCHIP1 ENSG00000250588 IQCJ-SCHIP1 readthrough 3 158962235-159897366 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA003243, HPA003445 Approved Approved Cytosol Tissue enhanced 0 cerebral cortex: 99.2 smooth muscle: 36.3 -XXbac-BPG32J3.19 ENSG00000250641 6 31706904-31717918 Predicted membrane proteins No evidence No evidence HPA008053 Uncertain Not detected testis: 0.5 -RP11-295K3.1 ENSG00000250644 11 1747806-1759051 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed gallbladder: 1.7 -CCDC169-SOHLH2 C13orf38-SOHLH2 ENSG00000250709 CCDC169-SOHLH2 readthrough 13 36168794-36297842 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA029182, HPA029183 Approved Vesicles Tissue enriched 29 testis: 19.4 seminal vesicle: 0.6 -RP11-322N21.2 ENSG00000250719 1 46175486-46176478 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 932 testis: 93.1 adipose tissue: 0.0 -SEPP1 SelP, SeP, SEPP ENSG00000250722 Selenoprotein P, plasma, 1 5 42799880-42887392 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036287 Approved Approved Nucleus
Golgi apparatus Expressed in all liver: 2937.1 -NT5C1B-RDH14 ENSG00000250741 NT5C1B-RDH14 readthrough 2 18555545-18589564 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA056683 Uncertain Tissue enriched 169 testis: 23.0 duodenum: 0.1 -USP17L20 ENSG00000250745 Ubiquitin specific peptidase 17-like family member 20 4 9258124-9260075 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected epididymis: 0.4 -PRODH2 HSPOX1 ENSG00000250799 Proline dehydrogenase (oxidase) 2 19 35799988-35813299 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051287 Approved Supported Nucleoplasm
Cytosol Group enriched 94 kidney: 132.6;liver: 45.0 testis: 0.9 -USP17L18 ENSG00000250844 Ubiquitin specific peptidase 17-like family member 18 4 9248630-9250581 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA045642 Uncertain Not detected adipose tissue: 0.0 -USP17L23 ENSG00000250913 Ubiquitin specific peptidase 17-like family member 23 4 9272364-9272914 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -RP11-484M3.5 ENSG00000251012 3 119147375-119187807 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.2 -RP11-101E3.5 ENSG00000251184 9 128941478-128957021 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected urinary bladder: 0.6 -ZNF674 MRX92, ZNF673B ENSG00000251192 Zinc finger protein 674 X 46497727-46545457 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA031026, HPA065295 Uncertain Validated Nucleoplasm Mixed prostate: 3.2 -TMED7-TICAM2 ENSG00000251201 TMED7-TICAM2 readthrough 5 115578642-115626161 Predicted secreted proteins Evidence at protein level Evidence at protein level HPA008960 Uncertain Mixed placenta: 4.6 -RP11-540D14.8 ENSG00000251246 1 155063748-155086807 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 1.2 testis: 0.7 -ZNF345 HZF10 ENSG00000251247 Zinc finger protein 345 19 36850361-36913029 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA025816 Uncertain Mixed testis: 18.4 -RFPL4B RNF211 ENSG00000251258 Ret finger protein-like 4B 6 112347330-112351296 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059324, HPA066464 Uncertain Tissue enriched 5 testis: 2.9 placenta: 0.5 -ALG1L2 ENSG00000251287 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 3 130081831-130113227 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA060392 Uncertain Uncertain Nucleoli fibrillar center
Endoplasmic reticulum Tissue enhanced 0 epididymis: 1.1;spleen: 1.1 breast: 0.3 -SHANK3 KIAA1650, prosap2, PSAP2, SPANK-2 ENSG00000251322 SH3 and multiple ankyrin repeat domains 3 22 50674415-50733298 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA003446 Approved Tissue enhanced 0 spleen: 47.1 adipose tissue: 24.5 -MSANTD3-TMEFF1 C9orf30-TMEFF1 ENSG00000251349 MSANTD3-TMEFF1 readthrough 9 100442271-100577636 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 48.1 testis: 10.1 -AP000350.10 ENSG00000251357 22 23862188-23895223 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA042960 Uncertain Not detected adrenal gland: 0.5 -ZNF550 MGC41917 ENSG00000251369 Zinc finger protein 550 19 57535257-57559863 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA003251 Uncertain Approved Vesicles
Microtubules Mixed parathyroid gland: 13.5 -DCANP1 C5orf20, DCNP1 ENSG00000251380 Dendritic cell-associated nuclear protein 5 135444214-135447348 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048308 Uncertain Not detected lymph node: 0.8 -FOXD1 FKHL8, FREAC4 ENSG00000251493 Forkhead box D1 5 73444827-73448362 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 4.8 adrenal gland: 2.9 -APITD1-CORT ENSG00000251503 APITD1-CORT readthrough 1 10430102-10452153 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 8 testis: 38.5 bone marrow: 5.0 -RP11-385D13.1 ENSG00000251537 17 15571491-15651653 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA023623, HPA066431 Uncertain Approved Plasma membrane
Cytosol Not detected skin: 0.5 -RP11-724O16.1 ENSG00000251569 2 169479480-169525922 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA046125 Uncertain Tissue enhanced 0 testis: 16.6 fallopian tube: 3.8 -PRB1 PM, PMF, PMS, PRB1L, PRB1M ENSG00000251655 Proline-rich protein BstNI subfamily 1 12 11351823-11395566 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enriched 4411 salivary gland: 6740.0 skin: 1.5 -PCDHA12 PCDH-ALPHA12 ENSG00000251664 Protocadherin alpha 12 5 140875302-141012344 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035812 Approved Approved Cytosol Tissue enhanced 0 lung: 2.7 cerebral cortex: 1.8 -PTX4 C16orf38 ENSG00000251692 Pentraxin 4, long 16 1485886-1488981 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA064718 Uncertain Cytosol Not detected testis: 0.9 -OC90 PLA2L ENSG00000253117 Otoconin 90 8 132024220-132059380 Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -RGS21 ENSG00000253148 Regulator of G-protein signaling 21 1 192316992-192367285 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA052843 Uncertain Not detected adipose tissue: 0.0 -PCDHGA12 CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12 ENSG00000253159 Protocadherin gamma subfamily A, 12 5 141430589-141512979 Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755 Uncertain Mixed cerebral cortex: 8.1 -C8orf88 ENSG00000253250 Chromosome 8 open reading frame 88 8 90958637-90985257 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enhanced 0 testis: 181.1 smooth muscle: 44.4 -CTC-534A2.2 ENSG00000253251 5 65624765-65630891 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA066071, HPA068764 Approved Supported Nucleoplasm
Nucleoli Mixed bone marrow: 10.0 -CCDC71L C7orf74, FLJ36031 ENSG00000253276 Coiled-coil domain containing 71-like 7 106656765-106660996 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA067925 Approved Approved Golgi apparatus
Actin filaments
Cytosol Mixed adipose tissue: 30.8 -HOXA10 HOX1, HOX1H ENSG00000253293 Homeobox A10 7 27170591-27180261 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB019384 Approved Supported Nucleoplasm
Nuclear bodies Tissue enhanced 0 endometrium: 116.3;smooth muscle: 67.0 prostate: 42.4 -TMEM200B TTMB ENSG00000253304 Transmembrane protein 200B 1 29119428-29123935 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA055254 Uncertain Tissue enhanced 0 endometrium: 68.0 seminal vesicle: 52.6 -PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 Protocadherin gamma subfamily B, 6 5 141408021-141512979 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008755 Uncertain Tissue enhanced 0 cerebral cortex: 20.9 parathyroid gland: 11.7 -SERPINE3 ENSG00000253309 Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 13 51335773-51364735 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA051904, HPA055804 Uncertain Mixed skin: 1.0 -C1orf210 MGC52423 ENSG00000253313 Chromosome 1 open reading frame 210 1 43281883-43285617 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA013788 Uncertain Uncertain Nucleoli Mixed duodenum: 45.5 -TRNP1 C1orf225, LOC388610 ENSG00000253368 TMF1-regulated nuclear protein 1 1 26993707-27000898 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 stomach: 118.0 esophagus: 49.8 -SMIM18 ENSG00000253457 Small integral membrane protein 18 8 30638600-30646064 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence Evidence at protein level HPA066648 Supported Uncertain Nucleus
Centrosome Tissue enriched 9 cerebral cortex: 11.1 adrenal gland: 1.3 -PCDHGA5 CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5 ENSG00000253485 Protocadherin gamma subfamily A, 5 5 141364232-141512979 Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755 Uncertain Mixed cerebral cortex: 3.8 -NACA2 MGC71999, NACAL ENSG00000253506 Nascent polypeptide-associated complex alpha subunit 2 17 61590426-61591202 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA073152, HPA073648 Approved Cytosol Tissue enriched 124 testis: 103.5 ovary: 0.8 -PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 Protocadherin gamma subfamily A, 7 5 141382739-141512979 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755, HPA077995 Uncertain Uncertain Plasma membrane
Cell Junctions Tissue enhanced 0 cerebral cortex: 7.4 thyroid gland: 3.2 -PYDC2 POP2 ENSG00000253548 Pyrin domain containing 2 3 191461163-191461456 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA055895 Uncertain Not detected adipose tissue: 0.0 -SLC10A5 ENSG00000253598 Solute carrier family 10, member 5 8 81693607-81696174 Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA025966 Uncertain Approved Plasma membrane Mixed liver: 3.0 -EIF5AL1 bA342M3.3, EIF5AP1 ENSG00000253626 Eukaryotic translation initiation factor 5A-like 1 10 79512601-79516440 Predicted intracellular proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 10 testis: 20.0 parathyroid gland: 2.0 -ALG11 KIAA0266 ENSG00000253710 ALG11, alpha-1,2-mannosyltransferase 13 52012398-52029664 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047214 Approved Expressed in all thyroid gland: 23.4 -ATXN7L3B lnc-SCA7 ENSG00000253719 Ataxin 7-like 3B 12 74537827-74545430 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA056612 Approved Nucleoplasm Expressed in all cerebral cortex: 61.7 -PRKDC DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7 ENSG00000253729 Protein kinase, DNA-activated, catalytic polypeptide 8 47773108-47960183 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005167, HPA035174 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 30.0 -PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 Protocadherin gamma subfamily A, 6 5 141373914-141512979 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755 Uncertain Mixed ovary: 3.8 -PCDHGA8 KIAA0327, PCDH-GAMMA-A8 ENSG00000253767 Protocadherin gamma subfamily A, 8 5 141390157-141512979 Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA008755 Uncertain Not detected thyroid gland: 0.7 -UTP14C 2700066J21Rik, KIAA0266 ENSG00000253797 UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) 13 52024691-52033600 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047217, HPA054023 Uncertain Approved Nucleoli
Cytosol Expressed in all thyroid gland: 25.5 -ETV3L FLJ16478 ENSG00000253831 Ets variant 3-like 1 157092044-157099808 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected breast: 0.9 -PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 Protocadherin gamma subfamily A, 10 5 141412987-141512979 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755 Uncertain Tissue enriched 5 cerebral cortex: 28.1 placenta: 5.1 -PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 Protocadherin gamma subfamily A, 11 5 141421047-141512979 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755 Uncertain Mixed cerebral cortex: 3.2 -PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 Protocadherin gamma subfamily B, 2 5 141360042-141512979 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755, HPA077526 Uncertain Uncertain Vesicles Mixed cerebral cortex: 6.5 -PCDHGB4 CDH20, FIB2, PCDH-GAMMA-B4 ENSG00000253953 Protocadherin gamma subfamily B, 4 5 141387698-141512979 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755 Uncertain Mixed placenta: 4.2 -CLDN23 CLDNL ENSG00000253958 Claudin 23 8 8701938-8704106 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA070578 Uncertain Nucleus
Plasma membrane Tissue enhanced 0 colon: 24.1;stomach: 24.9 small intestine: 16.9 -ZNF260 ozrf1, Zfp260 ENSG00000254004 Zinc finger protein 260 19 36510695-36528660 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA028806 Approved Supported Nucleoplasm
Cytosol Mixed parathyroid gland: 20.3 -LYN JTK8 ENSG00000254087 LYN proto-oncogene, Src family tyrosine kinase 8 55879813-56014168 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001231, CAB004492 Supported Supported Golgi apparatus
Vesicles
Plasma membrane Tissue enhanced 0 spleen: 163.6 appendix: 133.8 -PINX1 FLJ20565, LPTL, LPTS, MGC8850, PinX1 ENSG00000254093 PIN2/TERF1 interacting, telomerase inhibitor 1 8 10764963-10839884 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023139 Uncertain Expressed in all testis: 16.0 -PCDHGB7 ME6, PCDH-GAMMA-B7 ENSG00000254122 Protocadherin gamma subfamily B, 7 5 141417645-141512979 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008755 Uncertain Mixed ovary: 10.2 -NPIPB11 ENSG00000254206 Nuclear pore complex interacting protein family, member B11 16 29381354-29404029 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA053611 Approved Approved Nucleoplasm Mixed parathyroid gland: 14.2 -PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 Protocadherin gamma subfamily B, 1 5 141350102-141512979 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755, HPA076182 Uncertain Approved Plasma membrane
Focal adhesion sites
Midbody Tissue enriched 12 cerebral cortex: 23.8 endometrium: 2.0 -PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 Protocadherin gamma subfamily A, 3 5 141343829-141512979 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008755, HPA039295 Uncertain Approved Nucleoplasm
Centrosome Tissue enhanced 0 cerebral cortex: 6.5 ovary: 3.1 -LRRC24 LRRC14OS ENSG00000254402 Leucine rich repeat containing 24 8 144522377-144527032 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA028171, HPA052250 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 3.1;prostate: 3.0 parathyroid gland: 1.7 -SIGLEC14 ENSG00000254415 Sialic acid binding Ig-like lectin 14 19 51642553-51646801 Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014377 Uncertain Tissue enhanced 0 appendix: 36.1;spleen: 56.5 bone marrow: 18.7 -PBOV1 UC28, UROC28 ENSG00000254440 Prostate and breast cancer overexpressed 1 6 138215986-138218491 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA063021 Uncertain Not detected bone marrow: 0.1 -OR4D10 OR4D10P, OST711 ENSG00000254466 Olfactory receptor, family 4, subfamily D, member 10 11 59477373-59478396 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -RP11-849H4.2 ENSG00000254469 Putative short transient receptor potential channel 2-like protein 11 71865509-71928654 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA051121, HPA058841 Uncertain Supported Nucleoli Tissue enhanced 0 epididymis: 35.8 thyroid gland: 7.3 -AP5B1 AP-5, DKFZp761E198, PP1030 ENSG00000254470 Adaptor-related protein complex 5, beta 1 subunit 11 65775893-65780802 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA065739, HPA067880 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Expressed in all bone marrow: 25.1 -CHMP4A C14orf123, HSPC134, VPS32A ENSG00000254505 Charged multivesicular body protein 4A 14 24209583-24213869 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA068473 Approved Expressed in all parathyroid gland: 128.0 -SIGLEC12 S2V, Siglec-12, Siglec-L1, Siglec-XII, SIGLECL1, SLG ENSG00000254521 Sialic acid binding Ig-like lectin 12 (gene/pseudogene) 19 51491357-51501789 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 appendix: 6.6;spleen: 13.0 smooth muscle: 3.6 -PABPC4L ENSG00000254535 Poly(A) binding protein, cytoplasmic 4-like 4 134196333-134201748 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 parathyroid gland: 12.6;placenta: 14.5 endometrium: 6.4 -RP11-108K14.8 ENSG00000254536 10 133390834-133420495 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA037826, HPA037827 Uncertain Approved Mitochondria Tissue enhanced 0 testis: 2.5 duodenum: 1.3 -OMP ENSG00000254550 Olfactory marker protein 11 77102840-77103331 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 duodenum: 2.7;small intestine: 2.8 rectum: 2.0 -MAGEL2 NDNL1, nM15 ENSG00000254585 Melanoma antigen family L2 15 23643544-23647841 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 3.3 cervix: 2.9 -CSNK2A3 CSNK2A1P ENSG00000254598 Casein kinase 2, alpha 3 polypeptide 11 11351942-11353357 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059206 Approved Nucleoplasm Not detected testis: 0.5 -ARMS2 ARMD8, LOC387715 ENSG00000254636 Age-related maculopathy susceptibility 2 10 122454653-122457352 Disease related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA067225 Approved Tissue enhanced 0 placenta: 2.1;testis: 2.8 ovary: 1.2 -INS IDDM1, IDDM2 ENSG00000254647 Insulin 11 2159779-2161341 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000048, HPA004932, CAB012098, CAB053843 Supported Tissue enriched 27 pancreas: 1850.8 skin: 68.1 -RTL1 Mar1, MART1, PEG11 ENSG00000254656 Retrotransposon-like 1 14 100880655-100884847 Predicted membrane proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA066979 Approved Cytosol Group enriched 10 adrenal gland: 2.4;placenta: 4.8 cerebral cortex: 0.3 -FPGT GFPP ENSG00000254685 Fucose-1-phosphate guanylyltransferase 1 74198212-74234086 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA072331 Uncertain Vesicles Expressed in all thyroid gland: 32.7 -RP11-468E2.1 ENSG00000254692 14 24189157-24213473 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA059249 Approved Approved Golgi apparatus Expressed in all parathyroid gland: 53.3 -RP11-565P22.6 ENSG00000254706 1 162365407-162383531 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 seminal vesicle: 4.2 gallbladder: 2.3 -IGLL5 ENSG00000254709 Immunoglobulin lambda-like polypeptide 5 22 22887780-22896107 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 tonsil: 868.7 urinary bladder: 660.2 -MEX3A RKHD4 ENSG00000254726 Mex-3 RNA binding family member A 1 156072013-156081998 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062703 Supported Cytosol Tissue enhanced 0 endometrium: 5.9;ovary: 5.9 cerebral cortex: 4.1 -OR10G4 ENSG00000254737 Olfactory receptor, family 10, subfamily G, member 4 11 124015575-124016510 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected pancreas: 0.1 -EEF1G EF1G ENSG00000254772 Eukaryotic translation elongation factor 1 gamma 11 62559601-62574086 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040688 Approved Approved Mitochondria Expressed in all ovary: 2987.8 -CKLF-CMTM1 ENSG00000254788 CKLF-CMTM1 readthrough 16 66552587-66579135 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA017136 Approved Mixed testis: 4.1 -SLC22A18AS BWR1B, BWSCR1B, ORCTL2S, p27-BWR1B, SLC22A1LS ENSG00000254827 Solute carrier family 22 (organic cation transporter), member 18 antisense 11 2887780-2903740 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA068288 Supported Supported Nucleoplasm Tissue enhanced 0 colon: 14.7;duodenum: 13.9 rectum: 11.2 -OR5M10 ENSG00000254834 Olfactory receptor, family 5, subfamily M, member 10 11 56576774-56577721 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -NPIPA2 ENSG00000254852 Nuclear pore complex interacting protein family, member A2 16 14748066-14765413 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA053611 Approved Uncertain Nucleoplasm Mixed testis: 2.8 -MPV17L2 FKSG24, MGC12972 ENSG00000254858 MPV17 mitochondrial membrane protein-like 2 19 18193182-18196948 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043111 Uncertain Approved Plasma membrane
Cytosol Expressed in all seminal vesicle: 16.2 -AC113404.1 ENSG00000254893 Ras-related protein Rap-1b-like protein 5 76170093-76174331 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 8 small intestine: 3.4 adrenal gland: 0.4 -BORCS8 MEF2BNB ENSG00000254901 BLOC-1 related complex subunit 8 19 19176903-19192591 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA045700 Approved Approved Nucleoplasm
Vesicles Mixed cerebral cortex: 17.4 -RP11-872D17.8 ENSG00000254979 11 57387365-57424059 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA038515 Supported Tissue enhanced 0 bone marrow: 7.8;placenta: 10.5 skin: 5.8 -DPP3 ENSG00000254986 Dipeptidyl-peptidase 3 11 66480013-66509657 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035780, HPA035781 Approved Validated Nuclear speckles
Plasma membrane
Cytosol Expressed in all colon: 30.0 -ANKHD1-EIF4EBP3 MASK-BP3 ENSG00000254996 ANKHD1-EIF4EBP3 readthrough 5 140401908-140549569 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA008718 Approved Expressed in all parathyroid gland: 39.6 -KRTAP5-9 KRN1, KRTAP5-1, KRTAP5.9 ENSG00000254997 Keratin associated protein 5-9 11 71548418-71549553 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 2.6 epididymis: 1.8 -BRK1 C3orf10, HSPC300, MDS027 ENSG00000254999 BRICK1, SCAR/WAVE actin-nucleating complex subunit 3 10115592-10127190 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA060391 Approved Nuclear speckles
Cell Junctions Expressed in all fallopian tube: 223.3 -UBTFL1 C11orf27 ENSG00000255009 Upstream binding transcription factor, RNA polymerase I-like 1 11 90085950-90087131 Predicted intracellular proteins, Transcription factors No evidence No evidence No evidence Not detected adipose tissue: 0.0 -OR5M1 OST050 ENSG00000255012 Olfactory receptor, family 5, subfamily M, member 1 11 56612555-56613502 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -SAA2-SAA4 ENSG00000255071 SAA2-SAA4 readthrough 11 18231423-18248635 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA060139 Uncertain Tissue enhanced 0 adipose tissue: 27.8;cervix, uterine: 22.5;liver: 15.0 breast: 5.4 -PIGY MGC14156 ENSG00000255072 Phosphatidylinositol glycan anchor biosynthesis, class Y 4 88521573-88521789 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA059018 Uncertain Tissue enriched 10 colon: 1.0 adipose tissue: 0.0 -TBC1D26 MGC51025 ENSG00000255104 TBC1 domain family, member 26 17 15699692-15744783 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA050460 Uncertain Tissue enriched 72 testis: 12.6 tonsil: 0.1 -CHMP1B C18orf2, CHMP1.5, Vps46B ENSG00000255112 Charged multivesicular body protein 1B 18 11851396-11854449 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA061997, HPA062896 Supported Supported Nucleus
Midbody Expressed in all thyroid gland: 86.7 -EID3 FLJ25832, NSE4B, NSMCE4B ENSG00000255150 EP300 interacting inhibitor of differentiation 3 12 104303739-104305202 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA059367 Uncertain Supported Nucleus
Nucleoli Tissue enriched 14 testis: 111.7 seminal vesicle: 7.7 -GLYATL1P3 ENSG00000255151 Glycine-N-acyltransferase-like 1 pseudogene 3 11 59086307-59094786 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA039501 Uncertain Uncertain Golgi apparatus
Cytosol Tissue enhanced 0 breast: 10.9;lymph node: 3.5 tonsil: 2.1 -RP11-80H18.3 ENSG00000255154 Hydroxyacyl-thioester dehydratase type 2, mitochondrial 3 58306262-58318574 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA066812 Supported Nucleoli
Mitochondria Expressed in all thyroid gland: 14.6 -CCDC166 ENSG00000255181 Coiled-coil domain containing 166 8 143706694-143708109 Predicted intracellular proteins No evidence No evidence No evidence HPA025058 Uncertain Not detected testis: 0.6 -NANOGP8 ENSG00000255192 Nanog homeobox pseudogene 8 15 35084193-35085110 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected testis: 0.7 -CARD17 INCA ENSG00000255221 Caspase recruitment domain family, member 17 11 105092469-105101431 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 8.0 lymph node: 4.6 -OR5M11 OR11-199 ENSG00000255223 Olfactory receptor, family 5, subfamily M, member 11 11 56542340-56543257 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.1 -FXYD6-FXYD2 ENSG00000255245 FXYD6-FXYD2 readthrough 11 117820163-117876667 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA068838 Approved Tissue enhanced 0 kidney: 5.5 salivary gland: 2.2 -PRR23D1 ENSG00000255251 Proline rich 23 domain containing 1 8 7539628-7542450 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 48 epididymis: 74.3 testis: 1.5 -OR8G5 OR8G5P, OR8G6 ENSG00000255298 Olfactory receptor, family 8, subfamily G, member 5 11 124264827-124265867 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 30 testis: 6.1 placenta: 0.2 -EID1 C15orf3, CRI1, EID-1 ENSG00000255302 EP300 interacting inhibitor of differentiation 1 15 48877886-48880183 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA051122, HPA051123 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 314.2 -OR52B2 ENSG00000255307 Olfactory receptor, family 52, subfamily B, member 2 11 6169330-6170408 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -NOX5 NOX5A, NOX5B ENSG00000255346 NADPH oxidase, EF-hand calcium binding domain 5 15 68930525-69062743 Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 spleen: 13.4 testis: 3.6 -CCDC179 ENSG00000255359 Coiled-coil domain containing 179 11 22846931-22860426 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 354 testis: 45.9 epididymis: 0.1 -TAS2R43 T2R52 ENSG00000255374 Taste receptor, type 2, member 43 12 11091287-11134244 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -PRR23D2 ENSG00000255378 Proline rich 23 domain containing 2 8 7778591-7781413 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 48 epididymis: 74.3 testis: 1.5 -HCAR3 GPR109B, HCA3, HM74 ENSG00000255398 Hydroxycarboxylic acid receptor 3 12 122714756-122716892 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA028660 Approved Approved Cell Junctions Tissue enhanced 0 bone marrow: 16.7;spleen: 22.1 appendix: 12.6 -PCDHA3 PCDH-ALPHA3 ENSG00000255408 Protocadherin alpha 3 5 140801028-141012344 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035667 Uncertain Mixed endometrium: 2.5 -EBLN2 ENSG00000255423 Endogenous Bornavirus-like nucleoprotein 2 3 73061659-73063337 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA062510, HPA068795 Uncertain Approved Nucleoplasm
Nuclear bodies Mixed bone marrow: 10.2 -RP11-831H9.11 ENSG00000255432 11 62649694-62665178 Predicted intracellular proteins No evidence No evidence Not detected cerebral cortex: 0.5 -RP11-196G11.1 ENSG00000255439 16 31083439-31094956 Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA042720 Uncertain Not detected skin: 0.5 -CARD18 ICEBERG, pseudo-ICE, UNQ5804 ENSG00000255501 Caspase recruitment domain family, member 18 11 105137721-105139726 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038582 Approved Group enriched 7 breast: 10.5;skin: 29.7 esophagus: 3.0 -NPIPB8 ENSG00000255524 Nuclear pore complex interacting protein family, member B8 16 28637654-28658682 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA011188, HPA053611 Uncertain Approved Nucleoplasm Tissue enriched 11 testis: 12.8 small intestine: 1.1 -NEDD8-MDP1 ENSG00000255526 NEDD8-MDP1 readthrough 14 24213955-24232352 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA003064 Uncertain Approved Nucleoplasm Tissue enhanced 0 parathyroid gland: 2.6 testis: 1.8 -POLR2M GCOM1, Gdown, Gdown1, GRINL1A ENSG00000255529 Polymerase (RNA) II (DNA directed) polypeptide M 15 57706629-57782762 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068141 Approved Nucleoplasm Expressed in all endometrium: 56.3 -LY6G6E C6orf22, G6e ENSG00000255552 Lymphocyte antigen 6 complex, locus G6E (pseudogene) 6 31711771-31714065 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 1.2 thyroid gland: 0.8 -FDXACB1 hCG_2033039, LOC91893 ENSG00000255561 Ferredoxin-fold anticodon binding domain containing 1 11 111874056-111881243 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA039012, HPA061375 Approved Uncertain Nucleus
Cytosol Mixed testis: 6.6 -OR10G2 ENSG00000255582 Olfactory receptor, family 10, subfamily G, member 2 14 21633836-21634940 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected lymph node: 0.2 -RAB44 dJ431A14.3, RASD3, RASL13 ENSG00000255587 RAB44, member RAS oncogene family 6 36697851-36733183 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 28 bone marrow: 38.8 gallbladder: 1.3 -RP11-277P12.6 ENSG00000255641 12 10412312-10436001 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA062570 Uncertain Group enriched 7 cerebral cortex: 8.2;spleen: 6.2 bone marrow: 1.0 -TRIL KIAA0644 ENSG00000255690 TLR4 interactor with leucine-rich repeats 7 28953358-28958292 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 25.0 kidney: 5.7 -OR4D2 ENSG00000255713 Olfactory receptor, family 4, subfamily D, member 2 17 58169656-58170579 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -CTC-435M10.3 ENSG00000255730 19 41350853-41425001 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA036640 Approved Mixed cerebral cortex: 9.2 -RP13-512J5.1 ENSG00000255767 2 3531984-3547957 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed smooth muscle: 23.8 -OR6J1 OR6J1P, OR6J2 ENSG00000255804 Olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene) 14 22633768-22634811 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -MTRNR2L8 ENSG00000255823 MT-RNR2-like 8 11 10507887-10509189 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all heart muscle: 1840.4 -TIFAB ENSG00000255833 TRAF-interacting protein with forkhead-associated domain, family member B 5 135444218-135452399 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA049372 Uncertain Tissue enhanced 0 appendix: 5.0;lymph node: 6.4;tonsil: 4.7 spleen: 3.6 -RP4-559A3.7 ENSG00000255835 1 225886696-225924278 Predicted intracellular proteins No evidence No evidence Not detected cerebral cortex: 0.1 -TAS2R20 T2R20, T2R56, TAS2R49 ENSG00000255837 Taste receptor, type 2, member 20 12 10996495-10997875 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected skin: 0.8 -AC073610.5 ENSG00000255863 12 48921963-48939663 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -CYP2A6 CPA6, CYP2A, CYP2A3 ENSG00000255974 Cytochrome P450, family 2, subfamily A, polypeptide 6 19 40843538-40882210 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046713, HPA047262 Supported Tissue enriched 70 liver: 854.2 breast: 12.2 -CTSO CTSO1 ENSG00000256043 Cathepsin O 4 155924118-155953917 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA002041 Approved Expressed in all gallbladder: 32.5 -MTRNR2L10 ENSG00000256045 MT-RNR2-like 10 X 55181391-55182920 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed kidney: 68.3 -APOPT1 APOP-1, C14orf153, MGC2562 ENSG00000256053 Apoptogenic 1, mitochondrial 14 103562962-103607523 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all testis: 89.3 -TRAPPC2P1 ENSG00000256060 Trafficking protein particle complex subunit 2B 19 57363511-57365353 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA063308 Approved Nucleoplasm
Endoplasmic reticulum
Vesicles Expressed in all testis: 28.7 -DYX1C1 CILD25, DNAAF4, EKN1, FLJ37882 ENSG00000256061 Dyslexia susceptibility 1 candidate 1 15 55410525-55508234 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA051048 Uncertain Approved Plasma membrane
Cytosol Tissue enhanced 0 testis: 20.4 fallopian tube: 17.5 -ZNF432 KIAA0798 ENSG00000256087 Zinc finger protein 432 19 52031379-52095738 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052082, HPA060274, HPA065606 Uncertain Supported Nucleoplasm Expressed in all prostate: 20.7 -AP000721.4 ENSG00000256100 11 63974620-63988346 Predicted secreted proteins No evidence No evidence HPA055942 Uncertain Not detected epididymis: 0.0 -SMLR1 ENSG00000256162 Small leucine-rich protein 1 6 130827406-130837135 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA066060 Uncertain Group enriched 5 duodenum: 12.5;liver: 28.9;small intestine: 11.6 kidney: 3.2 -TAS2R30 T2R30, TAS2R47 ENSG00000256188 Taste receptor, type 2, member 30 12 11132958-11134644 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.2 -MTRNR2L3 ENSG00000256222 MT-RNR2-like 3 20 57358442-57359980 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.3 -ZNF10 KOX1 ENSG00000256223 Zinc finger protein 10 12 133130575-133159465 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA003204 Uncertain Approved Nucleus
Vesicles
Plasma membrane Expressed in all parathyroid gland: 40.2 -ZNF486 KRBO2, MGC2396 ENSG00000256229 Zinc finger protein 486 19 20167228-20200490 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 thyroid gland: 63.3 urinary bladder: 17.8 -SMIM3 C5orf62, MSTP150, NID67 ENSG00000256235 Small integral membrane protein 3 5 150777946-150796734 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA075345 Approved Vesicles Expressed in all adipose tissue: 108.7 -HMBS PBGD, PORC, UPS ENSG00000256269 Hydroxymethylbilane synthase 11 119084866-119093549 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006114, HPA050659 Supported Approved Lipid droplets Tissue enriched 6 bone marrow: 53.0 parathyroid gland: 9.6 -ZNF225 ENSG00000256294 Zinc finger protein 225 19 44112181-44134816 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA073778 Approved Nucleoplasm Tissue enhanced 0 testis: 22.7 breast: 10.5 -CTD-3074O7.11 ENSG00000256349 11 66509079-66533613 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA058283 Uncertain Uncertain Midbody Not detected lymph node: 0.3 -PPIAL4D ENSG00000256374 Peptidylprolyl isomerase A (cyclophilin A)-like 4D 1 145241630-145242124 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA058345 Uncertain Not detected skin: 0.1 -ASIC5 ACCN5, HINAC, INAC ENSG00000256394 Acid sensing (proton gated) ion channel family member 5 4 155829729-155866273 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA014903, HPA029444 Approved Group enriched 19 duodenum: 2.4;small intestine: 1.3 epididymis: 0.0 -TAS2R31 T2R31, T2R53, TAS2R44 ENSG00000256436 Taste receptor, type 2, member 31 12 11030387-11031407 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected parathyroid gland: 0.3 -DND1 MGC34750, RBMS4 ENSG00000256453 DND microRNA-mediated repression inhibitor 1 5 140670794-140673586 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 22 testis: 8.9 spleen: 0.4 -SALL3 ZNF796 ENSG00000256463 Spalt-like transcription factor 3 18 78980275-79002677 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA016656 Uncertain Tissue enhanced 0 cerebral cortex: 4.1;prostate: 2.5 kidney: 0.9 -RP11-73M18.2 ENSG00000256500 14 103562962-103685924 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA044617, HPA052450 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced 0 cerebral cortex: 21.6;testis: 21.5 skeletal muscle: 9.1 -AP003419.11 ENSG00000256514 11 67351572-67373584 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA071529 Uncertain Nucleus
Nucleoli
Mitochondria
Cytosol Expressed in all tonsil: 105.1 -POLG2 HP55, MTPOLB ENSG00000256525 Polymerase (DNA directed), gamma 2, accessory subunit 17 64477785-64497036 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB017030, HPA023202 Approved Approved Nuclear bodies
Mitochondria Mixed testis: 20.1 -SMIM10L1 ENSG00000256537 Small integral membrane protein 10 like 1 12 11171222-11176016 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed cerebral cortex: 15.7 -OR13A1 ENSG00000256574 Olfactory receptor, family 13, subfamily A, member 1 10 45302654-45315608 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057237 Uncertain Not detected urinary bladder: 0.5 -RP11-286N22.8 ENSG00000256591 11 61429220-61485822 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA039732 Uncertain Mixed cervix: 8.3 -MTRNR2L1 ENSG00000256618 MT-RNR2-like 1 17 22523111-22524663 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all heart muscle: 1053.3 -RP13-672B3.2 ENSG00000256632 12 132688049-132714912 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 duodenum: 2.7 testis: 0.6 -CLEC12B ENSG00000256660 C-type lectin domain family 12, member B 12 10010627-10018619 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA026973 Uncertain Tissue enhanced 0 testis: 27.2 skin: 5.5 -LIMS3L ENSG00000256671 LIM and senescent cell antigen-like domains 3-like 2 110446640-110473075 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level HPA058455 Uncertain Not detected adipose tissue: 0.0 -ZNF350 ZBRK1, ZFQR ENSG00000256683 Zinc finger protein 350 19 51964343-51986856 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA001521 Uncertain Supported Nucleoplasm
Nuclear bodies Mixed prostate: 47.4 -PGA5 ENSG00000256713 Pepsinogen 5, group I (pepsinogen A) 11 61241042-61251448 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046875 Supported Tissue enriched 590 stomach: 2980.0 fallopian tube: 5.0 -STH MAPTIT ENSG00000256762 Saitohin 17 45999250-45999694 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 1.4 breast: 0.5 -ZNF253 BMZF-1, FLJ90391, ZNF411 ENSG00000256771 Zinc finger protein 253 19 19865886-19894674 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed thyroid gland: 25.8 -KLRF2 NKp65 ENSG00000256797 Killer cell lectin-like receptor subfamily F, member 2 12 9881489-9895833 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 skin: 14.1 breast: 1.3 -CAPNS2 MGC12536, MGC14804 ENSG00000256812 Calpain, small subunit 2 16 55566672-55567687 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 esophagus: 60.1;skin: 109.5 urinary bladder: 31.5 -CTD-2140B24.4 ENSG00000256825 12 133130984-133202369 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.4 -SLC5A8 AIT ENSG00000256870 Solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 12 101155493-101210407 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cervix, uterine: 16.2;thyroid gland: 14.8 kidney: 3.5 -MTRNR2L7 ENSG00000256892 MT-RNR2-like 7 10 37601440-37602974 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected skeletal muscle: 0.1 -LIMS3 ENSG00000256977 LIM and senescent cell antigen-like domains 3 2 109898428-109924868 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058455 Uncertain Approved Focal adhesion sites
Cytosol Tissue enhanced 0 fallopian tube: 9.8 endometrium: 8.8 -KHDC1L RP11-257K9.7 ENSG00000256980 KH homology domain containing 1-like 6 73223544-73225770 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 testis: 4.6 lung: 1.0 -GPR142 PGR2 ENSG00000257008 G protein-coupled receptor 142 17 74367407-74372622 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA031392 Uncertain Uncertain Plasma membrane
Cell Junctions
Cytosol Not detected appendix: 0.1 -HP ENSG00000257017 Haptoglobin 16 72054592-72061055 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003787, HPA047750 Supported Approved Vesicles Tissue enriched 181 liver: 28321.0 bone marrow: 156.1 -RP11-545J16.1 ENSG00000257046 12 20815674-21090245 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA050892 Uncertain Tissue enriched 13 breast: 26.4 liver: 2.0 -KIAA1147 LCHN ENSG00000257093 KIAA1147 7 141656728-141702153 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA029467, HPA061437 Approved Approved Golgi apparatus Expressed in all cerebral cortex: 21.2 -LSM14A C19orf13, DKFZP434D1335, FAM61A, RAP55, RAP55A ENSG00000257103 LSM14A mRNA processing body assembly factor 19 34172504-34229515 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017961 Approved Supported Cytosol
Cytoplasmic bodies Mixed thyroid gland: 37.3 -NHLRC4 ENSG00000257108 NHL repeat containing 4 16 566996-569495 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 18.7 parathyroid gland: 6.2 -OR11H12 ENSG00000257115 Olfactory receptor, family 11, subfamily H, member 12 14 18601045-18602129 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA047370 Uncertain Not detected adipose tissue: 0.0 -CLLU1 ENSG00000257127 Chronic lymphocytic leukemia up-regulated 1 12 92421531-92431002 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -TAS2R38 PTC, T2R61 ENSG00000257138 Taste receptor, type 2, member 38 7 141972631-141973773 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA043862, HPA054366 Uncertain Not detected rectum: 0.3 -HOXA10-HOXA9 ENSG00000257184 7 27163535-27180013 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 endometrium: 1.0 prostate: 0.3 -GATC 15E1.2, FLJ37000, gatC ENSG00000257218 Glutamyl-tRNA(Gln) amidotransferase, subunit C 12 120446438-120463749 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 18.9 -ZBED6 ENSG00000257315 Zinc finger, BED-type containing 6 1 203796309-203800558 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA068807 Approved Nucleoplasm
Microtubule organizing center Mixed parathyroid gland: 17.6 -MGAM MGA ENSG00000257335 Maltase-glucoamylase 7 141907813-142106747 Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002270 Supported Tissue enhanced 0 duodenum: 61.0;small intestine: 99.1 epididymis: 30.6 -FNTB FPTB ENSG00000257365 Farnesyltransferase, CAAX box, beta 14 64986720-65062652 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062743 Approved Approved Centrosome Expressed in all parathyroid gland: 17.7 -RP11-762I7.5 ENSG00000257390 12 55757275-55827546 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA017653, HPA030902, HPA030903 Uncertain Validated Nuclear speckles Tissue enriched 7 testis: 15.6 epididymis: 2.3 -RP11-603J24.9 ENSG00000257411 12 56101331-56109289 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed cervix: 22.2 -ZNF878 ENSG00000257446 Zinc finger protein 878 19 12043805-12052939 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA052735 Uncertain Approved Nucleus
Nucleoli Mixed testis: 1.4 -RPL36A-HNRNPH2 ENSG00000257529 RPL36A-HNRNPH2 readthrough X 101391011-101412297 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA077586 Approved Plasma membrane
Cytosol Mixed ovary: 2.6 -ZNF625 ENSG00000257591 Zinc finger protein 625 19 12142090-12156729 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA074014 Approved Nucleus
Mitochondria Mixed thyroid gland: 4.7 -GALNT4 GalNAc-T4 ENSG00000257594 Polypeptide N-acetylgalactosaminyltransferase 4 12 89519408-89524806 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA076116 Approved Golgi apparatus Mixed stomach: 30.8 -INAFM1 PRR24 ENSG00000257704 InaF-motif containing 1 19 47274453-47275707 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA064015 Uncertain Expressed in all adrenal gland: 23.4 -CNPY2 Cnpy2, HP10390, TMEM4, ZSIG9 ENSG00000257727 Canopy FGF signaling regulator 2 12 56309842-56316336 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038465, HPA038466 Supported Supported Cytosol Expressed in all epididymis: 85.9 -MGAM2 ENSG00000257743 Maltase-glucoamylase 2 (putative) 7 142111749-142222324 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA055697 Supported Approved Vesicles
Cytosol Group enriched 5 duodenum: 12.2;small intestine: 10.6 salivary gland: 2.1 -RP11-162P23.2 ENSG00000257767 12 111753890-111791418 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adipose tissue: 64.1 stomach: 16.7 -RP11-571M6.15 ENSG00000257921 12 57773028-57787046 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected lymph node: 0.1 -CUX1 CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6 ENSG00000257923 Cut-like homeobox 1 7 101815904-102283957 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003277, HPA003317 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all thyroid gland: 82.3 -TEN1 C17orf106, FLJ39785 ENSG00000257949 TEN1 CST complex subunit 17 75979220-76000586 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA065069 Supported Nucleus Expressed in all skin: 29.9 -OR9A4 ENSG00000258083 Olfactory receptor, family 9, subfamily A, member 4 7 141918817-141919909 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Not detected testis: 0.2 -MAP1LC3B2 ATG8G ENSG00000258102 Microtubule-associated protein 1 light chain 3 beta 2 12 116548105-116576448 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043000, HPA052474, HPA052484, HPA053767 Uncertain Approved Microtubule organizing center Mixed adrenal gland: 2.7 -RP11-347C12.3 ENSG00000258130 16 30204316-30209071 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA053608 Uncertain Tissue enhanced 0 testis: 9.9 fallopian tube: 4.1 -RP11-345J4.3 ENSG00000258150 16 29464967-29467833 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA053608 Uncertain Tissue enhanced 0 testis: 7.0 gallbladder: 4.1 -PRSS58 TRYX3 ENSG00000258223 Protease, serine, 58 7 142252143-142258058 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 123 testis: 20.8 smooth muscle: 0.1 -CLEC5A CLECSF5, MDL-1 ENSG00000258227 C-type lectin domain family 5, member A 7 141927357-141947007 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 appendix: 10.8;bone marrow: 27.4 lung: 4.9 -CHURC1 C14orf52, FLJ33064, My015 ENSG00000258289 Churchill domain containing 1 14 64914361-64944591 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040072 Approved Approved Cytosol Expressed in all smooth muscle: 69.9 -RP11-644F5.10 ENSG00000258311 12 55716036-55724703 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed adipose tissue: 9.8 -C17orf49 BAP18, HEPIS, MGC49942 ENSG00000258315 Chromosome 17 open reading frame 49 17 7014495-7017525 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022961, HPA024457 Supported Uncertain Nucleoplasm
Cytosol Expressed in all lymph node: 110.2 -RTEL1 bK3184A7.3, C20orf41, DKFZP434C013, KIAA1088, NHL, RTEL ENSG00000258366 Regulator of telomere elongation helicase 1 20 63657810-63696253 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA067329 Supported Nuclear bodies Expressed in all testis: 13.2 -ZNF578 FLJ31384 ENSG00000258405 Zinc finger protein 578 19 52453576-52512154 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 5 testis: 14.0 thyroid gland: 2.7 -RP11-240B13.2 ENSG00000258417 8 132024238-132085655 Predicted membrane proteins No evidence No evidence Not detected cerebral cortex: 0.1 -PDF ENSG00000258429 Peptide deformylase (mitochondrial) 16 69328621-69330595 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA063409 Approved Approved Nucleoplasm
Mitochondria Expressed in all kidney: 7.8 -RNASE12 RAI1 ENSG00000258436 Ribonuclease, RNase A family, 12 (non-active) 14 20590193-20590823 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044175 Uncertain Uncertain Vesicles
Microtubules Tissue enriched 255 epididymis: 1061.8 seminal vesicle: 4.1 -OR11H2 C14orf15, OR11H2P, OR11H8P ENSG00000258453 Olfactory receptor, family 11, subfamily H, member 2 14 19712936-19713920 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence HPA047370 Uncertain Not detected adipose tissue: 0.0 -RP11-574F21.3 ENSG00000258465 1 160217464-160285130 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA027218, HPA027381, HPA044837 Approved Approved Nucleoplasm
Cytosol Mixed smooth muscle: 2.3 -RP11-1012A1.4 ENSG00000258466 14 67659820-67690367 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected urinary bladder: 0.5 -RP11-192H23.4 ENSG00000258472 17 28455752-28614197 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA046590 Uncertain Approved Nucleoplasm
Vesicles
Plasma membrane Tissue enhanced 0 cerebral cortex: 2.2 lung: 1.2 -SPESP1 SP-ESP ENSG00000258484 Sperm equatorial segment protein 1 15 68818221-68946811 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045936, HPA051040 Supported Tissue enriched 7 testis: 127.6 placenta: 17.8 -RP11-108O10.8 ENSG00000258529 11 111786286-111879425 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA038575 Uncertain Approved Endoplasmic reticulum Tissue enhanced 0 testis: 1.7 skin: 0.9 -SPECC1L-ADORA2A ENSG00000258555 SPECC1L-ADORA2A readthrough (NMD candidate) 22 24270898-24442356 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 bone marrow: 15.0;lymph node: 15.2 appendix: 12.5 -TRIM6-TRIM34 ENSG00000258588 TRIM6-TRIM34 readthrough 11 5596725-5644398 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA077996 Approved Nucleoli
Centrosome Not detected testis: 0.6 -BCL2L2-PABPN1 ENSG00000258643 BCL2L2-PABPN1 readthrough 14 23306835-23325369 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA000637 Approved Approved Mixed seminal vesicle: 28.8 -SYNJ2BP-COX16 ENSG00000258644 SYNJ2BP-COX16 readthrough 14 70326064-70417074 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA000866, HPA062659 Approved Supported Approved Mitochondria Tissue enhanced 0 testis: 45.8 breast: 15.8 -TRIM34 RNF21 ENSG00000258659 Tripartite motif containing 34 11 5619764-5644398 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA077996 Approved Nucleoli
Centrosome Mixed spleen: 18.8 -CTC-260F20.3 ENSG00000258674 19 19516227-19536076 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Mixed cerebral cortex: 4.6 -RP11-404P21.8 ENSG00000258691 14 96204844-96263929 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed gallbladder: 1.4 -C20orf141 dJ860F19.4 ENSG00000258713 Chromosome 20 open reading frame 141 20 2814987-2815833 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 106 testis: 96.9 placenta: 0.9 -CTD-2135J3.4 ENSG00000258724 8 10725399-10839847 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA009065 Uncertain Approved Nuclear speckles
Golgi apparatus Not detected adipose tissue: 0.5 -RP11-195F19.29 ENSG00000258728 9 34646645-34657113 Predicted intracellular proteins No evidence No evidence Not detected fallopian tube: 0.3 -OR4C13 ENSG00000258817 Olfactory receptor, family 4, subfamily C, member 13 11 49952391-49953419 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -RNASE4 RAB1 ENSG00000258818 Ribonuclease, RNase A family, 4 14 20684100-20701215 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 liver: 231.7 prostate: 129.2 -ERCC6-PGBD3 ENSG00000258838 ERCC6-PGBD3 readthrough 10 49515201-49539538 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA025825 Approved Mixed parathyroid gland: 3.9 -MC1R MSH-R ENSG00000258839 Melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 16 89912119-89920977 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 12.8 skin: 6.0 -DUXA ENSG00000258873 Double homeobox A 19 57154021-57167443 Predicted intracellular proteins, Transcription factors No evidence No evidence No evidence HPA059358 Uncertain Not detected spleen: 0.3 -AC007040.11 ENSG00000258881 2 70939318-70995336 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 1.3 skin: 0.7 -CEP95 CCDC45, DKFZp667E1824 ENSG00000258890 Centrosomal protein 95kDa 17 64506588-64542461 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023654, HPA052426, HPA052428, HPA061371 Approved Approved Nucleoplasm
Centrosome
Cytosol Expressed in all endometrium: 27.7 -RP11-407N17.3 ENSG00000258941 14 39233902-39350423 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA000387, HPA000922, HPA054066, HPA055459 Uncertain Approved Endoplasmic reticulum Group enriched 5 duodenum: 16.1;kidney: 10.3;liver: 13.3;parathyroid gland: 21.0;small intestine: 19.1 gallbladder: 3.0 -TUBB3 beta-4, CFEOM3, CFEOM3A, FEOM3 ENSG00000258947 Tubulin, beta 3 class III 16 89921392-89938761 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043640, HPA046280 Approved Supported Microtubules Tissue enriched 6 cerebral cortex: 196.2 adrenal gland: 34.7 -RP11-934B9.3 ENSG00000258973 14 24332310-24337382 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA055087 Uncertain Not detected placenta: 0.5 -TMEM179 C14orf90, FLJ42486, TMEM179A ENSG00000258986 Transmembrane protein 179 14 104474678-104605647 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA002942 Uncertain Mitochondria Group enriched 8 adrenal gland: 14.7;cerebral cortex: 28.0 testis: 2.5 -RP11-47I22.4 ENSG00000258989 14 61529128-61657964 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed epididymis: 16.6 -TSPY1 CT78, TSPY ENSG00000258992 Testis specific protein, Y-linked 1 Y 9466955-9490081 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049384 Supported Tissue enriched 172 testis: 32.7 adipose tissue: 0.1 -TVP23C-CDRT4 FAM18B2-CDRT4 ENSG00000259024 TVP23C-CDRT4 readthrough 17 15436021-15563561 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA065603 Approved Golgi apparatus Mixed parathyroid gland: 11.6 -FPGT-TNNI3K ENSG00000259030 FPGT-TNNI3K readthrough 1 74198235-74543982 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA072331 Approved Vesicles Mixed heart muscle: 5.6 -RP11-14J7.7 ENSG00000259060 14 20582892-20609795 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Group enriched 35 epididymis: 5.6;testis: 1.4 adipose tissue: 0.0 -RP11-371E8.4 ENSG00000259066 14 93184973-93218586 Predicted intracellular proteins No evidence No evidence Not detected skeletal muscle: 0.2 -POC1B-GALNT4 ENSG00000259075 POC1B-GALNT4 readthrough 12 89519408-89526262 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA076116 Uncertain Golgi apparatus Mixed endometrium: 2.5 -NDUFC2-KCTD14 ENSG00000259112 NDUFC2-KCTD14 readthrough 11 78016971-78079865 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038873, HPA056195 Approved Supported Mitochondria Tissue enhanced 0 duodenum: 5.1 stomach: 2.6 -SMIM6 C17orf110 ENSG00000259120 Small integral membrane protein 6 17 75646243-75647977 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence HPA065721 Uncertain Approved Nucleus Tissue enhanced 0 fallopian tube: 39.8;stomach: 34.4 testis: 22.7 -RP11-298I3.5 ENSG00000259132 14 22946270-22982258 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA029803 Approved Approved Plasma membrane
Focal adhesion sites Mixed lymph node: 9.2 -RP11-903H12.5 ENSG00000259171 14 20684587-20700576 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Mixed ovary: 96.3 -ITGB3 CD61, GP3A, GPIIIa ENSG00000259207 Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 17 47253846-47311816 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027852 Supported Tissue enhanced 0 thyroid gland: 95.1 smooth muscle: 36.3 -SLC35G6 AMAC1L3, TMEM21B ENSG00000259224 Solute carrier family 35, member G6 17 7481332-7483496 Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 19 testis: 3.7 skeletal muscle: 0.1 -PAK6 ENSG00000259288 P21 protein (Cdc42/Rac)-activated kinase 6 15 40217428-40276396 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA031124 Uncertain Approved Nucleus
Nucleoli fibrillar center
Cell Junctions Not detected cerebral cortex: 0.1 -ZHX1-C8orf76 ENSG00000259305 ZHX1-C8orf76 readthrough 8 123226189-123274284 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023708 Uncertain Uncertain Nucleoplasm
Cytosol Mixed bone marrow: 5.3 -ST20-MTHFS ENSG00000259332 ST20-MTHFS readthrough 15 79845150-79923754 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA008067 Uncertain Mixed parathyroid gland: 15.3 -RP11-468E2.6 ENSG00000259371 14 24120956-24131829 Predicted membrane proteins No evidence No evidence Not detected testis: 0.5 -GH1 GH, GH-N, GHN, hGH-N ENSG00000259384 Growth hormone 1 17 63917200-63918838 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043715 Supported Tissue enhanced 0 placenta: 1.2 duodenum: 0.7 -TGIF2-C20orf24 ENSG00000259399 TGIF2-C20orf24 readthrough 20 36574553-36612384 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Mixed appendix: 11.9 -THTPA THTPASE ENSG00000259431 Thiamine triphosphatase 14 23555988-23560271 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028876 Approved Uncertain Nucleus
Nucleoli Expressed in all parathyroid gland: 32.8 -MRPL46 C15orf4, LIECG2, P2ECSL ENSG00000259494 Mitochondrial ribosomal protein L46 15 88459476-88467419 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050166 Uncertain Supported Nucleoplasm
Cell Junctions
Mitochondria Expressed in all adrenal gland: 50.5 -UBE2Q2L ENSG00000259511 Ubiquitin-conjugating enzyme E2Q family member 2-like 15 84172490-84182234 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 testis: 16.0 ovary: 5.6 -RP11-468E2.2 ENSG00000259522 14 24180395-24190416 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 colon: 1.0 stomach: 0.4 -BLID BRCC2 ENSG00000259571 BH3-like motif containing, cell death inducer 11 122115354-122116215 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Not detected adipose tissue: 0.0 -RP11-812E19.9 ENSG00000259680 16 33844784-33845229 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 tonsil: 23.0 urinary bladder: 12.7 -AC066615.1 ENSG00000259752 15 47133652-47134026 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 endometrium: 2.1;urinary bladder: 1.7 esophagus: 1.4 -RP11-20I23.3 ENSG00000259784 16 2513965-2527955 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 bone marrow: 1.1;small intestine: 1.4 smooth muscle: 0.5 -SLC22A31 ENSG00000259803 Solute carrier family 22, member 31 16 89195761-89201664 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enriched 7 lung: 23.1 pancreas: 3.4 -LYPD8 ENSG00000259823 LY6/PLAUR domain containing 8 1 248718649-248755739 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Group enriched 12 colon: 220.5;rectum: 143.8 appendix: 15.1 -RP11-407P15.2 ENSG00000259916 2 94588522-94604573 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enriched 11 adipose tissue: 6.1 kidney: 0.5 -RBM15B HUMAGCGB, OTT3 ENSG00000259956 RNA binding motif protein 15B 3 51391268-51397908 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036645, HPA058136 Approved Validated Nucleoplasm Expressed in all parathyroid gland: 21.2 -TGFBR3L ENSG00000260001 Transforming growth factor, beta receptor III-like 19 7916145-7919097 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA074356 Approved Vesicles Tissue enhanced 0 duodenum: 1.8;small intestine: 1.8 kidney: 1.2 -RP11-315D16.2 ENSG00000260007 15 68193801-68229718 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected liver: 0.8 -HOXB7 HOX2, HOX2C ENSG00000260027 Homeobox B7 17 48607227-48633572 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA049940 Uncertain Supported Nucleoplasm
Nuclear bodies
Cytosol Tissue enhanced 0 epididymis: 161.9 cervix: 32.9 -SPDYE6 ENSG00000260097 Speedy/RINGO cell cycle regulator family member E6 7 102347206-102356444 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA044799, HPA051750 Uncertain Mixed testis: 6.9 -RP11-96O20.4 ENSG00000260170 15 45587351-45676314 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA041589 Uncertain Not detected colon: 0.7 -CCDC187 MGC50722 ENSG00000260220 Coiled-coil domain containing 187 9 136280942-136306901 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Group enriched 5 fallopian tube: 10.9;testis: 14.3;thyroid gland: 3.1 seminal vesicle: 1.7 -FRRS1L C9orf4, CG-6 ENSG00000260230 Ferric-chelate reductase 1-like 9 109130293-109167291 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA071086 Supported Tissue enhanced 0 cerebral cortex: 47.9 ovary: 14.1 -PMF1-BGLAP ENSG00000260238 PMF1-BGLAP readthrough 1 156212982-156243332 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA034583, HPA071854 Supported Nucleoplasm
Vesicles Mixed fallopian tube: 8.1 -RP11-20I23.1 ENSG00000260272 16 2496032-2520218 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA044712 Uncertain Not detected bone marrow: 0.5 -C6orf229 ENSG00000260286 Chromosome 6 open reading frame 229 6 24797321-24798889 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 13 testis: 22.0 lung: 1.7 -TBC1D3G ENSG00000260287 TBC1 domain family, member 3G 17 36323884-36334759 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046969, HPA047745, HPA052553 Uncertain Approved Vesicles Tissue enriched 60 testis: 6.0 adipose tissue: 0.0 -RP11-505K9.4 ENSG00000260300 16 83908132-83951445 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed heart muscle: 2.3 -MRC1 bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1 ENSG00000260314 Mannose receptor, C type 1 10 17809344-17911170 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA004114, HPA045134, CAB068203 Supported Tissue enhanced 0 lung: 180.0 placenta: 76.9 -HSPB9 CT51 ENSG00000260325 Heat shock protein, alpha-crystallin-related, B9 17 42121431-42123352 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 11 testis: 6.8 liver: 0.6 -RP11-1035H13.3 ENSG00000260342 16 18788063-18801519 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA045307 Uncertain Approved Endoplasmic reticulum Tissue enhanced 0 testis: 25.7 cerebral cortex: 7.2 -RP11-343C2.9 ENSG00000260371 16 69335091-69356306 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed testis: 2.2 -SCX bHLHa41, bHLHa48, SCXA, SCXB ENSG00000260428 Scleraxis bHLH transcription factor 8 144266560-144268481 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level No evidence HPA043183 Uncertain Tissue enhanced 0 skeletal muscle: 5.3 parathyroid gland: 3.3 -C16orf95 ENSG00000260456 Chromosome 16 open reading frame 95 16 87083562-87317420 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA040850, HPA067924 Supported Approved Endoplasmic reticulum Tissue enriched 25 testis: 80.4 cerebral cortex: 3.2 -KCNJ18 KIR2.6, TTPP2 ENSG00000260458 Potassium channel, inwardly rectifying subfamily J, member 18 17 21692523-21704612 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA027021 Uncertain Uncertain Nucleoplasm
Golgi apparatus
Cytosol Group enriched 8 skin: 3.9;tonsil: 1.3 testis: 0.3 -RP11-529K1.3 ENSG00000260537 16 70299194-70372582 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA046380, HPA066668 Approved Uncertain Nucleoplasm Mixed urinary bladder: 7.4 -RP6-24A23.6 ENSG00000260548 X 108722070-108732687 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 ovary: 12.8;thyroid gland: 12.4 endometrium: 5.6 -DUX4 ENSG00000260596 Double homeobox 4 4 190173774-190185942 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA058451 Approved Nucleus
Nucleoli
Cytosol Tissue enhanced 0 testis: 1.5 seminal vesicle: 0.5 -ANKRD20A1 ANKRD20A, DKFZp434A171 ENSG00000260691 Ankyrin repeat domain 20 family, member A1 9 67859147-67902094 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043239, HPA047112, HPA047167, HPA047766, HPA051753 Uncertain Tissue enriched 7 testis: 5.1 spleen: 0.7 -RP11-152F13.10 ENSG00000260836 15 82540032-82555932 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected cerebral cortex: 0.2 -RP4-576H24.4 ENSG00000260861 20 1540144-1620009 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 appendix: 3.3;cerebral cortex: 4.5 testis: 2.6 -AC002310.13 ENSG00000260869 16 30534227-30558279 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected adipose tissue: 0.5 -XKR7 C20orf159, dJ310O13.4 ENSG00000260903 XK, Kell blood group complex subunit-related family, member 7 20 31968002-32003387 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA040854 Uncertain Tissue enriched 10 cerebral cortex: 3.6 testis: 0.3 -RP11-343C2.11 ENSG00000260914 16 69299682-69322700 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA060092 Uncertain Midbody Expressed in all cerebral cortex: 85.5 -CCPG1 CPR8, KIAA1254 ENSG00000260916 Cell cycle progression 1 15 55340032-55408510 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009432, HPA026861 Approved Approved Endoplasmic reticulum
Golgi apparatus Expressed in all thyroid gland: 139.9 -SULT1A3 STM, TL-PST ENSG00000261052 Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 16 30199228-30204310 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA049500, HPA051051 Supported Expressed in all duodenum: 109.2 -TMEM178B DKFZp547G036 ENSG00000261115 Transmembrane protein 178B 7 141074232-141480380 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA048771 Uncertain Uncertain Nucleoli
Vesicles Tissue enhanced 0 cerebral cortex: 19.4;parathyroid gland: 28.5;thyroid gland: 14.3 heart muscle: 7.4 -RP11-1021N1.1 ENSG00000261130 16 15395754-15515348 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -EPPK1 EPIPL1 ENSG00000261150 Epiplakin 1 8 143857324-143878464 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA066808, HPA067357, HPA069333 Approved Validated Intermediate filaments Tissue enhanced 0 skin: 11.2 small intestine: 3.0 -CLEC19A ENSG00000261210 C-type lectin domain family 19, member A 16 19285739-19322145 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042113 Uncertain Tissue enriched 6 cerebral cortex: 2.6 skin: 0.4 -ZNF865 ENSG00000261221 Zinc finger protein 865 19 55605405-55617269 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA068079 Approved Nucleus
Nucleoli Mixed skeletal muscle: 8.4 -BOP1 KIAA0124 ENSG00000261236 Block of proliferation 1 8 144262102-144291370 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047869, HPA066764 Approved Validated Nucleus
Nucleoli Expressed in all appendix: 25.1 -GOLGA8T ENSG00000261247 Golgin A8 family, member T 15 30135149-30145567 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 10 testis: 7.2 thyroid gland: 0.7 -MUC22 PBMUCL1 ENSG00000261272 Mucin 22 6 31010474-31035402 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 117 esophagus: 20.3 tonsil: 0.1 -PECAM1 CD31 ENSG00000261371 Platelet/endothelial cell adhesion molecule 1 17 64319415-64413776 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA004690 Supported Expressed in all placenta: 654.4 -TEN1-CDK3 ENSG00000261408 TEN1-CDK3 readthrough (NMD candidate) 17 75979231-76005999 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA007420 Uncertain Approved Cytosol Tissue enhanced 0 cervix, uterine: 1.9;testis: 2.0 salivary gland: 0.4 -TUBB8 bA631M21.2 ENSG00000261456 Tubulin, beta 8 class VIII 10 46892-74163 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043640, HPA046280 Uncertain Approved Microtubules Tissue enhanced 0 testis: 1.1 parathyroid gland: 0.8 -TP53TG3B ENSG00000261509 TP53 target 3B 16 33360274-33363478 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 15 epididymis: 21.9 testis: 1.4 -TMEM249 C8orfK29 ENSG00000261587 Transmembrane protein 249 8 144352219-144354914 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 27 testis: 9.4 epididymis: 0.3 -TPBGL ENSG00000261594 Trophoblast glycoprotein-like 11 75240905-75243697 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 cerebral cortex: 3.1;testis: 5.0 adrenal gland: 2.3 -PRSS46 TESSP6 ENSG00000261603 Protease, serine, 46 3 46719583-46736429 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 epididymis: 4.4;testis: 8.4 parathyroid gland: 2.7 -GAN GAN1, KLHL16 ENSG00000261609 Gigaxonin 16 81314952-81390884 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011825, HPA049473 Approved Supported Microtubules Tissue enriched 6 skin: 29.6 cerebral cortex: 5.0 -C15orf65 FLJ27352 ENSG00000261652 Chromosome 15 open reading frame 65 15 55408548-55418764 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA067189 Approved Approved Nucleus
Cytosol Mixed testis: 16.8 -RP11-520P18.5 ENSG00000261667 8 143080457-143083001 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 1.1 seminal vesicle: 0.7 -SCRT1 DKFZp547F072, ZNF898 ENSG00000261678 Scratch family zinc finger 1 8 144330565-144336281 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA045265 Uncertain Approved Nuclear bodies Tissue enriched 7 cerebral cortex: 10.9 adrenal gland: 1.5 -HPR ENSG00000261701 Haptoglobin-related protein 16 72063224-72077246 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047750 Supported Approved Vesicles Tissue enriched 29 liver: 443.2 heart muscle: 15.4 -RP11-77K12.1 ENSG00000261717 16 75412684-75464706 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA041316, HPA055071 Uncertain Not detected testis: 0.8 -GOLGA8S ENSG00000261739 Golgin A8 family, member S 15 23354748-23367231 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.7 -RP11-345J4.5 ENSG00000261740 16 29443230-29454651 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Expressed in all lymph node: 18.0 -TCF24 bHLHa25 ENSG00000261787 Transcription factor 24 8 66946501-66962590 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 kidney: 1.2;testis: 2.9 fallopian tube: 0.8 -RP11-350O14.18 ENSG00000261793 9 137168854-137171984 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Group enriched 7 prostate: 14.5;salivary gland: 23.2 small intestine: 2.9 -GOLGA8H GOLGA6L11 ENSG00000261794 Golgin A8 family, member H 15 30604126-30614561 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 testis: 8.5 fallopian tube: 2.1 -ISY1-RAB43 ENSG00000261796 ISY1-RAB43 readthrough 3 129087575-129161036 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA006312, HPA016995 Approved Validated Nuclear speckles Expressed in all parathyroid gland: 13.9 -MIA CD-RAP ENSG00000261857 Melanoma inhibitory activity 19 40771648-40777490 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031950 Supported Tissue enhanced 0 breast: 62.4;stomach: 51.0 salivary gland: 18.6 -PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 Protocadherin gamma subfamily A, 9 5 141402932-141512979 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA008755 Uncertain Tissue enhanced 0 cerebral cortex: 9.6 endometrium: 4.1 -GFY Goofy ENSG00000261949 Golgi-associated, olfactory signaling regulator 19 49423749-49428818 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 testis: 1.0 cerebral cortex: 0.2 -OCLM ENSG00000262180 Oculomedin 1 186400572-186401455 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed epididymis: 2.4 -PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 Protocadherin gamma subfamily B, 3 5 141370264-141512979 Plasma proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755, HPA035823 Uncertain Mixed endometrium: 1.5 -CORO7 FLJ22021 ENSG00000262246 Coronin 7 16 4354542-4425705 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041657, HPA053586 Uncertain Mixed bone marrow: 24.5 -MMP12 HME ENSG00000262406 Matrix metallopeptidase 12 11 102862736-102875034 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 appendix: 55.9;urinary bladder: 29.8 tonsil: 17.9 -CCER2 ENSG00000262484 Coiled-coil glutamate-rich protein 2 19 38908980-38912158 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level HPA069716 Uncertain Tissue enhanced 0 skin: 3.3 testis: 1.2 -PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 Protocadherin gamma subfamily A, 4 5 141355025-141512979 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA008755 Uncertain Mixed cerebral cortex: 5.7 -LA16c-306E5.2 ENSG00000262621 16 3365099-3479550 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cervix, uterine: 1.3 appendix: 1.0 -OR1D5 OR17-31 ENSG00000262628 Olfactory receptor, family 1, subfamily D, member 5 17 3062669-3063607 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected epididymis: 0.0 -SPON1 f-spondin, KIAA0762 ENSG00000262655 Spondin 1, extracellular matrix protein 11 13962689-14267884 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 gallbladder: 168.2 fallopian tube: 103.7 -RP13-1032I1.10 ENSG00000262660 17 81703371-81720539 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA022853, HPA023043, HPA023048 Approved Validated Mitochondria Tissue enhanced 0 cerebral cortex: 1.1;duodenum: 2.1 small intestine: 0.8 -OVCA2 ENSG00000262664 Ovarian tumor suppressor candidate 2 17 2041936-2043430 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059002 Approved Nucleoplasm
Cytosol Expressed in all gallbladder: 34.3 -MRPL12 MRPL7, MRPL7/L12, RPML12 ENSG00000262814 Mitochondrial ribosomal protein L12 17 81703357-81707526 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022853, HPA023043 Supported Supported Mitochondria Expressed in all skeletal muscle: 57.3 -C19orf84 ENSG00000262874 Chromosome 19 open reading frame 84 19 51388289-51390574 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA068082 Approved Tissue enriched 54 testis: 24.6 bone marrow: 0.4 -FAM58A FLJ21610, MGC29729 ENSG00000262919 Family with sequence similarity 58, member A X 153587919-153600045 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA050137, HPA059843 Uncertain Approved Nucleoplasm
Cytosol Expressed in all cerebral cortex: 15.3 -GTF2I BAP-135, BTKAP1, DIWS, IB291, SPIN, TFII-I, WBSCR6 ENSG00000263001 General transcription factor IIi 7 74657667-74760692 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004595, HPA026638 Supported Validated Nucleoplasm Expressed in all parathyroid gland: 227.9 -ZNF234 HZF4, ZNF269 ENSG00000263002 Zinc finger protein 234 19 44141557-44160309 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA001664 Approved Approved Nuclear bodies Mixed parathyroid gland: 9.1 -XXbac-BPG32J3.22 ENSG00000263020 6 31666102-31673546 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA005944, HPA048307 Uncertain Tissue enriched 20 bone marrow: 6.6 cerebral cortex: 0.3 -MYZAP GCOM1, Gup, Gup1, MYOZAP ENSG00000263155 Myocardial zonula adherens protein 15 57591941-57685364 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039827 Approved Tissue enhanced 0 heart muscle: 398.6 placenta: 83.5 -CTC-479C5.6 ENSG00000263201 16 68013436-68015911 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Group enriched 8 placenta: 1.2;testis: 3.1 bone marrow: 0.2 -CTB-133G6.1 ENSG00000263264 19 7348943-7383385 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA049151 Uncertain Tissue enhanced 0 lymph node: 22.6;spleen: 16.8 appendix: 16.0 -PPIAL4A COAS2, PPIAL4, PPIAL4B ENSG00000263353 Peptidylprolyl isomerase A (cyclophilin A)-like 4A 1 120889746-120890405 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058345 Uncertain Not detected cerebral cortex: 0.4 -PPIAL4C ENSG00000263464 Peptidylprolyl isomerase A (cyclophilin A)-like 4C 1 149583865-149584464 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058345 Uncertain Mixed duodenum: 4.0 -SRSF8 SFRS2B, SRP46 ENSG00000263465 Serine/arginine-rich splicing factor 8 11 95067197-95071224 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049905 Supported Supported Nucleus
Cytosol Expressed in all thyroid gland: 44.5 -FAM72C RP5-998N21.9 ENSG00000263513 Family with sequence similarity 72, member C 1 143955364-143971965 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA043271, HPA067321 Uncertain Approved Vesicles
Plasma membrane
Cytosol Tissue enhanced 0 lymph node: 5.6;tonsil: 4.4 testis: 3.0 -IKBKE IKK-i, IKKE, KIAA0151 ENSG00000263528 Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 1 206470476-206496889 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015788, CAB025983 Approved Supported Cytosol Mixed lymph node: 27.8 -RP11-599B13.6 ENSG00000263620 17 8150816-8162975 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 colon: 5.3;spleen: 5.3;stomach: 4.6 adipose tissue: 3.8 -MSMB IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94 ENSG00000263639 Microseminoprotein, beta- 10 46033307-46046269 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026357, HPA051257 Supported Tissue enriched 32 prostate: 18712.1 stomach: 590.2 -CRHR1 ENSG00000263715 Corticotropin releasing hormone receptor 1 17 45620344-45835826 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enriched 9 cerebral cortex: 1.1 fallopian tube: 0.1 -GDF2 BMP-9, BMP9 ENSG00000263761 Growth differentiation factor 2 10 47322490-47326270 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB023357 Uncertain Tissue enriched 61 liver: 11.3 testis: 0.1 -NBPF11 NBPF24 ENSG00000263956 Neuroblastoma breakpoint family, member 11 1 148102046-148152322 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Expressed in all epididymis: 20.4 -C1orf186 FLJ16052 ENSG00000263961 Chromosome 1 open reading frame 186 1 206037231-206102459 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cervix, uterine: 37.8 seminal vesicle: 28.6 -ANXA8L1 ANXA8L2, bA145E20.2, bA301J7.3 ENSG00000264230 Annexin A8-like 1 10 46375627-46537864 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA045246, HPA047451 Approved Nucleoplasm Group enriched 7 esophagus: 200.1;skin: 461.5 urinary bladder: 45.9 -NOTCH2NL N2N ENSG00000264343 Notch 2 N-terminal like 1 146146203-146229026 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB004669, HPA046392 Uncertain Expressed in all testis: 41.4 -DYNLL2 Dlc2, DNCL1B, MGC17810, RSPH22 ENSG00000264364 Dynein, light chain, LC8-type 2 17 58083415-58095536 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039954 Uncertain Nucleoplasm
Nuclear bodies
Cytosol Expressed in all cerebral cortex: 95.3 -MYH4 MYH2B, MyHC-2B, MyHC-IIb ENSG00000264424 Myosin, heavy chain 4, skeletal muscle 17 10443290-10469559 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001349 Supported Tissue enriched 18 skeletal muscle: 3.6 testis: 0.1 -OTUD7B CEZANNE, ZA20D1 ENSG00000264522 OTU deubiquitinase 7B 1 149937812-150010676 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027045 Supported Approved Nucleoplasm
Microtubules Mixed testis: 23.5 -RP13-582O9.6 ENSG00000264668 8 143247110-143276403 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA047232, HPA056268 Uncertain Uncertain Nucleus
Nucleoli Mixed fallopian tube: 1.0 -GJA5 CX40 ENSG00000265107 Gap junction protein, alpha 5, 40kDa 1 147756199-147773362 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013080 Uncertain Tissue enhanced 0 placenta: 122.1 lung: 39.9 -CTD-2370N5.3 ENSG00000265118 17 31305213-31318831 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA045033 Uncertain Tissue enhanced 0 appendix: 5.3 tonsil: 3.2 -ANXA8 ANX8 ENSG00000265190 Annexin A8 10 47460162-47484158 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045246, HPA047451 Approved Nucleoplasm Tissue enhanced 0 esophagus: 230.0;skin: 370.0 urinary bladder: 66.5 -RBP3 D10S64, D10S65, D10S66, RP66 ENSG00000265203 Retinol binding protein 3, interstitial 10 47348371-47357875 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041301, HPA044239 Supported Not detected duodenum: 0.4 -RBM8A BOV-1A, BOV-1B, BOV-1C, RBM8, RBM8B, Y14, ZNRP ENSG00000265241 RNA binding motif protein 8A 1 145917714-145927678 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018403 Supported Validated Nuclear speckles Expressed in all esophagus: 162.1 -CTD-2510F5.6 ENSG00000265303 17 59197566-59215226 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected tonsil: 0.6 -TIMM23 TIM23 ENSG00000265354 Translocase of inner mitochondrial membrane 23 homolog (yeast) 10 45972449-46003734 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031408 Approved Supported Mitochondria Expressed in all testis: 141.6 -RNF115 CL469780, ZNF364 ENSG00000265491 Ring finger protein 115 1 145738868-145824077 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA019130 Approved Approved Nucleoli
Mitochondria Mixed smooth muscle: 16.3 -AP000275.65 ENSG00000265590 21 32578822-32612281 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA019055, HPA028849 Approved Supported Mixed testis: 25.8 -RPL17 L17, rpL23 ENSG00000265681 Ribosomal protein L17 18 49488453-49492523 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043724, HPA046385 Supported Supported Endoplasmic reticulum
Cytosol Expressed in all ovary: 4386.6 -ZNF488 FLJ32104 ENSG00000265763 Zinc finger protein 488 10 47365496-47384273 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035957, HPA035958, HPA044867 Uncertain Supported Nucleoplasm
Cytosol Group enriched 7 cerebral cortex: 19.1;duodenum: 23.2;placenta: 4.7;small intestine: 12.4 skin: 2.0 -SEC22B ERS-24, sec22b, SEC22L1 ENSG00000265808 SEC22 homolog B, vesicle trafficking protein (gene/pseudogene) 1 120150898-120176515 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all epididymis: 42.7 -FSBP ENSG00000265817 Fibrinogen silencer binding protein 8 94378377-94436952 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA025059, HPA026509 Approved Supported Nucleus Mixed seminal vesicle: 3.1 -TXNIP EST01027, HHCPA78, THIF, VDUP1 ENSG00000265972 Thioredoxin interacting protein 1 145992435-145996600 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA031085, HPA053694 Approved Approved Plasma membrane
Cytosol Expressed in all adipose tissue: 1573.3 -SRGAP2 ARHGAP34, FNBP2, KIAA0456, SRGAP2A ENSG00000266028 SLIT-ROBO Rho GTPase activating protein 2 1 206203345-206464443 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA028191, HPA028196 Approved Supported Nucleoplasm
Cytosol Expressed in all parathyroid gland: 54.3 -BAHCC1 BAHD2, KIAA1447 ENSG00000266074 BAH domain and coiled-coil containing 1 17 81395475-81466332 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA023386, HPA076910 Uncertain Uncertain Nucleoli Mixed cerebral cortex: 4.8 -RP11-159D12.5 ENSG00000266086 17 57989038-58005253 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed skin: 17.9 -RASSF5 Maxp1, NORE1, RAPL ENSG00000266094 Ras association (RalGDS/AF-6) domain family member 5 1 206507530-206589283 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA070480 Approved Mixed spleen: 77.9 -STRADA LYK5, NY-BR-96, Stlk, STRAD ENSG00000266173 STE20-related kinase adaptor alpha 17 63702832-63741970 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031637 Approved Supported Nucleoplasm
Cytosol Expressed in all testis: 68.8 -RP1-66C13.4 ENSG00000266202 17 27798806-27893365 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA023051 Uncertain Tissue enhanced 0 ovary: 1.1 cerebral cortex: 0.7 -KLF14 BTEB5 ENSG00000266265 Kruppel-like factor 14 7 130731235-130734061 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA044729 Uncertain Tissue enhanced 0 placenta: 1.1 adipose tissue: 0.7 -RP11-219A15.1 ENSG00000266302 17 16690261-16804453 Predicted intracellular proteins No evidence No evidence HPA047220, HPA047851 Uncertain Approved Nucleoplasm
Vesicles Not detected adipose tissue: 0.0 -NBPF15 MGC8902, NBPF16 ENSG00000266338 Neuroblastoma breakpoint family, member 15 1 144421386-144461674 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Expressed in all epididymis: 24.7 -NCOA4 ARA70, DKFZp762E1112, ELE1, PTC3, RFG ENSG00000266412 Nuclear receptor coactivator 4 10 46005088-46030714 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA051260, HPA065208 Uncertain Approved Nucleoli
Golgi apparatus
Cytosol Expressed in all duodenum: 253.9 -MRPS21 ENSG00000266472 Mitochondrial ribosomal protein S21 1 150293720-150308979 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA078289 Approved Mitochondria Expressed in all adrenal gland: 74.2 -GDF10 BMP-3b ENSG00000266524 Growth differentiation factor 10 10 47300386-47313547 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA015498 Uncertain Tissue enhanced 0 lung: 19.6 testis: 9.0 -MYO15B MYO15BP ENSG00000266714 Myosin XVB 17 75588058-75626501 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA022857, HPA023105 Approved Cytosol Expressed in all duodenum: 152.7 -TBC1D29 DKFZP434O047 ENSG00000266733 TBC1 domain family, member 29 17 30557112-30563493 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA059178 Uncertain Tissue enriched 11 testis: 10.6 epididymis: 0.9 -RP11-618P17.4 ENSG00000266953 19 34396315-34409364 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skeletal muscle: 3.0 stomach: 0.7 -FXYD1 PLM ENSG00000266964 FXYD domain containing ion transport regulator 1 19 35138808-35143109 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA026873 Approved Nucleus
Nucleoli
Cytosol Expressed in all skeletal muscle: 469.2 -AARSD1 MGC2744 ENSG00000266967 Alanyl-tRNA synthetase domain containing 1 17 42950526-42964498 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA021408, HPA022869, HPA023714 Supported Approved Nuclear membrane
Cytosol Expressed in all testis: 99.0 -AC006538.4 ENSG00000267001 19 2717769-2740048 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA058526 Uncertain Mixed testis: 3.9 -ZNF850 ZNF850P ENSG00000267041 Zinc finger protein 850 19 36714383-36772825 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA029299 Uncertain Approved Nucleoplasm Mixed testis: 5.0 -PTGES3L ENSG00000267060 Prostaglandin E synthase 3 (cytosolic)-like 17 42968088-42980433 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 heart muscle: 28.3;skeletal muscle: 58.7 smooth muscle: 16.3 -RP11-322E11.6 ENSG00000267140 18 35443871-35497940 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed lymph node: 5.3 -CTB-54O9.9 ENSG00000267157 19 5784005-5785619 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed testis: 1.0 -RP11-318A15.7 ENSG00000267168 17 76732978-76738522 Predicted intracellular proteins No evidence No evidence Not detected bone marrow: 0.1 -CTC-512J12.6 ENSG00000267173 19 44329695-44401608 Predicted intracellular proteins No evidence No evidence Not detected duodenum: 0.3 -CTD-2006C1.13 ENSG00000267179 19 11925075-11979290 Predicted intracellular proteins No evidence No evidence HPA047845 Uncertain Uncertain Nucleus Not detected testis: 0.5 -LCN6 ENSG00000267206 Lipocalin 6 9 136744011-136748528 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 221 epididymis: 1869.1 smooth muscle: 8.4 -CTD-2132N18.3 ENSG00000267261 17 42119674-42154916 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected appendix: 0.8 -RP11-793H13.10 ENSG00000267281 12 53506688-53625979 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA003384 Uncertain Approved Nucleus
Cytosol Not detected lung: 0.7 -RP11-178C3.1 ENSG00000267318 17 59940908-59973101 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed testis: 11.3 -CTB-60B18.6 ENSG00000267335 19 49022953-49036895 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA038925 Uncertain Approved Cytosol Not detected testis: 0.8 -CTC-454I21.3 ENSG00000267360 19 37093019-37210512 Predicted intracellular proteins No evidence No evidence Not detected thyroid gland: 0.9 -UPK3BL UPLP ENSG00000267368 Uroplakin 3B-like 7 102637025-102642791 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA011403 Supported Expressed in all esophagus: 139.3 -APOC4 ENSG00000267467 Apolipoprotein C-IV 19 44942238-44945496 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062671 Approved Tissue enriched 154 liver: 344.8 testis: 2.2 -ZNF285 ZNF285A ENSG00000267508 Zinc finger protein 285 19 44382298-44401608 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level HPA046100, HPA049212 Uncertain Mixed ovary: 7.8 -S1PR2 AGR16, EDG5, Gpcr13, H218 ENSG00000267534 Sphingosine-1-phosphate receptor 2 19 10221435-10231272 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA014307 Approved Tissue enhanced 0 placenta: 26.9 lymph node: 13.5 -RP5-1052I5.2 ENSG00000267561 1 86993009-87169204 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA043069, HPA043603 Uncertain Uncertain Mitochondria Tissue enhanced 0 adipose tissue: 21.9 breast: 8.8 -RAD51L3-RFFL ENSG00000267618 17 35011349-35121493 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 4.2 cerebral cortex: 1.6 -CGB1 ENSG00000267631 Chorionic gonadotropin, beta polypeptide 1 19 49035610-49036895 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA038925, HPA038934 Supported Approved Cytosol Not detected pancreas: 0.6 -FDX1L MGC19604 ENSG00000267673 Ferredoxin 1-like 19 10310045-10316015 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043986 Approved Expressed in all cerebral cortex: 47.5 -ZNF224 BMZF-2, KOX22, ZNF255, ZNF27 ENSG00000267680 Zinc finger protein 224 19 44094339-44109886 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level HPA054045 Approved Supported Nucleus
Nuclear membrane Expressed in all spleen: 36.1 -LUZP6 MPD6, MTPNUT ENSG00000267697 Leucine zipper protein 6 7 135927274-135927450 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA077907 Approved Lipid droplets Not detected skeletal muscle: 0.1 -AC024592.12 ENSG00000267740 19 5866171-5903787 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level HPA072209 Uncertain Mitochondria Mixed adrenal gland: 1.5 -CTB-102L5.4 ENSG00000267748 19 38289151-38304910 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 salivary gland: 5.5 thyroid gland: 2.9 -SMIM22 ENSG00000267795 Small integral membrane protein 22 16 4788397-4796491 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA077331 Approved Nucleoplasm
Cytosol Mixed colon: 229.8 -LIN37 F25965, lin-37, ZK418.4 ENSG00000267796 Lin-37 DREAM MuvB core complex component 19 35748361-35754519 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043253, HPA047809 Uncertain Supported Nucleoplasm Expressed in all ovary: 12.4 -NDUFA7 B14.5a ENSG00000267855 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 19 8308768-8321396 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059251, HPA071866 Supported Supported Mitochondria Expressed in all heart muscle: 67.3 -AC011513.3 ENSG00000267881 19 41708612-41761282 Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA011041 Approved Group enriched 7 colon: 42.9;esophagus: 10.4 appendix: 3.7 -CCDC177 C14orf162, PLPL ENSG00000267909 Coiled-coil domain containing 177 14 69569816-69574837 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 2.3 epididymis: 0.7 -CTD-2207O23.12 ENSG00000267952 19 7507052-7519622 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 7.9;skeletal muscle: 5.8 kidney: 2.9 -MAGEA9B ENSG00000267978 Melanoma antigen family A9B X 149581653-149587453 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045401 Approved Golgi apparatus Tissue enriched 36 testis: 17.3 placenta: 0.4 -SSX4 CT5.4 ENSG00000268009 Synovial sarcoma, X breakpoint 4 X 48383516-48393347 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045683 Approved Tissue enriched 15 testis: 3.8 fallopian tube: 0.2 -NBPF12 COAS1, KIAA1245 ENSG00000268043 Neuroblastoma breakpoint family, member 12 1 146938744-146996202 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Expressed in all parathyroid gland: 19.6 -AC104534.3 ENSG00000268083 19 38817471-38840178 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA002907, HPA051748 Uncertain Not detected lung: 0.9 -GABRQ THETA ENSG00000268089 Gamma-aminobutyric acid (GABA) A receptor, theta X 152638183-152657534 FDA approved drug targets, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA002063 Uncertain Tissue enhanced 0 cerebral cortex: 6.6;cervix, uterine: 12.8 adrenal gland: 3.0 -SLC6A14 ENSG00000268104 Solute carrier family 6 (amino acid transporter), member 14 X 116436622-116461458 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA003193 Uncertain Approved Vesicles Tissue enhanced 0 cervix, uterine: 11.0;lung: 23.9 breast: 9.2 -AC003002.4 ENSG00000268133 19 57363566-57398584 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.2 -AC004076.9 ENSG00000268163 19 57437970-57477536 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed cerebral cortex: 1.0 -SMIM17 ENSG00000268182 Small integral membrane protein 17 19 56643145-56655766 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA071857, HPA071861 Supported Approved Vesicles Tissue enhanced 0 cerebral cortex: 8.7 epididymis: 2.0 -AC118758.1 ENSG00000268187 7 56804059-56804689 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 6 testis: 2.1 endometrium: 0.3 -OPN1MW CBBM, CBD, COD5, GCP, OPN1MW1 ENSG00000268221 Opsin 1 (cone pigments), medium-wave-sensitive X 154182596-154196135 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected appendix: 0.2 -ARL14EPL ENSG00000268223 ADP-ribosylation factor-like 14 effector protein-like 5 116032324-116060118 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Not detected testis: 0.4 -SCGB1C2 ENSG00000268320 Secretoglobin, family 1C, member 2 17 137526-139067 Predicted secreted proteins No evidence No evidence No evidence Not detected testis: 0.3 -FAM156A PRO0659, TMEM29 ENSG00000268350 Family with sequence similarity 156, member A X 52926402-52995472 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA056640, HPA056643 Approved Expressed in all skin: 63.2 -L34079.2 ENSG00000268361 19 43554692-43593036 Predicted intracellular proteins No evidence No evidence Not detected parathyroid gland: 0.5 -AC011530.4 ENSG00000268434 19 45779437-45785973 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 appendix: 1.0 epididymis: 0.7 -SSX2B CT5.2b ENSG00000268447 Synovial sarcoma, X breakpoint 2B X 52751132-52790305 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA045683 Supported Approved Nucleus
Nucleoli Tissue enriched 22 testis: 14.9 thyroid gland: 0.6 -CTC-273B12.7 ENSG00000268465 19 48465837-48472431 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 colon: 1.2;endometrium: 1.3;testis: 2.8 small intestine: 0.6 -AC018755.18 ENSG00000268500 19 51612091-51646889 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA009085 Approved Group enriched 5 appendix: 7.3;bone marrow: 14.2;lymph node: 3.6;spleen: 5.0 urinary bladder: 1.4 -AC004076.7 ENSG00000268533 19 57394183-57438457 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed skin: 8.9 -MAGEA2 CT1.2, MAGE2, MAGEA2A ENSG00000268606 Melanoma antigen family A2 X 152749863-152753884 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 54 testis: 6.9 cerebral cortex: 0.1 -TEX13A ENSG00000268629 Testis expressed 13A X 105218929-105220674 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 80 testis: 7.9 adipose tissue: 0.0 -AC006486.9 ENSG00000268643 19 42234583-42255132 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 7.8 endometrium: 5.1 -CTAG1A ESO1, LAGE2A ENSG00000268651 Cancer/testis antigen 1A X 154585143-154586821 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB013061 Supported Tissue enriched 39 testis: 4.6 spleen: 0.1 -FAM231B ENSG00000268674 Family with sequence similarity 231, member B Unmapped 35407-35916 Predicted intracellular proteins No evidence No evidence No evidence HPA043267, HPA043292, HPA077864 Uncertain Approved Cytosol Not detected epididymis: 0.0 -CTD-2287O16.3 ENSG00000268714 5 116022391-116058928 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected appendix: 0.4 -HSFX2 ENSG00000268738 Heat shock transcription factor family, X-linked 2 X 149592515-149594716 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA051700 Uncertain Tissue enriched 9 testis: 9.3 seminal vesicle: 1.0 -CTD-2583A14.10 ENSG00000268750 19 57819719-57858941 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA056213 Uncertain Mixed duodenum: 5.1 -CTC-429P9.4 ENSG00000268790 19 16577642-16660115 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed endometrium: 1.3 -CTD-2207O23.3 ENSG00000268861 19 7382834-7472477 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA042689, HPA071867 Supported Uncertain Cytosol Tissue enhanced 0 lymph node: 17.4 spleen: 12.1 -CTD-3105H18.16 ENSG00000268870 19 12391949-12441082 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA003150, HPA018683 Uncertain Uncertain Nucleoplasm
Microtubule organizing center Not detected lymph node: 0.6 -CT45A1 CT45-1, CT45.1 ENSG00000268940 Cancer/testis antigen family 45, member A1 X 135713453-135723539 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Tissue enriched 42 testis: 12.4 lung: 0.2 -ERVV-2 ENSG00000268964 Endogenous retrovirus group V, member 2 19 53044738-53051076 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 99 placenta: 13.5 testis: 0.1 -SPANXN2 CT11.7, SPANX-N2 ENSG00000268988 SPANX family, member N2 X 143711955-143721423 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045652 Approved Nucleus
Nucleoli fibrillar center Tissue enriched 7 testis: 2.5 epididymis: 0.3 -FAM231C ENSG00000268991 Family with sequence similarity 231, member C 1 16539066-16539575 Predicted intracellular proteins No evidence No evidence No evidence HPA043267, HPA043292, HPA077864 Uncertain Approved Cytosol Not detected testis: 0.3 -AC003006.7 ENSG00000269026 19 57682045-57753575 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA068553 Approved Nucleus Not detected seminal vesicle: 0.2 -MTRNR2L12 ENSG00000269028 MT-RNR2-like 12 3 96617188-96618236 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Expressed in all heart muscle: 14876.2 -CTD-2521M24.10 ENSG00000269035 19 17436611-17460804 Predicted membrane proteins No evidence No evidence HPA041580, HPA042010 Uncertain Uncertain Nuclear membrane Not detected adipose tissue: 0.0 -CALR3 CRT2, CT93, FLJ25355, MGC26577 ENSG00000269058 Calreticulin 3 19 16479057-16496192 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025749, HPA043355, HPA048460 Supported Tissue enriched 94 testis: 98.4 epididymis: 1.0 -ZNF728 ENSG00000269067 Zinc finger protein 728 19 22975468-23003176 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 5 testis: 18.2 thyroid gland: 3.6 -AC010646.3 ENSG00000269095 19 17235940-17255448 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed epididymis: 1.3 -CT45A3 CT45-3, CT45.3 ENSG00000269096 Cancer/testis antigen family 45, member A3 X 135759846-135768191 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Tissue enriched 15 testis: 20.4 lung: 1.3 -TRABD2B TIKI2 ENSG00000269113 TraB domain containing 2B 1 47760528-47996895 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA045817 Approved Tissue enhanced 0 kidney: 7.7 seminal vesicle: 4.8 -FBXO17 FBG4, Fbx17, FBXO26, FLJ11798, FLJ25205, MGC9379 ENSG00000269190 F-box protein 17 19 38941401-38975910 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed kidney: 14.4 -RP11-722G7.1 ENSG00000269226 X 104063871-104076212 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed ovary: 7.6 -MAGIX FLJ21687, JM10, PDZX ENSG00000269313 MAGI family member, X-linked X 49162564-49168483 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA035302 Uncertain Mixed parathyroid gland: 5.5 -IKBKG FIP-3, FIP3, Fip3p, IKK-gamma, IP1, IP2, NEMO, ZC2HC9 ENSG00000269335 Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma X 154541199-154565046 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000426, CAB010373 Uncertain Validated Cytosol Expressed in all spleen: 37.9 -ZNF587B ENSG00000269343 Zinc finger protein 587B 19 57819741-57846238 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043800, HPA053762, HPA072145 Uncertain Uncertain Nucleus Mixed parathyroid gland: 11.1 -SPIB SPI-B ENSG00000269404 Spi-B transcription factor (Spi-1/PU.1 related) 19 50418938-50431313 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018523 Uncertain Tissue enhanced 0 appendix: 56.0;lymph node: 104.6;tonsil: 95.1 spleen: 40.0 -NXF2 CT39, TAPL-2 ENSG00000269405 Nuclear RNA export factor 2 X 102247161-102326719 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA002079 Uncertain Group enriched 21 epididymis: 18.3;testis: 23.2 fallopian tube: 0.9 -OPN1MW3 ENSG00000269433 Opsin 1 (cone pigments), medium-wave-sensitive 3 X 154257538-154271805 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level Not detected skin: 0.1 -NXF2B bA353J17.1 ENSG00000269437 Nuclear RNA export factor 2B X 102360395-102463274 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA002079 Uncertain Group enriched 6 epididymis: 18.8;testis: 4.9 fallopian tube: 2.1 -DMRTC1 ENSG00000269502 DMRT-like family C1 X 72872025-72943814 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA046874, HPA046992 Uncertain Tissue enhanced 0 cerebral cortex: 2.3 thyroid gland: 1.4 -ERVV-1 ENVV1, FLJ32214, HERV-V1 ENSG00000269526 Endogenous retrovirus group V, member 1 19 53013921-53016122 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 65 placenta: 21.9 prostate: 0.3 -AC003002.6 ENSG00000269533 19 57389884-57419994 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected testis: 0.2 -CTC-360G5.8 ENSG00000269547 19 38915404-38949855 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA052730, HPA056957 Uncertain Mixed ovary: 1.1 -TMEM185A CXorf13, FAM11A, FRAXF ENSG00000269556 Transmembrane protein 185A X 149596556-149631912 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA048295, HPA071744 Uncertain Approved Endoplasmic reticulum Expressed in all ovary: 36.3 -CT45A10 ENSG00000269586 Cancer/testis antigen family 45, member A10 X 135881063-135889086 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Tissue enriched 23 testis: 16.4 cerebral cortex: 0.7 -CTD-2192J16.24 ENSG00000269590 19 12664828-12669397 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA065685 Approved Nuclear membrane
Endoplasmic reticulum Tissue enhanced 0 lymph node: 2.0 duodenum: 1.3 -ZIM2 ZNF656 ENSG00000269699 Zinc finger, imprinted 2 19 56774552-56840729 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA071856 Approved Nuclear speckles
Cytosol Group enriched 6 adrenal gland: 5.8;cerebral cortex: 5.1;ovary: 10.0;placenta: 6.8;testis: 7.8 endometrium: 1.1 -CTD-3214H19.16 ENSG00000269711 19 7678501-7682854 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 bone marrow: 14.1;duodenum: 7.9;lung: 11.8 appendix: 6.7 -NBPF9 AE01 ENSG00000269713 Neuroblastoma breakpoint family, member 9 1 149054027-149103561 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Expressed in all thyroid gland: 22.4 -SLC25A53 MCART6 ENSG00000269743 Solute carrier family 25, member 53 X 104099214-104157027 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA034959 Uncertain Mixed cerebral cortex: 2.6 -SSX4B OTTHUMT00000056510 ENSG00000269791 Synovial sarcoma, X breakpoint 4B X 48402078-48411910 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA045683 Approved Tissue enriched 15 testis: 3.8 fallopian tube: 0.2 -RNF225 ENSG00000269855 Ring finger protein 225 19 58396090-58397079 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 esophagus: 2.0;skin: 1.7 testis: 0.6 -EGLN2 HIFPH1, PHD1 ENSG00000269858 Egl-9 family hypoxia-inducible factor 2 19 40798996-40808433 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA056649 Supported Nucleoplasm Expressed in all testis: 205.0 -AC004754.3 ENSG00000269881 16 249547-269943 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA011651 Uncertain Nucleoplasm
Mitochondria Group enriched 5 duodenum: 14.6;small intestine: 8.1 testis: 2.0 -COMMD3-BMI1 ENSG00000269897 COMMD3-BMI1 readthrough 10 22316388-22329542 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA030471, HPA030472, HPA036584 Uncertain Approved Nucleus
Nucleoli
Nuclear bodies
Cytosol Tissue enhanced 0 testis: 10.1 seminal vesicle: 4.0 -C7orf55-LUC7L2 ENSG00000269955 C7orf55-LUC7L2 readthrough 7 139341360-139422599 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA045663, HPA051631 Approved Approved Nucleus Expressed in all skeletal muscle: 21.0 -MEI4 ENSG00000269964 Meiotic double-stranded break formation protein 4 6 77690658-77926974 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 kidney: 4.5;testis: 4.8;thyroid gland: 3.9 adrenal gland: 0.9 -ZNF559-ZNF177 ENSG00000270011 ZNF559-ZNF177 readthrough 19 9324174-9382617 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA003141 Uncertain Mixed testis: 13.3 -C8orf44-SGK3 ENSG00000270024 C8orf44-SGK3 readthrough 8 66667596-66860472 Predicted intracellular proteins No evidence No evidence HPA027146 Uncertain Not detected cervix: 0.8 -MINOS1-NBL1 ENSG00000270136 MINOS1-NBL1 readthrough 1 19596979-19658056 Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA007394 Uncertain Tissue enhanced 0 duodenum: 16.6;small intestine: 17.5 adipose tissue: 13.7 -LA16c-380H5.3 ENSG00000270168 16 2988256-3002016 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enriched 6 skin: 4.8 lung: 0.7 -NCBP2-AS2 ENSG00000270170 NCBP2 antisense RNA 2 (head to head) 3 196942623-196943540 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all cerebral cortex: 28.7 -BIVM-ERCC5 ENSG00000270181 BIVM-ERCC5 readthrough 13 102807354-102872398 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA045845 Uncertain Mixed thyroid gland: 6.2 -MTRNR2L11 ENSG00000270188 MT-RNR2-like 11 (pseudogene) 1 237943724-237945275 Predicted secreted proteins Evidence at transcript level Evidence at transcript level No evidence Expressed in all skeletal muscle: 113.5 -RP11-514P8.7 ENSG00000270249 7 102541501-102592444 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA046970 Uncertain Uncertain Nucleoplasm Tissue enhanced 0 parathyroid gland: 3.9 epididymis: 1.0 -HIST2H4B H4/o ENSG00000270276 Histone cluster 2, H4b 1 149854045-149861210 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Mixed fallopian tube: 4.6 -RP5-850E9.3 ENSG00000270299 20 646626-675800 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 5.8 testis: 3.3 -AC243756.1 ENSG00000270339 1 146344006-146344790 Predicted intracellular proteins No evidence No evidence HPA058345 Uncertain Not detected spleen: 0.2 -HEATR9 C17orf66, FLJ32830 ENSG00000270379 HEAT repeat containing 9 17 35854946-35868891 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA023129 Uncertain Tissue enriched 34 testis: 9.9 spleen: 0.2 -MTRNR2L13 ENSG00000270394 MT-RNR2-like 13 4 116298876-116300320 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Not detected adrenal gland: 0.8 -PRAMEF5 PRAMEF23, PRAMEF5L ENSG00000270601 PRAME family member 5 1 13254212-13263314 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected epididymis: 0.0 -URGCP-MRPS24 ENSG00000270617 URGCP-MRPS24 readthrough 7 43866558-43906589 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed cervix: 1.3 -NBPF14 DJ328E19.C1.1 ENSG00000270629 Neuroblastoma breakpoint family, member 14 1 148531385-148679751 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046392, HPA046971, HPA058050 Uncertain Approved Vesicles Expressed in all skin: 53.0 -TAF15 hTAFII68, Npl3, RBP56, TAF2N ENSG00000270647 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 17 35713791-35864615 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052059, HPA063647 Supported Validated Nucleoplasm Expressed in all lymph node: 61.9 -MTRNR2L6 ENSG00000270672 MT-RNR2-like 6 7 142666272-142667718 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Expressed in all skeletal muscle: 131.8 -HSPE1-MOB4 ENSG00000270757 HSPE1-MOB4 readthrough 2 197500413-197550726 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA038755, HPA044125, HPA048272 Approved Mixed adrenal gland: 32.9 -GAS2L2 GAR17 ENSG00000270765 Growth arrest-specific 2 like 2 17 35744511-35752878 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA044370 Supported Tissue enriched 11 fallopian tube: 27.8 epididymis: 2.6 -RPS10-NUDT3 ENSG00000270800 RPS10-NUDT3 readthrough 6 34288770-34426048 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA047027, HPA047268, HPA048084, HPA055953 Uncertain Approved Cytosol Mixed cerebral cortex: 35.5 -C17orf50 ENSG00000270806 Chromosome 17 open reading frame 50 17 35760897-35765079 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA043184, HPA063464 Supported Nucleoplasm Tissue enriched 52 testis: 39.2 fallopian tube: 0.7 -HIST2H4A H4/n, H4F2, H4FN, HIST2H4 ENSG00000270882 Histone cluster 2, H4a 1 149832659-149839767 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Mixed fallopian tube: 13.0 -RASL10B RRP17, VTS58635 ENSG00000270885 RAS-like, family 10, member B 17 35731649-35743521 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046842, HPA057092 Approved Approved Vesicles Tissue enhanced 0 adipose tissue: 15.9;seminal vesicle: 20.7 skeletal muscle: 11.1 -GPR75-ASB3 ENSG00000270898 GPR75-ASB3 readthrough 2 53670293-53860160 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA003940 Uncertain Tissue enhanced 0 cerebral cortex: 1.0 spleen: 0.3 -CT45A9 ENSG00000270946 Cancer/testis antigen family 45, member A9 X 135863776-135871812 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Tissue enriched 13 testis: 1.2 epididymis: 0.0 -CTAGE15 CTAGE15P ENSG00000271079 CTAGE family, member 15 7 143571801-143574387 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA000387, HPA000922 Uncertain Tissue enhanced 0 testis: 7.2 thyroid gland: 1.9 -TMEM56-RWDD3 ENSG00000271092 TMEM56-RWDD3 readthrough 1 95117923-95247225 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Mixed thyroid gland: 5.1 -AC240274.1 ENSG00000271254 Unmapped 4612-29626 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Uncertain Approved Vesicles Expressed in all testis: 73.6 -UGT2A2 ENSG00000271271 UDP glucuronosyltransferase 2 family, polypeptide A2 4 69589309-69639642 Enzymes, Predicted membrane proteins Evidence at protein level No evidence Evidence at protein level HPA045108 Uncertain Not detected cervix: 0.2 -SRXN1 C20orf139, dJ850E9.2, Npn3, SRX1, YKL086W ENSG00000271303 Sulfiredoxin 1 20 646615-653370 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all adrenal gland: 44.7 -CTAGE6 CTAGE6P, MGC41943 ENSG00000271321 CTAGE family, member 6 7 143755089-143757696 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA000387, HPA000922 Uncertain Tissue enriched 38 testis: 9.9 skin: 0.2 -NBPF19 ENSG00000271383 Neuroblastoma breakpoint family, member 19 1 149390623-149556361 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA042595, HPA043105, HPA043692, HPA044023, HPA046392, HPA046971, HPA058050 Uncertain Approved Vesicles Expressed in all skin: 74.9 -NBPF10 AG1 ENSG00000271425 Neuroblastoma breakpoint family, member 10 1 146064699-146144942 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Expressed in all skin: 38.4 -MMP28 EPILYSIN, MM28, MMP-25, MMP-28 ENSG00000271447 Matrix metallopeptidase 28 17 35756249-35795707 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 testis: 6.4 adipose tissue: 4.2 -CT45A2 CT45-2, CT45.2 ENSG00000271449 Cancer/testis antigen family 45, member A2 X 135811668-135820012 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Tissue enriched 14 testis: 1.3 adipose tissue: 0.0 -CCL5 D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228 ENSG00000271503 Chemokine (C-C motif) ligand 5 17 35871491-35880793 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 spleen: 81.8 lymph node: 69.9 -PPIAL4E ENSG00000271567 Peptidylprolyl isomerase A (cyclophilin A)-like 4E 1 144372875-144373659 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA058345 Uncertain Not detected skeletal muscle: 0.1 -LIX1L MGC46719 ENSG00000271601 Limb and CNS expressed 1 like 1 145933423-145958001 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA046996, HPA063598 Uncertain Approved Cytosol Expressed in all ovary: 45.7 -MILR1 Allergin-1, C17orf60, MCA-32 ENSG00000271605 Mast cell immunoglobulin-like receptor 1 17 64449037-64468643 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed appendix: 42.9 -RP11-426L16.10 ENSG00000271810 1 112702614-112711433 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 8.4 parathyroid gland: 3.5 -ANKRD34A ANKRD34 ENSG00000272031 Ankyrin repeat domain 34A 1 145959442-145964582 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA029642, HPA029643 Uncertain Validated Cytosol Tissue enriched 5 cerebral cortex: 12.7 parathyroid gland: 2.4 -GTF2H5 bA120J8.2, C6orf175, FLJ30544, TFB5, TFIIH, TTD, TTD-A, TTDA ENSG00000272047 General transcription factor IIH, polypeptide 5 6 158168352-158199344 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed cerebral cortex: 11.2 -FAM231D ENSG00000272058 Family with sequence similarity 231, member D 1 149702328-149705721 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA043267, HPA043292, HPA077864 Uncertain Approved Cytosol Mixed thyroid gland: 9.6 -XXcos-LUCA11.5 ENSG00000272104 3 50350892-50367923 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA042817 Uncertain Mixed small intestine: 7.1 -HIST2H2AA4 H2A/r ENSG00000272196 Histone cluster 2, H2aa4 1 149851061-149851624 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enhanced 0 testis: 89.1 prostate: 36.3 -RP11-215A19.2 ENSG00000272297 4 186426546-186555328 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enriched 13 testis: 53.7 prostate: 4.0 -NUDT3 DIPP ENSG00000272325 Nudix (nucleoside diphosphate linked moiety X)-type motif 3 6 34279679-34392674 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA047027, HPA055953 Uncertain Approved Cytosol Expressed in all cerebral cortex: 77.3 -KMT2B CXXC10, HRX2, KIAA0304, MLL1B, MLL2, MLL4, TRX2, WBP7 ENSG00000272333 Lysine (K)-specific methyltransferase 2B 19 35718019-35738878 Cancer-related genes, Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA006487 Approved Nucleoplasm
Cytosol Expressed in all testis: 28.8 -POM121C ENSG00000272391 POM121 transmembrane nucleoporin C 7 75416787-75486271 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA043809, HPA049817 Approved Approved Nucleoplasm
Nuclear membrane Expressed in all thyroid gland: 27.8 -CD24 CD24A ENSG00000272398 CD24 molecule 6 106969831-106975627 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level CAB078471 Approved Vesicles Tissue enhanced 0 thyroid gland: 2692.6 esophagus: 1407.8 -FAM47E-STBD1 ENSG00000272414 FAM47E-STBD1 readthrough 4 76251721-76311129 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA053331 Approved Uncertain Plasma membrane
Cytosol Expressed in all adipose tissue: 33.0 -CFAP206 C6orf165, dJ382I10.1, FLJ25974 ENSG00000272514 Cilia and flagella associated protein 206 6 87407983-87464465 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA044891, HPA072261 Approved Approved Nucleoplasm
Cell Junctions Group enriched 30 fallopian tube: 35.3;testis: 107.4 thyroid gland: 2.3 -MUSTN1 Mustang ENSG00000272573 Musculoskeletal, embryonic nuclear protein 1 3 52833114-52835219 Predicted intracellular proteins Evidence at protein level Evidence at transcript level No evidence Evidence at protein level Tissue enriched 6 skeletal muscle: 414.2 cervix: 71.1 -ZNF595 FLJ31740 ENSG00000272602 Zinc finger protein 595 4 53285-88211 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Expressed in all placenta: 87.4 -RP11-343C2.12 ENSG00000272617 16 69328644-69334871 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed testis: 30.0 -DOC2B DOC2BL ENSG00000272636 Double C2-like domains, beta 17 142789-181636 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA043168 Uncertain Mixed cerebral cortex: 14.5 -PCDHB16 KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a ENSG00000272674 Protocadherin beta 16 5 141181399-141186399 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA014668 Supported Vesicles
Plasma membrane Mixed parathyroid gland: 10.6 -CTD-2410N18.5 ENSG00000272772 5 134167170-134226071 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 1.3 heart muscle: 0.6 -KRTAP10-7 KAP10.7, KAP18.7, KRTAP18-7 ENSG00000272804 Keratin associated protein 10-7 21 44600597-44612906 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -RP11-302B13.5 ENSG00000272822 12 48903503-48957365 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed cerebral cortex: 2.1 -DCP1A HSA275986, SMAD4IP1, SMIF ENSG00000272886 Decapping mRNA 1A 3 53283428-53347610 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013202 Approved Supported Cytoplasmic bodies Expressed in all endometrium: 19.0 -RBAK-RBAKDN ENSG00000272968 RBAK-RBAKDN readthrough 7 4983718-5073221 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 156 testis: 110.2 cerebral cortex: 0.7 -C2orf15 MGC29762 ENSG00000273045 Chromosome 2 open reading frame 15 2 99141485-99151487 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA042990 Uncertain Mixed thyroid gland: 9.9 -RP4-583P15.14 ENSG00000273047 20 63738270-63740398 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 kidney: 1.2;liver: 2.4;urinary bladder: 1.3 adipose tissue: 1.0 -RP11-834C11.12 ENSG00000273049 12 53985845-54034888 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 1.4 skeletal muscle: 0.8 -GRIN2B GluN2B, NMDAR2B ENSG00000273079 Glutamate receptor, ionotropic, N-methyl D-aspartate 2B 12 13537337-13981957 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA069762 Approved Tissue enriched 25 cerebral cortex: 13.2 adipose tissue: 0.5 -LYPD4 MGC42718 ENSG00000273111 LY6/PLAUR domain containing 4 19 41837074-41844697 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enriched 745 testis: 164.8 bone marrow: 0.2 -NBPF26 ENSG00000273136 Neuroblastoma breakpoint family, member 26 1 120805418-120841481 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Uncertain Approved Vesicles Mixed skin: 45.9 -RP4-583P15.15 ENSG00000273154 20 63708864-63739103 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adrenal gland: 1.2;appendix: 1.1 duodenum: 0.5 -RP11-38C17.1 ENSG00000273155 2 99154998-99195298 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed appendix: 1.7 -CTB-96E2.2 ENSG00000273171 17 28364288-28368012 Predicted intracellular proteins No evidence No evidence Not detected liver: 0.6 -SNURF ENSG00000273173 SNRPN upstream reading frame 15 24954986-24977850 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA065733 Approved Nuclear speckles Expressed in all cerebral cortex: 197.2 -CTC-432M15.3 ENSG00000273217 5 131425891-131796983 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA037982, HPA037983 Uncertain Approved Centrosome
Cytosol Not detected epididymis: 0.0 -SERPINA3 ENSG00000273259 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 14 94592058-94624646 Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA000893, HPA002560 Supported Group enriched 6 cervix, uterine: 377.8;liver: 1692.1 gallbladder: 159.7 -ZBTB8B DKFZp547H154, RP1-27O5.1, ZNF916B ENSG00000273274 Zinc finger and BTB domain containing 8B 1 32465069-32496686 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA027818, HPA028690, HPA055553 Approved Not detected cerebral cortex: 0.6 -RP11-136C24.3 ENSG00000273291 3 42809446-43055871 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 13 testis: 2.1 rectum: 0.1 -AC011841.1 ENSG00000273496 Unmapped 99351-104855 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected skin: 0.4 -TBC1D3K ENSG00000273513 TBC1 domain family, member 3K 17 37924415-37935365 Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA046969, HPA047745, HPA052553 Uncertain Uncertain Vesicles Tissue enhanced 0 testis: 1.8 lymph node: 0.5 -FOXD4L6 ENSG00000273514 Forkhead box D4-like 6 9 41126430-41128463 Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level HPA012836 Uncertain Approved Nucleus Not detected cerebral cortex: 0.3 -HIST1H4K dJ160A22.1, H4/d, H4F2iii, H4FD ENSG00000273542 Histone cluster 1, H4k 6 27831216-27831527 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Not detected appendix: 0.8 -OR4F16 ENSG00000273547 Olfactory receptor, family 4, subfamily F, member 16 1 685716-686654 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA047705 Uncertain Not detected epididymis: 0.0 -AC136616.1 ENSG00000273554 Unmapped 1139577-1147868 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Group enriched 6 skin: 1.6;testis: 6.9 adrenal gland: 0.6 -CWC25 CCDC49, FLJ20291 ENSG00000273559 CWC25 spliceosome-associated protein homolog 17 38800434-38825481 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB014874, HPA062997 Supported Validated Nuclear speckles Mixed bone marrow: 18.8 -SMIM11B ENSG00000273590 Small integral membrane protein 11B 21 7744962-7777853 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051321 Uncertain Approved Focal adhesion sites Expressed in all epididymis: 25.9 -C17orf96 LOC100170841, PRR28 ENSG00000273604 Chromosome 17 open reading frame 96 17 38671703-38675421 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA055190, HPA056555 Uncertain Supported Nucleoplasm
Cytosol
Cytoplasmic bodies Tissue enhanced 0 cerebral cortex: 5.6;testis: 5.0 parathyroid gland: 2.1 -ZNHIT3 TRIP3 ENSG00000273611 Zinc finger, HIT-type containing 3 17 36486629-36499310 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA060019 Approved Mitochondria Expressed in all testis: 42.7 -CT45A7 ENSG00000273696 Cancer/testis antigen family 45, member A7 X 135829247-135837268 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Tissue enriched 6 testis: 1.5 cerebral cortex: 0.2 -HIST1H2BM dJ160A22.3, H2B/e, H2BFE ENSG00000273703 Histone cluster 1, H2bm 6 27815044-27815424 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 bone marrow: 3.3;lymph node: 2.7 tonsil: 1.5 -LHX1 LIM-1, LIM1 ENSG00000273706 LIM homeobox 1 17 36936785-36944612 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB002770 Uncertain Tissue enriched 6 kidney: 1.3 fallopian tube: 0.2 -AL592183.1 ENSG00000273748 Unmapped 54224-83311 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA049380 Approved Expressed in all gallbladder: 147.9 -CYFIP1 KIAA0068, P140SRA-1, SHYC ENSG00000273749 Cytoplasmic FMR1 interacting protein 1 15 22867052-22981063 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA068106 Approved Expressed in all parathyroid gland: 110.1 -CEACAM20 UNQ9366 ENSG00000273777 Carcinoembryonic antigen-related cell adhesion molecule 20 19 44501677-44529788 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Group enriched 24 duodenum: 39.9;prostate: 15.5;small intestine: 43.6 gallbladder: 1.3 -HIST1H2BG H2B.1A, H2B/a, H2BFA ENSG00000273802 Histone cluster 1, H2bg 6 26215159-26216692 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 breast: 17.1;prostate: 10.6 bone marrow: 4.6 -USP27X USP27 ENSG00000273820 Ubiquitin specific peptidase 27, X-linked X 49879948-49882565 Enzymes, Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA077264 Approved Vesicles Tissue enhanced 0 placenta: 19.6 cerebral cortex: 10.4 -TAF9 AD-004, CGI-137, MGC1603, MGC3647, MGC5067, TAF2G, TAFII31, TAFII32, TAFIID32 ENSG00000273841 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 5 69364743-69370013 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028930, HPA053429, HPA058961 Validated Nucleoplasm Expressed in all testis: 144.9 -NOL12 MGC3731, Nop25, RRP17 ENSG00000273899 Nucleolar protein 12 22 37681673-37693478 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003547 Uncertain Approved Nucleus
Nucleoli
Vesicles Expressed in all adrenal gland: 25.2 -GOLGA6L1 ENSG00000273976 Golgin A6 family-like 1 15 23128268-23136822 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA047733 Uncertain Tissue enriched 13 testis: 5.2 bone marrow: 0.4 -HIST1H3G H3/h, H3FH ENSG00000273983 Histone cluster 1, H3g 6 26269405-26271815 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Not detected small intestine: 0.5 -RP11-475E11.9 ENSG00000274068 1 108837660-108963484 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 parathyroid gland: 1.5 cerebral cortex: 0.9 -GATSL2 GATSL1 ENSG00000274070 GATS protein-like 2 7 74964818-75024798 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA057229 Uncertain Tissue enhanced 0 cerebral cortex: 15.0 skeletal muscle: 13.8 -OR4M2 ENSG00000274102 Olfactory receptor, family 4, subfamily M, member 2 15 22080527-22081659 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA058889 Uncertain Tissue enriched 10 testis: 1.2 cerebral cortex: 0.1 -AC133551.1 ENSG00000274175 Unmapped 17234-19833 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Group enriched 30 epididymis: 4.8;testis: 2.6 adrenal gland: 0.1 -NATD1 C17orf103, Gtlf3b, MGC33894 ENSG00000274180 N-acetyltransferase domain containing 1 17 21238870-21253410 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Expressed in all thyroid gland: 16.9 -H2AFB1 ENSG00000274183 H2A histone family, member B1 X 154884972-154885558 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 9 testis: 4.3 skin: 0.4 -ANTXRL ENSG00000274209 Anthrax toxin receptor-like 10 46286345-46330207 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Group enriched 14 breast: 3.1;testis: 15.5 bone marrow: 0.6 -SOCS7 NAP4, NCKAP4 ENSG00000274211 Suppressor of cytokine signaling 7 17 38352228-38405593 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA004475 Approved Approved Cytosol Tissue enhanced 0 testis: 54.3 thyroid gland: 13.1 -TBC1D3H ENSG00000274226 TBC1 domain family, member 3H 17 36377531-36388423 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046969, HPA047745, HPA052553 Uncertain Approved Vesicles Tissue enhanced 0 testis: 2.7;urinary bladder: 1.1 cervix: 0.6 -GGTLC3 ENSG00000274252 Gamma-glutamyltransferase light chain 3 22 18516344-18518161 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA045635, HPA047534 Uncertain Tissue enhanced 0 lung: 1.9;testis: 1.0 small intestine: 0.5 -HIST1H3B H3/l, H3FL ENSG00000274267 Histone cluster 1, H3b 6 26031650-26032060 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Tissue enriched 6 bone marrow: 6.1 lymph node: 0.9 -GAGE13 GAGE12A ENSG00000274274 G antigen 13 X 49331616-49338952 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Tissue enriched 438 testis: 43.8 epididymis: 0.0 -CBSL ENSG00000274276 Cystathionine-beta-synthase like 21 6444869-6468040 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA001223 Supported Approved Nucleoli
Vesicles Tissue enhanced 0 cerebral cortex: 46.0;liver: 27.4 thyroid gland: 22.1 -ADRA2B ADRA2L1, ADRA2RL1, ADRARL1 ENSG00000274286 Adrenoceptor alpha 2B 2 96112875-96116245 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA066029 Approved Mixed epididymis: 5.0 -HIST1H2BE H2B.h, H2B/h, H2BFH ENSG00000274290 Histone cluster 1, H2be 6 26172059-26184655 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed prostate: 2.8 -ZNF658 DKFZp572C163, FLJ32813, MGC35232 ENSG00000274349 Zinc finger protein 658 9 66856426-66932141 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA047730, HPA048668 Uncertain Approved Nucleoplasm Mixed skin: 9.7 -TPTE CT44, PTEN2 ENSG00000274391 Transmembrane phosphatase with tensin homology 21 10521553-10606140 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA049690, HPA068342 Supported Approved Endoplasmic reticulum
Cytosol Tissue enriched 225 testis: 198.9 epididymis: 0.8 -TBC1D3D ENSG00000274419 TBC1 domain family, member 3D 17 38003976-38139051 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046969, HPA047745, HPA052553 Uncertain Uncertain Vesicles Tissue enhanced 0 skin: 4.7;small intestine: 5.6 testis: 3.3 -C8orf89 ENSG00000274443 Chromosome 8 open reading frame 89 8 73241329-73259502 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 8 testis: 13.2 cervix: 1.5 -TBC1D3L ENSG00000274512 TBC1 domain family, member 3L 17 37977972-38068651 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046969, HPA047745, HPA052553 Uncertain Uncertain Vesicles Mixed skin: 41.4 -WBSCR16 ENSG00000274523 Williams-Beuren syndrome chromosome region 16 7 75027122-75074228 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA052184, HPA060643 Approved Approved Nucleus
Cytosol Expressed in all skeletal muscle: 36.4 -RP11-146B14.1 ENSG00000274527 9 6720863-7077263 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 6.5 breast: 2.2 -SEBOX OG9, OG9X ENSG00000274529 SEBOX homeobox 17 28364268-28365244 Predicted intracellular proteins, Transcription factors No evidence No evidence No evidence HPA045689 Uncertain Not detected testis: 0.6 -DGKK ENSG00000274588 Diacylglycerol kinase, kappa X 50365409-50470738 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enriched 7 adrenal gland: 4.6 cerebral cortex: 0.6 -RIMBP3B ENSG00000274600 RIMS binding protein 3B 22 21383374-21389478 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA001183 Supported Uncertain Vesicles
Plasma membrane Tissue enriched 26 testis: 12.1 parathyroid gland: 0.4 -TBC1D3 DKFZp434P2235, PRC17, TBC1D3A ENSG00000274611 TBC1 domain family, member 3 17 38181659-38192541 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046969, HPA047745, HPA052553 Uncertain Uncertain Vesicles Tissue enhanced 0 small intestine: 3.9;testis: 6.2 endometrium: 3.4 -HIST1H4F H4, H4/c, H4FC ENSG00000274618 Histone cluster 1, H4f 6 26240426-26240737 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Not detected bone marrow: 0.8 -HIST1H2BO H2B.2, H2B/n, H2BFN ENSG00000274641 Histone cluster 1, H2bo 6 27893463-27893843 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 bone marrow: 2.1 lymph node: 1.4 -CCL23 Ckb-8, CKb8, MIP-3, MPIF-1, SCYA23 ENSG00000274736 Chemokine (C-C motif) ligand 23 17 36013056-36017968 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA042015 Uncertain Tissue enhanced 0 smooth muscle: 15.2 lung: 11.2 -TCEB3CL2 ENSG00000274744 Transcription elongation factor B polypeptide 3C-like 2 18 46962768-46964408 Predicted intracellular proteins No evidence No evidence No evidence HPA048971, HPA049178, HPA050086 Uncertain Not detected adipose tissue: 0.0 -KRTAP7-1 KAP7.1 ENSG00000274749 Keratin associated protein 7-1 (gene/pseudogene) 21 30829039-30829759 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected skin: 0.1 -HIST1H3E H3.1, H3/d, H3FD ENSG00000274750 Histone cluster 1, H3e 6 26224199-26227473 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Mixed epididymis: 6.6 -PRAMEF27 ENSG00000274764 PRAME family member 27 1 13049476-13056491 Predicted intracellular proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -F8A2 ENSG00000274791 Coagulation factor VIII-associated 2 X 155382115-155383230 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046960 Uncertain Not detected adipose tissue: 0.0 -AC171558.1 ENSG00000274792 Unmapped 386278-387620 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA057442 Uncertain Uncertain Centrosome Tissue enriched 11 testis: 4.3 cerebral cortex: 0.4 -TBC1D3B PRC17, TBC1D3I ENSG00000274808 TBC1 domain family, member 3B 17 36165624-36264527 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046969, HPA047745, HPA052553 Uncertain Uncertain Vesicles Tissue enhanced 0 skin: 6.3 testis: 5.9 -NPHP3-ACAD11 ENSG00000274810 NPHP3-ACAD11 readthrough (NMD candidate) 3 132558142-132722459 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed ovary: 5.1 -AC145212.2 ENSG00000274847 Unmapped 53594-115055 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA053929 Uncertain Uncertain Intermediate filaments Mixed adrenal gland: 10.3 -RP11-214K3.25 ENSG00000274874 12 123973944-124088594 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed cerebral cortex: 1.3 -PANO1 PANO ENSG00000274897 Proapoptotic nucleolar protein 1 11 797511-799190 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed skin: 1.5 -TBC1D3I ENSG00000274933 TBC1 domain family, member 3I 17 36253456-36264553 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level No evidence HPA046969, HPA047745, HPA052553 Uncertain Uncertain Vesicles Tissue enhanced 0 testis: 1.0 skin: 0.3 -RP5-864K19.6 ENSG00000274944 1 38864501-38881617 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA041188, HPA078331 Uncertain Approved Mitochondria
Cytosol Tissue enhanced 0 testis: 10.9 lymph node: 3.7 -HIST1H2AH dJ86C11.1, H2A/S, H2AFALii ENSG00000274997 Histone cluster 1, H2ah 6 27147129-27147515 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB004030, HPA041189 Supported Tissue enhanced 0 bone marrow: 7.4 testis: 2.5 -ZNF280B 5'OY11.1, SUHW2, ZNF279, ZNF632 ENSG00000275004 Zinc finger protein 280B 22 22484421-22509154 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA059519 Uncertain Approved Nucleoplasm Tissue enriched 7 testis: 12.6 cerebral cortex: 1.8 -MLLT6 AF17, FLJ23480 ENSG00000275023 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6 17 38705542-38729803 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA004021 Approved Approved Nucleus Expressed in all parathyroid gland: 35.2 -TP53TG3E ENSG00000275034 TP53 target 3 family member E 16 33303739-33306935 Predicted intracellular proteins No evidence No evidence Not detected placenta: 0.2 -RP11-546B8.6 ENSG00000275038 5 171305981-171308755 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected epididymis: 0.0 -PPP4R3B FLFL2, FLJ31474, KIAA1387, PSY2, SMEK2 ENSG00000275052 Protein phosphatase 4, regulatory subunit 3B 2 55547292-55618880 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001233, CAB017185 Uncertain Supported Nucleoplasm
Nuclear speckles
Centrosome Expressed in all thyroid gland: 57.8 -AC233755.1 ENSG00000275063 Unmapped 41444-41876 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 urinary bladder: 1052.6 tonsil: 673.6 -SYNRG AP1GBP1, MGC104959, SYNG ENSG00000275066 Synergin, gamma 17 37514797-37609496 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023554, HPA023555 Approved Approved Cytosol Expressed in all testis: 20.3 -NUDT18 FLJ22494, MTH3 ENSG00000275074 Nudix (nucleoside diphosphate linked moiety X)-type motif 18 8 22106872-22109419 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028581, HPA030125 Approved Supported Nucleoplasm
Golgi apparatus Mixed epididymis: 16.0 -ZNF2 A1-5, Zfp661, ZNF661 ENSG00000275111 Zinc finger protein 2 2 95165432-95184317 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at transcript level Evidence at protein level HPA041358 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Mixed parathyroid gland: 6.3 -GAGE2E GAGE8 ENSG00000275113 G antigen 2E X 49341192-49345922 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA043232 Approved Uncertain Golgi apparatus
Plasma membrane
Cytosol Group enriched 61 stomach: 15.3;testis: 9.8 small intestine: 0.2 -HIST1H4L H4.k, H4/k, H4FK ENSG00000275126 Histone cluster 1, H4l 6 27873199-27873510 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Not detected bone marrow: 0.3 -CCL16 CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4 ENSG00000275152 Chemokine (C-C motif) ligand 16 17 35976493-35981496 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 73 liver: 60.7 spleen: 0.8 -RP11-385J1.3 ENSG00000275163 3 178419123-178843300 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enriched 6 fallopian tube: 8.7 kidney: 1.5 -LENG9 ENSG00000275183 Leukocyte receptor cluster (LRC) member 9 19 54461796-54463711 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA051671, HPA053556 Approved Approved Nucleoli fibrillar center Mixed duodenum: 5.4 -AC079355.1 ENSG00000275217 7 63762476-63765094 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 206 testis: 30.6 spleen: 0.1 -HIST1H2AK H2A/d, H2AFD ENSG00000275221 Histone cluster 1, H2ak 6 27837947-27838339 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enhanced 0 gallbladder: 1.9 testis: 1.8 -AC171558.2 ENSG00000275249 Unmapped 372322-373405 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA058889 Uncertain Tissue enriched 26 testis: 2.5 adipose tissue: 0.0 -CCL4 Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4 ENSG00000275302 Chemokine (C-C motif) ligand 4 17 36103590-36105621 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB007805 Approved Tissue enhanced 0 spleen: 25.2 lymph node: 17.9 -SGK223 ENSG00000275342 Tyrosine-protein kinase SgK223 8 8317736-8386498 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA012066 Uncertain Approved Nucleoplasm
Centrosome
Cytosol Tissue enhanced 0 thyroid gland: 28.2 small intestine: 12.5 -C7orf77 ENSG00000275356 Chromosome 7 open reading frame 77 7 124777292-124790689 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Not detected lung: 0.5 -HIST1H3I H3.f, H3/f, H3FF ENSG00000275379 Histone cluster 1, H3i 6 27871905-27872315 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Tissue enhanced 0 bone marrow: 1.1 appendix: 0.7 -CCL18 AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18 ENSG00000275385 Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 17 36064280-36072032 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Tissue enhanced 0 adipose tissue: 20.6;lung: 13.1;tonsil: 10.9 lymph node: 6.3 -FCGBP FC(GAMMA)BP ENSG00000275395 Fc fragment of IgG binding protein 19 39863323-39934626 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level HPA003517, HPA003564 Supported Approved Golgi apparatus
Plasma membrane
Cytokinetic bridge Tissue enhanced 0 colon: 194.4 thyroid gland: 109.6 -HNF1B HNF1beta, LFB3, MODY5, TCF2, VHNF1 ENSG00000275410 HNF1 homeobox B 17 37686432-37745247 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002083, CAB068192 Supported Supported Nucleoplasm Tissue enhanced 0 gallbladder: 21.6;kidney: 25.2 lung: 9.6 -CH507-9B2.5 ENSG00000275464 21 5130871-5154734 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA024573 Uncertain Approved Nucleoli
Cytosol Expressed in all cerebral cortex: 16.1 -C17orf98 LOC388381 ENSG00000275489 Chromosome 17 open reading frame 98 17 38835088-38841455 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA051696 Uncertain Tissue enriched 50 testis: 9.6 skin: 0.1 -TCEB3CL HsT828 ENSG00000275553 Transcription elongation factor B polypeptide 3C-like 18 46968695-47029842 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level HPA048971, HPA049178, HPA050086 Uncertain Not detected epididymis: 0.1 -GRIFIN ENSG00000275572 Galectin-related inter-fiber protein 7 2474844-2476894 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected skin: 0.7 -XKR5 ENSG00000275591 XK, Kell blood group complex subunit-related family, member 5 8 6808517-6835644 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cervix, uterine: 1.1 testis: 0.9 -HIST1H4G H4/l, H4FL ENSG00000275663 Histone cluster 1, H4g 6 26246681-26246977 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Not detected small intestine: 0.2 -RP11-697E2.12 ENSG00000275674 15 90266317-90314499 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 duodenum: 1.2 cerebral cortex: 0.8 -RP11-249C24.12 ENSG00000275691 16 56676132-56677763 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 thyroid gland: 1.1 rectum: 0.7 -AATF BFR2, CHE-1, CHE1, DED ENSG00000275700 Apoptosis antagonizing transcription factor 17 36948875-37056871 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA004940 Uncertain Expressed in all lymph node: 20.1 -HIST1H2BH H2B/j, H2BFJ ENSG00000275713 Histone cluster 1, H2bh 6 26251651-26253710 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 duodenum: 3.1 small intestine: 1.2 -HIST1H3A H3/A, H3FA ENSG00000275714 Histone cluster 1, H3a 6 26020490-26020900 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Group enriched 5 bone marrow: 6.7;epididymis: 1.8;testis: 3.7 cervix: 0.8 -CCL15 HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3 ENSG00000275718 Chemokine (C-C motif) ligand 15 17 35996440-36002038 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA058608 Approved Golgi apparatus
Vesicles Tissue enhanced 0 duodenum: 22.1;rectum: 31.0;small intestine: 27.2 colon: 19.3 -LYZL6 LYC1, PRO1485, TKAL754 ENSG00000275722 Lysozyme-like 6 17 35934518-35943699 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA025734, HPA053073 Supported Not detected testis: 0.1 -RP11-449H3.3 ENSG00000275740 5 146203550-146339251 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA035944, HPA036422 Approved Approved Nuclear speckles Tissue enriched 5 testis: 12.3 thyroid gland: 2.4 -HNRNPCL2 HNRNPCP5 ENSG00000275774 Heterogeneous nuclear ribonucleoprotein C-like 2 1 13115496-13116854 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected testis: 0.1 -RIMBP3 KIAA1666, RIMBP3.1, RIMBP3A ENSG00000275793 RIMS binding protein 3 22 18605815-18611919 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA001183 Supported Uncertain Vesicles
Plasma membrane Tissue enriched 38 testis: 45.4 parathyroid gland: 1.2 -ARHGAP23 KIAA1501 ENSG00000275832 Rho GTPase activating protein 23 17 38419280-38512392 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019818, HPA047291 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Mixed cerebral cortex: 42.0 -TUBGCP5 GCP5, KIAA1899 ENSG00000275835 Tubulin, gamma complex associated protein 5 15 22983192-23039673 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039366, HPA040366 Supported Supported Centrosome
Cytosol Expressed in all testis: 24.5 -AC136612.1 ENSG00000275869 Unmapped 933862-936467 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 5 testis: 4.2 epididymis: 0.8 -U2AF1L5 ENSG00000275895 U2 small nuclear RNA auxiliary factor 1-like 5 21 6484623-6499261 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA044833, HPA052083 Supported Uncertain Nucleoplasm Expressed in all tonsil: 103.0 -PRSS2 TRY2 ENSG00000275896 Protease, serine, 2 (trypsin 2) 7 142748662-142774564 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA062452, HPA063471 Supported Approved Endoplasmic reticulum
Vesicles Tissue enriched 53 pancreas: 30691.5 small intestine: 579.8 -TBC1D3F ENSG00000275954 TBC1 domain family, member 3F 17 36428618-36439566 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA046969 Uncertain Uncertain Vesicles Tissue enriched 16 testis: 1.5 adipose tissue: 0.0 -SPATA31A3 DKFZp434B204, FAM75A3 ENSG00000275969 SPATA31 subfamily A, member 3 9 66986304-66992583 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 52 testis: 5.1 adipose tissue: 0.0 -CH507-42P11.8 ENSG00000275993 21 6111134-6123739 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA038211 Uncertain Mixed adrenal gland: 73.6 -AC007325.1 ENSG00000276017 Unmapped 72411-74814 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 87 testis: 16.5 adipose tissue: 0.1 -DUSP14 MKP-L, MKP6 ENSG00000276023 Dual specificity phosphatase 14 17 37489831-37513501 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA019911 Approved Approved Nucleoplasm
Cytosol Tissue enhanced 0 fallopian tube: 5.0 skin: 2.7 -SPATA31A7 FAM75A4, FAM75A7, SPATA31A4 ENSG00000276040 SPATA31 subfamily A, member 7 9 61190003-61196280 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 26 testis: 2.5 adipose tissue: 0.0 -UHRF1 FLJ21925, ICBP90, Np95, RNF106, TDRD22 ENSG00000276043 Ubiquitin-like with PHD and ring finger domains 1 19 4903080-4962154 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049408 Supported Nucleoplasm Tissue enhanced 0 lymph node: 19.0 bone marrow: 17.5 -ORAI1 CRACM1, FLJ14466, TMEM142A ENSG00000276045 ORAI calcium release-activated calcium modulator 1 12 121626550-121642677 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016583, HPA061823 Approved Supported Cytosol Expressed in all parathyroid gland: 48.9 -CCL4L2 ENSG00000276070 Chemokine (C-C motif) ligand 4-like 2 17 36210924-36212878 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 bone marrow: 17.1 gallbladder: 10.5 -CH507-152C13.3 ENSG00000276076 Alpha-crystallin A chain 21 6560714-6564489 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA037737 Approved Nucleoplasm
Cytosol Tissue enriched 13 kidney: 57.1 liver: 4.3 -CCL3L3 MGC12815 ENSG00000276085 Chemokine (C-C motif) ligand 3-like 3 17 36194869-36196758 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 8 bone marrow: 7.4;gallbladder: 1.5 lymph node: 0.5 -OR13C2 ENSG00000276119 Olfactory receptor, family 13, subfamily C, member 2 9 104604671-104605627 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected cerebral cortex: 0.1 -HIST1H4I H4/m, H4FM ENSG00000276180 Histone cluster 1, H4i 6 27138588-27139881 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Mixed prostate: 12.1 -ANKRD20A3 ENSG00000276203 Ankyrin repeat domain 20 family, member A3 9 66106815-66153135 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA043239, HPA047112, HPA047167, HPA047766, HPA051753 Uncertain Not detected testis: 0.4 -PIK3R6 C17orf38, FLJ34500, HsT41028, p87PIKAP ENSG00000276231 Phosphoinositide-3-kinase, regulatory subunit 6 17 8802723-8867677 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA023077 Approved Mixed spleen: 4.1 -TADA2A ADA2, ADA2A, hADA2, TADA2L ENSG00000276234 Transcriptional adaptor 2A 17 37406874-37479730 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA076497 Approved Nuclear speckles Mixed testis: 13.8 -AC011043.1 ENSG00000276256 Uncharacterized protein LOC389831 Unmapped 42939-49164 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed kidney: 68.6 -CH507-396I9.6 ENSG00000276289 21 7816675-7829926 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 fallopian tube: 9.0;heart muscle: 4.0 kidney: 2.9 -PIP4K2B PIP5K2B, PIP5KIIB, PIP5KIIbeta ENSG00000276293 Phosphatidylinositol-5-phosphate 4-kinase, type II, beta 17 38765689-38800126 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047875, HPA062220 Approved Supported Nucleoplasm Expressed in all cerebral cortex: 51.8 -RP5-874C20.8 ENSG00000276302 6 28267121-28281580 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed cerebral cortex: 1.7 -AC004556.1 ENSG00000276345 Unmapped 2585-11802 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA050406 Uncertain Supported Nucleoli fibrillar center
Mitochondria Mixed breast: 24.6 -HIST1H2AJ H2A/E, H2AFE ENSG00000276368 Histone cluster 1, H2aj 6 27814354-27814740 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enhanced 0 bone marrow: 6.5 lymph node: 1.4 -CCL14 CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2 ENSG00000276409 Chemokine (C-C motif) ligand 14 17 35983291-35987004 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB004423, HPA030268 Uncertain Tissue enhanced 0 spleen: 276.2 adipose tissue: 123.1 -HIST1H2BB H2B/f, H2BFF ENSG00000276410 Histone cluster 1, H2bb 6 26043227-26123904 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Group enriched 6 bone marrow: 1.0;testis: 3.2 lymph node: 0.3 -FAM25C bA164N7.4 ENSG00000276430 Family with sequence similarity 25, member C 10 47995355-47999791 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence HPA044808 Uncertain Group enriched 14 breast: 5.3;esophagus: 4.0;skin: 9.1;small intestine: 4.4;tonsil: 2.2 skeletal muscle: 0.3 -PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 Protocadherin gamma subfamily B, 5 5 141397987-141512979 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA008755 Uncertain Tissue enhanced 0 parathyroid gland: 19.4 thyroid gland: 7.5 -SPATA31A5 FAM75A5 ENSG00000276581 SPATA31 subfamily A, member 5 9 60914374-60920650 Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.7 -RAB7B MGC16212, MGC9726 ENSG00000276600 RAB7B, member RAS oncogene family 1 205976740-206003461 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 skin: 60.0 gallbladder: 23.0 -CH507-9B2.4 ENSG00000276612 21 5116343-5133805 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected adrenal gland: 0.9 -DACH1 DACH ENSG00000276644 Dachshund family transcription factor 1 13 71437966-71867192 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA012672 Approved Supported Nucleoplasm
Vesicles Mixed cervix: 15.0 -PADI6 ENSG00000276747 Peptidyl arginine deiminase, type VI 1 17372196-17401699 Enzymes, Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Not detected adipose tissue: 0.0 -AC136352.4 ENSG00000276760 Unmapped 136160-167571 Predicted intracellular proteins No evidence No evidence HPA042822 Uncertain Not detected epididymis: 0.0 -HIST1H2AL dJ193B12.9, H2A/i, H2AFI ENSG00000276903 Histone cluster 1, H2al 6 27865355-27865747 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enriched 7 bone marrow: 5.2 parathyroid gland: 0.7 -RP4-608O15.3 ENSG00000276911 Complement factor H-related protein 2 1 196819745-196959210 Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA038915, HPA040726, HPA049813 Supported Tissue enriched 530 liver: 201.9 kidney: 0.3 -HIST1H4E H4/j, H4FJ ENSG00000276966 Histone cluster 1, H4e 6 26204552-26206038 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Mixed prostate: 2.0 -HNRNPCL3 ENSG00000277058 Heterogeneous nuclear ribonucleoprotein C-like 3 1 13060869-13062229 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected adipose tissue: 0.0 -HIST1H2AE H2A.1, H2A/a, H2AFA ENSG00000277075 Histone cluster 1, H2ae 6 26216975-26217483 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB012242, HPA041189 Supported Supported Nucleoplasm Tissue enhanced 0 breast: 53.0 prostate: 20.0 -CH507-9B2.1 ENSG00000277117 21 5022493-5040666 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Mixed cerebral cortex: 11.2 -TYW1B LINC00069, MGC87315, NCRNA00069, RSAFD2 ENSG00000277149 TRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 7 72558744-72828198 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA013568, HPA014118, HPA043136, HPA047029, HPA047052, HPA052097 Approved Approved Nucleus
Nucleoli Mixed ovary: 6.7 -F8A3 ENSG00000277150 Coagulation factor VIII-associated 3 X 155456914-155458672 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046960 Uncertain Tissue enhanced 0 parathyroid gland: 32.3 cerebral cortex: 10.6 -HIST1H4D H4/b, H4FB ENSG00000277157 Histone cluster 1, H4d 6 26188765-26189076 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Mixed fallopian tube: 1.7 -PIGW FLJ37433, Gwt1 ENSG00000277161 Phosphatidylinositol glycan anchor biosynthesis, class W 17 36535020-36539310 Disease related genes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA023499 Approved Plasma membrane Mixed appendix: 5.3 -AC007325.2 ENSG00000277196 Unmapped 138082-161852 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA020361 Uncertain Tissue enhanced 0 skin: 38.5;small intestine: 37.8 duodenum: 29.8 -F8A1 DXS522E, F8A ENSG00000277203 Coagulation factor VIII-associated 1 X 154886349-154888061 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046960 Uncertain Expressed in all thyroid gland: 30.0 -HIST1H2BF H2B/g, H2BFG ENSG00000277224 Histone cluster 1, H2bf 6 26199520-26200715 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 esophagus: 3.5;prostate: 2.3 breast: 2.1 -PCGF2 MEL-18, RNF110, ZNF144 ENSG00000277258 Polycomb group ring finger 2 17 38733897-38749817 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA047732, HPA063531 Uncertain Supported Nucleus Mixed parathyroid gland: 18.6 -C10orf142 ENSG00000277288 Chromosome 10 open reading frame 142 10 44292569-44294649 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed testis: 2.8 -GOLGA6L6 FLJ36131 ENSG00000277322 Golgin A6 family-like 6 15 20531856-20541800 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA047733 Uncertain Tissue enriched 42 testis: 4.2 epididymis: 0.0 -SRCIN1 KIAA1684, p140Cap, SNIP ENSG00000277363 SRC kinase signaling inhibitor 1 17 38530016-38605930 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA009701, HPA063795 Approved Approved Cell Junctions Tissue enhanced 0 cerebral cortex: 22.2 skin: 4.7 -GPR179 CSNB1E, GPR158L1 ENSG00000277399 G protein-coupled receptor 179 17 38325530-38343847 Predicted membrane proteins No evidence No evidence HPA017885 Uncertain Not detected epididymis: 0.1 -AC145212.4 ENSG00000277400 MaFF-interacting protein Unmapped 53590-115018 Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Mixed ovary: 8.0 -MARCKS 80K-L, MACS, PKCSL ENSG00000277443 Myristoylated alanine-rich protein kinase C substrate 6 113857362-113863471 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022062, HPA051913, HPA054820 Uncertain Approved Nucleoli
Plasma membrane
Cytosol Expressed in all cerebral cortex: 219.4 -ZNF670 MGC12466 ENSG00000277462 Zinc finger protein 670 1 247036784-247078755 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003142 Uncertain Approved Nucleus
Cytosol Mixed testis: 6.1 -AC213203.1 ENSG00000277475 Unmapped 31698-32528 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 32.2 fallopian tube: 7.4 -PKD1L3 ENSG00000277481 Polycystic kidney disease 1-like 3 16 71929538-71999978 Predicted membrane proteins, Transporters Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected testis: 0.8 -GPIHBP1 GPI-HBP1, LOC338328 ENSG00000277494 Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 8 143213193-143217170 Disease related genes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA066302 Supported Group enriched 6 adipose tissue: 94.1;lung: 33.1 skeletal muscle: 10.5 -RP13-347D8.7 ENSG00000277535 X 119073226-119076373 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 5 testis: 7.6 epididymis: 1.4 -OR13C5 ENSG00000277556 Olfactory receptor, family 13, subfamily C, member 5 9 104598457-104599413 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level Not detected seminal vesicle: 0.1 -NEFL CMT1F, CMT2E, NF68, NFL, PPP1R110 ENSG00000277586 Neurofilament, light polypeptide 8 24950955-24957110 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014850, HPA015021 Supported Supported Approved Nuclear speckles
Intermediate filaments Tissue enriched 10 cerebral cortex: 282.9 adrenal gland: 27.5 -BX072566.1 ENSG00000277630 Uncharacterized protein LOC100288966 Unmapped 108007-139659 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042822 Uncertain Tissue enriched 74 testis: 7.3 epididymis: 0.0 -CCL3 G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3 ENSG00000277632 Chemokine (C-C motif) ligand 3 17 36088256-36090169 Cancer-related genes, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 bone marrow: 50.3 cerebral cortex: 12.4 -AC136352.5 ENSG00000277666 Unmapped 100123-101141 Predicted secreted proteins Evidence at protein level Evidence at protein level HPA003342 Uncertain Not detected epididymis: 0.0 -AC009133.22 ENSG00000277669 16 29663279-29695144 Predicted secreted proteins Evidence at protein level Evidence at protein level HPA011887 Uncertain Tissue enhanced 0 colon: 2.7;duodenum: 1.9;spleen: 1.0 lung: 0.4 -RP4-635E18.9 ENSG00000277726 1 11012662-11030528 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed lung: 3.0 -FP325317.1 ENSG00000277737 9 43109628-43127172 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enriched 8 adipose tissue: 38.3 heart muscle: 4.7 -H2AFB3 H2AFB ENSG00000277745 H2A histone family, member B3 X 155459415-155460005 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 55 testis: 18.5 spleen: 0.3 -ABC7-42404400C24.1 ENSG00000277758 10 47750864-47763592 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA036971, HPA036972, HPA064559 Approved Approved Golgi apparatus Tissue enhanced 0 cerebral cortex: 13.8;lung: 19.5 skin: 5.7 -AC136616.2 ENSG00000277761 Unmapped 1167457-1257196 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed colon: 73.9 -HIST1H3F H3/i, H3FI ENSG00000277775 Histone cluster 1, H3f 6 26250195-26250605 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570, CAB070190 Supported Tissue enhanced 0 bone marrow: 1.4 lymph node: 0.7 -PSMB3 HC10-II, MGC4147 ENSG00000277791 Proteasome subunit beta 3 17 38752736-38764231 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042775, HPA048147 Supported Expressed in all epididymis: 82.2 -AC141272.1 ENSG00000277836 Unmapped 1270984-1271271 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 tonsil: 110.9 urinary bladder: 95.0 -AC233755.2 ENSG00000277856 Unmapped 26241-26534 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 tonsil: 192.2 colon: 96.8 -H2AFB2 ENSG00000277858 H2A histone family, member B2 X 155380787-155381134 Predicted intracellular proteins Evidence at transcript level No evidence Evidence at transcript level Not detected duodenum: 0.6 -GOLGA6L22 ENSG00000277865 Golgin A6 family-like 22 15 22458903-22469230 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA047733 Uncertain Tissue enriched 18 testis: 5.4 cerebral cortex: 0.2 -SRD5A2 ENSG00000277893 Steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 2 31522480-31581067 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Group enriched 11 epididymis: 27.4;fallopian tube: 31.2;liver: 30.6;prostate: 25.3;seminal vesicle: 24.2 testis: 2.4 -OR52E5 ENSG00000277932 Olfactory receptor, family 52, subfamily E, member 5 11 5900777-5902090 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected testis: 0.1 -CISD3 Miner2 ENSG00000277972 CDGSH iron sulfur domain 3 17 38730235-38735044 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA053436, HPA054400 Approved Mixed thyroid gland: 8.7 -RDM1 MGC33977, RAD52B ENSG00000278023 RAD52 motif containing 1 17 35918066-35930773 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA024794 Supported Nucleoli
Cytosol Tissue enriched 8 testis: 9.5 lymph node: 1.2 -DDX52 ROK1 ENSG00000278053 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 17 37609739-37643464 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA056173 Uncertain Supported Nucleus
Nucleoli Mixed epididymis: 5.2 -TEX28 CXorf2, fTEX ENSG00000278057 Testis expressed 28 X 154271265-154295853 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Tissue enriched 33 testis: 6.2 skin: 0.1 -CT45A8 ENSG00000278085 Cancer/testis antigen family 45, member A8 X 135846499-135854538 Predicted intracellular proteins Evidence at protein level Evidence at protein level No evidence HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Tissue enriched 12 testis: 1.2 adipose tissue: 0.0 -ZNF8 HF.18, Zfp128 ENSG00000278129 Zinc finger protein 8 19 58278951-58302805 Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA034797, HPA034798 Uncertain Approved Nucleoplasm
Nuclear bodies Mixed parathyroid gland: 4.7 -PIK3R3 ENSG00000278139 Phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 1 46043661-46176488 Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level Evidence at transcript level HPA005751 Uncertain Tissue enriched 30 testis: 41.0 gallbladder: 1.3 -SSTR3 ENSG00000278195 Somatostatin receptor 3 22 37204238-37212322 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022647 Approved Tissue enhanced 0 testis: 10.9 cerebral cortex: 3.9 -AC011043.2 ENSG00000278198 Unmapped 173872-179372 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected skin: 0.4 -PRICKLE4 C6orf49, DKFZp761H221, OEBT ENSG00000278224 Prickle homolog 4 6 41783474-41787129 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA031240 Uncertain Mitotic spindle
Microtubule organizing center Mixed spleen: 2.6 -MYO19 FLJ22865, MYOHD1 ENSG00000278259 Myosin XIX 17 36495633-36543435 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021415, HPA059715 Approved Validated Cytosol Expressed in all skin: 14.5 -HIST1H3C H3.1, H3/c, H3FC ENSG00000278272 Histone cluster 1, H3c 6 26045411-26045821 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Tissue enhanced 0 bone marrow: 3.3;testis: 1.7 lymph node: 0.9 -CT45A6 CT45-6, CT45.6 ENSG00000278289 Cancer/testis antigen family 45, member A6 X 135794706-135802656 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Not detected testis: 0.6 -TBC1D3C MGC44903 ENSG00000278299 TBC1 domain family, member 3C 17 37978470-38068592 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046969, HPA047745, HPA052553 Approved Uncertain Vesicles Tissue enhanced 0 testis: 4.2 skin: 3.0 -GGNBP2 DIF-3, DIF3, FLJ21230, FLJ22561, LZK1, ZFP403, ZNF403 ENSG00000278311 Gametogenetin binding protein 2 17 36544888-36589848 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA018914, HPA073392 Approved Approved Endoplasmic reticulum Expressed in all testis: 55.4 -ZNF229 ENSG00000278318 Zinc finger protein 229 19 44417519-44448578 Predicted intracellular proteins, Transcription factors Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA001494 Uncertain Approved Vesicles
Plasma membrane Tissue enhanced 0 parathyroid gland: 6.5 thyroid gland: 3.1 -AL354822.1 ENSG00000278384 Unmapped 51867-54893 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed skin: 3.4 -HIST1H2AB H2A/m, H2AFM ENSG00000278463 Histone cluster 1, H2ab 6 26033176-26033568 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Tissue enhanced 0 bone marrow: 1.6 testis: 0.6 -RP11-457D20.2 ENSG00000278499 Putative UPF0607 protein ENSP00000381418 16 60358455-60359480 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 17 testis: 4.4 skeletal muscle: 0.2 -C17orf78 FLJ39647 ENSG00000278505 Chromosome 17 open reading frame 78 17 37375986-37392708 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Group enriched 75 duodenum: 101.8;small intestine: 51.9 testis: 1.0 -POTEB3 ENSG00000278522 POTE ankyrin domain family, member B3 15 21408243-21440451 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA042822 Uncertain Tissue enriched 22 testis: 2.1 adipose tissue: 0.0 -DHRS11 MGC4172, SDR24C1 ENSG00000278535 Dehydrogenase/reductase (SDR family) member 11 17 36591798-36600806 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041226, HPA048236, HPA053623 Supported Approved Golgi apparatus
Cytosol Group enriched 8 colon: 45.4;duodenum: 153.7;rectum: 47.9;small intestine: 136.4 testis: 11.8 -ACACA ACAC, ACC, ACC1 ENSG00000278540 Acetyl-CoA carboxylase alpha 17 37084988-37406818 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB013715, HPA036650, HPA063018 Approved Supported Nucleoli fibrillar center
Actin filaments
Cytosol Mixed breast: 28.4 -TMEM191B ENSG00000278558 Transmembrane protein 191B 22 18527802-18530573 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 18 testis: 27.7 spleen: 1.5 -OR4F29 ENSG00000278566 Olfactory receptor, family 4, subfamily F, member 29 1 450740-451678 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level No evidence Evidence at transcript level HPA047705 Uncertain Not detected adipose tissue: 0.0 -NR2E3 PNR, rd7, RP37 ENSG00000278570 Nuclear receptor subfamily 2, group E, member 3 15 71792638-71818259 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level No evidence Evidence at protein level Evidence at protein level Not detected cervix: 0.7 -HIST1H2BI H2B/k, H2BFK ENSG00000278588 Histone cluster 1, H2bi 6 26272976-26273356 Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Tissue enhanced 0 bone marrow: 1.9;lymph node: 1.7 testis: 0.7 -TBC1D3E ENSG00000278599 TBC1 domain family, member 3E 17 38005561-38138862 Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA046969, HPA047745, HPA052553 Uncertain Uncertain Vesicles Tissue enhanced 0 bone marrow: 1.8;gallbladder: 2.7;testis: 3.8 lymph node: 0.9 -C11orf98 C11orf48 ENSG00000278615 Chromosome 11 open reading frame 98 11 62662816-62665217 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Expressed in all lymph node: 81.7 -MRM1 FLJ22578 ENSG00000278619 Mitochondrial rRNA methyltransferase 1 17 36601572-36608971 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021598 Supported Validated Mitochondria Mixed adrenal gland: 5.0 -AC023491.2 ENSG00000278633 Unmapped 10598-13001 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 536 testis: 67.5 parathyroid gland: 0.1 -HIST1H4A H4FA ENSG00000278637 Histone cluster 1, H4a 6 26021679-26021990 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB021887, HPA042201 Supported Mixed appendix: 1.9 -RP1-321E8.5 ENSG00000278646 X 120877496-120878924 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042483 Approved Tissue enriched 8 testis: 3.3 adrenal gland: 0.4 -GOLGA6L10 GOLGA6L18 ENSG00000278662 Golgin A6 family-like 10 15 82339998-82349475 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enriched 7 testis: 9.3 skin: 1.2 -RP11-49K24.9 ENSG00000278674 18 47022287-47023927 Predicted intracellular proteins No evidence No evidence HPA048971, HPA049178, HPA050086 Uncertain Not detected adipose tissue: 0.0 -HIST1H2AM H2A.1, H2A/n, H2AFN ENSG00000278677 Histone cluster 1, H2am 6 27892757-27893149 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA041189 Supported Mixed lymph node: 2.7 -IQCA1L IQCA1P1, TCAG_9762 ENSG00000278685 IQ motif containing with AAA domain 1 like 7 151190873-151205496 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 41 testis: 4.0 epididymis: 0.0 -BX004987.4 ENSG00000278704 Unmapped 56140-58376 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed placenta: 4.1 -HIST1H4B H4/I, H4FI ENSG00000278705 Histone cluster 1, H4b 6 26026815-26027252 Disease related genes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042201 Supported Tissue enhanced 0 bone marrow: 1.3 lymph node: 0.8 -AC136616.3 ENSG00000278782 Unmapped 1157687-1240349 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cervix, uterine: 8.6;tonsil: 6.5 small intestine: 5.5 -AC007325.4 ENSG00000278817 Unmapped 131494-137392 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 36.9;skeletal muscle: 44.0 heart muscle: 33.2 -HIST1H3H H3/k, H3F1K, H3FK ENSG00000278828 Histone cluster 1, H3h 6 27810064-27811300 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA042570 Supported Mixed rectum: 2.9 -MRPL45 MGC11321 ENSG00000278845 Mitochondrial ribosomal protein L45 17 38297023-38323218 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA023373, HPA023385 Supported Validated Mitochondria Mixed endometrium: 10.2 -TP53TG3F ENSG00000278848 TP53 target 3 family member F 16 33459045-33462249 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Group enriched 9 epididymis: 4.8;testis: 2.7 placenta: 0.4 -AL109927.1 ENSG00000278868 1 27850574-27850744 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adipose tissue: 3.4;skeletal muscle: 1.8 spleen: 0.8 -FP325331.1 ENSG00000278881 Uncharacterized protein UNQ6126/PRO20091 22 47115838-47117217 Predicted secreted proteins Evidence at transcript level No evidence Evidence at transcript level HPA003644 Approved Nucleus
Cytosol Not detected cervix: 0.1 -AC253572.1 ENSG00000278882 1 120723923-120793877 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA046392 Uncertain Mixed skin: 5.1 -AL591806.1 ENSG00000278883 1 161065865-161066153 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed bone marrow: 15.6 -AC090154.1 ENSG00000278888 8 66674499-66675916 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 7.6 gallbladder: 3.7 -AL358852.1 ENSG00000278899 6 149717621-149718888 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed epididymis: 2.0 -AP006285.2 ENSG00000278919 11 1580492-1585989 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected parathyroid gland: 0.6 -AP005242.1 ENSG00000278923 18 15057125-15066579 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Group enriched 12 esophagus: 4.8;prostate: 1.8 smooth muscle: 0.2 -AC104981.1 ENSG00000278938 17 77777090-77777464 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 parathyroid gland: 3.3;testis: 3.6 esophagus: 2.0 -AC242988.1 ENSG00000278939 1 150302770-150303291 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed breast: 12.8 -AC007557.5 ENSG00000278951 2 216863059-216865281 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 11 testis: 15.8 smooth muscle: 1.4 -AL136097.1 ENSG00000279007 9 92227001-92227375 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Expressed in all testis: 45.1 -AC007906.1 ENSG00000279018 16 53207941-53226385 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Mixed parathyroid gland: 2.1 -AC123512.1 ENSG00000279037 12 91986626-91993403 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 lymph node: 9.8 urinary bladder: 5.7 -AL445183.1 ENSG00000279054 1 53053624-53054949 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adipose tissue: 3.2;thyroid gland: 4.5 rectum: 2.2 -CTGLF11P bA145E20.1 ENSG00000279058 Centaurin, gamma-like family, member 11 pseudogene 10 46337224-46358714 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042490 Uncertain Tissue enriched 7 testis: 5.5 prostate: 0.7 -CH17-140K24.5 ENSG00000279068 5 141182409-141188582 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed endometrium: 1.6 -AL356585.2 ENSG00000279081 13 18206570-18207469 Predicted intracellular proteins No evidence No evidence HPA049250 Uncertain Uncertain Nucleoli
Cytosol Not detected adipose tissue: 0.0 -AC022405.1 ENSG00000279084 15 40683694-40684068 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 testis: 1.4;thyroid gland: 1.6 skin: 0.8 -AL356289.1 ENSG00000279096 1 48102068-48104707 Predicted secreted proteins No evidence No evidence Not detected bone marrow: 0.1 -AC008641.1 ENSG00000279109 5 151016918-151017411 Predicted secreted proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC006386.1 ENSG00000279115 Y 25307702-25308107 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA053169 Uncertain Not detected spleen: 0.7 -AC006449.2 ENSG00000279119 17 38727833-38728198 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA023912, HPA074896 Uncertain Approved Vesicles Expressed in all epididymis: 41.4 -AC008810.1 ENSG00000279126 5 40801222-40801596 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Expressed in all skin: 37.7 -AC069063.1 ENSG00000279131 3 115113420-115114210 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adrenal gland: 3.1 thyroid gland: 2.0 -FAM231C ENSG00000279132 Family with sequence similarity 231, member C 1 16733951-16734461 Predicted intracellular proteins No evidence No evidence No evidence HPA043267, HPA043292, HPA077864 Uncertain Approved Cytosol Not detected adipose tissue: 0.0 -AC129492.1 ENSG00000279152 17 8188933-8189688 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed spleen: 1.6 -AC105052.2 ENSG00000279168 7 102672879-102678856 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 parathyroid gland: 11.0 placenta: 2.8 -AC010412.1 ENSG00000279183 19 40647563-40647937 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 testis: 1.4;thyroid gland: 1.6 skin: 0.8 -AL008723.1 ENSG00000279219 22 32191094-32191452 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 5 cerebral cortex: 11.7 prostate: 2.3 -AC019206.1 ENSG00000279229 2 69902350-69902709 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 lymph node: 9.4 cerebral cortex: 7.1 -AL158839.1 ENSG00000279230 1 70363780-70366135 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC008522.1 ENSG00000279232 5 98792863-98795766 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed stomach: 8.9 -AL138706.2 ENSG00000279238 13 37020528-37020772 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed epididymis: 36.3 -AL645728.1 ENSG00000279244 1 1579756-1580046 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed skin: 7.5 -C17orf100 LOC388327 ENSG00000279257 Chromosome 17 open reading frame 100 17 6651914-6652270 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046824 Uncertain Uncertain Nucleus
Cytokinetic bridge
Cytosol Mixed skin: 13.0 -AL360294.1 ENSG00000279261 1 234757621-234760056 Predicted intracellular proteins No evidence No evidence Not detected bone marrow: 0.1 -AC012005.3 ENSG00000279274 Y 24362031-24362436 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA053169 Uncertain Not detected spleen: 0.7 -AL354828.1 ENSG00000279282 13 22663953-22679652 Predicted membrane proteins No evidence No evidence Not detected epididymis: 0.6 -AC012005.4 ENSG00000279287 Y 24196425-24206144 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.1 -AC006994.3 ENSG00000279317 2 210232692-210233976 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 parathyroid gland: 2.3 kidney: 0.6 -AC009977.1 ENSG00000279335 Y 19576009-19576182 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed placenta: 6.1 -AP000866.1 ENSG00000279342 11 124789244-124790069 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Mixed endometrium: 3.2 -AC104389.1 ENSG00000279346 11 5253367-5254782 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 39 placenta: 11.1 cerebral cortex: 0.2 -AC092718.1 ENSG00000279362 16 81170740-81181213 Predicted intracellular proteins No evidence No evidence Not detected ovary: 0.4 -AL162426.1 ENSG00000279363 9 127742855-127743407 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AL596220.1 ENSG00000279374 1 186394991-186396776 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Mixed testis: 6.4 -AC069063.2 ENSG00000279380 3 115120172-115121489 Predicted intracellular proteins No evidence No evidence Not detected skin: 0.4 -AC021106.1 ENSG00000279386 4 37866561-37867091 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed skin: 5.6 -RP11-294C11.3 ENSG00000279408 15 21651844-21653039 Predicted membrane proteins Evidence at transcript level Evidence at transcript level HPA057442 Uncertain Uncertain Centrosome Tissue enriched 17 testis: 14.6 cerebral cortex: 0.8 -AC064829.1 ENSG00000279435 Y 8549671-8748740 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 2.1 testis: 0.7 -AC006026.2 ENSG00000279448 7 23638162-23638536 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Not detected adrenal gland: 0.9 -FO538757.2 ENSG00000279457 1 184923-200322 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA002689 Uncertain Approved Vesicles Expressed in all skin: 30.5 -AC005480.1 ENSG00000279461 14 74003369-74003777 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA053169 Uncertain Not detected skin: 0.6 -AC008759.1 ENSG00000279471 19 9615561-9616905 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed bone marrow: 5.9 -AC009065.4 ENSG00000279473 16 2253737-2262342 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA043155 Uncertain Tissue enhanced 0 colon: 1.6 appendix: 0.5 -AC090498.1 ENSG00000279483 7 137513832-137514238 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA053169 Uncertain Expressed in all ovary: 12.8 -AC234582.1 ENSG00000279487 1 155190050-155191339 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 7 stomach: 2991.1 lung: 403.1 -CH507-9B2.2 ENSG00000279493 21 5011799-5017145 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 kidney: 1.8;liver: 3.1 lymph node: 0.5 -AL589743.1 ENSG00000279508 14 19300177-19302924 Predicted secreted proteins Evidence at transcript level Evidence at transcript level HPA059705 Approved Cytosol Tissue enhanced 0 prostate: 9.5 adipose tissue: 6.4 -AC243945.1 ENSG00000279510 14 22638099-22638473 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Not detected spleen: 0.3 -AC109344.1 ENSG00000279515 2 109344229-109344918 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC108925.1 ENSG00000279524 8 127630283-127630657 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enriched 29 epididymis: 15.0 spleen: 0.5 -AC092881.1 ENSG00000279530 12 70321677-70324274 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 bone marrow: 2.2 lymph node: 0.6 -AC009022.1 ENSG00000279533 16 70052395-70052769 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 smooth muscle: 7.9 parathyroid gland: 7.6 -AC004953.1 ENSG00000279538 7 101635218-101638685 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed skin: 3.0 -AL645922.1 ENSG00000279546 6 32006168-32007104 Predicted intracellular proteins No evidence No evidence Not detected kidney: 0.5 -AC009491.1 ENSG00000279547 Y 8710885-8745985 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.1 -OR4X2 ENSG00000279556 Olfactory receptor, family 4, subfamily X, member 2 (gene/pseudogene) 11 48245104-48246015 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level No evidence Evidence at transcript level Evidence at protein level HPA060249 Uncertain Not detected adipose tissue: 0.0 -AC007326.1 ENSG00000279560 22 18945123-18946971 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Expressed in all epididymis: 108.5 -AP000769.1 ENSG00000279576 Metastasis-associated lung adenocarcinoma transcript 1 11 65502034-65503622 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Expressed in all thyroid gland: 482.6 -AC087762.1 ENSG00000279588 15 100783470-100785235 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected kidney: 0.2 -RP5-1042K10.14 ENSG00000279624 22 40364958-40404362 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cervix, uterine: 1.1;epididymis: 1.1;skin: 1.6 rectum: 0.5 -AC008074.1 ENSG00000279644 2 64552771-64592133 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 2.2 skin: 1.3 -AC016577.1 ENSG00000279646 5 156658587-156660435 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed epididymis: 33.6 -AL135745.1 ENSG00000279654 14 64894339-64894713 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Expressed in all skin: 37.7 -AC009491.2 ENSG00000279664 Y 8695281-8743495 Predicted secreted proteins No evidence No evidence Not detected testis: 0.5 -AC004853.1 ENSG00000279723 7 143959971-143960924 Predicted membrane proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC124312.1 ENSG00000279735 15 25091960-25092377 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 thyroid gland: 2.0 seminal vesicle: 1.2 -AL365202.1 ENSG00000279745 9 3452305-3453987 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 23.6 epididymis: 9.5 -RP11-437B10.1 ENSG00000279765 15 92883413-92949230 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Expressed in all bone marrow: 244.2 -AL513523.2 ENSG00000279767 1 153772371-153774079 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Group enriched 5 epididymis: 13.7;skin: 3.5 prostate: 1.7 -AC008914.1 ENSG00000279768 5 55928640-55928741 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Expressed in all ovary: 78.7 -AC004813.1 ENSG00000279777 12 119918001-119918375 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Expressed in all testis: 38.8 -PPIAL4F ENSG00000279782 Peptidylprolyl isomerase A (cyclophilin A)-like 4F 1 144592868-144593527 Enzymes, Predicted intracellular proteins No evidence No evidence No evidence HPA058345 Uncertain Not detected adipose tissue: 0.0 -PRAMEF18 ENSG00000279804 PRAME family member 18 1 13222695-13226133 Predicted intracellular proteins No evidence No evidence HPA057423 Uncertain Not detected adipose tissue: 0.0 -AC018512.1 ENSG00000279808 15 43782843-43783033 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 6 epididymis: 52.5 parathyroid gland: 8.4 -CR392000.1 ENSG00000279813 9 136249978-136251205 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Group enriched 11 epididymis: 39.8;fallopian tube: 29.1 thyroid gland: 3.0 -AC010287.1 ENSG00000279816 16 58554337-58554935 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Mixed bone marrow: 2.7 -AC104389.2 ENSG00000279824 11 5248449-5249858 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 21 placenta: 2.6 liver: 0.1 -AL023875.1 ENSG00000279849 X 42285229-42285603 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Mixed skin: 14.5 -AL135842.1 ENSG00000279850 1 152511791-152512783 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC063956.1 ENSG00000279857 4 70020979-70021229 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AL356135.1 ENSG00000279892 6 61585946-61587035 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AP002962.1 ENSG00000279906 11 118025369-118029863 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed testis: 6.2 -AC110615.1 ENSG00000279909 4 75949920-75957413 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 14.6 skin: 7.3 -OR5AR1 ENSG00000279911 Olfactory receptor, family 5, subfamily AR, member 1 (gene/pseudogene) 11 56663686-56664618 G-protein coupled receptors, Predicted membrane proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -AC010655.1 ENSG00000279916 7 128441694-128442726 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected adipose tissue: 0.0 -AC017081.1 ENSG00000279921 2 206355739-206356119 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Mixed testis: 25.1 -FO538757.3 ENSG00000279928 1 182393-184158 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 10 testis: 3.5 bone marrow: 0.3 -AC073657.1 ENSG00000279937 15 41781148-41784031 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 11.5 bone marrow: 5.8 -OR10C1 hs6M1-17, OR10C1P, OR10C2 ENSG00000279941 Olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) 6 29440016-29440954 Predicted membrane proteins No evidence No evidence HPA049336 Uncertain Not detected adipose tissue: 0.0 -AL049872.1 ENSG00000279963 14 92070230-92071042 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -GVQW2 ENSG00000279968 GVQW motif containing 2 6 138725211-138773652 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 2.3 epididymis: 0.5 -BAGE5 ENSG00000279973 B melanoma antigen family, member 5 22 11066501-11068089 Predicted secreted proteins Evidence at transcript level Evidence at transcript level Tissue enriched 9 testis: 7.9 ovary: 0.9 -CH17-140K24.8 ENSG00000279983 5 141223372-141245861 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 1.5 endometrium: 0.8 -AC234582.2 ENSG00000279986 1 155188587-155189452 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Group enriched 5 esophagus: 6.9;fallopian tube: 6.0;gallbladder: 21.0;lung: 6.9;stomach: 30.2 kidney: 2.6 -AL022578.1 ENSG00000279988 X 47835953-47836793 Predicted membrane proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC022210.1 ENSG00000279992 2 84895085-84895221 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC009060.2 ENSG00000280006 16 70205400-70205780 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Expressed in all testis: 85.3 -AC109829.2 ENSG00000280034 2 27556908-27557282 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Not detected thyroid gland: 0.1 -AL133335.1 ENSG00000280041 20 54249953-54250327 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 parathyroid gland: 3.3;testis: 3.6 esophagus: 2.0 -AC008622.1 ENSG00000280050 19 46792971-46793189 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -CH507-9B2.3 ENSG00000280071 21 5079294-5128425 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level HPA018517 Uncertain Expressed in all kidney: 147.3 -U51561.1 ENSG00000280080 22 46915328-46915908 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA002539 Supported Tissue enriched 12 testis: 4.6 bone marrow: 0.3 -AC011155.1 ENSG00000280098 18 52409042-52409257 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected adipose tissue: 0.0 -AJ239318.1 ENSG00000280108 21 13305171-13314664 Predicted membrane proteins No evidence No evidence Not detected testis: 0.3 -AC123512.2 ENSG00000280112 12 91986682-91993403 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed lymph node: 3.1 -AL357140.1 ENSG00000280113 1 9827610-9828258 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 skin: 1.0 epididymis: 0.2 -AC231657.1 ENSG00000280116 X 49155242-49157351 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed parathyroid gland: 4.9 -AC055733.1 ENSG00000280127 3 130868872-130869246 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 bone marrow: 1.0 skin: 0.3 -AC073333.1 ENSG00000280130 7 16789242-16789622 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Expressed in all epididymis: 37.9 -AC016142.1 ENSG00000280141 3 150819598-150819972 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 parathyroid gland: 3.3;testis: 3.6 esophagus: 2.0 -AC026248.1 ENSG00000280151 8 128118011-128118385 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Expressed in all epididymis: 22.2 -PCDH20 FLJ22218, PCDH13 ENSG00000280165 Protocadherin 20 13 61409685-61415522 Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level Tissue enhanced 0 cerebral cortex: 14.6;smooth muscle: 12.8 lung: 5.0 -AP000687.1 ENSG00000280170 21 35898055-35898429 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 skin: 13.2 gallbladder: 8.6 -AL354828.2 ENSG00000280175 13 22664217-22675253 Predicted intracellular proteins No evidence No evidence Not detected spleen: 0.5 -AP000349.2 ENSG00000280178 22 23782283-23783958 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cervix, uterine: 2.2;endometrium: 4.0 smooth muscle: 1.6 -AL023806.1 ENSG00000280184 6 145789760-145791832 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 epididymis: 9.3 bone marrow: 3.1 -AC005477.1 ENSG00000280188 14 71965306-71966899 Predicted intracellular proteins No evidence No evidence Not detected epididymis: 0.0 -AC008686.1 ENSG00000280221 19 13780070-13790158 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed skeletal muscle: 6.6 -AC004824.2 ENSG00000280226 1 17329012-17331796 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed bone marrow: 6.4 -AL590235.1 ENSG00000280230 4 3538044-3538418 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Mixed cerebral cortex: 4.8 -AL049794.1 ENSG00000280240 20 16551149-16553012 Predicted intracellular proteins No evidence No evidence Not detected bone marrow: 0.6 -AC009060.3 ENSG00000280252 16 70224358-70224738 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Mixed thyroid gland: 11.8 -AC009758.1 ENSG00000280253 11 4367351-4368295 Predicted membrane proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC017028.10 ENSG00000280260 2 239161797-239162357 Predicted intracellular proteins No evidence No evidence HPA035506 Uncertain Not detected skeletal muscle: 0.4 -AC004158.1 ENSG00000280264 16 72496967-72497341 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Not detected parathyroid gland: 0.9 -PRAMEF26 ENSG00000280267 PRAME family member 26 1 13049476-13158092 Predicted intracellular proteins No evidence No evidence No evidence Not detected adipose tissue: 0.0 -AF131216.1 ENSG00000280273 8 11283500-11285068 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 38 testis: 37.0 cerebral cortex: 0.9 -AC007163.2 ENSG00000280298 2 200682822-200683196 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 adrenal gland: 2.7;spleen: 2.4;testis: 2.2 small intestine: 0.7 -AC006328.4 ENSG00000280301 Y 25463994-25473714 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.1 -AF111168.2 ENSG00000280308 14 77416398-77416772 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Mixed testis: 11.4 -AL365181.2 ENSG00000280316 1 156597173-156599410 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 4.5 epididymis: 1.6 -AC026449.1 ENSG00000280329 5 115855994-115858468 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC092159.1 ENSG00000280360 2 687799-688348 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected testis: 0.9 -CU104787.1 ENSG00000280363 22 11065974-11067346 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 21 testis: 2.0 epididymis: 0.0 -AL137860.1 ENSG00000280403 1 27064991-27065365 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Tissue enhanced 0 breast: 11.5;kidney: 9.5 duodenum: 7.1 -AC104073.2 ENSG00000280410 7 65140528-65141723 Predicted intracellular proteins No evidence No evidence HPA021548 Approved Nucleoplasm
Nuclear bodies Not detected testis: 0.6 -AC104057.1 ENSG00000280427 7 65554258-65555459 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA021548 Approved Nucleoplasm
Nuclear bodies Not detected cervix: 0.8 -CH507-9B2.9 ENSG00000280433 21 5155499-5165472 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed lymph node: 13.8 -AC109486.1 ENSG00000280447 5 60430738-60431112 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA042797 Uncertain Expressed in all appendix: 33.8 -AC100821.2 ENSG00000280473 8 53993605-53994438 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cervix, uterine: 5.0;rectum: 1.9 breast: 1.0 -AC010184.1 ENSG00000280530 3 141487181-141487424 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected adipose tissue: 0.0 -AC107081.1 ENSG00000280544 2 61929691-61930719 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 liver: 8.7 epididymis: 7.5 -AC131263.1 ENSG00000280550 11 33073925-33074214 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed skin: 8.4 -AC024361.1 ENSG00000280575 17 82718516-82718640 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 rectum: 1.1 fallopian tube: 0.5 -AC138028.1 ENSG00000280603 16 88686544-88687053 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 cerebral cortex: 21.4;epididymis: 12.5 bone marrow: 6.4 -AC245100.1 ENSG00000280649 1 148458814-148459871 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA071360 Uncertain Nucleoplasm
Nuclear bodies Mixed spleen: 13.9 -CCDC163P C1orf231, LOC126661 ENSG00000280670 Coiled-coil domain containing 163, pseudogene 1 45493866-45500079 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 parathyroid gland: 2.2 thyroid gland: 1.5 -AC112719.2 ENSG00000280671 4 75991788-75992048 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 spleen: 2.7;testis: 3.3 kidney: 0.6 -AC092384.1 ENSG00000280675 16 88827958-88828137 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 adipose tissue: 1.1;spleen: 1.0 colon: 0.9 -AC069499.1 ENSG00000280684 3 108585964-108586229 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC009121.2 ENSG00000280717 16 11345483-11345560 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC009950.1 ENSG00000280755 2 230176665-230221721 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA047036, HPA058554 Uncertain Approved Nucleus Mixed lymph node: 8.5 -CH17-270A2.2 ENSG00000280778 1 145927258-145977811 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.2 -PAGR1 C16orf53, GAS, MGC4606, PA1 ENSG00000280789 PAXIP1 associated glutamate-rich protein 1 16 29815952-29820117 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA041440, HPA043608 Uncertain Expressed in all ovary: 60.4 -AC018902.1 ENSG00000280817 15 52430064-52430768 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -RPS4Y2 RPS4Y2P ENSG00000280969 Ribosomal protein S4, Y-linked 2 Y 20756164-20781032 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA000857 Uncertain Group enriched 12 prostate: 3.3;testis: 2.2 tonsil: 0.2 -MATR3 ENSG00000280987 Matrin 3 5 139273752-139331677 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036564, HPA036565 Supported Approved Nucleoplasm Expressed in all cerebral cortex: 63.1 -RP11-717K11.2 ENSG00000281028 4 25160663-25277306 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA004099 Uncertain Uncertain Cytosol Mixed testis: 11.2 -RP4-777O23.3 ENSG00000281039 7 30497077-30550761 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA020735 Uncertain Mixed epididymis: 30.0 -AC013286.1 ENSG00000281042 10 76350749-76351228 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Group enriched 31 bone marrow: 1.3;epididymis: 4.7 adipose tissue: 0.0 -AC016734.1 ENSG00000281071 2 63609247-63610211 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC055866.1 ENSG00000281079 17 42993098-42993781 Predicted intracellular proteins No evidence No evidence Not detected epididymis: 0.0 -AC091180.1 ENSG00000281126 17 49408209-49408427 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 parathyroid gland: 24.1 tonsil: 12.9 -AC074033.1 ENSG00000281137 3 169483709-169483946 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 endometrium: 2.0 thyroid gland: 0.9 -AC087392.1 ENSG00000281182 17 775201-775574 Predicted intracellular proteins No evidence No evidence Not detected bone marrow: 0.7 -AC018867.1 ENSG00000281192 2 186501707-186502265 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 bone marrow: 13.1 thyroid gland: 4.1 -AC011380.1 ENSG00000281227 5 140287313-140289276 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC110602.1 ENSG00000281267 17 60659523-60660839 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed epididymis: 12.8 -AC087651.1 ENSG00000281273 17 74935426-74936187 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 82 small intestine: 8.2 adipose tissue: 0.0 -AL137164.1 ENSG00000281282 14 24968813-24969619 Predicted intracellular proteins No evidence No evidence Not detected kidney: 0.7 -AC016549.1 ENSG00000281325 5 14341288-14343089 Predicted membrane proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC016753.2 ENSG00000281331 2 85573870-85574886 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Mixed duodenum: 19.1 -AC104650.2 ENSG00000281359 4 8215292-8216501 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed appendix: 13.2 -AC079907.1 ENSG00000281370 12 102075068-102075229 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AL139333.1 ENSG00000281446 6 83072973-83073135 Predicted intracellular proteins No evidence No evidence Not detected esophagus: 0.9 -AC005042.1 ENSG00000281472 2 158551490-158552155 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC104581.1 ENSG00000281523 17 7920952-7921254 Predicted intracellular proteins No evidence No evidence Not detected epididymis: 0.0 -AC087350.1 ENSG00000281527 8 116849884-116851073 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 bone marrow: 88.0 appendix: 29.7 -AC241585.2 ENSG00000281571 1 145214851-145215938 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA071360 Uncertain Nucleoplasm
Nuclear bodies Mixed spleen: 21.3 -AC024060.1 ENSG00000281584 3 3145453-3145614 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 parathyroid gland: 9.5 salivary gland: 6.0 -AL133475.1 ENSG00000281602 6 80001402-80001907 Predicted intracellular proteins No evidence No evidence Not detected epididymis: 0.0 -RP11-506B6.7 ENSG00000281613 6 112236806-112350094 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA059324 Uncertain Tissue enriched 13 testis: 8.2 placenta: 0.6 -AC006445.1 ENSG00000281620 4 13627442-13627591 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC022819.2 ENSG00000281635 15 99319095-99319623 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 bone marrow: 1.7 rectum: 0.4 -AC073130.2 ENSG00000281656 7 116248600-116249422 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC087651.2 ENSG00000281674 17 75038085-75038357 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC012363.2 ENSG00000281676 2 120290710-120291049 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC241377.2 ENSG00000281741 1 120913151-120914238 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA071360 Uncertain Nucleoplasm
Nuclear bodies Mixed parathyroid gland: 8.2 -AL138751.1 ENSG00000281760 9 71897213-71897646 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AP001888.1 ENSG00000281781 11 69671952-69672075 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -FBF1 ALB, FBF-1, FLJ00103, KIAA1863 ENSG00000281844 Fas (TNFRSF6) binding factor 1 17 75910723-75938149 Predicted intracellular proteins Evidence at protein level No evidence Evidence at protein level Evidence at protein level HPA023677 Uncertain Approved Centrosome Not detected adipose tissue: 0.0 -AC105009.1 ENSG00000281855 8 140880336-140883127 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -AC126407.1 ENSG00000281873 15 23565857-23566366 Predicted intracellular proteins No evidence No evidence Not detected adipose tissue: 0.0 -GIMAP1-GIMAP5 ENSG00000281887 GIMAP1-GIMAP5 readthrough 7 150716668-150743646 Predicted membrane proteins Evidence at protein level Evidence at protein level HPA053441 Supported Endoplasmic reticulum Tissue enhanced 0 spleen: 18.3 appendix: 15.4 -AC073072.1 ENSG00000281889 7 22798447-22798979 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 2.4 skin: 1.7 -C1QTNF9B-AS1 ENSG00000281899 C1QTNF9B antisense RNA 1 13 24321126-24321428 Predicted intracellular proteins No evidence No evidence Not detected esophagus: 0.6 -TMEM265 ENSG00000281991 Transmembrane protein 265 16 30740381-30744281 Predicted membrane proteins Evidence at transcript level Evidence at transcript level No evidence Mixed skin: 18.9 -TMBIM4 ENSG00000282031 Transmembrane BAX inhibitor motif containing 4 12 66137960-66169896 Predicted membrane proteins Evidence at transcript level Evidence at transcript level Expressed in all epididymis: 77.8 -RP1-179P9.3 ENSG00000282218 6 117318211-117573571 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA019477 Uncertain Approved Golgi apparatus
Cytosol Not detected epididymis: 0.8 -RP11-295P9.13 ENSG00000282246 10 13610047-13655929 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA047950 Uncertain Mixed skin: 14.3 -RP11-231C18.3 ENSG00000282278 4 53377839-54295272 Predicted intracellular proteins Evidence at protein level Evidence at protein level HPA058202 Approved Nucleoplasm Tissue enhanced 0 appendix: 1.3;cerebral cortex: 3.3 ovary: 0.7 -CYP3A7-CYP3A51P ENSG00000282301 CYP3A7-CYP3A51P readthrough 7 99684957-99735102 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA072245 Uncertain Cytosol Tissue enhanced 0 liver: 7.4 gallbladder: 1.9 -RP5-1052M9.5 ENSG00000282419 X 124246249-124336862 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enriched 33 testis: 3.2 adipose tissue: 0.0 -ADORA3 AD026 ENSG00000282608 Adenosine A3 receptor 1 111499429-111503760 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level Mixed adrenal gland: 18.5 -C11orf71 FLJ20010 ENSG00000282682 Chromosome 11 open reading frame 71 11 114399960-114400331 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA063943, HPA074787 Approved Nucleoplasm Tissue enriched 11 testis: 44.1 skeletal muscle: 4.1 -RP3-369A17.6 ENSG00000282804 6 24797373-24809798 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.6 -RP13-147D17.3 ENSG00000282815 X 125320120-125325214 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 28 testis: 2.8 adipose tissue: 0.0 -ATRIP ENSG00000282827 ATR interacting protein 3 48446710-48467645 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA035437, HPA047590 Approved Approved Nucleus Mixed testis: 6.2 -RP11-96L14.8 ENSG00000282872 1 26164161-26168581 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Not detected testis: 0.7 -RP11-49P4.7 ENSG00000282881 1 46532166-46533614 Predicted membrane proteins No evidence No evidence Not detected cerebral cortex: 0.3 -AKR1C3 ENSG00000282883 Aldo-keto reductase family 1, member C3 10 5048812-5107503 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA068265 Approved Nucleus
Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Tissue enhanced 0 duodenum: 254.5;gallbladder: 246.9 small intestine: 168.3 -AL365273.1 ENSG00000282889 Ectonucleoside triphosphate diphosphohydrolase 1 10 95844477-95866383 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level Mixed smooth muscle: 17.8 -AC123512.3 ENSG00000282896 Uncharacterized protein C12orf79 12 91987578-91993403 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level No evidence Tissue enhanced 0 lymph node: 3.8 appendix: 2.1 -BLOC1S5 dJ303A1.3, MU, MUTED ENSG00000282913 Biogenesis of lysosomal organelles complex-1, subunit 5, muted 6 8015810-8064376 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA077525 Approved Vesicles Tissue enhanced 0 breast: 1.5 cervix: 1.4 -CTC-281F24.5 ENSG00000282936 17 6636780-6640316 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed cerebral cortex: 1.9 -RABL6 ENSG00000282955 RAB, member RAS oncogene family-like 6 9 136808197-136840522 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA044037, HPA050638 Uncertain Uncertain Nucleus
Centrosome
Cytosol Expressed in all esophagus: 20.2 -AL513412.1 ENSG00000282960 9 6720949-7076451 Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enhanced 0 fallopian tube: 1.7 endometrium: 0.9 -RP1-34B20.21 ENSG00000282988 6 26195595-26199293 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level HPA041189 Uncertain Tissue enhanced 0 bone marrow: 2.1 testis: 0.7 -RP11-511P7.5 ENSG00000283013 7 150400702-150412470 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed spleen: 8.0 -CAPS CAPS1, MGC126562 ENSG00000283027 Calcyphosine 19 5914407-5915322 Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA043520 Supported Supported Nucleus
Plasma membrane
Cytosol Tissue enriched 9 fallopian tube: 68.8 endometrium: 7.3 -KLF18 ENSG00000283039 Kruppel-like factor 18 1 44137821-44141631 Predicted intracellular proteins No evidence No evidence Not detected testis: 0.3 -RP11-736N17.11 ENSG00000283071 14 103084210-103090027 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 1.0 cerebral cortex: 0.5 -CTD-2331H12.8 ENSG00000283088 19 52880663-52962768 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Mixed parathyroid gland: 7.2 -RP11-141O19.1 ENSG00000283093 X 51681212-51682831 Predicted intracellular proteins Evidence at transcript level Evidence at transcript level Tissue enhanced 0 testis: 3.0 cerebral cortex: 0.8 diff -r 0b279190f90d -r 133309fd6875 proteore_protein_full_atlas.loc.sample --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/proteore_protein_full_atlas.loc.sample Fri Jan 24 04:22:48 2020 -0500 @@ -0,0 +1,2 @@ +# +9979818977 HPA_full_atlas_23-10-2018 HPA Full Protein Atlas 23/10/2018 HPA_full_atlas tool-data/HPA_full_atlas_23-10-2018.tsv diff -r 0b279190f90d -r 133309fd6875 tool-data/HPA_full_atlas_23-10-2018.tsv --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool-data/HPA_full_atlas_23-10-2018.tsv Fri Jan 24 04:22:48 2020 -0500 @@ -0,0 +1,19614 @@ +Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific RNA cell line category RNA CS RNA CS TPM +TSPAN6 T245, TM4SF6, TSPAN-6 ENSG00000000003 Tetraspanin 6 X 100627109-100639991 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004109 Approved Approved Cytosol Expressed in all Mixed fallopian tube: 102.1 Cell line enhanced NTERA-2: 165.6;RT4: 203.5 +TNMD BRICD4, ChM1L, myodulin, TEM, tendin ENSG00000000005 Tenomodulin X 100584802-100599885 Predicted membrane proteins Evidence at protein level HPA034961, HPA055634 Uncertain Mixed Tissue enhanced adipose tissue: 10.1;seminal vesicle: 33.2 breast: 4.3 Group enriched 19 HAP1: 6.2;NTERA-2: 14.2 +DPM1 CDGIE, MPDS ENSG00000000419 Dolichyl-phosphate mannosyltransferase subunit 1, catalytic 20 50934867-50958555 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA051818 Approved Liver cancer:1.94e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 80.5 Expressed in all +SCYL3 PACE-1, PACE1 ENSG00000000457 SCY1 like pseudokinase 3 1 169849631-169894267 Enzymes, Predicted intracellular proteins Evidence at protein level HPA005624 Approved Uncertain Nuclear bodies
Microtubules Urothelial cancer:8.85e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 24.6 Expressed in all +C1orf112 FLJ10706 ENSG00000000460 Chromosome 1 open reading frame 112 1 169662007-169854080 Predicted intracellular proteins Evidence at protein level HPA023778, HPA024451 Uncertain Approved Mitochondria Endometrial cancer:9.56e-5 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 25.0 testis: 18.6 Expressed in all +FGR c-fgr, p55c-fgr, SRC2 ENSG00000000938 FGR proto-oncogene, Src family tyrosine kinase 1 27612064-27635277 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002024 Enhanced Approved Plasma membrane
Aggresome Expressed in all Tissue enhanced appendix: 85.6;bone marrow: 137.0;spleen: 90.6 lung: 56.3 Cell line enhanced Daudi: 61.4;HMC-1: 25.8;U-266/70: 116.7 +CFH ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS ENSG00000000971 Complement factor H 1 196651878-196747504 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB016385, CAB016769, HPA038922, HPA049176, HPA053326 Supported Approved Vesicles Renal cancer:1.92e-6 (unfavourable) Tissue enriched Tissue enhanced liver: 839.5 gallbladder: 205.3 Cell line enhanced HHSteC: 100.0;RT4: 176.9 +FUCA2 dJ20N2.5, MGC1314 ENSG00000001036 Fucosidase, alpha-L- 2, plasma 6 143494811-143511690 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031659, HPA031660, HPA031661 Uncertain Liver cancer:2.70e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 154.2 Mixed +GCLC GCS, GLCL, GLCLC ENSG00000001084 Glutamate-cysteine ligase catalytic subunit 6 53497341-53616970 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009569, HPA036359, HPA036360 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:3.83e-6 (favourable), Thyroid cancer:8.24e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 80.9 Expressed in all +NFYA CBF-B, HAP2, NF-YA ENSG00000001167 Nuclear transcription factor Y subunit alpha 6 41072945-41099976 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009250, HPA050779 Enhanced Enhanced Nucleoplasm Liver cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all testis: 70.9 Expressed in all +STPG1 C1orf201, FLJ33340, MAPO2 ENSG00000001460 Sperm tail PG-rich repeat containing 1 1 24356999-24416934 Predicted intracellular proteins Evidence at protein level HPA024301 Approved Nucleoplasm Endometrial cancer:1.33e-4 (favourable), Renal cancer:2.31e-4 (favourable) Mixed Tissue enhanced testis: 46.9 fallopian tube: 26.8 Mixed +NIPAL3 DJ462O23.2, NPAL3 ENSG00000001461 NIPA like domain containing 3 1 24415794-24472976 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039978 Approved Approved Nucleoplasm Renal cancer:3.03e-7 (favourable), Thyroid cancer:3.95e-4 (favourable) Expressed in all Expressed in all prostate: 97.4 Mixed +LAS1L FLJ12525 ENSG00000001497 LAS1 like, ribosome biogenesis factor X 65512582-65534775 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044431, HPA061463 Supported Approved Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all Expressed in all parathyroid gland: 40.6 Expressed in all +ENPP4 KIAA0879, NPP4 ENSG00000001561 Ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 6 46129993-46146699 Enzymes, Predicted membrane proteins Evidence at protein level HPA016594 Approved Renal cancer:6.95e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 38.4 Cell line enhanced SCLC-21H: 21.1 +SEMA3F Sema4, SEMAK ENSG00000001617 Semaphorin 3F 3 50155045-50189075 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035008 Approved Liver cancer:5.15e-4 (unfavourable) Expressed in all Expressed in all skin: 89.1 Cell line enhanced HUVEC TERT2: 156.4;SK-BR-3: 129.8;TIME: 276.8 +CFTR ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR ENSG00000001626 Cystic fibrosis transmembrane conductance regulator 7 117465784-117715971 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB001951, HPA021939 Enhanced Liver cancer:9.44e-4 (unfavourable) Tissue enhanced Tissue enhanced gallbladder: 89.3 rectum: 49.0 Group enriched 19 CACO-2: 26.2;MOLT-4: 97.6;U-266/70: 47.9 +ANKIB1 DKFZP434A0225, KIAA1386 ENSG00000001629 Ankyrin repeat and IBR domain containing 1 7 92246234-92401384 Predicted intracellular proteins Evidence at protein level HPA019358, HPA021780 Uncertain Supported Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 46.3 Expressed in all +CYP51A1 CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1 ENSG00000001630 Cytochrome P450 family 51 subfamily A member 1 7 92112151-92142952 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041325, HPA043508 Enhanced Enhanced Endoplasmic reticulum Cervical cancer:6.12e-4 (unfavourable) Expressed in all Expressed in all testis: 174.1 Expressed in all +KRIT1 CAM, CCM1 ENSG00000001631 KRIT1, ankyrin repeat containing 7 92198969-92246166 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049606 Supported Uncertain Vesicles Expressed in all Expressed in all testis: 48.7 Expressed in all +RAD52 ENSG00000002016 RAD52 homolog, DNA repair protein 12 912077-990053 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA028957 Approved Nuclear speckles
Plasma membrane Renal cancer:2.22e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 13.0 Expressed in all +BAD BBC2, BCL2L8 ENSG00000002330 BCL2 associated agonist of cell death 11 64269830-64284704 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004205, HPA028185, HPA062105 Approved Enhanced Mitochondria Expressed in all Expressed in all cerebral cortex: 48.9 Expressed in all +LAP3 LAP, LAPEP, PEPS ENSG00000002549 Leucine aminopeptidase 3 4 17577192-17607972 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029606, HPA029607 Enhanced Supported Nucleoplasm
Midbody
Cytosol Expressed in all Expressed in all appendix: 176.5 Mixed +CD99 MIC2 ENSG00000002586 CD99 molecule X 2691179-2741309 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000020, HPA035304 Supported Approved Golgi apparatus Renal cancer:5.87e-7 (unfavourable) Expressed in all Expressed in all gallbladder: 375.1 Mixed +HS3ST1 3OST1 ENSG00000002587 Heparan sulfate-glucosamine 3-sulfotransferase 1 4 11393150-11429765 Enzymes, Predicted secreted proteins Evidence at protein level HPA002237 Approved Approved Vesicles Renal cancer:5.99e-8 (favourable), Endometrial cancer:7.73e-4 (favourable), Urothelial cancer:8.67e-4 (favourable) Mixed Tissue enhanced gallbladder: 13.9;ovary: 23.2 urinary bladder: 5.6 Cell line enhanced CAPAN-2: 12.2;RPTEC TERT1: 9.1;RT4: 8.0;SCLC-21H: 4.3 +AOC1 ABP1, DAO ENSG00000002726 Amine oxidase, copper containing 1 7 150824627-150861504 Enzymes, Predicted secreted proteins Evidence at protein level HPA031032, HPA031033 Approved Prostate cancer:1.71e-4 (favourable) Group enriched Tissue enhanced placenta: 716.9;small intestine: 247.6 duodenum: 183.2 Cell line enhanced CAPAN-2: 17.4;HaCaT: 5.4;THP-1: 17.8 +WNT16 ENSG00000002745 Wnt family member 16 7 121325367-121341104 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA027030 Uncertain Mixed Group enriched 7 cervix, uterine: 8.6;skin: 24.3 seminal vesicle: 2.5 Cell line enhanced CAPAN-2: 2.0;HEK 293: 4.9;hTEC/SVTERT24-B: 1.6;U-2197: 2.4 +HECW1 KIAA0322, NEDL1 ENSG00000002746 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 7 43112599-43566001 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007203, HPA007593, HPA007609 Approved Supported Cytosol Not detected Tissue enhanced cerebral cortex: 10.9;kidney: 8.2 testis: 3.4 Cell line enhanced A549: 3.9;U-266/70: 9.1 +MAD1L1 HsMAD1, MAD1, PIG9, TP53I9, TXBP181 ENSG00000002822 MAD1 mitotic arrest deficient like 1 7 1815793-2233243 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003635, CAB015338 Supported Supported Nucleoplasm
Nuclear membrane Expressed in all Expressed in all lymph node: 23.3 Expressed in all +LASP1 Lasp-1, MLN50 ENSG00000002834 LIM and SH3 protein 1 17 38869859-38921770 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012072, CAB022049 Enhanced Supported Plasma membrane
Focal adhesion sites
Cytosol Liver cancer:2.41e-4 (unfavourable), Endometrial cancer:4.57e-4 (unfavourable) Expressed in all Expressed in all small intestine: 181.3 Expressed in all +SNX11 ENSG00000002919 Sorting nexin 11 17 48103357-48123074 Predicted intracellular proteins Evidence at protein level HPA044787, HPA054660 Approved Approved Cytosol Expressed in all Expressed in all thyroid gland: 32.1 Expressed in all +TMEM176A HCA112, MS4B1 ENSG00000002933 Transmembrane protein 176A 7 150800403-150805120 Predicted membrane proteins Evidence at protein level HPA008770 Approved Approved Mitochondria Expressed in all Expressed in all liver: 583.9 Cell line enriched 30 HSkMC: 493.9 +M6PR CD-M6PR, CD-MPR ENSG00000003056 Mannose-6-phosphate receptor, cation dependent 12 8940363-8949955 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB034464, HPA040445 Approved Liver cancer:3.89e-4 (unfavourable) Expressed in all Expressed in all spleen: 175.3 Expressed in all +KLHL13 BKLHD2, FLJ10262, KIAA1309 ENSG00000003096 Kelch like family member 13 X 117897813-118117340 Predicted intracellular proteins Evidence at protein level HPA046039, HPA059901 Approved Approved Cytosol Mixed Tissue enhanced endometrium: 52.6 smooth muscle: 43.9 Cell line enhanced HeLa: 40.3;RPTEC TERT1: 80.3;SH-SY5Y: 100.1 +CYP26B1 P450RAI-2 ENSG00000003137 Cytochrome P450 family 26 subfamily B member 1 2 72129238-72148038 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012567 Uncertain Approved Cytosol Expressed in all Tissue enhanced testis: 27.1 skin: 25.0 Cell line enhanced HaCaT: 13.4;RH-30: 18.5;U-2 OS: 21.9 +ICA1 ICA69, ICAp69 ENSG00000003147 Islet cell autoantigen 1 7 8113184-8262687 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017646, HPA061452 Approved Supported Vesicles
Cytosol Renal cancer:4.23e-8 (favourable) Expressed in all Mixed testis: 42.6 Cell line enhanced SCLC-21H: 73.0;SH-SY5Y: 109.7 +DBNDD1 FLJ12582, MGC3101 ENSG00000003249 Dysbindin domain containing 1 16 90004865-90020128 Predicted intracellular proteins Evidence at protein level HPA043018 Approved Approved Nuclear speckles
Cytosol Renal cancer:2.75e-7 (favourable) Expressed in all Tissue enhanced cerebral cortex: 24.0 skeletal muscle: 15.6 Cell line enhanced MCF7: 109.1 +ALS2 ALS2CR6 ENSG00000003393 ALS2, alsin Rho guanine nucleotide exchange factor 2 201700554-201781189 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046588 Approved Approved Intermediate filaments
Cytosol Expressed in all Expressed in all cerebral cortex: 16.6 Expressed in all +CASP10 MCH4 ENSG00000003400 Caspase 10 2 201182881-201229406 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003780, HPA017059 Approved Approved Golgi apparatus
Vesicles Renal cancer:6.05e-7 (unfavourable), Liver cancer:8.54e-4 (unfavourable) Expressed in all Mixed spleen: 24.1 Cell line enhanced HUVEC TERT2: 21.4 +CFLAR c-FLIP, CASH, CASP8AP1, Casper, CLARP, FLAME, FLIP, I-FLICE, MRIT ENSG00000003402 CASP8 and FADD like apoptosis regulator 2 201116104-201176687 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA019044, CAB022157, CAB025216 Uncertain Supported Nucleus
Nuclear bodies
Plasma membrane
Cytosol Head and neck cancer:2.79e-4 (favourable) Expressed in all Expressed in all bone marrow: 159.9 Expressed in all +TFPI EPI, LACI, TFI, TFPI1 ENSG00000003436 Tissue factor pathway inhibitor 2 187464230-187565760 Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA005575, CAB020842 Supported Approved Intermediate filaments
Cytosol Cervical cancer:2.02e-4 (unfavourable) Expressed in all Expressed in all placenta: 267.0 Cell line enhanced HHSteC: 309.8;HUVEC TERT2: 601.4;LHCN-M2: 367.6;TIME: 354.9 +NDUFAF7 C2orf56, MidA, PRO1853 ENSG00000003509 NADH:ubiquinone oxidoreductase complex assembly factor 7 2 37231631-37253403 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045217 Uncertain Liver cancer:1.48e-4 (unfavourable), Lung cancer:3.08e-4 (favourable) Expressed in all Tissue enriched 5 testis: 69.1 adrenal gland: 12.9 Expressed in all +RBM5 H37, LUCA15 ENSG00000003756 RNA binding motif protein 5 3 50088908-50119021 Predicted intracellular proteins Evidence at protein level HPA017335, HPA018011 Approved Enhanced Nucleoplasm Lung cancer:6.46e-4 (favourable), Pancreatic cancer:7.58e-4 (favourable), Liver cancer:9.77e-4 (unfavourable) Expressed in all Expressed in all endometrium: 112.7 Expressed in all +MTMR7 ENSG00000003987 Myotubularin related protein 7 8 17298030-17413528 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 22.9;parathyroid gland: 15.2 thyroid gland: 5.5 Cell line enhanced SCLC-21H: 12.4;SH-SY5Y: 6.5 +SLC7A2 ATRC2, CAT-2, HCAT2 ENSG00000003989 Solute carrier family 7 member 2 8 17497088-17570573 Predicted membrane proteins, Transporters Evidence at protein level HPA009277 Supported Plasma membrane
Cell Junctions Renal cancer:2.65e-7 (unfavourable), Stomach cancer:3.08e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 380.7 liver: 92.6 Cell line enhanced HHSteC: 171.6 +ARF5 ENSG00000004059 ADP ribosylation factor 5 7 127588345-127591705 Plasma proteins, Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all skin: 176.2 Expressed in all +SARM1 KIAA0524, SAMD2, SARM ENSG00000004139 Sterile alpha and TIR motif containing 1 17 28364356-28404049 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA024359, HPA024759 Uncertain Approved Vesicles Mixed Mixed duodenum: 7.5 Cell line enhanced CACO-2: 26.9 +POLDIP2 DKFZP586F1524, PDIP38 ENSG00000004142 DNA polymerase delta interacting protein 2 17 28347177-28357522 Predicted intracellular proteins Evidence at protein level HPA007700 Approved Mitochondria Expressed in all Expressed in all kidney: 109.1 Expressed in all +PLXND1 KIAA0620 ENSG00000004399 Plexin D1 3 129555175-129606818 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB020819 Approved Renal cancer:5.93e-7 (unfavourable) Expressed in all Expressed in all placenta: 161.3 Cell line enhanced ASC diff: 268.0;HSkMC: 206.8;HUVEC TERT2: 287.4;TIME: 332.2 +AK2 ENSG00000004455 Adenylate kinase 2 1 33007940-33080996 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018479 Approved Breast cancer:4.37e-4 (favourable), Pancreatic cancer:6.40e-4 (unfavourable), Endometrial cancer:8.65e-4 (unfavourable), Liver cancer:9.32e-4 (unfavourable) Expressed in all Expressed in all kidney: 183.3 Expressed in all +CD38 ENSG00000004468 CD38 molecule 4 15778275-15853230 Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins Evidence at protein level CAB002493, HPA022132, CAB025255, HPA052381 Enhanced Supported Plasma membrane Endometrial cancer:9.68e-4 (favourable) Expressed in all Mixed seminal vesicle: 27.6 Cell line enhanced Daudi: 91.6;Karpas-707: 24.9;MOLT-4: 26.4;REH: 23.7;U-266/70: 20.4 +FKBP4 FKBP52, FKBP59 ENSG00000004478 FK506 binding protein 4 12 2794953-2805423 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006148, CAB017441, HPA062857 Enhanced Enhanced Nucleoplasm
Cytosol Liver cancer:6.12e-5 (unfavourable), Lung cancer:1.44e-4 (unfavourable), Endometrial cancer:7.65e-4 (unfavourable) Expressed in all Expressed in all testis: 107.4 Expressed in all +KDM1A AOF2, BHC110, KDM1, KIAA0601, LSD1 ENSG00000004487 Lysine demethylase 1A 1 23019448-23083689 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB005884, HPA053660 Supported Enhanced Nucleoplasm
Cytosol Liver cancer:4.47e-12 (unfavourable), Colorectal cancer:6.31e-4 (favourable) Expressed in all Expressed in all testis: 163.3 Expressed in all +RBM6 3G2, DEF-3, DEF3, g16, NY-LU-12 ENSG00000004534 RNA binding motif protein 6 3 49940007-50100045 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026272, HPA027164 Enhanced Approved Nuclear speckles
Cytoplasmic bodies Urothelial cancer:5.13e-5 (favourable), Pancreatic cancer:1.41e-4 (favourable), Renal cancer:8.83e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 83.7 Expressed in all +CAMKK1 CAMKKA, DKFZp761M0423, MGC34095 ENSG00000004660 Calcium/calmodulin dependent protein kinase kinase 1 17 3860315-3894891 Enzymes, Predicted intracellular proteins Evidence at protein level CAB009111, HPA028062 Approved Supported Cytosol Pancreatic cancer:2.65e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 51.5 seminal vesicle: 14.7 Cell line enhanced U-87 MG: 27.3 +RECQL RecQ1, RecQL1 ENSG00000004700 RecQ like helicase 12 21468911-21501669 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009743, HPA030960, HPA064259 Enhanced Enhanced Nucleoplasm Ovarian cancer:3.15e-4 (unfavourable) Expressed in all Expressed in all lymph node: 51.1 Expressed in all +VPS50 CCDC132, DKFZp313I2429, FLJ20097, KIAA1861, VPS54L ENSG00000004766 VPS50, EARP/GARPII complex subunit 7 93232340-93361121 Predicted intracellular proteins Evidence at protein level HPA026679 Approved Uncertain Plasma membrane
Cytosol Renal cancer:1.35e-6 (favourable), Liver cancer:7.21e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 25.4 Expressed in all +HSPB6 FLJ32389, Hsp20, PPP1R91 ENSG00000004776 Heat shock protein family B (small) member 6 19 35754569-35758079 Predicted intracellular proteins Evidence at protein level CAB001974, HPA044153, HPA054811 Enhanced Urothelial cancer:1.43e-6 (unfavourable), Renal cancer:1.93e-5 (unfavourable) Expressed in all Tissue enhanced skeletal muscle: 843.0 adipose tissue: 666.5 Cell line enhanced ASC diff: 1220.3;ASC TERT1: 521.5;HHSteC: 505.3;HSkMC: 510.5 +ARHGAP33 FLJ39019, SNX26, TCGAP ENSG00000004777 Rho GTPase activating protein 33 19 35774532-35788822 Predicted intracellular proteins Evidence at protein level HPA030117, HPA030118 Supported Approved Plasma membrane
Actin filaments
Cytosol Renal cancer:3.09e-8 (unfavourable) Expressed in all Mixed cerebral cortex: 25.8 Cell line enhanced HMC-1: 50.9 +NDUFAB1 ACP, ACP1, FASN2A, SDAP ENSG00000004779 NADH:ubiquinone oxidoreductase subunit AB1 16 23581002-23596356 Predicted intracellular proteins Evidence at protein level HPA054364 Uncertain Supported Nucleoplasm
Mitochondria Renal cancer:1.94e-7 (favourable) Expressed in all Expressed in all heart muscle: 179.6 Expressed in all +PDK4 ENSG00000004799 Pyruvate dehydrogenase kinase 4 7 95583499-95596491 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056731 Approved Stomach cancer:1.80e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 763.0 Cell line enriched 7 ASC diff: 333.3 +SLC22A16 CT2, FLIPT2, OAT6, OKB1 ENSG00000004809 Solute carrier family 22 member 16 6 110424687-110476641 Predicted membrane proteins Evidence at protein level HPA036902 Uncertain Tissue enriched Group enriched 8 bone marrow: 12.9;parathyroid gland: 16.3;testis: 38.6 smooth muscle: 2.7 Group enriched 16 NB-4: 10.5;REH: 14.0;THP-1: 35.6;U-937: 24.4 +ZMYND10 BLU, CILD22 ENSG00000004838 Zinc finger MYND-type containing 10 3 50341110-50346852 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035255 Approved Plasma membrane
Cytosol Renal cancer:6.75e-5 (favourable) Tissue enhanced Group enriched 16 fallopian tube: 231.5;testis: 284.6 lung: 15.8 Cell line enhanced T-47d: 6.1;U-87 MG: 4.3 +ABCB5 ABCB5alpha, ABCB5beta, EST422562 ENSG00000004846 ATP binding cassette subfamily B member 5 7 20615207-20777038 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Tissue enriched 7 epididymis: 32.3 gallbladder: 4.3 Cell line enriched 6 SK-MEL-30: 37.0 +ARX CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS ENSG00000004848 Aristaless related homeobox X 25003694-25016420 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Endometrial cancer:3.54e-7 (unfavourable) Mixed Tissue enriched 7 ovary: 97.7 testis: 14.0 Cell line enhanced HAP1: 2.0;PC-3: 3.6;U-266/70: 6.3 +SLC25A13 ARALAR2, CITRIN, CTLN2 ENSG00000004864 Solute carrier family 25 member 13 7 96120220-96322147 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA018997 Approved Supported Mitochondria Renal cancer:9.14e-4 (favourable) Expressed in all Expressed in all liver: 77.3 Mixed +ST7 ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7 ENSG00000004866 Suppression of tumorigenicity 7 7 116953238-117230103 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038325, HPA038326 Approved Supported Nucleoplasm
Cytosol Renal cancer:3.39e-5 (favourable) Expressed in all Expressed in all thyroid gland: 51.0 Mixed +CDC27 ANAPC3, APC3, D0S1430E, D17S978E, NUC2 ENSG00000004897 Cell division cycle 27 17 47117703-47189422 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016315, HPA028129, HPA052399 Supported Enhanced Nucleoplasm Renal cancer:6.39e-5 (unfavourable), Colorectal cancer:1.77e-4 (favourable), Liver cancer:4.38e-4 (unfavourable), Lung cancer:8.15e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 71.5 Expressed in all +SLC4A1 AE1, CD233, DI, EPB3, FR, RTA1A, SW, WD, WR ENSG00000004939 Solute carrier family 4 member 1 (Diego blood group) 17 44248385-44268141 Blood group antigen proteins, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA015584, CAB034438, HPA063911 Enhanced Tissue enriched Tissue enriched 8 bone marrow: 238.0 kidney: 30.0 Mixed +CALCR CTR ENSG00000004948 Calcitonin receptor 7 93424487-93574730 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA028962, HPA061428 Enhanced Tissue enriched Tissue enhanced kidney: 2.1;testis: 1.4 placenta: 1.0 Cell line enhanced RPTEC TERT1: 1.5;T-47d: 3.6 +HCCS CCHL, MLS ENSG00000004961 Holocytochrome c synthase X 11111301-11123078 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA002946 Approved Enhanced Mitochondria Renal cancer:6.17e-8 (favourable), Liver cancer:1.35e-5 (unfavourable), Breast cancer:8.69e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 31.5 Expressed in all +DVL2 ENSG00000004975 Dishevelled segment polarity protein 2 17 7225341-7234545 Predicted intracellular proteins Evidence at protein level CAB009312, HPA021611, HPA022914, HPA064732 Approved Enhanced Nucleoplasm
Nuclear bodies Liver cancer:4.34e-6 (unfavourable), Pancreatic cancer:3.85e-4 (favourable) Expressed in all Expressed in all ovary: 36.1 Expressed in all +PRSS22 BSSP-4, hBSSP-4, SP001LA ENSG00000005001 Protease, serine 22 16 2852727-2858170 Enzymes, Predicted secreted proteins Evidence at protein level HPA049161 Approved Approved Nucleoplasm Mixed Tissue enhanced esophagus: 7.7;stomach: 11.1 salivary gland: 3.1 Cell line enhanced CAPAN-2: 67.3;SK-BR-3: 14.6;T-47d: 16.5 +UPF1 HUPF1, KIAA0221, NORF1, pNORF1, RENT1, smg-2 ENSG00000005007 UPF1, RNA helicase and ATPase 19 18831938-18868236 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019587, HPA020857 Approved Supported Nucleoplasm Renal cancer:2.97e-6 (favourable), Melanoma:2.72e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 56.7 Expressed in all +SKAP2 RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R ENSG00000005020 Src kinase associated phosphoprotein 2 7 26667062-26995239 Predicted intracellular proteins Evidence at protein level HPA005560, HPA024045 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 54.6 Cell line enhanced CAPAN-2: 125.0 +SLC25A5 2F1, ANT2, T2, T3 ENSG00000005022 Solute carrier family 25 member 5 X 119468400-119471319 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA046835, HPA071684 Approved Supported Mitochondria Renal cancer:8.06e-6 (favourable), Cervical cancer:7.35e-4 (favourable), Colorectal cancer:7.47e-4 (favourable) Expressed in all Expressed in all duodenum: 769.6 Expressed in all +MCUB CCDC109B, FLJ20647 ENSG00000005059 Mitochondrial calcium uniporter dominant negative beta subunit 4 109560205-109688726 Predicted membrane proteins, Transporters Evidence at protein level HPA048776 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:7.35e-6 (unfavourable) Expressed in all Mixed lymph node: 36.2 Mixed +HOXA11 HOX1, HOX1I ENSG00000005073 Homeobox A11 7 27181510-27185223 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006770, HPA035623 Enhanced Supported Nucleoplasm Renal cancer:2.57e-5 (unfavourable) Mixed Tissue enhanced endometrium: 96.3;smooth muscle: 68.5 cervix, uterine: 17.9 Cell line enhanced HEK 293: 46.1;U-937: 37.5 +POLR2J hRPB14, POLR2J1, RPB11, RPB11A, RPB11m ENSG00000005075 RNA polymerase II subunit J 7 102473118-102478907 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA042997, HPA044010, HPA046970 Approved Approved Nucleoplasm Expressed in all Expressed in all adrenal gland: 72.4 Expressed in all +DHX33 DDX33, DKFZp762F2011, FLJ21972 ENSG00000005100 DEAH-box helicase 33 17 5440912-5469060 Enzymes, Predicted intracellular proteins Evidence at protein level HPA073875 Supported Nucleoli Prostate cancer:6.10e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 13.6 Expressed in all +MEOX1 MOX1 ENSG00000005102 Mesenchyme homeobox 1 17 43640388-43661954 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045214 Uncertain Uncertain Nucleoli
Mitochondria Mixed Tissue enhanced adipose tissue: 25.3 spleen: 16.4 Cell line enriched 10 HeLa: 16.8 +THSD7A KIAA0960 ENSG00000005108 Thrombospondin type 1 domain containing 7A 7 11370357-11832198 Predicted membrane proteins Evidence at protein level HPA000923 Supported Renal cancer:2.24e-6 (favourable) Mixed Mixed kidney: 8.4 Cell line enhanced A549: 9.2;HUVEC TERT2: 5.6;REH: 6.5;SH-SY5Y: 10.8;THP-1: 12.8 +LIG3 LIG2 ENSG00000005156 DNA ligase 3 17 34980494-35009743 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006723 Supported Supported Nucleoplasm Expressed in all Expressed in all testis: 38.7 Expressed in all +RPAP3 FLJ21908, spag ENSG00000005175 RNA polymerase II associated protein 3 12 47661249-47706061 Predicted intracellular proteins Evidence at protein level HPA038311, HPA038312 Enhanced Approved Cytosol Liver cancer:2.01e-5 (unfavourable) Expressed in all Expressed in all lymph node: 34.4 Expressed in all +ACSM3 SA, SAH ENSG00000005187 Acyl-CoA synthetase medium-chain family member 3 16 20610243-20797581 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041013 Uncertain Renal cancer:9.88e-6 (favourable), Ovarian cancer:1.97e-4 (favourable) Mixed Tissue enhanced liver: 93.2 kidney: 90.8 Group enriched 12 HEL: 85.7;HMC-1: 339.4;K-562: 258.6 +AC004381.6 ENSG00000005189 Putative RNA exonuclease NEF-sp 16 20806429-20849668 Predicted intracellular proteins Evidence at protein level HPA040755, HPA040868 Enhanced Approved Nuclear membrane
Nucleoli
Endoplasmic reticulum Expressed in all Tissue enriched 33 testis: 618.5 parathyroid gland: 18.9 Mixed +CIAPIN1 Anamorsin ENSG00000005194 Cytokine induced apoptosis inhibitor 1 16 57428169-57447528 Predicted intracellular proteins Evidence at protein level HPA041350, HPA042182 Enhanced Supported Mitochondria Head and neck cancer:4.35e-4 (unfavourable), Renal cancer:4.42e-4 (favourable) Expressed in all Expressed in all testis: 129.0 Expressed in all +SPPL2B IMP4, KIAA1532, PSL1 ENSG00000005206 Signal peptide peptidase like 2B 19 2328615-2354806 Enzymes, Predicted membrane proteins Evidence at protein level CAB005592, HPA039292 Approved Approved Nucleoplasm
Plasma membrane
Centrosome Endometrial cancer:5.00e-5 (favourable), Pancreatic cancer:1.33e-4 (favourable), Renal cancer:6.45e-4 (unfavourable) Expressed in all Expressed in all testis: 49.1 Expressed in all +FAM214B bA182N22.6, FLJ11560, KIAA1539 ENSG00000005238 Family with sequence similarity 214 member B 9 35104112-35116341 Predicted intracellular proteins Evidence at protein level HPA048831, HPA055751 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all Expressed in all bone marrow: 24.5 Mixed +COPZ2 MGC23008 ENSG00000005243 Coatomer protein complex subunit zeta 2 17 48026167-48038030 Predicted intracellular proteins Evidence at protein level HPA055999 Uncertain Renal cancer:3.45e-9 (unfavourable), Thyroid cancer:2.89e-6 (unfavourable), Urothelial cancer:4.66e-4 (unfavourable) Expressed in all Mixed adipose tissue: 73.1 Cell line enhanced ASC TERT1: 132.1;fHDF/TERT166: 213.5 +PRKAR2B PRKAR2 ENSG00000005249 Protein kinase cAMP-dependent type II regulatory subunit beta 7 107044649-107161811 Predicted intracellular proteins Evidence at protein level HPA008421 Enhanced Approved Golgi apparatus
Centrosome
Mitochondria
Cytosol Pancreatic cancer:4.03e-4 (favourable), Colorectal cancer:6.38e-4 (favourable), Thyroid cancer:8.74e-4 (unfavourable) Mixed Tissue enhanced adipose tissue: 139.4 adrenal gland: 39.1 Cell line enhanced AN3-CA: 64.4;Daudi: 70.1;U-698: 172.6 +MSL3 MSL3L1 ENSG00000005302 Male-specific lethal 3 homolog (Drosophila) X 11758159-11775753 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034535, HPA034536 Uncertain Approved Nucleoplasm Renal cancer:3.14e-9 (unfavourable), Urothelial cancer:2.17e-4 (favourable), Head and neck cancer:3.28e-4 (favourable), Liver cancer:4.93e-4 (unfavourable) Expressed in all Expressed in all lymph node: 59.8 Expressed in all +CREBBP CBP, KAT3A, RSTS, RTS ENSG00000005339 CREB binding protein 16 3725054-3880726 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004212, HPA055861 Enhanced Enhanced Nucleoplasm
Nuclear bodies Renal cancer:6.24e-5 (favourable) Expressed in all Expressed in all testis: 61.7 Expressed in all +TSPOAP1 BZRAP1, KIAA0612, PRAX-1, RIM-BP1, RIMBP1 ENSG00000005379 TSPO associated protein 1 17 58301228-58328760 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024662, HPA025244 Enhanced Pancreatic cancer:9.15e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 69.1 Cell line enhanced HDLM-2: 164.7;HL-60: 51.5;REH: 119.1 +MPO ENSG00000005381 Myeloperoxidase 17 58269856-58280935 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000059, HPA021147, HPA061464 Enhanced Supported Nucleus
Vesicles Tissue enhanced Tissue enriched 82 bone marrow: 2499.6 salivary gland: 30.6 Group enriched 98 HL-60: 2786.8;NB-4: 2892.7 +PON1 ESA, PON ENSG00000005421 Paraoxonase 1 7 95297676-95324707 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level HPA001610 Uncertain Liver cancer:7.24e-7 (favourable) Tissue enriched Tissue enriched 69 liver: 233.6 adrenal gland: 3.3 Not detected +GCFC2 C2orf3, DNABF, GCF, TCF9 ENSG00000005436 GC-rich sequence DNA-binding factor 2 2 75652000-75710989 Predicted intracellular proteins Evidence at protein level HPA077882 Supported Nucleoplasm Thyroid cancer:3.09e-4 (unfavourable), Endometrial cancer:9.59e-4 (unfavourable) Expressed in all Expressed in all skin: 17.0 Expressed in all +WDR54 FLJ12953 ENSG00000005448 WD repeat domain 54 2 74421678-74425755 Predicted intracellular proteins Evidence at protein level HPA043257, HPA053558 Enhanced Approved Vesicles
Cytosol Expressed in all Tissue enhanced fallopian tube: 113.2 testis: 48.2 Expressed in all +CROT COT ENSG00000005469 Carnitine O-octanoyltransferase 7 87345681-87399795 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA019052, HPA019364, HPA019365 Enhanced Supported Vesicles Renal cancer:2.55e-6 (favourable), Urothelial cancer:4.02e-4 (favourable) Expressed in all Expressed in all thyroid gland: 68.4 Cell line enhanced RT4: 57.9 +ABCB4 GBD1, MDR2, MDR3, PFIC-3, PGY3 ENSG00000005471 ATP binding cassette subfamily B member 4 7 87401697-87480435 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA049395, HPA053288 Approved Approved Nucleoplasm
Plasma membrane
Actin filaments
Focal adhesion sites Tissue enriched Tissue enriched 6 liver: 69.3 adrenal gland: 10.7 Group enriched 6 SH-SY5Y: 14.2;WM-115: 25.6 +KMT2E HDCMC04P, MLL5 ENSG00000005483 Lysine methyltransferase 2E 7 105014179-105114361 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA022812, HPA056125 Approved Approved Renal cancer:3.80e-5 (unfavourable) Expressed in all Expressed in all endometrium: 51.7 Expressed in all +RHBDD2 NPD007, RHBDL7 ENSG00000005486 Rhomboid domain containing 2 7 75842602-75888926 Enzymes, Predicted membrane proteins Evidence at protein level HPA045074, HPA051960 Uncertain Enhanced Golgi apparatus Renal cancer:8.68e-6 (favourable), Colorectal cancer:3.31e-5 (unfavourable), Glioma:1.25e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 258.6 Expressed in all +SOX8 ENSG00000005513 SRY-box 8 16 981808-986979 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041640, HPA058665 Enhanced Supported Nucleus Tissue enriched Tissue enriched 29 cerebral cortex: 109.9 salivary gland: 3.8 Cell line enriched 5 RH-30: 112.8 +IBTK BTBD26, BTKI, DKFZP564B116 ENSG00000005700 Inhibitor of Bruton tyrosine kinase 6 82169983-82247754 Predicted intracellular proteins Evidence at protein level HPA023826, HPA048438 Uncertain Supported Nucleoplasm Cervical cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 21.4 Expressed in all +ZNF195 ENSG00000005801 Zinc finger protein 195 11 3339261-3379222 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030605 Uncertain Approved Nucleus
Cytosol Urothelial cancer:4.79e-7 (favourable), Liver cancer:3.53e-5 (unfavourable), Renal cancer:7.89e-5 (unfavourable), Prostate cancer:4.24e-4 (unfavourable) Expressed in all Expressed in all epididymis: 21.3 Expressed in all +MYCBP2 FLJ10106, KIAA0916, PAM ENSG00000005810 MYC binding protein 2, E3 ubiquitin protein ligase 13 77044655-77327050 Enzymes, Predicted intracellular proteins Evidence at protein level HPA058807 Supported Nucleus
Vesicles Renal cancer:5.01e-5 (favourable) Expressed in all Expressed in all skin: 82.7 Expressed in all +FBXL3 FBL3, FBL3A, FBXL3A ENSG00000005812 F-box and leucine rich repeat protein 3 13 76992598-77027195 Predicted intracellular proteins Evidence at protein level HPA053283, HPA065626 Enhanced Nuclear bodies Expressed in all Expressed in all thyroid gland: 80.8 Expressed in all +ITGAL CD11A, LFA-1 ENSG00000005844 Integrin subunit alpha L 16 30472658-30523185 CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025011 Enhanced Renal cancer:2.69e-5 (unfavourable), Endometrial cancer:5.63e-5 (favourable), Head and neck cancer:3.34e-4 (favourable), Melanoma:5.57e-4 (favourable) Expressed in all Tissue enhanced lymph node: 79.0;spleen: 80.9 appendix: 52.5 Cell line enriched 5 HMC-1: 570.1 +PDK2 PDHK2 ENSG00000005882 Pyruvate dehydrogenase kinase 2 17 50094737-50112152 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008287 Supported Supported Nucleoplasm
Mitochondria Renal cancer:9.59e-5 (favourable), Cervical cancer:5.87e-4 (favourable) Expressed in all Expressed in all epididymis: 151.5 Mixed +ITGA3 CD49c, GAP-B3, MSK18, VCA-2, VLA3a ENSG00000005884 Integrin subunit alpha 3 17 50055968-50090481 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008572, CAB018594 Enhanced Supported Plasma membrane Pancreatic cancer:5.95e-5 (unfavourable), Head and neck cancer:1.36e-4 (unfavourable), Cervical cancer:6.75e-4 (unfavourable) Expressed in all Mixed lung: 99.0 Cell line enhanced U-87 MG: 917.0 +ZFX ZNF926 ENSG00000005889 Zinc finger protein, X-linked X 24149173-24216255 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001748, HPA003877, HPA071863 Supported Approved Nucleoplasm
Nucleoli Expressed in all Expressed in all parathyroid gland: 33.2 Expressed in all +LAMP2 CD107b ENSG00000005893 Lysosomal associated membrane protein 2 X 120427827-120469365 CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB005272, HPA029100 Enhanced Expressed in all Expressed in all gallbladder: 223.2 Expressed in all +ITGA2B CD41, CD41B, GP2B, PPP1R93 ENSG00000005961 Integrin subunit alpha 2b 17 44372180-44389505 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB018611, HPA031168, HPA031169, HPA031170, HPA031171 Enhanced Mixed Tissue enhanced bone marrow: 11.2;epididymis: 29.3 testis: 4.4 Group enriched 18 HEL: 396.8;HMC-1: 636.9 +ASB4 ASB-4 ENSG00000005981 Ankyrin repeat and SOCS box containing 4 7 95478444-95540232 Predicted intracellular proteins Evidence at transcript level HPA055240 Uncertain Tissue enhanced Group enriched 11 adrenal gland: 50.2;skeletal muscle: 11.5 placenta: 2.8 Cell line enhanced A549: 4.1;Hep G2: 5.2;SCLC-21H: 5.4 +GDE1 MIR16 ENSG00000006007 Glycerophosphodiester phosphodiesterase 1 16 19501689-19522145 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA074747 Approved Nucleus
Nucleoli
Vesicles Renal cancer:3.12e-5 (favourable), Liver cancer:7.52e-5 (unfavourable), Colorectal cancer:3.12e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 67.9 Expressed in all +C19orf60 FLJ20850, FLJ30108, FLJ34606, FLJ37391 ENSG00000006015 Chromosome 19 open reading frame 60 19 18588685-18592336 Predicted intracellular proteins Evidence at protein level HPA043414 Approved Approved Vesicles Urothelial cancer:8.47e-4 (favourable) Expressed in all Mixed skeletal muscle: 22.2 Cell line enhanced PC-3: 78.2 +CRLF1 CISS, CISS1, CLF, CLF-1 ENSG00000006016 Cytokine receptor like factor 1 19 18572220-18607741 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041493, HPA041793 Approved Renal cancer:3.96e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 17.2;placenta: 16.8 adipose tissue: 10.1 Group enriched 8 ASC diff: 706.3;Hep G2: 309.6 +OSBPL7 MGC71150, ORP7 ENSG00000006025 Oxysterol binding protein like 7 17 47807372-47821834 Predicted intracellular proteins Evidence at protein level HPA036076, HPA053083 Uncertain Approved Nucleoplasm
Cytosol Urothelial cancer:1.19e-5 (favourable), Renal cancer:8.30e-4 (unfavourable) Expressed in all Mixed stomach: 33.1 Cell line enhanced HaCaT: 38.6 +TMEM98 DKFZP564K1964 ENSG00000006042 Transmembrane protein 98 17 32927910-32945106 Disease related genes, Predicted membrane proteins Evidence at protein level HPA040473, HPA053385 Uncertain Supported Nucleoplasm Renal cancer:3.85e-4 (favourable), Lung cancer:7.10e-4 (favourable), Liver cancer:8.14e-4 (unfavourable) Expressed in all Expressed in all ovary: 238.1 Mixed +YBX2 Contrin, CSDA3, MSY2 ENSG00000006047 Y-box binding protein 2 17 7288252-7294615 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB012332, HPA053904, HPA056744 Enhanced Supported Nucleoli fibrillar center Endometrial cancer:6.50e-5 (unfavourable) Mixed Tissue enriched 64 testis: 385.4 adipose tissue: 6.0 Cell line enhanced CACO-2: 8.7;MCF7: 14.2;T-47d: 25.9 +KRT33A Ha-3I, Krt1-3, KRTHA3A ENSG00000006059 Keratin 33A 17 41346092-41350812 Predicted intracellular proteins Evidence at protein level HPA055194 Supported Tissue enhanced Group enriched 15 esophagus: 1.4;testis: 1.6 all non-specific tissues: 0.0 Cell line enhanced RT4: 1.1 +MAP3K14 FTDCR1B, HS, HSNIK, NIK ENSG00000006062 Mitogen-activated protein kinase kinase kinase 14 17 45263121-45317040 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027269, HPA027270 Approved Supported Nucleus
Nucleoli fibrillar center
Vesicles
Cytosol Cervical cancer:5.27e-5 (favourable), Renal cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all lymph node: 22.8 Mixed +ABCC8 ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2 ENSG00000006071 ATP binding cassette subfamily C member 8 11 17392885-17476845 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB011451, HPA042318 Approved Approved Nucleoli
Golgi apparatus
Cytosol Tissue enriched Tissue enhanced cerebral cortex: 11.3 adrenal gland: 7.5 Cell line enhanced A549: 1.7;AN3-CA: 1.8;SCLC-21H: 9.0 +CACNG3 ENSG00000006116 Calcium voltage-gated channel auxiliary subunit gamma 3 16 24255553-24362801 Predicted membrane proteins, Transporters Evidence at protein level HPA059010 Approved Tissue enriched Tissue enriched 28 cerebral cortex: 42.5 adrenal gland: 1.5 Not detected +TMEM132A FLJ20539, GBP, HSPA5BP1 ENSG00000006118 Transmembrane protein 132A 11 60924463-60937159 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051979, HPA060492 Enhanced Approved Mitochondria Renal cancer:1.55e-9 (unfavourable), Endometrial cancer:1.98e-5 (favourable) Expressed in all Tissue enhanced cerebral cortex: 94.2 placenta: 25.0 Cell line enhanced EFO-21: 167.6 +AP2B1 ADTB2, CLAPB1 ENSG00000006125 Adaptor related protein complex 2 beta 1 subunit 17 35578046-35726409 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB017631, HPA056733, HPA067983 Approved Supported Vesicles Renal cancer:2.62e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 265.4 Expressed in all +TAC1 NKNA, NPK, TAC2 ENSG00000006128 Tachykinin precursor 1 7 97731908-97740472 Predicted secreted proteins Evidence at protein level CAB004588, HPA014429 Approved Mixed Tissue enhanced cerebral cortex: 77.7;spleen: 47.0 appendix: 13.2 Cell line enriched 14 U-266/70: 16.5 +ZNF263 FPM315, ZKSCAN12, ZSCAN44 ENSG00000006194 Zinc finger protein 263 16 3263800-3301401 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035085, HPA035086 Approved Supported Nucleoplasm
Mitotic spindle
Cytosol Expressed in all Expressed in all parathyroid gland: 58.2 Expressed in all +CX3CL1 ABCD-3, C3Xkine, CXC3, CXC3C, fractalkine, neurotactin, NTN, SCYD1 ENSG00000006210 C-X3-C motif chemokine ligand 1 16 57372458-57385048 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB026192, HPA040361 Approved Supported Plasma membrane Renal cancer:8.52e-7 (favourable), Cervical cancer:9.46e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 100.1 lung: 69.3 Cell line enhanced EFO-21: 28.0;HDLM-2: 78.9;Hep G2: 42.9;RPTEC TERT1: 27.3 +SPATA20 FLJ21347, SSP411, Tisp78 ENSG00000006282 Spermatogenesis associated 20 17 50543058-50555852 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA022023, HPA027144, HPA031442 Enhanced Approved Nucleoplasm Urothelial cancer:9.69e-5 (favourable) Expressed in all Expressed in all testis: 97.7 Mixed +CACNA1G Cav3.1, NBR13 ENSG00000006283 Calcium voltage-gated channel subunit alpha1 G 17 50561068-50627474 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA004714 Uncertain Mixed Tissue enhanced cerebral cortex: 10.5;cervix, uterine: 8.5 endometrium: 5.2 Cell line enhanced A549: 8.5;SCLC-21H: 3.3 +TNFRSF12A CD266, FN14, TweakR ENSG00000006327 TNF receptor superfamily member 12A 16 3018445-3022383 Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007853 Approved Approved Plasma membrane
Cytosol Head and neck cancer:5.50e-4 (unfavourable), Renal cancer:8.78e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 199.0 Mixed +DLX6 ENSG00000006377 Distal-less homeobox 6 7 97005548-97011039 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA030608, HPA061460 Uncertain Approved Nuclear bodies Tissue enriched Tissue enhanced endometrium: 4.4;placenta: 4.3;testis: 5.4 cervix, uterine: 3.0 Cell line enhanced AN3-CA: 9.4;BEWO: 32.1;HAP1: 15.7;SCLC-21H: 8.6;SH-SY5Y: 11.6 +MAP3K9 MEKK9, MLK1, PRKE1 ENSG00000006432 Mitogen-activated protein kinase kinase kinase 9 14 70722526-70809534 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000942 Approved Approved Nucleus
Nucleoli Mixed Mixed testis: 10.1 Cell line enhanced A-431: 20.2 +RALA RAL ENSG00000006451 RAS like proto-oncogene A 7 39623483-39708124 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA065232 Approved Liver cancer:5.32e-5 (unfavourable), Pancreatic cancer:6.30e-4 (unfavourable), Ovarian cancer:7.46e-4 (favourable) Expressed in all Expressed in all lung: 60.3 Expressed in all +BAIAP2L1 IRTKS ENSG00000006453 BAI1 associated protein 2 like 1 7 98291651-98401068 Predicted intracellular proteins Evidence at protein level HPA019484, HPA021257, HPA023874, HPA029503 Enhanced Enhanced Plasma membrane
Cytosol Mixed Mixed stomach: 55.2 Mixed +KDM7A JHDM1D, KIAA1718 ENSG00000006459 Lysine demethylase 7A 7 140084746-140177035 Predicted secreted proteins Evidence at protein level HPA012114 Uncertain Approved Nucleoplasm
Nucleoli Expressed in all Mixed cervix, uterine: 14.2 Mixed +ETV1 ER81 ENSG00000006468 ETS variant 1 7 13891228-13991425 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA077249 Approved Nucleoplasm Expressed in all Tissue enhanced cerebral cortex: 106.3 lung: 43.1 Cell line enhanced SCLC-21H: 93.4;U-87 MG: 152.1;WM-115: 77.6 +AGK FLJ10842, MULK ENSG00000006530 Acylglycerol kinase 7 141551189-141655244 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020959, HPA053471 Supported Supported Vesicles
Mitochondria Expressed in all Expressed in all parathyroid gland: 26.9 Expressed in all +ALDH3B1 ALDH7 ENSG00000006534 Aldehyde dehydrogenase 3 family member B1 11 68008578-68029282 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038525 Uncertain Colorectal cancer:1.18e-4 (unfavourable), Pancreatic cancer:6.07e-4 (unfavourable) Expressed in all Tissue enhanced fallopian tube: 64.4;lung: 67.7 bone marrow: 30.7 Cell line enhanced A549: 137.9;CAPAN-2: 136.9 +TTC22 FLJ20619 ENSG00000006555 Tetratricopeptide repeat domain 22 1 54779712-54801267 Predicted intracellular proteins Evidence at protein level HPA035072 Uncertain Breast cancer:2.06e-4 (favourable), Liver cancer:7.73e-4 (unfavourable) Mixed Tissue enhanced esophagus: 40.6 skin: 22.7 Cell line enhanced A-431: 7.9;CAPAN-2: 9.5;HaCaT: 11.0;hTCEpi: 5.0;RPMI-8226: 5.6 +PHTF2 DKFZp434D166 ENSG00000006576 Putative homeodomain transcription factor 2 7 77798792-77957503 Predicted membrane proteins, Transcription factors Evidence at protein level HPA012312 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.09e-7 (unfavourable), Thyroid cancer:2.78e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 62.0 Expressed in all +CCL26 eotaxin-3, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1 ENSG00000006606 C-C motif chemokine ligand 26 7 75769533-75789896 Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced ovary: 12.0 rectum: 7.6 Cell line enhanced hTEC/SVTERT24-B: 15.8;PC-3: 42.0;U-2 OS: 13.1 +FARP2 FIR, FRG, KIAA0793, PLEKHC3 ENSG00000006607 FERM, ARH/RhoGEF and pleckstrin domain protein 2 2 241356243-241494841 Predicted intracellular proteins Evidence at protein level HPA031226, HPA055592 Approved Approved Cytosol Expressed in all Expressed in all testis: 37.9 Expressed in all +USH1C AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C ENSG00000006611 USH1 protein network component harmonin 11 17493895-17544416 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB013690, HPA027398, HPA027492, HPA028033 Supported Enhanced Cytosol Liver cancer:2.20e-4 (unfavourable), Renal cancer:9.41e-4 (favourable) Group enriched Tissue enhanced duodenum: 99.2;small intestine: 106.9 kidney: 55.4 Cell line enhanced CACO-2: 50.5;CAPAN-2: 7.4;HeLa: 14.4 +GGCT C7orf24, CRF21, GCTG, Ggc, MGC3077 ENSG00000006625 Gamma-glutamylcyclotransferase 7 30496621-30504844 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020735, HPA029914 Approved Liver cancer:7.23e-4 (unfavourable), Breast cancer:7.68e-4 (unfavourable) Expressed in all Expressed in all epididymis: 125.5 Expressed in all +DBF4 ASK, chif, DBF4A, ZDBF1 ENSG00000006634 DBF4 zinc finger 7 87876216-87909541 Predicted intracellular proteins Evidence at protein level HPA042923 Approved Nucleus
Nuclear bodies Renal cancer:6.42e-7 (unfavourable), Liver cancer:4.45e-6 (unfavourable), Melanoma:6.86e-4 (unfavourable) Expressed in all Tissue enriched 41 testis: 21.4 gallbladder: 0.5 Mixed +TBXA2R ENSG00000006638 Thromboxane A2 receptor 19 3594506-3606840 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA077366 Supported Nuclear speckles
Plasma membrane Renal cancer:1.45e-4 (unfavourable), Pancreatic cancer:7.17e-4 (favourable) Expressed in all Mixed spleen: 5.2 Cell line enhanced HeLa: 6.4;U-2197: 6.3 +IFRD1 PC4, TIS7 ENSG00000006652 Interferon related developmental regulator 1 7 112422968-112481017 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024122 Approved Approved Plasma membrane
Cytosol Ovarian cancer:5.45e-4 (favourable) Expressed in all Expressed in all bone marrow: 129.9 Expressed in all +LGALS14 CLC2, PPL13 ENSG00000006659 Galectin 14 19 39704306-39709444 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 57 placenta: 69.0 skin: 1.2 Cell line enhanced EFO-21: 3.0;U-266/70: 5.8 +COX10 ENSG00000006695 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 17 14069496-14208677 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA032005, HPA032006 Supported Supported Nucleoli
Mitochondria
Cytosol Renal cancer:4.32e-6 (favourable), Stomach cancer:8.73e-4 (favourable) Expressed in all Expressed in all testis: 43.1 Expressed in all +GTF2IRD1 BEN, Cream1, GTF3, MusTRD1, RBAP2, WBSCR11, WBSCR12 ENSG00000006704 GTF2I repeat domain containing 1 7 74453790-74602604 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044254 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:9.71e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 34.9 Mixed +PAF1 F23149_1, FLJ11123, PD2 ENSG00000006712 PAF1 homolog, Paf1/RNA polymerase II complex component 19 39385852-39391195 Predicted intracellular proteins Evidence at protein level HPA041875, HPA043637 Approved Supported Nucleoplasm Pancreatic cancer:8.66e-4 (favourable), Liver cancer:8.68e-4 (unfavourable) Expressed in all Expressed in all testis: 87.1 Expressed in all +VPS41 HVSP41 ENSG00000006715 VPS41, HOPS complex subunit 7 38722963-38932394 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020080, HPA020299 Approved Renal cancer:3.40e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 96.8 Expressed in all +ARHGAP44 KIAA0672, RICH-2, RICH2 ENSG00000006740 Rho GTPase activating protein 44 17 12789539-12991643 Predicted intracellular proteins Evidence at protein level HPA038814 Uncertain Mixed Tissue enhanced parathyroid gland: 51.6 cerebral cortex: 33.4 Cell line enhanced HEK 293: 9.0 +ELAC2 FLJ10530, HPC2 ENSG00000006744 ElaC ribonuclease Z 2 17 12992391-13018187 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019535 Approved Enhanced Nucleoplasm Endometrial cancer:3.24e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 55.1 Expressed in all +SCIN KIAA1905 ENSG00000006747 Scinderin 7 12570577-12660179 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020518, HPA024264 Enhanced Enhanced Plasma membrane Renal cancer:4.26e-8 (favourable) Tissue enhanced Tissue enhanced placenta: 110.4 kidney: 52.0 Cell line enhanced RPTEC TERT1: 71.2;SK-BR-3: 76.9 +ARSD ENSG00000006756 Arylsulfatase D X 2903970-2929351 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004694, HPA063835 Approved Approved Vesicles
Lipid droplets Renal cancer:1.97e-5 (favourable), Endometrial cancer:5.21e-4 (favourable) Expressed in all Mixed fallopian tube: 45.3 Cell line enhanced EFO-21: 23.1 +PNPLA4 DXS1283E, GS2, iPLA2eta ENSG00000006757 Patatin like phospholipase domain containing 4 X 7898247-7927739 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003656 Approved Renal cancer:2.23e-12 (favourable), Glioma:4.67e-4 (unfavourable), Head and neck cancer:5.37e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 50.2 Mixed +MYH13 MyHC-eo ENSG00000006788 Myosin heavy chain 13 17 10300865-10373130 Plasma proteins, Predicted intracellular proteins Evidence at protein level Not detected Not detected placenta: 0.7 Cell line enhanced U-2 OS: 3.1 +ADIPOR2 ACDCR2, PAQR2 ENSG00000006831 Adiponectin receptor 2 12 1688574-1788678 Predicted membrane proteins Evidence at protein level HPA043737 Approved Expressed in all Expressed in all adipose tissue: 77.1 Expressed in all +CDKL3 NKIAMRE ENSG00000006837 Cyclin dependent kinase like 3 5 134286350-134371047 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027751 Uncertain Nucleoplasm
Vesicles Mixed Tissue enriched 9 testis: 28.9 cerebral cortex: 3.2 Mixed +UPP2 UDRPASE2, UP2, UPASE2 ENSG00000007001 Uridine phosphorylase 2 2 157876702-158136154 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035225, HPA035226 Approved Nucleus
Vesicles
Mitochondria Tissue enriched Group enriched 14 kidney: 52.2;liver: 14.3 cerebral cortex: 2.4 Not detected +PRSS21 ESP-1, TEST1 ENSG00000007038 Protease, serine 21 16 2817180-2826304 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008477 Enhanced Approved Cytosol Tissue enhanced Tissue enriched 10 testis: 49.5 bone marrow: 4.7 Cell line enhanced CAPAN-2: 22.0;HEL: 25.5;HeLa: 48.0;K-562: 30.5;U-698: 70.6 +MARK4 FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D ENSG00000007047 Microtubule affinity regulating kinase 4 19 45079288-45305283 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039186 Approved Approved Cytosol Endometrial cancer:8.31e-8 (unfavourable), Head and neck cancer:3.05e-5 (unfavourable) Expressed in all Expressed in all testis: 51.2 Expressed in all +PROM1 AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4 ENSG00000007062 Prominin 1 4 15963076-16084378 CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004922, CAB011525, HPA031053 Enhanced Renal cancer:2.56e-5 (favourable) Expressed in all Tissue enhanced cervix, uterine: 67.2 gallbladder: 47.5 Cell line enhanced AF22: 36.7;CACO-2: 58.5;EFO-21: 62.9;NTERA-2: 99.9;RPTEC TERT1: 69.7 +CCDC124 ENSG00000007080 Coiled-coil domain containing 124 19 17933016-17943991 Predicted intracellular proteins Evidence at protein level HPA041708, HPA046765 Supported Enhanced Plasma membrane
Cytosol Liver cancer:1.68e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 72.4 Expressed in all +CEACAM21 FLJ13540, R29124_1 ENSG00000007129 Carcinoembryonic antigen related cell adhesion molecule 21 19 41549518-41586844 Predicted membrane proteins Evidence at transcript level HPA043411 Uncertain Endometrial cancer:1.89e-5 (favourable) Mixed Tissue enhanced bone marrow: 11.0 spleen: 6.5 Cell line enhanced HMC-1: 6.0;Karpas-707: 3.9;U-266/70: 4.6;U-937: 3.7 +PAFAH1B1 LIS1, MDCR, MDS, NudF, PAFAH ENSG00000007168 Platelet activating factor acetylhydrolase 1b regulatory subunit 1 17 2593210-2685615 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004489, HPA020036 Approved Enhanced Centrosome Renal cancer:3.16e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 178.7 Expressed in all +NOS2 HEP-NOS, iNOS, NOS, NOS2A ENSG00000007171 Nitric oxide synthase 2 17 27756766-27800499 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002014 Approved Tissue enhanced Group enriched 5 appendix: 18.9;colon: 7.0;duodenum: 12.3;rectum: 9.8;small intestine: 24.1;urinary bladder: 6.5 smooth muscle: 2.5 Group enriched 8 CACO-2: 13.0;SCLC-21H: 14.7 +DNAH9 DNAH17L, Dnahc9, DNAL1, DYH9, HL-20, HL20, KIAA0357 ENSG00000007174 Dynein axonemal heavy chain 9 17 11598431-11969748 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052641 Enhanced Endometrial cancer:6.79e-5 (favourable) Tissue enhanced Tissue enriched 5 fallopian tube: 56.4 testis: 11.1 Cell line enhanced HDLM-2: 2.8;WM-115: 1.7 +KIAA0100 BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, MGC111488 ENSG00000007202 KIAA0100 17 28614440-28645454 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042781 Uncertain Approved Nuclear speckles
Cytosol Liver cancer:3.47e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 92.4 Expressed in all +SLC13A2 NaDC-1 ENSG00000007216 Solute carrier family 13 member 2 17 28473293-28497781 Predicted membrane proteins, Transporters Evidence at protein level HPA014963 Enhanced Renal cancer:9.00e-4 (favourable) Mixed Tissue enhanced duodenum: 68.7;small intestine: 54.3 kidney: 19.7 Not detected +GAS7 KIAA0394, MGC1348 ENSG00000007237 Growth arrest specific 7 17 9910609-10198551 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA004838, HPA064678 Enhanced Approved Plasma membrane
Actin filaments
Focal adhesion sites Urothelial cancer:6.89e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 154.7 cervix, uterine: 47.6 Cell line enriched 11 WM-115: 526.3 +TRAPPC6A HSPC289, MGC2650, TRS33 ENSG00000007255 Trafficking protein particle complex 6A 19 45162928-45178237 Predicted intracellular proteins Evidence at protein level HPA043043 Approved Renal cancer:2.23e-6 (favourable) Expressed in all Expressed in all thyroid gland: 47.5 Expressed in all +MATK CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101 ENSG00000007264 Megakaryocyte-associated tyrosine kinase 19 3777970-3802129 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA004847 Approved Breast cancer:5.27e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 22.0 spleen: 19.8 Cell line enhanced HL-60: 85.8;K-562: 43.3;NB-4: 47.4;SCLC-21H: 36.7 +CEACAM7 CEA, CGM2 ENSG00000007306 Carcinoembryonic antigen related cell adhesion molecule 7 19 41673307-41706976 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA069621 Supported Tissue enhanced Group enriched 7 colon: 583.2;rectum: 691.9 appendix: 91.6 Not detected +CD79B B29, IGB ENSG00000007312 CD79b molecule 17 63928740-63932354 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level HPA009178, CAB009751 Enhanced Uncertain Nucleoplasm
Plasma membrane
Cytosol Head and neck cancer:2.35e-4 (favourable) Expressed in all Group enriched 5 appendix: 91.1;lymph node: 311.5;spleen: 157.4;tonsil: 189.1 bone marrow: 36.1 Group enriched 17 Daudi: 751.6;REH: 317.0;U-698: 986.5 +SCN4A HYKPP, HYPP, Nav1.4, SkM1 ENSG00000007314 Sodium voltage-gated channel alpha subunit 4 17 63938554-63972918 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA053992 Approved Nucleoplasm
Microtubule organizing center Tissue enhanced Group enriched 9 adipose tissue: 12.4;skeletal muscle: 47.2 thyroid gland: 3.3 Group enriched 13 REH: 13.6;RH-30: 43.5 +ST7L FAM4B, FLJ20284, ST7R, STLR ENSG00000007341 Suppression of tumorigenicity 7 like 1 112523518-112620825 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA042324, HPA075418 Uncertain Approved Centrosome Ovarian cancer:3.04e-5 (favourable), Colorectal cancer:8.34e-5 (favourable), Melanoma:5.16e-4 (unfavourable), Endometrial cancer:8.96e-4 (unfavourable) Expressed in all Tissue enriched 5 testis: 65.0 thyroid gland: 12.4 Mixed +TKTL1 TKR, TKT2 ENSG00000007350 Transketolase like 1 X 154295671-154330350 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000505, CAB032191 Enhanced Tissue enriched Tissue enriched 141 testis: 225.8 heart muscle,lung: 1.5 Cell line enriched 147 THP-1: 315.9 +PAX6 AN, AN2, D11S812E, WAGR ENSG00000007372 Paired box 6 11 31784779-31818062 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA030775, CAB034143 Supported Enhanced Nucleoplasm Tissue enhanced Group enriched 7 cerebral cortex: 22.3;stomach: 11.2 testis: 2.5 Cell line enhanced AF22: 15.6;AN3-CA: 19.1;HEK 293: 17.3;U-251 MG: 14.4 +RPUSD1 C16orf40, MGC19600, RLUCL ENSG00000007376 RNA pseudouridylate synthase domain containing 1 16 784974-788397 Predicted intracellular proteins Evidence at protein level HPA041144, HPA041938 Approved Approved Nucleus
Golgi apparatus
Cell Junctions
Cytosol Expressed in all Expressed in all appendix: 13.0 Expressed in all +RHBDF1 C16orf8, Dist1, EGFR-RS, FLJ2235, iRhom1 ENSG00000007384 Rhomboid 5 homolog 1 16 58059-76355 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA077399 Uncertain Vesicles Renal cancer:2.49e-5 (unfavourable) Expressed in all Mixed placenta: 39.8 Mixed +LUC7L hLuc7B1, Luc7, LUC7B1 ENSG00000007392 LUC7 like 16 188969-229463 Predicted intracellular proteins Evidence at protein level HPA056424, HPA069321 Supported Approved Nucleus
Mitochondria Pancreatic cancer:1.30e-4 (favourable), Renal cancer:2.59e-4 (unfavourable) Expressed in all Expressed in all testis: 41.4 Expressed in all +CACNA2D2 KIAA0558 ENSG00000007402 Calcium voltage-gated channel auxiliary subunit alpha2delta 2 3 50362799-50504244 FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA034771, HPA071829 Enhanced Approved Vesicles Endometrial cancer:7.62e-5 (unfavourable), Pancreatic cancer:1.21e-4 (favourable) Tissue enhanced Tissue enriched 6 lung: 72.9 testis: 12.4 Cell line enriched 8 SH-SY5Y: 201.7 +BAIAP3 BAP3, KIAA0734 ENSG00000007516 BAI1 associated protein 3 16 1333601-1349441 Predicted intracellular proteins Evidence at protein level HPA015627 Uncertain Renal cancer:1.52e-5 (favourable) Mixed Tissue enhanced adrenal gland: 24.9;cerebral cortex: 25.1;fallopian tube: 42.4 testis: 13.8 Cell line enhanced CAPAN-2: 17.3 +TSR3 C16orf42, MGC24381 ENSG00000007520 TSR3, acp transferase ribosome maturation factor 16 1349240-1351911 Predicted intracellular proteins Evidence at protein level HPA040760, HPA046265 Uncertain Approved Golgi apparatus
Cytosol Expressed in all Expressed in all cerebral cortex: 36.7 Expressed in all +PIGQ GPI1, hGPI1 ENSG00000007541 Phosphatidylinositol glycan anchor biosynthesis class Q 16 566995-584136 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039105, HPA039828, HPA061414 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:2.53e-6 (favourable) Expressed in all Expressed in all bone marrow: 17.5 Expressed in all +CRAMP1 CRAMP1L, KIAA1426 ENSG00000007545 Cramped chromatin regulator homolog 1 16 1612325-1677908 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041752 Uncertain Approved Nucleus
Nucleoli
Cytosol Stomach cancer:4.93e-4 (favourable) Expressed in all Mixed testis: 31.8 Expressed in all +TEAD3 ETFR-1, TEAD5, TEF-5 ENSG00000007866 TEA domain transcription factor 3 6 35473597-35497076 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028906 Uncertain Renal cancer:1.01e-7 (unfavourable), Endometrial cancer:5.09e-4 (unfavourable) Expressed in all Mixed smooth muscle: 80.5 Cell line enhanced BEWO: 114.2 +SELE CD62E, ELAM, ELAM1, ESEL ENSG00000007908 Selectin E 1 169722641-169764705 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002143 Enhanced Mixed Tissue enhanced parathyroid gland: 45.2;prostate: 46.4 urinary bladder: 27.8 Cell line enriched 6 HUVEC TERT2: 1.0 +DNAJC11 FLJ10737 ENSG00000007923 DnaJ heat shock protein family (Hsp40) member C11 1 6634168-6701924 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028705 Uncertain Approved Cytosol Renal cancer:2.63e-5 (favourable) Expressed in all Expressed in all kidney: 38.4 Expressed in all +FMO3 ENSG00000007933 Flavin containing monooxygenase 3 1 171090877-171117819 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013750 Enhanced Lung cancer:5.60e-5 (favourable), Renal cancer:1.13e-4 (unfavourable), Liver cancer:3.46e-4 (favourable) Tissue enriched Tissue enriched 24 liver: 556.7 fallopian tube: 22.8 Group enriched 13 ASC diff: 23.4;ASC TERT1: 17.9;HSkMC: 5.1 +MYLIP IDOL, MIR ENSG00000007944 Myosin regulatory light chain interacting protein 6 16129125-16148248 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Lung cancer:6.44e-6 (favourable), Urothelial cancer:4.11e-5 (favourable), Renal cancer:3.67e-4 (favourable) Expressed in all Expressed in all placenta: 119.3 Mixed +NOX1 GP91-2, MOX1, NOH-1, NOH1 ENSG00000007952 NADPH oxidase 1 X 100843324-100874345 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Colorectal cancer:9.71e-4 (favourable) Tissue enriched Group enriched 17 colon: 58.7;rectum: 79.9 appendix: 3.9 Cell line enriched 19 CACO-2: 25.5 +E2F2 E2F-2 ENSG00000007968 E2F transcription factor 2 1 23506430-23531220 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB016313 Uncertain Mixed Tissue enhanced bone marrow: 15.3 lymph node: 3.8 Cell line enhanced Daudi: 33.3 +PSMB1 HC5, PMSB1 ENSG00000008018 Proteasome subunit beta 1 6 170535117-170553341 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029635, HPA029637, CAB033911 Enhanced Supported Nucleus Renal cancer:3.76e-6 (unfavourable) Expressed in all Expressed in all epididymis: 320.2 Expressed in all +SYN1 ENSG00000008056 Synapsin I X 47571898-47619943 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000397, CAB021929 Enhanced Tissue enhanced Tissue enriched 26 cerebral cortex: 378.9 adrenal gland: 14.5 Cell line enhanced NTERA-2: 17.4;SCLC-21H: 35.6;SH-SY5Y: 8.3 +JARID2 JMJ ENSG00000008083 Jumonji and AT-rich interaction domain containing 2 6 15246296-15522040 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063889, CAB069890 Uncertain Supported Nucleus
Mitochondria Expressed in all Mixed bone marrow: 36.5 Expressed in all +CDKL5 CFAP247, EIEE2, STK9 ENSG00000008086 Cyclin dependent kinase like 5 X 18425583-18653629 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002847, CAB011577 Supported Enhanced Nucleoplasm Renal cancer:5.54e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 31.0 testis: 14.4 Mixed +CAMK1G CLICKIII, dJ272L16.1, VWS1 ENSG00000008118 Calcium/calmodulin dependent protein kinase IG 1 209583717-209613938 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 32.3;ovary: 27.7 seminal vesicle: 7.4 Cell line enhanced hTEC/SVTERT24-B: 7.0;SK-MEL-30: 1.6 +CDK11A CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE ENSG00000008128 Cyclin dependent kinase 11A 1 1702730-1724324 Enzymes, Predicted intracellular proteins Evidence at protein level CAB010467, HPA025061, HPA073626 Enhanced Supported Nuclear speckles
Cytosol Renal cancer:1.15e-6 (unfavourable), Melanoma:5.06e-4 (unfavourable) Expressed in all Expressed in all small intestine: 35.1 Expressed in all +NADK FLJ13052 ENSG00000008130 NAD kinase 1 1751232-1780457 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048909, HPA053368 Uncertain Approved Nucleoplasm
Vesicles Expressed in all Expressed in all spleen: 77.4 Expressed in all +TFAP2B AP2-B ENSG00000008196 Transcription factor AP-2 beta 6 50818723-50847613 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034683, HPA062942 Supported Approved Nucleoplasm Tissue enriched Tissue enhanced epididymis: 39.4 breast: 9.6 Group enriched 5 AF22: 94.8;SH-SY5Y: 188.6 +TFAP2D TFAP2BL1 ENSG00000008197 Transcription factor AP-2 delta 6 50713828-50772988 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048962 Uncertain Tissue enriched Not detected cerebral cortex: 0.1 Cell line enhanced HAP1: 1.3 +DLEC1 CFAP81, DLC1 ENSG00000008226 Deleted in lung and esophageal cancer 1 3 38039205-38124025 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019077 Enhanced Supported Cytosol Mixed Tissue enhanced fallopian tube: 29.7;testis: 17.3 lung: 5.9 Not detected +CYTH3 ARNO3, cytohesin-3, GRP1, PSCD3 ENSG00000008256 Cytohesin 3 7 6161776-6272644 Predicted intracellular proteins Evidence at protein level HPA013979 Uncertain Supported Nucleoplasm
Cytosol Urothelial cancer:2.63e-5 (unfavourable) Expressed in all Expressed in all placenta: 45.5 Mixed +ADAM22 MDC2 ENSG00000008277 ADAM metallopeptidase domain 22 7 87934143-88202889 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA050325 Approved Cell Junctions Mixed Tissue enhanced cerebral cortex: 47.6 prostate: 18.2 Cell line enhanced Karpas-707: 58.7;SH-SY5Y: 81.7 +SYPL1 SYPL ENSG00000008282 Synaptophysin like 1 7 106090503-106112576 Predicted membrane proteins Evidence at protein level HPA014141 Approved Renal cancer:1.25e-9 (favourable) Expressed in all Expressed in all thyroid gland: 194.9 Mixed +CYB561 CYB561A1, FRRS2 ENSG00000008283 Cytochrome b561 17 63432304-63446378 Predicted membrane proteins, Transporters Evidence at protein level HPA014753 Approved Endometrial cancer:2.95e-5 (favourable), Breast cancer:8.89e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 163.4 Cell line enhanced SH-SY5Y: 448.0 +SPAG9 CT89, FLJ13450, FLJ14006, FLJ26141, FLJ34602, HLC4, HSS, JIP-4, JIP4, JLP, KIAA0516, MGC117291, MGC14967, MGC74461, PHET, PIG6, SYD1 ENSG00000008294 Sperm associated antigen 9 17 50962174-51120865 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040446, HPA061458 Approved Enhanced Microtubule organizing center
Cytosol Urothelial cancer:8.10e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 106.2 Expressed in all +CELSR3 ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2 ENSG00000008300 Cadherin EGF LAG seven-pass G-type receptor 3 3 48636469-48662915 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA062866 Approved Mixed Group enriched 6 adrenal gland: 1.6;cerebral cortex: 5.9;testis: 3.5 parathyroid gland,stomach: 0.6 Cell line enhanced SH-SY5Y: 19.4;SiHa: 17.5 +AASS LKRSDH, LORSDH ENSG00000008311 Aminoadipate-semialdehyde synthase 7 122075647-122144280 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020637, HPA020728, HPA020734 Enhanced Enhanced Vesicles
Mitochondria Liver cancer:9.81e-4 (favourable) Expressed in all Mixed ovary: 30.7 Cell line enhanced AN3-CA: 49.4;NTERA-2: 51.8 +PLEKHG6 FLJ10665, MYOGEF ENSG00000008323 Pleckstrin homology and RhoGEF domain containing G6 12 6310436-6328506 Predicted intracellular proteins Evidence at protein level HPA041459, HPA058230 Uncertain Supported Cell Junctions
Centrosome Mixed Tissue enhanced small intestine: 47.7 duodenum: 36.5 Cell line enhanced BEWO: 147.7;CACO-2: 41.4;RT4: 42.4 +SS18L2 KIAA-iso ENSG00000008324 SS18 like 2 3 42581840-42595114 Predicted intracellular proteins Evidence at protein level HPA047377 Uncertain Approved Nucleus
Nucleoli
Mitochondria Lung cancer:7.03e-4 (favourable) Expressed in all Expressed in all lymph node: 61.0 Expressed in all +MPND FLJ14981 ENSG00000008382 MPN domain containing 19 4343527-4360086 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043274, HPA045475 Approved Approved Nucleus
Nucleoli Lung cancer:1.55e-4 (favourable), Cervical cancer:2.99e-4 (favourable), Endometrial cancer:6.12e-4 (favourable), Renal cancer:7.04e-4 (favourable) Expressed in all Expressed in all duodenum: 30.9 Expressed in all +MGST1 GST12, MGST-I ENSG00000008394 Microsomal glutathione S-transferase 1 12 16347142-16609259 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044840 Enhanced Approved Endoplasmic reticulum
Mitochondria Thyroid cancer:1.97e-4 (favourable), Renal cancer:7.45e-4 (unfavourable) Expressed in all Expressed in all liver: 1602.4 Cell line enhanced ASC diff: 3718.8 +CRY1 PHLL1 ENSG00000008405 Cryptochrome circadian clock 1 12 106991364-107093829 Predicted intracellular proteins Evidence at protein level CAB018762 Approved Supported Nucleus
Nuclear membrane
Microtubules Expressed in all Expressed in all testis: 62.1 Mixed +PGLYRP1 PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L ENSG00000008438 Peptidoglycan recognition protein 1 19 46019153-46023065 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA045702 Enhanced Not detected Tissue enriched 57 bone marrow: 421.1 spleen: 7.4 Cell line enhanced A549: 2.9 +NFIX NF1A ENSG00000008441 Nuclear factor I X 19 12995608-13098796 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007533 Supported Supported Nucleoplasm Lung cancer:2.35e-4 (favourable), Liver cancer:4.66e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 191.5 Cell line enhanced U-138 MG: 192.9;U-2197: 175.5 +ST3GAL1 SIAT4A, SIATFL, ST3GalA.1, ST3O ENSG00000008513 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 8 133454848-133571940 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040466 Approved Expressed in all Expressed in all thyroid gland: 115.9 Cell line enhanced PC-3: 125.9;RT4: 84.6 +MMP25 MMP20, MMPL1, MT6-MMP ENSG00000008516 Matrix metallopeptidase 25 16 3046681-3060726 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025177 Uncertain Head and neck cancer:1.09e-5 (favourable) Tissue enhanced Tissue enhanced appendix: 23.3;bone marrow: 24.7;spleen: 20.7 adipose tissue: 6.4 Cell line enriched 11 HMC-1: 95.7 +IL32 NK4, TAIF, TAIFb, TAIFd ENSG00000008517 Interleukin 32 16 3065297-3082192 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029397, CAB030029 Approved Endometrial cancer:1.33e-4 (favourable) Expressed in all Expressed in all small intestine: 620.5 Cell line enhanced CACO-2: 405.3;HDLM-2: 655.8;RH-30: 334.4 +PKD1 PBP, Pc-1, TRPP1 ENSG00000008710 Polycystin 1, transient receptor potential channel interacting 16 2088710-2135898 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB046448 Approved Pancreatic cancer:3.38e-5 (favourable), Head and neck cancer:3.35e-4 (favourable), Colorectal cancer:7.43e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 21.6 Expressed in all +MAPK8IP2 IB2, JIP2, PRKM8IPL ENSG00000008735 Mitogen-activated protein kinase 8 interacting protein 2 22 50600685-50613981 Predicted intracellular proteins Evidence at protein level HPA034780 Uncertain Mixed Tissue enriched 8 cerebral cortex: 78.2 adrenal gland: 10.0 Cell line enhanced SCLC-21H: 24.1;SH-SY5Y: 19.6 +MED24 CRSP100, CRSP4, DRIP100, KIAA0130, MED5, THRAP4, TRAP100 ENSG00000008838 Mediator complex subunit 24 17 40019097-40061215 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all testis: 64.3 Expressed in all +RHOBTB2 DBC2, KIAA0717 ENSG00000008853 Rho related BTB domain containing 2 8 22987417-23020199 Predicted intracellular proteins Evidence at protein level HPA060938 Approved Approved Plasma membrane Renal cancer:2.98e-4 (favourable) Expressed in all Mixed lung: 52.7 Expressed in all +HEATR5B DKFZp686P15184, KIAA1414 ENSG00000008869 HEAT repeat containing 5B 2 36968383-37084342 Predicted intracellular proteins Evidence at protein level HPA042025, HPA055639 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 37.9 Expressed in all +SEC62 Dtrp1, HTP1, TLOC1 ENSG00000008952 SEC62 homolog, preprotein translocation factor 3 169966635-169998373 Predicted membrane proteins Evidence at protein level HPA014059, HPA061450 Approved Approved Endoplasmic reticulum
Intermediate filaments Expressed in all Expressed in all thyroid gland: 203.0 Expressed in all +RPS20 S20 ENSG00000008988 Ribosomal protein S20 8 56067295-56074581 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003570 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:1.21e-8 (unfavourable) Expressed in all Expressed in all ovary: 4364.3 Expressed in all +CSDE1 D1S155E, UNR ENSG00000009307 Cold shock domain containing E1 1 114716913-114758676 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018846, HPA052221 Enhanced Enhanced Cytosol Expressed in all Expressed in all skeletal muscle: 490.3 Expressed in all +UBE3C KIAA0010, KIAA10 ENSG00000009335 Ubiquitin protein ligase E3C 7 157138913-157269372 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039915 Approved Approved Nucleoplasm
Plasma membrane
Mitochondria Renal cancer:9.18e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 51.1 Expressed in all +REV3L POLZ, REV3 ENSG00000009413 REV3 like, DNA directed polymerase zeta catalytic subunit 6 111299028-111483715 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064853, HPA069382 Uncertain Approved Nucleoplasm Expressed in all Expressed in all cervix, uterine: 41.2 Expressed in all +TENM1 ODZ1, ODZ3, TEN-M1, TNM ENSG00000009694 Teneurin transmembrane protein 1 X 124375903-124963817 Predicted membrane proteins Evidence at protein level HPA002848 Uncertain Group enriched Mixed prostate: 4.0 Cell line enhanced MOLT-4: 4.7;RPTEC TERT1: 1.5;SCLC-21H: 2.3;U-138 MG: 3.2 +PAX7 Hup1 ENSG00000009709 Paired box 7 1 18631006-18748866 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Group enriched Group enriched 7 cerebral cortex: 1.3;skeletal muscle: 2.2 esophagus,testis: 0.2 Group enriched 7 A549: 1.3;CAPAN-2: 1.4;U-2 OS: 3.5 +MASP2 MASP1P1 ENSG00000009724 Mannan binding lectin serine peptidase 2 1 11026523-11047233 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA029313, HPA029314 Approved Supported Golgi apparatus Liver cancer:1.60e-4 (favourable) Tissue enriched Tissue enriched 18 liver: 105.5 skin: 5.7 Cell line enhanced Hep G2: 12.9 +IYD C6orf71, DEHAL1, dJ422F24.1 ENSG00000009765 Iodotyrosine deiodinase 6 150368892-150405969 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA059627 Enhanced Supported Plasma membrane Liver cancer:6.22e-4 (favourable) Tissue enriched Tissue enriched 28 thyroid gland: 794.5 kidney: 27.9 Cell line enhanced CACO-2: 1.1;SK-BR-3: 2.4 +FAM76A MGC34648 ENSG00000009780 Family with sequence similarity 76 member A 1 27725979-27763122 Predicted intracellular proteins Evidence at protein level HPA044762, HPA077897 Uncertain Approved Nucleus
Cytosol Renal cancer:2.26e-4 (favourable) Expressed in all Expressed in all testis: 32.4 Expressed in all +TRAF3IP3 T3JAM ENSG00000009790 TRAF3 interacting protein 3 1 209756032-209782320 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040796 Enhanced Approved Vesicles Breast cancer:4.11e-4 (favourable), Lung cancer:8.15e-4 (favourable) Mixed Tissue enhanced lymph node: 114.8;spleen: 82.5;tonsil: 82.8 appendix: 67.8 Cell line enhanced HDLM-2: 106.9;Karpas-707: 33.1;MOLT-4: 48.2;NB-4: 43.3;THP-1: 43.1;U-266/70: 51.7 +POMT2 LGMD2N ENSG00000009830 Protein O-mannosyltransferase 2 14 77274956-77320884 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA003663 Uncertain Liver cancer:2.40e-4 (unfavourable) Expressed in all Expressed in all testis: 28.9 Expressed in all +VTA1 C6orf55, HSPC228, My012 ENSG00000009844 Vesicle trafficking 1 6 142147162-142224689 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030968, HPA030969 Approved Supported Nucleoplasm
Vesicles
Cytosol Liver cancer:6.58e-6 (unfavourable), Breast cancer:7.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 60.9 Expressed in all +MLXIPL bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH ENSG00000009950 MLX interacting protein like 7 73593194-73624543 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA064640 Supported Nucleus Tissue enriched Tissue enhanced adipose tissue: 60.8;duodenum: 58.7 liver: 47.2 Cell line enhanced Hep G2: 33.0;K-562: 13.2;SCLC-21H: 29.5;T-47d: 10.7 +BAZ1B WBSCR10, WBSCR9, WSTF ENSG00000009954 Bromodomain adjacent to zinc finger domain 1B 7 73440398-73522278 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB037081, CAB037158, HPA067010 Supported Supported Nuclear bodies Expressed in all Expressed in all parathyroid gland: 54.8 Expressed in all +RANBP9 RanBPM ENSG00000010017 RAN binding protein 9 6 13621498-13711564 Predicted intracellular proteins Evidence at protein level CAB033767, HPA050007 Approved Supported Nucleoplasm
Cytosol Ovarian cancer:2.47e-4 (favourable), Head and neck cancer:9.97e-4 (favourable) Expressed in all Expressed in all testis: 211.6 Expressed in all +ETV7 TEL-2, TEL2 ENSG00000010030 ETS variant 7 6 36354091-36387800 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029033, HPA049689 Uncertain Enhanced Nucleoplasm Urothelial cancer:2.95e-6 (favourable), Cervical cancer:5.16e-4 (favourable), Ovarian cancer:5.32e-4 (favourable) Expressed in all Mixed skin: 19.9 Cell line enhanced BEWO: 26.5;BJ hTERT+ SV40 Large T+ RasG12V: 26.4;HDLM-2: 55.2 +SPRTN C1orf124, DKFZP547N043, DVC1, Spartan ENSG00000010072 SprT-like N-terminal domain 1 231337104-231355023 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA025073 Uncertain Supported Nucleoplasm Expressed in all Mixed testis: 25.0 Expressed in all +METTL13 CGI-01, KIAA0859 ENSG00000010165 Methyltransferase like 13 1 171781664-171814023 Predicted intracellular proteins Evidence at protein level HPA044498, HPA053705 Approved Approved Cytosol Liver cancer:5.68e-4 (unfavourable) Expressed in all Expressed in all testis: 24.7 Expressed in all +DYRK4 ENSG00000010219 Dual specificity tyrosine phosphorylation regulated kinase 4 12 4562204-4615302 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028065, HPA056073 Enhanced Enhanced Vesicles Renal cancer:6.52e-6 (unfavourable) Expressed in all Tissue enhanced testis: 66.2 epididymis: 20.7 Mixed +ZNF207 ENSG00000010244 Zinc finger protein 207 17 32350117-32381886 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017013, HPA063908 Enhanced Enhanced Nucleus Renal cancer:4.17e-8 (unfavourable), Liver cancer:7.30e-8 (unfavourable), Colorectal cancer:2.81e-4 (favourable) Expressed in all Expressed in all bone marrow: 151.3 Expressed in all +UQCRC1 D3S3191, QCR1, UQCR1 ENSG00000010256 Ubiquinol-cytochrome c reductase core protein I 3 48599002-48610976 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002815, HPA003525, CAB033782 Enhanced Supported Mitochondria
Cytosol Renal cancer:2.35e-10 (favourable) Expressed in all Expressed in all skeletal muscle: 88.3 Expressed in all +STARD3NL MENTHO, MGC3251 ENSG00000010270 STARD3 N-terminal like 7 38178222-38230671 Predicted membrane proteins Evidence at protein level HPA019204 Enhanced Supported Vesicles Liver cancer:1.44e-5 (unfavourable), Head and neck cancer:2.20e-4 (unfavourable), Pancreatic cancer:8.48e-4 (favourable) Expressed in all Expressed in all placenta: 70.6 Expressed in all +CD9 BA2, MIC3, MRP-1, P24, TSPAN29 ENSG00000010278 CD9 molecule 12 6199715-6238271 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB002490 Supported Supported Plasma membrane Renal cancer:6.49e-5 (favourable), Thyroid cancer:8.93e-5 (favourable), Pancreatic cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all esophagus: 1013.7 Cell line enhanced CAPAN-2: 1447.3;TIME: 1977.3 +HHATL C3orf3, GUP1, KIAA1173, MBOAT3, MSTP002, OACT3 ENSG00000010282 Hedgehog acyltransferase-like 3 42692663-42702827 Predicted membrane proteins Evidence at protein level HPA018174 Enhanced Tissue enhanced Tissue enhanced heart muscle: 333.1;skeletal muscle: 97.6 cerebral cortex: 53.3 Not detected +NCAPD2 CAP-D2, CNAP1, hCAP-D2, KIAA0159 ENSG00000010292 Non-SMC condensin I complex subunit D2 12 6493356-6531955 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012423, HPA036947, HPA037363 Supported Supported Nucleus
Cytosol Liver cancer:1.79e-8 (unfavourable), Renal cancer:1.13e-7 (unfavourable) Expressed in all Expressed in all lymph node: 28.7 Expressed in all +IFFO1 HOM-TES-103, IFFO ENSG00000010295 Intermediate filament family orphan 1 12 6538375-6556083 Predicted intracellular proteins Evidence at protein level HPA069344 Approved Renal cancer:7.47e-7 (unfavourable), Pancreatic cancer:6.53e-5 (favourable) Expressed in all Mixed spleen: 12.0 Mixed +GIPR ENSG00000010310 Gastric inhibitory polypeptide receptor 19 45668244-45683724 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB022710 Uncertain Tissue enriched Tissue enhanced stomach: 22.4 parathyroid gland: 12.1 Cell line enhanced HDLM-2: 9.1;HMC-1: 18.5;SCLC-21H: 16.5;U-266/70: 13.1 +PHF7 HSPC226, NYD-SP6 ENSG00000010318 PHD finger protein 7 3 52410657-52423641 Predicted intracellular proteins Evidence at protein level HPA036283, HPA070305 Enhanced Supported Nucleoplasm
Golgi apparatus Renal cancer:1.05e-6 (favourable), Breast cancer:7.38e-5 (favourable), Endometrial cancer:9.44e-5 (favourable) Expressed in all Tissue enriched 432 testis: 2183.4 rectum: 5.0 Cell line enhanced U-266/70: 13.2 +SEMA3G FLJ00014, sem2 ENSG00000010319 Semaphorin 3G 3 52433053-52445085 Predicted secreted proteins Evidence at protein level HPA001761 Uncertain Renal cancer:8.86e-5 (favourable) Expressed in all Tissue enhanced adipose tissue: 82.2 placenta: 42.3 Cell line enhanced ASC diff: 18.3;HUVEC TERT2: 6.5 +NISCH I-1, IRAS, KIAA0975 ENSG00000010322 Nischarin 3 52455118-52493071 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA023189 Approved Pancreatic cancer:1.91e-4 (favourable) Expressed in all Expressed in all testis: 96.0 Expressed in all +STAB1 CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1 ENSG00000010327 Stabilin 1 3 52495338-52524495 Predicted membrane proteins Evidence at protein level HPA005434 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:3.88e-7 (unfavourable), Colorectal cancer:7.59e-4 (unfavourable) Expressed in all Expressed in all spleen: 123.3 Group enriched 38 HUVEC TERT2: 86.2;NB-4: 93.1;TIME: 104.8 +FUZ FLJ22688, Fy ENSG00000010361 Fuzzy planar cell polarity protein 19 49806869-49817376 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041779, HPA042196 Uncertain Approved Cytosol Renal cancer:1.50e-5 (favourable) Expressed in all Expressed in all testis: 52.0 Mixed +SLC6A13 GAT2 ENSG00000010379 Solute carrier family 6 member 13 12 220621-262873 Predicted membrane proteins, Transporters Evidence at protein level HPA036449, HPA052726 Approved Nucleus
Nucleoli
Mitochondria
Cytosol Tissue enriched Tissue enriched 14 kidney: 154.0 fallopian tube: 11.3 Cell line enriched 7 RPTEC TERT1: 3.5 +IDS SIDS ENSG00000010404 Iduronate 2-sulfatase X 149476990-149521096 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Expressed in all Tissue enriched 5 cerebral cortex: 435.8 epididymis: 86.8 Expressed in all +PRSS3 PRSS4, TRY3, TRY4 ENSG00000010438 Protease, serine 3 9 33750466-33799231 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA062452, HPA063471 Supported Approved Endoplasmic reticulum
Vesicles Endometrial cancer:4.30e-4 (unfavourable) Group enriched Tissue enriched 64 pancreas: 6301.2 small intestine: 99.1 Cell line enriched 9 PC-3: 632.8 +ZNF200 ENSG00000010539 Zinc finger protein 200 16 3222325-3236221 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018981, HPA059310 Uncertain Approved Mitochondria Expressed in all Tissue enhanced testis: 31.6 placenta: 8.8 Expressed in all +CD4 ENSG00000010610 CD4 molecule 12 6786858-6820808 CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000011, HPA004252, HPA004472, CAB068180 Enhanced Supported Plasma membrane Endometrial cancer:2.16e-4 (favourable), Renal cancer:7.45e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 549.0 spleen: 220.5 Group enriched 5 HEL: 90.7;HL-60: 32.7;NB-4: 37.0;THP-1: 77.1;U-937: 84.2 +LRRC23 B7, LRPB7 ENSG00000010626 Leucine rich repeat containing 23 12 6873569-6914243 Predicted intracellular proteins Evidence at protein level HPA037766, HPA057533 Enhanced Supported Nucleoli Breast cancer:6.02e-4 (favourable) Expressed in all Group enriched 7 fallopian tube: 165.3;testis: 43.3 epididymis: 15.2 Mixed +BTK AGMX1, ATK, IMD1, PSCTK1, XLA ENSG00000010671 Bruton tyrosine kinase X 101349447-101390796 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001198, HPA002028, CAB016689 Enhanced Supported Vesicles Expressed in all Tissue enhanced lymph node: 65.2;tonsil: 70.8 spleen: 52.7 Cell line enhanced Daudi: 147.2;HEL: 256.7;HMC-1: 868.2 +HFE HLA-H ENSG00000010704 Hemochromatosis 6 26087281-26098343 Disease related genes, Predicted membrane proteins Evidence at protein level HPA017276, HPA053470 Approved Approved Nuclear membrane
Mitochondria Expressed in all Mixed parathyroid gland: 27.9 Cell line enhanced T-47d: 50.9 +SCMH1 Scml3 ENSG00000010803 Sex comb on midleg homolog 1 (Drosophila) 1 41027200-41242154 Predicted intracellular proteins Evidence at protein level HPA048898, HPA053292 Supported Nucleoplasm
Nuclear bodies Liver cancer:3.82e-4 (unfavourable), Urothelial cancer:5.80e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.0 Mixed +FYN MGC45350, SLK, SYN ENSG00000010810 FYN proto-oncogene, Src family tyrosine kinase 6 111660332-111873452 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005034, CAB018387, HPA023887, HPA063770 Approved Enhanced Plasma membrane
Cytosol Renal cancer:1.43e-4 (unfavourable), Liver cancer:1.84e-4 (favourable), Pancreatic cancer:4.78e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 166.1 Cell line enhanced U-2197: 500.5 +HIVEP2 HIV-EP2, MBP-2, MIBP1, Schnurri-2, ZAS2, ZNF40B ENSG00000010818 Human immunodeficiency virus type I enhancer binding protein 2 6 142751467-142956698 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055954 Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 31.1 Mixed +FMO1 ENSG00000010932 Flavin containing monooxygenase 1 1 171248471-171285978 Enzymes, Predicted membrane proteins Evidence at protein level HPA023680 Uncertain Renal cancer:2.81e-4 (favourable) Tissue enriched Tissue enriched 9 kidney: 203.2 small intestine: 22.8 Cell line enriched 8 HSkMC: 14.8 +ELOA SIII, TCEB3, TCEB3A ENSG00000011007 Elongin A 1 23743155-23762059 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005910 Approved Approved Nuclear speckles
Cytosol Liver cancer:1.44e-5 (unfavourable) Expressed in all Expressed in all lung: 38.5 Expressed in all +LYPLA2 APT-2 ENSG00000011009 Lysophospholipase II 1 23790970-23795539 Predicted intracellular proteins Evidence at protein level HPA063151 Uncertain Nucleoplasm
Cytosol Liver cancer:5.84e-5 (unfavourable), Renal cancer:4.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 109.2 Expressed in all +CLCN6 CLC-6, KIAA0046 ENSG00000011021 Chloride voltage-gated channel 6 1 11806096-11843144 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA032097 Approved Approved Plasma membrane
Cytosol Expressed in all Mixed cerebral cortex: 31.2 Expressed in all +MRC2 CD280, CLEC13E, ENDO180, KIAA0709 ENSG00000011028 Mannose receptor C type 2 17 62627401-62693597 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041991 Enhanced Renal cancer:4.94e-7 (unfavourable), Ovarian cancer:1.68e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 39.7 Cell line enhanced BJ: 151.9;U-138 MG: 176.9 +NME1-NME2 NM23-LV, NMELV ENSG00000011052 NME1-NME2 readthrough 17 51153590-51171744 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002169, HPA008467, HPA041113, CAB076057 Approved Supported Cytosol Glioma:8.99e-4 (favourable) Expressed in all Expressed in all appendix: 48.7 Expressed in all +SLC6A7 PROT ENSG00000011083 Solute carrier family 6 member 7 5 150189957-150222788 Predicted membrane proteins, Transporters Evidence at protein level HPA028907 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 16.9;rectum: 4.2 colon: 2.9 Not detected +TSPAN9 NET-5 ENSG00000011105 Tetraspanin 9 12 3077355-3286564 Predicted membrane proteins Evidence at protein level HPA014002 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Melanoma:4.67e-4 (unfavourable) Expressed in all Mixed heart muscle: 79.9 Cell line enhanced RH-30: 185.6 +BTBD7 FLJ10648, FUP1 ENSG00000011114 BTB domain containing 7 14 93237550-93333092 Predicted intracellular proteins Evidence at protein level HPA049926, HPA053406 Uncertain Approved Focal adhesion sites Renal cancer:1.69e-6 (favourable) Expressed in all Mixed parathyroid gland: 18.6 Expressed in all +APBA3 mint3, X11L2 ENSG00000011132 Amyloid beta precursor protein binding family A member 3 19 3750819-3761699 Predicted intracellular proteins Evidence at protein level HPA045577 Approved Approved Vesicles Pancreatic cancer:1.51e-4 (favourable), Urothelial cancer:1.83e-4 (favourable), Head and neck cancer:4.91e-4 (favourable), Endometrial cancer:5.97e-4 (favourable) Expressed in all Mixed spleen: 6.6 Mixed +MKS1 BBS13, FLJ20345, MKS, POC12 ENSG00000011143 Meckel syndrome, type 1 17 58205437-58219605 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021372, HPA021812 Enhanced Pancreatic cancer:1.25e-4 (favourable), Renal cancer:1.33e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 32.0 Expressed in all +ABHD5 CGI-58, NCIE2 ENSG00000011198 Abhydrolase domain containing 5 3 43690113-43734371 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB020685, HPA035851, HPA035852 Approved Approved Vesicles Renal cancer:9.17e-5 (favourable), Colorectal cancer:8.89e-4 (favourable) Expressed in all Expressed in all adipose tissue: 50.6 Expressed in all +ANOS1 ADMLX, KAL, KAL1, KALIG-1, WFDC19 ENSG00000011201 Anosmin 1 X 8528874-8732186 Disease related genes, Predicted secreted proteins Evidence at protein level Mixed Group enriched 5 cerebral cortex: 32.3;lung: 64.7;parathyroid gland: 48.5;thyroid gland: 15.5 testis: 7.3 Group enriched 5 NTERA-2: 36.7;U-2 OS: 18.3 +AKAP8L HAP95, NAKAP95 ENSG00000011243 A-kinase anchoring protein 8 like 19 15380048-15419141 Predicted intracellular proteins Evidence at protein level HPA042485, HPA042546 Enhanced Supported Nuclear speckles Renal cancer:1.08e-7 (unfavourable), Colorectal cancer:3.49e-4 (unfavourable), Pancreatic cancer:8.04e-4 (favourable) Expressed in all Expressed in all testis: 41.6 Expressed in all +MBTD1 FLJ20055, SA49P01 ENSG00000011258 Mbt domain containing 1 17 51177425-51260163 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021876 Approved Approved Nucleus
Cytosol Expressed in all Expressed in all testis: 46.1 Expressed in all +UTP18 CGI-48, WDR50 ENSG00000011260 UTP18, small subunit processome component 17 51260528-51297936 Predicted intracellular proteins Evidence at protein level HPA052378 Approved Supported Nucleus
Nuclear membrane
Nucleoli Liver cancer:1.99e-4 (unfavourable), Colorectal cancer:3.33e-4 (favourable) Expressed in all Expressed in all testis: 106.1 Expressed in all +RNF216 TRIAD3, UBCE7IP1, ZIN ENSG00000011275 Ring finger protein 216 7 5620047-5781739 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018955, HPA021123 Supported Supported Nucleoplasm
Cytosol Pancreatic cancer:6.24e-5 (favourable), Liver cancer:2.26e-4 (unfavourable) Expressed in all Expressed in all testis: 50.0 Expressed in all +TTC19 FLJ20343, MGC19520 ENSG00000011295 Tetratricopeptide repeat domain 19 17 15999380-16045015 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023010, HPA052380 Enhanced Enhanced Mitochondria Renal cancer:5.67e-4 (favourable) Expressed in all Expressed in all thyroid gland: 18.6 Expressed in all +PTBP1 HNRNP-I, HNRPI, pPTB, PTB, PTB-1, PTB2, PTB3, PTB4 ENSG00000011304 Polypyrimidine tract binding protein 1 19 797075-812327 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013507 Supported Supported Nucleoplasm Liver cancer:2.71e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 173.4 Expressed in all +DPF1 BAF45b, NEUD4, neuro-d4 ENSG00000011332 Double PHD fingers 1 19 38211006-38229714 Predicted intracellular proteins Evidence at protein level HPA049148 Enhanced Approved Nucleoplasm
Mitochondria
Cytosol Tissue enhanced Tissue enriched 15 cerebral cortex: 27.4 testis: 1.8 Cell line enhanced SCLC-21H: 26.9 +SYT7 IPCA-7, MGC150517, PCANAP7, SYT-VII ENSG00000011347 Synaptotagmin 7 11 61515313-61581148 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012869 Enhanced Renal cancer:1.16e-4 (unfavourable), Head and neck cancer:1.20e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 108.7;prostate: 84.8 placenta: 26.6 Cell line enhanced hTERT-HME1: 68.9;RT4: 30.1;SCLC-21H: 34.3;SK-BR-3: 31.0;T-47d: 38.2 +LARS2 KIAA0028, LEURS, MGC26121, mtLeuRS ENSG00000011376 Leucyl-tRNA synthetase 2, mitochondrial 3 45388506-45549421 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035951, HPA045450, HPA066085 Approved Supported Nucleoplasm
Mitochondria Renal cancer:1.32e-11 (favourable), Colorectal cancer:1.71e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 19.2 Expressed in all +PIK3C2A PI3K-C2alpha ENSG00000011405 Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha 11 17077730-17207983 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037641, HPA037642 Uncertain Supported Nucleus Renal cancer:1.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 94.6 Expressed in all +PLAUR CD87, UPAR, URKR ENSG00000011422 Plasminogen activator, urokinase receptor 19 43646095-43670547 Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA050843, CAB073533 Uncertain Supported Plasma membrane Renal cancer:7.83e-9 (unfavourable), Lung cancer:2.33e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 428.5 Cell line enhanced U-251 MG: 341.1;U-87 MG: 336.6;WM-115: 338.6 +ANLN ANILLIN, scra, Scraps ENSG00000011426 Anillin actin binding protein 7 36389806-36453791 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005680, CAB033902, HPA050556, CAB062547, CAB068175 Enhanced Enhanced Nucleoplasm
Midbody Renal cancer:0.00e+0 (unfavourable), Liver cancer:5.97e-7 (unfavourable), Pancreatic cancer:2.00e-6 (unfavourable), Lung cancer:6.99e-5 (unfavourable), Endometrial cancer:1.73e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 87.2 bone marrow: 23.1 Expressed in all +WIZ ZNF803 ENSG00000011451 Widely interspaced zinc finger motifs 19 15419980-15449951 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA022923, HPA023774 Supported Enhanced Nucleoplasm
Midbody Endometrial cancer:5.12e-5 (unfavourable) Expressed in all Expressed in all testis: 31.1 Expressed in all +RABGAP1 GAPCenA, TBC1D11 ENSG00000011454 RAB GTPase activating protein 1 9 122940833-123104866 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041651, HPA064860, HPA072273 Enhanced Enhanced Cytosol Renal cancer:6.06e-6 (favourable), Breast cancer:8.09e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 65.6 Expressed in all +DCN DSPG2, SLRR1B ENSG00000011465 Decorin 12 91140484-91183123 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003315, CAB017118, HPA064736, CAB068930 Enhanced Renal cancer:1.46e-5 (unfavourable) Expressed in all Expressed in all ovary: 3807.0 Cell line enhanced ASC diff: 2514.0;ASC TERT1: 1962.9;BJ hTERT+: 2379.1;HSkMC: 1868.4 +QPCTL FLJ20084 ENSG00000011478 Glutaminyl-peptide cyclotransferase like 19 45692483-45703989 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040797 Approved Supported Golgi apparatus Renal cancer:2.15e-8 (unfavourable) Expressed in all Mixed thyroid gland: 8.6 Expressed in all +PPP5C PP5, PPP5 ENSG00000011485 Protein phosphatase 5 catalytic subunit 19 46346994-46392981 Enzymes, Predicted intracellular proteins Evidence at protein level CAB022641, HPA029065, HPA056933 Approved Supported Vesicles
Cytosol Liver cancer:3.45e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 44.3 Expressed in all +CEP68 KIAA0582 ENSG00000011523 Centrosomal protein 68 2 65056366-65087004 Predicted intracellular proteins Evidence at protein level HPA040493, HPA040620 Enhanced Supported Nucleus
Microtubule organizing center Renal cancer:3.93e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 28.4 Expressed in all +MAP4K3 GLK, MAPKKKK3, RAB8IPL1 ENSG00000011566 Mitogen-activated protein kinase kinase kinase kinase 3 2 39249266-39437312 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030380 Approved Approved Centrosome Expressed in all Expressed in all thyroid gland: 40.9 Expressed in all +ZBTB32 FAXF, FAZF, Rog, TZFP, ZNF538 ENSG00000011590 Zinc finger and BTB domain containing 32 19 35704527-35717038 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA076730 Enhanced Mixed Tissue enriched 11 testis: 43.3 lymph node: 3.9 Cell line enhanced HDLM-2: 3.9;hTEC/SVTERT24-B: 2.0 +TYROBP DAP12, KARAP, PLO-SL, PLOSL ENSG00000011600 TYRO protein tyrosine kinase binding protein 19 35904401-35908295 Disease related genes, Predicted membrane proteins Evidence at protein level CAB009493, HPA041899 Enhanced Renal cancer:1.05e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 386.8 Group enriched 8 HMC-1: 603.3;THP-1: 266.6 +TMEM159 promethin ENSG00000011638 Transmembrane protein 159 16 21158377-21180616 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018033, HPA063509 Approved Approved Vesicles Renal cancer:8.11e-5 (favourable), Pancreatic cancer:1.59e-4 (unfavourable) Expressed in all Mixed skin: 45.2 Mixed +GABRA3 ENSG00000011677 Gamma-aminobutyric acid type A receptor alpha3 subunit X 152166234-152451358 FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA000839 Approved Supported Tissue enriched Tissue enriched 7 cerebral cortex: 28.8 placenta: 4.1 Cell line enhanced HMC-1: 7.4;Karpas-707: 10.3;PC-3: 7.8;U-2 OS: 7.3;U-266/84: 9.5;U-87 MG: 8.1 +BRCA1 BRCC1, FANCS, PPP1R53, RNF53 ENSG00000012048 BRCA1, DNA repair associated 17 43044295-43170245 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB001946, HPA034966, HPA057371 Enhanced Expressed in all Mixed testis: 23.9 Expressed in all +ERCC1 RAD10 ENSG00000012061 ERCC excision repair 1, endonuclease non-catalytic subunit 19 45407333-45478828 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004390, HPA029773, HPA050182, CAB072859, CAB072860 Enhanced Enhanced Nucleoplasm Renal cancer:9.00e-5 (unfavourable), Liver cancer:9.69e-4 (unfavourable) Expressed in all Expressed in all skin: 71.3 Expressed in all +CD22 SIGLEC-2, SIGLEC2 ENSG00000012124 CD22 molecule 19 35319261-35347355 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002418, HPA024353 Enhanced Mixed Tissue enhanced lymph node: 264.4;ovary: 162.2;spleen: 151.7;tonsil: 210.1 appendix: 98.1 Group enriched 11 Daudi: 201.6;REH: 76.6;U-698: 153.7;WM-115: 49.6 +SEMA3B LUCA-1, SemA, sema5, SEMAA, semaV ENSG00000012171 Semaphorin 3B 3 50267558-50277546 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030651 Approved Breast cancer:1.27e-4 (favourable) Expressed in all Mixed adrenal gland: 75.5 Cell line enhanced Hep G2: 74.9;WM-115: 171.7 +MBTPS2 KFSD, S2P ENSG00000012174 Membrane bound transcription factor peptidase, site 2 X 21839636-21885424 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA005494, CAB009486 Approved Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all Expressed in all parathyroid gland: 19.3 Expressed in all +PRICKLE3 LMO6 ENSG00000012211 Prickle planar cell polarity protein 3 X 49175264-49186528 Predicted intracellular proteins Evidence at protein level HPA000998, HPA001442 Uncertain Approved Nucleus
Plasma membrane
Centrosome Renal cancer:5.73e-6 (unfavourable), Urothelial cancer:4.84e-5 (favourable) Expressed in all Mixed skin: 11.7 Mixed +LTF HLF2 ENSG00000012223 Lactotransferrin 3 46435645-46485234 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB008646, CAB016201, HPA057177, HPA059976 Enhanced Renal cancer:6.30e-5 (favourable) Expressed in all Tissue enhanced bone marrow: 2804.3;cervix, uterine: 1030.7 seminal vesicle: 532.6 Group enriched 10 RPMI-8226: 28.9;TIME: 11.6 +EXTL3 botv, REGR ENSG00000012232 Exostosin like glycosyltransferase 3 8 28600469-28755599 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025387 Approved Liver cancer:1.14e-5 (unfavourable), Renal cancer:2.47e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 36.8 Expressed in all +NR1H4 FXR, HRR-1, HRR1, RIP14 ENSG00000012504 Nuclear receptor subfamily 1 group H member 4 12 100473708-100564413 Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters Evidence at protein level HPA047699 Approved Nucleoplasm Group enriched Tissue enhanced liver: 66.6;small intestine: 44.4 kidney: 29.9 Group enriched 26 Hep G2: 20.2;HHSteC: 14.1;RPTEC TERT1: 34.8 +ELOVL5 dJ483K16.1, HELO1, SCA38 ENSG00000012660 ELOVL fatty acid elongase 5 6 53267398-53349179 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017042, HPA047752, HPA054197 Enhanced Enhanced Endoplasmic reticulum Renal cancer:1.94e-6 (unfavourable), Thyroid cancer:6.80e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 257.0 Expressed in all +ALOX5 5-LOX ENSG00000012779 Arachidonate 5-lipoxygenase 10 45374176-45446119 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA071285 Enhanced Supported Nucleoplasm Renal cancer:1.80e-5 (unfavourable), Urothelial cancer:7.18e-4 (favourable) Expressed in all Tissue enhanced lung: 41.3 bone marrow: 28.8 Cell line enhanced BEWO: 10.4;Daudi: 22.8;HMC-1: 20.7;RT4: 14.0;U-266/70: 11.3 +KDM5D HY, HYA, JARID1D, KIAA0234, SMCY ENSG00000012817 Lysine demethylase 5D Y 19703865-19744939 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049086 Approved Nucleoli fibrillar center Head and neck cancer:3.58e-5 (favourable) Mixed Mixed small intestine: 36.5 Cell line enhanced HEL: 49.4;U-698: 32.8 +CALCOCO1 calphoglin, Cocoa, KIAA1536 ENSG00000012822 Calcium binding and coiled-coil domain 1 12 53708517-53727745 Predicted intracellular proteins Evidence at protein level HPA038313, HPA038314 Approved Enhanced Cytosol Expressed in all Expressed in all skin: 160.7 Expressed in all +UBR7 C14orf130 ENSG00000012963 Ubiquitin protein ligase E3 component n-recognin 7 (putative) 14 93207056-93229215 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000861 Approved Approved Nucleus Liver cancer:8.12e-5 (unfavourable), Renal cancer:9.76e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 23.3 Expressed in all +MAP4K5 GCKR, KHS, KHS1 ENSG00000012983 Mitogen-activated protein kinase kinase kinase kinase 5 14 50418501-50561126 Predicted intracellular proteins Evidence at protein level HPA036696 Uncertain Approved Plasma membrane
Cytosol Expressed in all Expressed in all endometrium: 55.2 Expressed in all +EHD3 PAST3 ENSG00000013016 EH domain containing 3 2 31234337-31269447 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049890, HPA049986, HPA066751 Approved Approved Plasma membrane Renal cancer:1.02e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 64.2 esophagus: 28.8 Cell line enhanced BJ: 68.8;BJ hTERT+: 162.4;HEL: 71.6 +PSMC4 MGC13687, MGC23214, MGC8570, MIP224, S6, TBP-7, TBP7 ENSG00000013275 Proteasome 26S subunit, ATPase 4 19 39971005-39981441 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002044, HPA005471 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland: 43.2 Expressed in all +MAN2B2 KIAA0935 ENSG00000013288 Mannosidase alpha class 2B member 2 4 6575175-6623362 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA037005 Uncertain Endometrial cancer:7.59e-4 (favourable) Expressed in all Expressed in all thyroid gland: 37.7 Expressed in all +SLC7A14 KIAA1613, PPP1R142 ENSG00000013293 Solute carrier family 7 member 14 3 170459584-170586074 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA045929 Approved Group enriched Tissue enriched 8 cerebral cortex: 26.7 adrenal gland: 3.1 Cell line enhanced LHCN-M2: 2.7;SCLC-21H: 3.7 +CLDN11 OSP, OTM ENSG00000013297 Claudin 11 3 170418865-170860380 Predicted membrane proteins Evidence at protein level CAB009789, HPA013166 Enhanced Breast cancer:6.31e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 89.0;testis: 183.6 ovary: 61.7 Cell line enhanced ASC diff: 254.1;ASC TERT1: 324.5;EFO-21: 266.5;HUVEC TERT2: 345.5;TIME: 539.4 +SLC25A39 CGI-69, FLJ22407 ENSG00000013306 Solute carrier family 25 member 39 17 44319625-44324870 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level HPA026785 Approved Renal cancer:3.58e-5 (favourable), Liver cancer:5.90e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 181.1 Expressed in all +MVP LRP, VAULT1 ENSG00000013364 Major vault protein 16 29820394-29848039 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level HPA002321, CAB002752, CAB022717, HPA064740 Enhanced Enhanced Cytosol Renal cancer:5.49e-5 (favourable), Breast cancer:4.51e-4 (favourable) Expressed in all Expressed in all small intestine: 165.7 Expressed in all +NUB1 BS4, NUB1L, NYREN18 ENSG00000013374 Negative regulator of ubiquitin like proteins 1 7 151341699-151378449 Predicted intracellular proteins Evidence at protein level HPA021220, HPA050722, HPA053648 Approved Enhanced Nucleus
Nucleoli Liver cancer:8.70e-4 (unfavourable) Expressed in all Expressed in all testis: 97.9 Expressed in all +PGM3 AGM1, DKFZP434B187, PAGM ENSG00000013375 Phosphoglucomutase 3 6 83161150-83193936 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004998, HPA029759, HPA029760 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:2.39e-7 (unfavourable), Cervical cancer:5.67e-4 (unfavourable), Breast cancer:8.78e-4 (unfavourable), Ovarian cancer:9.96e-4 (favourable) Expressed in all Expressed in all prostate: 82.2 Expressed in all +RWDD2A dJ747H23.2, MGC13523, RWDD2 ENSG00000013392 RWD domain containing 2A 6 83193379-83198932 Predicted intracellular proteins Evidence at protein level HPA030105, HPA030106, HPA030107 Uncertain Ovarian cancer:3.82e-5 (favourable), Pancreatic cancer:1.38e-4 (favourable), Glioma:7.17e-4 (favourable) Expressed in all Mixed prostate: 18.7 Mixed +CLK1 ENSG00000013441 CDC like kinase 1 2 200853009-200864744 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB033141, HPA062405 Approved Supported Nucleoplasm
Nuclear membrane Urothelial cancer:2.28e-4 (favourable) Expressed in all Expressed in all bone marrow: 113.5 Expressed in all +POLR3B FLJ10388, RPC2 ENSG00000013503 RNA polymerase III subunit B 12 106357658-106510198 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA036466 Supported Approved Nuclear speckles Renal cancer:1.21e-4 (favourable) Expressed in all Mixed parathyroid gland: 24.1 Expressed in all +ANGEL1 Ccr4e, KIAA0759 ENSG00000013523 Angel homolog 1 14 76786178-76826246 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000948 Uncertain Approved Nucleoplasm Lung cancer:3.43e-4 (favourable), Pancreatic cancer:5.46e-4 (favourable) Expressed in all Expressed in all testis: 68.3 Expressed in all +RNF14 ARA54, HFB30, TRIAD2 ENSG00000013561 Ring finger protein 14 5 141958328-141990291 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008716 Approved Supported Cytosol Renal cancer:1.71e-4 (favourable), Thyroid cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all testis: 137.2 Expressed in all +DNASE1L1 DNAS1L1, DNASEX, DNL1L, XIB ENSG00000013563 Deoxyribonuclease 1 like 1 X 154401238-154412112 Predicted secreted proteins Evidence at protein level HPA072635 Approved Renal cancer:2.19e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 56.6 Expressed in all +DDX11 CHL1, CHLR1, KRG2, WABS ENSG00000013573 DEAD/H-box helicase 11 12 31073845-31104791 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA065197 Supported Supported Nucleus
Nucleoli fibrillar center
Centrosome Renal cancer:5.23e-8 (unfavourable), Liver cancer:2.40e-4 (unfavourable) Expressed in all Expressed in all skin: 19.3 Expressed in all +HEBP1 HBP, HEBP ENSG00000013583 Heme binding protein 1 12 12974864-13000273 Predicted intracellular proteins Evidence at protein level HPA056417, HPA075277 Approved Approved Nucleus
Vesicles Expressed in all Expressed in all duodenum: 234.7 Expressed in all +GPRC5A PEIG-1, RAI3, RAIG1, TIG1 ENSG00000013588 G protein-coupled receptor class C group 5 member A 12 12890782-12917937 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007928, HPA046526 Enhanced Enhanced Vesicles
Plasma membrane Pancreatic cancer:4.63e-6 (unfavourable), Renal cancer:9.02e-5 (unfavourable) Mixed Tissue enhanced lung: 302.0 thyroid gland: 91.3 Cell line enhanced CAPAN-2: 1167.5;SiHa: 520.3 +MAMLD1 CG1, CXorf6, F18 ENSG00000013619 Mastermind like domain containing 1 X 150361422-150514178 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003923 Uncertain Supported Nucleoplasm Expressed in all Tissue enhanced testis: 18.7 ovary: 16.0 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 22.8;U-2197: 34.4 +CD6 Tp120 ENSG00000013725 CD6 molecule 11 60971680-61020377 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002489, CAB016252 Enhanced Head and neck cancer:5.10e-6 (favourable), Cervical cancer:1.57e-5 (favourable), Renal cancer:1.82e-4 (unfavourable), Breast cancer:1.95e-4 (favourable), Endometrial cancer:2.41e-4 (favourable) Mixed Tissue enhanced appendix: 28.5;lymph node: 49.2 tonsil: 26.8 Cell line enriched 17 MOLT-4: 31.3 +TACC3 ERIC1 ENSG00000013810 Transforming acidic coiled-coil containing protein 3 4 1721490-1745176 Predicted intracellular proteins Evidence at protein level HPA005781, HPA006050, CAB010111, HPA022039 Enhanced Enhanced Vesicles
Mitotic spindle
Microtubule organizing center
Centrosome
Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:3.30e-4 (unfavourable) Expressed in all Tissue enhanced testis: 74.9 lymph node: 55.8 Expressed in all +UFL1 KIAA0776, Maxer, NLBP, RCAD ENSG00000014123 UFM1 specific ligase 1 6 96521595-96555276 Predicted intracellular proteins Evidence at protein level HPA030558, HPA030559, HPA030560 Enhanced Supported Endoplasmic reticulum Expressed in all Expressed in all thyroid gland: 47.1 Expressed in all +POLA2 FLJ21662 ENSG00000014138 DNA polymerase alpha 2, accessory subunit 11 65261762-65305589 Predicted intracellular proteins Evidence at protein level HPA037570 Enhanced Supported Nucleoplasm Renal cancer:4.09e-8 (unfavourable), Liver cancer:2.11e-6 (unfavourable), Cervical cancer:4.61e-4 (favourable) Expressed in all Mixed lymph node,tonsil: 12.5 Expressed in all +ZC3H3 KIAA0150, ZC3HDC3 ENSG00000014164 Zinc finger CCCH-type containing 3 8 143437655-143541453 Predicted intracellular proteins Evidence at protein level HPA023658, HPA050577 Uncertain Uncertain Nucleoplasm
Golgi apparatus Renal cancer:4.38e-7 (unfavourable), Liver cancer:4.06e-4 (unfavourable) Expressed in all Expressed in all testis: 13.5 Expressed in all +CAPN1 CANP, CANPL1, muCANP, muCL ENSG00000014216 Calpain 1 11 65180566-65212006 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005992 Enhanced Supported Cytosol Renal cancer:7.06e-8 (favourable), Pancreatic cancer:4.30e-4 (unfavourable) Expressed in all Expressed in all esophagus: 243.9 Expressed in all +ACPP ACP-3, ACP3, PAP ENSG00000014257 Acid phosphatase, prostate 3 132317367-132368298 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000071, HPA004335, HPA063916 Enhanced Tissue enriched Tissue enriched 145 prostate: 6030.6 esophagus: 41.4 Cell line enhanced BJ hTERT+: 14.1;RPMI-8226: 39.1;U-87 MG: 14.6 +MDH1 ENSG00000014641 Malate dehydrogenase 1 2 63588609-63607197 Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027296, CAB047333, HPA054276 Uncertain Supported Centrosome
Cytosol Endometrial cancer:7.13e-4 (unfavourable), Renal cancer:9.95e-4 (favourable) Expressed in all Expressed in all heart muscle: 715.9 Expressed in all +SLC30A9 C4orf1, GAC63, HUEL, ZNT9 ENSG00000014824 Solute carrier family 30 member 9 4 41990472-42090457 Predicted membrane proteins, Transporters Evidence at protein level HPA004014 Approved Renal cancer:2.86e-14 (favourable) Expressed in all Expressed in all parathyroid gland: 36.1 Expressed in all +MTMR11 CRA ENSG00000014914 Myotubularin related protein 11 1 149928651-149936869 Predicted intracellular proteins Evidence at protein level HPA030351 Approved Approved Centrosome Expressed in all Mixed rectum: 27.6 Mixed +COX15 CEMCOX2 ENSG00000014919 COX15, cytochrome c oxidase assembly homolog 10 99711844-99732100 Disease related genes, Predicted membrane proteins Evidence at protein level HPA037727, HPA037728, HPA066096 Uncertain Supported Mitochondria Renal cancer:9.21e-6 (favourable) Expressed in all Expressed in all thyroid gland: 36.0 Expressed in all +CCDC88C DAPLE, HkRP2, KIAA1509, SCA40 ENSG00000015133 Coiled-coil domain containing 88C 14 91271323-91417844 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005832 Approved Approved Nucleus
Nucleoli fibrillar center Renal cancer:2.80e-4 (unfavourable), Lung cancer:2.90e-4 (favourable), Head and neck cancer:3.47e-4 (favourable) Expressed in all Mixed lymph node: 22.2 Cell line enhanced SCLC-21H: 60.6;U-266/84: 47.6 +YAF2 ENSG00000015153 YY1 associated factor 2 12 42157104-42238349 Predicted intracellular proteins Evidence at protein level HPA026867 Enhanced Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 29.5 Expressed in all +ZMYND11 BS69 ENSG00000015171 Zinc finger MYND-type containing 11 10 134465-254637 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015816 Supported Nucleoplasm Renal cancer:4.76e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 201.0 Mixed +WAS IMD2, THC, WASP, WASPA ENSG00000015285 Wiskott-Aldrich syndrome X 48676596-48691427 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA002022, CAB004290 Enhanced Renal cancer:5.58e-6 (unfavourable), Head and neck cancer:3.78e-4 (favourable), Endometrial cancer:4.95e-4 (favourable) Expressed in all Tissue enhanced appendix: 69.0;lymph node: 60.8;spleen: 68.8 bone marrow: 37.5 Cell line enhanced HMC-1: 135.1;U-937: 66.6 +DPEP1 ENSG00000015413 Dipeptidase 1 (renal) 16 89613308-89638456 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level HPA009426, HPA012783 Enhanced Approved Nucleus
Cell Junctions Renal cancer:6.84e-4 (favourable) Tissue enriched Tissue enhanced kidney: 262.6;small intestine: 418.9 pancreas: 92.8 Cell line enhanced Hep G2: 22.4;HHSteC: 11.8;U-937: 36.5 +BID ENSG00000015475 BH3 interacting domain death agonist 22 17734138-17774770 Predicted intracellular proteins Evidence at protein level HPA000722, CAB003771 Enhanced Supported Cytosol Renal cancer:3.50e-13 (unfavourable) Expressed in all Expressed in all bone marrow: 54.5 Expressed in all +MATR3 KIAA0723, MGC9105, MPD2, VCPDM ENSG00000015479 Matrin 3 5 139293648-139331677 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB033552, HPA036564, HPA036565 Enhanced Mixed Expressed in all cerebral cortex: 331.3 Expressed in all +NPC1L1 ENSG00000015520 NPC1 like intracellular cholesterol transporter 1 7 44512535-44541315 FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB070127, CAB070128 Enhanced Group enriched Tissue enhanced duodenum: 57.1;small intestine: 57.9 liver: 14.2 Group enriched 7 CACO-2: 5.9;Hep G2: 12.2;SCLC-21H: 17.4 +XYLT2 PXYLT2, XT-II ENSG00000015532 Xylosyltransferase 2 17 50346092-50363138 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA016456 Approved Nuclear bodies
Cytosol Expressed in all Expressed in all stomach: 31.5 Expressed in all +RGPD5 BS-63, DKFZp686I1842, RGP5 ENSG00000015568 RANBP2-like and GRIP domain containing 5 2 109792758-109857695 Predicted intracellular proteins Evidence at protein level HPA045704, HPA049497, HPA051675, HPA067564 Uncertain Uncertain Nuclear membrane
Vesicles Not detected Tissue enhanced testis: 6.6 duodenum: 3.2 Mixed +STMN4 RB3 ENSG00000015592 Stathmin 4 8 27235323-27258420 Predicted intracellular proteins Evidence at protein level HPA027765 Uncertain Golgi apparatus
Vesicles Tissue enriched Tissue enriched 25 cerebral cortex: 338.4 adrenal gland: 13.3 Cell line enriched 29 SCLC-21H: 102.2 +NUDCD3 KIAA1068, NudCL ENSG00000015676 NudC domain containing 3 7 44379121-44490880 Predicted intracellular proteins Evidence at protein level HPA019136, HPA019528, HPA019529 Enhanced Approved Nucleus
Plasma membrane
Cytosol Renal cancer:9.16e-4 (favourable) Expressed in all Mixed cerebral cortex: 12.4 Expressed in all +ISL1 Isl-1, ISLET1 ENSG00000016082 ISL LIM homeobox 1 5 51383391-51394738 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057416 Approved Enhanced Nucleoplasm Tissue enhanced Group enriched 5 placenta: 10.7;prostate: 15.5;seminal vesicle: 25.9;stomach: 9.8 testis: 2.9 Cell line enriched 14 SH-SY5Y: 307.2 +CHDH ENSG00000016391 Choline dehydrogenase 3 53812335-53846390 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036633, HPA058130 Enhanced Renal cancer:1.88e-8 (favourable) Mixed Tissue enhanced kidney: 40.1 small intestine: 16.4 Cell line enhanced CACO-2: 9.5;Hep G2: 24.3;T-47d: 10.6 +IL20RA IL-20R1, ZCYTOR7 ENSG00000016402 Interleukin 20 receptor subunit alpha 6 136999971-137045180 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB024990, HPA042281 Approved Approved Cytosol Endometrial cancer:1.43e-6 (favourable), Head and neck cancer:2.29e-5 (favourable) Mixed Tissue enhanced skin: 45.0 breast: 33.5 Group enriched 7 CAPAN-2: 8.4;HaCaT: 6.1;RT4: 9.2;SH-SY5Y: 11.4;T-47d: 10.0 +CLCA1 CaCC, CLCRG1 ENSG00000016490 Chloride channel accessory 1 1 86468368-86500289 Predicted secreted proteins, Transporters Evidence at protein level HPA052787, HPA059301 Enhanced Colorectal cancer:2.98e-4 (favourable) Group enriched Group enriched 8 colon: 699.6;duodenum: 882.2;rectum: 1126.3;small intestine: 1522.4 appendix: 133.7 Cell line enhanced BEWO: 1.9;NB-4: 1.5;RPMI-8226: 1.8;SH-SY5Y: 1.9;U-2197: 1.3 +CLCA4 CaCC2 ENSG00000016602 Chloride channel accessory 4 1 86547078-86580754 Predicted membrane proteins Evidence at protein level HPA017045 Uncertain Colorectal cancer:7.47e-4 (favourable), Head and neck cancer:8.63e-4 (favourable) Tissue enhanced Group enriched 6 colon: 249.5;esophagus: 365.5;rectum: 158.4 urinary bladder: 41.0 Cell line enriched 1215 RT4: 342.2 +GLT8D1 AD-017, FLJ14611 ENSG00000016864 Glycosyltransferase 8 domain containing 1 3 52694488-52706032 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010588 Approved Approved Mitochondria Endometrial cancer:2.76e-4 (favourable) Expressed in all Expressed in all testis: 116.9 Expressed in all +ATP2C1 ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1 ENSG00000017260 ATPase secretory pathway Ca2+ transporting 1 3 130850595-131016712 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB010207, HPA035116, HPA069684 Supported Enhanced Golgi apparatus Liver cancer:5.06e-6 (unfavourable), Pancreatic cancer:1.52e-4 (unfavourable), Renal cancer:1.55e-4 (favourable) Expressed in all Expressed in all prostate: 138.3 Expressed in all +IGF1 IGF-I, IGF1A, IGFI ENSG00000017427 Insulin like growth factor 1 12 102395867-102480645 Disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA048946 Approved Endometrial cancer:1.04e-4 (favourable) Mixed Tissue enhanced cervix, uterine: 126.8 smooth muscle: 98.2 Cell line enhanced ASC diff: 21.1;HDLM-2: 45.4;K-562: 19.8;U-266/70: 10.2 +SLC38A5 JM24, SN2 ENSG00000017483 Solute carrier family 38 member 5 X 48458537-48470256 Predicted membrane proteins, Transporters Evidence at protein level HPA047411 Approved Approved Vesicles
Plasma membrane
Cytosol Renal cancer:2.22e-16 (unfavourable), Pancreatic cancer:2.13e-4 (unfavourable) Expressed in all Mixed pancreas: 50.0 Cell line enhanced HBEC3-KT: 233.9;HeLa: 214.9;RPMI-8226: 374.4 +RALBP1 RIP, RIP1, RLIP76 ENSG00000017797 RalA binding protein 1 18 9475009-9538116 Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level CAB046010, HPA046651 Approved Approved Nuclear membrane
Vesicles
Cytosol Renal cancer:5.39e-6 (favourable), Ovarian cancer:8.47e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 70.4 Expressed in all +RUFY3 KIAA0871, RIPx, Singar1, ZFYVE30 ENSG00000018189 RUN and FYVE domain containing 3 4 70704204-70807315 Predicted intracellular proteins Evidence at protein level HPA022952, HPA022970 Enhanced Supported Cytosol Pancreatic cancer:8.02e-5 (favourable), Head and neck cancer:1.28e-4 (favourable), Liver cancer:8.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 143.0 Expressed in all +CNTN1 F3, GP135 ENSG00000018236 Contactin 1 12 40692442-41072418 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB025200, HPA070467 Enhanced Urothelial cancer:3.75e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 225.5 ovary: 65.6 Cell line enhanced A549: 218.0;HaCaT: 38.4;SCLC-21H: 85.1;SH-SY5Y: 46.5 +SLC11A1 LSH, NRAMP, NRAMP1 ENSG00000018280 Solute carrier family 11 member 1 2 218382029-218396894 Predicted membrane proteins, Transporters Evidence at protein level HPA029590 Uncertain Renal cancer:2.58e-8 (unfavourable) Mixed Tissue enhanced appendix: 9.1;lung: 13.0 spleen: 4.6 Not detected +WWTR1 DKFZp586I1419, TAZ ENSG00000018408 WW domain containing transcription regulator 1 3 149517235-149736714 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA007415, CAB017483, CAB068248 Enhanced Enhanced Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Mixed endometrium: 71.0 Cell line enhanced EFO-21: 230.5 +AGPS ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY ENSG00000018510 Alkylglycerone phosphate synthase 2 177392644-177559299 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030209, HPA030210, HPA030211 Supported Enhanced Peroxisomes Liver cancer:8.62e-6 (unfavourable), Pancreatic cancer:8.35e-4 (unfavourable), Renal cancer:9.45e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 50.4 Mixed +CXorf56 FLJ22965 ENSG00000018610 Chromosome X open reading frame 56 X 119538149-119565408 Predicted intracellular proteins Evidence at protein level HPA038245, HPA038617, HPA064831 Uncertain Approved Nucleus
Centrosome Breast cancer:3.45e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 24.1 Expressed in all +ATP1A2 FHM2, MHP2 ENSG00000018625 ATPase Na+/K+ transporting subunit alpha 2 1 160115759-160143591 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB022230 Approved Tissue enriched Group enriched 6 cerebral cortex: 434.2;skeletal muscle: 307.0 heart muscle: 57.5 Cell line enhanced AF22: 50.7;HHSteC: 12.3;RH-30: 16.2;U-87 MG: 10.1 +TTC27 FLJ20272 ENSG00000018699 Tetratricopeptide repeat domain 27 2 32628032-32821051 Predicted intracellular proteins Evidence at protein level HPA031246 Approved Approved Nucleoli
Mitochondria Liver cancer:1.42e-5 (unfavourable), Renal cancer:7.32e-4 (unfavourable) Expressed in all Expressed in all testis: 23.4 Expressed in all +ZNF582 FLJ30927 ENSG00000018869 Zinc finger protein 582 19 56375846-56393545 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA028858 Uncertain Approved Nucleoplasm
Cytosol Mixed Mixed thyroid gland: 12.4 Cell line enhanced HEK 293: 26.0 +VSIG2 CTH, CTXL ENSG00000019102 V-set and immunoglobulin domain containing 2 11 124747472-124752238 Predicted membrane proteins Evidence at protein level HPA035919, HPA050147 Enhanced Approved Nucleoplasm Mixed Tissue enhanced stomach: 583.7 rectum: 151.1 Group enriched 7 HEL: 14.9;RT4: 55.8 +PHLDB1 FLJ00141, KIAA0638, LL5a ENSG00000019144 Pleckstrin homology like domain family B member 1 11 118606440-118658038 Predicted intracellular proteins Evidence at protein level HPA037959, HPA038448, HPA061506 Approved Approved Nucleoplasm Renal cancer:6.36e-6 (unfavourable) Expressed in all Mixed adipose tissue: 56.5 Cell line enhanced ASC TERT1: 74.2 +MARCO SCARA2 ENSG00000019169 Macrophage receptor with collagenous structure 2 118942166-118994660 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA063793 Enhanced Approved Golgi apparatus
Vesicles Mixed Tissue enhanced appendix: 123.2;lung: 288.2 adipose tissue: 78.0 Cell line enhanced HaCaT: 1.5;THP-1: 1.7;U-2 OS: 2.7;U-266/70: 1.1 +CYP24A1 CP24, CYP24, P450-CC24 ENSG00000019186 Cytochrome P450 family 24 subfamily A member 1 20 54153449-54173973 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA022261, HPA063771 Enhanced Supported Nucleoplasm
Plasma membrane
Mitochondria Mixed Tissue enhanced endometrium: 24.8;urinary bladder: 50.8 placenta: 14.1 Group enriched 13 A549: 372.2;Hep G2: 83.4 +PRDM11 PFM8 ENSG00000019485 PR/SET domain 11 11 45095806-45235110 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA057072 Approved Mixed Mixed thyroid gland: 13.9 Mixed +SYT13 KIAA1427 ENSG00000019505 Synaptotagmin 13 11 45240301-45286319 Predicted intracellular proteins Evidence at protein level HPA046224, HPA056602 Uncertain Supported Vesicles Endometrial cancer:7.79e-5 (unfavourable) Mixed Tissue enhanced cerebral cortex: 69.9;gallbladder: 32.9 small intestine: 14.4 Group enriched 9 A549: 17.3;NTERA-2: 8.8;RPTEC TERT1: 43.3;SCLC-21H: 17.8 +SNAI2 SLUG, SLUGH, SLUGH1, SNAIL2 ENSG00000019549 Snail family transcriptional repressor 2 8 48917768-48921740 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB011671 Supported Approved Nucleus Renal cancer:4.69e-8 (unfavourable), Urothelial cancer:7.16e-4 (unfavourable), Pancreatic cancer:7.83e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 71.0 Cell line enhanced ASC diff: 194.2;ASC TERT1: 202.4;LHCN-M2: 229.9;U-138 MG: 243.9 +CD74 DHLAG ENSG00000019582 CD74 molecule 5 150401637-150412929 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level CAB002506, HPA010592 Enhanced Supported Golgi apparatus Endometrial cancer:6.53e-6 (favourable), Breast cancer:1.06e-4 (favourable) Expressed in all Expressed in all spleen: 6545.9 Cell line enhanced CAPAN-2: 1796.9;Daudi: 2297.1;HDLM-2: 4315.9;REH: 2549.8 +HGF DFNB39, F-TCF, HGFB, HPTA, SF ENSG00000019991 Hepatocyte growth factor 7 81699006-81770438 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB010333, HPA040360, HPA044088 Approved Approved Centrosome
Cytosol Renal cancer:5.59e-4 (unfavourable) Mixed Tissue enriched 16 placenta: 438.8 gallbladder: 27.5 Cell line enhanced ASC TERT1: 118.1;HHSteC: 111.7;HL-60: 63.0;hTEC/SVTERT24-B: 86.9;Karpas-707: 174.5;U-87 MG: 60.7 +ZRANB1 TRABID ENSG00000019995 Zinc finger RANBP2-type containing 1 10 124942123-124988189 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029239, HPA029240, HPA029241 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 35.9 Expressed in all +NCDN NCDN-1, NCDN-2 ENSG00000020129 Neurochondrin 1 35557473-35567274 Predicted intracellular proteins Evidence at protein level HPA023676 Enhanced Supported Supported Cytosol Liver cancer:1.91e-5 (unfavourable), Pancreatic cancer:3.73e-4 (favourable) Expressed in all Tissue enriched 13 cerebral cortex: 284.4 adrenal gland: 22.7 Expressed in all +ADGRA2 DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5 ENSG00000020181 Adhesion G protein-coupled receptor A2 8 37784191-37844896 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012393 Uncertain Renal cancer:3.18e-7 (unfavourable) Expressed in all Expressed in all seminal vesicle: 89.6 Cell line enhanced ASC diff: 66.7;ASC TERT1: 45.4;BJ hTERT+: 61.4;fHDF/TERT166: 60.9 +ZFP64 dJ548G19.1, dJ831D17.1, FLJ10734, FLJ12628, ZNF338 ENSG00000020256 ZFP64 zinc finger protein 20 52051663-52204308 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035112, HPA058387 Uncertain Approved Nucleus Liver cancer:9.86e-7 (unfavourable) Expressed in all Expressed in all skin: 13.8 Expressed in all +MNAT1 MAT1, RNF66 ENSG00000020426 MNAT1, CDK activating kinase assembly factor 14 60734742-60969953 Predicted intracellular proteins Evidence at protein level HPA000701, HPA001154, CAB004495 Approved Enhanced Nucleoplasm Head and neck cancer:2.45e-4 (unfavourable), Renal cancer:3.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 88.9 Expressed in all +SAMD4A DKFZP434H0350, hSmaug1, KIAA1053, SAMD4, Smaug, SMG, SMGA ENSG00000020577 Sterile alpha motif domain containing 4A 14 54567097-54793315 Predicted intracellular proteins Evidence at protein level HPA043061, HPA065309 Approved Approved Cell Junctions
Cytosol Expressed in all Tissue enhanced testis: 102.6 skeletal muscle: 32.7 Mixed +RUNX3 AML2, CBFA3, PEBP2A3 ENSG00000020633 Runt related transcription factor 3 1 24899511-24965121 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004195, CAB025416, HPA059006 Enhanced Supported Nucleus
Cytosol Renal cancer:5.59e-5 (unfavourable), Colorectal cancer:8.71e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 50.5 bone marrow: 45.2 Cell line enhanced HDLM-2: 125.1;Karpas-707: 125.3;SK-MEL-30: 77.0 +MRE11 ATLD, MRE11A ENSG00000020922 MRE11 homolog, double strand break repair nuclease 11 94415578-94493908 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002691, CAB004081 Supported Enhanced Nucleoplasm Liver cancer:7.14e-4 (unfavourable) Expressed in all Expressed in all endometrium: 18.7 Expressed in all +PLEKHB1 KPL1, PHR1, PHRET1 ENSG00000021300 Pleckstrin homology domain containing B1 11 73646178-73662819 Predicted intracellular proteins Evidence at protein level Renal cancer:1.99e-6 (favourable), Pancreatic cancer:6.02e-4 (favourable) Expressed in all Group enriched 7 cerebral cortex: 494.8;parathyroid gland: 148.4 thyroid gland: 48.4 Cell line enhanced EFO-21: 18.8;Hep G2: 52.2;U-266/84: 21.1 +SERPINB1 anti-elastase, EI, ELANH2, PI2 ENSG00000021355 Serpin family B member 1 6 2832332-2842006 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018871, HPA018882, HPA052642 Enhanced Supported Cytoplasmic bodies Expressed in all Expressed in all esophagus: 464.5 Cell line enhanced U-937: 105.0 +CYP3A43 ENSG00000021461 Cytochrome P450 family 3 subfamily A member 43 7 99828013-99866102 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066463, HPA072245 Supported Uncertain Cytosol Liver cancer:3.41e-4 (favourable) Tissue enriched Tissue enriched 15 liver: 22.7 testis: 1.5 Not detected +SLC7A9 CSNU3 ENSG00000021488 Solute carrier family 7 member 9 19 32830509-32869766 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA042591 Enhanced Group enriched Group enriched 10 duodenum: 79.0;kidney: 70.1;small intestine: 123.5 liver: 8.9 Group enriched 20 BEWO: 3.3;CACO-2: 6.7;Hep G2: 5.4 +SPAST ADPSP, FSP2, KIAA1083, SPG4 ENSG00000021574 Spastin 2 32063611-32157637 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017311 Approved Approved Nucleoplasm
Cytosol Liver cancer:1.62e-4 (unfavourable), Renal cancer:4.15e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 20.0 Expressed in all +NRXN3 C14orf60, KIAA0743 ENSG00000021645 Neurexin 3 14 78170373-79868290 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002727 Approved Renal cancer:1.83e-7 (favourable) Mixed Tissue enhanced cerebral cortex: 43.0;smooth muscle: 28.9 seminal vesicle: 15.3 Cell line enhanced BJ hTERT+ SV40 Large T+: 8.7;RT4: 19.0 +OSBPL5 KIAA1534, ORP5 ENSG00000021762 Oxysterol binding protein like 5 11 3087116-3166739 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA038335, HPA038712, HPA058727 Approved Enhanced Vesicles Expressed in all Mixed spleen: 19.8 Cell line enhanced NB-4: 47.3 +AQR fSAP164, IBP160, KIAA0560 ENSG00000021776 Aquarius intron-binding spliceosomal factor 15 34851782-34969839 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040624, HPA055647 Enhanced Nucleoplasm Renal cancer:4.83e-4 (favourable) Expressed in all Mixed testis: 10.1 Expressed in all +CPS1 ENSG00000021826 Carbamoyl-phosphate synthase 1 2 210477682-210679107 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003781, HPA021400 Enhanced Approved Nucleoli Liver cancer:6.93e-5 (favourable) Tissue enriched Group enriched 23 duodenum: 234.5;liver: 697.8;small intestine: 144.1 testis: 15.3 Cell line enhanced HeLa: 249.1;SK-BR-3: 84.1 +C8B ENSG00000021852 Complement C8 beta chain 1 56929210-56966140 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023694 Supported Liver cancer:9.31e-5 (favourable) Tissue enriched Tissue enriched 54 liver: 435.5 lung: 8.1 Cell line enhanced Hep G2: 1.0 +FHL1 bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA ENSG00000022267 Four and a half LIM domains 1 X 136146702-136211359 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001040, HPA001391, CAB020817 Enhanced Supported Plasma membrane
Cytosol Urothelial cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 3804.7 Cell line enhanced BJ hTERT+: 219.3 +RTFDC1 C20orf43, CDAO5, HSPC164 ENSG00000022277 Replication termination factor 2 domain containing 1 20 56468585-56519449 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053986 Approved Approved Nucleus
Nucleoli Liver cancer:1.31e-4 (unfavourable), Endometrial cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 140.4 Expressed in all +GABRA1 EJM5 ENSG00000022355 Gamma-aminobutyric acid type A receptor alpha1 subunit 5 161847063-161899981 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB022502, HPA055746 Enhanced Tissue enriched Tissue enriched 46 cerebral cortex: 85.0 adrenal gland: 1.8 Not detected +NLRP2 CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2 ENSG00000022556 NLR family pyrin domain containing 2 19 54953130-55001142 Predicted intracellular proteins Evidence at protein level HPA020765, HPA021183 Uncertain Supported Golgi apparatus
Vesicles
Cytosol Pancreatic cancer:2.91e-4 (unfavourable) Tissue enriched Mixed testis: 5.6 Cell line enhanced BEWO: 33.1;K-562: 11.5;U-266/84: 11.6 +SLC45A4 KIAA1126 ENSG00000022567 Solute carrier family 45 member 4 8 141207166-141308305 Predicted membrane proteins, Transporters Evidence at protein level HPA023154 Uncertain Approved Plasma membrane Renal cancer:1.73e-6 (favourable) Expressed in all Mixed testis: 21.0 Mixed +RNF10 KIAA0262, RIE2 ENSG00000022840 Ring finger protein 10 12 120533480-120577594 Predicted intracellular proteins Evidence at protein level HPA052643 Approved Approved Nucleoplasm
Mitochondria Liver cancer:5.30e-5 (unfavourable) Expressed in all Expressed in all testis: 179.5 Expressed in all +ZNF839 C14orf131 ENSG00000022976 Zinc finger protein 839 14 102317377-102342702 Predicted intracellular proteins Evidence at protein level HPA020434 Uncertain Approved Nucleoplasm
Plasma membrane Pancreatic cancer:4.57e-4 (favourable), Renal cancer:5.00e-4 (favourable) Expressed in all Expressed in all testis: 37.2 Expressed in all +ZDHHC6 FLJ21952, ZNF376 ENSG00000023041 Zinc finger DHHC-type containing 6 10 112424428-112446917 Enzymes, Predicted membrane proteins Evidence at protein level HPA014357 Approved Expressed in all Expressed in all small intestine: 50.7 Expressed in all +GRAMD1B KIAA1201 ENSG00000023171 GRAM domain containing 1B 11 123358428-123627774 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA008557 Approved Approved Nucleus
Nucleoli
Intermediate filaments Renal cancer:4.30e-7 (unfavourable) Mixed Tissue enhanced adrenal gland: 135.1 cerebral cortex: 39.5 Cell line enhanced A549: 57.9;HDLM-2: 155.3 +RNH1 RAI, RNH ENSG00000023191 Ribonuclease/angiogenin inhibitor 1 11 494512-507300 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039223, HPA040781 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:2.14e-5 (favourable) Expressed in all Expressed in all skin: 73.1 Expressed in all +NDUFS1 CI-75k ENSG00000023228 NADH:ubiquinone oxidoreductase core subunit S1 2 206114817-206159603 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA064605, CAB070844 Approved Supported Mitochondria Renal cancer:1.47e-12 (favourable), Breast cancer:3.85e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 71.1 Expressed in all +RB1CC1 ATG17, Cc1, DRAGOU14, FIP200, KIAA0203, PPP1R131 ENSG00000023287 RB1 inducible coiled-coil 1 8 52622456-52745843 Predicted intracellular proteins Evidence at protein level HPA024391, HPA053049 Approved Supported Nuclear membrane
Cytosol Endometrial cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all testis: 63.4 Expressed in all +ERP44 KIAA0573, PDIA10, TXNDC4 ENSG00000023318 Endoplasmic reticulum protein 44 9 99979179-100099040 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001318 Supported Head and neck cancer:5.69e-4 (unfavourable) Expressed in all Expressed in all epididymis: 47.4 Expressed in all +ALAS1 ALAS, ALAS3 ENSG00000023330 5'-aminolevulinate synthase 1 3 52198086-52214327 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017498, HPA035860 Enhanced Enhanced Nucleoplasm
Mitochondria Renal cancer:6.06e-7 (favourable), Liver cancer:1.82e-5 (favourable) Expressed in all Expressed in all adrenal gland: 761.4 Expressed in all +BIRC3 API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49 ENSG00000023445 Baculoviral IAP repeat containing 3 11 102317450-102339403 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002317 Enhanced Approved Supported Nucleoplasm
Cytosol Renal cancer:6.66e-6 (unfavourable), Pancreatic cancer:3.03e-4 (unfavourable), Breast cancer:3.60e-4 (favourable), Colorectal cancer:9.35e-4 (favourable) Expressed in all Tissue enhanced lymph node: 138.1 appendix: 117.5 Cell line enhanced CAPAN-2: 106.1;Daudi: 77.5;HDLM-2: 96.2;hTERT-HME1: 79.1 +AKAP11 AKAP220, DKFZp781I12161, FLJ11304, KIAA0629, PPP1R44, PRKA11 ENSG00000023516 A-kinase anchoring protein 11 13 42272153-42323267 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039089 Enhanced Approved Nucleoli
Plasma membrane
Cytosol Cervical cancer:9.26e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 51.6 Expressed in all +GLRX2 bA101E13.1, GRX2 ENSG00000023572 Glutaredoxin 2 1 193096468-193106114 Predicted intracellular proteins Evidence at protein level HPA023087, HPA057224 Supported Enhanced Nucleoplasm Renal cancer:3.30e-7 (unfavourable) Expressed in all Expressed in all testis: 46.2 Expressed in all +SNAPC1 PTFgamma, SNAP43 ENSG00000023608 Small nuclear RNA activating complex polypeptide 1 14 61762357-61796428 Predicted intracellular proteins Evidence at protein level HPA067076, HPA072276 Supported Nucleus
Nucleoli Expressed in all Mixed testis: 35.6 Expressed in all +DERA CGI-26, DEOC ENSG00000023697 Deoxyribose-phosphate aldolase 12 15911172-16037282 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055897 Supported Nucleus Thyroid cancer:3.64e-5 (favourable), Pancreatic cancer:1.32e-4 (unfavourable) Expressed in all Expressed in all kidney: 74.7 Expressed in all +STRAP MAWD, pt-wd, UNRIP ENSG00000023734 Serine/threonine kinase receptor associated protein 12 15882391-15903478 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027320, HPA055557, HPA073876 Approved Enhanced Nucleoplasm
Cytosol Liver cancer:6.83e-6 (unfavourable), Urothelial cancer:5.10e-4 (unfavourable), Thyroid cancer:9.07e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 144.2 Expressed in all +ABCC2 CMOAT, cMRP, DJS, MRP2 ENSG00000023839 ATP binding cassette subfamily C member 2 10 99782732-99852192 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA004860, CAB037271 Enhanced Renal cancer:1.93e-5 (unfavourable) Tissue enhanced Group enriched 10 duodenum: 43.5;gallbladder: 42.7;kidney: 20.9;liver: 67.6;small intestine: 49.5 breast: 4.4 Cell line enhanced A549: 203.8;Hep G2: 155.8 +DEF6 IBP, SLAT, SWAP70L ENSG00000023892 DEF6, guanine nucleotide exchange factor 6 35297852-35321771 Predicted intracellular proteins Evidence at protein level HPA038975, HPA038976 Enhanced Enhanced Nucleoplasm Renal cancer:1.02e-8 (unfavourable), Breast cancer:3.02e-6 (favourable), Cervical cancer:1.08e-4 (favourable), Colorectal cancer:1.71e-4 (unfavourable), Endometrial cancer:2.37e-4 (favourable) Expressed in all Mixed lymph node: 56.1 Cell line enhanced U-937: 93.5 +PLEKHO1 CKIP-1, OC120 ENSG00000023902 Pleckstrin homology domain containing O1 1 150149183-150164720 Predicted intracellular proteins Evidence at protein level HPA061018 Supported Mitochondria Renal cancer:6.47e-11 (unfavourable) Expressed in all Mixed appendix: 78.1 Mixed +GCLM GLCLR ENSG00000023909 Glutamate-cysteine ligase modifier subunit 1 93885205-93909456 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB009568, HPA023696, CAB040554 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:9.83e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 28.2 Expressed in all +UBR2 bA49A4.1, C6orf133, dJ392M17.3, KIAA0349 ENSG00000024048 Ubiquitin protein ligase E3 component n-recognin 2 6 42564062-42693504 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027869, HPA027880 Approved Approved Nucleoplasm
Plasma membrane Ovarian cancer:1.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.5 Expressed in all +EHD2 PAST2 ENSG00000024422 EH domain containing 2 19 47713343-47743134 Predicted intracellular proteins Evidence at protein level HPA047394, HPA049890, HPA049986, HPA066751 Approved Supported Plasma membrane Renal cancer:3.98e-4 (unfavourable), Ovarian cancer:8.75e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 208.8 smooth muscle: 111.7 Mixed +DEPDC1 DEP.8, DEPDC1A, FLJ20354, SDP35 ENSG00000024526 DEP domain containing 1 1 68474152-68497221 Predicted intracellular proteins Evidence at protein level CAB017845 Approved Supported Nucleus
Nucleoli fibrillar center Colorectal cancer:8.70e-5 (favourable) Mixed Tissue enhanced testis: 14.5 lymph node: 5.8 Mixed +CCDC28A C6orf80, CCRL1AP, DKFZp586D0623 ENSG00000024862 Coiled-coil domain containing 28A 6 138773509-138793319 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055125 Approved Approved Cytosol Renal cancer:1.11e-5 (favourable) Expressed in all Expressed in all thyroid gland: 90.7 Expressed in all +RRAGD bA11D8.2.1, DKFZP761H171 ENSG00000025039 Ras related GTP binding D 6 89364636-89412270 Predicted intracellular proteins Evidence at protein level HPA068664 Approved Approved Nucleoplasm
Centrosome Renal cancer:8.47e-8 (favourable), Liver cancer:7.80e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 46.8 Cell line enhanced Karpas-707: 45.9;SCLC-21H: 39.1;U-266/70: 61.2 +HSF2 ENSG00000025156 Heat shock transcription factor 2 6 122399546-122433119 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB016067, HPA031455 Approved Supported Nucleoplasm Liver cancer:1.51e-6 (unfavourable), Renal cancer:7.65e-4 (unfavourable) Expressed in all Expressed in all testis: 71.4 Expressed in all +PHF20 C20orf104, dJ1121G12.1, TDRD20A ENSG00000025293 PHD finger protein 20 20 35771974-35950381 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029619, HPA029620, HPA029621 Approved Supported Nucleoplasm
Nuclear membrane
Cytosol Liver cancer:2.49e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 22.4 Expressed in all +HSD17B6 HSE, RODH, SDR9C6 ENSG00000025423 Hydroxysteroid 17-beta dehydrogenase 6 12 56752161-56787790 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059141 Enhanced Approved Nucleus
Vesicles Liver cancer:6.32e-4 (favourable) Tissue enriched Tissue enriched 10 liver: 930.6 seminal vesicle: 96.0 Cell line enhanced SCLC-21H: 12.9 +NR1H3 LXR-a, RLD-1 ENSG00000025434 Nuclear receptor subfamily 1 group H member 3 11 47248300-47269032 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036443, CAB037109 Approved Renal cancer:1.40e-5 (unfavourable), Urothelial cancer:3.40e-4 (favourable), Endometrial cancer:5.05e-4 (favourable), Liver cancer:5.60e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 55.2 Mixed +TYMP ECGF1, MNGIE ENSG00000025708 Thymidine phosphorylase 22 50525752-50530056 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000530, HPA001072, CAB002518 Enhanced Approved Nuclear bodies
Golgi apparatus Renal cancer:3.50e-8 (unfavourable), Endometrial cancer:4.34e-5 (favourable) Expressed in all Tissue enhanced appendix: 100.6 spleen: 53.1 Cell line enhanced CAPAN-2: 37.3;HHSteC: 84.7;Karpas-707: 72.1;U-266/70: 36.4 +NCAPH2 384D8-2, CAP-H2, hCAP-H2 ENSG00000025770 Non-SMC condensin II complex subunit H2 22 50508216-50523472 Predicted intracellular proteins Evidence at protein level HPA067932, HPA069056 Enhanced Enhanced Nucleoplasm
Cytokinetic bridge Cervical cancer:2.24e-8 (favourable), Liver cancer:8.25e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 49.4 Expressed in all +TOMM34 HTOM34P, TOM34 ENSG00000025772 Translocase of outer mitochondrial membrane 34 20 44942130-44960486 Predicted intracellular proteins Evidence at protein level HPA018845, HPA056875 Enhanced Enhanced Cytosol Liver cancer:8.71e-6 (unfavourable), Head and neck cancer:4.47e-5 (unfavourable), Thyroid cancer:5.45e-4 (favourable) Expressed in all Expressed in all testis: 182.2 Expressed in all +SEC63 DNAJC23, ERdj2, PRO2507, SEC63L ENSG00000025796 SEC63 homolog, protein translocation regulator 6 107867756-107958189 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA053295, HPA060535 Enhanced Supported Endoplasmic reticulum Breast cancer:3.32e-4 (unfavourable), Cervical cancer:4.01e-4 (unfavourable), Renal cancer:6.16e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 87.4 Expressed in all +KPNA6 FLJ11249, IPOA7, KPNA7, MGC17918 ENSG00000025800 Karyopherin subunit alpha 6 1 32108038-32176568 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA018863 Supported Approved Nucleoplasm
Cytosol Liver cancer:9.28e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.4 Expressed in all +VIM ENSG00000026025 Vimentin 10 17228259-17237593 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000080, HPA001762, CAB058687 Enhanced Approved Intermediate filaments Renal cancer:8.69e-8 (unfavourable), Endometrial cancer:9.75e-6 (favourable) Expressed in all Expressed in all ovary: 4304.6 Cell line enhanced ASC TERT1: 12818.5 +FAS APO-1, APT1, CD95, FAS1, TNFRSF6 ENSG00000026103 Fas cell surface death receptor 10 88990582-89015785 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA027444 Enhanced Approved Plasma membrane
Cytosol Expressed in all Mixed rectum: 32.9 Cell line enhanced Karpas-707: 104.1 +RNASET2 bA514O12.3, FLJ10907, RNASE6PL ENSG00000026297 Ribonuclease T2 6 166929504-166957191 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029013, HPA066509 Approved Renal cancer:1.70e-14 (unfavourable) Expressed in all Expressed in all spleen: 279.9 Cell line enhanced EFO-21: 187.2;THP-1: 346.2 +CD44 CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1 ENSG00000026508 CD44 molecule (Indian blood group) 11 35138870-35232402 Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000112, CAB000316, HPA005785 Enhanced Enhanced Golgi apparatus
Plasma membrane Renal cancer:1.78e-8 (unfavourable) Expressed in all Expressed in all skin: 530.1 Mixed +KCNG1 K13, KCNG, kH2, Kv6.1 ENSG00000026559 Potassium voltage-gated channel modifier subfamily G member 1 20 51003656-51023129 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA039530, HPA040024 Approved Approved Vesicles Tissue enhanced Tissue enhanced endometrium: 23.4;seminal vesicle: 18.1 placenta: 10.1 Cell line enhanced hTCEpi: 38.3;U-138 MG: 39.5 +AGPAT4 dJ473J16.2, LPAAT-delta ENSG00000026652 1-acylglycerol-3-phosphate O-acyltransferase 4 6 161129979-161274061 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053287, HPA060525 Approved Approved Nucleoli
Golgi apparatus
Vesicles Cervical cancer:1.45e-4 (unfavourable), Renal cancer:4.08e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 24.7 placenta: 12.3 Cell line enhanced AF22: 25.4 +SLAMF7 19A, CD319, CRACC, CS1 ENSG00000026751 SLAM family member 7 1 160739057-160754821 CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB015445, HPA055945, HPA061654 Enhanced Approved Vesicles Renal cancer:8.57e-5 (unfavourable), Ovarian cancer:3.93e-4 (favourable) Mixed Mixed spleen: 58.3 Group enriched 7 SK-MEL-30: 45.6;U-266/70: 216.2 +BTN3A1 BT3.1, BTF5, BTN3.1, CD277 ENSG00000026950 Butyrophilin subfamily 3 member A1 6 26402237-26415216 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012565 Approved Uncertain Vesicles Renal cancer:4.15e-5 (unfavourable), Urothelial cancer:4.81e-4 (favourable) Expressed in all Expressed in all spleen: 112.6 Mixed +MIPEP MIP ENSG00000027001 Mitochondrial intermediate peptidase 13 23730189-23889419 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA030676, HPA031669, HPA031670 Approved Enhanced Mitochondria Renal cancer:7.66e-12 (favourable) Expressed in all Expressed in all fallopian tube: 27.4 Expressed in all +PRKCH PKC-L, PKCL, PRKCL ENSG00000027075 Protein kinase C eta 14 61187559-61550976 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026294, HPA053709 Approved Approved Plasma membrane
Cytosol Head and neck cancer:8.55e-6 (favourable) Expressed in all Expressed in all lymph node: 61.7 Cell line enhanced BEWO: 78.7;HUVEC TERT2: 90.5;MOLT-4: 60.3;TIME: 58.5 +INSRR IRR ENSG00000027644 Insulin receptor related receptor 1 156840063-156859018 Enzymes, Predicted membrane proteins Evidence at protein level HPA025285 Uncertain Not detected Tissue enhanced adrenal gland: 1.8;kidney: 1.4;testis: 2.2 prostate: 0.6 Group enriched 10 SCLC-21H: 5.5;SH-SY5Y: 17.2 +IFNGR1 CD119, IFNGR ENSG00000027697 Interferon gamma receptor 1 6 137197484-137219449 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025889, HPA063871 Approved Renal cancer:5.48e-4 (unfavourable) Expressed in all Expressed in all spleen: 221.9 Expressed in all +B4GALT7 beta4Gal-T7, XGALT-1 ENSG00000027847 Beta-1,4-galactosyltransferase 7 5 177600100-177610347 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042330 Supported Glioma:1.90e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 27.3 Expressed in all +SH2D2A F2771, TSAd ENSG00000027869 SH2 domain containing 2A 1 156806243-156816862 Predicted intracellular proteins Evidence at protein level Renal cancer:5.26e-12 (unfavourable), Urothelial cancer:1.31e-4 (favourable), Breast cancer:4.96e-4 (favourable) Expressed in all Tissue enhanced appendix: 15.0 lymph node: 10.5 Cell line enhanced HDLM-2: 42.7;HMC-1: 29.0;Karpas-707: 57.7 +VRK2 ENSG00000028116 Vaccinia related kinase 2 2 57907651-58159920 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB046459, HPA047503 Approved Supported Endoplasmic reticulum Liver cancer:6.32e-6 (unfavourable), Renal cancer:4.66e-5 (unfavourable), Pancreatic cancer:4.65e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 29.1 Mixed +TNFRSF1B CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80 ENSG00000028137 TNF receptor superfamily member 1B 1 12167003-12209228 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004796 Approved Renal cancer:8.35e-5 (unfavourable), Testis cancer:8.68e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 100.4 spleen: 77.8 Cell line enhanced CAPAN-2: 31.7;K-562: 41.3;THP-1: 35.7;U-87 MG: 34.0 +VEZT DKFZP761C241 ENSG00000028203 Vezatin, adherens junctions transmembrane protein 12 95217746-95302790 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004811, HPA017066 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.93e-5 (unfavourable), Liver cancer:1.71e-4 (unfavourable), Stomach cancer:3.68e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 31.4 Expressed in all +POU2F2 OCT2, OTF2 ENSG00000028277 POU class 2 homeobox 2 19 42086110-42196585 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002513, HPA049056, HPA062096, HPA064404 Enhanced Enhanced Nucleoplasm
Vesicles Renal cancer:7.57e-11 (unfavourable) Mixed Tissue enhanced lymph node: 62.3;tonsil: 44.4 appendix,spleen: 37.6 Cell line enhanced BJ hTERT+: 42.5;Daudi: 81.0;hTEC/SVTERT24-B: 42.8;U-266/70: 57.7;U-266/84: 54.8;U-698: 61.5 +BRD9 FLJ13441 ENSG00000028310 Bromodomain containing 9 5 850291-892824 Predicted intracellular proteins Evidence at protein level HPA021465, HPA023197 Uncertain Approved Nucleoplasm Liver cancer:5.88e-7 (unfavourable), Renal cancer:2.37e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 14.7 Expressed in all +SNX1 HsT17379, MGC8664, SNX1A, Vps5 ENSG00000028528 Sorting nexin 1 15 64094123-64146090 Predicted intracellular proteins Evidence at protein level HPA047373, HPA052761 Approved Enhanced Endosomes
Lysosomes Renal cancer:9.88e-6 (favourable) Expressed in all Expressed in all thyroid gland: 163.5 Expressed in all +TBPL1 STUD, TLF, TLP, TRF2 ENSG00000028839 TATA-box binding protein like 1 6 133952170-133990432 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071810, HPA071813 Enhanced Enhanced Nucleoplasm
Nucleoli Liver cancer:7.91e-5 (unfavourable), Renal cancer:4.14e-4 (unfavourable), Glioma:4.67e-4 (favourable), Pancreatic cancer:7.23e-4 (favourable) Expressed in all Tissue enriched 8 testis: 227.4 thyroid gland: 28.2 Expressed in all +ARNTL2 bHLHe6, BMAL2, CLIF, MOP9, PASD9 ENSG00000029153 Aryl hydrocarbon receptor nuclear translocator like 2 12 27332854-27425289 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059074, HPA065355 Uncertain Enhanced Nucleus
Nucleoli Pancreatic cancer:5.29e-6 (unfavourable), Renal cancer:1.56e-5 (unfavourable) Mixed Tissue enhanced esophagus: 31.2 tonsil: 20.2 Cell line enhanced U-2197: 148.2 +BCLAF1 BTF, KIAA0164 ENSG00000029363 BCL2 associated transcription factor 1 6 136256627-136289851 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006484, HPA006669, HPA027770 Enhanced Enhanced Nuclear speckles Breast cancer:1.64e-4 (unfavourable), Colorectal cancer:3.44e-4 (favourable) Expressed in all Expressed in all bone marrow: 88.4 Expressed in all +SLC39A9 FLJ11274 ENSG00000029364 Solute carrier family 39 member 9 14 69398015-69462388 Predicted membrane proteins, Transporters Evidence at protein level HPA007921, HPA075390 Enhanced Approved Endoplasmic reticulum Renal cancer:1.05e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 45.0 Expressed in all +ANK1 ANK, SPH1 ENSG00000029534 Ankyrin 1 8 41653220-41896762 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA004842, HPA056953 Supported Mixed Tissue enriched 5 skeletal muscle: 348.3 heart muscle: 63.9 Group enriched 5 HEL: 84.7;K-562: 96.3;RH-30: 157.8 +IBSP BSP, BSP-II, SP-II ENSG00000029559 Integrin binding sialoprotein 4 87799581-87812435 Cancer-related genes, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 1.6;cervix, uterine: 1.3 gallbladder,placenta: 0.3 Cell line enriched 6 U-138 MG: 7.3 +TFB1M CGI-75, mtTFB ENSG00000029639 Transcription factor B1, mitochondrial 6 155257509-155314493 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029428 Approved Expressed in all Expressed in all testis: 19.6 Expressed in all +RABEP1 neurocrescin, RAB5EP, rabaptin-5, RABPT5 ENSG00000029725 Rabaptin, RAB GTPase binding effector protein 1 17 5282265-5385812 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB004549, HPA019669, HPA024235, HPA024691 Enhanced Enhanced Vesicles Pancreatic cancer:6.43e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 88.9 Expressed in all +HMGB3 HMG2A, HMG4, MGC90319 ENSG00000029993 High mobility group box 3 X 150980509-150990775 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062583 Enhanced Approved Nucleus
Nucleoli Ovarian cancer:9.85e-5 (favourable), Renal cancer:6.15e-4 (favourable) Expressed in all Expressed in all placenta: 196.4 Expressed in all +NUP160 FLJ22583, KIAA0197 ENSG00000030066 Nucleoporin 160 11 47778087-47848555 Predicted intracellular proteins, Transporters Evidence at protein level Expressed in all Expressed in all parathyroid gland: 39.6 Expressed in all +BAK1 BAK, BCL2L7, CDN1 ENSG00000030110 BCL2 antagonist/killer 1 6 33572547-33580293 Predicted membrane proteins, Transporters Evidence at protein level CAB005029 Enhanced Renal cancer:1.64e-5 (unfavourable), Endometrial cancer:1.71e-4 (unfavourable), Liver cancer:4.52e-4 (unfavourable), Lung cancer:5.64e-4 (unfavourable) Expressed in all Expressed in all duodenum: 47.9 Expressed in all +MUSK ENSG00000030304 Muscle associated receptor tyrosine kinase 9 110668771-110801620 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Not detected Mixed testis: 3.0 Group enriched 19 LHCN-M2: 20.0;RH-30: 23.3 +IKZF2 Helios, ZNFN1A2 ENSG00000030419 IKAROS family zinc finger 2 2 212999691-213152427 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059142 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Mixed Mixed esophagus: 21.4 Cell line enhanced MOLT-4: 24.8;RT4: 22.8 +GRN CLN11, PCDGF, PGRN ENSG00000030582 Granulin precursor 17 44345086-44353102 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008763, CAB019394, HPA028747 Approved Enhanced Endoplasmic reticulum
Endosomes
Lysosomes Glioma:6.36e-4 (unfavourable) Expressed in all Expressed in all lung: 439.4 Expressed in all +FAM13B ARHGAP49, C5orf5, FAM13B1, KHCHP, N61 ENSG00000031003 Family with sequence similarity 13 member B 5 137937960-138051961 Predicted intracellular proteins Evidence at protein level HPA036525, HPA041819, HPA071936 Uncertain Approved Nucleoplasm Renal cancer:3.55e-5 (favourable) Expressed in all Expressed in all testis: 63.4 Expressed in all +ARHGAP31 CDGAP ENSG00000031081 Rho GTPase activating protein 31 3 119294373-119420714 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036380 Approved Renal cancer:8.45e-4 (favourable) Expressed in all Mixed lung: 29.1 Cell line enhanced HUVEC TERT2: 29.2;TIME: 31.7 +CENPQ C6orf139, CENP-Q, FLJ10545 ENSG00000031691 Centromere protein Q 6 49463378-49493107 Predicted intracellular proteins Evidence at protein level HPA029043, HPA046634, HPA054965 Approved Enhanced Nucleoplasm Liver cancer:2.21e-5 (unfavourable), Endometrial cancer:4.64e-4 (unfavourable), Ovarian cancer:6.26e-4 (favourable) Expressed in all Mixed testis: 11.0 Expressed in all +SARS SERS ENSG00000031698 Seryl-tRNA synthetase 1 109213918-109238169 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016939, HPA064668 Uncertain Enhanced Cytosol Liver cancer:6.13e-5 (unfavourable), Head and neck cancer:5.75e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 240.7 Expressed in all +RANBP3 ENSG00000031823 RAN binding protein 3 19 5916139-5978142 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA043375, HPA043389 Enhanced Enhanced Nucleoplasm Endometrial cancer:1.22e-5 (favourable), Pancreatic cancer:4.14e-4 (favourable), Thyroid cancer:8.14e-4 (favourable) Expressed in all Expressed in all testis: 60.1 Expressed in all +ARID4A RBBP1, RBP-1, RBP1 ENSG00000032219 AT-rich interaction domain 4A 14 58298385-58373887 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048899 Supported Nucleoplasm
Plasma membrane
Cytosol Head and neck cancer:1.91e-4 (favourable), Lung cancer:7.82e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 24.0 Expressed in all +TSSC1 ENSG00000032389 Tumor suppressing subtransferable candidate 1 2 3188925-3377882 Predicted intracellular proteins Evidence at protein level HPA031231, HPA031232, HPA031233, HPA031234 Approved Supported Nucleus
Nucleoli
Intermediate filaments Liver cancer:3.67e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 34.8 Expressed in all +PNPLA6 iPLA2delta, NTE, SPG39, sws ENSG00000032444 Patatin like phospholipase domain containing 6 19 7534004-7561764 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007522 Uncertain Pancreatic cancer:3.51e-5 (favourable), Head and neck cancer:5.25e-4 (favourable), Renal cancer:7.53e-4 (favourable) Expressed in all Expressed in all testis: 49.1 Expressed in all +IFT88 D13S1056E, hTg737, MGC26259, Tg737, TTC10 ENSG00000032742 Intraflagellar transport 88 13 20567069-20691437 Predicted intracellular proteins Evidence at protein level Renal cancer:1.33e-4 (favourable), Pancreatic cancer:5.17e-4 (favourable) Expressed in all Expressed in all testis: 126.6 Expressed in all +ALG1 CDG1K, HMAT1, HMT-1, Mat-1 ENSG00000033011 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 16 5033960-5087379 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA060392 Approved Approved Nucleoli fibrillar center
Endoplasmic reticulum Colorectal cancer:5.79e-4 (favourable), Testis cancer:6.93e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.4 Expressed in all +ZCCHC8 DKFZp434E2220 ENSG00000033030 Zinc finger CCHC-type containing 8 12 122471600-122501073 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA037483, HPA037484 Supported Enhanced Nucleoplasm
Nuclear bodies Renal cancer:5.36e-4 (unfavourable), Melanoma:7.40e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 33.1 Expressed in all +ABCF2 ABC28, EST133090, HUSSY-18, M-ABC1 ENSG00000033050 ATP binding cassette subfamily F member 2 7 151207837-151227230 Predicted intracellular proteins Evidence at protein level HPA020091, CAB020682, HPA021815, HPA030388 Enhanced Supported Cytosol Liver cancer:9.52e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 52.2 Expressed in all +CHPF2 ChSy-3, CSGlcA-T, KIAA1402 ENSG00000033100 Chondroitin polymerizing factor 2 7 151232489-151238827 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020992 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:2.51e-4 (favourable), Liver cancer:9.47e-4 (unfavourable) Expressed in all Expressed in all gallbladder,spleen: 23.5 Expressed in all +LRRC7 densin-180, KIAA1365 ENSG00000033122 Leucine rich repeat containing 7 1 69568398-70151945 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced cerebral cortex: 14.4 testis,thyroid gland: 4.2 Cell line enhanced HaCaT: 13.5;HEL: 41.5;SCLC-21H: 6.0 +FUT8 ENSG00000033170 Fucosyltransferase 8 14 65410592-65744121 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017129, HPA040863, HPA043410 Enhanced Enhanced Golgi apparatus
Cytosol Expressed in all Mixed cerebral cortex: 31.5 Expressed in all +UBA6 FLJ10808, UBE1L2 ENSG00000033178 Ubiquitin like modifier activating enzyme 6 4 67612652-67701179 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037001 Uncertain Enhanced Nucleoplasm
Cytosol Renal cancer:7.01e-5 (unfavourable) Expressed in all Expressed in all testis: 18.7 Expressed in all +GAB2 KIAA0571 ENSG00000033327 GRB2 associated binding protein 2 11 78215297-78418348 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA000271, HPA001368, CAB022159 Enhanced Supported Plasma membrane Renal cancer:9.32e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 35.5 Cell line enhanced SH-SY5Y: 66.1 +ATP6V0A1 a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1 ENSG00000033627 ATPase H+ transporting V0 subunit a1 17 42458844-42522611 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA022144 Enhanced Approved Nuclear speckles
Golgi apparatus
Vesicles
Cytosol Renal cancer:1.28e-4 (favourable), Pancreatic cancer:2.05e-4 (favourable), Urothelial cancer:6.90e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 200.9 Mixed +PIAS1 DDXBP1, GBP, GU/RH-II, ZMIZ3 ENSG00000033800 Protein inhibitor of activated STAT 1 15 68054179-68198603 Predicted intracellular proteins Evidence at protein level HPA005743, CAB012304 Supported Approved Microtubules Expressed in all Expressed in all testis: 37.7 Expressed in all +SLC4A7 NBC3, SBC2, SLC4A6 ENSG00000033867 Solute carrier family 4 member 7 3 27372721-27484420 Predicted membrane proteins, Transporters Evidence at protein level CAB022494, HPA035857 Enhanced Supported Plasma membrane
Focal adhesion sites
Cytosol Renal cancer:7.91e-6 (unfavourable) Expressed in all Tissue enhanced duodenum: 57.7 breast: 23.8 Expressed in all +APBA2 D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11L ENSG00000034053 Amyloid beta precursor protein binding family A member 2 15 28884483-29118315 Predicted intracellular proteins Evidence at protein level CAB037065 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 12.2 spleen: 3.3 Cell line enhanced HEL: 7.6;SH-SY5Y: 21.2;U-937: 11.6 +MAP2K3 MAPKK3, MEK3, MKK3, PRKMK3 ENSG00000034152 Mitogen-activated protein kinase kinase 3 17 21284672-21315240 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB018548 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all bone marrow: 129.9 Expressed in all +EFCAB1 FLJ11767 ENSG00000034239 EF-hand calcium binding domain 1 8 48710789-48735311 Predicted intracellular proteins Evidence at protein level HPA023527, HPA069955 Enhanced Approved Nucleoplasm
Plasma membrane Tissue enhanced Tissue enhanced fallopian tube: 149.8;testis: 47.1 ovary: 23.9 Cell line enhanced A-431: 5.8;ASC TERT1: 4.4;CAPAN-2: 2.8;SCLC-21H: 5.8 +TMSB10 TB10 ENSG00000034510 Thymosin beta 10 2 84905625-84906675 Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:8.49e-7 (unfavourable), Thyroid cancer:4.97e-5 (favourable) Expressed in all Expressed in all epididymis: 3706.7 Expressed in all +ASTE1 HT001 ENSG00000034533 Asteroid homolog 1 (Drosophila) 3 131013875-131027649 Predicted intracellular proteins Evidence at protein level HPA037010, HPA037011 Enhanced Approved Endoplasmic reticulum Liver cancer:4.03e-5 (unfavourable), Endometrial cancer:2.34e-4 (unfavourable), Cervical cancer:3.09e-4 (favourable) Expressed in all Mixed thyroid gland: 11.7 Expressed in all +RNF19A DKFZp566B1346, dorfin, RNF19 ENSG00000034677 Ring finger protein 19A, RBR E3 ubiquitin protein ligase 8 100257060-100336218 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB011455, HPA023652 Approved Urothelial cancer:3.28e-5 (favourable), Renal cancer:7.99e-5 (unfavourable) Expressed in all Expressed in all testis: 95.3 Expressed in all +PEX3 ENSG00000034693 Peroxisomal biogenesis factor 3 6 143450807-143490010 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA042830, HPA058006 Enhanced Supported Nucleoplasm
Peroxisomes Renal cancer:3.80e-4 (favourable) Expressed in all Expressed in all adrenal gland: 54.3 Expressed in all +GABARAPL2 ATG8, ATG8C, GATE-16, GATE16, GEF2 ENSG00000034713 GABA type A receptor associated protein like 2 16 75566351-75577881 Predicted intracellular proteins Evidence at protein level HPA036726 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:5.95e-8 (favourable), Head and neck cancer:7.63e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 319.3 Expressed in all +MYOC GLC1A, JOAG1, TIGR ENSG00000034971 Myocilin 1 171635417-171652683 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA027364 Approved Tissue enriched Tissue enhanced adipose tissue: 45.4 esophagus: 21.4 Not detected +SH3YL1 DKFZP586F1318, Ray ENSG00000035115 SH3 and SYLF domain containing 1 2 217730-266398 Predicted intracellular proteins Evidence at protein level HPA030926, HPA030927 Approved Approved Nucleus Renal cancer:7.70e-4 (favourable) Expressed in all Expressed in all kidney: 150.0 Mixed +FAM136A FLJ14668 ENSG00000035141 Family with sequence similarity 136 member A 2 70295975-70302090 Predicted intracellular proteins Evidence at protein level HPA030103, HPA030104 Enhanced Approved Mitochondria Renal cancer:1.33e-6 (unfavourable), Liver cancer:2.66e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 34.5 Expressed in all +VCL ENSG00000035403 Vinculin 10 73995193-74121363 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002131, CAB002453, HPA063777 Enhanced Enhanced Focal adhesion sites Pancreatic cancer:2.75e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 326.5 Expressed in all +DEPDC1B BRCC3, XTP1 ENSG00000035499 DEP domain containing 1B 5 60596912-60700190 Predicted intracellular proteins Evidence at protein level HPA038255, HPA072558 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Lung cancer:6.93e-5 (unfavourable), Colorectal cancer:2.42e-4 (favourable), Liver cancer:3.08e-4 (unfavourable), Endometrial cancer:8.55e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 33.0;testis: 22.6 lymph node: 10.8 Mixed +DAPK2 DRP-1, MGC119312 ENSG00000035664 Death associated protein kinase 2 15 63907036-64072033 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA071581 Supported Golgi apparatus
Vesicles Lung cancer:5.63e-4 (favourable) Tissue enriched Tissue enhanced thyroid gland: 49.1 lung: 29.9 Cell line enhanced HMC-1: 16.0 +NSMAF FAN, GRAMD5 ENSG00000035681 Neutral sphingomyelinase activation associated factor 8 58583504-58659844 Predicted intracellular proteins Evidence at protein level HPA023067, HPA023148, HPA023151 Uncertain Approved Nucleoli Renal cancer:4.61e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.6 Expressed in all +ADSS ENSG00000035687 Adenylosuccinate synthase 1 244408494-244452134 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024400 Enhanced Supported Plasma membrane
Cytosol Expressed in all Expressed in all testis: 117.0 Expressed in all +STAP1 BRDG1, STAP-1 ENSG00000035720 Signal transducing adaptor family member 1 4 67558728-67607337 Predicted intracellular proteins Evidence at protein level HPA038529 Enhanced Uncertain Nucleoplasm
Vesicles Tissue enriched Group enriched 6 appendix: 23.8;kidney: 13.2;lymph node: 59.6;spleen: 26.6;tonsil: 56.3 testis: 6.1 Cell line enhanced Daudi: 141.5;U-698: 60.7;U-937: 22.3 +TIMP2 CSC-21K ENSG00000035862 TIMP metallopeptidase inhibitor 2 17 78852977-78925387 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010203 Approved Expressed in all Expressed in all ovary: 1178.9 Cell line enhanced ASC TERT1: 1134.2 +RFC1 A1, MHCBFB, PO-GA, RFC140 ENSG00000035928 Replication factor C subunit 1 4 39287456-39366375 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009520, HPA046116, HPA069306 Supported Enhanced Nucleus Colorectal cancer:4.43e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 66.7 Expressed in all +TBC1D23 FLJ11046 ENSG00000036054 TBC1 domain family member 23 3 100261000-100325251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038151, HPA038152 Approved Enhanced Golgi apparatus Endometrial cancer:5.37e-4 (unfavourable) Expressed in all Expressed in all testis: 32.9 Expressed in all +CUL3 ENSG00000036257 Cullin 3 2 224470150-224585397 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB002678 Supported Expressed in all Expressed in all testis: 403.1 Expressed in all +MYOM2 ENSG00000036448 Myomesin 2 8 2045040-2165552 Predicted intracellular proteins Evidence at protein level HPA001765, HPA005953 Enhanced Approved Mitochondria Mixed Group enriched 19 heart muscle: 197.4;skeletal muscle: 110.2 breast: 8.1 Group enriched 8 HEK 293: 4.8;SCLC-21H: 2.6;U-266/84: 2.0 +OTC ENSG00000036473 Ornithine carbamoyltransferase X 38352545-38421450 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000243, HPA000570 Enhanced Supported Mitochondria Tissue enriched Group enriched 26 duodenum: 114.4;liver: 195.4;small intestine: 96.9 colon: 5.3 Not detected +CYP46A1 CYP46 ENSG00000036530 Cytochrome P450 family 46 subfamily A member 1 14 99684304-99727301 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040702 Uncertain Tissue enriched Tissue enriched 21 cerebral cortex: 64.1 heart muscle: 3.0 Group enriched 5 AF22: 2.4;U-937: 5.4 +ZZZ3 ATAC1, DKFZP564I052 ENSG00000036549 Zinc finger ZZ-type containing 3 1 77562416-77683419 Predicted intracellular proteins Evidence at protein level HPA053663, HPA054913, HPA066197 Uncertain Approved Nucleus
Nucleoli Liver cancer:6.96e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 32.9 Expressed in all +SLC18A1 CGAT, VAT1, VMAT1 ENSG00000036565 Solute carrier family 18 member A1 8 20144855-20183206 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA006877, HPA063797 Enhanced Tissue enhanced Tissue enriched 11 adrenal gland: 32.6 rectum: 3.0 Cell line enriched 9 SH-SY5Y: 70.0 +USP2 UBP41 ENSG00000036672 Ubiquitin specific peptidase 2 11 119355215-119381726 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006777, HPA007222 Approved Supported Plasma membrane
Cytosol Renal cancer:3.09e-11 (favourable) Expressed in all Tissue enhanced testis: 119.4 skeletal muscle: 59.3 Cell line enhanced U-266/70: 43.2 +CASR FHH, GPRC2A, HHC, HHC1, NSHPT ENSG00000036828 Calcium sensing receptor 3 122183683-122291629 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039686, HPA050335 Enhanced Tissue enriched Tissue enriched 58 parathyroid gland: 1441.4 kidney: 24.6 Not detected +TUBG2 ENSG00000037042 Tubulin gamma 2 17 42659305-42667006 Predicted intracellular proteins Evidence at protein level CAB011495 Approved Supported Microtubule organizing center Liver cancer:4.68e-5 (unfavourable), Renal cancer:3.49e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 77.4 Mixed +RPL26L1 RPL26P1 ENSG00000037241 Ribosomal protein L26 like 1 5 172958729-172969771 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA030449 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Head and neck cancer:2.49e-4 (unfavourable) Expressed in all Expressed in all testis: 124.9 Expressed in all +FLT4 PCL, VEGFR3 ENSG00000037280 Fms related tyrosine kinase 4 5 180601506-180649624 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB000099, HPA046519, HPA067906 Approved Enhanced Nuclear speckles
Plasma membrane
Cell Junctions Expressed in all Mixed spleen: 18.3 Cell line enhanced BEWO: 11.8;HEK 293: 14.1;T-47d: 13.7;TIME: 12.7 +NSUN2 FLJ20303, Misu, MRT5, TRM4 ENSG00000037474 NOP2/Sun RNA methyltransferase family member 2 5 6599239-6633291 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037896 Enhanced Supported Nucleus Renal cancer:5.69e-5 (unfavourable) Expressed in all Expressed in all breast: 44.2 Expressed in all +FBXO42 Fbx42, KIAA1332 ENSG00000037637 F-box protein 42 1 16246839-16352454 Predicted intracellular proteins Evidence at protein level HPA025071 Approved Approved Nucleoplasm Liver cancer:3.72e-4 (unfavourable) Expressed in all Expressed in all skin: 29.9 Expressed in all +MFAP3 ENSG00000037749 Microfibrillar associated protein 3 5 154038906-154220478 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015883, HPA049198 Approved Approved Nucleoplasm
Golgi apparatus Cervical cancer:4.28e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 74.8 Expressed in all +MRI1 MGC3207, MRDI, mtnA, Ypr118w ENSG00000037757 Methylthioribose-1-phosphate isomerase 1 19 13764532-13774282 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042744, CAB045988 Approved Supported Nucleoplasm
Nucleoli fibrillar center
Cytosol Expressed in all Expressed in all placenta: 23.1 Mixed +METTL1 C12orf1, TRM8, TRMT8 ENSG00000037897 Methyltransferase like 1 12 57768471-57772793 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020914, HPA050450 Uncertain Enhanced Nucleus Renal cancer:3.55e-6 (unfavourable), Liver cancer:4.25e-6 (unfavourable) Expressed in all Expressed in all epididymis: 22.8 Cell line enriched 6 RH-30: 242.6 +HOXC8 HOX3, HOX3A ENSG00000037965 Homeobox C8 12 54009106-54012362 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028911, CAB037020 Uncertain Approved Nucleoplasm
Microtubules Renal cancer:1.47e-5 (unfavourable) Mixed Tissue enhanced epididymis: 21.1;smooth muscle: 12.6 adrenal gland: 7.7 Cell line enhanced ASC diff: 33.3;fHDF/TERT166: 46.1;HSkMC: 28.1;LHCN-M2: 36.5 +AGA ASRG ENSG00000038002 Aspartylglucosaminidase 4 177430770-177442503 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031415, HPA031417 Enhanced Liver cancer:1.99e-4 (unfavourable), Head and neck cancer:8.61e-4 (unfavourable) Expressed in all Expressed in all epididymis: 35.3 Expressed in all +PI4K2B FLJ11105, PI4KIIB, PIK42B ENSG00000038210 Phosphatidylinositol 4-kinase type 2 beta 4 25233975-25279092 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004099 Approved Supported Cytosol Colorectal cancer:9.64e-5 (favourable) Expressed in all Mixed thyroid gland: 33.9 Expressed in all +BOD1L1 BOD1L, FAM44A, FLJ33215, KIAA1327 ENSG00000038219 Biorientation of chromosomes in cell division 1 like 1 4 13568738-13627723 Predicted intracellular proteins Evidence at protein level HPA036943, HPA037362, HPA041290 Approved Enhanced Nucleoplasm Renal cancer:3.48e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 39.3 Expressed in all +MAT2B MATIIbeta, SDR23E1 ENSG00000038274 Methionine adenosyltransferase 2B 5 163503114-163519336 Predicted intracellular proteins Evidence at protein level HPA037721, HPA037722 Uncertain Renal cancer:4.51e-7 (favourable) Expressed in all Expressed in all thyroid gland: 133.5 Expressed in all +TLL1 ENSG00000038295 Tolloid like 1 4 165873258-166103895 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA060767 Approved Vesicles Mixed Tissue enhanced placenta: 10.5 gallbladder: 4.4 Cell line enhanced HeLa: 4.3;Karpas-707: 7.1;PC-3: 3.3 +EDC4 Ge-1, HEDLS, RCD-8 ENSG00000038358 Enhancer of mRNA decapping 4 16 67873023-67884503 Predicted intracellular proteins Evidence at protein level HPA041164, HPA043038 Supported Enhanced Nucleoplasm
Cytoplasmic bodies Liver cancer:7.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.7 Expressed in all +TRIO ARHGEF23 ENSG00000038382 Trio Rho guanine nucleotide exchange factor 5 14143702-14532128 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008157, HPA064664 Supported Approved Vesicles
Cytosol Renal cancer:3.11e-5 (unfavourable), Endometrial cancer:1.90e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 47.2 Cell line enhanced hTEC/SVTERT24-B: 190.1;U-87 MG: 248.3 +VCAN CSPG2, PG-M ENSG00000038427 Versican 5 83471465-83582303 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004726, CAB008979 Enhanced Supported Vesicles Stomach cancer:1.41e-4 (unfavourable), Renal cancer:5.17e-4 (unfavourable), Melanoma:7.59e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 105.5;placenta: 104.6 smooth muscle: 67.1 Cell line enhanced AF22: 296.8;RPTEC TERT1: 288.7;U-2197: 156.9 +CLEC16A Gop-1, KIAA0350 ENSG00000038532 C-type lectin domain family 16 member A 16 10944488-11182189 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035814, HPA035815, HPA061385 Approved Approved Nucleus
Vesicles Renal cancer:2.92e-6 (favourable) Expressed in all Expressed in all testis: 60.3 Expressed in all +MSR1 CD204, SCARA1 ENSG00000038945 Macrophage scavenger receptor 1 8 16107878-16567490 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000272, CAB032491 Enhanced Expressed in all Tissue enhanced lung: 187.7 gallbladder: 50.2 Group enriched 6 BJ hTERT+: 86.3;REH: 37.8 +CDH1 CD324, UVO, uvomorulin ENSG00000039068 Cadherin 1 16 68737225-68835548 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857 Enhanced Supported Golgi apparatus
Plasma membrane
Cell Junctions Renal cancer:2.06e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 475.1 thyroid gland: 266.2 Cell line enhanced BEWO: 645.6;CAPAN-2: 281.0;HaCaT: 273.9 +SKIV2L2 Dob1, fSAP118, KIAA0052, Mtr4 ENSG00000039123 Ski2 like RNA helicase 2 5 55307760-55425581 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037379 Supported Supported Nucleus Expressed in all Expressed in all parathyroid gland: 37.1 Expressed in all +DNAH5 CILD3, Dnahc5, HL1, KTGNR, PCD ENSG00000039139 Dynein axonemal heavy chain 5 5 13690331-13944543 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037469, HPA037470 Enhanced Tissue enhanced Tissue enhanced fallopian tube: 6.2;lung: 2.6 breast: 2.0 Cell line enhanced BJ hTERT+: 1.3;PC-3: 2.5;RPTEC TERT1: 1.1 +ZFYVE16 KIAA0305, PPP1R69 ENSG00000039319 Zinc finger FYVE-type containing 16 5 80408013-80479350 Predicted intracellular proteins Evidence at protein level HPA035935, HPA035936 Supported Enhanced Vesicles
Cytosol Expressed in all Mixed cervix, uterine: 24.0 Expressed in all +FAM65A FLJ13725 ENSG00000039523 Family with sequence similarity 65 member A 16 67518418-67546788 Predicted intracellular proteins Evidence at protein level HPA005923 Uncertain Approved Golgi apparatus
Cytosol Renal cancer:5.82e-8 (favourable), Lung cancer:5.00e-5 (unfavourable), Head and neck cancer:6.53e-4 (unfavourable) Expressed in all Expressed in all spleen: 59.5 Expressed in all +C6 ENSG00000039537 Complement C6 5 41142234-41261438 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level HPA043823, CAB069427 Enhanced Renal cancer:4.31e-4 (favourable) Group enriched Group enriched 9 fallopian tube: 73.5;liver: 358.3 heart muscle: 23.4 Group enriched 11 ASC diff: 3.2;ASC TERT1: 4.5;HSkMC: 12.3 +RAI14 DKFZp564G013, KIAA1334, NORPEG, RAI13 ENSG00000039560 Retinoic acid induced 14 5 34656237-34832627 Predicted intracellular proteins Evidence at protein level HPA036949, HPA036950 Supported Supported Nucleus
Actin filaments
Cytosol Stomach cancer:2.05e-4 (unfavourable), Renal cancer:9.75e-4 (unfavourable) Expressed in all Mixed endometrium: 92.0 Mixed +SOX30 ENSG00000039600 SRY-box 30 5 157625679-157671480 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006159, CAB009382 Enhanced Mixed Tissue enriched 94 testis: 144.4 fallopian tube: 1.5 Cell line enhanced A-431: 1.7;CACO-2: 1.0;HDLM-2: 3.8 +PNKP PNK ENSG00000039650 Polynucleotide kinase 3'-phosphatase 19 49859882-49878351 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006782 Supported Supported Nucleus
Nucleoli Breast cancer:9.18e-4 (favourable) Expressed in all Expressed in all spleen: 38.1 Expressed in all +BEST2 FLJ20132, VMD2L1 ENSG00000039987 Bestrophin 2 19 12751702-12758458 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level HPA046229 Approved Tissue enhanced Tissue enhanced colon: 15.4;rectum: 14.8 tonsil: 4.5 Mixed +PHLPP2 KIAA0931, PHLPPL, PPM3B ENSG00000040199 PH domain and leucine rich repeat protein phosphatase 2 16 71637835-71724701 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048598 Approved Approved Vesicles Expressed in all Mixed small intestine: 24.2 Expressed in all +SPDL1 CCDC99, FLJ20364, hSpindly ENSG00000040275 Spindle apparatus coiled-coil protein 1 5 169583634-169604778 Predicted intracellular proteins Evidence at protein level HPA044700, HPA048146 Enhanced Approved Cytosol Liver cancer:1.48e-6 (unfavourable), Renal cancer:2.13e-6 (unfavourable), Pancreatic cancer:1.19e-5 (unfavourable), Endometrial cancer:1.18e-4 (unfavourable) Expressed in all Tissue enhanced testis: 60.9 lymph node: 16.4 Expressed in all +STAU2 39K2 ENSG00000040341 Staufen double-stranded RNA binding protein 2 8 73420369-73747708 Predicted intracellular proteins Evidence at protein level HPA019155, CAB020836 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 74.0 Expressed in all +PQLC2 FLJ20320 ENSG00000040487 PQ loop repeat containing 2 1 19312326-19329300 Predicted membrane proteins, Transporters Evidence at protein level HPA057810 Approved Enhanced Vesicles Liver cancer:2.64e-5 (unfavourable), Endometrial cancer:3.50e-4 (favourable) Expressed in all Expressed in all testis: 16.3 Expressed in all +CTNS CTNS-LSB, PQLC4 ENSG00000040531 Cystinosin, lysosomal cystine transporter 17 3636468-3661542 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA046947 Supported Vesicles
Intermediate filaments Pancreatic cancer:6.39e-5 (favourable), Head and neck cancer:7.33e-4 (favourable) Expressed in all Expressed in all testis: 42.6 Expressed in all +RTN4R NOGOR ENSG00000040608 Reticulon 4 receptor 22 20241415-20283246 Predicted membrane proteins Evidence at protein level CAB012443 Supported Plasma membrane
Actin filaments
Focal adhesion sites Head and neck cancer:7.73e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 23.8 spleen: 5.0 Cell line enhanced NB-4: 24.1;REH: 48.8;SCLC-21H: 36.8 +PHF23 FLJ16355, MGC2941 ENSG00000040633 PHD finger protein 23 17 7235028-7239722 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA052410 Approved Enhanced Nucleoplasm Expressed in all Expressed in all testis: 41.7 Expressed in all +CDH10 ENSG00000040731 Cadherin 10 5 24487100-24644978 Predicted membrane proteins Evidence at protein level HPA010651 Approved Group enriched Group enriched 20 cerebral cortex: 32.6;prostate: 7.5 adrenal gland: 1.0 Cell line enhanced AF22: 7.0;HAP1: 4.8;U-138 MG: 1.5 +INPP4A INPP4 ENSG00000040933 Inositol polyphosphate-4-phosphatase type I A 2 98444854-98594390 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001628 Approved Approved Nucleus
Nuclear membrane Endometrial cancer:3.70e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 38.7 Expressed in all +RAB27B ENSG00000041353 RAB27B, member RAS oncogene family 18 54717860-54895516 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017712, HPA019849 Enhanced Uncertain Golgi apparatus
Plasma membrane
Cytosol Pancreatic cancer:2.13e-4 (unfavourable) Mixed Tissue enhanced prostate: 31.7;stomach: 40.5 cerebral cortex: 24.3 Cell line enhanced HEL: 54.6;U-87 MG: 154.0 +PSMA4 HC9, HsT17706 ENSG00000041357 Proteasome subunit alpha 4 15 78540405-78552419 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004973, HPA055466, HPA060613 Supported Enhanced Nucleus
Vesicles
Cytosol Renal cancer:6.74e-10 (unfavourable) Expressed in all Expressed in all testis: 174.1 Expressed in all +MYO16 KIAA0865, Myo16b, MYR8, NYAP3, PPP1R107 ENSG00000041515 Myosin XVI 13 108596152-109208007 Predicted intracellular proteins Evidence at protein level HPA040110, HPA058769, HPA071948 Uncertain Approved Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 2.1 testis: 1.0 Cell line enhanced SH-SY5Y: 2.4;U-2197: 1.2 +LSG1 FLJ11301 ENSG00000041802 Large 60S subunit nuclear export GTPase 1 3 194640788-194672477 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037704, HPA037705 Approved Supported Nucleus
Nuclear bodies
Cytosol Liver cancer:3.21e-7 (unfavourable) Expressed in all Expressed in all testis: 24.8 Expressed in all +PARP3 ADPRT3, ADPRTL3, hPARP-3, IRT1, pADPRT-3 ENSG00000041880 Poly(ADP-ribose) polymerase family member 3 3 51942345-51948867 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA067657 Supported Renal cancer:1.25e-8 (favourable), Breast cancer:6.39e-5 (favourable) Expressed in all Mixed parathyroid gland: 53.0 Expressed in all +TNC DFNA56, HXB, MGC167029, TN ENSG00000041982 Tenascin C 9 115019578-115118257 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB004592, HPA004823 Approved Expressed in all Tissue enhanced appendix: 239.3;smooth muscle: 528.9 adipose tissue: 78.7 Cell line enhanced BJ hTERT+: 628.6;hTEC/SVTERT24-B: 625.8;U-87 MG: 679.1;WM-115: 1198.9 +THAP3 ENSG00000041988 THAP domain containing 3 1 6624866-6635586 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067114 Approved Approved Nucleus Colorectal cancer:1.33e-4 (unfavourable) Expressed in all Expressed in all ovary: 18.0 Expressed in all +FAM65C C20orf175, C20orf176, dJ530I15.2, dJ530I15.3 ENSG00000042062 Family with sequence similarity 65 member C 20 50586108-50691528 Predicted intracellular proteins Evidence at protein level HPA051823, HPA054759 Uncertain Approved Nucleoplasm Head and neck cancer:1.66e-5 (favourable) Mixed Mixed endometrium: 18.2 Cell line enhanced ASC diff: 24.7;HEL: 50.2;HSkMC: 24.1;K-562: 29.7 +TDP1 FLJ11090, SCAN1 ENSG00000042088 Tyrosyl-DNA phosphodiesterase 1 14 89954939-90044768 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA071317 Supported Nucleus
Plasma membrane Liver cancer:8.99e-5 (unfavourable) Expressed in all Mixed testis: 40.6 Expressed in all +AIFM2 AMID, FLJ14497, PRG3 ENSG00000042286 Apoptosis inducing factor, mitochondria associated 2 10 70098223-70132934 Predicted intracellular proteins Evidence at protein level HPA028961, HPA042309 Approved Approved Cytosol Endometrial cancer:2.80e-4 (favourable), Urothelial cancer:2.92e-4 (favourable) Expressed in all Tissue enhanced adipose tissue: 42.7 thyroid gland: 17.9 Cell line enhanced Hep G2: 113.7 +C2orf83 DKFZp547H025 ENSG00000042304 Chromosome 2 open reading frame 83 2 227610090-227633320 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA030319 Approved Not detected Tissue enhanced placenta: 2.9 testis: 0.9 Cell line enhanced U-2197: 1.4 +SPATA7 HSD3, LCA3 ENSG00000042317 Spermatogenesis associated 7 14 88384924-88470350 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038082, HPA038083 Enhanced Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:2.50e-5 (favourable), Pancreatic cancer:4.16e-5 (favourable) Expressed in all Tissue enriched 5 testis: 102.9 thyroid gland: 20.1 Mixed +MED17 CRSP6, CRSP77, DRIP80, TRAP80 ENSG00000042429 Mediator complex subunit 17 11 93784227-93814963 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA064236 Approved Nucleoplasm
Vesicles Liver cancer:4.04e-6 (unfavourable), Breast cancer:4.94e-4 (unfavourable) Expressed in all Mixed spleen: 3.2 Mixed +RETSAT FLJ20296 ENSG00000042445 Retinol saturase 2 85342088-85354620 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007961, HPA046513 Uncertain Approved Nucleoli Renal cancer:1.95e-10 (favourable), Liver cancer:4.23e-4 (favourable) Expressed in all Expressed in all adipose tissue: 265.4 Expressed in all +CAPG AFCP, MCP ENSG00000042493 Capping actin protein, gelsolin like 2 85394748-85418432 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018843, HPA019080, HPA019092 Enhanced Enhanced Nucleus Liver cancer:3.22e-5 (unfavourable), Renal cancer:2.96e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 238.0 Cell line enhanced CAPAN-2: 560.8;HMC-1: 788.5;SK-MEL-30: 524.4 +AP2S1 CLAPS2, FBH3, FBHOk, HHC3 ENSG00000042753 Adaptor related protein complex 2 sigma 1 subunit 19 46838136-46850992 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:1.48e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 114.5 Expressed in all +USH2A RP39, USH2 ENSG00000042781 Usherin 1 215622894-216423396 Disease related genes, Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced liver: 3.6;testis: 1.0 epididymis: 0.7 Not detected +ZPBP SP38, ZPBP1 ENSG00000042813 Zona pellucida binding protein 7 49850421-50121329 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA058673 Enhanced Not detected Tissue enriched 267 testis: 252.9 epididymis: 0.9 Not detected +TG AITD3, TGN ENSG00000042832 Thyroglobulin 8 132866958-133134903 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000077, HPA002740, CAB056155 Enhanced Tissue enriched Tissue enriched 1104 thyroid gland: 15620.0 gallbladder: 14.1 Cell line enhanced HDLM-2: 1.9;Karpas-707: 4.0;PC-3: 2.6 +ADAM28 ADAM23, eMDCII, MDC-Lm, MDC-Ls ENSG00000042980 ADAM metallopeptidase domain 28 8 24294040-24359018 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA074034 Enhanced Approved Plasma membrane
Mitochondria Endometrial cancer:3.17e-4 (favourable) Mixed Tissue enhanced epididymis: 435.5 stomach: 104.6 Cell line enriched 10 CAPAN-2: 24.6 +BARX2 ENSG00000043039 BARX homeobox 2 11 129375940-129452279 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB033311, HPA068414 Enhanced Supported Nucleoplasm
Cytosol Urothelial cancer:3.06e-4 (unfavourable) Mixed Tissue enhanced esophagus: 103.8;salivary gland: 60.3 fallopian tube: 28.0 Cell line enriched 5 HDLM-2: 158.6 +DCUN1D1 DCUN1L1, RP42, SCCRO, SCRO, Tes3 ENSG00000043093 Defective in cullin neddylation 1 domain containing 1 3 182938074-182985953 Predicted intracellular proteins Evidence at protein level HPA035911 Uncertain Approved Nucleus
Cytosol Expressed in all Tissue enriched 13 testis: 391.8 thyroid gland: 29.4 Expressed in all +JADE2 JADE-2, KIAA0239, PHF15 ENSG00000043143 Jade family PHD finger 2 5 134524312-134583230 Enzymes, Predicted intracellular proteins Evidence at protein level HPA025959, HPA055789 Uncertain Enhanced Nucleoplasm Renal cancer:5.36e-6 (favourable), Ovarian cancer:4.42e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 48.6 Mixed +ZIC2 HPE5 ENSG00000043355 Zic family member 2 13 99981772-99986773 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055031 Supported Nuclear bodies Cervical cancer:2.64e-4 (favourable), Liver cancer:2.91e-4 (unfavourable) Mixed Tissue enriched 6 cerebral cortex: 7.3 testis: 1.2 Cell line enhanced AF22: 84.4;HEK 293: 60.2;NTERA-2: 79.9;SCLC-21H: 209.9 +LCP2 SLP-76, SLP76 ENSG00000043462 Lymphocyte cytosolic protein 2 5 170246237-170298227 Predicted intracellular proteins Evidence at protein level CAB004574, HPA036396, HPA036397 Enhanced Renal cancer:6.22e-5 (unfavourable), Endometrial cancer:5.08e-4 (favourable) Expressed in all Expressed in all spleen: 125.5 Cell line enhanced HEL: 149.4;HL-60: 137.8;HMC-1: 372.4;MOLT-4: 84.0;U-937: 87.8 +TRIT1 FLJ20061, IPT ENSG00000043514 TRNA isopentenyltransferase 1 1 39841022-39883511 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024174 Approved Approved Nucleoplasm
Cytosol Renal cancer:7.08e-8 (unfavourable), Liver cancer:5.34e-6 (unfavourable), Endometrial cancer:8.80e-4 (unfavourable) Expressed in all Expressed in all endometrium: 25.1 Expressed in all +ADRB1 ADRB1R ENSG00000043591 Adrenoceptor beta 1 10 114044056-114046908 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA067972 Enhanced Tissue enriched Tissue enhanced placenta: 45.4 heart muscle: 10.8 Cell line enhanced HDLM-2: 6.7;THP-1: 3.2;TIME: 5.0 +GUCA2B ENSG00000044012 Guanylate cyclase activator 2B 1 42153421-42155824 Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced colon: 87.6;small intestine: 148.3 duodenum: 37.5 Group enriched 6 A549: 1.3;CACO-2: 3.2 +CUL7 dJ20C7.5, KIAA0076 ENSG00000044090 Cullin 7 6 43037617-43053945 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015449, HPA030095, HPA030096 Approved Renal cancer:2.19e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 26.3 Expressed in all +CTNNA1 CAP102 ENSG00000044115 Catenin alpha 1 5 138610967-138935034 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB021089, HPA046119, HPA063535 Approved Enhanced Plasma membrane
Cell Junctions Renal cancer:7.34e-7 (favourable), Pancreatic cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 217.1 Mixed +PHKA2 PHK, PYK ENSG00000044446 Phosphorylase kinase regulatory subunit alpha 2 X 18892300-18984598 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA002912 Approved Approved Nucleoplasm Liver cancer:1.25e-5 (unfavourable), Renal cancer:1.55e-5 (unfavourable), Urothelial cancer:2.96e-5 (favourable), Pancreatic cancer:7.68e-4 (favourable) Expressed in all Expressed in all ovary: 18.5 Expressed in all +CNTLN bA340N12.1, C9orf101, C9orf39, FLJ20276 ENSG00000044459 Centlein 9 17134982-17503923 Predicted intracellular proteins Evidence at protein level HPA007201, HPA036728, HPA036729 Uncertain Approved Nucleoplasm
Centrosome
Cytosol Mixed Mixed endometrium: 11.8 Cell line enhanced HEL: 31.6 +EPHA3 ETK, ETK1, HEK, HEK4, TYRO4 ENSG00000044524 EPH receptor A3 3 89107524-89482134 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB010462 Approved Uncertain Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:3.28e-7 (unfavourable) Mixed Tissue enhanced prostate: 51.9 gallbladder: 29.8 Cell line enriched 7 AF22: 192.5 +HSPA5 BiP, GRP78 ENSG00000044574 Heat shock protein family A (Hsp70) member 5 9 125234853-125241330 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB005221, HPA038845, HPA038846 Enhanced Approved Cytosol Renal cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 968.4 Expressed in all +DSG2 CDHF5 ENSG00000046604 Desmoglein 2 18 31498043-31549008 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004896, CAB025122 Enhanced Enhanced Plasma membrane
Cell Junctions Renal cancer:3.14e-10 (favourable), Pancreatic cancer:4.94e-5 (unfavourable), Lung cancer:2.43e-4 (unfavourable), Head and neck cancer:5.63e-4 (unfavourable), Colorectal cancer:7.81e-4 (favourable), Cervical cancer:8.22e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 251.3 rectum: 106.9 Cell line enhanced HaCaT: 233.0;hTERT-HME1: 159.3 +GEMIN8 FAM51A1, FLJ20514 ENSG00000046647 Gem nuclear organelle associated protein 8 X 14008279-14029893 Predicted intracellular proteins Evidence at protein level HPA028613 Uncertain Supported Nucleoplasm
Cytosol Urothelial cancer:7.73e-5 (favourable), Liver cancer:7.78e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 31.7 Expressed in all +OFD1 71-7A, CXorf5, JBTS10, RP23 ENSG00000046651 OFD1, centriole and centriolar satellite protein X 13734745-13769353 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031102, HPA031103, HPA031104 Approved Supported Microtubules Urothelial cancer:2.76e-7 (favourable), Renal cancer:1.63e-4 (unfavourable), Cervical cancer:9.62e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 34.7 Expressed in all +GPM6B M6B, MGC17150, MGC54284 ENSG00000046653 Glycoprotein M6B X 13771031-13938638 Predicted membrane proteins Evidence at protein level HPA002913 Approved Ovarian cancer:2.67e-4 (favourable) Group enriched Tissue enriched 17 cerebral cortex: 835.8 seminal vesicle: 48.6 Cell line enhanced AF22: 147.7;AN3-CA: 138.3;HSkMC: 79.6;SK-MEL-30: 117.9 +MAGEC2 CT10, HCA587, MAGE-C2, MAGEE1 ENSG00000046774 MAGE family member C2 X 142202345-142205290 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA062230 Enhanced Supported Nucleus
Nucleoli
Cytosol Tissue enhanced Tissue enriched 369 testis: 36.8 all non-specific tissues: 0.0 Group enriched 7 K-562: 78.0;U-266/84: 69.6 +PREX2 DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129 ENSG00000046889 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 8 67952118-68237030 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015234, HPA075956 Enhanced Approved Endoplasmic reticulum Renal cancer:1.61e-7 (unfavourable) Mixed Mixed cerebral cortex: 11.9 Cell line enhanced AF22: 13.9;HUVEC TERT2: 16.1;NTERA-2: 12.2;RH-30: 5.3 +WDR37 KIAA0982 ENSG00000047056 WD repeat domain 37 10 1049538-1132297 Predicted intracellular proteins Evidence at protein level HPA037376, HPA037565 Enhanced Uncertain Intermediate filaments
Centrosome
Cytosol Pancreatic cancer:1.46e-6 (favourable), Thyroid cancer:1.34e-5 (unfavourable), Head and neck cancer:1.75e-5 (favourable) Expressed in all Expressed in all testis: 36.4 Expressed in all +YTHDC2 DKFZp564A186, FLJ10053, FLJ2194 ENSG00000047188 YTH domain containing 2 5 113513683-113595285 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037364, HPA072678 Approved Approved Nucleoplasm
Nuclear bodies
Cytoplasmic bodies Colorectal cancer:1.82e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 37.0 Expressed in all +CTPS2 ENSG00000047230 CTP synthase 2 X 16588003-16712936 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017437 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:2.37e-5 (unfavourable), Urothelial cancer:4.56e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.4 Mixed +ATP6V1H CGI-11, SFD, SFDalpha, SFDbeta, VMA13 ENSG00000047249 ATPase H+ transporting V1 subunit H 8 53715557-53843558 Predicted intracellular proteins, Transporters Evidence at protein level CAB009532, HPA023421 Approved Approved Actin filaments
Cytosol Renal cancer:1.46e-7 (favourable), Liver cancer:7.81e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 126.6 Expressed in all +POLR2B RPB2 ENSG00000047315 RNA polymerase II subunit B 4 56977722-57031168 Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA037506 Supported Supported Nucleoplasm Renal cancer:7.17e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 86.2 Expressed in all +FAM214A FLJ10980, KIAA1370 ENSG00000047346 Family with sequence similarity 214 member A 15 52581317-52709817 Predicted intracellular proteins Evidence at protein level HPA039369, HPA040180 Approved Approved Nucleoplasm Endometrial cancer:7.27e-6 (favourable), Lung cancer:8.68e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 57.9 Expressed in all +ARAP2 CENTD1, PARX ENSG00000047365 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 4 35948221-36244509 Predicted intracellular proteins Evidence at protein level HPA035925 Approved Approved Actin filaments
Focal adhesion sites Expressed in all Mixed thyroid gland: 39.1 Mixed +TPR ENSG00000047410 Translocated promoter region, nuclear basket protein 1 186311652-186375693 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA019661, HPA019663, HPA024336 Enhanced Enhanced Nuclear membrane Liver cancer:1.06e-4 (unfavourable), Head and neck cancer:4.71e-4 (favourable) Expressed in all Expressed in all testis: 79.0 Expressed in all +CP ENSG00000047457 Ceruloplasmin 3 149162410-149222055 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001834, CAB008591 Supported Renal cancer:1.14e-7 (unfavourable) Tissue enhanced Tissue enriched 9 liver: 916.0 cervix, uterine: 99.1 Cell line enriched 12 EFO-21: 273.0 +KIAA0556 JBTS26 ENSG00000047578 KIAA0556 16 27550133-27780369 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035089, HPA035090 Enhanced Approved Nuclear speckles
Plasma membrane Head and neck cancer:3.00e-4 (favourable) Expressed in all Tissue enhanced fallopian tube: 47.6 thyroid gland: 26.7 Expressed in all +DTNBP1 BLOC1S8, DBND, Dysbindin, HPS7, My031 ENSG00000047579 Dystrobrevin binding protein 1 6 15522801-15663058 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028053, HPA029615, HPA029616 Enhanced Supported Microtubules
Midbody Lung cancer:6.34e-5 (favourable), Cervical cancer:2.82e-4 (favourable), Liver cancer:8.72e-4 (unfavourable) Expressed in all Expressed in all lymph node: 32.7 Expressed in all +XK Kx, NA, NAC, X1k, XKR1 ENSG00000047597 X-linked Kx blood group X 37685759-37732130 Blood group antigen proteins, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA019036 Approved Approved Nucleoplasm
Vesicles
Mitochondria Mixed Mixed rectum: 12.1 Cell line enhanced HEL: 39.5;K-562: 25.8 +ANO2 C12orf3, TMEM16B ENSG00000047617 Anoctamin 2 12 5531869-5946232 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA036276, HPA057499 Supported Supported Nucleoplasm
Plasma membrane Tissue enhanced Tissue enhanced testis: 17.8 placenta: 5.9 Cell line enhanced BJ hTERT+: 7.8;HUVEC TERT2: 7.9;U-2 OS: 25.6 +C12orf4 ENSG00000047621 Chromosome 12 open reading frame 4 12 4487728-4538508 Predicted intracellular proteins Evidence at protein level HPA037871 Uncertain Approved Nuclear bodies Expressed in all Mixed testis: 16.9 Expressed in all +SCML1 ENSG00000047634 Sex comb on midleg-like 1 (Drosophila) X 17737449-17754988 Predicted intracellular proteins Evidence at protein level HPA035270, HPA035271, HPA061397 Enhanced Approved Nucleus Expressed in all Expressed in all testis: 54.2 Cell line enhanced U-2197: 82.3 +WWC3 BM042, KIAA1280 ENSG00000047644 WWC family member 3 X 10015562-10144478 Predicted intracellular proteins Evidence at protein level HPA039814 Uncertain Approved Actin filaments
Cytosol Renal cancer:1.06e-5 (unfavourable), Colorectal cancer:1.31e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 39.8 Cell line enhanced T-47d: 129.2 +ARHGAP6 rhoGAPX-1 ENSG00000047648 Rho GTPase activating protein 6 X 11137543-11665701 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036779, HPA064390 Enhanced Renal cancer:1.55e-8 (favourable) Tissue enhanced Tissue enhanced prostate: 44.3;seminal vesicle: 43.3 thyroid gland: 42.4 Cell line enhanced ASC TERT1: 23.8;HEL: 32.1;HMC-1: 21.3;HSkMC: 24.5;K-562: 23.6 +FAM184B KIAA1276 ENSG00000047662 Family with sequence similarity 184 member B 4 17629306-17781512 Predicted intracellular proteins Evidence at protein level HPA044119, HPA048458 Enhanced Mixed Group enriched 6 cerebral cortex: 2.6;skeletal muscle: 1.4 kidney,parathyroid gland,skin: 0.3 Cell line enhanced SCLC-21H: 2.5 +MAP4 ENSG00000047849 Microtubule associated protein 4 3 47850690-48089272 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038149, HPA038150 Enhanced Supported Plasma membrane
Microtubules
Cytosol Liver cancer:1.82e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 241.9 Expressed in all +GOPC CAL, dJ94G16.2, FIG, GOPC1, PIST ENSG00000047932 Golgi associated PDZ and coiled-coil motif containing 6 117560269-117602542 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019477, HPA024018 Approved Enhanced Golgi apparatus
Cytosol Expressed in all Expressed in all parathyroid gland: 47.9 Expressed in all +ROS1 c-ros-1, MCF3, ROS ENSG00000047936 ROS proto-oncogene 1, receptor tyrosine kinase 6 117288300-117425855 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049098, HPA072424 Uncertain Approved Vesicles Tissue enriched Group enriched 18 epididymis: 70.9;lung: 47.2 seminal vesicle: 3.2 Cell line enhanced HSkMC: 7.5;hTCEpi: 15.7;LHCN-M2: 12.7 +USP28 KIAA1515 ENSG00000048028 Ubiquitin specific peptidase 28 11 113797874-113875570 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006778, HPA006779 Enhanced Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all heart muscle: 40.2 Expressed in all +HDAC9 HD7, HDAC, HDAC7B, KIAA0744, MITR ENSG00000048052 Histone deacetylase 9 7 18086949-19002416 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028926 Uncertain Approved Nucleoplasm Mixed Mixed spleen: 24.6 Cell line enhanced HAP1: 176.1;SH-SY5Y: 71.2 +TSPAN17 FBX23, FBXO23, TM4SF17 ENSG00000048140 Tetraspanin 17 5 176647387-176659054 Predicted membrane proteins Evidence at transcript level HPA030447 Approved Nucleoplasm Expressed in all Expressed in all bone marrow: 34.7 Expressed in all +NOP16 HSPC111, HSPC185, LOC51491 ENSG00000048162 NOP16 nucleolar protein 5 176383938-176388975 Predicted intracellular proteins Evidence at protein level HPA036506, HPA058147 Approved Enhanced Nucleoli Renal cancer:5.75e-6 (unfavourable), Liver cancer:5.14e-4 (unfavourable) Expressed in all Expressed in all appendix: 26.1 Expressed in all +CC2D2A JBTS9, KIAA1345, MKS6 ENSG00000048342 Coiled-coil and C2 domain containing 2A 4 15469865-15601557 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044124 Approved Renal cancer:3.42e-9 (favourable), Stomach cancer:4.43e-4 (unfavourable) Expressed in all Tissue enhanced fallopian tube: 53.9 kidney: 20.8 Mixed +RRM2B p53R2 ENSG00000048392 Ribonucleotide reductase regulatory TP53 inducible subunit M2B 8 102204502-102239118 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB006854, HPA028812 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 75.1 Expressed in all +ZNF800 ENSG00000048405 Zinc finger protein 800 7 127346790-127431924 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023090, HPA052194 Approved Supported Nucleoli
Cytosol Expressed in all Expressed in all bone marrow: 47.9 Expressed in all +TNFRSF17 BCM, BCMA, CD269, TNFRSF13A ENSG00000048462 TNF receptor superfamily member 17 16 11965107-11968068 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Head and neck cancer:1.58e-6 (favourable), Breast cancer:1.35e-5 (favourable) Mixed Tissue enhanced tonsil: 36.7 lymph node: 30.8 Group enriched 7 Karpas-707: 114.0;RPMI-8226: 179.8;U-266/70: 561.8;U-266/84: 274.9 +SNX29 FLJ12363, RUNDC2A ENSG00000048471 Sorting nexin 29 16 11976737-12574289 Predicted intracellular proteins Evidence at protein level HPA008889 Approved Renal cancer:1.38e-7 (favourable), Urothelial cancer:1.03e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 39.7 Mixed +LMO3 DAT1, RBTNL2, Rhom-3 ENSG00000048540 LIM domain only 3 12 16548373-16610594 Predicted intracellular proteins Evidence at protein level Endometrial cancer:1.10e-7 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 190.9 thyroid gland: 67.7 Group enriched 6 ASC diff: 157.0;LHCN-M2: 88.8 +MRPS10 FLJ10567 ENSG00000048544 Mitochondrial ribosomal protein S10 6 42206801-42217865 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA029133, HPA029134 Enhanced Approved Actin filaments
Mitochondria Expressed in all Expressed in all esophagus: 41.8 Expressed in all +GUCA1A C6orf131, COD3, CORD14, dJ139D8.6, GCAP, GCAP1, GUCA, GUCA1 ENSG00000048545 Guanylate cyclase activator 1A 6 42155406-42180056 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005561 Supported Approved Uncertain Plasma membrane Tissue enriched Tissue enriched 19 testis: 30.0 cerebral cortex: 1.5 Group enriched 8 NTERA-2: 3.6;SH-SY5Y: 4.7 +RSF1 HBXAP, p325, RSF-1, XAP8 ENSG00000048649 Remodeling and spacing factor 1 11 77659996-77821017 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB022626, HPA046129, HPA057547, HPA064567 Enhanced Enhanced Nucleoplasm Pancreatic cancer:1.61e-4 (unfavourable), Renal cancer:5.94e-4 (favourable) Expressed in all Expressed in all testis: 44.2 Expressed in all +VPS13D FLJ10619, KIAA0453 ENSG00000048707 Vacuolar protein sorting 13 homolog D 1 12230067-12512047 Predicted intracellular proteins Evidence at protein level HPA027332, HPA051621 Uncertain Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:7.42e-12 (favourable) Expressed in all Expressed in all parathyroid gland: 29.5 Expressed in all +CELF2 BRUNOL3, CUGBP2, Etr-3, NAPOR-2 ENSG00000048740 CUGBP Elav-like family member 2 10 10798397-11336675 Predicted intracellular proteins Evidence at protein level CAB016395, HPA035813, HPA065098 Enhanced Uncertain Nucleoplasm
Microtubules
Cytokinetic bridge Head and neck cancer:7.61e-4 (favourable) Expressed in all Mixed cerebral cortex: 77.8 Cell line enhanced HEL: 179.2;HMC-1: 163.9 +FAM120A C9orf10, KIAA0183, OSSA ENSG00000048828 Family with sequence similarity 120A 9 93451722-93566107 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019734, HPA055800 Approved Enhanced Cytosol Renal cancer:1.08e-7 (favourable), Endometrial cancer:5.03e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 167.1 Expressed in all +R3HDM1 KIAA0029, R3HDM ENSG00000048991 R3H domain containing 1 2 135531455-135725270 Predicted intracellular proteins Evidence at protein level HPA030936 Approved Nucleoplasm
Cytosol Renal cancer:5.83e-7 (unfavourable), Lung cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 82.3 Expressed in all +COL9A2 EDM2, MED ENSG00000049089 Collagen type IX alpha 2 chain 1 40300487-40317816 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA056316, HPA075286 Approved Approved Nucleus
Vesicles Endometrial cancer:5.13e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 53.4 seminal vesicle: 32.4 Cell line enhanced HDLM-2: 91.5;HMC-1: 79.4;THP-1: 69.5 +KITLG FPH2, Kitl, KL-1, MGF, SCF, SF ENSG00000049130 KIT ligand 12 88492793-88580851 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level HPA070395 Approved Approved Vesicles Renal cancer:5.81e-7 (favourable), Liver cancer:4.01e-4 (unfavourable) Expressed in all Mixed lung: 23.5 Cell line enhanced CACO-2: 199.5 +ERCC8 CKN1, CSA ENSG00000049167 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 5 60873831-60945073 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029328 Approved Nuclear speckles Expressed in all Mixed testis: 12.9 Expressed in all +ADAMTS6 ADAM-TS6 ENSG00000049192 ADAM metallopeptidase with thrombospondin type 1 motif 6 5 65148736-65481920 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA043441 Enhanced Mixed Tissue enhanced placenta: 2.7 gallbladder: 2.3 Cell line enhanced HBF TERT88: 13.0;hTEC/SVTERT24-B: 12.5;TIME: 11.8;U-2197: 15.1 +H6PD GDH ENSG00000049239 Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase 1 9234775-9271337 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA004824, HPA005440 Approved Uncertain Cytosol Expressed in all Expressed in all ovary: 42.8 Mixed +VAMP3 CEB ENSG00000049245 Vesicle associated membrane protein 3 1 7771269-7781432 Cancer-related genes, Predicted membrane proteins Evidence at protein level Renal cancer:2.36e-4 (favourable) Expressed in all Expressed in all lung: 135.3 Expressed in all +PER3 ENSG00000049246 Period circadian clock 3 1 7784320-7845177 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019530 Approved Uncertain Cytosol Renal cancer:2.20e-5 (favourable), Head and neck cancer:1.34e-4 (favourable), Cervical cancer:7.14e-4 (favourable) Expressed in all Mixed thyroid gland: 39.2 Mixed +UTS2 PRO1068, U-II, UCN2, UII ENSG00000049247 Urotensin 2 1 7843083-7853512 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017000 Uncertain Mixed Tissue enhanced adrenal gland: 3.9 bone marrow,lymph node: 1.9 Group enriched 17 CACO-2: 17.2;HEL: 6.6;HMC-1: 5.3;THP-1: 17.9 +TNFRSF9 4-1BB, CD137, ILA ENSG00000049249 TNF receptor superfamily member 9 1 7915894-7943165 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level HPA071425 Approved Nucleoli
Plasma membrane Renal cancer:2.69e-8 (unfavourable) Mixed Tissue enhanced lymph node: 11.1;tonsil: 7.0 appendix: 5.2 Cell line enriched 8 HDLM-2: 92.4 +EPN3 FLJ20778, MGC129899 ENSG00000049283 Epsin 3 17 50532543-50543750 Predicted intracellular proteins Evidence at protein level HPA055546, HPA063224 Approved Supported Nucleoplasm
Vesicles Renal cancer:1.53e-5 (favourable) Mixed Mixed stomach: 27.5 Cell line enhanced HaCaT: 24.3;HBEC3-KT: 27.4;MCF7: 48.0;RT4: 38.6;T-47d: 51.4 +LTBP1 ENSG00000049323 Latent transforming growth factor beta binding protein 1 2 32946972-33399509 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005707, CAB025428 Approved Approved Cytosol Renal cancer:7.79e-6 (unfavourable), Urothelial cancer:1.62e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 261.1 Cell line enhanced ASC TERT1: 399.0;U-87 MG: 250.3 +RCN1 FLJ37041, PIG20, Rcal, RCN ENSG00000049449 Reticulocalbin 1 11 31812391-32105755 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038474, HPA062104 Approved Enhanced Endoplasmic reticulum Renal cancer:2.70e-13 (unfavourable), Lung cancer:7.13e-6 (unfavourable) Expressed in all Expressed in all epididymis: 470.5 Mixed +ELN SVAS, WBS, WS ENSG00000049540 Elastin 7 74027789-74069907 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB010750, HPA018111, HPA056941 Supported Approved Plasma membrane Thyroid cancer:6.29e-4 (unfavourable) Expressed in all Mixed smooth muscle: 125.8 Cell line enhanced BJ: 121.3;fHDF/TERT166: 160.9;U-2197: 748.2 +RFC2 A1, RFC40 ENSG00000049541 Replication factor C subunit 2 7 74231499-74254458 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029493 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:2.09e-7 (unfavourable), Liver cancer:6.35e-4 (unfavourable), Cervical cancer:9.91e-4 (favourable) Expressed in all Expressed in all tonsil: 28.1 Expressed in all +ARID1B 6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R ENSG00000049618 AT-rich interaction domain 1B 6 156777374-157210779 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016511, HPA075291 Approved Supported Nucleoplasm Breast cancer:1.04e-4 (unfavourable), Ovarian cancer:4.16e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 71.2 Expressed in all +CLPTM1L CRR9, FLJ14400 ENSG00000049656 CLPTM1 like 5 1317744-1345099 Predicted membrane proteins Evidence at protein level HPA014791 Approved Approved Endoplasmic reticulum Liver cancer:3.75e-4 (unfavourable) Expressed in all Expressed in all testis: 54.1 Expressed in all +NEDD4L KIAA0439, NEDD4-2, RSP5 ENSG00000049759 Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 18 58044367-58401540 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA024618, HPA064730 Approved Approved Focal adhesion sites Renal cancer:6.55e-15 (favourable) Expressed in all Expressed in all prostate: 71.5 Mixed +FOXP3 AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID ENSG00000049768 Forkhead box P3 X 49250436-49264826 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026301, HPA045943 Enhanced Supported Nucleoplasm Cervical cancer:1.91e-4 (favourable), Head and neck cancer:4.90e-4 (favourable), Endometrial cancer:7.02e-4 (favourable) Mixed Tissue enhanced appendix: 8.7 lymph node: 6.0 Cell line enhanced MCF7: 2.8;SiHa: 2.3 +PPP1R3F Hb2E ENSG00000049769 Protein phosphatase 1 regulatory subunit 3F X 49269843-49301461 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000244, HPA000918 Approved Approved Nucleoplasm Pancreatic cancer:1.85e-6 (favourable) Expressed in all Tissue enhanced cerebral cortex: 26.8 epididymis: 14.6 Mixed +HEXB ENSG00000049860 Hexosaminidase subunit beta 5 74640023-74722647 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA055409, HPA056010 Enhanced Liver cancer:3.36e-8 (unfavourable) Expressed in all Expressed in all placenta: 440.8 Mixed +PTCD2 FLJ12598 ENSG00000049883 Pentatricopeptide repeat domain 2 5 72320367-72368395 Predicted intracellular proteins Evidence at protein level HPA043686 Approved Expressed in all Mixed parathyroid gland: 6.9 Expressed in all +KIAA2022 KIDLIA, MRX98, XPN ENSG00000050030 KIAA2022 X 74732849-74925485 Disease related genes, Predicted intracellular proteins Evidence at transcript level HPA000407 Uncertain Uncertain Nucleoplasm
Midbody Mixed Tissue enhanced cerebral cortex: 5.4;parathyroid gland: 5.3 prostate: 1.9 Group enriched 6 HAP1: 5.0;Karpas-707: 5.9;SiHa: 6.2 +JKAMP C14orf100, CDA06, HSPC213, HSPC327, JAMP ENSG00000050130 JNK1/MAPK8-associated membrane protein 14 59484443-59505410 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA031172, HPA071650 Supported Approved Nucleoplasm
Vesicles Liver cancer:3.09e-6 (unfavourable), Renal cancer:1.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 76.2 Expressed in all +DKK3 REIC, RIG ENSG00000050165 Dickkopf WNT signaling pathway inhibitor 3 11 11963106-12009769 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA011868, CAB024949 Approved Approved Vesicles Renal cancer:6.31e-5 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 373.5;heart muscle: 805.5 cervix, uterine: 138.8 Cell line enhanced BJ: 355.1;BJ hTERT+: 524.6;fHDF/TERT166: 475.8;TIME: 285.3 +ARHGEF5 GEF5, P60, TIM, TIM1 ENSG00000050327 Rho guanine nucleotide exchange factor 5 7 144355288-144380632 Predicted intracellular proteins Evidence at protein level HPA020980, HPA029504, HPA044188, HPA045619, HPA045699 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:3.28e-7 (favourable) Mixed Mixed thyroid gland: 42.8 Cell line enhanced A-431: 46.6 +NFE2L3 Nrf3 ENSG00000050344 Nuclear factor, erythroid 2 like 3 7 26152240-26187125 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA055889 Enhanced Approved Nucleoplasm
Vesicles Renal cancer:7.58e-12 (unfavourable), Pancreatic cancer:6.62e-5 (unfavourable), Stomach cancer:2.14e-4 (favourable) Expressed in all Tissue enhanced placenta: 50.3 appendix: 14.3 Cell line enhanced BEWO: 132.0;NTERA-2: 115.5 +MCUR1 C6orf79, CCDC90A, FLJ20958 ENSG00000050393 Mitochondrial calcium uniporter regulator 1 6 13786557-13814568 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:3.32e-4 (favourable), Ovarian cancer:5.51e-4 (favourable) Expressed in all Expressed in all thyroid gland: 26.9 Expressed in all +LIMA1 EPLIN ENSG00000050405 LIM domain and actin binding 1 12 50175788-50283546 Predicted intracellular proteins Evidence at protein level HPA023871, HPA052645 Enhanced Enhanced Plasma membrane
Actin filaments
Focal adhesion sites
Cytosol Head and neck cancer:1.76e-6 (unfavourable), Renal cancer:2.79e-4 (favourable) Expressed in all Expressed in all rectum: 143.8 Expressed in all +LETMD1 HCCR, HCCR-1, HCCR-2, HCCR1, HCCR2 ENSG00000050426 LETM1 domain containing 1 12 51047962-51060424 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA074361 Supported Nucleoplasm
Mitochondria Urothelial cancer:3.16e-4 (favourable), Renal cancer:3.26e-4 (favourable) Expressed in all Expressed in all thyroid gland: 61.7 Expressed in all +SLC4A8 NBC3 ENSG00000050438 Solute carrier family 4 member 8 12 51391317-51515763 Predicted membrane proteins Evidence at protein level HPA031536 Uncertain Actin filaments Group enriched Tissue enhanced cerebral cortex: 14.5;testis: 15.4 ovary: 4.2 Cell line enhanced BEWO: 20.3;SCLC-21H: 18.5 +LAMC3 DKFZp434E202 ENSG00000050555 Laminin subunit gamma 3 9 131009082-131094473 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA022814 Enhanced Mixed Tissue enhanced placenta: 88.7 testis: 26.1 Cell line enhanced AF22: 5.3;EFO-21: 19.9;Hep G2: 5.5;SiHa: 8.5;U-2 OS: 6.9 +PTGER3 EP3 ENSG00000050628 Prostaglandin E receptor 3 1 70852353-71047808 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA010689 Uncertain Renal cancer:3.50e-4 (unfavourable) Group enriched Group enriched 7 adipose tissue: 58.6;endometrium: 115.3;kidney: 88.3;smooth muscle: 105.2 skin: 13.9 Group enriched 5 ASC diff: 19.6;HAP1: 21.6;HDLM-2: 30.4;HEL: 14.0;T-47d: 68.0 +TNIP3 ABIN-3, FLJ21162, LIND ENSG00000050730 TNFAIP3 interacting protein 3 4 121131408-121227466 Predicted intracellular proteins Evidence at protein level HPA043063 Uncertain Mixed Tissue enhanced appendix: 8.8 lymph node,tonsil: 2.9 Cell line enhanced HDLM-2: 6.8;hTEC/SVTERT24-B: 8.0;U-138 MG: 30.3;U-266/70: 6.7;U-266/84: 6.5 +MAPK9 JNK2, p54a, PRKM9, SAPK ENSG00000050748 Mitogen-activated protein kinase 9 5 180233143-180292099 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB008910 Approved Colorectal cancer:1.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 83.9 Expressed in all +COL23A1 DKFZp434K0621 ENSG00000050767 Collagen type XXIII alpha 1 chain 5 178237618-178590555 Predicted intracellular proteins Evidence at protein level HPA067824 Uncertain Endometrial cancer:6.46e-5 (unfavourable) Tissue enhanced Tissue enhanced thyroid gland: 57.8 seminal vesicle: 16.2 Group enriched 8 AF22: 5.7;K-562: 10.8;NB-4: 20.8;THP-1: 22.5 +BCAR1 CAS, CASS1, Crkas, P130Cas ENSG00000050820 BCAR1, Cas family scaffolding protein 16 75228187-75268053 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000443, HPA042282 Approved Supported Approved Plasma membrane
Cytosol Renal cancer:4.55e-8 (favourable), Liver cancer:9.11e-5 (unfavourable), Lung cancer:1.24e-4 (unfavourable) Expressed in all Mixed spleen: 41.0 Mixed +FAM160A2 C11orf56, DKFZP566M1046, FHIP, FLJ22665, KIAA1759 ENSG00000051009 Family with sequence similarity 160 member A2 11 6211335-6234711 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055994, HPA063987 Approved Approved Mitochondria Expressed in all Expressed in all testis: 42.0 Expressed in all +HERPUD1 HERP, KIAA0025, Mif1, SUP ENSG00000051108 Homocysteine inducible ER protein with ubiquitin like domain 1 16 56932048-56944863 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB037041, CAB037104, HPA040754, HPA041219 Approved Uncertain Plasma membrane
Cytosol Renal cancer:1.41e-9 (favourable) Expressed in all Expressed in all thyroid gland: 358.8 Expressed in all +HOMER3 HOMER-3 ENSG00000051128 Homer scaffolding protein 3 19 18929201-18941261 Predicted intracellular proteins Evidence at protein level CAB032656, HPA040999, CAB079015 Enhanced Supported Supported Plasma membrane
Cytosol
Cytoplasmic bodies Colorectal cancer:4.24e-5 (unfavourable), Liver cancer:4.93e-5 (unfavourable) Expressed in all Expressed in all spleen: 150.5 Mixed +RAD51 BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA ENSG00000051180 RAD51 recombinase 15 40694774-40732339 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB010381, HPA039310 Enhanced Enhanced Nucleoli
Mitochondria
Cytosol Breast cancer:7.94e-4 (unfavourable), Liver cancer:9.33e-4 (unfavourable) Expressed in all Tissue enhanced testis: 45.4 lymph node: 13.0 Mixed +POLQ POLH ENSG00000051341 DNA polymerase theta 3 121431427-121546641 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048931, HPA053359 Uncertain Nucleus
Golgi apparatus
Cytosol Endometrial cancer:5.46e-5 (unfavourable), Stomach cancer:1.04e-4 (favourable) Mixed Mixed testis: 4.0 Mixed +PIK3CB PIK3C1 ENSG00000051382 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 3 138652699-138834938 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB031938, HPA064207 Approved Approved Nucleoplasm
Nucleoli
Midbody Pancreatic cancer:3.99e-5 (unfavourable), Liver cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 88.9 Expressed in all +CYBA p22-PHOX ENSG00000051523 Cytochrome b-245 alpha chain 16 88643283-88651152 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB009492 Enhanced Endometrial cancer:4.75e-5 (favourable), Renal cancer:1.83e-4 (unfavourable), Breast cancer:8.19e-4 (favourable) Expressed in all Expressed in all spleen: 466.1 Cell line enhanced RPMI-8226: 1035.0 +THOC3 MGC5469, TEX1 ENSG00000051596 THO complex 3 5 175917873-176034680 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042764, HPA044009, HPA045071 Approved Enhanced Nucleoplasm Expressed in all Expressed in all epididymis: 77.2 Expressed in all +HEBP2 C6orf34, SOUL ENSG00000051620 Heme binding protein 2 6 138403531-138422197 Predicted intracellular proteins Evidence at protein level HPA016928 Approved Renal cancer:2.47e-5 (unfavourable), Urothelial cancer:3.07e-4 (favourable) Expressed in all Expressed in all adipose tissue: 114.1 Cell line enhanced THP-1: 147.3 +MPHOSPH9 MPP9 ENSG00000051825 M-phase phosphoprotein 9 12 123152320-123244014 Predicted intracellular proteins Evidence at protein level HPA037485 Approved Uncertain Nucleus
Plasma membrane
Cytosol Expressed in all Mixed testis: 22.7 Expressed in all +PLEKHA5 FLJ10667, KIAA1686, PEPP2 ENSG00000052126 Pleckstrin homology domain containing A5 12 19129752-19376400 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035923, HPA035924, HPA041455 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:5.41e-5 (unfavourable), Renal cancer:7.42e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 55.1 Cell line enhanced HDLM-2: 61.6;NTERA-2: 64.9 +PRSS8 ENSG00000052344 Protease, serine 8 16 31131433-31135762 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA030436, HPA063533 Uncertain Uncertain Cytosol Renal cancer:2.05e-10 (favourable) Mixed Mixed small intestine: 164.8 Cell line enhanced BEWO: 230.2;CACO-2: 133.7;CAPAN-2: 96.1;hTCEpi: 111.3;SK-BR-3: 136.6 +SIKE1 FLJ21168, SIKE ENSG00000052723 Suppressor of IKBKE 1 1 114769479-114780685 Predicted intracellular proteins Evidence at protein level HPA024177, HPA025726 Supported Approved Vesicles
Focal adhesion sites Expressed in all Expressed in all thyroid gland: 19.4 Expressed in all +RRP12 KIAA0690 ENSG00000052749 Ribosomal RNA processing 12 homolog 10 97356358-97426076 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049945 Supported Nucleoli Liver cancer:3.12e-8 (unfavourable), Renal cancer:2.54e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 58.2 Expressed in all +FNIP2 FNIPL, KIAA1450, MAPO1 ENSG00000052795 Folliculin interacting protein 2 4 158769138-158908049 Predicted intracellular proteins Evidence at protein level HPA042779, HPA072420 Approved Renal cancer:3.96e-11 (favourable) Expressed in all Expressed in all kidney: 51.2 Cell line enhanced HDLM-2: 167.0 +MSMO1 DESP4, ERG25, SC4MOL ENSG00000052802 Methylsterol monooxygenase 1 4 165327623-165343160 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA056127 Approved Cervical cancer:2.97e-4 (unfavourable), Renal cancer:9.21e-4 (favourable) Expressed in all Expressed in all liver: 297.1 Expressed in all +TTC17 FLJ10890 ENSG00000052841 Tetratricopeptide repeat domain 17 11 43358932-43494933 Predicted intracellular proteins Evidence at protein level HPA038508 Approved Supported Plasma membrane
Cytosol Renal cancer:4.75e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 61.8 Expressed in all +ALX4 FPP, KIAA1788, PFM, PFM2 ENSG00000052850 ALX homeobox 4 11 44260444-44310166 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001903 Supported Nucleoplasm Tissue enhanced Tissue enhanced breast: 2.2 endometrium,testis: 1.0 Cell line enhanced AN3-CA: 3.7;BJ: 2.8;HAP1: 4.8;HEK 293: 4.4;HEL: 6.0;K-562: 2.8;SiHa: 7.4 +FSTL4 KIAA1061 ENSG00000053108 Follistatin like 4 5 133196455-133612564 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045920 Uncertain Approved Mitochondria Mixed Tissue enhanced cerebral cortex: 9.5 urinary bladder: 7.3 Cell line enhanced SCLC-21H: 66.8 +FOXN3 C14orf116, CHES1 ENSG00000053254 Forkhead box N3 14 89124871-89619149 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059209 Approved Approved Nucleus
Plasma membrane Renal cancer:9.58e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 111.0 Mixed +METTL24 C6orf186, dJ71D21.2 ENSG00000053328 Methyltransferase like 24 6 110245928-110358272 Predicted secreted proteins Evidence at transcript level HPA037441, HPA037442 Uncertain Mixed Tissue enhanced smooth muscle: 20.5 endometrium: 12.7 Cell line enhanced SCLC-21H: 1.8;SH-SY5Y: 1.0 +AKR7A2 AFAR ENSG00000053371 Aldo-keto reductase family 7 member A2 1 19303965-19312146 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032587, CAB032841, HPA064638 Enhanced Supported Cytosol Renal cancer:2.67e-4 (favourable), Urothelial cancer:8.59e-4 (unfavourable) Expressed in all Expressed in all duodenum: 81.9 Expressed in all +MRTO4 C1orf33, dJ657E11.4, MRT4 ENSG00000053372 MRT4 homolog, ribosome maturation factor 1 19251539-19260128 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA026446 Approved Approved Nucleus
Nuclear membrane
Nucleoli Liver cancer:1.56e-8 (unfavourable), Renal cancer:4.11e-8 (unfavourable) Expressed in all Expressed in all fallopian tube: 25.7 Expressed in all +NNAT Peg5 ENSG00000053438 Neuronatin 20 37521215-37523693 Predicted membrane proteins Evidence at transcript level Group enriched Group enriched 5 cerebral cortex: 157.6;placenta: 147.3 adipose tissue: 27.9 Cell line enriched 28 SH-SY5Y: 735.9 +USE1 D12, MDS032, p31, SLT1 ENSG00000053501 Unconventional SNARE in the ER 1 19 17215346-17219829 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026851, HPA047562 Approved Renal cancer:3.59e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 41.9 Expressed in all +MCF2L2 ARHGEF22, KIAA0861 ENSG00000053524 MCF.2 cell line derived transforming sequence-like 2 3 183178043-183428778 Disease related genes, Predicted intracellular proteins Evidence at transcript level HPA038946, HPA038947 Uncertain Approved Plasma membrane
Cytosol Not detected Group enriched 8 adrenal gland: 10.2;cerebral cortex: 17.2;parathyroid gland: 7.7;spleen: 3.5;testis: 4.7 prostate: 1.0 Cell line enhanced HDLM-2: 5.5;Karpas-707: 3.6;REH: 3.1 +NRIP2 DKFZP761G1913 ENSG00000053702 Nuclear receptor interacting protein 2 12 2825348-2835544 Predicted intracellular proteins Evidence at protein level HPA039197, HPA039860 Enhanced Approved Nucleus
Nuclear bodies
Cytosol Pancreatic cancer:8.69e-5 (favourable), Colorectal cancer:8.05e-4 (unfavourable) Expressed in all Mixed endometrium: 12.4 Mixed +LAMA3 BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa ENSG00000053747 Laminin subunit alpha 3 18 23689443-23955066 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA009309, CAB010757 Uncertain Enhanced Endoplasmic reticulum Pancreatic cancer:3.58e-6 (unfavourable) Mixed Mixed placenta: 30.7 Cell line enhanced CAPAN-2: 122.4;HaCaT: 195.1;HBEC3-KT: 770.3 +AP5M1 C14orf108, FLJ10813, mu5, MuD, MUDENG ENSG00000053770 Adaptor related protein complex 5 mu 1 subunit 14 57268909-57298742 Predicted intracellular proteins Evidence at protein level HPA055768, HPA057098 Approved Renal cancer:1.11e-14 (favourable), Colorectal cancer:7.91e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 43.3 Expressed in all +ANAPC4 APC4 ENSG00000053900 Anaphase promoting complex subunit 4 4 25377213-25418498 Predicted intracellular proteins Evidence at protein level CAB032519, HPA038395, HPA038396 Approved Approved Intermediate filaments Endometrial cancer:5.73e-7 (favourable), Urothelial cancer:1.12e-6 (favourable), Renal cancer:1.17e-5 (unfavourable), Head and neck cancer:1.95e-4 (favourable) Expressed in all Expressed in all fallopian tube: 55.2 Expressed in all +KCNQ1 JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1 ENSG00000053918 Potassium voltage-gated channel subfamily Q member 1 11 2444684-2849109 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB018656, HPA048553 Enhanced Stomach cancer:9.85e-4 (favourable) Expressed in all Tissue enhanced adrenal gland: 133.6;thyroid gland: 102.7 seminal vesicle: 60.6 Cell line enhanced HMC-1: 25.7;RPMI-8226: 14.2;U-266/70: 8.9;U-937: 8.8 +TRAPPC3 BET3 ENSG00000054116 Trafficking protein particle complex 3 1 36136570-36156053 Predicted intracellular proteins Evidence at protein level HPA028408 Approved Approved Golgi apparatus
Cytosol Liver cancer:2.70e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 102.1 Expressed in all +THRAP3 TRAP150 ENSG00000054118 Thyroid hormone receptor associated protein 3 1 36224416-36305357 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012041, CAB017472, HPA063765 Supported Enhanced Nuclear speckles Stomach cancer:5.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 99.0 Expressed in all +PHPT1 bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14 ENSG00000054148 Phosphohistidine phosphatase 1 9 136848724-136851027 Enzymes, Predicted intracellular proteins Evidence at protein level CAB013584, HPA020952 Approved Approved Nuclear bodies
Cytosol Expressed in all Expressed in all heart muscle: 73.8 Expressed in all +ENTPD2 CD39L1, NTPDase-2 ENSG00000054179 Ectonucleoside triphosphate diphosphohydrolase 2 9 137048098-137054045 Predicted membrane proteins Evidence at protein level HPA017676 Approved Renal cancer:3.51e-6 (favourable), Liver cancer:2.48e-5 (unfavourable), Stomach cancer:1.38e-4 (favourable) Expressed in all Mixed duodenum: 12.2 Cell line enhanced Hep G2: 16.3;hTCEpi: 9.2;MCF7: 12.8;SK-BR-3: 16.1;T-47d: 22.0 +LY75 CD205, CLEC13B, DEC-205 ENSG00000054219 Lymphocyte antigen 75 2 159803355-159904749 CD markers, Predicted membrane proteins Evidence at protein level CAB001450, HPA049108, HPA054073 Enhanced Approved Golgi apparatus Renal cancer:2.39e-5 (unfavourable), Urothelial cancer:3.86e-4 (favourable) Mixed Mixed lymph node: 35.5 Cell line enhanced CAPAN-2: 19.4;HDLM-2: 19.8;Karpas-707: 62.7;RT4: 24.1 +ARID4B BCAA, BRCAA1, RBP1L1, SAP180 ENSG00000054267 AT-rich interaction domain 4B 1 235131634-235328219 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027333, HPA053692 Approved Approved Nucleoplasm
Vesicles Renal cancer:2.23e-4 (unfavourable) Expressed in all Expressed in all testis: 32.0 Expressed in all +OPN3 ECPN, encephalopsin, ERO, NMO-1, PPP1R116 ENSG00000054277 Opsin 3 1 241590102-241677376 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB013682, HPA064443 Uncertain Approved Nucleoplasm Cervical cancer:3.17e-5 (unfavourable), Glioma:2.51e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 26.9 lung: 12.8 Cell line enhanced ASC TERT1: 51.2 +SDCCAG8 BBS16, CCCAP, NPHP10, NY-CO-8, SLSN7 ENSG00000054282 Serologically defined colon cancer antigen 8 1 243256034-243500092 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA025737, HPA044477, HPA072495 Approved Enhanced Centrosome Expressed in all Expressed in all thyroid gland: 24.2 Cell line enhanced WM-115: 31.8 +PTPRN IA-2 ENSG00000054356 Protein tyrosine phosphatase, receptor type N 2 219289623-219309648 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007152, HPA007179 Enhanced Approved Endoplasmic reticulum Glioma:2.45e-7 (unfavourable) Group enriched Tissue enriched 5 cerebral cortex: 183.1 adrenal gland: 35.0 Group enriched 8 U-2 OS: 70.1;U-87 MG: 244.6 +HHAT FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn ENSG00000054392 Hedgehog acyltransferase 1 210328252-210676296 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016462 Approved Approved Golgi apparatus Renal cancer:8.47e-7 (favourable) Expressed in all Mixed thyroid gland: 7.8 Cell line enhanced HMC-1: 11.9;RH-30: 12.0 +KIF1B CMT2, CMT2A, HMSNII, KIAA0591, KLP ENSG00000054523 Kinesin family member 1B 1 10210805-10381603 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015177 Approved Uncertain Nucleoli fibrillar center
Cytosol Renal cancer:2.91e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 105.4 Expressed in all +FOXC1 ARA, FKHL7, FREAC3, IGDA, IHG1, IRID1 ENSG00000054598 Forkhead box C1 6 1609972-1613897 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA040670 Enhanced Supported Nucleoplasm
Cytosol Colorectal cancer:3.53e-4 (unfavourable) Expressed in all Tissue enhanced salivary gland: 66.2 kidney: 21.8 Cell line enhanced AN3-CA: 86.7;HEK 293: 85.3 +TBC1D22A C22orf4 ENSG00000054611 TBC1 domain family member 22A 22 46762617-47175699 Predicted intracellular proteins Evidence at protein level HPA001173 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Liver cancer:2.42e-4 (unfavourable), Ovarian cancer:6.94e-4 (unfavourable) Expressed in all Expressed in all spleen: 22.1 Expressed in all +SYNE2 DKFZP434H2235, KIAA1011, Nesp2, Nesprin-2, NUA, NUANCE, SYNE-2 ENSG00000054654 Spectrin repeat containing nuclear envelope protein 2 14 63852983-64226433 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003435, HPA050204 Enhanced Enhanced Nuclear membrane Renal cancer:3.56e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 197.1 Cell line enhanced Daudi: 72.6 +PLEKHH1 KIAA1200 ENSG00000054690 Pleckstrin homology, MyTH4 and FERM domain containing H1 14 67533301-67589612 Predicted intracellular proteins Evidence at protein level HPA047707, HPA051964 Uncertain Approved Centrosome Renal cancer:4.03e-7 (favourable), Endometrial cancer:8.03e-5 (favourable), Urothelial cancer:2.26e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 43.3;thyroid gland: 51.2 prostate: 16.7 Cell line enhanced AN3-CA: 9.4;BEWO: 9.4;SK-MEL-30: 9.8;T-47d: 9.1 +ATP9A ATPIIA, KIAA0611 ENSG00000054793 ATPase phospholipid transporting 9A (putative) 20 51596514-51768634 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level CAB020699, HPA035630 Approved Renal cancer:5.67e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 155.8 Mixed +SPO11 CT35, SPATA43, TOPVIA ENSG00000054796 SPO11, initiator of meiotic double stranded breaks 20 57329759-57343994 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 154 testis: 15.3 all non-specific tissues: 0.0 Not detected +CBLN4 CBLNL1, dJ885A10.1 ENSG00000054803 Cerebellin 4 precursor 20 55997440-56005472 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA051496, HPA074497 Supported Approved Midbody ring Mixed Tissue enhanced adrenal gland: 24.5;cerebral cortex: 15.6;epididymis: 11.2 fallopian tube: 6.8 Cell line enriched 51 SH-SY5Y: 10.2 +CHRDL2 BNF1 ENSG00000054938 Chordin like 2 11 74696429-74731385 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021771 Uncertain Uncertain Mitochondria Urothelial cancer:6.08e-4 (unfavourable) Tissue enhanced Group enriched 9 appendix: 157.7;endometrium: 128.3;gallbladder: 168.5;smooth muscle: 183.1;urinary bladder: 43.5 cervix, uterine: 14.6 Cell line enhanced HeLa: 1.6;PC-3: 1.2;SiHa: 2.6 +FAM168A KIAA0280, TCRP1 ENSG00000054965 Family with sequence similarity 168 member A 11 73400487-73598189 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037580 Approved Approved Nucleoplasm Renal cancer:6.41e-5 (favourable), Endometrial cancer:5.51e-4 (unfavourable), Urothelial cancer:9.70e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 104.4 Expressed in all +RELT FLJ14993, TNFRSF19L ENSG00000054967 RELT tumor necrosis factor receptor 11 73376264-73397474 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA062824, HPA071518 Supported Nucleus Renal cancer:4.07e-11 (unfavourable) Mixed Tissue enriched 6 bone marrow: 95.8 spleen: 17.2 Mixed +GALC ENSG00000054983 Galactosylceramidase 14 87837820-87993665 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB022196 Approved Expressed in all Expressed in all testis: 44.0 Cell line enhanced CAPAN-2: 72.3;HMC-1: 67.2 +NOP58 HSPC120, NOP5 ENSG00000055044 NOP58 ribonucleoprotein 2 202265716-202303666 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018472, HPA021062 Supported Enhanced Nucleus
Nucleoli fibrillar center Renal cancer:3.38e-9 (unfavourable), Liver cancer:1.97e-6 (unfavourable), Ovarian cancer:9.86e-4 (favourable) Expressed in all Expressed in all lymph node: 69.3 Expressed in all +SZRD1 C1orf144, DKFZp566C0424 ENSG00000055070 SUZ RNA binding domain containing 1 1 16352575-16398145 Predicted intracellular proteins Evidence at protein level HPA024221 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:5.98e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 91.5 Expressed in all +KCNH2 erg1, HERG, Kv11.1, LQT2 ENSG00000055118 Potassium voltage-gated channel subfamily H member 2 7 150944961-150978315 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Endometrial cancer:6.06e-5 (unfavourable), Pancreatic cancer:5.61e-4 (favourable) Mixed Tissue enhanced bone marrow: 24.1;testis: 27.3 parathyroid gland: 13.2 Group enriched 6 K-562: 170.9;NB-4: 59.5;SH-SY5Y: 79.9 +CUL1 ENSG00000055130 Cullin 1 7 148697914-148801036 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002676, HPA064584 Supported Supported Nucleus
Nucleoli Expressed in all Expressed in all testis: 184.5 Expressed in all +FAM114A2 133K02, C5orf3 ENSG00000055147 Family with sequence similarity 114 member A2 5 153990128-154038936 Predicted intracellular proteins Evidence at protein level HPA035869, HPA035870 Approved Approved Vesicles Expressed in all Expressed in all testis: 68.7 Expressed in all +CYFIP2 PIR121 ENSG00000055163 Cytoplasmic FMR1 interacting protein 2 5 157266079-157395595 Predicted intracellular proteins Evidence at protein level CAB055519, HPA068106, HPA071459 Uncertain Approved Endoplasmic reticulum
Plasma membrane
Cytosol Renal cancer:3.21e-12 (favourable), Endometrial cancer:2.42e-6 (unfavourable), Pancreatic cancer:1.18e-4 (favourable) Expressed in all Expressed in all kidney: 166.2 Cell line enhanced Daudi: 156.3;MOLT-4: 169.6 +TAB2 KIAA0733, MAP3K7IP2 ENSG00000055208 TGF-beta activated kinase 1/MAP3K7 binding protein 2 6 149218641-149411613 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065436, HPA070137, HPA071215 Approved Supported Cytosol Expressed in all Expressed in all parathyroid gland: 70.3 Expressed in all +GINM1 C6orf72, dJ12G14.2 ENSG00000055211 Glycoprotein integral membrane 1 6 149566294-149591748 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017210, HPA041679 Approved Approved Nucleoli fibrillar center
Plasma membrane Expressed in all Expressed in all thyroid gland: 118.5 Expressed in all +EIF2AK2 EIF2AK1, PKR, PPP1R83, PRKR ENSG00000055332 Eukaryotic translation initiation factor 2 alpha kinase 2 2 37099210-37157065 Enzymes, Predicted intracellular proteins Evidence at protein level CAB003845, HPA019795, HPA063893 Approved Enhanced Cytosol Pancreatic cancer:2.08e-4 (unfavourable), Endometrial cancer:3.77e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.4 Mixed +USP36 FLJ12851, KIAA1453 ENSG00000055483 Ubiquitin specific peptidase 36 17 78787381-78841441 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012082, HPA012395, HPA052860 Uncertain Approved Enhanced Nucleoli
Nuclear speckles Endometrial cancer:5.18e-5 (unfavourable) Expressed in all Expressed in all skin: 38.4 Expressed in all +KMT2C HALR, KIAA1506, MLL3 ENSG00000055609 Lysine methyltransferase 2C 7 152134922-152436005 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA074736 Supported Nucleoplasm Renal cancer:8.01e-6 (favourable) Expressed in all Expressed in all skin: 25.0 Expressed in all +MCOLN3 FLJ11006, TRP-ML3, TRPML3 ENSG00000055732 Mucolipin 3 1 85018082-85048499 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA018106, HPA062137 Enhanced Approved Nucleoli
Cytosol Tissue enriched Tissue enhanced adrenal gland: 57.8;parathyroid gland: 42.8 epididymis: 17.5 Cell line enhanced HAP1: 13.4;RH-30: 15.2;SK-MEL-30: 22.2 +CCDC85A KIAA1912 ENSG00000055813 Coiled-coil domain containing 85A 2 56184123-56386173 Predicted secreted proteins Evidence at protein level HPA043106, HPA057020 Uncertain Mixed Tissue enhanced cerebral cortex: 21.0 thyroid gland: 15.9 Cell line enhanced Daudi: 34.0;fHDF/TERT166: 59.7;U-266/70: 25.2 +PUM2 KIAA0235, PUMH2 ENSG00000055917 Pumilio RNA binding family member 2 2 20248691-20352234 Predicted intracellular proteins Evidence at protein level HPA030316, HPA049670 Approved Enhanced Cytosol Liver cancer:5.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 98.1 Expressed in all +MRPL43 bMRP36a ENSG00000055950 Mitochondrial ribosomal protein L43 10 100969458-100987515 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA073022 Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all thyroid gland: 57.8 Expressed in all +ITIH4 H4P, IHRP, ITIHL1 ENSG00000055955 Inter-alpha-trypsin inhibitor heavy chain family member 4 3 52812975-52831479 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001835, HPA003948, CAB072872 Enhanced Approved Vesicles Tissue enriched Tissue enriched 71 liver: 984.5 skeletal muscle: 13.8 Cell line enhanced HDLM-2: 2.2;U-266/70: 2.1 +ITIH1 H1P, IATIH, ITIH ENSG00000055957 Inter-alpha-trypsin inhibitor heavy chain 1 3 52777592-52792068 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041639, HPA042049 Approved Approved Vesicles Liver cancer:1.89e-5 (favourable) Tissue enriched Tissue enriched 458 liver: 786.3 spleen: 1.7 Cell line enhanced ASC diff: 3.6;Hep G2: 1.1;HL-60: 1.0 +HPF1 C4orf27, FLJ20534 ENSG00000056050 Histone PARylation factor 1 4 169729465-169757953 Predicted intracellular proteins Evidence at protein level HPA043467 Uncertain Approved Approved Microtubules
Cytokinetic bridge
Cytosol Melanoma:5.63e-4 (unfavourable), Ovarian cancer:7.47e-4 (favourable) Expressed in all Expressed in all endometrium: 38.5 Expressed in all +ZFR SPG71, ZFR1 ENSG00000056097 Zinc finger RNA binding protein 5 32354350-32444761 Predicted intracellular proteins Evidence at protein level HPA016666 Supported Approved Nucleoplasm Liver cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 77.5 Expressed in all +ZNF280C FLJ20095, SUHW3, ZNF633 ENSG00000056277 Zinc finger protein 280C X 130202711-130268899 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051494, HPA055788 Enhanced Approved Nucleus
Nucleoli fibrillar center Expressed in all Tissue enhanced testis: 17.5 epididymis: 6.3 Mixed +NPFFR2 GPR74, NPFF2, NPGPR ENSG00000056291 Neuropeptide FF receptor 2 4 72031804-72148067 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026825 Approved Plasma membrane
Actin filaments Mixed Tissue enhanced placenta: 2.3;seminal vesicle: 4.6 epididymis: 1.1 Group enriched 11 NTERA-2: 9.2;RPTEC TERT1: 9.0;SH-SY5Y: 14.9;U-2 OS: 14.5 +PHF21B BHC80L, FLJ34161, PHF4 ENSG00000056487 PHD finger protein 21B 22 44881162-45009999 Predicted intracellular proteins Evidence at protein level HPA053834 Uncertain Uncertain Nucleus
Nucleoli fibrillar center Tissue enhanced Tissue enhanced cerebral cortex: 6.7;cervix, uterine: 5.5;testis: 6.4 endometrium: 5.4 Cell line enhanced AF22: 11.1;AN3-CA: 9.4;SCLC-21H: 10.3;SH-SY5Y: 41.0;U-2 OS: 9.1 +TRAF1 EBI6 ENSG00000056558 TNF receptor associated factor 1 9 120902393-120929173 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA001852, CAB009593 Enhanced Approved Nucleoplasm Pancreatic cancer:2.19e-5 (favourable), Renal cancer:4.42e-5 (unfavourable) Expressed in all Tissue enhanced lymph node: 37.6 appendix: 27.3 Group enriched 7 HDLM-2: 85.6;WM-115: 111.3 +RC3H2 FLJ20301, FLJ20713, MNAB, RNF164 ENSG00000056586 Ring finger and CCCH-type domains 2 9 122844556-122905341 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042863, HPA062144 Approved Supported Vesicles Renal cancer:5.50e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 25.5 Expressed in all +IL17RB CRL4, EVI27, IL17BR, IL17RH1 ENSG00000056736 Interleukin 17 receptor B 3 53846580-53865800 Predicted membrane proteins Evidence at protein level HPA005482 Supported Renal cancer:6.61e-4 (favourable) Expressed in all Tissue enhanced kidney: 61.7 cervix, uterine: 29.4 Cell line enhanced Hep G2: 40.4 +TRAF3IP2 ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZP586G0522 ENSG00000056972 TRAF3 interacting protein 2 6 111556454-111606278 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036352 Approved Approved Golgi apparatus
Vesicles Endometrial cancer:4.73e-5 (favourable), Renal cancer:5.16e-5 (unfavourable), Cervical cancer:3.21e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 50.8 Cell line enhanced U-2197: 94.7 +GYG2 GN-2 ENSG00000056998 Glycogenin 2 X 2828788-2882820 Enzymes, Predicted intracellular proteins Evidence at protein level HPA005495, HPA064686 Enhanced Approved Nucleus
Nucleoli
Cytosol Pancreatic cancer:3.01e-5 (favourable) Expressed in all Tissue enriched 13 adipose tissue: 173.1 breast: 13.2 Cell line enhanced AF22: 39.5;NTERA-2: 39.5;SK-MEL-30: 68.1 +DCBLD2 CLCP1, ESDN ENSG00000057019 Discoidin, CUB and LCCL domain containing 2 3 98795941-98901689 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016909 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Renal cancer:3.32e-5 (unfavourable), Pancreatic cancer:1.52e-4 (unfavourable), Stomach cancer:2.87e-4 (unfavourable) Expressed in all Mixed testis: 44.9 Cell line enhanced LHCN-M2: 647.4;U-87 MG: 568.7 +SERPINB3 HsT1196, SCC, SCCA1, T4-A ENSG00000057149 Serpin family B member 3 18 63655197-63661963 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018772, CAB036006, CAB036007, HPA048341, HPA049988, HPA055992 Enhanced Approved Plasma membrane
Cytosol Pancreatic cancer:3.19e-4 (unfavourable) Tissue enhanced Group enriched 7 cervix, uterine: 298.5;esophagus: 848.0 urinary bladder: 87.5 Cell line enhanced HaCaT: 5.5;SiHa: 4.1;U-2197: 7.3 +SOAT1 ACAT, SOAT, STAT ENSG00000057252 Sterol O-acyltransferase 1 1 179293714-179358680 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB009533, HPA047171 Enhanced Enhanced Endoplasmic reticulum Expressed in all Tissue enhanced adrenal gland: 218.2 prostate: 45.1 Expressed in all +PKP2 ENSG00000057294 Plakophilin 2 12 32790745-32896840 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA014314, CAB037336, HPA056908 Enhanced Enhanced Nucleoplasm
Cell Junctions Lung cancer:6.79e-4 (unfavourable), Colorectal cancer:8.55e-4 (favourable) Mixed Tissue enhanced fallopian tube: 114.2;heart muscle: 123.3 parathyroid gland: 50.6 Cell line enhanced CACO-2: 161.1 +MSH4 ENSG00000057468 MutS homolog 4 1 75796882-75913238 Predicted intracellular proteins Evidence at protein level Not detected Group enriched 7 epididymis: 2.3;testis: 7.7 spleen: 0.7 Cell line enhanced AN3-CA: 1.6 +F7 ENSG00000057593 Coagulation factor VII 13 113105788-113120681 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA004826 Approved Mitochondria Tissue enriched Tissue enriched 44 liver: 65.0 testis: 1.4 Group enriched 7 CACO-2: 11.8;Hep G2: 6.1 +GDI2 RABGDIB ENSG00000057608 GDP dissociation inhibitor 2 10 5765223-5842132 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049290, HPA057668 Supported Liver cancer:7.56e-7 (unfavourable), Glioma:7.00e-4 (favourable) Expressed in all Expressed in all lymph node: 241.2 Expressed in all +PRDM1 BLIMP1, PRDI-BF1 ENSG00000057657 PR/SET domain 1 6 106086320-106109939 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030033 Approved Approved Nucleus
Nucleoli Renal cancer:9.81e-5 (unfavourable) Expressed in all Tissue enhanced esophagus: 61.0 endometrium: 30.1 Cell line enhanced Karpas-707: 158.5;U-266/70: 62.6;U-266/84: 39.9 +ATG5 APG5, APG5L, ASP, hAPG5 ENSG00000057663 Autophagy related 5 6 106045423-106325791 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB034432, CAB037309, HPA042973 Enhanced Approved Centrosome Renal cancer:8.73e-4 (unfavourable), Liver cancer:8.84e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 32.3 Expressed in all +TMCC3 KIAA1145 ENSG00000057704 Transmembrane and coiled-coil domain family 3 12 94567124-94650562 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014272 Approved Approved Endoplasmic reticulum
Vesicles Endometrial cancer:4.87e-4 (unfavourable) Expressed in all Mixed placenta: 25.7 Cell line enhanced HUVEC TERT2: 26.1;Karpas-707: 30.1;U-266/84: 20.9 +PITHD1 C1orf128, HT014, TXNL1CL ENSG00000057757 PITH domain containing 1 1 23778405-23788232 Predicted intracellular proteins Evidence at protein level HPA016936 Uncertain Expressed in all Expressed in all parathyroid gland: 208.8 Expressed in all +MTA3 KIAA1266 ENSG00000057935 Metastasis associated 1 family member 3 2 42494569-42756947 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA039433 Approved Supported Nucleus
Vesicles Endometrial cancer:2.30e-4 (unfavourable), Liver cancer:4.69e-4 (unfavourable) Expressed in all Expressed in all testis: 52.4 Mixed +USP13 IsoT-3 ENSG00000058056 Ubiquitin specific peptidase 13 (isopeptidase T-3) 3 179652755-179789401 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004827 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.46e-6 (unfavourable), Liver cancer:2.40e-5 (unfavourable), Urothelial cancer:3.06e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 52.2 Mixed +ATP11B ATPIF, ATPIR, KIAA0956 ENSG00000058063 ATPase phospholipid transporting 11B (putative) 3 182793500-182921635 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level HPA036237, HPA036238 Uncertain Approved Microtubule organizing center
Cytosol Pancreatic cancer:1.09e-4 (unfavourable), Endometrial cancer:3.44e-4 (unfavourable) Expressed in all Expressed in all testis: 58.0 Expressed in all +LAMC2 BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa ENSG00000058085 Laminin subunit gamma 2 1 183186238-183244900 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB004257, HPA024638, CAB078165 Enhanced Approved Cytosol Lung cancer:4.20e-6 (unfavourable), Pancreatic cancer:7.11e-5 (unfavourable) Tissue enhanced Tissue enhanced fallopian tube: 57.8 lung: 38.9 Cell line enhanced A-431: 521.5;CAPAN-2: 460.7;HBEC3-KT: 1872.4;hTERT-HME1: 1202.0;RPTEC TERT1: 464.3 +CDK14 PFTAIRE1, PFTK1 ENSG00000058091 Cyclin dependent kinase 14 7 90466424-91210590 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015267 Approved Supported Nucleus
Cytosol Breast cancer:5.86e-4 (favourable), Stomach cancer:7.79e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 56.7 Mixed +SEC61A1 ENSG00000058262 Sec61 translocon alpha 1 subunit 3 128051641-128071683 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB022076 Supported Endoplasmic reticulum Renal cancer:6.84e-9 (unfavourable), Liver cancer:1.07e-6 (unfavourable), Endometrial cancer:7.82e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 218.2 Expressed in all +PPP1R12A M130, MBS, MYPT1 ENSG00000058272 Protein phosphatase 1 regulatory subunit 12A 12 79773563-79935460 Predicted intracellular proteins Evidence at protein level HPA041296, HPA071956 Approved Enhanced Actin filaments
Cytosol Liver cancer:1.72e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 120.9 Expressed in all +RASGRF1 CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187 ENSG00000058335 Ras protein specific guanine nucleotide releasing factor 1 15 78959947-79090773 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010413, HPA041965 Approved Supported Golgi apparatus Endometrial cancer:6.14e-6 (favourable) Mixed Group enriched 14 cerebral cortex: 30.5;lung: 11.3 lymph node: 1.5 Cell line enhanced A-431: 7.3;BEWO: 7.5;Karpas-707: 7.5;RPMI-8226: 9.0;U-2 OS: 15.8 +CAMK2B CAM2, CAMK2, CAMKB ENSG00000058404 Calcium/calmodulin dependent protein kinase II beta 7 44217150-44334577 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB006849, HPA026307, HPA051783, HPA051785, HPA053973 Enhanced Supported Supported Plasma membrane
Cell Junctions
Cytosol Mixed Tissue enhanced cerebral cortex: 214.1 skeletal muscle: 46.1 Cell line enriched 12 SCLC-21H: 88.9 +CROCC ROLT, rootletin ENSG00000058453 Ciliary rootlet coiled-coil, rootletin 1 16740273-16972979 Predicted intracellular proteins Evidence at protein level HPA021191, HPA021762 Enhanced Supported Plasma membrane
Centrosome Endometrial cancer:8.34e-5 (favourable), Lung cancer:7.92e-4 (favourable), Renal cancer:7.97e-4 (unfavourable) Expressed in all Mixed skin: 11.6 Mixed +POLR3E FLJ10509, RPC5, SIN ENSG00000058600 RNA polymerase III subunit E 16 22297375-22335103 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA041419, HPA041477 Approved Enhanced Nucleoplasm Prostate cancer:1.74e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 8.9 Expressed in all +ATP2B4 ATP2B2, MXRA1, PMCA4 ENSG00000058668 ATPase plasma membrane Ca2+ transporting 4 1 203626561-203744081 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB016118, HPA040431 Enhanced Supported Plasma membrane Renal cancer:1.21e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 254.6 Expressed in all +ZC3H11A KIAA0663, ZC3HDC11A ENSG00000058673 Zinc finger CCCH-type containing 11A 1 203795654-203854999 Predicted intracellular proteins Evidence at protein level HPA026439, HPA028490, HPA028526 Approved Approved Nuclear speckles Renal cancer:5.58e-4 (unfavourable) Expressed in all Expressed in all testis: 41.6 Expressed in all +RIOK2 FLJ11159 ENSG00000058729 RIO kinase 2 5 97160867-97183260 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005681 Uncertain Approved Plasma membrane
Cytosol Expressed in all Expressed in all testis: 22.1 Expressed in all +YIPF1 DJ167A19.1, FinGER1 ENSG00000058799 Yip1 domain family member 1 1 53851719-53889834 Predicted membrane proteins Evidence at protein level HPA014716 Approved Approved Nucleoplasm Liver cancer:1.34e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 35.0 Expressed in all +NDC1 FLJ10407, NET3, TMEM48 ENSG00000058804 NDC1 transmembrane nucleoporin 1 53765460-53838860 Predicted membrane proteins, Transporters Evidence at protein level HPA069751, HPA070882 Approved Supported Nuclear membrane
Plasma membrane
Actin filaments Liver cancer:7.52e-7 (unfavourable), Colorectal cancer:4.48e-5 (favourable), Pancreatic cancer:3.58e-4 (unfavourable) Expressed in all Mixed lymph node: 16.4 Expressed in all +DGKG DAGK3 ENSG00000058866 Diacylglycerol kinase gamma 3 186105668-186362237 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036577 Approved Approved Vesicles
Plasma membrane Tissue enhanced Tissue enhanced cerebral cortex: 21.4 placenta: 11.3 Cell line enhanced HDLM-2: 22.1;U-87 MG: 13.9 +FLYWCH1 DKFZp761A132 ENSG00000059122 FLYWCH-type zinc finger 1 16 2911937-2951208 Predicted intracellular proteins Evidence at protein level HPA040753, HPA041001 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all parathyroid gland: 30.3 Expressed in all +UNKL C16orf28, FLJ23360, ZC3H5L, ZC3HDC5L ENSG00000059145 Unkempt family like zinc finger 16 1363205-1414751 Predicted intracellular proteins Evidence at protein level HPA055801, HPA073949 Approved Supported Cytosol Expressed in all Mixed endometrium: 9.6 Mixed +TBXAS1 CYP5, CYP5A1, THAS, TS, TXAS, TXS ENSG00000059377 Thromboxane A synthase 1 7 139777051-140020325 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031257, HPA031258, HPA031259 Enhanced Supported Vesicles Renal cancer:1.14e-4 (unfavourable) Expressed in all Mixed spleen: 56.3 Cell line enhanced NB-4: 48.5;PC-3: 22.1;U-937: 48.2 +PARP12 FLJ22693, PARP-12, ZC3H1, ZC3HDC1 ENSG00000059378 Poly(ADP-ribose) polymerase family member 12 7 140023744-140063721 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003584, HPA063872 Approved Approved Nucleus Renal cancer:4.12e-7 (unfavourable), Liver cancer:1.63e-4 (unfavourable) Expressed in all Mixed skin: 13.8 Mixed +ALDH18A1 GSAS, P5CS, PYCS, SPG9 ENSG00000059573 Aldehyde dehydrogenase 18 family member A1 10 95605929-95656706 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA008333, HPA012604 Approved Enhanced Mitochondria Renal cancer:3.60e-9 (unfavourable), Endometrial cancer:4.20e-4 (favourable) Expressed in all Expressed in all duodenum: 89.5 Expressed in all +TARBP1 TRM3, TRP-185 ENSG00000059588 TAR (HIV-1) RNA binding protein 1 1 234391313-234479103 Predicted intracellular proteins Evidence at protein level CAB020810, HPA024632 Uncertain Approved Nuclear speckles Renal cancer:5.14e-10 (unfavourable) Expressed in all Expressed in all parathyroid gland: 16.1 Expressed in all +GATB PET112, PET112L ENSG00000059691 Glutamyl-tRNA amidotransferase subunit B 4 151670504-151761023 Predicted intracellular proteins Evidence at protein level HPA042610 Uncertain Supported Mitochondria Renal cancer:1.20e-10 (favourable) Expressed in all Mixed kidney: 22.4 Expressed in all +MXD1 bHLHc58, MAD, MAD1 ENSG00000059728 MAX dimerization protein 1 2 69897688-69942945 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001599 Enhanced Uncertain Nucleoplasm
Mitochondria
Cytosol Endometrial cancer:8.14e-6 (unfavourable), Pancreatic cancer:8.50e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 113.8;esophagus: 101.9 appendix: 56.3 Mixed +CDK17 PCTAIRE2, PCTK2 ENSG00000059758 Cyclin dependent kinase 17 12 96278261-96400560 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015325 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.09e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 71.8 Expressed in all +DNAJC25 bA16L21.2.1 ENSG00000059769 DnaJ heat shock protein family (Hsp40) member C25 9 111631352-111654351 Predicted membrane proteins Evidence at protein level HPA019122 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:3.73e-4 (favourable) Expressed in all Tissue enhanced liver: 16.7 parathyroid gland: 7.9 Mixed +SLC2A3 GLUT3 ENSG00000059804 Solute carrier family 2 member 3 12 7919230-7936275 Predicted membrane proteins, Transporters Evidence at protein level CAB002763, HPA006539 Approved Approved Plasma membrane Renal cancer:6.36e-8 (unfavourable), Stomach cancer:2.89e-5 (unfavourable), Colorectal cancer:8.58e-4 (unfavourable) Tissue enriched Tissue enhanced bone marrow: 271.2 placenta: 138.7 Group enriched 7 BEWO: 1387.7;CACO-2: 1315.8;NTERA-2: 293.2 +PSD EFA6, EFA6A, KIAA2011, PSD1, TYL ENSG00000059915 Pleckstrin and Sec7 domain containing 10 102402617-102421539 Predicted intracellular proteins Evidence at protein level HPA059237 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Mixed Tissue enhanced cerebral cortex: 112.7 endometrium: 40.4 Cell line enhanced HSkMC: 5.6;SCLC-21H: 8.7;SH-SY5Y: 6.8 +CTDP1 FCP1 ENSG00000060069 CTD phosphatase subunit 1 18 79679801-79756623 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB032641, HPA040394, HPA070389 Supported Approved Nucleoplasm
Vesicles Renal cancer:5.51e-5 (favourable), Endometrial cancer:6.43e-4 (favourable) Expressed in all Expressed in all testis: 19.6 Expressed in all +YBX3 CSDA, CSDA1, dbpA, ZONAB ENSG00000060138 Y-box binding protein 3 12 10699089-10723312 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034838 Approved Supported Cytosol Renal cancer:6.17e-13 (unfavourable) Expressed in all Expressed in all skeletal muscle: 1300.9 Mixed +STYK1 DKFZp761P1010, NOK, SuRTK106 ENSG00000060140 Serine/threonine/tyrosine kinase 1 12 10618939-10674318 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040468, HPA048569 Uncertain Approved Nucleus
Plasma membrane Mixed Mixed rectum: 17.4 Cell line enhanced CAPAN-2: 23.5;HUVEC TERT2: 20.0;TIME: 18.2 +WNK1 HSAN2, HSN2, PPP1R167, PRKWNK1 ENSG00000060237 WNK lysine deficient protein kinase 1 12 752593-911452 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046541, HPA059157 Enhanced Supported Cytosol Ovarian cancer:9.67e-4 (unfavourable) Expressed in all Expressed in all esophagus: 92.4 Expressed in all +CCAR1 CARP-1, CARP1, FLJ10590 ENSG00000060339 Cell division cycle and apoptosis regulator 1 10 68721012-68792377 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA007856, HPA048513 Supported Supported Nucleoplasm
Golgi apparatus Liver cancer:1.41e-5 (unfavourable), Ovarian cancer:4.05e-5 (favourable), Renal cancer:1.37e-4 (unfavourable) Expressed in all Expressed in all lymph node: 34.8 Expressed in all +OGFR 7-60 ENSG00000060491 Opioid growth factor receptor 20 62804835-62814000 Predicted intracellular proteins Evidence at protein level HPA017899 Enhanced Approved Nucleoplasm Urothelial cancer:5.19e-4 (favourable) Expressed in all Expressed in all spleen: 52.6 Expressed in all +GNA15 GNA16 ENSG00000060558 G protein subunit alpha 15 19 3136193-3163769 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043113 Approved Renal cancer:4.26e-6 (unfavourable), Breast cancer:7.57e-5 (favourable), Endometrial cancer:2.01e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 48.7;esophagus: 61.3 skin: 25.9 Cell line enhanced HMC-1: 142.1;MOLT-4: 137.5;REH: 115.4 +CREB3L3 CREB-H ENSG00000060566 CAMP responsive element binding protein 3 like 3 19 4153601-4173054 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA040671, HPA056228 Enhanced Renal cancer:3.53e-6 (unfavourable) Tissue enriched Group enriched 104 duodenum: 241.6;liver: 61.0;small intestine: 278.7 colon,stomach: 1.8 Cell line enhanced HDLM-2: 44.9;Hep G2: 10.3;U-266/70: 7.7 +PIGV FLJ20477 ENSG00000060642 Phosphatidylinositol glycan anchor biosynthesis class V 1 26787472-26798398 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054181 Approved Endoplasmic reticulum
Cytosol Renal cancer:7.60e-7 (favourable) Expressed in all Expressed in all testis: 79.6 Expressed in all +PTPRU FMI, hPTP-J, PCP-2, PTP, PTPRO ENSG00000060656 Protein tyrosine phosphatase, receptor type U 1 29236516-29326813 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011476, HPA039832 Approved Head and neck cancer:8.32e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 28.0 Cell line enhanced BEWO: 92.2 +SNRNP40 HPRP8BP, PRP8BP, PRPF8BP, SPF38, WDR57 ENSG00000060688 Small nuclear ribonucleoprotein U5 subunit 40 1 31259568-31296782 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026527, HPA027345 Supported Supported Nuclear speckles Liver cancer:4.73e-6 (unfavourable), Glioma:9.74e-4 (favourable) Expressed in all Expressed in all lymph node: 40.9 Expressed in all +RIMBP2 KIAA0318, MGC15831, PPP1R133, RBP2, RIM-BP2 ENSG00000060709 RIMS binding protein 2 12 130396137-130517917 Predicted intracellular proteins Evidence at protein level Pancreatic cancer:4.16e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 95.0 cerebral cortex: 24.4 Group enriched 10 SCLC-21H: 26.1;SH-SY5Y: 41.8 +COL11A1 CO11A1, COLL6, STL2 ENSG00000060718 Collagen type XI alpha 1 chain 1 102876467-103108496 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA058335 Approved Endoplasmic reticulum Mixed Tissue enriched 6 placenta: 27.9 gallbladder: 4.7 Cell line enhanced AF22: 113.0;BJ hTERT+ SV40 Large T+ RasG12V: 78.6;HBF TERT88: 46.0;HSkMC: 101.5 +QSER1 FLJ21924 ENSG00000060749 Glutamine and serine rich 1 11 32893178-32993316 Predicted intracellular proteins Evidence at protein level HPA005682 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:5.27e-5 (unfavourable), Liver cancer:7.94e-5 (unfavourable), Renal cancer:6.87e-4 (unfavourable) Expressed in all Expressed in all testis: 17.4 Expressed in all +MPC1 BRP44L, CGI-129, dJ68L15.3 ENSG00000060762 Mitochondrial pyruvate carrier 1 6 166364919-166383013 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA045119, HPA055790 Enhanced Enhanced Mitochondria Renal cancer:4.79e-11 (favourable), Lung cancer:1.29e-4 (favourable), Cervical cancer:1.45e-4 (favourable) Expressed in all Expressed in all heart muscle: 432.9 Expressed in all +ACAA1 ENSG00000060971 Acetyl-CoA acyltransferase 1 3 38103129-38137242 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006764, HPA007244 Enhanced Enhanced Peroxisomes Renal cancer:6.99e-9 (favourable), Head and neck cancer:1.23e-4 (favourable), Breast cancer:3.00e-4 (favourable), Endometrial cancer:7.53e-4 (favourable) Expressed in all Expressed in all liver: 328.4 Expressed in all +BCAT1 BCT1 ENSG00000060982 Branched chain amino acid transaminase 1 12 24810022-24949459 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048592 Uncertain Renal cancer:1.38e-4 (unfavourable), Head and neck cancer:3.55e-4 (unfavourable), Stomach cancer:4.95e-4 (unfavourable), Urothelial cancer:8.54e-4 (unfavourable) Expressed in all Mixed placenta: 21.4 Cell line enhanced NTERA-2: 283.1;RH-30: 298.1 +HDAC7 DKFZP586J0917, HDAC7A ENSG00000061273 Histone deacetylase 7 12 47782722-47833132 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004775 Supported Cytosol Urothelial cancer:4.65e-4 (favourable), Melanoma:5.16e-4 (unfavourable), Renal cancer:8.25e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 43.9 Expressed in all +LZTS1 FEZ1 ENSG00000061337 Leucine zipper tumor suppressor 1 8 20246165-20303963 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006294, HPA022046 Approved Approved Nucleoli
Plasma membrane Renal cancer:9.28e-6 (unfavourable), Endometrial cancer:3.03e-4 (unfavourable) Expressed in all Tissue enriched 10 parathyroid gland: 125.4 testis: 12.4 Cell line enhanced SK-MEL-30: 59.3;WM-115: 50.1 +PRDM6 KMT8C, PRISM ENSG00000061455 PR/SET domain 6 5 123089121-123194266 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030322, HPA030324 Uncertain Uncertain Nucleoplasm Mixed Tissue enhanced gallbladder: 5.2;placenta: 5.9 lung: 4.0 Cell line enhanced BEWO: 3.5;HEK 293: 4.7 +WNT8A WNT8D ENSG00000061492 Wnt family member 8A 5 138083892-138092365 Predicted secreted proteins Evidence at transcript level HPA038539 Uncertain Uncertain Plasma membrane
Cytosol Tissue enriched Not detected testis: 0.7 Not detected +SPAG4 CT127, SUN4 ENSG00000061656 Sperm associated antigen 4 20 35615892-35621049 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048393, HPA061789 Approved Endometrial cancer:9.52e-8 (favourable), Colorectal cancer:1.09e-5 (unfavourable), Glioma:8.89e-5 (unfavourable), Renal cancer:1.28e-4 (unfavourable), Urothelial cancer:6.66e-4 (favourable) Expressed in all Mixed testis: 22.5 Cell line enhanced EFO-21: 25.0;U-87 MG: 46.8 +NCKAP1 HEM2, Nap1, NAP125 ENSG00000061676 NCK associated protein 1 2 182909115-183038858 Predicted membrane proteins Evidence at protein level HPA020449 Enhanced Approved Cytosol Pancreatic cancer:3.81e-4 (unfavourable), Lung cancer:9.71e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 145.1 Mixed +MRPS35 MDS023, MRPS28 ENSG00000061794 Mitochondrial ribosomal protein S35 12 27710773-27756295 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA038513 Enhanced Approved Mitochondria
Cytosol Renal cancer:1.51e-5 (favourable), Liver cancer:1.64e-4 (unfavourable), Colorectal cancer:5.01e-4 (favourable), Breast cancer:9.41e-4 (unfavourable) Expressed in all Expressed in all kidney: 78.7 Expressed in all +GUCY1B3 GC-S-beta-1, GC-SB3, GUC1B3 ENSG00000061918 Guanylate cyclase 1 soluble subunit beta 4 155758992-155807591 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010890, HPA020870 Approved Approved Cytosol Renal cancer:2.42e-4 (unfavourable), Testis cancer:3.23e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 177.3 Cell line enhanced HEL: 42.7;MOLT-4: 24.5;RPTEC TERT1: 35.1 +SFSWAP SFRS8, SWAP ENSG00000061936 Splicing factor SWAP homolog 12 131711081-131799737 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039362, HPA040063 Approved Approved Nucleus
Plasma membrane
Cytosol Renal cancer:3.33e-8 (unfavourable), Melanoma:1.10e-4 (unfavourable) Expressed in all Expressed in all skin: 18.1 Expressed in all +TNK2 ACK, ACK1, p21cdc42Hs ENSG00000061938 Tyrosine kinase non receptor 2 3 195863364-195911945 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041954 Approved Approved Cytosol Urothelial cancer:1.00e-4 (favourable), Renal cancer:1.30e-4 (unfavourable), Endometrial cancer:8.96e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 109.5 Expressed in all +MON2 KIAA1040 ENSG00000061987 MON2 homolog, regulator of endosome-to-Golgi trafficking 12 62466817-62600479 Predicted intracellular proteins Evidence at protein level HPA038697, HPA057607 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center Head and neck cancer:2.03e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 34.8 Expressed in all +CDH3 CDHP, PCAD ENSG00000062038 Cadherin 3 16 68636189-68722616 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001767, CAB002487 Enhanced Uncertain Cell Junctions
Cytosol Pancreatic cancer:8.43e-4 (unfavourable), Lung cancer:8.53e-4 (unfavourable) Mixed Tissue enhanced skin: 31.9 ovary: 26.5 Cell line enhanced A-431: 89.4;HaCaT: 243.8;HBEC3-KT: 95.6;hTCEpi: 75.4;RPTEC TERT1: 88.7 +ARSF ENSG00000062096 Arylsulfatase F X 3041471-3112726 Predicted membrane proteins Evidence at protein level HPA000549 Uncertain Cytosol Tissue enhanced Group enriched 6 adrenal gland: 4.0;cerebral cortex: 2.1;epididymis: 2.0;esophagus: 2.3;kidney: 8.0;skin: 6.7 liver: 0.6 Not detected +GPBP1 DKFZp761C169, vasculin ENSG00000062194 GC-rich promoter binding protein 1 5 57173948-57264679 Predicted intracellular proteins Evidence at protein level HPA037773 Approved Approved Vesicles
Plasma membrane
Cytosol Urothelial cancer:4.15e-5 (favourable) Expressed in all Expressed in all testis: 138.7 Expressed in all +DGAT2 ENSG00000062282 Diacylglycerol O-acyltransferase 2 11 75759512-75801535 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Endometrial cancer:2.84e-4 (unfavourable) Tissue enhanced Tissue enhanced adipose tissue: 493.2;liver: 170.9 skin: 116.1 Cell line enhanced ASC diff: 55.2;HDLM-2: 57.8 +ZNF112 ZFP112, ZNF228 ENSG00000062370 Zinc finger protein 112 19 44326555-44367217 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA023856 Approved Approved Centrosome Renal cancer:1.54e-5 (favourable) Mixed Mixed testis: 13.8 Cell line enhanced U-2197: 16.1 +CS ENSG00000062485 Citrate synthase 12 56271699-56300392 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754 Enhanced Enhanced Mitochondria Renal cancer:1.17e-4 (favourable) Expressed in all Expressed in all heart muscle: 190.9 Expressed in all +LTK TYK1 ENSG00000062524 Leukocyte receptor tyrosine kinase 15 41503638-41513887 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA059545 Uncertain Approved Vesicles Mixed Mixed placenta: 15.2 Cell line enhanced HEL: 4.4;NB-4: 6.1;RH-30: 4.4;THP-1: 9.9 +MRPS24 HSPC335, MRP-S24 ENSG00000062582 Mitochondrial ribosomal protein S24 7 43866558-43869893 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA020983 Approved Nucleoplasm
Vesicles Lung cancer:1.91e-4 (unfavourable), Renal cancer:9.89e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 147.5 Expressed in all +ELMO2 CED-12, CED12, ELMO-2, FLJ11656, KIAA1834 ENSG00000062598 Engulfment and cell motility 2 20 46366049-46432985 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018811 Approved Supported Cytosol Liver cancer:4.08e-5 (unfavourable), Pancreatic cancer:6.10e-4 (favourable), Endometrial cancer:6.54e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 58.2 Expressed in all +WAPL FOE, KIAA0261, WAPAL ENSG00000062650 WAPL cohesin release factor 10 86435256-86521815 Predicted intracellular proteins Evidence at protein level HPA037874, HPA037875 Enhanced Expressed in all Expressed in all testis: 64.5 Expressed in all +VMP1 EPG3, TANGO5, TMEM49 ENSG00000062716 Vacuole membrane protein 1 17 59707192-59842255 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030773, HPA064780 Uncertain Approved Nucleoli
Endoplasmic reticulum Renal cancer:2.77e-8 (unfavourable), Endometrial cancer:1.56e-5 (unfavourable), Liver cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all spleen: 63.4 Expressed in all +APPBP2 Hs.84084, KIAA0228, PAT1 ENSG00000062725 Amyloid beta precursor protein binding protein 2 17 60443149-60526219 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Liver cancer:3.65e-4 (unfavourable) Expressed in all Expressed in all testis: 44.6 Expressed in all +POLD1 CDC2, POLD ENSG00000062822 DNA polymerase delta 1, catalytic subunit 19 50384204-50418018 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004375, HPA046524 Enhanced Supported Nucleoplasm Liver cancer:2.87e-6 (unfavourable) Expressed in all Mixed bone marrow: 21.4 Expressed in all +SEZ6 ENSG00000063015 Seizure related 6 homolog 17 28954901-29006440 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011777 Enhanced Uncertain Intermediate filaments Tissue enriched Tissue enriched 53 cerebral cortex: 54.3 duodenum: 1.0 Cell line enriched 6 SCLC-21H: 69.9 +EIF4B ENSG00000063046 Eukaryotic translation initiation factor 4B 12 53006158-53042209 Predicted intracellular proteins Evidence at protein level HPA039072, HPA046164 Approved Enhanced Cytosol Expressed in all Expressed in all ovary: 757.9 Expressed in all +SLC6A16 NTT5 ENSG00000063127 Solute carrier family 6 member 16 19 49289638-49325225 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA076812 Supported Golgi apparatus Mixed Tissue enriched 18 testis: 162.8 lymph node: 8.8 Cell line enhanced AF22: 18.0 +GLTSCR1 ENSG00000063169 Glioma tumor suppressor candidate region gene 1 19 47608196-47703277 Predicted intracellular proteins Evidence at protein level HPA056211 Approved Approved Nucleoplasm Head and neck cancer:1.34e-4 (favourable), Renal cancer:1.82e-4 (unfavourable), Urothelial cancer:9.34e-4 (favourable) Expressed in all Mixed parathyroid gland: 15.4 Expressed in all +SPHK2 ENSG00000063176 Sphingosine kinase 2 19 48619291-48630717 Enzymes, Predicted intracellular proteins Evidence at protein level HPA065508 Supported Vesicles Renal cancer:2.59e-5 (favourable), Endometrial cancer:5.19e-4 (unfavourable), Pancreatic cancer:9.30e-4 (favourable) Expressed in all Mixed duodenum: 22.1 Expressed in all +RPL18 L18 ENSG00000063177 Ribosomal protein L18 19 48615328-48619536 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046572 Approved Enhanced Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:1.21e-4 (unfavourable) Expressed in all Expressed in all ovary: 2572.0 Expressed in all +CA11 CARP2, CARPX1 ENSG00000063180 Carbonic anhydrase 11 19 48637942-48646312 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041778 Approved Vesicles
Microtubules Lung cancer:2.11e-5 (favourable), Pancreatic cancer:8.60e-5 (favourable), Cervical cancer:4.33e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 244.1 ovary: 49.5 Cell line enhanced AN3-CA: 39.9;SCLC-21H: 35.8 +ISOC2 FLJ23469 ENSG00000063241 Isochorismatase domain containing 2 19 55452985-55462343 Predicted intracellular proteins Evidence at protein level HPA043142 Enhanced Approved Mitochondria
Cytosol Expressed in all Expressed in all kidney: 63.1 Mixed +U2AF2 U2AF65 ENSG00000063244 U2 small nuclear RNA auxiliary factor 2 19 55654146-55674715 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010910, HPA041943, HPA043562 Supported Supported Enhanced Nucleoplasm
Nuclear speckles Liver cancer:1.54e-6 (unfavourable) Expressed in all Expressed in all lymph node: 137.2 Expressed in all +EPN1 ENSG00000063245 Epsin 1 19 55675226-55709858 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009729, HPA061136 Approved Enhanced Cytosol Expressed in all Expressed in all duodenum: 89.4 Expressed in all +MED29 DKFZp434H247, IXL, MED2 ENSG00000063322 Mediator complex subunit 29 19 39391303-39400637 Predicted intracellular proteins Evidence at protein level HPA055956 Supported Nucleoplasm Renal cancer:5.15e-5 (favourable), Endometrial cancer:7.27e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 64.5 Expressed in all +AHRR AHH, AHHR, bHLHe77, KIAA1234 ENSG00000063438 Aryl-hydrocarbon receptor repressor 5 304176-438291 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021483 Supported Nucleoplasm
Cytosol Mixed Tissue enriched 8 testis: 65.2 skin: 7.9 Cell line enhanced HMC-1: 89.0;NB-4: 80.8;WM-115: 71.5 +GSC2 GSCL ENSG00000063515 Goosecoid homeobox 2 22 19148576-19150283 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA043011 Uncertain Not detected Tissue enriched 31 testis: 3.0 all non-specific tissues: 0.0 Not detected +ZNF275 ENSG00000063587 Zinc finger protein 275 X 153334155-153360110 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000566 Approved Approved Nucleoli Expressed in all Expressed in all adrenal gland: 79.3 Cell line enhanced U-266/70: 46.8 +MTMR1 ENSG00000063601 Myotubularin related protein 1 X 150692971-150765103 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002977, HPA018502 Approved Approved Microtubule organizing center Expressed in all Expressed in all parathyroid gland: 26.6 Mixed +GPC1 glypican ENSG00000063660 Glypican 1 2 240435671-240468078 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030571 Approved Supported Plasma membrane
Cytosol Liver cancer:2.44e-6 (unfavourable), Colorectal cancer:5.78e-5 (unfavourable), Endometrial cancer:1.55e-4 (unfavourable) Expressed in all Tissue enhanced skin: 265.8 prostate: 67.5 Mixed +ADCK1 FLJ39600 ENSG00000063761 AarF domain containing kinase 1 14 77800083-77935012 Enzymes, Predicted secreted proteins Evidence at protein level HPA051012, HPA055014 Uncertain Approved Nucleoplasm Renal cancer:5.82e-6 (favourable), Lung cancer:4.11e-5 (favourable), Liver cancer:1.70e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 9.0 Mixed +HAGH GLO2, GLXII, HAGH1 ENSG00000063854 Hydroxyacylglutathione hydrolase 16 1795620-1827194 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043041, HPA061143 Approved Renal cancer:1.81e-6 (favourable), Liver cancer:5.33e-6 (favourable), Cervical cancer:5.82e-5 (favourable), Urothelial cancer:5.19e-4 (favourable) Expressed in all Expressed in all liver: 124.4 Expressed in all +RNF4 RES4-26, SLX5, SNURF ENSG00000063978 Ring finger protein 4 4 2462220-2625320 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049356 Approved Lung cancer:6.38e-4 (unfavourable) Expressed in all Expressed in all testis: 57.0 Expressed in all +CASP8 Casp-8, FLICE, MACH, MCH5 ENSG00000064012 Caspase 8 2 201233443-201287711 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001302, CAB002047, HPA005688, HPA006191 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.27e-6 (unfavourable), Ovarian cancer:1.25e-4 (favourable), Liver cancer:3.02e-4 (unfavourable) Expressed in all Expressed in all spleen: 44.8 Expressed in all +LIMCH1 DKFZP686A01247, LIMCH1A, LMO7B ENSG00000064042 LIM and calponin homology domains 1 4 41359607-41700044 Predicted intracellular proteins Evidence at protein level HPA004184, HPA063840 Uncertain Approved Actin filaments Renal cancer:3.82e-7 (favourable), Breast cancer:5.55e-6 (unfavourable) Expressed in all Mixed parathyroid gland: 190.9 Cell line enhanced HeLa: 126.0;RT4: 144.1;SiHa: 108.5;WM-115: 142.5 +INTS13 ASUN, C12orf11, FLJ10637, Mat89Bb, NET48, SPATA30 ENSG00000064102 Integrator complex subunit 13 12 26905181-26938326 Predicted intracellular proteins Evidence at protein level HPA039543 Uncertain Liver cancer:1.17e-10 (unfavourable), Renal cancer:3.16e-6 (unfavourable) Expressed in all Expressed in all adrenal gland: 23.1 Expressed in all +TM7SF3 ENSG00000064115 Transmembrane 7 superfamily member 3 12 26973195-27014434 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA057640 Supported Nucleus
Cytosol Renal cancer:1.32e-4 (favourable) Expressed in all Expressed in all kidney: 190.9 Expressed in all +DLX3 ENSG00000064195 Distal-less homeobox 3 17 49990005-49995224 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Endometrial cancer:4.61e-4 (unfavourable) Mixed Group enriched 5 placenta: 10.7;skin: 21.9 thyroid gland: 3.1 Cell line enhanced BEWO: 131.0;SK-BR-3: 33.0 +SPA17 CT22, SP17 ENSG00000064199 Sperm autoantigenic protein 17 11 124673798-124697518 Predicted intracellular proteins Evidence at protein level HPA037568 Enhanced Approved Vesicles Endometrial cancer:1.03e-4 (favourable) Expressed in all Group enriched 7 fallopian tube: 124.1;testis: 430.2 epididymis: 38.3 Mixed +TSPAN32 PHEMX, TSSC6 ENSG00000064201 Tetraspanin 32 11 2301997-2318200 Predicted membrane proteins Evidence at protein level HPA024135 Uncertain Mixed Tissue enhanced bone marrow: 12.0;heart muscle: 7.6 lymph node: 6.3 Group enriched 7 HEL: 13.1;HL-60: 5.1;NB-4: 3.3;THP-1: 3.8;U-937: 6.9 +WISP2 CCN5, CT58, CTGF-L ENSG00000064205 WNT1 inducible signaling pathway protein 2 20 44714844-44728509 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB019273 Approved Tissue enhanced Tissue enhanced cervix, uterine: 459.5;ovary: 167.2 breast: 70.0 Cell line enhanced ASC TERT1: 71.5;HeLa: 40.1;U-2197: 313.4 +DMRT3 DMRTA3 ENSG00000064218 Doublesex and mab-3 related transcription factor 3 9 976964-991731 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA077685 Approved Tissue enhanced Tissue enriched 6 parathyroid gland: 65.3 thyroid gland: 10.4 Cell line enhanced HAP1: 1.3;HEK 293: 1.5;SCLC-21H: 1.1;THP-1: 1.8 +ST3GAL6 SIAT10, ST3GALVI ENSG00000064225 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 3 98732236-98821201 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018792 Approved Tissue enhanced Mixed liver: 28.4 Cell line enhanced RPMI-8226: 65.1;SK-MEL-30: 85.2 +ATP2C2 KIAA0703, SPCA2 ENSG00000064270 ATPase secretory pathway Ca2+ transporting 2 16 84368527-84464187 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level HPA052262, HPA075812 Approved Approved Plasma membrane
Focal adhesion sites Endometrial cancer:6.20e-6 (favourable) Mixed Tissue enhanced rectum: 38.4 skin: 30.0 Cell line enhanced MCF7: 18.7;RT4: 15.1;SK-BR-3: 24.6;T-47d: 10.4 +NGFR CD271, p75NTR, TNFRSF16 ENSG00000064300 Nerve growth factor receptor 17 49495293-49515017 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level CAB000143, CAB001995, HPA004765 Enhanced Approved Nucleoplasm
Plasma membrane Urothelial cancer:3.40e-4 (unfavourable) Expressed in all Mixed adipose tissue: 32.4 Group enriched 8 RH-30: 193.0;WM-115: 221.3 +CDON CDO, CDON1, ORCAM ENSG00000064309 Cell adhesion associated, oncogene regulated 11 125955796-126063335 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB012422, HPA017377 Uncertain Renal cancer:1.78e-7 (unfavourable), Breast cancer:1.35e-4 (favourable) Mixed Tissue enhanced thyroid gland: 75.5 ovary: 53.5 Cell line enhanced AF22: 55.0;ASC diff: 47.4;RH-30: 93.1 +TAF2 CIF150, TAF2B, TAFII150 ENSG00000064313 TATA-box binding protein associated factor 2 8 119730775-119832863 Disease related genes, Predicted intracellular proteins Evidence at protein level Endometrial cancer:2.45e-4 (unfavourable), Liver cancer:9.58e-4 (unfavourable) Expressed in all Expressed in all testis: 25.4 Expressed in all +HIPK2 ENSG00000064393 Homeodomain interacting protein kinase 2 7 139561570-139777778 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA007611 Supported Supported Nucleus Renal cancer:9.99e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 61.3 Cell line enhanced HDLM-2: 113.5 +TNPO3 IPO12, LGMD1F, MTR10A, TRN-SR, TRN-SR2 ENSG00000064419 Transportin 3 7 128954180-129055173 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039555, HPA041537 Approved Enhanced Vesicles Liver cancer:3.29e-5 (unfavourable) Expressed in all Expressed in all testis: 48.4 Expressed in all +BORCS8-MEF2B MEF2BNB-MEF2B ENSG00000064489 BORCS8-MEF2B readthrough 19 19145567-19192158 Predicted intracellular proteins Evidence at protein level HPA004734 Uncertain Not detected Mixed fallopian tube: 1.4 Cell line enhanced PC-3: 7.8;U-266/70: 6.4 +RFXANK ANKRA1, BLS, F14150_1, MGC138628, RFX-B ENSG00000064490 Regulatory factor X associated ankyrin containing protein 19 19192229-19201869 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049157, HPA053330 Approved Enhanced Nucleoplasm Expressed in all Expressed in all fallopian tube: 50.1 Expressed in all +TMEM161A FLJ20422, FLJ39645 ENSG00000064545 Transmembrane protein 161A 19 19119169-19138513 Predicted membrane proteins Evidence at protein level HPA043365 Approved Approved Cytosol Stomach cancer:2.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.7 Expressed in all +LPAR2 EDG-4, EDG4, LPA2 ENSG00000064547 Lysophosphatidic acid receptor 2 19 19623668-19628930 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA019616 Approved Renal cancer:1.61e-7 (unfavourable), Stomach cancer:1.43e-4 (favourable) Expressed in all Mixed testis: 40.7 Cell line enhanced HMC-1: 64.8 +CTSA GSL, PPGB ENSG00000064601 Cathepsin A 20 45890144-45898820 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB024930, HPA031068 Enhanced Enhanced Vesicles Liver cancer:1.95e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 243.4 Expressed in all +SUGP2 KIAA0365, SFRS14 ENSG00000064607 SURP and G-patch domain containing 2 19 18990888-19034023 Predicted intracellular proteins Evidence at protein level HPA041557, HPA061111 Enhanced Enhanced Nucleoplasm
Nuclear bodies Liver cancer:3.21e-4 (unfavourable) Expressed in all Expressed in all testis: 161.7 Expressed in all +SLC12A2 BSC, BSC2, NKCC1, PPP1R141 ENSG00000064651 Solute carrier family 12 member 2 5 128083766-128189688 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA020130, HPA063697 Approved Approved Vesicles
Plasma membrane Renal cancer:7.09e-4 (favourable), Endometrial cancer:8.60e-4 (favourable) Expressed in all Expressed in all rectum: 65.4 Expressed in all +SNX24 SBBI31 ENSG00000064652 Sorting nexin 24 5 122843439-123029354 Predicted intracellular proteins Evidence at protein level HPA044566, HPA073934 Approved Approved Vesicles Endometrial cancer:7.93e-6 (unfavourable), Renal cancer:1.28e-4 (favourable), Liver cancer:8.88e-4 (unfavourable) Expressed in all Expressed in all esophagus: 39.4 Mixed +EYA2 EAB1 ENSG00000064655 EYA transcriptional coactivator and phosphatase 2 20 46894624-47188844 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027024, HPA059291 Uncertain Supported Cytosol Endometrial cancer:4.30e-5 (favourable) Tissue enhanced Tissue enhanced cervix, uterine: 76.3 fallopian tube: 50.0 Cell line enhanced HBEC3-KT: 28.0;SCLC-21H: 68.4;U-266/70: 82.5;U-266/84: 98.8 +CNN2 ENSG00000064666 Calponin 2 19 1026581-1039068 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049095 Approved Approved Nucleoplasm
Actin filaments
Cytosol Renal cancer:4.70e-7 (unfavourable) Expressed in all Expressed in all lymph node: 208.5 Mixed +ABCA7 ABCX ENSG00000064687 ATP binding cassette subfamily A member 7 19 1040101-1065572 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041564 Enhanced Supported Golgi apparatus
Plasma membrane
Cell Junctions Endometrial cancer:1.12e-4 (favourable), Colorectal cancer:7.26e-4 (unfavourable) Expressed in all Mixed spleen: 25.3 Cell line enhanced HMC-1: 52.2 +SNCAIP SYPH1 ENSG00000064692 Synuclein alpha interacting protein 5 122311354-122464219 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064687 Uncertain Supported Nucleoplasm
Cytoplasmic bodies Mixed Tissue enhanced endometrium: 29.8;ovary: 43.3 cervix, uterine: 25.8 Cell line enhanced AF22: 4.9;BJ hTERT+: 3.9;RPMI-8226: 3.7 +DDX20 DP103, GEMIN3 ENSG00000064703 DEAD-box helicase 20 1 111755245-111768016 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA005516, CAB015427 Enhanced Supported Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:6.35e-6 (unfavourable), Colorectal cancer:9.85e-5 (favourable) Expressed in all Tissue enriched 10 testis: 130.7 parathyroid gland: 12.6 Expressed in all +BTBD1 ENSG00000064726 BTB domain containing 1 15 83016422-83067354 Predicted intracellular proteins Evidence at protein level HPA067671 Enhanced Renal cancer:6.21e-7 (favourable) Expressed in all Expressed in all skeletal muscle: 109.7 Expressed in all +FAR2 FLJ10462, MLSTD1, SDR10E2 ENSG00000064763 Fatty acyl-CoA reductase 2 12 29149103-29340980 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015884 Approved Approved Nucleoli
Golgi apparatus Renal cancer:4.93e-4 (unfavourable) Expressed in all Mixed epididymis: 43.9 Cell line enhanced HUVEC TERT2: 69.5 +BCAS1 AIBC1, NABC1 ENSG00000064787 Breast carcinoma amplified sequence 1 20 53936777-54070594 Predicted intracellular proteins Evidence at protein level CAB033558, HPA051816, HPA054745 Enhanced Approved Vesicles Mixed Tissue enhanced cerebral cortex: 108.7;stomach: 155.8 rectum: 80.7 Group enriched 6 RT4: 143.2;SK-BR-3: 277.9 +POU1F1 GHF-1, PIT1, POU1F1a ENSG00000064835 POU class 1 homeobox 1 3 87259404-87276587 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041646, HPA050624 Enhanced Not detected Not detected adrenal gland,cerebral cortex,gallbladder,skeletal muscle,spleen,thyroid gland: 0.1 Not detected +CHI3L2 YKL-39, YKL39 ENSG00000064886 Chitinase 3 like 2 1 111200771-111243440 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005443 Uncertain Renal cancer:8.59e-7 (unfavourable), Glioma:1.55e-4 (unfavourable), Head and neck cancer:2.19e-4 (favourable) Tissue enriched Tissue enhanced appendix: 152.3 tonsil: 103.1 Cell line enhanced ASC diff: 62.1;MOLT-4: 277.3;U-698: 51.9 +SBNO2 FLJ00173, KIAA0963, Sno, Stno ENSG00000064932 Strawberry notch homolog 2 19 1107636-1174283 Predicted intracellular proteins Evidence at protein level HPA041867 Approved Renal cancer:7.98e-8 (unfavourable) Expressed in all Mixed adipose tissue: 13.9 Cell line enhanced HDLM-2: 61.0 +PMS1 MLH2, PMSL1 ENSG00000064933 PMS1 homolog 1, mismatch repair system component 2 189784085-189877629 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB010233, HPA031013 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:1.86e-6 (unfavourable), Liver cancer:2.38e-6 (unfavourable), Urothelial cancer:3.73e-4 (favourable) Expressed in all Expressed in all testis: 85.0 Expressed in all +HMG20B BRAF25, BRAF35, HMGX2, HMGXB2, SMARCE1r, SOXL ENSG00000064961 High mobility group 20B 19 3572777-3579088 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050220, HPA053157, HPA069832 Approved Enhanced Nucleoplasm Endometrial cancer:1.72e-7 (favourable), Urothelial cancer:2.89e-5 (favourable) Expressed in all Expressed in all prostate: 70.1 Expressed in all +CALCRL CGRPR, CRLR ENSG00000064989 Calcitonin receptor like receptor 2 187343129-187448460 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA008070, HPA046515 Uncertain Supported Plasma membrane Expressed in all Tissue enhanced lung: 114.3 adipose tissue: 76.8 Cell line enhanced HUVEC TERT2: 145.5;RPTEC TERT1: 30.7;TIME: 20.7 +TAF11 TAF2I, TAFII28 ENSG00000064995 TATA-box binding protein associated factor 11 6 34877778-34888089 Predicted intracellular proteins Evidence at protein level HPA029326, HPA049127 Supported Nucleoplasm
Golgi apparatus Ovarian cancer:5.87e-4 (favourable) Expressed in all Expressed in all testis: 54.8 Expressed in all +ANKS1A ANKS1, KIAA0229 ENSG00000064999 Ankyrin repeat and sterile alpha motif domain containing 1A 6 34889265-35091413 Predicted intracellular proteins Evidence at protein level HPA036768, HPA036769 Approved Approved Nucleoplasm
Cytosol Renal cancer:8.05e-5 (favourable), Head and neck cancer:7.48e-4 (favourable) Expressed in all Expressed in all placenta: 39.2 Expressed in all +AP3D1 ADTD ENSG00000065000 Adaptor related protein complex 3 delta 1 subunit 19 2100988-2164465 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA074408 Approved Cytosol Renal cancer:2.61e-6 (favourable), Liver cancer:9.23e-4 (unfavourable) Expressed in all Expressed in all testis: 60.7 Expressed in all +ZNF76 D6S229E, Zfp523, ZNF523 ENSG00000065029 Zinc finger protein 76 6 35258909-35295985 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030090, HPA030091 Approved Approved Nucleoplasm
Cytosol Ovarian cancer:1.18e-4 (favourable), Pancreatic cancer:5.09e-4 (favourable) Expressed in all Expressed in all thyroid gland: 34.7 Expressed in all +SLC9A3R2 E3KARP, NHERF-2, SIP-1, TKA-1 ENSG00000065054 SLC9A3 regulator 2 16 2025356-2039026 Predicted intracellular proteins, Transporters Evidence at protein level HPA001672, HPA066520 Enhanced Supported Plasma membrane Endometrial cancer:1.03e-4 (favourable) Expressed in all Mixed lung: 160.8 Cell line enhanced MCF7: 234.6;PC-3: 259.8 +NTHL1 NTH1, OCTS3 ENSG00000065057 Nth like DNA glycosylase 1 16 2039815-2047866 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB025152 Supported Expressed in all Expressed in all fallopian tube: 21.3 Expressed in all +UHRF1BP1 C6orf107, dJ349A12.1, FLJ20302, ICBP90 ENSG00000065060 UHRF1 binding protein 1 6 34792015-34883138 Predicted intracellular proteins Evidence at protein level HPA032099, HPA032100 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Liver cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all testis: 22.2 Expressed in all +GNAI3 87U6 ENSG00000065135 G protein subunit alpha i3 1 109548611-109618321 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022099, HPA042141 Approved Supported Nucleus
Nucleoli
Centrosome Liver cancer:5.30e-6 (unfavourable), Colorectal cancer:1.62e-4 (favourable), Renal cancer:4.34e-4 (unfavourable), Ovarian cancer:4.59e-4 (favourable) Expressed in all Mixed esophagus: 7.9 Expressed in all +IPO5 IMB3, KPNB3, MGC2068, Pse1, RANBP5 ENSG00000065150 Importin 5 13 97953658-98024297 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB009110, HPA040983, HPA056548 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 384.5 Expressed in all +OAT HOGA ENSG00000065154 Ornithine aminotransferase 10 124397303-124418976 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033576, HPA040098, HPA064742 Enhanced Supported Nucleoplasm
Mitochondria Expressed in all Expressed in all small intestine: 859.8 Mixed +WDR3 DIP2, FLJ12796, UTP12 ENSG00000065183 WD repeat domain 3 1 117929720-117966542 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027509, HPA054354 Supported Nucleus
Nuclear membrane
Nucleoli Liver cancer:7.33e-5 (unfavourable), Pancreatic cancer:8.82e-4 (unfavourable) Expressed in all Expressed in all testis: 22.3 Expressed in all +PKN2 Pak-2, PRK2, PRKCL2, STK7 ENSG00000065243 Protein kinase N2 1 88684222-88836255 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034861, HPA057913 Approved Supported Nucleoplasm
Plasma membrane
Intermediate filaments
Cytosol Colorectal cancer:5.67e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 48.8 Expressed in all +WDR18 Ipi3 ENSG00000065268 WD repeat domain 18 19 984271-998438 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050193, HPA050200 Approved Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 17.9 Expressed in all +TRAM2 KIAA0057 ENSG00000065308 Translocation associated membrane protein 2 6 52497402-52576915 Predicted membrane proteins Evidence at protein level HPA035092, HPA057925 Approved Approved Cytosol Renal cancer:1.41e-9 (unfavourable), Endometrial cancer:1.88e-4 (unfavourable) Expressed in all Expressed in all placenta: 52.1 Expressed in all +NTN1 NTN1L ENSG00000065320 Netrin 1 17 9021542-9244000 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA056419 Approved Mixed Mixed esophagus: 21.2 Cell line enhanced BEWO: 26.7;T-47d: 15.6;U-2 OS: 15.2;U-251 MG: 18.3;WM-115: 12.7 +GLP2R ENSG00000065325 Glucagon like peptide 2 receptor 17 9822206-9892102 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB022690, HPA049244 Supported Supported Plasma membrane Tissue enhanced Tissue enhanced gallbladder: 19.3 duodenum: 10.1 Cell line enhanced A549: 15.1;HeLa: 54.7;SiHa: 8.7 +MCM10 CNA43, DNA43, PRO2249 ENSG00000065328 Minichromosome maintenance 10 replication initiation factor 10 13161554-13211104 Predicted intracellular proteins Evidence at protein level HPA045899, HPA071952 Approved Supported Nucleus
Nucleoli Mixed Mixed bone marrow: 5.9 Mixed +DGKA DAGK, DAGK1, DGK-alpha ENSG00000065357 Diacylglycerol kinase alpha 12 55927319-55954027 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041645, HPA045462 Approved Approved Nucleoplasm
Vesicles
Mitochondria Renal cancer:1.66e-5 (unfavourable) Expressed in all Mixed skin: 97.4 Cell line enhanced HBEC3-KT: 93.1;hTERT-HME1: 102.8 +ERBB3 HER3, LCCS2 ENSG00000065361 Erb-b2 receptor tyrosine kinase 3 12 56079857-56103505 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025331, HPA045396 Uncertain Approved Plasma membrane
Actin filaments Expressed in all Mixed small intestine: 86.8 Cell line enhanced Hep G2: 79.5;SK-BR-3: 77.6;SK-MEL-30: 109.7;T-47d: 108.2;WM-115: 145.7 +ROPN1 CT91, ODF6, ROPN1A, ropporin ENSG00000065371 Rhophilin associated tail protein 1 3 123968521-123992178 Predicted intracellular proteins Evidence at protein level HPA052530 Supported Group enriched Tissue enriched 9 testis: 223.8 breast: 24.1 Cell line enriched 7 SK-MEL-30: 21.4 +ANKRD44 PP6-ARS-B ENSG00000065413 Ankyrin repeat domain 44 2 196967017-197311173 Predicted intracellular proteins Evidence at protein level HPA030122, HPA056549 Approved Approved Nuclear speckles
Mitochondria Mixed Mixed lymph node: 42.7 Cell line enhanced HDLM-2: 43.2;HMC-1: 30.0 +KARS DFNB89, KARS1, KARS2 ENSG00000065427 Lysyl-tRNA synthetase 16 75627474-75648643 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041345, HPA041550 Enhanced Supported Cytosol Head and neck cancer:8.84e-6 (unfavourable) Expressed in all Expressed in all testis: 178.6 Expressed in all +ADAT1 ENSG00000065457 Adenosine deaminase, tRNA specific 1 16 75596981-75623300 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040713, HPA040903 Approved Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 91.2 Expressed in all +PDIA5 FLJ30401, PDIR ENSG00000065485 Protein disulfide isomerase family A member 5 3 123067062-123225227 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030353, HPA030355 Enhanced Supported Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus Renal cancer:8.09e-11 (unfavourable), Endometrial cancer:4.55e-4 (favourable) Expressed in all Mixed placenta: 70.8 Mixed +TBC1D22B C6orf197, dJ744I24.2, FLJ20337 ENSG00000065491 TBC1 domain family member 22B 6 37257772-37332970 Predicted intracellular proteins Evidence at protein level HPA027908, HPA027909, HPA027910 Uncertain Uncertain Nucleoplasm
Cytosol Endometrial cancer:8.15e-5 (unfavourable) Expressed in all Expressed in all testis: 18.8 Expressed in all +NDUFB4 B15 ENSG00000065518 NADH:ubiquinone oxidoreductase subunit B4 3 120596309-120602500 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051739 Enhanced Supported Nuclear membrane
Mitochondria Urothelial cancer:1.79e-4 (favourable) Expressed in all Expressed in all adrenal gland: 364.4 Expressed in all +SPEN KIAA0929, MINT, RBM15C, SHARP ENSG00000065526 Spen family transcriptional repressor 1 15847864-15940460 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015825, HPA050257 Supported Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 39.0 Expressed in all +MYLK MLCK, MLCK1, MYLK1, smMLCK ENSG00000065534 Myosin light chain kinase 3 123610049-123884331 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB020789, HPA031677, HPA048055 Enhanced Enhanced Plasma membrane
Actin filaments Renal cancer:2.04e-6 (unfavourable), Urothelial cancer:4.46e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 3002.5 Cell line enhanced BJ: 144.8;BJ hTERT+: 209.1;fHDF/TERT166: 165.3;RPTEC TERT1: 207.7 +ZC3H15 LEREPO4 ENSG00000065548 Zinc finger CCCH-type containing 15 2 186486156-186509363 Predicted intracellular proteins Evidence at protein level HPA031099, HPA031100, HPA031101 Enhanced Enhanced Cytosol Liver cancer:1.48e-7 (unfavourable), Cervical cancer:6.45e-5 (unfavourable), Ovarian cancer:3.98e-4 (favourable), Pancreatic cancer:9.75e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 78.5 Expressed in all +MAP2K4 JNKK1, MEK4, MKK4, PRKMK4, SERK1 ENSG00000065559 Mitogen-activated protein kinase kinase 4 17 12020824-12143830 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007751, HPA060074 Enhanced Approved Nucleoplasm
Cell Junctions Expressed in all Expressed in all cerebral cortex: 64.0 Expressed in all +TMEM206 C1orf75, FLJ10874 ENSG00000065600 Transmembrane protein 206 1 212363931-212414901 Predicted membrane proteins Evidence at protein level HPA008540 Uncertain Liver cancer:3.71e-5 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 25.4 kidney: 10.7 Expressed in all +SNAP91 AP180, CALM, KIAA0656 ENSG00000065609 Synaptosome associated protein 91 6 83552880-83709691 Predicted intracellular proteins Evidence at protein level CAB009745, HPA029632, HPA029633 Enhanced Uncertain Centrosome
Cytosol Tissue enhanced Tissue enriched 7 cerebral cortex: 152.1 testis: 22.5 Group enriched 16 SCLC-21H: 27.9;SH-SY5Y: 15.7 +SLK KIAA0204, se20-9, STK2 ENSG00000065613 STE20 like kinase 10 103967201-104029233 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015757 Approved Approved Plasma membrane
Cytosol Pancreatic cancer:2.77e-5 (unfavourable), Renal cancer:3.95e-5 (favourable) Expressed in all Expressed in all esophagus: 61.0 Expressed in all +CYB5R4 b5+b5R, dJ676J13.1, NCB5OR ENSG00000065615 Cytochrome b5 reductase 4 6 83859643-83967424 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018992 Approved Expressed in all Expressed in all testis: 22.4 Expressed in all +COL17A1 BP180, BPAG2 ENSG00000065618 Collagen type XVII alpha 1 chain 10 104031286-104086002 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043673, HPA052963 Enhanced Supported Golgi apparatus
Plasma membrane Breast cancer:1.38e-4 (favourable), Pancreatic cancer:1.86e-4 (unfavourable) Tissue enhanced Tissue enriched 14 skin: 769.3 placenta: 53.1 Group enriched 6 CAPAN-2: 175.9;HaCaT: 403.2;HBEC3-KT: 525.2;hTCEpi: 673.0;hTERT-HME1: 604.3 +GSTO2 ENSG00000065621 Glutathione S-transferase omega 2 10 104268873-104304945 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048141 Approved Approved Nucleus
Nucleoli Renal cancer:7.10e-7 (favourable) Mixed Mixed testis: 36.1 Cell line enhanced CAPAN-2: 45.6;hTCEpi: 32.1;hTERT-HME1: 36.7;T-47d: 36.0 +SEC61A2 FLJ10578 ENSG00000065665 Sec61 translocon alpha 2 subunit 10 12129637-12169961 Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:2.22e-16 (unfavourable), Pancreatic cancer:1.08e-5 (favourable), Urothelial cancer:8.75e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 51.3 testis: 32.5 Expressed in all +PRKCQ ENSG00000065675 Protein kinase C theta 10 6427143-6580301 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065279, HPA073098 Enhanced Microtubule organizing center Thyroid cancer:5.27e-4 (unfavourable) Mixed Tissue enhanced skeletal muscle: 43.0 thyroid gland: 25.0 Cell line enhanced HEL: 50.9;MOLT-4: 34.7 +TLE2 ESG, ESG2, FLJ41188, GRG2 ENSG00000065717 Transducin like enhancer of split 2 19 2997638-3047635 Predicted intracellular proteins Evidence at protein level HPA049103 Approved Supported Nuclear bodies
Focal adhesion sites Pancreatic cancer:2.39e-6 (favourable), Renal cancer:9.49e-6 (favourable), Endometrial cancer:2.51e-4 (favourable), Urothelial cancer:8.88e-4 (favourable) Expressed in all Mixed seminal vesicle: 39.6 Cell line enhanced AN3-CA: 39.6;RT4: 27.6 +ASB1 ASB-1 ENSG00000065802 Ankyrin repeat and SOCS box containing 1 2 238426742-238452250 Predicted intracellular proteins Evidence at protein level HPA003508 Uncertain Approved Nucleoplasm Endometrial cancer:4.89e-5 (unfavourable), Pancreatic cancer:1.56e-4 (favourable), Liver cancer:5.37e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 20.1 Expressed in all +FAM107B C10orf45, FLJ45505, HITS, MGC11034 ENSG00000065809 Family with sequence similarity 107 member B 10 14518557-14774897 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039661, HPA058814, HPA073195 Approved Supported Nucleoplasm Expressed in all Expressed in all lymph node: 179.9 Expressed in all +ME1 ENSG00000065833 Malic enzyme 1 6 83210389-83431071 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006493 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.81e-7 (unfavourable), Liver cancer:4.57e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 54.1 Cell line enhanced CACO-2: 113.5 +TBC1D1 KIAA1108, TBC, TBC1 ENSG00000065882 TBC1 domain family member 1 4 37891087-38139175 Predicted intracellular proteins, Transporters Evidence at protein level HPA041816, HPA058158 Approved Uncertain Nucleoli Renal cancer:1.47e-8 (favourable), Lung cancer:5.22e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 251.2 Expressed in all +CDK13 CDC2L, CDC2L5, CHED, KIAA1791 ENSG00000065883 Cyclin dependent kinase 13 7 39950037-40097134 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059241 Uncertain Supported Nuclear speckles Expressed in all Expressed in all parathyroid gland: 33.5 Expressed in all +MTHFD2 ENSG00000065911 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 74198562-74217565 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB003684, HPA049657 Approved Renal cancer:1.11e-16 (unfavourable), Endometrial cancer:2.07e-5 (unfavourable), Glioma:8.47e-5 (favourable) Expressed in all Expressed in all appendix: 39.6 Expressed in all +SLC9A7 NHE7 ENSG00000065923 Solute carrier family 9 member A7 X 46599252-46759172 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA048938, HPA075385 Approved Supported Vesicles Endometrial cancer:8.58e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 14.4 Mixed +FOXJ2 FHX ENSG00000065970 Forkhead box J2 12 8032703-8055503 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008723 Approved Supported Nucleus
Nucleoli fibrillar center Renal cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.7 Mixed +YBX1 BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1 ENSG00000065978 Y-box binding protein 1 1 42682427-42702349 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005875, HPA040304, HPA057159 Supported Enhanced Vesicles
Cytosol Liver cancer:9.87e-10 (unfavourable), Renal cancer:3.59e-7 (unfavourable) Expressed in all Expressed in all testis: 1542.9 Expressed in all +PDE4A DPDE2 ENSG00000065989 Phosphodiesterase 4A 19 10416773-10469631 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB017632, HPA043310, HPA076091 Uncertain Supported Plasma membrane Expressed in all Mixed parathyroid gland: 34.0 Cell line enhanced HMC-1: 32.2 +PPP2R5A B56A, PR61A ENSG00000066027 Protein phosphatase 2 regulatory subunit B'alpha 1 212285537-212361863 Predicted intracellular proteins Evidence at protein level HPA059288 Supported Cytosol Expressed in all Expressed in all lung: 86.5 Expressed in all +CTNNA2 CAP-R, CT114 ENSG00000066032 Catenin alpha 2 2 79185231-80648861 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037175 Enhanced Group enriched Group enriched 12 cerebral cortex: 111.6;epididymis: 81.5;testis: 32.2 adrenal gland: 6.3 Cell line enhanced AF22: 7.0;Karpas-707: 5.9;NTERA-2: 6.7;SCLC-21H: 4.5;SH-SY5Y: 11.4 +ELAVL1 Hua, HUR, MelG ENSG00000066044 ELAV like RNA binding protein 1 19 7958579-8005659 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005256, HPA046298 Approved Supported Nucleus
Nucleoli
Cytosol Ovarian cancer:4.93e-4 (favourable) Expressed in all Expressed in all testis: 81.9 Expressed in all +TIE1 JTK14, TIE ENSG00000066056 Tyrosine kinase with immunoglobulin like and EGF like domains 1 1 43300993-43323108 Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Expressed in all Tissue enhanced placenta: 70.6 lung: 40.1 Cell line enhanced EFO-21: 100.1;HUVEC TERT2: 199.8;TIME: 171.4 +DIP2B FLJ34278, KIAA1463 ENSG00000066084 Disco interacting protein 2 homolog B 12 50504985-50748667 Predicted intracellular proteins Evidence at protein level HPA038472, HPA046133, HPA056045 Enhanced Approved Endoplasmic reticulum Breast cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 31.0 Expressed in all +SMARCD1 BAF60A, CRACD1, Rsc6p ENSG00000066117 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 12 50084972-50100712 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA004101 Supported Approved Nucleoplasm
Vesicles Liver cancer:2.53e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 86.5 Expressed in all +KDM4A JHDM3A, JMJD2, JMJD2A, KIAA0677, TDRD14A ENSG00000066135 Lysine demethylase 4A 1 43650158-43705515 Predicted intracellular proteins Evidence at protein level HPA007610 Uncertain Supported Nucleoli fibrillar center Liver cancer:1.39e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 31.2 Expressed in all +NFYC CBF-C, NF-YC ENSG00000066136 Nuclear transcription factor Y subunit gamma 1 40691648-40771603 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055011 Supported Nucleoplasm Renal cancer:1.24e-4 (favourable), Liver cancer:7.24e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 58.6 Expressed in all +ZMYND12 DKFZp434N2435 ENSG00000066185 Zinc finger MYND-type containing 12 1 42430329-42456267 Predicted intracellular proteins Evidence at transcript level Renal cancer:1.11e-5 (favourable) Mixed Tissue enhanced fallopian tube: 23.4;testis: 51.8 epididymis: 8.7 Cell line enhanced HSkMC: 1.6;SK-MEL-30: 1.5;WM-115: 1.4 +SLC9A3 NHE3 ENSG00000066230 Solute carrier family 9 member A3 5 473310-524332 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA036493, HPA036669 Enhanced Supported Plasma membrane Melanoma:8.49e-4 (unfavourable) Mixed Tissue enhanced colon: 80.9;gallbladder: 66.1;small intestine: 72.6 kidney: 57.3 Cell line enhanced HDLM-2: 30.4 +NGEF ARHGEF27 ENSG00000066248 Neuronal guanine nucleotide exchange factor 2 232878686-233013272 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008160 Approved Uncertain Plasma membrane
Cytosol Mixed Tissue enhanced adrenal gland: 66.5;cerebral cortex: 151.4 duodenum: 42.8 Cell line enhanced A-431: 46.9;HDLM-2: 42.0;PC-3: 52.8;T-47d: 30.2 +ASPM ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5 ENSG00000066279 Abnormal spindle microtubule assembly 1 197084128-197146694 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017816 Approved Approved Plasma membrane
Cytosol Liver cancer:1.25e-4 (unfavourable), Endometrial cancer:1.97e-4 (unfavourable), Pancreatic cancer:2.40e-4 (unfavourable), Lung cancer:2.41e-4 (unfavourable) Mixed Mixed bone marrow: 9.3 Mixed +CD84 hCD84, mCD84, SLAMF5 ENSG00000066294 CD84 molecule 1 160541095-160579516 CD markers, Predicted membrane proteins Evidence at protein level HPA070502 Enhanced Expressed in all Tissue enhanced lymph node: 28.4 appendix: 26.8 Cell line enhanced Daudi: 17.1;HEL: 41.2;HMC-1: 44.1;U-698: 22.1 +ELOVL1 Ssc1 ENSG00000066322 ELOVL fatty acid elongase 1 1 43363397-43368074 Enzymes, Predicted membrane proteins Evidence at protein level CAB033426, HPA056557 Approved Approved Endoplasmic reticulum Liver cancer:2.79e-7 (unfavourable), Cervical cancer:3.63e-5 (unfavourable), Pancreatic cancer:8.51e-4 (unfavourable) Expressed in all Expressed in all skin: 156.7 Expressed in all +SPI1 OF, PU.1, SFPI1, SPI-1, SPI-A ENSG00000066336 Spi-1 proto-oncogene 11 47354860-47378576 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level CAB004079, HPA044653 Enhanced Supported Nucleoplasm Renal cancer:2.07e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 212.5 Cell line enhanced HL-60: 125.6;HMC-1: 245.7;NB-4: 167.8;THP-1: 137.9;U-937: 90.6 +ZNRD1 HTEX-6, hZR14, RPA12, tctex-6 ENSG00000066379 Zinc ribbon domain containing 1 6 30058899-30064909 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA055074, HPA077979 Supported Supported Nucleoli fibrillar center Renal cancer:2.17e-7 (unfavourable), Urothelial cancer:2.75e-5 (favourable) Expressed in all Mixed lymph node: 5.9 Mixed +MPPED2 239FB, C11orf8, D11S302E, dJ1024C24.1, dJ873F21.1, FAM1B, Hs.46638 ENSG00000066382 Metallophosphoesterase domain containing 2 11 30384493-30586872 Predicted intracellular proteins Evidence at protein level HPA062575 Approved Nucleoli
Vesicles
Mitochondria Mixed Tissue enhanced cervix, uterine: 38.7;thyroid gland: 43.7 prostate: 20.9 Cell line enhanced HaCaT: 19.2;HAP1: 13.2;RT4: 7.3;SH-SY5Y: 7.2 +CLDN18 SFTPJ ENSG00000066405 Claudin 18 3 137998735-138033655 Predicted membrane proteins Evidence at protein level CAB013010, CAB013243, HPA018446 Enhanced Group enriched Group enriched 85 lung: 361.8;stomach: 689.7 heart muscle: 6.1 Not detected +ZBTB11 ZNF-U69274, ZNF913 ENSG00000066422 Zinc finger and BTB domain containing 11 3 101648889-101677495 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA015328, HPA024138 Approved Enhanced Nucleoplasm Endometrial cancer:7.49e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 23.4 Expressed in all +ATXN3 ATX3, JOS, MJD, SCA3 ENSG00000066427 Ataxin 3 14 92038652-92106621 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB021976, HPA024123, HPA069338 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Mixed Mixed testis: 18.6 Expressed in all +GOLGA5 golgin-84, GOLIM5, ret-II, rfg5 ENSG00000066455 Golgin A5 14 92794231-92839963 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000992, HPA063876 Enhanced Supported Supported Golgi apparatus Expressed in all Expressed in all epididymis: 65.3 Expressed in all +FGFR2 BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25 ENSG00000066468 Fibroblast growth factor receptor 2 10 121478334-121598458 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB010886, HPA035305, HPA056562 Uncertain Approved Vesicles Cervical cancer:8.79e-4 (favourable), Head and neck cancer:9.32e-4 (favourable) Expressed in all Mixed skin: 129.4 Cell line enhanced AN3-CA: 169.6;BEWO: 58.8;HAP1: 61.4;NTERA-2: 58.4 +LRRC40 FLJ20331 ENSG00000066557 Leucine rich repeat containing 40 1 70144805-70205620 Predicted intracellular proteins Evidence at protein level HPA026564 Approved Approved Nucleoli Colorectal cancer:4.54e-4 (favourable) Expressed in all Expressed in all testis: 21.7 Expressed in all +ISOC1 CGI-111 ENSG00000066583 Isochorismatase domain containing 1 5 129094751-129114028 Predicted intracellular proteins Evidence at protein level HPA070307 Approved Endoplasmic reticulum
Vesicles Expressed in all Expressed in all endometrium: 175.5 Expressed in all +EML1 ELP79, EMAP, EMAPL, HuEMAP ENSG00000066629 Echinoderm microtubule associated protein like 1 14 99737693-99942060 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB033137, HPA049105 Uncertain Expressed in all Mixed parathyroid gland: 51.3 Cell line enhanced HDLM-2: 84.2;U-2197: 100.9 +TRMT11 C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1 ENSG00000066651 TRNA methyltransferase 11 homolog 6 125986430-126039276 Predicted intracellular proteins Evidence at protein level HPA030473 Approved Nuclear bodies Expressed in all Expressed in all thyroid gland: 16.5 Mixed +THUMPD1 FLJ20274, Tan1 ENSG00000066654 THUMP domain containing 1 16 20702816-20742084 Predicted intracellular proteins Evidence at protein level HPA027851 Approved Approved Cytosol Renal cancer:8.52e-8 (favourable), Colorectal cancer:2.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 68.5 Expressed in all +MSANTD3 C9orf30, MGC17337 ENSG00000066697 Myb/SANT DNA binding domain containing 3 9 100427156-100451711 Predicted intracellular proteins Evidence at protein level HPA062662 Approved Nucleoplasm Renal cancer:3.22e-7 (unfavourable), Liver cancer:3.23e-6 (unfavourable), Head and neck cancer:6.66e-5 (unfavourable), Lung cancer:3.56e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 23.4 Expressed in all +KIF26A DKFZP434N178, KIAA1236 ENSG00000066735 Kinesin family member 26A 14 104138723-104180894 Predicted intracellular proteins Evidence at protein level HPA046882, HPA060346 Uncertain Approved Nucleus
Plasma membrane
Cytosol Renal cancer:7.78e-4 (unfavourable) Group enriched Mixed adipose tissue: 5.0 Cell line enhanced HeLa: 18.9;MCF7: 18.8;NTERA-2: 20.8;REH: 17.1;SCLC-21H: 22.6;SH-SY5Y: 41.6 +ATG2B C14orf103, FLJ10242 ENSG00000066739 Autophagy related 2B 14 96279202-96363870 Predicted intracellular proteins Evidence at protein level HPA000880, HPA001427, HPA019665 Approved Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 17.1 Expressed in all +ARFGEF1 ARFGEP1, BIG1, DKFZP434L057, p200 ENSG00000066777 ADP ribosylation factor guanine nucleotide exchange factor 1 8 67173511-67343677 Predicted intracellular proteins Evidence at protein level HPA023399, HPA023822 Supported Approved Enhanced Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:2.48e-4 (favourable), Breast cancer:8.76e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 59.5 Expressed in all +ACSM2B ACSM2, HXMA, HYST1046 ENSG00000066813 Acyl-CoA synthetase medium-chain family member 2B 16 20536226-20576427 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA057699 Supported Liver cancer:3.31e-4 (favourable) Group enriched Group enriched 136 kidney: 426.7;liver: 262.0 thyroid gland: 2.5 Cell line enhanced AF22: 2.8;Hep G2: 3.7 +ZFAT KIAA1485, ZFAT1, ZNF406 ENSG00000066827 Zinc finger and AT-hook domain containing 8 134477788-134713049 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020989, HPA063592 Enhanced Approved Nucleoplasm
Nuclear bodies Expressed in all Group enriched 6 kidney: 10.5;placenta: 44.3 testis: 4.3 Mixed +MTFR1 CHPPR, FAM54A2, KIAA0009 ENSG00000066855 Mitochondrial fission regulator 1 8 65644734-65771261 Predicted intracellular proteins Evidence at protein level HPA023152, HPA056120 Uncertain Supported Mitochondria
Cytosol Breast cancer:4.06e-4 (unfavourable), Thyroid cancer:5.21e-4 (unfavourable) Expressed in all Expressed in all testis: 35.2 Expressed in all +STAG3 ENSG00000066923 Stromal antigen 3 7 100177563-100221488 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049106, HPA058330 Enhanced Cervical cancer:8.45e-4 (favourable) Mixed Tissue enriched 5 testis: 130.2 fallopian tube: 23.9 Group enriched 6 BEWO: 49.1;HMC-1: 56.4;U-698: 13.2 +FECH ENSG00000066926 Ferrochelatase 18 57548283-57586772 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA044100, HPA048177 Approved Renal cancer:2.38e-10 (favourable) Expressed in all Expressed in all bone marrow: 93.3 Expressed in all +MYO9A FLJ11061, FLJ13244, MGC71859 ENSG00000066933 Myosin IXA 15 71822289-72118577 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039812, HPA040071 Approved Approved Plasma membrane Renal cancer:2.14e-4 (favourable) Mixed Tissue enhanced testis: 51.5 thyroid gland: 22.1 Expressed in all +DDX3Y DBY ENSG00000067048 DEAD-box helicase 3, Y-linked Y 12904108-12920478 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001648, HPA005631 Uncertain Approved Supported Nucleus
Cytosol Head and neck cancer:4.70e-5 (favourable) Mixed Tissue enhanced testis: 128.6 prostate: 54.0 Cell line enhanced HEL: 139.0 +PFKP PFK-C, PFKF ENSG00000067057 Phosphofructokinase, platelet 10 3066333-3137712 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018257, HPA056484 Uncertain Supported Cytosol Liver cancer:8.72e-6 (unfavourable), Head and neck cancer:1.55e-4 (unfavourable) Expressed in all Expressed in all testis: 285.1 Mixed +IDI1 ENSG00000067064 Isopentenyl-diphosphate delta isomerase 1 10 1039908-1049170 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039169 Approved Renal cancer:1.46e-4 (favourable) Expressed in all Expressed in all breast: 244.8 Expressed in all +SP100 ENSG00000067066 SP100 nuclear antigen 2 230415942-230544090 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016707, HPA017384 Enhanced Supported Nucleus
Nuclear bodies Renal cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 139.6 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 274.7 +KLF6 BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9 ENSG00000067082 Kruppel like factor 6 10 3775996-3785281 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB013529, HPA069585 Supported Approved Nucleus
Nucleoli fibrillar center
Vesicles
Cytosol Renal cancer:2.28e-4 (favourable) Expressed in all Expressed in all thyroid gland: 323.6 Expressed in all +PLPP1 LPP1, PAP-2a, PPAP2A ENSG00000067113 Phospholipid phosphatase 1 5 55424854-55535050 Enzymes, Predicted membrane proteins Evidence at protein level CAB033331, HPA047815 Enhanced Supported Plasma membrane Stomach cancer:5.77e-4 (unfavourable), Liver cancer:6.06e-4 (favourable) Expressed in all Mixed prostate: 339.9 Cell line enhanced ASC diff: 295.0;HMC-1: 201.8 +NEO1 HsT17534, IGDCC2, NGN, NTN1R2 ENSG00000067141 Neogenin 1 15 73051710-73305206 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB009320, HPA027804, HPA027805, HPA027806 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Renal cancer:4.39e-4 (favourable) Expressed in all Mixed parathyroid gland: 102.7 Mixed +TRAM1 TRAM, TRAMP ENSG00000067167 Translocation associated membrane protein 1 8 70573442-70608387 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA023929 Approved Cervical cancer:2.06e-4 (unfavourable), Renal cancer:7.79e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 317.7 Expressed in all +PHKA1 PHKA ENSG00000067177 Phosphorylase kinase regulatory subunit alpha 1 X 72578814-72714319 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001081 Enhanced Approved Vesicles Endometrial cancer:6.84e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 40.1;skeletal muscle: 35.5 adrenal gland: 15.6 Mixed +TNFRSF1A CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60 ENSG00000067182 TNF receptor superfamily member 1A 12 6328757-6342114 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004102, CAB010309 Approved Renal cancer:2.70e-7 (unfavourable), Head and neck cancer:3.68e-4 (unfavourable), Endometrial cancer:8.22e-4 (favourable) Expressed in all Expressed in all smooth muscle: 141.2 Mixed +CACNB1 CACNLB1 ENSG00000067191 Calcium voltage-gated channel auxiliary subunit beta 1 17 39173456-39197703 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA023343 Approved Endometrial cancer:3.80e-4 (unfavourable) Mixed Group enriched 6 cerebral cortex: 46.7;skeletal muscle: 108.5 skin: 12.3 Mixed +EVI5 NB4S ENSG00000067208 Ecotropic viral integration site 5 1 92508696-92792404 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027339, HPA053724 Approved Supported Golgi apparatus
Vesicles Expressed in all Mixed testis: 18.0 Mixed +STOML1 FLJ36370, hUNC-24, SLP-1, STORP ENSG00000067221 Stomatin like 1 15 73978923-73994622 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042353 Approved Approved Cytosol Expressed in all Expressed in all cerebral cortex: 43.7 Expressed in all +PKM OIP3, PK3, PKM2, THBP1 ENSG00000067225 Pyruvate kinase, muscle 15 72199029-72231822 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB019421, HPA029501 Uncertain Enhanced Cytosol Liver cancer:2.74e-6 (unfavourable), Pancreatic cancer:5.17e-5 (unfavourable), Head and neck cancer:1.30e-4 (unfavourable), Lung cancer:2.85e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 1492.3 Expressed in all +DHX29 DDX29 ENSG00000067248 DExH-box helicase 29 5 55256245-55307722 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038317, HPA038318 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 39.2 Expressed in all +DNTTIP2 ERBP, HSU15552, TdIF2 ENSG00000067334 Deoxynucleotidyltransferase terminal interacting protein 2 1 93866283-93879918 Predicted intracellular proteins Evidence at protein level HPA044502, HPA053707 Enhanced Enhanced Nucleoli Liver cancer:1.90e-6 (unfavourable), Renal cancer:7.80e-5 (unfavourable) Expressed in all Mixed bone marrow: 10.5 Expressed in all +METTL22 C16orf68, FLJ12433, MGC2654 ENSG00000067365 Methyltransferase like 22 16 8621683-8649654 Predicted intracellular proteins Evidence at protein level HPA040803, HPA059882, HPA074173 Uncertain Supported Nucleus
Nucleoli Renal cancer:2.79e-8 (unfavourable) Expressed in all Mixed testis: 15.9 Expressed in all +TP53BP1 53BP1, p202, TDRD30 ENSG00000067369 Tumor protein p53 binding protein 1 15 43403061-43510728 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004083, HPA008788, HPA022133 Supported Enhanced Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 51.2 Expressed in all +TRO KIAA1114, MAGE-D3, MAGED3 ENSG00000067445 Trophinin X 54920462-54931431 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053358 Approved Nucleus
Nucleoli fibrillar center Endometrial cancer:4.41e-5 (unfavourable), Pancreatic cancer:1.93e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 30.0 endometrium: 22.2 Cell line enhanced AF22: 36.8;SCLC-21H: 29.3;SH-SY5Y: 35.5 +RRP15 CGI-115, KIAA0507 ENSG00000067533 Ribosomal RNA processing 15 homolog 1 218285287-218337983 Predicted intracellular proteins Evidence at protein level HPA024639 Approved Approved Nucleus
Nucleoli
Mitochondria Liver cancer:4.26e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 7.7 Expressed in all +RHOA ARH12, ARHA, Rho12, RhoA, RHOH12 ENSG00000067560 Ras homolog family member A 3 49359145-49412998 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB005052 Approved Renal cancer:3.21e-6 (favourable), Colorectal cancer:3.08e-4 (favourable), Liver cancer:9.15e-4 (unfavourable) Expressed in all Expressed in all lung: 592.0 Expressed in all +DHX8 DDX8, HRH1, PRP22, PRPF22 ENSG00000067596 DEAH-box helicase 8 17 43483865-43544463 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049285 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 55.0 Expressed in all +PRKCZ PKC2 ENSG00000067606 Protein kinase C zeta 1 2050470-2185395 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021851 Enhanced Approved Plasma membrane
Cytosol Renal cancer:1.64e-9 (favourable) Expressed in all Tissue enhanced cerebral cortex: 99.7 placenta: 62.3 Cell line enhanced BEWO: 45.1 +ZFY ZNF911 ENSG00000067646 Zinc finger protein, Y-linked Y 2935281-2982506 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001748, HPA071863 Uncertain Approved Nucleoplasm
Nucleoli Head and neck cancer:3.58e-5 (favourable) Mixed Mixed testis: 12.8 Mixed +IARS2 FLJ10326 ENSG00000067704 Isoleucyl-tRNA synthetase 2, mitochondrial 1 220094102-220148041 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA024212, HPA024594, HPA024596 Enhanced Enhanced Mitochondria Pancreatic cancer:9.24e-5 (unfavourable), Cervical cancer:1.04e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 144.3 Expressed in all +SYT1 P65, SVP65, SYT ENSG00000067715 Synaptotagmin 1 12 78863993-79452008 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA008394, HPA064788 Enhanced Supported Mixed Tissue enriched 13 cerebral cortex: 476.5 smooth muscle: 36.7 Cell line enhanced hTERT-HME1: 29.8;LHCN-M2: 26.5;SH-SY5Y: 32.1;WM-115: 28.3 +NAV3 KIAA0938, POMFIL1 ENSG00000067798 Neuron navigator 3 12 77324641-78213008 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA032111, HPA032112, CAB037063 Uncertain Approved Nuclear membrane
Cytosol Mixed Tissue enhanced cerebral cortex: 27.2;ovary: 24.6 spleen: 12.3 Cell line enhanced hTEC/SVTERT24-B: 46.2;WM-115: 38.6 +IDH3G ENSG00000067829 Isocitrate dehydrogenase 3 (NAD(+)) gamma X 153785766-153794523 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000425, HPA002017 Enhanced Enhanced Mitochondria Renal cancer:5.73e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 64.9 Expressed in all +ROGDI FLJ22386 ENSG00000067836 Rogdi homolog 16 4796968-4802950 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041000 Uncertain Renal cancer:2.67e-5 (favourable), Pancreatic cancer:9.71e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 39.2 Mixed +PDZD4 FLJ34125, KIAA1444, LNX5, LU1, PDZK4, PDZRN4L ENSG00000067840 PDZ domain containing 4 X 153802166-153830565 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA003878 Enhanced Pancreatic cancer:2.96e-5 (favourable) Tissue enhanced Tissue enriched 9 cerebral cortex: 123.5 seminal vesicle: 13.7 Cell line enhanced AF22: 24.1;RH-30: 16.8;SCLC-21H: 34.7;SH-SY5Y: 30.4;U-2 OS: 14.9 +ATP2B3 CFAP39, CLA2, PMCA3, SCAX1 ENSG00000067842 ATPase plasma membrane Ca2+ transporting 3 X 153517676-153582939 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA001583 Enhanced Uncertain Golgi apparatus
Plasma membrane Not detected Group enriched 8 adrenal gland: 12.1;cerebral cortex: 19.0 fallopian tube: 2.0 Cell line enhanced SCLC-21H: 11.7;SH-SY5Y: 3.1;THP-1: 1.7;U-937: 1.9 +ROCK1 p160ROCK ENSG00000067900 Rho associated coiled-coil containing protein kinase 1 18 20946906-21111851 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004562, HPA007567, HPA045639 Approved Pancreatic cancer:9.93e-4 (unfavourable) Expressed in all Mixed bone marrow: 12.3 Expressed in all +CBFB PEBP2B ENSG00000067955 Core-binding factor beta subunit 16 67029116-67101058 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038852 Uncertain Approved Nucleus
Cytosol Renal cancer:2.89e-8 (unfavourable), Liver cancer:2.83e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 97.5 Expressed in all +PDK3 ENSG00000067992 Pyruvate dehydrogenase kinase 3 X 24465221-24539837 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046583, HPA072492 Approved Supported Nucleoli
Mitochondria Liver cancer:2.76e-4 (unfavourable) Expressed in all Mixed testis: 24.9 Mixed +HYAL2 LuCa-2, LUCA2 ENSG00000068001 Hyaluronoglucosaminidase 2 3 50317790-50322906 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA036436 Uncertain Expressed in all Expressed in all spleen: 214.2 Expressed in all +HDAC4 BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288 ENSG00000068024 Histone deacetylase 4 2 239048168-239401654 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB004431, HPA048723 Approved Supported Nucleoplasm
Cytosol Pancreatic cancer:1.13e-4 (favourable), Ovarian cancer:6.33e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 19.3 Cell line enhanced MOLT-4: 40.5 +RASSF1 123F2, NORE2A, RDA32, REH3P21 ENSG00000068028 Ras association domain family member 1 3 50329782-50340980 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA040735 Approved Renal cancer:8.58e-5 (unfavourable), Head and neck cancer:2.60e-4 (favourable), Cervical cancer:2.64e-4 (favourable), Liver cancer:9.77e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 51.8 Expressed in all +FGFR3 ACH, CD333, CEK2, JTK4 ENSG00000068078 Fibroblast growth factor receptor 3 4 1793307-1808872 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB004231, HPA067204 Enhanced Supported Endoplasmic reticulum Endometrial cancer:3.77e-4 (unfavourable) Expressed in all Tissue enriched 7 skin: 333.1 cerebral cortex: 49.4 Cell line enhanced CACO-2: 41.4;Hep G2: 56.1;NTERA-2: 37.4;RT4: 81.0 +IFI35 IFP35 ENSG00000068079 Interferon induced protein 35 17 43006725-43014456 Predicted intracellular proteins Evidence at protein level HPA045946 Approved Nucleoplasm
Cytosol Renal cancer:4.03e-5 (unfavourable), Breast cancer:1.41e-4 (favourable) Expressed in all Expressed in all spleen: 44.0 Cell line enhanced BJ hTERT+ SV40 Large T+: 190.3;BJ hTERT+ SV40 Large T+ RasG12V: 291.3 +HEATR6 ABC1, FLJ22087 ENSG00000068097 HEAT repeat containing 6 17 60043194-60078931 Predicted intracellular proteins Evidence at protein level HPA030789, HPA062157 Uncertain Approved Mitochondria Liver cancer:5.02e-6 (unfavourable), Endometrial cancer:2.03e-4 (unfavourable), Renal cancer:6.73e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 13.3 Cell line enhanced MCF7: 80.3 +COASY CoASY, DPCK, NBP, PPAT ENSG00000068120 Coenzyme A synthase 17 42561467-42566277 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA022875, HPA022912, HPA023273 Approved Approved Nucleoplasm
Cytosol Liver cancer:7.54e-5 (unfavourable), Endometrial cancer:2.15e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 60.1 Expressed in all +PLEKHH3 FLJ21019 ENSG00000068137 Pleckstrin homology, MyTH4 and FERM domain containing H3 17 42667914-42676994 Predicted intracellular proteins Evidence at protein level HPA046234 Uncertain Approved Golgi apparatus Renal cancer:9.62e-5 (unfavourable) Expressed in all Expressed in all skin: 11.6 Cell line enhanced T-47d: 46.9 +MEF2A RSRFC4, RSRFC9 ENSG00000068305 Myocyte enhancer factor 2A 15 99565417-99716466 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004499, HPA046597 Approved Supported Nucleoplasm Renal cancer:6.93e-4 (favourable), Stomach cancer:7.96e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 68.5 Expressed in all +OTUD5 DKFZp761A052, DUBA ENSG00000068308 OTU deubiquitinase 5 X 48922028-48958386 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017375 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Lung cancer:1.48e-4 (favourable), Pancreatic cancer:8.20e-4 (favourable), Cervical cancer:9.57e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 69.9 Group enriched 8 U-266/70: 1128.2;U-266/84: 277.1 +TFE3 bHLHe33, TFEA ENSG00000068323 Transcription factor binding to IGHM enhancer 3 X 49028726-49043486 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023881 Approved Supported Nucleoplasm
Cytosol Renal cancer:2.19e-8 (unfavourable), Liver cancer:6.03e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 24.4 Expressed in all +TBC1D25 OATL1 ENSG00000068354 TBC1 domain family member 25 X 48539457-48562609 Predicted intracellular proteins Evidence at protein level HPA029197 Approved Supported Expressed in all Expressed in all parathyroid gland: 12.9 Expressed in all +ACSL4 ACS4, FACL4, LACS4, MRX63, MRX68 ENSG00000068366 Acyl-CoA synthetase long-chain family member 4 X 109624244-109733403 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000286, HPA005552 Enhanced Approved Golgi apparatus
Mitochondria Urothelial cancer:5.73e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 70.7 Cell line enhanced HMC-1: 324.7 +INPP5A 5PTASE ENSG00000068383 Inositol polyphosphate-5-phosphatase A 10 132537820-132783480 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012285, HPA066549 Enhanced Approved Cytosol Renal cancer:3.15e-4 (favourable), Breast cancer:7.47e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 60.9 Expressed in all +GPKOW GPATC5, GPATCH5, Spp2, T54 ENSG00000068394 G-patch domain and KOW motifs X 49113389-49123801 Predicted intracellular proteins Evidence at protein level HPA000287, HPA001894 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all cerebral cortex: 30.8 Expressed in all +GRIPAP1 DKFZp434P0630, GRASP-1, GRASP1, KIAA1167, MPMGp800B12492Q3 ENSG00000068400 GRIP1 associated protein 1 X 48973720-49002264 Predicted intracellular proteins Evidence at protein level HPA000282, HPA000615 Enhanced Approved Vesicles
Cytosol Renal cancer:3.92e-7 (unfavourable), Urothelial cancer:4.63e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 68.5 Expressed in all +FTSJ1 CDLIV, JM23, MRX44, MRX9, SPB1, TRM7, TRMT7 ENSG00000068438 FtsJ RNA methyltransferase homolog 1 (E. coli) X 48476021-48486364 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002718 Approved Approved Cytosol Renal cancer:5.24e-10 (unfavourable), Liver cancer:1.74e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 24.7 Expressed in all +PRR11 FLJ11029 ENSG00000068489 Proline rich 11 17 59155499-59204705 Predicted intracellular proteins Evidence at protein level HPA023923, HPA052376 Uncertain Approved Endoplasmic reticulum Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.35e-7 (unfavourable), Lung cancer:1.79e-4 (unfavourable), Endometrial cancer:1.90e-4 (unfavourable), Pancreatic cancer:6.18e-4 (unfavourable) Expressed in all Mixed lymph node: 11.2 Mixed +REEP1 C2orf23, FLJ13110, SPG31, Yip2a ENSG00000068615 Receptor accessory protein 1 2 86213993-86338083 Disease related genes, Predicted membrane proteins Evidence at protein level HPA058061 Enhanced Mixed Tissue enhanced testis: 92.3 cerebral cortex: 54.1 Cell line enhanced BEWO: 65.9;SCLC-21H: 38.4 +ATP11A ATPIH, ATPIS, KIAA1021 ENSG00000068650 ATPase phospholipid transporting 11A 13 112690329-112887168 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA035583, HPA035584 Approved Enhanced Vesicles Renal cancer:7.44e-4 (favourable) Expressed in all Expressed in all lung: 59.1 Mixed +POLR1A DKFZP586M0122, FLJ21915, RPA1, RPO1-4 ENSG00000068654 RNA polymerase I subunit A 2 86020216-86106155 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB010145, HPA031513, HPA049700 Supported Supported Nucleus
Nucleoli fibrillar center Liver cancer:3.70e-9 (unfavourable), Ovarian cancer:3.37e-4 (unfavourable), Thyroid cancer:8.41e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 12.3 Expressed in all +LAPTM4A HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp ENSG00000068697 Lysosomal protein transmembrane 4 alpha 2 20032650-20052028 Predicted membrane proteins Evidence at protein level HPA031402, HPA031404, HPA068554 Approved Approved Golgi apparatus
Vesicles
Plasma membrane Pancreatic cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 635.0 Expressed in all +TTC7A KIAA1140, TTC7 ENSG00000068724 Tetratricopeptide repeat domain 7A 2 46916157-47076137 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036781, HPA036782 Enhanced Ovarian cancer:1.36e-4 (unfavourable) Expressed in all Tissue enhanced testis: 40.9 lung: 17.7 Expressed in all +IP6K2 IHPK2 ENSG00000068745 Inositol hexakisphosphate kinase 2 3 48688003-48740353 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007532, HPA070811 Approved Approved Nucleus
Nucleoli fibrillar center
Cell Junctions Breast cancer:1.25e-4 (favourable), Urothelial cancer:1.83e-4 (favourable), Lung cancer:2.95e-4 (favourable) Expressed in all Expressed in all epididymis: 131.1 Expressed in all +STON1-GTF2A1L SALF ENSG00000068781 STON1-GTF2A1L readthrough 2 48529925-48776517 Predicted intracellular proteins Evidence at protein level HPA005715 Uncertain Not detected Mixed endometrium,smooth muscle: 3.6 Cell line enhanced ASC diff: 1.5;ASC TERT1: 1.4;HSkMC: 1.0 +SRBD1 FLJ10379 ENSG00000068784 S1 RNA binding domain 1 2 45388680-45612165 Predicted intracellular proteins Evidence at protein level HPA030567, HPA030568 Approved Approved Mitochondria
Cytosol Expressed in all Mixed parathyroid gland: 31.8 Expressed in all +KIF2A HK2, KIF2 ENSG00000068796 Kinesin family member 2A 5 62306162-62537249 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004715, HPA004716 Approved Enhanced Nucleus
Nucleoli
Centrosome Liver cancer:3.17e-6 (unfavourable), Renal cancer:3.81e-5 (unfavourable), Colorectal cancer:1.70e-4 (favourable), Head and neck cancer:5.45e-4 (favourable) Expressed in all Expressed in all testis: 91.8 Expressed in all +RASGRP2 CALDAG-GEFI ENSG00000068831 RAS guanyl releasing protein 2 11 64726911-64745456 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA015667 Approved Renal cancer:1.38e-4 (unfavourable) Mixed Tissue enhanced lymph node: 122.0;spleen: 107.0 bone marrow: 94.3 Cell line enhanced HEL: 90.3;HL-60: 145.9;NB-4: 219.4;REH: 94.2;THP-1: 72.4 +PSME4 KIAA0077, PA200 ENSG00000068878 Proteasome activator subunit 4 2 53864067-53970840 Predicted intracellular proteins Evidence at protein level HPA060922 Approved Supported Nucleoplasm Liver cancer:4.84e-4 (unfavourable), Endometrial cancer:8.99e-4 (unfavourable) Expressed in all Expressed in all testis: 78.1 Expressed in all +IFT80 KIAA1374, WDR56 ENSG00000068885 Intraflagellar transport 80 3 160256986-160399880 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035868 Uncertain Expressed in all Expressed in all parathyroid gland: 46.5 Expressed in all +SIRT2 SIR2L ENSG00000068903 Sirtuin 2 19 38878555-38899862 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB004573, HPA011165 Approved Approved Nucleus
Nucleoli
Cytosol Endometrial cancer:7.20e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 83.9 Expressed in all +ERLEC1 C2orf30, CL25084, ERLECTIN, XTP3-B, XTP3TPB ENSG00000068912 Endoplasmic reticulum lectin 1 2 53787044-53818819 Predicted secreted proteins, Transporters Evidence at protein level HPA031501, HPA031502, HPA031503 Enhanced Expressed in all Expressed in all thyroid gland: 121.9 Expressed in all +PPP2R5B B56B, FLJ35411, PR61B ENSG00000068971 Protein phosphatase 2 regulatory subunit B'beta 11 64917553-64934473 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036607 Approved Liver cancer:3.24e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 59.7 Expressed in all +PYGM ENSG00000068976 Glycogen phosphorylase, muscle associated 11 64746389-64760297 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA056003 Enhanced Mixed Tissue enriched 32 skeletal muscle: 2831.9 esophagus: 89.0 Cell line enhanced HSkMC: 2.6 +PAGE1 CT16.3, GAGE-9, GAGEB1, PAGE-1 ENSG00000068985 PAGE family member 1 X 49687450-49695993 Predicted intracellular proteins Evidence at protein level HPA003473 Enhanced Approved Nucleus
Nucleoli fibrillar center
Mitochondria Tissue enhanced Tissue enriched 168 testis: 25.1 epididymis,placenta: 0.1 Group enriched 7 A-431: 161.4;Karpas-707: 98.5;U-266/84: 157.3 +PITX1 BFT, POTX, PTX1 ENSG00000069011 Paired like homeodomain 1 5 135027735-135034813 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008743 Approved Supported Nucleoli Tissue enhanced Tissue enriched 5 esophagus: 211.7 salivary gland: 38.5 Cell line enhanced CACO-2: 116.7;K-562: 103.4;T-47d: 154.3 +TRPC7 ENSG00000069018 Transient receptor potential cation channel subfamily C member 7 5 136213320-136365537 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level CAB022592, HPA031126 Uncertain Uncertain Actin filaments
Focal adhesion sites Not detected Not detected testis: 0.7 Not detected +MAST4 KIAA0303 ENSG00000069020 Microtubule associated serine/threonine kinase family member 4 5 66596361-67169595 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000544 Approved Approved Nucleoplasm
Cytosol Head and neck cancer:5.18e-5 (favourable) Expressed in all Mixed parathyroid gland: 47.7 Cell line enhanced HDLM-2: 40.1 +ADGRF5 DKFZp564O1923, GPR116, KIAA0758 ENSG00000069122 Adhesion G protein-coupled receptor F5 6 46852512-46954943 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Renal cancer:8.84e-5 (favourable) Expressed in all Tissue enhanced lung: 157.8 adipose tissue: 76.2 Group enriched 8 HUVEC TERT2: 20.7;TIME: 61.2 +SDK2 FLJ10832, KIAA1514 ENSG00000069188 Sidekick cell adhesion molecule 2 17 73334384-73644089 Predicted membrane proteins Evidence at protein level HPA014725 Approved Nucleoplasm Mixed Tissue enhanced cervix, uterine: 9.0;testis: 18.6 fallopian tube: 4.0 Cell line enhanced AF22: 13.8;BEWO: 11.0;U-2 OS: 5.0 +ADAM7 EAPI, GP-83 ENSG00000069206 ADAM metallopeptidase domain 7 8 24440930-24526970 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008879 Enhanced Group enriched Tissue enriched 199 epididymis: 4534.6 seminal vesicle: 22.7 Group enriched 23 BEWO: 2.3;NB-4: 3.9;RPMI-8226: 1.1;SH-SY5Y: 1.9 +NUP133 FLJ10814 ENSG00000069248 Nucleoporin 133 1 229440260-229508341 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA059767 Approved Supported Nuclear membrane Expressed in all Expressed in all parathyroid gland: 33.1 Expressed in all +NUCKS1 NUCKS ENSG00000069275 Nuclear casein kinase and cyclin dependent kinase substrate 1 1 205712819-205750276 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062351, HPA063843 Supported Supported Nucleus
Nucleoli Endometrial cancer:1.41e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 179.2 Expressed in all +VPS35 FLJ10752, MEM3, PARK17 ENSG00000069329 VPS35, retromer complex component 16 46656132-46689518 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040802 Enhanced Supported Endosomes
Lysosomes Liver cancer:2.10e-6 (unfavourable), Renal cancer:9.75e-5 (favourable), Colorectal cancer:7.74e-4 (favourable) Expressed in all Mixed parathyroid gland: 15.8 Expressed in all +DNAJA2 CPR3, DNAJ, DNJ3, HIRIP4 ENSG00000069345 DnaJ heat shock protein family (Hsp40) member A2 16 46955362-46973788 Predicted intracellular proteins Evidence at protein level HPA049789, HPA060538 Approved Approved Nucleoli
Intermediate filaments
Cytosol Renal cancer:1.19e-9 (favourable), Head and neck cancer:2.81e-4 (unfavourable) Expressed in all Expressed in all testis: 42.0 Expressed in all +BCL3 BCL4, D19S37 ENSG00000069399 B-cell CLL/lymphoma 3 19 44747705-44760044 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002051, HPA047514 Approved Supported Nucleoplasm
Vesicles
Midbody Renal cancer:3.13e-14 (unfavourable), Melanoma:3.74e-4 (favourable), Glioma:5.58e-4 (unfavourable), Breast cancer:9.67e-4 (favourable) Expressed in all Expressed in all appendix: 30.1 Cell line enhanced HDLM-2: 55.4;SiHa: 65.8 +KCNAB2 AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B ENSG00000069424 Potassium voltage-gated channel subfamily A regulatory beta subunit 2 1 5991466-6101193 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001975 Enhanced Renal cancer:3.50e-5 (unfavourable) Tissue enriched Tissue enhanced cerebral cortex: 145.9 bone marrow: 74.8 Cell line enhanced HL-60: 277.8;U-937: 287.1 +ABCC9 CMD1O, SUR2 ENSG00000069431 ATP binding cassette subfamily C member 9 12 21797401-21942529 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA007279 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.85e-5 (unfavourable) Mixed Mixed smooth muscle: 37.2 Cell line enhanced ASC diff: 18.7;CACO-2: 21.7;HSkMC: 23.7;U-138 MG: 27.1 +GAL GAL-GMAP, GALN, GLNN, GMAP ENSG00000069482 Galanin and GMAP prepropeptide 11 68683779-68691175 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA049864 Enhanced Supported Approved Golgi apparatus
Vesicles Endometrial cancer:1.22e-4 (unfavourable), Lung cancer:8.17e-4 (unfavourable) Mixed Tissue enhanced appendix: 18.1;smooth muscle: 12.1 colon: 5.2 Cell line enhanced CACO-2: 193.9;K-562: 111.4;NB-4: 277.5;SH-SY5Y: 179.1 +CLEC2D CLAX, LLT1, OCIL ENSG00000069493 C-type lectin domain family 2 member D 12 9664969-9699555 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017649, HPA047584 Uncertain Uncertain Nucleoplasm
Golgi apparatus Renal cancer:5.85e-11 (unfavourable), Urothelial cancer:1.68e-7 (favourable), Cervical cancer:1.37e-4 (favourable) Expressed in all Tissue enhanced lymph node: 63.4 tonsil: 38.0 Cell line enhanced Daudi: 48.6;HDLM-2: 49.6;U-698: 71.5 +FUNDC1 MGC51029 ENSG00000069509 FUN14 domain containing 1 X 44523639-44543001 Predicted intracellular proteins Evidence at protein level HPA038773 Uncertain Urothelial cancer:2.58e-4 (favourable), Testis cancer:8.35e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 30.6 Mixed +MAOB ENSG00000069535 Monoamine oxidase B X 43766611-43882447 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA002328, CAB037200 Enhanced Approved Nucleoli
Mitochondria Expressed in all Mixed seminal vesicle: 215.4 Group enriched 9 Hep G2: 28.1;SiHa: 82.8 +RORA NR1F1, ROR1, ROR2, ROR3, RZRA ENSG00000069667 RAR related orphan receptor A 15 60488284-61229319 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009861 Approved Renal cancer:5.42e-6 (favourable) Mixed Expressed in all skin: 76.3 Cell line enhanced Karpas-707: 52.5;U-266/70: 31.7;U-266/84: 43.2 +DRD4 ENSG00000069696 Dopamine receptor D4 11 637293-640706 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Not detected skin: 0.3 Not detected +TGFBR3 betaglycan, BGCAN ENSG00000069702 Transforming growth factor beta receptor 3 1 91680343-91906335 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008257, CAB018971 Supported Uncertain Cytosol Thyroid cancer:3.14e-4 (unfavourable), Endometrial cancer:3.36e-4 (unfavourable), Head and neck cancer:4.84e-4 (favourable), Renal cancer:4.99e-4 (favourable) Expressed in all Expressed in all ovary: 99.9 Cell line enhanced ASC diff: 152.4;ASC TERT1: 75.3;U-2197: 71.9 +KIAA1107 ENSG00000069712 KIAA1107 1 92166985-92184723 Predicted intracellular proteins Evidence at protein level HPA024216 Supported Mixed Group enriched 9 cerebral cortex: 45.9;testis: 10.7 adrenal gland,epididymis: 3.2 Mixed +PLA2G10 GXPLA2 ENSG00000069764 Phospholipase A2 group X 16 14672545-14694669 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA041893 Uncertain Endometrial cancer:5.74e-5 (favourable) Mixed Tissue enhanced colon: 6.9;rectum: 6.5;stomach: 10.4 duodenum: 2.2 Cell line enhanced CAPAN-2: 1.3 +HES2 bHLHb40 ENSG00000069812 Hes family bHLH transcription factor 2 1 6412418-6424670 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA039462 Uncertain Mixed Tissue enhanced skin: 17.0 placenta: 9.8 Cell line enhanced BEWO: 19.0;HaCaT: 33.0;HBEC3-KT: 23.1;TIME: 44.9 +ATP1B3 CD298, FLJ29027 ENSG00000069849 ATPase Na+/K+ transporting subunit beta 3 3 141876124-141926514 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB020697, HPA048963 Enhanced Supported Plasma membrane Liver cancer:6.32e-6 (unfavourable), Renal cancer:1.29e-5 (unfavourable), Endometrial cancer:5.19e-5 (favourable) Expressed in all Expressed in all skin: 310.1 Expressed in all +NEDD4 KIAA0093, MGC176705, NEDD4-1, RPF1 ENSG00000069869 Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 15 55826922-55993746 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level CAB001991, HPA039883, CAB072833 Approved Approved Cytosol Renal cancer:3.74e-6 (unfavourable), Lung cancer:5.14e-4 (unfavourable) Expressed in all Mixed placenta: 22.4 Mixed +PIGB ENSG00000069943 Phosphatidylinositol glycan anchor biosynthesis class B 15 55318960-55355648 Predicted membrane proteins Evidence at protein level HPA039929 Uncertain Uncertain Plasma membrane
Cytosol Expressed in all Mixed parathyroid gland: 22.8 Expressed in all +MAPK6 ERK3, HsT17250, p97MAPK, PRKM6 ENSG00000069956 Mitogen-activated protein kinase 6 15 51952106-52067372 Enzymes, Predicted intracellular proteins Evidence at protein level CAB005184, HPA030262 Approved Approved Enhanced Cytosol Expressed in all Expressed in all testis: 53.0 Expressed in all +GNB5 GB5 ENSG00000069966 G protein subunit beta 5 15 52115105-52191369 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB032353, HPA041942, HPA044198 Uncertain Approved Nuclear speckles
Centrosome
Rods & Rings Renal cancer:3.32e-11 (favourable), Endometrial cancer:1.47e-6 (favourable) Expressed in all Mixed parathyroid gland: 74.6 Expressed in all +RAB27A GS2, HsT18676, RAB27, RAM ENSG00000069974 RAB27A, member RAS oncogene family 15 55202966-55319113 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001333, CAB034046 Enhanced Renal cancer:1.67e-4 (unfavourable), Breast cancer:2.56e-4 (favourable) Expressed in all Mixed stomach: 115.1 Cell line enhanced K-562: 212.3 +HDHD5 CECR5 ENSG00000069998 Haloacid dehalogenase like hydrolase domain containing 5 22 17137511-17165287 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005548 Approved Approved Mitochondria Expressed in all Expressed in all duodenum: 26.7 Mixed +UFD1L UFD1 ENSG00000070010 Ubiquitin fusion degradation 1 like (yeast) 22 19449910-19479215 Predicted intracellular proteins, Transporters Evidence at protein level HPA030287, HPA030288, HPA073425 Approved Enhanced Endoplasmic reticulum Renal cancer:4.50e-8 (unfavourable), Liver cancer:2.59e-4 (unfavourable) Expressed in all Expressed in all epididymis: 66.0 Expressed in all +LRP6 ADCAD2 ENSG00000070018 LDL receptor related protein 6 12 12116025-12267012 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB004490, HPA029925 Enhanced Expressed in all Mixed parathyroid gland: 16.4 Mixed +GUCY2C GUC2C, STAR ENSG00000070019 Guanylate cyclase 2C 12 14612632-14696585 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA037655, HPA073759 Uncertain Uncertain Vesicles Liver cancer:1.37e-5 (unfavourable) Group enriched Group enriched 13 colon: 37.0;duodenum: 68.7;rectum: 45.4;small intestine: 73.2 appendix: 4.4 Cell line enhanced AN3-CA: 1.2;CAPAN-2: 1.4;SiHa: 1.6 +SCT ENSG00000070031 Secretin 11 626431-627143 Predicted secreted proteins Evidence at protein level HPA050961 Enhanced Colorectal cancer:3.70e-4 (unfavourable) Mixed Group enriched 6 duodenum: 34.9;small intestine: 7.8 spleen: 3.4 Cell line enhanced HSkMC: 1.1 +PHRF1 KIAA1542, PPP1R125, RNF221 ENSG00000070047 PHD and ring finger domains 1 11 576486-612222 Predicted intracellular proteins Evidence at protein level HPA019867, HPA062933 Uncertain Liver cancer:6.00e-5 (unfavourable) Expressed in all Mixed endometrium: 4.5 Cell line enhanced EFO-21: 13.5;Hep G2: 16.4;MOLT-4: 31.6;SCLC-21H: 13.1;U-138 MG: 20.9 +IKBKAP DYS, ELP1, IKAP, IKI3, TOT1 ENSG00000070061 Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 9 108867517-108934116 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB021340, HPA049677, HPA050686 Approved Supported Nucleoplasm
Cytosol Breast cancer:1.57e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 76.5 Expressed in all +NUCB2 NEFA ENSG00000070081 Nucleobindin 2 11 17208153-17349974 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008395, HPA008530, CAB015931 Approved Approved Enhanced Golgi apparatus Endometrial cancer:8.27e-6 (favourable), Renal cancer:3.94e-5 (unfavourable), Ovarian cancer:1.98e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 733.1 Expressed in all +PFN2 ENSG00000070087 Profilin 2 3 149964904-150050788 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035611, CAB037073 Enhanced Liver cancer:2.19e-7 (unfavourable), Endometrial cancer:2.93e-4 (unfavourable), Head and neck cancer:3.42e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 419.6 Mixed +PTPN3 PTPH1 ENSG00000070159 Protein tyrosine phosphatase, non-receptor type 3 9 109375466-109498313 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038343, HPA046728 Approved Renal cancer:1.22e-15 (favourable), Endometrial cancer:1.52e-4 (favourable), Breast cancer:6.71e-4 (unfavourable) Mixed Mixed skin: 35.8 Mixed +SPTB ENSG00000070182 Spectrin beta, erythrocytic 14 64746283-64879883 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003394, HPA003398, CAB015169, CAB016232 Enhanced Uncertain Golgi apparatus
Cytosol Mixed Tissue enhanced bone marrow: 38.3;skeletal muscle: 43.1 heart muscle: 15.1 Cell line enhanced HEL: 35.6;K-562: 43.0;U-937: 11.1 +DAPP1 BAM32 ENSG00000070190 Dual adaptor of phosphotyrosine and 3-phosphoinositides 1 4 99816833-99870154 Predicted intracellular proteins Evidence at protein level CAB033822, HPA046074 Approved Mixed Mixed lymph node: 51.1 Cell line enhanced HDLM-2: 80.2;RPMI-8226: 64.7;U-698: 45.0 +FGF10 ENSG00000070193 Fibroblast growth factor 10 5 44303544-44389706 Disease related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB010315 Uncertain Tissue enriched Tissue enhanced ovary: 41.4 adipose tissue: 16.9 Cell line enriched 9 AF22: 51.3 +SLC44A1 CD92, CDW92, CHTL1, CTL1 ENSG00000070214 Solute carrier family 44 member 1 9 105244622-105439171 CD markers, Predicted membrane proteins, Transporters Evidence at protein level HPA064714 Supported Nucleoplasm
Mitochondria Renal cancer:1.85e-4 (favourable), Lung cancer:4.49e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 107.5 Expressed in all +TMEM260 C14orf101, FLJ20392 ENSG00000070269 Transmembrane protein 260 14 56488354-56650606 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003502 Uncertain Approved Nucleus
Focal adhesion sites
Cytosol Lung cancer:7.11e-4 (favourable) Expressed in all Tissue enhanced cervix, uterine: 63.5 thyroid gland: 14.1 Expressed in all +SMG6 C17orf31, EST1A, KIAA0732, SMG-6 ENSG00000070366 SMG6, nonsense mediated mRNA decay factor 17 2059839-2303771 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042932 Approved Supported Nucleoli
Cytosol Renal cancer:1.30e-6 (favourable) Expressed in all Expressed in all ovary: 47.3 Expressed in all +EXOC5 SEC10, SEC10L1, SEC10P ENSG00000070367 Exocyst complex component 5 14 57200507-57269008 Predicted intracellular proteins, Transporters Evidence at protein level HPA060837 Approved Expressed in all Mixed testis: 20.7 Expressed in all +CLTCL1 CHC22, CLH22, CLTCL, CLTD ENSG00000070371 Clathrin heavy chain like 1 22 19179473-19291716 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA075795 Approved Vesicles Mixed Tissue enhanced skeletal muscle: 24.1;testis: 49.4 bone marrow: 10.4 Cell line enhanced HMC-1: 56.9 +FGF22 ENSG00000070388 Fibroblast growth factor 22 19 639879-644371 Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Not detected Tissue enhanced skin: 8.5 cerebral cortex: 2.0 Cell line enhanced AN3-CA: 1.8 +FSTL3 FLRG, FSRP ENSG00000070404 Follistatin like 3 19 676365-683399 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB024899, HPA045378 Approved Approved Nucleoplasm Lung cancer:4.61e-7 (unfavourable), Ovarian cancer:1.65e-4 (unfavourable), Colorectal cancer:3.01e-4 (unfavourable), Endometrial cancer:3.03e-4 (unfavourable) Expressed in all Expressed in all placenta: 260.8 Expressed in all +DGCR2 DGS-C, IDD, KIAA0163, LAN, SEZ-12 ENSG00000070413 DiGeorge syndrome critical region gene 2 22 19036282-19122454 Predicted membrane proteins Evidence at protein level HPA000873, HPA075929 Uncertain Approved Nucleoplasm
Nuclear bodies Renal cancer:8.72e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 57.9 Expressed in all +RNF126 FLJ20552 ENSG00000070423 Ring finger protein 126 19 647526-663277 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043050 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 38.2 Expressed in all +MNT bHLHd3, MAD6, MXD6, ROX ENSG00000070444 MAX network transcriptional repressor 17 2384060-2401118 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059532, HPA067578 Enhanced Nucleoplasm Expressed in all Expressed in all cerebral cortex: 15.2 Expressed in all +ZXDC FLJ13861, MGC11349 ENSG00000070476 ZXD family zinc finger C 3 126437601-126475919 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049593 Supported Nucleoli
Vesicles Liver cancer:2.27e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 25.4 Expressed in all +JMJD6 KIAA0585, PTDSR, PTDSR1 ENSG00000070495 Arginine demethylase and lysine hydroxylase 17 76712832-76726799 Predicted intracellular proteins Evidence at protein level CAB004548, HPA059156 Supported Supported Nucleoplasm Renal cancer:7.59e-7 (unfavourable), Liver cancer:5.75e-6 (unfavourable), Pancreatic cancer:5.71e-4 (favourable) Expressed in all Expressed in all bone marrow: 81.0 Expressed in all +POLB ENSG00000070501 DNA polymerase beta 8 42338454-42371808 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011616, HPA049104 Enhanced Approved Vesicles Renal cancer:2.15e-5 (unfavourable), Endometrial cancer:1.46e-4 (unfavourable), Urothelial cancer:5.65e-4 (favourable) Expressed in all Expressed in all testis: 92.7 Expressed in all +ST6GALNAC1 SIAT7A, ST6GalNAcI ENSG00000070526 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 17 76624761-76643838 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014975 Uncertain Head and neck cancer:2.54e-5 (favourable) Mixed Tissue enhanced colon: 162.6;rectum: 235.5 cervix, uterine: 90.7 Cell line enhanced EFO-21: 9.1;HaCaT: 9.7;HEL: 16.1;K-562: 48.8 +WIPI1 ATG18, ATG18A, FLJ10055, WIPI49 ENSG00000070540 WD repeat domain, phosphoinositide interacting 1 17 68420948-68457513 Predicted intracellular proteins Evidence at protein level HPA007493, CAB037230 Enhanced Melanoma:3.11e-4 (favourable) Expressed in all Expressed in all placenta: 90.1 Cell line enhanced HHSteC: 180.5 +FRMPD1 FRMD2, KIAA0967 ENSG00000070601 FERM and PDZ domain containing 1 9 37651000-37746904 Predicted intracellular proteins Evidence at protein level HPA042934 Uncertain Mixed Tissue enhanced testis: 14.3 skin: 8.2 Cell line enhanced SCLC-21H: 3.1 +GBA2 AD035, DKFZp762K054, KIAA1605, SPG46 ENSG00000070610 Glucosylceramidase beta 2 9 35736866-35749228 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA024026 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:1.24e-11 (favourable), Pancreatic cancer:6.00e-4 (favourable), Urothelial cancer:6.60e-4 (favourable) Expressed in all Expressed in all small intestine: 64.2 Expressed in all +NDST1 HSST, NST1 ENSG00000070614 N-deacetylase and N-sulfotransferase 1 5 150485818-150558211 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060532 Approved Ovarian cancer:5.13e-4 (unfavourable), Endometrial cancer:6.99e-4 (unfavourable) Expressed in all Expressed in all spleen: 59.7 Expressed in all +ASNS ENSG00000070669 Asparagine synthetase (glutamine-hydrolyzing) 7 97852118-97872542 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004924, HPA029318, HPA064737 Approved Enhanced Cytosol Renal cancer:6.21e-7 (unfavourable), Liver cancer:9.42e-6 (unfavourable), Head and neck cancer:8.79e-5 (unfavourable), Endometrial cancer:4.24e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 74.0 Expressed in all +AP3M2 AP47B, CLA20 ENSG00000070718 Adaptor related protein complex 3 mu 2 subunit 8 42152946-42171673 Predicted intracellular proteins Evidence at protein level CAB014876, HPA045591, HPA048380 Approved Urothelial cancer:2.38e-4 (favourable), Endometrial cancer:3.46e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 46.9 Expressed in all +CNGB1 CNCG2, CNCG3L, CNGB1B, GAR1, GARP, RCNC2, RCNCb, RP45 ENSG00000070729 Cyclic nucleotide gated channel beta 1 16 57882340-57971116 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039159, HPA060355 Approved Vesicles
Cytosol Tissue enriched Tissue enhanced adrenal gland: 1.6 appendix,cerebral cortex: 1.5 Cell line enhanced SCLC-21H: 2.6;SiHa: 3.1 +ST6GALNAC2 SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM ENSG00000070731 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 17 76565379-76586956 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048849 Uncertain Pancreatic cancer:6.48e-4 (unfavourable) Expressed in all Tissue enhanced fallopian tube: 68.6;skin: 50.8 testis: 38.9 Cell line enhanced BEWO: 20.9;HaCaT: 23.9;hTCEpi: 48.8;MCF7: 20.9;SK-MEL-30: 70.3 +CHAT ENSG00000070748 Choline O-acetyltransferase 10 49609095-49665104 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB002313, HPA048547 Supported Not detected Tissue enriched 8 placenta: 7.2 duodenum: 0.8 Cell line enriched 9 NB-4: 7.2 +PABPC1 PAB1, PABP1, PABPC2, PABPL1 ENSG00000070756 Poly(A) binding protein cytoplasmic 1 8 100685816-100722809 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011536, HPA045423, HPA067156 Enhanced Supported Cytosol Renal cancer:5.70e-12 (unfavourable), Glioma:1.35e-4 (favourable), Liver cancer:5.80e-4 (unfavourable) Expressed in all Expressed in all esophagus: 1151.0 Expressed in all +TESK2 ENSG00000070759 Testis-specific kinase 2 1 45343883-45491166 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027257, HPA063869 Uncertain Enhanced Nucleoplasm Cervical cancer:2.22e-4 (favourable) Expressed in all Mixed prostate: 25.0 Mixed +CFAP20 C16orf80, fSAP23, GTL3 ENSG00000070761 Cilia and flagella associated protein 20 16 58113588-58129450 Predicted intracellular proteins Evidence at protein level HPA018195 Uncertain Supported Nucleus Expressed in all Expressed in all fallopian tube: 54.4 Expressed in all +CSNK2A2 CK2alpha', CSNK2A1 ENSG00000070770 Casein kinase 2 alpha 2 16 58157907-58197920 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA077719 Approved Nucleoplasm
Vesicles
Cytosol Head and neck cancer:1.40e-5 (unfavourable), Liver cancer:1.80e-4 (unfavourable) Expressed in all Expressed in all testis: 237.6 Expressed in all +PTPN21 PTPD1, PTPRL10 ENSG00000070778 Protein tyrosine phosphatase, non-receptor type 21 14 88465778-88554733 Enzymes, Predicted intracellular proteins Evidence at protein level CAB011468, HPA073999 Approved Approved Nucleoplasm
Golgi apparatus
Plasma membrane
Microtubule organizing center
Cytosol Renal cancer:3.16e-9 (favourable) Expressed in all Mixed skin: 34.5 Cell line enhanced RH-30: 34.1 +EIF2B3 EIF-2B, EIF2Bgamma ENSG00000070785 Eukaryotic translation initiation factor 2B subunit gamma 1 44850522-44986722 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024213, HPA024218, HPA024219 Supported Supported Vesicles
Cytosol Liver cancer:1.73e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.4 Expressed in all +CAMK2A CAMKA, CaMKIINalpha, KIAA0968 ENSG00000070808 Calcium/calmodulin dependent protein kinase II alpha 5 150219491-150290291 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB004330, HPA051783, HPA051785, HPA053973 Enhanced Supported Plasma membrane
Cell Junctions
Cytosol Tissue enriched Tissue enriched 9 cerebral cortex: 283.6 skeletal muscle: 33.3 Cell line enhanced SCLC-21H: 6.2;U-87 MG: 4.3 +TCOF1 TCS, treacle ENSG00000070814 Treacle ribosome biogenesis factor 1 5 150357639-150400308 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033199, HPA038237, HPA038238 Enhanced Enhanced Nucleoli fibrillar center Liver cancer:2.26e-8 (unfavourable), Renal cancer:2.62e-5 (unfavourable) Expressed in all Expressed in all lymph node: 22.0 Expressed in all +CDC42 CDC42Hs, G25K ENSG00000070831 Cell division cycle 42 1 22052627-22092946 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004360, HPA069590 Approved Enhanced Microtubules
Cytokinetic bridge Liver cancer:5.28e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 252.6 Expressed in all +OSBPL3 KIAA0704, ORP-3, ORP3, OSBP3 ENSG00000070882 Oxysterol binding protein like 3 7 24796539-24981634 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000691, HPA048401 Enhanced Supported Nucleoli
Cytosol Pancreatic cancer:7.88e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 33.4 Mixed +EPHA8 EEK, Hek3 ENSG00000070886 EPH receptor A8 1 22563564-22603594 Cancer-related genes, Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009660, HPA031433 Uncertain Mixed Tissue enhanced adrenal gland: 4.7;spleen: 2.6;testis: 1.9 cerebral cortex: 1.3 Cell line enriched 14 SCLC-21H: 70.4 +SLC12A3 NCCT ENSG00000070915 Solute carrier family 12 member 3 16 56865207-56915850 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA028748 Enhanced Tissue enhanced Tissue enriched 109 kidney: 109.8 lymph node: 1.0 Group enriched 11 BEWO: 7.0;HAP1: 4.1;HeLa: 5.5 +RAD18 RNF73 ENSG00000070950 RAD18, E3 ubiquitin protein ligase 3 8775402-8963773 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006716, HPA006724, HPA008752 Supported Approved Enhanced Nucleoplasm
Nuclear bodies Renal cancer:3.65e-5 (unfavourable), Liver cancer:1.12e-4 (unfavourable), Prostate cancer:3.73e-4 (unfavourable) Expressed in all Mixed duodenum: 10.2 Expressed in all +ATP2B1 PMCA1 ENSG00000070961 ATPase plasma membrane Ca2+ transporting 1 12 89588049-89709300 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB005605, HPA011166, HPA012945 Enhanced Supported Plasma membrane Liver cancer:7.74e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 143.6 Expressed in all +TRPM5 LTRPC5, MTR1 ENSG00000070985 Transient receptor potential cation channel subfamily M member 5 11 2404515-2423045 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA042115, HPA043315 Uncertain Tissue enhanced Group enriched 5 colon: 1.0;duodenum: 2.9;epididymis: 2.2;seminal vesicle: 2.5;small intestine: 2.9 testis,thyroid gland: 0.4 Not detected +NCK2 NCKbeta ENSG00000071051 NCK adaptor protein 2 2 105744897-105894274 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016116, HPA031004 Approved Expressed in all Expressed in all small intestine: 58.3 Cell line enhanced SK-MEL-30: 139.0 +MAP4K4 FLH21957, HGK, NIK ENSG00000071054 Mitogen-activated protein kinase kinase kinase kinase 4 2 101696850-101894689 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008476 Uncertain Renal cancer:3.62e-6 (unfavourable), Lung cancer:1.57e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 154.6 Mixed +MGAT4A GnT-4a, GnT-Iva ENSG00000071073 Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 2 98619106-98731126 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007608 Enhanced Approved Golgi apparatus Endometrial cancer:6.48e-8 (unfavourable), Breast cancer:4.30e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 84.1 Cell line enhanced BEWO: 122.6;TIME: 64.1 +RPL31 L31 ENSG00000071082 Ribosomal protein L31 2 101001715-101024032 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA072263 Approved Renal cancer:8.08e-6 (unfavourable) Expressed in all Expressed in all ovary: 5539.1 Expressed in all +WDR1 ENSG00000071127 WD repeat domain 1 4 10074339-10116949 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB020804, HPA036434, HPA070293 Approved Supported Plasma membrane
Cell Junctions Renal cancer:1.73e-5 (favourable) Expressed in all Expressed in all smooth muscle: 308.6 Expressed in all +SNX13 KIAA0713, RGS-PX1 ENSG00000071189 Sorting nexin 13 7 17790761-17940501 Predicted membrane proteins Evidence at protein level Renal cancer:5.98e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 32.3 Expressed in all +MS4A12 FLJ20217, Ms4a10 ENSG00000071203 Membrane spanning 4-domains A12 11 60492778-60507430 Predicted membrane proteins Evidence at protein level HPA057657 Enhanced Tissue enriched Group enriched 19 colon: 235.5;rectum: 280.6 appendix: 13.2 Cell line enhanced RH-30: 1.1 +ARHGAP10 FLJ20896, FLJ41791, GRAF2 ENSG00000071205 Rho GTPase activating protein 10 4 147732063-148072780 Predicted intracellular proteins Evidence at protein level HPA039589 Approved Nucleoplasm
Nuclear membrane
Cytosol Renal cancer:8.15e-5 (favourable), Lung cancer:2.23e-4 (unfavourable), Stomach cancer:6.26e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 44.1 Mixed +RPS6KA2 HU-2, RSK, RSK3 ENSG00000071242 Ribosomal protein S6 kinase A2 6 166409364-166906451 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB026243, HPA045061, HPA054237, CAB069428 Approved Supported Nucleoplasm Renal cancer:2.86e-5 (favourable), Ovarian cancer:8.63e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 74.4 Cell line enhanced ASC diff: 147.2;HHSteC: 133.3;hTERT-HME1: 133.1 +ING3 Eaf4, FLJ20089, MEAF4, p47ING3 ENSG00000071243 Inhibitor of growth family member 3 7 120950749-120977216 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA067388, HPA067575 Approved Supported Nucleus Expressed in all Expressed in all bone marrow: 50.3 Expressed in all +VASH1 KIAA1036 ENSG00000071246 Vasohibin 1 14 76762189-76783015 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000653 Uncertain Pancreatic cancer:6.56e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 34.4 Cell line enhanced AF22: 50.3;HUVEC TERT2: 78.5 +LMCD1 ENSG00000071282 LIM and cysteine rich domains 1 3 8501707-8574673 Predicted intracellular proteins Evidence at protein level HPA024059 Enhanced Supported Nucleus
Plasma membrane
Cell Junctions
Cytosol Renal cancer:8.66e-5 (unfavourable) Expressed in all Mixed skeletal muscle: 201.9 Cell line enhanced HSkMC: 90.7;hTEC/SVTERT24-B: 93.9 +WBSCR22 MERM1, MGC19709, MGC2022, MGC5140, PP3381, WBMT ENSG00000071462 Williams-Beuren syndrome chromosome region 22 7 73683025-73705161 Predicted intracellular proteins Evidence at protein level HPA052185 Approved Supported Nucleus
Nucleoli Renal cancer:1.46e-4 (unfavourable), Liver cancer:9.92e-4 (unfavourable) Expressed in all Expressed in all testis: 207.8 Expressed in all +SEL1L IBD2, SEL1L1 ENSG00000071537 SEL1L ERAD E3 ligase adaptor subunit 14 81471549-81533861 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA024267 Approved Expressed in all Expressed in all thyroid gland: 90.5 Expressed in all +TRIP13 16E1BP ENSG00000071539 Thyroid hormone receptor interactor 13 5 892643-919357 Predicted intracellular proteins Evidence at protein level HPA005727, HPA053093 Enhanced Approved Nucleus Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.30e-6 (unfavourable), Ovarian cancer:1.39e-4 (favourable), Endometrial cancer:3.93e-4 (unfavourable) Mixed Tissue enriched 5 testis: 53.5 fallopian tube: 9.9 Mixed +ATP6AP1 16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3 ENSG00000071553 ATPase H+ transporting accessory protein 1 X 154428632-154436516 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB015218 Uncertain Approved Plasma membrane
Microtubules
Cytosol Renal cancer:5.26e-8 (favourable), Breast cancer:2.40e-4 (unfavourable), Glioma:7.82e-4 (unfavourable), Pancreatic cancer:7.83e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 209.7 Expressed in all +TCF3 bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, VDIR ENSG00000071564 Transcription factor 3 19 1609290-1652605 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB018351, HPA049808, HPA062476 Approved Enhanced Nucleoplasm Renal cancer:1.53e-4 (unfavourable), Liver cancer:2.46e-4 (unfavourable) Expressed in all Expressed in all testis: 103.3 Expressed in all +TRIB2 GS3955, TRB2 ENSG00000071575 Tribbles pseudokinase 2 2 12716889-12742734 Enzymes, Predicted membrane proteins Evidence at protein level HPA001305 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all ovary: 117.2 Cell line enhanced AN3-CA: 170.0;K-562: 229.8;WM-115: 243.3 +DAZAP1 MGC19907 ENSG00000071626 DAZ associated protein 1 19 1407569-1435687 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004201, HPA004631 Enhanced Enhanced Nucleoplasm
Cytosol Liver cancer:5.86e-4 (unfavourable) Expressed in all Expressed in all testis: 102.8 Expressed in all +MBD3 ENSG00000071655 Methyl-CpG binding domain protein 3 19 1573596-1592801 Predicted intracellular proteins Evidence at protein level CAB013265 Supported Supported Nucleoplasm Pancreatic cancer:1.76e-5 (favourable), Liver cancer:2.99e-4 (unfavourable), Endometrial cancer:5.08e-4 (favourable) Expressed in all Expressed in all placenta: 45.8 Expressed in all +PRLH PRH ENSG00000071677 Prolactin releasing hormone 2 237566574-237567175 Predicted secreted proteins Evidence at protein level HPA014976 Supported Tissue enhanced Not detected fallopian tube,heart muscle: 0.6 Cell line enhanced A549: 2.1;MCF7: 1.3;RPMI-8226: 1.0 +HLTF HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3 ENSG00000071794 Helicase like transcription factor 3 149030127-149086554 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015284, HPA049001 Uncertain Enhanced Nucleus Liver cancer:7.27e-4 (unfavourable) Expressed in all Expressed in all testis: 83.4 Expressed in all +FAM50A 9F, DXS9928E, HXC-26, XAP5 ENSG00000071859 Family with sequence similarity 50 member A X 154444126-154450654 Predicted intracellular proteins Evidence at protein level HPA003585 Supported Enhanced Nucleoplasm Liver cancer:3.15e-5 (unfavourable), Colorectal cancer:9.52e-5 (unfavourable), Cervical cancer:2.05e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 67.0 Expressed in all +FAM3A 2-19, DXS560S, XAP-7 ENSG00000071889 Family with sequence similarity 3 member A X 154506159-154516242 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025016, HPA056991 Uncertain Approved Nucleus
Nucleoli Colorectal cancer:1.76e-4 (unfavourable) Expressed in all Expressed in all small intestine: 28.3 Expressed in all +CPSF1 ENSG00000071894 Cleavage and polyadenylation specific factor 1 8 144393229-144409349 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065167, HPA068906 Enhanced Nucleoplasm Renal cancer:6.54e-5 (unfavourable), Liver cancer:8.64e-4 (unfavourable) Expressed in all Expressed in all testis: 63.5 Expressed in all +MYO3B ENSG00000071909 Myosin IIIB 2 170178145-170655171 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045483 Approved Mixed Group enriched 5 epididymis: 11.8;kidney: 4.8;parathyroid gland: 15.3;urinary bladder: 4.2 thyroid gland: 1.6 Group enriched 11 HDLM-2: 8.9;HEL: 7.8;RT4: 7.8 +CYBRD1 CYB561A2, DCYTB, FLJ23462, FRRS3 ENSG00000071967 Cytochrome b reductase 1 2 171522247-171558133 Predicted membrane proteins Evidence at protein level HPA014757, HPA056736 Approved Approved Golgi apparatus
Cytosol Expressed in all Expressed in all thyroid gland: 381.1 Cell line enhanced ASC diff: 712.0;ASC TERT1: 313.5;BJ hTERT+: 328.5 +CDH19 CDH7 ENSG00000071991 Cadherin 19 18 66501083-66604138 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA056332 Uncertain Tissue enriched Mixed heart muscle: 8.4 Group enriched 15 SK-MEL-30: 28.3;WM-115: 63.0 +PDCD2 RP8, ZMYND7 ENSG00000071994 Programmed cell death 2 6 170575295-170584692 Predicted intracellular proteins Evidence at protein level HPA026713, HPA075534 Uncertain Approved Nucleoplasm
Cytokinetic bridge Liver cancer:1.42e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 57.9 Expressed in all +SLC6A15 FLJ10316, hv7-3, NTT73, SBAT1, V7-3 ENSG00000072041 Solute carrier family 6 member 15 12 84859488-84913615 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA008609 Uncertain Approved Nucleoli
Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 23.0 placenta: 5.5 Cell line enhanced ASC diff: 62.0;hTERT-HME1: 99.4;SCLC-21H: 104.6 +RDH11 ARSDR1, MDT1, SDR7C1 ENSG00000072042 Retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 14 67676801-67695814 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB046011 Enhanced Renal cancer:1.30e-7 (favourable), Head and neck cancer:2.89e-5 (unfavourable), Endometrial cancer:2.62e-4 (favourable) Tissue enriched Tissue enriched 7 prostate: 941.3 parathyroid gland: 125.7 Expressed in all +PRKACA PKACa ENSG00000072062 Protein kinase cAMP-activated catalytic subunit alpha 19 14091688-14118084 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010361, HPA071185 Approved Approved Cytosol Cervical cancer:6.28e-6 (favourable), Endometrial cancer:6.26e-5 (unfavourable), Pancreatic cancer:6.47e-4 (favourable) Expressed in all Expressed in all heart muscle: 200.4 Expressed in all +ADGRL1 CIRL1, KIAA0821, LEC2, LPHN1 ENSG00000072071 Adhesion G protein-coupled receptor L1 19 14147743-14206187 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA037974 Uncertain Pancreatic cancer:1.14e-4 (favourable), Renal cancer:4.45e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 60.1 parathyroid gland: 24.2 Cell line enhanced AN3-CA: 66.4;SCLC-21H: 64.6 +SPP2 SPP24 ENSG00000072080 Secreted phosphoprotein 2 2 234050679-234077134 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Liver cancer:2.33e-6 (favourable) Tissue enriched Tissue enriched 2145 liver: 265.4 kidney,testis: 0.1 Not detected +ACTN1 ENSG00000072110 Actinin alpha 1 14 68874143-68979440 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004303, HPA006035 Approved Approved Plasma membrane
Focal adhesion sites Renal cancer:9.08e-10 (unfavourable), Lung cancer:7.63e-5 (unfavourable), Head and neck cancer:2.49e-4 (unfavourable), Urothelial cancer:8.00e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 754.0 Mixed +ZFYVE26 KIAA0321, SPG15 ENSG00000072121 Zinc finger FYVE-type containing 26 14 67727374-67816590 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055500 Approved Renal cancer:1.54e-6 (favourable), Liver cancer:2.84e-6 (unfavourable) Expressed in all Mixed parathyroid gland: 14.7 Expressed in all +RPS6KA6 RSK4 ENSG00000072133 Ribosomal protein S6 kinase A6 X 84058346-84187907 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002852, HPA003904 Uncertain Supported Nucleus
Nucleoli
Mitochondria Mixed Tissue enhanced parathyroid gland: 18.9;thyroid gland: 21.9 kidney: 8.9 Cell line enhanced PC-3: 13.7;RH-30: 17.3;SH-SY5Y: 15.2 +EPN2 EHB21, KIAA1065 ENSG00000072134 Epsin 2 17 19215615-19336715 Predicted intracellular proteins Evidence at protein level HPA049809, HPA053360 Approved Supported Vesicles Urothelial cancer:8.15e-5 (unfavourable), Renal cancer:9.13e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 95.0 Mixed +PTPN18 BDP1 ENSG00000072135 Protein tyrosine phosphatase, non-receptor type 18 2 130356007-130375409 Enzymes, Predicted intracellular proteins Evidence at protein level CAB012174, HPA053367 Uncertain Approved Intermediate filaments Expressed in all Expressed in all lymph node: 47.5 Expressed in all +LIMS2 PINCH-2, PINCH2 ENSG00000072163 LIM zinc finger domain containing 2 2 127638381-127681786 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA058340 Enhanced Supported Focal adhesion sites Liver cancer:6.53e-7 (favourable) Expressed in all Mixed seminal vesicle: 137.8 Cell line enhanced HHSteC: 27.3;MOLT-4: 32.1;TIME: 66.1 +ASIC4 ACCN4, BNAC4 ENSG00000072182 Acid sensing ion channel subunit family member 4 2 219514170-219538772 Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 8 cerebral cortex: 10.6 adrenal gland: 1.3 Group enriched 43 HEL: 17.6;HMC-1: 5.0;K-562: 10.2;SH-SY5Y: 5.4 +SPEG APEG1, BPEG, KIAA1297, MGC12676, SPEGalpha, SPEGbeta ENSG00000072195 SPEG complex locus 2 219434846-219498287 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018904 Enhanced Approved Vesicles Mixed Mixed skeletal muscle: 43.2 Cell line enhanced U-2 OS: 22.8;U-87 MG: 23.6 +LNX1 LNX, MPDZ, PDZRN2 ENSG00000072201 Ligand of numb-protein X 1 4 53459301-53701405 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002235, HPA071091 Approved Supported Cell Junctions
Cytosol Renal cancer:3.08e-7 (favourable) Expressed in all Mixed placenta: 39.4 Mixed +ALDH3A2 ALDH10, FALDH, SLS ENSG00000072210 Aldehyde dehydrogenase 3 family member A2 17 19648136-19677598 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014769, CAB020692 Approved Renal cancer:3.85e-8 (favourable) Expressed in all Expressed in all adrenal gland: 179.0 Cell line enhanced A549: 115.6 +TFRC CD71, p90, TFR1 ENSG00000072274 Transferrin receptor 3 196027183-196082189 Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000153, HPA028598 Enhanced Supported Endosomes
Lysosomes Liver cancer:1.15e-4 (unfavourable), Thyroid cancer:2.96e-4 (unfavourable), Cervical cancer:3.67e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 157.4 Expressed in all +SREBF1 bHLHd1, SREBP-1c, SREBP1, SREBP1a ENSG00000072310 Sterol regulatory element binding transcription factor 1 17 17810399-17837002 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level CAB005406, HPA043343, HPA043878 Uncertain Supported Golgi apparatus
Cytosol Endometrial cancer:2.66e-4 (favourable), Pancreatic cancer:9.05e-4 (favourable) Expressed in all Expressed in all adrenal gland: 92.4 Expressed in all +TRPC5 PPP1R159 ENSG00000072315 Transient receptor potential cation channel subfamily C member 5 X 111774315-112082776 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Group enriched Tissue enhanced cerebral cortex: 1.9 liver: 0.4 Cell line enriched 5 NTERA-2: 1.7 +AFF4 AF5Q31, MCEF ENSG00000072364 AF4/FMR2 family member 4 5 132875379-132963634 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023690, HPA029634 Approved Supported Nucleus
Nucleoli fibrillar center Thyroid cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 74.2 Expressed in all +UBE2D1 E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A ENSG00000072401 Ubiquitin conjugating enzyme E2 D1 10 58334975-58370753 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003920 Approved Approved Plasma membrane
Cytosol Renal cancer:8.04e-6 (unfavourable), Liver cancer:5.58e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 47.8 Mixed +MPP5 FLJ12615, PALS1 ENSG00000072415 Membrane palmitoylated protein 5 14 67241109-67335819 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000993, HPA063890 Enhanced Uncertain Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.71e-12 (favourable), Liver cancer:5.62e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 43.9 Expressed in all +RHOBTB1 KIAA0740 ENSG00000072422 Rho related BTB domain containing 1 10 60869438-61001440 Predicted intracellular proteins Evidence at protein level HPA040205, HPA040226 Approved Approved Nucleoplasm
Cytosol Expressed in all Mixed placenta: 52.5 Cell line enhanced Hep G2: 45.7 +SMC1A DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb ENSG00000072501 Structural maintenance of chromosomes 1A X 53374149-53422728 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005499, CAB025404 Supported Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 52.8 Expressed in all +HSD17B10 17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1 ENSG00000072506 Hydroxysteroid 17-beta dehydrogenase 10 X 53431258-53434373 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001432 Approved Cervical cancer:2.80e-4 (favourable) Expressed in all Expressed in all liver: 126.6 Expressed in all +MARK2 EMK1, PAR-1, PAR-1B, Par1b ENSG00000072518 Microtubule affinity regulating kinase 2 11 63838928-63911019 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038790, HPA074905 Approved Supported Nucleoplasm
Plasma membrane Liver cancer:1.30e-4 (unfavourable), Endometrial cancer:3.21e-4 (unfavourable) Expressed in all Expressed in all skin: 46.1 Expressed in all +HMMR CD168, RHAMM ENSG00000072571 Hyaluronan mediated motility receptor 5 163460203-163491945 CD markers, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB002433, HPA040025, HPA043926, HPA061524 Enhanced Enhanced Microtubules
Centrosome
Cytosol Liver cancer:1.93e-7 (unfavourable), Pancreatic cancer:3.71e-5 (unfavourable), Lung cancer:1.09e-4 (unfavourable), Head and neck cancer:5.52e-4 (unfavourable) Mixed Tissue enhanced testis: 49.7 lymph node: 21.7 Expressed in all +CHFR FLJ10796, RNF196 ENSG00000072609 Checkpoint with forkhead and ring finger domains 12 132822187-132956304 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045768, HPA073826 Approved Uncertain Nuclear bodies
Microtubules Renal cancer:4.21e-9 (unfavourable) Expressed in all Expressed in all testis: 22.8 Mixed +TRHDE PAP-II, PGPEP2, TRH-DE ENSG00000072657 Thyrotropin releasing hormone degrading enzyme 12 72087266-72670757 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:1.53e-7 (favourable) Tissue enhanced Mixed cerebral cortex: 7.9 Cell line enhanced BJ: 25.6;BJ hTERT+: 23.6;EFO-21: 14.6 +P4HA2 C-P4Halpha(II) ENSG00000072682 Prolyl 4-hydroxylase subunit alpha 2 5 132191838-132295315 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA016997, HPA027824, CAB062557 Enhanced Enhanced Endoplasmic reticulum
Vesicles Renal cancer:2.77e-7 (unfavourable), Cervical cancer:1.24e-5 (unfavourable), Urothelial cancer:3.12e-4 (unfavourable) Expressed in all Expressed in all epididymis: 95.3 Mixed +FCGR2B CD32, CD32B, FCG2, FCGR2 ENSG00000072694 Fc fragment of IgG receptor IIb 1 161663147-161678654 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB007796, HPA014730 Enhanced Renal cancer:8.82e-4 (unfavourable) Mixed Tissue enriched 16 placenta: 576.7 adipose tissue: 36.6 Cell line enhanced Daudi: 18.5;HMC-1: 27.5;RPMI-8226: 8.1 +NFATC3 NFAT4, NFATX ENSG00000072736 Nuclear factor of activated T-cells 3 16 68084751-68229259 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050665 Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 50.0 Expressed in all +TRNT1 CCA1, CGI-47, MtCCA ENSG00000072756 TRNA nucleotidyl transferase 1 3 3126916-3150879 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036938 Uncertain Enhanced Mitochondria Expressed in all Expressed in all prostate: 24.5 Expressed in all +ACADVL ACAD6, LCACD, VLCAD ENSG00000072778 Acyl-CoA dehydrogenase, very long chain 17 7217125-7225273 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019006, HPA020595 Enhanced Supported Nucleus
Nucleoli
Mitochondria Pancreatic cancer:6.87e-4 (favourable) Expressed in all Expressed in all adrenal gland: 453.7 Expressed in all +STK10 LOK, PRO2729 ENSG00000072786 Serine/threonine kinase 10 5 172042073-172188386 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015083, CAB020840 Enhanced Renal cancer:1.63e-4 (unfavourable), Colorectal cancer:2.76e-4 (favourable) Expressed in all Expressed in all spleen: 61.0 Expressed in all +FBXW11 BTRC2, BTRCP2, Fbw11, Fbw1b, FBXW1B, Hos, KIAA0696 ENSG00000072803 F-box and WD repeat domain containing 11 5 171861549-172006873 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062578, HPA072204 Approved Approved Nucleoli
Vesicles Expressed in all Expressed in all parathyroid gland: 72.6 Expressed in all +ACAP1 CENTB1, KIAA0050 ENSG00000072818 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 17 7336529-7351478 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA075570 Approved Approved Golgi apparatus Renal cancer:1.65e-10 (unfavourable), Endometrial cancer:2.97e-5 (favourable), Head and neck cancer:4.17e-5 (favourable), Cervical cancer:3.66e-4 (favourable) Expressed in all Tissue enhanced lymph node: 94.2 spleen: 69.8 Cell line enhanced HDLM-2: 59.1;Karpas-707: 44.7;NB-4: 49.0 +CRMP1 DPYSL1, DRP-1 ENSG00000072832 Collapsin response mediator protein 1 4 5748084-5893058 Predicted intracellular proteins Evidence at protein level HPA035640, CAB037313 Approved Supported Centrosome
Cytosol Pancreatic cancer:4.54e-4 (favourable) Expressed in all Tissue enriched 5 cerebral cortex: 133.7 endometrium: 24.5 Cell line enhanced HAP1: 120.7;REH: 208.7;RH-30: 125.4;SCLC-21H: 196.8;SH-SY5Y: 112.2 +EVC DWF-1 ENSG00000072840 EvC ciliary complex subunit 1 4 5711197-5814305 Disease related genes, Predicted membrane proteins Evidence at protein level HPA008703, HPA016046 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:5.60e-9 (favourable), Urothelial cancer:9.47e-5 (unfavourable) Expressed in all Mixed ovary: 41.5 Mixed +DERL2 CGI-101, derlin-2, F-LAN-1, F-LANa, FLANa ENSG00000072849 Derlin 2 17 5471251-5486811 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB037287, HPA048957, HPA056551 Enhanced Supported Endoplasmic reticulum Renal cancer:6.49e-4 (unfavourable), Endometrial cancer:7.26e-4 (favourable) Expressed in all Expressed in all thyroid gland: 41.4 Expressed in all +SIDT1 FLJ20174, SID-1 ENSG00000072858 SID1 transmembrane family member 1 3 113532296-113629578 Predicted membrane proteins, Transporters Evidence at protein level HPA035862 Enhanced Urothelial cancer:4.09e-5 (favourable), Cervical cancer:3.78e-4 (favourable) Mixed Mixed cerebral cortex: 10.6 Cell line enhanced MCF7: 11.1;PC-3: 18.4;RT4: 11.2;T-47d: 12.3 +NDE1 FLJ20101, NDE, nudE ENSG00000072864 NudE neurodevelopment protein 1 16 15643267-15726353 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024075 Approved Renal cancer:8.19e-4 (unfavourable), Liver cancer:9.92e-4 (unfavourable) Expressed in all Mixed lymph node: 14.8 Expressed in all +MRVI1 IRAG, JAW1L ENSG00000072952 Murine retrovirus integration site 1 homolog 11 10573091-10693988 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008704 Uncertain Approved Nuclear bodies
Cytosol Endometrial cancer:5.78e-4 (favourable), Renal cancer:9.70e-4 (unfavourable) Mixed Mixed smooth muscle: 99.6 Cell line enhanced ASC diff: 14.2;BJ: 12.9;BJ hTERT+: 14.3 +TMEM38A MGC3169, TRIC-A ENSG00000072954 Transmembrane protein 38A 19 16661127-16690029 Predicted membrane proteins Evidence at protein level HPA048100, HPA050463 Enhanced Approved Nucleus Renal cancer:2.99e-10 (favourable), Lung cancer:2.78e-5 (favourable), Ovarian cancer:7.96e-4 (unfavourable) Expressed in all Tissue enriched 9 skeletal muscle: 199.7 cerebral cortex: 23.1 Cell line enhanced U-698: 18.5 +AP1M1 AP47, CLAPM2 ENSG00000072958 Adaptor related protein complex 1 mu 1 subunit 19 16197578-16245907 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045256 Uncertain Renal cancer:1.75e-4 (unfavourable) Expressed in all Expressed in all testis: 96.5 Expressed in all +PVR CD155, HVED, Necl-5, NECL5, PVS, Tage4 ENSG00000073008 Poliovirus receptor 19 44643798-44663583 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012568 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Cervical cancer:1.29e-4 (unfavourable), Urothelial cancer:2.75e-4 (unfavourable), Lung cancer:9.30e-4 (unfavourable) Expressed in all Expressed in all placenta: 17.0 Cell line enhanced TIME: 147.4 +XRCC1 RCC ENSG00000073050 X-ray repair cross complementing 1 19 43543040-43580473 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB005427, HPA006717 Supported Enhanced Nucleoplasm Liver cancer:7.33e-5 (unfavourable) Expressed in all Expressed in all ovary: 34.6 Expressed in all +SCARB1 CD36L1, CLA-1, CLA1, SR-BI, SRB1 ENSG00000073060 Scavenger receptor class B member 1 12 124776856-124882668 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA066285, CAB070124, HPA072449 Enhanced Approved Vesicles Renal cancer:1.49e-5 (unfavourable), Liver cancer:1.83e-5 (unfavourable), Lung cancer:4.02e-4 (unfavourable) Expressed in all Group enriched 7 adrenal gland: 758.4;placenta: 287.5 liver: 72.3 Mixed +CYP2W1 FLJ20359, MGC34287 ENSG00000073067 Cytochrome P450 family 2 subfamily W member 1 7 983199-989640 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012753 Uncertain Urothelial cancer:5.85e-4 (unfavourable) Group enriched Tissue enhanced adrenal gland: 5.5;duodenum: 6.2;skin: 9.7 placenta: 1.4 Group enriched 7 CACO-2: 11.2;Hep G2: 33.8 +MCM2 BM28, CCNL1, cdc19, CDCL1, D3S3194, KIAA0030 ENSG00000073111 Minichromosome maintenance complex component 2 3 127598223-127622436 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB000303, HPA031495, HPA031496 Enhanced Supported Nucleoplasm Liver cancer:1.51e-7 (unfavourable), Cervical cancer:4.66e-4 (favourable) Expressed in all Mixed bone marrow: 38.5 Expressed in all +MOV10L1 CHAMP, DJ402G11.8, DKFZp434B0717 ENSG00000073146 Mov10 RISC complex RNA helicase like 1 22 50089879-50161690 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA019034 Approved Mixed Tissue enriched 9 testis: 39.9 endometrium: 4.2 Group enriched 6 HHSteC: 2.1;HUVEC TERT2: 10.4;TIME: 4.7 +PANX2 hPANX2, PX2 ENSG00000073150 Pannexin 2 22 50170731-50180294 Predicted membrane proteins, Transporters Evidence at protein level HPA004624, HPA039117 Enhanced Approved Plasma membrane Mixed Tissue enhanced cerebral cortex: 8.7 seminal vesicle: 2.1 Cell line enhanced HDLM-2: 15.5;Hep G2: 13.2;SCLC-21H: 11.5 +SELENOO SELO ENSG00000073169 Selenoprotein O 22 50200979-50217616 Predicted secreted proteins Evidence at protein level Urothelial cancer:8.32e-4 (favourable) Expressed in all Expressed in all skin: 9.2 Expressed in all +TP63 EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L ENSG00000073282 Tumor protein p63 3 189631416-189897279 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000083, HPA006288, HPA007010 Enhanced Enhanced Nucleoplasm
Golgi apparatus
Cytosol Breast cancer:1.07e-4 (favourable) Group enriched Tissue enhanced esophagus: 60.9;skin: 164.1 urinary bladder: 28.8 Group enriched 5 HaCaT: 77.1;HBEC3-KT: 119.9;hTCEpi: 89.8;hTERT-HME1: 90.5;RT4: 147.6 +ALPK1 FLJ22670, KIAA1527, Lak ENSG00000073331 Alpha kinase 1 4 112285509-112442620 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA027435, HPA027443 Approved Approved Centrosome Renal cancer:5.82e-7 (unfavourable), Urothelial cancer:1.17e-4 (favourable) Expressed in all Mixed parathyroid gland: 9.2 Mixed +LLGL2 HGL, Hugl-2 ENSG00000073350 LLGL2, scribble cell polarity complex component 17 75525080-75575208 Predicted intracellular proteins Evidence at protein level HPA022913 Uncertain Supported Vesicles
Cytosol Renal cancer:6.14e-9 (favourable), Pancreatic cancer:6.00e-5 (favourable), Head and neck cancer:9.25e-4 (favourable) Expressed in all Mixed stomach: 62.8 Cell line enhanced CAPAN-2: 118.0;MCF7: 101.3;SK-BR-3: 95.4;T-47d: 90.7 +PDE8A HsT19550 ENSG00000073417 Phosphodiesterase 8A 15 84980440-85139145 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007722 Approved Approved Golgi apparatus Expressed in all Expressed in all parathyroid gland: 30.2 Expressed in all +CLCN4 ClC-4, CLC4 ENSG00000073464 Chloride voltage-gated channel 4 X 10156945-10237660 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA031313, HPA063637 Enhanced Approved Vesicles Endometrial cancer:2.13e-5 (unfavourable), Pancreatic cancer:9.55e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 49.1;epididymis: 28.1 skeletal muscle: 14.6 Cell line enhanced HEL: 21.9;SCLC-21H: 28.6 +NLE1 FLJ10458 ENSG00000073536 Notchless homolog 1 17 35128753-35142315 Predicted intracellular proteins Evidence at protein level HPA018807 Approved Supported Nucleus
Nucleoli Liver cancer:8.64e-8 (unfavourable), Urothelial cancer:6.39e-4 (unfavourable) Expressed in all Expressed in all ovary: 15.9 Expressed in all +SDHA FP, SDH2, SDHF ENSG00000073578 Succinate dehydrogenase complex flavoprotein subunit A 5 218241-256700 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB034929, HPA041981, HPA064582 Enhanced Enhanced Mitochondria Renal cancer:9.53e-8 (favourable), Breast cancer:6.00e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 248.9 Expressed in all +SMARCE1 BAF57 ENSG00000073584 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 17 40624962-40648508 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003916, CAB037318 Enhanced Supported Nucleoplasm Expressed in all Expressed in all endometrium: 74.3 Expressed in all +FNDC8 DKFZp434H2215 ENSG00000073598 Fibronectin type III domain containing 8 17 35121579-35130732 Predicted intracellular proteins Evidence at protein level HPA026521 Supported Not detected Tissue enriched 461 testis: 108.6 ovary: 0.2 Cell line enhanced HEK 293: 1.2 +GSDMB GSDML, PRO2521 ENSG00000073605 Gasdermin B 17 39904595-39919854 Predicted intracellular proteins, Transporters Evidence at protein level CAB013681, HPA023925, HPA052407 Enhanced Renal cancer:5.13e-11 (unfavourable), Urothelial cancer:5.91e-9 (favourable), Cervical cancer:3.41e-5 (favourable) Expressed in all Tissue enhanced duodenum: 67.0;small intestine: 85.1 rectum: 62.6 Cell line enriched 7 SK-BR-3: 342.4 +KDM5A JARID1A, RBBP2 ENSG00000073614 Lysine demethylase 5A 12 280129-389454 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006201 Supported Nuclear bodies
Cytosol Expressed in all Expressed in all testis: 39.0 Expressed in all +ADAM11 MDC ENSG00000073670 ADAM metallopeptidase domain 11 17 44759031-44781846 Predicted membrane proteins, Transporters Evidence at protein level HPA074550 Enhanced Mixed Tissue enhanced cerebral cortex: 19.8 heart muscle: 4.0 Cell line enhanced HEK 293: 18.5 +PPP2R3A PPP2R3 ENSG00000073711 Protein phosphatase 2 regulatory subunit B''alpha 3 135965673-136147891 Predicted intracellular proteins Evidence at protein level HPA035829, HPA035830, HPA065338 Uncertain Approved Golgi apparatus Pancreatic cancer:1.14e-5 (unfavourable), Renal cancer:1.15e-5 (favourable), Urothelial cancer:3.91e-4 (unfavourable), Endometrial cancer:4.38e-4 (unfavourable) Mixed Tissue enhanced skeletal muscle: 63.3 heart muscle: 34.3 Mixed +FERMT2 KIND2, mig-2, PLEKHC1, UNC112B ENSG00000073712 Fermitin family member 2 14 52857268-52952435 Predicted intracellular proteins Evidence at protein level HPA040505 Uncertain Supported Nucleoplasm
Focal adhesion sites Expressed in all Mixed smooth muscle: 222.9 Mixed +ABCB11 ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP ENSG00000073734 ATP binding cassette subfamily B member 11 2 168922938-169031322 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA019035 Enhanced Uncertain Nucleoplasm
Plasma membrane
Cytosol Tissue enriched Tissue enriched 13 liver: 19.1 testis: 1.4 Not detected +DHRS9 3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4 ENSG00000073737 Dehydrogenase/reductase 9 2 169064789-169096167 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA036491, HPA036667 Approved Pancreatic cancer:2.73e-4 (unfavourable) Tissue enhanced Tissue enhanced colon: 66.5;rectum: 48.1 esophagus: 30.1 Cell line enhanced NB-4: 21.6;THP-1: 66.4;TIME: 35.4;U-2197: 29.3 +CD5L API6, Spalpha ENSG00000073754 CD5 molecule like 1 157830914-157898256 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA065686, HPA068384 Enhanced Liver cancer:8.88e-5 (favourable) Tissue enriched Tissue enriched 14 spleen: 787.1 liver: 54.4 Not detected +PTGS2 COX2 ENSG00000073756 Prostaglandin-endoperoxide synthase 2 1 186671791-186680427 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level CAB000113, HPA001335 Approved Supported Endoplasmic reticulum Renal cancer:9.79e-4 (unfavourable) Mixed Tissue enhanced seminal vesicle: 180.6 cervix, uterine: 99.3 Group enriched 7 BJ: 78.6;BJ hTERT+: 327.8 +IGF2BP2 IMP-2 ENSG00000073792 Insulin like growth factor 2 mRNA binding protein 2 3 185643739-185825056 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017126, HPA035145 Enhanced Enhanced Cytosol Head and neck cancer:5.12e-5 (unfavourable), Pancreatic cancer:7.37e-5 (unfavourable), Endometrial cancer:1.22e-4 (unfavourable) Mixed Mixed placenta: 21.1 Mixed +MAP3K13 LZK, MEKK13 ENSG00000073803 Mitogen-activated protein kinase kinase kinase 13 3 185282941-185489097 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA016497, HPA036691, HPA036692 Uncertain Approved Nucleoplasm
Microtubule organizing center
Cytosol Endometrial cancer:1.28e-5 (unfavourable), Pancreatic cancer:7.27e-5 (unfavourable), Ovarian cancer:1.11e-4 (favourable) Expressed in all Expressed in all epididymis: 69.3 Mixed +ST6GAL1 SIAT1 ENSG00000073849 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 3 186930485-187078553 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB015018, CAB016122 Supported Expressed in all Expressed in all liver: 270.5 Cell line enhanced U-266/70: 590.1;U-266/84: 742.8;U-698: 257.3 +TBX21 T-bet, TBLYM ENSG00000073861 T-box 21 17 47733244-47746119 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009524, CAB030043 Enhanced Mixed Tissue enhanced lymph node: 8.5;spleen: 11.1 bone marrow: 6.4 Cell line enriched 152 HDLM-2: 15.1 +FRY 13CDNA73, bA37E23.1, C13orf14, CG003 ENSG00000073910 FRY microtubule binding protein 13 32031300-32299122 Predicted intracellular proteins Evidence at protein level HPA041635 Approved Renal cancer:9.60e-4 (favourable) Mixed Expressed in all heart muscle: 33.5 Cell line enhanced HUVEC TERT2: 22.7;RT4: 25.4 +PICALM CALM, CLTH ENSG00000073921 Phosphatidylinositol binding clathrin assembly protein 11 85957684-86069882 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019053, HPA019061 Enhanced Supported Vesicles Renal cancer:2.02e-6 (favourable), Pancreatic cancer:6.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 297.2 Expressed in all +NSF SKD2 ENSG00000073969 N-ethylmaleimide sensitive factor, vesicle fusing ATPase 17 46590669-46757464 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA003154, CAB009324, CAB013645, HPA071089 Enhanced Supported Cytosol Expressed in all Tissue enriched 5 cerebral cortex: 134.3 parathyroid gland: 25.6 Mixed +GLI2 HPE9, THP1, THP2 ENSG00000074047 GLI family zinc finger 2 2 120735623-120992653 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB008558, HPA074275 Approved Supported Nucleus
Nucleoli Mixed Tissue enhanced ovary: 11.6 gallbladder: 6.0 Cell line enhanced AF22: 30.8;U-2 OS: 33.2;WM-115: 27.2 +CLASP1 KIAA0622, MAST1 ENSG00000074054 Cytoplasmic linker associated protein 1 2 121337776-121649587 Predicted intracellular proteins Evidence at protein level HPA065219 Uncertain Renal cancer:6.50e-4 (unfavourable) Expressed in all Expressed in all testis: 34.4 Expressed in all +MRPS34 MGC2616, MRP-S12 ENSG00000074071 Mitochondrial ribosomal protein S34 16 1771890-1773155 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA042112 Supported Supported Mitochondria Expressed in all Expressed in all skeletal muscle: 22.2 Expressed in all +NOTCH3 CADASIL, CASIL ENSG00000074181 Notch 3 19 15159038-15200981 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB005393, HPA044392 Approved Supported Nucleoplasm
Actin filaments
Cytosol Renal cancer:2.53e-7 (unfavourable), Endometrial cancer:5.92e-4 (unfavourable) Expressed in all Mixed skin: 93.6 Cell line enhanced AF22: 65.5;MCF7: 51.9 +CLNS1A CLCI, ICln ENSG00000074201 Chloride nucleotide-sensitive channel 1A 11 77514936-77637805 Predicted intracellular proteins, Transporters Evidence at protein level CAB017840, HPA031707, HPA031708, HPA032045 Approved Supported Nucleus
Microtubules
Cytosol Renal cancer:5.07e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 132.0 Expressed in all +PPP2R2C IMYPNO, MGC33570, PR52, PR55G ENSG00000074211 Protein phosphatase 2 regulatory subunit Bgamma 4 6320578-6563600 Predicted intracellular proteins Evidence at protein level HPA042122, HPA042770 Approved Lung cancer:4.94e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 164.4 endometrium: 53.2 Cell line enhanced A-431: 30.5;A549: 45.5;MCF7: 32.3;PC-3: 43.7;SCLC-21H: 53.0 +TEAD2 ETF, TEF-4, TEF4 ENSG00000074219 TEA domain transcription factor 2 19 49340595-49362457 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA066292, HPA069963 Enhanced Nucleoplasm Liver cancer:8.66e-4 (unfavourable) Expressed in all Mixed endometrium: 58.9 Cell line enhanced AF22: 134.1;AN3-CA: 137.1 +EED HEED, WAIT-1 ENSG00000074266 Embryonic ectoderm development 11 86244544-86278813 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB012211, HPA060089, HPA061140 Supported Supported Nucleoplasm Renal cancer:1.36e-7 (unfavourable), Liver cancer:1.80e-5 (unfavourable), Urothelial cancer:2.27e-5 (favourable) Expressed in all Expressed in all lymph node: 30.3 Expressed in all +CDHR2 FLJ20124, FLJ20383, PC-LKC, PCDH24, PCLKC ENSG00000074276 Cadherin related family member 2 5 176542511-176595974 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA012569, HPA017053 Enhanced Renal cancer:9.29e-4 (favourable) Group enriched Group enriched 12 duodenum: 276.5;small intestine: 260.3 colon: 22.6 Cell line enriched 12 Hep G2: 15.0 +SNCB ENSG00000074317 Synuclein beta 5 176620084-176630556 Predicted intracellular proteins Evidence at protein level CAB002681, HPA035876 Enhanced Supported Tissue enriched Tissue enriched 71 cerebral cortex: 329.2 adrenal gland: 4.6 Cell line enriched 15 SCLC-21H: 68.9 +TSG101 TSG10, VPS23 ENSG00000074319 Tumor susceptibility 101 11 18468336-18527232 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004283, HPA006161 Approved Supported Nucleoli
Plasma membrane
Cytosol Liver cancer:3.74e-6 (unfavourable), Renal cancer:5.52e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 81.8 Expressed in all +NCBP3 C17orf85, ELG, HSA277841 ENSG00000074356 Nuclear cap binding subunit 3 17 3802165-3846251 Predicted intracellular proteins Evidence at protein level HPA008959, HPA013195 Supported Approved Nuclear speckles Melanoma:4.68e-4 (unfavourable), Prostate cancer:4.90e-4 (unfavourable) Expressed in all Expressed in all testis: 16.3 Expressed in all +ATP2A3 SERCA3 ENSG00000074370 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 17 3923870-3964464 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA007180, CAB010882 Approved Cervical cancer:4.69e-5 (favourable), Head and neck cancer:2.51e-4 (favourable) Expressed in all Expressed in all lymph node: 118.4 Cell line enhanced Daudi: 133.8;HMC-1: 234.0;MOLT-4: 202.8;SK-BR-3: 146.3 +CA12 HsT18816 ENSG00000074410 Carbonic anhydrase 12 15 63321378-63382161 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA008773, CAB025181, CAB062549, CAB068179, HPA073203 Enhanced Approved Nucleus
Vesicles Pancreatic cancer:3.80e-6 (unfavourable) Expressed in all Tissue enhanced kidney: 308.4;skin: 168.3 rectum: 102.9 Cell line enhanced A549: 191.8;RT4: 180.0;T-47d: 269.1;U-138 MG: 295.7;U-87 MG: 352.6 +MGLL HU-K5, MGL ENSG00000074416 Monoglyceride lipase 3 127689062-127823250 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011348, HPA011993, HPA011994 Enhanced Supported Nucleoplasm Pancreatic cancer:6.41e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 188.3 Cell line enhanced BJ hTERT+: 193.8 +NTN4 ENSG00000074527 Netrin 4 12 95657807-95791152 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049832 Approved Renal cancer:8.12e-9 (favourable), Urothelial cancer:6.67e-5 (favourable), Pancreatic cancer:9.50e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 246.4 kidney: 118.6 Cell line enhanced BJ hTERT+: 407.7;TIME: 235.1 +BCS1L BCS, BJS, h-BCS, Hs.6719 ENSG00000074582 BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone 2 218658764-218663443 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA037700, HPA037701 Enhanced Urothelial cancer:3.31e-4 (favourable) Expressed in all Expressed in all fallopian tube: 31.2 Expressed in all +NUAK1 ARK5, KIAA0537, NuaK1 ENSG00000074590 NUAK family kinase 1 12 106063340-106140033 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA057143 Supported Nucleus
Nucleoli fibrillar center
Microtubules Stomach cancer:4.27e-4 (unfavourable), Endometrial cancer:9.83e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 47.0;parathyroid gland: 42.5 skin: 21.0 Cell line enhanced AF22: 50.0;EFO-21: 47.3;RH-30: 70.1 +DPP8 DP8, DPRP1, FLJ14920, FLJ20283, MGC26191, MSTP141 ENSG00000074603 Dipeptidyl peptidase 8 15 65442463-65517704 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008706 Approved Supported Cytosol Expressed in all Expressed in all testis: 48.0 Expressed in all +SLC24A1 CSNB1D, HsT17412, KIAA0702, NCKX, NCKX1, RODX ENSG00000074621 Solute carrier family 24 member 1 15 65611366-65660995 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039370 Supported Approved Microtubules Renal cancer:2.33e-6 (favourable) Expressed in all Mixed fallopian tube: 8.5 Mixed +ZNF532 FLJ10697 ENSG00000074657 Zinc finger protein 532 18 58862600-58986480 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015322 Approved Approved Nucleoplasm
Golgi apparatus Endometrial cancer:6.46e-5 (unfavourable), Urothelial cancer:5.76e-4 (unfavourable) Expressed in all Mixed endometrium: 104.4 Cell line enhanced AF22: 113.9 +SCARF1 KIAA0149, SREC ENSG00000074660 Scavenger receptor class F member 1 17 1633858-1645747 Predicted secreted proteins Evidence at protein level HPA072936 Enhanced Expressed in all Tissue enhanced spleen: 16.6 lung: 8.0 Cell line enhanced HEL: 5.0;HUVEC TERT2: 15.4;REH: 8.9;TIME: 19.1 +LMAN1 ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60 ENSG00000074695 Lectin, mannose binding 1 18 59327823-59359962 Disease related genes, Predicted membrane proteins Evidence at protein level HPA002320, CAB037163 Supported Uncertain Cytosol Expressed in all Expressed in all thyroid gland: 125.2 Expressed in all +HACD3 B-ind1, HSPC121, PTPLAD1 ENSG00000074696 3-hydroxyacyl-CoA dehydratase 3 15 65530418-65578352 Enzymes, Predicted membrane proteins Evidence at protein level HPA014837, HPA060347 Enhanced Enhanced Nuclear membrane
Endoplasmic reticulum
Mitochondria
Cytosol Renal cancer:3.09e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 138.9 Expressed in all +IPCEF1 KIAA0403, PIP3-E ENSG00000074706 Interaction protein for cytohesin exchange factors 1 6 154154496-154356792 Predicted intracellular proteins Evidence at protein level HPA028708, HPA028710 Approved Approved Nucleoli
Nuclear speckles
Plasma membrane
Cytoplasmic bodies Mixed Tissue enhanced thyroid gland: 66.3 cerebral cortex: 24.9 Cell line enhanced HMC-1: 17.9;THP-1: 7.2;U-937: 8.8 +ZZEF1 FLJ10821, KIAA0399, ZZZ4 ENSG00000074755 Zinc finger ZZ-type and EF-hand domain containing 1 17 4004445-4143020 Predicted membrane proteins Evidence at protein level HPA031778, HPA031790 Uncertain Approved Nucleoplasm
Mitochondria Head and neck cancer:1.02e-4 (favourable), Pancreatic cancer:6.08e-4 (favourable) Expressed in all Expressed in all small intestine: 25.8 Expressed in all +NOX3 GP91-3 ENSG00000074771 NADPH oxidase 3 6 155395370-155455903 Predicted membrane proteins, Transporters Evidence at protein level HPA073837 Uncertain Vesicles Not detected Not detected adrenal gland: 0.1 Cell line enriched 7 MCF7: 2.9 +ENO1 ENO1L1, MBP-1, MPB1, PPH ENSG00000074800 Enolase 1 1 8861002-8879249 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018614, HPA068284, HPA068721, CAB069394 Enhanced Enhanced Plasma membrane
Cytosol Liver cancer:1.30e-8 (unfavourable), Glioma:2.12e-4 (unfavourable) Expressed in all Expressed in all appendix: 768.2 Expressed in all +SLC12A1 NKCC2 ENSG00000074803 Solute carrier family 12 member 1 15 48191664-48304078 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA014967, HPA018107 Enhanced Approved Nucleus
Vesicles Tissue enhanced Tissue enriched 477 kidney: 780.2 testis: 1.6 Cell line enriched 19 RPTEC TERT1: 19.2 +MYDGF C19orf10, IL-25, IL-27, IL25, IL27, IL27w, R33729_1, SF20 ENSG00000074842 Myeloid derived growth factor 19 4641374-4670370 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041872, HPA046744 Approved Renal cancer:4.99e-12 (unfavourable), Endometrial cancer:6.50e-7 (favourable) Expressed in all Expressed in all epididymis: 134.0 Expressed in all +ANO8 KIAA1623, TMEM16H ENSG00000074855 Anoctamin 8 19 17323223-17334829 Predicted membrane proteins Evidence at protein level HPA031787, HPA049206 Uncertain Uncertain Nucleoplasm
Nucleoli fibrillar center Expressed in all Tissue enhanced cerebral cortex: 34.5 skin: 19.9 Mixed +TUBE1 dJ142L7.2, FLJ22589, TUBE ENSG00000074935 Tubulin epsilon 1 6 112070777-112087529 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA032073, HPA032074 Approved Expressed in all Expressed in all testis: 55.3 Expressed in all +ARHGEF10L FLJ10521, KIAA1626 ENSG00000074964 Rho guanine nucleotide exchange factor 10 like 1 17539835-17697874 Predicted intracellular proteins Evidence at protein level HPA026426, HPA026440, HPA028115 Approved Approved Golgi apparatus
Vesicles
Cytosol Head and neck cancer:8.13e-5 (favourable), Renal cancer:5.65e-4 (favourable) Expressed in all Expressed in all thyroid gland: 29.7 Mixed +TXK BTKL, PSCTK5, PTK4, RLK, TKL ENSG00000074966 TXK tyrosine kinase 4 48066393-48134256 Enzymes, Predicted intracellular proteins Evidence at protein level HPA062482 Approved Vesicles Mixed Tissue enhanced lymph node: 17.9 epididymis: 15.1 Cell line enhanced HMC-1: 12.2;WM-115: 31.5 +WSCD2 KIAA0789 ENSG00000075035 WSC domain containing 2 12 108129471-108250537 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA013346, HPA048133 Approved Approved Nucleoplasm Tissue enhanced Group enriched 5 cerebral cortex: 14.1;cervix, uterine: 5.8;endometrium: 8.6;prostate: 7.1;seminal vesicle: 19.0;smooth muscle: 10.4;thyroid gland: 28.8 urinary bladder: 2.6 Cell line enriched 20 RT4: 26.6 +KCNQ2 BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, Kv7.2 ENSG00000075043 Potassium voltage-gated channel subfamily Q member 2 20 63400210-63472677 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA016642, HPA057112 Enhanced Approved Endoplasmic reticulum Tissue enriched Tissue enriched 7 cerebral cortex: 57.2 testis: 8.2 Cell line enhanced AN3-CA: 32.4;SCLC-21H: 79.6;SH-SY5Y: 126.1 +TACR2 NK2R, NKNAR, SKR, TAC2R ENSG00000075073 Tachykinin receptor 2 10 69403903-69416867 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA076573 Approved Plasma membrane Tissue enhanced Tissue enhanced smooth muscle: 67.2 esophagus: 23.1 Cell line enhanced SK-MEL-30: 3.2;U-87 MG: 2.3 +ACTR6 ARP6, FLJ13433 ENSG00000075089 ARP6 actin-related protein 6 homolog 12 100199122-100241865 Predicted intracellular proteins Evidence at protein level HPA038587, HPA038588 Uncertain Approved Plasma membrane
Cytosol Liver cancer:7.70e-9 (unfavourable) Expressed in all Mixed testis: 16.2 Expressed in all +TIPIN FLJ20516 ENSG00000075131 TIMELESS interacting protein 15 66336206-66386746 Predicted intracellular proteins Evidence at protein level HPA039704, HPA058799 Enhanced Supported Nucleus
Vesicles Liver cancer:2.47e-4 (unfavourable), Cervical cancer:4.15e-4 (favourable), Prostate cancer:9.35e-4 (unfavourable) Expressed in all Tissue enhanced testis: 36.9 parathyroid gland: 12.6 Expressed in all +SRI ENSG00000075142 Sorcin 7 88205118-88226993 Predicted intracellular proteins Evidence at protein level HPA019004, HPA073666 Enhanced Supported Nucleoplasm
Cytosol Lung cancer:3.08e-4 (favourable), Pancreatic cancer:9.03e-4 (unfavourable) Expressed in all Expressed in all colon: 562.9 Mixed +EIF4G3 eIF4GII ENSG00000075151 Eukaryotic translation initiation factor 4 gamma 3 1 20806292-21176888 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025031, HPA025039, HPA025041 Enhanced Approved Cytosol Liver cancer:9.60e-7 (unfavourable) Expressed in all Expressed in all testis: 170.1 Mixed +NUP37 FLJ22618, MGC5585 ENSG00000075188 Nucleoporin 37 12 102073103-102120124 Predicted intracellular proteins, Transporters Evidence at protein level HPA056300, HPA073708 Enhanced Supported Nucleoplasm Liver cancer:7.70e-6 (unfavourable), Head and neck cancer:6.72e-4 (unfavourable) Expressed in all Expressed in all lymph node: 32.2 Expressed in all +SEMA3A coll-1, Hsema-I, SEMA1, SEMAD, SemD ENSG00000075213 Semaphorin 3A 7 83955777-84492724 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029447, HPA052235 Approved Approved Nucleoplasm
Vesicles Cervical cancer:2.69e-5 (unfavourable) Mixed Mixed placenta: 14.5 Cell line enhanced AF22: 127.3;BJ: 86.5;fHDF/TERT166: 86.7 +GTSE1 B99, GTSE-1 ENSG00000075218 G2 and S-phase expressed 1 22 46296741-46330810 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029457, HPA060544 Uncertain Approved Plasma membrane
Centrosome Liver cancer:1.90e-10 (unfavourable), Pancreatic cancer:1.29e-4 (unfavourable), Lung cancer:4.66e-4 (unfavourable) Mixed Tissue enhanced testis: 12.5 lymph node: 10.6 Mixed +SEMA3C SEMAE, SemE ENSG00000075223 Semaphorin 3C 7 80742538-80922359 Predicted secreted proteins Evidence at protein level HPA042418 Uncertain Approved Golgi apparatus
Plasma membrane
Cytosol Pancreatic cancer:4.08e-5 (unfavourable), Head and neck cancer:5.72e-5 (unfavourable) Mixed Mixed prostate: 103.0 Cell line enhanced T-47d: 248.8;U-2197: 317.7 +TTC38 FLJ20699 ENSG00000075234 Tetratricopeptide repeat domain 38 22 46267961-46294008 Predicted intracellular proteins Evidence at protein level HPA029302 Approved Approved Cytosol Endometrial cancer:3.21e-6 (favourable) Expressed in all Expressed in all small intestine: 88.3 Mixed +ACAT1 ACAT, THIL ENSG00000075239 Acetyl-CoA acetyltransferase 1 11 108121516-108147776 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004428, HPA007569 Enhanced Enhanced Mitochondria Renal cancer:0.00e+0 (favourable), Liver cancer:1.43e-5 (favourable) Expressed in all Expressed in all kidney: 534.2 Expressed in all +GRAMD4 DIP, KIAA0767 ENSG00000075240 GRAM domain containing 4 22 46576012-46679790 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Head and neck cancer:3.04e-4 (favourable) Expressed in all Expressed in all skin: 53.4 Expressed in all +CELSR1 ADGRC1, CDHF9, FMI2, HFMI2, ME2 ENSG00000075275 Cadherin EGF LAG seven-pass G-type receptor 1 22 46360834-46537170 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA052976, HPA060521 Supported Plasma membrane Expressed in all Mixed fallopian tube: 15.5 Cell line enhanced A549: 38.6;T-47d: 28.3 +WNT8B ENSG00000075290 Wnt family member 8B 10 100463041-100483744 Predicted secreted proteins Evidence at transcript level HPA036570 Uncertain Not detected Tissue enhanced adrenal gland: 1.1;parathyroid gland: 1.5;testis: 1.2 kidney: 0.6 Cell line enhanced AF22: 2.3;SCLC-21H: 1.3 +ZNF638 MGC26130, NP220, ZFML, Zfp638 ENSG00000075292 Zinc finger protein 638 2 71276561-71435069 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036784, HPA057395 Supported Enhanced Nucleoplasm
Vesicles Urothelial cancer:8.73e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 58.9 Expressed in all +SLC25A40 MCFP ENSG00000075303 Solute carrier family 25 member 40 7 87833568-87876357 Predicted membrane proteins, Transporters Evidence at protein level HPA055197 Uncertain Renal cancer:1.52e-5 (favourable), Liver cancer:1.93e-4 (unfavourable) Expressed in all Mixed prostate: 14.1 Expressed in all +TIMM21 C18orf55, HSPC154, TIM21 ENSG00000075336 Translocase of inner mitochondrial membrane 21 18 74148511-74160530 Predicted membrane proteins Evidence at protein level HPA010587, HPA051543 Uncertain Approved Nucleoplasm Renal cancer:1.38e-9 (favourable), Liver cancer:9.22e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 26.2 Expressed in all +ADD2 ADDB ENSG00000075340 Adducin 2 2 70607618-70768225 Predicted intracellular proteins Evidence at protein level CAB009796, HPA034509, HPA034510 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced Group enriched 10 bone marrow: 40.2;cerebral cortex: 44.7 testis: 4.2 Cell line enhanced K-562: 41.5;NTERA-2: 86.7;SCLC-21H: 50.4;U-251 MG: 38.9 +FGF4 HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF ENSG00000075388 Fibroblast growth factor 4 11 69771016-69775403 Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA011209 Uncertain Tissue enriched Not detected testis: 0.4 Cell line enriched 90 NTERA-2: 15.7 +RASAL2 nGAP ENSG00000075391 RAS protein activator like 2 1 178094141-178484147 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA018805, HPA020453 Enhanced Approved Plasma membrane
Focal adhesion sites Urothelial cancer:2.05e-4 (unfavourable) Expressed in all Mixed esophagus: 19.4 Mixed +VPS9D1 ATP-BL, C16orf7 ENSG00000075399 VPS9 domain containing 1 16 89707134-89720986 Predicted intracellular proteins Evidence at protein level HPA007847, HPA023620 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:2.91e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 26.4 Mixed +ZNF37A KOX21, ZNF37 ENSG00000075407 Zinc finger protein 37A 10 38094334-38150293 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003172 Approved Approved Vesicles Renal cancer:2.31e-4 (unfavourable), Liver cancer:2.83e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 18.1 Expressed in all +MARK3 CTAK1, KP78, PAR-1A ENSG00000075413 Microtubule affinity regulating kinase 3 14 103385392-103503831 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024652 Approved Approved Nuclear membrane Melanoma:1.14e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 64.0 Expressed in all +SLC25A3 PHC ENSG00000075415 Solute carrier family 25 member 3 12 98593591-98606379 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA045709 Supported Mitochondria Renal cancer:8.11e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 595.7 Expressed in all +FNDC3B DKFZp762K137, FAD104, FLJ23399, PRO4979, YVTM2421 ENSG00000075420 Fibronectin type III domain containing 3B 3 172039628-172401665 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007859 Uncertain Approved Endoplasmic reticulum Renal cancer:5.65e-7 (unfavourable), Cervical cancer:2.41e-5 (unfavourable), Pancreatic cancer:9.06e-5 (unfavourable), Liver cancer:9.85e-4 (unfavourable) Expressed in all Expressed in all placenta: 77.5 Expressed in all +FOSL2 FLJ23306, FRA2 ENSG00000075426 FOS like 2, AP-1 transcription factor subunit 2 28392448-28417312 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004817, CAB013460, HPA061417 Supported Enhanced Nucleus Expressed in all Expressed in all adrenal gland: 224.8 Mixed +CACNG5 ENSG00000075429 Calcium voltage-gated channel auxiliary subunit gamma 5 17 66835117-66885486 Predicted membrane proteins Evidence at protein level HPA050115 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 1.2 lymph node: 0.6 Not detected +CACNG4 MGC11138, MGC24983 ENSG00000075461 Calcium voltage-gated channel auxiliary subunit gamma 4 17 66964910-67033398 Predicted membrane proteins, Transporters Evidence at protein level HPA005803, HPA065370 Enhanced Approved Cytosol Mixed Tissue enhanced cerebral cortex: 48.6;prostate: 20.3 lung: 9.2 Cell line enriched 7 SH-SY5Y: 436.5 +FRYL AF4p12, DKFZp686E205, KIAA0826, MOR2 ENSG00000075539 FRY like transcription coactivator 4 48497361-48780322 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031106, HPA031107 Supported Approved Microtubules
Cytokinetic bridge
Cytosol Expressed in all Expressed in all parathyroid gland: 51.2 Expressed in all +TMEM131 CC28, KIAA0257, PRO1048, RW1, YR-23 ENSG00000075568 Transmembrane protein 131 2 97756333-97995891 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017678, HPA017682 Approved Uncertain Vesicles
Intermediate filaments Expressed in all Expressed in all parathyroid gland: 47.6 Expressed in all +FSCN1 FLJ38511, p55, SNL ENSG00000075618 Fascin actin-bundling protein 1 7 5592823-5606655 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000121, HPA005723, CAB035991, HPA050654 Enhanced Supported Plasma membrane
Cytosol Renal cancer:8.15e-7 (unfavourable), Lung cancer:2.28e-4 (unfavourable), Head and neck cancer:5.76e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 85.5 spleen: 54.6 Cell line enhanced BEWO: 579.4 +ACTB ENSG00000075624 Actin beta 7 5527151-5563784 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002621, HPA041264, HPA041271 Supported Renal cancer:3.78e-5 (unfavourable), Head and neck cancer:4.51e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 7221.8 Expressed in all +MOCOS FLJ20733, HMCS, MOS ENSG00000075643 Molybdenum cofactor sulfurase 18 36187519-36272157 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039412, HPA047958 Uncertain Supported Mitochondria
Cytosol Renal cancer:3.03e-12 (unfavourable), Pancreatic cancer:1.29e-4 (unfavourable), Lung cancer:3.55e-4 (unfavourable) Mixed Mixed adrenal gland: 11.4 Cell line enhanced hTERT-HME1: 38.4;SiHa: 58.4;SK-MEL-30: 30.1 +PLD1 ENSG00000075651 Phospholipase D1 3 171600405-171810950 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004527, HPA042396 Enhanced Approved Plasma membrane Urothelial cancer:4.76e-6 (unfavourable) Expressed in all Tissue enhanced gallbladder: 138.3 small intestine: 49.2 Cell line enhanced HUVEC TERT2: 49.2;TIME: 42.2 +ATP12A #945, 2, ATP1AL1, HK ENSG00000075673 ATPase H+/K+ transporting non-gastric alpha2 subunit 13 24680411-24712493 Enzymes, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039526 Approved Tissue enhanced Tissue enhanced esophagus: 12.7;placenta: 8.2;tonsil: 14.1 skin: 7.1 Not detected +WDR62 C19orf14, DKFZP434J046, FLJ33298, MCPH2 ENSG00000075702 WD repeat domain 62 19 36054881-36105106 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043255, HPA043639, CAB046468 Enhanced Enhanced Microtubule organizing center
Cytosol Mixed Group enriched 8 skeletal muscle: 15.9;testis: 76.4 heart muscle: 6.0 Mixed +DLG1 dJ1061C18.1.1, DLGH1, hdlg, SAP-97, SAP97 ENSG00000075711 Discs large MAGUK scaffold protein 1 3 197042560-197299300 Predicted intracellular proteins Evidence at protein level CAB016307, HPA069593 Supported Uncertain Vesicles
Plasma membrane Expressed in all Expressed in all thyroid gland: 94.9 Expressed in all +RAB7A RAB7 ENSG00000075785 RAB7A, member RAS oncogene family 3 128726122-128814796 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006964, CAB037131 Supported Supported Lysosomes Liver cancer:9.89e-6 (unfavourable), Endometrial cancer:1.52e-4 (unfavourable), Pancreatic cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 270.2 Expressed in all +BCAP29 BAP29, DKFZp686M2086 ENSG00000075790 B-cell receptor associated protein 29 7 107579977-107629170 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA029215, HPA049694 Enhanced Approved Cytosol Liver cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 93.0 Expressed in all +SEC31B DKFZP434M183, SEC31B-1, SEC31L2 ENSG00000075826 SEC31 homolog B, COPII coat complex component 10 100486642-100519864 Predicted intracellular proteins Evidence at protein level HPA035882, HPA040819, HPA060052 Uncertain Approved Nucleus
Nucleoli
Vesicles
Cytosol Renal cancer:6.41e-7 (unfavourable) Mixed Mixed testis: 3.2 Mixed +SART3 KIAA0156, p110, RP11-13G14, TIP110 ENSG00000075856 Squamous cell carcinoma antigen recognized by T-cells 3 12 108522580-108561400 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044322 Approved Liver cancer:6.32e-6 (unfavourable), Melanoma:8.74e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.9 Expressed in all +ARHGAP15 BM046 ENSG00000075884 Rho GTPase activating protein 15 2 143091362-143768352 Predicted intracellular proteins Evidence at protein level HPA032125 Uncertain Uncertain Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:6.95e-5 (unfavourable) Mixed Tissue enhanced lymph node: 65.4 spleen: 59.6 Cell line enhanced HEL: 77.1;HL-60: 97.4;MOLT-4: 65.5;NB-4: 59.8;THP-1: 85.7;U-698: 65.7 +TUBA3D H2-ALPHA ENSG00000075886 Tubulin alpha 3d 2 131476093-131482934 Predicted intracellular proteins Evidence at protein level CAB004972, HPA039247, HPA043684, HPA063394 Uncertain Supported Microtubules Renal cancer:4.75e-9 (unfavourable), Breast cancer:4.65e-4 (favourable) Mixed Tissue enriched 31 testis: 250.3 epididymis: 8.1 Not detected +PAX2 ENSG00000075891 Paired box 2 10 100735603-100829941 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level CAB013024, HPA047704, HPA070751 Enhanced Supported Nucleoli
Golgi apparatus Endometrial cancer:4.56e-4 (unfavourable) Group enriched Group enriched 5 epididymis: 37.1;fallopian tube: 19.0;kidney: 25.3;seminal vesicle: 20.0 cervix, uterine: 4.9 Group enriched 8 AN3-CA: 16.6;EFO-21: 23.1;RPTEC TERT1: 13.3 +EXOSC7 EAP1, hRrp42p, KIAA0116, p8, RRP42, Rrp42p ENSG00000075914 Exosome component 7 3 44975241-45036066 Predicted intracellular proteins Evidence at protein level HPA036182, HPA057980 Approved Supported Nuclear speckles Renal cancer:2.69e-4 (favourable) Expressed in all Expressed in all adrenal gland: 44.9 Expressed in all +KIFAP3 FLA3, KAP-1, KAP3, SMAP ENSG00000075945 Kinesin associated protein 3 1 169921326-170085208 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023738, HPA023742 Supported Expressed in all Expressed in all cerebral cortex: 106.0 Expressed in all +MKRN2 HSPC070, RNF62 ENSG00000075975 Makorin ring finger protein 2 3 12557014-12583713 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037559, HPA037560 Enhanced Approved Nucleoplasm
Cytosol Liver cancer:1.58e-4 (unfavourable), Renal cancer:6.04e-4 (favourable) Expressed in all Expressed in all testis: 100.1 Expressed in all +MCM6 Mis5 ENSG00000076003 Minichromosome maintenance complex component 6 2 135839626-135876426 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004818, CAB009577 Enhanced Enhanced Nucleoplasm Renal cancer:8.29e-12 (unfavourable), Liver cancer:5.70e-7 (unfavourable), Melanoma:1.09e-5 (unfavourable) Expressed in all Mixed lymph node: 40.7 Expressed in all +REXO2 CGI-114, DKFZP566E144, SFN ENSG00000076043 RNA exonuclease 2 11 114439386-114450279 Predicted intracellular proteins Evidence at protein level HPA038450, HPA038451 Enhanced Supported Nucleoli
Focal adhesion sites
Mitochondria Colorectal cancer:6.51e-4 (favourable), Urothelial cancer:6.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 259.4 Expressed in all +RBM7 ENSG00000076053 RNA binding motif protein 7 11 114400030-114414203 Predicted intracellular proteins Evidence at protein level HPA013993, HPA048003 Supported Enhanced Nucleoplasm Pancreatic cancer:1.17e-4 (unfavourable), Colorectal cancer:6.14e-4 (favourable) Expressed in all Expressed in all bone marrow: 40.8 Expressed in all +RBMS2 SCR3 ENSG00000076067 RNA binding motif single stranded interacting protein 2 12 56521929-56596196 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039225, HPA058784 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Renal cancer:3.22e-4 (favourable) Expressed in all Expressed in all lung: 37.9 Mixed +BAZ2A KIAA0314, TIP5, WALp3 ENSG00000076108 Bromodomain adjacent to zinc finger domain 2A 12 56595596-56636816 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005782, HPA063806 Enhanced Nuclear speckles Liver cancer:2.72e-4 (unfavourable) Expressed in all Expressed in all testis: 82.7 Expressed in all +PTPN23 DKFZP564F0923, HD-PTP, KIAA1471 ENSG00000076201 Protein tyrosine phosphatase, non-receptor type 23 3 47381011-47413441 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016845 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:1.82e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.9 Expressed in all +MLH1 COCA2, FCC2, HNPCC, HNPCC2 ENSG00000076242 MutL homolog 1 3 36993332-37050918 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013294, HPA052707, HPA060714, CAB070868 Supported Enhanced Nucleoplasm Liver cancer:8.24e-5 (unfavourable) Expressed in all Expressed in all testis: 60.0 Mixed +UNG DGU, HIGM4, UDG, UNG1, UNG2 ENSG00000076248 Uracil DNA glycosylase 12 109097574-109110992 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB011605 Uncertain Approved Cytosol Melanoma:3.06e-4 (unfavourable), Liver cancer:6.40e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 56.2 Expressed in all +FMO4 FMO2 ENSG00000076258 Flavin containing monooxygenase 4 1 171314208-171342084 Enzymes, Predicted membrane proteins Evidence at protein level HPA049100 Uncertain Liver cancer:1.09e-4 (favourable), Renal cancer:6.96e-4 (favourable), Lung cancer:7.45e-4 (favourable) Expressed in all Tissue enhanced kidney: 48.2;liver: 30.1 parathyroid gland: 10.9 Cell line enhanced EFO-21: 5.2 +KLHL20 KHLHX, KLEIP ENSG00000076321 Kelch like family member 20 1 173714941-173786702 Predicted intracellular proteins Evidence at protein level HPA025034, HPA053704 Approved Supported Golgi apparatus
Cytosol Expressed in all Expressed in all testis: 29.3 Expressed in all +RGS11 ENSG00000076344 Regulator of G-protein signaling 11 16 268301-275980 Predicted intracellular proteins Evidence at protein level HPA041692, HPA043039 Uncertain Pancreatic cancer:1.24e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 20.3 adipose tissue: 8.1 Cell line enhanced HHSteC: 2.6;SCLC-21H: 3.6;SH-SY5Y: 2.5;T-47d: 2.4 +SLC46A1 HCP1, MGC9564, PCFT ENSG00000076351 Solute carrier family 46 member 1 17 28394756-28407197 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB011614 Approved Supported Plasma membrane
Cytosol Glioma:3.90e-4 (unfavourable) Expressed in all Expressed in all duodenum: 95.1 Cell line enhanced CACO-2: 169.5 +PLXNA2 FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2 ENSG00000076356 Plexin A2 1 208022242-208244320 Predicted membrane proteins Evidence at protein level CAB009763 Approved Expressed in all Mixed ovary: 17.0 Cell line enhanced BEWO: 51.1;HaCaT: 49.2;HUVEC TERT2: 58.9;TIME: 133.3 +SPAG5 DEEPEST, hMAP126, MAP126 ENSG00000076382 Sperm associated antigen 5 17 28577565-28599279 Predicted intracellular proteins Evidence at protein level HPA022008, HPA022479 Approved Renal cancer:5.43e-13 (unfavourable), Liver cancer:5.43e-5 (unfavourable), Pancreatic cancer:3.02e-4 (unfavourable) Expressed in all Tissue enhanced testis: 120.0 kidney: 25.1 Mixed +ANKRD13A ANKRD13, NY-REN-25 ENSG00000076513 Ankyrin repeat domain 13A 12 109999186-110039763 Predicted intracellular proteins Evidence at protein level HPA039488, HPA043218 Enhanced Supported Plasma membrane Head and neck cancer:7.70e-6 (favourable), Ovarian cancer:6.77e-4 (unfavourable) Expressed in all Expressed in all testis: 113.4 Expressed in all +TPD52 D52, hD52, N8L ENSG00000076554 Tumor protein D52 8 80034745-80231232 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028427, HPA062167 Enhanced Approved Golgi apparatus
Cytosol Renal cancer:4.77e-6 (unfavourable), Breast cancer:1.11e-5 (unfavourable) Expressed in all Expressed in all prostate: 168.9 Cell line enhanced SK-BR-3: 428.2 +ACACB ACC2, ACCB, HACC275 ENSG00000076555 Acetyl-CoA carboxylase beta 12 109116595-109268226 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006554 Enhanced Renal cancer:1.15e-5 (favourable), Pancreatic cancer:1.93e-4 (favourable) Expressed in all Tissue enriched 6 adipose tissue: 194.8 parathyroid gland: 30.6 Cell line enriched 13 ASC diff: 152.8 +TRAF4 CART1, MLN62, RNF83 ENSG00000076604 TNF receptor associated factor 4 17 28743984-28750958 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052377 Enhanced Expressed in all Mixed duodenum: 47.2 Expressed in all +PAG1 CBP, PAG ENSG00000076641 Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 8 80967810-81112068 Predicted intracellular proteins Evidence at protein level HPA001632, HPA066527 Uncertain Supported Vesicles
Plasma membrane Renal cancer:1.24e-6 (unfavourable), Testis cancer:6.82e-4 (unfavourable) Expressed in all Mixed placenta: 23.0 Cell line enhanced Daudi: 25.3;HMC-1: 40.0;SK-MEL-30: 28.4 +GPATCH1 ECGP, FLJ10206, FLJ38686, GPATC1 ENSG00000076650 G-patch domain containing 1 19 33080880-33130542 Predicted intracellular proteins Evidence at protein level HPA043430, HPA043604 Approved Uncertain Nucleoplasm
Plasma membrane
Cell Junctions Endometrial cancer:8.20e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 8.8 Expressed in all +ICAM3 CD50, CDW50, ICAM-R ENSG00000076662 Intercellular adhesion molecule 3 19 10333776-10339823 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002498, HPA049820 Enhanced Approved Nucleus
Nuclear membrane
Mitochondria Mixed Expressed in all bone marrow: 111.9 Cell line enhanced Karpas-707: 205.5;NB-4: 121.3;RPMI-8226: 154.3;U-937: 121.2 +NT5C2 cN-II, GMP, NT5B, PNT5, SPG65 ENSG00000076685 5'-nucleotidase, cytosolic II 10 103088017-103193306 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003751 Approved Expressed in all Expressed in all thyroid gland: 119.6 Expressed in all +MCAM CD146, MUC18 ENSG00000076706 Melanoma cell adhesion molecule 11 119308529-119321521 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002147, HPA008848 Enhanced Enhanced Plasma membrane Renal cancer:5.14e-4 (unfavourable), Cervical cancer:7.61e-4 (unfavourable) Expressed in all Mixed adipose tissue: 367.1 Cell line enhanced HUVEC TERT2: 935.6;TIME: 901.7;WM-115: 859.1 +GPC4 K-glypican ENSG00000076716 Glypican 4 X 133300103-133415490 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA030836 Approved Approved Vesicles Renal cancer:1.25e-5 (favourable), Lung cancer:3.51e-4 (favourable) Expressed in all Mixed placenta: 41.7 Cell line enhanced AF22: 206.9;HAP1: 125.3;NTERA-2: 110.1;RPTEC TERT1: 208.8 +MBNL3 CHCR, FLJ11316, MBLX39, MBXL ENSG00000076770 Muscleblind like splicing regulator 3 X 132369317-132489968 Predicted intracellular proteins Evidence at protein level HPA001584 Enhanced Approved Golgi apparatus
Vesicles Endometrial cancer:1.57e-4 (unfavourable) Expressed in all Group enriched 5 placenta: 242.1;testis: 81.4 liver: 30.6 Cell line enhanced CACO-2: 102.2;Hep G2: 116.6 +CAMSAP3 KIAA1543, Nezha, PPP1R80 ENSG00000076826 Calmodulin regulated spectrin associated protein family member 3 19 7595902-7618304 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043830, HPA062149 Enhanced Approved Nucleoplasm
Centrosome Renal cancer:7.55e-7 (favourable) Expressed in all Tissue enhanced skin: 22.1 duodenum: 15.2 Cell line enhanced CACO-2: 22.2 +RAP1GAP KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII ENSG00000076864 RAP1 GTPase activating protein 1 21596215-21669363 Predicted intracellular proteins Evidence at protein level HPA001922, CAB003851 Enhanced Supported Approved Cytosol Renal cancer:1.12e-6 (favourable), Liver cancer:5.85e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 122.1;thyroid gland: 232.8 adrenal gland: 93.2 Cell line enhanced A549: 41.8;K-562: 26.3;SCLC-21H: 61.3 +XAB2 HCNP, HCRN, NTC90, SYF1 ENSG00000076924 XPA binding protein 2 19 7619525-7629565 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048751 Approved Nucleus
Vesicles Cervical cancer:4.04e-4 (favourable), Endometrial cancer:4.96e-4 (favourable), Pancreatic cancer:7.47e-4 (favourable) Expressed in all Expressed in all testis: 39.3 Expressed in all +ARHGEF1 LBCL2, P115-RHOGEF, SUB1.5 ENSG00000076928 Rho guanine nucleotide exchange factor 1 19 41883161-41930150 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009502, HPA012924, HPA060784 Enhanced Enhanced Plasma membrane
Cytosol Renal cancer:3.36e-8 (unfavourable), Breast cancer:5.92e-4 (favourable) Expressed in all Expressed in all lymph node: 144.9 Expressed in all +STXBP2 Hunc18b, UNC18B ENSG00000076944 Syntaxin binding protein 2 19 7636881-7647873 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015564, HPA063868 Approved Enhanced Cytosol Urothelial cancer:5.13e-6 (favourable), Endometrial cancer:2.29e-4 (favourable), Liver cancer:4.65e-4 (unfavourable), Thyroid cancer:7.68e-4 (favourable) Expressed in all Mixed bone marrow: 125.3 Mixed +MAP2K7 Jnkk2, MKK7, PRKMK7 ENSG00000076984 Mitogen-activated protein kinase kinase 7 19 7903843-7914478 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001633, CAB004262, HPA064711 Supported Approved Golgi apparatus
Plasma membrane
Cytosol Head and neck cancer:8.54e-5 (favourable), Urothelial cancer:1.56e-4 (favourable) Expressed in all Expressed in all spleen: 19.1 Expressed in all +NMRK2 ITGB1BP3, MIBP, NRK2 ENSG00000077009 Nicotinamide riboside kinase 2 19 3933103-3942416 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049909, HPA054792, HPA072450 Approved Enhanced Nucleoplasm
Vesicles Renal cancer:1.19e-4 (favourable) Tissue enhanced Group enriched 49 heart muscle: 374.4;skeletal muscle: 218.4 esophagus: 6.1 Group enriched 9 BEWO: 28.1;NTERA-2: 24.3 +DGKD DGKdelta, KIAA0145 ENSG00000077044 Diacylglycerol kinase delta 2 233354507-233472104 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027530, HPA049101 Approved Supported Cytosol Renal cancer:4.07e-8 (unfavourable), Liver cancer:1.69e-5 (unfavourable) Expressed in all Mixed testis: 20.8 Expressed in all +CTTNBP2 C7orf8, CORTBP2, KIAA1758, Orf4 ENSG00000077063 Cortactin binding protein 2 7 117710651-117874139 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009151, HPA044654 Enhanced Approved Midbody ring
Cytosol Renal cancer:3.71e-5 (favourable) Mixed Mixed parathyroid gland: 19.1 Group enriched 6 HEL: 50.6;HMC-1: 63.2 +ACTL6B ACTL6, BAF53B ENSG00000077080 Actin like 6B 7 100643097-100656461 Predicted intracellular proteins Evidence at protein level HPA045126 Uncertain Approved Nucleoli Group enriched Tissue enriched 19 cerebral cortex: 45.6 adrenal gland: 2.4 Group enriched 92 SCLC-21H: 33.1;SH-SY5Y: 30.4 +RARB HAP, NR1B2, RRB2 ENSG00000077092 Retinoic acid receptor beta 3 25174332-25597932 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002617, HPA004174 Enhanced Enhanced Nucleoplasm Renal cancer:3.43e-5 (favourable) Expressed in all Mixed placenta: 20.6 Cell line enhanced HEK 293: 14.7;HUVEC TERT2: 11.2;WM-115: 36.1 +TOP2B ENSG00000077097 Topoisomerase (DNA) II beta 3 25597905-25664907 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004601, HPA024120, HPA050441 Supported Enhanced Nucleus Liver cancer:1.86e-7 (unfavourable), Renal cancer:2.43e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 107.4 Expressed in all +TM9SF3 SMBP ENSG00000077147 Transmembrane 9 superfamily member 3 10 96518109-96587452 Predicted membrane proteins Evidence at protein level HPA039609 Approved Approved Golgi apparatus
Vesicles Expressed in all Expressed in all stomach: 180.7 Expressed in all +NFKB2 LYT-10, NF-kB2, p105, p49/p100, p52 ENSG00000077150 Nuclear factor kappa B subunit 2 10 102394110-102402529 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008422, CAB022098, HPA023900 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:6.69e-12 (unfavourable), Melanoma:8.45e-5 (favourable), Colorectal cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all appendix: 70.7 Expressed in all +UBE2T FANCT, HSPC150 ENSG00000077152 Ubiquitin conjugating enzyme E2 T 1 202331657-202341980 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002831 Approved Nucleus
Nucleoli Renal cancer:2.22e-16 (unfavourable), Liver cancer:4.79e-6 (unfavourable), Ovarian cancer:6.90e-6 (favourable) Expressed in all Mixed testis: 36.0 Expressed in all +PPP1R12B MGC131980, MGC87886, MYPT2, PP1bp55 ENSG00000077157 Protein phosphatase 1 regulatory subunit 12B 1 202348699-202592706 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024171, HPA024640 Enhanced Supported Plasma membrane
Actin filaments Expressed in all Expressed in all endometrium: 366.8 Mixed +DNAJC10 ERdj5, PDIA19 ENSG00000077232 DnaJ heat shock protein family (Hsp40) member C10 2 182716041-182794464 Predicted membrane proteins Evidence at protein level HPA031111 Approved Renal cancer:2.19e-7 (unfavourable), Endometrial cancer:6.42e-5 (favourable), Thyroid cancer:7.27e-4 (unfavourable) Expressed in all Expressed in all epididymis: 154.9 Expressed in all +GTF3C1 TFIIIC220 ENSG00000077235 General transcription factor IIIC subunit 1 16 27459555-27549913 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051617 Approved Supported Nucleus
Nucleoli Renal cancer:1.25e-4 (favourable), Liver cancer:8.73e-4 (unfavourable), Pancreatic cancer:9.56e-4 (favourable) Expressed in all Expressed in all thyroid gland: 49.8 Expressed in all +IL4R CD124 ENSG00000077238 Interleukin 4 receptor 16 27313668-27364778 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004451, HPA050124 Enhanced Renal cancer:1.23e-5 (unfavourable), Endometrial cancer:6.43e-4 (favourable) Expressed in all Expressed in all lymph node: 137.6 Mixed +USP33 KIAA1097, VDU1 ENSG00000077254 Ubiquitin specific peptidase 33 1 77695987-77759852 Enzymes, Predicted intracellular proteins Evidence at protein level HPA005719 Uncertain Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 55.5 Expressed in all +PAK3 bPAK, hPAK3, MRX30, MRX47 ENSG00000077264 P21 (RAC1) activated kinase 3 X 110944285-111227361 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA044791, HPA060219 Approved Approved Cytosol Mixed Tissue enhanced cerebral cortex: 34.3 thyroid gland: 10.4 Cell line enhanced EFO-21: 10.2;HAP1: 10.2;HDLM-2: 11.9;NTERA-2: 9.6;SCLC-21H: 14.7;U-251 MG: 11.1 +CAPN6 CalpM, CANPX, CAPNX ENSG00000077274 Calpain 6 X 111245103-111270523 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA040383 Uncertain Cytosol Tissue enhanced Tissue enhanced epididymis: 255.9;placenta: 117.0;seminal vesicle: 100.4 endometrium: 37.2 Group enriched 9 HAP1: 3.4;HDLM-2: 9.9;NTERA-2: 16.1 +DCX DBCN, DC, LISX, SCLH, XLIS ENSG00000077279 Doublecortin X 111293779-111412429 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036121 Supported Approved Cytosol Tissue enriched Tissue enhanced cerebral cortex: 10.6 endometrium: 2.4 Group enriched 9 SCLC-21H: 65.0;SH-SY5Y: 24.0 +SNRPA Mud1, U1-A, U1A ENSG00000077312 Small nuclear ribonucleoprotein polypeptide A 19 40750637-40765389 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004652, HPA046440, HPA054834 Enhanced Enhanced Nucleoplasm Renal cancer:2.96e-9 (unfavourable), Liver cancer:1.34e-5 (unfavourable), Cervical cancer:2.50e-4 (favourable) Expressed in all Expressed in all lymph node: 60.7 Expressed in all +SPAG6 CT141, pf16, Repro-SA-1 ENSG00000077327 Sperm associated antigen 6 10 22345445-22454224 Predicted intracellular proteins Evidence at protein level HPA038440 Enhanced Mixed Group enriched 12 fallopian tube: 77.7;testis: 172.6 lung: 10.7 Cell line enriched 22 U-937: 82.7 +EXOSC5 hRrp46p, MGC12901, p12B, RRP41B, RRP46, Rrp46p ENSG00000077348 Exosome component 5 19 41386374-41397479 Predicted intracellular proteins Evidence at protein level HPA053150, HPA055677 Approved Enhanced Nucleus
Nucleoli Renal cancer:3.45e-7 (unfavourable) Expressed in all Expressed in all skin: 22.1 Expressed in all +DYNC1I2 DIC74, DNCI2 ENSG00000077380 Dynein cytoplasmic 1 intermediate chain 2 2 171687409-171748420 Predicted intracellular proteins Evidence at protein level CAB033836, HPA040619, HPA053987 Enhanced Supported Nucleoli
Endoplasmic reticulum
Microtubules
Cytosol Renal cancer:8.04e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 146.6 Expressed in all +APBB1IP INAG1, RIAM ENSG00000077420 Amyloid beta precursor protein binding family B member 1 interacting protein 10 26438203-26567803 Predicted intracellular proteins Evidence at protein level HPA017009, HPA063903 Enhanced Enhanced Plasma membrane
Cytosol Endometrial cancer:7.48e-4 (favourable) Expressed in all Mixed appendix: 61.2 Cell line enhanced REH: 169.0;U-698: 134.4 +LRCH4 LRN, LRRN1 ENSG00000077454 Leucine rich repeats and calponin homology domain containing 4 7 100574011-100586153 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA037667, HPA037668 Enhanced Approved Nucleoplasm
Focal adhesion sites
Cytosol Colorectal cancer:1.61e-7 (unfavourable) Expressed in all Expressed in all spleen: 105.8 Expressed in all +FAM76B MGC33371 ENSG00000077458 Family with sequence similarity 76 member B 11 95768942-95790409 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036608 Approved Approved Nucleus
Nucleoli fibrillar center Renal cancer:7.17e-5 (unfavourable), Urothelial cancer:2.72e-4 (favourable) Expressed in all Expressed in all testis: 32.9 Expressed in all +SIRT6 ENSG00000077463 Sirtuin 6 19 4174109-4182604 Predicted intracellular proteins Evidence at protein level HPA049729, HPA071776 Supported Supported Nucleoplasm Urothelial cancer:2.58e-4 (favourable), Endometrial cancer:2.85e-4 (favourable), Stomach cancer:9.13e-4 (favourable) Expressed in all Expressed in all colon: 13.2 Expressed in all +TYR OCA1, OCA1A, OCAIA ENSG00000077498 Tyrosinase 11 89177452-89295759 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB000079, HPA043241, HPA050889 Enhanced Enhanced Vesicles Tissue enriched Tissue enriched 33 skin: 29.8 breast: 0.9 Cell line enriched 1211 SK-MEL-30: 256.2 +POLD3 KIAA0039, P66, P68, PPP1R128 ENSG00000077514 DNA polymerase delta 3, accessory subunit 11 74493851-74669117 Predicted intracellular proteins Evidence at protein level HPA058846 Enhanced Supported Nucleus Renal cancer:7.90e-6 (unfavourable), Melanoma:5.48e-4 (unfavourable), Liver cancer:9.17e-4 (unfavourable) Expressed in all Expressed in all kidney: 45.6 Expressed in all +ACTN2 ENSG00000077522 Actinin alpha 2 1 236686454-236764631 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA006035, HPA008315 Enhanced Tissue enhanced Group enriched 28 heart muscle: 477.5;skeletal muscle: 758.7 esophagus: 22.4 Cell line enhanced HEK 293: 1.8;HSkMC: 5.5;hTEC/SVTERT24-B: 4.9 +CAPZB ENSG00000077549 Capping actin protein of muscle Z-line beta subunit 1 19338776-19485539 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031531, HPA056066 Approved Enhanced Nucleoplasm
Vesicles
Cytosol Liver cancer:1.85e-4 (unfavourable), Renal cancer:3.57e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 490.8 Expressed in all +GPR137B TM7SF1 ENSG00000077585 G protein-coupled receptor 137B 1 236142505-236221865 Predicted membrane proteins, Transporters Evidence at protein level HPA026422 Approved Colorectal cancer:1.63e-4 (unfavourable) Expressed in all Mixed kidney: 70.7 Cell line enhanced SK-MEL-30: 165.8 +NAALAD2 GCPIII, NAALADASE2 ENSG00000077616 N-acetylated alpha-linked acidic dipeptidase 2 11 90131515-90192894 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060820, HPA065419 Approved Approved Nucleus Tissue enhanced Tissue enhanced testis: 27.2 adrenal gland: 13.7 Group enriched 5 CACO-2: 31.5;SH-SY5Y: 13.2 +JADE1 JADE-1, PHF17 ENSG00000077684 Jade family PHD finger 1 4 128809623-128875224 Predicted intracellular proteins Evidence at protein level HPA020016 Approved Approved Mitochondria Renal cancer:8.22e-6 (favourable) Expressed in all Expressed in all thyroid gland: 52.9 Expressed in all +SLC25A43 ENSG00000077713 Solute carrier family 25 member 43 X 119399060-119454478 Predicted membrane proteins, Transporters Evidence at transcript level HPA035188 Uncertain Approved Nucleus Renal cancer:5.06e-8 (unfavourable), Endometrial cancer:3.76e-5 (unfavourable) Expressed in all Mixed esophagus: 20.5 Mixed +UBE2A HHR6A, RAD6A, UBC2 ENSG00000077721 Ubiquitin conjugating enzyme E2 A X 119574467-119591083 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003875, HPA051765, HPA065898 Supported Nucleoplasm
Vesicles
Plasma membrane
Cytosol Renal cancer:2.20e-6 (unfavourable), Cervical cancer:2.16e-4 (favourable), Head and neck cancer:9.07e-4 (unfavourable) Expressed in all Expressed in all placenta: 76.5 Expressed in all +FGFR1 BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM ENSG00000077782 Fibroblast growth factor receptor 1 8 38411138-38468834 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB033614, HPA056402, HPA076274 Approved Supported Nucleoli Expressed in all Expressed in all cervix, uterine: 109.5 Cell line enhanced AN3-CA: 602.2 +FKBP6 FKBP36, PPIase ENSG00000077800 FK506 binding protein 6 7 73328164-73358637 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA061109 Enhanced Tissue enriched Tissue enriched 273 testis: 83.0 parathyroid gland: 0.3 Not detected +SMC1B bK268H5, SMC1L2 ENSG00000077935 Structural maintenance of chromosomes 1B 22 45344063-45413619 Predicted intracellular proteins Evidence at protein level HPA001500 Enhanced Supported Nucleoplasm
Cytosol Tissue enriched Tissue enriched 152 testis: 57.3 lymph node,parathyroid gland: 0.3 Cell line enhanced A-431: 7.8;EFO-21: 3.8;SiHa: 19.3 +FBLN1 FBLN ENSG00000077942 Fibulin 1 22 45502238-45601135 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001612, HPA001613, CAB004393, CAB068187 Enhanced Approved Endoplasmic reticulum Renal cancer:3.02e-10 (unfavourable), Endometrial cancer:9.28e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 1324.4 Cell line enhanced ASC diff: 1263.9;BJ: 870.2;BJ hTERT+: 1319.9;HSkMC: 979.4;RT4: 1182.4 +ITGA8 ENSG00000077943 Integrin subunit alpha 8 10 15513949-15720125 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA003432 Approved Mixed Tissue enhanced prostate: 59.5 seminal vesicle: 40.5 Cell line enhanced HEK 293: 7.4;HMC-1: 17.0;HSkMC: 6.1;U-266/84: 6.6 +CST7 ENSG00000077984 Cystatin F 20 24949230-24959928 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA040442 Enhanced Renal cancer:4.37e-6 (unfavourable), Endometrial cancer:9.17e-6 (favourable), Head and neck cancer:5.85e-5 (favourable), Breast cancer:6.55e-4 (favourable), Cervical cancer:7.90e-4 (favourable) Expressed in all Tissue enriched 9 bone marrow: 642.9 spleen: 74.1 Group enriched 19 HL-60: 58.5;HMC-1: 170.9;NB-4: 126.6;U-937: 278.1 +MAP2 MAP2A, MAP2B, MAP2C ENSG00000078018 Microtubule associated protein 2 2 209424058-209734118 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001984, HPA008273, HPA012828 Enhanced Supported Supported Nucleoli
Cytosol Endometrial cancer:1.98e-6 (unfavourable) Tissue enhanced Tissue enriched 11 cerebral cortex: 296.5 thyroid gland: 27.9 Cell line enhanced AF22: 293.3;NTERA-2: 106.5;SCLC-21H: 174.9;SH-SY5Y: 88.2 +PIAS2 miz, PIASX-ALPHA, PIASX-BETA, ZMIZ4 ENSG00000078043 Protein inhibitor of activated STAT 2 18 46803224-46920160 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA068792 Enhanced Supported Nucleoplasm Thyroid cancer:1.27e-4 (unfavourable) Expressed in all Group enriched 5 parathyroid gland: 28.5;testis: 119.6 cerebral cortex,thyroid gland: 13.8 Mixed +AMPH ENSG00000078053 Amphiphysin 7 38383704-38631567 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB008559, HPA019828, HPA019829 Enhanced Supported Plasma membrane
Cytosol Pancreatic cancer:9.96e-4 (favourable) Tissue enhanced Tissue enriched 9 cerebral cortex: 83.7 cervix, uterine: 8.9 Cell line enhanced ASC diff: 44.1;ASC TERT1: 26.4;BJ hTERT+ SV40 Large T+ RasG12V: 29.1;U-138 MG: 24.3 +ARAF ARAF1 ENSG00000078061 A-Raf proto-oncogene, serine/threonine kinase X 47561100-47571920 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046188, HPA066326 Approved Approved Nucleus
Nucleoli fibrillar center Renal cancer:1.45e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 86.3 Expressed in all +MCCC1 MCCA ENSG00000078070 Methylcrotonoyl-CoA carboxylase 1 3 183015218-183116075 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008310 Approved Enhanced Mitochondria Renal cancer:3.68e-4 (favourable) Expressed in all Expressed in all kidney: 57.9 Expressed in all +LAMP3 CD208, DC-LAMP, DCLAMP, LAMP, TSC403 ENSG00000078081 Lysosomal associated membrane protein 3 3 183122213-183163839 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025133, HPA051467 Enhanced Enhanced Vesicles Renal cancer:1.89e-7 (unfavourable), Ovarian cancer:9.90e-4 (favourable) Mixed Tissue enriched 7 lung: 319.3 appendix: 44.9 Group enriched 8 EFO-21: 154.0;HDLM-2: 40.5;HHSteC: 50.0;hTCEpi: 40.3 +FAP DPPIV ENSG00000078098 Fibroblast activation protein alpha 2 162170684-162245151 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059739 Approved Head and neck cancer:4.82e-4 (unfavourable) Mixed Tissue enhanced endometrium: 50.7 smooth muscle: 38.5 Cell line enhanced ASC diff: 128.1;ASC TERT1: 137.8;BJ hTERT+: 131.5;U-138 MG: 159.0 +NEBL LASP2, LNEBL ENSG00000078114 Nebulette 10 20779973-21174187 Predicted intracellular proteins Evidence at protein level HPA013994, HPA013995 Approved Renal cancer:2.77e-8 (favourable), Urothelial cancer:5.56e-4 (unfavourable) Mixed Tissue enhanced heart muscle: 200.0;thyroid gland: 125.4 cerebral cortex: 61.3 Cell line enhanced SCLC-21H: 69.4;SH-SY5Y: 37.8;SK-BR-3: 42.1 +ACER3 APHC, FLJ11238, PHCA ENSG00000078124 Alkaline ceramidase 3 11 76860867-77026797 Predicted membrane proteins Evidence at protein level HPA070087 Approved Liver cancer:2.49e-4 (unfavourable), Renal cancer:2.73e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 14.2 Mixed +UBE2K HIP2, HYPG, UBC1 ENSG00000078140 Ubiquitin conjugating enzyme E2 K 4 39698044-39782792 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028869, CAB033212, CAB033515 Supported Supported Intermediate filaments
Actin filaments
Cytosol Pancreatic cancer:8.60e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 64.7 Expressed in all +PIK3C3 Vps34 ENSG00000078142 Phosphatidylinositol 3-kinase catalytic subunit type 3 18 41955206-42087830 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040718 Approved Renal cancer:4.97e-4 (favourable) Expressed in all Expressed in all testis: 32.9 Expressed in all +N4BP2 B3BP ENSG00000078177 NEDD4 binding protein 2 4 40056826-40158252 Predicted intracellular proteins Evidence at protein level HPA036770, HPA042607 Approved Approved Nucleoplasm
Plasma membrane
Centrosome Expressed in all Mixed endometrium: 5.6 Cell line enhanced MOLT-4: 20.8 +TIGAR C12orf5 ENSG00000078237 TP53 induced glycolysis regulatory phosphatase 12 4307763-4354593 Enzymes, Predicted intracellular proteins Evidence at protein level CAB034010, HPA040354, HPA044111 Approved Enhanced Cytosol Liver cancer:3.18e-4 (unfavourable) Expressed in all Mixed smooth muscle: 9.9 Cell line enhanced BEWO: 81.8 +TULP3 TUBL3 ENSG00000078246 Tubby like protein 3 12 2877223-2941140 Predicted intracellular proteins Evidence at protein level HPA015285, HPA018496 Uncertain Supported Nucleus
Nucleoli
Plasma membrane Liver cancer:7.97e-5 (unfavourable), Endometrial cancer:2.99e-4 (favourable), Renal cancer:7.18e-4 (unfavourable) Expressed in all Expressed in all ovary: 46.5 Expressed in all +SYNJ2 INPP5H ENSG00000078269 Synaptojanin 2 6 157981887-158099176 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031575 Approved Approved Microtubules
Cytosol Renal cancer:4.02e-6 (unfavourable), Breast cancer:2.63e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 34.8 Mixed +ADCY2 AC2, HBAC2, KIAA1060 ENSG00000078295 Adenylate cyclase 2 5 7396208-7830081 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB031482, HPA038015, HPA038483 Approved Tissue enhanced Tissue enhanced cerebral cortex: 57.2;skeletal muscle: 23.6 prostate: 8.4 Group enriched 7 AF22: 5.6;NTERA-2: 4.3;SK-MEL-30: 3.8 +PPP2R5C B56G, PR61G ENSG00000078304 Protein phosphatase 2 regulatory subunit B'gamma 14 101761798-101927989 Predicted intracellular proteins Evidence at protein level HPA027553 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all Expressed in all lymph node: 157.9 Expressed in all +RBFOX1 A2BP1, FOX-1, HRNBP1 ENSG00000078328 RNA binding protein, fox-1 homolog 1 16 6019094-7713338 Predicted intracellular proteins Evidence at protein level HPA040809 Enhanced Approved Nucleus
Golgi apparatus
Cytosol Tissue enhanced Group enriched 5 cerebral cortex: 110.5;skeletal muscle: 32.9 heart muscle: 13.9 Cell line enriched 18 RH-30: 26.2 +GNB1 ENSG00000078369 G protein subunit beta 1 1 1785285-1891117 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA040736 Supported Approved Golgi apparatus
Plasma membrane Liver cancer:3.61e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 447.4 Expressed in all +HOXA9 HOX1, HOX1G ENSG00000078399 Homeobox A9 7 27162435-27175180 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA061982 Uncertain Supported Nucleus Mixed Mixed kidney: 12.6 Cell line enhanced HEK 293: 113.8;SCLC-21H: 133.7 +EDN1 ET1 ENSG00000078401 Endothelin 1 6 12290363-12297194 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA031976, CAB032500, CAB037291 Approved Approved Nucleus
Nucleoli
Golgi apparatus Expressed in all Mixed lung: 43.5 Group enriched 6 EFO-21: 622.7;HUVEC TERT2: 372.8;T-47d: 129.1;TIME: 272.4 +MLLT10 AF10 ENSG00000078403 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 10 21524675-21743630 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA005747 Supported Supported Nucleoplasm Head and neck cancer:8.75e-4 (favourable) Expressed in all Expressed in all testis: 177.6 Expressed in all +ZCWPW1 DKFZp434N0510, FLJ10057, ZCW1 ENSG00000078487 Zinc finger CW-type and PWWP domain containing 1 7 100400826-100428992 Predicted intracellular proteins Evidence at protein level HPA020911 Approved Golgi apparatus Pancreatic cancer:1.93e-4 (favourable), Cervical cancer:1.99e-4 (favourable), Lung cancer:4.84e-4 (favourable), Urothelial cancer:5.26e-4 (favourable) Expressed in all Tissue enriched 8 testis: 71.2 thyroid gland: 8.6 Mixed +ADCYAP1R1 PAC1, PAC1R, PACAPR ENSG00000078549 ADCYAP receptor type I 7 31052461-31111479 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA030739, HPA049877 Enhanced Supported Vesicles Endometrial cancer:5.78e-4 (favourable) Tissue enriched Tissue enhanced cerebral cortex: 137.1;fallopian tube: 46.8 cervix, uterine: 20.7 Group enriched 6 AF22: 3.6;NTERA-2: 4.9;SCLC-21H: 4.8;SH-SY5Y: 7.8 +FGF20 ENSG00000078579 Fibroblast growth factor 20 8 16992169-17002181 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Tissue enhanced Mixed cervix, uterine: 1.5 Cell line enhanced BJ hTERT+: 1.3;CAPAN-2: 4.6 +P2RY10 P2Y10 ENSG00000078589 Purinergic receptor P2Y10 X 78945332-78961954 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA036757, HPA065766 Enhanced Renal cancer:3.63e-4 (unfavourable) Mixed Tissue enhanced lymph node: 33.1;spleen: 22.6;tonsil: 24.0 appendix: 19.4 Group enriched 5 Karpas-707: 90.1;U-266/70: 20.1 +ITM2A BRICD2A, E25A ENSG00000078596 Integral membrane protein 2A X 79360384-79367667 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002918 Uncertain Nucleoplasm Liver cancer:3.66e-6 (favourable) Expressed in all Expressed in all ovary: 220.1 Cell line enriched 6 MOLT-4: 1365.5 +NRDC hNRD1, hNRD2, NRD1 ENSG00000078618 Nardilysin convertase 1 51789191-51878937 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053661 Approved Nucleoplasm Renal cancer:2.12e-9 (unfavourable), Liver cancer:5.49e-6 (unfavourable) Expressed in all Expressed in all testis: 167.5 Expressed in all +VDAC3 HD-VDAC3 ENSG00000078668 Voltage dependent anion channel 3 8 42391624-42405897 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026864 Uncertain Supported Mitochondria Expressed in all Expressed in all skeletal muscle: 327.2 Expressed in all +PCM1 PTC4 ENSG00000078674 Pericentriolar material 1 8 17922840-18029944 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023370, HPA023374, CAB058695 Enhanced Enhanced Nuclear membrane
Centrosome
Cytosol Expressed in all Expressed in all testis: 277.4 Expressed in all +TNRC6C FLJ20015, KIAA1582 ENSG00000078687 Trinucleotide repeat containing 6C 17 77959240-78108835 Predicted intracellular proteins Evidence at protein level HPA022007, HPA062051 Uncertain Approved Nucleus Pancreatic cancer:6.56e-5 (favourable) Expressed in all Mixed cerebral cortex: 18.4 Cell line enhanced MOLT-4: 27.6 +CBFA2T2 MTGR1, ZMYND3 ENSG00000078699 CBFA2/RUNX1 translocation partner 2 20 33490075-33650036 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA060523, HPA072433 Enhanced Approved Nuclear speckles Pancreatic cancer:6.93e-6 (favourable) Expressed in all Expressed in all prostate: 24.2 Expressed in all +BRINP1 DBC1, DBCCR1, FAM5A ENSG00000078725 BMP/retinoic acid inducible neural specific 1 9 119153458-119369467 Predicted secreted proteins, Transporters Evidence at protein level HPA038828 Approved Approved Microtubules Mixed Tissue enriched 8 cerebral cortex: 59.6 seminal vesicle: 7.2 Cell line enhanced HSkMC: 6.2;NTERA-2: 16.8;SCLC-21H: 8.7 +ITCH AIP4 ENSG00000078747 Itchy E3 ubiquitin protein ligase 20 34363235-34511393 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021126, HPA049032 Supported Supported Nucleoplasm Expressed in all Expressed in all testis: 73.2 Expressed in all +PKD2L2 TRPP5 ENSG00000078795 Polycystin 2 like 2, transient receptor potential cation channel 5 137887968-137942747 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level HPA041903, HPA043634 Approved Approved Plasma membrane
Cytosol Not detected Tissue enriched 12 testis: 14.9 adrenal gland,thyroid gland: 1.2 Mixed +TP53INP2 C20orf110, dJ1181N3.1, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, PINH ENSG00000078804 Tumor protein p53 inducible nuclear protein 2 20 34704290-34713439 Predicted intracellular proteins Evidence at protein level Renal cancer:1.26e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 86.9 Expressed in all +SDF4 Cab45 ENSG00000078808 Stromal cell derived factor 4 1 1216908-1232031 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA011249, CAB015227 Enhanced Enhanced Golgi apparatus Cervical cancer:5.89e-4 (unfavourable) Expressed in all Expressed in all small intestine: 128.7 Expressed in all +MYH7B dJ756N5.1, KIAA1512, MHC14, MYH14 ENSG00000078814 Myosin heavy chain 7B 20 34975403-35002437 Predicted intracellular proteins Evidence at protein level Urothelial cancer:8.44e-5 (favourable) Mixed Group enriched 11 heart muscle: 46.9;skeletal muscle: 55.9;testis: 11.7 cerebral cortex,prostate: 3.3 Cell line enhanced U-138 MG: 1.5 +BPIFB2 BPIL1, C20orf184, dJ726C3.2, LPLUNC2 ENSG00000078898 BPI fold containing family B member 2 20 33007600-33023709 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA049491, HPA060121 Enhanced Approved Vesicles Endometrial cancer:1.97e-5 (favourable) Group enriched Group enriched 23 esophagus: 98.5;salivary gland: 90.5 cervix, uterine: 4.0 Cell line enriched 418 Hep G2: 146.8 +TP73 P73 ENSG00000078900 Tumor protein p73 1 3652520-3736201 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002514, CAB003022, HPA027314, HPA044516 Enhanced Supported Nucleoplasm
Golgi apparatus Endometrial cancer:1.82e-4 (favourable), Cervical cancer:2.98e-4 (favourable), Head and neck cancer:9.50e-4 (favourable) Mixed Group enriched 5 fallopian tube: 10.8;skin: 7.7 prostate: 1.8 Cell line enhanced SCLC-21H: 21.2 +TOLLIP IL-1RAcPIP ENSG00000078902 Toll interacting protein 11 1274371-1309654 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038621, HPA038622 Enhanced Approved Plasma membrane
Cytosol Renal cancer:1.11e-16 (favourable), Glioma:4.57e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 132.3 Expressed in all +UBE2D4 HBUCE1 ENSG00000078967 Ubiquitin conjugating enzyme E2 D4 (putative) 7 43926438-43956136 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003920 Approved Approved Plasma membrane
Cytosol Pancreatic cancer:4.86e-4 (favourable), Prostate cancer:5.77e-4 (favourable), Renal cancer:6.51e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 12.5 Expressed in all +CLUL1 ENSG00000079101 Clusterin like 1 18 596988-650334 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025264, HPA075240 Supported Approved Endoplasmic reticulum
Plasma membrane Mixed Tissue enhanced prostate: 13.9 thyroid gland: 11.5 Cell line enhanced Hep G2: 23.4 +RUNX1T1 AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2 ENSG00000079102 RUNX1 translocation partner 1 8 91954967-92103286 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049852, HPA070951 Approved Supported Nucleoplasm Mixed Mixed cervix, uterine: 12.8 Cell line enhanced Daudi: 14.0;HEL: 32.2 +CDH17 cadherin, HPT-1 ENSG00000079112 Cadherin 17 8 94127171-94217303 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA023614, HPA023616, CAB025143, HPA026556 Enhanced Supported Cell Junctions Group enriched Group enriched 8 colon: 256.9;duodenum: 314.3;rectum: 267.3;small intestine: 294.3 appendix: 37.5 Group enriched 6 CACO-2: 81.5;U-266/70: 121.0 +THOC1 HPR1, P84 ENSG00000079134 THO complex 1 18 214520-268050 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019096, HPA019687 Enhanced Enhanced Nuclear speckles Renal cancer:1.80e-6 (unfavourable), Liver cancer:1.83e-5 (unfavourable), Ovarian cancer:2.89e-5 (favourable), Breast cancer:8.43e-4 (favourable), Urothelial cancer:9.62e-4 (favourable) Expressed in all Mixed testis: 29.3 Expressed in all +FKBP7 FKBP23 ENSG00000079150 FK506 binding protein 7 2 178463664-178478600 Enzymes, Predicted secreted proteins Evidence at protein level HPA008707 Approved Supported Supported Endoplasmic reticulum Renal cancer:4.61e-6 (unfavourable) Expressed in all Tissue enhanced ovary: 60.2 endometrium: 44.1 Cell line enhanced ASC diff: 104.3;ASC TERT1: 65.6 +OSBPL6 ORP6 ENSG00000079156 Oxysterol binding protein like 6 2 178194481-178402891 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA032131 Enhanced Approved Plasma membrane Mixed Tissue enhanced cerebral cortex: 15.5 skin: 9.2 Cell line enhanced HEL: 43.7 +SLC1A3 EA6, EAAT1, GLAST ENSG00000079215 Solute carrier family 1 member 3 5 36606355-36688334 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB002573, HPA037467, HPA037468 Enhanced Approved Nucleoli
Mitochondria Tissue enriched Tissue enriched 16 cerebral cortex: 518.2 adipose tissue: 31.9 Cell line enhanced AF22: 49.5;CACO-2: 68.8;HaCaT: 55.0 +XRCC5 KARP-1, KU80, Ku86, KUB2 ENSG00000079246 X-ray repair cross complementing 5 2 216107464-216206303 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004468, HPA025813, HPA064685 Supported Enhanced Nucleoplasm Liver cancer:2.10e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 213.3 Expressed in all +LXN ENSG00000079257 Latexin 3 158645822-158672693 Predicted intracellular proteins Evidence at protein level HPA014179, CAB025128 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.86e-5 (unfavourable) Expressed in all Expressed in all gallbladder: 60.9 Cell line enhanced HUVEC TERT2: 234.3;MCF7: 120.4 +SP140 LYSP100-A, LYSP100-B ENSG00000079263 SP140 nuclear body protein 2 230203110-230313215 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006162, HPA067493 Enhanced Approved Nucleoli fibrillar center
Mitochondria Mixed Group enriched 6 appendix: 32.8;lymph node: 64.4;spleen: 38.3;tonsil: 50.7 urinary bladder: 7.6 Cell line enhanced Daudi: 22.1;HDLM-2: 48.5;Karpas-707: 18.0;RPMI-8226: 11.2 +MKNK1 MNK1 ENSG00000079277 MAP kinase interacting serine/threonine kinase 1 1 46557408-46616843 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB027355, CAB037310, HPA071293 Approved Supported Nucleoplasm Liver cancer:1.24e-5 (unfavourable), Renal cancer:1.51e-5 (unfavourable), Cervical cancer:7.05e-4 (favourable) Expressed in all Expressed in all appendix: 35.8 Expressed in all +TNS1 DKFZp586K0617, MXRA6, PPP1R155, TNS ENSG00000079308 Tensin 1 2 217799789-218002995 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018774, HPA036089, HPA036090 Approved Enhanced Focal adhesion sites Colorectal cancer:2.41e-4 (unfavourable), Urothelial cancer:5.19e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 319.5 Cell line enhanced ASC diff: 102.7;fHDF/TERT166: 59.1;REH: 80.9 +REXO1 EloA-BP1, KIAA1138, TCEB3BP1 ENSG00000079313 RNA exonuclease 1 homolog 19 1815246-1848463 Predicted intracellular proteins Evidence at protein level HPA042155, HPA042552 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all testis: 35.1 Expressed in all +SAR1A SAR1, Sara, SARA1 ENSG00000079332 Secretion associated Ras related GTPase 1A 10 70147289-70170523 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006923, CAB022545, HPA048368 Supported Supported Endoplasmic reticulum Head and neck cancer:7.00e-5 (unfavourable), Liver cancer:4.04e-4 (unfavourable) Expressed in all Expressed in all placenta: 116.4 Expressed in all +CDC14A cdc14, Cdc14A1, Cdc14A2, DFNB105 ENSG00000079335 Cell division cycle 14A 1 100345025-100520277 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA023783 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Tissue enhanced testis: 56.3 fallopian tube: 19.8 Cell line enhanced K-562: 25.8 +RAPGEF3 bcm910, cAMP-GEFI, EPAC ENSG00000079337 Rap guanine nucleotide exchange factor 3 12 47734367-47771040 Predicted intracellular proteins Evidence at protein level CAB004386, HPA040365, HPA043518 Approved Approved Cytosol Renal cancer:6.67e-7 (favourable) Expressed in all Mixed thyroid gland: 43.0 Cell line enhanced EFO-21: 26.0 +CEACAM1 BGP, BGP1, CD66a ENSG00000079385 Carcinoembryonic antigen related cell adhesion molecule 1 19 42507304-42561234 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002146, HPA011041 Enhanced Endometrial cancer:6.32e-7 (favourable) Mixed Tissue enhanced colon: 202.3;rectum: 130.6 esophagus: 46.5 Cell line enhanced CAPAN-2: 25.2;Hep G2: 56.7;RT4: 43.1;SK-MEL-30: 47.4 +SENP1 ENSG00000079387 SUMO1/sentrin specific peptidase 1 12 48042898-48106308 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011765, HPA046491 Enhanced Nucleus
Focal adhesion sites Liver cancer:7.72e-5 (unfavourable), Renal cancer:8.37e-4 (unfavourable) Expressed in all Tissue enriched 8 testis: 110.1 lymph node: 13.3 Expressed in all +DUSP13 BEDP, DUSP13A, DUSP13B, FLJ32450, TMDP ENSG00000079393 Dual specificity phosphatase 13 10 75094432-75109221 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Mixed Group enriched 6 skeletal muscle: 84.9;testis: 47.5 heart muscle: 10.9 Cell line enhanced BEWO: 4.2;EFO-21: 4.7;Hep G2: 7.4;K-562: 3.8;LHCN-M2: 7.9;RH-30: 7.7 +CIC KIAA0306 ENSG00000079432 Capicua transcriptional repressor 19 42268537-42295797 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026388, HPA044341, HPA064725 Approved Supported Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 54.9 Expressed in all +LIPE HSL ENSG00000079435 Lipase E, hormone sensitive type 19 42401507-42427426 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006567, CAB017700 Enhanced Supported Cytosol Pancreatic cancer:1.15e-4 (favourable) Expressed in all Tissue enriched 20 adipose tissue: 870.5 testis: 44.0 Cell line enriched 6 ASC diff: 94.1 +FDFT1 ENSG00000079459 Farnesyl-diphosphate farnesyltransferase 1 8 11795573-11839309 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008874 Approved Supported Endoplasmic reticulum Renal cancer:6.59e-9 (favourable), Colorectal cancer:4.92e-5 (favourable) Expressed in all Expressed in all testis: 215.0 Expressed in all +PAFAH1B3 ENSG00000079462 Platelet activating factor acetylhydrolase 1b catalytic subunit 3 19 42297033-42303546 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035639 Uncertain Approved Intermediate filaments Renal cancer:2.07e-4 (unfavourable), Liver cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 36.7 Mixed +OPHN1 ARHGAP41, MRX60, OPN1 ENSG00000079482 Oligophrenin 1 X 68042344-68433913 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002919 Approved Approved Nucleus
Plasma membrane Mixed Mixed cerebral cortex: 20.1 Mixed +AFM ALB2, ALBA ENSG00000079557 Afamin 4 73481683-73504001 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA017006, HPA052437 Enhanced Liver cancer:1.80e-4 (favourable) Tissue enriched Tissue enriched 6 liver: 468.3 kidney: 80.9 Cell line enriched 6 CACO-2: 1.3 +KIF22 Kid, KNSL4, OBP-1, OBP-2 ENSG00000079616 Kinesin family member 22 16 29790719-29805385 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041076, HPA048213 Approved Approved Nuclear speckles Cervical cancer:3.87e-8 (favourable) Expressed in all Expressed in all bone marrow: 53.9 Expressed in all +SCGN CALBL, DJ501N12.8, SECRET, SEGN ENSG00000079689 Secretagogin, EF-hand calcium binding protein 6 25652201-25701783 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004005, HPA006641, CAB044060, CAB062563, CAB068232 Enhanced Supported Tissue enhanced Tissue enhanced rectum: 21.5;stomach: 20.6 colon: 17.0 Cell line enriched 6 SCLC-21H: 29.5 +CARMIL1 CARMIL, dJ501N12.1, FLJ20048, LRRC16, LRRC16A ENSG00000079691 Capping protein regulator and myosin 1 linker 1 6 25279078-25620530 Predicted intracellular proteins Evidence at protein level HPA029038, HPA029039 Enhanced Supported Cytosol Expressed in all Mixed testis: 22.2 Mixed +PGM1 ENSG00000079739 Phosphoglucomutase 1 1 63593276-63660245 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004666, HPA024190, HPA024637, HPA046329 Approved Enhanced Actin filaments Pancreatic cancer:8.74e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 512.9 Mixed +DDX1 DBP-RB ENSG00000079785 DEAD-box helicase 1 2 15591178-15631111 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012280, HPA034502, HPA034503 Enhanced Enhanced Nucleoplasm
Cytosol Liver cancer:9.09e-9 (unfavourable), Renal cancer:9.69e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 145.1 Expressed in all +DNM2 CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII ENSG00000079805 Dynamin 2 19 10718079-10833488 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA054246 Enhanced Approved Golgi apparatus
Cytosol Liver cancer:3.63e-4 (unfavourable), Head and neck cancer:8.91e-4 (favourable) Expressed in all Expressed in all colon: 103.9 Expressed in all +EPB41L2 4.1-G ENSG00000079819 Erythrocyte membrane protein band 4.1 like 2 6 130839347-131063322 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005730, HPA006642 Supported Enhanced Nucleus
Plasma membrane
Cell Junctions Liver cancer:2.41e-5 (unfavourable), Ovarian cancer:2.16e-4 (unfavourable) Expressed in all Expressed in all testis: 137.3 Mixed +RIMS1 CORD7, KIAA0340, RAB3IP2, RIM, RIM1 ENSG00000079841 Regulating synaptic membrane exocytosis 1 6 71886703-72403143 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 30.2 testis: 7.5 Cell line enhanced EFO-21: 8.3;LHCN-M2: 8.3;RPTEC TERT1: 11.5;SH-SY5Y: 11.4 +MOXD1 dJ248E1.1, DKFZP564G202, MOX ENSG00000079931 Monooxygenase DBH like 1 6 132296055-132401545 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035740 Approved Approved Nucleoplasm
Cytosol Head and neck cancer:7.09e-5 (favourable), Stomach cancer:3.72e-4 (unfavourable) Expressed in all Tissue enhanced endometrium: 106.1;smooth muscle: 114.5 seminal vesicle: 53.7 Cell line enhanced ASC diff: 111.5;fHDF/TERT166: 149.9;HBF TERT88: 116.1;U-2197: 280.6 +STX7 ENSG00000079950 Syntaxin 7 6 132445867-132513198 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001467, CAB062564 Enhanced Enhanced Lysosomes Liver cancer:1.60e-4 (unfavourable) Expressed in all Expressed in all lymph node: 91.4 Expressed in all +RABL2B ENSG00000079974 RAB, member of RAS oncogene family-like 2B 22 50767501-50783663 Predicted intracellular proteins Evidence at protein level HPA042642, HPA042700, HPA044007 Approved Approved Vesicles
Centrosome Liver cancer:4.58e-5 (unfavourable), Endometrial cancer:5.58e-4 (favourable) Expressed in all Expressed in all epididymis: 110.4 Expressed in all +KEAP1 INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454 ENSG00000079999 Kelch like ECH associated protein 1 19 10486120-10503741 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA005558, CAB025337 Approved Supported Nucleoplasm
Microtubule organizing center
Cytosol Cervical cancer:3.28e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 49.4 Expressed in all +DDX43 CT13, DKFZp434H2114, HAGE ENSG00000080007 DEAD-box helicase 43 6 73394748-73417569 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031381 Enhanced Tissue enriched Tissue enriched 5 testis: 34.6 placenta: 6.8 Cell line enhanced BEWO: 7.5;CAPAN-2: 11.7;HHSteC: 3.0;U-2 OS: 8.7 +PTPRH SAP-1 ENSG00000080031 Protein tyrosine phosphatase, receptor type H 19 55181248-55209506 Enzymes, Predicted membrane proteins Evidence at protein level HPA042300 Approved Mitochondria Mixed Tissue enhanced duodenum: 68.9;small intestine: 77.0 gallbladder: 38.6 Cell line enhanced HHSteC: 10.1;K-562: 13.5;SK-MEL-30: 17.2 +DCT TYRP2 ENSG00000080166 Dopachrome tautomerase 13 94436808-94479682 Enzymes, Predicted membrane proteins Evidence at protein level HPA010743, HPA010800, CAB017634 Enhanced Tissue enriched Tissue enriched 31 skin: 126.8 breast: 4.0 Cell line enriched 177 SK-MEL-30: 202.8 +SLC35C2 bA394O2.1, C20orf5, CGI-15, OVCOV1 ENSG00000080189 Solute carrier family 35 member C2 20 46345980-46364458 Predicted membrane proteins, Transporters Evidence at protein level HPA027011 Approved Supported Nucleoplasm
Golgi apparatus Liver cancer:1.08e-4 (unfavourable), Renal cancer:8.68e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 37.0 Expressed in all +CRYBG3 DKFZp667G2110 ENSG00000080200 Crystallin beta-gamma domain containing 3 3 97822040-97944963 Predicted intracellular proteins Evidence at protein level HPA044122 Approved Nucleoplasm
Cytosol Renal cancer:7.07e-4 (favourable) Mixed Tissue enhanced thyroid gland: 45.8 testis: 25.6 Cell line enhanced SCLC-21H: 47.0 +EPHA6 FLJ35246 ENSG00000080224 EPH receptor A6 3 96814581-97752460 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007397, HPA058047 Uncertain Enhanced Nucleoplasm Mixed Tissue enhanced ovary: 7.7;testis: 15.1 cerebral cortex: 3.6 Cell line enhanced HEK 293: 8.5;U-266/70: 21.4 +SCTR ENSG00000080293 Secretin receptor 2 119439843-119525301 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level HPA007269 Uncertain Tissue enhanced Tissue enhanced duodenum: 26.7;lung: 12.7;pancreas: 14.4 stomach: 4.1 Cell line enhanced Karpas-707: 2.2 +RFX3 ENSG00000080298 Regulatory factor X3 9 3218297-3526004 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035689 Enhanced Approved Nucleoplasm
Vesicles Breast cancer:1.47e-4 (favourable) Mixed Tissue enhanced testis: 38.6 fallopian tube: 18.3 Cell line enhanced AF22: 26.0;SCLC-21H: 16.6 +RIF1 FLJ10599, FLJ12870 ENSG00000080345 Replication timing regulatory factor 1 2 151409883-151508013 Predicted intracellular proteins Evidence at protein level HPA036887, HPA036888 Supported Uncertain Nucleus
Nuclear bodies
Plasma membrane Expressed in all Expressed in all testis: 21.1 Expressed in all +RAB21 KIAA0118 ENSG00000080371 RAB21, member RAS oncogene family 12 71754874-71800285 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016988, CAB037048 Approved Renal cancer:5.39e-8 (favourable) Expressed in all Mixed parathyroid gland: 12.2 Expressed in all +SLC4A4 hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5 ENSG00000080493 Solute carrier family 4 member 4 4 71186757-71572087 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB022493, HPA035628, HPA035629 Enhanced Renal cancer:1.18e-4 (favourable), Colorectal cancer:7.69e-4 (favourable) Group enriched Tissue enhanced kidney: 125.8 cerebral cortex: 59.3 Cell line enhanced BJ: 12.5;RPTEC TERT1: 11.7;U-138 MG: 8.0 +SMARCA2 BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2 ENSG00000080503 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 9 1980290-2193624 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029981, CAB037276 Enhanced Approved Nucleoplasm
Vesicles
Intermediate filaments Renal cancer:1.26e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 328.7 Cell line enriched 7 HDLM-2: 1364.0 +RDH8 PRRDH, SDR28C2 ENSG00000080511 Retinol dehydrogenase 8 (all-trans) 19 10013249-10022279 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Group enriched Group enriched 11 kidney: 1.2;testis: 1.8 appendix: 0.1 Not detected +SESN1 PA26, SEST1 ENSG00000080546 Sestrin 1 6 108986437-109094819 Enzymes, Predicted intracellular proteins Evidence at protein level HPA073659 Supported Nucleus
Nucleoli fibrillar center Head and neck cancer:6.47e-5 (favourable), Prostate cancer:2.07e-4 (favourable) Expressed in all Expressed in all testis: 78.9 Expressed in all +MID2 FXY2, MRX101, RNF60, TRIM1 ENSG00000080561 Midline 2 X 107825755-107927193 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Stomach cancer:3.73e-4 (unfavourable) Expressed in all Mixed smooth muscle: 23.4 Cell line enhanced HUVEC TERT2: 34.7;Karpas-707: 25.8 +PIH1D3 CXorf41, MGC35261, NYSAR97 ENSG00000080572 PIH1 domain containing 3 X 107206632-107244243 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA072496 Enhanced Tissue enhanced Group enriched 8 fallopian tube: 17.4;testis: 13.8 lung: 1.9 Not detected +COL5A3 ENSG00000080573 Collagen type V alpha 3 chain 19 9959561-10010471 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA048256 Approved Renal cancer:7.17e-8 (unfavourable), Urothelial cancer:6.87e-5 (unfavourable) Expressed in all Tissue enhanced placenta: 47.7 adipose tissue: 30.9 Cell line enhanced ASC TERT1: 27.4;BJ: 20.0;BJ hTERT+: 21.4;HSkMC: 20.6;WM-115: 25.9 +SRCAP DOMO1, EAF1, KIAA0309, SWR1 ENSG00000080603 Snf2 related CREBBP activator protein 16 30698209-30741409 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028929 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 55.6 Expressed in all +PUM3 HA-8, hPUF-A, KIAA0020, PEN, PUF6, XTP5 ENSG00000080608 Pumilio RNA binding family member 3 9 2720469-2844241 Predicted intracellular proteins Evidence at protein level HPA002353 Approved Supported Nucleoli Liver cancer:4.89e-5 (unfavourable), Prostate cancer:1.74e-4 (unfavourable) Expressed in all Expressed in all appendix: 28.4 Expressed in all +CPB2 CPU, PCPB, TAFI ENSG00000080618 Carboxypeptidase B2 13 46053186-46105076 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA004146 Approved Liver cancer:2.06e-4 (favourable) Tissue enriched Tissue enriched 28 liver: 755.5 lung: 26.5 Cell line enriched 66 Hep G2: 117.8 +CHRNA3 ENSG00000080644 Cholinergic receptor nicotinic alpha 3 subunit 15 78593052-78621295 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029430 Approved Mixed Tissue enriched 8 adrenal gland: 48.0 appendix: 6.3 Group enriched 25 SCLC-21H: 72.3;SH-SY5Y: 343.0 +KCNN2 hSK2, KCa2.2 ENSG00000080709 Potassium calcium-activated channel subfamily N member 2 5 114360945-114496500 Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA038221 Uncertain Uncertain Nucleoplasm
Cytosol Group enriched Tissue enhanced adrenal gland: 27.3 prostate: 15.9 Cell line enhanced BJ: 14.7;NTERA-2: 6.4;SK-MEL-30: 9.7;THP-1: 15.0;U-937: 6.2 +CNOT4 CLONE243, NOT4, NOT4H ENSG00000080802 CCR4-NOT transcription complex subunit 4 7 135361795-135510127 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005737 Approved Renal cancer:7.67e-6 (favourable), Liver cancer:1.19e-4 (unfavourable), Ovarian cancer:1.61e-4 (favourable) Expressed in all Expressed in all testis: 33.3 Expressed in all +PSEN1 AD3, FAD, PS1, S182 ENSG00000080815 Presenilin 1 14 73136418-73223691 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB006844, HPA030760, HPA067496 Approved Approved Nucleus
Golgi apparatus
Cell Junctions Renal cancer:1.52e-8 (favourable), Liver cancer:1.99e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 66.0 Expressed in all +CPOX CPO, CPX, HCP ENSG00000080819 Coproporphyrinogen oxidase 3 98521132-98593723 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA015736, HPA054448 Enhanced Mitochondria Renal cancer:1.04e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 25.5 Expressed in all +CLDND1 C3orf4 ENSG00000080822 Claudin domain containing 1 3 98497912-98523066 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA029841 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:5.84e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 399.9 Expressed in all +MOK RAGE, RAGE1, STK30 ENSG00000080823 MOK protein kinase 14 102224500-102305200 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027292 Supported Endoplasmic reticulum Mixed Tissue enhanced testis: 71.8 fallopian tube: 34.3 Cell line enhanced HBF TERT88: 143.8;hTEC/SVTERT24-B: 382.7;NB-4: 315.3;U-138 MG: 197.5 +HSP90AA1 FLJ31884, Hsp89, Hsp90, HSP90N, HSPC1, HSPCA ENSG00000080824 Heat shock protein 90 alpha family class A member 1 14 102080738-102139699 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002058 Approved Supported Cytosol Renal cancer:1.18e-5 (favourable), Liver cancer:3.09e-5 (unfavourable), Breast cancer:5.59e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1021.5 Expressed in all +RBL1 cp107, p107, PRB1 ENSG00000080839 RB transcriptional corepressor like 1 20 36996349-37095995 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054962, HPA056525 Enhanced Enhanced Nucleoplasm Renal cancer:2.52e-6 (unfavourable) Expressed in all Mixed bone marrow: 9.2 Expressed in all +DLGAP4 DAP4, KIAA0964, SAPAP4 ENSG00000080845 DLG associated protein 4 20 36306336-36528637 Predicted intracellular proteins Evidence at protein level HPA054105, HPA056378 Approved Approved Nucleoplasm
Focal adhesion sites
Cytosol Liver cancer:3.73e-6 (unfavourable), Endometrial cancer:2.24e-5 (unfavourable), Melanoma:9.88e-5 (favourable), Renal cancer:2.48e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 61.6 Expressed in all +IGSF9B KIAA1030 ENSG00000080854 Immunoglobulin superfamily member 9B 11 133908564-133956985 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA010744, HPA010802 Uncertain Approved Cytosol Mixed Mixed cerebral cortex: 9.0 Cell line enhanced SCLC-21H: 19.6;SH-SY5Y: 9.0 +CFHR2 CFHL2, FHR2, HFL3 ENSG00000080910 Complement factor H related 2 1 196943772-196959226 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA038915, HPA040726, HPA049813 Supported Tissue enriched Tissue enriched 4661 liver: 466.1 all non-specific tissues: 0.0 Not detected +NDC80 HEC, HEC1, hsNDC80, KNTC2, TID3 ENSG00000080986 NDC80, kinetochore complex component 18 2571511-2616635 Predicted intracellular proteins Evidence at protein level HPA066330 Supported Nucleoplasm
Centrosome Liver cancer:2.53e-8 (unfavourable) Expressed in all Mixed testis: 27.3 Expressed in all +AP4E1 AP-4-EPSILON, SPG51 ENSG00000081014 Adaptor related protein complex 4 epsilon 1 subunit 15 50908672-51005900 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041749, HPA041891 Approved Expressed in all Mixed parathyroid gland: 12.0 Expressed in all +RSBN1 FLJ11220, ROSBIN ENSG00000081019 Round spermatid basic protein 1 1 113761832-113812476 Predicted intracellular proteins Evidence at protein level HPA042124, HPA049484 Approved Supported Nucleoplasm
Nuclear bodies
Vesicles Expressed in all Expressed in all parathyroid gland: 22.0 Expressed in all +MAGI3 MAGI-3 ENSG00000081026 Membrane associated guanylate kinase, WW and PDZ domain containing 3 1 113390749-113685923 Predicted intracellular proteins Evidence at protein level HPA007923, HPA008444 Approved Supported Cell Junctions Renal cancer:2.60e-8 (favourable), Ovarian cancer:4.29e-4 (favourable) Expressed in all Mixed lung: 20.9 Mixed +CXCL2 CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, SCYB2 ENSG00000081041 C-X-C motif chemokine ligand 2 4 74097035-74099293 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:2.07e-6 (unfavourable), Breast cancer:5.93e-5 (favourable), Cervical cancer:1.41e-4 (unfavourable) Expressed in all Tissue enhanced liver: 110.2 lung: 95.2 Cell line enhanced BJ hTERT+: 38.3;HHSteC: 26.8;hTCEpi: 24.9;hTEC/SVTERT24-B: 24.7;hTERT-HME1: 25.6;U-87 MG: 27.5 +AFP FETA, HPAFP ENSG00000081051 Alpha fetoprotein 4 73431138-73456174 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA010607, HPA023600, CAB024283, CAB025339 Approved Uncertain Cytosol Group enriched Tissue enhanced liver: 1.9 breast: 0.5 Cell line enriched 158 Hep G2: 1466.5 +COL4A4 CA44 ENSG00000081052 Collagen type IV alpha 4 chain 2 227002711-227164113 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:2.30e-13 (favourable) Mixed Mixed thyroid gland: 14.1 Cell line enhanced HeLa: 16.3;RPTEC TERT1: 10.8 +TCF7 TCF-1 ENSG00000081059 Transcription factor 7 (T-cell specific, HMG-box) 5 134114711-134151865 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB019403, HPA058863, HPA070505 Enhanced Enhanced Nucleoplasm Expressed in all Tissue enhanced lymph node: 110.1 appendix: 71.7 Cell line enriched 13 MOLT-4: 1060.4 +OSTM1 GL, HSPC019 ENSG00000081087 Osteopetrosis associated transmembrane protein 1 6 108041409-108165854 Disease related genes, Predicted membrane proteins Evidence at protein level HPA010851 Uncertain Approved Nucleus
Vesicles
Cytosol Renal cancer:1.34e-6 (unfavourable), Stomach cancer:1.20e-4 (unfavourable), Liver cancer:4.26e-4 (unfavourable), Breast cancer:4.36e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 33.6 Expressed in all +CDH7 ENSG00000081138 Cadherin 7 18 65750252-65890341 Predicted membrane proteins Evidence at protein level HPA061419 Approved Tissue enhanced Tissue enhanced cerebral cortex: 2.8;prostate: 1.3 testis: 0.7 Cell line enhanced AF22: 15.0;Karpas-707: 4.0;RH-30: 7.0;U-87 MG: 3.3 +IMPG2 IPM200, RP56 ENSG00000081148 Interphotoreceptor matrix proteoglycan 2 3 101222546-101320560 Disease related genes, Predicted membrane proteins Evidence at protein level HPA008779, HPA015907 Supported Tissue enriched Tissue enriched 45 fallopian tube: 15.7 appendix,lymph node,spleen: 0.3 Not detected +PCNP ENSG00000081154 PEST proteolytic signal containing nuclear protein 3 101574095-101594437 Predicted intracellular proteins Evidence at protein level HPA035011 Supported Supported Nucleus Liver cancer:6.00e-5 (unfavourable) Expressed in all Expressed in all endometrium: 80.6 Expressed in all +EXD2 C14orf114, EXDL2, FLJ10738 ENSG00000081177 Exonuclease 3'-5' domain containing 2 14 69191511-69244020 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002906, HPA005848 Uncertain Approved Intermediate filaments
Mitochondria Renal cancer:2.08e-9 (favourable), Liver cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all testis: 36.6 Mixed +ARG2 ENSG00000081181 Arginase 2 14 67619798-67651720 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA000663, CAB009435 Enhanced Supported Mitochondria Expressed in all Tissue enhanced parathyroid gland: 94.0;prostate: 161.0;thyroid gland: 157.2 kidney: 63.4 Cell line enhanced HAP1: 54.8 +MEF2C ENSG00000081189 Myocyte enhancer factor 2C 5 88717117-88904257 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005533, CAB068196, CAB068197 Enhanced Supported Nucleoplasm
Vesicles Renal cancer:1.01e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 197.9 Cell line enhanced HEL: 205.2;REH: 238.4;WM-115: 143.4 +PTPRC CD45, GP180, LCA, T200 ENSG00000081237 Protein tyrosine phosphatase, receptor type C 1 198638671-198757283 Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000052, HPA000440, CAB002800, CAB056154, CAB068221 Enhanced Renal cancer:2.42e-4 (unfavourable) Expressed in all Expressed in all lymph node: 372.4 Cell line enhanced Daudi: 151.8;HEL: 73.7;HL-60: 73.8;MOLT-4: 105.0;U-698: 84.9;U-937: 62.5 +CACNA1S CACNL1A3, Cav1.1, HOKPP, hypoPP, MHS5 ENSG00000081248 Calcium voltage-gated channel subunit alpha1 S 1 201039512-201112566 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level CAB009507, HPA048892, HPA056815 Enhanced Tissue enhanced Tissue enriched 34 skeletal muscle: 103.0 esophagus: 3.0 Group enriched 20 BEWO: 2.0;HSkMC: 1.9 +PKP1 B6P ENSG00000081277 Plakophilin 1 1 201283452-201332993 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027221, HPA027589, CAB033130 Enhanced Enhanced Nucleoplasm Tissue enhanced Group enriched 11 esophagus: 281.6;skin: 821.6 prostate: 51.7 Cell line enhanced HaCaT: 205.1;HBEC3-KT: 102.1;hTCEpi: 358.4;hTERT-HME1: 100.7;PC-3: 176.6 +UBA5 FLJ23251, UBE1DC1 ENSG00000081307 Ubiquitin like modifier activating enzyme 5 3 132654446-132678097 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017235 Uncertain Enhanced Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 64.2 Expressed in all +STK17B DRAK2 ENSG00000081320 Serine/threonine kinase 17b 2 196133566-196176503 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034858 Enhanced Uncertain Plasma membrane
Cytosol Renal cancer:5.72e-8 (unfavourable) Expressed in all Tissue enhanced bone marrow: 248.5 lymph node: 133.3 Expressed in all +CDC14B Cdc14B1, Cdc14B2, CDC14B3, hCDC14B ENSG00000081377 Cell division cycle 14B 9 96490241-96619830 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013312, HPA064747 Approved Supported Nucleoplasm Renal cancer:2.97e-10 (favourable), Thyroid cancer:2.82e-4 (unfavourable) Expressed in all Mixed testis: 18.6 Cell line enhanced ASC TERT1: 21.4 +ZNF510 KIAA0972 ENSG00000081386 Zinc finger protein 510 9 96755865-96778129 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049139 Uncertain Approved Nucleoplasm
Plasma membrane Renal cancer:5.94e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 12.5 Expressed in all +LRP2 DBS, gp330 ENSG00000081479 LDL receptor related protein 2 2 169127109-169362685 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005980, HPA064792 Enhanced Approved Vesicles
Mitochondria Renal cancer:3.43e-5 (favourable) Group enriched Group enriched 6 kidney: 49.8;parathyroid gland: 155.8;thyroid gland: 37.0 breast: 14.2 Group enriched 11 AF22: 39.4;CACO-2: 56.2 +ZNF506 DKFZp761G1812 ENSG00000081665 Zinc finger protein 506 19 19785839-19821751 Predicted intracellular proteins, Transcription factors Evidence at transcript level Expressed in all Expressed in all thyroid gland: 16.2 Mixed +JMJD4 FLJ12517 ENSG00000081692 Jumonji domain containing 4 1 227730425-227735411 Predicted intracellular proteins Evidence at protein level HPA027260, HPA052861 Uncertain Approved Vesicles
Plasma membrane Renal cancer:3.16e-4 (unfavourable) Expressed in all Expressed in all testis: 12.9 Expressed in all +DUSP12 DUSP1, YVH1 ENSG00000081721 Dual specificity phosphatase 12 1 161749758-161757238 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008840 Uncertain Supported Nucleus Renal cancer:1.55e-7 (unfavourable), Liver cancer:1.99e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 20.3 Expressed in all +AACS ACSF1, FLJ12389, SUR-5 ENSG00000081760 Acetoacetyl-CoA synthetase 12 125065379-125143333 Enzymes, Predicted membrane proteins Evidence at protein level HPA058815 Approved Approved Vesicles Expressed in all Expressed in all breast: 55.0 Expressed in all +KIAA0141 DELE ENSG00000081791 KIAA0141 5 141923808-141942047 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036548, HPA061490 Uncertain Uncertain Nucleoplasm
Golgi apparatus Ovarian cancer:6.89e-4 (unfavourable) Expressed in all Expressed in all spleen: 62.3 Expressed in all +SLC13A1 NAS1, NaSi-1 ENSG00000081800 Solute carrier family 13 member 1 7 123113531-123199986 Predicted membrane proteins, Transporters Evidence at protein level HPA053615, HPA062714 Enhanced Renal cancer:8.95e-5 (favourable) Tissue enriched Tissue enriched 6 kidney: 85.0 small intestine: 14.1 Not detected +CADPS2 CAPS2 ENSG00000081803 Calcium dependent secretion activator 2 7 122318425-122886759 Predicted intracellular proteins Evidence at protein level HPA056398 Approved Nucleoplasm
Vesicles Renal cancer:1.01e-7 (favourable) Expressed in all Mixed parathyroid gland: 45.7 Cell line enhanced HUVEC TERT2: 36.2;Karpas-707: 40.4 +PCDHB4 PCDH-BETA4 ENSG00000081818 Protocadherin beta 4 5 141121799-141125623 Predicted membrane proteins Evidence at transcript level HPA014466 Approved Uncertain Plasma membrane
Intermediate filaments
Cytosol Mixed Mixed endometrium: 8.9 Group enriched 6 SCLC-21H: 10.2;SH-SY5Y: 6.2 +PCDHA6 CNR2, CNRS2, CRNR2, PCDH-ALPHA6 ENSG00000081842 Protocadherin alpha 6 5 140827958-141012344 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA059326, HPA078110 Enhanced Approved Vesicles Not detected Tissue enhanced cerebral cortex: 4.8 parathyroid gland: 1.9 Cell line enhanced AF22: 2.0;EFO-21: 8.1;U-2 OS: 3.7;WM-115: 5.1 +PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 Protocadherin gamma subfamily A, 2 5 141338760-141512979 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA008755, HPA010580, HPA038625 Approved Approved Nucleus
Nucleoli
Vesicles
Plasma membrane
Cytosol Mixed Mixed cerebral cortex: 8.4 Cell line enhanced ASC TERT1: 4.3;BJ: 3.0;fHDF/TERT166: 3.3 +HSPB11 C1orf41, HSPCO34, IFT25, PP25 ENSG00000081870 Heat shock protein family B (small) member 11 1 53916574-53945929 Predicted intracellular proteins Evidence at protein level HPA030140 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:9.58e-7 (unfavourable), Renal cancer:1.03e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 116.6 Expressed in all +PHLPP1 KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP ENSG00000081913 PH domain and leucine rich repeat protein phosphatase 1 18 62715450-62980433 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020200 Uncertain Renal cancer:5.35e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 40.9 Mixed +ATP8B1 ATPIC, BRIC, FIC1, PFIC, PFIC1 ENSG00000081923 ATPase phospholipid transporting 8B1 18 57646426-57803101 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018673, HPA018674 Enhanced Colorectal cancer:2.60e-4 (favourable), Renal cancer:6.35e-4 (favourable) Expressed in all Expressed in all colon: 94.6 Cell line enhanced RT4: 171.8 +IL12RB2 ENSG00000081985 Interleukin 12 receptor subunit beta 2 1 67307364-67396900 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA024168 Uncertain Uncertain Plasma membrane
Cytosol Tissue enhanced Tissue enhanced placenta: 11.8 cerebral cortex: 4.4 Cell line enhanced HMC-1: 4.6;SCLC-21H: 12.2;SK-MEL-30: 21.0;THP-1: 10.6 +SMARCD3 BAF60C, CRACD3, Rsc6p ENSG00000082014 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 7 151238764-151277896 Predicted intracellular proteins Evidence at protein level HPA063955, HPA065517 Uncertain Enhanced Nucleoplasm Colorectal cancer:5.50e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 82.7 Cell line enhanced AN3-CA: 63.9 +WDR70 FLJ10233 ENSG00000082068 WD repeat domain 70 5 37379212-37753435 Predicted intracellular proteins Evidence at protein level HPA043064, HPA048149 Uncertain Approved Mitochondria
Cytosol Melanoma:3.73e-4 (unfavourable), Endometrial cancer:4.34e-4 (unfavourable) Expressed in all Expressed in all endometrium: 18.1 Expressed in all +FYB FYB-120/130, SLAP-130 ENSG00000082074 FYN binding protein 5 39105236-39274528 Predicted intracellular proteins Evidence at protein level CAB025336, HPA026796 Enhanced Renal cancer:2.24e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 127.4;lymph node: 109.8;spleen: 114.9 tonsil: 64.3 Cell line enhanced HEL: 61.3;MOLT-4: 171.5;REH: 58.5;U-937: 68.8 +MPP4 DLG6 ENSG00000082126 Membrane palmitoylated protein 4 2 201644870-201698694 Predicted intracellular proteins Evidence at protein level HPA057393, CAB079019 Supported Supported Actin filaments
Cytosol Not detected Tissue enhanced skin: 1.0 testis: 0.9 Cell line enhanced HBF TERT88: 21.5;hTEC/SVTERT24-B: 21.1;LHCN-M2: 71.6;U-87 MG: 21.4 +STRADB ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK ENSG00000082146 STE20-related kinase adaptor beta 2 201387858-201480846 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026549, HPA028520 Approved Supported Aggresome
Cytosol Renal cancer:1.35e-4 (unfavourable), Thyroid cancer:4.45e-4 (favourable) Expressed in all Expressed in all kidney: 73.4 Cell line enhanced LHCN-M2: 154.7 +BZW1 BZAP45, KIAA0005 ENSG00000082153 Basic leucine zipper and W2 domains 1 2 200810594-200827338 Predicted intracellular proteins Evidence at protein level HPA047288, HPA053272 Uncertain Approved Vesicles Cervical cancer:4.28e-4 (unfavourable), Lung cancer:5.10e-4 (unfavourable) Expressed in all Expressed in all testis: 310.2 Expressed in all +PGR NR3C3, PR ENSG00000082175 Progesterone receptor 11 101029624-101130524 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000068, HPA004751, HPA008428, HPA017176, CAB055100 Enhanced Endometrial cancer:5.76e-8 (favourable) Group enriched Group enriched 6 cervix, uterine: 96.2;endometrium: 172.3;fallopian tube: 53.3;smooth muscle: 114.9 ovary: 19.5 Cell line enriched 349 T-47d: 157.7 +C1QTNF3 2310005P21Rik, Corcs, Cors, Cors-26, CTRP3 ENSG00000082196 C1q and tumor necrosis factor related protein 3 5 34019448-34043832 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA064996, HPA066011 Uncertain Approved Golgi apparatus Renal cancer:6.29e-4 (unfavourable) Expressed in all Tissue enhanced esophagus: 38.8 smooth muscle: 33.0 Cell line enriched 195 U-266/84: 563.8 +ME2 ENSG00000082212 Malic enzyme 2 18 50878734-50954257 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008247, HPA008880 Enhanced Enhanced Mitochondria Liver cancer:8.29e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 39.2 Expressed in all +C5orf22 FLJ11193 ENSG00000082213 Chromosome 5 open reading frame 22 5 31532266-31555058 Predicted intracellular proteins Evidence at protein level HPA043062 Approved Approved Nuclear membrane Liver cancer:6.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 14.5 Expressed in all +CCNT2 ENSG00000082258 Cyclin T2 2 134918235-134959342 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005559 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.25e-5 (unfavourable), Prostate cancer:2.44e-4 (unfavourable), Urothelial cancer:3.28e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 28.7 Expressed in all +FAM135A FLJ20176, KIAA1411 ENSG00000082269 Family with sequence similarity 135 member A 6 70412941-70561174 Predicted intracellular proteins Evidence at protein level HPA031743, HPA031744 Approved Approved Nucleoplasm
Cytosol Renal cancer:3.46e-4 (favourable), Colorectal cancer:8.00e-4 (favourable) Expressed in all Mixed esophagus: 33.3 Cell line enhanced RH-30: 29.8 +COL19A1 ENSG00000082293 Collagen type XIX alpha 1 chain 6 69866571-70209976 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042422 Uncertain Tissue enhanced Tissue enhanced lymph node: 3.2;tonsil: 2.9 spleen: 2.1 Cell line enhanced HDLM-2: 5.2;RH-30: 13.4;SCLC-21H: 4.6;SK-MEL-30: 9.3;WM-115: 9.7 +EPB41L3 4.1B, DAL1, KIAA0987 ENSG00000082397 Erythrocyte membrane protein band 4.1 like 3 18 5392381-5630700 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028605 Enhanced Enhanced Plasma membrane Mixed Expressed in all testis: 115.0 Cell line enhanced SCLC-21H: 77.1;TIME: 134.0 +COBLL1 KIAA0977 ENSG00000082438 Cordon-bleu WH2 repeat protein like 1 2 164653624-164843679 Predicted intracellular proteins Evidence at protein level HPA044933, HPA053344 Enhanced Approved Cell Junctions Renal cancer:5.27e-13 (favourable) Expressed in all Mixed placenta: 77.1 Mixed +DLG3 KIAA1232, MRX90, NE-Dlg, NEDLG, PPP1R82, SAP-102, SAP102 ENSG00000082458 Discs large MAGUK scaffold protein 3 X 70444861-70505490 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001733, HPA078130 Approved Approved Nucleus
Nucleoli Renal cancer:1.72e-10 (favourable), Breast cancer:1.69e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 36.6 Mixed +KCNK2 K2p2.1, TREK-1 ENSG00000082482 Potassium two pore domain channel subfamily K member 2 1 215005775-215237093 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Mixed Tissue enhanced adrenal gland: 75.2 thyroid gland: 17.0 Cell line enhanced ASC TERT1: 58.1;fHDF/TERT166: 59.9;T-47d: 108.4;U-2197: 38.1 +SERTAD4 DJ667H12.2 ENSG00000082497 SERTA domain containing 4 1 210232799-210246631 Predicted intracellular proteins Evidence at protein level HPA027344, HPA028514 Uncertain Supported Nucleoplasm Mixed Mixed breast: 4.6 Cell line enhanced SCLC-21H: 8.7;T-47d: 9.8;U-2 OS: 9.1 +TRAF5 RNF84 ENSG00000082512 TNF receptor associated factor 5 1 211326615-211374946 Predicted intracellular proteins Evidence at protein level HPA008052, CAB010277 Enhanced Supported Cytosol Renal cancer:2.94e-10 (unfavourable), Urothelial cancer:7.29e-5 (favourable) Expressed in all Mixed lymph node: 35.1 Cell line enhanced HDLM-2: 33.6 +MRPL22 HSPC158, MRP-L25, RPML25 ENSG00000082515 Mitochondrial ribosomal protein L22 5 154941070-154969411 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA047063 Uncertain Approved Mitochondria Expressed in all Expressed in all testis: 48.4 Expressed in all +GEMIN5 ENSG00000082516 Gem nuclear organelle associated protein 5 5 154887416-154938209 Predicted intracellular proteins Evidence at protein level HPA037392, HPA037393 Uncertain Enhanced Nuclear bodies
Cytosol Endometrial cancer:6.23e-5 (unfavourable), Liver cancer:1.78e-4 (unfavourable), Renal cancer:2.05e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 12.6 Expressed in all +OPRK1 KOR, OPRK ENSG00000082556 Opioid receptor kappa 1 8 53225716-53251697 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB022595, HPA067549 Uncertain Supported Nucleus
Plasma membrane
Cytosol Tissue enhanced Group enriched 7 cerebral cortex: 3.6;prostate: 2.8;testis: 1.3 placenta,skeletal muscle: 0.3 Group enriched 7 AF22: 4.5;U-937: 17.3 +NFE2L1 FLJ00380, LCR-F1, NRF1, TCF11 ENSG00000082641 Nuclear factor, erythroid 2 like 1 17 48048329-48061487 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA063384, HPA065424 Approved Approved Nucleus
Cytosol Renal cancer:5.79e-6 (favourable), Endometrial cancer:8.20e-5 (favourable), Head and neck cancer:2.73e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 468.1 Expressed in all +SEMA5B FLJ10372, KIAA1445, SEMAG, SemG ENSG00000082684 Semaphorin 5B 3 122909193-123028605 Predicted membrane proteins Evidence at protein level HPA066548 Enhanced Supported Cytosol Renal cancer:7.57e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 11.4 heart muscle: 4.2 Cell line enhanced AF22: 79.6;NTERA-2: 15.7;SH-SY5Y: 22.6 +GSK3B ENSG00000082701 Glycogen synthase kinase 3 beta 3 119821323-120094417 Enzymes, Predicted intracellular proteins Evidence at protein level CAB016263, HPA028017 Approved Enhanced Nucleus Liver cancer:8.20e-5 (unfavourable), Renal cancer:1.52e-4 (favourable) Expressed in all Expressed in all testis: 47.4 Expressed in all +ITGB5 ENSG00000082781 Integrin subunit beta 5 3 124761948-124901418 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001820, CAB022050 Approved Approved Plasma membrane
Mitochondria Pancreatic cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all placenta: 117.5 Cell line enhanced WM-115: 463.5 +ERC1 CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2 ENSG00000082805 ELKS/RAB6-interacting/CAST family member 1 12 990509-1495933 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019513, HPA019523, HPA024130 Approved Supported Vesicles
Plasma membrane
Cytosol Urothelial cancer:7.01e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 17.1 Expressed in all +XPO1 CRM1, emb ENSG00000082898 Exportin 1 2 61477849-61538626 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB010184, HPA042933 Supported Enhanced Nucleoplasm
Nuclear membrane
Vesicles
Cytosol Liver cancer:1.84e-5 (unfavourable), Renal cancer:3.74e-4 (unfavourable) Expressed in all Expressed in all testis: 139.1 Expressed in all +RNF13 RZF ENSG00000082996 Ring finger protein 13 3 149812708-149962139 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA064784 Approved Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:2.00e-8 (favourable) Expressed in all Expressed in all thyroid gland: 94.4 Expressed in all +TRPM3 GON-2, KIAA1616, LTRPC3 ENSG00000083067 Transient receptor potential cation channel subfamily M member 3 9 70529063-71446904 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Tissue enhanced Tissue enhanced kidney: 17.6 testis: 5.6 Cell line enriched 5 HAP1: 17.8 +PALB2 FANCN, FLJ21816 ENSG00000083093 Partner and localizer of BRCA2 16 23603160-23641310 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB014895, HPA057000 Approved Supported Nucleoplasm Pancreatic cancer:2.35e-5 (unfavourable), Colorectal cancer:2.83e-5 (favourable) Expressed in all Mixed testis: 14.5 Expressed in all +DOPEY1 dJ202D23.2, KIAA1117 ENSG00000083097 Dopey family member 1 6 83067666-83171350 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027902, HPA027904 Enhanced Approved Nucleus
Vesicles Pancreatic cancer:7.36e-4 (favourable) Expressed in all Mixed parathyroid gland: 25.5 Mixed +LYRM2 DJ122O8.2 ENSG00000083099 LYR motif containing 2 6 89568144-89638753 Predicted intracellular proteins Evidence at protein level HPA063932 Uncertain Approved Cytosol Liver cancer:2.58e-8 (unfavourable) Expressed in all Expressed in all thyroid gland: 42.3 Expressed in all +BCKDHB ENSG00000083123 Branched chain keto acid dehydrogenase E1 subunit beta 6 80106647-80346270 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA031580 Approved Renal cancer:5.54e-9 (favourable) Expressed in all Expressed in all liver: 39.9 Expressed in all +KAT6A MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220 ENSG00000083168 Lysine acetyltransferase 6A 8 41929479-42051990 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017023, HPA063266, HPA065052 Supported Approved Nucleoli
Nuclear speckles
Cytosol Expressed in all Expressed in all parathyroid gland: 34.5 Expressed in all +ZCCHC6 FLJ13409, KIAA1711, PAPD6, TUT7 ENSG00000083223 Zinc finger CCHC-type containing 6 9 86287733-86354454 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020615, HPA020620 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all prostate: 36.1 Expressed in all +ULK2 ATG1B, KIAA0623, Unc51.2 ENSG00000083290 Unc-51 like autophagy activating kinase 2 17 19770829-19867936 Enzymes, Predicted intracellular proteins Evidence at protein level HPA009027, CAB037021 Approved Expressed in all Expressed in all testis: 65.9 Mixed +GRHL2 BOM, DFNA28, FLJ13782, TFCP2L3 ENSG00000083307 Grainyhead like transcription factor 2 8 101492432-101669726 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004820, HPA062839 Uncertain Supported Nucleoplasm Pancreatic cancer:6.27e-4 (unfavourable), Breast cancer:6.43e-4 (unfavourable) Mixed Mixed prostate: 37.3 Cell line enhanced A-431: 34.0;HaCaT: 40.9;RT4: 54.7;T-47d: 74.7 +TNPO1 IPO2, KPNB2, MIP, MIP1, TRN ENSG00000083312 Transportin 1 5 72816312-72916733 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB016325 Approved Supported Nucleoplasm
Cytosol
Cytoplasmic bodies Liver cancer:6.55e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 110.4 Expressed in all +PLOD1 LH1, LLH, PLOD ENSG00000083444 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 1 11934205-11975538 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA049137, HPA055799 Uncertain Uncertain Nucleoplasm
Vesicles Renal cancer:1.91e-12 (unfavourable), Urothelial cancer:2.43e-4 (unfavourable), Liver cancer:2.79e-4 (unfavourable) Expressed in all Expressed in all placenta: 122.3 Expressed in all +P2RX5 LRH-1, P2X5 ENSG00000083454 Purinergic receptor P2X 5 17 3672199-3696404 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021948, HPA067827 Supported Supported Cytosol Mixed Group enriched 10 appendix: 40.9;lymph node: 89.8;spleen: 74.3;tonsil: 47.1 bone marrow: 6.2 Cell line enhanced Daudi: 36.5;RPMI-8226: 40.2;U-698: 32.6 +ITGAE CD103, HUMINAE ENSG00000083457 Integrin subunit alpha E 17 3714628-3801243 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB026461, HPA036313 Approved Renal cancer:1.13e-8 (unfavourable), Endometrial cancer:1.04e-4 (favourable), Urothelial cancer:3.56e-4 (favourable), Pancreatic cancer:5.78e-4 (favourable) Expressed in all Tissue enhanced lung: 9.5 small intestine: 6.2 Cell line enriched 22 MOLT-4: 9.6 +DIS3 dis3p, EXOSC11, KIAA1008, RRP44 ENSG00000083520 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease 13 72752169-72782096 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039281, HPA058762 Approved Enhanced Nucleus
Cytosol Expressed in all Expressed in all testis: 38.7 Expressed in all +PIBF1 C13orf24, CEP90 ENSG00000083535 Progesterone immunomodulatory binding factor 1 13 72782059-73016461 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052269, HPA066120 Approved Supported Microtubule organizing center Expressed in all Expressed in all testis: 25.9 Expressed in all +TDRD3 FLJ21007 ENSG00000083544 Tudor domain containing 3 13 60396457-60573878 Predicted intracellular proteins Evidence at protein level CAB034925, HPA067153 Approved Enhanced Nucleoplasm
Golgi apparatus
Cytosol Endometrial cancer:2.77e-4 (favourable) Expressed in all Expressed in all testis: 22.8 Expressed in all +NUFIP1 NUFIP ENSG00000083635 NUFIP1, FMR1 interacting protein 1 13 44939249-44989483 Predicted intracellular proteins Evidence at protein level HPA029958, HPA029959 Approved Enhanced Nucleus
Nucleoli Expressed in all Mixed testis: 10.2 Expressed in all +PDS5B APRIN, AS3, CG008, FLJ23236, KIAA0979 ENSG00000083642 PDS5 cohesin associated factor B 13 32586427-32778019 Predicted intracellular proteins Evidence at protein level HPA039513, HPA040015 Supported Enhanced Nucleoplasm Expressed in all Expressed in all endometrium: 31.3 Expressed in all +OXCT1 OXCT, SCOT ENSG00000083720 3-oxoacid CoA-transferase 1 5 41730065-41870519 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012047, HPA061425 Enhanced Enhanced Mitochondria Renal cancer:1.86e-8 (favourable), Liver cancer:1.03e-4 (unfavourable) Expressed in all Tissue enhanced heart muscle: 162.3 cerebral cortex: 98.7 Cell line enhanced SiHa: 338.4 +RRAGB ENSG00000083750 Ras related GTP binding B X 55717739-55758774 Predicted intracellular proteins Evidence at protein level HPA003734 Approved Approved Golgi apparatus
Vesicles Lung cancer:3.64e-6 (favourable), Glioma:5.36e-5 (favourable), Colorectal cancer:7.60e-4 (unfavourable) Expressed in all Expressed in all epididymis: 42.3 Expressed in all +EPYC DSPG3, Pg-Lb, SLRR3B ENSG00000083782 Epiphycan 12 90963679-91005026 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA038212, HPA045455 Approved Pancreatic cancer:1.85e-4 (unfavourable) Tissue enhanced Tissue enriched 6 placenta: 8.9 endometrium: 1.5 Not detected +CYLD CYLD1, KIAA0849, USPL2 ENSG00000083799 CYLD lysine 63 deubiquitinase 16 50742050-50801935 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB011713, HPA050095 Approved Supported Nucleoplasm
Microtubule organizing center Expressed in all Expressed in all testis: 70.2 Expressed in all +SLC27A5 ACSB, ACSVL6, FACVL3, FATP5, FLJ22987, VLACSR, VLCS-H2, VLCSH2 ENSG00000083807 Solute carrier family 27 member 5 19 58479512-58512413 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA007292, CAB056160, CAB068239 Enhanced Liver cancer:1.57e-4 (favourable) Tissue enriched Tissue enriched 23 liver: 337.5 fallopian tube: 14.7 Mixed +ZNF324 ZF5128, ZNF324A ENSG00000083812 Zinc finger protein 324 19 58467045-58475436 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA039774 Uncertain Approved Nucleus
Nuclear membrane
Cytosol Renal cancer:1.34e-7 (favourable), Pancreatic cancer:4.74e-5 (favourable), Thyroid cancer:6.99e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 8.6 Expressed in all +ZNF671 FLJ23506 ENSG00000083814 Zinc finger protein 671 19 57719751-57727624 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046099 Uncertain Approved Nucleoplasm Breast cancer:2.20e-4 (favourable), Pancreatic cancer:3.57e-4 (favourable) Mixed Mixed parathyroid gland: 16.6 Mixed +ZNF416 FLJ20557 ENSG00000083817 Zinc finger protein 416 19 57571566-57578927 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063318 Approved Nuclear bodies
Cytosol Renal cancer:1.20e-5 (favourable) Expressed in all Mixed testis: 7.8 Mixed +ZNF586 FLJ20070 ENSG00000083828 Zinc finger protein 586 19 57769655-57819939 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030306, HPA060782 Approved Approved Nucleoli fibrillar center
Vesicles Breast cancer:9.83e-5 (favourable), Urothelial cancer:5.36e-4 (favourable) Expressed in all Expressed in all bone marrow: 16.3 Mixed +ZNF446 FLJ20626, ZKSCAN20, ZSCAN52 ENSG00000083838 Zinc finger protein 446 19 58474017-58481230 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052786 Approved Nuclear speckles Pancreatic cancer:1.32e-4 (favourable) Expressed in all Mixed fallopian tube: 11.6 Expressed in all +ZNF264 KIAA0412 ENSG00000083844 Zinc finger protein 264 19 57191500-57222846 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057665 Uncertain Expressed in all Expressed in all testis: 18.3 Mixed +RPS5 S5 ENSG00000083845 Ribosomal protein S5 19 58386400-58394806 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055878, HPA061979 Enhanced Supported Endoplasmic reticulum
Cytosol Liver cancer:1.12e-5 (unfavourable), Renal cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all ovary: 2648.9 Expressed in all +FAT1 CDHF7, CDHR8, FAT ENSG00000083857 FAT atypical cadherin 1 4 186587783-186726722 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA001869, HPA023882 Approved Lung cancer:4.22e-4 (unfavourable) Expressed in all Mixed smooth muscle: 37.6 Cell line enhanced fHDF/TERT166: 221.3 +YTHDC1 KIAA1966, YT521, YT521-B ENSG00000083896 YTH domain containing 1 4 68310387-68350089 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036462 Supported Approved Nucleoplasm
Plasma membrane Urothelial cancer:7.29e-5 (favourable) Expressed in all Expressed in all bone marrow: 75.1 Expressed in all +CHMP2B CHMP2.5, DKFZP564O123, VPS2B ENSG00000083937 Charged multivesicular body protein 2B 3 87227271-87255548 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035069, HPA052754 Uncertain Supported Cytosol Renal cancer:1.74e-6 (favourable), Pancreatic cancer:2.11e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 78.5 Expressed in all +SMAP2 SMAP1L ENSG00000084070 Small ArfGAP2 1 40344850-40423326 Predicted intracellular proteins Evidence at protein level HPA021466, HPA024424 Approved Head and neck cancer:5.34e-5 (favourable), Liver cancer:2.53e-4 (unfavourable), Cervical cancer:6.55e-4 (favourable) Expressed in all Expressed in all lymph node: 232.8 Expressed in all +PPIE CyP-33, MGC111222, MGC3736 ENSG00000084072 Peptidylprolyl isomerase E 1 39692182-39763914 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019357, HPA020131 Approved Supported Nuclear speckles Renal cancer:5.05e-5 (unfavourable), Liver cancer:1.76e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 67.3 Expressed in all +ZMPSTE24 FACE-1, HGPS, PRO1, STE24, Ste24p ENSG00000084073 Zinc metallopeptidase STE24 1 40258107-40294184 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA006988 Approved Approved Golgi apparatus
Cytosol Liver cancer:5.73e-6 (unfavourable), Thyroid cancer:6.34e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 90.5 Expressed in all +STARD7 GTT1 ENSG00000084090 StAR related lipid transfer domain containing 7 2 96184859-96208825 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB033965, HPA064958, HPA064978 Supported Approved Mitochondria Renal cancer:4.38e-6 (favourable), Glioma:5.94e-6 (favourable), Endometrial cancer:8.56e-5 (unfavourable), Liver cancer:2.22e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 108.9 Expressed in all +NOA1 C4orf14, hAtNOS1, hNOA1, MGC3232, MTG3 ENSG00000084092 Nitric oxide associated 1 4 56963370-56978823 Predicted secreted proteins Evidence at protein level HPA035838, HPA035839 Approved Supported Mitochondria Renal cancer:2.38e-4 (favourable) Expressed in all Expressed in all fallopian tube: 16.9 Expressed in all +REST NRSF, XBR ENSG00000084093 RE1 silencing transcription factor 4 56907876-56966678 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006079, CAB068222 Supported Approved Nucleoplasm
Cytosol Renal cancer:9.50e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 32.2 Mixed +HAL HIS ENSG00000084110 Histidine ammonia-lyase 12 95972662-95996365 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038547, HPA038548 Enhanced Uncertain Cytosol Tissue enriched Group enriched 8 liver: 51.2;skin: 72.5 bone marrow: 7.4 Cell line enhanced BEWO: 2.1;THP-1: 7.4 +SSH1 KIAA1298 ENSG00000084112 Slingshot protein phosphatase 1 12 108778192-108857590 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019845 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Liver cancer:5.80e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 9.5 Expressed in all +GSTP1 FAEES3, GST3, GSTP ENSG00000084207 Glutathione S-transferase pi 1 11 67583595-67586660 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019779, HPA019869 Enhanced Supported Mitochondria
Cytosol Expressed in all Expressed in all esophagus: 1059.9 Expressed in all +APLP2 APPH, APPL2 ENSG00000084234 Amyloid beta precursor like protein 2 11 130069837-130144811 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA039319 Approved Approved Vesicles Renal cancer:1.33e-9 (favourable), Thyroid cancer:2.90e-4 (favourable), Liver cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 1056.8 Expressed in all +FAM234B KIAA1467 ENSG00000084444 Family with sequence similarity 234 member B 12 13044284-13142521 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010803, HPA010850 Approved Approved Endoplasmic reticulum Expressed in all Tissue enhanced cerebral cortex: 32.4 breast: 20.8 Expressed in all +SLCO1A2 OATP, OATP-A, OATP1A2, SLC21A3 ENSG00000084453 Solute carrier organic anion transporter family member 1A2 12 21264600-21419594 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA071152 Supported Plasma membrane Tissue enhanced Tissue enhanced cerebral cortex: 28.7 salivary gland: 6.6 Cell line enhanced NTERA-2: 16.5;RPMI-8226: 8.3;U-266/70: 18.6 +WBP11 NPWBP, PPP1R165, SIPP1 ENSG00000084463 WW domain binding protein 11 12 14784579-14803540 Predicted intracellular proteins Evidence at protein level HPA039710, HPA040037, HPA046403, HPA049126 Approved Enhanced Nucleoplasm Liver cancer:9.40e-4 (unfavourable) Expressed in all Expressed in all testis: 69.0 Expressed in all +EIF3I eIF3-beta, eIF3-p36, eIF3i, EIF3S2, TRIP-1 ENSG00000084623 Eukaryotic translation initiation factor 3 subunit I 1 32221928-32231604 Predicted intracellular proteins Evidence at protein level HPA029939, HPA029940 Enhanced Uncertain Nucleoplasm
Cytosol Renal cancer:4.81e-6 (unfavourable), Endometrial cancer:2.14e-4 (favourable), Liver cancer:4.21e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 198.1 Expressed in all +NKAIN1 FAM77C, FLJ12650 ENSG00000084628 Sodium/potassium transporting ATPase interacting 1 1 31179745-31239554 Predicted membrane proteins, Transporters Evidence at transcript level HPA006873 Uncertain Group enriched Group enriched 5 adrenal gland: 13.9;cerebral cortex: 13.1;epididymis: 4.4;skeletal muscle: 7.4 prostate: 1.9 Cell line enhanced AF22: 23.5;AN3-CA: 36.7;NTERA-2: 101.7;SCLC-21H: 35.5;SH-SY5Y: 50.9 +COL16A1 ENSG00000084636 Collagen type XVI alpha 1 chain 1 31652247-31704319 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027235, HPA027237 Approved Golgi apparatus
Plasma membrane
Cytosol Renal cancer:4.00e-9 (unfavourable), Glioma:7.08e-4 (unfavourable) Expressed in all Mixed ovary: 181.5 Cell line enhanced ASC diff: 88.5;BJ hTERT+: 91.9;fHDF/TERT166: 81.2;U-2197: 87.0 +TXLNA DKFZp451J0118 ENSG00000084652 Taxilin alpha 1 32179686-32198285 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA045383, HPA072477 Enhanced Approved Nucleoplasm
Centrosome
Cytosol Renal cancer:7.21e-7 (unfavourable), Liver cancer:1.57e-6 (unfavourable), Pancreatic cancer:8.69e-5 (favourable), Head and neck cancer:5.53e-4 (favourable), Breast cancer:6.24e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 48.1 Expressed in all +APOB ENSG00000084674 Apolipoprotein B 2 21001429-21044073 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB016070, HPA049793 Supported Supported Vesicles
Cytosol Tissue enriched Group enriched 120 duodenum: 182.8;liver: 618.9;small intestine: 333.2 adipose tissue: 3.1 Cell line enriched 25 Hep G2: 734.4 +NCOA1 bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1 ENSG00000084676 Nuclear receptor coactivator 1 2 24491914-24770702 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB019402, HPA070213, HPA070520 Enhanced Enhanced Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 59.0 Expressed in all +AGBL5 CCP5, FLJ21839 ENSG00000084693 ATP/GTP binding protein like 5 2 27042364-27070622 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA030981 Uncertain Supported Microtubules
Cytokinetic bridge
Cytosol Liver cancer:6.87e-5 (unfavourable) Expressed in all Tissue enriched 7 testis: 357.5 parathyroid gland: 50.4 Expressed in all +EFR3B FLJ37871, KIAA0953 ENSG00000084710 EFR3 homolog B 2 25042130-25159137 Predicted intracellular proteins Evidence at protein level HPA038089 Uncertain Mixed Tissue enhanced cerebral cortex: 33.2 skeletal muscle: 6.8 Cell line enhanced BEWO: 11.6;SH-SY5Y: 11.3;SK-BR-3: 13.6 +KIF3C ENSG00000084731 Kinesin family member 3C 2 25926596-25982749 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035755 Approved Nuclear membrane
Nuclear bodies
Intermediate filaments Endometrial cancer:1.32e-5 (unfavourable), Melanoma:1.22e-4 (favourable), Renal cancer:7.57e-4 (unfavourable) Expressed in all Tissue enriched 14 cerebral cortex: 129.6 adrenal gland: 9.1 Cell line enhanced SH-SY5Y: 57.6 +RAB10 ENSG00000084733 RAB10, member RAS oncogene family 2 26034107-26137454 Predicted intracellular proteins Evidence at protein level HPA045611 Approved Liver cancer:1.99e-5 (unfavourable), Pancreatic cancer:7.37e-5 (unfavourable), Endometrial cancer:7.40e-4 (unfavourable) Expressed in all Expressed in all esophagus: 185.7 Expressed in all +GCKR ENSG00000084734 Glucokinase regulator 2 27496842-27523684 Predicted intracellular proteins Evidence at protein level CAB034098, HPA064305 Enhanced Approved Intermediate filaments Tissue enriched Tissue enriched 7 liver: 44.3 stomach: 6.1 Group enriched 7 HEL: 12.0;Hep G2: 14.0;HUVEC TERT2: 5.3;TIME: 3.2 +HADHA GBP, LCEH, LCHAD, MTPA ENSG00000084754 Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 2 26190635-26244726 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015536, HPA056070 Approved Enhanced Mitochondria Renal cancer:3.68e-5 (favourable) Expressed in all Expressed in all duodenum: 235.3 Expressed in all +MAPRE3 EB3, RP3 ENSG00000084764 Microtubule associated protein RP/EB family member 3 2 26970612-27027196 Predicted intracellular proteins Evidence at protein level HPA009263 Uncertain Supported Cytosol Expressed in all Tissue enhanced cerebral cortex: 177.3 testis: 70.2 Mixed +CAD ENSG00000084774 Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 2 27217390-27243943 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB007781, HPA057266, HPA069341 Supported Supported Nucleoplasm Liver cancer:1.72e-11 (unfavourable), Renal cancer:1.82e-4 (unfavourable) Expressed in all Expressed in all skin: 22.0 Expressed in all +CD59 16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20 ENSG00000085063 CD59 molecule 11 33698261-33736445 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB001448, HPA026494 Supported Approved Golgi apparatus
Vesicles Renal cancer:1.39e-10 (favourable), Pancreatic cancer:2.92e-5 (unfavourable), Head and neck cancer:3.10e-5 (unfavourable), Cervical cancer:3.81e-5 (unfavourable), Stomach cancer:9.03e-4 (unfavourable) Expressed in all Expressed in all epididymis: 923.3 Cell line enhanced TIME: 2367.1;U-2197: 2401.2 +CD82 IA4, KAI1, R2, ST6, TSPAN27 ENSG00000085117 CD82 molecule 11 44564427-44620363 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002508, HPA028900, HPA061418 Supported Approved Vesicles Expressed in all Expressed in all esophagus: 131.5 Cell line enhanced HMC-1: 349.6;U-87 MG: 273.7 +BCORL1 CXorf10, FLJ11362 ENSG00000085185 BCL6 corepressor-like 1 X 129981107-130058083 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA031775, HPA031777, HPA068568 Uncertain Approved Nucleoplasm
Plasma membrane Endometrial cancer:2.20e-5 (unfavourable), Renal cancer:5.00e-4 (unfavourable) Expressed in all Expressed in all placenta: 18.3 Cell line enhanced HAP1: 51.8 +ATRX JMS, MRX52, RAD54, XH2, XNP ENSG00000085224 ATRX, chromatin remodeler X 77504878-77786269 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001906, CAB009372, HPA064684, CAB068176 Supported Supported Nuclear bodies Expressed in all Expressed in all parathyroid gland: 54.4 Expressed in all +AK6 CINAP ENSG00000085231 Adenylate kinase 6 5 69350984-69370013 Enzymes, Predicted intracellular proteins Evidence at protein level CAB005361, HPA034935 Supported Supported Nucleoplasm Liver cancer:9.54e-4 (unfavourable) Expressed in all Expressed in all epididymis: 26.8 Expressed in all +FCN1 FCNM ENSG00000085265 Ficolin 1 9 134905890-134917963 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA000685, HPA001295, CAB016760 Enhanced Renal cancer:3.98e-4 (unfavourable) Mixed Group enriched 5 appendix: 323.4;bone marrow: 634.5 spleen: 94.6 Group enriched 7 NB-4: 12.4;U-937: 22.6 +MYNN SBBIZ1, ZBTB31, ZNF902 ENSG00000085274 Myoneurin 3 169772831-169789716 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045149 Approved Supported Nucleus Expressed in all Expressed in all testis: 18.2 Expressed in all +MECOM EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3 ENSG00000085276 MDS1 and EVI1 complex locus 3 169083499-169663618 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046537 Supported Supported Nuclear speckles Pancreatic cancer:2.59e-4 (unfavourable) Mixed Mixed stomach: 67.3 Cell line enhanced HUVEC TERT2: 48.0;RPTEC TERT1: 55.1;RT4: 94.4;TIME: 45.0 +SCAMP1 SCAMP37 ENSG00000085365 Secretory carrier membrane protein 1 5 78360583-78479071 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044753, CAB079009 Approved Approved Nucleoplasm
Vesicles
Cell Junctions Renal cancer:1.92e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 69.2 Expressed in all +PREP ENSG00000085377 Prolyl endopeptidase 6 105277565-105403084 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB025414, HPA031388, HPA031389, HPA031390 Enhanced Enhanced Cytosol Head and neck cancer:3.33e-4 (unfavourable) Expressed in all Expressed in all rectum: 53.9 Expressed in all +HACE1 KIAA1320 ENSG00000085382 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 6 104728093-104859919 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046071 Supported Nuclear bodies
Endoplasmic reticulum Renal cancer:1.17e-5 (unfavourable), Thyroid cancer:7.50e-4 (unfavourable) Mixed Tissue enhanced placenta: 44.1 testis: 19.1 Mixed +SEH1L SEC13L, Seh1, SEH1A, SEH1B ENSG00000085415 SEH1 like nucleoporin 18 12947133-12987536 Predicted intracellular proteins, Transporters Evidence at protein level HPA039964 Uncertain Expressed in all Expressed in all cerebral cortex: 33.9 Expressed in all +WDR47 KIAA0893 ENSG00000085433 WD repeat domain 47 1 108970214-109042113 Predicted intracellular proteins Evidence at protein level HPA027287, HPA027289 Approved Approved Actin filaments Head and neck cancer:9.86e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 73.3 Expressed in all +WDFY1 FENS-1, KIAA1435, WDF1, ZFYVE17 ENSG00000085449 WD repeat and FYVE domain containing 1 2 223855716-223945387 Predicted intracellular proteins Evidence at protein level HPA050603 Approved Expressed in all Expressed in all placenta: 38.8 Expressed in all +OVGP1 CHIT5, MUC9 ENSG00000085465 Oviductal glycoprotein 1 1 111414314-111427777 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA062205 Enhanced Urothelial cancer:3.93e-5 (favourable), Endometrial cancer:1.36e-4 (favourable) Group enriched Tissue enriched 118 fallopian tube: 3146.3 endometrium: 26.7 Cell line enhanced HEK 293: 4.3 +SLC25A24 APC1, DKFZp586G0123 ENSG00000085491 Solute carrier family 25 member 24 1 108134036-108200849 Predicted intracellular proteins, Transporters Evidence at protein level HPA028519, HPA063636 Enhanced Enhanced Mitochondria Colorectal cancer:1.01e-4 (favourable) Expressed in all Mixed cervix, uterine: 22.1 Mixed +MAP3K4 KIAA0213, MAPKKK4, MEKK4, MTK1 ENSG00000085511 Mitogen-activated protein kinase kinase kinase 4 6 160991727-161117385 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA007625 Uncertain Approved Cytosol Expressed in all Expressed in all endometrium: 15.4 Expressed in all +PILRA FDF03 ENSG00000085514 Paired immunoglobin like type 2 receptor alpha 7 100367530-100400099 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA056132 Approved Renal cancer:1.61e-4 (unfavourable), Cervical cancer:2.99e-4 (favourable) Expressed in all Tissue enhanced appendix: 52.4 lung: 43.8 Cell line enhanced ASC diff: 18.7;HMC-1: 21.9;NB-4: 12.4 +IGSF9 IGSF9A, KIAA1355, Nrt1 ENSG00000085552 Immunoglobulin superfamily member 9 1 159927039-159945604 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA037753 Uncertain Endometrial cancer:5.16e-4 (unfavourable) Mixed Tissue enhanced skin: 28.1 stomach: 13.2 Cell line enhanced BEWO: 25.2;HaCaT: 34.4;SCLC-21H: 40.2 +ABCB1 ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1 ENSG00000085563 ATP binding cassette subfamily B member 1 7 87503633-87713323 Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB001716, HPA002199 Enhanced Approved Nucleoplasm
Focal adhesion sites
Cytosol Renal cancer:2.95e-4 (favourable), Pancreatic cancer:3.33e-4 (favourable) Tissue enhanced Tissue enhanced adrenal gland: 137.8;small intestine: 82.4 kidney: 37.3 Cell line enhanced CACO-2: 56.6;HEL: 34.4;SH-SY5Y: 85.9 +ZNF213 CR53, ZKSCAN21, ZSCAN53 ENSG00000085644 Zinc finger protein 213 16 3129777-3142805 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA035000, HPA056750 Uncertain Approved Nucleus
Nuclear membrane
Vesicles
Cytosol Liver cancer:6.74e-4 (unfavourable) Expressed in all Mixed testis: 16.3 Expressed in all +AKR1B1 ALDR1, AR ENSG00000085662 Aldo-keto reductase family 1 member B 7 134442350-134459284 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026425, CAB027391, CAB047353, HPA052751 Enhanced Supported Nucleus
Cytosol Stomach cancer:2.44e-5 (unfavourable), Urothelial cancer:7.00e-4 (unfavourable) Expressed in all Tissue enriched 6 adrenal gland: 2486.1 seminal vesicle: 449.2 Cell line enhanced A549: 1469.5;BJ hTERT+: 2394.4 +CPNE3 ENSG00000085719 Copine 3 8 86514427-86561498 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029552 Uncertain Supported Nucleus
Nucleoli
Mitochondria
Cytosol Renal cancer:5.07e-4 (favourable) Expressed in all Expressed in all thyroid gland: 103.4 Expressed in all +RRN3 DKFZp566E104, TIF-IA ENSG00000085721 RRN3 homolog, RNA polymerase I transcription factor 16 15060022-15094317 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049837 Supported Enhanced Nucleoli Expressed in all Expressed in all parathyroid gland: 22.3 Expressed in all +CTTN EMS1 ENSG00000085733 Cortactin 11 70398404-70436584 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011235, HPA057242 Supported Supported Golgi apparatus
Vesicles
Plasma membrane
Cytosol Head and neck cancer:2.19e-6 (unfavourable), Liver cancer:4.45e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 108.9 Cell line enhanced A-431: 778.5 +WNT11 ENSG00000085741 Wnt family member 11 11 76186325-76210736 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA050101, HPA063569 Uncertain Approved Centrosome
Cytosol Breast cancer:5.97e-4 (favourable) Mixed Tissue enhanced adipose tissue: 29.7;adrenal gland: 17.3 placenta: 5.7 Cell line enhanced BEWO: 34.3;CAPAN-2: 15.3;EFO-21: 53.0 +MTIF2 IF-2mt ENSG00000085760 Mitochondrial translational initiation factor 2 2 55236595-55269347 Predicted intracellular proteins Evidence at protein level HPA006021, HPA061422 Uncertain Enhanced Mitochondria Expressed in all Expressed in all parathyroid gland: 40.0 Expressed in all +DDHD2 KIAA0725, SAMWD1, SPG54 ENSG00000085788 DDHD domain containing 2 8 38225218-38275558 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015202, HPA023143, HPA023147 Supported Supported Microtubule organizing center
Cytosol Head and neck cancer:7.72e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 69.9 Expressed in all +TTC39A C1orf34, DEME-6, KIAA0452 ENSG00000085831 Tetratricopeptide repeat domain 39A 1 51287258-51345116 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028098, HPA043440 Uncertain Approved Centrosome Liver cancer:5.05e-5 (unfavourable) Mixed Tissue enhanced testis: 87.4 breast: 53.8 Cell line enhanced HDLM-2: 65.0;MCF7: 42.1;SK-BR-3: 123.3;T-47d: 112.3 +EPS15 AF-1P, MLLT5 ENSG00000085832 Epidermal growth factor receptor pathway substrate 15 1 51354263-51519328 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA008451, CAB010164, HPA061431 Approved Enhanced Vesicles
Cytosol Cervical cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all testis: 84.6 Expressed in all +ORC1 HSORC1, ORC1L, PARC1 ENSG00000085840 Origin recognition complex subunit 1 1 52372829-52404459 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027450 Approved Approved Nucleus
Plasma membrane
Cytosol Colorectal cancer:1.74e-5 (favourable), Liver cancer:3.22e-5 (unfavourable), Melanoma:3.69e-4 (unfavourable) Mixed Tissue enhanced bone marrow: 17.9 lymph node: 7.9 Mixed +MGST2 MGST-II ENSG00000085871 Microsomal glutathione S-transferase 2 4 139665768-139740745 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010707 Approved Approved Nucleoplasm Renal cancer:3.22e-9 (favourable), Endometrial cancer:5.26e-5 (favourable) Expressed in all Expressed in all liver: 178.3 Mixed +CHERP DAN16, ERPROT213-21 ENSG00000085872 Calcium homeostasis endoplasmic reticulum protein 19 16517889-16542530 Predicted intracellular proteins Evidence at protein level HPA050647 Uncertain Expressed in all Expressed in all cerebral cortex: 22.2 Expressed in all +ATG16L1 APG16L, ATG16A, ATG16L, FLJ10035, WDR30 ENSG00000085978 Autophagy related 16 like 1 2 233210051-233295674 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA012577, HPA063900 Enhanced Approved Cytosol Liver cancer:1.48e-5 (unfavourable), Renal cancer:1.70e-4 (unfavourable) Expressed in all Mixed testis: 12.8 Expressed in all +USP40 FLJ10785 ENSG00000085982 Ubiquitin specific peptidase 40 2 233475520-233566782 Enzymes, Predicted intracellular proteins Evidence at protein level HPA005821 Uncertain Approved Vesicles Expressed in all Expressed in all parathyroid gland: 31.5 Mixed +POMGNT1 FLJ20277, LGMD2O, MEB, MGAT1.2 ENSG00000085998 Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1 46188682-46220305 Disease related genes, Predicted membrane proteins Evidence at protein level HPA044518 Approved Liver cancer:3.52e-4 (unfavourable), Pancreatic cancer:4.27e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 123.1 Expressed in all +RAD54L hHR54, hRAD54, RAD54A ENSG00000085999 RAD54-like (S. cerevisiae) 1 46247688-46278473 Predicted intracellular proteins Evidence at protein level HPA028954, HPA051537 Approved Enhanced Nucleoplasm Cervical cancer:6.67e-4 (favourable) Mixed Tissue enhanced testis: 20.0 tonsil: 7.9 Mixed +MAST2 KIAA0807, MAST205 ENSG00000086015 Microtubule associated serine/threonine kinase 2 1 45786987-46036124 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level HPA039722, HPA040155 Approved Approved Cytosol Renal cancer:6.85e-13 (unfavourable), Liver cancer:4.31e-8 (unfavourable) Expressed in all Expressed in all testis: 78.6 Expressed in all +DNAJA1 dj-2, hdj-2, HSJ2, HSPF4, NEDD7 ENSG00000086061 DnaJ heat shock protein family (Hsp40) member A1 9 33025211-33039907 Predicted intracellular proteins Evidence at protein level HPA001306 Approved Supported Microtubules
Cytosol Renal cancer:3.40e-4 (favourable), Ovarian cancer:5.39e-4 (favourable) Expressed in all Expressed in all testis: 241.0 Expressed in all +B4GALT1 beta4Gal-T1, GGTB2 ENSG00000086062 Beta-1,4-galactosyltransferase 1 9 33104082-33167356 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA010806, HPA010807 Enhanced Enhanced Golgi apparatus Endometrial cancer:6.85e-7 (favourable), Lung cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 140.5 Expressed in all +CHMP5 C9orf83, CGI-34, HSPC177, SNF7DC2, Vps60 ENSG00000086065 Charged multivesicular body protein 5 9 33264879-33282069 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033874, HPA042883, HPA056437 Enhanced Supported Microtubules
Midbody
Cytosol Renal cancer:2.87e-7 (favourable) Expressed in all Expressed in all thyroid gland: 127.5 Expressed in all +NFX1 MGC20369, NFX2, TEG-42, Tex42 ENSG00000086102 Nuclear transcription factor, X-box binding 1 9 33290511-33371157 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056310, HPA061382, HPA073519 Approved Enhanced Nucleus
Cytosol Ovarian cancer:3.75e-4 (favourable) Expressed in all Expressed in all thyroid gland: 38.8 Expressed in all +AQP6 AQP2L ENSG00000086159 Aquaporin 6 12 49967194-49977139 Predicted membrane proteins, Transporters Evidence at protein level HPA015278 Enhanced Tissue enriched Tissue enriched 9 kidney: 20.8 cerebral cortex: 2.3 Not detected +DIMT1 DIMT1L, HSA9761 ENSG00000086189 DIM1 dimethyladenosine transferase 1 homolog 5 62387254-62403939 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042944 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:8.90e-12 (unfavourable), Liver cancer:6.93e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 33.7 Expressed in all +IPO11 RanBP11 ENSG00000086200 Importin 11 5 62403972-62628582 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA067097 Approved Enhanced Nucleus
Nucleoli fibrillar center Liver cancer:4.28e-5 (unfavourable), Colorectal cancer:1.70e-4 (favourable) Expressed in all Expressed in all testis: 40.6 Expressed in all +FOLH1 FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA ENSG00000086205 Folate hydrolase 1 11 49146635-49208670 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB001451, HPA010593 Enhanced Renal cancer:1.30e-6 (unfavourable), Endometrial cancer:5.24e-5 (favourable), Liver cancer:4.25e-4 (favourable) Tissue enriched Group enriched 6 duodenum: 298.8;prostate: 136.6;small intestine: 90.8 cerebral cortex: 31.0 Mixed +EIF2AK1 HRI, KIAA1369 ENSG00000086232 Eukaryotic translation initiation factor 2 alpha kinase 1 7 6022244-6059230 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA016496, CAB022082, HPA061675 Approved Supported Nucleus
Cytosol Liver cancer:6.99e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 129.4 Expressed in all +NME8 CILD6, NM23-H8, SPTRX2, TXNDC3 ENSG00000086288 NME/NM23 family member 8 7 37848597-37900401 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016416, HPA019259 Supported Mixed Group enriched 14 bone marrow: 8.2;testis: 18.4 appendix,spleen: 0.9 Cell line enhanced HMC-1: 1.1;NB-4: 1.2;NTERA-2: 1.7;THP-1: 1.1;U-937: 4.1 +EPDR1 EPDR, MERP-1, MERP1, UCC1 ENSG00000086289 Ependymin related 1 7 37683843-37951941 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026298 Approved Urothelial cancer:1.00e-4 (unfavourable), Stomach cancer:3.43e-4 (unfavourable), Liver cancer:6.97e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 73.4 Cell line enhanced WM-115: 112.2 +SNX10 ENSG00000086300 Sorting nexin 10 7 26291895-26374329 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA015605, HPA064782 Approved Approved Nucleus
Nucleoli
Microtubules Renal cancer:8.06e-5 (unfavourable), Glioma:9.81e-5 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 94.3 lung: 60.1 Cell line enhanced WM-115: 291.7 +SEPHS1 SPS, SPS1 ENSG00000086475 Selenophosphate synthetase 1 10 13317424-13348298 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037645, HPA062118 Enhanced Uncertain Nucleoplasm Liver cancer:2.16e-7 (unfavourable), Pancreatic cancer:3.12e-4 (favourable) Expressed in all Expressed in all thyroid gland: 92.9 Expressed in all +MRPL28 MAAT1, p15 ENSG00000086504 Mitochondrial ribosomal protein L28 16 367384-370527 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA030594, CAB033542, HPA055589 Enhanced Supported Mitochondria Expressed in all Expressed in all cerebral cortex: 71.5 Expressed in all +HBQ1 HBQ ENSG00000086506 Hemoglobin subunit theta 1 16 180453-181181 Predicted intracellular proteins Evidence at protein level HPA062473 Enhanced Approved Lipid droplets Mixed Group enriched 8 bone marrow: 14.7;cerebral cortex: 3.0 placenta: 1.1 Group enriched 7 HEL: 19.6;Hep G2: 10.4;K-562: 49.1 +ITPKC IP3-3KC, IP3KC ENSG00000086544 Inositol-trisphosphate 3-kinase C 19 40717103-40740860 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA050760, HPA053003 Approved Supported Nuclear speckles Lung cancer:4.91e-4 (unfavourable) Expressed in all Expressed in all esophagus: 69.3 Mixed +CEACAM6 CD66c, NCA ENSG00000086548 Carcinoembryonic antigen related cell adhesion molecule 6 19 41750977-41772208 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB008370, HPA011041 Enhanced Mixed Group enriched 6 bone marrow: 110.7;colon: 180.6;esophagus: 173.5;gallbladder: 189.0;lung: 405.6;rectum: 233.8 appendix: 37.6 Cell line enriched 9 A549: 140.1 +FAT2 CDHF8, CDHR9, HFAT2, MEGF1 ENSG00000086570 FAT atypical cadherin 2 5 151504093-151568944 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB033680 Enhanced Group enriched Tissue enhanced skin: 66.5 esophagus: 14.3 Group enriched 9 BEWO: 33.8;EFO-21: 19.8;HaCaT: 45.7;HBEC3-KT: 16.9;hTCEpi: 51.0 +RBM22 Cwc2, FLJ10290, fSAP47, ZC3H16 ENSG00000086589 RNA binding motif protein 22 5 150690794-150701107 Predicted intracellular proteins Evidence at protein level HPA001634 Supported Enhanced Nucleus Liver cancer:5.50e-6 (unfavourable), Renal cancer:3.58e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 40.5 Expressed in all +TMED2 P24A, p24b1, p24beta1, RNP24 ENSG00000086598 Transmembrane p24 trafficking protein 2 12 123584531-123598577 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA014060 Approved Supported Vesicles Renal cancer:2.35e-7 (unfavourable), Head and neck cancer:3.36e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 328.1 Expressed in all +ERO1B ERO1-L(beta), Ero1beta, ERO1LB ENSG00000086619 Endoplasmic reticulum oxidoreductase 1 beta 1 236215555-236281985 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028085 Approved Lung cancer:7.53e-5 (favourable) Expressed in all Expressed in all testis: 51.5 Mixed +ZFAND6 AWP1, ZA20D3, ZFAND5B ENSG00000086666 Zinc finger AN1-type containing 6 15 80059568-80138393 Predicted intracellular proteins Evidence at protein level HPA034845 Uncertain Urothelial cancer:8.20e-4 (favourable) Expressed in all Expressed in all testis: 247.8 Expressed in all +HSD17B2 HSD17, SDR9C2 ENSG00000086696 Hydroxysteroid 17-beta dehydrogenase 2 16 82035004-82098534 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021826, HPA050235 Enhanced Approved Endoplasmic reticulum Urothelial cancer:3.83e-4 (favourable) Tissue enhanced Tissue enhanced duodenum: 430.9;placenta: 552.6 small intestine: 199.4 Cell line enhanced BJ hTERT+: 47.0;Hep G2: 32.2;RT4: 77.0;TIME: 44.0 +TXLNG CXorf15, FIAT, FLJ11209, LSR5, MGC126621, MGC126625, TXLNGX ENSG00000086712 Taxilin gamma X 16786427-16844519 Predicted intracellular proteins Evidence at protein level HPA000297, HPA000841 Enhanced Approved Cytosol Liver cancer:6.33e-6 (unfavourable) Expressed in all Expressed in all adrenal gland: 20.8 Expressed in all +PPEF1 PPEF, PPP7CA ENSG00000086717 Protein phosphatase with EF-hand domain 1 X 18675909-18827921 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034577 Uncertain Uncertain Plasma membrane
Cytokinetic bridge Mixed Tissue enriched 7 testis: 26.4 cerebral cortex: 3.6 Cell line enhanced A549: 1.0;HeLa: 1.1 +LAT2 HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5 ENSG00000086730 Linker for activation of T-cells family member 2 7 74199652-74229834 Disease related genes, Predicted secreted proteins Evidence at protein level HPA003462 Enhanced Renal cancer:4.10e-4 (unfavourable), Testis cancer:6.10e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 70.0 tonsil: 58.3 Cell line enhanced NB-4: 128.3;REH: 209.9;THP-1: 139.1;U-937: 157.8 +HUWE1 Ib772, KIAA0312, UREB1 ENSG00000086758 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase X 53532096-53686729 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002548, CAB022718 Approved Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 96.6 Expressed in all +ZW10 KNTC1AP ENSG00000086827 Zw10 kinetochore protein 11 113733187-113773811 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011565, HPA051253, HPA055410 Enhanced Supported Endoplasmic reticulum
Cytosol Colorectal cancer:2.70e-4 (favourable), Liver cancer:8.57e-4 (unfavourable) Expressed in all Expressed in all testis: 23.4 Expressed in all +ALG9 DIBD1 ENSG00000086848 ALG9, alpha-1,2-mannosyltransferase 11 111782195-111871581 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA038575 Approved Approved Endoplasmic reticulum Renal cancer:7.29e-5 (unfavourable) Expressed in all Expressed in all testis: 25.8 Expressed in all +MYBPC2 MGC163408, MYBPC, MYBPCF ENSG00000086967 Myosin binding protein C, fast type 19 50432903-50466321 Predicted intracellular proteins Evidence at protein level HPA042991, HPA046745 Enhanced Tissue enriched Group enriched 124 parathyroid gland: 934.4;skeletal muscle: 1495.9 prostate: 9.7 Group enriched 19 HDLM-2: 54.5;Karpas-707: 102.8 +NOX4 KOX, KOX-1 ENSG00000086991 NADPH oxidase 4 11 89324356-89498187 Predicted membrane proteins, Transporters Evidence at protein level HPA015475 Approved Nucleus Renal cancer:6.14e-4 (favourable) Mixed Tissue enriched 12 kidney: 134.7 parathyroid gland: 10.9 Group enriched 6 HUVEC TERT2: 22.0;TIME: 48.5 +ACOX3 ENSG00000087008 Acyl-CoA oxidase 3, pristanoyl 4 8366282-8440723 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035840, HPA035841 Uncertain Approved Peroxisomes Endometrial cancer:2.16e-4 (favourable) Expressed in all Expressed in all esophagus: 22.2 Expressed in all +MTMR2 CMT4B, KIAA1073 ENSG00000087053 Myotubularin related protein 2 11 95832882-95925315 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA049831 Approved Supported Vesicles Liver cancer:1.61e-8 (unfavourable), Pancreatic cancer:3.60e-4 (unfavourable) Expressed in all Expressed in all testis: 57.8 Expressed in all +PPP1R15A GADD34 ENSG00000087074 Protein phosphatase 1 regulatory subunit 15A 19 48872392-48876057 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB018395, HPA020240 Approved Uncertain Vesicles Liver cancer:1.95e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 358.1 Expressed in all +HSD17B14 DHRS10, retSDR3, SDR47C1 ENSG00000087076 Hydroxysteroid 17-beta dehydrogenase 14 19 48813017-48836678 Predicted intracellular proteins Evidence at protein level HPA021467 Approved Pancreatic cancer:2.87e-5 (favourable), Colorectal cancer:4.39e-5 (unfavourable) Expressed in all Mixed kidney: 53.3 Cell line enhanced HHSteC: 35.4;Karpas-707: 35.4;RT4: 28.6 +TRIP6 MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1 ENSG00000087077 Thyroid hormone receptor interactor 6 7 100867138-100873454 Predicted intracellular proteins Evidence at protein level CAB046454, CAB046460, HPA052813 Approved Supported Plasma membrane
Focal adhesion sites
Cytosol Expressed in all Expressed in all parathyroid gland: 84.7 Mixed +ACHE YT ENSG00000087085 Acetylcholinesterase (Cartwright blood group) 7 100889994-100896974 Blood group antigen proteins, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA019704, HPA027098 Approved Golgi apparatus
Vesicles Renal cancer:3.88e-5 (unfavourable), Glioma:7.16e-4 (unfavourable) Mixed Tissue enhanced skeletal muscle: 58.5 cerebral cortex: 14.1 Cell line enhanced BEWO: 11.7;CACO-2: 17.5;K-562: 20.7;Karpas-707: 25.8 +FTL MGC71996, NBIA3 ENSG00000087086 Ferritin light chain 19 48965301-48966878 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB020769, HPA041602 Enhanced Approved Cytosol Renal cancer:4.40e-5 (unfavourable) Expressed in all Expressed in all lung: 8050.1 Expressed in all +SRRT ARS2, Asr2, serrate ENSG00000087087 Serrate, RNA effector molecule 7 100875111-100888664 Predicted intracellular proteins Evidence at protein level HPA042858, HPA058379 Supported Enhanced Nucleoplasm Renal cancer:1.01e-6 (unfavourable), Liver cancer:1.90e-5 (unfavourable) Expressed in all Expressed in all testis: 203.6 Expressed in all +BAX BCL2L4 ENSG00000087088 BCL2 associated X, apoptosis regulator 19 48954815-48961798 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level CAB004206, HPA027878 Approved Liver cancer:1.63e-5 (unfavourable) Expressed in all Expressed in all appendix: 80.3 Expressed in all +NLK ENSG00000087095 Nemo like kinase 17 28041737-28196381 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018192, HPA056511 Approved Supported Nucleus
Nucleoli
Cell Junctions Expressed in all Expressed in all cerebral cortex: 52.4 Expressed in all +PIGS ENSG00000087111 Phosphatidylinositol glycan anchor biosynthesis class S 17 28553383-28571872 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA018149 Approved Liver cancer:1.86e-4 (unfavourable), Urothelial cancer:5.31e-4 (unfavourable) Expressed in all Mixed thyroid gland: 13.5 Expressed in all +ADAMTS2 ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP ENSG00000087116 ADAM metallopeptidase with thrombospondin type 1 motif 2 5 179110851-179345430 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028444 Uncertain Approved Vesicles
Plasma membrane Renal cancer:1.71e-8 (unfavourable) Expressed in all Mixed placenta: 14.7 Cell line enhanced HHSteC: 100.5;HSkMC: 69.6 +TMPRSS11E DESC1, TMPRSS11E2 ENSG00000087128 Transmembrane protease, serine 11E 4 68447449-68497604 Enzymes, Predicted membrane proteins Evidence at protein level HPA051062 Uncertain Lung cancer:6.73e-4 (unfavourable) Group enriched Tissue enriched 5 esophagus: 128.2 epididymis: 25.0 Cell line enhanced HaCaT: 1.4 +ATXN7L3 DKFZp761G2113 ENSG00000087152 Ataxin 7 like 3 17 44191805-44200113 Predicted intracellular proteins Evidence at protein level HPA064316 Supported Approved Nuclear speckles
Plasma membrane Renal cancer:2.87e-4 (unfavourable), Liver cancer:4.03e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 83.8 Expressed in all +PGS1 DKFZP762M186 ENSG00000087157 Phosphatidylglycerophosphate synthase 1 17 78378640-78425114 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022526 Approved Approved Vesicles
Cell Junctions
Intermediate filaments Renal cancer:1.16e-5 (unfavourable), Pancreatic cancer:7.33e-5 (favourable), Liver cancer:1.37e-4 (unfavourable), Prostate cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 26.7 Expressed in all +PSMC5 p45, p45/SUG, S8, SUG-1, SUG1, TBP10, TRIP1 ENSG00000087191 Proteasome 26S subunit, ATPase 5 17 63827152-63832026 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017871, HPA064293 Enhanced Supported Plasma membrane
Cytosol Renal cancer:3.13e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 251.4 Expressed in all +UIMC1 RAP80 ENSG00000087206 Ubiquitin interaction motif containing 1 5 176905005-177022633 Predicted intracellular proteins Evidence at protein level HPA037503, HPA037504 Enhanced Enhanced Nuclear bodies Liver cancer:7.67e-6 (unfavourable) Expressed in all Expressed in all testis: 109.5 Expressed in all +CETP BPIFF ENSG00000087237 Cholesteryl ester transfer protein 16 56961850-56983845 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level Mixed Group enriched 6 adipose tissue: 36.9;liver: 21.7;lymph node: 46.3;placenta: 50.4;spleen: 77.7 thyroid gland: 8.4 Cell line enhanced HEL: 2.4;HUVEC TERT2: 3.6;TIME: 2.1 +MMP2 CLG4, CLG4A, TBE-1 ENSG00000087245 Matrix metallopeptidase 2 16 55389700-55506691 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001939, CAB002788 Approved Uncertain Vesicles
Cytosol Expressed in all Tissue enhanced gallbladder: 1682.1 urinary bladder: 910.7 Cell line enhanced ASC diff: 3859.6;U-138 MG: 1525.4;U-87 MG: 1772.5 +MT3 GIF ENSG00000087250 Metallothionein 3 16 56589074-56591088 Predicted intracellular proteins Evidence at protein level HPA004011, CAB017779 Enhanced Tissue enriched Tissue enriched 17 cerebral cortex: 738.6 adrenal gland: 42.9 Group enriched 7 RPMI-8226: 3.1;SCLC-21H: 8.7;U-87 MG: 12.1 +LPCAT2 AGPAT11, AYTL1, FLJ20481, LysoPAFAT ENSG00000087253 Lysophosphatidylcholine acyltransferase 2 16 55508998-55586670 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007891, HPA008433 Enhanced Supported Enhanced Endoplasmic reticulum
Lipid droplets Endometrial cancer:8.03e-6 (favourable), Colorectal cancer:3.43e-4 (favourable) Expressed in all Tissue enhanced thyroid gland: 142.6 bone marrow: 56.4 Cell line enhanced CAPAN-2: 100.9;HMC-1: 141.4;WM-115: 114.8 +GNAO1 G-ALPHA-o ENSG00000087258 G protein subunit alpha o1 16 56191347-56357457 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB008387, HPA040878 Enhanced Pancreatic cancer:5.93e-4 (favourable) Tissue enriched Tissue enriched 7 cerebral cortex: 166.9 seminal vesicle: 22.6 Cell line enhanced BJ hTERT+: 24.8;BJ hTERT+ SV40 Large T+: 18.7;SCLC-21H: 72.2 +OGFOD1 FLJ10826, KIAA1612, TPA1 ENSG00000087263 2-oxoglutarate and iron dependent oxygenase domain containing 1 16 56451490-56479100 Predicted intracellular proteins Evidence at protein level HPA003215 Approved Approved Supported Nucleus
Cytosol Head and neck cancer:6.65e-4 (unfavourable), Liver cancer:7.02e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 22.1 Expressed in all +SH3BP2 CRBM, RES4-23 ENSG00000087266 SH3 domain binding protein 2 4 2793023-2841098 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036790 Approved Approved Nucleus
Actin filaments Endometrial cancer:5.42e-6 (unfavourable), Head and neck cancer:1.57e-5 (favourable), Urothelial cancer:2.67e-4 (favourable) Expressed in all Expressed in all spleen: 60.9 Mixed +NOP14 C4orf9, NOL14, RES4-25, UTP2 ENSG00000087269 NOP14 nucleolar protein 4 2937933-2963385 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039596, HPA055652 Approved Enhanced Nucleus
Nucleoli Colorectal cancer:3.93e-5 (favourable), Liver cancer:9.10e-4 (unfavourable) Expressed in all Expressed in all lymph node: 27.3 Expressed in all +ADD1 ENSG00000087274 Adducin 1 4 2843857-2930076 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009794, HPA035873, HPA035874 Enhanced Enhanced Nucleoplasm
Plasma membrane Renal cancer:1.29e-7 (favourable), Pancreatic cancer:3.94e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 201.1 Expressed in all +L2HGDH C14orf160, FLJ12618 ENSG00000087299 L-2-hydroxyglutarate dehydrogenase 14 50237563-50312548 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA065409, HPA069708 Approved Enhanced Mitochondria Renal cancer:9.75e-10 (favourable) Expressed in all Mixed kidney: 20.8 Expressed in all +TXNDC16 KIAA1344 ENSG00000087301 Thioredoxin domain containing 16 14 52430590-52552522 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002543 Approved Approved Mitochondria Renal cancer:6.79e-4 (favourable) Expressed in all Tissue enhanced prostate: 43.0 seminal vesicle: 18.3 Cell line enhanced SCLC-21H: 34.2 +C14orf166 CGI-99, CLE, CLE7, hCLE1, LCRP369, RLLM1 ENSG00000087302 Chromosome 14 open reading frame 166 14 51989475-52010691 Predicted intracellular proteins Evidence at protein level HPA039824 Supported Supported Nucleoplasm Expressed in all Expressed in all testis: 262.6 Expressed in all +NID2 ENSG00000087303 Nidogen 2 14 52004803-52069228 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA052460, HPA058772 Enhanced Supported Plasma membrane Urothelial cancer:2.78e-4 (unfavourable), Stomach cancer:7.34e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 88.5 thyroid gland: 54.1 Cell line enhanced ASC diff: 198.6;BJ: 133.5;HHSteC: 134.5;HSkMC: 435.7 +GMCL1 BTBD13, FLJ13057, GCL1, SPATA29 ENSG00000087338 Germ cell-less, spermatogenesis associated 1 2 69829642-69881396 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039579 Approved Expressed in all Expressed in all testis: 39.4 Expressed in all +SF3B2 Cus1, SAP145, SF3b1, SF3b145 ENSG00000087365 Splicing factor 3b subunit 2 11 66050729-66069308 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045028 Supported Enhanced Nuclear speckles Renal cancer:3.51e-5 (favourable), Liver cancer:6.43e-5 (unfavourable) Expressed in all Expressed in all testis: 192.7 Expressed in all +KLHL42 Ctb9, KIAA1340, KLHDC5 ENSG00000087448 Kelch like family member 42 12 27780020-27803040 Predicted intracellular proteins Evidence at protein level HPA020979 Uncertain Renal cancer:2.98e-4 (unfavourable) Expressed in all Mixed smooth muscle: 32.9 Expressed in all +GNAS GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI ENSG00000087460 GNAS complex locus 20 58839718-58911192 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010337, HPA018122, HPA027478, HPA028386 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:3.49e-4 (unfavourable), Ovarian cancer:8.76e-4 (favourable) Expressed in all Expressed in all thyroid gland: 1473.9 Expressed in all +DNM1L DRP1, DVLP, DYMPLE, HDYNIV, VPS1 ENSG00000087470 Dynamin 1 like 12 32679200-32745650 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB009952, HPA039324 Enhanced Enhanced Vesicles
Cytosol Liver cancer:6.27e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 88.1 Expressed in all +PTHLH HHM, PLP, PTHR, PTHRP ENSG00000087494 Parathyroid hormone like hormone 12 27958084-27972705 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level HPA035982 Approved Approved Supported Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:1.82e-9 (unfavourable), Liver cancer:3.37e-4 (unfavourable) Tissue enhanced Tissue enhanced breast: 23.9 esophagus: 18.0 Group enriched 7 HaCaT: 256.2;HBEC3-KT: 257.7;U-251 MG: 64.3 +PHACTR3 C20orf101, PPP1R123 ENSG00000087495 Phosphatase and actin regulator 3 20 59577509-59847711 Predicted intracellular proteins Evidence at protein level HPA051834, HPA054847 Enhanced Nucleoplasm Group enriched Tissue enriched 9 cerebral cortex: 64.8 spleen: 7.4 Cell line enhanced RPTEC TERT1: 18.7;THP-1: 88.0;U-937: 25.4 +ERGIC2 Erv41, PTX1 ENSG00000087502 ERGIC and golgi 2 12 29337352-29381189 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049695 Approved Supported Nucleoli
Vesicles Renal cancer:3.76e-6 (unfavourable), Pancreatic cancer:7.02e-6 (unfavourable), Liver cancer:8.06e-6 (unfavourable), Ovarian cancer:8.18e-4 (favourable) Expressed in all Expressed in all testis: 106.3 Expressed in all +TFAP2C AP2-GAMMA, ERF1, hAP-2g, TFAP2G ENSG00000087510 Transcription factor AP-2 gamma 20 56629302-56639283 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB016061, CAB016079, HPA055179, HPA057076 Enhanced Supported Nucleoplasm Cervical cancer:6.90e-4 (favourable) Tissue enhanced Tissue enhanced skin: 63.0 breast: 31.6 Cell line enhanced BEWO: 183.4;MCF7: 128.7;SK-BR-3: 231.1;WM-115: 112.9 +AURKA AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7 ENSG00000087586 Aurora kinase A 20 56369389-56392337 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001454, HPA002636 Approved Approved Nucleus
Centrosome
Cytosol Renal cancer:1.47e-8 (unfavourable), Endometrial cancer:9.40e-5 (unfavourable), Liver cancer:1.49e-4 (unfavourable), Pancreatic cancer:6.13e-4 (unfavourable) Expressed in all Tissue enhanced testis: 53.5 lymph node: 24.0 Expressed in all +CASS4 C20orf32, HEFL, HEPL ENSG00000087589 Cas scaffolding protein family member 4 20 56412112-56460387 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034217 Approved Mixed Tissue enhanced appendix: 17.7;lung: 23.9 spleen: 10.7 Cell line enhanced HEL: 15.8;HMC-1: 45.4;K-562: 19.8 +PIR ENSG00000087842 Pirin X 15384799-15493564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000697 Enhanced Supported Cytosol Renal cancer:6.11e-7 (unfavourable), Cervical cancer:2.78e-4 (favourable), Ovarian cancer:4.94e-4 (favourable) Expressed in all Mixed urinary bladder: 22.6 Cell line enhanced HUVEC TERT2: 565.7;SK-MEL-30: 201.8 +AAMDC C11orf67, CK067, FLJ21035, PTD015 ENSG00000087884 Adipogenesis associated Mth938 domain containing 11 77821109-77918432 Predicted intracellular proteins Evidence at protein level HPA037918, HPA037919 Enhanced Approved Nucleoplasm
Cytosol Expressed in all Expressed in all skeletal muscle: 231.6 Expressed in all +RFX2 FLJ14226 ENSG00000087903 Regulatory factor X2 19 5993164-6199572 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048969 Enhanced Approved Nucleoplasm
Golgi apparatus
Cytosol Endometrial cancer:2.67e-4 (favourable), Cervical cancer:2.80e-4 (favourable), Pancreatic cancer:7.36e-4 (favourable) Mixed Tissue enhanced testis: 93.1 fallopian tube: 32.8 Cell line enhanced SCLC-21H: 27.7 +METTL2A FLJ12760, METTL2 ENSG00000087995 Methyltransferase like 2A 17 62423867-62450822 Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:2.31e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 9.0 Expressed in all +SULT2B1 HSST2 ENSG00000088002 Sulfotransferase family 2B member 1 19 48552075-48599425 Enzymes, Predicted intracellular proteins Evidence at protein level CAB033013, HPA041724, HPA043539 Approved Supported Vesicles
Cytosol Mixed Tissue enhanced esophagus: 152.2;skin: 152.4 cervix, uterine: 45.8 Cell line enhanced CAPAN-2: 59.3;MCF7: 32.5;T-47d: 31.4 +ALG6 ENSG00000088035 ALG6, alpha-1,3-glucosyltransferase 1 63367590-63438562 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA062536 Supported Endoplasmic reticulum Renal cancer:2.63e-6 (unfavourable), Colorectal cancer:4.86e-4 (favourable), Liver cancer:9.46e-4 (unfavourable) Expressed in all Mixed placenta: 11.9 Expressed in all +CNOT3 KIAA0691, LENG2, NOT3, NOT3H ENSG00000088038 CCR4-NOT transcription complex subunit 3 19 54137728-54155681 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA006408 Approved Approved Cytosol Liver cancer:2.22e-4 (unfavourable), Renal cancer:2.77e-4 (unfavourable) Expressed in all Expressed in all testis: 36.1 Expressed in all +GP6 GPVI ENSG00000088053 Glycoprotein VI platelet 19 55013705-55038264 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA066482 Approved Approved Nucleoplasm Not detected Tissue enhanced testis: 1.2 skin: 0.7 Group enriched 12 HEL: 8.5;K-562: 3.7;U-2 OS: 2.7 +PTPN4 PTPMEG ENSG00000088179 Protein tyrosine phosphatase, non-receptor type 4 2 119759631-119983818 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019351 Uncertain Approved Nucleus
Plasma membrane
Cytosol Lung cancer:5.16e-4 (favourable) Expressed in all Mixed thyroid gland: 24.5 Mixed +DDX18 MrDb ENSG00000088205 DEAD-box helicase 18 2 117814650-117832379 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035400, HPA041056 Approved Enhanced Nucleoli Endometrial cancer:2.64e-4 (unfavourable), Liver cancer:3.07e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 49.6 Expressed in all +KHSRP FBP2, FUBP2, KSRP ENSG00000088247 KH-type splicing regulatory protein 19 6413348-6424794 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034739, HPA056518 Enhanced Enhanced Nucleoplasm Renal cancer:2.56e-4 (unfavourable) Expressed in all Expressed in all testis: 179.1 Expressed in all +GNA11 FBH, FBH2, FHH2, HHC2 ENSG00000088256 G protein subunit alpha 11 19 3094410-3124004 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA048886 Approved Renal cancer:1.48e-11 (favourable), Liver cancer:4.86e-4 (unfavourable) Expressed in all Expressed in all small intestine: 155.9 Expressed in all +ASAP3 CENTB6, DDEFL1, FLJ20199, UPLC1 ENSG00000088280 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1 23428563-23484568 Predicted intracellular proteins Evidence at protein level HPA020537, HPA020546 Approved Supported Nucleoplasm
Vesicles Renal cancer:5.12e-5 (favourable), Lung cancer:2.80e-4 (favourable), Endometrial cancer:5.56e-4 (unfavourable), Ovarian cancer:8.30e-4 (unfavourable) Expressed in all Mixed skin: 32.5 Cell line enhanced HSkMC: 27.9 +EDEM2 bA4204.1, C20orf31, C20orf49, FLJ10783 ENSG00000088298 ER degradation enhancing alpha-mannosidase like protein 2 20 35115357-35147364 Predicted secreted proteins Evidence at protein level CAB037238, HPA048353 Approved Renal cancer:4.76e-6 (unfavourable) Expressed in all Expressed in all epididymis: 54.7 Expressed in all +DNMT3B ENSG00000088305 DNA methyltransferase 3 beta 20 32762385-32809356 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001595, CAB069896 Enhanced Approved Nucleoplasm
Vesicles Renal cancer:1.87e-7 (unfavourable), Endometrial cancer:5.04e-4 (unfavourable) Tissue enriched Tissue enhanced testis: 9.2 skin: 4.5 Cell line enhanced BEWO: 236.9;NTERA-2: 333.3 +REM1 GES, REM ENSG00000088320 RRAD and GEM like GTPase 1 20 31475293-31484905 Predicted intracellular proteins Evidence at protein level HPA049821 Approved Renal cancer:1.84e-6 (unfavourable) Mixed Mixed cervix, uterine: 12.3 Cell line enriched 35 WM-115: 21.8 +TPX2 C20orf1, C20orf2, DIL-2, p100 ENSG00000088325 TPX2, microtubule nucleation factor 20 31739271-31801805 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA005487 Enhanced Enhanced Nucleoplasm
Cytokinetic bridge
Mitotic spindle
Microtubule organizing center Renal cancer:0.00e+0 (unfavourable), Liver cancer:8.07e-7 (unfavourable), Endometrial cancer:2.43e-6 (unfavourable), Pancreatic cancer:2.68e-5 (unfavourable), Lung cancer:6.46e-4 (unfavourable) Expressed in all Tissue enhanced testis: 55.6 lymph node: 31.4 Expressed in all +PDRG1 C20orf126, dJ310O13.3 ENSG00000088356 P53 and DNA damage regulated 1 20 31944342-31952092 Predicted intracellular proteins Evidence at protein level HPA047084, HPA063542 Approved Approved Actin filaments Liver cancer:2.62e-5 (unfavourable), Endometrial cancer:1.69e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 64.5 Expressed in all +EPB41L1 4.1N, KIAA0338 ENSG00000088367 Erythrocyte membrane protein band 4.1 like 1 20 36091504-36232799 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA054104, HPA056817 Enhanced Supported Plasma membrane Renal cancer:4.39e-10 (favourable), Endometrial cancer:6.46e-5 (unfavourable), Pancreatic cancer:9.30e-4 (unfavourable) Expressed in all Mixed adrenal gland: 162.4 Cell line enhanced HaCaT: 212.9 +SLC15A1 HPECT1, HPEPT1, PEPT1 ENSG00000088386 Solute carrier family 15 member 1 13 98683801-98752654 Predicted membrane proteins, Transporters Evidence at protein level HPA002827 Uncertain Approved Nucleoplasm
Cytosol Mixed Group enriched 5 duodenum: 153.2;gallbladder: 67.7;small intestine: 225.0 skin: 27.8 Group enriched 6 CAPAN-2: 49.1;SK-BR-3: 41.2 +DOCK9 KIAA1058, ZIZ1 ENSG00000088387 Dedicator of cytokinesis 9 13 98793429-99086625 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034061, CAB034065, HPA043940 Uncertain Expressed in all Expressed in all placenta: 141.8 Cell line enhanced BEWO: 190.5;hTERT-HME1: 334.6 +ANKRD10 FLJ20093 ENSG00000088448 Ankyrin repeat domain 10 13 110878540-110915069 Predicted intracellular proteins Evidence at protein level CAB034211, HPA038878, HPA038879 Uncertain Approved Microtubules
Cytosol Renal cancer:1.25e-6 (unfavourable), Urothelial cancer:6.41e-6 (favourable) Expressed in all Expressed in all epididymis: 109.5 Expressed in all +TGDS SDR2E1, TDPGD ENSG00000088451 TDP-glucose 4,6-dehydratase 13 94574051-94596257 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039927, HPA040857 Approved Approved Nucleus
Nucleoli
Intermediate filaments
Cleavage furrow Prostate cancer:2.48e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 21.7 Expressed in all +DOCK3 KIAA0299, MOCA, PBP ENSG00000088538 Dedicator of cytokinesis 3 3 50675241-51384198 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037543, HPA037544 Approved Enhanced Cytosol Tissue enhanced Group enriched 6 cerebral cortex: 33.7;parathyroid gland: 12.6;testis: 8.5;thyroid gland: 15.1 adrenal gland: 3.0 Cell line enhanced AN3-CA: 5.9;U-87 MG: 8.0 +C3orf18 G20 ENSG00000088543 Chromosome 3 open reading frame 18 3 50558025-50571027 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA012105 Approved Approved Cytosol Renal cancer:2.80e-9 (favourable) Expressed in all Mixed parathyroid gland: 28.3 Cell line enhanced HDLM-2: 45.2 +COQ9 C16orf49, DKFZP434K046 ENSG00000088682 Coenzyme Q9 16 57447425-57461275 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040918 Supported Approved Cytosol Renal cancer:9.03e-11 (favourable) Expressed in all Expressed in all parathyroid gland: 90.6 Expressed in all +TMEM40 FLJ11036 ENSG00000088726 Transmembrane protein 40 3 12733525-12769457 Predicted membrane proteins Evidence at protein level HPA044165 Enhanced Approved Cytosol Tissue enhanced Group enriched 8 esophagus: 88.8;placenta: 23.3;skin: 55.5;tonsil: 23.7 urinary bladder: 6.1 Cell line enhanced HBEC3-KT: 182.0;hTCEpi: 40.5;hTERT-HME1: 54.0 +KIF9 MGC104186 ENSG00000088727 Kinesin family member 9 3 47228026-47283451 Predicted intracellular proteins Evidence at protein level HPA022031, HPA022033, HPA030429 Approved Approved Nucleus
Nucleoli Renal cancer:5.95e-6 (favourable), Colorectal cancer:2.26e-4 (favourable) Expressed in all Expressed in all testis: 87.6 Expressed in all +ARHGAP28 FLJ10312, KIAA1314 ENSG00000088756 Rho GTPase activating protein 28 18 6729718-6915716 Predicted intracellular proteins Evidence at protein level HPA030413, HPA030414, HPA030415 Enhanced Supported Cell Junctions Mixed Tissue enhanced testis: 133.0 placenta: 40.9 Cell line enhanced AF22: 35.5;CACO-2: 31.8 +CRLS1 C20orf155, CLS1, dJ967N21.6, GCD10 ENSG00000088766 Cardiolipin synthase 1 20 6006090-6040053 Enzymes, Predicted membrane proteins Evidence at protein level Urothelial cancer:8.02e-4 (favourable) Expressed in all Expressed in all liver: 87.0 Expressed in all +DEFB127 bA530N10.2, C20orf73, DEF-27 ENSG00000088782 Defensin beta 127 20 157470-159163 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 1015 epididymis: 1399.7 seminal vesicle: 1.3 Not detected +PPP1R13B ASPP1, KIAA0771, p53BP2-like, p85 ENSG00000088808 Protein phosphatase 1 regulatory subunit 13B 14 103733752-103847590 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006394, CAB015454 Approved Supported Nucleoplasm
Cytosol Renal cancer:3.28e-11 (favourable), Lung cancer:1.41e-4 (favourable) Expressed in all Mixed thyroid gland: 43.9 Mixed +ATRN DPPT-L, MGCA ENSG00000088812 Attractin 20 3471040-3651122 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA008853 Uncertain Approved Cytosol Renal cancer:2.19e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 84.8 Mixed +SMOX C20orf16, dJ779E11.1, FLJ20746, MGC1010, PAO, PAOh1, SMO ENSG00000088826 Spermine oxidase 20 4120980-4187747 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA047117, HPA060198 Approved Supported Nucleoplasm
Nuclear membrane
Vesicles Liver cancer:3.33e-6 (unfavourable), Renal cancer:1.06e-4 (unfavourable), Lung cancer:1.36e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 49.7 gallbladder: 23.5 Cell line enhanced A549: 104.6;Karpas-707: 139.7 +SIGLEC1 CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN ENSG00000088827 Sialic acid binding Ig like lectin 1 20 3686970-3707128 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053457 Supported Renal cancer:8.69e-5 (unfavourable), Testis cancer:4.36e-4 (unfavourable) Expressed in all Mixed placenta: 27.3 Cell line enriched 14 THP-1: 1.4 +FKBP1A FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE ENSG00000088832 FK506 binding protein 1A 20 1368978-1393172 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB004639, HPA051798 Uncertain Liver cancer:3.44e-7 (unfavourable), Renal cancer:6.69e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 369.7 Expressed in all +NSFL1C dJ776F14.1, p47, UBX1, UBXD10, UBXN2C ENSG00000088833 NSFL1 cofactor 20 1442162-1473842 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047108, HPA050628 Enhanced Enhanced Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.29e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 35.4 Expressed in all +SLC4A11 BTR1, CDPD1, CHED2, dJ794I6.2, FECD4, NaBC1 ENSG00000088836 Solute carrier family 4 member 11 20 3227417-3239190 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018120, HPA058377 Uncertain Uncertain Nucleoplasm
Vesicles Renal cancer:6.21e-6 (favourable), Cervical cancer:9.03e-4 (favourable) Expressed in all Tissue enhanced thyroid gland: 27.7 salivary gland: 19.2 Cell line enhanced HaCaT: 55.7 +C20orf194 DKFZp434N061 ENSG00000088854 Chromosome 20 open reading frame 194 20 3249305-3407625 Predicted intracellular proteins Evidence at protein level HPA052103, HPA067418 Approved Approved Nucleoli fibrillar center
Cytosol Pancreatic cancer:1.68e-4 (favourable), Renal cancer:7.68e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 26.4 Mixed +ZNF343 MGC10715 ENSG00000088876 Zinc finger protein 343 20 2481817-2524702 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030587, HPA052438 Approved Approved Nucleoplasm Liver cancer:1.38e-6 (unfavourable), Renal cancer:4.53e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 15.6 Expressed in all +EBF4 COE4, KIAA1442, O/E-4, RP5-860F19.3 ENSG00000088881 Early B-cell factor 4 20 2692878-2760108 Predicted intracellular proteins, Transcription factors Evidence at transcript level Pancreatic cancer:2.47e-5 (favourable), Colorectal cancer:6.59e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 23.7 Cell line enhanced SH-SY5Y: 15.8 +CPXM1 CPX-1, CPX1, CPXM ENSG00000088882 Carboxypeptidase X, M14 family member 1 20 2794069-2800637 Enzymes, Predicted secreted proteins Evidence at protein level Renal cancer:4.62e-10 (unfavourable) Expressed in all Tissue enhanced endometrium: 130.4;gallbladder: 132.2 urinary bladder: 75.0 Group enriched 5 AF22: 158.5;HSkMC: 62.0;NB-4: 92.9;NTERA-2: 34.2;REH: 136.3;SH-SY5Y: 113.9 +MAVS Cardif, IPS-1, KIAA1271, VISA ENSG00000088888 Mitochondrial antiviral signaling protein 20 3846799-3876123 Predicted membrane proteins Evidence at protein level CAB009187, HPA049850, HPA053524 Enhanced Enhanced Mitochondria Renal cancer:4.13e-5 (favourable), Pancreatic cancer:3.81e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.6 Expressed in all +LZTS3 KIAA0552, ProSAPiP1 ENSG00000088899 Leucine zipper tumor suppressor family member 3 20 3162617-3173592 Predicted intracellular proteins Evidence at protein level HPA031008, HPA031009 Approved Approved Vesicles Renal cancer:5.92e-8 (favourable), Endometrial cancer:7.26e-4 (unfavourable), Lung cancer:7.98e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 58.6 parathyroid gland: 20.3 Cell line enhanced SCLC-21H: 21.3 +F11 FXI ENSG00000088926 Coagulation factor XI 4 186265945-186288806 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039808 Approved Vesicles Liver cancer:3.29e-5 (favourable) Tissue enriched Tissue enhanced liver: 180.1 kidney: 44.7 Cell line enriched 8 Hep G2: 6.0 +XRN2 ENSG00000088930 5'-3' exoribonuclease 2 20 21303304-21389827 Predicted intracellular proteins Evidence at protein level HPA047118, HPA050485 Supported Enhanced Nucleus
Nucleoli Liver cancer:3.54e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 75.0 Expressed in all +KIZ C20orf19, HT013, NCRNA00153, PLK1S1 ENSG00000088970 Kizuna centrosomal protein 20 21125983-21246622 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.11e-8 (unfavourable), Endometrial cancer:4.45e-4 (favourable) Expressed in all Expressed in all testis: 82.2 Expressed in all +DYNLL1 DLC1, DLC8, DNCL1, hdlc1, LC8, PIN ENSG00000088986 Dynein light chain LC8-type 1 12 120469850-120498493 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039954 Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:7.97e-7 (unfavourable), Liver cancer:7.33e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 772.7 Expressed in all +TESC CHP3, FLJ20607, TSC ENSG00000088992 Tescalcin 12 117038923-117099479 Predicted intracellular proteins Evidence at protein level HPA053200 Enhanced Supported Nucleus
Cytosol Expressed in all Tissue enhanced epididymis: 135.9;salivary gland: 131.3;stomach: 118.8 bone marrow: 67.0 Cell line enhanced HMC-1: 320.8;NB-4: 389.7;U-937: 158.6 +SNX5 ENSG00000089006 Sorting nexin 5 20 17941597-17968980 Predicted intracellular proteins Evidence at protein level CAB020679, HPA051187 Approved Liver cancer:2.30e-10 (unfavourable) Expressed in all Expressed in all thyroid gland: 132.4 Expressed in all +RPL6 L6, TAXREB107, TXREB1 ENSG00000089009 Ribosomal protein L6 12 112405190-112418838 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA060903, HPA068418 Approved Approved Microtubules
Cytokinetic bridge Renal cancer:6.95e-4 (unfavourable) Expressed in all Expressed in all ovary: 3221.7 Expressed in all +SIRPG bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma ENSG00000089012 Signal regulatory protein gamma 20 1629152-1657779 CD markers, Predicted membrane proteins Evidence at protein level Melanoma:7.36e-7 (favourable), Endometrial cancer:1.05e-6 (favourable), Renal cancer:1.47e-6 (unfavourable), Head and neck cancer:2.24e-4 (favourable) Mixed Tissue enhanced lymph node: 38.8;tonsil: 25.8 appendix: 16.9 Cell line enhanced NB-4: 8.6;RT4: 2.8;THP-1: 1.6 +MAPKAPK5 PRAK ENSG00000089022 Mitogen-activated protein kinase-activated protein kinase 5 12 111841978-111902238 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB004546, HPA015515 Supported Supported Nucleoplasm
Cytosol Liver cancer:2.98e-8 (unfavourable) Expressed in all Expressed in all rectum: 33.8 Expressed in all +P2RX7 MGC20089, P2X7 ENSG00000089041 Purinergic receptor P2X 7 12 121132819-121188032 Predicted membrane proteins, Transporters Evidence at protein level HPA034967, HPA034968, HPA042013, HPA044141 Approved Approved Golgi apparatus Renal cancer:2.92e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 21.0 Cell line enhanced Karpas-707: 28.5;RPMI-8226: 16.7;SK-MEL-30: 31.3;U-266/70: 16.4;U-266/84: 14.0 +ESF1 bA526K24.1, C20orf6 ENSG00000089048 ESF1 nucleolar pre-rRNA processing protein homolog 20 13714322-13784886 Predicted intracellular proteins Evidence at protein level HPA047083, HPA050396 Supported Approved Nucleus
Nucleoli Liver cancer:7.81e-9 (unfavourable) Expressed in all Expressed in all testis: 25.9 Expressed in all +RBBP9 Bog ENSG00000089050 RB binding protein 9, serine hydrolase 20 18486540-18497243 Predicted intracellular proteins Evidence at protein level HPA015830, HPA049005 Approved Supported Nucleoplasm Expressed in all Expressed in all thyroid gland: 40.8 Expressed in all +ANAPC5 APC5 ENSG00000089053 Anaphase promoting complex subunit 5 12 121308245-121399896 Predicted intracellular proteins Evidence at protein level HPA039457, HPA039801 Supported Approved Nucleoplasm Renal cancer:2.01e-9 (unfavourable), Liver cancer:2.31e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 88.7 Expressed in all +SLC23A2 KIAA0238, SLC23A1, SVCT2, YSPL2 ENSG00000089057 Solute carrier family 23 member 2 20 4852356-5010293 Predicted membrane proteins, Transporters Evidence at protein level HPA052825, HPA059314 Approved Supported Golgi apparatus
Vesicles Urothelial cancer:6.08e-5 (favourable), Pancreatic cancer:7.14e-5 (favourable), Liver cancer:3.35e-4 (favourable) Expressed in all Expressed in all adrenal gland: 98.2 Expressed in all +SLC8B1 FLJ22233, NCKX6, NCLX, SLC24A6 ENSG00000089060 Solute carrier family 8 member B1 12 113298759-113359493 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA040668 Approved Urothelial cancer:5.02e-4 (favourable), Breast cancer:9.52e-4 (favourable) Expressed in all Expressed in all adrenal gland: 48.4 Mixed +TMEM230 C20orf30, HSPC274 ENSG00000089063 Transmembrane protein 230 20 5068232-5113103 Predicted membrane proteins Evidence at protein level HPA009078, HPA061421 Uncertain Enhanced Endoplasmic reticulum Expressed in all Expressed in all thyroid gland: 227.2 Expressed in all +DZANK1 ANKRD64, bA189K21.8, C20orf12, C20orf84, dJ568F9.2, FLJ10600, FLJ30892 ENSG00000089091 Double zinc ribbon and ankyrin repeat domains 1 20 18383367-18467281 Predicted intracellular proteins Evidence at protein level HPA059478, HPA064255 Uncertain Approved Nucleoli fibrillar center Mixed Mixed fallopian tube: 5.2 Cell line enhanced THP-1: 17.4;U-266/84: 19.5 +KDM2B CXXC2, Fbl10, FBXL10, JHDM1B, PCCX2 ENSG00000089094 Lysine demethylase 2B 12 121429097-121581015 Enzymes, Predicted intracellular proteins Evidence at protein level HPA071257 Uncertain Nucleoplasm Head and neck cancer:6.74e-6 (favourable), Pancreatic cancer:8.64e-4 (favourable) Expressed in all Expressed in all lymph node: 35.8 Expressed in all +CFAP61 C20orf26, CaM-IP3, dJ1002M8.3, DKFZP434K156 ENSG00000089101 Cilia and flagella associated protein 61 20 20052514-20360702 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA009079 Uncertain Mixed Group enriched 6 fallopian tube: 20.3;heart muscle: 8.5;testis: 29.5 skeletal muscle: 3.3 Cell line enhanced HMC-1: 2.1;SCLC-21H: 6.6;U-87 MG: 4.1 +LHX5 ENSG00000089116 LIM homeobox 5 12 113462034-113472280 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA053908 Uncertain Mixed Tissue enhanced cerebral cortex: 1.4 stomach: 0.3 Cell line enhanced HMC-1: 1.0 +TASP1 C20orf13, dJ585I14.2, FLJ20212 ENSG00000089123 Taspase 1 20 13389392-13638940 Predicted intracellular proteins Evidence at protein level HPA030824, HPA030825 Uncertain Approved Plasma membrane Thyroid cancer:6.78e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 13.7 Mixed +OAS1 IFI-4, OIAS, OIASI ENSG00000089127 2'-5'-oligoadenylate synthetase 1 12 112906777-112933222 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003657, CAB021104 Uncertain Approved Cytosol Urothelial cancer:6.12e-6 (favourable), Pancreatic cancer:3.02e-4 (unfavourable) Expressed in all Expressed in all spleen: 90.1 Cell line enhanced BJ hTERT+ SV40 Large T+: 266.2;BJ hTERT+ SV40 Large T+ RasG12V: 396.9;U-266/70: 307.4;U-266/84: 229.8 +GCN1 GCN1L, GCN1L1, KIAA0219 ENSG00000089154 GCN1, eIF2 alpha kinase activator homolog 12 120127203-120194710 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018799, HPA019648, HPA024367 Enhanced Enhanced Cytosol Liver cancer:1.87e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 37.5 Expressed in all +RPLP0 L10E, LP0, P0, PRLP0, RPP0 ENSG00000089157 Ribosomal protein lateral stalk subunit P0 12 120196686-120201235 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003512 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:7.66e-12 (unfavourable) Expressed in all Expressed in all breast: 2860.7 Expressed in all +PXN ENSG00000089159 Paxillin 12 120210439-120265771 Predicted intracellular proteins Evidence at protein level CAB003841, HPA051309 Enhanced Enhanced Focal adhesion sites
Centrosome
Cytosol Head and neck cancer:3.72e-5 (unfavourable), Glioma:6.11e-5 (unfavourable), Liver cancer:7.12e-5 (unfavourable), Lung cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all placenta: 100.4 Expressed in all +SIRT4 SIR2L4 ENSG00000089163 Sirtuin 4 12 120302316-120313249 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA029691, HPA029692 Enhanced Renal cancer:1.75e-4 (favourable) Mixed Mixed testis: 9.5 Mixed +RPH3A exophilin-1, KIAA0985, rabphilin ENSG00000089169 Rabphilin 3A 12 112570380-112898881 Predicted intracellular proteins Evidence at protein level HPA002475 Enhanced Tissue enriched Tissue enriched 7 cerebral cortex: 95.2 bone marrow: 13.8 Cell line enhanced SH-SY5Y: 17.7 +KIF16B C20orf23, dJ971B4.1, FLJ20135, SNX23 ENSG00000089177 Kinesin family member 16B 20 16272104-16573434 Predicted intracellular proteins Evidence at protein level HPA051198 Approved Uncertain Mitochondria Renal cancer:7.61e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 42.9 Mixed +TRMT6 CGI-09, GCD10, Gcd10p, MGC5029 ENSG00000089195 TRNA methyltransferase 6 20 5937235-5950558 Predicted intracellular proteins Evidence at protein level HPA047032, HPA050408 Approved Supported Nucleus Liver cancer:4.70e-12 (unfavourable) Expressed in all Expressed in all testis: 25.4 Expressed in all +CHGB SCG1, SgI ENSG00000089199 Chromogranin B 20 5911430-5925361 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008759, CAB009403, HPA012602 Enhanced Supported Enhanced Vesicles Head and neck cancer:1.89e-4 (unfavourable), Pancreatic cancer:9.96e-4 (favourable) Tissue enriched Tissue enriched 26 adrenal gland: 4382.4 cerebral cortex: 168.3 Group enriched 25 SCLC-21H: 405.5;SH-SY5Y: 559.4 +PEBP1 HCNP, PBP, PEBP, RKIP ENSG00000089220 Phosphatidylethanolamine binding protein 1 12 118135858-118145584 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008819, CAB013493, HPA063904 Enhanced Supported Plasma membrane Renal cancer:2.15e-13 (favourable), Pancreatic cancer:1.52e-4 (favourable) Expressed in all Expressed in all adrenal gland: 1642.0 Expressed in all +TBX5 HOS ENSG00000089225 T-box 5 12 114353931-114408442 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008786, HPA064683 Uncertain Approved Nucleoplasm Mixed Group enriched 6 heart muscle: 40.0;lung: 18.0;placenta: 46.8 prostate: 6.2 Cell line enhanced BJ: 17.0;BJ hTERT+: 36.2;BJ hTERT+ SV40 Large T+: 9.5;BJ hTERT+ SV40 Large T+ RasG12V: 12.1;HAP1: 18.0 +BRAP BRAP2, IMP, RNF52 ENSG00000089234 BRCA1 associated protein 12 111642146-111685986 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA040357, HPA058820 Approved Supported Nuclear membrane
Cytosol Liver cancer:7.65e-6 (unfavourable) Expressed in all Tissue enriched 6 testis: 120.9 bone marrow: 21.3 Expressed in all +ERP29 C12orf8, ERp28, ERp29, ERp31, PDI-DB, PDIA9 ENSG00000089248 Endoplasmic reticulum protein 29 12 112013316-112023451 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039363, HPA039456 Enhanced Uncertain Nucleoplasm
Microtubules Endometrial cancer:7.43e-5 (favourable), Liver cancer:2.02e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 150.9 Expressed in all +NOS1 nNOS, NOS ENSG00000089250 Nitric oxide synthase 1 12 117208142-117452170 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002167, HPA058312 Uncertain Supported Nucleoplasm
Plasma membrane Mixed Tissue enhanced skeletal muscle: 12.9 cerebral cortex: 3.0 Cell line enhanced HaCaT: 4.0;RH-30: 9.0;RPTEC TERT1: 4.4 +FUS ALS6, FUS1, hnRNP-P2, HNRNPP2, TLS ENSG00000089280 FUS RNA binding protein 16 31180110-31194871 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008784, CAB033036, CAB058691 Enhanced Enhanced Nucleoplasm Liver cancer:4.38e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 145.8 Expressed in all +IGBP1 IBP1 ENSG00000089289 Immunoglobulin binding protein 1 X 70133449-70166324 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000634, HPA001004, CAB034139 Approved Approved Microtubules Expressed in all Expressed in all ovary: 147.3 Expressed in all +FXYD5 OIT2 ENSG00000089327 FXYD domain containing ion transport regulator 5 19 35154730-35169883 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA010817 Uncertain Approved Endoplasmic reticulum Renal cancer:3.71e-9 (unfavourable) Expressed in all Expressed in all spleen: 237.1 Mixed +ZNF302 ZNF135L, ZNF140L, ZNF327 ENSG00000089335 Zinc finger protein 302 19 34677639-34686397 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059503 Approved Vesicles
Cytokinetic bridge Endometrial cancer:2.03e-5 (unfavourable), Urothelial cancer:9.85e-5 (favourable), Renal cancer:5.41e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.1 Mixed +GRAMD1A FLJ90346, KIAA1533 ENSG00000089351 GRAM domain containing 1A 19 34994784-35026471 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008852, HPA012570 Approved Approved Plasma membrane
Cytosol Renal cancer:7.95e-12 (unfavourable) Expressed in all Expressed in all lung: 36.5 Expressed in all +FXYD3 MAT-8, PLML ENSG00000089356 FXYD domain containing ion transport regulator 3 19 35115879-35124324 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010856 Enhanced Renal cancer:1.15e-6 (unfavourable) Expressed in all Tissue enhanced colon: 1455.6;rectum: 1952.1 stomach: 557.3 Cell line enhanced HaCaT: 792.6;hTCEpi: 1156.1;RT4: 686.4;SK-BR-3: 621.3;WM-115: 590.3 +HEPH CPL, KIAA0698 ENSG00000089472 Hephaestin X 66162549-66268867 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005824 Approved Renal cancer:7.00e-6 (unfavourable), Glioma:6.23e-4 (unfavourable) Expressed in all Mixed smooth muscle: 119.0 Cell line enhanced AF22: 28.1;HEL: 22.8;HSkMC: 26.1;K-562: 64.5;LHCN-M2: 23.8 +CDIP1 C16orf5, CDIP, LITAFL ENSG00000089486 Cell death inducing p53 target 1 16 4510675-4538828 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049352 Approved Supported Nucleoplasm
Centrosome Renal cancer:1.14e-6 (favourable), Pancreatic cancer:2.14e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 72.9 Cell line enhanced RPMI-8226: 99.5 +CMTM1 CKLFH, CKLFH1a, CKLFSF1 ENSG00000089505 CKLF like MARVEL transmembrane domain containing 1 16 66566393-66579137 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA013801, HPA017136 Uncertain Approved Nucleoplasm Pancreatic cancer:5.68e-5 (unfavourable) Mixed Tissue enriched 6 testis: 28.7 spleen: 4.4 Mixed +KCNH4 elk1, Kv12.3 ENSG00000089558 Potassium voltage-gated channel subfamily H member 4 17 42156891-42181278 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Not detected Tissue enhanced cerebral cortex: 1.8 appendix: 0.7 Cell line enhanced HDLM-2: 4.2;K-562: 3.8;RPMI-8226: 5.6;RT4: 2.3;U-266/70: 3.1 +GANAB G2AN, GIIA, GluII, KIAA0088 ENSG00000089597 Glucosidase II alpha subunit 11 62624826-62646726 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026874, HPA061426 Enhanced Approved Nuclear membrane
Endoplasmic reticulum
Cytosol Liver cancer:1.27e-5 (unfavourable), Urothelial cancer:9.54e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 295.2 Expressed in all +GMIP ARHGAP46 ENSG00000089639 GEM interacting protein 19 19629476-19643667 Predicted intracellular proteins Evidence at protein level HPA042484, HPA045481 Enhanced Enhanced Nucleoplasm
Plasma membrane
Cytosol Renal cancer:3.97e-5 (unfavourable), Stomach cancer:3.03e-4 (favourable), Urothelial cancer:5.15e-4 (favourable) Expressed in all Mixed spleen: 46.7 Expressed in all +RBM41 FLJ11016 ENSG00000089682 RNA binding motif protein 41 X 107064420-107118823 Predicted intracellular proteins Evidence at protein level HPA042881 Approved Approved Nuclear speckles
Cytosol Renal cancer:3.04e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 19.3 Expressed in all +BIRC5 API4, EPR-1, survivin ENSG00000089685 Baculoviral IAP repeat containing 5 17 78214186-78225636 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA002830, CAB004270 Enhanced Enhanced Cytokinetic bridge Renal cancer:0.00e+0 (unfavourable), Liver cancer:5.28e-6 (unfavourable), Lung cancer:4.49e-4 (unfavourable) Expressed in all Tissue enhanced testis: 26.8 bone marrow: 22.6 Mixed +LAG3 CD223 ENSG00000089692 Lymphocyte activating 3 12 6772512-6778455 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002301, HPA013967 Enhanced Renal cancer:4.62e-11 (unfavourable), Cervical cancer:3.89e-4 (favourable) Expressed in all Tissue enhanced spleen: 32.0 lymph node: 17.6 Cell line enriched 140 HDLM-2: 136.0 +MLF2 NTN4 ENSG00000089693 Myeloid leukemia factor 2 12 6747996-6767475 Predicted intracellular proteins Evidence at protein level HPA010811, HPA010859 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all cerebral cortex: 272.5 Expressed in all +OTUB2 C14orf137, FLJ21916, MGC3102 ENSG00000089723 OTU deubiquitinase, ubiquitin aldehyde binding 2 14 94026329-94048930 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002329 Enhanced Mixed Tissue enhanced testis: 9.7 skin: 4.7 Cell line enhanced Karpas-707: 12.8;RPTEC TERT1: 8.5 +DDX24 ENSG00000089737 DEAD-box helicase 24 14 94048291-94081245 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002554 Uncertain Approved Nucleoli
Cytosol Renal cancer:3.06e-9 (favourable), Stomach cancer:2.89e-4 (unfavourable) Expressed in all Tissue enhanced epididymis: 45.3 testis: 26.5 Mixed +ZBTB25 C14orf51, KUP, ZNF46 ENSG00000089775 Zinc finger and BTB domain containing 25 14 64449106-64505213 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054699 Uncertain Enhanced Nucleoplasm Renal cancer:3.56e-6 (unfavourable) Expressed in all Mixed thyroid gland: 14.8 Expressed in all +NECAP1 DKFZP566B183 ENSG00000089818 NECAP endocytosis associated 1 12 8076939-8097859 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053980, HPA063300 Uncertain Approved Vesicles
Cytosol Expressed in all Tissue enhanced cerebral cortex: 117.8 parathyroid gland: 34.8 Expressed in all +ARHGAP4 C1, KIAA0131, p115, RhoGAP4, SrGAP4 ENSG00000089820 Rho GTPase activating protein 4 X 153907367-153934999 Predicted intracellular proteins Evidence at protein level HPA001012, HPA001083 Enhanced Approved Nucleoplasm
Focal adhesion sites Colorectal cancer:1.97e-5 (unfavourable), Cervical cancer:3.94e-5 (favourable), Renal cancer:2.49e-4 (unfavourable), Head and neck cancer:3.31e-4 (favourable) Expressed in all Tissue enhanced spleen: 95.1 lymph node: 87.2 Cell line enhanced MOLT-4: 72.4;RPMI-8226: 121.4 +ANKRD24 KIAA1981 ENSG00000089847 Ankyrin repeat domain 24 19 4183354-4224814 Predicted intracellular proteins Evidence at protein level HPA041534, HPA048498 Uncertain Uncertain Microtubules
Cytosol Liver cancer:9.13e-5 (favourable) Mixed Tissue enhanced cerebral cortex: 13.5;testis: 7.0 prostate: 3.2 Cell line enhanced Karpas-707: 3.5;U-266/70: 12.3 +DHX32 DDX32, DHLP1, FLJ10694, FLJ10889 ENSG00000089876 DEAH-box helicase 32 (putative) 10 125836337-125896436 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048872 Approved Pancreatic cancer:9.49e-5 (unfavourable), Prostate cancer:6.34e-4 (unfavourable) Expressed in all Expressed in all testis: 59.8 Mixed +RCOR1 COREST, KIAA0071, RCOR ENSG00000089902 REST corepressor 1 14 102592661-102730576 Predicted secreted proteins Evidence at protein level CAB001956, HPA049327, HPA054241 Supported Enhanced Nucleoplasm Urothelial cancer:3.72e-4 (unfavourable) Expressed in all Expressed in all bone marrow,placenta: 29.6 Expressed in all +GPATCH2L C14orf118, FLJ10033, FLJ20689 ENSG00000089916 G-patch domain containing 2 like 14 76151916-76254342 Predicted intracellular proteins Evidence at protein level HPA018856 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 25.4 Expressed in all +LTBP4 FLJ46318, FLJ90018, LTBP-4, LTBP-4L ENSG00000090006 Latent transforming growth factor beta binding protein 4 19 40592883-40629818 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB015194 Approved Ovarian cancer:2.36e-4 (unfavourable) Expressed in all Expressed in all ovary: 244.9 Mixed +BLVRB FLR, SDR43U1 ENSG00000090013 Biliverdin reductase B 19 40447789-40465840 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041698, HPA041937 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:3.90e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 338.3 Cell line enhanced A549: 442.0;K-562: 413.4 +SLC9A1 APNH, NHE1, PPP1R143 ENSG00000090020 Solute carrier family 9 member A1 1 27098815-27166981 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB022371, HPA048532, HPA052891 Enhanced Supported Plasma membrane Glioma:6.32e-4 (unfavourable), Ovarian cancer:7.10e-4 (unfavourable) Expressed in all Expressed in all stomach: 65.5 Expressed in all +SPTLC1 hLCB1, HSAN1, HSN1, LCB1, SPTI ENSG00000090054 Serine palmitoyltransferase long chain base subunit 1 9 92031999-92115384 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA010860, CAB018747, HPA063907 Supported Supported Endoplasmic reticulum Renal cancer:1.36e-6 (favourable) Expressed in all Expressed in all thyroid gland: 108.3 Expressed in all +PAPOLA PAP ENSG00000090060 Poly(A) polymerase alpha 14 96501433-96567111 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001788 Supported Enhanced Nucleoplasm Liver cancer:2.41e-5 (unfavourable) Expressed in all Expressed in all testis: 166.9 Expressed in all +CCNK CPR4 ENSG00000090061 Cyclin K 14 99481169-99535044 Predicted intracellular proteins Evidence at protein level HPA000645, HPA077073 Enhanced Supported Nucleoplasm Expressed in all Expressed in all testis: 84.2 Expressed in all +PCBP4 LIP4, MCG10 ENSG00000090097 Poly(rC) binding protein 4 3 51957454-51974016 Predicted intracellular proteins Evidence at protein level HPA057754 Supported Cytosol Expressed in all Expressed in all cerebral cortex: 113.5 Cell line enhanced SH-SY5Y: 170.4 +RGS1 1R20, BL34, IER1, IR20 ENSG00000090104 Regulator of G-protein signaling 1 1 192575727-192580031 Predicted intracellular proteins Evidence at protein level Renal cancer:4.91e-5 (unfavourable), Stomach cancer:9.57e-4 (unfavourable) Expressed in all Mixed appendix: 225.9 Group enriched 26 Karpas-707: 152.1;U-266/70: 700.2 +YPEL3 MGC10500 ENSG00000090238 Yippee like 3 16 30092314-30096915 Predicted intracellular proteins Evidence at transcript level HPA030501, HPA045621 Uncertain Head and neck cancer:1.09e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 117.0 Mixed +MRPS33 CGI-139 ENSG00000090263 Mitochondrial ribosomal protein S33 7 141002610-141015228 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA030425 Uncertain Expressed in all Expressed in all epididymis: 96.2 Expressed in all +NDUFB2 AGGG, CI-AGGG ENSG00000090266 NADH:ubiquinone oxidoreductase subunit B2 7 140690777-140722790 Predicted intracellular proteins Evidence at protein level HPA051377 Approved Renal cancer:7.60e-7 (favourable) Expressed in all Expressed in all thyroid gland: 497.1 Expressed in all +NUDC NudC ENSG00000090273 Nuclear distribution C, dynein complex regulator 1 26900238-26946862 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027183, HPA028105 Enhanced Enhanced Cytosol Liver cancer:1.21e-6 (unfavourable) Expressed in all Expressed in all fallopian tube: 150.6 Expressed in all +MAEA EMP, GID9 ENSG00000090316 Macrophage erythroblast attacher 4 1289851-1340147 Predicted intracellular proteins Evidence at protein level HPA036886, HPA058185 Approved Enhanced Nucleoplasm Renal cancer:1.90e-4 (favourable), Head and neck cancer:5.34e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 38.1 Expressed in all +ICAM1 BB2, CD54 ENSG00000090339 Intercellular adhesion molecule 1 19 10270835-10286615 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA002126, CAB002142, HPA004877 Enhanced Uncertain Plasma membrane
Cytosol Renal cancer:1.32e-6 (unfavourable), Breast cancer:7.09e-4 (favourable) Expressed in all Expressed in all lung: 255.9 Cell line enhanced Karpas-707: 302.5 +STRN4 PPP2R6C, ZIN ENSG00000090372 Striatin 4 19 46719507-46746994 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043051, HPA043527, HPA056706 Enhanced Approved Cytosol Liver cancer:6.06e-8 (unfavourable), Ovarian cancer:2.98e-4 (unfavourable) Expressed in all Expressed in all testis: 104.8 Expressed in all +IRAK3 IRAK-M ENSG00000090376 Interleukin 1 receptor associated kinase 3 12 66188879-66254622 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043097 Approved Approved Vesicles Renal cancer:6.23e-4 (unfavourable) Mixed Tissue enhanced bone marrow: 51.0 adipose tissue: 19.3 Cell line enhanced HEL: 20.3;HL-60: 24.1;THP-1: 24.3;U-937: 20.5 +LYZ ENSG00000090382 Lysozyme 12 69348341-69354234 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level CAB000055, HPA048284, HPA066182 Enhanced Approved Nucleoplasm
Golgi apparatus
Actin filaments Head and neck cancer:7.45e-4 (favourable) Expressed in all Expressed in all stomach: 9651.4 Group enriched 5 Hep G2: 633.5;THP-1: 321.5;U-937: 404.3 +SI ENSG00000090402 Sucrase-isomaltase 3 164978898-165078495 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA011897 Enhanced Tissue enhanced Group enriched 15 duodenum: 547.3;small intestine: 493.2 rectum: 34.5 Cell line enhanced BEWO: 1.0;CACO-2: 1.3;RPMI-8226: 1.3;SH-SY5Y: 1.2 +MUL1 C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218 ENSG00000090432 Mitochondrial E3 ubiquitin protein ligase 1 1 20499448-20508161 Enzymes, Predicted membrane proteins Evidence at protein level HPA026827 Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:6.15e-14 (favourable) Expressed in all Expressed in all parathyroid gland: 39.7 Expressed in all +TFAP4 AP-4, bHLHc41 ENSG00000090447 Transcription factor AP-4 16 4257186-4273075 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001912 Supported Supported Nucleoplasm
Mitochondria Renal cancer:4.31e-6 (unfavourable), Liver cancer:3.32e-4 (unfavourable) Expressed in all Expressed in all ovary: 12.0 Expressed in all +PDCD7 ES18, HES18 ENSG00000090470 Programmed cell death 7 15 65117379-65133836 Predicted intracellular proteins Evidence at protein level HPA049388 Approved Approved Nucleoli
Plasma membrane Renal cancer:1.00e-4 (unfavourable) Expressed in all Expressed in all testis: 30.7 Expressed in all +SPG21 ACP33, BM-019, GL010, MAST ENSG00000090487 SPG21, maspardin 15 64963021-64990310 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040407, HPA040436 Approved Supported Vesicles
Cytosol Expressed in all Expressed in all epididymis: 182.9 Expressed in all +FETUB ENSG00000090512 Fetuin B 3 186635969-186653141 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035132 Supported Tissue enriched Tissue enriched 16 liver: 123.3 esophagus: 7.6 Not detected +DNAJB11 EDJ, ERdj3, HEDJ ENSG00000090520 DnaJ heat shock protein family (Hsp40) member B11 3 186567403-186585800 Predicted secreted proteins Evidence at protein level HPA010814, HPA017051 Supported Supported Endoplasmic reticulum Renal cancer:3.44e-9 (unfavourable) Expressed in all Expressed in all thyroid gland: 88.4 Expressed in all +P3H2 FLJ10718, LEPREL1, MLAT4 ENSG00000090530 Prolyl 3-hydroxylase 2 3 189956728-190122437 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007890, HPA013355 Approved Expressed in all Mixed prostate: 60.8 Cell line enhanced HaCaT: 97.1;RPTEC TERT1: 83.3 +THPO MGDF, MPLLG, TPO ENSG00000090534 Thrombopoietin 3 184371935-184378144 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Renal cancer:2.48e-6 (unfavourable) Tissue enriched Tissue enhanced liver: 8.9 testis: 3.9 Cell line enhanced CACO-2: 4.9;Hep G2: 10.6;K-562: 2.5;RPMI-8226: 2.8 +CHRD ENSG00000090539 Chordin 3 184380073-184390736 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA035827 Approved Renal cancer:6.09e-7 (unfavourable) Mixed Mixed endometrium: 16.8 Cell line enhanced Hep G2: 7.9;U-2 OS: 4.0 +FLT3LG ENSG00000090554 Fms related tyrosine kinase 3 ligand 19 49474207-49486231 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Cervical cancer:2.17e-5 (favourable) Mixed Mixed lymph node: 27.7 Mixed +RAB11FIP3 eferin, KIAA0665, Rab11-FIP3 ENSG00000090565 RAB11 family interacting protein 3 16 425619-523011 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA028088, HPA028631, HPA030086 Approved Supported Vesicles
Cytokinetic bridge
Microtubule organizing center Pancreatic cancer:3.16e-5 (favourable), Liver cancer:9.87e-5 (unfavourable), Endometrial cancer:1.22e-4 (favourable), Renal cancer:7.99e-4 (favourable) Expressed in all Expressed in all kidney: 56.9 Expressed in all +GNPTG C16orf27, c316G12.3, CAB56184, GNPTAG ENSG00000090581 N-acetylglucosamine-1-phosphate transferase gamma subunit 16 1351923-1364113 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA004055 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all Expressed in all adrenal gland: 66.2 Expressed in all +ZNF268 HZF3 ENSG00000090612 Zinc finger protein 268 12 133181409-133214831 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001794 Approved Approved Actin filaments
Cytosol Expressed in all Mixed parathyroid gland: 23.5 Mixed +GOLGA3 GCP170, golgin-160, MEA-2 ENSG00000090615 Golgin A3 12 132768909-132828858 Predicted intracellular proteins Evidence at protein level HPA039809, HPA040044 Enhanced Supported Nucleus
Golgi apparatus Renal cancer:6.47e-5 (unfavourable), Liver cancer:2.73e-4 (unfavourable), Pancreatic cancer:3.87e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 18.5 Expressed in all +PABPC4 APP-1, iPABP ENSG00000090621 Poly(A) binding protein cytoplasmic 4 1 39560816-39576790 Predicted intracellular proteins Evidence at protein level HPA027301, HPA056496 Approved Enhanced Cytosol Renal cancer:3.00e-10 (unfavourable), Liver cancer:1.14e-7 (unfavourable) Expressed in all Expressed in all skeletal muscle: 206.3 Expressed in all +CD209 CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1 ENSG00000090659 CD209 molecule 19 7739994-7747564 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB032436, CAB033831 Supported Renal cancer:1.15e-5 (unfavourable) Mixed Tissue enhanced adipose tissue: 43.9 placenta: 33.0 Cell line enriched 9 THP-1: 2.3 +CERS4 FLJ12089, LASS4, Trh1 ENSG00000090661 Ceramide synthase 4 19 8206736-8262421 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB033734, HPA054729 Uncertain Approved Nucleus
Vesicles Lung cancer:3.45e-5 (favourable), Renal cancer:9.63e-5 (favourable), Cervical cancer:2.71e-4 (favourable), Head and neck cancer:7.83e-4 (favourable), Pancreatic cancer:8.05e-4 (favourable) Expressed in all Mixed thyroid gland: 80.8 Cell line enhanced NB-4: 63.0 +MCOLN1 ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1 ENSG00000090674 Mucolipin 1 19 7522626-7534009 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA031763, CAB032637 Uncertain Supported Plasma membrane
Cytosol Pancreatic cancer:5.60e-5 (favourable), Renal cancer:5.67e-4 (favourable) Expressed in all Expressed in all spleen: 48.2 Expressed in all +USP48 FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31 ENSG00000090686 Ubiquitin specific peptidase 48 1 21678298-21783606 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030045, HPA030046 Approved Approved Supported Nucleoplasm
Mitochondria
Cytosol Liver cancer:6.09e-8 (unfavourable) Expressed in all Expressed in all adrenal gland: 54.0 Expressed in all +EFNB1 CFNS, Elk-L, EPLG2, LERK2 ENSG00000090776 Ephrin B1 X 68828997-68842147 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB031489, HPA067188 Uncertain Supported Plasma membrane Endometrial cancer:3.32e-5 (unfavourable), Pancreatic cancer:4.29e-4 (unfavourable), Melanoma:8.68e-4 (unfavourable) Expressed in all Mixed adipose tissue: 37.8 Mixed +PDPR PDP3 ENSG00000090857 Pyruvate dehydrogenase phosphatase regulatory subunit 16 70113626-70162537 Predicted intracellular proteins Evidence at protein level HPA048092, HPA070386 Uncertain Approved Mitochondria Renal cancer:8.36e-4 (favourable) Expressed in all Expressed in all testis: 29.0 Expressed in all +AARS AlaRS, CMT2N ENSG00000090861 Alanyl-tRNA synthetase 16 70252295-70289543 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB034261, HPA040870, HPA044223 Supported Enhanced Cytosol Expressed in all Expressed in all parathyroid gland: 178.0 Expressed in all +GLG1 CFR-1, ESL-1, MG-160 ENSG00000090863 Golgi glycoprotein 1 16 74447427-74607144 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010815 Supported Enhanced Golgi apparatus Renal cancer:1.56e-7 (favourable), Cervical cancer:1.99e-4 (unfavourable), Urothelial cancer:7.97e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 167.1 Expressed in all +KIF4A FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100 ENSG00000090889 Kinesin family member 4A X 70290090-70420832 Predicted intracellular proteins Evidence at protein level HPA034745, HPA034746, HPA061583 Approved Enhanced Nucleoplasm
Cytokinetic bridge Liver cancer:7.37e-6 (unfavourable), Pancreatic cancer:9.44e-6 (unfavourable) Mixed Mixed bone marrow: 7.0 Mixed +TNRC6A CAGH26, GW182, KIAA1460, TNRC6 ENSG00000090905 Trinucleotide repeat containing 6A 16 24610209-24827632 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015305, HPA017869 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all Expressed in all parathyroid gland: 68.2 Expressed in all +PLEKHG2 ARHGEF42, CLG, FLJ00018 ENSG00000090924 Pleckstrin homology and RhoGEF domain containing G2 19 39412585-39428415 Predicted intracellular proteins Evidence at protein level HPA017973, HPA048054 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.79e-8 (unfavourable), Colorectal cancer:3.53e-4 (unfavourable) Expressed in all Expressed in all placenta: 33.2 Expressed in all +DLL3 SCDO1 ENSG00000090932 Delta like canonical Notch ligand 3 19 39498895-39508481 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA056533 Approved Nucleoplasm
Cytosol Endometrial cancer:2.94e-4 (unfavourable) Group enriched Tissue enriched 49 cerebral cortex: 51.3 testis: 1.0 Group enriched 6 SCLC-21H: 16.1;SH-SY5Y: 14.9;SK-MEL-30: 62.1 +NAT14 KLP1 ENSG00000090971 N-acetyltransferase 14 (putative) 19 55485004-55487568 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047187 Approved Mitochondria Renal cancer:3.61e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 26.7 Expressed in all +PITPNM2 NIR3, RDGB2, RDGBA2 ENSG00000090975 Phosphatidylinositol transfer protein membrane associated 2 12 122983480-123150015 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003414, HPA003978 Approved Supported Vesicles Expressed in all Mixed ovary: 19.1 Cell line enhanced HEL: 26.5;MOLT-4: 44.3 +EXOC1 BM-102, FLJ10893, SEC3, SEC3L1, Sec3p ENSG00000090989 Exocyst complex component 1 4 55853616-55905034 Predicted intracellular proteins, Transporters Evidence at protein level HPA037706, HPA044873 Uncertain Approved Plasma membrane
Microtubules
Cytosol Urothelial cancer:5.50e-5 (favourable), Liver cancer:2.63e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 39.7 Expressed in all +RBM27 ARRS1, KIAA1311, Psc1, ZC3H20 ENSG00000091009 RNA binding motif protein 27 5 146203600-146289132 Predicted intracellular proteins Evidence at protein level HPA035944, HPA036422 Approved Approved Nuclear speckles Liver cancer:8.58e-4 (unfavourable) Expressed in all Expressed in all testis: 19.0 Expressed in all +POU4F3 BRN3C, DFNA15, DFNA42, DFNA52 ENSG00000091010 POU class 4 homeobox 3 5 146339024-146340520 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038215 Uncertain Supported Nucleoplasm Tissue enhanced Not detected all non-specific tissues: 0.0 Not detected +OSBPL8 MST120, MSTP120, ORP8, OSBP10 ENSG00000091039 Oxysterol binding protein like 8 12 76351797-76559809 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA001309 Uncertain Approved Vesicles
Cytosol Pancreatic cancer:9.79e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.5 Expressed in all +DTX2 KIAA1528, RNF58 ENSG00000091073 Deltex E3 ubiquitin ligase 2 7 76461676-76505995 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042931 Approved Supported Nucleoplasm
Nuclear membrane Renal cancer:1.13e-8 (unfavourable), Glioma:7.25e-4 (unfavourable) Expressed in all Expressed in all esophagus: 37.2 Expressed in all +NLRC4 CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf ENSG00000091106 NLR family CARD domain containing 4 2 32224453-32265854 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006592 Uncertain Mixed Tissue enhanced appendix: 12.4 lung: 9.3 Cell line enhanced HL-60: 2.4 +PUS7 FLJ20485 ENSG00000091127 Pseudouridylate synthase 7 (putative) 7 105439661-105522267 Predicted intracellular proteins Evidence at protein level HPA024116 Approved Approved Nucleus Renal cancer:1.03e-8 (unfavourable), Liver cancer:4.89e-6 (unfavourable), Melanoma:7.58e-5 (unfavourable), Thyroid cancer:6.28e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 15.0 Expressed in all +LAMB4 ENSG00000091128 Laminin subunit beta 4 7 108023548-108130356 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020242, HPA024247 Approved Uncertain Cytosol Tissue enhanced Tissue enriched 12 skin: 46.5 placenta: 3.8 Cell line enhanced BEWO: 1.8 +NRCAM Bravo, KIAA0343 ENSG00000091129 Neuronal cell adhesion molecule 7 108147623-108456717 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012606 Approved Tissue enriched Tissue enhanced cerebral cortex: 180.4 adrenal gland: 49.5 Cell line enhanced A549: 90.2;AF22: 93.7;EFO-21: 165.3;HMC-1: 165.2;SH-SY5Y: 122.8 +LAMB1 CLM ENSG00000091136 Laminin subunit beta 1 7 107923799-108003255 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004056, HPA004132, CAB004256 Enhanced Liver cancer:2.07e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 263.7 adipose tissue: 161.4 Cell line enhanced HSkMC: 640.2 +SLC26A4 DFNB4, PDS ENSG00000091137 Solute carrier family 26 member 4 7 107660635-107717809 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA042860 Approved Tissue enriched Tissue enriched 28 thyroid gland: 419.0 cerebral cortex: 15.1 Cell line enhanced LHCN-M2: 3.7;SCLC-21H: 1.9 +SLC26A3 CLD, DRA ENSG00000091138 Solute carrier family 26 member 3 7 107765467-107803225 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA036055 Approved Tissue enriched Tissue enhanced colon: 1075.0;duodenum: 577.9;rectum: 961.7 seminal vesicle: 185.8 Cell line enhanced RPMI-8226: 1.9 +DLD DLDH, GCSL, LAD ENSG00000091140 Dihydrolipoamide dehydrogenase 7 107890970-107931730 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA044849 Enhanced Supported Mitochondria Renal cancer:7.58e-9 (favourable) Expressed in all Expressed in all heart muscle: 174.7 Expressed in all +WDR7 KIAA0541, TRAG ENSG00000091157 WD repeat domain 7 18 56651343-57036606 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042074, HPA051057 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.13e-5 (favourable) Expressed in all Tissue enhanced cerebral cortex: 38.6 parathyroid gland: 17.0 Expressed in all +TXNL1 TRP32, Txl, TXNL ENSG00000091164 Thioredoxin like 1 18 56597208-56651600 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002828, HPA002829, CAB016446 Supported Supported Enhanced Cytosol Liver cancer:9.62e-6 (unfavourable), Ovarian cancer:6.26e-5 (favourable) Expressed in all Expressed in all thyroid gland: 334.3 Expressed in all +IL5RA CD125, CDw125, IL5R ENSG00000091181 Interleukin 5 receptor subunit alpha 3 3066326-3126613 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced fallopian tube: 22.7 lung: 4.9 Cell line enriched 28 HMC-1: 66.2 +ABCC6 ARA, EST349056, MLP1, MRP6, PXE, URG7 ENSG00000091262 ATP binding cassette subfamily C member 6 16 16148928-16223522 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA038105 Supported Plasma membrane Liver cancer:3.82e-4 (favourable) Tissue enhanced Tissue enhanced kidney: 16.9;liver: 23.4 duodenum: 13.0 Cell line enriched 6 Hep G2: 45.5 +CMTM6 CKLFSF6, FLJ20396 ENSG00000091317 CKLF like MARVEL transmembrane domain containing 6 3 32481312-32503408 Predicted membrane proteins Evidence at protein level HPA026980 Approved Expressed in all Expressed in all fallopian tube: 238.0 Expressed in all +ITGA6 CD49f ENSG00000091409 Integrin subunit alpha 6 2 172427354-172506282 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB009009, HPA012696, HPA027582 Enhanced Renal cancer:2.35e-11 (favourable), Head and neck cancer:1.03e-4 (unfavourable) Expressed in all Expressed in all placenta: 114.9 Cell line enhanced HaCaT: 319.9;HBEC3-KT: 511.4 +RAPGEF4 cAMP-GEFII, CGEF2 ENSG00000091428 Rap guanine nucleotide exchange factor 4 2 172735274-173052893 Predicted intracellular proteins Evidence at protein level CAB004388, HPA028968 Approved Approved Focal adhesion sites Pancreatic cancer:1.32e-4 (favourable) Mixed Tissue enhanced adrenal gland: 53.3;cerebral cortex: 119.2 liver: 18.3 Cell line enhanced Karpas-707: 15.5;SCLC-21H: 9.8;U-266/70: 8.4;U-266/84: 16.0 +MAP3K20 MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK ENSG00000091436 Mitogen-activated protein kinase kinase kinase 20 2 173075435-173268010 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017205 Approved Supported Cytosol Renal cancer:3.41e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 133.3 Mixed +SMPX DFN6, DFNX4 ENSG00000091482 Small muscle protein, X-linked X 21705972-21758163 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA077360 Approved Plasma membrane Head and neck cancer:3.04e-5 (unfavourable) Tissue enhanced Group enriched 22 heart muscle: 456.2;skeletal muscle: 383.1 esophagus: 19.4 Cell line enhanced CACO-2: 1.2;Hep G2: 2.7;HSkMC: 3.0;Karpas-707: 2.2;U-266/70: 3.3;U-266/84: 1.2 +FH fumarase ENSG00000091483 Fumarate hydratase 1 241497603-241519761 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB017785, HPA025770, HPA025948, HPA027341 Enhanced Approved Enhanced Mitochondria Renal cancer:2.76e-7 (favourable) Expressed in all Expressed in all liver: 142.2 Expressed in all +SEL1L3 KIAA0746 ENSG00000091490 SEL1L family member 3 4 25747427-25863760 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040045, HPA058792 Approved Enhanced Nucleus Urothelial cancer:4.33e-4 (favourable) Expressed in all Expressed in all lymph node: 146.6 Cell line enhanced Daudi: 205.7 +TF PRO1557, PRO2086 ENSG00000091513 Transferrin 3 133745956-133779006 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001527, HPA005692, CAB009538 Enhanced Uncertain Mitochondria Renal cancer:2.35e-13 (unfavourable), Breast cancer:4.05e-4 (favourable) Tissue enriched Tissue enriched 14 liver: 5391.9 cerebral cortex: 385.9 Cell line enriched 50 Hep G2: 842.8 +CDV3 H41 ENSG00000091527 CDV3 homolog 3 133573730-133590261 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029761, HPA029762, HPA029763 Enhanced Enhanced Nucleoli
Plasma membrane
Cytosol Liver cancer:5.21e-6 (unfavourable) Expressed in all Expressed in all lymph node: 185.6 Expressed in all +MYO15A DFNB3, MYO15 ENSG00000091536 Myosin XVA 17 18108706-18179802 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA078501 Supported Not detected Tissue enhanced testis: 10.4 ovary: 2.5 Not detected +ALKBH5 FLJ20308, OFOXD1 ENSG00000091542 AlkB homolog 5, RNA demethylase 17 18183078-18209954 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007196 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Pancreatic cancer:3.75e-4 (favourable), Urothelial cancer:5.69e-4 (unfavourable) Expressed in all Expressed in all testis: 109.7 Expressed in all +APOH B2G1, BG ENSG00000091583 Apolipoprotein H 17 66212033-66256525 Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001654, HPA003732, CAB022214 Enhanced Supported Golgi apparatus Liver cancer:2.39e-7 (favourable), Renal cancer:1.10e-6 (unfavourable) Tissue enriched Tissue enriched 278 liver: 9090.4 kidney: 32.7 Cell line enriched 17 Hep G2: 846.7 +NLRP1 CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1 ENSG00000091592 NLR family pyrin domain containing 1 17 5499427-5619424 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009189, HPA064431 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:1.60e-5 (unfavourable), Pancreatic cancer:7.57e-4 (favourable) Expressed in all Mixed skin: 62.6 Cell line enhanced HDLM-2: 53.6;Karpas-707: 70.7;U-266/70: 37.1 +PITPNM3 ACKR6, CORD5, NIR1, RDGBA3 ENSG00000091622 PITPNM family member 3 17 6451264-6556494 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA022432, HPA059005 Enhanced Approved Plasma membrane Head and neck cancer:3.67e-6 (favourable) Mixed Tissue enhanced spleen: 76.8 ovary: 33.7 Cell line enhanced HaCaT: 15.7;hTCEpi: 36.7 +SPAG7 ACRP, FSA-1, MGC20134 ENSG00000091640 Sperm associated antigen 7 17 4959226-4967872 Predicted intracellular proteins Evidence at protein level HPA024032, HPA052394 Uncertain Supported Nucleus Renal cancer:5.79e-5 (favourable) Expressed in all Expressed in all fallopian tube: 102.8 Expressed in all +ORC6 ORC6L ENSG00000091651 Origin recognition complex subunit 6 16 46689643-46698394 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016330, HPA072587 Enhanced Approved Nucleus
Nucleoli fibrillar center Ovarian cancer:1.48e-4 (favourable), Melanoma:3.53e-4 (unfavourable) Mixed Tissue enhanced testis: 12.3 lymph node: 8.8 Expressed in all +ZFHX4 FLJ20980, ZFH4 ENSG00000091656 Zinc finger homeobox 4 8 76681219-76867285 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023837 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center Mixed Tissue enhanced seminal vesicle: 8.0;testis: 12.1 cerebral cortex: 5.0 Cell line enhanced TIME: 35.2 +SLC17A6 DNPI, VGLUT2 ENSG00000091664 Solute carrier family 17 member 6 11 22338097-22379503 Predicted membrane proteins, Transporters Evidence at protein level CAB037130, HPA039226, CAB078204 Enhanced Supported Not detected Tissue enriched 65 cerebral cortex: 6.5 all non-specific tissues: 0.0 Cell line enriched 263 SCLC-21H: 35.7 +CPA1 CPA ENSG00000091704 Carboxypeptidase A1 7 130380339-130388114 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021836, CAB025197, HPA052215 Enhanced Tissue enriched Tissue enriched 367 pancreas: 48856.8 ovary: 133.1 Cell line enhanced AN3-CA: 10.9;SCLC-21H: 2.5;U-2 OS: 1.7 +ZC3HC1 NIPA ENSG00000091732 Zinc finger C3HC-type containing 1 7 130018286-130051451 Predicted intracellular proteins Evidence at protein level HPA019089, HPA024023 Enhanced Supported Nucleus
Nuclear membrane Liver cancer:1.02e-6 (unfavourable), Endometrial cancer:3.36e-4 (unfavourable) Expressed in all Expressed in all testis: 26.5 Expressed in all +ESR1 Era, ESR, NR3A1 ENSG00000091831 Estrogen receptor 1 6 151656691-152129619 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000037, HPA000449, HPA000450, CAB055099, CAB072858 Enhanced Approved Nucleus
Vesicles Endometrial cancer:5.47e-7 (favourable) Group enriched Group enriched 8 breast: 37.6;cervix, uterine: 127.8;endometrium: 180.8;fallopian tube: 106.4;smooth muscle: 76.5 seminal vesicle: 13.5 Group enriched 11 MCF7: 34.7;T-47d: 53.2 +RGS17 RGS-17, RGSZ2 ENSG00000091844 Regulator of G-protein signaling 17 6 153004459-153131249 Predicted intracellular proteins Evidence at protein level HPA022276, HPA056493 Approved Approved Vesicles Mixed Mixed cerebral cortex: 5.5 Cell line enhanced hTERT-HME1: 13.2;LHCN-M2: 14.6;U-87 MG: 14.3 +ANGPT2 Ang2 ENSG00000091879 Angiopoietin 2 8 6499651-6563409 Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB011437, CAB017626 Approved Renal cancer:1.52e-7 (unfavourable), Liver cancer:6.36e-5 (unfavourable), Cervical cancer:7.99e-5 (unfavourable), Stomach cancer:3.87e-4 (unfavourable), Melanoma:4.48e-4 (unfavourable) Expressed in all Mixed placenta: 19.6 Group enriched 7 HMC-1: 17.8;HSkMC: 34.2;HUVEC TERT2: 62.9;WM-115: 24.3 +TMEM101 FLJ23987, MGC4251 ENSG00000091947 Transmembrane protein 101 17 44011188-44023946 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039739 Approved Nucleoplasm
Plasma membrane Renal cancer:4.10e-5 (favourable), Endometrial cancer:4.29e-4 (favourable), Liver cancer:7.10e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 158.8 Mixed +CD200 MOX1, MOX2, MRC, OX-2 ENSG00000091972 CD200 molecule 3 112332347-112362812 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA031149 Approved Expressed in all Mixed cerebral cortex: 78.6 Cell line enhanced AF22: 74.9;NTERA-2: 47.6;REH: 38.6;WM-115: 82.4 +CCDC80 DRO1, SSG1, URB ENSG00000091986 Coiled-coil domain containing 80 3 112596794-112649530 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002266 Approved Renal cancer:2.86e-5 (unfavourable), Urothelial cancer:1.26e-4 (unfavourable) Expressed in all Mixed smooth muscle: 526.0 Cell line enhanced fHDF/TERT166: 992.9 +CMA1 ENSG00000092009 Chymase 1 14 24505353-24508265 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000363, HPA052634 Enhanced Mixed Tissue enhanced breast: 23.8 esophagus: 11.4 Not detected +PSME1 IFI5111, PA28alpha ENSG00000092010 Proteasome activator subunit 1 14 24136158-24138967 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006632 Approved Breast cancer:8.87e-5 (favourable), Thyroid cancer:4.60e-4 (favourable) Expressed in all Expressed in all lymph node: 329.6 Expressed in all +PPP2R3C C14orf10, FLJ20644, G4-1, G5PR ENSG00000092020 Protein phosphatase 2 regulatory subunit B''gamma 14 35085467-35122517 Predicted intracellular proteins Evidence at protein level HPA040835, HPA058834 Approved Approved Nucleus
Golgi apparatus Expressed in all Expressed in all testis: 98.1 Expressed in all +HAUS4 C14orf94, FLJ20424 ENSG00000092036 HAUS augmin like complex subunit 4 14 22946228-22957161 Predicted intracellular proteins Evidence at protein level HPA029803, HPA071195 Approved Supported Plasma membrane
Focal adhesion sites Urothelial cancer:2.24e-4 (unfavourable) Expressed in all Expressed in all ovary: 61.9 Expressed in all +JPH4 JPHL1, KIAA1831 ENSG00000092051 Junctophilin 4 14 23568035-23578800 Predicted membrane proteins Evidence at transcript level CAB013492 Uncertain Nucleoplasm
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 107.1;seminal vesicle: 51.9 endometrium: 28.1 Group enriched 7 SCLC-21H: 16.8;SH-SY5Y: 37.5;U-2 OS: 27.7 +MYH7 CMD1S, CMH1, MPD1 ENSG00000092054 Myosin heavy chain 7 14 23412738-23435718 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001239, HPA001349, CAB015384 Enhanced Group enriched Group enriched 27 heart muscle: 2309.1;skeletal muscle: 5111.1 esophagus: 135.7 Cell line enriched 23 HSkMC: 8.2 +CEBPE CRP1 ENSG00000092067 CCAAT/enhancer binding protein epsilon 14 23117304-23119616 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002928, CAB005113 Enhanced Enhanced Nucleoplasm Not detected Tissue enriched 9 bone marrow: 26.0 small intestine: 2.7 Cell line enhanced HL-60: 143.2;HMC-1: 26.7;NB-4: 58.7 +SLC7A8 LAT2, LPI-PC1 ENSG00000092068 Solute carrier family 7 member 8 14 23125295-23183674 Predicted membrane proteins, Transporters Evidence at protein level CAB046015, HPA051950, HPA060672 Enhanced Urothelial cancer:1.52e-4 (unfavourable), Liver cancer:1.97e-4 (unfavourable), Lung cancer:3.15e-4 (favourable) Expressed in all Tissue enriched 8 parathyroid gland: 1094.9 kidney: 135.4 Cell line enhanced BEWO: 118.7;K-562: 122.1 +OSGEP GCPL1, KAE1, OSGEP1, PRSMG1 ENSG00000092094 O-sialoglycoprotein endopeptidase 14 20446411-20455105 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039751 Uncertain Supported Nucleoplasm
Plasma membrane Renal cancer:4.64e-6 (unfavourable), Breast cancer:1.48e-4 (favourable) Expressed in all Mixed thyroid gland: 12.7 Expressed in all +SLC22A17 BOCT, BOIT, NGALR ENSG00000092096 Solute carrier family 22 member 17 14 23346306-23352912 Predicted membrane proteins, Transporters Evidence at protein level HPA002728 Uncertain Pancreatic cancer:1.73e-4 (favourable), Stomach cancer:5.95e-4 (unfavourable) Expressed in all Tissue enriched 5 cerebral cortex: 275.0 prostate: 52.6 Cell line enhanced AN3-CA: 35.6;SH-SY5Y: 46.8 +RNF31 FLJ10111, FLJ23501, HOIP, ZIBRA ENSG00000092098 Ring finger protein 31 14 24146683-24160661 Enzymes, Predicted intracellular proteins Evidence at protein level CAB009063, HPA048745 Approved Approved Cytosol Expressed in all Expressed in all skin: 44.4 Expressed in all +SCFD1 C14orf163, KIAA0917, RA410, SLY1, STXBP1L2 ENSG00000092108 Sec1 family domain containing 1 14 30622112-30735812 Predicted intracellular proteins Evidence at protein level HPA003579 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 73.1 Expressed in all +G2E3 FLJ20333, KIAA1333, PHF7B ENSG00000092140 G2/M-phase specific E3 ubiquitin protein ligase 14 30559123-30620063 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001601 Approved Supported Vesicles
Cytosol Expressed in all Tissue enriched 6 testis: 80.4 thyroid gland: 12.9 Mixed +HECTD1 KIAA1131 ENSG00000092148 HECT domain E3 ubiquitin protein ligase 1 14 31100112-31207804 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002929, HPA054461 Approved Supported Nucleus
Nucleoli Renal cancer:1.20e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 109.5 Expressed in all +HNRNPC hnRNPC, HNRPC ENSG00000092199 Heterogeneous nuclear ribonucleoprotein C (C1/C2) 14 21209136-21269494 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005223, HPA051075, CAB075755, CAB075756 Supported Enhanced Nucleoplasm Renal cancer:7.29e-5 (unfavourable), Liver cancer:7.72e-5 (unfavourable), Ovarian cancer:1.19e-4 (favourable) Expressed in all Expressed in all lymph node: 568.9 Expressed in all +RPGRIP1 CORD13, LCA6, RGI1, RPGRIP ENSG00000092200 Retinitis pigmentosa GTPase regulator interacting protein 1 14 21287939-21351301 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042955, HPA060190 Enhanced Tissue enhanced Tissue enriched 48 testis: 105.9 spleen: 2.1 Cell line enhanced RT4: 3.1 +SUPT16H CDC68, FACT, FACTP140, FLJ10857, FLJ14010, SPT16/CDC68 ENSG00000092201 SPT16 homolog, facilitates chromatin remodeling subunit 14 21351472-21384266 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022551, HPA049787 Enhanced Supported Nucleus
Nucleoli fibrillar center Expressed in all Expressed in all parathyroid gland: 95.7 Expressed in all +TOX4 C14orf92, KIAA0737, LCP1 ENSG00000092203 TOX high mobility group box family member 4 14 21476597-21499175 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA017880, HPA027551 Approved Approved Nucleus
Nucleoli
Vesicles Renal cancer:8.38e-5 (favourable), Liver cancer:3.46e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.4 Expressed in all +GEMIN2 SIP1 ENSG00000092208 Gem nuclear organelle associated protein 2 14 39114223-39136973 Predicted intracellular proteins Evidence at protein level CAB015426, HPA046570, HPA057114 Enhanced Supported Nucleus
Nucleoli
Nuclear bodies Liver cancer:3.88e-6 (unfavourable) Expressed in all Expressed in all testis: 17.1 Expressed in all +TGM1 ICR2, LI, LI1, TGASE, TGK ENSG00000092295 Transglutaminase 1 14 24249114-24264432 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB015159, HPA040171 Enhanced Tissue enhanced Tissue enriched 12 esophagus: 831.8 tonsil: 72.2 Cell line enhanced BEWO: 33.0;HaCaT: 42.3;MCF7: 27.0;SK-BR-3: 31.6 +TINF2 TIN2 ENSG00000092330 TERF1 interacting nuclear factor 2 14 24239643-24242674 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059061, HPA069807 Enhanced Nuclear bodies Breast cancer:4.96e-4 (favourable) Expressed in all Tissue enriched 24 parathyroid gland: 1349.0 smooth muscle: 56.5 Expressed in all +DAZL DAZH, DAZL1, DAZLA, MGC26406, SPGYLA ENSG00000092345 Deleted in azoospermia like 3 16586792-16670306 Predicted intracellular proteins Evidence at protein level HPA019593, HPA019777, HPA047113 Enhanced Tissue enriched Tissue enriched 153 testis: 141.6 tonsil: 0.9 Cell line enriched 9 HAP1: 20.2 +TBL1Y TBL1 ENSG00000092377 Transducin beta like 1, Y-linked Y 6910686-7091683 Predicted intracellular proteins Evidence at protein level HPA060073 Uncertain Tissue enriched Tissue enhanced prostate: 2.6;thyroid gland: 1.4 testis: 0.5 Cell line enhanced BEWO: 1.5;NTERA-2: 1.3;RT4: 1.2;SCLC-21H: 1.1;U-698: 6.6 +SEMA6A HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ ENSG00000092421 Semaphorin 6A 5 116443616-116574934 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA031265, HPA031267 Approved Supported Nucleus
Intermediate filaments Liver cancer:4.39e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 49.1 Cell line enhanced AF22: 36.5;AN3-CA: 41.0;BEWO: 36.9;HAP1: 53.6;NTERA-2: 115.0 +TRPM7 CHAK1, LTRPC7, TRP-PLIK ENSG00000092439 Transient receptor potential cation channel subfamily M member 7 15 50552473-50686815 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA052173 Enhanced Approved Nucleoplasm Expressed in all Tissue enriched 7 parathyroid gland: 216.4 thyroid gland: 29.0 Expressed in all +TYRO3 Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif ENSG00000092445 TYRO3 protein tyrosine kinase 15 41557675-41583586 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA071245 Approved Expressed in all Tissue enhanced cerebral cortex: 67.4;ovary: 61.6 testis: 37.0 Cell line enhanced BEWO: 66.6 +WDR76 FLJ12973 ENSG00000092470 WD repeat domain 76 15 43826963-43868419 Predicted intracellular proteins Evidence at protein level HPA039804, HPA040626 Uncertain Approved Nucleoli fibrillar center
Nuclear bodies Renal cancer:1.35e-8 (unfavourable), Lung cancer:8.02e-5 (unfavourable), Pancreatic cancer:5.02e-4 (unfavourable), Liver cancer:6.98e-4 (unfavourable) Expressed in all Mixed lymph node: 23.7 Expressed in all +CAPN3 CANP3, LGMD2, LGMD2A, nCL-1, p94 ENSG00000092529 Calpain 3 15 42359500-42412318 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA040052 Enhanced Tissue enriched Tissue enhanced epididymis: 217.3;skeletal muscle: 336.8 skin: 92.9 Cell line enriched 27 SK-MEL-30: 202.7 +SNAP23 HsT17016, SNAP23A, SNAP23B ENSG00000092531 Synaptosome associated protein 23 15 42491233-42545356 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA001214, CAB037083, CAB037317 Approved Supported Plasma membrane Expressed in all Expressed in all spleen: 86.7 Expressed in all +TBX15 TBX14 ENSG00000092607 T-box 15 1 118883046-118989556 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052245, HPA053713 Uncertain Approved Nucleoplasm
Centrosome Renal cancer:5.57e-8 (unfavourable) Mixed Group enriched 7 adipose tissue: 17.0;breast: 8.9;liver: 24.1;skeletal muscle: 42.2 lymph node: 3.1 Cell line enhanced ASC diff: 36.8;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;fHDF/TERT166: 22.5;HSkMC: 28.3;RH-30: 29.4;U-2197: 26.3 +PHGDH PDG, PGDH, SERA ENSG00000092621 Phosphoglycerate dehydrogenase 1 119659798-119744215 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003681, HPA021241, HPA024031, CAB068216 Enhanced Enhanced Nucleoplasm
Plasma membrane
Cytosol Endometrial cancer:1.48e-4 (unfavourable), Glioma:2.26e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 216.7 skin: 115.9 Mixed +COL9A3 DJ885L7.4.1, EDM3, FLJ90759, IDD, MED ENSG00000092758 Collagen type IX alpha 3 chain 20 62816244-62841159 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040125, HPA058323 Supported Approved Nucleoplasm
Intermediate filaments Mixed Group enriched 6 cerebral cortex: 7.5;salivary gland: 10.5;testis: 6.3;thyroid gland: 19.1 seminal vesicle: 1.8 Group enriched 6 BEWO: 139.2;Hep G2: 40.1;SK-MEL-30: 37.9;WM-115: 57.3 +EZR VIL2 ENSG00000092820 Ezrin 6 158765741-158819412 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004035, HPA021616, CAB047324, CAB075739 Enhanced Enhanced Plasma membrane Renal cancer:9.56e-8 (favourable), Pancreatic cancer:1.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 537.0 Expressed in all +MYL6 ESMLC, MLC1SM, MLC3NM ENSG00000092841 Myosin light chain 6 12 56158161-56163496 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046859, HPA063034 Approved Expressed in all Expressed in all smooth muscle: 5966.7 Expressed in all +AGO1 EIF2C1, hAGO1 ENSG00000092847 Argonaute 1, RISC catalytic component 1 35869808-35930528 Predicted intracellular proteins Evidence at protein level Liver cancer:4.57e-5 (unfavourable), Renal cancer:2.60e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 16.0 Expressed in all +TEKT2 TEKTB1 ENSG00000092850 Tektin 2 1 36084075-36088275 Predicted intracellular proteins Evidence at protein level HPA027248, HPA027461 Approved Uncertain Microtubules Renal cancer:1.98e-4 (favourable) Tissue enhanced Group enriched 9 fallopian tube: 97.8;testis: 63.3 lung: 8.8 Cell line enriched 5 NB-4: 23.2 +CLSPN ENSG00000092853 Claspin 1 35720218-35769967 Predicted intracellular proteins Evidence at protein level HPA026305, HPA026312 Enhanced Nucleoplasm
Golgi apparatus Stomach cancer:4.92e-4 (favourable) Mixed Tissue enhanced testis: 10.6 bone marrow: 7.0 Mixed +RFFL CARP-2, CARP2, fring, rififylin, RNF189, RNF34L ENSG00000092871 Ring finger and FYVE like domain containing E3 ubiquitin protein ligase 17 35005990-35089319 Enzymes, Predicted intracellular proteins Evidence at protein level CAB008096, HPA017910, HPA019492 Approved Approved Vesicles Renal cancer:2.43e-5 (unfavourable), Colorectal cancer:4.92e-4 (favourable) Expressed in all Expressed in all thyroid gland: 54.1 Expressed in all +UNC13D Munc13-4 ENSG00000092929 Unc-13 homolog D 17 75827225-75844717 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA067117, HPA073525 Enhanced Supported Vesicles
Cytosol Renal cancer:5.28e-12 (unfavourable), Endometrial cancer:3.62e-4 (unfavourable), Pancreatic cancer:6.01e-4 (unfavourable) Expressed in all Mixed spleen: 38.6 Cell line enhanced HEL: 219.6;HMC-1: 213.8;SK-BR-3: 125.9 +MFSD11 FLJ20226, FLJ22196 ENSG00000092931 Major facilitator superfamily domain containing 11 17 76735865-76781449 Predicted membrane proteins Evidence at protein level HPA022001 Uncertain Approved Nuclear speckles Endometrial cancer:7.69e-4 (unfavourable), Urothelial cancer:7.90e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.5 Expressed in all +DPYSL2 CRMP2, DHPRP2, DRP-2, DRP2 ENSG00000092964 Dihydropyrimidinase like 2 8 26514022-26658178 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002381, CAB018719 Supported Supported Plasma membrane
Cytosol Urothelial cancer:5.41e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 379.1 Mixed +TGFB2 ENSG00000092969 Transforming growth factor beta 2 1 218346235-218444619 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Expressed in all Tissue enhanced prostate: 30.4 placenta: 20.4 Cell line enhanced EFO-21: 58.6;U-2 OS: 64.1 +GPATCH2 CT110, FLJ10252, GPATC2, PPP1R30 ENSG00000092978 G-patch domain containing 2 1 217426992-217631082 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027181, HPA027322 Uncertain Supported Nuclear speckles Renal cancer:9.99e-6 (unfavourable) Expressed in all Mixed parathyroid gland: 11.8 Mixed +NUP50 NPAP60L ENSG00000093000 Nucleoporin 50 22 45163841-45188015 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA047162, HPA048328 Enhanced Enhanced Nucleoplasm
Nuclear membrane Stomach cancer:4.06e-4 (favourable) Expressed in all Expressed in all testis: 54.6 Expressed in all +CDC45 CDC45L, CDC45L2 ENSG00000093009 Cell division cycle 45 22 19479459-19520612 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000614, CAB009459 Enhanced Supported Nucleoplasm
Centrosome
Cytosol Liver cancer:6.95e-6 (unfavourable), Pancreatic cancer:8.94e-4 (unfavourable) Expressed in all Tissue enhanced testis: 37.5 bone marrow: 15.3 Expressed in all +COMT ENSG00000093010 Catechol-O-methyltransferase 22 19941607-19969975 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001169, CAB011233 Enhanced Approved Endoplasmic reticulum
Vesicles Endometrial cancer:3.68e-4 (favourable), Prostate cancer:5.67e-4 (favourable), Renal cancer:9.76e-4 (unfavourable) Expressed in all Expressed in all placenta: 172.6 Expressed in all +CECR1 ADGF, IDGFL ENSG00000093072 Cat eye syndrome chromosome region, candidate 1 22 17178790-17221989 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007888 Approved Pancreatic cancer:8.91e-4 (favourable), Ovarian cancer:9.26e-4 (favourable) Expressed in all Expressed in all spleen: 161.4 Cell line enhanced CAPAN-2: 22.2;Karpas-707: 30.5;MOLT-4: 33.3;U-937: 32.1 +VNN3 HSA238982 ENSG00000093134 Vanin 3 6 132722787-132734765 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enhanced bone marrow: 35.3;liver: 15.2 spleen: 9.5 Not detected +ECHDC1 dJ351K20.2 ENSG00000093144 Ethylmalonyl-CoA decarboxylase 1 6 127288710-127343609 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035445, HPA035446 Uncertain Approved Vesicles Expressed in all Expressed in all adipose tissue: 98.5 Mixed +LRRFIP2 HUFI-2 ENSG00000093167 LRR binding FLII interacting protein 2 3 37052656-37183689 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035956, HPA042023 Uncertain Approved Plasma membrane
Actin filaments Cervical cancer:6.31e-4 (favourable) Expressed in all Expressed in all testis: 130.8 Expressed in all +SEC22C MGC13261, MGC5373, SEC22L3 ENSG00000093183 SEC22 homolog C, vesicle trafficking protein 3 42547969-42601080 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055594 Approved Golgi apparatus Renal cancer:1.35e-7 (favourable), Liver cancer:3.04e-5 (unfavourable) Expressed in all Expressed in all prostate: 63.7 Expressed in all +XYLB FLJ10343, FLJ12539 ENSG00000093217 Xylulokinase 3 38346760-38421348 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037863, HPA038415 Uncertain Approved Nuclear speckles Renal cancer:8.57e-4 (favourable) Mixed Tissue enhanced liver: 15.2 kidney: 9.9 Mixed +HDAC6 FLJ16239, HD6, JM21, KIAA0901, PPP1R90 ENSG00000094631 Histone deacetylase 6 X 48801377-48824982 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA003714, CAB004236, HPA026321 Approved Supported Nucleoplasm Urothelial cancer:3.34e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 51.4 Expressed in all +OR1I1 OR19-20, OR1I1P, OR1I1Q ENSG00000094661 Olfactory receptor family 1 subfamily I member 1 19 15086980-15088221 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +GABRP ENSG00000094755 Gamma-aminobutyric acid type A receptor pi subunit 5 170763350-170814047 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB014883 Uncertain Cervical cancer:3.37e-4 (favourable) Mixed Expressed in all breast: 177.0 Cell line enhanced A-431: 184.7;EFO-21: 182.4;PC-3: 293.8 +KRT31 Ha-1, KRTHA1 ENSG00000094796 Keratin 31 17 41393724-41397592 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049550, HPA055194 Supported Group enriched Group enriched 6 esophagus: 4.6;skin: 14.4 skeletal muscle: 1.5 Not detected +CDC6 CDC18L ENSG00000094804 Cell division cycle 6 17 40287633-40304657 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050114, HPA065070 Approved Supported Nucleus
Cytokinetic bridge
Mitotic spindle
Cytosol Liver cancer:5.96e-8 (unfavourable), Pancreatic cancer:2.90e-4 (unfavourable) Expressed in all Mixed appendix: 15.4 Expressed in all +UPRT DKFZp781E1243, FUR1, MGC23937, RP11-311P8.3 ENSG00000094841 Uracil phosphoribosyltransferase homolog X 75274085-75304600 Predicted intracellular proteins Evidence at protein level HPA000805 Uncertain Approved Vesicles Renal cancer:4.14e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.4 Mixed +CDC23 ANAPC8, APC8, CUT23 ENSG00000094880 Cell division cycle 23 5 138187648-138213343 Predicted secreted proteins Evidence at protein level HPA039593 Approved Liver cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all placenta: 37.3 Expressed in all +AAAS ENSG00000094914 Aladin WD repeat nucleoporin 12 53307456-53324864 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA040086 Approved Approved Nuclear membrane
Centrosome
Cytosol Renal cancer:2.93e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 46.2 Expressed in all +CBX5 HP1, HP1-ALPHA, HP1Hs-alpha ENSG00000094916 Chromobox 5 12 54230940-54280133 Predicted intracellular proteins Evidence at protein level HPA016699, CAB017548 Enhanced Enhanced Nucleus Expressed in all Expressed in all parathyroid gland: 58.2 Expressed in all +FMO2 ENSG00000094963 Flavin containing monooxygenase 2 1 171185208-171211230 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA028261 Approved Mixed Tissue enhanced adipose tissue: 98.3;esophagus: 102.9;lung: 158.2 breast: 55.8 Group enriched 48 ASC diff: 27.9;ASC TERT1: 12.9;HSkMC: 35.2 +SUCO C1orf9, CH1, OPT, SLP1 ENSG00000094975 SUN domain containing ossification factor 1 172532349-172611833 Predicted membrane proteins Evidence at protein level HPA047251 Approved Approved Nucleoli fibrillar center
Cytosol Liver cancer:2.86e-4 (unfavourable) Expressed in all Mixed epididymis: 75.9 Expressed in all +MSH2 COCA1, HNPCC, HNPCC1 ENSG00000095002 MutS homolog 2 2 47402969-47562311 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009572, HPA066845, CAB070867 Supported Supported Nucleoplasm
Vesicles Liver cancer:1.72e-9 (unfavourable), Endometrial cancer:4.44e-4 (unfavourable), Pancreatic cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all testis: 32.2 Expressed in all +MAP3K1 MAPKKK1, MEKK, MEKK1 ENSG00000095015 Mitogen-activated protein kinase kinase kinase 1 5 56815574-56896152 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB004500, HPA046509 Approved Approved Cytosol Expressed in all Mixed spleen: 28.3 Cell line enhanced SH-SY5Y: 55.9 +DHPS MIG13 ENSG00000095059 Deoxyhypusine synthase 19 12675717-12681902 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA014461, HPA029413 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all fallopian tube: 64.5 Expressed in all +HOOK2 HK2 ENSG00000095066 Hook microtubule tethering protein 2 19 12763003-12872740 Predicted intracellular proteins Evidence at protein level HPA043519, HPA050351 Approved Supported Vesicles
Cytosol Prostate cancer:7.59e-5 (unfavourable), Renal cancer:3.28e-4 (favourable) Expressed in all Expressed in all thyroid gland: 96.0 Expressed in all +NXPE1 FAM55A, MGC34290 ENSG00000095110 Neurexophilin and PC-esterase domain family member 1 11 114521715-114559895 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049133 Enhanced Tissue enriched Group enriched 13 colon: 111.8;rectum: 165.9 appendix: 10.5 Not detected +ARCN1 COPD ENSG00000095139 Archain 1 11 118572390-118603033 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037573, HPA044874 Approved Enhanced Golgi apparatus
Vesicles Liver cancer:2.97e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 144.4 Expressed in all +EPB41L4B EHM2 ENSG00000095203 Erythrocyte membrane protein band 4.1 like 4B 9 109171975-109320964 Predicted intracellular proteins Evidence at protein level HPA042862 Approved Approved Plasma membrane
Cytosol Breast cancer:1.02e-4 (unfavourable) Mixed Mixed thyroid gland: 74.8 Cell line enhanced BEWO: 30.5;hTCEpi: 36.0 +TMEM38B bA219P18.1, C9orf87, D4Ertd89e, FLJ10493, TRIC-B ENSG00000095209 Transmembrane protein 38B 9 105694544-105776612 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA018465 Uncertain Renal cancer:7.96e-4 (favourable) Expressed in all Expressed in all testis: 51.9 Expressed in all +PSMD5 KIAA0072, S5B ENSG00000095261 Proteasome 26S subunit, non-ATPase 5 9 120815496-120842984 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003216 Uncertain Approved Nucleus
Cytosol Expressed in all Expressed in all prostate: 28.7 Mixed +PTGS1 COX1, PGHS-1, PTGHS ENSG00000095303 Prostaglandin-endoperoxide synthase 1 9 122370530-122395703 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002834, CAB020315 Enhanced Supported Golgi apparatus
Vesicles Renal cancer:8.68e-4 (unfavourable), Urothelial cancer:9.35e-4 (unfavourable) Expressed in all Tissue enhanced skin: 161.6 fallopian tube: 86.1 Cell line enhanced ASC diff: 104.2;BJ: 149.8;BJ hTERT+: 187.6;HMC-1: 391.6 +NUP188 KIAA0169 ENSG00000095319 Nucleoporin 188 9 128947699-129007096 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA061750, HPA063942 Approved Supported Nucleus Endometrial cancer:5.20e-5 (favourable) Expressed in all Expressed in all testis: 104.6 Expressed in all +CRAT CAT1 ENSG00000095321 Carnitine O-acetyltransferase 9 129094810-129111189 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA019230, HPA020260, HPA022815 Enhanced Approved Nucleoplasm
Nuclear membrane Renal cancer:0.00e+0 (favourable), Endometrial cancer:2.36e-4 (favourable) Expressed in all Expressed in all testis: 116.0 Mixed +SH2D3C NSP3 ENSG00000095370 SH2 domain containing 3C 9 127738317-127778741 Predicted intracellular proteins Evidence at protein level HPA047586 Enhanced Head and neck cancer:1.98e-4 (favourable), Endometrial cancer:9.47e-4 (favourable) Expressed in all Mixed spleen: 49.7 Cell line enhanced HMC-1: 47.3;HUVEC TERT2: 50.2;REH: 55.2;RPMI-8226: 32.1;TIME: 40.8 +NANS SAS ENSG00000095380 N-acetylneuraminate synthase 9 98056739-98083075 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019223 Approved Approved Nucleoplasm Endometrial cancer:1.71e-4 (favourable), Liver cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all prostate: 148.2 Expressed in all +TBC1D2 Armus, PARIS1, TBC1D2A ENSG00000095383 TBC1 domain family member 2 9 98198999-98255721 Predicted intracellular proteins Evidence at protein level HPA030871 Uncertain Approved Nucleus
Cytosol Head and neck cancer:2.77e-4 (unfavourable), Testis cancer:5.62e-4 (unfavourable) Expressed in all Mixed lung: 33.2 Cell line enhanced HaCaT: 86.0 +WHRN CIP98, DFNB31, PDZD7B, USH2D ENSG00000095397 Whirlin 9 114402080-114505450 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA002480, CAB033194 Uncertain Pancreatic cancer:2.28e-4 (favourable) Expressed in all Tissue enhanced adrenal gland: 73.0 testis: 44.4 Cell line enhanced Karpas-707: 96.9;U-266/70: 64.0;U-266/84: 64.8 +PDE6C ACHM5, COD4, PDEA2 ENSG00000095464 Phosphodiesterase 6C 10 93612588-93666010 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Not detected Not detected skin: 0.6 Not detected +CWF19L1 FLJ10998, hDrn1 ENSG00000095485 CWF19-like 1, cell cycle control (S. pombe) 10 100232298-100267680 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036889, HPA036890 Uncertain Approved Nucleoplasm
Golgi apparatus Liver cancer:6.90e-4 (unfavourable) Expressed in all Expressed in all testis: 24.9 Expressed in all +SEMA4G FLJ20590, KIAA1619 ENSG00000095539 Semaphorin 4G 10 100969518-100985871 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA038362, HPA077752 Uncertain Uncertain Vesicles
Lipid droplets Mixed Tissue enhanced rectum: 92.7 duodenum: 53.8 Cell line enhanced A549: 28.9;CACO-2: 25.3;Hep G2: 76.9 +BTAF1 MOT1, TAF-172, TAF(II)170, TAF172, TAFII170 ENSG00000095564 B-TFIID TATA-box binding protein associated factor 1 10 91923769-92030325 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA070682 Approved Nucleoplasm
Vesicles Renal cancer:4.04e-5 (unfavourable), Head and neck cancer:5.07e-4 (favourable) Expressed in all Expressed in all skin: 59.8 Expressed in all +IKZF5 FLJ22973, Pegasus, ZNFN1A5 ENSG00000095574 IKAROS family zinc finger 5 10 122990806-123008817 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015297, HPA051574 Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all bone marrow: 21.3 Expressed in all +BLNK BASH, bca, BLNK-s, Ly57, SLP-65, SLP65 ENSG00000095585 B-cell linker 10 96191702-96271587 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB009333, CAB016291, HPA038309, HPA038310 Enhanced Supported Plasma membrane
Cytoplasmic bodies Urothelial cancer:2.67e-6 (favourable) Expressed in all Mixed spleen: 69.1 Group enriched 5 Daudi: 49.2;REH: 152.1;RPMI-8226: 63.9;U-698: 171.5 +TLL2 ENSG00000095587 Tolloid like 2 10 96364606-96513918 Enzymes, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 1.9 heart muscle: 1.0 Cell line enriched 8 RPTEC TERT1: 15.3 +CYP26A1 CP26, CYP26, P450RAI, P450RAI1 ENSG00000095596 Cytochrome P450 family 26 subfamily A member 1 10 93073475-93077890 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 9 liver: 9.7 cerebral cortex: 1.0 Cell line enriched 8 AF22: 60.5 +TDRD1 CT41.1 ENSG00000095627 Tudor domain containing 1 10 114179270-114232304 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037729 Enhanced Tissue enhanced Tissue enriched 13 testis: 32.0 kidney: 2.3 Cell line enhanced MCF7: 6.3;RH-30: 10.6;SK-BR-3: 38.6;U-266/84: 8.6 +SORBS1 CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12 ENSG00000095637 Sorbin and SH3 domain containing 1 10 95311771-95561414 Predicted intracellular proteins Evidence at protein level HPA027559, HPA043084 Enhanced Supported Plasma membrane
Focal adhesion sites
Centrosome Breast cancer:2.84e-4 (favourable) Expressed in all Expressed in all adipose tissue: 320.1 Cell line enhanced CACO-2: 21.9;HMC-1: 39.4;SK-MEL-30: 30.9 +CRTAC1 ASPIC1, CEP-68, FLJ10320 ENSG00000095713 Cartilage acidic protein 1 10 97865000-98030828 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008175 Enhanced Endometrial cancer:5.01e-6 (unfavourable), Urothelial cancer:1.51e-4 (favourable), Renal cancer:1.85e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 51.0;fallopian tube: 63.6;lung: 76.3;seminal vesicle: 48.1 urinary bladder: 12.8 Cell line enhanced HUVEC TERT2: 6.0;SCLC-21H: 5.6;SK-MEL-30: 6.3;TIME: 8.0 +BAMBI NMA ENSG00000095739 BMP and activin membrane bound inhibitor 10 28677342-28682939 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA010819, HPA010866 Approved Approved Nucleoli fibrillar center
Vesicles
Lipid droplets Liver cancer:9.42e-6 (unfavourable), Renal cancer:5.25e-4 (favourable) Expressed in all Tissue enhanced ovary: 87.8 adrenal gland: 50.0 Cell line enhanced CACO-2: 120.2;SK-MEL-30: 134.8 +IL11 AGIF, IL-11 ENSG00000095752 Interleukin 11 19 55364389-55370463 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044955 Uncertain Mitochondria Pancreatic cancer:7.50e-4 (unfavourable) Mixed Tissue enhanced appendix: 5.7;endometrium: 5.2;gallbladder: 4.9 placenta: 1.7 Cell line enhanced BJ: 50.3;BJ hTERT+: 54.5;hTEC/SVTERT24-B: 54.2;U-251 MG: 179.7 +MYO3A DFNB30 ENSG00000095777 Myosin IIIA 10 25934267-26212527 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048951, HPA051893 Approved Supported Plasma membrane
Actin filaments
Cytoplasmic bodies Mixed Tissue enriched 9 testis: 6.8 skin: 0.8 Cell line enhanced CAPAN-2: 2.0;HEK 293: 2.2;SCLC-21H: 2.3;U-2 OS: 3.7;U-698: 8.6 +WAC BM-016, FLJ31290, MGC10753, PRO1741, Wwp4 ENSG00000095787 WW domain containing adaptor with coiled-coil 10 28532493-28623112 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036528, HPA042609 Approved Supported Nucleoplasm Liver cancer:9.27e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 132.1 Expressed in all +CREM hCREM-2 ENSG00000095794 CAMP responsive element modulator 10 35126791-35212958 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001818, CAB018352 Enhanced Supported Nucleus
Vesicles Renal cancer:1.23e-5 (unfavourable) Expressed in all Expressed in all testis: 339.8 Expressed in all +NUBP2 CFD1 ENSG00000095906 Nucleotide binding protein 2 16 1782901-1789191 Predicted intracellular proteins Evidence at protein level HPA041704 Uncertain Approved Nucleus
Cytosol Renal cancer:9.63e-5 (favourable) Expressed in all Expressed in all spleen: 17.4 Expressed in all +TPSD1 ENSG00000095917 Tryptase delta 1 16 1256059-1258998 Enzymes, Predicted secreted proteins Evidence at protein level CAB002215, CAB032871, HPA040182, HPA049554 Supported Uncertain Nuclear speckles Mixed Tissue enhanced lung: 26.9 gallbladder: 20.3 Group enriched 46 HEL: 25.4;HMC-1: 36.4 +SMIM24 C19orf77, HSPC323 ENSG00000095932 Small integral membrane protein 24 19 3473986-3480542 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045046, HPA056027 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:4.13e-10 (favourable) Tissue enhanced Group enriched 8 duodenum: 758.8;epididymis: 1928.7;kidney: 835.9;small intestine: 682.3 stomach: 140.0 Group enriched 8 CACO-2: 128.5;HEL: 66.3;Hep G2: 79.7;MOLT-4: 90.8;REH: 56.0;U-937: 68.2 +HIVEP1 CIRIP, CRYBP1, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A ENSG00000095951 Human immunodeficiency virus type I enhancer binding protein 1 6 12008762-12164999 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050724 Approved Supported Nucleoplasm
Nuclear bodies
Mitochondria Expressed in all Mixed parathyroid gland: 25.7 Expressed in all +TREM2 TREM-2, Trem2a, Trem2b, Trem2c ENSG00000095970 Triggering receptor expressed on myeloid cells 2 6 41158506-41163186 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010917, HPA012571 Approved Liver cancer:4.24e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 37.0;lung: 40.5 adrenal gland: 16.1 Cell line enhanced HBEC3-KT: 9.0;hTCEpi: 49.6;THP-1: 26.6 +KCNK16 K2p16.1, TALK-1, TALK1 ENSG00000095981 Potassium two pore domain channel subfamily K member 16 6 39314698-39322968 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Tissue enriched Tissue enhanced duodenum: 3.8;pancreas: 5.4;stomach: 12.4 thyroid gland: 1.7 Cell line enriched 511 SCLC-21H: 157.3 +CRISP3 Aeg2, CRISP-3, CRS3, dJ442L6.3, SGP28 ENSG00000096006 Cysteine rich secretory protein 3 6 49727384-49744437 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054392 Supported Group enriched Tissue enhanced fallopian tube: 1885.2;salivary gland: 915.8 esophagus: 288.4 Group enriched 59 HEL: 11.2;RT4: 3.3;SK-BR-3: 6.9;T-47d: 4.2 +FKBP5 FKBP51, FKBP54, P54, PPIase, Ptg-10 ENSG00000096060 FK506 binding protein 5 6 35573585-35728583 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009315, HPA031092, HPA031093, HPA031095 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all adipose tissue: 415.3 Cell line enhanced ASC diff: 517.9;HHSteC: 495.2;HSkMC: 518.9 +SRPK1 SFRSK1 ENSG00000096063 SRSF protein kinase 1 6 35832966-35921342 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016431, HPA056486 Approved Supported Nucleus
Plasma membrane
Cytosol Liver cancer:7.90e-6 (unfavourable), Pancreatic cancer:6.53e-5 (unfavourable) Expressed in all Expressed in all testis: 81.0 Expressed in all +BRPF3 KIAA1286 ENSG00000096070 Bromodomain and PHD finger containing 3 6 36196744-36232790 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022787 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all testis: 38.1 Expressed in all +MRPS18A FLJ10548, MRPS18-3 ENSG00000096080 Mitochondrial ribosomal protein S18A 6 43671303-43687791 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA035450, HPA035451 Approved Thyroid cancer:4.03e-5 (favourable) Expressed in all Expressed in all prostate: 58.1 Expressed in all +PGC ENSG00000096088 Progastricsin 6 41736711-41754109 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031717, HPA031718 Enhanced Supported Nucleus Tissue enhanced Tissue enriched 17 stomach: 22276.5 duodenum: 1302.2 Cell line enriched 11 Hep G2: 171.0 +TMEM14A C6orf73, PTD011 ENSG00000096092 Transmembrane protein 14A 6 52671109-52686588 Predicted membrane proteins Evidence at protein level HPA072536 Approved Approved Nucleoplasm
Endoplasmic reticulum Expressed in all Expressed in all cerebral cortex: 88.1 Expressed in all +EFHC1 EJM, EJM1, FLJ10466 ENSG00000096093 EF-hand domain containing 1 6 52362123-52529886 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035307 Approved Uncertain Plasma membrane
Cytosol Pancreatic cancer:2.33e-4 (favourable), Renal cancer:3.29e-4 (unfavourable) Expressed in all Tissue enhanced fallopian tube: 55.6 testis: 31.3 Cell line enhanced SCLC-21H: 22.6 +NCR2 CD336, LY95, NK-p44 ENSG00000096264 Natural cytotoxicity triggering receptor 2 6 41335655-41350887 CD markers, Predicted membrane proteins Evidence at protein level HPA067249 Uncertain Not detected Not detected duodenum: 0.5 Not detected +HSP90AB1 HSPC2, HSPCB ENSG00000096384 Heat shock protein 90 alpha family class B member 1 6 44246166-44253888 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005230, HPA055729, HPA072606, HPA074351 Enhanced Supported Cytosol Ovarian cancer:4.03e-4 (favourable), Renal cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all ovary: 1461.8 Expressed in all +MLN ENSG00000096395 Motilin 6 33794673-33804011 Predicted secreted proteins Evidence at protein level HPA069392 Enhanced Tissue enriched Tissue enriched 6 duodenum: 253.3 small intestine: 42.3 Cell line enhanced CACO-2: 2.4;TIME: 1.1 +CDC5L CDC5, CEF1, hCDC5, PCDC5RP ENSG00000096401 Cell division cycle 5 like 6 44387525-44450426 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006302, HPA011361, CAB012275 Supported Supported Nucleoplasm Melanoma:7.02e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.0 Expressed in all +ITPR3 IP3R3 ENSG00000096433 Inositol 1,4,5-trisphosphate receptor type 3 6 33620365-33696574 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA003915, HPA064704 Approved Uncertain Vesicles Expressed in all Mixed skin: 65.1 Mixed +ZNF184 ENSG00000096654 Zinc finger protein 184 6 27450743-27473118 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003226, HPA064793 Uncertain Supported Nucleus Ovarian cancer:4.41e-5 (favourable) Expressed in all Mixed testis: 15.2 Expressed in all +DSP DPI, DPII, KPPS2, PPKS2 ENSG00000096696 Desmoplakin 6 7541575-7586717 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037324, HPA045840, HPA054950 Enhanced Enhanced Cell Junctions Renal cancer:1.53e-9 (favourable), Urothelial cancer:1.82e-4 (unfavourable) Tissue enhanced Group enriched 8 esophagus: 345.7;skin: 1016.4 placenta: 89.1 Cell line enhanced BEWO: 263.2;HaCaT: 265.1;hTCEpi: 482.9 +SIRT1 SIR2L1 ENSG00000096717 Sirtuin 1 10 67884669-67918390 Predicted intracellular proteins Evidence at protein level CAB003855, HPA006295, HPA052351 Approved Enhanced Nucleus
Mitochondria
Cytosol Expressed in all Expressed in all testis: 49.0 Expressed in all +HNRNPH3 2H9, HNRPH3 ENSG00000096746 Heterogeneous nuclear ribonucleoprotein H3 10 68331174-68343191 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038264 Supported Nucleoplasm Liver cancer:2.30e-5 (unfavourable) Expressed in all Expressed in all endometrium: 154.2 Expressed in all +IFT74 CCDC2, CMG-1, CMG1, FLJ22621 ENSG00000096872 Intraflagellar transport 74 9 26947039-27062930 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020247, HPA026684 Approved Approved Golgi apparatus Expressed in all Expressed in all testis: 84.2 Mixed +JAK2 JTK10 ENSG00000096968 Janus kinase 2 9 4984390-5128183 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013089, HPA040820, HPA043870 Approved Supported Nucleoplasm
Plasma membrane
Focal adhesion sites Expressed in all Mixed appendix: 28.1 Group enriched 6 ASC diff: 34.8;HDLM-2: 71.3;HEL: 140.3 +IL12RB1 CD212, IL12RB ENSG00000096996 Interleukin 12 receptor subunit beta 1 19 18058995-18098944 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA074414 Approved Plasma membrane Renal cancer:5.90e-5 (unfavourable), Cervical cancer:3.41e-4 (favourable) Mixed Tissue enhanced lymph node: 25.9 spleen: 20.6 Cell line enhanced Daudi: 13.1;HDLM-2: 28.9;Karpas-707: 36.8 +ABL1 ABL, c-ABL, JTK7, p150 ENSG00000097007 ABL proto-oncogene 1, non-receptor tyrosine kinase 9 130713946-130887675 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002686, HPA027251, HPA027280, HPA028409 Supported Enhanced Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 83.9 Expressed in all +ACOT7 ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126 ENSG00000097021 Acyl-CoA thioesterase 7 1 6264269-6394391 Enzymes, Predicted intracellular proteins Evidence at protein level HPA025735, HPA025762 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:2.55e-6 (unfavourable), Liver cancer:2.31e-5 (unfavourable), Lung cancer:1.29e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 129.2 small intestine: 62.3 Expressed in all +SH3GLB1 Bif-1, CGI-61, KIAA0491, PPP1R70 ENSG00000097033 SH3 domain containing GRB2 like endophilin B1 1 86704570-86748184 Predicted intracellular proteins Evidence at protein level CAB004650, HPA015608, HPA019900 Enhanced Enhanced Cytosol Liver cancer:2.90e-5 (unfavourable), Pancreatic cancer:2.53e-4 (unfavourable) Expressed in all Expressed in all testis: 198.5 Expressed in all +CDC7 CDC7L1, HsCdc7, Hsk1, huCdc7 ENSG00000097046 Cell division cycle 7 1 91500893-91525764 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002669, HPA035831 Enhanced Supported Nucleoplasm
Cytokinetic bridge
Mitotic spindle Renal cancer:1.89e-15 (unfavourable), Liver cancer:3.15e-6 (unfavourable) Expressed in all Tissue enhanced testis: 32.0 spleen: 17.2 Expressed in all +SYDE2 FLJ13815 ENSG00000097096 Synapse defective Rho GTPase homolog 2 1 85156873-85201046 Predicted intracellular proteins Evidence at protein level HPA027138, HPA058378 Uncertain Approved Nucleoli
Golgi apparatus Mixed Mixed parathyroid gland: 7.0 Cell line enhanced BEWO: 13.9 +PCSK5 PC5, PC6, SPC6 ENSG00000099139 Proprotein convertase subtilisin/kexin type 5 9 75890644-76362339 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA031072 Enhanced Supported Golgi apparatus Renal cancer:9.61e-5 (unfavourable) Mixed Mixed small intestine: 28.1 Cell line enhanced BEWO: 31.5;HaCaT: 41.2;RPTEC TERT1: 32.1;U-2 OS: 68.5 +SCD FADS5, SCDOS ENSG00000099194 Stearoyl-CoA desaturase 10 100347124-100364834 Enzymes, Predicted membrane proteins Evidence at protein level HPA012107, HPA063921 Uncertain Enhanced Endoplasmic reticulum Renal cancer:7.56e-5 (unfavourable), Urothelial cancer:7.79e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 1255.0 Expressed in all +TMED1 Il1rl1l, IL1RL1LG, MGC1270, p24g1, p24gamma1, ST2L ENSG00000099203 Transmembrane p24 trafficking protein 1 19 10832438-10836318 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA018507 Uncertain Renal cancer:8.66e-5 (favourable) Expressed in all Expressed in all thyroid gland: 47.6 Expressed in all +ABLIM1 ABLIM, LIMAB1, limatin ENSG00000099204 Actin binding LIM protein 1 10 114431113-114685003 Predicted intracellular proteins Evidence at protein level HPA038951, HPA038952 Approved Supported Cytosol Renal cancer:2.72e-5 (favourable) Expressed in all Expressed in all ovary: 284.7 Mixed +ERMP1 FLJ23309, FXNA, KIAA1815 ENSG00000099219 Endoplasmic reticulum metallopeptidase 1 9 5765076-5833117 Enzymes, Predicted membrane proteins Evidence at protein level HPA020584 Uncertain Approved Nucleus
Nucleoli Renal cancer:5.83e-10 (favourable) Expressed in all Tissue enhanced parathyroid gland: 124.7 thyroid gland: 44.0 Cell line enhanced RT4: 122.7 +RAB18 ENSG00000099246 RAB18, member RAS oncogene family 10 27504174-27542237 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA025928 Uncertain Expressed in all Expressed in all cerebral cortex: 87.9 Expressed in all +NRP1 CD304, NRP, VEGF165R ENSG00000099250 Neuropilin 1 10 33177492-33336262 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004511, HPA030278 Approved Uncertain Mitochondria Stomach cancer:1.22e-5 (unfavourable), Cervical cancer:7.10e-5 (unfavourable), Renal cancer:3.87e-4 (unfavourable), Glioma:7.78e-4 (unfavourable) Expressed in all Expressed in all placenta: 194.1 Cell line enhanced U-87 MG: 437.4 +PRTFDC1 HHGP ENSG00000099256 Phosphoribosyl transferase domain containing 1 10 24848607-24952604 Predicted intracellular proteins Evidence at protein level HPA021458 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:9.27e-5 (unfavourable), Endometrial cancer:2.66e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 47.5 Cell line enhanced CACO-2: 62.8;CAPAN-2: 82.9 +PALMD C1orf11, FLJ20271, PALML ENSG00000099260 Palmdelphin 1 99645943-99694541 Predicted intracellular proteins Evidence at protein level HPA017959, HPA030549 Supported Supported Plasma membrane
Actin filaments
Focal adhesion sites Head and neck cancer:5.90e-5 (favourable), Endometrial cancer:9.42e-4 (favourable) Expressed in all Tissue enhanced adipose tissue: 141.1 placenta: 60.5 Cell line enhanced HUVEC TERT2: 126.3;TIME: 174.6;U-87 MG: 88.7 +TSPAN15 NET-7, TM4SF15 ENSG00000099282 Tetraspanin 15 10 69451473-69507669 Predicted membrane proteins, Transporters Evidence at protein level HPA044657 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.25e-4 (unfavourable), Liver cancer:8.00e-4 (unfavourable) Expressed in all Mixed stomach: 72.3 Cell line enhanced CAPAN-2: 136.3;EFO-21: 199.5;MCF7: 128.3;PC-3: 248.2 +H2AFY2 macroH2A2 ENSG00000099284 H2A histone family member Y2 10 70052796-70112280 Predicted intracellular proteins Evidence at protein level HPA035865, HPA041189 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all endometrium: 31.3 Cell line enhanced AF22: 166.7;SCLC-21H: 146.5;SH-SY5Y: 128.2 +WASHC2A bA56A21.1, bA98I6.1, FAM21A, FAM21B, FLJ10824 ENSG00000099290 WASH complex subunit 2A 10 50067888-50133506 Predicted intracellular proteins Evidence at protein level HPA047844, HPA060975, HPA061022 Supported Supported Nucleoli
Vesicles
Cytosol Liver cancer:6.75e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.7 Expressed in all +MAST3 KIAA0561 ENSG00000099308 Microtubule associated serine/threonine kinase 3 19 18097793-18151692 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035061, HPA035062 Uncertain Approved Nuclear speckles Head and neck cancer:2.97e-4 (favourable), Pancreatic cancer:7.01e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 51.5 Mixed +MZF1 MZF-1, MZF1B, Zfp98, ZNF42, ZSCAN6 ENSG00000099326 Myeloid zinc finger 1 19 58561931-58573575 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001757 Approved Supported Nucleus Renal cancer:2.83e-8 (unfavourable), Urothelial cancer:4.09e-5 (favourable), Pancreatic cancer:7.97e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 14.6 Cell line enhanced HEK 293: 39.4 +OCEL1 FLJ22709 ENSG00000099330 Occludin/ELL domain containing 1 19 17226204-17229219 Predicted intracellular proteins Evidence at protein level HPA042070, HPA043223 Uncertain Approved Golgi apparatus Expressed in all Expressed in all epididymis: 22.2 Expressed in all +MYO9B CELIAC4 ENSG00000099331 Myosin IXB 19 17075781-17214537 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB037190, HPA042043 Approved Supported Cytosol Renal cancer:5.66e-6 (unfavourable), Ovarian cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all spleen: 98.8 Expressed in all +KCNK6 K2p6.1, TWIK-2 ENSG00000099337 Potassium two pore domain channel subfamily K member 6 19 38319844-38332076 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB022637, HPA040184 Uncertain Approved Plasma membrane
Actin filaments
Cytosol Endometrial cancer:1.45e-6 (favourable), Renal cancer:1.04e-5 (unfavourable) Expressed in all Mixed endometrium: 22.6 Cell line enhanced HEL: 33.9;HMC-1: 35.7 +CATSPERG C19orf15, DKFZp434A1022, FLJ46353 ENSG00000099338 Cation channel sperm associated auxiliary subunit gamma 19 38335775-38370943 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA052777 Approved Nucleus
Nucleoli
Cytosol Mixed Tissue enriched 41 testis: 48.6 skin: 1.1 Cell line enhanced BEWO: 1.4;HMC-1: 1.6;MCF7: 1.2 +PSMD8 HIP6, HYPF, Nin1p, p31, Rpn12, S14 ENSG00000099341 Proteasome 26S subunit, non-ATPase 8 19 38374536-38383824 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006702, CAB021101 Enhanced Approved Nuclear speckles
Cytosol Endometrial cancer:3.84e-4 (unfavourable), Renal cancer:4.66e-4 (unfavourable) Expressed in all Expressed in all testis: 195.0 Expressed in all +FBXL19 CXXC11, DKFZp434K0410, Fbl19, JHDM1C ENSG00000099364 F-box and leucine rich repeat protein 19 16 30923055-30948783 Predicted intracellular proteins Evidence at protein level HPA035317 Approved Intermediate filaments Cervical cancer:3.27e-4 (unfavourable), Liver cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all testis: 35.5 Expressed in all +STX1B STX1B1, STX1B2 ENSG00000099365 Syntaxin 1B 16 30989256-31010661 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA069176, CAB079008 Supported Supported Tissue enriched Tissue enriched 22 cerebral cortex: 108.6 testis: 4.8 Cell line enhanced hTEC/SVTERT24-B: 11.1 +HSD3B7 C(27)-3BETA-HSD, SDR11E3 ENSG00000099377 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 16 30985207-30989152 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050521, HPA060847 Uncertain Supported Lipid droplets Renal cancer:1.60e-6 (unfavourable), Colorectal cancer:5.95e-4 (unfavourable) Expressed in all Expressed in all liver: 21.9 Cell line enhanced HDLM-2: 83.9;HMC-1: 85.9;U-2197: 89.0 +SETD1A KIAA0339, KMT2F, Set1 ENSG00000099381 SET domain containing 1A 16 30957294-30984664 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020646, HPA058376 Enhanced Supported Nuclear speckles Liver cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all testis: 24.5 Expressed in all +BCL7C ENSG00000099385 BCL tumor suppressor 7C 16 30833626-30894960 Predicted intracellular proteins Evidence at protein level HPA018676, HPA052654 Uncertain Approved Nucleoplasm Cervical cancer:4.23e-4 (favourable) Expressed in all Expressed in all ovary: 29.7 Expressed in all +MAGEB2 CT3.2, DAM6, MAGE-XP-2, MGC26438 ENSG00000099399 MAGE family member B2 X 30215560-30220089 Predicted intracellular proteins Evidence at protein level HPA065224, HPA074544, HPA075519 Enhanced Approved Nucleoplasm
Vesicles
Cytosol Tissue enriched Tissue enriched 74 testis: 54.2 placenta: 0.7 Group enriched 9 HL-60: 72.9;K-562: 59.4;Karpas-707: 55.2;U-2 OS: 93.7;U-266/70: 113.8;U-266/84: 116.9 +EFNA2 ELF-1, EPLG6, LERK6 ENSG00000099617 Ephrin A2 19 1286154-1300237 Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB005178, HPA067567 Uncertain Approved Mitochondria
Cytosol Tissue enhanced Group enriched 6 colon: 7.0;duodenum: 7.9;small intestine: 10.6 rectum: 1.5 Cell line enhanced Hep G2: 6.6;NTERA-2: 5.4;REH: 6.8;SH-SY5Y: 17.8;U-2 OS: 5.8 +CIRBP CIRP ENSG00000099622 Cold inducible RNA binding protein 19 1259384-1274880 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060537 Supported Nucleus
Nucleoli Renal cancer:3.65e-7 (favourable), Endometrial cancer:1.36e-4 (favourable), Lung cancer:2.50e-4 (favourable), Pancreatic cancer:2.69e-4 (favourable), Cervical cancer:3.63e-4 (favourable) Expressed in all Expressed in all ovary: 1042.3 Expressed in all +ATP5D ENSG00000099624 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 19 1241746-1244826 Predicted intracellular proteins Evidence at protein level HPA002865 Uncertain Renal cancer:3.46e-5 (favourable), Endometrial cancer:1.23e-4 (favourable), Pancreatic cancer:4.60e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 217.6 Expressed in all +CBARP BARP, C19orf26, DOS, MGC40084 ENSG00000099625 CACN beta subunit associated regulatory protein 19 1228287-1238027 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012777 Approved Nucleoplasm Tissue enhanced Tissue enhanced adrenal gland: 2.4;cerebral cortex: 7.0 skin: 1.1 Cell line enhanced SH-SY5Y: 5.6 +PCDH11Y PCDH22, PCDHY ENSG00000099715 Protocadherin 11 Y-linked Y 5000226-5742224 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000432 Uncertain Not detected Tissue enriched 6 cerebral cortex: 4.4 placenta,seminal vesicle: 0.7 Not detected +AMELY AMGL ENSG00000099721 Amelogenin, Y-linked Y 6865918-6874027 Predicted secreted proteins Evidence at transcript level Not detected Not detected thyroid gland: 0.2 Not detected +IGFALS ALS ENSG00000099769 Insulin like growth factor binding protein acid labile subunit 16 1790413-1794971 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA040692, HPA040948 Approved Supported Nucleoplasm Liver cancer:5.97e-4 (favourable), Endometrial cancer:6.06e-4 (unfavourable) Tissue enhanced Group enriched 6 liver: 25.0;stomach: 6.6 gallbladder: 2.5 Cell line enhanced Hep G2: 1.2;U-266/70: 1.3 +HNRNPM CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1 ENSG00000099783 Heterogeneous nuclear ribonucleoprotein M 19 8444767-8489114 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016113, HPA024344 Supported Enhanced Nucleoplasm Liver cancer:1.80e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 203.0 Expressed in all +MARCH2 HSPC240, MARCH-II, RNF172 ENSG00000099785 Membrane associated ring-CH-type finger 2 19 8413270-8439017 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014063 Approved Approved Cytosol Endometrial cancer:1.05e-5 (favourable), Pancreatic cancer:6.21e-4 (favourable), Colorectal cancer:6.48e-4 (unfavourable), Head and neck cancer:8.29e-4 (favourable) Expressed in all Expressed in all epididymis: 64.8 Mixed +NDUFB7 B18, CI-B18, MGC2480 ENSG00000099795 NADH:ubiquinone oxidoreductase subunit B7 19 14566078-14572062 Predicted intracellular proteins Evidence at protein level HPA002817 Approved Renal cancer:2.41e-4 (favourable), Cervical cancer:3.54e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 248.7 Expressed in all +TECR GPSN2, MRT14, SC2, TER ENSG00000099797 Trans-2,3-enoyl-CoA reductase 19 14517085-14565980 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029780, HPA056488 Supported Supported Endoplasmic reticulum Urothelial cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 404.6 Expressed in all +TIMM13 Tim13, TIMM13B ENSG00000099800 Translocase of inner mitochondrial membrane 13 19 2425624-2427894 Predicted intracellular proteins Evidence at protein level HPA048985 Uncertain Supported Nucleoli fibrillar center
Mitochondria Renal cancer:3.88e-5 (favourable), Endometrial cancer:4.68e-5 (favourable), Pancreatic cancer:9.77e-4 (favourable) Expressed in all Expressed in all adrenal gland: 53.1 Expressed in all +CDC34 E2-CDC34, UBC3, UBE2R1 ENSG00000099804 Cell division cycle 34 19 531712-542092 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA002382, CAB005109, CAB047311 Approved Supported Nuclear speckles
Cytosol Liver cancer:7.57e-4 (unfavourable) Expressed in all Expressed in all testis: 63.5 Expressed in all +MTAP c86fus, MSAP ENSG00000099810 Methylthioadenosine phosphorylase 9 21802543-21937651 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046915 Supported Cytosol Liver cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 15.7 Mixed +MISP C19orf21, Caprice, DKFZp686H18209, MISP1 ENSG00000099812 Mitotic spindle positioning 19 751126-764318 Predicted intracellular proteins Evidence at protein level HPA049511, HPA062232 Enhanced Enhanced Plasma membrane
Focal adhesion sites Tissue enhanced Group enriched 6 colon: 94.7;duodenum: 173.3;rectum: 52.6;small intestine: 217.1 stomach: 21.6 Cell line enhanced A549: 110.0;HaCaT: 79.4;hTCEpi: 59.7;SK-BR-3: 101.1 +CEP170B Cep170R, FAM68C, KIAA0284 ENSG00000099814 Centrosomal protein 170B 14 104865280-104896770 Predicted intracellular proteins Evidence at protein level HPA000871, HPA059017 Enhanced Approved Centrosome
Cytosol Renal cancer:3.26e-4 (favourable), Prostate cancer:4.41e-4 (unfavourable), Liver cancer:6.12e-4 (unfavourable) Expressed in all Mixed skin: 30.5 Mixed +POLR2E hRPB25, hsRPB5, RPABC1, RPB5, XAP4 ENSG00000099817 RNA polymerase II subunit E 19 1086579-1095380 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA063030, HPA068992 Supported Supported Nucleoplasm Renal cancer:3.21e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 42.5 Expressed in all +POLRMT APOLMT, h-mtRPOL, MTRNAP, MTRPOL ENSG00000099821 RNA polymerase mitochondrial 19 617224-633604 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006366 Uncertain Supported Mitochondria Endometrial cancer:4.50e-4 (favourable) Expressed in all Expressed in all testis: 46.8 Expressed in all +HCN2 BCNG-2, BCNG2, HAC-1 ENSG00000099822 Hyperpolarization activated cyclic nucleotide gated potassium channel 2 19 589893-617159 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Renal cancer:6.99e-5 (unfavourable) Group enriched Tissue enriched 5 cerebral cortex: 38.3 heart muscle: 7.0 Cell line enhanced A549: 27.1;MCF7: 21.7;U-138 MG: 20.0;U-87 MG: 40.9 +CDHR5 FLJ20219, MU-PCDH, MUCDHL, MUPCDH ENSG00000099834 Cadherin related family member 5 11 616565-626078 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA009081, HPA009173, CAB025004 Enhanced Group enriched Group enriched 9 colon: 41.7;duodenum: 82.7;kidney: 23.6;liver: 21.0;rectum: 54.3;small intestine: 64.3 gallbladder: 5.3 Cell line enhanced CACO-2: 2.1 +IZUMO4 C19orf36 ENSG00000099840 IZUMO family member 4 19 2096429-2099593 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA045099, HPA048496 Enhanced Uncertain Nucleoplasm
Vesicles Pancreatic cancer:1.69e-4 (favourable), Endometrial cancer:7.08e-4 (favourable) Mixed Tissue enriched 52 testis: 341.9 ovary: 6.5 Cell line enhanced Karpas-707: 6.0;RPMI-8226: 7.2 +RASSF7 C11orf13, HRAS1, HRC1 ENSG00000099849 Ras association domain family member 7 11 560404-564021 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA078015 Supported Microtubule organizing center Glioma:8.86e-4 (unfavourable) Expressed in all Mixed fallopian tube: 44.4 Cell line enhanced CAPAN-2: 75.6;HaCaT: 76.6 +GADD45B DKFZP566B133, GADD45BETA, MYD118 ENSG00000099860 Growth arrest and DNA damage inducible beta 19 2476122-2478259 Predicted intracellular proteins Evidence at protein level HPA029816 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all bone marrow: 218.1 Mixed +PALM KIAA0270 ENSG00000099864 Paralemmin 19 708939-748329 Predicted intracellular proteins Evidence at protein level HPA041713, HPA049578 Approved Enhanced Nucleus
Plasma membrane Renal cancer:5.44e-4 (favourable), Pancreatic cancer:9.81e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 84.8 adipose tissue: 53.1 Cell line enhanced AN3-CA: 28.0;EFO-21: 25.9;REH: 46.8;SH-SY5Y: 33.4 +MADCAM1 MACAM1 ENSG00000099866 Mucosal vascular addressin cell adhesion molecule 1 19 489176-505342 Predicted membrane proteins Evidence at protein level CAB075699 Enhanced Mixed Tissue enhanced appendix: 17.8;spleen: 11.4 gallbladder: 3.3 Mixed +MKNK2 GPRK7, MNK2 ENSG00000099875 MAP kinase interacting serine/threonine kinase 2 19 2037465-2051244 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021875, CAB037253, HPA070499 Enhanced Supported Nuclear bodies Endometrial cancer:4.86e-5 (favourable), Stomach cancer:4.01e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 174.3 Expressed in all +ARVCF ENSG00000099889 Armadillo repeat gene deleted in velocardiofacial syndrome 22 19969896-20016808 Predicted intracellular proteins Evidence at protein level CAB016162, HPA055264, HPA063675 Enhanced Enhanced Plasma membrane
Cell Junctions Urothelial cancer:5.76e-6 (favourable) Expressed in all Mixed spleen: 8.8 Cell line enhanced K-562: 18.0;SCLC-21H: 21.2;SH-SY5Y: 14.7;U-2 OS: 16.4 +TRMT2A HTF9C ENSG00000099899 TRNA methyltransferase 2 homolog A 22 20111866-20117392 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001077 Approved Approved Nucleus
Cytosol Renal cancer:2.99e-8 (unfavourable) Expressed in all Expressed in all spleen: 16.6 Expressed in all +RANBP1 HTF9A ENSG00000099901 RAN binding protein 1 22 20115938-20127357 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065868, HPA065931 Enhanced Supported Cytosol Renal cancer:1.16e-6 (unfavourable), Liver cancer:1.58e-6 (unfavourable) Expressed in all Expressed in all testis: 152.5 Expressed in all +ZDHHC8 KIAA1292, ZNF378 ENSG00000099904 Zinc finger DHHC-type containing 8 22 20129456-20148007 Enzymes, Predicted membrane proteins Evidence at protein level HPA003422 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:4.04e-4 (unfavourable), Cervical cancer:9.68e-4 (unfavourable) Expressed in all Expressed in all spleen: 29.7 Mixed +KLHL22 FLJ14360, KELCHL ENSG00000099910 Kelch like family member 22 22 20441519-20495883 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040766 Supported Golgi apparatus
Cytokinetic bridge
Mitotic spindle Renal cancer:1.34e-8 (favourable), Pancreatic cancer:3.85e-6 (favourable), Endometrial cancer:4.88e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 35.6 Mixed +MED15 Arc105, CAG7A, PCQAP, TIG-1, TNRC7 ENSG00000099917 Mediator complex subunit 15 22 20495913-20587632 Predicted intracellular proteins Evidence at protein level HPA003179 Approved Supported Nucleus Endometrial cancer:7.30e-5 (favourable), Renal cancer:1.61e-4 (unfavourable), Liver cancer:3.71e-4 (unfavourable), Pancreatic cancer:9.09e-4 (unfavourable) Expressed in all Expressed in all spleen: 43.5 Expressed in all +SERPIND1 D22S673, HC-II, HC2, HCF2, HLS2 ENSG00000099937 Serpin family D member 1 22 20773879-20787720 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB008639, HPA055767 Supported Approved Vesicles Endometrial cancer:4.09e-4 (favourable) Tissue enriched Tissue enriched 16 liver: 585.3 parathyroid gland: 36.2 Cell line enriched 8 Hep G2: 126.1 +SNAP29 CEDNIK, SNAP-29 ENSG00000099940 Synaptosome associated protein 29 22 20858983-20891218 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031823, CAB037092, HPA056492 Supported Supported Nucleoplasm
Cytosol Cervical cancer:6.99e-4 (favourable) Expressed in all Expressed in all testis: 74.6 Expressed in all +CRKL ENSG00000099942 CRK like proto-oncogene, adaptor protein 22 20917426-20953749 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000532, HPA001100 Uncertain Enhanced Nucleoplasm
Cytosol Renal cancer:8.82e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 53.4 Expressed in all +LZTR1 BTBD29, LZTR-1 ENSG00000099949 Leucine zipper like transcription regulator 1 22 20979462-20999038 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA068772, HPA071248 Approved Liver cancer:5.15e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.9 Expressed in all +MMP11 STMY3 ENSG00000099953 Matrix metallopeptidase 11 22 23768226-23784316 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level CAB002593, HPA068864 Approved Renal cancer:2.62e-4 (unfavourable) Expressed in all Group enriched 9 cervix, uterine: 31.6;endometrium: 123.1;placenta: 28.0 smooth muscle: 6.9 Cell line enhanced AN3-CA: 17.4;REH: 7.4 +CECR2 KIAA1740 ENSG00000099954 CECR2, histone acetyl-lysine reader 22 17359949-17558149 Predicted intracellular proteins Evidence at protein level HPA002943 Approved Approved Nucleus
Vesicles Tissue enriched Tissue enhanced cerebral cortex: 7.8 skeletal muscle: 7.5 Cell line enhanced AF22: 15.3;HAP1: 14.9;NTERA-2: 22.8;SCLC-21H: 11.9 +SMARCB1 BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5L1, Snr1 ENSG00000099956 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 22 23786963-23834516 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009196, HPA018248, HPA019127 Supported Supported Nucleoplasm
Nucleoli fibrillar center Renal cancer:1.14e-6 (favourable), Liver cancer:6.52e-4 (unfavourable) Expressed in all Expressed in all testis: 51.2 Expressed in all +P2RX6 MGC129625, P2RXL1, P2X6, P2XM ENSG00000099957 Purinergic receptor P2X 6 22 21009808-21028830 Predicted membrane proteins Evidence at protein level HPA028776, HPA028777 Approved Approved Nucleoli
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 3.4;skeletal muscle: 3.0 spleen: 2.3 Cell line enhanced LHCN-M2: 5.6;RH-30: 4.0;U-87 MG: 11.5 +DERL3 C22orf14, derlin-3, FLJ43842, IZP6, MGC71803 ENSG00000099958 Derlin 3 22 23834503-23839128 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB037234, HPA049306 Uncertain Uncertain Vesicles Renal cancer:7.76e-13 (unfavourable), Cervical cancer:8.70e-5 (favourable), Head and neck cancer:8.01e-4 (favourable) Expressed in all Mixed stomach: 39.0 Group enriched 5 Karpas-707: 58.5;RPMI-8226: 33.7;U-266/70: 66.4;U-698: 14.5 +SLC7A4 CAT-4, HCAT3, VH ENSG00000099960 Solute carrier family 7 member 4 22 21028718-21032840 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA031023 Enhanced Mixed Tissue enhanced testis: 22.5 esophagus: 6.0 Cell line enriched 24 BEWO: 135.5 +BCL2L13 BCL-RAMBO, MIL1 ENSG00000099968 BCL2 like 13 22 17628855-17730855 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002052, HPA030994, HPA050377 Uncertain Supported Mitochondria Renal cancer:1.96e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 46.7 Expressed in all +DDTL ENSG00000099974 D-dopachrome tautomerase-like 22 23966901-23972532 Predicted intracellular proteins Evidence at transcript level Liver cancer:5.98e-4 (favourable) Expressed in all Mixed small intestine: 3.5 Mixed +DDT DDCT ENSG00000099977 D-dopachrome tautomerase 22 23971365-23980469 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049871 Approved Approved Mitochondria Expressed in all Expressed in all liver: 109.9 Expressed in all +OSM MGC20461 ENSG00000099985 Oncostatin M 22 30262829-30266840 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.03e-5 (unfavourable) Mixed Tissue enhanced bone marrow: 78.7 appendix: 20.1 Cell line enhanced HDLM-2: 14.6;HMC-1: 9.7;NB-4: 4.2 +CABIN1 KIAA0330, PPP3IN ENSG00000099991 Calcineurin binding protein 1 22 24011192-24178628 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043296 Approved Approved Nucleoplasm
Aggresome
Cytosol Endometrial cancer:9.57e-5 (favourable), Renal cancer:2.94e-4 (favourable) Expressed in all Expressed in all thyroid gland: 33.9 Expressed in all +TBC1D10A AC004997.C22.2, EPI64, TBC1D10 ENSG00000099992 TBC1 domain family member 10A 22 30291990-30327046 Predicted intracellular proteins Evidence at protein level HPA007725, HPA008142, HPA076041 Approved Enhanced Plasma membrane Expressed in all Mixed esophagus: 31.2 Expressed in all +SUSD2 BK65A6.2, FLJ22778 ENSG00000099994 Sushi domain containing 2 22 24181259-24189110 Predicted membrane proteins Evidence at protein level HPA004117 Enhanced Approved Plasma membrane Renal cancer:3.29e-5 (unfavourable) Expressed in all Tissue enhanced lung: 139.3 small intestine: 35.2 Cell line enriched 33 SK-BR-3: 622.4 +SF3A1 Prp21, PRPF21, SAP114, SF3a120 ENSG00000099995 Splicing factor 3a subunit 1 22 30331988-30356947 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000690, HPA030083 Enhanced Enhanced Nuclear speckles Renal cancer:1.16e-4 (favourable) Expressed in all Expressed in all testis: 88.7 Expressed in all +GGT5 GGT-REL, GGTLA1 ENSG00000099998 Gamma-glutamyltransferase 5 22 24219654-24245142 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008121, CAB032489 Uncertain Approved Nucleoli fibrillar center Renal cancer:6.36e-5 (unfavourable), Stomach cancer:4.06e-4 (unfavourable), Testis cancer:6.97e-4 (unfavourable) Expressed in all Mixed adipose tissue: 67.3 Cell line enhanced ASC diff: 113.5;ASC TERT1: 87.8;HHSteC: 197.7;HSkMC: 197.7;TIME: 90.0 +RNF215 ENSG00000099999 Ring finger protein 215 22 30368811-30421771 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA029427, HPA056498 Approved Approved Nucleoli
Microtubules Renal cancer:6.37e-10 (unfavourable) Expressed in all Expressed in all cerebral cortex: 19.2 Expressed in all +SEC14L2 C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1 ENSG00000100003 SEC14 like lipid binding 2 22 30396857-30425317 Predicted intracellular proteins Evidence at protein level HPA064466 Approved Supported Nucleus
Cytosol Head and neck cancer:7.63e-6 (unfavourable), Breast cancer:3.05e-4 (favourable) Expressed in all Tissue enhanced epididymis: 104.9;liver: 125.6;prostate: 83.0 breast: 57.3 Cell line enhanced HBEC3-KT: 61.6 +SEC14L3 TAP2 ENSG00000100012 SEC14 like lipid binding 3 22 30447959-30472049 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059450 Uncertain Not detected Tissue enhanced bone marrow: 2.3;lung: 1.5;thyroid gland: 2.8 liver: 1.4 Not detected +SPECC1L CYTSA, KIAA0376 ENSG00000100014 Sperm antigen with calponin homology and coiled-coil domains 1 like 22 24270817-24417740 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA070614 Uncertain Supported Actin filaments Pancreatic cancer:7.92e-4 (favourable) Expressed in all Expressed in all testis: 58.2 Expressed in all +PPIL2 CYC4, Cyp-60, UBOX7 ENSG00000100023 Peptidylprolyl isomerase like 2 22 21666009-21700015 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035344, HPA055637 Supported Enhanced Nucleoplasm Expressed in all Expressed in all thyroid gland: 31.5 Expressed in all +UPB1 BUP1 ENSG00000100024 Beta-ureidopropionase 1 22 24494107-24528390 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000728 Enhanced Liver cancer:2.30e-7 (favourable) Tissue enriched Group enriched 23 kidney: 51.2;liver: 161.7 testis: 4.6 Cell line enhanced CACO-2: 6.0;NB-4: 1.9;THP-1: 2.7;U-937: 3.5 +YPEL1 ENSG00000100027 Yippee like 1 22 21697544-21735834 Predicted intracellular proteins Evidence at transcript level HPA030501, HPA045621 Uncertain Endometrial cancer:3.09e-5 (unfavourable) Mixed Tissue enhanced testis: 36.6 cerebral cortex: 16.2 Cell line enhanced AF22: 9.6;MOLT-4: 10.8;REH: 10.9;SCLC-21H: 13.5 +SNRPD3 Sm-D3, SMD3 ENSG00000100028 Small nuclear ribonucleoprotein D3 polypeptide 22 24555503-24609980 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001170 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all thyroid gland: 78.0 Expressed in all +PES1 PES ENSG00000100029 Pescadillo ribosomal biogenesis factor 1 22 30576625-30607083 Predicted intracellular proteins Evidence at protein level HPA040210, HPA062439, HPA066670 Supported Enhanced Nucleus
Nucleoli Liver cancer:1.84e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.0 Expressed in all +MAPK1 ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2 ENSG00000100030 Mitogen-activated protein kinase 1 22 21754500-21867680 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA003995, CAB004229, HPA005700, HPA030069 Approved Liver cancer:4.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 132.4 Expressed in all +GGT1 CD224, D22S672, D22S732, GGT ENSG00000100031 Gamma-glutamyltransferase 1 22 24583750-24629005 Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA045635, HPA047534, HPA065444 Supported Approved Vesicles Renal cancer:4.83e-4 (favourable), Ovarian cancer:7.44e-4 (favourable) Expressed in all Tissue enhanced kidney: 161.2 small intestine: 95.9 Cell line enhanced HDLM-2: 148.2;Karpas-707: 162.6;RPMI-8226: 159.9;RPTEC TERT1: 155.8 +PRODH HSPOX2, PIG6, PRODH1, PRODH2, TP53I6 ENSG00000100033 Proline dehydrogenase 1 22 18912777-18936553 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020361 Uncertain Cervical cancer:1.54e-4 (favourable) Tissue enhanced Tissue enhanced small intestine: 25.2 duodenum: 5.7 Cell line enriched 6 RPTEC TERT1: 28.5 +PPM1F CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2 ENSG00000100034 Protein phosphatase, Mg2+/Mn2+ dependent 1F 22 21919420-21952837 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030989, HPA030990 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:6.03e-5 (unfavourable) Expressed in all Expressed in all placenta: 38.9 Expressed in all +SLC35E4 ENSG00000100036 Solute carrier family 35 member E4 22 30635652-30669016 Predicted membrane proteins, Transporters Evidence at transcript level HPA049558 Approved Approved Cytosol Mixed Tissue enhanced testis: 17.6 cerebral cortex: 5.1 Mixed +TOP3B ENSG00000100038 Topoisomerase (DNA) III beta 22 21957025-21982816 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA069678 Approved Vesicles Not detected Mixed spleen: 18.9 Expressed in all +CRYBB3 CRYB3 ENSG00000100053 Crystallin beta B3 22 25199850-25207363 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055840 Supported Mixed Mixed thyroid gland: 2.1 Cell line enhanced HaCaT: 1.2;HEK 293: 1.3 +CYTH4 CYT4, cytohesin-4, PSCD4 ENSG00000100055 Cytohesin 4 22 37282027-37315345 Predicted intracellular proteins Evidence at protein level HPA071573 Approved Renal cancer:2.41e-8 (unfavourable) Expressed in all Tissue enhanced appendix: 89.2 spleen: 69.8 Cell line enhanced HL-60: 27.2;HMC-1: 119.3;THP-1: 62.2 +DGCR14 DGCR13, DGS-H, DGSI, ES2, Es2el ENSG00000100056 DiGeorge syndrome critical region gene 14 22 19130279-19144684 Predicted intracellular proteins Evidence at protein level HPA001221, HPA001222 Enhanced Approved Nucleoplasm Expressed in all Mixed testis: 1.9 Mixed +MFNG ENSG00000100060 MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 22 37469063-37486401 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048936, HPA056479 Approved Uncertain Actin filaments Renal cancer:3.31e-5 (unfavourable), Endometrial cancer:1.65e-4 (favourable), Colorectal cancer:5.12e-4 (unfavourable) Expressed in all Mixed lymph node: 68.5 Cell line enhanced HL-60: 153.4;HMC-1: 213.3;HUVEC TERT2: 166.4;U-937: 134.0 +CARD10 BIMP1, CARMA3 ENSG00000100065 Caspase recruitment domain family member 10 22 37490362-37519542 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029359, HPA055612 Approved Approved Vesicles
Intermediate filaments
Cytosol Liver cancer:7.73e-6 (unfavourable), Endometrial cancer:3.47e-4 (favourable) Expressed in all Mixed small intestine: 39.9 Cell line enhanced U-2197: 76.9 +LRP5L DKFZp434O0213 ENSG00000100068 LDL receptor related protein 5 like 22 25351418-25405377 Predicted intracellular proteins Evidence at transcript level HPA028717 Uncertain Approved Nucleoplasm Urothelial cancer:6.93e-6 (favourable) Expressed in all Mixed thyroid gland: 9.7 Mixed +SLC25A1 CTP, SLC20A3 ENSG00000100075 Solute carrier family 25 member 1 22 19175575-19178830 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Expressed in all Expressed in all duodenum: 112.7 Expressed in all +GRK3 ADRBK2, BARK2 ENSG00000100077 G protein-coupled receptor kinase 3 22 25564849-25729294 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000804 Uncertain Approved Nucleus
Plasma membrane Urothelial cancer:1.29e-4 (favourable) Expressed in all Mixed adipose tissue: 32.7 Cell line enhanced HDLM-2: 40.3;SH-SY5Y: 39.9 +PLA2G3 GIII-SPLA2 ENSG00000100078 Phospholipase A2 group III 22 31134809-31140607 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA021016 Uncertain Head and neck cancer:4.47e-4 (favourable) Mixed Tissue enhanced esophagus: 4.4;lung: 3.6;skin: 10.2 parathyroid gland: 1.5 Group enriched 6 AF22: 14.3;AN3-CA: 13.6;NTERA-2: 7.5;SCLC-21H: 13.2 +LGALS2 HL14 ENSG00000100079 Galectin 2 22 37570246-37582616 Predicted intracellular proteins Evidence at protein level HPA003536, CAB025198 Enhanced Approved Nucleoplasm
Mitochondria Expressed in all Tissue enhanced gallbladder: 537.1;small intestine: 225.0 kidney: 155.6 Group enriched 13 CACO-2: 92.0;Hep G2: 42.9 +GGA1 ENSG00000100083 Golgi associated, gamma adaptin ear containing, ARF binding protein 1 22 37608475-37633564 Predicted intracellular proteins Evidence at protein level HPA048280, HPA051016 Supported Supported Nucleoplasm
Vesicles Pancreatic cancer:4.86e-4 (favourable), Liver cancer:6.29e-4 (unfavourable) Expressed in all Expressed in all testis: 199.2 Expressed in all +HIRA DGCR1, TUP1, TUPLE1 ENSG00000100084 Histone cell cycle regulator 22 19330698-19447450 Predicted intracellular proteins Evidence at protein level CAB039243, CAB039244, HPA050714, HPA052902 Enhanced Enhanced Nucleoplasm Renal cancer:5.18e-6 (favourable), Pancreatic cancer:3.97e-4 (favourable), Ovarian cancer:8.11e-4 (favourable) Expressed in all Expressed in all thyroid gland: 93.8 Expressed in all +SH3BP1 ARHGAP43 ENSG00000100092 SH3 domain binding protein 1 22 37634654-37666932 Predicted intracellular proteins Evidence at protein level HPA000757 Enhanced Approved Cytosol Renal cancer:3.48e-7 (unfavourable), Stomach cancer:3.39e-4 (favourable), Liver cancer:9.55e-4 (unfavourable) Expressed in all Mixed spleen: 17.9 Mixed +SEZ6L ENSG00000100095 Seizure related 6 homolog like 22 26169474-26383597 Predicted membrane proteins Evidence at protein level HPA045135 Approved Vesicles Group enriched Tissue enriched 7 cerebral cortex: 89.2 adrenal gland: 13.6 Group enriched 8 SCLC-21H: 49.2;SH-SY5Y: 11.9 +LGALS1 GBP ENSG00000100097 Galectin 1 22 37675608-37679806 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000646, HPA000687, HPA001130, CAB002157 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:1.18e-10 (unfavourable), Endometrial cancer:2.36e-5 (favourable), Liver cancer:3.06e-4 (unfavourable), Urothelial cancer:5.10e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 1727.9 Expressed in all +HPS4 BLOC3S2, KIAA1667, LE ENSG00000100099 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 22 26443423-26483837 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB033106, HPA050189 Approved Approved Centrosome Expressed in all Expressed in all testis: 24.2 Expressed in all +PIK3IP1 HGFL, MGC17330 ENSG00000100100 Phosphoinositide-3-kinase interacting protein 1 22 31281593-31292534 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Urothelial cancer:3.80e-4 (favourable) Expressed in all Expressed in all lymph node: 121.1 Cell line enhanced U-698: 23.5 +SRRD HC/HCC, SRR1L ENSG00000100104 SRR1 domain containing 22 26483877-26494658 Predicted intracellular proteins Evidence at protein level HPA002945 Uncertain Approved Cytosol Liver cancer:2.16e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 17.7 Expressed in all +PATZ1 dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG ENSG00000100105 POZ/BTB and AT hook containing zinc finger 1 22 31325804-31346232 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047893, HPA048315 Approved Supported Nucleoplasm Renal cancer:8.54e-8 (favourable), Urothelial cancer:7.79e-6 (favourable), Glioma:6.53e-5 (favourable), Lung cancer:8.71e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 40.4 Expressed in all +TRIOBP DFNB28, HRIHFB2122, KIAA1662, TAP68, Tara ENSG00000100106 TRIO and F-actin binding protein 22 37697004-37776556 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003747, HPA019769 Enhanced Cervical cancer:4.29e-4 (favourable) Expressed in all Expressed in all spleen: 65.9 Expressed in all +TFIP11 DKFZP434B194, Spp382, TIP39 ENSG00000100109 Tuftelin interacting protein 11 22 26491225-26512505 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027085 Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 50.0 Expressed in all +GCAT KBL ENSG00000100116 Glycine C-acetyltransferase 22 37807905-37817176 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020460 Uncertain Supported Nucleoplasm
Mitochondria Expressed in all Expressed in all prostate: 30.0 Expressed in all +GGTLC2 GGTL4 ENSG00000100121 Gamma-glutamyltransferase light chain 2 22 22644475-22647903 Predicted intracellular proteins Evidence at protein level HPA045635, HPA047534 Uncertain Not detected Tissue enriched 9 testis: 7.0 small intestine: 0.7 Not detected +CRYBB1 ENSG00000100122 Crystallin beta B1 22 26599278-26618088 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003448, CAB010058 Supported Mixed Tissue enhanced epididymis: 10.9 placenta: 4.5 Cell line enhanced HMC-1: 9.9;Karpas-707: 29.5;RPMI-8226: 53.1 +ANKRD54 LIAR ENSG00000100124 Ankyrin repeat domain 54 22 37830855-37849327 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA071287 Approved Approved Nucleoplasm
Microtubules
Midbody Endometrial cancer:7.38e-5 (favourable), Cervical cancer:2.06e-4 (favourable), Pancreatic cancer:6.16e-4 (favourable) Expressed in all Expressed in all fallopian tube: 35.8 Expressed in all +EIF3L EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025 ENSG00000100129 Eukaryotic translation initiation factor 3 subunit L 22 37848868-37889407 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003028 Approved Approved Nucleus
Nucleoli Renal cancer:6.11e-4 (favourable) Expressed in all Expressed in all breast: 179.8 Expressed in all +SNU13 15.5K, FA-1, NHP2L1, SNRNP15-5, SPAG12, SSFA1 ENSG00000100138 SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5) 22 41673930-41690504 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA029199 Uncertain Expressed in all Expressed in all testis: 168.8 Expressed in all +MICALL1 KIAA1668, MICAL-L1, MIRAB13 ENSG00000100139 MICAL like 1 22 37905657-37942822 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043480, HPA051956 Uncertain Supported Cell Junctions
Microtubule organizing center
Cytosol Liver cancer:3.08e-6 (unfavourable) Expressed in all Expressed in all smooth muscle: 51.2 Expressed in all +POLR2F HRBP14.4, RPB6 ENSG00000100142 RNA polymerase II subunit F 22 37952607-38041915 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA000827, CAB009882 Supported Enhanced Nucleus
Nucleoli fibrillar center Tissue enhanced Expressed in all cerebral cortex: 120.8 Expressed in all +SOX10 DOM, WS2E, WS4 ENSG00000100146 SRY-box 10 22 37970686-37987422 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003171, HPA068898 Enhanced Supported Nucleoplasm Not detected Tissue enhanced cerebral cortex: 56.6;salivary gland: 50.5 breast: 24.0 Group enriched 686 SK-MEL-30: 236.8;WM-115: 425.1 +CCDC134 FLJ22349 ENSG00000100147 Coiled-coil domain containing 134 22 41800679-41826299 Predicted secreted proteins Evidence at protein level HPA003936 Approved Liver cancer:7.42e-7 (unfavourable), Renal cancer:1.36e-5 (favourable), Endometrial cancer:4.09e-4 (favourable) Expressed in all Mixed parathyroid gland: 14.1 Mixed +DEPDC5 DEP.5, KIAA0645 ENSG00000100150 DEP domain containing 5 22 31753951-31907034 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA054969, HPA055619 Uncertain Approved Golgi apparatus Renal cancer:2.46e-5 (favourable), Urothelial cancer:4.86e-5 (favourable) Expressed in all Mixed cerebral cortex: 13.5 Expressed in all +PICK1 dJ1039K5, MGC15204, PRKCABP ENSG00000100151 Protein interacting with PRKCA 1 22 38056311-38075701 Predicted intracellular proteins Evidence at protein level HPA067384, HPA072674 Approved Approved Mitochondria
Cytosol Stomach cancer:5.26e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 53.2 Mixed +TTC28 KIAA1043 ENSG00000100154 Tetratricopeptide repeat domain 28 22 27978014-28679865 Predicted intracellular proteins Evidence at protein level HPA003099 Approved Nucleoli
Mitochondria Renal cancer:5.65e-5 (favourable), Thyroid cancer:1.21e-4 (unfavourable), Lung cancer:4.30e-4 (favourable) Expressed in all Mixed ovary: 20.8 Mixed +SLC16A8 MCT3, REMP ENSG00000100156 Solute carrier family 16 member 8 22 38078134-38084093 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA075017 Supported Approved Intermediate filaments
Focal adhesion sites Mixed Mixed prostate: 3.9 Cell line enhanced BEWO: 4.3;SiHa: 5.2;T-47d: 5.5;U-266/70: 6.4 +CENPM C22orf18, CENP-M, MGC861, Pane1 ENSG00000100162 Centromere protein M 22 41938721-41947164 Predicted intracellular proteins Evidence at protein level HPA042404, HPA056500 Enhanced Enhanced Cytosol Renal cancer:5.99e-7 (unfavourable), Cervical cancer:3.40e-5 (favourable), Liver cancer:5.50e-5 (unfavourable) Expressed in all Tissue enhanced lymph node: 28.6 bone marrow: 17.6 Expressed in all +SEPT3 SEP3 ENSG00000100167 Septin 3 22 41976272-41998221 Predicted intracellular proteins Evidence at protein level HPA003548, CAB017633 Enhanced Approved Nucleoplasm
Plasma membrane
Actin filaments Endometrial cancer:1.78e-4 (unfavourable) Tissue enhanced Tissue enriched 11 cerebral cortex: 234.8 parathyroid gland: 21.5 Cell line enhanced AF22: 26.2;SCLC-21H: 84.0 +SLC5A1 D22S675, NAGT, SGLT1 ENSG00000100170 Solute carrier family 5 member 1 22 32043032-32113029 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB015467, HPA051805, HPA055106 Enhanced Approved Nucleoplasm
Vesicles Renal cancer:6.97e-7 (favourable), Endometrial cancer:2.59e-4 (favourable) Mixed Group enriched 10 duodenum: 505.0;small intestine: 313.4 gallbladder: 40.2 Cell line enhanced CACO-2: 2.1;RPMI-8226: 1.3;SH-SY5Y: 1.0 +SLC5A4 DJ90G24.4, SAAT1, SGLT3 ENSG00000100191 Solute carrier family 5 member 4 22 32218476-32255341 Predicted membrane proteins, Transporters Evidence at transcript level Tissue enriched Group enriched 8 duodenum: 18.0;small intestine: 21.3 lung: 2.3 Cell line enriched 15 SK-MEL-30: 21.9 +KDELR3 ENSG00000100196 KDEL endoplasmic reticulum protein retention receptor 3 22 38468062-38483447 Predicted membrane proteins Evidence at protein level HPA043477, HPA076405 Uncertain Enhanced Endoplasmic reticulum Renal cancer:6.05e-10 (unfavourable), Liver cancer:1.19e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 46.5 Cell line enhanced ASC TERT1: 179.3;fHDF/TERT166: 214.6 +CYP2D6 CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D ENSG00000100197 Cytochrome P450 family 2 subfamily D member 6 22 42126499-42130906 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045223 Enhanced Approved Golgi apparatus Tissue enriched Group enriched 5 duodenum: 3.7;liver: 10.0;small intestine: 13.0 testis: 1.7 Cell line enhanced Hep G2: 1.2;HMC-1: 2.2;REH: 1.4;U-266/70: 1.3 +DDX17 P72 ENSG00000100201 DEAD-box helicase 17 22 38483440-38507660 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB024908, HPA063142 Enhanced Enhanced Nuclear speckles Lung cancer:6.06e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 336.0 Expressed in all +DMC1 LIM15 ENSG00000100206 DNA meiotic recombinase 1 22 38518949-38570286 Predicted intracellular proteins Evidence at protein level HPA001232, CAB015397 Enhanced Approved Nucleoplasm Mixed Tissue enriched 5 testis: 22.0 endometrium: 4.0 Cell line enhanced HDLM-2: 23.2 +TCF20 AR1, SPBP ENSG00000100207 Transcription factor 20 22 42160013-42343616 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017849, HPA036786 Approved Supported Nucleoplasm
Nuclear bodies Colorectal cancer:1.88e-4 (favourable), Liver cancer:4.89e-4 (unfavourable) Expressed in all Mixed thyroid gland: 3.7 Mixed +HSCB DNAJC20, HSC20, Jac1 ENSG00000100209 HscB mitochondrial iron-sulfur cluster cochaperone 22 28742031-28757515 Predicted intracellular proteins Evidence at protein level HPA018447, HPA031518 Uncertain Supported Nucleus
Mitochondria
Cytosol Endometrial cancer:3.78e-4 (favourable), Urothelial cancer:8.38e-4 (favourable) Expressed in all Expressed in all adrenal gland: 13.2 Expressed in all +CBY1 C22orf2, Cby, Chibby, PGEA1, PIGEA-14, PIGEA14 ENSG00000100211 Chibby family member 1, beta catenin antagonist 22 38656636-38673854 Predicted intracellular proteins Evidence at protein level Endometrial cancer:5.22e-5 (favourable) Expressed in all Expressed in all fallopian tube: 95.7 Expressed in all +TOMM22 TOM22 ENSG00000100216 Translocase of outer mitochondrial membrane 22 22 38681948-38685421 Predicted membrane proteins Evidence at protein level HPA003037 Enhanced Enhanced Mitochondria Liver cancer:2.90e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 32.7 Expressed in all +RSPH14 RTDR1 ENSG00000100218 Radial spoke head 14 homolog 22 23059415-23145021 Predicted intracellular proteins Evidence at protein level HPA018420, HPA050425 Approved Uncertain Nucleoli Renal cancer:4.04e-4 (favourable) Tissue enhanced Tissue enhanced fallopian tube: 18.3;testis: 29.1 kidney: 7.3 Cell line enhanced RPTEC TERT1: 3.1;SCLC-21H: 3.2;U-266/70: 3.6 +XBP1 XBP2 ENSG00000100219 X-box binding protein 1 22 28794555-28800597 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Not detected Expressed in all breast: 918.6 Expressed in all +RTCB C22orf28, FAAP, HSPC117 ENSG00000100220 RNA 2',3'-cyclic phosphate and 5'-OH ligase 22 32387582-32412255 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000535, HPA001103 Enhanced Supported Nucleoplasm
Vesicles
Cytosol Renal cancer:4.25e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 104.2 Expressed in all +JOSD1 KIAA0063 ENSG00000100221 Josephin domain containing 1 22 38685543-38701556 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001168 Uncertain Liver cancer:4.50e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 56.4 Expressed in all +FBXO7 Fbx, FBX7, PARK15 ENSG00000100225 F-box protein 7 22 32474676-32498829 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA032113, HPA032114, CAB034296 Uncertain Supported Nucleus
Cytosol Renal cancer:2.66e-10 (favourable), Colorectal cancer:1.08e-5 (favourable) Expressed in all Expressed in all thyroid gland: 225.1 Expressed in all +GTPBP1 GP-1, HSPC018 ENSG00000100226 GTP binding protein 1 22 38705723-38738299 Predicted intracellular proteins Evidence at protein level HPA003166, HPA064702 Approved Approved Nuclear bodies
Golgi apparatus
Cytosol Liver cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 65.0 Expressed in all +POLDIP3 KIAA1649, PDIP46 ENSG00000100227 DNA polymerase delta interacting protein 3 22 42583721-42614962 Predicted intracellular proteins Evidence at protein level HPA018419, HPA048790 Approved Enhanced Nuclear speckles
Cytoplasmic bodies Renal cancer:3.36e-4 (favourable), Glioma:6.67e-4 (favourable) Expressed in all Expressed in all ovary: 109.8 Expressed in all +RAB36 ENSG00000100228 RAB36, member RAS oncogene family 22 23145326-23164350 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059631 Approved Vesicles Renal cancer:4.55e-4 (favourable) Mixed Tissue enhanced fallopian tube: 52.9;thyroid gland: 29.6 testis: 10.4 Cell line enhanced SCLC-21H: 20.4 +TIMP3 SFD ENSG00000100234 TIMP metallopeptidase inhibitor 3 22 32801701-32863043 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Ovarian cancer:1.90e-5 (unfavourable), Renal cancer:1.50e-4 (favourable) Mixed Tissue enhanced placenta: 1439.9 adipose tissue: 729.9 Cell line enhanced BJ: 988.6;fHDF/TERT166: 830.6;WM-115: 879.2 +PPP6R2 dJ579N16.1, KIAA0685, SAP190, SAPS2 ENSG00000100239 Protein phosphatase 6 regulatory subunit 2 22 50343304-50445090 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030656, CAB034919 Uncertain Supported Vesicles
Cytosol Endometrial cancer:1.70e-5 (favourable), Pancreatic cancer:7.51e-4 (favourable) Expressed in all Expressed in all testis: 65.3 Expressed in all +SBF1 DENND7A, MTMR5 ENSG00000100241 SET binding factor 1 22 50445000-50475024 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA074004 Approved Nuclear bodies Head and neck cancer:3.46e-5 (favourable) Expressed in all Expressed in all testis: 84.1 Expressed in all +SUN2 UNC84B ENSG00000100242 Sad1 and UNC84 domain containing 2 22 38734725-38794143 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001209 Supported Supported Nuclear membrane Expressed in all Expressed in all lymph node: 118.9 Expressed in all +CYB5R3 DIA1 ENSG00000100243 Cytochrome b5 reductase 3 22 42617840-42649568 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001566 Approved Enhanced Endoplasmic reticulum Liver cancer:2.13e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 339.4 Expressed in all +DNAL4 dJ327J16, PIG27 ENSG00000100246 Dynein axonemal light chain 4 22 38778508-38794198 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003647 Approved Approved Nucleus
Nucleoli
Centrosome
Cytosol Renal cancer:1.20e-6 (favourable) Expressed in all Expressed in all testis: 59.7 Mixed +C22orf31 bK747E2.1, HS747E2A ENSG00000100249 Chromosome 22 open reading frame 31 22 29058672-29061844 Predicted intracellular proteins Evidence at transcript level HPA000604 Uncertain Not detected Tissue enriched 12 testis: 13.9 epididymis: 1.1 Not detected +MIOX ALDRL6 ENSG00000100253 Myo-inositol oxygenase 22 50486784-50490648 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039451, HPA039562 Enhanced Renal cancer:2.60e-6 (favourable) Tissue enriched Tissue enriched 30 kidney: 821.5 thyroid gland: 26.9 Cell line enhanced HDLM-2: 23.3;Karpas-707: 9.3;U-266/70: 5.9 +LMF2 TMEM112B, TMEM153 ENSG00000100258 Lipase maturation factor 2 22 50502949-50507691 Predicted membrane proteins Evidence at protein level HPA062626 Approved Approved Centrosome Cervical cancer:3.47e-4 (favourable) Expressed in all Expressed in all pancreas: 38.1 Expressed in all +RHBDD3 C22orf3, PTAG ENSG00000100263 Rhomboid domain containing 3 22 29259852-29268209 Predicted membrane proteins Evidence at protein level HPA043979 Approved Approved Microtubules Endometrial cancer:2.67e-6 (favourable), Renal cancer:2.24e-4 (unfavourable) Expressed in all Mixed testis: 10.5 Mixed +PACSIN2 SDPII ENSG00000100266 Protein kinase C and casein kinase substrate in neurons 2 22 42835412-43015145 Predicted intracellular proteins Evidence at protein level HPA049854, HPA056520 Enhanced Supported Nuclear speckles
Vesicles
Plasma membrane
Cytosol Renal cancer:1.09e-13 (favourable), Liver cancer:7.33e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 95.3 Expressed in all +TTLL1 C22orf7 ENSG00000100271 Tubulin tyrosine ligase like 1 22 43039644-43089428 Predicted intracellular proteins Evidence at transcript level HPA048392 Approved Approved Nucleoli
Mitochondria Liver cancer:2.34e-5 (unfavourable), Renal cancer:1.68e-4 (favourable), Endometrial cancer:1.85e-4 (favourable) Expressed in all Mixed testis: 20.2 Mixed +RASL10A RRP22 ENSG00000100276 RAS like family 10 member A 22 29312933-29319679 Predicted intracellular proteins Evidence at protein level HPA056169 Approved Tissue enhanced Tissue enriched 15 cerebral cortex: 33.5 breast: 2.2 Cell line enhanced HEK 293: 1.4;NB-4: 1.5;U-2 OS: 1.1;U-266/70: 2.0 +AP1B1 ADTB1, AP105A, BAM22, CLAPB2 ENSG00000100280 Adaptor related protein complex 1 beta 1 subunit 22 29327680-29423179 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065226, HPA068520 Approved Supported Golgi apparatus
Vesicles Renal cancer:7.24e-6 (favourable), Liver cancer:5.55e-5 (unfavourable), Cervical cancer:4.81e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 104.2 Expressed in all +HMGXB4 HMG2L1, THC211630 ENSG00000100281 HMG-box containing 4 22 35257452-35295807 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000725 Approved Colorectal cancer:3.24e-5 (favourable), Pancreatic cancer:1.16e-4 (unfavourable), Liver cancer:4.79e-4 (unfavourable) Expressed in all Expressed in all endometrium: 18.8 Expressed in all +TOM1 ENSG00000100284 Target of myb1 membrane trafficking protein 22 35299275-35347994 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA000818, HPA001749 Approved Approved Plasma membrane
Microtubule organizing center
Cytosol Endometrial cancer:2.20e-5 (favourable), Renal cancer:3.72e-5 (favourable) Expressed in all Expressed in all esophagus: 54.6 Expressed in all +NEFH ENSG00000100285 Neurofilament heavy 22 29480230-29491390 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB007786, HPA061615 Enhanced Approved Nucleoli
Cytosol Breast cancer:2.33e-6 (favourable) Group enriched Tissue enriched 11 prostate: 405.8 cerebral cortex: 37.3 Cell line enriched 6 SiHa: 193.4 +CHKB CHETK, CHKL ENSG00000100288 Choline kinase beta 22 50578949-50601455 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018797 Approved Approved Cytosol Renal cancer:1.56e-5 (unfavourable), Cervical cancer:4.66e-4 (favourable) Expressed in all Mixed testis: 15.1 Mixed +BIK NBK ENSG00000100290 BCL2 interacting killer 22 43110748-43129712 Predicted membrane proteins Evidence at protein level HPA051360 Approved Renal cancer:7.45e-5 (favourable) Mixed Mixed lymph node: 14.0 Cell line enhanced A-431: 77.8;U-698: 117.1 +HMOX1 bK286B10, HO-1 ENSG00000100292 Heme oxygenase 1 22 35380361-35394214 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000635, CAB017444 Enhanced Uncertain Golgi apparatus
Plasma membrane Liver cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all spleen: 428.5 Cell line enhanced BEWO: 701.9;U-138 MG: 414.7;U-87 MG: 399.9 +MCAT fabD, FASN2C, MCT, MCT1, MT, NET62 ENSG00000100294 Malonyl-CoA-acyl carrier protein transacylase 22 43132206-43143394 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003122, HPA035471 Approved Supported Mitochondria Renal cancer:2.18e-4 (favourable), Stomach cancer:3.89e-4 (favourable), Endometrial cancer:5.53e-4 (favourable) Expressed in all Expressed in all fallopian tube: 23.0 Expressed in all +THOC5 C22orf19, Fmip, fSAP79, KIAA0983, PK1.3 ENSG00000100296 THO complex 5 22 29505879-29555216 Predicted intracellular proteins Evidence at protein level HPA048402 Supported Nucleoplasm Liver cancer:3.76e-6 (unfavourable), Renal cancer:3.65e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 43.1 Expressed in all +MCM5 CDC46 ENSG00000100297 Minichromosome maintenance complex component 5 22 35400063-35425430 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000101, HPA000845, HPA052880 Enhanced Enhanced Nucleoplasm Cervical cancer:2.81e-6 (favourable), Renal cancer:3.58e-5 (unfavourable), Liver cancer:1.78e-4 (unfavourable), Lung cancer:3.95e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 88.5 Expressed in all +APOBEC3H ARP10 ENSG00000100298 Apolipoprotein B mRNA editing enzyme catalytic subunit 3H 22 39097224-39104067 Predicted intracellular proteins Evidence at protein level HPA021492 Approved Renal cancer:8.73e-12 (unfavourable), Urothelial cancer:8.43e-7 (favourable), Cervical cancer:1.20e-4 (favourable) Mixed Mixed epididymis: 4.8 Cell line enhanced HDLM-2: 2.7;Karpas-707: 5.3;U-266/70: 3.7 +ARSA ENSG00000100299 Arylsulfatase A 22 50622754-50628173 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005554, CAB025183 Enhanced Uncertain Golgi apparatus
Cytosol Endometrial cancer:2.96e-5 (favourable) Expressed in all Expressed in all testis: 37.4 Cell line enhanced Karpas-707: 58.2 +TSPO BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS ENSG00000100300 Translocator protein 22 43151514-43163242 Cancer-related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB011232, HPA046260 Uncertain Approved Vesicles
Mitochondria
Cytosol Liver cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 300.6 Mixed +RASD2 MGC:4834, Rhes, TEM2 ENSG00000100302 RASD family member 2 22 35540868-35554001 Predicted intracellular proteins Evidence at protein level HPA005839 Enhanced Approved Plasma membrane
Cytosol Renal cancer:2.22e-5 (unfavourable) Mixed Tissue enhanced seminal vesicle: 32.2 epididymis: 18.5 Cell line enhanced SK-BR-3: 4.2;U-2 OS: 3.3;U-87 MG: 3.9 +TTLL12 KIAA0153 ENSG00000100304 Tubulin tyrosine ligase like 12 22 43166622-43187133 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003054, CAB046029 Approved Approved Plasma membrane
Cytosol Liver cancer:2.84e-4 (unfavourable) Expressed in all Expressed in all esophagus: 74.3 Expressed in all +CBX7 ENSG00000100307 Chromobox 7 22 39120167-39152674 Predicted intracellular proteins Evidence at protein level CAB011574, HPA048677, HPA056480 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:2.45e-5 (favourable), Pancreatic cancer:1.04e-4 (favourable), Cervical cancer:3.63e-4 (favourable), Colorectal cancer:3.73e-4 (unfavourable), Breast cancer:6.18e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 81.6 Cell line enhanced HDLM-2: 34.6 +PDGFB SIS, SSV ENSG00000100311 Platelet derived growth factor subunit B 22 39223359-39244751 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB011604, HPA011972, CAB018341 Supported Approved Vesicles Lung cancer:3.67e-5 (unfavourable) Expressed in all Tissue enhanced placenta: 59.7 lung: 28.6 Cell line enhanced EFO-21: 65.2;HUVEC TERT2: 45.3;SK-BR-3: 40.1;TIME: 55.5 +ACR ENSG00000100312 Acrosin 22 50738196-50745334 Enzymes, Predicted secreted proteins Evidence at protein level HPA048687 Enhanced Not detected Tissue enriched 57 testis: 58.0 spleen: 1.0 Not detected +CABP7 MGC57793 ENSG00000100314 Calcium binding protein 7 22 29720084-29731839 Predicted membrane proteins Evidence at protein level HPA016439 Uncertain Tissue enhanced Tissue enhanced adrenal gland: 2.5;cerebral cortex: 3.4 small intestine: 1.4 Group enriched 13 HEL: 9.4;SCLC-21H: 11.7;SH-SY5Y: 3.3;U-2 OS: 3.4 +RPL3 L3 ENSG00000100316 Ribosomal protein L3 22 39312882-39320389 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA003365, HPA055361 Uncertain Supported Nucleoli
Cytosol Expressed in all Expressed in all ovary: 5675.2 Expressed in all +ZMAT5 SNRNP20, ZC3H19 ENSG00000100319 Zinc finger matrin-type 5 22 29730956-29767011 Predicted intracellular proteins Evidence at protein level HPA004858 Approved Supported Nucleoplasm Expressed in all Expressed in all fallopian tube: 35.5 Expressed in all +RBFOX2 FOX-2, HNRBP2, HRNBP2, RBM9 ENSG00000100320 RNA binding protein, fox-1 homolog 2 22 35738736-36028425 Predicted intracellular proteins Evidence at protein level HPA006240 Enhanced Supported Nucleoplasm Expressed in all Mixed endometrium: 108.5 Expressed in all +SYNGR1 ENSG00000100321 Synaptogyrin 1 22 39349925-39385588 Predicted membrane proteins Evidence at protein level HPA029673, CAB034277 Enhanced Supported Cytosol Renal cancer:4.98e-7 (favourable), Pancreatic cancer:2.41e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 175.4 Mixed +TAB1 MAP3K7IP1 ENSG00000100324 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 22 39399741-39437060 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032328, HPA039988, HPA057104 Approved Enhanced Nuclear speckles
Cytosol Expressed in all Expressed in all cerebral cortex: 23.1 Expressed in all +ASCC2 ASC1p100, DKFZp586O0223, FLJ21588 ENSG00000100325 Activating signal cointegrator 1 complex subunit 2 22 29788608-29838304 Predicted intracellular proteins Evidence at protein level HPA001439, HPA052879 Approved Approved Nucleus
Focal adhesion sites
Cytosol Expressed in all Expressed in all testis: 46.0 Expressed in all +MTMR3 FYVE-DSP1, KIAA0371, ZFYVE10 ENSG00000100330 Myotubularin related protein 3 22 29883155-30030866 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034515, HPA034516, HPA061399 Uncertain Supported Nucleoplasm
Cytosol Mixed Expressed in all bone marrow: 52.3 Expressed in all +MIEF1 FLJ20232, MiD51, SMCR7L ENSG00000100335 Mitochondrial elongation factor 1 22 39499432-39518132 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA061059 Approved Intermediate filaments
Mitochondria Renal cancer:3.96e-5 (favourable) Expressed in all Expressed in all testis: 22.1 Expressed in all +APOL4 APOLIV ENSG00000100336 Apolipoprotein L4 22 36189124-36204840 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049797, HPA055435 Approved Supported Vesicles Urothelial cancer:2.40e-6 (favourable), Renal cancer:2.00e-5 (unfavourable), Ovarian cancer:3.45e-4 (favourable) Expressed in all Mixed prostate: 26.7 Cell line enhanced BEWO: 19.1;HDLM-2: 103.0;K-562: 21.3;SCLC-21H: 56.9 +PNPLA5 dJ388M5.4, GS2L ENSG00000100341 Patatin like phospholipase domain containing 5 22 43879678-43892013 Predicted intracellular proteins Evidence at transcript level HPA050409, HPA054211 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 1.1;epididymis: 2.1 skin: 0.7 Cell line enhanced NTERA-2: 1.4;RPMI-8226: 1.9;SCLC-21H: 1.0 +APOL1 APOL ENSG00000100342 Apolipoprotein L1 22 36253010-36267530 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018885, CAB056156 Supported Renal cancer:7.43e-6 (unfavourable), Urothelial cancer:2.01e-5 (favourable), Lung cancer:5.35e-4 (unfavourable) Expressed in all Expressed in all liver: 116.1 Cell line enhanced EFO-21: 233.1;HDLM-2: 156.1;RT4: 120.9 +PNPLA3 adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon ENSG00000100344 Patatin like phospholipase domain containing 3 22 43923739-43964488 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA058058 Approved Approved Nucleoli
Mitochondria
Cytosol Tissue enhanced Tissue enhanced liver: 16.2 kidney: 4.7 Mixed +MYH9 DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA ENSG00000100345 Myosin heavy chain 9 22 36281281-36388018 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001644, CAB015386, HPA064783 Enhanced Supported Plasma membrane
Actin filaments
Cytosol Expressed in all Expressed in all spleen: 308.5 Expressed in all +CACNA1I Cav3.3 ENSG00000100346 Calcium voltage-gated channel subunit alpha1 I 22 39570753-39689737 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 4.7;thyroid gland: 2.7 adrenal gland: 2.3 Cell line enhanced SK-BR-3: 1.4;T-47d: 1.0 +SAMM50 CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W ENSG00000100347 SAMM50 sorting and assembly machinery component 22 43955421-44010531 Predicted intracellular proteins, Transporters Evidence at protein level HPA034537 Enhanced Enhanced Mitochondria Renal cancer:4.43e-8 (favourable), Endometrial cancer:2.63e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 242.2 Expressed in all +TXN2 MT-TRX ENSG00000100348 Thioredoxin 2 22 36467036-36482030 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000994, CAB008681 Approved Enhanced Mitochondria Renal cancer:1.17e-6 (favourable), Prostate cancer:2.04e-4 (favourable) Expressed in all Expressed in all adrenal gland: 145.2 Expressed in all +FOXRED2 ERFAD, FLJ23322 ENSG00000100350 FAD dependent oxidoreductase domain containing 2 22 36487190-36507101 Predicted secreted proteins Evidence at protein level HPA031611, HPA031612 Approved Cervical cancer:4.86e-5 (favourable), Thyroid cancer:9.32e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 30.8 Cell line enhanced SiHa: 155.2 +GRAP2 GADS, GRBLG, GrbX, Grf40, Mona ENSG00000100351 GRB2-related adaptor protein 2 22 39901082-39973721 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005788, CAB022073 Enhanced Mixed Tissue enhanced lymph node: 18.0 spleen: 12.8 Group enriched 8 HDLM-2: 22.1;HEL: 40.9;K-562: 39.9;MOLT-4: 98.1 +EIF3D eIF3-p66, eIF3-zeta, eIF3d, EIF3S7 ENSG00000100353 Eukaryotic translation initiation factor 3 subunit D 22 36510850-36529436 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045882, HPA063330, HPA066216 Approved Supported Cytosol Liver cancer:8.10e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 256.0 Expressed in all +TNRC6B KIAA1093 ENSG00000100354 Trinucleotide repeat containing 6B 22 40044817-40335808 Predicted intracellular proteins Evidence at protein level HPA003180 Approved Expressed in all Mixed testis: 27.6 Expressed in all +SGSM3 DJ1042K10.2, RabGAP-5, RABGAP5, RUSC3, RUTBC3 ENSG00000100359 Small G protein signaling modulator 3 22 40370591-40410289 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048980 Approved Supported Golgi apparatus Endometrial cancer:4.47e-5 (favourable) Expressed in all Expressed in all stomach: 75.9 Expressed in all +IFT27 BBS19, RABL4, RAYL ENSG00000100360 Intraflagellar transport 27 22 36758202-36776256 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018418 Uncertain Approved Nucleoplasm
Mitochondria Endometrial cancer:1.91e-4 (favourable), Urothelial cancer:5.55e-4 (favourable) Expressed in all Expressed in all fallopian tube: 57.4 Cell line enhanced U-138 MG: 156.6 +PVALB D22S749 ENSG00000100362 Parvalbumin 22 36800684-36819479 Predicted intracellular proteins Evidence at protein level CAB002515, HPA048536 Enhanced Approved Approved Nucleoplasm
Nucleoli
Cell Junctions Group enriched Tissue enriched 13 parathyroid gland: 547.2 kidney: 43.5 Cell line enriched 144 RPMI-8226: 558.1 +KIAA0930 bK268H5.C22.1, C22orf9 ENSG00000100364 KIAA0930 22 45190338-45240769 Predicted intracellular proteins Evidence at protein level HPA038091 Uncertain Approved Nuclear membrane
Mitochondria Liver cancer:6.90e-8 (unfavourable), Renal cancer:8.95e-7 (unfavourable), Endometrial cancer:9.22e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 76.2 Cell line enhanced THP-1: 220.8 +NCF4 p40phox, SH3PXD4 ENSG00000100365 Neutrophil cytosolic factor 4 22 36860988-36878015 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010146, HPA036156, HPA057975 Enhanced Supported Cytosol Renal cancer:7.06e-8 (unfavourable) Expressed in all Tissue enhanced bone marrow: 119.9 appendix: 59.4 Cell line enhanced HEL: 78.2;HMC-1: 349.8;NB-4: 93.8;RPMI-8226: 102.1;THP-1: 92.9 +CSF2RB CD131, IL3RB, IL5RB ENSG00000100368 Colony stimulating factor 2 receptor beta common subunit 22 36913628-36940449 CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA078677 Approved Golgi apparatus Head and neck cancer:7.47e-5 (favourable) Expressed in all Tissue enhanced appendix: 89.7 tonsil: 57.2 Group enriched 7 HEL: 95.8;HMC-1: 281.8 +SLC25A17 PMP34 ENSG00000100372 Solute carrier family 25 member 17 22 40769630-40819399 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA052708, HPA060972 Approved Supported Peroxisomes Expressed in all Expressed in all ovary: 24.1 Expressed in all +UPK3A UPK3 ENSG00000100373 Uroplakin 3A 22 45284982-45295874 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA018407, HPA018415 Enhanced Uncertain Nuclear membrane
Nuclear bodies Group enriched Group enriched 7 parathyroid gland: 13.0;prostate: 35.0;skeletal muscle: 12.6;urinary bladder: 15.4 thyroid gland: 2.6 Group enriched 6 Hep G2: 20.8;RT4: 40.2 +FAM118A bK268H5.C22.4, C22orf8, FLJ20635 ENSG00000100376 Family with sequence similarity 118 member A 22 45308968-45341955 Predicted intracellular proteins Evidence at protein level HPA003902 Uncertain Approved Intermediate filaments
Cytosol Renal cancer:1.87e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 76.1 Expressed in all +KCTD17 FLJ12242 ENSG00000100379 Potassium channel tetramerization domain containing 17 22 37051736-37063390 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018459 Uncertain Renal cancer:5.13e-12 (unfavourable), Liver cancer:3.59e-5 (unfavourable), Pancreatic cancer:4.22e-5 (favourable) Expressed in all Tissue enhanced cerebral cortex: 55.9 testis: 35.3 Mixed +ST13 FAM10A1, HIP, HSPABP1, P48, SNC6 ENSG00000100380 Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 22 40824535-40857022 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043233, HPA046412, HPA047114, HPA047116 Enhanced Enhanced Cytosol Renal cancer:3.10e-4 (favourable), Head and neck cancer:5.23e-4 (unfavourable) Expressed in all Expressed in all ovary: 653.8 Expressed in all +IL2RB CD122, IL15RB ENSG00000100385 Interleukin 2 receptor subunit beta 22 37125838-37175054 Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA062657 Enhanced Renal cancer:3.50e-7 (unfavourable), Endometrial cancer:3.18e-5 (favourable), Colorectal cancer:6.76e-4 (favourable) Expressed in all Tissue enhanced placenta: 52.7;spleen: 67.1 lymph node: 39.8 Cell line enriched 10 HDLM-2: 476.9 +RBX1 BA554C12.1, RNF75, ROC1 ENSG00000100387 Ring-box 1 22 40951347-40973309 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003038 Supported Nucleoplasm Ovarian cancer:6.63e-4 (favourable) Expressed in all Expressed in all epididymis: 70.6 Expressed in all +EP300 KAT3B, p300 ENSG00000100393 E1A binding protein p300 22 41091786-41180079 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB000146, HPA003128, HPA004112 Supported Enhanced Nucleoplasm Renal cancer:7.45e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 46.2 Expressed in all +L3MBTL2 dJ756G23.3, DKFZP761I141, H-l(3)mbt-l ENSG00000100395 L3MBTL2 polycomb repressive complex 1 subunit 22 41205205-41231271 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000815 Approved Nucleoplasm Cervical cancer:6.39e-5 (favourable), Endometrial cancer:4.37e-4 (favourable) Expressed in all Expressed in all fallopian tube: 30.2 Expressed in all +CHADL SLRR4B ENSG00000100399 Chondroadherin like 22 41229510-41240934 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005696, HPA024654 Uncertain Lung cancer:1.56e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 28.4 skin: 6.7 Cell line enhanced BEWO: 11.4 +RANGAP1 Fug1, KIAA1835, SD ENSG00000100401 Ran GTPase activating protein 1 22 41245611-41286251 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004293, HPA050110, HPA062034 Enhanced Enhanced Nuclear membrane
Vesicles
Cytosol Liver cancer:1.08e-4 (unfavourable), Stomach cancer:5.39e-4 (favourable) Expressed in all Expressed in all testis: 206.1 Expressed in all +ZC3H7B DKFZp434K0920, FLJ13787, KIAA1031, RoXaN ENSG00000100403 Zinc finger CCCH-type containing 7B 22 41301522-41360147 Predicted intracellular proteins Evidence at protein level HPA001784 Uncertain Uncertain Cytosol Renal cancer:5.43e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 81.6 Expressed in all +PHF5A bK223H9.2, INI, MGC1346, Rds3, SAP14b, SF3b14b, SF3B7 ENSG00000100410 PHD finger protein 5A 22 41459717-41468725 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028885 Supported Enhanced Nucleoplasm Liver cancer:3.02e-8 (unfavourable) Expressed in all Expressed in all lymph node: 39.8 Expressed in all +ACO2 ACONM ENSG00000100412 Aconitase 2 22 41469125-41528989 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001097 Enhanced Supported Supported Mitochondria Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all heart muscle: 308.9 Expressed in all +POLR3H KIAA1665, RPC8 ENSG00000100413 RNA polymerase III subunit H 22 41525804-41544606 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA046787 Approved Supported Nucleoplasm
Vesicles
Centrosome Liver cancer:2.04e-4 (unfavourable), Pancreatic cancer:5.41e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 35.5 Expressed in all +TRMU FLJ10140, MTO2, TRMT ENSG00000100416 TRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 22 46330875-46357340 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000824, HPA035273, HPA043300 Uncertain Supported Nucleoplasm
Mitochondria Renal cancer:5.63e-6 (unfavourable), Liver cancer:3.04e-5 (unfavourable), Pancreatic cancer:6.86e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.0 Expressed in all +PMM1 Sec53 ENSG00000100417 Phosphomannomutase 1 22 41576894-41589890 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030712 Uncertain Endometrial cancer:6.09e-6 (favourable), Pancreatic cancer:2.05e-4 (favourable), Cervical cancer:5.92e-4 (favourable) Expressed in all Expressed in all ovary: 54.9 Expressed in all +DESI1 D15Wsu75e, FAM152B, PPPDE2 ENSG00000100418 Desumoylating isopeptidase 1 22 41598028-41621096 Predicted intracellular proteins Evidence at protein level HPA053415 Approved Approved Cytokinetic bridge
Cytosol Endometrial cancer:7.70e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 29.5 Expressed in all +CERK dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4 ENSG00000100422 Ceramide kinase 22 46684411-46738261 Enzymes, Predicted intracellular proteins Evidence at protein level HPA064699 Approved Vesicles Urothelial cancer:1.58e-4 (unfavourable), Pancreatic cancer:2.35e-4 (favourable), Endometrial cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all small intestine: 34.3 Mixed +BRD1 BRL, BRPF2 ENSG00000100425 Bromodomain containing 1 22 49773283-49827512 Predicted intracellular proteins Evidence at protein level HPA000807, HPA001063 Approved Supported Nuclear speckles Expressed in all Expressed in all testis: 58.5 Expressed in all +ZBED4 KIAA0637 ENSG00000100426 Zinc finger BED-type containing 4 22 49853842-49890078 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045341 Approved Supported Nucleoplasm Expressed in all Expressed in all lymph node: 7.7 Expressed in all +MLC1 KIAA0027, LVM, MLC, VL ENSG00000100427 Megalencephalic leukoencephalopathy with subcortical cysts 1 22 50059391-50085902 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA003040, HPA067533 Enhanced Tissue enriched Tissue enriched 8 cerebral cortex: 180.8 bone marrow: 23.0 Cell line enhanced HL-60: 182.4;NB-4: 133.9;THP-1: 267.0;U-266/70: 101.9;U-266/84: 85.6 +HDAC10 DKFZP761B039 ENSG00000100429 Histone deacetylase 10 22 50245183-50251405 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB045977, HPA056514 Supported Approved Nucleoli fibrillar center Renal cancer:4.74e-11 (unfavourable), Endometrial cancer:2.45e-5 (favourable), Cervical cancer:4.46e-4 (favourable), Pancreatic cancer:9.25e-4 (favourable) Expressed in all Mixed spleen: 9.8 Mixed +KCNK10 K2p10.1, PPP1R97, TREK-2, TREK2 ENSG00000100433 Potassium two pore domain channel subfamily K member 10 14 88180103-88326907 Predicted membrane proteins Evidence at protein level HPA030462 Approved Mixed Tissue enhanced cerebral cortex: 5.6;duodenum: 5.1 small intestine,stomach: 2.7 Cell line enhanced AF22: 1.0;REH: 1.6;SCLC-21H: 3.7 +ABHD4 FLJ12816 ENSG00000100439 Abhydrolase domain containing 4 14 22598237-22613215 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000600 Uncertain Approved Nucleus Expressed in all Expressed in all testis: 62.8 Mixed +KHNYN KIAA0323 ENSG00000100441 KH and NYN domain containing 14 24429286-24441834 Predicted intracellular proteins Evidence at protein level HPA003402 Uncertain Approved Nucleoplasm
Cytosol Cervical cancer:4.38e-4 (unfavourable), Glioma:9.44e-4 (unfavourable) Expressed in all Expressed in all placenta: 47.8 Mixed +FKBP3 FKBP-25, PPIase ENSG00000100442 FK506 binding protein 3 14 45115600-45135319 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000864, CAB012232, CAB012520 Supported Supported Cytosol Expressed in all Expressed in all skeletal muscle: 143.3 Expressed in all +SDR39U1 C14orf124, HCDI ENSG00000100445 Short chain dehydrogenase/reductase family 39U member 1 14 24439766-24442905 Predicted intracellular proteins Evidence at protein level HPA044294 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:2.34e-4 (favourable) Expressed in all Expressed in all adrenal gland: 42.9 Expressed in all +CTSG CG ENSG00000100448 Cathepsin G 14 24573522-24576260 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000110, HPA047737 Enhanced Head and neck cancer:1.57e-4 (favourable), Urothelial cancer:8.91e-4 (unfavourable) Mixed Tissue enriched 84 bone marrow: 3457.0 gallbladder: 41.2 Cell line enriched 6 THP-1: 6055.4 +GZMH CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2 ENSG00000100450 Granzyme H 14 24606480-24609699 Enzymes, Predicted secreted proteins Evidence at protein level HPA029200 Enhanced Renal cancer:1.74e-6 (unfavourable), Endometrial cancer:2.00e-6 (favourable) Expressed in all Tissue enhanced spleen: 35.3 lymph node: 25.3 Not detected +GZMB CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT ENSG00000100453 Granzyme B 14 24630954-24634267 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000376, HPA003418 Enhanced Renal cancer:1.10e-7 (unfavourable), Endometrial cancer:1.58e-5 (favourable), Breast cancer:7.27e-4 (favourable) Expressed in all Tissue enhanced lymph node: 40.1 bone marrow,spleen: 36.2 Cell line enriched 6 HMC-1: 17.4 +RBM23 CAPERbeta, FLJ10482, RNPC4 ENSG00000100461 RNA binding motif protein 23 14 22893206-22919184 Predicted intracellular proteins Evidence at protein level HPA004144 Uncertain Approved Nucleoplasm
Intermediate filaments Renal cancer:8.06e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 144.3 Expressed in all +PRMT5 HRMT1L5, SKB1, SKB1Hs ENSG00000100462 Protein arginine methyltransferase 5 14 22920511-22929585 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005525, CAB012459, HPA064708 Approved Approved Nucleus
Cytosol Liver cancer:4.77e-5 (unfavourable), Urothelial cancer:1.04e-4 (unfavourable), Head and neck cancer:1.82e-4 (unfavourable), Pancreatic cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 72.8 Expressed in all +COCH COCH-5B2, DFNA31, DFNA9 ENSG00000100473 Cochlin 14 30874514-30895065 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA065086 Approved Vesicles Mixed Group enriched 6 pancreas: 94.8;prostate: 79.0;seminal vesicle: 99.1 cervix, uterine: 15.4 Cell line enhanced HEK 293: 92.9;K-562: 114.9;NB-4: 71.8;SCLC-21H: 130.1 +AP4S1 AP47B, CLA20, SPG52 ENSG00000100478 Adaptor related protein complex 4 sigma 1 subunit 14 31025106-31096450 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039963 Approved Supported Vesicles Renal cancer:2.87e-6 (favourable), Lung cancer:7.44e-4 (favourable) Expressed in all Expressed in all testis: 33.1 Expressed in all +POLE2 DPE2 ENSG00000100479 DNA polymerase epsilon 2, accessory subunit 14 49643555-49688422 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA027555 Uncertain Supported Nucleoplasm
Nuclear bodies
Vesicles Expressed in all Mixed bone marrow: 10.7 Mixed +VCPKMT C14orf138, METTL21D, VCP-KMT ENSG00000100483 Valosin containing protein lysine methyltransferase 14 50108632-50116600 Predicted intracellular proteins Evidence at protein level HPA001146, HPA076561 Uncertain Supported Cytosol Lung cancer:2.40e-4 (favourable), Prostate cancer:4.75e-4 (unfavourable), Renal cancer:6.79e-4 (unfavourable) Expressed in all Mixed endometrium: 5.3 Expressed in all +SOS2 ENSG00000100485 SOS Ras/Rho guanine nucleotide exchange factor 2 14 50117120-50231558 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004577, HPA047368, HPA052689 Approved Approved Nucleoplasm
Vesicles Renal cancer:8.48e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 80.7 Expressed in all +CDKL1 KKIALRE ENSG00000100490 Cyclin dependent kinase like 1 14 50329404-50416461 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059605, HPA065919 Uncertain Enhanced Nucleoplasm
Vesicles Mixed Mixed fallopian tube: 34.5 Mixed +NIN ENSG00000100503 Ninein 14 50719763-50831121 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005939, HPA070691 Enhanced Enhanced Nucleus
Nucleoli
Centrosome Expressed in all Mixed lymph node: 47.5 Expressed in all +PYGL ENSG00000100504 Glycogen phosphorylase L 14 50857891-50944736 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000962, HPA004119 Enhanced Supported Plasma membrane
Cytosol Pancreatic cancer:2.63e-4 (unfavourable), Head and neck cancer:5.97e-4 (unfavourable) Expressed in all Mixed adipose tissue: 116.5 Mixed +TRIM9 RNF91, SPRING ENSG00000100505 Tripartite motif containing 9 14 50975262-51096061 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041489 Supported Cytosol Tissue enriched Tissue enriched 11 cerebral cortex: 79.2 gallbladder: 6.9 Cell line enhanced AN3-CA: 29.8;HAP1: 23.6;HDLM-2: 33.8;SCLC-21H: 38.5 +PSMC6 p42 ENSG00000100519 Proteasome 26S subunit, ATPase 6 14 52707172-52728587 Predicted intracellular proteins Evidence at protein level HPA042823 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all thyroid gland: 91.8 Expressed in all +GNPNAT1 FLJ10607, Gpnat1 ENSG00000100522 Glucosamine-phosphate N-acetyltransferase 1 14 52775194-52791668 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044647 Approved Pancreatic cancer:8.52e-5 (unfavourable) Expressed in all Expressed in all liver: 39.4 Expressed in all +DDHD1 KIAA1705, PA-PLA1, SPG28 ENSG00000100523 DDHD domain containing 1 14 53036745-53153282 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049870 Enhanced Mixed Tissue enhanced testis: 34.2 cerebral cortex: 10.6 Expressed in all +CDKN3 CDI1, KAP ENSG00000100526 Cyclin dependent kinase inhibitor 3 14 54396849-54420218 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005285, HPA039311, HPA058874 Enhanced Cytosol Renal cancer:0.00e+0 (unfavourable), Lung cancer:4.52e-4 (unfavourable), Pancreatic cancer:7.46e-4 (unfavourable) Expressed in all Tissue enriched 11 testis: 342.6 lymph node: 31.7 Expressed in all +CNIH1 CNIH, CNIL, TGAM77 ENSG00000100528 Cornichon family AMPA receptor auxiliary protein 1 14 54423560-54441431 Predicted membrane proteins, Transporters Evidence at protein level HPA002544 Approved Approved Vesicles Urothelial cancer:8.95e-4 (unfavourable) Expressed in all Expressed in all liver: 119.4 Expressed in all +CGRRF1 CGR19, RNF197 ENSG00000100532 Cell growth regulator with ring finger domain 1 14 54509812-54539309 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002930 Uncertain Supported Nucleoplasm
Vesicles Renal cancer:2.57e-8 (favourable), Liver cancer:6.84e-4 (unfavourable) Expressed in all Expressed in all testis: 33.8 Expressed in all +ATP6V1D ATP6M, VATD, VMA8 ENSG00000100554 ATPase H+ transporting V1 subunit D 14 67294371-67360265 Predicted intracellular proteins Evidence at protein level HPA031515, HPA057316 Enhanced Approved Nucleoplasm Renal cancer:7.60e-13 (favourable) Expressed in all Expressed in all cerebral cortex: 195.5 Expressed in all +C14orf105 FLJ10650 ENSG00000100557 Chromosome 14 open reading frame 105 14 57469301-57493867 Predicted intracellular proteins Evidence at transcript level HPA029202 Uncertain Nucleus
Cytosol Renal cancer:1.92e-4 (favourable), Liver cancer:5.61e-4 (unfavourable) Tissue enhanced Tissue enhanced fallopian tube: 43.7;gallbladder: 27.1;kidney: 63.6 liver: 11.3 Group enriched 6 A549: 10.7;RPTEC TERT1: 26.1 +PLEK2 ENSG00000100558 Pleckstrin 2 14 67386983-67412200 Predicted intracellular proteins Evidence at protein level HPA001208 Enhanced Uncertain Vesicles
Cytosol Pancreatic cancer:8.26e-5 (unfavourable), Lung cancer:1.58e-4 (unfavourable) Expressed in all Mixed adrenal gland: 43.1 Cell line enhanced A-431: 77.9;CAPAN-2: 81.3;HBEC3-KT: 124.1 +PIGH GPI-H ENSG00000100564 Phosphatidylinositol glycan anchor biosynthesis class H 14 67581955-67600287 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031624 Approved Renal cancer:2.68e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 107.3 Expressed in all +LRRC74A C14orf166B, LRRC74 ENSG00000100565 Leucine rich repeat containing 74A 14 76826372-76870302 Predicted intracellular proteins Evidence at transcript level HPA035094 Uncertain Not detected Tissue enriched 19 testis: 7.1 salivary gland,spleen,stomach: 0.3 Not detected +PSMA3 HC8 ENSG00000100567 Proteasome subunit alpha 3 14 58244831-58272012 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000905 Approved Approved Microtubules
Cytokinetic bridge Thyroid cancer:2.91e-4 (favourable) Expressed in all Expressed in all epididymis: 150.8 Expressed in all +VTI1B VTI2 ENSG00000100568 Vesicle transport through interaction with t-SNAREs 1B 14 67647075-67674831 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044121, HPA048150, HPA060118 Approved Enhanced Golgi apparatus
Vesicles Renal cancer:3.53e-12 (favourable) Expressed in all Expressed in all epididymis: 64.9 Expressed in all +TIMM9 TIM9A ENSG00000100575 Translocase of inner mitochondrial membrane 9 14 58408494-58427614 Predicted intracellular proteins Evidence at protein level HPA002932 Approved Enhanced Mitochondria Ovarian cancer:6.39e-5 (favourable), Liver cancer:9.89e-5 (unfavourable), Breast cancer:8.04e-4 (favourable) Expressed in all Expressed in all thyroid gland: 53.7 Expressed in all +GSTZ1 GSTZ1-1, MAAI, MAI ENSG00000100577 Glutathione S-transferase zeta 1 14 77320884-77331597 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004701 Approved Approved Nucleus
Cytosol Renal cancer:1.12e-7 (favourable), Ovarian cancer:3.73e-4 (favourable), Breast cancer:4.93e-4 (favourable) Expressed in all Expressed in all liver: 134.5 Expressed in all +KIAA0586 JBTS23, Talpid3 ENSG00000100578 KIAA0586 14 58427385-58551289 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000846, HPA050249 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:7.20e-4 (favourable) Expressed in all Mixed testis: 29.3 Expressed in all +TMED8 FAM15B ENSG00000100580 Transmembrane p24 trafficking protein family member 8 14 77335021-77377109 Predicted intracellular proteins Evidence at protein level HPA001205 Approved Expressed in all Mixed lymph node: 20.8 Expressed in all +SAMD15 C14orf174, FAM15A, FLJ35963 ENSG00000100583 Sterile alpha motif domain containing 15 14 77376689-77391497 Predicted intracellular proteins Evidence at protein level HPA030673, HPA030677 Enhanced Approved Nucleus
Nuclear membrane
Nucleoli Mixed Tissue enhanced testis: 32.0 fallopian tube: 7.3 Mixed +AHSA1 Aha1, C14orf3, hAha1, p38 ENSG00000100591 Activator of HSP90 ATPase activity 1 14 77457870-77469474 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000903, CAB006244 Supported Supported Cytosol Liver cancer:5.04e-6 (unfavourable) Expressed in all Expressed in all fallopian tube: 180.4 Expressed in all +DAAM1 KIAA0666 ENSG00000100592 Dishevelled associated activator of morphogenesis 1 14 59188646-59371405 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026605, HPA064789 Uncertain Approved Plasma membrane
Cytosol Renal cancer:3.77e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 52.1 Expressed in all +ISM2 FLJ32147, TAIL1, THSD3 ENSG00000100593 Isthmin 2 14 77474394-77498850 Predicted secreted proteins Evidence at protein level HPA039314, HPA039742 Supported Supported Nucleoplasm Mixed Tissue enriched 112 placenta: 274.5 epididymis: 2.4 Cell line enriched 21 BEWO: 345.7 +SPTLC2 hLCB2a, KIAA0526, LCB2, LCB2A ENSG00000100596 Serine palmitoyltransferase long chain base subunit 2 14 77505997-77616773 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA027552 Approved Mitochondria Renal cancer:6.69e-8 (favourable), Liver cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all placenta: 29.0 Expressed in all +RIN3 FLJ22439 ENSG00000100599 Ras and Rab interactor 3 14 92513774-92688994 Predicted intracellular proteins Evidence at protein level HPA039836 Uncertain Expressed in all Mixed bone marrow: 29.5 Cell line enhanced HMC-1: 94.1 +LGMN LGMN1, PRSC1 ENSG00000100600 Legumain 14 92703807-92748702 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001426 Enhanced Approved Nucleoplasm
Vesicles Renal cancer:4.70e-4 (favourable) Expressed in all Expressed in all placenta: 360.0 Cell line enhanced RPMI-8226: 587.9;U-266/70: 339.8 +ALKBH1 ABH, alkB, ALKBH, hABH ENSG00000100601 AlkB homolog 1, histone H2A dioxygenase 14 77672404-77708020 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA044087 Approved Renal cancer:1.80e-4 (favourable) Expressed in all Mixed placenta: 5.7 Expressed in all +SNW1 Bx42, NCoA-62, Prp45, PRPF45, SKIIP, SKIP ENSG00000100603 SNW domain containing 1 14 77717599-77761207 Predicted intracellular proteins Evidence at protein level HPA002457, CAB009931, HPA017370 Supported Enhanced Nucleoplasm Liver cancer:1.96e-4 (unfavourable) Expressed in all Expressed in all testis: 85.0 Expressed in all +CHGA ENSG00000100604 Chromogranin A 14 92923080-92935293 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000023, HPA017369, CAB040544, CAB055506, CAB058688 Enhanced Supported Vesicles Breast cancer:7.85e-5 (favourable), Liver cancer:2.40e-4 (unfavourable), Urothelial cancer:3.99e-4 (unfavourable), Pancreatic cancer:4.07e-4 (favourable) Tissue enhanced Tissue enriched 9 parathyroid gland: 7061.6 adrenal gland: 818.1 Group enriched 156 SCLC-21H: 285.4;SH-SY5Y: 700.4 +ITPK1 ENSG00000100605 Inositol-tetrakisphosphate 1-kinase 14 92936914-93116320 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055230 Approved Approved Mitochondria Endometrial cancer:8.56e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 93.1 Expressed in all +DHRS7 retDSR4, SDR34C1 ENSG00000100612 Dehydrogenase/reductase 7 14 60144120-60169856 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031121 Approved Approved Nucleoplasm
Mitochondria Renal cancer:1.92e-10 (favourable), Head and neck cancer:2.51e-4 (unfavourable), Breast cancer:6.42e-4 (favourable), Ovarian cancer:7.99e-4 (unfavourable) Tissue enriched Expressed in all prostate: 650.0 Expressed in all +PPM1A MGC9201, PP2CA, PP2Calpha ENSG00000100614 Protein phosphatase, Mg2+/Mn2+ dependent 1A 14 60245752-60299087 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029209 Approved Supported Plasma membrane
Cytosol Renal cancer:1.57e-9 (favourable) Expressed in all Expressed in all testis: 100.1 Expressed in all +SIX4 AREC3 ENSG00000100625 SIX homeobox 4 14 60709528-60724348 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031794 Uncertain Approved Nucleoplasm Mixed Tissue enriched 5 parathyroid gland: 23.9 skeletal muscle: 4.7 Cell line enhanced A-431: 29.3;RH-30: 31.5 +GALNT16 GalNAc-T16, GALNTL1, KIAA1130 ENSG00000100626 Polypeptide N-acetylgalactosaminyltransferase 16 14 69259277-69357033 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059136 Approved Approved Nucleus Renal cancer:5.23e-6 (favourable) Mixed Mixed cerebral cortex: 28.5 Cell line enhanced AF22: 9.0;hTEC/SVTERT24-B: 17.0;SCLC-21H: 10.5;U-2 OS: 21.2 +ASB2 ASB-2 ENSG00000100628 Ankyrin repeat and SOCS box containing 2 14 93934153-93976791 Predicted intracellular proteins Evidence at protein level Endometrial cancer:3.62e-6 (favourable) Mixed Tissue enhanced skeletal muscle: 85.8 smooth muscle: 25.6 Cell line enhanced Karpas-707: 7.3;RPMI-8226: 6.6;U-266/70: 21.0;U-266/84: 4.6 +CEP128 C14orf145, C14orf61 ENSG00000100629 Centrosomal protein 128 14 80476983-80959517 Predicted intracellular proteins Evidence at protein level HPA000602, HPA001116, HPA018498 Uncertain Supported Microtubule organizing center
Cytosol Mixed Mixed testis: 9.5 Cell line enhanced U-266/70: 83.9 +ERH DROER ENSG00000100632 Enhancer of rudimentary homolog (Drosophila) 14 69380123-69398627 Predicted intracellular proteins Evidence at protein level HPA002567 Approved Approved Nucleoplasm
Cytosol Liver cancer:7.89e-5 (unfavourable) Expressed in all Expressed in all endometrium: 112.0 Expressed in all +HIF1A bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8 ENSG00000100644 Hypoxia inducible factor 1 alpha subunit 14 61695513-61748259 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000907, HPA001275, CAB017442 Supported Supported Nucleoplasm
Nuclear bodies
Plasma membrane Expressed in all Expressed in all bone marrow: 292.4 Mixed +SUSD6 KIAA0247 ENSG00000100647 Sushi domain containing 6 14 69611596-69715142 Predicted membrane proteins Evidence at protein level HPA030464 Uncertain Approved Nucleoplasm
Intermediate filaments Renal cancer:2.16e-4 (favourable) Expressed in all Expressed in all epididymis: 52.4 Expressed in all +SRSF5 HRS, SFRS5, SRP40 ENSG00000100650 Serine and arginine rich splicing factor 5 14 69726900-69772005 Predicted intracellular proteins Evidence at protein level HPA043484, HPA056523 Approved Enhanced Nucleus
Nucleoli Cervical cancer:7.91e-4 (favourable) Expressed in all Expressed in all fallopian tube: 311.9 Expressed in all +SLC10A1 NTCP ENSG00000100652 Solute carrier family 10 member 1 14 69775417-69797289 Predicted membrane proteins, Transporters Evidence at protein level HPA042727 Approved Liver cancer:9.53e-6 (favourable) Tissue enriched Tissue enriched 394 liver: 212.4 gallbladder: 0.5 Not detected +EIF5 ENSG00000100664 Eukaryotic translation initiation factor 5 14 103333544-103345025 Predicted intracellular proteins Evidence at protein level HPA000867, CAB004226 Supported Supported Plasma membrane
Cytosol Renal cancer:5.67e-7 (favourable) Expressed in all Expressed in all testis: 174.0 Expressed in all +SERPINA4 KAL, kallistatin, KLST, KST, PI4 ENSG00000100665 Serpin family A member 4 14 94561091-94569913 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA003607 Approved Endometrial cancer:2.95e-4 (favourable) Group enriched Tissue enhanced gallbladder: 72.6;liver: 242.7 epididymis: 42.8 Group enriched 36 CACO-2: 4.7;Hep G2: 16.4 +SLC8A3 NCX3 ENSG00000100678 Solute carrier family 8 member A3 14 70044217-70189070 Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Group enriched 6 cerebral cortex: 16.3;skeletal muscle: 6.1 adrenal gland: 1.7 Cell line enhanced AF22: 4.3;LHCN-M2: 6.7;SH-SY5Y: 27.3 +DICER1 Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1 ENSG00000100697 Dicer 1, ribonuclease III 14 95086228-95158010 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000694, CAB068185 Approved Supported Cytosol Expressed in all Expressed in all placenta: 32.6 Expressed in all +ZFYVE21 MGC2550, ZF21 ENSG00000100711 Zinc finger FYVE-type containing 21 14 103715730-103733668 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA055721 Uncertain Renal cancer:2.58e-6 (favourable) Expressed in all Expressed in all endometrium: 88.6 Expressed in all +MTHFD1 MTHFC, MTHFD ENSG00000100714 Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 14 64388031-64463457 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000704, HPA001290, HPA015006, HPA050052 Approved Enhanced Cytosol Renal cancer:5.93e-5 (favourable), Pancreatic cancer:6.96e-4 (unfavourable) Expressed in all Expressed in all liver: 198.5 Expressed in all +TCL1A TCL1 ENSG00000100721 T-cell leukemia/lymphoma 1A 14 95709967-95714196 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004045, HPA016604 Enhanced Tissue enriched Tissue enhanced lymph node: 324.7;tonsil: 196.7 spleen: 77.8 Group enriched 147 Daudi: 334.2;REH: 557.7;U-698: 425.7 +ZC3H14 FLJ11806, NY-REN-37, UKp68 ENSG00000100722 Zinc finger CCCH-type containing 14 14 88562909-88627596 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049798, HPA053510 Enhanced Enhanced Nuclear speckles Renal cancer:7.08e-4 (favourable) Expressed in all Expressed in all testis: 327.4 Expressed in all +TELO2 hCLK2, KIAA0683, TEL2 ENSG00000100726 Telomere maintenance 2 16 1493344-1510457 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041348, HPA041473 Approved Supported Nuclear bodies
Cytosol Expressed in all Expressed in all spleen: 15.5 Expressed in all +PCNX1 KIAA0805, KIAA0995, PCNX, PCNXL1, pecanex ENSG00000100731 Pecanex homolog 1 (Drosophila) 14 70907405-71115382 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053532 Approved Nucleoplasm Renal cancer:4.05e-5 (favourable) Expressed in all Expressed in all testis: 38.2 Expressed in all +BDKRB1 B1BKR, BKR1, bradyb1 ENSG00000100739 Bradykinin receptor B1 14 96255824-96268967 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA002935 Approved Mixed Tissue enhanced gallbladder: 18.2 urinary bladder: 9.9 Cell line enhanced BJ hTERT+: 19.8;HHSteC: 20.3;hTEC/SVTERT24-B: 23.1;U-2197: 23.8;U-87 MG: 82.4 +GSKIP C14orf129 ENSG00000100744 GSK3B interacting protein 14 96363452-96387288 Predicted intracellular proteins Evidence at protein level HPA043054, HPA046782 Approved Approved Nucleoli
Golgi apparatus
Vesicles Expressed in all Expressed in all small intestine: 62.0 Expressed in all +VRK1 ENSG00000100749 Vaccinia related kinase 1 14 96797304-96931722 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000660, HPA017929 Enhanced Supported Nucleus
Cytosol Liver cancer:4.15e-4 (unfavourable) Expressed in all Mixed testis: 59.5 Expressed in all +PSMC1 p56, S4 ENSG00000100764 Proteasome 26S subunit, ATPase 1 14 90256495-90275429 Predicted intracellular proteins Evidence at protein level HPA000872 Approved Enhanced Nucleoplasm
Cytosol Head and neck cancer:1.78e-4 (unfavourable) Expressed in all Expressed in all testis: 140.2 Expressed in all +PAPLN MGC50452 ENSG00000100767 Papilin, proteoglycan like sulfated glycoprotein 14 73237497-73274640 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048682, HPA053453 Uncertain Approved Nucleoplasm Expressed in all Mixed spleen: 20.6 Cell line enhanced HHSteC: 12.9;HSkMC: 20.5 +RPS6KA5 MSK1, RLPK ENSG00000100784 Ribosomal protein S6 kinase A5 14 90847862-91060636 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001274, HPA001780, CAB025458 Approved Enhanced Nucleoplasm Mixed Mixed breast: 12.1 Cell line enhanced HMC-1: 40.2 +PPP4R3A FLFL1, FLJ20707, KIAA2010, MSTP033, PP4R3, SMEK1, smk-1, smk1 ENSG00000100796 Protein phosphatase 4 regulatory subunit 3A 14 91457611-91510554 Predicted intracellular proteins Evidence at protein level HPA002568, HPA063917 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 61.2 Expressed in all +C14orf93 FLJ12154 ENSG00000100802 Chromosome 14 open reading frame 93 14 22985908-23010166 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002569 Approved Approved Nucleus
Plasma membrane Breast cancer:5.05e-4 (favourable) Expressed in all Expressed in all skin: 21.7 Expressed in all +PSMB5 MB1, X ENSG00000100804 Proteasome subunit beta 5 14 23016543-23035230 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049518, HPA061796 Approved Supported Nucleus
Centrosome Liver cancer:2.90e-5 (unfavourable), Ovarian cancer:1.08e-4 (favourable), Head and neck cancer:2.85e-4 (unfavourable), Urothelial cancer:4.73e-4 (unfavourable) Expressed in all Expressed in all epididymis: 141.7 Expressed in all +YY1 DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1 ENSG00000100811 YY1 transcription factor 14 100238298-100282792 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001119, CAB009392 Supported Supported Nucleoplasm
Nucleoli fibrillar center
Vesicles Liver cancer:3.44e-4 (unfavourable), Endometrial cancer:6.13e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 65.8 Expressed in all +ACIN1 ACINUS, fSAP152, KIAA0670 ENSG00000100813 Apoptotic chromatin condensation inducer 1 14 23058564-23095614 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA000657 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:4.88e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 77.4 Expressed in all +CCNB1IP1 C14orf18, HEI10 ENSG00000100814 Cyclin B1 interacting protein 1 14 20311368-20333312 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:5.18e-6 (favourable) Expressed in all Expressed in all ovary: 120.9 Expressed in all +TRIP11 CEV14, GMAP-210, GMAP210, Trip230 ENSG00000100815 Thyroid hormone receptor interactor 11 14 91965991-92040896 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002570, HPA070684 Supported Enhanced Nucleus
Golgi apparatus Renal cancer:1.78e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 38.5 Expressed in all +APEX1 APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1 ENSG00000100823 Apurinic/apyrimidinic endodeoxyribonuclease 1 14 20455191-20457772 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000956, HPA002564, CAB004294, CAB047307 Enhanced Enhanced Nucleus Liver cancer:7.82e-5 (unfavourable) Expressed in all Expressed in all ovary: 176.5 Expressed in all +PABPN1 OPMD, PAB2, PABP2 ENSG00000100836 Poly(A) binding protein nuclear 1 14 23321289-23326185 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000637 Supported Approved Renal cancer:2.41e-7 (unfavourable), Liver cancer:3.55e-4 (unfavourable), Pancreatic cancer:9.66e-4 (favourable) Expressed in all Expressed in all testis: 205.2 Expressed in all +EFS CASS3, EFS1, EFS2, HEFS, SIN ENSG00000100842 Embryonal Fyn-associated substrate 14 23356402-23365752 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001581, HPA001790 Approved Uncertain Nucleoplasm
Cytosol Renal cancer:4.09e-5 (unfavourable) Mixed Mixed skin: 59.4 Cell line enhanced AF22: 61.4;BEWO: 50.1;SH-SY5Y: 62.8 +ARHGAP5 GFI2, p190-B, p190BRhoGAP, RhoGAP5 ENSG00000100852 Rho GTPase activating protein 5 14 32076114-32159728 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046993, HPA056507 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:3.97e-8 (favourable) Expressed in all Expressed in all thyroid gland: 114.7 Mixed +CINP MGC849 ENSG00000100865 Cyclin dependent kinase 2 interacting protein 14 102341102-102362916 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all testis: 48.3 Expressed in all +DHRS2 HEP27, SDR25C1 ENSG00000100867 Dehydrogenase/reductase 2 14 23630115-23645639 Predicted intracellular proteins Evidence at protein level HPA053915, HPA069551 Enhanced Enhanced Nucleus
Mitochondria Renal cancer:3.75e-5 (unfavourable), Endometrial cancer:3.23e-4 (unfavourable), Urothelial cancer:6.45e-4 (favourable) Tissue enriched Group enriched 9 breast: 436.3;urinary bladder: 339.0 salivary gland: 40.8 Cell line enhanced Hep G2: 476.9;RT4: 659.6;SK-BR-3: 2967.1;U-2 OS: 1332.4 +SRP54 ENSG00000100883 Signal recognition particle 54 14 34981957-35029567 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA048977, HPA062044 Approved Supported Nucleoli
Cytosol Expressed in all Expressed in all testis: 89.4 Expressed in all +CPNE6 ENSG00000100884 Copine 6 14 24070837-24078100 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031636 Approved Tissue enhanced Group enriched 6 cerebral cortex: 88.0;seminal vesicle: 35.2 kidney: 9.7 Cell line enhanced U-266/84: 1.3 +CHD8 DUPLIN, HELSNF1, KIAA1564 ENSG00000100888 Chromodomain helicase DNA binding protein 8 14 21385194-21456126 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA052186 Supported Nucleoplasm Liver cancer:4.94e-4 (unfavourable), Ovarian cancer:8.35e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 47.1 Expressed in all +PCK2 PEPCK, PEPCK2 ENSG00000100889 Phosphoenolpyruvate carboxykinase 2, mitochondrial 14 24094053-24110598 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB018734, HPA051162, HPA053502 Enhanced Enhanced Mitochondria Liver cancer:2.81e-4 (favourable) Expressed in all Group enriched 6 duodenum: 367.6;kidney: 192.2;liver: 258.6;small intestine: 276.5 colon: 47.0 Expressed in all +KIAA0391 MRPP3, PRORP ENSG00000100890 KIAA0391 14 35121846-35277614 Predicted intracellular proteins Evidence at protein level HPA020459 Approved Supported Nucleus
Mitochondria Mixed Expressed in all parathyroid gland: 42.6 Expressed in all +DCAF11 GL014, PRO2389, WDR23 ENSG00000100897 DDB1 and CUL4 associated factor 11 14 24114195-24125242 Predicted intracellular proteins Evidence at protein level HPA003583, HPA031157 Approved Enhanced Nucleoplasm Renal cancer:3.50e-13 (favourable) Expressed in all Expressed in all parathyroid gland: 74.3 Expressed in all +PSMA6 IOTA, MGC22756, MGC2333, MGC23846, p27K, PROS27 ENSG00000100902 Proteasome subunit alpha 6 14 35278633-35317493 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003049 Approved Supported Nucleoplasm Ovarian cancer:3.27e-4 (favourable) Expressed in all Expressed in all testis: 390.4 Expressed in all +NFKBIA IkappaBalpha, IKBA, MAD-3, NFKBI ENSG00000100906 NFKB inhibitor alpha 14 35401511-35404749 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003815, HPA029207 Approved Enhanced Cytosol Breast cancer:1.33e-5 (favourable) Expressed in all Expressed in all bone marrow: 711.6 Expressed in all +EMC9 C14orf122, CGI-112, FAM158A ENSG00000100908 ER membrane protein complex subunit 9 14 24138959-24141588 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054715 Approved Golgi apparatus Ovarian cancer:2.43e-4 (favourable) Expressed in all Expressed in all adrenal gland: 21.3 Expressed in all +PSME2 PA28beta ENSG00000100911 Proteasome activator subunit 2 14 24143362-24147570 Predicted intracellular proteins Evidence at protein level HPA062661 Approved Nucleus Renal cancer:3.47e-5 (unfavourable), Breast cancer:1.27e-4 (favourable) Expressed in all Expressed in all duodenum: 287.9 Expressed in all +BRMS1L BRMS1, FLJ39177, MGC11296 ENSG00000100916 Breast cancer metastasis-suppressor 1-like 14 35826318-35932325 Predicted intracellular proteins Evidence at protein level HPA046623 Uncertain Supported Nucleoplasm Urothelial cancer:6.87e-6 (unfavourable), Renal cancer:6.55e-5 (favourable), Liver cancer:1.34e-4 (unfavourable), Breast cancer:5.78e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 24.6 Expressed in all +REC8 kleisin-alpha, REC8L1, Rec8p ENSG00000100918 REC8 meiotic recombination protein 14 24171853-24180257 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031727, HPA031729 Approved Approved Nucleoplasm Renal cancer:1.41e-7 (unfavourable), Breast cancer:2.19e-4 (favourable), Pancreatic cancer:5.57e-4 (favourable) Expressed in all Tissue enhanced fallopian tube: 37.4 testis: 28.9 Cell line enhanced AF22: 20.6;MOLT-4: 18.0;SH-SY5Y: 98.0 +TM9SF1 HMP70, MP70 ENSG00000100926 Transmembrane 9 superfamily member 1 14 24189143-24195687 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA059249 Supported Approved Golgi apparatus Lung cancer:2.04e-4 (unfavourable), Cervical cancer:8.94e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 73.0 Expressed in all +SEC23A ENSG00000100934 Sec23 homolog A, coat complex II component 14 39031919-39109646 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043806, HPA069974 Uncertain Approved Nucleoplasm
Vesicles Renal cancer:1.69e-4 (unfavourable), Stomach cancer:2.94e-4 (unfavourable), Colorectal cancer:3.56e-4 (favourable), Cervical cancer:5.75e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 140.0 Expressed in all +GMPR2 ENSG00000100938 Guanosine monophosphate reductase 2 14 24232422-24239242 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000904, HPA067884, HPA068782 Uncertain Approved Nucleoplasm
Nucleoli Renal cancer:2.21e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 144.2 Expressed in all +PNN memA ENSG00000100941 Pinin, desmosome associated protein 14 39175183-39183218 Predicted intracellular proteins, Transporters Evidence at protein level HPA001378 Supported Enhanced Nuclear speckles Prostate cancer:2.44e-4 (unfavourable), Liver cancer:5.79e-4 (unfavourable) Expressed in all Expressed in all epididymis: 143.3 Expressed in all +RABGGTA PTAR3 ENSG00000100949 Rab geranylgeranyltransferase alpha subunit 14 24265538-24271739 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043488 Approved Enhanced Nucleoplasm Thyroid cancer:1.51e-4 (favourable), Renal cancer:5.44e-4 (favourable) Expressed in all Expressed in all esophagus: 34.0 Expressed in all +NFATC4 NFAT3 ENSG00000100968 Nuclear factor of activated T-cells 4 14 24365673-24379604 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031641, CAB032859, HPA076526 Uncertain Supported Nuclear speckles
Cytosol Renal cancer:1.81e-6 (unfavourable), Colorectal cancer:5.84e-4 (unfavourable) Expressed in all Mixed endometrium: 75.9 Cell line enhanced BJ hTERT+: 80.5 +PLTP BPIFE ENSG00000100979 Phospholipid transfer protein 20 45898621-45912155 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB032873 Approved Renal cancer:9.52e-8 (unfavourable) Expressed in all Expressed in all placenta: 635.6 Cell line enhanced HSkMC: 229.0;U-87 MG: 331.6 +PCIF1 bA465L10.1, C20orf67, PPP1R121 ENSG00000100982 PDX1 C-terminal inhibiting factor 1 20 45934628-45948023 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049517 Enhanced Supported Nucleoplasm
Microtubules
Cytokinetic bridge Renal cancer:1.50e-6 (favourable), Endometrial cancer:8.86e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 49.1 Expressed in all +GSS ENSG00000100983 Glutathione synthetase 20 34928430-34955817 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054508, HPA059315 Enhanced Supported Nucleus Renal cancer:7.31e-6 (favourable), Liver cancer:7.21e-5 (unfavourable) Expressed in all Expressed in all epididymis: 105.8 Expressed in all +MMP9 CLG4B ENSG00000100985 Matrix metallopeptidase 9 20 46008908-46016561 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201 Enhanced Approved Cytosol Renal cancer:4.05e-5 (unfavourable), Endometrial cancer:2.55e-4 (favourable), Liver cancer:7.19e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 252.6;lymph node: 117.7 appendix: 82.8 Cell line enriched 8 NB-4: 227.3 +VSX1 PPCD, PPCD1, PPD ENSG00000100987 Visual system homeobox 1 20 25070885-25082365 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Tissue enhanced ovary: 1.7 cerebral cortex: 1.4 Cell line enriched 5 Karpas-707: 3.1 +TRPC4AP C20orf188, dJ756N5.2, DKFZp586C1223, DKFZP727M231, PPP1R158, TRRP4AP ENSG00000100991 Transient receptor potential cation channel subfamily C member 4 associated protein 20 35002404-35092871 Predicted intracellular proteins Evidence at protein level HPA051197, HPA065061 Uncertain Approved Cytosol Liver cancer:6.25e-8 (unfavourable), Renal cancer:1.17e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 72.6 Expressed in all +PYGB ENSG00000100994 Glycogen phosphorylase B 20 25248069-25298014 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031067 Approved Approved Cytosol Lung cancer:1.10e-4 (unfavourable), Urothelial cancer:1.43e-4 (unfavourable), Liver cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 149.4 Expressed in all +ABHD12 ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106 ENSG00000100997 Abhydrolase domain containing 12 20 25294743-25390983 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026866 Uncertain Cervical cancer:1.30e-5 (favourable), Breast cancer:3.81e-5 (unfavourable), Liver cancer:7.18e-4 (unfavourable) Expressed in all Expressed in all epididymis: 137.3 Expressed in all +PROCR CCD41, CD201, EPCR ENSG00000101000 Protein C receptor 20 35172073-35216240 Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039461 Enhanced Renal cancer:7.62e-6 (unfavourable) Expressed in all Expressed in all adipose tissue: 63.0 Cell line enhanced HMC-1: 339.1;HUVEC TERT2: 510.3;TIME: 297.7 +GINS1 KIAA0186, PSF1 ENSG00000101003 GINS complex subunit 1 20 25407727-25452628 Predicted intracellular proteins Evidence at protein level HPA051185 Uncertain Approved Nucleoplasm Renal cancer:5.42e-11 (unfavourable), Liver cancer:4.61e-7 (unfavourable), Pancreatic cancer:5.62e-4 (unfavourable) Expressed in all Tissue enhanced testis: 14.7 lymph node: 6.5 Mixed +NINL KIAA0980, NLP ENSG00000101004 Ninein like 20 25452705-25585517 Predicted intracellular proteins Evidence at protein level HPA000686 Uncertain Approved Cytokinetic bridge
Cytosol Renal cancer:1.03e-5 (favourable), Pancreatic cancer:1.47e-4 (favourable) Expressed in all Mixed parathyroid gland: 17.9 Cell line enhanced Hep G2: 25.6;SCLC-21H: 26.8 +CD40 Bp50, p50, TNFRSF5 ENSG00000101017 CD40 molecule 20 46118272-46129863 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002495, HPA031567, HPA031568, CAB072868 Enhanced Renal cancer:4.48e-4 (unfavourable) Expressed in all Expressed in all lymph node: 64.7 Cell line enhanced CAPAN-2: 63.4;EFO-21: 116.6 +UQCC1 BFZB, C20orf44, CBP3, FLJ10850, UQCC ENSG00000101019 Ubiquinol-cytochrome c reductase complex assembly factor 1 20 35302566-35412141 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034875 Approved Approved Nucleoplasm
Plasma membrane
Actin filaments Expressed in all Expressed in all parathyroid gland: 43.4 Expressed in all +ZMYND8 PRKCBP1, RACK7 ENSG00000101040 Zinc finger MYND-type containing 8 20 47209214-47356889 Predicted intracellular proteins Evidence at protein level HPA020949 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:7.06e-5 (unfavourable), Breast cancer:2.56e-4 (unfavourable), Liver cancer:2.62e-4 (unfavourable) Expressed in all Expressed in all epididymis: 40.5 Expressed in all +SGK2 ENSG00000101049 SGK2, serine/threonine kinase 2 20 43558968-43588237 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008859, HPA011387 Uncertain Supported Nucleoplasm Urothelial cancer:5.65e-4 (favourable) Group enriched Mixed kidney: 43.2 Group enriched 5 A549: 16.2;CAPAN-2: 12.2;EFO-21: 6.5;Hep G2: 12.5;RPTEC TERT1: 19.0 +IFT52 C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5 ENSG00000101052 Intraflagellar transport 52 20 43590931-43647296 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA063367, HPA067423 Enhanced Approved Cytosol Liver cancer:3.30e-6 (unfavourable), Testis cancer:3.33e-4 (favourable) Expressed in all Expressed in all fallopian tube: 61.3 Expressed in all +MYBL2 B-MYB, BMYB ENSG00000101057 MYB proto-oncogene like 2 20 43667019-43716496 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017114, HPA030530, HPA055416 Uncertain Enhanced Nucleoplasm
Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:2.11e-7 (unfavourable), Endometrial cancer:9.73e-4 (unfavourable) Tissue enriched Tissue enhanced bone marrow: 57.0;lymph node: 67.3;tonsil: 49.9 appendix: 32.7 Mixed +R3HDML dJ881L22.3 ENSG00000101074 R3H domain containing like 20 44336986-44351235 Predicted secreted proteins Evidence at protein level HPA070264 Enhanced Tissue enhanced Tissue enhanced duodenum: 2.2;small intestine: 2.7 testis: 0.8 Not detected +HNF4A HNF4, MODY, MODY1, NR2A1, TCF14 ENSG00000101076 Hepatocyte nuclear factor 4 alpha 20 44355700-44434596 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004712, CAB019417 Enhanced Supported Nucleoplasm Tissue enhanced Group enriched 6 colon: 58.0;duodenum: 103.0;kidney: 44.7;liver: 51.0;rectum: 47.8;small intestine: 90.9;stomach: 21.9 gallbladder: 9.2 Group enriched 8 CACO-2: 126.0;Hep G2: 77.0 +NDRG3 ENSG00000101079 NDRG family member 3 20 36651766-36746078 Predicted intracellular proteins Evidence at protein level HPA017851, HPA018256 Approved Liver cancer:4.35e-4 (unfavourable) Expressed in all Expressed in all testis: 125.3 Expressed in all +SLA2 C20orf156, FLJ21992, SLAP-2 ENSG00000101082 Src like adaptor 2 20 36612318-36646216 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053746, HPA058217 Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:6.77e-8 (unfavourable), Cervical cancer:7.36e-4 (favourable) Mixed Tissue enhanced lymph node: 11.8 spleen: 8.9 Cell line enriched 9 HEL: 81.2 +C20orf24 PNAS-11, RIP5 ENSG00000101084 Chromosome 20 open reading frame 24 20 36605734-36612557 Predicted membrane proteins Evidence at protein level HPA057387 Uncertain Approved Cytosol Liver cancer:4.56e-6 (unfavourable), Renal cancer:2.46e-4 (unfavourable) Expressed in all Expressed in all esophagus: 83.2 Expressed in all +NFATC2 NF-ATP, NFAT1, NFATp ENSG00000101096 Nuclear factor of activated T-cells 2 20 51386957-51562831 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008789, CAB018567, HPA024369 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:1.57e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 26.8 Cell line enhanced HDLM-2: 22.7;HMC-1: 23.5;WM-115: 40.4 +RIMS4 C20orf190, dJ781B1.3 ENSG00000101098 Regulating synaptic membrane exocytosis 4 20 44751808-44810338 Predicted intracellular proteins Evidence at protein level HPA060928 Approved Approved Nucleoplasm Group enriched Tissue enhanced cerebral cortex: 27.3;testis: 20.3 fallopian tube: 13.3 Cell line enhanced HAP1: 20.7;SCLC-21H: 48.2;SH-SY5Y: 22.3;SiHa: 15.5 +PABPC1L C20orf119, dJ1069P2.3, ePAB, PABPC1L1 ENSG00000101104 Poly(A) binding protein cytoplasmic 1 like 20 44910062-44959035 Predicted intracellular proteins Evidence at protein level HPA066650 Approved Nuclear bodies
Cytosol Renal cancer:4.00e-15 (unfavourable), Colorectal cancer:3.80e-4 (unfavourable), Urothelial cancer:8.84e-4 (favourable) Expressed in all Mixed thyroid gland: 54.1 Expressed in all +STK4 KRS2, MST1, YSK3 ENSG00000101109 Serine/threonine kinase 4 20 44966474-45079959 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004038, HPA015270 Approved Enhanced Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:1.84e-5 (unfavourable), Liver cancer:8.04e-4 (unfavourable) Expressed in all Expressed in all lymph node: 50.6 Expressed in all +SALL4 dJ1112F19.1, ZNF797 ENSG00000101115 Spalt like transcription factor 4 20 51782331-51802520 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015291, HPA015791 Enhanced Enhanced Nucleoplasm Tissue enriched Group enriched 7 parathyroid gland: 6.7;prostate: 1.4;testis: 5.8;thyroid gland: 3.5 urinary bladder: 0.6 Cell line enhanced AF22: 24.7;AN3-CA: 16.2;BEWO: 32.0;NTERA-2: 60.1;SiHa: 16.5 +ADNP ADNP1, KIAA0784 ENSG00000101126 Activity dependent neuroprotector homeobox 20 50888919-50931240 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006371 Supported Approved Nucleoplasm Liver cancer:1.65e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 81.7 Expressed in all +PFDN4 C-1, C1, PFD4 ENSG00000101132 Prefoldin subunit 4 20 54207847-54228052 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024055 Approved Renal cancer:1.47e-10 (unfavourable), Liver cancer:7.66e-5 (unfavourable), Head and neck cancer:9.40e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 11.3 Expressed in all +DOK5 C20orf180, dJ805C22.1 ENSG00000101134 Docking protein 5 20 54475597-54651171 Predicted intracellular proteins Evidence at protein level HPA054460, HPA065235 Uncertain Approved Focal adhesion sites Endometrial cancer:8.99e-7 (unfavourable) Group enriched Tissue enhanced cerebral cortex: 22.0;fallopian tube: 20.0 skeletal muscle: 15.7 Cell line enhanced AF22: 32.4;hTEC/SVTERT24-B: 13.7;U-138 MG: 50.6 +CSTF1 ENSG00000101138 Cleavage stimulation factor subunit 1 20 56392371-56406369 Predicted intracellular proteins Evidence at protein level CAB019270, HPA047275, HPA065000 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all testis: 31.3 Expressed in all +BMP7 OP-1 ENSG00000101144 Bone morphogenetic protein 7 20 57168748-57266629 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA057757 Approved Nucleus
Nucleoli
Vesicles Endometrial cancer:2.91e-4 (unfavourable) Mixed Tissue enhanced thyroid gland: 76.7 placenta: 36.8 Cell line enhanced Daudi: 124.6;MCF7: 154.9;SK-BR-3: 95.4;U-698: 163.1 +RAE1 Mnrp41 ENSG00000101146 Ribonucleic acid export 1 20 57351010-57379211 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA048795 Supported Nucleus
Nucleoli fibrillar center Liver cancer:2.12e-7 (unfavourable), Endometrial cancer:2.44e-4 (unfavourable) Expressed in all Tissue enriched 6 testis: 183.9 bone marrow: 31.4 Expressed in all +TPD52L2 D54, hD54 ENSG00000101150 Tumor protein D52 like 2 20 63865228-63891545 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047489 Approved Approved Vesicles
Cytosol Renal cancer:1.74e-8 (unfavourable), Liver cancer:1.39e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 105.2 Expressed in all +DNAJC5 CLN4, DNAJC5A, FLJ00118, FLJ13070 ENSG00000101152 DnaJ heat shock protein family (Hsp40) member C5 20 63895182-63936031 Disease related genes, Predicted membrane proteins Evidence at protein level HPA012737, HPA013154 Approved Uncertain Golgi apparatus Renal cancer:7.70e-6 (favourable), Liver cancer:8.82e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 73.6 Expressed in all +NELFCD HSPC130, NELF-C, NELF-D, TH1, TH1L ENSG00000101158 Negative elongation factor complex member C/D 20 58981208-58995133 Predicted intracellular proteins Evidence at protein level HPA050641, HPA066262 Supported Nucleoplasm
Nuclear bodies
Vesicles
Cytosol Endometrial cancer:4.98e-5 (unfavourable), Liver cancer:1.90e-4 (unfavourable), Prostate cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 52.6 Expressed in all +CTSZ CTSX ENSG00000101160 Cathepsin Z 20 58995185-59007247 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB025114, HPA049876, HPA053504 Supported Supported Vesicles Renal cancer:5.72e-5 (unfavourable) Expressed in all Expressed in all lung: 476.8 Cell line enhanced fHDF/TERT166: 693.2 +PRPF6 ANT-1, bB152O15.1, C20orf14, hPrp6, Prp6, RP60, SNRNP102, TOM, U5-102K ENSG00000101161 Pre-mRNA processing factor 6 20 63981135-64033100 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047106 Enhanced Enhanced Nuclear speckles Expressed in all Expressed in all fallopian tube: 80.3 Expressed in all +TUBB1 dJ543J19.4 ENSG00000101162 Tubulin beta 1 class VI 20 59019254-59026654 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004286, HPA043640, HPA046280 Approved Not detected Group enriched 5 bone marrow: 4.8;lung: 2.1;placenta: 1.5;spleen: 5.6;testis: 1.5 gallbladder: 0.5 Cell line enriched 20 HEL: 24.9 +PRELID3B C20orf45, dJ543J19.5, SLMO2 ENSG00000101166 PRELI domain containing 3B 20 59033145-59042909 Predicted intracellular proteins Evidence at protein level HPA047721 Uncertain Approved Nucleus Liver cancer:6.96e-5 (unfavourable), Endometrial cancer:5.04e-4 (unfavourable) Expressed in all Expressed in all duodenum: 88.0 Expressed in all +HRH3 GPCR97 ENSG00000101180 Histamine receptor H3 20 62214970-62220267 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Tissue enriched 17 cerebral cortex: 11.1 adrenal gland: 0.6 Cell line enriched 7 SCLC-21H: 18.6 +MTG2 dJ1005F21.2, FLJ10741, GTPBP5, ObgH1 ENSG00000101181 Mitochondrial ribosome associated GTPase 2 20 62183029-62203568 Predicted intracellular proteins Evidence at protein level HPA047379 Approved Pancreatic cancer:6.31e-5 (favourable) Expressed in all Expressed in all adrenal gland: 15.8 Expressed in all +PSMA7 C6, HSPC, RC6-1, XAPC7 ENSG00000101182 Proteasome subunit alpha 7 20 62136735-62143440 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB046007, CAB046008, HPA047266 Enhanced Liver cancer:2.54e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 208.4 Expressed in all +SLCO4A1 OATP-E, OATP4A1, SLC21A12 ENSG00000101187 Solute carrier organic anion transporter family member 4A1 20 62642445-62685785 Predicted membrane proteins, Transporters Evidence at protein level HPA030669, HPA030670 Uncertain Supported Cell Junctions Lung cancer:4.74e-4 (unfavourable) Expressed in all Mixed esophagus: 10.5 Cell line enhanced PC-3: 178.2;RPTEC TERT1: 137.9 +NTSR1 NTR ENSG00000101188 Neurotensin receptor 1 20 62708837-62762771 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA050299 Supported Plasma membrane Tissue enhanced Not detected cerebral cortex: 0.5 Cell line enriched 6 PC-3: 53.5 +MRGBP C20orf20, Eaf7, FLJ10914, MRG15BP ENSG00000101189 MRG domain binding protein 20 62796453-62801738 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017012 Enhanced Supported Nucleus Renal cancer:2.48e-6 (unfavourable), Liver cancer:3.80e-6 (unfavourable), Endometrial cancer:2.33e-4 (unfavourable) Expressed in all Tissue enriched 6 testis: 64.3 ovary: 10.6 Expressed in all +TCFL5 bHLHe82, CHA, E2BP-1, Figlb ENSG00000101190 Transcription factor like 5 20 62841115-62861763 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055223 Approved Supported Nucleoplasm Endometrial cancer:3.24e-4 (unfavourable) Expressed in all Expressed in all testis: 144.4 Expressed in all +DIDO1 BYE1, C20orf158, DATF1, DIO-1, DIO1, dJ885L7.8, FLJ11265, KIAA0333 ENSG00000101191 Death inducer-obliterator 1 20 62877738-62937952 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004374, HPA049904 Supported Approved Nucleoplasm
Vesicles
Cytosol Pancreatic cancer:3.88e-4 (favourable), Head and neck cancer:5.13e-4 (favourable) Expressed in all Expressed in all fallopian tube: 48.2 Expressed in all +GID8 bA305P22.1, C20orf11, FLJ20602, TWA1 ENSG00000101193 GID complex subunit 8 homolog 20 62938119-62948475 Predicted intracellular proteins Evidence at protein level HPA049929, HPA055047 Approved Supported Nucleoplasm
Cell Junctions Renal cancer:3.22e-4 (favourable), Endometrial cancer:4.78e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 32.5 Expressed in all +SLC17A9 C20orf59, FLJ23412, VNUT ENSG00000101194 Solute carrier family 17 member 9 20 62952647-62969585 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA047470, HPA056499 Uncertain Approved Nucleoplasm Renal cancer:2.78e-15 (unfavourable) Mixed Mixed stomach: 8.6 Cell line enhanced Hep G2: 46.7;U-937: 33.7 +BIRC7 KIAP, ML-IAP, mliap, RNF50 ENSG00000101197 Baculoviral IAP repeat containing 7 20 63235883-63240507 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047850 Supported Nucleus
Microtubule organizing center
Cytosol Tissue enriched Tissue enhanced placenta: 9.2 skin: 2.7 Cell line enhanced REH: 32.5;SK-MEL-30: 145.1;U-937: 33.0 +NKAIN4 bA261N11.2, C20orf58, FAM77A ENSG00000101198 Sodium/potassium transporting ATPase interacting 4 20 63240784-63272694 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA029876 Approved Endometrial cancer:3.14e-4 (unfavourable) Tissue enriched Tissue enriched 13 cerebral cortex: 71.8 kidney: 5.5 Cell line enhanced BEWO: 23.2;MOLT-4: 33.2 +ARFGAP1 ARF1GAP, bA261N11.3, FLJ10767 ENSG00000101199 ADP ribosylation factor GTPase activating protein 1 20 63272785-63289793 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051019, HPA056273 Approved Supported Nuclear membrane
Golgi apparatus
Vesicles Renal cancer:3.48e-7 (unfavourable), Pancreatic cancer:4.57e-4 (favourable) Expressed in all Expressed in all testis: 32.2 Expressed in all +AVP ADH, ARVP ENSG00000101200 Arginine vasopressin 20 3082556-3084724 Disease related genes, Predicted secreted proteins Evidence at protein level CAB025318, HPA071892 Supported Supported Not detected Not detected bone marrow,testis: 0.5 Cell line enriched 9 NB-4: 1.4 +COL20A1 KIAA1510 ENSG00000101203 Collagen type XX alpha 1 chain 20 63293186-63334851 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051962 Uncertain Tissue enriched Tissue enriched 7 cerebral cortex: 16.2 testis: 2.3 Not detected +CHRNA4 BFNC, EBN, EBN1 ENSG00000101204 Cholinergic receptor nicotinic alpha 4 subunit 20 63343223-63378401 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB034064 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 6.9;parathyroid gland: 17.4 liver: 3.9 Cell line enhanced U-2 OS: 2.6 +EEF1A2 EEF1AL, HS1, STN, STNL ENSG00000101210 Eukaryotic translation elongation factor 1 alpha 2 20 63488013-63499315 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034019, HPA051759, HPA053862, HPA056990 Approved Enhanced Nucleoli
Cytosol Endometrial cancer:2.90e-5 (unfavourable), Head and neck cancer:9.11e-4 (unfavourable) Expressed in all Group enriched 6 cerebral cortex: 409.3;heart muscle: 425.6;skeletal muscle: 1372.7 adrenal gland: 127.7 Cell line enhanced MCF7: 899.8;SCLC-21H: 694.7;T-47d: 410.5;U-2 OS: 431.5 +PTK6 BRK ENSG00000101213 Protein tyrosine kinase 6 20 63528001-63537370 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB032952, HPA036070, HPA036071 Approved Supported Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Renal cancer:1.26e-9 (unfavourable), Pancreatic cancer:1.96e-4 (unfavourable) Mixed Tissue enhanced esophagus: 61.0;skin: 60.4 duodenum: 29.2 Cell line enhanced A-431: 19.4;CAPAN-2: 36.5;HaCaT: 30.0;hTCEpi: 32.5;RT4: 21.3;T-47d: 23.7 +GMEB2 KIAA1269, P79PIF, PIF79 ENSG00000101216 Glucocorticoid modulatory element binding protein 2 20 63587602-63627041 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009706, HPA067455 Approved Enhanced Nucleoplasm Expressed in all Expressed in all testis: 12.8 Expressed in all +C20orf27 FLJ20550 ENSG00000101220 Chromosome 20 open reading frame 27 20 3753508-3768387 Predicted intracellular proteins Evidence at protein level HPA047483 Approved Approved Nucleoplasm
Cytosol Renal cancer:6.18e-6 (unfavourable), Liver cancer:1.69e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 56.5 Expressed in all +SPEF1 C20orf28, CLAMP, DKFZP434I114, SPEF1A ENSG00000101222 Sperm flagellar 1 20 3777504-3781448 Predicted intracellular proteins Evidence at protein level HPA050786 Enhanced Thyroid cancer:9.87e-4 (unfavourable) Mixed Tissue enhanced fallopian tube: 15.9;testis: 6.5 cerebral cortex: 2.9 Cell line enhanced A549: 1.9;MCF7: 1.2 +CDC25B ENSG00000101224 Cell division cycle 25B 20 3786772-3806121 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038892, HPA038893, HPA075215 Enhanced Supported Vesicles
Mitotic spindle Renal cancer:2.94e-13 (unfavourable), Liver cancer:1.19e-4 (unfavourable), Endometrial cancer:4.76e-4 (unfavourable) Expressed in all Mixed lymph node: 56.6 Expressed in all +ISM1 bA149I18.1, C20orf82 ENSG00000101230 Isthmin 1 20 13221771-13300651 Predicted secreted proteins Evidence at protein level Renal cancer:9.32e-6 (unfavourable) Expressed in all Tissue enhanced thyroid gland: 74.7 placenta: 24.8 Cell line enhanced ASC diff: 40.6;Hep G2: 16.4 +RNF24 G1L ENSG00000101236 Ring finger protein 24 20 3927309-4015582 Predicted membrane proteins Evidence at protein level HPA011900 Approved Supported Golgi apparatus Renal cancer:2.67e-7 (unfavourable), Liver cancer:3.81e-5 (unfavourable) Expressed in all Mixed bone marrow: 34.2 Expressed in all +ARFRP1 ARL18, ARP, Arp1 ENSG00000101246 ADP ribosylation factor related protein 1 20 63698642-63708025 Predicted intracellular proteins Evidence at protein level HPA047028, HPA050634 Approved Supported Golgi apparatus Expressed in all Expressed in all spleen: 27.9 Expressed in all +NDUFAF5 C20orf7, dJ842G6.1 ENSG00000101247 NADH:ubiquinone oxidoreductase complex assembly factor 5 20 13784950-13821582 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051184 Uncertain Renal cancer:2.27e-6 (favourable) Expressed in all Mixed skeletal muscle: 6.9 Expressed in all +SEL1L2 C20orf50, DKFZp434C1826 ENSG00000101251 SEL1L2 ERAD E3 ligase adaptor subunit 20 13849247-13996443 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA059121 Approved Not detected Tissue enriched 63 testis: 12.6 endometrium: 0.2 Not detected +TRIB3 C20orf97, dJ1103G7.3, TRB3 ENSG00000101255 Tribbles pseudokinase 3 20 362835-397559 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055442 Approved Supported Nucleus
Nuclear membrane
Nucleoli Renal cancer:2.07e-13 (unfavourable), Liver cancer:6.75e-5 (unfavourable), Head and neck cancer:1.70e-4 (unfavourable) Expressed in all Tissue enhanced thyroid gland: 51.4 liver: 12.5 Cell line enhanced HHSteC: 437.1;hTERT-HME1: 292.4;SK-MEL-30: 388.6 +RASSF2 CENP-34, KIAA0168 ENSG00000101265 Ras association domain family member 2 20 4780023-4823645 Predicted intracellular proteins Evidence at protein level HPA051200 Uncertain Supported Nucleoplasm
Golgi apparatus
Plasma membrane
Cytosol Renal cancer:7.82e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 148.5 lymph node: 68.8 Cell line enhanced HL-60: 59.0;NB-4: 60.4;U-937: 91.0 +CSNK2A1 ENSG00000101266 Casein kinase 2 alpha 1 20 473591-543821 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB020680, HPA059206, HPA061698, CAB069395 Enhanced Supported Nucleoplasm Liver cancer:4.11e-6 (unfavourable) Expressed in all Expressed in all testis: 129.5 Expressed in all +SLC52A3 bA371L19.1, C20orf54, hRFT2, RFVT3 ENSG00000101276 Solute carrier family 52 member 3 20 760080-776015 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA049391, HPA059078 Approved Stomach cancer:5.51e-6 (favourable) Expressed in all Tissue enhanced testis: 62.3 small intestine: 18.1 Cell line enhanced CAPAN-2: 33.7;SK-BR-3: 10.4;T-47d: 16.0 +ANGPT4 ENSG00000101280 Angiopoietin 4 20 869899-916317 Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB013260, CAB013305 Uncertain Not detected Tissue enhanced cervix, uterine: 5.4 adipose tissue: 2.7 Group enriched 92 ASC diff: 23.2;BEWO: 47.4 +RSPO4 C20orf182, dJ824F16.3 ENSG00000101282 R-spondin 4 20 958452-1002264 Disease related genes, Predicted secreted proteins Evidence at protein level HPA048887 Uncertain Endometrial cancer:2.98e-6 (unfavourable) Mixed Tissue enhanced lung: 6.8 testis: 2.4 Cell line enhanced BEWO: 3.0;NTERA-2: 6.4;SK-BR-3: 3.3;U-2 OS: 7.7 +CDS2 ENSG00000101290 CDP-diacylglycerol synthase 2 20 5126786-5197887 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA019698 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:3.53e-9 (favourable) Expressed in all Expressed in all cerebral cortex: 48.9 Expressed in all +PROKR2 dJ680N4.3, GPR73b, GPR73L1, GPRg2, KAL3, PKR2 ENSG00000101292 Prokineticin receptor 2 20 5302040-5314369 Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA047281 Uncertain Not detected Tissue enhanced cerebral cortex: 3.0 bone marrow: 0.8 Cell line enhanced NTERA-2: 1.1;SH-SY5Y: 2.2 +HM13 dJ324O17.1, H13, IMP1, IMPAS, PSENL3, PSL3, SPP, SPPL1 ENSG00000101294 Histocompatibility minor 13 20 31514428-31577923 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA045089, HPA056062 Approved Supported Endoplasmic reticulum Renal cancer:4.64e-12 (unfavourable), Liver cancer:1.95e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 154.2 Expressed in all +SNPH bA314N13.5 ENSG00000101298 Syntaphilin 20 1266316-1309328 Predicted membrane proteins Evidence at protein level HPA049393 Approved Uncertain Cytokinetic bridge
Mitochondria Pancreatic cancer:6.97e-5 (favourable) Mixed Tissue enhanced cerebral cortex: 33.6 seminal vesicle: 15.6 Mixed +MYLK2 KMLC, MLCK2, skMLCK ENSG00000101306 Myosin light chain kinase 2 20 31819308-31834689 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA059704, HPA059890 Enhanced Supported Endoplasmic reticulum Glioma:5.74e-4 (favourable) Tissue enhanced Tissue enriched 49 skeletal muscle: 253.1 esophagus: 5.1 Cell line enhanced RH-30: 10.2;RPMI-8226: 6.2 +SIRPB1 CD172b, SIRP-BETA-1 ENSG00000101307 Signal regulatory protein beta 1 20 1563521-1620061 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA047463 Uncertain Uncertain Vesicles Mixed Tissue enhanced appendix: 38.7;bone marrow: 33.7 lung: 28.0 Cell line enhanced HMC-1: 46.6;NB-4: 46.7;THP-1: 38.2 +SEC23B CDA-II, CDAII, CDAN2, HEMPAS ENSG00000101310 Sec23 homolog B, coat complex II component 20 18507493-18561415 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008216, HPA069974 Uncertain Supported Vesicles Endometrial cancer:8.25e-4 (favourable) Expressed in all Expressed in all thyroid gland: 85.7 Expressed in all +FERMT1 C20orf42, FLJ20116, KIND1, UNC112A, URP1 ENSG00000101311 Fermitin family member 1 20 6074845-6123544 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039778, HPA041966 Approved Pancreatic cancer:6.60e-4 (unfavourable) Expressed in all Mixed rectum: 30.8 Cell line enhanced CAPAN-2: 58.4;HaCaT: 68.4;HBEC3-KT: 56.3 +HAO1 GOX, GOX1 ENSG00000101323 Hydroxyacid oxidase 1 20 7882981-7940474 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049552 Enhanced Tissue enriched Tissue enriched 305 liver: 308.6 kidney: 1.0 Not detected +PDYN ADCA, PENKB, SCA23 ENSG00000101327 Prodynorphin 20 1978757-1994285 Disease related genes, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level HPA049841, HPA053342 Approved Supported Group enriched Tissue enriched 11 cerebral cortex: 63.3 testis: 5.5 Not detected +CCM2L C20orf160, dJ310O13.5 ENSG00000101331 CCM2 like scaffolding protein 20 32010450-32032180 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008434, HPA071063 Uncertain Approved Nucleoplasm Expressed in all Tissue enriched 8 spleen: 122.6 placenta: 15.0 Cell line enhanced EFO-21: 9.4;HUVEC TERT2: 10.0;NTERA-2: 6.4;SCLC-21H: 12.8 +PLCB4 ENSG00000101333 Phospholipase C beta 4 20 9068763-9481242 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007951 Supported Approved Nucleoplasm
Microtubules Endometrial cancer:2.11e-4 (favourable) Tissue enhanced Tissue enhanced thyroid gland: 58.5 epididymis: 30.5 Cell line enhanced fHDF/TERT166: 87.3;LHCN-M2: 74.5;RPTEC TERT1: 85.5 +MYL9 LC20, MLC2, MRLC1, MYRL2 ENSG00000101335 Myosin light chain 9 20 36541484-36551447 Predicted intracellular proteins Evidence at protein level HPA039262, HPA045244, HPA059197 Supported Approved Nucleus
Nucleoli fibrillar center Renal cancer:7.92e-7 (unfavourable) Expressed in all Expressed in all seminal vesicle: 3139.3 Cell line enhanced BJ: 876.7;fHDF/TERT166: 644.0 +HCK JTK9 ENSG00000101336 HCK proto-oncogene, Src family tyrosine kinase 20 32052188-32101856 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005195, HPA063768 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:1.66e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 149.6;spleen: 113.2 lung: 74.1 Group enriched 8 THP-1: 48.4;U-937: 161.1 +TM9SF4 dJ836N17.2, KIAA0255 ENSG00000101337 Transmembrane 9 superfamily member 4 20 32109506-32167258 Predicted membrane proteins, Transporters Evidence at protein level HPA064099 Approved Approved Mitochondria Endometrial cancer:6.37e-6 (unfavourable), Liver cancer:2.15e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 93.1 Expressed in all +TLDC2 C20orf118, dJ132F21.2 ENSG00000101342 TBC/LysM-associated domain containing 2 20 36876121-36894235 Predicted intracellular proteins Evidence at transcript level HPA047468 Approved Renal cancer:9.97e-5 (unfavourable) Tissue enhanced Tissue enhanced duodenum: 19.0;small intestine: 20.1 rectum: 13.3 Cell line enriched 10 HMC-1: 30.5 +CRNKL1 CLF, Clf1, CRN, SYF3 ENSG00000101343 Crooked neck pre-mRNA splicing factor 1 20 20034368-20056046 Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:8.06e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.1 Expressed in all +POFUT1 FUT12, KIAA0180, O-Fuc-T, O-FUT ENSG00000101346 Protein O-fucosyltransferase 1 20 32207880-32238667 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA054519, HPA059935 Approved Approved Centrosome Expressed in all Expressed in all parathyroid gland: 35.7 Expressed in all +SAMHD1 AGS5, HDDC1, Mg11, MOP-5, SBBI88 ENSG00000101347 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 20 36890229-36951843 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047072 Enhanced Supported Nucleoplasm
Plasma membrane Renal cancer:5.12e-4 (unfavourable) Expressed in all Expressed in all spleen: 133.3 Cell line enhanced ASC diff: 345.7;BJ hTERT+ SV40 Large T+: 170.4;BJ hTERT+ SV40 Large T+ RasG12V: 204.5 +PAK5 KIAA1264, PAK7 ENSG00000101349 P21 (RAC1) activated kinase 5 20 9537389-9839041 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA020444 Approved Approved Nucleoplasm Mixed Tissue enriched 5 cerebral cortex: 13.4 adrenal gland: 2.6 Group enriched 10 SCLC-21H: 5.6;SH-SY5Y: 1.8 +KIF3B FLA8, KIAA0359, KLP-11 ENSG00000101350 Kinesin family member 3B 20 32277664-32335011 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007119 Approved Uncertain Nucleoplasm
Nucleoli
Golgi apparatus Renal cancer:1.44e-12 (favourable) Expressed in all Expressed in all parathyroid gland: 80.8 Expressed in all +MROH8 C20orf131, C20orf132, dJ621N11.3, dJ621N11.4 ENSG00000101353 Maestro heat like repeat family member 8 20 37101226-37179588 Predicted intracellular proteins Evidence at transcript level HPA060298 Uncertain Approved Nucleus Mixed Tissue enhanced testis: 41.1 epididymis: 8.8 Mixed +NOP56 NOL5A, SCA36 ENSG00000101361 NOP56 ribonucleoprotein 20 2652145-2658393 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049918, CAB075757 Enhanced Enhanced Nucleoli fibrillar center Renal cancer:2.22e-16 (unfavourable), Liver cancer:1.59e-7 (unfavourable), Endometrial cancer:1.24e-4 (unfavourable), Melanoma:6.77e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 60.3 Expressed in all +MANBAL dJ1141E15.2 ENSG00000101363 Mannosidase beta like 20 37289638-37317260 Predicted membrane proteins Evidence at protein level HPA052348 Uncertain Approved Nucleus
Mitochondria Renal cancer:3.62e-4 (favourable), Liver cancer:7.07e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 96.2 Expressed in all +IDH3B RP46 ENSG00000101365 Isocitrate dehydrogenase 3 (NAD(+)) beta 20 2658395-2664219 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA049387, HPA054180 Enhanced Enhanced Mitochondria Renal cancer:6.78e-8 (favourable), Liver cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 100.5 Expressed in all +MAPRE1 EB1 ENSG00000101367 Microtubule associated protein RP/EB family member 1 20 32819893-32850405 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003600, CAB009337, CAB019391 Enhanced Enhanced Microtubule organizing center
Cytosol Liver cancer:6.33e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 128.4 Expressed in all +JAG1 AGS, AHD, AWS, CD339, HJ1, JAGL1 ENSG00000101384 Jagged 1 20 10637684-10674107 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB010343, HPA021555 Enhanced Supported Golgi apparatus
Plasma membrane Pancreatic cancer:4.10e-6 (unfavourable) Expressed in all Expressed in all placenta: 97.1 Cell line enhanced HBEC3-KT: 150.8;hTERT-HME1: 96.7;U-251 MG: 151.3 +CDK5RAP1 C20orf34, C42, CGI-05, HSPC167 ENSG00000101391 CDK5 regulatory subunit associated protein 1 20 33358839-33401561 Predicted intracellular proteins Evidence at protein level HPA066301 Approved Nuclear speckles
Mitochondria Prostate cancer:8.07e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 19.4 Expressed in all +SNTA1 LQT12, SNT1, TACIP1 ENSG00000101400 Syntrophin alpha 1 20 33407955-33443892 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB037059 Approved Endometrial cancer:9.60e-6 (unfavourable), Pancreatic cancer:3.72e-4 (favourable), Melanoma:7.08e-4 (favourable) Expressed in all Expressed in all thyroid gland: 102.0 Mixed +OXT OT, OT-NPI, OXT-NPI ENSG00000101405 Oxytocin/neurophysin I prepropeptide 20 3071620-3072517 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA071892 Supported Supported Tissue enriched Tissue enhanced liver: 2.1;small intestine: 1.1 duodenum: 1.1 Cell line enhanced CACO-2: 1.3;HMC-1: 1.0 +TTI1 KIAA0406, smg-10 ENSG00000101407 TELO2 interacting protein 1 20 37983007-38033468 Predicted intracellular proteins Evidence at protein level CAB034230, HPA068338 Uncertain Approved Nucleoplasm
Vesicles Liver cancer:2.40e-7 (unfavourable), Endometrial cancer:3.30e-5 (unfavourable) Expressed in all Expressed in all testis,thyroid gland: 20.3 Expressed in all +E2F1 RBBP3, RBP3 ENSG00000101412 E2F transcription factor 1 20 33675683-33686404 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000329, HPA008003, CAB019308, HPA029735 Enhanced Enhanced Nucleoplasm
Centrosome Cervical cancer:9.22e-6 (favourable), Liver cancer:3.83e-5 (unfavourable), Endometrial cancer:4.33e-5 (unfavourable), Renal cancer:8.99e-5 (unfavourable), Thyroid cancer:1.62e-4 (favourable), Pancreatic cancer:4.18e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 22.9 testis: 12.7 Mixed +RPRD1B C20orf77, CREPT, dJ1057B20.2, DKFZp434P0735, FLJ44520, NET60 ENSG00000101413 Regulation of nuclear pre-mRNA domain containing 1B 20 38033546-38127780 Predicted intracellular proteins Evidence at protein level HPA066290 Supported Supported Nucleoplasm
Centrosome
Cytosol Expressed in all Expressed in all parathyroid gland: 29.6 Expressed in all +PXMP4 PMP24 ENSG00000101417 Peroxisomal membrane protein 4 20 33702754-33720319 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA050077 Approved Approved Nucleoli fibrillar center
Peroxisomes Renal cancer:4.03e-10 (favourable), Lung cancer:3.88e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.1 Cell line enhanced SK-BR-3: 56.7;T-47d: 60.1 +CHMP4B C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B ENSG00000101421 Charged multivesicular body protein 4B 20 33811304-33854366 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041401, HPA051751 Enhanced Liver cancer:5.10e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 140.4 Expressed in all +BPI BPIFD1 ENSG00000101425 Bactericidal/permeability-increasing protein 20 38260149-38337505 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA061284 Enhanced Not detected Tissue enriched 37 bone marrow: 961.6 testis: 25.9 Group enriched 5 AF22: 2.3;ASC diff: 1.1;ASC TERT1: 3.1;BJ: 2.1;BJ hTERT+: 2.1;HL-60: 1.1 +CST9L bA218C14.1, CTES7B ENSG00000101435 Cystatin 9-like 20 23564732-23568749 Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 6 testis: 108.4 epididymis: 19.6 Cell line enriched 13 HEL: 1.2 +SLC32A1 bA122O1.1, VGAT, VIAAT ENSG00000101438 Solute carrier family 32 member 1 20 38724462-38729372 Predicted membrane proteins, Transporters Evidence at protein level CAB037156, HPA058859, HPA059985 Enhanced Supported Tissue enhanced Tissue enriched 35 cerebral cortex: 15.9 testis: 0.4 Cell line enhanced MOLT-4: 1.1 +CST3 ENSG00000101439 Cystatin C 20 23626706-23638473 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000118, HPA013143 Enhanced Supported Golgi apparatus
Vesicles Endometrial cancer:1.83e-4 (favourable), Urothelial cancer:8.77e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1265.8 Cell line enhanced ASC diff: 1105.8 +ASIP AGTIL, ASP ENSG00000101440 Agouti signaling protein 20 34194569-34269344 Predicted secreted proteins Evidence at protein level HPA048636 Uncertain Supported Vesicles Mixed Group enriched 5 epididymis: 18.1;ovary: 7.4;skin: 5.7 breast: 2.0 Cell line enhanced CACO-2: 2.6 +CST4 ENSG00000101441 Cystatin S 20 23685640-23689040 Predicted secreted proteins Evidence at protein level HPA043706, HPA044763 Supported Ovarian cancer:4.98e-5 (unfavourable), Urothelial cancer:2.88e-4 (favourable) Mixed Tissue enriched 113 salivary gland: 9926.9 gallbladder: 87.6 Cell line enhanced CACO-2: 4.5;hTEC/SVTERT24-B: 2.1;RT4: 10.7;TIME: 1.8 +ACTR5 Arp5, FLJ12785, INO80M ENSG00000101442 ARP5 actin-related protein 5 homolog 20 38748442-38772520 Predicted intracellular proteins Evidence at protein level HPA042676 Approved Liver cancer:1.84e-5 (unfavourable), Renal cancer:1.37e-4 (unfavourable) Expressed in all Mixed testis: 16.5 Expressed in all +WFDC2 dJ461P17.6, EDDM4, HE4, WAP5 ENSG00000101443 WAP four-disulfide core domain 2 20 45469706-45481532 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042302 Enhanced Approved Cytosol Renal cancer:4.44e-5 (favourable), Glioma:5.87e-5 (unfavourable) Expressed in all Tissue enriched 6 cervix, uterine: 6567.2 seminal vesicle: 1051.7 Group enriched 8 A-431: 90.4;CAPAN-2: 165.0;EFO-21: 144.7;HaCaT: 121.3;RPTEC TERT1: 108.5 +AHCY SAHH ENSG00000101444 Adenosylhomocysteinase 20 34280268-34311802 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041225, HPA044675 Approved Supported Cytosol Expressed in all Expressed in all kidney: 159.4 Expressed in all +PPP1R16B ANKRD4, KIAA0823, TIMAP ENSG00000101445 Protein phosphatase 1 regulatory subunit 16B 20 38805705-38923024 Predicted intracellular proteins Evidence at protein level HPA049571 Supported Nuclear speckles
Plasma membrane Head and neck cancer:7.87e-5 (favourable), Cervical cancer:2.11e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 50.9 lymph node: 44.2 Cell line enhanced Daudi: 40.9;HMC-1: 52.2;HUVEC TERT2: 29.7;U-266/70: 73.8;U-266/84: 29.1 +SPINT3 HKIB9 ENSG00000101446 Serine peptidase inhibitor, Kunitz type 3 20 45512461-45515624 Predicted secreted proteins Evidence at protein level HPA026852 Enhanced Not detected Group enriched 32 epididymis: 5.8;seminal vesicle: 15.4 skin: 0.3 Not detected +FAM83D C20orf129, CHICA, dJ616B8.3 ENSG00000101447 Family with sequence similarity 83 member D 20 38926312-38953106 Predicted intracellular proteins Evidence at protein level Renal cancer:1.81e-14 (unfavourable), Liver cancer:5.44e-6 (unfavourable), Pancreatic cancer:4.73e-5 (unfavourable), Endometrial cancer:1.49e-4 (unfavourable), Lung cancer:9.69e-4 (unfavourable) Mixed Tissue enhanced esophagus: 76.1;smooth muscle: 131.9 prostate: 21.8 Expressed in all +EPPIN CT71, dJ461P17.2, EPPIN1, EPPIN2, EPPIN3, SPINLW1, WAP7, WFDC7 ENSG00000101448 Epididymal peptidase inhibitor 20 45540626-45547752 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Not detected Group enriched 117 epididymis: 414.2;testis: 128.4 fallopian tube: 2.3 Cell line enhanced U-87 MG: 2.6 +DHX35 C20orf15, DDX35, FLJ22759, KAIA0875 ENSG00000101452 DEAH-box helicase 35 20 38962299-39039723 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054451, HPA062700 Uncertain Approved Nucleus
Nuclear bodies
Centrosome Liver cancer:5.63e-6 (unfavourable), Endometrial cancer:4.25e-5 (unfavourable) Expressed in all Mixed endometrium: 14.9 Expressed in all +DNTTIP1 C20orf167, dJ447F3.4, Tdif1 ENSG00000101457 Deoxynucleotidyltransferase terminal interacting protein 1 20 45791937-45811427 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042479, HPA045496 Enhanced Nucleus Renal cancer:1.90e-6 (unfavourable), Liver cancer:1.79e-5 (unfavourable) Expressed in all Expressed in all testis: 44.6 Expressed in all +MAP1LC3A ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3 ENSG00000101460 Microtubule associated protein 1 light chain 3 alpha 20 34546854-34560345 Predicted intracellular proteins Evidence at protein level HPA007649, CAB037174, HPA052474, HPA052484 Enhanced Pancreatic cancer:5.31e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 119.1 Cell line enhanced HSkMC: 49.9;SCLC-21H: 52.4;SK-BR-3: 46.8 +SYNDIG1 C20orf39, FLJ14220, IFITMD5, SynDIG1, TMEM90B ENSG00000101463 Synapse differentiation inducing 1 20 24469199-24666616 Predicted membrane proteins Evidence at protein level HPA044271, HPA059267 Supported Vesicles Thyroid cancer:6.16e-6 (unfavourable) Mixed Tissue enhanced cerebral cortex: 26.9 heart muscle: 14.4 Group enriched 9 Karpas-707: 9.0;RH-30: 34.5;RPMI-8226: 24.4;SCLC-21H: 9.7;U-87 MG: 21.0 +PIGU bA346K17.2, CDC91L1, GAB1 ENSG00000101464 Phosphatidylinositol glycan anchor biosynthesis class U 20 34560542-34698790 Predicted membrane proteins Evidence at protein level HPA041706, HPA046766 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:1.49e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 48.2 Expressed in all +TNNC2 ENSG00000101470 Troponin C2, fast skeletal type 20 45823214-45833745 Predicted intracellular proteins Evidence at protein level HPA043174, HPA058481 Enhanced Approved Nucleoplasm
Vesicles Mixed Tissue enriched 78 skeletal muscle: 9898.9 esophagus: 126.3 Group enriched 6 Hep G2: 6.4;HSkMC: 10.1;SCLC-21H: 12.6 +ACOT8 hACTE-III, hTE, NAP1, PTE-2, PTE1 ENSG00000101473 Acyl-CoA thioesterase 8 20 45841721-45857406 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010261 Approved Supported Vesicles
Mitochondria Renal cancer:3.18e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 30.1 Expressed in all +APMAP BSCv, C20orf3 ENSG00000101474 Adipocyte plasma membrane associated protein 20 24962925-24992979 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012863, HPA064700 Uncertain Approved Plasma membrane Expressed in all Expressed in all thyroid gland: 323.5 Expressed in all +CELF4 BRUNOL4 ENSG00000101489 CUGBP Elav-like family member 4 18 37243047-37566037 Predicted intracellular proteins Evidence at protein level HPA037986 Approved Mixed Tissue enriched 9 cerebral cortex: 126.9 adrenal gland: 14.7 Group enriched 15 SCLC-21H: 51.8;SH-SY5Y: 11.4 +ZNF516 HsT287, KIAA0222 ENSG00000101493 Zinc finger protein 516 18 76358190-76495190 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015792 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.21e-4 (favourable), Liver cancer:2.79e-4 (unfavourable), Breast cancer:7.09e-4 (favourable), Pancreatic cancer:7.96e-4 (favourable) Expressed in all Expressed in all endometrium: 54.4 Mixed +CDH20 Cdh7, CDH7L3 ENSG00000101542 Cadherin 20 18 61333582-61555773 Predicted membrane proteins Evidence at protein level HPA015490 Uncertain Tissue enriched Tissue enriched 5 cerebral cortex: 26.8 adipose tissue: 4.9 Cell line enhanced AF22: 1.8;ASC diff: 3.9;HHSteC: 2.2;SH-SY5Y: 4.1 +ADNP2 KIAA0863, ZNF508 ENSG00000101544 ADNP homeobox 2 18 80109031-80147523 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007126 Uncertain Approved Mitochondria
Cytosol Renal cancer:6.39e-5 (favourable), Thyroid cancer:9.90e-4 (unfavourable) Expressed in all Mixed testis: 39.7 Mixed +RBFA C18orf22, FLJ21172, HsT169 ENSG00000101546 Ribosome binding factor A (putative) 18 80034358-80046397 Predicted intracellular proteins Evidence at protein level HPA040485, HPA041479 Approved Supported Mitochondria Liver cancer:2.06e-6 (unfavourable) Expressed in all Expressed in all adipose tissue: 20.3 Expressed in all +USP14 TGT ENSG00000101557 Ubiquitin specific peptidase 14 18 158383-214629 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001308 Approved Supported Cytosol Liver cancer:4.30e-5 (unfavourable), Head and neck cancer:7.81e-5 (unfavourable), Ovarian cancer:7.91e-4 (favourable) Expressed in all Expressed in all prostate: 48.2 Expressed in all +VAPA hVAP-33, VAP-A ENSG00000101558 VAMP associated protein A 18 9914002-9960021 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA009174 Approved Enhanced Endoplasmic reticulum Renal cancer:5.72e-7 (favourable) Expressed in all Expressed in all adrenal gland: 61.3 Expressed in all +METTL4 FLJ23017, HsT661 ENSG00000101574 Methyltransferase like 4 18 2537525-2571509 Predicted intracellular proteins Evidence at protein level HPA040061, HPA046734 Approved Approved Mitochondria Expressed in all Expressed in all thyroid gland: 17.3 Expressed in all +LPIN2 KIAA0249 ENSG00000101577 Lipin 2 18 2916994-3013315 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB015223, HPA017857, HPA030550 Enhanced Supported Plasma membrane
Actin filaments
Cytosol Head and neck cancer:8.01e-4 (favourable) Expressed in all Mixed liver: 87.3 Mixed +SMCHD1 FSHD2, KIAA0650 ENSG00000101596 Structural maintenance of chromosomes flexible hinge domain containing 1 18 2655738-2805017 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039441 Approved Approved Nucleoplasm
Nuclear bodies Renal cancer:1.40e-4 (unfavourable), Liver cancer:5.39e-4 (unfavourable) Expressed in all Expressed in all spleen: 40.5 Expressed in all +MYOM1 ENSG00000101605 Myomesin 1 18 3066807-3220108 Predicted intracellular proteins Evidence at protein level HPA014305, HPA049193 Enhanced Tissue enhanced Group enriched 13 heart muscle: 278.1;skeletal muscle: 299.1 gallbladder: 22.9 Group enriched 12 HAP1: 13.8;HMC-1: 3.1;HSkMC: 4.5 +MYL12A MLCB, MRCL3, MRLC3, MYL2B ENSG00000101608 Myosin light chain 12A 18 3247481-3256236 Predicted intracellular proteins Evidence at protein level CAB004503, HPA039262, HPA045244, HPA059197 Supported Approved Nucleus
Nucleoli fibrillar center Expressed in all Expressed in all heart muscle: 2635.3 Expressed in all +CEP76 C18orf9, FLJ12542, HsT1705 ENSG00000101624 Centrosomal protein 76 18 12661833-12702777 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA039395 Approved Expressed in all Mixed testis: 14.7 Expressed in all +ST8SIA5 SIAT8E ENSG00000101638 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 18 46667821-46759257 Predicted membrane proteins Evidence at protein level HPA043813, HPA046771 Approved Approved Plasma membrane
Midbody Tissue enriched Tissue enhanced adrenal gland: 5.5;cerebral cortex: 11.4 parathyroid gland: 3.4 Cell line enriched 7 WM-115: 121.0 +CEP192 FLJ10352, KIAA1569, PPP1R62 ENSG00000101639 Centrosomal protein 192 18 12991362-13125052 Predicted intracellular proteins Evidence at protein level HPA039392, HPA040503 Uncertain Approved Centrosome
Cytosol Expressed in all Mixed testis: 17.3 Expressed in all +RNMT RG7MT1 ENSG00000101654 RNA guanine-7 methyltransferase 18 13726660-13764558 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039409 Approved Enhanced Nucleoplasm Expressed in all Expressed in all testis: 31.0 Expressed in all +SMAD7 MADH7, MADH8 ENSG00000101665 SMAD family member 7 18 48919853-48950711 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026212, HPA028897 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:5.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.0 Mixed +LIPG EDL ENSG00000101670 Lipase G, endothelial type 18 49560699-49599182 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA016966 Uncertain Tissue enriched Group enriched 11 placenta: 214.4;thyroid gland: 403.2 seminal vesicle: 29.1 Cell line enhanced AN3-CA: 113.7;HaCaT: 167.5;RPTEC TERT1: 93.8;TIME: 201.4 +LAMA1 LAMA ENSG00000101680 Laminin subunit alpha 1 18 6941744-7117814 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010179 Enhanced Mixed Tissue enhanced testis: 11.2 thyroid gland: 4.3 Cell line enhanced AF22: 55.1;BEWO: 192.1 +RNF125 FLJ20456 ENSG00000101695 Ring finger protein 125 18 32018372-32073213 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041514 Uncertain Uncertain Nucleoli
Golgi apparatus
Cytosol Renal cancer:4.06e-4 (unfavourable) Expressed in all Mixed small intestine: 11.5 Cell line enhanced HMC-1: 42.3 +ANKRD12 FLJ20053, GAC-1, KIAA0874 ENSG00000101745 Ankyrin repeat domain 12 18 9136228-9285985 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA040705 Approved Supported Nucleoplasm
Cytosol Melanoma:6.71e-4 (unfavourable) Expressed in all Expressed in all testis: 52.0 Expressed in all +NOL4 CT125, HRIHFB2255, NOLP ENSG00000101746 Nucleolar protein 4 18 33851100-34224952 Predicted intracellular proteins Evidence at protein level HPA046740 Supported Nucleus Tissue enhanced Group enriched 7 cerebral cortex: 15.9;testis: 22.8 thyroid gland: 2.9 Cell line enhanced SCLC-21H: 44.1;SH-SY5Y: 10.6;U-698: 5.7 +POLI RAD30B, RAD3OB ENSG00000101751 DNA polymerase iota 18 54269404-54321266 Enzymes, Predicted intracellular proteins Evidence at protein level HPA012000, HPA064696 Enhanced Supported Nuclear speckles
Cytoplasmic bodies Expressed in all Expressed in all testis: 69.7 Expressed in all +MIB1 DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6 ENSG00000101752 Mindbomb E3 ubiquitin protein ligase 1 18 21704957-21870957 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019100, CAB037044 Approved Approved Nuclear membrane
Vesicles
Plasma membrane Expressed in all Expressed in all thyroid gland: 24.2 Expressed in all +RBBP8 COM1, CtIP, RIM, SCKL2 ENSG00000101773 RB binding protein 8, endonuclease 18 22798261-23026488 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039890, HPA052946 Approved Supported Nucleoplasm Renal cancer:1.71e-5 (favourable), Melanoma:7.21e-4 (unfavourable) Expressed in all Mixed testis: 52.7 Expressed in all +RIOK3 SUDD ENSG00000101782 RIO kinase 3 18 23452823-23486603 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001620, HPA024184 Approved Approved Golgi apparatus
Plasma membrane
Microtubule organizing center
Cytosol Pancreatic cancer:4.10e-4 (unfavourable), Prostate cancer:5.80e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 74.9 Expressed in all +CSTF2 CstF-64 ENSG00000101811 Cleavage stimulation factor subunit 2 X 100820359-100840932 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000427, CAB004680 Enhanced Enhanced Nucleoplasm
Nuclear bodies Liver cancer:8.23e-6 (unfavourable), Renal cancer:1.12e-4 (favourable) Expressed in all Mixed testis: 25.7 Expressed in all +H2BFM ENSG00000101812 H2B histone family member M X 104039949-104042454 Predicted intracellular proteins Evidence at protein level Not detected Mixed testis: 2.4 Mixed +MXRA5 DKFZp564I1922 ENSG00000101825 Matrix remodeling associated 5 X 3308565-3346641 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level HPA000508 Uncertain Uncertain Mitochondria Glioma:2.56e-4 (unfavourable), Urothelial cancer:8.94e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 57.1 skin: 35.2 Cell line enhanced BJ hTERT+: 102.1;fHDF/TERT166: 46.4;HaCaT: 46.3 +VSIG1 MGC44287 ENSG00000101842 V-set and immunoglobulin domain containing 1 X 108044970-108079184 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA001445, HPA036310, HPA036311 Enhanced Approved Vesicles
Cytosol Group enriched Group enriched 10 stomach: 185.7;testis: 91.1 gallbladder: 14.3 Cell line enhanced HBEC3-KT: 2.5;HUVEC TERT2: 5.9;PC-3: 2.2 +PSMD10 p28 ENSG00000101843 Proteasome 26S subunit, non-ATPase 10 X 108084207-108091618 Predicted intracellular proteins Evidence at protein level HPA002920, CAB010434 Approved Supported Intermediate filaments
Cytosol Expressed in all Expressed in all cerebral cortex: 70.0 Expressed in all +ATG4A APG4A, AUTL2 ENSG00000101844 Autophagy related 4A cysteine peptidase X 108091668-108154671 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036374, HPA064759 Uncertain Approved Actin filaments
Microtubules Breast cancer:1.36e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 17.8 Expressed in all +STS ARSC, ARSC1 ENSG00000101846 Steroid sulfatase X 7219456-7354810 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA002904 Enhanced Pancreatic cancer:3.47e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 36.5 adipose tissue: 18.9 Cell line enhanced U-266/70: 79.0 +TBL1X EBI, TBL1 ENSG00000101849 Transducin beta like 1X-linked X 9463295-9719743 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005363, HPA067703 Approved Approved Nucleus
Nucleoli Pancreatic cancer:1.32e-4 (favourable), Renal cancer:4.58e-4 (favourable), Breast cancer:8.50e-4 (unfavourable) Expressed in all Expressed in all endometrium: 63.9 Mixed +GPR143 OA1 ENSG00000101850 G protein-coupled receptor 143 X 9725346-9786297 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA003648 Enhanced Renal cancer:2.45e-5 (favourable), Cervical cancer:8.73e-4 (favourable) Tissue enriched Mixed skin: 10.3 Cell line enriched 7 SK-MEL-30: 119.4 +PGRMC1 HPR6.6 ENSG00000101856 Progesterone receptor membrane component 1 X 119236245-119244466 Predicted membrane proteins Evidence at protein level HPA002877 Enhanced Approved Nucleoli
Endoplasmic reticulum Head and neck cancer:3.02e-4 (unfavourable) Expressed in all Expressed in all liver: 339.9 Expressed in all +POLA1 NSX, p180, POLA ENSG00000101868 DNA polymerase alpha 1, catalytic subunit X 24693919-24996986 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA002947, CAB012274 Enhanced Supported Nucleoplasm
Cytosol Liver cancer:4.80e-5 (unfavourable) Expressed in all Mixed lymph node: 8.7 Expressed in all +MID1 FXY, OS, RNF59, TRIM18 ENSG00000101871 Midline 1 X 10445310-10833654 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003715 Approved Liver cancer:3.06e-4 (unfavourable) Expressed in all Mixed seminal vesicle: 20.7 Cell line enhanced A549: 168.3;AF22: 136.2 +NKAP FLJ22626 ENSG00000101882 NFKB activating protein X 119920672-119943772 Predicted intracellular proteins Evidence at protein level HPA000916 Supported Supported Nucleoplasm
Cytosol Breast cancer:4.20e-4 (unfavourable) Expressed in all Mixed ovary: 6.5 Expressed in all +RHOXF1 OTEX, PEPP1 ENSG00000101883 Rhox homeobox family member 1 X 120109053-120115937 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056506 Approved Mixed Tissue enriched 9 testis: 15.5 adipose tissue: 1.6 Not detected +NXT2 P15-2 ENSG00000101888 Nuclear transport factor 2 like export factor 2 X 109535781-109544690 Predicted intracellular proteins Evidence at protein level HPA024199, HPA072010 Approved Supported Nucleoplasm
Cytosol Expressed in all Mixed testis: 52.0 Expressed in all +GUCY2F CYGF, GC-F, GUC2DL, RetGC-2, ROS-GC2 ENSG00000101890 Guanylate cyclase 2F, retinal X 109372906-109482072 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level Not detected Not detected fallopian tube,testis: 0.4 Not detected +ATP1B4 ENSG00000101892 ATPase Na+/K+ transporting family member beta 4 X 120362085-120383249 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 9 skeletal muscle: 20.5 prostate: 2.3 Not detected +ALG13 CDG1S, CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W ENSG00000101901 ALG13, UDP-N-acetylglucosaminyltransferase subunit X 111665811-111760649 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002853 Approved Renal cancer:1.10e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 30.4 Expressed in all +PRPS2 ENSG00000101911 Phosphoribosyl pyrophosphate synthetase 2 X 12791355-12824222 Enzymes, Predicted intracellular proteins Evidence at protein level HPA067599, CAB070417 Enhanced Approved Vesicles Cervical cancer:1.90e-4 (favourable) Expressed in all Tissue enhanced testis: 242.3 seminal vesicle: 117.1 Expressed in all +TLR8 CD288 ENSG00000101916 Toll like receptor 8 X 12906620-12923169 CD markers, Predicted membrane proteins Evidence at protein level HPA001608 Enhanced Mixed Tissue enhanced appendix: 23.2;lung: 15.6;spleen: 18.3 lymph node: 6.6 Not detected +MOSPD1 dJ473B4 ENSG00000101928 Motile sperm domain containing 1 X 134887626-134915267 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031158 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all fallopian tube: 42.4 Expressed in all +AMMECR1 ENSG00000101935 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 X 110194186-110440233 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000590, HPA051762 Uncertain Ovarian cancer:6.62e-5 (favourable), Thyroid cancer:8.44e-4 (favourable) Expressed in all Mixed placenta: 9.8 Expressed in all +CHRDL1 CHL, MGC1, NRLN1 ENSG00000101938 Chordin like 1 X 110673856-110795819 Disease related genes, Predicted secreted proteins Evidence at protein level HPA000226, HPA000250 Approved Urothelial cancer:2.23e-4 (unfavourable), Renal cancer:2.36e-4 (unfavourable) Mixed Tissue enhanced seminal vesicle: 386.7 parathyroid gland: 315.6 Group enriched 8 ASC diff: 446.8;ASC TERT1: 622.4 +WDR13 ENSG00000101940 WD repeat domain 13 X 48590042-48608867 Predicted intracellular proteins Evidence at protein level HPA000913 Enhanced Supported Nucleoplasm
Plasma membrane
Microtubule organizing center Expressed in all Expressed in all fallopian tube: 91.9 Expressed in all +SUV39H1 KMT1A, SUV39H ENSG00000101945 Suppressor of variegation 3-9 homolog 1 X 48695554-48709012 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:1.91e-7 (unfavourable), Cervical cancer:8.93e-5 (favourable) Expressed in all Mixed epididymis: 14.4 Expressed in all +PAGE4 CT16.7, GAGEC1, PAGE-4 ENSG00000101951 PAGE family member 4 X 49829260-49833973 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA023880 Enhanced Approved Golgi apparatus
Vesicles Group enriched Group enriched 6 epididymis: 1456.6;placenta: 2041.1 prostate: 269.4 Group enriched 9 CACO-2: 8.5;U-266/70: 9.3;U-266/84: 33.4 +SRPX ETX1 ENSG00000101955 Sushi repeat containing protein, X-linked X 38149336-38220924 Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:7.80e-13 (unfavourable), Endometrial cancer:1.18e-4 (unfavourable), Urothelial cancer:3.36e-4 (unfavourable) Group enriched Tissue enhanced adipose tissue: 162.7 placenta: 122.1 Cell line enhanced ASC diff: 2526.0;ASC TERT1: 571.9;HSkMC: 899.7;HUVEC TERT2: 659.1 +GLRA2 GLR ENSG00000101958 Glycine receptor alpha 2 X 14529298-14731812 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB070422 Approved Mixed Group enriched 10 cerebral cortex: 6.1;colon: 1.4;rectum: 4.3 testis: 0.3 Cell line enriched 41 AN3-CA: 16.1 +XIAP API3, BIRC4, hILP ENSG00000101966 X-linked inhibitor of apoptosis X 123859724-123913979 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB009203, HPA042428 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Breast cancer:9.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.4 Mixed +STAG2 SA-2, SA2, SCC3B ENSG00000101972 Stromal antigen 2 X 123960212-124422664 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002857 Supported Expressed in all Expressed in all parathyroid gland: 112.2 Mixed +ATP11C ATPIG, ATPIQ ENSG00000101974 ATPase phospholipid transporting 11C X 139726346-139945276 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA030830 Approved Expressed in all Mixed liver: 25.6 Mixed +MCF2 ARHGEF21, DBL ENSG00000101977 MCF.2 cell line derived transforming sequence X 139581770-139708227 Plasma proteins, Predicted intracellular proteins Evidence at protein level Not detected Group enriched 11 adrenal gland: 38.3;cerebral cortex: 8.7;epididymis: 15.0;ovary: 12.9;seminal vesicle: 24.0;testis: 34.6 prostate: 2.0 Cell line enriched 12 U-251 MG: 30.6 +F9 FIX ENSG00000101981 Coagulation factor IX X 139530758-139563458 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Liver cancer:6.69e-4 (favourable) Tissue enriched Tissue enriched 2258 liver: 365.0 kidney: 0.1 Not detected +ABCD1 adrenoleukodystrophy, ALD, ALDP, AMN ENSG00000101986 ATP binding cassette subfamily D member 1 X 153724868-153744762 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:5.50e-4 (unfavourable) Expressed in all Expressed in all small intestine: 19.3 Cell line enhanced EFO-21: 65.5;PC-3: 46.4 +CCDC22 CXorf37, JM1 ENSG00000101997 Coiled-coil domain containing 22 X 49235467-49250526 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000229, HPA000888 Uncertain Approved Approved Nucleoplasm
Cytosol Liver cancer:2.17e-4 (unfavourable) Expressed in all Expressed in all spleen: 18.4 Expressed in all +CACNA1F AIED, Cav1.4, CORDX3, CSNB2, CSNB2A, CSNBX2, JM8, JMC8, OA2 ENSG00000102001 Calcium voltage-gated channel subunit alpha1 F X 49205063-49233371 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA068379 Supported Not detected Mixed lymph node: 1.6 Cell line enhanced U-266/70: 1.0 +SYP MRX96 ENSG00000102003 Synaptophysin X 49187804-49200259 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB000076, HPA002858, CAB055505, CAB078999 Enhanced Supported Group enriched Tissue enriched 11 cerebral cortex: 571.4 adrenal gland: 51.1 Cell line enhanced SCLC-21H: 116.7;SH-SY5Y: 38.0 +PLP2 A4, A4-LSB, MGC126187 ENSG00000102007 Proteolipid protein 2 X 49171926-49175239 Predicted membrane proteins, Transporters Evidence at protein level HPA042415 Approved Renal cancer:5.55e-10 (unfavourable), Endometrial cancer:3.32e-5 (unfavourable) Expressed in all Expressed in all skin: 480.2 Mixed +BMX ETK, PSCTK3 ENSG00000102010 BMX non-receptor tyrosine kinase X 15464246-15556529 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001048, CAB032495 Enhanced Supported Nucleoplasm
Plasma membrane Mixed Tissue enriched 18 epididymis: 125.0 placenta: 6.9 Cell line enriched 125 HUVEC TERT2: 295.8 +LUZP4 CT-8, CT28, HOM-TES-85 ENSG00000102021 Leucine zipper protein 4 X 115289727-115307556 Predicted intracellular proteins Evidence at protein level HPA046436, HPA051999 Enhanced Tissue enriched Tissue enriched 157 testis: 15.7 all non-specific tissues: 0.0 Not detected +PLS3 T-plastin ENSG00000102024 Plastin 3 X 115561174-115650861 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020433, HPA076083 Enhanced Approved Plasma membrane
Cytosol Head and neck cancer:6.07e-5 (unfavourable), Renal cancer:1.01e-4 (unfavourable), Thyroid cancer:3.72e-4 (favourable), Pancreatic cancer:4.59e-4 (unfavourable), Urothelial cancer:7.04e-4 (unfavourable) Expressed in all Mixed thyroid gland: 293.0 Mixed +NAA10 ARD1, ARD1A, DXS707, TE2 ENSG00000102030 N(alpha)-acetyltransferase 10, NatA catalytic subunit X 153929242-153935223 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB006269, HPA030711 Supported Enhanced Nucleoli
Cytosol Renal cancer:3.29e-8 (unfavourable) Expressed in all Expressed in all smooth muscle: 25.7 Expressed in all +RENBP RBP, RNBP ENSG00000102032 Renin binding protein X 153935263-153944691 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000428, HPA000522 Enhanced Renal cancer:3.08e-5 (favourable), Cervical cancer:3.95e-4 (favourable) Expressed in all Tissue enhanced spleen: 58.5 kidney: 37.8 Cell line enhanced EFO-21: 31.9;HMC-1: 101.6;SK-MEL-30: 61.5;U-266/84: 49.9 +ELF4 ELFR, MEF ENSG00000102034 E74 like ETS transcription factor 4 X 130064874-130110716 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058595, HPA060277 Enhanced Supported Nucleoplasm
Nuclear bodies Renal cancer:6.49e-6 (unfavourable), Urothelial cancer:1.42e-4 (favourable) Expressed in all Mixed placenta: 34.9 Mixed +SMARCA1 hSNF2L, ISWI, NURF140, SNF2L, SNF2L1, SNF2LB, SWI ENSG00000102038 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 X 129446501-129523500 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003335, HPA064712 Uncertain Supported Nucleoplasm
Vesicles Pancreatic cancer:3.03e-4 (favourable), Renal cancer:5.09e-4 (favourable) Expressed in all Mixed testis: 113.1 Mixed +MTMR8 FLJ20126 ENSG00000102043 Myotubularin related protein 8 X 64268081-64395431 Predicted intracellular proteins Evidence at protein level Mixed Mixed fallopian tube: 3.7 Cell line enhanced NTERA-2: 4.3 +ASB9 DKFZP564L0862, FLJ20636, MGC4954 ENSG00000102048 Ankyrin repeat and SOCS box containing 9 X 15235288-15270467 Predicted intracellular proteins Evidence at protein level HPA003014, HPA003060, CAB004997 Enhanced Prostate cancer:4.36e-4 (unfavourable) Expressed in all Tissue enhanced testis: 48.3 kidney: 16.9 Cell line enhanced A549: 23.1;PC-3: 48.9 +ZC3H12B CXorf32, MCPIP2 ENSG00000102053 Zinc finger CCCH-type containing 12B X 65366638-65507887 Predicted intracellular proteins Evidence at transcript level HPA000836 Uncertain Approved Endoplasmic reticulum
Golgi apparatus
Vesicles Mixed Tissue enhanced cerebral cortex: 4.6 endometrium: 2.2 Cell line enhanced AF22: 2.1 +RBBP7 RbAp46 ENSG00000102054 RB binding protein 7, chromatin remodeling factor X 16839283-16870414 Predicted intracellular proteins Evidence at protein level CAB037084, HPA060710, HPA060724 Supported Thyroid cancer:2.43e-4 (favourable), Liver cancer:5.55e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 376.0 Expressed in all +PPP1R2P9 I-4 ENSG00000102055 Protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 9 X 42777368-42778247 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 584 testis: 60.2 lymph node,tonsil: 0.1 Not detected +KCND1 Kv4.1 ENSG00000102057 Potassium voltage-gated channel subfamily D member 1 X 48961378-48971569 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA000524, HPA001066 Approved Approved Nucleus Pancreatic cancer:2.66e-6 (favourable) Mixed Mixed gallbladder: 3.9 Mixed +OPN1LW CBBM, CBP, COD5, RCP ENSG00000102076 Opsin 1, long wave sensitive X 154144224-154159032 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Not detected Not detected testis: 0.1 Not detected +SLC25A14 BMCP1, UCP5 ENSG00000102078 Solute carrier family 25 member 14 X 130339888-130373361 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA060316 Approved Mitochondria Renal cancer:5.52e-6 (unfavourable), Urothelial cancer:1.39e-5 (favourable), Cervical cancer:1.72e-5 (favourable), Pancreatic cancer:1.78e-4 (favourable) Expressed in all Mixed cerebral cortex: 20.4 Expressed in all +FMR1 FMRP, FRAXA, MGC87458, POF, POF1 ENSG00000102081 Fragile X mental retardation 1 X 147911951-147951125 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB012444, HPA050118, HPA056084 Approved Enhanced Cytosol Endometrial cancer:1.32e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 55.4 Expressed in all +PIM2 ENSG00000102096 Pim-2 proto-oncogene, serine/threonine kinase X 48913182-48919024 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000285 Approved Cytosol Renal cancer:1.17e-11 (unfavourable), Cervical cancer:4.05e-5 (favourable) Tissue enriched Mixed lymph node: 128.7 Expressed in all +SCML2 ENSG00000102098 Sex comb on midleg-like 2 (Drosophila) X 18239314-18354727 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001662, HPA064713 Enhanced Approved Nucleoli
Cytosol Mixed Tissue enhanced testis: 19.2 ovary: 6.3 Cell line enhanced NTERA-2: 35.7 +SLC35A2 UGALT, UGAT, UGT, UGT1, UGT2, UGTL ENSG00000102100 Solute carrier family 35 member A2 X 48903180-48911958 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA036087 Approved Supported Golgi apparatus Liver cancer:9.64e-5 (unfavourable), Breast cancer:3.16e-4 (unfavourable), Stomach cancer:8.23e-4 (favourable) Expressed in all Expressed in all fallopian tube: 45.0 Expressed in all +PQBP1 MRX2, MRX55, MRXS3, MRXS8, RENS1, SHS ENSG00000102103 Polyglutamine binding protein 1 X 48897912-48903143 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001880 Supported Enhanced Nuclear speckles Renal cancer:2.68e-7 (unfavourable), Cervical cancer:1.48e-4 (favourable) Expressed in all Expressed in all fallopian tube,ovary: 49.9 Expressed in all +RS1 RS, XLRS1 ENSG00000102104 Retinoschisin 1 X 18639910-18672109 Disease related genes, Predicted secreted proteins Evidence at protein level HPA059546 Supported Not detected Group enriched 7 cerebral cortex: 1.1;lung: 1.6 lymph node,spleen,thyroid gland: 0.1 Not detected +PCSK1N BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII ENSG00000102109 Proprotein convertase subtilisin/kexin type 1 inhibitor X 48831094-48835633 Predicted secreted proteins Evidence at protein level HPA003925, HPA064734 Enhanced Approved Vesicles Endometrial cancer:1.15e-4 (unfavourable), Renal cancer:1.36e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 93.6;kidney: 65.7 adrenal gland: 28.5 Cell line enhanced HEK 293: 52.2;PC-3: 133.3;SCLC-21H: 66.4;SH-SY5Y: 55.2;SiHa: 53.6;U-266/84: 49.2 +EMD LEMD5, STA ENSG00000102119 Emerin X 154379197-154381523 Disease related genes, Predicted membrane proteins Evidence at protein level HPA000609, CAB001545, CAB002029, CAB062552 Enhanced Enhanced Nuclear membrane
Endoplasmic reticulum Expressed in all Expressed in all fallopian tube: 32.7 Expressed in all +TAZ BTHS, CMD3A, EFE, EFE2, G4.5, TAZ1, XAP-2 ENSG00000102125 Tafazzin X 154411518-154421726 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039557 Approved Approved Plasma membrane Renal cancer:1.22e-7 (unfavourable), Cervical cancer:5.70e-4 (favourable) Expressed in all Expressed in all bone marrow,spleen: 20.8 Expressed in all +RAB40AL RAR2, RLGP ENSG00000102128 RAB40A, member RAS oncogene family-like X 102937272-102938300 Disease related genes, Predicted intracellular proteins Evidence at protein level Not detected Not detected epididymis: 0.3 Not detected +PGK1 ENSG00000102144 Phosphoglycerate kinase 1 X 78065188-78129296 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB010065, HPA045385, HPA073644, HPA073656 Approved Breast cancer:7.05e-8 (unfavourable), Head and neck cancer:2.65e-6 (unfavourable), Cervical cancer:2.69e-5 (unfavourable), Liver cancer:2.74e-4 (unfavourable), Pancreatic cancer:8.34e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 118.2 Expressed in all +GATA1 ERYF1, GATA-1, GF1, NF-E1, NFE1 ENSG00000102145 GATA binding protein 1 X 48786554-48794311 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000232, HPA000233, CAB009195 Enhanced Not detected Tissue enriched 19 bone marrow: 33.2 testis: 1.7 Group enriched 12 HEL: 182.0;HMC-1: 176.5;K-562: 196.6 +MAGT1 DKFZp564K142, IAP, MRX95, OST3B ENSG00000102158 Magnesium transporter 1 X 77826364-77895593 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA049851 Approved Breast cancer:1.30e-4 (unfavourable), Pancreatic cancer:3.55e-4 (unfavourable), Melanoma:8.98e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 137.3 Expressed in all +SMS MRSR, SPMSY, SpS, SRS ENSG00000102172 Spermine synthase X 21940573-21994835 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA029849, HPA029852 Approved Approved Nuclear bodies
Cytosol Liver cancer:7.79e-8 (unfavourable), Renal cancer:7.85e-5 (unfavourable), Head and neck cancer:7.49e-4 (unfavourable) Expressed in all Expressed in all prostate: 202.4 Expressed in all +PHEX HPDR, HPDR1, HYP, HYP1, PEX, XLH ENSG00000102174 Phosphate regulating endopeptidase homolog, X-linked X 22032441-22251310 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Thyroid cancer:2.51e-4 (favourable) Tissue enhanced Tissue enhanced endometrium: 3.5 lung: 2.9 Cell line enhanced PC-3: 2.8;U-87 MG: 6.5;WM-115: 2.8 +UBL4A DXS254E, GDX, GET5, MDY2, TMA24, UBL4 ENSG00000102178 Ubiquitin like 4A X 154483717-154486670 Predicted intracellular proteins Evidence at protein level HPA003617 Approved Supported Nucleoplasm
Cytosol Liver cancer:8.64e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 31.8 Expressed in all +CD99L2 CD99B, MIC2L1 ENSG00000102181 CD99 molecule like 2 X 150766337-150898816 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038782, HPA038783, HPA061400 Enhanced Supported Plasma membrane Pancreatic cancer:2.74e-5 (favourable), Lung cancer:4.96e-4 (favourable), Urothelial cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 143.5 Expressed in all +EEA1 ZFYVE2 ENSG00000102189 Early endosome antigen 1 12 92770637-92929331 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005861, CAB018782, HPA038158, HPA038159 Enhanced Supported Vesicles Expressed in all Expressed in all parathyroid gland: 16.8 Expressed in all +GPR50 H9, Mel1c ENSG00000102195 G protein-coupled receptor 50 X 151176653-151181465 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA049862, HPA054678 Supported Supported Nucleoplasm
Plasma membrane Mixed Not detected placenta: 0.6 Cell line enriched 7 HEK 293: 4.8 +RP2 NM23-H10, NME10, TBCCD2 ENSG00000102218 Retinitis pigmentosa 2 (X-linked recessive) X 46836940-46882358 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000234, HPA000909 Uncertain Approved Nucleoplasm
Nuclear bodies
Plasma membrane Liver cancer:7.97e-4 (unfavourable) Expressed in all Mixed placenta: 35.0 Expressed in all +JADE3 JADE-3, KIAA0215, PHF16 ENSG00000102221 Jade family PHD finger 3 X 46912276-47061242 Predicted intracellular proteins Evidence at protein level HPA006007, HPA064697 Uncertain Approved Nucleus
Nucleoli Expressed in all Mixed testis: 22.6 Cell line enhanced BEWO: 63.4 +CDK16 FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1 ENSG00000102225 Cyclin dependent kinase 16 X 47217860-47229997 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000974, HPA001366, CAB016535 Approved Uncertain Plasma membrane
Microtubules
Cytosol Liver cancer:2.02e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 96.9 Expressed in all +USP11 UHX1 ENSG00000102226 Ubiquitin specific peptidase 11 X 47232690-47248328 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003103, HPA037536 Enhanced Approved Supported Nucleoplasm Renal cancer:4.13e-5 (favourable), Endometrial cancer:2.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 212.7 Expressed in all +PCYT1B CCT-beta, CTB ENSG00000102230 Phosphate cytidylyltransferase 1, choline, beta X 24558087-24672677 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006367 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 21.9;testis: 17.4 fallopian tube,smooth muscle: 4.7 Cell line enhanced AF22: 11.6;CACO-2: 21.4;HEL: 28.7;NTERA-2: 13.3;SCLC-21H: 10.7 +BRS3 BB3, BB3R ENSG00000102239 Bombesin receptor subtype 3 X 136487887-136493780 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 33 epididymis: 30.5 ovary: 0.9 Not detected +HTATSF1 TAT-SF1 ENSG00000102241 HIV-1 Tat specific factor 1 X 136497079-136512346 Predicted intracellular proteins Evidence at protein level HPA000504 Supported Enhanced Nucleoplasm Renal cancer:8.13e-8 (favourable), Cervical cancer:3.78e-4 (favourable) Expressed in all Expressed in all adrenal gland: 125.8 Expressed in all +VGLL1 TDU, TONDU ENSG00000102243 Vestigial like family member 1 X 136532152-136556807 Predicted intracellular proteins Evidence at protein level HPA042403, HPA064616 Supported Supported Nucleus Endometrial cancer:4.54e-4 (unfavourable) Tissue enhanced Tissue enriched 14 placenta: 257.6 urinary bladder: 18.3 Group enriched 11 A-431: 102.6;BEWO: 166.1;CAPAN-2: 56.3;RT4: 243.2;SK-BR-3: 219.4 +CD40LG CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP ENSG00000102245 CD40 ligand X 136648193-136660390 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level HPA045827 Enhanced Mixed Tissue enhanced lymph node: 18.8;tonsil: 14.1 appendix: 10.5 Cell line enriched 65 MOLT-4: 19.2 +TIMP1 CLGI, EPO, TIMP ENSG00000102265 TIMP metallopeptidase inhibitor 1 X 47582313-47586789 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB022360, HPA053417 Approved Approved Golgi apparatus Renal cancer:2.90e-11 (unfavourable), Colorectal cancer:2.09e-4 (unfavourable) Expressed in all Expressed in all appendix: 2036.7 Expressed in all +KLHL4 DKELCHL, KHL4, KIAA1687 ENSG00000102271 Kelch like family member 4 X 87517749-87670050 Predicted intracellular proteins Evidence at protein level HPA029192 Approved Supported Microtubules
Microtubule organizing center Renal cancer:8.08e-5 (unfavourable) Tissue enriched Tissue enhanced adrenal gland: 37.2 testis: 15.6 Cell line enhanced AF22: 15.8;HUVEC TERT2: 28.7;NTERA-2: 25.8;TIME: 31.0 +GABRE ENSG00000102287 Gamma-aminobutyric acid type A receptor epsilon subunit X 151953124-151974680 FDA approved drug targets, Predicted membrane proteins Evidence at transcript level HPA045918 Uncertain Renal cancer:4.05e-11 (unfavourable) Mixed Tissue enhanced adipose tissue: 10.1 heart muscle: 6.4 Cell line enhanced EFO-21: 10.9;HeLa: 3.5;SiHa: 5.9 +PCDH11X PCDH-X, PCDH11, PCDHX, PPP1R119 ENSG00000102290 Protocadherin 11 X-linked X 91779261-92623230 Predicted membrane proteins Evidence at transcript level HPA000432 Approved Not detected Tissue enhanced cerebral cortex: 4.6;ovary: 8.9;parathyroid gland: 4.9 cervix, uterine: 1.5 Cell line enhanced AF22: 1.4;AN3-CA: 2.1 +FGD1 FGDY, ZFYVE3 ENSG00000102302 FYVE, RhoGEF and PH domain containing 1 X 54445454-54496166 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000911 Uncertain Approved Plasma membrane
Cytosol Endometrial cancer:2.10e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 9.5 Mixed +PIN4 EPVH, PAR14, PAR17 ENSG00000102309 Peptidylprolyl cis/trans isomerase, NIMA-interacting 4 X 72181353-72302926 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054483, HPA064504 Approved Supported Nucleus
Nucleoli Testis cancer:2.58e-4 (favourable), Urothelial cancer:2.66e-4 (favourable), Lung cancer:6.37e-4 (favourable) Expressed in all Expressed in all epididymis: 24.3 Expressed in all +PORCN DHOF, MG61, por, PORC, PPN ENSG00000102312 Porcupine homolog (Drosophila) X 48508962-48520814 Disease related genes, Predicted membrane proteins Evidence at protein level HPA049215, HPA058413 Enhanced Approved Vesicles Expressed in all Mixed adrenal gland: 31.4 Cell line enhanced HBEC3-KT: 126.7 +ITIH6 ITIH5L, UNQ6369 ENSG00000102313 Inter-alpha-trypsin inhibitor heavy chain family member 6 X 54748899-54798240 Predicted secreted proteins Evidence at protein level HPA000506 Uncertain Tissue enriched Not detected prostate: 0.6 Cell line enriched 24 WM-115: 50.0 +MAGED2 11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386 ENSG00000102316 MAGE family member D2 X 54807599-54816012 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031572, HPA031573 Supported Enhanced Nucleus
Nucleoli
Cytosol Pancreatic cancer:2.82e-4 (favourable), Ovarian cancer:2.88e-4 (favourable), Stomach cancer:9.43e-4 (unfavourable) Expressed in all Expressed in all prostate: 325.8 Expressed in all +RBM3 IS1-RNPL ENSG00000102317 RNA binding motif (RNP1, RRM) protein 3 X 48574449-48579066 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003624, CAB062559 Enhanced Enhanced Nucleoplasm Colorectal cancer:3.07e-7 (favourable) Expressed in all Expressed in all breast: 237.2 Expressed in all +KLF8 BKLF3, DXS741, ZNF741 ENSG00000102349 Kruppel like factor 8 X 56232421-56287889 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071740 Supported Nucleoplasm Head and neck cancer:3.32e-4 (favourable) Mixed Tissue enhanced skin: 33.8 esophagus: 16.9 Cell line enhanced hTCEpi: 9.9;RT4: 9.7;SK-BR-3: 7.9;T-47d: 18.2 +SRPX2 SRPUL ENSG00000102359 Sushi repeat containing protein, X-linked 2 X 100644166-100675788 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038786 Uncertain Uncertain Microtubules Renal cancer:0.00e+0 (unfavourable) Expressed in all Mixed adipose tissue: 18.8 Cell line enhanced ASC diff: 191.6;ASC TERT1: 83.0;HSkMC: 77.9;HUVEC TERT2: 65.3 +SYTL4 ENSG00000102362 Synaptotagmin like 4 X 100674491-100732123 Predicted intracellular proteins Evidence at protein level HPA001475, HPA001589 Approved Approved Nucleoplasm
Microtubule organizing center
Cytosol Renal cancer:2.09e-4 (unfavourable) Expressed in all Tissue enhanced endometrium: 71.5;ovary: 83.7 smooth muscle: 49.0 Cell line enhanced HAP1: 30.4;HMC-1: 52.7;RT4: 32.5;TIME: 28.4 +ZDHHC15 FLJ31812, MRX91 ENSG00000102383 Zinc finger DHHC-type containing 15 X 75368427-75523502 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at transcript level HPA003618 Uncertain Approved Nuclear speckles
Cytosol Tissue enhanced Mixed cerebral cortex: 4.8 Cell line enhanced HEL: 2.8;MOLT-4: 1.9;NTERA-2: 2.0;RH-30: 3.0;SH-SY5Y: 2.7 +CENPI CENP-I, FSHPRH1, LRPR1, Mis6 ENSG00000102384 Centromere protein I X 101098218-101163681 Predicted intracellular proteins Evidence at protein level HPA061297 Supported Nuclear bodies
Cytosol Mixed Mixed lymph node: 6.6 Mixed +DRP2 ENSG00000102385 Dystrophin related protein 2 X 101219769-101264497 Predicted intracellular proteins Evidence at protein level HPA002949 Approved Nuclear speckles
Plasma membrane Tissue enhanced Tissue enriched 6 cerebral cortex: 12.3 prostate: 2.2 Cell line enhanced RH-30: 10.4;TIME: 15.0;U-87 MG: 4.3 +TAF7L CT40, TAF2Q ENSG00000102387 TATA-box binding protein associated factor 7 like X 101268253-101293057 Predicted intracellular proteins Evidence at protein level HPA001879 Approved Approved Nucleoplasm Cervical cancer:8.71e-4 (favourable) Tissue enhanced Tissue enriched 14 testis: 62.6 parathyroid gland: 4.6 Cell line enriched 23 SiHa: 60.1 +PBDC1 CXorf26, MGC874 ENSG00000102390 Polysaccharide biosynthesis domain containing 1 X 76172936-76178204 Predicted intracellular proteins Evidence at protein level HPA003155 Uncertain Approved Nucleus
Nucleoli
Cytosol Thyroid cancer:8.57e-4 (favourable) Expressed in all Expressed in all prostate: 39.7 Mixed +GLA GALA ENSG00000102393 Galactosidase alpha X 101397803-101407925 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA000237, HPA000966 Enhanced Liver cancer:5.62e-5 (unfavourable), Stomach cancer:6.16e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 59.2 Expressed in all +ARMCX3 ALEX3, GASP6 ENSG00000102401 Armadillo repeat containing, X-linked 3 X 101622797-101627843 Predicted membrane proteins Evidence at protein level HPA000325, HPA000967, HPA001530 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:1.55e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 167.6 Mixed +BEX4 BEXL1, FLJ10097 ENSG00000102409 Brain expressed X-linked 4 X 103215092-103217246 Predicted intracellular proteins Evidence at transcript level HPA045105, HPA051935 Uncertain Approved Nucleus
Cytosol Renal cancer:2.54e-14 (favourable), Pancreatic cancer:9.41e-4 (favourable) Expressed in all Expressed in all epididymis: 323.6 Cell line enhanced HMC-1: 164.0;K-562: 205.1 +RUBCNL C13orf18, FLJ21562, KIAA0226L ENSG00000102445 RUN and cysteine rich domain containing beclin 1 interacting protein like 13 46342000-46438190 Predicted intracellular proteins Evidence at protein level HPA026614 Approved Supported Cytosol Endometrial cancer:3.76e-5 (favourable) Tissue enriched Mixed lymph node: 35.0 Cell line enhanced Daudi: 99.1;REH: 36.6;U-698: 157.0 +NALCN bA430M15.1, CanIon, VGCNL1 ENSG00000102452 Sodium leak channel, non-selective 13 101053776-101416492 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA031889, HPA031890, HPA031958 Approved Mixed Tissue enhanced cerebral cortex: 28.1 adrenal gland: 6.0 Cell line enhanced HaCaT: 12.6;HHSteC: 12.3;TIME: 15.4;U-87 MG: 11.1 +FGF14 FHF4, SCA27 ENSG00000102466 Fibroblast growth factor 14 13 101710804-102402457 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA049828 Approved Nucleoli fibrillar center Tissue enhanced Tissue enhanced cerebral cortex: 14.8;cervix, uterine: 22.9;fallopian tube: 17.2 testis: 4.3 Group enriched 7 SCLC-21H: 5.4;SH-SY5Y: 20.7;U-87 MG: 4.1 +HTR2A 5-HT2A, HTR2 ENSG00000102468 5-hydroxytryptamine receptor 2A 13 46831550-46897076 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA014011 Enhanced Not detected Tissue enriched 8 cerebral cortex: 32.2 smooth muscle: 3.9 Cell line enhanced ASC diff: 1.3;ASC TERT1: 3.2;BEWO: 1.4;HEL: 1.3;U-138 MG: 2.3;U-2 OS: 1.6 +NDFIP2 KIAA1165, N4wbp5a ENSG00000102471 Nedd4 family interacting protein 2 13 79481124-79556075 Predicted membrane proteins Evidence at protein level HPA009160 Uncertain Enhanced Vesicles Renal cancer:4.18e-5 (favourable), Head and neck cancer:5.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 96.0 Mixed +TNFSF13B BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20 ENSG00000102524 Tumor necrosis factor superfamily member 13b 13 108251240-108308484 Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009188 Enhanced Renal cancer:2.53e-11 (unfavourable) Expressed in all Mixed appendix: 35.3 Cell line enriched 9 U-937: 130.0 +FNDC3A bA203I16.5, FNDC3, KIAA0970 ENSG00000102531 Fibronectin type III domain containing 3A 13 48975912-49209779 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008927, HPA012825 Approved Approved Endoplasmic reticulum Renal cancer:4.25e-4 (favourable) Expressed in all Expressed in all thyroid gland: 85.7 Expressed in all +MLNR GPR38 ENSG00000102539 Motilin receptor 13 49220338-49222377 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enhanced thyroid gland: 2.8 bone marrow: 0.8 Cell line enhanced NTERA-2: 1.3;THP-1: 2.7 +CDADC1 NYD-SP15 ENSG00000102543 Cytidine and dCMP deaminase domain containing 1 13 49247925-49293485 Predicted intracellular proteins Evidence at transcript level HPA047615, HPA058314 Uncertain Approved Nucleoplasm Renal cancer:1.19e-5 (favourable), Lung cancer:6.03e-4 (favourable) Expressed in all Mixed thyroid gland: 15.7 Mixed +CAB39L bA103J18.3, FLJ12577, MO2L ENSG00000102547 Calcium binding protein 39 like 13 49308650-49444126 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003686, HPA045954 Uncertain Approved Vesicles Renal cancer:1.94e-13 (favourable), Ovarian cancer:2.28e-4 (unfavourable), Prostate cancer:7.91e-4 (favourable) Expressed in all Expressed in all prostate: 66.2 Cell line enhanced CACO-2: 32.9;RT4: 33.1 +KLF5 BTEB2, CKLF, IKLF ENSG00000102554 Kruppel like factor 5 13 73054976-73077542 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA040398 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Pancreatic cancer:2.55e-4 (unfavourable) Expressed in all Tissue enhanced skin: 279.6 esophagus: 216.2 Cell line enhanced HaCaT: 113.4;hTCEpi: 113.2;RT4: 108.4;SiHa: 121.1 +STK24 MST-3, MST3, MST3B, STE20, STK3 ENSG00000102572 Serine/threonine kinase 24 13 98445185-98577940 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026435, HPA026502 Enhanced Supported Nucleoli
Cytosol Lung cancer:6.23e-6 (unfavourable), Renal cancer:6.91e-5 (favourable), Pancreatic cancer:5.81e-4 (unfavourable) Expressed in all Expressed in all esophagus: 169.5 Expressed in all +ACP5 HPAP, TRAP ENSG00000102575 Acid phosphatase 5, tartrate resistant 19 11574660-11579008 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002584, HPA057655, HPA059463 Enhanced Approved Cytosol Expressed in all Tissue enhanced lung: 254.0 lymph node: 86.3 Cell line enhanced BEWO: 36.2;SK-MEL-30: 85.3;U-138 MG: 97.5 +DNAJC3 ERdj6, HP58, P58, P58IPK, PRKRI ENSG00000102580 DnaJ heat shock protein family (Hsp40) member C3 13 95677139-95794989 Disease related genes, Predicted secreted proteins Evidence at protein level HPA039336, HPA041326 Uncertain Approved Endoplasmic reticulum Endometrial cancer:3.47e-5 (favourable) Expressed in all Expressed in all thyroid gland: 88.4 Mixed +UGGT2 FLJ10873, FLJ11485, HUGT2, MGC117360, MGC150689, MGC87276, UGCGL2 ENSG00000102595 UDP-glucose glycoprotein glucosyltransferase 2 13 95801580-96053482 Predicted secreted proteins Evidence at protein level HPA047955 Uncertain Lung cancer:5.47e-4 (unfavourable), Liver cancer:9.99e-4 (unfavourable) Expressed in all Mixed testis: 22.7 Mixed +ARHGEF7 BETA-PIX, COOL1, DKFZp686C12170, DKFZp761K1021, KIAA0142, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB ENSG00000102606 Rho guanine nucleotide exchange factor 7 13 111114559-111305737 Predicted intracellular proteins Evidence at protein level HPA004744 Approved Glioma:7.29e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 96.8 Expressed in all +FGF9 ENSG00000102678 Fibroblast growth factor 9 13 21671383-21704498 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA067007 Enhanced Renal cancer:1.70e-6 (favourable) Tissue enhanced Tissue enhanced kidney: 12.1 adrenal gland: 4.7 Cell line enhanced RPTEC TERT1: 2.5;SCLC-21H: 8.0 +SGCG A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE ENSG00000102683 Sarcoglycan gamma 13 23180952-23325165 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA007476, HPA011922 Enhanced Supported Nucleoplasm Mixed Tissue enhanced heart muscle: 74.9;skeletal muscle: 54.0 adipose tissue: 14.5 Cell line enriched 5 fHDF/TERT166: 50.4 +PARP4 ADPRTL1, p193, VAULT3, VPARP, VWA5C ENSG00000102699 Poly(ADP-ribose) polymerase family member 4 13 24420926-24512810 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011739 Approved Supported Cytosol Renal cancer:1.21e-5 (favourable) Expressed in all Expressed in all gallbladder: 46.0 Expressed in all +SUPT20H bA421P11.4, C13orf19, FAM48A, P38IP, SPT20 ENSG00000102710 SPT20 homolog, SAGA complex component 13 37009312-37059713 Predicted intracellular proteins Evidence at protein level HPA038906, HPA038907 Uncertain Supported Nucleoli fibrillar center Expressed in all Expressed in all testis: 100.1 Expressed in all +MRPS31 IMOGN38 ENSG00000102738 Mitochondrial ribosomal protein S31 13 40729135-40771173 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA039083, HPA046344 Uncertain Supported Nucleoli
Mitochondria Expressed in all Expressed in all testis,thyroid gland: 33.6 Expressed in all +SLC25A15 D13S327, HHH, ORC1, ORNT1 ENSG00000102743 Solute carrier family 25 member 15 13 40789412-40810111 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA042146 Approved Renal cancer:1.74e-4 (favourable), Liver cancer:2.16e-4 (favourable), Urothelial cancer:5.46e-4 (unfavourable) Expressed in all Expressed in all liver: 49.6 Expressed in all +KPNA3 hSRP1, IPOA4, SRP1gamma, SRP4 ENSG00000102753 Karyopherin subunit alpha 3 13 49699307-49792921 Predicted intracellular proteins, Transporters Evidence at protein level HPA046852 Approved Approved Nucleoplasm
Cytosol Glioma:1.48e-4 (favourable), Cervical cancer:2.80e-4 (unfavourable), Renal cancer:3.81e-4 (unfavourable) Expressed in all Expressed in all testis: 49.8 Expressed in all +FLT1 FLT, VEGFR1 ENSG00000102755 Fms related tyrosine kinase 1 13 28300344-28495145 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA011740, HPA014290, CAB068189, CAB068190 Enhanced Supported Plasma membrane
Actin filaments Renal cancer:2.19e-4 (unfavourable) Expressed in all Tissue enriched 8 placenta: 622.5 thyroid gland: 81.9 Cell line enhanced BJ: 61.1;HMC-1: 308.1;WM-115: 126.2 +RGCC bA157L14.2, C13orf15, RGC-32, RGC32 ENSG00000102760 Regulator of cell cycle 13 41457559-41470882 Predicted secreted proteins Evidence at protein level HPA035638, HPA063701 Approved Supported Nucleus
Nucleoli Colorectal cancer:5.60e-4 (unfavourable) Expressed in all Expressed in all lung: 409.0 Cell line enhanced BJ hTERT+: 255.6;Daudi: 75.1;U-698: 75.7 +VWA8 KIAA0564 ENSG00000102763 Von Willebrand factor A domain containing 8 13 41566837-41961120 Predicted intracellular proteins Evidence at protein level HPA039075, HPA045478 Uncertain Approved Vesicles
Lipid droplets Renal cancer:6.38e-14 (favourable), Liver cancer:8.56e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.8 Mixed +DGKH DGKeta ENSG00000102780 Diacylglycerol kinase eta 13 42040036-42256578 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039533, HPA040355 Uncertain Mixed Mixed epididymis: 8.4 Mixed +KATNAL1 MGC2599 ENSG00000102781 Katanin catalytic subunit A1 like 1 13 30202630-30307484 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046205 Uncertain Nucleoplasm
Cytosol Expressed in all Tissue enhanced testis: 37.7 smooth muscle: 21.9 Mixed +INTS6 DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2 ENSG00000102786 Integrator complex subunit 6 13 51354077-51454264 Predicted intracellular proteins Evidence at protein level HPA001552, HPA001846 Supported Enhanced Nucleoplasm
Actin filaments Expressed in all Expressed in all testis: 103.4 Expressed in all +ACOD1 CAD, IRG1 ENSG00000102794 Aconitate decarboxylase 1 13 76948497-76958642 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040143 Uncertain Not detected Tissue enriched 5 appendix: 1.9 lung: 0.3 Not detected +DHRS12 FLJ13639, SDR40C1 ENSG00000102796 Dehydrogenase/reductase 12 13 51767993-51804157 Predicted intracellular proteins Evidence at protein level CAB034238, HPA057028, HPA058315 Uncertain Supported Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:2.22e-16 (favourable), Breast cancer:1.41e-4 (favourable) Expressed in all Expressed in all epididymis: 22.0 Mixed +MEDAG AWMS3, C13orf33, FLJ14834, MEDA-4 ENSG00000102802 Mesenteric estrogen dependent adipogenesis 13 30906191-30925572 Predicted intracellular proteins Evidence at transcript level Renal cancer:3.29e-5 (unfavourable) Mixed Tissue enhanced adipose tissue: 153.5 smooth muscle: 32.2 Cell line enhanced ASC diff: 206.4;ASC TERT1: 58.9;U-2197: 157.4 +TSC22D1 MGC17597, TGFB1I4, TSC22 ENSG00000102804 TSC22 domain family member 1 13 44432143-44577147 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA077414 Approved Nucleoplasm
Nuclear bodies Renal cancer:4.54e-4 (favourable), Ovarian cancer:7.97e-4 (unfavourable) Expressed in all Expressed in all prostate: 269.2 Cell line enhanced HEL: 221.4 +CLN5 ENSG00000102805 Ceroid-lipofuscinosis, neuronal 5 13 76990660-77019143 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA041788 Approved Renal cancer:1.52e-9 (favourable) Expressed in all Expressed in all thyroid gland: 127.1 Expressed in all +OLFM4 GC1, GW112, OlfD ENSG00000102837 Olfactomedin 4 13 53028759-53052057 Predicted secreted proteins Evidence at protein level HPA077718 Enhanced Breast cancer:8.77e-4 (favourable) Group enriched Tissue enhanced duodenum: 1193.9;rectum: 611.5;small intestine: 1437.8 colon: 445.0 Cell line enhanced BEWO: 5.1;BJ hTERT+: 15.0;HaCaT: 22.9 +MSLN CAK1, MPF ENSG00000102854 Mesothelin 16 760762-768865 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002216, HPA017172 Enhanced Approved Nucleoplasm
Vesicles Renal cancer:5.91e-4 (favourable), Pancreatic cancer:6.66e-4 (unfavourable) Tissue enhanced Group enriched 9 fallopian tube: 445.8;lung: 105.4 epididymis: 29.1 Cell line enhanced CAPAN-2: 448.3;EFO-21: 72.6;HeLa: 104.4;hTCEpi: 80.2 +MGRN1 KIAA0544, RNF156 ENSG00000102858 Mahogunin ring finger 1 16 4616493-4690974 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007653 Approved Expressed in all Expressed in all cerebral cortex: 56.4 Expressed in all +ZNF629 KIAA0326, ZNF65 ENSG00000102870 Zinc finger protein 629 16 30778449-30787202 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019550, HPA056051 Uncertain Supported Nucleus
Golgi apparatus Renal cancer:4.57e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 27.8 Mixed +TRADD Hs.89862 ENSG00000102871 TNFRSF1A associated via death domain 16 67154180-67160298 Predicted intracellular proteins Evidence at protein level CAB004602, HPA071341 Enhanced Approved Cytosol Endometrial cancer:1.40e-4 (favourable) Expressed in all Mixed spleen: 17.6 Mixed +HSF4 CTM ENSG00000102878 Heat shock transcription factor 4 16 67164681-67169945 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048584 Supported Nuclear speckles Renal cancer:2.19e-6 (unfavourable), Colorectal cancer:8.24e-5 (unfavourable) Expressed in all Mixed adrenal gland: 14.8 Cell line enhanced T-47d: 12.3;U-266/70: 18.1 +CORO1A coronin-1, HCORO1, p57 ENSG00000102879 Coronin 1A 16 30182827-30189076 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB046473, HPA051132 Enhanced Approved Cytosol Renal cancer:5.74e-7 (unfavourable), Head and neck cancer:4.42e-4 (favourable), Endometrial cancer:6.91e-4 (favourable) Expressed in all Expressed in all lymph node: 593.1 Cell line enhanced Daudi: 596.0;HMC-1: 850.4;RPMI-8226: 612.4;U-937: 575.5 +MAPK3 ERK1, p44erk1, p44mapk, PRKM3 ENSG00000102882 Mitogen-activated protein kinase 3 16 30114105-30123506 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002683, HPA003995, HPA005700, HPA030069 Approved Approved Nucleoplasm Liver cancer:1.11e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 133.7 Expressed in all +GDPD3 MGC4171 ENSG00000102886 Glycerophosphodiester phosphodiesterase domain containing 3 16 30104810-30113856 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041148, HPA041470 Uncertain Approved Nucleoplasm
Cytokinetic bridge
Cytosol Renal cancer:5.89e-9 (unfavourable) Expressed in all Mixed esophagus: 23.1 Cell line enhanced MCF7: 24.3;SK-BR-3: 81.3 +ELMO3 CED-12, CED12, ELMO-3, FLJ13824 ENSG00000102890 Engulfment and cell motility 3 16 67199111-67204029 Predicted intracellular proteins Evidence at protein level HPA021484 Approved Approved Plasma membrane
Cell Junctions Renal cancer:2.77e-5 (favourable) Expressed in all Mixed skin: 39.3 Cell line enhanced BEWO: 31.7;CAPAN-2: 43.1;HaCaT: 41.1;T-47d: 42.8 +MT4 MTIV ENSG00000102891 Metallothionein 4 16 56565049-56568957 Predicted intracellular proteins Evidence at transcript level Group enriched Tissue enriched 5 skin: 13.7 testis: 2.6 Not detected +PHKB ENSG00000102893 Phosphorylase kinase regulatory subunit beta 16 47461123-47701523 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA073380 Approved Golgi apparatus Renal cancer:3.89e-9 (favourable), Thyroid cancer:3.24e-4 (unfavourable), Colorectal cancer:3.69e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 99.3 Expressed in all +LYRM1 A211C6.1 ENSG00000102897 LYR motif containing 1 16 20899868-20925006 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA059840 Supported Nucleoplasm
Midbody Endometrial cancer:7.48e-7 (favourable), Renal cancer:4.80e-4 (unfavourable), Urothelial cancer:9.50e-4 (favourable) Expressed in all Expressed in all testis: 70.4 Expressed in all +NUTF2 NTF2, PP15 ENSG00000102898 Nuclear transport factor 2 16 67846732-67872567 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040915, HPA040956 Enhanced Approved Microtubules Head and neck cancer:1.15e-4 (unfavourable), Renal cancer:2.58e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 83.7 Expressed in all +NUP93 KIAA0095 ENSG00000102900 Nucleoporin 93 16 56730105-56850286 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA017937 Uncertain Liver cancer:1.72e-6 (unfavourable) Expressed in all Expressed in all testis: 74.6 Expressed in all +CENPT C16orf56, CENP-T, FLJ13111 ENSG00000102901 Centromere protein T 16 67828157-67847811 Predicted intracellular proteins Evidence at protein level HPA041220, HPA058036 Approved Enhanced Nuclear bodies Renal cancer:1.57e-7 (unfavourable), Pancreatic cancer:2.96e-4 (favourable) Expressed in all Expressed in all skin: 15.9 Mixed +TSNAXIP1 TXI1 ENSG00000102904 Translin associated factor X interacting protein 1 16 67806765-67832148 Predicted intracellular proteins Evidence at protein level HPA053516 Approved Nucleus
Cytosol Endometrial cancer:2.22e-4 (favourable) Mixed Group enriched 10 fallopian tube: 15.6;testis: 39.9 parathyroid gland: 2.7 Cell line enhanced AN3-CA: 2.8 +NFAT5 KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP ENSG00000102908 Nuclear factor of activated T-cells 5 16 69565094-69704666 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057304, HPA069711 Approved Supported Nucleus
Cytosol Renal cancer:1.08e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 38.4 Expressed in all +LONP2 LONP, LONPL, MGC4840 ENSG00000102910 Lon peptidase 2, peroxisomal 16 48244296-48363122 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008862 Uncertain Renal cancer:6.71e-7 (favourable), Cervical cancer:4.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 81.8 Expressed in all +N4BP1 ENSG00000102921 NEDD4 binding protein 1 16 48538726-48620148 Predicted intracellular proteins Evidence at protein level HPA040849, HPA041080 Approved Approved Nucleoli fibrillar center Renal cancer:9.03e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 22.1 Expressed in all +CBLN1 ENSG00000102924 Cerebellin 1 precursor 16 49277917-49281831 Predicted secreted proteins Evidence at protein level Thyroid cancer:7.10e-4 (favourable) Tissue enhanced Tissue enhanced testis: 32.4 adipose tissue: 12.3 Group enriched 30 NTERA-2: 40.0;SCLC-21H: 148.4 +ARL2BP BART, BART1, RP66 ENSG00000102931 ADP ribosylation factor like GTPase 2 binding protein 16 57245098-57253635 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043066, HPA048440 Approved Lung cancer:9.06e-5 (unfavourable) Expressed in all Expressed in all testis: 96.1 Expressed in all +PLLP PMLP, TM4SF11 ENSG00000102934 Plasmolipin 16 57248547-57284687 Predicted membrane proteins Evidence at protein level HPA041862 Enhanced Renal cancer:6.21e-9 (favourable), Endometrial cancer:2.80e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 118.0 Cell line enhanced EFO-21: 25.9;Hep G2: 54.1;RPTEC TERT1: 24.7 +ZNF423 Ebfaz, JBTS19, KIAA0760, NPHP14, OAZ, Roaz, Zfp104 ENSG00000102935 Zinc finger protein 423 16 49487524-49857919 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015258, HPA065820 Uncertain Enhanced Nucleus Mixed Mixed fallopian tube: 15.4 Cell line enhanced AF22: 53.5;NTERA-2: 27.7;REH: 22.3;SCLC-21H: 34.3;SH-SY5Y: 92.6 +CCL22 A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1 ENSG00000102962 C-C motif chemokine ligand 22 16 57358772-57366190 Predicted secreted proteins Evidence at protein level Endometrial cancer:2.23e-6 (favourable), Head and neck cancer:9.17e-5 (favourable), Colorectal cancer:2.98e-4 (favourable) Mixed Tissue enhanced appendix: 18.6;tonsil: 13.5 skin: 7.9 Cell line enriched 21 HDLM-2: 45.9 +DHODH ENSG00000102967 Dihydroorotate dehydrogenase (quinone) 16 72008588-72027664 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010123, HPA011942 Approved Supported Nucleoplasm
Mitochondria Expressed in all Mixed liver: 21.4 Expressed in all +CCL17 ABCD-2, SCYA17, TARC ENSG00000102970 C-C motif chemokine ligand 17 16 57404767-57416062 Predicted secreted proteins Evidence at protein level CAB002583 Approved Cervical cancer:1.91e-5 (favourable), Urothelial cancer:5.80e-4 (favourable) Mixed Tissue enhanced appendix: 11.1;lymph node: 9.9 tonsil: 5.4 Cell line enriched 725 HDLM-2: 2231.6 +CTCF ENSG00000102974 CCCTC-binding factor 16 67562407-67639183 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004122, CAB062550, CAB068181, CAB068182 Supported Supported Nucleoplasm Renal cancer:4.06e-4 (favourable), Liver cancer:4.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 58.6 Expressed in all +ACD Pip1, Ptop, Tint1, Tpp1 ENSG00000102977 ACD, shelterin complex subunit and telomerase recruitment factor 16 67657512-67660815 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049411, HPA057660 Approved Enhanced Nuclear bodies Liver cancer:2.42e-6 (unfavourable) Expressed in all Mixed testis: 18.4 Expressed in all +POLR2C RPB3 ENSG00000102978 RNA polymerase II subunit C 16 57462387-57472010 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA040919, HPA041826 Enhanced Supported Nucleoplasm
Microtubules
Cytosol Renal cancer:3.03e-6 (favourable), Head and neck cancer:1.48e-4 (unfavourable) Expressed in all Expressed in all epididymis: 68.2 Expressed in all +PARD6A PAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40 ENSG00000102981 Par-6 family cell polarity regulator alpha 16 67660946-67662778 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009733, HPA041551 Approved Supported Cell Junctions
Actin filaments
Cytosol Renal cancer:3.08e-7 (favourable), Breast cancer:5.40e-4 (favourable) Expressed in all Tissue enhanced testis: 20.2 cerebral cortex: 12.1 Cell line enhanced REH: 24.9;SCLC-21H: 25.2 +ZNF821 ENSG00000102984 Zinc finger protein 821 16 71859680-71895336 Predicted intracellular proteins Evidence at protein level HPA036372, HPA042742 Enhanced Supported Nucleoplasm
Nuclear speckles Renal cancer:6.32e-10 (favourable), Pancreatic cancer:4.27e-5 (favourable), Glioma:1.55e-4 (favourable) Expressed in all Tissue enhanced testis: 33.2 cerebral cortex: 13.7 Cell line enhanced SCLC-21H: 15.5 +MMP15 MT2-MMP, MTMMP2, SMCP-2 ENSG00000102996 Matrix metallopeptidase 15 16 58025566-58046901 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002611, HPA040390 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:8.54e-8 (favourable), Urothelial cancer:3.08e-4 (favourable) Expressed in all Tissue enhanced thyroid gland: 70.1 placenta: 39.3 Cell line enhanced BEWO: 86.0;WM-115: 73.7 +USB1 C16orf57, FLJ13154, HVSL1, Mpn1 ENSG00000103005 U6 snRNA biogenesis phosphodiesterase 1 16 57999546-58021618 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041791, HPA059854 Approved Supported Nucleus Liver cancer:6.69e-7 (unfavourable), Renal cancer:2.02e-4 (unfavourable) Expressed in all Expressed in all appendix: 37.4 Expressed in all +CYB5B CYB5-M ENSG00000103018 Cytochrome b5 type B 16 69424525-69466266 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007893 Approved Approved Endoplasmic reticulum
Microtubule organizing center
Cytosol Renal cancer:6.38e-5 (favourable), Head and neck cancer:2.51e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 398.0 Expressed in all +CCDC113 DKFZp434N1418, HSPC065 ENSG00000103021 Coiled-coil domain containing 113 16 58231157-58283836 Predicted intracellular proteins Evidence at protein level HPA040759, HPA040869 Uncertain Approved Nucleoplasm
Cytosol Endometrial cancer:7.01e-4 (favourable), Colorectal cancer:8.65e-4 (favourable) Mixed Tissue enhanced fallopian tube: 50.1;testis: 32.8 parathyroid gland: 16.3 Cell line enhanced SiHa: 30.0 +PRSS54 CT67, FLJ25339, KLKBL4 ENSG00000103023 Protease, serine 54 16 58279997-58295047 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041549 Enhanced Not detected Tissue enriched 461 testis: 63.1 cerebral cortex,urinary bladder: 0.1 Not detected +NME3 DR-nm23, NDPKC, NM23-H3 ENSG00000103024 NME/NM23 nucleoside diphosphate kinase 3 16 1770286-1771730 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041113, HPA052733 Approved Approved Nucleoplasm
Cytosol Breast cancer:6.81e-5 (favourable) Expressed in all Expressed in all adrenal gland: 36.1 Cell line enhanced HEK 293: 64.8 +NDRG4 KIAA1180, SMAP-8 ENSG00000103034 NDRG family member 4 16 58462846-58513628 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015313, HPA017587 Enhanced Uncertain Nucleus
Cytosol Tissue enriched Tissue enhanced adrenal gland: 146.6;cerebral cortex: 420.0;heart muscle: 150.6 testis: 72.0 Cell line enhanced EFO-21: 30.7;SCLC-21H: 58.1 +PSMD7 MOV34, P40, Rpn8, S12 ENSG00000103035 Proteasome 26S subunit, non-ATPase 7 16 74296775-74306288 Enzymes, Predicted intracellular proteins Evidence at protein level CAB019379, HPA049824, HPA056069 Enhanced Enhanced Nucleoplasm Liver cancer:7.71e-6 (unfavourable), Head and neck cancer:6.64e-5 (unfavourable) Expressed in all Expressed in all prostate: 107.1 Expressed in all +SETD6 FLJ21148 ENSG00000103037 SET domain containing 6 16 58515479-58521181 Predicted intracellular proteins Evidence at protein level HPA041481, HPA053546 Uncertain Supported Nucleus
Cytosol Prostate cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 19.8 Mixed +SLC38A7 FLJ10815 ENSG00000103042 Solute carrier family 38 member 7 16 58665109-58685104 Predicted membrane proteins, Transporters Evidence at protein level HPA041777 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:2.87e-4 (favourable), Endometrial cancer:6.87e-4 (favourable) Expressed in all Mixed testis: 34.7 Expressed in all +VAC14 ArPIKfyve, FLJ10305, TAX1BP2 ENSG00000103043 Vac14, PIKFYVE complex component 16 70687439-70801161 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027766 Approved Approved Vesicles
Cytosol Renal cancer:1.56e-6 (favourable), Cervical cancer:8.33e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 31.6 Expressed in all +HAS3 ENSG00000103044 Hyaluronan synthase 3 16 69105564-69118719 Enzymes, Predicted membrane proteins Evidence at protein level HPA031554, CAB033850 Supported Approved Microtubules Pancreatic cancer:5.36e-4 (unfavourable) Group enriched Tissue enhanced lung: 29.9;urinary bladder: 36.4 stomach: 11.8 Cell line enhanced HaCaT: 46.5;PC-3: 257.9;RT4: 89.2 +TANGO6 FLJ12688, KIAA1746, TMCO7 ENSG00000103047 Transport and golgi organization 6 homolog 16 68843604-69085180 Predicted membrane proteins Evidence at protein level HPA041312 Approved Approved Golgi apparatus
Cytosol Renal cancer:3.20e-4 (favourable) Expressed in all Mixed parathyroid gland: 15.2 Expressed in all +COG4 COD1, DKFZP586E1519 ENSG00000103051 Component of oligomeric golgi complex 4 16 70480568-70523565 Predicted intracellular proteins Evidence at protein level HPA040924, HPA042539 Approved Approved Golgi apparatus
Vesicles Liver cancer:1.64e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.1 Expressed in all +SMPD3 NSMASE2 ENSG00000103056 Sphingomyelin phosphodiesterase 3 16 68358325-68448688 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB033885, HPA065535, HPA069383 Approved Supported Endoplasmic reticulum Endometrial cancer:3.86e-4 (favourable), Cervical cancer:7.72e-4 (favourable) Mixed Tissue enhanced duodenum: 61.0;small intestine: 62.9 stomach: 22.6 Cell line enhanced HMC-1: 8.5;MOLT-4: 11.7;RPMI-8226: 8.3;SCLC-21H: 15.6 +SLC7A6OS FLJ13291 ENSG00000103061 Solute carrier family 7 member 6 opposite strand 16 68284503-68310946 Predicted intracellular proteins Evidence at protein level HPA041533 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.35e-4 (favourable) Mixed Expressed in all lymph node: 18.9 Expressed in all +SLC7A6 KIAA0245, LAT-2, LAT3, y+LAT-2 ENSG00000103064 Solute carrier family 7 member 6 16 68264516-68301823 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA050713 Uncertain Approved Vesicles
Plasma membrane Urothelial cancer:1.84e-4 (unfavourable) Expressed in all Mixed adipose tissue: 35.7 Expressed in all +PLA2G15 GXVPLA2, LLPL, LYPLA3 ENSG00000103066 Phospholipase A2 group XV 16 68245304-68261062 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA041702, HPA041727 Enhanced Supported Nucleoplasm
Vesicles Expressed in all Expressed in all placenta: 37.5 Expressed in all +ESRP2 FLJ21918, RBM35B ENSG00000103067 Epithelial splicing regulatory protein 2 16 68229111-68238102 Predicted intracellular proteins Evidence at protein level HPA040751, HPA048597, HPA048618 Uncertain Enhanced Nucleoplasm Renal cancer:1.30e-6 (favourable) Mixed Mixed skin: 37.1 Cell line enhanced BEWO: 45.7;MCF7: 74.1;RT4: 40.9;T-47d: 73.0 +FA2H FAAH, FAXDC1, FLJ25287, SPG35 ENSG00000103089 Fatty acid 2-hydroxylase 16 74712955-74774831 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA056614, HPA077840 Approved Uncertain Nuclear membrane Renal cancer:5.01e-6 (favourable), Pancreatic cancer:3.74e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 51.6;stomach: 57.4 gallbladder: 28.6 Cell line enhanced A549: 34.7;CAPAN-2: 18.4;HAP1: 50.4;SK-BR-3: 21.5 +WDR59 FLJ12270 ENSG00000103091 WD repeat domain 59 16 74871367-75000173 Predicted intracellular proteins Evidence at protein level HPA041084, HPA048218 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 44.0 Expressed in all +MON1B HSRG1, KIAA0872, SAND2 ENSG00000103111 MON1 homolog B, secretory trafficking associated 16 77190835-77202405 Predicted intracellular proteins Evidence at protein level HPA046285 Approved Approved Cytosol Renal cancer:9.42e-5 (favourable), Endometrial cancer:6.90e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.2 Expressed in all +CMC2 C16orf61, DC13, MGC45036 ENSG00000103121 C-X9-C motif containing 2 16 80966448-81020270 Predicted intracellular proteins Evidence at protein level HPA006871, CAB026396 Approved Supported Mitochondria Renal cancer:2.64e-5 (favourable) Expressed in all Expressed in all testis: 81.9 Expressed in all +AXIN1 PPP1R49 ENSG00000103126 Axin 1 16 287440-352673 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012987 Approved Supported Nucleoli
Vesicles Liver cancer:3.38e-5 (unfavourable) Expressed in all Expressed in all spleen: 15.5 Expressed in all +HCFC1R1 FLJ20568, HPIP ENSG00000103145 Host cell factor C1 regulator 1 16 3022620-3024286 Predicted intracellular proteins Evidence at protein level HPA059647 Approved Approved Nucleoplasm Expressed in all Expressed in all skeletal muscle: 184.4 Expressed in all +NPRL3 C16orf35, CGTHBA, HS-40, MARE, NPR3, RMD11 ENSG00000103148 NPR3 like, GATOR1 complex subunit 16 84271-138860 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA011741 Uncertain Approved Cytosol Expressed in all Expressed in all parathyroid gland: 27.1 Mixed +MLYCD hMCD, MCD ENSG00000103150 Malonyl-CoA decarboxylase 16 83899126-83927026 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA031625 Enhanced Renal cancer:2.61e-7 (favourable) Expressed in all Mixed heart muscle: 3.2 Mixed +MPG MDG ENSG00000103152 N-methylpurine DNA glycosylase 16 77007-85853 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006531 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:2.82e-5 (favourable) Expressed in all Expressed in all thyroid gland: 49.0 Expressed in all +NECAB2 EFCBP2 ENSG00000103154 N-terminal EF-hand calcium binding protein 2 16 83968632-84002776 Predicted intracellular proteins Evidence at protein level HPA013998, HPA014144, CAB068211 Enhanced Supported Approved Vesicles Renal cancer:1.58e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 46.8 kidney: 10.6 Cell line enhanced AF22: 10.4;SCLC-21H: 47.1;U-87 MG: 13.8 +HSDL1 SDR12C3 ENSG00000103160 Hydroxysteroid dehydrogenase like 1 16 84122146-84145192 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:4.20e-7 (favourable), Liver cancer:3.50e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 45.8 Expressed in all +TAF1C MGC:39976, SL1, TAFI110, TAFI95 ENSG00000103168 TATA-box binding protein associated factor, RNA polymerase I subunit C 16 84177847-84187070 Predicted intracellular proteins Evidence at protein level HPA072229 Supported Nucleus
Nucleoli fibrillar center Renal cancer:8.08e-6 (unfavourable), Pancreatic cancer:1.76e-4 (favourable), Urothelial cancer:3.22e-4 (favourable) Expressed in all Expressed in all gallbladder: 15.5 Expressed in all +NAGPA APAA, UCE ENSG00000103174 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 16 5024844-5034141 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA064055 Approved Renal cancer:2.67e-5 (unfavourable), Liver cancer:4.67e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 9.6 Mixed +WFDC1 PS20 ENSG00000103175 WAP four-disulfide core domain 1 16 84294646-84329851 Predicted secreted proteins Evidence at transcript level HPA031411 Uncertain Mixed Tissue enhanced placenta: 121.8;seminal vesicle: 135.6 prostate: 88.4 Cell line enhanced AN3-CA: 24.0;BJ: 15.1;HEL: 13.6;HeLa: 16.0 +SEC14L5 KIAA0420, PRELID4B ENSG00000103184 SEC14 like lipid binding 5 16 4958317-5019158 Predicted intracellular proteins Evidence at protein level HPA041492, HPA041825 Uncertain Golgi apparatus
Cytosol Mixed Tissue enriched 7 cerebral cortex: 17.1 heart muscle: 2.3 Cell line enhanced SCLC-21H: 3.2;T-47d: 1.7 +COTL1 CLP ENSG00000103187 Coactosin like F-actin binding protein 1 16 84565594-84618077 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008918, CAB062328 Enhanced Renal cancer:5.51e-4 (unfavourable) Expressed in all Expressed in all lymph node: 421.9 Expressed in all +USP10 KIAA0190, UBPO ENSG00000103194 Ubiquitin specific peptidase 10 16 84699978-84779922 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006731, HPA006749 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:1.00e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 63.1 Expressed in all +CRISPLD2 DKFZP434B044, LCRISP2, LGL1 ENSG00000103196 Cysteine rich secretory protein LCCL domain containing 2 16 84819984-84920768 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030054, HPA030055 Approved Approved Nucleus
Nucleoli Renal cancer:1.97e-6 (unfavourable) Expressed in all Expressed in all placenta: 174.3 Cell line enhanced BEWO: 66.9;HHSteC: 135.7;HSkMC: 49.5 +TSC2 LAM, PPP1R160, TSC4, tuberin ENSG00000103197 Tuberous sclerosis 2 16 2047465-2088720 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002225, HPA030409, HPA049679 Approved Enhanced Cytosol Pancreatic cancer:5.06e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 36.7 Expressed in all +ZNF500 KIAA0557, ZKSCAN18, ZSCAN50 ENSG00000103199 Zinc finger protein 500 16 4748239-4767624 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035498, HPA057963 Supported Enhanced Nucleoplasm
Cytosol Stomach cancer:3.41e-4 (favourable) Expressed in all Mixed spleen: 5.6 Expressed in all +NME4 NDPKD, nm23-H4, NM23H4 ENSG00000103202 NME/NM23 nucleoside diphosphate kinase 4 16 396725-410367 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB045997, HPA072588 Approved Supported Mitochondria Renal cancer:1.61e-7 (unfavourable), Cervical cancer:6.53e-4 (unfavourable) Expressed in all Expressed in all prostate: 167.2 Mixed +ABCC1 GS-X, MRP, MRP1 ENSG00000103222 ATP binding cassette subfamily C member 1 16 15949577-16143074 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA002380 Uncertain Supported Plasma membrane Renal cancer:1.55e-6 (unfavourable), Liver cancer:5.42e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 18.6 Cell line enhanced EFO-21: 84.1 +NOMO3 ENSG00000103226 NODAL modulator 3 16 16232495-16294814 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA046697, HPA061174 Approved Mixed Mixed skin: 1.9 Mixed +LMF1 C16orf26, FLJ12681, FLJ22302, JFP11, TMEM112, TMEM112A ENSG00000103227 Lipase maturation factor 1 16 853634-981318 Disease related genes, Predicted membrane proteins Evidence at protein level Renal cancer:7.95e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 23.2 Mixed +FOXF1 FKHL5, FREAC1 ENSG00000103241 Forkhead box F1 16 86510527-86515418 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028886 Approved Nucleoplasm Mixed Mixed placenta: 33.0 Cell line enhanced BJ: 10.8;BJ hTERT+: 22.8;HHSteC: 22.2;U-2197: 11.1 +NARFL FLJ21988, HPRN, IOP1, NAR1, PRN ENSG00000103245 Nuclear prelamin A recognition factor like 16 729753-741329 Predicted intracellular proteins Evidence at protein level HPA040851 Approved Approved Plasma membrane
Cytosol Cervical cancer:1.32e-5 (favourable), Renal cancer:9.83e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 19.3 Expressed in all +MTHFSD FLJ12998 ENSG00000103248 Methenyltetrahydrofolate synthetase domain containing 16 86530176-86555235 Predicted intracellular proteins Evidence at protein level HPA041333 Uncertain Approved Nucleus
Vesicles Colorectal cancer:9.88e-5 (unfavourable) Expressed in all Expressed in all testis: 33.0 Mixed +CLCN7 CLC-7, CLC7, OPTA2, PPP1R63 ENSG00000103249 Chloride voltage-gated channel 7 16 1444934-1475580 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA043019, HPA043586 Supported Supported Nucleoplasm Testis cancer:3.21e-4 (unfavourable), Head and neck cancer:5.23e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 41.2 Expressed in all +HAGHL MGC2605 ENSG00000103253 Hydroxyacylglutathione hydrolase-like 16 726936-735525 Predicted intracellular proteins Evidence at transcript level HPA074402 Approved Renal cancer:1.18e-5 (favourable) Expressed in all Tissue enhanced cerebral cortex: 9.1 spleen: 4.4 Cell line enhanced RPMI-8226: 44.3;U-266/70: 49.9 +FAM173A C16orf24, MGC2494 ENSG00000103254 Family with sequence similarity 173 member A 16 720581-722601 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046262 Enhanced Approved Cytosol Renal cancer:4.24e-5 (favourable), Head and neck cancer:8.88e-4 (favourable) Expressed in all Mixed spleen: 9.3 Cell line enhanced U-266/70: 49.3 +SLC7A5 CD98, D16S469E, E16, LAT1, MPE16 ENSG00000103257 Solute carrier family 7 member 5 16 87830023-87869488 Predicted membrane proteins, Transporters Evidence at protein level HPA052673, HPA056077 Approved Supported Vesicles
Plasma membrane
Cytosol Renal cancer:0.00e+0 (unfavourable), Lung cancer:2.43e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 90.3;testis: 84.3 bone marrow: 66.1 Expressed in all +METRN C16orf23, MGC2601 ENSG00000103260 Meteorin, glial cell differentiation regulator 16 715115-719655 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051164 Approved Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all Tissue enhanced cerebral cortex: 64.7 fallopian tube: 38.3 Expressed in all +FBXO31 FBX14, Fbx31, FBXO14, MGC15419 ENSG00000103264 F-box protein 31 16 87326987-87392142 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030150 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Pancreatic cancer:9.16e-5 (favourable) Expressed in all Expressed in all adipose tissue: 24.8 Expressed in all +STUB1 CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1 ENSG00000103266 STIP1 homology and U-box containing protein 1 16 680224-682870 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB037202, CAB037209, HPA041222, HPA043531 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:6.49e-9 (favourable) Expressed in all Expressed in all cerebral cortex: 137.7 Expressed in all +RHBDL1 RHBDL, RRP ENSG00000103269 Rhomboid like 1 16 675666-678268 Enzymes, Predicted membrane proteins Evidence at protein level HPA030359, HPA030360, HPA046593 Uncertain Approved Nucleoplasm Breast cancer:8.12e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 8.0 adrenal gland: 3.3 Mixed +NUBP1 NBP1, NBP35 ENSG00000103274 Nucleotide binding protein 1 16 10743786-10769351 Predicted intracellular proteins Evidence at protein level HPA041656, HPA041799 Enhanced Supported Cytosol Renal cancer:7.61e-8 (favourable), Cervical cancer:2.81e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 55.1 Expressed in all +UBE2I UBC9 ENSG00000103275 Ubiquitin conjugating enzyme E2 I 16 1308880-1327018 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA003909, CAB009021 Approved Enhanced Cytosol Thyroid cancer:5.68e-4 (favourable), Liver cancer:7.50e-4 (unfavourable) Expressed in all Expressed in all ovary: 117.1 Expressed in all +ZP2 ZPA ENSG00000103310 Zona pellucida glycoprotein 2 16 21197450-21214510 Predicted membrane proteins Evidence at protein level HPA011296 Approved Not detected Not detected placenta: 0.3 Cell line enriched 35 HDLM-2: 3.4 +MEFV FMF, MEF, TRIM20 ENSG00000103313 MEFV, pyrin innate immunity regulator 16 3242028-3256627 Disease related genes, Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced appendix: 8.1;spleen: 7.0 bone marrow: 4.2 Cell line enhanced THP-1: 4.4 +CRYM DFNA40 ENSG00000103316 Crystallin mu 16 21238874-21303083 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019086, HPA030619 Enhanced Supported Cytosol Tissue enhanced Group enriched 6 cerebral cortex: 51.1;heart muscle: 47.8;kidney: 28.4;prostate: 24.7;urinary bladder: 14.8 lung: 5.7 Cell line enhanced HEL: 9.4;RPTEC TERT1: 32.9;U-87 MG: 8.7 +EEF2K eEF-2K ENSG00000103319 Eukaryotic elongation factor 2 kinase 16 22206282-22288732 Enzymes, Predicted intracellular proteins Evidence at protein level CAB007818, HPA056061 Approved Approved Nucleoplasm Renal cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all skin: 54.3 Expressed in all +CAPN15 SOLH ENSG00000103326 Calpain 15 16 527717-554636 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011960 Uncertain Approved Nucleus Expressed in all Mixed small intestine: 17.8 Expressed in all +PIEZO1 FAM38A, KIAA0233 ENSG00000103335 Piezo type mechanosensitive ion channel component 1 16 88715343-88785211 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA047185 Uncertain Renal cancer:8.89e-7 (unfavourable), Lung cancer:2.36e-5 (unfavourable), Cervical cancer:2.37e-4 (unfavourable), Ovarian cancer:3.78e-4 (unfavourable) Expressed in all Mixed adipose tissue: 42.0 Expressed in all +GSPT1 eRF3a, ETF3A, GST1 ENSG00000103342 G1 to S phase transition 1 16 11868128-11916082 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052488 Approved Approved Vesicles
Cytosol Colorectal cancer:2.10e-5 (favourable), Renal cancer:3.06e-5 (favourable), Liver cancer:7.94e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 131.6 Expressed in all +ZNF174 ZSCAN8 ENSG00000103343 Zinc finger protein 174 16 3401235-3409370 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009656 Approved Supported Nucleoplasm
Actin filaments
Cytosol Expressed in all Expressed in all parathyroid gland: 28.3 Expressed in all +CLUAP1 CFAP22, FAP22, FLJ13297, IFT38, KIAA0643 ENSG00000103351 Clusterin associated protein 1 16 3500924-3539048 Predicted intracellular proteins Evidence at protein level HPA036976, HPA044191 Uncertain Supported Nucleoplasm
Vesicles Endometrial cancer:3.01e-4 (favourable) Expressed in all Expressed in all testis: 71.9 Mixed +UBFD1 FLJ38870, FLJ42145, UBPH ENSG00000103353 Ubiquitin family domain containing 1 16 23557362-23574389 Predicted intracellular proteins Evidence at protein level HPA051746 Approved Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 56.5 Expressed in all +PRSS33 EOS ENSG00000103355 Protease, serine 33 16 2783953-2787948 Enzymes, Predicted secreted proteins Evidence at protein level HPA058082 Uncertain Tissue enhanced Tissue enriched 7 fallopian tube: 7.4 small intestine: 1.0 Group enriched 10 HMC-1: 2.4;SK-MEL-30: 4.5;U-2 OS: 2.1 +EARS2 KIAA1970, MSE1 ENSG00000103356 Glutamyl-tRNA synthetase 2, mitochondrial 16 23522014-23557731 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043289, HPA043633 Approved Supported Nucleoplasm
Mitochondria Renal cancer:3.16e-6 (favourable), Pancreatic cancer:7.20e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 32.9 Expressed in all +ELOB SIII, TCEB2 ENSG00000103363 Elongin B 16 2771414-2777297 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all fallopian tube: 355.1 Expressed in all +GGA2 KIAA1080, VEAR ENSG00000103365 Golgi associated, gamma adaptin ear containing, ARF binding protein 2 16 23463542-23521995 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB034422, HPA043313, HPA063634 Approved Enhanced Golgi apparatus Cervical cancer:1.71e-5 (favourable), Renal cancer:3.91e-5 (favourable), Head and neck cancer:9.70e-5 (favourable), Lung cancer:1.68e-4 (favourable), Testis cancer:4.15e-4 (unfavourable) Expressed in all Expressed in all lymph node: 87.0 Expressed in all +AQP8 ENSG00000103375 Aquaporin 8 16 25215731-25228940 Predicted membrane proteins, Transporters Evidence at protein level HPA046259 Enhanced Group enriched Group enriched 129 colon: 321.2;pancreas: 269.5;rectum: 166.5 smooth muscle: 1.9 Not detected +CPPED1 CSTP1, FLJ11151 ENSG00000103381 Calcineurin like phosphoesterase domain containing 1 16 12659799-12804017 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040938, HPA041970 Uncertain Supported Plasma membrane
Cytosol Renal cancer:1.62e-9 (favourable), Breast cancer:9.72e-4 (unfavourable) Expressed in all Expressed in all spleen: 41.0 Cell line enhanced Hep G2: 97.8;HMC-1: 114.2 +USP31 KIAA1203 ENSG00000103404 Ubiquitin specific peptidase 31 16 23061406-23149270 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006937 Uncertain Approved Cytosol Renal cancer:4.41e-5 (unfavourable) Expressed in all Mixed testis: 22.2 Expressed in all +HMOX2 HO-2 ENSG00000103415 Heme oxygenase 2 16 4474690-4510347 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025464, HPA040611 Supported Approved Vesicles
Cytosol Renal cancer:8.98e-6 (favourable), Endometrial cancer:7.91e-4 (favourable) Expressed in all Expressed in all testis: 97.6 Expressed in all +DNAJA3 hTid-1, TID1 ENSG00000103423 DnaJ heat shock protein family (Hsp40) member A3 16 4425805-4456775 Predicted intracellular proteins Evidence at protein level CAB016095, HPA040875, HPA044229 Approved Supported Mitochondria Renal cancer:1.79e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 25.4 Expressed in all +CORO7-PAM16 ENSG00000103426 CORO7-PAM16 readthrough 16 4340251-4420494 Predicted intracellular proteins Evidence at protein level HPA041657, HPA053586, HPA062721 Uncertain Approved Nucleoplasm
Microtubules
Mitochondria Not detected Not detected testis: 0.2 Not detected +BFAR BAR, RNF47 ENSG00000103429 Bifunctional apoptosis regulator 16 14632815-14669236 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Pancreatic cancer:4.74e-5 (unfavourable) Expressed in all Expressed in all placenta: 23.4 Expressed in all +SALL1 Hsal1, TBS, ZNF794 ENSG00000103449 Spalt like transcription factor 1 16 51135975-51151367 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049829 Uncertain Approved Nucleus
Cytosol Renal cancer:1.91e-7 (favourable), Endometrial cancer:1.28e-4 (favourable) Group enriched Tissue enhanced thyroid gland: 40.1 cerebral cortex: 30.3 Cell line enhanced AF22: 29.2;NTERA-2: 48.0;RPTEC TERT1: 30.7;U-87 MG: 45.3 +TOX3 CAGF9, TNRC9 ENSG00000103460 TOX high mobility group box family member 3 16 52438005-52547802 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA040376 Enhanced Approved Nucleoplasm Renal cancer:3.08e-12 (favourable), Urothelial cancer:3.95e-4 (favourable) Mixed Mixed stomach: 18.0 Cell line enhanced AF22: 39.9;HAP1: 20.6;RT4: 62.7;SCLC-21H: 31.8 +RBL2 p130, Rb2 ENSG00000103479 RB transcriptional corepressor like 2 16 53433977-53491649 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016547, HPA019703 Supported Approved Nucleus
Nucleoli
Cytosol Renal cancer:3.57e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 149.6 Expressed in all +QPRT QPRTase ENSG00000103485 Quinolinate phosphoribosyltransferase 16 29679008-29698699 Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA011887 Approved Breast cancer:5.10e-5 (unfavourable), Glioma:7.45e-4 (unfavourable) Expressed in all Expressed in all kidney: 112.3 Cell line enhanced EFO-21: 469.3 +XYLT1 PXYLT1, XT-I ENSG00000103489 Xylosyltransferase 1 16 17101769-17470881 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA007478, HPA007966 Approved Mixed Mixed cervix, uterine: 12.2 Cell line enhanced ASC diff: 38.1;U-2197: 54.3 +PYCARD ASC, CARD5, TMS-1 ENSG00000103490 PYD and CARD domain containing 16 31201485-31203450 Predicted intracellular proteins Evidence at protein level CAB006853, CAB015948, HPA049074, HPA054496 Enhanced Supported Nucleus
Nucleoli
Cytosol Renal cancer:6.09e-7 (unfavourable) Expressed in all Mixed duodenum: 51.4 Cell line enhanced MCF7: 97.4;NB-4: 127.0;THP-1: 98.8 +RPGRIP1L CORS3, FTM, JBTS7, KIAA1005, MKS5, NPHP8, PPP1R134 ENSG00000103494 RPGRIP1 like 16 53597683-53703938 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039405, HPA040530 Uncertain Supported Plasma membrane
Cytosol Renal cancer:5.95e-4 (unfavourable), Breast cancer:6.93e-4 (unfavourable) Mixed Tissue enhanced testis: 27.9 parathyroid gland: 19.3 Expressed in all +MAZ Pur-1, ZF87, Zif87, ZNF801 ENSG00000103495 MYC associated zinc finger protein 16 29806106-29811164 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA048315, HPA059495, HPA065930 Approved Enhanced Nucleus Thyroid cancer:2.22e-4 (unfavourable), Renal cancer:5.15e-4 (unfavourable) Expressed in all Expressed in all prostate: 197.0 Expressed in all +STX4 p35-2, STX4A ENSG00000103496 Syntaxin 4 16 31032889-31042975 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA001330 Approved Enhanced Plasma membrane Renal cancer:2.88e-9 (unfavourable), Cervical cancer:3.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 64.5 Expressed in all +CDIPT PIS, PIS1 ENSG00000103502 CDP-diacylglycerol--inositol 3-phosphatidyltransferase 16 29858357-29863736 Enzymes, Predicted membrane proteins Evidence at protein level HPA056597 Approved Approved Nucleoplasm
Nuclear membrane
Plasma membrane Cervical cancer:9.40e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 112.7 Expressed in all +BCKDK ENSG00000103507 Branched chain ketoacid dehydrogenase kinase 16 31106107-31112791 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017995, HPA056067 Supported Supported Mitochondria Expressed in all Expressed in all parathyroid gland: 34.3 Expressed in all +KAT8 FLJ14040, hMOF, MOF, MYST1, ZC2HC8 ENSG00000103510 Lysine acetyltransferase 8 16 31115754-31131393 Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA066324 Supported Nucleoplasm Lung cancer:6.34e-4 (favourable) Expressed in all Expressed in all ovary: 61.6 Expressed in all +NOMO1 PM5 ENSG00000103512 NODAL modulator 1 16 14833681-14896160 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025192, HPA046697, HPA061174 Approved Approved Endoplasmic reticulum Urothelial cancer:3.15e-4 (unfavourable) Expressed in all Mixed thyroid gland: 11.9 Cell line enhanced Hep G2: 80.5;SiHa: 142.9 +IL21R CD360 ENSG00000103522 Interleukin 21 receptor 16 27402162-27452042 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level HPA042296 Uncertain Uncertain Plasma membrane
Cytosol Head and neck cancer:7.29e-4 (favourable) Mixed Tissue enhanced appendix: 15.8;lymph node: 28.8;tonsil: 17.4 spleen: 7.5 Cell line enhanced HDLM-2: 102.6;Karpas-707: 35.4;RH-30: 36.0;RPMI-8226: 42.7 +SYT17 ENSG00000103528 Synaptotagmin 17 16 19167971-19268334 Predicted intracellular proteins Evidence at protein level HPA042059 Approved Nucleus
Cytosol Mixed Tissue enhanced cerebral cortex: 39.8;parathyroid gland: 32.6 prostate: 14.9 Cell line enhanced BEWO: 13.7;CAPAN-2: 24.6;MCF7: 16.6 +TMC5 FLJ13593 ENSG00000103534 Transmembrane channel like 5 16 19410496-19499113 Predicted membrane proteins Evidence at protein level HPA040810, HPA042037 Enhanced Approved Nucleus
Plasma membrane Liver cancer:7.96e-4 (unfavourable) Mixed Tissue enhanced small intestine: 59.1 duodenum: 45.4 Cell line enriched 6 CAPAN-2: 61.8 +CCP110 CP110, KIAA0419 ENSG00000103540 Centriolar coiled-coil protein 110 16 19523811-19553408 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039402 Approved Supported Centrosome Expressed in all Tissue enhanced testis: 65.2 cerebral cortex: 29.7 Expressed in all +C16orf62 MGC16824 ENSG00000103544 Chromosome 16 open reading frame 62 16 19555240-19706793 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042969, HPA053547 Uncertain Approved Mitochondria Renal cancer:1.31e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 69.5 Mixed +SLC6A2 NAT1, NET, NET1, SLC6A5 ENSG00000103546 Solute carrier family 6 member 2 16 55655604-55706192 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA004057, HPA076311, CAB078195 Enhanced Supported Approved Mitochondria
Cytosol Tissue enhanced Tissue enhanced adrenal gland: 29.2;placenta: 18.4;skin: 15.7 testis: 11.4 Cell line enriched 35 SH-SY5Y: 519.4 +RNF40 BRE1B, KIAA0661, RBP95, STARING ENSG00000103549 Ring finger protein 40 16 30761745-30776307 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041330, HPA054227 Approved Enhanced Nucleoplasm Renal cancer:8.11e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 78.9 Expressed in all +KNOP1 101F10.1, C16orf88, FAM191A, TSG118 ENSG00000103550 Lysine rich nucleolar protein 1 16 19701934-19718235 Predicted intracellular proteins Evidence at protein level HPA041079, HPA066169 Uncertain Supported Nucleoli
Cytosol Liver cancer:3.75e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.3 Expressed in all +AQP9 HsT17287, SSC1 ENSG00000103569 Aquaporin 9 15 58138169-58185911 Predicted membrane proteins Evidence at protein level HPA074762, CAB075684 Enhanced Renal cancer:5.72e-11 (unfavourable) Tissue enriched Tissue enhanced appendix: 102.4;liver: 353.0 epididymis: 50.3 Cell line enriched 37 U-87 MG: 27.9 +AAGAB FLJ11506, p34 ENSG00000103591 Alpha- and gamma-adaptin binding protein 15 67201033-67255195 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039371, HPA040174 Supported Supported Nuclear speckles
Cytosol Renal cancer:1.36e-4 (favourable), Thyroid cancer:9.48e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 55.7 Expressed in all +IQCH FLJ12476 ENSG00000103599 IQ motif containing H 15 67254800-67502260 Predicted intracellular proteins Evidence at protein level HPA040845 Uncertain Approved Cytosol Mixed Tissue enhanced fallopian tube: 10.8;testis: 21.1 parathyroid gland,thyroid gland: 6.8 Mixed +LACTB FLJ14902, MRPL56 ENSG00000103642 Lactamase beta 15 63121800-63142061 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036361, HPA036362 Enhanced Supported Mitochondria Expressed in all Expressed in all testis: 39.7 Expressed in all +CORO2B ClipinC, KIAA0925 ENSG00000103647 Coronin 2B 15 68578969-68727806 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017960 Enhanced Approved Plasma membrane
Focal adhesion sites Group enriched Tissue enhanced cerebral cortex: 73.3;fallopian tube: 36.7 ovary: 17.9 Cell line enhanced ASC TERT1: 40.2;HSkMC: 30.2;hTEC/SVTERT24-B: 34.6;U-87 MG: 57.2 +CSK ENSG00000103653 C-src tyrosine kinase 15 74782057-74803198 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011203, HPA026488, HPA028425 Approved Approved Approved Vesicles
Cytosol Cervical cancer:5.14e-5 (favourable), Stomach cancer:1.07e-4 (favourable), Renal cancer:1.74e-4 (unfavourable), Endometrial cancer:8.22e-4 (favourable) Expressed in all Expressed in all lymph node: 195.2 Expressed in all +HERC1 p532, p619 ENSG00000103657 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 15 63608618-63833942 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA049749 Uncertain Renal cancer:1.36e-6 (favourable), Head and neck cancer:4.87e-5 (favourable), Pancreatic cancer:3.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 58.6 Expressed in all +TRIP4 HsT17391, ZC2HC5 ENSG00000103671 Thyroid hormone receptor interactor 4 15 64387748-64455303 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA016605, HPA050666 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:6.34e-6 (favourable) Expressed in all Expressed in all thyroid gland: 42.2 Expressed in all +MTFMT FMT1 ENSG00000103707 Mitochondrial methionyl-tRNA formyltransferase 15 65001512-65029639 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA040710 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.31e-8 (favourable) Expressed in all Mixed smooth muscle: 2.7 Mixed +RASL12 RIS ENSG00000103710 RAS like family 12 15 65053337-65076690 Predicted intracellular proteins Evidence at protein level Renal cancer:7.20e-5 (unfavourable), Urothelial cancer:2.17e-4 (unfavourable) Expressed in all Tissue enhanced seminal vesicle: 101.5 prostate: 64.1 Cell line enhanced CACO-2: 11.7;EFO-21: 20.5;NTERA-2: 9.4 +AP3B2 NAPTB ENSG00000103723 Adaptor related protein complex 3 beta 2 subunit 15 82659281-82709914 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039467, HPA039818 Enhanced Mixed Group enriched 6 cerebral cortex: 36.2;parathyroid gland: 7.4 adrenal gland: 3.8 Cell line enhanced RT4: 11.4;SCLC-21H: 26.6;SH-SY5Y: 18.5 +ACSBG1 BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352 ENSG00000103740 Acyl-CoA synthetase bubblegum family member 1 15 78167468-78245688 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041642, CAB045955, HPA058869 Approved Approved Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 25.6;skin: 13.3 adrenal gland: 8.1 Cell line enhanced NTERA-2: 3.3 +IGDCC4 LOC57722, NOPE ENSG00000103742 Immunoglobulin superfamily DCC subclass member 4 15 65381464-65423072 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA008510, HPA008576 Approved Approved Approved Nucleoplasm
Cytosol Tissue enhanced Mixed ovary: 9.0 Cell line enhanced AF22: 8.1;CAPAN-2: 6.4;NTERA-2: 6.2 +RAB11A YL8 ENSG00000103769 RAB11A, member RAS oncogene family 15 65726054-65891991 Predicted intracellular proteins Evidence at protein level CAB013097, HPA051697, HPA060686 Approved Enhanced Vesicles
Microtubule organizing center Renal cancer:1.46e-5 (favourable), Pancreatic cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all esophagus: 524.8 Expressed in all +CTSH ACC-4, ACC-5, ACC4, ACC5, CPSB ENSG00000103811 Cathepsin H 15 78921058-78949574 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000458, HPA003524 Enhanced Supported Vesicles
Cytosol
Cytoplasmic bodies Endometrial cancer:6.90e-4 (favourable) Expressed in all Expressed in all lung: 570.6 Cell line enhanced CAPAN-2: 219.5;HaCaT: 161.7;RT4: 558.6 +TTC23 FLJ12572, HCC-8 ENSG00000103852 Tetratricopeptide repeat domain 23 15 99136323-99251223 Predicted intracellular proteins Evidence at protein level HPA039806, HPA040369 Uncertain Approved Plasma membrane
Cytosol Endometrial cancer:1.07e-4 (favourable), Breast cancer:3.17e-4 (favourable) Expressed in all Mixed testis: 24.3 Mixed +CD276 B7-H3, B7H3, B7RP-2 ENSG00000103855 CD276 molecule 15 73683966-73714518 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA009285, HPA017139, CAB017826 Enhanced Approved Vesicles Renal cancer:6.31e-5 (unfavourable), Liver cancer:9.81e-4 (unfavourable) Expressed in all Mixed placenta: 30.2 Cell line enhanced U-2197: 176.1 +FAH ENSG00000103876 Fumarylacetoacetate hydrolase 15 80152490-80186946 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041370, HPA044093 Enhanced Approved Cytosol Head and neck cancer:8.51e-4 (unfavourable) Expressed in all Expressed in all liver: 151.9 Cell line enhanced HHSteC: 261.9 +CEMIP HYBID, IR2155535, KIAA1199, TMEM2L ENSG00000103888 Cell migration inducing hyaluronan binding protein 15 80779343-80951776 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Urothelial cancer:2.65e-4 (unfavourable) Expressed in all Tissue enhanced endometrium: 53.2 appendix: 15.8 Cell line enhanced BJ: 172.4;BJ hTERT+: 260.3;fHDF/TERT166: 200.3;HSkMC: 122.9;U-138 MG: 89.3 +RPAP1 DKFZP727M111, FLJ12732, KIAA1403, MGC858 ENSG00000103932 RNA polymerase II associated protein 1 15 41517176-41544269 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041739 Approved Approved Nucleoplasm
Cytosol Thyroid cancer:9.32e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 13.3 Expressed in all +HOMER2 CPD, Cupidin, HOMER-2, HOMER-2A, HOMER-2B, Vesl-2 ENSG00000103942 Homer scaffolding protein 2 15 82836946-82986153 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040134, CAB079014 Uncertain Supported Mixed Expressed in all prostate: 92.9 Cell line enhanced Karpas-707: 66.5;SCLC-21H: 59.9 +EHD4 PAST4 ENSG00000103966 EH domain containing 4 15 41895939-41972578 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049890, HPA049986, HPA052729, HPA066751 Approved Approved Plasma membrane Expressed in all Expressed in all thyroid gland: 24.8 Cell line enhanced TIME: 140.3 +TMEM87A DKFZP564G2022 ENSG00000103978 Transmembrane protein 87A 15 42210452-42273663 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018104, HPA018189 Enhanced Supported Golgi apparatus Expressed in all Expressed in all prostate: 124.3 Expressed in all +ZNF106 SH3BP3, ZFP106, ZNF474 ENSG00000103994 Zinc finger protein 106 15 42412823-42491123 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054267 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all skeletal muscle: 144.2 Expressed in all +CEP152 KIAA0912, MCPH9, SCKL5 ENSG00000103995 Centrosomal protein 152 15 48712928-48811146 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039408 Approved Supported Centrosome Mixed Tissue enhanced testis: 18.1 bone marrow: 10.2 Expressed in all +ATP8B4 ATPIM, KIAA1939 ENSG00000104043 ATPase phospholipid transporting 8B4 (putative) 15 49858238-50182817 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040254 Approved Approved Nucleoplasm
Vesicles Mixed Tissue enhanced bone marrow: 23.0 endometrium: 9.3 Cell line enhanced HMC-1: 32.2;THP-1: 16.5;U-937: 60.0 +OCA2 BEY, BEY1, BEY2, D15S12, EYCL, EYCL2, EYCL3, P ENSG00000104044 OCA2 melanosomal transmembrane protein 15 27754875-28099358 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Tissue enhanced skin: 7.4;thyroid gland: 5.8 testis: 2.5 Group enriched 6 SH-SY5Y: 6.3;SK-MEL-30: 18.3 +DTWD1 MDS009, MGC111207 ENSG00000104047 DTW domain containing 1 15 49620980-49656232 Predicted intracellular proteins Evidence at protein level HPA042214 Uncertain Approved Nucleus
Nucleoli
Vesicles Expressed in all Expressed in all cervix, uterine: 39.5 Expressed in all +TGM5 TGX ENSG00000104055 Transglutaminase 5 15 43232595-43266857 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Mixed Group enriched 7 esophagus: 8.4;skin: 22.3 breast: 2.3 Cell line enriched 8 HEL: 16.7 +FAM189A1 KIAA0574, TMEM228 ENSG00000104059 Family with sequence similarity 189 member A1 15 29120254-29570723 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA009410, HPA010637 Uncertain Supported Nucleus Mixed Tissue enhanced cerebral cortex: 2.2;parathyroid gland: 2.0 colon,testis: 0.8 Cell line enhanced EFO-21: 4.4;HDLM-2: 11.1;REH: 2.6 +GABPB1 E4TF1-47, GABPB, GABPB2 ENSG00000104064 GA binding protein transcription factor beta subunit 1 15 50275392-50355408 Predicted intracellular proteins Evidence at protein level HPA019653, HPA067444 Supported Supported Nucleoplasm
Cytoplasmic bodies Renal cancer:2.53e-4 (unfavourable) Expressed in all Expressed in all testis: 28.7 Expressed in all +TJP1 DKFZp686M05161, MGC133289, ZO-1 ENSG00000104067 Tight junction protein 1 15 29699367-29968865 Predicted intracellular proteins Evidence at protein level HPA001636, HPA001637, CAB010822 Enhanced Enhanced Cell Junctions Renal cancer:1.72e-4 (favourable) Expressed in all Mixed cerebral cortex: 49.6 Mixed +BMF FLJ00065 ENSG00000104081 Bcl2 modifying factor 15 40087890-40108892 Predicted intracellular proteins Evidence at protein level HPA010120 Approved Approved Nucleoplasm Head and neck cancer:1.83e-4 (favourable), Liver cancer:6.32e-4 (unfavourable) Expressed in all Mixed endometrium: 26.1 Cell line enhanced HMC-1: 38.8 +DMXL2 KIAA0856, RC3 ENSG00000104093 Dmx like 2 15 51447711-51622833 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039375 Approved Renal cancer:7.50e-4 (unfavourable) Expressed in all Mixed epididymis: 26.3 Cell line enhanced U-937: 50.3 +SCG3 FLJ90833, SgIII ENSG00000104112 Secretogranin III 15 51681353-51721031 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006880, CAB033274, HPA053715 Enhanced Approved Enhanced Vesicles Group enriched Tissue enriched 13 cerebral cortex: 278.4 adrenal gland: 21.9 Group enriched 8 NTERA-2: 50.4;SCLC-21H: 140.8;SH-SY5Y: 60.1 +DNAJC17 FLJ10634 ENSG00000104129 DnaJ heat shock protein family (Hsp40) member C17 15 40765155-40807478 Predicted intracellular proteins Evidence at protein level HPA040914, HPA041187 Approved Approved Nucleoplasm Colorectal cancer:5.89e-4 (unfavourable) Expressed in all Expressed in all endometrium: 24.4 Expressed in all +EIF3J eIF3-alpha, eIF3-p35, eIF3j, EIF3S1 ENSG00000104131 Eukaryotic translation initiation factor 3 subunit J 15 44537057-44563029 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050977 Approved Enhanced Cytosol Urothelial cancer:4.96e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 69.3 Expressed in all +SPG11 FLJ21439, KIAA1840 ENSG00000104133 SPG11, spatacsin vesicle trafficking associated 15 44562696-44663678 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040412, HPA040947 Approved Supported Nucleoli
Plasma membrane
Cytosol Renal cancer:6.28e-5 (favourable) Expressed in all Expressed in all parathyroid gland,thyroid gland: 48.3 Expressed in all +RHOV ARHV, Chp, WRCH2 ENSG00000104140 Ras homolog family member V 15 40872214-40874289 Predicted intracellular proteins Evidence at protein level HPA053343 Enhanced Lung cancer:2.33e-4 (unfavourable), Pancreatic cancer:4.19e-4 (unfavourable) Tissue enhanced Tissue enhanced esophagus: 71.5;skin: 72.6 tonsil: 20.2 Cell line enhanced HaCaT: 66.2;SK-BR-3: 237.1 +VPS18 KIAA1475, PEP3 ENSG00000104142 VPS18, CORVET/HOPS core subunit 15 40894430-40903975 Predicted intracellular proteins Evidence at protein level HPA040701 Approved Renal cancer:1.61e-6 (favourable), Pancreatic cancer:8.69e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 15.8 Expressed in all +OIP5 CT86, hMIS18beta, MIS18B ENSG00000104147 Opa interacting protein 5 15 41309268-41332621 Predicted intracellular proteins Evidence at protein level HPA052271, HPA059602 Enhanced Supported Nucleoplasm Pancreatic cancer:9.34e-5 (unfavourable), Liver cancer:1.79e-4 (unfavourable), Lung cancer:2.26e-4 (unfavourable) Mixed Tissue enriched 6 testis: 37.2 lymph node: 6.7 Mixed +SLC30A4 ZNT4 ENSG00000104154 Solute carrier family 30 member 4 15 45479611-45522807 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018178 Uncertain Pancreatic cancer:6.02e-4 (favourable) Tissue enriched Tissue enriched 5 prostate: 64.5 testis: 11.8 Mixed +BLOC1S6 HPS9, PA, PLDN ENSG00000104164 Biogenesis of lysosomal organelles complex 1 subunit 6 15 45587123-45615999 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039928 Approved Expressed in all Expressed in all thyroid gland: 82.7 Expressed in all +MYEF2 FLJ11213, HsT18564, KIAA1341, MEF-2 ENSG00000104177 Myelin expression factor 2 15 48134631-48178517 Predicted intracellular proteins Evidence at protein level HPA004883 Supported Supported Nucleoplasm Mixed Tissue enhanced testis: 51.3 cerebral cortex: 47.2 Cell line enhanced AF22: 100.6;SCLC-21H: 106.7 +SGK3 SGK2, SGKL ENSG00000104205 Serum/glucocorticoid regulated kinase family member 3 8 66712418-66862022 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006699, HPA027146 Supported Approved Nucleoplasm
Vesicles Breast cancer:5.52e-6 (favourable), Cervical cancer:8.28e-4 (favourable), Pancreatic cancer:9.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 48.5 Mixed +PDGFRL PRLTS ENSG00000104213 Platelet derived growth factor receptor like 8 17576433-17644071 Disease related genes, Predicted secreted proteins Evidence at protein level HPA052801 Approved Nucleus
Nucleoli
Golgi apparatus Renal cancer:0.00e+0 (unfavourable) Expressed in all Mixed breast: 49.2 Cell line enhanced AN3-CA: 131.2;BJ hTERT+: 93.6;HSkMC: 44.1 +CSPP1 CSPP, FLJ22490, JBTS21 ENSG00000104218 Centrosome and spindle pole associated protein 1 8 67062426-67196263 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056174 Supported Microtubule organizing center Thyroid cancer:2.98e-4 (unfavourable) Expressed in all Expressed in all testis: 33.9 Expressed in all +ZDHHC2 ZNF372 ENSG00000104219 Zinc finger DHHC-type containing 2 8 17156029-17224799 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023331 Uncertain Renal cancer:3.24e-4 (favourable) Expressed in all Expressed in all thyroid gland: 53.7 Mixed +BRF2 BRFU, FLJ11052, TFIIIB50 ENSG00000104221 BRF2, RNA polymerase III transcription initiation factor subunit 8 37843268-37849904 Predicted intracellular proteins Evidence at protein level CAB019269, HPA023378 Enhanced Approved Nucleoli Expressed in all Expressed in all ovary: 16.1 Expressed in all +TRIM35 HLS5, KIAA1098, MAIR ENSG00000104228 Tripartite motif containing 35 8 27284887-27311319 Predicted intracellular proteins Evidence at protein level HPA019647 Approved Approved Nucleoplasm Renal cancer:5.59e-7 (favourable), Head and neck cancer:1.38e-4 (favourable) Expressed in all Expressed in all skin: 14.6 Expressed in all +ZFAND1 FLJ14007 ENSG00000104231 Zinc finger AN1-type containing 1 8 81701334-81732903 Predicted intracellular proteins Evidence at protein level HPA023383 Approved Approved Centrosome
Cytosol Expressed in all Expressed in all thyroid gland: 92.5 Expressed in all +RP1 DCDC4A, ORP1 ENSG00000104237 RP1, axonemal microtubule associated 8 54554361-54871720 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042257 Supported Not detected Tissue enhanced fallopian tube: 16.3;lung: 5.4 testis: 2.4 Cell line enhanced HDLM-2: 4.8;RPTEC TERT1: 7.7;U-2197: 2.2 +CA2 CA-II, CAII, Car2 ENSG00000104267 Carbonic anhydrase 2 8 85463852-85481493 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001550, CAB010102 Enhanced Renal cancer:5.57e-6 (favourable) Expressed in all Tissue enhanced colon: 604.8;rectum: 627.5;stomach: 918.8 kidney: 308.3 Group enriched 11 HaCaT: 204.1;HEK 293: 884.1;THP-1: 278.7 +FZD3 ENSG00000104290 Frizzled class receptor 3 8 28494205-28574268 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB024995 Approved Colorectal cancer:1.17e-4 (favourable), Ovarian cancer:3.71e-4 (favourable) Mixed Mixed cerebral cortex: 16.4 Cell line enhanced AF22: 53.7;SCLC-21H: 46.9 +INTS9 CPSF2L, FLJ10871, RC-74 ENSG00000104299 Integrator complex subunit 9 8 28767661-28890242 Predicted intracellular proteins Evidence at protein level HPA051615, HPA066822 Enhanced Nucleoplasm Renal cancer:1.91e-5 (favourable), Lung cancer:7.71e-4 (favourable), Endometrial cancer:9.45e-4 (favourable) Expressed in all Expressed in all testis: 19.8 Expressed in all +RIPK2 CARD3, CARDIAK, RICK, RIP2 ENSG00000104312 Receptor interacting serine/threonine kinase 2 8 89757747-89791063 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015273, HPA016499 Approved Enhanced Cytosol Renal cancer:0.00e+0 (unfavourable), Pancreatic cancer:5.00e-6 (unfavourable), Lung cancer:6.33e-5 (unfavourable), Urothelial cancer:8.05e-4 (favourable) Expressed in all Mixed gallbladder: 13.9 Mixed +EYA1 BOR ENSG00000104313 EYA transcriptional coactivator and phosphatase 1 8 71197433-71362232 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028917 Supported Nucleoplasm
Nuclear bodies Mixed Tissue enhanced parathyroid gland: 81.7;prostate: 21.2 cerebral cortex: 10.7 Cell line enhanced AN3-CA: 28.1;RH-30: 23.1;SH-SY5Y: 57.2 +NBN AT-V1, AT-V2, ATV, NBS, NBS1 ENSG00000104320 Nibrin 8 89933336-90003228 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001429, CAB003836 Supported Approved Nucleoplasm
Golgi apparatus Lung cancer:5.46e-5 (unfavourable), Pancreatic cancer:4.20e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 37.4 Expressed in all +TRPA1 ANKTM1 ENSG00000104321 Transient receptor potential cation channel subfamily A member 1 8 72019917-72075617 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Colorectal cancer:6.57e-4 (favourable) Mixed Tissue enhanced urinary bladder: 29.5 gallbladder: 11.4 Cell line enriched 5 HHSteC: 21.8 +CPQ LDP, PGCP ENSG00000104324 Carboxypeptidase Q 8 96645227-97149654 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023235, HPA024490 Enhanced Supported Golgi apparatus
Vesicles Renal cancer:5.40e-5 (favourable), Glioma:9.75e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 382.5 Cell line enhanced ASC TERT1: 92.2 +DECR1 DECR, SDR18C1 ENSG00000104325 2,4-dienoyl-CoA reductase 1 8 90001405-90052092 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA023160, HPA023162, HPA023238 Enhanced Supported Mitochondria
Cytosol Renal cancer:1.79e-7 (favourable), Breast cancer:1.49e-4 (unfavourable), Urothelial cancer:6.06e-4 (favourable) Expressed in all Expressed in all liver: 262.9 Expressed in all +CALB1 CALB ENSG00000104327 Calbindin 1 8 90058608-90095475 Predicted intracellular proteins Evidence at protein level CAB002138, HPA023099, HPA056734 Enhanced Supported Vesicles Endometrial cancer:1.60e-4 (unfavourable) Mixed Tissue enriched 15 kidney: 336.9 cerebral cortex: 22.5 Cell line enhanced A-431: 116.6;EFO-21: 179.9;NTERA-2: 72.7 +IMPAD1 FLJ20421, gPAPP, IMPA3 ENSG00000104331 Inositol monophosphatase domain containing 1 8 56957933-56993844 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009411 Supported Supported Nucleus
Golgi apparatus
Cytosol Expressed in all Expressed in all parathyroid gland: 52.7 Expressed in all +SFRP1 FRP, FRP-1, SARP2 ENSG00000104332 Secreted frizzled related protein 1 8 41261958-41309497 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB008116, HPA064870 Approved Approved Nucleoli
Cytosol Head and neck cancer:1.55e-4 (favourable), Urothelial cancer:3.12e-4 (unfavourable) Mixed Tissue enhanced breast: 357.2;cervix, uterine: 325.0 endometrium: 231.0 Cell line enhanced BJ hTERT+: 563.8;HBF TERT88: 268.7;RPTEC TERT1: 319.1;WM-115: 275.2 +LAPTM4B LC27 ENSG00000104341 Lysosomal protein transmembrane 4 beta 8 97775057-97853013 Predicted membrane proteins, Transporters Evidence at protein level CAB020782, HPA068830 Uncertain Approved Golgi apparatus Liver cancer:2.70e-6 (unfavourable), Breast cancer:5.63e-4 (unfavourable), Head and neck cancer:5.70e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 133.2 Mixed +UBE2W FLJ11011, UBC-16 ENSG00000104343 Ubiquitin conjugating enzyme E2 W 8 73780097-73878910 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045161, HPA073181 Uncertain Supported Nucleoli Expressed in all Expressed in all testis: 19.6 Expressed in all +POP1 ENSG00000104356 POP1 homolog, ribonuclease P/MRP subunit 8 98117297-98159834 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA066194 Supported Nucleoli Liver cancer:1.26e-6 (unfavourable), Breast cancer:2.54e-4 (unfavourable), Renal cancer:5.97e-4 (unfavourable), Lung cancer:9.88e-4 (unfavourable) Expressed in all Mixed testis: 6.0 Expressed in all +NIPAL2 FLJ13955, NPAL2 ENSG00000104361 NIPA like domain containing 2 8 98189833-98294393 Predicted membrane proteins Evidence at transcript level HPA071759 Uncertain Expressed in all Mixed skin: 62.2 Cell line enhanced ASC diff: 30.5 +IKBKB IKK-beta, IKK2, IKKB, NFKBIKB ENSG00000104365 Inhibitor of nuclear factor kappa B kinase subunit beta 8 42271302-42332653 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA001249, CAB004447 Enhanced Approved Cytosol Urothelial cancer:1.46e-6 (favourable) Expressed in all Mixed parathyroid gland: 18.7 Expressed in all +PLAT ENSG00000104368 Plasminogen activator, tissue type 8 42175233-42207724 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA003412, CAB009335 Supported Approved Actin filaments Renal cancer:4.95e-4 (unfavourable), Breast cancer:7.57e-4 (favourable) Expressed in all Tissue enriched 5 parathyroid gland: 709.4 urinary bladder: 135.9 Cell line enhanced CAPAN-2: 590.7;HMC-1: 372.4;U-2197: 417.3;WM-115: 889.6 +JPH1 JP-1 ENSG00000104369 Junctophilin 1 8 74234700-74321328 Predicted membrane proteins Evidence at protein level HPA008996, HPA009413, CAB013461 Enhanced Supported Nucleus Lung cancer:5.77e-5 (favourable) Mixed Tissue enriched 10 skeletal muscle: 88.0 cerebral cortex: 8.6 Cell line enhanced SK-BR-3: 27.1;T-47d: 24.2 +DKK4 ENSG00000104371 Dickkopf WNT signaling pathway inhibitor 4 8 42374068-42377232 Predicted secreted proteins Evidence at protein level HPA052916 Approved Tissue enriched Tissue enhanced duodenum: 2.4;esophagus: 5.4;testis: 2.7 urinary bladder: 1.4 Cell line enriched 9 Hep G2: 1.4 +STK3 KRS1, MST2 ENSG00000104375 Serine/threonine kinase 3 8 98401403-98942827 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007120, CAB025316 Uncertain Approved Intermediate filaments
Rods & Rings Pancreatic cancer:9.21e-5 (unfavourable), Endometrial cancer:1.53e-4 (unfavourable), Lung cancer:4.25e-4 (unfavourable) Expressed in all Expressed in all endometrium: 41.5 Mixed +GDAP1 CMT2K, CMT4, CMT4A ENSG00000104381 Ganglioside induced differentiation associated protein 1 8 74321130-74488872 Disease related genes, Predicted membrane proteins Evidence at protein level HPA014266, HPA024334 Enhanced Supported Mitochondria
Cytosol Endometrial cancer:1.82e-4 (unfavourable), Lung cancer:2.68e-4 (favourable), Thyroid cancer:4.54e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 76.7 parathyroid gland: 18.3 Cell line enhanced SH-SY5Y: 49.8 +RAB2A RAB2 ENSG00000104388 RAB2A, member RAS oncogene family 8 60516857-60623627 Predicted intracellular proteins Evidence at protein level CAB018781 Approved Breast cancer:8.22e-4 (unfavourable), Endometrial cancer:9.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 108.0 Expressed in all +EIF3E eIF3-p48, eIF3e, EIF3S6, INT6 ENSG00000104408 Eukaryotic translation initiation factor 3 subunit E 8 108201216-108435333 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA023973 Approved Enhanced Nuclear bodies
Cytosol Renal cancer:3.06e-7 (unfavourable) Expressed in all Expressed in all ovary: 731.0 Expressed in all +EMC2 KIAA0103, TTC35 ENSG00000104412 ER membrane protein complex subunit 2 8 108443601-108486918 Predicted intracellular proteins Evidence at protein level HPA022838 Approved Breast cancer:2.64e-4 (unfavourable) Expressed in all Expressed in all testis: 110.0 Expressed in all +ESRP1 FLJ20171, RBM35A ENSG00000104413 Epithelial splicing regulatory protein 1 8 94641074-94707466 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023719, HPA023720, HPA067104 Enhanced Enhanced Nucleoplasm
Nuclear bodies Renal cancer:1.96e-8 (favourable), Pancreatic cancer:2.05e-4 (unfavourable), Endometrial cancer:3.56e-4 (unfavourable), Breast cancer:9.28e-4 (unfavourable) Mixed Mixed skin: 72.8 Cell line enhanced A-431: 122.3;BEWO: 98.9;CAPAN-2: 125.0;hTCEpi: 166.0;RT4: 84.1;T-47d: 103.3 +WISP1 CCN4 ENSG00000104415 WNT1 inducible signaling pathway protein 1 8 133191039-133230344 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA007121, CAB012205 Uncertain Approved Cytosol Renal cancer:1.91e-5 (unfavourable) Expressed in all Mixed smooth muscle: 22.1 Cell line enhanced HSkMC: 85.7;hTEC/SVTERT24-B: 73.5;U-2197: 64.2 +NDRG1 CAP43, DRG1, NDR1, RTP, TDD5 ENSG00000104419 N-myc downstream regulated 1 8 133237171-133302022 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006881 Approved Supported Microtubules
Cytosol Liver cancer:1.47e-4 (unfavourable), Renal cancer:4.13e-4 (unfavourable), Glioma:7.24e-4 (unfavourable) Expressed in all Expressed in all prostate: 535.2 Cell line enhanced hTCEpi: 403.8;hTERT-HME1: 857.9;U-87 MG: 734.9 +ZC2HC1A C8orf70, CGI-62, FAM164A ENSG00000104427 Zinc finger C2HC-type containing 1A 8 78666047-78719765 Predicted intracellular proteins Evidence at protein level HPA024726 Approved Approved Actin filaments
Cytosol Stomach cancer:5.85e-4 (unfavourable), Ovarian cancer:9.00e-4 (unfavourable) Expressed in all Mixed skin: 52.9 Cell line enhanced SK-BR-3: 58.7 +IL7 IL-7 ENSG00000104432 Interleukin 7 8 78675743-78805523 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA019590 Approved Renal cancer:2.69e-4 (unfavourable) Mixed Mixed skin: 10.2 Cell line enhanced HDLM-2: 15.6;HEL: 15.9;HMC-1: 22.1 +STMN2 SCG10, SCGN10 ENSG00000104435 Stathmin 2 8 79610814-79666175 Predicted intracellular proteins Evidence at protein level HPA026922 Supported Approved Endoplasmic reticulum
Vesicles Group enriched Tissue enriched 6 cerebral cortex: 489.4 adrenal gland: 88.0 Cell line enriched 10 SH-SY5Y: 696.7 +ARMC1 Arcp, FLJ10511 ENSG00000104442 Armadillo repeat containing 1 8 65602456-65634217 Predicted intracellular proteins Evidence at protein level HPA026085 Approved Supported Mitochondria Endometrial cancer:2.87e-4 (unfavourable), Breast cancer:4.81e-4 (unfavourable), Liver cancer:7.73e-4 (unfavourable), Pancreatic cancer:9.15e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 34.7 Expressed in all +TRPS1 GC79, LGCR ENSG00000104447 Transcriptional repressor GATA binding 1 8 115408496-115809673 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060380, HPA071767 Enhanced Supported Nucleoplasm Pancreatic cancer:3.16e-4 (unfavourable), Head and neck cancer:9.42e-4 (favourable) Tissue enriched Tissue enhanced breast: 75.9 testis: 22.6 Cell line enhanced SK-BR-3: 58.4;T-47d: 230.2 +SPAG1 CILD28, CT140, FLJ32920, HSD-3.8, SP75, TPIS ENSG00000104450 Sperm associated antigen 1 8 100157906-100259278 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023748, HPA053682 Enhanced Supported Cytosol Urothelial cancer:2.62e-4 (favourable), Renal cancer:3.87e-4 (unfavourable) Expressed in all Tissue enhanced testis: 34.1 rectum: 20.0 Mixed +CHRAC1 CHRAC15, YCL1 ENSG00000104472 Chromatin accessibility complex 1 8 140511298-140517137 Predicted intracellular proteins Evidence at protein level HPA059008 Approved Nucleus Liver cancer:4.88e-5 (unfavourable), Endometrial cancer:2.28e-4 (unfavourable), Pancreatic cancer:5.43e-4 (unfavourable), Ovarian cancer:9.72e-4 (favourable) Expressed in all Expressed in all thyroid gland: 35.0 Expressed in all +NCALD ENSG00000104490 Neurocalcin delta 8 101686543-102124907 Predicted intracellular proteins Evidence at protein level HPA043245 Approved Pancreatic cancer:5.30e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 125.0 Group enriched 5 AF22: 133.9;HDLM-2: 161.9 +SNX16 ENSG00000104497 Sorting nexin 16 8 81799581-81842866 Predicted intracellular proteins Evidence at protein level HPA024730, HPA024731, HPA024817 Approved Supported Vesicles Expressed in all Mixed testis: 27.7 Expressed in all +GML LY6DL ENSG00000104499 Glycosylphosphatidylinositol anchored molecule like 8 142834247-142916506 Predicted secreted proteins, Transporters Evidence at transcript level Not detected Tissue enriched 39 adrenal gland: 251.3 testis: 6.4 Not detected +UBR5 DD5, EDD, EDD1, HYD, KIAA0896 ENSG00000104517 Ubiquitin protein ligase E3 component n-recognin 5 8 102253012-102412841 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA053688 Supported Nucleoplasm
Cytosol Liver cancer:1.26e-4 (unfavourable) Expressed in all Expressed in all testis: 80.2 Expressed in all +GSDMD DF5L, FLJ12150, GSDMDC1 ENSG00000104518 Gasdermin D 8 143553207-143563062 Predicted intracellular proteins, Transporters Evidence at protein level CAB004656, HPA044487 Uncertain Supported Nucleoplasm Renal cancer:1.43e-4 (unfavourable) Expressed in all Expressed in all spleen: 46.5 Mixed +TSTA3 FX, P35B, SDR4E1 ENSG00000104522 Tissue specific transplantation antigen P35B 8 143612618-143618048 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023361 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.59e-4 (unfavourable), Ovarian cancer:2.41e-4 (favourable) Expressed in all Expressed in all stomach: 50.3 Expressed in all +PYCRL FLJ13852 ENSG00000104524 Pyrroline-5-carboxylate reductase-like 8 143603913-143609773 Enzymes, Predicted intracellular proteins Evidence at protein level HPA063416, HPA069706 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Mixed cerebral cortex: 4.1 Expressed in all +EEF1D EF-1D, FLJ20897 ENSG00000104529 Eukaryotic translation elongation factor 1 delta 8 143579697-143599541 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045101, HPA051002 Supported Supported Nucleus
Nucleoli fibrillar center Renal cancer:2.58e-5 (unfavourable), Liver cancer:3.82e-4 (unfavourable) Expressed in all Expressed in all ovary: 606.8 Expressed in all +ANXA13 ANX13 ENSG00000104537 Annexin A13 8 123680794-123737407 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018535, HPA019569, HPA019650, CAB025135 Enhanced Supported Plasma membrane Group enriched Group enriched 5 duodenum: 296.6;fallopian tube: 92.7;gallbladder: 227.6;small intestine: 235.6 rectum: 39.2 Group enriched 16 A549: 25.3;HDLM-2: 13.7 +SQLE ENSG00000104549 Squalene epoxidase 8 124998497-125022283 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018038, HPA020762 Enhanced Uncertain Vesicles
Cytosol Pancreatic cancer:2.73e-4 (unfavourable), Lung cancer:4.67e-4 (unfavourable), Renal cancer:5.70e-4 (unfavourable), Head and neck cancer:7.42e-4 (unfavourable) Expressed in all Mixed testis: 107.8 Expressed in all +SH2D4A FLJ20967, PPP1R38, SH2A ENSG00000104611 SH2 domain containing 4A 8 19313617-19396218 Predicted intracellular proteins Evidence at protein level HPA001871, HPA001919 Enhanced Enhanced Cytosol Renal cancer:6.02e-8 (favourable) Expressed in all Mixed ovary: 44.9 Cell line enhanced fHDF/TERT166: 140.4;U-2197: 121.2 +INTS10 C8orf35, FLJ10569, INT10 ENSG00000104613 Integrator complex subunit 10 8 19817140-19852083 Predicted intracellular proteins Evidence at protein level HPA039129, HPA050570 Uncertain Approved Nucleoplasm
Cytosol Endometrial cancer:1.22e-4 (favourable), Colorectal cancer:4.00e-4 (favourable) Expressed in all Expressed in all thyroid gland: 64.9 Expressed in all +ERI1 3'HEXO, THEX1 ENSG00000104626 Exoribonuclease 1 8 9002147-9116746 Predicted intracellular proteins Evidence at protein level CAB033838, HPA055548, HPA056074 Uncertain Approved Vesicles
Microtubules Colorectal cancer:8.05e-5 (favourable), Renal cancer:1.42e-4 (unfavourable) Expressed in all Mixed testis: 16.8 Expressed in all +SLC39A14 KIAA0062, NET34, ZIP14 ENSG00000104635 Solute carrier family 39 member 14 8 22367249-22434129 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA016508 Approved Approved Endoplasmic reticulum
Golgi apparatus
Plasma membrane Renal cancer:3.79e-7 (unfavourable), Colorectal cancer:5.00e-5 (favourable) Expressed in all Mixed liver: 203.0 Expressed in all +MTMR9 C8orf9, DKFZp434K171, LIP-STYX, MTMR8 ENSG00000104643 Myotubularin related protein 9 8 11284416-11328146 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA070944 Approved Actin filaments
Centrosome Expressed in all Mixed cerebral cortex: 22.4 Expressed in all +LEPROTL1 my047, Vps55 ENSG00000104660 Leptin receptor overlapping transcript-like 1 8 30095398-30177208 Predicted membrane proteins Evidence at protein level HPA047911 Uncertain Renal cancer:1.94e-5 (unfavourable), Colorectal cancer:9.04e-4 (favourable) Expressed in all Expressed in all placenta: 120.0 Expressed in all +DCTN6 WS-3 ENSG00000104671 Dynactin subunit 6 8 30156297-30183640 Predicted intracellular proteins Evidence at protein level HPA024049, HPA024558 Approved Supported Nucleoli
Plasma membrane
Cytosol Renal cancer:5.42e-4 (favourable), Liver cancer:5.51e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 93.9 Expressed in all +R3HCC1 DKFZp564N123 ENSG00000104679 R3H domain and coiled-coil containing 1 8 23270120-23296279 Predicted intracellular proteins Evidence at protein level HPA023073, HPA023153 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:6.80e-5 (favourable), Colorectal cancer:4.08e-4 (favourable), Pancreatic cancer:8.66e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 43.0 Expressed in all +GSR ENSG00000104687 Glutathione-disulfide reductase 8 30678061-30727926 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001538, CAB008632 Approved Supported Plasma membrane
Cytosol Liver cancer:3.26e-5 (unfavourable), Colorectal cancer:4.08e-5 (favourable), Renal cancer:1.80e-4 (favourable), Cervical cancer:3.37e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 79.3 Expressed in all +TNFRSF10A Apo2, CD261, DR4, TRAILR-1 ENSG00000104689 TNF receptor superfamily member 10a 8 23190452-23225126 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level HPA050958, HPA054475 Approved Supported Nucleoplasm Pancreatic cancer:1.00e-4 (unfavourable) Expressed in all Mixed lymph node: 15.9 Mixed +UBXN8 D8S2298E, REP8, UBXD6 ENSG00000104691 UBX domain protein 8 8 30732247-30767006 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017725, HPA077538 Approved Supported Nucleoplasm
Nucleoli
Endoplasmic reticulum Renal cancer:5.25e-5 (unfavourable), Colorectal cancer:6.13e-4 (favourable) Expressed in all Expressed in all ovary: 109.4 Expressed in all +PPP2CB PP2Abeta ENSG00000104695 Protein phosphatase 2 catalytic subunit beta 8 30774457-30814314 Enzymes, Predicted intracellular proteins Evidence at protein level CAB018600, HPA043236 Approved Supported Nucleoplasm Renal cancer:5.82e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 207.5 Expressed in all +ERICH1 ENSG00000104714 Glutamate rich 1 8 614746-738106 Predicted intracellular proteins Evidence at protein level HPA003725 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all Expressed in all lymph node: 24.2 Mixed +NEFM NEF3, NF-M, NFM ENSG00000104722 Neurofilament medium 8 24913012-24919098 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010900, CAB012976, HPA022845, HPA023138 Enhanced Enhanced Intermediate filaments Mixed Tissue enhanced cerebral cortex: 171.7;seminal vesicle: 42.2 adrenal gland: 28.2 Cell line enriched 22 HEK 293: 3411.6 +TUSC3 MGC13453, MRT7, N33, OST3A ENSG00000104723 Tumor suppressor candidate 3 8 15417215-15766649 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA049851, HPA049974 Approved Thyroid cancer:7.86e-4 (favourable) Expressed in all Mixed epididymis: 143.1 Mixed +ARHGEF10 Gef10, KIAA0294 ENSG00000104728 Rho guanine nucleotide exchange factor 10 8 1823976-1958641 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024649 Approved Approved Nucleoplasm Mixed Mixed testis: 15.9 Mixed +KLHDC4 DKFZp434G0522 ENSG00000104731 Kelch domain containing 4 16 87696485-87765992 Predicted intracellular proteins Evidence at protein level HPA041665 Approved Supported Nucleoli Pancreatic cancer:1.14e-4 (favourable), Urothelial cancer:1.69e-4 (favourable) Expressed in all Expressed in all lymph node: 19.0 Expressed in all +MCM4 CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21 ENSG00000104738 Minichromosome maintenance complex component 4 8 47960185-47978160 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004497, HPA004873, HPA031052 Supported Enhanced Nucleoplasm Endometrial cancer:2.84e-5 (unfavourable), Melanoma:1.15e-4 (unfavourable), Liver cancer:1.23e-4 (unfavourable), Colorectal cancer:2.19e-4 (favourable), Pancreatic cancer:2.38e-4 (unfavourable), Renal cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all testis: 78.6 Expressed in all +ADAM2 CT15, FTNB, PH-30b, PH30 ENSG00000104755 ADAM metallopeptidase domain 2 8 39743735-39838289 Predicted membrane proteins Evidence at protein level CAB022390, HPA024621, HPA026581 Enhanced Tissue enhanced Tissue enriched 284 testis: 41.9 breast: 0.1 Not detected +KCTD9 BTBD27, FLJ20038 ENSG00000104756 Potassium channel tetramerization domain containing 9 8 25427847-25458476 Predicted intracellular proteins Evidence at protein level HPA042468, HPA047902 Supported Nucleoplasm
Intermediate filaments
Cytosol Colorectal cancer:7.88e-4 (favourable) Expressed in all Expressed in all prostate: 28.1 Expressed in all +FGL1 HFREP-1 ENSG00000104760 Fibrinogen like 1 8 17864380-17910365 Plasma proteins, Predicted secreted proteins Evidence at protein level Stomach cancer:5.38e-4 (unfavourable) Tissue enriched Tissue enriched 7 liver: 1005.3 pancreas: 137.8 Group enriched 12 A549: 49.7;Hep G2: 89.4 +ASAH1 AC, ACDase, ASAH, FLJ21558, PHP32 ENSG00000104763 N-acylsphingosine amidohydrolase 1 8 18055992-18084998 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005468 Supported Renal cancer:3.08e-8 (favourable) Expressed in all Expressed in all thyroid gland: 547.6 Expressed in all +BNIP3L BNIP3a, Nix ENSG00000104765 BCL2 interacting protein 3 like 8 26382898-26505636 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level HPA015652, CAB025371 Enhanced Enhanced Nuclear speckles
Mitochondria Renal cancer:5.92e-5 (unfavourable), Thyroid cancer:3.95e-4 (unfavourable) Expressed in all Expressed in all placenta: 147.5 Expressed in all +MAN2B1 LAMAN, MANB ENSG00000104774 Mannosidase alpha class 2B member 1 19 12646511-12666742 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA041530, HPA053404 Supported Approved Nucleoplasm
Vesicles Renal cancer:1.94e-5 (unfavourable) Expressed in all Expressed in all spleen: 95.1 Expressed in all +KCNN4 hIKCa1, hKCa4, hSK4, IK, KCa3.1 ENSG00000104783 Potassium calcium-activated channel subfamily N member 4 19 43766533-43781257 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA053841, HPA059622 Approved Renal cancer:1.05e-14 (unfavourable), Urothelial cancer:1.75e-4 (favourable), Glioma:3.77e-4 (unfavourable), Pancreatic cancer:4.56e-4 (unfavourable) Expressed in all Tissue enhanced salivary gland: 73.7 stomach: 36.6 Cell line enhanced CAPAN-2: 93.3;WM-115: 264.9 +TULP2 CT65, TUBL2 ENSG00000104804 Tubby like protein 2 19 48880965-48898733 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 12 testis: 41.0 bone marrow: 3.4 Cell line enhanced BEWO: 2.5;U-266/70: 2.3;U-266/84: 2.4 +NUCB1 Calnuc, NUC ENSG00000104805 Nucleobindin 1 19 48900050-48923372 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA008176 Enhanced Supported Golgi apparatus
Microtubules Expressed in all Expressed in all parathyroid gland: 227.7 Expressed in all +DHDH HUM2DD ENSG00000104808 Dihydrodiol dehydrogenase 19 48933682-48944969 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044131 Approved Approved Nucleoplasm
Actin filaments Renal cancer:3.15e-4 (favourable), Endometrial cancer:9.91e-4 (unfavourable) Expressed in all Group enriched 5 duodenum: 10.2;kidney: 17.8;prostate: 5.1;small intestine: 18.6 testis: 2.5 Cell line enhanced SCLC-21H: 2.5 +GYS1 GSY, GYS ENSG00000104812 Glycogen synthase 1 19 48968125-48993310 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB007793, HPA041598 Enhanced Approved Microtubules
Cytosol Renal cancer:3.46e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 109.7 Expressed in all +MAP4K1 HPK1 ENSG00000104814 Mitogen-activated protein kinase kinase kinase kinase 1 19 38587641-38618882 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007419, CAB007754 Enhanced Uncertain Nucleoplasm
Plasma membrane Renal cancer:7.99e-10 (unfavourable), Cervical cancer:6.17e-5 (favourable), Head and neck cancer:3.26e-4 (favourable) Expressed in all Tissue enhanced lymph node: 37.3;spleen: 23.8;tonsil: 27.2 appendix: 19.2 Cell line enhanced Daudi: 34.0;HDLM-2: 44.1;Karpas-707: 34.0;U-266/70: 28.3;U-266/84: 27.3;U-698: 41.0 +CGB2 ENSG00000104818 Chorionic gonadotropin beta subunit 2 19 49031912-49033238 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038925, HPA038934 Supported Approved Cytosol Not detected Not detected testis: 0.7 Cell line enhanced HMC-1: 28.4;U-266/70: 9.9;U-266/84: 11.8 +ECH1 HPXEL ENSG00000104823 Enoyl-CoA hydratase 1 19 38815422-38832005 Predicted intracellular proteins Evidence at protein level HPA002907, HPA005835 Supported Approved Supported Mitochondria Stomach cancer:2.23e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 188.1 Expressed in all +HNRNPL HNRPL ENSG00000104824 Heterogeneous nuclear ribonucleoprotein L 19 38836388-38852347 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016326, HPA051748, HPA052661 Supported Enhanced Nucleoplasm Renal cancer:1.96e-11 (unfavourable), Liver cancer:3.25e-6 (unfavourable), Pancreatic cancer:9.69e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 110.4 Expressed in all +NFKBIB IKBB, TRIP9 ENSG00000104825 NFKB inhibitor beta 19 38899700-38908893 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063734 Approved Nucleoplasm
Centrosome
Cytosol Expressed in all Tissue enhanced testis: 16.6 appendix: 7.1 Expressed in all +LHB CGB4, hLHB, LSH-B ENSG00000104826 Luteinizing hormone beta polypeptide 19 49015980-49017081 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level CAB022241, CAB022707, HPA038925 Supported Approved Cytosol Pancreatic cancer:6.78e-4 (unfavourable) Mixed Tissue enhanced duodenum: 3.2;pancreas: 4.8;testis: 2.9 adrenal gland,skin,small intestine: 0.7 Mixed +CGB3 CGB ENSG00000104827 Chorionic gonadotropin beta subunit 3 19 49022869-49024333 Predicted secreted proteins Evidence at protein level CAB000042, CAB010884, HPA038925, HPA038934 Enhanced Approved Cytosol Tissue enhanced Tissue enriched 21 placenta: 14.9 testis: 0.7 Cell line enriched 23 BEWO: 65.1 +TUBB4A beta-5, DYT4, TUBB4 ENSG00000104833 Tubulin beta 4A class IVa 19 6494319-6502848 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010768, HPA043640, HPA046280 Approved Supported Microtubules Endometrial cancer:8.42e-7 (unfavourable) Group enriched Tissue enhanced adrenal gland: 137.6;cerebral cortex: 554.4 testis: 102.4 Cell line enhanced AN3-CA: 82.5;HAP1: 52.9;HEL: 69.1 +SARS2 FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS ENSG00000104835 Seryl-tRNA synthetase 2, mitochondrial 19 38915266-38930896 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA052730, HPA056957 Approved Expressed in all Expressed in all thyroid gland: 8.9 Expressed in all +KCNA7 HAK6, Kv1.7 ENSG00000104848 Potassium voltage-gated channel subfamily A member 7 19 49067418-49072941 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level Not detected Tissue enriched 37 skeletal muscle: 26.2 esophagus: 0.7 Not detected +SNRNP70 RNPU1Z, RPU1, Snp1, SNRP70, U1-70K ENSG00000104852 Small nuclear ribonucleoprotein U1 subunit 70 19 49085419-49108605 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001718, HPA042050, HPA043516 Supported Enhanced Nucleoplasm Pancreatic cancer:4.59e-5 (favourable), Urothelial cancer:5.35e-5 (favourable), Renal cancer:6.12e-5 (unfavourable) Expressed in all Expressed in all endometrium: 59.8 Expressed in all +CLPTM1 ENSG00000104853 CLPTM1, transmembrane protein 19 44954585-44993341 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA068702 Approved Nuclear membrane
Microtubule organizing center Expressed in all Expressed in all parathyroid gland: 129.9 Expressed in all +RELB REL-B ENSG00000104856 RELB proto-oncogene, NF-kB subunit 19 45001430-45038198 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB007753, HPA040506 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.99e-6 (unfavourable), Breast cancer:1.55e-4 (favourable) Expressed in all Expressed in all appendix: 25.1 Cell line enhanced HDLM-2: 73.5 +CLASRP CLASP, SFRS16, SWAP2 ENSG00000104859 CLK4 associating serine/arginine rich protein 19 45039040-45070956 Predicted intracellular proteins Evidence at protein level HPA060469, HPA062455 Approved Enhanced Nucleus Renal cancer:1.69e-8 (unfavourable), Urothelial cancer:1.02e-5 (favourable), Colorectal cancer:9.77e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 11.9 Expressed in all +LIN7B LIN-7B, MALS-2, VELI2 ENSG00000104863 Lin-7 homolog B, crumbs cell polarity complex component 19 49114324-49118460 Predicted intracellular proteins Evidence at protein level Endometrial cancer:7.00e-4 (favourable) Expressed in all Mixed cerebral cortex: 18.2 Mixed +PPP1R37 LRRC68 ENSG00000104866 Protein phosphatase 1 regulatory subunit 37 19 45091396-45148077 Predicted intracellular proteins Evidence at protein level HPA041500 Approved Approved Cytosol Urothelial cancer:2.04e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 22.3 Expressed in all +FCGRT alpha-chain, FCRN ENSG00000104870 Fc fragment of IgG receptor and transporter 19 49506816-49526333 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012122, HPA015130 Approved Expressed in all Expressed in all small intestine: 312.0 Mixed +PIH1D1 FLJ20643, NOP17 ENSG00000104872 PIH1 domain containing 1 19 49446298-49453497 Predicted intracellular proteins Evidence at protein level HPA047258 Approved Approved Cytosol Expressed in all Expressed in all fallopian tube: 64.8 Expressed in all +CKM CKMM ENSG00000104879 Creatine kinase, M-type 19 45306414-45322977 Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047859 Enhanced Group enriched Tissue enriched 17 skeletal muscle: 23798.9 heart muscle: 1418.8 Cell line enriched 6 SCLC-21H: 75.4 +ARHGEF18 KIAA0521, MGC15913, P114-RhoGEF ENSG00000104880 Rho/Rac guanine nucleotide exchange factor 18 19 7395113-7472477 Predicted intracellular proteins Evidence at protein level HPA042689, HPA071867 Approved Enhanced Cytosol Renal cancer:3.11e-5 (favourable), Head and neck cancer:4.21e-4 (favourable) Expressed in all Expressed in all spleen: 30.5 Expressed in all +PPP1R13L IASPP, RAI ENSG00000104881 Protein phosphatase 1 regulatory subunit 13 like 19 45379634-45406349 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005016, HPA041231, HPA059883 Approved Enhanced Cytosol Lung cancer:3.39e-5 (unfavourable), Ovarian cancer:5.40e-4 (unfavourable) Expressed in all Tissue enhanced skin: 191.4 esophagus: 53.8 Cell line enhanced hTCEpi: 138.6 +PEX11G ENSG00000104883 Peroxisomal biogenesis factor 11 gamma 19 7476875-7497449 Predicted membrane proteins Evidence at protein level HPA069817 Uncertain Renal cancer:1.83e-9 (favourable), Liver cancer:3.27e-4 (favourable), Endometrial cancer:3.60e-4 (favourable) Expressed in all Mixed testis: 15.6 Mixed +ERCC2 EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD ENSG00000104884 ERCC excision repair 2, TFIIH core complex helicase subunit 19 45349837-45370918 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005375, HPA038057, HPA069266 Approved Supported Nucleoplasm Pancreatic cancer:3.26e-4 (favourable) Expressed in all Expressed in all testis: 16.1 Expressed in all +DOT1L DOT1, KIAA1814, KMT4 ENSG00000104885 DOT1 like histone lysine methyltransferase 19 2164149-2232578 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA011875, HPA071217 Enhanced Nucleoplasm Endometrial cancer:1.69e-4 (favourable), Head and neck cancer:6.00e-4 (favourable) Expressed in all Tissue enriched 7 testis: 92.3 appendix,bone marrow: 14.0 Expressed in all +PLEKHJ1 FLJ10297 ENSG00000104886 Pleckstrin homology domain containing J1 19 2230084-2237704 Predicted intracellular proteins Evidence at protein level HPA048989 Approved Approved Mitochondria Renal cancer:1.10e-5 (favourable), Stomach cancer:6.99e-4 (favourable) Expressed in all Expressed in all duodenum: 107.8 Expressed in all +SLC17A7 BNPI, VGLUT1 ENSG00000104888 Solute carrier family 17 member 7 19 49429401-49442360 Predicted membrane proteins, Transporters Evidence at protein level CAB037183, HPA050458, HPA063679 Enhanced Supported Tissue enriched Tissue enriched 177 cerebral cortex: 584.4 adipose tissue: 3.3 Cell line enhanced HMC-1: 18.2;K-562: 6.2;SCLC-21H: 5.7 +RNASEH2A AGS4, RNASEHI, RNHIA, RNHL ENSG00000104889 Ribonuclease H2 subunit A 19 12802063-12813638 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042692 Enhanced Nucleus
Cytosol Renal cancer:6.29e-6 (unfavourable), Liver cancer:8.72e-5 (unfavourable), Cervical cancer:1.18e-4 (favourable), Ovarian cancer:1.22e-4 (favourable), Colorectal cancer:6.18e-4 (favourable) Expressed in all Expressed in all testis: 26.5 Expressed in all +KLC3 KLC2L, KLCt, KNS2B ENSG00000104892 Kinesin light chain 3 19 45333434-45351520 Predicted intracellular proteins Evidence at protein level HPA052797, HPA056508 Approved Approved Nucleoplasm
Actin filaments
Cytosol Endometrial cancer:1.46e-4 (unfavourable) Mixed Tissue enriched 6 skin: 63.9 esophagus: 10.0 Cell line enhanced A-431: 31.4;HaCaT: 14.3 +CD37 TSPAN26 ENSG00000104894 CD37 molecule 19 49335171-49343335 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002492, HPA032120, HPA032121 Enhanced Endometrial cancer:4.51e-4 (favourable) Expressed in all Tissue enhanced lymph node: 241.4;spleen: 208.7 appendix: 129.0 Cell line enhanced Daudi: 215.5;HMC-1: 252.2;RPMI-8226: 75.0;THP-1: 72.1 +SF3A2 Prp11, PRPF11, SAP62, SF3a66 ENSG00000104897 Splicing factor 3a subunit 2 19 2236504-2248679 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042843, HPA049439 Enhanced Approved Nucleoplasm Liver cancer:3.23e-5 (unfavourable), Renal cancer:2.07e-4 (unfavourable), Cervical cancer:7.16e-4 (favourable), Colorectal cancer:8.64e-4 (unfavourable) Expressed in all Expressed in all testis: 50.3 Expressed in all +AMH MIS ENSG00000104899 Anti-Mullerian hormone 19 2249309-2252073 Disease related genes, Predicted secreted proteins Evidence at protein level HPA066973 Approved Vesicles
Aggresome Colorectal cancer:9.21e-5 (unfavourable) Mixed Tissue enriched 6 testis: 1.6 cerebral cortex: 0.2 Cell line enhanced HEK 293: 15.7;NTERA-2: 6.5;REH: 6.4;SH-SY5Y: 8.2 +DKKL1 CT34, SGY-1 ENSG00000104901 Dickkopf like acrosomal protein 1 19 49361783-49375116 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025410, HPA047194 Enhanced Approved Vesicles Tissue enhanced Tissue enriched 149 testis: 265.5 endometrium,fallopian tube: 1.7 Cell line enhanced AF22: 5.0;AN3-CA: 8.9 +LYL1 bHLHa18 ENSG00000104903 LYL1, basic helix-loop-helix family member 19 13099033-13103161 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA075004 Approved Golgi apparatus Renal cancer:3.89e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 22.9;spleen: 20.7 appendix: 14.3 Cell line enhanced HEL: 113.5;HMC-1: 179.8;K-562: 90.4;NB-4: 82.5;REH: 87.2 +OAZ1 AZI, MGC138338, OAZ ENSG00000104904 Ornithine decarboxylase antizyme 1 19 2269509-2273490 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA009291 Uncertain Approved Vesicles
Microtubule organizing center Pancreatic cancer:4.10e-5 (favourable), Liver cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all lymph node: 268.1 Expressed in all +TRMT1 FLJ20244, TRM1 ENSG00000104907 TRNA methyltransferase 1 19 13104902-13117567 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041130, HPA041380 Approved Approved Nucleus
Plasma membrane
Cytosol Renal cancer:9.87e-7 (unfavourable) Expressed in all Expressed in all lymph node: 26.6 Expressed in all +STX10 hsyn10, SYN10 ENSG00000104915 Syntaxin 10 19 13144058-13150383 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035303, HPA056439 Approved Approved Golgi apparatus Renal cancer:1.69e-7 (unfavourable), Lung cancer:8.26e-4 (favourable) Expressed in all Expressed in all skin: 57.0 Expressed in all +RETN ADSF, FIZZ3, RETN1 ENSG00000104918 Resistin 19 7669044-7670454 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 6 bone marrow: 159.4 lung: 26.0 Group enriched 8 NB-4: 327.2;U-937: 187.7 +FCER2 CD23, CD23A, CLEC4J, FCE2 ENSG00000104921 Fc fragment of IgE receptor II 19 7688758-7702146 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002624, HPA008928 Enhanced Mixed Group enriched 7 appendix: 21.9;lymph node: 47.4;spleen: 52.6;tonsil: 38.0 adipose tissue: 5.8 Cell line enriched 16 HDLM-2: 416.1 +DMPK DM, DM1, DM1PK, DMK, MDPK, MT-PK ENSG00000104936 Dystrophia myotonica protein kinase 19 45769717-45782552 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007164, HPA008905 Enhanced Approved Vesicles
Cytosol Pancreatic cancer:9.39e-5 (favourable) Expressed in all Expressed in all smooth muscle: 97.3 Cell line enhanced RH-30: 99.0 +CLEC4M CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, LSIGN ENSG00000104938 C-type lectin domain family 4 member M 19 7763149-7769605 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB033689, CAB033691, HPA042661 Supported Not detected Group enriched 8 liver: 34.7;lymph node: 20.3;placenta: 12.4 testis: 2.9 Not detected +RSPH6A RSHL1, RSP4, RSP6, RSPH4B ENSG00000104941 Radial spoke head 6 homolog A 19 45795710-45815319 Predicted intracellular proteins Evidence at protein level HPA045382 Enhanced Tissue enriched Tissue enriched 7 testis: 30.4 thyroid gland: 4.5 Cell line enriched 11 RPMI-8226: 1.9 +TBC1D17 FLJ12168 ENSG00000104946 TBC1 domain family member 17 19 49877425-49888749 Predicted intracellular proteins Evidence at protein level HPA068119 Uncertain Pancreatic cancer:4.02e-4 (favourable), Head and neck cancer:7.18e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 29.8 Expressed in all +IL4I1 FIG1 ENSG00000104951 Interleukin 4 induced 1 19 49889654-49929539 Enzymes, Predicted secreted proteins Evidence at protein level HPA045598 Enhanced Renal cancer:1.23e-10 (unfavourable), Glioma:1.85e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 24.5;testis: 32.0 lymph node: 10.5 Cell line enhanced EFO-21: 31.1;HDLM-2: 55.9;Karpas-707: 33.8 +TLE6 FLJ14009, GRG6 ENSG00000104953 Transducin like enhancer of split 6 19 2977446-2995184 Disease related genes, Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced thyroid gland: 9.7 placenta: 6.5 Cell line enhanced BEWO: 16.5;U-266/70: 11.1 +CCDC130 MGC10471 ENSG00000104957 Coiled-coil domain containing 130 19 13731760-13763296 Predicted intracellular proteins Evidence at protein level HPA056977 Approved Approved Vesicles Head and neck cancer:7.83e-5 (favourable), Urothelial cancer:1.82e-4 (favourable), Renal cancer:1.97e-4 (unfavourable), Pancreatic cancer:2.34e-4 (favourable) Expressed in all Expressed in all spleen: 24.7 Expressed in all +PTOV1 ENSG00000104960 Prostate tumor overexpressed 1 19 49850735-49860744 Predicted intracellular proteins Evidence at protein level HPA051812, HPA075125 Approved Supported Nucleus Colorectal cancer:6.64e-4 (unfavourable), Pancreatic cancer:9.20e-4 (favourable) Expressed in all Expressed in all adrenal gland: 59.4 Expressed in all +AES GRG5, TLE5 ENSG00000104964 Amino-terminal enhancer of split 19 3052910-3063107 Predicted intracellular proteins Evidence at protein level HPA049499 Supported Nucleoplasm Endometrial cancer:3.89e-4 (favourable), Renal cancer:7.74e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 331.2 Mixed +NOVA2 ANOVA, NOVA3 ENSG00000104967 NOVA alternative splicing regulator 2 19 45933734-45973546 Predicted intracellular proteins Evidence at protein level HPA045607 Enhanced Approved Nucleoplasm
Nuclear bodies
Golgi apparatus Renal cancer:3.04e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 24.3 adipose tissue: 6.0 Cell line enhanced AF22: 10.0;HDLM-2: 10.4;HUVEC TERT2: 14.6;TIME: 21.5 +SGTA SGT ENSG00000104969 Small glutamine rich tetratricopeptide repeat containing alpha 19 2754714-2783371 Predicted intracellular proteins Evidence at protein level HPA056309 Approved Approved Nucleoplasm Endometrial cancer:1.04e-4 (favourable), Renal cancer:2.35e-4 (favourable), Cervical cancer:9.70e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 64.6 Mixed +KIR3DX1 FLJ00060, LENG12 ENSG00000104970 Killer cell immunoglobulin like receptor, three Ig domains X1 19 54532692-54545771 Predicted secreted proteins Evidence at transcript level HPA052110 Uncertain Not detected Not detected bone marrow: 0.3 Cell line enriched 6 U-266/84: 3.2 +LILRB1 CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB ENSG00000104972 Leukocyte immunoglobulin like receptor B1 19 54617158-54637528 Predicted membrane proteins Evidence at transcript level Renal cancer:3.08e-6 (unfavourable) Mixed Tissue enhanced appendix: 8.6;lymph node: 6.2;spleen: 9.9 smooth muscle: 3.7 Group enriched 17 Daudi: 4.0;THP-1: 1.9 +MED25 ACID1, ARC92, DKFZp434K0512, TCBAP0758 ENSG00000104973 Mediator complex subunit 25 19 49818279-49838816 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA068802 Supported Nucleoplasm Head and neck cancer:9.85e-4 (favourable) Expressed in all Expressed in all testis: 111.2 Expressed in all +LILRA1 CD85i, LIR-6, LIR6 ENSG00000104974 Leukocyte immunoglobulin like receptor A1 19 54593582-54602090 CD markers, Predicted membrane proteins Evidence at transcript level Mixed Not detected appendix: 0.8 Not detected +SNAPC2 PTFdelta, SNAP45 ENSG00000104976 Small nuclear RNA activating complex polypeptide 2 19 7920316-7923250 Predicted intracellular proteins Evidence at protein level HPA049843, HPA077597 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:4.89e-5 (unfavourable) Expressed in all Expressed in all endometrium: 30.1 Expressed in all +C19orf53 HSPC023, LYDG10 ENSG00000104979 Chromosome 19 open reading frame 53 19 13774168-13778462 Predicted intracellular proteins Evidence at protein level HPA059928, HPA061291 Approved Supported Nucleus
Nucleoli Expressed in all Expressed in all fallopian tube: 116.9 Expressed in all +TIMM44 TIM44 ENSG00000104980 Translocase of inner mitochondrial membrane 44 19 7926718-7943920 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043052 Supported Enhanced Mitochondria Expressed in all Expressed in all heart muscle: 19.1 Expressed in all +CCDC61 ENSG00000104983 Coiled-coil domain containing 61 19 45995461-46021318 Predicted intracellular proteins Evidence at protein level HPA040325, HPA061548 Uncertain Approved Nucleus Expressed in all Expressed in all testis: 31.1 Expressed in all +IL27RA CRL1, IL-27R, TCCR, WSX-1, WSX1, zcytor1 ENSG00000104998 Interleukin 27 receptor subunit alpha 19 14031748-14053216 Predicted membrane proteins Evidence at protein level Renal cancer:2.58e-10 (unfavourable), Breast cancer:1.74e-6 (favourable) Expressed in all Mixed tonsil: 30.4 Mixed +ASF1B FLJ10604 ENSG00000105011 Anti-silencing function 1B histone chaperone 19 14119509-14136956 Predicted intracellular proteins Evidence at protein level HPA054036 Supported Nucleoplasm Renal cancer:2.22e-16 (unfavourable), Cervical cancer:4.45e-5 (favourable), Pancreatic cancer:1.98e-4 (unfavourable), Liver cancer:2.03e-4 (unfavourable), Stomach cancer:2.49e-4 (favourable) Expressed in all Tissue enhanced testis: 37.2 lymph node: 24.0 Mixed +TNNT1 ANM, FLJ98147, MGC104241, NEM5, STNT, TNT, TNTS ENSG00000105048 Troponin T1, slow skeletal type 19 55132794-55149354 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015168, HPA058448 Enhanced Approved Nucleus
Golgi apparatus
Cytosol Renal cancer:0.00e+0 (unfavourable), Pancreatic cancer:2.53e-4 (unfavourable), Colorectal cancer:4.66e-4 (unfavourable), Endometrial cancer:4.66e-4 (unfavourable) Expressed in all Tissue enriched 12 skeletal muscle: 7568.7 esophagus: 632.9 Cell line enhanced HMC-1: 728.7;RH-30: 606.8 +VRK3 ENSG00000105053 Vaccinia related kinase 3 19 49976467-50025946 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056489 Approved Supported Nucleus
Vesicles Renal cancer:1.83e-4 (favourable), Urothelial cancer:5.66e-4 (favourable) Expressed in all Expressed in all testis: 168.6 Expressed in all +FAM32A DKFZP586O0120, OTAG-12 ENSG00000105058 Family with sequence similarity 32 member A 19 16185380-16192046 Predicted intracellular proteins Evidence at protein level HPA051712 Approved Supported Nucleus
Nucleoli Expressed in all Expressed in all placenta: 89.0 Expressed in all +PPP6R1 KIAA1115, SAP190, SAPS1 ENSG00000105063 Protein phosphatase 6 regulatory subunit 1 19 55229780-55258995 Predicted intracellular proteins Evidence at protein level HPA043989, HPA063681 Approved Enhanced Cytosol Liver cancer:3.82e-6 (unfavourable) Expressed in all Expressed in all testis: 117.3 Expressed in all +C19orf44 FLJ21742 ENSG00000105072 Chromosome 19 open reading frame 44 19 16496311-16521352 Predicted intracellular proteins Evidence at protein level HPA041683, HPA049414 Uncertain Approved Nucleus
Nuclear bodies Expressed in all Mixed testis: 20.2 Mixed +MED26 CRSP7, CRSP70 ENSG00000105085 Mediator complex subunit 26 19 16574907-16629062 Predicted intracellular proteins Evidence at protein level HPA057997, HPA071835 Enhanced Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:5.50e-5 (unfavourable), Cervical cancer:2.46e-4 (favourable) Expressed in all Tissue enriched 6 testis: 42.0 bone marrow: 6.8 Expressed in all +OLFM2 NOE2, OlfC ENSG00000105088 Olfactomedin 2 19 9853718-9936552 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049961, HPA057771 Uncertain Approved Nucleoplasm Renal cancer:2.21e-4 (unfavourable), Colorectal cancer:3.05e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 124.0;skin: 111.2 adipose tissue: 36.8 Cell line enhanced AN3-CA: 23.7;SH-SY5Y: 25.7;U-2 OS: 30.2;WM-115: 25.2 +RASAL3 FLJ21438 ENSG00000105122 RAS protein activator like 3 19 15451624-15464571 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA043417 Enhanced Renal cancer:1.16e-6 (unfavourable), Endometrial cancer:3.58e-5 (favourable), Head and neck cancer:3.07e-4 (favourable), Cervical cancer:8.75e-4 (favourable) Expressed in all Tissue enhanced lymph node: 37.5 spleen: 24.6 Cell line enhanced HDLM-2: 28.2;HEL: 22.6;HMC-1: 40.9;Karpas-707: 37.6;TIME: 28.9;U-937: 26.4 +AKAP8 AKAP95, DKFZp586B1222 ENSG00000105127 A-kinase anchoring protein 8 19 15353385-15379798 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004776 Supported Supported Nucleoplasm Expressed in all Expressed in all bone marrow: 13.1 Expressed in all +EPHX3 ABHD9, FLJ22408 ENSG00000105131 Epoxide hydrolase 3 19 15226919-15233435 Predicted secreted proteins Evidence at transcript level HPA012842 Uncertain Head and neck cancer:2.27e-5 (favourable) Tissue enhanced Group enriched 7 esophagus: 35.1;skin: 62.8;tonsil: 24.3 parathyroid gland: 5.5 Cell line enhanced EFO-21: 2.3;NTERA-2: 2.3;SCLC-21H: 1.2 +ILVBL 209L8, AHAS, FLJ39061, HACL1L, ILV2H, MGC1269, MGC19535 ENSG00000105135 IlvB acetolactate synthase like 19 15114984-15125785 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA067682 Approved Approved Golgi apparatus
Vesicles Renal cancer:1.91e-8 (favourable), Endometrial cancer:1.52e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 80.2 Expressed in all +ZNF419 ZAPHIR, ZNF419A ENSG00000105136 Zinc finger protein 419 19 57487711-57496097 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA003152, HPA003274 Uncertain Supported Nucleus
Nucleoli fibrillar center Urothelial cancer:2.53e-5 (favourable), Prostate cancer:6.47e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 16.2 Mixed +SYDE1 7h3, FLJ13511, SYD1 ENSG00000105137 Synapse defective Rho GTPase homolog 1 19 15107403-15114988 Predicted intracellular proteins Evidence at protein level HPA013328 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:5.63e-7 (unfavourable), Urothelial cancer:8.27e-4 (unfavourable) Expressed in all Mixed placenta: 21.8 Cell line enhanced U-138 MG: 104.0 +CASP14 MGC119078, MGC119079, MICE ENSG00000105141 Caspase 14 19 15049384-15058293 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB010059, HPA027062 Enhanced Approved Nucleus
Mitochondria
Cytosol Pancreatic cancer:5.96e-4 (unfavourable), Lung cancer:7.59e-4 (unfavourable) Tissue enhanced Tissue enriched 55 skin: 558.6 breast: 10.1 Cell line enriched 6 hTCEpi: 34.2 +SLC1A6 EAAT4 ENSG00000105143 Solute carrier family 1 member 6 19 14950034-15022990 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041505, HPA044066 Enhanced Uncertain Intermediate filaments Urothelial cancer:6.88e-6 (unfavourable) Tissue enriched Group enriched 5 cerebral cortex: 16.2;skin: 8.9;testis: 36.9 epididymis: 3.7 Group enriched 5 HAP1: 7.6;NTERA-2: 6.0;U-698: 19.3 +AURKC ARK3, AurC, STK13 ENSG00000105146 Aurora kinase C 19 57230802-57235548 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA034859 Uncertain Mixed Tissue enriched 11 testis: 73.7 spleen: 6.9 Cell line enriched 7 NTERA-2: 39.0 +POP4 RPP29 ENSG00000105171 POP4 homolog, ribonuclease P/MRP subunit 19 29604017-29617237 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042748 Approved Liver cancer:3.31e-4 (unfavourable) Expressed in all Expressed in all testis: 15.2 Expressed in all +CCNE1 CCNE ENSG00000105173 Cyclin E1 19 29811898-29824308 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB000308, CAB016682, HPA018169 Approved Enhanced Nucleoplasm Endometrial cancer:6.35e-6 (unfavourable), Liver cancer:3.89e-5 (unfavourable), Ovarian cancer:2.97e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 44.6 testis: 22.5 Expressed in all +URI1 C19orf2, FLJ10575, NNX3, PPP1R19, RMP, URI ENSG00000105176 URI1, prefoldin like chaperone 19 29923644-30016608 Predicted intracellular proteins Evidence at protein level HPA071709 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:1.12e-4 (unfavourable) Expressed in all Expressed in all testis: 94.9 Expressed in all +PDCD5 MGC9294, TFAR19 ENSG00000105185 Programmed cell death 5 19 32581068-32587452 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018471 Enhanced Approved Nucleus
Cytosol Renal cancer:0.00e+0 (unfavourable), Endometrial cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all testis: 175.1 Expressed in all +ANKRD27 DKFZp434L0718, FLJ00040, VARP ENSG00000105186 Ankyrin repeat domain 27 19 32597007-32676597 Predicted intracellular proteins Evidence at protein level HPA042769 Approved Enhanced Cytosol Liver cancer:1.21e-5 (unfavourable), Endometrial cancer:8.68e-4 (unfavourable) Expressed in all Expressed in all testis: 32.4 Expressed in all +RPS16 S16 ENSG00000105193 Ribosomal protein S16 19 39433207-39435948 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA064222 Approved Enhanced Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 3703.7 Expressed in all +TIMM50 TIM50L ENSG00000105197 Translocase of inner mitochondrial membrane 50 19 39480412-39493785 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048843, HPA056448 Enhanced Supported Nucleoplasm
Mitochondria Expressed in all Expressed in all testis: 80.4 Expressed in all +LGALS13 PLAC8, PP13 ENSG00000105198 Galectin 13 19 39602501-39607476 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 34 placenta: 16.6 testis: 0.4 Not detected +FBL FIB, FLRN, RNU3IP1 ENSG00000105202 Fibrillarin 19 39834458-39846414 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001514, HPA049546 Supported Enhanced Nucleoli fibrillar center Renal cancer:4.52e-6 (unfavourable), Liver cancer:1.32e-4 (unfavourable), Breast cancer:1.65e-4 (favourable) Expressed in all Expressed in all ovary: 212.6 Expressed in all +DYRK1B MIRK ENSG00000105204 Dual specificity tyrosine phosphorylation regulated kinase 1B 19 39825350-39834201 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028522, HPA028786 Uncertain Approved Nucleus Renal cancer:8.83e-4 (favourable) Expressed in all Tissue enhanced skeletal muscle: 37.4 testis: 33.6 Cell line enhanced SCLC-21H: 15.0;SH-SY5Y: 15.3 +CLC Gal-10, LGALS10, MGC149659 ENSG00000105205 Charcot-Leyden crystal galectin 19 39731250-39738028 Predicted intracellular proteins Evidence at protein level HPA041751 Enhanced Tissue enhanced Tissue enriched 5 bone marrow: 285.9 urinary bladder: 55.3 Cell line enriched 14 HMC-1: 6580.2 +CNTD2 CCNP, FLJ13265 ENSG00000105219 Cyclin N-terminal domain containing 2 19 40222208-40226690 Predicted intracellular proteins Evidence at transcript level HPA045615 Uncertain Mixed Not detected adipose tissue: 0.9 Cell line enhanced SCLC-21H: 2.5 +GPI AMF, NLK ENSG00000105220 Glucose-6-phosphate isomerase 19 34359480-34402156 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB018655, HPA024305, CAB040563, HPA052171 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 314.1 Expressed in all +AKT2 ENSG00000105221 AKT serine/threonine kinase 2 19 40230317-40285536 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004204, HPA064521 Uncertain Supported Nucleus
Vesicles
Cytosol Endometrial cancer:1.05e-6 (unfavourable), Prostate cancer:4.74e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 170.1 Expressed in all +PLD3 HU-K4 ENSG00000105223 Phospholipase D family member 3 19 40348456-40380439 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012800, CAB020812 Approved Renal cancer:2.21e-4 (favourable), Pancreatic cancer:6.44e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 494.9 Expressed in all +PRX KIAA1620 ENSG00000105227 Periaxin 19 40393768-40413366 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001868 Enhanced Approved Golgi apparatus
Vesicles
Plasma membrane Expressed in all Tissue enhanced lung: 28.8 parathyroid gland: 9.4 Mixed +PIAS4 FLJ12419, Piasg, PIASY, ZMIZ6 ENSG00000105229 Protein inhibitor of activated STAT 4 19 4007646-4039386 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010598 Approved Approved Nucleoplasm Endometrial cancer:1.18e-5 (favourable), Pancreatic cancer:7.04e-4 (favourable) Expressed in all Expressed in all testis: 29.3 Expressed in all +NUMBL CAG3A, CTG3a, NUMB-R, NUMBLIKE, NUMBR, TNRC23 ENSG00000105245 NUMB like, endocytic adaptor protein 19 40665905-40690972 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058251, HPA058380 Approved Renal cancer:7.55e-15 (unfavourable), Ovarian cancer:1.52e-4 (unfavourable), Colorectal cancer:3.49e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 41.7 Expressed in all +EBI3 IL27B, IL35B ENSG00000105246 Epstein-Barr virus induced 3 19 4229498-4237531 Predicted secreted proteins Evidence at protein level HPA046635 Enhanced Renal cancer:1.04e-8 (unfavourable) Expressed in all Tissue enriched 8 placenta: 209.2 spleen: 26.1 Cell line enriched 13 HDLM-2: 197.3 +CCDC94 FLJ10374 ENSG00000105248 Coiled-coil domain containing 94 19 4247079-4269090 Predicted intracellular proteins Evidence at protein level HPA043606, HPA055675 Approved Supported Nucleoplasm Renal cancer:6.32e-4 (favourable), Stomach cancer:8.04e-4 (favourable) Expressed in all Expressed in all bone marrow: 28.0 Expressed in all +SHD ENSG00000105251 Src homology 2 domain containing transforming protein D 19 4278601-4290724 Predicted intracellular proteins Evidence at protein level HPA017955 Uncertain Uncertain Microtubule organizing center
Cytosol Tissue enhanced Tissue enriched 6 cerebral cortex: 22.1 heart muscle: 3.8 Group enriched 57 RH-30: 51.7;SH-SY5Y: 181.9 +TBCB CG22, CKAP1, CKAPI ENSG00000105254 Tubulin folding cofactor B 19 36114289-36125947 Predicted intracellular proteins Evidence at protein level HPA041428, HPA041722 Approved Supported Cytosol Liver cancer:2.09e-4 (unfavourable), Pancreatic cancer:3.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 249.9 Expressed in all +FSD1 MGC3213, MIR1 ENSG00000105255 Fibronectin type III and SPRY domain containing 1 19 4304600-4323843 Predicted intracellular proteins Evidence at protein level HPA043141 Supported Endometrial cancer:1.61e-4 (unfavourable) Group enriched Group enriched 12 cerebral cortex: 25.4;testis: 9.1 lymph node: 1.4 Cell line enhanced SCLC-21H: 65.0;SH-SY5Y: 60.9 +POLR2I hRPB14.5, RPB9 ENSG00000105258 RNA polymerase II subunit I 19 36113710-36115346 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA035632, HPA045156 Uncertain Enhanced Nucleoplasm Expressed in all Expressed in all cerebral cortex: 18.4 Expressed in all +OVOL3 HOVO3 ENSG00000105261 Ovo like zinc finger 3 19 36111151-36113711 Predicted intracellular proteins, Transcription factors Evidence at transcript level Not detected Group enriched 5 skin: 1.0;testis: 2.8 appendix: 0.3 Cell line enhanced U-266/84: 2.1 +CLIP3 CLIPR-59, RSNL1 ENSG00000105270 CAP-Gly domain containing linker protein 3 19 36014660-36033343 Predicted intracellular proteins Evidence at protein level Renal cancer:1.56e-10 (unfavourable), Pancreatic cancer:2.80e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 247.6 smooth muscle: 56.2 Cell line enhanced ASC TERT1: 58.0;HSkMC: 67.3 +ZFR2 KIAA1086 ENSG00000105278 Zinc finger RNA binding protein 2 19 3804024-3869032 Predicted intracellular proteins Evidence at protein level HPA043275, HPA055678 Uncertain Uncertain Nucleoplasm Tissue enhanced Group enriched 9 adrenal gland: 3.8;cerebral cortex: 12.7;testis: 19.0 fallopian tube: 1.3 Group enriched 12 HMC-1: 24.1;NTERA-2: 47.6;SiHa: 15.2 +SLC1A5 AAAT, ASCT2, M7V1, RDRC ENSG00000105281 Solute carrier family 1 member 5 19 46774883-46788594 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA035239, HPA035240 Enhanced Enhanced Plasma membrane Liver cancer:1.66e-8 (unfavourable), Renal cancer:1.18e-7 (unfavourable) Expressed in all Expressed in all epididymis: 119.2 Expressed in all +PRKD2 DKFZP586E0820, HSPC187, PKD2 ENSG00000105287 Protein kinase D2 19 46674275-46717127 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021490, HPA056727 Enhanced Supported Nucleoplasm
Cytosol Urothelial cancer:9.15e-4 (favourable) Expressed in all Expressed in all spleen: 60.3 Expressed in all +TJP3 ZO-3 ENSG00000105289 Tight junction protein 3 19 3708109-3750813 Predicted intracellular proteins Evidence at protein level CAB013244, HPA046863, HPA053337 Enhanced Enhanced Nucleoplasm
Cell Junctions Renal cancer:9.36e-8 (favourable), Endometrial cancer:1.83e-6 (favourable), Head and neck cancer:9.52e-4 (favourable) Mixed Tissue enhanced duodenum: 41.5;small intestine: 41.3 colon: 30.6 Cell line enhanced BEWO: 42.4;CAPAN-2: 39.5;SK-BR-3: 19.4;T-47d: 51.5 +APLP1 APLP ENSG00000105290 Amyloid beta precursor like protein 1 19 35867899-35879791 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028970, HPA028971 Enhanced Urothelial cancer:2.65e-5 (unfavourable), Endometrial cancer:3.87e-4 (unfavourable) Tissue enhanced Tissue enriched 13 cerebral cortex: 440.4 adrenal gland: 34.5 Cell line enhanced AN3-CA: 137.3;SCLC-21H: 100.6;SH-SY5Y: 91.5 +CACTIN C19orf29, cactin, fSAPc, NY-REN-24 ENSG00000105298 Cactin, spliceosome C complex subunit 19 3610641-3626815 Predicted intracellular proteins Evidence at protein level HPA042504, HPA042548 Approved Supported Nucleoplasm
Nuclear speckles
Cytosol Endometrial cancer:3.69e-5 (favourable) Expressed in all Expressed in all spleen: 14.4 Expressed in all +CCDC9 DKFZP586M1019 ENSG00000105321 Coiled-coil domain containing 9 19 47255980-47271953 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045624, HPA072007 Approved Approved Cytosol Expressed in all Expressed in all testis: 30.3 Expressed in all +HNRNPUL1 E1B-AP5, E1BAP5, FLJ12944, HNRPUL1 ENSG00000105323 Heterogeneous nuclear ribonucleoprotein U like 1 19 41262496-41307598 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046290, CAB046477, HPA049475 Enhanced Enhanced Nucleoplasm Endometrial cancer:1.84e-5 (unfavourable) Expressed in all Expressed in all testis: 150.1 Expressed in all +FZR1 CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1, KIAA1242 ENSG00000105325 Fizzy and cell division cycle 20 related 1 19 3506273-3538330 Predicted intracellular proteins Evidence at protein level HPA043536 Approved Supported Nucleoplasm
Nuclear membrane Cervical cancer:1.75e-4 (favourable), Endometrial cancer:2.57e-4 (favourable) Expressed in all Expressed in all testis: 33.1 Expressed in all +BBC3 JFY1, PUMA ENSG00000105327 BCL2 binding component 3 19 47220822-47232766 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007752, HPA070403 Approved Approved Cytosol Urothelial cancer:2.62e-5 (favourable), Endometrial cancer:1.31e-4 (favourable) Expressed in all Mixed cerebral cortex,skin: 4.7 Mixed +TGFB1 CED, DPD1, TGFB, TGFbeta ENSG00000105329 Transforming growth factor beta 1 19 41301587-41353911 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000361, CAB073543 Approved Uncertain Cytosol Renal cancer:1.19e-8 (unfavourable), Head and neck cancer:3.38e-4 (unfavourable) Expressed in all Expressed in all spleen: 83.5 Mixed +DENND3 KIAA0870 ENSG00000105339 DENN domain containing 3 8 141117278-141195808 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024491, HPA041668 Approved Approved Vesicles
Cytosol Expressed in all Mixed bone marrow: 68.5 Cell line enhanced HDLM-2: 60.7;HeLa: 52.8 +ATP5SL FLJ10241 ENSG00000105341 ATP5S like 19 41431318-41440717 Predicted intracellular proteins Evidence at protein level HPA041427 Approved Approved Mitochondria Renal cancer:4.07e-5 (favourable), Liver cancer:1.77e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 50.5 Expressed in all +CEACAM4 CGM7 ENSG00000105352 Carcinoembryonic antigen related cell adhesion molecule 4 19 41618971-41627074 Predicted membrane proteins Evidence at protein level Mixed Group enriched 6 appendix: 6.7;bone marrow: 13.9;spleen: 9.0 adipose tissue: 1.7 Cell line enriched 7 U-937: 3.2 +PLIN3 M6PRBP1, PP17, TIP47 ENSG00000105355 Perilipin 3 19 4838341-4867768 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006427, HPA066538 Uncertain Enhanced Lipid droplets
Cytosol Renal cancer:9.15e-7 (unfavourable), Lung cancer:7.67e-6 (unfavourable), Liver cancer:3.27e-5 (unfavourable), Endometrial cancer:2.62e-4 (favourable) Expressed in all Expressed in all esophagus: 115.7 Expressed in all +MYH14 DFNA4, FLJ13881, KIAA2034, MHC16, MYH17 ENSG00000105357 Myosin heavy chain 14 19 50188186-50310545 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062391, HPA067889, HPA070260 Enhanced Approved Nucleoplasm Renal cancer:3.97e-8 (favourable), Stomach cancer:7.83e-4 (favourable) Expressed in all Mixed small intestine: 83.5 Cell line enhanced CAPAN-2: 50.4;HaCaT: 91.2;MCF7: 44.9;RT4: 116.8 +MRPL4 CGI-28 ENSG00000105364 Mitochondrial ribosomal protein L4 19 10251901-10260045 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA051261 Approved Supported Nucleus
Nucleoli
Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all cerebral cortex: 38.9 Expressed in all +SIGLEC8 MGC59785, SAF2, SIGLEC-8, SIGLEC8L ENSG00000105366 Sialic acid binding Ig like lectin 8 19 51450847-51458456 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA012556 Approved Uncertain Cytosol Tissue enhanced Mixed lymph node: 7.5 Cell line enriched 60 HMC-1: 129.9 +CD79A IGA, MB-1 ENSG00000105369 CD79a molecule 19 41877120-41881372 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000019 Enhanced Head and neck cancer:1.18e-5 (favourable), Renal cancer:2.15e-5 (unfavourable), Breast cancer:8.45e-5 (favourable) Mixed Group enriched 6 appendix: 263.8;lymph node: 515.1;spleen: 317.9;tonsil: 423.1 stomach: 63.3 Group enriched 23 Daudi: 1084.6;REH: 432.6;U-698: 905.8 +LIM2 MP17, MP19 ENSG00000105370 Lens intrinsic membrane protein 2 19 51379909-51387960 Disease related genes, Predicted membrane proteins Evidence at protein level Tissue enriched Not detected testis: 0.4 Not detected +ICAM4 CD242, LW ENSG00000105371 Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 19 10286967-10288522 Blood group antigen proteins, CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enhanced bone marrow: 8.7;lung: 14.5 epididymis: 2.9 Cell line enhanced HEL: 67.4;K-562: 35.3;NB-4: 20.5 +RPS19 DBA, S19 ENSG00000105372 Ribosomal protein S19 19 41859918-41872926 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA063217 Supported Nucleoplasm Renal cancer:2.32e-8 (unfavourable) Expressed in all Expressed in all ovary: 3251.4 Expressed in all +GLTSCR2 PICT-1 ENSG00000105373 Glioma tumor suppressor candidate region gene 2 19 47745522-47757058 Predicted intracellular proteins Evidence at protein level HPA018999, HPA049600 Approved Enhanced Nucleoli Endometrial cancer:2.35e-4 (favourable) Expressed in all Expressed in all ovary: 534.2 Expressed in all +NKG7 GIG1, GMP-17 ENSG00000105374 Natural killer cell granule protein 7 19 51371606-51372715 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA071454 Approved Vesicles Renal cancer:3.32e-6 (unfavourable), Endometrial cancer:7.42e-6 (favourable) Expressed in all Tissue enhanced bone marrow: 351.3;spleen: 151.2 lymph node: 122.0 Cell line enhanced NB-4: 109.5;THP-1: 34.5;U-937: 34.9 +ICAM5 TLCN, TLN ENSG00000105376 Intercellular adhesion molecule 5 19 10289981-10296778 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008943, HPA009083, CAB025178 Enhanced Tissue enhanced Tissue enriched 10 cerebral cortex: 21.6 lung: 2.0 Cell line enhanced HEL: 14.8;K-562: 12.0;RPMI-8226: 10.5;U-266/70: 13.3;U-87 MG: 10.1 +ETFB ENSG00000105379 Electron transfer flavoprotein beta subunit 19 51345169-51366418 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018910, HPA018921, HPA018923 Supported Enhanced Mitochondria Renal cancer:6.45e-5 (favourable), Cervical cancer:6.45e-4 (favourable) Expressed in all Expressed in all liver: 172.1 Expressed in all +CD33 FLJ00391, p67, SIGLEC-3, SIGLEC3 ENSG00000105383 CD33 molecule 19 51225064-51243860 CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011442, HPA035832, HPA064807 Approved Supported Nucleus
Plasma membrane Mixed Tissue enhanced spleen: 33.1 bone marrow: 20.9 Cell line enhanced HEL: 77.8;HL-60: 92.6;HMC-1: 72.6;RPMI-8226: 43.3;THP-1: 45.3;U-937: 66.2 +CEACAM5 CD66e, CEA ENSG00000105388 Carcinoembryonic antigen related cell adhesion molecule 5 19 41708585-41729798 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000021, CAB000022, HPA011041, HPA019758 Enhanced Supported Plasma membrane Tissue enhanced Tissue enhanced colon: 1012.7;rectum: 1086.0 appendix: 257.7 Cell line enriched 6 HaCaT: 11.8 +CRX CORD2, CRD, LCA7, OTX3 ENSG00000105392 Cone-rod homeobox 19 47819779-47843330 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036762, HPA036763 Enhanced Not detected Not detected testis: 0.3 Not detected +BABAM1 C19orf62, FLJ20571, HSPC142, MERIT40, NBA1 ENSG00000105393 BRISC and BRCA1 A complex member 1 19 17267350-17281249 Predicted intracellular proteins Evidence at protein level HPA054386, HPA068786 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all Expressed in all cerebral cortex: 84.2 Expressed in all +TYK2 JTK1 ENSG00000105397 Tyrosine kinase 2 19 10350529-10380676 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005157 Uncertain Supported Cytosol Head and neck cancer:1.05e-5 (favourable), Pancreatic cancer:1.02e-4 (favourable), Urothelial cancer:4.16e-4 (favourable), Renal cancer:4.43e-4 (unfavourable), Endometrial cancer:9.62e-4 (favourable) Expressed in all Expressed in all spleen: 68.2 Expressed in all +SULT2A1 DHEA-ST, STD ENSG00000105398 Sulfotransferase family 2A member 1 19 47870466-47886397 Enzymes, Predicted intracellular proteins Evidence at protein level CAB018755, HPA041487, HPA063633 Enhanced Supported Cytosol Tissue enriched Tissue enhanced adrenal gland: 189.9;liver: 514.2 small intestine: 91.1 Group enriched 30 Hep G2: 25.8;RT4: 20.3 +CDC37 P50CDC37 ENSG00000105401 Cell division cycle 37 19 10391134-10420121 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA003928, CAB004214 Supported Enhanced Cytosol Stomach cancer:2.33e-4 (favourable) Expressed in all Expressed in all appendix: 110.5 Expressed in all +NAPA ENSG00000105402 NSF attachment protein alpha 19 47487637-47515240 Predicted intracellular proteins Evidence at protein level CAB010100, HPA046149, HPA050196 Approved Uncertain Cytosol Renal cancer:4.26e-9 (favourable) Expressed in all Expressed in all prostate: 157.4 Expressed in all +RABAC1 PRA1, PRAF1, YIP3 ENSG00000105404 Rab acceptor 1 19 41956681-41959390 Predicted membrane proteins, Transporters Evidence at protein level CAB019320, HPA029171 Enhanced Approved Nuclear membrane
Nucleoli fibrillar center Expressed in all Expressed in all cerebral cortex: 107.2 Expressed in all +ATP1A3 DYT12 ENSG00000105409 ATPase Na+/K+ transporting subunit alpha 3 19 41966582-41997497 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB033630, HPA045367, HPA056446 Enhanced Renal cancer:3.02e-6 (unfavourable), Pancreatic cancer:6.15e-5 (favourable), Ovarian cancer:3.44e-4 (unfavourable) Group enriched Tissue enhanced cerebral cortex: 378.4;heart muscle: 86.0 testis: 54.5 Cell line enhanced Daudi: 39.5;SCLC-21H: 148.3;SH-SY5Y: 57.8 +MEIS3 DKFZp547H236, MRG2 ENSG00000105419 Meis homeobox 3 19 47403124-47419523 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA046699 Uncertain Approved Nucleoplasm Renal cancer:1.78e-6 (unfavourable) Mixed Tissue enhanced endometrium: 82.4 cerebral cortex: 64.8 Cell line enhanced AF22: 74.7 +PTPRS ENSG00000105426 Protein tyrosine phosphatase, receptor type S 19 5158495-5340803 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054747 Approved Plasma membrane
Cytosol Pancreatic cancer:1.07e-4 (favourable), Renal cancer:1.70e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 70.7 Cell line enhanced AN3-CA: 112.7;HaCaT: 110.4 +CNFN PLAC8L2 ENSG00000105427 Cornifelin 19 42387019-42390287 Predicted intracellular proteins Evidence at protein level HPA049073, HPA053997 Enhanced Approved Microtubules
Cytokinetic bridge Thyroid cancer:4.02e-5 (favourable) Expressed in all Group enriched 32 esophagus: 1158.0;skin: 272.5;tonsil: 260.7 breast: 17.6 Cell line enhanced A549: 17.1;HEK 293: 24.4 +ZNRF4 RNF204, spzn, Ssrzf1 ENSG00000105428 Zinc and ring finger 4 19 5455431-5456856 Enzymes, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 494 testis: 49.3 all non-specific tissues: 0.0 Not detected +MEGF8 C19orf49, EGFL4, FLJ22365, SBP1 ENSG00000105429 Multiple EGF like domains 8 19 42325609-42378769 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049248 Approved Renal cancer:2.17e-7 (favourable), Pancreatic cancer:6.03e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 38.0 Expressed in all +KDELR1 ERD2, ERD2.1, HDEL ENSG00000105438 KDEL endoplasmic reticulum protein retention receptor 1 19 48382570-48391553 Predicted membrane proteins, Transporters Evidence at protein level CAB017455 Approved Supported Golgi apparatus
Vesicles Liver cancer:1.61e-4 (unfavourable), Head and neck cancer:3.49e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 264.3 Expressed in all +CYTH2 ARNO, CTS18.1, cytohesin-2, PSCD2, PSCD2L, Sec7p-L, Sec7p-like ENSG00000105443 Cytohesin 2 19 48469032-48482314 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB014872, HPA060662 Uncertain Supported Golgi apparatus
Plasma membrane
Cytosol Liver cancer:1.19e-4 (unfavourable), Urothelial cancer:3.21e-4 (favourable) Expressed in all Mixed testis: 31.2 Expressed in all +GRWD1 GRWD, RRB1, WDR28 ENSG00000105447 Glutamate rich WD repeat containing 1 19 48445773-48457022 Predicted intracellular proteins Evidence at protein level HPA042643, HPA055680 Approved Supported Nucleus
Nucleoli Liver cancer:2.16e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 20.2 Expressed in all +GRIN2D EB11, GluN2D, NMDAR2D, NR2D ENSG00000105464 Glutamate ionotropic receptor NMDA type subunit 2D 19 48394875-48444931 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 2.3 placenta: 1.3 Cell line enhanced A549: 16.7;HMC-1: 27.0 +SYNGR4 ENSG00000105467 Synaptogyrin 4 19 48364395-48376376 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030075, HPA059286 Enhanced Approved Golgi apparatus Mixed Tissue enriched 10 testis: 46.8 parathyroid gland: 4.5 Group enriched 6 A549: 9.0;SCLC-21H: 28.5 +CLEC11A CLECSF3, LSLCL, P47, SCGF ENSG00000105472 C-type lectin domain family 11 member A 19 50723329-50725718 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA042690 Approved Approved Centrosome Renal cancer:1.02e-5 (unfavourable), Endometrial cancer:6.91e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 81.5 cervix, uterine: 18.6 Cell line enhanced HEL: 313.4;HMC-1: 544.7;NB-4: 546.3;THP-1: 465.7;U-937: 280.7 +CCDC114 CILD20, FLJ32926 ENSG00000105479 Coiled-coil domain containing 114 19 48296457-48321894 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042524 Approved Tissue enhanced Group enriched 5 fallopian tube: 6.3;testis: 5.7 lung: 1.1 Cell line enhanced U-266/70: 1.0 +CARD8 CARDINAL, Dakar, KIAA0955, NDPP, TUCAN ENSG00000105483 Caspase recruitment domain family member 8 19 48180770-48255946 Predicted intracellular proteins Evidence at protein level HPA042071, HPA043513 Supported Enhanced Nucleoplasm
Cytosol Renal cancer:1.63e-8 (unfavourable), Urothelial cancer:1.72e-5 (favourable) Expressed in all Expressed in all spleen: 49.1 Expressed in all +LIG1 ENSG00000105486 DNA ligase 1 19 48115445-48170603 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037015, HPA041431, HPA048071 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:5.75e-5 (unfavourable) Expressed in all Mixed bone marrow: 20.9 Mixed +SIGLEC6 CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6 ENSG00000105492 Sialic acid binding Ig like lectin 6 19 51519525-51531856 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA009084, HPA018198 Enhanced Tissue enhanced Tissue enriched 25 placenta: 147.9 lung: 6.0 Cell line enriched 7 HMC-1: 401.5 +ZNF175 OTK18 ENSG00000105497 Zinc finger protein 175 19 51571298-51592508 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002717 Uncertain Supported Nucleoplasm
Intermediate filaments
Cytosol Thyroid cancer:6.64e-4 (unfavourable) Mixed Mixed parathyroid gland: 19.7 Cell line enhanced HEL: 45.3 +PLA2G4C cPLA2-gamma ENSG00000105499 Phospholipase A2 group IVC 19 48047843-48110817 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA043083 Approved Approved Cytosol Mixed Mixed parathyroid gland: 29.7 Cell line enhanced HHSteC: 12.1;TIME: 17.1 +SIGLEC5 CD170, CD33L2, OB-BP2, SIGLEC-5 ENSG00000105501 Sialic acid binding Ig like lectin 5 19 51611927-51645545 CD markers, Predicted membrane proteins Evidence at protein level HPA009085, CAB024900 Supported Tissue enhanced Tissue enhanced appendix: 9.3;bone marrow: 9.7;spleen: 8.8 lymph node: 3.5 Group enriched 7 HMC-1: 52.0;U-937: 19.9 +CABP5 CABP3 ENSG00000105507 Calcium binding protein 5 19 48029953-48044053 Predicted intracellular proteins Evidence at protein level HPA043698 Supported Not detected Not detected bone marrow,epididymis,spleen: 0.1 Not detected +HAS1 HAS ENSG00000105509 Hyaluronan synthase 1 19 51713112-51723994 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA067602 Approved Supported Nucleoplasm
Plasma membrane Mixed Tissue enhanced adipose tissue: 27.0 appendix: 8.9 Group enriched 12 hTEC/SVTERT24-B: 27.0;U-87 MG: 110.6 +RAB3D D2-2, GOV, RAB16, RAD3D ENSG00000105514 RAB3D, member RAS oncogene family 19 11322046-11346270 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018067, HPA063283 Approved Approved Vesicles Glioma:3.30e-4 (unfavourable) Expressed in all Tissue enhanced skin: 62.5 esophagus: 28.1 Cell line enhanced SK-BR-3: 51.2 +DBP DABP ENSG00000105516 D-box binding PAR bZIP transcription factor 19 48630030-48637438 Predicted intracellular proteins, Transcription factors Evidence at protein level Lung cancer:1.16e-5 (favourable), Renal cancer:2.41e-5 (favourable), Head and neck cancer:5.49e-4 (favourable) Expressed in all Expressed in all thyroid gland: 41.4 Cell line enhanced NB-4: 148.5 +TMEM205 MBC3205, UNQ501 ENSG00000105518 Transmembrane protein 205 19 11342776-11346518 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA041504 Approved Approved Nucleoplasm
Nuclear membrane
Endoplasmic reticulum Expressed in all Expressed in all parathyroid gland: 258.0 Expressed in all +CAPS CAPS1, MGC126562 ENSG00000105519 Calcyphosine 19 5911707-5915877 Predicted intracellular proteins Evidence at protein level HPA043520 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Endometrial cancer:7.63e-5 (favourable), Head and neck cancer:8.60e-4 (favourable) Tissue enriched Tissue enriched 10 fallopian tube: 448.7 lung: 45.1 Cell line enhanced SK-BR-3: 46.0 +PLPPR2 LPPR2, PRG-4 ENSG00000105520 Phospholipid phosphatase related 2 19 11355386-11365698 Enzymes, Predicted membrane proteins Evidence at protein level HPA048973 Uncertain Approved Nucleoplasm Renal cancer:7.46e-11 (unfavourable), Colorectal cancer:6.45e-4 (unfavourable), Pancreatic cancer:6.82e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 77.2 Cell line enhanced U-2197: 88.4 +FAM83E FLJ20200 ENSG00000105523 Family with sequence similarity 83 member E 19 48600810-48614854 Predicted intracellular proteins Evidence at protein level HPA049305 Uncertain Mixed Tissue enhanced duodenum: 30.8;small intestine: 35.3;stomach: 40.7 colon: 22.5 Cell line enhanced CAPAN-2: 2.9 +RASIP1 FLJ20401, RAIN ENSG00000105538 Ras interacting protein 1 19 48720587-48740721 Predicted intracellular proteins Evidence at protein level HPA077251 Approved Head and neck cancer:7.17e-5 (favourable), Pancreatic cancer:9.46e-4 (favourable) Expressed in all Mixed spleen: 17.8 Cell line enhanced HEK 293: 12.7;HUVEC TERT2: 30.5;SiHa: 20.8;TIME: 40.9 +THEG CT56, THEG1 ENSG00000105549 Theg spermatid protein 19 361747-376670 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 9 testis: 33.5 skin: 3.9 Cell line enriched 5 HDLM-2: 79.5 +FGF21 ENSG00000105550 Fibroblast growth factor 21 19 48755559-48758330 Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA061286 Supported Tissue enriched Tissue enriched 38 liver: 6.6 thyroid gland: 0.1 Group enriched 8 HHSteC: 1.2;U-2 OS: 5.2 +BCAT2 BCAM, BCT2 ENSG00000105552 Branched chain amino acid transaminase 2 19 48795062-48811029 Enzymes, Predicted intracellular proteins Evidence at protein level HPA054091 Enhanced Renal cancer:3.68e-5 (favourable) Expressed in all Expressed in all adrenal gland: 54.1 Expressed in all +MIER2 KIAA1193 ENSG00000105556 MIER family member 2 19 301444-344815 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041439 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:7.22e-6 (unfavourable), Endometrial cancer:1.72e-5 (favourable), Colorectal cancer:2.89e-4 (unfavourable) Expressed in all Mixed testis: 12.8 Mixed +PLEKHA4 PEPP1 ENSG00000105559 Pleckstrin homology domain containing A4 19 48837097-48868632 Predicted intracellular proteins Evidence at protein level HPA042978, HPA048473 Uncertain Approved Plasma membrane
Cytokinetic bridge
Centrosome
Cytosol Breast cancer:1.97e-4 (favourable), Liver cancer:8.68e-4 (unfavourable) Expressed in all Mixed ovary: 22.3 Cell line enhanced AN3-CA: 58.6;BJ hTERT+ SV40 Large T+ RasG12V: 48.0;SK-MEL-30: 57.7 +PPP2R1A PP2A-Aalpha, PP2AA, PR65A ENSG00000105568 Protein phosphatase 2 scaffold subunit Aalpha 19 52190039-52229533 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018599 Approved Cytosol Renal cancer:1.20e-4 (favourable), Liver cancer:1.76e-4 (unfavourable), Lung cancer:2.50e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 207.6 Expressed in all +TNPO2 FLJ12155, IPO3, KPNB2B, TRN2 ENSG00000105576 Transportin 2 19 12699194-12724011 Predicted intracellular proteins, Transporters Evidence at protein level CAB046446, HPA071498 Approved Approved Nucleus
Nucleoli Endometrial cancer:7.16e-5 (unfavourable), Renal cancer:8.18e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 90.9 Expressed in all +WDR83OS C19orf56, PTD008 ENSG00000105583 WD repeat domain 83 opposite strand 19 12668071-12671356 Predicted membrane proteins Evidence at protein level HPA065685 Approved Approved Endoplasmic reticulum Lung cancer:2.09e-4 (favourable), Ovarian cancer:8.84e-4 (favourable) Expressed in all Expressed in all fallopian tube: 320.1 Expressed in all +CACNG7 ENSG00000105605 Calcium voltage-gated channel auxiliary subunit gamma 7 19 53909335-53943941 Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Tissue enriched 101 cerebral cortex: 63.7 adrenal gland: 0.6 Cell line enhanced AF22: 52.2;HMC-1: 36.0;NTERA-2: 14.0;SH-SY5Y: 34.2 +GCDH ACAD5 ENSG00000105607 Glutaryl-CoA dehydrogenase 19 12891026-12914207 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043252, HPA048492 Enhanced Supported Mitochondria Renal cancer:6.79e-8 (favourable), Liver cancer:7.28e-5 (favourable), Lung cancer:3.35e-4 (favourable) Expressed in all Expressed in all liver: 42.9 Expressed in all +LILRB5 CD85c, LIR-8, LIR8 ENSG00000105609 Leukocyte immunoglobulin like receptor B5 19 54249431-54257301 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA012069 Approved Mixed Tissue enhanced spleen: 26.1 adipose tissue: 11.4 Not detected +KLF1 EKLF ENSG00000105610 Kruppel like factor 1 19 12884423-12887181 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051850 Enhanced Supported Nucleoplasm Not detected Tissue enriched 24 bone marrow: 25.7 placenta: 1.0 Group enriched 33 HEL: 56.0;K-562: 136.3 +DNASE2 DNL, DNL2 ENSG00000105612 Deoxyribonuclease 2, lysosomal 19 12875211-12881468 Enzymes, Predicted secreted proteins Evidence at protein level HPA066185 Enhanced Expressed in all Expressed in all thyroid gland: 59.0 Expressed in all +MAST1 KIAA0973, SAST ENSG00000105613 Microtubule associated serine/threonine kinase 1 19 12833951-12874951 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028181, HPA073106 Enhanced Approved Vesicles Tissue enhanced Tissue enriched 12 cerebral cortex: 35.2 testis: 3.0 Cell line enhanced AN3-CA: 21.6;SCLC-21H: 47.7;SH-SY5Y: 21.4 +LENG1 ENSG00000105617 Leukocyte receptor cluster member 1 19 54155161-54159882 Predicted intracellular proteins Evidence at protein level HPA043541 Uncertain Approved Nucleus
Plasma membrane Renal cancer:3.72e-4 (favourable), Pancreatic cancer:8.12e-4 (favourable) Expressed in all Tissue enhanced spleen: 1.8 endometrium: 1.0 Cell line enhanced AF22: 3.2;HaCaT: 4.1;HDLM-2: 2.8;LHCN-M2: 2.3;U-87 MG: 3.1 +PRPF31 hPrp31, NY-BR-99, PRP31, RP11, SNRNP61 ENSG00000105618 Pre-mRNA processing factor 31 19 54115410-54131719 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041939, HPA061873 Supported Supported Nucleus Liver cancer:7.33e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 26.7 Expressed in all +TFPT amida, FB1, INO80F ENSG00000105619 TCF3 fusion partner 19 54107013-54115675 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034958, HPA058534 Approved Supported Nucleoplasm
Nuclear membrane Pancreatic cancer:3.13e-4 (favourable), Colorectal cancer:5.13e-4 (unfavourable), Liver cancer:5.25e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 10.6 Mixed +JAK3 JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK ENSG00000105639 Janus kinase 3 19 17824780-17848071 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA070314 Enhanced Renal cancer:2.89e-14 (unfavourable), Cervical cancer:6.42e-5 (favourable) Expressed in all Tissue enhanced appendix: 48.4;lymph node: 46.6 tonsil: 27.2 Cell line enhanced HDLM-2: 33.0;Karpas-707: 28.7;U-266/84: 17.1;U-937: 18.8 +RPL18A L18A ENSG00000105640 Ribosomal protein L18a 19 17859876-17864153 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055259 Approved Approved Nucleoli
Cytosol Renal cancer:1.48e-4 (unfavourable) Expressed in all Expressed in all ovary: 3084.5 Expressed in all +SLC5A5 NIS ENSG00000105641 Solute carrier family 5 member 5 19 17871973-17895174 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB022364, HPA049055 Enhanced Mixed Tissue enhanced salivary gland: 28.3;stomach: 56.1;thyroid gland: 20.7 cervix, uterine: 8.3 Cell line enriched 5 BEWO: 10.8 +KCNN1 hSK1, KCa2.1 ENSG00000105642 Potassium calcium-activated channel subfamily N member 1 19 17951293-18000080 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA065938 Approved Actin filaments
Cytosol Tissue enhanced Tissue enriched 10 cerebral cortex: 21.4 testis: 2.0 Cell line enriched 13 REH: 141.4 +ARRDC2 CLONE24945, PP2703 ENSG00000105643 Arrestin domain containing 2 19 18001132-18014102 Predicted intracellular proteins Evidence at protein level HPA053788 Uncertain Approved Nucleoplasm
Cytosol Urothelial cancer:2.92e-4 (favourable), Ovarian cancer:5.84e-4 (unfavourable), Cervical cancer:5.93e-4 (favourable), Thyroid cancer:6.91e-4 (favourable) Expressed in all Expressed in all bone marrow: 51.0 Mixed +PIK3R2 p85, P85B ENSG00000105647 Phosphoinositide-3-kinase regulatory subunit 2 19 18153118-18170540 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA069291 Approved Approved Golgi apparatus Mixed Expressed in all cerebral cortex: 47.3 Expressed in all +RAB3A ENSG00000105649 RAB3A, member RAS oncogene family 19 18196784-18204074 Predicted intracellular proteins Evidence at protein level HPA003160, CAB009949, CAB078998 Enhanced Supported Approved Nucleoplasm
Centrosome
Cytosol Renal cancer:6.14e-7 (favourable), Endometrial cancer:3.17e-4 (unfavourable) Expressed in all Tissue enriched 12 cerebral cortex: 250.5 adrenal gland: 20.6 Cell line enhanced SCLC-21H: 43.5;U-2197: 23.9 +PDE4C DPDE1 ENSG00000105650 Phosphodiesterase 4C 19 18207961-18255419 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA048975 Enhanced Mixed Mixed endometrium: 7.4 Cell line enhanced BEWO: 3.8;U-87 MG: 5.5 +ISYNA1 Ino1, INOS, IPS ENSG00000105655 Inositol-3-phosphate synthase 1 19 18434388-18438301 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007931, HPA008232, CAB020720 Enhanced Approved Nucleus
Cytosol Renal cancer:9.23e-4 (unfavourable) Expressed in all Tissue enhanced testis: 117.3 placenta: 63.8 Cell line enhanced BEWO: 475.1 +ELL C19orf17, ELL1, Men, PPP1R68 ENSG00000105656 Elongation factor for RNA polymerase II 19 18442663-18522127 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046076 Uncertain Expressed in all Expressed in all testis: 25.2 Expressed in all +CRTC1 FLJ14027, KIAA0616, MECT1, TORC1 ENSG00000105662 CREB regulated transcription coactivator 1 19 18683677-18782333 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA022035 Approved Supported Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Pancreatic cancer:1.80e-5 (favourable), Renal cancer:3.83e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 23.7 Expressed in all +COMP EDM1, EPD1, MED, PSACH, THBS5 ENSG00000105664 Cartilage oligomeric matrix protein 19 18782773-18791314 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA077555 Approved Golgi apparatus Renal cancer:1.52e-6 (unfavourable), Colorectal cancer:9.08e-5 (unfavourable), Endometrial cancer:2.04e-4 (unfavourable), Urothelial cancer:6.95e-4 (unfavourable) Mixed Tissue enhanced gallbladder: 24.5 smooth muscle: 18.2 Cell line enriched 5 fHDF/TERT166: 666.2 +UPK1A TSPAN21 ENSG00000105668 Uroplakin 1A 19 35666516-35678483 Predicted membrane proteins, Transporters Evidence at protein level HPA049879 Enhanced Tissue enriched Tissue enhanced esophagus: 26.9;urinary bladder: 108.7 skin: 15.6 Cell line enriched 9 RT4: 31.3 +COPE epsilon-COP ENSG00000105669 Coatomer protein complex subunit epsilon 19 18899514-18919397 Predicted intracellular proteins Evidence at protein level CAB034345, HPA041605, HPA043576 Supported Enhanced Golgi apparatus Cervical cancer:2.41e-4 (favourable) Expressed in all Expressed in all testis: 122.6 Expressed in all +DDX49 FLJ10432 ENSG00000105671 DEAD-box helicase 49 19 18919675-18928633 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041870, HPA048093 Enhanced Approved Nucleoli
Mitochondria Cervical cancer:2.01e-6 (favourable), Renal cancer:7.44e-5 (unfavourable), Liver cancer:7.05e-4 (unfavourable) Expressed in all Expressed in all testis: 24.3 Expressed in all +ETV2 ER71 ENSG00000105672 ETS variant 2 19 35641745-35644871 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Tissue enhanced testis: 8.7 duodenum: 2.1 Mixed +ATP4A ATP6A ENSG00000105675 ATPase H+/K+ transporting alpha subunit 19 35550043-35563658 Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039154 Enhanced Tissue enriched Tissue enriched 260 stomach: 557.9 pancreas: 2.1 Not detected +ARMC6 MGC19595 ENSG00000105676 Armadillo repeat containing 6 19 19033575-19060311 Predicted intracellular proteins Evidence at protein level HPA041420, HPA041681 Supported Enhanced Cytosol Expressed in all Expressed in all testis: 28.7 Expressed in all +TMEM147 MGC1936, NIFIE14 ENSG00000105677 Transmembrane protein 147 19 35545595-35547526 Predicted membrane proteins Evidence at protein level HPA067837 Uncertain Golgi apparatus
Actin filaments
Cytosol Liver cancer:4.98e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 120.6 Expressed in all +GAPDHS GAPD2, GAPDH-2, GAPDS ENSG00000105679 Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 19 35533412-35545316 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042666 Enhanced Approved Nucleoplasm
Centrosome Tissue enriched Tissue enriched 13 testis: 242.8 thyroid gland: 19.0 Mixed +MAG GMA, S-MAG, SIGLEC-4A, SIGLEC4A ENSG00000105695 Myelin associated glycoprotein 19 35292125-35313804 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009345, HPA012499 Enhanced Tissue enriched Tissue enriched 6 cerebral cortex: 163.6 ovary: 27.5 Cell line enriched 31 WM-115: 35.4 +TMEM59L BSMAP, C19orf4 ENSG00000105696 Transmembrane protein 59 like 19 18607430-18621039 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level HPA010661, HPA070701 Approved Approved Nucleoplasm
Actin filaments Endometrial cancer:1.62e-4 (unfavourable), Pancreatic cancer:8.80e-4 (favourable) Tissue enriched Tissue enriched 16 cerebral cortex: 366.3 adrenal gland: 22.2 Cell line enhanced AN3-CA: 33.4;ASC diff: 29.2;EFO-21: 24.0;Hep G2: 18.4;SH-SY5Y: 22.4 +HAMP HEPC, HFE2B, LEAP-1, LEAP1 ENSG00000105697 Hepcidin antimicrobial peptide 19 35280716-35285143 Disease related genes, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level Group enriched Tissue enriched 12 liver: 259.1 heart muscle: 21.9 Cell line enriched 127 Hep G2: 135.7 +USF2 bHLHb12, FIP ENSG00000105698 Upstream transcription factor 2, c-fos interacting 19 35268978-35279821 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029764, HPA046567 Supported Nucleoplasm
Vesicles Pancreatic cancer:5.12e-5 (favourable), Urothelial cancer:3.28e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 215.5 Expressed in all +LSR ILDR3, LISCH7 ENSG00000105699 Lipolysis stimulated lipoprotein receptor 19 35248330-35267964 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007270 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:8.09e-4 (favourable) Expressed in all Expressed in all stomach: 128.7 Cell line enhanced A-431: 435.7 +KXD1 BORCS4, C19orf50, FLJ25480, KXDL, MGC2749 ENSG00000105700 KxDL motif containing 1 19 18557762-18569387 Predicted intracellular proteins Evidence at protein level HPA041507, HPA041599 Approved Approved Nucleoli fibrillar center
Centrosome
Cytosol Renal cancer:7.71e-10 (unfavourable), Liver cancer:8.46e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 91.9 Expressed in all +FKBP8 FKBP38, FKBPr38 ENSG00000105701 FK506 binding protein 8 19 18531751-18544077 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025346, HPA045177 Supported Supported Endoplasmic reticulum
Mitochondria
Cytosol Colorectal cancer:1.24e-4 (unfavourable), Pancreatic cancer:7.76e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 354.7 Expressed in all +SUGP1 DKFZp434E2216, F23858, RBP, SF4 ENSG00000105705 SURP and G-patch domain containing 1 19 19276018-19320844 Predicted intracellular proteins Evidence at protein level HPA004890 Approved Enhanced Nucleoplasm Expressed in all Mixed testis: 17.0 Expressed in all +HPN TMPRSS1 ENSG00000105707 Hepsin 19 35040506-35066571 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006804 Approved Renal cancer:5.45e-5 (favourable) Tissue enhanced Tissue enhanced kidney: 99.7;liver: 155.4 prostate: 31.6 Group enriched 7 EFO-21: 29.1;Hep G2: 31.2;T-47d: 20.3 +ZNF14 GIOT-4, KOX6 ENSG00000105708 Zinc finger protein 14 19 19710471-19733097 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049863 Uncertain Approved Nucleus
Cytosol Renal cancer:8.09e-6 (favourable), Lung cancer:7.96e-4 (favourable) Expressed in all Mixed thyroid gland: 13.3 Mixed +SCN1B ENSG00000105711 Sodium voltage-gated channel beta subunit 1 19 35030466-35040449 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Pancreatic cancer:1.38e-4 (favourable) Expressed in all Tissue enhanced skeletal muscle: 145.1 cerebral cortex: 52.4 Cell line enhanced A549: 15.7;TIME: 21.3 +PBX4 ENSG00000105717 PBX homeobox 4 19 19561707-19618916 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049859, HPA056469 Enhanced Enhanced Vesicles Urothelial cancer:5.94e-7 (favourable), Cervical cancer:8.69e-6 (favourable) Mixed Tissue enhanced testis: 2.6;thyroid gland: 2.2 lymph node: 0.8 Cell line enhanced PC-3: 1.5;RT4: 1.6 +ERF PE-2, PE2 ENSG00000105722 ETS2 repressor factor 19 42247572-42255157 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058532, HPA067952 Approved Enhanced Nucleoplasm Breast cancer:8.07e-4 (favourable) Expressed in all Expressed in all gallbladder: 78.9 Expressed in all +GSK3A ENSG00000105723 Glycogen synthase kinase 3 alpha 19 42230186-42242625 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB004422, HPA028423 Approved Approved Cytosol Liver cancer:1.13e-4 (unfavourable), Endometrial cancer:4.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 74.5 Expressed in all +ATP13A1 ATP13A, CGI-152, FLJ31858, KIAA1825 ENSG00000105726 ATPase 13A1 19 19645198-19663693 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA031798, HPA049717 Approved Approved Vesicles Renal cancer:6.51e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 52.5 Expressed in all +ZNF574 FLJ22059 ENSG00000105732 Zinc finger protein 574 19 42068477-42081549 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023196, HPA057274 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 36.5 Expressed in all +GRIK5 GluK5, GRIK2, KA2 ENSG00000105737 Glutamate ionotropic receptor kainate type subunit 5 19 41998321-42069498 Predicted membrane proteins Evidence at protein level HPA074001 Supported Nucleus
Plasma membrane Pancreatic cancer:7.23e-4 (favourable), Renal cancer:9.32e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 30.8;parathyroid gland: 22.1 testis: 18.8 Cell line enhanced HEL: 12.3;NTERA-2: 13.1;REH: 34.1;SCLC-21H: 12.1;SH-SY5Y: 24.1 +SIPA1L3 KIAA0545 ENSG00000105738 Signal induced proliferation associated 1 like 3 19 37907228-38208372 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042072, HPA045480 Uncertain Approved Nuclear membrane
Nuclear speckles Expressed in all Mixed small intestine: 19.8 Expressed in all +ZNF85 HPF4, HTF1 ENSG00000105750 Zinc finger protein 85 19 20923222-20950697 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044760 Uncertain Supported Nucleus Ovarian cancer:6.45e-6 (favourable), Endometrial cancer:5.20e-5 (unfavourable) Mixed Tissue enhanced testis: 28.0 thyroid gland: 12.0 Mixed +ETHE1 HSCO, YF13H12 ENSG00000105755 ETHE1, persulfide dioxygenase 19 43506719-43527244 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028360, HPA029028, HPA029029 Enhanced Enhanced Mitochondria Lung cancer:9.58e-4 (unfavourable) Expressed in all Expressed in all colon: 240.2 Mixed +CADM4 IGSF4C, Necl-4, SynCAM4, TSLL2 ENSG00000105767 Cell adhesion molecule 4 19 43622368-43639839 Predicted membrane proteins Evidence at protein level HPA012612 Enhanced Approved Nucleus
Nuclear membrane Renal cancer:2.28e-6 (favourable) Expressed in all Tissue enhanced cerebral cortex: 163.6 parathyroid gland: 59.1 Cell line enriched 5 WM-115: 552.4 +SMG9 C19orf61, FLJ12886 ENSG00000105771 SMG9, nonsense mediated mRNA decay factor 19 43727992-43754990 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041763, HPA042096 Uncertain Approved Mitochondria
Cytosol Liver cancer:2.15e-5 (unfavourable), Renal cancer:1.71e-4 (unfavourable), Urothelial cancer:8.09e-4 (favourable) Expressed in all Tissue enhanced testis: 48.9 lymph node: 14.8 Expressed in all +AVL9 KIAA0241 ENSG00000105778 AVL9 cell migration associated 7 32495426-32588721 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050957 Approved Approved Endoplasmic reticulum Expressed in all Expressed in all cerebral cortex: 25.5 Mixed +RUNDC3B RPIB9, RPIP9 ENSG00000105784 RUN domain containing 3B 7 87627548-87832296 Predicted intracellular proteins Evidence at protein level HPA056968, HPA057155 Uncertain Renal cancer:2.62e-6 (favourable) Mixed Tissue enhanced adrenal gland: 9.7 cerebral cortex: 7.2 Cell line enhanced SCLC-21H: 3.1;SH-SY5Y: 1.3 +CFAP69 C7orf63, FAP69, FLJ21062 ENSG00000105792 Cilia and flagella associated protein 69 7 90245174-90311063 Predicted intracellular proteins Evidence at protein level HPA062883 Uncertain Tissue enhanced Tissue enhanced prostate: 25.2 fallopian tube: 17.9 Mixed +GTPBP10 DKFZP686A10121, FLJ38242, OBGH2 ENSG00000105793 GTP binding protein 10 7 90335223-90391455 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021076 Approved Renal cancer:6.76e-5 (favourable) Expressed in all Expressed in all testis: 20.3 Expressed in all +RASA4 CAPRI, GAPL, KIAA0538 ENSG00000105808 RAS p21 protein activator 4 7 102573807-102616757 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level HPA043010 Uncertain Uncertain Vesicles Not detected Expressed in all skeletal muscle: 85.0 Cell line enhanced SH-SY5Y: 34.2;U-138 MG: 44.7 +CDK6 PLSTIRE ENSG00000105810 Cyclin dependent kinase 6 7 92604921-92836594 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002637, CAB004363 Enhanced Supported Nucleoplasm
Cytosol Pancreatic cancer:3.86e-6 (unfavourable), Urothelial cancer:2.33e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 34.2 Cell line enhanced MOLT-4: 366.7;REH: 201.1 +PMPCB MPPB, MPPP52 ENSG00000105819 Peptidase, mitochondrial processing beta subunit 7 103297422-103329511 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040674, HPA074168 Approved Supported Mitochondria Renal cancer:2.95e-8 (favourable), Breast cancer:2.79e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 70.0 Expressed in all +DNAJC2 MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin ENSG00000105821 DnaJ heat shock protein family (Hsp40) member C2 7 103312474-103344873 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020454 Approved Supported Cytosol Renal cancer:1.12e-5 (unfavourable) Expressed in all Expressed in all testis: 61.7 Expressed in all +TFPI2 PP5, REF1, TFPI-2 ENSG00000105825 Tissue factor pathway inhibitor 2 7 93885397-93890991 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010142, HPA049158 Enhanced Breast cancer:8.33e-7 (favourable), Endometrial cancer:5.42e-4 (favourable), Renal cancer:8.53e-4 (unfavourable) Expressed in all Tissue enriched 23 placenta: 1208.2 ovary: 52.0 Cell line enhanced EFO-21: 1987.5;hTEC/SVTERT24-B: 1055.6;U-138 MG: 999.0;U-2197: 850.7;U-87 MG: 1680.0 +BET1 hbet1 ENSG00000105829 Bet1 golgi vesicular membrane trafficking protein 7 93962762-94004382 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Glioma:9.38e-5 (unfavourable), Renal cancer:1.32e-4 (unfavourable) Expressed in all Expressed in all placenta: 51.4 Expressed in all +NAMPT PBEF, PBEF1 ENSG00000105835 Nicotinamide phosphoribosyltransferase 7 106248285-106286326 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034349, HPA047776, HPA057722 Approved Approved Nuclear speckles
Cell Junctions Renal cancer:2.49e-6 (unfavourable), Pancreatic cancer:1.51e-4 (unfavourable), Cervical cancer:4.78e-4 (unfavourable), Head and neck cancer:8.81e-4 (unfavourable) Expressed in all Expressed in all appendix: 778.1 Expressed in all +TWISTNB ENSG00000105849 TWIST neighbor 7 19695462-19709087 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA019071, HPA022416 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:1.85e-4 (unfavourable) Expressed in all Expressed in all endometrium: 19.7 Expressed in all +PIK3CG ENSG00000105851 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 7 106865278-106907145 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA069976 Supported Plasma membrane Mixed Tissue enhanced bone marrow: 28.1 lymph node: 22.0 Cell line enhanced HMC-1: 30.6;MOLT-4: 44.8;U-266/70: 53.9;U-937: 40.5 +PON3 ENSG00000105852 Paraoxonase 3 7 95359944-95396368 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA014848, CAB025250 Enhanced Group enriched Tissue enriched 8 liver: 328.5 breast: 43.4 Cell line enhanced A549: 26.6;CACO-2: 7.9;Hep G2: 22.5;T-47d: 17.0 +PON2 ENSG00000105854 Paraoxonase 2 7 95404863-95435329 Candidate cardiovascular disease genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025430, HPA029193 Enhanced Renal cancer:4.30e-8 (unfavourable), Cervical cancer:1.43e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 226.2 Mixed +ITGB8 ENSG00000105855 Integrin subunit beta 8 7 20330702-20415754 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA027796, HPA027797 Supported Approved Plasma membrane
Cytosol Renal cancer:1.77e-4 (favourable) Mixed Mixed cerebral cortex: 30.8 Cell line enhanced AF22: 45.0;EFO-21: 54.7;RPTEC TERT1: 68.8;WM-115: 130.0 +HBP1 ENSG00000105856 HMG-box transcription factor 1 7 107168961-107202529 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020225, CAB032824 Approved Enhanced Nuclear speckles Renal cancer:7.70e-5 (favourable) Expressed in all Expressed in all thyroid gland: 54.2 Expressed in all +DUS4L DUS4, PP35 ENSG00000105865 Dihydrouridine synthase 4 like 7 107563484-107578464 Predicted intracellular proteins Evidence at protein level HPA044301 Approved Approved Cytosol Expressed in all Mixed thyroid gland: 2.4 Mixed +SP4 HF1B, MGC130008, MGC130009, SPR-1 ENSG00000105866 Sp4 transcription factor 7 21428034-21514822 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB010246, HPA040395 Uncertain Enhanced Nucleoplasm
Cytosol Expressed in all Mixed parathyroid gland: 14.9 Cell line enhanced REH: 24.6 +WDR91 HSPC049, SORF-1 ENSG00000105875 WD repeat domain 91 7 135183839-135211534 Predicted intracellular proteins Evidence at protein level HPA024260 Uncertain Liver cancer:1.53e-4 (unfavourable) Expressed in all Mixed fallopian tube: 14.7 Expressed in all +DNAH11 CILD7, DNAHBL, Dnahc11, DNHBL, DPL11 ENSG00000105877 Dynein axonemal heavy chain 11 7 21543215-21901839 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045880, HPA056474 Approved Renal cancer:1.49e-7 (unfavourable) Mixed Tissue enriched 17 parathyroid gland: 145.0 fallopian tube: 8.5 Cell line enhanced U-2 OS: 1.1;U-2197: 1.2 +CBLL1 FLJ23109, HAKAI, RNF188 ENSG00000105879 Cbl proto-oncogene like 1 7 107743697-107761667 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021773, HPA026699 Enhanced Supported Nuclear speckles Expressed in all Expressed in all testis: 36.2 Expressed in all +DLX5 ENSG00000105880 Distal-less homeobox 5 7 97020392-97025097 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005670 Approved Approved Nucleus Tissue enriched Tissue enhanced endometrium: 20.2;placenta: 13.5;skin: 17.1 cervix, uterine: 9.6 Group enriched 5 BEWO: 41.0;HAP1: 24.0 +MTPN GCDP, MYOTROPHIN, V-1 ENSG00000105887 Myotrophin 7 135926761-135977353 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019735 Approved Approved Plasma membrane
Cytosol Liver cancer:1.19e-4 (unfavourable), Pancreatic cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 193.6 Expressed in all +STEAP1B ENSG00000105889 STEAP family member 1B 7 22419444-22632925 Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced testis: 5.3 spleen: 3.4 Cell line enhanced hTEC/SVTERT24-B: 75.9;HUVEC TERT2: 72.0;K-562: 46.3;WM-115: 93.7 +PTN HBGF8, HBNF, NEGF1 ENSG00000105894 Pleiotrophin 7 137227341-137343865 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB017685 Enhanced Renal cancer:1.35e-4 (favourable) Tissue enriched Tissue enhanced parathyroid gland: 725.3 cerebral cortex: 269.6 Cell line enriched 12 AF22: 1551.5 +MPP6 p55T, PALS2, VAM-1 ENSG00000105926 Membrane palmitoylated protein 6 7 24573268-24694193 Predicted intracellular proteins Evidence at protein level HPA019085, HPA020456 Enhanced Renal cancer:3.05e-5 (favourable), Head and neck cancer:8.85e-5 (unfavourable), Endometrial cancer:1.46e-4 (unfavourable), Thyroid cancer:5.28e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 29.9;testis: 45.3 cerebral cortex: 14.9 Expressed in all +DFNA5 ICERE-1 ENSG00000105928 DFNA5, deafness associated tumor suppressor 7 24698353-24758113 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA011326, CAB019306 Approved Enhanced Cytosol Liver cancer:2.49e-5 (unfavourable) Mixed Mixed placenta: 58.7 Mixed +ATP6V0A4 a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2 ENSG00000105929 ATPase H+ transporting V0 subunit a4 7 138706295-138799560 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA018029, HPA064555 Enhanced Approved Cytosol Renal cancer:1.32e-6 (favourable) Tissue enriched Group enriched 9 kidney: 69.6;salivary gland: 31.6 breast: 5.5 Cell line enriched 12 SK-BR-3: 42.2 +ZC3HAV1 FLB6421, FLJ13288, MGC48898, PARP13, ZAP, ZC3H2, ZC3HDC2 ENSG00000105939 Zinc finger CCCH-type containing, antiviral 1 7 139043520-139109719 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047818, HPA059096 Approved Enhanced Golgi apparatus
Cytosol Liver cancer:8.77e-7 (unfavourable), Stomach cancer:6.86e-4 (favourable) Expressed in all Expressed in all bone marrow: 54.6 Expressed in all +TTC26 dyf-13, DYF13, FLJ12571, IFT56 ENSG00000105948 Tetratricopeptide repeat domain 26 7 139133744-139191986 Predicted intracellular proteins Evidence at protein level HPA036338, HPA036339 Enhanced Approved Nuclear speckles
Intermediate filaments
Cytosol Expressed in all Tissue enhanced fallopian tube: 22.6;testis: 22.1 parathyroid gland: 13.6 Expressed in all +OGDH E1k ENSG00000105953 Oxoglutarate dehydrogenase 7 44606572-44709066 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019514, HPA020347 Supported Enhanced Mitochondria Renal cancer:2.22e-14 (favourable) Expressed in all Expressed in all heart muscle: 147.8 Expressed in all +NPVF C7orf9, RFRP ENSG00000105954 Neuropeptide VF precursor 7 25224570-25228486 Predicted secreted proteins Evidence at protein level HPA041733 Approved Not detected Not detected tonsil: 0.3 Not detected +ADAP1 CENTA1, GCS1L ENSG00000105963 ArfGAP with dual PH domains 1 7 897901-955407 Predicted intracellular proteins Evidence at protein level HPA007033, HPA012049 Enhanced Supported Plasma membrane
Cytosol Renal cancer:4.13e-5 (favourable), Colorectal cancer:5.25e-4 (unfavourable), Head and neck cancer:9.13e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 80.4 colon: 37.9 Cell line enhanced A-431: 97.9;CAPAN-2: 69.1;HMC-1: 64.7;THP-1: 87.7 +TFEC bHLHe34, TCFEC, TFECL ENSG00000105967 Transcription factor EC 7 115935148-116159896 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB032260, HPA063577 Approved Supported Nucleoplasm Tissue enhanced Mixed appendix: 26.3 Cell line enhanced HEL: 14.6;HUVEC TERT2: 9.2;THP-1: 14.4;TIME: 10.2;U-937: 19.1 +H2AFV H2AV, MGC10170, MGC10831, MGC1947 ENSG00000105968 H2A histone family member V 7 44826791-44848083 Predicted intracellular proteins Evidence at protein level HPA057236 Supported Cervical cancer:4.66e-4 (favourable), Renal cancer:8.04e-4 (favourable) Expressed in all Expressed in all bone marrow: 218.5 Expressed in all +CAV2 CAV ENSG00000105971 Caveolin 2 7 116287380-116508541 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013488, HPA044810 Enhanced Approved Vesicles Head and neck cancer:5.80e-5 (unfavourable), Pancreatic cancer:1.21e-4 (unfavourable) Expressed in all Mixed adipose tissue: 233.6 Mixed +CAV1 CAV ENSG00000105974 Caveolin 1 7 116524785-116561184 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB003791, HPA049326 Enhanced Supported Golgi apparatus Lung cancer:7.17e-5 (unfavourable), Renal cancer:1.29e-4 (unfavourable) Expressed in all Tissue enhanced lung: 859.9 adipose tissue: 640.4 Cell line enhanced LHCN-M2: 1943.1 +MET DFNB97, HGFR, RCCP2 ENSG00000105976 MET proto-oncogene, receptor tyrosine kinase 7 116672390-116798386 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB005282, CAB018577, HPA055607 Uncertain Supported Plasma membrane
Cytosol Pancreatic cancer:1.21e-7 (unfavourable), Head and neck cancer:6.75e-4 (unfavourable) Expressed in all Expressed in all placenta: 39.0 Mixed +RNF32 FKSG33, HSD15, LMBR2 ENSG00000105982 Ring finger protein 32 7 156640281-156677130 Predicted intracellular proteins Evidence at protein level HPA073560 Enhanced Colorectal cancer:2.21e-4 (unfavourable) Mixed Tissue enriched 8 testis: 110.5 epididymis: 13.4 Cell line enhanced HDLM-2: 12.4 +LMBR1 ACHP, C7orf2, FLJ11665, ZRS ENSG00000105983 Limb development membrane protein 1 7 156668946-156893230 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016592 Approved Approved Cytosol Renal cancer:1.44e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 46.3 Expressed in all +WNT2 INT1L1, IRP ENSG00000105989 Wnt family member 2 7 117276631-117323289 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA020920 Approved Vesicles Mixed Group enriched 6 endometrium: 23.8;placenta: 93.2 lung: 9.2 Cell line enriched 6 U-2197: 19.1 +HOXA1 HOX1, HOX1F ENSG00000105991 Homeobox A1 7 27092993-27095996 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Head and neck cancer:6.73e-5 (unfavourable) Mixed Tissue enhanced urinary bladder: 8.4 parathyroid gland,skin: 2.7 Mixed +DNAJB6 LGMD1D, MRJ ENSG00000105993 DnaJ heat shock protein family (Hsp40) member B6 7 157335381-157417439 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004670, HPA024258, HPA058593 Enhanced Supported Nucleoplasm Liver cancer:1.12e-5 (unfavourable) Expressed in all Expressed in all testis: 220.1 Expressed in all +HOXA2 HOX1K ENSG00000105996 Homeobox A2 7 27100354-27102811 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA078220 Approved Nucleus
Vesicles Mixed Tissue enhanced parathyroid gland: 8.1 epididymis: 6.2 Cell line enhanced AN3-CA: 13.4;HaCaT: 5.3 +HOXA3 HOX1, HOX1E ENSG00000105997 Homeobox A3 7 27106184-27152581 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029157 Uncertain Supported Nucleoplasm Renal cancer:2.52e-6 (unfavourable) Mixed Mixed fallopian tube: 16.2 Cell line enhanced AN3-CA: 35.4;CAPAN-2: 58.4;HEK 293: 27.2;WM-115: 35.0 +LFNG SCDO3 ENSG00000106003 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 7 2512529-2529177 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA069130 Approved Endometrial cancer:6.36e-4 (favourable) Expressed in all Expressed in all skin: 68.5 Cell line enhanced RH-30: 44.5;U-2 OS: 52.5 +HOXA5 HOX1, HOX1C ENSG00000106004 Homeobox A5 7 27141052-27143668 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Endometrial cancer:2.28e-4 (unfavourable) Mixed Tissue enhanced adrenal gland: 109.7;epididymis: 60.1 fallopian tube: 44.1 Cell line enhanced AN3-CA: 86.9;HEK 293: 146.8 +HOXA6 HOX1, HOX1B ENSG00000106006 Homeobox A6 7 27145396-27150603 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA004203 Approved Endometrial cancer:1.40e-4 (unfavourable), Renal cancer:2.03e-4 (favourable) Mixed Tissue enhanced fallopian tube: 9.9 endometrium: 9.0 Group enriched 9 AN3-CA: 57.3;HEK 293: 77.5 +BRAT1 BAAT1, C7orf27, MGC22916 ENSG00000106009 BRCA1 associated ATM activator 1 7 2537877-2555727 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029455, HPA076508 Approved Supported Nucleoplasm Renal cancer:3.90e-4 (unfavourable), Liver cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all testis: 14.9 Expressed in all +IQCE KIAA1023 ENSG00000106012 IQ motif containing E 7 2558972-2614734 Predicted intracellular proteins Evidence at protein level HPA019515 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:5.91e-4 (favourable) Expressed in all Expressed in all testis: 51.5 Mixed +ANKRD7 TSA806 ENSG00000106013 Ankyrin repeat domain 7 7 118214669-118496171 Predicted intracellular proteins Evidence at protein level HPA043489 Approved Nucleus Tissue enhanced Tissue enriched 643 testis: 1542.7 epididymis: 2.3 Cell line enhanced SCLC-21H: 9.0;U-266/70: 7.5 +VIPR2 VPAC2, VPAC2R ENSG00000106018 Vasoactive intestinal peptide receptor 2 7 159028175-159144957 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA062707 Approved Tissue enhanced Tissue enhanced seminal vesicle: 28.3 epididymis: 14.9 Cell line enhanced HMC-1: 7.8;MOLT-4: 10.2;U-266/70: 30.8 +TSPAN12 NET-2, TM4SF12 ENSG00000106025 Tetraspanin 12 7 120787320-120858402 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA051570, HPA058244 Uncertain Approved Vesicles
Microtubules Expressed in all Mixed kidney: 91.5 Cell line enhanced HEK 293: 47.4;HUVEC TERT2: 48.1;RH-30: 50.5;RPTEC TERT1: 63.2;RT4: 52.1 +SSBP1 mtSSB, SSBP ENSG00000106028 Single stranded DNA binding protein 1 7 141738321-141787922 Predicted intracellular proteins Evidence at protein level HPA002866 Enhanced Supported Mitochondria Ovarian cancer:3.40e-4 (favourable), Liver cancer:4.42e-4 (unfavourable) Expressed in all Expressed in all testis: 147.7 Expressed in all +HOXA13 HOX1, HOX1J ENSG00000106031 Homeobox A13 7 27193503-27200106 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enhanced Tissue enhanced cervix, uterine: 34.0;placenta: 24.5;prostate: 36.2;seminal vesicle: 32.5 rectum: 13.0 Cell line enhanced HAP1: 27.6;HEK 293: 34.0;RT4: 33.4 +CPED1 C7orf58, FLJ21986 ENSG00000106034 Cadherin like and PC-esterase domain containing 1 7 120988677-121297444 Predicted intracellular proteins Evidence at transcript level HPA012058 Uncertain Approved Nucleus Lung cancer:3.00e-4 (favourable), Renal cancer:4.87e-4 (unfavourable) Mixed Mixed ovary: 96.6 Cell line enhanced BJ hTERT+: 70.8;K-562: 158.4 +EVX1 ENSG00000106038 Even-skipped homeobox 1 7 27242700-27250493 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055132 Approved Nucleoplasm Mixed Tissue enhanced adrenal gland: 3.7;prostate: 4.5;seminal vesicle: 4.0 testis: 1.3 Cell line enriched 10 RT4: 11.7 +HIBADH NS5ATP1 ENSG00000106049 3-hydroxyisobutyrate dehydrogenase 7 27525442-27662995 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA019522, HPA021002 Enhanced Renal cancer:5.56e-11 (favourable) Expressed in all Expressed in all kidney: 113.0 Expressed in all +TAX1BP1 CALCOCO3, TXBP151 ENSG00000106052 Tax1 binding protein 1 7 27739331-27844564 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024432 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:2.80e-6 (favourable), Pancreatic cancer:1.06e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 184.5 Expressed in all +CPVL ENSG00000106066 Carboxypeptidase, vitellogenic like 7 28995231-29195451 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB003697, HPA045715, HPA056466 Enhanced Supported Endoplasmic reticulum Endometrial cancer:8.56e-6 (unfavourable), Urothelial cancer:4.99e-4 (unfavourable) Expressed in all Expressed in all spleen: 301.8 Cell line enhanced BEWO: 183.9;RPTEC TERT1: 604.1 +CHN2 ARHGAP3, RhoGAP3 ENSG00000106069 Chimerin 2 7 29122274-29514328 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018989 Approved Approved Nucleus Mixed Tissue enhanced duodenum: 74.8;small intestine: 68.4 cerebral cortex: 31.7 Cell line enhanced HEL: 34.5;HMC-1: 60.7 +GRB10 ENSG00000106070 Growth factor receptor bound protein 10 7 50590063-50793462 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB019423, HPA027502, HPA031818 Approved Supported Vesicles Expressed in all Expressed in all thyroid gland: 44.9 Mixed +ABHD11 PP1226, WBSCR21 ENSG00000106077 Abhydrolase domain containing 11 7 73736094-73738867 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024042, HPA049641 Approved Supported Mitochondria Renal cancer:3.66e-7 (favourable) Expressed in all Expressed in all thyroid gland: 28.6 Expressed in all +COBL KIAA0633 ENSG00000106078 Cordon-bleu WH2 repeat protein 7 51016212-51316818 Predicted intracellular proteins Evidence at protein level HPA019033, HPA019167 Enhanced Approved Plasma membrane
Cell Junctions Renal cancer:5.21e-12 (favourable) Mixed Mixed parathyroid gland: 61.9 Cell line enhanced BEWO: 31.3;HeLa: 39.5;RPMI-8226: 32.2 +FKBP14 FKBP22, FLJ20731 ENSG00000106080 FK506 binding protein 14 7 30010587-30026684 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA013329, HPA026829 Uncertain Approved Nucleus
Golgi apparatus
Cytosol Breast cancer:1.60e-4 (unfavourable), Urothelial cancer:4.25e-4 (unfavourable), Stomach cancer:4.57e-4 (unfavourable), Liver cancer:6.87e-4 (unfavourable) Expressed in all Mixed smooth muscle: 20.3 Mixed +PLEKHA8 FAPP2, MGC3358 ENSG00000106086 Pleckstrin homology domain containing A8 7 30027404-30130483 Predicted intracellular proteins Evidence at protein level HPA072314 Supported Nucleoplasm
Golgi apparatus Expressed in all Mixed placenta: 11.6 Mixed +STX1A HPC-1, p35-1, STX1 ENSG00000106089 Syntaxin 1A 7 73699206-73719672 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB008372, HPA069176 Enhanced Endometrial cancer:1.94e-5 (unfavourable), Cervical cancer:3.63e-4 (unfavourable) Expressed in all Tissue enriched 15 cerebral cortex: 166.6 gallbladder: 10.8 Cell line enhanced SCLC-21H: 164.0;U-87 MG: 90.3 +NOD1 CARD4, CLR7.1, NLRC1 ENSG00000106100 Nucleotide binding oligomerization domain containing 1 7 30424527-30478784 Predicted intracellular proteins Evidence at protein level HPA074367 Approved Mitochondria Thyroid cancer:1.95e-4 (favourable), Renal cancer:6.68e-4 (unfavourable) Expressed in all Mixed lung: 17.9 Mixed +GARS CMT2D, DSMAV, GlyRS, SMAD1 ENSG00000106105 Glycyl-tRNA synthetase 7 30594681-30634033 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA017896, HPA019097 Enhanced Supported Cytosol Renal cancer:1.70e-5 (unfavourable), Urothelial cancer:3.04e-5 (unfavourable), Liver cancer:8.95e-5 (unfavourable), Breast cancer:1.02e-4 (unfavourable), Endometrial cancer:8.48e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 96.0 Expressed in all +CRHR2 CRF-RB, CRF2, HM-CRF ENSG00000106113 Corticotropin releasing hormone receptor 2 7 30651943-30700129 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA046683 Uncertain Not detected Tissue enhanced seminal vesicle: 1.7 cerebral cortex: 1.2 Not detected +EPHB6 HEP ENSG00000106123 EPH receptor B6 7 142855061-142871094 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035784 Approved Nuclear speckles Urothelial cancer:4.68e-5 (favourable), Cervical cancer:1.80e-4 (favourable), Glioma:6.96e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 22.5;skin: 25.0 cervix, uterine: 7.6 Group enriched 5 MOLT-4: 25.8;RT4: 47.4 +MINDY4 C7orf67, FAM188B, FLJ22374 ENSG00000106125 MINDY lysine 48 deubiquitinase 4 7 30771417-30892387 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019475, HPA030129, HPA030130 Approved Supported Vesicles
Cytosol Mixed Mixed fallopian tube: 18.6 Cell line enhanced K-562: 17.1 +GHRHR ENSG00000106128 Growth hormone releasing hormone receptor 7 30938669-30993254 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Tissue enhanced Not detected adrenal gland: 0.5 Not detected +CASP2 ICH1, MGC2181, NEDD2, PPP1R57 ENSG00000106144 Caspase 2 7 143288215-143307696 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012175, HPA050678 Approved Approved Nucleoplasm Renal cancer:5.01e-6 (unfavourable), Liver cancer:2.34e-4 (unfavourable), Ovarian cancer:2.89e-4 (favourable), Cervical cancer:7.38e-4 (favourable) Expressed in all Expressed in all lymph node: 24.9 Expressed in all +CHCHD2 C7orf17 ENSG00000106153 Coiled-coil-helix-coiled-coil-helix domain containing 2 7 56101569-56106576 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027407, HPA052510 Uncertain Enhanced Mitochondria Head and neck cancer:1.90e-5 (unfavourable), Liver cancer:9.41e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 585.7 Expressed in all +CCL24 Ckb-6, eotaxin-2, MPIF-2, MPIF2, SCYA24 ENSG00000106178 C-C motif chemokine ligand 24 7 75811665-75823356 Predicted secreted proteins Evidence at protein level Colorectal cancer:5.41e-4 (favourable) Tissue enhanced Tissue enhanced rectum: 111.7;small intestine: 96.2 urinary bladder: 51.4 Cell line enhanced CAPAN-2: 4.8;RH-30: 2.0;U-2 OS: 5.9 +HSPB1 CMT2F, Hs.76067, Hsp25, HSP27, HSP28 ENSG00000106211 Heat shock protein family B (small) member 1 7 76302544-76304295 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000497, CAB004439, CAB047330, CAB047331, CAB047332 Enhanced Enhanced Plasma membrane
Cytosol Colorectal cancer:9.94e-5 (unfavourable) Expressed in all Expressed in all esophagus: 1615.3 Expressed in all +NPTX2 ENSG00000106236 Neuronal pentraxin 2 7 98617297-98629868 Predicted secreted proteins Evidence at protein level CAB020801, HPA049799, HPA058320 Supported Approved Golgi apparatus
Actin filaments
Centrosome Renal cancer:5.46e-9 (unfavourable), Endometrial cancer:5.46e-5 (unfavourable) Expressed in all Tissue enhanced adrenal gland: 33.5;cerebral cortex: 80.3;testis: 44.3 cervix, uterine: 12.1 Cell line enriched 8 LHCN-M2: 600.5 +PDAP1 HASPP28, PAP, PAP1 ENSG00000106244 PDGFA associated protein 1 7 99392048-99408829 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB021103, HPA050294, HPA060836 Approved Enhanced Plasma membrane
Cytosol Liver cancer:6.67e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 37.3 Expressed in all +BUD31 Cwc14, EDG-2, EDG2, fSAP17, G10, YCR063W ENSG00000106245 BUD31 homolog 7 99408641-99419616 Predicted intracellular proteins Evidence at protein level HPA028943 Approved Approved Nucleus
Microtubules
Centrosome Renal cancer:9.66e-4 (unfavourable) Expressed in all Expressed in all testis: 97.5 Expressed in all +PTCD1 KIAA0632 ENSG00000106246 Pentatricopeptide repeat domain 1 7 99416739-99466163 Predicted intracellular proteins Evidence at protein level HPA020106, HPA047679 Uncertain Approved Mitochondria Renal cancer:1.13e-4 (unfavourable), Liver cancer:2.34e-4 (unfavourable) Expressed in all Mixed skin: 5.0 Expressed in all +CYP3A5 CP35, P450PCN3, PCN3 ENSG00000106258 Cytochrome P450 family 3 subfamily A member 5 7 99648194-99679998 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA072245 Uncertain Cytosol Liver cancer:3.72e-5 (favourable) Tissue enhanced Tissue enhanced duodenum: 114.8;liver: 93.2;small intestine: 187.6 stomach: 77.7 Cell line enhanced A549: 2.5;CACO-2: 7.9;CAPAN-2: 5.7;Hep G2: 5.0 +ZKSCAN1 KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33 ENSG00000106261 Zinc finger with KRAB and SCAN domains 1 7 100015572-100041689 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006672 Uncertain Approved Nucleus
Nuclear bodies
Mitochondria Expressed in all Expressed in all skin: 38.9 Expressed in all +EIF3B eIF3b, EIF3S9, PRT1 ENSG00000106263 Eukaryotic translation initiation factor 3 subunit B 7 2354086-2380745 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017562, HPA048983 Approved Approved Nucleoplasm
Cytosol Liver cancer:4.41e-9 (unfavourable), Renal cancer:9.66e-6 (unfavourable), Head and neck cancer:2.20e-4 (unfavourable) Expressed in all Expressed in all testis: 103.1 Expressed in all +SNX8 Mvp1 ENSG00000106266 Sorting nexin 8 7 2251770-2354318 Predicted intracellular proteins Evidence at protein level HPA057296, HPA060194 Approved Supported Vesicles Liver cancer:8.47e-6 (unfavourable) Expressed in all Expressed in all spleen: 38.0 Expressed in all +NUDT1 MTH1 ENSG00000106268 Nudix hydrolase 1 7 2242222-2251146 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA012636 Approved Approved Cytosol Renal cancer:1.30e-7 (unfavourable), Liver cancer:4.44e-4 (unfavourable) Expressed in all Expressed in all testis: 50.4 Expressed in all +PTPRZ1 phosphacan, PTP18, PTPRZ, PTPZ, RPTPB ENSG00000106278 Protein tyrosine phosphatase, receptor type Z1 7 121873089-122062036 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA015103, CAB025106, HPA071024 Enhanced Supported Supported Cytosol Urothelial cancer:9.36e-4 (unfavourable) Tissue enriched Tissue enriched 9 cerebral cortex: 257.9 skin: 30.1 Group enriched 12 AF22: 420.6;NTERA-2: 119.0;WM-115: 185.9 +TAF6 MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85 ENSG00000106290 TATA-box binding protein associated factor 6 7 100107070-100119841 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA006566 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:6.06e-5 (unfavourable) Expressed in all Expressed in all testis: 62.4 Expressed in all +WASL N-WASP, NWASP, WASPB ENSG00000106299 Wiskott-Aldrich syndrome like 7 123681935-123749067 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005399, HPA005750 Supported Approved Nucleoli
Cytosol Renal cancer:4.51e-8 (favourable), Pancreatic cancer:5.30e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 73.8 Expressed in all +HYAL4 ENSG00000106302 Hyaluronoglucosaminidase 4 7 123828983-123877478 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029453 Uncertain Tissue enriched Tissue enhanced placenta: 5.9;testis: 4.0 skin,spleen: 1.1 Cell line enhanced BEWO: 3.5;CAPAN-2: 5.2;RT4: 11.2 +SPAM1 HYAL5, PH-20, SPAG15 ENSG00000106304 Sperm adhesion molecule 1 7 123925237-123971414 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017984 Enhanced Not detected Tissue enriched 66 testis: 30.2 duodenum,small intestine: 0.4 Not detected +AIMP2 JTV-1, JTV1, p38, PRO0992 ENSG00000106305 Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 7 6009245-6023834 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019098, HPA020057 Supported Approved Cytosol Renal cancer:1.38e-5 (favourable), Urothelial cancer:3.09e-4 (unfavourable), Head and neck cancer:3.69e-4 (unfavourable) Expressed in all Expressed in all testis: 64.3 Expressed in all +TFR2 HFE3, TFRC2 ENSG00000106327 Transferrin receptor 2 7 100620416-100642779 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA011937, CAB016255 Enhanced Liver cancer:2.48e-4 (favourable) Tissue enriched Tissue enriched 11 liver: 155.5 bone marrow: 13.9 Group enriched 14 HEL: 62.3;HMC-1: 81.2;K-562: 58.4 +FSCN3 ENSG00000106328 Fascin actin-bundling protein 3 7 127591409-127602144 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 245 testis: 105.7 skin: 0.4 Not detected +MOSPD3 CDS3, NET30 ENSG00000106330 Motile sperm domain containing 3 7 100612102-100615384 Predicted membrane proteins Evidence at protein level HPA041137, HPA048240 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 29.6 Expressed in all +PAX4 MODY9 ENSG00000106331 Paired box 4 7 127610292-127618114 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level Not detected Tissue enhanced duodenum: 1.0;rectum: 1.1 small intestine,testis: 0.6 Cell line enriched 73 SCLC-21H: 15.3 +PCOLCE PCPE, PCPE1 ENSG00000106333 Procollagen C-endopeptidase enhancer 7 100602177-100608175 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB017623, HPA042927 Approved Approved Golgi apparatus
Vesicles Renal cancer:1.68e-5 (unfavourable), Melanoma:9.76e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 216.8 gallbladder: 145.9 Cell line enhanced ASC TERT1: 496.8;BJ hTERT+: 447.9;HSkMC: 595.6;SH-SY5Y: 617.5;U-2197: 961.3 +FBXO24 FBX24 ENSG00000106336 F-box protein 24 7 100583982-100601117 Predicted intracellular proteins Evidence at protein level HPA050951 Enhanced Mixed Tissue enriched 36 testis: 71.4 ovary: 1.9 Cell line enhanced U-2 OS: 2.7 +PPP1R17 C7orf16, GSBS ENSG00000106341 Protein phosphatase 1 regulatory subunit 17 7 31686715-31708455 Predicted intracellular proteins Evidence at protein level HPA047819, HPA073123 Supported Supported Nucleoplasm Tissue enhanced Group enriched 5 adrenal gland: 4.8;cerebral cortex: 2.6;testis: 1.1 lung: 0.5 Group enriched 225 NTERA-2: 33.8;SCLC-21H: 120.1 +RBM28 FLJ10377 ENSG00000106344 RNA binding motif protein 28 7 128297685-128343908 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019058, HPA026672, HPA031519 Enhanced Enhanced Nucleoli Liver cancer:2.72e-11 (unfavourable), Endometrial cancer:2.94e-4 (unfavourable), Melanoma:6.44e-4 (unfavourable) Expressed in all Expressed in all testis: 26.9 Expressed in all +USP42 FLJ12697 ENSG00000106346 Ubiquitin specific peptidase 42 7 6104884-6161564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006752, HPA064800 Uncertain Approved Nucleus Expressed in all Tissue enhanced testis: 27.8 parathyroid gland: 8.8 Expressed in all +IMPDH1 LCA11, RP10, sWSS2608 ENSG00000106348 Inosine monophosphate dehydrogenase 1 7 128392277-128410252 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA001400 Approved Supported Cytosol
Rods & Rings Renal cancer:1.78e-12 (unfavourable), Liver cancer:1.12e-7 (unfavourable), Urothelial cancer:3.72e-5 (unfavourable), Glioma:1.17e-4 (unfavourable), Cervical cancer:3.87e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 47.2 Expressed in all +AGFG2 HRBL, RABR ENSG00000106351 ArfGAP with FG repeats 2 7 100539211-100568219 Predicted intracellular proteins Evidence at protein level HPA019689 Enhanced Renal cancer:1.03e-6 (favourable), Pancreatic cancer:9.64e-4 (favourable) Expressed in all Tissue enriched 6 salivary gland: 127.1 skin: 22.8 Expressed in all +LSM5 YER146W ENSG00000106355 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated 7 32485332-32495283 Predicted intracellular proteins Evidence at protein level HPA019054 Uncertain Liver cancer:7.53e-5 (unfavourable), Renal cancer:1.84e-4 (unfavourable) Expressed in all Expressed in all breast: 77.7 Expressed in all +SERPINE1 PAI, PAI1, PLANH1 ENSG00000106366 Serpin family E member 1 7 101127089-101139266 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA050039, CAB068501 Uncertain Approved Cytosol Renal cancer:5.88e-8 (unfavourable), Stomach cancer:3.27e-6 (unfavourable), Lung cancer:4.41e-6 (unfavourable), Head and neck cancer:2.84e-5 (unfavourable), Colorectal cancer:2.82e-4 (unfavourable), Cervical cancer:5.01e-4 (unfavourable), Urothelial cancer:5.51e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 580.3;placenta: 600.2 adipose tissue: 215.8 Cell line enhanced TIME: 8072.1;U-138 MG: 4492.2;U-251 MG: 3465.4 +AP1S1 AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2 ENSG00000106367 Adaptor related protein complex 1 sigma 1 subunit 7 101154397-101161596 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060945 Supported Supported Golgi apparatus
Vesicles Expressed in all Expressed in all cerebral cortex: 107.0 Expressed in all +MOGAT3 DC7, DGAT2L2, MGAT3 ENSG00000106384 Monoacylglycerol O-acyltransferase 3 7 101195007-101201021 Enzymes, Predicted membrane proteins Evidence at protein level HPA011940 Uncertain Approved Centrosome Tissue enhanced Group enriched 6 colon: 11.3;duodenum: 30.4;rectum: 11.9;small intestine: 33.6 liver: 3.4 Cell line enhanced CACO-2: 2.9;Hep G2: 8.1 +C1GALT1 C1GALT, T-synthase ENSG00000106392 Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 7 7156934-7248651 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011294, HPA012819 Enhanced Approved Nuclear bodies
Cytosol Liver cancer:1.42e-5 (unfavourable), Cervical cancer:1.04e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 95.0 Expressed in all +PLOD3 LH3 ENSG00000106397 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 7 101205977-101218420 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001236 Uncertain Cervical cancer:1.91e-5 (unfavourable), Colorectal cancer:3.26e-4 (unfavourable) Expressed in all Expressed in all placenta: 48.1 Expressed in all +RPA3 REPA3 ENSG00000106399 Replication protein A3 7 7636518-7718607 Predicted intracellular proteins Evidence at protein level HPA005708 Approved Liver cancer:5.16e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.7 Expressed in all +ZNHIT1 CG1I, H_DJ0747G18.14, ZNFN4A1 ENSG00000106400 Zinc finger HIT-type containing 1 7 101217668-101224190 Predicted intracellular proteins Evidence at protein level HPA019043 Uncertain Approved Nucleoplasm Expressed in all Expressed in all liver: 50.6 Expressed in all +CLDN15 ENSG00000106404 Claudin 15 7 101232092-101238820 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Renal cancer:5.31e-5 (unfavourable), Pancreatic cancer:2.56e-4 (favourable), Urothelial cancer:3.30e-4 (favourable) Expressed in all Group enriched 16 duodenum: 241.3;small intestine: 183.5 spleen: 13.3 Expressed in all +NOBOX OG2, Og2x ENSG00000106410 NOBOX oogenesis homeobox 7 144397240-144410227 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enhanced Not detected testis: 0.7 Not detected +GLCCI1 FAM117C, GIG18, TSSN1 ENSG00000106415 Glucocorticoid induced 1 7 7968794-8094272 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001674, HPA005987 Approved Uncertain Nucleoli Expressed in all Mixed thyroid gland: 28.1 Cell line enhanced U-266/70: 66.1 +MYL10 MGC3479, MYLC2PL, PLRLC ENSG00000106436 Myosin light chain 10 7 101613325-101629296 Predicted intracellular proteins Evidence at protein level HPA019763 Uncertain Uncertain Microtubules Tissue enhanced Not detected cervix, uterine,placenta: 0.7 Cell line enhanced PC-3: 1.7;RH-30: 2.3 +PHF14 KIAA0783 ENSG00000106443 PHD finger protein 14 7 10973872-11169630 Predicted intracellular proteins Evidence at protein level HPA000538, HPA017376 Supported Approved Nucleus
Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 20.8 Expressed in all +NRF1 ALPHA-PAL, EWG ENSG00000106459 Nuclear respiratory factor 1 7 129611714-129757082 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029329 Approved Supported Nucleoplasm
Cytosol Liver cancer:6.02e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 20.9 Expressed in all +TMEM106B FLJ11273, MGC33727 ENSG00000106460 Transmembrane protein 106B 7 12211241-12243367 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058342 Approved Supported Endosomes
Lysosomes Expressed in all Expressed in all thyroid gland: 64.9 Expressed in all +EZH2 ENX-1, EZH1, KMT6, KMT6A ENSG00000106462 Enhancer of zeste 2 polycomb repressive complex 2 subunit 7 148807383-148884321 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB009589 Enhanced Supported Nucleoplasm Renal cancer:8.18e-12 (unfavourable), Liver cancer:2.11e-6 (unfavourable), Melanoma:1.96e-4 (unfavourable), Stomach cancer:6.97e-4 (favourable) Expressed in all Tissue enhanced testis: 50.5 bone marrow: 30.0 Expressed in all +CEP41 DKFZp762H1311, FLJ22445, JBTS15, TSGA14 ENSG00000106477 Centrosomal protein 41 7 130393771-130442433 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024090 Uncertain Colorectal cancer:4.54e-4 (favourable) Expressed in all Tissue enhanced testis: 80.5 salivary gland: 18.1 Mixed +ZNF862 ENSG00000106479 Zinc finger protein 862 7 149838367-149867479 Predicted intracellular proteins Evidence at protein level HPA024154 Uncertain Approved Mitochondria Urothelial cancer:8.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 23.7 Mixed +SFRP4 FRP-4, frpHE ENSG00000106483 Secreted frizzled related protein 4 7 37905932-38025695 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA009712, HPA050585 Enhanced Renal cancer:1.36e-5 (unfavourable) Expressed in all Group enriched 5 cervix, uterine: 935.5;endometrium: 776.1;fallopian tube: 338.6 smooth muscle: 130.5 Cell line enhanced ASC diff: 6.5;HSkMC: 2.7;U-937: 2.9 +MEST PEG1 ENSG00000106484 Mesoderm specific transcript 7 130486171-130506296 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005623 Approved Golgi apparatus
Cytosol Renal cancer:6.20e-5 (unfavourable) Expressed in all Tissue enriched 8 placenta: 1087.6 adipose tissue: 131.8 Cell line enriched 5 AN3-CA: 10976.9 +MEOX2 GAX, MOX2 ENSG00000106511 Mesenchyme homeobox 2 7 15611212-15686812 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053793 Enhanced Tissue enriched Tissue enhanced adipose tissue: 28.5;placenta: 57.7 lung: 10.8 Cell line enhanced AN3-CA: 217.5;SCLC-21H: 37.0;U-138 MG: 58.7 +ANKMY2 DKFZP564O043, ZMYND20 ENSG00000106524 Ankyrin repeat and MYND domain containing 2 7 16599776-16645817 Predicted intracellular proteins Evidence at protein level HPA044900, HPA050447, HPA067100 Approved Nucleoplasm
Cytosol Renal cancer:1.05e-7 (favourable) Expressed in all Expressed in all thyroid gland: 34.5 Expressed in all +ACTR3C ARP11 ENSG00000106526 ARP3 actin-related protein 3 homolog C 7 150243916-150323725 Predicted intracellular proteins Evidence at transcript level HPA055957 Uncertain Mixed Tissue enriched 6 parathyroid gland: 87.3 adrenal gland: 15.8 Cell line enhanced CAPAN-2: 27.5;RT4: 21.3;SiHa: 18.9 +POU6F2 RPF-1 ENSG00000106536 POU class 6 homeobox 2 7 38977998-39493095 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Tissue enhanced cerebral cortex: 3.1;placenta: 1.8 gallbladder,testis: 1.2 Cell line enhanced EFO-21: 3.0;NTERA-2: 3.1;T-47d: 5.3;U-266/70: 4.7;U-266/84: 5.5 +TSPAN13 NET-6, TM4SF13 ENSG00000106537 Tetraspanin 13 7 16753535-16784536 Predicted membrane proteins Evidence at protein level HPA007426 Uncertain Approved Nucleus Glioma:5.27e-5 (unfavourable), Ovarian cancer:2.20e-4 (favourable), Renal cancer:2.43e-4 (unfavourable), Liver cancer:2.94e-4 (unfavourable) Expressed in all Expressed in all lung: 246.2 Cell line enhanced SCLC-21H: 223.6;SK-BR-3: 207.6;T-47d: 488.1 +RARRES2 HP10433, TIG2 ENSG00000106538 Retinoic acid receptor responder 2 7 150338317-150341674 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA049359 Uncertain Cytosol Renal cancer:6.83e-4 (unfavourable), Glioma:6.90e-4 (unfavourable) Expressed in all Tissue enhanced adrenal gland: 1522.8 parathyroid gland: 915.7 Group enriched 8 AF22: 120.4;Hep G2: 124.8;HHSteC: 130.5;NTERA-2: 372.4 +AGR2 AG2, HAG-2, PDIA17, XAG-2 ENSG00000106541 Anterior gradient 2, protein disulphide isomerase family member 7 16791811-16833433 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007912 Enhanced Approved Cytosol Renal cancer:8.79e-5 (unfavourable), Liver cancer:1.15e-4 (unfavourable) Mixed Tissue enhanced rectum: 1322.0;stomach: 1307.3 cervix, uterine: 939.5 Cell line enhanced A549: 239.4;RPTEC TERT1: 465.3;RT4: 298.0;T-47d: 1243.5 +AHR bHLHe76 ENSG00000106546 Aryl hydrocarbon receptor 7 17298622-17346152 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005072, HPA029722, HPA029723 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Mixed lung: 56.4 Mixed +CHCHD3 FLJ20420, Mic19, MINOS3, PPP1R22 ENSG00000106554 Coiled-coil-helix-coiled-coil-helix domain containing 3 7 132784868-133082088 Predicted intracellular proteins Evidence at protein level HPA042935 Enhanced Supported Mitochondria Renal cancer:1.15e-4 (favourable), Liver cancer:3.25e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 121.2 Expressed in all +GIMAP2 DKFZp586D0824, HIMAP2, IAN12, IMAP2 ENSG00000106560 GTPase, IMAP family member 2 7 150685697-150693641 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013589 Approved Renal cancer:1.29e-4 (unfavourable), Breast cancer:3.50e-4 (favourable) Expressed in all Mixed lymph node: 88.0 Cell line enhanced HUVEC TERT2: 52.1;MOLT-4: 63.1;REH: 30.9 +TMEM176B LR8, MS4B2 ENSG00000106565 Transmembrane protein 176B 7 150791285-150801360 Predicted membrane proteins Evidence at protein level HPA047509 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Expressed in all Expressed in all liver: 845.2 Group enriched 13 HSkMC: 462.2;THP-1: 144.5 +GLI3 ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV ENSG00000106571 GLI family zinc finger 3 7 41960950-42237870 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005534 Approved Mixed Mixed endometrium: 15.9 Cell line enhanced AF22: 44.3;WM-115: 32.9 +PSMA2 HC3, MU, PMSA2 ENSG00000106588 Proteasome subunit alpha 2 7 42916857-42932223 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008188 Uncertain Ovarian cancer:6.73e-5 (favourable), Liver cancer:1.29e-4 (unfavourable) Expressed in all Expressed in all liver: 165.2 Expressed in all +MRPL32 bMRP-59b, HSPC283, L32mt, MRP-L32 ENSG00000106591 Mitochondrial ribosomal protein L32 7 42932200-42948958 Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA048965 Uncertain Expressed in all Expressed in all adrenal gland: 72.1 Expressed in all +COA1 C7orf44, FLJ10803, MITRAC15 ENSG00000106603 Cytochrome c oxidase assembly factor 1 homolog 7 43608456-43729717 Predicted membrane proteins Evidence at protein level HPA011944 Approved Supported Mitochondria Liver cancer:7.84e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 38.6 Expressed in all +BLVRA BLVR ENSG00000106605 Biliverdin reductase A 7 43758680-43807342 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019709, HPA042865, HPA054322 Approved Supported Cytosol Lung cancer:8.65e-4 (favourable) Expressed in all Expressed in all epididymis: 158.1 Mixed +URGCP DKFZp666G166, DKFZp686O0457, FLJ20654, KIAA1507, URG4 ENSG00000106608 Upregulator of cell proliferation 7 43875894-43926411 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019879, HPA020134, HPA029468 Approved Supported Cytosol Renal cancer:1.90e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 34.6 Expressed in all +TMEM248 C7orf42, FLJ10099, FLJ13090 ENSG00000106609 Transmembrane protein 248 7 66921225-66958551 Predicted membrane proteins Evidence at protein level HPA016495 Uncertain Approved Vesicles Expressed in all Expressed in all parathyroid gland: 93.8 Expressed in all +RHEB RHEB2 ENSG00000106615 Ras homolog enriched in brain 7 151466012-151520120 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB019436 Uncertain Liver cancer:9.08e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 207.2 Expressed in all +PRKAG2 AAKG, AAKG2, CMH6, H91620p, WPWS ENSG00000106617 Protein kinase AMP-activated non-catalytic subunit gamma 2 7 151556111-151877125 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004246, CAB018641 Uncertain Approved Nucleoplasm Expressed in all Expressed in all heart muscle: 81.8 Mixed +AEBP1 ACLP ENSG00000106624 AE binding protein 1 7 44104361-44114562 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB009966, HPA047724, HPA063595, HPA064970 Enhanced Supported Nucleoplasm
Vesicles
Cytosol Renal cancer:9.31e-9 (unfavourable), Glioma:1.10e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 300.4 Cell line enhanced BJ: 163.5;fHDF/TERT166: 162.3;WM-115: 116.5 +POLD2 ENSG00000106628 DNA polymerase delta 2, accessory subunit 7 44114681-44124358 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026745 Approved Enhanced Nucleoplasm Expressed in all Expressed in all fallopian tube: 122.1 Expressed in all +MYL7 MYL2A, MYLC2A ENSG00000106631 Myosin light chain 7 7 44138864-44141332 Predicted intracellular proteins Evidence at protein level HPA013331, CAB033884, HPA039262 Enhanced Tissue enriched Tissue enriched 1272 heart muscle: 8172.3 breast: 6.4 Group enriched 26 BEWO: 34.4;CACO-2: 103.4 +GCK HK4, MODY2 ENSG00000106633 Glucokinase 7 44144271-44198170 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007034, HPA007093 Approved Approved Golgi apparatus
Cytosol Tissue enhanced Mixed cerebral cortex: 2.5 Cell line enriched 6 SCLC-21H: 7.7 +BCL7B ENSG00000106635 BCL tumor suppressor 7B 7 73536356-73558002 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049943, HPA058069 Approved Approved Nucleoplasm Renal cancer:4.38e-4 (favourable) Expressed in all Expressed in all bone marrow: 24.7 Expressed in all +YKT6 ENSG00000106636 YKT6 v-SNARE homolog (S. cerevisiae) 7 44200968-44214294 Predicted intracellular proteins Evidence at protein level HPA030817, HPA030818 Approved Approved Mitochondria
Cytosol Liver cancer:1.02e-4 (unfavourable), Head and neck cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 61.8 Expressed in all +TBL2 DKFZP43N024, WBSCR13, WS-betaTRP ENSG00000106638 Transducin beta like 2 7 73568932-73578791 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007477, HPA051533 Supported Cytosol Renal cancer:1.88e-5 (unfavourable), Head and neck cancer:4.93e-4 (unfavourable) Expressed in all Tissue enriched 6 testis: 83.8 parathyroid gland: 13.0 Expressed in all +GALNTL5 GalNAc-T5L, GALNT15 ENSG00000106648 Polypeptide N-acetylgalactosaminyltransferase-like 5 7 151956379-152019934 Disease related genes, Predicted membrane proteins Evidence at protein level HPA011140 Enhanced Not detected Tissue enriched 14 testis: 11.1 cerebral cortex: 0.8 Not detected +CLIP2 CLIP, CLIP-115, CYLN2, KIAA0291, WBSCR3, WBSCR4, WSCR3, WSCR4 ENSG00000106665 CAP-Gly domain containing linker protein 2 7 74289475-74405943 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020430, CAB020767 Enhanced Endometrial cancer:5.35e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 75.8 ovary: 21.0 Mixed +EIF4H KIAA0038, WBSCR1, WSCR1 ENSG00000106682 Eukaryotic translation initiation factor 4H 7 74174245-74197101 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030542 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Head and neck cancer:2.15e-4 (unfavourable), Glioma:5.65e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 254.3 Expressed in all +LIMK1 LIMK ENSG00000106683 LIM domain kinase 1 7 74082933-74122525 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028064, HPA028516 Approved Supported Nuclear speckles
Cytosol Renal cancer:6.63e-8 (unfavourable), Liver cancer:7.79e-6 (unfavourable), Colorectal cancer:4.95e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.5 Expressed in all +SPATA6L C9orf68, FLJ10058 ENSG00000106686 Spermatogenesis associated 6 like 9 4553386-4666674 Predicted intracellular proteins Evidence at protein level HPA039585 Enhanced Mixed Tissue enhanced fallopian tube: 5.8;testis: 6.4 gallbladder,lung: 2.3 Cell line enhanced BEWO: 1.3;CAPAN-2: 2.1;HDLM-2: 1.3;RPTEC TERT1: 1.3;SCLC-21H: 1.8 +SLC1A1 EAAC1, EAAT3 ENSG00000106688 Solute carrier family 1 member 1 9 4490444-4587469 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB015466, HPA020086 Approved Renal cancer:2.86e-8 (favourable) Expressed in all Tissue enhanced small intestine: 71.2 epididymis: 54.5 Cell line enhanced HDLM-2: 65.4;RPTEC TERT1: 50.1 +LHX2 hLhx2, LH-2 ENSG00000106689 LIM homeobox 2 9 124001670-124033301 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA000838 Supported Approved Nucleoplasm Cervical cancer:9.52e-4 (favourable) Group enriched Tissue enriched 11 cerebral cortex: 56.3 placenta: 5.1 Cell line enhanced AN3-CA: 22.0;HAP1: 24.5;NTERA-2: 29.4 +FKTN FCMD, LGMD2M ENSG00000106692 Fukutin 9 105558130-105641118 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA012820 Approved Urothelial cancer:3.02e-4 (unfavourable), Liver cancer:9.42e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 17.3 Expressed in all +FSD1L CCDC10, CSDUFD1, FSD1CL, FSD1NL ENSG00000106701 Fibronectin type III and SPRY domain containing 1 like 9 105447796-105552433 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035138 Approved Approved Plasma membrane
Actin filaments Mixed Tissue enhanced cerebral cortex: 17.8 testis: 13.5 Mixed +CNTNAP3 CASPR3, CNTNAP3A, FLJ14195, KIAA1714 ENSG00000106714 Contactin associated protein-like 3 9 39072767-39288315 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA047731 Uncertain Mixed Mixed esophagus: 8.2 Cell line enhanced A549: 17.0;AF22: 22.2;WM-115: 37.4 +SPIN1 SPIN, TDRD24 ENSG00000106723 Spindlin 1 9 88388419-88478694 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000162, HPA068784 Uncertain Supported Nucleoplasm Renal cancer:8.69e-6 (favourable) Expressed in all Expressed in all endometrium: 101.8 Mixed +NMRK1 bA235O14.2, C9orf95, FLJ20559, NRK1 ENSG00000106733 Nicotinamide riboside kinase 1 9 75060573-75088217 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049795 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:3.70e-6 (favourable), Renal cancer:5.60e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 120.8 Cell line enhanced HDLM-2: 70.8 +TMEM245 C9orf5, CG-2 ENSG00000106771 Transmembrane protein 245 9 109015152-109119945 Predicted membrane proteins Evidence at protein level HPA023892 Approved Approved Plasma membrane
Cytosol Renal cancer:4.46e-9 (favourable) Expressed in all Expressed in all thyroid gland: 124.0 Expressed in all +PRUNE2 A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367 ENSG00000106772 Prune homolog 2 9 76611376-76906087 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA022470, HPA031079 Uncertain Renal cancer:1.37e-6 (favourable) Mixed Mixed seminal vesicle: 89.8 Cell line enhanced LHCN-M2: 69.0;RH-30: 68.7 +MEGF9 EGFL5 ENSG00000106780 Multiple EGF like domains 9 9 120600813-120714470 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA014319, HPA050238 Uncertain Approved Nucleus
Cytosol Renal cancer:5.48e-11 (favourable) Expressed in all Expressed in all thyroid gland: 47.2 Mixed +TRIM14 KIAA0129 ENSG00000106785 Tripartite motif containing 14 9 98069275-98119212 Predicted intracellular proteins Evidence at protein level HPA053217 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Mixed parathyroid gland: 37.6 Mixed +CORO2A IR10, WDR2 ENSG00000106789 Coronin 2A 9 98120975-98192640 Predicted intracellular proteins Evidence at protein level HPA041161, HPA041302 Enhanced Approved Plasma membrane
Cytosol Renal cancer:6.56e-4 (unfavourable) Mixed Mixed small intestine: 38.5 Cell line enhanced BEWO: 64.3;SK-BR-3: 33.9 +TGFBR1 ACVRLK4, ALK-5, ALK5, ESS1, MSSE ENSG00000106799 Transforming growth factor beta receptor 1 9 99104038-99154192 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002441, CAB031481, HPA056473 Uncertain Supported Vesicles
Plasma membrane Expressed in all Expressed in all placenta: 69.8 Expressed in all +SEC61B ENSG00000106803 Sec61 translocon beta subunit 9 99222064-99230615 Predicted membrane proteins, Transporters Evidence at protein level HPA049407 Approved Enhanced Endoplasmic reticulum Endometrial cancer:1.26e-5 (favourable) Expressed in all Expressed in all epididymis: 339.1 Expressed in all +C5 C5a, C5b, CPAMD4 ENSG00000106804 Complement C5 9 120952335-121050276 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA029339 Uncertain Liver cancer:9.43e-4 (favourable) Tissue enriched Tissue enriched 21 liver: 225.6 lung: 10.5 Cell line enhanced A549: 25.6;Hep G2: 20.6 +OGN mimecan, OIF, SLRR3A ENSG00000106809 Osteoglycin 9 92383967-92404696 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA013132 Approved Supported Endoplasmic reticulum Renal cancer:1.92e-4 (unfavourable), Urothelial cancer:2.03e-4 (unfavourable), Ovarian cancer:4.04e-4 (unfavourable) Mixed Tissue enhanced cervix, uterine: 374.3;parathyroid gland: 604.4 gallbladder: 276.4 Cell line enhanced ASC TERT1: 17.1;HSkMC: 8.0;MOLT-4: 27.9 +ASPN FLJ20129, PLAP1, SLRR1C ENSG00000106819 Asporin 9 92456205-92482506 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA008435, HPA024230 Approved Uncertain Nucleoplasm Renal cancer:1.64e-7 (unfavourable) Expressed in all Tissue enhanced endometrium: 115.6;smooth muscle: 161.0 gallbladder: 104.1 Cell line enhanced ASC TERT1: 11.2;BJ hTERT+: 4.6;HHSteC: 19.2 +ECM2 ENSG00000106823 Extracellular matrix protein 2 9 92493554-92536655 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA035347 Approved Renal cancer:4.09e-6 (unfavourable), Liver cancer:4.50e-5 (favourable) Expressed in all Mixed adipose tissue: 128.6 Cell line enhanced ASC diff: 13.1;ASC TERT1: 24.2;HSkMC: 26.7;hTCEpi: 30.9 +TLE4 E(spI), ESG, GRG4 ENSG00000106829 Transducin like enhancer of split 4 9 79571773-79726882 Predicted intracellular proteins Evidence at protein level HPA065357 Supported Nucleus Renal cancer:6.94e-4 (favourable) Expressed in all Expressed in all testis: 201.9 Cell line enhanced fHDF/TERT166: 131.2 +LHX6 LHX6.1 ENSG00000106852 LIM homeobox 6 9 122202577-122229626 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047854, HPA058319 Approved Uncertain Nucleoli fibrillar center
Plasma membrane Mixed Mixed cerebral cortex: 8.1 Cell line enhanced CACO-2: 10.9;NB-4: 11.6;PC-3: 11.4;U-87 MG: 9.4 +PTGR1 LTB4DH, ZADH3 ENSG00000106853 Prostaglandin reductase 1 9 111549722-111599855 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036724 Enhanced Renal cancer:5.53e-4 (favourable) Expressed in all Expressed in all small intestine: 315.8 Mixed +SUSD1 DKFZP761E1824 ENSG00000106868 Sushi domain containing 1 9 112040785-112175408 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA048554 Approved Approved Nucleoplasm Renal cancer:3.63e-6 (favourable) Expressed in all Mixed placenta: 21.5 Cell line enhanced HEL: 50.2 +AMBP EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI ENSG00000106927 Alpha-1-microglobulin/bikunin precursor 9 114060127-114078472 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001497, CAB069436 Approved Endometrial cancer:1.20e-4 (favourable) Tissue enriched Tissue enriched 23 liver: 5176.2 gallbladder: 230.0 Cell line enriched 113 Hep G2: 861.2 +AKNA KIAA1968 ENSG00000106948 AT-hook transcription factor 9 114334156-114394405 Predicted intracellular proteins Evidence at protein level HPA052367, HPA063993 Supported Nucleoplasm
Centrosome Endometrial cancer:2.14e-5 (favourable), Renal cancer:2.55e-5 (unfavourable), Cervical cancer:1.22e-4 (favourable), Head and neck cancer:1.25e-4 (favourable), Urothelial cancer:2.29e-4 (favourable) Expressed in all Mixed spleen: 95.6 Cell line enhanced HDLM-2: 81.7;MOLT-4: 67.8 +TNFSF8 CD153, CD30LG ENSG00000106952 Tumor necrosis factor superfamily member 8 9 114893343-114930595 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced lymph node: 34.4;tonsil: 26.7 appendix: 24.3 Group enriched 99 Daudi: 50.4;U-698: 39.7 +DNM1 DNM ENSG00000106976 Dynamin 1 9 128191655-128255248 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005920, HPA049910, HPA061801 Enhanced Supported Nucleoplasm Mixed Tissue enriched 14 cerebral cortex: 364.2 cervix, uterine: 25.6 Cell line enhanced A549: 114.8 +ENG CD105, END, HHT1, ORW, ORW1 ENSG00000106991 Endoglin 9 127815012-127854756 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB000096, HPA011862, HPA067440, CAB072873 Enhanced Liver cancer:5.62e-6 (favourable), Renal cancer:4.26e-4 (unfavourable), Head and neck cancer:6.61e-4 (favourable) Expressed in all Expressed in all spleen: 167.6 Cell line enhanced HUVEC TERT2: 402.6;TIME: 810.4 +AK1 ENSG00000106992 Adenylate kinase 1 9 127866480-127877743 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006456, CAB009893 Enhanced Supported Cytosol Stomach cancer:7.31e-4 (favourable) Expressed in all Expressed in all fallopian tube: 774.9 Mixed +CDC37L1 CDC37B, FLJ20639, HARC ENSG00000106993 Cell division cycle 37 like 1 9 4679559-4708398 Predicted intracellular proteins Evidence at protein level HPA021175 Approved Supported Cytosol Renal cancer:2.66e-7 (favourable) Expressed in all Expressed in all liver: 28.5 Expressed in all +RLN2 bA12D24.1.1, bA12D24.1.2, H2, RLXH2 ENSG00000107014 Relaxin 2 9 5299868-5304969 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced fallopian tube: 8.1 prostate: 6.0 Cell line enhanced HEL: 19.0;T-47d: 5.6;U-266/84: 6.9 +RLN1 H1 ENSG00000107018 Relaxin 1 9 5334969-5339873 Plasma proteins, Predicted secreted proteins Evidence at transcript level Tissue enriched Tissue enriched 64 prostate: 40.0 testis: 0.6 Cell line enhanced HEL: 1.0 +PLGRKT AD025, C9orf46, FLJ14688, MDS030, Plg-RKT ENSG00000107020 Plasminogen receptor with a C-terminal lysine 9 5357973-5437878 Predicted intracellular proteins Evidence at protein level HPA008214, HPA011144 Enhanced Uncertain Mitochondria Renal cancer:5.09e-5 (favourable), Breast cancer:5.56e-4 (favourable) Expressed in all Expressed in all rectum: 55.2 Cell line enhanced HDLM-2: 245.6 +TBC1D13 FLJ10743 ENSG00000107021 TBC1 domain family member 13 9 128787204-128810432 Predicted intracellular proteins Evidence at protein level HPA045865 Approved Approved Nucleoli Renal cancer:1.58e-7 (favourable), Pancreatic cancer:3.14e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 47.2 Expressed in all +RIC1 bA207C16.1, KIAA1432 ENSG00000107036 RIC1 homolog, RAB6A GEF complex partner 1 9 5629025-5776557 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051578 Supported Expressed in all Expressed in all testis: 21.4 Expressed in all +KDM4C GASC1, JMJD2C, KIAA0780, TDRD14C ENSG00000107077 Lysine demethylase 4C 9 6720863-7175648 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA069357 Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 36.0 Expressed in all +DOCK8 FLJ00026, FLJ00152, FLJ00346, ZIR8 ENSG00000107099 Dedicator of cytokinesis 8 9 214854-465259 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003218 Enhanced Approved Nucleoplasm
Centrosome
Mitochondria
Cytosol Urothelial cancer:6.89e-6 (favourable), Renal cancer:9.21e-6 (favourable) Expressed in all Mixed spleen: 62.1 Cell line enhanced HL-60: 42.1;NB-4: 52.6;REH: 56.3;RT4: 42.9;THP-1: 105.5 +KANK1 ANKRD15, KANK, KIAA0172 ENSG00000107104 KN motif and ankyrin repeat domains 1 9 470291-746106 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005539, HPA056090 Approved Supported Plasma membrane Expressed in all Mixed smooth muscle: 55.8 Mixed +ELAVL2 HEL-N1, HuB ENSG00000107105 ELAV like RNA binding protein 2 9 23690104-23826337 Predicted intracellular proteins Evidence at protein level CAB022222, HPA063001 Enhanced Approved Nucleoplasm
Cytosol Tissue enhanced Group enriched 32 cerebral cortex: 37.9;testis: 80.3 adrenal gland: 1.8 Cell line enhanced AF22: 36.8;SCLC-21H: 145.6 +NCS1 FREQ, NCS-1 ENSG00000107130 Neuronal calcium sensor 1 9 130172578-130237304 Predicted intracellular proteins Evidence at protein level CAB018587, HPA019713 Enhanced Supported Enhanced Plasma membrane Liver cancer:1.11e-4 (unfavourable), Breast cancer:5.40e-4 (unfavourable), Thyroid cancer:8.25e-4 (unfavourable), Endometrial cancer:8.69e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 178.1 seminal vesicle: 92.3 Mixed +TESK1 ENSG00000107140 Testis-specific kinase 1 9 35605305-35610041 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:9.68e-4 (unfavourable) Expressed in all Expressed in all testis: 46.2 Expressed in all +KCNT1 KCa4.1, KIAA1422, SLACK, Slo2.2 ENSG00000107147 Potassium sodium-activated channel subfamily T member 1 9 135702185-135795508 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA059880 Uncertain Tissue enhanced Group enriched 5 cerebral cortex: 11.6;ovary: 3.9;skeletal muscle: 3.8;spleen: 6.8 testis: 1.2 Cell line enhanced RPMI-8226: 1.2;SCLC-21H: 3.0 +CA9 CAIX, MN ENSG00000107159 Carbonic anhydrase 9 9 35673856-35681159 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB005100, CAB017107, HPA055207 Enhanced Enhanced Plasma membrane
Cytosol Renal cancer:2.22e-7 (unfavourable), Liver cancer:1.71e-5 (unfavourable), Testis cancer:9.50e-4 (favourable) Mixed Tissue enhanced gallbladder: 36.0;stomach: 93.6 small intestine: 14.5 Group enriched 11 A-431: 152.1;HDLM-2: 84.3;U-87 MG: 337.9 +FUBP3 FBP3 ENSG00000107164 Far upstream element binding protein 3 9 130578965-130638352 Predicted intracellular proteins Evidence at protein level HPA047658, HPA058392 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:4.39e-5 (favourable), Lung cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 71.7 Expressed in all +TYRP1 b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP ENSG00000107165 Tyrosinase related protein 1 9 12685439-12710290 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA000937, CAB002520 Enhanced Supported Vesicles Tissue enriched Group enriched 6 heart muscle: 40.2;skin: 169.1 kidney: 17.0 Cell line enriched 51 SK-MEL-30: 1084.9 +CREB3 Luman, LZIP, sLZIP ENSG00000107175 CAMP responsive element binding protein 3 9 35732335-35737004 Predicted membrane proteins, Transcription factors Evidence at protein level HPA030978 Supported Cytosol Renal cancer:3.77e-5 (favourable), Ovarian cancer:5.40e-4 (favourable), Liver cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all prostate: 55.8 Expressed in all +RGP1 KIAA0258 ENSG00000107185 RGP1 homolog, RAB6A GEF complex partner 1 9 35749287-35758575 Predicted intracellular proteins Evidence at protein level HPA020414, HPA021085 Approved Enhanced Plasma membrane
Cytosol Renal cancer:8.55e-13 (favourable), Liver cancer:7.09e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.9 Expressed in all +MPDZ MUPP1 ENSG00000107186 Multiple PDZ domain crumbs cell polarity complex component 9 13105704-13279590 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013512, HPA020255, HPA026686 Uncertain Pancreatic cancer:7.40e-4 (favourable), Liver cancer:8.68e-4 (favourable) Expressed in all Mixed liver: 44.3 Cell line enhanced AF22: 57.0 +LHX3 ENSG00000107187 LIM homeobox 3 9 136196250-136205109 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Not detected cerebral cortex: 0.4 Cell line enhanced U-266/70: 1.0 +DDX58 DKFZp434J1111, FLJ13599, RIG-I ENSG00000107201 DExD/H-box helicase 58 9 32455705-32526324 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB012643, HPA047193 Uncertain Supported Cytosol Renal cancer:4.66e-4 (unfavourable), Endometrial cancer:5.46e-4 (unfavourable) Expressed in all Expressed in all spleen: 19.8 Group enriched 6 BJ hTERT+ SV40 Large T+: 118.2;BJ hTERT+ SV40 Large T+ RasG12V: 128.1 +EDF1 CFAP280, EDF-1 ENSG00000107223 Endothelial differentiation related factor 1 9 136862119-136866286 Predicted intracellular proteins Evidence at protein level HPA035642 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all small intestine: 557.4 Expressed in all +PIP5K1B MSS4, STM7 ENSG00000107242 Phosphatidylinositol-4-phosphate 5-kinase type 1 beta 9 68705414-69009176 Enzymes, Predicted intracellular proteins Evidence at protein level HPA009687 Uncertain Approved Nucleus
Vesicles Renal cancer:1.03e-9 (favourable) Mixed Mixed testis: 50.3 Cell line enhanced AF22: 47.6;HEL: 16.8;U-266/70: 14.2 +GLIS3 MGC33662, ZNF515 ENSG00000107249 GLIS family zinc finger 3 9 3824127-4348392 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA056426 Approved Supported Nucleoplasm Mixed Tissue enhanced thyroid gland: 34.9 fallopian tube: 16.6 Cell line enhanced BJ hTERT+: 19.2;HSkMC: 25.2 +BAG1 ENSG00000107262 BCL2 associated athanogene 1 9 33247820-33264720 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB002486, HPA018121 Enhanced Supported Nucleoplasm Renal cancer:2.22e-16 (favourable) Expressed in all Expressed in all parathyroid gland: 174.5 Expressed in all +RAPGEF1 C3G, GRF2 ENSG00000107263 Rap guanine nucleotide exchange factor 1 9 131576770-131740074 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006426 Approved Renal cancer:1.18e-5 (favourable) Expressed in all Expressed in all placenta: 80.8 Expressed in all +NPDC1 CAB-, CAB1, DKFZp586J0523 ENSG00000107281 Neural proliferation, differentiation and control 1 9 137039470-137046203 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008189 Approved Approved Nucleus
Cytosol Colorectal cancer:2.01e-5 (unfavourable), Endometrial cancer:6.19e-5 (favourable), Pancreatic cancer:3.18e-4 (favourable) Expressed in all Expressed in all prostate: 124.2 Mixed +APBA1 D9S411E, MINT1, X11 ENSG00000107282 Amyloid beta precursor protein binding family A member 1 9 69427530-69672306 Predicted intracellular proteins Evidence at protein level HPA061287 Supported Golgi apparatus Mixed Tissue enhanced cerebral cortex: 18.4 parathyroid gland: 11.8 Cell line enhanced HAP1: 18.1;SCLC-21H: 7.9;U-138 MG: 7.0 +SETX ALS4, AOA2, KIAA0625, SCAR1 ENSG00000107290 Senataxin 9 132261356-132354985 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024105, HPA057269 Approved Supported Nucleus
Cytokinetic bridge Expressed in all Expressed in all testis: 58.3 Expressed in all +SH3GL2 CNSA2, EEN-B1, SH3D2A, SH3P4 ENSG00000107295 SH3 domain containing GRB2 like 2, endophilin A1 9 17579082-17797129 Predicted intracellular proteins Evidence at protein level CAB010056, HPA026685, HPA063573 Enhanced Supported Approved Microtubules
Cytokinetic bridge
Mitotic spindle Renal cancer:6.68e-12 (favourable) Tissue enhanced Tissue enriched 10 cerebral cortex: 170.1 kidney: 17.5 Cell line enhanced HeLa: 14.7;RT4: 34.0;SCLC-21H: 31.7 +PTGDS L-PGDS, PGDS ENSG00000107317 Prostaglandin D2 synthase 9 136975092-136981742 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004938, CAB009916 Approved Supported Nucleoplasm Renal cancer:1.19e-7 (unfavourable) Expressed in all Expressed in all testis: 2581.3 Group enriched 7 HHSteC: 440.4;HSkMC: 186.3 +ABCA2 ABC2 ENSG00000107331 ATP binding cassette subfamily A member 2 9 137007227-137028922 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA042886 Approved Expressed in all Tissue enriched 6 cerebral cortex: 97.9 thyroid gland: 17.1 Cell line enhanced T-47d: 63.1 +SHB ENSG00000107338 SH2 domain containing adaptor protein B 9 37919134-38069211 Predicted intracellular proteins Evidence at protein level CAB010161, HPA049911, HPA052108 Uncertain Enhanced Nucleoplasm
Cytosol
Cytoplasmic bodies Expressed in all Expressed in all parathyroid gland: 16.2 Mixed +UBE2R2 CDC34B, FLJ20419, MGC10481, UBC3B ENSG00000107341 Ubiquitin conjugating enzyme E2 R2 9 33817567-33920404 Enzymes, Predicted intracellular proteins Evidence at protein level HPA061000 Approved Nucleus
Nucleoli Liver cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all testis: 68.7 Expressed in all +ABHD17B C9orf77, CGI-67, FAM108B1 ENSG00000107362 Abhydrolase domain containing 17B 9 71862452-71910931 Predicted intracellular proteins Evidence at protein level HPA047862 Uncertain Renal cancer:2.59e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 35.3 Mixed +EXOSC3 CGI-102, hRrp-40, hRrp40p, p10, RRP40, Rrp40p ENSG00000107371 Exosome component 3 9 37766978-37801437 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020485 Enhanced Supported Nucleoplasm Liver cancer:7.01e-5 (unfavourable), Melanoma:7.39e-4 (unfavourable) Expressed in all Mixed testis: 28.2 Expressed in all +ZFAND5 ZA20D2, ZFAND5A, ZNF216 ENSG00000107372 Zinc finger AN1-type containing 5 9 72351425-72365235 Predicted intracellular proteins Evidence at protein level HPA018129 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:4.43e-4 (favourable) Expressed in all Expressed in all adipose tissue: 310.8 Expressed in all +DVL1 ENSG00000107404 Dishevelled segment polarity protein 1 1 1335276-1349350 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011538 Approved Testis cancer:3.33e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 79.4 Expressed in all +PDLIM1 CLIM1, CLP-36, CLP36, hCLIM1 ENSG00000107438 PDZ and LIM domain 1 10 95237572-95291024 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017010, CAB072838, CAB072840 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Endometrial cancer:1.14e-5 (favourable) Expressed in all Expressed in all small intestine: 273.0 Cell line enhanced HaCaT: 680.7 +CCNJ bA690P14.1, FLJ10895 ENSG00000107443 Cyclin J 10 96043394-96060870 Predicted intracellular proteins Evidence at transcript level HPA036531, HPA058151 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 9.9 Mixed +DNTT TDT ENSG00000107447 DNA nucleotidylexotransferase 10 96304396-96338564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044194 Approved Nucleoplasm
Cytosol Not detected Tissue enriched 8 bone marrow: 18.3 tonsil: 2.1 Group enriched 518 MOLT-4: 325.2;REH: 1262.7 +GATA3 HDR ENSG00000107485 GATA binding protein 3 10 8053604-8075198 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB016217, HPA029730 Enhanced Supported Nucleoplasm Renal cancer:3.13e-4 (unfavourable) Group enriched Tissue enhanced parathyroid gland: 235.0;skin: 148.9 placenta: 44.3 Cell line enhanced BEWO: 172.2;MCF7: 354.3;RT4: 149.5;SH-SY5Y: 145.4;T-47d: 506.9 +ATRNL1 ALP, FLJ45344, KIAA0534 ENSG00000107518 Attractin like 1 10 115093365-115948992 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038070 Uncertain Approved Nucleus
Mitochondria Mixed Tissue enhanced cerebral cortex: 33.9 testis: 22.7 Cell line enhanced AN3-CA: 27.6;RH-30: 19.2 +HPS1 BLOC3S1, HPS ENSG00000107521 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 10 98416198-98446947 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA061260 Approved Endometrial cancer:2.93e-5 (favourable), Cervical cancer:3.37e-5 (favourable), Lung cancer:1.26e-4 (favourable), Glioma:5.53e-4 (unfavourable) Expressed in all Expressed in all lymph node: 24.2 Mixed +PHYH PAHX, PHYH1, RD ENSG00000107537 Phytanoyl-CoA 2-hydroxylase 10 13277796-13302412 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007598, HPA011796 Enhanced Renal cancer:7.28e-12 (favourable) Expressed in all Expressed in all liver: 334.1 Mixed +RASSF4 AD037, MGC44914 ENSG00000107551 Ras association domain family member 4 10 44959407-44995891 Predicted intracellular proteins Evidence at protein level HPA038834 Approved Approved Nucleus
Nucleoli
Cell Junctions Expressed in all Expressed in all cerebral cortex: 71.4 Cell line enhanced RH-30: 158.1;U-937: 67.6;WM-115: 54.3 +DNMBP ARHGEF36, KIAA1010, Tuba ENSG00000107554 Dynamin binding protein 10 99875577-100009919 Predicted intracellular proteins Evidence at protein level HPA037878, HPA058216 Uncertain Approved Nucleoli
Nuclear bodies
Golgi apparatus
Cytosol Endometrial cancer:4.95e-6 (favourable), Urothelial cancer:6.15e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.6 Mixed +RAB11FIP2 KIAA0941, nRip11, Rab11-FIP2 ENSG00000107560 RAB11 family interacting protein 2 10 118004916-118046603 Predicted intracellular proteins Evidence at protein level HPA037726 Approved Supported Nucleoplasm
Vesicles Renal cancer:9.69e-5 (favourable) Expressed in all Expressed in all seminal vesicle: 36.4 Expressed in all +CXCL12 PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1 ENSG00000107562 C-X-C motif chemokine ligand 12 10 44370165-44386493 Predicted secreted proteins Evidence at protein level CAB017564 Approved Expressed in all Expressed in all endometrium: 618.3 Cell line enhanced ASC diff: 349.6;BJ hTERT+ SV40 Large T+ RasG12V: 429.9;fHDF/TERT166: 388.7;HSkMC: 941.2 +ERLIN1 C10orf69, Erlin-1, KE04, SPFH1, SPG62 ENSG00000107566 ER lipid raft associated 1 10 100150094-100188334 Disease related genes, Predicted secreted proteins Evidence at protein level HPA011252 Approved Supported Endoplasmic reticulum Lung cancer:7.63e-4 (unfavourable) Expressed in all Expressed in all placenta: 57.2 Expressed in all +EIF3A EIF3, eIF3-p170, eIF3-theta, eIF3a, EIF3S10, KIAA0139, TIF32 ENSG00000107581 Eukaryotic translation initiation factor 3 subunit A 10 119033670-119080823 Predicted intracellular proteins Evidence at protein level HPA038315, HPA038316 Enhanced Supported Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland: 135.7 Expressed in all +PKD2L1 PCL, PKD2L, PKDL, TRPP3 ENSG00000107593 Polycystin 2 like 1, transient receptor potential cation channel 10 100288154-100330486 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB022621 Uncertain Mixed Tissue enhanced spleen: 9.8 lung: 3.4 Not detected +CUBN gp280, IFCR, MGA1 ENSG00000107611 Cubilin 10 16823964-17129831 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004133, HPA043854 Enhanced Renal cancer:1.12e-4 (favourable) Tissue enriched Group enriched 22 kidney: 153.7;small intestine: 54.4 thyroid gland: 4.7 Cell line enhanced AN3-CA: 14.6;WM-115: 5.9 +TRDMT1 DNMT2, RNMT1 ENSG00000107614 TRNA aspartic acid methyltransferase 1 10 17142254-17202054 Enzymes, Predicted intracellular proteins Evidence at protein level CAB009468, HPA036945, HPA036946 Approved Approved Nucleus
Nucleoli
Centrosome Mixed Mixed parathyroid gland: 8.7 Mixed +DDX50 GU2, GUB, MGC3199, RH-II/GuB ENSG00000107625 DExD-box helicase 50 10 68901278-68946847 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037388, HPA037389, HPA058196 Approved Enhanced Nucleoli Expressed in all Expressed in all testis: 47.0 Expressed in all +MAPK8 JNK, JNK1, PRKM8, SAPK1 ENSG00000107643 Mitogen-activated protein kinase 8 10 48306639-48439360 Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004463, CAB069396 Approved Liver cancer:8.66e-4 (unfavourable), Renal cancer:8.66e-4 (favourable) Expressed in all Expressed in all testis: 35.1 Expressed in all +SEC23IP p125 ENSG00000107651 SEC23 interacting protein 10 119892711-119944658 Predicted intracellular proteins Evidence at protein level HPA038403, HPA043305 Approved Enhanced Vesicles Expressed in all Expressed in all smooth muscle: 30.5 Expressed in all +ATE1 ENSG00000107669 Arginyltransferase 1 10 121740421-121928801 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038444, HPA057549 Approved Supported Nucleus Renal cancer:2.67e-4 (favourable) Expressed in all Expressed in all thyroid gland: 31.5 Expressed in all +NSMCE4A bA500G22.3, C10orf86, FLJ20003, NSE4A ENSG00000107672 NSE4 homolog A, SMC5-SMC6 complex component 10 121957088-121975217 Predicted intracellular proteins Evidence at protein level HPA037459, HPA038412, HPA044872 Approved Enhanced Nucleoplasm Lung cancer:2.72e-5 (favourable), Renal cancer:2.45e-4 (unfavourable) Expressed in all Expressed in all prostate: 34.5 Expressed in all +PLEKHA1 TAPP1 ENSG00000107679 Pleckstrin homology domain containing A1 10 122374696-122442602 Predicted intracellular proteins Evidence at protein level HPA002043, HPA064795 Approved Enhanced Nucleus
Cytosol Expressed in all Expressed in all skin: 79.2 Cell line enhanced RPTEC TERT1: 153.9 +PALD1 KIAA1274, PALD ENSG00000107719 Phosphatase domain containing, paladin 1 10 70478821-70568449 Predicted membrane proteins Evidence at protein level HPA015696, HPA017343 Uncertain Expressed in all Mixed lung: 15.0 Cell line enhanced AN3-CA: 20.7;Daudi: 19.8;RPMI-8226: 23.0 +UNC5B p53RDL1, UNC5H2 ENSG00000107731 Unc-5 netrin receptor B 10 71212570-71302864 Plasma proteins, Predicted membrane proteins Evidence at protein level Liver cancer:3.01e-5 (unfavourable), Ovarian cancer:3.80e-5 (unfavourable), Renal cancer:1.54e-4 (unfavourable) Expressed in all Tissue enhanced seminal vesicle: 38.5 cerebral cortex: 16.9 Cell line enhanced HHSteC: 122.9;hTCEpi: 95.5;SH-SY5Y: 131.0 +CDH23 CDHR23, DFNB12, USH1D ENSG00000107736 Cadherin related 23 10 71396934-71815947 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017232 Approved Urothelial cancer:3.40e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 30.2 ovary: 19.4 Cell line enhanced RT4: 11.9;SCLC-21H: 6.6 +VSIR B7-H5, B7H5, C10orf54, GI24, PD-1H, SISP1, VISTA ENSG00000107738 V-set immunoregulatory receptor 10 71747559-71773498 Predicted membrane proteins Evidence at protein level HPA007968 Approved Nucleoplasm Testis cancer:6.93e-4 (unfavourable) Expressed in all Expressed in all spleen: 184.9 Cell line enhanced CAPAN-2: 162.4;HaCaT: 105.4;HMC-1: 173.0;U-937: 130.3 +SPOCK2 KIAA0275, testican-2 ENSG00000107742 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 10 72059035-72089032 Predicted secreted proteins Evidence at protein level HPA044605 Supported Uncertain Nuclear speckles Head and neck cancer:1.95e-5 (favourable), Breast cancer:4.05e-4 (favourable), Melanoma:4.72e-4 (favourable), Ovarian cancer:7.19e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 161.8;lung: 127.8 lymph node: 75.1 Group enriched 8 Hep G2: 33.9;SCLC-21H: 79.9 +MICU1 CALC, CBARA1, EFHA3, FLJ12684 ENSG00000107745 Mitochondrial calcium uptake 1 10 72367327-72626191 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA037479, HPA037480 Uncertain Supported Mitochondria Renal cancer:4.66e-7 (favourable) Expressed in all Expressed in all kidney: 107.8 Expressed in all +PPP3CB CALNA2, CALNB, CNA2, PP2Bbeta ENSG00000107758 Protein phosphatase 3 catalytic subunit beta 10 73436428-73496024 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008233, HPA008823 Uncertain Approved Mitochondria Pancreatic cancer:6.96e-5 (favourable), Liver cancer:9.59e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 153.2 Expressed in all +CCSER2 FAM190B, KIAA1128 ENSG00000107771 Coiled-coil serine rich protein 2 10 84328586-84518521 Predicted intracellular proteins Evidence at protein level HPA037481, HPA037482 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 39.5 Expressed in all +BMPR1A ACVRLK3, ALK3, CD292 ENSG00000107779 Bone morphogenetic protein receptor type 1A 10 86756601-86932838 Cancer-related genes, CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB019398 Approved Approved Cytosol Liver cancer:8.93e-4 (unfavourable), Glioma:9.38e-4 (favourable) Expressed in all Mixed thyroid gland: 19.6 Mixed +MINPP1 MIPP ENSG00000107789 Multiple inositol-polyphosphate phosphatase 1 10 87504875-87553460 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026859 Approved Renal cancer:6.98e-5 (unfavourable) Expressed in all Expressed in all placenta: 27.6 Mixed +ACTA2 ACTSA ENSG00000107796 Actin, alpha 2, smooth muscle, aorta 10 88935074-88991339 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000002, CAB003761, CAB013531, HPA041264, HPA041271 Enhanced Supported Actin filaments Renal cancer:1.37e-8 (unfavourable) Expressed in all Expressed in all smooth muscle: 11741.0 Cell line enhanced ASC TERT1: 273.9;fHDF/TERT166: 496.7;HHSteC: 525.6;HSkMC: 250.7 +LIPA CESD, LAL ENSG00000107798 Lipase A, lysosomal acid type 10 89213569-89414557 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB034892, HPA057052 Enhanced Supported Vesicles Expressed in all Expressed in all spleen: 496.6 Mixed +TLX1 HOX11, TCL3 ENSG00000107807 T-cell leukemia homeobox 1 10 101130505-101137789 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Colorectal cancer:7.32e-4 (unfavourable) Mixed Tissue enriched 5 spleen: 31.3 salivary gland: 6.0 Cell line enhanced HAP1: 4.1;K-562: 10.7;SH-SY5Y: 2.9 +TWNK C10orf2, FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL ENSG00000107815 Twinkle mtDNA helicase 10 100987367-100994401 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002532 Uncertain Expressed in all Expressed in all testis: 13.6 Expressed in all +LZTS2 KIAA1813, LAPSER1 ENSG00000107816 Leucine zipper tumor suppressor 2 10 100996618-101007836 Predicted intracellular proteins Evidence at protein level HPA044956 Approved Approved Plasma membrane
Cytosol Renal cancer:3.39e-4 (unfavourable), Colorectal cancer:8.23e-4 (unfavourable) Expressed in all Expressed in all endometrium,seminal vesicle: 57.9 Expressed in all +SFXN3 SFX3 ENSG00000107819 Sideroflexin 3 10 101031234-101041244 Predicted membrane proteins Evidence at protein level HPA008028, HPA048105 Approved Enhanced Mitochondria Head and neck cancer:3.79e-4 (unfavourable), Renal cancer:4.94e-4 (unfavourable) Expressed in all Expressed in all small intestine: 41.4 Mixed +KAZALD1 FKSG28, FKSG40 ENSG00000107821 Kazal type serine peptidase inhibitor domain 1 10 101061841-101068131 Predicted secreted proteins Evidence at protein level HPA011800 Uncertain Thyroid cancer:5.10e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 26.8 cervix, uterine: 15.7 Cell line enhanced AN3-CA: 35.1;T-47d: 45.4 +FBXW4 dactylin, Fbw4, SHFM3 ENSG00000107829 F-box and WD repeat domain containing 4 10 101610664-101695295 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043496 Approved Approved Golgi apparatus Renal cancer:3.41e-5 (favourable), Pancreatic cancer:4.67e-4 (favourable), Endometrial cancer:4.91e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 80.8 Expressed in all +FGF8 AIGF ENSG00000107831 Fibroblast growth factor 8 10 101770130-101780369 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Group enriched Tissue enriched 7 skeletal muscle: 15.7 testis: 2.2 Cell line enriched 29 RH-30: 40.4 +NPM3 ENSG00000107833 Nucleophosmin/nucleoplasmin 3 10 101781325-101783413 Predicted intracellular proteins Evidence at protein level HPA036295, HPA036296 Approved Approved Nucleoli
Actin filaments
Cytosol Head and neck cancer:1.42e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 28.8 Expressed in all +TNKS2 PARP-5b, PARP-5c, PARP5B, PARP5C, pART6, TANK2, TNKL ENSG00000107854 Tankyrase 2 10 91798312-91865276 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036606 Approved Microtubules Expressed in all Expressed in all thyroid gland: 50.4 Expressed in all +PITX3 ASMD ENSG00000107859 Paired like homeodomain 3 10 102230186-102241474 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Group enriched 11 adipose tissue: 1.2;skeletal muscle: 5.6 testis: 0.3 Cell line enriched 17 RH-30: 28.7 +GBF1 ARF1GEF, KIAA0248 ENSG00000107862 Golgi brefeldin A resistant guanine nucleotide exchange factor 1 10 102245532-102382899 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037759, HPA037760 Uncertain Supported Golgi apparatus Expressed in all Expressed in all parathyroid gland: 59.2 Expressed in all +ARHGAP21 ARHGAP10, KIAA1424 ENSG00000107863 Rho GTPase activating protein 21 10 24583609-24723668 Predicted intracellular proteins Evidence at protein level HPA036610, HPA057861 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Expressed in all Expressed in all cerebral cortex: 88.5 Mixed +CPEB3 KIAA0940 ENSG00000107864 Cytoplasmic polyadenylation element binding protein 3 10 92046692-92291087 Predicted intracellular proteins Evidence at protein level HPA059056 Approved Nucleoplasm
Nuclear bodies
Intermediate filaments Renal cancer:3.84e-9 (favourable), Liver cancer:5.06e-5 (favourable) Mixed Mixed testis: 16.2 Cell line enhanced Karpas-707: 8.9 +FBXL15 Fbl15, FBXO37, MGC11279 ENSG00000107872 F-box and leucine rich repeat protein 15 10 102419189-102423136 Predicted intracellular proteins Evidence at protein level Renal cancer:7.82e-4 (favourable), Urothelial cancer:7.92e-4 (favourable) Expressed in all Mixed cerebral cortex: 13.4 Mixed +CUEDC2 C10orf66, MGC2491 ENSG00000107874 CUE domain containing 2 10 102423245-102432661 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036544, HPA041829 Uncertain Enhanced Nucleoplasm
Cytosol Liver cancer:2.75e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 89.9 Expressed in all +SUFU PRO1280, SUFUH, SUFUXL ENSG00000107882 SUFU negative regulator of hedgehog signaling 10 102503987-102633535 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008700 Enhanced Supported Nucleus Expressed in all Mixed parathyroid gland: 16.1 Expressed in all +ANKRD26 KIAA1074, THC2 ENSG00000107890 Ankyrin repeat domain 26 10 26991914-27100498 Predicted intracellular proteins Evidence at protein level HPA040654, HPA041460 Approved Approved Golgi apparatus
Vesicles Expressed in all Mixed testis: 10.7 Expressed in all +ACBD5 DKFZp434A2417, KIAA1996 ENSG00000107897 Acyl-CoA binding domain containing 5 10 27195214-27242130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011861, HPA012145 Enhanced Enhanced Peroxisomes Renal cancer:4.68e-5 (favourable), Breast cancer:3.33e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 57.1 Expressed in all +LHPP HDHD2B ENSG00000107902 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase 10 124461834-124617888 Enzymes, Predicted intracellular proteins Evidence at protein level HPA009163, HPA009269 Enhanced Supported Nuclear speckles
Cytosol Expressed in all Expressed in all cerebral cortex: 70.6 Mixed +LARP4B KIAA0217, LARP5 ENSG00000107929 La ribonucleoprotein domain family member 4B 10 806914-931705 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036566, HPA042738 Approved Enhanced Cytosol Liver cancer:1.70e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 38.1 Expressed in all +GTPBP4 CRFG, FLJ10686, FLJ10690, NGB, NOG1 ENSG00000107937 GTP binding protein 4 10 988019-1019936 Predicted intracellular proteins Evidence at protein level HPA039618, HPA056468 Uncertain Enhanced Nuclear membrane
Nucleoli Liver cancer:8.85e-12 (unfavourable), Renal cancer:2.38e-5 (unfavourable), Endometrial cancer:4.57e-4 (unfavourable) Expressed in all Expressed in all testis: 37.3 Expressed in all +EDRF1 C10orf137, DKFZp586F1019, FLJ21617 ENSG00000107938 Erythroid differentiation regulatory factor 1 10 125719515-125764143 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031820 Approved Nucleoplasm
Centrosome
Cytosol Renal cancer:3.16e-5 (unfavourable) Expressed in all Expressed in all testis: 28.2 Expressed in all +BCCIP BCCIPalpha, TOK-1 ENSG00000107949 BRCA2 and CDKN1A interacting protein 10 125823546-125853695 Predicted intracellular proteins Evidence at protein level HPA038011 Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 89.5 Expressed in all +MTPAP FLJ10486, mtPAP, PAPD1, SPAX4 ENSG00000107951 Mitochondrial poly(A) polymerase 10 30309801-30374448 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038620, HPA058232 Approved Supported Mitochondria Liver cancer:4.20e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 22.7 Expressed in all +NEURL1 h-neu, neu-1, NEURL, RNF67 ENSG00000107954 Neuralized E3 ubiquitin protein ligase 1 10 103493979-103592552 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA044204 Uncertain Mixed Tissue enhanced skeletal muscle: 50.9 cerebral cortex: 30.1 Cell line enhanced BEWO: 13.2;SCLC-21H: 20.2;SiHa: 9.4 +SH3PXD2A FISH, KIAA0418, SH3MD1 ENSG00000107957 SH3 and PX domains 2A 10 103594027-103855543 Predicted intracellular proteins Evidence at protein level HPA037922, HPA037923 Approved Renal cancer:2.04e-6 (unfavourable), Ovarian cancer:3.18e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 63.3 Cell line enhanced BJ hTERT+: 68.9 +PITRM1 hMP1, KIAA1104, MP1, PreP ENSG00000107959 Pitrilysin metallopeptidase 1 10 3137728-3172841 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006753, HPA006754 Enhanced Supported Mitochondria Expressed in all Expressed in all testis: 86.6 Expressed in all +STN1 bA541N10.2, FLJ22559, OBFC1 ENSG00000107960 STN1, CST complex subunit 10 103882542-103918205 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037924, HPA037925 Supported Nucleus Renal cancer:1.12e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 49.8 Expressed in all +MAP3K8 c-COT, COT, EST, ESTF, MEKK8, Tpl-2 ENSG00000107968 Mitogen-activated protein kinase kinase kinase 8 10 30433937-30461833 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005120, HPA017962 Supported Supported Cytosol Renal cancer:8.76e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 209.6 Mixed +DKK1 DKK-1, SK ENSG00000107984 Dickkopf WNT signaling pathway inhibitor 1 10 52314296-52318042 Predicted secreted proteins Evidence at protein level Head and neck cancer:4.35e-8 (unfavourable), Lung cancer:7.80e-6 (unfavourable), Pancreatic cancer:1.27e-4 (unfavourable) Mixed Tissue enhanced cervix, uterine: 56.5;placenta: 71.9 urinary bladder: 14.5 Cell line enhanced BJ: 975.2;CACO-2: 841.6;fHDF/TERT166: 1247.0 +EBF3 COE3, DKFZp667B0210 ENSG00000108001 Early B-cell factor 3 10 129835283-129963841 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA061169 Approved Nucleoplasm
Vesicles Mixed Tissue enhanced adipose tissue: 20.1 lymph node: 12.7 Cell line enhanced HAP1: 23.0;LHCN-M2: 29.6;NB-4: 29.2;RH-30: 18.6;SCLC-21H: 53.2 +GLRX3 bA500G10.4, GLRX4, GRX3, GRX4, PICOT, TXNL2 ENSG00000108010 Glutaredoxin 3 10 130136399-130184521 Predicted intracellular proteins Evidence at protein level HPA028941 Approved Liver cancer:9.03e-6 (unfavourable), Renal cancer:9.24e-6 (unfavourable) Expressed in all Expressed in all testis: 119.3 Expressed in all +SORCS1 sorCS1 ENSG00000108018 Sortilin related VPS10 domain containing receptor 1 10 106573663-107164534 Predicted membrane proteins Evidence at protein level HPA011948 Approved Approved Plasma membrane
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 12.2;thyroid gland: 18.1 kidney: 4.8 Group enriched 12 RH-30: 78.2;SH-SY5Y: 111.4 +FAM208B bA318E3.2, C10orf18, FLJ20360, KIAA2006 ENSG00000108021 Family with sequence similarity 208 member B 10 5684838-5763740 Predicted intracellular proteins Evidence at protein level HPA038042, HPA038043, HPA061547 Uncertain Supported Nucleus
Cytosol Liver cancer:2.91e-4 (unfavourable) Expressed in all Expressed in all testis: 44.0 Expressed in all +XPNPEP1 XPNPEP, XPNPEPL, XPNPEPL1 ENSG00000108039 X-prolyl aminopeptidase 1 10 109864766-109923553 Enzymes, Predicted intracellular proteins Evidence at protein level CAB025196, HPA030419, HPA030420, HPA030422 Supported Enhanced Cytosol Liver cancer:2.12e-5 (unfavourable) Expressed in all Expressed in all small intestine: 66.1 Expressed in all +SMC3 BAM, bamacan, CSPG6, HCAP, SMC3L1 ENSG00000108055 Structural maintenance of chromosomes 3 10 110567691-110604636 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037411, HPA043206 Uncertain Supported Nucleoplasm Expressed in all Expressed in all testis: 94.9 Expressed in all +SHOC2 KIAA0862, SOC-2, SOC2, SUR-8, SUR8 ENSG00000108061 SHOC2, leucine rich repeat scaffold protein 10 110919547-111013667 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA009164 Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 65.3 Expressed in all +TFAM TCF6, TCF6L2 ENSG00000108064 Transcription factor A, mitochondrial 10 58385022-58399221 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA040648, HPA063684 Supported Enhanced Mitochondria Renal cancer:2.22e-5 (favourable), Ovarian cancer:2.74e-4 (favourable), Endometrial cancer:8.73e-4 (unfavourable) Expressed in all Expressed in all testis: 62.3 Expressed in all +CCDC6 D10S170, H4, PTC, TPC, TST1 ENSG00000108091 Coiled-coil domain containing 6 10 59788763-59906656 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019049, HPA019051 Enhanced Supported Cytosol Liver cancer:1.11e-4 (unfavourable), Pancreatic cancer:3.95e-4 (unfavourable), Head and neck cancer:5.48e-4 (favourable) Expressed in all Expressed in all smooth muscle: 44.4 Expressed in all +CUL2 ENSG00000108094 Cullin 2 10 35008551-35090642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB002677, HPA024578 Approved Enhanced Nucleoplasm Liver cancer:8.24e-6 (unfavourable), Renal cancer:9.32e-5 (unfavourable) Expressed in all Expressed in all testis: 65.1 Expressed in all +CCNY C10orf9, CBCP1, CFP1 ENSG00000108100 Cyclin Y 10 35247025-35572669 Predicted intracellular proteins Evidence at protein level HPA036290 Approved Liver cancer:6.75e-5 (unfavourable) Expressed in all Expressed in all testis: 149.9 Expressed in all +UBE2S E2-EPF ENSG00000108106 Ubiquitin conjugating enzyme E2 S 19 55399745-55407777 Enzymes, Predicted intracellular proteins Evidence at protein level CAB015228, HPA057150 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:8.16e-8 (unfavourable), Liver cancer:8.00e-6 (unfavourable), Endometrial cancer:2.05e-4 (unfavourable) Expressed in all Expressed in all testis: 120.1 Expressed in all +RPL28 FLJ43307, L28 ENSG00000108107 Ribosomal protein L28 19 55385345-55403250 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050459 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:6.61e-5 (unfavourable) Expressed in all Expressed in all lymph node: 1969.2 Expressed in all +ZMIZ1 FLJ13541, hZIMP10, KIAA1224, MIZ, RAI17, RP11-519K18.1, Zimp10 ENSG00000108175 Zinc finger MIZ-type containing 1 10 79069035-79316528 Predicted intracellular proteins Evidence at protein level HPA045144 Approved Approved Nucleoplasm
Vesicles Renal cancer:3.64e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 65.3 Mixed +DNAJC12 JDP1 ENSG00000108176 DnaJ heat shock protein family (Hsp40) member C12 10 67796665-67838166 Predicted intracellular proteins Evidence at protein level HPA036289 Enhanced Renal cancer:1.97e-10 (unfavourable) Tissue enhanced Tissue enhanced adrenal gland: 57.7 breast: 39.4 Cell line enhanced Daudi: 66.4;SCLC-21H: 86.3 +PPIF Cyp-D, hCyP3 ENSG00000108179 Peptidylprolyl isomerase F 10 79347469-79355337 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA077416 Supported Mitochondria Expressed in all Expressed in all adrenal gland: 188.4 Expressed in all +PBLD FLJ14767, MAWBP, MAWDBP ENSG00000108187 Phenazine biosynthesis like protein domain containing 10 68282660-68333049 Predicted intracellular proteins Evidence at protein level HPA038035, HPA038036 Enhanced Approved Vesicles Liver cancer:1.44e-4 (favourable) Expressed in all Expressed in all kidney: 278.7 Expressed in all +TSPAN14 DC-TM4F2, MGC11352, TM4SF14 ENSG00000108219 Tetraspanin 14 10 80454166-80533123 Predicted membrane proteins, Transporters Evidence at protein level HPA014773, HPA057174 Uncertain Supported Vesicles Cervical cancer:3.56e-4 (favourable), Renal cancer:4.20e-4 (favourable) Expressed in all Expressed in all placenta: 129.4 Mixed +LGI1 EPITEMPIN, EPT, ETL1, IB1099 ENSG00000108231 Leucine rich glioma inactivated 1 10 93757809-93806272 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Group enriched Tissue enriched 11 cerebral cortex: 45.4 esophagus: 4.2 Group enriched 5 AF22: 9.4;NTERA-2: 6.4 +TBC1D12 KIAA0608 ENSG00000108239 TBC1 domain family member 12 10 94402504-94535930 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA038277, HPA038645 Uncertain Approved Nucleoplasm
Nuclear speckles Colorectal cancer:1.79e-5 (favourable) Expressed in all Mixed parathyroid gland: 19.4 Mixed +CYP2C18 CPCI, CYP2C, CYP2C17, P450IIC17 ENSG00000108242 Cytochrome P450 family 2 subfamily C member 18 10 94683621-94736190 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Group enriched 11 duodenum: 103.1;esophagus: 24.6;gallbladder: 24.5;liver: 97.8;small intestine: 88.1;stomach: 62.2 tonsil: 6.2 Cell line enhanced BEWO: 3.0 +KRT23 CK23, DKFZP434G032, HAIK1, K23, MGC26158 ENSG00000108244 Keratin 23 17 40922696-40937634 Predicted intracellular proteins Evidence at protein level HPA012050, HPA016959, CAB017091 Approved Approved Intermediate filaments
Cytosol Urothelial cancer:8.26e-4 (unfavourable) Mixed Tissue enhanced placenta: 68.6;skin: 70.9 salivary gland: 41.2 Group enriched 8 HBEC3-KT: 28.8;Hep G2: 17.3;T-47d: 63.7 +CRYBA1 CRYB1 ENSG00000108255 Crystallin beta A1 17 29246863-29254494 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022016 Supported Not detected Not detected appendix: 0.2 Group enriched 8 AF22: 3.2;BEWO: 4.1 +NUFIP2 182-FIP, 82-FIP, FIP-82, KIAA1321, MGC117262, PIG1 ENSG00000108256 NUFIP2, FMR1 interacting protein 2 17 29255836-29294118 Predicted intracellular proteins Evidence at protein level HPA067443 Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all bone marrow: 53.3 Expressed in all +GIT1 ENSG00000108262 GIT ArfGAP 1 17 29573469-29594054 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004059, HPA004186 Approved Enhanced Focal adhesion sites
Cytosol Liver cancer:2.54e-6 (unfavourable) Expressed in all Expressed in all testis: 127.3 Expressed in all +RPL19 DKFZp779D216, FLJ27452, L19, MGC71997 ENSG00000108298 Ribosomal protein L19 17 39200283-39204727 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043014, HPA051987 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:6.87e-5 (unfavourable) Expressed in all Expressed in all ovary: 4350.4 Cell line enriched 6 SK-BR-3: 28538.8 +FBXL20 Fbl2, Fbl20, MGC15482 ENSG00000108306 F-box and leucine rich repeat protein 20 17 39252644-39402523 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044748, HPA050397 Uncertain Supported Microtubules Ovarian cancer:9.54e-4 (unfavourable) Expressed in all Mixed testis: 23.0 Expressed in all +RUNDC3A RAP2IP, RPIP8 ENSG00000108309 RUN domain containing 3A 17 44308413-44318671 Predicted intracellular proteins Evidence at protein level HPA023548, HPA070733 Enhanced Supported Approved Vesicles Tissue enhanced Tissue enriched 10 cerebral cortex: 178.0 adrenal gland: 18.2 Group enriched 8 SCLC-21H: 72.5;SH-SY5Y: 41.7 +UBTF NOR-90, UBF, UBF1, UBF2 ENSG00000108312 Upstream binding transcription factor, RNA polymerase I 17 44205033-44221626 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004611, HPA006385 Enhanced Supported Enhanced Nucleoli fibrillar center Expressed in all Expressed in all parathyroid gland: 81.5 Expressed in all +CSF3 C17orf33, G-CSF, GCSF, MGC45931 ENSG00000108342 Colony stimulating factor 3 17 40015361-40017813 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Endometrial cancer:8.45e-4 (favourable) Mixed Tissue enhanced appendix: 19.1;cervix, uterine: 38.2 adipose tissue: 10.3 Cell line enhanced BJ hTERT+: 57.2;hTEC/SVTERT24-B: 34.2;U-87 MG: 265.0 +PSMD3 P58, Rpn3, S3, TSTA2 ENSG00000108344 Proteasome 26S subunit, non-ATPase 3 17 39980797-39997960 Predicted intracellular proteins Evidence at protein level CAB017038, HPA048972 Approved Supported Nucleoplasm
Cytosol Renal cancer:4.47e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 83.6 Expressed in all +CASC3 BTZ, MLN51 ENSG00000108349 Cancer susceptibility 3 17 40140318-40172183 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level HPA024592, HPA050262 Approved Approved Nuclear membrane Expressed in all Expressed in all testis: 95.2 Expressed in all +RAPGEFL1 Link-GEFII ENSG00000108352 Rap guanine nucleotide exchange factor like 1 17 40177010-40195656 Predicted intracellular proteins Evidence at protein level HPA022895 Approved Nucleus
Microtubules
Cytokinetic bridge Renal cancer:0.00e+0 (unfavourable), Cervical cancer:3.28e-4 (favourable), Breast cancer:8.43e-4 (favourable) Expressed in all Tissue enhanced skin: 277.1 esophagus: 93.2 Expressed in all +RGS9 MGC111763, MGC26458, PERRS, RGS9L ENSG00000108370 Regulator of G-protein signaling 9 17 65100812-65227703 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013550, HPA014137 Supported Supported Uncertain Nucleoplasm Pancreatic cancer:1.35e-4 (favourable) Mixed Mixed fallopian tube: 5.5 Group enriched 9 HDLM-2: 24.5;HEL: 9.6 +RNF43 DKFZp781H0392, FLJ20315, URCC ENSG00000108375 Ring finger protein 43 17 58352500-58417595 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA008079 Uncertain Renal cancer:6.04e-9 (favourable) Tissue enhanced Mixed duodenum: 23.4 Cell line enhanced CACO-2: 20.6;Hep G2: 33.5 +WNT3 INT4, MGC131950, MGC138321, MGC138323 ENSG00000108379 Wnt family member 3 17 46762506-46833154 Disease related genes, Predicted secreted proteins Evidence at protein level Tissue enriched Group enriched 6 duodenum: 2.2;parathyroid gland: 4.3;skin: 9.3 cerebral cortex: 0.9 Cell line enhanced AF22: 6.9;U-698: 5.4 +ASPA ACY2, ASP ENSG00000108381 Aspartoacylase 17 3472374-3503419 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA022142, HPA022145 Enhanced Uncertain Cytosol Tissue enhanced Tissue enhanced kidney: 39.8 cerebral cortex: 24.7 Cell line enhanced ASC diff: 3.7;HSkMC: 5.5 +RAD51C FANCO, RAD51L2 ENSG00000108384 RAD51 paralog C 17 58692573-58735611 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045198 Supported Nucleus
Vesicles
Cell Junctions
Mitochondria
Cytosol Liver cancer:8.68e-5 (unfavourable), Pancreatic cancer:5.33e-4 (favourable) Expressed in all Expressed in all testis: 37.3 Expressed in all +SEPT4 ARTS, CE5B3, H5, hCDCREL-2, hucep-7, MART, PNUTL2 ENSG00000108387 Septin 4 17 58520250-58540818 Predicted intracellular proteins Evidence at protein level CAB006855, HPA021587, HPA022905 Enhanced Supported Nucleoplasm Renal cancer:3.28e-7 (unfavourable) Expressed in all Tissue enhanced adrenal gland: 217.2;cerebral cortex: 287.9 spleen: 56.8 Cell line enhanced HHSteC: 11.8;SK-MEL-30: 25.2 +MTMR4 KIAA0647, ZFYVE11 ENSG00000108389 Myotubularin related protein 4 17 58489529-58517905 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:1.53e-5 (unfavourable), Pancreatic cancer:5.09e-4 (favourable) Expressed in all Expressed in all testis: 35.2 Expressed in all +TRIM37 KIAA0898, MUL, POB1, TEF3 ENSG00000108395 Tripartite motif containing 37 17 58982638-59106921 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021911 Uncertain Liver cancer:4.99e-6 (unfavourable) Expressed in all Expressed in all testis: 117.5 Expressed in all +P2RX1 P2X1 ENSG00000108405 Purinergic receptor P2X 1 17 3896592-3916500 Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced seminal vesicle: 46.2;urinary bladder: 41.9 bone marrow: 26.3 Cell line enhanced HEL: 12.5;HMC-1: 7.5;Karpas-707: 12.1;THP-1: 9.6;U-937: 5.8 +DHX40 ARG147, DDX40, FLJ22060, PAD ENSG00000108406 DEAH-box helicase 40 17 59565525-59608345 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044350 Uncertain Supported Nucleus Colorectal cancer:4.05e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 89.6 Expressed in all +KRT37 KRTHA7 ENSG00000108417 Keratin 37 17 41420753-41424523 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced skin: 1.2 cervix, uterine: 0.3 Not detected +TUBD1 FLJ12709, TUBD ENSG00000108423 Tubulin delta 1 17 59859482-59892945 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB004609, HPA023980, HPA027090 Approved Enhanced Nucleoplasm
Cytosol Liver cancer:1.00e-5 (unfavourable), Colorectal cancer:2.04e-4 (favourable), Renal cancer:6.06e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 12.5 Expressed in all +KPNB1 IMB1, Impnb, IPO1, IPOB, MGC2155, MGC2156, MGC2157, NTF97 ENSG00000108424 Karyopherin subunit beta 1 17 47649476-47685505 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA029878, CAB034449, HPA050302 Enhanced Supported Nucleoplasm
Nuclear membrane
Cytosol Liver cancer:2.55e-7 (unfavourable), Renal cancer:8.43e-6 (unfavourable) Expressed in all Expressed in all testis: 219.3 Expressed in all +GOSR2 Bos1, GS27 ENSG00000108433 Golgi SNAP receptor complex member 2 17 46923075-46975524 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017456, HPA048956, HPA054472 Uncertain Supported Nucleoplasm
Golgi apparatus Liver cancer:3.80e-4 (unfavourable) Expressed in all Expressed in all testis: 63.6 Expressed in all +PNPO PDXPO ENSG00000108439 Pyridoxamine 5'-phosphate oxidase 17 47941506-47948288 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA023204, HPA027776 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Expressed in all liver: 51.3 Mixed +RPS6KB1 p70(S6K)-alpha, PS6K, S6K1, STK14A ENSG00000108443 Ribosomal protein S6 kinase B1 17 59893046-59950564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003838, CAB018346, HPA039442 Approved Supported Nucleoplasm Renal cancer:5.09e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.3 Expressed in all +TRIM16L TRIM70 ENSG00000108448 Tripartite motif containing 16-like 17 18697998-18736118 Predicted intracellular proteins Evidence at protein level HPA066431 Approved Plasma membrane
Cytosol Thyroid cancer:2.29e-5 (unfavourable), Liver cancer:2.87e-4 (unfavourable) Expressed in all Mixed gallbladder: 22.7 Cell line enhanced A549: 290.9;HeLa: 215.6 +CDK5RAP3 C53, FLJ13660, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114 ENSG00000108465 CDK5 regulatory subunit associated protein 3 17 47967810-47981774 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022141, HPA022882, HPA027883 Supported Supported Cytosol Renal cancer:3.61e-5 (unfavourable), Urothelial cancer:7.31e-5 (favourable) Expressed in all Expressed in all epididymis: 110.2 Expressed in all +CBX1 CBX, HP1-BETA, HP1Hs-beta, M31, MOD1 ENSG00000108468 Chromobox 1 17 48070052-48101521 Predicted intracellular proteins Evidence at protein level CAB012265 Supported Supported Nucleus
Nuclear bodies Liver cancer:2.70e-4 (unfavourable) Expressed in all Expressed in all testis: 125.3 Expressed in all +RECQL5 FLJ90603, RecQ5 ENSG00000108469 RecQ like helicase 5 17 75626845-75667189 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029971 Supported Nucleus
Cytosol Endometrial cancer:1.73e-6 (unfavourable), Pancreatic cancer:4.34e-4 (favourable) Expressed in all Expressed in all thyroid gland: 26.9 Expressed in all +PIGL ENSG00000108474 Phosphatidylinositol glycan anchor biosynthesis class L 17 16217191-16351797 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA012739 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.47e-4 (unfavourable), Prostate cancer:2.57e-4 (unfavourable) Expressed in all Expressed in all epididymis,thyroid gland: 14.7 Mixed +GALK1 GALK ENSG00000108479 Galactokinase 1 17 75751594-75765711 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007094, HPA016960 Approved Approved Golgi apparatus
Cytosol Renal cancer:1.55e-6 (unfavourable), Urothelial cancer:1.62e-5 (unfavourable) Expressed in all Expressed in all liver: 23.4 Expressed in all +INTS2 INT2, KIAA1287 ENSG00000108506 Integrator complex subunit 2 17 61865367-61928016 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049524 Uncertain Thyroid cancer:2.20e-4 (unfavourable), Liver cancer:4.37e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 11.5 Expressed in all +CAMTA2 KIAA0909 ENSG00000108509 Calmodulin binding transcription activator 2 17 4967992-4987652 Predicted intracellular proteins Evidence at protein level HPA051147 Approved Nucleus
Actin filaments
Mitochondria Pancreatic cancer:6.00e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 40.5 Mixed +MED13 KIAA0593, THRAP1, TRAP240 ENSG00000108510 Mediator complex subunit 13 17 61942605-62065282 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA067939 Supported Nucleus Colorectal cancer:1.43e-4 (favourable) Expressed in all Expressed in all parathyroid gland,testis: 35.7 Expressed in all +HOXB6 HOX2, HOX2B ENSG00000108511 Homeobox B6 17 48595751-48604992 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042063 Approved Nucleus
Golgi apparatus Endometrial cancer:2.46e-4 (favourable) Tissue enhanced Tissue enhanced epididymis: 48.7;seminal vesicle: 30.1 cervix, uterine: 26.4 Cell line enhanced HEK 293: 71.9;RPTEC TERT1: 39.9 +ENO3 ENSG00000108515 Enolase 3 17 4948092-4957131 Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000793, HPA068284, HPA068721 Enhanced Supported Plasma membrane
Cytosol Colorectal cancer:7.33e-4 (unfavourable) Expressed in all Tissue enriched 17 skeletal muscle: 5974.6 heart muscle: 350.1 Expressed in all +PFN1 ENSG00000108518 Profilin 1 17 4945652-4949061 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB037134, CAB037140 Enhanced Supported Cytosol Renal cancer:1.06e-4 (unfavourable) Expressed in all Expressed in all appendix: 890.4 Expressed in all +RNF167 DKFZP566H073 ENSG00000108523 Ring finger protein 167 17 4940008-4945222 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA049810 Approved Approved Cytosol Pancreatic cancer:2.03e-6 (favourable), Renal cancer:4.47e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 116.9 Expressed in all +SLC25A11 OGC, SLC20A4 ENSG00000108528 Solute carrier family 25 member 11 17 4937130-4940251 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA021167 Approved Renal cancer:2.84e-9 (favourable), Pancreatic cancer:6.41e-6 (favourable) Expressed in all Expressed in all heart muscle: 152.4 Expressed in all +RASD1 AGS1, DEXRAS1 ENSG00000108551 Ras related dexamethasone induced 1 17 17494437-17496395 Predicted intracellular proteins Evidence at protein level HPA047896 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all adipose tissue: 113.2 Cell line enhanced ASC diff: 48.2;REH: 65.3 +CHRNE ACHRE ENSG00000108556 Cholinergic receptor nicotinic epsilon subunit 17 4897774-4903074 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Mixed Tissue enriched 26 heart muscle: 33.9 epididymis: 1.3 Group enriched 15 HEL: 3.9;HMC-1: 9.2 +RAI1 DKFZP434A139, KIAA1820, MGC12824, SMCR, SMS ENSG00000108557 Retinoic acid induced 1 17 17681473-17811453 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023898, HPA054906 Approved Enhanced Nucleoplasm Ovarian cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 19.7 Expressed in all +NUP88 MGC8530 ENSG00000108559 Nucleoporin 88 17 5360963-5420160 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB002209, HPA021816 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 94.6 Expressed in all +C1QBP gC1Q-R, gC1qR, HABP1, p32, SF2p32 ENSG00000108561 Complement C1q binding protein 17 5432777-5448830 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA026483 Supported Approved Plasma membrane
Mitochondria Expressed in all Expressed in all rectum: 157.0 Expressed in all +SLC6A4 5-HTT, HTT, OCD1, SERT1 ENSG00000108576 Solute carrier family 6 member 4 17 30194319-30236002 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA071354, HPA074728 Supported Supported Golgi apparatus
Vesicles Tissue enhanced Group enriched 10 duodenum: 10.4;lung: 44.2;placenta: 26.4;small intestine: 45.3 esophagus: 3.1 Cell line enhanced BEWO: 1.9;CACO-2: 3.2;Hep G2: 7.1 +BLMH BH ENSG00000108578 Bleomycin hydrolase 17 30248195-30292056 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039548, HPA064307 Enhanced Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all skin: 139.9 Mixed +CPD GP180 ENSG00000108582 Carboxypeptidase D 17 30378905-30469989 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052796, HPA055465 Approved Approved Nucleoplasm
Nuclear membrane
Nuclear speckles Expressed in all Expressed in all thyroid gland: 94.8 Expressed in all +GOSR1 GOLIM2, GOS-28, GOS28, GS28, P28 ENSG00000108587 Golgi SNAP receptor complex member 1 17 30477362-30527592 Predicted membrane proteins Evidence at protein level HPA020590 Uncertain Renal cancer:2.26e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 55.5 Expressed in all +CCDC47 GK001 ENSG00000108588 Coiled-coil domain containing 47 17 63745250-63776351 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029674, HPA072573 Approved Enhanced Endoplasmic reticulum Colorectal cancer:2.17e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 161.4 Expressed in all +MED31 CGI-125, Soh1 ENSG00000108590 Mediator complex subunit 31 17 6643315-6651634 Predicted intracellular proteins Evidence at protein level HPA035947 Uncertain Approved Nucleus Expressed in all Expressed in all epididymis: 32.2 Expressed in all +DRG2 ENSG00000108591 Developmentally regulated GTP binding protein 2 17 18087886-18107971 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007716 Approved Supported Nucleoplasm
Vesicles
Cytosol Endometrial cancer:1.56e-4 (favourable), Prostate cancer:7.34e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 29.4 Expressed in all +FTSJ3 SPB1 ENSG00000108592 FtsJ homolog 3 17 63819433-63830012 Predicted intracellular proteins Evidence at protein level HPA055544, HPA062628 Supported Enhanced Nucleoli Liver cancer:1.44e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.0 Expressed in all +AKAP10 D-AKAP2, MGC9414, PRKA10 ENSG00000108599 A-kinase anchoring protein 10 17 19904302-19978343 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028901 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all testis: 26.2 Expressed in all +ALDH3A1 ALDH3 ENSG00000108602 Aldehyde dehydrogenase 3 family member A1 17 19737984-19748943 Enzymes, Predicted intracellular proteins Evidence at protein level CAB045957, HPA051150, HPA063783 Enhanced Enhanced Vesicles
Plasma membrane
Cytosol Head and neck cancer:7.55e-5 (favourable) Mixed Group enriched 7 esophagus: 406.1;skin: 84.3;stomach: 207.2 tonsil: 31.0 Cell line enriched 21 A549: 4306.9 +SMARCD2 BAF60B, CRACD2, PRO2451, Rsc6p ENSG00000108604 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 17 63832081-63843065 Predicted intracellular proteins Evidence at protein level HPA059934, HPA061348 Enhanced Nucleoplasm Melanoma:3.51e-4 (unfavourable), Renal cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all skin: 104.6 Expressed in all +ICAM2 CD102 ENSG00000108622 Intercellular adhesion molecule 2 17 64002594-64020634 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA071155 Uncertain Cytosol Expressed in all Expressed in all spleen: 200.5 Group enriched 7 HUVEC TERT2: 1043.9;TIME: 259.9 +SYNGR2 ENSG00000108639 Synaptogyrin 2 17 78168558-78173527 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014742 Approved Approved Golgi apparatus Renal cancer:5.37e-4 (unfavourable) Expressed in all Expressed in all lung: 154.3 Mixed +B9D1 B9, EPPB9, MKS9 ENSG00000108641 B9 domain containing 1 17 19337554-19378182 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA022957 Approved Renal cancer:4.14e-4 (favourable) Expressed in all Expressed in all fallopian tube: 102.1 Mixed +UTP6 C17orf40, HCA66 ENSG00000108651 UTP6, small subunit processome component 17 31860899-31901765 Predicted intracellular proteins Evidence at protein level HPA025936, HPA055806 Enhanced Enhanced Nucleoli Renal cancer:1.16e-6 (unfavourable), Liver cancer:1.86e-5 (unfavourable) Expressed in all Expressed in all epididymis: 15.7 Expressed in all +DDX5 G17P1, HLR1, p68 ENSG00000108654 DEAD-box helicase 5 17 64499616-64508199 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005868, HPA020043 Supported Enhanced Nucleoplasm Colorectal cancer:2.12e-4 (favourable) Expressed in all Expressed in all smooth muscle: 599.5 Expressed in all +C17orf75 NJMU-R1, SRI2 ENSG00000108666 Chromosome 17 open reading frame 75 17 32324565-32350023 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004061 Approved Approved Approved Golgi apparatus
Cytosol Renal cancer:1.33e-4 (favourable), Ovarian cancer:3.13e-4 (favourable) Expressed in all Expressed in all testis: 39.6 Expressed in all +CYTH1 B2-1, cytohesin-1, D17S811E, PSCD1 ENSG00000108669 Cytohesin 1 17 78674048-78782297 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047498 Uncertain Nucleus
Nucleoli Head and neck cancer:6.48e-4 (favourable) Expressed in all Expressed in all lymph node: 92.5 Expressed in all +PSMD11 MGC3844, p44.5, Rpn6, S9 ENSG00000108671 Proteasome 26S subunit, non-ATPase 11 17 32444261-32483318 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042275, HPA067433 Approved Approved Nucleus
Golgi apparatus Renal cancer:5.73e-6 (unfavourable), Liver cancer:6.33e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 62.7 Expressed in all +LGALS3BP 90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B ENSG00000108679 Galectin 3 binding protein 17 78971238-78980109 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA000554, CAB002158 Supported Renal cancer:1.07e-6 (unfavourable) Expressed in all Expressed in all gallbladder: 323.2 Cell line enhanced SK-BR-3: 1216.4 +ASIC2 ACCN, ACCN1, ASIC2a, BNaC1, BNC1, hBNaC1, MDEG ENSG00000108684 Acid sensing ion channel subunit 2 17 33013087-34174964 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA052112 Enhanced Tissue enhanced Group enriched 6 cerebral cortex: 8.6;cervix, uterine: 3.9;endometrium: 6.4;smooth muscle: 2.2 adrenal gland: 0.8 Cell line enhanced NTERA-2: 1.1 +CCL7 FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7 ENSG00000108688 C-C motif chemokine ligand 7 17 34270221-34272242 Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Mixed Group enriched 8 appendix: 3.6;bone marrow: 15.2 gallbladder,rectum: 1.1 Cell line enhanced BJ hTERT+: 9.3;BJ hTERT+ SV40 Large T+: 2.2;BJ hTERT+ SV40 Large T+ RasG12V: 2.8;HSkMC: 2.4 +CCL2 GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF ENSG00000108691 C-C motif chemokine ligand 2 17 34255218-34257203 Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB013676, HPA019163 Approved Approved Golgi apparatus
Vesicles Renal cancer:4.51e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 411.3 Group enriched 5 BJ hTERT+: 1539.3;BJ hTERT+ SV40 Large T+ RasG12V: 503.9;HMC-1: 2137.8 +CCL8 HC14, MCP-2, SCYA8 ENSG00000108700 C-C motif chemokine ligand 8 17 34319036-34321402 Cancer-related genes, Predicted secreted proteins Evidence at protein level Renal cancer:1.05e-7 (unfavourable) Mixed Mixed adipose tissue: 13.1 Cell line enhanced EFO-21: 1.3;HSkMC: 1.4 +CCL1 I-309, P500, SCYA1, SISe, TCA3 ENSG00000108702 C-C motif chemokine ligand 1 17 34360328-34363231 Predicted secreted proteins Evidence at protein level HPA049861 Uncertain Not detected Tissue enriched 5 rectum: 2.6 cerebral cortex,testis: 0.4 Cell line enriched 50 HMC-1: 622.2 +PEX12 ENSG00000108733 Peroxisomal biogenesis factor 12 17 35574795-35578863 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA069386 Enhanced Renal cancer:3.58e-5 (favourable) Expressed in all Mixed parathyroid gland: 17.3 Mixed +KRT32 Ha-2, KRTHA2 ENSG00000108759 Keratin 32 17 41459811-41467429 Predicted intracellular proteins Evidence at protein level Not detected Group enriched 14 esophagus: 7.4;skin: 2.4 breast: 0.3 Not detected +DHX58 D11LGP2, LGP2 ENSG00000108771 DExH-box helicase 58 17 42101404-42112733 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018670, HPA019570 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Breast cancer:3.45e-4 (favourable) Expressed in all Expressed in all spleen: 24.9 Cell line enhanced BJ hTERT+ SV40 Large T+: 42.1;BJ hTERT+ SV40 Large T+ RasG12V: 51.2 +KAT2A GCN5, GCN5L2, PCAF-b ENSG00000108773 Lysine acetyltransferase 2A 17 42113108-42121358 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048958 Uncertain Renal cancer:1.41e-8 (unfavourable), Pancreatic cancer:3.57e-4 (favourable) Expressed in all Expressed in all skin: 10.9 Mixed +RAB5C RAB5CL, RABL ENSG00000108774 RAB5C, member RAS oncogene family 17 42124976-42155044 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA003426, HPA004167 Approved Enhanced Endosomes Head and neck cancer:7.08e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 180.6 Mixed +NAGLU NAG ENSG00000108784 N-acetyl-alpha-glucosaminidase 17 42536172-42544449 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038815 Supported Approved Renal cancer:2.58e-6 (favourable), Glioma:3.43e-4 (unfavourable), Endometrial cancer:4.17e-4 (favourable), Pancreatic cancer:6.90e-4 (favourable) Expressed in all Expressed in all thyroid gland: 47.5 Expressed in all +HSD17B1 EDH17B2, EDHB17, HSD17, MGC138140, SDR28C1 ENSG00000108786 Hydroxysteroid 17-beta dehydrogenase 1 17 42549214-42555213 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021032, HPA065296 Enhanced Supported Cytosol Mixed Tissue enriched 14 placenta: 98.3 cerebral cortex: 7.1 Cell line enriched 8 BEWO: 331.8 +MLX bHLHd13, MAD7, MXD7, TCFL4 ENSG00000108788 MLX, MAX dimerization protein 17 42567068-42573239 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB025329, HPA052766, HPA064438 Approved Supported Nucleoplasm
Nuclear membrane
Cytosol Expressed in all Expressed in all duodenum: 46.3 Expressed in all +CNTNAP1 Caspr, CNTNAP, NRXN4, p190 ENSG00000108797 Contactin associated protein 1 17 42682613-42699814 Disease related genes, Predicted membrane proteins Evidence at protein level HPA011772 Approved Approved Nucleoplasm Renal cancer:4.16e-14 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 61.8;smooth muscle: 38.9 endometrium: 19.2 Cell line enhanced TIME: 59.4;U-138 MG: 80.6 +ABI3 NESH, SSH3BP3 ENSG00000108798 ABI family member 3 17 49210227-49223225 Predicted intracellular proteins Evidence at protein level HPA017345 Enhanced Endometrial cancer:7.13e-4 (favourable) Expressed in all Tissue enhanced spleen: 62.0 lymph node: 29.9 Cell line enhanced Daudi: 28.2;HDLM-2: 21.3;HUVEC TERT2: 54.6;TIME: 38.1 +EZH1 KIAA0388, KMT6B ENSG00000108799 Enhancer of zeste 1 polycomb repressive complex 2 subunit 17 42700275-42745049 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA005478, HPA077684 Supported Supported Nucleoplasm Expressed in all Expressed in all ovary: 58.7 Expressed in all +DLX4 BP1, DLX7, DLX8, DLX9 ENSG00000108813 Distal-less homeobox 4 17 49968970-49974959 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059933 Uncertain Approved Nucleoplasm Mixed Tissue enhanced placenta: 5.4 skin: 1.2 Cell line enhanced BEWO: 22.0;CACO-2: 13.7;HAP1: 11.5;K-562: 12.0 +PPP1R9B PPP1R6, PPP1R9, SPINO, Spn ENSG00000108819 Protein phosphatase 1 regulatory subunit 9B 17 50133735-50150630 Predicted intracellular proteins Evidence at protein level CAB022461 Approved Pancreatic cancer:3.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 76.2 Expressed in all +COL1A1 OI4 ENSG00000108821 Collagen type I alpha 1 chain 17 50183289-50201632 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008405, HPA011795 Uncertain Approved Vesicles
Cytosol Renal cancer:7.19e-12 (unfavourable), Lung cancer:4.43e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 1872.5 Cell line enhanced BJ: 2487.8;fHDF/TERT166: 3474.4;HSkMC: 1569.1;U-138 MG: 2286.9 +SGCA A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1 ENSG00000108823 Sarcoglycan alpha 17 50164214-50175931 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007537 Uncertain Mixed Tissue enhanced heart muscle: 79.5;skeletal muscle: 181.4 seminal vesicle: 38.3 Cell line enriched 13 LHCN-M2: 65.0 +PTGES3L-AARSD1 ENSG00000108825 PTGES3L-AARSD1 readthrough 17 42950526-42980528 Predicted intracellular proteins Evidence at protein level HPA021408, HPA022869, HPA023714 Approved Approved Nuclear membrane
Cytosol Not detected Tissue enhanced smooth muscle: 7.5 testis: 4.0 Cell line enhanced THP-1: 6.4 +MRPL27 ENSG00000108826 Mitochondrial ribosomal protein L27 17 50367857-50373214 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA021416 Approved Expressed in all Expressed in all epididymis: 131.5 Expressed in all +VAT1 FLJ20230, VATI ENSG00000108828 Vesicle amine transport 1 17 43014605-43025123 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045170 Uncertain Liver cancer:1.39e-4 (unfavourable), Renal cancer:5.89e-4 (favourable) Expressed in all Expressed in all adrenal gland: 241.6 Expressed in all +LRRC59 FLJ21675, PRO1855 ENSG00000108829 Leucine rich repeat containing 59 17 50375059-50397553 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030827, HPA030829 Enhanced Enhanced Endoplasmic reticulum Renal cancer:1.19e-6 (unfavourable), Liver cancer:3.12e-6 (unfavourable), Head and neck cancer:1.00e-5 (unfavourable), Urothelial cancer:1.90e-5 (unfavourable), Colorectal cancer:2.60e-4 (favourable), Pancreatic cancer:6.87e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 92.0 Expressed in all +RND2 ARHN, Rho7, RhoN ENSG00000108830 Rho family GTPase 2 17 43025241-43032036 Predicted intracellular proteins Evidence at protein level HPA077757 Approved Group enriched Tissue enhanced cerebral cortex: 37.0;testis: 30.7 thyroid gland: 11.0 Cell line enhanced AF22: 11.9;AN3-CA: 14.4;HAP1: 12.5;NTERA-2: 17.2;SH-SY5Y: 11.0 +ALOX12 12S-LOX ENSG00000108839 Arachidonate 12-lipoxygenase, 12S type 17 6996065-7010736 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA010691, CAB019287 Approved Supported Nuclear speckles
Cytosol Mixed Group enriched 8 esophagus: 50.3;skin: 25.9 gallbladder: 5.0 Group enriched 5 A-431: 22.4;HEL: 36.7 +HDAC5 FLJ90614, KIAA0600, NY-CO-9 ENSG00000108840 Histone deacetylase 5 17 44076746-44123702 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB019400, HPA030991 Approved Supported Nuclear speckles
Golgi apparatus
Cytosol Liver cancer:3.12e-5 (unfavourable), Renal cancer:3.30e-5 (favourable), Cervical cancer:6.14e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 60.0 Mixed +ABCC3 cMOAT2, EST90757, MLP2, MOAT-D, MRP3 ENSG00000108846 ATP binding cassette subfamily C member 3 17 50634777-50692252 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB037136, HPA048483 Enhanced Approved Plasma membrane Renal cancer:4.68e-6 (unfavourable), Pancreatic cancer:9.57e-4 (unfavourable) Mixed Mixed adrenal gland: 20.7 Cell line enhanced A549: 69.8;CAPAN-2: 51.3 +LUC7L3 CRA, CREAP-1, CROP, FLJ11063, hLuc7A, LUC7A, OA48-18 ENSG00000108848 LUC7 like 3 pre-mRNA splicing factor 17 50719544-50756213 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018475, HPA018484, HPA020017 Enhanced Enhanced Nuclear speckles Renal cancer:8.41e-7 (unfavourable), Liver cancer:1.05e-5 (unfavourable), Urothelial cancer:5.35e-5 (favourable), Pancreatic cancer:6.07e-4 (favourable) Expressed in all Expressed in all endometrium: 236.1 Expressed in all +PPY PNP ENSG00000108849 Pancreatic polypeptide 17 43940804-43942468 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016735, HPA032122 Enhanced Tissue enriched Tissue enhanced pancreas: 35.3;parathyroid gland: 33.7 rectum,skin: 8.3 Cell line enhanced BEWO: 3.6;EFO-21: 3.2;U-2 OS: 4.0 +MPP2 DKFZp761D0712, DLG2 ENSG00000108852 Membrane palmitoylated protein 2 17 43875357-43909711 Predicted intracellular proteins Evidence at protein level HPA026486 Approved Approved Mitochondria
Cytosol Endometrial cancer:1.87e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 37.9;epididymis: 33.0;parathyroid gland: 43.8 testis: 24.0 Mixed +SMURF2 ENSG00000108854 SMAD specific E3 ubiquitin protein ligase 2 17 64542295-64662068 Enzymes, Predicted intracellular proteins Evidence at protein level HPA071508 Enhanced Supported Nuclear speckles Expressed in all Mixed testis: 32.9 Expressed in all +DUSP3 VHR ENSG00000108861 Dual specificity phosphatase 3 17 43766121-43778988 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063616 Supported Nucleoplasm
Cytosol Renal cancer:5.49e-5 (favourable), Head and neck cancer:3.00e-4 (unfavourable), Glioma:9.23e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 100.8 Mixed +CACNG1 CACNLG ENSG00000108878 Calcium voltage-gated channel auxiliary subunit gamma 1 17 67044590-67056797 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Tissue enhanced Tissue enriched 25 skeletal muscle: 113.4 esophagus: 4.4 Cell line enhanced HSkMC: 2.2;SH-SY5Y: 1.0 +EFTUD2 SNRNP116, Snrp116, Snu114, U5-116KD ENSG00000108883 Elongation factor Tu GTP binding domain containing 2 17 44849943-44899662 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022021 Supported Supported Nucleoplasm
Cytosol Liver cancer:2.71e-6 (unfavourable) Expressed in all Expressed in all testis: 47.7 Expressed in all +HLF MGC33822 ENSG00000108924 HLF, PAR bZIP transcription factor 17 55265012-55325065 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA068156, HPA071210 Enhanced Nucleus Lung cancer:2.71e-7 (favourable), Renal cancer:3.55e-6 (favourable), Head and neck cancer:1.88e-4 (favourable) Tissue enhanced Mixed cerebral cortex: 65.4 Group enriched 5 HDLM-2: 25.3;Hep G2: 110.7 +SLC16A6 MCT6, MCT7 ENSG00000108932 Solute carrier family 16 member 6 17 68267026-68291267 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA054459, HPA066328 Uncertain Approved Vesicles Group enriched Tissue enhanced epididymis: 39.4 esophagus: 12.1 Cell line enriched 11 SK-MEL-30: 392.2 +PRKAR1A CNC1, PRKAR1, TSE1 ENSG00000108946 Protein kinase cAMP-dependent type I regulatory subunit alpha 17 68511780-68551319 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB019378, HPA049979 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 564.4 Expressed in all +EFNB3 EPLG8, LERK-8 ENSG00000108947 Ephrin B3 17 7705202-7711378 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA001623 Approved Approved Nucleoplasm Endometrial cancer:5.52e-4 (unfavourable), Pancreatic cancer:8.21e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 48.7 endometrium: 17.4 Cell line enhanced AF22: 53.1;AN3-CA: 29.8;SH-SY5Y: 29.8 +FAM20A DKFZp434F2322 ENSG00000108950 FAM20A, golgi associated secretory pathway pseudokinase 17 68535113-68601389 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048964 Approved Renal cancer:9.16e-10 (unfavourable) Mixed Mixed lung: 8.8 Group enriched 5 ASC TERT1: 13.0;BJ hTERT+: 36.5;HSkMC: 26.3;NTERA-2: 8.0;U-2197: 11.8 +YWHAE FLJ45465 ENSG00000108953 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 17 1344272-1400378 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008445, CAB016200, CAB021109, CAB047350 Approved Uncertain Cytosol Endometrial cancer:6.48e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 451.5 Expressed in all +MMD MMA, PAQR11 ENSG00000108960 Monocyte to macrophage differentiation associated 17 55392613-55421992 Predicted membrane proteins, Transporters Evidence at transcript level HPA026978 Approved Vesicles Colorectal cancer:3.52e-5 (favourable), Liver cancer:6.39e-5 (unfavourable), Renal cancer:2.85e-4 (unfavourable), Endometrial cancer:3.88e-4 (unfavourable), Thyroid cancer:8.62e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 141.5 cerebral cortex: 73.0 Expressed in all +RANGRF HSPC165, HSPC236, MOG1, RANGNRF ENSG00000108961 RAN guanine nucleotide release factor 17 8288497-8290092 Predicted intracellular proteins Evidence at protein level HPA057280, HPA057888 Approved Supported Nucleoplasm Endometrial cancer:1.65e-4 (favourable), Pancreatic cancer:4.39e-4 (favourable) Expressed in all Expressed in all testis: 71.2 Expressed in all +DPH1 DPH2L, DPH2L1, OVCA1 ENSG00000108963 Diphthamide biosynthesis 1 17 2030110-2043430 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA069750 Approved Nucleoplasm
Cell Junctions Pancreatic cancer:1.78e-5 (favourable) Expressed in all Expressed in all fallopian tube: 31.5 Expressed in all +MAP2K6 MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3 ENSG00000108984 Mitogen-activated protein kinase kinase 6 17 69414698-69543331 Enzymes, Predicted intracellular proteins Evidence at protein level CAB007744, HPA031134 Enhanced Supported Nucleus
Cytosol Breast cancer:2.27e-6 (favourable), Pancreatic cancer:7.52e-4 (favourable) Mixed Mixed cervix, uterine: 39.1 Cell line enhanced A549: 36.5 +DHRS7B CGI-93, DKFZp566O084, MGC8916, SDR32C1 ENSG00000109016 Dehydrogenase/reductase 7B 17 21123364-21193265 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012132, HPA016873 Uncertain Approved Plasma membrane
Cell Junctions
Cytosol Endometrial cancer:1.98e-8 (favourable), Renal cancer:3.95e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 51.2 Expressed in all +WSB1 DKFZp564A122, DKFZp564B0482, SWIP1 ENSG00000109046 WD repeat and SOCS box containing 1 17 27294076-27315926 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003293 Approved Approved Mitochondria Renal cancer:1.02e-7 (unfavourable), Liver cancer:4.07e-5 (unfavourable) Expressed in all Expressed in all placenta: 107.4 Expressed in all +RCVRN RCV1 ENSG00000109047 Recoverin 17 9896320-9905621 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015783, CAB022363 Supported Not detected Not detected cerebral cortex: 0.3 Cell line enriched 7 WM-115: 2.3 +MYH1 MGC133384, MYHa, MyHC-2X/D, MYHSA1 ENSG00000109061 Myosin heavy chain 1 17 10492307-10518543 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001349, CAB010759 Enhanced Tissue enriched Tissue enriched 738 skeletal muscle: 2753.9 esophagus: 3.7 Not detected +SLC9A3R1 EBP50, NHERF ENSG00000109062 SLC9A3 regulator 1 17 74748652-74769353 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level CAB001962, HPA009672, HPA027247 Enhanced Approved Vesicles
Plasma membrane
Microtubule organizing center Liver cancer:9.83e-5 (unfavourable) Expressed in all Expressed in all small intestine: 302.4 Expressed in all +MYH3 HEMHC, MYHC-EMB, MYHSE1, SMHCE ENSG00000109063 Myosin heavy chain 3 17 10628526-10657309 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021808 Enhanced Mixed Group enriched 7 esophagus: 9.7;prostate: 46.3;seminal vesicle: 24.5 testis,urinary bladder: 4.0 Cell line enriched 30 HSkMC: 43.3 +NAT9 DKFZP564C103 ENSG00000109065 N-acetyltransferase 9 (putative) 17 74770547-74776367 Predicted intracellular proteins Evidence at protein level HPA021820, HPA057149 Approved Approved Nucleoplasm Renal cancer:6.26e-6 (unfavourable), Pancreatic cancer:3.21e-5 (favourable), Liver cancer:3.25e-5 (unfavourable), Stomach cancer:7.80e-4 (favourable) Expressed in all Expressed in all adrenal gland: 39.1 Expressed in all +TMEM104 FLJ00021, FLJ20255 ENSG00000109066 Transmembrane protein 104 17 74776483-74839779 Predicted membrane proteins, Transporters Evidence at protein level HPA044330 Approved Approved Nucleoplasm
Golgi apparatus Pancreatic cancer:1.97e-5 (favourable), Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 15.0 Expressed in all +VTN VN ENSG00000109072 Vitronectin 17 28367276-28373091 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB016695, CAB016765, HPA060933 Supported Supported Endoplasmic reticulum
Vesicles Renal cancer:4.10e-11 (unfavourable), Liver cancer:3.74e-4 (favourable) Tissue enriched Tissue enriched 28 liver: 2554.5 gallbladder: 91.2 Cell line enriched 9 CACO-2: 1044.7 +TNFAIP1 B12, B61, BTBD34, EDP1, MGC2317 ENSG00000109079 TNF alpha induced protein 1 17 28335602-28347009 Predicted intracellular proteins Evidence at protein level HPA013333, HPA014641 Uncertain Enhanced Nucleoli Endometrial cancer:7.48e-5 (unfavourable) Expressed in all Expressed in all spleen: 69.1 Expressed in all +IFT20 ENSG00000109083 Intraflagellar transport 20 17 28328325-28335489 Predicted intracellular proteins Evidence at protein level HPA021376 Approved Approved Microtubules Renal cancer:5.09e-7 (unfavourable), Liver cancer:1.96e-4 (unfavourable), Endometrial cancer:8.65e-4 (unfavourable) Expressed in all Expressed in all testis: 79.8 Expressed in all +TMEM97 MAC30 ENSG00000109084 Transmembrane protein 97 17 28319095-28328685 Predicted membrane proteins Evidence at protein level HPA044795 Approved Approved Nuclear membrane
Plasma membrane
Cytosol Renal cancer:1.24e-4 (unfavourable) Expressed in all Expressed in all testis: 110.0 Expressed in all +CDR2L HUMPPA ENSG00000109089 Cerebellar degeneration related protein 2 like 17 74987632-75005800 Predicted intracellular proteins Evidence at protein level HPA022015 Enhanced Approved Cytosol Expressed in all Mixed duodenum: 22.5 Mixed +PMP22 GAS3, HNPP, Sp110 ENSG00000109099 Peripheral myelin protein 22 17 15229777-15265326 Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all placenta: 316.4 Cell line enhanced ASC diff: 277.3;HMC-1: 278.9;WM-115: 491.1 +FOXN1 FKHL20, RONU, WHN ENSG00000109101 Forkhead box N1 17 28506243-28538896 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Head and neck cancer:5.00e-4 (favourable), Cervical cancer:6.43e-4 (favourable) Tissue enhanced Tissue enhanced esophagus: 7.2;skin: 35.2 tonsil: 5.1 Cell line enriched 8 HaCaT: 10.3 +UNC119 HRG4, POC7, POC7A ENSG00000109103 Unc-119 lipid binding chaperone 17 28546707-28552668 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041912 Supported Pancreatic cancer:8.09e-5 (favourable), Melanoma:2.38e-4 (unfavourable), Thyroid cancer:9.82e-4 (unfavourable) Expressed in all Expressed in all testis: 45.5 Expressed in all +ALDOC ENSG00000109107 Aldolase, fructose-bisphosphate C 17 28573115-28577264 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003282, CAB020828, HPA067442 Enhanced Supported Approved Nucleus
Nucleoli fibrillar center
Vesicles
Cytosol Renal cancer:1.29e-7 (unfavourable), Head and neck cancer:9.80e-4 (unfavourable) Tissue enriched Tissue enriched 7 cerebral cortex: 766.6 heart muscle: 111.2 Cell line enhanced RPMI-8226: 165.2;U-266/70: 119.9 +SUPT6H KIAA0162, SPT6H ENSG00000109111 SPT6 homolog, histone chaperone 17 28662091-28702684 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012416, HPA036382 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:3.68e-5 (unfavourable), Renal cancer:4.36e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 62.1 Expressed in all +RAB34 NARR, RAB39, RAH ENSG00000109113 RAB34, member RAS oncogene family 17 28714281-28718429 Predicted intracellular proteins Evidence at protein level HPA021366 Approved Renal cancer:1.64e-7 (unfavourable), Thyroid cancer:1.06e-5 (favourable) Expressed in all Mixed endometrium: 122.5 Mixed +PHF12 KIAA1523, PF1 ENSG00000109118 PHD finger protein 12 17 28905250-28951771 Predicted intracellular proteins Evidence at protein level HPA021410, HPA021452 Approved Enhanced Nucleoplasm Renal cancer:1.24e-5 (unfavourable) Expressed in all Expressed in all prostate: 28.8 Expressed in all +PHOX2B NBPhox, Phox2b, PMX2B ENSG00000109132 Paired like homeobox 2b 4 41744082-41748970 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA074325, HPA074941 Enhanced Nucleoplasm Not detected Tissue enriched 8 adrenal gland: 10.3 small intestine: 1.2 Cell line enriched 92 SH-SY5Y: 130.2 +TMEM33 FLJ10525 ENSG00000109133 Transmembrane protein 33 4 41935120-41960572 Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:1.35e-5 (favourable) Expressed in all Expressed in all thyroid gland: 39.9 Expressed in all +GABRA4 ENSG00000109158 Gamma-aminobutyric acid type A receptor alpha4 subunit 4 46918900-46994407 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 9 cerebral cortex: 15.1 heart muscle: 1.6 Cell line enriched 127 REH: 12.7 +GNRHR GRHR, LHRHR ENSG00000109163 Gonadotropin releasing hormone receptor 4 67739328-67754360 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA013424 Supported Not detected Tissue enhanced adrenal gland: 1.0 cerebral cortex: 0.6 Not detected +SLAIN2 FLJ21611, KIAA1458 ENSG00000109171 SLAIN motif family member 2 4 48341322-48426212 Predicted intracellular proteins Evidence at protein level HPA035824, HPA063599 Approved Enhanced Centrosome
Cytosol Renal cancer:1.50e-4 (favourable), Colorectal cancer:5.77e-4 (favourable), Pancreatic cancer:6.71e-4 (unfavourable), Endometrial cancer:7.98e-4 (favourable) Expressed in all Expressed in all testis: 72.9 Expressed in all +OCIAD1 Asrij, FLJ20455, OCIA, TPA018 ENSG00000109180 OCIA domain containing 1 4 48805212-48861817 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044803 Approved Approved Mitochondria Expressed in all Expressed in all cerebral cortex: 325.6 Expressed in all +UGT2B10 ENSG00000109181 UDP glucuronosyltransferase family 2 member B10 4 68815993-68831196 Enzymes, Predicted membrane proteins Evidence at protein level HPA045108 Uncertain Tissue enriched Tissue enriched 87 liver: 304.0 gallbladder: 3.4 Cell line enriched 33 Hep G2: 7.9 +CWH43 CWH43-C, FLJ21511 ENSG00000109182 Cell wall biogenesis 43 C-terminal homolog 4 48986247-49062081 Predicted membrane proteins Evidence at protein level HPA042814, HPA048140 Uncertain Renal cancer:2.29e-11 (favourable), Endometrial cancer:1.32e-4 (favourable) Tissue enhanced Tissue enhanced prostate: 67.5 skin: 29.6 Not detected +DCUN1D4 KIAA0276 ENSG00000109184 Defective in cullin neddylation 1 domain containing 4 4 51843000-51916837 Predicted intracellular proteins Evidence at protein level HPA036483, HPA036484 Uncertain Supported Nucleus
Vesicles Expressed in all Expressed in all testis: 28.9 Expressed in all +USP46 FLJ12552 ENSG00000109189 Ubiquitin specific peptidase 46 4 52590972-52659335 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007288, CAB076369, CAB076370 Uncertain Enhanced Nucleoli Expressed in all Expressed in all cerebral cortex: 44.7 Mixed +SULT1E1 EST, STE ENSG00000109193 Sulfotransferase family 1E member 1 4 69810780-69860152 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA028213, HPA028728, CAB047344 Enhanced Uncertain Nuclear membrane
Cytosol Cervical cancer:4.06e-4 (favourable) Mixed Group enriched 7 duodenum: 27.7;liver: 18.7;skin: 7.6;small intestine: 29.7 adrenal gland: 3.1 Group enriched 17 HHSteC: 59.4;HSkMC: 23.3;hTCEpi: 19.7;HUVEC TERT2: 16.9 +ODAM APin, FLJ20513 ENSG00000109205 Odontogenic, ameloblast asssociated 4 70196496-70204576 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036543 Supported Nucleoplasm
Cytosol Mixed Tissue enriched 13 salivary gland: 136.2 smooth muscle: 10.1 Cell line enriched 13 Hep G2: 21.4 +SMR3A PBI, PRL5, PROL5 ENSG00000109208 Submaxillary gland androgen regulated protein 3A 4 70360761-70367158 Predicted secreted proteins Evidence at protein level HPA044567 Enhanced Tissue enhanced Tissue enriched 24 salivary gland: 24.1 thyroid gland: 0.9 Not detected +CHIC2 BTL ENSG00000109220 Cysteine rich hydrophobic domain 2 4 54009789-54064690 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026782, HPA026784, HPA076603 Uncertain Enhanced Vesicles
Plasma membrane Renal cancer:1.56e-4 (unfavourable) Expressed in all Expressed in all testis: 63.2 Expressed in all +NMU ENSG00000109255 Neuromedin U 4 55595229-55636698 Predicted secreted proteins Evidence at protein level HPA025926 Uncertain Renal cancer:4.07e-10 (unfavourable), Endometrial cancer:2.60e-5 (unfavourable) Mixed Group enriched 6 esophagus: 34.9;skin: 45.4 tonsil: 6.8 Cell line enhanced HaCaT: 336.7;K-562: 278.2 +KIAA1211 ENSG00000109265 KIAA1211 4 56049073-56328625 Predicted intracellular proteins Evidence at protein level HPA043249, HPA048148 Uncertain Approved Nucleoplasm
Golgi apparatus Mixed Tissue enhanced testis: 39.9 small intestine: 23.1 Cell line enhanced SCLC-21H: 37.8;SH-SY5Y: 72.8 +LAMTOR3 MAP2K1IP1, MAPBP, MAPKSP1, MP1, Ragulator3 ENSG00000109270 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 4 99878336-99894490 Predicted intracellular proteins Evidence at protein level HPA026858 Supported Renal cancer:1.75e-9 (favourable), Liver cancer:2.09e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 57.3 Expressed in all +PF4V1 CXCL4L1, CXCL4V1, SCYB4V1 ENSG00000109272 Platelet factor 4 variant 1 4 73853189-73854155 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA052485 Supported Tissue enhanced Tissue enhanced spleen: 3.9 urinary bladder: 2.8 Cell line enhanced CAPAN-2: 1.2;EFO-21: 2.0 +NFKB1 KBF1, NF-kappaB, NF-kB1, NFkappaB, NFKB-p50, p105, p50 ENSG00000109320 Nuclear factor kappa B subunit 1 4 102501329-102617302 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level CAB004031, HPA027305 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:1.76e-4 (favourable) Expressed in all Expressed in all bone marrow: 56.9 Expressed in all +AREG AREGB, SDGF ENSG00000109321 Amphiregulin 4 74445134-74455009 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA008720, CAB023519 Approved Approved Mitochondria Lung cancer:1.05e-5 (unfavourable), Head and neck cancer:2.61e-5 (unfavourable), Pancreatic cancer:8.32e-5 (unfavourable) Expressed in all Tissue enhanced placenta: 463.5 gallbladder: 119.8 Cell line enhanced CACO-2: 310.7;HBEC3-KT: 461.5;hTCEpi: 463.0;hTERT-HME1: 1044.5;MCF7: 315.9 +MANBA ENSG00000109323 Mannosidase beta 4 102631488-102760994 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA053478 Approved Supported Vesicles Liver cancer:3.74e-6 (unfavourable), Glioma:1.06e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 37.4 Expressed in all +UBE2D3 UbcH5C ENSG00000109332 Ubiquitin conjugating enzyme E2 D3 4 102794383-102868896 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003920 Uncertain Approved Plasma membrane
Cytosol Renal cancer:4.51e-4 (favourable) Expressed in all Expressed in all bone marrow: 300.9 Expressed in all +MAPK10 JNK3, p493F12, p54bSAPK, PRKM10 ENSG00000109339 Mitogen-activated protein kinase 10 4 86010395-86594131 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB022625 Approved Renal cancer:3.11e-4 (favourable), Urothelial cancer:5.57e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 113.0 seminal vesicle: 38.6 Cell line enriched 16 AF22: 181.7 +ELF2 EU32, NERF, NERF-1A, NERF-1B, NERF-2 ENSG00000109381 E74 like ETS transcription factor 2 4 139028112-139177218 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006057, HPA071166 Enhanced Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all testis: 69.4 Expressed in all +NDUFC1 KFYI ENSG00000109390 NADH:ubiquinone oxidoreductase subunit C1 4 139266880-139302551 Predicted membrane proteins Evidence at protein level HPA044556 Approved Supported Mitochondria Endometrial cancer:8.23e-5 (favourable), Urothelial cancer:7.25e-4 (favourable), Renal cancer:9.96e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 86.7 Expressed in all +UCP1 SLC25A7, UCP ENSG00000109424 Uncoupling protein 1 4 140559434-140568805 Predicted membrane proteins, Transporters Evidence at protein level Tissue enhanced Tissue enhanced adrenal gland: 3.7 breast: 0.9 Group enriched 16 BEWO: 4.9;HAP1: 3.8 +TBC1D9 GRAMD9, KIAA0882, MDR1 ENSG00000109436 TBC1 domain family member 9 4 140620765-140756120 Predicted intracellular proteins Evidence at protein level HPA000262, HPA006317, HPA006503 Uncertain Supported Approved Nucleoplasm
Cytosol Renal cancer:1.61e-6 (favourable) Tissue enriched Mixed breast: 65.6 Mixed +ZNF330 HSA6591, NOA36 ENSG00000109445 Zinc finger protein 330 4 141220887-141234697 Predicted intracellular proteins Evidence at protein level HPA015705, HPA056325 Uncertain Supported Nucleoli Prostate cancer:3.66e-6 (unfavourable), Renal cancer:7.27e-6 (favourable) Expressed in all Expressed in all heart muscle: 68.3 Expressed in all +INPP4B ENSG00000109452 Inositol polyphosphate-4-phosphatase type II B 4 142023160-142847432 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA037681, HPA037682 Approved Approved Centrosome Pancreatic cancer:1.03e-4 (unfavourable) Mixed Mixed testis: 33.2 Cell line enhanced CAPAN-2: 132.1 +GAB1 ENSG00000109458 GRB2 associated binding protein 1 4 143336762-143474568 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB034333, HPA049599 Enhanced Approved Vesicles Renal cancer:3.91e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 32.2 Cell line enhanced REH: 67.9 +KLHL2 MAV ENSG00000109466 Kelch like family member 2 4 165207618-165323156 Predicted intracellular proteins Evidence at protein level HPA051637 Uncertain Nucleoplasm
Vesicles Renal cancer:3.77e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 77.5 thyroid gland: 22.0 Mixed +IL2 IL-2, TCGF ENSG00000109471 Interleukin 2 4 122451470-122456725 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB010310 Uncertain Not detected Not detected rectum,small intestine,tonsil: 0.3 Not detected +CPE ENSG00000109472 Carboxypeptidase E 4 165361194-165498320 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003819, CAB024907 Supported Approved Nucleoplasm
Vesicles
Centrosome Urothelial cancer:2.12e-4 (unfavourable), Renal cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1560.8 Group enriched 5 Hep G2: 211.8;SCLC-21H: 493.5;SH-SY5Y: 147.0;SiHa: 668.1 +RPL34 L34 ENSG00000109475 Ribosomal protein L34 4 108620566-108630412 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA035139 Uncertain Supported Nucleoli
Endoplasmic reticulum
Cytosol Endometrial cancer:2.76e-5 (favourable) Expressed in all Expressed in all breast: 4622.0 Expressed in all +WFS1 DFNA14, DFNA38, DFNA6, DIDMOAD, WFS ENSG00000109501 Wolframin ER transmembrane glycoprotein 4 6269849-6303265 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA029128 Approved Endometrial cancer:1.13e-6 (favourable), Thyroid cancer:3.13e-4 (unfavourable) Expressed in all Mixed ovary: 61.5 Cell line enhanced BEWO: 97.0 +ANXA10 ANX14 ENSG00000109511 Annexin A10 4 168092515-168187690 Predicted intracellular proteins Evidence at protein level HPA005469 Enhanced Approved Nucleus
Nucleoli
Vesicles Liver cancer:3.64e-6 (favourable) Group enriched Tissue enriched 8 stomach: 459.7 urinary bladder: 60.6 Group enriched 8 PC-3: 118.8;RT4: 140.1 +GRPEL1 FLJ25609, GrpE, hMGE ENSG00000109519 GrpE like 1, mitochondrial 4 7058906-7068197 Predicted intracellular proteins Evidence at protein level HPA036647 Supported Supported Mitochondria Renal cancer:2.00e-6 (favourable) Expressed in all Expressed in all adrenal gland: 43.9 Expressed in all +GAR1 NOLA1 ENSG00000109534 GAR1 ribonucleoprotein 4 109815510-109824740 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059098 Supported Supported Nucleus
Nucleoli fibrillar center Liver cancer:2.64e-5 (unfavourable) Expressed in all Expressed in all breast: 23.0 Expressed in all +FRG1 FRG1A, FSG1 ENSG00000109536 FSHD region gene 1 4 189940788-189963204 Disease related genes, Predicted intracellular proteins Evidence at protein level Stomach cancer:9.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 12.5 Expressed in all +CLCN3 ClC-3, CLC3 ENSG00000109572 Chloride voltage-gated channel 3 4 169612633-169723673 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044723 Approved Approved Cytosol Renal cancer:1.10e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 104.1 Expressed in all +AADAT KAT2, KATII, KYAT2 ENSG00000109576 Aminoadipate aminotransferase 4 170060222-170091699 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037502 Enhanced Approved Vesicles
Plasma membrane Colorectal cancer:5.59e-4 (favourable) Expressed in all Tissue enhanced liver: 34.7 prostate: 23.4 Mixed +GALNT7 GALNAC-T7 ENSG00000109586 Polypeptide N-acetylgalactosaminyltransferase 7 4 173168753-173323967 Predicted intracellular proteins Evidence at protein level HPA064243, HPA065317 Enhanced Enhanced Nucleus
Golgi apparatus Colorectal cancer:4.53e-4 (favourable), Pancreatic cancer:7.65e-4 (unfavourable) Expressed in all Mixed stomach: 62.9 Mixed +DHX15 DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p ENSG00000109606 DEAH-box helicase 15 4 24517441-24584550 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047047 Approved Enhanced Nuclear speckles Colorectal cancer:5.74e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 102.7 Expressed in all +SOD3 EC-SOD ENSG00000109610 Superoxide dismutase 3 4 24789912-24800842 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA042110 Supported Expressed in all Tissue enhanced adipose tissue: 179.2 fallopian tube: 66.5 Cell line enhanced ASC diff: 41.5;PC-3: 46.6;RPTEC TERT1: 158.1 +SEPSECS SLA, SLA/LP ENSG00000109618 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 4 25120014-25160442 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA070409 Approved Vesicles Expressed in all Expressed in all liver: 16.7 Expressed in all +CPZ ENSG00000109625 Carboxypeptidase Z 4 8592660-8619759 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced ovary: 121.5 placenta: 58.0 Cell line enhanced BEWO: 63.6;BJ: 32.8;BJ hTERT+: 42.2;RH-30: 54.5;U-2197: 38.2 +TRIM2 CMT2R, KIAA0517, RNF86 ENSG00000109654 Tripartite motif containing 2 4 153152342-153339320 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035853, HPA035854 Enhanced Approved Centrosome Renal cancer:6.58e-14 (favourable) Expressed in all Tissue enhanced cerebral cortex: 155.1 thyroid gland: 110.7 Cell line enhanced AF22: 68.3 +SLC2A9 Glut9, GLUTX, URATv1 ENSG00000109667 Solute carrier family 2 member 9 4 9771153-10054936 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA066229 Enhanced Renal cancer:1.32e-11 (favourable) Mixed Tissue enhanced kidney: 30.8;seminal vesicle: 27.2 placenta: 11.1 Cell line enhanced HBEC3-KT: 34.8;Hep G2: 16.1;hTCEpi: 14.4;THP-1: 13.9;U-937: 10.7 +FBXW7 AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10 ENSG00000109670 F-box and WD repeat domain containing 7 4 152321259-152536101 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB013793, CAB029987 Supported Supported Nucleoplasm
Vesicles Renal cancer:1.52e-4 (unfavourable) Expressed in all Expressed in all skin: 87.4 Expressed in all +NEIL3 FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3 ENSG00000109674 Nei like DNA glycosylase 3 4 177309836-177362943 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065761 Enhanced Nucleoplasm Lung cancer:1.16e-4 (unfavourable), Endometrial cancer:5.45e-4 (unfavourable) Mixed Mixed bone marrow: 4.3 Mixed +TBC1D19 FLJ11082 ENSG00000109680 TBC1 domain family member 19 4 26576437-26755351 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039592 Approved Approved Nucleoplasm
Nuclear membrane Renal cancer:1.21e-7 (favourable), Thyroid cancer:4.06e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 23.2 Cell line enhanced LHCN-M2: 64.6 +CLNK MIST ENSG00000109684 Cytokine dependent hematopoietic cell linker 4 10486395-10684865 Predicted intracellular proteins Evidence at protein level HPA035671, HPA035672 Uncertain Uncertain Vesicles Tissue enriched Tissue enhanced kidney: 5.8 lymph node: 3.4 Group enriched 6 HDLM-2: 3.9;U-937: 1.6 +NSD2 KMT3G, MMSET, WHSC1 ENSG00000109685 Nuclear receptor binding SET domain protein 2 4 1871424-1982207 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015801, CAB068246, CAB068247 Enhanced Supported Nucleus Liver cancer:2.61e-4 (unfavourable), Renal cancer:7.19e-4 (unfavourable) Expressed in all Expressed in all testis: 66.6 Expressed in all +SH3D19 DKFZp434D0215, EBP, EVE1, Kryn, SH3P19 ENSG00000109686 SH3 domain containing 19 4 151102751-151325632 Predicted intracellular proteins Evidence at protein level HPA016424, HPA058562 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:1.38e-5 (favourable) Expressed in all Mixed gallbladder: 99.5 Cell line enhanced ASC diff: 130.5;ASC TERT1: 113.0 +STIM2 ENSG00000109689 Stromal interaction molecule 2 4 26857678-27025381 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA036933, CAB037196, HPA057511 Supported Liver cancer:3.97e-5 (unfavourable), Pancreatic cancer:5.01e-4 (favourable) Expressed in all Expressed in all gallbladder: 45.8 Expressed in all +NKX3-2 BAPX1, NKX3.2, NKX3B ENSG00000109705 NK3 homeobox 2 4 13540830-13545050 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA027564 Approved Approved Nucleoplasm Mixed Tissue enhanced spleen: 2.7 smooth muscle: 1.6 Cell line enhanced HAP1: 3.6;NB-4: 6.2;NTERA-2: 5.3;THP-1: 3.9 +MFSD10 IT10C3, TETRAN ENSG00000109736 Major facilitator superfamily domain containing 10 4 2930561-2934859 Predicted membrane proteins Evidence at protein level HPA043209 Uncertain Approved Nucleoplasm
Nuclear membrane Renal cancer:5.68e-5 (unfavourable), Liver cancer:4.49e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 41.2 Expressed in all +GLRB ENSG00000109738 Glycine receptor beta 4 157076057-157172090 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA052363 Approved Renal cancer:4.89e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 62.0;parathyroid gland: 63.1 cervix, uterine: 14.1 Mixed +BST1 CD157 ENSG00000109743 Bone marrow stromal cell antigen 1 4 15702950-15738313 CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA050121 Uncertain Expressed in all Tissue enhanced bone marrow: 105.5 duodenum: 54.8 Cell line enhanced THP-1: 60.3;TIME: 39.6;U-937: 45.8;WM-115: 51.6 +RAPGEF2 DKFZP586O1422, KIAA0313, PDZ-GEF1, PDZGEF1, RA-GEF ENSG00000109756 Rap guanine nucleotide exchange factor 2 4 159104178-159360169 Predicted intracellular proteins Evidence at protein level HPA057169 Supported Nucleoplasm
Vesicles
Centrosome Renal cancer:1.76e-7 (favourable) Expressed in all Expressed in all thyroid gland: 109.8 Mixed +HGFAC HGFA, HGFAP ENSG00000109758 HGF activator 4 3441887-3449495 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA058279, HPA059076 Enhanced Renal cancer:9.31e-4 (unfavourable) Tissue enriched Tissue enriched 14 liver: 28.6 testis: 2.0 Cell line enriched 6 Hep G2: 3.6 +SNX25 SBBI31 ENSG00000109762 Sorting nexin 25 4 185204237-185370185 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA036928 Supported Vesicles Expressed in all Expressed in all lung: 42.7 Expressed in all +LRP2BP DKFZp761O0113 ENSG00000109771 LRP2 binding protein 4 185363879-185395899 Predicted intracellular proteins Evidence at protein level HPA036664, HPA036665 Approved Mixed Tissue enhanced fallopian tube: 12.3;testis: 20.3 cerebral cortex: 6.3 Cell line enhanced U-266/70: 4.7 +UFSP2 C4orf20, FLJ11200 ENSG00000109775 UFM1 specific peptidase 2 4 185399540-185425985 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039985, HPA043298 Approved Approved Nucleus
Cytosol Renal cancer:1.07e-8 (favourable) Expressed in all Expressed in all thyroid gland: 53.0 Expressed in all +KLF3 BKLF ENSG00000109787 Kruppel like factor 3 4 38664196-38701042 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049512, HPA065054 Supported Enhanced Nucleoplasm Renal cancer:4.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 63.1 Mixed +KLHL5 ENSG00000109790 Kelch like family member 5 4 39045039-39126857 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013958 Approved Expressed in all Expressed in all seminal vesicle: 91.0 Expressed in all +FAM149A DKFZP564J102, MST119, MSTP119 ENSG00000109794 Family with sequence similarity 149 member A 4 186104419-186172667 Predicted intracellular proteins Evidence at protein level HPA044019, HPA055004 Uncertain Approved Golgi apparatus Endometrial cancer:2.67e-6 (favourable) Mixed Mixed kidney: 37.1 Cell line enhanced ASC diff: 7.6;RT4: 7.7;SCLC-21H: 16.7 +NCAPG CAP-G, FLJ12450, hCAP-G, YCG1 ENSG00000109805 Non-SMC condensin I complex subunit G 4 17810902-17844862 Predicted intracellular proteins Evidence at protein level HPA039613 Uncertain Liver cancer:3.13e-6 (unfavourable), Pancreatic cancer:7.65e-5 (unfavourable), Endometrial cancer:8.28e-4 (unfavourable) Mixed Mixed lymph node,testis: 9.9 Mixed +UGDH ENSG00000109814 UDP-glucose 6-dehydrogenase 4 39498755-39528311 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034444, HPA036656, HPA036657 Enhanced Enhanced Nucleoplasm Renal cancer:5.51e-10 (unfavourable) Expressed in all Expressed in all colon: 95.4 Expressed in all +PPARGC1A PGC-1alpha, PGC1, PGC1A, PPARGC1 ENSG00000109819 PPARG coactivator 1 alpha 4 23755041-23904089 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA063136 Supported Nucleoplasm Renal cancer:1.49e-14 (favourable), Liver cancer:3.35e-6 (favourable), Thyroid cancer:5.80e-4 (unfavourable) Tissue enhanced Mixed kidney,parathyroid gland: 29.2 Cell line enriched 8 A-431: 76.6 +DDX25 GRTH ENSG00000109832 DEAD-box helicase 25 11 125903348-125943702 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020137 Enhanced Tissue enhanced Group enriched 12 cerebral cortex: 34.6;testis: 163.8 thyroid gland: 8.0 Cell line enhanced NTERA-2: 10.8;SCLC-21H: 10.2 +CRYAB CRYA2, HSPB5 ENSG00000109846 Crystallin alpha B 11 111908565-111923722 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002053, CAB040560, HPA057100 Enhanced Enhanced Plasma membrane
Cytosol Urothelial cancer:1.70e-5 (unfavourable), Colorectal cancer:4.90e-5 (unfavourable) Group enriched Tissue enhanced heart muscle: 3968.4 cerebral cortex: 1888.7 Cell line enhanced ASC diff: 1679.2;fHDF/TERT166: 650.9;U-138 MG: 315.9 +DBX1 ENSG00000109851 Developing brain homeobox 1 11 20156155-20160613 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA039802 Uncertain Not detected Not detected testis: 0.2 Cell line enriched 9 NTERA-2: 1.0 +HTATIP2 CC3, FLJ26963, SDR44U1, TIP30 ENSG00000109854 HIV-1 Tat interactive protein 2 11 20363685-20383783 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA006417, HPA024321 Approved Supported Cytosol Liver cancer:2.86e-4 (unfavourable), Pancreatic cancer:6.18e-4 (unfavourable), Renal cancer:8.01e-4 (unfavourable) Expressed in all Expressed in all duodenum: 135.2 Mixed +CTSC DPP1, PALS, PLS ENSG00000109861 Cathepsin C 11 88293592-88337787 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025364, HPA066610, HPA068434 Enhanced Supported Vesicles Liver cancer:9.30e-5 (unfavourable), Renal cancer:4.80e-4 (favourable) Expressed in all Expressed in all lung: 390.4 Expressed in all +CCDC34 L15, NY-REN-41, RAMA3 ENSG00000109881 Coiled-coil domain containing 34 11 27330827-27363868 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037574 Uncertain Approved Nuclear membrane
Nucleoli fibrillar center Liver cancer:1.32e-7 (unfavourable), Renal cancer:1.82e-4 (unfavourable), Ovarian cancer:8.52e-4 (favourable) Expressed in all Tissue enhanced testis: 54.8 fallopian tube: 13.4 Expressed in all +ZBTB16 PLZF, ZNF145 ENSG00000109906 Zinc finger and BTB domain containing 16 11 114059593-114250676 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001499, CAB004540 Uncertain Renal cancer:2.21e-4 (favourable) Tissue enhanced Mixed ovary: 59.5 Cell line enhanced ASC diff: 40.2;ASC TERT1: 23.6;HEL: 33.4;HHSteC: 21.2;HSkMC: 19.6;hTCEpi: 18.6;hTERT-HME1: 17.2 +ELP4 C11orf19, PAXNEB ENSG00000109911 Elongator acetyltransferase complex subunit 4 11 31509700-31790328 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038572, HPA038573 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 15.4 Expressed in all +ZPR1 ZNF259 ENSG00000109917 ZPR1 zinc finger 11 116773799-116788050 Predicted intracellular proteins Evidence at protein level CAB022596, HPA030979 Uncertain Approved Vesicles Liver cancer:5.87e-6 (unfavourable), Head and neck cancer:8.01e-4 (unfavourable) Expressed in all Expressed in all testis: 43.9 Expressed in all +MTCH2 SLC25A50 ENSG00000109919 Mitochondrial carrier 2 11 47617315-47642623 Predicted membrane proteins, Transporters Evidence at protein level HPA038390 Approved Supported Mitochondria Renal cancer:9.05e-6 (favourable) Expressed in all Expressed in all testis: 138.3 Expressed in all +FNBP4 KIAA1014 ENSG00000109920 Formin binding protein 4 11 47716517-47767443 Predicted intracellular proteins Evidence at protein level HPA039485, HPA040029 Supported Enhanced Nuclear speckles Renal cancer:1.91e-8 (unfavourable), Urothelial cancer:7.23e-5 (favourable), Liver cancer:7.33e-5 (unfavourable), Melanoma:2.50e-4 (unfavourable), Prostate cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all spleen: 48.1 Expressed in all +TECTA DFNA12, DFNA8, DFNB21 ENSG00000109927 Tectorin alpha 11 121101173-121191493 Disease related genes, Predicted membrane proteins Evidence at protein level HPA018870 Approved Mixed Tissue enhanced cerebral cortex: 2.7 parathyroid gland: 2.0 Cell line enhanced SH-SY5Y: 1.5 +SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase 11 121292453-121308694 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA066283, HPA070248 Approved Approved Nucleoplasm
Endoplasmic reticulum
Plasma membrane
Cytosol Renal cancer:1.07e-7 (favourable), Head and neck cancer:3.30e-4 (unfavourable), Melanoma:3.98e-4 (unfavourable) Expressed in all Expressed in all liver: 193.5 Expressed in all +CRTAM CD355 ENSG00000109943 Cytotoxic and regulatory T-cell molecule 11 122838500-122872639 CD markers, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced lymph node: 9.8 spleen: 5.0 Cell line enriched 45 SCLC-21H: 15.2 +C11orf63 FLJ23554 ENSG00000109944 Chromosome 11 open reading frame 63 11 122882528-122959798 Predicted intracellular proteins Evidence at protein level HPA039612, HPA040344, HPA077658, HPA077748 Enhanced Supported Nucleoplasm
Golgi apparatus Endometrial cancer:7.94e-5 (favourable), Thyroid cancer:2.58e-4 (unfavourable), Renal cancer:8.77e-4 (favourable) Mixed Tissue enhanced testis: 63.8 parathyroid gland: 14.8 Mixed +B3GAT1 CD57, GlcAT-P, HNK-1, LEU7, NK-1 ENSG00000109956 Beta-1,3-glucuronyltransferase 1 11 134378504-134411918 Enzymes, Predicted intracellular proteins Evidence at protein level CAB002500, CAB010893, HPA069468 Enhanced Supported Vesicles Group enriched Tissue enriched 11 cerebral cortex: 115.4 thyroid gland: 10.3 Cell line enhanced AF22: 22.9;HMC-1: 22.4;NTERA-2: 22.3;SH-SY5Y: 9.0 +HSPA8 HSC70, HSC71, HSP73, HSPA10 ENSG00000109971 Heat shock protein family A (Hsp70) member 8 11 123057489-123063230 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002056, HPA052504 Uncertain Approved Nucleoplasm
Vesicles Colorectal cancer:6.14e-6 (favourable), Liver cancer:1.93e-4 (unfavourable), Renal cancer:3.81e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1119.0 Expressed in all +P2RX3 P2X3 ENSG00000109991 Purinergic receptor P2X 3 11 57338374-57370600 Predicted membrane proteins, Transporters Evidence at protein level HPA057776 Uncertain Not detected Tissue enhanced heart muscle: 2.5;testis: 6.1 liver: 0.9 Not detected +VWA5A BCSC-1, LOH11CR2A ENSG00000110002 Von Willebrand factor A domain containing 5A 11 124115362-124147721 Predicted intracellular proteins Evidence at protein level HPA037813, HPA037814, HPA061500 Uncertain Enhanced Nucleus Renal cancer:1.55e-5 (favourable) Expressed in all Expressed in all gallbladder: 48.7 Cell line enhanced CAPAN-2: 52.4;HEL: 39.5;HUVEC TERT2: 32.9;RPTEC TERT1: 32.4 +DNAJC4 HSPF2, MCG18 ENSG00000110011 DnaJ heat shock protein family (Hsp40) member C4 11 64230278-64234286 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011947 Uncertain Colorectal cancer:3.12e-4 (unfavourable), Renal cancer:6.21e-4 (favourable) Expressed in all Expressed in all testis: 136.6 Expressed in all +SIAE CSE-C, LSE, MGC87009, YSG2 ENSG00000110013 Sialic acid acetylesterase 11 124633113-124695707 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038052, HPA038053 Approved Renal cancer:4.42e-11 (favourable), Endometrial cancer:4.66e-5 (favourable) Expressed in all Expressed in all rectum: 114.5 Mixed +SNX15 ENSG00000110025 Sorting nexin 15 11 65027408-65040572 Predicted intracellular proteins Evidence at protein level HPA038955 Approved Supported Nucleoli
Cytosol Not detected Expressed in all cerebral cortex: 24.7 Expressed in all +LPXN LDPL ENSG00000110031 Leupaxin 11 58526871-58578220 Predicted intracellular proteins Evidence at protein level HPA043741, CAB046478, HPA061441 Supported Enhanced Nuclear speckles
Focal adhesion sites
Cytosol Endometrial cancer:8.81e-4 (favourable) Expressed in all Expressed in all tonsil: 107.2 Cell line enhanced HMC-1: 289.6;Karpas-707: 204.9 +DTX4 KIAA0937, RNF155 ENSG00000110042 Deltex E3 ubiquitin ligase 4 11 59171430-59208587 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056760, HPA059294 Uncertain Approved Approved Vesicles Thyroid cancer:5.81e-4 (favourable), Renal cancer:8.94e-4 (unfavourable) Expressed in all Mixed lung: 27.3 Cell line enhanced BEWO: 63.2;RT4: 80.7 +ATG2A KIAA0404 ENSG00000110046 Autophagy related 2A 11 64894546-64917248 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038715 Uncertain Approved Nucleus
Vesicles
Cytosol Renal cancer:4.79e-5 (favourable) Expressed in all Expressed in all bone marrow: 39.0 Expressed in all +EHD1 FLJ42622, FLJ44618, H-PAST, HPAST1, PAST1 ENSG00000110047 EH domain containing 1 11 64851642-64888296 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049890, HPA049986, HPA066751, HPA067747 Approved Supported Plasma membrane Liver cancer:2.81e-5 (unfavourable) Expressed in all Expressed in all testis: 152.8 Expressed in all +OSBP OSBP1 ENSG00000110048 Oxysterol binding protein 11 59574398-59616144 Predicted intracellular proteins Evidence at protein level HPA039227, HPA043625 Enhanced Enhanced Nucleus
Golgi apparatus
Cytosol Renal cancer:3.08e-7 (favourable), Colorectal cancer:2.08e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 73.9 Expressed in all +UNC93B1 UNC93 ENSG00000110057 Unc-93 homolog B1 (C. elegans) 11 67991104-68004982 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA038716, HPA038717, HPA042803 Approved Approved Nucleoplasm Pancreatic cancer:1.73e-4 (unfavourable), Renal cancer:7.38e-4 (unfavourable) Expressed in all Mixed spleen: 54.4 Cell line enhanced CAPAN-2: 111.1;RPMI-8226: 250.7 +PUS3 FKSG32 ENSG00000110060 Pseudouridylate synthase 3 11 125893485-125903221 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038040, HPA063802 Uncertain Approved Nucleus
Cytosol Head and neck cancer:8.10e-4 (unfavourable) Expressed in all Expressed in all liver: 16.9 Expressed in all +DCPS HINT-5, HSL1, HSPC015 ENSG00000110063 Decapping enzyme, scavenger 11 126303752-126345749 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039632, HPA058597 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all lymph node: 24.5 Expressed in all +KMT5B CGI-85, SUV420H1 ENSG00000110066 Lysine methyltransferase 5B 11 68154863-68213828 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063648 Supported Nucleus Urothelial cancer:9.30e-4 (favourable) Expressed in all Expressed in all thyroid gland: 52.2 Expressed in all +FOXRED1 H17 ENSG00000110074 FAD dependent oxidoreductase domain containing 1 11 126269055-126278131 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039620, HPA046192 Uncertain Supported Mitochondria Renal cancer:2.01e-6 (favourable), Breast cancer:7.36e-4 (unfavourable) Expressed in all Expressed in all liver: 19.1 Expressed in all +PPP6R3 C11orf23, DKFZp781E17107, DKFZp781E2374, DKFZp781O2362, FLJ11058, FLJ43065, KIAA1558, MGC125711, MGC125712, PP6R3, SAP190, SAPL, SAPLa, SAPS3 ENSG00000110075 Protein phosphatase 6 regulatory subunit 3 11 68460731-68615334 Predicted intracellular proteins Evidence at protein level CAB017183, HPA038467, HPA038468 Enhanced Enhanced Nucleoplasm
Plasma membrane
Cytosol Testis cancer:8.23e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 93.8 Expressed in all +NRXN2 ENSG00000110076 Neurexin 2 11 64606174-64723188 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 8 cerebral cortex: 142.6 testis: 17.0 Cell line enhanced REH: 43.5;SCLC-21H: 27.0;U-2 OS: 27.6;U-87 MG: 18.3 +MS4A6A CD20L3, MS4A6 ENSG00000110077 Membrane spanning 4-domains A6A 11 60172014-60184666 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA011391 Approved Cervical cancer:6.33e-4 (favourable) Expressed in all Expressed in all lymph node: 113.5 Cell line enriched 6 THP-1: 32.2 +MS4A4A CD20L1, MS4A4, MS4A7 ENSG00000110079 Membrane spanning 4-domains A4A 11 60280541-60308972 Predicted membrane proteins Evidence at transcript level HPA029323 Approved Expressed in all Tissue enhanced placenta: 102.2 adipose tissue: 63.4 Cell line enriched 24 K-562: 118.6 +ST3GAL4 CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, STZ ENSG00000110080 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 11 126355640-126440344 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA049827 Approved Expressed in all Mixed epididymis: 106.8 Expressed in all +CPT1A CPT1, CPT1-L, L-CPT1 ENSG00000110090 Carnitine palmitoyltransferase 1A 11 68754620-68844410 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008835 Enhanced Supported Mitochondria Renal cancer:2.67e-7 (favourable), Breast cancer:3.84e-4 (unfavourable) Expressed in all Expressed in all small intestine: 78.9 Mixed +CCND1 BCL1, D11S287E, PRAD1, U21B31 ENSG00000110092 Cyclin D1 11 69641087-69654474 Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB000024, HPA027802 Uncertain Supported Nucleoplasm Pancreatic cancer:1.96e-4 (unfavourable), Head and neck cancer:5.51e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 340.4 skin: 140.5 Cell line enhanced WM-115: 1198.2 +CCDC86 MGC2574 ENSG00000110104 Coiled-coil domain containing 86 11 60842071-60851081 Predicted intracellular proteins Evidence at protein level HPA041117, HPA041540 Enhanced Enhanced Nucleus
Nucleoli Head and neck cancer:7.36e-5 (unfavourable), Liver cancer:1.71e-4 (unfavourable) Expressed in all Tissue enriched 11 parathyroid gland: 618.3 testis: 58.1 Expressed in all +PRPF19 hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4 ENSG00000110107 Pre-mRNA processing factor 19 11 60890730-60906588 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012448, HPA038051, HPA059070 Supported Enhanced Nuclear speckles Liver cancer:4.11e-8 (unfavourable) Expressed in all Expressed in all cerebral cortex: 128.9 Expressed in all +TMEM109 MGC5508 ENSG00000110108 Transmembrane protein 109 11 60913874-60923443 Predicted membrane proteins, Transporters Evidence at protein level HPA011785 Approved Approved Nuclear membrane
Cytosol Urothelial cancer:2.68e-4 (unfavourable) Expressed in all Expressed in all endometrium: 94.7 Expressed in all +CCKBR ENSG00000110148 Cholecystokinin B receptor 11 6259736-6272127 Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Tissue enriched Group enriched 13 cerebral cortex: 13.6;pancreas: 5.4;stomach: 16.4 prostate: 0.9 Cell line enriched 8 NTERA-2: 69.8 +HPX ENSG00000110169 Hemopexin 11 6431049-6442617 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB016725 Supported Liver cancer:2.26e-4 (favourable) Tissue enriched Tissue enriched 506 liver: 2617.9 breast: 5.1 Cell line enriched 6 Hep G2: 13.9 +TRIM3 BERP, HAC1, RNF22, RNF97 ENSG00000110171 Tripartite motif containing 3 11 6448613-6474459 Predicted intracellular proteins Evidence at protein level HPA043396, HPA048233 Uncertain Approved Mitochondria Renal cancer:1.07e-5 (unfavourable), Pancreatic cancer:5.49e-5 (favourable), Endometrial cancer:2.20e-4 (favourable) Expressed in all Mixed duodenum: 17.8 Cell line enhanced SK-BR-3: 40.6 +CHORDC1 CHP-1, CHP1 ENSG00000110172 Cysteine and histidine rich domain containing 1 11 90201160-90223364 Predicted intracellular proteins Evidence at protein level HPA041040 Approved Supported Cytosol Liver cancer:4.93e-7 (unfavourable), Renal cancer:1.88e-4 (unfavourable) Expressed in all Expressed in all placenta: 31.4 Expressed in all +FOLR1 FOLR ENSG00000110195 Folate receptor 1 11 72189558-72196323 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA077030 Approved Nuclear membrane Liver cancer:2.50e-4 (unfavourable) Tissue enhanced Tissue enhanced cervix, uterine: 166.6;fallopian tube: 275.8;lung: 267.5 kidney: 152.7 Group enriched 6 HeLa: 298.2;RPTEC TERT1: 350.8 +ANAPC15 APC15, C11orf51, DKFZP564M082, HSPC020 ENSG00000110200 Anaphase promoting complex subunit 15 11 72106378-72112780 Predicted intracellular proteins Evidence at protein level HPA036596 Approved Approved Nucleoplasm
Vesicles Ovarian cancer:2.55e-4 (favourable), Liver cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all testis: 77.6 Expressed in all +FOLR3 FR-G ENSG00000110203 Folate receptor 3 11 72114869-72139892 Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced bone marrow: 56.7 appendix: 12.4 Group enriched 5 hTERT-HME1: 55.6;U-2197: 60.1 +PANX1 MRS1, PX1, UNQ2529 ENSG00000110218 Pannexin 1 11 94128928-94181972 Predicted membrane proteins, Transporters Evidence at protein level HPA016930 Uncertain Enhanced Plasma membrane Renal cancer:1.49e-7 (unfavourable), Lung cancer:7.09e-5 (unfavourable), Endometrial cancer:1.13e-4 (unfavourable) Expressed in all Expressed in all testis: 19.5 Expressed in all +ARHGEF17 KIAA0337, p164-RhoGEF, TEM4 ENSG00000110237 Rho guanine nucleotide exchange factor 17 11 73308289-73369091 Predicted intracellular proteins Evidence at protein level HPA007991 Uncertain Approved Cytosol Colorectal cancer:8.27e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 37.6 Mixed +APOA5 APOA-V, RAP3 ENSG00000110243 Apolipoprotein A5 11 116789367-116792420 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 273 liver: 259.2 testis: 0.9 Cell line enriched 54 Hep G2: 40.9 +APOA4 ENSG00000110244 Apolipoprotein A4 11 116820700-116823306 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001352, HPA002549, CAB068250, CAB068251, CAB068252 Enhanced Approved Vesicles Tissue enriched Group enriched 126 duodenum: 2211.8;small intestine: 3441.1 liver: 22.3 Cell line enhanced BEWO: 7.4;CACO-2: 6.6;Hep G2: 5.1;NB-4: 4.6;RPMI-8226: 8.2;SH-SY5Y: 11.1 +APOC3 ENSG00000110245 Apolipoprotein C3 11 116829706-116833072 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA065365 Approved Nucleoplasm
Nucleoli
Cell Junctions Renal cancer:6.87e-5 (unfavourable), Liver cancer:3.77e-4 (favourable) Tissue enriched Tissue enriched 7 liver: 8677.3 small intestine: 1178.4 Group enriched 17 CACO-2: 85.2;Hep G2: 190.9 +CEP164 KIAA1052, NPHP15 ENSG00000110274 Centrosomal protein 164 11 117314557-117413268 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037605, HPA037606, HPA061504 Uncertain Enhanced Nucleoplasm
Centrosome Liver cancer:2.40e-5 (unfavourable), Renal cancer:2.89e-5 (unfavourable), Pancreatic cancer:5.93e-4 (favourable) Expressed in all Mixed testis: 44.6 Expressed in all +RNF141 ZFP26, ZNF230 ENSG00000110315 Ring finger protein 141 11 10511678-10541230 Predicted intracellular proteins Evidence at protein level HPA018133 Approved Approved Nucleoplasm
Microtubules Pancreatic cancer:1.14e-4 (unfavourable), Renal cancer:2.60e-4 (favourable) Expressed in all Expressed in all testis: 130.2 Expressed in all +CEP126 KIAA1377 ENSG00000110318 Centrosomal protein 126 11 101915015-102001058 Predicted intracellular proteins Evidence at protein level HPA038381, HPA038399 Uncertain Nucleoplasm
Cytosol Renal cancer:5.00e-4 (unfavourable) Mixed Tissue enhanced testis: 17.6 fallopian tube: 12.9 Cell line enhanced EFO-21: 5.9 +EIF4G2 DAP5, NAT1, p97 ENSG00000110321 Eukaryotic translation initiation factor 4 gamma 2 11 10797050-10809110 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005163, HPA006773, HPA016965 Approved Enhanced Cytosol Liver cancer:6.18e-5 (unfavourable), Renal cancer:1.67e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 686.8 Expressed in all +IL10RA CD210, CD210a, CDW210A, HIL-10R, IL10R ENSG00000110324 Interleukin 10 receptor subunit alpha 11 117986348-118003037 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Renal cancer:1.45e-5 (unfavourable), Head and neck cancer:4.47e-4 (favourable) Expressed in all Tissue enhanced spleen: 86.2 lymph node: 56.0 Cell line enhanced Daudi: 21.3;HDLM-2: 69.7;Karpas-707: 19.5;RPMI-8226: 23.7 +GALNT18 GalNAc-T18, GALNT15, GALNTL4, MGC71806 ENSG00000110328 Polypeptide N-acetylgalactosaminyltransferase 18 11 11270876-11622005 Enzymes, Predicted membrane proteins Evidence at protein level HPA012955 Approved Approved Mitochondria Endometrial cancer:1.29e-4 (unfavourable) Expressed in all Tissue enhanced thyroid gland: 59.3 lung: 43.2 Cell line enhanced A-431: 36.5;HaCaT: 46.1;PC-3: 33.7;SK-BR-3: 35.3;U-87 MG: 32.9 +BIRC2 API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48 ENSG00000110330 Baculoviral IAP repeat containing 2 11 102347211-102378670 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA005513, CAB020661 Supported Supported Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all Expressed in all testis: 45.8 Mixed +UBE4A E4, KIAA0126, UBOX2, UFD2 ENSG00000110344 Ubiquitination factor E4A 11 118359585-118399211 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055035, HPA064010 Approved Supported Nuclear speckles Expressed in all Expressed in all parathyroid gland: 43.7 Expressed in all +DDX6 HLR2, RCK ENSG00000110367 DEAD-box helicase 6 11 118747766-118791149 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004668, HPA024201, HPA026644 Approved Supported Cytosol
Cytoplasmic bodies Liver cancer:6.56e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 65.6 Expressed in all +UPK2 MGC138598, UP2, UPII ENSG00000110375 Uroplakin 2 11 118925164-118958559 Predicted membrane proteins, Transporters Evidence at protein level HPA043312, HPA061106 Enhanced Renal cancer:7.30e-7 (unfavourable), Lung cancer:9.57e-4 (unfavourable) Tissue enriched Tissue enriched 44 urinary bladder: 68.5 adipose tissue: 1.5 Cell line enhanced BEWO: 25.9;MCF7: 113.9;RT4: 131.8 +CBL c-Cbl, CBL2, RNF55 ENSG00000110395 Cbl proto-oncogene 11 119206276-119313926 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004350, HPA027956 Enhanced Supported Cytosol Expressed in all Mixed testis: 33.9 Expressed in all +NECTIN1 CD111, CLPED1, ED4, HIgR, HVEC, OFC7, PRR, PRR1, PVRL1, PVRR1, SK-12 ENSG00000110400 Nectin cell adhesion molecule 1 11 119623408-119729084 CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB016135, HPA026846 Approved Expressed in all Tissue enhanced esophagus: 108.6;skin: 161.7 cerebral cortex: 50.3 Cell line enhanced HaCaT: 203.5 +HIPK3 DYRK6, FIST3, PKY, YAK1 ENSG00000110422 Homeodomain interacting protein kinase 3 11 33256672-33357023 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028069 Approved Supported Nuclear bodies
Cytosol Expressed in all Expressed in all parathyroid gland: 126.8 Expressed in all +KIAA1549L C11orf41, C11orf69, G2, MGC34830 ENSG00000110427 KIAA1549 like 11 33542072-33674102 Predicted membrane proteins Evidence at protein level HPA051594 Approved Nucleoplasm Mixed Group enriched 41 cerebral cortex: 34.9;parathyroid gland: 146.2 skin: 2.2 Cell line enhanced TIME: 43.4;U-138 MG: 64.2;WM-115: 44.5 +FBXO3 FBA, FBX3 ENSG00000110429 F-box protein 3 11 33740939-33774543 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002467 Approved Nucleoplasm
Cytosol Renal cancer:2.46e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 89.6 Expressed in all +PDHX DLDBP, E3BP, OPDX, PDX1, proX ENSG00000110435 Pyruvate dehydrogenase complex component X 11 34915829-35020591 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038484, HPA038485 Enhanced Approved Nucleus
Plasma membrane
Mitochondria Renal cancer:1.83e-5 (favourable) Expressed in all Expressed in all heart muscle: 53.3 Expressed in all +SLC1A2 EAAT2, GLT-1 ENSG00000110436 Solute carrier family 1 member 2 11 35251206-35420063 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB002574, HPA009172 Enhanced Tissue enriched Tissue enriched 30 cerebral cortex: 365.8 liver: 12.2 Cell line enhanced fHDF/TERT166: 1.5;NTERA-2: 2.4;SCLC-21H: 1.5 +COMMD9 FLJ31106, HSPC166 ENSG00000110442 COMM domain containing 9 11 36269284-36289449 Predicted intracellular proteins Evidence at protein level HPA009142 Uncertain Approved Nucleus
Golgi apparatus
Cytosol Ovarian cancer:8.54e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 48.3 Expressed in all +SLC15A3 hPTR3, PHT2 ENSG00000110446 Solute carrier family 15 member 3 11 60937084-60952530 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA047880, HPA057642 Approved Supported Vesicles Cervical cancer:4.07e-5 (favourable) Expressed in all Expressed in all lung: 102.2 Cell line enhanced BJ hTERT+ SV40 Large T+: 91.0;BJ hTERT+ SV40 Large T+ RasG12V: 114.5;HHSteC: 47.3 +CD5 LEU1, T1 ENSG00000110448 CD5 molecule 11 61102395-61127852 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB015392, CAB020308, HPA043416, HPA060839 Enhanced Head and neck cancer:7.41e-6 (favourable), Renal cancer:8.94e-5 (unfavourable), Endometrial cancer:9.00e-5 (favourable), Cervical cancer:9.16e-5 (favourable), Melanoma:3.93e-4 (favourable), Breast cancer:4.05e-4 (favourable) Mixed Tissue enhanced appendix: 29.8;lymph node: 43.0 tonsil: 20.2 Cell line enriched 71 MOLT-4: 56.4 +ACCS ACS, PHACS ENSG00000110455 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) 11 44065925-44084222 Predicted intracellular proteins Evidence at protein level HPA018873, HPA021654 Approved Approved Golgi apparatus Pancreatic cancer:4.25e-4 (favourable) Expressed in all Mixed spleen: 18.8 Mixed +SCGB2A2 MGB1, MGC71974, UGB2 ENSG00000110484 Secretoglobin family 2A member 2 11 62270155-62273156 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB026270 Supported Endometrial cancer:9.57e-8 (favourable) Tissue enriched Tissue enriched 7 breast: 3687.7 cervix, uterine: 507.6 Cell line enriched 95 SK-BR-3: 13.3 +MDK FLJ27379, MK, NEGF2 ENSG00000110492 Midkine (neurite growth-promoting factor 2) 11 46380756-46383837 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB010055, HPA057126 Uncertain Approved Vesicles Renal cancer:3.06e-6 (unfavourable), Glioma:9.54e-4 (unfavourable) Expressed in all Expressed in all ovary: 524.3 Cell line enhanced NTERA-2: 890.9;REH: 1226.8;SH-SY5Y: 1163.1 +AMBRA1 DCAF3, FLJ20294, KIAA1736, WDR94 ENSG00000110497 Autophagy and beclin 1 regulator 1 11 46396414-46594125 Predicted intracellular proteins Evidence at protein level CAB017825, HPA038535 Approved Approved Vesicles
Mitochondria Renal cancer:1.61e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.0 Expressed in all +MADD DENN, KIAA0358, RAB3GEP ENSG00000110514 MAP kinase activating death domain 11 47269161-47330031 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038568 Uncertain Supported Plasma membrane
Cytosol Pancreatic cancer:5.69e-5 (favourable), Endometrial cancer:6.62e-5 (favourable), Urothelial cancer:8.25e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 103.9 Expressed in all +PTPMT1 DUSP23, MOSP, PLIP ENSG00000110536 Protein tyrosine phosphatase, mitochondrial 1 11 47565430-47573461 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040348, HPA043932 Approved Supported Mitochondria Liver cancer:3.04e-5 (unfavourable) Expressed in all Expressed in all testis: 92.8 Expressed in all +NAA40 FLJ13848, NAT11 ENSG00000110583 N(alpha)-acetyltransferase 40, NatD catalytic subunit 11 63938959-63957328 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037816 Uncertain Approved Nuclear bodies Liver cancer:1.43e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 27.1 Expressed in all +CARS CARS1 ENSG00000110619 Cysteinyl-tRNA synthetase 11 3000922-3057613 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737 Enhanced Enhanced Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:5.16e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 28.2 Mixed +SLC22A18 BWR1A, BWSCR1A, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5 ENSG00000110628 Solute carrier family 22 member 18 11 2899721-2925246 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA067812, HPA071461 Enhanced Expressed in all Tissue enhanced duodenum: 43.2;small intestine: 31.7 colon: 10.3 Cell line enhanced CAPAN-2: 28.3;Karpas-707: 21.3 +CD81 TAPA-1, TAPA1, TSPAN28 ENSG00000110651 CD81 molecule 11 2376177-2397419 CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB002507, HPA007234 Supported Supported Plasma membrane Glioma:5.12e-5 (unfavourable), Pancreatic cancer:3.86e-4 (favourable), Colorectal cancer:7.56e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 2273.0 Cell line enhanced ASC diff: 2031.3 +SLC35F2 FLJ13018 ENSG00000110660 Solute carrier family 35 member F2 11 107790991-107928293 Predicted membrane proteins, Transporters Evidence at protein level HPA048185, HPA050695 Uncertain Approved Mitochondria Pancreatic cancer:5.92e-6 (unfavourable), Lung cancer:4.03e-4 (unfavourable), Glioma:7.31e-4 (favourable) Expressed in all Mixed prostate: 33.8 Cell line enhanced PC-3: 166.4 +C11orf21 ENSG00000110665 Chromosome 11 open reading frame 21 11 2295645-2303049 Predicted intracellular proteins Evidence at transcript level HPA037607 Approved Mixed Tissue enhanced bone marrow: 32.4;spleen: 17.6 lymph node: 15.9 Cell line enhanced HEL: 45.5;HL-60: 15.4;NB-4: 11.2;U-937: 16.8 +ELMOD1 DKFZp547C176 ENSG00000110675 ELMO domain containing 1 11 107591091-107666779 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038434, HPA038435 Supported Nucleoplasm
Cytosol Tissue enriched Group enriched 15 cerebral cortex: 71.3;skin: 36.7 adrenal gland,fallopian tube: 3.5 Cell line enhanced HUVEC TERT2: 12.8;RH-30: 33.5 +CALCA CALC1 ENSG00000110680 Calcitonin related polypeptide alpha 11 14966668-14972354 Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA059886 Supported Endometrial cancer:4.49e-5 (unfavourable) Tissue enriched Group enriched 78 parathyroid gland: 849.6;thyroid gland: 183.4 kidney: 6.6 Not detected +SOX6 ENSG00000110693 SRY-box 6 11 15966449-16739591 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001923, HPA003908 Enhanced Approved Nucleoplasm Renal cancer:6.47e-12 (favourable) Mixed Tissue enhanced testis: 25.9 bone marrow: 16.5 Cell line enhanced WM-115: 20.4 +C11orf58 SMAP ENSG00000110696 Chromosome 11 open reading frame 58 11 16613132-16756881 Predicted intracellular proteins Evidence at protein level HPA036591, HPA076406 Uncertain Approved Nucleoplasm
Endoplasmic reticulum Liver cancer:5.84e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 217.7 Expressed in all +PITPNM1 DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1 ENSG00000110697 Phosphatidylinositol transfer protein membrane associated 1 11 67491768-67506263 Predicted intracellular proteins Evidence at protein level HPA060227, HPA062757 Approved Enhanced Microtubule organizing center
Cytosol
Cytoplasmic bodies Expressed in all Expressed in all fallopian tube: 37.0 Expressed in all +RPS13 S13 ENSG00000110700 Ribosomal protein S13 11 17074389-17077787 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA005985 Uncertain Approved Endoplasmic reticulum Renal cancer:1.54e-4 (unfavourable) Expressed in all Expressed in all ovary: 2365.9 Expressed in all +AIP ARA9, FKBP16, XAP2 ENSG00000110711 Aryl hydrocarbon receptor interacting protein 11 67483041-67491103 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033674, HPA050217, CAB069477 Approved Supported Cytosol Colorectal cancer:1.93e-4 (unfavourable) Expressed in all Expressed in all lymph node: 100.6 Expressed in all +NUP98 NUP96 ENSG00000110713 Nucleoporin 98 11 3671083-3797792 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA074810 Supported Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 150.7 Expressed in all +NDUFS8 CI-23k, TYKY ENSG00000110717 NADH:ubiquinone oxidoreductase core subunit S8 11 68030617-68036644 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018524 Approved Supported Mitochondria Renal cancer:3.27e-8 (favourable) Expressed in all Expressed in all adrenal gland: 152.6 Expressed in all +TCIRG1 a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7 ENSG00000110719 T-cell immune regulator 1, ATPase H+ transporting V0 subunit a3 11 68039016-68050895 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038742 Approved Approved Mitochondria Renal cancer:1.50e-11 (unfavourable), Urothelial cancer:9.45e-6 (favourable) Expressed in all Expressed in all spleen: 82.0 Mixed +CHKA CHK, CKI ENSG00000110721 Choline kinase alpha 11 68052859-68121444 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024153, CAB072803 Approved Approved Endoplasmic reticulum Liver cancer:7.75e-4 (unfavourable) Expressed in all Expressed in all testis: 136.1 Expressed in all +EXPH5 SLAC2-B ENSG00000110723 Exophilin 5 11 108505431-108593738 Disease related genes, Predicted intracellular proteins Evidence at protein level Endometrial cancer:3.42e-6 (favourable), Head and neck cancer:1.46e-4 (favourable), Renal cancer:2.43e-4 (favourable), Lung cancer:5.12e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 16.1;skin: 31.3 esophagus: 8.2 Cell line enhanced hTERT-HME1: 8.7;RT4: 16.3 +HPS5 AIBP63, BLOC2S2, RU2 ENSG00000110756 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 11 18278668-18322198 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:2.05e-4 (unfavourable) Expressed in all Expressed in all testis: 39.9 Expressed in all +GTF2H1 BTF2, P62, TFIIH ENSG00000110768 General transcription factor IIH subunit 1 11 18322295-18367044 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB004637, HPA046660 Enhanced Enhanced Nucleoplasm Liver cancer:5.98e-9 (unfavourable) Expressed in all Expressed in all testis: 60.0 Expressed in all +POU2AF1 BOB1, OBF1 ENSG00000110777 POU class 2 associating factor 1 11 111352252-111455630 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011193 Enhanced Cervical cancer:1.63e-4 (favourable), Breast cancer:1.68e-4 (favourable), Head and neck cancer:3.59e-4 (favourable) Mixed Tissue enhanced lymph node: 101.7;tonsil: 93.7 appendix: 55.5 Cell line enhanced Daudi: 190.2;Karpas-707: 212.1;U-266/70: 217.7;U-698: 374.3 +PTPN5 PTPSTEP, STEP, STEP61 ENSG00000110786 Protein tyrosine phosphatase, non-receptor type 5 11 18727928-18792721 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031014, HPA072091 Supported Approved Endoplasmic reticulum Group enriched Tissue enriched 15 cerebral cortex: 58.8 testis: 3.8 Cell line enhanced NTERA-2: 1.7 +VWF F8VWF ENSG00000110799 Von Willebrand factor 12 5948874-6124770 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB001694, HPA001815, HPA002082, CAB072874, CAB072875 Supported Stomach cancer:2.31e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 155.1 lung: 115.9 Cell line enriched 57 HUVEC TERT2: 468.1 +PSMD9 p27, Rpn4 ENSG00000110801 Proteasome 26S subunit, non-ATPase 9 12 121888731-121918297 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040512, HPA044220 Enhanced Supported Plasma membrane
Cytosol Liver cancer:1.32e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 17.8 Expressed in all +P3H3 GRCB, HSU47926, LEPREL2 ENSG00000110811 Prolyl 3-hydroxylase 3 12 6828410-6839851 Enzymes, Predicted secreted proteins Evidence at protein level HPA043695 Approved Approved Nucleoli
Plasma membrane
Cytosol Renal cancer:1.64e-4 (unfavourable), Pancreatic cancer:4.91e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 11.7 endometrium: 6.2 Cell line enhanced BJ: 33.3 +PPFIBP1 hSGT2, hSgt2p, L2, SGT2 ENSG00000110841 PPFIA binding protein 1 12 27523431-27695564 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001924 Uncertain Approved Plasma membrane
Cytosol Renal cancer:5.11e-7 (favourable), Pancreatic cancer:2.56e-4 (unfavourable), Lung cancer:5.11e-4 (unfavourable), Endometrial cancer:6.29e-4 (unfavourable) Expressed in all Expressed in all ovary: 106.4 Mixed +PRPF40B HYPC ENSG00000110844 Pre-mRNA processing factor 40 homolog B 12 49568218-49644666 Predicted intracellular proteins Evidence at protein level HPA038426, HPA038599 Enhanced Approved Nucleoplasm
Nuclear bodies
Aggresome
Cytosol Mixed Mixed testis: 39.2 Expressed in all +CD69 CLEC2C ENSG00000110848 CD69 molecule 12 9752486-9760901 CD markers, Predicted membrane proteins Evidence at protein level CAB002503, HPA050525 Enhanced Breast cancer:3.31e-5 (favourable), Renal cancer:7.87e-5 (unfavourable) Mixed Tissue enhanced bone marrow: 105.9;lymph node: 109.1 appendix: 64.1 Cell line enhanced HL-60: 23.7;K-562: 52.0;U-937: 76.0 +PRDM4 PFM1 ENSG00000110851 PR/SET domain 4 12 107732866-107761272 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024322, HPA067437 Approved Supported Nucleoplasm Renal cancer:3.15e-7 (favourable), Liver cancer:1.86e-4 (unfavourable), Melanoma:7.66e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 90.0 Expressed in all +CLEC2B AICL, CLECSF2, HP10085 ENSG00000110852 C-type lectin domain family 2 member B 12 9852984-9870136 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008194 Approved Renal cancer:5.64e-13 (unfavourable) Expressed in all Mixed skin: 87.2 Cell line enhanced ASC TERT1: 56.7;U-937: 154.3 +COQ5 MGC4767 ENSG00000110871 Coenzyme Q5, methyltransferase 12 120503274-120534434 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049487 Approved Approved Nucleoli
Mitochondria Expressed in all Expressed in all thyroid gland: 42.1 Expressed in all +SELPLG CD162, PSGL-1 ENSG00000110876 Selectin P ligand 12 108622277-108633959 Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002431 Enhanced Cervical cancer:1.46e-4 (favourable), Thyroid cancer:2.74e-4 (favourable), Melanoma:2.92e-4 (favourable), Renal cancer:5.86e-4 (unfavourable), Head and neck cancer:6.94e-4 (favourable) Expressed in all Mixed spleen: 85.3 Cell line enhanced HDLM-2: 137.1;HMC-1: 120.1;Karpas-707: 155.1;RPMI-8226: 215.5;U-266/70: 266.2;U-266/84: 163.2 +CORO1C coronin-3, HCRNN4 ENSG00000110880 Coronin 1C 12 108645109-108731596 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041737 Approved Liver cancer:5.59e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 208.8 Expressed in all +ASIC1 ACCN2, BNaC2, hBNaC2 ENSG00000110881 Acid sensing ion channel subunit 1 12 50057548-50083611 FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA058870 Approved Golgi apparatus
Plasma membrane Tissue enhanced Tissue enriched 10 cerebral cortex: 56.8 parathyroid gland: 5.7 Cell line enhanced SH-SY5Y: 30.8 +DAO DAMOX ENSG00000110887 D-amino acid oxidase 12 108858932-108901043 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038653, HPA038654 Enhanced Renal cancer:4.11e-4 (favourable) Tissue enriched Group enriched 36 kidney: 89.8;liver: 74.1 rectum: 2.2 Not detected +CAPRIN2 C1QDC1, caprin-2, EEG1, FLJ11391, FLJ22569, RNG140 ENSG00000110888 Caprin family member 2 12 30709552-30754951 Predicted intracellular proteins Evidence at protein level HPA039746 Supported Supported Nucleus
Centrosome
Cytosol Renal cancer:3.50e-5 (unfavourable), Urothelial cancer:8.36e-4 (favourable) Expressed in all Mixed testis: 32.8 Mixed +TSPAN11 ENSG00000110900 Tetraspanin 11 12 30926428-30996599 Predicted membrane proteins Evidence at protein level HPA066789 Approved Vesicles Lung cancer:3.43e-4 (favourable), Head and neck cancer:5.28e-4 (favourable) Mixed Mixed cerebral cortex: 17.9 Group enriched 5 AF22: 26.8;HSkMC: 19.0;NTERA-2: 21.6;SCLC-21H: 12.2;SH-SY5Y: 21.8 +KCTD10 BTBD28, MSTP028 ENSG00000110906 Potassium channel tetramerization domain containing 10 12 109448656-109477544 Predicted intracellular proteins Evidence at protein level HPA014273 Approved Supported Nucleoplasm
Cytosol Liver cancer:5.32e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 79.7 Expressed in all +SLC11A2 DCT1, DMT1, NRAMP2 ENSG00000110911 Solute carrier family 11 member 2 12 50979401-51028566 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA032139, HPA032140 Uncertain Supported Mitochondria Lung cancer:3.07e-6 (favourable) Expressed in all Expressed in all thyroid gland: 75.1 Expressed in all +MLEC KIAA0152 ENSG00000110917 Malectin 12 120686869-120701864 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Endometrial cancer:9.60e-6 (favourable), Stomach cancer:8.77e-4 (favourable) Expressed in all Expressed in all thyroid gland: 162.3 Expressed in all +MVK LRBP, MK ENSG00000110921 Mevalonate kinase 12 109573255-109598117 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA016961 Approved Expressed in all Expressed in all testis: 31.6 Expressed in all +CSRNP2 C12ORF2, C12orf22, FAM130A1, PPP1R72, TAIP-12 ENSG00000110925 Cysteine and serine rich nuclear protein 2 12 51061205-51083664 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018503, HPA019914 Approved Approved Nuclear speckles Liver cancer:1.08e-4 (unfavourable), Urothelial cancer:2.78e-4 (favourable), Renal cancer:6.51e-4 (unfavourable) Expressed in all Expressed in all testis: 49.2 Expressed in all +CAMKK2 CAMKK, CAMKKB, KIAA0787, MGC15254 ENSG00000110931 Calcium/calmodulin dependent protein kinase kinase 2 12 121237691-121298308 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017389 Approved Supported Cytosol Expressed in all Expressed in all cerebral cortex: 102.8 Expressed in all +BIN2 BRAP-1 ENSG00000110934 Bridging integrator 2 12 51281038-51324668 Predicted intracellular proteins Evidence at protein level HPA038666, HPA038667 Enhanced Cervical cancer:1.33e-4 (favourable), Endometrial cancer:6.34e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 65.8 spleen: 53.1 Cell line enhanced HEL: 72.6;HMC-1: 116.1;NB-4: 87.3;THP-1: 78.0;U-937: 59.3 +IL23A IL-23, IL-23A, IL23P19, P19, SGRF ENSG00000110944 Interleukin 23 subunit alpha 12 56334174-56340410 FDA approved drug targets, Predicted secreted proteins Evidence at protein level HPA001554 Approved Approved Cytosol Expressed in all Tissue enhanced tonsil: 8.0 urinary bladder: 6.5 Cell line enhanced A-431: 13.0;CAPAN-2: 22.3;U-266/70: 31.8;U-266/84: 14.0 +ATP5B ATPSB ENSG00000110955 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 12 56638175-56646068 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001520, HPA001528, CAB017527 Enhanced Enhanced Mitochondria Renal cancer:1.43e-9 (favourable), Breast cancer:7.17e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 1254.0 Expressed in all +PTGES3 cPGES, p23, TEBP ENSG00000110958 Prostaglandin E synthase 3 12 56663341-56688408 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034319, HPA038672, HPA038673 Enhanced Supported Nucleoplasm
Cytosol Liver cancer:4.44e-6 (unfavourable), Breast cancer:2.15e-5 (unfavourable), Ovarian cancer:4.36e-4 (favourable) Expressed in all Expressed in all fallopian tube: 347.2 Expressed in all +SYT10 ENSG00000110975 Synaptotagmin 10 12 33374238-33439819 Predicted membrane proteins Evidence at transcript level HPA055426 Uncertain Approved Nucleoplasm
Vesicles Tissue enriched Tissue enhanced fallopian tube: 3.5 seminal vesicle: 1.1 Cell line enhanced AF22: 1.6;MCF7: 2.7;RT4: 1.1;SCLC-21H: 2.0 +BCL7A BCL7 ENSG00000110987 BCL tumor suppressor 7A 12 122019422-122062044 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019762 Approved Approved Nucleoplasm
Vesicles Renal cancer:1.54e-6 (favourable), Liver cancer:2.04e-4 (unfavourable), Colorectal cancer:6.81e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 13.8 Cell line enhanced Daudi: 37.3;U-698: 41.3 +RSRC2 FLJ11021 ENSG00000111011 Arginine and serine rich coiled-coil 2 12 122503458-122527000 Predicted intracellular proteins Evidence at protein level HPA040070, HPA048183 Uncertain Enhanced Nucleoli fibrillar center
Nuclear speckles
Cytosol Liver cancer:2.05e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 42.5 Expressed in all +CYP27B1 CYP1, P450c1, PDDR, VDD1 ENSG00000111012 Cytochrome P450 family 27 subfamily B member 1 12 57762334-57768986 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Thyroid cancer:6.79e-4 (unfavourable) Mixed Tissue enhanced kidney: 4.3;thyroid gland: 3.9 appendix: 1.2 Cell line enriched 8 RH-30: 47.8 +MYF6 bHLHc4, MRF4 ENSG00000111046 Myogenic factor 6 12 80707498-80709474 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Head and neck cancer:2.05e-4 (unfavourable) Group enriched Tissue enriched 15 skeletal muscle: 99.2 prostate: 6.4 Cell line enriched 20 LHCN-M2: 19.4 +MYF5 bHLHc2 ENSG00000111049 Myogenic factor 5 12 80716912-80719673 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041691 Supported Nucleoplasm Not detected Tissue enhanced skeletal muscle: 1.9 prostate: 0.4 Cell line enriched 19 LHCN-M2: 398.0 +LIN7A LIN-7A, MALS-1, TIP-33, VELI1 ENSG00000111052 Lin-7 homolog A, crumbs cell polarity complex component 12 80792520-80937925 Predicted intracellular proteins Evidence at protein level HPA071562 Approved Renal cancer:1.63e-11 (favourable) Tissue enhanced Mixed bone marrow: 17.8 Cell line enhanced ASC TERT1: 22.0;HAP1: 25.9;HDLM-2: 27.5;HL-60: 23.1 +KRT18 ENSG00000111057 Keratin 18 12 52948871-52952901 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB000008, CAB000030, HPA001605 Enhanced Enhanced Cytosol Pancreatic cancer:1.78e-4 (unfavourable), Lung cancer:5.06e-4 (unfavourable) Expressed in all Mixed placenta: 658.9 Cell line enhanced A549: 5013.4;CACO-2: 5077.2;CAPAN-2: 3861.0;MCF7: 6322.5 +ACSS3 FLJ21963 ENSG00000111058 Acyl-CoA synthetase short-chain family member 3 12 80936414-81261205 Enzymes, Predicted membrane proteins Evidence at protein level HPA039353, HPA047956, HPA061517 Approved Approved Mitochondria Renal cancer:0.00e+0 (favourable) Mixed Mixed parathyroid gland: 33.7 Cell line enhanced Hep G2: 28.4;RH-30: 18.1;SK-BR-3: 13.2 +TNS2 C1-TEN, KIAA1075, TENC1 ENSG00000111077 Tensin 2 12 53046969-53064372 Predicted intracellular proteins Evidence at protein level HPA034659 Approved Pancreatic cancer:1.72e-4 (favourable), Prostate cancer:9.32e-4 (favourable) Expressed in all Mixed adipose tissue: 114.4 Cell line enhanced ASC diff: 78.4;ASC TERT1: 54.1;HSkMC: 62.2 +GLI1 GLI ENSG00000111087 GLI family zinc finger 1 12 57460135-57472262 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009460, HPA065172, HPA068903 Uncertain Enhanced Nucleoplasm
Cytosol Tissue enhanced Tissue enhanced cervix, uterine: 15.1;endometrium: 15.1 gallbladder: 8.5 Cell line enhanced AN3-CA: 19.3;RH-30: 59.1 +PPM1H ARHCL1, FLJ13253, KIAA1157, NERPP-2C ENSG00000111110 Protein phosphatase, Mg2+/Mn2+ dependent 1H 12 62643982-62935037 Enzymes, Predicted intracellular proteins Evidence at protein level CAB020694, HPA044244, HPA058777 Approved Supported Nucleoplasm Renal cancer:2.72e-5 (favourable) Expressed in all Tissue enhanced parathyroid gland: 54.2 cerebral cortex: 23.0 Cell line enhanced CACO-2: 67.4;HMC-1: 56.0 +METAP2 MAP2, MNPEP, p67 ENSG00000111142 Methionyl aminopeptidase 2 12 95473520-95515839 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013025, HPA019095 Enhanced Supported Plasma membrane
Cytosol Liver cancer:4.51e-6 (unfavourable) Expressed in all Expressed in all seminal vesicle: 142.4 Expressed in all +LTA4H ENSG00000111144 Leukotriene A4 hydrolase 12 96000828-96043520 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008399, CAB015221, HPA017017 Supported Supported Nucleoplasm
Cytosol Lung cancer:8.96e-4 (favourable), Breast cancer:9.79e-4 (favourable) Expressed in all Expressed in all lung: 283.5 Expressed in all +ELK3 ERP, NET, SAP2 ENSG00000111145 ELK3, ETS transcription factor 12 96194382-96269835 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001600 Approved Supported Nucleoplasm
Mitochondria Ovarian cancer:4.93e-4 (unfavourable) Expressed in all Expressed in all endometrium: 58.4 Expressed in all +SLC6A12 BGT-1 ENSG00000111181 Solute carrier family 6 member 12 12 190077-214570 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA034973 Approved Approved Vesicles Renal cancer:2.70e-6 (favourable), Endometrial cancer:1.59e-4 (unfavourable) Tissue enhanced Tissue enhanced kidney: 29.5;liver: 43.6 cerebral cortex: 14.8 Group enriched 10 Hep G2: 4.9;RPTEC TERT1: 10.5 +WNT5B ENSG00000111186 Wnt family member 5B 12 1529891-1647243 Predicted secreted proteins Evidence at protein level HPA061991 Approved Vesicles Expressed in all Tissue enhanced prostate: 34.7 seminal vesicle: 27.9 Cell line enhanced BJ: 195.3;BJ hTERT+ SV40 Large T+: 154.0;BJ hTERT+ SV40 Large T+ RasG12V: 132.9;HBF TERT88: 139.5;hTEC/SVTERT24-B: 144.8;U-138 MG: 140.4 +MAGOHB FLJ10292, MGN2 ENSG00000111196 Mago homolog B, exon junction complex core component 12 10604190-10613623 Predicted intracellular proteins Evidence at protein level HPA043036, HPA047754 Uncertain Renal cancer:5.04e-8 (unfavourable), Ovarian cancer:5.56e-6 (favourable), Stomach cancer:6.50e-4 (favourable) Expressed in all Mixed epididymis: 14.3 Expressed in all +TRPV4 CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC ENSG00000111199 Transient receptor potential cation channel subfamily V member 4 12 109783085-109833401 Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA007150 Uncertain Renal cancer:4.12e-5 (favourable), Ovarian cancer:8.10e-4 (unfavourable) Expressed in all Mixed kidney: 11.8 Cell line enhanced BEWO: 9.1;HaCaT: 13.9 +ITFG2 MDS028 ENSG00000111203 Integrin alpha FG-GAP repeat containing 2 12 2812622-2859791 Predicted intracellular proteins Evidence at protein level HPA038664, HPA038665 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Cytokinetic bridge Expressed in all Expressed in all thyroid gland: 46.0 Expressed in all +FOXM1 FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident ENSG00000111206 Forkhead box M1 12 2857681-2877155 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017832 Uncertain Supported Nucleus
Nucleoli
Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.95e-6 (unfavourable), Pancreatic cancer:3.03e-5 (unfavourable), Lung cancer:2.92e-4 (unfavourable) Expressed in all Tissue enhanced testis: 39.6 bone marrow: 15.9 Expressed in all +PRR4 LPRP, PROL4 ENSG00000111215 Proline rich 4 (lacrimal) 12 10845849-11171613 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042133 Enhanced Uncertain Vesicles Mixed Tissue enriched 23 salivary gland: 1528.2 stomach: 65.1 Cell line enhanced HDLM-2: 1.4;HHSteC: 1.7 +PRMT8 HRMT1L3, HRMT1L4 ENSG00000111218 Protein arginine methyltransferase 8 12 3381349-3593973 Predicted intracellular proteins Evidence at protein level HPA039747, HPA069769 Enhanced Tissue enhanced Tissue enriched 8 cerebral cortex: 19.9 testis: 2.4 Cell line enriched 11 hTERT-HME1: 37.3 +PARP11 C12orf6 ENSG00000111224 Poly(ADP-ribose) polymerase family member 11 12 3791047-3873448 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026895 Uncertain Expressed in all Mixed testis: 17.6 Mixed +ARPC3 ARC21, p21-Arc ENSG00000111229 Actin related protein 2/3 complex subunit 3 12 110434825-110450422 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006550 Approved Uncertain Nucleoplasm Renal cancer:2.22e-11 (unfavourable), Pancreatic cancer:4.67e-4 (unfavourable) Expressed in all Expressed in all lymph node: 608.2 Expressed in all +GPN3 ATPBD1C, MGC14560 ENSG00000111231 GPN-loop GTPase 3 12 110452484-110469268 Predicted intracellular proteins Evidence at protein level HPA039764, HPA047793 Uncertain Approved Nuclear speckles
Cytosol Renal cancer:2.65e-6 (favourable), Liver cancer:3.98e-5 (unfavourable) Expressed in all Expressed in all testis: 74.2 Expressed in all +VPS29 DC15, DC7, PEP11 ENSG00000111237 VPS29, retromer complex component 12 110491097-110502117 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039748 Uncertain Supported Vesicles
Cytosol Liver cancer:2.79e-5 (unfavourable), Ovarian cancer:7.70e-4 (favourable) Expressed in all Expressed in all epididymis: 109.0 Expressed in all +FGF6 ENSG00000111241 Fibroblast growth factor 6 12 4428155-4445614 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Not detected Tissue enriched 8 skeletal muscle: 5.6 esophagus: 0.7 Group enriched 5 NTERA-2: 2.4;REH: 2.4 +MYL2 CMH10 ENSG00000111245 Myosin light chain 2 12 110910819-110920722 Candidate cardiovascular disease genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019763, HPA039262 Supported Uncertain Microtubules Head and neck cancer:2.60e-4 (unfavourable) Group enriched Group enriched 36 heart muscle: 16309.5;skeletal muscle: 9731.7 esophagus: 357.2 Group enriched 6 EFO-21: 3.7;HSkMC: 6.1;U-2 OS: 17.9 +RAD51AP1 PIR51 ENSG00000111247 RAD51 associated protein 1 12 4538798-4560048 Predicted intracellular proteins Evidence at protein level HPA051499 Approved Nucleus Renal cancer:4.44e-15 (unfavourable), Pancreatic cancer:1.22e-5 (unfavourable), Liver cancer:3.53e-4 (unfavourable), Endometrial cancer:9.42e-4 (unfavourable) Expressed in all Mixed testis: 11.4 Mixed +CUX2 CDP2, CUTL2, KIAA0293 ENSG00000111249 Cut like homeobox 2 12 111034024-111350554 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 12.2;liver: 9.6;prostate: 18.0 thyroid gland: 6.8 Cell line enhanced HBEC3-KT: 4.6;SCLC-21H: 7.5;SH-SY5Y: 14.5 +SH2B3 IDDM20, LNK ENSG00000111252 SH2B adaptor protein 3 12 111405948-111451623 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005483 Approved Approved Nucleoplasm Renal cancer:6.20e-4 (unfavourable) Expressed in all Expressed in all spleen: 51.1 Cell line enhanced hTEC/SVTERT24-B: 141.0;U-87 MG: 207.2;WM-115: 163.2 +AKAP3 AKAP110, CT82, FSP95, SOB1 ENSG00000111254 A-kinase anchoring protein 3 12 4615508-4649047 Predicted intracellular proteins Evidence at protein level HPA039765 Enhanced Tissue enriched Tissue enriched 46 testis: 179.9 fallopian tube: 3.9 Cell line enhanced NTERA-2: 4.0 +MANSC1 FLJ10298, LOH12CR3 ENSG00000111261 MANSC domain containing 1 12 12326056-12350541 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007955, HPA007956 Approved Approved Golgi apparatus
Vesicles Renal cancer:3.30e-5 (favourable) Expressed in all Mixed parathyroid gland: 24.7 Cell line enhanced HUVEC TERT2: 42.6 +KCNA1 AEMK, HUK1, Kv1.1, MBK1, RBK1 ENSG00000111262 Potassium voltage-gated channel subfamily A member 1 12 4909893-4918256 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level CAB022365 Uncertain Not detected Tissue enriched 6 cerebral cortex: 13.4 parathyroid gland: 2.1 Cell line enhanced SCLC-21H: 1.2;U-2 OS: 1.0 +DUSP16 KIAA1700, MKP-7, MKP7 ENSG00000111266 Dual specificity phosphatase 16 12 12474210-12562383 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020326 Approved Supported Nucleoplasm Head and neck cancer:1.01e-4 (favourable) Expressed in all Expressed in all adrenal gland: 33.2 Cell line enhanced NTERA-2: 39.3 +CREBL2 ENSG00000111269 CAMP responsive element binding protein like 2 12 12611827-12645108 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043738 Uncertain Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:2.26e-5 (favourable) Expressed in all Expressed in all adrenal gland: 173.3 Expressed in all +ACAD10 MGC5601 ENSG00000111271 Acyl-CoA dehydrogenase family member 10 12 111686056-111757107 Predicted intracellular proteins Evidence at protein level HPA067222 Uncertain Renal cancer:3.71e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 33.6 Expressed in all +ALDH2 ENSG00000111275 Aldehyde dehydrogenase 2 family (mitochondrial) 12 111766887-111817529 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051065 Approved Liver cancer:3.95e-7 (favourable), Renal cancer:5.24e-6 (favourable), Endometrial cancer:2.63e-4 (favourable), Urothelial cancer:7.71e-4 (unfavourable) Expressed in all Expressed in all liver: 441.5 Cell line enhanced HHSteC: 81.5;SK-BR-3: 150.4 +CDKN1B KIP1, P27KIP1 ENSG00000111276 Cyclin dependent kinase inhibitor 1B 12 12715058-12722371 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB003691, CAB021888, HPA059086 Approved Supported Nucleus
Vesicles Liver cancer:3.25e-4 (unfavourable), Colorectal cancer:5.15e-4 (favourable), Renal cancer:8.39e-4 (unfavourable) Expressed in all Expressed in all ovary: 73.1 Mixed +GPRC5D ENSG00000111291 G protein-coupled receptor class C group 5 member D 12 12940775-12952147 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA071909 Approved Head and neck cancer:5.09e-4 (favourable) Mixed Mixed testis: 4.9 Group enriched 10 Karpas-707: 60.7;RPMI-8226: 58.9;U-266/84: 17.2 +NAA25 C12orf30, FLJ13089 ENSG00000111300 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 12 112026689-112109022 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039322 Approved Supported Golgi apparatus
Cytosol Renal cancer:1.32e-8 (unfavourable), Liver cancer:5.53e-5 (unfavourable), Endometrial cancer:2.26e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 9.5 Expressed in all +GSG1 MGC3146 ENSG00000111305 Germ cell associated 1 12 13083560-13103683 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Tissue enhanced Tissue enriched 377 testis: 574.9 duodenum: 1.5 Cell line enhanced fHDF/TERT166: 6.7;LHCN-M2: 8.2;RPTEC TERT1: 9.2;U-2 OS: 6.4 +SCNN1A ENaCalpha, SCNN1 ENSG00000111319 Sodium channel epithelial 1 alpha subunit 12 6346843-6377730 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA012743 Enhanced Renal cancer:9.21e-8 (favourable), Pancreatic cancer:2.30e-4 (unfavourable), Ovarian cancer:8.86e-4 (unfavourable) Mixed Mixed cervix, uterine: 95.1 Cell line enhanced CAPAN-2: 264.6;HBEC3-KT: 145.5;RPTEC TERT1: 78.8;RT4: 91.1;SK-BR-3: 72.7 +LTBR D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3 ENSG00000111321 Lymphotoxin beta receptor 12 6375045-6391571 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB026202, HPA061617 Uncertain Supported Golgi apparatus Liver cancer:5.13e-4 (unfavourable), Renal cancer:5.92e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 89.5 Cell line enhanced HHSteC: 330.0 +OGFOD2 FLJ13491, FLJ37501 ENSG00000111325 2-oxoglutarate and iron dependent oxygenase domain containing 2 12 122974580-122980043 Predicted intracellular proteins Evidence at protein level HPA039448, HPA040306 Approved Supported Nucleoplasm
Nuclear bodies Mixed Expressed in all testis: 23.1 Expressed in all +CDK2AP1 doc-1, DOC1, DORC1, p12DOC-1, ST19 ENSG00000111328 Cyclin dependent kinase 2 associated protein 1 12 123260971-123272334 Predicted intracellular proteins Evidence at protein level CAB019377, HPA057648, HPA068833 Approved Supported Nucleoplasm Renal cancer:5.27e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 294.1 Mixed +OAS3 ENSG00000111331 2'-5'-oligoadenylate synthetase 3 12 112938352-112973249 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041253, HPA041372 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:2.23e-5 (unfavourable) Expressed in all Mixed spleen: 33.4 Cell line enhanced BJ hTERT+ SV40 Large T+: 251.3;BJ hTERT+ SV40 Large T+ RasG12V: 285.0 +OAS2 ENSG00000111335 2'-5'-oligoadenylate synthetase 2 12 112978395-113011723 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB024984, HPA045947 Approved Approved Nucleoplasm
Cytosol Renal cancer:4.31e-6 (unfavourable), Pancreatic cancer:4.63e-4 (unfavourable) Expressed in all Mixed spleen: 59.7 Cell line enhanced BJ hTERT+ SV40 Large T+: 292.1;BJ hTERT+ SV40 Large T+ RasG12V: 247.3;SK-MEL-30: 98.7 +ART4 CD297, DO, DOK1 ENSG00000111339 ADP-ribosyltransferase 4 (Dombrock blood group) 12 14825569-14843495 Blood group antigen proteins, CD markers, Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA075664 Approved Rods & Rings Tissue enhanced Tissue enhanced liver: 27.2;spleen: 26.9 gallbladder: 15.1 Cell line enhanced AN3-CA: 5.6;HEL: 10.9;Hep G2: 4.9;HUVEC TERT2: 22.5 +MGP ENSG00000111341 Matrix Gla protein 12 14881181-14885926 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA013949 Approved Renal cancer:4.15e-6 (unfavourable) Expressed in all Tissue enhanced breast: 4883.1 smooth muscle: 1900.4 Cell line enriched 5 AN3-CA: 9115.9 +RASAL1 RASAL ENSG00000111344 RAS protein activator like 1 12 113098819-113136239 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA041650 Uncertain Approved Plasma membrane
Cell Junctions
Cytosol Endometrial cancer:3.26e-5 (unfavourable) Mixed Tissue enriched 6 parathyroid gland: 118.8 cerebral cortex: 19.4 Cell line enhanced EFO-21: 18.2;REH: 20.3;RPMI-8226: 34.6;RPTEC TERT1: 14.4;U-698: 28.8 +ARHGDIB GDIA2, GDID4, Ly-GDI, RAP1GN1, RhoGDI2 ENSG00000111348 Rho GDP dissociation inhibitor beta 12 14942017-14961728 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018584, HPA051235 Approved Supported Cytosol Renal cancer:1.08e-4 (unfavourable), Urothelial cancer:3.42e-4 (favourable) Expressed in all Expressed in all lymph node: 955.5 Cell line enhanced HEL: 1354.5;HL-60: 1418.5;HMC-1: 1684.2;MOLT-4: 1705.9;REH: 1609.3 +GTF2H3 BTF2, P34, TFIIH ENSG00000111358 General transcription factor IIH subunit 3 12 123633739-123662606 Predicted intracellular proteins Evidence at protein level HPA004844, HPA053562 Uncertain Supported Nucleoplasm Liver cancer:6.72e-8 (unfavourable) Expressed in all Expressed in all cerebral cortex: 26.6 Expressed in all +EIF2B1 EIF-2B, EIF-2Balpha, EIF2B, EIF2BA ENSG00000111361 Eukaryotic translation initiation factor 2B subunit alpha 12 123620406-123633766 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB034258, HPA049509 Approved Supported Cytosol Renal cancer:1.78e-9 (unfavourable), Liver cancer:6.75e-7 (unfavourable) Expressed in all Expressed in all skin: 59.3 Expressed in all +DDX55 KIAA1595 ENSG00000111364 DEAD-box helicase 55 12 123602077-123620941 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039962, HPA044101 Approved Supported Nucleus
Nucleoli
Cytosol Renal cancer:8.97e-12 (unfavourable), Liver cancer:2.11e-9 (unfavourable) Expressed in all Expressed in all skin: 16.4 Expressed in all +SLC38A1 ATA1, NAT2, SAT1 ENSG00000111371 Solute carrier family 38 member 1 12 46183063-46270017 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039460, HPA052272 Uncertain Supported Liver cancer:6.95e-8 (unfavourable), Endometrial cancer:4.76e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 154.6 Mixed +RERGL FLJ22655 ENSG00000111404 RERG like 12 18080869-18320107 Predicted intracellular proteins Evidence at protein level HPA041740 Uncertain Approved Nucleoplasm Mixed Mixed epididymis: 47.0 Cell line enriched 734 REH: 214.1 +ENDOU P11, PP11, PRSS26 ENSG00000111405 Endonuclease, poly(U) specific 12 47709734-47725567 Predicted secreted proteins Evidence at protein level HPA012388, HPA067448 Enhanced Head and neck cancer:6.29e-4 (favourable) Tissue enhanced Group enriched 6 esophagus: 70.3;skin: 24.9 tonsil: 7.7 Cell line enhanced Daudi: 1.6;SK-BR-3: 3.6 +C12orf49 FLJ21415 ENSG00000111412 Chromosome 12 open reading frame 49 12 116710185-116738070 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026905 Uncertain Renal cancer:1.91e-11 (favourable), Liver cancer:8.44e-4 (unfavourable) Expressed in all Tissue enhanced thyroid gland: 62.5 lung: 28.0 Expressed in all +VDR NR1I1, PPP1R163 ENSG00000111424 Vitamin D (1,25- dihydroxyvitamin D3) receptor 12 47841537-47943048 Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters Evidence at protein level CAB004617, HPA047740 Enhanced Nucleoplasm Renal cancer:4.89e-6 (favourable) Expressed in all Tissue enhanced parathyroid gland: 175.9 small intestine: 57.9 Cell line enhanced HDLM-2: 73.7;U-937: 60.2 +FZD10 CD350 ENSG00000111432 Frizzled class receptor 10 12 130162459-130165740 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014484, HPA014485 Uncertain Supported Nucleoplasm Endometrial cancer:5.05e-7 (favourable) Mixed Tissue enhanced cervix, uterine: 9.4;esophagus: 8.8 skin: 5.6 Cell line enhanced AF22: 5.4;BEWO: 6.1;hTCEpi: 2.6;RT4: 2.5 +RFC5 RFC36 ENSG00000111445 Replication factor C subunit 5 12 118013588-118033130 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041037 Supported Approved Nucleoplasm Cervical cancer:8.05e-5 (favourable), Renal cancer:2.30e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 22.2 Expressed in all +STX2 EPIM, EPM, STX2A, STX2B, STX2C ENSG00000111450 Syntaxin 2 12 130789600-130839266 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA038189, HPA069176, CAB079007 Uncertain Supported Approved Nucleus
Cytosol Renal cancer:5.15e-5 (unfavourable) Expressed in all Expressed in all testis: 35.2 Expressed in all +ADGRD1 DKFZp434B1272, GPR133, PGR25 ENSG00000111452 Adhesion G protein-coupled receptor D1 12 130953907-131141469 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA042395 Uncertain Approved Nucleus
Cytosol Liver cancer:9.27e-4 (unfavourable) Mixed Tissue enhanced placenta: 44.7 lung: 32.4 Cell line enhanced BJ: 4.0;fHDF/TERT166: 4.1;HeLa: 6.4;HHSteC: 5.0;HMC-1: 11.4;U-2 OS: 6.6 +COPZ1 CGI-120, COPZ ENSG00000111481 Coatomer protein complex subunit zeta 1 12 54301202-54351849 Predicted intracellular proteins Evidence at protein level Liver cancer:6.40e-5 (unfavourable), Renal cancer:7.45e-5 (unfavourable), Breast cancer:7.84e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 192.5 Expressed in all +TBC1D30 KIAA0984 ENSG00000111490 TBC1 domain family member 30 12 64781193-64881032 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039772, HPA040043 Approved Approved Plasma membrane
Cytosol Endometrial cancer:3.61e-5 (favourable), Lung cancer:5.08e-4 (favourable) Mixed Mixed parathyroid gland: 12.5 Cell line enhanced MCF7: 33.4;RT4: 26.3;SCLC-21H: 35.3;SK-BR-3: 23.3 +CAND1 DKFZp434M1414, KIAA0829, TIP120, TIP120A ENSG00000111530 Cullin associated and neddylation dissociated 1 12 67269281-67319951 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055748, HPA062833, HPA069053 Approved Enhanced Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:1.15e-4 (unfavourable) Expressed in all Expressed in all testis: 51.1 Expressed in all +IL26 AK155, IL-26 ENSG00000111536 Interleukin 26 12 68201351-68225821 Plasma proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enhanced appendix: 1.2;urinary bladder: 1.4 tonsil: 0.9 Cell line enriched 19 HDLM-2: 12.4 +IFNG ENSG00000111537 Interferon gamma 12 68154768-68159747 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB010344 Approved Mixed Tissue enhanced appendix: 4.7;bone marrow: 7.6;lymph node: 7.9 lung: 2.5 Not detected +RAB5B ENSG00000111540 RAB5B, member RAS oncogene family 12 55973913-55996683 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010224, HPA068337 Approved Supported Vesicles Breast cancer:2.24e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 175.6 Expressed in all +MDM1 ENSG00000111554 Mdm1 nuclear protein 12 68272443-68332381 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040411, HPA041594 Uncertain Supported Centrosome
Cytosol Cervical cancer:6.01e-4 (favourable) Expressed in all Expressed in all testis: 37.5 Expressed in all +NUP107 NUP84 ENSG00000111581 Nucleoporin 107 12 68686734-68745809 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA031679 Uncertain Nucleoplasm
Nuclear membrane
Centrosome Liver cancer:3.12e-9 (unfavourable), Renal cancer:1.28e-6 (unfavourable) Expressed in all Expressed in all testis: 38.1 Expressed in all +CNOT2 CDC36, NOT2, NOT2H ENSG00000111596 CCR4-NOT transcription complex subunit 2 12 70242994-70354993 Predicted intracellular proteins Evidence at protein level HPA067711 Approved Approved Nucleus
Cytosol Renal cancer:8.63e-5 (unfavourable), Liver cancer:2.21e-4 (unfavourable), Melanoma:6.86e-4 (unfavourable) Expressed in all Expressed in all skin: 53.9 Expressed in all +TIMELESS hTIM, TIM, TIM1 ENSG00000111602 Timeless circadian clock 12 56416373-56449403 Predicted intracellular proteins Evidence at protein level HPA060655 Enhanced Supported Nucleus Melanoma:1.06e-5 (unfavourable), Renal cancer:2.61e-5 (unfavourable), Liver cancer:3.61e-4 (unfavourable) Expressed in all Mixed lymph node: 18.2 Expressed in all +CPSF6 CFIM, CFIM68, HPBRII-4, HPBRII-7 ENSG00000111605 Cleavage and polyadenylation specific factor 6 12 69239537-69274358 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039973 Supported Enhanced Nucleoplasm
Nuclear speckles Liver cancer:1.91e-6 (unfavourable), Renal cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all lymph node: 55.2 Expressed in all +KRR1 HRB2, RIP-1 ENSG00000111615 KRR1, small subunit processome component homolog 12 75490861-75511636 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043433, HPA051690 Approved Enhanced Nucleus
Nucleoli Expressed in all Expressed in all bone marrow: 27.7 Expressed in all +MRPL51 bMRP64, CDA09, HSPC241, MRP64 ENSG00000111639 Mitochondrial ribosomal protein L51 12 6491886-6493841 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA039923 Approved Supported Mitochondria Expressed in all Expressed in all testis: 234.8 Expressed in all +GAPDH GAPD ENSG00000111640 Glyceraldehyde-3-phosphate dehydrogenase 12 6533927-6538374 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005197, CAB016392, HPA040067, HPA061280 Supported Enhanced Plasma membrane
Cytosol Renal cancer:6.25e-10 (unfavourable), Liver cancer:1.79e-6 (unfavourable) Expressed in all Expressed in all skeletal muscle: 9869.6 Expressed in all +NOP2 NOL1, NOP120, NSUN1, p120 ENSG00000111641 NOP2 nucleolar protein 12 6556863-6568691 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040119 Supported Supported Nucleoli Renal cancer:2.35e-10 (unfavourable), Liver cancer:1.12e-5 (unfavourable) Expressed in all Expressed in all lymph node: 35.6 Expressed in all +CHD4 Mi-2b, Mi2-BETA ENSG00000111642 Chromodomain helicase DNA binding protein 4 12 6570083-6607476 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA012008 Supported Enhanced Nucleus Liver cancer:6.03e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 119.0 Expressed in all +ACRBP CT23, OY-TES-1, SP32 ENSG00000111644 Acrosin binding protein 12 6638075-6647460 Predicted secreted proteins Evidence at protein level HPA039081, HPA039082 Enhanced Approved Nucleoplasm
Vesicles Mixed Tissue enriched 19 testis: 432.5 thyroid gland: 22.6 Cell line enhanced HMC-1: 5.8;U-266/70: 11.3;U-266/84: 7.3 +UHRF1BP1L KIAA0701 ENSG00000111647 UHRF1 binding protein 1 like 12 100028455-100142848 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA039671, HPA040399 Uncertain Approved Plasma membrane Expressed in all Mixed cerebral cortex: 32.9 Expressed in all +COPS7A CSN7A ENSG00000111652 COP9 signalosome subunit 7A 12 6723741-6731875 Predicted intracellular proteins Evidence at protein level HPA026915 Supported Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 92.3 Expressed in all +ING4 my036, p29ING4 ENSG00000111653 Inhibitor of growth family member 4 12 6650280-6663148 Predicted intracellular proteins Evidence at protein level HPA031817, HPA057338 Approved Supported Nucleus Lung cancer:5.16e-4 (favourable) Expressed in all Expressed in all fallopian tube: 43.7 Expressed in all +GNB3 ENSG00000111664 G protein subunit beta 3 12 6839954-6847393 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA040736 Approved Approved Golgi apparatus
Plasma membrane Tissue enhanced Mixed smooth muscle: 3.8 Cell line enhanced NTERA-2: 12.8;U-698: 22.7 +CDCA3 GRCC8, TOME-1 ENSG00000111665 Cell division cycle associated 3 12 6844793-6852066 Predicted intracellular proteins Evidence at protein level HPA026587 Approved Cytosol Liver cancer:6.51e-5 (unfavourable), Lung cancer:9.77e-5 (unfavourable) Mixed Tissue enhanced testis: 30.7 small intestine: 19.3 Mixed +CHPT1 CPT1 ENSG00000111666 Choline phosphotransferase 1 12 101696947-101744140 Enzymes, Predicted membrane proteins Evidence at protein level HPA067643 Approved Approved Vesicles Thyroid cancer:7.41e-4 (favourable) Expressed in all Expressed in all breast: 125.6 Expressed in all +USP5 IsoT ENSG00000111667 Ubiquitin specific peptidase 5 12 6852128-6866632 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006756 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 87.5 Expressed in all +TPI1 ENSG00000111669 Triosephosphate isomerase 1 12 6867119-6870948 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA050924, HPA053568 Uncertain Enhanced Nucleoplasm Liver cancer:1.04e-5 (unfavourable), Renal cancer:6.54e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 942.7 Expressed in all +GNPTAB GNPTA, KIAA1208, MGC4170 ENSG00000111670 N-acetylglucosamine-1-phosphate transferase alpha and beta subunits 12 101745497-101830938 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014558, HPA042343 Approved Supported Golgi apparatus Endometrial cancer:8.48e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 63.1 Expressed in all +SPSB2 GRCC9, SSB-2 ENSG00000111671 SplA/ryanodine receptor domain and SOCS box containing 2 12 6870935-6889358 Predicted intracellular proteins Evidence at protein level HPA055225 Approved Liver cancer:2.62e-4 (unfavourable) Expressed in all Expressed in all lung: 12.6 Expressed in all +ENO2 ENSG00000111674 Enolase 2 12 6913745-6923698 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000063, HPA068284, HPA068721, CAB073539, CAB079023 Enhanced Supported Supported Plasma membrane
Cytosol Renal cancer:7.89e-11 (unfavourable), Liver cancer:5.15e-4 (unfavourable), Colorectal cancer:6.96e-4 (unfavourable) Expressed in all Tissue enriched 7 cerebral cortex: 431.0 parathyroid gland: 64.8 Cell line enhanced U-87 MG: 368.8 +ATN1 B37, D12S755E, DRPLA ENSG00000111676 Atrophin 1 12 6924463-6942321 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031619 Enhanced Enhanced Nucleoplasm Liver cancer:7.20e-4 (unfavourable) Expressed in all Expressed in all ovary: 139.5 Expressed in all +C12orf57 C10, GRCC10 ENSG00000111678 Chromosome 12 open reading frame 57 12 6942978-6946003 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046182, HPA059163, HPA066043 Approved Supported Nuclear speckles Renal cancer:2.32e-7 (unfavourable), Pancreatic cancer:8.74e-4 (favourable) Expressed in all Expressed in all ovary: 522.5 Expressed in all +PTPN6 HCP, HCPH, PTP-1C, SHP-1, SHP1 ENSG00000111679 Protein tyrosine phosphatase, non-receptor type 6 12 6946468-6961316 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001466, CAB004572, CAB072845 Enhanced Supported Nucleus
Nucleoli Urothelial cancer:2.64e-8 (favourable), Cervical cancer:1.87e-4 (favourable), Colorectal cancer:5.42e-4 (unfavourable), Endometrial cancer:6.65e-4 (favourable) Expressed in all Mixed lymph node: 161.5 Cell line enhanced HEL: 143.6;HMC-1: 527.9;THP-1: 163.9 +LPCAT3 C3F, MBOAT5, nessy, OACT5 ENSG00000111684 Lysophosphatidylcholine acyltransferase 3 12 6976186-7018510 Enzymes, Predicted membrane proteins Evidence at protein level Renal cancer:4.89e-5 (favourable) Expressed in all Expressed in all duodenum: 123.0 Expressed in all +NT5DC3 FLJ11266, TU12B1-TY ENSG00000111696 5'-nucleotidase domain containing 3 12 103770453-103841197 Predicted secreted proteins Evidence at protein level HPA041634 Approved Mitochondria
Cytosol Renal cancer:5.72e-6 (unfavourable), Liver cancer:4.31e-4 (unfavourable), Urothelial cancer:8.11e-4 (unfavourable) Expressed in all Mixed endometrium: 16.0 Mixed +SLCO1B3 OATP1B3, OATP8, SLC21A8 ENSG00000111700 Solute carrier organic anion transporter family member 1B3 12 20810702-20916911 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA004943, HPA050892 Enhanced Supported Plasma membrane Tissue enhanced Tissue enriched 7 liver: 138.9 cervix, uterine: 19.5 Cell line enhanced A-431: 56.7;A549: 15.8;CAPAN-2: 11.0;PC-3: 16.0;U-2 OS: 15.2 +APOBEC1 APOBEC-1, BEDP, CDAR1, HEPR ENSG00000111701 Apolipoprotein B mRNA editing enzyme catalytic subunit 1 12 7649400-7665903 Enzymes, Predicted intracellular proteins Evidence at protein level Group enriched Group enriched 21 duodenum: 31.9;small intestine: 31.0 stomach: 1.5 Cell line enriched 17 CAPAN-2: 2.4 +NANOG FLJ12581, FLJ40451 ENSG00000111704 Nanog homeobox 12 7787794-7799141 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB019380 Supported Tissue enriched Tissue enhanced testis: 1.9 lung: 0.7 Cell line enriched 438 NTERA-2: 118.9 +SUDS3 FLJ00052, SAP45, SDS3 ENSG00000111707 SDS3 homolog, SIN3A corepressor complex component 12 118376380-118418031 Predicted secreted proteins Evidence at protein level HPA040402, HPA041972 Approved Supported Nuclear bodies
Cytosol Expressed in all Expressed in all parathyroid gland: 36.1 Expressed in all +GOLT1B CGI-141, GOT1, YMR292W ENSG00000111711 Golgi transport 1B 12 21501781-21518408 Predicted membrane proteins Evidence at protein level HPA055909, HPA066383 Approved Supported Nucleoplasm
Vesicles Renal cancer:4.83e-10 (unfavourable), Liver cancer:1.99e-8 (unfavourable), Pancreatic cancer:2.32e-4 (unfavourable) Expressed in all Expressed in all placenta: 42.4 Expressed in all +GYS2 ENSG00000111713 Glycogen synthase 2 12 21536189-21604847 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039482 Approved Liver cancer:7.62e-5 (favourable) Tissue enriched Tissue enriched 23 liver: 91.8 adipose tissue: 3.9 Cell line enhanced CACO-2: 1.0 +LDHB ENSG00000111716 Lactate dehydrogenase B 12 21635342-21757857 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004641, HPA019007 Enhanced Enhanced Cytosol Renal cancer:2.51e-4 (favourable) Expressed in all Expressed in all kidney: 1790.8 Expressed in all +PRKAB1 ENSG00000111725 Protein kinase AMP-activated non-catalytic subunit beta 1 12 119667753-119681630 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA004247, CAB005058 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:5.40e-9 (favourable), Endometrial cancer:8.66e-4 (favourable) Expressed in all Expressed in all kidney: 53.5 Expressed in all +CMAS ENSG00000111726 Cytidine monophosphate N-acetylneuraminic acid synthetase 12 22046174-22065674 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039905 Supported Uncertain Nucleoli
Cytosol Renal cancer:7.19e-4 (unfavourable) Expressed in all Expressed in all testis: 127.9 Expressed in all +HCFC2 HCF-2 ENSG00000111727 Host cell factor C2 12 104064457-104106524 Predicted intracellular proteins Evidence at protein level HPA006227 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 17.1 Mixed +ST8SIA1 SIAT8, SIAT8A ENSG00000111728 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 12 22063773-22437041 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026775 Approved Mixed Mixed cerebral cortex: 9.0 Cell line enhanced AF22: 6.4;SK-MEL-30: 4.8;WM-115: 6.4 +CLEC4A CD367, CLECSF6, DCIR, DDB27 ENSG00000111729 C-type lectin domain family 4 member A 12 8082269-8138607 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007842 Uncertain Expressed in all Tissue enhanced appendix: 30.7 spleen: 17.1 Not detected +C2CD5 CDP138, KIAA0528 ENSG00000111731 C2 calcium dependent domain containing 5 12 22448583-22544546 Predicted intracellular proteins Evidence at protein level HPA046194 Approved Approved Microtubule organizing center
Cytosol Expressed in all Expressed in all parathyroid gland: 51.5 Expressed in all +AICDA AID, ARP2, CDA2, HIGM2 ENSG00000111732 Activation induced cytidine deaminase 12 8602166-8612871 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 11 appendix: 4.9;lymph node: 18.7;tonsil: 11.0 spleen: 1.0 Group enriched 5 Daudi: 101.6;U-698: 81.2 +RAB35 H-ray ENSG00000111737 RAB35, member RAS oncogene family 12 120095095-120117502 Predicted intracellular proteins Evidence at protein level HPA054146 Approved Liver cancer:6.46e-6 (unfavourable), Lung cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all appendix: 37.8 Expressed in all +PHC1 EDR1, HPH1, RAE28 ENSG00000111752 Polyhomeotic homolog 1 12 8913896-8941467 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA006973 Approved Supported Nucleus Tissue enriched Expressed in all testis: 80.4 Group enriched 6 BEWO: 158.3;NTERA-2: 593.1 +COX6A1 COX6A ENSG00000111775 Cytochrome c oxidase subunit 6A1 12 120438090-120440742 Disease related genes, Predicted membrane proteins Evidence at protein level HPA062394 Approved Supported Mitochondria Renal cancer:6.50e-7 (favourable) Expressed in all Expressed in all duodenum: 572.6 Expressed in all +AL021546.6 ENSG00000111780 12 120438198-120460006 Predicted intracellular proteins Evidence at protein level HPA062394 Uncertain Approved Mitochondria Not detected Not detected colon: 0.9 Cell line enhanced CACO-2: 7.5;HEK 293: 10.3;U-266/84: 7.5 +RFX4 ENSG00000111783 Regulatory factor X4 12 106582907-106762803 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050527 Enhanced Approved Nucleus Tissue enriched Group enriched 236 cerebral cortex: 30.8;testis: 135.8 prostate: 0.3 Cell line enriched 13 AF22: 47.1 +RIC8B FLJ10620, hSyn, RIC8 ENSG00000111785 RIC8 guanine nucleotide exchange factor B 12 106774595-106889316 Predicted intracellular proteins Evidence at protein level HPA042746 Approved Approved Centrosome
Cytosol Expressed in all Mixed parathyroid gland: 21.8 Mixed +SRSF9 SFRS9, SRp30c ENSG00000111786 Serine and arginine rich splicing factor 9 12 120461668-120469793 Predicted intracellular proteins Evidence at protein level HPA049849 Enhanced Approved Nucleoplasm Liver cancer:9.85e-7 (unfavourable), Melanoma:7.80e-4 (unfavourable) Expressed in all Expressed in all testis: 139.2 Expressed in all +FGFR1OP2 DKFZp564O1863 ENSG00000111790 FGFR1 oncogene partner 2 12 26938383-26966650 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038308, HPA038696 Supported Approved Mitochondria Expressed in all Expressed in all ovary: 73.7 Expressed in all +KLRB1 CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A ENSG00000111796 Killer cell lectin like receptor B1 12 9594551-9607886 CD markers, Predicted membrane proteins Evidence at protein level HPA039113 Approved Uncertain Nucleoplasm
Cytosol Endometrial cancer:1.42e-5 (favourable), Breast cancer:3.51e-5 (favourable), Head and neck cancer:6.99e-5 (favourable), Thyroid cancer:5.61e-4 (favourable) Mixed Mixed spleen: 40.7 Not detected +COL12A1 COL12A1L ENSG00000111799 Collagen type XII alpha 1 chain 6 75084326-75206051 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA009143, HPA070695 Uncertain Approved Nucleus Renal cancer:1.69e-9 (unfavourable) Expressed in all Mixed endometrium: 113.7 Cell line enhanced fHDF/TERT166: 1109.7;SiHa: 894.9 +BTN3A3 BTF3, BTN3.3 ENSG00000111801 Butyrophilin subfamily 3 member A3 6 26440472-26453415 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007904, HPA011871 Enhanced Renal cancer:2.42e-5 (unfavourable), Ovarian cancer:1.80e-4 (favourable) Expressed in all Mixed spleen: 64.0 Cell line enhanced ASC TERT1: 43.5;BJ hTERT+ SV40 Large T+ RasG12V: 41.9 +TDP2 TTRAP ENSG00000111802 Tyrosyl-DNA phosphodiesterase 2 6 24649977-24667033 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB073398, HPA074011 Enhanced Supported Nucleoplasm
Nuclear bodies Ovarian cancer:2.53e-7 (favourable), Urothelial cancer:1.47e-5 (favourable), Prostate cancer:1.86e-4 (unfavourable) Expressed in all Expressed in all small intestine: 189.4 Expressed in all +FRK GTK, PTK5, RAK ENSG00000111816 Fyn related Src family tyrosine kinase 6 115931149-116060758 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB025217, HPA030479 Approved Supported Nucleus
Cytosol Renal cancer:9.66e-7 (favourable) Mixed Mixed kidney: 10.0 Mixed +DSE DSEPI, SART2 ENSG00000111817 Dermatan sulfate epimerase 6 116254173-116444860 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014764, HPA052151 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:1.50e-4 (unfavourable), Cervical cancer:3.36e-4 (unfavourable), Ovarian cancer:6.34e-4 (unfavourable) Mixed Mixed appendix: 36.2 Mixed +RWDD1 PTD013 ENSG00000111832 RWD domain containing 1 6 116571367-116597675 Predicted intracellular proteins Evidence at protein level HPA028712, HPA028713 Approved Liver cancer:5.16e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 61.8 Expressed in all +RSPH4A CILD11, dJ412I7.1, FLJ37974, RSHL3, RSPH6B ENSG00000111834 Radial spoke head 4 homolog A 6 116616479-116632985 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031196, HPA031197, HPA031198 Enhanced Supported Nucleus Tissue enhanced Tissue enriched 8 fallopian tube: 59.7 lung: 7.1 Cell line enhanced RPMI-8226: 2.3;U-266/84: 1.7 +MAK dJ417M14.2, RP62 ENSG00000111837 Male germ cell associated kinase 6 10762723-10838555 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Mixed Group enriched 9 fallopian tube: 9.7;parathyroid gland: 10.2;testis: 20.4 lung: 1.4 Cell line enhanced HDLM-2: 1.4 +TMEM14C bA421M1.6, C6orf53, HSPC194, NET26 ENSG00000111843 Transmembrane protein 14C 6 10722915-10731129 Predicted membrane proteins Evidence at protein level Liver cancer:3.66e-4 (unfavourable) Expressed in all Expressed in all prostate: 148.2 Expressed in all +PAK1IP1 bA421M1.5, FLJ20624, hPIP1, MAK11, PIP1, WDR84 ENSG00000111845 PAK1 interacting protein 1 6 10694695-10709782 Predicted intracellular proteins Evidence at protein level HPA030111, HPA030112 Supported Supported Nucleoplasm
Nucleoli Renal cancer:7.02e-8 (unfavourable), Liver cancer:1.35e-6 (unfavourable) Expressed in all Expressed in all prostate: 104.5 Expressed in all +GCNT2 bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3 ENSG00000111846 Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 6 10492223-10629368 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026776 Approved Supported Golgi apparatus Mixed Tissue enhanced prostate: 55.7 breast: 13.9 Cell line enhanced CACO-2: 39.6;EFO-21: 67.0 +SMIM8 C6orf162, dJ102H19.2, DKFZP586E1923 ENSG00000111850 Small integral membrane protein 8 6 87322583-87399749 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007401, HPA067453 Approved Approved Vesicles Expressed in all Mixed cerebral cortex: 13.9 Expressed in all +NEDD9 CAS-L, CASS2, HEF1 ENSG00000111859 Neural precursor cell expressed, developmentally down-regulated 9 6 11183298-11382348 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009720, HPA038768, HPA039270 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all lung: 103.4 Cell line enhanced EFO-21: 129.1 +CEP85L bA57K17.2, C6orf204, NY-BR-15 ENSG00000111860 Centrosomal protein 85 like 6 118460772-118710075 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029137, HPA029138, HPA029139 Uncertain Mixed Tissue enhanced testis: 53.7 lymph node: 15.6 Cell line enhanced BEWO: 24.8 +ADTRP AIG1L, C6orf105, dJ413H6.1 ENSG00000111863 Androgen dependent TFPI regulating protein 6 11712054-11807046 Predicted membrane proteins Evidence at transcript level HPA048113 Uncertain Uncertain Nucleoli Renal cancer:1.13e-5 (unfavourable) Mixed Tissue enhanced small intestine: 79.4 duodenum: 61.1 Cell line enhanced HUVEC TERT2: 62.0;TIME: 33.0;U-138 MG: 25.7;U-266/84: 23.2 +ASF1A CIA, DKFZP547E2110 ENSG00000111875 Anti-silencing function 1A histone chaperone 6 118894220-118909167 Predicted intracellular proteins Evidence at protein level HPA030502, HPA071495 Enhanced Nucleus Liver cancer:5.02e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.7 Expressed in all +MCM9 C6orf61, dJ329L24.3, FLJ20170, MCMDC1, MGC35304 ENSG00000111877 Minichromosome maintenance 9 homologous recombination repair factor 6 118813442-118935162 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA031137 Approved Approved Nucleoplasm Expressed in all Mixed epididymis: 15.5 Expressed in all +FAM184A C6orf60, FLJ13942 ENSG00000111879 Family with sequence similarity 184 member A 6 118959763-119149387 Predicted intracellular proteins Evidence at protein level HPA034571, HPA034572, HPA041955 Uncertain Supported Nucleoplasm
Golgi apparatus
Cytosol Mixed Tissue enhanced placenta: 46.0;testis: 45.3 cerebral cortex: 25.1 Cell line enhanced AF22: 19.5;HEK 293: 10.7;K-562: 15.2;SCLC-21H: 15.0 +RNGTT hCAP, HCE, HCE1 ENSG00000111880 RNA guanylyltransferase and 5'-phosphatase 6 88610272-88963721 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003750 Approved Approved Nucleoplasm Liver cancer:1.37e-4 (unfavourable) Expressed in all Mixed lymph node: 21.1 Expressed in all +MAN1A1 ENSG00000111885 Mannosidase alpha class 1A member 1 6 119177209-119349761 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB037058, HPA053198, HPA063561 Uncertain Supported Golgi apparatus Expressed in all Expressed in all placenta: 112.4 Cell line enhanced ASC diff: 187.5;Karpas-707: 157.8;U-266/70: 224.6 +GABRR2 ENSG00000111886 Gamma-aminobutyric acid type A receptor rho2 subunit 6 89257208-89315299 FDA approved drug targets, Predicted membrane proteins Evidence at transcript level Not detected Not detected adrenal gland,appendix,cerebral cortex,endometrium,gallbladder,lymph node,skin,spleen,testis,thyroid gland: 0.1 Not detected +SERINC1 KIAA1253, TDE1L, TDE2, TMS-2 ENSG00000111897 Serine incorporator 1 6 122443354-122471822 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA035738, HPA035739 Uncertain Approved Cytosol Expressed in all Expressed in all cerebral cortex: 615.4 Expressed in all +HDDC2 C6orf74, CGI-130, dJ167O5.2 ENSG00000111906 HD domain containing 2 6 125219962-125302078 Predicted intracellular proteins Evidence at protein level HPA035677 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all testis: 117.1 Expressed in all +TPD52L1 D53, hD53 ENSG00000111907 Tumor protein D52-like 1 6 125119049-125264407 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027915, HPA027916 Enhanced Approved Plasma membrane
Cell Junctions
Cytosol Renal cancer:3.26e-4 (favourable), Thyroid cancer:3.97e-4 (favourable), Urothelial cancer:5.34e-4 (unfavourable) Expressed in all Tissue enhanced adrenal gland: 320.2 salivary gland: 126.1 Cell line enhanced AN3-CA: 249.0;hTCEpi: 169.3;MCF7: 277.5;RPTEC TERT1: 204.5 +HINT3 FLJ33126 ENSG00000111911 Histidine triad nucleotide binding protein 3 6 125956781-125980244 Predicted intracellular proteins Evidence at protein level HPA027914 Approved Supported Nucleoli
Mitochondria
Cytosol Renal cancer:1.05e-6 (favourable), Breast cancer:4.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 49.7 Expressed in all +NCOA7 dJ187J11.3, ERAP140, TLDC4 ENSG00000111912 Nuclear receptor coactivator 7 6 125781161-125932030 Predicted intracellular proteins Evidence at protein level HPA030289, HPA030290, HPA030291, HPA030292 Approved Approved Nuclear bodies
Golgi apparatus Renal cancer:1.78e-6 (favourable) Expressed in all Expressed in all urinary bladder: 88.4 Expressed in all +FAM65B C6orf32, DIFF48, KIAA0386, MYONAP ENSG00000111913 Family with sequence similarity 65 member B 6 24804282-25042018 Disease related genes, Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced lymph node: 92.5 spleen: 73.1 Cell line enhanced AF22: 30.2;Daudi: 47.4;fHDF/TERT166: 47.6 +SASH1 dJ323M4.1, KIAA0790, SH3D6A ENSG00000111961 SAM and SH3 domain containing 1 6 148272304-148552050 Predicted intracellular proteins Evidence at protein level HPA029947, HPA029949 Uncertain Approved Nucleoplasm
Cytosol Endometrial cancer:2.42e-4 (unfavourable) Expressed in all Mixed thyroid gland: 63.6 Cell line enhanced ASC diff: 133.3;WM-115: 91.6 +UST 2OST ENSG00000111962 Uronyl 2-sulfotransferase 6 148747328-149076990 Predicted membrane proteins Evidence at protein level HPA032022 Approved Expressed in all Tissue enhanced thyroid gland: 49.9 adrenal gland: 16.9 Mixed +ULBP1 RAET1I ENSG00000111981 UL16 binding protein 1 6 149964007-149973710 Predicted membrane proteins Evidence at protein level HPA007547, HPA071005 Enhanced Approved Plasma membrane
Actin filaments
Cytosol Mixed Tissue enhanced testis: 11.0 thyroid gland: 3.5 Cell line enhanced HAP1: 35.9 +FBXO5 EMI1, FBX5, Fbxo31 ENSG00000112029 F-box protein 5 6 152970519-152983579 Predicted intracellular proteins Evidence at protein level CAB008106, HPA029048 Approved Supported Nucleoplasm Stomach cancer:8.65e-4 (favourable) Expressed in all Mixed bone marrow: 27.1 Expressed in all +MTRF1L HMRF1L, mtRF1a ENSG00000112031 Mitochondrial translational release factor 1 like 6 152987362-153002685 Predicted intracellular proteins Evidence at protein level HPA036367 Uncertain Breast cancer:4.82e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 13.0 Expressed in all +PPARD FAAR, NR1C2, NUC1, NUCII ENSG00000112033 Peroxisome proliferator activated receptor delta 6 35342558-35428191 FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017635 Approved Liver cancer:4.57e-4 (unfavourable) Expressed in all Expressed in all placenta: 40.2 Expressed in all +OPRM1 MOR1 ENSG00000112038 Opioid receptor mu 1 6 154010496-154246867 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA014509, HPA067435 Enhanced Supported Not detected Tissue enhanced testis: 4.1 adrenal gland,esophagus: 1.2 Cell line enriched 29 SH-SY5Y: 7.7 +FANCE FACE, FAE ENSG00000112039 Fanconi anemia complementation group E 6 35452361-35467103 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB014893 Enhanced Supported Nucleoplasm Liver cancer:2.08e-9 (unfavourable), Endometrial cancer:6.25e-4 (unfavourable) Expressed in all Mixed skin: 16.1 Expressed in all +TULP1 LCA15, RP14, TUBL1 ENSG00000112041 Tubby like protein 1 6 35497874-35512938 Disease related genes, Predicted intracellular proteins Evidence at protein level Mixed Not detected prostate: 0.7 Cell line enhanced BEWO: 2.6;MCF7: 1.2 +SLC26A8 ENSG00000112053 Solute carrier family 26 member 8 6 35943514-36024868 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA038081 Enhanced Not detected Tissue enriched 27 testis: 76.1 bone marrow: 2.8 Not detected +MAPK14 CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15 ENSG00000112062 Mitogen-activated protein kinase 14 6 36027677-36111236 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB010285, CAB040578, HPA051825 Approved Supported Nuclear speckles Expressed in all Expressed in all placenta: 63.2 Expressed in all +RHAG CD241, RH50A, SLC42A1 ENSG00000112077 Rh-associated glycoprotein 6 49605158-49636839 CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046051, HPA055331 Approved Uncertain Endoplasmic reticulum Not detected Tissue enriched 24 bone marrow: 73.7 placenta: 3.1 Group enriched 223 HEL: 448.1;K-562: 429.7 +KCTD20 C6orf69, dJ108K11.3, MGC14254 ENSG00000112078 Potassium channel tetramerization domain containing 20 6 36442767-36491143 Predicted intracellular proteins Evidence at protein level HPA030092 Approved Approved Nuclear speckles
Endoplasmic reticulum Glioma:7.39e-4 (favourable), Renal cancer:8.02e-4 (unfavourable), Liver cancer:8.32e-4 (unfavourable), Thyroid cancer:9.31e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 47.0 Expressed in all +STK38 NDR ENSG00000112079 Serine/threonine kinase 38 6 36493892-36547470 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004673, HPA038623, HPA051324 Uncertain Approved Cytosol Melanoma:9.44e-5 (unfavourable) Expressed in all Expressed in all rectum: 40.3 Expressed in all +SRSF3 SFRS3, SRp20 ENSG00000112081 Serine and arginine rich splicing factor 3 6 36594353-36605600 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012986, HPA056981 Supported Supported Nucleoplasm Liver cancer:6.22e-5 (unfavourable), Ovarian cancer:1.37e-4 (favourable), Melanoma:1.95e-4 (unfavourable), Renal cancer:2.02e-4 (unfavourable), Colorectal cancer:2.56e-4 (favourable) Expressed in all Expressed in all lymph node: 139.5 Expressed in all +SOD2 ENSG00000112096 Superoxide dismutase 2 6 159669057-159762529 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001814, CAB002013 Supported Renal cancer:1.72e-4 (unfavourable) Expressed in all Expressed in all appendix: 734.4 Expressed in all +MRPL18 HSPC071 ENSG00000112110 Mitochondrial ribosomal protein L18 6 159789812-159798436 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA028774, HPA028775 Enhanced Renal cancer:9.02e-5 (unfavourable), Liver cancer:3.61e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 85.9 Expressed in all +IL17A CTLA8, IL-17, IL-17A, IL17 ENSG00000112115 Interleukin 17A 6 52186387-52190638 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA052258 Uncertain Not detected Tissue enhanced appendix: 1.0;tonsil: 1.3;urinary bladder: 1.5 gallbladder: 0.3 Group enriched 16 Karpas-707: 1.9;U-266/84: 1.2 +IL17F IL-17F, ML-1, ML1 ENSG00000112116 Interleukin 17F 6 52236681-52244537 Disease related genes, Predicted secreted proteins Evidence at protein level Not detected Tissue enhanced tonsil: 1.8 urinary bladder: 0.9 Not detected +MCM3 ENSG00000112118 Minichromosome maintenance complex component 3 6 52264009-52284881 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002162, HPA004789, HPA004790 Supported Enhanced Nucleoplasm Thyroid cancer:3.13e-5 (favourable), Melanoma:4.40e-5 (unfavourable), Liver cancer:1.40e-4 (unfavourable), Cervical cancer:1.89e-4 (favourable) Expressed in all Expressed in all lymph node: 80.8 Expressed in all +RNF8 KIAA0646 ENSG00000112130 Ring finger protein 8 6 37353972-37394738 Enzymes, Predicted intracellular proteins Evidence at protein level HPA050731, HPA064925 Approved Supported Nucleus
Cytosol Liver cancer:3.33e-5 (unfavourable), Prostate cancer:4.99e-5 (unfavourable), Melanoma:1.91e-4 (unfavourable) Expressed in all Mixed testis: 18.5 Expressed in all +PHACTR1 dJ257A7.2, KIAA1733, RPEL1 ENSG00000112137 Phosphatase and actin regulator 1 6 12716805-13290484 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029755, HPA029756, HPA029757 Enhanced Uncertain Plasma membrane Renal cancer:5.48e-6 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 26.6 bone marrow: 15.6 Cell line enhanced HMC-1: 33.9;U-266/70: 72.3;U-266/84: 46.3 +MDGA1 GPIM, MAMDC3 ENSG00000112139 MAM domain containing glycosylphosphatidylinositol anchor 1 6 37630679-37699306 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031235, HPA050382 Approved Supported Golgi apparatus
Plasma membrane Mixed Mixed parathyroid gland: 10.1 Mixed +ICK KIAA0936, LCK2, MGC46090, MRK ENSG00000112144 Intestinal cell kinase 6 53001279-53061802 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000791, HPA001113 Approved Approved Nucleoli fibrillar center Expressed in all Mixed adrenal gland: 23.1 Expressed in all +FBXO9 FBX9, NY-REN-57 ENSG00000112146 F-box protein 9 6 53051991-53100873 Predicted intracellular proteins Evidence at protein level HPA064246 Approved Centrosome Ovarian cancer:1.51e-4 (favourable), Pancreatic cancer:1.82e-4 (favourable) Expressed in all Expressed in all adrenal gland: 107.5 Expressed in all +CD83 BL11, HB15 ENSG00000112149 CD83 molecule 6 14117256-14136918 CD markers, Predicted membrane proteins Evidence at protein level CAB002509, HPA041454 Enhanced Approved Vesicles Renal cancer:3.49e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 130.9 tonsil: 64.1 Cell line enhanced Daudi: 54.6;HDLM-2: 64.1;U-698: 80.4 +MDN1 KIAA0301, Rea1 ENSG00000112159 Midasin AAA ATPase 1 6 89642499-89819723 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029666, HPA029667, HPA029668, HPA029669 Uncertain Approved Nucleus
Nucleoli
Intermediate filaments
Cytosol Expressed in all Mixed parathyroid gland: 13.4 Expressed in all +GLP1R ENSG00000112164 Glucagon like peptide 1 receptor 6 39048798-39087743 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Mixed Tissue enhanced cerebral cortex: 1.9;heart muscle: 1.8 pancreas: 1.5 Cell line enhanced NTERA-2: 1.3;SCLC-21H: 3.7 +SAYSD1 C6orf64, FLJ11101 ENSG00000112167 SAYSVFN motif domain containing 1 6 39104064-39115189 Predicted membrane proteins Evidence at protein level HPA007959 Approved Enhanced Vesicles Expressed in all Tissue enriched 6 testis: 85.8 prostate: 14.6 Mixed +BMP5 ENSG00000112175 Bone morphogenetic protein 5 6 55753645-55875564 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced placenta: 102.6 prostate: 24.1 Group enriched 9 AF22: 27.4;U-2 OS: 22.4 +BACH2 BTBD25 ENSG00000112182 BTB domain and CNC homolog 2 6 89926529-90296908 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051384, HPA058384 Enhanced Supported Nucleus
Cytosol Mixed Tissue enhanced lymph node: 21.2 tonsil: 12.1 Cell line enhanced Daudi: 101.9;U-698: 57.4 +RBM24 dJ259A10.1, FLJ30829, RNPC6 ENSG00000112183 RNA binding motif protein 24 6 17281346-17293875 Predicted intracellular proteins Evidence at protein level HPA066927, HPA067231 Enhanced Enhanced Nucleoplasm
Cytosol Mixed Tissue enhanced heart muscle: 90.9;skeletal muscle: 109.8 endometrium: 51.6 Cell line enhanced LHCN-M2: 49.0;RH-30: 57.9;T-47d: 26.5 +CAP2 ENSG00000112186 CAP, adenylate cyclase-associated protein, 2 (yeast) 6 17393216-17557792 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA050530, HPA054147 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Tissue enhanced cerebral cortex: 125.1;skeletal muscle: 220.8 heart muscle: 70.1 Mixed +TREML2 C6orf76, dJ238O23.1, FLJ13693, TLT2 ENSG00000112195 Triggering receptor expressed on myeloid cells like 2 6 41190277-41201194 Plasma proteins, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced appendix: 9.3;bone marrow: 10.0;lymph node: 11.9 spleen: 8.8 Cell line enhanced HEL: 26.9;HL-60: 5.6;U-698: 5.8;U-937: 4.3 +ZNF451 COASTER, dJ417I1.1, KIAA0576, KIAA1702 ENSG00000112200 Zinc finger protein 451 6 57086844-57170307 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028838 Approved Nucleus Expressed in all Expressed in all testis: 51.2 Expressed in all +BAG2 ENSG00000112208 BCL2 associated athanogene 2 6 57172326-57189833 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018862, HPA019918 Enhanced Supported Nucleoplasm Liver cancer:6.72e-6 (unfavourable), Thyroid cancer:1.26e-4 (unfavourable) Expressed in all Tissue enhanced smooth muscle: 42.0 endometrium: 37.5 Mixed +RAB23 ENSG00000112210 RAB23, member RAS oncogene family 6 57186992-57222314 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029135, HPA029136 Enhanced Enhanced Plasma membrane
Cytosol Expressed in all Mixed smooth muscle: 110.0 Expressed in all +TSPO2 BZRPL1, dJ34B21.2 ENSG00000112212 Translocator protein 2 6 41042554-41044337 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA066996 Uncertain Mixed Tissue enriched 17 bone marrow: 30.8 placenta: 1.8 Cell line enhanced CACO-2: 1.3 +FHL5 ACT, dJ393D12.2, FLJ33049 ENSG00000112214 Four and a half LIM domains 5 6 96562548-96616636 Predicted intracellular proteins Evidence at protein level Glioma:3.18e-4 (favourable) Mixed Tissue enhanced testis: 106.4 cervix, uterine: 43.3 Cell line enriched 9 ASC diff: 3.4 +GPR63 PSP24(beta), PSP24B ENSG00000112218 G protein-coupled receptor 63 6 96794126-96837463 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA039103 Approved Approved Nucleus
Plasma membrane
Cytosol Mixed Mixed testis: 4.6 Cell line enhanced HHSteC: 11.3;Karpas-707: 15.0 +KHDRBS2 MGC26664, SLM-1, SLM1 ENSG00000112232 KH RNA binding domain containing, signal transduction associated 2 6 61679960-62286227 Predicted intracellular proteins Evidence at protein level HPA000500, HPA029392 Supported Tissue enhanced Tissue enhanced cerebral cortex: 6.6;lung: 5.6;thyroid gland: 11.0 spleen: 1.8 Cell line enhanced AF22: 7.2;NTERA-2: 1.9;THP-1: 1.0 +FBXL4 FBL4, FBL5 ENSG00000112234 F-box and leucine rich repeat protein 4 6 98868538-98948006 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029140, CAB033362 Approved Enhanced Nuclear speckles Expressed in all Expressed in all parathyroid gland: 25.3 Expressed in all +CCNC CycC ENSG00000112237 Cyclin C 6 99542380-99568973 Predicted intracellular proteins Evidence at protein level CAB010499, HPA069322 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:8.12e-4 (favourable) Expressed in all Expressed in all thyroid gland: 99.2 Expressed in all +PRDM13 ENSG00000112238 PR/SET domain 13 6 99606730-99615578 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA070592 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +E2F3 ENSG00000112242 E2F transcription factor 3 6 20401906-20493715 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029779, HPA065012 Supported Nucleoplasm
Nuclear speckles
Cytosol Renal cancer:1.63e-8 (unfavourable), Ovarian cancer:1.69e-4 (favourable) Expressed in all Mixed thyroid gland: 14.4 Expressed in all +PTP4A1 PRL-1, PTPCAAX1 ENSG00000112245 Protein tyrosine phosphatase type IVA, member 1 6 63521748-63583587 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003281 Approved Cervical cancer:5.53e-4 (unfavourable) Expressed in all Expressed in all liver: 354.5 Expressed in all +SIM1 bHLHe14 ENSG00000112246 Single-minded family bHLH transcription factor 1 6 100385015-100464929 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA024385 Approved Nuclear speckles Renal cancer:5.32e-7 (favourable) Tissue enhanced Tissue enhanced epididymis: 3.5;kidney: 11.2;seminal vesicle: 3.2 skeletal muscle: 1.2 Cell line enhanced BJ: 13.9;BJ hTERT+: 19.3;RPTEC TERT1: 13.9 +ASCC3 ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH ENSG00000112249 Activating signal cointegrator 1 complex subunit 3 6 100508194-100881372 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031608, HPA031609, HPA031610 Enhanced Supported Golgi apparatus
Cytosol Expressed in all Expressed in all parathyroid gland: 26.5 Expressed in all +HDGFL1 dJ309H15.1, PWWP1 ENSG00000112273 Hepatoma derived growth factor-like 1 6 22569493-22571666 Predicted intracellular proteins Evidence at protein level HPA045679, HPA063707 Enhanced Tissue enriched Tissue enriched 1395 testis: 139.4 all non-specific tissues: 0.0 Cell line enriched 8 K-562: 1.0 +BVES HBVES, POP1, POPDC1 ENSG00000112276 Blood vessel epicardial substance 6 105096822-105137174 Disease related genes, Predicted membrane proteins Evidence at protein level HPA014788, HPA018176 Enhanced Supported Plasma membrane
Cell Junctions Mixed Tissue enhanced smooth muscle: 25.0 testis: 20.7 Cell line enhanced RH-30: 28.7;WM-115: 29.8 +COL9A1 ENSG00000112280 Collagen type IX alpha 1 chain 6 70215061-70303083 Disease related genes, Predicted secreted proteins Evidence at protein level HPA074749 Supported Mixed Tissue enriched 6 prostate: 31.4 testis: 5.1 Group enriched 6 AF22: 27.0;NTERA-2: 9.9 +MED23 CRSP130, CRSP3, DRIP130, Sur2 ENSG00000112282 Mediator complex subunit 23 6 131573966-131628229 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA070341 Approved Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 32.2 Expressed in all +WASF1 KIAA0269, SCAR1, WAVE, WAVE1 ENSG00000112290 WAS protein family member 1 6 110099819-110180004 Predicted intracellular proteins Evidence at protein level HPA004105, CAB022161 Approved Approved Liver cancer:2.82e-8 (unfavourable), Renal cancer:2.79e-5 (unfavourable) Expressed in all Group enriched 5 cerebral cortex: 138.9;testis: 149.9 ovary: 27.8 Mixed +GPLD1 ENSG00000112293 Glycosylphosphatidylinositol specific phospholipase D1 6 24424565-24495205 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB008625, HPA012500 Uncertain Liver cancer:1.12e-4 (favourable) Tissue enriched Tissue enhanced liver: 23.6 skin: 9.0 Cell line enhanced Daudi: 5.7;U-698: 5.6 +ALDH5A1 SSADH, SSDH ENSG00000112294 Aldehyde dehydrogenase 5 family member A1 6 24494852-24537207 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029715, HPA029716 Enhanced Enhanced Mitochondria Liver cancer:7.61e-6 (favourable), Renal cancer:3.68e-4 (favourable), Ovarian cancer:6.20e-4 (favourable) Expressed in all Expressed in all liver: 46.8 Cell line enhanced Daudi: 88.4;U-698: 105.9 +AIM1 CRYBG1, ST4 ENSG00000112297 Absent in melanoma 1 6 106360808-106571978 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB026378, HPA030948, HPA030949 Approved Approved Nucleus
Microtubules
Cytosol Expressed in all Tissue enhanced placenta: 107.4 esophagus: 71.3 Mixed +VNN1 Tiff66 ENSG00000112299 Vanin 1 6 132681590-132714049 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA064145 Approved Renal cancer:2.52e-4 (unfavourable) Tissue enhanced Group enriched 5 duodenum: 171.4;gallbladder: 174.7;liver: 142.4;small intestine: 106.3 kidney: 27.5 Cell line enhanced EFO-21: 10.3 +VNN2 FOAP-4, GPI-80 ENSG00000112303 Vanin 2 6 132743870-132763459 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Renal cancer:2.72e-7 (unfavourable) Mixed Tissue enhanced spleen: 76.9 lymph node: 45.0 Cell line enriched 6 Daudi: 40.8 +ACOT13 HT012, THEM2 ENSG00000112304 Acyl-CoA thioesterase 13 6 24667035-24705065 Predicted intracellular proteins Evidence at protein level HPA019881 Approved Approved Cell Junctions Ovarian cancer:2.53e-6 (favourable) Expressed in all Expressed in all kidney: 19.9 Expressed in all +SMAP1 FLJ13159, SMAP-1 ENSG00000112305 Small ArfGAP 1 6 70667776-70862015 Predicted intracellular proteins Evidence at protein level HPA030574 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 51.5 Expressed in all +RPS12 S12 ENSG00000112306 Ribosomal protein S12 6 132814441-132817564 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA006124, HPA006365 Approved Supported Golgi apparatus
Vesicles
Cytosol Renal cancer:1.06e-4 (unfavourable) Expressed in all Expressed in all ovary: 3959.0 Expressed in all +C6orf62 DKFZP564G182, FLJ12619, XTP12 ENSG00000112308 Chromosome 6 open reading frame 62 6 24704861-24720836 Predicted intracellular proteins Evidence at protein level HPA030564, HPA030566 Enhanced Approved Cytosol Urothelial cancer:3.62e-6 (favourable), Liver cancer:5.77e-5 (unfavourable), Ovarian cancer:4.04e-4 (favourable) Expressed in all Expressed in all testis: 174.4 Expressed in all +B3GAT2 GlcAT-S ENSG00000112309 Beta-1,3-glucuronyltransferase 2 6 70856679-70957038 Enzymes, Predicted membrane proteins Evidence at protein level HPA012059 Uncertain Group enriched Tissue enriched 10 cerebral cortex: 19.5 testis: 1.8 Cell line enriched 25 SCLC-21H: 25.9 +GMNN Gem ENSG00000112312 Geminin, DNA replication inhibitor 6 24774931-24786099 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB011458, CAB047327, CAB047328, HPA049977, HPA054597 Enhanced Enhanced Nucleoplasm Renal cancer:7.82e-5 (unfavourable), Ovarian cancer:4.13e-4 (favourable), Pancreatic cancer:9.77e-4 (unfavourable) Expressed in all Expressed in all prostate,testis: 67.7 Expressed in all +EYA4 CMD1J, DFNA10 ENSG00000112319 EYA transcriptional coactivator and phosphatase 4 6 133240598-133532120 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004805, HPA038771, HPA038772 Enhanced Approved Nucleoplasm Mixed Tissue enhanced seminal vesicle: 16.0 fallopian tube: 11.5 Cell line enhanced A549: 22.1;HeLa: 45.5;RH-30: 22.5;U-87 MG: 23.4 +SOBP FLJ10159 ENSG00000112320 Sine oculis binding protein homolog 6 107489958-107660167 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029242 Uncertain Approved Nucleoplasm
Vesicles Pancreatic cancer:1.55e-5 (favourable) Expressed in all Tissue enhanced cerebral cortex: 26.4 ovary: 13.7 Cell line enhanced AF22: 12.5;AN3-CA: 15.3 +NR2E1 TLL, TLX, XTLL ENSG00000112333 Nuclear receptor subfamily 2 group E member 1 6 108166058-108188809 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036954, HPA055642 Enhanced Approved Nuclear bodies Tissue enriched Tissue enriched 46 cerebral cortex: 11.4 adrenal gland: 0.2 Cell line enhanced BEWO: 2.9;U-251 MG: 3.3 +SNX3 Grd19 ENSG00000112335 Sorting nexin 3 6 108211222-108261260 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Breast cancer:4.37e-5 (unfavourable), Renal cancer:2.30e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 288.7 Expressed in all +SLC17A2 NPT3 ENSG00000112337 Solute carrier family 17 member 2 6 25912754-25930726 Predicted membrane proteins, Transporters Evidence at protein level HPA038270 Uncertain Liver cancer:8.54e-4 (favourable) Tissue enriched Tissue enriched 85 liver: 40.8 kidney,testis: 0.4 Cell line enriched 12 Hep G2: 2.5 +HBS1L DKFZp434g247, EF-1a, eRF3c, ERFS, HBS1, HSPC276, KIAA1038 ENSG00000112339 HBS1 like translational GTPase 6 134960378-135103056 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029728, HPA029729 Approved Approved Nuclear bodies
Cytosol Colorectal cancer:6.77e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 73.2 Expressed in all +TRIM38 RNF15, RORET ENSG00000112343 Tripartite motif containing 38 6 25962802-25991226 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031685 Approved Approved Plasma membrane
Cell Junctions
Centrosome Urothelial cancer:4.94e-9 (favourable), Thyroid cancer:8.20e-5 (favourable), Ovarian cancer:8.95e-5 (favourable) Expressed in all Mixed spleen: 19.7 Mixed +PEX7 PTS2R, RD ENSG00000112357 Peroxisomal biogenesis factor 7 6 136822564-136913937 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA049202 Uncertain Supported Nucleoplasm
Vesicles Renal cancer:1.85e-10 (favourable), Colorectal cancer:1.61e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 25.3 Mixed +ZBTB24 BIF1, KIAA0441, PATZ2, ZNF450 ENSG00000112365 Zinc finger and BTB domain containing 24 6 109462594-109483237 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA017872, HPA049003 Uncertain Approved Nucleus
Cytokinetic bridge
Centrosome Liver cancer:3.15e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 13.9 Expressed in all +FIG4 ALS11, CMT4J, dJ249I4.1, hSac3, KIAA0274, SAC3 ENSG00000112367 FIG4 phosphoinositide 5-phosphatase 6 109691312-109825428 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017823, HPA068859 Approved Approved Vesicles
Lipid droplets Liver cancer:4.73e-4 (unfavourable), Breast cancer:5.91e-4 (unfavourable), Renal cancer:8.19e-4 (favourable), Colorectal cancer:8.42e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 33.1 Expressed in all +PERP dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW ENSG00000112378 PERP, TP53 apoptosis effector 6 138088505-138107511 Predicted membrane proteins Evidence at protein level HPA022269 Enhanced Pancreatic cancer:1.05e-5 (unfavourable), Lung cancer:3.73e-4 (unfavourable), Breast cancer:5.46e-4 (unfavourable) Expressed in all Group enriched 6 esophagus: 571.9;skin: 1235.5 breast: 151.1 Cell line enhanced hTCEpi: 661.0 +ARFGEF3 BIG3, C6orf92, dJ171N11.1, KIAA1244, PPP1R33 ENSG00000112379 ARFGEF family member 3 6 138161921-138344663 Predicted intracellular proteins Evidence at protein level HPA036350 Uncertain Breast cancer:8.20e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 23.7;parathyroid gland: 29.7 prostate: 19.2 Cell line enhanced RH-30: 13.0;RT4: 15.4;SK-BR-3: 16.6 +SLC16A10 MCT10, TAT1 ENSG00000112394 Solute carrier family 16 member 10 6 111087503-111231194 Predicted membrane proteins, Transporters Evidence at protein level HPA016860 Approved Approved Vesicles
Cell Junctions Tissue enriched Tissue enhanced placenta: 38.6 skin: 22.4 Cell line enhanced HAP1: 53.9;HEK 293: 20.6;RPMI-8226: 30.8 +HECA dJ225E12.1, HDC, HDCL, hHDC ENSG00000112406 Hdc homolog, cell cycle regulator 6 139135112-139180802 Predicted intracellular proteins Evidence at protein level HPA042313 Uncertain Renal cancer:8.09e-4 (unfavourable) Expressed in all Expressed in all spleen: 38.1 Mixed +ADGRG6 FLJ14937, GPR126 ENSG00000112414 Adhesion G protein-coupled receptor G6 6 142301854-142446266 Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017346 Approved Pancreatic cancer:2.78e-5 (unfavourable), Lung cancer:8.78e-4 (unfavourable) Mixed Tissue enhanced placenta: 67.2 liver: 36.9 Cell line enhanced HUVEC TERT2: 133.3;MCF7: 118.0 +PHACTR2 C6orf56, KIAA0680 ENSG00000112419 Phosphatase and actin regulator 2 6 143536845-143831185 Predicted intracellular proteins Evidence at protein level HPA031719, HPA031720, HPA031725 Approved Renal cancer:1.99e-4 (favourable) Expressed in all Expressed in all placenta: 120.1 Cell line enhanced TIME: 66.9 +EPM2A LD, LDE ENSG00000112425 EPM2A, laforin glucan phosphatase 6 145382535-145736023 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA053643, HPA055468 Enhanced Nucleoplasm Renal cancer:4.08e-7 (favourable) Expressed in all Mixed skeletal muscle: 26.8 Mixed +OR12D3 hs6M1-27 ENSG00000112462 Olfactory receptor family 12 subfamily D member 3 6 29373423-29375291 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +SLC39A7 D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7 ENSG00000112473 Solute carrier family 39 member 7 6 33200445-33204439 Predicted membrane proteins, Transporters Evidence at protein level HPA053999 Approved Supported Endoplasmic reticulum Liver cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 41.1 Expressed in all +CCR6 BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22 ENSG00000112486 C-C motif chemokine receptor 6 6 167111807-167139696 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB006820, HPA014488 Approved Not detected Tissue enhanced lymph node: 20.4;tonsil: 32.4 spleen: 17.0 Cell line enriched 7 Hep G2: 6.2 +UNC93A dJ366N23.1, dJ366N23.2 ENSG00000112494 Unc-93 homolog A (C. elegans) 6 167271169-167316019 Predicted membrane proteins Evidence at protein level HPA035729 Uncertain Tissue enhanced Tissue enhanced duodenum: 9.7;liver: 7.1;skin: 17.8 esophagus: 5.6 Group enriched 9 CACO-2: 6.1;Hep G2: 2.1;SCLC-21H: 3.7 +SLC22A2 OCT2 ENSG00000112499 Solute carrier family 22 member 2 6 160171061-160277638 Predicted membrane proteins, Transporters Evidence at protein level HPA008567, CAB068236, CAB068237 Enhanced Renal cancer:1.85e-7 (favourable) Tissue enriched Tissue enriched 83 kidney: 150.3 seminal vesicle: 1.8 Not detected +PHF1 MTF2L2, PCL1, TDRD19C ENSG00000112511 PHD finger protein 1 6 33410399-33416453 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031038 Approved Approved Nucleoplasm Colorectal cancer:9.64e-5 (unfavourable), Urothelial cancer:1.72e-4 (favourable) Expressed in all Mixed testis: 16.0 Mixed +CUTA ACHAP, C6orf82 ENSG00000112514 CutA divalent cation tolerance homolog 6 33416442-33418317 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016787, HPA064369 Uncertain Approved Plasma membrane
Focal adhesion sites Lung cancer:8.50e-4 (favourable) Expressed in all Expressed in all thyroid gland: 293.5 Expressed in all +PACRG FLJ32724, Glup, HAK005771, PARK2CRG ENSG00000112530 PARK2 coregulated 6 162727132-163315492 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066293 Enhanced Renal cancer:2.55e-6 (favourable) Mixed Tissue enhanced fallopian tube: 57.1;testis: 53.0 cerebral cortex,epididymis: 11.8 Cell line enhanced SCLC-21H: 8.2 +QKI QK3 ENSG00000112531 QKI, KH domain containing RNA binding 6 163414000-163578596 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA019123, CAB022602 Enhanced Supported Supported Nucleoplasm Renal cancer:2.31e-5 (unfavourable), Liver cancer:1.27e-4 (unfavourable), Stomach cancer:3.69e-4 (unfavourable) Tissue enriched Expressed in all cerebral cortex: 359.6 Expressed in all +C6orf118 bA85G2.1, MGC23884 ENSG00000112539 Chromosome 6 open reading frame 118 6 165279664-165309607 Predicted intracellular proteins Evidence at transcript level HPA029787, HPA029789 Approved Uncertain Mitochondria Tissue enhanced Group enriched 6 fallopian tube: 26.2;testis: 12.8 lung: 3.2 Cell line enhanced AF22: 2.7;SCLC-21H: 1.8 +PDE10A ENSG00000112541 Phosphodiesterase 10A 6 165327287-165986603 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB045998, HPA047200 Supported Renal cancer:4.44e-7 (unfavourable) Mixed Tissue enhanced thyroid gland: 14.5 testis: 12.2 Cell line enhanced LHCN-M2: 14.4;SH-SY5Y: 11.1;TIME: 14.8 +MDFI I-mfa ENSG00000112559 MyoD family inhibitor 6 41636882-41654246 Predicted intracellular proteins Evidence at protein level HPA049973 Approved Approved Nucleoplasm Renal cancer:2.85e-6 (unfavourable), Lung cancer:1.32e-5 (unfavourable), Melanoma:9.11e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 35.9 gallbladder: 19.7 Cell line enhanced BEWO: 88.8;HBEC3-KT: 83.8;REH: 287.1 +TFEB bHLHe35, TCFEB ENSG00000112561 Transcription factor EB 6 41683978-41736259 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049532 Supported Nucleoplasm Renal cancer:1.06e-5 (favourable), Pancreatic cancer:4.77e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 54.3 Cell line enhanced BEWO: 65.1;U-698: 44.9 +SMOC2 SMAP2 ENSG00000112562 SPARC related modular calcium binding 2 6 168441151-168673445 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB033979 Uncertain Renal cancer:1.16e-6 (unfavourable) Expressed in all Mixed endometrium: 183.6 Cell line enhanced AF22: 8.0;EFO-21: 2.6;RPMI-8226: 7.7;RPTEC TERT1: 2.8 +CCND3 ENSG00000112576 Cyclin D3 6 41934933-42050357 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB000116 Approved Thyroid cancer:8.08e-6 (favourable) Expressed in all Expressed in all lymph node: 159.2 Expressed in all +BYSL ENSG00000112578 Bystin like 6 41921188-41933046 Predicted intracellular proteins Evidence at protein level HPA031217, HPA031219 Enhanced Enhanced Nucleus
Nucleoli Renal cancer:2.15e-8 (unfavourable), Liver cancer:6.43e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 11.7 Expressed in all +FAM120B CCPG, KIAA1838, PGCC1 ENSG00000112584 Family with sequence similarity 120B 6 170290703-170407065 Predicted intracellular proteins Evidence at protein level HPA037518, HPA037519 Uncertain Approved Nucleoplasm
Cytosol Ovarian cancer:1.60e-4 (unfavourable), Pancreatic cancer:2.70e-4 (favourable) Expressed in all Expressed in all fallopian tube: 16.5 Expressed in all +TBP GTF2D1, SCA17, TFIID ENSG00000112592 TATA-box binding protein 6 170554302-170572870 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009442, HPA049805 Approved Supported Nucleoplasm Liver cancer:1.51e-7 (unfavourable) Expressed in all Expressed in all testis: 61.8 Expressed in all +GUCA1B GCAP2, RP48 ENSG00000112599 Guanylate cyclase activator 1B 6 42184401-42194916 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055479 Supported Mixed Mixed skin: 4.2 Mixed +PRPH2 CACD2, rd2, RDS, RP7, TSPAN22 ENSG00000112619 Peripherin 2 6 42696600-42722574 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA029458 Supported Mixed Mixed parathyroid gland: 8.6 Cell line enhanced ASC TERT1: 2.4;fHDF/TERT166: 4.1;HHSteC: 6.6;HSkMC: 4.4;LHCN-M2: 3.0 +GLTSCR1L KIAA0240 ENSG00000112624 GLTSCR1 like 6 42746958-42868560 Predicted intracellular proteins Evidence at protein level HPA029390, HPA029391 Approved Supported Nucleoplasm Head and neck cancer:5.47e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.9 Expressed in all +PPP2R5D B56D ENSG00000112640 Protein phosphatase 2 regulatory subunit B'delta 6 42984499-43012342 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029045, HPA029046 Approved Approved Nucleoplasm
Cytosol Liver cancer:3.89e-4 (unfavourable) Expressed in all Expressed in all testis: 43.3 Expressed in all +MRPL2 CGI-22, MRP-L14, RPML14 ENSG00000112651 Mitochondrial ribosomal protein L2 6 43054029-43059806 Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA007455, HPA064814 Approved Approved Nucleoplasm
Mitochondria Ovarian cancer:6.01e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 33.3 Expressed in all +PTK7 CCK4 ENSG00000112655 Protein tyrosine kinase 7 (inactive) 6 43076268-43161719 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003222 Approved Expressed in all Mixed endometrium: 117.3 Mixed +SRF MCM1 ENSG00000112658 Serum response factor 6 43171299-43181507 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001819, CAB005416 Supported Supported Nucleus Renal cancer:2.01e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 70.2 Expressed in all +CUL9 H7AP1, KIAA0708, PARC ENSG00000112659 Cullin 9 6 43182175-43224587 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016434, HPA052004 Approved Approved Cytosol Head and neck cancer:2.37e-5 (favourable), Colorectal cancer:2.48e-4 (unfavourable), Urothelial cancer:4.87e-4 (favourable), Breast cancer:5.28e-4 (favourable), Pancreatic cancer:8.07e-4 (favourable) Expressed in all Mixed testis: 10.0 Mixed +DNPH1 C6orf108, dJ330M21.3, rcl ENSG00000112667 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 6 43225629-43229484 Predicted intracellular proteins Evidence at protein level HPA029675, HPA029676 Enhanced Approved Nucleoplasm
Cytosol Expressed in all Expressed in all duodenum: 104.2 Expressed in all +DUSP22 JKAP, JSP1, MKPX, VHX ENSG00000112679 Dual specificity phosphatase 22 6 291630-351355 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031394 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 85.1 Expressed in all +EXOC2 FLJ11026, SEC5L1, Sec5p ENSG00000112685 Exocyst complex component 2 6 485133-693111 Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level HPA032093 Supported Vesicles Expressed in all Expressed in all testis: 30.4 Expressed in all +COX7A2 COX7AL, COXVIIa-L ENSG00000112695 Cytochrome c oxidase subunit 7A2 6 75237675-75250323 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:3.43e-5 (favourable) Expressed in all Expressed in all testis: 641.4 Expressed in all +TMEM30A C6orf67, CDC50A, FLJ10856 ENSG00000112697 Transmembrane protein 30A 6 75252924-75284968 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014561 Approved Supported Mitochondria Expressed in all Expressed in all parathyroid gland: 167.6 Expressed in all +GMDS GMD, SDR3E1 ENSG00000112699 GDP-mannose 4,6-dehydratase 6 1623806-2245692 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031528 Enhanced Endometrial cancer:5.89e-4 (favourable), Renal cancer:5.93e-4 (favourable) Expressed in all Mixed duodenum: 106.3 Expressed in all +SENP6 KIAA0797, SUSP1 ENSG00000112701 SUMO1/sentrin specific peptidase 6 6 75601509-75718278 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024376 Approved Supported Nucleoplasm
Cytosol Thyroid cancer:2.83e-5 (unfavourable), Renal cancer:6.09e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 75.2 Expressed in all +IMPG1 GP147, IPM150, SPACR ENSG00000112706 Interphotoreceptor matrix proteoglycan 1 6 75921115-76072678 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027142, HPA030332, HPA030333 Enhanced Not detected Tissue enhanced cerebral cortex: 1.5;skin: 1.6 duodenum,small intestine: 0.9 Cell line enhanced HaCaT: 1.0 +VEGFA VEGF, VEGF-A, VPF ENSG00000112715 Vascular endothelial growth factor A 6 43770184-43786487 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB005429, CAB039240, HPA069116, CAB069907 Supported Renal cancer:1.76e-5 (unfavourable), Liver cancer:2.34e-5 (unfavourable), Endometrial cancer:2.10e-4 (unfavourable), Urothelial cancer:2.73e-4 (favourable), Cervical cancer:4.50e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 452.5 Expressed in all +PRPF4B KIAA0536, PR4H, Prp4 ENSG00000112739 Pre-mRNA processing factor 4B 6 4021267-4064983 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020638 Approved Supported Nuclear speckles Urothelial cancer:6.82e-5 (favourable), Liver cancer:2.27e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 37.7 Expressed in all +TTK CT96, MPH1, MPS1, MPS1L1 ENSG00000112742 TTK protein kinase 6 80003887-80042527 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010166, CAB013229 Enhanced Approved Nucleoli
Cytosol Liver cancer:3.84e-10 (unfavourable), Endometrial cancer:1.44e-5 (unfavourable), Pancreatic cancer:2.54e-4 (unfavourable) Mixed Tissue enhanced testis: 60.8 bone marrow: 15.5 Mixed +SLC29A1 ENT1 ENSG00000112759 Solute carrier family 29 member 1 (Augustine blood group) 6 44219505-44234151 Predicted membrane proteins, Transporters Evidence at protein level HPA012384 Approved Renal cancer:2.96e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 124.4 Expressed in all +WISP3 CCN6 ENSG00000112761 WNT1 inducible signaling pathway protein 3 6 112054072-112070969 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA062438, HPA078340 Approved Endoplasmic reticulum Mixed Tissue enhanced epididymis: 3.0;skin: 2.0 fallopian tube: 1.8 Cell line enhanced RT4: 4.6;THP-1: 1.2;U-2197: 1.2 +BTN2A1 BT2.1, BTF1, BTN2.1 ENSG00000112763 Butyrophilin subfamily 2 member A1 6 26457904-26476621 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019208 Approved Approved Plasma membrane Urothelial cancer:4.52e-5 (favourable), Renal cancer:5.90e-5 (unfavourable) Expressed in all Expressed in all placenta: 26.3 Expressed in all +LAMA4 LAMA3 ENSG00000112769 Laminin subunit alpha 4 6 112108760-112254939 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA015693, CAB078156 Enhanced Approved Plasma membrane
Cytosol Renal cancer:2.00e-4 (unfavourable) Expressed in all Mixed smooth muscle: 146.3 Cell line enhanced ASC diff: 216.1;ASC TERT1: 333.0;HSkMC: 271.2;HUVEC TERT2: 340.0;TIME: 306.5 +FAM46A C6orf37, FLJ20037 ENSG00000112773 Family with sequence similarity 46 member A 6 81491439-81752774 Predicted intracellular proteins Evidence at protein level HPA051067, HPA067140 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.07e-5 (unfavourable) Expressed in all Tissue enhanced bone marrow: 143.7 gallbladder: 51.5 Cell line enhanced HL-60: 75.4;THP-1: 108.4 +CLIC5 DFNB102 ENSG00000112782 Chloride intracellular channel 5 6 45898451-46080395 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA074371 Supported Nuclear speckles
Plasma membrane Tissue enhanced Tissue enhanced lung: 116.1;skeletal muscle: 119.2 heart muscle: 76.0 Group enriched 7 CAPAN-2: 13.3;EFO-21: 10.0;HDLM-2: 5.7;REH: 13.6;U-266/70: 10.5 +FBRSL1 KIAA1545 ENSG00000112787 Fibrosin like 1 12 132489551-132585188 Predicted intracellular proteins Evidence at protein level HPA049880 Approved Approved Nucleus
Plasma membrane
Cytosol Renal cancer:1.17e-4 (favourable), Urothelial cancer:7.21e-4 (favourable), Prostate cancer:9.82e-4 (unfavourable) Expressed in all Expressed in all spleen: 16.9 Expressed in all +ENPP5 ENSG00000112796 Ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 6 46159187-46170971 Predicted membrane proteins Evidence at protein level HPA016902 Enhanced Renal cancer:4.44e-13 (favourable), Pancreatic cancer:4.04e-4 (favourable), Lung cancer:4.57e-4 (favourable) Expressed in all Tissue enhanced epididymis: 296.6 thyroid gland: 85.6 Cell line enhanced CAPAN-2: 9.8;SCLC-21H: 5.6;T-47d: 8.1;U-266/84: 5.5 +LY86 dJ80N2.1, MD-1 ENSG00000112799 Lymphocyte antigen 86 6 6588108-6654983 Predicted secreted proteins Evidence at protein level CAB025000, HPA044895 Approved Testis cancer:5.61e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 82.3 spleen: 66.3 Cell line enhanced Daudi: 51.2;RPMI-8226: 162.0;THP-1: 62.7;U-937: 34.1 +PRSS16 TSSP ENSG00000112812 Protease, serine 16 6 27247701-27256624 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA017743 Uncertain Ovarian cancer:6.46e-5 (favourable) Mixed Tissue enhanced thyroid gland: 22.0 epididymis: 16.5 Cell line enhanced hTCEpi: 14.7;RPMI-8226: 7.9 +MEP1A PPHA ENSG00000112818 Meprin A subunit alpha 6 46793390-46839782 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB025163, HPA029416 Enhanced Tissue enriched Group enriched 42 colon: 117.8;duodenum: 282.2;rectum: 114.3;small intestine: 538.5 appendix: 6.2 Cell line enhanced BEWO: 1.2;CACO-2: 2.4;RPMI-8226: 1.0 +TBX18 ENSG00000112837 T-box 18 6 84687351-84764519 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Mixed adipose tissue: 6.1 Cell line enhanced A549: 52.2 +ERBIN ERBB2IP, LAP2 ENSG00000112851 Erbb2 interacting protein 5 65926475-66082549 Predicted intracellular proteins Evidence at protein level HPA048606, HPA059863 Approved Supported Nuclear speckles
Plasma membrane Expressed in all Expressed in all testis: 50.1 Expressed in all +PCDHB2 PCDH-BETA2 ENSG00000112852 Protocadherin beta 2 5 141094578-141098703 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007548 Enhanced Approved Nucleoplasm Urothelial cancer:4.84e-4 (unfavourable), Renal cancer:6.99e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 7.7 testis: 7.5 Cell line enhanced AF22: 23.3;AN3-CA: 47.2;EFO-21: 26.8 +HARS2 HARSL, HARSR, HO3 ENSG00000112855 Histidyl-tRNA synthetase 2, mitochondrial 5 140691426-140699291 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA035941 Approved Approved Cytosol Liver cancer:2.92e-4 (unfavourable), Colorectal cancer:6.19e-4 (favourable), Breast cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.5 Expressed in all +NUDT12 DKFZP761I172 ENSG00000112874 Nudix hydrolase 12 5 103548855-103562793 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045449 Supported Renal cancer:2.86e-5 (favourable) Expressed in all Mixed parathyroid gland: 45.1 Mixed +CEP72 FLJ10565, KIAA1519 ENSG00000112877 Centrosomal protein 72 5 612272-667168 Predicted intracellular proteins Evidence at protein level HPA058235, HPA074879 Approved Supported Centrosome Endometrial cancer:2.90e-4 (unfavourable) Expressed in all Tissue enhanced testis: 10.4 ovary: 3.3 Cell line enhanced HDLM-2: 41.0 +MAN2A1 GOLIM7, MANA2 ENSG00000112893 Mannosidase alpha class 2A member 1 5 109689366-109869625 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB022377, HPA026896 Enhanced Supported Golgi apparatus Expressed in all Expressed in all parathyroid gland: 40.5 Expressed in all +SEMA5A SEMAF, semF ENSG00000112902 Semaphorin 5A 5 9035026-9546075 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004632 Approved Renal cancer:3.66e-8 (favourable), Head and neck cancer:2.45e-4 (favourable) Expressed in all Mixed cervix, uterine: 19.3 Cell line enhanced BJ hTERT+: 52.1;fHDF/TERT166: 29.1;RT4: 54.3 +C7 ENSG00000112936 Complement C7 5 40909252-40982939 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001465 Approved Liver cancer:5.89e-4 (favourable) Expressed in all Tissue enhanced adrenal gland: 1115.3 placenta: 718.4 Group enriched 11 ASC diff: 115.0;HHSteC: 185.4;HSkMC: 221.4;SH-SY5Y: 223.2 +PAPD7 LAK-1, POLK, POLS, TRF4, TRF4-1 ENSG00000112941 Poly(A) RNA polymerase D7, non-canonical 5 6713007-6757048 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045487, HPA046742 Enhanced Supported Nucleoplasm
Nuclear membrane
Golgi apparatus Renal cancer:7.99e-5 (unfavourable), Urothelial cancer:8.55e-4 (favourable) Expressed in all Expressed in all testis: 19.1 Expressed in all +GHR GHBP ENSG00000112964 Growth hormone receptor 5 42423777-42721878 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA045339, HPA057705 Enhanced Supported Plasma membrane
Cytosol
Cytoplasmic bodies Liver cancer:2.73e-6 (favourable) Mixed Group enriched 6 adipose tissue: 91.4;liver: 110.5 prostate: 18.0 Group enriched 7 HSkMC: 15.4;T-47d: 52.5 +HMGCS1 HMGCS ENSG00000112972 3-hydroxy-3-methylglutaryl-CoA synthase 1 5 43289395-43313512 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032907, HPA036913, HPA036914 Approved Supported Nucleus
Plasma membrane
Cytosol Renal cancer:3.87e-6 (favourable) Expressed in all Expressed in all liver: 208.7 Expressed in all +DAP ENSG00000112977 Death associated protein 5 10679230-10761272 Predicted intracellular proteins Evidence at protein level HPA029456 Uncertain Approved Nucleoplasm
Vesicles
Mitochondria Liver cancer:2.15e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 156.6 Expressed in all +NME5 nm23-H5, RSPH23 ENSG00000112981 NME/NM23 family member 5 5 138115172-138139443 Predicted intracellular proteins Evidence at protein level HPA035648, HPA044555 Approved Approved Nucleoplasm
Nuclear bodies Endometrial cancer:7.24e-5 (favourable), Renal cancer:1.76e-4 (favourable) Mixed Tissue enhanced fallopian tube: 59.4;testis: 95.0 epididymis: 28.2 Cell line enhanced RPTEC TERT1: 22.4;SCLC-21H: 8.0;U-87 MG: 5.4 +BRD8 p120, SMAP ENSG00000112983 Bromodomain containing 8 5 138139766-138178986 Predicted intracellular proteins Evidence at protein level HPA001841 Supported Approved Nucleoplasm
Mitochondria Liver cancer:1.09e-6 (unfavourable), Renal cancer:7.80e-4 (unfavourable) Expressed in all Expressed in all testis: 148.4 Expressed in all +KIF20A RAB6KIFL ENSG00000112984 Kinesin family member 20A 5 138178719-138187715 Predicted intracellular proteins Evidence at protein level HPA036909, HPA036910 Approved Supported Nucleoplasm
Cytokinetic bridge
Cleavage furrow Renal cancer:0.00e+0 (unfavourable), Liver cancer:2.14e-12 (unfavourable), Pancreatic cancer:1.90e-4 (unfavourable), Lung cancer:6.79e-4 (unfavourable) Expressed in all Tissue enhanced testis: 20.2 tonsil: 11.5 Mixed +NNT ENSG00000112992 Nicotinamide nucleotide transhydrogenase 5 43602692-43707405 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004829, CAB004975 Enhanced Enhanced Mitochondria Renal cancer:1.22e-15 (favourable) Expressed in all Expressed in all heart muscle: 130.6 Expressed in all +MRPS30 PAP, PDCD9 ENSG00000112996 Mitochondrial ribosomal protein S30 5 44808925-44820428 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA018686, HPA021149 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:2.87e-9 (favourable), Liver cancer:5.91e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 19.5 Expressed in all +HSPA9 GRP75, HSPA9B, mot-2, mthsp75, PBP74 ENSG00000113013 Heat shock protein family A (Hsp70) member 9 5 138554882-138575444 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000898, CAB005219 Enhanced Enhanced Mitochondria Breast cancer:2.93e-4 (unfavourable), Colorectal cancer:4.53e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 263.5 Expressed in all +MRPS27 KIAA0264 ENSG00000113048 Mitochondrial ribosomal protein S27 5 72219409-72320646 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA071751 Approved Expressed in all Expressed in all thyroid gland: 59.5 Expressed in all +PFDN1 PFD1 ENSG00000113068 Prefoldin subunit 1 5 140245039-140303121 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006499 Approved Approved Nucleoli
Plasma membrane
Cytosol Liver cancer:8.81e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 106.3 Expressed in all +HBEGF DTR, DTS, HEGFL ENSG00000113070 Heparin binding EGF like growth factor 5 140332843-140346631 Predicted membrane proteins Evidence at protein level HPA053243 Uncertain Head and neck cancer:2.41e-4 (unfavourable), Prostate cancer:6.00e-4 (favourable), Pancreatic cancer:7.09e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 89.0 Cell line enhanced U-698: 63.3 +SLC4A9 AE4 ENSG00000113073 Solute carrier family 4 member 9 5 140360202-140375143 Plasma proteins, Predicted membrane proteins, Transporters Evidence at transcript level HPA051307 Uncertain Tissue enriched Tissue enriched 19 kidney: 12.2 seminal vesicle,testis: 0.6 Not detected +LOX ENSG00000113083 Lysyl oxidase 5 122063195-122078360 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA043930 Supported Endoplasmic reticulum Renal cancer:3.93e-8 (unfavourable), Urothelial cancer:3.32e-4 (unfavourable), Liver cancer:7.38e-4 (unfavourable) Expressed in all Mixed adipose tissue: 29.6 Cell line enhanced BJ: 799.4;fHDF/TERT166: 1126.5;U-138 MG: 458.1 +GZMK PRSS, TRYP2 ENSG00000113088 Granzyme K 5 55024253-55034570 Enzymes, Predicted secreted proteins Evidence at protein level HPA063181 Enhanced Renal cancer:1.06e-4 (unfavourable), Breast cancer:8.68e-4 (favourable) Expressed in all Tissue enhanced lymph node: 103.9 spleen: 41.9 Not detected +CDH9 ENSG00000113100 Cadherin 9 5 26880600-27121150 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007167 Approved Not detected Tissue enhanced cerebral cortex: 11.4;kidney: 6.5 testis: 4.3 Cell line enhanced K-562: 6.6;NTERA-2: 10.2 +APBB3 FE65L2 ENSG00000113108 Amyloid beta precursor protein binding family B member 3 5 140558268-140564781 Predicted intracellular proteins Evidence at protein level HPA005571 Uncertain Supported Actin filaments
Cytosol Renal cancer:2.06e-6 (unfavourable), Pancreatic cancer:6.79e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 11.5 testis: 6.6 Cell line enhanced SCLC-21H: 7.1 +TMCO6 FLJ39769, PRO1580 ENSG00000113119 Transmembrane and coiled-coil domains 6 5 140639427-140645408 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037473, HPA037474 Uncertain Approved Nucleoplasm
Mitochondria Renal cancer:6.37e-4 (unfavourable) Expressed in all Mixed testis: 13.6 Mixed +SPARC ON ENSG00000113140 Secreted protein acidic and cysteine rich 5 151661096-151687165 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002306, HPA002989, HPA003020 Supported Renal cancer:3.53e-5 (unfavourable) Expressed in all Expressed in all placenta: 3240.9 Cell line enhanced ASC diff: 3432.3;BJ: 3597.1;fHDF/TERT166: 5254.9;WM-115: 4850.9 +IK RED, RER ENSG00000113141 IK cytokine, down-regulator of HLA II 5 140647058-140662479 Predicted intracellular proteins Evidence at protein level HPA048798 Supported Enhanced Nuclear speckles Liver cancer:2.32e-7 (unfavourable), Cervical cancer:1.29e-4 (favourable) Expressed in all Expressed in all fallopian tube: 230.6 Expressed in all +HMGCR ENSG00000113161 3-hydroxy-3-methylglutaryl-CoA reductase 5 75336329-75362104 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA008338, CAB016797 Approved Renal cancer:9.42e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 87.5 Expressed in all +COL4A3BP CERT, GPBP, STARD11 ENSG00000113163 Collagen type IV alpha 3 binding protein 5 75368486-75512138 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035645, HPA042608 Uncertain Enhanced Nucleoplasm
Golgi apparatus Renal cancer:1.24e-5 (favourable) Expressed in all Expressed in all thyroid gland: 70.6 Expressed in all +FAF2 ETEA, KIAA0887, UBXD8, UBXN3B ENSG00000113194 Fas associated factor family member 2 5 176447628-176510074 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA065968, HPA071246, HPA073828 Approved Enhanced Endoplasmic reticulum
Lipid droplets Lung cancer:1.38e-4 (unfavourable), Liver cancer:1.79e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.0 Expressed in all +HAND1 bHLHa27, eHand, Hxt, Thing1 ENSG00000113196 Heart and neural crest derivatives expressed 1 5 154474972-154478264 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA040925 Approved Uncertain Nucleus
Nuclear membrane Group enriched Tissue enhanced smooth muscle: 16.8 adrenal gland: 6.2 Cell line enriched 8 SH-SY5Y: 123.7 +PCDHB3 PCDH-BETA3 ENSG00000113205 Protocadherin beta 3 5 141100473-141103827 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050296 Uncertain Supported Vesicles Mixed Tissue enhanced testis: 6.9 endometrium,prostate: 2.4 Cell line enhanced EFO-21: 10.7;SH-SY5Y: 16.1;U-138 MG: 5.2 +PCDHB5 DKFZp586B0217, PCDH-BETA5 ENSG00000113209 Protocadherin beta 5 5 141135218-141138625 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA013191 Approved Mixed Mixed ovary: 7.3 Cell line enhanced AF22: 18.5;NTERA-2: 17.7;SCLC-21H: 19.4;T-47d: 16.6;U-138 MG: 32.0;U-2 OS: 15.2 +PCDHB6 PCDH-BETA6 ENSG00000113211 Protocadherin beta 6 5 141150022-141153287 Predicted membrane proteins Evidence at transcript level HPA029566 Uncertain Uncertain Nucleus
Plasma membrane
Cytosol Renal cancer:5.52e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 7.1 testis: 3.5 Cell line enhanced EFO-21: 15.4;SH-SY5Y: 7.4;T-47d: 5.0;U-2197: 7.0;WM-115: 10.2 +PCDHB7 PCDH-BETA7 ENSG00000113212 Protocadherin beta 7 5 141172619-141176383 Plasma proteins, Predicted membrane proteins Evidence at transcript level HPA059271 Approved Tissue enhanced Tissue enhanced endometrium: 6.6 smooth muscle: 4.5 Cell line enhanced EFO-21: 4.4;U-138 MG: 3.1;U-2197: 8.8;U-87 MG: 3.2;WM-115: 3.2 +PDE8B ENSG00000113231 Phosphodiesterase 8B 5 77210449-77429807 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036911, HPA036912 Enhanced Approved Nucleoplasm
Cytosol Tissue enriched Tissue enriched 6 thyroid gland: 293.7 cerebral cortex: 53.0 Cell line enhanced BJ hTERT+: 14.6;HeLa: 32.2;SK-BR-3: 10.4 +CLK4 ENSG00000113240 CDC like kinase 4 5 178602664-178630615 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043746 Approved Approved Actin filaments Expressed in all Expressed in all testis: 22.5 Expressed in all +PCDHB15 PCDH-BETA15 ENSG00000113248 Protocadherin beta 15 5 141245349-141249365 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007172, CAB026471, HPA074676 Uncertain Approved Mitochondria Mixed Mixed cerebral cortex: 12.7 Cell line enhanced AF22: 5.7;LHCN-M2: 4.0;WM-115: 4.7 +HAVCR1 CD365, HAVCR, HAVCR-1, KIM1, TIM-1, TIM1, TIMD1 ENSG00000113249 Hepatitis A virus cellular receptor 1 5 157029413-157059119 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007173, CAB075697 Approved Approved Vesicles Urothelial cancer:1.32e-4 (favourable), Stomach cancer:7.81e-4 (unfavourable) Tissue enriched Group enriched 6 colon: 4.8;kidney: 8.3;rectum: 4.1;testis: 1.7 gallbladder: 0.8 Group enriched 5 A549: 86.4;CACO-2: 95.7;RPTEC TERT1: 33.8 +GRM6 CSNB1B, GPRC1F, mGlu6, MGLUR6 ENSG00000113262 Glutamate metabotropic receptor 6 5 178978327-178996206 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA014511 Supported Not detected Not detected testis: 0.7 Not detected +ITK EMT, LYK, PSCTK2 ENSG00000113263 IL2 inducible T-cell kinase 5 157142933-157255191 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced appendix: 20.2;lymph node: 33.2;tonsil: 22.3 spleen: 14.0 Cell line enhanced HDLM-2: 3.2;HEL: 3.4;HMC-1: 3.8;MOLT-4: 18.7 +RNF130 G1RZFP, GOLIATH, GP ENSG00000113269 Ring finger protein 130 5 179911651-180072118 Enzymes, Predicted membrane proteins Evidence at protein level HPA014499 Approved Cervical cancer:6.32e-4 (favourable) Expressed in all Expressed in all adipose tissue: 74.8 Mixed +THG1L FLJ11601, FLJ20546, hTHG1, ICF45, IHG-1 ENSG00000113272 TRNA-histidine guanylyltransferase 1 like 5 157731197-157741448 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035877, HPA035878 Approved Renal cancer:3.93e-6 (unfavourable) Expressed in all Mixed endometrium: 10.3 Expressed in all +ARSB ENSG00000113273 Arylsulfatase B 5 78777209-78986087 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA037770, HPA037771 Enhanced Approved Golgi apparatus Urothelial cancer:3.42e-4 (unfavourable) Expressed in all Mixed smooth muscle: 18.2 Expressed in all +CLINT1 CLINT, ENTH, EPNR, KIAA0171 ENSG00000113282 Clathrin interactor 1 5 157785743-157859175 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043280, HPA056947 Supported Supported Nucleoplasm
Vesicles Renal cancer:8.88e-5 (favourable), Colorectal cancer:2.95e-4 (favourable), Thyroid cancer:6.77e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 171.0 Expressed in all +THBS4 ENSG00000113296 Thrombospondin 4 5 79991311-80083287 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB004597, HPA042426 Approved Approved Vesicles Urothelial cancer:3.33e-4 (unfavourable) Expressed in all Group enriched 6 adipose tissue: 234.3;heart muscle: 113.6;smooth muscle: 388.9 thyroid gland: 44.6 Cell line enhanced AF22: 3.1;SCLC-21H: 2.9;THP-1: 4.7;U-2 OS: 3.0 +CNOT6 CCR4, Ccr4a, KIAA1194 ENSG00000113300 CCR4-NOT transcription complex subunit 6 5 180494412-180578405 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044568 Approved Approved Cytosol Liver cancer:3.61e-7 (unfavourable) Expressed in all Expressed in all testis: 25.1 Expressed in all +IL12B CLMF, CLMF2, IL-12B, NKSF, NKSF2 ENSG00000113302 Interleukin 12B 5 159314783-159330887 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA040970 Approved Tissue enriched Not detected spleen: 0.6 Cell line enhanced SCLC-21H: 1.0 +BTNL8 BTN9.2, FLJ21458 ENSG00000113303 Butyrophilin like 8 5 180899077-180950906 Predicted membrane proteins Evidence at protein level HPA039738 Approved Group enriched Group enriched 6 colon: 26.1;duodenum: 117.4;rectum: 27.7;small intestine: 94.2 gallbladder: 10.4 Cell line enriched 26 CACO-2: 31.4 +TTC1 TPR1 ENSG00000113312 Tetratricopeptide repeat domain 1 5 160009113-160065543 Predicted intracellular proteins Evidence at protein level HPA036557, HPA057502 Approved Enhanced Cytosol Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 80.4 Expressed in all +MSH3 DUP, MRP1 ENSG00000113318 MutS homolog 3 5 80654648-80876460 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA036081 Approved Nuclear bodies Colorectal cancer:5.90e-5 (favourable), Renal cancer:1.77e-4 (favourable) Expressed in all Expressed in all thyroid gland: 18.6 Expressed in all +RASGRF2 GRF2, Ras-GRF2 ENSG00000113319 Ras protein specific guanine nucleotide releasing factor 2 5 80960672-81230156 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA018679 Uncertain Supported Endoplasmic reticulum Mixed Tissue enhanced cerebral cortex: 25.5 ovary: 22.8 Cell line enhanced BEWO: 37.2;CACO-2: 19.9;Hep G2: 21.9;HHSteC: 17.6 +GABRG2 ENSG00000113327 Gamma-aminobutyric acid type A receptor gamma2 subunit 5 162000057-162162977 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB079060 Supported Tissue enhanced Tissue enriched 12 cerebral cortex: 66.5 adrenal gland: 5.3 Cell line enhanced CACO-2: 11.6;U-266/70: 17.2;U-266/84: 13.6 +CCNG1 CCNG ENSG00000113328 Cyclin G1 5 163437569-163446151 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000350 Supported Supported Nucleoplasm Colorectal cancer:7.00e-4 (favourable) Expressed in all Expressed in all duodenum: 137.7 Mixed +POLR3G RPC32, RPC7 ENSG00000113356 RNA polymerase III subunit G 5 90471748-90514553 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level CAB010109, HPA052658 Enhanced Approved Nucleoplasm
Cytosol Mixed Mixed parathyroid gland: 10.7 Expressed in all +DROSHA Etohi2, HSA242976, RN3, RNASE3L, RNASEN ENSG00000113360 Drosha ribonuclease III 5 31400497-31532196 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Liver cancer:1.39e-4 (unfavourable), Endometrial cancer:6.79e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.5 Expressed in all +CDH6 ENSG00000113361 Cadherin 6 5 31193750-31329146 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA007047, HPA007456, CAB025274 Enhanced Group enriched Tissue enhanced kidney: 16.0 gallbladder: 14.7 Cell line enriched 7 EFO-21: 458.4 +LMNB1 ENSG00000113368 Lamin B1 5 126776623-126837020 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005269, HPA050524, HPA053579 Supported Enhanced Nuclear membrane Renal cancer:3.33e-16 (unfavourable), Liver cancer:3.08e-6 (unfavourable) Expressed in all Tissue enhanced lymph node: 41.4 appendix: 36.2 Mixed +ARRDC3 KIAA1376, TLIMP ENSG00000113369 Arrestin domain containing 3 5 91368724-91383359 Predicted intracellular proteins Evidence at protein level Renal cancer:4.25e-8 (unfavourable), Stomach cancer:2.26e-4 (unfavourable), Ovarian cancer:3.30e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 143.0 Expressed in all +GOLPH3 GOPP1, GPP34, MIDAS, Vps74 ENSG00000113384 Golgi phosphoprotein 3 5 32124704-32174350 Predicted intracellular proteins Evidence at protein level HPA044564, HPA055841 Approved Supported Golgi apparatus
Vesicles Expressed in all Expressed in all gallbladder: 120.5 Expressed in all +SUB1 p14, p15, PC4 ENSG00000113387 SUB1 homolog, transcriptional regulator 5 32531633-32604079 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001311, CAB015351 Supported Supported Nucleus
Nucleoli Liver cancer:5.25e-6 (unfavourable), Melanoma:2.79e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 234.5 Expressed in all +NPR3 ANPRC, C5orf23, FLJ14054, GUCY2B, NPRC ENSG00000113389 Natriuretic peptide receptor 3 5 32689070-32791724 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052702 Supported Approved Cytosol Renal cancer:5.43e-6 (favourable) Tissue enhanced Tissue enriched 5 kidney: 114.1 adipose tissue: 21.9 Cell line enhanced ASC TERT1: 24.8;HeLa: 53.7;HSkMC: 36.4;U-138 MG: 21.1 +FAM172A C5orf21, DKFZP564D172 ENSG00000113391 Family with sequence similarity 172 member A 5 93618069-94111699 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012299, HPA045505 Approved Supported Nucleoplasm
Cytosol Renal cancer:4.43e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 27.0 Expressed in all +SLC27A6 ACSVL2, FACVL2, FATP6, VLCS-H1 ENSG00000113396 Solute carrier family 27 member 6 5 128538013-129033642 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA008987 Approved Approved Nuclear bodies Tissue enriched Tissue enhanced adrenal gland: 32.6;fallopian tube: 34.0 testis: 24.3 Cell line enriched 9 BEWO: 42.4 +TARS ENSG00000113407 Threonyl-tRNA synthetase 5 33440696-33469539 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037425 Approved Supported Actin filaments
Cytosol Liver cancer:9.88e-7 (unfavourable), Breast cancer:6.14e-5 (unfavourable), Endometrial cancer:5.17e-4 (unfavourable), Renal cancer:9.63e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 44.3 Expressed in all +IRX4 ENSG00000113430 Iroquois homeobox 4 5 1877413-1887236 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA064094 Uncertain Nucleus
Vesicles Mixed Tissue enhanced prostate: 5.8;skin: 6.9 esophagus: 1.4 Cell line enhanced BEWO: 43.3;HaCaT: 15.1;HBEC3-KT: 6.7 +LNPEP CAP, IRAP, P-LAP, PLAP ENSG00000113441 Leucyl and cystinyl aminopeptidase 5 96935394-97037515 Enzymes, Predicted membrane proteins Evidence at protein level HPA043642 Approved Expressed in all Mixed parathyroid gland: 23.3 Expressed in all +PDE4D DPDE3 ENSG00000113448 Phosphodiesterase 4D 5 58969038-60522120 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA045895 Approved Approved Nuclear membrane
Plasma membrane
Cytosol Renal cancer:4.00e-5 (favourable) Mixed Mixed bone marrow: 47.7 Cell line enhanced A549: 56.1;AN3-CA: 65.2;HeLa: 68.4 +RAD1 HRAD1, REC1 ENSG00000113456 RAD1 checkpoint DNA exonuclease 5 34905264-34918989 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006692 Approved Supported Nucleoplasm
Vesicles Liver cancer:1.06e-5 (unfavourable), Breast cancer:6.30e-4 (unfavourable) Expressed in all Mixed testis: 11.9 Expressed in all +BRIX1 BRIX, BXDC2, FLJ11100 ENSG00000113460 BRX1, biogenesis of ribosomes 5 34915376-34925996 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039614 Approved Enhanced Nucleoli Renal cancer:3.07e-9 (unfavourable), Liver cancer:4.11e-8 (unfavourable), Endometrial cancer:1.10e-5 (unfavourable), Breast cancer:2.18e-4 (unfavourable), Ovarian cancer:6.34e-4 (favourable) Expressed in all Expressed in all placenta: 27.6 Expressed in all +AGXT2 AGT2 ENSG00000113492 Alanine--glyoxylate aminotransferase 2 5 34998101-35048135 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037382 Enhanced Renal cancer:7.47e-4 (favourable) Group enriched Group enriched 33 kidney: 197.9;liver: 59.3 small intestine: 3.9 Not detected +PRLR ENSG00000113494 Prolactin receptor 5 35048756-35230589 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enhanced placenta: 70.9 kidney: 33.1 Cell line enriched 22 T-47d: 356.8 +SLC12A7 DKFZP434F076, KCC4 ENSG00000113504 Solute carrier family 12 member 7 5 1050376-1112035 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041652 Approved Uncertain Cytosol Liver cancer:2.12e-6 (unfavourable), Urothelial cancer:3.16e-5 (favourable) Expressed in all Mixed duodenum: 24.3 Cell line enhanced REH: 40.1 +IL4 BCGF-1, BCGF1, BSF1, IL-4, MGC79402 ENSG00000113520 Interleukin 4 5 132673986-132682676 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA072995 Approved Not detected Tissue enhanced parathyroid gland: 1.6 skin: 0.6 Group enriched 6 HMC-1: 3.4;MOLT-4: 17.0 +RAD50 hRad50, RAD50-2 ENSG00000113522 RAD50 double strand break repair protein 5 132556019-132646344 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022103, CAB024979, HPA052291 Enhanced Enhanced Nucleoplasm Renal cancer:1.95e-4 (favourable), Cervical cancer:3.77e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 14.6 Expressed in all +IL5 EDF, IL-5, TRF ENSG00000113525 Interleukin 5 5 132541444-132556838 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010304 Approved Not detected Tissue enriched 9 testis: 9.6 small intestine: 1.0 Cell line enhanced Hep G2: 1.9;TIME: 1.0 +ST8SIA4 PST, PST1, SIAT8D ENSG00000113532 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 5 100806935-100903266 Predicted secreted proteins Evidence at protein level HPA051126, HPA053995 Approved Approved Golgi apparatus Renal cancer:7.80e-7 (unfavourable) Expressed in all Mixed appendix: 19.3 Cell line enhanced AF22: 40.7;HDLM-2: 64.4;Karpas-707: 41.2;RPMI-8226: 30.6 +GNPDA1 GNPDA, GNPI, GPI, HLN, KIAA0060 ENSG00000113552 Glucosamine-6-phosphate deaminase 1 5 141991749-142013041 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000499, HPA046891 Uncertain Approved Golgi apparatus
Vesicles Liver cancer:2.60e-6 (unfavourable) Expressed in all Expressed in all kidney: 77.6 Mixed +PCDH12 VE-cadherin-2 ENSG00000113555 Protocadherin 12 5 141943585-141969741 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA051242 Uncertain Renal cancer:2.56e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 38.5 spleen: 22.5 Cell line enhanced HUVEC TERT2: 19.4;Karpas-707: 41.2;U-937: 7.5 +SKP1 EMC19, MGC34403, OCP-II, OCP2, p19A, SKP1A, TCEB1L ENSG00000113558 S-phase kinase associated protein 1 5 134148935-134177038 Predicted intracellular proteins Evidence at protein level CAB012982, HPA053745, HPA058134 Approved Supported Nucleus
Cytosol Renal cancer:5.20e-4 (favourable), Liver cancer:5.72e-4 (unfavourable), Breast cancer:7.53e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 934.2 Expressed in all +NUP155 KIAA0791, N155 ENSG00000113569 Nucleoporin 155 5 37288137-37371181 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA037775 Enhanced Enhanced Nuclear membrane Liver cancer:1.35e-6 (unfavourable) Expressed in all Tissue enriched 9 testis: 126.8 parathyroid gland: 14.4 Expressed in all +PPP2CA PP2AC, PP2Calpha ENSG00000113575 Protein phosphatase 2 catalytic subunit alpha 5 134194334-134226142 Enzymes, Predicted intracellular proteins Evidence at protein level CAB003848, HPA043236 Approved Liver cancer:7.33e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 126.6 Expressed in all +FGF1 AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1 ENSG00000113578 Fibroblast growth factor 1 5 142592178-142698070 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA003265, CAB017519 Enhanced Renal cancer:2.59e-5 (favourable), Thyroid cancer:3.45e-5 (favourable) Tissue enriched Tissue enhanced cerebral cortex: 129.9;kidney: 59.4 heart muscle: 32.8 Cell line enhanced BJ: 37.6;BJ hTERT+ SV40 Large T+: 33.4;BJ hTERT+ SV40 Large T+ RasG12V: 43.9;HBF TERT88: 62.3;hTEC/SVTERT24-B: 45.5;U-2 OS: 33.6 +NR3C1 GR, GRL ENSG00000113580 Nuclear receptor subfamily 3 group C member 1 5 143277931-143435512 Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004248, CAB010435 Supported Enhanced Nucleoplasm
Mitochondria
Cytosol Renal cancer:1.72e-6 (unfavourable), Endometrial cancer:3.64e-5 (unfavourable) Expressed in all Expressed in all placenta: 67.0 Mixed +C5orf15 HTGN29, KCT2 ENSG00000113583 Chromosome 5 open reading frame 15 5 133955502-133968787 Predicted membrane proteins Evidence at protein level HPA011951, HPA039165 Uncertain Approved Golgi apparatus Expressed in all Expressed in all thyroid gland: 81.7 Expressed in all +PPWD1 KIAA0073 ENSG00000113593 Peptidylprolyl isomerase domain and WD repeat containing 1 5 65563236-65587549 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019353, HPA019360 Enhanced Supported Nuclear bodies Liver cancer:2.19e-4 (unfavourable), Renal cancer:6.72e-4 (unfavourable) Expressed in all Expressed in all lymph node: 31.6 Expressed in all +LIFR CD118 ENSG00000113594 Leukemia inhibitory factor receptor alpha 5 38474963-38608354 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004478, CAB010252 Approved Approved Nuclear speckles
Golgi apparatus Renal cancer:1.40e-7 (favourable), Lung cancer:1.92e-4 (favourable) Mixed Mixed thyroid gland: 68.0 Cell line enhanced AF22: 93.6;SCLC-21H: 72.8 +TRIM23 ARD1, ARFD1, RNF46 ENSG00000113595 Tripartite motif containing 23 5 65589680-65625975 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA039605 Approved Expressed in all Expressed in all cerebral cortex: 46.9 Expressed in all +TRAPPC13 C5orf44, FLJ13611, FLJ26957, MGC48585 ENSG00000113597 Trafficking protein particle complex 13 5 65624716-65666233 Predicted intracellular proteins Evidence at protein level HPA037777 Approved Approved Nucleus
Plasma membrane Renal cancer:8.66e-4 (favourable) Expressed in all Expressed in all prostate: 29.8 Expressed in all +C9 ENSG00000113600 Complement C9 5 39284262-39424868 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB002151, HPA029577 Uncertain Uncertain Plasma membrane
Cytosol Tissue enriched Tissue enriched 120 liver: 728.9 epididymis: 6.0 Cell line enhanced U-698: 1.4 +SEC24A ENSG00000113615 SEC24 homolog A, COPII coat complex component 5 134648789-134727823 Predicted intracellular proteins Evidence at protein level HPA038901, HPA056825 Approved Approved Nucleoli fibrillar center
Vesicles Cervical cancer:3.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.8 Expressed in all +TXNDC15 2310047H23Rik, C5orf14, FLJ22625 ENSG00000113621 Thioredoxin domain containing 15 5 134873803-134901525 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015483 Approved Approved Golgi apparatus Renal cancer:1.44e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 85.3 Expressed in all +TTC33 OSRF ENSG00000113638 Tetratricopeptide repeat domain 33 5 40512333-40755975 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038252, HPA038253 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:1.83e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 25.6 Expressed in all +RARS DALRD1 ENSG00000113643 Arginyl-tRNA synthetase 5 168486445-168519299 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003979, HPA004130 Approved Enhanced Nucleoplasm
Cytosol Liver cancer:1.10e-8 (unfavourable), Head and neck cancer:7.59e-5 (unfavourable) Expressed in all Expressed in all duodenum: 54.4 Expressed in all +WWC1 KIAA0869, KIBRA, PPP1R168 ENSG00000113645 WW and C2 domain containing 1 5 168291651-168472303 Predicted intracellular proteins Evidence at protein level HPA038016, HPA038017 Approved Approved Golgi apparatus Renal cancer:1.95e-8 (favourable) Expressed in all Mixed salivary gland: 61.5 Cell line enhanced RPTEC TERT1: 195.6 +H2AFY macroH2A1.2 ENSG00000113648 H2A histone family member Y 5 135333900-135399914 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041189, HPA050962 Supported Supported Nucleus Liver cancer:2.89e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 155.6 Expressed in all +TCERG1 CA150, TAF2S, Urn1 ENSG00000113649 Transcription elongation regulator 1 5 146447311-146511961 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064854, HPA069752, HPA069808 Enhanced Enhanced Nucleoplasm Renal cancer:4.70e-11 (unfavourable), Liver cancer:5.34e-5 (unfavourable) Expressed in all Expressed in all lymph node: 20.7 Expressed in all +DPYSL3 CRMP4, DRP-3, ULIP ENSG00000113657 Dihydropyrimidinase like 3 5 147390811-147510056 Predicted intracellular proteins Evidence at protein level HPA010948 Approved Supported Cytosol Renal cancer:3.87e-9 (unfavourable), Urothelial cancer:8.23e-4 (unfavourable) Expressed in all Tissue enhanced smooth muscle: 310.0 seminal vesicle: 223.4 Cell line enhanced SH-SY5Y: 728.5 +SMAD5 Dwfc, JV5-1, MADH5 ENSG00000113658 SMAD family member 5 5 136132845-136188747 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058931 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all endometrium: 43.1 Expressed in all +CSNK1A1 CK1, CK1a, CK1alpha, CKIa, CKIalpha ENSG00000113712 Casein kinase 1 alpha 1 5 149492197-149551552 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016680, HPA051334 Uncertain Approved Cytosol Colorectal cancer:1.15e-4 (favourable), Pancreatic cancer:5.79e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 219.6 Expressed in all +HMGXB3 HMGX3, KIAA0194, SMF ENSG00000113716 HMG-box containing 3 5 150000046-150053142 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005967 Approved Nucleoli Liver cancer:3.37e-5 (unfavourable) Expressed in all Tissue enriched 10 parathyroid gland: 283.3 prostate: 27.4 Expressed in all +ERGIC1 ERGIC-32, ERGIC32, KIAA1181, NET24 ENSG00000113719 Endoplasmic reticulum-golgi intermediate compartment 1 5 172834275-172952685 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018666, HPA018900 Enhanced Enhanced Nucleoplasm
Vesicles Expressed in all Expressed in all prostate: 238.2 Expressed in all +PDGFRB CD140b, JTK12, PDGFR, PDGFR1 ENSG00000113721 Platelet derived growth factor receptor beta 5 150113837-150155872 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB003842, CAB018144, HPA028499 Enhanced Supported Golgi apparatus
Vesicles Renal cancer:5.87e-8 (unfavourable), Urothelial cancer:8.11e-4 (unfavourable) Expressed in all Mixed gallbladder: 193.8 Cell line enhanced ASC diff: 923.6;ASC TERT1: 324.4 +CDX1 ENSG00000113722 Caudal type homeobox 1 5 150166795-150184558 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055196 Enhanced Tissue enhanced Group enriched 9 colon: 129.9;duodenum: 64.5;rectum: 134.7;small intestine: 104.9 appendix: 12.1 Cell line enhanced BJ hTERT+: 5.4;SH-SY5Y: 1.3 +ATP6V0E1 ATP6H, ATP6V0E, M9.2 ENSG00000113732 ATPase H+ transporting V0 subunit e1 5 172983757-173035445 Predicted membrane proteins Evidence at transcript level Expressed in all Expressed in all epididymis: 772.1 Expressed in all +BNIP1 Nip1, SEC20 ENSG00000113734 BCL2 interacting protein 1 5 173144442-173164387 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008009, HPA008149 Enhanced Supported Endoplasmic reticulum Expressed in all Expressed in all testis: 27.0 Expressed in all +STC2 STC-2 ENSG00000113739 Stanniocalcin 2 5 173314713-173329503 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045372 Uncertain Approved Endoplasmic reticulum Renal cancer:4.17e-8 (unfavourable), Head and neck cancer:1.76e-6 (unfavourable), Liver cancer:3.07e-5 (unfavourable), Breast cancer:7.40e-5 (favourable), Stomach cancer:7.57e-4 (unfavourable) Tissue enriched Tissue enhanced breast: 164.6 placenta: 33.2 Cell line enhanced LHCN-M2: 707.5;T-47d: 753.9;U-138 MG: 321.3 +CPEB4 KIAA1673 ENSG00000113742 Cytoplasmic polyadenylation element binding protein 4 5 173888280-173961976 Predicted intracellular proteins Evidence at protein level HPA038394 Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:4.99e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 119.8 Cell line enhanced U-266/70: 86.1;U-266/84: 121.7 +HRH2 ENSG00000113749 Histamine receptor H2 5 175658030-175710756 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013770 Approved Tissue enhanced Tissue enhanced bone marrow: 23.5 appendix: 16.7 Cell line enhanced RPMI-8226: 45.4;SK-MEL-30: 15.0;THP-1: 12.1;U-937: 16.9 +DBN1 D0S117E ENSG00000113758 Drebrin 1 5 177456608-177474401 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051452, HPA056940 Enhanced Supported Plasma membrane
Actin filaments Renal cancer:8.28e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 82.9 Mixed +ZNF346 JAZ, Zfp346 ENSG00000113761 Zinc finger protein 346 5 177022696-177081189 Predicted intracellular proteins Evidence at protein level HPA018485 Approved Enhanced Nucleus Liver cancer:1.88e-7 (unfavourable), Endometrial cancer:9.54e-5 (unfavourable), Pancreatic cancer:1.20e-4 (favourable) Expressed in all Expressed in all thyroid gland: 18.0 Expressed in all +UNC5A KIAA1976, UNC5H1 ENSG00000113763 Unc-5 netrin receptor A 5 176810477-176880895 Predicted membrane proteins Evidence at protein level HPA071450 Approved Plasma membrane
Cytosol Endometrial cancer:2.23e-4 (unfavourable) Tissue enhanced Group enriched 22 adrenal gland: 10.3;cerebral cortex: 35.4 lymph node: 1.0 Cell line enriched 14 SCLC-21H: 104.8 +EHHADH ECHD ENSG00000113790 Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase 3 185190624-185281990 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036401, HPA042021 Enhanced Renal cancer:1.28e-5 (favourable) Group enriched Group enriched 7 kidney: 148.6;liver: 173.1 duodenum: 21.4 Mixed +CNTN3 BIG-1, PANG ENSG00000113805 Contactin 3 3 74262568-74521140 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA003341 Approved Mixed Tissue enhanced cerebral cortex: 12.4 fallopian tube: 12.0 Cell line enhanced BJ: 6.0;fHDF/TERT166: 15.2 +SMC4 CAP-C, hCAP-C, SMC4L1 ENSG00000113810 Structural maintenance of chromosomes 4 3 160399274-160434962 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029449, CAB055509 Approved Supported Nuclear speckles
Cytosol Renal cancer:8.05e-7 (unfavourable), Pancreatic cancer:4.20e-5 (unfavourable), Liver cancer:2.94e-4 (unfavourable), Endometrial cancer:7.63e-4 (unfavourable), Prostate cancer:9.00e-4 (unfavourable) Expressed in all Mixed testis: 54.9 Expressed in all +SELENOK SELK ENSG00000113811 Selenoprotein K 3 53884410-53891988 Predicted membrane proteins Evidence at protein level HPA008196 Uncertain Approved Nucleoplasm
Cytosol Lung cancer:3.76e-4 (favourable), Endometrial cancer:7.18e-4 (favourable) Expressed in all Expressed in all epididymis: 75.4 Expressed in all +ACTR8 INO80N ENSG00000113812 ARP8 actin-related protein 8 homolog 3 53867066-53882202 Predicted intracellular proteins Evidence at protein level HPA065236 Supported Nucleus
Centrosome Renal cancer:7.88e-9 (favourable), Liver cancer:5.11e-6 (unfavourable), Colorectal cancer:2.21e-4 (favourable) Expressed in all Expressed in all testis: 39.5 Expressed in all +TBCCD1 FLJ10560 ENSG00000113838 TBCC domain containing 1 3 186546073-186570543 Predicted intracellular proteins Evidence at protein level Liver cancer:1.87e-4 (unfavourable) Expressed in all Expressed in all testis: 35.5 Expressed in all +TIMMDC1 C3orf1, FLJ22597 ENSG00000113845 Translocase of inner mitochondrial membrane domain containing 1 3 119498532-119525090 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA053214, HPA055846 Uncertain Enhanced Nucleus
Mitochondria Liver cancer:1.12e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 31.5 Expressed in all +CRBN MRT2, MRT2A ENSG00000113851 Cereblon 3 3144628-3179727 Disease related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA045910 Approved Approved Nucleoli Expressed in all Expressed in all testis: 87.7 Expressed in all +KNG1 BDK, BK, KNG ENSG00000113889 Kininogen 1 3 186717276-186743954 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001616, HPA001645, CAB009809 Enhanced Liver cancer:1.28e-6 (favourable) Tissue enriched Group enriched 994 kidney: 522.4;liver: 1864.6 rectum: 1.2 Cell line enhanced CACO-2: 1.5;Hep G2: 1.2;RH-30: 1.3 +HRG HPRG, HRGP ENSG00000113905 Histidine rich glycoprotein 3 186660216-186678240 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA050269, HPA054598 Supported Uncertain Nucleoli fibrillar center Liver cancer:9.64e-5 (favourable) Tissue enriched Tissue enriched 83 liver: 2689.0 kidney: 32.2 Cell line enhanced HL-60: 2.0;RH-30: 2.8;SiHa: 1.1 +BCL6 BCL5, BCL6A, LAZ3, ZBTB27, ZNF51 ENSG00000113916 B-cell CLL/lymphoma 6 3 187721377-187745727 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000307, HPA004899, HPA050645 Enhanced Enhanced Nucleoplasm
Golgi apparatus Renal cancer:1.27e-9 (unfavourable) Expressed in all Expressed in all adipose tissue: 113.5 Cell line enhanced Daudi: 112.8;U-698: 150.4 +HGD AKU, HGO ENSG00000113924 Homogentisate 1,2-dioxygenase 3 120628173-120682571 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA047374, HPA052359 Enhanced Supported Golgi apparatus Endometrial cancer:1.78e-4 (favourable) Tissue enhanced Tissue enhanced kidney: 175.8;liver: 324.3 gallbladder: 87.1 Group enriched 10 CACO-2: 38.8;EFO-21: 75.8;Hep G2: 110.3;RPTEC TERT1: 153.1 +CLDN16 HOMG3, PCLN1 ENSG00000113946 Claudin 16 3 190322541-190412143 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA056020 Enhanced Endometrial cancer:1.99e-5 (unfavourable) Group enriched Tissue enriched 6 kidney: 51.7 thyroid gland: 8.7 Group enriched 135 EFO-21: 435.6;RPTEC TERT1: 123.6 +ARL6 BBS3, RP55 ENSG00000113966 ADP ribosylation factor like GTPase 6 3 97764521-97801242 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019361 Approved Approved Nucleoplasm
Vesicles Renal cancer:2.53e-7 (favourable) Expressed in all Mixed parathyroid gland: 19.5 Cell line enhanced SCLC-21H: 28.0 +NPHP3 CFAP31, FLJ30691, FLJ36696, KIAA2000, MKS7, NPH3, SLSN3 ENSG00000113971 Nephrocystin 3 3 132680609-132722442 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA009150 Uncertain Renal cancer:8.28e-9 (unfavourable) Mixed Mixed endometrium: 16.5 Mixed +CD86 B7-2, B7.2, CD28LG2 ENSG00000114013 CD86 molecule 3 122055366-122121139 CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004319 Uncertain Renal cancer:9.83e-5 (unfavourable) Expressed in all Mixed appendix: 47.8 Cell line enriched 10 HDLM-2: 275.8 +AMOTL2 LCCP ENSG00000114019 Angiomotin like 2 3 134355874-134375479 Predicted intracellular proteins Evidence at protein level HPA063027 Approved Cell Junctions Endometrial cancer:1.94e-4 (unfavourable) Expressed in all Mixed adipose tissue: 76.7 Cell line enhanced BEWO: 266.7 +NIT2 ENSG00000114021 Nitrilase family member 2 3 100334701-100361635 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036999 Approved Supported Centrosome
Cytosol Endometrial cancer:4.62e-4 (unfavourable) Expressed in all Mixed kidney: 19.0 Expressed in all +FAM162A C3orf28, E2IG5 ENSG00000114023 Family with sequence similarity 162 member A 3 122384176-122412334 Predicted membrane proteins Evidence at protein level HPA035856, HPA058113 Approved Enhanced Mitochondria
Cytosol Urothelial cancer:3.93e-4 (favourable) Expressed in all Expressed in all rectum: 162.9 Expressed in all +OGG1 HMMH, HOGG1, MUTM, OGH1 ENSG00000114026 8-oxoguanine DNA glycosylase 3 9749944-9788219 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027514, CAB047301 Approved Enhanced Nucleoplasm Liver cancer:5.77e-5 (unfavourable), Renal cancer:2.65e-4 (favourable) Expressed in all Expressed in all lymph node: 30.5 Expressed in all +KPNA1 IPOA5, NPI-1, RCH2, SRP1 ENSG00000114030 Karyopherin subunit alpha 1 3 122421949-122514945 Predicted intracellular proteins, Transporters Evidence at protein level HPA053627, HPA063426 Enhanced Enhanced Nucleus
Cytosol Endometrial cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.3 Expressed in all +PCCB ENSG00000114054 Propionyl-CoA carboxylase beta subunit 3 136250306-136337896 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036939, HPA036940 Enhanced Renal cancer:6.47e-7 (favourable) Expressed in all Expressed in all liver: 103.1 Expressed in all +UBE3A ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A ENSG00000114062 Ubiquitin protein ligase E3A 15 25333728-25439056 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009723, HPA039410, HPA040380 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 86.1 Expressed in all +ARMC8 DKFZP434A043, GID5, HSPC056, VID28 ENSG00000114098 Armadillo repeat containing 8 3 138187248-138298389 Predicted intracellular proteins Evidence at protein level HPA036996, HPA044869 Approved Approved Nucleoplasm
Vesicles
Cytosol Liver cancer:8.90e-5 (unfavourable), Endometrial cancer:2.05e-4 (unfavourable), Prostate cancer:2.15e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 38.2 Expressed in all +CEP70 BITE, FLJ13036 ENSG00000114107 Centrosomal protein 70 3 138494344-138594538 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036941, HPA036942 Enhanced Uncertain Nucleoplasm
Cytosol Prostate cancer:9.60e-5 (unfavourable), Cervical cancer:2.93e-4 (favourable) Expressed in all Expressed in all testis: 123.8 Expressed in all +RBP2 CRABP-II, CRBP2, CRBPII, RBPC2 ENSG00000114113 Retinol binding protein 2 3 139452884-139480747 Predicted intracellular proteins, Transporters Evidence at protein level HPA035866 Enhanced Approved Golgi apparatus Tissue enhanced Group enriched 204 duodenum: 2746.0;small intestine: 2037.7 lung: 11.7 Cell line enriched 6 CACO-2: 65.5 +RBP1 CRABP-I, CRBP, CRBP1, CRBPI, RBPC ENSG00000114115 Retinol binding protein 1 3 139517434-139539829 Predicted intracellular proteins Evidence at protein level HPA007338, CAB018603, CAB019276 Enhanced Approved Nucleoplasm
Cytosol Expressed in all Tissue enhanced fallopian tube: 634.8;ovary: 1297.7 adrenal gland: 376.4 Cell line enriched 6 SH-SY5Y: 887.3 +SLC25A36 FLJ10618, PNC2 ENSG00000114120 Solute carrier family 25 member 36 3 140941830-140979933 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA027036 Approved Approved Nucleus
Mitochondria
Cytosol Urothelial cancer:1.55e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 69.5 Expressed in all +GRK7 GPRK7 ENSG00000114124 G protein-coupled receptor kinase 7 3 141778148-141818490 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Not detected skin,testis: 0.2 Not detected +RNF7 CKBBP1, ROC2, SAG ENSG00000114125 Ring finger protein 7 3 141738204-141747560 Predicted intracellular proteins Evidence at protein level HPA036995 Approved Supported Nucleoplasm Renal cancer:1.54e-9 (unfavourable), Liver cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all epididymis: 86.2 Expressed in all +TFDP2 Dp-2 ENSG00000114126 Transcription factor Dp-2 3 141944428-142149544 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB018396 Supported Supported Nucleus
Vesicles Cervical cancer:6.32e-4 (favourable), Renal cancer:9.84e-4 (favourable) Expressed in all Expressed in all testis: 127.5 Expressed in all +XRN1 SEP1 ENSG00000114127 5'-3' exoribonuclease 1 3 142306607-142448062 Predicted intracellular proteins Evidence at protein level HPA035005, HPA035006 Approved Supported Plasma membrane
Cytosol Pancreatic cancer:9.43e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.2 Cell line enriched 5 RH-30: 137.9 +KAT2B GCN5, GCN5L, P/CAF, PCAF ENSG00000114166 Lysine acetyltransferase 2B 3 20040023-20154404 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB004526, HPA055839 Supported Approved Nucleus Expressed in all Expressed in all parathyroid gland: 85.2 Mixed +BCHE CHE1, CHE2, E1 ENSG00000114200 Butyrylcholinesterase 3 165772904-165837472 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001560 Approved Head and neck cancer:1.06e-4 (unfavourable) Group enriched Tissue enhanced liver: 265.5 endometrium: 67.7 Cell line enriched 7 Karpas-707: 542.1 +SERPINI2 MEPI, PANCPIN, PI14, TSA2004 ENSG00000114204 Serpin family I member 2 3 167441789-167479004 Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 47 pancreas: 288.1 fallopian tube: 6.1 Group enriched 10 THP-1: 6.0;U-937: 1.2 +PDCD10 CCM3, TFAR15 ENSG00000114209 Programmed cell death 10 3 167683298-167734939 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027095 Approved Pancreatic cancer:5.22e-5 (unfavourable), Liver cancer:2.30e-4 (unfavourable), Head and neck cancer:3.89e-4 (unfavourable), Renal cancer:5.88e-4 (favourable), Endometrial cancer:9.34e-4 (unfavourable) Expressed in all Expressed in all testis: 80.8 Expressed in all +LRRC31 FLJ23259 ENSG00000114248 Leucine rich repeat containing 31 3 169839179-169869930 Predicted intracellular proteins Evidence at protein level HPA037548 Uncertain Mixed Group enriched 5 colon: 18.2;duodenum: 8.8;rectum: 24.3;small intestine: 11.0;stomach: 9.8 liver: 2.8 Cell line enhanced EFO-21: 1.8;HAP1: 1.4;RPTEC TERT1: 1.6 +WNT5A hWNT5A ENSG00000114251 Wnt family member 5A 3 55465715-55490539 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Colorectal cancer:2.94e-5 (favourable) Expressed in all Tissue enhanced endometrium: 45.3 urinary bladder: 35.4 Cell line enhanced BJ: 189.9;BJ hTERT+: 249.3;SiHa: 371.6;U-87 MG: 239.2 +PFKFB4 ENSG00000114268 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 3 48517684-48562015 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047719, HPA066058 Uncertain Approved Nucleoli Renal cancer:3.91e-8 (unfavourable), Cervical cancer:3.04e-4 (unfavourable) Expressed in all Tissue enhanced testis: 31.7 small intestine: 22.7 Cell line enhanced U-87 MG: 80.8;WM-115: 72.6 +COL7A1 EBD1, EBDCT, EBR1 ENSG00000114270 Collagen type VII alpha 1 chain 3 48564073-48595267 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016357, HPA042420 Enhanced Pancreatic cancer:3.86e-4 (unfavourable), Head and neck cancer:6.31e-4 (favourable) Expressed in all Tissue enriched 6 skin: 114.5 endometrium,prostate: 20.1 Cell line enhanced HBEC3-KT: 71.5;HDLM-2: 89.9;HeLa: 81.8;SiHa: 86.9 +FGF12 FGF12B, FHF1 ENSG00000114279 Fibroblast growth factor 12 3 192139395-192767764 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA071557 Approved Nucleoplasm
Cytosol Mixed Tissue enhanced adrenal gland: 46.7;cerebral cortex: 52.4;heart muscle: 89.9 spleen: 16.2 Cell line enhanced AF22: 14.9;NTERA-2: 10.3;SCLC-21H: 28.2;U-251 MG: 12.2;WM-115: 17.4 +PRKAR2A PRKAR2 ENSG00000114302 Protein kinase cAMP-dependent type II regulatory subunit alpha 3 48744597-48847846 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005023, HPA038268 Uncertain Supported Golgi apparatus
Vesicles
Microtubule organizing center Colorectal cancer:4.27e-5 (favourable), Liver cancer:1.97e-4 (unfavourable), Renal cancer:2.07e-4 (favourable) Expressed in all Expressed in all testis: 124.3 Mixed +HES1 bHLHb39, FLJ20408, HES-1, Hes1, HRY ENSG00000114315 Hes family bHLH transcription factor 1 3 194136145-194138732 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA066929 Supported Nucleus Urothelial cancer:2.04e-5 (favourable) Expressed in all Mixed thyroid gland: 97.8 Mixed +USP4 UNP, Unph ENSG00000114316 Ubiquitin specific peptidase 4 3 49277831-49340712 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018499 Approved Supported Plasma membrane
Cytosol Renal cancer:4.29e-5 (favourable), Lung cancer:4.46e-5 (favourable) Expressed in all Expressed in all testis: 56.8 Expressed in all +ACAP2 CENTB2, CNT-B2, KIAA0041 ENSG00000114331 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 3 195274736-195443078 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034807, HPA034808 Supported Approved Endosomes Expressed in all Expressed in all thyroid gland: 34.2 Expressed in all +ECT2 ARHGEF31 ENSG00000114346 Epithelial cell transforming 2 3 172750682-172821474 Predicted intracellular proteins Evidence at protein level HPA036363, HPA053261 Enhanced Nucleus
Cytosol Liver cancer:6.82e-6 (unfavourable), Renal cancer:1.19e-5 (unfavourable), Pancreatic cancer:2.24e-5 (unfavourable), Lung cancer:1.13e-4 (unfavourable) Expressed in all Mixed testis: 29.1 Expressed in all +GNAT1 CSNBAD3 ENSG00000114349 G protein subunit alpha transducin 1 3 50191612-50196516 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045393 Supported Not detected Tissue enhanced testis: 1.4 cerebral cortex: 0.3 Not detected +GNAI2 GIP, GNAI2B ENSG00000114353 G protein subunit alpha i2 3 50226292-50259355 Predicted intracellular proteins Evidence at protein level HPA007704 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Breast cancer:1.03e-4 (favourable) Expressed in all Expressed in all placenta: 330.6 Expressed in all +TFG FLJ36137, SPG57, TF6 ENSG00000114354 TRK-fused gene 3 100709331-100748966 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019473, HPA052206 Approved Approved Vesicles
Cytosol Pancreatic cancer:1.50e-4 (unfavourable), Liver cancer:5.48e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 164.5 Expressed in all +USP9Y DFFRY ENSG00000114374 Ubiquitin specific peptidase 9, Y-linked Y 12701231-12860839 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA057687 Uncertain Vesicles Tissue enhanced Tissue enhanced prostate: 9.9 seminal vesicle: 6.9 Cell line enhanced RPTEC TERT1: 13.3 +HYAL1 FUS2, HYAL-1, LUCA1, NAT6 ENSG00000114378 Hyaluronoglucosaminidase 1 3 50299889-50312381 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002112 Uncertain Renal cancer:1.56e-11 (favourable), Colorectal cancer:2.07e-4 (favourable) Expressed in all Tissue enhanced liver: 71.1;spleen: 69.3 kidney: 43.5 Cell line enhanced Hep G2: 66.6;SK-BR-3: 20.5 +TUSC2 C3orf11, FUS1, PAP, PDAP2 ENSG00000114383 Tumor suppressor candidate 2 3 50320027-50328251 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA030116 Approved Vesicles
Cytosol Renal cancer:8.70e-7 (favourable), Liver cancer:2.84e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 42.1 Expressed in all +NPRL2 NPR2, NPR2L, TUSC4 ENSG00000114388 NPR2-like, GATOR1 complex subunit 3 50347330-50351091 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038196, HPA038197 Approved Supported Cytosol Lung cancer:1.59e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 13.8 Expressed in all +RPL24 L24 ENSG00000114391 Ribosomal protein L24 3 101681091-101686782 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA051653 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:2.72e-5 (unfavourable), Thyroid cancer:8.25e-4 (favourable) Expressed in all Expressed in all ovary: 2893.2 Expressed in all +CYB561D2 101F6, TSP10 ENSG00000114395 Cytochrome b561 family member D2 3 50350695-50358460 Predicted membrane proteins Evidence at protein level HPA042817 Uncertain Renal cancer:6.16e-5 (favourable), Pancreatic cancer:1.86e-4 (favourable) Expressed in all Expressed in all epididymis: 28.5 Expressed in all +C3orf14 HT021 ENSG00000114405 Chromosome 3 open reading frame 14 3 62318973-62336213 Predicted intracellular proteins Evidence at transcript level HPA048286 Approved Approved Plasma membrane
Cytosol Renal cancer:4.33e-5 (favourable) Expressed in all Mixed breast: 62.2 Cell line enhanced MCF7: 415.8 +FXR1 ENSG00000114416 FMR1 autosomal homolog 1 3 180868141-180982753 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018246, HPA055475 Approved Enhanced Cytosol Renal cancer:2.19e-5 (unfavourable), Liver cancer:2.70e-4 (unfavourable), Endometrial cancer:5.96e-4 (unfavourable), Pancreatic cancer:7.30e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 276.6 Expressed in all +CBLB Cbl-b, RNF56 ENSG00000114423 Cbl proto-oncogene B 3 105655461-105869552 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA018327, HPA019880 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all lymph node: 28.0 Cell line enhanced U-138 MG: 63.4 +BBX HBP2, HSPC339, MDS001 ENSG00000114439 BBX, HMG-box containing 3 107522936-107811324 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006049, HPA050646 Enhanced Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 115.7 Expressed in all +IFT57 ESRRBL1, FLJ10147, HIPPI, MHS4R2 ENSG00000114446 Intraflagellar transport 57 3 108160812-108222570 Predicted intracellular proteins Evidence at protein level HPA035514, HPA035515 Supported Approved Nuclear speckles
Mitochondria
Cytosol Colorectal cancer:6.96e-5 (favourable), Ovarian cancer:7.63e-4 (favourable) Expressed in all Mixed testis: 67.1 Expressed in all +GNB4 ENSG00000114450 G protein subunit beta 4 3 179396089-179451590 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB018383, CAB018737, HPA040736 Enhanced Enhanced Plasma membrane Renal cancer:1.39e-6 (unfavourable) Expressed in all Mixed skin: 37.6 Mixed +HHLA2 B7-H5, B7H7, B7y ENSG00000114455 HERV-H LTR-associating 2 3 108296490-108378285 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055478 Enhanced Group enriched Group enriched 10 colon: 87.7;duodenum: 87.1;gallbladder: 46.0;rectum: 90.5;small intestine: 143.9 stomach: 9.2 Cell line enhanced HDLM-2: 3.7;Karpas-707: 2.0 +IQCG CFAP122, DKFZp434B227, DRC9 ENSG00000114473 IQ motif containing G 3 197889075-197960142 Predicted intracellular proteins Evidence at protein level HPA042787, HPA051981 Enhanced Approved Actin filaments
Cytosol Expressed in all Group enriched 6 fallopian tube: 83.6;testis: 78.8 thyroid gland: 13.9 Expressed in all +GBE1 ENSG00000114480 1,4-alpha-glucan branching enzyme 1 3 81489699-81762161 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038073, HPA038074, HPA038075 Enhanced Approved Nucleoplasm
Cytosol Expressed in all Expressed in all adipose tissue: 79.6 Expressed in all +MORC1 CT33, MORC, ZCW6 ENSG00000114487 MORC family CW-type zinc finger 1 3 108958239-109118142 Predicted intracellular proteins Evidence at protein level HPA036413 Supported Not detected Tissue enriched 68 testis: 29.7 epididymis: 0.4 Group enriched 7 Karpas-707: 1.8;RPMI-8226: 5.3 +UMPS ENSG00000114491 Uridine monophosphate synthetase 3 124730366-124749273 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036178, HPA036179 Uncertain Supported Cytosol Prostate cancer:9.20e-4 (unfavourable) Expressed in all Mixed parathyroid gland,spleen: 3.4 Expressed in all +NCBP2 Cbc2, CBP20, NIP1 ENSG00000114503 Nuclear cap binding protein subunit 2 3 196935402-196942597 Predicted intracellular proteins, Transporters Evidence at protein level HPA044850, HPA062483 Supported Enhanced Nucleoplasm Liver cancer:2.37e-7 (unfavourable), Prostate cancer:2.27e-4 (unfavourable), Pancreatic cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 79.3 Expressed in all +SNX4 ATG24B ENSG00000114520 Sorting nexin 4 3 125446644-125520197 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005709 Uncertain Renal cancer:5.01e-5 (favourable), Endometrial cancer:6.10e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 75.4 Expressed in all +C3orf52 FLJ23186, TTMP ENSG00000114529 Chromosome 3 open reading frame 52 3 112086335-112131004 Predicted membrane proteins Evidence at protein level HPA008119, HPA011968 Uncertain Pancreatic cancer:3.85e-4 (unfavourable) Mixed Tissue enhanced skin: 23.1 thyroid gland: 16.6 Cell line enhanced U-698: 37.5 +FRMD4B GRSP1, KIAA1013 ENSG00000114541 FERM domain containing 4B 3 69169990-69542583 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA009705 Uncertain Supported Renal cancer:5.01e-4 (favourable) Expressed in all Mixed thyroid gland: 44.4 Cell line enhanced HUVEC TERT2: 42.3 +SLC41A3 FLJ20473 ENSG00000114544 Solute carrier family 41 member 3 3 126006355-126101561 Predicted membrane proteins, Transporters Evidence at protein level HPA045847 Approved Supported Plasma membrane Liver cancer:1.49e-7 (unfavourable), Renal cancer:6.04e-7 (favourable) Expressed in all Expressed in all testis: 77.4 Expressed in all +ROPN1B ENSG00000114547 Rhophilin associated tail protein 1B 3 125969144-125983454 Predicted intracellular proteins Evidence at protein level HPA052530 Supported Tissue enhanced Tissue enriched 8 testis: 372.8 breast: 44.7 Group enriched 7 SK-MEL-30: 40.5;WM-115: 18.2 +PLXNA1 NOV, PLXN1 ENSG00000114554 Plexin A1 3 126988594-127037392 Predicted membrane proteins Evidence at protein level HPA007499, CAB012483 Uncertain Enhanced Nucleus
Cytosol Liver cancer:4.13e-6 (unfavourable), Renal cancer:5.64e-5 (unfavourable), Ovarian cancer:1.35e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 43.5 skin: 16.8 Mixed +ATP6V1A ATP6A1, ATP6V1A1, VA68, Vma1, VPP2 ENSG00000114573 ATPase H+ transporting V1 subunit A 3 113747019-113812056 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB006910, HPA035083, HPA035084 Approved Supported Nucleus
Vesicles
Cytosol Renal cancer:3.82e-12 (favourable) Expressed in all Expressed in all cerebral cortex: 151.4 Expressed in all +ABTB1 BPOZ, Btb3, BTBD21, EF1ABP ENSG00000114626 Ankyrin repeat and BTB domain containing 1 3 127672935-127680920 Predicted intracellular proteins Evidence at protein level HPA035022, HPA035023 Uncertain Supported Nucleoli
Cytosol Renal cancer:1.13e-4 (unfavourable) Expressed in all Expressed in all spleen: 50.2 Mixed +PODXL2 endoglycan, PODLX2 ENSG00000114631 Podocalyxin like 2 3 127629181-127672809 Predicted membrane proteins Evidence at protein level CAB024934, HPA042265 Approved Approved Golgi apparatus
Vesicles Expressed in all Tissue enhanced cerebral cortex: 77.1 testis: 35.9 Cell line enhanced SCLC-21H: 195.4 +UPK1B TSPAN20, UPK1 ENSG00000114638 Uroplakin 1B 3 119173517-119205153 Predicted membrane proteins, Transporters Evidence at protein level HPA031799, HPA031800 Enhanced Endometrial cancer:3.87e-5 (favourable), Stomach cancer:7.76e-4 (unfavourable) Tissue enhanced Tissue enhanced stomach: 33.1;urinary bladder: 36.1 tonsil: 15.4 Cell line enhanced CACO-2: 33.3;RPTEC TERT1: 27.6;RT4: 115.3 +CSPG5 NGC ENSG00000114646 Chondroitin sulfate proteoglycan 5 3 47562239-47580792 Predicted membrane proteins Evidence at protein level HPA049529, HPA067818, HPA071779 Enhanced Approved Nucleoplasm
Mitochondria Ovarian cancer:2.14e-4 (favourable) Tissue enriched Tissue enriched 56 cerebral cortex: 156.7 testis: 2.8 Cell line enhanced AF22: 32.2 +KLHL18 FLJ13703, KIAA0795 ENSG00000114648 Kelch like family member 18 3 47282917-47346816 Predicted intracellular proteins Evidence at protein level HPA035027, HPA035028 Approved Approved Nucleoplasm
Nuclear bodies Liver cancer:3.13e-4 (unfavourable) Expressed in all Expressed in all skin: 14.2 Expressed in all +SCAP KIAA0199 ENSG00000114650 SREBF chaperone 3 47413694-47477126 Predicted membrane proteins Evidence at protein level HPA004713 Approved Renal cancer:4.33e-5 (favourable), Pancreatic cancer:7.14e-4 (favourable) Expressed in all Expressed in all adrenal gland: 67.0 Expressed in all +EFCC1 C3orf73, CCDC48, FLJ12057 ENSG00000114654 EF-hand and coiled-coil domain containing 1 3 129001629-129040742 Predicted intracellular proteins Evidence at transcript level HPA042798, HPA050888 Uncertain Pancreatic cancer:9.70e-4 (favourable) Mixed Tissue enhanced lung: 4.9 spleen: 3.6 Cell line enhanced AF22: 1.3;HL-60: 3.0 +KIAA1257 ENSG00000114656 KIAA1257 3 128909866-129002690 Predicted intracellular proteins Evidence at transcript level HPA042811, HPA048445 Uncertain Approved Cell Junctions
Cytosol Mixed Tissue enriched 7 testis: 34.5 placenta: 5.1 Cell line enhanced AF22: 6.0;BEWO: 11.3;HL-60: 9.2;THP-1: 5.6 +NEK11 FLJ23495 ENSG00000114670 NIMA related kinase 11 3 131026850-131350465 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016908 Approved Supported Nucleoplasm Renal cancer:5.92e-6 (favourable), Cervical cancer:7.10e-4 (favourable) Mixed Tissue enhanced fallopian tube: 34.6 testis: 28.0 Mixed +MRPL3 MRL3, RPML3 ENSG00000114686 Mitochondrial ribosomal protein L3 3 131462212-131502983 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043665, HPA060132 Approved Liver cancer:4.33e-7 (unfavourable), Pancreatic cancer:3.51e-6 (unfavourable), Ovarian cancer:1.36e-4 (favourable) Expressed in all Expressed in all thyroid gland: 107.7 Expressed in all +PLSCR4 ENSG00000114698 Phospholipid scramblase 4 3 146192339-146251179 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA002276 Uncertain Approved Nucleoplasm
Nuclear bodies Endometrial cancer:3.90e-4 (unfavourable), Renal cancer:4.13e-4 (unfavourable) Expressed in all Expressed in all placenta: 80.2 Cell line enhanced ASC diff: 41.7;HUVEC TERT2: 42.5;TIME: 86.2 +HEMK1 MTQ1 ENSG00000114735 HemK methyltransferase family member 1 3 50569152-50596168 Predicted intracellular proteins Evidence at protein level HPA034701, HPA034702 Uncertain Expressed in all Expressed in all parathyroid gland: 32.3 Expressed in all +CISH CIS, CIS-1, G18, SOCS ENSG00000114737 Cytokine inducible SH2 containing protein 3 50606490-50611831 Predicted intracellular proteins Evidence at protein level CAB034039, HPA040812 Approved Approved Microtubules
Cytokinetic bridge Renal cancer:3.53e-12 (favourable), Endometrial cancer:1.13e-5 (favourable), Liver cancer:6.98e-4 (favourable), Pancreatic cancer:9.65e-4 (favourable) Expressed in all Mixed thyroid gland: 42.9 Group enriched 6 HDLM-2: 287.3;K-562: 65.9 +MAPKAPK3 3pK, MAPKAP3 ENSG00000114738 Mitogen-activated protein kinase-activated protein kinase 3 3 50611520-50649297 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058275 Supported Nucleoplasm Renal cancer:1.90e-8 (favourable), Colorectal cancer:8.08e-5 (favourable) Expressed in all Expressed in all heart muscle: 117.6 Expressed in all +ACVR2B ActR-IIB ENSG00000114739 Activin A receptor type 2B 3 38453851-38493142 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA007398, CAB025115, HPA040384 Approved Approved Nucleus
Nuclear bodies
Cytosol Expressed in all Mixed parathyroid gland: 6.4 Cell line enhanced AF22: 20.5;NTERA-2: 25.8 +WDR48 KIAA1449, P80, SPG60 ENSG00000114742 WD repeat domain 48 3 39051998-39096671 Predicted intracellular proteins Evidence at protein level HPA038421, HPA058015 Approved Supported Vesicles Renal cancer:1.63e-7 (favourable) Expressed in all Expressed in all testis: 72.5 Expressed in all +COMMD2 HSPC042 ENSG00000114744 COMM domain containing 2 3 149738470-149752499 Predicted intracellular proteins Evidence at protein level HPA044190 Uncertain Approved Nucleoplasm
Nuclear bodies Pancreatic cancer:3.69e-6 (unfavourable), Liver cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 23.5 Expressed in all +GORASP1 FLJ23443, GOLPH5, GRASP65, P65 ENSG00000114745 Golgi reassembly stacking protein 1 3 39096659-39108363 Predicted intracellular proteins Evidence at protein level HPA056283 Enhanced Supported Golgi apparatus Renal cancer:1.91e-6 (favourable), Endometrial cancer:6.92e-6 (favourable), Liver cancer:5.13e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 36.8 Expressed in all +PEX5L PEX5R, PXR2, TRIP8b ENSG00000114757 Peroxisomal biogenesis factor 5 like 3 179794958-180037053 Predicted intracellular proteins Evidence at protein level HPA058026 Enhanced Tissue enhanced Group enriched 9 cerebral cortex: 67.5;parathyroid gland: 94.8 testis: 8.6 Group enriched 5 HDLM-2: 7.2;MOLT-4: 22.2;RPMI-8226: 15.1;SCLC-21H: 15.0;U-266/70: 12.8 +RRP9 RNU3IP2, U3-55K ENSG00000114767 Ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 3 51933430-51941941 Predicted intracellular proteins Evidence at protein level HPA038798 Uncertain Supported Nucleus Liver cancer:2.90e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 18.9 Expressed in all +ABCC5 EST277145, MOAT-C, MRP5, SMRP ENSG00000114770 ATP binding cassette subfamily C member 5 3 183919934-184018015 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA044067, HPA052295 Uncertain Supported Nucleus
Plasma membrane
Cell Junctions Liver cancer:6.78e-8 (unfavourable), Prostate cancer:3.40e-4 (unfavourable) Expressed in all Expressed in all stomach: 72.6 Expressed in all +AADAC CES5A1, DAC ENSG00000114771 Arylacetamide deacetylase 3 151814037-151828488 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002911 Approved Ovarian cancer:5.58e-6 (favourable), Stomach cancer:2.19e-4 (unfavourable), Pancreatic cancer:5.02e-4 (unfavourable) Tissue enriched Group enriched 5 adrenal gland: 150.1;duodenum: 182.4;liver: 386.8;small intestine: 215.8 stomach: 43.5 Cell line enhanced A549: 7.3;EFO-21: 3.9;HBEC3-KT: 2.7 +ABHD14B CIB, MGC15429 ENSG00000114779 Abhydrolase domain containing 14B 3 51968510-51983409 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036444, HPA036642 Supported Supported Nucleus
Nucleoli
Cytosol Renal cancer:2.93e-5 (favourable), Endometrial cancer:5.42e-5 (favourable), Cervical cancer:6.92e-5 (favourable) Expressed in all Expressed in all thyroid gland: 90.8 Expressed in all +EIF1B GC20 ENSG00000114784 Eukaryotic translation initiation factor 1B 3 40309684-40312424 Predicted intracellular proteins Evidence at protein level Renal cancer:1.08e-5 (favourable), Liver cancer:1.94e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 231.3 Expressed in all +ABHD14A-ACY1 ENSG00000114786 ABHD14A-ACY1 readthrough 3 51974706-51989183 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036174, HPA036175, HPA038153 Approved Uncertain Vesicles Not detected Tissue enhanced small intestine: 1.7 kidney: 0.7 Cell line enhanced HUVEC TERT2: 1.3;SH-SY5Y: 1.3 +ARHGEF26 DKFZP434D146, SGEF ENSG00000114790 Rho guanine nucleotide exchange factor 26 3 154121003-154257827 Predicted intracellular proteins Evidence at protein level HPA017722, HPA049195 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:9.74e-4 (favourable) Expressed in all Mixed cerebral cortex,lung: 15.0 Cell line enhanced U-251 MG: 16.6 +KLHL24 DRE1, FLJ20059 ENSG00000114796 Kelch like family member 24 3 183635568-183684477 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056337 Uncertain Expressed in all Expressed in all parathyroid gland: 73.9 Expressed in all +PLCH1 DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3 ENSG00000114805 Phospholipase C eta 1 3 155375580-155745067 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036176, HPA057978 Uncertain Enhanced Vesicles Renal cancer:3.03e-5 (favourable) Mixed Tissue enhanced testis: 20.6 fallopian tube: 13.0 Cell line enhanced AF22: 38.5;NTERA-2: 20.8 +VIPR1 HVR1, RDC1, VPAC1, VPAC1R ENSG00000114812 Vasoactive intestinal peptide receptor 1 3 42489299-42537573 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA026777 Approved Tissue enhanced Tissue enhanced lung: 60.0 duodenum: 34.4 Cell line enhanced CAPAN-2: 53.2;RT4: 34.8;WM-115: 77.3 +DNAH1 DNAHC1, HDHC7, HL-11, HL11, XLHSRF-1 ENSG00000114841 Dynein axonemal heavy chain 1 3 52316319-52400491 Predicted intracellular proteins Evidence at protein level HPA036805, HPA036806 Uncertain Mixed Mixed testis: 7.8 Mixed +SSR3 TRAPG ENSG00000114850 Signal sequence receptor subunit 3 3 156540140-156555184 Predicted membrane proteins Evidence at protein level HPA014906 Approved Approved Uncertain Cytosol Liver cancer:4.46e-7 (unfavourable), Renal cancer:2.84e-4 (unfavourable), Head and neck cancer:3.43e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 204.7 Expressed in all +ZBTB47 DKFZp434N0615, KIAA1190, ZNF651 ENSG00000114853 Zinc finger and BTB domain containing 47 3 42653684-42665854 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA074057 Approved Nucleoplasm Renal cancer:7.96e-5 (favourable) Expressed in all Expressed in all heart muscle: 50.0 Cell line enhanced ASC diff: 42.2 +TNNC1 TNNC ENSG00000114854 Troponin C1, slow skeletal and cardiac type 3 52451102-52454070 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002450, HPA044848, HPA056897 Enhanced Approved Nucleoplasm
Actin filaments
Mitochondria Mixed Group enriched 16 heart muscle: 4938.6;skeletal muscle: 7104.7 esophagus: 383.0 Cell line enhanced CACO-2: 53.1;EFO-21: 58.5;HSkMC: 46.0;U-2 OS: 99.1 +NKTR p104 ENSG00000114857 Natural killer cell triggering receptor 3 42600614-42648741 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022120, HPA051576 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:1.05e-5 (favourable), Head and neck cancer:1.26e-4 (favourable), Renal cancer:5.02e-4 (unfavourable), Prostate cancer:6.01e-4 (unfavourable) Expressed in all Expressed in all testis: 24.3 Expressed in all +CLCN2 ClC-2, CLC2, EJM6 ENSG00000114859 Chloride voltage-gated channel 2 3 184346185-184361651 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB009397, HPA014545, HPA024108 Approved Approved Cytosol Liver cancer:4.67e-8 (unfavourable) Expressed in all Mixed testis: 17.7 Mixed +FOXP1 12CC4, hFKH1B, HSPC215, QRF1 ENSG00000114861 Forkhead box P1 3 70954693-71583989 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003876, CAB011501 Supported Enhanced Nucleoplasm Expressed in all Expressed in all ovary: 39.7 Expressed in all +EIF4G1 EIF4F, EIF4G, p220, PARK18 ENSG00000114867 Eukaryotic translation initiation factor 4 gamma 1 3 184314495-184335358 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB014774, HPA028487, HPA043866 Approved Enhanced Cytosol Liver cancer:7.99e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 210.0 Expressed in all +SPCS1 HSPC033, SPC1, SPC12, YJR010C-A ENSG00000114902 Signal peptidase complex subunit 1 3 52704955-52711146 Predicted membrane proteins Evidence at protein level HPA046091, HPA055273 Supported Approved Golgi apparatus
Vesicles Renal cancer:2.90e-4 (favourable), Colorectal cancer:9.28e-4 (favourable) Expressed in all Expressed in all testis: 216.1 Expressed in all +NEK4 NRK2, pp12301, STK2 ENSG00000114904 NIMA related kinase 4 3 52708449-52770949 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015750, HPA058543 Approved Supported Cytosol Colorectal cancer:2.69e-5 (favourable) Expressed in all Expressed in all testis: 84.3 Expressed in all +SLC4A3 AE3, SLC2C ENSG00000114923 Solute carrier family 4 member 3 2 219627327-219641980 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA063498 Approved Nucleoplasm Urothelial cancer:4.12e-4 (unfavourable) Expressed in all Group enriched 6 cerebral cortex: 30.0;heart muscle: 119.1;ovary: 47.7 testis: 10.9 Mixed +INO80D FLJ20309 ENSG00000114933 INO80 complex subunit D 2 205993721-206086303 Predicted intracellular proteins Evidence at protein level HPA043976 Approved Head and neck cancer:5.53e-4 (favourable) Expressed in all Mixed bone marrow: 11.3 Mixed +EEF1B2 ENSG00000114942 Eukaryotic translation elongation factor 1 beta 2 2 206159585-206162928 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012477, HPA035029 Supported Approved Nucleoli fibrillar center
Cytosol Renal cancer:3.62e-6 (unfavourable), Breast cancer:2.60e-4 (favourable), Melanoma:9.95e-4 (unfavourable) Expressed in all Expressed in all breast: 515.5 Expressed in all +ADAM23 MDC3 ENSG00000114948 ADAM metallopeptidase domain 23 2 206443539-206621130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012130, CAB033276 Uncertain Mixed Group enriched 6 cerebral cortex: 55.4;parathyroid gland: 135.3 heart muscle: 16.5 Cell line enhanced RH-30: 61.7;RPMI-8226: 120.2 +DGUOK dGK ENSG00000114956 Deoxyguanosine kinase 2 73926826-73958961 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA034766, HPA057246 Approved Renal cancer:8.69e-7 (unfavourable), Urothelial cancer:7.47e-4 (favourable) Expressed in all Expressed in all testis: 56.6 Expressed in all +MOB1A C2orf6, FLJ10788, FLJ11595, Mats1, MOB1, Mob4B, MOBK1B, MOBKL1B ENSG00000114978 MOB kinase activator 1A 2 74152528-74178898 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047088, HPA071690 Supported Approved Nucleus
Nucleoli
Cytosol Liver cancer:3.34e-4 (unfavourable) Expressed in all Expressed in all lymph node: 107.8 Expressed in all +KANSL3 FLJ10081, KIAA1310, NSL3, Rcd1 ENSG00000114982 KAT8 regulatory NSL complex subunit 3 2 96593170-96642787 Predicted intracellular proteins Evidence at protein level HPA035017, HPA035018, HPA041280 Approved Enhanced Nucleus Liver cancer:5.34e-4 (unfavourable) Expressed in all Expressed in all testis: 28.3 Expressed in all +LMAN2L DKFZp564L2423, VIPL ENSG00000114988 Lectin, mannose binding 2 like 2 96705929-96740064 Disease related genes, Predicted membrane proteins Evidence at protein level HPA026600 Approved Expressed in all Mixed fallopian tube: 28.0 Expressed in all +RTKN B5 ENSG00000114993 Rhotekin 2 74425836-74442422 Predicted intracellular proteins Evidence at protein level HPA030259 Approved Approved Nucleoplasm
Mitochondria Expressed in all Mixed cerebral cortex: 56.0 Mixed +TTL MGC46235 ENSG00000114999 Tubulin tyrosine ligase 2 112482154-112541739 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA066819 Approved Nucleoplasm
Vesicles Liver cancer:5.65e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 4.4 Mixed +IL1A IL-1A, IL1, IL1-ALPHA, IL1F1 ENSG00000115008 Interleukin 1 alpha 2 112773915-112784590 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level Lung cancer:1.54e-4 (unfavourable), Stomach cancer:4.03e-4 (unfavourable), Cervical cancer:9.52e-4 (unfavourable) Tissue enhanced Tissue enhanced esophagus: 12.8;testis: 18.6 tonsil: 7.4 Cell line enhanced HBEC3-KT: 302.4;hTCEpi: 147.6;hTERT-HME1: 205.8 +CCL20 CKb4, exodus-1, LARC, MIP-3a, SCYA20, ST38 ENSG00000115009 C-C motif chemokine ligand 20 2 227813842-227817564 Predicted secreted proteins Evidence at protein level Renal cancer:9.19e-8 (unfavourable), Pancreatic cancer:2.73e-4 (unfavourable), Liver cancer:9.29e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 269.7;tonsil: 155.2 urinary bladder: 83.4 Cell line enhanced Hep G2: 23.9;NB-4: 12.7;RT4: 12.0 +PIKFYVE FAB1, KIAA0981, MGC40423, p235, PIKfyve, PIP5K, PIP5K3, ZFYVE29 ENSG00000115020 Phosphoinositide kinase, FYVE-type zinc finger containing 2 208266267-208358751 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042604 Uncertain Uncertain Nuclear speckles Head and neck cancer:6.81e-4 (favourable) Expressed in all Expressed in all testis: 25.8 Expressed in all +KCNIP3 CSEN, DREAM, KCHIP3 ENSG00000115041 Potassium voltage-gated channel interacting protein 3 2 95297304-95386083 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA069797 Approved Endometrial cancer:1.58e-5 (unfavourable) Mixed Tissue enhanced cerebral cortex: 40.6;parathyroid gland: 44.0 thyroid gland: 28.0 Cell line enhanced BJ hTERT+: 14.6;RPTEC TERT1: 26.5;U-138 MG: 16.1 +FAHD2A CGI-105 ENSG00000115042 Fumarylacetoacetate hydrolase domain containing 2A 2 95402721-95416616 Predicted intracellular proteins Evidence at protein level HPA042145, HPA044987, CAB045971, CAB045972 Enhanced Expressed in all Expressed in all liver: 52.8 Expressed in all +NCL C23 ENSG00000115053 Nucleolin 2 231453531-231483641 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004210, HPA023981 Supported Enhanced Nucleus
Nucleoli Liver cancer:1.41e-6 (unfavourable), Endometrial cancer:2.28e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 449.8 Expressed in all +ACTR1B Arp1B, CTRN2 ENSG00000115073 ARP1 actin-related protein 1 homolog B, centractin beta 2 97655963-97664107 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047443 Approved Microtubules Urothelial cancer:4.69e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 82.0 Expressed in all +SLC35F5 FLJ22004 ENSG00000115084 Solute carrier family 35 member F5 2 113705011-113756823 Predicted membrane proteins, Transporters Evidence at protein level HPA034828, HPA049229 Uncertain Uncertain Plasma membrane Renal cancer:1.71e-5 (favourable), Cervical cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 97.7 Expressed in all +ZAP70 SRK, STD, ZAP-70 ENSG00000115085 Zeta chain of T-cell receptor associated protein kinase 70 2 97713560-97739862 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002625, HPA003134 Enhanced Renal cancer:3.02e-8 (unfavourable), Endometrial cancer:9.66e-8 (favourable), Head and neck cancer:3.93e-6 (favourable), Cervical cancer:6.89e-5 (favourable) Mixed Tissue enhanced appendix: 36.2;lymph node: 64.3;spleen: 37.7 tonsil: 16.2 Cell line enriched 16 MOLT-4: 144.9 +ACTR3 ARP3 ENSG00000115091 ARP3 actin related protein 3 homolog 2 113889960-113962596 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005085, HPA047016, HPA051683 Approved Renal cancer:3.81e-5 (unfavourable), Cervical cancer:6.52e-5 (unfavourable), Liver cancer:7.76e-5 (unfavourable) Expressed in all Expressed in all lymph node: 335.6 Expressed in all +STEAP3 dudlin-2, STMP3, TSAP6 ENSG00000115107 STEAP3 metalloreductase 2 119223831-119265652 Disease related genes, Predicted membrane proteins Evidence at protein level HPA050510 Uncertain Approved Nucleoli
Cytosol Renal cancer:0.00e+0 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 194.5 liver: 53.0 Cell line enhanced U-87 MG: 145.7 +EPB41L5 BE37, FLJ12957, KIAA1548, YMO1, YRT ENSG00000115109 Erythrocyte membrane protein band 4.1 like 5 2 120013005-120179119 Predicted intracellular proteins Evidence at protein level HPA037563, HPA037564 Uncertain Supported Plasma membrane Renal cancer:2.28e-6 (favourable) Expressed in all Mixed testis: 56.5 Cell line enhanced MCF7: 63.7 +TFCP2L1 CRTR1, LBP-9 ENSG00000115112 Transcription factor CP2 like 1 2 121216587-121285207 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029708 Uncertain Supported Nucleoli fibrillar center Renal cancer:7.72e-6 (favourable) Mixed Tissue enhanced kidney: 49.0 thyroid gland: 45.7 Cell line enhanced BEWO: 17.6;HEL: 14.0;hTCEpi: 12.5;RPTEC TERT1: 32.4;RT4: 25.3;SCLC-21H: 15.6 +SF3B6 CGI-110, Ht006, P14, SAP14a, SF3B14a ENSG00000115128 Splicing factor 3b subunit 6 2 24067584-24076443 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034829, HPA034830 Enhanced Supported Nucleoplasm Liver cancer:5.57e-5 (unfavourable), Renal cancer:1.74e-4 (unfavourable), Pancreatic cancer:8.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 153.3 Expressed in all +TP53I3 PIG3 ENSG00000115129 Tumor protein p53 inducible protein 3 2 24077433-24085861 Predicted intracellular proteins Evidence at protein level CAB017479, HPA022012, HPA028742 Enhanced Supported Vesicles Expressed in all Expressed in all esophagus: 97.1 Cell line enriched 7 T-47d: 553.5 +DNAJC27 RabJS, RBJ ENSG00000115137 DnaJ heat shock protein family (Hsp40) member C27 2 24943636-24972094 Predicted intracellular proteins Evidence at protein level HPA036815, HPA036816 Uncertain Supported Cytosol Renal cancer:8.48e-5 (favourable) Mixed Tissue enhanced testis: 39.5 cerebral cortex: 8.7 Mixed +POMC ACTH, CLIP, LPH, MSH, NPP, POC ENSG00000115138 Proopiomelanocortin 2 25160853-25168903 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level CAB002762, HPA046135, HPA063644 Enhanced Pancreatic cancer:5.70e-4 (favourable) Tissue enriched Tissue enhanced testis: 6.8 pancreas: 5.3 Cell line enhanced HMC-1: 1.2;THP-1: 1.2 +STAM2 Hbp ENSG00000115145 Signal transducing adaptor molecule 2 2 152116801-152175992 Predicted intracellular proteins Evidence at protein level HPA035528, HPA035529 Enhanced Supported Nucleoplasm
Vesicles
Cytosol Expressed in all Expressed in all thyroid gland: 22.8 Expressed in all +OTOF DFNB6, DFNB9, FER1L2 ENSG00000115155 Otoferlin 2 26457203-26558698 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012410 Approved Not detected Tissue enhanced bone marrow: 4.3 cerebral cortex: 1.1 Cell line enriched 20 HDLM-2: 30.8 +GPD2 ENSG00000115159 Glycerol-3-phosphate dehydrogenase 2 2 156435290-156613735 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008012, HPA045506 Enhanced Liver cancer:1.44e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 45.7 Mixed +CENPA CenH3, CENP-A ENSG00000115163 Centromere protein A 2 26764289-26801067 Predicted intracellular proteins Evidence at protein level CAB008371, HPA073086 Enhanced Supported Nucleoplasm Liver cancer:2.88e-8 (unfavourable), Pancreatic cancer:1.30e-4 (unfavourable), Endometrial cancer:2.38e-4 (unfavourable), Lung cancer:3.70e-4 (unfavourable) Mixed Tissue enhanced lymph node: 7.4 tonsil: 6.5 Mixed +CYTIP B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP ENSG00000115165 Cytohesin 1 interacting protein 2 157414619-157488961 Predicted intracellular proteins Evidence at protein level HPA007191 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:9.12e-4 (favourable) Expressed in all Tissue enhanced lymph node: 101.8;tonsil: 102.0 appendix: 92.4 Cell line enhanced HDLM-2: 41.0;Karpas-707: 103.6;U-266/70: 185.5;U-266/84: 68.5 +ACVR1 ACVR1A, ACVRLK2, ALK2, SKR1 ENSG00000115170 Activin A receptor type 1 2 157736444-157875862 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007505, HPA046514 Approved Approved Nucleoli
Cytosol Urothelial cancer:5.17e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 74.2 Mixed +TANC1 KIAA1728, ROLSB ENSG00000115183 Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 2 158968671-159232659 Predicted intracellular proteins Evidence at protein level HPA036750 Approved Expressed in all Mixed skin: 24.7 Mixed +SLC30A3 ZNT3 ENSG00000115194 Solute carrier family 30 member 3 2 27253684-27275817 Predicted membrane proteins, Transporters Evidence at protein level HPA060505, HPA067637, CAB079044 Enhanced Approved Approved Nucleus
Nucleoli
Vesicles
Cytosol Mixed Group enriched 12 cerebral cortex: 36.6;epididymis: 55.4;testis: 43.5 heart muscle: 3.6 Cell line enhanced HAP1: 10.6;Hep G2: 9.5;REH: 20.7;RH-30: 11.0 +MPV17 SYM1 ENSG00000115204 MPV17, mitochondrial inner membrane protein 2 27309492-27325680 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Liver cancer:6.99e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 84.3 Expressed in all +GTF3C2 KIAA0011, TFIIIC110 ENSG00000115207 General transcription factor IIIC subunit 2 2 27325849-27357034 Predicted intracellular proteins Evidence at protein level HPA035836 Uncertain Liver cancer:1.21e-8 (unfavourable), Endometrial cancer:8.25e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 56.0 Expressed in all +EIF2B4 DKFZP586J0119, EIF-2B, EIF2B, EIF2Bdelta ENSG00000115211 Eukaryotic translation initiation factor 2B subunit delta 2 27364352-27370486 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB032234, HPA039993 Uncertain Approved Nuclear membrane
Actin filaments Renal cancer:5.46e-8 (unfavourable), Liver cancer:1.83e-4 (unfavourable) Expressed in all Expressed in all testis: 52.0 Expressed in all +NRBP1 BCON3, MADM, MUDPNP, NRBP ENSG00000115216 Nuclear receptor binding protein 1 2 27427790-27442259 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029527, CAB033078 Supported Supported Cytosol Liver cancer:2.22e-5 (unfavourable), Renal cancer:5.84e-5 (unfavourable) Expressed in all Expressed in all testis: 125.8 Expressed in all +ITGB6 ENSG00000115221 Integrin subunit beta 6 2 160099666-160271888 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA023626, CAB073536 Approved Approved Nucleoplasm
Cell Junctions
Centrosome Pancreatic cancer:5.03e-6 (unfavourable) Mixed Tissue enhanced lung: 66.9 urinary bladder: 30.3 Cell line enhanced CAPAN-2: 122.2;RPTEC TERT1: 206.4 +FNDC4 FLJ22362, FRCP1 ENSG00000115226 Fibronectin type III domain containing 4 2 27491883-27495245 Predicted membrane proteins Evidence at transcript level HPA051804, HPA063581 Uncertain Approved Nucleoplasm
Aggresome
Cytosol Endometrial cancer:5.07e-4 (unfavourable), Urothelial cancer:6.11e-4 (unfavourable) Expressed in all Tissue enhanced adrenal gland: 72.5 cerebral cortex: 35.9 Cell line enhanced AN3-CA: 31.3;HUVEC TERT2: 34.8;SH-SY5Y: 33.9;TIME: 31.2 +ITGA4 CD49D ENSG00000115232 Integrin subunit alpha 4 2 181457202-181536187 Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA074961 Approved Plasma membrane Renal cancer:3.08e-5 (unfavourable), Head and neck cancer:8.29e-4 (favourable) Mixed Tissue enhanced spleen: 67.6 appendix: 49.6 Cell line enhanced fHDF/TERT166: 148.2;HEL: 275.3;MOLT-4: 291.8 +PSMD14 pad1, POH1, Rpn11 ENSG00000115233 Proteasome 26S subunit, non-ATPase 14 2 161308038-161411717 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002114, HPA003828 Approved Supported Nucleoplasm Liver cancer:2.66e-8 (unfavourable), Renal cancer:3.10e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 56.1 Expressed in all +SNX17 KIAA0064 ENSG00000115234 Sorting nexin 17 2 27370496-27377533 Predicted intracellular proteins Evidence at protein level HPA043867 Supported Supported Vesicles Expressed in all Expressed in all fallopian tube: 97.8 Expressed in all +ASB3 ASB-3 ENSG00000115239 Ankyrin repeat and SOCS box containing 3 2 53532672-53787610 Predicted intracellular proteins Evidence at protein level HPA003940 Uncertain Mixed Expressed in all cerebral cortex: 28.0 Expressed in all +PPM1G PP2CG, PP2Cgamma ENSG00000115241 Protein phosphatase, Mg2+/Mn2+ dependent 1G 2 27381194-27409687 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035530, HPA035531 Enhanced Enhanced Nucleoplasm Liver cancer:3.14e-7 (unfavourable), Ovarian cancer:6.08e-5 (favourable) Expressed in all Tissue enriched 5 testis: 337.3 lymph node: 65.2 Expressed in all +PDE1A ENSG00000115252 Phosphodiesterase 1A 2 182140036-182523192 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022151 Approved Approved Nucleoplasm Tissue enhanced Tissue enhanced thyroid gland: 76.5 testis: 63.0 Cell line enhanced ASC diff: 25.5;HHSteC: 18.5;HSkMC: 34.2 +REEP6 C19orf32, DP1L1, FLJ25383, Yip2f ENSG00000115255 Receptor accessory protein 6 19 1490747-1497927 Disease related genes, Predicted membrane proteins Evidence at protein level HPA003895, HPA048015 Enhanced Supported Endoplasmic reticulum Expressed in all Group enriched 7 adrenal gland: 48.2;duodenum: 166.1;liver: 76.1;small intestine: 167.0;testis: 181.2 prostate: 19.3 Cell line enhanced K-562: 101.6;T-47d: 84.9 +PCSK4 DKFZp434B217, MGC34749, PC4, SPC5 ENSG00000115257 Proprotein convertase subtilisin/kexin type 4 19 1481428-1490752 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005572 Uncertain Endometrial cancer:9.45e-5 (favourable) Expressed in all Tissue enriched 9 testis: 41.3 fallopian tube: 4.8 Cell line enhanced AN3-CA: 6.5;HMC-1: 3.2;U-266/70: 5.8 +GCG GLP1, GLP2, GRPP ENSG00000115263 Glucagon 2 162142873-162152404 Predicted secreted proteins Evidence at protein level CAB000040, HPA036760, HPA036761 Enhanced Supported Endoplasmic reticulum
Vesicles Tissue enriched Tissue enhanced pancreas: 346.3;rectum: 137.2;small intestine: 123.9 colon: 69.4 Group enriched 7 EFO-21: 100.6;U-2 OS: 158.1 +APC2 APCL ENSG00000115266 APC2, WNT signaling pathway regulator 19 1446302-1473244 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA078002 Supported Cytokinetic bridge
Midbody
Cytosol Tissue enriched Tissue enriched 21 cerebral cortex: 70.5 adrenal gland: 3.3 Group enriched 10 AF22: 7.7;SCLC-21H: 11.0;SH-SY5Y: 33.6 +IFIH1 Hlcd, IDDM19, MDA-5, MDA5 ENSG00000115267 Interferon induced with helicase C domain 1 2 162267079-162318703 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002656 Approved Expressed in all Mixed spleen: 31.1 Cell line enhanced BJ hTERT+ SV40 Large T+: 72.5;BJ hTERT+ SV40 Large T+ RasG12V: 93.7 +RPS15 MGC111130, RIG, S15 ENSG00000115268 Ribosomal protein S15 19 1438358-1440494 Cancer-related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA054510, HPA057793 Enhanced Approved Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 1335.2 Expressed in all +GCA GCL ENSG00000115271 Grancalcin 2 162318840-162371595 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035033, HPA035034 Enhanced Supported Plasma membrane
Cytosol Expressed in all Tissue enhanced bone marrow: 214.5 appendix: 88.0 Mixed +INO80B hIes2, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4 ENSG00000115274 INO80 complex subunit B 2 74455023-74457960 Predicted intracellular proteins Evidence at protein level HPA070644 Supported Nucleus
Nucleoli Renal cancer:1.56e-5 (unfavourable), Breast cancer:2.89e-4 (favourable), Stomach cancer:8.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 42.2 Expressed in all +MOGS CWH41, DER7, GCS1 ENSG00000115275 Mannosyl-oligosaccharide glucosidase 2 74461057-74465410 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011322, HPA011969 Approved Enhanced Endoplasmic reticulum Renal cancer:2.79e-8 (unfavourable), Liver cancer:2.34e-6 (unfavourable), Colorectal cancer:5.33e-4 (unfavourable) Expressed in all Expressed in all duodenum: 63.1 Expressed in all +TTC31 FLJ12788 ENSG00000115282 Tetratricopeptide repeat domain 31 2 74483073-74494886 Predicted intracellular proteins Evidence at protein level HPA041783 Uncertain Approved Nucleoplasm
Cytosol Urothelial cancer:2.49e-4 (favourable), Endometrial cancer:6.70e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 11.8 Expressed in all +NDUFS7 CI-20, FLJ45860, FLJ46880, PSST ENSG00000115286 NADH:ubiquinone oxidoreductase core subunit S7 19 1383527-1395589 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Renal cancer:4.90e-7 (favourable), Cervical cancer:2.03e-4 (favourable) Expressed in all Tissue enhanced skeletal muscle: 96.7 duodenum: 40.7 Mixed +PCGF1 MGC10882, NSPC1, RNF68 ENSG00000115289 Polycomb group ring finger 1 2 74505043-74508580 Predicted intracellular proteins Evidence at protein level HPA011356, HPA069156 Enhanced Enhanced Nucleoplasm Renal cancer:1.69e-4 (unfavourable) Expressed in all Mixed thyroid gland: 5.2 Expressed in all +GRB14 ENSG00000115290 Growth factor receptor bound protein 14 2 164492812-164621848 Predicted intracellular proteins Evidence at protein level CAB022294, HPA035052, HPA035053 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced epididymis: 6.1;kidney: 6.2;liver: 6.6 testis: 4.3 Cell line enhanced HUVEC TERT2: 7.9;RPTEC TERT1: 5.9;TIME: 9.9 +CLIP4 FLJ21069, RSNL2 ENSG00000115295 CAP-Gly domain containing linker protein family member 4 2 29097705-29189643 Predicted intracellular proteins Evidence at protein level HPA043366, HPA056246 Uncertain Enhanced Vesicles Renal cancer:1.83e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 55.8 Mixed +TLX2 Enx, HOX11L1, NCX, Tlx2 ENSG00000115297 T-cell leukemia homeobox 2 2 74513463-74517147 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA040969, HPA062254 Uncertain Approved Nucleoplasm Mixed Tissue enhanced adrenal gland: 2.7 testis: 0.8 Cell line enriched 17 SH-SY5Y: 68.4 +SPTBN1 ENSG00000115306 Spectrin beta, non-erythrocytic 1 2 54456285-54671445 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012685, HPA013149 Supported Approved Golgi apparatus Renal cancer:2.59e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 376.6 Mixed +AUP1 ENSG00000115307 Ancient ubiquitous protein 1 2 74526645-74529939 Predicted membrane proteins Evidence at protein level HPA007674 Approved Approved Nucleoplasm
Vesicles Renal cancer:2.97e-9 (unfavourable), Liver cancer:2.29e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 58.2 Expressed in all +RTN4 ASY, KIAA0886, NOGO, NSP-CL ENSG00000115310 Reticulon 4 2 54972187-55112621 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB005388, HPA023977 Supported Enhanced Endoplasmic reticulum Head and neck cancer:1.00e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 636.8 Expressed in all +HTRA2 OMI, PARK13, PRSS25 ENSG00000115317 HtrA serine peptidase 2 2 74529377-74533348 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB004004, HPA006602, HPA027366 Uncertain Supported Mitochondria Liver cancer:7.77e-8 (unfavourable) Expressed in all Mixed spleen: 9.0 Expressed in all +LOXL3 ENSG00000115318 Lysyl oxidase like 3 2 74532414-74555690 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035281 Approved Renal cancer:7.97e-8 (unfavourable) Tissue enhanced Mixed placenta: 21.6 Cell line enhanced U-138 MG: 238.3;WM-115: 524.2 +DOK1 p62dok ENSG00000115325 Docking protein 1 2 74549026-74557554 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004224, HPA048561 Approved Supported Cytosol Renal cancer:3.16e-6 (unfavourable), Lung cancer:4.64e-4 (favourable), Endometrial cancer:8.42e-4 (favourable) Expressed in all Mixed appendix,spleen: 8.7 Cell line enhanced HDLM-2: 54.7 +GALNT3 GalNAc-T3, HFTC, HHS ENSG00000115339 Polypeptide N-acetylgalactosaminyltransferase 3 2 165747591-165794682 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007613 Enhanced Supported Golgi apparatus Cervical cancer:2.08e-4 (unfavourable), Head and neck cancer:4.10e-4 (unfavourable) Expressed in all Mixed stomach: 86.1 Cell line enhanced CAPAN-2: 92.9;HaCaT: 108.1;hTCEpi: 82.6 +POLE4 p12 ENSG00000115350 DNA polymerase epsilon 4, accessory subunit 2 74958492-74970128 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA054979, HPA071815 Approved Approved Nucleus
Cytosol Liver cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 12.8 Mixed +TACR1 NK1R, NKIR, SPR, TAC1R ENSG00000115353 Tachykinin receptor 1 2 75046463-75199700 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA074573 Enhanced Mixed Tissue enhanced cervix, uterine: 7.3 fallopian tube: 4.7 Not detected +CCDC88A APE, FLJ10392, GIV, GRDN, HkRP1, KIAA1212 ENSG00000115355 Coiled-coil domain containing 88A 2 55287842-55419921 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038101, HPA038102 Enhanced Renal cancer:5.98e-8 (unfavourable), Endometrial cancer:2.06e-4 (unfavourable), Liver cancer:4.86e-4 (unfavourable) Expressed in all Expressed in all testis: 117.5 Mixed +ACADL ACAD4, LCAD ENSG00000115361 Acyl-CoA dehydrogenase, long chain 2 210187939-210225491 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA011990 Enhanced Supported Renal cancer:1.58e-11 (favourable) Group enriched Tissue enhanced thyroid gland: 32.0 prostate: 27.0 Cell line enhanced HAP1: 1.6;HeLa: 2.5;RPTEC TERT1: 2.5;U-2 OS: 1.9 +EVA1A FAM176A, FLJ13391, TMEM166 ENSG00000115363 Eva-1 homolog A, regulator of programmed cell death 2 75469302-75569722 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008055 Approved Supported Vesicles
Plasma membrane Ovarian cancer:5.67e-4 (favourable), Renal cancer:5.80e-4 (favourable) Mixed Tissue enhanced liver: 98.9 lung: 31.1 Cell line enhanced U-138 MG: 109.1 +MRPL19 KIAA0104, MRP-L15, RLX1, RPML15 ENSG00000115364 Mitochondrial ribosomal protein L19 2 75646783-75690851 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046805, HPA056622 Approved Supported Mitochondria Pancreatic cancer:1.97e-5 (unfavourable), Colorectal cancer:7.39e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 66.4 Expressed in all +LANCL1 GPR69A, p40 ENSG00000115365 LanC like 1 2 210431249-210477652 Predicted intracellular proteins Evidence at protein level HPA034994 Approved Approved Microtubules Expressed in all Expressed in all cerebral cortex: 153.3 Expressed in all +WDR75 FLJ12519, NET16, UTP17 ENSG00000115368 WD repeat domain 75 2 189441433-189475565 Predicted intracellular proteins Evidence at protein level HPA038199 Approved Approved Nucleoplasm Renal cancer:3.15e-11 (unfavourable), Liver cancer:6.50e-8 (unfavourable) Expressed in all Expressed in all endometrium: 39.6 Expressed in all +EFEMP1 DHRD, FBLN3, FBNL, MTLV, S1-5 ENSG00000115380 EGF containing fibulin like extracellular matrix protein 1 2 55865967-55924139 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016368, HPA049806, HPA070841, HPA071588 Supported Uncertain Mitochondria Renal cancer:3.89e-8 (unfavourable), Urothelial cancer:6.68e-5 (unfavourable), Endometrial cancer:4.72e-4 (unfavourable) Expressed in all Mixed placenta: 488.7 Group enriched 5 HHSteC: 719.8;HSkMC: 733.9;HUVEC TERT2: 3552.1;TIME: 3104.2 +REG1A PSP, PSPS, PSPS1, PTP, REG ENSG00000115386 Regenerating family member 1 alpha 2 79120362-79123419 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB025138, HPA045549, HPA045579 Enhanced Group enriched Group enriched 9 duodenum: 7122.5;pancreas: 10867.0;small intestine: 4615.5 stomach: 847.5 Cell line enhanced BEWO: 11.1;EFO-21: 16.2;HDLM-2: 13.2;RPMI-8226: 20.2;SH-SY5Y: 12.6;U-2 OS: 28.7 +FANCL FAAP43, FLJ10335, PHF9, Pog ENSG00000115392 Fanconi anemia complementation group L 2 58159243-58241372 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033842, HPA036685, HPA036686 Supported Approved Nuclear bodies
Vesicles Renal cancer:1.12e-7 (unfavourable), Liver cancer:2.81e-7 (unfavourable), Urothelial cancer:7.80e-5 (favourable) Expressed in all Expressed in all adrenal gland: 44.6 Expressed in all +FN1 CIG, FINC, GFND2, LETS, MSF ENSG00000115414 Fibronectin 1 2 215360440-215436172 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000126, HPA027066 Enhanced Renal cancer:3.44e-8 (unfavourable), Stomach cancer:8.82e-5 (unfavourable), Urothelial cancer:3.33e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 4284.3 lung: 1167.5 Cell line enhanced ASC TERT1: 24376.9;HSkMC: 11926.5;hTERT-HME1: 7509.7 +STAT1 ISGF-3, STAT91 ENSG00000115415 Signal transducer and activator of transcription 1 2 190964358-191020960 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000931, HPA000982, CAB004049 Approved Enhanced Nucleoplasm
Cytosol Renal cancer:1.22e-5 (unfavourable), Ovarian cancer:1.75e-4 (favourable), Pancreatic cancer:4.23e-4 (unfavourable) Expressed in all Expressed in all lymph node: 193.8 Expressed in all +GLS GLS1, KIAA0838 ENSG00000115419 Glutaminase 2 190880827-190965552 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036223 Enhanced Supported Mitochondria Endometrial cancer:3.45e-4 (unfavourable) Expressed in all Expressed in all kidney: 333.2 Expressed in all +PAPOLG FLJ12972 ENSG00000115421 Poly(A) polymerase gamma 2 60756230-60802085 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017795, HPA035349, HPA035350 Approved Enhanced Nucleoplasm Renal cancer:4.21e-4 (unfavourable) Expressed in all Mixed thyroid gland: 22.2 Expressed in all +DNAH6 Dnahc6, DNHL1, FLJ37357, HL-2 ENSG00000115423 Dynein axonemal heavy chain 6 2 84516455-84819589 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036391 Enhanced Mixed Tissue enhanced fallopian tube: 8.7;testis: 4.9 parathyroid gland: 3.2 Not detected +PECR HSA250303, SDR29C1, TERP ENSG00000115425 Peroxisomal trans-2-enoyl-CoA reductase 2 215996329-216082955 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021593, HPA022539 Enhanced Supported Peroxisomes Renal cancer:1.36e-5 (favourable) Expressed in all Expressed in all liver: 82.8 Mixed +UNC50 GMH1, UNCL, URP ENSG00000115446 Unc-50 inner nuclear membrane RNA binding protein 2 98608579-98618515 Predicted membrane proteins Evidence at protein level HPA027009 Approved Liver cancer:4.89e-5 (unfavourable), Breast cancer:4.79e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 106.2 Expressed in all +IGFBP2 IBP2 ENSG00000115457 Insulin like growth factor binding protein 2 2 216632828-216664436 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA077723 Approved Endoplasmic reticulum Renal cancer:2.22e-5 (unfavourable), Melanoma:2.43e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 279.9 Cell line enhanced ASC diff: 1479.2;HMC-1: 4500.9 +ELMOD3 DFNB88, FLJ21977, RBED1, RBM29 ENSG00000115459 ELMO domain containing 3 2 85354394-85391752 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA012126 Approved Approved Nucleoplasm
Mitochondria Renal cancer:1.09e-6 (unfavourable), Pancreatic cancer:6.16e-6 (favourable), Urothelial cancer:2.85e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 11.4 Expressed in all +IGFBP5 ENSG00000115461 Insulin like growth factor binding protein 5 2 216672105-216695525 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA059827 Approved Nuclear bodies
Golgi apparatus
Vesicles Endometrial cancer:1.78e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 2374.4;ovary: 1646.3 fallopian tube: 949.1 Cell line enhanced BJ: 704.3;BJ hTERT+: 1787.5;T-47d: 500.8;U-138 MG: 702.9 +USP34 KIAA0570, KIAA0729 ENSG00000115464 Ubiquitin specific peptidase 34 2 61187463-61470769 Enzymes, Predicted intracellular proteins Evidence at protein level HPA025815, HPA070764 Uncertain Approved Nucleus Expressed in all Expressed in all epididymis: 66.0 Expressed in all +EFHD1 FLJ13612 ENSG00000115468 EF-hand domain family member D1 2 232606057-232682781 Predicted intracellular proteins Evidence at protein level HPA049331, HPA056959 Enhanced Supported Nucleoli fibrillar center
Golgi apparatus Renal cancer:2.93e-7 (favourable) Expressed in all Tissue enhanced breast: 227.6 kidney: 177.3 Group enriched 7 BEWO: 121.1;RPTEC TERT1: 51.3;SK-BR-3: 225.6;T-47d: 222.0 +KCNJ13 Kir1.4, Kir7.1, LCA16 ENSG00000115474 Potassium voltage-gated channel subfamily J member 13 2 232766464-232776568 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Tissue enriched Group enriched 5 parathyroid gland: 25.8;small intestine: 112.2 thyroid gland: 12.5 Cell line enhanced U-2197: 1.2 +CCT4 Cctd ENSG00000115484 Chaperonin containing TCP1 subunit 4 2 61868089-61888804 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029349 Enhanced Supported Nucleoplasm
Cytosol Liver cancer:9.37e-12 (unfavourable), Breast cancer:2.03e-4 (unfavourable) Expressed in all Expressed in all testis: 133.6 Expressed in all +GGCX VKCFD1 ENSG00000115486 Gamma-glutamyl carboxylase 2 85544723-85561547 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA018284 Approved Endometrial cancer:1.82e-6 (unfavourable) Expressed in all Expressed in all liver: 61.3 Expressed in all +NEU2 SIAL2 ENSG00000115488 Neuraminidase 2 2 233032672-233035057 Enzymes, Predicted intracellular proteins Evidence at protein level CAB022336 Uncertain Not detected Tissue enriched 13 skin: 1.4 breast: 0.1 Not detected +EHBP1 KIAA0903, NACSIN ENSG00000115504 EH domain binding protein 1 2 62673851-63046487 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035468, HPA035469 Enhanced Supported Plasma membrane
Cytosol Urothelial cancer:1.95e-8 (unfavourable), Lung cancer:9.03e-4 (unfavourable) Expressed in all Expressed in all testis: 68.0 Expressed in all +OTX1 ENSG00000115507 Orthodenticle homeobox 1 2 63050057-63057836 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB012341, HPA052122 Approved Uncertain Nuclear speckles
Cytosol Mixed Tissue enhanced cerebral cortex: 1.7;skin: 6.1 prostate: 1.0 Cell line enriched 6 THP-1: 35.9 +TXNDC9 APACD ENSG00000115514 Thioredoxin domain containing 9 2 99318982-99340702 Predicted intracellular proteins Evidence at protein level HPA031844, HPA031845, HPA031846 Approved Enhanced Cytosol Liver cancer:9.63e-7 (unfavourable), Head and neck cancer:4.31e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 36.4 Expressed in all +COQ10B FLJ13448 ENSG00000115520 Coenzyme Q10B 2 197453423-197475308 Predicted intracellular proteins Evidence at protein level HPA046057 Approved Approved Cytosol Expressed in all Expressed in all adrenal gland: 49.7 Expressed in all +GNLY D2S69E, LAG-2, LAG2, NKG5, TLA519 ENSG00000115523 Granulysin 2 85685175-85698854 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB025186, HPA058021 Enhanced Endometrial cancer:3.48e-5 (favourable), Melanoma:6.60e-5 (favourable), Renal cancer:1.50e-4 (unfavourable), Urothelial cancer:8.07e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 152.4;endometrium: 113.5;spleen: 112.9 lung: 51.0 Not detected +SF3B1 Hsh155, Prp10, PRPF10, SAP155, SF3b155 ENSG00000115524 Splicing factor 3b subunit 1 2 197389784-197435091 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050275 Approved Enhanced Nuclear speckles Expressed in all Expressed in all endometrium: 348.2 Expressed in all +ST3GAL5 SIAT9, SIATGM3S, ST3GalV ENSG00000115525 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2 85837120-85905199 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034708, HPA040425, HPA068928 Uncertain Approved Vesicles Renal cancer:2.25e-7 (unfavourable), Urothelial cancer:4.48e-4 (favourable), Thyroid cancer:4.99e-4 (favourable) Expressed in all Tissue enhanced thyroid gland: 44.7 cerebral cortex: 40.7 Cell line enhanced AN3-CA: 50.3;RT4: 37.4 +CHST10 HNK-1ST ENSG00000115526 Carbohydrate sulfotransferase 10 2 100391860-100417656 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012884, HPA051545 Approved Approved Cytosol Pancreatic cancer:4.05e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 46.4 endometrium: 19.4 Mixed +PDCL3 VIAF1 ENSG00000115539 Phosducin like 3 2 100562690-100576735 Predicted intracellular proteins Evidence at protein level HPA018469, HPA027094 Approved Enhanced Nucleus
Cytosol Renal cancer:2.55e-5 (unfavourable), Liver cancer:6.07e-5 (unfavourable), Urothelial cancer:4.23e-4 (favourable) Expressed in all Expressed in all smooth muscle: 40.3 Expressed in all +MOB4 2C4D, CGI-95, DKFZP564M112, MOB3, MOBKL3, PHOCN, PREI3 ENSG00000115540 MOB family member 4, phocein 2 197515571-197553699 Predicted intracellular proteins Evidence at protein level CAB034082, HPA044125 Approved Renal cancer:4.68e-4 (unfavourable), Liver cancer:8.29e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 79.6 Expressed in all +HSPE1 CPN10, EPF, GroES, HSP10 ENSG00000115541 Heat shock protein family E (Hsp10) member 1 2 197499994-197503457 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017366, HPA038755, HPA048272 Supported Expressed in all Expressed in all adrenal gland: 650.8 Expressed in all +KDM3A JHMD2A, JMJD1, JMJD1A, KIAA0742, TSGA ENSG00000115548 Lysine demethylase 3A 2 86440647-86492716 Predicted intracellular proteins Evidence at protein level HPA055543, HPA065162 Enhanced Nucleoplasm Liver cancer:2.15e-6 (unfavourable), Renal cancer:5.25e-4 (unfavourable) Expressed in all Expressed in all testis: 93.0 Expressed in all +PLCD4 ENSG00000115556 Phospholipase C delta 4 2 218607765-218637184 Enzymes, Predicted intracellular proteins Evidence at protein level CAB009914, HPA038139, HPA038140 Enhanced Approved Nuclear membrane
Plasma membrane
Cytosol Mixed Tissue enhanced skeletal muscle: 38.4 testis: 9.7 Cell line enhanced SH-SY5Y: 21.8 +CHMP3 CGI-149, NEDF, VPS24 ENSG00000115561 Charged multivesicular body protein 3 2 86503431-86563479 Predicted intracellular proteins Evidence at protein level HPA015673, HPA073383 Supported Liver cancer:3.92e-5 (unfavourable), Renal cancer:5.32e-4 (favourable), Pancreatic cancer:7.39e-4 (unfavourable) Expressed in all Expressed in all endometrium: 114.0 Expressed in all +ZNF142 KIAA0236, pHZ-49 ENSG00000115568 Zinc finger protein 142 2 218637916-218659655 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049594 Uncertain Approved Nucleus
Nucleoli fibrillar center Liver cancer:1.35e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 14.9 Expressed in all +IL1R2 CD121b, IL1RB ENSG00000115590 Interleukin 1 receptor type 2 2 101991844-102028544 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA027597, HPA027598 Uncertain Renal cancer:5.58e-12 (unfavourable) Mixed Mixed appendix: 50.3 Cell line enriched 24 HDLM-2: 436.8 +PRKAG3 ENSG00000115592 Protein kinase AMP-activated non-catalytic subunit gamma 3 2 218822383-218832086 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 18 skeletal muscle: 23.9 esophagus: 1.3 Not detected +SMYD1 BOP, KMT3D, ZMYND22 ENSG00000115593 SET and MYND domain containing 1 2 88067780-88113387 Enzymes, Predicted intracellular proteins Evidence at protein level HPA062282 Enhanced Tissue enhanced Group enriched 9 heart muscle: 107.0;skeletal muscle: 170.8;smooth muscle: 38.5 parathyroid gland: 11.6 Not detected +IL1R1 CD121A, D2S1473, IL1R, IL1RA ENSG00000115594 Interleukin 1 receptor type 1 2 102064544-102179874 Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005823, CAB007779, HPA029560 Approved Renal cancer:6.92e-6 (unfavourable) Expressed in all Expressed in all cervix, uterine: 246.0 Cell line enhanced ASC diff: 431.3;ASC TERT1: 195.1;HHSteC: 165.4;HSkMC: 562.6 +WNT6 ENSG00000115596 Wnt family member 6 2 218859821-218874233 Predicted secreted proteins Evidence at protein level HPA070759 Approved Tissue enhanced Tissue enhanced placenta: 2.9 spleen: 1.5 Cell line enriched 6 BEWO: 33.5 +IL1RL2 IL1R-rp2, IL1RRP2 ENSG00000115598 Interleukin 1 receptor like 2 2 102186973-102240002 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015485 Uncertain Mixed Tissue enhanced skin: 15.5 parathyroid gland: 8.5 Cell line enhanced A-431: 7.2;ASC TERT1: 3.6;HaCaT: 3.3;HSkMC: 3.1 +IL1RL1 DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1 ENSG00000115602 Interleukin 1 receptor like 1 2 102311502-102352037 Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007406, HPA007917 Uncertain Approved Vesicles Tissue enhanced Tissue enriched 12 placenta: 289.6 gallbladder: 23.7 Group enriched 6 HHSteC: 206.0;HMC-1: 327.3;HUVEC TERT2: 154.2 +IL18R1 CD218a, IL-1Rrp, IL1RRP ENSG00000115604 Interleukin 18 receptor 1 2 102311529-102398775 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007615 Approved Approved Mitochondria Renal cancer:4.52e-4 (unfavourable) Mixed Mixed placenta: 14.4 Cell line enhanced HDLM-2: 28.1;HHSteC: 51.3;HMC-1: 36.8;U-937: 54.3 +IL18RAP AcPL, CD218b ENSG00000115607 Interleukin 18 receptor accessory protein 2 102418689-102452565 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025270 Enhanced Mixed Tissue enhanced bone marrow: 70.9 appendix: 16.9 Cell line enriched 10 U-937: 42.2 +SLC9A2 NHE2 ENSG00000115616 Solute carrier family 9 member A2 2 102619707-102711318 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA035121, HPA035122 Approved Supported Cell Junctions Mixed Tissue enhanced colon: 20.5;rectum: 23.3;stomach: 25.7 testis: 10.7 Cell line enhanced A-431: 8.9;RT4: 13.9;SK-BR-3: 11.4;T-47d: 18.0 +FHL2 DRAL, SLIM3 ENSG00000115641 Four and a half LIM domains 2 2 105357712-105438513 Predicted intracellular proteins Evidence at protein level HPA005922, HPA006028, CAB008368 Enhanced Enhanced Actin filaments
Focal adhesion sites Renal cancer:6.42e-5 (unfavourable), Head and neck cancer:2.01e-4 (unfavourable) Expressed in all Expressed in all ovary: 659.3 Mixed +MLPH exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a ENSG00000115648 Melanophilin 2 237485428-237555318 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA014685 Uncertain Endometrial cancer:5.14e-6 (favourable), Renal cancer:1.50e-4 (unfavourable) Mixed Mixed prostate: 97.9 Cell line enhanced MCF7: 192.8;SK-BR-3: 174.6;SK-MEL-30: 137.5;U-87 MG: 230.5 +CNPPD1 C2orf24, CGI-57 ENSG00000115649 Cyclin Pas1/PHO80 domain containing 1 2 219171897-219178106 Predicted membrane proteins Evidence at transcript level HPA049303 Uncertain Renal cancer:1.62e-10 (favourable), Liver cancer:2.04e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 88.2 Expressed in all +UXS1 FLJ23591, SDR6E1, UGD ENSG00000115652 UDP-glucuronate decarboxylase 1 2 106093303-106194339 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008825 Uncertain Liver cancer:1.38e-4 (unfavourable), Head and neck cancer:5.45e-4 (unfavourable), Ovarian cancer:7.94e-4 (favourable) Expressed in all Expressed in all placenta: 76.1 Expressed in all +ABCB6 EST45597, MTABC3, umat ENSG00000115657 ATP binding cassette subfamily B member 6 (Langereis blood group) 2 219209768-219218990 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046723, HPA058011 Approved Enhanced Nucleoplasm
Golgi apparatus
Plasma membrane
Mitochondria
Cytosol Renal cancer:1.52e-7 (unfavourable), Liver cancer:9.45e-7 (unfavourable) Expressed in all Expressed in all testis: 32.7 Mixed +STK16 MPSK, PKL12 ENSG00000115661 Serine/threonine kinase 16 2 219245455-219250337 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029450 Approved Approved Cytosol Endometrial cancer:6.09e-4 (favourable) Expressed in all Expressed in all testis,thyroid gland: 28.6 Expressed in all +SLC5A7 CHT1, hCHT ENSG00000115665 Solute carrier family 5 member 7 2 107986523-108013994 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046105 Approved Nuclear bodies
Cell Junctions
Intermediate filaments Tissue enhanced Mixed thyroid gland: 2.0 Group enriched 21 RT4: 2.9;SCLC-21H: 1.2 +HDLBP HBP, VGL ENSG00000115677 High density lipoprotein binding protein 2 241227264-241317061 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004189, CAB026457 Supported Supported Cytosol Liver cancer:2.58e-5 (unfavourable), Thyroid cancer:6.39e-5 (unfavourable), Urothelial cancer:4.12e-4 (unfavourable) Expressed in all Expressed in all testis: 364.6 Expressed in all +PPP1R7 sds22 ENSG00000115685 Protein phosphatase 1 regulatory subunit 7 2 241149576-241183652 Predicted intracellular proteins Evidence at protein level HPA034500, HPA034501 Supported Approved Nucleoli Expressed in all Expressed in all testis: 287.5 Expressed in all +PASK KIAA0135, PASKIN, STK37 ENSG00000115687 PAS domain containing serine/threonine kinase 2 241106099-241150264 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016450, HPA021079 Uncertain Supported Cytosol Expressed in all Tissue enhanced testis: 25.5 prostate: 16.3 Mixed +STK25 SOK1, YSK1 ENSG00000115694 Serine/threonine kinase 25 2 241492674-241509730 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047147 Uncertain Liver cancer:3.91e-8 (unfavourable), Colorectal cancer:6.03e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 168.2 Expressed in all +TPO TPX ENSG00000115705 Thyroid peroxidase 2 1374223-1543711 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007987, CAB009587 Enhanced Tissue enriched Tissue enriched 103 thyroid gland: 1817.4 spleen: 17.6 Cell line enhanced Karpas-707: 6.9;RPMI-8226: 2.9 +PROC ENSG00000115718 Protein C, inactivator of coagulation factors Va and VIIIa 2 127418427-127429246 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005550, CAB016721, CAB016792 Supported Tissue enriched Tissue enriched 12 liver: 140.4 kidney: 12.0 Cell line enriched 12 Hep G2: 105.5 +ID2 bHLHb26, GIG8 ENSG00000115738 Inhibitor of DNA binding 2, HLH protein 2 8678845-8684453 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027612 Approved Nucleoplasm
Nuclear bodies
Centrosome Head and neck cancer:9.95e-4 (favourable) Expressed in all Tissue enriched 6 parathyroid gland: 1985.4 thyroid gland: 359.5 Cell line enhanced HDLM-2: 675.4;HEK 293: 418.6 +TAF1B RAF1B, RAFI63, SL1, TAFI63 ENSG00000115750 TATA-box binding protein associated factor, RNA polymerase I subunit B 2 9843354-9934416 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA071254 Supported Nucleus
Nucleoli Liver cancer:6.94e-7 (unfavourable), Colorectal cancer:8.58e-5 (favourable), Renal cancer:8.55e-4 (favourable) Expressed in all Mixed parathyroid gland: 23.9 Expressed in all +HPCAL1 BDR1, HLP2, VILIP-3 ENSG00000115756 Hippocalcin like 1 2 10302889-10427617 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043245 Approved Renal cancer:4.39e-6 (unfavourable), Glioma:5.68e-5 (unfavourable) Expressed in all Expressed in all lung: 80.5 Expressed in all +ODC1 ODC ENSG00000115758 Ornithine decarboxylase 1 2 10439968-10448504 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001536, CAB035996 Approved Approved Plasma membrane
Cytosol Liver cancer:3.07e-5 (unfavourable) Expressed in all Expressed in all testis: 242.0 Expressed in all +BIRC6 BRUCE ENSG00000115760 Baculoviral IAP repeat containing 6 2 32357028-32618899 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA074409, HPA074738 Supported Golgi apparatus
Vesicles
Mitotic spindle Expressed in all Mixed parathyroid gland: 31.4 Expressed in all +NOL10 FLJ14075, PQBP5 ENSG00000115761 Nucleolar protein 10 2 10570766-10689987 Predicted intracellular proteins Evidence at protein level HPA035286, HPA043075 Approved Supported Nucleoli Liver cancer:1.43e-7 (unfavourable), Endometrial cancer:2.92e-5 (unfavourable), Renal cancer:7.51e-5 (unfavourable) Expressed in all Expressed in all testis: 27.6 Expressed in all +PLEKHB2 EVT2, FLJ20783 ENSG00000115762 Pleckstrin homology domain containing B2 2 131104847-131353709 Predicted intracellular proteins Evidence at protein level HPA075014 Approved Renal cancer:1.72e-8 (favourable), Liver cancer:1.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 125.3 Expressed in all +GORASP2 GOLPH6, GRASP55, GRS2 ENSG00000115806 Golgi reassembly stacking protein 2 2 170928464-170967129 Predicted intracellular proteins Evidence at protein level HPA035274, HPA035275, CAB075758 Enhanced Enhanced Golgi apparatus Renal cancer:1.38e-8 (unfavourable), Head and neck cancer:7.32e-4 (unfavourable) Expressed in all Expressed in all epididymis: 42.2 Expressed in all +STRN PPP2R6A, STRN1 ENSG00000115808 Striatin 2 36843640-36966472 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA017286 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.27e-4 (favourable) Expressed in all Expressed in all esophagus: 23.8 Expressed in all +CEBPZ CBF2, CTF2 ENSG00000115816 CCAAT/enhancer binding protein zeta 2 37201612-37231713 Predicted intracellular proteins Evidence at protein level HPA052065 Uncertain Approved Nucleus
Vesicles Liver cancer:2.94e-5 (unfavourable), Endometrial cancer:5.07e-4 (unfavourable), Pancreatic cancer:8.13e-4 (unfavourable) Expressed in all Expressed in all testis: 67.3 Expressed in all +PRKD3 EPK2, PRKCN ENSG00000115825 Protein kinase D3 2 37250502-37324808 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029529 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:3.47e-4 (unfavourable), Colorectal cancer:4.84e-4 (favourable) Expressed in all Expressed in all testis: 44.4 Expressed in all +DCAF17 C2orf37, FLJ13096 ENSG00000115827 DDB1 and CUL4 associated factor 17 2 171434217-171485052 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053339, HPA055040 Uncertain Supported Nucleoplasm Thyroid cancer:7.10e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 17.1 Expressed in all +QPCT GCT, QC ENSG00000115828 Glutaminyl-peptide cyclotransferase 2 37344574-37373322 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008406 Enhanced Approved Cytosol Expressed in all Tissue enhanced adrenal gland: 158.9;epididymis: 121.6 skin: 41.1 Cell line enhanced SCLC-21H: 130.6;SK-MEL-30: 299.7;U-266/84: 218.7 +RAB3GAP1 KIAA0066, RAB3GAP, RAB3GAP130, WARBM1 ENSG00000115839 RAB3 GTPase activating protein catalytic subunit 1 2 135052265-135176394 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034494, HPA034495 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:2.96e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 57.5 Expressed in all +SLC25A12 Aralar ENSG00000115840 Solute carrier family 25 member 12 2 171784370-171999859 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA035333, HPA035334 Enhanced Uncertain Nuclear speckles
Cytosol Renal cancer:2.91e-8 (favourable), Endometrial cancer:7.86e-4 (unfavourable) Expressed in all Mixed skeletal muscle: 55.3 Mixed +RMDN2 FAM82A, FAM82A1, FLJ32954, RMD2 ENSG00000115841 Regulator of microtubule dynamics 2 2 37923187-38067142 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034705, HPA034706 Approved Supported Golgi apparatus
Mitotic spindle
Cytosol Lung cancer:2.63e-4 (favourable) Mixed Expressed in all adrenal gland: 68.9 Mixed +DLX2 TES-1 ENSG00000115844 Distal-less homeobox 2 2 172099439-172102900 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056965 Approved Nuclear speckles Mixed Not detected cerebral cortex: 0.8 Group enriched 11 AN3-CA: 73.7;HEK 293: 46.5 +LCT ENSG00000115850 Lactase 2 135787840-135837180 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Not detected Group enriched 631 duodenum: 223.1;small intestine: 142.8 appendix,lymph node: 0.2 Cell line enhanced MOLT-4: 3.9;RPMI-8226: 6.7 +DARS ENSG00000115866 Aspartyl-tRNA synthetase 2 135906677-135986100 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020451, HPA029804, HPA029805 Enhanced Enhanced Cytosol Liver cancer:2.39e-6 (unfavourable), Renal cancer:1.24e-5 (unfavourable), Pancreatic cancer:6.54e-4 (unfavourable), Melanoma:7.57e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 91.0 Expressed in all +SRSF7 9G8, AAG3, HSSG1, RBM37, SFRS7, ZCCHC20, ZCRB2 ENSG00000115875 Serine and arginine rich splicing factor 7 2 38743599-38751494 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043850, HPA056926 Enhanced Enhanced Nucleoplasm Renal cancer:3.18e-8 (unfavourable), Liver cancer:2.90e-5 (unfavourable) Expressed in all Expressed in all testis: 99.7 Expressed in all +SDC1 CD138, SDC, SYND1, syndecan ENSG00000115884 Syndecan 1 2 20200797-20225433 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB002424, HPA006185 Approved Supported Focal adhesion sites Breast cancer:2.22e-4 (unfavourable), Glioma:8.05e-4 (unfavourable) Expressed in all Tissue enhanced esophagus: 250.7;skin: 287.9 liver: 144.7 Cell line enhanced U-266/84: 739.8 +PLCL1 PLC-L, PLCE, PLCL, PPP1R127, PRIP ENSG00000115896 Phospholipase C like 1 2 197804702-198572581 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA031849 Enhanced Renal cancer:3.91e-7 (favourable) Mixed Mixed kidney: 34.3 Cell line enhanced HUVEC TERT2: 7.3;K-562: 13.7;Karpas-707: 7.9;MOLT-4: 8.6 +SLC1A4 ASCT1, SATT ENSG00000115902 Solute carrier family 1 member 4 2 64988477-65023865 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA034963, HPA034964 Approved Supported Centrosome Liver cancer:4.23e-5 (unfavourable), Cervical cancer:3.59e-4 (favourable), Renal cancer:4.87e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 79.1 Expressed in all +SOS1 GF1, GINGF, HGF ENSG00000115904 SOS Ras/Rac guanine nucleotide exchange factor 1 2 38981396-39124345 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB005396, HPA012613 Uncertain Uncertain Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all parathyroid gland: 41.0 Expressed in all +KYNU ENSG00000115919 Kynureninase 2 142877498-143055832 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA031686 Enhanced Supported Nucleoplasm
Cytosol Mixed Mixed liver: 45.9 Cell line enhanced A549: 168.9;HeLa: 138.9;hTEC/SVTERT24-B: 106.9;SiHa: 109.4;U-87 MG: 309.1 +WIPF1 WASPIP, WIP ENSG00000115935 WAS/WASL interacting protein family member 1 2 174559572-174682916 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003739, CAB009737, HPA070706 Enhanced Approved Plasma membrane
Cytosol Renal cancer:1.14e-4 (unfavourable) Expressed in all Expressed in all lymph node: 157.5 Cell line enhanced Karpas-707: 220.1 +ORC2 ORC2L ENSG00000115942 Origin recognition complex subunit 2 2 200908973-200963680 Predicted intracellular proteins Evidence at protein level CAB003693, HPA073881 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:1.97e-4 (unfavourable), Melanoma:8.42e-4 (unfavourable) Expressed in all Mixed testis: 38.1 Expressed in all +COX7A2L COX7AR, COX7RP, EB1, SIG81 ENSG00000115944 Cytochrome c oxidase subunit 7A2 like 2 42333546-42425088 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059124, CAB073545 Enhanced Nucleoli
Mitochondria Liver cancer:4.13e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 254.6 Expressed in all +PNO1 KHRBP1, RRP20 ENSG00000115946 Partner of NOB1 homolog 2 68157844-68176238 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056928 Supported Nucleus
Nucleoli Liver cancer:3.04e-8 (unfavourable), Endometrial cancer:1.12e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 20.8 Expressed in all +ORC4 HsORC4, ORC4L, Orc4p ENSG00000115947 Origin recognition complex subunit 4 2 147930397-148021604 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015124, HPA064562 Approved Supported Nucleus
Nucleoli Liver cancer:4.98e-8 (unfavourable), Renal cancer:4.10e-6 (favourable), Endometrial cancer:7.27e-4 (unfavourable) Expressed in all Expressed in all testis: 28.5 Expressed in all +PLEK P47 ENSG00000115956 Pleckstrin 2 68365173-68397453 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031838, HPA057341 Enhanced Approved Nucleoli Renal cancer:1.95e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 371.1 lymph node: 142.4 Cell line enhanced HEL: 475.7;HMC-1: 170.8;THP-1: 139.2;U-937: 256.0 +RND3 ARHE, Rho8, RhoE ENSG00000115963 Rho family GTPase 3 2 150468195-150539011 Predicted intracellular proteins Evidence at protein level HPA060504 Uncertain Renal cancer:1.78e-4 (unfavourable) Expressed in all Mixed esophagus: 169.5 Cell line enhanced BJ: 570.2;BJ hTERT+: 1071.0;hTERT-HME1: 496.5 +ATF2 CRE-BP1, CREB2, HB16, TREB7 ENSG00000115966 Activating transcription factor 2 2 175072250-175168382 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003769, HPA022134 Supported Enhanced Nucleoplasm Liver cancer:7.08e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 54.0 Expressed in all +THADA ARMC13, FLJ21877, GITA, KIAA1767 ENSG00000115970 THADA, armadillo repeat containing 2 43230836-43596046 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035191, HPA035192 Uncertain Approved Cytosol Liver cancer:6.48e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 26.8 Mixed +AAK1 DKFZp686K16132, KIAA1048 ENSG00000115977 AP2 associated kinase 1 2 69457997-69674349 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017931, HPA020289 Enhanced Supported Plasma membrane
Cytosol Ovarian cancer:3.19e-4 (unfavourable) Expressed in all Tissue enriched 7 parathyroid gland: 389.6 thyroid gland: 59.4 Expressed in all +TRAK2 ALS2CR3, CALS-C, GRIF-1, KIAA0549, MILT2, OIP98 ENSG00000115993 Trafficking kinesin protein 2 2 201377207-201451579 Predicted intracellular proteins Evidence at protein level HPA015827, HPA062163 Uncertain Approved Nucleoplasm
Nuclear bodies
Vesicles Renal cancer:7.42e-5 (favourable) Expressed in all Expressed in all thyroid gland: 52.1 Expressed in all +C2orf42 FLJ20558 ENSG00000115998 Chromosome 2 open reading frame 42 2 70149880-70248615 Predicted intracellular proteins Evidence at protein level HPA031840, HPA031841, HPA031842 Enhanced Enhanced Nucleus Pancreatic cancer:5.94e-5 (favourable) Expressed in all Tissue enriched 6 testis: 109.7 fallopian tube: 18.7 Expressed in all +TIA1 ENSG00000116001 TIA1 cytotoxic granule associated RNA binding protein 2 70209444-70248660 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056961 Supported Nucleoplasm
Cytosol Renal cancer:8.05e-7 (unfavourable), Urothelial cancer:1.02e-5 (favourable), Lung cancer:6.79e-5 (favourable) Expressed in all Expressed in all endometrium: 113.1 Expressed in all +PCYOX1 KIAA0908, PCL1 ENSG00000116005 Prenylcysteine oxidase 1 2 70257386-70281191 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035193 Approved Renal cancer:1.89e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 141.1 Expressed in all +KISS1R AXOR12, GPR54, HOT7T175 ENSG00000116014 KISS1 receptor 19 917287-921015 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA071913 Supported Vesicles
Plasma membrane Renal cancer:3.33e-6 (unfavourable) Tissue enhanced Tissue enriched 5 cerebral cortex: 1.2 appendix,lymph node,placenta: 0.2 Cell line enhanced K-562: 14.0;RPMI-8226: 26.1;SCLC-21H: 8.9;SH-SY5Y: 21.3 +EPAS1 bHLHe73, HIF2A, HLF, MOP2, PASD2 ENSG00000116016 Endothelial PAS domain protein 1 2 46293667-46386703 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031200, HPA069697 Supported Nucleoplasm
Cytosol Renal cancer:2.63e-4 (favourable) Expressed in all Expressed in all placenta: 642.0 Cell line enhanced U-138 MG: 279.3 +ARID3A BRIGHT, DRIL1 ENSG00000116017 AT-rich interaction domain 3A 19 925781-975934 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004793, HPA076330 Enhanced Supported Nucleoplasm
Vesicles
Cytosol Pancreatic cancer:1.95e-5 (favourable), Renal cancer:3.22e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 33.4 testis: 9.7 Cell line enhanced BEWO: 199.1;K-562: 85.1 +SUMO1 GMP1, OFC10, PIC1, SMT3C, SMT3H3, SUMO-1, UBL1 ENSG00000116030 Small ubiquitin-like modifier 1 2 202206180-202238608 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004269, HPA056956 Supported Supported Nucleus
Nuclear membrane
Nucleoli
Nuclear bodies Ovarian cancer:7.93e-4 (favourable) Expressed in all Expressed in all thyroid gland: 171.0 Expressed in all +CD207 CLEC4K, Langerin ENSG00000116031 CD207 molecule 2 70830214-70835822 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level CAB002222, HPA011216 Enhanced Uncertain Cytosol Mixed Tissue enriched 5 skin: 104.0 esophagus: 19.4 Cell line enhanced AN3-CA: 8.3;HAP1: 2.2;SH-SY5Y: 1.3;T-47d: 1.5 +GRIN3B GluN3B ENSG00000116032 Glutamate ionotropic receptor NMDA type subunit 3B 19 1000419-1009732 FDA approved drug targets, Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced fallopian tube: 2.1;spleen: 1.2 lung: 0.7 Cell line enhanced U-266/70: 2.6 +VAX2 DRES93 ENSG00000116035 Ventral anterior homeobox 2 2 70900590-70933446 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009708 Approved Nuclear speckles Mixed Tissue enhanced cerebral cortex: 3.2 adipose tissue,adrenal gland,breast,endometrium: 0.7 Cell line enhanced SH-SY5Y: 7.0 +ATP6V1B1 ATP6B1, RTA1B, VATB, Vma2, VPP3 ENSG00000116039 ATPase H+ transporting V1 subunit B1 2 70935882-70965406 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB009523, HPA031847 Enhanced Approved Nucleus
Nuclear membrane Group enriched Group enriched 10 breast: 16.1;cervix, uterine: 47.9;fallopian tube: 21.1;kidney: 64.8;placenta: 27.8;salivary gland: 66.5 skin: 4.2 Group enriched 6 BEWO: 20.0;HaCaT: 17.4;SK-BR-3: 34.9 +NFE2L2 NRF2 ENSG00000116044 Nuclear factor, erythroid 2 like 2 2 177227595-177392697 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002990, CAB020317, HPA043438 Enhanced Approved Nucleus
Plasma membrane
Cytosol Renal cancer:2.26e-4 (favourable) Expressed in all Expressed in all esophagus: 267.1 Expressed in all +MSH6 GTBP ENSG00000116062 MutS homolog 6 2 47695530-47810101 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009091, HPA028376, HPA028446, CAB070870 Enhanced Supported Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:1.06e-7 (unfavourable), Endometrial cancer:1.34e-4 (unfavourable), Liver cancer:7.86e-4 (unfavourable) Expressed in all Expressed in all ovary: 74.5 Expressed in all +PLEKHA3 FAPP1 ENSG00000116095 Pleckstrin homology domain containing A3 2 178480468-178516462 Predicted intracellular proteins Evidence at protein level HPA034496, HPA034497 Approved Enhanced Golgi apparatus Expressed in all Mixed testis: 15.1 Mixed +SPR SDR38C1 ENSG00000116096 Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 2 72887360-72892158 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039505 Uncertain Supported Nucleoplasm
Cytosol Expressed in all Mixed parathyroid gland: 49.9 Mixed +EPHA4 Hek8, TYRO1 ENSG00000116106 EPH receptor A4 2 221418027-221574202 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB028368 Enhanced Renal cancer:5.67e-4 (favourable), Ovarian cancer:9.56e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 41.6 testis: 22.2 Cell line enhanced AF22: 77.5;CACO-2: 49.0;U-2197: 35.7 +PARD3B ALS2CR19, PAR3beta, Par3L ENSG00000116117 Par-3 family cell polarity regulator beta 2 204545793-205620162 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035283 Approved Supported Nucleoplasm
Nuclear bodies
Cell Junctions Renal cancer:2.67e-10 (favourable) Expressed in all Mixed parathyroid gland: 13.4 Cell line enhanced ASC diff: 12.1 +FARSB FARSLB, FRSB, PheHB ENSG00000116120 Phenylalanyl-tRNA synthetase beta subunit 2 222570536-222656337 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036677, HPA036678, HPA061398 Enhanced Supported Nucleus
Cytosol Liver cancer:6.45e-10 (unfavourable), Renal cancer:3.21e-5 (unfavourable), Urothelial cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all testis: 34.4 Expressed in all +ALMS1 KIAA0328 ENSG00000116127 ALMS1, centrosome and basal body associated protein 2 73385758-73610793 Predicted intracellular proteins Evidence at protein level HPA043200 Enhanced Approved Cytosol Expressed in all Tissue enhanced testis: 32.5 ovary: 9.1 Cell line enhanced RH-30: 26.7 +BCL9 ENSG00000116128 B-cell CLL/lymphoma 9 1 147541412-147626216 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020274 Enhanced Approved Nucleoplasm
Nuclear bodies Liver cancer:6.74e-4 (unfavourable) Expressed in all Mixed fallopian tube: 26.5 Cell line enhanced NTERA-2: 42.4 +PRRX1 PHOX1, PMX1 ENSG00000116132 Paired related homeobox 1 1 170662728-170739419 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051084, HPA063566 Uncertain Supported Nucleoplasm Renal cancer:6.60e-10 (unfavourable) Mixed Mixed cervix, uterine: 135.8 Cell line enhanced ASC diff: 240.8;ASC TERT1: 194.6;BJ hTERT+: 165.0;U-138 MG: 137.1;U-2197: 125.0 +DHCR24 DCE, KIAA0018, seladin-1 ENSG00000116133 24-dehydrocholesterol reductase 1 54849633-54887218 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017981, CAB037247, HPA063005 Approved Endometrial cancer:1.05e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 1094.6 Mixed +DNAJC16 KIAA0962 ENSG00000116138 DnaJ heat shock protein family (Hsp40) member C16 1 15526813-15592379 Predicted membrane proteins Evidence at protein level HPA043643 Approved Approved Vesicles Colorectal cancer:6.77e-4 (favourable), Renal cancer:7.24e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 16.8 Expressed in all +MARK1 MARK, PAR-1C ENSG00000116141 Microtubule affinity regulating kinase 1 1 220528183-220664461 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007421, HPA008061 Uncertain Pancreatic cancer:2.23e-5 (favourable), Melanoma:2.63e-4 (unfavourable) Mixed Mixed cerebral cortex: 21.1 Cell line enhanced RT4: 50.7 +TNR ENSG00000116147 Tenascin R 1 175315194-175743770 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB022343, HPA027134, HPA027150, HPA029859 Enhanced Tissue enriched Tissue enriched 38 cerebral cortex: 70.6 adrenal gland: 1.8 Cell line enhanced SH-SY5Y: 1.9;U-937: 1.1 +MORN1 FLJ13941 ENSG00000116151 MORN repeat containing 1 1 2321253-2391707 Predicted intracellular proteins Evidence at transcript level HPA005858, HPA070703 Uncertain Approved Nucleus
Mitochondria Mixed Tissue enhanced fallopian tube: 17.7 testis: 12.1 Mixed +GPX7 FLJ14777, GPX6, NPGPx ENSG00000116157 Glutathione peroxidase 7 1 52602372-52609051 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA025829 Approved Nucleoli Renal cancer:2.26e-5 (unfavourable) Expressed in all Expressed in all placenta: 42.1 Cell line enhanced REH: 69.6;RPMI-8226: 89.3;THP-1: 68.1 +CACYBP S100A6BP, SIP ENSG00000116161 Calcyclin binding protein 1 174999163-175011715 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025753, HPA057038 Approved Enhanced Nucleoplasm
Cytosol Liver cancer:1.12e-6 (unfavourable), Ovarian cancer:1.39e-5 (favourable), Renal cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 60.7 Expressed in all +SCP2 ENSG00000116171 Sterol carrier protein 2 1 52927229-53051703 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027101, HPA027135, HPA027317 Supported Enhanced Peroxisomes Renal cancer:7.85e-8 (favourable), Colorectal cancer:7.05e-5 (favourable) Expressed in all Expressed in all liver: 601.5 Expressed in all +TPSG1 PRSS31, TMT ENSG00000116176 Tryptase gamma 1 16 1221651-1225257 Enzymes, Predicted membrane proteins Evidence at protein level HPA060458 Enhanced Renal cancer:1.76e-8 (unfavourable) Tissue enhanced Tissue enhanced colon: 14.6;duodenum: 14.3;rectum: 9.5;small intestine: 10.5 ovary: 2.5 Group enriched 8 HMC-1: 20.4;MCF7: 6.0 +PAPPA2 PAPP-A2, PAPPE, PLAC3 ENSG00000116183 Pappalysin 2 1 176463171-176845605 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018412, HPA018430 Enhanced Approved Endoplasmic reticulum
Vesicles Mixed Tissue enriched 8 placenta: 82.7 cervix, uterine: 10.8 Cell line enriched 6 U-87 MG: 19.4 +RALGPS2 FLJ10244, FLJ25604, KIAA0351 ENSG00000116191 Ral GEF with PH domain and SH3 binding motif 2 1 178725147-178921841 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027143, HPA028328 Enhanced Uncertain Nucleoplasm
Cytosol Expressed in all Tissue enhanced testis: 138.2 lymph node: 62.7 Cell line enhanced U-266/84: 172.2;U-698: 134.0 +ANGPTL1 ANG3, ANGPT3, AngY, ARP1 ENSG00000116194 Angiopoietin like 1 1 178849705-178871052 Predicted secreted proteins Evidence at protein level HPA009976 Approved Renal cancer:5.11e-4 (favourable), Liver cancer:8.73e-4 (favourable) Mixed Tissue enhanced placenta: 190.2 smooth muscle: 96.7 Group enriched 18 ASC diff: 102.1;ASC TERT1: 41.7;HHSteC: 54.1;HSkMC: 106.7 +CEP104 CFAP256, GlyBP, JBTS25, KIAA0562, ROC22, RP1-286D6.4 ENSG00000116198 Centrosomal protein 104 1 3812081-3857214 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA010126 Approved Renal cancer:1.70e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 36.2 Expressed in all +FAM20B GXK1, KIAA0475 ENSG00000116199 FAM20B, glycosaminoglycan xylosylkinase 1 179025804-179076562 Predicted intracellular proteins Evidence at protein level HPA007409 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 37.8 Expressed in all +TCEANC2 C1orf83, FLJ32112 ENSG00000116205 Transcription elongation factor A N-terminal and central domain containing 2 1 54053587-54112519 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046918 Uncertain Approved Nucleoplasm
Vesicles Expressed in all Mixed testis: 12.5 Expressed in all +TMEM59 C1orf8, HSPC001 ENSG00000116209 Transmembrane protein 59 1 54026681-54053504 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Expressed in all Expressed in all fallopian tube: 650.0 Expressed in all +LRRC42 MGC8974 ENSG00000116212 Leucine rich repeat containing 42 1 53946077-53968168 Predicted intracellular proteins Evidence at protein level HPA047458, HPA050537, HPA064581 Uncertain Enhanced Nucleoplasm Liver cancer:3.88e-5 (unfavourable), Lung cancer:6.02e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 39.1 Expressed in all +WRAP73 WDR8 ENSG00000116213 WD repeat containing, antisense to TP73 1 3630767-3652761 Predicted intracellular proteins Evidence at protein level HPA026893 Uncertain Approved Nucleoplasm
Cell Junctions Liver cancer:1.37e-4 (unfavourable), Renal cancer:1.42e-4 (unfavourable), Pancreatic cancer:3.49e-4 (favourable) Expressed in all Expressed in all lymph node: 20.4 Expressed in all +NPHS2 PDCN, SRN1 ENSG00000116218 NPHS2, podocin 1 179550539-179575952 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB037267, HPA049486 Enhanced Not detected Tissue enriched 87 kidney: 93.6 testis: 1.0 Cell line enriched 12 NTERA-2: 1.1 +MRPL37 MRP-L2, RPML2 ENSG00000116221 Mitochondrial ribosomal protein L37 1 54184041-54225464 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA025767, HPA025826, HPA025951 Enhanced Supported Mitochondria Liver cancer:6.45e-5 (unfavourable), Colorectal cancer:6.99e-4 (favourable), Stomach cancer:9.25e-4 (favourable) Expressed in all Expressed in all fallopian tube: 61.8 Expressed in all +ICMT HSTE14, PCCMT, PPMT ENSG00000116237 Isoprenylcysteine carboxyl methyltransferase 1 6221193-6235972 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA032024, HPA032025 Uncertain Liver cancer:1.79e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 45.1 Expressed in all +RPL22 EAP, L22 ENSG00000116251 Ribosomal protein L22 1 6181269-6209389 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA068294 Approved Nucleus
Nucleoli Expressed in all Expressed in all ovary: 1343.4 Expressed in all +CHD5 ENSG00000116254 Chromodomain helicase DNA binding protein 5 1 6101793-6180123 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015809, HPA055477 Supported Supported Nucleoplasm
Nuclear speckles
Cytosol Mixed Tissue enriched 7 cerebral cortex: 42.1 testis: 6.2 Cell line enhanced SCLC-21H: 16.0;U-2 OS: 6.3 +QSOX1 QSCN6 ENSG00000116260 Quiescin sulfhydryl oxidase 1 1 180154834-180204030 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA042127, HPA056243 Uncertain Supported Golgi apparatus
Vesicles Renal cancer:1.86e-5 (unfavourable) Expressed in all Expressed in all gallbladder: 233.0 Expressed in all +STXBP3 UNC-18C ENSG00000116266 Syntaxin binding protein 3 1 108746674-108809526 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027225 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 65.9 Expressed in all +PHF13 MGC43399 ENSG00000116273 PHD finger protein 13 1 6613685-6624033 Predicted intracellular proteins Evidence at protein level HPA026830 Uncertain Liver cancer:6.86e-4 (unfavourable) Expressed in all Expressed in all testis: 58.9 Expressed in all +ERRFI1 GENE-33, MIG-6, RALT ENSG00000116285 ERBB receptor feedback inhibitor 1 1 8004404-8026308 Predicted intracellular proteins Evidence at protein level HPA027206 Supported Cytosol Expressed in all Expressed in all liver: 369.4 Cell line enhanced HHSteC: 468.0;LHCN-M2: 368.0 +PARK7 DJ-1, DJ1 ENSG00000116288 Parkinsonism associated deglycase 1 7954291-7985505 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004190, CAB005870 Enhanced Supported Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland: 515.7 Expressed in all +KIAA1324 EIG121, maba1 ENSG00000116299 KIAA1324 1 109113679-109206781 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA029869, HPA070749 Enhanced Supported Plasma membrane Endometrial cancer:2.14e-7 (favourable), Lung cancer:5.69e-5 (favourable), Ovarian cancer:2.16e-4 (favourable) Mixed Mixed cervix, uterine: 129.0 Cell line enhanced MCF7: 21.5;SCLC-21H: 20.3;SK-BR-3: 15.8;T-47d: 68.2;U-87 MG: 13.3 +OPRD1 ENSG00000116329 Opioid receptor delta 1 1 28812142-28871267 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA070831 Approved Tissue enhanced Tissue enhanced cerebral cortex: 2.6 adrenal gland: 0.8 Group enriched 12 RH-30: 15.8;SCLC-21H: 7.6;SH-SY5Y: 6.9;WM-115: 21.7 +AMPD2 SPG63 ENSG00000116337 Adenosine monophosphate deaminase 2 1 109616104-109632051 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027137, HPA045760, HPA050590 Approved Approved Enhanced Cytosol Renal cancer:3.78e-10 (unfavourable) Expressed in all Expressed in all bone marrow: 82.4 Expressed in all +SRSF4 SFRS4, SRP75 ENSG00000116350 Serine and arginine rich splicing factor 4 1 29147743-29181987 Predicted intracellular proteins Evidence at protein level HPA050975 Supported Supported Nuclear speckles Melanoma:3.27e-4 (unfavourable), Prostate cancer:4.26e-4 (unfavourable), Renal cancer:4.30e-4 (unfavourable) Expressed in all Expressed in all placenta: 78.8 Expressed in all +MECR CGI-63, ETR1, FASN2B, NRBF1 ENSG00000116353 Mitochondrial trans-2-enoyl-CoA reductase 1 29192873-29230942 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA022018, HPA022030, HPA028740 Enhanced Supported Mitochondria Renal cancer:5.81e-6 (favourable), Urothelial cancer:5.29e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 18.4 Expressed in all +KCNC4 C1orf30, HKSHIIIC, Kv3.4 ENSG00000116396 Potassium voltage-gated channel subfamily C member 4 1 110211343-110283100 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA014740 Approved Nucleoli
Cytosol Mixed Mixed parathyroid gland: 13.6 Cell line enhanced HDLM-2: 17.2;U-87 MG: 15.3 +EDEM3 C1orf22 ENSG00000116406 ER degradation enhancing alpha-mannosidase like protein 3 1 184690231-184754913 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA025754, HPA025755, HPA027297 Approved Approved Endoplasmic reticulum Renal cancer:1.63e-6 (unfavourable) Expressed in all Expressed in all stomach: 34.4 Expressed in all +WDR77 MEP50, p44 ENSG00000116455 WD repeat domain 77 1 111439890-111449376 Predicted intracellular proteins Evidence at protein level HPA026437, HPA026448, HPA027271 Approved Supported Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:2.06e-6 (unfavourable), Ovarian cancer:7.88e-4 (favourable) Expressed in all Expressed in all fallopian tube: 162.6 Expressed in all +ATP5F1 ENSG00000116459 ATP synthase, H+ transporting, mitochondrial Fo complex subunit B1 1 111448864-111462773 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA046067, HPA057347 Enhanced Supported Mitochondria Renal cancer:3.26e-9 (favourable), Stomach cancer:8.07e-4 (favourable) Expressed in all Expressed in all heart muscle: 50.4 Expressed in all +RAP1A KREV-1, SMGP21 ENSG00000116473 RAP1A, member of RAS oncogene family 1 111542218-111716691 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Expressed in all Expressed in all parathyroid gland: 203.3 Expressed in all +HDAC1 GON-10, HD1, RPD3L1 ENSG00000116478 Histone deacetylase 1 1 32292086-32333635 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005017, HPA029693, CAB068191 Enhanced Enhanced Nucleoplasm Liver cancer:5.76e-7 (unfavourable), Renal cancer:1.04e-5 (unfavourable) Expressed in all Expressed in all lymph node: 139.0 Expressed in all +CAPZA1 ENSG00000116489 Capping actin protein of muscle Z-line alpha subunit 1 1 112619173-112671619 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB045963 Approved Renal cancer:0.00e+0 (unfavourable), Liver cancer:2.54e-6 (unfavourable) Expressed in all Expressed in all lymph node: 133.9 Expressed in all +S100PBP FLJ12903, S100PBPR ENSG00000116497 S100P binding protein 1 32816767-32858879 Predicted intracellular proteins Evidence at protein level HPA027242, HPA027328 Approved Supported Nuclear speckles Liver cancer:1.26e-6 (unfavourable), Head and neck cancer:5.22e-5 (favourable), Renal cancer:9.03e-4 (unfavourable) Expressed in all Expressed in all testis: 61.5 Expressed in all +RNF19B FLJ90005, IBRDC3 ENSG00000116514 Ring finger protein 19B 1 32936445-32964685 Predicted membrane proteins Evidence at protein level HPA049587 Approved Approved Cytosol Liver cancer:5.41e-6 (unfavourable), Renal cancer:4.39e-5 (favourable), Head and neck cancer:3.39e-4 (favourable) Expressed in all Expressed in all testis: 155.3 Expressed in all +SCAMP3 C1orf3 ENSG00000116521 Secretory carrier membrane protein 3 1 155255979-155262430 Predicted membrane proteins Evidence at protein level HPA071167 Supported Vesicles Liver cancer:2.92e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 46.9 Expressed in all +TRIM62 DEAR1, FLJ10759 ENSG00000116525 Tripartite motif containing 62 1 33145402-33182059 Enzymes, Predicted intracellular proteins Evidence at protein level HPA050061 Approved Vesicles
Focal adhesion sites Renal cancer:7.08e-5 (unfavourable) Expressed in all Mixed skin: 11.6 Expressed in all +ASH1L ASH1, ASH1L1, huASH1, KMT2H ENSG00000116539 ASH1 like histone lysine methyltransferase 1 155335268-155562807 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004806 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:3.80e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 37.9 Expressed in all +DLGAP3 DAP3, SAPAP3 ENSG00000116544 DLG associated protein 3 1 34865436-34929585 Predicted intracellular proteins Evidence at protein level HPA026445 Enhanced Group enriched Group enriched 12 cerebral cortex: 21.9;testis: 5.7 spleen: 1.1 Cell line enhanced Daudi: 5.7;NTERA-2: 4.2;SCLC-21H: 14.7 +SFPQ PPP1R140, PSF ENSG00000116560 Splicing factor proline and glutamine rich 1 35176378-35193148 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009886, HPA047513, HPA054689 Enhanced Enhanced Nucleoplasm Liver cancer:7.91e-13 (unfavourable), Breast cancer:9.56e-5 (favourable) Expressed in all Expressed in all bone marrow: 135.5 Expressed in all +RHOU ARHU, CDC42L1, DJ646B12.2, fJ646B12.2, FLJ10616, hG28K, WRCH-1, WRCH1 ENSG00000116574 Ras homolog family member U 1 228735077-228746669 Predicted intracellular proteins Evidence at protein level HPA049592 Approved Renal cancer:3.56e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 62.1 Cell line enhanced BEWO: 172.7;MOLT-4: 67.1;RT4: 62.2 +GON4L FLJ20203, GON-4, GON4, YARP ENSG00000116580 Gon-4 like 1 155749662-155859400 Predicted intracellular proteins Evidence at protein level HPA006986, HPA057305, HPA074504 Uncertain Enhanced Nucleoplasm
Nuclear bodies Endometrial cancer:4.19e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.8 Expressed in all +ARHGEF2 GEF-H1, KIAA0651, LFP40, P40 ENSG00000116584 Rho/Rac guanine nucleotide exchange factor 2 1 155946851-156007070 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043437 Approved Renal cancer:7.17e-6 (unfavourable), Liver cancer:9.20e-6 (unfavourable) Expressed in all Expressed in all lung: 95.0 Expressed in all +LAMTOR2 ENDAP, MAPBPIP, MAPKSP1AP, p14, Ragulator2, ROBLD3 ENSG00000116586 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 1 156054752-156058510 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA004126 Approved Approved Nucleoplasm
Vesicles Renal cancer:1.10e-6 (unfavourable) Expressed in all Expressed in all epididymis: 84.7 Expressed in all +MEF2D ENSG00000116604 Myocyte enhancer factor 2D 1 156463727-156500828 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004807, HPA007114 Enhanced Enhanced Nucleoplasm Renal cancer:7.53e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 55.5 Expressed in all +DOCK7 KIAA1771, ZIR2 ENSG00000116641 Dedicator of cytokinesis 7 1 62454298-62688368 Disease related genes, Predicted intracellular proteins Evidence at protein level Liver cancer:1.12e-4 (unfavourable) Expressed in all Expressed in all testis: 30.4 Mixed +SRM SPS1, SRML1 ENSG00000116649 Spermidine synthase 1 11054584-11060024 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015746 Approved Approved Nucleoplasm
Cytosol Renal cancer:3.80e-8 (unfavourable), Liver cancer:2.25e-5 (unfavourable) Expressed in all Expressed in all appendix: 73.5 Expressed in all +FBXO2 Fbg1, Fbs1, FBX2, Nfb42, OCP1 ENSG00000116661 F-box protein 2 1 11648367-11655785 Predicted intracellular proteins Evidence at protein level HPA005472 Approved Nucleoplasm
Cytosol Renal cancer:3.45e-6 (favourable) Expressed in all Tissue enhanced cerebral cortex: 80.5 adrenal gland: 27.7 Cell line enhanced CACO-2: 75.6;Hep G2: 131.1;SiHa: 376.0 +FBXO6 FBG2, FBS2, FBX6, Fbx6b ENSG00000116663 F-box protein 6 1 11664124-11674354 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA051175 Approved Renal cancer:7.83e-6 (unfavourable), Urothelial cancer:5.90e-4 (favourable), Ovarian cancer:7.12e-4 (favourable) Expressed in all Expressed in all fallopian tube: 21.4 Mixed +C1orf21 PIG13 ENSG00000116667 Chromosome 1 open reading frame 21 1 184387058-184629020 Predicted intracellular proteins Evidence at protein level HPA026831 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.35e-8 (unfavourable) Expressed in all Mixed skin: 30.1 Cell line enhanced HDLM-2: 32.8 +SWT1 C1orf26, FLJ20121, HsSwt1 ENSG00000116668 SWT1, RNA endoribonuclease homolog 1 185157080-185291765 Predicted intracellular proteins Evidence at protein level HPA024214, HPA027334 Enhanced Approved Cytosol Renal cancer:5.63e-4 (favourable) Expressed in all Tissue enriched 8 testis: 69.4 thyroid gland: 8.7 Mixed +MAD2L2 MAD2B, POLZ2, REV7 ENSG00000116670 MAD2 mitotic arrest deficient-like 2 (yeast) 1 11674480-11691650 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB008110, HPA024176 Approved Supported Nucleoli
Cytosol Expressed in all Expressed in all testis: 73.6 Expressed in all +DNAJC6 KIAA0473, PARK19 ENSG00000116675 DnaJ heat shock protein family (Hsp40) member C6 1 65248219-65415869 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA031182, HPA054917 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:2.81e-4 (favourable) Tissue enhanced Tissue enriched 10 cerebral cortex: 162.8 adrenal gland: 15.6 Cell line enhanced HDLM-2: 58.7;HEL: 150.3;K-562: 59.3 +LEPR CD295, OBR ENSG00000116678 Leptin receptor 1 65420652-65641559 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA030899 Approved Approved Vesicles Tissue enriched Mixed liver: 67.9 Cell line enhanced K-562: 102.4;RPTEC TERT1: 39.6 +IVNS1ABP HSPC068, KIAA0850, KLHL39, ND1, NS-1, NS1-BP ENSG00000116679 Influenza virus NS1A binding protein 1 185296388-185317329 Predicted intracellular proteins Evidence at protein level HPA003405 Approved Supported Cytosol Expressed in all Expressed in all bone marrow: 299.5 Expressed in all +KIAA2013 MGC33867, RP5-1077B9.1 ENSG00000116685 KIAA2013 1 11919591-11926428 Predicted membrane proteins Evidence at protein level HPA052677, HPA060536 Uncertain Approved Golgi apparatus
Cytosol Expressed in all Expressed in all small intestine: 68.1 Expressed in all +MFN2 CMT2A2, CPRP1, KIAA0214, MARF ENSG00000116688 Mitofusin 2 1 11980181-12013514 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA030554 Uncertain Renal cancer:2.36e-8 (favourable) Expressed in all Expressed in all heart muscle: 200.3 Expressed in all +PRG4 bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP ENSG00000116690 Proteoglycan 4 1 186296279-186314562 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA028523 Uncertain Tissue enriched Tissue enriched 6 liver: 97.4 lung: 15.4 Cell line enhanced ASC diff: 195.2;hTEC/SVTERT24-B: 44.2;SiHa: 34.4 +MIIP FLJ12438, IIp45 ENSG00000116691 Migration and invasion inhibitory protein 1 12019466-12032045 Predicted intracellular proteins Evidence at protein level HPA044948 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:8.26e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 27.4 Cell line enriched 8 HDLM-2: 334.7 +SMG7 C1orf16, EST1C, KIAA0250, SGA56M, SMG-7 ENSG00000116698 SMG7, nonsense mediated mRNA decay factor 1 183472216-183598246 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029350 Supported Supported Intermediate filaments
Cytosol Expressed in all Expressed in all testis: 123.1 Expressed in all +NCF2 NOXA2, p67phox ENSG00000116701 Neutrophil cytosolic factor 2 1 183555563-183590876 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002327, HPA006040, CAB022160 Enhanced Enhanced Nucleoli
Cytosol Liver cancer:7.91e-6 (unfavourable) Expressed in all Tissue enhanced bone marrow: 127.5 lung: 111.6 Cell line enhanced A-431: 22.9;hTERT-HME1: 39.8;U-2 OS: 52.5 +PDC MEKA ENSG00000116703 Phosducin 1 186443566-186461122 Predicted intracellular proteins Evidence at protein level HPA062235 Supported Not detected Not detected cerebral cortex,testis: 0.3 Not detected +SLC35D1 KIAA0260, UGTREL7 ENSG00000116704 Solute carrier family 35 member D1 1 66999332-67054099 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Lung cancer:6.55e-4 (unfavourable), Endometrial cancer:7.47e-4 (unfavourable) Expressed in all Expressed in all liver: 38.5 Expressed in all +PLA2G4A cPLA2-alpha, PLA2G4 ENSG00000116711 Phospholipase A2 group IVA 1 186828953-186988981 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010050, HPA050062, HPA054206 Approved Supported Cytosol Endometrial cancer:2.85e-4 (favourable), Breast cancer:9.07e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 200.5 seminal vesicle: 68.3 Cell line enhanced RPMI-8226: 50.7;U-2197: 61.7 +GADD45A DDIT1, GADD45 ENSG00000116717 Growth arrest and DNA damage inducible alpha 1 67685061-67688338 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA053420 Supported Nuclear speckles Renal cancer:8.06e-6 (favourable) Expressed in all Expressed in all thyroid gland: 91.1 Expressed in all +PRAMEF1 ENSG00000116721 PRAME family member 1 1 12791397-12796628 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.1 Not detected +PRAMEF12 ENSG00000116726 PRAME family member 12 1 12774841-12777906 Plasma proteins, Predicted intracellular proteins No evidence HPA045286, HPA051704 Uncertain Uncertain Nucleoplasm Not detected Not detected all non-specific tissues: 0.0 Not detected +WLS C1orf139, EVI, FLJ23091, GPR177, mig-14, MRP, wls ENSG00000116729 Wntless Wnt ligand secretion mediator 1 68098473-68233120 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA069520 Approved Renal cancer:3.67e-7 (favourable), Urothelial cancer:3.51e-4 (unfavourable), Breast cancer:4.03e-4 (favourable), Ovarian cancer:9.43e-4 (favourable) Expressed in all Expressed in all epididymis: 163.8 Cell line enhanced AF22: 388.0 +PRDM2 HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2 ENSG00000116731 PR/SET domain 2 1 13700198-13825079 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005809 Approved Approved Nucleus
Golgi apparatus Expressed in all Expressed in all bone marrow: 51.2 Expressed in all +RGS2 G0S8 ENSG00000116741 Regulator of G-protein signaling 2 1 192809039-192812283 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013385 Approved Cytosol Renal cancer:2.90e-5 (unfavourable), Breast cancer:2.43e-4 (favourable), Stomach cancer:3.56e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 749.0 Cell line enhanced hTCEpi: 101.7;PC-3: 208.8 +RPE65 BCO3, LCA2, rd12, RP20 ENSG00000116745 RPE65, retinoid isomerohydrolase 1 68428822-68449959 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Group enriched Tissue enhanced cerebral cortex: 2.7;prostate: 3.0;seminal vesicle: 6.2 endometrium: 1.0 Group enriched 27 A-431: 3.0;PC-3: 5.3;U-2 OS: 1.4 +TROVE2 Ro60, SSA2 ENSG00000116747 TROVE domain family member 2 1 193059422-193091777 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002835, HPA005142 Uncertain Approved Nucleoplasm
Cytosol Thyroid cancer:3.31e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 28.1 Expressed in all +AMPD1 MAD, MADA ENSG00000116748 Adenosine monophosphate deaminase 1 1 114673090-114695618 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA026478, HPA028080 Enhanced Mixed Tissue enriched 12 skeletal muscle: 193.6 duodenum: 16.5 Cell line enriched 32 U-266/70: 6.6 +UCHL5 CGI-70, INO80R, UCH37 ENSG00000116750 Ubiquitin C-terminal hydrolase L5 1 193012250-193060080 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005908, HPA006069, HPA075383 Approved Approved Approved Nucleoplasm
Mitochondria Thyroid cancer:7.10e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 43.0 Expressed in all +BCAS2 DAM1, Snt309, SPF27 ENSG00000116752 BCAS2, pre-mRNA processing factor 1 114567557-114581639 Predicted intracellular proteins Evidence at protein level HPA067881 Enhanced Supported Nuclear speckles
Centrosome Liver cancer:8.23e-7 (unfavourable), Prostate cancer:4.27e-4 (unfavourable), Thyroid cancer:5.24e-4 (unfavourable), Renal cancer:6.49e-4 (favourable), Ovarian cancer:7.96e-4 (favourable) Expressed in all Expressed in all thyroid gland: 71.1 Expressed in all +SRSF11 NET2, p54, SFRS11 ENSG00000116754 Serine and arginine rich splicing factor 11 1 70205682-70253052 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008762 Supported Supported Nuclear speckles Renal cancer:6.53e-6 (unfavourable), Liver cancer:3.91e-4 (unfavourable) Expressed in all Expressed in all endometrium: 96.1 Expressed in all +CTH ENSG00000116761 Cystathionine gamma-lyase 1 70411218-70439851 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021591, HPA023300 Enhanced Liver cancer:8.69e-4 (favourable) Group enriched Expressed in all liver: 73.2 Cell line enhanced Karpas-707: 52.3;SK-MEL-30: 75.8 +AGMAT FLJ23384 ENSG00000116771 Agmatinase 1 15572353-15585110 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026443, HPA028321 Enhanced Renal cancer:5.13e-4 (favourable) Group enriched Tissue enhanced kidney: 158.9 liver: 36.6 Cell line enhanced CACO-2: 35.2;Hep G2: 70.8 +OLFML3 HNOEL-iso, OLF44 ENSG00000116774 Olfactomedin like 3 1 113979391-114035572 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027991 Supported Vesicles Renal cancer:3.45e-5 (unfavourable) Expressed in all Mixed cervix, uterine: 266.9 Cell line enhanced ASC diff: 395.8;BJ hTERT+: 302.6;HSkMC: 419.4;LHCN-M2: 496.4 +TNNI3K CARK ENSG00000116783 TNNI3 interacting kinase 1 74235401-74544428 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 7 heart muscle: 39.5 testis: 5.3 Not detected +CFHR3 CFHL3, DOWN16, FHR-3, FHR3, HLF4 ENSG00000116785 Complement factor H related 3 1 196774795-196795406 Plasma proteins, Predicted secreted proteins Evidence at protein level Liver cancer:2.86e-5 (favourable) Tissue enriched Tissue enriched 244 liver: 314.2 adipose tissue: 1.2 Cell line enhanced NTERA-2: 2.1;T-47d: 4.2;U-266/70: 6.1 +PLEKHM2 KIAA0842 ENSG00000116786 Pleckstrin homology and RUN domain containing M2 1 15684332-15734769 Predicted intracellular proteins Evidence at protein level HPA032304 Approved Liver cancer:1.36e-8 (unfavourable) Expressed in all Expressed in all cerebral cortex: 50.0 Expressed in all +CRYZ ENSG00000116791 Crystallin zeta 1 74705482-74733408 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021921, HPA023290 Approved Supported Cytosol Expressed in all Expressed in all kidney: 345.5 Expressed in all +PHTF1 PHTF ENSG00000116793 Putative homeodomain transcription factor 1 1 113696831-113759489 Plasma proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA059486 Approved Nucleoli
Nuclear bodies Renal cancer:1.21e-6 (unfavourable) Expressed in all Tissue enhanced testis: 54.4 parathyroid gland: 19.0 Mixed +ZBTB17 MIZ1, pHZ-67, ZNF151, ZNF60 ENSG00000116809 Zinc finger and BTB domain containing 17 1 15941869-15976132 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005789 Approved Liver cancer:2.38e-6 (unfavourable), Renal cancer:3.27e-5 (unfavourable), Urothelial cancer:2.04e-4 (favourable) Expressed in all Expressed in all testis: 21.9 Expressed in all +CD58 LFA3 ENSG00000116815 CD58 molecule 1 116514535-116571039 CD markers, Predicted membrane proteins Evidence at protein level Liver cancer:2.32e-6 (unfavourable), Pancreatic cancer:5.60e-4 (unfavourable) Expressed in all Expressed in all lung: 42.7 Expressed in all +TFAP2E AP2E ENSG00000116819 Transcription factor AP-2 epsilon 1 35573370-35595328 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Tissue enhanced skin: 7.2 lymph node: 2.1 Cell line enhanced NB-4: 4.5;U-937: 4.6 +CD2 SRBC ENSG00000116824 CD2 molecule 1 116754385-116769228 CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002430, HPA003883 Enhanced Renal cancer:4.82e-6 (unfavourable), Endometrial cancer:1.69e-5 (favourable), Melanoma:3.97e-5 (favourable), Head and neck cancer:7.46e-5 (favourable), Cervical cancer:1.47e-4 (favourable), Breast cancer:4.36e-4 (favourable), Ovarian cancer:7.72e-4 (favourable) Expressed in all Tissue enhanced lymph node: 131.1 tonsil: 70.8 Group enriched 27 HDLM-2: 201.2;MOLT-4: 129.2 +TTF2 HuF2, ZGRF6 ENSG00000116830 Transcription termination factor 2 1 117060303-117107453 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005776, HPA070762 Approved Supported Cytosol Expressed in all Mixed lymph node: 8.7 Expressed in all +NR5A2 B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1 ENSG00000116833 Nuclear receptor subfamily 5 group A member 2 1 200027602-200177424 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005455, HPA017067 Supported Uncertain Nuclear speckles Tissue enhanced Mixed liver: 19.5 Cell line enhanced A549: 22.3;HAP1: 15.3;HUVEC TERT2: 17.0 +KIF21B DKFZP434J212, KIAA0449 ENSG00000116852 Kinesin family member 21B 1 200969390-201023700 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027249, HPA027274 Approved Mixed Tissue enhanced cerebral cortex: 28.8 bone marrow: 22.9 Cell line enhanced HMC-1: 37.2;Karpas-707: 36.3;U-266/70: 69.6;U-266/84: 31.7 +TMEM9 TMEM9A ENSG00000116857 Transmembrane protein 9 1 201134772-201171574 Predicted membrane proteins Evidence at protein level Head and neck cancer:3.93e-4 (unfavourable), Cervical cancer:6.57e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 122.7 Expressed in all +ADPRHL2 ARH3, FLJ20446 ENSG00000116863 ADP-ribosylhydrolase like 2 1 36088875-36093932 Enzymes, Predicted secreted proteins Evidence at protein level HPA027104, HPA027141 Approved Enhanced Nucleoplasm Liver cancer:2.10e-7 (unfavourable), Renal cancer:3.71e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 41.1 Expressed in all +MAP7D1 FLJ10350, FLJ39022, PARCC1, RPRC1 ENSG00000116871 MAP7 domain containing 1 1 36155579-36180849 Predicted intracellular proteins Evidence at protein level HPA028075 Approved Approved Microtubules
Cytosol Liver cancer:1.49e-6 (unfavourable), Renal cancer:8.56e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 116.6 Expressed in all +WARS2 TrpRS ENSG00000116874 Tryptophanyl tRNA synthetase 2, mitochondrial 1 119031216-119140671 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069692 Enhanced Supported Plasma membrane
Mitochondria Renal cancer:1.45e-4 (favourable) Expressed in all Expressed in all fallopian tube: 15.2 Expressed in all +HAO2 GIG16, HAOX2 ENSG00000116882 Hydroxyacid oxidase 2 1 119368779-119394130 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.92e-4 (favourable) Group enriched Group enriched 300 kidney: 317.5;liver: 219.8 adrenal gland,breast: 0.8 Not detected +OSCP1 C1orf102, NOR1 ENSG00000116885 Organic solute carrier partner 1 1 36415827-36450451 Predicted intracellular proteins, Transporters Evidence at protein level HPA028436, HPA052655 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Renal cancer:2.18e-6 (favourable), Endometrial cancer:6.88e-4 (favourable) Expressed in all Expressed in all testis: 126.7 Mixed +MRPS15 FLJ11564 ENSG00000116898 Mitochondrial ribosomal protein S15 1 36455718-36464437 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA028100, HPA028134, HPA067137 Enhanced Supported Mitochondria Renal cancer:3.55e-4 (unfavourable), Liver cancer:3.59e-4 (unfavourable), Ovarian cancer:7.83e-4 (favourable) Expressed in all Expressed in all testis: 242.5 Expressed in all +EXOC8 EXO84, Exo84p, SEC84 ENSG00000116903 Exocyst complex component 8 1 231332753-231337852 Predicted intracellular proteins, Transporters Evidence at protein level HPA027438 Approved Supported Cytosol Expressed in all Expressed in all parathyroid gland: 17.4 Expressed in all +GNPAT DAP-AT, DAPAT, DHAPAT ENSG00000116906 Glyceronephosphate O-acyltransferase 1 231241207-231277973 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Renal cancer:8.29e-6 (unfavourable) Expressed in all Expressed in all testis: 59.7 Expressed in all +TSNAX TRAX ENSG00000116918 Translin associated factor X 1 231528653-231566524 Predicted intracellular proteins Evidence at protein level HPA031054, HPA031055, CAB034263 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 54.4 Expressed in all +C1orf109 FLJ20508 ENSG00000116922 Chromosome 1 open reading frame 109 1 37681570-37692249 Predicted intracellular proteins Evidence at protein level HPA027110, HPA027127 Supported Approved Nucleus
Cytosol Liver cancer:1.76e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.2 Expressed in all +RRAGC FLJ13311, GTR2 ENSG00000116954 Ras related GTP binding C 1 38838198-38859823 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018247, HPA055489 Enhanced Supported Nucleus
Vesicles Liver cancer:9.97e-9 (unfavourable) Expressed in all Expressed in all adipose tissue: 40.4 Expressed in all +TBCE HRD, KCS, KCS1, pac2 ENSG00000116957 Tubulin folding cofactor E 1 235367360-235448968 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026552, HPA026557 Uncertain Renal cancer:7.87e-13 (unfavourable), Head and neck cancer:7.90e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 18.3 Expressed in all +NID1 entactin, NID ENSG00000116962 Nidogen 1 1 235975830-236065162 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB010044 Approved Renal cancer:5.38e-8 (unfavourable) Expressed in all Expressed in all placenta: 326.5 Cell line enhanced ASC diff: 1062.5;ASC TERT1: 502.4;HSkMC: 444.4 +LGALS8 PCTA-1 ENSG00000116977 Galectin 8 1 236518000-236552981 Predicted intracellular proteins Evidence at protein level HPA012734, HPA030491 Approved Approved Plasma membrane Renal cancer:4.93e-7 (unfavourable), Lung cancer:9.40e-4 (favourable) Expressed in all Expressed in all testis: 101.6 Mixed +NT5C1A CN-I, CN-IA, CN1, CN1A, MGC119199, MGC119201 ENSG00000116981 5'-nucleotidase, cytosolic IA 1 39659121-39672038 Enzymes, Predicted intracellular proteins Evidence at protein level HPA050283, HPA054158 Supported Not detected Tissue enhanced heart muscle: 7.5;skeletal muscle: 24.9 cerebral cortex: 4.8 Cell line enriched 20 SH-SY5Y: 18.9 +HPCAL4 DKFZp761G122, HLP4 ENSG00000116983 Hippocalcin like 4 1 39678648-39691689 Predicted intracellular proteins Evidence at protein level HPA053808 Approved Cytosol Group enriched Tissue enriched 11 cerebral cortex: 145.7 adrenal gland: 13.3 Cell line enhanced SH-SY5Y: 9.4;SK-MEL-30: 2.2;U-266/84: 2.1 +MTR cblG ENSG00000116984 5-methyltetrahydrofolate-homocysteine methyltransferase 1 236795281-236903981 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA044474, HPA054915 Approved Supported Cytosol Thyroid cancer:5.75e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.7 Expressed in all +BMP8B BMP8, OP-2 ENSG00000116985 Bone morphogenetic protein 8b 1 39757182-39788861 Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced thyroid gland: 33.5 adrenal gland: 7.5 Cell line enhanced THP-1: 80.8;U-266/84: 37.5;WM-115: 56.0 +MYCL bHLHe38, LMYC, MYCL1 ENSG00000116990 V-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 1 39895426-39902256 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063132 Supported Nucleus Lung cancer:4.49e-4 (favourable) Expressed in all Tissue enhanced skin: 41.6 urinary bladder: 23.7 Group enriched 7 U-266/70: 372.1;U-266/84: 268.8 +SIPA1L2 KIAA1389 ENSG00000116991 Signal induced proliferation associated 1 like 2 1 232397965-232561558 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024181, HPA027224 Approved Approved Nuclear membrane
Nuclear bodies
Golgi apparatus Renal cancer:8.15e-4 (unfavourable) Expressed in all Mixed placenta: 29.1 Cell line enhanced AF22: 74.1;NTERA-2: 60.3;WM-115: 50.8 +ZP4 ZPB ENSG00000116996 Zona pellucida glycoprotein 4 1 237877864-237890922 Predicted membrane proteins Evidence at protein level HPA008547 Supported Not detected Not detected tonsil: 0.2 Cell line enhanced BJ hTERT+: 2.6 +RLF Zn-15L, ZNF292L ENSG00000117000 Rearranged L-myc fusion 1 40161373-40240921 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054653, HPA057300 Uncertain Approved Nucleus Renal cancer:7.68e-6 (unfavourable), Liver cancer:1.75e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 20.8 Expressed in all +KMO ENSG00000117009 Kynurenine 3-monooxygenase 1 241532134-241595642 Enzymes, Predicted membrane proteins Evidence at protein level HPA031115, HPA056942 Enhanced Renal cancer:6.49e-8 (unfavourable) Mixed Tissue enhanced kidney: 32.3;liver: 47.7 spleen: 10.8 Cell line enhanced RPMI-8226: 6.1;RPTEC TERT1: 16.3;SK-BR-3: 8.4;U-698: 6.4 +ZNF684 MGC27466 ENSG00000117010 Zinc finger protein 684 1 40531561-40548169 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA059153 Uncertain Approved Nucleus
Cytosol Renal cancer:4.89e-10 (favourable) Expressed in all Mixed kidney: 6.8 Cell line enhanced THP-1: 23.3 +KCNQ4 DFNA2, Kv7.4 ENSG00000117013 Potassium voltage-gated channel subfamily Q member 4 1 40784012-40840452 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA018305 Uncertain Mixed Mixed smooth muscle: 2.5 Cell line enhanced HAP1: 1.9;HEK 293: 2.5;K-562: 2.6 +RIMS3 NIM3, RIM3 ENSG00000117016 Regulating synaptic membrane exocytosis 3 1 40620679-40665657 Predicted intracellular proteins Evidence at protein level HPA055285 Approved Nucleoli
Mitochondria Mixed Tissue enriched 7 cerebral cortex: 60.4 adrenal gland: 8.3 Cell line enhanced Daudi: 55.3;SCLC-21H: 23.5;SH-SY5Y: 37.4;U-87 MG: 31.5 +AKT3 PKBG, PRKBG, RAC-gamma ENSG00000117020 AKT serine/threonine kinase 3 1 243488233-243851079 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB013090, HPA026441 Approved Supported Cytosol Urothelial cancer:9.27e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 51.6 Mixed +ETV3 PE-1 ENSG00000117036 ETS variant 3 1 157121191-157138474 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004794 Supported Approved Nucleus Expressed in all Expressed in all parathyroid gland: 45.4 Expressed in all +ACADM ACAD1, MCAD, MCADH ENSG00000117054 Acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1 75724347-75787575 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006198, HPA026542 Enhanced Enhanced Mitochondria Renal cancer:3.83e-8 (favourable), Colorectal cancer:7.30e-4 (favourable) Expressed in all Expressed in all kidney: 328.0 Expressed in all +ST6GALNAC5 MGC3184, SIAT7E, ST6GalNAcV ENSG00000117069 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 1 76867441-77065711 Predicted secreted proteins Evidence at protein level HPA065593, HPA070354 Uncertain Approved Vesicles Tissue enhanced Mixed lung: 8.8 Cell line enhanced AF22: 7.6;fHDF/TERT166: 7.3;SH-SY5Y: 7.0;U-2 OS: 7.8 +SLAMF1 CD150, SLAM ENSG00000117090 Signaling lymphocytic activation molecule family member 1 1 160608100-160647295 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002438, HPA069319 Enhanced Mixed Tissue enhanced appendix: 15.4;lymph node: 21.1;tonsil: 14.3 spleen: 7.9 Cell line enriched 134 HDLM-2: 142.1 +CD48 BCM1, BLAST, hCD48, mCD48, SLAMF2 ENSG00000117091 CD48 molecule 1 160678746-160711851 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002497, HPA055146 Enhanced Supported Nucleoli fibrillar center
Plasma membrane
Cytosol Renal cancer:3.36e-4 (unfavourable), Breast cancer:3.91e-4 (favourable), Colorectal cancer:4.17e-4 (favourable) Expressed in all Tissue enhanced lymph node: 311.4;spleen: 213.1;tonsil: 226.0 appendix: 148.5 Cell line enhanced Daudi: 153.4;HMC-1: 202.6;U-266/70: 372.1;U-266/84: 244.7 +ADGRL2 KIAA0786, LEC1, LPHH1, LPHN2 ENSG00000117114 Adhesion G protein-coupled receptor L2 1 81306160-81992436 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA043447 Approved Plasma membrane
Cell Junctions Endometrial cancer:1.33e-4 (unfavourable), Stomach cancer:3.00e-4 (unfavourable), Liver cancer:9.92e-4 (unfavourable) Expressed in all Mixed thyroid gland: 73.2 Cell line enhanced AF22: 246.2;hTEC/SVTERT24-B: 124.0;SH-SY5Y: 176.4 +PADI2 KIAA0994, PDI2 ENSG00000117115 Peptidyl arginine deiminase 2 1 17066761-17119435 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047735 Enhanced Mixed Tissue enhanced cerebral cortex: 85.0;colon: 89.8;rectum: 99.9;skeletal muscle: 108.6 breast: 48.8 Group enriched 5 A549: 10.4;RPTEC TERT1: 25.1;SK-BR-3: 38.1;T-47d: 13.1 +SDHB SDH, SDH1 ENSG00000117118 Succinate dehydrogenase complex iron sulfur subunit B 1 17018722-17054170 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002868, CAB009822, CAB068233, CAB068234, CAB068235 Enhanced Supported Nucleoplasm
Plasma membrane
Mitochondria Renal cancer:2.93e-7 (favourable) Expressed in all Expressed in all kidney: 215.2 Expressed in all +MFAP2 MAGP, MAGP-1 ENSG00000117122 Microfibrillar associated protein 2 1 16974502-16980835 Predicted secreted proteins Evidence at protein level HPA007354 Enhanced Renal cancer:2.52e-8 (unfavourable) Expressed in all Tissue enhanced gallbladder: 100.7 endometrium: 82.4 Cell line enhanced HUVEC TERT2: 193.6;SH-SY5Y: 203.2 +RPF1 BXDC5 ENSG00000117133 Ribosome production factor 1 homolog 1 84479259-84497790 Predicted intracellular proteins Evidence at protein level HPA024642 Supported Enhanced Nucleoli Liver cancer:1.60e-5 (unfavourable) Expressed in all Expressed in all testis: 58.7 Expressed in all +KDM5B CT31, JARID1B, PLU-1, PPP1R98, RBBP2H1A ENSG00000117139 Lysine demethylase 5B 1 202724491-202809470 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027179, HPA053723, CAB068193 Enhanced Supported Nucleus Expressed in all Tissue enriched 7 testis: 228.1 skin: 30.6 Mixed +UAP1 AgX, AGX1, SPAG2 ENSG00000117143 UDP-N-acetylglucosamine pyrophosphorylase 1 1 162561506-162599842 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA014659 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:5.12e-5 (unfavourable) Expressed in all Expressed in all testis: 166.1 Expressed in all +ACTL8 CT57 ENSG00000117148 Actin like 8 1 17755313-17827063 Predicted intracellular proteins Evidence at protein level HPA027176 Approved Cytosol Endometrial cancer:1.62e-6 (unfavourable), Head and neck cancer:7.02e-4 (unfavourable) Mixed Tissue enriched 35 testis: 10.0 colon,rectum: 0.2 Cell line enriched 9 U-266/84: 168.8 +CTBS CTB ENSG00000117151 Chitobiase 1 84549606-84574480 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB017043, HPA023594, HPA048810 Approved Uncertain Cytosol Expressed in all Mixed epididymis: 3.8 Mixed +RGS4 SCZD9 ENSG00000117152 Regulator of G-protein signaling 4 1 163068775-163076802 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030802 Approved Intermediate filaments Stomach cancer:1.92e-4 (unfavourable), Renal cancer:3.97e-4 (unfavourable), Glioma:4.33e-4 (unfavourable) Expressed in all Tissue enriched 5 cerebral cortex: 289.2 adrenal gland: 54.0 Cell line enhanced LHCN-M2: 245.4;SH-SY5Y: 612.2;TIME: 986.1 +KLHL12 C3IP1 ENSG00000117153 Kelch like family member 12 1 202891100-202928636 Predicted intracellular proteins Evidence at protein level HPA071324 Supported Vesicles
Microtubule organizing center Expressed in all Expressed in all testis: 81.9 Expressed in all +IGSF21 MGC15730, RP11-121A23.1 ENSG00000117154 Immunoglobin superfamily member 21 1 18107746-18378483 Predicted secreted proteins Evidence at protein level HPA044535 Approved Group enriched Tissue enhanced cerebral cortex: 28.9;spleen: 13.2 adrenal gland: 5.9 Cell line enriched 6 SCLC-21H: 21.2 +SSX2IP hMsd1 ENSG00000117155 SSX family member 2 interacting protein 1 84643707-84690803 Predicted intracellular proteins Evidence at protein level HPA027306, HPA075946 Approved Approved Cell Junctions Colorectal cancer:1.45e-4 (favourable) Expressed in all Tissue enhanced testis: 191.9 cerebral cortex: 45.8 Expressed in all +ZNHIT6 BCD1, C1orf181, FLJ20729, NY-BR-75 ENSG00000117174 Zinc finger HIT-type containing 6 1 85649423-85708433 Predicted intracellular proteins Evidence at protein level HPA018132 Uncertain Approved Nuclear speckles
Vesicles Liver cancer:6.08e-6 (unfavourable) Expressed in all Expressed in all cervix, uterine,endometrium: 21.1 Expressed in all +PLA2G2D sPLA2S ENSG00000117215 Phospholipase A2 group IID 1 20111939-20119566 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Cervical cancer:8.15e-5 (favourable), Breast cancer:4.35e-4 (favourable), Endometrial cancer:9.74e-4 (favourable) Tissue enriched Tissue enhanced lymph node: 118.5;tonsil: 54.0 appendix: 20.5 Cell line enriched 6 RPMI-8226: 5.9 +RBBP5 RBQ3, SWD1 ENSG00000117222 RB binding protein 5, histone lysine methyltransferase complex subunit 1 205086142-205122015 Predicted intracellular proteins Evidence at protein level HPA049042, HPA058085 Uncertain Enhanced Nucleus
Nucleoli Expressed in all Expressed in all thyroid gland: 16.4 Expressed in all +GBP3 FLJ10961 ENSG00000117226 Guanylate binding protein 3 1 89006666-89022894 Predicted intracellular proteins Evidence at protein level HPA045657 Approved Expressed in all Mixed duodenum: 77.0 Cell line enhanced BJ hTERT+: 64.5;LHCN-M2: 58.7 +GBP1 ENSG00000117228 Guanylate binding protein 1 1 89052319-89065360 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015450 Approved Renal cancer:5.12e-9 (unfavourable), Ovarian cancer:5.04e-4 (favourable), Colorectal cancer:8.32e-4 (favourable) Expressed in all Expressed in all appendix: 118.8 Cell line enhanced BJ hTERT+ SV40 Large T+: 109.8;BJ hTERT+ SV40 Large T+ RasG12V: 155.2 +KIF17 KIAA1405, KIF17B, KIF3X, KLP-2, OSM-3 ENSG00000117245 Kinesin family member 17 1 20664014-20718017 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA032085 Enhanced Approved Nucleoplasm
Plasma membrane Mixed Tissue enriched 6 testis: 23.7 cerebral cortex: 3.8 Cell line enhanced hTERT-HME1: 3.0;U-2 OS: 2.4 +GPR89A UNQ192 ENSG00000117262 G protein-coupled receptor 89A 1 145607990-145670648 Predicted membrane proteins Evidence at protein level HPA076096 Approved Endoplasmic reticulum Mixed Mixed kidney: 21.0 Expressed in all +CDK18 PCTAIRE3, PCTK3 ENSG00000117266 Cyclin dependent kinase 18 1 205504595-205532793 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045429 Approved Approved Actin filaments Renal cancer:5.07e-6 (unfavourable), Urothelial cancer:2.81e-5 (favourable) Expressed in all Mixed heart muscle: 62.0 Cell line enhanced HBEC3-KT: 25.4 +RAB29 RAB7L, RAB7L1 ENSG00000117280 RAB29, member RAS oncogene family 1 205767986-205775460 Predicted intracellular proteins Evidence at protein level CAB020822, HPA026303 Approved Approved Nuclear membrane
Nucleoli Endometrial cancer:1.82e-5 (unfavourable), Liver cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all kidney: 76.2 Expressed in all +CD160 BY55, NK1, NK28 ENSG00000117281 CD160 molecule 1 145719471-145739288 CD markers, Predicted secreted proteins Evidence at protein level Not detected Tissue enhanced spleen: 19.6 small intestine: 5.1 Mixed +ECE1 ECE ENSG00000117298 Endothelin converting enzyme 1 1 21217247-21345504 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001490, HPA013616 Approved Expressed in all Expressed in all parathyroid gland: 436.1 Expressed in all +HMGCL HL ENSG00000117305 3-hydroxymethyl-3-methylglutaryl-CoA lyase 1 23801885-23838620 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004727 Enhanced Renal cancer:5.07e-8 (favourable), Colorectal cancer:7.67e-4 (favourable) Expressed in all Expressed in all liver: 154.3 Expressed in all +GALE SDR1E1 ENSG00000117308 UDP-galactose-4-epimerase 1 23795599-23800804 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007340 Approved Approved Nucleus
Plasma membrane
Cytosol Thyroid cancer:2.68e-4 (favourable) Expressed in all Expressed in all stomach: 112.8 Expressed in all +ID3 bHLHb25, HEIR-1 ENSG00000117318 Inhibitor of DNA binding 3, HLH protein 1 23557918-23559794 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB021353, HPA024677 Approved Supported Nucleoplasm Endometrial cancer:1.27e-5 (favourable) Expressed in all Mixed seminal vesicle: 91.4 Cell line enhanced U-698: 261.7 +CR2 C3DR, CD21 ENSG00000117322 Complement C3d receptor 2 1 207454230-207489895 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002659, HPA052942, HPA060715 Enhanced Breast cancer:6.90e-4 (favourable) Mixed Group enriched 21 appendix: 68.3;lymph node: 206.0;spleen: 100.2;tonsil: 153.8 kidney: 6.2 Cell line enhanced Daudi: 17.1;MOLT-4: 10.7;RPMI-8226: 3.2 +CD46 MCP, MGC26544, MIC10, TLX, TRA2.10 ENSG00000117335 CD46 molecule 1 207752057-207795513 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB010401, HPA016903 Enhanced Approved Plasma membrane Cervical cancer:8.54e-5 (unfavourable), Stomach cancer:2.38e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 489.1 Expressed in all +PRPF3 hPrp3, Prp3, RP18, SNRNP90 ENSG00000117360 Pre-mRNA processing factor 3 1 150321476-150353195 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027226, HPA067116 Approved Enhanced Nucleoplasm Renal cancer:3.19e-5 (unfavourable), Liver cancer:6.59e-5 (unfavourable) Expressed in all Expressed in all endometrium: 40.6 Expressed in all +APH1A APH-1A, CGI-78 ENSG00000117362 Aph-1 homolog A, gamma-secretase subunit 1 150265399-150269580 Predicted membrane proteins Evidence at protein level CAB037272 Approved Expressed in all Expressed in all thyroid gland: 161.2 Expressed in all +P3H1 GROS1, LEPRE1, LEPRECAN, MGC117314 ENSG00000117385 Prolyl 3-hydroxylase 1 1 42746335-42767084 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA012113, HPA016980 Approved Approved Nucleoli
Vesicles Renal cancer:0.00e+0 (unfavourable), Liver cancer:4.95e-7 (unfavourable) Expressed in all Tissue enhanced placenta: 53.5 smooth muscle: 28.8 Expressed in all +SLC2A1 CSE, DYT18, DYT9, GLUT, GLUT1, HTLVR ENSG00000117394 Solute carrier family 2 member 1 1 42925375-42959173 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB002759, HPA031345, HPA058494 Enhanced Supported Enhanced Plasma membrane Renal cancer:4.55e-9 (unfavourable), Liver cancer:3.65e-8 (unfavourable), Pancreatic cancer:4.39e-5 (unfavourable), Lung cancer:1.09e-4 (unfavourable), Urothelial cancer:4.05e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 293.0 skin: 59.3 Expressed in all +EBNA1BP2 EBP2, NOBP, P40 ENSG00000117395 EBNA1 binding protein 2 1 43164175-43270936 Predicted intracellular proteins Evidence at protein level HPA026512, HPA028277 Approved Enhanced Nucleoli Liver cancer:4.22e-4 (unfavourable) Expressed in all Expressed in all testis: 71.8 Expressed in all +CDC20 CDC20A, p55CDC ENSG00000117399 Cell division cycle 20 1 43358955-43363203 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004525, HPA045842, HPA055288 Enhanced Enhanced Nucleus
Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:4.00e-8 (unfavourable), Pancreatic cancer:1.32e-4 (unfavourable) Expressed in all Tissue enhanced testis: 64.0 tonsil: 45.2 Expressed in all +MPL CD110, TPOR ENSG00000117400 MPL proto-oncogene, thrombopoietin receptor 1 43337849-43352772 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Not detected Mixed ovary: 1.3 Cell line enriched 97 HEL: 51.8 +ARTN ENOVIN, EVN, NBN ENSG00000117407 Artemin 1 43933320-43937241 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Ovarian cancer:8.18e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 21.2 seminal vesicle: 12.2 Cell line enhanced A-431: 60.4;HaCaT: 62.8;HBEC3-KT: 45.5 +IPO13 IMP13, KIAA0724, RANBP13 ENSG00000117408 Importin 13 1 43946939-43968022 Predicted intracellular proteins, Transporters Evidence at protein level CAB070425 Uncertain Liver cancer:8.26e-7 (unfavourable), Pancreatic cancer:2.21e-4 (favourable) Expressed in all Expressed in all testis: 66.6 Expressed in all +ATP6V0B ATP6F, HATPL, VMA16 ENSG00000117410 ATPase H+ transporting V0 subunit b 1 43974487-43978295 Predicted membrane proteins Evidence at transcript level HPA044281 Approved Cytosol Renal cancer:3.62e-6 (favourable), Pancreatic cancer:3.24e-4 (favourable), Liver cancer:4.79e-4 (unfavourable), Urothelial cancer:8.87e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 181.4 Expressed in all +B4GALT2 beta4Gal-T2 ENSG00000117411 Beta-1,4-galactosyltransferase 2 1 43978943-43991170 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007620, HPA047739 Enhanced Supported Golgi apparatus
Vesicles Liver cancer:2.96e-5 (unfavourable), Renal cancer:3.62e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 49.4 Mixed +ERI3 FLJ22943, PINT1, PRNPIP ENSG00000117419 ERI1 exoribonuclease family member 3 1 44221070-44355260 Predicted intracellular proteins Evidence at protein level HPA027147, HPA029895 Approved Approved Nucleoplasm
Cytosol Liver cancer:2.04e-6 (unfavourable), Endometrial cancer:1.18e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 81.0 Expressed in all +PTCH2 ENSG00000117425 Patched 2 1 44819844-44843063 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Pancreatic cancer:5.74e-5 (favourable) Tissue enhanced Tissue enriched 6 parathyroid gland: 203.9 salivary gland: 32.2 Cell line enhanced U-266/84: 8.0 +AKR1A1 ALR, DD3 ENSG00000117448 Aldo-keto reductase family 1 member A1 1 45550543-45570049 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB006246, HPA017919, HPA019649, HPA027734 Approved Supported Nucleoplasm
Cytosol Cervical cancer:2.66e-6 (favourable), Endometrial cancer:2.92e-4 (favourable) Expressed in all Expressed in all kidney: 380.4 Expressed in all +PRDX1 NKEFA, PAGA ENSG00000117450 Peroxiredoxin 1 1 45511036-45523047 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004682, HPA007730 Approved Supported Mitochondria Liver cancer:1.17e-5 (unfavourable), Urothelial cancer:2.89e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 1209.9 Expressed in all +PIK3R3 p55 ENSG00000117461 Phosphoinositide-3-kinase regulatory subunit 3 1 46040140-46133036 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA005751, HPA071988 Approved Approved Nucleoplasm
Vesicles Endometrial cancer:1.93e-4 (favourable), Head and neck cancer:3.62e-4 (favourable) Expressed in all Mixed testis: 46.2 Expressed in all +TSPAN1 NET-1, TSPAN-1 ENSG00000117472 Tetraspanin 1 1 46175073-46185958 Predicted membrane proteins Evidence at protein level HPA011909 Approved Approved Nucleoplasm
Vesicles Renal cancer:9.28e-6 (favourable) Expressed in all Tissue enhanced colon: 525.0;rectum: 651.6 prostate: 311.2 Cell line enhanced CAPAN-2: 191.2;HaCaT: 134.4;hTCEpi: 125.3;RPTEC TERT1: 474.4;RT4: 246.2 +BLZF1 JEM-1 ENSG00000117475 Basic leucine zipper nuclear factor 1 1 169367970-169396540 Predicted intracellular proteins Evidence at protein level HPA025703, HPA027331, HPA067113 Supported Supported Nucleus
Golgi apparatus Renal cancer:2.33e-4 (unfavourable) Expressed in all Expressed in all testis: 58.3 Expressed in all +CCDC181 C1orf114, FLJ25846 ENSG00000117477 Coiled-coil domain containing 181 1 169394870-169460669 Predicted intracellular proteins Evidence at protein level HPA027189, HPA027275, HPA027281, HPA027312 Enhanced Approved Nuclear speckles Mixed Tissue enhanced parathyroid gland: 22.9;testis: 49.6 fallopian tube: 19.6 Cell line enhanced NTERA-2: 13.8;SCLC-21H: 9.9;SH-SY5Y: 10.5 +SLC19A2 THTR1, TRMA ENSG00000117479 Solute carrier family 19 member 2 1 169463909-169486003 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA006119, HPA016599 Uncertain Approved Cytosol Renal cancer:2.70e-5 (favourable), Glioma:2.11e-4 (favourable), Breast cancer:8.41e-4 (favourable) Expressed in all Expressed in all gallbladder: 49.2 Mixed +FAAH FAAH-1 ENSG00000117480 Fatty acid amide hydrolase 1 46394265-46413848 Enzymes, Predicted membrane proteins Evidence at protein level HPA007425 Approved Uncertain Cytosol Stomach cancer:3.63e-5 (favourable), Renal cancer:4.25e-5 (favourable), Endometrial cancer:1.51e-4 (favourable) Expressed in all Expressed in all prostate: 60.0 Cell line enhanced BEWO: 34.8;RT4: 31.9 +NSUN4 MGC22960, SHTAP ENSG00000117481 NOP2/Sun RNA methyltransferase family member 4 1 46340177-46365152 Predicted intracellular proteins Evidence at protein level HPA028489 Approved Liver cancer:1.97e-5 (unfavourable) Expressed in all Tissue enriched 14 testis: 98.9 adrenal gland: 7.2 Expressed in all +TMED5 CGI-100, p24g2, p24gamma2 ENSG00000117500 Transmembrane p24 trafficking protein 5 1 93149742-93180728 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA050289 Approved Expressed in all Expressed in all kidney: 28.2 Expressed in all +MROH9 ARMC11, C1orf129, FLJ23550 ENSG00000117501 Maestro heat like repeat family member 9 1 170935471-171064765 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 7 fallopian tube: 3.9;lung: 1.2;testis: 2.7 endometrium: 0.3 Not detected +DR1 NC2-BETA, NC2B ENSG00000117505 Down-regulator of transcription 1 1 93345888-93369498 Predicted intracellular proteins Evidence at protein level HPA050785, HPA055308 Enhanced Supported Nucleus Liver cancer:9.95e-7 (unfavourable), Colorectal cancer:4.79e-4 (favourable), Renal cancer:7.23e-4 (unfavourable), Pancreatic cancer:9.11e-4 (unfavourable) Expressed in all Expressed in all testis: 102.1 Expressed in all +CNN3 ENSG00000117519 Calponin 3 1 94896949-94927278 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009849, HPA051237 Enhanced Enhanced Actin filaments
Cytosol Urothelial cancer:1.99e-4 (unfavourable) Expressed in all Expressed in all placenta: 345.6 Mixed +PRRC2C BAT2D1, BAT2L2, KIAA1096, XTP2 ENSG00000117523 Proline rich coiled-coil 2C 1 171485551-171593511 Predicted intracellular proteins Evidence at protein level HPA025766, HPA028659 Approved Enhanced Cytosol Renal cancer:7.76e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 59.3 Expressed in all +F3 CD142, TF ENSG00000117525 Coagulation factor III, tissue factor 1 94529225-94541800 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009438, HPA049292, HPA069132 Approved Enhanced Vesicles Renal cancer:2.02e-8 (unfavourable), Pancreatic cancer:1.07e-4 (unfavourable) Expressed in all Expressed in all placenta: 191.1 Cell line enhanced A-431: 929.2;HaCaT: 433.2;HBEC3-KT: 914.1;U-2197: 442.4 +ABCD3 PMP70, PXMP1, ZWS2 ENSG00000117528 ATP binding cassette subfamily D member 3 1 94418455-94518666 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA032026, HPA032027, CAB032516, CAB075749 Enhanced Enhanced Peroxisomes Colorectal cancer:1.16e-5 (favourable), Renal cancer:4.84e-5 (favourable) Expressed in all Expressed in all liver: 66.4 Expressed in all +VAMP4 ENSG00000117533 Vesicle associated membrane protein 4 1 171700160-171742247 Predicted membrane proteins Evidence at protein level HPA050418 Enhanced Approved Golgi apparatus Renal cancer:5.43e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 22.4 Expressed in all +DPH5 CGI-30 ENSG00000117543 Diphthamide biosynthesis 5 1 100989623-101026088 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046439, HPA076234 Approved Approved Golgi apparatus Expressed in all Expressed in all ovary: 52.1 Expressed in all +FASLG APT1LG1, CD178, FasL, TNFSF6 ENSG00000117560 Fas ligand 1 172659018-172666874 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level HPA054959 Approved Renal cancer:1.59e-6 (unfavourable) Mixed Tissue enhanced lymph node: 5.8 spleen: 5.1 Not detected +PTBP2 brPTB, nPTB, PTB, PTBLP ENSG00000117569 Polypyrimidine tract binding protein 2 1 96721665-96823738 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047420 Uncertain Approved Nucleoplasm Endometrial cancer:7.80e-4 (unfavourable) Expressed in all Mixed testis: 47.6 Expressed in all +TNFSF4 CD252, gp34, OX-40L, TXGP1 ENSG00000117586 Tumor necrosis factor superfamily member 4 1 173183734-173207313 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA059579 Approved Approved Nucleus
Vesicles Expressed in all Tissue enhanced testis: 7.5 appendix: 3.1 Cell line enhanced fHDF/TERT166: 32.7;HUVEC TERT2: 68.0;LHCN-M2: 56.4 +PRDX6 1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX ENSG00000117592 Peroxiredoxin 6 1 173477266-173488807 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006983, CAB008663 Supported Supported Plasma membrane
Cytosol Head and neck cancer:1.23e-5 (unfavourable), Renal cancer:9.51e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 370.1 Expressed in all +DARS2 FLJ10514 ENSG00000117593 Aspartyl-tRNA synthetase 2, mitochondrial 1 173824503-173858546 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026506, HPA026528 Enhanced Supported Nucleus
Mitochondria Renal cancer:1.74e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 24.9 Expressed in all +HSD11B1 HSD11, HSD11B, SDR26C1 ENSG00000117594 Hydroxysteroid 11-beta dehydrogenase 1 1 209686178-209734950 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA047729 Enhanced Renal cancer:1.97e-10 (unfavourable) Tissue enriched Group enriched 9 liver: 492.5;placenta: 105.1 ovary: 31.6 Group enriched 6 ASC diff: 678.2;HHSteC: 173.0 +IRF6 LPS, OFC6, VWS, VWS1 ENSG00000117595 Interferon regulatory factor 6 1 209785623-209806175 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063121, HPA076162 Enhanced Enhanced Nucleus
Cytosol Renal cancer:0.00e+0 (favourable) Mixed Mixed skin: 84.0 Cell line enhanced HaCaT: 216.2;HBEC3-KT: 62.1;hTCEpi: 129.2;hTERT-HME1: 67.4;RT4: 69.8 +DIEXF C1orf107, DEF, MGC29875, UTP25 ENSG00000117597 Digestive organ expansion factor homolog (zebrafish) 1 209828007-209857565 Predicted intracellular proteins Evidence at protein level HPA026640, HPA061682 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all Mixed ovary: 8.8 Expressed in all +PLPPR5 LPPR5, PAP2, PAP2D, PRG5 ENSG00000117598 Phospholipid phosphatase related 5 1 98890245-99005032 Predicted membrane proteins Evidence at transcript level HPA018072, HPA059085 Uncertain Approved Plasma membrane
Cytosol Renal cancer:6.22e-4 (unfavourable) Group enriched Group enriched 11 cerebral cortex: 12.0;testis: 4.0 adrenal gland: 0.7 Group enriched 7 PC-3: 12.4;SH-SY5Y: 25.0 +PLPPR4 KIAA0455, LPPR4, PHP1, PRG-1 ENSG00000117600 Phospholipid phosphatase related 4 1 99263953-99309590 Enzymes, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enriched 10 cerebral cortex: 88.6 testis: 9.0 Cell line enhanced BJ hTERT+: 21.8;BJ hTERT+ SV40 Large T+ RasG12V: 10.0;SH-SY5Y: 21.1;U-138 MG: 9.8;U-87 MG: 16.4 +SERPINC1 AT3, ATIII, MGC22579 ENSG00000117601 Serpin family C member 1 1 173903804-173917378 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001816, CAB016790, HPA024007 Supported Liver cancer:3.40e-5 (favourable) Tissue enriched Tissue enriched 670 liver: 2517.8 kidney: 3.7 Cell line enriched 26 Hep G2: 55.1 +RCAN3 DSCR1L2 ENSG00000117602 RCAN family member 3 1 24502351-24541040 Predicted intracellular proteins Evidence at protein level HPA034533, HPA064289 Enhanced Approved Nucleoli fibrillar center
Nuclear speckles Expressed in all Tissue enhanced prostate: 54.8 lymph node: 22.9 Mixed +SYF2 CBPIN, DKFZp564O2082, fSAP29, NTC31, p29 ENSG00000117614 SYF2 pre-mRNA splicing factor 1 25222679-25232502 Predicted intracellular proteins Evidence at protein level HPA018265, HPA070710 Approved Supported Nuclear speckles Urothelial cancer:5.72e-4 (favourable) Expressed in all Expressed in all ovary: 135.9 Expressed in all +RSRP1 C1orf63, DJ465N24.2.1 ENSG00000117616 Arginine and serine rich protein 1 1 25242237-25338213 Predicted intracellular proteins Evidence at protein level HPA058992, HPA067651 Uncertain Approved Nucleoplasm Urothelial cancer:2.91e-5 (favourable) Expressed in all Expressed in all adrenal gland: 34.2 Mixed +SLC35A3 ENSG00000117620 Solute carrier family 35 member A3 1 99969351-100035637 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA015253 Uncertain Expressed in all Expressed in all rectum: 58.7 Expressed in all +RCOR3 FLJ10876 ENSG00000117625 REST corepressor 3 1 211258377-211316385 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007413, HPA071997 Enhanced Approved Nucleus
Nucleoli Glioma:1.92e-5 (favourable), Lung cancer:5.75e-5 (favourable) Expressed in all Expressed in all testis: 66.3 Expressed in all +STMN1 C1orf215, FLJ32206, Lag, LAP18, OP18, PP17, PP19, PR22, SMN ENSG00000117632 Stathmin 1 1 25884181-25906991 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB010107 Approved Supported Cytosol Liver cancer:9.90e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1039.4 Expressed in all +MTFR1L FAM54B ENSG00000117640 Mitochondrial fission regulator 1 like 1 25818640-25832942 Predicted intracellular proteins Evidence at protein level HPA027124, HPA027130 Approved Approved Cell Junctions
Mitochondria Renal cancer:5.89e-12 (favourable), Endometrial cancer:6.81e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 150.7 Expressed in all +MAN1C1 HMIC ENSG00000117643 Mannosidase alpha class 1C member 1 1 25617468-25786207 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048352 Uncertain Uncertain Nucleus
Vesicles Pancreatic cancer:4.79e-4 (favourable), Lung cancer:7.55e-4 (favourable) Expressed in all Mixed thyroid gland: 40.7 Cell line enhanced AF22: 28.0;HSkMC: 74.2 +NEK2 NEK2A, NLK1, PPP1R111, RP67 ENSG00000117650 NIMA related kinase 2 1 211658657-211675630 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB017530, HPA064967 Enhanced Supported Nucleus
Centrosome Liver cancer:9.47e-6 (unfavourable), Lung cancer:9.11e-4 (unfavourable) Mixed Tissue enriched 11 testis: 121.2 bone marrow: 11.2 Mixed +RPS6KA1 HU-1, p90Rsk, RSK, RSK1 ENSG00000117676 Ribosomal protein S6 kinase A1 1 26529761-26575030 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003852, HPA007981 Enhanced Supported Nucleus
Cytosol Endometrial cancer:7.20e-7 (favourable), Renal cancer:1.84e-4 (favourable), Stomach cancer:4.58e-4 (favourable), Urothelial cancer:8.33e-4 (favourable) Expressed in all Mixed small intestine: 38.9 Mixed +DHDDS DS, FLJ13102, HDS, RP59 ENSG00000117682 Dehydrodolichyl diphosphate synthase subunit 1 26432282-26471294 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026721, HPA026727 Uncertain Uncertain Plasma membrane Renal cancer:4.08e-7 (favourable) Expressed in all Expressed in all adipose tissue: 54.5 Expressed in all +NENF CIR2, SCIRP10, SPUF ENSG00000117691 Neudesin neurotrophic factor 1 212432887-212446379 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA026763, HPA028488 Uncertain Enhanced Nucleus Renal cancer:1.54e-6 (unfavourable) Expressed in all Expressed in all cervix, uterine: 82.9 Expressed in all +NSL1 C1orf48, DC8, DKFZP566O1646, MIS14 ENSG00000117697 NSL1, MIS12 kinetochore complex component 1 212726153-212791782 Predicted intracellular proteins Evidence at protein level HPA045761, HPA053721 Enhanced Supported Nucleoplasm
Nuclear speckles Expressed in all Expressed in all cerebral cortex: 35.6 Expressed in all +PROX1 ENSG00000117707 Prospero homeobox 1 1 213983181-214041502 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000842, HPA001030 Supported Nucleoplasm Tissue enhanced Tissue enhanced liver: 45.3 adrenal gland: 13.3 Cell line enhanced Hep G2: 21.7;RH-30: 15.7;SH-SY5Y: 83.1 +ARID1A B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1 ENSG00000117713 AT-rich interaction domain 1A 1 26693236-26782104 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005456, CAB016334 Supported Enhanced Nucleoplasm Liver cancer:4.18e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 40.4 Expressed in all +CENPF hcp-1 ENSG00000117724 Centromere protein F 1 214603195-214664588 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052382, HPA064308, CAB070134 Enhanced Supported Nucleoplasm Renal cancer:0.00e+0 (unfavourable), Liver cancer:2.29e-5 (unfavourable), Pancreatic cancer:1.39e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 17.7;testis: 18.8 lymph node: 10.1 Mixed +RPA2 ENSG00000117748 Replication protein A2 1 27891524-27914746 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016538, HPA026306, HPA026309 Supported Enhanced Nucleoplasm
Nuclear bodies Cervical cancer:4.33e-4 (favourable), Head and neck cancer:8.12e-4 (favourable) Expressed in all Expressed in all testis: 103.7 Expressed in all +PPP1R8 ard-1, ARD1, NIPP-1, NIPP1, PRO2047 ENSG00000117751 Protein phosphatase 1 regulatory subunit 8 1 27830778-27851676 Predicted intracellular proteins Evidence at protein level HPA027406, HPA027417, HPA027452 Enhanced Enhanced Nucleoplasm
Nuclear speckles Liver cancer:2.19e-5 (unfavourable) Expressed in all Expressed in all endometrium: 46.5 Expressed in all +STX12 STX13, STX14 ENSG00000117758 Syntaxin 12 1 27773183-27824452 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041038, HPA055300 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Expressed in all Expressed in all thyroid gland: 156.0 Expressed in all +MARC2 FLJ20605, MOSC2 ENSG00000117791 Mitochondrial amidoxime reducing component 2 1 220748225-220784815 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015085, HPA017572 Enhanced Liver cancer:1.40e-10 (favourable), Renal cancer:3.09e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 338.5 kidney: 139.5 Cell line enhanced T-47d: 33.9 +SLC5A9 SGLT4 ENSG00000117834 Solute carrier family 5 member 9 1 48222685-48248644 Predicted membrane proteins, Transporters Evidence at protein level HPA050263 Approved Actin filaments
Cytosol Renal cancer:1.84e-5 (unfavourable) Tissue enhanced Group enriched 9 duodenum: 42.6;small intestine: 45.5 lung: 4.6 Cell line enriched 7 Hep G2: 10.2 +OSBPL9 ENSG00000117859 Oxysterol binding protein like 9 1 51577179-51798427 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027378, HPA027397 Supported Approved Supported Golgi apparatus
Vesicles Expressed in all Expressed in all parathyroid gland: 96.6 Expressed in all +TXNDC12 AGR1, ERP18, ERP19, hAG-1, PDIA16, TLP19 ENSG00000117862 Thioredoxin domain containing 12 1 52020131-52056171 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.40e-12 (unfavourable), Liver cancer:1.28e-5 (unfavourable), Head and neck cancer:2.61e-4 (unfavourable), Colorectal cancer:4.44e-4 (favourable) Expressed in all Expressed in all fallopian tube: 49.8 Expressed in all +ESYT2 CHR2SYT, FAM62B, KIAA1228 ENSG00000117868 Extended synaptotagmin 2 7 158730995-158830253 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA002132 Approved Uncertain Cytosol Urothelial cancer:2.81e-5 (unfavourable), Pancreatic cancer:5.73e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 80.2 Expressed in all +CD3EAP ASE-1, CAST, PAF49 ENSG00000117877 CD3e molecule associated protein 19 45406209-45410766 Predicted intracellular proteins Evidence at protein level HPA041664, HPA041734 Supported Enhanced Nucleus
Nucleoli fibrillar center
Mitochondria Liver cancer:4.79e-9 (unfavourable) Expressed in all Mixed appendix,cerebral cortex: 5.4 Expressed in all +MESDC2 BOCA, KIAA0081, MESD ENSG00000117899 Mesoderm development candidate 2 15 80946289-80989878 Predicted secreted proteins Evidence at protein level HPA039414, HPA041721 Approved Supported Nuclear bodies
Endoplasmic reticulum
Cytosol Ovarian cancer:1.12e-4 (favourable), Endometrial cancer:2.31e-4 (favourable) Expressed in all Expressed in all thyroid gland: 55.7 Expressed in all +RCN2 E6BP, ERC-55, ERC55, TCBP49 ENSG00000117906 Reticulocalbin 2 15 76931619-76954392 Predicted secreted proteins Evidence at protein level HPA030694, HPA030695 Enhanced Supported Enhanced Endoplasmic reticulum Liver cancer:7.36e-5 (unfavourable) Expressed in all Expressed in all epididymis: 391.5 Expressed in all +CHRNB4 ENSG00000117971 Cholinergic receptor nicotinic beta 4 subunit 15 78624119-78727754 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced adrenal gland: 3.2;testis: 5.3 appendix: 0.8 Group enriched 23 SCLC-21H: 34.9;SH-SY5Y: 40.9 +MUC5B MG1, MUC5 ENSG00000117983 Mucin 5B, oligomeric mucus/gel-forming 11 1223066-1262172 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008246, CAB009396 Enhanced Supported Vesicles Mixed Group enriched 11 cervix, uterine: 350.5;gallbladder: 344.7 colon: 31.8 Cell line enriched 7 PC-3: 111.2 +CTSD CLN10, CPSD ENSG00000117984 Cathepsin D 11 1752752-1764573 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000109, HPA003001 Enhanced Renal cancer:4.93e-5 (favourable), Colorectal cancer:2.46e-4 (unfavourable) Expressed in all Expressed in all lung: 1026.9 Expressed in all +COLEC11 CL-K1, MGC3279 ENSG00000118004 Collectin subfamily member 11 2 3594832-3644644 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035241 Approved Tissue enhanced Tissue enhanced gallbladder: 102.0 adrenal gland: 36.2 Group enriched 8 HHSteC: 135.6;SH-SY5Y: 158.1 +STAG1 SA-1, SA1, SCC3A ENSG00000118007 Stromal antigen 1 3 136336233-136752403 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035015, HPA058653 Supported Enhanced Nucleus
Nuclear bodies Expressed in all Expressed in all endometrium: 31.9 Expressed in all +A4GNT alpha4GnT ENSG00000118017 Alpha-1,4-N-acetylglucosaminyltransferase 3 138123718-138132387 Predicted secreted proteins Evidence at protein level HPA008017 Enhanced Group enriched Tissue enriched 8 stomach: 24.5 gallbladder: 3.2 Not detected +STK11 LKB1, PJS ENSG00000118046 Serine/threonine kinase 11 19 1177558-1228435 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB016231, HPA017254, CAB022105, HPA067481 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:3.69e-5 (favourable), Head and neck cancer:1.96e-4 (favourable) Expressed in all Expressed in all testis: 77.1 Mixed +KMT2A ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1 ENSG00000118058 Lysine methyltransferase 2A 11 118436490-118526832 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017794, CAB024270, HPA044910 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 31.0 Expressed in all +TREH MGC129621, TRE, TREA ENSG00000118094 Trehalase 11 118657316-118679690 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA039913, HPA042045 Enhanced Renal cancer:2.33e-6 (favourable), Liver cancer:3.76e-4 (favourable) Mixed Tissue enhanced duodenum: 60.6;small intestine: 72.6 kidney: 13.5 Cell line enhanced BEWO: 1.5 +IFT46 C11orf2, C11orf60, CFAP32, FLJ21827 ENSG00000118096 Intraflagellar transport 46 11 118544528-118572970 Predicted intracellular proteins Evidence at protein level HPA037909, HPA057550 Approved Approved Actin filaments Expressed in all Expressed in all fallopian tube: 97.3 Expressed in all +MMP8 CLG1 ENSG00000118113 Matrix metallopeptidase 8 11 102711795-102727050 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021221, HPA022935 Enhanced Tissue enriched Tissue enriched 103 bone marrow: 335.8 endometrium: 3.2 Cell line enriched 10 WM-115: 69.6 +APOA1 ENSG00000118137 Apolipoprotein A1 11 116835751-116837950 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016778, HPA046715 Supported Approved Vesicles
Cytosol Renal cancer:1.67e-8 (unfavourable), Liver cancer:5.05e-4 (favourable) Tissue enriched Tissue enhanced liver: 8458.6;small intestine: 4128.6 duodenum: 1609.4 Cell line enriched 15 Hep G2: 1951.8 +ZNF541 DKFZp434I1930 ENSG00000118156 Zinc finger protein 541 19 47520685-47555856 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058541, HPA076453 Enhanced Approved Nucleoplasm
Cytosol Cervical cancer:2.94e-4 (favourable) Tissue enhanced Tissue enriched 11 testis: 19.2 ovary: 1.7 Group enriched 6 HEL: 1.4;SiHa: 5.3;U-87 MG: 1.6 +SLC8A2 KIAA1087, NCX2 ENSG00000118160 Solute carrier family 8 member A2 19 47428017-47472168 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA050818, HPA054671 Enhanced Mixed Tissue enriched 11 cerebral cortex: 68.2 endometrium: 6.3 Group enriched 8 NTERA-2: 3.2;SCLC-21H: 10.8;SH-SY5Y: 5.2;SiHa: 4.1;U-2 OS: 6.2 +KPTN 2E4 ENSG00000118162 Kaptin, actin binding protein 19 47475144-47484268 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041710, HPA041796 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:7.91e-6 (unfavourable), Renal cancer:7.82e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 7.9 Expressed in all +RPS25 S25 ENSG00000118181 Ribosomal protein S25 11 119015712-119018691 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA031801 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:3.00e-7 (unfavourable) Expressed in all Expressed in all ovary: 945.5 Expressed in all +KIF14 KIAA0042 ENSG00000118193 Kinesin family member 14 1 200551497-200620734 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038061, HPA058220 Uncertain Supported Midbody ring
Cytosol Lung cancer:8.64e-4 (unfavourable) Mixed Mixed testis: 4.6 Mixed +TNNT2 CMD1D, CMH2, CMPD2 ENSG00000118194 Troponin T2, cardiac type 1 201359008-201377762 Candidate cardiovascular disease genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015371, HPA015774, HPA017888 Enhanced Uncertain Nucleus
Nucleoli
Focal adhesion sites Mixed Tissue enriched 203 heart muscle: 5120.1 skin: 25.2 Cell line enriched 30 RH-30: 1495.9 +DDX59 DKFZP564B1023, ZNHIT5 ENSG00000118197 DEAD-box helicase 59 1 200623896-200669969 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA047166 Approved Approved Nucleus
Actin filaments Renal cancer:9.02e-4 (unfavourable) Expressed in all Expressed in all breast: 33.4 Expressed in all +CAMSAP2 CAMSAP1L1, KIAA1078 ENSG00000118200 Calmodulin regulated spectrin associated protein family member 2 1 200739558-200860704 Predicted intracellular proteins Evidence at protein level HPA026304, HPA026511, HPA027302 Enhanced Supported Microtubule ends
Cytosol Liver cancer:2.11e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 64.5 Cell line enhanced hTERT-HME1: 124.5 +ATF6 ATF6A ENSG00000118217 Activating transcription factor 6 1 161766294-161964070 Disease related genes, Plasma proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA005935 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 41.3 Expressed in all +CRYGD CRYG4 ENSG00000118231 Crystallin gamma D 2 208121607-208124501 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041269 Approved Plasma membrane
Intermediate filaments
Cytokinetic bridge Tissue enhanced Tissue enriched 13 ovary: 21.6 bone marrow: 1.6 Cell line enriched 17 HEL: 19.0 +MREG DSU, FLJ10116, WDT2 ENSG00000118242 Melanoregulin 2 215942805-216034096 Predicted intracellular proteins Evidence at protein level HPA068583 Approved Vesicles Thyroid cancer:4.20e-4 (favourable) Expressed in all Mixed esophagus: 29.4 Cell line enhanced MCF7: 74.2 +TNP1 ENSG00000118245 Transition protein 1 2 216859458-216860064 Predicted intracellular proteins Evidence at protein level HPA044387 Enhanced Group enriched Tissue enriched 2184 testis: 4403.1 thyroid gland: 2.0 Cell line enhanced Hep G2: 1.7;U-2197: 1.0 +FASTKD2 KIAA0971 ENSG00000118246 FAST kinase domains 2 2 206765357-206792509 Predicted intracellular proteins Evidence at protein level HPA067191 Supported Mitochondria Liver cancer:8.29e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 30.2 Expressed in all +NRP2 VEGF165R2 ENSG00000118257 Neuropilin 2 2 205681990-205798133 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA039980, HPA054974 Enhanced Supported Vesicles
Plasma membrane Renal cancer:7.68e-7 (unfavourable), Urothelial cancer:7.80e-5 (unfavourable) Expressed in all Mixed smooth muscle: 84.4 Cell line enhanced CAPAN-2: 119.6;U-251 MG: 195.9 +CREB1 ENSG00000118260 CAMP responsive element binding protein 1 2 207529737-207603431 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003803, HPA019150 Supported Enhanced Nucleoplasm Liver cancer:2.77e-5 (unfavourable) Expressed in all Expressed in all testis: 59.1 Expressed in all +KLF7 UKLF ENSG00000118263 Kruppel like factor 7 2 207074137-207167267 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA030490 Approved Approved Golgi apparatus Renal cancer:4.26e-4 (favourable) Expressed in all Expressed in all smooth muscle: 30.5 Mixed +TTR CTS, CTS1, HsT2651, PALB ENSG00000118271 Transthyretin 18 31591726-31599021 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB002517, HPA002550, CAB062567, CAB073406 Supported Approved Golgi apparatus Group enriched Tissue enriched 27 liver: 6343.2 pancreas: 235.0 Group enriched 7 CACO-2: 68.3;EFO-21: 26.5;Hep G2: 87.1;U-2 OS: 38.2 +B4GALT6 beta4GalT-VI ENSG00000118276 Beta-1,4-galactosyltransferase 6 18 31622247-31685836 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB020701, HPA058284 Approved Renal cancer:6.40e-5 (favourable), Pancreatic cancer:5.65e-4 (favourable) Expressed in all Mixed cerebral cortex: 21.6 Cell line enhanced WM-115: 124.6 +C1orf54 FLJ23221 ENSG00000118292 Chromosome 1 open reading frame 54 1 150268200-150280916 Predicted secreted proteins Evidence at transcript level HPA026518, HPA043874 Approved Approved Plasma membrane Renal cancer:2.43e-4 (unfavourable) Expressed in all Expressed in all spleen: 76.0 Cell line enhanced AF22: 61.4;AN3-CA: 87.4;ASC TERT1: 75.6;HSkMC: 63.9;HUVEC TERT2: 73.1 +CA14 ENSG00000118298 Carbonic anhydrase 14 1 150257159-150265078 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008482 Approved Approved Plasma membrane Group enriched Tissue enhanced cerebral cortex: 10.6;seminal vesicle: 21.2 skeletal muscle: 9.4 Group enriched 23 AF22: 83.4;AN3-CA: 46.6;NTERA-2: 65.8;SK-MEL-30: 134.5 +CASC1 FLJ10921, LAS1, PPP1R54 ENSG00000118307 Cancer susceptibility 1 12 25108420-25195162 Predicted intracellular proteins Evidence at protein level HPA039662 Enhanced Renal cancer:3.13e-4 (favourable) Mixed Tissue enhanced fallopian tube: 22.5;testis: 41.8 thyroid gland: 7.0 Mixed +LRMP JAW1 ENSG00000118308 Lymphoid restricted membrane protein 12 25004342-25108334 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002967, HPA018505 Enhanced Supported Nucleus
Vesicles
Cytosol Mixed Tissue enhanced lymph node: 207.1;tonsil: 185.6 appendix: 63.4 Group enriched 7 Daudi: 453.9;REH: 202.5;U-698: 497.6 +ATP10B ATPVB, FLJ21477, KIAA0715 ENSG00000118322 ATPase phospholipid transporting 10B (putative) 5 160563120-160852214 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034574 Uncertain Group enriched Tissue enhanced colon: 36.0;rectum: 40.3 gallbladder: 21.4 Cell line enriched 23 WM-115: 13.6 +SPCS2 KIAA0102 ENSG00000118363 Signal peptidase complex subunit 2 11 74949247-74979031 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013386 Approved Approved Nucleus Expressed in all Expressed in all epididymis: 269.1 Expressed in all +USP35 KIAA1372 ENSG00000118369 Ubiquitin specific peptidase 35 11 78188812-78214711 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055213, HPA058592 Uncertain Approved Nucleus
Nucleoli fibrillar center Expressed in all Tissue enhanced parathyroid gland: 34.3 adrenal gland: 14.8 Expressed in all +ELOVL4 CT118, SCA34, STGD2, STGD3 ENSG00000118402 ELOVL fatty acid elongase 4 6 79914812-79947580 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Urothelial cancer:6.27e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 24.0;skin: 50.7 parathyroid gland: 15.7 Cell line enhanced MOLT-4: 25.9 +FILIP1 FILIP, KIAA1275 ENSG00000118407 Filamin A interacting protein 1 6 75291859-75493738 Predicted intracellular proteins Evidence at protein level HPA053564 Enhanced Uncertain Plasma membrane
Actin filaments Mixed Tissue enhanced heart muscle: 35.3 smooth muscle: 19.5 Cell line enhanced EFO-21: 6.6;U-266/70: 5.3 +CASP8AP2 CED-4, FLASH, FLJ11208, KIAA1315, RIP25 ENSG00000118412 Caspase 8 associated protein 2 6 89829894-89874436 Predicted intracellular proteins Evidence at protein level HPA053573 Approved Nucleoli
Nuclear bodies Renal cancer:1.88e-5 (unfavourable) Expressed in all Mixed lymph node: 6.4 Expressed in all +HMGN3 TRIP7 ENSG00000118418 High mobility group nucleosomal binding domain 3 6 79201245-79234738 Predicted intracellular proteins Evidence at protein level CAB018370, HPA027971, HPA063572 Enhanced Enhanced Nucleus
Cytosol Renal cancer:1.02e-7 (unfavourable), Lung cancer:2.76e-4 (favourable) Expressed in all Expressed in all fallopian tube: 335.7 Mixed +UBE3D C6orf157, DKFZp434A1520, H10BH, UBE2CBP, YJR141W ENSG00000118420 Ubiquitin protein ligase E3D 6 82892398-83065841 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027231 Uncertain Approved Rods & Rings Mixed Mixed fallopian tube: 6.3 Expressed in all +CNR1 CANN6, CB-R, CB1, CB1A, CB1K5, CNR ENSG00000118432 Cannabinoid receptor 1 6 88139864-88166359 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Tissue enhanced cerebral cortex: 32.1 adipose tissue: 12.2 Group enriched 7 ASC diff: 55.8;HSkMC: 39.1 +SPACA1 SAMP32 ENSG00000118434 Sperm acrosome associated 1 6 88047789-88066832 Predicted membrane proteins Evidence at protein level HPA026744, HPA043297 Enhanced Not detected Tissue enriched 512 testis: 51.2 all non-specific tissues: 0.0 Not detected +ANKRD13C dJ677H15.3, DKFZP566D1346 ENSG00000118454 Ankyrin repeat domain 13C 1 70260588-70354734 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all parathyroid gland: 19.1 Expressed in all +SGIP1 DKFZp761D221 ENSG00000118473 SH3 domain GRB2 like endophilin interacting protein 1 1 66533383-66748299 Predicted intracellular proteins Evidence at protein level HPA017963 Approved Approved Mitochondria Mixed Tissue enhanced cerebral cortex: 36.2 endometrium: 16.9 Cell line enhanced BJ: 24.8;BJ hTERT+: 30.5;fHDF/TERT166: 18.7;RPTEC TERT1: 20.7;SH-SY5Y: 15.7;U-138 MG: 26.6 +PHF3 ENSG00000118482 PHD finger protein 3 6 63635820-63779336 Predicted intracellular proteins Evidence at protein level HPA024676, HPA025763 Approved Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 48.5 Expressed in all +ZC2HC1B C6orf94, dJ468K18.5, FAM164B ENSG00000118491 Zinc finger C2HC-type containing 1B 6 143864436-143938356 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 74 testis: 23.4 skin: 0.3 Not detected +ADGB C6orf103, CAPN16, dJ408K24.1, FLJ23121 ENSG00000118492 Androglobin 6 146598965-146815462 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036340, HPA036341 Enhanced Uncertain Nucleoplasm
Mitochondria Not detected Group enriched 25 fallopian tube: 14.9;testis: 58.5 lung: 1.4 Cell line enriched 25 HDLM-2: 13.3 +PLAGL1 LOT1, ZAC ENSG00000118495 PLAG1 like zinc finger 1 6 143940300-144064599 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055706 Supported Nuclear bodies
Golgi apparatus
Vesicles Renal cancer:4.94e-6 (unfavourable), Stomach cancer:6.61e-4 (unfavourable) Mixed Tissue enriched 5 placenta: 365.4 skin: 72.8 Cell line enhanced AF22: 105.6;RH-30: 105.2 +FBXO30 Fbx30, MGC21674 ENSG00000118496 F-box protein 30 6 145793502-145814753 Predicted intracellular proteins Evidence at protein level HPA012583 Approved Microtubules Expressed in all Mixed thyroid gland: 13.5 Expressed in all +TNFAIP3 A20, OTUD7C ENSG00000118503 TNF alpha induced protein 3 6 137867188-137883312 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002116, HPA067479 Approved Supported Vesicles Renal cancer:6.05e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 345.2 Cell line enhanced Karpas-707: 118.8;REH: 135.9 +AKAP7 AKAP15, AKAP18 ENSG00000118507 A-kinase anchoring protein 7 6 131135666-131283535 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027172, HPA028327 Approved Urothelial cancer:2.56e-4 (favourable) Expressed in all Expressed in all adrenal gland: 72.6 Cell line enhanced NTERA-2: 27.0 +RAB32 ENSG00000118508 RAB32, member RAS oncogene family 6 146543693-146554965 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025731 Approved Approved Cytosol Liver cancer:1.08e-7 (unfavourable), Colorectal cancer:1.56e-4 (favourable), Endometrial cancer:6.51e-4 (unfavourable), Renal cancer:8.62e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 91.9 Mixed +MYB c-myb ENSG00000118513 MYB proto-oncogene, transcription factor 6 135181315-135219173 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017704 Approved Approved Nucleus
Plasma membrane Prostate cancer:9.65e-4 (favourable), Stomach cancer:9.87e-4 (favourable) Tissue enhanced Tissue enhanced breast: 26.3;rectum: 29.1 colon: 25.2 Cell line enhanced HL-60: 173.9;MOLT-4: 321.7;REH: 222.8;THP-1: 230.7;U-937: 145.8 +ALDH8A1 ALDH12 ENSG00000118514 Aldehyde dehydrogenase 8 family member A1 6 134917390-134950122 Predicted intracellular proteins Evidence at protein level HPA026292, HPA055414 Enhanced Supported Centrosome Renal cancer:9.87e-4 (favourable) Group enriched Group enriched 29 kidney: 74.3;liver: 127.7 cerebral cortex: 3.4 Mixed +SGK1 SGK ENSG00000118515 Serum/glucocorticoid regulated kinase 1 6 134169246-134318112 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB022085, CAB025148, HPA051251 Approved Enhanced Nuclear speckles Cervical cancer:5.26e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 793.4 Cell line enhanced RPTEC TERT1: 354.6;TIME: 304.3 +RNF146 dactylidin, dJ351K20.1, DKFZp434O1427 ENSG00000118518 Ring finger protein 146 6 127266610-127288567 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027158, HPA027209 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:5.26e-5 (favourable), Renal cancer:7.32e-4 (favourable) Expressed in all Expressed in all endometrium: 94.6 Expressed in all +ARG1 ENSG00000118520 Arginase 1 6 131573144-131584332 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003595, CAB009434, HPA024006, CAB056159 Enhanced Tissue enriched Tissue enhanced bone marrow: 171.2;liver: 566.2 skin: 78.2 Not detected +CTGF CCN2, IGFBP8 ENSG00000118523 Connective tissue growth factor 6 131948176-131951373 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB005123, HPA031075 Approved Stomach cancer:5.04e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 845.3 Cell line enhanced EFO-21: 1511.7;HUVEC TERT2: 1148.6;TIME: 2338.5 +TCF21 bHLHa23, POD1 ENSG00000118526 Transcription factor 21 6 133889138-133895553 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA013189 Uncertain Mixed Tissue enhanced placenta: 62.4;spleen: 46.9 ovary: 32.1 Cell line enriched 10 HHSteC: 13.5 +PMFBP1 ENSG00000118557 Polyamine modulated factor 1 binding protein 1 16 72112157-72176878 Predicted intracellular proteins Evidence at protein level HPA056716 Approved Endoplasmic reticulum Mixed Tissue enhanced epididymis: 16.0;testis: 32.3 skin: 5.3 Cell line enhanced SCLC-21H: 25.3;SH-SY5Y: 11.4 +FBXL5 FBL4, FBL5, FLR1 ENSG00000118564 F-box and leucine rich repeat protein 5 4 15604539-15681679 Predicted intracellular proteins Evidence at protein level Renal cancer:6.18e-5 (favourable) Expressed in all Expressed in all kidney: 135.1 Expressed in all +MED28 DKFZP434N185, EG1, magicin ENSG00000118579 Mediator complex subunit 28 4 17614631-17634105 Predicted intracellular proteins Evidence at protein level HPA035900, HPA035901 Uncertain Supported Nucleoplasm Expressed in all Mixed endometrium: 19.0 Expressed in all +SLC16A7 MCT2 ENSG00000118596 Solute carrier family 16 member 7 12 59596067-59789855 Predicted membrane proteins, Transporters Evidence at protein level HPA005911 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:8.85e-5 (favourable) Mixed Mixed adipose tissue,heart muscle: 24.9 Mixed +TMEM5 HP10481 ENSG00000118600 Transmembrane protein 5 12 63779803-63809558 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064014 Approved Nucleoplasm
Golgi apparatus Liver cancer:5.24e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.5 Expressed in all +ZNF430 FLJ13659 ENSG00000118620 Zinc finger protein 430 19 21020620-21060050 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059135 Uncertain Mixed Mixed ovary: 15.8 Mixed +VAMP8 EDB ENSG00000118640 Vesicle associated membrane protein 8 2 85561562-85582031 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA006882, CAB037132, CAB037147 Enhanced Thyroid cancer:8.07e-9 (favourable), Urothelial cancer:1.59e-6 (favourable) Expressed in all Expressed in all lung: 327.6 Cell line enhanced HL-60: 584.2;NB-4: 722.5;U-937: 587.5 +DCLRE1B FLJ12810, FLJ13998, SNM1B ENSG00000118655 DNA cross-link repair 1B 1 113905141-113914086 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064934 Supported Nucleoplasm
Nuclear bodies Renal cancer:5.03e-7 (unfavourable), Liver cancer:4.50e-5 (unfavourable), Pancreatic cancer:6.70e-4 (unfavourable) Expressed in all Mixed spleen: 5.4 Expressed in all +MYL12B MRLC2 ENSG00000118680 Myosin light chain 12B 18 3261909-3278284 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039262, HPA045244, HPA059197 Supported Approved Nucleus
Nucleoli fibrillar center Thyroid cancer:6.62e-6 (favourable), Renal cancer:8.17e-5 (favourable), Pancreatic cancer:9.69e-4 (unfavourable) Expressed in all Expressed in all epididymis: 586.9 Expressed in all +FOXO3 AF6q21, FKHRL1, FOXO2, FOXO3A ENSG00000118689 Forkhead box O3 6 108559835-108684774 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004074, HPA063104 Supported Enhanced Nucleus Expressed in all Expressed in all ovary: 55.1 Expressed in all +ARMC2 bA787I22.1, DKFZp434P0714 ENSG00000118690 Armadillo repeat containing 2 6 108848416-108974472 Predicted intracellular proteins Evidence at protein level HPA025809, HPA053696 Enhanced Approved Nucleus Mixed Tissue enhanced testis: 62.0 fallopian tube: 33.6 Expressed in all +GHRH GHRF ENSG00000118702 Growth hormone releasing hormone 20 37251082-37261835 Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enhanced adrenal gland: 1.4;duodenum: 3.4 small intestine: 1.2 Cell line enhanced NTERA-2: 2.0;U-266/84: 5.4 +RPN2 RIBIIR, RPN-II, RPNII, SWP1 ENSG00000118705 Ribophorin II 20 37178410-37241623 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008297, CAB019277, HPA025922 Enhanced Supported Endoplasmic reticulum Renal cancer:1.44e-10 (unfavourable), Liver cancer:1.38e-4 (unfavourable), Urothelial cancer:2.44e-4 (unfavourable) Expressed in all Expressed in all epididymis: 364.2 Expressed in all +TGIF2 ENSG00000118707 TGFB induced factor homeobox 2 20 36573488-36593950 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053786 Supported Nucleoplasm Expressed in all Mixed fallopian tube: 38.3 Mixed +CASQ2 PDIB2 ENSG00000118729 Calsequestrin 2 1 115700007-115768781 Disease related genes, Predicted secreted proteins Evidence at protein level HPA027285, HPA055298 Enhanced Urothelial cancer:2.25e-5 (unfavourable), Head and neck cancer:2.30e-4 (unfavourable) Mixed Tissue enriched 11 heart muscle: 679.4 skeletal muscle: 62.3 Cell line enriched 14 HSkMC: 9.6 +OLFM3 NOE3 ENSG00000118733 Olfactomedin 3 1 101802574-101997030 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA050297 Uncertain Vesicles Mixed Tissue enriched 15 cerebral cortex: 26.7 adrenal gland: 1.8 Group enriched 11 AF22: 5.5;HAP1: 4.0;HEL: 3.2;SCLC-21H: 2.6;SH-SY5Y: 2.3 +PKD2 Pc-2, PC2, PKD4, TRPP2 ENSG00000118762 Polycystin 2, transient receptor potential cation channel 4 88007668-88077777 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB004544, HPA015794 Approved Enhanced Endoplasmic reticulum Expressed in all Expressed in all endometrium: 101.0 Cell line enhanced BJ hTERT+: 167.9 +ABCG2 ABCP, BCRP, CD338, EST157481, MXR ENSG00000118777 ATP binding cassette subfamily G member 2 (Junior blood group) 4 88090264-88231322 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB037299, HPA054719 Enhanced Enhanced Nucleus
Plasma membrane Mixed Tissue enhanced small intestine: 113.8 seminal vesicle: 55.9 Cell line enhanced A549: 47.2;BEWO: 80.5;RPMI-8226: 32.5 +SPP1 BNSP, BSPI, ETA-1, OPN ENSG00000118785 Secreted phosphoprotein 1 4 87975650-87983426 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB002212, HPA027540, HPA027541 Enhanced Supported Golgi apparatus Liver cancer:2.84e-6 (unfavourable), Pancreatic cancer:5.89e-4 (unfavourable), Cervical cancer:9.52e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 3987.0;kidney: 2404.4;placenta: 4045.7 cerebral cortex: 795.2 Group enriched 6 EFO-21: 4669.3;Hep G2: 1742.5;RPTEC TERT1: 8242.5 +STBD1 FLJ41801, GENX-3414 ENSG00000118804 Starch binding domain 1 4 76306026-76311599 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA011952, HPA012849 Enhanced Supported Cytosol Mixed Tissue enhanced adipose tissue: 46.7;skeletal muscle: 32.8 liver: 14.5 Cell line enhanced HDLM-2: 24.3;Karpas-707: 37.9;U-266/70: 25.8 +CCNI CCNI1 ENSG00000118816 Cyclin I 4 77047158-77076005 Predicted intracellular proteins Evidence at protein level CAB010206, HPA039853, HPA061470 Uncertain Supported Nucleoplasm
Nuclear bodies
Golgi apparatus Renal cancer:2.10e-4 (favourable) Expressed in all Expressed in all thyroid gland: 453.5 Expressed in all +RARRES1 LXNL, TIG1 ENSG00000118849 Retinoic acid receptor responder 1 3 158696892-158732696 Predicted secreted proteins Evidence at protein level HPA003892 Uncertain Approved Endoplasmic reticulum
Golgi apparatus Renal cancer:5.88e-6 (unfavourable) Expressed in all Mixed appendix: 78.0 Cell line enriched 11 CAPAN-2: 1010.9 +MFSD1 FLJ14153, UG0581B09 ENSG00000118855 Major facilitator superfamily domain containing 1 3 158732198-158829719 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA057924, HPA065858 Approved Approved Nucleus
Nucleoli Renal cancer:5.60e-5 (favourable) Expressed in all Expressed in all spleen: 35.2 Expressed in all +RAB3GAP2 DKFZP434D245, KIAA0839, RAB3-GAP150, SPG69 ENSG00000118873 RAB3 GTPase activating non-catalytic protein subunit 2 1 220148293-220272454 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026273, HPA027299 Approved Supported Plasma membrane
Cytosol Breast cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.9 Expressed in all +EEF2KMT EFM3, FAM86A, MGC19636, SB153 ENSG00000118894 Eukaryotic elongation factor 2 lysine methyltransferase 16 5084304-5097808 Predicted intracellular proteins Evidence at protein level HPA041610 Approved Uncertain Vesicles Urothelial cancer:2.35e-4 (unfavourable), Liver cancer:8.85e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 11.3 Expressed in all +PPL ENSG00000118898 Periplakin 16 4882507-4960741 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042550, HPA059859 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Ovarian cancer:2.76e-4 (unfavourable) Expressed in all Group enriched 7 esophagus: 558.8;skin: 149.5 tonsil: 52.0 Cell line enhanced HaCaT: 168.9;SiHa: 108.6 +UBN1 ENSG00000118900 Ubinuclein 1 16 4846665-4882360 Predicted intracellular proteins Evidence at protein level HPA061029, HPA069045 Enhanced Supported Nucleoplasm
Nuclear bodies Pancreatic cancer:3.84e-4 (unfavourable) Expressed in all Expressed in all testis: 70.4 Expressed in all +KLF12 AP-2rep, AP2REP, HSPC122 ENSG00000118922 Kruppel like factor 12 13 73686089-73995056 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA064146 Approved Nucleoplasm
Cytosol Endometrial cancer:5.03e-6 (unfavourable) Expressed in all Mixed epididymis: 13.7 Mixed +UCHL3 ENSG00000118939 Ubiquitin C-terminal hydrolase L3 13 75549480-75606020 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019678, CAB037139, CAB037208 Approved Supported Nucleus
Cytosol Liver cancer:6.41e-4 (unfavourable) Expressed in all Expressed in all testis: 90.7 Expressed in all +PCDH17 PCDH68, PCH68 ENSG00000118946 Protocadherin 17 13 57631810-57729311 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026817 Uncertain Approved Vesicles
Plasma membrane
Cytosol Renal cancer:3.31e-5 (unfavourable) Mixed Tissue enhanced cerebral cortex: 25.8;spleen: 33.8 lung: 18.3 Cell line enhanced AF22: 13.8;HEK 293: 8.1;U-87 MG: 5.1 +HS1BP3 FLJ14249, HS1-BP3 ENSG00000118960 HCLS1 binding protein 3 2 20560448-20651089 Predicted intracellular proteins Evidence at protein level HPA035050 Approved Approved Nucleoli
Cytosol Liver cancer:2.97e-5 (unfavourable), Renal cancer:2.30e-4 (favourable) Expressed in all Expressed in all adrenal gland: 33.3 Expressed in all +LDAH C2orf43, FLJ21820 ENSG00000118961 Lipid droplet associated hydrolase 2 20684014-20823130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034729, HPA034730 Approved Uncertain Nuclear speckles
Cytosol Liver cancer:6.09e-6 (unfavourable), Renal cancer:1.18e-4 (favourable) Expressed in all Mixed parathyroid gland: 20.6 Mixed +WDR35 IFT121, IFTA1, KIAA1336, MGC33196 ENSG00000118965 WD repeat domain 35 2 19910260-19990131 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044147 Approved Expressed in all Mixed parathyroid gland: 26.2 Mixed +CCND2 ENSG00000118971 Cyclin D2 12 4273772-4305350 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049138, HPA054196 Approved Supported Nucleoplasm Thyroid cancer:9.76e-5 (favourable), Pancreatic cancer:2.52e-4 (favourable) Expressed in all Mixed epididymis: 55.9 Cell line enhanced AF22: 155.7;HDLM-2: 235.1;Karpas-707: 252.4;RH-30: 221.5 +FGF23 ENSG00000118972 Fibroblast growth factor 23 12 4368227-4379728 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Not detected Mixed epididymis: 1.5 Cell line enhanced AF22: 1.9 +ELL2 ENSG00000118985 Elongation factor for RNA polymerase II 2 5 95885098-95962071 Predicted intracellular proteins Evidence at protein level HPA013569 Supported Nucleoplasm Renal cancer:1.31e-4 (unfavourable), Stomach cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all skin: 69.0 Cell line enhanced BJ: 267.9;HDLM-2: 265.3 +DNAH7 KIAA0944 ENSG00000118997 Dynein axonemal heavy chain 7 2 195737703-196068812 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034724, HPA044070 Approved Supported Cytosol Not detected Tissue enhanced fallopian tube: 15.6;testis: 18.1 thyroid gland: 4.6 Cell line enhanced PC-3: 5.5 +CYP20A1 CYP-M ENSG00000119004 Cytochrome P450 family 20 subfamily A member 1 2 203238940-203305611 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055872, HPA058461 Uncertain Approved Plasma membrane
Cell Junctions
Actin filaments Expressed in all Mixed thyroid gland: 16.4 Mixed +NDUFB3 B12 ENSG00000119013 NADH:ubiquinone oxidoreductase subunit B3 2 201071433-201085750 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034596 Approved Head and neck cancer:7.24e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 180.0 Expressed in all +GTF3C3 TFIIIC102, TFiiiC2-102 ENSG00000119041 General transcription factor IIIC subunit 3 2 196763032-196799725 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA069179 Supported Nucleus
Nuclear membrane Liver cancer:1.26e-6 (unfavourable) Expressed in all Expressed in all gallbladder: 37.4 Expressed in all +SATB2 FLJ21474, KIAA1034 ENSG00000119042 SATB homeobox 2 2 199269500-199471266 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001042, CAB023669, HPA029543, CAB062562, CAB067751, CAB068229, CAB068230, CAB068231 Enhanced Supported Nucleoplasm Renal cancer:5.37e-8 (favourable) Tissue enhanced Group enriched 5 cerebral cortex: 22.7;colon: 34.1;rectum: 43.2 small intestine: 6.3 Mixed +UBE2B HHR6B, RAD6B, UBC2 ENSG00000119048 Ubiquitin conjugating enzyme E2 B 5 134371179-134391992 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003875, HPA051765, HPA065898 Supported Nucleoplasm
Vesicles
Plasma membrane
Cytosol Expressed in all Expressed in all adrenal gland: 99.1 Expressed in all +TRPM6 CHAK2, FLJ22628, HOMG, HSH ENSG00000119121 Transient receptor potential cation channel subfamily M member 6 9 74722495-74888094 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Tissue enhanced Tissue enhanced colon: 13.1;rectum: 18.2 small intestine: 8.7 Cell line enhanced BEWO: 3.7;HeLa: 1.5;RT4: 3.0 +GDA ENSG00000119125 Guanine deaminase 9 72114595-72257193 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019352, HPA024099, HPA030387 Enhanced Approved Nucleus Renal cancer:2.66e-5 (favourable) Mixed Tissue enhanced cerebral cortex: 102.2;duodenum: 95.2;small intestine: 104.1 kidney: 43.6 Cell line enhanced A-431: 31.0;EFO-21: 125.3;HeLa: 32.0;hTCEpi: 45.2 +KLF9 BTEB1 ENSG00000119138 Kruppel like factor 9 9 70384597-70414624 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029308 Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:6.59e-6 (favourable) Expressed in all Expressed in all smooth muscle: 88.4 Cell line enhanced ASC TERT1: 58.2;HHSteC: 90.2 +TJP2 DFNA51, X104, ZO-2, ZO2 ENSG00000119139 Tight junction protein 2 9 69121264-69255208 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001813, CAB009228, HPA070714 Supported Enhanced Nucleoplasm
Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.78e-14 (favourable) Expressed in all Expressed in all parathyroid gland: 104.1 Mixed +C2orf40 augurin, ECRG4 ENSG00000119147 Chromosome 2 open reading frame 40 2 106063246-106078159 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA008546 Uncertain Breast cancer:4.58e-4 (favourable) Tissue enriched Tissue enhanced seminal vesicle: 116.4;thyroid gland: 128.1 prostate: 61.6 Not detected +ITGB1BP1 ICAP-1A, ICAP-1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B ENSG00000119185 Integrin subunit beta 1 binding protein 1 2 9403475-9423547 Predicted intracellular proteins Evidence at protein level HPA067348, HPA071538 Supported Nucleoplasm
Nuclear bodies
Microtubule organizing center
Cytosol Endometrial cancer:1.03e-5 (unfavourable), Liver cancer:4.67e-5 (unfavourable), Renal cancer:7.10e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 125.4 Expressed in all +CPSF3 CPSF-73, CPSF73, YSH1 ENSG00000119203 Cleavage and polyadenylation specific factor 3 2 9423568-9473101 Predicted intracellular proteins Evidence at protein level HPA034657 Uncertain Liver cancer:3.64e-5 (unfavourable), Renal cancer:3.93e-5 (unfavourable) Expressed in all Expressed in all testis: 87.5 Expressed in all +PIGZ FLJ12768, MGC52163, SMP3 ENSG00000119227 Phosphatidylinositol glycan anchor biosynthesis class Z 3 196946343-196969060 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA058599, HPA059920 Approved Uncertain Vesicles Renal cancer:5.60e-5 (unfavourable) Expressed in all Tissue enhanced colon: 18.5;rectum: 18.1 cerebral cortex: 10.9 Mixed +SENP5 MGC27076 ENSG00000119231 SUMO1/sentrin specific peptidase 5 3 196867856-196934714 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:2.14e-5 (unfavourable), Endometrial cancer:4.04e-4 (unfavourable), Liver cancer:4.15e-4 (unfavourable) Expressed in all Expressed in all testis: 37.8 Expressed in all +CCDC92 FLJ22471 ENSG00000119242 Coiled-coil domain containing 92 12 123918660-123972831 Predicted intracellular proteins Evidence at protein level HPA038560, HPA057580 Approved Supported Nucleoplasm
Centrosome Pancreatic cancer:4.59e-5 (favourable), Endometrial cancer:7.15e-4 (favourable) Expressed in all Mixed testis: 18.1 Mixed +C1orf198 DKFZp667D152, FLJ14525, FLJ16283, FLJ38847, MGC10710 ENSG00000119280 Chromosome 1 open reading frame 198 1 230837119-230869589 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004798 Approved Supported Cytosol Renal cancer:4.50e-5 (unfavourable) Expressed in all Expressed in all lung: 99.2 Expressed in all +TRIM67 TNL ENSG00000119283 Tripartite motif containing 67 1 231162112-231221556 Predicted intracellular proteins Evidence at transcript level HPA034776 Uncertain Not detected Tissue enriched 28 cerebral cortex: 10.3 adrenal gland,testis: 0.3 Cell line enhanced SCLC-21H: 2.8 +HEATR1 BAP28, FLJ10359, UTP10 ENSG00000119285 HEAT repeat containing 1 1 236549005-236604504 Predicted intracellular proteins Evidence at protein level HPA046917, HPA062200 Approved Enhanced Nucleoli fibrillar center
Mitochondria Liver cancer:2.05e-4 (unfavourable), Renal cancer:4.04e-4 (unfavourable) Expressed in all Expressed in all testis: 27.0 Expressed in all +PTBP3 DKFZp781I1117, ROD1 ENSG00000119314 Polypyrimidine tract binding protein 3 9 112217716-112333667 Predicted intracellular proteins Evidence at protein level HPA048374 Approved Nucleus Pancreatic cancer:1.22e-4 (unfavourable), Lung cancer:2.10e-4 (unfavourable), Renal cancer:2.51e-4 (favourable) Expressed in all Expressed in all testis: 44.1 Expressed in all +RAD23B HHR23B, HR23B, P58 ENSG00000119318 RAD23 homolog B, nucleotide excision repair protein 9 107283137-107332194 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029718, HPA029720, CAB033868 Enhanced Supported Nucleoplasm
Cytosol Head and neck cancer:2.58e-4 (unfavourable), Lung cancer:6.71e-4 (unfavourable) Expressed in all Expressed in all placenta: 110.8 Expressed in all +FKBP15 FKBP133, KIAA0674, PPP1R76, WAFL ENSG00000119321 FK506 binding protein 15 9 113161006-113221361 Predicted intracellular proteins Evidence at protein level HPA007979 Approved Approved Nucleoli
Cytosol Testis cancer:4.92e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.0 Expressed in all +CTNNAL1 alpha-CATU, CLLP ENSG00000119326 Catenin alpha like 1 9 108942569-109013529 Predicted intracellular proteins Evidence at protein level Stomach cancer:3.77e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 263.0 Expressed in all +FAM206A C9orf6, CG-8, FLJ20457, Simiate ENSG00000119328 Family with sequence similarity 206 member A 9 108934181-108950744 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035917, HPA035918 Uncertain Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 36.8 Expressed in all +WDR34 bA216B9.3, DIC5, FAP133, MGC20486 ENSG00000119333 WD repeat domain 34 9 128633661-128656787 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040764, HPA041091 Approved Approved Cytosol Endometrial cancer:7.01e-5 (favourable), Cervical cancer:1.63e-4 (favourable), Liver cancer:8.79e-4 (unfavourable) Expressed in all Expressed in all testis: 53.0 Expressed in all +SET 2PP2A, IPP2A2, PHAPII ENSG00000119335 SET nuclear proto-oncogene 9 128683424-128696400 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005232, HPA063683 Supported Supported Nucleoplasm
Lipid droplets Liver cancer:9.41e-7 (unfavourable) Expressed in all Expressed in all lymph node: 361.2 Expressed in all +PTPA PPP2R4, PR53 ENSG00000119383 Protein phosphatase 2 phosphatase activator 9 129110950-129148946 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005695, CAB022068, CAB035999 Approved Enhanced Nucleoplasm
Cytosol Endometrial cancer:6.50e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 225.9 Expressed in all +GLE1 GLE1L, hGLE1, LCCS1 ENSG00000119392 GLE1, RNA export mediator 9 128504700-128542288 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA041689, HPA043538, HPA061560 Supported Supported Nuclear membrane
Nucleoli Stomach cancer:7.04e-4 (favourable), Endometrial cancer:7.49e-4 (favourable) Expressed in all Expressed in all testis: 58.8 Expressed in all +RAB14 FBP, RAB-14 ENSG00000119396 RAB14, member RAS oncogene family 9 121178137-121223014 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026419, CAB037066 Approved Supported Vesicles Renal cancer:1.79e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 83.4 Expressed in all +CNTRL CEP1, CEP110 ENSG00000119397 Centriolin 9 121074863-121177610 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020468, HPA020480, HPA051583 Approved Supported Centrosome
Cytosol Head and neck cancer:9.21e-5 (favourable) Expressed in all Tissue enhanced testis: 65.8 lymph node: 29.0 Expressed in all +TRIM32 BBS11, HT2A, LGMD2H, TATIP ENSG00000119401 Tripartite motif containing 32 9 116687302-116701300 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA050060 Approved Approved Intermediate filaments Head and neck cancer:4.53e-4 (unfavourable), Liver cancer:4.72e-4 (unfavourable) Expressed in all Mixed fallopian tube: 21.2 Mixed +FBXW2 FBW2, Fwd2, Md6 ENSG00000119402 F-box and WD repeat domain containing 2 9 120751978-120793412 Predicted intracellular proteins Evidence at protein level HPA067878 Approved Approved Nucleoplasm Renal cancer:1.38e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 42.6 Expressed in all +PHF19 DKFZP727G051, MTF2L1, PCL3, TDRD19B ENSG00000119403 PHD finger protein 19 9 120855652-120894896 Predicted intracellular proteins Evidence at protein level Renal cancer:1.16e-7 (unfavourable), Liver cancer:5.16e-5 (unfavourable), Endometrial cancer:7.60e-4 (unfavourable) Expressed in all Mixed lymph node: 49.5 Expressed in all +NEK6 SID6-1512 ENSG00000119408 NIMA related kinase 6 9 124257606-124353307 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level CAB045993, HPA056828 Approved Supported Nucleoplasm
Microtubule organizing center
Cytosol Testis cancer:7.66e-4 (unfavourable) Expressed in all Expressed in all appendix: 44.3 Cell line enhanced HMC-1: 219.5 +BSPRY FLJ20150 ENSG00000119411 B-box and SPRY domain containing 9 113349541-113371233 Predicted intracellular proteins Evidence at protein level HPA042889 Approved Approved Nucleoplasm
Cytosol Renal cancer:4.56e-14 (favourable) Mixed Tissue enriched 5 parathyroid gland: 254.8 thyroid gland: 50.4 Cell line enhanced A-431: 36.1;CAPAN-2: 22.7;MCF7: 46.9;RPMI-8226: 22.3;SK-BR-3: 22.3;T-47d: 28.3 +PPP6C PP6 ENSG00000119414 Protein phosphatase 6 catalytic subunit 9 125146573-125189939 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA050940 Uncertain Renal cancer:4.50e-6 (favourable) Expressed in all Expressed in all thyroid gland: 52.7 Expressed in all +NDUFA8 MGC793, PGIV ENSG00000119421 NADH:ubiquinone oxidoreductase subunit A8 9 122144058-122159819 Predicted intracellular proteins Evidence at protein level HPA041510, HPA041600 Enhanced Enhanced Mitochondria Renal cancer:4.17e-6 (favourable) Expressed in all Expressed in all heart muscle: 226.5 Expressed in all +HDHD3 C9orf158, MGC12904 ENSG00000119431 Haloacid dehalogenase like hydrolase domain containing 3 9 113373419-113376999 Predicted intracellular proteins Evidence at protein level HPA020427, HPA024158, HPA024585 Enhanced Supported Nucleoli Renal cancer:3.54e-7 (favourable), Cervical cancer:2.72e-4 (favourable) Expressed in all Expressed in all adrenal gland: 86.8 Mixed +RBM18 MGC2734 ENSG00000119446 RNA binding motif protein 18 9 122237624-122264839 Predicted intracellular proteins Evidence at protein level HPA057281 Uncertain Approved Nucleus
Nucleoli fibrillar center
Midbody Renal cancer:8.00e-7 (favourable) Expressed in all Expressed in all breast: 20.3 Expressed in all +SLC46A2 Ly110, TSCOT ENSG00000119457 Solute carrier family 46 member 2 9 112878920-112890913 Predicted membrane proteins, Transporters Evidence at transcript level HPA020098 Approved Tissue enhanced Group enriched 6 cervix, uterine: 23.3;endometrium: 5.5;epididymis: 5.7;lung: 15.1;skin: 11.3 seminal vesicle: 2.1 Not detected +HSDL2 C9orf99, SDR13C1 ENSG00000119471 Hydroxysteroid dehydrogenase like 2 9 112379937-112472410 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042890, HPA050453 Enhanced Supported Mitochondria Renal cancer:9.29e-7 (favourable), Endometrial cancer:9.23e-6 (favourable) Expressed in all Expressed in all adrenal gland: 79.2 Expressed in all +MAPKAP1 MGC2745, MIP1, SIN1 ENSG00000119487 Mitogen-activated protein kinase associated protein 1 9 125437393-125707234 Predicted intracellular proteins Evidence at protein level HPA029091, HPA029092 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:7.23e-6 (favourable) Expressed in all Expressed in all thyroid gland: 79.7 Expressed in all +NR4A3 CHN, CSMF, MINOR, NOR1 ENSG00000119508 Nuclear receptor subfamily 4 group A member 3 9 99821855-99866891 Cancer-related genes, Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043360 Uncertain Breast cancer:5.97e-4 (favourable) Mixed Tissue enhanced adrenal gland: 88.9 urinary bladder: 42.2 Cell line enhanced BJ hTERT+: 21.0;SK-MEL-30: 14.0;U-266/70: 7.9 +INVS NPHP2 ENSG00000119509 Inversin 9 100099256-100301000 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049994 Approved Cytosol Head and neck cancer:6.35e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 17.7 Expressed in all +GALNT12 GalNAc-T12 ENSG00000119514 Polypeptide N-acetylgalactosaminyltransferase 12 9 98807699-98850081 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA048292 Enhanced Renal cancer:3.24e-4 (favourable) Mixed Tissue enhanced epididymis: 92.1 rectum: 61.4 Cell line enhanced U-2197: 151.4 +DENND1A FAM31A, FLJ21129, KIAA1608 ENSG00000119522 DENN domain containing 1A 9 123379654-123930152 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020481 Supported Nucleoplasm
Vesicles
Cytosol Renal cancer:4.11e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 21.8 Expressed in all +ALG2 CDG1I, CDGIi, FLJ14511, hALPG2, NET38 ENSG00000119523 ALG2, alpha-1,3/1,6-mannosyltransferase 9 99216426-99221956 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041512, HPA041601 Approved Enhanced Actin filaments
Cytosol Renal cancer:2.28e-7 (favourable), Endometrial cancer:8.44e-5 (favourable), Head and neck cancer:1.56e-4 (unfavourable) Expressed in all Expressed in all epididymis: 77.1 Expressed in all +CSF3R CD114, GCSFR ENSG00000119535 Colony stimulating factor 3 receptor 1 36466043-36483278 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017116, HPA048086 Enhanced Testis cancer:3.79e-4 (unfavourable), Renal cancer:5.72e-4 (unfavourable) Mixed Tissue enhanced appendix: 211.2;bone marrow: 243.4;placenta: 147.9 spleen: 96.5 Cell line enhanced BEWO: 68.2;NB-4: 12.7;THP-1: 32.4;U-937: 36.3 +KDSR DHSR, FVT1, SDR35C1 ENSG00000119537 3-ketodihydrosphingosine reductase 18 63327726-63367510 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB003673, HPA044884 Approved Renal cancer:9.53e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 45.5 Expressed in all +VPS4B SKD1, SKD1B, VPS4-2 ENSG00000119541 Vacuolar protein sorting 4 homolog B 18 63389190-63422483 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040393, CAB046445, HPA057649 Approved Approved Vesicles
Intermediate filaments Renal cancer:1.23e-4 (favourable) Expressed in all Expressed in all esophagus: 82.7 Expressed in all +ONECUT2 OC-2 ENSG00000119547 One cut homeobox 2 18 57435685-57491297 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057058 Enhanced Supported Nucleoplasm
Actin filaments Group enriched Tissue enhanced duodenum: 10.4;gallbladder: 16.3 liver: 4.5 Cell line enhanced HDLM-2: 19.1;HeLa: 8.5;SCLC-21H: 12.1 +C19orf25 FLJ36666 ENSG00000119559 Chromosome 19 open reading frame 25 19 1461143-1479556 Predicted intracellular proteins Evidence at protein level HPA050270, HPA067491 Approved Approved Intermediate filaments Renal cancer:9.20e-8 (favourable), Endometrial cancer:1.08e-4 (favourable), Pancreatic cancer:1.21e-4 (favourable), Liver cancer:3.81e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 21.7 Expressed in all +ZBTB45 FLJ14486, ZNF499 ENSG00000119574 Zinc finger and BTB domain containing 45 19 58513530-58538911 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA035754 Uncertain Approved Cytosol Renal cancer:5.38e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 10.5 Expressed in all +YLPM1 C14orf170, PPP1R169, ZAP ENSG00000119596 YLP motif containing 1 14 74763366-74859435 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048070, HPA061123 Uncertain Supported Nucleoplasm
Nuclear speckles Renal cancer:6.08e-7 (favourable) Expressed in all Expressed in all testis: 39.1 Expressed in all +DCAF4 DKFZp434K114, WDR21, WDR21A ENSG00000119599 DDB1 and CUL4 associated factor 4 14 72926332-72959703 Predicted intracellular proteins Evidence at protein level HPA047276 Approved Approved Nucleoplasm Renal cancer:4.90e-4 (favourable), Liver cancer:6.77e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 18.8 Expressed in all +PROX2 FLJ36749 ENSG00000119608 Prospero homeobox 2 14 74852871-74871940 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045057 Uncertain Not detected Mixed skin: 2.4 Cell line enhanced AF22: 1.8 +VSX2 CHX10, HOX10, RET1 ENSG00000119614 Visual system homeobox 2 14 74239472-74262738 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003436 Supported Tissue enriched Not detected testis: 0.2 Not detected +FCF1 Bka, C14orf111, CGI-35, UTP24 ENSG00000119616 FCF1 rRNA-processing protein 14 74713144-74738620 Predicted intracellular proteins Evidence at protein level HPA046681 Approved Approved Nucleoplasm Liver cancer:5.54e-6 (unfavourable), Renal cancer:2.26e-4 (favourable), Pancreatic cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 72.6 Expressed in all +PGF D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760 ENSG00000119630 Placental growth factor 14 74941834-74955784 Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA041624 Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:1.33e-6 (unfavourable), Liver cancer:1.40e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 71.1;thyroid gland: 64.5 cervix, uterine: 30.1 Group enriched 6 BEWO: 398.0;HUVEC TERT2: 164.7 +IFI27L2 FAM14A, TLH29 ENSG00000119632 Interferon alpha inducible protein 27 like 2 14 94127779-94130253 Predicted secreted proteins Evidence at protein level HPA049588 Approved Nucleoli
Cytosol Expressed in all Expressed in all adrenal gland: 47.5 Cell line enhanced Karpas-707: 135.5 +BBOF1 C14orf45, CCDC176 ENSG00000119636 Basal body orientation factor 1 14 74019353-74082863 Predicted intracellular proteins Evidence at protein level HPA003090, HPA003136 Uncertain Approved Nucleus
Plasma membrane
Microtubule organizing center Endometrial cancer:6.34e-4 (favourable) Expressed in all Tissue enhanced testis: 70.0 fallopian tube: 35.8 Mixed +NEK9 DKFZp434D0935, MGC16714, Nek8, NERCC ENSG00000119638 NIMA related kinase 9 14 75079353-75127344 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA001405 Approved Approved Mitochondria Pancreatic cancer:5.63e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 29.9 Mixed +ACYP1 ENSG00000119640 Acylphosphatase 1 14 75053221-75069483 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA034944 Approved Approved Nucleus
Cytosol Liver cancer:6.14e-7 (unfavourable), Breast cancer:1.17e-4 (favourable) Expressed in all Expressed in all adrenal gland: 46.4 Expressed in all +IFT43 C14orf179, FLJ32173, MGC16028 ENSG00000119650 Intraflagellar transport 43 14 75902136-76084585 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003438 Approved Supported Microtubules
Microtubule organizing center Expressed in all Expressed in all fallopian tube: 99.1 Mixed +NPC2 EDDM1, HE1, NP-C2 ENSG00000119655 NPC intracellular cholesterol transporter 2 14 74476192-74494177 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA000835 Enhanced Colorectal cancer:4.83e-5 (unfavourable), Stomach cancer:2.66e-4 (unfavourable), Liver cancer:3.13e-4 (unfavourable), Thyroid cancer:6.55e-4 (favourable) Expressed in all Tissue enriched 19 epididymis: 16336.0 lung: 849.0 Expressed in all +DNAL1 1700010H15RiK, C14orf168, CILD16, MGC12435 ENSG00000119661 Dynein axonemal light chain 1 14 73644875-73703732 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053129 Uncertain Approved Nucleus
Microtubule organizing center Renal cancer:5.17e-8 (favourable) Expressed in all Expressed in all testis: 99.4 Expressed in all +IRF2BPL C14orf4, EAP1, KIAA1865 ENSG00000119669 Interferon regulatory factor 2 binding protein like 14 77024543-77028699 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050862, HPA061333 Approved Enhanced Nucleoplasm Endometrial cancer:5.52e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.5 Expressed in all +ACOT2 Mte1, ZAP128 ENSG00000119673 Acyl-CoA thioesterase 2 14 73567620-73575658 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043705, HPA060170 Enhanced Approved Mitochondria Renal cancer:2.28e-6 (favourable) Expressed in all Expressed in all adipose tissue: 96.5 Mixed +LTBP2 C14orf141, LTBP3 ENSG00000119681 Latent transforming growth factor beta binding protein 2 14 74498170-74612378 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003415 Approved Approved Nucleus Urothelial cancer:3.94e-4 (unfavourable) Expressed in all Mixed lung: 75.1 Cell line enhanced fHDF/TERT166: 185.0;TIME: 465.3 +AREL1 FIEL1, KIAA0317 ENSG00000119682 Apoptosis resistant E3 ubiquitin protein ligase 1 14 74653437-74713115 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051306 Uncertain Renal cancer:4.67e-6 (favourable) Expressed in all Expressed in all testis: 33.8 Expressed in all +MLH3 ENSG00000119684 MutL homolog 3 14 75013764-75051532 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060570 Approved Nucleus Expressed in all Expressed in all parathyroid gland: 24.4 Mixed +TTLL5 KIAA0998 ENSG00000119685 Tubulin tyrosine ligase like 5 14 75633625-75955078 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA032128 Uncertain Supported Plasma membrane
Cytosol Expressed in all Tissue enriched 5 testis: 104.0 parathyroid gland: 20.4 Expressed in all +FLVCR2 C14orf58, FLJ20371, MFSD7C ENSG00000119686 Feline leukemia virus subgroup C cellular receptor family member 2 14 75578617-75663214 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA037984 Enhanced Renal cancer:2.53e-5 (favourable) Expressed in all Tissue enhanced testis: 38.8 small intestine: 26.9 Cell line enhanced ASC diff: 37.0;BEWO: 71.0 +ABCD4 EST352188, P70R, PMP69, PXMP1L ENSG00000119688 ATP binding cassette subfamily D member 4 14 74285423-74303056 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA003396 Approved Expressed in all Expressed in all fallopian tube: 13.8 Expressed in all +DLST DLTS ENSG00000119689 Dihydrolipoamide S-succinyltransferase 14 74881891-74903745 Citric acid cycle related proteins, Enzymes, Predicted intracellular proteins Evidence at protein level HPA003010 Supported Renal cancer:1.13e-12 (favourable) Expressed in all Expressed in all kidney: 106.7 Expressed in all +PPP4R4 CFAP14, KIAA1622, PP4R4 ENSG00000119698 Protein phosphatase 4 regulatory subunit 4 14 94146128-94279735 Predicted intracellular proteins Evidence at protein level HPA041866, HPA050321 Approved Supported Cytosol Mixed Tissue enhanced cerebral cortex: 14.0;testis: 11.1 ovary: 5.4 Cell line enhanced RH-30: 17.0;T-47d: 17.6 +TGFB3 ARVD, ARVD1 ENSG00000119699 Transforming growth factor beta 3 14 75958099-75982991 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level HPA063582 Approved Vesicles Renal cancer:4.01e-7 (unfavourable) Expressed in all Mixed placenta: 84.9 Group enriched 5 SCLC-21H: 28.0;SK-BR-3: 99.2;T-47d: 87.5 +ZC2HC1C C14orf140, FAM164C ENSG00000119703 Zinc finger C2HC-type containing 1C 14 75064170-75079987 Predicted intracellular proteins Evidence at protein level HPA050928, HPA065062 Enhanced Approved Nuclear speckles
Mitochondria Renal cancer:4.63e-13 (favourable) Mixed Tissue enhanced testis: 118.3 epididymis: 34.2 Mixed +SLIRP C14orf156, DC50 ENSG00000119705 SRA stem-loop interacting RNA binding protein 14 77708071-77761104 Predicted intracellular proteins Evidence at protein level HPA020291 Approved Supported Mitochondria Head and neck cancer:4.88e-4 (unfavourable) Expressed in all Expressed in all epididymis: 205.7 Expressed in all +RBM25 fSAP94, NET52, RNPC7, S164, Snu71 ENSG00000119707 RNA binding motif protein 25 14 73058436-73123898 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003025, HPA070713 Supported Enhanced Nuclear speckles Liver cancer:1.42e-4 (unfavourable), Renal cancer:4.26e-4 (unfavourable), Prostate cancer:8.09e-4 (unfavourable) Expressed in all Expressed in all testis: 53.4 Expressed in all +ALDH6A1 MMSDH ENSG00000119711 Aldehyde dehydrogenase 6 family member A1 14 74056850-74084493 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029072, HPA029073, HPA029074, HPA029075 Enhanced Enhanced Mitochondria Renal cancer:2.00e-15 (favourable), Lung cancer:4.22e-4 (favourable) Expressed in all Expressed in all kidney: 389.6 Expressed in all +GPR68 OGR1 ENSG00000119714 G protein-coupled receptor 68 14 91232532-91253925 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Endometrial cancer:3.06e-5 (favourable) Mixed Mixed appendix: 8.1 Cell line enhanced U-87 MG: 31.4 +ESRRB DFNB35, ERR2, ERRb, ERRbeta, ESRL2, NR3B2 ENSG00000119715 Estrogen related receptor beta 14 76310614-76501841 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Group enriched 7 heart muscle: 2.3;kidney: 5.2;skeletal muscle: 1.7;stomach: 1.5;testis: 1.4 breast: 0.3 Cell line enhanced HMC-1: 1.0;K-562: 3.3;U-266/70: 1.2 +EIF2B2 EIF-2Bbeta, EIF2B ENSG00000119718 Eukaryotic translation initiation factor 2B subunit beta 14 75002911-75012366 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005841, CAB037105, HPA048028 Enhanced Approved Nucleoplasm
Plasma membrane
Focal adhesion sites Liver cancer:2.26e-6 (unfavourable), Renal cancer:2.95e-4 (favourable) Expressed in all Mixed thyroid gland: 19.2 Expressed in all +NRDE2 C14orf102, FLJ14051 ENSG00000119720 NRDE-2, necessary for RNA interference, domain containing 14 90267856-90332137 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047050, HPA050583 Uncertain Supported Nucleoplasm
Mitochondria Expressed in all Mixed parathyroid gland: 2.9 Mixed +COQ6 CGI-10 ENSG00000119723 Coenzyme Q6, monooxygenase 14 73949926-73963670 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051371 Uncertain Renal cancer:1.05e-6 (favourable) Expressed in all Expressed in all testis: 31.5 Expressed in all +ZNF410 APA-1, APA1 ENSG00000119725 Zinc finger protein 410 14 73886617-73932511 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002871 Approved Nuclear bodies Mixed Expressed in all testis: 81.3 Expressed in all +RHOQ ARHQ, RASL7A, TC10 ENSG00000119729 Ras homolog family member Q 2 46541806-46583121 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044938 Approved Vesicles
Cytosol Liver cancer:9.60e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 167.5 Expressed in all +GPR75 WI-31133 ENSG00000119737 G protein-coupled receptor 75 2 53852913-53859989 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 17.8 parathyroid gland: 6.5 Mixed +SUPT7L KIAA0764, SPT7L, STAF65, STAF65gamma ENSG00000119760 SPT7-like STAGA complex gamma subunit 2 27650812-27663840 Predicted intracellular proteins Evidence at protein level HPA039565, HPA063643 Uncertain Approved Nucleoplasm Liver cancer:4.46e-7 (unfavourable), Renal cancer:1.53e-4 (unfavourable), Endometrial cancer:2.28e-4 (unfavourable) Expressed in all Expressed in all endometrium: 45.6 Expressed in all +KLHL29 KBTBD9, KIAA1921 ENSG00000119771 Kelch like family member 29 2 23385217-23708611 Predicted intracellular proteins Evidence at protein level HPA049057, HPA057379 Approved Approved Mitochondria
Cytosol Pancreatic cancer:2.19e-4 (favourable), Renal cancer:6.29e-4 (unfavourable) Mixed Mixed adrenal gland: 12.0 Cell line enhanced RH-30: 18.8 +DNMT3A ENSG00000119772 DNA methyltransferase 3 alpha 2 25227855-25342590 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009469, HPA026588 Approved Supported Nucleoplasm Pancreatic cancer:1.18e-4 (favourable), Endometrial cancer:1.55e-4 (unfavourable), Liver cancer:1.58e-4 (unfavourable), Renal cancer:2.49e-4 (unfavourable) Expressed in all Expressed in all placenta: 22.8 Cell line enhanced NTERA-2: 59.7;SH-SY5Y: 76.5 +TMEM214 FLJ20254 ENSG00000119777 Transmembrane protein 214 2 27032910-27041695 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034551 Supported Endoplasmic reticulum
Golgi apparatus
Cytosol Renal cancer:2.39e-10 (unfavourable), Liver cancer:4.96e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 91.6 Expressed in all +ATAD2B KIAA1240 ENSG00000119778 ATPase family, AAA domain containing 2B 2 23748664-23927114 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034555 Uncertain Supported Nucleoplasm Renal cancer:2.35e-5 (unfavourable) Expressed in all Mixed skin: 9.8 Expressed in all +FKBP1B FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase ENSG00000119782 FK506 binding protein 1B 2 24049701-24063681 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045572, HPA051798 Uncertain Approved Vesicles Expressed in all Tissue enhanced cerebral cortex: 24.4 duodenum: 18.6 Cell line enhanced Hep G2: 30.2;NTERA-2: 41.7;SH-SY5Y: 31.9;TIME: 30.3 +ATL2 ARL6IP2 ENSG00000119787 Atlastin GTPase 2 2 38294880-38377285 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029108, HPA075302 Approved Supported Endoplasmic reticulum Endometrial cancer:4.51e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 101.4 Expressed in all +YPEL5 CGI-127 ENSG00000119801 Yippee like 5 2 30146941-30160533 Predicted intracellular proteins Evidence at protein level HPA042809 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all bone marrow: 271.5 Expressed in all +FAM98A DKFZP564F0522 ENSG00000119812 Family with sequence similarity 98 member A 2 33583658-33599382 Predicted intracellular proteins Evidence at protein level HPA036250, HPA036251 Uncertain Supported Vesicles Liver cancer:4.86e-7 (unfavourable), Thyroid cancer:8.18e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 127.4 Expressed in all +YIPF4 FinGER4, MGC11061 ENSG00000119820 Yip1 domain family member 4 2 32277910-32316594 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017884 Supported Supported Golgi apparatus
Vesicles
Plasma membrane Expressed in all Expressed in all cerebral cortex: 19.0 Expressed in all +AFTPH FLJ20080, FLJ23793, MGC33965, Nbla10388 ENSG00000119844 Aftiphilin 2 64524305-64593005 Predicted intracellular proteins Evidence at protein level HPA034990, HPA034991 Approved Supported Golgi apparatus
Vesicles
Cytosol Renal cancer:2.37e-5 (favourable), Urothelial cancer:1.83e-4 (favourable), Stomach cancer:8.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 65.7 Expressed in all +LGALSL GRP, HSPC159 ENSG00000119862 Galectin like 2 64453969-64461381 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046079 Approved Approved Nucleoplasm Liver cancer:2.16e-4 (unfavourable) Expressed in all Expressed in all skin: 110.9 Cell line enhanced AN3-CA: 46.2;HAP1: 75.2 +CNRIP1 C2orf32, CRIP1, CRIP1a, CRIP1b, DKFZP566K1924 ENSG00000119865 Cannabinoid receptor interacting protein 1 2 68284171-68320051 Predicted intracellular proteins Evidence at protein level HPA035337 Approved Cytosol Renal cancer:1.21e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 53.8 adipose tissue: 24.9 Cell line enhanced HEL: 139.6 +BCL11A BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, ZNF856 ENSG00000119866 B-cell CLL/lymphoma 11A 2 60451167-60553567 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB014891, HPA029003 Enhanced Enhanced Nucleoplasm
Nuclear bodies Mixed Tissue enhanced skin: 41.0 tonsil: 30.6 Cell line enhanced Daudi: 24.7;MOLT-4: 28.5;REH: 32.5;U-698: 43.2 +CRIPT HSPC139 ENSG00000119878 CXXC repeat containing interactor of PDZ3 domain 2 46616416-46625742 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046080, HPA056765 Approved Supported Nucleus
Nucleoli Liver cancer:1.19e-4 (unfavourable), Renal cancer:5.54e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 25.5 Expressed in all +EPCAM 17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1 ENSG00000119888 Epithelial cell adhesion molecule 2 47345158-47387601 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB003809, HPA026761, CAB030012, CAB055098, HPA067463 Enhanced Supported Plasma membrane Renal cancer:1.04e-6 (favourable), Ovarian cancer:3.30e-4 (favourable) Mixed Tissue enhanced rectum: 680.5;small intestine: 714.7 colon: 659.9 Cell line enhanced A-431: 382.2;CACO-2: 461.4;CAPAN-2: 680.1;SCLC-21H: 345.3 +SLC17A5 AST, ISSD, NSD, SD, SIALIN, SIASD, SLD ENSG00000119899 Solute carrier family 17 member 5 6 73593379-73654155 Disease related genes, Predicted membrane proteins Evidence at protein level HPA044479 Supported Plasma membrane
Cytosol Thyroid cancer:3.52e-4 (favourable) Expressed in all Tissue enriched 9 parathyroid gland: 652.6 thyroid gland: 70.0 Expressed in all +OGFRL1 dJ331H24.1 ENSG00000119900 Opioid growth factor receptor like 1 6 71288803-71308950 Predicted intracellular proteins Evidence at protein level HPA027122 Approved Nucleoplasm
Golgi apparatus Liver cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 70.3 Mixed +SLF2 C10orf6, FAM178A, FLJ10512, FLJ25012 ENSG00000119906 SMC5-SMC6 complex localization factor 2 10 100912569-100965136 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038499, HPA057568 Approved Supported Nucleus
Vesicles Expressed in all Expressed in all epididymis: 56.9 Expressed in all +IDE ENSG00000119912 Insulin degrading enzyme 10 92451684-92574076 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA063478 Approved Endometrial cancer:3.53e-4 (favourable), Colorectal cancer:3.69e-4 (favourable) Expressed in all Expressed in all skin: 63.4 Expressed in all +TECTB ENSG00000119913 Tectorin beta 10 112283735-112305035 Predicted membrane proteins Evidence at transcript level Not detected Not detected epididymis: 0.6 Cell line enhanced Hep G2: 1.7 +ELOVL3 CIG-30 ENSG00000119915 ELOVL fatty acid elongase 3 10 102226328-102229589 Enzymes, Predicted membrane proteins Evidence at protein level HPA036236 Supported Approved Vesicles
Cytosol Endometrial cancer:6.25e-5 (unfavourable) Tissue enhanced Tissue enhanced adipose tissue: 3.6;breast: 4.4;skin: 3.4 testis: 2.3 Cell line enhanced HSkMC: 10.4;SiHa: 24.5 +IFIT3 CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, RIG-G ENSG00000119917 Interferon induced protein with tetratricopeptide repeats 3 10 89327894-89340971 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059914 Approved Supported Mitochondria
Cytosol Renal cancer:3.17e-4 (unfavourable) Expressed in all Expressed in all lung: 63.4 Group enriched 5 BJ hTERT+: 159.3;BJ hTERT+ SV40 Large T+: 419.8;BJ hTERT+ SV40 Large T+ RasG12V: 506.2 +NKX2-3 CSX3, NKX2.3, NKX2C, NKX4-3 ENSG00000119919 NK2 homeobox 3 10 99532933-99536524 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047561 Uncertain Uncertain Nucleoli
Cytosol Tissue enhanced Tissue enhanced small intestine: 12.7;spleen: 29.6 duodenum: 11.5 Cell line enhanced NB-4: 1.1;REH: 2.0 +IFIT2 cig42, G10P2, GARG-39, IFI-54, IFI54, ISG-54K ENSG00000119922 Interferon induced protein with tetratricopeptide repeats 2 10 89283694-89309276 Predicted intracellular proteins Evidence at protein level HPA003408 Approved Approved Vesicles Renal cancer:6.99e-4 (unfavourable) Expressed in all Mixed spleen: 39.1 Cell line enhanced BJ hTERT+ SV40 Large T+: 132.1;BJ hTERT+ SV40 Large T+ RasG12V: 108.9 +GPAM GPAT1, KIAA1560, MGC26846 ENSG00000119927 Glycerol-3-phosphate acyltransferase, mitochondrial 10 112149864-112215377 Enzymes, Predicted membrane proteins Evidence at protein level HPA046339, HPA060090 Approved Approved Mitochondria Renal cancer:4.54e-6 (favourable) Tissue enriched Expressed in all adipose tissue: 315.8 Expressed in all +CUTC CGI-32 ENSG00000119929 CutC copper transporter 10 99702558-99756134 Predicted intracellular proteins, Transporters Evidence at protein level HPA038619 Approved Supported Nucleoplasm
Cytosol Renal cancer:3.81e-7 (unfavourable) Expressed in all Expressed in all skeletal muscle: 131.6 Expressed in all +PPP1R3C PPP1R5, PTG ENSG00000119938 Protein phosphatase 1 regulatory subunit 3C 10 91628442-91633054 Predicted intracellular proteins Evidence at protein level HPA027041 Uncertain Expressed in all Tissue enhanced skeletal muscle: 322.7 heart muscle: 111.2 Cell line enhanced HHSteC: 43.7;LHCN-M2: 86.1 +PYROXD2 C10orf33, FLJ23849 ENSG00000119943 Pyridine nucleotide-disulphide oxidoreductase domain 2 10 98383565-98415184 Predicted intracellular proteins Evidence at protein level HPA037566, HPA037567, HPA067394 Uncertain Approved Mitochondria Urothelial cancer:3.37e-4 (favourable), Glioma:8.17e-4 (unfavourable) Expressed in all Mixed fallopian tube: 15.4 Cell line enhanced U-937: 24.6 +CNNM1 ACDP1 ENSG00000119946 Cyclin and CBS domain divalent metal cation transport mediator 1 10 99329099-99394330 Predicted membrane proteins Evidence at protein level HPA040408 Approved Uncertain Plasma membrane
Cytosol Mixed Tissue enhanced cerebral cortex: 10.2;testis: 16.8 ovary: 3.0 Cell line enhanced A549: 16.9;BJ hTERT+ SV40 Large T+ RasG12V: 10.6;HAP1: 8.6 +MXI1 bHLHc11, MAD2, MXD2, MXI ENSG00000119950 MAX interactor 1, dimerization protein 10 110207605-110287365 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035319, HPA056762 Approved Supported Nucleus
Nucleoli Renal cancer:1.02e-5 (unfavourable), Prostate cancer:9.17e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 88.1 Expressed in all +SMNDC1 SMNR, SPF30, TDRD16C ENSG00000119953 Survival motor neuron domain containing 1 10 110290730-110304951 Predicted intracellular proteins Evidence at protein level HPA061214 Supported Nucleus
Nuclear bodies Liver cancer:8.08e-6 (unfavourable), Pancreatic cancer:7.20e-4 (unfavourable) Expressed in all Expressed in all placenta: 26.3 Expressed in all +C10orf88 Em:AC073585.5, FLJ13490 ENSG00000119965 Chromosome 10 open reading frame 88 10 122930903-122954403 Predicted intracellular proteins Evidence at protein level HPA039681, HPA040991 Enhanced Liver cancer:2.05e-5 (unfavourable) Expressed in all Mixed testis: 14.3 Expressed in all +HELLS LSH, Nbla10143, PASG, SMARCA6 ENSG00000119969 Helicase, lymphoid-specific 10 94501434-94613905 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004491, HPA063242 Enhanced Approved Nucleus
Golgi apparatus
Vesicles Cervical cancer:1.36e-4 (favourable) Expressed in all Tissue enhanced testis: 23.9 lymph node: 14.9 Expressed in all +PRLHR GPR10, PrRPR ENSG00000119973 Prolactin releasing hormone receptor 10 118589989-118595699 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA039361 Supported Not detected Group enriched 6 adrenal gland: 6.7;cerebral cortex: 3.7;endometrium: 4.0;smooth muscle: 5.5 seminal vesicle: 0.7 Not detected +TCTN3 C10orf61, DKFZP564D116, JBTS18, TECT3 ENSG00000119977 Tectonic family member 3 10 95663396-95694143 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026987 Approved Approved Microtubules Endometrial cancer:5.77e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 138.1 Expressed in all +FAM45A ENSG00000119979 Family with sequence similarity 45 member A 10 119104086-119137984 Predicted intracellular proteins Evidence at protein level HPA041159 Approved Plasma membrane
Centrosome
Cytosol Expressed in all Expressed in all thyroid gland: 21.0 Expressed in all +AVPI1 PP5395, VIP32, VIT32 ENSG00000119986 Arginine vasopressin induced 1 10 97677424-97687323 Predicted intracellular proteins Evidence at protein level HPA037649 Approved Approved Nucleus
Plasma membrane Expressed in all Mixed adrenal gland: 42.1 Cell line enhanced hTCEpi: 154.8;SK-MEL-30: 138.8;U-2197: 116.9 +WDR11 BRWD2, DR11, FLJ10506, HH14, KIAA1351, SRI1, WDR15 ENSG00000120008 WD repeat domain 11 10 120851175-120909524 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038980 Approved Approved Microtubules
Cytosol Renal cancer:5.04e-4 (favourable) Expressed in all Mixed parathyroid gland: 46.6 Expressed in all +C10orf76 FLJ13114 ENSG00000120029 Chromosome 10 open reading frame 76 10 101845599-102056193 Predicted intracellular proteins Evidence at protein level HPA050913, HPA053580 Approved Approved Vesicles Expressed in all Expressed in all parathyroid gland: 26.4 Mixed +KCNIP2 KCHIP2 ENSG00000120049 Potassium voltage-gated channel interacting protein 2 10 101825974-101843920 Predicted intracellular proteins Evidence at protein level Mixed Group enriched 9 adipose tissue: 238.6;cerebral cortex: 81.4;heart muscle: 108.2 breast: 16.6 Cell line enhanced HEL: 13.8;HMC-1: 9.2 +CFAP58 bA554P13.1, C10orf80, CCDC147, FLJ35908 ENSG00000120051 Cilia and flagella associated protein 58 10 104353764-104455090 Predicted intracellular proteins Evidence at protein level HPA036555, HPA036556 Uncertain Approved Nucleus Mixed Group enriched 5 fallopian tube: 13.3;testis: 23.5 cervix, uterine: 3.3 Cell line enhanced U-2 OS: 6.5 +GOT1 AST1 ENSG00000120053 Glutamic-oxaloacetic transaminase 1 10 99396870-99430624 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064532, HPA072629 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:3.72e-13 (favourable), Cervical cancer:6.23e-4 (favourable) Expressed in all Expressed in all heart muscle: 321.5 Expressed in all +CPN1 ENSG00000120054 Carboxypeptidase N subunit 1 10 100042193-100081877 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040323 Approved Nucleus
Nucleoli Group enriched Tissue enriched 22 liver: 37.1 testis: 1.7 Cell line enriched 16 SK-MEL-30: 110.4 +C10orf95 FLJ14280 ENSG00000120055 Chromosome 10 open reading frame 95 10 102449837-102451543 Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced fallopian tube: 15.6 thyroid gland: 8.8 Mixed +SFRP5 SARP3 ENSG00000120057 Secreted frizzled related protein 5 10 97766751-97771952 Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced duodenum: 30.9;pancreas: 31.2;small intestine: 29.4 adrenal gland: 12.9 Cell line enhanced A549: 2.3;CACO-2: 10.5;RPMI-8226: 3.2;SCLC-21H: 2.4 +GNA13 G13, MGC46138 ENSG00000120063 G protein subunit alpha 13 17 65010715-65056839 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA010087 Approved Supported Cytosol Expressed in all Expressed in all bone marrow: 99.1 Expressed in all +HOXB8 HOX2, HOX2D ENSG00000120068 Homeobox B8 17 48611377-48614939 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA075905 Supported Nucleoplasm Renal cancer:1.30e-7 (favourable) Tissue enhanced Tissue enhanced epididymis: 68.0;seminal vesicle: 32.7 cervix, uterine: 16.9 Cell line enhanced EFO-21: 33.5;HDLM-2: 15.7;HEK 293: 34.4;LHCN-M2: 15.9;RPTEC TERT1: 29.7 +KANSL1 CENP-36, DKFZP727C091, KIAA1267, MSL1v1, NSL1 ENSG00000120071 KAT8 regulatory NSL complex subunit 1 17 46029916-46225389 Predicted intracellular proteins Evidence at protein level HPA006874, HPA007208 Approved Supported Nucleoplasm Liver cancer:3.74e-4 (unfavourable) Expressed in all Expressed in all testis: 32.4 Mixed +HOXB5 HOX2, HOX2A ENSG00000120075 Homeobox B5 17 48591257-48593961 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043851, HPA074454 Enhanced Nucleus Urothelial cancer:8.59e-5 (favourable), Lung cancer:4.61e-4 (unfavourable), Endometrial cancer:6.28e-4 (favourable) Tissue enhanced Tissue enhanced epididymis: 20.2 fallopian tube: 10.7 Cell line enhanced HEK 293: 24.1;RPTEC TERT1: 14.7 +CRHR1 CRF-R, CRF1, CRHR ENSG00000120088 Corticotropin releasing hormone receptor 1 17 45784280-45835828 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB025251 Approved Mixed Tissue enhanced cerebral cortex: 4.0 endometrium: 0.8 Cell line enhanced RT4: 2.7;SH-SY5Y: 2.2 +HOXB3 HOX2, HOX2G ENSG00000120093 Homeobox B3 17 48548870-48604912 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009860 Approved Urothelial cancer:8.45e-6 (favourable) Mixed Tissue enhanced epididymis: 79.4 fallopian tube: 38.7 Cell line enhanced CAPAN-2: 35.1;HEK 293: 38.6 +HOXB1 HOX2, HOX2I ENSG00000120094 Homeobox B1 17 48528526-48530997 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044576 Uncertain Tissue enriched Not detected testis: 0.3 Not detected +DUSP1 CL100, HVH1, MKP-1, PTPN10 ENSG00000120129 Dual specificity phosphatase 1 5 172768090-172771195 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB018554, HPA069577 Approved Approved Nucleoli
Cytosol Stomach cancer:3.11e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 1027.0 Expressed in all +PANK3 FLJ12899 ENSG00000120137 Pantothenate kinase 3 5 168548495-168579600 Enzymes, Predicted intracellular proteins Evidence at protein level HPA062358 Approved Nucleoplasm
Golgi apparatus Colorectal cancer:3.94e-4 (favourable) Expressed in all Expressed in all duodenum: 40.8 Expressed in all +MSX2 CRS2, FPP, HOX8, MSH, PFM, PFM1 ENSG00000120149 Msh homeobox 2 5 174724533-174730893 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005652 Uncertain Supported Nuclear speckles Endometrial cancer:8.43e-5 (favourable), Lung cancer:6.93e-4 (unfavourable) Mixed Tissue enhanced placenta: 47.8 parathyroid gland: 16.4 Cell line enriched 7 BEWO: 311.1 +TEK CD202b, TIE-2, TIE2, VMCM, VMCM1 ENSG00000120156 TEK receptor tyrosine kinase 9 27109141-27230175 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB010359, HPA073265 Approved Supported Plasma membrane
Microtubule organizing center Liver cancer:2.31e-5 (favourable), Renal cancer:7.81e-4 (favourable) Expressed in all Tissue enhanced placenta: 65.9 lung: 42.6 Group enriched 8 HUVEC TERT2: 74.6;NTERA-2: 44.2;TIME: 80.0 +RCL1 RNAC, RPCL1 ENSG00000120158 RNA terminal phosphate cyclase like 1 9 4792869-4885917 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA071308 Approved Nucleoplasm Renal cancer:2.40e-7 (favourable), Breast cancer:5.48e-4 (favourable), Liver cancer:8.02e-4 (favourable) Expressed in all Expressed in all liver: 123.7 Expressed in all +CAAP1 C9orf82, CAAP, FLJ13657 ENSG00000120159 Caspase activity and apoptosis inhibitor 1 9 26840685-26892804 Predicted intracellular proteins Evidence at protein level HPA020404, HPA024029, HPA024100 Uncertain Approved Vesicles Renal cancer:7.94e-9 (favourable), Ovarian cancer:1.27e-5 (favourable) Expressed in all Expressed in all thyroid gland: 49.6 Mixed +EQTN AFAF, C9orf11, equatorin, SPACA8 ENSG00000120160 Equatorin 9 27284659-27297139 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015089, HPA015504 Enhanced Not detected Tissue enriched 94 testis: 67.7 ovary: 0.7 Not detected +MOB3B C9orf35, FLJ13204, MOB1D, MOBKL2B ENSG00000120162 MOB kinase activator 3B 9 27325209-27529781 Predicted intracellular proteins Evidence at protein level HPA057744 Uncertain Intermediate filaments
Cytosol Renal cancer:2.33e-10 (favourable), Thyroid cancer:1.02e-4 (unfavourable) Expressed in all Mixed ovary: 32.0 Cell line enhanced HAP1: 17.3;K-562: 44.7 +INSL6 RIF1 ENSG00000120210 Insulin like 6 9 5131979-5185668 Predicted secreted proteins Evidence at protein level HPA021364 Enhanced Not detected Tissue enriched 40 testis: 21.6 placenta: 0.5 Not detected +INSL4 EPIL ENSG00000120211 Insulin like 4 9 5231419-5235304 Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 12 placenta: 22.2 epididymis: 1.8 Cell line enriched 10 A549: 22.2 +MLANA MART1 ENSG00000120215 Melan-A 9 5890802-5910606 Predicted membrane proteins Evidence at protein level CAB000057, HPA048662 Enhanced Tissue enriched Tissue enriched 25 skin: 50.4 breast: 1.9 Cell line enriched 330 SK-MEL-30: 523.2 +CD274 B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1 ENSG00000120217 CD274 molecule 9 5450503-5470566 Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB030018, CAB076385 Enhanced Approved Cytosol Colorectal cancer:1.64e-5 (favourable), Breast cancer:8.89e-4 (favourable) Mixed Mixed appendix: 14.0 Cell line enhanced HDLM-2: 82.8;HHSteC: 46.6;U-251 MG: 80.8 +IFNA6 IFN-alphaK ENSG00000120235 Interferon alpha 6 9 21349835-21351378 Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +IFNA8 IFN-alphaB ENSG00000120242 Interferon alpha 8 9 21409147-21410185 Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +GRIA2 GluA2, GLUR2, GLURB ENSG00000120251 Glutamate ionotropic receptor AMPA type subunit 2 4 157204182-157366075 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB007812, HPA008441 Enhanced Group enriched Tissue enriched 7 cerebral cortex: 206.6 endometrium: 27.5 Cell line enriched 8 SCLC-21H: 19.9 +NUP43 bA350J20.1, FLJ13287 ENSG00000120253 Nucleoporin 43 6 149724315-149749665 Predicted intracellular proteins, Transporters Evidence at protein level HPA027126, HPA027291, HPA028500 Enhanced Liver cancer:7.13e-7 (unfavourable), Breast cancer:2.08e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 18.6 Expressed in all +MTHFD1L DKFZP586G1517, FLJ21145, FTHFSDC1 ENSG00000120254 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 6 150865549-151101887 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015006, HPA029040, HPA029041, HPA050052, HPA074911 Approved Supported Mitochondria Cervical cancer:1.68e-5 (unfavourable), Liver cancer:8.33e-5 (unfavourable), Urothelial cancer:8.69e-5 (unfavourable), Head and neck cancer:5.10e-4 (unfavourable), Endometrial cancer:7.28e-4 (unfavourable) Expressed in all Mixed placenta: 20.6 Expressed in all +LRP11 bA350J20.3, MANSC3 ENSG00000120256 LDL receptor related protein 11 6 149818798-149864026 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA064002 Approved Mitochondria Breast cancer:2.31e-8 (unfavourable), Liver cancer:2.01e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 89.2 Mixed +CCDC170 bA282P11.1, C6orf97, FLJ23305 ENSG00000120262 Coiled-coil domain containing 170 6 151494030-151621193 Predicted intracellular proteins Evidence at protein level HPA027114, HPA027185 Enhanced Approved Golgi apparatus
Cell Junctions Endometrial cancer:3.64e-4 (favourable) Mixed Tissue enriched 6 fallopian tube: 53.5 thyroid gland: 9.4 Group enriched 6 MCF7: 7.9;T-47d: 5.5 +PCMT1 ENSG00000120265 Protein-L-isoaspartate (D-aspartate) O-methyltransferase 6 149749443-149811420 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003239 Approved Supported Cytosol Breast cancer:4.02e-7 (unfavourable), Head and neck cancer:1.88e-4 (unfavourable), Liver cancer:2.58e-4 (unfavourable), Endometrial cancer:4.27e-4 (unfavourable), Urothelial cancer:6.38e-4 (unfavourable), Cervical cancer:9.58e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 194.7 Expressed in all +PLEKHG1 ARHGEF41, KIAA1209 ENSG00000120278 Pleckstrin homology and RhoGEF domain containing G1 6 150599883-150843665 Predicted intracellular proteins Evidence at protein level HPA027128, HPA027319, HPA028270 Approved Enhanced Nucleoplasm Expressed in all Tissue enhanced spleen: 48.4 lymph node: 23.1 Cell line enhanced AF22: 18.8;HAP1: 29.5;Karpas-707: 16.8 +MYCT1 FLJ21269, MTLC ENSG00000120279 Myc target 1 6 152697895-152724567 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047992 Uncertain Nucleoplasm Renal cancer:4.73e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 69.0 placenta: 29.9 Cell line enhanced HEL: 20.7;HUVEC TERT2: 103.9;TIME: 85.0 +CXorf21 FLJ11577 ENSG00000120280 Chromosome X open reading frame 21 X 30558824-30577844 Predicted intracellular proteins Evidence at protein level HPA001185 Uncertain Approved Nucleoplasm
Vesicles Mixed Mixed appendix: 14.4 Cell line enriched 6 THP-1: 107.8 +MAGEB4 CT3.6, MGC33144 ENSG00000120289 MAGE family member B4 X 30242052-30244193 Predicted intracellular proteins Evidence at protein level HPA030456 Enhanced Not detected Group enriched 117 epididymis: 34.1;testis: 17.0 breast: 0.2 Not detected +CYSTM1 C5orf32, ORF1-FL49 ENSG00000120306 Cysteine rich transmembrane module containing 1 5 140174642-140282052 Predicted intracellular proteins Evidence at protein level HPA050930 Enhanced Renal cancer:9.69e-5 (favourable), Endometrial cancer:1.31e-4 (favourable), Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all stomach: 484.3 Expressed in all +WDR55 FLJ20195, FLJ21702 ENSG00000120314 WD repeat domain 55 5 140664676-140674124 Predicted intracellular proteins Evidence at protein level HPA043470, HPA048143 Uncertain Approved Nucleus
Nucleoli Liver cancer:8.88e-6 (unfavourable), Breast cancer:1.51e-4 (unfavourable) Expressed in all Expressed in all appendix: 12.7 Expressed in all +ARAP3 CENTD3, DRAG1, FLJ21065 ENSG00000120318 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 5 141653401-141682221 Predicted intracellular proteins Evidence at protein level HPA042887 Uncertain Renal cancer:1.59e-6 (unfavourable) Expressed in all Mixed placenta: 17.2 Cell line enhanced HUVEC TERT2: 62.0;TIME: 43.4 +PCDHB8 PCDH-BETA8, PCDH3I ENSG00000120322 Protocadherin beta 8 5 141177790-141180529 Predicted membrane proteins Evidence at transcript level HPA057773 Uncertain Mixed Mixed endometrium: 2.1 Cell line enhanced EFO-21: 19.7;T-47d: 29.4;U-138 MG: 12.0;U-2197: 31.8 +PCDHB10 ENSG00000120324 Protocadherin beta 10 5 141192353-141195642 Predicted membrane proteins Evidence at protein level HPA013445 Uncertain Mixed Tissue enhanced cerebral cortex: 8.3 endometrium: 5.1 Cell line enhanced EFO-21: 13.2 +PCDHB14 PCDH-BETA14 ENSG00000120327 Protocadherin beta 14 5 141222932-141227759 Predicted membrane proteins Evidence at protein level HPA007692, HPA045248 Uncertain Approved Vesicles Renal cancer:6.09e-4 (unfavourable) Mixed Mixed parathyroid gland: 7.6 Cell line enhanced SH-SY5Y: 15.2;SiHa: 12.6 +PCDHB12 PCDH-BETA12 ENSG00000120328 Protocadherin beta 12 5 141208697-141212571 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA045042 Uncertain Approved Plasma membrane Mixed Mixed endometrium: 3.6 Cell line enhanced EFO-21: 2.8;RH-30: 3.1 +SLC25A2 ORNT2 ENSG00000120329 Solute carrier family 25 member 2 5 141302629-141304045 Predicted membrane proteins, Transporters Evidence at protein level HPA042146 Uncertain Not detected Tissue enriched 117 testis: 11.6 all non-specific tissues: 0.0 Not detected +TNN ENSG00000120332 Tenascin N 1 175067858-175148066 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB010907, HPA026726, HPA026764 Uncertain Tissue enhanced Tissue enhanced adipose tissue: 12.4 breast: 4.1 Group enriched 11 AF22: 5.6;NB-4: 2.3;THP-1: 7.4;U-266/70: 2.1;U-937: 1.6 +MRPS14 HSMRPS14 ENSG00000120333 Mitochondrial ribosomal protein S14 1 175010789-175023425 Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA051087 Uncertain Supported Nuclear membrane
Mitochondria Expressed in all Expressed in all thyroid gland: 39.0 Expressed in all +CENPL C1orf155, dJ383J4.3, FLJ31044 ENSG00000120334 Centromere protein L 1 173799550-173824720 Predicted intracellular proteins Evidence at protein level HPA044520 Uncertain Melanoma:2.51e-4 (unfavourable), Ovarian cancer:3.60e-4 (favourable) Expressed in all Tissue enhanced testis: 18.2 lymph node: 7.8 Expressed in all +TNFSF18 AITRL, hGITRL, TL6 ENSG00000120337 Tumor necrosis factor superfamily member 18 1 173039960-173050963 Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 2.8;gallbladder: 3.0 parathyroid gland: 1.4 Group enriched 11 EFO-21: 48.3;HUVEC TERT2: 65.6;TIME: 89.7 +SEC16B LZTR2, PGPR-p117, RGPR, Sec16S ENSG00000120341 SEC16 homolog B, endoplasmic reticulum export factor 1 177923956-177984303 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054292, HPA072913 Enhanced Approved Endoplasmic reticulum
Plasma membrane
Actin filaments Not detected Tissue enhanced duodenum: 28.2;small intestine: 30.9 liver: 18.8 Cell line enhanced CAPAN-2: 6.3;EFO-21: 5.1;HDLM-2: 5.3 +GORAB FLJ11752, GO, NTKL-BP1, SCYL1BP1 ENSG00000120370 Golgin, RAB6 interacting 1 170532129-170553446 Disease related genes, Predicted secreted proteins Evidence at protein level HPA027208, HPA027250 Approved Enhanced Nucleus
Golgi apparatus
Cytosol Renal cancer:7.83e-12 (unfavourable), Head and neck cancer:1.39e-4 (favourable), Liver cancer:5.26e-4 (unfavourable) Expressed in all Mixed thyroid gland: 7.9 Mixed +GPR31 12-HETER, HETER1 ENSG00000120436 G protein-coupled receptor 31 6 167156271-167158329 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA014014, HPA027108 Uncertain Not detected Tissue enhanced lymph node: 1.6 spleen: 0.9 Not detected +ACAT2 ENSG00000120437 Acetyl-CoA acetyltransferase 2 6 159760328-159779055 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB021106, HPA025736, HPA025765, HPA025811 Enhanced Supported Nucleus
Cytosol Colorectal cancer:1.12e-4 (favourable), Endometrial cancer:7.25e-4 (unfavourable), Renal cancer:7.38e-4 (unfavourable) Expressed in all Mixed liver: 45.8 Expressed in all +TCP1 CCT1, Ccta, D6S230E ENSG00000120438 T-complex 1 6 159778498-159789749 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017460, HPA027337, HPA031082 Approved Liver cancer:1.49e-5 (unfavourable), Breast cancer:8.88e-5 (unfavourable) Expressed in all Expressed in all testis: 325.2 Expressed in all +TTLL2 C6orf104, dJ366N23.3, NYD-TSPG ENSG00000120440 Tubulin tyrosine ligase like 2 6 167325086-167359503 Predicted intracellular proteins Evidence at protein level HPA027985 Approved Nuclear membrane
Nucleoli Not detected Tissue enriched 189 testis: 34.1 liver,ovary: 0.1 Cell line enhanced CACO-2: 1.5 +SNX19 CHET8, KIAA0254 ENSG00000120451 Sorting nexin 19 11 130875436-130916509 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013447 Uncertain Supported Mitochondria Renal cancer:3.56e-5 (favourable) Expressed in all Expressed in all testis: 50.8 Mixed +KCNJ5 CIR, GIRK4, KATP1, Kir3.4, LQT13 ENSG00000120457 Potassium voltage-gated channel subfamily J member 5 11 128891356-128921035 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA014722, HPA017353, CAB022569 Enhanced Mixed Tissue enhanced adrenal gland: 84.8 spleen: 18.8 Cell line enriched 12 HBEC3-KT: 9.5 +MSANTD2 C11orf61, FLJ23342 ENSG00000120458 Myb/SANT DNA binding domain containing 2 11 124766498-124800673 Predicted intracellular proteins Evidence at protein level HPA038694, HPA038695 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:2.50e-4 (unfavourable), Urothelial cancer:2.65e-4 (favourable) Expressed in all Mixed endometrium: 14.5 Expressed in all +TP53AIP1 p53AIP1 ENSG00000120471 Tumor protein p53 regulated apoptosis inducing protein 1 11 128934731-128943399 Predicted intracellular proteins Evidence at transcript level HPA044300, HPA048797 Approved Tissue enhanced Tissue enhanced esophagus: 6.3;skin: 22.2 fallopian tube: 4.1 Not detected +TEX11 TGC1, TSGA3 ENSG00000120498 Testis expressed 11 X 70528940-70908731 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA002950 Approved Tissue enhanced Group enriched 10 pancreas: 12.3;testis: 21.1 rectum: 1.7 Not detected +ARR3 ARRX ENSG00000120500 Arrestin 3 X 70268305-70281840 Predicted intracellular proteins Evidence at protein level HPA063129 Supported Not detected Tissue enhanced skin: 2.7 lymph node: 1.1 Cell line enhanced Karpas-707: 1.5 +PDZD11 PDZK11 ENSG00000120509 PDZ domain containing 11 X 70286595-70290514 Predicted intracellular proteins Evidence at protein level HPA003972 Approved Expressed in all Expressed in all cerebral cortex,thyroid gland: 59.9 Expressed in all +SLC10A7 C4orf13, DKFZp313H0531, DKFZp566M114, DKFZp779O2438, MGC25043 ENSG00000120519 Solute carrier family 10 member 7 4 146253975-146521964 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039996, HPA057906 Uncertain Approved Nucleoli Expressed in all Mixed epididymis: 16.2 Expressed in all +NUDCD1 CML66, FLJ14991 ENSG00000120526 NudC domain containing 1 8 109240919-109334385 Predicted intracellular proteins Evidence at protein level HPA023183 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:8.71e-6 (unfavourable), Liver cancer:1.39e-5 (unfavourable), Lung cancer:4.37e-5 (unfavourable), Pancreatic cancer:6.94e-4 (unfavourable) Expressed in all Mixed testis: 24.2 Expressed in all +ENY2 DC6, FLJ20480, Sus1 ENSG00000120533 ENY2, transcription and export complex 2 subunit 8 109334324-109345953 Predicted intracellular proteins, Transporters Evidence at protein level HPA024648 Approved Approved Nucleoplasm
Mitochondria Renal cancer:7.17e-6 (unfavourable) Expressed in all Expressed in all kidney: 77.5 Expressed in all +MASTL FLJ14813, Gwl, THC2 ENSG00000120539 Microtubule associated serine/threonine kinase like 10 27154824-27186924 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027175, HPA054273 Approved Enhanced Nucleoplasm Renal cancer:1.71e-6 (unfavourable), Liver cancer:2.52e-6 (unfavourable), Pancreatic cancer:4.81e-5 (unfavourable) Expressed in all Mixed testis: 12.6 Expressed in all +KIAA1217 DKFZP761L0424, SKT ENSG00000120549 KIAA1217 10 23694746-24547848 Predicted intracellular proteins Evidence at protein level HPA004941 Approved Approved Nucleus
Cytosol Pancreatic cancer:7.63e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 87.7 Cell line enhanced BEWO: 79.6 +LYZL1 LYC2, MGC33408 ENSG00000120563 Lysozyme like 1 10 29289061-29318328 Enzymes, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 480 testis: 53.4 parathyroid gland: 0.1 Not detected +PLXDC2 FLJ14623, TEM7R ENSG00000120594 Plexin domain containing 2 10 19816239-20289856 Predicted membrane proteins Evidence at protein level HPA017268, HPA070793 Approved Supported Nuclear bodies Expressed in all Mixed gallbladder: 25.0 Cell line enhanced HHSteC: 14.9;U-2197: 40.1 +EPC1 Epl1 ENSG00000120616 Enhancer of polycomb homolog 1 10 32267751-32378798 Predicted intracellular proteins Evidence at protein level Pancreatic cancer:6.02e-4 (favourable), Head and neck cancer:6.40e-4 (favourable) Expressed in all Expressed in all endometrium: 32.9 Expressed in all +IQSEC3 KIAA1110, MGC30156 ENSG00000120645 IQ motif and Sec7 domain 3 12 66765-178460 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 16.1 fallopian tube: 5.4 Cell line enhanced HEL: 6.3;U-266/70: 6.9;U-266/84: 1.6 +CCDC77 MGC13183 ENSG00000120647 Coiled-coil domain containing 77 12 389273-442645 Predicted intracellular proteins Evidence at protein level HPA038854 Approved Approved Nuclear membrane Liver cancer:8.11e-7 (unfavourable) Expressed in all Mixed testis: 22.9 Expressed in all +TAF12 TAF2J, TAFII20 ENSG00000120656 TATA-box binding protein associated factor 12 1 28589323-28643085 Predicted intracellular proteins Evidence at protein level HPA008519 Approved Renal cancer:1.36e-7 (unfavourable), Liver cancer:1.16e-4 (unfavourable) Expressed in all Expressed in all testis: 37.1 Expressed in all +ENOX1 cCNOX, CNOX, FLJ10094, PIG38 ENSG00000120658 Ecto-NOX disulfide-thiol exchanger 1 13 43213518-43786908 Predicted intracellular proteins Evidence at protein level HPA038355 Supported Supported Plasma membrane Mixed Tissue enhanced testis: 16.3 cerebral cortex: 10.5 Cell line enhanced hTEC/SVTERT24-B: 17.3;RH-30: 23.3 +TNFSF11 CD254, ODF, OPGL, RANKL, TRANCE ENSG00000120659 Tumor necrosis factor superfamily member 11 13 42562736-42608013 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009193, HPA045142 Enhanced Mixed Tissue enhanced lymph node: 17.3 appendix: 6.3 Cell line enhanced HSkMC: 1.5;NTERA-2: 3.0 +MTRF1 MGC47721, MTTRF1, RF1 ENSG00000120662 Mitochondrial translation release factor 1 13 41216369-41263577 Predicted intracellular proteins Evidence at protein level HPA043316 Uncertain Expressed in all Expressed in all testis: 25.6 Expressed in all +SOHLH2 bHLHe81, FLJ20449, SPATA28, TEB1 ENSG00000120669 Spermatogenesis and oogenesis specific basic helix-loop-helix 2 13 36168208-36214615 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA029182 Mixed Tissue enriched 15 testis: 46.2 prostate: 3.0 Cell line enhanced A-431: 7.0;HL-60: 8.5;Karpas-707: 8.3;NB-4: 9.8;U-266/84: 11.1 +DNAJC15 DNAJD1, MCJ ENSG00000120675 DnaJ heat shock protein family (Hsp40) member C15 13 43023203-43114224 Disease related genes, Predicted membrane proteins Evidence at protein level Expressed in all Mixed cerebral cortex: 11.4 Mixed +PROSER1 bA50D16.2, C13orf23, FLJ12661 ENSG00000120685 Proline and serine rich 1 13 39009866-39038076 Predicted intracellular proteins Evidence at protein level CAB034225, HPA055687 Uncertain Approved Nucleus
Cytosol Expressed in all Expressed in all placenta: 30.3 Expressed in all +UFM1 bA131P10.1, C13orf20 ENSG00000120686 Ubiquitin fold modifier 1 13 38349849-38363619 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039758 Approved Head and neck cancer:1.08e-4 (unfavourable), Endometrial cancer:9.35e-4 (favourable) Expressed in all Expressed in all endometrium: 101.2 Expressed in all +WBP4 FBP21, MGC117310 ENSG00000120688 WW domain binding protein 4 13 41061274-41084006 Predicted intracellular proteins Evidence at protein level HPA038965, HPA058738 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Thyroid cancer:2.89e-4 (favourable) Expressed in all Expressed in all endometrium: 27.7 Expressed in all +ELF1 ENSG00000120690 E74 like ETS transcription factor 1 13 40932028-41061440 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001755, CAB005172 Approved Supported Nucleoplasm Expressed in all Expressed in all bone marrow: 129.2 Expressed in all +SMAD9 MADH6, MADH9, SMAD8, SMAD8/9 ENSG00000120693 SMAD family member 9 13 36844831-36920765 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009119, HPA031162 Approved Supported Nucleoplasm
Cytosol Glioma:4.39e-4 (favourable), Thyroid cancer:4.92e-4 (unfavourable) Mixed Tissue enhanced thyroid gland: 62.8 prostate: 22.2 Cell line enhanced SH-SY5Y: 41.4 +HSPH1 HSP105A, HSP105B, KIAA0201, NY-CO-25 ENSG00000120694 Heat shock protein family H (Hsp110) member 1 13 31134974-31162388 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB002060, HPA028675, HPA031569 Enhanced Enhanced Nucleoplasm
Cytosol Liver cancer:1.41e-5 (unfavourable), Head and neck cancer:4.90e-4 (unfavourable) Expressed in all Expressed in all testis: 123.7 Expressed in all +KBTBD7 DKFZP434E2318 ENSG00000120696 Kelch repeat and BTB domain containing 7 13 41189833-41194566 Predicted intracellular proteins Evidence at protein level HPA043709, HPA046861, HPA048914 Uncertain Lung cancer:5.29e-4 (favourable), Pancreatic cancer:6.62e-4 (favourable) Expressed in all Mixed cerebral cortex: 11.0 Mixed +ALG5 bA421P11.2 ENSG00000120697 ALG5, dolichyl-phosphate beta-glucosyltransferase 13 36949775-37000261 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007989 Approved Approved Cytosol Renal cancer:1.40e-5 (favourable), Head and neck cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 96.6 Expressed in all +EXOSC8 bA421P11.3, CIP3, EAP2, OIP2, p9, RRP43, Rrp43p ENSG00000120699 Exosome component 8 13 36998816-37009613 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB034240, HPA039702, HPA043942 Uncertain Approved Mitochondria Renal cancer:8.39e-7 (unfavourable) Expressed in all Expressed in all testis: 48.7 Expressed in all +ETF1 ERF, ERF1, RF1, SUP45L1, TB3-1 ENSG00000120705 Eukaryotic translation termination factor 1 5 138506095-138543300 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011686, HPA037511 Approved Colorectal cancer:9.33e-5 (favourable), Thyroid cancer:1.22e-4 (unfavourable), Liver cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all testis: 108.6 Expressed in all +TGFBI BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1 ENSG00000120708 Transforming growth factor beta induced 5 136028895-136063818 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008612, HPA017019 Enhanced Renal cancer:7.82e-10 (unfavourable), Cervical cancer:1.03e-5 (unfavourable), Ovarian cancer:1.14e-5 (unfavourable), Endometrial cancer:1.17e-4 (favourable) Expressed in all Expressed in all placenta: 607.8 Cell line enhanced fHDF/TERT166: 2100.5;HSkMC: 1955.4;U-87 MG: 3543.6 +FAM53C C5orf6 ENSG00000120709 Family with sequence similarity 53 member C 5 138331935-138349729 Predicted intracellular proteins Evidence at protein level HPA042796 Approved Endometrial cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all testis: 73.2 Expressed in all +SIL1 BAP, MSS, ULG5 ENSG00000120725 SIL1 nucleotide exchange factor 5 138946720-139293557 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011949 Enhanced Glioma:3.77e-4 (unfavourable), Endometrial cancer:4.34e-4 (favourable) Expressed in all Expressed in all thyroid gland: 60.1 Expressed in all +PAIP2 PAIP2A ENSG00000120727 Poly(A) binding protein interacting protein 2 5 139341587-139369720 Predicted intracellular proteins Evidence at protein level HPA035945, CAB037212, HPA056766 Approved Supported Vesicles Expressed in all Expressed in all testis: 306.7 Expressed in all +MYOT LGMD1, LGMD1A, TTID ENSG00000120729 Myotilin 5 137867791-137887851 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037733, HPA037734 Enhanced Head and neck cancer:8.85e-4 (unfavourable) Tissue enhanced Tissue enriched 21 skeletal muscle: 766.9 esophagus: 36.1 Not detected +KDM3B C5orf7, JMJD1B, KIAA1082, NET22 ENSG00000120733 Lysine demethylase 3B 5 138352596-138437028 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA016610, HPA057202 Supported Enhanced Nucleoplasm Renal cancer:6.67e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 67.3 Expressed in all +EGR1 AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 ENSG00000120738 Early growth response 1 5 138465490-138469315 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB019427, HPA029937, HPA029938 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all ovary: 1188.8 Cell line enhanced hTCEpi: 208.0;U-266/84: 325.4 +SERP1 FLJ43424, RAMP4 ENSG00000120742 Stress associated endoplasmic reticulum protein 1 3 150541994-150603228 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038970 Approved Approved Endoplasmic reticulum Pancreatic cancer:1.03e-5 (unfavourable) Expressed in all Expressed in all epididymis: 182.5 Expressed in all +PLS1 I-plastin, Plastin-1 ENSG00000120756 Plastin 1 3 142596387-142713664 Predicted intracellular proteins Evidence at protein level HPA055744 Enhanced Renal cancer:8.76e-6 (favourable), Pancreatic cancer:4.84e-4 (unfavourable) Mixed Tissue enhanced duodenum: 192.4;small intestine: 348.5 rectum: 152.0 Cell line enhanced BEWO: 108.3;RPTEC TERT1: 108.5 +ZFP30 KIAA0961, ZNF745 ENSG00000120784 ZFP30 zinc finger protein 19 37613749-37692337 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030606 Uncertain Approved Cytosol Renal cancer:3.86e-4 (favourable) Expressed in all Mixed testis: 14.0 Cell line enhanced U-2 OS: 34.4 +NR2C1 TR2, TR2-11 ENSG00000120798 Nuclear receptor subfamily 2 group C member 1 12 95020229-95073703 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035040, HPA035041, HPA067767 Enhanced Supported Nucleus
Cell Junctions
Cytosol Renal cancer:1.03e-6 (unfavourable), Liver cancer:5.18e-5 (unfavourable), Urothelial cancer:5.62e-5 (favourable) Expressed in all Mixed testis: 21.9 Expressed in all +UTP20 1A6/DRIM, DRIM ENSG00000120800 UTP20, small subunit processome component 12 101280109-101386616 Predicted intracellular proteins Evidence at protein level HPA049341 Supported Nucleoli
Plasma membrane Liver cancer:1.15e-5 (unfavourable), Renal cancer:8.87e-4 (favourable) Expressed in all Mixed parathyroid gland: 12.2 Expressed in all +TMPO LAP2, LEMD4, TP ENSG00000120802 Thymopoietin 12 98515512-98550379 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008150, CAB009847 Enhanced Enhanced Nuclear membrane Renal cancer:9.34e-4 (unfavourable) Expressed in all Expressed in all lymph node: 91.3 Expressed in all +ARL1 ARFL1 ENSG00000120805 ADP ribosylation factor like GTPase 1 12 101393120-101407820 Predicted intracellular proteins Evidence at protein level HPA062656, HPA073012 Approved Supported Golgi apparatus Endometrial cancer:1.61e-4 (favourable) Expressed in all Expressed in all thyroid gland: 142.0 Expressed in all +GLT8D2 FLJ31494 ENSG00000120820 Glycosyltransferase 8 domain containing 2 12 103988984-104064183 Predicted intracellular proteins Evidence at protein level HPA026904 Approved Approved Cytosol Renal cancer:1.58e-6 (unfavourable), Cervical cancer:7.37e-4 (unfavourable), Stomach cancer:7.92e-4 (unfavourable) Expressed in all Mixed gallbladder: 57.1 Cell line enhanced ASC TERT1: 48.9;BJ hTERT+: 73.1;HSkMC: 47.3 +MTERF2 FLJ14062, MTERFD3 ENSG00000120832 Mitochondrial transcription termination factor 2 12 106977291-106987166 Predicted intracellular proteins Evidence at protein level HPA003526 Approved Cervical cancer:8.50e-4 (favourable) Expressed in all Expressed in all adrenal gland: 29.1 Mixed +SOCS2 CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2 ENSG00000120833 Suppressor of cytokine signaling 2 12 93569814-93583487 Predicted intracellular proteins Evidence at protein level CAB010356 Approved Approved Endoplasmic reticulum Pancreatic cancer:8.17e-7 (favourable), Liver cancer:1.09e-6 (favourable) Expressed in all Expressed in all smooth muscle: 130.2 Cell line enhanced CACO-2: 137.8;K-562: 124.1;REH: 295.4 +NFYB CBF-A, HAP3, NF-YB ENSG00000120837 Nuclear transcription factor Y subunit beta 12 104117077-104138289 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004211 Supported Supported Nucleoplasm Renal cancer:9.28e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 123.9 Expressed in all +WASHC3 CCDC53, CGI-116 ENSG00000120860 WASH complex subunit 3 12 102012927-102062149 Predicted intracellular proteins Evidence at protein level HPA038338, HPA038339 Approved Approved Vesicles Expressed in all Expressed in all testis: 165.7 Expressed in all +APAF1 APAF-1, CED4 ENSG00000120868 Apoptotic peptidase activating factor 1 12 98645141-98735433 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031373, CAB069399 Enhanced Approved Nucleoplasm
Golgi apparatus
Cytosol Colorectal cancer:5.90e-4 (favourable) Expressed in all Mixed bone marrow: 21.7 Expressed in all +DUSP4 HVH2, MKP-2, TYP ENSG00000120875 Dual specificity phosphatase 4 8 29333064-29350668 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA061967 Supported Nucleoplasm Renal cancer:4.19e-4 (unfavourable) Expressed in all Tissue enhanced breast: 29.6 stomach: 28.2 Cell line enhanced A549: 90.3;SK-MEL-30: 120.4;WM-115: 120.9 +CLU APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2 ENSG00000120885 Clusterin 8 27596917-27615031 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000572, CAB016253 Enhanced Thyroid cancer:7.66e-5 (favourable) Expressed in all Expressed in all epididymis: 11170.2 Expressed in all +TNFRSF10B CD262, DR5, KILLER, TRAIL-R2, TRICK2A, TRICKB ENSG00000120889 TNF receptor superfamily member 10b 8 23020133-23069179 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA023625 Approved Renal cancer:1.76e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 33.3 Mixed +SORBS3 SCAM-1, SH3D4, vinexin ENSG00000120896 Sorbin and SH3 domain containing 3 8 22544986-22575788 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015849, HPA048034 Approved Approved Nucleoplasm
Focal adhesion sites Urothelial cancer:1.53e-5 (unfavourable), Pancreatic cancer:4.88e-4 (favourable) Expressed in all Expressed in all placenta: 95.6 Mixed +PTK2B CADTK, CAKB, FAK2, PTK, PYK2, RAFTK ENSG00000120899 Protein tyrosine kinase 2 beta 8 27311482-27459391 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003850, HPA026091, HPA026276 Approved Enhanced Plasma membrane
Cytosol Cervical cancer:3.32e-4 (favourable), Thyroid cancer:5.11e-4 (favourable) Expressed in all Expressed in all lymph node: 91.1 Cell line enhanced REH: 128.1 +CHRNA2 ENSG00000120903 Cholinergic receptor nicotinic alpha 2 subunit 8 27459761-27479883 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 24 prostate: 46.8 breast: 1.9 Not detected +ADRA1A ADRA1C, ADRA1L1 ENSG00000120907 Adrenoceptor alpha 1A 8 26748150-26867273 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA029678, HPA029679 Approved Tissue enhanced Tissue enhanced adipose tissue: 22.6;liver: 31.6;prostate: 20.8 seminal vesicle: 19.1 Not detected +PPP3CC CALNA3, PP2Bgamma ENSG00000120910 Protein phosphatase 3 catalytic subunit gamma 8 22440819-22541142 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023396, CAB024950 Approved Approved Vesicles Lung cancer:6.80e-5 (favourable) Expressed in all Expressed in all testis: 101.2 Expressed in all +PDLIM2 ENSG00000120913 PDZ and LIM domain 2 8 22578279-22598025 Predicted intracellular proteins Evidence at protein level HPA003880 Approved Approved Actin filaments
Focal adhesion sites Renal cancer:1.37e-7 (unfavourable), Glioma:7.23e-4 (unfavourable) Expressed in all Expressed in all spleen: 267.3 Mixed +EPHX2 ENSG00000120915 Epoxide hydrolase 2 8 27490779-27545564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023094, HPA023660 Approved Enhanced Cytosol Renal cancer:1.98e-10 (favourable), Cervical cancer:2.45e-4 (favourable) Expressed in all Expressed in all kidney: 171.7 Cell line enhanced K-562: 46.0 +RNF170 ADSA, DKFZP564A022, SNAX1 ENSG00000120925 Ring finger protein 170 8 42849637-42897290 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA050931, HPA054621 Uncertain Expressed in all Expressed in all thyroid gland: 47.9 Expressed in all +NPPB ENSG00000120937 Natriuretic peptide B 1 11857464-11858931 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 1857 heart muscle: 3255.2 testis: 1.7 Group enriched 7 BEWO: 134.5;CACO-2: 309.8 +UBIAD1 SCCD, TERE1 ENSG00000120942 UbiA prenyltransferase domain containing 1 1 11273206-11296049 Disease related genes, Predicted membrane proteins Evidence at protein level HPA044862 Approved Vesicles Renal cancer:6.80e-5 (favourable) Expressed in all Expressed in all fallopian tube: 15.8 Expressed in all +TARDBP ALS10, TDP-43 ENSG00000120948 TAR DNA binding protein 1 11012344-11026420 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003703, HPA017284 Supported Enhanced Nucleoplasm Liver cancer:1.20e-7 (unfavourable), Cervical cancer:1.15e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 178.4 Expressed in all +TNFRSF8 CD30, D1S166E, KI-1 ENSG00000120949 TNF receptor superfamily member 8 1 12063377-12144207 Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000016, HPA032081, HPA032082 Approved Tissue enriched Tissue enhanced appendix: 4.1 adipose tissue: 3.1 Cell line enriched 22 HDLM-2: 528.2 +PRAMEF2 FLJ43580 ENSG00000120952 PRAME family member 2 1 12857086-12861909 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.2 Not detected +ZNF706 HSPC038 ENSG00000120963 Zinc finger protein 706 8 101177878-101206193 Predicted intracellular proteins Evidence at protein level HPA042793 Approved Plasma membrane Renal cancer:5.90e-11 (unfavourable), Endometrial cancer:3.12e-5 (unfavourable) Expressed in all Expressed in all skin: 159.9 Expressed in all +LYPLA1 LPL1 ENSG00000120992 Lysophospholipase I 8 54046367-54102017 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050941, HPA063151 Enhanced Approved Nucleoplasm
Cytosol Pancreatic cancer:2.34e-4 (unfavourable) Expressed in all Expressed in all testis: 118.6 Expressed in all +CRISPLD1 Cocoacrisp, DKFZp762F133, LCRISP1 ENSG00000121005 Cysteine rich secretory protein LCCL domain containing 1 8 74984515-75034558 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024725 Uncertain Tissue enhanced Tissue enhanced prostate: 39.6 breast: 35.0 Group enriched 5 AF22: 132.6;SH-SY5Y: 76.5 +COPS5 CSN5, JAB1, MOV-34, SGN5 ENSG00000121022 COP9 signalosome subunit 5 8 67043079-67083783 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004242, HPA004845, HPA051531 Supported Enhanced Nucleoplasm Expressed in all Expressed in all testis: 92.4 Expressed in all +RDH10 SDR16C4 ENSG00000121039 Retinol dehydrogenase 10 8 73294612-73325281 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049199 Approved Lipid droplets Expressed in all Expressed in all placenta: 51.8 Expressed in all +EPX EPO, EPP, EPX-PEN ENSG00000121053 Eosinophil peroxidase 17 58192737-58205174 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA050507 Approved Not detected Tissue enriched 24 bone marrow: 20.5 cerebral cortex: 0.8 Cell line enriched 55 NB-4: 157.0 +AKAP1 AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, S-AKAP84, SAKAP84, TDRD17 ENSG00000121057 A-kinase anchoring protein 1 17 57085092-57121349 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008620, HPA008691, CAB019286 Supported Supported Mitochondria Renal cancer:7.86e-9 (favourable) Expressed in all Expressed in all testis: 150.9 Expressed in all +COIL CLN80, p80-coilin ENSG00000121058 Coilin 17 56938187-56961054 Predicted intracellular proteins Evidence at protein level CAB017524, HPA027885, HPA068537, CAB069400 Enhanced Enhanced Nucleus
Nucleoli fibrillar center
Nuclear bodies Liver cancer:1.28e-4 (unfavourable), Colorectal cancer:1.77e-4 (favourable) Expressed in all Tissue enriched 9 testis: 175.4 thyroid gland: 20.2 Expressed in all +TRIM25 EFP, RNF147, ZNF147 ENSG00000121060 Tripartite motif containing 25 17 56887909-56914038 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005909 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Pancreatic cancer:3.36e-4 (favourable), Stomach cancer:9.35e-4 (favourable), Liver cancer:9.37e-4 (unfavourable) Expressed in all Expressed in all skin: 34.8 Mixed +SCPEP1 RISC ENSG00000121064 Serine carboxypeptidase 1 17 56978105-57006768 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039102, HPA057200 Approved Approved Golgi apparatus Liver cancer:1.96e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 621.6 Expressed in all +SPOP BTBD32, TEF2 ENSG00000121067 Speckle type BTB/POZ protein 17 49598884-49678234 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Liver cancer:6.88e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 121.2 Expressed in all +TBX2 ENSG00000121068 T-box 2 17 61399896-61409466 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008586, CAB013636 Approved Approved Nucleoplasm
Cytosol Expressed in all Tissue enhanced lung: 50.0 seminal vesicle: 40.0 Cell line enhanced AN3-CA: 124.2;MCF7: 62.0;SH-SY5Y: 65.7;WM-115: 44.0 +SLC35B1 UGTREL1 ENSG00000121073 Solute carrier family 35 member B1 17 49700943-49709014 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA048655, HPA057418 Approved Approved Nucleus
Endoplasmic reticulum
Vesicles Renal cancer:5.69e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 52.2 Expressed in all +TBX4 ENSG00000121075 T-box 4 17 61452404-61485110 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB032413, HPA044457 Uncertain Approved Vesicles Mixed Group enriched 6 lung: 43.6;placenta: 29.8;prostate: 14.9 urinary bladder: 4.8 Cell line enhanced BJ: 2.4;THP-1: 3.9 +TEX14 CT113 ENSG00000121101 Testis expressed 14, intercellular bridge forming factor 17 58556678-58692055 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA030620, HPA077020 Enhanced Approved Vesicles
Plasma membrane
Cell Junctions
Cytosol Mixed Tissue enriched 43 testis: 48.9 bone marrow: 1.1 Cell line enhanced HDLM-2: 5.9;Karpas-707: 5.7;MCF7: 2.5 +FAM117A ENSG00000121104 Family with sequence similarity 117 member A 17 49710332-49789180 Predicted intracellular proteins Evidence at protein level HPA022531 Approved Approved Nucleoplasm Lung cancer:8.25e-7 (favourable), Breast cancer:5.30e-5 (favourable), Pancreatic cancer:1.81e-4 (favourable) Expressed in all Expressed in all spleen: 46.6 Cell line enhanced U-266/70: 61.5 +NCAPH BRRN1, CAP-H, hCAP-H ENSG00000121152 Non-SMC condensin I complex subunit H 2 96335787-96373845 Predicted intracellular proteins Evidence at protein level HPA002647, HPA003008 Enhanced Supported Nucleus
Cytosol Liver cancer:9.53e-6 (unfavourable), Pancreatic cancer:1.02e-4 (unfavourable), Lung cancer:6.73e-4 (unfavourable) Expressed in all Tissue enhanced testis: 55.4 lymph node: 21.3 Mixed +LRAT LCA14 ENSG00000121207 Lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 4 154626945-154753118 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA070726 Uncertain Endoplasmic reticulum
Golgi apparatus Mixed Tissue enhanced thyroid gland: 2.3 testis: 1.6 Cell line enriched 11 NTERA-2: 11.7 +KIAA0922 DKFZp586H1322, TMEM131L ENSG00000121210 KIAA0922 4 153466346-153636711 Predicted membrane proteins Evidence at protein level HPA043472, HPA048443 Uncertain Approved Nucleoli fibrillar center
Vesicles Cervical cancer:6.69e-6 (favourable) Expressed in all Expressed in all lymph node: 56.4 Cell line enhanced Daudi: 75.0;MOLT-4: 79.8;U-698: 85.3 +MND1 GAJ ENSG00000121211 Meiotic nuclear divisions 1 4 153344649-153415118 Predicted intracellular proteins Evidence at protein level HPA043499 Enhanced Liver cancer:2.72e-4 (unfavourable), Melanoma:3.40e-4 (unfavourable) Expressed in all Tissue enhanced testis: 28.8 lymph node: 14.3 Mixed +TRIM6 RNF89 ENSG00000121236 Tripartite motif containing 6 11 5596109-5612958 Enzymes, Predicted intracellular proteins Evidence at protein level HPA060514 Uncertain Mixed Tissue enhanced kidney: 22.5 testis: 17.2 Cell line enhanced NTERA-2: 22.2;U-2 OS: 22.5 +ABCC11 MRP8 ENSG00000121270 ATP binding cassette subfamily C member 11 16 48166910-48247568 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031980, HPA031981, HPA031982, CAB032513 Uncertain Group enriched Tissue enriched 11 breast: 64.4 prostate: 6.0 Cell line enriched 5 T-47d: 64.4 +PAPD5 TRF4-2 ENSG00000121274 Poly(A) RNA polymerase D5, non-canonical 16 50152918-50235310 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042968, HPA048225 Uncertain Renal cancer:1.85e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.5 Expressed in all +ADCY7 AC7, KIAA0037 ENSG00000121281 Adenylate cyclase 7 16 50246137-50318135 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041218, HPA048241 Uncertain Approved Cytosol Cervical cancer:5.31e-4 (unfavourable) Mixed Mixed spleen: 44.0 Cell line enhanced HMC-1: 186.7;RPMI-8226: 76.6 +CEP89 CCDC123, FLJ14640 ENSG00000121289 Centrosomal protein 89 19 32875925-32971991 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039382, HPA040056 Supported Plasma membrane
Cytosol Liver cancer:8.78e-5 (unfavourable) Expressed in all Mixed fallopian tube,prostate: 14.5 Expressed in all +TSHZ3 KIAA1474, TSH3, ZNF537 ENSG00000121297 Teashirt zinc finger homeobox 3 19 31274945-31349547 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008834 Approved Supported Nucleoplasm Renal cancer:2.92e-4 (unfavourable) Mixed Mixed ovary: 37.5 Cell line enhanced RH-30: 44.3;U-138 MG: 31.7 +ECHDC2 FLJ10948 ENSG00000121310 Enoyl-CoA hydratase domain containing 2 1 52895910-52927212 Predicted intracellular proteins Evidence at protein level HPA026731, HPA026768 Enhanced Approved Mitochondria Urothelial cancer:2.70e-4 (favourable), Head and neck cancer:6.65e-4 (favourable) Expressed in all Tissue enhanced liver: 47.8 kidney: 26.3 Cell line enhanced BEWO: 15.6;HHSteC: 9.5 +TAS2R8 T2R8, TRB5 ENSG00000121314 Taste 2 receptor member 8 12 10806051-10807293 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +PLBD1 FLJ22662 ENSG00000121316 Phospholipase B domain containing 1 12 14503661-14568349 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040303 Approved Liver cancer:2.81e-5 (unfavourable), Pancreatic cancer:1.66e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 167.1 Cell line enhanced BEWO: 77.7;CAPAN-2: 186.4 +TAS2R10 T2R10, TRB2 ENSG00000121318 Taste 2 receptor member 10 12 10825317-10826358 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected breast,epididymis: 0.2 Not detected +PRB2 cP7, PRPPRB1, Ps ENSG00000121335 Proline rich protein BstNI subfamily 2 12 11391540-11501041 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 4978 salivary gland: 4971.2 bone marrow,skin: 0.9 Not detected +PYROXD1 DKFZp762G094, FLJ22028 ENSG00000121350 Pyridine nucleotide-disulphide oxidoreductase domain 1 12 21437615-21471252 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038319, HPA038320 Uncertain Approved Nuclear speckles Urothelial cancer:1.70e-4 (favourable) Expressed in all Expressed in all thyroid gland: 26.4 Expressed in all +IAPP AMYLIN, DAP, IAP ENSG00000121351 Islet amyloid polypeptide 12 21354959-21379978 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000352, HPA053194 Enhanced Tissue enriched Tissue enriched 7 pancreas: 35.0 testis: 5.3 Cell line enhanced U-2 OS: 1.3 +KCNJ8 Kir6.1 ENSG00000121361 Potassium voltage-gated channel subfamily J member 8 12 21764955-21775581 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA031066 Uncertain Renal cancer:1.62e-6 (unfavourable), Colorectal cancer:9.29e-4 (unfavourable) Expressed in all Mixed seminal vesicle: 32.0 Cell line enhanced CACO-2: 71.9;SH-SY5Y: 31.1 +TAS2R7 T2R7, TRB4 ENSG00000121377 Taste 2 receptor member 7 12 10801532-10802627 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +BCL2L14 BCL-G, BCLG ENSG00000121380 BCL2 like 14 12 12049844-12211084 Predicted intracellular proteins Evidence at protein level HPA040665 Enhanced Uncertain Cytosol Tissue enhanced Tissue enhanced rectum: 16.9;testis: 24.1 small intestine: 14.2 Group enriched 5 CAPAN-2: 1.8;NTERA-2: 1.6;RT4: 1.5 +TAS2R9 T2R9, TRB6 ENSG00000121381 Taste 2 receptor member 9 12 10809094-10810168 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +PSPC1 FLJ10955, PSP1 ENSG00000121390 Paraspeckle component 1 13 19674752-19783019 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038904 Supported Approved Nucleoplasm
Nucleoli fibrillar center Thyroid cancer:1.46e-4 (favourable), Liver cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all testis: 45.5 Expressed in all +ZNF549 FLJ34917 ENSG00000121406 Zinc finger protein 549 19 57527325-57557542 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA039511 Uncertain Approved Nucleoplasm
Cytosol Mixed Mixed parathyroid gland: 10.2 Mixed +A1BG ENSG00000121410 Alpha-1-B glycoprotein 19 58345178-58353499 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016673, HPA044252 Supported Liver cancer:3.97e-4 (favourable) Tissue enriched Tissue enriched 331 liver: 505.6 fallopian tube: 1.5 Cell line enhanced HEK 293: 2.2;REH: 3.0 +ZSCAN18 FLJ12895, ZNF447 ENSG00000121413 Zinc finger and SCAN domain containing 18 19 58083838-58118427 Predicted intracellular proteins Evidence at protein level HPA024318 Supported Approved Nucleoplasm Renal cancer:3.95e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 78.8 Cell line enhanced HEK 293: 121.2;SCLC-21H: 73.3 +ZNF211 CH2H2-25, ZNF-25 ENSG00000121417 Zinc finger protein 211 19 57630395-57642779 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA011340, HPA049967 Approved Approved Mitochondria
Rods & Rings Expressed in all Expressed in all parathyroid gland: 32.7 Mixed +PDZRN3 KIAA1095, LNX3, SEMACAP3 ENSG00000121440 PDZ domain containing ring finger 3 3 73382433-73624940 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038822, HPA061420 Approved Supported Nucleus
Cytosol Renal cancer:3.65e-7 (favourable), Endometrial cancer:3.35e-5 (favourable), Pancreatic cancer:4.93e-4 (favourable) Mixed Mixed ovary: 85.7 Cell line enhanced AF22: 31.7;ASC diff: 39.1;BJ hTERT+: 34.1;HSkMC: 30.3 +RGSL1 RGSL2 ENSG00000121446 Regulator of G-protein signaling like 1 1 182409192-182560599 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 6 testis: 9.1 epididymis: 1.4 Not detected +LHX4 Gsh4 ENSG00000121454 LIM homeobox 4 1 180230286-180278982 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055705 Approved Nuclear speckles Not detected Mixed testis: 2.2 Cell line enhanced BEWO: 10.3 +RNF2 BAP-1, BAP1, DING, HIPI3, RING1B, RING2 ENSG00000121481 Ring finger protein 2 1 185045364-185102608 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026803 Uncertain Enhanced Nucleoplasm
Nuclear bodies Renal cancer:1.94e-7 (unfavourable), Liver cancer:1.08e-5 (unfavourable) Expressed in all Expressed in all testis: 42.2 Expressed in all +TRMT1L C1orf25 ENSG00000121486 TRNA methyltransferase 1 like 1 185118098-185157072 Predicted intracellular proteins Evidence at protein level HPA026728 Uncertain Approved Nucleus
Nucleoli Expressed in all Mixed testis: 50.4 Expressed in all +SEC22A SEC22L2 ENSG00000121542 SEC22 homolog A, vesicle trafficking protein 3 123201927-123274130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.48e-4 (unfavourable) Expressed in all Expressed in all testis: 48.7 Expressed in all +CSTA STF1, STFA ENSG00000121552 Cystatin A 3 122325244-122341972 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000469, HPA001031, CAB047315 Enhanced Approved Nucleus
Cytosol Renal cancer:2.60e-6 (unfavourable), Head and neck cancer:5.86e-4 (favourable) Expressed in all Group enriched 5 esophagus: 3876.3;tonsil: 833.8 skin: 429.8 Cell line enhanced hTCEpi: 870.0;THP-1: 525.5;U-698: 341.3 +DPPA4 FLJ10713 ENSG00000121570 Developmental pluripotency associated 4 3 109326141-109337572 Predicted intracellular proteins Evidence at protein level CAB020678, HPA035249, HPA035250 Enhanced Supported Nucleus
Nucleoli Tissue enriched Group enriched 8 bone marrow: 2.8;placenta: 3.0;testis: 7.7 lung,lymph node: 0.5 Cell line enhanced AF22: 42.6;HAP1: 92.5;NTERA-2: 327.0 +POPDC2 POP2 ENSG00000121577 Popeye domain containing 2 3 119636457-119665324 Predicted membrane proteins Evidence at protein level HPA024255 Enhanced Mixed Tissue enhanced heart muscle: 197.3;seminal vesicle: 64.1 smooth muscle: 35.3 Cell line enriched 31 SH-SY5Y: 30.8 +B4GALT4 beta4Gal-T4 ENSG00000121578 Beta-1,4-galactosyltransferase 4 3 119211732-119241103 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046819, HPA063546 Approved Supported Golgi apparatus Liver cancer:4.04e-4 (unfavourable) Expressed in all Expressed in all epididymis: 75.8 Expressed in all +NAA50 FLJ13194, MAK3, NAT13, NAT5, San ENSG00000121579 N(alpha)-acetyltransferase 50, NatE catalytic subunit 3 113716460-113746300 Enzymes, Predicted intracellular proteins Evidence at protein level Liver cancer:1.51e-5 (unfavourable), Pancreatic cancer:7.92e-5 (unfavourable), Endometrial cancer:2.32e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 111.8 Expressed in all +CD80 B7-1, B7.1, CD28LG, CD28LG1 ENSG00000121594 CD80 molecule 3 119524293-119559602 CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025368, HPA050092 Enhanced Mixed Tissue enhanced appendix: 7.2;lymph node: 6.7;tonsil: 6.3 spleen: 4.7 Cell line enhanced Daudi: 8.5;HDLM-2: 39.3;Karpas-707: 12.2;U-266/70: 5.5 +KIF18A DKFZP434G2226, PPP1R99 ENSG00000121621 Kinesin family member 18A 11 28020620-28108308 Predicted intracellular proteins Evidence at protein level HPA039312, HPA039484 Approved Supported Microtubules
Cytokinetic bridge Mixed Tissue enhanced testis: 23.4 lymph node: 5.3 Mixed +GJA8 CAE, CAE1, CX50, CZP1 ENSG00000121634 Gap junction protein alpha 8 1 147907956-147909257 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA014715, HPA062940 Enhanced Not detected Tissue enriched 86 testis: 11.4 kidney,smooth muscle: 0.1 Not detected +DESI2 C1orf121, CGI-146, FAM152A, FLJ21998, PNAS-4, PPPDE1 ENSG00000121644 Desumoylating isopeptidase 2 1 244652935-244709033 Predicted intracellular proteins Evidence at protein level HPA049950 Approved Vesicles Renal cancer:4.25e-5 (unfavourable) Expressed in all Expressed in all testis: 95.0 Expressed in all +MAPK8IP1 IB1, JIP-1, JIP1, PRKM8IP ENSG00000121653 Mitogen-activated protein kinase 8 interacting protein 1 11 45885651-45906465 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058921, HPA070332 Enhanced Plasma membrane Renal cancer:1.23e-11 (favourable) Expressed in all Tissue enriched 5 cerebral cortex: 177.1 parathyroid gland: 33.1 Cell line enhanced SCLC-21H: 89.8 +CRY2 ENSG00000121671 Cryptochrome circadian clock 2 11 45847118-45883248 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037577 Supported Supported Nuclear speckles
Cytosol Renal cancer:6.44e-15 (favourable), Liver cancer:6.82e-5 (favourable), Colorectal cancer:1.67e-4 (unfavourable), Pancreatic cancer:4.39e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 56.2 Expressed in all +PEX16 ENSG00000121680 Peroxisomal biogenesis factor 16 11 45909669-45918812 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA043286 Approved Urothelial cancer:9.06e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 27.5 Expressed in all +DEPDC7 ENSG00000121690 DEP domain containing 7 11 33015864-33033582 Predicted intracellular proteins Evidence at protein level HPA015800 Approved Nucleus
Nucleoli
Cytosol Liver cancer:7.26e-4 (favourable) Mixed Tissue enhanced liver: 37.6;testis: 50.7 small intestine: 31.2 Cell line enhanced LHCN-M2: 44.3;RH-30: 38.6;SiHa: 39.2 +CAT ENSG00000121691 Catalase 11 34438925-34472062 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001515, HPA051282, HPA055838 Enhanced Supported Vesicles
Cytosol Renal cancer:1.96e-8 (favourable), Liver cancer:9.67e-4 (favourable) Expressed in all Expressed in all liver: 625.4 Cell line enhanced HL-60: 310.1 +PILRB FDFACT1, FDFACT2 ENSG00000121716 Paired immunoglobin-like type 2 receptor beta 7 100352176-100367733 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026750 Approved Approved Mitochondria Renal cancer:1.42e-4 (unfavourable) Expressed in all Expressed in all testis: 166.9 Expressed in all +ZMYM2 FIM, MYM, RAMP, ZNF198 ENSG00000121741 Zinc finger MYM-type containing 2 13 19958670-20091829 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031765 Approved Approved Nucleoplasm
Endoplasmic reticulum Urothelial cancer:6.07e-4 (favourable) Expressed in all Expressed in all testis: 88.0 Expressed in all +GJB6 CX30, DFNA3, ED2, EDH, HED ENSG00000121742 Gap junction protein beta 6 13 20221971-20232395 Disease related genes, Predicted membrane proteins Evidence at protein level HPA014846 Supported Cell Junctions Tissue enhanced Group enriched 5 bone marrow: 48.1;cerebral cortex: 39.4;esophagus: 150.1;skin: 32.1 tonsil: 12.2 Cell line enriched 9 RT4: 133.4 +GJA3 CX46, CZP3 ENSG00000121743 Gap junction protein alpha 3 13 20138255-20161049 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA014821 Supported Tissue enhanced Tissue enhanced heart muscle: 5.1;parathyroid gland: 5.9;placenta: 3.5 testis: 2.4 Cell line enhanced CAPAN-2: 6.8;HL-60: 5.2 +TBC1D15 DKFZp761D0223, FLJ12085 ENSG00000121749 TBC1 domain family member 15 12 71839707-71927248 Predicted intracellular proteins Evidence at protein level HPA013388, HPA015592 Supported Supported Mitochondria
Cytosol Renal cancer:5.34e-4 (favourable), Cervical cancer:7.06e-4 (favourable) Expressed in all Expressed in all thyroid gland: 50.9 Expressed in all +ADGRB2 BAI2 ENSG00000121753 Adhesion G protein-coupled receptor B2 1 31727117-31764893 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA052612, HPA054617 Supported Centrosome Lung cancer:4.02e-5 (unfavourable), Breast cancer:6.46e-4 (favourable) Tissue enhanced Tissue enriched 14 cerebral cortex: 72.3 adrenal gland: 5.1 Cell line enhanced SH-SY5Y: 26.4;T-47d: 27.3;U-2 OS: 28.9 +HCRTR1 OX1R ENSG00000121764 Hypocretin receptor 1 1 31617686-31632518 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA014018 Approved Not detected Tissue enhanced adrenal gland: 1.2 cerebral cortex: 0.9 Not detected +ZCCHC17 HSPC251, pNO40, PS1D ENSG00000121766 Zinc finger CCHC-type containing 17 1 31296982-31364953 Predicted intracellular proteins Evidence at protein level HPA053727 Approved Supported Nuclear speckles Liver cancer:3.27e-4 (unfavourable) Expressed in all Expressed in all testis: 78.7 Expressed in all +FABP3 FABP11, H-FABP, MDGI, O-FABP ENSG00000121769 Fatty acid binding protein 3 1 31365625-31376850 Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017830, HPA055754 Enhanced Approved Golgi apparatus Renal cancer:1.54e-7 (favourable) Expressed in all Tissue enriched 6 heart muscle: 2930.0 skeletal muscle: 471.2 Cell line enriched 5 ASC TERT1: 434.0 +KHDRBS1 FLJ34027, p62, Sam68 ENSG00000121774 KH RNA binding domain containing, signal transduction associated 1 1 32013829-32060850 Predicted intracellular proteins Evidence at protein level CAB005355, HPA051280, HPA056813 Enhanced Enhanced Nucleoplasm Liver cancer:3.68e-5 (unfavourable), Renal cancer:9.32e-4 (unfavourable) Expressed in all Expressed in all endometrium: 134.1 Expressed in all +TMEM39B FLJ10315 ENSG00000121775 Transmembrane protein 39B 1 32072031-32102866 Predicted membrane proteins Evidence at protein level HPA040191, HPA040224 Approved Approved Vesicles Renal cancer:5.11e-9 (unfavourable), Liver cancer:2.82e-6 (unfavourable), Endometrial cancer:3.00e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 10.1 Expressed in all +CCRL2 ACKR5, CKRX, CRAM-A, CRAM-B, HCR ENSG00000121797 C-C motif chemokine receptor like 2 3 46407163-46412997 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA043238 Approved Colorectal cancer:3.72e-5 (favourable), Urothelial cancer:9.67e-5 (favourable) Mixed Mixed lung: 17.7 Cell line enhanced HEL: 18.0;PC-3: 14.0;TIME: 12.2 +CCR2 CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R ENSG00000121807 C-C motif chemokine receptor 2 3 46353734-46360928 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB003793 Approved Lung cancer:5.87e-4 (favourable) Mixed Tissue enhanced appendix: 51.7 spleen: 20.5 Cell line enhanced Karpas-707: 195.5;THP-1: 89.5;U-266/70: 473.3;U-266/84: 185.8 +POLR3GL flj32422, MGC3200 ENSG00000121851 RNA polymerase III subunit G like 1 145964702-145978848 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA027288 Uncertain Endometrial cancer:6.52e-5 (favourable), Breast cancer:2.96e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 59.5 Expressed in all +GHSR ENSG00000121853 Growth hormone secretagogue receptor 3 172445133-172448456 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Not detected Not detected adrenal gland: 0.3 Not detected +TNFSF10 Apo-2L, CD253, TL2, TRAIL ENSG00000121858 Tumor necrosis factor superfamily member 10 3 172505508-172523507 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054938 Uncertain Approved Microtubules Pancreatic cancer:9.43e-4 (unfavourable) Expressed in all Expressed in all lung: 260.0 Cell line enhanced BEWO: 70.1;HMC-1: 209.7;RPTEC TERT1: 91.4 +ZNF639 ANC-2H01, ZASC1 ENSG00000121864 Zinc finger protein 639 3 179322991-179338583 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049023, HPA052163 Uncertain Supported Nucleoplasm Glioma:7.36e-5 (favourable), Liver cancer:2.13e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 69.0 Expressed in all +SLITRK3 KIAA0848 ENSG00000121871 SLIT and NTRK like family member 3 3 165186720-165197109 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017636, HPA048042 Enhanced Approved Mitochondria Tissue enriched Tissue enhanced cerebral cortex: 17.3;endometrium: 12.3 fallopian tube: 9.8 Cell line enhanced AF22: 2.6;HAP1: 2.3;SCLC-21H: 1.7 +PIK3CA PI3K ENSG00000121879 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 3 179148114-179240093 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA009985, CAB017804 Approved Approved Cytosol Expressed in all Mixed parathyroid gland: 23.8 Expressed in all +PDS5A KIAA0648, PIG54, SCC-112 ENSG00000121892 PDS5 cohesin associated factor A 4 39822863-39977956 Predicted intracellular proteins Evidence at protein level HPA036661, HPA036662 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 57.4 Expressed in all +TMEM156 FLJ23235 ENSG00000121895 Transmembrane protein 156 4 38966744-39032922 Predicted membrane proteins Evidence at transcript level Breast cancer:4.09e-4 (favourable) Mixed Group enriched 5 appendix: 11.8;lymph node: 27.8;spleen: 15.2;tonsil: 24.3;urinary bladder: 5.7 gallbladder: 3.0 Cell line enhanced Daudi: 28.3;HBEC3-KT: 59.6;hTERT-HME1: 48.9;PC-3: 34.1;U-698: 30.9 +LIAS LAS ENSG00000121897 Lipoic acid synthetase 4 39458587-39485109 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018842, HPA019076 Approved Approved Approved Nucleoplasm
Mitochondria Renal cancer:4.11e-7 (favourable) Expressed in all Mixed testis: 15.1 Expressed in all +CPXM2 CPX2, UNQ676 ENSG00000121898 Carboxypeptidase X, M14 family member 2 10 123706207-123940267 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048375 Uncertain Renal cancer:9.02e-4 (favourable) Expressed in all Tissue enhanced epididymis: 72.6;smooth muscle: 80.7 urinary bladder: 34.4 Group enriched 15 BJ: 15.4;fHDF/TERT166: 55.4 +TMEM54 CAC-1 ENSG00000121900 Transmembrane protein 54 1 32894594-32901438 Predicted membrane proteins Evidence at transcript level HPA061992 Approved Vesicles Liver cancer:3.08e-4 (unfavourable) Expressed in all Mixed colon: 222.7 Mixed +ZSCAN20 KOX29, ZNF31, ZNF360 ENSG00000121903 Zinc finger and SCAN domain containing 20 1 33472645-33496507 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA017933 Uncertain Approved Nucleoplasm Mixed Mixed parathyroid gland: 5.4 Mixed +CSMD2 KIAA1884 ENSG00000121904 CUB and Sushi multiple domains 2 1 33513999-34165842 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008622 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 2.6;gallbladder: 1.8 testis: 1.0 Cell line enhanced fHDF/TERT166: 5.3;HEL: 9.4;NTERA-2: 8.1;PC-3: 7.8;U-87 MG: 23.1 +HPCA ENSG00000121905 Hippocalcin 1 32885994-32898441 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012340, HPA043245 Supported Tissue enriched Tissue enriched 47 cerebral cortex: 153.0 testis: 3.2 Cell line enriched 8 SCLC-21H: 5.3 +LRIF1 C1orf103, FLJ11269, RIF1 ENSG00000121931 Ligand dependent nuclear receptor interacting factor 1 1 110947185-110964079 Predicted intracellular proteins Evidence at protein level HPA044515 Uncertain Supported Nucleus
Microtubule organizing center Ovarian cancer:1.73e-4 (favourable) Expressed in all Expressed in all testis: 46.8 Mixed +TMIGD3 AD026 ENSG00000121933 Transmembrane and immunoglobulin domain containing 3 1 111483348-111563962 Predicted membrane proteins Evidence at protein level Breast cancer:3.58e-4 (unfavourable) Tissue enriched Tissue enriched 15 testis: 99.0 placenta: 6.6 Cell line enhanced HDLM-2: 6.5;HMC-1: 1.5;NB-4: 2.4 +CLCC1 MCLC ENSG00000121940 Chloride channel CLIC like 1 1 108929508-108963457 Predicted membrane proteins, Transporters Evidence at protein level HPA009087, HPA013210 Enhanced Enhanced Endoplasmic reticulum Colorectal cancer:1.33e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 38.6 Expressed in all +GPSM2 DFNB82, LGN, Pins ENSG00000121957 G-protein signaling modulator 2 1 108875350-108934545 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007327, HPA008408, CAB018962 Uncertain Supported Cytosol Colorectal cancer:7.86e-5 (favourable), Renal cancer:3.02e-4 (unfavourable), Pancreatic cancer:5.89e-4 (unfavourable) Mixed Mixed skin: 49.3 Expressed in all +GTDC1 FLJ11753, Hmat-Xa ENSG00000121964 Glycosyltransferase like domain containing 1 2 143938068-144332568 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036694 Uncertain Approved Cytosol Renal cancer:6.60e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 29.4 Mixed +CXCR4 CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R ENSG00000121966 C-X-C motif chemokine receptor 4 2 136114349-136118165 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:1.41e-7 (unfavourable), Ovarian cancer:2.05e-4 (favourable), Stomach cancer:5.67e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 771.6 tonsil: 495.9 Cell line enhanced Daudi: 410.1;MOLT-4: 425.1;REH: 252.8;U-266/70: 489.0;U-698: 459.8 +ZRANB3 DKFZP434B1727 ENSG00000121988 Zinc finger RANBP2-type containing 3 2 135136916-135531236 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA035234 Supported Nucleus Mixed Mixed testis: 8.6 Expressed in all +ACVR2A ACTRII, ACVR2 ENSG00000121989 Activin A receptor type 2A 2 147844517-147930826 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level HPA046997 Approved Approved Cytosol Renal cancer:1.62e-4 (favourable) Expressed in all Mixed skin: 22.5 Mixed +POLK DINB1, DINP, POLQ ENSG00000122008 DNA polymerase kappa 5 75511756-75601144 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012035, HPA057303, HPA068117, HPA069375 Enhanced Nucleoplasm
Nuclear bodies Expressed in all Mixed thyroid gland: 12.8 Mixed +SV2C ENSG00000122012 Synaptic vesicle glycoprotein 2C 5 76083172-76353939 Predicted membrane proteins Evidence at protein level HPA040722, HPA040770 Supported Supported Nucleoplasm
Vesicles Not detected Tissue enhanced adrenal gland: 1.6;cerebral cortex: 3.4 fallopian tube,ovary: 0.6 Cell line enhanced Karpas-707: 6.5;SCLC-21H: 4.3;SH-SY5Y: 9.0 +FLT3 CD135, FLK2, STK1 ENSG00000122025 Fms related tyrosine kinase 3 13 28003274-28100592 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA047539 Approved Endoplasmic reticulum Tissue enhanced Tissue enhanced lymph node: 7.0;spleen: 7.7 appendix: 3.9 Group enriched 14 REH: 38.7;THP-1: 17.4 +RPL21 DKFZp686C06101, FLJ27458, L21, MGC104274, MGC104275, MGC71252 ENSG00000122026 Ribosomal protein L21 13 27251309-27256691 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047252 Approved Supported Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Melanoma:6.66e-4 (unfavourable) Expressed in all Expressed in all ovary: 2382.8 Expressed in all +MTIF3 IF-3mt, IF3(mt) ENSG00000122033 Mitochondrial translational initiation factor 3 13 27435643-27450591 Predicted intracellular proteins Evidence at protein level HPA039791 Approved Supported Nucleoplasm
Mitochondria Urothelial cancer:8.41e-4 (favourable) Expressed in all Expressed in all testis: 101.3 Expressed in all +GTF3A AP2, TFIIIA ENSG00000122034 General transcription factor IIIA 13 27424544-27435823 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007990 Supported Supported Nucleus Renal cancer:3.43e-6 (unfavourable) Expressed in all Expressed in all lymph node: 122.3 Expressed in all +RASL11A ENSG00000122035 RAS like family 11 member A 13 27270327-27273690 Predicted intracellular proteins Evidence at protein level HPA004859, HPA053296 Supported Approved Nuclear bodies Renal cancer:3.52e-4 (unfavourable), Lung cancer:5.43e-4 (favourable) Expressed in all Mixed rectum: 25.0 Cell line enhanced ASC diff: 56.5;PC-3: 18.3 +UBL3 DKFZP434K151, FLJ32018, HCG-1, PNSC1 ENSG00000122042 Ubiquitin like 3 13 29764371-29850684 Predicted intracellular proteins Evidence at protein level HPA053772, HPA058781 Uncertain Approved Centrosome Renal cancer:4.23e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 90.6 Expressed in all +FYTTD1 DKFZp761B1514, UIF ENSG00000122068 Forty-two-three domain containing 1 3 197737179-197787596 Predicted intracellular proteins Evidence at protein level HPA054474 Supported Nuclear speckles Endometrial cancer:3.08e-4 (unfavourable) Expressed in all Expressed in all testis: 76.4 Expressed in all +MTERF4 MGC61716, MTERFD2 ENSG00000122085 Mitochondrial transcription termination factor 4 2 241072169-241102332 Predicted intracellular proteins Evidence at protein level HPA027097 Uncertain Supported Mitochondria
Cytosol Pancreatic cancer:3.48e-4 (favourable) Expressed in all Expressed in all thyroid gland: 58.3 Expressed in all +XPNPEP2 ENSG00000122121 X-prolyl aminopeptidase 2 X 129738974-129769538 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA000339, CAB025136, CAB025269 Enhanced Group enriched Group enriched 12 duodenum: 128.1;kidney: 175.9;small intestine: 231.5 liver: 14.3 Cell line enhanced ASC diff: 6.9;ASC TERT1: 36.6;HSkMC: 19.4 +SASH3 753P9, CXorf9, HACS2, SH3D6C, SLY ENSG00000122122 SAM and SH3 domain containing 3 X 129779979-129795201 Predicted intracellular proteins Evidence at protein level HPA001085 Enhanced Approved Plasma membrane Renal cancer:6.51e-5 (unfavourable), Endometrial cancer:3.15e-4 (favourable) Expressed in all Tissue enhanced lymph node: 136.7;spleen: 99.3;tonsil: 97.4 appendix: 80.4 Cell line enhanced Daudi: 116.3;MOLT-4: 95.0;NB-4: 56.4;REH: 79.9;U-698: 101.7;U-937: 90.0 +OCRL OCRL1 ENSG00000122126 OCRL, inositol polyphosphate-5-phosphatase X 129539849-129592561 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA012495 Approved Approved Microtubules
Cytosol Breast cancer:2.93e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 65.3 Mixed +PAEP GD, GdA, GdF, GdS, MGC138509, MGC142288, PAEG, PEP, PP14 ENSG00000122133 Progestagen associated endometrial protein 9 135561756-135566955 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016762, HPA020108, HPA029473 Enhanced Renal cancer:0.00e+0 (unfavourable), Liver cancer:6.61e-6 (unfavourable), Stomach cancer:5.46e-4 (unfavourable) Tissue enriched Tissue enriched 7 endometrium: 437.0 seminal vesicle: 61.5 Cell line enriched 6 SK-MEL-30: 16.7 +OBP2A hOBPIIa, LCN13, OBP ENSG00000122136 Odorant binding protein 2A 9 135546139-135549969 Predicted secreted proteins Evidence at protein level HPA055955 Uncertain Tissue enriched Group enriched 19 fallopian tube: 35.5;testis: 7.6 skin: 1.1 Group enriched 8 U-266/70: 1.0;U-266/84: 3.7 +MRPS2 CGI-91 ENSG00000122140 Mitochondrial ribosomal protein S2 9 135499984-135504673 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA029487, HPA057261 Approved Supported Mitochondria Renal cancer:6.96e-9 (favourable) Expressed in all Expressed in all fallopian tube: 55.1 Expressed in all +TBX22 CLPA, CPX ENSG00000122145 T-box 22 X 80014756-80031769 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Group enriched 19 testis: 10.4;thyroid gland: 3.5 seminal vesicle: 0.3 Cell line enriched 6 HDLM-2: 1.6 +FMOD SLRR2E ENSG00000122176 Fibromodulin 1 203340628-203351489 Predicted secreted proteins Evidence at protein level Renal cancer:1.40e-5 (unfavourable), Urothelial cancer:2.67e-4 (unfavourable) Expressed in all Mixed gallbladder: 171.7 Cell line enhanced CACO-2: 28.0;HHSteC: 8.7;HSkMC: 14.1 +MYOG bHLHc3, MYF4 ENSG00000122180 Myogenin 1 203083132-203086036 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028336, HPA038093 Approved Supported Nucleoplasm Group enriched Tissue enriched 9 skeletal muscle: 31.7 prostate: 3.3 Group enriched 197 HSkMC: 21.2;RH-30: 55.2 +LAX1 FLJ20340, LAX ENSG00000122188 Lymphocyte transmembrane adaptor 1 1 203765176-203776233 Predicted membrane proteins Evidence at protein level HPA002461, HPA003887, CAB025358 Enhanced Enhanced Golgi apparatus
Plasma membrane
Cytosol Mixed Tissue enhanced tonsil: 15.3 lymph node: 10.3 Cell line enhanced Karpas-707: 14.1;U-266/70: 18.2;U-266/84: 40.4;U-698: 14.6 +PLG ENSG00000122194 Plasminogen 6 160702238-160753315 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000668, CAB016678, HPA021602, HPA048823, HPA053770 Supported Uncertain Vesicles Renal cancer:4.22e-4 (favourable) Tissue enriched Tissue enriched 6 liver: 1749.3 kidney: 313.4 Cell line enhanced RH-30: 1.0 +KIAA1191 FLJ21022, p33MONOX ENSG00000122203 KIAA1191 5 176346061-176361968 Predicted intracellular proteins Evidence at protein level HPA044701, HPA048145 Uncertain Approved Nucleoplasm Renal cancer:9.94e-5 (favourable) Expressed in all Expressed in all kidney: 198.3 Expressed in all +COPA HEP-COP ENSG00000122218 Coatomer protein complex subunit alpha 1 160289273-160343400 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028024 Supported Approved Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:1.08e-4 (unfavourable), Cervical cancer:6.54e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 118.9 Expressed in all +CD244 2B4, NAIL, NKR2B4, Nmrk, SLAMF4 ENSG00000122223 CD244 molecule 1 160830160-160862855 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced spleen: 23.5 bone marrow: 6.2 Cell line enhanced HEL: 18.7;HMC-1: 61.7;U-937: 22.7 +LY9 CD229, hly9, mLY9, SLAMF3 ENSG00000122224 Lymphocyte antigen 9 1 160796074-160828261 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050917 Approved Mixed Tissue enhanced lymph node: 34.5;spleen: 28.2;tonsil: 28.3 appendix: 17.8 Cell line enhanced Daudi: 10.2;Karpas-707: 20.1;U-266/70: 53.8;U-266/84: 20.4 +HS3ST2 3OST2 ENSG00000122254 Heparan sulfate-glucosamine 3-sulfotransferase 2 16 22814177-22916338 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017736 Approved Renal cancer:1.35e-4 (favourable), Glioma:2.22e-4 (unfavourable) Mixed Tissue enriched 30 cerebral cortex: 35.7 lung: 1.1 Group enriched 7 HaCaT: 8.5;SH-SY5Y: 17.7 +RBBP6 P2P-R, PACT, SNAMA ENSG00000122257 RB binding protein 6, ubiquitin ligase 16 24537693-24572863 Enzymes, Predicted intracellular proteins Evidence at protein level CAB032866, HPA041725, HPA043544 Approved Enhanced Nuclear speckles Expressed in all Expressed in all bone marrow: 91.5 Expressed in all +ZC3H7A FLJ20318, HSPC055, ZC3H7, ZC3HDC7 ENSG00000122299 Zinc finger CCCH-type containing 7A 16 11750586-11797267 Predicted intracellular proteins Evidence at protein level HPA040808, HPA059849 Uncertain Supported Cytosol Expressed in all Expressed in all parathyroid gland: 47.0 Expressed in all +PRM2 CT94.2 ENSG00000122304 Protamine 2 16 11275639-11276480 Predicted intracellular proteins Evidence at protein level CAB032738, HPA056386 Enhanced Tissue enriched Tissue enriched 5145 testis: 7760.7 small intestine: 1.5 Cell line enhanced BEWO: 1.1;U-2197: 1.7 +SERAC1 FLJ14917 ENSG00000122335 Serine active site containing 1 6 158109515-158168270 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA025715, HPA025716 Enhanced Expressed in all Expressed in all testis: 16.5 Expressed in all +ANXA11 ANX11 ENSG00000122359 Annexin A11 10 80150889-80205572 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004851, HPA027545 Supported Supported Nucleoplasm
Cytosol Renal cancer:6.69e-8 (favourable) Expressed in all Expressed in all esophagus: 203.1 Expressed in all +LDB3 CMD1C, KIAA0613, PDLIM6, ZASP ENSG00000122367 LIM domain binding 3 10 86668449-86736068 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048955 Enhanced Supported Nucleoplasm
Focal adhesion sites
Cytosol Mixed Group enriched 13 heart muscle: 568.8;skeletal muscle: 1039.8 prostate: 60.3 Cell line enhanced HSkMC: 2.3;SCLC-21H: 6.3;SK-MEL-30: 2.1 +OPN4 melanopsin, MOP ENSG00000122375 Opsin 4 10 86654557-86666848 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA039147 Approved Not detected Tissue enhanced cerebral cortex: 2.2;parathyroid gland: 1.4 skeletal muscle: 0.9 Not detected +FAM35A bA163M19.1, FAM35A1, MGC5560 ENSG00000122376 Family with sequence similarity 35 member A 10 87094161-87191468 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036582 Uncertain Approved Nucleoplasm
Actin filaments Glioma:5.44e-4 (favourable), Colorectal cancer:6.06e-4 (favourable) Expressed in all Expressed in all thyroid gland: 38.8 Expressed in all +FAM213A Adrx, C10orf58, MGC4248, PAMM ENSG00000122378 Family with sequence similarity 213 member A 10 80407829-80437115 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009025, HPA024565 Approved Urothelial cancer:6.11e-4 (favourable) Expressed in all Expressed in all adipose tissue: 425.0 Cell line enhanced ASC diff: 650.7;HUVEC TERT2: 365.0 +ZNF205 Zfp13, ZNF210 ENSG00000122386 Zinc finger protein 205 16 3112560-3120517 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001791 Uncertain Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 14.6 Mixed +NAA60 FLJ14154, NAT15 ENSG00000122390 N(alpha)-acetyltransferase 60, NatF catalytic subunit 16 3443611-3486963 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040916 Approved Uncertain Actin filaments
Cytosol Endometrial cancer:3.14e-4 (favourable), Pancreatic cancer:4.30e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 86.3 Expressed in all +RPL5 L5, PPP1R135 ENSG00000122406 Ribosomal protein L5 1 92832025-92841924 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043717, HPA054444 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:6.81e-5 (unfavourable) Expressed in all Expressed in all ovary: 4042.9 Expressed in all +ODF2L KIAA1229 ENSG00000122417 Outer dense fiber of sperm tails 2 like 1 86346824-86396342 Predicted intracellular proteins Evidence at protein level HPA028020, HPA028095, HPA028333 Uncertain Approved Mitochondria Renal cancer:4.69e-7 (unfavourable) Mixed Expressed in all fallopian tube: 34.3 Mixed +PTGFR FP ENSG00000122420 Prostaglandin F receptor 1 78303884-78539749 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced endometrium: 30.5;smooth muscle: 25.7 urinary bladder: 12.9 Group enriched 7 ASC TERT1: 193.6;HSkMC: 63.3 +SPATA1 SP-2 ENSG00000122432 Spermatogenesis associated 1 1 84506300-84566194 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 8 testis: 4.5 skin: 0.5 Not detected +TRMT13 CCDC76, FLJ10287, FLJ11219 ENSG00000122435 TRNA methyltransferase 13 homolog 1 100133150-100150497 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028494 Approved Approved Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Renal cancer:6.89e-6 (unfavourable), Liver cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.5 Expressed in all +LRRC39 MGC14816 ENSG00000122477 Leucine rich repeat containing 39 1 100148449-100178273 Predicted intracellular proteins Evidence at protein level HPA077159 Enhanced Mixed Group enriched 10 heart muscle: 81.3;skeletal muscle: 175.6 testis: 12.3 Cell line enhanced SK-MEL-30: 5.8 +RWDD3 DKFZP566K023 ENSG00000122481 RWD domain containing 3 1 95234155-95247225 Predicted intracellular proteins Evidence at protein level Renal cancer:6.46e-8 (unfavourable), Urothelial cancer:2.06e-4 (favourable) Expressed in all Mixed endometrium,fallopian tube: 14.6 Expressed in all +ZNF644 BM-005, KIAA1221, MGC60165, MGC70410 ENSG00000122482 Zinc finger protein 644 1 90915298-91022272 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057795 Uncertain Uncertain Vesicles Colorectal cancer:4.27e-4 (favourable), Endometrial cancer:8.39e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 31.0 Expressed in all +CCDC18 NY-SAR-41 ENSG00000122483 Coiled-coil domain containing 18 1 93179919-93278730 Predicted intracellular proteins Evidence at protein level HPA028035 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced testis: 17.2 lymph node: 10.7 Mixed +RPAP2 C1orf82, FLJ13150, Rtr1 ENSG00000122484 RNA polymerase II associated protein 2 1 92298965-92402056 Enzymes, Predicted membrane proteins Evidence at protein level HPA046443 Approved Supported Nucleoli
Cytosol Expressed in all Mixed thyroid gland: 4.8 Expressed in all +PQLC1 FLJ22378 ENSG00000122490 PQ loop repeat containing 1 18 79902420-79951664 Predicted membrane proteins Evidence at protein level HPA051666 Uncertain Approved Nucleoplasm Expressed in all Expressed in all adipose tissue: 40.6 Expressed in all +BBS9 B1, PTHB1 ENSG00000122507 Bardet-Biedl syndrome 9 7 33129244-33606068 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021289 Uncertain Renal cancer:1.86e-4 (favourable) Expressed in all Mixed testis: 24.0 Expressed in all +PMS2 H_DJ0042M02.9, HNPCC4, MLH4, PMSL2 ENSG00000122512 PMS1 homolog 2, mismatch repair system component 7 5973239-6009125 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB010235, HPA044400, HPA066490, HPA070310 Approved Enhanced Nucleoplasm
Cytosol Renal cancer:1.23e-5 (favourable) Expressed in all Mixed parathyroid gland: 20.2 Expressed in all +ZMIZ2 DKFZp761I2123, hZIMP7, KIAA1886, NET27, ZIMP7 ENSG00000122515 Zinc finger MIZ-type containing 2 7 44748581-44769881 Predicted intracellular proteins Evidence at protein level HPA040716 Supported Supported Nucleoplasm Liver cancer:6.82e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 40.7 Expressed in all +OCM OCM1 ENSG00000122543 Oncomodulin 7 5879827-5886362 Predicted intracellular proteins Evidence at protein level HPA046422 Uncertain Not detected Tissue enhanced lymph node: 2.4 testis: 1.5 Not detected +SEPT7 CDC10, CDC3, SEPT7A ENSG00000122545 Septin 7 7 35800932-35907105 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023309, HPA029524 Enhanced Enhanced Nucleoli
Actin filaments
Midbody Liver cancer:2.37e-4 (unfavourable), Renal cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 430.4 Expressed in all +EEPD1 KIAA1706 ENSG00000122547 Endonuclease/exonuclease/phosphatase family domain containing 1 7 36153149-36301543 Predicted intracellular proteins Evidence at protein level HPA053668 Approved Nuclear speckles
Vesicles
Plasma membrane Expressed in all Expressed in all cerebral cortex: 27.1 Cell line enhanced HDLM-2: 16.9;PC-3: 20.8 +KLHL7 KLHL6, RP42, SBBI26 ENSG00000122550 Kelch like family member 7 7 23105758-23177914 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029491, HPA029492 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:8.98e-5 (favourable), Liver cancer:7.96e-4 (unfavourable) Expressed in all Expressed in all testis: 76.1 Expressed in all +HERPUD2 FLJ22313 ENSG00000122557 HERPUD family member 2 7 35632659-35695571 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015630, HPA076087 Approved Approved Nucleoli Expressed in all Expressed in all testis: 48.2 Expressed in all +CBX3 HP1Hs-gamma ENSG00000122565 Chromobox 3 7 26201162-26213356 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001973, HPA004902 Enhanced Supported Nucleus
Nuclear bodies Liver cancer:2.20e-8 (unfavourable), Renal cancer:4.56e-7 (unfavourable), Pancreatic cancer:4.00e-4 (unfavourable), Breast cancer:7.92e-4 (unfavourable) Expressed in all Expressed in all testis: 201.3 Expressed in all +HNRNPA2B1 HNRPA2B1 ENSG00000122566 Heterogeneous nuclear ribonucleoprotein A2/B1 7 26189927-26201529 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001666, HPA005812, CAB012403, HPA065537 Supported Enhanced Nucleoplasm Liver cancer:1.03e-6 (unfavourable), Renal cancer:8.01e-5 (unfavourable), Prostate cancer:5.12e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 753.7 Expressed in all +WIPF3 CR16, FLJ36931 ENSG00000122574 WAS/WASL interacting protein family member 3 7 29806486-29917066 Predicted intracellular proteins Evidence at protein level HPA041145, HPA041211 Uncertain Uncertain Mitochondria Breast cancer:7.93e-4 (favourable) Mixed Tissue enhanced ovary: 52.8;testis: 37.3 epididymis: 25.0 Cell line enhanced HAP1: 19.3;K-562: 6.0;NTERA-2: 5.3;RPMI-8226: 8.0 +NXPH1 ENSG00000122584 Neurexophilin 1 7 8433955-8752963 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA020062 Uncertain Group enriched Group enriched 81 adrenal gland: 52.1;cerebral cortex: 47.2 breast: 0.6 Cell line enhanced Karpas-707: 7.7;SCLC-21H: 1.3;WM-115: 3.3 +NPY PYY4 ENSG00000122585 Neuropeptide Y 7 24284163-24291865 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB016733, CAB034368, HPA036636, HPA044572, HPA056798 Supported Supported Enhanced Golgi apparatus Endometrial cancer:5.78e-4 (unfavourable) Tissue enriched Group enriched 18 adrenal gland: 153.2;cerebral cortex: 211.6;prostate: 495.0 appendix: 16.1 Cell line enriched 39 SH-SY5Y: 696.9 +FAM126A DRCTNNB1A, HCC, HYCC1, hyccin ENSG00000122591 Family with sequence similarity 126 member A 7 22889371-23014130 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042873 Approved Supported Plasma membrane
Cytosol Renal cancer:6.04e-7 (unfavourable), Stomach cancer:5.99e-4 (unfavourable), Urothelial cancer:9.03e-4 (unfavourable) Expressed in all Expressed in all testis: 33.4 Mixed +HOXA7 HOX1, HOX1A ENSG00000122592 Homeobox A7 7 27153716-27157936 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA074048 Approved Nucleoplasm
Nuclear membrane Renal cancer:1.15e-5 (favourable), Endometrial cancer:7.87e-5 (unfavourable) Mixed Mixed epididymis: 21.6 Cell line enhanced HAP1: 38.0;RPTEC TERT1: 34.0;SCLC-21H: 42.6 +INHBA ENSG00000122641 Inhibin beta A subunit 7 41667168-41705834 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:7.91e-8 (unfavourable), Cervical cancer:1.46e-5 (unfavourable), Head and neck cancer:4.34e-4 (unfavourable), Lung cancer:7.72e-4 (unfavourable) Expressed in all Tissue enhanced endometrium: 28.7;gallbladder: 35.1 lung: 16.4 Group enriched 6 HBEC3-KT: 54.3;hTEC/SVTERT24-B: 227.2;hTERT-HME1: 71.4;TIME: 97.6;U-138 MG: 172.4;U-2 OS: 52.9 +FKBP9 FKBP60, FKBP63 ENSG00000122642 FK506 binding protein 9 7 32957404-33006931 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012595, HPA055256 Approved Supported Golgi apparatus
Vesicles
Mitochondria Urothelial cancer:7.02e-6 (unfavourable), Head and neck cancer:2.02e-4 (unfavourable), Cervical cancer:4.22e-4 (unfavourable), Glioma:8.06e-4 (unfavourable), Liver cancer:8.69e-4 (unfavourable) Expressed in all Expressed in all placenta: 110.4 Mixed +NT5C3A cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1 ENSG00000122643 5'-nucleotidase, cytosolic IIIA 7 33014114-33062797 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA010630, HPA029058 Uncertain Renal cancer:1.70e-4 (unfavourable), Liver cancer:2.42e-4 (unfavourable) Expressed in all Expressed in all rectum: 46.5 Expressed in all +ARL4A ARL4 ENSG00000122644 ADP ribosylation factor like GTPase 4A 7 12686856-12690934 Predicted intracellular proteins Evidence at protein level HPA064513 Supported Nucleoplasm
Cytosol Expressed in all Tissue enhanced testis: 313.8 skin: 79.3 Cell line enhanced AN3-CA: 241.9;K-562: 291.3 +CCZ1 C7orf28A, CCZ1A, CGI-43 ENSG00000122674 CCZ1 homolog, vacuolar protein trafficking and biogenesis associated 7 5898725-5926550 Predicted intracellular proteins Evidence at protein level HPA045114, HPA050006 Uncertain Enhanced Vesicles Expressed in all Expressed in all parathyroid gland: 77.0 Expressed in all +POLM Tdt-N ENSG00000122678 DNA polymerase mu 7 44072247-44082540 Enzymes, Predicted intracellular proteins Evidence at protein level HPA058900, HPA066007 Supported Nucleus Expressed in all Expressed in all spleen: 10.9 Cell line enhanced HBEC3-KT: 47.1 +RAMP3 ENSG00000122679 Receptor activity modifying protein 3 7 45157791-45186302 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Liver cancer:2.50e-6 (favourable), Cervical cancer:2.89e-4 (favourable) Expressed in all Tissue enhanced lung: 120.2 thyroid gland: 66.3 Cell line enhanced Karpas-707: 1.8 +MRM2 FJH1, FTSJ2, RRMJ2 ENSG00000122687 Mitochondrial rRNA methyltransferase 2 7 2234231-2242198 Predicted intracellular proteins Evidence at protein level HPA019826, HPA049622 Uncertain Liver cancer:5.21e-6 (unfavourable) Expressed in all Expressed in all lymph node: 19.6 Expressed in all +TWIST1 ACS3, bHLHa38, BPES2, BPES3, CRS, CRS1, H-twist, SCS, TWIST ENSG00000122691 Twist family bHLH transcription factor 1 7 19020991-19117672 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Tissue enhanced adipose tissue: 22.7;endometrium: 30.7 placenta: 17.3 Cell line enriched 6 SH-SY5Y: 272.1 +SMU1 BWD, FLJ10805, fSAP57, SMU-1 ENSG00000122692 DNA replication regulator and spliceosomal factor 9 33041764-33076659 Predicted intracellular proteins Evidence at protein level HPA019228, HPA019708 Supported Approved Vesicles Renal cancer:1.67e-5 (favourable), Ovarian cancer:1.25e-4 (favourable), Cervical cancer:2.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.4 Expressed in all +GLIPR2 C9orf19, GAPR-1 ENSG00000122694 GLI pathogenesis related 2 9 36136536-36163913 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029478 Approved Uncertain Vesicles
Microtubules Renal cancer:6.54e-7 (unfavourable) Expressed in all Expressed in all lung: 93.6 Cell line enhanced TIME: 103.7 +SLC25A51 CG7943, MCART1, MGC14836 ENSG00000122696 Solute carrier family 25 member 51 9 37879400-37904353 Predicted membrane proteins, Transporters Evidence at protein level HPA046388, HPA058261 Uncertain Approved Mitochondria Liver cancer:5.67e-5 (unfavourable), Renal cancer:1.52e-4 (favourable), Thyroid cancer:2.21e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 15.4 Expressed in all +CLTA Lca ENSG00000122705 Clathrin light chain A 9 36190856-36304781 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002665, HPA050918, HPA054667 Enhanced Enhanced Vesicles
Endosomes
Lysosomes Liver cancer:9.46e-5 (unfavourable), Thyroid cancer:1.01e-4 (favourable), Breast cancer:5.64e-4 (favourable) Expressed in all Expressed in all placenta: 178.0 Expressed in all +RECK hRECK, ST15 ENSG00000122707 Reversion inducing cysteine rich protein with kazal motifs 9 36036433-36124451 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB025109, HPA071729 Supported Supported Plasma membrane Stomach cancer:7.31e-4 (unfavourable) Expressed in all Mixed endometrium: 21.4 Group enriched 5 ASC diff: 122.8;ASC TERT1: 99.6;BJ: 49.1;BJ hTERT+: 67.5;fHDF/TERT166: 40.1;HSkMC: 46.5;TIME: 32.3 +SPINK4 MGC133107, PEC-60 ENSG00000122711 Serine peptidase inhibitor, Kazal type 4 9 33218365-33248567 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007286 Enhanced Approved Nucleus
Golgi apparatus
Vesicles Colorectal cancer:8.85e-5 (favourable) Group enriched Group enriched 6 colon: 631.8;duodenum: 266.4;rectum: 1071.3;small intestine: 734.5 appendix: 107.1 Cell line enriched 8 HMC-1: 152.9 +TAF1L ENSG00000122728 TATA-box binding protein associated factor 1 like 9 32629454-32635669 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056605 Uncertain Not detected Tissue enriched 31 testis: 3.0 all non-specific tissues: 0.0 Not detected +ACO1 IREB1, IREBP, IRP1 ENSG00000122729 Aconitase 1 9 32384603-32454769 Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019371, HPA024157 Enhanced Supported Mitochondria
Cytosol Renal cancer:5.73e-5 (favourable) Expressed in all Expressed in all adipose tissue: 105.1 Expressed in all +PHF24 KIAA1045 ENSG00000122733 PHD finger protein 24 9 34957608-34982544 Predicted intracellular proteins Evidence at protein level HPA020974 Approved Tissue enhanced Group enriched 36 cerebral cortex: 58.6;testis: 25.9 skin: 1.1 Cell line enhanced WM-115: 1.1 +DNAI1 CILD1, DIC1, PCD ENSG00000122735 Dynein axonemal intermediate chain 1 9 34457414-34520989 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021649, HPA021843 Enhanced Tissue enhanced Group enriched 10 fallopian tube: 54.3;testis: 61.2 lung: 5.6 Cell line enhanced BEWO: 1.9;HDLM-2: 1.3 +DCAF10 FLJ23201, MGC10765, WDR32 ENSG00000122741 DDB1 and CUL4 associated factor 10 9 37800502-37867666 Predicted intracellular proteins Evidence at protein level HPA024160 Uncertain Approved Nucleoli fibrillar center Renal cancer:1.02e-6 (favourable) Expressed in all Expressed in all testis: 36.0 Expressed in all +CNTFR ENSG00000122756 Ciliary neurotrophic factor receptor 9 34551432-34590140 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025310 Approved Tissue enhanced Tissue enhanced adipose tissue: 62.6;cerebral cortex: 53.4 spleen: 27.5 Group enriched 9 AF22: 107.8;SH-SY5Y: 55.3 +KIAA1549 ENSG00000122778 KIAA1549 7 138831381-138981318 Cancer-related genes, Disease related genes, Predicted membrane proteins Evidence at protein level HPA019560 Approved Approved Nuclear membrane
Intermediate filaments Renal cancer:3.93e-7 (favourable) Mixed Mixed seminal vesicle: 10.5 Cell line enhanced SH-SY5Y: 29.9 +TRIM24 hTIF1, RNF82, TIF1, Tif1a ENSG00000122779 Tripartite motif containing 24 7 138460334-138589993 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA043495, HPA061717 Approved Enhanced Nucleoplasm Lung cancer:6.57e-4 (favourable), Liver cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all testis: 49.6 Expressed in all +C7orf49 FLJ22450, FLJ27285, MGC5242, MRI, MRI-2 ENSG00000122783 Chromosome 7 open reading frame 49 7 135092363-135170795 Predicted intracellular proteins Evidence at protein level HPA020060 Approved Approved Golgi apparatus Liver cancer:2.52e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.6 Expressed in all +CALD1 CDM, H-CAD, L-CAD ENSG00000122786 Caldesmon 1 7 134744252-134970728 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000006, HPA008066, HPA017330 Enhanced Enhanced Plasma membrane
Actin filaments Renal cancer:1.84e-5 (unfavourable), Melanoma:3.73e-4 (unfavourable) Expressed in all Tissue enhanced seminal vesicle: 1289.8 smooth muscle: 1185.8 Cell line enhanced fHDF/TERT166: 910.7 +AKR1D1 SRD5B1 ENSG00000122787 Aldo-keto reductase family 1 member D1 7 138002324-138117986 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA057002 Enhanced Approved Nucleoplasm
Cytosol Liver cancer:9.91e-5 (favourable) Tissue enriched Tissue enriched 31 liver: 229.4 breast: 7.2 Cell line enriched 16 Hep G2: 8.6 +NUDT10 DIPP3a, hDIPP3alpha ENSG00000122824 Nudix hydrolase 10 X 51332231-51337525 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047027, HPA057684 Approved Approved Cytosol Group enriched Tissue enhanced testis: 49.7 prostate: 24.8 Group enriched 8 AF22: 7.4;HAP1: 14.7;HEK 293: 9.7;NTERA-2: 25.9;SH-SY5Y: 6.0;U-2 OS: 13.4 +SFTPA1 COLEC4, SFTP1, SP-A, SP-A1 ENSG00000122852 Surfactant protein A1 10 79610939-79615455 Disease related genes, Predicted secreted proteins Evidence at protein level CAB016793, HPA042638, HPA045752, HPA049368 Supported Tissue enriched Tissue enriched 1180 lung: 10513.5 adrenal gland: 8.9 Group enriched 6 RPMI-8226: 29.9;U-2197: 6.8 +NEUROG3 Atoh5, bHLHa7, Math4B, ngn3 ENSG00000122859 Neurogenin 3 10 69571698-69573238 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA039785 Uncertain Tissue enhanced Tissue enhanced duodenum: 2.8;small intestine: 1.3 colon,rectum: 0.4 Group enriched 19 HMC-1: 1.7;THP-1: 7.1 +PLAU UPA, URK ENSG00000122861 Plasminogen activator, urokinase 10 73909177-73917497 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008719 Approved Pancreatic cancer:1.32e-4 (unfavourable), Head and neck cancer:2.70e-4 (unfavourable), Endometrial cancer:3.38e-4 (favourable), Renal cancer:3.51e-4 (unfavourable), Lung cancer:4.04e-4 (unfavourable) Expressed in all Expressed in all appendix: 60.3 Cell line enhanced CAPAN-2: 757.8;LHCN-M2: 690.9;RPTEC TERT1: 2356.8;U-251 MG: 715.9 +SRGN PPG, PRG, PRG1 ENSG00000122862 Serglycin 10 69088106-69104811 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA000759 Enhanced Renal cancer:3.18e-5 (unfavourable) Expressed in all Group enriched 6 appendix: 1121.8;bone marrow: 5139.0 gallbladder: 509.4 Cell line enhanced HL-60: 3514.5;THP-1: 2938.4;TIME: 2120.9;U-937: 2758.4 +CHST3 C6ST, C6ST1 ENSG00000122863 Carbohydrate sulfotransferase 3 10 71964365-72013564 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA047523, HPA055704 Enhanced Approved Golgi apparatus
Cytosol Expressed in all Mixed testis: 30.7 Mixed +BICC1 ENSG00000122870 BicC family RNA binding protein 1 10 58513140-58831437 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045212 Enhanced Approved Nucleoplasm Expressed in all Tissue enhanced kidney: 32.0 gallbladder: 19.2 Cell line enhanced CACO-2: 79.9;RPTEC TERT1: 112.1 +CISD1 C10orf70, MDS029, mitoNEET, ZCD1 ENSG00000122873 CDGSH iron sulfur domain 1 10 58269058-58289586 Predicted membrane proteins Evidence at protein level HPA074383 Supported Mitochondria Breast cancer:1.11e-4 (unfavourable), Liver cancer:4.15e-4 (unfavourable), Urothelial cancer:6.69e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 118.3 cerebral cortex: 27.2 Expressed in all +EGR2 KROX20 ENSG00000122877 Early growth response 2 10 62811996-62919900 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031165 Supported Nucleoplasm Breast cancer:7.30e-5 (favourable) Expressed in all Tissue enhanced thyroid gland: 234.3 epididymis: 73.8 Cell line enriched 7 U-87 MG: 22.2 +ECD GCR2, hSGT1 ENSG00000122882 Ecdysoneless cell cycle regulator 10 73130155-73169055 Predicted intracellular proteins Evidence at protein level HPA006465 Approved Supported Nucleoplasm
Cytosol Liver cancer:6.87e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 38.3 Expressed in all +P4HA1 C-P4Halpha(I), P4HA ENSG00000122884 Prolyl 4-hydroxylase subunit alpha 1 10 73007217-73096974 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA007599, HPA026593 Enhanced Supported Endoplasmic reticulum
Vesicles
Mitochondria Renal cancer:9.40e-9 (unfavourable), Head and neck cancer:1.19e-5 (unfavourable), Cervical cancer:3.19e-5 (unfavourable), Pancreatic cancer:2.85e-4 (unfavourable), Lung cancer:5.10e-4 (unfavourable), Breast cancer:9.01e-4 (unfavourable) Expressed in all Expressed in all placenta: 91.7 Expressed in all +SLC25A16 D10S105E, GDA, HGT.1, ML7 ENSG00000122912 Solute carrier family 25 member 16 10 68477999-68527474 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA036243, HPA044580 Uncertain Approved Mitochondria Expressed in all Mixed prostate: 13.4 Mixed +ZWINT KNTC2AP, SIP30, Zwint1 ENSG00000122952 ZW10 interacting kinetochore protein 10 56357228-56361275 Predicted intracellular proteins Evidence at protein level HPA005757, HPA022264, CAB033926 Enhanced Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:3.72e-12 (unfavourable), Liver cancer:1.77e-8 (unfavourable) Expressed in all Mixed testis: 47.7 Mixed +VPS26A Hbeta58, PEP8A, VPS26 ENSG00000122958 VPS26, retromer complex component A 10 69123512-69172861 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011602, HPA057498, CAB075733 Enhanced Enhanced Endosomes
Lysosomes Liver cancer:1.70e-6 (unfavourable), Pancreatic cancer:9.18e-6 (unfavourable), Head and neck cancer:1.72e-4 (unfavourable) Expressed in all Expressed in all testis: 86.8 Expressed in all +RBM19 DKFZp586F1023, KIAA0682 ENSG00000122965 RNA binding motif protein 19 12 113816738-113966371 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038860, HPA058732 Supported Supported Nucleoli Liver cancer:5.87e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 19.6 Expressed in all +CIT CITK, CRIK, KIAA0949, STK21 ENSG00000122966 Citron rho-interacting serine/threonine kinase 12 119685790-119877291 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019082, HPA048812, HPA075506 Uncertain Approved Cytosol Mixed Mixed cerebral cortex: 10.4 Mixed +IFT81 CDV-1R, CDV1, MGC4027 ENSG00000122970 Intraflagellar transport 81 12 110124335-110218797 Predicted intracellular proteins Evidence at protein level HPA019087, HPA020051 Enhanced Approved Centrosome
Cytosol Expressed in all Mixed testis: 58.0 Expressed in all +ACADS ACAD3, SCAD ENSG00000122971 Acyl-CoA dehydrogenase, C-2 to C-3 short chain 12 120725735-120740008 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004799, CAB019284, HPA022271 Enhanced Enhanced Mitochondria Renal cancer:3.33e-6 (favourable), Urothelial cancer:6.34e-5 (favourable), Liver cancer:2.43e-4 (favourable), Endometrial cancer:5.05e-4 (favourable), Glioma:9.94e-4 (unfavourable) Expressed in all Expressed in all duodenum: 81.2 Cell line enhanced HMC-1: 30.0 +HVCN1 Hv1, MGC15619, VSOP ENSG00000122986 Hydrogen voltage gated channel 1 12 110627841-110704950 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039329 Enhanced Expressed in all Mixed testis: 82.5 Cell line enhanced HL-60: 35.4;NB-4: 182.9;U-698: 61.5 +DDX54 APR-5, DP97, MGC2835 ENSG00000123064 DEAD-box helicase 54 12 113157174-113185479 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028244, HPA070786 Approved Approved Nucleus
Nucleoli
Golgi apparatus Liver cancer:1.39e-4 (unfavourable) Expressed in all Expressed in all appendix: 38.8 Expressed in all +MED13L KIAA1025, THRAP2, TRAP240L ENSG00000123066 Mediator complex subunit 13 like 12 115953872-116277338 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039445 Uncertain Approved Nucleus
Golgi apparatus Expressed in all Expressed in all bone marrow: 35.9 Expressed in all +CDKN2C INK4C, p18 ENSG00000123080 Cyclin dependent kinase inhibitor 2C 1 50960745-50974633 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005303, CAB018398, HPA019057, HPA019764 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.70e-10 (unfavourable), Liver cancer:1.58e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 80.3 Mixed +RNF11 CGI-123, MGC51169, Sid1669p ENSG00000123091 Ring finger protein 11 1 51236271-51273455 Predicted intracellular proteins Evidence at protein level HPA045781 Uncertain Renal cancer:3.14e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 151.4 Mixed +RASSF8 C12orf2, HoJ-1 ENSG00000123094 Ras association domain family member 8 12 25959029-26079892 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038163, HPA038164 Uncertain Approved Mitochondria
Cytosol Expressed in all Tissue enhanced testis: 106.4 endometrium: 47.0 Cell line enhanced U-2197: 100.3 +BHLHE41 BHLHB3, bHLHe41, DEC2, SHARP-1, SHARP1 ENSG00000123095 Basic helix-loop-helix family member e41 12 26120026-26125127 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056035 Approved Nucleoplasm Renal cancer:8.73e-5 (unfavourable), Urothelial cancer:1.09e-4 (favourable) Expressed in all Tissue enhanced thyroid gland: 94.5 fallopian tube: 70.9 Cell line enhanced RT4: 97.9;U-266/70: 39.0;U-87 MG: 42.7 +SSPN KRAG, SPN1, SPN2 ENSG00000123096 Sarcospan 12 26121991-26299290 Predicted membrane proteins Evidence at protein level HPA066432 Approved Nucleus
Nuclear membrane Renal cancer:2.77e-5 (unfavourable) Mixed Mixed cervix, uterine: 64.4 Cell line enhanced ASC diff: 18.2 +ITPR2 CFAP48, IP3R2 ENSG00000123104 Inositol 1,4,5-trisphosphate receptor type 2 12 26336515-26833198 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059144, HPA062260 Uncertain Supported Nucleus
Endoplasmic reticulum Expressed in all Mixed parathyroid gland: 26.2 Cell line enhanced TIME: 55.9 +CCDC91 DKFZp779L1558, FLJ11088, p56 ENSG00000123106 Coiled-coil domain containing 91 12 28133249-28581511 Predicted intracellular proteins Evidence at protein level HPA038169 Approved Supported Nucleoplasm
Golgi apparatus Liver cancer:1.05e-4 (unfavourable), Renal cancer:7.69e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 41.5 Mixed +NECAB1 EFCBP1 ENSG00000123119 N-terminal EF-hand calcium binding protein 1 8 90791550-90959408 Predicted intracellular proteins Evidence at protein level HPA023252, HPA023629, HPA025963, HPA031262, CAB068208, CAB068209, CAB068210 Enhanced Supported Supported Nucleoplasm
Cytosol Mixed Tissue enriched 10 cerebral cortex: 79.7 lung: 8.1 Mixed +WWP1 AIP5, DKFZP434D2111 ENSG00000123124 WW domain containing E3 ubiquitin protein ligase 1 8 86342738-86478420 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023180 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Renal cancer:5.45e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 183.6 Expressed in all +ACOT9 ACATE2, CGI-16, MT-ACT48 ENSG00000123130 Acyl-CoA thioesterase 9 X 23702253-23766475 Predicted intracellular proteins Evidence at protein level HPA035533 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:3.23e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 46.9 Mixed +PRDX4 AOE37-2 ENSG00000123131 Peroxiredoxin 4 X 23664262-23686399 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB008659, CAB027389, CAB047362 Enhanced Supported Endoplasmic reticulum
Cytosol Renal cancer:1.33e-6 (unfavourable) Expressed in all Expressed in all pancreas: 239.5 Expressed in all +DDX39A BAT1L, DDX39, DDXL, URH49 ENSG00000123136 DExD-box helicase 39A 19 14408819-14419383 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055334 Approved Approved Nuclear speckles Renal cancer:1.50e-10 (unfavourable), Cervical cancer:6.86e-4 (favourable) Expressed in all Expressed in all testis: 209.7 Expressed in all +PKN1 DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1 ENSG00000123143 Protein kinase N1 19 14433053-14471867 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003982, CAB010278 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all Expressed in all spleen: 85.9 Expressed in all +C19orf43 fSAP18, MGC2803 ENSG00000123144 Chromosome 19 open reading frame 43 19 12730640-12734775 Predicted intracellular proteins Evidence at protein level HPA059965 Approved Approved Nucleoplasm Expressed in all Expressed in all spleen: 125.2 Expressed in all +ADGRE5 CD97, TM7LN1 ENSG00000123146 Adhesion G protein-coupled receptor E5 19 14380501-14408725 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA013707 Enhanced Approved Cytosol Renal cancer:1.87e-6 (unfavourable), Liver cancer:3.73e-5 (unfavourable) Expressed in all Expressed in all spleen: 140.3 Mixed +WDR83 MORG1 ENSG00000123154 WD repeat domain 83 19 12666800-12675832 Predicted intracellular proteins Evidence at protein level HPA042629, HPA042838 Uncertain Approved Nucleoplasm
Vesicles
Centrosome Urothelial cancer:3.12e-4 (favourable), Pancreatic cancer:5.44e-4 (favourable) Expressed in all Mixed testis: 9.4 Mixed +GIPC1 C19orf3, GIPC, GLUT1CBP, Hs.6454, NIP, RGS19IP1, SEMCAP, SYNECTIN, TIP-2 ENSG00000123159 GIPC PDZ domain containing family member 1 19 14477760-14496149 Predicted intracellular proteins Evidence at protein level HPA043958, HPA061786 Approved Approved Nucleus
Plasma membrane
Cell Junctions Expressed in all Expressed in all esophagus: 103.9 Expressed in all +ACTRT1 AIP1, ARIP1, Arp-T1, KIAA0705 ENSG00000123165 Actin related protein T1 X 128050962-128052398 Predicted intracellular proteins Evidence at protein level HPA003119 Supported Not detected Tissue enriched 36 testis: 3.6 all non-specific tissues: 0.0 Not detected +CCDC70 DKFZP434K1172, FLJ25853 ENSG00000123171 Coiled-coil domain containing 70 13 51861981-51866232 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 1157 testis: 115.6 all non-specific tissues: 0.0 Not detected +SPRYD7 C13orf1, CLLD6 ENSG00000123178 SPRY domain containing 7 13 49912706-49936490 Predicted intracellular proteins Evidence at protein level HPA043934 Approved Approved Vesicles Cervical cancer:8.48e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 18.7 Mixed +EBPL EBRP ENSG00000123179 Emopamil binding protein like 13 49660723-49691475 Predicted membrane proteins Evidence at protein level HPA049891 Approved Supported Endoplasmic reticulum Renal cancer:7.18e-8 (unfavourable), Ovarian cancer:1.38e-4 (unfavourable) Expressed in all Expressed in all liver: 61.5 Expressed in all +ATP7B WND ENSG00000123191 ATPase copper transporting beta 13 51930436-52012125 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA009137, HPA013187 Supported Supported Golgi apparatus Endometrial cancer:5.01e-4 (unfavourable) Mixed Mixed testis: 13.9 Cell line enhanced BEWO: 31.8;HEL: 46.9;RPTEC TERT1: 22.2 +ZC3H13 DKFZp434D1812, KIAA0853 ENSG00000123200 Zinc finger CCCH-type containing 13 13 45954465-46052759 Predicted intracellular proteins Evidence at protein level HPA039340, HPA040140, HPA047806 Uncertain Approved Nuclear membrane
Actin filaments Renal cancer:2.69e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 33.5 Expressed in all +NLN AGTBP, KIAA1226 ENSG00000123213 Neurolysin 5 65722196-65871725 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031862 Approved Approved Mitochondria Renal cancer:5.58e-7 (favourable), Pancreatic cancer:7.51e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 8.2 Expressed in all +CENPK CENP-K, FKSG14, SOLT ENSG00000123219 Centromere protein K 5 65517766-65563171 Disease related genes, Predicted intracellular proteins Evidence at protein level Mixed Mixed testis: 24.7 Expressed in all +OPTN FIP-2, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP ENSG00000123240 Optineurin 10 13099449-13138308 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003279, HPA003360, CAB019303 Supported Enhanced Cytosol Renal cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 300.1 Mixed +ITIH5 MGC10848 ENSG00000123243 Inter-alpha-trypsin inhibitor heavy chain family member 5 10 7559270-7666998 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038305 Approved Approved Golgi apparatus
Vesicles Expressed in all Mixed placenta: 123.4 Cell line enriched 7 WM-115: 101.4 +ATF1 TREB36 ENSG00000123268 Activating transcription factor 1 12 50763710-50821122 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB016222, HPA055069, HPA055406 Enhanced Enhanced Nucleoplasm Liver cancer:1.53e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 39.6 Expressed in all +TSFM EF-TS, EF-Tsmt ENSG00000123297 Ts translation elongation factor, mitochondrial 12 57782589-57808071 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA006204 Supported Nucleus
Mitochondria Renal cancer:8.82e-4 (favourable) Expressed in all Expressed in all adrenal gland: 63.7 Cell line enriched 7 RH-30: 980.3 +NEUROD4 ATH-3, Atoh3, bHLHa4, MATH-3 ENSG00000123307 Neuronal differentiation 4 12 55019945-55030014 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015545 Supported Not detected Tissue enhanced adrenal gland: 2.3 testis: 0.5 Group enriched 8 AF22: 1.3;SCLC-21H: 3.3 +ARHGAP9 10C, MGC1295 ENSG00000123329 Rho GTPase activating protein 9 12 57472255-57488814 Predicted intracellular proteins Evidence at protein level Renal cancer:7.90e-9 (unfavourable), Endometrial cancer:6.61e-5 (favourable) Expressed in all Tissue enhanced bone marrow: 78.0 lymph node: 68.3 Cell line enhanced HEL: 24.8;HMC-1: 103.7;THP-1: 23.7 +NCKAP1L HEM1 ENSG00000123338 NCK associated protein 1 like 12 54497711-54548238 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA039490, HPA040772 Approved Uncertain Plasma membrane
Cytosol Expressed in all Mixed spleen: 54.9 Cell line enhanced HL-60: 89.0;HMC-1: 98.8;THP-1: 81.4;U-937: 55.5 +MMP19 MMP18, RASI-1 ENSG00000123342 Matrix metallopeptidase 19 12 55835433-55842966 Disease related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level HPA070804 Approved Endoplasmic reticulum
Vesicles Renal cancer:8.56e-9 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 64.2;gallbladder: 97.3 placenta: 28.2 Cell line enriched 7 BEWO: 141.1 +PFDN5 MM-1, PFD5 ENSG00000123349 Prefoldin subunit 5 12 53295291-53299450 Predicted intracellular proteins Evidence at protein level HPA008587 Approved Renal cancer:1.54e-6 (unfavourable), Pancreatic cancer:5.45e-4 (favourable) Expressed in all Expressed in all epididymis: 1080.1 Expressed in all +SPATS2 FLJ13117, SCR59, SPATA10 ENSG00000123352 Spermatogenesis associated serine rich 2 12 49366584-49527424 Predicted intracellular proteins Evidence at protein level HPA038642, HPA038643, HPA066105 Uncertain Enhanced Cytosol Liver cancer:9.57e-8 (unfavourable), Ovarian cancer:1.44e-4 (favourable), Renal cancer:5.20e-4 (unfavourable) Expressed in all Expressed in all testis: 49.6 Expressed in all +ORMDL2 adoplin-2, HSPC160, MST095, MSTP095 ENSG00000123353 ORMDL sphingolipid biosynthesis regulator 2 12 55817919-55821879 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA065643 Supported Endoplasmic reticulum Endometrial cancer:3.30e-5 (favourable), Liver cancer:9.75e-4 (unfavourable) Expressed in all Expressed in all epididymis: 62.6 Expressed in all +NR4A1 GFRP1, HMR, N10, NAK-1, NGFIB, NUR77, TR3 ENSG00000123358 Nuclear receptor subfamily 4 group A member 1 12 52022832-52059507 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059742, HPA070142 Approved Supported Nucleus
Cytosol Renal cancer:6.99e-4 (favourable) Expressed in all Expressed in all adrenal gland: 748.8 Cell line enhanced MCF7: 67.2;SK-BR-3: 60.1;SK-MEL-30: 111.2 +PDE1B PDES1B ENSG00000123360 Phosphodiesterase 1B 12 54549350-54579239 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018492 Approved Renal cancer:4.77e-6 (unfavourable) Mixed Tissue enhanced cerebral cortex: 18.4 parathyroid gland: 11.9 Cell line enhanced HDLM-2: 10.6;HL-60: 5.1;HMC-1: 10.2;NB-4: 5.1;THP-1: 5.1;U-937: 5.0 +HOXC13 HOX3, HOX3G ENSG00000123364 Homeobox C13 12 53938765-53946544 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051634 Supported Mixed Tissue enriched 8 skin: 4.6 breast,testis: 0.5 Cell line enhanced AN3-CA: 28.1;HaCaT: 56.8;SK-BR-3: 26.3;T-47d: 25.6 +CDK2 ENSG00000123374 Cyclin dependent kinase 2 12 55966769-55972784 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013115, HPA066915 Enhanced Enhanced Nucleoplasm
Centrosome
Cytosol Renal cancer:1.46e-10 (unfavourable), Liver cancer:8.61e-5 (unfavourable), Head and neck cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 65.5 Expressed in all +LRP1 A2MR, APOER, APR, CD91, LRP, LRP1A ENSG00000123384 LDL receptor related protein 1 12 57128493-57213351 Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004182, CAB018621, HPA022903 Supported Supported Nucleoplasm
Vesicles Urothelial cancer:1.29e-5 (unfavourable), Renal cancer:1.52e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 123.8 Cell line enhanced ASC diff: 333.3;ASC TERT1: 342.9;HSkMC: 232.4 +HOXC11 HOX3H ENSG00000123388 Homeobox C11 12 53973126-53977643 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA038291 Uncertain Supported Nucleoplasm
Cytosol Mixed Tissue enhanced skin: 2.2 testis: 1.1 Cell line enhanced AN3-CA: 32.1;BJ hTERT+: 14.2;T-47d: 25.7 +ATG101 C12orf44, FLJ11773 ENSG00000123395 Autophagy related 101 12 52069246-52077494 Predicted intracellular proteins Evidence at protein level HPA039904 Approved Liver cancer:8.07e-7 (unfavourable) Expressed in all Expressed in all gallbladder: 43.7 Expressed in all +NFE2 NF-E2 ENSG00000123405 Nuclear factor, erythroid 2 12 54292111-54301121 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001914 Enhanced Approved Nucleoplasm
Actin filaments Mixed Tissue enriched 6 bone marrow: 68.6 spleen: 11.9 Cell line enhanced HEL: 328.8;K-562: 144.5;NB-4: 71.3 +HOXC12 HOC3F, HOX3, HOX3F ENSG00000123407 Homeobox C12 12 53954834-53958956 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055632 Uncertain Mixed Not detected skin: 0.7 Group enriched 6 HaCaT: 20.3;K-562: 5.9;SiHa: 5.3 +IKZF4 Eos, ZNFN1A4 ENSG00000123411 IKAROS family zinc finger 4 12 56007659-56038435 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046270, HPA049016 Approved Supported Nucleoplasm
Nuclear bodies Lung cancer:3.46e-4 (favourable), Pancreatic cancer:4.37e-4 (favourable) Mixed Mixed parathyroid gland: 17.0 Cell line enhanced HDLM-2: 33.6 +SMUG1 FDG, HMUDG, UNG3 ENSG00000123415 Single-strand-selective monofunctional uracil-DNA glycosylase 1 12 54121277-54189008 Predicted intracellular proteins Evidence at protein level HPA051149, HPA071486 Approved Vesicles
Centrosome Ovarian cancer:1.31e-4 (favourable), Liver cancer:6.96e-4 (unfavourable) Expressed in all Expressed in all epididymis: 48.8 Expressed in all +TUBA1B K-ALPHA-1 ENSG00000123416 Tubulin alpha 1b 12 49127782-49131397 Predicted intracellular proteins Evidence at protein level CAB011513, HPA039247, HPA043684, HPA063394 Enhanced Supported Microtubules Renal cancer:2.85e-12 (unfavourable), Liver cancer:1.68e-7 (unfavourable), Breast cancer:5.49e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 1433.9 Expressed in all +METTL21B DKFZP586D0919, FAM119B ENSG00000123427 Methyltransferase like 21B 12 57771492-57782541 Predicted intracellular proteins Evidence at protein level HPA043020 Uncertain Approved Nucleoplasm Expressed in all Expressed in all thyroid gland: 16.8 Cell line enriched 9 RH-30: 142.0 +KBTBD4 BKLHD4, FLJ10450, HSPC252 ENSG00000123444 Kelch repeat and BTB domain containing 4 11 47572197-47579015 Predicted intracellular proteins Evidence at protein level HPA037792, HPA037793 Uncertain Approved Nucleus
Vesicles
Cytosol Renal cancer:2.70e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 48.6 Expressed in all +SARDH DMGDHL1, SDH ENSG00000123453 Sarcosine dehydrogenase 9 133663560-133739955 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA057267, HPA058086 Approved Approved Mitochondria Glioma:3.50e-4 (unfavourable) Tissue enriched Tissue enhanced epididymis: 59.3;liver: 43.0 kidney: 12.5 Group enriched 5 AN3-CA: 16.3;Hep G2: 20.7;LHCN-M2: 9.2;MOLT-4: 18.0;RH-30: 17.5;RPMI-8226: 26.5;SH-SY5Y: 15.4 +DBH DBM ENSG00000123454 Dopamine beta-hydroxylase 9 133636360-133659344 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002130, HPA005960, HPA070789 Enhanced Enhanced Endoplasmic reticulum
Vesicles Mixed Tissue enriched 28 adrenal gland: 356.8 liver: 12.6 Cell line enriched 370 SH-SY5Y: 1924.2 +ATPAF1 ATP11, Atp11p, FLJ22351 ENSG00000123472 ATP synthase mitochondrial F1 complex assembly factor 1 1 46632737-46673867 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028382, HPA044950 Approved Approved Mitochondria Renal cancer:5.33e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 176.2 Expressed in all +STIL MCPH7, SIL ENSG00000123473 SCL/TAL1 interrupting locus 1 47250139-47314147 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046543 Approved Plasma membrane
Cytosol Pancreatic cancer:1.33e-4 (unfavourable) Mixed Mixed testis: 12.9 Mixed +HJURP DKFZp762E1312, FAKTS, hFLEG1, URLC9 ENSG00000123485 Holliday junction recognition protein 2 233833416-233854566 Predicted intracellular proteins Evidence at protein level HPA008436, HPA027261 Uncertain Enhanced Nucleus
Nucleoli
Cytosol Liver cancer:3.37e-5 (unfavourable), Pancreatic cancer:7.72e-5 (unfavourable), Lung cancer:2.46e-4 (unfavourable), Melanoma:6.49e-4 (unfavourable) Mixed Tissue enhanced bone marrow: 28.7;testis: 20.0 lymph node: 15.1 Mixed +IL13RA2 CD213a2, CT19, IL-13R, IL13BP ENSG00000123496 Interleukin 13 receptor subunit alpha 2 X 115003975-115019977 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level Liver cancer:3.55e-4 (favourable) Tissue enhanced Tissue enriched 8 testis: 52.8 prostate: 6.8 Group enriched 9 PC-3: 120.8;U-2197: 386.1;U-251 MG: 238.2;U-87 MG: 159.9 +COL10A1 ENSG00000123500 Collagen type X alpha 1 chain 6 116118923-116158747 Disease related genes, Predicted secreted proteins Evidence at protein level HPA053268 Approved Endoplasmic reticulum Tissue enhanced Tissue enhanced gallbladder: 14.5 ovary: 4.9 Cell line enriched 6 hTEC/SVTERT24-B: 39.7 +AMD1 SAMDC ENSG00000123505 Adenosylmethionine decarboxylase 1 6 110874770-110895713 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029281, HPA029282 Approved Approved Nucleoplasm Liver cancer:1.91e-6 (unfavourable), Breast cancer:3.87e-4 (unfavourable), Renal cancer:4.28e-4 (favourable) Expressed in all Expressed in all prostate: 323.8 Expressed in all +NDUFAF4 bA22L21.1, C6orf66, HRPAP20, HSPC125, My013 ENSG00000123545 NADH:ubiquinone oxidoreductase complex assembly factor 4 6 96889313-96897881 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046560 Uncertain Supported Mitochondria Breast cancer:1.31e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 29.0 Expressed in all +USP45 MGC14793 ENSG00000123552 Ubiquitin specific peptidase 45 6 99432379-99521728 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029602, HPA029604 Uncertain Approved Nucleus
Cytosol Expressed in all Mixed gallbladder: 9.9 Expressed in all +PLP1 GPM6C, PLP, SPG2 ENSG00000123560 Proteolipid protein 1 X 103773718-103792619 Cancer-related genes, Disease related genes, Predicted membrane proteins Evidence at protein level HPA004128 Enhanced Group enriched Tissue enriched 30 cerebral cortex: 3216.6 parathyroid gland: 107.9 Group enriched 6 NTERA-2: 37.4;SK-MEL-30: 184.2;WM-115: 137.4 +SERPINA7 TBG ENSG00000123561 Serpin family A member 7 X 106032442-106038738 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002803 Approved Tissue enriched Tissue enriched 288 liver: 216.0 small intestine: 0.7 Cell line enriched 406 Hep G2: 71.5 +MORF4L2 KIAA0026, MRGX ENSG00000123562 Mortality factor 4 like 2 X 103675496-103688158 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031872, HPA054102 Supported Enhanced Nucleus Renal cancer:7.86e-7 (unfavourable), Head and neck cancer:4.29e-5 (unfavourable), Breast cancer:9.83e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 493.3 Expressed in all +H2BFWT ENSG00000123569 H2B histone family member W, testis specific X 104011147-104013687 Predicted intracellular proteins Evidence at protein level HPA056289 Uncertain Not detected Not detected testis: 0.6 Not detected +RAB9B RAB9L ENSG00000123570 RAB9B, member RAS oncogene family X 103822322-103832228 Predicted secreted proteins Evidence at protein level HPA061932 Enhanced Mixed Mixed heart muscle: 14.6 Mixed +NRK DKFZp686A17109 ENSG00000123572 Nik related kinase X 105822543-105958610 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017238 Uncertain Approved Nucleoplasm
Cytosol Tissue enriched Tissue enhanced ovary: 39.8;placenta: 34.3 adrenal gland: 21.0 Cell line enhanced fHDF/TERT166: 45.0;RH-30: 12.4;RPTEC TERT1: 26.3 +FAM199X CXorf39 ENSG00000123575 Family with sequence similarity 199, X-linked X 104166620-104195902 Predicted intracellular proteins Evidence at protein level HPA003093 Approved Approved Nucleus
Golgi apparatus
Cytosol Expressed in all Expressed in all epididymis: 43.4 Expressed in all +ESX1 ESX1L, ESXR1 ENSG00000123576 ESX homeobox 1 X 104250038-104254933 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051992 Enhanced Supported Nuclear speckles Tissue enriched Tissue enriched 63 testis: 12.0 placenta: 0.1 Cell line enriched 9 TIME: 20.3 +MAGEA9 CT1.9, MAGE9, MGC8421 ENSG00000123584 MAGE family member A9 X 149781930-149787737 Predicted intracellular proteins Evidence at protein level Not detected Not detected testis: 0.6 Group enriched 7 U-266/70: 34.5;U-266/84: 23.0 +ATXN3L MJDL ENSG00000123594 Ataxin 3 like X 13318236-13320399 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024123, HPA027539 Uncertain Not detected Tissue enriched 37 testis: 4.9 placenta: 0.1 Not detected +RAB9A RAB9 ENSG00000123595 RAB9A, member RAS oncogene family X 13689125-13710506 Predicted intracellular proteins Evidence at protein level HPA003094, CAB016411 Enhanced Uncertain Nucleoplasm
Cytosol Renal cancer:3.35e-5 (favourable) Expressed in all Expressed in all adrenal gland: 68.1 Expressed in all +METTL8 FLJ13984, TIP ENSG00000123600 Methyltransferase like 8 2 171317405-171434802 Predicted intracellular proteins Evidence at protein level HPA035421 Uncertain Approved Cytosol Endometrial cancer:2.00e-4 (unfavourable), Renal cancer:6.75e-4 (unfavourable) Expressed in all Mixed smooth muscle: 14.7 Expressed in all +TTC21B FLJ11457, IFT139B, JBTS11, NPHP12, THM1 ENSG00000123607 Tetratricopeptide repeat domain 21B 2 165857475-165953843 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035494, HPA035495 Uncertain Supported Mitochondria Renal cancer:1.36e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 14.4 Mixed +NMI ENSG00000123609 N-myc and STAT interactor 2 151270465-151290057 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008588 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.57e-7 (unfavourable), Liver cancer:1.15e-4 (unfavourable), Pancreatic cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all spleen: 46.9 Mixed +TNFAIP6 TSG-6, TSG6 ENSG00000123610 TNF alpha induced protein 6 2 151357592-151380048 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB032719, HPA050884 Approved Cervical cancer:8.18e-5 (unfavourable), Urothelial cancer:9.16e-5 (unfavourable), Renal cancer:5.59e-4 (unfavourable) Tissue enhanced Tissue enhanced appendix: 38.7;gallbladder: 31.8 adipose tissue: 18.7 Cell line enhanced BJ hTERT+: 54.6;HHSteC: 33.8;hTEC/SVTERT24-B: 54.8;U-2197: 41.1 +ACVR1C ACVRLK7, ALK7 ENSG00000123612 Activin A receptor type 1C 2 157526767-157629005 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007982, HPA011933 Approved Mixed Tissue enriched 8 adipose tissue: 34.1 ovary: 4.3 Cell line enhanced ASC diff: 7.5;HDLM-2: 4.8 +BAZ2B WALp4 ENSG00000123636 Bromodomain adjacent to zinc finger domain 2B 2 159318979-159616692 Predicted intracellular proteins Evidence at protein level HPA019819, HPA059292 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 55.5 Mixed +SLC36A1 LYAAT-1, PAT1, TRAMD3 ENSG00000123643 Solute carrier family 36 member 1 5 151437046-151492381 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA035937 Approved Renal cancer:1.83e-6 (unfavourable), Liver cancer:6.30e-5 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 65.4 duodenum: 44.3 Mixed +LPGAT1 FAM34A, FAM34A1, KIAA0205, NET8 ENSG00000123684 Lysophosphatidylglycerol acyltransferase 1 1 211743457-211830772 Predicted membrane proteins Evidence at protein level HPA008304 Approved Expressed in all Expressed in all thyroid gland: 43.1 Mixed +BATF3 JDP1, JUNDM1, SNFT ENSG00000123685 Basic leucine zipper ATF-like transcription factor 3 1 212686418-212699985 Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Mixed spleen: 4.6 Cell line enriched 25 HDLM-2: 359.9 +G0S2 ENSG00000123689 G0/G1 switch 2 1 209675420-209676388 Predicted intracellular proteins Evidence at protein level Glioma:2.22e-4 (unfavourable), Renal cancer:3.14e-4 (unfavourable), Colorectal cancer:7.72e-4 (unfavourable) Expressed in all Group enriched 5 adipose tissue: 956.0;bone marrow: 937.9;skeletal muscle: 240.5 appendix: 138.1 Cell line enhanced ASC diff: 321.2;HBEC3-KT: 528.5;PC-3: 170.1;RPMI-8226: 166.8 +KCNJ2 IRK1, Kir2.1, LQT7 ENSG00000123700 Potassium voltage-gated channel subfamily J member 2 17 70168673-70180048 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA029109 Approved Mixed Tissue enhanced parathyroid gland: 44.6 fallopian tube: 10.6 Cell line enhanced REH: 6.8;RH-30: 28.3;U-138 MG: 10.5 +RAP2C DKFZp313B211 ENSG00000123728 RAP2C, member of RAS oncogene family X 132203024-132219480 Predicted intracellular proteins Evidence at protein level Renal cancer:3.81e-5 (unfavourable) Expressed in all Expressed in all endometrium: 102.6 Expressed in all +EXOSC9 p5, p6, PM/Scl-75, PMSCL1, RRP45, Rrp45p ENSG00000123737 Exosome component 9 4 121801317-121817021 Predicted intracellular proteins Evidence at protein level HPA041838, HPA048257, CAB070171 Approved Enhanced Nucleus
Nucleoli Liver cancer:1.04e-4 (unfavourable), Renal cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all testis: 90.4 Expressed in all +PLA2G12A PLA2G12 ENSG00000123739 Phospholipase A2 group XIIA 4 109709989-109730077 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA035908, HPA035909 Approved Renal cancer:2.54e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 34.0 Expressed in all +B9D2 MGC4093, MKS10 ENSG00000123810 B9 protein domain 2 19 41354421-41364173 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042229, HPA042618 Enhanced Melanoma:6.39e-4 (unfavourable) Expressed in all Mixed fallopian tube: 16.8 Expressed in all +COQ8B ADCK4, COQ8, FLJ12229 ENSG00000123815 Coenzyme Q8B 19 40691529-40718207 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027229, HPA027277, HPA027279, HPA028303 Enhanced Enhanced Mitochondria Expressed in all Expressed in all fallopian tube: 41.1 Expressed in all +PFKFB2 ENSG00000123836 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 207034366-207081024 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049975, HPA063575 Uncertain Enhanced Nucleus Renal cancer:3.23e-7 (favourable), Thyroid cancer:8.63e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 86.2 Mixed +C4BPA C4BP ENSG00000123838 Complement component 4 binding protein alpha 1 207104262-207144972 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA000926, HPA001578 Enhanced Endometrial cancer:6.37e-5 (favourable), Liver cancer:2.24e-4 (favourable) Tissue enriched Group enriched 65 liver: 997.5;lung: 262.3 cervix, uterine: 9.6 Cell line enriched 6 Hep G2: 25.8 +C4BPB C4BP ENSG00000123843 Complement component 4 binding protein beta 1 207088842-207099993 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA051620 Approved Tissue enriched Group enriched 16 liver: 241.3;ovary: 52.0 placenta: 8.9 Group enriched 15 CACO-2: 94.2;HeLa: 31.3;Hep G2: 101.7 +RAB38 NY-MEL-1 ENSG00000123892 RAB38, member RAS oncogene family 11 88113242-88175467 Predicted intracellular proteins Evidence at protein level HPA071701 Uncertain Nuclear bodies
Mitochondria Renal cancer:8.26e-4 (favourable) Expressed in all Tissue enhanced skin: 47.4 esophagus: 36.3 Cell line enhanced hTCEpi: 216.3;hTERT-HME1: 203.2;SK-MEL-30: 129.2 +GPR83 GPR72 ENSG00000123901 G protein-coupled receptor 83 11 94377311-94401419 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Mixed Group enriched 6 adrenal gland: 1.0;cerebral cortex: 4.6;thyroid gland: 5.1 skin,testis: 0.5 Cell line enhanced CACO-2: 1.4 +AGO2 CASC7, EIF2C2, hAGO2, LINC00980, Q10 ENSG00000123908 Argonaute 2, RISC catalytic component 8 140520156-140635619 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB019309, HPA058075 Approved Supported Nucleoplasm
Cell Junctions Renal cancer:1.82e-5 (unfavourable), Endometrial cancer:1.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 12.0 Expressed in all +MXD4 bHLHc12, MAD4, MST149, MSTP149 ENSG00000123933 MAX dimerization protein 4 4 2247432-2262294 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053363 Supported Cytosol Pancreatic cancer:1.39e-5 (favourable), Head and neck cancer:2.21e-5 (favourable) Expressed in all Expressed in all spleen: 41.3 Expressed in all +CKS2 ENSG00000123975 CDC28 protein kinase regulatory subunit 2 9 89311198-89316703 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA003424, HPA030762 Approved Supported Approved Nucleus
Vesicles
Mitochondria
Cytosol Liver cancer:2.51e-6 (unfavourable), Renal cancer:1.78e-5 (unfavourable), Pancreatic cancer:6.85e-4 (unfavourable) Expressed in all Tissue enhanced testis: 341.7 lymph node: 122.6 Expressed in all +DAW1 FLJ25955, ODA16, WDR69 ENSG00000123977 Dynein assembly factor with WD repeats 1 2 227871054-227924344 Predicted intracellular proteins Evidence at protein level HPA046118 Approved Approved Nucleoplasm
Nuclear bodies Mixed Group enriched 14 fallopian tube: 51.4;testis: 92.1 lung: 4.9 Cell line enhanced HUVEC TERT2: 18.4;U-2197: 40.4 +ACSL3 ACS3, FACL3, PRO2194 ENSG00000123983 Acyl-CoA synthetase long-chain family member 3 2 222860934-222944639 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011315, HPA071021 Uncertain Approved Nucleoli
Lipid droplets Liver cancer:2.75e-4 (unfavourable), Lung cancer:8.78e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 682.1 Expressed in all +CHPF CHSY2, CSS2 ENSG00000123989 Chondroitin polymerizing factor 2 219538947-219543787 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035123 Approved Supported Vesicles
Centrosome
Cytosol Cervical cancer:1.57e-4 (unfavourable), Head and neck cancer:1.68e-4 (unfavourable), Urothelial cancer:2.96e-4 (unfavourable), Glioma:9.56e-4 (unfavourable) Expressed in all Expressed in all testis: 77.2 Mixed +DNPEP ASPEP, DAP ENSG00000123992 Aspartyl aminopeptidase 2 219373546-219400022 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036398, HPA044860 Enhanced Supported Cytosol Expressed in all Expressed in all testis: 65.4 Expressed in all +INHA ENSG00000123999 Inhibin alpha subunit 2 219569162-219575713 Predicted secreted proteins Evidence at protein level CAB000047, HPA019141 Enhanced Approved Vesicles Renal cancer:4.03e-5 (unfavourable) Mixed Tissue enhanced adrenal gland: 51.5;ovary: 38.0;testis: 106.3 placenta: 14.9 Cell line enhanced HEL: 3.7;SK-BR-3: 6.8 +MOGAT1 DGAT2L, DGAT2L1, MGAT1 ENSG00000124003 Monoacylglycerol O-acyltransferase 1 2 222671786-222709930 Enzymes, Predicted membrane proteins Evidence at transcript level HPA049944 Uncertain Tissue enhanced Tissue enriched 10 gallbladder: 30.7 parathyroid gland: 2.9 Not detected +OBSL1 KIAA0657 ENSG00000124006 Obscurin like 1 2 219550729-219571859 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036404, HPA036405 Approved Approved Centrosome Glioma:8.52e-4 (unfavourable) Expressed in all Expressed in all ovary: 220.5 Cell line enhanced BEWO: 148.8 +FAM124B FLJ22746 ENSG00000124019 Family with sequence similarity 124 member B 2 224378698-224402085 Predicted intracellular proteins Evidence at protein level HPA070240 Approved Approved Nucleoplasm
Mitochondria Tissue enriched Tissue enhanced parathyroid gland: 9.8;placenta: 12.5 lung,smooth muscle: 3.6 Cell line enriched 7 HUVEC TERT2: 88.9 +SLC12A4 KCC1 ENSG00000124067 Solute carrier family 12 member 4 16 67943474-67969601 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA041138 Approved Approved Endosomes Renal cancer:2.25e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 63.9 Mixed +ENKD1 C16orf48, DKFZP434A1319 ENSG00000124074 Enkurin domain containing 1 16 67662945-67667265 Predicted intracellular proteins Evidence at protein level HPA041163, HPA041478 Approved Supported Plasma membrane
Centrosome
Cytosol Endometrial cancer:1.68e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 32.7 Mixed +MC3R MC3 ENSG00000124089 Melanocortin 3 receptor 20 56248732-56249815 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected testis: 0.1 Not detected +GCNT7 C20orf105, dJ1153D9.2 ENSG00000124091 Glucosaminyl (N-acetyl) transferase family member 7 20 56491492-56525925 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA052617 Uncertain Not detected Tissue enriched 5 bone marrow: 2.8 skin,testis: 0.5 Not detected +CTCFL BORIS, CT27, dJ579F20.2 ENSG00000124092 CCCTC-binding factor like 20 57495966-57525652 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA001472 Enhanced Tissue enhanced Tissue enriched 20 testis: 20.6 bone marrow: 1.0 Group enriched 41 HMC-1: 70.0;K-562: 103.5 +FAM210B C20orf108, dJ1167H4.1, DKFZP434A1114 ENSG00000124098 Family with sequence similarity 210 member B 20 56358915-56368663 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042652 Approved Approved Plasma membrane
Cytosol Renal cancer:1.44e-10 (favourable), Lung cancer:4.26e-4 (favourable), Cervical cancer:5.44e-4 (favourable) Expressed in all Expressed in all ovary: 131.4 Cell line enhanced SK-MEL-30: 224.0 +PI3 cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14 ENSG00000124102 Peptidase inhibitor 3 20 45174876-45176544 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB009449, HPA017737 Enhanced Approved Plasma membrane Renal cancer:1.94e-8 (unfavourable), Ovarian cancer:3.84e-6 (unfavourable), Pancreatic cancer:6.89e-4 (unfavourable), Breast cancer:6.94e-4 (favourable) Tissue enhanced Group enriched 15 esophagus: 2285.4;tonsil: 1739.8 appendix: 133.6 Group enriched 7 EFO-21: 78.9;HaCaT: 92.0;PC-3: 163.0 +FAM209A C20orf106, dJ1153D9.3 ENSG00000124103 Family with sequence similarity 209 member A 20 56517187-56526142 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 10 testis: 100.6 bone marrow: 9.6 Cell line enhanced HMC-1: 1.6;U-266/84: 1.0 +SNX21 C20orf161, dJ337O18.4, SNX-L ENSG00000124104 Sorting nexin family member 21 20 45833810-45843275 Predicted intracellular proteins Evidence at protein level HPA046359 Approved Approved Vesicles
Microtubule organizing center Expressed in all Mixed skin: 25.5 Cell line enhanced PC-3: 28.8;U-87 MG: 27.0 +SLPI ALK1, ALP, BLPI, HUSI, HUSI-I, WAP4, WFDC4 ENSG00000124107 Secretory leukocyte peptidase inhibitor 20 45252239-45254564 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB002303, HPA027774 Enhanced Renal cancer:6.91e-5 (unfavourable) Expressed in all Tissue enriched 9 cervix, uterine: 41087.8 seminal vesicle: 4333.6 Cell line enhanced EFO-21: 1622.9;hTCEpi: 1467.1;SiHa: 660.2 +WFDC3 dJ447F3.3, WAP14 ENSG00000124116 WAP four-disulfide core domain 3 20 45747944-45791932 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enriched 19 testis: 31.9 breast: 1.7 Cell line enhanced PC-3: 1.1 +TTPAL C20orf121, dJ179M20.3 ENSG00000124120 Alpha tocopherol transfer protein like 20 44475886-44494603 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046957, HPA066532 Uncertain Approved Golgi apparatus
Cytosol Endometrial cancer:3.47e-5 (unfavourable), Renal cancer:8.09e-5 (unfavourable), Head and neck cancer:2.94e-4 (unfavourable) Expressed in all Mixed skin: 14.9 Expressed in all +PREX1 KIAA1415, P-REX1 ENSG00000124126 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 20 48624252-48827883 Predicted intracellular proteins Evidence at protein level HPA001927 Supported Supported Vesicles
Cytosol Head and neck cancer:8.56e-4 (favourable) Expressed in all Expressed in all spleen: 60.8 Cell line enhanced MCF7: 124.7;SK-BR-3: 123.7;T-47d: 138.8 +KCNS1 Kv9.1 ENSG00000124134 Potassium voltage-gated channel modifier subfamily S member 1 20 45092310-45101112 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Ovarian cancer:6.45e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 9.3;gallbladder: 3.8;seminal vesicle: 4.2 testis: 1.7 Cell line enhanced HBF TERT88: 1.3;HHSteC: 1.8;THP-1: 1.2;U-87 MG: 3.0 +SLC12A5 KCC2, KIAA1176 ENSG00000124140 Solute carrier family 12 member 5 20 46021690-46060152 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA072058 Enhanced Glioma:8.45e-4 (unfavourable) Mixed Tissue enriched 8 cerebral cortex: 94.2 adrenal gland: 11.9 Cell line enhanced NB-4: 32.3;U-2 OS: 29.1 +ARHGAP40 C20orf95, dJ1100H13.4 ENSG00000124143 Rho GTPase activating protein 40 20 38601934-38651035 Predicted intracellular proteins Evidence at protein level HPA042636, HPA042840 Uncertain Supported Nucleoplasm
Plasma membrane
Centrosome
Cytosol Renal cancer:2.89e-4 (unfavourable) Mixed Group enriched 7 breast: 38.1;epididymis: 43.7;esophagus: 12.6;seminal vesicle: 11.3;skin: 53.8 prostate: 4.4 Cell line enhanced BEWO: 8.0;HBEC3-KT: 9.7;RPTEC TERT1: 8.8;SK-BR-3: 9.5;T-47d: 14.4 +SDC4 amphiglycan, ryudocan, SYND4 ENSG00000124145 Syndecan 4 20 45325288-45348424 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level HPA005716, CAB013240 Supported Approved Golgi apparatus
Plasma membrane Renal cancer:2.44e-7 (favourable), Thyroid cancer:2.67e-4 (favourable), Pancreatic cancer:4.20e-4 (unfavourable) Expressed in all Expressed in all lung: 250.2 Mixed +NCOA3 ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1 ENSG00000124151 Nuclear receptor coactivator 3 20 47501902-47656877 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009800, HPA024210 Supported Supported Nucleoplasm
Cytosol Liver cancer:8.09e-4 (unfavourable) Expressed in all Expressed in all lymph node: 44.8 Expressed in all +PIGT ENSG00000124155 Phosphatidylinositol glycan anchor biosynthesis class T 20 45416067-45456934 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Pancreatic cancer:2.51e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 123.1 Expressed in all +SEMG2 SGII ENSG00000124157 Semenogelin II 20 45221300-45224458 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA042767, HPA042835 Enhanced Tissue enriched Tissue enriched 18571 seminal vesicle: 14103.4 cervix, uterine,kidney: 0.7 Not detected +MATN4 ENSG00000124159 Matrilin 4 20 45293445-45308529 Plasma proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced breast: 3.0;pancreas: 5.9;skin: 3.5 cervix, uterine: 1.4 Cell line enhanced NB-4: 1.7;U-937: 1.0 +NCOA5 bA465L10.6, CIA ENSG00000124160 Nuclear receptor coactivator 5 20 46060985-46089952 Predicted intracellular proteins Evidence at protein level HPA050231 Uncertain Supported Nucleus
Actin filaments Liver cancer:1.41e-5 (unfavourable), Pancreatic cancer:1.09e-4 (favourable), Lung cancer:8.07e-4 (favourable) Expressed in all Expressed in all testis: 48.0 Expressed in all +VAPB ALS8, VAP-B, VAP-C ENSG00000124164 VAMP associated protein B and C 20 58389122-58451101 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA013144, CAB013722 Supported Enhanced Endoplasmic reticulum Renal cancer:1.08e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 42.4 Expressed in all +PARD6B PAR-6B ENSG00000124171 Par-6 family cell polarity regulator beta 20 50731544-50756795 Predicted intracellular proteins Evidence at protein level HPA013376 Uncertain Supported Cytosol Liver cancer:1.02e-5 (unfavourable), Renal cancer:6.38e-5 (favourable), Pancreatic cancer:8.38e-4 (unfavourable) Expressed in all Mixed kidney: 16.7 Cell line enhanced CACO-2: 23.7;MCF7: 39.2;T-47d: 45.5 +ATP5E ENSG00000124172 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 20 59025467-59032382 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:2.82e-4 (unfavourable) Expressed in all Expressed in all appendix: 132.8 Expressed in all +CHD6 CHD5, dJ620E11.1, FLJ22369, KIAA1335, RIGB ENSG00000124177 Chromodomain helicase DNA binding protein 6 20 41402101-41618494 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015543 Approved Nucleus Lung cancer:3.42e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 31.5 Expressed in all +PLCG1 NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1 ENSG00000124181 Phospholipase C gamma 1 20 41136960-41196801 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004277, HPA036681, HPA036682 Approved Supported Cytosol Pancreatic cancer:4.72e-4 (favourable) Expressed in all Expressed in all endometrium: 47.6 Expressed in all +TOX2 C20orf100, dJ1108D11.2, GCX-1 ENSG00000124191 TOX high mobility group box family member 2 20 43914864-44069616 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049900, HPA058396 Approved Supported Nucleoplasm Renal cancer:7.45e-8 (unfavourable), Endometrial cancer:2.60e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 19.8 Cell line enhanced HHSteC: 99.2;U-266/70: 59.6 +SRSF6 B52, SFRS6, SRP55 ENSG00000124193 Serine and arginine rich splicing factor 6 20 43457928-43464247 Predicted intracellular proteins Evidence at protein level HPA029005, CAB034889 Supported Supported Nuclear speckles Renal cancer:2.82e-4 (unfavourable), Liver cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all endometrium: 83.5 Expressed in all +GDAP1L1 ENSG00000124194 Ganglioside induced differentiation associated protein 1 like 1 20 44247099-44280917 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054182, HPA063265 Approved Approved Endoplasmic reticulum Tissue enriched Tissue enriched 20 cerebral cortex: 55.6 adrenal gland: 2.8 Group enriched 6 NTERA-2: 11.9;SCLC-21H: 34.5;SH-SY5Y: 15.2 +GTSF1L C20orf65, dJ1028D15.4, FAM112A ENSG00000124196 Gametocyte specific factor 1 like 20 43726164-43726998 Predicted intracellular proteins Evidence at protein level HPA054694 Enhanced Uncertain Nucleoli Tissue enriched Tissue enriched 160 testis: 269.9 lymph node: 1.6 Cell line enhanced REH: 1.0 +ARFGEF2 BIG2 ENSG00000124198 ADP ribosylation factor guanine nucleotide exchange factor 2 20 48921890-49036693 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026078, CAB026382 Supported Supported Golgi apparatus Renal cancer:6.15e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 174.4 Expressed in all +ZNFX1 FLJ11277, KIAA1404 ENSG00000124201 Zinc finger NFX1-type containing 1 20 49237946-49278426 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046629 Approved Approved Mitochondria Expressed in all Expressed in all parathyroid gland: 27.1 Expressed in all +ZNF831 C20orf174, dJ492J12.1 ENSG00000124203 Zinc finger protein 831 20 59123381-59259113 Predicted intracellular proteins Evidence at protein level HPA016839 Uncertain Not detected Tissue enhanced lymph node: 7.1 spleen: 3.6 Cell line enhanced Daudi: 2.9 +EDN3 ET3 ENSG00000124205 Endothelin 3 20 59300427-59325992 Disease related genes, Predicted secreted proteins Evidence at protein level HPA036618 Supported Glioma:2.38e-4 (favourable) Mixed Tissue enhanced small intestine: 39.3 duodenum: 38.3 Not detected +CSE1L CAS, CSE1, XPO2 ENSG00000124207 Chromosome segregation 1 like 20 49046246-49096960 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB002140, HPA038059, HPA038060 Enhanced Enhanced Nucleoplasm
Cytosol Liver cancer:2.42e-8 (unfavourable), Endometrial cancer:2.91e-5 (unfavourable), Renal cancer:1.89e-4 (unfavourable), Urothelial cancer:6.91e-4 (unfavourable) Expressed in all Expressed in all testis: 159.7 Expressed in all +TMEM189-UBE2V1 CROC-1B, Kua-UEV ENSG00000124208 TMEM189-UBE2V1 readthrough 20 50081124-50153637 Predicted membrane proteins Evidence at protein level HPA052535, HPA053186 Supported Nucleoplasm Not detected Mixed placenta: 5.6 Mixed +RAB22A ENSG00000124209 RAB22A, member RAS oncogene family 20 58309696-58367507 Predicted intracellular proteins Evidence at protein level HPA058894, HPA066920 Approved Uncertain Centrosome Liver cancer:7.33e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.1 Expressed in all +PTGIS CYP8A1, PGIS ENSG00000124212 Prostaglandin I2 synthase 20 49503874-49568146 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB009517, HPA014193, HPA052244 Enhanced Approved Endoplasmic reticulum Renal cancer:4.74e-8 (unfavourable), Urothelial cancer:9.99e-5 (unfavourable) Expressed in all Mixed fallopian tube: 78.2 Cell line enhanced ASC diff: 30.9;ASC TERT1: 31.6;U-2197: 133.1 +STAU1 PPP1R150, STAU ENSG00000124214 Staufen double-stranded RNA binding protein 1 20 49113339-49188367 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB020839, HPA049892 Approved Supported Cytosol Prostate cancer:4.41e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 140.5 Expressed in all +CDH26 VR20 ENSG00000124215 Cadherin 26 20 59958427-60034011 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA015722, HPA047578 Uncertain Approved Plasma membrane
Microtubules Lung cancer:3.75e-4 (favourable), Cervical cancer:7.62e-4 (favourable) Group enriched Tissue enhanced prostate: 19.1 urinary bladder: 6.1 Cell line enriched 6 RT4: 42.4 +SNAI1 SLUGH2, SNA, SNAH, SNAIL, SNAIL1 ENSG00000124216 Snail family transcriptional repressor 1 20 49982999-49988886 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005883, HPA056831, HPA069985, CAB078687 Supported Supported Nucleus
Cytosol Renal cancer:2.63e-7 (unfavourable), Thyroid cancer:8.82e-7 (unfavourable), Lung cancer:1.61e-5 (unfavourable), Colorectal cancer:4.76e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 26.2 thyroid gland: 13.4 Cell line enhanced SiHa: 30.1;TIME: 32.4;WM-115: 25.0 +MOCS3 dJ914P20.3, UBA4 ENSG00000124217 Molybdenum cofactor synthesis 3 20 50958826-50963931 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027556 Uncertain Liver cancer:1.39e-4 (unfavourable), Endometrial cancer:5.82e-4 (unfavourable), Renal cancer:7.55e-4 (favourable) Expressed in all Mixed testis: 5.2 Expressed in all +STX16 hsyn16, SYN16 ENSG00000124222 Syntaxin 16 20 58651253-58679526 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041019, HPA042033 Uncertain Enhanced Vesicles Renal cancer:1.11e-16 (unfavourable), Liver cancer:4.18e-4 (unfavourable) Expressed in all Expressed in all skin: 63.9 Expressed in all +PMEPA1 STAG1, TMEPAI ENSG00000124225 Prostate transmembrane protein, androgen induced 1 20 57648392-57711536 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA072291 Supported Vesicles Renal cancer:2.87e-7 (unfavourable), Lung cancer:4.73e-5 (unfavourable), Cervical cancer:2.45e-4 (unfavourable), Urothelial cancer:7.60e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 146.1;prostate: 179.6 endometrium: 60.3 Cell line enhanced SiHa: 218.5;U-251 MG: 397.1;WM-115: 233.9 +RNF114 PSORS12, ZNF313 ENSG00000124226 Ring finger protein 114 20 49936336-49953892 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021184 Approved Supported Plasma membrane
Cytosol Endometrial cancer:8.10e-6 (unfavourable), Thyroid cancer:3.01e-4 (favourable), Liver cancer:3.11e-4 (unfavourable) Expressed in all Expressed in all testis: 149.2 Expressed in all +ANKRD60 bA196N14.3, C20orf86 ENSG00000124227 Ankyrin repeat domain 60 20 58218495-58228653 Predicted secreted proteins Evidence at transcript level HPA060561 Uncertain Not detected Tissue enriched 47 testis: 4.7 all non-specific tissues: 0.0 Not detected +DDX27 dJ686N3.1, DRS1 ENSG00000124228 DEAD-box helicase 27 20 49219295-49244077 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047087 Uncertain Approved Nucleoli Liver cancer:6.70e-7 (unfavourable), Endometrial cancer:1.44e-5 (unfavourable), Renal cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all testis: 46.2 Expressed in all +RBPJL RBP-L, RBPSUHL, SUH, SUHL ENSG00000124232 Recombination signal binding protein for immunoglobulin kappa J region like 20 45306851-45317824 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB006846 Enhanced Group enriched Tissue enriched 151 pancreas: 205.8 stomach: 1.3 Not detected +SEMG1 CT103, SEMG ENSG00000124233 Semenogelin I 20 45206997-45209772 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA042476, HPA064892 Enhanced Tissue enriched Tissue enriched 17692 seminal vesicle: 41483.3 cervix, uterine: 2.3 Cell line enhanced NTERA-2: 1.2;THP-1: 2.0 +C20orf85 bA196N14.1, LLC1 ENSG00000124237 Chromosome 20 open reading frame 85 20 58150904-58161150 Predicted intracellular proteins Evidence at protein level HPA058271, HPA065540 Enhanced Tissue enhanced Tissue enriched 8 fallopian tube: 729.1 testis: 91.7 Not detected +BCAS4 CNOL, FLJ20495 ENSG00000124243 Breast carcinoma amplified sequence 4 20 50794894-50882676 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038812 Uncertain Approved Intermediate filaments
Cytosol Endometrial cancer:4.87e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 25.3 tonsil: 21.0 Cell line enhanced Daudi: 69.3;U-698: 59.0 +KCNK15 dJ781B1.1, K2p15.1, KCNK11, KCNK14, KIAA0237, KT3.3, TASK-5, TASK5 ENSG00000124249 Potassium two pore domain channel subfamily K member 15 20 44745780-44752313 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA064861 Uncertain Cervical cancer:3.68e-4 (unfavourable) Tissue enriched Tissue enhanced fallopian tube: 8.0 testis: 2.9 Cell line enriched 8 MCF7: 35.7 +TP53TG5 C20orf10, CLG01, dJ453C12.5 ENSG00000124251 TP53 target 5 20 45372563-45407889 Predicted intracellular proteins Evidence at protein level HPA041979 Enhanced Not detected Tissue enriched 12 testis: 22.2 cerebral cortex: 1.8 Cell line enhanced CACO-2: 1.6 +PCK1 PEPCK-C ENSG00000124253 Phosphoenolpyruvate carboxykinase 1 20 57561080-57568112 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006277, HPA006507, CAB017027 Approved Renal cancer:1.47e-5 (favourable) Tissue enriched Tissue enhanced kidney: 425.9;liver: 319.7 small intestine: 157.6 Cell line enriched 9 ASC diff: 14.0 +ZBP1 C20orf183, DAI, dJ718J7.3, DLM-1, DLM1 ENSG00000124256 Z-DNA binding protein 1 20 57603846-57620576 Predicted intracellular proteins Evidence at protein level HPA041256 Enhanced Mixed Mixed spleen: 29.8 Cell line enhanced Karpas-707: 24.3;U-266/70: 12.6;U-266/84: 16.2 +NEURL2 C20orf163, dJ337O18.6, FLJ30259, Ozz, Ozz-E3 ENSG00000124257 Neuralized E3 ubiquitin protein ligase 2 20 45888625-45891287 Predicted intracellular proteins Evidence at transcript level HPA043402, HPA059842 Approved Approved Vesicles Mixed Mixed ovary: 8.4 Mixed +MAGEA10 CT1.10, MAGE10, MGC10599 ENSG00000124260 MAGE family member A10 X 152133310-152138578 Predicted intracellular proteins Evidence at protein level HPA003333, HPA070780 Approved Supported Nucleoplasm
Cytosol Mixed Group enriched 13 placenta: 13.5;testis: 4.8 skin: 0.7 Group enriched 9 PC-3: 7.4;SH-SY5Y: 5.3;U-266/84: 4.0;WM-115: 12.8 +MTRR cblE ENSG00000124275 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 5 7851186-7906025 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038113 Supported Approved Nucleoplasm
Intermediate filaments
Cytosol Liver cancer:6.60e-4 (unfavourable) Expressed in all Expressed in all kidney: 20.5 Expressed in all +FASTKD3 FLJ23274, MGC5297 ENSG00000124279 FAST kinase domains 3 5 7859159-7869037 Predicted intracellular proteins Evidence at protein level HPA068525, HPA074462 Approved Supported Nucleus
Mitochondria Liver cancer:1.87e-5 (unfavourable), Urothelial cancer:8.53e-4 (favourable) Expressed in all Mixed parathyroid gland: 10.4 Expressed in all +PEPD ENSG00000124299 Peptidase D 19 33386950-33521794 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015599, HPA072045 Approved Supported Nucleoplasm Renal cancer:6.50e-9 (favourable) Expressed in all Expressed in all kidney: 342.6 Expressed in all +CHST8 GALNAC-4-ST1 ENSG00000124302 Carbohydrate sulfotransferase 8 19 33621955-33773509 Disease related genes, Predicted secreted proteins Evidence at protein level HPA016004 Supported Tissue enhanced Tissue enhanced cerebral cortex: 2.5 breast: 1.4 Group enriched 5 RPMI-8226: 16.8;SCLC-21H: 15.9;SH-SY5Y: 24.7 +IQSEC2 KIAA0522, MRX1, MRX18, MRX78 ENSG00000124313 IQ motif and Sec7 domain 2 X 53225828-53321328 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003973 Approved Vesicles Renal cancer:2.00e-4 (unfavourable), Urothelial cancer:2.38e-4 (favourable) Mixed Mixed cerebral cortex: 38.5 Cell line enhanced A549: 43.0 +VAMP7 SYBL1, TI-VAMP, VAMP-7 ENSG00000124333 Vesicle associated membrane protein 7 X 155881293-155943769 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036733 Approved Supported Vesicles Renal cancer:2.83e-4 (favourable) Expressed in all Expressed in all placenta: 57.2 Expressed in all +IL9R CD129 ENSG00000124334 Interleukin 9 receptor X 155997581-156010817 CD markers, Predicted membrane proteins Evidence at protein level HPA063240, HPA064557 Approved Urothelial cancer:1.90e-7 (favourable) Tissue enhanced Tissue enhanced urinary bladder: 8.4 lymph node: 2.8 Cell line enriched 10 HMC-1: 217.8 +XG PBDX ENSG00000124343 Xg blood group X 2752050-2815927 Blood group antigen proteins, Predicted membrane proteins Evidence at transcript level Breast cancer:4.25e-4 (unfavourable) Mixed Tissue enhanced skin: 41.1 breast: 15.4 Group enriched 6 ASC diff: 71.8;ASC TERT1: 49.4;fHDF/TERT166: 35.9;hTCEpi: 41.4;T-47d: 32.3 +STAMBP AMSH ENSG00000124356 STAM binding protein 2 73828916-73873659 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035800, HPA035801 Uncertain Enhanced Nucleoplasm
Plasma membrane
Cytosol Endometrial cancer:4.70e-5 (unfavourable), Pancreatic cancer:5.79e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.1 Cell line enriched 11 LHCN-M2: 926.0 +NAGK GNK ENSG00000124357 N-acetylglucosamine kinase 2 71064344-71079805 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035206, HPA035207 Enhanced Approved Nucleus
Cytosol Renal cancer:4.35e-4 (unfavourable), Head and neck cancer:5.87e-4 (favourable), Endometrial cancer:6.88e-4 (unfavourable) Expressed in all Expressed in all esophagus: 148.0 Expressed in all +MCEE GLOD2 ENSG00000124370 Methylmalonyl-CoA epimerase 2 71109684-71130239 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035196 Approved Nucleoli Head and neck cancer:4.76e-4 (favourable), Liver cancer:5.78e-4 (favourable) Expressed in all Expressed in all breast: 41.2 Expressed in all +PAIP2B KIAA1155 ENSG00000124374 Poly(A) binding protein interacting protein 2B 2 71182739-71227083 Predicted intracellular proteins Evidence at protein level HPA046784, HPA072371 Approved Approved Cytosol Renal cancer:6.96e-12 (favourable), Endometrial cancer:8.17e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 24.6 Cell line enhanced SCLC-21H: 27.5 +SNRNP27 RY1, U4/U6.U5-27K ENSG00000124380 Small nuclear ribonucleoprotein U4/U6.U5 subunit 27 2 69893560-69905575 Predicted intracellular proteins Evidence at protein level HPA034541 Approved Approved Nucleoplasm Endometrial cancer:2.33e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 43.3 Expressed in all +MPHOSPH10 CT90, MPP10, MPP10P, PPP1R106 ENSG00000124383 M-phase phosphoprotein 10 2 71130314-71150101 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035059, HPA035060, HPA049907 Enhanced Enhanced Nucleoli Renal cancer:3.89e-7 (unfavourable) Expressed in all Expressed in all prostate: 35.3 Expressed in all +IL17C CX2, IL-17C, IL-21, MGC126884, MGC138401 ENSG00000124391 Interleukin 17C 16 88638591-88640473 Predicted secreted proteins Evidence at protein level HPA065051 Supported Mixed Tissue enriched 6 endometrium: 3.5 gallbladder: 0.6 Not detected +ATP8A1 ATPIA ENSG00000124406 ATPase phospholipid transporting 8A1 4 42408373-42657105 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA052935 Enhanced Supported Vesicles Renal cancer:5.54e-10 (favourable) Mixed Tissue enhanced parathyroid gland: 68.8;thyroid gland: 66.6 cerebral cortex: 58.2 Cell line enhanced AN3-CA: 25.5;Daudi: 33.1 +USP22 KIAA1063, USP3L ENSG00000124422 Ubiquitin specific peptidase 22 17 20999593-21043760 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044980 Supported Supported Nuclear speckles Renal cancer:1.53e-7 (favourable), Liver cancer:9.66e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 154.1 Expressed in all +POF1B FLJ22792, POF ENSG00000124429 Premature ovarian failure, 1B X 85277396-85379743 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA002033, HPA050027 Approved Supported Nucleoplasm
Golgi apparatus Liver cancer:2.03e-4 (unfavourable), Endometrial cancer:3.08e-4 (unfavourable) Tissue enhanced Tissue enhanced skin: 144.4 rectum: 52.8 Cell line enhanced A549: 19.6;CAPAN-2: 19.5;HaCaT: 19.9;RT4: 60.9 +HIF3A bHLHe17, IPAS, MOP7, PASD7 ENSG00000124440 Hypoxia inducible factor 3 alpha subunit 19 46297046-46343433 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041141 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Endometrial cancer:6.90e-9 (unfavourable) Mixed Tissue enhanced placenta: 39.8 spleen: 19.9 Cell line enhanced ASC TERT1: 6.5;HHSteC: 16.0;HSkMC: 12.2;TIME: 13.1 +ZNF576 MGC2508 ENSG00000124444 Zinc finger protein 576 19 43596392-43601157 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050064 Uncertain Approved Nucleoplasm
Golgi apparatus Liver cancer:1.29e-4 (unfavourable) Expressed in all Expressed in all prostate: 15.4 Expressed in all +IRGC CINEMA, Iigp5, IRGC1 ENSG00000124449 Immunity related GTPase cinema 19 43716010-43720021 Predicted intracellular proteins Evidence at protein level HPA046769, HPA060064 Enhanced Not detected Tissue enriched 627 testis: 62.6 all non-specific tissues: 0.0 Not detected +ZNF45 ZNF13 ENSG00000124459 Zinc finger protein 45 19 43912629-43935278 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038611, HPA075124 Uncertain Supported Nucleoplasm Expressed in all Mixed parathyroid gland: 18.3 Expressed in all +LYPD3 C4.4A ENSG00000124466 LY6/PLAUR domain containing 3 19 43460787-43465660 Predicted membrane proteins Evidence at protein level HPA041529, HPA041797, HPA077859 Enhanced Approved Endoplasmic reticulum
Vesicles Lung cancer:7.86e-5 (unfavourable) Tissue enhanced Group enriched 6 esophagus: 673.8;skin: 593.4 tonsil: 114.6 Cell line enhanced HaCaT: 85.1;MCF7: 84.1;RT4: 83.0;SK-BR-3: 114.6 +PSG8 ENSG00000124467 Pregnancy specific beta-1-glycoprotein 8 19 42752686-42855691 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046327 Approved Tissue enriched Tissue enriched 12 placenta: 9.1 parathyroid gland: 0.7 Not detected +CEACAM8 CD66b, CGM6 ENSG00000124469 Carcinoembryonic antigen related cell adhesion molecule 8 19 42580241-42595055 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB033676 Approved Not detected Tissue enriched 86 bone marrow: 142.1 lung: 1.6 Not detected +NDP EVR2, norrin ENSG00000124479 NDP, norrin cystine knot growth factor X 43948776-43973504 Disease related genes, Predicted secreted proteins Evidence at protein level HPA003095 Uncertain Supported Nucleus
Nucleoli
Vesicles Tissue enhanced Tissue enhanced ovary: 53.3 fallopian tube: 31.3 Cell line enriched 16 U-87 MG: 67.6 +USP9X DFFRX, FAF, MRX99 ENSG00000124486 Ubiquitin specific peptidase 9, X-linked X 41085635-41236579 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB011618, HPA047417, CAB070164 Approved Uncertain Vesicles Expressed in all Expressed in all parathyroid gland: 90.1 Expressed in all +CRISP2 CRISP-2, CT36, GAPDL5, TPX1 ENSG00000124490 Cysteine rich secretory protein 2 6 49692358-49713590 Predicted secreted proteins Evidence at protein level HPA031248 Enhanced Mixed Tissue enriched 43 testis: 853.2 fallopian tube: 19.7 Not detected +F13A1 F13A ENSG00000124491 Coagulation factor XIII A chain 6 6144085-6321013 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001804, CAB002155 Enhanced Renal cancer:6.61e-6 (unfavourable) Expressed in all Expressed in all placenta: 670.5 Cell line enhanced AF22: 22.5;LHCN-M2: 7.1;RH-30: 41.4 +GRM4 GPRC1D, mGlu4, MGLUR4 ENSG00000124493 Glutamate metabotropic receptor 4 6 34018645-34155622 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB022096 Enhanced Tissue enhanced Tissue enhanced cerebral cortex: 2.9 testis: 0.7 Group enriched 11 BEWO: 7.2;SCLC-21H: 35.0 +TRERF1 BCAR2, dJ139D8.5, HSA277276, RAPA, TReP-132 ENSG00000124496 Transcriptional regulating factor 1 6 42224931-42452051 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027771, HPA051273, HPA059943 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:3.67e-5 (unfavourable) Mixed Mixed testis: 10.9 Cell line enhanced HDLM-2: 133.6 +PACSIN1 SDPI ENSG00000124507 Protein kinase C and casein kinase substrate in neurons 1 6 34466061-34535231 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009929, HPA028852, HPA055491 Enhanced Approved Nucleus
Vesicles Mixed Tissue enriched 32 cerebral cortex: 133.6 lymph node: 4.1 Cell line enhanced MCF7: 9.2;RPMI-8226: 9.7;T-47d: 20.2;U-266/84: 11.7 +BTN2A2 BT2.2, BTF2, BTN2.2 ENSG00000124508 Butyrophilin subfamily 2 member A2 6 26383096-26394874 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA051504 Uncertain Supported Mitochondria Breast cancer:1.01e-4 (favourable) Expressed in all Mixed lymph node: 37.6 Mixed +SIRT5 ENSG00000124523 Sirtuin 5 6 13574529-13615158 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA021798, HPA022002, HPA022992 Approved Enhanced Mitochondria Renal cancer:8.76e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 17.1 Expressed in all +MRS2 MRS2L ENSG00000124532 MRS2, magnesium transporter 6 24402908-24426194 Predicted membrane proteins Evidence at protein level HPA017642 Uncertain Ovarian cancer:5.14e-11 (favourable), Endometrial cancer:5.32e-4 (unfavourable), Thyroid cancer:8.03e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 29.8 Mixed +WRNIP1 bA420G6.2, FLJ22526, WHIP ENSG00000124535 Werner helicase interacting protein 1 6 2765414-2786952 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031752, HPA031753 Enhanced Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 78.7 Expressed in all +RRP36 C6orf153, dJ20C7.4 ENSG00000124541 Ribosomal RNA processing 36 6 43021645-43034156 Predicted intracellular proteins Evidence at protein level HPA029904, HPA029905 Uncertain Supported Nucleus
Nucleoli Renal cancer:2.48e-5 (unfavourable), Liver cancer:5.95e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 61.3 Expressed in all +BTN1A1 BT, BTN, BTN1 ENSG00000124557 Butyrophilin subfamily 1 member A1 6 26501221-26510422 Predicted membrane proteins Evidence at protein level HPA011126, CAB037340 Supported Tissue enhanced Tissue enriched 49 breast: 36.8 lymph node,tonsil: 0.7 Cell line enriched 5 CACO-2: 3.8 +SNRPC U1-C, Yhc1 ENSG00000124562 Small nuclear ribonucleoprotein polypeptide C 6 34757406-34773794 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034338, HPA042419, HPA055490 Supported Enhanced Nucleoplasm Renal cancer:8.20e-5 (unfavourable), Liver cancer:5.65e-4 (unfavourable) Expressed in all Expressed in all testis: 151.1 Expressed in all +SLC17A3 NPT4 ENSG00000124564 Solute carrier family 17 member 3 6 25833066-25882286 Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Tissue enriched 9 kidney: 168.7 liver: 18.6 Cell line enriched 177 RPTEC TERT1: 87.1 +SLC17A1 NAPI-1, NPT1 ENSG00000124568 Solute carrier family 17 member 1 6 25782897-25832059 Predicted membrane proteins, Transporters Evidence at protein level HPA050513 Approved Golgi apparatus Group enriched Tissue enriched 7 kidney: 174.5 liver: 25.1 Cell line enriched 490 RPTEC TERT1: 48.9 +SERPINB6 CAP, DFNB91, PI6, PTI ENSG00000124570 Serpin family B member 6 6 2948159-2972165 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA009668, HPA012736 Enhanced Approved Centrosome Renal cancer:2.21e-4 (unfavourable), Ovarian cancer:4.81e-4 (favourable) Expressed in all Expressed in all testis: 255.6 Mixed +XPO5 KIAA1291 ENSG00000124571 Exportin 5 6 43522330-43576075 Predicted intracellular proteins, Transporters Evidence at protein level CAB012357, HPA018402, HPA023959, HPA029909 Enhanced Enhanced Nucleoplasm Liver cancer:3.98e-8 (unfavourable), Endometrial cancer:4.94e-7 (unfavourable) Expressed in all Expressed in all testis: 43.5 Expressed in all +ABCC10 EST182763, MRP7, SIMRP7 ENSG00000124574 ATP binding cassette subfamily C member 10 6 43427366-43450430 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041607, HPA045464 Approved Renal cancer:1.90e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 12.5 Expressed in all +HIST1H1D H1.3, H1d, H1F3, H1s-2 ENSG00000124575 Histone cluster 1 H1 family member d 6 26234268-26234933 Predicted intracellular proteins Evidence at protein level HPA055907 Approved Mixed Tissue enriched 6 bone marrow: 17.5 lymph node: 2.9 Cell line enhanced BEWO: 6.8;MOLT-4: 9.5;SiHa: 5.0 +PEX6 PAF-2, PXAAA1 ENSG00000124587 Peroxisomal biogenesis factor 6 6 42963870-42979220 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA025924, HPA074179 Enhanced Supported Nucleoplasm
Nuclear bodies
Vesicles Expressed in all Expressed in all fallopian tube: 36.5 Expressed in all +NQO2 DHQV, DIA6, NMOR2, QR2 ENSG00000124588 N-ribosyldihydronicotinamide:quinone reductase 2 6 2987987-3028869 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021283, HPA021332 Enhanced Supported Nucleoplasm
Cytosol Liver cancer:8.40e-4 (unfavourable) Expressed in all Expressed in all kidney: 201.0 Expressed in all +RP11-298J23.10 ENSG00000124593 Prickle-like protein 4 6 41780349-41790141 Predicted intracellular proteins Evidence at transcript level HPA031240 Uncertain Mitotic spindle
Microtubule organizing center Renal cancer:2.47e-4 (unfavourable), Lung cancer:8.24e-4 (favourable) Expressed in all Mixed parathyroid gland: 3.2 Cell line enhanced AF22: 2.3;ASC TERT1: 1.1;HeLa: 1.1;HSkMC: 1.1;TIME: 1.6 +OARD1 C6orf130, dJ34B21.3, MGC19570, TARG1 ENSG00000124596 O-acyl-ADP-ribose deacylase 1 6 41033627-41097787 Predicted intracellular proteins Evidence at protein level HPA029036 Approved Approved Nucleus
Nucleoli Renal cancer:1.13e-4 (favourable) Expressed in all Expressed in all testis: 106.4 Expressed in all +UNC5CL MGC34763, ZUD ENSG00000124602 Unc-5 family C-terminal like 6 41026911-41039217 Predicted intracellular proteins Evidence at protein level HPA015725 Enhanced Approved Centrosome Mixed Tissue enhanced duodenum: 37.3;small intestine: 32.4;stomach: 23.8 kidney: 15.0 Cell line enhanced CACO-2: 5.8;RPTEC TERT1: 10.0 +AARS2 AARSL, bA444E17.1, KIAA1270 ENSG00000124608 Alanyl-tRNA synthetase 2, mitochondrial 6 44299654-44313326 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035636, HPA061396 Approved Enhanced Mitochondria Expressed in all Mixed parathyroid gland: 11.4 Expressed in all +HIST1H1A H1.1, H1a, H1F1 ENSG00000124610 Histone cluster 1 H1 family member a 6 26017085-26017732 Predicted intracellular proteins Evidence at protein level HPA043753 Supported Not detected Not detected testis,thyroid gland: 0.2 Cell line enhanced REH: 1.1;U-2 OS: 1.1 +ZNF391 dJ153G14.3 ENSG00000124613 Zinc finger protein 391 6 27374615-27403904 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA050886 Uncertain Ovarian cancer:1.89e-4 (favourable) Mixed Mixed testis: 9.0 Mixed +RPS10 MGC88819, S10 ENSG00000124614 Ribosomal protein S10 6 34417454-34426125 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047268, HPA048084 Approved Approved Cytosol Renal cancer:2.57e-6 (unfavourable) Expressed in all Expressed in all ovary: 2704.4 Expressed in all +MOCS1 MOCOD ENSG00000124615 Molybdenum cofactor synthesis 1 6 39899578-39934551 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA045783, HPA058177, HPA075505 Uncertain Approved Plasma membrane
Cytosol Cervical cancer:1.07e-5 (unfavourable), Pancreatic cancer:6.07e-5 (favourable) Expressed in all Mixed placenta: 60.3 Cell line enhanced CACO-2: 38.2 +HIST1H2BJ H2B/r, H2BFR ENSG00000124635 Histone cluster 1 H2B family member j 6 27125897-27132750 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Cervical cancer:1.51e-4 (favourable) Expressed in all Tissue enhanced testis: 48.9 prostate: 9.9 Cell line enhanced K-562: 148.0;SiHa: 152.3;U-2 OS: 161.1;U-266/70: 101.2;U-266/84: 122.2 +MED20 DKFZp586D2223, PRO0213, TRFP ENSG00000124641 Mediator complex subunit 20 6 41905354-41921139 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040717 Uncertain Approved Nucleoplasm
Centrosome Melanoma:1.48e-5 (unfavourable), Renal cancer:1.17e-4 (favourable) Expressed in all Expressed in all thyroid gland: 20.8 Expressed in all +OR2B6 dJ408B20.2, OR2B1, OR2B1P, OR2B5, OR2B6P, OR5-40, OR5-41, OR6-31 ENSG00000124657 Olfactory receptor family 2 subfamily B member 6 6 27957241-27958182 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Mixed Not detected testis: 0.3 Cell line enhanced K-562: 1.4;SCLC-21H: 1.5;U-266/84: 2.9;U-937: 1.5 +TBCC CFC ENSG00000124659 Tubulin folding cofactor C 6 42744481-42746096 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035073, HPA035074 Approved Enhanced Cytosol Expressed in all Expressed in all lymph node: 32.8 Expressed in all +SPDEF bA375E1.3, PDEF ENSG00000124664 SAM pointed domain containing ETS transcription factor 6 34537802-34556333 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055707 Supported Nucleus
Nucleoli Endometrial cancer:9.26e-9 (favourable) Group enriched Tissue enhanced prostate: 172.4 breast: 42.6 Cell line enhanced MCF7: 221.8;SK-BR-3: 144.8;T-47d: 145.8 +TCP11 D6S230E, FPPR, KIAA0229 ENSG00000124678 T-complex 11 6 35118071-35148610 Predicted intracellular proteins Evidence at protein level HPA048311 Supported Cervical cancer:5.02e-4 (favourable) Tissue enhanced Tissue enriched 356 testis: 562.3 fallopian tube: 1.5 Cell line enhanced hTEC/SVTERT24-B: 1.6;WM-115: 2.0 +MAD2L1BP CMT2, dJ261G23.1, KIAA0110 ENSG00000124688 MAD2L1 binding protein 6 43629540-43640952 Predicted intracellular proteins Evidence at protein level HPA028729 Supported Nucleus
Nuclear membrane
Nucleoli Expressed in all Expressed in all bone marrow: 32.6 Expressed in all +APOBEC2 ARCD1, ARP1 ENSG00000124701 Apolipoprotein B mRNA editing enzyme catalytic subunit 2 6 41053304-41064511 Enzymes, Predicted intracellular proteins Evidence at protein level HPA014252, HPA017957 Enhanced Tissue enhanced Group enriched 13 heart muscle: 120.7;skeletal muscle: 403.8 esophagus: 19.5 Cell line enhanced CACO-2: 3.3 +KLHDC3 dJ20C7.3, hPeas, PEAS ENSG00000124702 Kelch domain containing 3 6 43014103-43021298 Predicted intracellular proteins Evidence at protein level HPA030131, HPA030132, HPA030133, HPA030134 Uncertain Supported Nucleoplasm Endometrial cancer:4.52e-4 (unfavourable), Pancreatic cancer:9.08e-4 (favourable), Cervical cancer:9.15e-4 (favourable) Expressed in all Expressed in all testis: 251.9 Expressed in all +GNMT ENSG00000124713 Glycine N-methyltransferase 6 42960758-42963880 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027501 Enhanced Approved Cytosol Liver cancer:1.86e-4 (favourable) Group enriched Group enriched 9 liver: 155.0;pancreas: 55.8;prostate: 32.7 breast: 9.4 Cell line enhanced Hep G2: 5.7;SCLC-21H: 11.3;T-47d: 5.8 +DNAH8 hdhc9 ENSG00000124721 Dynein axonemal heavy chain 8 6 38715341-39030529 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028447 Uncertain Tissue enriched Tissue enhanced testis: 14.3 prostate: 3.4 Cell line enriched 8 HMC-1: 41.4 +TREM1 CD354, TREM-1 ENSG00000124731 Triggering receptor expressed on myeloid cells 1 6 41267926-41286719 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005563 Uncertain Tissue enhanced Tissue enhanced appendix: 67.7;bone marrow: 63.0;lung: 103.1 adipose tissue: 26.9 Cell line enriched 11 U-87 MG: 24.5 +MEA1 MEA ENSG00000124733 Male-enhanced antigen 1 6 43012094-43013968 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017921 Approved Approved Nucleus
Cytosol Renal cancer:1.29e-6 (unfavourable), Ovarian cancer:3.37e-4 (favourable) Expressed in all Expressed in all testis: 246.1 Expressed in all +KLHL31 bA345L23.2, BKLHD6, KBTBD1 ENSG00000124743 Kelch like family member 31 6 53647901-53665708 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced heart muscle: 29.4;skeletal muscle: 51.2 adipose tissue: 9.0 Cell line enhanced SCLC-21H: 1.2 +COL21A1 ENSG00000124749 Collagen type XXI alpha 1 chain 6 56056590-56394094 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031212 Supported Cytosol Mixed Tissue enhanced cervix, uterine: 36.7;placenta: 39.0 endometrium: 19.6 Cell line enhanced ASC TERT1: 15.7;BEWO: 7.2;HSkMC: 16.7 +CDKN1A CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1 ENSG00000124762 Cyclin dependent kinase inhibitor 1A 6 36676460-36687339 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB000064, HPA005946, CAB069401 Supported Supported Nucleoplasm
Nuclear bodies Endometrial cancer:3.14e-5 (favourable), Renal cancer:4.95e-5 (favourable), Lung cancer:7.05e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 204.8 Cell line enhanced HHSteC: 654.9 +SOX4 ENSG00000124766 SRY-box 4 6 21592768-21598619 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029901 Approved Supported Nucleoplasm
Mitochondria Liver cancer:2.57e-5 (unfavourable) Expressed in all Expressed in all endometrium: 80.5 Cell line enhanced AN3-CA: 194.4;MOLT-4: 151.8;SH-SY5Y: 123.8 +GLO1 GLOD1 ENSG00000124767 Glyoxalase I 6 38675925-38703141 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB040541, CAB040542, HPA059791 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:5.21e-4 (unfavourable) Expressed in all Expressed in all prostate: 274.2 Cell line enriched 5 HMC-1: 2266.7 +CPNE5 COPN5, CPN5, KIAA1599 ENSG00000124772 Copine 5 6 36740775-36840002 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031369 Uncertain Approved Cytosol Head and neck cancer:2.87e-5 (favourable), Renal cancer:6.00e-5 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 119.0 testis: 34.4 Cell line enhanced Daudi: 42.5;HUVEC TERT2: 19.9;U-266/70: 15.0;U-266/84: 11.9;U-698: 19.2 +KCNK17 K2p17.1, TALK-2, TALK2, TASK-4, TASK4 ENSG00000124780 Potassium two pore domain channel subfamily K member 17 6 39299001-39314553 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at transcript level HPA043892 Uncertain Mixed Tissue enhanced lung: 5.6 placenta: 5.3 Cell line enriched 9 SCLC-21H: 91.6 +RREB1 HNT ENSG00000124782 Ras responsive element binding protein 1 6 7107597-7251980 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001756, HPA034843 Approved Supported Nucleoli fibrillar center
Nuclear speckles Renal cancer:1.41e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 23.1 Mixed +SSR1 TRAPA ENSG00000124783 Signal sequence receptor subunit 1 6 7268306-7347446 Predicted membrane proteins Evidence at protein level HPA011276, HPA017062 Enhanced Supported Endoplasmic reticulum Renal cancer:5.79e-6 (unfavourable), Liver cancer:4.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 141.0 Expressed in all +RIOK1 AD034, bA288G3.1, FLJ30006, RRP10 ENSG00000124784 RIO kinase 1 6 7389496-7418037 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017866, HPA051446 Enhanced Approved Nucleoli
Nuclear speckles
Cytosol Liver cancer:3.41e-5 (unfavourable), Renal cancer:5.85e-5 (unfavourable), Melanoma:4.43e-4 (unfavourable) Expressed in all Expressed in all testis: 29.6 Expressed in all +NRN1 NRN ENSG00000124785 Neuritin 1 6 5997999-6007605 Predicted membrane proteins Evidence at protein level Renal cancer:4.79e-5 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 152.5 adipose tissue: 61.5 Cell line enhanced fHDF/TERT166: 111.6;REH: 174.8 +SLC35B3 C6orf196, CGI-19, dJ453H5.1, PAPST2 ENSG00000124786 Solute carrier family 35 member B3 6 8413068-8435483 Predicted membrane proteins, Transporters Evidence at protein level HPA054661, HPA057801 Approved Expressed in all Expressed in all epididymis: 63.2 Expressed in all +RPP40 bA428J1.3, RNASEP1 ENSG00000124787 Ribonuclease P/MRP subunit p40 6 4994732-5004063 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035685, HPA035686 Uncertain Approved Nucleoplasm Renal cancer:7.54e-8 (unfavourable), Endometrial cancer:6.10e-6 (unfavourable), Liver cancer:5.41e-4 (unfavourable) Expressed in all Mixed adrenal gland: 11.9 Expressed in all +ATXN1 ATX1, D6S504E, SCA1 ENSG00000124788 Ataxin 1 6 16299112-16761491 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008335, HPA070756 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all cerebral cortex: 17.5 Cell line enhanced U-266/70: 22.6 +NUP153 HNUP153 ENSG00000124789 Nucleoporin 153 6 17615035-17706834 Predicted intracellular proteins, Transporters Evidence at protein level HPA027896, HPA027897, HPA027898 Enhanced Enhanced Nuclear membrane Expressed in all Expressed in all testis: 53.6 Expressed in all +DEK D6S231E ENSG00000124795 DEK proto-oncogene 6 18223868-18264823 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015226, HPA054505, HPA057799 Enhanced Enhanced Nucleus Renal cancer:3.45e-4 (unfavourable), Liver cancer:9.65e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 158.8 Mixed +EEF1E1 AIMP3, P18 ENSG00000124802 Eukaryotic translation elongation factor 1 epsilon 1 6 8073360-8102578 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027901, HPA057866 Approved Supported Nucleus
Cytosol Liver cancer:1.55e-7 (unfavourable), Cervical cancer:3.16e-4 (favourable), Ovarian cancer:3.24e-4 (favourable) Expressed in all Expressed in all testis: 101.7 Expressed in all +CRISP1 AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP ENSG00000124812 Cysteine rich secretory protein 1 6 49834257-49877096 Predicted secreted proteins Evidence at protein level HPA028445, HPA030534 Enhanced Not detected Tissue enriched 20 epididymis: 1915.6 seminal vesicle: 96.7 Cell line enhanced NB-4: 1.7 +RUNX2 AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1 ENSG00000124813 Runt related transcription factor 2 6 45328157-45664349 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB008374, HPA022040, CAB062561, CAB068226 Enhanced Enhanced Nucleoplasm Renal cancer:3.97e-9 (unfavourable), Urothelial cancer:6.66e-5 (unfavourable), Stomach cancer:2.24e-4 (unfavourable) Mixed Mixed cervix, uterine: 10.6 Cell line enhanced Karpas-707: 54.6;RH-30: 54.1;U-698: 41.3 +OPN5 dJ402H5.1, neuropsin, TMEM13 ENSG00000124818 Opsin 5 6 47781982-47832780 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA026084 Supported Not detected Tissue enriched 36 testis: 4.1 heart muscle: 0.1 Not detected +GCM2 GCMB, hGCMb ENSG00000124827 Glial cells missing homolog 2 6 10873223-10881941 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Tissue enriched 997 parathyroid gland: 774.1 testis: 0.7 Not detected +LRRFIP1 FLAP-1, FLIIAP1, GCF-2, HUFI-1, TRIP ENSG00000124831 LRR binding FLII interacting protein 1 2 237627576-237813682 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006979 Approved Supported Cytosol Expressed in all Expressed in all parathyroid gland: 125.3 Expressed in all +RAB17 ENSG00000124839 RAB17, member RAS oncogene family 2 237574322-237601614 Predicted intracellular proteins Evidence at protein level HPA035176 Approved Renal cancer:3.33e-13 (favourable), Urothelial cancer:2.51e-4 (favourable), Pancreatic cancer:4.14e-4 (favourable) Mixed Mixed small intestine: 64.3 Cell line enhanced BEWO: 40.2;MCF7: 36.3;SK-BR-3: 37.2;SK-MEL-30: 95.1 +CXCL6 CKA-3, GCP-2, SCYB6 ENSG00000124875 C-X-C motif chemokine ligand 6 4 73836497-73849064 Predicted secreted proteins Evidence at protein level Renal cancer:4.82e-4 (unfavourable) Mixed Tissue enhanced gallbladder: 50.3;spleen: 112.9 urinary bladder: 32.4 Group enriched 6 BJ hTERT+: 36.7;EFO-21: 100.3;hTEC/SVTERT24-B: 22.6;HUVEC TERT2: 59.0;RPTEC TERT1: 62.9 +EREG ER ENSG00000124882 Epiregulin 4 74365143-74388751 Predicted membrane proteins Evidence at protein level HPA054373 Approved Vesicles Cervical cancer:1.67e-7 (unfavourable), Lung cancer:1.45e-5 (unfavourable), Pancreatic cancer:6.57e-5 (unfavourable) Tissue enhanced Tissue enriched 6 bone marrow: 82.3 appendix: 14.4 Cell line enhanced BJ hTERT+: 218.4;U-2197: 168.6;U-87 MG: 300.8 +TRIM51 SPRYD5, TRIM51A ENSG00000124900 Tripartite motif-containing 51 11 55883297-55891810 Predicted intracellular proteins Evidence at transcript level HPA044988, HPA077883 Uncertain Approved Nucleoli
Vesicles Tissue enriched Not detected testis: 0.4 Group enriched 101 SK-MEL-30: 45.9;WM-115: 14.6 +MYRF C11orf9, MRF, Ndt80, pqn-47 ENSG00000124920 Myelin regulatory factor 11 61752642-61788518 Plasma proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA018310 Approved Nucleoplasm
Cytosol Renal cancer:2.01e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 67.4;stomach: 62.1 gallbladder: 38.3 Cell line enhanced A549: 36.8;CACO-2: 56.7;CAPAN-2: 34.1;EFO-21: 48.7 +SCGB1D2 LIPB, LPHB ENSG00000124935 Secretoglobin family 1D member 2 11 62242210-62244808 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA035318 Approved Endometrial cancer:3.46e-6 (favourable), Renal cancer:8.03e-6 (favourable) Group enriched Group enriched 9 breast: 1446.3;cervix, uterine: 5193.3 epididymis: 385.3 Cell line enriched 7 SCLC-21H: 11.2 +SCGB2A1 LPHC, MGB2, MGC71973, UGB3 ENSG00000124939 Secretoglobin family 2A member 1 11 62208668-62213939 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA034584 Enhanced Endometrial cancer:1.54e-8 (favourable), Colorectal cancer:1.22e-4 (favourable), Renal cancer:6.36e-4 (favourable) Group enriched Group enriched 6 cervix, uterine: 2863.6;epididymis: 1665.3 fallopian tube: 381.7 Cell line enhanced EFO-21: 8.1;NB-4: 1.3;SCLC-21H: 1.9 +AHNAK MGC5395 ENSG00000124942 AHNAK nucleoprotein 11 62433542-62556235 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019010, HPA019070, HPA026643 Uncertain Supported Plasma membrane
Cytosol Urothelial cancer:3.47e-6 (unfavourable), Pancreatic cancer:2.42e-4 (unfavourable) Expressed in all Expressed in all skin: 397.0 Mixed +EMC3 TMEM111 ENSG00000125037 ER membrane protein complex subunit 3 3 9962537-10011116 Predicted membrane proteins Evidence at protein level HPA042372 Approved Approved Microtubules
Cytosol Renal cancer:2.81e-6 (favourable) Expressed in all Expressed in all testis: 90.8 Expressed in all +SSUH2 C3orf32, fls485, ssu-2 ENSG00000125046 Ssu-2 homolog (C. elegans) 3 8619400-8745040 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049777 Approved Mixed Tissue enhanced duodenum: 4.2;small intestine: 3.9;testis: 4.0 spleen: 1.5 Cell line enriched 13 Hep G2: 18.2 +WNT1 INT1 ENSG00000125084 Wnt family member 1 12 48978453-48981676 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level Not detected Tissue enhanced cerebral cortex: 1.3 lymph node: 1.0 Not detected +SH3TC1 FLJ20356 ENSG00000125089 SH3 domain and tetratricopeptide repeats 1 4 8182072-8241803 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038132, HPA056807 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all Mixed spleen: 12.5 Cell line enhanced HUVEC TERT2: 20.1;MOLT-4: 35.0;SK-MEL-30: 19.0 +CNOT1 AD-005, CDC39, KIAA1007, NOT1, NOT1H ENSG00000125107 CCR4-NOT transcription complex subunit 1 16 58519951-58629886 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046577, HPA049664 Approved Supported Cytosol Expressed in all Expressed in all testis: 196.3 Expressed in all +LRRC29 FBL9, FBXL9 ENSG00000125122 Leucine rich repeat containing 29 16 67207139-67227048 Predicted intracellular proteins Evidence at protein level HPA034998 Uncertain Uncertain Nucleoplasm Endometrial cancer:4.33e-4 (favourable), Pancreatic cancer:5.20e-4 (favourable) Expressed in all Mixed thyroid gland: 1.8 Mixed +BBS2 BBS ENSG00000125124 Bardet-Biedl syndrome 2 16 56466836-56520283 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041315 Approved Renal cancer:2.83e-6 (favourable) Expressed in all Expressed in all adrenal gland: 91.3 Expressed in all +MT1G MT1, MT1K ENSG00000125144 Metallothionein 1G 16 56666731-56668065 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.67e-7 (unfavourable) Expressed in all Tissue enhanced kidney: 2350.1;thyroid gland: 4892.2 liver: 1276.9 Cell line enriched 5 U-937: 867.7 +MT2A MT2 ENSG00000125148 Metallothionein 2A 16 56608199-56609497 Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:2.92e-9 (unfavourable), Lung cancer:5.74e-5 (unfavourable), Pancreatic cancer:9.52e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 1202.2 Cell line enhanced HBEC3-KT: 6860.6;LHCN-M2: 3182.4;U-87 MG: 3004.5 +C16orf70 C16orf6, FLJ12076, lin-10, LIN10 ENSG00000125149 Chromosome 16 open reading frame 70 16 67109958-67148539 Predicted intracellular proteins Evidence at protein level HPA041131, HPA041214 Approved Approved Nuclear speckles
Cytosol Expressed in all Expressed in all parathyroid gland: 33.3 Expressed in all +GOT2 KAT4, KATIV, KYAT4, mitAAT ENSG00000125166 Glutamic-oxaloacetic transaminase 2 16 58707131-58734357 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA018139 Enhanced Renal cancer:2.90e-9 (favourable), Liver cancer:5.75e-5 (favourable), Head and neck cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 240.2 Expressed in all +DOK4 FLJ10488 ENSG00000125170 Docking protein 4 16 57471922-57487327 Predicted intracellular proteins Evidence at protein level HPA055849 Supported Approved Vesicles
Microtubules
Cytokinetic bridge Expressed in all Expressed in all small intestine: 54.7 Cell line enhanced SH-SY5Y: 254.2 +PIWIL1 CT80.1, HIWI, PIWI ENSG00000125207 Piwi like RNA-mediated gene silencing 1 12 130337887-130372637 Predicted intracellular proteins Evidence at protein level CAB012217, HPA018798 Enhanced Tissue enhanced Tissue enriched 34 testis: 5.2 cervix, uterine,duodenum,spleen: 0.1 Cell line enhanced CAPAN-2: 2.3 +GPR18 ENSG00000125245 G protein-coupled receptor 18 13 99254714-99261744 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013873 Enhanced Mixed Tissue enhanced lymph node: 51.5;testis: 25.3;tonsil: 31.5 appendix: 16.4 Cell line enhanced Daudi: 6.1;THP-1: 13.5;U-937: 2.6 +CLYBL CLB ENSG00000125246 Citrate lyase beta like 13 99606669-99897134 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039959, HPA040691 Enhanced Approved Cytosol Renal cancer:6.66e-16 (favourable) Expressed in all Expressed in all kidney: 67.5 Cell line enhanced SCLC-21H: 62.6 +TMTC4 FLJ14624, FLJ22153 ENSG00000125247 Transmembrane and tetratricopeptide repeat containing 4 13 100603927-100675093 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016489 Uncertain Approved Vesicles Expressed in all Expressed in all cerebral cortex: 26.4 Mixed +RAP2A K-REV, RAP2 ENSG00000125249 RAP2A, member of RAS oncogene family 13 97434222-97469128 Predicted intracellular proteins Evidence at protein level CAB018552 Uncertain Liver cancer:1.55e-4 (unfavourable), Renal cancer:8.06e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 74.9 Expressed in all +SLC10A2 ASBT, ISBT ENSG00000125255 Solute carrier family 10 member 2 13 103043998-103066846 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA004795 Approved Renal cancer:5.78e-5 (favourable) Tissue enriched Group enriched 31 duodenum: 21.0;kidney: 15.4;small intestine: 51.4 gallbladder: 0.9 Not detected +ABCC4 EST170205, MOAT-B, MOATB, MRP4 ENSG00000125257 ATP binding cassette subfamily C member 4 13 95019829-95301446 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA002476 Enhanced Renal cancer:2.25e-10 (favourable), Endometrial cancer:9.89e-4 (unfavourable) Tissue enriched Tissue enhanced prostate: 70.4 epididymis: 23.6 Group enriched 5 HEL: 277.0;HMC-1: 278.6 +EFNB2 EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228 ENSG00000125266 Ephrin B2 13 106489731-106535114 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA008999, CAB009368 Supported Supported Nucleoplasm
Cytosol Head and neck cancer:3.11e-6 (unfavourable), Pancreatic cancer:8.70e-5 (unfavourable), Lung cancer:8.43e-4 (unfavourable) Expressed in all Mixed placenta: 48.4 Cell line enhanced AF22: 180.7;SH-SY5Y: 87.9 +SOX21 SOX25 ENSG00000125285 SRY-box 21 13 94709622-94712399 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA048337, HPA064084 Approved Approved Nucleus Glioma:1.34e-4 (favourable), Cervical cancer:7.60e-4 (favourable) Tissue enhanced Group enriched 6 cerebral cortex: 17.9;esophagus: 6.9;skin: 19.4;stomach: 33.4 tonsil: 3.1 Cell line enhanced AF22: 80.6;HAP1: 12.8;NTERA-2: 22.0;PC-3: 11.6 +TM9SF2 P76 ENSG00000125304 Transmembrane 9 superfamily member 2 13 99501417-99564006 Predicted membrane proteins, Transporters Evidence at protein level HPA005657 Supported Renal cancer:5.21e-7 (favourable), Head and neck cancer:6.40e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 202.1 Expressed in all +C17orf53 MGC3130 ENSG00000125319 Chromosome 17 open reading frame 53 17 44141906-44162476 Predicted intracellular proteins Evidence at protein level HPA023004, HPA023393, HPA024430 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:3.46e-4 (unfavourable), Endometrial cancer:8.08e-4 (unfavourable), Lung cancer:9.39e-4 (unfavourable) Mixed Tissue enhanced testis: 12.5 bone marrow: 6.3 Mixed +KIF25 KNSL3 ENSG00000125337 Kinesin family member 25 6 167996241-168045089 Predicted intracellular proteins Evidence at protein level HPA046153 Uncertain Tissue enhanced Tissue enriched 5 adipose tissue: 8.7 placenta: 1.6 Cell line enhanced HDLM-2: 1.1;U-937: 1.3;WM-115: 1.0 +IRF1 MAR ENSG00000125347 Interferon regulatory factor 1 5 132481609-132490798 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB011662, HPA063131 Supported Supported Nucleoplasm
Cytosol Renal cancer:1.09e-7 (unfavourable) Expressed in all Expressed in all spleen: 135.0 Expressed in all +UPF3B HUPF3B, MRX62, RENT3B, UPF3BP1, UPF3BP2, UPF3BP3, UPF3X ENSG00000125351 UPF3 regulator of nonsense transcripts homolog B (yeast) X 119805311-119852998 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001592, HPA001800, HPA001882 Approved Enhanced Nucleus
Nucleoli
Cytosol Renal cancer:1.44e-7 (unfavourable), Liver cancer:1.52e-6 (unfavourable), Melanoma:5.39e-4 (unfavourable) Expressed in all Expressed in all testis: 23.9 Expressed in all +RNF113A Cwc24, RNF113, ZNF183 ENSG00000125352 Ring finger protein 113A X 119870475-119871827 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000160, HPA076658 Approved Approved Nucleoplasm Urothelial cancer:6.23e-4 (favourable), Renal cancer:7.93e-4 (unfavourable) Expressed in all Expressed in all lymph node: 24.5 Expressed in all +SEPT6 KIAA0128, MGC16619, MGC20339, SEP2, SEPT2 ENSG00000125354 Septin 6 X 119615724-119693370 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003459, HPA005665 Supported Approved Cytosol Expressed in all Mixed lymph node: 140.7 Cell line enhanced MOLT-4: 239.1;REH: 246.9;SH-SY5Y: 417.7 +TMEM255A FAM70A, FLJ20716 ENSG00000125355 Transmembrane protein 255A X 120258650-120311556 Predicted membrane proteins, Transporters Evidence at transcript level HPA048470 Uncertain Uncertain Nucleus
Nuclear bodies Group enriched Tissue enhanced ovary: 23.5 cervix, uterine: 10.5 Cell line enhanced Karpas-707: 18.2;RPMI-8226: 11.7;SK-MEL-30: 21.1;U-2 OS: 11.8;U-87 MG: 27.9 +NDUFA1 CI-MWFE, MWFE ENSG00000125356 NADH:ubiquinone oxidoreductase subunit A1 X 119871487-119876662 Disease related genes, Predicted membrane proteins Evidence at protein level HPA029768, HPA054359 Enhanced Supported Mitochondria
Cytosol Renal cancer:3.48e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 224.8 Expressed in all +AMELX AIH1, AMG ENSG00000125363 Amelogenin, X-linked X 11293413-11300761 Disease related genes, Predicted secreted proteins Evidence at protein level Tissue enhanced Not detected epididymis: 0.4 Not detected +ATP5S ATPW, HSU79253 ENSG00000125375 ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 14 50312326-50335558 Predicted intracellular proteins Evidence at protein level HPA046967, HPA062690 Approved Approved Nucleoplasm
Mitochondria Renal cancer:2.37e-8 (favourable), Lung cancer:5.53e-4 (favourable) Expressed in all Mixed skin: 8.4 Mixed +BMP4 BMP2B ENSG00000125378 Bone morphogenetic protein 4 14 53949736-53958761 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB006863, HPA066235 Enhanced Expressed in all Mixed placenta: 64.1 Cell line enhanced CACO-2: 100.3;CAPAN-2: 262.8;Hep G2: 222.2;U-2 OS: 93.4 +PTGER2 EP2 ENSG00000125384 Prostaglandin E receptor 2 14 52314305-52328606 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Renal cancer:4.16e-4 (unfavourable) Mixed Mixed cervix, uterine: 27.3 Cell line enhanced ASC TERT1: 50.0;HHSteC: 38.3;HSkMC: 41.8 +FAM193A C4orf8, RES4-22 ENSG00000125386 Family with sequence similarity 193 member A 4 2536631-2732565 Predicted intracellular proteins Evidence at protein level HPA043116 Approved Approved Plasma membrane
Cytosol Pancreatic cancer:4.80e-4 (favourable) Expressed in all Expressed in all testis: 30.2 Expressed in all +GRK4 GPRK2L, GPRK4 ENSG00000125388 G protein-coupled receptor kinase 4 4 2963608-3040747 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028737, HPA057023 Approved Supported Vesicles Expressed in all Tissue enriched 9 testis: 74.7 cerebral cortex: 8.1 Cell line enhanced SCLC-21H: 18.6 +SOX9 CMD1, CMPD1, SRA1 ENSG00000125398 SRY-box 9 17 72121020-72126420 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001758, CAB022456, CAB068240 Enhanced Enhanced Nucleoplasm Lung cancer:2.07e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 61.3 Cell line enhanced AN3-CA: 72.2;Hep G2: 65.5;U-251 MG: 54.6 +TEKT3 FLJ32828 ENSG00000125409 Tektin 3 17 15303811-15341641 Predicted intracellular proteins Evidence at protein level HPA044354 Uncertain Mixed Tissue enriched 6 testis: 46.1 fallopian tube: 7.5 Cell line enhanced HMC-1: 1.3 +MYH2 IBM3, MYH2A, MYHas8, MyHC-2A, MyHC-IIa, MYHSA2 ENSG00000125414 Myosin heavy chain 2 17 10521148-10549957 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001349, CAB010760 Enhanced Tissue enriched Tissue enriched 100 skeletal muscle: 4306.1 esophagus: 43.2 Cell line enhanced fHDF/TERT166: 3.1;HSkMC: 1.3;NTERA-2: 8.3 +HS3ST3B1 30ST3B1, 3OST3B1 ENSG00000125430 Heparan sulfate-glucosamine 3-sulfotransferase 3B1 17 14301083-14349404 Enzymes, Predicted intracellular proteins Evidence at protein level HPA064126 Approved Vesicles Mixed Tissue enhanced liver: 14.7 lymph node: 7.1 Cell line enhanced AF22: 20.5;BEWO: 14.3;HSkMC: 14.6;U-251 MG: 16.3 +SLC25A35 FLJ40217 ENSG00000125434 Solute carrier family 25 member 35 17 8287763-8295343 Predicted membrane proteins, Transporters Evidence at protein level HPA051720 Uncertain Approved Vesicles
Mitochondria Endometrial cancer:3.37e-7 (favourable), Renal cancer:1.14e-6 (favourable), Urothelial cancer:1.91e-5 (favourable) Expressed in all Mixed testis: 19.3 Mixed +MRPS7 MRP-S, RP-S7, RPMS7 ENSG00000125445 Mitochondrial ribosomal protein S7 17 75261674-75266373 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA022522, HPA023007 Supported Approved Mitochondria Colorectal cancer:1.12e-4 (favourable), Liver cancer:3.13e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 60.8 Expressed in all +GGA3 KIAA0154 ENSG00000125447 Golgi associated, gamma adaptin ear containing, ARF binding protein 3 17 75236599-75262363 Predicted intracellular proteins Evidence at protein level HPA022945, HPA024645 Approved Supported Golgi apparatus Liver cancer:2.77e-6 (unfavourable), Renal cancer:3.41e-4 (unfavourable), Endometrial cancer:8.26e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.7 Expressed in all +ARMC7 FLJ22160 ENSG00000125449 Armadillo repeat containing 7 17 75109952-75130265 Predicted intracellular proteins Evidence at protein level HPA024229, HPA053076 Uncertain Supported Cytosol Liver cancer:2.24e-5 (unfavourable), Renal cancer:1.27e-4 (favourable), Cervical cancer:2.98e-4 (favourable) Expressed in all Expressed in all lung: 12.6 Expressed in all +NUP85 FLJ12549, NUP75 ENSG00000125450 Nucleoporin 85 17 75205659-75235758 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA061910, HPA062595 Enhanced Supported Nucleus
Cytosol Liver cancer:1.73e-7 (unfavourable), Renal cancer:3.32e-6 (unfavourable) Expressed in all Expressed in all testis: 33.6 Expressed in all +SLC25A19 DNC, MCPHA, MUP1, TPC ENSG00000125454 Solute carrier family 25 member 19 17 75272981-75289510 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Liver cancer:1.21e-7 (unfavourable), Endometrial cancer:8.72e-5 (unfavourable) Expressed in all Expressed in all testis: 49.2 Expressed in all +MIF4GD AD023, MGC45027, MIFD, SLIP1 ENSG00000125457 MIF4G domain containing 17 75266228-75271227 Predicted intracellular proteins Evidence at protein level HPA051222 Approved Supported Nucleoli
Cytosol Pancreatic cancer:2.70e-4 (favourable) Expressed in all Expressed in all lymph node: 45.8 Expressed in all +NT5C cdN, DNT-1, DNT1, PN-I, UMPH2 ENSG00000125458 5', 3'-nucleotidase, cytosolic 17 75130225-75131795 Predicted intracellular proteins Evidence at protein level HPA021581, HPA023632 Approved Supported Cytosol Liver cancer:3.05e-4 (unfavourable), Urothelial cancer:7.66e-4 (favourable) Expressed in all Expressed in all small intestine: 31.3 Expressed in all +MSTO1 FLJ10504, LST005, misato, MST ENSG00000125459 Misato 1, mitochondrial distribution and morphology regulator 1 155610205-155614967 Predicted intracellular proteins Evidence at protein level HPA005899, HPA005914 Approved Approved Nuclear membrane
Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.90e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 24.9 Expressed in all +C1orf61 CROC4 ENSG00000125462 Chromosome 1 open reading frame 61 1 156404250-156430701 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 129 cerebral cortex: 504.3 testis: 3.9 Cell line enriched 9 BEWO: 12.5 +TTF1 ENSG00000125482 Transcription termination factor 1 9 132375548-132406851 Predicted intracellular proteins Evidence at protein level HPA054837 Supported Supported Nucleus
Nucleoli Liver cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 18.2 Expressed in all +GTF3C4 KAT12, TFIIIC90 ENSG00000125484 General transcription factor IIIC subunit 4 9 132670035-132694955 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069369 Supported Nucleus Renal cancer:2.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.0 Expressed in all +DDX31 FLJ13633, FLJ14578, FLJ23349, PPP1R25 ENSG00000125485 DEAD-box helicase 31 9 132592997-132670401 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020891 Supported Nucleoli
Golgi apparatus
Vesicles Liver cancer:1.68e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 23.0 Expressed in all +BARHL1 ENSG00000125492 BarH like homeobox 1 9 132582185-132590266 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA004809 Approved Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 154 SCLC-21H: 19.7 +KIR2DL1 47.11, CD158A, cl-42, nkat1, p58.1 ENSG00000125498 Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 19 54769811-54784322 CD markers, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +PPP1R12C DKFZP434D0412, LENG3, MBS85, p84, p85 ENSG00000125503 Protein phosphatase 1 regulatory subunit 12C 19 55090913-55117559 Predicted intracellular proteins Evidence at protein level HPA043532 Approved Pancreatic cancer:4.10e-5 (favourable) Expressed in all Expressed in all endometrium: 112.5 Expressed in all +MBOAT7 BB1, hMBOA-7, LENG4, LPIAT ENSG00000125505 Membrane bound O-acyltransferase domain containing 7 19 54173412-54189882 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA055967 Approved Approved Cytosol Liver cancer:5.55e-6 (unfavourable), Renal cancer:6.62e-5 (unfavourable), Urothelial cancer:4.31e-4 (favourable), Lung cancer:5.13e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 24.3 Cell line enhanced HMC-1: 150.7 +SRMS C20orf148, dJ697K14.1, PTK70, SRM ENSG00000125508 Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 20 63540810-63547504 Enzymes, Predicted intracellular proteins Evidence at protein level CAB044668, CAB044669, HPA073987 Uncertain Approved Intermediate filaments
Actin filaments
Cytosol Mixed Mixed stomach: 1.4 Cell line enhanced CAPAN-2: 2.9;MCF7: 2.2;RT4: 4.8 +OPRL1 KOR-3, NOCIR, NOPr, OOR, ORL1 ENSG00000125510 Opioid related nociceptin receptor 1 20 64080173-64100643 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 12.3 testis: 4.7 Cell line enhanced REH: 4.4;SCLC-21H: 9.4;U-937: 7.1 +SLC2A4RG GEF, HDBP1, Si-1-2, Si-1-2-19 ENSG00000125520 SLC2A4 regulator 20 63739861-63743505 Predicted intracellular proteins Evidence at protein level HPA063050 Approved Nuclear speckles Expressed in all Expressed in all adipose tissue: 53.7 Expressed in all +NPBWR2 GPR8 ENSG00000125522 Neuropeptides B and W receptor 2 20 64105820-64107171 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Not detected Not detected adrenal gland,cerebral cortex: 0.1 Not detected +FNDC11 C20orf195, MGC5356 ENSG00000125531 Fibronectin type III domain containing 11 20 63547891-63556708 Predicted intracellular proteins Evidence at protein level HPA041341 Approved Nucleoplasm
Vesicles
Aggresome Mixed Tissue enriched 19 testis: 53.0 epididymis: 2.8 Cell line enhanced CAPAN-2: 4.5;EFO-21: 2.5;SH-SY5Y: 3.4 +BHLHE23 bA305P22.3, Beta4, BHLHB4, bHLHe23 ENSG00000125533 Basic helix-loop-helix family member e23 20 63005927-63007035 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA030575 Uncertain Tissue enriched Not detected testis: 0.1 Cell line enriched 22 MOLT-4: 10.3 +PPDPF C20orf149, dJ697K14.9, exdpf ENSG00000125534 Pancreatic progenitor cell differentiation and proliferation factor 20 63520724-63522206 Predicted intracellular proteins Evidence at protein level HPA040929 Approved Nucleoplasm
Nucleoli
Microtubules Renal cancer:3.91e-4 (favourable) Expressed in all Expressed in all stomach: 210.2 Mixed +IL1B IL-1B, IL1-BETA, IL1F2 ENSG00000125538 Interleukin 1 beta 2 112829751-112836903 Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:7.49e-5 (unfavourable), Cervical cancer:1.31e-4 (unfavourable) Mixed Tissue enhanced appendix: 68.0;bone marrow: 106.4 adipose tissue: 53.4 Cell line enhanced BJ hTERT+: 478.0;HBEC3-KT: 193.4;HMC-1: 189.1;hTEC/SVTERT24-B: 291.2;U-87 MG: 514.6 +PLGLB2 PLGP1 ENSG00000125551 Plasminogen-like B2 2 87748087-87758793 Predicted secreted proteins Evidence at transcript level HPA053770 Approved Vesicles Tissue enriched Tissue enriched 161 liver: 245.3 skin: 1.5 Mixed +IL37 FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7 ENSG00000125571 Interleukin 37 2 112912971-112918882 Predicted intracellular proteins Evidence at protein level HPA054371, HPA057950 Approved Supported Nucleoplasm
Vesicles Tissue enriched Tissue enriched 7 skin: 162.7 breast: 22.3 Cell line enhanced BJ hTERT+: 2.2;PC-3: 5.5;RT4: 2.5 +CHCHD5 C2orf9, MGC11104, MIC14 ENSG00000125611 Coiled-coil-helix-coiled-coil-helix domain containing 5 2 112584240-112589275 Predicted intracellular proteins Evidence at protein level HPA038263 Approved Supported Mitochondria Expressed in all Expressed in all thyroid gland: 33.6 Mixed +PAX8 ENSG00000125618 Paired box 8 2 113215997-113278950 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030062, CAB055097, CAB061888, HPA064554 Enhanced Enhanced Nucleoplasm Endometrial cancer:1.75e-5 (unfavourable) Group enriched Tissue enriched 10 thyroid gland: 644.0 kidney: 65.2 Group enriched 8 EFO-21: 76.3;RPTEC TERT1: 144.9 +INSIG2 ENSG00000125629 Insulin induced gene 2 2 118088452-118110997 Predicted membrane proteins Evidence at protein level CAB033861 Uncertain Pancreatic cancer:2.19e-6 (unfavourable), Renal cancer:4.11e-6 (unfavourable), Head and neck cancer:7.10e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.4 Expressed in all +POLR1B FLJ10816, FLJ21921, RPA2, Rpo1-2 ENSG00000125630 RNA polymerase I subunit B 2 112541915-112577150 Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA037528 Supported Nucleoli
Cytosol Endometrial cancer:2.71e-5 (unfavourable), Pancreatic cancer:5.52e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.0 Expressed in all +CCDC93 FLJ10996 ENSG00000125633 Coiled-coil domain containing 93 2 117915478-118014133 Predicted intracellular proteins Evidence at protein level HPA054183 Approved Supported Vesicles
Plasma membrane Liver cancer:2.97e-6 (unfavourable), Thyroid cancer:9.66e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.9 Expressed in all +PSD4 EFA6B, TIC ENSG00000125637 Pleckstrin and Sec7 domain containing 4 2 113157325-113209396 Predicted intracellular proteins Evidence at protein level HPA034722, HPA034723 Enhanced Liver cancer:9.91e-5 (favourable), Stomach cancer:4.00e-4 (favourable) Expressed in all Mixed parathyroid gland: 34.0 Cell line enhanced HMC-1: 50.4 +SLC25A23 APC2, FLJ30339, MGC2615 ENSG00000125648 Solute carrier family 25 member 23 19 6436079-6465203 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA009675, HPA050883 Approved Supported Mitochondria Renal cancer:1.10e-12 (favourable), Endometrial cancer:1.29e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 141.3 Mixed +PSPN PSP ENSG00000125650 Persephin 19 6375148-6379058 Predicted secreted proteins Evidence at transcript level CAB025366 Approved Expressed in all Mixed cerebral cortex,epididymis,parathyroid gland,thyroid gland: 1.4 Mixed +GTF2F1 BTF4, RAP74, TF2F1, TFIIF ENSG00000125651 General transcription factor IIF subunit 1 19 6379569-6393981 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022793, HPA028707, HPA070752 Supported Enhanced Nucleus
Cell Junctions Endometrial cancer:8.39e-4 (favourable), Renal cancer:9.80e-4 (favourable) Expressed in all Expressed in all ovary: 93.3 Expressed in all +ALKBH7 MGC10974, SPATA11 ENSG00000125652 AlkB homolog 7 19 6372433-6375251 Predicted intracellular proteins Evidence at protein level HPA039571, HPA039872 Approved Renal cancer:7.83e-6 (favourable) Expressed in all Expressed in all testis: 252.4 Expressed in all +CLPP ENSG00000125656 Caseinolytic mitochondrial matrix peptidase proteolytic subunit 19 6361452-6368908 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA010649 Supported Enhanced Mitochondria Pancreatic cancer:6.50e-4 (favourable) Expressed in all Expressed in all appendix: 48.3 Expressed in all +TNFSF9 4-1BB-L ENSG00000125657 Tumor necrosis factor superfamily member 9 19 6530999-6535928 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059857 Approved Golgi apparatus Renal cancer:1.04e-4 (unfavourable) Mixed Mixed cerebral cortex: 3.4 Cell line enhanced HMC-1: 73.8 +GRIA3 GluA3, GLUR3, GLURC, MRX94 ENSG00000125675 Glutamate ionotropic receptor AMPA type subunit 3 X 123184153-123490915 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA058659 Uncertain Tissue enriched Tissue enhanced cerebral cortex: 56.6 adrenal gland: 11.3 Cell line enhanced BJ: 20.3;BJ hTERT+: 28.1;fHDF/TERT166: 35.8;U-2197: 14.1 +THOC2 CXorf3, dJ506G2.1, MRX12, MRX35, THO2 ENSG00000125676 THO complex 2 X 123600561-123733056 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047921 Supported Approved Nucleoplasm Liver cancer:5.77e-5 (unfavourable) Expressed in all Expressed in all epididymis: 46.6 Expressed in all +MED1 CRSP1, CRSP200, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2 ENSG00000125686 Mediator complex subunit 1 17 39404285-39451286 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017696, HPA052818 Approved Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 56.7 Expressed in all +RPL23 L23, rpL17 ENSG00000125691 Ribosomal protein L23 17 38847865-38853843 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003373 Approved Supported Cytosol Renal cancer:4.19e-5 (unfavourable) Expressed in all Expressed in all ovary: 4496.9 Expressed in all +ATG4C APG4C, AUTL1, AUTL3, FLJ14867 ENSG00000125703 Autophagy related 4C cysteine peptidase 1 62784135-62865513 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007049 Approved Approved Nucleoplasm
Cytosol Colorectal cancer:9.83e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 23.5 Expressed in all +CD70 CD27L, CD27LG, TNFSF7 ENSG00000125726 CD70 molecule 19 6583183-6604103 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046582 Uncertain Nucleoplasm Renal cancer:3.22e-4 (unfavourable), Lung cancer:6.29e-4 (unfavourable) Tissue enhanced Tissue enhanced appendix: 4.4 lymph node: 3.8 Cell line enhanced SiHa: 200.2;U-251 MG: 192.3;U-266/70: 304.1;U-266/84: 216.7 +C3 ARMD9, C3a, C3b, CPAMD1 ENSG00000125730 Complement C3 19 6677704-6730562 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003563, CAB004209, HPA020432 Enhanced Renal cancer:1.09e-5 (unfavourable), Liver cancer:8.11e-4 (favourable) Expressed in all Expressed in all liver: 2486.8 Group enriched 6 BJ hTERT+: 287.5;EFO-21: 689.2;Hep G2: 539.6;HSkMC: 386.3;SiHa: 220.2 +SH2D3A NSP1 ENSG00000125731 SH2 domain containing 3A 19 6752160-6767588 Predicted intracellular proteins Evidence at protein level HPA035722, HPA064382 Uncertain Approved Nucleoplasm
Microtubules
Cytokinetic bridge Renal cancer:1.42e-4 (favourable), Prostate cancer:6.21e-4 (unfavourable) Mixed Mixed skin: 14.0 Cell line enhanced A-431: 35.6;HBEC3-KT: 47.1 +TRIP10 CIP4, HSTP, STOT, STP ENSG00000125733 Thyroid hormone receptor interactor 10 19 6737925-6751526 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041934, HPA072625, HPA073886 Approved Supported Nucleoplasm
Vesicles Head and neck cancer:1.76e-4 (favourable), Colorectal cancer:3.61e-4 (unfavourable), Renal cancer:4.66e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 129.0 Mixed +GPR108 LUSTR2 ENSG00000125734 G protein-coupled receptor 108 19 6729914-6737603 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041924, HPA041951, HPA063863 Uncertain Supported Golgi apparatus
Vesicles Renal cancer:1.29e-9 (favourable), Endometrial cancer:1.04e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 75.1 Mixed +TNFSF14 CD258, HVEM-L, LIGHT, LTg ENSG00000125735 Tumor necrosis factor superfamily member 14 19 6661253-6670588 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012700 Approved Renal cancer:6.07e-13 (unfavourable) Tissue enhanced Mixed adipose tissue: 6.8 Cell line enhanced HDLM-2: 22.7;U-937: 10.8 +FOSB AP-1, DKFZp686C0818, G0S3, GOS3, GOSB, MGC42291 ENSG00000125740 FosB proto-oncogene, AP-1 transcription factor subunit 19 45467995-45475179 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB010267, HPA054663 Approved Supported Nucleoplasm
Vesicles Expressed in all Mixed gallbladder: 558.7 Cell line enhanced HMC-1: 11.7;SK-BR-3: 7.4 +OPA3 FLJ22187, MGA3 ENSG00000125741 OPA3, outer mitochondrial membrane lipid metabolism regulator 19 45527427-45602212 Disease related genes, Predicted membrane proteins Evidence at protein level HPA044881 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:9.30e-12 (favourable), Liver cancer:5.60e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 18.0 Expressed in all +SNRPD2 Sm-D2, SNRPD1 ENSG00000125743 Small nuclear ribonucleoprotein D2 polypeptide 19 45687454-45692569 Predicted intracellular proteins Evidence at protein level HPA041437 Supported Uncertain Cytosol Renal cancer:8.58e-5 (unfavourable) Expressed in all Expressed in all ovary: 334.8 Expressed in all +RTN2 NSP2, NSPL1, SPG12 ENSG00000125744 Reticulon 2 19 45485289-45497061 Disease related genes, Predicted membrane proteins Evidence at protein level HPA034941, HPA034948 Approved Approved Nuclear speckles Renal cancer:5.58e-6 (unfavourable) Expressed in all Tissue enriched 6 skeletal muscle: 175.3 placenta: 27.5 Mixed +EML2 ELP70, EMAP-2, EMAP2 ENSG00000125746 Echinoderm microtubule associated protein like 2 19 45606994-45645629 Predicted intracellular proteins Evidence at protein level HPA012757 Approved Approved Vesicles Expressed in all Expressed in all parathyroid gland: 100.7 Mixed +VASP ENSG00000125753 Vasodilator-stimulated phosphoprotein 19 45506579-45526983 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004612, HPA005724 Enhanced Supported Plasma membrane
Cell Junctions
Focal adhesion sites Renal cancer:5.91e-7 (unfavourable), Liver cancer:3.49e-5 (unfavourable) Expressed in all Expressed in all appendix: 90.5 Expressed in all +SYMPK SPK, SYM ENSG00000125755 Symplekin 19 45815410-45863290 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041756, HPA042449 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 74.7 Expressed in all +GPCPD1 GDE5, GDPD6, KIAA1434 ENSG00000125772 Glycerophosphocholine phosphodiesterase 1 20 5544404-5611026 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039556, HPA042987 Uncertain Approved Nucleoplasm Endometrial cancer:1.30e-4 (favourable), Renal cancer:3.73e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 46.5 Mixed +SDCBP2 SITAC18, ST-2 ENSG00000125775 Syndecan binding protein 2 20 1309909-1329239 Predicted intracellular proteins Evidence at protein level HPA054554, HPA064490 Enhanced Approved Vesicles
Cytosol Lung cancer:2.42e-4 (unfavourable), Pancreatic cancer:3.07e-4 (unfavourable), Urothelial cancer:3.37e-4 (favourable) Expressed in all Tissue enhanced duodenum: 135.1;small intestine: 143.9 stomach: 94.5 Cell line enhanced CAPAN-2: 16.0 +PANK2 C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN ENSG00000125779 Pantothenate kinase 2 20 3888839-3929882 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA008440 Approved Supported Cytosol Liver cancer:1.20e-5 (unfavourable) Expressed in all Expressed in all testis: 51.9 Expressed in all +TGM3 TGE ENSG00000125780 Transglutaminase 3 20 2296001-2341078 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004728 Enhanced Tissue enriched Tissue enriched 12 esophagus: 1513.9 tonsil: 126.4 Cell line enriched 7 EFO-21: 5.7 +GNRH2 ENSG00000125787 Gonadotropin releasing hormone 2 20 3043622-3045747 Predicted secreted proteins Evidence at transcript level HPA004338 Uncertain Tissue enhanced Mixed ovary: 2.7 Mixed +DEFB126 bA530N10.1, C20orf8, DEFB-26 ENSG00000125788 Defensin beta 126 20 142369-145751 Disease related genes, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 234 epididymis: 663.6 seminal vesicle: 2.8 Not detected +FOXA2 HNF3B ENSG00000125798 Forkhead box A2 20 22581005-22585455 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB001388, HPA066846 Enhanced Supported Nucleoplasm
Cell Junctions Endometrial cancer:7.57e-6 (favourable), Pancreatic cancer:2.34e-4 (favourable), Ovarian cancer:6.28e-4 (favourable) Mixed Tissue enhanced cervix, uterine: 21.4;lung: 20.5;stomach: 31.0 liver: 11.5 Cell line enhanced A549: 16.1;HBEC3-KT: 14.5;Hep G2: 19.5;PC-3: 24.0;SCLC-21H: 52.3 +CD93 C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4 ENSG00000125810 CD93 molecule 20 23079349-23086340 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA009300, HPA012368 Enhanced Approved Vesicles
Plasma membrane Renal cancer:2.74e-4 (unfavourable) Expressed in all Expressed in all placenta: 197.1 Group enriched 5 HUVEC TERT2: 286.2;TIME: 357.8;U-937: 464.4 +GZF1 dJ322G13.2, ZBTB23, ZNF336 ENSG00000125812 GDNF inducible zinc finger protein 1 20 23362182-23373063 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024520 Uncertain Supported Nucleus
Nucleoli Liver cancer:9.81e-7 (unfavourable) Expressed in all Expressed in all adrenal gland: 25.3 Expressed in all +PAX1 ENSG00000125813 Paired box 1 20 21705659-21718486 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enriched Tissue enriched 11 parathyroid gland: 185.2 tonsil: 17.5 Cell line enriched 6 SCLC-21H: 1.6 +NAPB SNAP-BETA, SNAPB ENSG00000125814 NSF attachment protein beta 20 23374519-23421519 Predicted intracellular proteins Evidence at protein level CAB037225, CAB037227, HPA046149, HPA050196 Approved Uncertain Cytosol Renal cancer:1.14e-4 (unfavourable) Expressed in all Tissue enriched 9 cerebral cortex: 303.2 adrenal gland: 32.1 Expressed in all +CST8 CRES, CTES5 ENSG00000125815 Cystatin 8 20 23491101-23496018 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 208 testis: 20.7 all non-specific tissues: 0.0 Not detected +NKX2-4 NKX2.4, NKX2D ENSG00000125816 NK2 homeobox 4 20 21395367-21398028 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA074996 Approved Nuclear bodies Not detected Tissue enriched 20 testis: 2.0 all non-specific tissues: 0.0 Cell line enhanced HAP1: 1.9;HEK 293: 3.6;SCLC-21H: 3.0;SK-MEL-30: 2.3 +CENPB ENSG00000125817 Centromere protein B 20 3783851-3786690 Predicted intracellular proteins Evidence at protein level CAB011626, HPA053507, HPA054405 Approved Enhanced Nuclear bodies Liver cancer:6.09e-4 (unfavourable) Expressed in all Expressed in all skin: 43.4 Expressed in all +PSMF1 PI31 ENSG00000125818 Proteasome inhibitor subunit 1 20 1113263-1189415 Predicted intracellular proteins Evidence at protein level HPA041122, HPA041300 Approved Enhanced Cytosol Expressed in all Expressed in all testis: 136.0 Expressed in all +NKX2-2 NKX2.2, NKX2B ENSG00000125820 NK2 homeobox 2 20 21511010-21514026 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003468 Approved Group enriched Tissue enhanced cerebral cortex: 9.9;stomach: 2.6 duodenum: 2.4 Cell line enhanced HAP1: 4.3;T-47d: 4.6;U-138 MG: 17.1;U-2 OS: 3.7;WM-115: 7.0 +DTD1 bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, MGC119131, MGC41905, pqn-68 ENSG00000125821 D-tyrosyl-tRNA deacylase 1 20 18567453-18763917 Predicted intracellular proteins Evidence at protein level HPA040981, HPA042653 Uncertain Uncertain Nucleoli
Cytosol Expressed in all Expressed in all cerebral cortex: 55.8 Mixed +CSTL1 CTES1, dJ322G13.4 ENSG00000125823 Cystatin like 1 20 23439685-23444930 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 37 testis: 4.6 placenta,seminal vesicle,skin,small intestine,stomach: 0.1 Not detected +RBCK1 C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4 ENSG00000125826 RANBP2-type and C3HC4-type zinc finger containing 1 20 407498-430966 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Renal cancer:7.41e-9 (unfavourable) Expressed in all Expressed in all spleen: 51.2 Expressed in all +TMX4 DJ971N18.2, KIAA1162, PDIA14, TXNDC13 ENSG00000125827 Thioredoxin related transmembrane protein 4 20 7977348-8019829 Predicted membrane proteins Evidence at protein level HPA000399, HPA015752 Enhanced Supported Nuclear membrane Renal cancer:2.60e-5 (favourable) Expressed in all Expressed in all testis: 118.2 Expressed in all +CST11 CST8L, CTES2, dJ322G13.6 ENSG00000125831 Cystatin 11 20 23450403-23452857 Predicted secreted proteins Evidence at protein level HPA053399 Enhanced Not detected Tissue enriched 299 epididymis: 266.6 testis: 0.8 Not detected +STK35 bA550O8.2, CLIK1 ENSG00000125834 Serine/threonine kinase 35 20 2101611-2177038 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026452, HPA051673 Uncertain Supported Nucleus
Nuclear bodies Liver cancer:9.46e-6 (unfavourable) Expressed in all Expressed in all testis: 25.2 Expressed in all +SNRPB COD, Sm-B/B', SmB/SmB', snRNP-B, SNRPB1 ENSG00000125835 Small nuclear ribonucleoprotein polypeptides B and B1 20 2461634-2470853 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003482, CAB009610, HPA067842 Approved Supported Nucleoplasm Liver cancer:1.07e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 202.0 Expressed in all +NRSN2 C20orf98, dJ1103G7.6 ENSG00000125841 Neurensin 2 20 346782-359660 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA015967 Approved Approved Nucleoplasm
Vesicles
Cytosol Pancreatic cancer:1.61e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 126.1 parathyroid gland: 69.0 Mixed +AP5S1 C20orf29, FLJ11168 ENSG00000125843 Adaptor related protein complex 5 sigma 1 subunit 20 3820524-3828837 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB034200, HPA043533, HPA048244 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:5.53e-5 (favourable) Expressed in all Expressed in all testis: 12.4 Expressed in all +RRBP1 ES/130, hES ENSG00000125844 Ribosome binding protein 1 20 17613678-17682295 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009026, HPA011924 Enhanced Enhanced Endoplasmic reticulum Endometrial cancer:1.41e-4 (favourable), Urothelial cancer:9.38e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 218.2 Expressed in all +BMP2 BMP2A ENSG00000125845 Bone morphogenetic protein 2 20 6767664-6780280 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA058610, CAB078457 Enhanced Vesicles Expressed in all Mixed thyroid gland: 31.2 Cell line enhanced CACO-2: 25.6;HeLa: 13.4;hTERT-HME1: 13.5;RT4: 19.5 +ZNF133 pHZ-13, pHZ-66, ZNF150 ENSG00000125846 Zinc finger protein 133 20 18288283-18316996 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001493 Enhanced Approved Nucleus
Vesicles Liver cancer:4.46e-6 (unfavourable), Renal cancer:2.20e-5 (unfavourable) Expressed in all Expressed in all epididymis: 20.1 Mixed +FLRT3 ENSG00000125848 Fibronectin leucine rich transmembrane protein 3 20 14322988-14337616 Disease related genes, Predicted membrane proteins Evidence at protein level CAB026166, HPA056033 Enhanced Supported Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.49e-7 (favourable), Lung cancer:9.85e-5 (unfavourable), Pancreatic cancer:1.54e-4 (unfavourable) Expressed in all Mixed lung: 32.3 Cell line enhanced AF22: 32.9;hTCEpi: 45.3;WM-115: 75.5 +OVOL2 bA504H3.3, CHED, CHED1, HOVO2, ZNF339 ENSG00000125850 Ovo like zinc finger 2 20 17956979-18059188 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038531 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced stomach: 8.0 colon: 3.5 Cell line enhanced A-431: 5.2;CAPAN-2: 6.7;HaCaT: 5.0;SCLC-21H: 10.2;SK-BR-3: 4.4 +PCSK2 NEC2, PC2, SPC2 ENSG00000125851 Proprotein convertase subtilisin/kexin type 2 20 17226107-17484578 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049627 Enhanced Approved Vesicles Group enriched Tissue enhanced adrenal gland: 37.5;cerebral cortex: 31.7 skin: 16.5 Group enriched 6 AF22: 59.2;SCLC-21H: 18.5 +GFRA4 ENSG00000125861 GDNF family receptor alpha 4 20 3659292-3663399 Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced thyroid gland: 1.4 testis: 0.3 Not detected +MKKS BBS6 ENSG00000125863 McKusick-Kaufman syndrome 20 10401009-10434222 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041071, HPA044233 Enhanced Supported Centrosome Renal cancer:3.79e-9 (favourable), Liver cancer:9.84e-5 (unfavourable) Expressed in all Expressed in all testis: 70.6 Expressed in all +BFSP1 CP115, CP94, filensin, LIFL-H ENSG00000125864 Beaded filament structural protein 1 20 17493905-17569220 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040748, HPA042038 Enhanced Supported Plasma membrane
Cytosol Endometrial cancer:1.39e-4 (favourable) Mixed Mixed testis: 6.5 Cell line enhanced RPTEC TERT1: 14.8 +DSTN ACTDP, ADF ENSG00000125868 Destrin, actin depolymerizing factor 20 17569863-17609919 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037094 Approved Expressed in all Expressed in all seminal vesicle: 1055.1 Expressed in all +LAMP5 BAD-LAMP, C20orf103, dJ1119D9.3, UNC-46 ENSG00000125869 Lysosomal associated membrane protein family member 5 20 9514358-9530524 Predicted membrane proteins Evidence at protein level HPA004802, HPA070765 Uncertain Approved Mitotic spindle
Microtubule organizing center
Cytosol Renal cancer:6.46e-6 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 44.9;ovary: 24.6 fallopian tube: 14.9 Group enriched 9 Karpas-707: 298.2;SH-SY5Y: 80.2;THP-1: 100.4 +SNRPB2 Msl1, U2B'' ENSG00000125870 Small nuclear ribonucleoprotein polypeptide B2 20 16729961-16742563 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050814, HPA076104 Supported Supported Nuclear speckles Liver cancer:6.03e-7 (unfavourable), Renal cancer:2.79e-4 (unfavourable), Endometrial cancer:7.57e-4 (unfavourable) Expressed in all Expressed in all lymph node: 49.8 Expressed in all +MGME1 bA504H3.4, C20orf72, DDK1 ENSG00000125871 Mitochondrial genome maintenance exonuclease 1 20 17968913-17991122 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040913 Approved Supported Mitochondria Liver cancer:6.98e-8 (unfavourable), Renal cancer:1.13e-7 (unfavourable) Expressed in all Expressed in all skin: 39.7 Expressed in all +LRRN4 C20orf75, dJ1056H1.1, NLRR4 ENSG00000125872 Leucine rich repeat neuronal 4 20 6040778-6054049 Predicted membrane proteins Evidence at protein level HPA075974 Approved Nucleoli
Cytosol Group enriched Tissue enriched 10 lung: 13.5 fallopian tube: 1.2 Cell line enriched 12 RPTEC TERT1: 53.0 +TBC1D20 C20orf140, dJ852M4.2 ENSG00000125875 TBC1 domain family member 20 20 435480-462553 Disease related genes, Predicted membrane proteins Evidence at protein level HPA043613 Approved Expressed in all Expressed in all parathyroid gland: 31.2 Expressed in all +ITPA C20orf37, dJ794I6.3, HLC14-06-P ENSG00000125877 Inosine triphosphatase 20 3208868-3223870 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA022824 Approved Supported Cytosol Liver cancer:2.54e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 40.3 Expressed in all +TCF15 bHLHa40, EC2, PARAXIS ENSG00000125878 Transcription factor 15 (basic helix-loop-helix) 20 603797-610398 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050998, HPA060221 Uncertain Supported Nuclear speckles Ovarian cancer:3.25e-4 (unfavourable) Mixed Group enriched 5 adipose tissue: 6.3;heart muscle: 3.4;placenta: 4.8;skeletal muscle: 4.6;testis: 1.3 lung: 0.7 Cell line enhanced HEL: 9.5;HMC-1: 14.7 +OTOR FDP, MIAL, MIAL1 ENSG00000125879 Otoraplin 20 16748358-16770062 Predicted secreted proteins Evidence at protein level HPA024335 Uncertain Not detected Not detected all non-specific tissues: 0.0 Group enriched 50 SH-SY5Y: 2.8;SK-BR-3: 9.6;T-47d: 2.3 +MCM8 C20orf154, dJ967N21.5, MGC119522, MGC119523, MGC12866, MGC4816, REC ENSG00000125885 Minichromosome maintenance 8 homologous recombination repair factor 20 5950652-5998977 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA045141 Supported Nucleoplasm Liver cancer:9.30e-8 (unfavourable), Pancreatic cancer:7.50e-4 (unfavourable) Expressed in all Tissue enhanced testis: 27.6 lymph node: 10.2 Expressed in all +BANF2 BAF-L, BAF2, BAFL, C20orf179, dJ803K15.1 ENSG00000125888 Barrier to autointegration factor 2 20 17693672-17735871 Predicted intracellular proteins Evidence at protein level HPA042635 Approved Not detected Tissue enriched 29 testis: 125.1 pancreas: 4.3 Cell line enhanced CACO-2: 1.5 +TMEM74B C20orf46, FLJ11190 ENSG00000125895 Transmembrane protein 74B 20 1180561-1185415 Predicted membrane proteins Evidence at transcript level HPA045213 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:2.55e-7 (unfavourable), Pancreatic cancer:3.07e-5 (favourable) Mixed Mixed small intestine: 27.0 Cell line enhanced CACO-2: 6.6;Hep G2: 6.9;K-562: 15.6 +FAM110A bA371L19.3, C20orf55 ENSG00000125898 Family with sequence similarity 110 member A 20 833715-857463 Predicted intracellular proteins Evidence at protein level CAB034110, HPA069240 Uncertain Supported Nucleus
Vesicles
Cytosol Renal cancer:4.42e-4 (unfavourable) Expressed in all Tissue enhanced skin: 31.3 spleen: 21.3 Cell line enhanced SK-BR-3: 62.8 +SIRPD dJ576H24.4, PTPNS1L2 ENSG00000125900 Signal regulatory protein delta 20 1534251-1558843 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042663 Enhanced Not detected Tissue enriched 18 testis: 72.6 appendix: 3.9 Cell line enhanced HL-60: 1.1;HMC-1: 1.5;NB-4: 1.5;THP-1: 3.5 +MRPS26 C20orf193, dJ534B8.3, MRP-S13, MRP-S26, RPMS13 ENSG00000125901 Mitochondrial ribosomal protein S26 20 3045945-3048254 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA045472, HPA054610 Supported Enhanced Mitochondria Expressed in all Expressed in all prostate: 50.0 Expressed in all +DEFB129 bA530N10.3, C20orf87, DEFB-29 ENSG00000125903 Defensin beta 129 20 227258-229886 Predicted secreted proteins Evidence at protein level HPA014581 Supported Not detected Tissue enriched 494 epididymis: 2368.3 seminal vesicle: 4.7 Cell line enhanced NB-4: 1.7;SH-SY5Y: 1.3 +S1PR4 EDG6 ENSG00000125910 Sphingosine-1-phosphate receptor 4 19 3172346-3180332 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA060601, HPA067232 Uncertain Mitochondria Head and neck cancer:1.45e-6 (favourable), Cervical cancer:1.33e-4 (favourable), Endometrial cancer:2.22e-4 (favourable), Renal cancer:2.87e-4 (unfavourable), Breast cancer:3.13e-4 (favourable) Expressed in all Tissue enhanced lymph node: 18.1;spleen: 26.4 appendix: 14.0 Cell line enhanced HDLM-2: 22.2;HL-60: 25.5;NB-4: 19.9;REH: 81.1;U-937: 23.6 +NCLN NET59, NICALIN ENSG00000125912 Nicalin 19 3185563-3209575 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006625 Approved Uncertain Nucleoplasm
Lipid droplets Renal cancer:8.37e-5 (unfavourable), Stomach cancer:8.82e-5 (favourable), Endometrial cancer:1.19e-4 (favourable), Liver cancer:2.15e-4 (unfavourable) Expressed in all Expressed in all duodenum: 33.9 Expressed in all +CITED1 MSG1 ENSG00000125931 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 X 72301638-72307187 Predicted intracellular proteins Evidence at protein level HPA049051 Enhanced Supported Nucleoplasm
Cytosol Thyroid cancer:3.95e-4 (favourable), Testis cancer:6.10e-4 (favourable) Tissue enriched Tissue enriched 7 epididymis: 1798.6 testis: 258.7 Cell line enhanced AN3-CA: 52.8;SCLC-21H: 30.2;SK-MEL-30: 179.8 +HNRNPR hnRNP-R, HNRPR ENSG00000125944 Heterogeneous nuclear ribonucleoprotein R 1 23303771-23344336 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011687, HPA026092 Enhanced Enhanced Nucleoplasm Liver cancer:1.32e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 66.5 Expressed in all +ZNF436 KIAA1710, Zfp46 ENSG00000125945 Zinc finger protein 436 1 23359448-23369442 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043817 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Mixed ovary: 12.4 Cell line enhanced HSkMC: 26.4 +MAX bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8 ENSG00000125952 MYC associated factor X 14 65006174-65102695 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000328, HPA003474 Enhanced Supported Nucleoplasm
Golgi apparatus
Vesicles Thyroid cancer:2.12e-4 (favourable), Renal cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 78.8 Expressed in all +CHURC1-FNTB ENSG00000125954 CHURC1-FNTB readthrough 14 64914485-65061803 Predicted intracellular proteins Evidence at protein level CAB009260 Uncertain Not detected Mixed adipose tissue: 1.5 Mixed +ARMCX5 FLJ12969, GASP5 ENSG00000125962 Armadillo repeat containing, X-linked 5 X 102599168-102604159 Predicted intracellular proteins Evidence at protein level HPA000996 Approved Approved Nuclear speckles
Cytosol Lung cancer:6.58e-5 (favourable) Expressed in all Expressed in all prostate: 33.5 Cell line enhanced RH-30: 86.0 +GDF5 BMP14, CDMP1 ENSG00000125965 Growth differentiation factor 5 20 35433347-35454746 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA015648 Uncertain Tissue enriched Tissue enhanced salivary gland: 4.1 seminal vesicle: 1.7 Cell line enhanced ASC TERT1: 12.2;BJ hTERT+: 4.4;HHSteC: 4.8;HSkMC: 10.3;U-87 MG: 6.5 +MMP24 MT5-MMP ENSG00000125966 Matrix metallopeptidase 24 20 35226654-35277000 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at transcript level HPA049280 Approved Nucleoli
Plasma membrane Renal cancer:8.17e-11 (favourable) Mixed Tissue enhanced cerebral cortex: 10.6 lung: 7.0 Cell line enhanced A549: 32.8;CACO-2: 46.1;RPTEC TERT1: 18.5;U-2 OS: 18.9 +NECAB3 APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, NIP1, SYTIP2, XB51 ENSG00000125967 N-terminal EF-hand calcium binding protein 3 20 33657087-33674463 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044785, HPA070595, HPA071786 Supported Supported Golgi apparatus Pancreatic cancer:3.19e-5 (favourable), Renal cancer:7.81e-4 (unfavourable), Endometrial cancer:9.57e-4 (unfavourable) Expressed in all Mixed prostate: 34.6 Expressed in all +ID1 bHLHb24, dJ857M17.1.2 ENSG00000125968 Inhibitor of DNA binding 1, HLH protein 20 31605283-31606515 Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transcription factors Evidence at protein level CAB025915, HPA051456, HPA058518 Approved Enhanced Nucleoplasm
Golgi apparatus Lung cancer:4.85e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 213.9 Cell line enhanced EFO-21: 475.3;PC-3: 474.7 +RALY HNRPCL2, P542 ENSG00000125970 RALY heterogeneous nuclear ribonucleoprotein 20 33993646-34108308 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040971, HPA043614 Enhanced Enhanced Nucleoplasm Liver cancer:3.60e-4 (unfavourable) Expressed in all Expressed in all testis: 140.8 Expressed in all +DYNLRB1 DNCL2A, DNLC2A, ROBLD1 ENSG00000125971 Dynein light chain roadblock-type 1 20 34516409-34540958 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009845 Approved Liver cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 341.0 Expressed in all +C20orf173 dJ477O4.4 ENSG00000125975 Chromosome 20 open reading frame 173 20 35523186-35529652 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 137 testis: 34.3 skin: 0.2 Not detected +EIF2S2 EIF2, EIF2beta, PPP1R67 ENSG00000125977 Eukaryotic translation initiation factor 2 subunit beta 20 34088298-34112332 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034415, HPA041262, HPA041332 Approved Supported Nucleoli
Endoplasmic reticulum Renal cancer:9.64e-10 (unfavourable), Liver cancer:3.23e-5 (unfavourable), Endometrial cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all placenta: 74.3 Expressed in all +ERGIC3 C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84 ENSG00000125991 ERGIC and golgi 3 20 35542021-35557634 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015242, HPA015968 Approved Supported Nucleoplasm Liver cancer:2.20e-7 (unfavourable), Renal cancer:9.81e-5 (unfavourable) Expressed in all Expressed in all epididymis: 530.3 Expressed in all +ROMO1 bA353C18.2, C20orf52, MTGMP ENSG00000125995 Reactive oxygen species modulator 1 20 35699272-35700984 Predicted intracellular proteins, Transporters Evidence at protein level HPA012782 Uncertain Expressed in all Expressed in all adrenal gland: 120.8 Expressed in all +FAM83C C20orf128, dJ614O4.7 ENSG00000125998 Family with sequence similarity 83 member C 20 35285731-35292401 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034227, HPA049978 Uncertain Tissue enhanced Group enriched 17 esophagus: 19.8;skin: 43.0 tonsil: 1.8 Not detected +BPIFB1 bA49G10.6, C20orf114, dJ1187J4.1, LPLUNC1, MGC14597, VEMSGP ENSG00000125999 BPI fold containing family B member 1 20 33273480-33309878 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA024256 Supported Tissue enhanced Tissue enhanced cervix, uterine: 839.4;stomach: 443.3 lung: 157.3 Cell line enhanced CAPAN-2: 2.2;RT4: 1.6;SK-BR-3: 3.1 +CEP250 C-NAP1, CEP2 ENSG00000126001 Centrosomal protein 250 20 35455164-35519280 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064875 Supported Centrosome Liver cancer:1.77e-7 (unfavourable), Renal cancer:1.97e-6 (unfavourable), Pancreatic cancer:9.27e-6 (favourable) Expressed in all Expressed in all testis: 35.1 Expressed in all +PLAGL2 ZNF900 ENSG00000126003 PLAG1 like zinc finger 2 20 32192503-32207791 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005900 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 25.8 Expressed in all +MMP24-AS1 ENSG00000126005 MMP24 antisense RNA 1 20 35201745-35278131 Predicted intracellular proteins Evidence at transcript level Expressed in all Expressed in all adipose tissue: 46.9 Expressed in all +GRPR BB2, BB2R ENSG00000126010 Gastrin releasing peptide receptor X 16123556-16153021 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA069604 Enhanced Plasma membrane Tissue enhanced Tissue enhanced pancreas: 4.2 breast,epididymis: 2.6 Group enriched 10 PC-3: 30.0;T-47d: 37.9;U-138 MG: 53.4 +KDM5C DXS1272E, JARID1C, MRX13, SMCX, XE169 ENSG00000126012 Lysine demethylase 5C X 53191321-53225422 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038244, HPA046147 Enhanced Nucleoplasm
Cytosol Liver cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 66.7 Expressed in all +AMOT KIAA1071 ENSG00000126016 Angiomotin X 112774503-112840815 Predicted intracellular proteins Evidence at protein level HPA067290, HPA067853 Enhanced Supported Nucleus
Cell Junctions Renal cancer:4.21e-9 (favourable), Lung cancer:3.94e-4 (favourable) Expressed in all Tissue enhanced epididymis: 177.9 seminal vesicle: 38.6 Cell line enhanced AF22: 24.7;HAP1: 28.1 +TMEM115 PL6 ENSG00000126062 Transmembrane protein 115 3 50354749-50359610 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB006319, HPA015497 Supported Supported Golgi apparatus Renal cancer:1.04e-7 (favourable), Liver cancer:3.73e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 37.3 Expressed in all +PSMB2 HC7-I ENSG00000126067 Proteasome subunit beta 2 1 35599544-35641844 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026322, HPA026324 Approved Enhanced Nucleoplasm Liver cancer:3.49e-7 (unfavourable), Renal cancer:2.80e-6 (unfavourable) Expressed in all Expressed in all placenta: 43.3 Expressed in all +AGO3 EIF2C3, FLJ12765, hAGO3 ENSG00000126070 Argonaute 3, RISC catalytic component 1 35930718-36072500 Predicted intracellular proteins Evidence at protein level HPA048342, HPA075436 Uncertain Supported Nucleoplasm
Cytoplasmic bodies Endometrial cancer:5.70e-4 (unfavourable) Mixed Mixed testis: 10.3 Expressed in all +UROD ENSG00000126088 Uroporphyrinogen decarboxylase 1 45012147-45015575 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027468, HPA028668, HPA030350 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:2.48e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 115.4 Expressed in all +ST3GAL3 MRT12, SIAT6 ENSG00000126091 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 1 43705824-43931165 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051102 Uncertain Expressed in all Expressed in all skeletal muscle: 30.5 Mixed +TMEM53 FLJ22353, NET4 ENSG00000126106 Transmembrane protein 53 1 44635238-44674555 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021134 Approved Approved Golgi apparatus
Focal adhesion sites Renal cancer:1.02e-5 (favourable), Ovarian cancer:6.96e-4 (favourable) Expressed in all Mixed testis: 23.3 Expressed in all +HECTD3 FLJ21156 ENSG00000126107 HECT domain E3 ubiquitin protein ligase 3 1 45002540-45011329 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027467 Approved Thyroid cancer:1.85e-6 (favourable), Liver cancer:2.14e-5 (unfavourable) Expressed in all Expressed in all duodenum,parathyroid gland: 47.3 Expressed in all +KLC1 hKLC1B, hKLC1G, hKLC1J, hKLC1N, hKLC1P, hKLC1R, hKLC1S, KLC, KNS2, KNS2A ENSG00000126214 Kinesin light chain 1 14 103561896-103714249 Predicted intracellular proteins Evidence at protein level CAB009798, HPA044617, HPA052450 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:6.75e-4 (favourable), Renal cancer:7.17e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 467.9 Expressed in all +XRCC3 ENSG00000126215 X-ray repair cross complementing 3 14 103697609-103715504 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA062422, HPA068953 Enhanced Nucleus Expressed in all Expressed in all skin: 46.0 Expressed in all +TUBGCP3 GCP3, SPBC98, Spc98p ENSG00000126216 Tubulin gamma complex associated protein 3 13 112485005-112588167 Predicted intracellular proteins Evidence at protein level HPA043913 Approved Expressed in all Expressed in all testis: 33.2 Expressed in all +MCF2L ARHGEF14, DBS, KIAA0362, OST ENSG00000126217 MCF.2 cell line derived transforming sequence like 13 112894378-113099739 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:9.14e-6 (favourable), Urothelial cancer:2.63e-5 (favourable), Pancreatic cancer:4.36e-5 (favourable), Endometrial cancer:6.01e-4 (favourable) Expressed in all Mixed cerebral cortex: 62.4 Cell line enhanced SCLC-21H: 77.5;SK-BR-3: 33.1;WM-115: 59.3 +F10 ENSG00000126218 Coagulation factor X 13 113122814-113149529 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Pancreatic cancer:1.82e-5 (favourable), Renal cancer:5.14e-5 (unfavourable) Tissue enriched Tissue enhanced liver: 67.5 cervix, uterine: 51.6 Cell line enhanced BJ: 12.5;Hep G2: 40.8;SH-SY5Y: 30.0 +PCID2 FLJ11305 ENSG00000126226 PCI domain containing 2 13 113177539-113208715 Predicted intracellular proteins Evidence at protein level HPA069107, HPA073074 Uncertain Approved Nucleus
Nucleoli Renal cancer:4.24e-6 (unfavourable), Head and neck cancer:7.80e-5 (unfavourable) Expressed in all Expressed in all testis: 81.9 Expressed in all +PROZ PZ ENSG00000126231 Protein Z, vitamin K dependent plasma glycoprotein 13 113158654-113172383 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA052006 Enhanced Liver cancer:3.46e-4 (favourable) Tissue enriched Group enriched 14 kidney: 14.5;liver: 27.4 testis: 1.5 Cell line enhanced HaCaT: 1.9;Hep G2: 2.4 +SLURP1 ANUP, ARS, ArsB, LY6LS, MDM ENSG00000126233 Secreted LY6/PLAUR domain containing 1 8 142740944-142742411 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA050967 Approved Tissue enhanced Group enriched 33 esophagus: 740.6;skin: 297.1 tonsil: 15.7 Cell line enhanced HaCaT: 1.1;MCF7: 1.1;T-47d: 2.4 +LRFN3 FIGLER1, MGC2656, SALM4 ENSG00000126243 Leucine rich repeat and fibronectin type III domain containing 3 19 35935358-35945767 Predicted membrane proteins Evidence at transcript level HPA048923 Approved Renal cancer:8.46e-7 (favourable) Expressed in all Mixed cerebral cortex: 8.2 Mixed +IGFLR1 FLJ22573, TMEM149, U2AF1L4 ENSG00000126246 IGF like family receptor 1 19 35738801-35742453 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012369 Uncertain Approved Focal adhesion sites Ovarian cancer:1.59e-5 (favourable), Cervical cancer:6.55e-4 (favourable) Expressed in all Mixed lymph node: 37.8 Cell line enhanced HMC-1: 29.7;U-266/70: 26.0 +CAPNS1 30K, CANP, CANPS, CAPN4, CDPS ENSG00000126247 Calpain small subunit 1 19 36139575-36150353 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006872 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all esophagus: 515.2 Expressed in all +PDCD2L MGC13096 ENSG00000126249 Programmed cell death 2 like 19 34404384-34426168 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA052181 Approved Uncertain Mitochondria Renal cancer:1.23e-5 (unfavourable), Liver cancer:5.81e-4 (unfavourable) Expressed in all Mixed testis: 17.5 Mixed +GPR42 FFAR3L, GPR41L, GPR42P ENSG00000126251 G protein-coupled receptor 42 (gene/pseudogene) 19 35370929-35372962 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA044681 Uncertain Not detected Not detected appendix,small intestine: 0.3 Not detected +RBM42 MGC10433 ENSG00000126254 RNA binding motif protein 42 19 35629030-35637686 Predicted intracellular proteins Evidence at protein level HPA043671 Supported Approved Nucleus
Cytosol Expressed in all Expressed in all spleen: 38.7 Expressed in all +KIRREL2 DKFZp564A1164, FILTRIN, MGC15718, NEPH3, NLG1 ENSG00000126259 Kin of IRRE like 2 (Drosophila) 19 35855861-35867109 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA071587, HPA074326 Supported Microtubule organizing center Mixed Tissue enriched 8 pancreas: 11.6 cerebral cortex: 1.4 Cell line enhanced HDLM-2: 20.2;HMC-1: 29.3 +UBA2 ARX, FLJ13058, HRIHFB2115, SAE2 ENSG00000126261 Ubiquitin like modifier activating enzyme 2 19 34428352-34471251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041436 Supported Supported Nucleoplasm Liver cancer:3.76e-4 (unfavourable), Renal cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all testis: 168.1 Expressed in all +FFAR2 FFA2R, GPR43 ENSG00000126262 Free fatty acid receptor 2 19 35443907-35451767 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA023985 Approved Tissue enhanced Tissue enhanced appendix: 25.5;bone marrow: 13.3 spleen: 10.8 Cell line enhanced HMC-1: 3.5;U-937: 1.3 +HCST DAP10, DKFZP586C1522, KAP10, PIK3AP ENSG00000126264 Hematopoietic cell signal transducer 19 35902480-35904377 Predicted membrane proteins Evidence at protein level CAB034435, HPA063026 Enhanced Uncertain Vesicles Renal cancer:1.59e-10 (unfavourable), Melanoma:6.70e-4 (favourable) Expressed in all Expressed in all bone marrow: 154.3 Cell line enhanced HEL: 207.8;HL-60: 107.2;HMC-1: 130.2;THP-1: 117.5;U-937: 204.7 +FFAR1 FFA1R, GPR40 ENSG00000126266 Free fatty acid receptor 1 19 35351552-35353862 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enhanced bone marrow: 1.9 ovary: 1.2 Cell line enhanced U-698: 1.1 +COX6B1 COX6B, COXG ENSG00000126267 Cytochrome c oxidase subunit 6B1 19 35648223-35658861 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004192 Enhanced Supported Mitochondria Renal cancer:5.42e-4 (favourable) Expressed in all Expressed in all heart muscle: 462.5 Expressed in all +KRT36 KRTHA6 ENSG00000126337 Keratin 36 17 41486136-41492546 Plasma proteins, Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enhanced skin: 2.1;tonsil: 1.5 cervix, uterine,spleen: 0.5 Cell line enriched 11 Karpas-707: 2.2 +THRA AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3 ENSG00000126351 Thyroid hormone receptor, alpha 17 40058290-40093867 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009654, CAB023349 Uncertain Supported Cytosol Renal cancer:6.05e-8 (favourable), Lung cancer:1.84e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 238.9 Expressed in all +CCR7 BLR2, CD197, CDw197, CMKBR7, EBI1 ENSG00000126353 C-C motif chemokine receptor 7 17 40553769-40565472 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB003796, HPA031383, HPA074467 Enhanced Supported Mitochondria Head and neck cancer:7.61e-7 (favourable), Cervical cancer:8.03e-6 (favourable), Breast cancer:3.84e-4 (favourable), Testis cancer:7.72e-4 (unfavourable) Mixed Group enriched 6 appendix: 88.8;lymph node: 97.1;spleen: 39.3;tonsil: 77.2 urinary bladder: 12.4 Cell line enriched 79 HDLM-2: 1284.5 +NR1D1 ear-1, hRev, Rev-ErbAalpha, THRA1, THRAL ENSG00000126368 Nuclear receptor subfamily 1 group D member 1 17 40092787-40100725 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007935 Uncertain Supported Nuclear bodies Melanoma:1.36e-4 (favourable), Colorectal cancer:1.94e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 37.4 Expressed in all +FRMD8 FKSG44, FLJ90369 ENSG00000126391 FERM domain containing 8 11 65386599-65413525 Predicted intracellular proteins Evidence at protein level HPA002861, HPA005506 Approved Approved Nucleus
Nucleoli
Cytosol Liver cancer:9.94e-5 (unfavourable) Expressed in all Expressed in all skin: 24.9 Expressed in all +PRDX5 ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10 ENSG00000126432 Peroxiredoxin 5 11 64318088-64321811 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008661, HPA037915, HPA037916 Enhanced Enhanced Mitochondria
Cytosol Renal cancer:1.24e-5 (favourable) Expressed in all Expressed in all fallopian tube: 606.1 Expressed in all +BCL2L12 ENSG00000126453 BCL2 like 12 19 49665142-49673916 Predicted intracellular proteins Evidence at protein level HPA020856 Approved Approved Cytosol Renal cancer:8.75e-5 (unfavourable) Expressed in all Expressed in all lymph node: 24.6 Expressed in all +IRF3 ENSG00000126456 Interferon regulatory factor 3 19 49659569-49665875 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004895, CAB013018 Approved Supported Cytosol Renal cancer:1.56e-7 (unfavourable), Urothelial cancer:3.61e-4 (favourable) Expressed in all Expressed in all lymph node: 47.2 Expressed in all +PRMT1 ANM1, HCP1, HRMT1L2 ENSG00000126457 Protein arginine methyltransferase 1 19 49675786-49689029 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022550, HPA069769, HPA072136 Enhanced Supported Nucleoplasm Liver cancer:8.04e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 181.1 Expressed in all +RRAS ENSG00000126458 Related RAS viral (r-ras) oncogene homolog 19 49635292-49640201 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010160, HPA060364, CAB069439 Uncertain Approved Vesicles Renal cancer:1.54e-9 (unfavourable), Glioma:6.03e-5 (unfavourable), Lung cancer:5.28e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 209.2 Mixed +PRRG2 PRGP2 ENSG00000126460 Proline rich and Gla domain 2 19 49580646-49591015 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010702 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:3.82e-9 (favourable) Expressed in all Mixed parathyroid gland: 29.5 Cell line enhanced CAPAN-2: 13.1;T-47d: 13.6;U-266/84: 12.9 +SCAF1 FLJ00034, SR-A1 ENSG00000126461 SR-related CTD associated factor 1 19 49642125-49658642 Predicted intracellular proteins Evidence at protein level HPA046828, HPA054593 Approved Approved Nucleoplasm
Cytosol Colorectal cancer:9.59e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 51.6 Expressed in all +PRR12 KIAA1205 ENSG00000126464 Proline rich 12 19 49591643-49626439 Predicted intracellular proteins Evidence at protein level HPA011959 Approved Approved Cytosol Expressed in all Mixed skin: 15.3 Expressed in all +TSKS PPP1R161, TSSKS ENSG00000126467 Testis specific serine kinase substrate 19 49739753-49763330 Predicted intracellular proteins Evidence at protein level HPA045729 Enhanced Tissue enhanced Tissue enriched 43 testis: 72.4 skin: 1.6 Cell line enhanced K-562: 1.7;NB-4: 7.2;THP-1: 1.6 +FLRT1 MGC21624, SPG68 ENSG00000126500 Fibronectin leucine rich transmembrane protein 1 11 64103188-64119173 Predicted membrane proteins Evidence at protein level HPA054589 Uncertain Mixed Tissue enhanced adrenal gland: 5.9;cerebral cortex: 12.5 cervix, uterine: 4.0 Cell line enhanced SCLC-21H: 6.4;SH-SY5Y: 14.3;THP-1: 7.6 +ASL ENSG00000126522 Argininosuccinate lyase 7 66075798-66093558 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003696, HPA016646 Supported Approved Cytosol Cervical cancer:4.05e-6 (unfavourable) Expressed in all Expressed in all liver: 97.5 Expressed in all +SBDS CGI-97, FLJ10917, SDS, SWDS ENSG00000126524 SBDS ribosome assembly guanine nucleotide exchange factor 7 66987677-66995601 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028891 Approved Supported Nucleus
Cytosol Breast cancer:1.49e-4 (unfavourable), Head and neck cancer:3.65e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 243.3 Expressed in all +CSN1S1 CASA, CSN1 ENSG00000126545 Casein alpha s1 4 69931081-69946574 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035659, HPA057031 Enhanced Tissue enriched Tissue enriched 85 breast: 1600.9 adipose tissue: 18.9 Not detected +STATH STR ENSG00000126549 Statherin 4 69995930-70002570 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA044569 Enhanced Group enriched Tissue enriched 1719 salivary gland: 44726.6 ovary: 26.0 Not detected +HTN1 HIS1 ENSG00000126550 Histatin 1 4 70050402-70058845 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 1777 salivary gland: 24297.5 ovary: 13.6 Not detected +STAT5A MGF, STAT5 ENSG00000126561 Signal transducer and activator of transcription 5A 17 42287547-42311943 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003860, HPA027873, HPA042128, HPA049883, HPA051156 Approved Enhanced Nucleoplasm
Cytosol Breast cancer:5.87e-4 (favourable) Expressed in all Expressed in all adipose tissue: 90.3 Cell line enhanced HDLM-2: 100.4;HEL: 145.8;K-562: 246.3;MOLT-4: 160.1 +WNK4 PRKWNK4 ENSG00000126562 WNK lysine deficient protein kinase 4 17 42780678-42796936 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA016500 Approved Mixed Tissue enhanced kidney: 19.0;prostate: 15.4;rectum: 12.0 colon: 8.8 Cell line enhanced fHDF/TERT166: 26.2;K-562: 34.7;TIME: 29.5;WM-115: 23.9 +BECN1 ATG6, VPS30 ENSG00000126581 Beclin 1 17 42810134-42833350 Predicted intracellular proteins Evidence at protein level CAB010143, HPA028949 Enhanced Expressed in all Expressed in all rectum: 71.3 Expressed in all +PRKCG MGC57564, PKCC, PKCG, SCA14 ENSG00000126583 Protein kinase C gamma 19 53879190-53907652 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB013051, HPA047870, HPA054560 Supported Mixed Tissue enriched 9 cerebral cortex: 40.9 testis: 4.7 Cell line enhanced A549: 2.0;SH-SY5Y: 1.5 +TRAP1 HSP75, HSP90L ENSG00000126602 TNF receptor associated protein 1 16 3651639-3717597 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041082, HPA044227 Enhanced Enhanced Mitochondria Colorectal cancer:1.80e-4 (favourable) Expressed in all Expressed in all fallopian tube: 95.4 Expressed in all +GLIS2 NPHP7 ENSG00000126603 GLIS family zinc finger 2 16 4314761-4339597 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056976 Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:8.06e-6 (favourable), Endometrial cancer:1.59e-5 (unfavourable) Expressed in all Mixed gallbladder: 9.7 Cell line enhanced U-2197: 35.6 +NSRP1 CCDC55, DKFZP434K1421, NSrp70 ENSG00000126653 Nuclear speckle splicing regulatory protein 1 17 30115521-30186475 Predicted intracellular proteins Evidence at protein level HPA015593, HPA015603 Enhanced Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 44.6 Expressed in all +DNAJC8 SPF31 ENSG00000126698 DnaJ heat shock protein family (Hsp40) member C8 1 28199456-28233025 Predicted intracellular proteins Evidence at protein level HPA026275, HPA026283 Approved Enhanced Nucleoplasm Endometrial cancer:6.95e-5 (favourable), Thyroid cancer:2.39e-4 (favourable), Liver cancer:4.71e-4 (unfavourable) Expressed in all Expressed in all lymph node: 93.5 Expressed in all +AHDC1 DJ159A19.3, RP1-159A19.1 ENSG00000126705 AT-hook DNA binding motif containing 1 1 27534035-27604431 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028648, HPA028691 Approved Supported Nucleus Endometrial cancer:1.20e-4 (unfavourable), Head and neck cancer:2.68e-4 (favourable), Ovarian cancer:4.92e-4 (unfavourable) Expressed in all Mixed spleen: 16.0 Mixed +IFI6 6-16, FAM14C, G1P3, IFI-6-16, IFI616 ENSG00000126709 Interferon alpha inducible protein 6 1 27666061-27672218 Predicted membrane proteins Evidence at transcript level HPA005543 Approved Approved Mitochondria Expressed in all Expressed in all placenta: 413.9 Group enriched 6 BJ hTERT+ SV40 Large T+: 1217.0;BJ hTERT+ SV40 Large T+ RasG12V: 1476.2;EFO-21: 494.2;SK-MEL-30: 747.5 +DACH2 ENSG00000126733 Dachshund family transcription factor 2 X 86148458-86832604 Predicted intracellular proteins Evidence at transcript level HPA000258 Approved Not detected Group enriched 8 cerebral cortex: 11.9;epididymis: 4.4;fallopian tube: 5.0 kidney: 0.8 Cell line enriched 8 HAP1: 6.1 +ZNF384 CAGH1A, CIZ, NMP4, NP, TNRC1 ENSG00000126746 Zinc finger protein 384 12 6666477-6689572 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004051 Supported Supported Nucleoplasm Expressed in all Expressed in all endometrium: 66.0 Expressed in all +EMG1 C2F, Grcc2f, NEP1 ENSG00000126749 EMG1, N1-specific pseudouridine methyltransferase 12 6970893-6979941 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039304, HPA039666 Supported Enhanced Nucleus
Nucleoli Renal cancer:2.83e-6 (unfavourable), Liver cancer:3.69e-4 (unfavourable) Expressed in all Expressed in all appendix: 21.0 Expressed in all +SSX1 CT5.1 ENSG00000126752 SSX family member 1 X 48255317-48267444 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045683 Supported Approved Nucleus
Nucleoli Tissue enhanced Tissue enriched 26 testis: 12.7 epididymis: 0.4 Group enriched 9 Daudi: 47.0;Karpas-707: 66.3;U-2197: 20.0 +UXT ART-27, STAP1 ENSG00000126756 Ubiquitously expressed prefoldin like chaperone X 47651798-47659161 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050499, HPA058400 Approved Supported Nucleus
Microtubule organizing center
Cytosol Expressed in all Expressed in all ovary: 184.1 Expressed in all +CFP PFC ENSG00000126759 Complement factor properdin X 47623172-47630305 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced bone marrow: 58.1;spleen: 76.6 appendix: 29.9 Cell line enhanced EFO-21: 21.2;HEL: 4.6;HMC-1: 4.9;NB-4: 7.2;U-937: 6.1 +ELK1 ENSG00000126767 ELK1, ETS transcription factor X 47635521-47650604 Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level CAB003808, HPA036084, HPA064381 Enhanced Enhanced Nucleoplasm Renal cancer:3.25e-5 (unfavourable) Expressed in all Expressed in all ovary: 50.9 Expressed in all +TIMM17B DXS9822, JM3 ENSG00000126768 Translocase of inner mitochondrial membrane 17B X 48893447-48898143 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029093 Approved Approved Microtubules
Mitochondria Cervical cancer:6.63e-4 (favourable), Urothelial cancer:7.88e-4 (favourable) Expressed in all Expressed in all fallopian tube: 43.9 Expressed in all +PCNX4 C14orf135, PCNXL4 ENSG00000126773 Pecanex homolog 4 (Drosophila) 14 60091911-60169133 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002076, HPA003390 Uncertain Approved Cytosol Renal cancer:6.84e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 32.2 Expressed in all +ATG14 ATG14L, KIAA0831 ENSG00000126775 Autophagy related 14 14 55366392-55411858 Predicted intracellular proteins Evidence at protein level CAB037242 Uncertain Liver cancer:1.63e-4 (unfavourable), Renal cancer:1.95e-4 (favourable) Expressed in all Expressed in all bone marrow: 17.1 Expressed in all +KTN1 CG1, KIAA0004, KNT ENSG00000126777 Kinectin 1 14 55559072-55701526 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003178, CAB015331, HPA017876 Enhanced Enhanced Endoplasmic reticulum Renal cancer:1.01e-6 (favourable), Head and neck cancer:6.83e-5 (unfavourable), Liver cancer:3.76e-4 (unfavourable) Expressed in all Expressed in all testis: 268.4 Expressed in all +SIX1 DFNA23 ENSG00000126778 SIX homeobox 1 14 60643415-60658259 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001893, CAB058690 Enhanced Supported Nucleus
Nucleoli Endometrial cancer:8.92e-6 (unfavourable), Lung cancer:3.94e-4 (favourable) Mixed Group enriched 6 cervix, uterine: 21.9;parathyroid gland: 53.5;prostate: 21.2;salivary gland: 21.6;skeletal muscle: 41.5 adipose tissue: 5.6 Cell line enhanced LHCN-M2: 118.6;RH-30: 69.5 +RHOJ ARHJ, FLJ14445, RASL7B, TCL ENSG00000126785 Ras homolog family member J 14 63204114-63293219 Predicted intracellular proteins Evidence at protein level HPA003050 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Renal cancer:1.31e-4 (unfavourable) Expressed in all Mixed endometrium: 48.3 Cell line enhanced AF22: 64.5;HUVEC TERT2: 319.9;TIME: 83.9;WM-115: 109.1 +DLGAP5 DLG1, DLG7, HURP, KIAA0008 ENSG00000126787 DLG associated protein 5 14 55148112-55191678 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005546 Enhanced Supported Microtubule organizing center
Cytosol Liver cancer:1.52e-6 (unfavourable), Pancreatic cancer:9.94e-6 (unfavourable), Endometrial cancer:4.59e-4 (unfavourable), Lung cancer:7.85e-4 (unfavourable) Mixed Tissue enhanced testis: 29.8 lymph node: 20.4 Mixed +L3HYPDH C14orf149, FLJ25436 ENSG00000126790 Trans-L-3-hydroxyproline dehydratase 14 59460363-59484430 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056694 Approved Uncertain Vesicles Renal cancer:1.72e-9 (unfavourable) Expressed in all Expressed in all testis: 32.0 Expressed in all +HSPA2 ENSG00000126803 Heat shock protein family A (Hsp70) member 2 14 64535905-64546173 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000798, HPA052504 Enhanced Approved Approved Nucleoplasm
Vesicles Breast cancer:1.78e-4 (favourable), Lung cancer:9.11e-4 (unfavourable) Expressed in all Tissue enhanced testis: 188.6 cerebral cortex: 96.4 Cell line enhanced A549: 67.9;BEWO: 110.2;BJ hTERT+: 80.5;SCLC-21H: 119.3 +ZBTB1 KIAA0997, ZNF909 ENSG00000126804 Zinc finger and BTB domain containing 1 14 64503712-64533690 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050516 Approved Supported Nucleoplasm
Nuclear membrane Head and neck cancer:4.92e-4 (favourable) Expressed in all Expressed in all bone marrow: 53.5 Expressed in all +TRMT5 KIAA1393, TRM5 ENSG00000126814 TRNA methyltransferase 5 14 60971451-60981358 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000943 Supported Approved Nucleus
Nucleoli Expressed in all Expressed in all testis: 31.3 Expressed in all +SGPP1 ENSG00000126821 Sphingosine-1-phosphate phosphatase 1 14 63684214-63728039 Predicted membrane proteins Evidence at protein level HPA053149, HPA064908 Approved Supported Nucleus Expressed in all Expressed in all placenta: 34.7 Mixed +PLEKHG3 ARHGEF43, KIAA0599 ENSG00000126822 Pleckstrin homology and RhoGEF domain containing G3 14 64704102-64750247 Predicted intracellular proteins Evidence at protein level HPA063455, HPA065323, HPA073702, HPA074734 Enhanced Supported Nucleoplasm
Plasma membrane
Cytokinetic bridge
Centrosome
Cytosol Renal cancer:7.39e-8 (favourable) Expressed in all Expressed in all seminal vesicle: 53.5 Mixed +PZP CPAMD6 ENSG00000126838 PZP, alpha-2-macroglobulin like 12 9148840-9208370 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA041403, HPA041471 Supported Tissue enhanced Tissue enriched 12 liver: 45.9 testis: 3.8 Group enriched 7 HeLa: 3.2;SiHa: 2.6 +PRDM7 ZNF910 ENSG00000126856 PR/SET domain 7 16 90056566-90092072 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059944 Approved Uncertain Nuclear speckles Tissue enriched Tissue enriched 11 testis: 1.1 all non-specific tissues: 0.0 Group enriched 30 REH: 3.8;SK-MEL-30: 2.1 +RHOT1 ARHT1, FLJ11040, MIRO-1 ENSG00000126858 Ras homolog family member T1 17 32142454-32253374 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010687, CAB068223, CAB068224 Enhanced Expressed in all Expressed in all parathyroid gland: 48.8 Expressed in all +EVI2A EVDA, EVI2 ENSG00000126860 Ecotropic viral integration site 2A 17 31317560-31321884 Predicted membrane proteins Evidence at protein level HPA045033, HPA057051 Uncertain Approved Nucleoplasm
Nuclear bodies Renal cancer:2.63e-6 (unfavourable), Melanoma:7.55e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 83.0 Cell line enhanced Karpas-707: 71.2;RPMI-8226: 110.1 +OMG OMGP ENSG00000126861 Oligodendrocyte myelin glycoprotein 17 31272013-31297539 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA008206, HPA012693 Enhanced Group enriched Tissue enriched 318 cerebral cortex: 137.4 bone marrow: 0.4 Not detected +WDR60 FAP163, FLJ10300 ENSG00000126870 WD repeat domain 60 7 158856578-158956747 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020607, HPA021316 Approved Approved Microtubule organizing center Expressed in all Expressed in all testis: 75.5 Expressed in all +AIF1L C9orf58, FLJ12783, IBA2 ENSG00000126878 Allograft inflammatory factor 1 like 9 131096476-131123152 Predicted intracellular proteins Evidence at protein level HPA020522, HPA056852 Enhanced Renal cancer:5.54e-6 (favourable) Expressed in all Tissue enhanced kidney: 287.5;spleen: 288.1 thyroid gland: 155.2 Cell line enhanced AF22: 139.6;NTERA-2: 106.7;RPTEC TERT1: 230.5 +FAM78A C9orf59, FLJ00024 ENSG00000126882 Family with sequence similarity 78 member A 9 131258076-131276547 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021472, HPA023914 Uncertain Uncertain Nucleus
Vesicles Head and neck cancer:2.00e-4 (favourable), Cervical cancer:3.67e-4 (favourable) Expressed in all Mixed lymph node: 27.4 Cell line enhanced BEWO: 37.7;HEL: 34.3;HL-60: 30.4;NB-4: 37.9;THP-1: 35.7;U-937: 27.8 +NUP214 CAIN, CAN, D9S46E, N214 ENSG00000126883 Nucleoporin 214 9 131125561-131234670 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA048789 Supported Nucleus
Vesicles
Focal adhesion sites Renal cancer:2.39e-5 (favourable) Expressed in all Expressed in all testis: 123.0 Expressed in all +CTAG2 CAMEL, CT6.2a, CT6.2b, ESO2, LAGE-1, LAGE-1a, LAGE-1b, LAGE1, MGC138724, MGC3803 ENSG00000126890 Cancer/testis antigen 2 X 154651972-154653579 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA071467 Enhanced Liver cancer:2.35e-4 (unfavourable) Mixed Group enriched 8 fallopian tube: 2.6;heart muscle: 3.2;placenta: 3.6;skeletal muscle: 1.2;testis: 6.0 pancreas: 0.4 Group enriched 29 K-562: 126.4;RPMI-8226: 215.0;SK-BR-3: 146.5;U-266/84: 251.9 +AVPR2 DIR, DIR3, V2R ENSG00000126895 Arginine vasopressin receptor 2 X 153902531-153907166 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA046678 Approved Mixed Tissue enhanced adipose tissue: 5.8 kidney: 2.8 Cell line enhanced EFO-21: 3.0;SCLC-21H: 4.6;U-266/84: 2.7;U-698: 2.8 +SLC10A3 DXS253E, P3 ENSG00000126903 Solute carrier family 10 member 3 X 154487306-154490690 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA021656 Approved Approved Intermediate filaments Colorectal cancer:4.15e-5 (unfavourable), Cervical cancer:4.53e-4 (favourable), Pancreatic cancer:7.22e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 33.0 Expressed in all +MAP2K2 MEK2, PRKMK2 ENSG00000126934 Mitogen-activated protein kinase kinase 2 19 4090321-4124129 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB003835, HPA051993 Supported Supported Cytosol Stomach cancer:5.43e-5 (favourable), Cervical cancer:3.72e-4 (favourable), Head and neck cancer:7.98e-4 (favourable) Expressed in all Expressed in all duodenum: 135.0 Expressed in all +HNRNPH2 FTP3, hnRNPH', HNRPH', HNRPH2 ENSG00000126945 Heterogeneous nuclear ribonucleoprotein H2 X 101408295-101414133 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000914, HPA001359, CAB004436, HPA016884 Supported Enhanced Nucleoplasm Renal cancer:7.37e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 216.1 Expressed in all +ARMCX1 ALEX1, GASP7 ENSG00000126947 Armadillo repeat containing, X-linked 1 X 101550531-101554700 Predicted membrane proteins Evidence at protein level HPA005685, CAB020695 Supported Approved Nucleus
Mitochondria
Cytosol Pancreatic cancer:7.32e-5 (favourable), Cervical cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all ovary: 59.0 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 75.6;RH-30: 84.3 +TMEM35A FLJ14084, TMEM35 ENSG00000126950 Transmembrane protein 35A X 101078720-101096364 Predicted membrane proteins Evidence at protein level HPA048583 Enhanced Supported Vesicles
Focal adhesion sites
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 42.4;seminal vesicle: 65.5 prostate: 33.7 Cell line enhanced HUVEC TERT2: 40.2;SH-SY5Y: 12.9 +NXF5 ENSG00000126952 Nuclear RNA export factor 5 X 101832112-101857577 Disease related genes, Predicted intracellular proteins Evidence at transcript level HPA002079 Uncertain Not detected Not detected cerebral cortex,epididymis,spleen: 0.1 Not detected +TIMM8A DDP, DFN1, MTS ENSG00000126953 Translocase of inner mitochondrial membrane 8A X 101345661-101349196 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003628 Supported Enhanced Mitochondria Breast cancer:7.89e-5 (unfavourable), Endometrial cancer:8.87e-5 (unfavourable), Renal cancer:1.69e-4 (favourable) Expressed in all Mixed liver: 8.9 Expressed in all +ZC4H2 HCA127, KIAA1166, WWS ENSG00000126970 Zinc finger C4H2-type containing X 64915802-65034713 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049584 Approved Approved Vesicles
Microtubules Thyroid cancer:3.51e-5 (unfavourable) Mixed Mixed parathyroid gland: 17.5 Cell line enhanced NTERA-2: 51.9;REH: 36.2 +CANX CNX, IP90, P90 ENSG00000127022 Calnexin 5 179678628-179730925 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004738, HPA009433, HPA009696 Enhanced Enhanced Endoplasmic reticulum Colorectal cancer:1.38e-4 (favourable), Thyroid cancer:3.17e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 294.4 Expressed in all +INTS11 CPSF3L, CPSF73L, FLJ20542, INT11, RC-68 ENSG00000127054 Integrator complex subunit 11 1 1311585-1324691 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028379, HPA029025 Approved Supported Nucleoplasm
Cytosol Liver cancer:7.44e-4 (unfavourable) Expressed in all Expressed in all testis: 77.0 Expressed in all +RGS13 ENSG00000127074 Regulator of G-protein signaling 13 1 192636138-192660306 Predicted intracellular proteins Evidence at protein level HPA044952 Uncertain Mixed Group enriched 6 appendix: 14.3;lymph node: 68.4;tonsil: 36.9 small intestine: 7.1 Cell line enriched 12 Daudi: 37.3 +IPPK C9orf12, FLJ13163, INSP5K2, IP5K, IPK1 ENSG00000127080 Inositol-pentakisphosphate 2-kinase 9 92613184-92670265 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020603 Uncertain Approved Cytosol Urothelial cancer:1.28e-4 (unfavourable) Mixed Mixed skin: 34.2 Expressed in all +ZNF484 BA526D8.4, FLJ33884 ENSG00000127081 Zinc finger protein 484 9 92845031-92878038 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028973 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Mixed Mixed parathyroid gland: 6.9 Mixed +OMD osteoadherin, SLRR2C ENSG00000127083 Osteomodulin 9 92414245-92424461 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA005731, HPA069948 Approved Approved Nucleoli fibrillar center
Endoplasmic reticulum Mixed Mixed cervix, uterine: 36.4 Group enriched 13 ASC diff: 6.2;ASC TERT1: 5.9 +FGD3 FLJ00004, ZFYVE5 ENSG00000127084 FYVE, RhoGEF and PH domain containing 3 9 92947451-93036236 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020963, HPA021018 Approved Approved Nucleus
Cytosol Head and neck cancer:2.23e-7 (favourable), Cervical cancer:5.51e-4 (favourable) Expressed in all Tissue enhanced lymph node: 31.4 spleen: 29.0 Cell line enhanced HMC-1: 35.3;Karpas-707: 40.4;RT4: 25.9 +HIVEP3 FLJ16752, KBP-1, KBP1, KIAA1555, KRC, Schnurri-3, SHN3, ZAS3, ZNF40C ENSG00000127124 Human immunodeficiency virus type I enhancer binding protein 3 1 41506365-42035925 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005728 Approved Supported Nucleoplasm Mixed Mixed skin: 5.6 Cell line enhanced HDLM-2: 17.9 +PPCS FLJ11838 ENSG00000127125 Phosphopantothenoylcysteine synthetase 1 42456117-42473385 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031361, HPA031363 Approved Approved Nucleus
Nucleoli fibrillar center
Mitochondria Liver cancer:5.96e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 110.6 Expressed in all +EDN2 ET2 ENSG00000127129 Endothelin 2 1 41478775-41484673 Predicted secreted proteins Evidence at protein level HPA028459 Uncertain Approved Cytosol Endometrial cancer:2.85e-4 (unfavourable), Pancreatic cancer:5.81e-4 (unfavourable) Tissue enhanced Tissue enhanced esophagus: 10.6;small intestine: 18.1 epididymis: 5.5 Cell line enhanced CAPAN-2: 12.3;EFO-21: 32.7;SCLC-21H: 19.7;SK-BR-3: 31.2;U-2 OS: 16.7 +BCL11B CTIP-2, CTIP2, hRIT1-alpha, ZNF856B ENSG00000127152 B-cell CLL/lymphoma 11B 14 99169287-99271524 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049117 Enhanced Supported Approved Nucleus
Nucleoli fibrillar center Urothelial cancer:7.48e-4 (favourable) Mixed Tissue enhanced lymph node: 12.2;skin: 18.7 tonsil: 7.4 Cell line enriched 6 MOLT-4: 41.1 +COX7C ENSG00000127184 Cytochrome c oxidase subunit 7C 5 86617904-86620962 Predicted membrane proteins, Transporters Evidence at protein level HPA046647 Approved Renal cancer:1.23e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 821.9 Expressed in all +TRAF2 TRAP3 ENSG00000127191 TNF receptor associated factor 2 9 136881912-136926607 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004603, HPA009972, HPA010634 Uncertain Enhanced Cytosol Renal cancer:2.09e-4 (unfavourable), Liver cancer:3.06e-4 (unfavourable), Colorectal cancer:9.32e-4 (unfavourable) Expressed in all Expressed in all lymph node: 22.5 Expressed in all +ABHD8 FLJ11743, MGC14280, MGC2512 ENSG00000127220 Abhydrolase domain containing 8 19 17292131-17310236 Predicted intracellular proteins Evidence at protein level HPA037658, HPA058209 Approved Approved Nucleoplasm
Nuclear bodies Pancreatic cancer:3.04e-5 (favourable), Colorectal cancer:5.25e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 28.5 Cell line enhanced PC-3: 48.7 +MASP1 CRARF, MASP, PRSS5 ENSG00000127241 Mannan binding lectin serine peptidase 1 3 187217285-187292022 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001617, HPA009641 Supported Supported Nucleoplasm
Cytosol Liver cancer:2.20e-4 (favourable) Group enriched Tissue enhanced cervix, uterine: 135.4 endometrium: 94.8 Group enriched 8 BJ: 107.2;BJ hTERT+: 389.0 +ATP13A4 DKFZp761I1011, FLJ37958 ENSG00000127249 ATPase 13A4 3 193402077-193593111 Disease related genes, Predicted membrane proteins Evidence at protein level HPA051932 Approved Nucleoplasm Head and neck cancer:3.91e-4 (favourable) Tissue enhanced Tissue enhanced epididymis: 87.9;parathyroid gland: 131.5;thyroid gland: 68.5 lung: 53.7 Cell line enriched 7 SCLC-21H: 4.6 +HRASLS H-REV107, HRASLS1 ENSG00000127252 HRAS like suppressor 3 193241125-193277738 Predicted membrane proteins Evidence at transcript level HPA051179 Uncertain Approved Focal adhesion sites
Cytosol Testis cancer:4.36e-4 (favourable) Mixed Group enriched 6 skeletal muscle: 27.2;testis: 95.8 thyroid gland: 10.0 Cell line enhanced HAP1: 11.5;PC-3: 20.0;SCLC-21H: 22.9;U-2 OS: 12.2;U-251 MG: 12.7 +HELB ENSG00000127311 DNA helicase B 12 66302545-66347645 Enzymes, Predicted intracellular proteins Evidence at protein level Mixed Mixed lymph node: 3.5 Mixed +RAP1B DKFZp586H0723, K-REV, RAL1B ENSG00000127314 RAP1B, member of RAS oncogene family 12 68610839-68671901 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Renal cancer:8.08e-4 (unfavourable) Expressed in all Expressed in all lymph node: 243.9 Expressed in all +IL22 IL-21, IL-22, IL-D110, IL-TIF, ILTIF, MGC79382, MGC79384, TIFa, TIFIL-23, zcyto18 ENSG00000127318 Interleukin 22 12 68248242-68253607 Predicted secreted proteins Evidence at protein level Not detected Not detected appendix,urinary bladder: 0.8 Not detected +TSPAN8 CO-029, TM4SF3 ENSG00000127324 Tetraspanin 8 12 71125085-71441898 Cancer-related genes, Predicted membrane proteins Evidence at protein level CAB026009, HPA044337 Enhanced Approved Nucleoplasm Urothelial cancer:7.36e-5 (favourable), Renal cancer:9.66e-5 (unfavourable) Tissue enhanced Tissue enhanced colon: 910.6;duodenum: 905.9;rectum: 911.5;small intestine: 909.2 stomach: 573.4 Cell line enhanced CACO-2: 36.0;HeLa: 34.8;PC-3: 151.7;RT4: 30.6 +BEST3 MGC13168, MGC40411, VMD2L3 ENSG00000127325 Bestrophin 3 12 69643360-69699476 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA054582 Approved Tissue enriched Tissue enhanced cerebral cortex: 16.3;skeletal muscle: 12.2 testis: 5.6 Group enriched 13 REH: 32.4;RPMI-8226: 26.4;U-698: 43.2 +RAB3IP FLJ22548, RABIN3, RABIN8 ENSG00000127328 RAB3A interacting protein 12 69738681-69823204 Predicted intracellular proteins Evidence at protein level HPA039794 Uncertain Approved Intermediate filaments Renal cancer:5.68e-13 (favourable) Mixed Tissue enhanced testis: 134.1 epididymis: 53.2 Expressed in all +PTPRB PTPB ENSG00000127329 Protein tyrosine phosphatase, receptor type B 12 70515866-70637440 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004782, HPA067868 Uncertain Approved Vesicles
Plasma membrane
Cell Junctions Renal cancer:1.02e-4 (favourable), Liver cancer:6.05e-4 (favourable) Expressed in all Mixed lung: 54.0 Cell line enhanced EFO-21: 22.9;HUVEC TERT2: 51.3;TIME: 74.1 +DYRK2 ENSG00000127334 Dual specificity tyrosine phosphorylation regulated kinase 2 12 67648338-67665406 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027230, HPA056902 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all small intestine: 31.0 Expressed in all +YEATS4 GAS41, NuBI-1, YAF9 ENSG00000127337 YEATS domain containing 4 12 69359703-69390796 Predicted intracellular proteins Evidence at protein level HPA072532 Approved Nucleoplasm
Nuclear membrane Liver cancer:3.52e-6 (unfavourable) Expressed in all Expressed in all testis: 69.3 Expressed in all +TAS2R3 T2R3 ENSG00000127362 Taste 2 receptor member 3 7 141764097-141765197 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected ovary: 0.5 Not detected +TAS2R4 T2R4 ENSG00000127364 Taste 2 receptor member 4 7 141778442-141780819 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Mixed skin: 1.7 Not detected +TAS2R5 T2R5 ENSG00000127366 Taste 2 receptor member 5 7 141790217-141791367 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced skin: 5.0 epididymis: 3.4 Cell line enhanced hTCEpi: 3.8 +CRYGN ENSG00000127377 Crystallin gamma N 7 151428835-151440813 Predicted intracellular proteins Evidence at transcript level HPA050788 Uncertain Tissue enriched Group enriched 6 seminal vesicle: 10.2;thyroid gland: 32.3 parathyroid gland: 3.4 Cell line enhanced CACO-2: 1.1;HHSteC: 1.4;SCLC-21H: 2.0 +LRRC61 FLJ31392, HSPC295, MGC3036 ENSG00000127399 Leucine rich repeat containing 61 7 150322639-150338150 Predicted intracellular proteins Evidence at transcript level HPA019355 Approved Approved Nucleoplasm Glioma:2.15e-5 (unfavourable), Stomach cancer:2.85e-4 (favourable) Expressed in all Mixed fallopian tube: 22.6 Cell line enhanced HDLM-2: 71.3;NTERA-2: 64.8 +TRPV5 CaT2, ECAC1 ENSG00000127412 Transient receptor potential cation channel subfamily V member 5 7 142908101-142933808 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA063175 Approved Not detected Not detected kidney: 0.5 Not detected +IDUA MPS1 ENSG00000127415 Iduronidase, alpha-L- 4 986997-1004506 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025901, HPA046979, HPA054254 Enhanced Supported Vesicles Renal cancer:7.87e-5 (unfavourable), Urothelial cancer:8.04e-5 (favourable), Colorectal cancer:3.13e-4 (unfavourable) Expressed in all Expressed in all spleen: 16.5 Cell line enhanced U-266/70: 43.1 +FGFRL1 ENSG00000127418 Fibroblast growth factor receptor-like 1 4 1009936-1026897 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB026019, HPA068828 Approved Supported Vesicles Expressed in all Expressed in all thyroid gland: 67.6 Mixed +TMEM175 MGC4618 ENSG00000127419 Transmembrane protein 175 4 932387-958656 Predicted membrane proteins, Transporters Evidence at protein level HPA057160 Approved Approved Nucleus
Nuclear membrane Pancreatic cancer:9.85e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 20.7 Expressed in all +AUNIP AIBp, C1orf135, MGC2603 ENSG00000127423 Aurora kinase A and ninein interacting protein 1 25831913-25859458 Predicted intracellular proteins Evidence at protein level HPA028730 Uncertain Enhanced Centrosome Endometrial cancer:3.94e-4 (unfavourable) Mixed Tissue enriched 7 testis: 29.0 bone marrow: 3.8 Mixed +PIN1 dod ENSG00000127445 Peptidylprolyl cis/trans isomerase, NIMA-interacting 1 19 9835257-9849682 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB004528, CAB009326, HPA068650 Approved Enhanced Nucleoplasm
Cytosol Renal cancer:7.80e-5 (favourable), Pancreatic cancer:3.25e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 136.9 Expressed in all +FBXL12 Fbl12, FLJ20188 ENSG00000127452 F-box and leucine rich repeat protein 12 19 9810267-9827816 Predicted intracellular proteins Evidence at protein level HPA002843 Approved Mitochondria Liver cancer:1.41e-4 (unfavourable), Head and neck cancer:3.21e-4 (favourable), Melanoma:4.96e-4 (unfavourable) Expressed in all Expressed in all placenta: 21.7 Expressed in all +EMC1 KIAA0090 ENSG00000127463 ER membrane protein complex subunit 1 1 19215664-19251552 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA048904 Approved Approved Microtubules
Cytokinetic bridge Liver cancer:8.56e-6 (unfavourable), Urothelial cancer:1.43e-4 (unfavourable) Expressed in all Expressed in all placenta: 34.4 Expressed in all +PLA2G5 ENSG00000127472 Phospholipase A2 group V 1 20028179-20091190 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA053361 Approved Group enriched Tissue enhanced heart muscle: 48.6 seminal vesicle: 19.8 Cell line enhanced U-138 MG: 1.0;U-2197: 2.1 +UBR4 KIAA0462, KIAA1307, RBAF600, ZUBR1 ENSG00000127481 Ubiquitin protein ligase E3 component n-recognin 4 1 19074506-19210276 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013394, HPA021046 Approved Supported Nucleoplasm
Centrosome
Cytosol Expressed in all Expressed in all skin: 90.3 Expressed in all +HP1BP3 HP1-BP74 ENSG00000127483 Heterochromatin protein 1 binding protein 3 1 20742661-20787323 Predicted intracellular proteins Evidence at protein level HPA028215, HPA054295 Supported Supported Nuclear speckles Liver cancer:2.76e-4 (unfavourable) Expressed in all Expressed in all endometrium: 192.4 Expressed in all +ADGRE2 CD312, EMR2 ENSG00000127507 Adhesion G protein-coupled receptor E2 19 14732393-14778541 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA055200 Uncertain Vesicles Renal cancer:4.35e-6 (unfavourable) Mixed Tissue enhanced appendix: 27.0;spleen: 15.4 adipose tissue: 6.0 Cell line enhanced HEL: 10.6;HMC-1: 16.0;U-937: 11.8 +SIN3B KIAA0700 ENSG00000127511 SIN3 transcription regulator family member B 19 16829400-16880353 Predicted intracellular proteins Evidence at protein level HPA050329 Uncertain Approved Nucleoplasm
Plasma membrane Prostate cancer:3.58e-4 (unfavourable), Pancreatic cancer:4.37e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 112.3 Expressed in all +OR7A10 ENSG00000127515 Olfactory receptor family 7 subfamily A member 10 19 14840948-14841877 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +SLC35E1 FLJ14251 ENSG00000127526 Solute carrier family 35 member E1 19 16549831-16572382 Predicted membrane proteins, Transporters Evidence at protein level HPA016570, HPA062214 Approved Enhanced Golgi apparatus Expressed in all Expressed in all parathyroid gland: 28.5 Expressed in all +EPS15L1 eps15R ENSG00000127527 Epidermal growth factor receptor pathway substrate 15 like 1 19 16355239-16472085 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019237, HPA055309 Uncertain Approved Vesicles Renal cancer:8.10e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 26.0 Expressed in all +KLF2 LKLF ENSG00000127528 Kruppel like factor 2 19 16324817-16327874 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055964 Approved Approved Nucleoplasm Liver cancer:8.55e-4 (favourable) Expressed in all Expressed in all adipose tissue: 115.9 Cell line enhanced TIME: 57.5;U-266/70: 36.1;U-266/84: 34.1 +OR7C2 OR19-18, OR7C3 ENSG00000127529 Olfactory receptor family 7 subfamily C member 2 19 14941489-14942448 G-protein coupled receptors, Predicted membrane proteins No evidence HPA047295 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR7C1 OR19-5, OR7C4 ENSG00000127530 Olfactory receptor family 7 subfamily C member 1 19 14799146-14800211 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047127 Uncertain Tissue enriched Tissue enhanced epididymis: 3.5;parathyroid gland: 5.0;testis: 3.9 seminal vesicle: 1.5 Not detected +F2RL3 PAR4 ENSG00000127533 F2R like thrombin/trypsin receptor 3 19 16888860-16892606 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Renal cancer:6.25e-4 (favourable) Mixed Mixed thyroid gland: 7.7 Group enriched 8 HEL: 26.3;HMC-1: 10.0 +UQCR11 QCR10, UQCR ENSG00000127540 Ubiquinol-cytochrome c reductase, complex III subunit XI 19 1597172-1605490 Predicted membrane proteins Evidence at protein level Endometrial cancer:1.23e-4 (favourable), Renal cancer:1.65e-4 (favourable), Pancreatic cancer:1.86e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 111.9 Expressed in all +GFER ALR, ERV1, HERV1, HPO1, HPO2, HSS ENSG00000127554 Growth factor, augmenter of liver regeneration 16 1984207-1987749 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041227, HPA063553 Approved Enhanced Mitochondria
Cytosol Renal cancer:4.06e-4 (favourable) Expressed in all Expressed in all small intestine: 50.0 Expressed in all +SYNGR3 ENSG00000127561 Synaptogyrin 3 16 1989660-1994275 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB034278, HPA042842 Enhanced Approved Plasma membrane Renal cancer:7.12e-7 (favourable), Cervical cancer:6.92e-4 (favourable) Mixed Tissue enriched 7 cerebral cortex: 82.6 parathyroid gland: 12.6 Cell line enhanced HDLM-2: 45.7;HMC-1: 26.7;U-266/70: 30.7 +PKMYT1 MYT1, PPP1R126 ENSG00000127564 Protein kinase, membrane associated tyrosine/threonine 1 16 2968024-2980539 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA068860 Supported Nucleus
Nucleoli
Golgi apparatus Lung cancer:3.37e-4 (unfavourable), Liver cancer:8.33e-4 (unfavourable) Mixed Tissue enhanced bone marrow: 17.0;testis: 27.7 lymph node: 9.7 Mixed +WFIKKN1 C16orf12, RJD2, WFDC20A, WFIKKN ENSG00000127578 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 16 629239-634116 Predicted secreted proteins Evidence at protein level CAB025858, HPA043362, HPA044237 Uncertain Mixed Not detected cerebral cortex,endometrium,lung,spleen: 0.1 Cell line enhanced EFO-21: 4.2;NTERA-2: 1.3 +WDR24 C16orf21, DKFZp434F054, JFP7 ENSG00000127580 WD repeat domain 24 16 684622-690444 Predicted intracellular proteins Evidence at protein level HPA039506 Approved Renal cancer:3.75e-6 (favourable) Expressed in all Expressed in all testis: 11.8 Expressed in all +FBXL16 C16orf22, Fbl16, MGC33974 ENSG00000127585 F-box and leucine rich repeat protein 16 16 692498-705829 Predicted intracellular proteins Evidence at protein level HPA039504, HPA056354 Enhanced Endometrial cancer:6.24e-5 (unfavourable), Pancreatic cancer:7.34e-5 (favourable), Renal cancer:1.87e-4 (favourable) Expressed in all Tissue enriched 23 cerebral cortex: 186.4 testis: 8.0 Cell line enhanced AN3-CA: 16.9;SCLC-21H: 35.4;SH-SY5Y: 23.8 +CHTF18 C16orf41, C321D2.4, CHL12, Ctf18 ENSG00000127586 Chromosome transmission fidelity factor 18 16 788046-800737 Predicted intracellular proteins Evidence at protein level HPA040976, HPA056209 Enhanced Nucleoplasm
Cytosol Renal cancer:1.43e-8 (unfavourable), Urothelial cancer:2.78e-4 (favourable) Expressed in all Mixed testis: 4.7 Cell line enhanced BEWO: 46.5 +GNG13 G(gamma)13, h2-35 ENSG00000127588 G protein subunit gamma 13 16 798041-800733 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA046272 Approved Mixed Tissue enhanced cerebral cortex: 2.5;duodenum: 1.4;small intestine: 1.4 colon: 0.7 Cell line enhanced CACO-2: 8.6;HEK 293: 8.3;MCF7: 10.0 +MACF1 ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF ENSG00000127603 Microtubule-actin crosslinking factor 1 1 39081316-39487177 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013713, HPA068064, HPA068103 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Renal cancer:2.77e-5 (favourable) Expressed in all Expressed in all lung: 137.2 Expressed in all +SMARCA4 BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2 ENSG00000127616 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 19 10961001-11065395 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004208 Supported Supported Nucleoplasm Liver cancer:1.11e-4 (unfavourable) Expressed in all Expressed in all testis: 39.5 Expressed in all +KDM4B JMJD2B, KIAA0876, TDRD14B ENSG00000127663 Lysine demethylase 4B 19 4969113-5153595 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062872 Supported Nucleus
Cytosol Endometrial cancer:4.25e-7 (favourable), Melanoma:2.13e-4 (unfavourable), Colorectal cancer:2.74e-4 (unfavourable), Breast cancer:7.39e-4 (favourable) Expressed in all Expressed in all thyroid gland: 19.9 Expressed in all +TICAM1 MGC35334, PRVTIRB, TICAM-1, TRIF ENSG00000127666 Toll like receptor adaptor molecule 1 19 4815932-4831704 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042460 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Lung cancer:3.48e-4 (unfavourable), Endometrial cancer:4.81e-4 (favourable) Expressed in all Expressed in all esophagus: 22.0 Mixed +METTL25 C12orf26, FLJ22789 ENSG00000127720 Methyltransferase like 25 12 82358497-82479236 Predicted intracellular proteins Evidence at protein level HPA039534, HPA041207 Uncertain Uncertain Plasma membrane
Mitochondria
Cytosol Expressed in all Mixed testis: 10.9 Mixed +IL17B IL-17B, IL-20, MGC138900, MGC138901, NIRF, ZCYTO7 ENSG00000127743 Interleukin 17B 5 149371324-149404202 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA042441 Uncertain Mixed Tissue enhanced breast: 4.0 smooth muscle: 3.3 Cell line enhanced HEL: 1.2 +EMC6 MGC2963, TMEM93 ENSG00000127774 ER membrane protein complex subunit 6 17 3668815-3669668 Predicted membrane proteins Evidence at protein level HPA062681 Uncertain Approved Nucleus
Centrosome Lung cancer:9.39e-5 (unfavourable), Cervical cancer:7.73e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 49.2 Expressed in all +OR1E2 OR17-135, OR17-93, OR1E4 ENSG00000127780 Olfactory receptor family 1 subfamily E member 2 17 3432870-3433841 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +METTL16 METT10D, MGC3329 ENSG00000127804 Methyltransferase like 16 17 2405562-2511891 Predicted intracellular proteins Evidence at protein level HPA020352, HPA059798 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:3.06e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.4 Expressed in all +TUBA4A FLJ30169, H2-ALPHA, TUBA1 ENSG00000127824 Tubulin alpha 4a 2 219249711-219278170 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004621, CAB005887, HPA039247, HPA043684, HPA063394 Approved Enhanced Microtubules Liver cancer:4.54e-6 (unfavourable) Expressed in all Expressed in all skin: 181.8 Cell line enhanced HBEC3-KT: 297.7 +VIL1 D2S1471, VIL ENSG00000127831 Villin 1 2 218419092-218453295 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002452, HPA006884, HPA006885 Enhanced Enhanced Plasma membrane Tissue enhanced Group enriched 7 colon: 173.7;duodenum: 398.5;rectum: 199.6;small intestine: 480.0 gallbladder: 44.7 Group enriched 91 CACO-2: 628.4;Hep G2: 245.1 +AAMP ENSG00000127837 Angio associated migratory cell protein 2 218264123-218270257 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017717, HPA031868 Approved Supported Microtubules
Cytosol Liver cancer:4.94e-7 (unfavourable), Endometrial cancer:1.62e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 115.1 Expressed in all +PNKD BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, PDC, PKND1, TAHCCP2 ENSG00000127838 Paroxysmal nonkinesigenic dyskinesia 2 218270392-218346793 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010134, HPA017068 Approved Enhanced Mitochondria Renal cancer:5.13e-5 (unfavourable) Expressed in all Expressed in all prostate: 119.5 Expressed in all +TNFRSF19 TAJ, TAJ-alpha, TRADE, TROY ENSG00000127863 TNF receptor superfamily member 19 13 23570370-23676104 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA010135 Approved Nucleoplasm
Mitochondria Renal cancer:9.13e-7 (favourable), Lung cancer:3.87e-4 (favourable) Expressed in all Tissue enhanced skin: 128.9 fallopian tube: 50.5 Cell line enhanced BJ hTERT+: 65.9;fHDF/TERT166: 48.4;Hep G2: 58.9;SK-MEL-30: 111.1;WM-115: 86.3 +RNF6 DKFZp686P0776 ENSG00000127870 Ring finger protein 6 13 26132115-26222493 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039343, HPA040048 Approved Supported Nuclear membrane Cervical cancer:3.07e-4 (unfavourable) Expressed in all Expressed in all testis: 61.0 Mixed +ECHS1 SCEH ENSG00000127884 Enoyl-CoA hydratase, short chain 1 10 133362480-133373689 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003783, HPA021995, HPA022476 Enhanced Enhanced Mitochondria Renal cancer:8.57e-5 (favourable) Expressed in all Expressed in all liver: 438.0 Expressed in all +ZNF835 BC37295_3 ENSG00000127903 Zinc finger protein 835 19 56661981-56671783 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA051136 Uncertain Approved Microtubules Mixed Mixed ovary: 5.3 Cell line enhanced BEWO: 2.3;EFO-21: 1.9;NTERA-2: 4.7;SH-SY5Y: 2.6;U-266/84: 2.8 +AKAP9 AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO ENSG00000127914 A-kinase anchoring protein 9 7 91940867-92110673 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008548, CAB012909, HPA026109 Enhanced Enhanced Golgi apparatus
Vesicles
Centrosome Renal cancer:2.10e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 37.8 Expressed in all +GNG11 GNGT11 ENSG00000127920 G protein subunit gamma 11 7 93921699-93928610 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA045255 Uncertain Expressed in all Expressed in all placenta: 123.2 Cell line enhanced EFO-21: 204.6;HUVEC TERT2: 287.9;U-87 MG: 180.8 +SEM1 DSS1, ECD, SHFD1, Shfdg1, SHFM1, SHSF1 ENSG00000127922 SEM1, 26S proteasome complex subunit 7 96481626-96709891 Predicted intracellular proteins Evidence at protein level HPA020429, HPA072648 Uncertain Approved Cytosol Urothelial cancer:8.00e-5 (favourable), Ovarian cancer:2.52e-4 (favourable), Renal cancer:7.19e-4 (unfavourable) Expressed in all Expressed in all testis: 223.1 Expressed in all +GNGT1 GNG1 ENSG00000127928 G protein subunit gamma transducin 1 7 93591573-93911265 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA042721 Supported Mixed Tissue enriched 6 placenta: 3.9 urinary bladder: 0.6 Cell line enhanced EFO-21: 8.7;SCLC-21H: 3.1;T-47d: 4.8 +HIP1 ILWEQ ENSG00000127946 Huntingtin interacting protein 1 7 75533300-75738962 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA013606, CAB015334, CAB016402, HPA017964 Enhanced Enhanced Vesicles Expressed in all Mixed testis: 35.2 Mixed +PTPN12 PTP-PEST, PTPG1 ENSG00000127947 Protein tyrosine phosphatase, non-receptor type 12 7 77537275-77640071 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007097 Approved Approved Plasma membrane
Cytosol Renal cancer:7.27e-6 (unfavourable), Cervical cancer:1.15e-4 (unfavourable), Pancreatic cancer:2.01e-4 (unfavourable), Liver cancer:8.78e-4 (unfavourable) Expressed in all Expressed in all placenta: 107.2 Expressed in all +POR CYPOR, FLJ26468 ENSG00000127948 Cytochrome p450 oxidoreductase 7 75899200-75986855 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB004372, HPA010136 Enhanced Approved Nucleoplasm
Vesicles
Cytosol Glioma:5.23e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 220.8 Expressed in all +FGL2 pT49, T49 ENSG00000127951 Fibrinogen like 2 7 77193371-77199848 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA021011, HPA026682 Enhanced Expressed in all Expressed in all spleen: 232.5 Cell line enhanced RPTEC TERT1: 4.2;U-937: 4.7;WM-115: 6.3 +STYXL1 DUSP24, MK-STYX ENSG00000127952 Serine/threonine/tyrosine interacting like 1 7 75996338-76048004 Predicted intracellular proteins Evidence at transcript level HPA050261 Uncertain Approved Nuclear speckles Urothelial cancer:8.22e-4 (favourable) Expressed in all Expressed in all fallopian tube: 46.0 Expressed in all +STEAP4 FLJ23153, STAMP2, TIARP, TNFAIP9 ENSG00000127954 STEAP4 metalloreductase 7 88270892-88306891 Predicted membrane proteins, Transporters Evidence at protein level HPA075871 Supported Golgi apparatus Liver cancer:2.97e-4 (favourable), Stomach cancer:5.77e-4 (unfavourable) Tissue enhanced Expressed in all adipose tissue: 130.7 Group enriched 6 HSkMC: 88.7;SiHa: 126.7;U-2197: 154.7 +GNAI1 ENSG00000127955 G protein subunit alpha i1 7 80133955-80219402 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022449, HPA042141 Approved Supported Nucleus
Nucleoli
Centrosome Melanoma:5.09e-4 (unfavourable), Stomach cancer:6.47e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 94.5 Mixed +PEX1 ZWS, ZWS1 ENSG00000127980 Peroxisomal biogenesis factor 1 7 92487020-92528531 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA020235 Approved Supported Peroxisomes Expressed in all Expressed in all parathyroid gland: 22.5 Expressed in all +MTERF1 MTERF ENSG00000127989 Mitochondrial transcription termination factor 1 7 91692008-91880720 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044894, HPA069560 Uncertain Supported Mitochondria Expressed in all Expressed in all lymph node: 16.4 Expressed in all +SGCE DYT11 ENSG00000127990 Sarcoglycan epsilon 7 94585230-94656209 Disease related genes, Predicted membrane proteins Evidence at protein level HPA074790 Approved Nucleoplasm
Golgi apparatus
Vesicles
Plasma membrane Head and neck cancer:1.61e-5 (unfavourable), Stomach cancer:1.35e-4 (unfavourable) Expressed in all Mixed ovary: 133.2 Mixed +RBM48 C7orf64, DKFZp564O0523, HSPC304 ENSG00000127993 RNA binding motif protein 48 7 92528773-92538005 Predicted intracellular proteins Evidence at protein level HPA021777, HPA025306 Uncertain Enhanced Nucleoplasm Liver cancer:3.17e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 19.8 Expressed in all +CASD1 C7orf12, FLJ21213, FLJ21879 ENSG00000127995 CAS1 domain containing 1 7 94509219-94557019 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044404 Uncertain Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 38.8 Mixed +ZNF780B ZNF779 ENSG00000128000 Zinc finger protein 780B 19 40028260-40056209 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003311 Uncertain Approved Nucleus
Centrosome Expressed in all Mixed thyroid gland: 8.0 Mixed +LRFN1 KIAA1484, SALM2 ENSG00000128011 Leucine rich repeat and fibronectin type III domain containing 1 19 39306568-39315336 Predicted membrane proteins Evidence at protein level Endometrial cancer:3.31e-5 (unfavourable), Ovarian cancer:3.13e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 5.5 spleen: 2.2 Cell line enhanced CACO-2: 14.4;HEK 293: 19.2 +ZFP36 G0S24, NUP475, RNF162A, TIS11, TTP ENSG00000128016 ZFP36 ring finger protein 19 39406813-39409412 Predicted intracellular proteins Evidence at transcript level HPA006009 Approved Approved Vesicles
Intermediate filaments Expressed in all Expressed in all gallbladder: 928.0 Expressed in all +SRD5A3 FLJ13352, SRD5A2L, SRD5A2L1 ENSG00000128039 Steroid 5 alpha-reductase 3 4 55346109-55373096 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA027006 Uncertain Approved Plasma membrane
Cytosol Renal cancer:4.85e-10 (unfavourable), Liver cancer:1.80e-6 (unfavourable), Endometrial cancer:9.39e-4 (favourable) Expressed in all Expressed in all gallbladder: 28.2 Expressed in all +SPINK2 HUSI-II ENSG00000128040 Serine peptidase inhibitor, Kazal type 2 4 56809860-56821742 Predicted secreted proteins Evidence at protein level CAB020824, HPA026813 Enhanced Lung cancer:2.82e-4 (favourable) Group enriched Tissue enriched 15 epididymis: 6416.1 testis: 428.6 Cell line enhanced Daudi: 15.0;NB-4: 11.4;U-266/70: 67.9 +RASL11B ENSG00000128045 RAS like family 11 member B 4 52862290-52866835 Predicted intracellular proteins Evidence at transcript level HPA057803 Uncertain Approved Nuclear bodies Mixed Tissue enhanced ovary: 26.0;parathyroid gland: 30.1 cerebral cortex: 13.5 Cell line enhanced BEWO: 13.0;NTERA-2: 14.5;SH-SY5Y: 38.8 +PAICS ADE2H1, AIRC, PAIS ENSG00000128050 Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 56435741-56464579 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035895, HPA041538 Uncertain Approved Cytosol Renal cancer:5.85e-5 (unfavourable), Liver cancer:1.50e-4 (unfavourable), Thyroid cancer:2.41e-4 (unfavourable), Ovarian cancer:8.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 74.0 Expressed in all +KDR CD309, FLK1, VEGFR, VEGFR2 ENSG00000128052 Kinase insert domain receptor 4 55078477-55125589 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level CAB004028 Enhanced Supported Plasma membrane Renal cancer:7.26e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 119.2 thyroid gland: 54.7 Group enriched 9 HUVEC TERT2: 178.6;TIME: 148.0 +PPAT GPAT, PRAT ENSG00000128059 Phosphoribosyl pyrophosphate amidotransferase 4 56393362-56435615 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036091, HPA036092 Approved Approved Midbody ring Liver cancer:1.14e-8 (unfavourable), Endometrial cancer:5.15e-5 (unfavourable), Thyroid cancer:1.95e-4 (unfavourable), Renal cancer:8.34e-4 (unfavourable) Expressed in all Mixed testis: 16.1 Expressed in all +TUBGCP6 DJ402G11.6, GCP6, KIAA1669 ENSG00000128159 Tubulin gamma complex associated protein 6 22 50217689-50244992 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043928 Approved Urothelial cancer:3.18e-5 (favourable), Pancreatic cancer:5.75e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 28.2 Expressed in all +ADM2 AM2, FLJ21135 ENSG00000128165 Adrenomedullin 2 22 50481556-50486440 Predicted secreted proteins Evidence at transcript level Thyroid cancer:2.72e-4 (unfavourable) Mixed Tissue enhanced thyroid gland: 19.2 kidney: 5.8 Cell line enhanced HHSteC: 30.8;Karpas-707: 27.1 +DGCR6L FLJ10666 ENSG00000128185 DiGeorge syndrome critical region gene 6-like 22 20314276-20320080 Predicted intracellular proteins Evidence at protein level Cervical cancer:3.82e-5 (favourable), Lung cancer:5.37e-4 (favourable) Expressed in all Expressed in all testis: 97.0 Expressed in all +DGCR8 C22orf12, DGCRK6, Gy1, pasha ENSG00000128191 DGCR8, microprocessor complex subunit 22 20080232-20111877 Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:1.08e-4 (unfavourable), Renal cancer:5.67e-4 (unfavourable) Expressed in all Expressed in all testis: 22.1 Expressed in all +ASPHD2 FLJ39838 ENSG00000128203 Aspartate beta-hydroxylase domain containing 2 22 26429273-26445015 Predicted membrane proteins Evidence at protein level HPA000820 Uncertain Renal cancer:4.06e-5 (unfavourable) Mixed Tissue enhanced cerebral cortex: 12.8 stomach: 7.8 Cell line enhanced Karpas-707: 15.8 +VPREB3 8HS20 ENSG00000128218 Pre-B lymphocyte 3 22 23752743-23754468 Predicted secreted proteins Evidence at protein level HPA003041 Supported Expressed in all Tissue enhanced lymph node: 117.3;tonsil: 95.8 spleen: 61.1 Cell line enhanced Daudi: 168.5;REH: 255.6;U-698: 50.4 +SDF2L1 AP000553.C22.4, OTTHUMT00000075032 ENSG00000128228 Stromal cell derived factor 2 like 1 22 21642261-21644298 Predicted secreted proteins Evidence at protein level HPA005638 Approved Endometrial cancer:4.98e-5 (favourable) Expressed in all Expressed in all thyroid gland: 45.4 Expressed in all +GAL3ST1 CST ENSG00000128242 Galactose-3-O-sulfotransferase 1 22 30554635-30574587 Enzymes, Predicted secreted proteins Evidence at protein level HPA001220 Approved Approved Vesicles Renal cancer:1.79e-4 (unfavourable) Tissue enriched Tissue enhanced cerebral cortex: 18.0;duodenum: 23.2;small intestine: 27.0 kidney: 10.1 Cell line enhanced A549: 25.1;EFO-21: 13.7 +YWHAH YWHA1 ENSG00000128245 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta 22 31944461-31957603 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB025918 Uncertain Liver cancer:1.59e-5 (unfavourable) Expressed in all Tissue enriched 7 cerebral cortex: 896.7 lung: 137.7 Expressed in all +RFPL1 RNF78 ENSG00000128250 Ret finger protein like 1 22 29438583-29442455 Predicted intracellular proteins Evidence at transcript level HPA048320, HPA072380 Approved Nuclear speckles
Plasma membrane Not detected Tissue enriched 8 cerebral cortex: 27.8 adrenal gland: 3.6 Cell line enhanced HDLM-2: 6.6;HMC-1: 2.3;Karpas-707: 2.0;SH-SY5Y: 3.5;THP-1: 2.2 +RFPL2 RNF79 ENSG00000128253 Ret finger protein like 2 22 32190435-32203477 Predicted intracellular proteins Evidence at transcript level HPA048320, HPA072380 Approved Nuclear speckles
Plasma membrane Prostate cancer:4.16e-4 (favourable) Tissue enriched Tissue enriched 7 prostate: 5.8 cerebral cortex: 0.8 Not detected +GNAZ ENSG00000128266 G protein subunit alpha z 22 23070361-23125037 Predicted intracellular proteins Evidence at protein level HPA003011 Enhanced Approved Vesicles Endometrial cancer:4.85e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 49.7 seminal vesicle: 23.0 Cell line enhanced SCLC-21H: 44.4;SH-SY5Y: 24.7 +MGAT3 GNT-III ENSG00000128268 Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 22 39457344-39492194 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017598 Approved Renal cancer:5.04e-8 (unfavourable) Mixed Tissue enhanced cerebral cortex: 38.6 small intestine: 32.5 Cell line enhanced BEWO: 65.1;HMC-1: 51.2;U-266/70: 57.7 +ADORA2A ADORA2, RDC8 ENSG00000128271 Adenosine A2a receptor 22 24417879-24442360 Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB001943, HPA065566, HPA075997 Enhanced Supported Not detected Tissue enhanced bone marrow: 24.6;lymph node: 22.7 appendix: 17.8 Cell line enhanced Karpas-707: 36.8;SK-BR-3: 55.0;U-266/70: 38.8;U-266/84: 50.0;U-698: 37.2 +ATF4 CREB-2, TAXREB67, TXREB ENSG00000128272 Activating transcription factor 4 22 39519695-39522685 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB011596 Approved Supported Microtubule organizing center
Cytosol Renal cancer:9.77e-5 (unfavourable), Liver cancer:4.07e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 530.2 Expressed in all +A4GALT A14GALT, Gb3S, P(k), P1 ENSG00000128274 Alpha 1,4-galactosyltransferase 22 42692121-42721298 Enzymes, Predicted membrane proteins Evidence at protein level HPA001141, HPA076542 Supported Mitochondria Cervical cancer:2.48e-4 (favourable) Expressed in all Mixed seminal vesicle: 30.5 Mixed +RFPL3 ENSG00000128276 Ret finger protein like 3 22 32354885-32361161 Predicted intracellular proteins Evidence at protein level HPA048320, HPA072380 Approved Nuclear speckles
Plasma membrane Not detected Tissue enriched 13 testis: 3.6 prostate: 0.2 Not detected +CDC42EP1 Borg5, CEP1, MSE55 ENSG00000128283 CDC42 effector protein 1 22 37560447-37569405 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006379 Approved Supported Plasma membrane
Actin filaments Expressed in all Expressed in all stomach: 106.6 Mixed +APOL3 APOLIII, CG12-1 ENSG00000128284 Apolipoprotein L3 22 36140330-36166177 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036228 Approved Nuclear bodies
Mitochondria Renal cancer:1.23e-5 (unfavourable), Breast cancer:6.82e-4 (favourable) Expressed in all Mixed spleen: 64.0 Cell line enhanced ASC TERT1: 38.5;Karpas-707: 42.5 +MCHR1 GPR24, MCH1R, SLC1 ENSG00000128285 Melanin concentrating hormone receptor 1 22 40678750-40682814 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:1.49e-6 (unfavourable) Group enriched Tissue enhanced cerebral cortex: 8.6 ovary: 2.1 Cell line enhanced NTERA-2: 1.2;RH-30: 1.6;T-47d: 1.3;U-87 MG: 1.5 +TPST2 TANGO13B ENSG00000128294 Tyrosylprotein sulfotransferase 2 22 26521983-26596717 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021054 Approved Renal cancer:2.34e-6 (unfavourable), Endometrial cancer:8.08e-5 (favourable) Expressed in all Expressed in all epididymis: 135.8 Expressed in all +BAIAP2L2 FLJ22582, pinkbar ENSG00000128298 BAI1 associated protein 2 like 2 22 38084889-38110670 Predicted intracellular proteins Evidence at protein level HPA003043 Approved Expressed in all Tissue enhanced duodenum: 107.2;small intestine: 97.5 gallbladder: 27.4 Cell line enhanced RPTEC TERT1: 22.3;SK-MEL-30: 29.5;WM-115: 29.0 +MPST MST, TST2, TUM1 ENSG00000128309 Mercaptopyruvate sulfurtransferase 22 37019635-37029822 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001240 Enhanced Approved Mitochondria
Cytosol Urothelial cancer:5.89e-4 (favourable) Expressed in all Mixed duodenum: 108.8 Expressed in all +GALR3 ENSG00000128310 Galanin receptor 3 22 37823382-37825495 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected cerebral cortex,testis: 0.2 Not detected +TST RDS ENSG00000128311 Thiosulfate sulfurtransferase 22 37010859-37020183 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003044, HPA003643, CAB009546 Enhanced Supported Mitochondria Renal cancer:7.59e-6 (favourable), Urothelial cancer:1.04e-4 (favourable) Expressed in all Expressed in all colon: 143.5 Mixed +APOL5 APOLV ENSG00000128313 Apolipoprotein L5 22 35717872-35729483 Plasma proteins, Predicted intracellular proteins Evidence at transcript level HPA040968 Uncertain Tissue enriched Not detected skeletal muscle,testis: 0.5 Cell line enriched 12 U-698: 1.2 +IGLL1 14.1, CD179B, IGL5, IGLL, IGVPB ENSG00000128322 Immunoglobulin lambda like polypeptide 1 22 23573125-23580308 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051134, HPA071406 Enhanced Approved Endoplasmic reticulum Tissue enhanced Group enriched 18 bone marrow: 44.2;testis: 15.8 tonsil: 1.6 Cell line enriched 39 REH: 687.9 +APOL2 APOL-II ENSG00000128335 Apolipoprotein L2 22 36226203-36239954 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001078 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:1.22e-7 (unfavourable), Urothelial cancer:5.06e-6 (favourable) Expressed in all Expressed in all gallbladder: 64.8 Expressed in all +RAC2 EN-7 ENSG00000128340 Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 22 37225261-37244448 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB022946, HPA047820 Approved Renal cancer:1.06e-6 (unfavourable), Breast cancer:1.03e-5 (favourable) Expressed in all Expressed in all lymph node: 443.7 Cell line enhanced HL-60: 579.7;HMC-1: 1246.3;U-87 MG: 600.7 +LIF CDF, DIA, HILDA ENSG00000128342 Leukemia inhibitory factor 22 30240447-30246851 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018844, CAB025985 Approved Enhanced Cytosol Renal cancer:6.78e-8 (unfavourable), Cervical cancer:9.01e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 75.6 urinary bladder: 42.0 Cell line enhanced hTEC/SVTERT24-B: 111.9;U-138 MG: 121.7;U-251 MG: 77.3;U-87 MG: 95.4 +C22orf23 EVG1, FLJ32787, LOC84645 ENSG00000128346 Chromosome 22 open reading frame 23 22 37943050-37953669 Predicted intracellular proteins Evidence at protein level HPA000650 Approved Nucleus Mixed Tissue enhanced testis: 145.1 skin: 31.0 Cell line enhanced U-87 MG: 46.8 +APOBEC3A ARP3, PHRBN ENSG00000128383 Apolipoprotein B mRNA editing enzyme catalytic subunit 3A 22 38952741-38992778 Predicted intracellular proteins Evidence at protein level HPA043237, HPA056980, HPA066719 Approved Uncertain Nucleoplasm Tissue enhanced Tissue enhanced appendix: 29.8;bone marrow: 59.0 spleen: 19.5 Not detected +APOBEC3F ARP8, BK150C2.4.MRNA, KA6 ENSG00000128394 Apolipoprotein B mRNA editing enzyme catalytic subunit 3F 22 39040604-39053910 Predicted intracellular proteins Evidence at protein level HPA073637 Uncertain Nucleoplasm
Cytosol Urothelial cancer:8.28e-4 (favourable) Expressed in all Mixed lymph node: 18.5 Mixed +RIBC2 C22orf11, DKFZp566F0546, FLJ25720 ENSG00000128408 RIB43A domain with coiled-coils 2 22 45413691-45432496 Predicted intracellular proteins Evidence at transcript level HPA003210 Uncertain Cervical cancer:7.08e-8 (favourable) Mixed Group enriched 8 fallopian tube: 15.9;testis: 37.3 parathyroid gland: 3.1 Cell line enhanced SiHa: 13.9 +KRT17 PCHC1 ENSG00000128422 Keratin 17 17 41619437-41624842 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000029, HPA000452, HPA000453, HPA000539, HPA045062 Enhanced Enhanced Intermediate filaments Breast cancer:4.44e-4 (favourable), Renal cancer:5.74e-4 (unfavourable) Expressed in all Tissue enhanced breast: 222.3;seminal vesicle: 226.0;urinary bladder: 322.8 prostate: 115.6 Group enriched 6 hTCEpi: 14378.7;SiHa: 8960.6 +EMC4 FLJ90746, MGC24415, PIG17, TMEM85 ENSG00000128463 ER membrane protein complex subunit 4 15 34224999-34230156 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026868, HPA053440 Approved Approved Cell Junctions
Focal adhesion sites Expressed in all Expressed in all epididymis: 122.1 Expressed in all +RNF112 BFP, ZNF179 ENSG00000128482 Ring finger protein 112 17 19411125-19417276 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA015970 Approved Approved Nuclear speckles Tissue enriched Tissue enhanced cerebral cortex: 33.0 prostate: 11.0 Cell line enhanced SCLC-21H: 7.1;SH-SY5Y: 11.1;U-87 MG: 33.6 +SPECC1 CYTSB, FLJ36955, HCMOGT-1, NSP ENSG00000128487 Sperm antigen with calponin homology and coiled-coil domains 1 17 20009344-20319026 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021421, HPA021430 Enhanced Lung cancer:1.06e-5 (unfavourable) Expressed in all Expressed in all testis: 67.2 Cell line enhanced SiHa: 107.9 +CPA4 CPA3 ENSG00000128510 Carboxypeptidase A4 7 130293134-130324180 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021030 Uncertain Approved Nucleoplasm
Centrosome
Cytosol Urothelial cancer:1.31e-4 (unfavourable) Tissue enhanced Tissue enriched 7 skin: 67.8 esophagus: 10.0 Cell line enhanced LHCN-M2: 238.0;U-2 OS: 159.5;U-87 MG: 268.2 +DOCK4 FLJ34238, KIAA0716 ENSG00000128512 Dedicator of cytokinesis 4 7 111726110-112206411 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA071516 Approved Nucleoli
Golgi apparatus
Plasma membrane
Cytosol Expressed in all Tissue enhanced cerebral cortex: 31.9 lung: 27.7 Cell line enhanced hTEC/SVTERT24-B: 42.1;HUVEC TERT2: 67.4;TIME: 57.4 +POT1 DKFZp586D211, hPot1 ENSG00000128513 Protection of telomeres 1 7 124822386-124929983 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA068538 Supported Nucleus Expressed in all Mixed thyroid gland: 21.6 Expressed in all +TAS2R16 T2R16 ENSG00000128519 Taste 2 receptor member 16 7 122994704-122995700 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +ATP6V1F ATP6S14, VATF, Vma7 ENSG00000128524 ATPase H+ transporting V1 subunit F 7 128862826-128865844 Predicted intracellular proteins, Transporters Evidence at protein level CAB009529, HPA048700, HPA062011 Enhanced Renal cancer:2.49e-5 (favourable), Liver cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 288.0 Expressed in all +LSM8 YJR022W ENSG00000128534 LSM8 homolog, U6 small nuclear RNA associated 7 118184032-118192824 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020116 Uncertain Approved Nucleoplasm
Vesicles Renal cancer:7.46e-6 (unfavourable), Endometrial cancer:9.85e-4 (unfavourable) Expressed in all Expressed in all lymph node: 52.4 Expressed in all +CDHR3 CDH28, FLJ23834, FLJ44366 ENSG00000128536 Cadherin related family member 3 7 105876796-106033773 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011218 Uncertain Approved Nucleoli fibrillar center Mixed Tissue enriched 8 fallopian tube: 147.1 lung: 19.1 Cell line enhanced AF22: 4.9;Daudi: 4.7;WM-115: 4.3 +PRKRIP1 C114, FLJ13902, KRBOX3 ENSG00000128563 PRKR interacting protein 1 (IL11 inducible) 7 102363872-102426676 Predicted intracellular proteins Evidence at protein level HPA051146 Uncertain Supported Actin filaments
Cytosol Urothelial cancer:1.94e-4 (favourable), Colorectal cancer:3.65e-4 (unfavourable), Renal cancer:4.39e-4 (unfavourable) Expressed in all Expressed in all testis: 34.7 Expressed in all +VGF SCG7, SgVII ENSG00000128564 VGF nerve growth factor inducible 7 101162509-101165593 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA055177, HPA072505 Enhanced Supported Golgi apparatus
Vesicles Endometrial cancer:4.25e-4 (unfavourable), Glioma:4.43e-4 (unfavourable) Tissue enriched Tissue enriched 22 cerebral cortex: 46.1 adipose tissue: 2.0 Group enriched 11 SH-SY5Y: 182.3;SK-MEL-30: 372.7;U-2 OS: 87.3;WM-115: 139.3 +PODXL Gp200, PC, PCLP ENSG00000128567 Podocalyxin like 7 131500262-131558217 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220 Enhanced Approved Vesicles
Plasma membrane
Microtubule organizing center Renal cancer:2.89e-4 (favourable) Expressed in all Mixed fallopian tube: 29.6 Cell line enhanced fHDF/TERT166: 106.7;NTERA-2: 181.6;TIME: 168.8 +FOXP2 CAGH44, SPCH1, TNRC10 ENSG00000128573 Forkhead box P2 7 114086327-114693772 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000382, HPA000383, HPA001679 Enhanced Enhanced Nucleoplasm Mixed Mixed endometrium: 13.7 Cell line enhanced AF22: 20.9;RH-30: 37.7 +STRIP2 FAM40B, FAR11B, KIAA1170 ENSG00000128578 Striatin interacting protein 2 7 129434433-129488399 Predicted intracellular proteins Evidence at protein level HPA019657 Uncertain Supported Cytosol Stomach cancer:5.41e-4 (favourable), Lung cancer:6.78e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 13.9;testis: 23.5 skeletal muscle: 9.7 Mixed +IFT22 DKFZp761N0823, FLJ13225, FLJ14117, RABL5 ENSG00000128581 Intraflagellar transport 22 7 101313367-101321823 Predicted intracellular proteins Evidence at protein level HPA042930 Approved Approved Microtubules
Cytosol Expressed in all Expressed in all testis: 139.6 Expressed in all +MKLN1 TWA2 ENSG00000128585 Muskelin 1 7 131110096-131496636 Predicted intracellular proteins Evidence at protein level HPA022817, HPA041810 Approved Approved Vesicles
Plasma membrane
Cytosol Expressed in all Expressed in all prostate: 26.0 Expressed in all +DNAJB9 MDG1 ENSG00000128590 DnaJ heat shock protein family (Hsp40) member B9 7 108569568-108574850 Predicted secreted proteins Evidence at protein level HPA040967, HPA041553 Supported Approved Endoplasmic reticulum
Cytosol Expressed in all Expressed in all thyroid gland: 113.5 Expressed in all +FLNC ABP-280, ABPL, FLN2 ENSG00000128591 Filamin C 7 128830377-128859274 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA006135 Enhanced Supported Plasma membrane
Cytosol Lung cancer:2.17e-5 (unfavourable), Urothelial cancer:3.73e-5 (unfavourable), Glioma:2.14e-4 (unfavourable), Renal cancer:5.69e-4 (unfavourable) Expressed in all Tissue enhanced skeletal muscle: 384.7 smooth muscle: 160.7 Cell line enhanced BJ: 331.0;hTEC/SVTERT24-B: 190.2;U-2 OS: 169.5 +LRRC4 NAG14 ENSG00000128594 Leucine rich repeat containing 4 7 128027071-128032107 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051100 Approved Golgi apparatus Renal cancer:6.98e-4 (favourable), Endometrial cancer:8.19e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 52.8 parathyroid gland: 13.1 Group enriched 9 AF22: 16.3;NTERA-2: 36.7;REH: 32.0;SCLC-21H: 22.0;SH-SY5Y: 12.3 +CALU ENSG00000128595 Calumenin 7 128739292-128771807 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006018 Supported Supported Endoplasmic reticulum Renal cancer:1.30e-11 (unfavourable), Urothelial cancer:4.60e-5 (unfavourable), Liver cancer:1.80e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 444.9 Expressed in all +CCDC136 DKFZP434G156, KIAA1793, NAG6 ENSG00000128596 Coiled-coil domain containing 136 7 128790757-128822132 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010647, HPA071015 Enhanced Approved Nucleoli Mixed Tissue enriched 7 testis: 308.5 cerebral cortex: 44.2 Cell line enhanced U-87 MG: 29.4;U-937: 36.3 +SMO FZD11, SMOH ENSG00000128602 Smoothened, frizzled class receptor 7 129188872-129213545 Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011446 Approved Expressed in all Mixed ovary: 30.4 Cell line enhanced AN3-CA: 84.8;NTERA-2: 69.7 +IRF5 ENSG00000128604 Interferon regulatory factor 5 7 128937612-128950035 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046700 Enhanced Expressed in all Mixed spleen: 23.9 Cell line enhanced HDLM-2: 121.5;RPMI-8226: 65.7;U-937: 50.3 +LRRC17 H_RG318M05.3, P37NB ENSG00000128606 Leucine rich repeat containing 17 7 102912991-102944949 Predicted secreted proteins Evidence at protein level HPA030139 Approved Nucleoplasm
Nuclear speckles
Plasma membrane Renal cancer:4.12e-6 (unfavourable), Urothelial cancer:6.30e-4 (unfavourable) Mixed Tissue enhanced ovary: 99.1 gallbladder: 46.8 Group enriched 5 LHCN-M2: 1100.6;RH-30: 248.7 +KLHDC10 KIAA0265, slim ENSG00000128607 Kelch domain containing 10 7 130070510-130135720 Predicted intracellular proteins Evidence at protein level HPA020119 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 69.5 Expressed in all +NDUFA5 B13, CI-13kB, CI-13KD-B, NUFM, UQOR13 ENSG00000128609 NADH:ubiquinone oxidoreductase subunit A5 7 123536997-123558255 Predicted intracellular proteins Evidence at protein level HPA043175 Supported Renal cancer:3.99e-9 (favourable), Breast cancer:8.47e-5 (favourable) Expressed in all Expressed in all thyroid gland: 250.6 Expressed in all +FEZF1 ZNF312B ENSG00000128610 FEZ family zinc finger 1 7 122301394-122310691 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA064639, HPA073693 Approved Supported Nucleus
Cytosol Mixed Tissue enriched 44 testis: 7.0 adipose tissue,cerebral cortex: 0.1 Group enriched 10 NTERA-2: 161.5;SCLC-21H: 82.6 +OPN1SW BCP, BOP, CBT ENSG00000128617 Opsin 1, short wave sensitive 7 128772491-128775790 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA013562, HPA014083 Enhanced Renal cancer:2.26e-8 (unfavourable), Stomach cancer:5.98e-8 (unfavourable), Liver cancer:8.50e-5 (unfavourable), Urothelial cancer:9.33e-4 (unfavourable) Expressed in all Mixed heart muscle: 6.7 Cell line enhanced U-87 MG: 64.7 +MRPS12 RPMS12, RPS12, RPSM12 ENSG00000128626 Mitochondrial ribosomal protein S12 19 38930548-38933162 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046775, HPA050633 Uncertain Expressed in all Expressed in all duodenum: 12.0 Expressed in all +MYO1B myr1 ENSG00000128641 Myosin IB 2 191245185-191425389 Predicted intracellular proteins Evidence at protein level HPA013607, HPA060144 Approved Enhanced Plasma membrane Renal cancer:2.36e-5 (unfavourable) Expressed in all Mixed liver: 130.2 Cell line enhanced hTERT-HME1: 276.9 +HOXD1 HOX4, HOX4G ENSG00000128645 Homeobox D1 2 176188579-176190907 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA040062, HPA056900 Supported Nucleoplasm Tissue enhanced Tissue enhanced epididymis: 8.7;fallopian tube: 7.3 lung: 4.5 Cell line enhanced EFO-21: 5.9;RPTEC TERT1: 15.3;RT4: 12.7;SCLC-21H: 6.3 +HOXD3 HOX1D, HOX4, HOX4A ENSG00000128652 Homeobox D3 2 176136612-176173102 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051831, HPA063671 Enhanced Nucleoplasm
Nuclear bodies Tissue enhanced Tissue enriched 6 epididymis: 46.7 fallopian tube: 8.0 Cell line enhanced EFO-21: 7.4;HSkMC: 6.6;RPTEC TERT1: 7.3;SCLC-21H: 16.3;SH-SY5Y: 9.8 +MTX2 ENSG00000128654 Metaxin 2 2 176269395-176338025 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031550, HPA031551, HPA031552 Approved Approved Supported Nucleoli
Mitochondria Endometrial cancer:5.06e-4 (unfavourable) Expressed in all Expressed in all testis: 116.5 Mixed +PDE11A ENSG00000128655 Phosphodiesterase 11A 2 177623252-178108339 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA034560 Approved Tissue enhanced Tissue enhanced parathyroid gland: 10.5;prostate: 8.8 testis: 6.4 Cell line enhanced fHDF/TERT166: 2.2;Hep G2: 2.0 +CHN1 ARHGAP2, CHN, DURS2, n-chimerin, RhoGAP2 ENSG00000128656 Chimerin 1 2 174799363-175005369 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036111 Approved Cytosol Renal cancer:5.07e-4 (unfavourable) Expressed in all Group enriched 7 cerebral cortex: 639.0;parathyroid gland: 133.3 placenta: 56.0 Cell line enhanced BJ hTERT+: 172.5 +GAD1 GAD ENSG00000128683 Glutamate decarboxylase 1 2 170813213-170861151 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004415, HPA031949, HPA058412, CAB078176 Enhanced Supported Approved Vesicles Cervical cancer:7.31e-4 (favourable), Endometrial cancer:8.61e-4 (favourable) Tissue enhanced Tissue enriched 6 cerebral cortex: 75.3 parathyroid gland: 11.8 Cell line enhanced HEL: 55.7 +OSGEPL1 OSGEPL, Qri7 ENSG00000128694 O-sialoglycoprotein endopeptidase like 1 2 189746660-189763227 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030693 Uncertain Enhanced Mitochondria Ovarian cancer:3.19e-4 (favourable), Liver cancer:3.71e-4 (unfavourable) Expressed in all Mixed testis: 12.2 Expressed in all +ORMDL1 ENSG00000128699 ORMDL sphingolipid biosynthesis regulator 1 2 189770323-189784371 Predicted membrane proteins Evidence at protein level HPA065643 Supported Endoplasmic reticulum Renal cancer:5.84e-9 (unfavourable), Urothelial cancer:1.49e-5 (favourable), Ovarian cancer:3.04e-5 (favourable) Expressed in all Expressed in all epididymis: 155.0 Expressed in all +HAT1 KAT1 ENSG00000128708 Histone acetyltransferase 1 2 171922448-171983682 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036788, CAB037191 Enhanced Enhanced Nucleoplasm Liver cancer:5.72e-5 (unfavourable) Expressed in all Expressed in all lymph node: 56.3 Expressed in all +HOXD9 HOX4, HOX4C ENSG00000128709 Homeobox D9 2 176122720-176124937 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA068683 Supported Nucleus
Nucleoli Liver cancer:1.08e-5 (unfavourable), Colorectal cancer:8.25e-4 (unfavourable), Head and neck cancer:9.58e-4 (favourable) Expressed in all Tissue enhanced endometrium: 45.4 smooth muscle: 23.7 Cell line enhanced HEK 293: 14.8;RPTEC TERT1: 14.2;SH-SY5Y: 23.1;TIME: 13.8 +HOXD10 HOX4, HOX4D ENSG00000128710 Homeobox D10 2 176108790-176119942 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA065871 Approved Nucleoplasm
Cytosol
Cytoplasmic bodies Renal cancer:1.92e-6 (unfavourable) Mixed Tissue enhanced endometrium: 48.3;smooth muscle: 25.2 kidney: 12.7 Cell line enhanced HEK 293: 36.4;RPTEC TERT1: 21.3;SCLC-21H: 12.9;SiHa: 17.8;U-251 MG: 11.0 +HOXD11 HOX4, HOX4F ENSG00000128713 Homeobox D11 2 176104216-176109754 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055155 Approved Nucleoplasm Mixed Tissue enhanced endometrium: 4.2 seminal vesicle: 1.3 Cell line enhanced HEK 293: 18.4;SCLC-21H: 7.0;U-251 MG: 3.8 +HOXD13 HOX4I, SPD ENSG00000128714 Homeobox D13 2 176092891-176095938 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA064064 Supported Nucleus Colorectal cancer:6.95e-5 (unfavourable) Mixed Group enriched 8 cervix, uterine: 7.9;colon: 4.9;prostate: 16.9;rectum: 9.5;seminal vesicle: 24.5 urinary bladder: 1.5 Cell line enhanced HAP1: 20.6;HEK 293: 52.3;HL-60: 52.4;NB-4: 24.7;SCLC-21H: 19.3 +HERC2 D15F37S1, jdf2, p528 ENSG00000128731 HECT and RLD domain containing E3 ubiquitin protein ligase 2 15 28111040-28322152 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017188, HPA048389 Approved Approved Vesicles Renal cancer:1.41e-7 (favourable) Expressed in all Mixed parathyroid gland: 12.1 Cell line enhanced HEL: 48.6 +SNRPN HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN ENSG00000128739 Small nuclear ribonucleoprotein polypeptide N 15 24823637-24978723 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003482, HPA067842 Approved Supported Nucleoplasm Renal cancer:8.93e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 515.1 Cell line enhanced NTERA-2: 762.8 +PSMG2 CLAST3, HCCA3, HsT1707, MDS003, MGC15092, PAC2, TNFSF5IP1 ENSG00000128789 Proteasome assembly chaperone 2 18 12658043-12725740 Predicted intracellular proteins Evidence at protein level HPA041517, HPA046741 Uncertain Approved Nucleus
Nuclear bodies Ovarian cancer:3.09e-4 (favourable) Expressed in all Expressed in all testis: 172.4 Expressed in all +TWSG1 TSG ENSG00000128791 Twisted gastrulation BMP signaling modulator 1 18 9334767-9402420 Predicted secreted proteins Evidence at protein level HPA014898 Uncertain Supported Centrosome
Cytosol Expressed in all Expressed in all smooth muscle: 116.3 Expressed in all +ARHGAP22 RhoGAP2 ENSG00000128805 Rho GTPase activating protein 22 10 48446034-48656265 Predicted intracellular proteins Evidence at protein level CAB020696, HPA040391, HPA064439 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:2.16e-8 (unfavourable) Mixed Mixed cerebral cortex: 8.0 Cell line enhanced LHCN-M2: 53.6;TIME: 56.1;U-87 MG: 81.1 +WDFY4 C10orf64, Em:AC060234.3, FLJ45748, KIAA1607 ENSG00000128815 WDFY family member 4 10 48684876-48982956 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040634 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced lymph node: 33.0;spleen: 23.8 tonsil: 22.1 Cell line enhanced Daudi: 43.5;HDLM-2: 52.1;HL-60: 17.1;U-698: 17.8;U-937: 19.6 +EIF2AK4 GCN2, KIAA1338 ENSG00000128829 Eukaryotic translation initiation factor 2 alpha kinase 4 15 39934146-40035591 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA011811 Approved Approved Cytosol Expressed in all Expressed in all endometrium: 54.3 Expressed in all +MYO5C MGC74969 ENSG00000128833 Myosin VC 15 52192322-52295798 Predicted intracellular proteins Evidence at protein level CAB020790, HPA032115, HPA032116 Enhanced Supported Nucleus
Cytosol Renal cancer:2.47e-5 (favourable), Endometrial cancer:5.18e-5 (favourable), Stomach cancer:5.82e-4 (favourable) Expressed in all Mixed parathyroid gland: 38.6 Cell line enhanced MCF7: 35.3;SK-BR-3: 25.4;T-47d: 38.5 +CGNL1 FLJ14957, JACOP, KIAA1749, PCING ENSG00000128849 Cingulin like 1 15 57375967-57550727 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB013500, HPA056911, HPA069214 Enhanced Approved Cell Junctions Renal cancer:1.37e-6 (favourable), Endometrial cancer:3.55e-4 (favourable), Liver cancer:5.58e-4 (favourable) Expressed in all Mixed kidney: 73.1 Cell line enhanced AF22: 12.9;HUVEC TERT2: 43.8;TIME: 26.5 +TMOD2 NTMOD ENSG00000128872 Tropomodulin 2 15 51751561-51816368 Predicted intracellular proteins Evidence at protein level HPA041365 Enhanced Approved Nucleus
Nucleoli fibrillar center Pancreatic cancer:4.53e-4 (favourable) Tissue enhanced Tissue enriched 9 cerebral cortex: 111.0 seminal vesicle: 11.7 Cell line enhanced SCLC-21H: 43.4 +TTBK2 KIAA0847, SCA11 ENSG00000128881 Tau tubulin kinase 2 15 42738734-42920809 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018113, HPA049866 Approved Uncertain Intermediate filaments Mixed Tissue enhanced testis: 61.5 cerebral cortex: 16.6 Mixed +ELL3 FLJ22637 ENSG00000128886 Elongation factor for RNA polymerase II 3 15 43772600-43777543 Predicted intracellular proteins Evidence at protein level HPA028938 Approved Supported Nucleoplasm
Nucleoli Mixed Tissue enhanced testis: 9.9 lymph node: 4.3 Cell line enhanced Daudi: 5.3;SCLC-21H: 3.8;U-698: 12.4 +C15orf57 CCDC32, MGC20481 ENSG00000128891 Chromosome 15 open reading frame 57 15 40528683-40565057 Predicted intracellular proteins Evidence at protein level HPA041688 Uncertain Approved Nuclear speckles
Vesicles Expressed in all Expressed in all thyroid gland: 35.2 Expressed in all +INO80 hINO80, Ino80, INO80A, INOC1, KIAA1259 ENSG00000128908 INO80 complex subunit 15 40978880-41116354 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041417, HPA041484 Enhanced Nucleoplasm
Nuclear bodies Renal cancer:6.30e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 18.2 Expressed in all +ICE2 BRCC1, FLJ11896, NARG2 ENSG00000128915 Interactor of little elongation complex ELL subunit 2 15 60419609-60479160 Predicted intracellular proteins Evidence at protein level HPA040058 Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 54.0 Expressed in all +DLL4 ENSG00000128917 Delta like canonical Notch ligand 4 15 40929340-40939072 Disease related genes, Predicted membrane proteins Evidence at protein level HPA023392 Uncertain Cervical cancer:3.97e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 28.6 lung: 16.4 Group enriched 14 BJ hTERT+: 48.7;HUVEC TERT2: 13.2;SCLC-21H: 37.4 +ALDH1A2 RALDH2 ENSG00000128918 Aldehyde dehydrogenase 1 family member A2 15 57953424-58497866 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010022 Approved Mixed Tissue enhanced endometrium: 118.1;fallopian tube: 108.9 testis: 96.9 Group enriched 6 AN3-CA: 352.0;HEK 293: 116.8;K-562: 305.3;MOLT-4: 330.5 +MINDY2 FAM63B, KIAA1164 ENSG00000128923 MINDY lysine 48 deubiquitinase 2 15 58771192-58861900 Enzymes, Predicted intracellular proteins Evidence at protein level HPA051103, HPA063669 Approved Enhanced Nucleoplasm Renal cancer:3.00e-8 (favourable) Expressed in all Mixed thyroid gland: 16.3 Expressed in all +IVD ACAD2 ENSG00000128928 Isovaleryl-CoA dehydrogenase 15 40405795-40435947 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041391, HPA044250 Enhanced Enhanced Nucleoplasm
Mitochondria Renal cancer:2.91e-9 (favourable), Liver cancer:1.95e-5 (favourable) Expressed in all Expressed in all thyroid gland: 151.7 Mixed +KNSTRN C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1 ENSG00000128944 Kinetochore localized astrin/SPAG5 binding protein 15 40382721-40394246 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042027 Enhanced Supported Microtubules
Mitotic spindle
Cytosol Renal cancer:7.88e-9 (unfavourable), Pancreatic cancer:3.43e-5 (unfavourable) Expressed in all Tissue enhanced testis: 113.9 thyroid gland: 64.1 Expressed in all +DUT dUTPase ENSG00000128951 Deoxyuridine triphosphatase 15 48331011-48343373 Enzymes, Predicted intracellular proteins Evidence at protein level HPA054422, HPA060360 Enhanced Supported Nucleoplasm Expressed in all Expressed in all lymph node: 114.3 Expressed in all +CHAC1 MGC4504 ENSG00000128965 ChaC glutathione specific gamma-glutamylcyclotransferase 1 15 40952962-40956519 Predicted intracellular proteins Evidence at protein level HPA042708, HPA043505 Approved Renal cancer:2.23e-7 (unfavourable) Expressed in all Tissue enhanced esophagus: 25.5 pancreas: 14.5 Cell line enhanced BJ hTERT+: 88.7;HHSteC: 67.5;hTCEpi: 94.1;SK-MEL-30: 73.8 +CLN6 FLJ20561, HsT18960, nclf ENSG00000128973 Ceroid-lipofuscinosis, neuronal 6, late infantile, variant 15 68206992-68257211 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066046, HPA074162 Approved Approved Vesicles Renal cancer:4.87e-4 (favourable) Expressed in all Expressed in all appendix: 19.8 Expressed in all +ARPP19 ARPP-16, ARPP-19, ARPP16, ENSAL ENSG00000128989 CAMP regulated phosphoprotein 19 15 52547045-52569883 Predicted intracellular proteins Evidence at protein level HPA056851 Approved Renal cancer:1.72e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 510.5 Expressed in all +VPS13C FLJ10381, FLJ20136, KIAA1421 ENSG00000129003 Vacuolar protein sorting 13 homolog C 15 61852389-62060473 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043507 Uncertain Approved Microtubules Expressed in all Expressed in all parathyroid gland: 27.4 Expressed in all +CALML4 MGC4809, NY-BR-20 ENSG00000129007 Calmodulin like 4 15 68190705-68206110 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA051109 Enhanced Approved Nucleoplasm
Golgi apparatus
Cytosol Mixed Tissue enhanced duodenum: 79.8;small intestine: 74.4 colon: 58.5 Mixed +ISLR HsT17563 ENSG00000129009 Immunoglobulin superfamily containing leucine rich repeat 15 74173671-74176872 Predicted secreted proteins Evidence at protein level HPA040326, HPA050811 Approved Approved Golgi apparatus
Plasma membrane Renal cancer:4.89e-8 (unfavourable) Expressed in all Mixed endometrium: 198.8 Cell line enhanced ASC diff: 85.5;ASC TERT1: 46.5;fHDF/TERT166: 227.9;RPMI-8226: 63.5 +THAP10 ENSG00000129028 THAP domain containing 10 15 70881342-70892785 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041416 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.05e-5 (favourable) Expressed in all Mixed cerebral cortex: 10.0 Cell line enhanced U-2197: 36.6 +LOXL1 LOL, LOXL ENSG00000129038 Lysyl oxidase like 1 15 73925989-73952137 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA042111, HPA063583 Approved Approved Endoplasmic reticulum Glioma:1.33e-4 (unfavourable) Expressed in all Mixed seminal vesicle: 16.8 Cell line enhanced BJ hTERT+: 61.2 +ACKR4 CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1 ENSG00000129048 Atypical chemokine receptor 4 3 132597237-132618967 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA054926 Approved Vesicles
Mitochondria Mixed Mixed duodenum: 19.1 Cell line enriched 6 BJ hTERT+: 281.6 +ANAPC13 APC13, DKFZP566D193, SWM1 ENSG00000129055 Anaphase promoting complex subunit 13 3 134477706-134486716 Predicted intracellular proteins Evidence at protein level HPA046114 Uncertain Approved Mitochondria
Cytosol Renal cancer:2.66e-7 (favourable), Cervical cancer:1.66e-4 (favourable), Liver cancer:1.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 155.1 Expressed in all +MBD4 MED1 ENSG00000129071 Methyl-CpG binding domain 4, DNA glycosylase 3 129430944-129440179 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA002031 Supported Supported Nuclear speckles Renal cancer:2.73e-6 (unfavourable), Pancreatic cancer:2.18e-4 (unfavourable), Prostate cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all lymph node: 76.6 Expressed in all +COPB1 COPB ENSG00000129083 Coatomer protein complex subunit beta 1 11 14443440-14500027 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012338, HPA043954, HPA064403 Supported Enhanced Golgi apparatus
Vesicles
Cytosol Liver cancer:5.63e-7 (unfavourable), Head and neck cancer:6.91e-4 (unfavourable), Pancreatic cancer:8.04e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 132.5 Expressed in all +PSMA1 HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30 ENSG00000129084 Proteasome subunit alpha 1 11 14504874-14643635 Enzymes, Predicted intracellular proteins Evidence at protein level CAB033765, HPA037646, HPA043891 Supported Enhanced Nucleoplasm Renal cancer:4.03e-11 (unfavourable), Liver cancer:3.79e-5 (unfavourable) Expressed in all Expressed in all placenta: 120.9 Expressed in all +SUMF2 DKFZp566I1024 ENSG00000129103 Sulfatase modifying factor 2 7 56064002-56080670 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA024040, CAB025743, HPA074892 Enhanced Uncertain Vesicles
Plasma membrane Cervical cancer:6.58e-6 (unfavourable), Endometrial cancer:3.96e-4 (favourable), Urothelial cancer:7.71e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 160.7 Expressed in all +PALLD CGI-151, KIAA0992, SIH002 ENSG00000129116 Palladin, cytoskeletal associated protein 4 168497066-168928457 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035905, CAB070159 Enhanced Supported Plasma membrane
Actin filaments
Cytosol Urothelial cancer:3.28e-4 (unfavourable) Expressed in all Mixed endometrium: 444.9 Cell line enhanced LHCN-M2: 240.0 +SPCS3 FLJ22649, PRO3567, SPC22/23, SPC3, YLR066W ENSG00000129128 Signal peptidase complex subunit 3 4 176319964-176332245 Predicted intracellular proteins Evidence at protein level HPA053180 Approved Endometrial cancer:8.89e-6 (favourable), Pancreatic cancer:1.87e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 104.1 Expressed in all +BBOX1 BBH, BBOX, G-BBH, gamma-BBH ENSG00000129151 Gamma-butyrobetaine hydroxylase 1 11 27040725-27127809 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007600, HPA027823 Enhanced Approved Renal cancer:1.45e-5 (favourable), Endometrial cancer:6.65e-4 (unfavourable) Group enriched Tissue enriched 7 kidney: 473.0 liver: 66.1 Cell line enhanced hTCEpi: 9.6;RPTEC TERT1: 6.3 +MYOD1 bHLHc1, MYF3, MYOD, PUM ENSG00000129152 Myogenic differentiation 1 11 17719568-17722131 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051362 Supported Nucleoplasm
Nuclear bodies
Cytosol Tissue enhanced Tissue enriched 10 skeletal muscle: 9.0 prostate: 0.9 Cell line enriched 17 RH-30: 447.0 +SERGEF DelGEF, Gnefr ENSG00000129158 Secretion regulating guanine nucleotide exchange factor 11 17788048-18013162 Predicted intracellular proteins Evidence at protein level HPA037811, HPA037812, HPA074086 Supported Enhanced Nucleoplasm
Vesicles
Cytosol Glioma:7.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 52.9 Expressed in all +KCNC1 Kv3.1 ENSG00000129159 Potassium voltage-gated channel subfamily C member 1 11 17734774-17856804 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA047634, HPA048249 Enhanced Approved Nucleus
Nuclear membrane
Vesicles
Cytosol Tissue enhanced Tissue enriched 8 cerebral cortex: 18.6 testis: 2.2 Cell line enhanced RH-30: 3.6;SCLC-21H: 4.2;SH-SY5Y: 2.3 +TPH1 TPH, TPRH ENSG00000129167 Tryptophan hydroxylase 1 11 18017564-18042426 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB010767, HPA022483 Enhanced Uncertain Cytosol Mixed Group enriched 6 colon: 8.8;duodenum: 10.2;rectum: 21.0;small intestine: 12.6;stomach: 15.5 prostate: 2.4 Mixed +CSRP3 CLP, CMD1M, MLP ENSG00000129170 Cysteine and glycine rich protein 3 11 19182030-19210573 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042581 Enhanced Tissue enriched Group enriched 25 heart muscle: 1501.4;skeletal muscle: 467.9 prostate: 40.1 Not detected +E2F8 FLJ23311 ENSG00000129173 E2F transcription factor 8 11 19224063-19241620 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA064882 Supported Nucleus
Nucleoli
Cytosol Mixed Mixed bone marrow: 9.2 Mixed +DCTD ENSG00000129187 DCMP deaminase 4 182890060-182917936 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035894 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.81e-4 (favourable) Expressed in all Expressed in all thyroid gland: 167.0 Expressed in all +SOX15 SOX20, SOX26, SOX27 ENSG00000129194 SRY-box 15 17 7588178-7590170 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067196, HPA074049 Enhanced Supported Nucleus
Nucleoli
Golgi apparatus
Vesicles Tissue enhanced Tissue enhanced skin: 40.5 esophagus: 17.5 Group enriched 8 A-431: 108.6;HaCaT: 120.2;HBEC3-KT: 39.0;hTCEpi: 38.2 +FAM64A CATS, FLJ10156, FLJ10491, RCS1 ENSG00000129195 Family with sequence similarity 64 member A 17 6444415-6451469 Predicted intracellular proteins Evidence at protein level HPA043783, HPA049934 Uncertain Enhanced Nucleus Mixed Mixed spleen: 6.2 Cell line enhanced AF22: 158.0 +RPAIN hRIP, MGC4189, RIP ENSG00000129197 RPA interacting protein 17 5419641-5432876 Predicted intracellular proteins Evidence at protein level HPA023924, HPA031526 Approved Approved Nucleus
Nucleoli fibrillar center Prostate cancer:4.41e-5 (unfavourable), Pancreatic cancer:5.20e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 26.7 Expressed in all +USP6 HRP1, Tre-2, TRE17, Tre2, TRESMCR ENSG00000129204 Ubiquitin specific peptidase 6 17 5116438-5175034 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046969 Uncertain Vesicles Tissue enriched Group enriched 5 ovary: 3.5;skeletal muscle: 7.5;testis: 17.1 smooth muscle: 1.8 Mixed +SHBG ABP, MGC126834, MGC138391, TEBG ENSG00000129214 Sex hormone binding globulin 17 7613946-7633383 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enhanced liver: 33.0;testis: 13.7 small intestine: 7.4 Cell line enhanced ASC diff: 3.0;HSkMC: 3.1 +PLD2 ENSG00000129219 Phospholipase D2 17 4807096-4823434 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA013397 Approved Expressed in all Expressed in all esophagus: 42.5 Mixed +AIPL1 LCA4 ENSG00000129221 Aryl hydrocarbon receptor interacting protein like 1 17 6393693-6435199 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026578 Supported Uncertain Nucleoplasm
Cytosol Tissue enriched Not detected testis: 0.8 Cell line enhanced HaCaT: 1.3 +CD68 DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1 ENSG00000129226 CD68 molecule 17 7579467-7582113 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000051, CAB000066, HPA048982, CAB072861, CAB072862 Enhanced Supported Golgi apparatus
Vesicles Renal cancer:1.14e-5 (unfavourable) Mixed Expressed in all lung: 532.4 Expressed in all +TXNDC17 MGC14353, TRP14, TXNL5 ENSG00000129235 Thioredoxin domain containing 17 17 6640758-6644541 Predicted intracellular proteins Evidence at protein level HPA022931 Approved Renal cancer:1.15e-5 (unfavourable) Expressed in all Expressed in all esophagus: 70.0 Expressed in all +ATP1B2 AMOG ENSG00000129244 ATPase Na+/K+ transporting subunit beta 2 17 7646627-7657768 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010698 Enhanced Pancreatic cancer:1.05e-4 (favourable), Renal cancer:4.17e-4 (unfavourable) Tissue enriched Tissue enriched 9 cerebral cortex: 339.2 ovary: 36.7 Cell line enhanced AF22: 9.7;HAP1: 3.1;K-562: 4.2 +FXR2 FMR1L2 ENSG00000129245 FMR1 autosomal homolog 2 17 7591230-7614871 Predicted intracellular proteins Evidence at protein level CAB011205, HPA022997 Supported Supported Cytosol Pancreatic cancer:3.49e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 44.4 Mixed +KIF1C SAX2, SPAX2, SPG58 ENSG00000129250 Kinesin family member 1C 17 4997948-5028401 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024602, HPA045020 Approved Renal cancer:2.26e-9 (favourable) Expressed in all Expressed in all skeletal muscle: 193.6 Expressed in all +MPDU1 CDGIf, Lec35, PQLC5, SL15 ENSG00000129255 Mannose-P-dolichol utilization defect 1 17 7583529-7592789 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014845 Uncertain Supported Endoplasmic reticulum
Mitochondria Expressed in all Expressed in all rectum: 67.3 Expressed in all +PHF20L1 CGI-72, FLJ13649, FLJ21615, MGC64923, TDRD20B ENSG00000129292 PHD finger protein 20-like 1 8 132775358-132848807 Predicted intracellular proteins Evidence at protein level HPA025060, HPA028417 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all thyroid gland: 38.1 Expressed in all +LRRC6 CILD19, LRTP, TSLRP ENSG00000129295 Leucine rich repeat containing 6 8 132571953-132675617 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028058 Approved Thyroid cancer:5.98e-4 (unfavourable) Mixed Tissue enhanced fallopian tube: 31.3;testis: 46.9 kidney: 12.6 Cell line enhanced RPTEC TERT1: 12.0 +CCNT1 CCNT, CYCT1, HIVE1 ENSG00000129315 Cyclin T1 12 48688458-48716998 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004892, CAB009016 Supported Enhanced Nucleoplasm Expressed in all Expressed in all testis: 20.1 Expressed in all +PUS7L DKFZP434G1415 ENSG00000129317 Pseudouridylate synthase 7 like 12 43718993-43758817 Predicted intracellular proteins Evidence at protein level HPA056203, HPA058750 Uncertain Supported Nuclear speckles Expressed in all Mixed parathyroid gland: 9.8 Expressed in all +KRI1 FLJ12949 ENSG00000129347 KRI1 homolog 19 10553078-10566037 Predicted intracellular proteins Evidence at protein level HPA043110, HPA043574 Approved Enhanced Nucleoli Renal cancer:4.89e-10 (unfavourable), Liver cancer:1.21e-4 (unfavourable), Colorectal cancer:9.37e-4 (unfavourable) Expressed in all Expressed in all appendix: 26.6 Expressed in all +ILF3 DRBP76, MPHOSPH4, MPP4, NF90, NFAR-1 ENSG00000129351 Interleukin enhancer binding factor 3 19 10654261-10692417 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001897 Supported Supported Nucleoplasm
Nucleoli
Mitochondria Melanoma:1.57e-4 (unfavourable), Renal cancer:9.65e-4 (unfavourable) Expressed in all Expressed in all testis: 149.4 Expressed in all +SLC44A2 CTL2 ENSG00000129353 Solute carrier family 44 member 2 19 10602457-10644559 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA003228, HPA070799 Approved Approved Vesicles
Cell Junctions Renal cancer:1.71e-5 (favourable), Pancreatic cancer:6.01e-4 (unfavourable) Expressed in all Expressed in all placenta: 226.1 Mixed +AP1M2 AP1-mu2, HSMU1B, mu2 ENSG00000129354 Adaptor related protein complex 1 mu 2 subunit 19 10572671-10587315 Predicted intracellular proteins Evidence at protein level HPA054999 Supported Vesicles Renal cancer:3.73e-6 (favourable), Endometrial cancer:2.07e-4 (favourable) Mixed Mixed thyroid gland: 98.3 Cell line enhanced Hep G2: 212.3;MCF7: 206.6;U-2 OS: 174.7 +CDKN2D INK4D, p19 ENSG00000129355 Cyclin dependent kinase inhibitor 2D 19 10566462-10569059 Predicted intracellular proteins Evidence at protein level CAB011201, HPA043546 Enhanced Supported Nucleoplasm
Cytosol Cervical cancer:1.02e-4 (favourable), Liver cancer:4.82e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 181.1 cerebral cortex: 61.3 Expressed in all +MTUS1 ATBP, ATIP1, DKFZp586D1519, FLJ14295, ICIS, KIAA1288, MP44, MTSG1 ENSG00000129422 Microtubule associated tumor suppressor 1 8 17643795-17800917 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067903, HPA069795 Enhanced Nucleoli
Microtubules Colorectal cancer:1.05e-4 (favourable), Renal cancer:2.76e-4 (favourable) Expressed in all Mixed parathyroid gland: 128.1 Cell line enhanced A549: 104.4;AN3-CA: 92.7;HUVEC TERT2: 247.3 +KLK14 KLK-L6 ENSG00000129437 Kallikrein related peptidase 14 19 51077495-51084245 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB026228 Uncertain Tissue enhanced Tissue enriched 5 skin: 10.4 breast: 2.0 Cell line enhanced HaCaT: 8.7;U-266/84: 3.7 +SIGLEC9 CD329 ENSG00000129450 Sialic acid binding Ig like lectin 9 19 51124908-51136651 Predicted membrane proteins Evidence at protein level HPA010682 Uncertain Renal cancer:6.17e-5 (unfavourable) Mixed Tissue enhanced appendix: 24.7;spleen: 23.5 lung: 12.2 Group enriched 7 Karpas-707: 16.8;RPMI-8226: 11.4 +KLK10 NES1, PRSSL1 ENSG00000129451 Kallikrein related peptidase 10 19 51012739-51020175 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at protein level HPA017195 Uncertain Plasma membrane
Cytosol Pancreatic cancer:6.46e-5 (unfavourable), Breast cancer:8.32e-4 (favourable) Mixed Tissue enhanced esophagus: 138.2;skin: 52.7 tonsil: 45.8 Group enriched 5 CAPAN-2: 200.9;HaCaT: 307.2 +KLK8 HNP, neuropsin, ovasin, PRSS19, TADG14 ENSG00000129455 Kallikrein related peptidase 8 19 50996007-51002711 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB019393, HPA035761 Enhanced Approved Vesicles Pancreatic cancer:1.10e-4 (unfavourable), Endometrial cancer:2.31e-4 (unfavourable), Lung cancer:5.72e-4 (unfavourable), Urothelial cancer:6.17e-4 (unfavourable) Tissue enhanced Group enriched 6 esophagus: 77.9;fallopian tube: 20.9;skin: 96.8 breast: 11.0 Group enriched 7 A-431: 76.9;CAPAN-2: 98.5;HaCaT: 73.3 +NGDN C14orf120, CANu1, DKFZP564O092, LCP5, lpd-2, NGD ENSG00000129460 Neuroguidin 14 23469688-23509862 Predicted intracellular proteins Evidence at protein level HPA000944 Approved Approved Nucleus
Nucleoli
Mitochondria Expressed in all Expressed in all endometrium: 55.2 Expressed in all +RIPK3 RIP3 ENSG00000129465 Receptor interacting serine/threonine kinase 3 14 24336021-24340045 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055087 Uncertain Mixed Mixed small intestine: 25.1 Cell line enhanced CAPAN-2: 11.3;HDLM-2: 6.9;SK-BR-3: 15.6 +ADCY4 AC4 ENSG00000129467 Adenylate cyclase 4 14 24318349-24335093 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB005070, HPA048344 Approved Renal cancer:7.01e-4 (unfavourable), Endometrial cancer:8.20e-4 (favourable) Expressed in all Tissue enhanced placenta: 21.1 lung: 11.6 Group enriched 6 HUVEC TERT2: 7.8;TIME: 3.1 +RAB2B FLJ14824 ENSG00000129472 RAB2B, member RAS oncogene family 14 21459020-21476973 Predicted intracellular proteins Evidence at protein level HPA050292 Uncertain Expressed in all Expressed in all prostate: 19.1 Expressed in all +BCL2L2 BCL-W, KIAA0271, PPP1R51 ENSG00000129473 BCL2 like 2 14 23298790-23311759 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB040539 Approved Renal cancer:1.99e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 88.8 Expressed in all +AJUBA JUB, MGC15563 ENSG00000129474 Ajuba LIM protein 14 22971174-22982642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA006171 Approved Approved Nucleus
Golgi apparatus Pancreatic cancer:5.67e-4 (unfavourable) Expressed in all Tissue enhanced skin: 73.7 placenta: 28.0 Mixed +DTD2 C14orf126, MGC9912 ENSG00000129480 D-tyrosyl-tRNA deacylase 2 (putative) 14 31446036-31457510 Predicted intracellular proteins Evidence at protein level HPA001117 Approved Approved Vesicles Urothelial cancer:5.74e-6 (unfavourable), Head and neck cancer:9.33e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 10.8 Expressed in all +PARP2 ADPRTL2 ENSG00000129484 Poly(ADP-ribose) polymerase 2 14 20343582-20357905 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA052003 Approved Approved Nucleus
Nucleoli Liver cancer:6.48e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 46.3 Expressed in all +HEATR5A C14orf125, DKFZP434I1735 ENSG00000129493 HEAT repeat containing 5A 14 31291791-31420582 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA049539 Uncertain Renal cancer:1.11e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 18.2 Expressed in all +FOXA1 HNF3A ENSG00000129514 Forkhead box A1 14 37589984-37596059 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB011595, HPA050505 Enhanced Supported Nucleoplasm
Nucleoli fibrillar center Urothelial cancer:1.00e-4 (favourable) Tissue enhanced Tissue enhanced prostate: 146.0 breast: 36.3 Cell line enhanced MCF7: 98.8;PC-3: 81.2;RT4: 94.9;SK-BR-3: 88.5;T-47d: 157.4 +SNX6 ENSG00000129515 Sorting nexin 6 14 34561094-34630183 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049374 Approved Supported Endosomes
Lysosomes Liver cancer:1.25e-4 (unfavourable), Pancreatic cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 220.7 Expressed in all +EAPP BM036, C14orf11, FLJ20578 ENSG00000129518 E2F associated phosphoprotein 14 34515929-34539711 Predicted intracellular proteins Evidence at protein level HPA002916 Approved Approved Nucleus
Golgi apparatus
Cytosol Renal cancer:2.23e-6 (favourable), Thyroid cancer:2.96e-4 (favourable), Lung cancer:9.34e-4 (favourable) Expressed in all Expressed in all thyroid gland: 75.0 Expressed in all +EGLN3 HIFPH3, PHD3 ENSG00000129521 Egl-9 family hypoxia inducible factor 3 14 33924231-34462774 Enzymes, Predicted intracellular proteins Evidence at protein level HPA064895 Approved Cytosol Liver cancer:2.14e-5 (unfavourable), Renal cancer:2.50e-4 (unfavourable) Expressed in all Tissue enhanced skin: 98.0 heart muscle: 62.0 Cell line enhanced RH-30: 43.2;RT4: 97.7 +MIS18BP1 C14orf106, FLJ11186, KIAA1903, KNL2, M18BP1 ENSG00000129534 MIS18 binding protein 1 14 45203190-45253540 Predicted intracellular proteins Evidence at protein level HPA006504 Approved Approved Nucleoli
Cytosol Liver cancer:3.83e-4 (unfavourable) Expressed in all Mixed lymph node: 25.9 Expressed in all +NRL D14S46E, NRL-MAF, RP27 ENSG00000129535 Neural retina leucine zipper 14 24080107-24115014 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026066, HPA064599 Supported Supported Nucleoplasm
Cytosol Mixed Mixed parathyroid gland: 4.6 Mixed +RNASE1 RAC1, RNS1 ENSG00000129538 Ribonuclease A family member 1, pancreatic 14 20801228-20803278 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001140 Supported Approved Nucleoplasm
Vesicles Expressed in all Expressed in all pancreas: 1946.8 Group enriched 6 HUVEC TERT2: 239.6;RT4: 91.0;TIME: 122.8 +NEDD8 Nedd-8 ENSG00000129559 Neural precursor cell expressed, developmentally down-regulated 8 14 24216852-24232454 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004082, HPA027583, HPA060254 Uncertain Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 559.0 Expressed in all +DAD1 OST2 ENSG00000129562 Defender against cell death 1 14 22564905-22589269 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA028882 Uncertain Approved Cytosol Liver cancer:7.73e-4 (unfavourable) Expressed in all Expressed in all epididymis: 516.1 Expressed in all +TEP1 p240, TLP1, TP1, TROVE1, VAULT2 ENSG00000129566 Telomerase associated protein 1 14 20365667-20413429 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029206 Supported Nucleoplasm
Vesicles Endometrial cancer:9.58e-4 (favourable) Expressed in all Mixed parathyroid gland: 46.9 Expressed in all +EPB41L4A NBL4 ENSG00000129595 Erythrocyte membrane protein band 4.1 like 4A 5 112142441-112419316 Predicted intracellular proteins Evidence at protein level HPA036580 Uncertain Approved Nucleoplasm
Plasma membrane Renal cancer:3.65e-5 (favourable) Mixed Expressed in all parathyroid gland: 25.6 Cell line enhanced EFO-21: 28.6;HeLa: 23.8 +CDO1 ENSG00000129596 Cysteine dioxygenase type 1 5 115804733-115816954 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036573, HPA057503 Enhanced Uncertain Nucleoplasm Liver cancer:1.91e-5 (favourable) Group enriched Tissue enhanced epididymis: 137.5;liver: 209.9 adipose tissue: 104.0 Cell line enhanced AF22: 38.7;ASC diff: 32.4;HAP1: 14.4;NTERA-2: 14.5 +REEP5 C5orf18, D5S346, DP1, TB2, Yip2e ENSG00000129625 Receptor accessory protein 5 5 112876379-112922539 Predicted membrane proteins Evidence at protein level HPA003895, HPA069960 Approved Approved Endoplasmic reticulum Endometrial cancer:5.23e-6 (favourable), Renal cancer:2.05e-5 (favourable) Expressed in all Expressed in all thyroid gland: 343.0 Expressed in all +ITFG1 CDA08, LNKN-1, TIP ENSG00000129636 Integrin alpha FG-GAP repeat containing 1 16 47154387-47464149 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015590, HPA019728 Approved Approved Intermediate filaments
Aggresome Renal cancer:1.95e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 110.1 Expressed in all +QRICH2 DKFZP434P0316 ENSG00000129646 Glutamine rich 2 17 76274049-76307998 Predicted intracellular proteins Evidence at protein level HPA052219 Enhanced Approved Nucleoplasm
Nuclear membrane
Vesicles Expressed in all Tissue enriched 11 testis: 22.2 thyroid gland: 1.9 Mixed +FOXJ1 FKHL13, HFH-4, HFH4 ENSG00000129654 Forkhead box J1 17 76136333-76141299 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005714 Enhanced Renal cancer:2.03e-5 (unfavourable), Breast cancer:9.39e-4 (favourable) Tissue enhanced Tissue enriched 8 fallopian tube: 83.6 lung: 10.3 Group enriched 10 BEWO: 28.2;CAPAN-2: 21.8 +SEC14L1 PRELID4A, SEC14L ENSG00000129657 SEC14 like lipid binding 1 17 77086716-77217101 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021463, HPA028703 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all placenta: 119.5 Expressed in all +RHBDF2 FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG ENSG00000129667 Rhomboid 5 homolog 2 17 76470891-76501790 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018080 Uncertain Renal cancer:3.96e-11 (unfavourable) Expressed in all Expressed in all appendix: 49.4 Mixed +AANAT SNAT ENSG00000129673 Aralkylamine N-acetyltransferase 17 76453351-76470117 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054321 Supported Cytosol Not detected Tissue enhanced testis: 4.5 appendix: 2.2 Cell line enhanced A549: 2.2;SCLC-21H: 3.5;U-698: 2.5 +ARHGEF6 alpha-PIX, alphaPIX, Cool-2, Cool2, KIAA0006, MRX46 ENSG00000129675 Rac/Cdc42 guanine nucleotide exchange factor 6 X 136665547-136782088 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003578 Approved Approved Cytosol Expressed in all Mixed placenta: 63.3 Cell line enhanced HL-60: 113.2;HMC-1: 452.5;U-937: 117.5 +MAP7D3 FLJ12649 ENSG00000129680 MAP7 domain containing 3 X 136213220-136256482 Predicted intracellular proteins Evidence at protein level HPA035598, HPA058101 Approved Enhanced Centrosome Urothelial cancer:5.38e-5 (unfavourable), Endometrial cancer:9.00e-5 (unfavourable), Stomach cancer:7.91e-4 (unfavourable) Expressed in all Mixed testis: 30.0 Mixed +FGF13 FGF2, FHF2 ENSG00000129682 Fibroblast growth factor 13 X 138614731-139222777 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA002809 Supported Cytosol Mixed Tissue enhanced parathyroid gland: 108.4 cerebral cortex: 47.9 Cell line enhanced AF22: 42.4;HAP1: 40.9;U-2197: 64.4;WM-115: 37.0 +ASH2L ASH2, ASH2L1, ASH2L2, Bre2 ENSG00000129691 ASH2 like histone lysine methyltransferase complex subunit 8 38105242-38144076 Predicted intracellular proteins Evidence at protein level HPA042289 Approved Supported Nucleoplasm
Plasma membrane Renal cancer:4.25e-4 (favourable) Expressed in all Expressed in all testis: 74.9 Expressed in all +TTI2 C8orf41, FLJ23263 ENSG00000129696 TELO2 interacting protein 2 8 33473386-33513601 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023523, HPA029823 Approved Enhanced Centrosome Expressed in all Mixed testis: 22.1 Expressed in all +ART1 ART2, CD296 ENSG00000129744 ADP-ribosyltransferase 1 11 3645128-3664416 CD markers, Enzymes, Predicted membrane proteins Evidence at transcript level HPA051148 Uncertain Not detected Tissue enriched 21 skeletal muscle: 16.4 esophagus: 0.7 Not detected +CHRNA10 ENSG00000129749 Cholinergic receptor nicotinic alpha 10 subunit 11 3665587-3671384 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Mixed Tissue enriched 21 skeletal muscle: 16.6 appendix,lung: 0.7 Mixed +CDKN1C BWCR, BWS, KIP2, P57 ENSG00000129757 Cyclin dependent kinase inhibitor 1C 11 2883213-2885881 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA002924 Enhanced Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Tissue enhanced placenta: 202.5 adipose tissue: 62.5 Cell line enhanced HeLa: 21.7;SH-SY5Y: 31.6;SiHa: 21.0 +SGO1 NY-BR-85, SGOL1 ENSG00000129810 Shugoshin 1 3 20160593-20186292 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035501, HPA069857 Enhanced Supported Nucleoplasm
Cytosol Mixed Tissue enhanced testis: 13.2 lymph node: 8.1 Mixed +RPS4Y1 MGC119100, MGC5070, RPS4Y, S4 ENSG00000129824 Ribosomal protein S4, Y-linked 1 Y 2841486-2932000 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA000857 Approved Mixed Mixed prostate: 403.7 Cell line enhanced U-698: 1166.0 +VCY1B BPY1B ENSG00000129862 Variable charge, Y-linked 1B Y 14056217-14056958 Predicted intracellular proteins Evidence at protein level HPA044996, HPA049357 Supported Not detected Tissue enriched 85 testis: 27.1 placenta: 0.3 Cell line enriched 6 U-266/70: 1.0 +VCY BPY1, VCY1, VCY1A ENSG00000129864 Variable charge, Y-linked Y 13985772-13986513 Predicted intracellular proteins Evidence at protein level HPA044996, HPA049357 Supported Not detected Tissue enriched 85 testis: 27.1 placenta: 0.3 Cell line enriched 6 U-266/70: 1.0 +CDY2B CDY ENSG00000129873 Chromodomain Y-linked 2B Y 17877410-17880220 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Not detected testis: 0.2 Not detected +CDH15 CDH14, CDH3 ENSG00000129910 Cadherin 15 16 89171767-89195492 Disease related genes, Predicted membrane proteins Evidence at protein level HPA009139, HPA070961 Enhanced Supported Golgi apparatus
Cytosol Mixed Tissue enriched 11 skeletal muscle: 13.0 placenta: 1.1 Cell line enriched 5 RH-30: 142.1 +KLF16 BTEB4, DRRF, NSLP2 ENSG00000129911 Kruppel like factor 16 19 1852399-1863568 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052481 Approved Supported Nucleus Renal cancer:2.93e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 17.5 Expressed in all +TMEM8A M83, TMEM6, TMEM8 ENSG00000129925 Transmembrane protein 8A 16 370773-387113 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA051281, HPA064673 Approved Supported Nucleoplasm
Cytokinetic bridge Renal cancer:1.29e-5 (favourable) Expressed in all Expressed in all testis: 57.1 Expressed in all +DOHH HLRC1, MGC4293 ENSG00000129932 Deoxyhypusine hydroxylase 19 3490821-3500940 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041953 Approved Approved Nucleus
Cytosol Endometrial cancer:2.24e-4 (favourable), Pancreatic cancer:3.58e-4 (favourable) Expressed in all Mixed duodenum: 17.8 Expressed in all +MAU2 KIAA0892, mau-2, MAU2L, MGC75361, SCC4 ENSG00000129933 MAU2 sister chromatid cohesion factor 19 19320681-19358755 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059897 Supported Nucleoplasm Head and neck cancer:3.90e-5 (favourable) Expressed in all Expressed in all testis: 25.6 Expressed in all +SHC2 SCK, SHCB, SLI ENSG00000129946 SHC adaptor protein 2 19 416583-460996 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA006136 Approved Approved Cytosol Colorectal cancer:4.58e-4 (unfavourable), Pancreatic cancer:8.53e-4 (favourable) Expressed in all Mixed cerebral cortex: 18.7 Cell line enhanced SCLC-21H: 14.8;SH-SY5Y: 12.0 +PLPPR3 FLJ11535, LPPR3, PRG-2, PRG2 ENSG00000129951 Phospholipid phosphatase related 3 19 812488-821977 Enzymes, Predicted membrane proteins Evidence at protein level HPA052293, HPA057034 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced Tissue enhanced bone marrow: 6.1;cerebral cortex: 9.6;fallopian tube: 8.9 testis: 2.1 Cell line enhanced NB-4: 38.6;THP-1: 86.0 +INS-IGF2 ENSG00000129965 INS-IGF2 readthrough 11 2132538-2161209 Predicted secreted proteins Evidence at protein level CAB019430 Enhanced Not detected Tissue enhanced pancreas: 1.6;placenta: 3.3 adrenal gland,endometrium: 0.5 Cell line enhanced SH-SY5Y: 1.3 +ABHD17A C19orf27, FAM108A1, MGC5244 ENSG00000129968 Abhydrolase domain containing 17A 19 1876810-1885547 Predicted intracellular proteins Evidence at protein level HPA043270, HPA047226 Uncertain Approved Vesicles Pancreatic cancer:1.76e-5 (favourable), Endometrial cancer:1.73e-4 (favourable), Head and neck cancer:6.46e-4 (favourable) Expressed in all Mixed cerebral cortex: 31.4 Mixed +LBP BPIFD2 ENSG00000129988 Lipopolysaccharide binding protein 20 38346356-38377023 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA001508, CAB025905 Approved Renal cancer:3.62e-12 (unfavourable), Cervical cancer:5.56e-4 (unfavourable), Stomach cancer:5.76e-4 (unfavourable) Tissue enriched Group enriched 5 adipose tissue: 69.3;liver: 264.7 appendix: 31.3 Group enriched 7 ASC diff: 6.7;HSkMC: 8.5 +SYT5 ENSG00000129990 Synaptotagmin 5 19 55171199-55180441 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA078390 Enhanced Pancreatic cancer:5.54e-4 (favourable), Glioma:8.26e-4 (unfavourable) Mixed Tissue enriched 10 cerebral cortex: 131.4 adrenal gland: 12.7 Cell line enhanced EFO-21: 25.6;HMC-1: 53.1;K-562: 20.2;SCLC-21H: 18.7 +TNNI3 CMD2A, CMH7, TNNC1 ENSG00000129991 Troponin I3, cardiac type 19 55151767-55157773 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009349, HPA046428 Enhanced Approved Vesicles
Cytosol Mixed Tissue enriched 174 heart muscle: 3607.1 breast: 20.7 Cell line enhanced HEK 293: 11.1;HMC-1: 17.7;K-562: 34.7 +CBFA2T3 ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4 ENSG00000129993 CBFA2/RUNX1 translocation partner 3 16 88874858-88977204 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA059931, HPA062423, HPA065890 Approved Enhanced Nucleoplasm Head and neck cancer:3.95e-4 (favourable) Mixed Tissue enhanced spleen: 18.7 lymph node: 10.4 Cell line enhanced HEL: 57.7;K-562: 102.3;MOLT-4: 46.5;REH: 103.4;T-47d: 47.0 +GAMT PIG2, TP53I2 ENSG00000130005 Guanidinoacetate N-methyltransferase 19 1397026-1401570 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051806 Approved Stomach cancer:6.57e-4 (unfavourable) Tissue enriched Group enriched 5 epididymis: 173.0;liver: 158.9;skeletal muscle: 425.6 pancreas: 48.1 Mixed +PUDP DXF68S1E, FAM16AX, GS1, HDHD1, HDHD1A ENSG00000130021 Pseudouridine 5'-phosphatase X 7048920-7148190 Enzymes, Predicted intracellular proteins Evidence at protein level HPA072672 Approved Thyroid cancer:4.80e-4 (favourable), Pancreatic cancer:7.27e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 31.3 Mixed +ERMARD C6orf70, dJ266L20.3, FLJ11152 ENSG00000130023 ER membrane associated RNA degradation 6 169751622-169781584 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041741 Approved Approved Cytosol Expressed in all Expressed in all testis: 33.2 Expressed in all +PHF10 BAF45a, FLJ10975, XAP135 ENSG00000130024 PHD finger protein 10 6 169703905-169725566 Predicted intracellular proteins Evidence at protein level HPA055649 Supported Supported Nucleus Pancreatic cancer:1.12e-5 (favourable), Renal cancer:1.56e-5 (unfavourable), Liver cancer:3.42e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 103.6 Expressed in all +PRRG3 TMG3 ENSG00000130032 Proline rich and Gla domain 3 X 151695124-151705924 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060566 Uncertain Mixed Tissue enhanced cerebral cortex: 8.9 cervix, uterine: 7.5 Cell line enhanced NTERA-2: 1.0 +GALNT8 GALNAC-T8 ENSG00000130035 Polypeptide N-acetylgalactosaminyltransferase 8 12 4720341-4851927 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012638, HPA014418, HPA073461 Approved Approved Vesicles Tissue enhanced Group enriched 7 cerebral cortex: 19.4;colon: 17.6;duodenum: 8.1;rectum: 40.6;small intestine: 18.9;testis: 26.5 appendix: 3.2 Cell line enhanced Karpas-707: 24.5;NTERA-2: 12.1;U-2 OS: 4.6;U-266/84: 7.3 +KCNA5 HK2, HPCN1, Kv1.5 ENSG00000130037 Potassium voltage-gated channel subfamily A member 5 12 5043989-5046788 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA021516, CAB022562 Approved Mixed Tissue enhanced heart muscle: 16.1 esophagus: 5.6 Cell line enriched 20 NTERA-2: 4.3 +CRACR2A EFCAB4B, MGC4266 ENSG00000130038 Calcium release activated channel regulator 2A 12 3606633-3764819 Predicted intracellular proteins Evidence at protein level HPA038686 Enhanced Prostate cancer:2.85e-6 (favourable) Mixed Mixed salivary gland: 15.1 Mixed +NXNL2 C9orf121 ENSG00000130045 Nucleoredoxin-like 2 9 88535101-88584274 Predicted intracellular proteins Evidence at transcript level HPA045526 Uncertain Approved Cytosol Endometrial cancer:3.83e-8 (favourable), Breast cancer:6.53e-4 (favourable), Renal cancer:9.60e-4 (favourable) Group enriched Mixed adipose tissue: 7.7 Cell line enhanced RPTEC TERT1: 7.9 +STARD8 ARHGAP38, KIAA0189 ENSG00000130052 StAR related lipid transfer domain containing 8 X 68647666-68725842 Predicted intracellular proteins Evidence at protein level HPA060788 Uncertain Expressed in all Mixed adipose tissue: 14.9 Cell line enhanced HEL: 14.3;K-562: 18.2 +FAM155B CXorf63, TED, TMEM28 ENSG00000130054 Family with sequence similarity 155 member B X 69505241-69532508 Predicted membrane proteins Evidence at transcript level HPA036093 Uncertain Breast cancer:4.61e-5 (unfavourable), Prostate cancer:1.83e-4 (unfavourable), Renal cancer:6.63e-4 (favourable) Mixed Tissue enhanced heart muscle: 10.8;seminal vesicle: 8.5;thyroid gland: 16.7 cerebral cortex: 2.5 Cell line enhanced AN3-CA: 8.3;HAP1: 20.7;NTERA-2: 27.5;SCLC-21H: 15.3 +GDPD2 FLJ20207, GDE3, OBDPF ENSG00000130055 Glycerophosphodiester phosphodiesterase domain containing 2 X 70423031-70433390 Enzymes, Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced skin: 50.8;spleen: 60.0 small intestine: 20.0 Group enriched 8 AF22: 8.8;NTERA-2: 19.3 +SAT1 SAT, SSAT ENSG00000130066 Spermidine/spermine N1-acetyltransferase 1 X 23783173-23786226 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB047343, HPA055312, CAB069914 Supported Endometrial cancer:2.87e-4 (favourable) Expressed in all Expressed in all thyroid gland: 1269.5 Expressed in all +GNL3L FLJ10613, GNL3B ENSG00000130119 G protein nucleolar 3 like X 54530211-54561071 Predicted intracellular proteins Evidence at protein level HPA036314, HPA036315 Supported Supported Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all thyroid gland: 16.4 Expressed in all +SH3BP4 ENSG00000130147 SH3 domain binding protein 4 2 234951973-235055714 Predicted intracellular proteins Evidence at protein level HPA037533, HPA037534 Uncertain Renal cancer:2.07e-6 (favourable) Expressed in all Mixed breast: 42.6 Mixed +MOSPD2 MGC26706 ENSG00000130150 Motile sperm domain containing 2 X 14873441-14922327 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003334 Uncertain Approved Endoplasmic reticulum Liver cancer:8.91e-4 (unfavourable) Expressed in all Mixed skin: 28.6 Expressed in all +DOCK6 KIAA1395, ZIR1 ENSG00000130158 Dedicator of cytokinesis 6 19 11199295-11262481 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049423, HPA049424 Approved Supported Cytosol Head and neck cancer:9.09e-4 (favourable) Expressed in all Mixed skin: 29.4 Cell line enhanced HUVEC TERT2: 57.1;TIME: 56.1 +ECSIT SITPEC ENSG00000130159 ECSIT signalling integrator 19 11505916-11529174 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042979 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.48e-9 (favourable) Expressed in all Expressed in all heart muscle: 54.2 Expressed in all +LDLR LDLCQ2 ENSG00000130164 Low density lipoprotein receptor 19 11089362-11133816 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA009647, HPA013159 Approved Pancreatic cancer:6.60e-5 (unfavourable), Urothelial cancer:3.43e-4 (unfavourable), Renal cancer:5.92e-4 (unfavourable) Expressed in all Expressed in all lung: 87.6 Expressed in all +ELOF1 ELF1, MGC4549 ENSG00000130165 Elongation factor 1 homolog 19 11551147-11559236 Predicted intracellular proteins Evidence at protein level HPA045606 Uncertain Approved Cytosol Cervical cancer:1.83e-4 (favourable) Expressed in all Expressed in all testis: 163.7 Expressed in all +TSPAN16 TM-8, TM4-B, TM4SF16 ENSG00000130167 Tetraspanin 16 19 11296139-11326996 Predicted membrane proteins Evidence at protein level HPA041579 Approved Not detected Tissue enriched 46 testis: 154.0 bone marrow: 3.3 Not detected +ANGPTL8 C19orf80, RIFL, TD26 ENSG00000130173 Angiopoietin like 8 19 11237450-11241943 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042131 Approved Nucleoplasm
Golgi apparatus Renal cancer:1.84e-6 (unfavourable) Tissue enriched Group enriched 20 adipose tissue: 13.7;liver: 63.8 epididymis: 1.9 Group enriched 28 Hep G2: 24.9;MCF7: 16.3 +PRKCSH G19P1, GIIB, PCLD, PLD1, VASAP-60 ENSG00000130175 Protein kinase C substrate 80K-H 19 11435288-11450968 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB004465, HPA041940, HPA043560 Enhanced Enhanced Endoplasmic reticulum Renal cancer:7.69e-4 (unfavourable) Expressed in all Expressed in all ovary: 237.6 Expressed in all +CNN1 Sm-Calp, SMCC ENSG00000130176 Calponin 1 19 11538717-11550323 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB000007, HPA014263 Enhanced Approved Actin filaments Renal cancer:5.43e-6 (unfavourable) Expressed in all Tissue enhanced seminal vesicle: 2110.1;smooth muscle: 3106.1 endometrium: 1736.7 Cell line enhanced BJ: 76.7;BJ hTERT+ SV40 Large T+: 43.2;BJ hTERT+ SV40 Large T+ RasG12V: 62.2;HBF TERT88: 68.9 +CDC16 ANAPC6, APC6, CUT9 ENSG00000130177 Cell division cycle 16 13 114234887-114272723 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA042826 Approved Expressed in all Expressed in all testis: 83.8 Expressed in all +ZSCAN10 ZNF206 ENSG00000130182 Zinc finger and SCAN domain containing 10 16 3088890-3099317 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enriched Not detected skin: 0.6 Cell line enriched 123 NTERA-2: 56.8 +THEM6 C8orf55, DSCD75 ENSG00000130193 Thioesterase superfamily member 6 8 142727203-142736927 Predicted intracellular proteins Evidence at protein level HPA023255 Uncertain Approved Nuclear speckles
Cytosol Renal cancer:6.66e-7 (favourable), Urothelial cancer:4.49e-4 (favourable) Expressed in all Expressed in all thyroid gland: 18.5 Cell line enhanced RT4: 89.6 +NECTIN2 CD112, HVEB, PRR2, PVRL2, PVRR2 ENSG00000130202 Nectin cell adhesion molecule 2 19 44846175-44889228 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012759, CAB026138, HPA073459 Enhanced Approved Nucleoli fibrillar center
Cell Junctions Expressed in all Expressed in all placenta: 111.4 Mixed +APOE AD2 ENSG00000130203 Apolipoprotein E 19 44905754-44909393 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB008363, HPA065539, HPA068768, CAB069921 Enhanced Approved Vesicles Expressed in all Expressed in all adrenal gland: 1801.1 Cell line enhanced ASC diff: 1276.1;Hep G2: 626.6;HSkMC: 991.4;SK-MEL-30: 1417.0 +TOMM40 C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40 ENSG00000130204 Translocase of outer mitochondrial membrane 40 19 44890569-44903689 Predicted intracellular proteins, Transporters Evidence at protein level HPA036231, HPA036232 Supported Enhanced Mitochondria
Cytosol Expressed in all Expressed in all parathyroid gland: 34.9 Expressed in all +APOC1 ENSG00000130208 Apolipoprotein C1 19 44914247-44919349 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA051518 Supported Liver cancer:1.15e-7 (favourable) Tissue enriched Tissue enriched 7 liver: 7257.2 adrenal gland: 1113.0 Cell line enhanced Hep G2: 389.1;HSkMC: 242.1;SK-MEL-30: 203.2 +GADD45G CR6, DDIT2, GADD45gamma, GRP17 ENSG00000130222 Growth arrest and DNA damage inducible gamma 9 89605013-89606555 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023606 Approved Approved Nucleus Pancreatic cancer:3.80e-5 (favourable), Endometrial cancer:7.06e-4 (favourable) Expressed in all Mixed adrenal gland: 47.2 Cell line enhanced HDLM-2: 108.4;SCLC-21H: 69.0 +LRCH2 KIAA1495 ENSG00000130224 Leucine rich repeats and calponin homology domain containing 2 X 115110616-115234072 Predicted intracellular proteins Evidence at protein level HPA003233 Approved Approved Nucleoli
Plasma membrane Mixed Mixed prostate: 13.8 Cell line enhanced HAP1: 22.2 +DPP6 DPL1, DPPX ENSG00000130226 Dipeptidyl peptidase like 6 7 153887097-154894285 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA050509 Enhanced Supported Tissue enriched Tissue enhanced cerebral cortex: 51.1;endometrium: 27.6 smooth muscle: 15.4 Cell line enriched 9 NTERA-2: 5.5 +XPO7 KIAA0745, RANBP16 ENSG00000130227 Exportin 7 8 21919671-22006585 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA043727, HPA048153 Uncertain Approved Nucleus Colorectal cancer:2.29e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 78.8 Expressed in all +ACE2 ENSG00000130234 Angiotensin I converting enzyme 2 X 15561033-15602148 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA000288, CAB026174 Enhanced Renal cancer:2.12e-5 (favourable), Liver cancer:4.21e-4 (favourable) Tissue enhanced Group enriched 5 duodenum: 181.1;gallbladder: 100.2;kidney: 94.0;small intestine: 261.1;testis: 93.0 heart muscle: 27.9 Cell line enhanced HaCaT: 1.1 +FAM98C FLJ44669 ENSG00000130244 Family with sequence similarity 98 member C 19 38403135-38409088 Predicted intracellular proteins Evidence at protein level HPA040930, HPA041730 Approved Approved Nucleus
Nucleoli
Cytosol Ovarian cancer:8.51e-5 (unfavourable), Urothelial cancer:5.53e-4 (favourable) Expressed in all Mixed small intestine: 15.2 Expressed in all +SAFB2 KIAA0138 ENSG00000130254 Scaffold attachment factor B2 19 5586999-5624046 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050894 Approved Supported Nucleoplasm
Nuclear bodies
Vesicles Urothelial cancer:2.12e-4 (favourable), Pancreatic cancer:2.53e-4 (favourable), Endometrial cancer:7.10e-4 (favourable) Expressed in all Expressed in all ovary: 40.0 Expressed in all +RPL36 DKFZp566B023, L36 ENSG00000130255 Ribosomal protein L36 19 5674947-5691876 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047153 Supported Uncertain Endoplasmic reticulum
Cytosol Renal cancer:2.32e-4 (unfavourable) Expressed in all Expressed in all ovary: 2363.0 Expressed in all +ATP8B3 ATPIK ENSG00000130270 ATPase phospholipid transporting 8B3 19 1782075-1812276 Enzymes, Predicted membrane proteins Evidence at transcript level Renal cancer:4.80e-9 (unfavourable) Mixed Tissue enriched 7 testis: 28.7 bone marrow: 4.0 Cell line enhanced Karpas-707: 16.1;U-266/70: 14.2 +GDF1 ENSG00000130283 Growth differentiation factor 1 19 18868545-18896096 Disease related genes, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 7 cerebral cortex: 12.2 testis: 1.7 Cell line enhanced EFO-21: 2.8;HEK 293: 3.3;NB-4: 3.1;NTERA-2: 2.4;SCLC-21H: 2.4 +NCAN CSPG3 ENSG00000130287 Neurocan 19 19211973-19252233 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036814 Enhanced Uncertain Vesicles
Centrosome Tissue enriched Tissue enriched 101 cerebral cortex: 183.5 testis: 1.8 Cell line enhanced AF22: 1.0;SCLC-21H: 2.7;SH-SY5Y: 1.7 +KIF1A ATSV, C2orf20, SPG30, UNC104 ENSG00000130294 Kinesin family member 1A 2 240713764-240820308 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005442 Approved Microtubule organizing center
Cytosol Endometrial cancer:4.97e-4 (unfavourable) Tissue enhanced Tissue enriched 13 cerebral cortex: 308.3 adrenal gland: 23.0 Cell line enhanced AN3-CA: 79.8;HAP1: 157.5;K-562: 125.1;SCLC-21H: 477.1 +GTPBP3 FLJ14700, GTPBG3, MSS1, MTGP1, THDF1 ENSG00000130299 GTP binding protein 3 (mitochondrial) 19 17334920-17342735 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042158 Approved Supported Mitochondria Renal cancer:1.64e-4 (unfavourable), Liver cancer:1.86e-4 (unfavourable), Prostate cancer:2.81e-4 (unfavourable) Expressed in all Expressed in all skin: 12.3 Expressed in all +PLVAP FELS, gp68, PV-1, PV1 ENSG00000130300 Plasmalemma vesicle associated protein 19 17351448-17377350 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002279 Supported Expressed in all Expressed in all thyroid gland: 329.1 Cell line enriched 31 EFO-21: 506.3 +BST2 CD317, tetherin ENSG00000130303 Bone marrow stromal cell antigen 2 19 17402939-17405648 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA017060 Approved Supported Golgi apparatus
Plasma membrane
Cytosol Renal cancer:3.56e-9 (unfavourable), Testis cancer:4.22e-4 (unfavourable), Breast cancer:6.69e-4 (favourable) Expressed in all Expressed in all ovary: 586.7 Mixed +SLC27A1 ACSVL5, FATP, FATP1, FLJ00336, MGC71751 ENSG00000130304 Solute carrier family 27 member 1 19 17468769-17506168 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA076520 Approved Plasma membrane
Mitochondria
Cytosol Renal cancer:4.70e-4 (favourable) Expressed in all Mixed parathyroid gland: 34.5 Cell line enhanced SK-MEL-30: 36.4 +NSUN5 FLJ10267, NOL1R, NSUN5A, p120(NOL1), WBSCR20, WBSCR20A, Ynl022cL ENSG00000130305 NOP2/Sun RNA methyltransferase family member 5 7 73302517-73308867 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020536, HPA045590, HPA046867 Approved Enhanced Nucleus
Nucleoli Glioma:2.11e-4 (unfavourable), Liver cancer:3.96e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 26.0 Mixed +USHBP1 AIEBP, FLJ38709, MCC2 ENSG00000130307 USH1 protein network component harmonin binding protein 1 19 17249176-17282786 Predicted intracellular proteins Evidence at protein level HPA052471 Uncertain Mixed Mixed placenta: 8.2 Cell line enhanced BEWO: 10.6 +COLGALT1 FLJ22329, GLT25D1 ENSG00000130309 Collagen beta(1-O)galactosyltransferase 1 19 17555594-17583162 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA047821 Approved Approved Vesicles Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.65e-5 (unfavourable), Pancreatic cancer:1.92e-4 (unfavourable), Urothelial cancer:3.83e-4 (unfavourable) Expressed in all Expressed in all placenta: 58.0 Expressed in all +DDA1 C19orf58, MGC2594, PCIA1 ENSG00000130311 DET1 and DDB1 associated 1 19 17309518-17323301 Predicted intracellular proteins Evidence at protein level HPA042134, HPA055272 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all placenta: 11.6 Expressed in all +MRPL34 L34mt, MGC24974, MGC2633 ENSG00000130312 Mitochondrial ribosomal protein L34 19 17292609-17306843 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA049276 Uncertain Approved Nucleoplasm
Nuclear bodies
Vesicles Renal cancer:4.29e-6 (favourable), Pancreatic cancer:4.87e-4 (favourable) Expressed in all Expressed in all kidney: 76.6 Expressed in all +PGLS 6PGL ENSG00000130313 6-phosphogluconolactonase 19 17511629-17521288 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040744, HPA042032 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all fallopian tube: 46.7 Expressed in all +LSM7 YNL147W ENSG00000130332 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated 19 2321517-2328620 Predicted intracellular proteins Evidence at protein level HPA041850 Uncertain Approved Nucleoli fibrillar center Endometrial cancer:4.19e-5 (favourable), Cervical cancer:3.28e-4 (favourable), Urothelial cancer:6.96e-4 (favourable) Expressed in all Expressed in all lymph node: 70.9 Expressed in all +TULP4 KIAA1397, TUSP ENSG00000130338 Tubby like protein 4 6 158232236-158511828 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005445 Approved Expressed in all Mixed cerebral cortex: 12.6 Expressed in all +SNX9 SDP1, SH3PX1, SH3PXD3A ENSG00000130340 Sorting nexin 9 6 157700387-157945077 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031410, HPA057203 Approved Enhanced Plasma membrane
Cytosol Lung cancer:3.77e-4 (unfavourable), Cervical cancer:5.95e-4 (unfavourable), Renal cancer:9.95e-4 (favourable) Expressed in all Expressed in all gallbladder: 68.2 Mixed +RTN4IP1 NIMP ENSG00000130347 Reticulon 4 interacting protein 1 6 106571971-106629487 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036357 Approved Renal cancer:8.55e-6 (favourable), Breast cancer:9.18e-6 (unfavourable) Expressed in all Mixed parathyroid gland: 11.4 Expressed in all +QRSL1 DKFZP564C1278, FLJ10989, FLJ12189, FLJ13447, GatA ENSG00000130348 Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 6 106629578-106668417 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029585, HPA029587 Approved Approved Vesicles
Centrosome Liver cancer:7.97e-5 (unfavourable), Renal cancer:3.83e-4 (favourable) Expressed in all Expressed in all lymph node: 18.6 Expressed in all +C6orf203 HSPC230, PRED31 ENSG00000130349 Chromosome 6 open reading frame 203 6 107028213-107051342 Predicted intracellular proteins Evidence at protein level HPA049535 Approved Urothelial cancer:2.11e-5 (favourable), Renal cancer:4.09e-5 (favourable), Pancreatic cancer:3.29e-4 (favourable) Expressed in all Expressed in all adrenal gland: 47.6 Expressed in all +RSPH3 dJ111C20.1, RSHL2, RSP3 ENSG00000130363 Radial spoke 3 homolog 6 158972871-159000187 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039109, HPA040230 Approved Approved Vesicles
Plasma membrane
Cytosol Renal cancer:2.19e-4 (favourable) Expressed in all Mixed parathyroid gland: 26.4 Mixed +MAS1 ENSG00000130368 MAS1 proto-oncogene, G protein-coupled receptor 6 159906690-159916530 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced cerebral cortex: 1.8 cervix, uterine: 0.7 Cell line enriched 9 HMC-1: 6.7 +ACSBG2 BGR, DKFZp434K1635, PRTD-NY3 ENSG00000130377 Acyl-CoA synthetase bubblegum family member 2 19 6135247-6193094 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043421, HPA051013 Enhanced Uncertain Cytosol Not detected Tissue enriched 716 testis: 294.0 cerebral cortex: 0.4 Not detected +MLLT1 ENL, LTG19, YEATS1 ENSG00000130382 MLLT1, super elongation complex subunit 19 6210379-6279948 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031166 Approved Supported Nucleoplasm Head and neck cancer:6.03e-5 (favourable) Expressed in all Expressed in all placenta: 61.5 Expressed in all +FUT5 FUC-TV ENSG00000130383 Fucosyltransferase 5 19 5865826-5870540 Enzymes, Predicted membrane proteins Evidence at transcript level HPA046966 Uncertain Not detected Not detected bone marrow,testis: 0.3 Not detected +BMP15 GDF9B ENSG00000130385 Bone morphogenetic protein 15 X 50910784-50916607 Disease related genes, Predicted secreted proteins Evidence at protein level Not detected Not detected fallopian tube: 0.3 Not detected +AFDN AF-6, AF6, MLLT4 ENSG00000130396 Afadin, adherens junction formation factor 6 167826922-167972023 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868 Approved Enhanced Nucleoplasm
Plasma membrane
Cell Junctions Breast cancer:7.43e-5 (unfavourable) Expressed in all Expressed in all esophagus: 110.7 Mixed +ACTN4 FSGS1 ENSG00000130402 Actinin alpha 4 19 38647649-38731583 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001873, HPA006035 Supported Approved Nuclear bodies
Cytosol Renal cancer:5.25e-5 (favourable), Pancreatic cancer:5.65e-4 (unfavourable), Lung cancer:8.82e-4 (unfavourable) Expressed in all Expressed in all esophagus: 118.4 Expressed in all +STK33 ENSG00000130413 Serine/threonine kinase 33 11 8391868-8594289 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015742, HPA056855 Uncertain Approved Nucleus
Nucleoli
Cytosol Renal cancer:4.89e-6 (favourable) Mixed Tissue enhanced fallopian tube: 67.1;testis: 93.1 parathyroid gland: 43.4 Cell line enhanced SCLC-21H: 26.8 +NDUFA10 CI-42k ENSG00000130414 NADH:ubiquinone oxidoreductase subunit A10 2 239892450-240025402 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059529, HPA067045, CAB070846 Approved Supported Mitochondria Renal cancer:2.09e-7 (favourable), Melanoma:2.95e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 63.8 Expressed in all +EPO EP ENSG00000130427 Erythropoietin 7 100720800-100723700 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Predicted secreted proteins Evidence at protein level CAB010336 Supported Renal cancer:2.18e-6 (unfavourable), Liver cancer:5.67e-5 (unfavourable) Group enriched Tissue enhanced cervix, uterine: 2.0;endometrium: 1.7;liver: 1.7 prostate: 1.1 Group enriched 6 BEWO: 2.0;Hep G2: 5.5 +ARPC1B ARC41, p40-ARC, p41-ARC ENSG00000130429 Actin related protein 2/3 complex subunit 1B 7 99374249-99394801 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004832 Approved Supported Vesicles
Cytosol Renal cancer:1.62e-6 (unfavourable), Liver cancer:2.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 251.5 Expressed in all +CACNG6 ENSG00000130433 Calcium voltage-gated channel auxiliary subunit gamma 6 19 53992288-54012669 Predicted membrane proteins, Transporters Evidence at transcript level HPA056615 Approved Nucleoli fibrillar center
Cytosol Mixed Group enriched 11 fallopian tube: 18.0;skeletal muscle: 33.9 lung: 2.3 Cell line enhanced A549: 13.3;EFO-21: 23.7;HHSteC: 5.4 +ZSWIM6 KIAA1577 ENSG00000130449 Zinc finger SWIM-type containing 6 5 61332273-61546170 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035938 Uncertain Approved Cytosol Expressed in all Mixed parathyroid gland: 17.0 Mixed +FCHO1 KIAA0290 ENSG00000130475 FCH domain only 1 19 17747718-17788568 Predicted intracellular proteins Evidence at protein level HPA041653, HPA062981 Approved Enhanced Nucleoplasm
Cytosol Mixed Tissue enhanced lymph node: 28.8 spleen: 19.9 Cell line enhanced Daudi: 44.6 +UNC13A KIAA1032, Munc13-1 ENSG00000130477 Unc-13 homolog A 19 17601328-17688365 Predicted intracellular proteins Evidence at protein level HPA041418, HPA077242 Uncertain Uncertain Nuclear membrane
Endoplasmic reticulum
Cytosol Tissue enhanced Tissue enriched 16 cerebral cortex: 53.5 adrenal gland: 3.4 Group enriched 7 HMC-1: 14.3;NTERA-2: 23.7;SCLC-21H: 45.8;SH-SY5Y: 9.8 +MAP1S BPY2IP1, C19orf5, FLJ10669, MAP8, VCY2IP1 ENSG00000130479 Microtubule associated protein 1S 19 17719242-17734516 Predicted intracellular proteins Evidence at protein level HPA050934, HPA054637 Approved Enhanced Cytosol Pancreatic cancer:2.65e-4 (favourable), Liver cancer:5.29e-4 (unfavourable) Expressed in all Expressed in all testis: 29.5 Expressed in all +KLHDC7B MGC16635 ENSG00000130487 Kelch domain containing 7B 22 50548033-50551023 Predicted intracellular proteins Evidence at protein level HPA000518 Uncertain Breast cancer:1.30e-4 (favourable) Tissue enhanced Tissue enhanced parathyroid gland: 12.7 thyroid gland: 3.4 Group enriched 6 HHSteC: 18.6;HMC-1: 87.0 +SCO2 MYP6, SCO1L ENSG00000130489 SCO2, cytochrome c oxidase assembly protein 22 50523568-50525606 Disease related genes, Predicted membrane proteins Evidence at protein level HPA046943, HPA056254 Approved Approved Mitochondria Renal cancer:1.67e-4 (unfavourable) Expressed in all Expressed in all appendix: 47.1 Expressed in all +PXDN D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN ENSG00000130508 Peroxidasin 2 1631887-1744852 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012375 Approved Endometrial cancer:2.75e-4 (unfavourable), Cervical cancer:6.28e-4 (unfavourable), Stomach cancer:6.73e-4 (unfavourable) Expressed in all Tissue enhanced smooth muscle: 87.2 adipose tissue: 66.9 Mixed +SSBP4 ENSG00000130511 Single stranded DNA binding protein 4 19 18418864-18434562 Predicted intracellular proteins Evidence at protein level Renal cancer:2.04e-10 (unfavourable), Pancreatic cancer:1.01e-4 (favourable) Expressed in all Expressed in all spleen: 51.1 Expressed in all +GDF15 MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB ENSG00000130513 Growth differentiation factor 15 19 18374731-18389176 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011191, CAB062554, HPA070957 Enhanced Enhanced Golgi apparatus Expressed in all Tissue enhanced placenta: 122.1;prostate: 74.5 kidney: 41.6 Cell line enhanced BEWO: 401.5;HHSteC: 474.6 +PGPEP1 Pcp, PGP, PGP-I, PGPI ENSG00000130517 Pyroglutamyl-peptidase I 19 18340587-18369950 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035368, HPA055277 Approved Approved Golgi apparatus Renal cancer:3.71e-8 (favourable), Pancreatic cancer:1.71e-4 (favourable), Melanoma:6.80e-4 (favourable) Expressed in all Expressed in all kidney: 29.3 Cell line enhanced HMC-1: 51.6 +KIAA1683 ENSG00000130518 KIAA1683 19 18257097-18274509 Predicted intracellular proteins Evidence at protein level HPA042409 Enhanced Mixed Tissue enriched 6 testis: 34.3 endometrium: 5.3 Cell line enhanced A549: 2.3 +LSM4 YER112W ENSG00000130520 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated 19 18306230-18323274 Predicted intracellular proteins Evidence at protein level HPA040932 Uncertain Approved Vesicles Ovarian cancer:1.34e-4 (favourable), Renal cancer:2.22e-4 (favourable) Expressed in all Expressed in all testis: 102.4 Expressed in all +JUND AP-1 ENSG00000130522 JunD proto-oncogene, AP-1 transcription factor subunit 19 18279760-18281622 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005268, HPA063029 Supported Supported Nucleus Breast cancer:6.15e-5 (favourable) Expressed in all Expressed in all bone marrow: 277.7 Expressed in all +HRC MGC133236 ENSG00000130528 Histidine rich calcium binding protein 19 49151198-49155424 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004833 Enhanced Mixed Group enriched 39 heart muscle: 351.8;skeletal muscle: 155.5 epididymis,prostate: 6.5 Group enriched 6 Hep G2: 3.9;HSkMC: 4.0;K-562: 7.1;THP-1: 9.3;U-266/84: 3.0 +TRPM4 FLJ20041 ENSG00000130529 Transient receptor potential cation channel subfamily M member 4 19 49157741-49211836 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA041169 Enhanced Supported Nucleoplasm
Plasma membrane Renal cancer:2.53e-7 (favourable), Endometrial cancer:2.88e-7 (favourable) Expressed in all Mixed prostate: 29.4 Cell line enhanced RT4: 47.8 +OR11H1 OR22-1 ENSG00000130538 Olfactory receptor family 11 subfamily H member 1 22 15528158-15529139 G-protein coupled receptors, Predicted membrane proteins No evidence HPA047370 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +SULT4A1 hBR-STL-1, SULTX3 ENSG00000130540 Sulfotransferase family 4A member 1 22 43824509-43862503 Predicted intracellular proteins Evidence at protein level HPA003129 Enhanced Tissue enhanced Tissue enriched 35 cerebral cortex: 143.6 adrenal gland: 4.0 Not detected +ZNF557 MGC4054 ENSG00000130544 Zinc finger protein 557 19 7069444-7087968 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003151, HPA029291 Uncertain Approved Nucleus
Intermediate filaments
Cytosol Head and neck cancer:3.67e-6 (favourable), Pancreatic cancer:1.51e-4 (favourable), Lung cancer:2.62e-4 (favourable), Endometrial cancer:5.70e-4 (favourable) Expressed in all Mixed testis: 5.4 Expressed in all +CRB3 MGC17303 ENSG00000130545 Crumbs 3, cell polarity complex component 19 6463777-6467221 Predicted membrane proteins Evidence at protein level HPA013835 Enhanced Supported Cell Junctions Renal cancer:0.00e+0 (favourable), Urothelial cancer:8.06e-5 (favourable), Endometrial cancer:4.54e-4 (favourable) Mixed Mixed duodenum: 37.4 Cell line enhanced A-431: 50.4;BEWO: 34.1;CACO-2: 31.7;HaCaT: 32.6 +OLFM1 AMY, NOE1, NOELIN, OlfA ENSG00000130558 Olfactomedin 1 9 135075422-135121179 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA057444 Approved Nucleus
Nucleoli
Cytosol Cervical cancer:7.14e-4 (favourable), Glioma:9.38e-4 (unfavourable) Expressed in all Tissue enriched 8 cerebral cortex: 729.9 epididymis: 86.4 Cell line enhanced NTERA-2: 108.6;SCLC-21H: 182.9;SiHa: 139.8;T-47d: 189.5;U-2197: 81.2 +CAMSAP1 DKFZp434F195, FLJ31228 ENSG00000130559 Calmodulin regulated spectrin associated protein 1 9 135808487-135907228 Predicted intracellular proteins Evidence at protein level HPA020527, HPA024161 Approved Supported Mitotic spindle
Cytosol Renal cancer:3.09e-5 (favourable) Expressed in all Expressed in all testis: 34.2 Expressed in all +UBAC1 GBDR1, KPC2, UBADC1 ENSG00000130560 UBA domain containing 1 9 135932969-135961380 Predicted intracellular proteins Evidence at protein level HPA005651 Approved Supported Golgi apparatus
Plasma membrane
Cytosol Renal cancer:3.58e-7 (favourable), Cervical cancer:4.34e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 88.7 Expressed in all +SAG ARRESTIN, RP47 ENSG00000130561 S-antigen visual arrestin 2 233307816-233347055 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA004946 Supported Not detected Group enriched 8 epididymis: 1.1;testis: 1.9 endometrium: 0.1 Not detected +ZBTB46 BTBD4, BZEL, FLJ13502, RINZF, ZNF340 ENSG00000130584 Zinc finger and BTB domain containing 46 20 63743666-63831244 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA013997 Uncertain Approved Nucleus Pancreatic cancer:2.17e-4 (favourable) Expressed in all Mixed spleen: 13.3 Mixed +HELZ2 KIAA1769, PDIP1, PRIC285 ENSG00000130589 Helicase with zinc finger 2 20 63558086-63574239 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051267 Uncertain Testis cancer:4.92e-4 (unfavourable) Expressed in all Mixed spleen: 15.2 Cell line enhanced BJ hTERT+ SV40 Large T+: 55.4 +SAMD10 C20orf136 ENSG00000130590 Sterile alpha motif domain containing 10 20 63974113-63980008 Predicted intracellular proteins Evidence at protein level HPA040973 Approved Approved Nucleoplasm Liver cancer:4.60e-4 (unfavourable) Expressed in all Mixed lymph node: 7.6 Mixed +LSP1 WP34 ENSG00000130592 Lymphocyte-specific protein 1 11 1852970-1892267 Predicted intracellular proteins Evidence at protein level CAB017781, HPA019693, HPA071843 Enhanced Supported Plasma membrane Endometrial cancer:2.54e-4 (favourable), Cervical cancer:3.56e-4 (favourable), Glioma:9.00e-4 (unfavourable) Expressed in all Expressed in all spleen: 279.2 Cell line enhanced Daudi: 229.4;HDLM-2: 1037.0;RPMI-8226: 322.1 +TNNT3 AMCD2B, DA2B, DKFZp779M2348, FSSV ENSG00000130595 Troponin T3, fast skeletal type 11 1919562-1938706 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB002451, HPA037810, HPA056909 Enhanced Cervical cancer:7.37e-4 (favourable) Group enriched Tissue enriched 72 skeletal muscle: 9522.9 esophagus: 132.2 Cell line enriched 15 HSkMC: 34.3 +TNNI2 AMCD2B, DA2B, FSSV ENSG00000130598 Troponin I2, fast skeletal type 11 1838989-1841680 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB018697, HPA055938 Enhanced Approved Plasma membrane
Intermediate filaments Group enriched Tissue enriched 38 skeletal muscle: 5537.1 esophagus: 144.6 Cell line enhanced CAPAN-2: 62.9;hTCEpi: 145.7;T-47d: 23.3 +COL5A1 ENSG00000130635 Collagen type V alpha 1 chain 9 134641774-134844843 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030769 Approved Approved Vesicles Renal cancer:2.07e-12 (unfavourable) Expressed in all Mixed cervix, uterine: 157.8 Cell line enhanced BJ: 370.0;fHDF/TERT166: 317.6;SiHa: 305.8 +ATXN10 E46L, FLJ37990, SCA10 ENSG00000130638 Ataxin 10 22 45671798-45845307 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049531 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all cerebral cortex: 133.9 Expressed in all +TUBGCP2 GCP2, SPBC97, Spc97p ENSG00000130640 Tubulin gamma complex associated protein 2 10 133278630-133312337 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037885 Approved Supported Nucleoplasm
Centrosome Expressed in all Expressed in all fallopian tube: 34.3 Expressed in all +CALY CALCYON, DRD1IP, NSG3 ENSG00000130643 Calcyon neuron specific vesicular protein 10 133324072-133336935 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042283 Enhanced Pancreatic cancer:3.54e-4 (favourable) Group enriched Group enriched 13 adrenal gland: 23.5;cerebral cortex: 77.1 testis: 3.8 Not detected +CYP2E1 CYP2E ENSG00000130649 Cytochrome P450 family 2 subfamily E member 1 10 133520406-133561220 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA009128, HPA029564 Enhanced Tissue enriched Tissue enriched 177 liver: 5332.2 tonsil: 30.1 Cell line enhanced HaCaT: 9.7;NB-4: 15.1 +PNPLA7 C9orf111, FLJ31318, FLJ43070, FLJ44279, NTE-R1, NTEL1, RP11-48C7.2 ENSG00000130653 Patatin like phospholipase domain containing 7 9 137459953-137550534 Predicted membrane proteins Evidence at protein level HPA009130 Uncertain Uncertain Microtubule organizing center
Cytosol Pancreatic cancer:2.24e-5 (favourable) Tissue enhanced Mixed prostate: 17.6 Cell line enriched 21 HMC-1: 72.0 +HBZ HBZ-T1, HBZ1 ENSG00000130656 Hemoglobin subunit zeta 16 152687-154503 Predicted intracellular proteins Evidence at protein level HPA071726 Approved Not detected Group enriched 12 bone marrow: 2.3;placenta: 1.0;testis: 3.9 skin: 0.2 Cell line enriched 80 K-562: 2107.5 +PAK4 ENSG00000130669 P21 (RAC1) activated kinase 4 19 39125770-39182816 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB025747, CAB044670, HPA070175, HPA072220 Uncertain Supported Plasma membrane
Cell Junctions Renal cancer:5.29e-5 (favourable), Prostate cancer:9.85e-4 (unfavourable) Expressed in all Expressed in all prostate: 47.8 Expressed in all +MNX1 HB9, HLXB9, HOXHB9, SCRA1 ENSG00000130675 Motor neuron and pancreas homeobox 1 7 156994051-157010651 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071717 Approved Nucleus
Nucleoli
Cytosol Mixed Tissue enhanced duodenum: 7.3;small intestine: 6.7 colon: 3.7 Cell line enhanced AN3-CA: 16.0;EFO-21: 15.3;RPMI-8226: 25.9;SCLC-21H: 22.6 +ZNF337 dJ694B14.1 ENSG00000130684 Zinc finger protein 337 20 25674215-25696841 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044303, HPA064219 Approved Approved Nuclear speckles
Plasma membrane Renal cancer:2.87e-6 (unfavourable) Mixed Expressed in all parathyroid gland: 27.9 Expressed in all +CEP85 CCDC21, DKFZP434L0117 ENSG00000130695 Centrosomal protein 85 1 26234153-26279038 Predicted intracellular proteins Evidence at protein level HPA028252 Approved Supported Nucleoli
Golgi apparatus
Microtubule organizing center
Cytosol Liver cancer:4.39e-6 (unfavourable) Expressed in all Tissue enhanced skeletal muscle: 48.1;testis: 52.4 heart muscle: 17.5 Expressed in all +TAF4 TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135 ENSG00000130699 TATA-box binding protein associated factor 4 20 61953469-62065810 Predicted intracellular proteins Evidence at protein level HPA008599, CAB031484 Supported Enhanced Nucleoplasm Liver cancer:3.31e-4 (unfavourable) Expressed in all Mixed testis: 6.6 Mixed +GATA5 bB379O24.1, GATAS ENSG00000130700 GATA binding protein 5 20 62463497-62475970 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067583 Approved Nucleoplasm
Cytosol Tissue enhanced Tissue enhanced duodenum: 11.4;small intestine: 11.0;testis: 8.7 stomach: 7.5 Cell line enhanced HEL: 2.6;K-562: 4.2;SiHa: 2.1;T-47d: 4.4 +RBBP8NL C20orf151, dJ908M14.3 ENSG00000130701 RBBP8 N-terminal like 20 62410237-62427533 Predicted intracellular proteins Evidence at protein level HPA042627 Uncertain Urothelial cancer:6.91e-4 (favourable) Mixed Tissue enhanced small intestine: 5.2 duodenum: 4.5 Cell line enhanced BEWO: 17.9;CACO-2: 22.7;MCF7: 8.7;SK-BR-3: 9.3 +LAMA5 ENSG00000130702 Laminin subunit alpha 5 20 62307955-62367312 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054609, CAB078157 Enhanced Supported Nucleoplasm
Vesicles Expressed in all Tissue enhanced skin: 42.1 placenta: 28.9 Cell line enhanced CACO-2: 131.3 +OSBPL2 DFNA67, KIAA0772, ORP-2 ENSG00000130703 Oxysterol binding protein like 2 20 62231922-62296213 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041127, HPA042659 Uncertain Approved Cytosol Renal cancer:4.20e-5 (favourable) Expressed in all Expressed in all skin: 49.7 Expressed in all +ADRM1 ARM1, GP110, Rpn13 ENSG00000130706 Adhesion regulating molecule 1 20 62302093-62308862 Predicted intracellular proteins Evidence at protein level HPA042266 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:9.02e-6 (unfavourable) Expressed in all Expressed in all testis: 108.5 Expressed in all +ASS1 ASS, CTLN1 ENSG00000130707 Argininosuccinate synthase 1 9 130444929-130501274 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020896, HPA020934 Enhanced Approved Nucleoplasm
Cytosol Endometrial cancer:8.14e-9 (unfavourable) Expressed in all Tissue enhanced kidney: 1259.9;liver: 1027.3 fallopian tube: 261.5 Cell line enhanced BJ hTERT+: 709.0;HaCaT: 734.6;RPMI-8226: 956.8;THP-1: 690.3 +PRDM12 ENSG00000130711 PR/SET domain 12 9 130664594-130682981 Disease related genes, Predicted secreted proteins Evidence at protein level HPA043143 Uncertain Approved Nucleus Not detected Not detected cerebral cortex: 0.3 Cell line enriched 16 RH-30: 15.6 +EXOSC2 hRrp4p, p7, RRP4, Rrp4p ENSG00000130713 Exosome component 2 9 130693721-130704894 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021756, HPA021790 Approved Supported Nucleus
Nucleoli Liver cancer:1.39e-5 (unfavourable), Endometrial cancer:4.36e-4 (unfavourable) Expressed in all Expressed in all endometrium: 21.4 Expressed in all +POMT1 LGMD2K ENSG00000130714 Protein O-mannosyltransferase 1 9 131502902-131523806 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA065252 Approved Golgi apparatus Pancreatic cancer:3.90e-5 (favourable), Renal cancer:4.68e-5 (favourable) Expressed in all Expressed in all testis: 62.7 Expressed in all +UCK1 FLJ12255, URK1 ENSG00000130717 Uridine-cytidine kinase 1 9 131523801-131531268 Enzymes, Predicted intracellular proteins Evidence at protein level HPA050969 Approved Approved Nucleus Renal cancer:2.21e-7 (favourable), Cervical cancer:3.19e-4 (favourable) Expressed in all Expressed in all thyroid gland: 31.2 Expressed in all +FIBCD1 FLJ14810 ENSG00000130720 Fibrinogen C domain containing 1 9 130902438-130939286 Predicted intracellular proteins Evidence at protein level HPA053898, HPA055353 Uncertain Supported Cell Junctions Mixed Tissue enhanced adrenal gland: 4.7;parathyroid gland: 8.6;testis: 5.3 cerebral cortex: 2.5 Cell line enhanced MCF7: 25.2;RPTEC TERT1: 18.5;U-2 OS: 17.4;U-251 MG: 11.7 +PRRC2B BAT2L, BAT2L1, KIAA0515, LQFBS-1, MGC10526 ENSG00000130723 Proline rich coiled-coil 2B 9 131394093-131500197 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021022, HPA064301 Uncertain Approved Nuclear bodies
Cytosol Renal cancer:5.42e-9 (favourable) Expressed in all Expressed in all cerebral cortex: 153.7 Expressed in all +CHMP2A BC-2, CHMP2, VPS2, VPS2A ENSG00000130724 Charged multivesicular body protein 2A 19 58551566-58555124 Predicted intracellular proteins Evidence at protein level HPA041153, HPA042031 Enhanced Approved Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all thyroid gland: 191.7 Expressed in all +UBE2M hUbc12, UBC12 ENSG00000130725 Ubiquitin conjugating enzyme E2 M 19 58555712-58558960 Predicted intracellular proteins Evidence at protein level CAB004993, HPA054551, HPA057800 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all Expressed in all cerebral cortex: 108.0 Expressed in all +TRIM28 KAP1, PPP1R157, RNF96, TF1B, TIF1B ENSG00000130726 Tripartite motif containing 28 19 58544091-58550722 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010066, HPA064033 Enhanced Enhanced Nucleoplasm Liver cancer:1.85e-6 (unfavourable) Expressed in all Expressed in all ovary: 215.8 Expressed in all +METTL26 C16orf13, MGC13114 ENSG00000130731 Methyltransferase like 26 16 634427-636366 Predicted intracellular proteins Evidence at protein level HPA044004 Uncertain Renal cancer:1.73e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 43.0 Expressed in all +YIPF2 FinGER2, MGC3262 ENSG00000130733 Yip1 domain family member 2 19 10922185-10928681 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019902 Approved Approved Golgi apparatus
Mitochondria Expressed in all Expressed in all testis: 72.9 Expressed in all +ATG4D APG4-D, APG4D, AUTL4 ENSG00000130734 Autophagy related 4D cysteine peptidase 19 10543895-10553418 Enzymes, Predicted intracellular proteins Evidence at protein level HPA067683 Approved Renal cancer:2.39e-7 (favourable), Cervical cancer:3.18e-5 (favourable), Stomach cancer:5.03e-4 (favourable), Pancreatic cancer:9.95e-4 (favourable) Expressed in all Expressed in all small intestine: 25.2 Mixed +EIF2S3 EIF2, EIF2G, EIF2gamma ENSG00000130741 Eukaryotic translation initiation factor 2 subunit gamma X 24054716-24077971 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012471 Approved Renal cancer:5.44e-6 (unfavourable), Liver cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all ovary: 179.5 Expressed in all +TMEM160 FLJ20512 ENSG00000130748 Transmembrane protein 160 19 47045907-47048630 Predicted membrane proteins Evidence at protein level HPA055904 Uncertain Expressed in all Mixed cerebral cortex: 21.0 Expressed in all +ZC3H4 C19orf7, KIAA1064 ENSG00000130749 Zinc finger CCCH-type containing 4 19 47064187-47113752 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA040934, HPA041068 Supported Enhanced Nucleoplasm
Cytosol Urothelial cancer:2.23e-4 (favourable) Expressed in all Expressed in all spleen: 13.5 Expressed in all +NPAS1 bHLHe11, MOP5, PASD5 ENSG00000130751 Neuronal PAS domain protein 1 19 47019820-47045775 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043364, HPA072259 Approved Approved Nucleoplasm Tissue enhanced Group enriched 5 cerebral cortex: 3.9;skin: 4.4;spleen: 1.8;stomach: 2.6 lymph node: 0.6 Cell line enhanced HEK 293: 10.1;NB-4: 11.4 +GMFG ENSG00000130755 Glia maturation factor gamma 19 39328353-39342372 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002954 Uncertain Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:9.11e-6 (unfavourable), Cervical cancer:7.35e-4 (favourable) Expressed in all Expressed in all spleen: 308.1 Cell line enhanced HMC-1: 476.8;Karpas-707: 305.6;REH: 329.6;THP-1: 378.5;U-937: 301.7 +MAP3K10 MEKK10, MLK2, MST ENSG00000130758 Mitogen-activated protein kinase kinase kinase 10 19 40191744-40215575 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007039 Approved Approved Nucleus
Actin filaments
Cytosol Urothelial cancer:2.13e-4 (favourable), Head and neck cancer:8.69e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 31.1 testis: 7.1 Mixed +ARHGEF16 GEF16, NBR ENSG00000130762 Rho guanine nucleotide exchange factor 16 1 3454426-3481113 Predicted intracellular proteins Evidence at protein level HPA010609 Approved Renal cancer:1.24e-10 (favourable), Liver cancer:1.82e-4 (unfavourable) Mixed Tissue enhanced duodenum: 42.1 small intestine: 35.9 Cell line enhanced CAPAN-2: 48.8;MCF7: 24.6;SK-BR-3: 25.6 +LRRC47 KIAA1185, RP1-286D6.3 ENSG00000130764 Leucine rich repeat containing 47 1 3778558-3796504 Predicted intracellular proteins Evidence at protein level HPA008512, HPA012018 Enhanced Supported Nucleoli fibrillar center Renal cancer:2.75e-4 (favourable), Liver cancer:3.25e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 19.7 Expressed in all +SESN2 DKFZp761M0212, HI95, SES2, SEST2 ENSG00000130766 Sestrin 2 1 28259527-28282491 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018191 Uncertain Approved Cytosol Liver cancer:4.78e-4 (unfavourable) Expressed in all Mixed bone marrow: 25.6 Expressed in all +SMPDL3B ASML3B ENSG00000130768 Sphingomyelin phosphodiesterase acid like 3B 1 27934993-27959157 Predicted secreted proteins Evidence at protein level HPA030561 Approved Golgi apparatus
Cytosol Mixed Mixed rectum: 25.6 Cell line enhanced BEWO: 44.0;CAPAN-2: 31.4;SK-BR-3: 34.4;T-47d: 31.2 +ATPIF1 ATPI, ATPIP, IP, MGC1167, MGC8898 ENSG00000130770 ATPase inhibitory factor 1 1 28236109-28246906 Predicted intracellular proteins Evidence at protein level HPA027999 Supported Enhanced Mitochondria Endometrial cancer:6.38e-8 (favourable), Ovarian cancer:8.20e-4 (favourable) Expressed in all Expressed in all heart muscle: 388.7 Expressed in all +MED18 FLJ20045, p28b ENSG00000130772 Mediator complex subunit 18 1 28329002-28335967 Predicted intracellular proteins Evidence at protein level HPA027429 Uncertain Approved Nucleoplasm Renal cancer:8.38e-5 (favourable), Liver cancer:1.52e-4 (unfavourable), Endometrial cancer:3.93e-4 (favourable), Stomach cancer:6.72e-4 (favourable) Expressed in all Expressed in all fallopian tube: 13.2 Expressed in all +THEMIS2 C1orf38, ICB-1 ENSG00000130775 Thymocyte selection associated family member 2 1 27872543-27886685 Predicted intracellular proteins Evidence at protein level HPA031096, HPA031097 Uncertain Approved Golgi apparatus Expressed in all Tissue enhanced bone marrow: 137.5 spleen: 117.3 Cell line enhanced Karpas-707: 98.1;U-266/70: 80.2 +CLIP1 CLIP, CLIP-170, CLIP170, CYLN1, RSN ENSG00000130779 CAP-Gly domain containing linker protein 1 12 122271432-122422632 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004399, HPA026678 Approved Supported Microtubule ends
Cytosol Expressed in all Expressed in all parathyroid gland: 158.6 Expressed in all +CCDC62 CT109, ERAP75, FLJ40344, TSP-NY ENSG00000130783 Coiled-coil domain containing 62 12 122774327-122827528 Predicted intracellular proteins Evidence at protein level HPA039021, HPA058741 Approved Approved Nucleoplasm
Plasma membrane Not detected Tissue enriched 146 testis: 116.0 spleen: 0.7 Cell line enhanced U-2 OS: 3.0 +HIP1R FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655 ENSG00000130787 Huntingtin interacting protein 1 related 12 122834453-122862960 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB017187, HPA038135, HPA038136 Enhanced Enhanced Vesicles
Plasma membrane
Cytosol Renal cancer:6.50e-7 (favourable), Urothelial cancer:7.26e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 53.1 Mixed +ZNF317 ENSG00000130803 Zinc finger protein 317 19 9140380-9163424 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042075, HPA048625 Approved Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 20.7 Expressed in all +PPAN BXDC3, SSF, SSF1, SSF2 ENSG00000130810 Peter pan homolog (Drosophila) 19 10106289-10111634 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043265 Approved Expressed in all Expressed in all lymph node: 20.2 Expressed in all +EIF3G eIF3-delta, eIF3-p44, eIF3g, EIF3S4 ENSG00000130811 Eukaryotic translation initiation factor 3 subunit G 19 10115017-10119918 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041997 Approved Enhanced Cytosol Ovarian cancer:3.94e-4 (favourable) Expressed in all Expressed in all ovary: 217.8 Expressed in all +ANGPTL6 AGF, ARP5 ENSG00000130812 Angiopoietin like 6 19 10092338-10102796 Plasma proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced liver: 11.0 lymph node: 3.9 Cell line enriched 9 HMC-1: 51.7 +C19orf66 FLJ11286, RyDEN ENSG00000130813 Chromosome 19 open reading frame 66 19 10086122-10093252 Predicted intracellular proteins Evidence at protein level HPA042001 Approved Supported Nucleoplasm
Cytosol Renal cancer:8.96e-11 (unfavourable), Urothelial cancer:1.35e-4 (favourable), Breast cancer:4.04e-4 (favourable) Expressed in all Mixed fallopian tube: 20.5 Cell line enhanced BJ hTERT+ SV40 Large T+: 44.2;BJ hTERT+ SV40 Large T+ RasG12V: 48.5 +DNMT1 CXXC9, DNMT, MCMT ENSG00000130816 DNA methyltransferase 1 19 10133345-10231286 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002694, CAB005876 Enhanced Enhanced Nucleoplasm Liver cancer:1.46e-4 (unfavourable) Expressed in all Expressed in all placenta: 51.2 Expressed in all +ZNF426 MGC2663 ENSG00000130818 Zinc finger protein 426 19 9523224-9538645 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029342 Approved Approved Nucleoplasm Renal cancer:2.57e-6 (favourable), Urothelial cancer:1.81e-4 (favourable), Head and neck cancer:3.74e-4 (favourable) Expressed in all Mixed esophagus: 22.7 Mixed +SLC6A8 CRTR, CT1 ENSG00000130821 Solute carrier family 6 member 8 X 153688099-153696593 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:1.53e-4 (unfavourable), Thyroid cancer:7.39e-4 (unfavourable) Expressed in all Mixed small intestine: 89.2 Mixed +PNCK CaMK1b, MGC45419 ENSG00000130822 Pregnancy up-regulated nonubiquitous CaM kinase X 153669730-153689010 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007458 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Renal cancer:1.04e-6 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 40.5;seminal vesicle: 52.3 smooth muscle: 22.4 Cell line enriched 7 AN3-CA: 29.8 +DKC1 Cbf5, DKC, dyskerin, NAP57, NOLA4, XAP101 ENSG00000130826 Dyskerin pseudouridine synthase 1 X 154762742-154777689 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000166, HPA000447, HPA001022, CAB033086 Supported Supported Nucleus
Nucleoli fibrillar center Renal cancer:1.46e-9 (unfavourable), Liver cancer:1.39e-5 (unfavourable), Endometrial cancer:2.66e-5 (unfavourable), Head and neck cancer:2.94e-4 (unfavourable), Melanoma:9.13e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 45.5 Expressed in all +PLXNA3 6.3, Plxn3, PLXN4, SEX, XAP-6 ENSG00000130827 Plexin A3 X 154458281-154477779 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA058989 Supported Vesicles
Plasma membrane
Cell Junctions Expressed in all Mixed skin: 12.0 Mixed +DUSP9 MKP-4, MKP4 ENSG00000130829 Dual specificity phosphatase 9 X 153642492-153651326 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003336 Enhanced Approved Endoplasmic reticulum Endometrial cancer:1.60e-4 (unfavourable) Mixed Group enriched 35 kidney: 29.0;placenta: 103.3 testis: 1.8 Cell line enriched 6 Hep G2: 251.7 +MPP1 DXS552E, PEMP ENSG00000130830 Membrane palmitoylated protein 1 X 154778684-154821007 Predicted intracellular proteins Evidence at protein level HPA000167 Approved Nucleoli
Nuclear speckles
Cytosol Renal cancer:4.60e-6 (favourable) Expressed in all Expressed in all placenta: 119.5 Cell line enhanced HEL: 191.8 +ZNF331 RITA, ZNF361, ZNF463 ENSG00000130844 Zinc finger protein 331 19 53520981-53580269 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063157 Approved Nucleoplasm Stomach cancer:4.79e-4 (unfavourable), Thyroid cancer:7.43e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 208.6 Cell line enhanced HEK 293: 73.6 +ZNF236 ENSG00000130856 Zinc finger protein 236 18 76822607-76970727 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008600 Uncertain Expressed in all Mixed testis: 13.3 Mixed +SLC7A10 asc-1 ENSG00000130876 Solute carrier family 7 member 10 19 33208664-33225850 Predicted membrane proteins, Transporters Evidence at transcript level HPA041884, HPA057036 Uncertain Uncertain Nucleus
Nucleoli Mixed Group enriched 24 adipose tissue: 31.6;cerebral cortex: 6.5 breast: 0.8 Cell line enhanced BEWO: 1.8;HSkMC: 1.2;THP-1: 2.6;U-2 OS: 1.1 +LRP3 hLRp105, LRP-3 ENSG00000130881 LDL receptor related protein 3 19 33177603-33208867 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Pancreatic cancer:6.12e-7 (favourable) Expressed in all Mixed ovary: 63.4 Mixed +C12orf65 FLJ38663, SPG55 ENSG00000130921 Chromosome 12 open reading frame 65 12 123232916-123257959 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038194, HPA057595 Uncertain Approved Nucleus
Mitochondria
Cytosol Liver cancer:4.29e-9 (unfavourable), Urothelial cancer:7.82e-5 (favourable) Expressed in all Expressed in all testis: 24.7 Expressed in all +NOL11 DKFZP586L0724 ENSG00000130935 Nucleolar protein 11 17 67717833-67744531 Predicted intracellular proteins Evidence at protein level HPA022010 Supported Enhanced Nucleoli Colorectal cancer:1.00e-6 (favourable), Liver cancer:2.59e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.5 Expressed in all +UBE4B E4, KIAA0684, UBOX3, UFD2 ENSG00000130939 Ubiquitination factor E4B 1 10032832-10181239 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019219 Approved Liver cancer:3.69e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 43.4 Expressed in all +CASZ1 castor, cst, FLJ20321, SRG, ZNF693 ENSG00000130940 Castor zinc finger 1 1 10636604-10796650 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028222, HPA029927 Approved Supported Nucleoplasm
Cytosol Mixed Tissue enhanced skin: 26.9 prostate: 15.9 Cell line enhanced HDLM-2: 12.4;SCLC-21H: 23.3;SK-BR-3: 14.1 +PKDREJ ENSG00000130943 Polycystin (PKD) family receptor for egg jelly 22 46255663-46263355 Predicted membrane proteins Evidence at protein level HPA034587 Enhanced Not detected Tissue enriched 9 testis: 6.2 skin: 0.7 Not detected +HSD17B3 SDR12C2 ENSG00000130948 Hydroxysteroid 17-beta dehydrogenase 3 9 96235306-96302152 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA056833 Enhanced Supported Vesicles Mixed Tissue enriched 15 testis: 74.9 thyroid gland: 4.8 Cell line enhanced HBEC3-KT: 2.6;HEL: 3.2;U-2 OS: 5.8 +NUTM2F DKFZp434I1117, FAM22F ENSG00000130950 NUT family member 2F 9 94318196-94328644 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 12 testis: 1.2 all non-specific tissues: 0.0 Cell line enriched 13 NTERA-2: 1.3 +HABP4 IHABP4, SERBP1L ENSG00000130956 Hyaluronan binding protein 4 9 96450201-96491336 Predicted intracellular proteins Evidence at protein level HPA055969 Approved Renal cancer:1.10e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 73.8 Mixed +FBP2 ENSG00000130957 Fructose-bisphosphatase 2 9 94558720-94593793 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012513, HPA055286 Uncertain Approved Nucleoplasm
Plasma membrane Mixed Tissue enriched 8 skeletal muscle: 266.1 stomach: 32.7 Cell line enhanced BEWO: 3.9;MCF7: 2.4;SiHa: 3.0 +SLC35D2 SQV7L, UGTrel8 ENSG00000130958 Solute carrier family 35 member D2 9 96320706-96383710 Predicted membrane proteins, Transporters Evidence at protein level HPA064047 Approved Enhanced Golgi apparatus Expressed in all Expressed in all small intestine: 72.4 Mixed +PRRG1 PRGP1 ENSG00000130962 Proline rich and Gla domain 1 X 37349275-37457295 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA056029, HPA078129 Uncertain Approved Nucleoplasm
Vesicles
Plasma membrane Renal cancer:2.05e-7 (favourable), Pancreatic cancer:1.22e-4 (unfavourable), Cervical cancer:4.65e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 21.6 Cell line enhanced RPTEC TERT1: 59.3 +UBA1 A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X ENSG00000130985 Ubiquitin like modifier activating enzyme 1 X 47190861-47215128 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000289, HPA001506, CAB019435, CAB073410 Approved Enhanced Nucleoplasm Liver cancer:6.10e-5 (unfavourable), Thyroid cancer:1.78e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 239.4 Expressed in all +RGN RC, SMP30 ENSG00000130988 Regucalcin X 47078355-47093314 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029102, HPA029103 Enhanced Approved Nucleus Renal cancer:5.10e-10 (favourable), Liver cancer:7.55e-4 (favourable) Tissue enriched Tissue enhanced adrenal gland: 202.7;liver: 196.4 kidney: 57.0 Group enriched 6 CACO-2: 17.9;fHDF/TERT166: 5.3;Hep G2: 22.3 +POLN ENSG00000130997 DNA polymerase nu 4 2071918-2242121 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035939, HPA035940 Enhanced Nucleoplasm Mixed Tissue enhanced adipose tissue: 3.0;testis: 4.4 epididymis,prostate: 1.0 Mixed +PPIL4 ENSG00000131013 Peptidylprolyl isomerase like 4 6 149504733-149546038 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031599, HPA031600 Approved Enhanced Nucleoplasm Expressed in all Expressed in all thyroid gland: 48.0 Expressed in all +ULBP2 RAET1H ENSG00000131015 UL16 binding protein 2 6 149942000-149949235 Predicted membrane proteins Evidence at protein level CAB018974 Approved Supported Vesicles
Plasma membrane Glioma:3.69e-4 (unfavourable), Cervical cancer:8.07e-4 (unfavourable) Expressed in all Mixed cerebral cortex,esophagus: 3.0 Cell line enhanced SiHa: 69.8 +AKAP12 AKAP250, SSeCKS ENSG00000131016 A-kinase anchoring protein 12 6 151239999-151358557 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006344, CAB026379, HPA056230 Enhanced Supported Plasma membrane
Cytosol Lung cancer:6.34e-5 (unfavourable), Endometrial cancer:7.08e-4 (unfavourable) Expressed in all Expressed in all testis: 184.5 Cell line enhanced REH: 175.6 +SYNE1 8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B ENSG00000131018 Spectrin repeat containing nuclear envelope protein 1 6 152121684-152637801 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019113 Approved Supported Nucleoplasm
Nuclear membrane Mixed Expressed in all parathyroid gland: 59.2 Mixed +ULBP3 RAET1N ENSG00000131019 UL16 binding protein 3 6 150063150-150069095 Predicted secreted proteins Evidence at protein level HPA056541, HPA063007 Approved Uncertain Vesicles
Microtubule organizing center Mixed Tissue enhanced testis: 11.9;thyroid gland: 8.8 fallopian tube: 3.9 Mixed +LATS1 WARTS ENSG00000131023 Large tumor suppressor kinase 1 6 149658153-149718256 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031804 Approved Uncertain Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 23.6 Expressed in all +EPS8L1 DRC3, FLJ20258, MGC23164, MGC4642 ENSG00000131037 EPS8 like 1 19 55072020-55087923 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041851, HPA043545 Uncertain Supported Cytosol Colorectal cancer:4.44e-4 (unfavourable) Mixed Tissue enhanced skin: 18.4;stomach: 23.5 esophagus: 9.0 Cell line enhanced BEWO: 51.9;T-47d: 24.8 +LILRB2 CD85d, ILT4, LIR-2, LIR2, MIR-10, MIR10 ENSG00000131042 Leukocyte immunoglobulin like receptor B2 19 54273821-54281184 CD markers, Predicted membrane proteins Evidence at protein level Renal cancer:5.45e-7 (unfavourable) Expressed in all Tissue enhanced appendix: 8.7;bone marrow: 20.5;spleen: 10.4 lung: 3.9 Not detected +AAR2 bA234K24.2, C20orf4 ENSG00000131043 AAR2 splicing factor homolog 20 36236459-36270918 Predicted intracellular proteins Evidence at protein level CAB034220, HPA048645 Uncertain Approved Cytosol Liver cancer:1.83e-6 (unfavourable) Expressed in all Expressed in all smooth muscle: 41.9 Expressed in all +TTLL9 C20orf125, dJ310O13.1 ENSG00000131044 Tubulin tyrosine ligase like 9 20 31870702-31944963 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level HPA041772, HPA055676 Uncertain Uncertain Nucleoplasm
Microtubules Tissue enhanced Tissue enhanced fallopian tube: 7.1;testis: 6.3 epididymis: 3.2 Not detected +BPIFA2 bA49G10.1, C20orf70, PSP, SPLUNC2 ENSG00000131050 BPI fold containing family A member 2 20 33161768-33181412 Predicted secreted proteins Evidence at protein level HPA044006 Enhanced Tissue enhanced Tissue enriched 520 salivary gland: 2662.8 epididymis: 5.1 Not detected +RBM39 CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2 ENSG00000131051 RNA binding motif protein 39 20 35701347-35742312 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001591 Supported Supported Nucleoplasm
Nuclear speckles
Microtubules
Microtubule organizing center Renal cancer:2.78e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 123.0 Expressed in all +COX4I2 COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2 ENSG00000131055 Cytochrome c oxidase subunit 4I2 20 31637888-31645006 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Head and neck cancer:6.04e-5 (favourable), Renal cancer:9.78e-4 (unfavourable) Expressed in all Group enriched 5 lung: 42.8;placenta: 157.5 thyroid gland: 19.3 Cell line enriched 5 SH-SY5Y: 1.8 +BPIFA3 bA49G10.4, C20orf71, SPLUNC3 ENSG00000131059 BPI fold containing family A member 3 20 33217310-33227758 Predicted secreted proteins Evidence at protein level HPA062708 Enhanced Not detected Tissue enriched 534 testis: 53.4 all non-specific tissues: 0.0 Not detected +ZNF341 dJ553F4.3 ENSG00000131061 Zinc finger protein 341 20 33731657-33792269 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023240, HPA024607, HPA067108 Uncertain Approved Nucleoplasm
Vesicles Liver cancer:1.87e-4 (unfavourable), Head and neck cancer:3.93e-4 (favourable) Expressed in all Mixed testis: 2.3 Mixed +GGT7 D20S101, dJ18C9.2, GGTL3, GGTL5 ENSG00000131067 Gamma-glutamyltransferase 7 20 34844720-34872860 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013204, HPA013339 Approved Approved Nucleus
Vesicles Endometrial cancer:1.26e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex,parathyroid gland: 50.0 Mixed +DEFB118 C20orf63, DEFB-18, dJ1018D12.3, ESC42 ENSG00000131068 Defensin beta 118 20 31368618-31373923 Predicted secreted proteins Evidence at protein level HPA042634 Enhanced Not detected Tissue enriched 12295 epididymis: 1229.5 all non-specific tissues: 0.0 Not detected +ACSS2 ACAS2, AceCS, ACS, ACSA, dJ1161H23.1 ENSG00000131069 Acyl-CoA synthetase short-chain family member 2 20 34872146-34927962 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004141 Approved Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:2.04e-4 (favourable) Expressed in all Mixed adipose tissue: 55.9 Mixed +EDA2R EDA-A2R, EDAA2R, TNFRSF27, XEDAR ENSG00000131080 Ectodysplasin A2 receptor X 66595637-66639298 Predicted membrane proteins Evidence at protein level HPA054522 Approved Cell Junctions Mixed Mixed thyroid gland: 9.5 Cell line enhanced HSkMC: 24.5;LHCN-M2: 26.7 +ARHGEF9 KIAA0424, PEM-2 ENSG00000131089 Cdc42 guanine nucleotide exchange factor 9 X 63634967-63809274 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035419, HPA055291 Approved Supported Cytosol Renal cancer:1.02e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 80.1 Mixed +C1QL1 C1QRF, C1QTNF14, CRF ENSG00000131094 Complement C1q like 1 17 44959693-44968071 Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.31e-8 (unfavourable) Tissue enriched Tissue enriched 14 cerebral cortex: 38.4 prostate: 2.6 Cell line enhanced SCLC-21H: 49.2;SH-SY5Y: 31.5;U-2 OS: 108.2;U-87 MG: 32.8 +GFAP FLJ45472 ENSG00000131095 Glial fibrillary acidic protein 17 44903161-44916937 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000039, HPA056030, HPA063513 Enhanced Supported Supported Intermediate filaments Tissue enriched Tissue enriched 398 cerebral cortex: 3768.4 bone marrow: 9.4 Mixed +PYY PYY1 ENSG00000131096 Peptide YY 17 43952738-44004469 Predicted secreted proteins Evidence at protein level HPA010973, CAB016734 Enhanced Group enriched Group enriched 15 colon: 52.6;rectum: 39.2;small intestine: 27.4 duodenum: 2.5 Cell line enhanced HMC-1: 2.6 +HIGD1B CLST11240, CLST11240-15 ENSG00000131097 HIG1 hypoxia inducible domain family member 1B 17 44846353-44850480 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Group enriched 6 lung: 55.4;placenta: 153.8 gallbladder: 18.2 Mixed +ATP6V1E1 ATP6E, ATP6E2, ATP6V1E, P31, Vma4 ENSG00000131100 ATPase H+ transporting V1 subunit E1 22 17592136-17628818 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB009528, CAB018699, HPA029196 Enhanced Approved Nucleoplasm Renal cancer:7.66e-8 (favourable), Liver cancer:1.56e-5 (unfavourable), Prostate cancer:4.18e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 301.3 Expressed in all +ZNF227 ENSG00000131115 Zinc finger protein 227 19 44207547-44237268 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030573 Uncertain Approved Plasma membrane Urothelial cancer:2.64e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 18.7 Mixed +ZNF428 C19orf37, MGC51082, Zfp428 ENSG00000131116 Zinc finger protein 428 19 43607219-43619874 Predicted intracellular proteins Evidence at protein level HPA042596, HPA048072 Uncertain Approved Nucleoli
Mitochondria Pancreatic cancer:3.60e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 71.5 Expressed in all +TEX101 CT131, MGC4766, SGRG, SPATA44 ENSG00000131126 Testis expressed 101 19 43401496-43418597 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA041915, HPA042513 Enhanced Mixed Tissue enriched 108 testis: 173.9 skin: 1.6 Not detected +ZNF141 D4S90, pHZ-44 ENSG00000131127 Zinc finger protein 141 4 337814-384864 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Urothelial cancer:4.76e-4 (favourable) Expressed in all Mixed adrenal gland,thyroid gland: 14.9 Mixed +CCL25 Ckb15, SCYA25, TECK ENSG00000131142 C-C motif chemokine ligand 25 19 8052767-8062650 Predicted secreted proteins Evidence at protein level HPA055883 Uncertain Group enriched Group enriched 317 duodenum: 529.5;small intestine: 653.7 lymph node: 1.8 Cell line enhanced BEWO: 2.7;HEL: 2.7;REH: 5.6;SH-SY5Y: 2.0 +COX4I1 COX4, COX4-1 ENSG00000131143 Cytochrome c oxidase subunit 4I1 16 85798633-85807044 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA002485, CAB004080 Supported Supported Mitochondria Renal cancer:2.56e-8 (favourable) Expressed in all Expressed in all heart muscle: 1085.8 Expressed in all +EMC8 C16orf2, C16orf4, COX4NB, FAM158B, NOC4 ENSG00000131148 ER membrane protein complex subunit 8 16 85771758-85799608 Predicted intracellular proteins Evidence at protein level HPA049476 Approved Supported Cytosol Renal cancer:6.39e-4 (favourable), Liver cancer:8.49e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 17.4 Expressed in all +GSE1 KIAA0182 ENSG00000131149 Gse1 coiled-coil protein 16 85169525-85676204 Predicted intracellular proteins Evidence at protein level HPA036365 Uncertain Approved Nucleoplasm
Mitochondria Pancreatic cancer:5.20e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 83.4 Expressed in all +RP11-178L8.4 ENSG00000131152 16 87302876-87334273 Predicted intracellular proteins Evidence at transcript level HPA040850 Uncertain Not detected Not detected duodenum,endometrium,lymph node,skeletal muscle: 0.6 Mixed +GINS2 Pfs2, PSF2 ENSG00000131153 GINS complex subunit 2 16 85676198-85690073 Predicted intracellular proteins Evidence at protein level HPA057285 Uncertain Supported Nucleoplasm Expressed in all Mixed testis: 12.2 Cell line enhanced U-698: 182.9 +CHMP1A CHMP1, KIAA0047, PCOLN3, PRSM1, Vps46A ENSG00000131165 Charged multivesicular body protein 1A 16 89644431-89657845 Disease related genes, Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all parathyroid gland: 53.1 Expressed in all +SH3BGRL MGC117402 ENSG00000131171 SH3 domain binding glutamate rich protein like X 81201943-81298547 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051248 Approved Approved Vesicles Stomach cancer:4.08e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 360.6 Mixed +COX7B ENSG00000131174 Cytochrome c oxidase subunit 7B X 77899438-77907373 Disease related genes, Predicted membrane proteins Evidence at protein level HPA058041 Uncertain Renal cancer:6.80e-6 (favourable), Urothelial cancer:2.43e-4 (favourable) Expressed in all Expressed in all heart muscle: 65.4 Expressed in all +SLC34A1 NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2 ENSG00000131183 Solute carrier family 34 member 1 5 177379235-177398848 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA051255 Approved Supported Nuclear speckles
Plasma membrane
Mitotic spindle Tissue enriched Tissue enriched 164 kidney: 161.7 liver: 0.9 Group enriched 12 HEL: 2.1;U-937: 1.2 +F12 ENSG00000131187 Coagulation factor XII 5 177402140-177409576 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA003825 Approved Liver cancer:4.63e-5 (favourable), Renal cancer:7.09e-4 (unfavourable) Tissue enriched Tissue enriched 78 liver: 141.6 bone marrow: 1.8 Cell line enhanced HDLM-2: 6.4;MCF7: 6.7;PC-3: 5.8;SH-SY5Y: 4.5 +PRR7 MGC10772 ENSG00000131188 Proline rich 7, synaptic 5 177446445-177456286 Predicted intracellular proteins Evidence at transcript level HPA046636 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.50e-4 (unfavourable), Renal cancer:1.98e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 8.1 bone marrow: 3.7 Mixed +NFATC1 NF-ATC, NFAT2, NFATc ENSG00000131196 Nuclear factor of activated T-cells 1 18 79395856-79529325 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004513, HPA071732 Enhanced Supported Nucleoplasm
Nuclear bodies Expressed in all Mixed lymph node: 24.7 Cell line enhanced U-698: 42.3 +IDO1 IDO, INDO ENSG00000131203 Indoleamine 2,3-dioxygenase 1 8 39902275-39928444 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA023072, HPA023149, HPA027772, CAB072820 Enhanced Renal cancer:1.12e-7 (unfavourable), Ovarian cancer:3.32e-4 (favourable), Melanoma:5.27e-4 (favourable) Expressed in all Tissue enhanced placenta: 149.4 lymph node: 57.3 Cell line enriched 7 EFO-21: 54.8 +GJA9 CX58, CX59, GJA10 ENSG00000131233 Gap junction protein alpha 9 1 38874451-38881587 Predicted membrane proteins Evidence at transcript level HPA067850 Uncertain Not detected Tissue enhanced testis: 2.0 skin: 0.5 Not detected +CAP1 CAP ENSG00000131236 Adenylate cyclase associated protein 1 1 40040233-40072649 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030124 Approved Supported Cytosol Liver cancer:1.44e-6 (unfavourable) Expressed in all Expressed in all appendix: 417.0 Expressed in all +PPT1 CLN1, INCL, PPT ENSG00000131238 Palmitoyl-protein thioesterase 1 1 40072705-40097703 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021546 Supported Liver cancer:6.98e-8 (unfavourable) Expressed in all Expressed in all spleen: 193.0 Expressed in all +RAB11FIP4 FLJ00131, KIAA1821, MGC11316, RAB11-FIP4 ENSG00000131242 RAB11 family interacting protein 4 17 31391624-31538217 Predicted intracellular proteins Evidence at protein level HPA021595 Approved Renal cancer:7.74e-8 (favourable), Stomach cancer:1.22e-4 (favourable), Colorectal cancer:2.70e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 67.9 testis: 42.4 Cell line enhanced BEWO: 62.0;HMC-1: 36.4 +RLIM MGC15161, NY-REN-43, RNF12 ENSG00000131263 Ring finger protein, LIM domain interacting X 74585217-74614617 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018895 Approved Supported Nucleoplasm
Cytosol Thyroid cancer:6.04e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 29.0 Expressed in all +CDX4 ENSG00000131264 Caudal type homeobox 4 X 73447254-73455245 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056528 Uncertain Tissue enriched Tissue enriched 8 skin: 1.3 seminal vesicle,testis: 0.1 Not detected +ABCB7 ABC7, ASAT, Atm1p, EST140535 ENSG00000131269 ATP binding cassette subfamily B member 7 X 75053172-75156732 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA034982 Approved Supported Mitochondria Renal cancer:5.31e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 21.7 Expressed in all +TRAF3 CAP-1, CD40bp, CRAF1, LAP1 ENSG00000131323 TNF receptor associated factor 3 14 102777476-102911500 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002933 Uncertain Liver cancer:1.02e-5 (unfavourable), Pancreatic cancer:2.42e-5 (favourable) Expressed in all Mixed appendix: 25.7 Expressed in all +HAUS8 HICE1, MGC20533, NY-SAR-48 ENSG00000131351 HAUS augmin like complex subunit 8 19 17049729-17075625 Predicted intracellular proteins Evidence at protein level HPA039406 Uncertain Cervical cancer:9.54e-4 (favourable) Expressed in all Mixed testis: 16.7 Mixed +ADGRE3 EMR3 ENSG00000131355 Adhesion G protein-coupled receptor E3 19 14619117-14690027 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA015638 Uncertain Not detected Tissue enhanced appendix: 8.7;spleen: 8.6 lung: 3.9 Cell line enriched 50 HMC-1: 39.7 +MRPS25 DKFZp313H0817, FLJ00023, MRP-S25, RPMS25 ENSG00000131368 Mitochondrial ribosomal protein S25 3 15042460-15065335 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043490 Approved Enhanced Mitochondria Renal cancer:3.60e-7 (favourable) Expressed in all Expressed in all testis: 32.9 Expressed in all +SH3BP5 Sab ENSG00000131370 SH3 domain binding protein 5 3 15254853-15341368 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036445, HPA057988 Uncertain Supported Nucleoplasm
Nuclear bodies Renal cancer:8.17e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 221.2 Expressed in all +HACL1 2-HPCL, HPCL, PHYH2 ENSG00000131373 2-hydroxyacyl-CoA lyase 1 3 15560704-15601852 Predicted intracellular proteins Evidence at protein level HPA035496, HPA035497 Approved Renal cancer:2.63e-5 (favourable) Expressed in all Expressed in all duodenum: 50.9 Expressed in all +TBC1D5 KIAA0210 ENSG00000131374 TBC1 domain family member 5 3 17157162-18444817 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035125, HPA035126 Uncertain Supported Golgi apparatus
Vesicles Renal cancer:1.75e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 56.9 Expressed in all +CAPN7 PalBH ENSG00000131375 Calpain 7 3 15206152-15252918 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046617 Uncertain Colorectal cancer:4.85e-5 (favourable) Expressed in all Expressed in all thyroid gland: 39.4 Expressed in all +RFTN1 FLJ23866, KIAA0084, MIG2, Raftlin ENSG00000131378 Raftlin, lipid raft linker 1 3 16313574-16514026 Predicted intracellular proteins Evidence at protein level HPA048725 Approved Renal cancer:1.29e-7 (unfavourable) Expressed in all Mixed lymph node: 135.3 Cell line enhanced HDLM-2: 165.3;SH-SY5Y: 142.4 +C3orf20 DKFZP434N1817 ENSG00000131379 Chromosome 3 open reading frame 20 3 14675099-14773034 Predicted intracellular proteins Evidence at protein level HPA039584 Uncertain Not detected Tissue enriched 29 testis: 10.4 lymph node,tonsil: 0.3 Cell line enhanced Daudi: 2.9;HEL: 7.7;U-698: 4.4 +RBSN ZFYVE20 ENSG00000131381 Rabenosyn, RAB effector 3 15070073-15099163 Predicted intracellular proteins Evidence at protein level HPA044878 Approved Enhanced Vesicles Expressed in all Expressed in all cerebral cortex: 30.7 Expressed in all +GALNT15 GALNT7, GALNTL2, pp-GalNAc-T15 ENSG00000131386 Polypeptide N-acetylgalactosaminyltransferase 15 3 16174649-16231992 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017076 Uncertain Approved Golgi apparatus
Cytosol Tissue enriched Tissue enhanced adipose tissue: 36.3;cerebral cortex: 41.2;placenta: 43.0 breast: 18.3 Group enriched 11 ASC diff: 91.0;ASC TERT1: 90.9;HSkMC: 72.4;U-2197: 22.3 +SLC6A6 TAUT ENSG00000131389 Solute carrier family 6 member 6 3 14402576-14489349 Predicted membrane proteins, Transporters Evidence at protein level HPA015028, HPA016488 Enhanced Approved Cell Junctions
Cytosol Glioma:1.09e-7 (unfavourable), Endometrial cancer:5.22e-5 (favourable), Liver cancer:8.78e-4 (unfavourable) Expressed in all Mixed ovary: 50.8 Mixed +KCNC3 Kv3.3, SCA13 ENSG00000131398 Potassium voltage-gated channel subfamily C member 3 19 50311937-50333515 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA018041 Approved Renal cancer:1.23e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 39.9 cerebral cortex: 19.8 Cell line enhanced HMC-1: 26.4;SK-BR-3: 15.3;T-47d: 18.4;U-2 OS: 13.8 +NAPSA KAP, Kdap, NAP1, NAPA ENSG00000131400 Napsin A aspartic peptidase 19 50358477-50365830 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB009591, HPA045280, HPA047236, HPA047744 Enhanced Renal cancer:1.21e-4 (favourable) Tissue enriched Tissue enriched 14 lung: 1412.2 kidney: 101.4 Cell line enriched 23 U-698: 27.1 +NR1H2 LXR-b, NER, NER-I, RIP15, UNR ENSG00000131408 Nuclear receptor subfamily 1 group H member 2 19 50329653-50382982 Cancer-related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056838, HPA070212 Uncertain Approved Nucleoplasm Colorectal cancer:9.86e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 87.6 Expressed in all +LRRC4B DKFZp761A179, HSM, LRIG4 ENSG00000131409 Leucine rich repeat containing 4B 19 50516892-50568045 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA058986 Uncertain Group enriched Tissue enhanced cerebral cortex: 61.4 cervix, uterine: 12.9 Cell line enhanced HMC-1: 29.7;SH-SY5Y: 31.3;U-2 OS: 28.7 +PDLIM4 RIL ENSG00000131435 PDZ and LIM domain 4 5 132257671-132273454 Predicted intracellular proteins Evidence at protein level HPA011912 Uncertain Approved Actin filaments
Cytosol Mixed Mixed smooth muscle: 61.9 Cell line enhanced hTEC/SVTERT24-B: 117.7 +KIF3A FLA10, KLP-20 ENSG00000131437 Kinesin family member 3A 5 132692628-132737638 Predicted intracellular proteins Evidence at protein level CAB037085 Approved Approved Nucleoplasm
Intermediate filaments
Cytosol Expressed in all Tissue enhanced cerebral cortex: 82.8 testis: 43.9 Expressed in all +MGAT1 GLCNAC-TI, GLYT1, GNT-1, GnTI, MGAT ENSG00000131446 Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 5 180784782-180815652 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017432 Approved Renal cancer:8.65e-4 (unfavourable) Expressed in all Expressed in all spleen: 118.4 Expressed in all +GFPT2 GFAT2 ENSG00000131459 Glutamine-fructose-6-phosphate transaminase 2 5 180300690-180353387 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA056892, HPA059910 Uncertain Supported Vesicles Renal cancer:2.58e-14 (unfavourable), Lung cancer:2.95e-4 (unfavourable), Thyroid cancer:3.47e-4 (unfavourable), Cervical cancer:9.09e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 90.9 appendix: 25.7 Cell line enhanced ASC TERT1: 138.7;hTEC/SVTERT24-B: 242.9;U-87 MG: 409.1 +TUBG1 TUBG, TUBGCP1 ENSG00000131462 Tubulin gamma 1 17 42609676-42615234 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004608 Enhanced Liver cancer:1.08e-8 (unfavourable), Renal cancer:6.48e-5 (unfavourable), Endometrial cancer:8.99e-4 (favourable) Expressed in all Tissue enriched 6 testis: 242.8 smooth muscle: 40.2 Expressed in all +PSME3 Ki, PA28-gamma, PA28G, REG-GAMMA ENSG00000131467 Proteasome activator subunit 3 17 42824385-42843758 Predicted intracellular proteins Evidence at protein level CAB008388, HPA012510 Supported Enhanced Nucleoplasm Liver cancer:5.41e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 106.3 Expressed in all +RPL27 L27 ENSG00000131469 Ribosomal protein L27 17 42998273-43002959 Cancer-related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA002649 Approved Renal cancer:7.80e-8 (unfavourable) Expressed in all Expressed in all breast: 2437.8 Expressed in all +PSMC3IP GT198, Hop2, HUMGT198A, TBPIP ENSG00000131470 PSMC3 interacting protein 17 42572315-42577831 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044439 Enhanced Supported Nucleoplasm Renal cancer:9.41e-4 (unfavourable) Expressed in all Tissue enhanced testis: 32.2 fallopian tube: 9.6 Expressed in all +AOC3 HPAO, VAP-1, VAP1 ENSG00000131471 Amine oxidase, copper containing 3 17 42851184-42858130 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000980, CAB025797 Enhanced Approved Golgi apparatus
Cytosol Renal cancer:1.79e-5 (unfavourable), Colorectal cancer:3.68e-4 (unfavourable), Urothelial cancer:6.98e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 450.1 smooth muscle: 205.7 Cell line enriched 17 ASC diff: 210.1 +ACLY ACL, ATPCL, CLATP ENSG00000131473 ATP citrate lyase 17 41866908-41930542 Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007783, HPA022434, HPA022953, HPA022959, HPA028758 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Cervical cancer:1.79e-4 (unfavourable), Liver cancer:3.66e-4 (unfavourable) Expressed in all Expressed in all prostate: 100.5 Expressed in all +VPS25 DERP9, EAP20, MGC10540 ENSG00000131475 Vacuolar protein sorting 25 homolog 17 42773436-42779599 Predicted intracellular proteins Evidence at protein level CAB004978, HPA052217, HPA057284 Uncertain Approved Centrosome Colorectal cancer:3.18e-4 (favourable) Expressed in all Expressed in all fallopian tube: 93.3 Expressed in all +RAMP2 ENSG00000131477 Receptor activity modifying protein 2 17 42758447-42763041 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA052020 Approved Vesicles Expressed in all Mixed lung: 178.6 Cell line enhanced ASC diff: 78.4;EFO-21: 72.9;HUVEC TERT2: 29.7 +AOC2 DAO2, RAO ENSG00000131480 Amine oxidase, copper containing 2 17 42844600-42850707 Enzymes, Predicted secreted proteins Evidence at protein level HPA057779 Uncertain Urothelial cancer:2.47e-4 (favourable) Tissue enhanced Group enriched 5 adipose tissue: 6.2;testis: 5.8 spleen: 1.2 Cell line enhanced ASC diff: 7.7 +G6PC G6PT, GSD1a ENSG00000131482 Glucose-6-phosphatase catalytic subunit 17 42900797-42913369 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA052324 Enhanced Renal cancer:3.79e-5 (favourable), Liver cancer:5.42e-5 (favourable) Tissue enriched Tissue enhanced kidney: 89.1;liver: 147.3 small intestine: 33.2 Not detected +NDUFA2 B8 ENSG00000131495 NADH:ubiquinone oxidoreductase subunit A2 5 140638740-140647785 Predicted intracellular proteins Evidence at protein level HPA035933 Uncertain Cervical cancer:6.53e-4 (favourable) Expressed in all Expressed in all adrenal gland: 117.4 Expressed in all +ANKHD1 FLJ10042, FLJ11979, FLJ14127, FLJ20288, KIAA1085, MASK, MASK1 ENSG00000131503 Ankyrin repeat and KH domain containing 1 5 140401814-140539856 Predicted intracellular proteins Evidence at protein level HPA008718 Approved Mixed Expressed in all parathyroid gland: 74.5 Expressed in all +DIAPH1 DFNA1, hDIA1, LFHL1 ENSG00000131504 Diaphanous related formin 1 5 141515016-141619055 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004916, HPA076913 Approved Approved Plasma membrane Renal cancer:1.29e-5 (favourable), Pancreatic cancer:7.81e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 73.6 Expressed in all +NDFIP1 MGC10924, N4WBP5 ENSG00000131507 Nedd4 family interacting protein 1 5 142108505-142154443 Predicted membrane proteins Evidence at protein level HPA009682 Approved Head and neck cancer:2.33e-7 (unfavourable), Renal cancer:2.39e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 246.0 Expressed in all +UBE2D2 UBC4, UbcH5B ENSG00000131508 Ubiquitin conjugating enzyme E2 D2 5 139526431-139628433 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA003920 Approved Approved Plasma membrane
Cytosol Liver cancer:9.63e-7 (unfavourable), Renal cancer:2.09e-5 (unfavourable), Colorectal cancer:5.09e-5 (favourable), Endometrial cancer:5.90e-4 (favourable) Expressed in all Expressed in all testis: 239.4 Expressed in all +EXOC4 KIAA1699, MGC27170, SEC8, SEC8L1, Sec8p ENSG00000131558 Exocyst complex component 4 7 133253073-134066589 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA031443, HPA031444 Approved Supported Nucleus
Nucleoli Renal cancer:6.85e-5 (favourable), Pancreatic cancer:6.19e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.9 Expressed in all +ACAP3 CENTB5, KIAA1716 ENSG00000131584 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 1 1292376-1309609 Predicted intracellular proteins Evidence at protein level HPA049317, HPA058381 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all Expressed in all cerebral cortex: 26.5 Expressed in all +C1orf159 FLJ20584 ENSG00000131591 Chromosome 1 open reading frame 159 1 1081818-1116361 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010019 Approved Approved Nucleoli fibrillar center
Cytosol Renal cancer:1.77e-6 (unfavourable), Liver cancer:9.58e-6 (unfavourable), Urothelial cancer:1.62e-4 (favourable) Expressed in all Mixed skin: 15.3 Expressed in all +ANO1 DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A ENSG00000131620 Anoctamin 1 11 70078302-70189528 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA032148, HPA057356 Enhanced Renal cancer:4.09e-6 (unfavourable), Endometrial cancer:4.58e-6 (favourable), Head and neck cancer:7.28e-5 (unfavourable), Pancreatic cancer:1.70e-4 (unfavourable), Lung cancer:2.40e-4 (unfavourable) Expressed in all Tissue enhanced epididymis: 220.9;seminal vesicle: 298.5 skin: 115.8 Group enriched 5 A-431: 121.8;CAPAN-2: 182.7;HaCaT: 224.5 +PPFIA1 LIP.1, LIPRIN ENSG00000131626 PTPRF interacting protein alpha 1 11 70270700-70384403 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008272, CAB017032, HPA042271 Uncertain Enhanced Focal adhesion sites
Cytosol Renal cancer:3.76e-4 (favourable), Head and neck cancer:5.58e-4 (unfavourable), Pancreatic cancer:8.26e-4 (unfavourable) Expressed in all Expressed in all testis: 57.2 Expressed in all +TMEM204 C16orf30, CLP24, FLJ20898 ENSG00000131634 Transmembrane protein 204 16 1528688-1555580 Predicted membrane proteins Evidence at transcript level HPA014028 Approved Liver cancer:4.76e-4 (favourable), Melanoma:7.89e-4 (unfavourable) Expressed in all Mixed adipose tissue: 40.6 Cell line enhanced BJ: 13.1;BJ hTERT+: 17.0;fHDF/TERT166: 11.0;HHSteC: 30.6;HSkMC: 10.6 +KREMEN2 KRM2, MGC10791 ENSG00000131650 Kringle containing transmembrane protein 2 16 2963944-2968383 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA003223 Uncertain Approved Nucleoli Lung cancer:8.98e-4 (unfavourable) Mixed Tissue enhanced skin: 6.9 cerebral cortex: 2.1 Cell line enhanced HMC-1: 24.6;RPMI-8226: 19.1 +THOC6 fSAP35, MGC2655, WDR58 ENSG00000131652 THO complex 6 16 3024027-3027755 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA052953 Uncertain Supported Nucleoplasm
Nuclear speckles Renal cancer:4.40e-4 (unfavourable) Expressed in all Expressed in all skin: 29.2 Expressed in all +TRAF7 DKFZp586I021, MGC7807, RFWD1, RNF119 ENSG00000131653 TNF receptor associated factor 7 16 2155698-2178129 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA041229 Approved Supported Vesicles
Plasma membrane Expressed in all Expressed in all skin: 40.6 Expressed in all +BARX1 ENSG00000131668 BARX homeobox 1 9 93951622-93955372 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055858 Approved Nucleoplasm
Vesicles Endometrial cancer:8.16e-6 (unfavourable), Head and neck cancer:1.02e-4 (unfavourable) Tissue enhanced Tissue enriched 7 stomach: 11.1 testis: 1.5 Group enriched 6 AN3-CA: 27.2;HMC-1: 61.1;NTERA-2: 20.7;THP-1: 19.2 +NINJ1 NIN1 ENSG00000131669 Ninjurin 1 9 93121489-93134288 Predicted membrane proteins Evidence at protein level HPA045063 Uncertain Expressed in all Expressed in all bone marrow: 158.2 Mixed +CA6 ENSG00000131686 Carbonic anhydrase 6 1 8945867-8975092 Enzymes, Predicted secreted proteins Evidence at protein level HPA028550, HPA028692 Enhanced Mixed Tissue enriched 154 salivary gland: 3805.4 breast: 24.7 Mixed +NPHP4 KIAA0673, POC10, SLSN4 ENSG00000131697 Nephrocystin 4 1 5862811-5992473 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA065526 Approved Mixed Mixed fallopian tube: 12.5 Mixed +MAP1B MAP5, PPP1R102 ENSG00000131711 Microtubule associated protein 1B 5 72107234-72209570 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009792, HPA022275 Enhanced Enhanced Cytosol Urothelial cancer:8.22e-5 (unfavourable) Tissue enriched Tissue enriched 5 cerebral cortex: 187.6 smooth muscle: 36.8 Cell line enhanced TIME: 228.1 +RHOXF2 CT107, PEPP-2, PEPP2, THG1 ENSG00000131721 Rhox homeobox family member 2 X 120158561-120165630 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003314, CAB020794 Enhanced Tissue enhanced Tissue enriched 184 testis: 20.8 skin: 0.1 Cell line enhanced K-562: 209.3;NB-4: 108.3;THP-1: 42.9;U-266/84: 73.5 +IL13RA1 CD213a1, IL-13Ra, NR4 ENSG00000131724 Interleukin 13 receptor subunit alpha 1 X 118727572-118794539 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA000293 Approved Nucleoplasm
Golgi apparatus Renal cancer:1.19e-8 (unfavourable) Expressed in all Expressed in all lung: 72.0 Mixed +WDR44 DKFZp686L20145, RAB11BP, RPH11 ENSG00000131725 WD repeat domain 44 X 118346073-118449961 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038084, HPA046719 Approved Supported Golgi apparatus Expressed in all Expressed in all parathyroid gland: 23.2 Expressed in all +CKMT2 SMTCK ENSG00000131730 Creatine kinase, mitochondrial 2 5 81233285-81266397 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051880 Enhanced Mixed Group enriched 22 heart muscle: 710.7;skeletal muscle: 505.3 adrenal gland: 27.9 Cell line enhanced BEWO: 3.3;T-47d: 5.1 +ZCCHC9 DKFZp761J139, PPP1R41 ENSG00000131732 Zinc finger CCHC-type containing 9 5 81301590-81313297 Predicted intracellular proteins Evidence at protein level HPA038404, HPA057521 Uncertain Approved Intermediate filaments Expressed in all Expressed in all placenta: 27.4 Expressed in all +KRT34 Ha-4, KRTHA4 ENSG00000131737 Keratin 34 17 41377650-41382403 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055194, HPA072208 Supported Approved Nucleus
Vesicles Tissue enhanced Tissue enriched 8 cervix, uterine: 4.2 testis: 0.5 Cell line enhanced BJ: 170.4;BJ hTERT+ SV40 Large T+ RasG12V: 45.2;HBF TERT88: 41.4 +KRT33B Ha-3II, KRTHA3B ENSG00000131738 Keratin 33B 17 41363494-41369800 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055194 Supported Tissue enhanced Not detected testis: 0.1 Cell line enhanced BJ: 3.4;hTEC/SVTERT24-B: 1.5;U-2197: 1.0 +TNS4 CTEN ENSG00000131746 Tensin 4 17 40475828-40501597 Predicted intracellular proteins Evidence at protein level Lung cancer:5.16e-4 (unfavourable) Mixed Tissue enhanced skin: 66.6 esophagus: 31.6 Cell line enhanced HaCaT: 123.8;HBEC3-KT: 447.5;hTCEpi: 328.7;hTERT-HME1: 108.8 +TOP2A TOP2 ENSG00000131747 Topoisomerase (DNA) II alpha 17 40388516-40417950 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002448, HPA006458, HPA026773 Enhanced Approved Supported Nucleus
Nucleoli Renal cancer:0.00e+0 (unfavourable), Liver cancer:5.92e-6 (unfavourable), Pancreatic cancer:3.83e-5 (unfavourable), Lung cancer:4.99e-4 (unfavourable) Expressed in all Tissue enhanced testis: 108.5 lymph node: 47.7 Expressed in all +STARD3 es64, MLN64 ENSG00000131748 StAR related lipid transfer domain containing 3 17 39637065-39663484 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level CAB017021 Uncertain Liver cancer:3.60e-5 (unfavourable), Renal cancer:7.70e-4 (unfavourable) Expressed in all Expressed in all testis: 33.3 Expressed in all +RARA NR1B1, RAR ENSG00000131759 Retinoic acid receptor alpha 17 40309192-40357643 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058282 Supported Nucleus
Cytosol Endometrial cancer:2.60e-4 (favourable) Expressed in all Expressed in all gallbladder: 68.6 Expressed in all +PPP1R1B DARPP-32, FLJ20940 ENSG00000131771 Protein phosphatase 1 regulatory inhibitor subunit 1B 17 39626740-39636626 Predicted intracellular proteins Evidence at protein level CAB004026, HPA048630, HPA061142 Approved Approved Mixed Tissue enhanced rectum: 219.9 colon: 209.5 Cell line enhanced CAPAN-2: 11.0;HSkMC: 23.1;SCLC-21H: 31.9 +KHDRBS3 Etle, etoile, SALP, SLM-2, SLM2, T-STAR ENSG00000131773 KH RNA binding domain containing, signal transduction associated 3 8 135457457-135656722 Predicted intracellular proteins Evidence at protein level HPA000275, HPA000500, HPA000981 Enhanced Supported Nucleoplasm Renal cancer:7.16e-6 (favourable) Expressed in all Group enriched 7 cerebral cortex: 89.1;testis: 285.9 epididymis: 27.8 Cell line enhanced WM-115: 83.8 +CHD1L ALC1 ENSG00000131778 Chromodomain helicase DNA binding protein 1 like 1 147242641-147295766 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027789, HPA028670 Enhanced Supported Nucleoplasm Renal cancer:1.31e-9 (unfavourable), Liver cancer:3.07e-4 (unfavourable) Expressed in all Expressed in all testis: 48.4 Expressed in all +PEX11B ENSG00000131779 Peroxisomal biogenesis factor 11 beta 1 145911350-145918837 Disease related genes, Predicted membrane proteins Evidence at protein level HPA050104 Supported Liver cancer:2.67e-4 (unfavourable), Lung cancer:6.85e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 44.8 Expressed in all +FMO5 ENSG00000131781 Flavin containing monooxygenase 5 1 147175351-147243050 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012373 Enhanced Supported Endoplasmic reticulum
Cytosol Renal cancer:1.34e-6 (favourable) Tissue enriched Tissue enhanced liver: 324.7 small intestine: 75.4 Cell line enhanced Hep G2: 26.6;HMC-1: 7.7;THP-1: 6.7 +PIAS3 FLJ14651, ZMIZ5 ENSG00000131788 Protein inhibitor of activated STAT 3 1 145848522-145859836 Predicted intracellular proteins Evidence at protein level HPA006389, HPA067383 Approved Supported Nucleoplasm Renal cancer:1.21e-7 (unfavourable), Liver cancer:6.12e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 60.1 Expressed in all +PRKAB2 ENSG00000131791 Protein kinase AMP-activated non-catalytic subunit beta 2 1 147155106-147172550 Predicted intracellular proteins Evidence at protein level HPA044342 Approved Approved Nucleoplasm Thyroid cancer:6.78e-7 (unfavourable), Breast cancer:4.55e-4 (unfavourable), Head and neck cancer:7.32e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 45.5 Expressed in all +FSHB ENSG00000131808 Follicle stimulating hormone beta subunit 11 30231016-30235261 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level CAB023410, HPA069703 Supported Not detected Not detected all non-specific tissues: 0.0 Not detected +PDHA1 PDHA ENSG00000131828 Pyruvate dehydrogenase (lipoamide) alpha 1 X 19343893-19361705 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA047487, HPA047864, HPA063053 Approved Supported Mitochondria Renal cancer:1.13e-7 (favourable) Expressed in all Expressed in all heart muscle: 222.0 Expressed in all +RAI2 ENSG00000131831 Retinoic acid induced 2 X 17800049-17861337 Predicted intracellular proteins Evidence at protein level HPA051054 Uncertain Approved Plasma membrane Renal cancer:3.39e-14 (favourable), Pancreatic cancer:2.77e-4 (favourable) Expressed in all Mixed fallopian tube: 79.1 Cell line enriched 9 ASC diff: 71.0 +MCCC2 MCCB ENSG00000131844 Methylcrotonoyl-CoA carboxylase 2 5 71587288-71658704 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038300, HPA038301, HPA061546 Enhanced Enhanced Mitochondria Renal cancer:6.43e-8 (favourable), Liver cancer:1.70e-4 (favourable), Colorectal cancer:3.62e-4 (favourable) Expressed in all Expressed in all prostate: 77.2 Mixed +ZNF304 ENSG00000131845 Zinc finger protein 304 19 57351307-57359898 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050531 Approved Approved Nuclear speckles Renal cancer:1.52e-7 (favourable), Melanoma:4.95e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 15.9 Mixed +ZSCAN5A MGC4161, ZNF495, ZSCAN5 ENSG00000131848 Zinc finger and SCAN domain containing 5A 19 56219670-56368383 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041263, HPA043123, HPA046836, HPA060667 Uncertain Uncertain Nuclear speckles Mixed Tissue enhanced testis: 34.6 fallopian tube: 11.4 Expressed in all +ZNF132 pHZ-12 ENSG00000131849 Zinc finger protein 132 19 58432814-58440222 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA008726 Uncertain Approved Vesicles
Intermediate filaments Renal cancer:7.26e-13 (favourable), Pancreatic cancer:1.92e-4 (favourable) Mixed Mixed parathyroid gland: 11.6 Mixed +USP29 ENSG00000131864 Ubiquitin specific peptidase 29 19 57119138-57131926 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021064 Uncertain Not detected Tissue enriched 5 testis: 9.0 skin: 1.7 Not detected +SELENOS AD-015, MGC2553, SBBI8, SELS, SEPS1, VIMP ENSG00000131871 Selenoprotein S 15 101270817-101277500 Predicted membrane proteins Evidence at protein level HPA010025 Approved Enhanced Endoplasmic reticulum Endometrial cancer:1.33e-4 (favourable), Ovarian cancer:5.19e-4 (favourable) Expressed in all Expressed in all testis: 141.8 Expressed in all +CHSY1 CSS1, KIAA0990 ENSG00000131873 Chondroitin sulfate synthase 1 15 101175723-101251932 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA048902 Uncertain Renal cancer:6.33e-5 (unfavourable) Expressed in all Expressed in all placenta: 64.8 Expressed in all +SNRPA1 Lea1 ENSG00000131876 Small nuclear ribonucleoprotein polypeptide A' 15 101281510-101295282 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045622, HPA048499 Supported Supported Nucleoplasm
Nuclear speckles
Nuclear bodies Renal cancer:0.00e+0 (unfavourable), Liver cancer:8.56e-5 (unfavourable), Ovarian cancer:8.83e-5 (favourable) Expressed in all Expressed in all testis: 68.6 Expressed in all +LLGL1 DLG4, HUGL, HUGL-1, Lgl1, LLGL, Mgl1 ENSG00000131899 LLGL1, scribble cell polarity complex component 17 18225587-18244875 Predicted intracellular proteins Evidence at protein level HPA022924, HPA023569 Enhanced Liver cancer:2.72e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 21.1 endometrium: 7.0 Expressed in all +NR0B2 SHP ENSG00000131910 Nuclear receptor subfamily 0 group B member 2 1 26911489-26913966 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Group enriched Tissue enhanced duodenum: 78.6;liver: 48.8 small intestine: 28.9 Cell line enriched 19 Hep G2: 53.5 +LIN28A CSDD1, FLJ12457, LIN-28, LIN28, ZCCHC1 ENSG00000131914 Lin-28 homolog A 1 26410778-26429722 Predicted intracellular proteins Evidence at protein level CAB020785 Enhanced Uncertain Nucleoplasm Tissue enriched Tissue enriched 12 testis: 4.3 skin: 0.3 Cell line enriched 10 NTERA-2: 860.9 +THAP1 4833431A01Rik, DYT6, FLJ10477 ENSG00000131931 THAP domain containing 1 8 42836674-42843325 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071310 Supported Nucleus Expressed in all Mixed testis: 17.6 Expressed in all +RHPN2 ENSG00000131941 Rhophilin Rho GTPase binding protein 2 19 32978593-33064888 Predicted intracellular proteins Evidence at protein level HPA051749 Uncertain Renal cancer:1.22e-8 (favourable), Head and neck cancer:1.58e-4 (unfavourable) Expressed in all Mixed prostate: 43.6 Mixed +C19orf12 DKFZP762D096, MGC10922, MPAN, NBIA4, SPG43 ENSG00000131943 Chromosome 19 open reading frame 12 19 29698886-29715789 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046930 Approved Expressed in all Expressed in all adipose tissue: 122.7 Expressed in all +FAAP24 C19orf40, FLJ46828, MGC32020 ENSG00000131944 Fanconi anemia core complex associated protein 24 19 32972209-32978222 Predicted intracellular proteins Evidence at protein level HPA041168 Uncertain Supported Nucleoplasm
Vesicles Renal cancer:4.00e-7 (unfavourable), Endometrial cancer:4.38e-4 (unfavourable) Expressed in all Mixed testis: 11.9 Expressed in all +LRRC9 FLJ46156 ENSG00000131951 Leucine rich repeat containing 9 14 59919713-60063559 Predicted intracellular proteins Evidence at transcript level HPA040965, HPA041381 Uncertain Not detected Tissue enhanced parathyroid gland: 3.5;testis: 10.8 fallopian tube: 1.9 Cell line enhanced NTERA-2: 1.0 +ACTR10 ACTR11, Arp10, Arp11, HARP11 ENSG00000131966 Actin-related protein 10 homolog 14 58200080-58235636 Predicted intracellular proteins Evidence at protein level HPA071251 Supported Nucleoli Renal cancer:8.48e-8 (favourable), Liver cancer:2.71e-5 (unfavourable), Breast cancer:3.24e-4 (unfavourable) Expressed in all Mixed adipose tissue: 11.7 Expressed in all +ABHD12B BEM46L3, C14orf29 ENSG00000131969 Abhydrolase domain containing 12B 14 50872160-50904970 Predicted intracellular proteins Evidence at transcript level HPA002873 Uncertain Uncertain Nucleus Tissue enriched Tissue enriched 8 skin: 16.3 cerebral cortex: 2.1 Not detected +GCH1 DYT14, DYT5, DYT5a, GCH, GTPCH1 ENSG00000131979 GTP cyclohydrolase 1 14 54842008-54902852 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028612 Approved Supported Nucleoplasm
Nuclear membrane
Cytosol Pancreatic cancer:1.41e-4 (favourable), Urothelial cancer:6.67e-4 (favourable), Ovarian cancer:8.69e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 22.6 liver: 18.8 Cell line enhanced SH-SY5Y: 48.2 +LGALS3 GALIG, LGALS2, MAC-2 ENSG00000131981 Galectin 3 14 55124110-55145413 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003162, CAB005191 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all colon: 871.1 Cell line enhanced SK-MEL-30: 1368.8 +PODNL1 FLJ23447, SLRR5B ENSG00000132000 Podocan like 1 19 13931187-13953392 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042807 Approved Glioma:2.06e-8 (unfavourable), Urothelial cancer:4.49e-4 (unfavourable) Mixed Tissue enhanced placenta: 12.3 skin: 8.5 Cell line enhanced HSkMC: 17.5;SiHa: 21.2;U-2 OS: 16.8 +DNAJB1 Hsp40, HSPF1, RSPH16B, Sis1 ENSG00000132002 DnaJ heat shock protein family (Hsp40) member B1 19 14514770-14529770 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB017450, HPA063247 Enhanced Enhanced Nucleus
Cytosol Renal cancer:5.96e-4 (favourable) Expressed in all Expressed in all adrenal gland: 348.8 Expressed in all +ZSWIM4 FLJ12221 ENSG00000132003 Zinc finger SWIM-type containing 4 19 13795460-13832230 Plasma proteins, Predicted intracellular proteins Evidence at transcript level HPA042084 Uncertain Renal cancer:7.85e-5 (unfavourable) Expressed in all Mixed appendix: 5.7 Mixed +FBXW9 Fbw9, MGC10870 ENSG00000132004 F-box and WD repeat domain containing 9 19 12688053-12696643 Predicted intracellular proteins Evidence at protein level HPA042087 Approved Approved Cytosol Expressed in all Mixed fallopian tube: 21.0 Expressed in all +RFX1 EF-C ENSG00000132005 Regulatory factor X1 19 13961538-14007039 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048722 Approved Supported Nucleoplasm Head and neck cancer:2.42e-4 (favourable), Pancreatic cancer:4.92e-4 (favourable) Expressed in all Expressed in all testis: 16.8 Expressed in all +ZNF20 KOX13 ENSG00000132010 Zinc finger protein 20 19 12092843-12140407 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020887 Uncertain Approved Nucleoplasm
Plasma membrane Not detected Mixed testis: 9.3 Mixed +C19orf57 MGC11271 ENSG00000132016 Chromosome 19 open reading frame 57 19 13882348-13906452 Predicted intracellular proteins Evidence at protein level HPA044012, HPA054615 Enhanced Approved Nucleoplasm Endometrial cancer:3.38e-4 (unfavourable), Head and neck cancer:5.14e-4 (favourable) Mixed Tissue enhanced testis: 20.7 skin: 13.9 Mixed +DCAF15 C19orf72, MGC99481 ENSG00000132017 DDB1 and CUL4 associated factor 15 19 13952492-13961449 Predicted intracellular proteins Evidence at protein level HPA068351 Approved Vesicles
Mitochondria Renal cancer:1.34e-5 (unfavourable), Pancreatic cancer:7.97e-4 (favourable) Expressed in all Expressed in all testis: 59.9 Expressed in all +CC2D1A FLJ20241, MRT3 ENSG00000132024 Coiled-coil and C2 domain containing 1A 19 13906201-13930879 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005436, CAB015220 Supported Supported Nucleoli fibrillar center
Plasma membrane
Cytosol Head and neck cancer:7.02e-4 (favourable) Expressed in all Expressed in all duodenum: 35.6 Expressed in all +RTBDN FLJ36353 ENSG00000132026 Retbindin 19 12825478-12835428 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA052511 Approved Endoplasmic reticulum Mixed Group enriched 6 adrenal gland: 4.6;cerebral cortex: 14.6;testis: 3.5 stomach: 1.2 Cell line enhanced SCLC-21H: 9.8;SH-SY5Y: 5.8;U-266/84: 16.0 +MATN3 EDM5, HOA ENSG00000132031 Matrilin 3 2 19992111-20012694 Disease related genes, Predicted secreted proteins Evidence at protein level HPA051250 Approved Endoplasmic reticulum
Golgi apparatus Stomach cancer:4.74e-5 (unfavourable), Liver cancer:8.62e-5 (unfavourable), Cervical cancer:1.41e-4 (unfavourable) Expressed in all Tissue enhanced lung: 20.2;placenta: 16.5 seminal vesicle: 6.2 Cell line enriched 5 Hep G2: 98.9 +TRIM21 RNF81, Ro/SSA, RO52, SSA1 ENSG00000132109 Tripartite motif containing 21 11 4384897-4393696 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004566, HPA005673 Approved Approved Nucleoplasm Thyroid cancer:2.26e-6 (favourable), Breast cancer:4.83e-5 (favourable), Liver cancer:1.87e-4 (unfavourable) Expressed in all Expressed in all spleen: 41.2 Mixed +SPATA6 FLJ10007, SRF-1, SRF1 ENSG00000132122 Spermatogenesis associated 6 1 48295372-48472208 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA028234 Approved Nucleoplasm
Golgi apparatus
Vesicles Mixed Tissue enhanced testis: 89.0 fallopian tube: 24.6 Cell line enhanced ASC TERT1: 14.7 +LRRC41 MUF1 ENSG00000132128 Leucine rich repeat containing 41 1 46261196-46303608 Predicted intracellular proteins Evidence at protein level HPA051941 Uncertain Approved Nucleoplasm
Nuclear bodies Liver cancer:1.66e-9 (unfavourable), Cervical cancer:5.50e-4 (unfavourable), Renal cancer:6.34e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 69.8 Expressed in all +CCT6B Cctz2, TSA303 ENSG00000132141 Chaperonin containing TCP1 subunit 6B 17 34927859-34981078 Predicted intracellular proteins Evidence at protein level HPA042996, HPA045576, HPA049949 Uncertain Approved Cytosol Mixed Tissue enriched 33 testis: 225.1 breast: 6.9 Cell line enhanced RPMI-8226: 8.3 +DHX30 DDX30, FLJ11214, KIAA0890 ENSG00000132153 DExH-box helicase 30 3 47802909-47850195 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA034806 Supported Supported Mitochondria
Cytosol Renal cancer:1.37e-6 (favourable) Expressed in all Expressed in all testis: 46.2 Expressed in all +RAF1 c-Raf, CRAF, Raf-1 ENSG00000132155 Raf-1 proto-oncogene, serine/threonine kinase 3 12583601-12664226 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA002640, CAB019291 Approved Approved Nuclear speckles Expressed in all Expressed in all parathyroid gland: 100.7 Expressed in all +SLC6A11 GAT3 ENSG00000132164 Solute carrier family 6 member 11 3 10816200-10940733 Predicted membrane proteins, Transporters Evidence at protein level HPA037981 Supported Supported Tissue enhanced Tissue enhanced cerebral cortex: 18.1;skin: 6.7 esophagus: 5.5 Cell line enhanced HaCaT: 11.8;Hep G2: 10.7;hTCEpi: 8.5;NTERA-2: 6.6 +PPARG NR1C3, PPARG1, PPARG2, PPARgamma ENSG00000132170 Peroxisome proliferator activated receptor gamma 3 12287368-12434356 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004282, HPA051239, HPA063663 Approved Enhanced Nucleus
Vesicles Renal cancer:1.59e-8 (favourable), Liver cancer:3.41e-5 (unfavourable), Urothelial cancer:5.52e-5 (favourable) Expressed in all Tissue enhanced adipose tissue: 173.3 placenta: 59.2 Cell line enhanced ASC diff: 131.6;BEWO: 223.4;RT4: 116.1 +NUP210 FLJ22389, GP210, KIAA0906, POM210 ENSG00000132182 Nucleoporin 210 3 13316235-13420309 Predicted membrane proteins, Transporters Evidence at protein level HPA066888 Approved Liver cancer:6.03e-6 (unfavourable) Expressed in all Expressed in all lymph node: 48.6 Mixed +FCRLA FCRL, FCRLa, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRLM1, FCRLX, FREB, MGC4595 ENSG00000132185 Fc receptor like A 1 161706972-161714352 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB016545 Enhanced Tissue enriched Group enriched 10 appendix: 31.2;lymph node: 80.5;spleen: 56.4;tonsil: 86.7 urinary bladder: 6.2 Cell line enhanced Daudi: 338.0;SK-MEL-30: 150.5;U-698: 179.6 +HSD17B7 PRAP, SDR37C1 ENSG00000132196 Hydroxysteroid 17-beta dehydrogenase 7 1 162790702-162812817 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA047496 Approved Renal cancer:8.47e-5 (unfavourable) Expressed in all Mixed liver: 16.9 Expressed in all +ENOSF1 HSRTSBETA, rTS, TYMSAS ENSG00000132199 Enolase superfamily member 1 18 670324-712676 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047829 Enhanced Breast cancer:2.27e-4 (favourable) Expressed in all Mixed kidney: 38.9 Expressed in all +EMILIN2 FLJ33200, FOAP-10 ENSG00000132205 Elastin microfibril interfacer 2 18 2847030-2915993 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA064576 Supported Renal cancer:1.62e-4 (unfavourable), Liver cancer:6.30e-4 (unfavourable) Expressed in all Tissue enriched 9 parathyroid gland: 269.3 placenta: 31.4 Cell line enhanced ASC diff: 33.3;BEWO: 36.7;HL-60: 30.1;HMC-1: 53.5;U-2197: 43.7 +SLX1A GIYD1 ENSG00000132207 SLX1 homolog A, structure-specific endonuclease subunit 16 30193887-30197561 Predicted intracellular proteins Evidence at protein level HPA047038 Uncertain Approved Nucleoplasm Not detected Expressed in all duodenum: 50.3 Mixed +ARFIP2 POR1 ENSG00000132254 ADP ribosylation factor interacting protein 2 11 6474683-6481479 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB032985, HPA038156 Approved Approved Nucleus
Nucleoli fibrillar center
Golgi apparatus Endometrial cancer:2.00e-5 (favourable), Renal cancer:9.53e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 82.5 Expressed in all +TRIM5 RNF88, TRIM5alpha ENSG00000132256 Tripartite motif containing 5 11 5663557-5938619 Enzymes, Predicted intracellular proteins Evidence at protein level CAB013497, HPA023420, HPA023422 Approved Supported Cytosol Expressed in all Mixed epididymis: 26.9 Expressed in all +CNGA4 CNCA2, CNG5, CNGB2, OCNC2, OCNCb ENSG00000132259 Cyclic nucleotide gated channel alpha 4 11 6234765-6244429 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Endometrial cancer:1.48e-4 (favourable) Tissue enriched Group enriched 9 fallopian tube: 27.9;testis: 10.5 lung: 2.1 Not detected +TRIM22 GPSTAF50, RNF94, STAF50 ENSG00000132274 Tripartite motif containing 22 11 5689689-5737089 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003307, HPA003575 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all spleen: 174.9 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 183.3 +RRP8 KIAA0409, NML ENSG00000132275 Ribosomal RNA processing 8, methyltransferase, homolog (yeast) 11 6595075-6603620 Predicted intracellular proteins Evidence at protein level HPA038487, HPA057562 Supported Supported Nucleus
Nucleoli
Cytosol Liver cancer:3.10e-7 (unfavourable) Expressed in all Expressed in all seminal vesicle: 12.4 Expressed in all +TIMM10B FXC1, TIM10B, Tim9b ENSG00000132286 Translocase of inner mitochondrial membrane 10B 11 6481447-6484679 Predicted intracellular proteins Evidence at protein level HPA052265 Approved Renal cancer:3.19e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 52.8 Expressed in all +EFR3A KIAA0143 ENSG00000132294 EFR3 homolog A 8 131904088-132013642 Predicted intracellular proteins Evidence at protein level HPA022859, HPA023092, HPA023402 Enhanced Supported Plasma membrane
Cytosol Expressed in all Expressed in all cerebral cortex: 70.4 Expressed in all +HHLA1 PLA2L ENSG00000132297 HERV-H LTR-associating 1 8 132061486-132111159 Predicted secreted proteins Evidence at transcript level HPA059051 Uncertain Not detected Not detected placenta: 0.1 Cell line enriched 12 NTERA-2: 1.1 +PTCD3 DKFZp666K071, FLJ20758 ENSG00000132300 Pentatricopeptide repeat domain 3 2 86106182-86142157 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA041154, HPA041382 Supported Enhanced Mitochondria Stomach cancer:6.77e-4 (favourable), Urothelial cancer:6.86e-4 (favourable) Expressed in all Expressed in all testis: 31.2 Expressed in all +IMMT HMP, Mic60, MINOS2, P87, P89 ENSG00000132305 Inner membrane mitochondrial protein 2 86143932-86195770 Predicted intracellular proteins Evidence at protein level CAB022439, HPA036164, HPA036165 Enhanced Enhanced Mitochondria Renal cancer:3.51e-6 (favourable), Endometrial cancer:1.06e-4 (unfavourable), Liver cancer:2.03e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 107.3 Expressed in all +MRPL35 ENSG00000132313 Mitochondrial ribosomal protein L35 2 86199355-86213794 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA043482 Uncertain Renal cancer:9.96e-6 (favourable), Liver cancer:3.51e-4 (unfavourable) Expressed in all Expressed in all rectum: 64.6 Expressed in all +IQCA1 DRC11, FLJ22527, IQCA ENSG00000132321 IQ motif containing with AAA domain 1 2 236324147-236507542 Predicted intracellular proteins Evidence at transcript level HPA057320 Uncertain Nucleus Renal cancer:2.54e-4 (favourable) Tissue enhanced Tissue enhanced fallopian tube: 17.9;thyroid gland: 32.3 cerebral cortex: 11.4 Cell line enhanced EFO-21: 3.1;HBEC3-KT: 2.2;HeLa: 2.5;U-2 OS: 12.9 +ILKAP DKFZP434J2031, FLJ10181, PPM1O ENSG00000132323 ILK associated serine/threonine phosphatase 2 238170401-238203729 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004752, HPA056099 Uncertain Approved Nucleoplasm Renal cancer:9.89e-6 (unfavourable), Liver cancer:1.04e-4 (unfavourable) Expressed in all Expressed in all testis: 28.0 Expressed in all +PER2 KIAA0347 ENSG00000132326 Period circadian clock 2 2 238244038-238290102 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA060510 Enhanced Head and neck cancer:2.29e-4 (favourable) Expressed in all Expressed in all testis: 22.2 Mixed +RAMP1 ENSG00000132329 Receptor activity modifying protein 1 2 237858893-237912114 FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA057814 Supported Nucleoplasm
Nuclear membrane Stomach cancer:1.68e-4 (unfavourable), Liver cancer:7.61e-4 (favourable) Expressed in all Tissue enhanced endometrium: 234.1 smooth muscle: 171.5 Cell line enhanced HDLM-2: 126.9;PC-3: 142.8;SH-SY5Y: 202.6 +SCLY SCL ENSG00000132330 Selenocysteine lyase 2 238060889-238099413 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055760 Uncertain Approved Golgi apparatus Not detected Expressed in all testis: 12.9 Expressed in all +PTPRE PTPE ENSG00000132334 Protein tyrosine phosphatase, receptor type E 10 127907061-128085855 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015870, HPA021872 Supported Approved Intermediate filaments Renal cancer:4.08e-5 (unfavourable) Expressed in all Mixed appendix: 34.8 Cell line enhanced HUVEC TERT2: 34.9;TIME: 64.9 +RAN ARA24, Gsp1, TC4 ENSG00000132341 RAN, member RAS oncogene family 12 130871879-130877678 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA063353 Uncertain Nucleus Liver cancer:9.99e-8 (unfavourable), Renal cancer:1.46e-7 (unfavourable), Prostate cancer:7.86e-5 (unfavourable) Expressed in all Expressed in all testis: 559.9 Expressed in all +PRKAA1 AMPKa1 ENSG00000132356 Protein kinase AMP-activated catalytic subunit alpha 1 5 40759379-40798374 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB005050, HPA035409, HPA064946 Supported Supported Nuclear speckles Expressed in all Expressed in all testis: 74.4 Expressed in all +CARD6 CINCIN1 ENSG00000132357 Caspase recruitment domain family member 6 5 40841184-40860175 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036438 Uncertain Approved Focal adhesion sites
Cytosol Expressed in all Mixed spleen: 17.0 Cell line enhanced HUVEC TERT2: 26.1;TIME: 27.4 +RAP1GAP2 GARNL4, KIAA1039 ENSG00000132359 RAP1 GTPase activating protein 2 17 2755705-3037739 Predicted intracellular proteins Evidence at protein level HPA022148, HPA022896 Approved Supported Nuclear membrane
Cytosol Renal cancer:1.36e-6 (favourable) Expressed in all Mixed cerebral cortex: 35.2 Cell line enhanced SH-SY5Y: 55.4 +CLUH CLU1, KIAA0664 ENSG00000132361 Clustered mitochondria homolog 17 2689386-2712663 Predicted intracellular proteins Evidence at protein level HPA031505, HPA044346 Uncertain Supported Nuclear bodies
Vesicles Renal cancer:1.92e-5 (favourable) Expressed in all Expressed in all esophagus: 50.7 Expressed in all +INPP5K SKIP ENSG00000132376 Inositol polyphosphate-5-phosphatase K 17 1494571-1516888 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031044 Uncertain Pancreatic cancer:1.47e-6 (favourable), Endometrial cancer:2.33e-5 (favourable), Cervical cancer:3.91e-4 (favourable) Expressed in all Expressed in all adipose tissue: 32.2 Expressed in all +MYBBP1A FLJ37886, P160, PAP2 ENSG00000132382 MYB binding protein 1a 17 4538897-4555631 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005466 Supported Supported Nucleoli
Vesicles Pancreatic cancer:1.61e-4 (favourable), Renal cancer:5.95e-4 (unfavourable), Thyroid cancer:8.12e-4 (unfavourable), Melanoma:8.47e-4 (unfavourable) Expressed in all Expressed in all skin: 21.6 Expressed in all +RPA1 HSSB, REPA1, RF-A, RP-A, RPA70 ENSG00000132383 Replication protein A1 17 1829702-1900082 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004563, HPA006914, HPA046497 Supported Enhanced Nucleoplasm Liver cancer:9.00e-9 (unfavourable) Expressed in all Expressed in all fallopian tube: 44.7 Expressed in all +SERPINF1 EPC-1, PEDF, PIG35 ENSG00000132386 Serpin family F member 1 17 1761959-1777574 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005825 Approved Renal cancer:1.40e-8 (unfavourable), Cervical cancer:5.49e-4 (favourable) Expressed in all Expressed in all gallbladder: 739.1 Cell line enhanced ASC diff: 752.1;ASC TERT1: 594.5;Hep G2: 362.7;HHSteC: 306.9;HSkMC: 845.8 +UBE2G1 UBC7, UBE2G ENSG00000132388 Ubiquitin conjugating enzyme E2 G1 17 4269259-4366628 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045681, HPA050551 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all skeletal muscle: 73.2 Expressed in all +EEFSEC eEFSec, EFSEC, SELB ENSG00000132394 Eukaryotic elongation factor, selenocysteine-tRNA specific 3 128153454-128408646 Predicted intracellular proteins Evidence at protein level HPA035795 Approved Approved Nucleus
Nuclear bodies
Cytosol Cervical cancer:2.98e-5 (favourable) Expressed in all Expressed in all testis: 18.8 Expressed in all +TBC1D14 KIAA1322 ENSG00000132405 TBC1 domain family member 14 4 6909242-7033118 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036930, HPA067398 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:5.28e-10 (favourable) Expressed in all Expressed in all cerebral cortex: 67.5 Expressed in all +TMEM128 MGC13159 ENSG00000132406 Transmembrane protein 128 4 4235542-4248212 Predicted membrane proteins, Transporters Evidence at protein level HPA044809 Uncertain Expressed in all Expressed in all thyroid gland: 63.9 Expressed in all +COQ3 bA9819.1 ENSG00000132423 Coenzyme Q3, methyltransferase 6 99369400-99394204 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031273, HPA031274 Enhanced Approved Nucleoplasm
Mitochondria Renal cancer:6.86e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 20.8 Expressed in all +PNISR bA98I9.2, C6orf111, DKFZp564B0769, FLJ14752, SFRS18, SRrp130 ENSG00000132424 PNN interacting serine and arginine rich protein 6 99398051-99425331 Predicted intracellular proteins Evidence at protein level HPA038796 Uncertain Supported Nuclear speckles
Cytosol Urothelial cancer:1.09e-4 (favourable), Renal cancer:1.41e-4 (unfavourable), Pancreatic cancer:5.27e-4 (favourable) Expressed in all Expressed in all endometrium: 127.1 Expressed in all +POPDC3 bA355M14.1, MGC22671, POP3 ENSG00000132429 Popeye domain containing 3 6 105158280-105179995 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012514 Approved Nucleoli
Cytosol Head and neck cancer:4.43e-4 (unfavourable), Lung cancer:5.79e-4 (unfavourable) Mixed Group enriched 7 cerebral cortex: 8.8;heart muscle: 19.8;skeletal muscle: 41.8;testis: 9.1 epididymis: 2.9 Cell line enhanced RH-30: 20.5 +SEC61G SSS1 ENSG00000132432 Sec61 translocon gamma subunit 7 54752250-54759974 Predicted membrane proteins, Transporters Evidence at protein level HPA053196 Uncertain Renal cancer:6.60e-8 (unfavourable), Head and neck cancer:4.64e-7 (unfavourable), Liver cancer:3.85e-6 (unfavourable) Expressed in all Expressed in all epididymis: 408.8 Expressed in all +LANCL2 GPR69B, TASP ENSG00000132434 LanC like 2 7 55365448-55433742 Predicted intracellular proteins Evidence at protein level HPA019711, HPA029535 Uncertain Supported Nucleus
Cytosol Renal cancer:1.03e-6 (favourable), Ovarian cancer:1.89e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 41.2 parathyroid gland: 16.5 Cell line enriched 6 A-431: 130.0 +FIGNL1 ENSG00000132436 Fidgetin like 1 7 50444128-50542535 Predicted intracellular proteins Evidence at protein level HPA055542 Approved Renal cancer:9.54e-7 (unfavourable), Liver cancer:1.01e-4 (unfavourable), Melanoma:4.82e-4 (unfavourable) Expressed in all Mixed smooth muscle: 14.7 Mixed +DDC AADC ENSG00000132437 Dopa decarboxylase 7 50458436-50565457 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA017742 Enhanced Approved Actin filaments Mixed Tissue enhanced duodenum: 155.2;kidney: 320.9;small intestine: 180.5 adrenal gland: 63.8 Group enriched 9 CACO-2: 44.3;Hep G2: 32.3;SCLC-21H: 154.0;SH-SY5Y: 144.1 +FTHL17 CT38 ENSG00000132446 Ferritin heavy chain like 17 X 31071241-31072053 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enriched 14 testis: 3.4 skin: 0.2 Not detected +GRSF1 ENSG00000132463 G-rich RNA sequence binding factor 1 4 70815782-70839945 Predicted intracellular proteins Evidence at protein level HPA036984, HPA036985 Enhanced Enhanced Mitochondria Renal cancer:2.72e-9 (favourable), Colorectal cancer:1.47e-5 (favourable), Liver cancer:8.29e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 95.7 Expressed in all +ENAM AIH2 ENSG00000132464 Enamelin 4 70628744-70686816 Disease related genes, Predicted secreted proteins Evidence at protein level Renal cancer:1.81e-14 (favourable) Tissue enhanced Tissue enhanced epididymis: 8.3;kidney: 5.9 heart muscle: 2.4 Not detected +JCHAIN IGCJ, IGJ, JCH ENSG00000132465 Joining chain of multimeric IgA and IgM 4 70655541-70681817 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB034436, HPA044132 Enhanced Head and neck cancer:7.56e-7 (favourable), Breast cancer:1.81e-6 (favourable), Renal cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all colon: 6965.1 Group enriched 205 Daudi: 2569.0;Karpas-707: 1336.5;RPMI-8226: 2653.0;U-266/70: 5934.2;U-266/84: 2263.1;U-698: 3199.2 +ANKRD17 FLJ22206, GTAR, KIAA0697, MASK2, NY-BR-16 ENSG00000132466 Ankyrin repeat domain 17 4 73073376-73258798 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045024, HPA063731 Approved Supported Nucleus
Nuclear membrane Expressed in all Expressed in all parathyroid gland: 49.7 Expressed in all +UTP3 CRLZ1, DKFZp761F222, FLJ23256, SAS10 ENSG00000132467 UTP3, small subunit processome component homolog (S. cerevisiae) 4 70688479-70690551 Predicted intracellular proteins Evidence at protein level HPA035655, HPA041453 Approved Supported Nucleoli
Vesicles Renal cancer:3.16e-4 (favourable) Expressed in all Expressed in all spleen: 43.2 Expressed in all +ITGB4 CD104 ENSG00000132470 Integrin subunit beta 4 17 75721328-75757818 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002422, CAB005258, HPA036348, HPA036349 Enhanced Supported Plasma membrane
Cell Junctions Pancreatic cancer:6.39e-4 (unfavourable), Lung cancer:7.18e-4 (unfavourable) Expressed in all Mixed skin: 84.3 Cell line enhanced CAPAN-2: 787.0;HaCaT: 304.0;HBEC3-KT: 550.4 +WBP2 GRAMD6, WBP-2 ENSG00000132471 WW domain binding protein 2 17 75845699-75856507 Predicted intracellular proteins Evidence at protein level HPA065682, HPA068819 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 360.8 Expressed in all +H3F3B H3.3B ENSG00000132475 H3 histone family member 3B 17 75776434-75785893 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB037166, CAB037187, CAB037221, HPA042570 Supported Enhanced Nucleoplasm Expressed in all Expressed in all bone marrow: 2832.4 Expressed in all +UNK KIAA1753, ZC3H5, ZC3HDC5 ENSG00000132478 Unkempt family zinc finger 17 75784771-75825799 Predicted intracellular proteins Evidence at protein level HPA023636, HPA027962 Uncertain Supported Cytosol
Cytoplasmic bodies Pancreatic cancer:6.58e-5 (favourable), Head and neck cancer:2.02e-4 (favourable) Expressed in all Expressed in all skin: 16.4 Expressed in all +TRIM47 GOA, RNF100 ENSG00000132481 Tripartite motif containing 47 17 75874161-75878575 Predicted intracellular proteins Evidence at protein level HPA014933 Uncertain Supported Cytosol Liver cancer:5.59e-5 (unfavourable), Renal cancer:9.69e-5 (unfavourable), Breast cancer:6.54e-4 (favourable) Expressed in all Mixed cerebral cortex: 23.8 Mixed +ZRANB2 ZIS, ZIS1, ZIS2, ZNF265 ENSG00000132485 Zinc finger RANBP2-type containing 2 1 71063291-71081297 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053960, HPA061949, HPA063298 Supported Enhanced Nucleus Renal cancer:1.57e-8 (unfavourable), Liver cancer:7.29e-5 (unfavourable), Prostate cancer:5.70e-4 (unfavourable) Expressed in all Expressed in all endometrium: 116.1 Expressed in all +EIF5A EIF-5A, EIF5A1, MGC104255, MGC99547 ENSG00000132507 Eukaryotic translation initiation factor 5A 17 7306999-7312463 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB005042, HPA061298 Approved Enhanced Nucleoplasm
Cytosol Renal cancer:1.63e-5 (unfavourable), Lung cancer:9.04e-4 (unfavourable) Expressed in all Expressed in all esophagus: 435.8 Expressed in all +KDM6B JMJD3, KIAA0346 ENSG00000132510 Lysine demethylase 6B 17 7839904-7854796 Predicted intracellular proteins Evidence at protein level HPA037988 Enhanced Approved Nuclear speckles Thyroid cancer:3.37e-4 (unfavourable), Renal cancer:6.07e-4 (favourable) Expressed in all Expressed in all appendix: 28.8 Mixed +CLEC10A CD301, CLECSF13, CLECSF14, HML, HML2 ENSG00000132514 C-type lectin domain family 10 member A 17 7074537-7080307 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA021937 Approved Head and neck cancer:1.26e-5 (favourable), Testis cancer:4.22e-4 (unfavourable), Lung cancer:9.24e-4 (favourable) Expressed in all Mixed appendix: 38.9 Not detected +SLC52A1 FLJ10060, GPCR42, GPR172B, hRFT1, PAR2, RFVT1 ENSG00000132517 Solute carrier family 52 member 1 17 5032600-5052009 Disease related genes, Predicted membrane proteins Evidence at protein level CAB011449 Uncertain Cervical cancer:9.54e-4 (favourable) Mixed Group enriched 10 duodenum: 36.1;placenta: 26.1;skin: 13.2;small intestine: 26.3 parathyroid gland: 2.6 Cell line enhanced A549: 2.1;BEWO: 1.9;HMC-1: 4.1;SK-BR-3: 2.0 +GUCY2D CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, retGC, RETGC-1, ROS-GC1 ENSG00000132518 Guanylate cyclase 2D, retinal 17 8002594-8020339 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Mixed Tissue enhanced testis: 1.4 lymph node: 0.3 Cell line enriched 6 HMC-1: 1.1 +GPS2 ENSG00000132522 G protein pathway suppressor 2 17 7311324-7315564 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA067540 Approved Supported Nucleoplasm Renal cancer:3.42e-5 (unfavourable), Pancreatic cancer:7.50e-5 (favourable) Expressed in all Expressed in all testis: 97.4 Expressed in all +XAF1 BIRC4BP, HSXIAPAF1, XIAPAF1 ENSG00000132530 XIAP associated factor 1 17 6755447-6775647 Predicted intracellular proteins Evidence at protein level HPA057302 Approved Supported Nucleus
Mitochondria
Rods & Rings Renal cancer:2.73e-7 (unfavourable) Expressed in all Mixed spleen: 81.4 Cell line enhanced BJ hTERT+ SV40 Large T+: 69.2;BJ hTERT+ SV40 Large T+ RasG12V: 74.2 +DLG4 PSD-95, PSD95, SAP-90, SAP90 ENSG00000132535 Discs large MAGUK scaffold protein 4 17 7189890-7219702 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB001999, CAB002000, HPA010122 Enhanced Approved Vesicles Pancreatic cancer:8.82e-6 (favourable), Renal cancer:1.70e-4 (unfavourable) Expressed in all Tissue enriched 6 cerebral cortex: 178.6 endometrium: 28.9 Cell line enhanced HMC-1: 57.4 +RIDA HRSP12, P14.5, PSP, UK114 ENSG00000132541 Reactive intermediate imine deaminase A homolog 8 98102344-98117241 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA022856, HPA023489 Enhanced Liver cancer:9.61e-6 (favourable) Expressed in all Group enriched 9 kidney: 454.6;liver: 698.7 cerebral cortex: 62.3 Expressed in all +VPS13B CHS1, COH1 ENSG00000132549 Vacuolar protein sorting 13 homolog B 8 99013266-99877580 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043865 Approved Cell Junctions Expressed in all Mixed parathyroid gland: 14.7 Expressed in all +RGS22 CT145, DKFZP434I092, PRTD-NY2 ENSG00000132554 Regulator of G-protein signaling 22 8 99960936-100131268 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 6 testis: 108.9 fallopian tube: 16.7 Not detected +MATN2 ENSG00000132561 Matrilin 2 8 97868840-98036716 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB033879 Approved Thyroid cancer:9.65e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 456.8 Cell line enhanced BJ hTERT+ SV40 Large T+: 73.2;BJ hTERT+ SV40 Large T+ RasG12V: 104.0;HaCaT: 101.1;HBF TERT88: 97.3 +REEP2 C5orf19, SGC32445, SPG72, Yip2d ENSG00000132563 Receptor accessory protein 2 5 138439017-138446969 Disease related genes, Predicted membrane proteins Evidence at protein level HPA031813 Enhanced Breast cancer:7.83e-5 (favourable), Glioma:3.43e-4 (unfavourable), Melanoma:9.31e-4 (favourable) Tissue enriched Tissue enhanced cerebral cortex: 90.1 smooth muscle: 18.0 Cell line enhanced AN3-CA: 89.1;SCLC-21H: 46.8;SH-SY5Y: 47.6 +PCBD2 DCOH2, DCOHM ENSG00000132570 Pterin-4 alpha-carbinolamine dehydratase 2 5 134904906-135007959 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036428 Uncertain Approved Plasma membrane Expressed in all Expressed in all parathyroid gland: 16.1 Expressed in all +SDF2 ENSG00000132581 Stromal cell derived factor 2 17 28648356-28662189 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042799 Approved Vesicles Liver cancer:1.16e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 27.8 Expressed in all +FLOT2 ECS-1, ECS1, ESA, ESA1, M17S1 ENSG00000132589 Flotillin 2 17 28879335-28897679 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001396, CAB004395 Enhanced Expressed in all Expressed in all spleen: 93.7 Expressed in all +ERAL1 HERA-B ENSG00000132591 Era like 12S mitochondrial rRNA chaperone 1 17 28854938-28861067 Predicted intracellular proteins Evidence at protein level HPA021425, HPA024423 Supported Enhanced Mitochondria
Cytosol Liver cancer:3.59e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 51.2 Expressed in all +PRMT7 FLJ10640, KIAA1933 ENSG00000132600 Protein arginine methyltransferase 7 16 68310974-68358563 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA044241 Supported Supported Nucleoplasm
Nucleoli fibrillar center Endometrial cancer:2.31e-5 (favourable) Expressed in all Expressed in all fallopian tube: 25.0 Expressed in all +NIP7 CGI-37, FLJ10296, HSPC031, KD93 ENSG00000132603 NIP7, nucleolar pre-rRNA processing protein 16 69339430-69343111 Predicted intracellular proteins Evidence at protein level HPA040856, HPA059850 Enhanced Supported Nucleus
Nucleoli Pancreatic cancer:6.69e-5 (unfavourable), Head and neck cancer:1.52e-4 (unfavourable) Expressed in all Expressed in all lymph node: 23.0 Expressed in all +TERF2 TRBF2, TRF2 ENSG00000132604 Telomeric repeat binding factor 2 16 69355561-69408571 Predicted intracellular proteins Evidence at protein level HPA001907, HPA002735, CAB010451 Enhanced Supported Nuclear bodies Expressed in all Expressed in all lymph node: 42.2 Expressed in all +VPS4A FLJ22197, SKD1, SKD1A, SKD2, VPS4, VPS4-1 ENSG00000132612 Vacuolar protein sorting 4 homolog A 16 69311356-69326939 Enzymes, Predicted intracellular proteins Evidence at protein level CAB018751, CAB034411, HPA060092 Approved Renal cancer:1.76e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 31.9 Expressed in all +MTSS1L ABBA, ABBA-1, LOC92154 ENSG00000132613 MTSS1L, I-BAR domain containing 16 70661204-70686066 Predicted intracellular proteins Evidence at protein level HPA048531, HPA066469 Approved Supported Focal adhesion sites Breast cancer:2.85e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 320.2 Mixed +HSPA12B C20orf60, dJ1009E24.2 ENSG00000132622 Heat shock protein family A (Hsp70) member 12B 20 3732667-3753111 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013659, HPA015639 Uncertain Expressed in all Mixed spleen: 25.4 Cell line enhanced CACO-2: 4.0;EFO-21: 4.6;HUVEC TERT2: 7.9;TIME: 4.3 +ANKEF1 ANKRD5, dJ839B4.6, FLJ21669 ENSG00000132623 Ankyrin repeat and EF-hand domain containing 1 20 9986126-10058303 Predicted intracellular proteins Evidence at protein level HPA041151 Approved Approved Nucleoli fibrillar center
Plasma membrane
Cytosol Thyroid cancer:1.58e-4 (unfavourable), Lung cancer:1.81e-4 (unfavourable), Renal cancer:4.44e-4 (favourable) Mixed Tissue enhanced testis: 33.7 thyroid gland: 11.3 Mixed +SCP2D1 C20orf79, dJ1068E13.2, HSD22 ENSG00000132631 SCP2 sterol binding domain containing 1 20 18813726-18814392 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 593 testis: 59.2 all non-specific tissues: 0.0 Not detected +PCED1A bA12M19.1, C20orf81, FAM113A, FLJ22376 ENSG00000132635 PC-esterase domain containing 1A 20 2835314-2841190 Predicted intracellular proteins Evidence at protein level HPA050816 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:5.96e-5 (favourable), Liver cancer:7.31e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 81.5 Expressed in all +SNAP25 bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25 ENSG00000132639 Synaptosome associated protein 25 20 10218830-10307418 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level CAB000360, HPA001830 Enhanced Supported Group enriched Tissue enriched 31 cerebral cortex: 1759.0 adrenal gland: 57.2 Cell line enhanced SCLC-21H: 92.0;SH-SY5Y: 49.5;U-87 MG: 54.7 +BTBD3 dJ742J24.1, KIAA0952 ENSG00000132640 BTB domain containing 3 20 11890723-11926609 Predicted intracellular proteins Evidence at protein level HPA041424, HPA042048 Uncertain Supported Vesicles Liver cancer:2.51e-5 (unfavourable), Lung cancer:6.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 60.1 Cell line enhanced AN3-CA: 223.4;HeLa: 128.7 +PCNA ENSG00000132646 Proliferating cell nuclear antigen 20 5114953-5126626 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000148, HPA030521, HPA030522, HPA030523 Enhanced Supported Nucleoplasm
Nuclear bodies Renal cancer:3.03e-6 (unfavourable), Cervical cancer:1.86e-5 (favourable), Liver cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 223.2 Expressed in all +NXT1 MTR2, P15 ENSG00000132661 Nuclear transport factor 2 like export factor 1 20 23350736-23354777 Predicted intracellular proteins Evidence at protein level HPA047471 Supported Nucleoplasm
Cytosol Renal cancer:1.15e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 26.6 Expressed in all +POLR3F RPC39, RPC6 ENSG00000132664 RNA polymerase III subunit F 20 18467127-18484643 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA049441, HPA050173, HPA072298 Uncertain Approved Nucleus Liver cancer:8.87e-9 (unfavourable), Pancreatic cancer:6.48e-4 (favourable) Expressed in all Mixed thyroid gland: 11.6 Expressed in all +RIN2 RASSF4 ENSG00000132669 Ras and Rab interactor 2 20 19886521-20002457 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034641 Approved Approved Nucleoli
Golgi apparatus
Cytosol Renal cancer:8.34e-6 (favourable) Expressed in all Expressed in all gallbladder: 28.9 Cell line enhanced PC-3: 44.5 +PTPRA HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA ENSG00000132670 Protein tyrosine phosphatase, receptor type A 20 2864184-3039076 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA029412, CAB034366, HPA069480 Approved Approved Nucleus
Vesicles Renal cancer:3.29e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 167.4 Expressed in all +SSTR4 ENSG00000132671 Somatostatin receptor 4 20 23035386-23036812 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA064252 Uncertain Not detected Not detected cerebral cortex: 0.8 Not detected +DAP3 bMRP-10, DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29 ENSG00000132676 Death associated protein 3 1 155687960-155739010 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA023687 Approved Supported Nucleoplasm
Mitochondria Renal cancer:4.14e-6 (unfavourable), Liver cancer:1.20e-4 (unfavourable) Expressed in all Expressed in all breast: 82.0 Expressed in all +RHBG SLC42A2 ENSG00000132677 Rh family B glycoprotein (gene/pseudogene) 1 156369212-156385219 Predicted membrane proteins, Transporters Evidence at protein level HPA042726, HPA048489 Enhanced Approved Nucleoplasm Urothelial cancer:8.06e-4 (favourable) Group enriched Tissue enhanced kidney: 3.5;ovary: 2.1 esophagus,liver: 0.6 Group enriched 28 CACO-2: 2.1;Hep G2: 2.0;RT4: 4.3 +KIAA0907 BLOM7, SNORA80EHG ENSG00000132680 KIAA0907 1 155913043-155934400 Predicted intracellular proteins Evidence at protein level HPA008796 Approved Approved Nucleoplasm Renal cancer:2.78e-10 (unfavourable), Liver cancer:1.01e-6 (unfavourable), Urothelial cancer:4.36e-5 (favourable), Prostate cancer:3.87e-4 (unfavourable) Expressed in all Expressed in all epididymis: 55.3 Expressed in all +ATP1A4 ATP1AL2 ENSG00000132681 ATPase Na+/K+ transporting subunit alpha 4 1 160151570-160186977 Enzymes, Predicted membrane proteins Evidence at protein level Urothelial cancer:2.20e-4 (favourable) Group enriched Tissue enhanced placenta: 10.2;testis: 18.2;urinary bladder: 8.6 lymph node: 4.1 Group enriched 11 BEWO: 19.2;HDLM-2: 48.0;RT4: 49.0 +NES FLJ21841 ENSG00000132688 Nestin 1 156668763-156677397 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005889, HPA006286, HPA007007, HPA026111, CAB058692 Enhanced Enhanced Intermediate filaments Renal cancer:8.02e-7 (unfavourable) Group enriched Mixed heart muscle: 103.1 Cell line enhanced AF22: 620.1;HUVEC TERT2: 268.3;LHCN-M2: 427.4;RH-30: 502.3 +BCAN BEHAB, CSPG7, MGC13038 ENSG00000132692 Brevican 1 156641390-156659532 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA007865, CAB025862 Enhanced Supported Group enriched Tissue enriched 24 cerebral cortex: 428.3 epididymis: 18.0 Cell line enhanced HDLM-2: 67.3;K-562: 92.6;U-266/84: 84.7 +CRP PTX1 ENSG00000132693 C-reactive protein 1 159712289-159714589 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB005036, HPA027367, HPA027396 Supported Renal cancer:4.17e-10 (unfavourable) Tissue enriched Group enriched 67 gallbladder: 172.9;liver: 532.1 endometrium: 5.2 Cell line enhanced EFO-21: 5.9;HDLM-2: 5.8;U-2 OS: 4.4;U-266/84: 7.5 +ARHGEF11 GTRAP48, KIAA0380, PDZ-RHOGEF ENSG00000132694 Rho guanine nucleotide exchange factor 11 1 156934840-157045370 Predicted intracellular proteins Evidence at protein level HPA011026, HPA012037, HPA014658 Enhanced Approved Golgi apparatus
Plasma membrane Pancreatic cancer:1.72e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 44.3 Mixed +RAB25 CATX-8 ENSG00000132698 RAB25, member RAS oncogene family 1 156061160-156070514 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA010872, CAB033645 Enhanced Uncertain Cell Junctions
Cytosol Renal cancer:1.38e-6 (favourable) Mixed Tissue enhanced esophagus: 297.5 skin: 169.0 Cell line enhanced BEWO: 114.9;CAPAN-2: 103.6;MCF7: 128.3;RT4: 119.8;SK-BR-3: 179.2;T-47d: 210.8 +HAPLN2 BRAL1 ENSG00000132702 Hyaluronan and proteoglycan link protein 2 1 156619294-156625725 Predicted secreted proteins Evidence at protein level HPA045765 Enhanced Tissue enriched Tissue enriched 47 cerebral cortex: 42.1 duodenum: 0.8 Not detected +APCS MGC88159, PTX2, SAP ENSG00000132703 Amyloid P component, serum 1 159587825-159588865 Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level CAB007817, HPA053294 Supported Tissue enriched Tissue enriched 25 liver: 1851.8 gallbladder: 73.5 Cell line enhanced RH-30: 1.1 +FCRL2 CD307b, FCRH2, IRTA4, SPAP1 ENSG00000132704 Fc receptor like 2 1 157745733-157777132 CD markers, Predicted membrane proteins Evidence at protein level Mixed Group enriched 8 appendix: 16.3;lymph node: 28.4;spleen: 25.9;tonsil: 23.7 rectum: 3.0 Group enriched 27 Daudi: 9.2;U-266/70: 2.0;U-698: 7.2 +DCAF8 FLJ35857, H326, WDR42A ENSG00000132716 DDB1 and CUL4 associated factor 8 1 160215715-160262531 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027218, HPA027381 Approved Approved Nucleoplasm
Cytosol Renal cancer:3.74e-5 (unfavourable), Pancreatic cancer:4.71e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 155.7 Expressed in all +SYT11 DKFZp781D015, KIAA0080, MGC10881, MGC17226 ENSG00000132718 Synaptotagmin 11 1 155859509-155885199 Predicted intracellular proteins Evidence at protein level HPA064091 Enhanced Endometrial cancer:2.93e-5 (unfavourable) Tissue enriched Tissue enriched 14 cerebral cortex: 402.2 endometrium: 28.4 Cell line enhanced Karpas-707: 130.6;SCLC-21H: 84.6;SH-SY5Y: 83.1;U-87 MG: 84.4 +IGHMBP2 CATF1, CMT2S, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7 ENSG00000132740 Immunoglobulin mu binding protein 2 11 68903842-68940602 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA060994 Approved Nucleus Renal cancer:1.29e-8 (unfavourable), Pancreatic cancer:5.89e-4 (favourable) Expressed in all Expressed in all testis: 27.9 Expressed in all +ACY3 ACY-3, HCBP1, MGC9740 ENSG00000132744 Aminoacylase 3 11 67642555-67650659 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039219, HPA048187 Enhanced Endometrial cancer:4.80e-4 (favourable) Mixed Tissue enhanced duodenum: 80.6;kidney: 53.3;small intestine: 78.6 cervix, uterine: 16.1 Cell line enhanced CACO-2: 8.4;CAPAN-2: 13.6;Daudi: 41.2 +ALDH3B2 ALDH8 ENSG00000132746 Aldehyde dehydrogenase 3 family member B2 11 67662162-67681200 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045132 Enhanced Mixed Group enriched 6 breast: 89.9;esophagus: 103.4;skin: 122.2 tonsil: 19.0 Cell line enhanced MCF7: 49.6;SK-BR-3: 48.3;T-47d: 12.2 +TESMIN CXCDC2, MTL5 ENSG00000132749 Testis expressed metallothionein like protein 11 68707440-68751564 Predicted intracellular proteins Evidence at protein level HPA018539 Supported Nucleoplasm Endometrial cancer:1.75e-5 (unfavourable) Mixed Tissue enriched 17 testis: 95.3 breast: 5.5 Cell line enhanced T-47d: 22.3 +MMACHC cblC, DKFZP564I122 ENSG00000132763 Methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 1 45500053-45513382 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027394, HPA027399, HPA027402 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Mixed liver: 8.9 Expressed in all +DPH2 DPH2L2 ENSG00000132768 DPH2 homolog 1 43970000-43973369 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045796 Uncertain Approved Nucleus Liver cancer:1.17e-8 (unfavourable), Stomach cancer:1.37e-4 (favourable) Expressed in all Expressed in all lymph node: 14.3 Expressed in all +TOE1 hCaf1z ENSG00000132773 Target of EGR1, member 1 (nuclear) 1 45339670-45343975 Predicted intracellular proteins Evidence at protein level HPA053775, HPA069119 Enhanced Enhanced Nucleoplasm
Nuclear bodies Liver cancer:6.12e-9 (unfavourable), Renal cancer:2.71e-4 (unfavourable), Head and neck cancer:9.05e-4 (favourable), Stomach cancer:9.98e-4 (favourable) Expressed in all Mixed testis: 11.8 Expressed in all +NASP DKFZp547F162, FLB7527, FLJ31599, FLJ35510, MGC19722, MGC20372, MGC2297, PRO1999 ENSG00000132780 Nuclear autoantigenic sperm protein 1 45583846-45618904 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028136, HPA030518, HPA030520 Enhanced Enhanced Nucleoplasm Renal cancer:1.91e-8 (unfavourable), Liver cancer:4.96e-6 (unfavourable), Melanoma:3.67e-4 (unfavourable) Expressed in all Expressed in all testis: 149.6 Expressed in all +MUTYH MYH ENSG00000132781 MutY DNA glycosylase 1 45329163-45340470 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008732 Uncertain Supported Nucleus Liver cancer:4.76e-8 (unfavourable), Renal cancer:7.25e-5 (unfavourable) Expressed in all Mixed thyroid gland: 10.7 Expressed in all +CTNNBL1 C20orf33, FLJ21108, NAP, NYD-SP19, P14, P14L ENSG00000132792 Catenin beta like 1 20 37693955-37872129 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA004742, HPA027907 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 75.3 Expressed in all +LPIN3 LIPN3L, SMP2 ENSG00000132793 Lipin 3 20 41340920-41360582 Enzymes, Predicted intracellular proteins Evidence at protein level HPA051466, HPA052667, HPA070640 Approved Supported Cytosol Renal cancer:1.14e-5 (unfavourable), Ovarian cancer:1.74e-4 (unfavourable), Endometrial cancer:9.74e-4 (unfavourable) Expressed in all Mixed skin: 48.5 Mixed +ZSWIM3 C20orf164, dJ337O18.7, PPP1R174 ENSG00000132801 Zinc finger SWIM-type containing 3 20 45857617-45879122 Predicted intracellular proteins Evidence at protein level HPA055692, HPA060508 Uncertain Approved Nucleoli fibrillar center
Vesicles
Cytosol Breast cancer:9.32e-5 (unfavourable), Endometrial cancer:4.21e-4 (unfavourable) Expressed in all Mixed testis: 5.2 Mixed +RBM38 dJ800J21.2, HSRNASEB, RNPC1, seb4B, SEB4D ENSG00000132819 RNA binding motif protein 38 20 57391407-57409333 Predicted intracellular proteins Evidence at protein level CAB017036 Approved Supported Nucleoplasm
Cytosol Cervical cancer:3.64e-7 (favourable), Renal cancer:1.05e-5 (unfavourable), Thyroid cancer:1.63e-4 (favourable) Expressed in all Expressed in all bone marrow: 86.8 Mixed +VSTM2L C20orf102, dJ1118M15.2 ENSG00000132821 V-set and transmembrane domain containing 2 like 20 37903104-37945350 Predicted secreted proteins Evidence at protein level HPA043832 Uncertain Endometrial cancer:1.63e-5 (unfavourable), Urothelial cancer:8.14e-4 (unfavourable) Group enriched Tissue enhanced cerebral cortex: 55.1 gallbladder: 26.8 Cell line enhanced CAPAN-2: 58.1;HDLM-2: 86.5;SK-BR-3: 59.9 +OSER1 C20orf111, dJ1183I21.1, HSPC207, Osr1, Perit1 ENSG00000132823 Oxidative stress responsive serine rich 1 20 44196496-44210791 Predicted intracellular proteins Evidence at protein level HPA045125 Approved Approved Nucleoli
Nuclear speckles Endometrial cancer:2.58e-5 (unfavourable) Expressed in all Expressed in all testis: 184.6 Expressed in all +SERINC3 AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1 ENSG00000132824 Serine incorporator 3 20 44496221-44522109 Predicted membrane proteins, Transporters Evidence at protein level HPA048116 Uncertain Cervical cancer:1.01e-4 (unfavourable) Expressed in all Expressed in all testis: 201.7 Expressed in all +PPP1R3D PPP1R6 ENSG00000132825 Protein phosphatase 1 regulatory subunit 3D 20 59936668-59940297 Predicted intracellular proteins Evidence at protein level HPA041146 Approved Approved Nucleoli
Vesicles
Mitochondria Stomach cancer:9.14e-4 (favourable) Expressed in all Mixed parathyroid gland: 11.1 Mixed +DMGDH ENSG00000132837 Dimethylglycine dehydrogenase 5 78997606-79236038 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036441, HPA036442, HPA077849 Enhanced Supported Mitochondria Renal cancer:1.17e-5 (favourable), Liver cancer:5.32e-5 (favourable) Group enriched Group enriched 11 kidney: 179.1;liver: 146.2 epididymis: 14.9 Cell line enhanced BJ hTERT+: 2.9;Hep G2: 5.2 +BHMT2 ENSG00000132840 Betaine--homocysteine S-methyltransferase 2 5 79069717-79089466 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA044573 Enhanced Group enriched Group enriched 6 kidney: 362.7;liver: 238.5 epididymis: 46.2 Cell line enhanced Hep G2: 53.5;hTEC/SVTERT24-B: 46.4;U-87 MG: 18.9 +AP3B1 ADTB3A, HPS2 ENSG00000132842 Adaptor related protein complex 3 beta 1 subunit 5 78000525-78294755 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038737, HPA045458 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:7.97e-6 (favourable), Colorectal cancer:1.37e-5 (favourable) Expressed in all Expressed in all epididymis: 65.5 Expressed in all +ZBED3 MGC15435 ENSG00000132846 Zinc finger BED-type containing 3 5 77072072-77087323 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055995 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:1.68e-4 (favourable) Expressed in all Mixed thyroid gland: 18.8 Mixed +PATJ Cipp, INADL ENSG00000132849 PATJ, crumbs cell polarity complex component 1 61742477-62178675 Predicted intracellular proteins Evidence at protein level HPA066352, HPA066960, HPA069079 Approved Supported Cell Junctions
Microtubule organizing center
Cytosol Renal cancer:1.47e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 35.6 Cell line enhanced A-431: 31.4 +KANK4 ANKRD38, KIAA0172 ENSG00000132854 KN motif and ankyrin repeat domains 4 1 62236979-62319414 Predicted intracellular proteins Evidence at protein level HPA014030 Uncertain Uncertain Microtubules
Cytosol Mixed Tissue enhanced parathyroid gland: 29.5;placenta: 16.4 adipose tissue: 11.8 Cell line enhanced BEWO: 32.2;Hep G2: 9.9;SCLC-21H: 7.5 +ANGPTL3 ANGPT5 ENSG00000132855 Angiopoietin like 3 1 62597487-62606159 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA038097 Approved Tissue enriched Tissue enriched 6 liver: 356.4 kidney: 55.7 Not detected +SYT4 HsT1192, KIAA1342 ENSG00000132872 Synaptotagmin 4 18 43267878-43277650 Predicted intracellular proteins Evidence at protein level HPA010574 Approved Supported Vesicles
Plasma membrane Tissue enhanced Tissue enhanced adrenal gland: 20.4;cerebral cortex: 82.5 seminal vesicle: 11.3 Cell line enriched 10 SH-SY5Y: 251.0 +SLC14A2 HUT2, UT2 ENSG00000132874 Solute carrier family 14 member 2 18 45212995-45683686 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Tissue enhanced Tissue enhanced kidney: 4.0 adipose tissue: 1.6 Cell line enriched 5 U-266/70: 3.4 +FBXO44 FBG3, FBX30, Fbx44, Fbxo6a, MGC14140 ENSG00000132879 F-box protein 44 1 11654375-11663327 Predicted intracellular proteins Evidence at protein level HPA003363 Approved Approved Nucleoplasm Renal cancer:6.29e-5 (favourable), Pancreatic cancer:2.63e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 98.1 Mixed +RSG1 C1orf89, MGC10731 ENSG00000132881 REM2 and RAB like small GTPase 1 1 16231700-16237162 Predicted intracellular proteins Evidence at protein level HPA028453, HPA041672 Approved Enhanced Nucleoplasm Renal cancer:1.36e-10 (favourable) Expressed in all Mixed fallopian tube: 11.0 Mixed +CASP9 APAF-3, ICE-LAP6, MCH6, PPP1R56 ENSG00000132906 Caspase 9 1 15490832-15526534 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA001473, CAB004348, HPA046488 Approved Approved Mitochondria Urothelial cancer:1.67e-5 (favourable), Breast cancer:5.91e-4 (favourable) Expressed in all Expressed in all adrenal gland: 37.1 Expressed in all +NMUR2 NMU2R ENSG00000132911 Neuromedin U receptor 2 5 152391532-152433368 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA045836 Enhanced Group enriched Tissue enhanced stomach: 1.1;testis: 2.2 thyroid gland: 0.9 Cell line enriched 10 EFO-21: 8.9 +DCTN4 ENSG00000132912 Dynactin subunit 4 5 150708440-150759109 Predicted intracellular proteins Evidence at protein level CAB017532, HPA038026 Uncertain Approved Nucleus
Centrosome Expressed in all Expressed in all cerebral cortex: 67.3 Expressed in all +PDE6A PDEA, RP43 ENSG00000132915 Phosphodiesterase 6A 5 149857955-149944793 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA016970, HPA074677 Enhanced Not detected Tissue enriched 8 epididymis: 20.2 testis: 2.4 Cell line enhanced CACO-2: 2.1 +ATP8A2 ATPIB, ML-1 ENSG00000132932 ATPase phospholipid transporting 8A2 13 25372071-26025851 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA039926, HPA040033 Approved Supported Nucleoplasm
Plasma membrane Mixed Group enriched 6 cerebral cortex: 26.4;testis: 10.7 adrenal gland: 2.9 Cell line enhanced HMC-1: 19.3;SCLC-21H: 3.9 +MTUS2 CAZIP, ICIS, KIAA0774, TIP150 ENSG00000132938 Microtubule associated tumor suppressor candidate 2 13 28820348-29505947 Predicted intracellular proteins Evidence at protein level HPA031473, HPA031474, HPA031475 Enhanced Supported Microtubules
Cytokinetic bridge Mixed Group enriched 5 heart muscle: 33.4;ovary: 9.5 cerebral cortex: 4.2 Cell line enhanced HaCaT: 11.7;HeLa: 3.7 +ZMYM5 MYM, ZNF198L1, ZNF237 ENSG00000132950 Zinc finger MYM-type containing 5 13 19823482-19863636 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020879 Uncertain Expressed in all Expressed in all testis: 44.5 Expressed in all +USPL1 bA121O19.1, C13orf22, D13S106E ENSG00000132952 Ubiquitin specific peptidase like 1 13 30617693-30660770 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039342, HPA040172 Uncertain Expressed in all Expressed in all testis: 40.5 Expressed in all +XPO4 FLJ13046, KIAA1721 ENSG00000132953 Exportin 4 13 20777329-20903048 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA053768 Supported Nucleoplasm
Cytosol Liver cancer:4.63e-4 (unfavourable), Endometrial cancer:8.25e-4 (unfavourable) Expressed in all Mixed skeletal muscle: 15.7 Expressed in all +TPTE2 TPIP ENSG00000132958 Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 13 19422877-19536762 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA068342 Approved Endoplasmic reticulum
Cytosol Tissue enriched Tissue enriched 35 testis: 11.9 tonsil: 0.3 Cell line enhanced HDLM-2: 4.4 +POMP C13orf12, HSPC014, UMP1 ENSG00000132963 Proteasome maturation protein 13 28659104-28678925 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026995 Approved Supported Nuclear speckles Head and neck cancer:2.05e-5 (unfavourable) Expressed in all Expressed in all placenta: 146.5 Expressed in all +CDK8 K35 ENSG00000132964 Cyclin dependent kinase 8 13 26254104-26405238 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044721 Approved Nucleus Stomach cancer:9.23e-4 (favourable) Expressed in all Expressed in all testis: 17.7 Mixed +ALOX5AP FLAP ENSG00000132965 Arachidonate 5-lipoxygenase activating protein 13 30713478-30764426 Disease related genes, Predicted membrane proteins Evidence at protein level HPA026592 Enhanced Renal cancer:5.68e-4 (unfavourable), Ovarian cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 301.7 Cell line enhanced HDLM-2: 579.8;HL-60: 265.4;HMC-1: 899.6;THP-1: 279.0;U-937: 238.0 +WASF3 KIAA0900, SCAR3, WAVE3 ENSG00000132970 WAS protein family member 3 13 26557703-26688948 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB037086 Approved Pancreatic cancer:2.21e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 86.4 thyroid gland: 28.1 Cell line enhanced ASC diff: 56.8 +RNF17 FLJ11045, Mmip-2, SPATA23, TDRD4 ENSG00000132972 Ring finger protein 17 13 24764152-24879921 Predicted intracellular proteins Evidence at protein level HPA039699, HPA040111 Approved Tissue enriched Tissue enriched 19 testis: 44.0 placenta: 2.3 Not detected +GPR12 GPCR21, PPP1R84 ENSG00000132975 G protein-coupled receptor 12 13 26755200-26760785 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA050972 Uncertain Group enriched Tissue enhanced cerebral cortex: 7.9 breast: 1.7 Cell line enriched 8 SCLC-21H: 16.7 +CHRM3 ENSG00000133019 Cholinergic receptor muscarinic 3 1 239386565-239915452 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA024106, HPA048036 Approved Supported Plasma membrane Mixed Tissue enhanced cerebral cortex: 15.7 esophagus: 8.4 Cell line enhanced RPMI-8226: 11.9;SH-SY5Y: 55.3;U-266/70: 16.6;U-266/84: 11.6 +MYH8 MyHC-peri, MyHC-pn ENSG00000133020 Myosin heavy chain 8 17 10390322-10421950 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001349, CAB016527 Enhanced Tissue enhanced Group enriched 5 esophagus: 16.9;skeletal muscle: 5.5 prostate: 2.2 Cell line enriched 10 HSkMC: 5.2 +MYH10 NMMHCB ENSG00000133026 Myosin heavy chain 10 17 8474205-8630761 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017180, HPA047541, HPA057198 Enhanced Enhanced Actin filaments
Mitochondria
Cytosol Renal cancer:1.38e-4 (favourable), Urothelial cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all lung: 81.0 Cell line enhanced AF22: 213.4 +PEMT PEMPT, PEMT2 ENSG00000133027 Phosphatidylethanolamine N-methyltransferase 17 17505563-17591708 Enzymes, Predicted membrane proteins Evidence at protein level HPA042375 Approved Approved Cytosol Endometrial cancer:6.77e-6 (favourable) Expressed in all Expressed in all epididymis: 208.8 Expressed in all +SCO1 SCOD1 ENSG00000133028 SCO1, cytochrome c oxidase assembly protein 17 10672474-10698375 Disease related genes, Predicted membrane proteins Evidence at protein level HPA021565, HPA021579 Enhanced Renal cancer:9.69e-7 (favourable), Thyroid cancer:7.44e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 22.5 Expressed in all +MPRIP M-RIP, p116Rip, RHOIP3 ENSG00000133030 Myosin phosphatase Rho interacting protein 17 17042545-17217679 Predicted intracellular proteins Evidence at protein level HPA022034, HPA022901 Enhanced Supported Actin filaments
Cytosol Expressed in all Expressed in all smooth muscle: 197.8 Expressed in all +CHI3L1 GP39, YKL40 ENSG00000133048 Chitinase 3 like 1 1 203178931-203186749 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enhanced appendix: 186.7;cerebral cortex: 267.1;urinary bladder: 179.4 bone marrow: 146.9 Group enriched 7 ASC diff: 215.1;ASC TERT1: 484.9;HSkMC: 450.3;THP-1: 704.0;U-138 MG: 292.3;U-87 MG: 289.1 +MYBPH ENSG00000133055 Myosin binding protein H 1 203167811-203175813 Predicted intracellular proteins Evidence at protein level HPA061383 Enhanced Approved Nucleus
Nucleoli
Mitochondria Group enriched Group enriched 5 prostate: 5.1;skeletal muscle: 7.9 esophagus: 1.2 Cell line enhanced CACO-2: 25.5;HSkMC: 41.6;THP-1: 10.2 +PIK3C2B C2-PI3K, PI3K-C2beta ENSG00000133056 Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta 1 204422628-204494724 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030515, HPA050360 Approved Approved Nucleoplasm
Cytosol Urothelial cancer:1.16e-4 (favourable), Liver cancer:5.42e-4 (unfavourable) Expressed in all Mixed lymph node: 28.2 Cell line enhanced BEWO: 67.8;RT4: 60.2 +DSTYK DustyPK, KIAA0472, RIP5, RIPK5 ENSG00000133059 Dual serine/threonine and tyrosine protein kinase 1 205142505-205211566 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA044140 Uncertain Uncertain Nuclear speckles
Intermediate filaments Urothelial cancer:8.73e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 28.8 Expressed in all +CHIT1 CHI3, CHIT ENSG00000133063 Chitinase 1 1 203212827-203273641 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA010575 Approved Cervical cancer:2.02e-4 (favourable) Tissue enhanced Group enriched 14 bone marrow: 31.3;breast: 10.9;cervix, uterine: 13.5;lung: 53.2;lymph node: 21.0 prostate,thyroid gland: 1.8 Not detected +SLC41A1 MgtE ENSG00000133065 Solute carrier family 41 member 1 1 205789093-205813748 Predicted membrane proteins, Transporters Evidence at protein level HPA014721, HPA015138 Uncertain Approved Mitochondria Cervical cancer:1.48e-4 (unfavourable) Expressed in all Tissue enhanced heart muscle: 66.8 testis: 37.3 Mixed +LGR6 FLJ14471 ENSG00000133067 Leucine rich repeat containing G protein-coupled receptor 6 1 202193901-202319781 G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008556 Approved Approved Nucleoplasm
Plasma membrane Glioma:2.00e-4 (unfavourable) Tissue enhanced Tissue enhanced fallopian tube: 14.3 gallbladder: 9.6 Cell line enhanced A549: 15.6;CAPAN-2: 13.4;HaCaT: 7.3 +TMCC2 FLJ38497, HUCEP11 ENSG00000133069 Transmembrane and coiled-coil domain family 2 1 205228176-205273343 Predicted membrane proteins Evidence at protein level HPA014254 Approved Mixed Tissue enhanced bone marrow: 52.4;cerebral cortex: 15.1 placenta: 7.8 Cell line enhanced SCLC-21H: 41.5 +DCLK1 DCAMKL1, DCDC3A, DCLK, KIAA0369 ENSG00000133083 Doublecortin like kinase 1 13 35768652-36131306 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB012405, HPA015040, HPA015655 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:4.42e-4 (unfavourable) Tissue enhanced Tissue enriched 5 cerebral cortex: 140.5 smooth muscle: 27.3 Cell line enhanced ASC diff: 19.8;ASC TERT1: 19.0;fHDF/TERT166: 18.2;HAP1: 18.4;HSkMC: 18.4;NTERA-2: 36.7 +CCNA1 CT146 ENSG00000133101 Cyclin A1 13 36431520-36442882 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA060646 Approved Nucleoplasm
Nuclear bodies Head and neck cancer:1.70e-4 (unfavourable) Tissue enhanced Tissue enhanced parathyroid gland: 59.6;testis: 144.6 fallopian tube: 27.9 Cell line enhanced HMC-1: 300.4;THP-1: 46.6;U-937: 68.5 +COG6 COD2, KIAA1134 ENSG00000133103 Component of oligomeric golgi complex 6 13 39655627-39791665 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040410, HPA040441 Uncertain Approved Nuclear speckles
Golgi apparatus Stomach cancer:2.81e-4 (favourable) Expressed in all Expressed in all testis: 31.6 Expressed in all +SPG20 KIAA0610, TAHCCP1 ENSG00000133104 Spastic paraplegia 20 (Troyer syndrome) 13 36301638-36370180 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039053, HPA039054 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all epididymis: 81.4 Mixed +RXFP2 GPR106, GREAT, INSL3R, LGR8, RXFPR2 ENSG00000133105 Relaxin/insulin like family peptide receptor 2 13 31739542-31803388 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Not detected Not detected endometrium: 0.8 Not detected +EPSTI1 BRESI1, MGC29634 ENSG00000133106 Epithelial stromal interaction 1 13 42886388-42992271 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017362 Approved Approved Cytosol Renal cancer:1.02e-5 (unfavourable), Pancreatic cancer:1.66e-4 (unfavourable) Expressed in all Mixed spleen: 42.8 Cell line enhanced BJ hTERT+ SV40 Large T+: 89.2;BJ hTERT+ SV40 Large T+ RasG12V: 97.1;HDLM-2: 68.7 +TRPC4 HTRP4, TRP4 ENSG00000133107 Transient receptor potential cation channel subfamily C member 4 13 37636636-37870425 Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Mixed Tissue enhanced endometrium: 18.6;seminal vesicle: 12.1;smooth muscle: 18.5 prostate: 10.8 Cell line enhanced AF22: 8.0;BJ: 16.3;BJ hTERT+ SV40 Large T+: 7.5;fHDF/TERT166: 14.3;U-2197: 8.0 +POSTN OSF-2, periostin, PN ENSG00000133110 Periostin 13 37562583-37598844 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA012306 Enhanced Approved Nucleoplasm
Golgi apparatus Renal cancer:1.83e-7 (unfavourable), Lung cancer:2.93e-4 (unfavourable), Stomach cancer:4.86e-4 (unfavourable) Expressed in all Mixed skin: 246.4 Group enriched 7 hTEC/SVTERT24-B: 490.4;U-138 MG: 610.6;U-2197: 396.9 +RFXAP ENSG00000133111 Regulatory factor X associated protein 13 36819224-36829104 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA032035 Approved Nuclear speckles Lung cancer:2.26e-5 (favourable), Pancreatic cancer:4.18e-4 (favourable), Stomach cancer:4.91e-4 (favourable) Expressed in all Mixed testis: 12.2 Expressed in all +TPT1 fortilin, TCTP ENSG00000133112 Tumor protein, translationally-controlled 1 13 45333471-45341370 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008364, HPA039437 Approved Supported Cytosol Renal cancer:2.54e-5 (unfavourable), Thyroid cancer:4.31e-5 (favourable), Breast cancer:5.90e-5 (favourable), Endometrial cancer:2.35e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 8103.8 Expressed in all +GPALPP1 AD029, bA245H20.2, KIAA1704, LSR7 ENSG00000133114 GPALPP motifs containing 1 13 44989529-45037669 Predicted intracellular proteins Evidence at protein level HPA038966, HPA058739 Uncertain Approved Nucleus
Nucleoli Expressed in all Expressed in all thyroid gland: 15.4 Expressed in all +STOML3 Epb7.2l, SRO ENSG00000133115 Stomatin like 3 13 38965925-38991066 Predicted membrane proteins, Transporters Evidence at protein level HPA012892, HPA071011 Enhanced Enhanced Plasma membrane Endometrial cancer:1.49e-4 (favourable) Tissue enhanced Tissue enriched 18 fallopian tube: 50.3 lung: 2.8 Cell line enriched 33 AF22: 15.4 +KL ENSG00000133116 Klotho 13 33016433-33066145 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:1.29e-9 (favourable), Pancreatic cancer:4.44e-4 (favourable) Group enriched Group enriched 5 kidney: 136.6;parathyroid gland: 346.4 placenta: 44.1 Cell line enhanced HMC-1: 2.1;SK-BR-3: 3.4 +RFC3 MGC5276, RFC38 ENSG00000133119 Replication factor C subunit 3 13 33818049-33966558 Predicted intracellular proteins Evidence at protein level HPA030149 Approved Supported Nucleoplasm
Vesicles Expressed in all Mixed lymph node: 26.8 Expressed in all +STARD13 ARHGAP37, DLC2, GT650, LINC00464 ENSG00000133121 StAR related lipid transfer domain containing 13 13 33103135-33350630 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039535, HPA058867 Enhanced Approved Nuclear membrane
Nucleoli
Cytosol Renal cancer:1.23e-4 (unfavourable) Expressed in all Mixed placenta: 35.3 Cell line enhanced LHCN-M2: 41.8;WM-115: 40.0 +IRS4 IRS-4, PY160 ENSG00000133124 Insulin receptor substrate 4 X 108732482-108736409 Predicted secreted proteins Evidence at protein level HPA017372 Uncertain Mixed Tissue enhanced endometrium: 1.6;ovary: 4.3;thyroid gland: 2.1 cervix, uterine: 1.0 Cell line enhanced HEK 293: 8.2;RT4: 2.1;WM-115: 1.9 +MORC4 FLJ11565, ZCW4, ZCWCC2 ENSG00000133131 MORC family CW-type zinc finger 4 X 106813871-107000244 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA000395, HPA015547, HPA050250 Enhanced Enhanced Nucleoplasm Breast cancer:3.56e-5 (unfavourable) Expressed in all Expressed in all placenta: 114.4 Expressed in all +BEX2 DJ79P11.1 ENSG00000133134 Brain expressed X-linked 2 X 103309346-103311046 Predicted intracellular proteins Evidence at protein level HPA045384 Uncertain Renal cancer:3.05e-13 (favourable), Endometrial cancer:8.54e-7 (unfavourable), Lung cancer:1.52e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 226.5 thyroid gland: 156.9 Cell line enhanced hTCEpi: 64.4;NTERA-2: 86.5;SCLC-21H: 148.6;SH-SY5Y: 61.1 +RNF128 FLJ23516, GRAIL ENSG00000133135 Ring finger protein 128, E3 ubiquitin protein ligase X 106693794-106796993 Enzymes, Predicted membrane proteins Evidence at protein level HPA019675 Uncertain Renal cancer:1.07e-7 (unfavourable) Mixed Mixed small intestine: 66.9 Cell line enhanced BEWO: 40.1;CAPAN-2: 30.6;RT4: 70.6;WM-115: 52.6 +TBC1D8B FLJ20298, GRAMD8B, RP11-321G1.1 ENSG00000133138 TBC1 domain family member 8B X 106802680-106876145 Predicted intracellular proteins Evidence at protein level HPA023883, HPA027527 Enhanced Supported Approved Cytosol Mixed Mixed adrenal gland: 25.7 Mixed +TCEAL4 FLJ21174, WEX7 ENSG00000133142 Transcription elongation factor A like 4 X 103576231-103587736 Predicted intracellular proteins Evidence at protein level Head and neck cancer:3.11e-5 (unfavourable), Lung cancer:2.75e-4 (favourable) Expressed in all Expressed in all ovary: 555.7 Mixed +BEX1 ENSG00000133169 Brain expressed X-linked 1 X 103062651-103064240 Predicted intracellular proteins Evidence at protein level HPA045384 Approved Renal cancer:8.16e-8 (favourable), Breast cancer:6.43e-4 (favourable), Thyroid cancer:6.88e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 505.2 parathyroid gland: 154.3 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 525.2;HBF TERT88: 582.7;HL-60: 1113.6;SCLC-21H: 490.1 +FAM104A FLJ14775 ENSG00000133193 Family with sequence similarity 104 member A 17 73207353-73236753 Predicted intracellular proteins Evidence at protein level HPA021459 Approved Nucleoplasm
Cytosol Renal cancer:1.26e-10 (unfavourable), Liver cancer:2.12e-7 (unfavourable) Expressed in all Tissue enriched 6 testis: 163.8 bone marrow: 27.0 Expressed in all +SLC39A11 C17orf26 ENSG00000133195 Solute carrier family 39 member 11 17 72645949-73092712 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA021455 Approved Nucleoplasm Expressed in all Expressed in all thyroid gland: 60.1 Expressed in all +EPHB2 DRT, EPHT3, ERK, Hek5, Tyro5 ENSG00000133216 EPH receptor B2 1 22710839-22921500 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB013647, HPA071200 Approved Supported Nucleus
Plasma membrane Endometrial cancer:1.05e-5 (unfavourable), Colorectal cancer:4.98e-4 (favourable) Tissue enhanced Mixed rectum: 27.3 Cell line enhanced HUVEC TERT2: 71.2;TIME: 69.5 +SRRM1 MGC39488, POP101, SRM160 ENSG00000133226 Serine and arginine repetitive matrix 1 1 24631716-24673267 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA049941, HPA058612 Supported Enhanced Nuclear speckles Liver cancer:1.08e-4 (unfavourable) Expressed in all Expressed in all epididymis: 96.3 Expressed in all +BTBD2 ENSG00000133243 BTB domain containing 2 19 1985438-2034881 Predicted intracellular proteins Evidence at protein level Liver cancer:8.71e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 74.9 Expressed in all +PRAM1 PML-RAR ENSG00000133246 PML-RARA regulated adaptor molecule 1 19 8490056-8503112 Predicted intracellular proteins Evidence at protein level HPA045236, HPA050161 Approved Approved Golgi apparatus Renal cancer:8.08e-4 (unfavourable) Mixed Tissue enhanced bone marrow: 65.1 appendix: 15.2 Cell line enhanced HL-60: 18.4;THP-1: 26.7;U-937: 99.1 +KMT5C MGC2705, SUV420H2 ENSG00000133247 Lysine methyltransferase 5C 19 55339853-55348120 Enzymes, Predicted intracellular proteins Evidence at protein level HPA052294 Uncertain Approved Nucleoplasm Renal cancer:1.05e-8 (unfavourable) Expressed in all Mixed skin: 4.8 Cell line enhanced SCLC-21H: 21.9 +ZNF414 MGC15716, Zfp414 ENSG00000133250 Zinc finger protein 414 19 8509678-8514164 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053769 Approved Approved Nucleus
Cytosol Head and neck cancer:1.67e-6 (favourable), Endometrial cancer:4.17e-4 (favourable), Pancreatic cancer:4.59e-4 (favourable), Urothelial cancer:8.71e-4 (favourable) Expressed in all Expressed in all spleen: 12.3 Mixed +PDE6B CSNB3, CSNBAD2, PDEB, rd1, RP40 ENSG00000133256 Phosphodiesterase 6B 4 625584-670782 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA054148, HPA059929 Supported Approved Cytosol Lung cancer:5.34e-4 (favourable) Mixed Mixed cerebral cortex: 22.3 Cell line enhanced MOLT-4: 25.1;REH: 15.3;SCLC-21H: 23.8;SH-SY5Y: 12.6;U-266/84: 16.5 +HSPBP1 FES1, HspBP1 ENSG00000133265 HSPA (Hsp70) binding protein 1 19 55262231-55280381 Predicted intracellular proteins Evidence at protein level CAB005865, HPA071444 Enhanced Approved Vesicles
Cytosol Expressed in all Expressed in all fallopian tube: 40.1 Expressed in all +CSNK1G2 CK1g2 ENSG00000133275 Casein kinase 1 gamma 2 19 1941149-1981338 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034868, HPA056572 Uncertain Approved Vesicles Expressed in all Expressed in all testis: 76.8 Expressed in all +SLF1 ANKRD32, BRCTD1, BRCTx, DKFZp564C0469, DKFZp761C121 ENSG00000133302 SMC5-SMC6 complex localization factor 1 5 94618347-94739436 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040793, HPA054213 Uncertain Approved Nucleus Expressed in all Tissue enhanced testis: 12.9 cerebral cortex: 4.4 Cell line enhanced HeLa: 34.7 +CNDP2 CN2, CPGL, FLJ10830, HsT2298, PEPA ENSG00000133313 CNDP dipeptidase 2 (metallopeptidase M20 family) 18 74495816-74523454 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB026196, HPA036898, HPA036899 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:3.50e-6 (favourable) Expressed in all Expressed in all kidney: 342.2 Expressed in all +MACROD1 LRP16 ENSG00000133315 MACRO domain containing 1 11 63998558-64166106 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041031, HPA071075 Uncertain Supported Nucleoplasm Renal cancer:4.68e-6 (favourable), Pancreatic cancer:2.90e-4 (unfavourable) Expressed in all Tissue enriched 6 skeletal muscle: 106.6 kidney: 17.4 Cell line enhanced RPMI-8226: 99.7 +WDR74 FLJ10439 ENSG00000133316 WD repeat domain 74 11 62832342-62841809 Predicted intracellular proteins Evidence at protein level HPA037795, HPA038419 Uncertain Supported Nucleus
Nucleoli Expressed in all Expressed in all bone marrow: 82.7 Expressed in all +LGALS12 GRIP1 ENSG00000133317 Galectin 12 11 63506084-63516774 Predicted intracellular proteins Evidence at protein level Renal cancer:4.60e-7 (unfavourable) Mixed Tissue enriched 7 adipose tissue: 89.9 bone marrow: 12.5 Group enriched 15 ASC diff: 21.2;HL-60: 45.6;NB-4: 70.9;U-937: 93.2 +RTN3 ASYIP, HAP, NSPL2, NSPLII, RTN3-A1 ENSG00000133318 Reticulon 3 11 63681446-63759891 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015649, HPA015650 Enhanced Supported Endoplasmic reticulum Liver cancer:1.30e-6 (unfavourable), Renal cancer:9.87e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1030.6 Expressed in all +RARRES3 HRASLS4, TIG3 ENSG00000133321 Retinoic acid receptor responder 3 11 63536809-63546462 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Pancreatic cancer:6.26e-6 (unfavourable), Breast cancer:1.35e-5 (favourable), Cervical cancer:4.00e-4 (favourable) Expressed in all Expressed in all fallopian tube: 166.5 Cell line enhanced CAPAN-2: 203.5;RPTEC TERT1: 87.4;SK-BR-3: 131.4 +HRASLS2 FLJ20556 ENSG00000133328 HRAS like suppressor 2 11 63552770-63563383 Predicted membrane proteins Evidence at protein level HPA058997 Approved Approved Mitochondria Pancreatic cancer:5.27e-5 (unfavourable), Cervical cancer:6.87e-4 (favourable) Mixed Tissue enhanced duodenum: 67.6;small intestine: 46.5 rectum: 14.4 Cell line enriched 7 U-266/70: 97.6 +MYH11 SMHC, SMMHC ENSG00000133392 Myosin heavy chain 11 16 15703172-15857033 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002302, HPA014539, HPA015310 Enhanced Approved Plasma membrane
Cytosol Liver cancer:1.10e-5 (favourable) Tissue enhanced Tissue enhanced seminal vesicle: 1381.0;smooth muscle: 1022.0 prostate: 899.8 Cell line enhanced BEWO: 1.7;NB-4: 1.2;U-698: 3.4 +FOPNL C16orf63, DKFZp686N1651, FLJ31153, FOR20, PHSECRG2 ENSG00000133393 FGFR1OP N-terminal like 16 15865720-15888625 Predicted intracellular proteins Evidence at protein level HPA040599 Supported Supported Centrosome Expressed in all Expressed in all thyroid gland: 53.9 Expressed in all +MED10 L6, MGC5309, NUT2, TRG20 ENSG00000133398 Mediator complex subunit 10 5 6371881-6378594 Predicted intracellular proteins Evidence at protein level HPA042795, HPA054188 Supported Nucleoplasm Liver cancer:1.62e-6 (unfavourable), Renal cancer:2.19e-5 (unfavourable), Glioma:4.81e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 44.7 Expressed in all +PDZD2 KIAA0300, PDZK3 ENSG00000133401 PDZ domain containing 2 5 31639410-32110931 Predicted intracellular proteins Evidence at protein level CAB020784, HPA036503, HPA036504, HPA064387 Uncertain Approved Plasma membrane
Cytosol Mixed Mixed ovary: 18.3 Cell line enhanced BEWO: 8.1;SiHa: 12.6;SK-BR-3: 8.1 +MORC2 AC004542.C22.1, KIAA0852, ZCW3, ZCWCC1 ENSG00000133422 MORC family CW-type zinc finger 2 22 30925130-30968298 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000436 Enhanced Supported Nucleus
Cytosol Renal cancer:6.54e-8 (unfavourable) Expressed in all Expressed in all testis: 55.5 Expressed in all +LARGE1 KIAA0609, LARGE ENSG00000133424 LARGE xylosyl- and glucuronyltransferase 1 22 33162226-33922841 Disease related genes, Predicted intracellular proteins Evidence at protein level Expressed in all Mixed cerebral cortex: 43.2 Mixed +GSTT2B GSTT2P ENSG00000133433 Glutathione S-transferase theta 2B (gene/pseudogene) 22 23957414-23961186 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000750 Uncertain Supported Nucleoplasm
Cytosol Breast cancer:5.06e-4 (favourable) Expressed in all Tissue enriched 7 breast: 411.1 adrenal gland: 60.8 Cell line enhanced AN3-CA: 53.0;HHSteC: 68.3;T-47d: 60.4 +MYO18B BK125H2.1 ENSG00000133454 Myosin XVIIIB 22 25742144-26031041 Predicted intracellular proteins Evidence at protein level HPA000953 Uncertain Supported Nucleoplasm
Centrosome Mixed Group enriched 8 heart muscle: 47.3;skeletal muscle: 52.5 testis: 5.8 Cell line enhanced HDLM-2: 9.7;REH: 13.6;RH-30: 29.4;U-2 OS: 13.9;U-266/70: 7.2 +SLC2A11 GLUT10, GLUT11 ENSG00000133460 Solute carrier family 2 member 11 22 23856703-23886309 Predicted membrane proteins, Transporters Evidence at transcript level HPA042960, HPA071184 Uncertain Uncertain Nucleus
Cell Junctions Renal cancer:5.77e-7 (favourable), Pancreatic cancer:3.83e-4 (favourable) Mixed Mixed parathyroid gland: 10.9 Mixed +C1QTNF6 CTRP6, ZACRP6 ENSG00000133466 C1q and tumor necrosis factor related protein 6 22 37180167-37199385 Predicted intracellular proteins Evidence at protein level HPA002042 Enhanced Approved Nucleus Renal cancer:0.00e+0 (unfavourable), Lung cancer:9.60e-6 (unfavourable) Expressed in all Tissue enhanced endometrium: 52.3;placenta: 41.4 gallbladder: 13.5 Cell line enhanced MCF7: 83.4;RT4: 39.7 +GGT2 GGT ENSG00000133475 Gamma-glutamyltransferase 2 22 21207973-21227637 Predicted membrane proteins Evidence at protein level HPA045635, HPA047534, HPA065444 Supported Approved Vesicles Tissue enhanced Tissue enhanced lung: 1.3;thyroid gland: 1.5 breast,salivary gland: 0.9 Cell line enhanced HDLM-2: 1.5;HeLa: 2.0;U-2197: 8.2 +FAM83F ENSG00000133477 Family with sequence similarity 83 member F 22 39994949-40043529 Predicted intracellular proteins Evidence at protein level HPA051207, HPA064657 Enhanced Approved Nucleus
Mitochondria Colorectal cancer:1.73e-4 (favourable), Pancreatic cancer:9.40e-4 (favourable) Mixed Tissue enhanced testis: 21.6 skin: 16.5 Cell line enhanced hTCEpi: 27.3;RT4: 14.8;SCLC-21H: 46.9 +SEC14L4 dJ130H16.5, TAP3 ENSG00000133488 SEC14 like lipid binding 4 22 30488913-30505711 Predicted intracellular proteins Evidence at protein level HPA069748 Approved Centrosome Tissue enhanced Group enriched 8 bone marrow: 5.0;liver: 10.3;lung: 6.9;parathyroid gland: 10.5;testis: 7.1 adrenal gland: 0.9 Cell line enhanced A549: 6.7;BEWO: 36.9;SiHa: 9.8 +GIMAP6 FLJ22690, IAN6 ENSG00000133561 GTPase, IMAP family member 6 7 150625375-150632648 Predicted intracellular proteins Evidence at protein level HPA026715, HPA050740 Uncertain Uncertain Nucleoplasm
Cytosol Liver cancer:1.56e-4 (favourable), Head and neck cancer:2.91e-4 (favourable), Endometrial cancer:3.12e-4 (favourable), Renal cancer:5.27e-4 (unfavourable) Expressed in all Mixed spleen: 88.1 Cell line enhanced HUVEC TERT2: 104.1;MOLT-4: 34.5;TIME: 29.3 +GIMAP4 FLJ11110, HIMAP4, IAN1, IMAP4 ENSG00000133574 GTPase, IMAP family member 4 7 150567277-150573955 Predicted intracellular proteins Evidence at protein level HPA019135, HPA019137, HPA027198 Enhanced Renal cancer:1.13e-4 (unfavourable), Endometrial cancer:7.63e-4 (favourable) Expressed in all Expressed in all spleen: 147.7 Cell line enriched 23 HUVEC TERT2: 253.7 +ADCK2 MGC20727 ENSG00000133597 AarF domain containing kinase 2 7 140673153-140696261 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036036 Approved Uncertain Centrosome
Cytosol Renal cancer:9.75e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 27.2 Mixed +MKRN1 RNF61 ENSG00000133606 Makorin ring finger protein 1 7 140453040-140479569 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000567 Approved Nucleus
Nuclear membrane
Cytosol Expressed in all Expressed in all testis: 224.7 Expressed in all +AGAP3 CENTG3 ENSG00000133612 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 7 151085831-151144436 Predicted intracellular proteins Evidence at protein level HPA012883 Approved Renal cancer:8.58e-5 (unfavourable), Liver cancer:6.21e-4 (unfavourable), Colorectal cancer:9.52e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 92.5 Mixed +KRBA1 KIAA1862 ENSG00000133619 KRAB-A domain containing 1 7 149714781-149734575 Predicted intracellular proteins Evidence at protein level HPA021237, HPA050448 Approved Approved Nucleus
Cytosol Pancreatic cancer:2.77e-4 (favourable) Mixed Mixed heart muscle: 12.1 Mixed +ACTR3B ARP11, ARP3beta ENSG00000133627 ARP3 actin related protein 3 homolog B 7 152759749-152855378 Predicted intracellular proteins Evidence at protein level HPA047016, HPA051683 Uncertain Renal cancer:1.66e-4 (favourable), Stomach cancer:4.53e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 50.9 Mixed +NTS ENSG00000133636 Neurotensin 12 85874295-85882992 Predicted secreted proteins Evidence at protein level HPA026664 Enhanced Cervical cancer:9.94e-5 (favourable), Endometrial cancer:5.10e-4 (unfavourable) Tissue enhanced Group enriched 9 small intestine: 189.6;stomach: 43.5 lymph node: 13.4 Cell line enhanced HEL: 45.5;NTERA-2: 10.8 +BTG1 APRO2 ENSG00000133639 BTG anti-proliferation factor 1 12 92140278-92145897 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005972 Approved Nucleoplasm
Cytosol Renal cancer:1.95e-7 (unfavourable), Breast cancer:4.36e-5 (favourable) Expressed in all Expressed in all bone marrow: 261.0 Expressed in all +LRRIQ1 FLJ12303, KIAA1801 ENSG00000133640 Leucine rich repeats and IQ motif containing 1 12 85036314-85263224 Predicted intracellular proteins Evidence at protein level HPA046162 Uncertain Mixed Group enriched 7 fallopian tube: 13.7;testis: 25.7 parathyroid gland: 2.9 Cell line enhanced RPTEC TERT1: 2.2;SH-SY5Y: 2.1 +C12orf29 DKFZp434N2030 ENSG00000133641 Chromosome 12 open reading frame 29 12 88033846-88050160 Predicted intracellular proteins Evidence at protein level HPA039663 Uncertain Approved Vesicles Renal cancer:3.44e-4 (unfavourable) Expressed in all Mixed esophagus: 17.1 Expressed in all +ATP13A3 AFURS1 ENSG00000133657 ATPase 13A3 3 194402672-194498364 Predicted membrane proteins Evidence at protein level HPA029471 Approved Approved Nucleoli
Plasma membrane
Cytosol Pancreatic cancer:1.60e-4 (unfavourable), Renal cancer:1.63e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 149.3 Expressed in all +SFTPD COLEC7, SFTP4, SP-D ENSG00000133661 Surfactant protein D 10 79937740-79982614 Predicted secreted proteins Evidence at protein level CAB004578, HPA044582, HPA056768 Enhanced Tissue enriched Tissue enriched 56 lung: 782.5 bone marrow: 13.8 Cell line enhanced BEWO: 1.3;hTCEpi: 2.3;MCF7: 1.1 +DYDC2 bA36D19.6, MGC16186 ENSG00000133665 DPY30 domain containing 2 10 80344745-80368073 Predicted intracellular proteins Evidence at protein level HPA038006, HPA038007 Enhanced Ovarian cancer:3.54e-4 (favourable) Tissue enhanced Tissue enriched 10 fallopian tube: 153.3 testis: 15.0 Cell line enhanced AF22: 2.1;NTERA-2: 3.4;SCLC-21H: 3.4;SH-SY5Y: 2.1;U-2197: 2.0 +TMEM254 bA369J21.6, C10orf57, FLJ13263 ENSG00000133678 Transmembrane protein 254 10 80078646-80092557 Predicted membrane proteins Evidence at protein level HPA029105, HPA072613 Approved Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all skin: 85.7 Mixed +TMTC1 ARG99, FLJ31400, FLJ41625, OLF ENSG00000133687 Transmembrane and tetratricopeptide repeat containing 1 12 29500840-29784759 Predicted membrane proteins Evidence at protein level HPA016720 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:1.90e-4 (unfavourable), Renal cancer:5.49e-4 (unfavourable) Mixed Tissue enhanced spleen: 60.8 adipose tissue: 41.7 Cell line enhanced HHSteC: 71.4;hTERT-HME1: 81.2;RH-30: 120.9 +KRAS KRAS1, KRAS2 ENSG00000133703 KRAS proto-oncogene, GTPase 12 25204789-25250936 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA049830 Approved Renal cancer:2.75e-5 (favourable), Pancreatic cancer:3.59e-4 (unfavourable) Expressed in all Expressed in all rectum: 32.6 Expressed in all +IPO8 IMP8, RANBP8 ENSG00000133704 Importin 8 12 30628988-30695986 Predicted intracellular proteins, Transporters Evidence at protein level HPA018439, HPA023765 Uncertain Supported Nucleus Renal cancer:8.62e-5 (favourable), Liver cancer:1.35e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 120.8 Expressed in all +LARS FLJ10595, FLJ21788, HSPC192, LARS1, LEUS, RNTLS ENSG00000133706 Leucyl-tRNA synthetase 5 146113038-146182660 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036424, HPA040881 Supported Supported Nuclear bodies
Cytosol Liver cancer:3.78e-5 (unfavourable), Thyroid cancer:2.98e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 70.8 Expressed in all +SPINK5 DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI ENSG00000133710 Serine peptidase inhibitor, Kazal type 5 5 148025683-148137289 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA009067, HPA011351, CAB015347 Enhanced Enhanced Vesicles Tissue enhanced Group enriched 26 esophagus: 1130.0;skin: 383.9;tonsil: 270.0 breast: 22.9 Cell line enhanced HaCaT: 13.2;HeLa: 14.7;Karpas-707: 13.8 +IMPA1 IMPA ENSG00000133731 Inositol monophosphatase 1 8 81657961-81686693 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037489 Approved Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all testis: 72.0 Expressed in all +LRRCC1 CLERC, KIAA1764, VFL1 ENSG00000133739 Leucine rich repeat and coiled-coil centrosomal protein 1 8 85107147-85146076 Predicted intracellular proteins Evidence at protein level HPA012893 Uncertain Expressed in all Tissue enhanced testis: 57.8 thyroid gland: 14.2 Cell line enhanced HDLM-2: 38.0 +E2F5 ENSG00000133740 E2F transcription factor 5 8 85177225-85217158 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA055723 Supported Nucleus
Nucleoli Renal cancer:1.89e-6 (unfavourable) Expressed in all Mixed lymph node: 30.9 Cell line enhanced AF22: 76.4;Daudi: 112.8 +CA1 Car1 ENSG00000133742 Carbonic anhydrase 1 8 85327608-85379014 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006558, CAB025790 Enhanced Group enriched Group enriched 30 bone marrow: 1216.6;colon: 1022.8;rectum: 2316.0 smooth muscle: 49.9 Cell line enriched 1560 HEL: 1145.7 +CCDC59 BR22, HSPC128, TAP26 ENSG00000133773 Coiled-coil domain containing 59 12 82223681-82358805 Predicted intracellular proteins Evidence at protein level HPA038555 Approved Approved Nucleus
Nucleoli Renal cancer:1.39e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 27.4 Expressed in all +SWAP70 KIAA0640, SWAP-70 ENSG00000133789 SWAP switching B-cell complex subunit 70 11 9664077-9752991 Predicted intracellular proteins Evidence at protein level HPA006810 Supported Expressed in all Expressed in all spleen: 82.2 Mixed +ARNTL bHLHe5, BMAL1, JAP3, MOP3, PASD3 ENSG00000133794 Aryl hydrocarbon receptor nuclear translocator like 11 13276652-13387266 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level CAB045962, HPA050938 Supported Supported Nucleoplasm
Vesicles Expressed in all Expressed in all adrenal gland: 26.3 Mixed +LYVE1 LYVE-1, XLKD1 ENSG00000133800 Lymphatic vessel endothelial hyaluronan receptor 1 11 10556966-10611689 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB025860, HPA042953 Supported Renal cancer:6.98e-5 (unfavourable), Ovarian cancer:1.07e-4 (unfavourable) Mixed Tissue enhanced adipose tissue: 157.5;placenta: 213.1 smooth muscle: 95.3 Cell line enriched 11 HUVEC TERT2: 67.8 +AMPD3 ENSG00000133805 Adenosine monophosphate deaminase 3 11 10308313-10507579 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038662, HPA047408 Uncertain Enhanced Nuclear membrane Endometrial cancer:2.37e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 54.4 bone marrow: 41.4 Cell line enhanced BJ hTERT+: 35.8 +MICALCL FLJ14966 ENSG00000133808 MICAL C-terminal like 11 12276080-12359144 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA039895, HPA040438 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Mixed Tissue enhanced skin: 17.3;testis: 13.4 lung: 10.3 Cell line enhanced HBEC3-KT: 18.3;RT4: 12.1;U-2 OS: 9.9 +SBF2 CMT4B2, DENND7B, KIAA1766, MTMR13 ENSG00000133812 SET binding factor 2 11 9778667-10294207 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050933 Uncertain Approved Nucleoplasm
Intermediate filaments
Cytosol Renal cancer:3.66e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 38.1 Expressed in all +MICAL2 KIAA0750 ENSG00000133816 Microtubule associated monooxygenase, calponin and LIM domain containing 2 11 12094008-12263789 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030437 Approved Approved Golgi apparatus Renal cancer:3.63e-5 (unfavourable) Expressed in all Mixed testis: 79.8 Cell line enhanced U-138 MG: 131.4 +RRAS2 TC21 ENSG00000133818 Related RAS viral (r-ras) oncogene homolog 2 11 14277926-14364506 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010420, HPA050942 Approved Approved Nucleus
Cytosol Pancreatic cancer:2.44e-4 (unfavourable), Liver cancer:3.31e-4 (unfavourable), Head and neck cancer:7.80e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 50.3 Mixed +HSD17B4 DBP, MFE-2, SDR8C1 ENSG00000133835 Hydroxysteroid 17-beta dehydrogenase 4 5 119452443-119637199 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021302, HPA021311, HPA021479 Enhanced Enhanced Peroxisomes Renal cancer:6.31e-6 (favourable), Colorectal cancer:1.33e-4 (favourable) Expressed in all Expressed in all thyroid gland: 229.7 Expressed in all +ZFC3H1 CCDC131, CSRC2, KIAA0546, MGC23401, PSRC2 ENSG00000133858 Zinc finger C3H1-type containing 12 71609472-71667725 Predicted intracellular proteins Evidence at protein level HPA007072, HPA007151 Enhanced Approved Nucleoplasm
Intermediate filaments Renal cancer:1.48e-5 (unfavourable), Liver cancer:3.63e-4 (unfavourable) Expressed in all Mixed testis: 19.1 Expressed in all +TEX15 CT42 ENSG00000133863 Testis expressed 15, meiosis and synapsis associated 8 30831544-30890606 Predicted intracellular proteins Evidence at protein level HPA036799, HPA036800 Enhanced Approved Nuclear speckles Not detected Group enriched 32 endometrium: 11.0;smooth muscle: 8.3;testis: 22.3 cerebral cortex,gallbladder: 0.4 Cell line enhanced HAP1: 8.7;HEL: 17.3;K-562: 4.9;SCLC-21H: 4.9 +SARAF MGC8721, TMEM66 ENSG00000133872 Store-operated calcium entry associated regulatory factor 8 30063012-30083208 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA040400 Supported Endoplasmic reticulum
Rods & Rings Lung cancer:5.28e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 287.0 Expressed in all +RNF122 FLJ12526 ENSG00000133874 Ring finger protein 122 8 33547755-33567125 Predicted membrane proteins Evidence at transcript level HPA003888 Uncertain Renal cancer:4.50e-7 (unfavourable), Thyroid cancer:1.88e-4 (unfavourable), Prostate cancer:5.37e-4 (favourable) Expressed in all Expressed in all fallopian tube: 21.6 Cell line enhanced HEK 293: 76.9;Karpas-707: 38.8 +DUSP26 DUSP24, MGC1136 ENSG00000133878 Dual specificity phosphatase 26 8 33591332-33600106 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018221 Approved Supported Nucleus Tissue enhanced Tissue enhanced cerebral cortex: 47.1;skeletal muscle: 138.7 ovary: 39.6 Group enriched 29 SCLC-21H: 110.0;SH-SY5Y: 23.6 +DPF2 BAF45d, REQ, ubi-d4 ENSG00000133884 Double PHD fingers 2 11 65333754-65353249 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020880, HPA056786 Approved Supported Nucleoplasm Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 52.1 Expressed in all +MEN1 ENSG00000133895 Menin 1 11 64803510-64811294 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030342 Uncertain Supported Nucleoplasm
Cytosol Stomach cancer:6.31e-5 (favourable), Liver cancer:1.08e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 22.3 Expressed in all +C14orf1 ERG28, NET51 ENSG00000133935 Chromosome 14 open reading frame 1 14 75649791-75661189 Predicted membrane proteins Evidence at protein level HPA043172, HPA063568 Approved Approved Nucleoplasm
Cytosol Renal cancer:4.30e-5 (favourable) Expressed in all Expressed in all testis: 77.2 Expressed in all +GSC ENSG00000133937 Goosecoid homeobox 14 94768216-94770230 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA075650 Approved Nucleus
Nuclear bodies Mixed Tissue enhanced adipose tissue: 2.1 breast: 1.1 Cell line enhanced HEK 293: 1.7;MCF7: 2.1;REH: 2.6;SH-SY5Y: 3.3;T-47d: 2.1;U-251 MG: 1.8 +C14orf159 FLJ39975 ENSG00000133943 Chromosome 14 open reading frame 159 14 91060333-91225632 Predicted intracellular proteins Evidence at protein level HPA041423, HPA052932 Approved Supported Cytosol Renal cancer:3.77e-15 (favourable), Lung cancer:9.48e-5 (favourable), Endometrial cancer:4.28e-4 (favourable), Ovarian cancer:7.28e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 82.6 Expressed in all +UNC79 KIAA1409 ENSG00000133958 Unc-79 homolog (C. elegans) 14 93333219-93707876 Predicted membrane proteins Evidence at protein level HPA071881 Approved Nucleus
Plasma membrane Mixed Tissue enhanced cerebral cortex: 5.2;testis: 3.0 adrenal gland: 1.0 Cell line enhanced REH: 3.9;SCLC-21H: 3.6;SH-SY5Y: 2.0;U-937: 1.2 +NUMB C14orf41 ENSG00000133961 NUMB, endocytic adaptor protein 14 73275107-73463642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA002874, CAB011478 Approved Enhanced Cell Junctions
Cytosol Renal cancer:2.32e-6 (favourable) Expressed in all Expressed in all lung: 78.0 Expressed in all +CATSPERB C14orf161, FLJ14298 ENSG00000133962 Cation channel sperm associated auxiliary subunit beta 14 91580696-91780707 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA035134 Uncertain Uncertain Vesicles Mixed Mixed skin: 2.7 Cell line enhanced CAPAN-2: 1.1 +VRTN C14orf115, FLJ10811, vertnin ENSG00000133980 Vertebrae development associated 14 74303069-74360008 Predicted intracellular proteins Evidence at protein level HPA001460 Uncertain Approved Nucleoplasm Tissue enriched Tissue enhanced epididymis: 1.8;testis: 2.9 lymph node: 0.5 Cell line enriched 10 NTERA-2: 49.5 +COX16 C14orf112, HSPC203 ENSG00000133983 COX16, cytochrome c oxidase assembly homolog 14 70325081-70359731 Predicted intracellular proteins Evidence at protein level HPA062659 Uncertain Supported Mitochondria Renal cancer:1.03e-12 (favourable) Expressed in all Expressed in all thyroid gland: 39.6 Expressed in all +TTC9 KIAA0227, TTC9A ENSG00000133985 Tetratricopeptide repeat domain 9 14 70641787-70675360 Predicted intracellular proteins Evidence at protein level Renal cancer:2.10e-8 (favourable), Endometrial cancer:1.82e-5 (favourable) Expressed in all Tissue enhanced esophagus: 44.6 fallopian tube: 15.9 Cell line enhanced A-431: 15.5;RH-30: 20.2;SK-BR-3: 26.6 +MED6 NY-REN-28 ENSG00000133997 Mediator complex subunit 6 14 70581257-70600690 Predicted intracellular proteins Evidence at protein level HPA030764, HPA069039 Approved Enhanced Nucleoplasm Liver cancer:1.04e-4 (unfavourable), Melanoma:2.75e-4 (unfavourable) Expressed in all Expressed in all lymph node: 28.6 Expressed in all +EIF2S1 EIF-2alpha, EIF2, EIF2A ENSG00000134001 Eukaryotic translation initiation factor 2 subunit alpha 14 67359997-67386516 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011663, HPA064885 Supported Enhanced Nucleoplasm
Cytosol Liver cancer:4.73e-7 (unfavourable), Pancreatic cancer:4.97e-4 (unfavourable), Urothelial cancer:7.11e-4 (unfavourable) Expressed in all Expressed in all testis: 61.1 Expressed in all +ADAM20 ENSG00000134007 ADAM metallopeptidase domain 20 14 70522358-70535015 Predicted membrane proteins Evidence at protein level HPA059377 Enhanced Not detected Tissue enriched 77 testis: 9.2 cerebral cortex,endometrium,epididymis,skin: 0.1 Not detected +LOXL2 WS9-14 ENSG00000134013 Lysyl oxidase like 2 8 23297189-23425328 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025848, HPA036257, HPA056542 Approved Approved Nucleoplasm Lung cancer:1.46e-7 (unfavourable), Renal cancer:2.91e-7 (unfavourable), Cervical cancer:9.83e-6 (unfavourable), Glioma:1.78e-4 (unfavourable), Pancreatic cancer:9.05e-4 (unfavourable) Expressed in all Tissue enhanced smooth muscle: 59.8 placenta: 53.3 Cell line enhanced BJ: 809.1;U-87 MG: 911.1 +ELP3 FLJ10422, KAT9 ENSG00000134014 Elongator acetyltransferase complex subunit 3 8 28089673-28191156 Enzymes, Predicted intracellular proteins Evidence at protein level HPA025812 Uncertain Renal cancer:1.31e-5 (favourable), Colorectal cancer:9.25e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 37.6 Expressed in all +PEBP4 CORK1, hPEBP4, MGC22776 ENSG00000134020 Phosphatidylethanolamine binding protein 4 8 22713251-23000000 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA025064 Uncertain Group enriched Tissue enhanced epididymis: 470.5;lung: 173.6;skeletal muscle: 233.0 thyroid gland: 96.3 Cell line enriched 7 U-266/70: 3.0 +ADAMDEC1 M12.219 ENSG00000134028 ADAM like decysin 1 8 24384285-24406013 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Expressed in all Tissue enhanced colon: 210.9;rectum: 339.7;small intestine: 476.3 duodenum: 189.1 Group enriched 7 U-266/70: 8.1;U-266/84: 1.9 +CTIF KIAA0427 ENSG00000134030 Cap binding complex dependent translation initiation factor 18 48539046-48863217 Predicted intracellular proteins, Transporters Evidence at protein level HPA016865, HPA024801 Uncertain Supported Cytosol Renal cancer:3.18e-4 (favourable) Expressed in all Mixed cerebral cortex: 24.9 Mixed +MRO B29, C18orf3, FLJ30140 ENSG00000134042 Maestro 18 50795120-50825402 Predicted intracellular proteins Evidence at transcript level HPA022011 Approved Tissue enriched Tissue enhanced cerebral cortex: 27.5;kidney: 25.5;testis: 54.7 thyroid gland: 10.4 Cell line enhanced ASC diff: 1.9;ASC TERT1: 6.0 +MBD2 ENSG00000134046 Methyl-CpG binding domain protein 2 18 54151601-54224788 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB037282, HPA067582, HPA067615 Approved Enhanced Nucleoplasm Colorectal cancer:6.49e-4 (favourable) Expressed in all Expressed in all thyroid gland: 50.6 Expressed in all +IER3IP1 ENSG00000134049 Immediate early response 3 interacting protein 1 18 47152834-47176374 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010027 Supported Supported Endoplasmic reticulum Liver cancer:6.47e-6 (unfavourable), Ovarian cancer:8.59e-4 (favourable) Expressed in all Expressed in all kidney: 32.8 Expressed in all +MRPS36 DC47, MRP-S36 ENSG00000134056 Mitochondrial ribosomal protein S36 5 69217760-69230129 Predicted intracellular proteins Evidence at protein level HPA035802, HPA056795 Supported Enhanced Mitochondria Renal cancer:5.02e-6 (favourable) Expressed in all Expressed in all kidney: 52.2 Expressed in all +CCNB1 CCNB ENSG00000134057 Cyclin B1 5 69167010-69178245 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB000115, CAB003804, HPA030741, HPA061448 Enhanced Enhanced Cytosol Renal cancer:1.11e-16 (unfavourable), Liver cancer:1.54e-7 (unfavourable), Lung cancer:3.38e-4 (unfavourable) Expressed in all Mixed lymph node: 65.5 Expressed in all +CDK7 CAK, CAK1, CDKN7, MO15, STK1 ENSG00000134058 Cyclin dependent kinase 7 5 69234795-69277430 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004364, HPA007932 Enhanced Renal cancer:9.42e-7 (unfavourable), Pancreatic cancer:3.09e-4 (unfavourable) Expressed in all Mixed testis: 23.7 Mixed +CD180 LY64, Ly78, RP105 ENSG00000134061 CD180 molecule 5 67179613-67196799 CD markers, Predicted membrane proteins Evidence at protein level HPA003740 Enhanced Mixed Tissue enhanced lymph node: 27.4;tonsil: 21.3 spleen: 17.8 Group enriched 11 Daudi: 32.2;Karpas-707: 29.5;U-266/70: 25.3;U-266/84: 34.5;U-698: 8.6 +IRAK2 ENSG00000134070 Interleukin 1 receptor associated kinase 2 3 10164865-10243743 Enzymes, Predicted intracellular proteins Evidence at protein level CAB013483, HPA050520 Uncertain Approved Vesicles Urothelial cancer:6.60e-5 (favourable), Pancreatic cancer:2.26e-4 (unfavourable), Liver cancer:8.35e-4 (unfavourable) Expressed in all Mixed bone marrow: 14.6 Cell line enhanced BEWO: 31.5;BJ hTERT+: 28.0;CAPAN-2: 30.8;RT4: 38.6 +CAMK1 CaMKI ENSG00000134072 Calcium/calmodulin dependent protein kinase I 3 9757342-9769992 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB031904, HPA051409 Approved Approved Cytosol Liver cancer:7.52e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 107.7 Cell line enhanced HMC-1: 344.4 +THUMPD3 DKFZP434F091 ENSG00000134077 THUMP domain containing 3 3 9362842-9386791 Predicted intracellular proteins Evidence at protein level HPA036170, HPA036171 Approved Approved Nucleoli
Cytosol Liver cancer:1.25e-7 (unfavourable), Renal cancer:1.03e-4 (favourable) Expressed in all Expressed in all testis: 107.5 Expressed in all +VHL VHL1 ENSG00000134086 Von Hippel-Lindau tumor suppressor 3 10141008-10152220 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB005430, HPA031631, HPA031632 Uncertain Enhanced Nucleoplasm
Cytosol Liver cancer:1.32e-5 (unfavourable), Breast cancer:9.02e-5 (unfavourable), Stomach cancer:7.84e-4 (favourable) Expressed in all Expressed in all lymph node: 34.7 Expressed in all +BHLHE40 BHLHB2, bHLHe40, Clast5, DEC1, SHARP2, STRA13 ENSG00000134107 Basic helix-loop-helix family member e40 3 4979116-4985323 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028922 Uncertain Supported Nuclear bodies Pancreatic cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all esophagus: 230.0 Cell line enhanced HDLM-2: 406.6;U-87 MG: 191.8 +ARL8B ARL10C, FLJ10702, Gie1 ENSG00000134108 ADP ribosylation factor like GTPase 8B 3 5122220-5180912 Predicted intracellular proteins Evidence at protein level HPA038759, HPA040515, HPA045924 Approved Liver cancer:3.68e-6 (unfavourable), Renal cancer:4.84e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 118.6 Expressed in all +EDEM1 EDEM, KIAA0212 ENSG00000134109 ER degradation enhancing alpha-mannosidase like protein 1 3 5187646-5219957 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029565 Uncertain Approved Endoplasmic reticulum Expressed in all Expressed in all lymph node: 47.7 Expressed in all +CNTN6 NB-3 ENSG00000134115 Contactin 6 3 1092576-1404217 Predicted membrane proteins Evidence at protein level HPA016645 Uncertain Group enriched Tissue enhanced lung: 4.6;thyroid gland: 17.4 cerebral cortex: 4.0 Group enriched 22 AF22: 2.0;SH-SY5Y: 2.4 +CHL1 CALL, FLJ44930, L1CAM2, MGC132578 ENSG00000134121 Cell adhesion molecule L1 like 3 196596-409417 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003345, CAB026120 Enhanced Renal cancer:1.21e-6 (favourable) Tissue enhanced Tissue enriched 5 cerebral cortex: 111.8 ovary: 20.9 Group enriched 6 SK-MEL-30: 73.7;WM-115: 29.2 +MEIS2 HsT18361, MRG1 ENSG00000134138 Meis homeobox 2 15 36889204-37101299 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003256, CAB004999 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:2.64e-7 (unfavourable) Mixed Mixed endometrium: 63.5 Cell line enhanced fHDF/TERT166: 89.3;SH-SY5Y: 111.8 +DPH6 ATPBD4, MGC14798 ENSG00000134146 Diphthamine biosynthesis 6 15 35217345-35546193 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042976, HPA055496 Approved Enhanced Nucleus
Nucleoli Expressed in all Expressed in all thyroid gland: 18.1 Expressed in all +KATNBL1 C15orf29, FLJ22557 ENSG00000134152 Katanin regulatory subunit B1 like 1 15 34140674-34210096 Predicted intracellular proteins Evidence at protein level HPA062573 Approved Approved Nucleus
Midbody
Mitotic spindle Renal cancer:4.60e-5 (unfavourable) Expressed in all Expressed in all placenta: 46.7 Expressed in all +EMC7 C11orf3, C15orf24 ENSG00000134153 ER membrane protein complex subunit 7 15 34084017-34101948 Predicted membrane proteins Evidence at protein level HPA010029, HPA047572 Approved Approved Nucleoplasm Endometrial cancer:4.68e-5 (favourable), Head and neck cancer:9.25e-5 (unfavourable) Expressed in all Expressed in all testis: 129.8 Expressed in all +TRPM1 CSNB1C, LTRPC1, MLSN1 ENSG00000134160 Transient receptor potential cation channel subfamily M member 1 15 31001061-31161273 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA014779, HPA014785 Supported Uncertain Nucleoplasm
Cytosol Tissue enriched Group enriched 26 skin: 4.8;testis: 2.1 kidney: 0.1 Cell line enriched 91 SK-MEL-30: 9.1 +GNAT2 ACHM4 ENSG00000134183 G protein subunit alpha transducin 2 1 109603267-109619929 Disease related genes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 6 testis: 3.9 placenta: 0.6 Cell line enhanced HAP1: 2.0 +GSTM1 GST1, H-B, MU ENSG00000134184 Glutathione S-transferase mu 1 1 109687814-109709039 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022669, CAB047357, HPA048652, HPA055972, HPA055973 Approved Approved Cytosol Expressed in all Tissue enhanced liver: 317.1 parathyroid gland: 233.1 Cell line enhanced HEL: 78.7;HeLa: 68.9;HHSteC: 66.1;hTEC/SVTERT24-B: 72.9;MOLT-4: 92.2 +PRPF38B FLJ10330, NET1 ENSG00000134186 Pre-mRNA processing factor 38B 1 108692323-108701803 Predicted intracellular proteins Evidence at protein level HPA053255 Approved Renal cancer:2.03e-4 (unfavourable), Liver cancer:2.26e-4 (unfavourable) Expressed in all Expressed in all lymph node: 51.7 Expressed in all +REG4 GISP, REG-IV, RELP ENSG00000134193 Regenerating family member 4 1 119794018-119811660 Predicted secreted proteins Evidence at protein level CAB025867, HPA046555 Enhanced Group enriched Group enriched 9 colon: 215.7;duodenum: 239.5;rectum: 299.4;small intestine: 664.5 appendix: 39.6 Group enriched 24 PC-3: 85.3;RT4: 20.5 +TSPAN2 FLJ12082, TSN2, TSPAN-2 ENSG00000134198 Tetraspanin 2 1 115048011-115089500 Predicted membrane proteins Evidence at protein level HPA015640 Uncertain Approved Nucleoplasm Renal cancer:8.48e-7 (unfavourable), Endometrial cancer:8.89e-4 (unfavourable) Mixed Tissue enhanced endometrium: 71.7;smooth muscle: 64.6 seminal vesicle: 40.5 Cell line enhanced EFO-21: 58.1;U-937: 21.9 +TSHB ENSG00000134200 Thyroid stimulating hormone beta 1 115029824-115034309 Predicted secreted proteins Evidence at protein level CAB022202, HPA042681 Supported Not detected Not detected gallbladder: 0.5 Not detected +GSTM5 ENSG00000134201 Glutathione S-transferase mu 5 1 109712255-109775428 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048652, HPA055972, HPA055973 Approved Approved Cytokinetic bridge
Cytosol Mixed Group enriched 6 breast: 845.2;ovary: 221.0 fallopian tube: 84.6 Group enriched 8 fHDF/TERT166: 12.9;HHSteC: 5.7;HSkMC: 5.3 +GSTM3 GST5 ENSG00000134202 Glutathione S-transferase mu 3 1 109733932-109741038 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB017130, HPA035190, CAB040583, HPA055972 Enhanced Supported Cytosol Melanoma:1.89e-4 (unfavourable) Expressed in all Expressed in all testis: 722.1 Cell line enhanced T-47d: 462.4 +SYT6 ENSG00000134207 Synaptotagmin 6 1 114089291-114153919 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058362 Uncertain Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 6.5 kidney: 1.5 Group enriched 7 NTERA-2: 23.0;WM-115: 16.3 +VAV3 ENSG00000134215 Vav guanine nucleotide exchange factor 3 1 107571160-107965144 Predicted intracellular proteins Evidence at protein level CAB002012 Uncertain Renal cancer:4.60e-8 (favourable) Expressed in all Tissue enhanced kidney: 90.9 skin: 58.7 Cell line enhanced REH: 48.1;RH-30: 60.2;RPTEC TERT1: 66.0;T-47d: 100.9 +CHIA AMCase, CHIT2, TSA1902 ENSG00000134216 Chitinase, acidic 1 111290862-111320566 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059193 Approved Tissue enhanced Group enriched 11 lung: 15.6;stomach: 8.2 endometrium: 1.1 Cell line enhanced ASC diff: 1.1 +PSRC1 DDA3 ENSG00000134222 Proline and serine rich coiled-coil 1 1 109279556-109283186 Predicted intracellular proteins Evidence at protein level HPA049315, HPA056561 Approved Approved Nucleoplasm
Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.36e-9 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 36.6 testis: 14.0 Expressed in all +HMGCS2 ENSG00000134240 3-hydroxy-3-methylglutaryl-CoA synthase 2 1 119747996-119768905 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027423, HPA027442, CAB032906 Enhanced Supported Mitochondria Liver cancer:2.43e-7 (favourable), Renal cancer:3.43e-5 (favourable), Ovarian cancer:2.17e-4 (favourable) Tissue enhanced Tissue enhanced liver: 1270.5 colon: 363.4 Cell line enriched 15 RT4: 161.6 +PTPN22 Lyp, Lyp1, Lyp2, PTPN8 ENSG00000134242 Protein tyrosine phosphatase, non-receptor type 22 1 113813811-113871759 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004912, CAB012209, HPA013350 Approved Uncertain Nucleoplasm
Vesicles
Plasma membrane Mixed Tissue enhanced bone marrow: 24.8 lymph node: 23.3 Cell line enhanced Daudi: 49.5;U-698: 25.4 +SORT1 Gp95, NT3 ENSG00000134243 Sortilin 1 1 109309568-109397951 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006889, CAB011498 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Colorectal cancer:7.74e-6 (favourable), Liver cancer:1.23e-4 (unfavourable) Expressed in all Expressed in all epididymis: 169.5 Mixed +WNT2B WNT13, XWNT2 ENSG00000134245 Wnt family member 2B 1 112466541-112530165 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047274, HPA060696, HPA066368 Uncertain Approved Nucleoplasm
Vesicles Tissue enhanced Mixed seminal vesicle: 20.0 Cell line enhanced HSkMC: 6.3 +PTGFRN CD315, CD9P-1, EWI-F, FLJ11001, FPRP, KIAA1436, SMAP-6 ENSG00000134247 Prostaglandin F2 receptor inhibitor 1 116910057-116990358 CD markers, Predicted membrane proteins Evidence at protein level HPA017074 Approved Renal cancer:3.98e-4 (unfavourable) Expressed in all Mixed smooth muscle: 69.3 Cell line enhanced U-87 MG: 146.9 +LAMTOR5 HBXIP, MGC71071, XIP ENSG00000134248 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 1 110401249-110407942 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006812 Approved Supported Cytosol Liver cancer:2.60e-4 (unfavourable), Thyroid cancer:5.52e-4 (favourable), Ovarian cancer:7.23e-4 (favourable) Expressed in all Expressed in all kidney: 431.6 Expressed in all +ADAM30 svph4 ENSG00000134249 ADAM metallopeptidase domain 30 1 119893533-119896495 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA026080 Uncertain Not detected Tissue enriched 471 testis: 47.0 all non-specific tissues: 0.0 Not detected +NOTCH2 ENSG00000134250 Notch 2 1 119911553-120069626 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048743 Approved Supported Nucleoplasm
Plasma membrane Ovarian cancer:5.24e-4 (unfavourable), Pancreatic cancer:9.48e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 46.7 Mixed +TRIM45 FLJ13181, RNF99 ENSG00000134253 Tripartite motif containing 45 1 117111060-117122587 Predicted intracellular proteins Evidence at protein level HPA030266, HPA054308 Uncertain Supported Cytokinetic bridge
Cytosol Breast cancer:1.58e-4 (favourable), Thyroid cancer:2.92e-4 (unfavourable) Expressed in all Mixed fallopian tube: 14.4 Cell line enhanced RH-30: 30.6 +CEPT1 ENSG00000134255 Choline/ethanolamine phosphotransferase 1 1 111139627-111185102 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level Glioma:6.43e-4 (favourable) Expressed in all Expressed in all spleen: 37.1 Expressed in all +CD101 IGSF2, V7 ENSG00000134256 CD101 molecule 1 117001750-117036476 CD markers, Predicted membrane proteins Evidence at protein level HPA049527, HPA057763 Approved Uncertain Mitochondria Mixed Tissue enhanced lung: 9.6 small intestine: 6.8 Cell line enriched 8 HMC-1: 24.0 +VTCN1 B7-H4, B7H4, B7S1, B7X, FLJ22418 ENSG00000134258 V-set domain containing T-cell activation inhibitor 1 1 117143587-117210960 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054200 Approved Approved Plasma membrane
Cell Junctions
Focal adhesion sites Group enriched Tissue enhanced breast: 129.4;fallopian tube: 51.3 cervix, uterine: 22.0 Group enriched 8 BEWO: 43.1;SK-BR-3: 182.1 +NGF NGFB ENSG00000134259 Nerve growth factor 1 115285918-115338236 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Renal cancer:8.08e-7 (unfavourable), Head and neck cancer:1.80e-4 (unfavourable) Mixed Tissue enhanced ovary: 12.3 smooth muscle: 5.9 Cell line enhanced BJ: 73.7;BJ hTERT+ SV40 Large T+: 28.4;hTEC/SVTERT24-B: 29.7;U-2197: 55.6 +AP4B1 BETA-4, SPG47 ENSG00000134262 Adaptor related protein complex 4 beta 1 subunit 1 113894748-113905201 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028162, HPA028652 Approved Approved Vesicles Liver cancer:8.60e-7 (unfavourable), Renal cancer:3.73e-6 (unfavourable) Expressed in all Expressed in all spleen: 19.2 Expressed in all +NAPG ENSG00000134265 NSF attachment protein gamma 18 10525905-10552761 Predicted intracellular proteins Evidence at protein level HPA008208, HPA011389 Enhanced Approved Plasma membrane
Cytosol Renal cancer:8.14e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 50.5 Expressed in all +SPIRE1 KIAA1135, spir-1 ENSG00000134278 Spire type actin nucleation factor 1 18 12446512-12658134 Predicted intracellular proteins Evidence at protein level HPA040737, HPA040942 Uncertain Approved Nucleoplasm
Cytosol Endometrial cancer:2.07e-4 (unfavourable), Stomach cancer:7.92e-4 (unfavourable) Expressed in all Tissue enhanced testis: 61.3 cerebral cortex: 50.4 Mixed +PPHLN1 ENSG00000134283 Periphilin 1 12 42238447-42459715 Predicted intracellular proteins Evidence at protein level HPA038902, HPA038903 Enhanced Enhanced Nucleoplasm
Golgi apparatus Liver cancer:1.28e-7 (unfavourable), Renal cancer:5.06e-5 (unfavourable) Expressed in all Expressed in all testis: 102.1 Expressed in all +FKBP11 FKBP19 ENSG00000134285 FK506 binding protein 11 12 48921518-48926474 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA041709 Enhanced Approved Centrosome Renal cancer:0.00e+0 (unfavourable), Endometrial cancer:7.09e-4 (favourable) Expressed in all Mixed pancreas: 60.7 Mixed +ARF3 ENSG00000134287 ADP ribosylation factor 3 12 48935723-48957551 Plasma proteins, Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all cerebral cortex: 402.7 Expressed in all +TMEM106C MGC5576 ENSG00000134291 Transmembrane protein 106C 12 47963569-47968878 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047204 Enhanced Liver cancer:5.27e-8 (unfavourable), Renal cancer:4.62e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 169.3 Expressed in all +SLC38A2 ATA2, KIAA1382, SAT2, SNAT2 ENSG00000134294 Solute carrier family 38 member 2 12 46358189-46372867 Predicted membrane proteins Evidence at protein level HPA035180 Approved Approved Vesicles Expressed in all Expressed in all skin: 238.8 Mixed +YWHAQ 14-3-3, HS1 ENSG00000134308 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta 2 9583972-9631014 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007925, CAB010286 Approved Supported Nucleoplasm
Cytosol Liver cancer:9.83e-6 (unfavourable), Endometrial cancer:8.20e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 398.1 Expressed in all +KIDINS220 ARMS ENSG00000134313 Kinase D interacting substrate 220 2 8721081-8837630 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014790 Supported Approved Nucleoplasm Renal cancer:9.29e-6 (favourable), Lung cancer:9.64e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 101.6 Expressed in all +GRHL1 LBP-32, MGR, TFCP2L2 ENSG00000134317 Grainyhead like transcription factor 1 2 9951693-10002277 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005798, HPA006420 Enhanced Enhanced Nucleus
Golgi apparatus
Vesicles Mixed Tissue enhanced esophagus: 111.4;skin: 106.8 parathyroid gland: 50.3 Cell line enhanced BEWO: 205.8;SK-BR-3: 84.4 +ROCK2 ENSG00000134318 Rho associated coiled-coil containing protein kinase 2 2 11179761-11348330 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007459, CAB008666, HPA044109 Approved Supported Cytosol Renal cancer:1.57e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 41.0 Expressed in all +RSAD2 cig5, vig1, viperin ENSG00000134321 Radical S-adenosyl methionine domain containing 2 2 6865806-6898239 Predicted intracellular proteins Evidence at protein level HPA041160, HPA049409 Approved Supported Nucleoli fibrillar center
Endoplasmic reticulum Endometrial cancer:4.60e-4 (unfavourable) Expressed in all Mixed spleen: 17.6 Cell line enhanced BJ hTERT+ SV40 Large T+: 75.1;BJ hTERT+ SV40 Large T+ RasG12V: 120.3;HMC-1: 51.2 +MYCN bHLHe37, MYCNOT, N-myc, NMYC ENSG00000134323 V-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2 15940564-15947007 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057420 Approved Nucleus
Nucleoli Tissue enhanced Tissue enhanced placenta: 13.7 cerebral cortex: 7.2 Cell line enhanced AF22: 43.5;BEWO: 230.1;HMC-1: 50.4;NTERA-2: 91.1;RH-30: 61.3 +LPIN1 KIAA0188 ENSG00000134324 Lipin 1 2 11677595-11827409 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038021 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all Expressed in all testis: 102.1 Expressed in all +CMPK2 NDK, TYKi, UMP-CMPK2 ENSG00000134326 Cytidine/uridine monophosphate kinase 2 2 6840570-6866635 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041430 Approved Approved Mitochondria Endometrial cancer:4.71e-4 (unfavourable) Expressed in all Mixed spleen: 5.5 Cell line enhanced BJ hTERT+ SV40 Large T+: 16.8;BJ hTERT+ SV40 Large T+ RasG12V: 15.8;HEL: 23.9;MOLT-4: 11.9 +IAH1 ENSG00000134330 Isoamyl acetate-hydrolyzing esterase 1 homolog 2 9473658-9496543 Predicted intracellular proteins Evidence at protein level HPA040523 Supported Nucleoplasm Renal cancer:3.64e-4 (unfavourable) Expressed in all Expressed in all testis: 121.2 Mixed +LDHA ENSG00000134333 Lactate dehydrogenase A 11 18394388-18408425 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB015336, CAB069404 Uncertain Supported Vesicles
Cytosol Renal cancer:9.69e-9 (unfavourable), Liver cancer:3.26e-8 (unfavourable), Lung cancer:2.27e-6 (unfavourable), Pancreatic cancer:8.09e-6 (unfavourable), Cervical cancer:2.78e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 503.4 Expressed in all +SAA2 ENSG00000134339 Serum amyloid A2 11 18239223-18248643 Disease related genes, Predicted secreted proteins Evidence at protein level Renal cancer:1.30e-8 (unfavourable) Tissue enriched Tissue enhanced adipose tissue: 713.3;cervix, uterine: 414.7;liver: 581.2 appendix: 211.6 Cell line enhanced A-431: 25.4;EFO-21: 20.0;HaCaT: 23.6;HBEC3-KT: 41.5 +ANO3 C11orf25, DYT23, GENX-3947, TMEM16C ENSG00000134343 Anoctamin 3 11 26309599-26663288 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041629 Uncertain Not detected Tissue enriched 6 epididymis: 62.2 cerebral cortex: 10.5 Cell line enhanced HDLM-2: 5.9;U-2 OS: 1.7;U-2197: 4.2 +IL6ST CD130, GP130 ENSG00000134352 Interleukin 6 signal transducer 5 55935095-55994993 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010558, CAB025784 Uncertain Supported Golgi apparatus
Plasma membrane Renal cancer:5.05e-4 (unfavourable) Expressed in all Expressed in all placenta: 329.8 Expressed in all +FST FS ENSG00000134363 Follistatin 5 53480409-53487134 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026025 Approved Renal cancer:4.44e-5 (unfavourable) Expressed in all Mixed liver: 33.0 Cell line enhanced BJ hTERT+: 272.8;HaCaT: 253.0;PC-3: 509.0 +CFHR4 CFHL4, FHR-4, FHR4 ENSG00000134365 Complement factor H related 4 1 196850241-196918972 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Liver cancer:1.57e-6 (favourable) Tissue enriched Tissue enriched 373 liver: 78.3 testis: 0.2 Cell line enhanced U-266/70: 1.1 +NAV1 DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1 ENSG00000134369 Neuron navigator 1 1 201622885-201826969 Predicted intracellular proteins Evidence at protein level CAB012302, HPA018127, HPA027887 Enhanced Approved Microtubules Renal cancer:3.10e-6 (unfavourable) Mixed Mixed cerebral cortex: 31.8 Cell line enhanced TIME: 153.0 +CDC73 C1orf28, FIHP, HRPT1, HRPT2, parafibromin ENSG00000134371 Cell division cycle 73 1 193122017-193253901 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016359, HPA030772 Enhanced Supported Nucleus
Cytosol Expressed in all Expressed in all thyroid gland: 32.2 Expressed in all +TIMM17A TIM17, TIM17A ENSG00000134375 Translocase of inner mitochondrial membrane 17A 1 201955491-201970661 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA010083 Approved Supported Nucleoplasm
Mitochondria Breast cancer:1.98e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 63.2 Expressed in all +CRB1 LCA8, RP12 ENSG00000134376 Crumbs 1, cell polarity complex component 1 197268204-197478455 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA061250, HPA063127 Approved Uncertain Vesicles Tissue enriched Group enriched 10 cerebral cortex: 12.2;testis: 5.0 ovary: 0.8 Cell line enriched 5 HeLa: 9.0 +CFHR5 CFHL5, FHR-5, FHR5 ENSG00000134389 Complement factor H related 5 1 196977556-197009674 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA038915, HPA040726 Supported Tissue enriched Tissue enriched 500 liver: 88.0 testis: 0.1 Not detected +ERN2 IRE1b ENSG00000134398 Endoplasmic reticulum to nucleus signaling 2 16 23690326-23713500 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA016558 Uncertain Mixed Group enriched 7 cervix, uterine: 27.6;colon: 27.5;duodenum: 12.3;gallbladder: 25.1;rectum: 23.2;small intestine: 9.9;stomach: 49.1 appendix: 3.8 Cell line enriched 8 CAPAN-2: 5.9 +RPS15A S15A ENSG00000134419 Ribosomal protein S15a 16 18781295-18790383 Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins Evidence at protein level HPA047103 Supported Renal cancer:7.29e-7 (unfavourable) Expressed in all Expressed in all breast: 4784.5 Expressed in all +RAX RX ENSG00000134438 Retina and anterior neural fold homeobox 18 59267035-59274086 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Not detected prostate: 0.2 Cell line enhanced HMC-1: 1.6;SH-SY5Y: 1.0 +NARS NARS1 ENSG00000134440 Asparaginyl-tRNA synthetase 18 57600656-57622213 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034257, HPA040017 Enhanced Approved Cytosol Liver cancer:1.23e-7 (unfavourable), Renal cancer:1.73e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 154.1 Expressed in all +GRP ENSG00000134443 Gastrin releasing peptide 18 59220168-59230774 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced lung: 13.4;thyroid gland: 10.4 parathyroid gland: 3.9 Group enriched 8 BJ hTERT+: 4.2;fHDF/TERT166: 5.1 +KIAA1468 FLJ33841, HsT3308, HsT885 ENSG00000134444 KIAA1468 18 62187258-62307829 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039708, HPA040038 Approved Approved Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all Expressed in all skin: 24.6 Expressed in all +FBXO18 FBH1, Fbx18, FLJ14590 ENSG00000134452 F-box protein, helicase, 18 10 5890203-5937594 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA002844 Supported Liver cancer:7.73e-7 (unfavourable) Expressed in all Expressed in all fallopian tube: 46.8 Expressed in all +RBM17 MGC14439, SPF45 ENSG00000134453 RNA binding motif protein 17 10 6088987-6117457 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037477, HPA037478 Supported Supported Nucleoplasm Liver cancer:4.57e-8 (unfavourable), Renal cancer:4.31e-5 (unfavourable) Expressed in all Expressed in all placenta: 104.6 Expressed in all +IL2RA CD25, IDDM10, IL2R ENSG00000134460 Interleukin 2 receptor subunit alpha 10 6010689-6062325 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002419, HPA054622 Enhanced Renal cancer:2.08e-9 (unfavourable) Mixed Tissue enhanced adipose tissue: 24.2;appendix: 19.8;lymph node: 20.4 tonsil: 12.0 Cell line enriched 80 HDLM-2: 1041.6 +ANKRD16 DKFZP434N1511 ENSG00000134461 Ankyrin repeat domain 16 10 5861617-5889906 Predicted intracellular proteins Evidence at protein level HPA037920, HPA037921 Uncertain Approved Endoplasmic reticulum Renal cancer:4.31e-7 (unfavourable), Pancreatic cancer:1.98e-4 (favourable) Expressed in all Mixed testis: 9.9 Expressed in all +ECHDC3 FLJ20909 ENSG00000134463 Enoyl-CoA hydratase domain containing 3 10 11742366-11764070 Predicted intracellular proteins Evidence at protein level HPA038306 Enhanced Approved Nucleus
Nucleoli
Mitochondria Renal cancer:3.43e-4 (favourable), Urothelial cancer:3.91e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 76.6 Cell line enhanced A-431: 46.0;BEWO: 27.7 +IL15RA CD215, IL-15RA ENSG00000134470 Interleukin 15 receptor subunit alpha 10 5943639-5978187 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB026215 Approved Uncertain Plasma membrane
Cytosol Renal cancer:1.27e-12 (unfavourable), Liver cancer:2.67e-6 (unfavourable), Pancreatic cancer:5.35e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 33.5 Cell line enhanced CAPAN-2: 59.4;HDLM-2: 70.4 +CCNH CycH, p34, p37 ENSG00000134480 Cyclin H 5 87391494-87413019 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB019416, HPA044138 Approved Supported Nucleoplasm Renal cancer:3.92e-5 (unfavourable), Ovarian cancer:4.35e-4 (unfavourable) Expressed in all Expressed in all testis: 88.4 Expressed in all +HRH4 AXOR35, GPCR105, GPRv53, H4R, HH4R ENSG00000134489 Histamine receptor H4 18 24460629-24479957 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA035009 Uncertain Not detected Not detected skin: 0.7 Cell line enhanced HL-60: 1.1 +TMEM241 C18orf45, FLJ44259, MGC11386 ENSG00000134490 Transmembrane protein 241 18 23197144-23437961 Predicted membrane proteins Evidence at protein level HPA029489, HPA059922 Uncertain Approved Golgi apparatus
Vesicles Urothelial cancer:5.80e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 4.2 Mixed +KCTD1 C18orf5 ENSG00000134504 Potassium channel tetramerization domain containing 1 18 26454910-26657401 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.60e-8 (favourable), Endometrial cancer:2.22e-4 (unfavourable) Expressed in all Mixed fallopian tube: 72.7 Cell line enhanced AF22: 101.7;HaCaT: 97.2 +CABLES1 FLJ35924, HsT2563 ENSG00000134508 Cdk5 and Abl enzyme substrate 1 18 23134564-23260467 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA073649 Supported Nucleus
Nuclear bodies Renal cancer:4.71e-6 (favourable) Tissue enriched Tissue enhanced parathyroid gland: 60.1 lung: 32.2 Cell line enhanced SK-MEL-30: 120.1;U-266/70: 164.7 +DOCK2 KIAA0209 ENSG00000134516 Dedicator of cytokinesis 2 5 169637247-170083382 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036469 Enhanced Expressed in all Mixed lymph node: 52.1 Cell line enhanced Daudi: 87.0;HDLM-2: 143.2;HL-60: 97.8;HMC-1: 119.0 +EMP1 CL-20, TMP ENSG00000134531 Epithelial membrane protein 1 12 13196716-13219939 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051931, HPA056250 Approved Nucleoplasm Ovarian cancer:2.26e-8 (unfavourable), Urothelial cancer:9.69e-8 (unfavourable), Pancreatic cancer:7.46e-4 (unfavourable) Expressed in all Expressed in all esophagus: 2199.3 Cell line enhanced ASC TERT1: 819.4 +SOX5 L-SOX5, MGC35153 ENSG00000134532 SRY-box 5 12 23529500-23951032 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060499 Supported Nucleoplasm Mixed Tissue enhanced testis: 58.4 cerebral cortex: 11.7 Cell line enhanced AF22: 14.4;HDLM-2: 25.3;K-562: 15.1;WM-115: 13.9 +RERG MGC15754 ENSG00000134533 RAS like estrogen regulated growth inhibitor 12 15107783-15348675 Predicted intracellular proteins Evidence at protein level HPA041387 Approved Endometrial cancer:7.56e-4 (unfavourable) Expressed in all Tissue enhanced endometrium: 141.5 smooth muscle: 125.5 Group enriched 5 AN3-CA: 14.0;BEWO: 32.9;T-47d: 62.0;U-2 OS: 22.6 +SLCO1B1 LST-1, OATP-C, OATP1B1, SLC21A6 ENSG00000134538 Solute carrier organic anion transporter family member 1B1 12 21131202-21239246 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA050892 Supported Tissue enriched Tissue enriched 248 liver: 308.0 breast: 1.2 Not detected +KLRD1 CD94 ENSG00000134539 Killer cell lectin like receptor D1 12 10226058-10329600 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA069688 Uncertain Mixed Tissue enhanced spleen: 18.8 lymph node: 6.7 Mixed +KLRC1 CD159a, NKG2, NKG2-A, NKG2-B ENSG00000134545 Killer cell lectin like receptor C1 12 10442264-10454685 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058052 Approved Plasma membrane Mixed Mixed spleen: 9.9 Cell line enhanced HeLa: 3.5 +SPX C12orf39, MGC10946, NPQ, spexin ENSG00000134548 Spexin hormone 12 21526307-21537377 Predicted secreted proteins Evidence at protein level Renal cancer:1.31e-6 (favourable) Tissue enhanced Group enriched 6 adipose tissue: 53.7;placenta: 13.5 thyroid gland: 6.1 Cell line enhanced CACO-2: 11.2;HBEC3-KT: 4.9;hTERT-HME1: 6.9;U-2 OS: 4.4 +PRH2 Pr ENSG00000134551 Proline rich protein HaeIII subfamily 2 12 10929236-10932341 Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 1858 salivary gland: 16591.4 ovary: 8.9 Not detected +LRP4 CLSS, LRP-4, MEGF7, SOST2 ENSG00000134569 LDL receptor related protein 4 11 46856868-46918642 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011934, HPA012300 Approved Uncertain Nucleus
Nucleoli
Mitochondria Expressed in all Tissue enhanced cerebral cortex: 35.4;skin: 37.9 parathyroid gland: 13.1 Cell line enhanced AF22: 21.2 +MYBPC3 CMH4, FHC, MYBP-C ENSG00000134571 Myosin binding protein C, cardiac 11 47331397-47352702 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040147, HPA043898 Enhanced Not detected Tissue enriched 496 heart muscle: 711.2 testis: 1.4 Cell line enriched 15 U-937: 4.9 +DDB2 DDBB, FLJ34321, UV-DDB2, XPE ENSG00000134574 Damage specific DNA binding protein 2 11 47214465-47239240 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB025912, HPA058406 Enhanced Supported Nucleoplasm
Cell Junctions Endometrial cancer:1.20e-4 (favourable), Cervical cancer:1.58e-4 (favourable), Breast cancer:7.29e-4 (favourable) Expressed in all Expressed in all skin: 53.7 Expressed in all +ACP2 LAP ENSG00000134575 Acid phosphatase 2, lysosomal 11 47239302-47248906 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Endometrial cancer:1.04e-4 (favourable) Expressed in all Expressed in all duodenum: 41.2 Expressed in all +USP26 ENSG00000134588 Ubiquitin specific peptidase 26 X 133024631-133097109 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 7 testis: 1.1 bone marrow,breast,endometrium,epididymis,gallbladder,lymph node,prostate,skin,spleen,thyroid gland: 0.1 Not detected +FAM127A CXX1, Mar8, MAR8C, Mart8 ENSG00000134590 Family with sequence similarity 127 member A X 135032366-135033546 Predicted intracellular proteins Evidence at protein level Pancreatic cancer:1.97e-4 (favourable), Endometrial cancer:2.69e-4 (unfavourable), Liver cancer:5.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 240.4 Mixed +RAB33A RabS10 ENSG00000134594 RAB33A, member RAS oncogene family X 130171649-130184870 Predicted intracellular proteins Evidence at protein level HPA059737 Uncertain Approved Vesicles Group enriched Tissue enhanced cerebral cortex: 31.9 lymph node: 9.1 Cell line enhanced HMC-1: 70.4;Karpas-707: 65.9;U-266/70: 50.9 +SOX3 PHP ENSG00000134595 SRY-box 3 X 140502985-140505116 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054720, HPA075003 Enhanced Nucleoplasm Tissue enhanced Tissue enriched 7 fallopian tube: 14.2 testis: 2.0 Group enriched 11 AF22: 7.2;HEK 293: 7.2;NTERA-2: 17.4 +RBMX2 CGI-79, Snu17 ENSG00000134597 RNA binding motif protein, X-linked 2 X 130401969-130413343 Predicted intracellular proteins Evidence at protein level HPA026609 Approved Approved Nuclear membrane
Nucleoli Renal cancer:8.44e-9 (unfavourable), Liver cancer:7.04e-4 (unfavourable), Lung cancer:9.15e-4 (favourable) Expressed in all Expressed in all endometrium: 29.4 Expressed in all +STK26 MASK, MST4 ENSG00000134602 Serine/threonine kinase 26 X 132023265-132075943 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059921 Approved Approved Nucleus
Golgi apparatus
Centrosome
Cytosol Renal cancer:6.87e-5 (unfavourable), Liver cancer:6.82e-4 (unfavourable) Expressed in all Mixed epididymis: 68.5 Mixed +PIWIL4 FLJ36156, HIWI2, Miwi2 ENSG00000134627 Piwi like RNA-mediated gene silencing 4 11 94543840-94621421 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036587, HPA036588, HPA057508 Enhanced Approved Nucleus
Mitochondria Mixed Tissue enhanced testis: 24.3 bone marrow: 15.5 Cell line enhanced NB-4: 58.5;THP-1: 13.6 +MTNR1B ENSG00000134640 Melatonin receptor 1B 11 92969720-92985066 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced placenta: 1.4 testis: 0.8 Not detected +PUM1 KIAA0099, PUMH1 ENSG00000134644 Pumilio RNA binding family member 1 1 30931506-31065991 Predicted intracellular proteins Evidence at protein level HPA027424, HPA027449 Approved Supported Nucleus
Cytosol Renal cancer:7.62e-8 (favourable), Liver cancer:3.73e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 73.0 Expressed in all +SPOCD1 FLJ25348, PPP1R146 ENSG00000134668 SPOC domain containing 1 1 31790422-31816051 Predicted intracellular proteins Evidence at protein level HPA031713, HPA031714, HPA031715 Enhanced Approved Nucleus
Nucleoli
Cytosol Urothelial cancer:4.05e-5 (favourable) Group enriched Tissue enhanced testis: 14.1;urinary bladder: 10.0 appendix: 4.4 Cell line enhanced hTEC/SVTERT24-B: 51.5;RT4: 71.0;U-87 MG: 82.7 +YARS tyrRS, YRS, YTS ENSG00000134684 Tyrosyl-tRNA synthetase 1 32775237-32818153 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017936, HPA018950, HPA018954 Enhanced Enhanced Cytosol Renal cancer:1.02e-11 (unfavourable), Liver cancer:6.97e-11 (unfavourable), Urothelial cancer:6.57e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 81.5 Expressed in all +PHC2 EDR2, HPH2 ENSG00000134686 Polyhomeotic homolog 2 1 33323623-33431052 Predicted intracellular proteins Evidence at protein level HPA047403 Supported Supported Nucleoplasm Liver cancer:2.28e-6 (unfavourable), Renal cancer:2.35e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 88.1 Expressed in all +CDCA8 BOR, DasraB, FLJ12042, MESRGP ENSG00000134690 Cell division cycle associated 8 1 37692418-37709719 Predicted intracellular proteins Evidence at protein level HPA028120, HPA028258, HPA028783, CAB040294 Enhanced Supported Nucleus
Nucleoli
Cytokinetic bridge Renal cancer:0.00e+0 (unfavourable), Liver cancer:4.93e-10 (unfavourable), Melanoma:6.04e-4 (unfavourable), Pancreatic cancer:8.32e-4 (unfavourable) Expressed in all Tissue enhanced testis: 36.5 lymph node: 23.0 Mixed +GNL2 HUMAUANTIG, Ngp-1, Nog2, Nug2 ENSG00000134697 G protein nucleolar 2 1 37566816-37595935 Predicted intracellular proteins Evidence at protein level HPA027163, HPA060026 Approved Enhanced Nucleoli Renal cancer:2.90e-11 (unfavourable), Liver cancer:5.86e-9 (unfavourable), Ovarian cancer:7.89e-4 (favourable) Expressed in all Expressed in all testis: 55.6 Expressed in all +AGO4 EIF2C4, FLJ20033, hAGO4, KIAA1567 ENSG00000134698 Argonaute 4, RISC catalytic component 1 35808172-35857890 Predicted intracellular proteins Evidence at protein level CAB012179, HPA068896 Approved Enhanced Nucleoplasm
Nuclear bodies
Cytosol Head and neck cancer:5.70e-5 (favourable) Expressed in all Expressed in all skin: 24.4 Mixed +HOOK1 HK1 ENSG00000134709 Hook microtubule tethering protein 1 1 59814786-59876378 Predicted intracellular proteins Evidence at protein level HPA018537, HPA018820 Enhanced Colorectal cancer:4.53e-6 (favourable), Head and neck cancer:4.42e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 55.2 testis: 30.1 Cell line enhanced EFO-21: 32.6;RPTEC TERT1: 24.3 +CYP2J2 ENSG00000134716 Cytochrome P450 family 2 subfamily J member 2 1 59893308-59926790 Enzymes, Predicted secreted proteins Evidence at protein level Renal cancer:5.54e-7 (unfavourable) Mixed Tissue enhanced liver: 74.4;small intestine: 92.3 heart muscle: 57.5 Cell line enhanced RT4: 48.3;SK-BR-3: 12.0 +BTF3L4 MGC23908 ENSG00000134717 Basic transcription factor 3 like 4 1 52056125-52090716 Predicted intracellular proteins Evidence at protein level HPA067026 Approved Approved Nucleus
Cytosol Liver cancer:6.73e-8 (unfavourable), Renal cancer:4.43e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 72.6 Expressed in all +ZCCHC11 KIAA0191, PAPD3, TUT4 ENSG00000134744 Zinc finger CCHC-type containing 11 1 52408282-52553487 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027412, HPA027973 Supported Supported Nucleoli
Cytosol Liver cancer:9.00e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 59.8 Mixed +PRPF38A FLJ14936, Prp38 ENSG00000134748 Pre-mRNA processing factor 38A 1 52404564-52420839 Predicted intracellular proteins Evidence at protein level HPA053099, HPA058407 Uncertain Enhanced Nucleus Liver cancer:3.83e-5 (unfavourable), Renal cancer:7.41e-5 (unfavourable), Colorectal cancer:7.16e-4 (favourable) Expressed in all Expressed in all endometrium: 23.0 Expressed in all +DSC2 CDHF2, DSC3 ENSG00000134755 Desmocollin 2 18 31058840-31102415 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA011911, HPA012615 Enhanced Urothelial cancer:3.01e-4 (unfavourable), Lung cancer:5.80e-4 (unfavourable) Tissue enhanced Tissue enhanced esophagus: 186.7 parathyroid gland: 62.0 Cell line enhanced BEWO: 36.6;CAPAN-2: 44.0;HaCaT: 63.9;hTCEpi: 55.4;SK-BR-3: 33.9 +DSG3 CDHF6 ENSG00000134757 Desmoglein 3 18 31447795-31478702 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA046864, HPA056863, CAB069880 Enhanced Pancreatic cancer:1.43e-5 (unfavourable), Urothelial cancer:9.90e-4 (unfavourable) Group enriched Tissue enriched 5 esophagus: 349.5 tonsil: 66.0 Group enriched 7 HaCaT: 182.7;hTCEpi: 362.3 +RNF138 NARF, STRIN ENSG00000134758 Ring finger protein 138 18 32091855-32131561 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041101 Approved Mitochondria Expressed in all Expressed in all testis: 167.7 Expressed in all +ELP2 FLJ10879, STATIP1, StIP ENSG00000134759 Elongator acetyltransferase complex subunit 2 18 36129444-36180556 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002996, CAB020835 Approved Supported Nucleus
Nuclear bodies
Cytosol Colorectal cancer:5.41e-4 (favourable) Expressed in all Expressed in all ovary: 59.6 Expressed in all +DSG1 CDHF4, DSG ENSG00000134760 Desmoglein 1 18 31318089-31357029 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009394, HPA022128 Enhanced Urothelial cancer:2.99e-4 (unfavourable) Group enriched Tissue enriched 20 skin: 725.7 esophagus: 36.4 Cell line enriched 17 hTCEpi: 6.6 +DSC3 CDHF3, DSC, DSC1, DSC2, DSC4 ENSG00000134762 Desmocollin 3 18 30990008-31042815 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB037328, HPA049265, HPA073937 Enhanced Enhanced Plasma membrane
Cell Junctions Urothelial cancer:1.04e-5 (unfavourable) Tissue enhanced Group enriched 12 esophagus: 119.1;skin: 454.8 tonsil: 24.8 Cell line enhanced HaCaT: 242.4;hTCEpi: 115.0;hTERT-HME1: 89.5 +DSC1 CDHF1 ENSG00000134765 Desmocollin 1 18 31129236-31162856 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA075379 Enhanced Group enriched Tissue enriched 15 skin: 273.0 heart muscle: 17.8 Not detected +DTNA D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3 ENSG00000134769 Dystrobrevin alpha 18 34493290-34891844 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB015196, HPA071177 Enhanced Approved Nucleoplasm
Cell Junctions
Intermediate filaments Renal cancer:2.64e-7 (favourable) Tissue enriched Tissue enhanced cerebral cortex: 197.2 heart muscle: 101.8 Cell line enhanced NTERA-2: 42.7;SCLC-21H: 70.5;U-87 MG: 59.2 +FHOD3 FHOS2, FLJ22297, FLJ22717, KIAA1695 ENSG00000134775 Formin homology 2 domain containing 3 18 36297714-36780055 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021827, HPA024696 Uncertain Renal cancer:1.19e-5 (favourable) Mixed Tissue enhanced heart muscle: 96.5;seminal vesicle: 88.0 epididymis: 51.4 Cell line enhanced BJ hTERT+: 58.7;HDLM-2: 74.2 +TPGS2 C18orf10, DKFZP586M1523, HsT3006 ENSG00000134779 Tubulin polyglutamylase complex subunit 2 18 36777647-36829216 Predicted intracellular proteins Evidence at protein level HPA040596, HPA040617, HPA061753 Uncertain Supported Nucleoli Liver cancer:1.24e-5 (unfavourable), Ovarian cancer:1.93e-5 (favourable), Cervical cancer:4.09e-4 (favourable), Testis cancer:7.74e-4 (favourable) Expressed in all Expressed in all testis: 367.2 Expressed in all +DAGLA C11orf11, DAGLALPHA, KIAA0659, NSDDR ENSG00000134780 Diacylglycerol lipase alpha 11 61680433-61747001 Disease related genes, Predicted membrane proteins Evidence at protein level HPA062497 Approved Endometrial cancer:1.13e-7 (unfavourable) Expressed in all Tissue enriched 6 cerebral cortex: 18.6 colon,testis: 3.0 Mixed +SLC43A3 DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1 ENSG00000134802 Solute carrier family 43 member 3 11 57406954-57427580 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA030551, HPA077244 Approved Approved Nucleoplasm
Vesicles
Plasma membrane Renal cancer:3.97e-13 (unfavourable) Expressed in all Expressed in all thyroid gland: 122.3 Cell line enhanced WM-115: 524.5 +TIMM10 TIM10, TIM10A, TIMM10A ENSG00000134809 Translocase of inner mitochondrial membrane 10 11 57528463-57530803 Predicted intracellular proteins Evidence at protein level HPA039946 Enhanced Enhanced Mitochondria Expressed in all Expressed in all epididymis: 52.6 Expressed in all +GIF IF, IFMH, INF, TCN3 ENSG00000134812 Gastric intrinsic factor 11 59829268-59845501 Disease related genes, Predicted secreted proteins Evidence at protein level HPA039908, HPA040774 Enhanced Tissue enriched Tissue enriched 1701 stomach: 1311.7 cerebral cortex: 0.7 Not detected +DHX34 DDX34, KIAA0134 ENSG00000134815 DExH-box helicase 34 19 47349281-47382704 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042159, HPA043558 Uncertain Uncertain Nucleus
Intermediate filaments Renal cancer:3.16e-6 (unfavourable), Liver cancer:8.63e-6 (unfavourable) Expressed in all Mixed testis: 20.8 Expressed in all +APLNR AGTRL1, APJ, APJR, FLJ90771 ENSG00000134817 Apelin receptor 11 57233577-57237314 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level CAB025842 Approved Expressed in all Group enriched 5 cerebral cortex: 82.7;placenta: 146.8;spleen: 161.6 adipose tissue: 24.9 Group enriched 22 AF22: 6.2;HEL: 5.0;K-562: 1.5;NTERA-2: 1.8 +FADS2 D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13 ENSG00000134824 Fatty acid desaturase 2 11 61792980-61867354 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006741 Approved Renal cancer:1.00e-7 (unfavourable), Urothelial cancer:3.42e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 414.3 Expressed in all +TMEM258 C11orf10 ENSG00000134825 Transmembrane protein 258 11 61768501-61792802 Predicted membrane proteins Evidence at protein level HPA044602 Approved Approved Plasma membrane
Cytosol Ovarian cancer:4.37e-4 (favourable) Expressed in all Expressed in all epididymis: 437.6 Expressed in all +TCN1 TC1, TCI ENSG00000134827 Transcobalamin 1 11 59852800-59866575 Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.56e-8 (unfavourable), Breast cancer:1.90e-4 (favourable) Tissue enhanced Tissue enhanced bone marrow: 123.8;gallbladder: 254.4;salivary gland: 315.5 stomach: 75.5 Cell line enhanced CAPAN-2: 4.7;HaCaT: 4.6;PC-3: 6.4;SiHa: 7.7 +C5AR2 C5L2, GPR77 ENSG00000134830 Complement component 5a receptor 2 19 47332147-47347327 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA016629 Uncertain Tissue enhanced Tissue enhanced spleen: 9.7 appendix: 5.9 Group enriched 6 MCF7: 15.8;T-47d: 23.3 +TMEM165 GDT1, TMPT27, TPARL ENSG00000134851 Transmembrane protein 165 4 55395957-55453397 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA038299, HPA062424 Supported Enhanced Golgi apparatus
Vesicles Renal cancer:1.18e-8 (unfavourable), Liver cancer:2.08e-5 (unfavourable) Expressed in all Expressed in all placenta: 87.1 Expressed in all +CLOCK bHLHe8, KAT13D, KIAA0334 ENSG00000134852 Clock circadian regulator 4 55427903-55547138 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001867, HPA027565 Supported Enhanced Nucleoplasm Expressed in all Mixed testis: 26.4 Expressed in all +PDGFRA CD140a, GAS9, PDGFR2 ENSG00000134853 Platelet derived growth factor receptor alpha 4 54229097-54298247 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA004947, CAB018143 Supported Supported Nucleus
Plasma membrane
Cell Junctions Renal cancer:9.79e-6 (unfavourable), Head and neck cancer:9.33e-4 (favourable) Expressed in all Expressed in all ovary: 222.6 Cell line enhanced ASC diff: 306.3;ASC TERT1: 145.3;BJ hTERT+: 217.9;fHDF/TERT166: 147.1;HHSteC: 126.5;HSkMC: 276.0 +GGACT A2LD1 ENSG00000134864 Gamma-glutamylamine cyclotransferase 13 100530164-100589528 Enzymes, Predicted intracellular proteins Evidence at protein level HPA065320 Enhanced Expressed in all Tissue enriched 6 kidney: 75.9 testis: 11.8 Cell line enriched 8 SCLC-21H: 157.1 +COL4A2 DKFZp686I14213, FLJ22259 ENSG00000134871 Collagen type IV alpha 2 chain 13 110305812-110513027 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010751, HPA029118 Enhanced Supported Vesicles Renal cancer:3.49e-5 (unfavourable), Urothelial cancer:9.25e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 829.9 smooth muscle: 401.0 Cell line enhanced EFO-21: 1032.9;WM-115: 470.6 +CLDN10 CPETRL3, OSP-L ENSG00000134873 Claudin 10 13 95433604-95579759 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB012969, HPA042348 Enhanced Renal cancer:7.46e-5 (favourable), Thyroid cancer:2.13e-4 (favourable) Mixed Tissue enhanced kidney: 163.5 cervix, uterine: 112.6 Cell line enhanced EFO-21: 10.0;HUVEC TERT2: 11.9;NTERA-2: 28.0;RPTEC TERT1: 43.5 +DZIP1 DZIP, KIAA0996 ENSG00000134874 DAZ interacting zinc finger protein 1 13 95578202-95644703 Predicted intracellular proteins Evidence at protein level HPA054891, HPA057272, HPA070194 Uncertain Supported Nucleoplasm
Microtubule organizing center
Cytosol Mixed Tissue enhanced testis: 57.5 ovary: 30.4 Mixed +UBAC2 FLJ30548, PHGDHL1, RP11-178C10.1 ENSG00000134882 UBA domain containing 2 13 99200774-99386434 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013448 Approved Approved Cytosol Pancreatic cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 35.8 Expressed in all +ARGLU1 FLJ10154 ENSG00000134884 Arginine and glutamate rich 1 13 106541673-106568164 Predicted intracellular proteins Evidence at protein level HPA034962, HPA056792 Supported Enhanced Nucleoplasm
Mitochondria Pancreatic cancer:3.92e-5 (favourable), Urothelial cancer:7.34e-5 (favourable), Renal cancer:1.09e-4 (unfavourable) Expressed in all Expressed in all endometrium: 328.3 Expressed in all +BIVM FLJ20159 ENSG00000134897 Basic, immunoglobulin-like variable motif containing 13 102799049-102841535 Predicted intracellular proteins Evidence at transcript level HPA050126 Approved Approved Nucleoplasm Expressed in all Expressed in all kidney: 15.1 Mixed +ERCC5 ERCM2, XPGC ENSG00000134899 ERCC excision repair 5, endonuclease 13 102844844-102876001 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045845, HPA050374 Supported Supported Nucleoplasm Renal cancer:2.96e-6 (unfavourable), Urothelial cancer:6.82e-4 (favourable) Expressed in all Expressed in all lymph node: 16.4 Expressed in all +TPP2 TPPII ENSG00000134900 Tripeptidyl peptidase 2 13 102597003-102679958 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021069, HPA049630 Approved Supported Nuclear bodies
Cytosol Expressed in all Expressed in all testis: 66.8 Expressed in all +KDELC1 EP58, MGC5302 ENSG00000134901 KDEL motif containing 1 13 102784281-102799007 Predicted secreted proteins Evidence at protein level CAB020780, HPA043946, HPA064398 Approved Supported Nucleus Head and neck cancer:2.24e-4 (unfavourable), Renal cancer:4.73e-4 (unfavourable), Lung cancer:4.81e-4 (unfavourable) Expressed in all Mixed smooth muscle: 17.7 Mixed +CARS2 FLJ12118 ENSG00000134905 Cysteinyl-tRNA synthetase 2, mitochondrial (putative) 13 110641412-110713603 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041776 Uncertain Approved Nucleoplasm
Mitochondria Renal cancer:2.49e-5 (unfavourable), Liver cancer:1.21e-4 (unfavourable), Endometrial cancer:1.84e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 28.4 Expressed in all +ARHGAP32 GC-GAP, GRIT, KIAA0712, MGC1892, RICS ENSG00000134909 Rho GTPase activating protein 32 11 128965060-129279324 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA038382, HPA038389, HPA061505 Approved Approved Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus Pancreatic cancer:6.64e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 44.0 Mixed +STT3A ITM1, MGC9042, STT3-A, TMC ENSG00000134910 STT3A, catalytic subunit of the oligosaccharyltransferase complex 11 125591712-125625215 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA030735 Approved Uncertain Nucleoplasm
Vesicles
Cytosol Endometrial cancer:1.32e-4 (favourable), Liver cancer:3.57e-4 (unfavourable), Renal cancer:4.96e-4 (unfavourable) Expressed in all Tissue enriched 7 parathyroid gland: 1131.8 epididymis: 173.0 Expressed in all +ADAMTS8 ADAM-TS8, FLJ41712, METH2 ENSG00000134917 ADAM metallopeptidase with thrombospondin type 1 motif 8 11 130404925-130428993 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at transcript level HPA066349 Approved Endometrial cancer:1.38e-4 (favourable) Tissue enhanced Tissue enhanced appendix: 10.9;lung: 15.5 seminal vesicle: 5.5 Cell line enhanced HMC-1: 3.2;NTERA-2: 1.8;U-2 OS: 8.7 +ACRV1 D11S4365, SP-10, SPACA2 ENSG00000134940 Acrosomal vesicle protein 1 11 125671522-125681123 Predicted secreted proteins Evidence at protein level HPA038718, HPA038719 Enhanced Mixed Tissue enriched 40 testis: 153.6 epididymis: 3.8 Mixed +ETS1 ETS-1, EWSR2, FLJ10768 ENSG00000134954 ETS proto-oncogene 1, transcription factor 11 128458761-128587558 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level CAB002575, HPA063230 Enhanced Enhanced Nucleoplasm Renal cancer:1.30e-5 (unfavourable) Expressed in all Expressed in all lymph node: 320.7 Cell line enhanced U-698: 322.0 +SLC37A2 FLJ00171 ENSG00000134955 Solute carrier family 37 member 2 11 125063067-125090312 Predicted membrane proteins, Transporters Evidence at protein level HPA014948 Uncertain Expressed in all Mixed adrenal gland: 24.7 Cell line enhanced A-431: 23.5;CAPAN-2: 49.0;hTERT-HME1: 45.0;U-138 MG: 41.2 +KLB ENSG00000134962 Klotho beta 4 39406853-39451536 Predicted membrane proteins, Transporters Evidence at protein level HPA021136 Uncertain Tissue enriched Tissue enhanced adipose tissue: 20.6;liver: 9.1 testis: 5.0 Group enriched 19 ASC diff: 4.5;Hep G2: 17.2 +TMED7 CGI-109, FLJ90481, p24g3, p24gamma3 ENSG00000134970 Transmembrane p24 trafficking protein 7 5 115613508-115632992 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008960, CAB025883 Supported Expressed in all Expressed in all thyroid gland: 138.8 Expressed in all +APC DP2, DP2.5, DP3, PPP1R46 ENSG00000134982 APC, WNT signaling pathway regulator 5 112707498-112846239 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013349 Supported Expressed in all Tissue enhanced cerebral cortex: 60.1 parathyroid gland: 19.9 Expressed in all +NREP C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17 ENSG00000134986 Neuronal regeneration related protein 5 111662621-111997464 Predicted intracellular proteins Evidence at protein level HPA000545 Approved Approved Vesicles Stomach cancer:3.09e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 175.0 Cell line enhanced AF22: 411.4;SH-SY5Y: 475.7 +WDR36 GLC1G, TA-WDRP, UTP21 ENSG00000134987 WD repeat domain 36 5 111091716-111130502 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037796, HPA037797 Supported Supported Nucleoli Thyroid cancer:1.18e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 17.2 Expressed in all +OSTF1 bA235O14.1, OSF, SH3P2 ENSG00000134996 Osteoclast stimulating factor 1 9 75088543-75147265 Predicted intracellular proteins Evidence at protein level HPA020514 Approved Supported Cytosol Endometrial cancer:3.67e-5 (favourable) Expressed in all Expressed in all spleen: 122.7 Cell line enhanced HDLM-2: 286.9 +RFK FLJ11149, RIFK ENSG00000135002 Riboflavin kinase 9 76385517-76394517 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA023259, CAB033887, HPA057163 Approved Approved Golgi apparatus Expressed in all Expressed in all cerebral cortex: 37.8 Expressed in all +UBQLN1 DA41, DSK2, PLIC-1, XDRP1 ENSG00000135018 Ubiquilin 1 9 83659963-83708203 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037256, HPA054143 Supported Supported Nucleoplasm
Cytosol Renal cancer:1.07e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 113.8 Expressed in all +NAA35 bA379P1.1, FLJ21613, FLJ22643, MAK10 ENSG00000135040 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 9 85941146-86022298 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021547, HPA051586 Approved Supported Vesicles Liver cancer:1.16e-7 (unfavourable) Expressed in all Expressed in all testis: 37.9 Expressed in all +C9orf40 FLJ10110 ENSG00000135045 Chromosome 9 open reading frame 40 9 74946581-74952886 Predicted intracellular proteins Evidence at protein level HPA042167 Enhanced Approved Nucleoplasm
Centrosome
Cytosol Liver cancer:3.43e-4 (unfavourable) Expressed in all Mixed testis: 16.9 Mixed +ANXA1 ANX1, LPC1 ENSG00000135046 Annexin A1 9 73151757-73170393 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA011271, HPA011272, CAB013023, CAB035987, CAB058693 Enhanced Enhanced Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:6.19e-6 (unfavourable), Thyroid cancer:4.57e-5 (favourable), Endometrial cancer:5.71e-5 (favourable) Expressed in all Tissue enriched 6 esophagus: 7548.8 tonsil: 1217.6 Mixed +CTSL CTSL1, FLJ31037 ENSG00000135047 Cathepsin L 9 87725519-87731393 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000459 Enhanced Lung cancer:5.15e-5 (unfavourable), Renal cancer:4.34e-4 (favourable), Glioma:4.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 748.5 Cell line enhanced ASC TERT1: 1401.5 +TMEM2 ENSG00000135048 Transmembrane protein 2 9 71683366-71816690 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044889 Approved Approved Vesicles
Cytosol Renal cancer:1.31e-4 (unfavourable) Expressed in all Expressed in all placenta: 94.6 Cell line enhanced AF22: 107.2 +AGTPBP1 CCP1, KIAA1035, Nna1 ENSG00000135049 ATP/GTP binding protein 1 9 85546539-85742029 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA057208 Approved Approved Nucleoli
Vesicles Expressed in all Expressed in all bone marrow: 39.2 Expressed in all +GOLM1 bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73 ENSG00000135052 Golgi membrane protein 1 9 86026146-86100173 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA010638, HPA011929, CAB015341 Enhanced Enhanced Golgi apparatus Endometrial cancer:8.14e-5 (favourable), Liver cancer:1.30e-4 (unfavourable) Expressed in all Expressed in all stomach: 402.2 Mixed +FAM189A2 C9orf61, X123 ENSG00000135063 Family with sequence similarity 189 member A2 9 69324572-69392455 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029411, HPA057207 Approved Endometrial cancer:1.16e-6 (favourable), Renal cancer:1.75e-5 (favourable) Tissue enhanced Tissue enhanced thyroid gland: 101.0 cervix, uterine: 64.4 Cell line enhanced BEWO: 4.9;NTERA-2: 7.3;SK-MEL-30: 5.2 +PSAT1 PSA ENSG00000135069 Phosphoserine aminotransferase 1 9 78297143-78330093 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB014882, CAB040567, HPA042924 Enhanced Enhanced Cytosol Renal cancer:6.00e-7 (unfavourable), Endometrial cancer:5.62e-5 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 186.0 liver: 138.7 Cell line enhanced hTCEpi: 853.3 +ISCA1 HBLD2, hIscA, ISA1, MGC4276 ENSG00000135070 Iron-sulfur cluster assembly 1 9 86264546-86283102 Predicted intracellular proteins Evidence at protein level HPA042789 Uncertain Renal cancer:3.83e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 74.4 Expressed in all +ADAM19 MLTNB ENSG00000135074 ADAM metallopeptidase domain 19 5 157395534-157575775 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA055537 Approved Vesicles Renal cancer:3.90e-12 (unfavourable) Expressed in all Mixed lymph node: 34.4 Cell line enhanced HDLM-2: 101.7;U-251 MG: 170.3 +HAVCR2 CD366, FLJ14428, Tim-3, TIM3, TIMD3 ENSG00000135077 Hepatitis A virus cellular receptor 2 5 157085832-157142869 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB026003 Enhanced Expressed in all Mixed lung: 24.0 Cell line enhanced HDLM-2: 16.9;RPMI-8226: 10.3 +CCNJL FLJ14166 ENSG00000135083 Cyclin J like 5 160251652-160345396 Predicted intracellular proteins Evidence at protein level HPA049970 Approved Approved Nuclear speckles Thyroid cancer:7.10e-4 (favourable), Colorectal cancer:7.31e-4 (favourable), Urothelial cancer:8.02e-4 (favourable) Mixed Tissue enhanced testis: 19.4 lung: 10.3 Cell line enhanced HBEC3-KT: 46.5;WM-115: 45.6 +TAOK3 DPK, JIK, MAP3K18 ENSG00000135090 TAO kinase 3 12 118149801-118372945 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017160 Approved Uncertain Mitochondria Expressed in all Expressed in all cerebral cortex: 48.8 Expressed in all +USP30 FLJ40511, MGC10702 ENSG00000135093 Ubiquitin specific peptidase 30 12 109023089-109088026 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016952 Approved Renal cancer:5.23e-6 (favourable) Expressed in all Expressed in all testis: 25.4 Expressed in all +SDS SDH ENSG00000135094 Serine dehydratase 12 113392445-113426301 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039230 Uncertain Approved Mitochondria
Cytosol Cervical cancer:5.24e-4 (favourable) Tissue enriched Tissue enriched 18 liver: 189.8 cerebral cortex: 10.5 Cell line enhanced HMC-1: 1.5 +MSI1 ENSG00000135097 Musashi RNA binding protein 1 12 120341330-120369180 Predicted intracellular proteins Evidence at protein level HPA064401 Approved Nucleoplasm
Vesicles
Cytosol Pancreatic cancer:5.99e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 17.5;testis: 14.6 skeletal muscle: 7.2 Cell line enhanced AF22: 118.2;HAP1: 57.0;NTERA-2: 62.4;SCLC-21H: 104.1;SH-SY5Y: 45.6 +HNF1A HNF1, LFB1, MODY3, TCF1 ENSG00000135100 HNF1 homeobox A 12 120978543-121002512 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB010430, HPA035231 Enhanced Supported Nucleoplasm Mixed Tissue enhanced duodenum: 15.5;kidney: 10.6;small intestine: 15.7 liver: 6.3 Group enriched 7 A549: 8.0;CACO-2: 24.3;Hep G2: 22.1 +FBXO21 FBX21, KIAA0875 ENSG00000135108 F-box protein 21 12 117141988-117190531 Predicted intracellular proteins Evidence at protein level HPA062411, HPA071452 Approved Approved Mitochondria Renal cancer:2.05e-8 (favourable) Expressed in all Expressed in all fallopian tube: 204.6 Expressed in all +TBX3 TBX3-ISO, UMS, XHL ENSG00000135111 T-box 3 12 114670254-114684164 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005799 Approved Nucleoplasm
Cytosol Urothelial cancer:3.28e-4 (favourable) Expressed in all Tissue enhanced adrenal gland: 200.0 prostate: 119.8 Cell line enhanced BJ: 87.5;BJ hTERT+: 80.2;RT4: 103.3 +OASL p59OASL, TRIP14 ENSG00000135114 2'-5'-oligoadenylate synthetase like 12 121019111-121039242 Predicted intracellular proteins Evidence at protein level HPA001474 Approved Supported Nucleoplasm
Cytosol Renal cancer:3.70e-9 (unfavourable), Pancreatic cancer:9.20e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 35.4;stomach: 22.1 lung: 19.9 Cell line enhanced BJ hTERT+ SV40 Large T+: 131.5;BJ hTERT+ SV40 Large T+ RasG12V: 70.4;hTEC/SVTERT24-B: 56.8 +HRK DP5 ENSG00000135116 Harakiri, BCL2 interacting protein 12 116856144-116881441 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025973 Uncertain Mixed Group enriched 9 cerebral cortex: 13.3;thyroid gland: 6.4 testis: 1.1 Cell line enhanced Daudi: 7.9;SCLC-21H: 10.7;SH-SY5Y: 8.3;SK-MEL-30: 16.7;U-698: 25.7 +RNFT2 FLJ14627, TMEM118 ENSG00000135119 Ring finger protein, transmembrane 2 12 116738178-116853631 Predicted membrane proteins Evidence at protein level HPA064161 Enhanced Approved Nucleoplasm
Cytosol Mixed Tissue enhanced cerebral cortex: 15.3 testis: 6.0 Mixed +P2RX4 P2X4 ENSG00000135124 Purinergic receptor P2X 4 12 121209857-121234106 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA039494 Enhanced Approved Actin filaments
Cytosol Endometrial cancer:6.30e-10 (favourable) Expressed in all Mixed placenta: 33.8 Mixed +BICDL1 BICDR-1, CCDC64, FLJ26450 ENSG00000135127 BICD family like cargo adaptor 1 12 119989869-120094494 Predicted intracellular proteins Evidence at protein level HPA061116 Enhanced Approved Nucleoplasm
Vesicles
Cytosol Stomach cancer:1.21e-5 (favourable), Renal cancer:3.93e-5 (favourable), Head and neck cancer:3.15e-4 (favourable), Cervical cancer:6.50e-4 (favourable), Liver cancer:6.84e-4 (unfavourable) Expressed in all Tissue enhanced kidney: 73.9;skin: 58.6 epididymis: 45.6 Cell line enhanced hTCEpi: 35.3;SCLC-21H: 36.3 +DTX1 hDx-1 ENSG00000135144 Deltex E3 ubiquitin ligase 1 12 113056709-113098028 Enzymes, Predicted intracellular proteins Evidence at protein level HPA051249, HPA055275 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:3.02e-5 (unfavourable) Expressed in all Tissue enhanced lymph node: 13.4 spleen: 11.4 Group enriched 9 Daudi: 77.9;REH: 41.0;U-698: 75.9 +TRAFD1 FLN29 ENSG00000135148 TRAF-type zinc finger domain containing 1 12 112125501-112153609 Predicted intracellular proteins Evidence at protein level HPA039254, HPA039266 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:9.26e-6 (unfavourable), Urothelial cancer:3.92e-5 (favourable), Liver cancer:4.87e-4 (unfavourable), Cervical cancer:5.73e-4 (favourable) Expressed in all Expressed in all testis: 53.7 Expressed in all +DMTF1 DMP1, DMTF, hDMP1, MRUL ENSG00000135164 Cyclin D binding myb like transcription factor 1 7 87152361-87196337 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023846 Supported Supported Nucleoplasm Renal cancer:4.39e-5 (unfavourable) Expressed in all Expressed in all testis: 84.1 Expressed in all +OCM2 ENSG00000135175 Oncomodulin 2 7 97984684-97991169 Predicted intracellular proteins No evidence HPA046422 Uncertain Not detected Not detected testis: 0.1 Not detected +TMEM243 C7orf23, MGC4175, MM-TRAG ENSG00000135185 Transmembrane protein 243 7 87196160-87220587 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014918 Uncertain Lung cancer:5.45e-4 (favourable), Melanoma:6.84e-4 (unfavourable), Urothelial cancer:9.13e-4 (favourable) Expressed in all Expressed in all thyroid gland: 103.9 Expressed in all +CCDC146 KIAA1505 ENSG00000135205 Coiled-coil domain containing 146 7 77122434-77329533 Predicted intracellular proteins Evidence at protein level HPA020082, HPA020105 Uncertain Approved Golgi apparatus
Vesicles Head and neck cancer:7.37e-4 (favourable) Expressed in all Tissue enhanced fallopian tube: 57.6;testis: 39.3 thyroid gland: 13.8 Mixed +TMEM60 C7orf35, DC32 ENSG00000135211 Transmembrane protein 60 7 77793728-77798580 Predicted membrane proteins, Transporters Evidence at transcript level HPA062625 Approved Breast cancer:3.09e-4 (favourable), Glioma:8.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 56.4 Expressed in all +CD36 FAT, GP3B, GP4, GPIV, SCARB3 ENSG00000135218 CD36 molecule 7 80369575-80679277 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA002018, CAB025866, HPA071026 Enhanced Enhanced Golgi apparatus Stomach cancer:4.47e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 1617.9 Cell line enhanced ASC diff: 218.9;HEL: 144.7 +UGT2A3 FLJ21934 ENSG00000135220 UDP glucuronosyltransferase family 2 member A3 4 68928463-68951791 Enzymes, Predicted membrane proteins Evidence at protein level HPA045108 Supported Renal cancer:6.07e-7 (favourable), Colorectal cancer:3.31e-4 (favourable) Tissue enriched Tissue enhanced duodenum: 82.1;gallbladder: 46.3;kidney: 46.8;small intestine: 85.9 rectum: 23.9 Cell line enriched 8 Hep G2: 13.5 +CSN2 CASB ENSG00000135222 Casein beta 4 69955256-69961007 Predicted secreted proteins Evidence at protein level HPA041036 Supported Tissue enriched Tissue enriched 348 breast: 347.6 salivary gland: 0.9 Not detected +UGT2B28 ENSG00000135226 UDP glucuronosyltransferase family 2 member B28 4 69280499-69295050 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA045108 Uncertain Tissue enriched Tissue enriched 12 breast: 267.2 gallbladder: 21.5 Group enriched 9 Daudi: 2.1;NB-4: 1.7 +PNPLA8 IPLA2-2, IPLA2G, iPLA2gamma ENSG00000135241 Patatin like phospholipase domain containing 8 7 108470422-108569666 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020083 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:1.86e-6 (favourable) Expressed in all Expressed in all adrenal gland: 63.1 Expressed in all +HILPDA C7orf68, FLJ21076, HIG-2, HIG2 ENSG00000135245 Hypoxia inducible lipid droplet associated 7 128455849-128458418 Predicted membrane proteins Evidence at protein level HPA010515 Approved Supported Nucleoplasm
Lipid droplets Liver cancer:4.30e-11 (unfavourable), Renal cancer:2.05e-7 (unfavourable) Expressed in all Expressed in all esophagus: 107.8 Expressed in all +FAM71F1 FAM137A, NYD-SP18 ENSG00000135248 Family with sequence similarity 71 member F1 7 128709061-128731743 Predicted intracellular proteins Evidence at transcript level HPA020636 Uncertain Cytosol Tissue enriched Tissue enriched 145 testis: 82.6 epididymis: 0.5 Cell line enriched 16 NTERA-2: 16.3 +RINT1 FLJ11785, RINT-1 ENSG00000135249 RAD50 interactor 1 7 105532085-105567677 Predicted intracellular proteins Evidence at protein level HPA019875, HPA031646 Approved Approved Golgi apparatus Thyroid cancer:2.39e-5 (unfavourable) Expressed in all Expressed in all testis: 19.0 Expressed in all +SRPK2 SFRSK2 ENSG00000135250 SRSF protein kinase 2 7 105110704-105399308 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015522, HPA020876 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all testis: 197.4 Expressed in all +KCP CRIM2, FLJ33365, NET67 ENSG00000135253 Kielin/chordin-like protein 7 128862451-128910719 Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced kidney: 2.7;seminal vesicle: 3.3 gallbladder: 1.5 Cell line enhanced CAPAN-2: 8.4;HMC-1: 4.7;U-87 MG: 2.3 +TES DKFZP586B2022, TESS-2, TESTIN ENSG00000135269 Testin LIM domain protein 7 116210493-116258783 Predicted intracellular proteins Evidence at protein level HPA015269, HPA018123 Approved Supported Plasma membrane
Cell Junctions
Focal adhesion sites
Cytosol Pancreatic cancer:1.20e-5 (unfavourable), Renal cancer:8.71e-5 (favourable) Expressed in all Expressed in all seminal vesicle: 271.7 Cell line enhanced EFO-21: 215.5 +MDFIC HIC ENSG00000135272 MyoD family inhibitor domain containing 7 114922154-115019202 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA030716 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:3.65e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 48.0 Cell line enhanced U-2197: 101.4 +MTO1 ENSG00000135297 Mitochondrial tRNA translation optimization 1 6 73461578-73509236 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030230, HPA030232 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 24.9 Expressed in all +ADGRB3 BAI3, KIAA0550 ENSG00000135298 Adhesion G protein-coupled receptor B3 6 68635367-69389511 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 10 cerebral cortex: 53.1 adrenal gland: 5.1 Group enriched 5 SCLC-21H: 10.4;SH-SY5Y: 20.2 +ANKRD6 KIAA0957 ENSG00000135299 Ankyrin repeat domain 6 6 89433170-89633834 Predicted intracellular proteins Evidence at protein level CAB020693, HPA035694, HPA064642 Enhanced Supported Vesicles Mixed Mixed cerebral cortex: 23.7 Cell line enhanced AF22: 15.3;BEWO: 45.7;HAP1: 14.8 +HTR1B 5-HT1B, 5-HT1DB, HTR1D2, S12 ENSG00000135312 5-hydroxytryptamine receptor 1B 6 77461753-77463773 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA028808 Enhanced Uncertain Plasma membrane Mixed Tissue enhanced placenta: 10.0;stomach: 4.7 cerebral cortex: 2.4 Group enriched 16 HUVEC TERT2: 68.8;TIME: 29.9 +KHDC1 bA257K9.4, C6orf147, C6orf148, Em:AC019205.8, MGC10818, NDG1 ENSG00000135314 KH homology domain containing 1 6 73241314-73310365 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA029032 Approved Mitochondria
Cytosol Mixed Tissue enhanced cerebral cortex: 9.9 testis: 6.8 Mixed +CEP162 C6orf84, KIAA1009, QN1 ENSG00000135315 Centrosomal protein 162 6 84124241-84227635 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030170, HPA030171, HPA030172, HPA030173 Supported Enhanced Plasma membrane
Cytosol Expressed in all Mixed testis: 15.7 Mixed +SYNCRIP dJ3J17.2, GRY-RBP, hnRNP-Q, HNRNPQ, HNRPQ1, NSAP1 ENSG00000135316 Synaptotagmin binding cytoplasmic RNA interacting protein 6 85607785-85643792 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010895, HPA041275 Enhanced Enhanced Nucleoplasm
Cytosol Liver cancer:6.28e-5 (unfavourable), Ovarian cancer:5.59e-4 (favourable) Expressed in all Expressed in all thyroid gland: 132.3 Expressed in all +SNX14 RGS-PX2 ENSG00000135317 Sorting nexin 14 6 85505496-85594156 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017639 Approved Supported Cytosol Head and neck cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all testis: 156.6 Expressed in all +NT5E CALJA, CD73, eN, eNT, NT5 ENSG00000135318 5'-nucleotidase ecto 6 85449584-85495791 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017357 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:1.32e-5 (unfavourable), Stomach cancer:1.02e-4 (unfavourable), Lung cancer:6.66e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 172.7 smooth muscle: 106.3 Cell line enhanced LHCN-M2: 772.3;U-87 MG: 800.0 +MRAP2 bA51G5.2, C6orf117 ENSG00000135324 Melanocortin 2 receptor accessory protein 2 6 84033756-84090881 Disease related genes, Predicted membrane proteins Evidence at protein level Endometrial cancer:1.66e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 21.0 fallopian tube: 13.4 Group enriched 5 K-562: 81.0;SCLC-21H: 35.1 +EPHA7 Hek11 ENSG00000135333 EPH receptor A7 6 93240020-93419547 Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB010496 Approved Tissue enhanced Tissue enriched 13 parathyroid gland: 253.5 prostate: 20.2 Cell line enhanced AF22: 15.6;HEK 293: 41.9;RH-30: 41.8;THP-1: 25.7 +AKIRIN2 C6orf166, dJ486L4.2, FLJ10342 ENSG00000135334 Akirin 2 6 87675072-87702209 Predicted intracellular proteins Evidence at protein level HPA064239 Supported Nucleoplasm Expressed in all Expressed in all spleen: 58.2 Expressed in all +ORC3 IMAGE50150, LATHEO, ORC3L ENSG00000135336 Origin recognition complex subunit 3 6 87590067-87667453 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039553, HPA053748 Enhanced Enhanced Nucleoplasm Endometrial cancer:2.89e-5 (unfavourable), Renal cancer:7.23e-4 (unfavourable) Expressed in all Expressed in all testis: 48.9 Expressed in all +LCA5 C6orf152 ENSG00000135338 LCA5, lebercilin 6 79484991-79537458 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029053, HPA029055 Supported Renal cancer:4.69e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 48.1 fallopian tube: 15.6 Cell line enhanced HEL: 13.2 +MAP3K7 MEKK7, TAK1 ENSG00000135341 Mitogen-activated protein kinase kinase kinase 7 6 90513573-90587045 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007633 Approved Approved Nuclear speckles
Cytosol Liver cancer:3.51e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.0 Expressed in all +CGA FSHA, GPHa, GPHA1, HCG, LHA, TSHA ENSG00000135346 Glycoprotein hormones, alpha polypeptide 6 87085498-87095406 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB023350, HPA029698 Enhanced Tissue enhanced Tissue enriched 22 placenta: 654.5 stomach: 29.1 Cell line enriched 26 BEWO: 481.2 +GJA10 CX62 ENSG00000135355 Gap junction protein alpha 10 6 89894469-89921760 Predicted membrane proteins Evidence at protein level HPA021145 Uncertain Tissue enriched Not detected testis: 0.4 Not detected +PRR5L FLJ14213, PROTOR-2 ENSG00000135362 Proline rich 5 like 11 36296288-36465204 Predicted intracellular proteins Evidence at protein level HPA070174 Approved Cytokinetic bridge
Cytosol Renal cancer:7.71e-8 (unfavourable), Endometrial cancer:7.30e-5 (favourable), Stomach cancer:4.86e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 51.1 colon: 35.0 Cell line enhanced HMC-1: 51.8;hTERT-HME1: 46.7;SiHa: 43.9 +LMO2 RBTN2, RBTNL1, RHOM2, TTG2 ENSG00000135363 LIM domain only 2 11 33858576-33892289 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016258, HPA029285 Approved Approved Nucleoplasm
Cytosol Liver cancer:3.12e-4 (favourable) Expressed in all Mixed spleen: 25.7 Cell line enhanced HEL: 48.0;HL-60: 42.9;K-562: 49.4;THP-1: 47.5 +PHF21A BHC80, BM-006, KIAA1696 ENSG00000135365 PHD finger protein 21A 11 45929323-46121178 Predicted intracellular proteins Evidence at protein level HPA023580 Uncertain Renal cancer:2.59e-8 (unfavourable), Liver cancer:1.66e-6 (unfavourable), Colorectal cancer:6.15e-4 (unfavourable) Expressed in all Expressed in all testis: 43.7 Expressed in all +NAT10 FLJ10774, FLJ12179, hALP, KIAA1709, NET43 ENSG00000135372 N-acetyltransferase 10 11 34105602-34147670 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB035546, HPA057576, HPA071628 Enhanced Enhanced Nucleoli
Midbody Liver cancer:9.61e-8 (unfavourable), Renal cancer:8.83e-5 (unfavourable), Head and neck cancer:1.07e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.7 Expressed in all +EHF ESE3, ESEJ ENSG00000135373 ETS homologous factor 11 34621093-34661057 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA050923, HPA060734 Enhanced Supported Nucleoplasm
Golgi apparatus Colorectal cancer:5.81e-4 (favourable), Pancreatic cancer:6.94e-4 (unfavourable) Mixed Mixed esophagus: 228.3 Cell line enhanced CAPAN-2: 122.7;HaCaT: 85.2;HBEC3-KT: 76.2;RT4: 172.3;T-47d: 201.8 +ELF5 ENSG00000135374 E74 like ETS transcription factor 5 11 34478793-34513805 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062706 Supported Nucleoplasm Lung cancer:3.64e-4 (favourable) Tissue enhanced Tissue enhanced breast: 172.6;salivary gland: 64.2 seminal vesicle: 42.2 Group enriched 10 RT4: 24.0;T-47d: 53.3 +PRRG4 TMG4 ENSG00000135378 Proline rich and Gla domain 4 11 32829943-32858123 Predicted membrane proteins Evidence at protein level HPA009040, HPA024566 Uncertain Approved Golgi apparatus Expressed in all Mixed skin: 25.1 Cell line enhanced HaCaT: 47.2;hTCEpi: 20.5 +CAPRIN1 caprin-1, GPIAP1, M11S1, RNG105 ENSG00000135387 Cell cycle associated protein 1 11 34051683-34101156 Predicted intracellular proteins Evidence at protein level HPA018126, HPA063617 Approved Liver cancer:8.67e-8 (unfavourable) Expressed in all Expressed in all testis: 248.9 Expressed in all +ATP5G2 ENSG00000135390 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9) 12 53632726-53677408 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA051469 Approved Expressed in all Expressed in all fallopian tube: 779.5 Expressed in all +DNAJC14 DNAJ, DRIP78, FLJ32792, HDJ3, LIP6 ENSG00000135392 DnaJ heat shock protein family (Hsp40) member C14 12 55820960-55830824 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017653 Approved Expressed in all Expressed in all parathyroid gland: 49.4 Expressed in all +CD63 ME491, MLA1, TSPAN30 ENSG00000135404 CD63 molecule 12 55725323-55729707 CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA010088, CAB026356 Supported Supported Vesicles Liver cancer:1.37e-4 (unfavourable) Expressed in all Expressed in all epididymis: 1743.5 Expressed in all +PRPH NEF4, PRPH1 ENSG00000135406 Peripherin 12 49293252-49298686 Predicted intracellular proteins Evidence at protein level CAB002437, HPA039277, HPA063887 Enhanced Mixed Tissue enhanced adrenal gland: 20.5 testis: 11.6 Group enriched 93 AN3-CA: 342.0;SCLC-21H: 92.7 +AVIL ADVIL, DOC6, FLJ12386, p92 ENSG00000135407 Advillin 12 57797376-57818704 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058864 Approved Urothelial cancer:2.71e-4 (favourable) Expressed in all Mixed skin: 6.7 Cell line enhanced RH-30: 8.3 +AMHR2 MISR2, MISRII ENSG00000135409 Anti-Mullerian hormone receptor type 2 12 53423855-53431534 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced adrenal gland: 32.1;ovary: 40.9 testis: 10.1 Group enriched 19 HEL: 36.1;K-562: 19.9 +LACRT LACRITIN ENSG00000135413 Lacritin 12 54630811-54634895 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 6 salivary gland: 4.6 breast: 0.7 Not detected +GDF11 BMP-11 ENSG00000135414 Growth differentiation factor 11 12 55743280-55757278 Predicted secreted proteins Evidence at protein level HPA060985, HPA069609 Enhanced Approved Vesicles Pancreatic cancer:1.08e-4 (favourable) Expressed in all Mixed cerebral cortex,seminal vesicle: 13.3 Cell line enhanced HMC-1: 112.3 +GLS2 GA, GLS, hLGA, LGA ENSG00000135423 Glutaminase 2 12 56470944-56488414 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038608 Uncertain Tissue enhanced Tissue enriched 11 liver: 80.4 cerebral cortex: 7.2 Cell line enhanced Daudi: 22.6;SCLC-21H: 10.1 +ITGA7 ENSG00000135424 Integrin subunit alpha 7 12 55684568-55716043 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008427 Uncertain Approved Plasma membrane
Cytosol Urothelial cancer:9.59e-5 (unfavourable), Pancreatic cancer:1.75e-4 (favourable) Expressed in all Tissue enhanced adipose tissue: 154.7 smooth muscle: 136.8 Cell line enhanced ASC diff: 46.9;hTEC/SVTERT24-B: 66.1;SK-MEL-30: 38.6;U-87 MG: 57.9 +TESPA1 KIAA0748 ENSG00000135426 Thymocyte expressed, positive selection associated 1 12 54948018-54984746 Predicted intracellular proteins Evidence at protein level HPA058823 Approved Mixed Tissue enhanced lymph node: 46.7 cerebral cortex: 34.7 Group enriched 6 HEL: 238.5;HMC-1: 184.2 +FAM186B C12orf25, DKFZP434J0113 ENSG00000135436 Family with sequence similarity 186 member B 12 49582885-49605639 Predicted intracellular proteins Evidence at protein level HPA039736, HPA040028 Uncertain Not detected Tissue enriched 32 testis: 76.1 parathyroid gland: 2.3 Mixed +RDH5 HSD17B9, RDH1, SDR9C5 ENSG00000135437 Retinol dehydrogenase 5 12 55720367-55724705 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA063345 Approved Vesicles Mixed Tissue enhanced adipose tissue: 97.7 liver: 30.0 Cell line enhanced ASC diff: 19.5;ASC TERT1: 17.1;hTEC/SVTERT24-B: 15.2;LHCN-M2: 12.8;U-87 MG: 26.2 +AGAP2 CENTG1 ENSG00000135439 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 12 57723761-57742157 Predicted intracellular proteins Evidence at protein level HPA023474 Approved Supported Nucleus
Nucleoli
Mitochondria Tissue enriched Tissue enriched 7 cerebral cortex: 144.5 lymph node: 19.8 Cell line enhanced RH-30: 95.5 +BLOC1S1 BLOS1, BORCS1, GCN5L1 ENSG00000135441 Biogenesis of lysosomal organelles complex 1 subunit 1 12 55716037-55720087 Predicted intracellular proteins Evidence at protein level HPA021381 Approved Ovarian cancer:2.19e-4 (favourable), Cervical cancer:2.77e-4 (favourable) Expressed in all Expressed in all fallopian tube: 214.5 Expressed in all +KRT85 Hb-5, KRTHB5 ENSG00000135443 Keratin 85 12 52360006-52367481 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049778 Supported Not detected Not detected testis: 0.8 Cell line enhanced A549: 2.0 +CDK4 PSK-J3 ENSG00000135446 Cyclin dependent kinase 4 12 57747727-57756013 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006024, CAB013116, CAB069405 Enhanced Supported Nucleus
Nuclear membrane
Nucleoli
Cytosol Liver cancer:2.09e-7 (unfavourable), Renal cancer:3.15e-5 (unfavourable) Expressed in all Expressed in all endometrium: 121.7 Group enriched 9 HBEC3-KT: 1874.1;LHCN-M2: 2370.6;RH-30: 8554.0 +PPP1R1A ENSG00000135447 Protein phosphatase 1 regulatory inhibitor subunit 1A 12 54575387-54588659 Predicted intracellular proteins Evidence at protein level CAB007811, HPA041542 Approved Endometrial cancer:2.36e-5 (unfavourable) Tissue enhanced Tissue enhanced adipose tissue: 252.9;skeletal muscle: 291.2 kidney: 74.4 Cell line enhanced ASC diff: 6.1;NTERA-2: 29.5;RPTEC TERT1: 24.5 +TROAP TASTIN ENSG00000135451 Trophinin associated protein 12 49323236-49331731 Predicted intracellular proteins Evidence at protein level HPA044102 Uncertain Liver cancer:1.39e-5 (unfavourable) Mixed Tissue enhanced bone marrow: 32.0;testis: 44.1 tonsil: 13.7 Expressed in all +TSPAN31 SAS ENSG00000135452 Tetraspanin 31 12 57738013-57750211 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA057489 Approved Renal cancer:9.91e-5 (favourable), Head and neck cancer:1.09e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 74.5 Expressed in all +B4GALNT1 beta1-4GalNAc-T, GALGT, SPG26 ENSG00000135454 Beta-1,4-N-acetyl-galactosaminyltransferase 1 12 57623410-57633355 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008968, HPA015128 Enhanced Renal cancer:3.18e-14 (unfavourable) Tissue enriched Tissue enriched 6 cerebral cortex: 26.2 seminal vesicle: 4.0 Cell line enhanced EFO-21: 33.8;HDLM-2: 29.7 +TFCP2 CP2, LBP-1C, LSF, TFCP2C ENSG00000135457 Transcription factor CP2 12 51093663-51173134 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA070247 Supported Nucleoplasm
Cytosol Melanoma:1.18e-4 (unfavourable), Liver cancer:1.83e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 44.3 Mixed +COQ10A FLJ32452 ENSG00000135469 Coenzyme Q10A 12 56266858-56270966 Predicted intracellular proteins Evidence at protein level HPA068931 Approved Endoplasmic reticulum
Golgi apparatus
Cytosol Pancreatic cancer:2.06e-4 (favourable), Renal cancer:3.44e-4 (favourable), Colorectal cancer:5.46e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 97.2 Expressed in all +FAIM2 KIAA0950, LFG, LFG2, LIFEGUARD, NMP35, TMBIM2 ENSG00000135472 Fas apoptotic inhibitory molecule 2 12 49866896-49904217 Predicted membrane proteins Evidence at protein level HPA018790, HPA048800 Enhanced Approved Intermediate filaments Tissue enriched Tissue enriched 7 cerebral cortex: 369.7 adrenal gland: 55.7 Cell line enhanced HHSteC: 10.2;U-87 MG: 37.7 +PAN2 hPAN2, KIAA0710, USP52 ENSG00000135473 PAN2 poly(A) specific ribonuclease subunit 12 56316223-56334053 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:2.77e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.0 Expressed in all +ESPL1 ESP1, KIAA0165, SEPA ENSG00000135476 Extra spindle pole bodies like 1, separase 12 53268299-53293643 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB012185 Uncertain Supported Nucleoplasm
Vesicles Liver cancer:2.01e-5 (unfavourable), Endometrial cancer:5.32e-5 (unfavourable), Stomach cancer:7.10e-4 (favourable), Lung cancer:7.14e-4 (unfavourable) Mixed Tissue enhanced esophagus: 11.4;testis: 10.6 lymph node: 4.8 Mixed +KRT7 CK7, K2C7, K7, SCL ENSG00000135480 Keratin 7 12 52232520-52252186 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000028, HPA007272 Enhanced Renal cancer:2.77e-9 (favourable), Pancreatic cancer:7.78e-5 (unfavourable), Ovarian cancer:9.42e-5 (unfavourable), Endometrial cancer:1.99e-4 (unfavourable) Tissue enhanced Tissue enhanced thyroid gland: 984.0 urinary bladder: 454.0 Cell line enhanced HBEC3-KT: 4461.4;RT4: 5973.0;SiHa: 6200.7 +ZC3H10 FLJ14451, ZC3HDC10 ENSG00000135482 Zinc finger CCCH-type containing 10 12 56118159-56127514 Predicted intracellular proteins Evidence at protein level HPA039236, HPA062265 Uncertain Approved Vesicles Expressed in all Mixed testis: 10.3 Expressed in all +HNRNPA1 ALS20, hnRNP-A1, hnRNPA1, HNRPA1 ENSG00000135486 Heterogeneous nuclear ribonucleoprotein A1 12 54280193-54287088 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001609, HPA001666, HPA005812, HPA007185, CAB010894 Supported Enhanced Nucleoplasm Expressed in all Expressed in all ovary: 1919.7 Expressed in all +SLC26A10 ENSG00000135502 Solute carrier family 26 member 10 12 57619527-57626151 Predicted membrane proteins, Transporters Evidence at transcript level HPA044719 Uncertain Tissue enhanced Mixed endometrium: 1.7 Cell line enhanced NTERA-2: 3.0;RH-30: 2.2;SH-SY5Y: 4.4;U-266/70: 2.2 +ACVR1B ActRIB, ACVRLK4, ALK4, SKR2 ENSG00000135503 Activin A receptor type 1B 12 51951667-51997078 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB026126, HPA063761 Approved Enhanced Cytosol Expressed in all Expressed in all parathyroid gland: 54.6 Expressed in all +OS9 ERLEC2, OS-9 ENSG00000135506 OS9, endoplasmic reticulum lectin 12 57693955-57721557 Predicted secreted proteins, Transporters Evidence at protein level CAB011518, HPA013694 Supported Supported Endoplasmic reticulum Expressed in all Expressed in all parathyroid gland: 295.8 Cell line enriched 11 RH-30: 3430.4 +MIP AQP0, LIM1, MP26 ENSG00000135517 Major intrinsic protein of lens fiber 12 56449502-56469166 Disease related genes, Predicted membrane proteins Evidence at protein level HPA014940 Supported Not detected Tissue enhanced testis: 1.2 cerebral cortex,liver: 0.2 Not detected +KCNH3 BEC1, elk2, Kv12.2 ENSG00000135519 Potassium voltage-gated channel subfamily H member 3 12 49539157-49558308 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA051088 Uncertain Approved Nucleus
Mitochondria Tissue enhanced Group enriched 5 cerebral cortex: 24.2;fallopian tube: 7.1;parathyroid gland: 4.9 adrenal gland: 2.2 Cell line enhanced A549: 7.6;RPTEC TERT1: 7.7;U-2 OS: 11.2 +LTV1 C6orf93, dJ468K18.4, FLJ14909 ENSG00000135521 LTV1 ribosome biogenesis factor 6 143843344-143863812 Predicted intracellular proteins Evidence at protein level HPA030159, HPA030160, HPA030161 Approved Enhanced Nucleoplasm
Cytosol Renal cancer:6.01e-13 (unfavourable), Liver cancer:4.95e-5 (unfavourable) Expressed in all Expressed in all testis: 38.4 Expressed in all +MAP7 E-MAP-115 ENSG00000135525 Microtubule associated protein 7 6 136342281-136550819 Predicted intracellular proteins Evidence at protein level HPA029712, HPA029713 Enhanced Supported Microtubules
Cytosol Renal cancer:5.07e-7 (favourable), Cervical cancer:9.70e-5 (unfavourable), Liver cancer:9.22e-4 (favourable) Expressed in all Mixed cerebral cortex: 52.9 Cell line enhanced MCF7: 67.4 +CD164 DFNA66, MGC-24, MUC-24 ENSG00000135535 CD164 molecule 6 109366514-109382457 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010636 Uncertain Expressed in all Expressed in all thyroid gland: 613.1 Expressed in all +LACE1 AFG1 ENSG00000135537 Lactation elevated 1 6 108294894-108526796 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030154, HPA030155, HPA030659 Approved Approved Plasma membrane
Cytosol Mixed Tissue enhanced testis: 17.3 parathyroid gland: 8.5 Mixed +NHSL1 bA43P8.1, C6orf63, KIAA1357 ENSG00000135540 NHS like 1 6 138422043-138692571 Predicted intracellular proteins Evidence at protein level HPA029966, HPA029967, HPA029968 Uncertain Approved Nucleoplasm
Nuclear membrane Expressed in all Mixed small intestine: 25.8 Cell line enhanced TIME: 52.4 +AHI1 FLJ20069, JBTS3, ORF1 ENSG00000135541 Abelson helper integration site 1 6 135283532-135497776 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031698, HPA046684 Approved Approved Centrosome Renal cancer:4.07e-9 (unfavourable), Pancreatic cancer:7.51e-5 (favourable) Expressed in all Mixed testis: 51.3 Mixed +HEY2 bHLHb32, HERP1, HESR2 ENSG00000135547 Hes related family bHLH transcription factor with YRPW motif 2 6 125747664-125761269 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030205, HPA074851 Approved Approved Nuclear bodies
Aggresome Expressed in all Mixed fallopian tube: 21.6 Cell line enhanced HEK 293: 6.3;SK-MEL-30: 5.0;TIME: 11.9;U-266/70: 13.2 +PKIB PRKACN2 ENSG00000135549 CAMP-dependent protein kinase inhibitor beta 6 122471917-122726373 Predicted intracellular proteins Evidence at protein level HPA030156 Approved Renal cancer:2.47e-7 (favourable), Liver cancer:4.72e-7 (unfavourable) Expressed in all Tissue enhanced colon: 89.1;placenta: 85.4 parathyroid gland: 78.0 Cell line enhanced AF22: 71.0;PC-3: 106.9;RPTEC TERT1: 141.0;SCLC-21H: 186.3 +TAAR5 PNR ENSG00000135569 Trace amine associated receptor 5 6 132588673-132589686 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA051703 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +NMBR BB1, BB1R ENSG00000135577 Neuromedin B receptor 6 142058330-142088799 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA026665 Supported Plasma membrane
Cytosol Not detected Group enriched 5 fallopian tube: 1.4;testis: 2.6 cerebral cortex: 0.3 Not detected +SMPD2 ISC1, nSMase ENSG00000135587 Sphingomyelin phosphodiesterase 2 6 109440763-109443919 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018110, HPA018125 Uncertain Approved Vesicles
Plasma membrane
Cell Junctions Liver cancer:1.17e-4 (unfavourable), Urothelial cancer:1.70e-4 (favourable), Pancreatic cancer:1.00e-3 (favourable) Expressed in all Mixed testis: 55.8 Expressed in all +MICAL1 DKFZp434B1517, FLJ11937, FLJ21739, MICAL, NICAL ENSG00000135596 Microtubule associated monooxygenase, calponin and LIM domain containing 1 6 109444062-109465968 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030175, HPA030176, HPA030178 Approved Pancreatic cancer:2.63e-7 (favourable), Renal cancer:6.71e-7 (unfavourable) Expressed in all Mixed bone marrow: 39.5 Cell line enhanced THP-1: 95.6 +REPS1 ENSG00000135597 RALBP1 associated Eps domain containing 1 6 138903493-138988261 Predicted intracellular proteins Evidence at protein level HPA029961, HPA029962 Approved Approved Vesicles
Plasma membrane
Cytosol Liver cancer:9.47e-4 (unfavourable) Expressed in all Expressed in all testis: 66.1 Expressed in all +STX11 ENSG00000135604 Syntaxin 11 6 144150526-144188370 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA007992, HPA076253 Approved Supported Nuclear bodies
Mitochondria Expressed in all Tissue enhanced bone marrow: 100.8 adipose tissue: 32.1 Cell line enhanced HDLM-2: 37.8;Karpas-707: 15.3;TIME: 14.2;U-266/70: 19.0 +TEC PSCTK4 ENSG00000135605 Tec protein tyrosine kinase 4 48135783-48269864 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005733, HPA024657 Approved Supported Plasma membrane Ovarian cancer:7.12e-4 (favourable) Mixed Mixed epididymis: 5.0 Cell line enhanced HEL: 11.8;HMC-1: 17.4;U-266/70: 15.1;U-266/84: 10.6 +PRADC1 C2orf7, hPAP21, MGC13004, PAP21 ENSG00000135617 Protease associated domain containing 1 2 73228006-73233238 Predicted secreted proteins Evidence at protein level HPA051066 Approved Expressed in all Expressed in all heart muscle: 46.8 Expressed in all +SEMA4F SEMAM, SEMAW ENSG00000135622 Ssemaphorin 4F 2 74654228-74683853 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA064095, HPA065969 Approved Approved Nucleus
Plasma membrane
Centrosome Renal cancer:9.74e-6 (unfavourable), Endometrial cancer:5.94e-5 (unfavourable), Glioma:3.18e-4 (unfavourable), Thyroid cancer:6.94e-4 (favourable) Expressed in all Mixed cerebral cortex: 14.1 Mixed +CCT7 Ccth, Nip7-1 ENSG00000135624 Chaperonin containing TCP1 subunit 7 2 73233420-73253021 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008425 Approved Approved Cytosol Liver cancer:1.84e-5 (unfavourable), Endometrial cancer:2.69e-4 (unfavourable) Expressed in all Expressed in all testis: 286.8 Expressed in all +EGR4 NGFI-C, PAT133 ENSG00000135625 Early growth response 4 2 73290929-73293705 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028983 Enhanced Mixed Group enriched 29 cerebral cortex: 9.7;testis: 3.2 adipose tissue,appendix: 0.2 Cell line enriched 6 HMC-1: 1.4 +RAB11FIP5 GAF1, KIAA0857, pp75, RIP11 ENSG00000135631 RAB11 family interacting protein 5 2 73073382-73156721 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036406, HPA036407 Enhanced Enhanced Vesicles
Microtubule organizing center Renal cancer:2.26e-5 (favourable), Ovarian cancer:3.87e-4 (unfavourable) Expressed in all Tissue enhanced testis: 73.1 parathyroid gland: 26.9 Mixed +SMYD5 NN8-4AG, RAI15, RRG1, ZMYND23 ENSG00000135632 SMYD family member 5 2 73214222-73227237 Predicted intracellular proteins Evidence at protein level HPA015514, HPA049002 Uncertain Approved Mitochondria Liver cancer:6.58e-7 (unfavourable) Expressed in all Expressed in all ovary: 34.2 Expressed in all +DYSF FER1L1, LGMD2B ENSG00000135636 Dysferlin 2 71453722-71686768 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB002510, HPA017071, HPA021945 Enhanced Supported Plasma membrane
Microtubule organizing center Expressed in all Mixed skeletal muscle: 32.8 Group enriched 6 HUVEC TERT2: 69.0;LHCN-M2: 62.5;RH-30: 75.9;TIME: 44.6 +CCDC142 FLJ14397 ENSG00000135637 Coiled-coil domain containing 142 2 74471986-74483408 Predicted intracellular proteins Evidence at transcript level HPA056946 Approved Renal cancer:3.71e-7 (unfavourable), Endometrial cancer:1.87e-4 (unfavourable), Liver cancer:4.46e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 5.8 Mixed +EMX1 ENSG00000135638 Empty spiracles homeobox 1 2 72916260-72936071 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006230, HPA006421 Approved Approved Nucleoli Renal cancer:1.54e-6 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 8.3;kidney: 15.5;parathyroid gland: 5.0 testis: 2.6 Cell line enhanced BEWO: 2.2;CACO-2: 3.1;HEK 293: 7.5 +KCNMB4 ENSG00000135643 Potassium calcium-activated channel subfamily M regulatory beta subunit 4 12 70366276-70434292 Predicted membrane proteins Evidence at protein level HPA072287 Enhanced Approved Cytosol Mixed Group enriched 8 adrenal gland: 19.5;cerebral cortex: 38.1 placenta: 3.7 Cell line enhanced NTERA-2: 7.7;RH-30: 8.0;RT4: 7.4 +USP15 KIAA0529, UNPH4 ENSG00000135655 Ubiquitin specific peptidase 15 12 62260338-62417431 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006237, HPA006428, HPA071014 Approved Enhanced Cytosol Renal cancer:1.58e-5 (unfavourable), Liver cancer:8.04e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 121.6 Expressed in all +GNS ENSG00000135677 Glucosamine (N-acetyl)-6-sulfatase 12 64713445-64759447 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA013695, CAB026011, HPA048508 Enhanced Liver cancer:1.94e-5 (unfavourable), Glioma:4.17e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 172.9 Expressed in all +CPM ENSG00000135678 Carboxypeptidase M 12 68842197-68971570 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA002657, HPA077243 Uncertain Uncertain Vesicles Endometrial cancer:1.00e-4 (favourable) Expressed in all Tissue enhanced adipose tissue: 164.0 placenta: 101.2 Cell line enhanced ASC diff: 48.8;ASC TERT1: 35.1;HSkMC: 66.3;SiHa: 73.7 +MDM2 HDM2, MGC5370 ENSG00000135679 MDM2 proto-oncogene 12 68808176-68850686 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB000086, CAB016303 Supported Supported Nucleus Endometrial cancer:4.51e-7 (favourable), Cervical cancer:3.23e-4 (favourable) Expressed in all Expressed in all rectum: 33.9 Expressed in all +KLHL36 C16orf44, FLJ12543 ENSG00000135686 Kelch like family member 36 16 84648525-84667686 Predicted intracellular proteins Evidence at protein level HPA023423 Approved Approved Cytosol Renal cancer:5.52e-10 (favourable), Pancreatic cancer:9.81e-5 (favourable) Expressed in all Expressed in all testis: 20.1 Mixed +BCO1 BCDO, BCDO1, BCMO, BCMO1, FLJ10730 ENSG00000135697 Beta-carotene oxygenase 1 16 81238448-81291142 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043811 Uncertain Actin filaments
Microtubule organizing center Mixed Tissue enhanced duodenum: 8.7;small intestine: 14.8 kidney: 3.3 Cell line enhanced A549: 9.9;EFO-21: 7.6;HAP1: 3.2;NTERA-2: 4.4;RPTEC TERT1: 6.2 +MPHOSPH6 MPP6 ENSG00000135698 M-phase phosphoprotein 6 16 82147798-82170226 Predicted intracellular proteins Evidence at protein level CAB003674, HPA026948 Approved Supported Nucleus
Nucleoli Ovarian cancer:3.41e-5 (favourable), Liver cancer:4.36e-5 (unfavourable), Prostate cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all breast: 91.8 Expressed in all +CHST5 FLJ22167, I-GLCNAC-6-ST ENSG00000135702 Carbohydrate sulfotransferase 5 16 75528535-75535247 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA043804 Enhanced Group enriched Group enriched 14 colon: 45.6;duodenum: 85.9;rectum: 59.7;small intestine: 83.5 stomach: 4.8 Mixed +KIAA0513 ENSG00000135709 KIAA0513 16 85027751-85094230 Predicted intracellular proteins Evidence at protein level HPA012866, HPA014431 Enhanced Uncertain Nucleoplasm
Cytosol Pancreatic cancer:1.72e-5 (favourable) Expressed in all Tissue enriched 7 cerebral cortex: 102.6 adrenal gland: 14.9 Mixed +DYNC1LI2 DNCLI2 ENSG00000135720 Dynein cytoplasmic 1 light intermediate chain 2 16 66720893-66751798 Predicted intracellular proteins Evidence at protein level HPA057201 Approved Centrosome
Cytosol Expressed in all Expressed in all parathyroid gland: 141.9 Expressed in all +FBXL8 Fbl8 ENSG00000135722 F-box and leucine rich repeat protein 8 16 67159931-67164570 Predicted intracellular proteins Evidence at protein level HPA035587, HPA035588 Uncertain Approved Golgi apparatus Endometrial cancer:5.39e-4 (favourable) Expressed in all Expressed in all prostate: 29.2 Mixed +FHOD1 FHOS ENSG00000135723 Formin homology 2 domain containing 1 16 67229387-67247658 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024468 Approved Supported Cytosol Renal cancer:1.90e-8 (unfavourable), Cervical cancer:9.57e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 62.3 skeletal muscle: 40.4 Expressed in all +CCDC102A MGC10992 ENSG00000135736 Coiled-coil domain containing 102A 16 57512178-57536599 Predicted intracellular proteins Evidence at protein level HPA040598, HPA040958 Supported Approved Nucleoplasm
Nuclear bodies Expressed in all Mixed prostate: 5.5 Mixed +SLC9A5 NHE5 ENSG00000135740 Solute carrier family 9 member A5 16 67237683-67272190 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041004, HPA041329 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced spleen: 7.8 cerebral cortex: 2.5 Cell line enhanced U-138 MG: 5.9 +AGT SERPINA8 ENSG00000135744 Angiotensinogen 1 230702523-230714297 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001557, CAB025798 Supported Group enriched Tissue enhanced cerebral cortex: 226.5;liver: 649.6 gallbladder: 133.7 Cell line enhanced CACO-2: 60.4;Hep G2: 401.1;THP-1: 150.6 +PCNX2 FLJ11383, KIAA0435, PCNXL2 ENSG00000135749 Pecanex homolog 2 (Drosophila) 1 232983435-233295713 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013815, HPA014427 Uncertain Approved Endoplasmic reticulum Renal cancer:2.27e-5 (unfavourable) Mixed Mixed cerebral cortex: 14.0 Mixed +KCNK1 DPK, K2p1.1, TWIK-1 ENSG00000135750 Potassium two pore domain channel subfamily K member 1 1 233614004-233672512 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA016049, CAB022588 Approved Approved Vesicles Renal cancer:8.69e-8 (unfavourable), Liver cancer:3.84e-4 (favourable), Pancreatic cancer:7.29e-4 (unfavourable) Mixed Mixed cerebral cortex: 46.4 Cell line enhanced SCLC-21H: 70.2;U-266/70: 104.5;U-266/84: 92.8 +URB2 KIAA0133, NET10, NPA2 ENSG00000135763 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 1 229626234-229660199 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008902, HPA046788 Uncertain Enhanced Nucleoli Expressed in all Mixed testis: 10.6 Expressed in all +EGLN1 C1orf12, HIFPH2, PHD2, SM-20, ZMYND6 ENSG00000135766 Egl-9 family hypoxia inducible factor 1 1 231363751-231425044 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA022129 Approved Approved Cytosol Cervical cancer:2.99e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.9 Expressed in all +CAPN9 GC36, nCL-4 ENSG00000135773 Calpain 9 1 230747384-230802003 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020398, CAB033483 Enhanced Mixed Tissue enhanced rectum: 25.2;stomach: 58.9 colon: 14.4 Cell line enriched 9 SCLC-21H: 17.8 +COG2 LDLC ENSG00000135775 Component of oligomeric golgi complex 2 1 230642489-230693982 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA076994 Approved Golgi apparatus Colorectal cancer:9.76e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 77.2 Expressed in all +ABCB10 EST20237, M-ABC2, MTABC2 ENSG00000135776 ATP binding cassette subfamily B member 10 1 229516582-229558695 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB044063, CAB044065, HPA055175 Uncertain Expressed in all Expressed in all bone marrow: 36.5 Expressed in all +NTPCR C1orf57, HCR-NTPase, MGC13186 ENSG00000135778 Nucleoside-triphosphatase, cancer-related 1 232950605-232983882 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028125, HPA054304 Uncertain Approved Cytosol Expressed in all Mixed parathyroid gland: 11.4 Mixed +TAF5L PAF65B ENSG00000135801 TATA-box binding protein associated factor 5 like 1 229593111-229626047 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA067941 Enhanced Nuclear speckles
Cytoplasmic bodies Expressed in all Expressed in all placenta: 20.6 Expressed in all +GLUL GLNS ENSG00000135821 Glutamate-ammonia ligase 1 182381704-182392206 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007316, HPA007571, CAB008636 Approved Supported Mitochondria
Cytosol Breast cancer:4.81e-4 (favourable) Expressed in all Expressed in all adipose tissue: 851.0 Cell line enhanced ASC diff: 791.8;ASC TERT1: 567.1;HSkMC: 512.4 +STX6 ENSG00000135823 Syntaxin 6 1 180972712-181023121 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA038557, HPA038558 Approved Enhanced Nucleoplasm
Golgi apparatus Renal cancer:1.93e-8 (unfavourable), Liver cancer:6.24e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 30.2 Expressed in all +RGS8 MGC119067, MGC119068, MGC119069 ENSG00000135824 Regulator of G-protein signaling 8 1 182641816-182684576 Predicted intracellular proteins Evidence at protein level HPA076764 Supported Group enriched Group enriched 5 cerebral cortex: 5.3;testis: 4.9;thyroid gland: 11.3 adrenal gland: 1.3 Group enriched 5 AF22: 5.6;SCLC-21H: 18.7 +RNASEL PRCA1, RNS4 ENSG00000135828 Ribonuclease L 1 182573634-182589256 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002633, CAB010906 Approved Supported Cytosol Expressed in all Mixed parathyroid gland: 17.6 Mixed +DHX9 DDX9, LKP, RHA ENSG00000135829 DExH-box helicase 9 1 182839369-182887751 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011819, HPA028050, HPA055684 Supported Enhanced Nucleus Liver cancer:3.17e-4 (unfavourable), Melanoma:6.04e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 137.9 Expressed in all +KIAA1614 ENSG00000135835 KIAA1614 1 180913154-180951614 Predicted intracellular proteins Evidence at protein level HPA028227, HPA061684 Approved Approved Nuclear membrane
Vesicles Mixed Mixed thyroid gland: 9.2 Cell line enhanced RH-30: 17.2;SH-SY5Y: 47.3 +CEP350 CAP350, KIAA0480 ENSG00000135837 Centrosomal protein 350 1 179954738-180114880 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028355, HPA028357, HPA030845 Enhanced Supported Centrosome Renal cancer:1.02e-4 (unfavourable) Expressed in all Expressed in all testis: 44.7 Expressed in all +NPL C1orf13, DHDPS1, NPL1 ENSG00000135838 N-acetylneuraminate pyruvate lyase 1 182789293-182830384 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028345 Approved Vesicles
Plasma membrane Renal cancer:6.63e-4 (unfavourable), Liver cancer:8.05e-4 (unfavourable) Expressed in all Mixed placenta: 63.8 Mixed +FAM129A C1orf24, GIG39, NIBAN ENSG00000135842 Family with sequence similarity 129 member A 1 184790724-184974550 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA028172, HPA028231, HPA028657 Approved Supported Plasma membrane
Cytosol Urothelial cancer:4.52e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 104.1 Mixed +PIGC ENSG00000135845 Phosphatidylinositol glycan anchor biosynthesis class C 1 172370189-172444086 Enzymes, Predicted membrane proteins Evidence at protein level HPA036663 Uncertain Renal cancer:1.43e-8 (unfavourable), Liver cancer:4.49e-4 (unfavourable) Expressed in all Expressed in all epididymis: 47.7 Expressed in all +LAMC1 LAMB2 ENSG00000135862 Laminin subunit gamma 1 1 183023460-183145592 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001908, HPA001909, CAB004486, CAB078163 Enhanced Approved Endoplasmic reticulum
Plasma membrane Urothelial cancer:8.85e-5 (unfavourable) Expressed in all Tissue enhanced placenta: 332.9 smooth muscle: 147.5 Cell line enhanced ASC diff: 1091.5;HSkMC: 716.3 +RC3H1 KIAA2025, RNF198, roquin, RP5-1198E17.5 ENSG00000135870 Ring finger and CCCH-type domains 1 1 173931214-174022297 Predicted intracellular proteins Evidence at protein level HPA027428, HPA027434, HPA027448 Approved Supported Plasma membrane
Cytosol Renal cancer:7.96e-4 (unfavourable) Expressed in all Mixed bone marrow: 12.9 Mixed +GPR55 ENSG00000135898 G protein-coupled receptor 55 2 230907318-230961066 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced spleen: 5.8;testis: 9.0 tonsil: 4.4 Cell line enhanced HDLM-2: 6.0;Karpas-707: 23.3;SK-MEL-30: 4.7 +SP110 IFI41, IFI75 ENSG00000135899 SP110 nuclear body protein 2 230167293-230225729 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047036, HPA058554 Approved Supported Nucleus Renal cancer:1.17e-5 (unfavourable) Expressed in all Expressed in all spleen: 66.3 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 94.0 +MRPL44 FLJ12701, FLJ13990 ENSG00000135900 Mitochondrial ribosomal protein L44 2 223957404-223967714 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA038147, HPA038148 Approved Approved Nucleus
Plasma membrane
Mitochondria Liver cancer:1.29e-4 (unfavourable), Renal cancer:2.02e-4 (favourable) Expressed in all Expressed in all kidney: 37.5 Expressed in all +CHRND ACHRD ENSG00000135902 Cholinergic receptor nicotinic delta subunit 2 232525993-232536667 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA056404, HPA065404 Supported Nucleoplasm
Plasma membrane
Cytosol Tissue enriched Tissue enriched 12 skeletal muscle: 9.6 prostate: 0.8 Cell line enriched 76 RH-30: 79.9 +PAX3 HUP2, WS1 ENSG00000135903 Paired box 3 2 222199888-222298996 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063659, HPA069000 Approved Supported Nucleoplasm Tissue enriched Group enriched 8 breast: 1.2;skeletal muscle: 1.1;skin: 3.2;testis: 2.4 prostate: 0.2 Cell line enhanced BJ hTERT+ SV40 Large T+: 9.6;BJ hTERT+ SV40 Large T+ RasG12V: 11.6;RH-30: 16.2;SK-MEL-30: 24.6 +DOCK10 KIAA0694, ZIZ3 ENSG00000135905 Dedicator of cytokinesis 10 2 224765090-225042445 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058106 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Mixed spleen: 46.6 Cell line enhanced HDLM-2: 50.8 +TTLL4 KIAA0173 ENSG00000135912 Tubulin tyrosine ligase like 4 2 218710845-218755416 Predicted intracellular proteins Evidence at protein level HPA027091, HPA050252 Approved Approved Mitochondria Renal cancer:6.63e-12 (unfavourable), Liver cancer:2.95e-5 (unfavourable) Expressed in all Expressed in all testis: 46.8 Expressed in all +USP37 KIAA1594 ENSG00000135913 Ubiquitin specific peptidase 37 2 218450251-218568361 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045160 Approved Approved Nucleus
Nucleoli Head and neck cancer:2.85e-4 (favourable) Mixed Mixed testis: 23.2 Expressed in all +HTR2B 5-HT(2B), 5-HT2B ENSG00000135914 5-hydroxytryptamine receptor 2B 2 231108230-231125118 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA012867, HPA063658 Enhanced Approved Nucleoplasm Mixed Tissue enhanced cervix, uterine: 31.2;endometrium: 30.1;smooth muscle: 23.2 adrenal gland: 19.1 Cell line enhanced HHSteC: 7.0;HSkMC: 11.5;SK-MEL-30: 23.9 +ITM2C BRI3, BRICD2C, E25, hRPC.1050_D_4, ITM3 ENSG00000135916 Integral membrane protein 2C 2 230864639-230879248 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Endometrial cancer:1.81e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 852.3 Mixed +SLC19A3 THTR2 ENSG00000135917 Solute carrier family 19 member 3 2 227685210-227718012 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA038898 Approved Approved Nucleoplasm
Cytosol Mixed Tissue enhanced adipose tissue: 50.2;placenta: 35.3 duodenum: 12.3 Cell line enhanced ASC diff: 6.9;BEWO: 6.1;CACO-2: 12.7 +SERPINE2 GDN, nexin, PI7, PN1, PNI ENSG00000135919 Serpin family E member 2 2 223975112-224039319 Plasma proteins, Predicted secreted proteins Evidence at protein level Urothelial cancer:6.48e-5 (unfavourable) Tissue enriched Tissue enriched 7 placenta: 1628.0 cerebral cortex: 235.8 Cell line enhanced fHDF/TERT166: 5130.1;SK-MEL-30: 2298.5;WM-115: 2211.8 +DNAJB2 CMT2T, HSJ1, HSPF3 ENSG00000135924 DnaJ heat shock protein family (Hsp40) member B2 2 219279267-219286900 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036268 Approved Enhanced Nuclear membrane Colorectal cancer:1.01e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 161.8 Expressed in all +WNT10A ENSG00000135925 Wnt family member 10A 2 218880363-218899581 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013898 Uncertain Tissue enhanced Tissue enhanced skin: 8.3 placenta: 3.9 Cell line enhanced CAPAN-2: 36.8;HaCaT: 106.8;HDLM-2: 47.5;U-266/70: 47.5 +TMBIM1 LFG3, PP1201, RECS1 ENSG00000135926 Transmembrane BAX inhibitor motif containing 1 2 218274192-218292586 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012093, HPA070824 Approved Supported Vesicles Renal cancer:3.38e-4 (favourable), Pancreatic cancer:4.22e-4 (unfavourable) Expressed in all Expressed in all esophagus: 269.0 Expressed in all +CYP27A1 CP27, CTX, CYP27 ENSG00000135929 Cytochrome P450 family 27 subfamily A member 1 2 218781749-218815293 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA059155 Enhanced Enhanced Mitochondria Liver cancer:8.62e-6 (favourable), Breast cancer:1.05e-4 (favourable) Expressed in all Tissue enhanced liver: 279.5 lung: 98.4 Cell line enhanced Hep G2: 187.0;RPTEC TERT1: 50.8;SK-MEL-30: 86.7;WM-115: 42.3 +EIF4E2 4EHP, EIF4EL3, IF4e ENSG00000135930 Eukaryotic translation initiation factor 4E family member 2 2 232550052-232583644 Predicted intracellular proteins Evidence at protein level HPA019253 Approved Mitochondria
Cytosol Liver cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all rectum: 75.2 Expressed in all +ARMC9 ARM, FLJ12584, KIAA1868, KU-MEL-1 ENSG00000135931 Armadillo repeat containing 9 2 231198546-231374837 Predicted intracellular proteins Evidence at protein level HPA019041, HPA026671 Approved Approved Nucleoli
Cytosol Urothelial cancer:7.66e-5 (unfavourable) Mixed Mixed smooth muscle: 34.0 Cell line enhanced BJ hTERT+: 223.1;SK-MEL-30: 176.9 +CAB39 CGI-66, MO25 ENSG00000135932 Calcium binding protein 39 2 230712845-230821075 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037112 Supported Approved Nucleoli fibrillar center
Cytosol Renal cancer:9.05e-6 (favourable), Pancreatic cancer:8.33e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 78.9 Expressed in all +COX5B ENSG00000135940 Cytochrome c oxidase subunit 5B 2 97646040-97648383 Predicted intracellular proteins, Transporters Evidence at protein level HPA034517 Supported Enhanced Mitochondria Urothelial cancer:2.73e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 447.7 Expressed in all +REV1 REV1L ENSG00000135945 REV1, DNA directed polymerase 2 99400475-99490035 Predicted intracellular proteins Evidence at protein level HPA044534, HPA051036 Uncertain Approved Cytosol Prostate cancer:2.03e-4 (unfavourable) Expressed in all Expressed in all endometrium: 23.2 Expressed in all +TSGA10 CEP4L, CT79 ENSG00000135951 Testis specific 10 2 98997261-99154964 Predicted intracellular proteins Evidence at protein level HPA036879 Approved Cytosol Mixed Group enriched 11 fallopian tube: 19.2;testis: 92.9 thyroid gland: 4.8 Cell line enhanced RPTEC TERT1: 3.1 +MFSD9 MGC11332 ENSG00000135953 Major facilitator superfamily domain containing 9 2 102715840-102736888 Predicted membrane proteins Evidence at protein level HPA055293, HPA061859 Approved Approved Nucleoli Glioma:7.48e-4 (unfavourable) Expressed in all Mixed duodenum: 9.8 Expressed in all +TMEM127 FLJ20507, FLJ22257 ENSG00000135956 Transmembrane protein 127 2 96248516-96265994 Cancer-related genes, Disease related genes, Predicted membrane proteins Evidence at protein level Renal cancer:6.69e-5 (favourable), Liver cancer:6.59e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 112.5 Expressed in all +EDAR DL, ED1R, ED3, ED5, EDA1R, EDA3, Edar ENSG00000135960 Ectodysplasin A receptor 2 108894471-108989372 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA042292 Approved Mixed Mixed esophagus: 2.8 Group enriched 7 CAPAN-2: 4.0;HaCaT: 8.7 +TGFBRAP1 TRAP-1, TRAP1, VPS3 ENSG00000135966 Transforming growth factor beta receptor associated protein 1 2 105264391-105330034 Predicted intracellular proteins Evidence at protein level HPA037672, HPA038397 Approved Approved Vesicles Expressed in all Expressed in all parathyroid gland: 20.9 Expressed in all +GCC2 GCC185, KIAA0336 ENSG00000135968 GRIP and coiled-coil domain containing 2 2 108448561-108509415 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035849, HPA035850 Enhanced Enhanced Nucleoplasm
Golgi apparatus Liver cancer:4.24e-4 (unfavourable) Expressed in all Mixed epididymis: 34.0 Expressed in all +MRPS9 MRP-S9, RPMS9, S9mt ENSG00000135972 Mitochondrial ribosomal protein S9 2 105037983-105099960 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043476, HPA048479 Enhanced Enhanced Nucleoli
Mitochondria Liver cancer:4.43e-4 (unfavourable) Expressed in all Expressed in all testis: 57.4 Expressed in all +GPR45 PSP24, PSP24A ENSG00000135973 G protein-coupled receptor 45 2 105241743-105243049 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA055940 Uncertain Not detected Tissue enhanced cerebral cortex: 1.8 testis: 0.4 Group enriched 14 BEWO: 1.3;U-2 OS: 4.5 +C2orf49 asw, MGC5509 ENSG00000135974 Chromosome 2 open reading frame 49 2 105337359-105349211 Predicted intracellular proteins Evidence at protein level HPA043846, HPA060814 Approved Supported Nucleoplasm
Mitochondria Renal cancer:5.06e-5 (unfavourable) Expressed in all Expressed in all ovary: 24.2 Expressed in all +ANKRD36 UNQ2430 ENSG00000135976 Ankyrin repeat domain 36 2 97113496-97264521 Predicted intracellular proteins Evidence at protein level HPA051757, HPA057661 Approved Nucleus
Cytosol Mixed Mixed testis: 13.4 Mixed +EPC2 DKFZP566F2124 ENSG00000135999 Enhancer of polycomb homolog 2 2 148644440-148787568 Predicted intracellular proteins Evidence at protein level HPA036759 Uncertain Approved Nuclear speckles Expressed in all Expressed in all endometrium: 44.3 Expressed in all +ARHGEF4 ASEF, KIAA1112, STM6 ENSG00000136002 Rho guanine nucleotide exchange factor 4 2 130836916-131047263 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018267 Approved Testis cancer:7.00e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 61.6;skin: 44.1 esophagus: 14.5 Cell line enhanced HaCaT: 31.5;hTCEpi: 52.8;SCLC-21H: 52.6 +ISCU hnifU, IscU, ISU2, NIFUN ENSG00000136003 Iron-sulfur cluster assembly enzyme 12 108562582-108569384 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB006329, HPA038602, HPA057592 Approved Supported Cytosol Renal cancer:2.73e-7 (favourable), Cervical cancer:4.90e-7 (favourable), Urothelial cancer:6.12e-4 (favourable) Expressed in all Expressed in all adrenal gland: 399.3 Expressed in all +ALDH1L2 FLJ38508, mtFDH ENSG00000136010 Aldehyde dehydrogenase 1 family member L2 12 105019784-105084577 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039481, HPA059282 Uncertain Enhanced Mitochondria Mixed Mixed cervix, uterine: 8.4 Cell line enhanced ASC TERT1: 58.5;fHDF/TERT166: 77.9 +STAB2 DKFZP434E0321, FEEL-2, FELL, HARE, SCARH1, STAB-2 ENSG00000136011 Stabilin 2 12 103587273-103766727 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026871 Enhanced Uncertain Cytosol Not detected Tissue enriched 6 spleen: 48.3 liver: 7.8 Cell line enhanced BEWO: 11.1;HaCaT: 2.8 +USP44 FLJ14528 ENSG00000136014 Ubiquitin specific peptidase 44 12 95516560-95551490 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026543 Approved Nucleoli fibrillar center
Microtubules Tissue enhanced Tissue enriched 7 testis: 43.6 parathyroid gland: 6.0 Cell line enriched 6 NTERA-2: 137.8 +SCYL2 CVAK104, KIAA1360 ENSG00000136021 SCY1 like pseudokinase 2 12 100267140-100341724 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021050 Approved Expressed in all Expressed in all parathyroid gland: 41.8 Expressed in all +CKAP4 CLIMP-63, ERGIC-63, P63 ENSG00000136026 Cytoskeleton associated protein 4 12 106237877-106304279 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000278, HPA000792, HPA001225 Enhanced Uncertain Nuclear speckles
Cytosol
Cytoplasmic bodies Renal cancer:0.00e+0 (unfavourable), Liver cancer:6.61e-5 (unfavourable), Lung cancer:5.61e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 78.5 Cell line enhanced BJ hTERT+: 563.9;fHDF/TERT166: 652.4 +PLXNC1 CD232, VESPR ENSG00000136040 Plexin C1 12 94148723-94307675 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB026155, HPA066899 Uncertain Approved Mitochondria Expressed in all Mixed testis: 28.5 Cell line enhanced HAP1: 34.3;SK-MEL-30: 32.7;U-266/70: 49.2;U-266/84: 50.5 +APPL2 DIP13B, FLJ10659 ENSG00000136044 Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 12 105173296-105236238 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039688, HPA043925 Approved Renal cancer:7.65e-4 (favourable) Expressed in all Expressed in all skin: 78.0 Expressed in all +PWP1 IEF-SSP-9502 ENSG00000136045 PWP1 homolog, endonuclein 12 107685732-107713167 Predicted intracellular proteins Evidence at protein level HPA038708 Approved Nucleoli
Golgi apparatus Liver cancer:1.40e-5 (unfavourable), Renal cancer:2.26e-4 (unfavourable), Head and neck cancer:9.65e-4 (unfavourable) Expressed in all Expressed in all testis: 55.0 Expressed in all +DRAM1 DRAM, FLJ11259 ENSG00000136048 DNA damage regulated autophagy modulator 1 12 101877351-102012130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Endometrial cancer:6.52e-8 (favourable), Renal cancer:3.91e-4 (unfavourable) Expressed in all Expressed in all lung: 130.5 Cell line enhanced BJ hTERT+: 400.1 +WASHC4 KIAA1033, SWIP ENSG00000136051 WASH complex subunit 4 12 105107324-105169134 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045666, HPA046737 Uncertain Enhanced Nucleoplasm Cervical cancer:2.02e-4 (unfavourable) Expressed in all Expressed in all lymph node: 51.1 Expressed in all +SLC41A2 DKFZP434K0427 ENSG00000136052 Solute carrier family 41 member 2 12 104802553-104958744 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA038658 Approved Renal cancer:3.35e-4 (unfavourable), Liver cancer:9.94e-4 (favourable) Expressed in all Mixed liver: 60.0 Cell line enhanced HDLM-2: 52.1 +VILL ENSG00000136059 Villin like 3 37988059-38007188 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035675 Enhanced Glioma:1.16e-4 (unfavourable), Head and neck cancer:1.75e-4 (favourable) Tissue enhanced Tissue enhanced stomach: 93.8 small intestine: 67.6 Cell line enhanced CAPAN-2: 21.9 +FLNB ABP-278, FH1, FLN1L, LRS1, TABP, TAP ENSG00000136068 Filamin B 3 58008400-58172251 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA004747, HPA004886, CAB019322 Enhanced Supported Golgi apparatus
Plasma membrane
Actin filaments
Cytosol Renal cancer:3.45e-6 (favourable), Pancreatic cancer:8.45e-5 (unfavourable) Expressed in all Expressed in all prostate: 148.3 Expressed in all +NEK3 HSPK36, MGC29949 ENSG00000136098 NIMA related kinase 3 13 52132639-52159861 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019062, HPA043230 Enhanced Approved Microtubules Expressed in all Expressed in all testis: 29.6 Mixed +PCDH8 ARCADLIN, PAPC ENSG00000136099 Protocadherin 8 13 52842889-52848641 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA010509 Uncertain Uncertain Golgi apparatus
Cytosol Tissue enhanced Tissue enriched 8 cerebral cortex: 5.7 testis: 0.7 Group enriched 7 AF22: 23.5;NTERA-2: 4.9;SCLC-21H: 6.4 +VPS36 C13orf9, CGI-145, Eap45 ENSG00000136100 Vacuolar protein sorting 36 homolog 13 52412602-52450628 Predicted intracellular proteins Evidence at protein level HPA039734, HPA043947 Approved Supported Vesicles
Lysosomes
Plasma membrane
Cell Junctions Renal cancer:9.91e-6 (favourable) Expressed in all Expressed in all skin: 62.4 Expressed in all +RNASEH2B AGS2, DLEU8, FLJ11712 ENSG00000136104 Ribonuclease H2 subunit B 13 50909678-50973745 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040084, HPA041469 Approved Enhanced Nucleus Renal cancer:2.54e-8 (unfavourable) Expressed in all Expressed in all thyroid gland: 29.9 Expressed in all +CKAP2 FLJ10749, LB1, se20-10, TMAP ENSG00000136108 Cytoskeleton associated protein 2 13 52455429-52476628 Predicted intracellular proteins Evidence at protein level HPA008410, HPA027821 Enhanced Enhanced Microtubules
Cytosol Renal cancer:1.90e-5 (unfavourable), Liver cancer:3.26e-5 (unfavourable) Expressed in all Tissue enhanced testis: 58.5 bone marrow: 42.4 Expressed in all +CNMD BRICD3, CHM-I, CHM1, LECT1, MYETS1 ENSG00000136110 Chondromodulin 13 52703264-52739812 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010510 Uncertain Group enriched Tissue enhanced salivary gland: 3.0;testis: 3.5;thyroid gland: 5.8 lung: 2.5 Cell line enriched 125 NTERA-2: 47.4 +TBC1D4 AS160, DKFZp779C0666, KIAA0603 ENSG00000136111 TBC1 domain family member 4 13 75284665-75482114 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA040145, HPA059885 Approved Supported Cytosol Renal cancer:1.07e-11 (favourable) Expressed in all Expressed in all adrenal gland: 82.8 Cell line enhanced CACO-2: 70.0 +THSD1 TMTSP ENSG00000136114 Thrombospondin type 1 domain containing 1 13 52377167-52406494 Predicted membrane proteins Evidence at protein level HPA012611, CAB020796 Uncertain Enhanced Cytosol Expressed in all Mixed lung: 16.6 Cell line enhanced HUVEC TERT2: 34.0 +BORA C13orf34, FLJ22624 ENSG00000136122 Bora, aurora kinase A activator 13 72727749-72756198 Predicted intracellular proteins Evidence at protein level HPA040866 Approved Approved Nucleus
Nucleoli Expressed in all Mixed lymph node: 10.4 Expressed in all +LRCH1 CHDC1, KIAA1016 ENSG00000136141 Leucine rich repeats and calponin homology domain containing 1 13 46553168-46753040 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021536 Uncertain Approved Nucleoli
Actin filaments
Cytosol Renal cancer:1.04e-4 (favourable), Ovarian cancer:5.75e-4 (unfavourable), Cervical cancer:6.24e-4 (unfavourable), Lung cancer:6.67e-4 (unfavourable) Expressed in all Expressed in all endometrium: 26.8 Expressed in all +SUCLA2 ENSG00000136143 Succinate-CoA ligase ADP-forming beta subunit 13 47936491-48001354 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039435, HPA039536, HPA061528 Enhanced Supported Enhanced Mitochondria Renal cancer:7.59e-14 (favourable), Urothelial cancer:1.22e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 78.7 Expressed in all +RCBTB1 CLLD7, CLLL7, FLJ10716 ENSG00000136144 RCC1 and BTB domain containing protein 1 13 49531946-49585583 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056783 Approved Nucleoplasm Ovarian cancer:1.21e-5 (unfavourable), Lung cancer:5.51e-5 (favourable), Renal cancer:1.75e-4 (favourable) Expressed in all Expressed in all thyroid gland: 74.0 Expressed in all +MED4 DRIP36, HSPC126, TRAP36, VDRIP ENSG00000136146 Mediator complex subunit 4 13 48053323-48095131 Predicted intracellular proteins Evidence at protein level HPA006232 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 103.5 Expressed in all +PHF11 BCAP, IGER, NY-REN-34 ENSG00000136147 PHD finger protein 11 13 49495610-49528987 Predicted intracellular proteins Evidence at protein level HPA016566, HPA016708 Uncertain Supported Nucleoplasm
Nuclear membrane Renal cancer:4.46e-7 (unfavourable), Endometrial cancer:7.98e-6 (favourable), Urothelial cancer:3.46e-4 (favourable) Expressed in all Expressed in all thyroid gland: 57.6 Mixed +COG3 SEC34 ENSG00000136152 Component of oligomeric golgi complex 3 13 45464898-45536630 Predicted secreted proteins Evidence at protein level HPA040353, HPA054470 Approved Supported Nucleoplasm
Golgi apparatus
Plasma membrane
Cytosol Ovarian cancer:9.53e-4 (unfavourable) Expressed in all Expressed in all prostate: 30.7 Expressed in all +LMO7 FBX20, FBXO20, KIAA0858 ENSG00000136153 LIM domain 7 13 75620434-75859870 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020923, HPA050184 Approved Supported Actin filaments
Cytosol Renal cancer:7.75e-12 (favourable), Pancreatic cancer:3.51e-4 (unfavourable), Endometrial cancer:5.12e-4 (unfavourable) Expressed in all Expressed in all lung: 269.4 Cell line enhanced fHDF/TERT166: 440.3;LHCN-M2: 438.5 +SCEL FLJ21667, MGC22531 ENSG00000136155 Sciellin 13 77535674-77645263 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039737, HPA040154 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:1.73e-5 (unfavourable), Pancreatic cancer:1.24e-4 (unfavourable), Endometrial cancer:4.07e-4 (unfavourable), Renal cancer:6.87e-4 (favourable) Mixed Tissue enhanced esophagus: 476.6;skin: 397.0 lung: 98.9 Cell line enhanced CAPAN-2: 28.9;HaCaT: 54.8;HBEC3-KT: 21.3;RPTEC TERT1: 89.6 +ITM2B BRI, BRI2, BRICD2B, E25B, E3-16 ENSG00000136156 Integral membrane protein 2B 13 48233158-48270357 Disease related genes, Predicted membrane proteins Evidence at protein level HPA029292, HPA071992 Approved Enhanced Golgi apparatus
Vesicles Renal cancer:3.73e-5 (favourable) Expressed in all Expressed in all epididymis: 1855.0 Expressed in all +SPRY2 hSPRY2 ENSG00000136158 Sprouty RTK signaling antagonist 2 13 80335976-80340951 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB037205, HPA042198 Approved Supported Microtubules Expressed in all Expressed in all adipose tissue: 69.7 Cell line enhanced AN3-CA: 269.3 +NUDT15 FLJ10956, MTH2 ENSG00000136159 Nudix hydrolase 15 13 48037567-48047222 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038968, HPA038969 Approved Supported Nucleoplasm Melanoma:1.25e-5 (unfavourable) Expressed in all Expressed in all prostate: 22.8 Expressed in all +EDNRB ETB, HSCR, HSCR2 ENSG00000136160 Endothelin receptor type B 13 77895481-77919768 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB017842, HPA027546 Approved Supported Plasma membrane
Cytosol Renal cancer:7.20e-5 (favourable) Group enriched Tissue enhanced placenta: 180.2 cerebral cortex: 88.8 Cell line enhanced AF22: 59.4;ASC diff: 35.4;SK-MEL-30: 42.0;U-266/70: 29.1;WM-115: 122.9 +RCBTB2 CHC1L ENSG00000136161 RCC1 and BTB domain containing protein 2 13 48488959-48533256 Predicted intracellular proteins Evidence at protein level HPA040242 Approved Approved Nucleus
Golgi apparatus Renal cancer:2.45e-4 (favourable) Expressed in all Expressed in all thyroid gland: 45.0 Cell line enriched 10 MOLT-4: 221.7 +LCP1 CP64, L-PLASTIN, LC64P, PLS2 ENSG00000136167 Lymphocyte cytosolic protein 1 13 46125920-46211871 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019493, CAB020673 Enhanced Approved Plasma membrane
Actin filaments
Cytosol Expressed in all Expressed in all lymph node: 614.4 Cell line enhanced HDLM-2: 728.6;HL-60: 666.2;HMC-1: 741.0;U-698: 751.3 +SETDB2 C13orf4, CLLD8, CLLL8, KMT1F ENSG00000136169 SET domain bifurcated 2 13 49444374-49495003 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012190, HPA071677 Approved Approved Nucleoplasm Renal cancer:1.92e-7 (favourable) Expressed in all Mixed testis: 28.2 Expressed in all +SCRN1 KIAA0193 ENSG00000136193 Secernin 1 7 29920103-29990289 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024517 Enhanced Approved Cytosol Renal cancer:1.15e-5 (favourable), Endometrial cancer:4.00e-5 (unfavourable), Urothelial cancer:2.60e-4 (unfavourable), Ovarian cancer:7.27e-4 (unfavourable), Breast cancer:8.32e-4 (unfavourable), Cervical cancer:8.46e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 172.0 parathyroid gland: 129.1 Mixed +C7orf25 MGC2821 ENSG00000136197 Chromosome 7 open reading frame 25 7 42908726-42912305 Predicted intracellular proteins Evidence at protein level HPA020120, HPA049635 Approved Supported Nucleoplasm
Cytosol Not detected Mixed testis: 7.9 Expressed in all +TNS3 FLJ13732, H_NH0549I23.2, TEM6, TENS1 ENSG00000136205 Tensin 3 7 47275154-47582558 Predicted intracellular proteins Evidence at protein level HPA055338, HPA056015 Approved Enhanced Focal adhesion sites Renal cancer:5.21e-4 (favourable) Expressed in all Expressed in all placenta: 81.5 Cell line enhanced A549: 240.1 +SPDYE1 Ringo1, SPDYE, WBSCR19 ENSG00000136206 Speedy/RINGO cell cycle regulator family member E1 7 44000889-44010122 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051750 Supported Mixed Tissue enriched 6 testis: 8.2 skin: 1.3 Mixed +CHST12 C4S-2, C4ST2 ENSG00000136213 Carbohydrate sulfotransferase 12 7 2403560-2448483 Enzymes, Predicted membrane proteins Evidence at protein level HPA041680 Approved Approved Golgi apparatus Pancreatic cancer:1.32e-5 (favourable) Expressed in all Expressed in all spleen: 16.1 Cell line enhanced U-266/70: 68.5 +IGF2BP3 CT98, IMP-3, IMP3 ENSG00000136231 Insulin like growth factor 2 mRNA binding protein 3 7 23310209-23470467 Predicted intracellular proteins Evidence at protein level HPA002037 Approved Enhanced Cytosol Mixed Tissue enhanced placenta: 41.6 testis: 9.3 Mixed +GPNMB HGFIN, NMB ENSG00000136235 Glycoprotein nmb 7 23235967-23275108 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Expressed in all Expressed in all skin: 654.6 Cell line enriched 5 ASC diff: 3230.9 +RAPGEF5 GFR, KIAA0277, MR-GEF ENSG00000136237 Rap guanine nucleotide exchange factor 5 7 22118238-22357144 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA057821, HPA076772 Uncertain Supported Nucleoplasm
Nuclear bodies Head and neck cancer:3.52e-5 (favourable), Endometrial cancer:9.44e-4 (unfavourable) Expressed in all Tissue enriched 12 parathyroid gland: 1205.9 placenta: 97.1 Cell line enhanced HUVEC TERT2: 37.6;SCLC-21H: 40.3;TIME: 21.0;U-698: 26.6 +RAC1 p21-Rac1, Rac-1, TC-25 ENSG00000136238 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 7 6374523-6403977 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB035994, HPA047820 Approved Approved Nucleus
Nucleoli
Cytosol Liver cancer:1.74e-5 (unfavourable), Pancreatic cancer:4.57e-5 (unfavourable), Renal cancer:2.11e-4 (unfavourable), Lung cancer:4.59e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 281.6 Expressed in all +KDELR2 ELP-1, ERD2.2 ENSG00000136240 KDEL endoplasmic reticulum protein retention receptor 2 7 6445953-6484242 Predicted membrane proteins Evidence at protein level HPA016459 Approved Renal cancer:6.79e-8 (unfavourable), Head and neck cancer:1.03e-5 (unfavourable), Glioma:8.16e-5 (unfavourable) Expressed in all Expressed in all placenta: 204.0 Expressed in all +NUPL2 CG1, H_RG271G13.9, hCG1, NLP_1 ENSG00000136243 Nucleoporin like 2 7 23181827-23201011 Predicted intracellular proteins, Transporters Evidence at protein level HPA049036, HPA057251 Enhanced Nucleus Expressed in all Expressed in all testis: 32.2 Expressed in all +IL6 BSF2, HGF, HSF, IFNB2, IL-6 ENSG00000136244 Interleukin 6 7 22725884-22732002 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB023406, CAB072821 Supported Approved Vesicles Renal cancer:1.10e-11 (unfavourable) Mixed Tissue enhanced adipose tissue: 136.4 urinary bladder: 73.6 Group enriched 7 BJ hTERT+: 1844.6;hTEC/SVTERT24-B: 429.5 +ZDHHC4 FLJ10479, ZNF374 ENSG00000136247 Zinc finger DHHC-type containing 4 7 6577434-6589374 Enzymes, Predicted membrane proteins Evidence at protein level HPA032124, HPA064358 Approved Approved Nuclear bodies Renal cancer:1.18e-7 (favourable), Head and neck cancer:3.95e-6 (unfavourable), Urothelial cancer:8.94e-4 (unfavourable), Cervical cancer:9.35e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 77.7 Mixed +AOAH ENSG00000136250 Acyloxyacyl hydrolase 7 36512949-36724549 Enzymes, Predicted secreted proteins Evidence at protein level HPA021666, HPA026716 Uncertain Expressed in all Tissue enhanced spleen: 88.9 appendix: 45.9 Group enriched 6 HDLM-2: 3.4;NB-4: 16.7;THP-1: 13.5;U-937: 6.8 +BZW2 HSPC028, MST017, MSTP017 ENSG00000136261 Basic leucine zipper and W2 domains 2 7 16646131-16706523 Predicted intracellular proteins Evidence at protein level HPA022813, HPA026709 Approved Approved Plasma membrane
Actin filaments
Cytosol Liver cancer:7.86e-8 (unfavourable), Renal cancer:6.01e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 173.5 Expressed in all +DGKB DAGK2, DGK, DGK-BETA, KIAA0718 ENSG00000136267 Diacylglycerol kinase beta 7 14145049-14974777 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020321 Supported Tissue enriched Tissue enriched 6 cerebral cortex: 34.2 endometrium: 5.6 Cell line enhanced AF22: 1.2;fHDF/TERT166: 2.0;SCLC-21H: 1.5;U-266/70: 2.5 +TBRG4 Cpr2, FASTKD4, H_TD2522F11.8, KIAA0948 ENSG00000136270 Transforming growth factor beta regulator 4 7 45100100-45112047 Predicted intracellular proteins Evidence at protein level HPA020582, HPA050430 Approved Enhanced Mitochondria Liver cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all testis: 41.8 Expressed in all +DDX56 NOH61 ENSG00000136271 DEAD-box helicase 56 7 44565417-44575051 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019749, CAB037320 Uncertain Renal cancer:8.41e-7 (unfavourable), Liver cancer:1.38e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland,skin: 5.6 Expressed in all +HUS1 ENSG00000136273 HUS1 checkpoint clamp component 7 47695730-47979581 Predicted intracellular proteins Evidence at protein level HPA026787 Approved Cervical cancer:4.25e-5 (unfavourable), Liver cancer:9.54e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 12.3 Expressed in all +NACAD KIAA0363 ENSG00000136274 NAC alpha domain containing 7 45080438-45088914 Predicted intracellular proteins Evidence at protein level HPA020981 Enhanced Approved Nucleus
Cytosol Glioma:2.23e-4 (unfavourable) Group enriched Tissue enriched 6 cerebral cortex: 48.7 ovary: 7.6 Cell line enhanced SCLC-21H: 30.5;SH-SY5Y: 19.0 +DBNL ABP1, HIP-55, SH3P7 ENSG00000136279 Drebrin like 7 44044640-44069456 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020265, HPA027735 Enhanced Supported Nucleoplasm
Cytosol Glioma:3.20e-5 (unfavourable) Expressed in all Expressed in all esophagus: 141.9 Expressed in all +CCM2 C7orf22, MGC4607, OSM ENSG00000136280 CCM2 scaffolding protein 7 44999475-45076469 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020273, HPA021669, HPA065815 Enhanced Enhanced Mitochondria Renal cancer:5.06e-7 (unfavourable), Pancreatic cancer:1.16e-4 (favourable), Colorectal cancer:1.79e-4 (unfavourable), Glioma:3.77e-4 (unfavourable) Expressed in all Expressed in all lymph node: 49.1 Expressed in all +MYO1G HA-2 ENSG00000136286 Myosin IG 7 44962662-44979098 Predicted intracellular proteins Evidence at protein level HPA021252 Enhanced Renal cancer:8.71e-8 (unfavourable), Cervical cancer:8.26e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 27.7;lymph node: 27.7;spleen: 24.6 appendix: 21.9 Cell line enhanced HDLM-2: 53.6;HEL: 62.4;HL-60: 31.8;MOLT-4: 71.7;THP-1: 52.2;U-937: 44.7 +TTYH3 KIAA1691 ENSG00000136295 Tweety family member 3 7 2631951-2664802 Predicted membrane proteins Evidence at protein level HPA053520 Uncertain Liver cancer:2.53e-5 (unfavourable), Renal cancer:2.58e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 62.2 Expressed in all +MMD2 PAQR10 ENSG00000136297 Monocyte to macrophage differentiation associated 2 7 4905989-4959213 Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Group enriched 83 cerebral cortex: 41.2;testis: 12.4 adrenal gland: 0.3 Not detected +CIDEB ENSG00000136305 Cell death-inducing DFFA-like effector b 14 24305096-24311430 Predicted intracellular proteins Evidence at protein level HPA001272 Uncertain Mixed Expressed in all liver: 184.0 Cell line enhanced HDLM-2: 39.8;Hep G2: 32.5;HL-60: 24.6;U-937: 28.0 +TTC5 Strap ENSG00000136319 Tetratricopeptide repeat domain 5 14 20256558-20305994 Predicted intracellular proteins Evidence at protein level HPA045008, HPA054198 Approved Supported Nucleoplasm Renal cancer:8.54e-4 (favourable) Expressed in all Mixed parathyroid gland: 10.5 Mixed +NKX2-8 Nkx2-9, NKX2.8, NKX2H ENSG00000136327 NK2 homeobox 8 14 36580579-36582607 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062879 Uncertain Approved Nucleoplasm
Plasma membrane Mixed Tissue enhanced testis: 3.1 lung: 0.6 Cell line enhanced HaCaT: 4.6;PC-3: 2.8;SiHa: 1.3 +NKX2-1 BCH, NKX2A, TITF1, TTF-1, TTF1 ENSG00000136352 NK2 homeobox 1 14 36516392-36521149 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000078, CAB053633, HPA074316 Enhanced Uncertain Golgi apparatus
Vesicles Group enriched Group enriched 177 lung: 101.3;thyroid gland: 103.5 stomach: 0.5 Cell line enriched 36 SCLC-21H: 119.8 +ZFHX2 KIAA1056, KIAA1762, ZFH-5, ZNF409 ENSG00000136367 Zinc finger homeobox 2 14 23520855-23556192 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000720, HPA005146 Uncertain Approved Nucleus
Nucleoli fibrillar center Mixed Tissue enhanced testis: 13.0 parathyroid gland: 4.0 Cell line enhanced AN3-CA: 4.5 +MTHFS HsT19268 ENSG00000136371 Methenyltetrahydrofolate synthetase 15 79833585-79897379 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008067, HPA054177 Approved Supported Cytosol Liver cancer:1.29e-6 (favourable), Renal cancer:2.04e-4 (favourable), Glioma:6.94e-4 (unfavourable) Expressed in all Expressed in all liver: 116.1 Expressed in all +ADAMTS7 ADAM-TS7, DKFZp434H204 ENSG00000136378 ADAM metallopeptidase with thrombospondin type 1 motif 7 15 78759203-78811431 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA045284, HPA048453 Uncertain Supported Vesicles Stomach cancer:9.53e-4 (unfavourable) Mixed Tissue enhanced endometrium: 7.2 heart muscle: 4.3 Cell line enriched 9 HMC-1: 229.5 +ABHD17C FAM108C1 ENSG00000136379 Abhydrolase domain containing 17C 15 80679684-80755621 Predicted intracellular proteins Evidence at protein level HPA048890 Uncertain Expressed in all Mixed colon: 64.0 Mixed +IREB2 IRP2 ENSG00000136381 Iron responsive element binding protein 2 15 78437431-78501456 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032885, HPA040371, HPA068982 Uncertain Approved Cell Junctions
Cytosol Expressed in all Expressed in all thyroid gland: 48.0 Expressed in all +ALPK3 KIAA1330, MAK, Midori ENSG00000136383 Alpha kinase 3 15 84816680-84873482 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026558 Uncertain Approved Nucleus Renal cancer:3.95e-7 (favourable) Mixed Tissue enhanced heart muscle: 32.8;parathyroid gland: 36.2;skeletal muscle: 47.6 adipose tissue: 12.3 Cell line enhanced BEWO: 12.8;HUVEC TERT2: 12.1;LHCN-M2: 16.5;NTERA-2: 12.1;RH-30: 34.1 +TM6SF1 ENSG00000136404 Transmembrane 6 superfamily member 1 15 83107407-83144854 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA016051, HPA056857 Uncertain Renal cancer:6.79e-4 (favourable) Mixed Mixed thyroid gland: 13.3 Cell line enhanced HEL: 16.0;HHSteC: 33.2;HUVEC TERT2: 18.1;TIME: 46.3 +CIB2 DFNB48, KIP2, USH1J ENSG00000136425 Calcium and integrin binding family member 2 15 78104606-78131544 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036697 Approved Supported Renal cancer:6.16e-4 (favourable), Endometrial cancer:7.05e-4 (unfavourable) Expressed in all Mixed testis: 31.4 Cell line enhanced AN3-CA: 39.7;HAP1: 43.8;SCLC-21H: 46.7;SH-SY5Y: 48.9 +CALCOCO2 MGC17318, NDP52 ENSG00000136436 Calcium binding and coiled-coil domain 2 17 48830988-48866522 Predicted intracellular proteins Evidence at protein level HPA022989, HPA023019, HPA023195 Enhanced Supported Vesicles
Cytosol Expressed in all Expressed in all testis: 249.4 Expressed in all +RSAD1 FLJ11164 ENSG00000136444 Radical S-adenosyl methionine domain containing 1 17 50478800-50485975 Predicted intracellular proteins Evidence at protein level HPA022436, HPA022967 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:5.04e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 36.7 Expressed in all +NMT1 NMT ENSG00000136448 N-myristoyltransferase 1 17 45051610-45109016 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022949, HPA022963 Enhanced Supported Plasma membrane
Cytosol Liver cancer:4.94e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 58.6 Expressed in all +MYCBPAP AMAP-1, DKFZp434N1415 ENSG00000136449 MYCBP associated protein 17 50508384-50531501 Predicted intracellular proteins Evidence at protein level HPA023257, HPA024405 Enhanced Approved Vesicles Mixed Tissue enriched 12 testis: 91.5 fallopian tube: 7.5 Cell line enhanced HDLM-2: 3.7 +SRSF1 ASF, MGC5228, SF2, SF2p33, SFRS1, SRp30a ENSG00000136450 Serine and arginine rich splicing factor 1 17 58003360-58007346 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013073, HPA061301 Supported Enhanced Nucleoplasm Liver cancer:1.64e-6 (unfavourable), Renal cancer:2.95e-5 (unfavourable), Colorectal cancer:4.56e-5 (favourable), Cervical cancer:7.00e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 156.5 Expressed in all +VEZF1 DB1, ZNF161 ENSG00000136451 Vascular endothelial zinc finger 1 17 57971547-57988259 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027520, HPA048315 Uncertain Enhanced Nucleoplasm Colorectal cancer:6.14e-5 (favourable), Liver cancer:6.46e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 82.1 Expressed in all +CHAD SLRR4A ENSG00000136457 Chondroadherin 17 50464496-50468966 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018241 Enhanced Liver cancer:1.59e-4 (favourable), Breast cancer:7.68e-4 (favourable) Tissue enhanced Tissue enhanced cervix, uterine: 31.8 adrenal gland: 13.4 Cell line enhanced RT4: 3.4;SCLC-21H: 10.1 +TACO1 CCDC44 ENSG00000136463 Translational activator of cytochrome c oxidase I 17 63600872-63608365 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021626, HPA021643, HPA024294 Enhanced Enhanced Mitochondria Pancreatic cancer:3.73e-4 (favourable) Expressed in all Expressed in all kidney: 30.7 Expressed in all +TEX2 HT008, KIAA1738, TMEM96 ENSG00000136478 Testis expressed 2 17 64147227-64263301 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020648, HPA057116 Approved Approved Nucleus Colorectal cancer:3.90e-6 (favourable) Expressed in all Expressed in all testis: 99.6 Expressed in all +DCAF7 HAN11, SWAN-1, WDR68 ENSG00000136485 DDB1 and CUL4 associated factor 7 17 63550461-63594266 Predicted intracellular proteins Evidence at protein level HPA022948, HPA022962 Enhanced Supported Nucleoplasm
Cytosol Liver cancer:2.42e-4 (unfavourable), Renal cancer:3.49e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 61.4 Expressed in all +GH2 GH-V, GHL, GHV, hGH-V ENSG00000136487 Growth hormone 2 17 63880215-63881935 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA043715 Supported Not detected Tissue enriched 199 placenta: 189.1 smooth muscle: 0.9 Cell line enriched 21 BEWO: 7.8 +CSH1 CSA, CSMT, FLJ75407, hCS-A, PL ENSG00000136488 Chorionic somatomammotropin hormone 1 17 63894909-63896661 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026374, HPA043715 Enhanced Tissue enriched Tissue enriched 211 placenta: 13487.0 smooth muscle: 63.9 Cell line enriched 6 BEWO: 11.1 +LIMD2 MGC10986 ENSG00000136490 LIM domain containing 2 17 63695902-63701172 Predicted intracellular proteins Evidence at protein level HPA062867 Approved Vesicles Renal cancer:5.36e-11 (unfavourable) Expressed in all Group enriched 5 appendix: 140.1;bone marrow: 71.2;lymph node: 255.5;spleen: 191.0;tonsil: 138.2 urinary bladder: 30.2 Cell line enhanced Daudi: 173.9;SH-SY5Y: 172.7;U-698: 174.0 +BRIP1 BACH1, FANCJ, OF ENSG00000136492 BRCA1 interacting protein C-terminal helicase 1 17 61681266-61863521 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005474 Approved Supported Nucleus
Nuclear membrane Colorectal cancer:3.45e-5 (favourable), Head and neck cancer:3.62e-4 (favourable) Mixed Tissue enhanced testis: 14.4 bone marrow: 5.0 Cell line enhanced MCF7: 77.7 +KAT7 HBO1, HBOA, MYST2, ZC2HC7 ENSG00000136504 Lysine acetyltransferase 7 17 49788555-49835030 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044470 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 107.0 Expressed in all +RTP4 IFRG28, Z3CXXC4 ENSG00000136514 Receptor transporter protein 4 3 187368332-187372076 Predicted membrane proteins Evidence at protein level HPA064887, HPA071189 Uncertain Supported Nucleus Urothelial cancer:1.45e-4 (favourable), Thyroid cancer:4.35e-4 (favourable), Pancreatic cancer:6.83e-4 (unfavourable) Expressed in all Mixed fallopian tube: 16.7 Cell line enhanced CAPAN-2: 9.2;HDLM-2: 11.0;SK-MEL-30: 14.0 +ACTL6A Actl6, Arp4, BAF53A, INO80K ENSG00000136518 Actin like 6A 3 179562880-179588408 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012188, HPA018671 Supported Enhanced Nucleoplasm
Cytosol Liver cancer:1.89e-5 (unfavourable), Renal cancer:4.80e-5 (unfavourable), Pancreatic cancer:5.44e-5 (unfavourable) Expressed in all Expressed in all testis: 112.6 Expressed in all +NDUFB5 CI-SGDH, MGC12314, SGDH ENSG00000136521 NADH:ubiquinone oxidoreductase subunit B5 3 179604690-179627647 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005640 Enhanced Supported Nucleoplasm
Mitochondria Renal cancer:3.32e-5 (favourable) Expressed in all Expressed in all heart muscle: 136.7 Expressed in all +MRPL47 CGI-204, NCM1 ENSG00000136522 Mitochondrial ribosomal protein L47 3 179588285-179604654 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA037553, HPA047779 Approved Enhanced Mitochondria Endometrial cancer:3.15e-4 (unfavourable), Cervical cancer:6.44e-4 (favourable) Expressed in all Expressed in all testis: 85.1 Expressed in all +TRA2B Htra2-beta, PPP1R156, SFRS10 ENSG00000136527 Transformer 2 beta homolog (Drosophila) 3 185915906-185938136 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011692, HPA063597, HPA064972 Supported Enhanced Nucleoplasm Ovarian cancer:2.15e-4 (favourable), Liver cancer:8.51e-4 (unfavourable) Expressed in all Expressed in all appendix: 56.6 Expressed in all +SCN2A HBSCI, HBSCII, Nav1.2, SCN2A1, SCN2A2 ENSG00000136531 Sodium voltage-gated channel alpha subunit 2 2 165194993-165392310 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB022567 Enhanced Tissue enhanced Tissue enriched 26 cerebral cortex: 56.6 kidney: 2.1 Cell line enhanced U-138 MG: 3.6;U-266/84: 5.7;U-87 MG: 2.2 +TBR1 ENSG00000136535 T-box, brain 1 2 161416094-161425870 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051256, HPA078644, HPA078657 Enhanced Approved Not detected Tissue enriched 30 cerebral cortex: 30.6 testis: 1.0 Not detected +MARCH7 AXOT, MARCH-VII, RNF177 ENSG00000136536 Membrane associated ring-CH-type finger 7 2 159712457-159771027 Enzymes, Predicted intracellular proteins Evidence at protein level HPA014275, HPA022152 Enhanced Supported Plasma membrane
Cytosol Renal cancer:1.84e-4 (unfavourable), Liver cancer:2.41e-4 (unfavourable) Expressed in all Expressed in all testis: 113.1 Expressed in all +ERMN ERMIN, JN, KIAA1189 ENSG00000136541 Ermin 2 157318625-157327713 Predicted intracellular proteins Evidence at protein level HPA038295, HPA038296 Enhanced Endometrial cancer:6.93e-6 (favourable) Group enriched Tissue enriched 27 cerebral cortex: 227.8 bone marrow: 8.3 Cell line enriched 8 HAP1: 20.7 +GALNT5 GalNAc-T5 ENSG00000136542 Polypeptide N-acetylgalactosaminyltransferase 5 2 157257598-157314211 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008963, HPA009035 Approved Approved Nucleoli
Golgi apparatus
Vesicles
Cytosol Mixed Tissue enhanced lung: 18.4;rectum: 19.7;stomach: 16.8 colon: 13.9 Cell line enhanced A-431: 60.2;BJ hTERT+: 63.9;fHDF/TERT166: 72.0;HaCaT: 69.5;LHCN-M2: 65.2 +SCN7A NaG, Nav2.1, Nav2.2, SCN6A ENSG00000136546 Sodium voltage-gated channel alpha subunit 7 2 166403573-166494247 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA004879 Uncertain Mixed Tissue enhanced ovary: 63.2 lung: 41.1 Not detected +TANK I-TRAF, TRAF2 ENSG00000136560 TRAF family member associated NFKB activator 2 161136908-161236221 Predicted intracellular proteins Evidence at protein level CAB010345, HPA037675, HPA037676 Approved Supported Nucleoli
Cytosol Renal cancer:2.78e-6 (unfavourable), Liver cancer:2.90e-4 (unfavourable) Expressed in all Expressed in all breast: 68.2 Expressed in all +BLK MGC10442 ENSG00000136573 BLK proto-oncogene, Src family tyrosine kinase 8 11494001-11564604 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005093, HPA069571 Approved Approved Nucleoplasm Mixed Group enriched 10 appendix: 22.0;lymph node: 61.2;spleen: 40.6;tonsil: 51.4 urinary bladder: 4.3 Group enriched 6 Daudi: 99.9;REH: 39.4;RPMI-8226: 47.4;U-698: 55.4;U-87 MG: 29.9 +GATA4 ENSG00000136574 GATA binding protein 4 8 11676959-11760002 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB013125, HPA073899 Uncertain Supported Nuclear bodies Tissue enhanced Tissue enhanced duodenum: 72.5;heart muscle: 59.0;ovary: 111.8 testis: 51.5 Cell line enhanced HEK 293: 11.9;Hep G2: 21.2;HHSteC: 31.6;SH-SY5Y: 45.2 +SKIL SNO, SnoA, SnoN ENSG00000136603 SKI like proto-oncogene 3 170357678-170396835 Predicted intracellular proteins Evidence at protein level HPA008472 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.19e-7 (unfavourable) Expressed in all Expressed in all gallbladder: 36.9 Expressed in all +EPRS EARS, GLUPRORS, PARS, QARS, QPRS ENSG00000136628 Glutamyl-prolyl-tRNA synthetase 1 219968601-220046658 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026490, HPA030052 Enhanced Enhanced Cytosol Urothelial cancer:2.62e-4 (unfavourable), Breast cancer:7.25e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 120.4 Expressed in all +HLX HB24, HLX1 ENSG00000136630 H2.0 like homeobox 1 220879400-220885059 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005968 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:7.28e-6 (unfavourable) Expressed in all Tissue enhanced bone marrow: 60.3 lung: 27.1 Cell line enhanced THP-1: 72.2 +VPS45 h-vps45, H1, VPS45A, VPS45B ENSG00000136631 Vacuolar protein sorting 45 homolog 1 150067293-150145327 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027425, HPA027441 Uncertain Approved Microtubules Liver cancer:6.57e-6 (unfavourable), Renal cancer:1.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 37.6 Expressed in all +IL10 CSIF, IL-10, IL10A, TGIF ENSG00000136634 Interleukin 10 1 206767602-206772494 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB013120 Uncertain Mixed Tissue enhanced appendix: 8.7 adipose tissue: 7.4 Group enriched 7 HMC-1: 5.2;U-266/70: 6.5 +KCTD3 NY-REN-45 ENSG00000136636 Potassium channel tetramerization domain containing 3 1 215567392-215621807 Predicted intracellular proteins Evidence at protein level HPA015142 Approved Approved Cytosol Renal cancer:8.94e-6 (unfavourable), Pancreatic cancer:4.71e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 103.7 Expressed in all +RPS6KC1 humS6PKh1 ENSG00000136643 Ribosomal protein S6 kinase C1 1 213051233-213274773 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026531, HPA031565 Approved Enhanced Endosomes
Lysosomes
Cytosol Renal cancer:2.70e-4 (unfavourable) Expressed in all Expressed in all testis: 35.4 Expressed in all +CBWD2 ENSG00000136682 COBW domain containing 2 2 113437691-113496189 Predicted intracellular proteins Evidence at transcript level HPA042759, HPA042813 Approved Approved Plasma membrane Endometrial cancer:3.22e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 18.9 Expressed in all +IL36G IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1 ENSG00000136688 Interleukin 36, gamma 2 112973203-112985665 Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 10 skin: 15.8;tonsil: 39.2 esophagus: 2.7 Not detected +IL1RN ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430 ENSG00000136689 Interleukin 1 receptor antagonist 2 113107214-113134016 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001482, CAB009633 Enhanced Renal cancer:2.66e-6 (unfavourable), Endometrial cancer:3.00e-4 (unfavourable), Pancreatic cancer:6.85e-4 (unfavourable), Testis cancer:8.23e-4 (unfavourable) Expressed in all Tissue enhanced esophagus: 1243.9 tonsil: 290.5 Cell line enhanced A-431: 51.8;HaCaT: 100.6;RT4: 89.4 +IL36A FIL1, FIL1E, IL-1F6, IL1(EPSILON), IL1F6, MGC129552, MGC129553 ENSG00000136694 Interleukin 36, alpha 2 113005461-113008044 Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 1237 esophagus: 459.4;tonsil: 105.4 endometrium: 0.2 Cell line enhanced MOLT-4: 1.0 +IL36RN FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840 ENSG00000136695 Interleukin 36 receptor antagonist 2 113058638-113065382 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034542 Uncertain Tissue enriched Group enriched 7 esophagus: 17.2;skin: 40.7;tonsil: 38.1 placenta: 4.7 Group enriched 18 BEWO: 25.1;U-87 MG: 19.4 +IL36B FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882 ENSG00000136696 Interleukin 36, beta 2 113022091-113052867 Predicted intracellular proteins Evidence at transcript level HPA035664 Uncertain Tissue enhanced Tissue enhanced esophagus: 2.2;skin: 7.3;tonsil: 3.4 breast: 1.2 Cell line enriched 21 U-87 MG: 71.9 +IL1F10 FKSG75, IL-1F10, IL-1HY2, IL1-theta, MGC11983, MGC119832, MGC119833 ENSG00000136697 Interleukin 1 family member 10 (theta) 2 113067970-113075850 Predicted intracellular proteins Evidence at protein level HPA059813 Approved Tissue enhanced Group enriched 5 skin: 4.8;tonsil: 2.5 breast: 0.7 Not detected +CFC1 CRYPTIC, HTX2 ENSG00000136698 Cripto, FRL-1, cryptic family 1 2 130592168-130599575 Disease related genes, Predicted secreted proteins Evidence at protein level HPA041773 Uncertain Tissue enriched Tissue enhanced pancreas: 4.1;prostate: 10.4;stomach: 8.0 fallopian tube: 1.6 Group enriched 18 RPMI-8226: 13.6;SCLC-21H: 12.6 +SMPD4 FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3 ENSG00000136699 Sphingomyelin phosphodiesterase 4 2 130151392-130182750 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046279, HPA049426 Approved Approved Nuclear membrane
Cytosol Renal cancer:8.16e-8 (unfavourable), Liver cancer:8.37e-6 (unfavourable), Endometrial cancer:7.47e-5 (unfavourable), Prostate cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all testis: 36.0 Expressed in all +WDR33 FLJ11294, NET14, WDC146 ENSG00000136709 WD repeat domain 33 2 127701022-127811187 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026897, HPA046527 Supported Supported Nucleoplasm
Nucleoli fibrillar center Liver cancer:2.13e-4 (unfavourable) Expressed in all Expressed in all testis: 38.2 Expressed in all +CCDC115 ccp1, FLJ30131, MGC12981 ENSG00000136710 Coiled-coil domain containing 115 2 130338241-130342349 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034598 Approved Supported Vesicles
Plasma membrane Breast cancer:7.59e-4 (favourable) Expressed in all Expressed in all ovary: 55.5 Expressed in all +SAP130 FLJ12761 ENSG00000136715 Sin3A associated protein 130 2 127941217-128028120 Predicted intracellular proteins Evidence at protein level HPA034664 Supported Nuclear speckles Liver cancer:7.89e-4 (unfavourable) Expressed in all Expressed in all testis: 86.9 Expressed in all +BIN1 AMPH2, AMPHL, SH3P9 ENSG00000136717 Bridging integrator 1 2 127048027-127107355 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB001945, HPA003894, HPA005437 Enhanced Supported Cytosol Expressed in all Group enriched 7 cerebral cortex: 156.4;skeletal muscle: 724.1 adrenal gland: 61.4 Mixed +IMP4 BXDC4, MGC19606 ENSG00000136718 IMP4 homolog, U3 small nucleolar ribonucleoprotein 2 130342225-130347810 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA066222, HPA066673 Enhanced Nucleoli Liver cancer:4.72e-4 (unfavourable) Expressed in all Mixed lymph node: 22.7 Expressed in all +HS6ST1 HS6ST ENSG00000136720 Heparan sulfate 6-O-sulfotransferase 1 2 128236716-128318577 Disease related genes, Predicted secreted proteins Evidence at protein level HPA044586 Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 40.8 Expressed in all +UGGT1 HUGT1, UGCGL1 ENSG00000136731 UDP-glucose glycoprotein glucosyltransferase 1 2 128091200-128195677 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012761, HPA015127 Enhanced Uncertain Cytosol Renal cancer:6.37e-4 (unfavourable) Expressed in all Expressed in all epididymis: 24.3 Expressed in all +GYPC CD236, CD236R, Ge, GPC, GYPD ENSG00000136732 Glycophorin C (Gerbich blood group) 2 126655933-126696675 Blood group antigen proteins, CD markers, Predicted membrane proteins Evidence at protein level HPA008965, CAB009445 Enhanced Approved Vesicles
Cytosol Expressed in all Expressed in all bone marrow: 229.7 Cell line enhanced HHSteC: 315.4;SK-MEL-30: 452.6 +STAM STAM1 ENSG00000136738 Signal transducing adaptor molecule 10 17644125-17715914 Predicted intracellular proteins Evidence at protein level CAB034399, HPA043882 Supported Supported Vesicles Liver cancer:3.44e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 41.9 Expressed in all +GAD2 GAD65 ENSG00000136750 Glutamate decarboxylase 2 10 26216307-26304558 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044637, CAB078177 Enhanced Group enriched Tissue enriched 17 cerebral cortex: 22.9 pancreas: 1.3 Group enriched 13 MOLT-4: 2.4;SCLC-21H: 7.4 +ABI1 ABI-1, E3B1, SSH3BP1 ENSG00000136754 Abl interactor 1 10 26746593-26861087 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB008375, HPA029973, HPA068407 Approved Supported Plasma membrane
Cell Junctions Expressed in all Expressed in all cerebral cortex: 87.4 Expressed in all +YME1L1 ENSG00000136758 YME1 like 1 ATPase 10 27110112-27155266 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066953 Approved Supported Nuclear bodies
Mitochondria Liver cancer:8.25e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 105.7 Expressed in all +DNAJC1 DNAJL1, ERdj1, MTJ1 ENSG00000136770 DnaJ heat shock protein family (Hsp40) member C1 10 21756537-22003769 Predicted membrane proteins, Transcription factors Evidence at protein level HPA013432 Approved Approved Endoplasmic reticulum Liver cancer:1.96e-5 (unfavourable), Renal cancer:2.33e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 57.8 Expressed in all +NIPSNAP3A DKFZp564D177, FLJ13953, HSPC299, MGC14553 ENSG00000136783 Nipsnap homolog 3A 9 104747688-104760122 Predicted intracellular proteins Evidence at protein level HPA042491 Approved Expressed in all Expressed in all adrenal gland: 50.9 Expressed in all +LRRC8A FLJ10337, KIAA1437, LRRC8, SWELL1 ENSG00000136802 Leucine rich repeat containing 8 family member A 9 128882112-128918039 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:5.27e-5 (favourable), Pancreatic cancer:3.83e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 89.7 Expressed in all +CDK9 C-2k, CDC2L4, PITALRE, TAK ENSG00000136807 Cyclin dependent kinase 9 9 127785679-127790787 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004216, HPA006738 Supported Approved Nucleoplasm
Cytoplasmic bodies Renal cancer:8.92e-4 (unfavourable) Expressed in all Expressed in all ovary: 60.5 Expressed in all +TXN TRX ENSG00000136810 Thioredoxin 9 110243811-110256640 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008678, HPA047478, HPA055752 Enhanced Enhanced Nucleus
Nucleoli
Cytosol Endometrial cancer:3.40e-6 (favourable) Expressed in all Expressed in all esophagus: 702.9 Expressed in all +ODF2 CT134, ODF84 ENSG00000136811 Outer dense fiber of sperm tails 2 9 128455186-128501292 Predicted intracellular proteins Evidence at protein level HPA001874, HPA048841 Enhanced Supported Centrosome Liver cancer:1.58e-4 (unfavourable), Prostate cancer:1.72e-4 (unfavourable) Expressed in all Tissue enriched 15 testis: 535.2 fallopian tube: 36.6 Expressed in all +KIAA0368 ECM29, FLJ22036 ENSG00000136813 KIAA0368 9 111360692-111484745 Predicted intracellular proteins Evidence at protein level HPA021646, HPA059795 Uncertain Supported Nucleus Expressed in all Expressed in all parathyroid gland: 80.8 Mixed +TOR1B DQ1, MGC4386 ENSG00000136816 Torsin family 1 member B 9 129803153-129811281 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA013403, HPA013697, CAB022709 Approved Approved Nuclear speckles
Cytosol Expressed in all Expressed in all rectum: 24.4 Expressed in all +C9orf78 HCA59, HSPC220 ENSG00000136819 Chromosome 9 open reading frame 78 9 129827290-129835863 Predicted intracellular proteins Evidence at protein level HPA021216, HPA021232, HPA021242 Enhanced Enhanced Nucleoplasm Renal cancer:3.49e-7 (favourable) Expressed in all Expressed in all bone marrow: 71.1 Expressed in all +SMC2 CAP-E, hCAP-E, SMC2L1 ENSG00000136824 Structural maintenance of chromosomes 2 9 104094260-104141417 Predicted intracellular proteins Evidence at protein level HPA071309 Approved Supported Nucleus
Nucleoli Expressed in all Mixed testis: 22.2 Expressed in all +KLF4 EZF, GKLF ENSG00000136826 Kruppel like factor 4 9 107484852-107490482 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002926 Enhanced Supported Nucleoplasm Renal cancer:3.93e-5 (favourable) Expressed in all Expressed in all esophagus: 128.5 Cell line enhanced hTCEpi: 66.2;U-2197: 130.0 +TOR1A DQ2, DYT1 ENSG00000136827 Torsin family 1 member A 9 129812944-129824134 Disease related genes, Predicted secreted proteins Evidence at protein level CAB012473, HPA051195 Approved Supported Nuclear membrane
Vesicles Lung cancer:5.45e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 39.9 Expressed in all +RALGPS1 KIAA0351, RALGEF2, RALGPS1A ENSG00000136828 Ral GEF with PH domain and SH3 binding motif 1 9 126914774-127223166 Predicted intracellular proteins Evidence at protein level Renal cancer:6.20e-11 (favourable) Expressed in all Expressed in all small intestine: 32.0 Mixed +FAM129B bA356B19.6, C9orf88, DKFZP434H0820, FLJ13518, FLJ22151, FLJ22298, MINERVA ENSG00000136830 Family with sequence similarity 129 member B 9 127505339-127578989 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021284, HPA021417, HPA023261, HPA024312 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all esophagus: 362.3 Mixed +OR1J1 hg32 ENSG00000136834 Olfactory receptor family 1 subfamily J member 1 9 122476958-122477926 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR13C9 ENSG00000136839 Olfactory receptor family 13 subfamily C member 9 9 104617248-104618204 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ST6GALNAC4 SIAT3C, SIAT7D, ST6GALNACIV ENSG00000136840 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 9 127907886-127917038 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009042 Approved Nucleus
Golgi apparatus Liver cancer:8.63e-7 (unfavourable), Ovarian cancer:5.12e-4 (unfavourable), Renal cancer:8.39e-4 (unfavourable) Expressed in all Mixed bone marrow: 24.4 Cell line enhanced HDLM-2: 98.1;RPMI-8226: 103.5 +TMOD1 D9S57E, ETMOD, TMOD ENSG00000136842 Tropomodulin 1 9 97501180-97601748 Predicted intracellular proteins Evidence at protein level HPA051202 Enhanced Approved Cytosol Tissue enhanced Mixed heart muscle: 93.4 Group enriched 7 EFO-21: 35.5;HDLM-2: 143.0;K-562: 47.3;SH-SY5Y: 166.4 +DAB2IP AF9Q34, AIP1, DIP1/2, KIAA1743 ENSG00000136848 DAB2 interacting protein 9 121567057-121785530 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.00e-15 (favourable) Expressed in all Mixed testis: 33.8 Cell line enhanced HaCaT: 72.1 +STXBP1 hUNC18, MUNC18-1, rbSec1, UNC18 ENSG00000136854 Syntaxin binding protein 1 9 127579370-127696027 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008209, HPA023483, CAB034434 Enhanced Approved Nucleoplasm
Cytosol Head and neck cancer:1.47e-4 (unfavourable), Endometrial cancer:4.78e-4 (unfavourable), Liver cancer:5.73e-4 (unfavourable), Pancreatic cancer:9.81e-4 (favourable) Expressed in all Tissue enriched 8 cerebral cortex: 396.3 fallopian tube: 52.6 Cell line enhanced SCLC-21H: 169.1 +SLC2A8 GLUT8, GLUTX1 ENSG00000136856 Solute carrier family 2 member 8 9 127397138-127408424 Predicted membrane proteins, Transporters Evidence at protein level HPA011935 Uncertain Approved Vesicles Cervical cancer:2.57e-6 (favourable), Renal cancer:6.55e-6 (favourable), Pancreatic cancer:9.86e-6 (favourable) Expressed in all Expressed in all testis: 50.0 Cell line enhanced CACO-2: 101.8 +ANGPTL2 ARP2, HARP ENSG00000136859 Angiopoietin like 2 9 127087332-127122883 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040933, HPA041299 Approved Approved Golgi apparatus Renal cancer:3.32e-5 (unfavourable) Expressed in all Mixed adipose tissue: 114.9 Cell line enhanced ASC diff: 96.3;ASC TERT1: 66.5;BJ hTERT+: 165.9;HSkMC: 70.1 +CDK5RAP2 C48, CEP215, FLJ10867, MCPH3 ENSG00000136861 CDK5 regulatory subunit associated protein 2 9 120388869-120580170 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035820, HPA046529 Approved Enhanced Cell Junctions
Centrosome Expressed in all Expressed in all testis: 37.4 Expressed in all +ZFP37 ZNF906 ENSG00000136866 ZFP37 zinc finger protein 9 113038380-113056759 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA049112 Uncertain Approved Nucleus
Vesicles Glioma:9.22e-5 (favourable) Mixed Mixed ovary: 8.8 Mixed +SLC31A2 COPT2, CTR2, hCTR2 ENSG00000136867 Solute carrier family 31 member 2 9 113150942-113164137 Predicted membrane proteins, Transporters Evidence at protein level HPA014861 Approved Approved Nuclear speckles
Plasma membrane
Intermediate filaments Mixed Expressed in all salivary gland: 169.9 Cell line enhanced hTCEpi: 59.3 +SLC31A1 COPT1, CTR1, hCTR1 ENSG00000136868 Solute carrier family 31 member 1 9 113221562-113264492 Predicted membrane proteins, Transporters Evidence at protein level HPA013810 Approved Renal cancer:2.20e-6 (favourable), Thyroid cancer:2.03e-4 (unfavourable) Expressed in all Expressed in all liver: 56.5 Expressed in all +TLR4 ARMD10, CD284, hToll, TLR-4 ENSG00000136869 Toll like receptor 4 9 117704332-117716871 CD markers, Predicted membrane proteins Evidence at protein level CAB004025, HPA049174 Approved Supported Golgi apparatus
Cytosol Testis cancer:3.79e-4 (unfavourable), Endometrial cancer:6.29e-4 (favourable) Expressed in all Mixed spleen: 48.3 Cell line enhanced Karpas-707: 40.8;TIME: 38.1 +ZNF189 ENSG00000136870 Zinc finger protein 189 9 101398873-101410660 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034814 Uncertain Approved Intermediate filaments Renal cancer:5.32e-4 (favourable) Expressed in all Expressed in all epididymis: 104.7 Expressed in all +ALDOB ENSG00000136872 Aldolase, fructose-bisphosphate B 9 101420578-101435823 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002198, CAB020827 Enhanced Tissue enriched Group enriched 23 duodenum: 3705.7;kidney: 6574.8;liver: 5092.2;small intestine: 5611.2 gallbladder: 231.1 Cell line enhanced BEWO: 16.8;NB-4: 10.8;RPMI-8226: 13.6;SH-SY5Y: 17.3 +STX17 FLJ20651 ENSG00000136874 Syntaxin 17 9 99906633-99970341 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001204 Approved Uncertain Nucleoli
Cytosol Renal cancer:1.62e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 35.7 Expressed in all +PRPF4 HPRP4, HPRP4P, PRP4, Prp4p, SNRNP60 ENSG00000136875 Pre-mRNA processing factor 4 9 113275343-113292905 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021794, HPA022248 Enhanced Enhanced Nuclear speckles Liver cancer:9.35e-4 (unfavourable) Expressed in all Expressed in all epididymis: 24.3 Expressed in all +FPGS ENSG00000136877 Folylpolyglutamate synthase 9 127794597-127814327 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA050488 Approved Endometrial cancer:9.08e-4 (favourable) Expressed in all Expressed in all fallopian tube,ovary: 26.1 Expressed in all +USP20 KIAA1003 ENSG00000136878 Ubiquitin specific peptidase 20 9 129834698-129881838 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006287, HPA007008 Uncertain Approved Approved Nucleus
Plasma membrane
Cytosol Pancreatic cancer:1.54e-7 (favourable), Renal cancer:5.65e-5 (favourable), Colorectal cancer:2.48e-4 (unfavourable), Endometrial cancer:4.01e-4 (favourable), Cervical cancer:8.01e-4 (favourable) Expressed in all Expressed in all thyroid gland: 22.1 Expressed in all +BAAT BAT ENSG00000136881 Bile acid-CoA:amino acid N-acyltransferase 9 101360417-101383519 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021251, HPA021330 Supported Uncertain Vesicles Renal cancer:4.24e-7 (unfavourable), Liver cancer:4.97e-4 (favourable) Tissue enriched Tissue enriched 16 liver: 340.4 gallbladder: 21.1 Cell line enhanced A549: 1.8 +KIF12 ENSG00000136883 Kinesin family member 12 9 114086126-114099291 Predicted intracellular proteins Evidence at protein level HPA020192, HPA024127 Uncertain Approved Nucleoplasm Mixed Tissue enhanced gallbladder: 36.6;kidney: 46.9 thyroid gland: 33.0 Cell line enhanced CACO-2: 6.3;RPTEC TERT1: 31.9;SCLC-21H: 7.6 +ATP6V1G1 ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10 ENSG00000136888 ATPase H+ transporting V1 subunit G1 9 114587746-114598373 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004615, HPA042898 Supported Supported Nucleus
Nucleoli Renal cancer:1.73e-7 (favourable) Expressed in all Expressed in all epididymis: 301.0 Expressed in all +TEX10 bA208F1.2, FLJ20287, Ipi1 ENSG00000136891 Testis expressed 10 9 100302077-100352939 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Liver cancer:4.46e-5 (unfavourable) Expressed in all Expressed in all testis: 41.6 Expressed in all +GARNL3 bA356B19.1, DKFZp761J1523 ENSG00000136895 GTPase activating Rap/RanGAP domain like 3 9 127224265-127393660 Predicted intracellular proteins Evidence at protein level HPA022433, HPA028757, HPA074886 Uncertain Approved Vesicles Mixed Mixed parathyroid gland: 15.5 Cell line enhanced SH-SY5Y: 3.7 +MRPL50 FLJ20493, MRP-L50 ENSG00000136897 Mitochondrial ribosomal protein L50 9 101387633-101398614 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA022925, HPA056854 Approved Supported Vesicles
Cytosol Renal cancer:1.21e-10 (favourable) Expressed in all Expressed in all adrenal gland: 20.8 Expressed in all +DPM2 MGC111193, MGC21559 ENSG00000136908 Dolichyl-phosphate mannosyltransferase subunit 2, regulatory 9 127935099-127938484 Disease related genes, Predicted membrane proteins Evidence at protein level HPA064623 Approved Endometrial cancer:2.20e-4 (favourable), Liver cancer:7.08e-4 (unfavourable) Expressed in all Mixed fallopian tube,stomach: 24.8 Expressed in all +WDR38 ENSG00000136918 WD repeat domain 38 9 124853417-124857890 Predicted intracellular proteins Evidence at transcript level HPA056607 Uncertain Endometrial cancer:3.97e-4 (favourable) Tissue enhanced Tissue enriched 17 fallopian tube: 125.2 lung: 7.3 Not detected +TSTD2 C9orf97, PP4189 ENSG00000136925 Thiosulfate sulfurtransferase like domain containing 2 9 97600080-97633575 Predicted intracellular proteins Evidence at protein level HPA022537, HPA024241, HPA064304 Uncertain Approved Nucleoplasm Renal cancer:5.75e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.9 Expressed in all +GABBR2 GABABR2, GPR51, GPRC3B, HG20 ENSG00000136928 Gamma-aminobutyric acid type B receptor subunit 2 9 98288082-98709197 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA013820, HPA031684, CAB079065 Enhanced Approved Group enriched Tissue enriched 18 cerebral cortex: 77.9 adrenal gland: 4.3 Cell line enhanced BJ: 11.3;HUVEC TERT2: 22.8;U-138 MG: 10.3 +HEMGN CT155, EDAG, NDR ENSG00000136929 Hemogen 9 97926791-97944856 Predicted intracellular proteins Evidence at protein level HPA019572, HPA019604, HPA019606 Enhanced Not detected Group enriched 14 bone marrow: 141.7;testis: 88.2 placenta: 8.1 Group enriched 7 HEL: 54.8;K-562: 247.2 +PSMB7 ENSG00000136930 Proteasome subunit beta 7 9 124353466-124415444 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052408, HPA054902 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 236.9 Expressed in all +NR5A1 AD4BP, ELP, FTZ1, FTZF1, hSF-1, SF-1 ENSG00000136931 Nuclear receptor subfamily 5 group A member 1 9 124481236-124507430 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Group enriched Group enriched 6 adrenal gland: 137.7;ovary: 36.3;spleen: 151.6 testis: 19.6 Group enriched 31 HEL: 73.5;Hep G2: 36.2;K-562: 17.7 +TRMO C9orf156, HSPC219 ENSG00000136932 TRNA methyltransferase O 9 97904489-97922570 Predicted intracellular proteins Evidence at protein level HPA021281, HPA052197 Approved Approved Nucleoplasm Renal cancer:4.81e-10 (favourable) Expressed in all Expressed in all thyroid gland: 29.7 Expressed in all +RABEPK bA65N13.1, RAB9P40 ENSG00000136933 Rab9 effector protein with kelch motifs 9 125200542-125234158 Predicted intracellular proteins Evidence at protein level HPA023920, HPA067106 Enhanced Uncertain Plasma membrane Expressed in all Expressed in all liver: 30.6 Expressed in all +GOLGA1 golgin-97, MGC33154 ENSG00000136935 Golgin A1 9 124878357-124948492 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013065, HPA044329, HPA050555 Enhanced Enhanced Golgi apparatus Endometrial cancer:2.21e-4 (favourable) Expressed in all Expressed in all testis: 28.8 Expressed in all +XPA XP1, XPAC ENSG00000136936 XPA, DNA damage recognition and repair factor 9 97674909-97697357 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB000155, HPA056856 Supported Approved Nucleus
Cytokinetic bridge Renal cancer:4.28e-5 (favourable) Expressed in all Expressed in all thyroid gland: 38.9 Expressed in all +NCBP1 CBP80, NCBP, Sto1 ENSG00000136937 Nuclear cap binding protein subunit 1 9 97633626-97673748 Predicted intracellular proteins, Transporters Evidence at protein level HPA042411, HPA049031 Enhanced Supported Nucleoplasm
Cytosol Prostate cancer:4.17e-4 (unfavourable), Colorectal cancer:5.28e-4 (favourable) Expressed in all Expressed in all testis: 31.5 Expressed in all +ANP32B APRIL, PHAPI2, SSP29 ENSG00000136938 Acidic nuclear phosphoprotein 32 family member B 9 97983361-98015943 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063133, HPA067561 Supported Enhanced Nucleoplasm
Centrosome
Cytosol Liver cancer:1.98e-7 (unfavourable) Expressed in all Expressed in all lymph node: 264.3 Expressed in all +OR1L4 OR1L5, OR9-E ENSG00000136939 Olfactory receptor family 1 subfamily L member 4 9 122723990-122724925 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +PDCL DKFZp564M1863, PhLP ENSG00000136940 Phosducin like 9 122798389-122828631 Predicted intracellular proteins Evidence at protein level HPA021571, HPA021647, CAB026473 Uncertain Supported Cytosol Renal cancer:7.00e-4 (favourable) Expressed in all Expressed in all endometrium: 23.9 Mixed +RPL35 L35 ENSG00000136942 Ribosomal protein L35 9 124857880-124861981 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA006047 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 2747.0 Expressed in all +CTSV CTSL2, CTSU ENSG00000136943 Cathepsin V 9 97029679-97039643 Enzymes, Predicted secreted proteins Evidence at protein level CAB017112 Uncertain Approved Nucleus
Nucleoli fibrillar center
Plasma membrane
Cytosol Liver cancer:2.83e-5 (unfavourable), Urothelial cancer:2.39e-4 (unfavourable), Pancreatic cancer:2.87e-4 (unfavourable), Endometrial cancer:8.41e-4 (favourable) Mixed Tissue enhanced cervix, uterine: 69.3;skin: 64.2;testis: 131.8 placenta: 25.9 Cell line enriched 7 BEWO: 563.7 +LMX1B NPS1 ENSG00000136944 LIM homeobox transcription factor 1 beta 9 126614443-126701032 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA073716 Approved Nucleus Tissue enriched Tissue enhanced breast: 5.8;salivary gland: 11.2 testis: 2.2 Cell line enhanced MCF7: 13.7;T-47d: 10.1 +ARPC5L ARC16-2, MGC3038 ENSG00000136950 Actin related protein 2/3 complex subunit 5 like 9 124862130-124877733 Predicted intracellular proteins Evidence at protein level HPA022013 Approved Expressed in all Expressed in all testis: 75.7 Expressed in all +ENPP2 ATX, PD-IALPHA, PDNP2 ENSG00000136960 Ectonucleotide pyrophosphatase/phosphodiesterase 2 8 119557086-119673453 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023700, HPA053652 Approved Approved Nucleus
Golgi apparatus
Actin filaments Pancreatic cancer:2.07e-5 (favourable) Expressed in all Expressed in all placenta: 376.2 Cell line enhanced ASC TERT1: 231.1;BJ hTERT+: 160.8 +DSCC1 DCC1, hDCC1, MGC5528 ENSG00000136982 DNA replication and sister chromatid cohesion 1 8 119833976-119856010 Predicted intracellular proteins Evidence at protein level HPA023780, HPA024401 Uncertain Approved Nucleoplasm Liver cancer:3.92e-6 (unfavourable), Lung cancer:3.93e-4 (unfavourable), Melanoma:5.73e-4 (unfavourable) Expressed in all Mixed lymph node: 7.9 Expressed in all +DERL1 DER-1, DER1, derlin-1, FLJ13784, MGC3067, PRO2577 ENSG00000136986 Derlin 1 8 123013164-123042423 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA016562, CAB037269 Enhanced Enhanced Endoplasmic reticulum Endometrial cancer:5.66e-5 (unfavourable), Renal cancer:1.58e-4 (unfavourable), Breast cancer:2.43e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 76.8 Expressed in all +MYC bHLHe39, c-Myc, MYCC ENSG00000136997 V-myc avian myelocytomatosis viral oncogene homolog 8 127735434-127741434 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000084, CAB010307, HPA055893, HPA066556 Supported Enhanced Nucleoplasm Renal cancer:5.49e-8 (unfavourable), Urothelial cancer:4.96e-5 (unfavourable), Ovarian cancer:7.52e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 151.6 Expressed in all +NOV CCN3, IGFBP9 ENSG00000136999 Nephroblastoma overexpressed 8 119416306-119424353 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA018449, HPA019684, CAB034423 Enhanced Supported Vesicles Expressed in all Tissue enriched 39 adrenal gland: 1392.1 prostate: 35.4 Cell line enhanced BJ hTERT+: 99.0;U-2197: 116.0 +IL33 C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV ENSG00000137033 Interleukin 33 9 6215786-6257983 Predicted intracellular proteins Evidence at protein level CAB007057, HPA024426 Supported Breast cancer:4.42e-4 (favourable) Expressed in all Mixed placenta: 87.7 Cell line enriched 10 U-2197: 151.4 +TMEM261 C9orf123, MGC4730 ENSG00000137038 Transmembrane protein 261 9 7796490-7888380 Predicted membrane proteins Evidence at protein level HPA014585 Approved Renal cancer:1.96e-11 (favourable), Endometrial cancer:4.15e-4 (favourable) Expressed in all Expressed in all thyroid gland: 17.3 Expressed in all +RANBP6 ENSG00000137040 RAN binding protein 6 9 6011043-6015625 Predicted intracellular proteins Evidence at protein level HPA043748, HPA052684 Approved Supported Vesicles Renal cancer:1.34e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 26.2 Expressed in all +POLR1E FLJ13390, FLJ13970, PAF53, PRAF1 ENSG00000137054 RNA polymerase I subunit E 9 37485935-37503697 Predicted intracellular proteins, Predicted membrane proteins, RNA polymerase related proteins Evidence at protein level HPA022527, HPA052400 Supported Supported Nucleus
Nucleoli fibrillar center Breast cancer:2.27e-4 (favourable) Expressed in all Expressed in all ovary: 51.5 Expressed in all +PLAA DOA1, FLJ11281, FLJ12699, PLA2P, PLAP ENSG00000137055 Phospholipase A2 activating protein 9 26904083-26947463 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005035, HPA020994, HPA020996 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Ovarian cancer:7.87e-4 (favourable) Expressed in all Expressed in all testis: 37.9 Mixed +IL11RA ENSG00000137070 Interleukin 11 receptor subunit alpha 9 34650702-34661892 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013162, CAB032830, HPA036652 Supported Renal cancer:6.56e-4 (unfavourable) Expressed in all Expressed in all skin: 72.6 Mixed +UBAP2 bA176F3.5, FLJ22435, KIAA1491 ENSG00000137073 Ubiquitin associated protein 2 9 33921693-34048949 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021684 Approved Approved Cytosol Liver cancer:3.45e-6 (unfavourable), Renal cancer:1.95e-4 (favourable), Ovarian cancer:8.59e-4 (favourable) Expressed in all Expressed in all testis: 46.6 Expressed in all +APTX AOA, AOA1, AXA1, EAOH, EOAHA, FLJ20157 ENSG00000137074 Aprataxin 9 32972606-33025168 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064930 Supported Enhanced Nucleus
Nucleoli Renal cancer:6.01e-5 (favourable) Expressed in all Expressed in all testis: 24.5 Expressed in all +RNF38 ENSG00000137075 Ring finger protein 38 9 36336396-36487548 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015853 Approved Supported Nucleoplasm Renal cancer:2.90e-6 (favourable) Expressed in all Expressed in all testis: 116.8 Expressed in all +TLN1 ILWEQ, TLN ENSG00000137076 Talin 1 9 35696948-35732395 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002006, HPA004748 Supported Supported Plasma membrane
Focal adhesion sites
Microtubule organizing center
Cytosol Colorectal cancer:5.56e-4 (unfavourable), Renal cancer:7.21e-4 (favourable) Expressed in all Expressed in all smooth muscle: 204.8 Expressed in all +CCL21 6Ckine, CKb9, ECL, exodus-2, SCYA21, SLC, TCA4 ENSG00000137077 C-C motif chemokine ligand 21 9 34709005-34710124 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB005067, HPA051210 Enhanced Mixed Tissue enhanced lymph node: 3155.9 tonsil: 946.7 Cell line enhanced K-562: 1.0 +SIT1 SIT ENSG00000137078 Signaling threshold regulating transmembrane adaptor 1 9 35649295-35650950 Predicted membrane proteins Evidence at protein level HPA018506 Enhanced Endometrial cancer:1.94e-6 (favourable), Renal cancer:1.75e-5 (unfavourable), Head and neck cancer:1.14e-4 (favourable), Cervical cancer:6.56e-4 (favourable), Melanoma:8.17e-4 (favourable) Mixed Group enriched 5 appendix: 24.6;lymph node: 56.1;spleen: 21.9;tonsil: 29.6 urinary bladder: 6.0 Cell line enhanced Daudi: 80.3;HDLM-2: 65.0;U-698: 70.1 +IFNA21 IFN-alphaI ENSG00000137080 Interferon alpha 21 9 21165637-21166660 Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected lymph node: 0.1 Not detected +DMRT1 CT154, DMT1 ENSG00000137090 Doublesex and mab-3 related transcription factor 1 9 841690-969090 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027850 Enhanced Tissue enriched Tissue enriched 107 testis: 50.7 thyroid gland: 0.4 Cell line enriched 8 SCLC-21H: 3.8 +DNAJB5 Hsc40 ENSG00000137094 DnaJ heat shock protein family (Hsp40) member B5 9 34989641-34998900 Predicted intracellular proteins Evidence at protein level HPA023818, HPA050794 Approved Approved Nucleus
Cytosol Expressed in all Mixed smooth muscle: 92.2 Mixed +SPAG8 BS-84, CT142, HSD-1, hSMP-1, SPAG3 ENSG00000137098 Sperm associated antigen 8 9 35808045-35812272 Predicted intracellular proteins Evidence at protein level HPA068012 Enhanced Endometrial cancer:2.15e-4 (favourable) Mixed Group enriched 10 fallopian tube: 28.6;testis: 16.3 thyroid gland: 2.2 Not detected +DCTN3 DCTN-22 ENSG00000137100 Dynactin subunit 3 9 34613545-34620523 Predicted intracellular proteins Evidence at protein level HPA044905 Approved Supported Nucleoli
Cytosol Renal cancer:5.76e-11 (favourable), Ovarian cancer:2.10e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 129.7 Expressed in all +CD72 CD72b, LYB2 ENSG00000137101 CD72 molecule 9 35609533-35646810 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002505, HPA044658 Enhanced Approved Nucleus
Mitochondria Renal cancer:2.49e-8 (unfavourable) Expressed in all Group enriched 8 appendix: 25.1;lymph node: 71.1;spleen: 64.7;tonsil: 42.6 gallbladder: 6.2 Cell line enhanced Daudi: 13.0;Karpas-707: 8.1;REH: 7.0;U-698: 27.7 +TMEM8B C9orf127, NAG-5, NGX6 ENSG00000137103 Transmembrane protein 8B 9 35814451-35854847 Predicted membrane proteins, Transporters Evidence at protein level HPA052130, HPA062701 Approved Approved Vesicles Renal cancer:1.89e-15 (favourable), Pancreatic cancer:3.14e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.1 Mixed +GRHPR GLXR, PH2 ENSG00000137106 Glyoxylate and hydroxypyruvate reductase 9 37422666-37436990 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA022971 Approved Approved Nucleoplasm
Cytosol Renal cancer:5.39e-9 (favourable), Breast cancer:7.00e-5 (favourable) Expressed in all Expressed in all liver: 323.3 Expressed in all +ALDH1B1 ALDH5, ALDHX ENSG00000137124 Aldehyde dehydrogenase 1 family member B1 9 38392664-38398661 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021037 Approved Supported Nucleoplasm
Vesicles
Mitochondria Thyroid cancer:1.17e-5 (unfavourable), Renal cancer:2.05e-4 (favourable) Expressed in all Expressed in all smooth muscle: 178.4 Mixed +HINT2 ENSG00000137133 Histidine triad nucleotide binding protein 2 9 35812960-35815354 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA020961, HPA059109 Enhanced Enhanced Mitochondria Renal cancer:2.97e-9 (favourable), Ovarian cancer:1.66e-4 (favourable) Expressed in all Expressed in all kidney: 83.2 Expressed in all +ARHGEF39 C9orf100, FLJ14642 ENSG00000137135 Rho guanine nucleotide exchange factor 39 9 35658875-35675866 Predicted intracellular proteins Evidence at protein level HPA061299 Uncertain Ovarian cancer:4.48e-4 (favourable) Mixed Mixed lymph node: 2.3 Mixed +IGFBPL1 bA113O24.1 ENSG00000137142 Insulin like growth factor binding protein like 1 9 38408994-38424447 Predicted secreted proteins Evidence at protein level HPA051354 Uncertain Approved Nucleoplasm
Vesicles Mixed Tissue enriched 8 thyroid gland: 31.5 cerebral cortex: 3.9 Group enriched 6 AF22: 359.4;NTERA-2: 100.5;RH-30: 101.1;SCLC-21H: 438.6;SH-SY5Y: 383.3 +DENND4C bA513M16.3, C9orf55, C9orf55B, FLJ20686, RAB10GEF ENSG00000137145 DENN domain containing 4C 9 19230435-19373545 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014917, HPA015096 Approved Supported Golgi apparatus
Vesicles
Cytosol Renal cancer:3.51e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 47.6 Expressed in all +RPS6 S6 ENSG00000137154 Ribosomal protein S6 9 19375715-19380254 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level CAB004027, HPA031153 Supported Enhanced Endoplasmic reticulum
Cytosol Endometrial cancer:4.12e-4 (favourable) Expressed in all Expressed in all ovary: 4805.4 Expressed in all +CNPY3 CAG4A, TNRC5 ENSG00000137161 Canopy FGF signaling regulator 3 6 42929192-42939287 Predicted secreted proteins Evidence at protein level HPA016560 Uncertain Renal cancer:9.85e-6 (unfavourable), Colorectal cancer:3.03e-5 (unfavourable) Expressed in all Expressed in all spleen: 103.1 Expressed in all +FOXP4 FLJ40908 ENSG00000137166 Forkhead box P4 6 41546426-41602384 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007176 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:1.17e-6 (unfavourable), Liver cancer:9.72e-4 (unfavourable) Expressed in all Expressed in all stomach: 36.9 Expressed in all +PPIL1 CYPL1 ENSG00000137168 Peptidylprolyl isomerase like 1 6 36854827-36875024 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062916 Approved Nucleoli Liver cancer:1.28e-5 (unfavourable), Ovarian cancer:4.90e-4 (favourable) Expressed in all Expressed in all thyroid gland: 42.0 Expressed in all +KLC4 bA387M24.3, KNSL8 ENSG00000137171 Kinesin light chain 4 6 43040777-43075099 Predicted intracellular proteins Evidence at protein level HPA030168, HPA030169 Enhanced Approved Mitochondria
Cytosol Renal cancer:6.99e-6 (favourable) Expressed in all Expressed in all duodenum: 70.0 Expressed in all +KIF13A bA500C11.2 ENSG00000137177 Kinesin family member 13A 6 17759183-17987623 Predicted intracellular proteins Evidence at protein level HPA029253, HPA029254 Uncertain Liver cancer:5.06e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.3 Mixed +ZSCAN9 PRD51, ZNF193 ENSG00000137185 Zinc finger and SCAN domain containing 9 6 28224886-28233482 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054512, HPA059951 Uncertain Approved Nucleoplasm Renal cancer:1.21e-6 (unfavourable), Urothelial cancer:1.16e-5 (favourable), Liver cancer:3.49e-4 (unfavourable) Expressed in all Expressed in all testis: 34.8 Mixed +PIM1 PIM ENSG00000137193 Pim-1 proto-oncogene, serine/threonine kinase 6 37170203-37175426 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA003941, CAB017040 Uncertain Supported Nucleoli
Cytosol Endometrial cancer:9.73e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 133.9 Expressed in all +GMPR ENSG00000137198 Guanosine monophosphate reductase 6 16238580-16295549 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000904, HPA021476 Uncertain Renal cancer:2.94e-5 (favourable), Ovarian cancer:2.06e-4 (favourable), Lung cancer:8.07e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 105.7 Cell line enhanced HEL: 171.8;HMC-1: 275.3 +CMTR1 FTSJD2, ISG95, KIAA0082, MTr1 ENSG00000137200 Cap methyltransferase 1 6 37433219-37482827 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029954, HPA029979, HPA029980 Enhanced Enhanced Nucleoplasm
Cytosol Endometrial cancer:1.73e-5 (unfavourable) Expressed in all Expressed in all testis: 85.5 Expressed in all +TFAP2A AP-2, AP2TF, TFAP2 ENSG00000137203 Transcription factor AP-2 alpha 6 10393186-10419659 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000326, HPA028850, HPA056871 Enhanced Enhanced Nucleoplasm Lung cancer:1.09e-4 (unfavourable) Tissue enhanced Tissue enhanced breast: 40.0;placenta: 42.3;skin: 76.1 epididymis: 24.9 Cell line enhanced HDLM-2: 103.3 +SLC22A7 NLT, OAT2 ENSG00000137204 Solute carrier family 22 member 7 6 43295694-43305538 Predicted membrane proteins, Transporters Evidence at protein level HPA030220 Approved Liver cancer:5.48e-6 (favourable), Renal cancer:8.98e-4 (favourable) Tissue enriched Group enriched 73 kidney: 50.3;liver: 167.8 testis: 1.4 Cell line enriched 14 Hep G2: 6.7 +YIPF3 C6orf109, dJ337H4.3, DKFZp566C243, FinGER3, KLIP1 ENSG00000137207 Yip1 domain family member 3 6 43511827-43516990 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014859, HPA063699 Supported Enhanced Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 142.8 Expressed in all +TMEM14B MGC1223 ENSG00000137210 Transmembrane protein 14B 6 10747759-10852753 Predicted membrane proteins Evidence at protein level Liver cancer:9.35e-5 (unfavourable), Endometrial cancer:6.51e-4 (unfavourable), Ovarian cancer:7.41e-4 (favourable) Expressed in all Expressed in all thyroid gland: 205.0 Expressed in all +TMEM63B C6orf110, dJ421H19.2, DKFZp434P0531 ENSG00000137216 Transmembrane protein 63B 6 44126914-44155519 Predicted membrane proteins, Transporters Evidence at protein level HPA029249, HPA029250, HPA029251 Uncertain Enhanced Plasma membrane
Actin filaments Expressed in all Expressed in all lung: 59.0 Expressed in all +FRS3 FRS2B, FRS2beta, SNT-2 ENSG00000137218 Fibroblast growth factor receptor substrate 3 6 41770176-41786542 Predicted intracellular proteins Evidence at protein level HPA030162, HPA030174 Enhanced Uncertain Nucleoplasm Pancreatic cancer:3.87e-4 (favourable) Expressed in all Mixed testis: 22.0 Expressed in all +TJAP1 PILT, TJP4 ENSG00000137221 Tight junction associated protein 1 6 43477523-43506556 Predicted intracellular proteins Evidence at protein level HPA030164, HPA030165, HPA030166 Supported Approved Golgi apparatus Liver cancer:9.02e-6 (unfavourable), Renal cancer:1.13e-4 (unfavourable) Expressed in all Expressed in all endometrium: 33.8 Expressed in all +CAPN11 ENSG00000137225 Calpain 11 6 44158811-44184402 Enzymes, Predicted intracellular proteins Evidence at protein level CAB018070, HPA030955 Enhanced Not detected Tissue enriched 33 testis: 54.8 adipose tissue,breast: 1.6 Group enriched 5 NTERA-2: 2.2;TIME: 4.7 +TINAG ENSG00000137251 Tubulointerstitial nephritis antigen 6 54307859-54390152 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035427 Approved Liver cancer:2.05e-5 (unfavourable), Renal cancer:8.75e-5 (favourable) Tissue enhanced Tissue enriched 7 kidney: 113.9 small intestine: 15.7 Cell line enriched 36 RPTEC TERT1: 69.3 +HCRTR2 OX2R ENSG00000137252 Hypocretin receptor 2 6 55106460-55282620 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA054516 Supported Not detected Not detected kidney: 0.6 Cell line enriched 7 AF22: 1.0 +KIAA0319 NMIG ENSG00000137261 KIAA0319 6 24544104-24646155 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015607, HPA076313 Enhanced Uncertain Vesicles Mixed Tissue enriched 6 cerebral cortex: 15.8 fallopian tube: 2.8 Cell line enhanced HDLM-2: 2.6;SCLC-21H: 5.1;U-266/84: 2.6 +IRF4 LSIRF, MUM1 ENSG00000137265 Interferon regulatory factor 4 6 391739-411447 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002038, HPA002698, CAB013508 Enhanced Supported Nucleoplasm Head and neck cancer:1.64e-6 (favourable), Breast cancer:6.44e-4 (favourable) Tissue enriched Tissue enhanced lymph node: 27.1 tonsil: 24.1 Group enriched 5 HDLM-2: 204.2;Karpas-707: 141.1;RPMI-8226: 136.6;U-266/70: 134.4;U-266/84: 98.3;U-698: 40.9;WM-115: 106.9 +SLC22A23 C6orf85, FLJ22174 ENSG00000137266 Solute carrier family 22 member 23 6 3268962-3457022 Predicted membrane proteins, Transporters Evidence at protein level HPA014697 Approved Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:2.39e-4 (unfavourable), Endometrial cancer:6.57e-4 (favourable) Expressed in all Expressed in all stomach: 27.9 Mixed +TUBB2A dJ40E16.7, TUBB, TUBB2 ENSG00000137267 Tubulin beta 2A class IIa 6 3153669-3157526 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015339, HPA043640, HPA046280 Supported Supported Microtubules Urothelial cancer:1.61e-4 (unfavourable), Renal cancer:4.65e-4 (favourable) Expressed in all Tissue enriched 9 cerebral cortex: 622.8 skin: 72.0 Expressed in all +LRRC1 dJ523E19.1, FLJ10775, FLJ11834, LANO ENSG00000137269 Leucine rich repeat containing 1 6 53794497-53924121 Predicted intracellular proteins Evidence at protein level HPA031603, HPA031604 Enhanced Supported Cytosol Renal cancer:2.21e-7 (favourable), Pancreatic cancer:1.18e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 41.9 Mixed +GCM1 GCMA, hGCMa ENSG00000137270 Glial cells missing homolog 1 6 53126964-53148829 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA011343 Enhanced Approved Vesicles Not detected Tissue enriched 21 placenta: 29.1 kidney: 1.3 Cell line enriched 25 BEWO: 38.0 +FOXF2 FKHL6, FREAC2 ENSG00000137273 Forkhead box F2 6 1389834-1395597 Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Mixed lung: 18.4 Cell line enhanced BJ hTERT+: 64.9;HEK 293: 24.6;U-2197: 30.0 +BPHL Bph-rp, MCNAA, VACVase ENSG00000137274 Biphenyl hydrolase like 6 3118374-3153578 Predicted intracellular proteins Evidence at protein level HPA036752, HPA036753 Enhanced Supported Mitochondria Renal cancer:5.16e-7 (favourable), Ovarian cancer:5.97e-4 (favourable) Expressed in all Expressed in all kidney: 112.2 Expressed in all +RIPK1 RIP ENSG00000137275 Receptor interacting serine/threonine kinase 1 6 3063991-3115187 Enzymes, Predicted intracellular proteins Evidence at protein level CAB010302, HPA015257 Enhanced Enhanced Plasma membrane
Cytosol Urothelial cancer:6.71e-4 (favourable) Expressed in all Expressed in all skin: 26.1 Expressed in all +TUBB2B bA506K6.1, DKFZp566F223, MGC8685 ENSG00000137285 Tubulin beta 2B class IIb 6 3224261-3231730 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043640, HPA046280 Supported Endometrial cancer:1.94e-4 (unfavourable) Tissue enriched Tissue enriched 6 cerebral cortex: 308.7 epididymis: 51.8 Cell line enhanced AF22: 504.0;CACO-2: 319.1;SCLC-21H: 896.6;SH-SY5Y: 392.2 +UQCC2 bA6B20.2, C6orf125, Cbp6, M19, MGC14833, MNF1 ENSG00000137288 Ubiquinol-cytochrome c reductase complex assembly factor 2 6 33694293-33711727 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039111 Uncertain Supported Nuclear bodies
Mitochondria Expressed in all Expressed in all testis: 131.3 Expressed in all +HMGA1 HMGIY ENSG00000137309 High mobility group AT-hook 1 6 34236873-34246231 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB032200 Uncertain Approved Nucleus
Nucleoli Liver cancer:1.29e-6 (unfavourable), Lung cancer:3.36e-4 (unfavourable), Endometrial cancer:7.13e-4 (unfavourable), Pancreatic cancer:8.71e-4 (unfavourable) Expressed in all Expressed in all lymph node: 163.8 Expressed in all +TCF19 SC1 ENSG00000137310 Transcription factor 19 6 31158542-31167159 Predicted intracellular proteins Evidence at protein level Renal cancer:3.54e-10 (unfavourable), Liver cancer:5.66e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 11.3 skin: 6.7 Cell line enhanced A-431: 72.1;HEK 293: 41.2;SCLC-21H: 57.4;U-138 MG: 47.7 +FLOT1 ENSG00000137312 Flotillin 1 6 30727709-30742733 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001393, CAB007766 Enhanced Approved Golgi apparatus
Vesicles
Plasma membrane Renal cancer:1.49e-4 (unfavourable), Ovarian cancer:3.06e-4 (favourable), Colorectal cancer:5.78e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 18.9 Expressed in all +IER3 DIF-2, IEX-1, IEX-1L, PRG1 ENSG00000137331 Immediate early response 3 6 30743199-30744554 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043847 Approved Renal cancer:3.10e-7 (unfavourable), Liver cancer:6.36e-5 (unfavourable), Head and neck cancer:5.57e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 20.7 adipose tissue: 11.4 Group enriched 6 A-431: 133.8;EFO-21: 51.6;HBEC3-KT: 133.4;RPTEC TERT1: 150.4 +MDC1 Em:AB023051.5, KIAA0170, NFBD1 ENSG00000137337 Mediator of DNA damage checkpoint 1 6 30699807-30717889 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA006915 Enhanced Supported Nucleoplasm
Nuclear bodies Expressed in all Tissue enhanced testis: 9.6 skin: 3.3 Cell line enhanced A-431: 21.4;HEK 293: 41.5 +PGBD1 dJ874C20.4, HUCEP-4, SCAND4 ENSG00000137338 PiggyBac transposable element derived 1 6 28281572-28302549 Predicted intracellular proteins Evidence at protein level HPA007267 Uncertain Approved Nucleoplasm
Cytosol Melanoma:1.71e-4 (unfavourable), Liver cancer:3.77e-4 (unfavourable), Renal cancer:4.97e-4 (unfavourable), Pancreatic cancer:6.79e-4 (favourable) Expressed in all Mixed smooth muscle: 7.9 Mixed +ATAT1 C6orf134, Em:AB023049.7, FLJ13158, MEC17 ENSG00000137343 Alpha tubulin acetyltransferase 1 6 30626842-30646823 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046816, HPA050999 Approved Approved Golgi apparatus
Cytosol Liver cancer:1.03e-5 (unfavourable), Renal cancer:7.78e-5 (unfavourable), Urothelial cancer:1.35e-4 (favourable) Expressed in all Mixed epididymis: 4.4 Cell line enhanced AF22: 7.3 +TPMT ENSG00000137364 Thiopurine S-methyltransferase 6 18128311-18155074 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA019851 Approved Endometrial cancer:8.45e-5 (unfavourable), Renal cancer:1.10e-4 (favourable), Ovarian cancer:1.41e-4 (favourable) Expressed in all Expressed in all thyroid gland: 129.8 Expressed in all +CLPS ENSG00000137392 Colipase 6 35794982-35797344 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA010512 Enhanced Tissue enriched Tissue enriched 264 pancreas: 56632.1 ovary: 214.3 Not detected +RNF144B bA528A10.3, IBRDC2 ENSG00000137393 Ring finger protein 144B 6 18387350-18468874 Predicted membrane proteins Evidence at protein level CAB046013, HPA054127, HPA072469 Uncertain Approved Nucleoli
Mitochondria Expressed in all Tissue enhanced thyroid gland: 68.1 breast: 35.0 Cell line enhanced Daudi: 137.5;U-698: 110.9 +NRM NRM29 ENSG00000137404 Nurim (nuclear envelope membrane protein) 6 30688047-30691420 Predicted membrane proteins Evidence at protein level HPA072545, HPA073982 Enhanced Nuclear membrane Renal cancer:3.52e-8 (unfavourable) Expressed in all Mixed skin,smooth muscle: 1.6 Mixed +MTCH1 CGI-64, PSAP, SLC25A49 ENSG00000137409 Mitochondrial carrier 1 6 36968141-36986298 Predicted membrane proteins, Transporters Evidence at protein level HPA015971 Approved Renal cancer:1.16e-7 (favourable), Liver cancer:1.17e-4 (unfavourable), Endometrial cancer:2.06e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 569.1 Expressed in all +VARS2 DKFZP434L1435, G7a, KIAA1885, VARS2L, VARSL ENSG00000137411 Valyl-tRNA synthetase 2, mitochondrial 6 30908242-30926459 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA062449, HPA070267 Approved Approved Mitochondria Expressed in all Mixed esophagus: 5.2 Mixed +TAF8 FLJ32821, TAF(II)43, TBN ENSG00000137413 TATA-box binding protein associated factor 8 6 42050513-42087461 Predicted intracellular proteins Evidence at protein level HPA031730, HPA031731, HPA031734 Supported Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 24.3 Expressed in all +FAM8A1 AHCP ENSG00000137414 Family with sequence similarity 8 member A1 6 17600355-17611719 Predicted membrane proteins, Transporters Evidence at protein level HPA044698, HPA073675 Approved Approved Golgi apparatus Expressed in all Expressed in all endometrium: 45.5 Expressed in all +C6orf52 ENSG00000137434 Chromosome 6 open reading frame 52 6 10671418-10694797 Predicted intracellular proteins Evidence at transcript level HPA051142 Uncertain Approved Nuclear speckles Endometrial cancer:6.50e-5 (favourable) Mixed Tissue enhanced testis: 18.0 fallopian tube: 10.5 Mixed +FGFBP1 FGFBP, HBP17 ENSG00000137440 Fibroblast growth factor binding protein 1 4 15935569-15938740 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA004332 Enhanced Pancreatic cancer:5.03e-4 (unfavourable) Tissue enhanced Tissue enriched 7 esophagus: 297.8 skin: 40.2 Cell line enhanced CAPAN-2: 164.8;HaCaT: 489.2;HBEC3-KT: 688.5 +FGFBP2 KSP37 ENSG00000137441 Fibroblast growth factor binding protein 2 4 15960243-15969309 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA039180 Uncertain Group enriched Tissue enhanced bone marrow: 29.0 spleen: 18.0 Cell line enhanced SK-MEL-30: 4.8;T-47d: 2.8;WM-115: 1.2 +CPEB2 ENSG00000137449 Cytoplasmic polyadenylation element binding protein 2 4 15002674-15070153 Predicted intracellular proteins Evidence at protein level HPA072513 Approved Cytosol Expressed in all Tissue enhanced testis: 41.7 parathyroid gland: 20.5 Cell line enhanced RPTEC TERT1: 26.5 +FHDC1 KIAA1727 ENSG00000137460 FH2 domain containing 1 4 152936352-152979696 Predicted intracellular proteins Evidence at protein level HPA008527 Uncertain Renal cancer:1.33e-5 (favourable) Mixed Tissue enhanced thyroid gland: 26.8 lung: 12.9 Cell line enhanced BEWO: 29.6;SK-BR-3: 10.8;WM-115: 10.5 +TLR2 CD282, TIL4 ENSG00000137462 Toll like receptor 2 4 153701500-153705699 CD markers, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA060231, HPA071546 Supported Nucleus
Mitochondria Renal cancer:1.11e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 52.7 bone marrow: 34.8 Cell line enhanced RT4: 8.5;THP-1: 25.3 +MGARP C4orf49, CESP-1, HUMMR, OSAP ENSG00000137463 Mitochondria localized glutamic acid rich protein 4 139266163-139280338 Predicted membrane proteins Evidence at protein level HPA015994 Enhanced Supported Mitochondria Tissue enhanced Tissue enriched 10 adrenal gland: 267.2 ovary: 27.1 Cell line enhanced BJ: 15.5;fHDF/TERT166: 21.3;HHSteC: 17.8;HUVEC TERT2: 46.0 +TTC29 NYD-SP14 ENSG00000137473 Tetratricopeptide repeat domain 29 4 146706638-146945882 Predicted intracellular proteins Evidence at protein level HPA037006, HPA061473 Uncertain Tissue enhanced Group enriched 27 fallopian tube: 34.2;testis: 151.1 lung: 3.4 Cell line enhanced ASC TERT1: 3.4;hTERT-HME1: 1.2;U-266/70: 1.6;U-87 MG: 1.0 +MYO7A DFNA11, DFNB2, NSRD2, USH1B ENSG00000137474 Myosin VIIA 11 77128264-77215239 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028918, CAB034059 Uncertain Approved Cytosol Renal cancer:3.07e-4 (unfavourable) Expressed in all Tissue enhanced adrenal gland: 26.8;placenta: 20.8 testis: 17.2 Cell line enhanced BEWO: 11.1;RH-30: 20.1;RPMI-8226: 9.7;SK-BR-3: 8.1;U-937: 11.1 +FCHSD2 KIAA0769, SH3MD3 ENSG00000137478 FCH and double SH3 domains 2 11 72836745-73142261 Predicted intracellular proteins Evidence at protein level HPA038545, HPA038546 Uncertain Approved Nuclear speckles
Plasma membrane
Actin filaments
Focal adhesion sites Colorectal cancer:1.71e-4 (favourable) Expressed in all Expressed in all spleen: 64.1 Expressed in all +ARRB1 ARR1 ENSG00000137486 Arrestin beta 1 11 75264182-75351705 Predicted intracellular proteins Evidence at protein level CAB003763, HPA049318, HPA070249 Approved Supported Nucleoplasm Expressed in all Expressed in all lung: 80.4 Cell line enhanced HEL: 151.4;RH-30: 109.6 +SLCO2B1 OATP-B, OATP2B1, SLC21A9 ENSG00000137491 Solute carrier organic anion transporter family member 2B1 11 75100563-75206549 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA020659 Uncertain Expressed in all Expressed in all liver: 123.1 Cell line enhanced CACO-2: 75.7;HEL: 13.5;Hep G2: 14.2;HMC-1: 23.5 +THAP12 DAP4, P52rIPK, PRKRIR, THAP0 ENSG00000137492 THAP domain containing 12 11 76349956-76380971 Plasma proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA008758 Approved Approved Nucleoplasm Expressed in all Expressed in all endometrium: 42.8 Expressed in all +ANKRD42 FLJ37874, PPP1R79, SARP ENSG00000137494 Ankyrin repeat domain 42 11 83193739-83260694 Predicted intracellular proteins Evidence at protein level HPA039917 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Tissue enhanced testis: 71.5 fallopian tube: 26.2 Expressed in all +IL18BP IL18BPa ENSG00000137496 Interleukin 18 binding protein 11 71998541-72005715 Predicted secreted proteins Evidence at protein level CAB025980, HPA041061 Enhanced Approved Endoplasmic reticulum Renal cancer:2.93e-6 (unfavourable) Expressed in all Tissue enhanced spleen: 56.2 appendix: 32.8 Mixed +NUMA1 ENSG00000137497 Nuclear mitotic apparatus protein 1 11 72002864-72080693 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019841, HPA019859, HPA029912 Enhanced Enhanced Nucleoplasm Renal cancer:7.92e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 247.9 Expressed in all +CCDC90B MDS011, MDS025 ENSG00000137500 Coiled-coil domain containing 90B 11 83259097-83286407 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011130, HPA011931 Enhanced Enhanced Mitochondria Expressed in all Expressed in all testis: 97.8 Expressed in all +SYTL2 CHR11SYT, exophilin-4, FLJ20163, FLJ21219, KIAA1597, MGC102768, PPP1R151, SGA72M, SLP2 ENSG00000137501 Synaptotagmin like 2 11 85694224-85811159 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA039651 Approved Approved Nucleus
Golgi apparatus
Plasma membrane Colorectal cancer:2.67e-4 (favourable), Urothelial cancer:9.07e-4 (favourable) Mixed Tissue enhanced stomach: 120.5 rectum: 81.4 Cell line enhanced RH-30: 170.2;RPTEC TERT1: 95.1 +RAB30 ENSG00000137502 RAB30, member RAS oncogene family 11 82973133-83071923 Predicted intracellular proteins Evidence at protein level HPA054514, HPA060565 Approved Enhanced Vesicles Expressed in all Expressed in all cerebral cortex,tonsil: 28.4 Cell line enhanced U-698: 116.4 +CREBZF ZF ENSG00000137504 CREB/ATF bZIP transcription factor 11 85659708-85682908 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021526, HPA063652 Uncertain Approved Nucleus
Mitochondria Expressed in all Expressed in all parathyroid gland: 31.7 Expressed in all +LRRC32 D11S833E, GARP ENSG00000137507 Leucine rich repeat containing 32 11 76657524-76670747 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055775, HPA058434 Supported Nucleoplasm Renal cancer:3.93e-5 (unfavourable), Urothelial cancer:2.64e-4 (unfavourable) Expressed in all Expressed in all placenta: 76.4 Group enriched 5 ASC diff: 78.8;ASC TERT1: 49.2;HSkMC: 32.0;HUVEC TERT2: 43.0;U-2197: 100.6 +PRCP HUMPCP, PCP ENSG00000137509 Prolylcarboxypeptidase 11 82823502-82970584 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017065 Approved Renal cancer:2.65e-6 (favourable) Expressed in all Expressed in all placenta: 222.7 Expressed in all +NARS2 DFNB94, FLJ23441, SLM5 ENSG00000137513 Asparaginyl-tRNA synthetase 2, mitochondrial (putative) 11 78435961-78574874 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026793 Supported Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:1.22e-6 (favourable), Ovarian cancer:1.39e-5 (favourable) Expressed in all Expressed in all kidney: 19.8 Expressed in all +RNF121 FLJ11099 ENSG00000137522 Ring finger protein 121 11 71928701-71997597 Predicted membrane proteins Evidence at protein level HPA046041 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Renal cancer:2.72e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 28.5 Expressed in all +MRPL15 HSPC145, L15mt, MRP-L15, MRP-L7, RPML7 ENSG00000137547 Mitochondrial ribosomal protein L15 8 54135210-54147901 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA044425 Enhanced Endometrial cancer:5.37e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 84.8 Expressed in all +PI15 P25TI ENSG00000137558 Peptidase inhibitor 15 8 74824537-74855029 Predicted secreted proteins Evidence at protein level HPA006593, HPA030057 Uncertain Approved Vesicles
Cytosol Group enriched Tissue enhanced appendix: 73.2;prostate: 50.5;smooth muscle: 67.8 endometrium: 33.0 Group enriched 9 AF22: 21.0;SH-SY5Y: 22.2;SK-MEL-30: 22.4;U-266/70: 5.5 +TTPA AVED ENSG00000137561 Alpha tocopherol transfer protein 8 63048553-63086053 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 17 liver: 82.7 rectum: 4.8 Cell line enhanced SK-BR-3: 4.7;U-2 OS: 3.3;U-2197: 3.6 +GGH ENSG00000137563 Gamma-glutamyl hydrolase 8 63015079-63039171 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB019296, HPA025226 Approved Endometrial cancer:3.99e-7 (unfavourable), Lung cancer:1.65e-4 (unfavourable) Expressed in all Tissue enhanced kidney: 90.0 liver: 63.2 Mixed +SLCO5A1 OATP-J, OATP5A1, OATPRP4, SLC21A15 ENSG00000137571 Solute carrier organic anion transporter family member 5A1 8 69667047-69835064 Predicted membrane proteins, Transporters Evidence at transcript level HPA025062 Uncertain Mixed Tissue enhanced prostate: 3.6 skeletal muscle: 2.6 Cell line enhanced HAP1: 5.7;NTERA-2: 3.6;RPMI-8226: 2.5;SCLC-21H: 4.6 +SULF1 hSulf-1, KIAA1077, SULF-1 ENSG00000137573 Sulfatase 1 8 69466624-69660915 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054728 Supported Renal cancer:1.06e-7 (unfavourable) Expressed in all Tissue enhanced smooth muscle: 105.4 prostate: 85.8 Cell line enhanced BJ: 265.6;BJ hTERT+: 341.5;fHDF/TERT166: 405.6;WM-115: 176.0 +TGS1 NCOA6IP, PIMT ENSG00000137574 Trimethylguanosine synthase 1 8 55773142-55825448 Predicted intracellular proteins Evidence at protein level HPA025024, HPA029824 Supported Enhanced Nucleus
Cytosol Endometrial cancer:4.63e-4 (unfavourable) Expressed in all Mixed lymph node: 15.3 Expressed in all +SDCBP MDA-9, SYCL ENSG00000137575 Syndecan binding protein 8 58552924-58582860 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012245, HPA023840 Approved Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all Expressed in all placenta: 365.1 Mixed +NEK1 KIAA1901, NY-REN-55 ENSG00000137601 NIMA related kinase 1 4 169392857-169612629 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020873, HPA040413 Approved Approved Nuclear membrane
Nucleoli Renal cancer:1.42e-4 (favourable) Expressed in all Mixed testis: 21.8 Expressed in all +DDX60 FLJ20035 ENSG00000137628 DExD/H-box helicase 60 4 168216293-168318807 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046952 Approved Supported Intermediate filaments
Cytosol Pancreatic cancer:3.35e-4 (unfavourable) Expressed in all Mixed stomach: 45.7 Cell line enhanced BJ hTERT+ SV40 Large T+: 35.0;BJ hTERT+ SV40 Large T+ RasG12V: 35.2 +NXPE4 C11orf33, FAM55D, FLJ20127 ENSG00000137634 Neurexophilin and PC-esterase domain family member 4 11 114570591-114595762 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042801 Approved Tissue enriched Group enriched 9 colon: 139.6;rectum: 158.4;salivary gland: 38.2 appendix: 11.9 Not detected +SORL1 C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1 ENSG00000137642 Sortilin related receptor 1 11 121452203-121633693 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011500, HPA031321 Uncertain Approved Nucleoplasm
Cell Junctions Renal cancer:1.80e-7 (favourable) Expressed in all Mixed cervix, uterine: 67.8 Cell line enhanced CAPAN-2: 125.3;RT4: 81.2;U-698: 97.2 +TMPRSS4 MT-SP2, TMPRSS3 ENSG00000137648 Transmembrane protease, serine 4 11 118077012-118121890 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006238 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:3.14e-4 (unfavourable) Mixed Tissue enhanced rectum: 77.1;urinary bladder: 77.3 esophagus: 73.8 Group enriched 9 A-431: 25.3;CAPAN-2: 123.9;HaCaT: 53.5;RPTEC TERT1: 73.7;RT4: 99.4 +BUD13 Cwc26, fSAP71, MGC13125 ENSG00000137656 BUD13 homolog 11 116748170-116772988 Predicted intracellular proteins Evidence at protein level HPA038340, HPA038341 Enhanced Enhanced Nucleus Liver cancer:5.07e-5 (unfavourable) Expressed in all Expressed in all testis: 39.5 Expressed in all +TRPC6 FSGS2, TRP6 ENSG00000137672 Transient receptor potential cation channel subfamily C member 6 11 101451564-101872562 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA045098, HPA062164 Approved Approved Nucleoplasm
Cytosol Mixed Tissue enhanced placenta: 30.1 lung: 20.0 Cell line enhanced A549: 4.4;ASC diff: 6.0;BJ hTERT+: 3.9;HEL: 4.3;RPTEC TERT1: 16.5 +MMP7 MPSL1, PUMP-1 ENSG00000137673 Matrix metallopeptidase 7 11 102520508-102530753 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB025869, HPA051358 Supported Approved Nucleoplasm
Vesicles Liver cancer:2.53e-4 (unfavourable), Lung cancer:3.38e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 820.8 breast: 201.7 Cell line enhanced A549: 133.0;CAPAN-2: 715.3;EFO-21: 178.3;RPTEC TERT1: 262.4 +MMP20 ENSG00000137674 Matrix metallopeptidase 20 11 102576835-102625332 Disease related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 6 testis: 1.1 appendix,breast,kidney,tonsil: 0.1 Not detected +MMP27 ENSG00000137675 Matrix metallopeptidase 27 11 102691487-102705806 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level HPA069097 Approved Not detected Group enriched 5 breast: 6.0;skin: 2.8 bone marrow: 0.8 Not detected +C11orf70 MGC13040 ENSG00000137691 Chromosome 11 open reading frame 70 11 102047443-102084560 Predicted intracellular proteins Evidence at protein level HPA038585 Enhanced Approved Centrosome Mixed Tissue enhanced fallopian tube: 46.5;testis: 54.7 epididymis: 13.1 Mixed +DCUN1D5 FLJ32431, MGC2714 ENSG00000137692 Defective in cullin neddylation 1 domain containing 5 11 103062076-103092215 Predicted intracellular proteins Evidence at protein level HPA050863 Approved Approved Nucleus
Nucleoli Liver cancer:2.01e-7 (unfavourable), Ovarian cancer:9.52e-5 (favourable), Prostate cancer:4.12e-4 (unfavourable), Head and neck cancer:4.62e-4 (unfavourable) Expressed in all Expressed in all testis: 34.6 Mixed +YAP1 YAP65 ENSG00000137693 Yes associated protein 1 11 102110461-102233423 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB009370, HPA038885, CAB069915, HPA070359 Enhanced Supported Nucleus
Nucleoli Pancreatic cancer:2.03e-4 (unfavourable) Expressed in all Mixed smooth muscle: 147.1 Mixed +TRIM29 ATDC, FLJ36085 ENSG00000137699 Tripartite motif containing 29 11 120111275-120185529 Predicted intracellular proteins Evidence at protein level HPA020053 Enhanced Supported Nucleoplasm
Intermediate filaments Endometrial cancer:2.88e-4 (unfavourable), Pancreatic cancer:4.46e-4 (unfavourable), Stomach cancer:4.93e-4 (favourable) Tissue enhanced Group enriched 6 esophagus: 400.3;skin: 455.7 tonsil: 68.3 Cell line enhanced HaCaT: 211.2;hTCEpi: 225.5;RT4: 101.2;SiHa: 190.1 +SLC37A4 G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d ENSG00000137700 Solute carrier family 37 member 4 11 119024114-119030906 Predicted membrane proteins Evidence at protein level HPA038939, HPA038940 Enhanced Approved Mitochondria Expressed in all Tissue enhanced kidney: 36.6 duodenum: 30.8 Cell line enhanced HEK 293: 24.3 +BTG4 APRO3, PC3B ENSG00000137707 BTG anti-proliferation factor 4 11 111467526-111512354 Predicted intracellular proteins Evidence at transcript level HPA057157 Approved Endoplasmic reticulum
Golgi apparatus Not detected Tissue enriched 18 testis: 47.5 fallopian tube: 2.6 Cell line enhanced CACO-2: 2.8;Karpas-707: 3.2;U-266/70: 2.3 +POU2F3 Epoc-1, OCT11, PLA-1, Skn-1a ENSG00000137709 POU class 2 homeobox 3 11 120236640-120319944 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019652 Enhanced Thyroid cancer:8.14e-4 (favourable) Mixed Group enriched 11 parathyroid gland: 15.5;skin: 72.3 seminal vesicle: 3.8 Cell line enhanced CAPAN-2: 3.7;SK-BR-3: 2.2;T-47d: 5.2 +RDX DFNB24 ENSG00000137710 Radixin 11 110174880-110296722 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000263, HPA000763, CAB037312 Enhanced Enhanced Plasma membrane Expressed in all Expressed in all adrenal gland: 198.2 Mixed +PPP2R1B PP2A-Abeta, PR65B ENSG00000137713 Protein phosphatase 2 scaffold subunit Abeta 11 111726908-111766427 Predicted intracellular proteins Evidence at protein level CAB004034, HPA018908 Approved Approved Nucleus
Plasma membrane
Centrosome
Cytosol Liver cancer:3.80e-4 (favourable) Expressed in all Expressed in all testis: 98.6 Expressed in all +FDX1 ADX, FDX ENSG00000137714 Ferredoxin 1 11 110429883-110464881 Predicted intracellular proteins Evidence at protein level HPA041630, HPA062087 Enhanced Enhanced Mitochondria Renal cancer:3.58e-7 (favourable), Stomach cancer:2.53e-4 (favourable) Expressed in all Tissue enriched 11 adrenal gland: 387.5 seminal vesicle: 36.5 Expressed in all +C11orf1 FLJ23499 ENSG00000137720 Chromosome 11 open reading frame 1 11 111878935-111885975 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038410, HPA057519 Uncertain Enhanced Nucleoplasm Renal cancer:1.39e-4 (favourable), Endometrial cancer:9.32e-4 (favourable) Expressed in all Expressed in all testis: 104.9 Expressed in all +FXYD6 ENSG00000137726 FXYD domain containing ion transport regulator 6 11 117836976-117877486 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA041334, HPA042284 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:1.05e-5 (unfavourable), Renal cancer:4.38e-5 (favourable), Urothelial cancer:1.60e-4 (unfavourable), Liver cancer:5.87e-4 (favourable), Pancreatic cancer:5.97e-4 (favourable) Tissue enriched Expressed in all cerebral cortex: 696.9 Cell line enhanced AF22: 128.6;HAP1: 89.7;SCLC-21H: 231.1;SH-SY5Y: 118.8 +ARHGAP20 KIAA1391 ENSG00000137727 Rho GTPase activating protein 20 11 110577042-110713189 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038458, HPA038459, HPA076303 Uncertain Approved Mitochondria Mixed Mixed testis: 15.4 Cell line enhanced ASC diff: 16.9;ASC TERT1: 5.7;SiHa: 7.6 +FXYD2 ATP1G1, HOMG2, MGC12372 ENSG00000137731 FXYD domain containing ion transport regulator 2 11 117800844-117828698 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA064218, HPA068838 Supported Approved Mitochondria Renal cancer:3.23e-9 (favourable) Tissue enriched Group enriched 6 gallbladder: 571.3;kidney: 1433.1;salivary gland: 380.4 pancreas: 134.6 Group enriched 24 MOLT-4: 1801.2;RPTEC TERT1: 3683.4 +MMP13 CLG3 ENSG00000137745 Matrix metallopeptidase 13 11 102942995-102955734 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced lung: 1.5;urinary bladder: 1.3 appendix: 0.3 Cell line enhanced HaCaT: 15.8;PC-3: 6.2 +TMPRSS13 MSPL, TMPRSS11 ENSG00000137747 Transmembrane protease, serine 13 11 117900643-117929459 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced skin: 36.4 cervix, uterine,esophagus: 10.5 Cell line enhanced BEWO: 32.1;MCF7: 22.3;SK-BR-3: 36.2;T-47d: 46.4 +CASP1 ICE, IL1BC ENSG00000137752 Caspase 1 11 105025443-105035250 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB002685, HPA003056 Approved Supported Nucleoplasm
Cytosol Renal cancer:3.11e-4 (unfavourable) Expressed in all Mixed small intestine: 139.8 Cell line enhanced BJ hTERT+: 91.3;U-937: 106.2 +CASP5 ICE(rel)III ENSG00000137757 Caspase 5 11 104994235-105023168 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040937 Uncertain Group enriched Group enriched 6 appendix: 20.2;colon: 15.9;duodenum: 10.1;rectum: 14.5;small intestine: 18.9 smooth muscle: 2.7 Cell line enriched 8 HHSteC: 3.1 +ALKBH8 MGC10235, TRM9, TRMT9 ENSG00000137760 AlkB homolog 8, tRNA methyltransferase 11 107502726-107565746 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038724, HPA038725, HPA061514 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Mixed parathyroid gland: 9.6 Expressed in all +MAP2K5 HsT17454, MAPKK5, MEK5, PRKMK5 ENSG00000137764 Mitogen-activated protein kinase kinase 5 15 67542709-67807123 Enzymes, Predicted intracellular proteins Evidence at protein level CAB022094, HPA027347, HPA027755 Supported Approved Nucleoli
Microtubules Renal cancer:8.03e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 32.7 Expressed in all +UNC13C DKFZp547H074, Munc13-3 ENSG00000137766 Unc-13 homolog C 15 54012904-54633414 Predicted intracellular proteins Evidence at protein level HPA041516 Uncertain Not detected Group enriched 15 cerebral cortex: 17.4;testis: 15.3 ovary,thyroid gland: 1.1 Group enriched 9 Karpas-707: 52.9;U-266/70: 74.2 +SQRDL CGI-44 ENSG00000137767 Sulfide quinone reductase-like (yeast) 15 45631148-45691294 Predicted intracellular proteins Evidence at protein level HPA017079, HPA041589 Enhanced Enhanced Mitochondria Endometrial cancer:2.57e-4 (favourable), Lung cancer:8.80e-4 (unfavourable) Expressed in all Expressed in all colon: 193.5 Cell line enhanced HBEC3-KT: 198.5 +CTDSPL2 FLJ10523, HSPC129 ENSG00000137770 CTD small phosphatase like 2 15 44427234-44529038 Predicted intracellular proteins Evidence at protein level HPA040763, HPA062198 Approved Enhanced Nucleoplasm Expressed in all Expressed in all testis: 37.8 Expressed in all +SLTM FLJ13213, Met ENSG00000137776 SAFB like transcription modulator 15 58879045-58933653 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040256, HPA040381 Enhanced Enhanced Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 66.5 Expressed in all +THBS1 THBS, THBS-1, TSP, TSP-1, TSP1 ENSG00000137801 Thrombospondin 1 15 39581079-39599466 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB033678, HPA059756 Approved Approved Plasma membrane Renal cancer:8.47e-5 (unfavourable), Stomach cancer:8.50e-4 (unfavourable) Expressed in all Expressed in all appendix: 573.9 Cell line enhanced fHDF/TERT166: 2033.2;HUVEC TERT2: 2095.4;TIME: 3015.4 +MAPKBP1 KIAA0596 ENSG00000137802 Mitogen-activated protein kinase binding protein 1 15 41774434-41827855 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030832, HPA030833 Enhanced Approved Nucleoli Endometrial cancer:1.47e-4 (favourable), Ovarian cancer:6.80e-4 (unfavourable) Expressed in all Mixed testis: 34.0 Mixed +NUSAP1 ANKT, BM037, FLJ13421, LNP, NuSAP1, PRO0310p1, Q0310, SAPL ENSG00000137804 Nucleolar and spindle associated protein 1 15 41332694-41381050 Predicted intracellular proteins Evidence at protein level HPA042904, HPA074847 Enhanced Enhanced Nucleus
Nucleoli fibrillar center Renal cancer:6.82e-14 (unfavourable), Pancreatic cancer:6.27e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 75.3 lymph node: 57.2 Expressed in all +NDUFAF1 CGI-65, CIA30 ENSG00000137806 NADH:ubiquinone oxidoreductase complex assembly factor 1 15 41387349-41402519 Predicted intracellular proteins Evidence at protein level HPA039933, HPA040064 Supported Enhanced Cytosol Renal cancer:3.34e-6 (favourable), Liver cancer:2.88e-5 (favourable) Expressed in all Expressed in all testis: 45.5 Expressed in all +KIF23 KNSL5, MKLP-1, MKLP1 ENSG00000137807 Kinesin family member 23 15 69414246-69448427 Predicted intracellular proteins Evidence at protein level CAB010414, HPA045208, HPA068831 Approved Enhanced Nucleoplasm Liver cancer:3.18e-5 (unfavourable), Pancreatic cancer:3.69e-5 (unfavourable), Endometrial cancer:8.62e-4 (unfavourable) Mixed Mixed testis: 19.7 Expressed in all +ITGA11 HsT18964 ENSG00000137809 Integrin subunit alpha 11 15 68296533-68432162 Predicted membrane proteins Evidence at protein level HPA051813 Uncertain Renal cancer:3.22e-7 (unfavourable) Mixed Tissue enhanced cervix, uterine: 54.7;endometrium: 52.4;smooth muscle: 75.7 epididymis: 22.9 Cell line enhanced fHDF/TERT166: 203.4;U-138 MG: 173.0;WM-115: 98.4 +KNL1 AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7 ENSG00000137812 Kinetochore scaffold 1 15 40594020-40664342 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026624, HPA049647 Supported Enhanced Nucleoplasm
Nuclear bodies Lung cancer:2.11e-4 (unfavourable) Mixed Tissue enriched 7 testis: 31.7 lymph node: 4.4 Mixed +HAUS2 C15orf25, CEP27, FLJ10460, HsT17025 ENSG00000137814 HAUS augmin like complex subunit 2 15 42548810-42569994 Predicted intracellular proteins Evidence at protein level HPA039965 Approved Approved Nucleoplasm
Centrosome
Cytosol Expressed in all Expressed in all bone marrow: 22.5 Expressed in all +RTF1 KIAA0252 ENSG00000137815 RTF1 homolog, Paf1/RNA polymerase II complex component 15 41408408-41483563 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006714 Approved Approved Nucleus
Cytosol Pancreatic cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 63.5 Expressed in all +PARP6 pART17 ENSG00000137817 Poly(ADP-ribose) polymerase family member 6 15 72241181-72272999 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026991 Approved Approved Plasma membrane Renal cancer:8.02e-8 (unfavourable), Cervical cancer:3.17e-5 (favourable), Colorectal cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all testis: 46.9 Mixed +RPLP1 LP1 ENSG00000137818 Ribosomal protein lateral stalk subunit P1 15 69452784-69456194 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003368 Enhanced Endoplasmic reticulum
Cytosol Renal cancer:2.30e-9 (unfavourable) Expressed in all Expressed in all ovary: 1840.0 Expressed in all +PAQR5 FLJ20190, MPRG ENSG00000137819 Progestin and adipoQ receptor family member 5 15 69298947-69407780 Predicted membrane proteins Evidence at protein level HPA076729 Approved Vesicles Renal cancer:1.47e-14 (favourable), Pancreatic cancer:2.15e-5 (unfavourable) Mixed Tissue enhanced kidney: 55.8 adrenal gland: 20.8 Cell line enhanced A549: 34.9;CAPAN-2: 40.4;HMC-1: 69.7 +LRRC49 FLJ20156 ENSG00000137821 Leucine rich repeat containing 49 15 70853239-71053657 Predicted intracellular proteins Evidence at protein level HPA015596 Uncertain Mixed Mixed heart muscle: 36.4 Cell line enhanced HHSteC: 28.0 +TUBGCP4 76P, FLJ14797 ENSG00000137822 Tubulin gamma complex associated protein 4 15 43369221-43409771 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043212 Approved Supported Centrosome Expressed in all Expressed in all parathyroid gland: 13.1 Expressed in all +RMDN3 FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3 ENSG00000137824 Regulator of microtubule dynamics 3 15 40735884-40755851 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009975 Supported Enhanced Mitochondria Renal cancer:6.70e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 58.1 Expressed in all +ITPKA IP3-3KA, IP3KA ENSG00000137825 Inositol-trisphosphate 3-kinase A 15 41493393-41503551 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040454 Enhanced Approved Approved Vesicles Renal cancer:3.76e-9 (unfavourable), Glioma:5.08e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 25.7;duodenum: 17.7;small intestine: 19.8 stomach: 8.9 Cell line enhanced Hep G2: 22.6 +UACA FLJ10128, KIAA1561 ENSG00000137831 Uveal autoantigen with coiled-coil domains and ankyrin repeats 15 70654554-70763593 Predicted intracellular proteins Evidence at protein level HPA041412, HPA043503 Uncertain Supported Nucleus
Cytosol Pancreatic cancer:7.01e-5 (unfavourable), Urothelial cancer:1.03e-4 (unfavourable), Renal cancer:1.62e-4 (unfavourable) Expressed in all Mixed thyroid gland: 59.6 Cell line enhanced BJ: 206.5 +SMAD6 HsT17432, MADH6, MADH7 ENSG00000137834 SMAD family member 6 15 66702228-66782848 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA061917 Supported Nucleus
Nuclear bodies
Golgi apparatus Urothelial cancer:5.45e-5 (favourable) Expressed in all Tissue enhanced lung: 16.8 placenta: 10.7 Cell line enhanced EFO-21: 28.0 +PLCB2 FLJ38135 ENSG00000137841 Phospholipase C beta 2 15 40278176-40307935 Enzymes, Predicted intracellular proteins Evidence at protein level CAB009443, HPA041298 Approved Approved Cytosol Renal cancer:7.20e-5 (unfavourable), Head and neck cancer:3.00e-4 (favourable) Expressed in all Tissue enhanced spleen: 55.9 appendix: 38.2 Cell line enhanced HEL: 70.2;HMC-1: 82.2;U-937: 41.8 +TMEM62 FLJ23375 ENSG00000137842 Transmembrane protein 62 15 43123279-43185146 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044461, HPA062359 Approved Approved Nucleus
Nucleoli fibrillar center
Nuclear bodies
Cytoplasmic bodies Endometrial cancer:9.72e-7 (favourable) Expressed in all Expressed in all breast: 28.7 Mixed +PAK6 PAK5 ENSG00000137843 P21 (RAC1) activated kinase 6 15 40238759-40277487 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA031124 Approved Approved Nucleus
Nucleoli fibrillar center
Cell Junctions Not detected Mixed cerebral cortex: 28.6 Cell line enhanced CACO-2: 17.4;HaCaT: 28.5;hTCEpi: 13.9 +ADAM10 CD156c, HsT18717, kuz, MADM ENSG00000137845 ADAM metallopeptidase domain 10 15 58588807-58749978 Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB001709, HPA050670 Approved Supported Vesicles
Plasma membrane Lung cancer:8.46e-5 (unfavourable), Pancreatic cancer:1.90e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 47.9 Expressed in all +DUOX1 LNOX1, NOXEF1, THOX1 ENSG00000137857 Dual oxidase 1 15 45129933-45165576 Enzymes, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA023544 Approved Cervical cancer:4.31e-6 (favourable) Tissue enhanced Tissue enhanced skin: 96.9;thyroid gland: 92.6 esophagus: 73.2 Cell line enhanced HaCaT: 56.9;hTCEpi: 22.1;RT4: 29.0 +SLC28A2 CNT2, HCNT2, HsT17153, SPNT1 ENSG00000137860 Solute carrier family 28 member 2 15 45252230-45277845 Predicted membrane proteins, Transporters Evidence at protein level HPA046068, HPA055623 Enhanced Tissue enhanced Tissue enhanced duodenum: 64.9;rectum: 37.1;small intestine: 97.9 stomach: 21.0 Not detected +STRA6 FLJ12541 ENSG00000137868 Stimulated by retinoic acid 6 15 74179466-74212267 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA040839 Approved Approved Nucleus
Cytosol Mixed Tissue enhanced cervix, uterine: 37.0;placenta: 20.4 endometrium: 13.2 Cell line enhanced CAPAN-2: 162.1;SH-SY5Y: 119.5;WM-115: 273.5 +CYP19A1 ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM ENSG00000137869 Cytochrome P450 family 19 subfamily A member 1 15 51208057-51338610 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000355, HPA051194 Enhanced Approved Mitochondria Mixed Tissue enriched 15 placenta: 174.5 adrenal gland: 11.9 Group enriched 6 ASC TERT1: 65.0;HDLM-2: 16.2;HSkMC: 22.8 +ZNF280D FLJ20086, SUHW4, ZNF634 ENSG00000137871 Zinc finger protein 280D 15 56630181-56918571 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030233 Approved Approved Nucleoplasm
Golgi apparatus
Centrosome
Cytosol Expressed in all Expressed in all endometrium: 31.8 Mixed +SEMA6D FLJ11598, KIAA1479 ENSG00000137872 Semaphorin 6D 15 47184101-47774223 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA043109 Approved Golgi apparatus
Plasma membrane Renal cancer:5.96e-5 (favourable) Tissue enhanced Tissue enhanced placenta: 63.6 small intestine: 44.3 Cell line enhanced BJ hTERT+: 12.7;SCLC-21H: 16.1;SH-SY5Y: 13.4 +BCL2L10 BCL-B, Boo, Diva ENSG00000137875 BCL2 like 10 15 52109263-52112775 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042222 Approved Mixed Tissue enhanced skin: 6.1 kidney: 3.3 Group enriched 8 NB-4: 21.5;SiHa: 4.5 +RSL24D1 C15orf15, HRP-L30-iso, L30, RPL24, RPL24L ENSG00000137876 Ribosomal L24 domain containing 1 15 55180806-55197067 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA062724, HPA063392 Enhanced Enhanced Nucleus
Nucleoli Expressed in all Expressed in all ovary: 124.4 Expressed in all +SPTBN5 BSPECV, HUBSPECV, HUSPECV ENSG00000137877 Spectrin beta, non-erythrocytic 5 15 41848144-41894077 Plasma proteins, Predicted intracellular proteins Evidence at protein level Mixed Mixed gallbladder,heart muscle,thyroid gland: 1.3 Cell line enhanced SCLC-21H: 6.0;TIME: 11.0;WM-115: 4.2 +GCOM1 FLJ30973, GRINL1A, MYZAP-POLR2M ENSG00000137878 GRINL1A complex locus 1 15 57591908-57714745 Predicted intracellular proteins Evidence at protein level HPA039827, HPA068141 Approved Approved Nucleoplasm Not detected Mixed heart muscle: 6.2 Cell line enhanced HEL: 29.8;RH-30: 8.7;TIME: 11.5 +GCHFR GFRP, HsT16933 ENSG00000137880 GTP cyclohydrolase I feedback regulator 15 40764020-40767710 Predicted intracellular proteins Evidence at protein level HPA046258 Approved Supported Nucleoplasm Lung cancer:5.62e-4 (favourable) Expressed in all Expressed in all small intestine: 62.4 Cell line enhanced RPTEC TERT1: 101.8;SCLC-21H: 141.5 +BCAR3 NSP2, SH2D3B ENSG00000137936 Breast cancer anti-estrogen resistance 3 1 93561786-93847150 Predicted intracellular proteins Evidence at protein level HPA014858 Approved Approved Plasma membrane
Centrosome
Cytosol Renal cancer:3.08e-7 (favourable), Lung cancer:8.92e-7 (unfavourable), Pancreatic cancer:4.38e-4 (unfavourable), Liver cancer:5.42e-4 (unfavourable), Head and neck cancer:8.41e-4 (unfavourable) Expressed in all Mixed adipose tissue: 32.6 Mixed +TTLL7 FLJ23033 ENSG00000137941 Tubulin tyrosine ligase like 7 1 83865028-83999150 Predicted intracellular proteins Evidence at protein level HPA052249, HPA059321 Uncertain Approved Cytosol Mixed Tissue enhanced cerebral cortex: 46.8 smooth muscle: 10.8 Cell line enhanced HDLM-2: 26.3;RH-30: 21.3;SCLC-21H: 16.4 +FNBP1L C1orf39, FLJ20275, TOCA1 ENSG00000137942 Formin binding protein 1 like 1 93448131-93554661 Predicted intracellular proteins Evidence at protein level HPA065273 Approved Supported Cytosol Renal cancer:4.72e-7 (favourable), Liver cancer:8.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 53.8 Mixed +KYAT3 CCBL2, KAT3, KATIII, RBM1, RP11-82K18.3 ENSG00000137944 Kynurenine aminotransferase 3 1 88935773-88992953 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026538, HPA027168 Enhanced Approved Nucleoli
Cytosol Renal cancer:5.02e-6 (favourable), Breast cancer:3.19e-5 (favourable), Head and neck cancer:1.86e-4 (favourable), Ovarian cancer:2.80e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 42.8 Expressed in all +GTF2B TFIIB ENSG00000137947 General transcription factor IIB 1 88852932-88891944 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA061626 Enhanced Supported Nucleus
Nuclear bodies Breast cancer:4.81e-4 (favourable) Expressed in all Expressed in all bone marrow: 47.6 Expressed in all +BRDT BRD6, CT9 ENSG00000137948 Bromodomain testis associated 1 91949371-92014426 Predicted intracellular proteins Evidence at protein level CAB012237 Approved Group enriched Tissue enriched 124 testis: 235.9 bone marrow: 1.9 Cell line enriched 33 BEWO: 19.0 +RABGGTB ENSG00000137955 Rab geranylgeranyltransferase beta subunit 1 75786197-75795079 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026585, HPA027167, HPA030793 Approved Approved Supported Vesicles Renal cancer:1.12e-5 (unfavourable), Liver cancer:9.80e-5 (unfavourable) Expressed in all Expressed in all kidney: 69.4 Expressed in all +IFI44L C1orf29, GS3686 ENSG00000137959 Interferon induced protein 44 like 1 78619922-78646145 Predicted intracellular proteins Evidence at protein level HPA053247, HPA060372 Enhanced Approved Nucleoplasm Renal cancer:1.06e-4 (unfavourable), Endometrial cancer:2.95e-4 (unfavourable), Glioma:5.08e-4 (favourable) Expressed in all Mixed spleen: 32.4 Cell line enhanced BJ hTERT+ SV40 Large T+: 43.7;BJ hTERT+ SV40 Large T+ RasG12V: 49.2;HSkMC: 19.4;SK-MEL-30: 17.2 +GIPC2 FLJ20075, SEMCAP-2 ENSG00000137960 GIPC PDZ domain containing family member 2 1 77979542-78138449 Predicted intracellular proteins Evidence at protein level HPA051212, HPA062684 Approved Approved Nucleus
Cytosol Renal cancer:2.11e-6 (favourable), Colorectal cancer:5.49e-4 (favourable) Mixed Mixed kidney: 41.6 Cell line enhanced Hep G2: 15.3;HUVEC TERT2: 19.2 +ARHGAP29 PARG1 ENSG00000137962 Rho GTPase activating protein 29 1 94148988-94275068 Predicted intracellular proteins Evidence at protein level HPA026534 Approved Approved Nucleus
Plasma membrane
Centrosome
Cytosol Endometrial cancer:6.26e-5 (unfavourable), Pancreatic cancer:9.63e-4 (unfavourable) Expressed in all Mixed spleen: 49.9 Cell line enhanced A-431: 194.8 +IFI44 MTAP44, p44, TLDC5 ENSG00000137965 Interferon induced protein 44 1 78649796-78664078 Predicted intracellular proteins Evidence at protein level HPA027148, HPA043858 Approved Approved Nucleoplasm Renal cancer:1.37e-8 (unfavourable) Expressed in all Expressed in all spleen: 88.7 Cell line enhanced BJ hTERT+ SV40 Large T+: 163.8;BJ hTERT+ SV40 Large T+ RasG12V: 210.0 +SLC44A5 CTL5, MGC34032 ENSG00000137968 Solute carrier family 44 member 5 1 75202131-75611116 Predicted membrane proteins, Transporters Evidence at protein level HPA047455, HPA051011 Uncertain Approved Cytosol Renal cancer:6.52e-4 (unfavourable) Mixed Tissue enhanced skin: 12.6 parathyroid gland: 8.1 Cell line enhanced SH-SY5Y: 12.2;TIME: 11.9 +CLCA2 CLCRG2 ENSG00000137975 Chloride channel accessory 2 1 86424086-86456558 Predicted membrane proteins Evidence at protein level HPA047192 Enhanced Supported Nucleus
Plasma membrane
Cell Junctions Group enriched Group enriched 5 esophagus: 126.4;skin: 102.7 tonsil: 22.5 Cell line enhanced BEWO: 36.7;HBEC3-KT: 23.7;hTCEpi: 148.8 +DNASE2B DLAD ENSG00000137976 Deoxyribonuclease 2 beta 1 84398532-84415018 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enriched 7 salivary gland: 73.0 prostate: 10.5 Not detected +DBT ENSG00000137992 Dihydrolipoamide branched chain transacylase E2 1 100186919-100249834 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026481, HPA026485, HPA026533 Enhanced Supported Mitochondria Renal cancer:8.79e-12 (favourable) Expressed in all Expressed in all kidney: 19.7 Expressed in all +RTCA RPC, RTC1, RTCD1 ENSG00000137996 RNA 3'-terminal phosphate cyclase 1 100266207-100292769 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027982, HPA027990, HPA028151 Uncertain Enhanced Nucleus Liver cancer:2.76e-5 (unfavourable) Expressed in all Expressed in all kidney: 35.8 Expressed in all +IFT172 BBS20, NPHP17, osm-1, SLB, wim ENSG00000138002 Intraflagellar transport 172 2 27444371-27489789 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044893 Uncertain Approved Vesicles Liver cancer:6.05e-6 (unfavourable) Expressed in all Mixed parathyroid gland: 33.5 Mixed +SELENOI EPT1, KIAA1724, SELI, SEPI ENSG00000138018 Selenoprotein I 2 26308547-26395891 Enzymes, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all parathyroid gland: 33.7 Expressed in all +CGREF1 CGR11 ENSG00000138028 Cell growth regulator with EF-hand domain 1 2 27098889-27119115 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008241 Uncertain Endometrial cancer:3.18e-4 (unfavourable), Liver cancer:7.57e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 44.7 stomach: 11.5 Cell line enhanced SK-BR-3: 58.9 +HADHB MTPB ENSG00000138029 Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2 26243170-26290468 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037539, HPA037540, HPA066099 Enhanced Supported Mitochondria Renal cancer:1.37e-9 (favourable) Expressed in all Expressed in all heart muscle: 300.8 Expressed in all +KHK ENSG00000138030 Ketohexokinase 2 27086747-27100772 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007040 Enhanced Approved Cytosol Endometrial cancer:7.62e-8 (unfavourable) Group enriched Group enriched 11 duodenum: 113.1;kidney: 111.2;liver: 97.3;small intestine: 133.2 cerebral cortex: 10.1 Cell line enhanced Hep G2: 32.5 +ADCY3 AC3 ENSG00000138031 Adenylate cyclase 3 2 24819169-24919839 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB010223 Approved Renal cancer:1.32e-9 (unfavourable) Expressed in all Expressed in all placenta: 122.5 Expressed in all +PPM1B PP2CB, PP2CBETA, PPC2BETAX ENSG00000138032 Protein phosphatase, Mg2+/Mn2+ dependent 1B 2 44167969-44244384 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016745 Approved Approved Nucleoli
Cytosol Expressed in all Expressed in all parathyroid gland: 82.3 Expressed in all +PNPT1 DFNB70, old-35, OLD35, PNPase ENSG00000138035 Polyribonucleotide nucleotidyltransferase 1 2 55634265-55693910 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033424, HPA034602, HPA034603 Supported Enhanced Mitochondria Liver cancer:1.95e-7 (unfavourable), Pancreatic cancer:5.44e-5 (unfavourable), Endometrial cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 9.9 Expressed in all +DYNC2LI1 CGI-60, D2LIC, DKFZP564A033, LIC3 ENSG00000138036 Dynein cytoplasmic 2 light intermediate chain 1 2 43774039-43810010 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA062905 Approved Approved Cytosol Renal cancer:2.73e-5 (favourable) Expressed in all Expressed in all fallopian tube: 86.1 Expressed in all +LHCGR HHG, LCGR, LGR2, LHR, ULG5 ENSG00000138039 Luteinizing hormone/choriogonadotropin receptor 2 48686775-48755730 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009814 Uncertain Not detected Tissue enhanced ovary: 1.6;testis: 4.3 adipose tissue: 1.3 Not detected +THUMPD2 C2orf8, MGC2454 ENSG00000138050 THUMP domain containing 2 2 39736060-39779267 Predicted intracellular proteins Evidence at protein level HPA043042, HPA058025 Approved Uncertain Nucleoplasm Renal cancer:7.27e-5 (unfavourable), Liver cancer:6.05e-4 (unfavourable) Expressed in all Mixed ovary,thyroid gland: 3.8 Mixed +CYP1B1 CP1B, GLC3A ENSG00000138061 Cytochrome P450 family 1 subfamily B member 1 2 38066973-38109902 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB011705, HPA026863 Approved Uncertain Mitochondria Renal cancer:4.39e-6 (unfavourable), Urothelial cancer:2.76e-4 (unfavourable) Expressed in all Mixed fallopian tube: 76.1 Cell line enhanced HSkMC: 400.2;SiHa: 283.9;U-87 MG: 138.5 +SULT6B1 ENSG00000138068 Sulfotransferase family 6B member 1 2 37167820-37196598 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Group enriched 11 fallopian tube: 1.0;testis: 4.3 bone marrow: 0.2 Cell line enriched 6 WM-115: 2.2 +RAB1A RAB1, YPT1 ENSG00000138069 RAB1A, member RAS oncogene family 2 65070701-65130106 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005331, HPA056141 Approved Supported Endoplasmic reticulum
Cytosol Head and neck cancer:4.19e-4 (unfavourable) Expressed in all Expressed in all epididymis: 219.2 Expressed in all +ACTR2 ARP2 ENSG00000138071 ARP2 actin related protein 2 homolog 2 65227753-65271253 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005083, HPA015050 Approved Approved Cytosol Liver cancer:4.50e-4 (unfavourable) Expressed in all Expressed in all appendix: 292.2 Expressed in all +PREB SEC12 ENSG00000138073 Prolactin regulatory element binding 2 27130756-27134675 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013582, HPA014133 Uncertain Approved Endoplasmic reticulum Expressed in all Expressed in all epididymis: 107.6 Expressed in all +SLC5A6 SMVT ENSG00000138074 Solute carrier family 5 member 6 2 27199587-27212958 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA036958 Approved Approved Cell Junctions Renal cancer:3.60e-7 (unfavourable) Expressed in all Expressed in all epididymis: 81.3 Expressed in all +ABCG5 STSL ENSG00000138075 ATP binding cassette subfamily G member 5 2 43812472-43838865 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA016514 Approved Nucleus Liver cancer:2.60e-5 (favourable) Tissue enriched Group enriched 32 duodenum: 56.5;liver: 28.4;small intestine: 56.2 gallbladder: 1.4 Cell line enriched 37 Hep G2: 6.3 +PREPL KIAA0436 ENSG00000138078 Prolyl endopeptidase-like 2 44316281-44361862 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA063238 Approved Expressed in all Expressed in all cerebral cortex: 257.4 Expressed in all +SLC3A1 ATR1, CSNU1, D2H, NBAT, RBAT ENSG00000138079 Solute carrier family 3 member 1 2 44275458-44321494 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA038360, HPA071102 Enhanced Approved Nuclear bodies
Mitochondria Renal cancer:3.67e-7 (favourable) Tissue enriched Tissue enhanced kidney: 688.2 small intestine: 148.9 Cell line enriched 14 RPTEC TERT1: 80.7 +EMILIN1 DKFZp586M121, gp115 ENSG00000138080 Elastin microfibril interfacer 1 2 27078567-27086408 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002822 Supported Renal cancer:8.13e-9 (unfavourable) Expressed in all Expressed in all seminal vesicle: 73.7 Cell line enhanced BJ: 81.8;HHSteC: 82.2;HSkMC: 78.7;SH-SY5Y: 135.3 +FBXO11 FBX11, UBR6 ENSG00000138081 F-box protein 11 2 47789316-47905793 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002690 Supported Nucleus Expressed in all Expressed in all testis: 75.4 Expressed in all +SIX3 HPE2 ENSG00000138083 SIX homeobox 3 2 44941898-44946077 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067988 Approved Nucleoplasm Mixed Tissue enriched 31 parathyroid gland: 39.3 cervix, uterine: 1.2 Cell line enhanced HAP1: 12.7;SCLC-21H: 77.1;SH-SY5Y: 27.8 +ATRAID APR3, C2orf28, HSPC013, p18 ENSG00000138085 All-trans retinoic acid induced differentiation factor 2 27212027-27217178 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051353 Uncertain Expressed in all Expressed in all epididymis: 521.0 Expressed in all +CENPO CENP-O, MGC11266 ENSG00000138092 Centromere protein O 2 24793136-24822376 Predicted intracellular proteins Evidence at protein level Renal cancer:5.71e-13 (unfavourable), Liver cancer:1.73e-6 (unfavourable), Endometrial cancer:3.54e-4 (unfavourable) Expressed in all Mixed testis: 13.0 Expressed in all +LRPPRC GP130, LRP130, LSFC ENSG00000138095 Leucine rich pentatricopeptide repeat containing 2 43886508-43996005 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB033786, HPA036408, HPA036409 Enhanced Enhanced Mitochondria Liver cancer:2.31e-7 (unfavourable), Renal cancer:6.65e-6 (favourable), Endometrial cancer:1.72e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 80.1 Expressed in all +TRIM54 MURF, MURF-3, RNF30 ENSG00000138100 Tripartite motif containing 54 2 27282392-27307439 Predicted intracellular proteins Evidence at protein level HPA019690 Uncertain Renal cancer:6.46e-4 (unfavourable) Mixed Tissue enhanced heart muscle: 63.9;skeletal muscle: 181.1 epididymis: 30.7 Group enriched 13 HAP1: 7.4;NTERA-2: 15.3 +DTNB ENSG00000138101 Dystrobrevin beta 2 25377198-25673647 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA061357 Uncertain Approved Mitochondria Liver cancer:2.54e-4 (unfavourable), Renal cancer:3.47e-4 (favourable) Expressed in all Mixed cerebral cortex: 23.8 Mixed +ACTR1A ARP1, Arp1A ENSG00000138107 ARP1 actin-related protein 1 homolog A, centractin alpha 10 102461881-102502711 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037193, HPA047443 Approved Approved Microtubules Expressed in all Expressed in all cerebral cortex: 114.3 Expressed in all +CYP2C9 CYP2C10, P450IIC9 ENSG00000138109 Cytochrome P450 family 2 subfamily C member 9 10 94938658-94989390 Enzymes, Predicted secreted proteins Evidence at protein level HPA015066, CAB016123 Enhanced Liver cancer:2.83e-6 (favourable) Tissue enriched Tissue enriched 7 liver: 963.1 duodenum: 136.8 Not detected +MFSD13A bA18I14.8, C10orf77, FLJ22529, TMEM180 ENSG00000138111 Major facilitator superfamily domain containing 13A 10 102461395-102477045 Predicted membrane proteins, Transporters Evidence at protein level HPA018031 Uncertain Approved Golgi apparatus
Cytosol Cervical cancer:8.29e-4 (favourable), Renal cancer:8.51e-4 (unfavourable) Expressed in all Mixed lung: 11.5 Mixed +CYP2C8 CPC8 ENSG00000138115 Cytochrome P450 family 2 subfamily C member 8 10 95036772-95069497 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA013547, HPA013970, HPA015066 Enhanced Pancreatic cancer:9.82e-4 (favourable) Tissue enriched Tissue enriched 154 liver: 1124.1 gallbladder: 7.3 Not detected +MYOF FER1L3, KIAA1207 ENSG00000138119 Myoferlin 10 93306429-93482317 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014245 Enhanced Supported Vesicles
Plasma membrane Pancreatic cancer:1.40e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 101.2 Mixed +LOXL4 FLJ21889, LOXC ENSG00000138131 Lysyl oxidase like 4 10 98247690-98268250 Predicted secreted proteins Evidence at protein level CAB033876, HPA037609 Approved Approved Vesicles Glioma:5.36e-4 (unfavourable), Ovarian cancer:9.57e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 17.8 Cell line enhanced BJ hTERT+: 199.7;CAPAN-2: 260.1;U-2 OS: 57.0 +STAMBPL1 ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, FLJ31524, KIAA1373 ENSG00000138134 STAM binding protein like 1 10 88879734-88975153 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040202 Uncertain Approved Plasma membrane Renal cancer:1.08e-5 (unfavourable) Mixed Mixed adrenal gland,testis: 29.7 Mixed +CH25H ENSG00000138135 Cholesterol 25-hydroxylase 10 89205629-89207314 Enzymes, Predicted membrane proteins Evidence at protein level Expressed in all Mixed gallbladder: 23.0 Cell line enhanced ASC diff: 6.0;fHDF/TERT166: 25.5;HSkMC: 6.0 +LBX1 HPX6, LBX1H ENSG00000138136 Ladybird homeobox 1 10 101226195-101229794 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA002016, HPA002086 Uncertain Approved Nucleoplasm
Nuclear bodies Not detected Tissue enriched 67 skeletal muscle: 9.1 lung: 0.1 Group enriched 8 HEK 293: 3.1;RH-30: 4.1;SCLC-21H: 10.7 +ATAD1 FLJ14600 ENSG00000138138 ATPase family, AAA domain containing 1 10 87751512-87841343 Enzymes, Predicted membrane proteins Evidence at protein level HPA037569 Uncertain Approved Nucleus
Nucleoli
Mitochondria Renal cancer:3.98e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 29.0 Expressed in all +BTBD16 C10orf87, Em:AC061711.1, FLJ25359 ENSG00000138152 BTB domain containing 16 10 122271306-122338162 Predicted intracellular proteins Evidence at protein level HPA040529, HPA057638 Uncertain Uncertain Nucleoli
Cytosol Renal cancer:1.50e-4 (unfavourable) Tissue enriched Group enriched 7 skin: 9.9;testis: 14.2;urinary bladder: 19.0 liver: 2.1 Cell line enriched 9 RT4: 26.9 +KIF11 Eg5, HKSP, KNSL1, TRIP5 ENSG00000138160 Kinesin family member 11 10 92593286-92655395 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006916, HPA010093, HPA010568, CAB017617 Enhanced Supported Mitotic spindle
Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:8.19e-7 (unfavourable), Pancreatic cancer:2.30e-4 (unfavourable), Lung cancer:3.27e-4 (unfavourable) Expressed in all Mixed testis: 21.8 Expressed in all +CUZD1 ERG-1, UO-44 ENSG00000138161 CUB and zona pellucida like domains 1 10 122832149-122850793 Predicted membrane proteins Evidence at protein level HPA068479, HPA068660, HPA074117 Enhanced Approved Nucleoli
Vesicles Tissue enriched Tissue enriched 173 pancreas: 380.6 testis: 2.1 Mixed +TACC2 AZU-1 ENSG00000138162 Transforming acidic coiled-coil containing protein 2 10 121989174-122254545 Predicted intracellular proteins Evidence at protein level HPA031020, HPA031021, HPA061394 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:2.50e-10 (favourable), Thyroid cancer:8.45e-4 (unfavourable) Expressed in all Mixed skeletal muscle: 112.7 Mixed +DUSP5 HVH3 ENSG00000138166 Dual specificity phosphatase 5 10 110497838-110511544 Enzymes, Predicted intracellular proteins Evidence at protein level Lung cancer:8.30e-6 (unfavourable) Expressed in all Mixed esophagus: 100.1 Cell line enhanced hTERT-HME1: 303.0;U-266/70: 167.5 +CALHM2 FAM26B ENSG00000138172 Calcium homeostasis modulator 2 10 103446786-103452402 Predicted membrane proteins, Transporters Evidence at protein level HPA014706 Approved Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:3.03e-6 (unfavourable) Expressed in all Mixed ovary: 44.8 Mixed +ARL3 ARFL3 ENSG00000138175 ADP ribosylation factor like GTPase 3 10 102673731-102714407 Predicted intracellular proteins Evidence at protein level HPA036292, HPA063596 Approved Supported Nucleus
Centrosome Renal cancer:1.71e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 35.8 Expressed in all +CEP55 C10orf3, CT111, FLJ10540 ENSG00000138180 Centrosomal protein 55 10 93496632-93529092 Predicted intracellular proteins Evidence at protein level HPA023430 Approved Supported Plasma membrane
Midbody
Microtubule organizing center Renal cancer:0.00e+0 (unfavourable), Liver cancer:3.20e-9 (unfavourable), Pancreatic cancer:2.66e-5 (unfavourable), Lung cancer:1.45e-4 (unfavourable), Stomach cancer:3.15e-4 (favourable) Expressed in all Tissue enhanced testis: 39.4 lymph node: 17.6 Mixed +KIF20B CT90, KRMP1, MPHOSPH1, MPP1 ENSG00000138182 Kinesin family member 20B 10 89701610-89774939 Predicted intracellular proteins Evidence at protein level HPA031263 Uncertain Renal cancer:3.06e-6 (unfavourable), Pancreatic cancer:1.21e-4 (unfavourable) Expressed in all Mixed testis: 12.8 Expressed in all +ENTPD1 ATPDase, CD39, NTPDase-1, SPG64 ENSG00000138185 Ectonucleoside triphosphate diphosphohydrolase 1 10 95711779-95869695 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB002494, HPA014067 Enhanced Uncertain Microtubules Renal cancer:5.33e-5 (unfavourable), Thyroid cancer:7.89e-4 (favourable) Expressed in all Mixed smooth muscle: 98.8 Group enriched 7 HDLM-2: 179.7;Karpas-707: 112.9 +EXOC6 DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, SEC15L, SEC15L1, Sec15p ENSG00000138190 Exocyst complex component 6 10 92834713-93059493 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA036285, HPA059111 Approved Supported Nucleoplasm
Vesicles Renal cancer:4.66e-4 (favourable) Expressed in all Expressed in all placenta: 49.7 Cell line enhanced HUVEC TERT2: 87.5 +PLCE1 KIAA1516, NPHS3, PLCE ENSG00000138193 Phospholipase C epsilon 1 10 94030812-94332823 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA015597, HPA015598 Enhanced Supported Cytosol Expressed in all Mixed endometrium: 21.6 Cell line enhanced RT4: 17.8;U-2 OS: 13.5 +RBP4 ENSG00000138207 Retinol binding protein 4 10 93591687-93601744 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001641, CAB004555 Supported Liver cancer:1.74e-8 (favourable), Endometrial cancer:1.50e-4 (unfavourable) Tissue enriched Tissue enriched 10 liver: 6109.2 adipose tissue: 630.9 Cell line enhanced CACO-2: 219.3;Hep G2: 755.1;PC-3: 113.0 +DBR1 ENSG00000138231 Debranching RNA lariats 1 3 138161012-138174949 Predicted intracellular proteins Evidence at protein level HPA035365 Supported Supported Nucleoplasm Liver cancer:1.36e-4 (unfavourable), Renal cancer:1.36e-4 (favourable) Expressed in all Expressed in all thyroid gland: 13.7 Expressed in all +DNAJC13 KIAA0678, RME8 ENSG00000138246 DnaJ heat shock protein family (Hsp40) member C13 3 132417526-132539032 Predicted membrane proteins Evidence at protein level HPA036923, HPA036924 Approved Supported Vesicles
Cytosol Liver cancer:7.49e-4 (unfavourable), Pancreatic cancer:8.36e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 28.9 Expressed in all +GPR87 GPR95 ENSG00000138271 G protein-coupled receptor 87 3 151294086-151316952 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA066313 Approved Nucleoplasm
Lipid droplets
Mitochondria Pancreatic cancer:4.62e-6 (unfavourable) Group enriched Tissue enhanced esophagus: 29.3;skin: 29.8 placenta: 12.0 Cell line enhanced A-431: 87.7;HaCaT: 68.9;HBEC3-KT: 74.5;hTCEpi: 98.3;hTERT-HME1: 43.6 +ANXA7 ANX7 ENSG00000138279 Annexin A7 10 73375101-73414076 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB004312, HPA064290 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.98e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 473.1 Expressed in all +FAM149B1 KIAA0974 ENSG00000138286 Family with sequence similarity 149 member B1 10 73168166-73244504 Predicted intracellular proteins Evidence at transcript level HPA039189, HPA039859 Uncertain Approved Nucleoplasm Pancreatic cancer:7.81e-4 (unfavourable) Expressed in all Expressed in all testis: 39.4 Expressed in all +ASCC1 ASC1p50, CGI-18, Em:AC022392.3 ENSG00000138303 Activating signal cointegrator 1 complex subunit 1 10 72096032-72217134 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038038, HPA057567 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:2.00e-4 (unfavourable), Liver cancer:3.52e-4 (unfavourable) Expressed in all Expressed in all testis: 45.7 Expressed in all +PLA2G12B PLA2G13 ENSG00000138308 Phospholipase A2 group XIIB 10 72935170-72954778 Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA057745, HPA059562 Approved Approved Vesicles Tissue enriched Group enriched 10 duodenum: 35.2;kidney: 19.0;liver: 49.9;small intestine: 45.9 lung: 3.9 Group enriched 6 CACO-2: 10.3;Hep G2: 14.2 +ZNF365 KIAA0844, UAN ENSG00000138311 Zinc finger protein 365 10 62374192-62672011 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA052446 Enhanced Supported Vesicles
Microtubule organizing center Mixed Tissue enhanced cerebral cortex: 54.5 parathyroid gland: 10.9 Cell line enhanced HaCaT: 18.7;PC-3: 12.7;U-251 MG: 14.7 +OIT3 FLJ39116, LZP ENSG00000138315 Oncoprotein induced transcript 3 10 72893581-72933033 Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 8 liver: 53.4 spleen: 6.5 Cell line enhanced CACO-2: 1.7;Hep G2: 1.5 +ADAMTS14 ENSG00000138316 ADAM metallopeptidase with thrombospondin type 1 motif 14 10 70672803-70762441 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA034605 Uncertain Cytosol Mixed Tissue enhanced gallbladder: 10.9;placenta: 11.1 urinary bladder: 4.4 Cell line enhanced CAPAN-2: 8.0;K-562: 9.5;RH-30: 5.3;U-138 MG: 8.8 +RPS24 S24 ENSG00000138326 Ribosomal protein S24 10 78033760-78056812 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003364 Approved Approved Nuclear bodies
Endoplasmic reticulum
Cytosol Renal cancer:1.10e-10 (unfavourable), Breast cancer:1.50e-4 (favourable) Expressed in all Expressed in all ovary: 6825.3 Expressed in all +TET1 bA119F7.1, CXXC6, KIAA1676, LCX ENSG00000138336 Tet methylcytosine dioxygenase 1 10 68560656-68694482 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019032, HPA057273 Supported Nucleus
Nuclear membrane Tissue enriched Mixed parathyroid gland: 2.4 Cell line enhanced BEWO: 17.6;HAP1: 21.7;K-562: 11.0;NTERA-2: 12.2 +DNA2 DNA2L, KIAA0083 ENSG00000138346 DNA replication helicase/nuclease 2 10 68414064-68472121 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037487, HPA057526 Approved Supported Mitochondria Mixed Mixed lymph node: 6.3 Mixed +MYPN MYOP ENSG00000138347 Myopalladin 10 68106117-68212017 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036299, HPA061494 Enhanced Approved Nucleus
Vesicles
Cytosol Tissue enriched Group enriched 27 heart muscle: 41.6;skeletal muscle: 99.9 prostate: 2.6 Cell line enhanced BJ: 33.6;fHDF/TERT166: 87.0;HBF TERT88: 24.6;LHCN-M2: 39.6 +AOX1 AO, AOH1 ENSG00000138356 Aldehyde oxidase 1 2 200585868-200677064 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040199, HPA040215 Enhanced Renal cancer:6.05e-5 (favourable) Tissue enriched Group enriched 5 adrenal gland: 368.8;kidney: 97.5;liver: 432.3 ovary: 56.8 Cell line enhanced ASC diff: 241.4;ASC TERT1: 125.7;hTERT-HME1: 56.6 +ATIC AICARFT, IMPCHASE, PURH ENSG00000138363 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2 215311817-215349773 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013462, HPA021012 Supported Enhanced Plasma membrane
Cytosol Liver cancer:1.99e-7 (unfavourable), Renal cancer:8.77e-4 (unfavourable) Expressed in all Expressed in all placenta: 44.8 Expressed in all +SMARCAL1 HARP, HHARP ENSG00000138375 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 2 216412414-216483053 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020337 Uncertain Supported Nucleoplasm Liver cancer:5.22e-4 (unfavourable) Expressed in all Expressed in all ovary: 19.8 Expressed in all +BARD1 ENSG00000138376 BRCA1 associated RING domain 1 2 214725646-214809711 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034106, HPA035354, HPA044864 Enhanced Supported Nuclear speckles Expressed in all Mixed testis: 11.1 Mixed +STAT4 ENSG00000138378 Signal transducer and activator of transcription 4 2 191029576-191151596 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001860, CAB013108 Enhanced Renal cancer:1.07e-8 (unfavourable), Pancreatic cancer:5.88e-4 (favourable) Mixed Tissue enhanced testis: 50.5 spleen: 18.5 Group enriched 7 Karpas-707: 34.1;U-266/70: 20.1;U-266/84: 6.9 +MSTN GDF8 ENSG00000138379 Myostatin 2 190055697-190062729 Disease related genes, Predicted secreted proteins Evidence at protein level CAB009963 Approved Glioma:3.98e-4 (favourable) Tissue enriched Tissue enhanced skeletal muscle: 3.4 cerebral cortex,endometrium: 1.3 Group enriched 13 LHCN-M2: 21.5;RH-30: 50.3 +CARF ALS2CR8, CaRF, FLJ21579, NYD-SP24 ENSG00000138380 Calcium responsive transcription factor 2 202912214-202987063 Predicted intracellular proteins Evidence at protein level HPA034557, HPA043191 Approved Approved Nucleoli fibrillar center
Vesicles
Cytosol Mixed Mixed testis: 37.0 Expressed in all +ASNSD1 FLJ20752, NBLA00058, NS3TP1 ENSG00000138381 Asparagine synthetase domain containing 1 2 189661385-189670831 Predicted intracellular proteins Evidence at protein level HPA036132, HPA036133, HPA075042 Uncertain Approved Cytosol Glioma:5.68e-4 (favourable), Liver cancer:8.66e-4 (unfavourable) Expressed in all Expressed in all placenta: 51.4 Expressed in all +METTL5 HSPC133 ENSG00000138382 Methyltransferase like 5 2 169810081-169824931 Predicted intracellular proteins Evidence at protein level HPA038223 Uncertain Approved Nucleoli
Cytosol Renal cancer:3.06e-8 (unfavourable), Liver cancer:6.64e-5 (unfavourable) Expressed in all Expressed in all epididymis: 76.8 Expressed in all +SSB La, La/SSB, LARP3 ENSG00000138385 Sjogren syndrome antigen B 2 169791933-169812064 Predicted intracellular proteins Evidence at protein level CAB004643, HPA017287 Supported Approved Nucleoplasm Liver cancer:8.30e-8 (unfavourable), Renal cancer:6.17e-6 (unfavourable), Head and neck cancer:5.99e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 131.2 Expressed in all +NAB1 ENSG00000138386 NGFI-A binding protein 1 2 190646746-190692766 Predicted intracellular proteins Evidence at protein level HPA002738 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Pancreatic cancer:1.01e-4 (unfavourable) Expressed in all Expressed in all skin: 80.6 Expressed in all +CDK15 ALS2CR7, PFTAIRE2, PFTK2 ENSG00000138395 Cyclin dependent kinase 15 2 201790461-201895550 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015786 Uncertain Approved Nucleus
Golgi apparatus Not detected Tissue enhanced epididymis: 21.2;ovary: 8.4 testis: 4.0 Cell line enhanced BJ hTERT+: 23.4;BJ hTERT+ SV40 Large T+ RasG12V: 22.4;HBF TERT88: 33.8;HMC-1: 58.6;LHCN-M2: 16.8 +PPIG CARS-Cyp, SCAF10, SRCyp ENSG00000138398 Peptidylprolyl isomerase G 2 169584340-169641406 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021788, HPA057469 Supported Supported Nuclear speckles
Cytosol Renal cancer:4.56e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 84.6 Expressed in all +FASTKD1 FLJ21901 ENSG00000138399 FAST kinase domains 1 2 169529749-169573875 Predicted intracellular proteins Evidence at protein level HPA043719 Approved Approved Nucleoplasm Expressed in all Expressed in all rectum: 26.5 Expressed in all +MDH1B FLJ25341, RP11-95H11 ENSG00000138400 Malate dehydrogenase 1B 2 206737763-206765547 Predicted intracellular proteins Evidence at transcript level HPA073761 Approved Mixed Group enriched 5 fallopian tube: 35.3;testis: 43.8 parathyroid gland: 7.5 Cell line enhanced SCLC-21H: 4.0 +HECW2 KIAA1301, NEDL2 ENSG00000138411 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 2 196194370-196593692 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA034609 Uncertain Approved Nucleoli fibrillar center
Endoplasmic reticulum Renal cancer:5.18e-5 (unfavourable) Mixed Mixed placenta: 15.8 Cell line enhanced HDLM-2: 59.6;HUVEC TERT2: 24.5;SCLC-21H: 45.1;TIME: 32.0 +IDH1 ENSG00000138413 Isocitrate dehydrogenase (NADP(+)) 1, cytosolic 2 208236227-208266074 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033218, HPA035248, HPA057936, CAB062556 Enhanced Approved Nuclear bodies
Cytosol Renal cancer:2.45e-5 (unfavourable), Liver cancer:6.93e-5 (unfavourable) Expressed in all Expressed in all prostate: 338.1 Expressed in all +OLA1 GTPBP9, PTD004 ENSG00000138430 Obg like ATPase 1 2 174072447-174248698 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035790, HPA041443 Approved Enhanced Cytosol Liver cancer:9.73e-8 (unfavourable) Expressed in all Expressed in all thyroid gland: 99.7 Expressed in all +CIR1 CIR ENSG00000138433 Corepressor interacting with RBPJ, 1 2 174348022-174395715 Predicted intracellular proteins Evidence at protein level HPA015784, HPA061442 Approved Supported Nuclear speckles Renal cancer:1.04e-7 (unfavourable), Urothelial cancer:2.04e-5 (favourable), Liver cancer:2.52e-4 (unfavourable), Endometrial cancer:9.56e-4 (unfavourable), Ovarian cancer:9.80e-4 (favourable) Expressed in all Expressed in all testis: 57.1 Expressed in all +SSFA2 CS-1, KIAA1927, KRAP, SPAG13 ENSG00000138434 Sperm specific antigen 2 2 181891833-181930738 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034665, HPA039989 Uncertain Supported Nucleus
Plasma membrane
Cytosol Renal cancer:2.91e-5 (favourable), Urothelial cancer:5.79e-5 (unfavourable), Pancreatic cancer:8.19e-4 (unfavourable) Expressed in all Expressed in all skin: 137.2 Mixed +CHRNA1 CHRNA ENSG00000138435 Cholinergic receptor nicotinic alpha 1 subunit 2 174747592-174787935 Disease related genes, Predicted membrane proteins, Transporters Evidence at protein level HPA071554 Enhanced Supported Plasma membrane Tissue enhanced Tissue enhanced prostate: 3.2;skeletal muscle: 7.2 colon: 1.5 Group enriched 23 LHCN-M2: 370.9;RH-30: 348.5 +FAM117B ALS2CR13, FLJ38771 ENSG00000138439 Family with sequence similarity 117 member B 2 202635188-202769757 Predicted intracellular proteins Evidence at protein level HPA003229, HPA028746 Uncertain Approved Nucleus
Centrosome Expressed in all Mixed parathyroid gland: 24.4 Mixed +WDR12 FLJ10881, YTM1 ENSG00000138442 WD repeat domain 12 2 202874782-203014798 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036389 Uncertain Approved Nucleoli
Plasma membrane
Cytosol Liver cancer:2.57e-6 (unfavourable) Expressed in all Mixed testis: 7.3 Expressed in all +ABI2 ABI-2, ABI2B, AblBP3, AIP-1, argBPIA, SSH3BP2 ENSG00000138443 Abl interactor 2 2 203328219-203447723 Predicted intracellular proteins Evidence at protein level HPA062433, HPA070567 Enhanced Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 98.8 Mixed +ITGAV CD51, MSK8, VNRA, VTNR ENSG00000138448 Integrin subunit alpha V 2 186590065-186680901 Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB002499, HPA004856 Supported Approved Focal adhesion sites
Cytosol Stomach cancer:1.05e-6 (unfavourable), Liver cancer:2.08e-4 (unfavourable), Pancreatic cancer:5.07e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 191.2 Cell line enhanced RT4: 294.1 +SLC40A1 FPN1, HFE4, IREG1, MTP1, SLC11A3 ENSG00000138449 Solute carrier family 40 member 1 2 189560579-189583758 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA065634 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:8.55e-5 (favourable) Expressed in all Expressed in all spleen: 489.1 Group enriched 6 ASC diff: 336.9;CACO-2: 97.8;HEL: 380.0;HMC-1: 94.0;T-47d: 188.1 +SLC35A5 FLJ20730 ENSG00000138459 Solute carrier family 35 member A5 3 112561709-112585577 Predicted membrane proteins, Transporters Evidence at protein level HPA035519, HPA057964 Uncertain Approved Golgi apparatus Renal cancer:4.10e-5 (favourable) Expressed in all Expressed in all thyroid gland: 43.9 Expressed in all +DIRC2 FLJ14784, RCC4 ENSG00000138463 Disrupted in renal carcinoma 2 3 122794795-122881139 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA072579 Supported Vesicles Renal cancer:8.81e-11 (favourable), Pancreatic cancer:5.81e-5 (unfavourable), Liver cancer:7.48e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 16.2 Mixed +SENP7 ENSG00000138468 SUMO1/sentrin specific peptidase 7 3 101324205-101513241 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027259 Approved Approved Nucleoplasm
Cytosol Head and neck cancer:4.23e-4 (favourable) Expressed in all Expressed in all endometrium: 44.4 Expressed in all +GUCA1C GCAP3 ENSG00000138472 Guanylate cyclase activator 1C 3 108907792-108953895 Predicted intracellular proteins Evidence at protein level HPA041597 Approved Approved Focal adhesion sites Tissue enriched Tissue enhanced heart muscle: 8.9;pancreas: 8.4;stomach: 5.3 testis: 1.7 Cell line enriched 83 RPTEC TERT1: 10.6 +CCDC54 FLJ25362, NYD-SP17, SP17 ENSG00000138483 Coiled-coil domain containing 54 3 107377194-107378637 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 137 testis: 165.4 placenta: 1.2 Not detected +COX17 ENSG00000138495 COX17, cytochrome c oxidase copper chaperone 3 119654513-119677454 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA042226, HPA048158 Supported Supported Mitochondria Expressed in all Expressed in all adrenal gland: 114.8 Expressed in all +PARP9 BAL, BAL1 ENSG00000138496 Poly(ADP-ribose) polymerase family member 9 3 122527924-122564577 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA066708 Supported Nucleoplasm
Mitochondria
Cytosol Ovarian cancer:6.65e-4 (favourable) Expressed in all Expressed in all spleen: 60.9 Cell line enhanced BJ hTERT+ SV40 Large T+: 89.2;BJ hTERT+ SV40 Large T+ RasG12V: 110.6 +MNS1 FLJ11222, SPATA40 ENSG00000138587 Meiosis specific nuclear structural 1 15 56421544-56465137 Predicted intracellular proteins Evidence at protein level HPA039975, HPA040382 Uncertain Approved Nucleoplasm
Nuclear speckles Expressed in all Group enriched 6 fallopian tube: 33.7;testis: 86.9 kidney: 9.7 Mixed +USP8 HumORF8, KIAA0055, SPG59, UBPY ENSG00000138592 Ubiquitin specific peptidase 8 15 50424380-50514419 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA050215 Approved Supported Golgi apparatus
Cytosol Renal cancer:1.29e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 77.0 Expressed in all +SECISBP2L KIAA0256 ENSG00000138593 SECIS binding protein 2 like 15 48988476-49046563 Predicted intracellular proteins Evidence at protein level HPA039875 Approved Approved Nucleoplasm Renal cancer:5.65e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 84.6 Expressed in all +TMOD3 UTMOD ENSG00000138594 Tropomodulin 3 15 51829628-51947295 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001849 Approved Approved Actin filaments
Cytosol Pancreatic cancer:3.38e-5 (unfavourable), Cervical cancer:3.25e-4 (unfavourable), Lung cancer:6.25e-4 (unfavourable) Expressed in all Expressed in all esophagus: 47.7 Expressed in all +SPPL2A IMP3, PSL2 ENSG00000138600 Signal peptide peptidase like 2A 15 50702266-50765808 Enzymes, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA036062, HPA067304 Enhanced Supported Vesicles Expressed in all Expressed in all parathyroid gland: 291.5 Expressed in all +GLCE HSEPI, KIAA0836 ENSG00000138604 Glucuronic acid epimerase 15 69160584-69272217 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040481, HPA048216 Uncertain Approved Mitochondria Expressed in all Mixed placenta: 19.1 Cell line enhanced HUVEC TERT2: 99.7 +SHF ENSG00000138606 Src homology 2 domain containing F 15 45167214-45201175 Predicted intracellular proteins Evidence at protein level HPA057381 Approved Nucleus Expressed in all Mixed adrenal gland: 29.9 Cell line enhanced SCLC-21H: 142.5;SH-SY5Y: 57.3 +APH1B APH-1B, DKFZp564D0372, PSFL ENSG00000138613 Aph-1 homolog B, gamma-secretase subunit 15 63276018-63309126 Predicted membrane proteins Evidence at protein level Pancreatic cancer:1.05e-4 (favourable), Renal cancer:2.25e-4 (favourable) Expressed in all Tissue enhanced testis: 153.4 thyroid gland: 32.1 Mixed +INTS14 C15orf44, DKFZP564O1664, VWA9 ENSG00000138614 Integrator complex subunit 14 15 65578753-65611289 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040255, HPA040651 Approved Approved Nucleoplasm
Nuclear membrane
Nuclear bodies
Mitochondria Expressed in all Expressed in all fallopian tube: 39.1 Expressed in all +CILP HsT18872 ENSG00000138615 Cartilage intermediate layer protein 15 65194758-65211488 Disease related genes, Predicted secreted proteins Evidence at protein level HPA003195 Uncertain Thyroid cancer:2.24e-5 (unfavourable) Tissue enhanced Tissue enhanced cervix, uterine: 67.0;smooth muscle: 70.8 gallbladder: 54.9 Cell line enhanced ASC diff: 2.9;ASC TERT1: 1.7;EFO-21: 1.0;HSkMC: 4.7 +PARP16 C15orf30, FLJ20509, FLJ25281, pART15 ENSG00000138617 Poly(ADP-ribose) polymerase family member 16 15 65234460-65300618 Enzymes, Predicted membrane proteins Evidence at protein level HPA017081 Approved Expressed in all Expressed in all ovary: 13.0 Expressed in all +PPCDC FLJ14585, MDS018 ENSG00000138621 Phosphopantothenoylcysteine decarboxylase 15 75023555-75117462 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045667 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 22.4 Expressed in all +HCN4 ENSG00000138622 Hyperpolarization activated cyclic nucleotide gated potassium channel 4 15 73319859-73369264 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Group enriched Group enriched 6 cerebral cortex: 1.4;heart muscle: 1.5;testis: 6.7 adrenal gland: 0.5 Cell line enhanced AF22: 1.2;CACO-2: 1.3;NTERA-2: 4.7;U-2 OS: 2.1 +SEMA7A CD108, H-Sema-L, SEMAL ENSG00000138623 Semaphorin 7A (John Milton Hagen blood group) 15 74409289-74434467 Blood group antigen proteins, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008210, HPA042273 Uncertain Uncertain Vesicles Renal cancer:2.45e-11 (unfavourable) Expressed in all Tissue enhanced spleen: 59.6;testis: 56.9 placenta: 44.8 Cell line enhanced HMC-1: 510.6;hTEC/SVTERT24-B: 213.0;U-251 MG: 310.7 +UBL7 BMSC-UbP, MGC14421 ENSG00000138629 Ubiquitin like 7 15 74445977-74461182 Predicted intracellular proteins Evidence at protein level HPA040423, HPA041897 Approved Approved Nucleoplasm
Cytosol Cervical cancer:6.37e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 76.4 Expressed in all +ARHGAP24 DKFZP564B1162, FilGAP, FLJ33877 ENSG00000138639 Rho GTPase activating protein 24 4 85475114-86002670 Predicted intracellular proteins Evidence at protein level HPA014288 Approved Approved Plasma membrane
Cytosol Renal cancer:1.67e-11 (favourable) Expressed in all Expressed in all kidney: 106.3 Cell line enhanced ASC diff: 75.0;HUVEC TERT2: 101.5;TIME: 70.7 +FAM13A ARHGAP48, FAM13A1, KIAA0914 ENSG00000138640 Family with sequence similarity 13 member A 4 88725955-89111398 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038108, HPA038109 Uncertain Approved Nucleoli
Cell Junctions
Cytosol Urothelial cancer:4.28e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 114.4 Cell line enhanced ASC diff: 38.0 +HERC3 KIAA0032 ENSG00000138641 HECT and RLD domain containing E3 ubiquitin protein ligase 3 4 88521048-88708542 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039170 Approved Approved Cytosol Renal cancer:5.65e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 61.0 Mixed +HERC6 FLJ20637 ENSG00000138642 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4 88378739-88443111 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035846 Uncertain Approved Nucleus
Cytosol Renal cancer:7.14e-5 (favourable) Expressed in all Expressed in all esophagus: 22.8 Group enriched 5 BJ hTERT+ SV40 Large T+: 108.0;BJ hTERT+ SV40 Large T+ RasG12V: 83.5 +HERC5 CEB1 ENSG00000138646 HECT and RLD domain containing E3 ubiquitin protein ligase 5 4 88457117-88506163 Predicted membrane proteins Evidence at protein level HPA043929 Supported Endometrial cancer:4.46e-5 (unfavourable) Expressed in all Tissue enhanced testis: 106.5 endometrium: 25.6 Cell line enhanced BJ hTERT+ SV40 Large T+: 83.8;BJ hTERT+ SV40 Large T+ RasG12V: 120.3 +PCDH10 KIAA1400, OL-PCDH ENSG00000138650 Protocadherin 10 4 133149315-133208606 Predicted membrane proteins Evidence at protein level HPA011220, HPA073462 Approved Approved Nucleus
Golgi apparatus
Vesicles Tissue enhanced Group enriched 5 cerebral cortex: 62.0;placenta: 36.7;prostate: 17.6;seminal vesicle: 24.5 adrenal gland: 6.8 Cell line enhanced HUVEC TERT2: 23.1;MOLT-4: 19.4;TIME: 45.4;U-138 MG: 14.3 +NDST4 ENSG00000138653 N-deacetylase and N-sulfotransferase 4 4 114827763-115113876 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011129 Uncertain Not detected Tissue enhanced cerebral cortex: 1.4;ovary: 1.8 spleen: 1.0 Cell line enhanced AF22: 2.8;CACO-2: 2.4;RH-30: 14.2;T-47d: 3.1 +ZGRF1 C4orf21, FLJ11331 ENSG00000138658 Zinc finger GRF-type containing 1 4 112539333-112636995 Predicted intracellular proteins Evidence at protein level HPA030704, HPA030706 Uncertain Approved Cytosol Mixed Mixed testis: 6.7 Mixed +AP1AR 2C18, C4orf16, gamma-BAR, PRO0971 ENSG00000138660 Adaptor related protein complex 1 associated regulatory protein 4 112231737-112270047 Predicted intracellular proteins Evidence at protein level HPA035863, HPA058115 Approved Supported Golgi apparatus Renal cancer:4.05e-7 (favourable), Urothelial cancer:7.79e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 57.7 Expressed in all +COPS4 CSN4 ENSG00000138663 COP9 signalosome subunit 4 4 83034447-83075818 Predicted intracellular proteins Evidence at protein level HPA036894, HPA042828 Uncertain Supported Nuclear speckles Renal cancer:5.21e-6 (favourable), Colorectal cancer:4.14e-4 (favourable) Expressed in all Expressed in all testis: 79.0 Expressed in all +HNRNPD AUF1, HNRPD ENSG00000138668 Heterogeneous nuclear ribonucleoprotein D 4 82352498-82374503 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004911 Supported Enhanced Nucleoplasm Expressed in all Expressed in all lymph node: 341.0 Expressed in all +PRKG2 cGKII, PRKGR2 ENSG00000138669 Protein kinase, cGMP-dependent, type II 4 81087370-81215117 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007386, CAB018739 Approved Tissue enhanced Tissue enhanced prostate: 15.3;small intestine: 14.4 duodenum: 9.7 Cell line enhanced HEL: 18.8;SCLC-21H: 7.3 +RASGEF1B FLJ31695, GPIG4 ENSG00000138670 RasGEF domain family member 1B 4 81426393-82044244 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA044574 Uncertain Approved Nucleoplasm
Vesicles Renal cancer:4.21e-6 (favourable), Head and neck cancer:1.49e-5 (favourable), Cervical cancer:6.40e-4 (favourable) Expressed in all Mixed skin: 31.6 Cell line enhanced CACO-2: 12.9;Daudi: 13.1;Karpas-707: 9.0;NTERA-2: 11.1;SCLC-21H: 10.7 +SEC31A ABP125, ABP130, KIAA0905, SEC31L1 ENSG00000138674 SEC31 homolog A, COPII coat complex component 4 82818661-82901166 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA005457 Approved Supported Vesicles
Cytosol Urothelial cancer:2.69e-4 (unfavourable), Liver cancer:3.32e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 281.0 Expressed in all +FGF5 ENSG00000138675 Fibroblast growth factor 5 4 80266599-80336680 Disease related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB010313, HPA042442 Supported Nucleus
Nucleoli fibrillar center
Cytosol Not detected Tissue enhanced gallbladder: 5.6 smooth muscle: 1.4 Cell line enhanced BJ hTERT+: 97.8;fHDF/TERT166: 68.3;HBF TERT88: 85.6;LHCN-M2: 67.6;U-138 MG: 108.3 +GPAT3 AGPAT10, AGPAT9, HMFN0839, LPAAT-theta, MAG1, MGC11324 ENSG00000138678 Glycerol-3-phosphate acyltransferase 3 4 83535914-83605875 Enzymes, Predicted membrane proteins Evidence at protein level HPA029414, CAB033749 Approved Uncertain Plasma membrane
Cytosol Renal cancer:2.71e-9 (favourable), Urothelial cancer:8.21e-4 (unfavourable) Mixed Tissue enhanced kidney: 89.9 duodenum: 40.7 Cell line enhanced CAPAN-2: 141.3;U-87 MG: 67.1;WM-115: 52.9 +IL21 IL-21, Za11 ENSG00000138684 Interleukin 21 4 122612628-122621069 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enhanced lymph node: 18.1;tonsil: 6.3 testis: 4.1 Not detected +FGF2 FGFB ENSG00000138685 Fibroblast growth factor 2 4 122826708-122898236 Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB000125 Approved Supported Nucleoplasm
Nuclear bodies Pancreatic cancer:9.85e-4 (unfavourable) Mixed Mixed adipose tissue: 26.1 Cell line enhanced BJ: 206.0;fHDF/TERT166: 215.4 +BBS7 BBS2L1, FLJ10715 ENSG00000138686 Bardet-Biedl syndrome 7 4 121824440-121870497 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044592 Approved Expressed in all Mixed cerebral cortex: 25.7 Expressed in all +KIAA1109 FLJ21404, FSA, KIAA1371, Tweek ENSG00000138688 KIAA1109 4 122152333-122362758 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038076 Approved Approved Nucleoplasm
Centrosome Renal cancer:4.33e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 130.9 Expressed in all +BMPR1B ALK6, CDw293 ENSG00000138696 Bone morphogenetic protein receptor type 1B 4 94757968-95158448 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Endometrial cancer:2.84e-4 (favourable) Tissue enhanced Tissue enhanced cervix, uterine: 37.2;prostate: 37.0 seminal vesicle: 21.0 Cell line enhanced A549: 21.1;SH-SY5Y: 20.1 +RAP1GDS1 SmgGDS ENSG00000138698 Rap1 GTPase-GDP dissociation stimulator 1 4 98261384-98443861 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA019060 Approved Supported Cytosol Renal cancer:2.00e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 93.9 Expressed in all +LARP1B DKFZp434K245, DKFZp686E0316, FLJ10378, LARP2 ENSG00000138709 La ribonucleoprotein domain family member 1B 4 128061268-128222931 Predicted intracellular proteins Evidence at protein level HPA036280 Approved Approved Cytosol Renal cancer:5.13e-5 (favourable) Expressed in all Expressed in all testis: 103.0 Expressed in all +MMRN1 ECM, EMILIN4, GPIa*, MMRN ENSG00000138722 Multimerin 1 4 89879532-89954629 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035769 Enhanced Approved Endoplasmic reticulum Renal cancer:1.77e-4 (unfavourable), Stomach cancer:5.46e-4 (unfavourable) Mixed Mixed placenta: 57.5 Cell line enriched 11 HUVEC TERT2: 1035.6 +PDE5A ENSG00000138735 Phosphodiesterase 5A 4 119494395-119628991 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA004729, HPA012873 Approved Approved Cytosol Urothelial cancer:1.17e-4 (unfavourable), Cervical cancer:5.20e-4 (favourable) Expressed in all Mixed prostate: 97.7 Cell line enhanced BJ hTERT+: 38.5;HHSteC: 55.3 +PRDM5 PFM2 ENSG00000138738 PR/SET domain 5 4 120684919-120922870 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051406 Enhanced Supported Nucleus
Nucleoli
Nuclear bodies Mixed Mixed parathyroid gland: 20.7 Mixed +TRPC3 ENSG00000138741 Transient receptor potential cation channel subfamily C member 3 4 121879027-121951754 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA037969 Uncertain Not detected Tissue enhanced smooth muscle: 4.1 cerebral cortex: 2.1 Cell line enhanced HEK 293: 1.6;HEL: 2.4;Karpas-707: 1.9;U-2 OS: 1.8 +NAAA ASAHL ENSG00000138744 N-acylethanolamine acid amidase 4 75913657-75941051 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026135 Approved Endometrial cancer:1.93e-4 (favourable), Pancreatic cancer:4.90e-4 (favourable) Expressed in all Expressed in all prostate: 114.9 Mixed +NUP54 ENSG00000138750 Nucleoporin 54 4 76114659-76148515 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA035929, HPA058122 Approved Approved Nucleoplasm Liver cancer:4.64e-4 (unfavourable), Colorectal cancer:8.80e-4 (favourable) Expressed in all Expressed in all testis: 39.1 Expressed in all +CXCL9 CMK, crg-10, Humig, MIG, SCYB9 ENSG00000138755 C-X-C motif chemokine ligand 9 4 76001275-76007488 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:5.15e-6 (unfavourable), Endometrial cancer:2.07e-4 (favourable), Breast cancer:6.36e-4 (favourable), Ovarian cancer:8.06e-4 (favourable) Expressed in all Tissue enhanced lymph node: 327.4 appendix: 86.2 Not detected +BMP2K BIKe, DKFZp434K0614 ENSG00000138756 BMP2 inducible kinase 4 78776342-78916372 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026436, HPA026451, HPA026501 Approved Supported Nuclear speckles Colorectal cancer:1.74e-4 (favourable) Mixed Mixed testis: 32.8 Expressed in all +G3BP2 KIAA0660 ENSG00000138757 G3BP stress granule assembly factor 2 4 75642782-75724525 Predicted intracellular proteins Evidence at protein level HPA018304, HPA018425 Enhanced Enhanced Cytosol Renal cancer:6.65e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 178.5 Expressed in all +SEPT11 FLJ10849 ENSG00000138758 Septin 11 4 76949703-77040384 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003459, HPA005665 Approved Approved Cytosol Liver cancer:1.70e-5 (unfavourable), Renal cancer:2.40e-4 (favourable) Expressed in all Expressed in all placenta: 120.1 Mixed +FRAS1 FLJ14927, FLJ22031, KIAA1500 ENSG00000138759 Fraser extracellular matrix complex subunit 1 4 78057570-78544269 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011281, HPA051601 Approved Approved Nucleoli fibrillar center Renal cancer:4.69e-4 (favourable) Mixed Tissue enhanced thyroid gland: 20.2 kidney,placenta: 8.2 Cell line enhanced fHDF/TERT166: 28.1;RH-30: 19.7;SiHa: 23.0 +SCARB2 CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII ENSG00000138760 Scavenger receptor class B member 2 4 76158733-76234536 Disease related genes, Predicted membrane proteins Evidence at protein level CAB015415, HPA018014 Supported Approved Cytosol Breast cancer:2.82e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 112.1 Mixed +CCNG2 ENSG00000138764 Cyclin G2 4 77157151-77433388 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level HPA034684 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.47e-5 (favourable), Pancreatic cancer:8.57e-4 (unfavourable) Expressed in all Expressed in all esophagus: 150.2 Expressed in all +CNOT6L Ccr4b, DKFZp434K098 ENSG00000138767 CCR4-NOT transcription complex subunit 6 like 4 77713387-77819615 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042688 Uncertain Supported Cytosol Renal cancer:1.69e-4 (favourable) Expressed in all Expressed in all lymph node: 43.7 Expressed in all +USO1 p115, TAP, VDP ENSG00000138768 USO1 vesicle transport factor 4 75724593-75814286 Predicted intracellular proteins Evidence at protein level CAB010108, HPA038282, HPA038283 Supported Enhanced Nucleoli fibrillar center
Golgi apparatus Expressed in all Expressed in all thyroid gland: 91.1 Expressed in all +CDKL2 KKIAMRE, P56 ENSG00000138769 Cyclin dependent kinase like 2 4 75578005-75630716 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040672 Approved Nucleus
Centrosome Renal cancer:6.88e-15 (favourable) Mixed Tissue enhanced testis: 33.1 cerebral cortex: 9.8 Cell line enhanced A-431: 2.7;RPTEC TERT1: 3.3 +SHROOM3 APXL3, KIAA1481, SHRM, ShrmL ENSG00000138771 Shroom family member 3 4 76435100-76783253 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047784 Enhanced Renal cancer:1.64e-13 (favourable) Expressed in all Mixed parathyroid gland: 27.6 Cell line enhanced AF22: 30.8 +ANXA3 ANX3 ENSG00000138772 Annexin A3 4 78551519-78610451 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013398, HPA013431 Enhanced Supported Cytosol Renal cancer:8.48e-6 (favourable), Pancreatic cancer:1.28e-4 (unfavourable) Mixed Expressed in all bone marrow: 198.3 Cell line enhanced A-431: 316.4;CACO-2: 302.6;CAPAN-2: 428.5;EFO-21: 275.3;hTERT-HME1: 372.7;RPTEC TERT1: 312.0 +PPA2 FLJ20459 ENSG00000138777 Pyrophosphatase (inorganic) 2 4 105369077-105474081 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA030888, HPA031671, HPA031672 Supported Approved Nucleus
Mitochondria Renal cancer:1.27e-11 (favourable), Breast cancer:2.98e-4 (unfavourable), Colorectal cancer:6.60e-4 (favourable) Expressed in all Expressed in all prostate: 21.3 Expressed in all +CENPE KIF10, PPP1R61 ENSG00000138778 Centromere protein E 4 103105806-103198409 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042294 Approved Approved Nucleoplasm
Microtubules
Cytosol Mixed Mixed testis: 7.7 Mixed +GSTCD FLJ13273 ENSG00000138780 Glutathione S-transferase C-terminal domain containing 4 105708778-105847728 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046160, HPA061782 Approved Supported Nucleus Expressed in all Mixed testis: 19.5 Expressed in all +INTS12 INT12, PHF22, SBBI22 ENSG00000138785 Integrator complex subunit 12 4 105682627-105895986 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA035772, HPA041814 Approved Approved Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Liver cancer:2.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 33.5 Expressed in all +ENPEP CD249, gp160 ENSG00000138792 Glutamyl aminopeptidase 4 110365733-110565285 CD markers, Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA002821, HPA005128 Enhanced Approved Endoplasmic reticulum Tissue enriched Group enriched 5 duodenum: 36.5;kidney: 94.3;parathyroid gland: 160.7;small intestine: 180.3 placenta: 21.5 Cell line enhanced BEWO: 2.6;HEK 293: 6.8;MOLT-4: 1.4 +CASP6 MCH2 ENSG00000138794 Caspase 6 4 109688622-109703583 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB003775, HPA011337, HPA024303 Enhanced Supported Nucleus
Cytosol Colorectal cancer:2.64e-5 (favourable), Urothelial cancer:9.93e-4 (favourable) Expressed in all Expressed in all small intestine: 46.1 Expressed in all +LEF1 TCF10, TCF1ALPHA, TCF7L3 ENSG00000138795 Lymphoid enhancer binding factor 1 4 108047545-108168956 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002087, CAB019405 Enhanced Approved Nucleoplasm Renal cancer:2.47e-6 (unfavourable), Endometrial cancer:1.37e-5 (favourable) Expressed in all Tissue enhanced lymph node: 41.7 tonsil: 28.3 Group enriched 6 MOLT-4: 512.4;REH: 443.8 +HADH HADH1, HADHSC, SCHAD ENSG00000138796 Hydroxyacyl-CoA dehydrogenase 4 107989714-108035175 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039588, HPA043888 Supported Supported Mitochondria Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all adipose tissue: 154.5 Expressed in all +EGF ENSG00000138798 Epidermal growth factor 4 109912884-110012266 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Mixed Tissue enriched 7 kidney: 122.1 pancreas: 18.5 Cell line enhanced EFO-21: 5.9;SK-BR-3: 8.5;U-251 MG: 3.0 +PAPSS1 ATPSK1, PAPSS ENSG00000138801 3'-phosphoadenosine 5'-phosphosulfate synthase 1 4 107590276-107720452 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049781 Approved Approved Nucleus
Nucleoli Liver cancer:2.70e-5 (unfavourable), Endometrial cancer:8.58e-4 (favourable), Colorectal cancer:9.14e-4 (favourable) Expressed in all Expressed in all endometrium: 73.7 Expressed in all +SEC24B ENSG00000138802 SEC24 homolog B, COPII coat complex component 4 109433772-109540896 Predicted intracellular proteins Evidence at protein level HPA038181 Approved Approved Nucleus
Vesicles Renal cancer:2.33e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 42.8 Expressed in all +C4orf17 DKFZP434G072 ENSG00000138813 Chromosome 4 open reading frame 17 4 99511004-99542303 Predicted intracellular proteins Evidence at protein level HPA060374, HPA060564 Uncertain Not detected Tissue enriched 352 testis: 35.2 all non-specific tissues: 0.0 Not detected +PPP3CA CALN, CALNA, CNA1, PPP2B ENSG00000138814 Protein phosphatase 3 catalytic subunit alpha 4 101023409-101348278 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012778, CAB018581 Enhanced Enhanced Nucleoplasm
Cytosol Pancreatic cancer:3.82e-4 (unfavourable) Tissue enriched Expressed in all cerebral cortex: 164.3 Expressed in all +SLC39A8 BIGM103 ENSG00000138821 Solute carrier family 39 member 8 4 102251041-102431258 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA038832, HPA038833 Approved Renal cancer:6.34e-6 (favourable), Colorectal cancer:1.34e-4 (favourable), Breast cancer:6.69e-4 (favourable) Expressed in all Tissue enhanced lung: 257.0 cervix, uterine: 129.4 Cell line enhanced BJ hTERT+: 128.9;Karpas-707: 123.0 +MTTP ABL, MTP ENSG00000138823 Microsomal triglyceride transfer protein 4 99563761-99623999 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051170, HPA054862 Uncertain Approved Cytosol Tissue enriched Group enriched 16 duodenum: 236.3;liver: 133.9;small intestine: 292.6 testis: 13.5 Cell line enhanced AF22: 10.2;Hep G2: 8.0 +FBN2 CCA, DA9 ENSG00000138829 Fibrillin 2 5 128257909-128659185 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012853, CAB026401 Enhanced Approved Nucleoplasm
Cytosol Urothelial cancer:7.41e-5 (unfavourable) Mixed Tissue enriched 9 placenta: 118.4 testis: 13.8 Cell line enhanced HHSteC: 116.8;hTERT-HME1: 171.2;HUVEC TERT2: 107.0 +MAPK8IP3 JIP3, JSAP1, KIAA1066, syd ENSG00000138834 Mitogen-activated protein kinase 8 interacting protein 3 16 1706183-1770317 Predicted intracellular proteins Evidence at protein level CAB005580, HPA041785, HPA069311 Approved Approved Vesicles Renal cancer:5.25e-5 (unfavourable), Urothelial cancer:3.95e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 83.9 Expressed in all +RGS3 C2PA, FLJ20370, PDZ-RGS3 ENSG00000138835 Regulator of G-protein signaling 3 9 113444731-113597743 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032507, HPA041109 Enhanced Nucleoplasm
Mitochondria
Cytosol Liver cancer:6.62e-4 (unfavourable), Breast cancer:9.93e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 66.4 Cell line enhanced BJ hTERT+: 201.8;HDLM-2: 382.8 +GUCD1 C22orf13, LLN4, MGC1842 ENSG00000138867 Guanylyl cyclase domain containing 1 22 24540423-24555935 Predicted intracellular proteins Evidence at protein level HPA022786 Approved Nucleoplasm Cervical cancer:6.84e-4 (favourable), Ovarian cancer:7.26e-4 (favourable) Expressed in all Expressed in all duodenum: 63.0 Expressed in all +TTLL8 ENSG00000138892 Tubulin tyrosine ligase like 8 22 50015123-50056935 Predicted intracellular proteins Evidence at transcript level HPA016882 Uncertain Not detected Tissue enriched 42 testis: 4.2 all non-specific tissues: 0.0 Not detected +RNF185 FLJ38628 ENSG00000138942 Ring finger protein 185 22 31160183-31207019 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:4.82e-5 (favourable) Expressed in all Expressed in all thyroid gland: 86.7 Expressed in all +KIAA1644 ENSG00000138944 KIAA1644 22 44243667-44312851 Predicted membrane proteins Evidence at transcript level HPA051178 Uncertain Approved Vesicles
Cytosol Mixed Tissue enhanced cerebral cortex: 27.6;endometrium: 42.8;smooth muscle: 44.6 cervix, uterine: 19.2 Cell line enhanced SiHa: 38.9;U-2197: 76.1;U-87 MG: 46.0;WM-115: 27.3 +PARVG ENSG00000138964 Parvin gamma 22 44172956-44219533 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031833, HPA031834 Uncertain Renal cancer:3.43e-6 (unfavourable), Endometrial cancer:4.44e-6 (favourable) Expressed in all Tissue enhanced spleen: 38.4 appendix: 35.4 Cell line enhanced HL-60: 92.2;NB-4: 28.2;THP-1: 43.6;U-937: 42.1 +B4GALNT3 B4GalNac-T3, FLJ16224, FLJ40362 ENSG00000139044 Beta-1,4-N-acetyl-galactosaminyltransferase 3 12 460364-563509 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011404 Enhanced Endometrial cancer:1.69e-10 (favourable) Mixed Tissue enhanced stomach: 69.3 colon: 21.5 Cell line enhanced BEWO: 37.3;NTERA-2: 17.2 +PDE6H ENSG00000139053 Phosphodiesterase 6H 12 14973022-14981865 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA045118 Supported Not detected Tissue enhanced bone marrow: 2.4;placenta: 1.3 adrenal gland: 0.5 Not detected +ERP27 C12orf46, ERp27, FLJ32115, PDIA8 ENSG00000139055 Endoplasmic reticulum protein 27 12 14914035-14939082 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039636, HPA052851 Enhanced Expressed in all Group enriched 10 fallopian tube: 104.4;pancreas: 282.3 kidney: 20.0 Cell line enhanced CAPAN-2: 16.3;RT4: 74.3 +ETV6 TEL ENSG00000139083 ETS variant 6 12 11649854-11895402 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000264 Enhanced Enhanced Nucleoli
Cytosol Renal cancer:4.66e-8 (unfavourable), Urothelial cancer:1.54e-5 (favourable), Pancreatic cancer:9.38e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 26.4 Cell line enhanced HDLM-2: 80.8 +GABARAPL1 APG8L, ATG8B, ATG8L, gec1 ENSG00000139112 GABA type A receptor associated protein like 1 12 10212458-10223130 Predicted intracellular proteins Evidence at protein level HPA051386, HPA065883 Approved Approved Vesicles Renal cancer:8.19e-8 (favourable), Liver cancer:2.36e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 432.0 Cell line enhanced HHSteC: 208.2;SiHa: 253.0 +KIF21A FEOM1, FLJ20052 ENSG00000139116 Kinesin family member 21A 12 39293228-39443390 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB022079, HPA058432 Enhanced Supported Plasma membrane
Cytosol Renal cancer:8.07e-8 (favourable) Expressed in all Tissue enhanced cerebral cortex: 75.0 fallopian tube: 54.6 Cell line enhanced SH-SY5Y: 199.8 +CPNE8 ENSG00000139117 Copine 8 12 38646822-38907430 Predicted intracellular proteins Evidence at protein level HPA038600 Approved Stomach cancer:2.11e-4 (unfavourable) Expressed in all Mixed placenta: 17.2 Cell line enhanced RPTEC TERT1: 49.5 +YARS2 CGI-04, FLJ13995, mt-TyrRS ENSG00000139131 Tyrosyl-tRNA synthetase 2 12 32727490-32755902 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038721, HPA057610, HPA074097 Uncertain Supported Nuclear bodies
Mitochondria Liver cancer:3.19e-5 (unfavourable) Expressed in all Mixed placenta: 11.1 Expressed in all +FGD4 CMT4H, frabin, FRABP, ZFYVE6 ENSG00000139132 FYVE, RhoGEF and PH domain containing 4 12 32399529-32646050 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039235 Approved Supported Actin filaments Renal cancer:7.16e-5 (favourable) Expressed in all Expressed in all ovary: 30.2 Mixed +ALG10 ALG10A, DIE2, FLJ14751 ENSG00000139133 ALG10, alpha-1,2-glucosyltransferase 12 34022281-34029694 Enzymes, Predicted membrane proteins Evidence at protein level HPA043329, HPA063387 Approved Approved Endoplasmic reticulum Mixed Mixed parathyroid gland: 4.6 Expressed in all +PIK3C2G ENSG00000139144 Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma 12 18247614-18648416 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Pancreatic cancer:3.50e-4 (unfavourable) Tissue enhanced Tissue enhanced epididymis: 20.4;stomach: 20.0 parathyroid gland: 17.3 Group enriched 6 BEWO: 1.2;HaCaT: 1.8;hTERT-HME1: 2.9 +FAM60A C12orf14, TERA ENSG00000139146 Family with sequence similarity 60 member A 12 31280584-31327058 Predicted intracellular proteins Evidence at protein level HPA038167, HPA057585 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:5.57e-4 (unfavourable), Liver cancer:5.78e-4 (unfavourable), Renal cancer:7.89e-4 (favourable) Expressed in all Mixed endometrium: 44.5 Expressed in all +PLCZ1 NYD-SP27, PLCzeta ENSG00000139151 Phospholipase C zeta 1 12 18683169-18738057 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 23 testis: 48.5 skin: 2.1 Not detected +AEBP2 MGC17922 ENSG00000139154 AE binding protein 2 12 19404045-19720801 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020893, HPA022282 Uncertain Supported Nucleus Liver cancer:3.24e-4 (unfavourable) Expressed in all Expressed in all placenta: 57.5 Expressed in all +SLCO1C1 OATP-F, OATP1, OATP1C1, SLC21A14 ENSG00000139155 Solute carrier organic anion transporter family member 1C1 12 20695355-20753386 Predicted membrane proteins, Transporters Evidence at transcript level Tissue enriched Tissue enriched 10 cerebral cortex: 27.5 testis: 2.6 Cell line enriched 9 HeLa: 2.7 +ETFBKMT C12orf72, DKFZp451L235, METTL20, MGC50559 ENSG00000139160 Electron transfer flavoprotein beta subunit lysine methyltransferase 12 31647160-31673114 Predicted intracellular proteins Evidence at protein level HPA039024 Uncertain Mixed Mixed parathyroid gland: 8.8 Mixed +ETNK1 EKI, EKI1 ENSG00000139163 Ethanolamine kinase 1 12 22625075-22690665 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010712, HPA029407 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:1.75e-4 (favourable), Liver cancer:5.85e-4 (unfavourable) Expressed in all Expressed in all stomach: 45.6 Expressed in all +ZCRB1 MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19 ENSG00000139168 Zinc finger CCHC-type and RNA binding motif containing 1 12 42312078-42326118 Predicted intracellular proteins Evidence at protein level Liver cancer:5.33e-7 (unfavourable), Renal cancer:1.37e-6 (unfavourable), Ovarian cancer:7.33e-4 (favourable) Expressed in all Expressed in all testis: 153.7 Expressed in all +TMEM117 DKFZp434K2435 ENSG00000139173 Transmembrane protein 117 12 43835967-44389762 Predicted membrane proteins Evidence at transcript level HPA039899, HPA046223 Uncertain Approved Nucleus
Nucleoli
Plasma membrane
Cytokinetic bridge Melanoma:3.94e-4 (unfavourable) Expressed in all Mixed seminal vesicle: 7.3 Mixed +PRICKLE1 EPM1B, FLJ31937, RILP ENSG00000139174 Prickle planar cell polarity protein 1 12 42456757-42590355 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001379, HPA050037 Enhanced Approved Nucleoplasm Glioma:5.56e-4 (unfavourable) Mixed Mixed cerebral cortex: 21.2 Cell line enriched 13 HBEC3-KT: 727.1 +C1RL C1r-LP, C1RL1 ENSG00000139178 Complement C1r subcomponent like 12 7089587-7109273 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011338, CAB026172 Supported Approved Microtubules
Cytosol Renal cancer:1.52e-7 (unfavourable), Breast cancer:7.92e-4 (favourable) Expressed in all Expressed in all liver: 83.7 Cell line enhanced HSkMC: 60.9 +NDUFA9 CI-39k, NDUFS2L, SDR22E1 ENSG00000139180 NADH:ubiquinone oxidoreductase subunit A9 12 4649095-4694317 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042268, HPA073212 Enhanced Supported Nucleoplasm
Mitochondria Renal cancer:2.57e-7 (favourable), Urothelial cancer:5.75e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 38.4 Expressed in all +CLSTN3 CDHR14, CSTN3, KIAA0726 ENSG00000139182 Calsyntenin 3 12 7129698-7158945 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Pancreatic cancer:1.19e-5 (favourable), Renal cancer:4.49e-5 (unfavourable), Breast cancer:5.08e-4 (favourable), Urothelial cancer:8.07e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 126.6 parathyroid gland: 40.3 Mixed +KLRG1 2F1, CLEC15A, MAFA, MAFA-L ENSG00000139187 Killer cell lectin like receptor G1 12 8950044-9010760 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051403, HPA076494 Supported Vesicles Mixed Tissue enhanced spleen: 15.8 lymph node: 13.5 Cell line enhanced HEL: 29.9;NTERA-2: 22.2;U-937: 16.1 +VAMP1 SYB1, VAMP-1 ENSG00000139190 Vesicle associated membrane protein 1 12 6462237-6470987 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB002779, CAB016119, CAB079000 Approved Approved Renal cancer:1.04e-11 (unfavourable), Colorectal cancer:6.37e-5 (unfavourable), Liver cancer:6.97e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 43.5 Cell line enriched 5 U-698: 140.4 +TAPBPL FLJ10143, TAPBP-R, TAPBPR ENSG00000139192 TAP binding protein like 12 6451690-6466517 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA039545 Uncertain Renal cancer:6.04e-5 (favourable), Breast cancer:1.98e-4 (favourable), Urothelial cancer:7.86e-4 (favourable) Expressed in all Expressed in all thyroid gland: 39.2 Cell line enhanced CAPAN-2: 58.5 +CD27 S152, TNFRSF7, Tp55 ENSG00000139193 CD27 molecule 12 6444867-6451718 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002420, HPA038936 Enhanced Head and neck cancer:6.65e-7 (favourable), Renal cancer:1.19e-6 (unfavourable), Cervical cancer:3.77e-5 (favourable), Endometrial cancer:2.90e-4 (favourable), Melanoma:5.50e-4 (favourable) Expressed in all Tissue enhanced lymph node: 140.5;tonsil: 85.8 spleen: 67.8 Group enriched 122 Daudi: 153.8;U-698: 81.7 +RBP5 CRBPIII ENSG00000139194 Retinol binding protein 5 12 7123684-7128942 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038723 Enhanced Approved Golgi apparatus
Vesicles Urothelial cancer:3.68e-4 (favourable), Lung cancer:8.37e-4 (favourable) Group enriched Tissue enhanced kidney: 455.7;liver: 204.9 spleen: 102.0 Cell line enhanced Hep G2: 17.0;K-562: 46.6 +PEX5 PTS1R, PXR1 ENSG00000139197 Peroxisomal biogenesis factor 5 12 7188685-7218574 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039259, HPA039260 Enhanced Supported Golgi apparatus
Cytosol Expressed in all Expressed in all testis: 81.3 Expressed in all +PIANP C12orf53, DKFZp547D2210, PANP ENSG00000139200 PILR alpha associated neural protein 12 6693792-6700800 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010631 Enhanced Approved Nucleoplasm Tissue enhanced Tissue enhanced cerebral cortex: 64.3 endometrium: 13.4 Cell line enhanced NTERA-2: 20.8;SH-SY5Y: 20.6;U-2 OS: 11.2 +SLC38A4 ATA3, NAT3, PAAT ENSG00000139209 Solute carrier family 38 member 4 12 46764761-46832408 Predicted membrane proteins, Transporters Evidence at protein level Liver cancer:5.37e-4 (favourable) Tissue enriched Tissue enriched 40 liver: 346.9 smooth muscle: 8.7 Cell line enhanced LHCN-M2: 37.9;RH-30: 14.5;RT4: 71.7 +AMIGO2 ALI1, DEGA ENSG00000139211 Adhesion molecule with Ig like domain 2 12 47075707-47079951 Predicted membrane proteins Evidence at protein level HPA054004, HPA059601 Uncertain Approved Golgi apparatus
Plasma membrane
Cytosol Pancreatic cancer:1.80e-4 (unfavourable) Expressed in all Mixed smooth muscle: 55.1 Cell line enhanced CAPAN-2: 184.4;fHDF/TERT166: 158.6;LHCN-M2: 167.5;RT4: 222.6;U-2 OS: 170.3 +SCAF11 CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP ENSG00000139218 SR-related CTD associated factor 11 12 45919131-45992120 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038862, HPA045456, HPA046345 Enhanced Enhanced Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 84.9 Expressed in all +COL2A1 AOM, SEDC, STL1 ENSG00000139219 Collagen type II alpha 1 chain 12 47972965-48004486 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level CAB002214, HPA055753 Supported Approved Nucleoplasm Mixed Group enriched 9 epididymis: 23.0;stomach: 6.2 prostate: 1.6 Group enriched 23 AF22: 154.1;HAP1: 101.9;HEK 293: 33.7 +PPFIA2 ENSG00000139220 PTPRF interacting protein alpha 2 12 81257975-81759553 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 5 cerebral cortex: 61.0 testis: 11.4 Group enriched 9 HAP1: 30.3;SCLC-21H: 11.7 +ANP32D PP32R2 ENSG00000139223 Acidic nuclear phosphoprotein 32 family member D 12 48472665-48473624 Predicted intracellular proteins Evidence at protein level HPA063133, HPA067561 Uncertain Enhanced Nucleoplasm
Centrosome
Cytosol Not detected Not detected testis,thyroid gland: 0.1 Not detected +LLPH C12orf31, hLLP, MGC14817 ENSG00000139233 LLP homolog, long-term synaptic facilitation 12 66116555-66130768 Predicted intracellular proteins Evidence at protein level HPA048920, HPA058786 Enhanced Nucleoli Liver cancer:6.44e-7 (unfavourable) Expressed in all Expressed in all adrenal gland: 42.5 Expressed in all +LRIG3 FLJ90440, KIAA3016 ENSG00000139263 Leucine rich repeats and immunoglobulin like domains 3 12 58872149-58920522 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010773 Approved Approved Cytosol Expressed in all Tissue enhanced thyroid gland: 97.8 skin: 33.0 Mixed +MARCH9 FLJ36578, RNF179 ENSG00000139266 Membrane associated ring-CH-type finger 9 12 57755098-57760407 Enzymes, Predicted membrane proteins Evidence at protein level Lung cancer:1.54e-5 (favourable), Renal cancer:2.98e-5 (favourable), Ovarian cancer:1.59e-4 (favourable), Endometrial cancer:3.07e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.3 Cell line enriched 16 RH-30: 498.8 +INHBE activin, MGC4638 ENSG00000139269 Inhibin beta E subunit 12 57452323-57459280 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA016843, CAB034017 Enhanced Approved Vesicles Renal cancer:5.66e-8 (unfavourable) Tissue enriched Tissue enriched 28 liver: 68.1 thyroid gland: 2.4 Cell line enhanced HHSteC: 43.4;Karpas-707: 57.3;U-266/70: 203.5 +GLIPR1 GliPR, RTVP1 ENSG00000139278 GLI pathogenesis related 1 12 75480680-75503853 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011014 Approved Renal cancer:8.69e-9 (unfavourable) Expressed in all Mixed appendix: 64.9 Cell line enhanced hTEC/SVTERT24-B: 189.5;U-138 MG: 359.6 +TPH2 FLJ37295, NTPH ENSG00000139287 Tryptophan hydroxylase 2 12 71938846-72186618 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA046274, CAB078198 Enhanced Supported Not detected Tissue enhanced cerebral cortex: 1.0 testis: 0.2 Not detected +PHLDA1 DT1P1B11, PHRIP, TDAG51 ENSG00000139289 Pleckstrin homology like domain family A member 1 12 76025447-76033932 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB016160, HPA019000, HPA063520 Approved Supported Nucleoli Expressed in all Mixed salivary gland: 68.6 Mixed +TMEM19 FLJ10936 ENSG00000139291 Transmembrane protein 19 12 71686087-71705046 Predicted membrane proteins Evidence at protein level HPA016830 Approved Expressed in all Expressed in all kidney: 40.8 Expressed in all +LGR5 FEX, GPR49, GPR67, HG38 ENSG00000139292 Leucine rich repeat containing G protein-coupled receptor 5 12 71439770-71586310 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA012530 Approved Lung cancer:5.09e-4 (favourable) Group enriched Tissue enhanced fallopian tube: 26.6;placenta: 26.9 seminal vesicle: 9.8 Group enriched 6 Hep G2: 25.0;SH-SY5Y: 110.2 +PTPRQ DFNB84 ENSG00000139304 Protein tyrosine phosphatase, receptor type Q 12 80402178-80680234 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053245 Uncertain Approved Cytosol Not detected Tissue enhanced testis: 4.9 lung: 3.4 Cell line enhanced ASC TERT1: 3.4;BJ: 3.3;HBF TERT88: 2.6;RH-30: 2.8;RT4: 2.7;U-2197: 2.9 +DUSP6 MKP-3, PYST1 ENSG00000139318 Dual specificity phosphatase 6 12 89347232-89353271 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB017566, HPA053188 Approved Uncertain Nucleoplasm
Cytosol Endometrial cancer:7.21e-4 (favourable) Expressed in all Expressed in all thyroid gland: 141.2 Cell line enhanced AN3-CA: 428.0 +POC1B FLJ14923, TUWD12, WDR51B ENSG00000139323 POC1 centriolar protein B 12 89419718-89526024 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:3.45e-6 (favourable), Endometrial cancer:9.59e-5 (favourable) Expressed in all Expressed in all fallopian tube: 19.8 Expressed in all +TMTC3 FLJ90492, SMILE ENSG00000139324 Transmembrane and tetratricopeptide repeat containing 3 12 88142296-88199887 Disease related genes, Predicted membrane proteins Evidence at protein level HPA038550 Approved Expressed in all Mixed skin: 14.9 Expressed in all +LUM LDC, SLRR2D ENSG00000139329 Lumican 12 91102629-91111831 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001522, CAB025783 Supported Renal cancer:1.75e-6 (unfavourable) Expressed in all Tissue enhanced gallbladder: 929.5 placenta: 602.2 Cell line enhanced BJ: 269.9;BJ hTERT+: 1272.0;fHDF/TERT166: 208.2 +KERA CNA2, SLRR2B ENSG00000139330 Keratocan 12 91050491-91057983 Disease related genes, Predicted secreted proteins Evidence at protein level HPA039321 Uncertain Mixed Tissue enhanced gallbladder: 1.5 breast,fallopian tube: 0.8 Not detected +SNRPF Sm-F ENSG00000139343 Small nuclear ribonucleoprotein polypeptide F 12 95858928-95903828 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.11e-6 (unfavourable) Expressed in all Expressed in all appendix: 36.8 Expressed in all +AMDHD1 MGC35366 ENSG00000139344 Amidohydrolase domain containing 1 12 95943293-95968716 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039720 Uncertain Approved Plasma membrane
Actin filaments
Focal adhesion sites Tissue enriched Tissue enhanced testis: 25.8 liver: 22.0 Cell line enhanced HMC-1: 57.9;Karpas-707: 44.7;SiHa: 44.1;U-266/84: 42.8 +NEDD1 GCP-WD, TUBGCP7 ENSG00000139350 Neural precursor cell expressed, developmentally down-regulated 1 12 96907223-96953777 Predicted intracellular proteins Evidence at protein level HPA038591 Approved Liver cancer:1.94e-4 (unfavourable), Lung cancer:3.70e-4 (unfavourable) Expressed in all Expressed in all testis: 42.9 Expressed in all +SYCP3 ENSG00000139351 Synaptonemal complex protein 3 12 101728648-101739472 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB032978, HPA039635, HPA043938 Enhanced Tissue enriched Tissue enriched 265 testis: 172.2 lung: 0.6 Cell line enhanced Karpas-707: 1.0 +ASCL1 ASH1, bHLHa46, HASH1 ENSG00000139352 Achaete-scute family bHLH transcription factor 1 12 102957686-102960516 Predicted secreted proteins, Transcription factors Evidence at protein level HPA029217 Enhanced Group enriched Group enriched 8 cerebral cortex: 16.2;liver: 6.4 adrenal gland: 1.4 Group enriched 23 SCLC-21H: 63.4;SH-SY5Y: 30.9 +GAS2L3 ENSG00000139354 Growth arrest specific 2 like 3 12 100573683-100628286 Predicted intracellular proteins Evidence at protein level HPA048593 Approved Renal cancer:3.58e-7 (unfavourable) Mixed Mixed gallbladder: 7.0 Mixed +TMEM132B KIAA1786, KIAA1906 ENSG00000139364 Transmembrane protein 132B 12 125186836-125662377 Predicted membrane proteins Evidence at protein level HPA035661, HPA035662 Uncertain Tissue enriched Tissue enriched 7 cerebral cortex: 21.8 thyroid gland: 3.1 Cell line enhanced HSkMC: 4.8;NTERA-2: 7.7;U-138 MG: 11.6 +SLC15A4 PHT1, PTR4 ENSG00000139370 Solute carrier family 15 member 4 12 128793191-128823983 Predicted membrane proteins, Transporters Evidence at protein level HPA016713 Approved Supported Nucleoplasm Renal cancer:7.56e-6 (unfavourable), Liver cancer:6.78e-4 (unfavourable), Head and neck cancer:8.45e-4 (unfavourable) Expressed in all Expressed in all endometrium,testis: 20.2 Mixed +TDG ENSG00000139372 Thymine DNA glycosylase 12 103965804-103988874 Enzymes, Predicted intracellular proteins Evidence at protein level HPA052263 Supported Supported Nucleoplasm Renal cancer:1.90e-10 (unfavourable), Liver cancer:6.27e-5 (unfavourable), Melanoma:6.90e-5 (unfavourable) Expressed in all Expressed in all placenta: 23.8 Expressed in all +RITA1 C12orf52, FLJ14827, RITA ENSG00000139405 RBPJ interacting and tubulin associated 1 12 113185526-113192368 Predicted intracellular proteins Evidence at protein level HPA039094, HPA039095, HPA061531 Supported Supported Nucleus Liver cancer:9.79e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 20.4 Expressed in all +SDSL cSDH, SDS-RS1 ENSG00000139410 Serine dehydratase like 12 113422237-113438276 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA005740 Approved Approved Cytosol Renal cancer:3.09e-5 (favourable), Pancreatic cancer:8.58e-4 (favourable) Expressed in all Mixed thyroid gland: 35.2 Cell line enhanced MCF7: 64.8 +MMAB cblB, CFAP23 ENSG00000139428 Methylmalonic aciduria (cobalamin deficiency) cblB type 12 109553737-109573874 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039017 Approved Approved Mitochondria Renal cancer:1.55e-4 (favourable) Expressed in all Expressed in all adrenal gland: 32.5 Expressed in all +GLTP ENSG00000139433 Glycolipid transfer protein 12 109850943-109880488 Predicted intracellular proteins Evidence at protein level HPA056461 Approved Supported Cytosol Thyroid cancer:4.17e-6 (favourable), Cervical cancer:2.01e-5 (favourable), Liver cancer:7.68e-4 (unfavourable) Expressed in all Expressed in all skin: 293.8 Expressed in all +GIT2 KIAA0148, PKL ENSG00000139436 GIT ArfGAP 2 12 109929792-109996389 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004681 Approved Approved Microtubules Renal cancer:2.93e-4 (unfavourable) Expressed in all Expressed in all spleen: 47.9 Expressed in all +TCHP MGC10854, TpMs ENSG00000139437 Trichoplein keratin filament binding 12 109900264-109983841 Predicted intracellular proteins Evidence at protein level HPA038638, HPA061543 Supported Supported Plasma membrane
Centrosome
Cytosol Stomach cancer:5.52e-4 (favourable) Expressed in all Expressed in all skin: 32.6 Expressed in all +FAM222A C12orf34, FLJ14721 ENSG00000139438 Family with sequence similarity 222 member A 12 109714228-109770507 Predicted intracellular proteins Evidence at protein level HPA040181 Uncertain Approved Nucleoplasm
Plasma membrane
Focal adhesion sites
Mitochondria Cervical cancer:1.82e-5 (favourable), Pancreatic cancer:4.81e-4 (favourable), Stomach cancer:8.59e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 20.0;testis: 16.5 adrenal gland: 9.8 Cell line enriched 5 SH-SY5Y: 122.9 +FOXN4 ENSG00000139445 Forkhead box N4 12 109277979-109309220 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050018 Uncertain Approved Nucleus
Mitochondria
Cytosol Tissue enhanced Tissue enriched 13 testis: 10.7 cervix, uterine: 0.8 Cell line enhanced SCLC-21H: 4.2;SH-SY5Y: 3.9;U-266/70: 3.9 +NUP58 KIAA0410, NUP45, NUPL1 ENSG00000139496 Nucleoporin 58 13 25301524-25349800 Predicted intracellular proteins, Transporters Evidence at protein level HPA039360 Approved Approved Plasma membrane
Mitochondria
Cytosol Cervical cancer:2.57e-4 (unfavourable), Liver cancer:3.56e-4 (unfavourable) Expressed in all Expressed in all testis: 87.0 Expressed in all +MTMR6 ENSG00000139505 Myotubularin related protein 6 13 25246201-25288009 Plasma proteins, Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all testis: 30.6 Expressed in all +SLC46A3 DKFZp686A1775, FLJ42613 ENSG00000139508 Solute carrier family 46 member 3 13 28700064-28718970 Predicted membrane proteins, Transporters Evidence at protein level HPA039930 Uncertain Approved Plasma membrane
Actin filaments
Cytosol Lung cancer:7.09e-4 (favourable) Expressed in all Expressed in all small intestine: 87.7 Cell line enhanced RPTEC TERT1: 22.1 +SLC7A1 ATRC1, CAT-1, ERR, HCAT1, REC1L ENSG00000139514 Solute carrier family 7 member 1 13 29509410-29595688 Predicted membrane proteins, Transporters Evidence at protein level HPA039721 Approved Renal cancer:1.32e-5 (unfavourable) Expressed in all Mixed esophagus: 41.8 Expressed in all +PDX1 IDX-1, IPF1, MODY4, PDX-1, STF-1 ENSG00000139515 Pancreatic and duodenal homeobox 1 13 27920020-27926231 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB025873, HPA059146 Enhanced Supported Nucleoplasm Group enriched Tissue enriched 7 duodenum: 43.6 stomach: 6.2 Group enriched 6 AN3-CA: 1.2;CACO-2: 1.0;CAPAN-2: 1.2;HDLM-2: 3.9;HEK 293: 2.2;HeLa: 4.1 +LNX2 MGC46315, PDZRN1 ENSG00000139517 Ligand of numb-protein X 2 13 27545911-27620404 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040698 Approved Approved Vesicles
Plasma membrane
Cytosol Renal cancer:7.09e-13 (favourable) Expressed in all Expressed in all testis: 23.3 Expressed in all +SUOX ENSG00000139531 Sulfite oxidase 12 55997180-56006641 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038208, HPA038209 Approved Renal cancer:4.77e-7 (favourable), Urothelial cancer:8.32e-5 (favourable), Pancreatic cancer:6.28e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 108.9 Mixed +CCDC65 CFAP250, CILD27, DRC2, FAP250, FLJ35732, NYD-SP28 ENSG00000139537 Coiled-coil domain containing 65 12 48904110-48931840 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038520, HPA057573 Uncertain Approved Vesicles
Microtubule organizing center Mixed Group enriched 12 fallopian tube: 42.8;testis: 67.9 lung: 4.4 Mixed +SLC39A5 ENSG00000139540 Solute carrier family 39 member 5 12 56230049-56237846 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA018423 Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:5.05e-4 (favourable) Tissue enhanced Group enriched 12 colon: 73.2;duodenum: 240.2;kidney: 115.0;liver: 86.0;pancreas: 53.1;rectum: 48.9;small intestine: 240.4 gallbladder: 10.0 Group enriched 62 CACO-2: 33.1;Hep G2: 39.7 +TARBP2 Trbp ENSG00000139546 TARBP2, RISC loading complex RNA binding subunit 12 53500921-53506431 Predicted intracellular proteins Evidence at protein level HPA051181, HPA061454, CAB069406 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:4.75e-6 (unfavourable), Liver cancer:3.09e-4 (unfavourable) Expressed in all Expressed in all placenta: 18.9 Expressed in all +RDH16 RODH-4, SDR9C8 ENSG00000139547 Retinol dehydrogenase 16 (all-trans) 12 56951431-56959374 Predicted membrane proteins Evidence at protein level HPA038518 Enhanced Liver cancer:2.16e-5 (favourable) Tissue enriched Tissue enriched 85 liver: 278.6 prostate: 3.2 Cell line enhanced HaCaT: 1.1;hTCEpi: 2.0 +DHH HHG-3, MGC35145 ENSG00000139549 Desert hedgehog 12 49089421-49094819 Disease related genes, Predicted secreted proteins Evidence at protein level Mixed Tissue enriched 21 testis: 20.7 appendix,placenta: 0.9 Group enriched 8 AN3-CA: 2.1;EFO-21: 4.6;HUVEC TERT2: 1.7;K-562: 7.8;TIME: 3.7 +ACVRL1 ACVRLK1, ALK1, HHT, HHT2, ORW2 ENSG00000139567 Activin A receptor like type 1 12 51906908-51923361 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007041 Approved Expressed in all Tissue enhanced placenta: 126.4 lung: 76.4 Cell line enhanced ASC diff: 42.2;EFO-21: 52.0;HUVEC TERT2: 171.4;TIME: 130.8 +GPR84 EX33 ENSG00000139572 G protein-coupled receptor 84 12 54362445-54364487 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA027603 Enhanced Mixed Tissue enhanced appendix: 11.6;bone marrow: 14.7 adipose tissue: 6.0 Cell line enhanced HL-60: 10.3;NB-4: 25.5;U-937: 4.0 +NPFF FMRFAL ENSG00000139574 Neuropeptide FF-amide peptide precursor 12 53506690-53507638 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 1231 epididymis: 1000.1 duodenum: 0.8 Cell line enriched 6 HHSteC: 11.2 +NABP2 hSSB1, MGC2731, OBFC2B, SOSS-B1, SSB1 ENSG00000139579 Nucleic acid binding protein 2 12 56222015-56229854 Predicted intracellular proteins Evidence at protein level HPA044615, HPA057213 Supported Enhanced Nucleoplasm Liver cancer:7.44e-6 (unfavourable), Cervical cancer:8.35e-6 (favourable), Renal cancer:2.69e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 42.0 Expressed in all +N4BP2L1 CG018 ENSG00000139597 NEDD4 binding protein 2 like 1 13 32400723-32428311 Predicted intracellular proteins Evidence at protein level HPA038971 Approved Uncertain Nucleoplasm
Cytosol Liver cancer:3.11e-4 (favourable) Expressed in all Expressed in all ovary: 47.8 Cell line enhanced HEL: 21.3;NB-4: 38.0 +CELA1 ELA1 ENSG00000139610 Chymotrypsin like elastase family member 1 12 51328443-51346679 Enzymes, Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enhanced adrenal gland: 2.5;pancreas: 1.3 lymph node: 0.9 Cell line enriched 6 BEWO: 5.2 +SMARCC2 BAF170, CRACC2, Rsc8 ENSG00000139613 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 12 56162983-56189567 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004321, HPA021213, HPA061788 Supported Enhanced Nucleoplasm Expressed in all Expressed in all cerebral cortex: 76.8 Expressed in all +BRCA2 BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11 ENSG00000139618 BRCA2, DNA repair associated 13 32315474-32400266 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026815 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced testis: 5.2 bone marrow: 4.1 Mixed +KANSL2 C12orf41, FLJ20436, NSL2 ENSG00000139620 KAT8 regulatory NSL complex subunit 2 12 48653401-48682238 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038497, HPA038498 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:4.32e-4 (favourable), Liver cancer:4.98e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 31.9 Expressed in all +CERS5 FLJ25304, LASS5, MGC45411, Trh4 ENSG00000139624 Ceramide synthase 5 12 50129306-50167533 Enzymes, Predicted membrane proteins Evidence at protein level HPA026589 Approved Approved Nucleus
Nucleoli Renal cancer:9.33e-11 (unfavourable), Liver cancer:4.63e-5 (unfavourable), Thyroid cancer:5.76e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 36.4 Expressed in all +MAP3K12 DLK, MEKK12, MUK, ZPK, ZPKP1 ENSG00000139625 Mitogen-activated protein kinase kinase kinase 12 12 53479669-53500063 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039936, HPA071996 Approved Approved Nucleus
Cell Junctions Renal cancer:5.43e-10 (unfavourable), Pancreatic cancer:1.51e-4 (favourable) Mixed Mixed gallbladder: 23.9 Cell line enhanced HHSteC: 46.6 +ITGB7 ENSG00000139626 Integrin subunit beta 7 12 53191318-53207307 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA042277 Approved Plasma membrane
Cytosol Mixed Mixed spleen: 32.5 Group enriched 97 Karpas-707: 3399.5;RPMI-8226: 2658.1 +GALNT6 GalNAc-T6 ENSG00000139629 Polypeptide N-acetylgalactosaminyltransferase 6 12 51351247-51392867 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011762, HPA017086 Enhanced Approved Nucleoplasm
Golgi apparatus Ovarian cancer:5.40e-4 (favourable), Endometrial cancer:9.85e-4 (favourable) Mixed Tissue enhanced stomach: 61.5 cervix, uterine: 49.5 Mixed +CSAD CSD, PCAP ENSG00000139631 Cysteine sulfinic acid decarboxylase 12 53157663-53180909 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039487 Approved Renal cancer:1.93e-6 (unfavourable), Urothelial cancer:6.81e-6 (favourable), Liver cancer:1.37e-4 (favourable), Pancreatic cancer:3.39e-4 (favourable), Head and neck cancer:6.33e-4 (favourable), Colorectal cancer:9.50e-4 (unfavourable) Expressed in all Expressed in all skin: 70.7 Cell line enhanced ASC diff: 57.9;T-47d: 49.5 +LMBR1L FLJ10494, KIAA1174 ENSG00000139636 Limb development membrane protein 1 like 12 49096551-49110900 Predicted membrane proteins Evidence at protein level Renal cancer:4.45e-7 (unfavourable), Colorectal cancer:1.04e-4 (unfavourable), Pancreatic cancer:3.50e-4 (favourable) Expressed in all Tissue enhanced testis: 27.9 endometrium: 9.1 Expressed in all +C12orf10 Gamm1, MYG, MYG1 ENSG00000139637 Chromosome 12 open reading frame 10 12 53299686-53307177 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038626, HPA038627 Approved Supported Supported Nucleoplasm Expressed in all Expressed in all testis: 114.3 Expressed in all +ESYT1 FAM62A, KIAA0747, MBC2 ENSG00000139641 Extended synaptotagmin 1 12 56118250-56144671 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA016858, HPA076926 Approved Supported Endoplasmic reticulum Renal cancer:3.86e-4 (favourable) Expressed in all Expressed in all adipose tissue: 114.6 Expressed in all +TMBIM6 BAXI1, BI-1, TEGT ENSG00000139644 Transmembrane BAX inhibitor motif containing 6 12 49707725-49764934 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA017378 Approved Renal cancer:1.00e-5 (favourable), Head and neck cancer:1.91e-4 (unfavourable), Breast cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all kidney: 1188.4 Expressed in all +ANKRD52 FLJ34236, PP6-ARS-C ENSG00000139645 Ankyrin repeat domain 52 12 56237807-56258391 Predicted intracellular proteins Evidence at protein level HPA043815 Uncertain Approved Nucleoplasm
Mitochondria Liver cancer:3.33e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 31.0 Expressed in all +KRT71 K6IRS1, KRT6IRS, KRT6IRS1 ENSG00000139648 Keratin 71 12 52543909-52553147 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049404 Supported Tissue enhanced Group enriched 34 breast: 1.4;epididymis: 5.3 all non-specific tissues: 0.0 Cell line enriched 11 CACO-2: 5.1 +ZNF740 Zfp740 ENSG00000139651 Zinc finger protein 740 12 53180700-53195141 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035691 Approved Approved Nucleus Melanoma:4.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 14.3 Expressed in all +SMIM2 C13orf44, MGC5590 ENSG00000139656 Small integral membrane protein 2 13 44143543-44161257 Predicted membrane proteins Evidence at protein level HPA026891 Enhanced Not detected Tissue enriched 8 testis: 30.0 epididymis: 3.6 Cell line enhanced BJ hTERT+: 2.1;SiHa: 2.1 +WDFY2 ZFYVE22 ENSG00000139668 WD repeat and FYVE domain containing 2 13 51584455-51767707 Predicted intracellular proteins Evidence at protein level Expressed in all Mixed skin: 21.3 Expressed in all +HNRNPA1L2 LOC144983 ENSG00000139675 Heterogeneous nuclear ribonucleoprotein A1-like 2 13 52640786-52643796 Predicted intracellular proteins Evidence at protein level Breast cancer:2.58e-4 (favourable), Pancreatic cancer:4.26e-4 (favourable) Expressed in all Mixed ovary: 6.0 Expressed in all +LPAR6 P2RY5, P2Y5 ENSG00000139679 Lysophosphatidic acid receptor 6 13 48389567-48444704 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA028934, HPA076273 Approved Supported Vesicles
Plasma membrane Renal cancer:3.60e-4 (unfavourable), Lung cancer:6.22e-4 (favourable) Expressed in all Expressed in all placenta: 100.9 Cell line enhanced AF22: 19.1;HUVEC TERT2: 26.4 +ESD ENSG00000139684 Esterase D 13 46771256-46797232 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039700 Approved Approved Golgi apparatus
Cytosol Head and neck cancer:2.16e-4 (unfavourable), Cervical cancer:5.01e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 245.7 Expressed in all +RB1 OSRC, PPP1R130, RB ENSG00000139687 RB transcriptional corepressor 1 13 48303751-48481986 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB000095, CAB016687, HPA050082 Supported Enhanced Nucleoplasm Ovarian cancer:6.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 36.1 Mixed +SBNO1 FLJ10701, FLJ10833, MOP3, Sno ENSG00000139697 Strawberry notch homolog 1 12 123289109-123364843 Predicted intracellular proteins Evidence at protein level HPA042388 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 126.2 Expressed in all +MORN3 ENSG00000139714 MORN repeat containing 3 12 121648742-121672631 Predicted intracellular proteins Evidence at protein level HPA038709, HPA038710 Uncertain Approved Nucleoplasm Breast cancer:1.16e-4 (favourable) Mixed Tissue enhanced fallopian tube: 6.7 testis: 5.1 Group enriched 7 BEWO: 14.7;CACO-2: 7.0 +SETD1B KIAA1076, KMT2G, Set1B ENSG00000139718 SET domain containing 1B 12 121804180-121832584 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021667, HPA059412 Approved Enhanced Nucleoplasm Expressed in all Expressed in all endometrium: 19.0 Expressed in all +VPS33A ENSG00000139719 VPS33A, CORVET/HOPS core subunit 12 122229564-122266521 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038701 Approved Nucleoplasm Liver cancer:9.11e-5 (unfavourable), Thyroid cancer:2.41e-4 (favourable), Renal cancer:5.29e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 13.8 Expressed in all +VPS37B FLJ12750 ENSG00000139722 VPS37B, ESCRT-I subunit 12 122865328-122896444 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038217, HPA038218 Enhanced Renal cancer:1.35e-6 (favourable) Expressed in all Expressed in all esophagus: 34.8 Mixed +RHOF ARHF, FLJ20247, RIF ENSG00000139725 Ras homolog family member F, filopodia associated 12 121777754-121803403 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045912, HPA076019 Enhanced Uncertain Nucleus
Golgi apparatus Mixed Expressed in all lymph node: 46.0 Cell line enhanced CAPAN-2: 112.6;HDLM-2: 171.6;PC-3: 116.5 +DENR DRP, DRP1, SMAP-3 ENSG00000139726 Density regulated re-initiation and release factor 12 122752774-122771064 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021783 Approved Approved Cytosol Liver cancer:1.58e-7 (unfavourable), Renal cancer:8.57e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 108.3 Expressed in all +DIAPH3 AN, AUNA1, DRF3, FLJ34705, NSDAN ENSG00000139734 Diaphanous related formin 3 13 59665583-60163987 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA032151 Supported Plasma membrane
Microtubules Lung cancer:3.72e-4 (unfavourable), Endometrial cancer:4.18e-4 (unfavourable), Colorectal cancer:9.04e-4 (favourable) Mixed Tissue enriched 7 testis: 34.0 placenta: 5.0 Mixed +SLAIN1 C13orf32, FLJ30046 ENSG00000139737 SLAIN motif family member 1 13 77697854-77764242 Predicted intracellular proteins Evidence at protein level HPA040798 Approved Nucleoplasm
Intermediate filaments
Cytosol Ovarian cancer:9.07e-4 (favourable) Tissue enhanced Expressed in all cerebral cortex: 217.1 Cell line enhanced HL-60: 61.7;MOLT-4: 72.0;SCLC-21H: 69.0 +RBM26 ARRS2, C13orf10, FLJ20957, PPP1R132, PRO1777, SE70-2, ZC3H17 ENSG00000139746 RNA binding motif protein 26 13 79311824-79406477 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040252 Approved Approved Nuclear speckles Renal cancer:5.87e-6 (unfavourable), Prostate cancer:3.46e-4 (unfavourable), Urothelial cancer:8.20e-4 (favourable) Expressed in all Expressed in all testis: 56.0 Expressed in all +SRRM4 KIAA1853, nSR100 ENSG00000139767 Serine/arginine repetitive matrix 4 12 118981495-119163051 Predicted intracellular proteins Evidence at protein level HPA052783 Uncertain Tissue enriched Tissue enriched 9 cerebral cortex: 13.5 adrenal gland: 1.5 Group enriched 5 HeLa: 2.3;SCLC-21H: 4.6;SH-SY5Y: 3.3 +METTL21C C13orf39, LOC196541 ENSG00000139780 Methyltransferase like 21C 13 102685744-102694504 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 13 epididymis: 42.2 seminal vesicle: 3.1 Not detected +MBNL2 MBLL, MBLL39 ENSG00000139793 Muscleblind like splicing regulator 2 13 97221434-97394120 Predicted intracellular proteins Evidence at protein level HPA062685 Supported Nucleoplasm Pancreatic cancer:1.99e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 84.1 Mixed +RNF113B RNF161, ZNF183L1 ENSG00000139797 Ring finger protein 113B 13 98175785-98177265 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 588 testis: 58.8 all non-specific tissues: 0.0 Not detected +ZIC5 ENSG00000139800 Zic family member 5 13 99962964-99971909 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA074045 Uncertain Nucleoplasm
Vesicles Mixed Group enriched 45 cerebral cortex: 2.3;testis: 6.6 all non-specific tissues: 0.0 Cell line enhanced AF22: 21.7;NTERA-2: 15.0;SCLC-21H: 100.6 +ABHD13 bA153I24.2, BEM46L1, C13orf6, FLJ14906 ENSG00000139826 Abhydrolase domain containing 13 13 108218379-108234255 Predicted membrane proteins Evidence at protein level HPA032143, HPA032144 Approved Approved Cytosol Expressed in all Mixed thyroid gland: 12.7 Expressed in all +RAB20 FLJ20429 ENSG00000139832 RAB20, member RAS oncogene family 13 110523066-110561733 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052111, HPA068647 Uncertain Supported Golgi apparatus
Vesicles Urothelial cancer:4.48e-4 (favourable), Renal cancer:8.57e-4 (favourable) Expressed in all Mixed spleen: 42.0 Cell line enhanced SK-BR-3: 63.7;T-47d: 50.6 +GRTP1 FLJ22474, TBC1D6 ENSG00000139835 Growth hormone regulated TBC protein 1 13 113324164-113364148 Predicted intracellular proteins Evidence at protein level HPA046201 Approved Renal cancer:1.50e-5 (favourable) Expressed in all Expressed in all duodenum: 47.1 Cell line enhanced T-47d: 52.1 +CUL4A ENSG00000139842 Cullin 4A 13 113208193-113267108 Predicted intracellular proteins Evidence at protein level HPA058979 Approved Nucleoplasm Stomach cancer:2.84e-4 (favourable) Expressed in all Expressed in all testis: 90.1 Expressed in all +TTC6 C14orf25, NCRNA00291 ENSG00000139865 Tetratricopeptide repeat domain 6 14 37595847-38041442 Predicted intracellular proteins Evidence at protein level HPA069293 Approved Centrosome Group enriched Group enriched 6 breast: 10.5;prostate: 28.3;testis: 10.4 stomach: 2.6 Cell line enhanced Hep G2: 5.7;MCF7: 9.4;RT4: 6.7;T-47d: 21.4 +SSTR1 ENSG00000139874 Somatostatin receptor 1 14 38207999-38213067 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA031506 Approved Renal cancer:4.28e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 13.6;duodenum: 14.2;stomach: 21.4 small intestine: 9.1 Cell line enhanced BJ: 102.5;BJ hTERT+: 27.1;fHDF/TERT166: 56.0 +CDH24 CDH11L ENSG00000139880 Cadherin 24 14 23047062-23057538 Predicted membrane proteins Evidence at protein level HPA065233 Approved Nucleoplasm
Cell Junctions
Microtubule organizing center
Cytosol Renal cancer:1.15e-4 (unfavourable) Expressed in all Mixed endometrium: 8.5 Cell line enhanced SCLC-21H: 62.2 +REM2 FLJ38964 ENSG00000139890 RRAD and GEM like GTPase 2 14 22883165-22887686 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced bone marrow: 6.0;parathyroid gland: 4.6 testis: 2.9 Cell line enhanced AF22: 3.0 +CBLN3 ENSG00000139899 Cerebellin 3 precursor 14 24426532-24430954 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041266 Supported Supported Approved Nucleus Renal cancer:6.20e-6 (unfavourable), Endometrial cancer:4.22e-4 (unfavourable) Expressed in all Mixed spleen: 17.4 Cell line enhanced HDLM-2: 16.0;HSkMC: 17.3;Karpas-707: 13.3 +TSSK4 C14orf20, STK22E ENSG00000139908 Testis specific serine kinase 4 14 24205697-24208362 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060660, HPA077103 Enhanced Approved Cell Junctions Mixed Tissue enhanced testis: 42.2 skin: 10.1 Mixed +NOVA1 ENSG00000139910 NOVA alternative splicing regulator 1 14 26443093-26597754 Predicted intracellular proteins Evidence at protein level HPA004155 Uncertain Supported Nucleus
Nucleoli Tissue enriched Tissue enhanced cerebral cortex: 62.2 breast: 31.8 Cell line enhanced AF22: 40.2;HAP1: 20.8 +FITM1 FIT1 ENSG00000139914 Fat storage inducing transmembrane protein 1 14 24131275-24132849 Predicted membrane proteins Evidence at protein level HPA019842 Uncertain Liver cancer:1.00e-3 (favourable) Mixed Group enriched 15 heart muscle: 45.8;skeletal muscle: 113.0 spleen: 5.4 Cell line enriched 23 RH-30: 60.8 +MDGA2 MAMDC1 ENSG00000139915 MAM domain containing glycosylphosphatidylinositol anchor 2 14 46839629-47674954 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003084 Uncertain Tissue enhanced Group enriched 15 cerebral cortex: 6.2;testis: 6.9 skin: 0.4 Cell line enhanced AF22: 5.0;T-47d: 2.4;U-138 MG: 5.6;U-2 OS: 4.3;WM-115: 3.4 +TMX1 PDIA11, TMX, TXNDC, TXNDC1 ENSG00000139921 Thioredoxin related transmembrane protein 1 14 51240162-51257546 Predicted membrane proteins Evidence at protein level HPA003085 Approved Supported Nucleoli
Endoplasmic reticulum Liver cancer:1.29e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 19.8 Expressed in all +FRMD6 C14orf31, EX1, MGC17921, willin ENSG00000139926 FERM domain containing 6 14 51489100-51730727 Predicted intracellular proteins Evidence at protein level HPA001297 Uncertain Approved Approved Mitochondria Renal cancer:1.28e-4 (unfavourable), Pancreatic cancer:2.66e-4 (unfavourable), Stomach cancer:3.50e-4 (unfavourable) Expressed in all Mixed endometrium: 126.3 Cell line enhanced fHDF/TERT166: 644.4 +PELI2 ENSG00000139946 Pellino E3 ubiquitin protein ligase family member 2 14 56117814-56301526 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053182 Uncertain Approved Nucleus
Nucleoli
Intermediate filaments Renal cancer:1.53e-6 (favourable) Mixed Mixed testis: 18.8 Cell line enhanced HMC-1: 29.1;MOLT-4: 31.6;SCLC-21H: 20.6 +RTN1 NSP ENSG00000139970 Reticulon 1 14 59595976-59870966 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002745, HPA040945, HPA044249 Enhanced Enhanced Endoplasmic reticulum Pancreatic cancer:3.69e-4 (favourable) Tissue enhanced Tissue enriched 8 cerebral cortex: 411.6 parathyroid gland: 49.6 Cell line enhanced HEL: 54.3;SCLC-21H: 84.4;SH-SY5Y: 121.8 +C14orf37 UT2 ENSG00000139971 Chromosome 14 open reading frame 37 14 57999735-58298139 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001580, HPA001789 Enhanced Approved Plasma membrane Mixed Mixed kidney: 8.8 Cell line enhanced AF22: 9.6;fHDF/TERT166: 8.4 +SYT16 CHR14SYT, Strep14, SYT14L, yt14r ENSG00000139973 Synaptotagmin 16 14 61811974-62112550 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004199, HPA076871 Uncertain Approved Cytosol Mixed Group enriched 8 cerebral cortex: 18.0;prostate: 3.6;testis: 6.9 stomach: 1.2 Cell line enhanced A-431: 9.4;PC-3: 5.0;RPTEC TERT1: 4.7;RT4: 13.5;U-2 OS: 6.9 +SLC38A6 NAT-1 ENSG00000139974 Solute carrier family 38 member 6 14 60981114-61083733 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018508 Approved Approved Plasma membrane
Cell Junctions
Microtubules Liver cancer:9.47e-6 (unfavourable), Renal cancer:1.37e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 24.7 Mixed +NAA30 C14orf35, FLJ35355, MAK3, Mak3p, NAT12 ENSG00000139977 N(alpha)-acetyltransferase 30, NatC catalytic subunit 14 57390544-57415917 Enzymes, Predicted intracellular proteins Evidence at protein level HPA057824 Uncertain Supported Cytosol Renal cancer:1.25e-8 (favourable) Expressed in all Expressed in all testis: 34.2 Expressed in all +ADAM21 ADAM31 ENSG00000139985 ADAM metallopeptidase domain 21 14 70452157-70459899 Predicted membrane proteins Evidence at protein level HPA059016 Uncertain Not detected Tissue enriched 31 testis: 15.5 cerebral cortex: 0.5 Cell line enhanced U-138 MG: 1.4;U-251 MG: 1.1 +RDH12 FLJ30273, LCA13, RP53, SDR7C2 ENSG00000139988 Retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 14 67701886-67734452 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced gallbladder: 27.7;skin: 58.2 kidney: 13.6 Not detected +DCAF5 BCRG2, BCRP2, D14S1461E, KIAA1824, WDR22 ENSG00000139990 DDB1 and CUL4 associated factor 5 14 69050881-69153150 Predicted intracellular proteins Evidence at protein level HPA041575, HPA048098 Uncertain Approved Mitochondria Expressed in all Expressed in all testis: 111.5 Expressed in all +RAB15 ENSG00000139998 RAB15, member RAS oncogene family 14 64945814-64972776 Predicted intracellular proteins Evidence at protein level HPA041177 Uncertain Approved Vesicles
Microtubule organizing center Liver cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 62.9 Cell line enhanced HAP1: 153.9;RH-30: 186.0;RT4: 173.7 +WDR89 C14orf150, MGC9907 ENSG00000140006 WD repeat domain 89 14 63597039-63641861 Predicted intracellular proteins Evidence at protein level HPA000813 Uncertain Approved Intermediate filaments
Cytosol Liver cancer:3.26e-4 (unfavourable), Breast cancer:3.37e-4 (favourable) Expressed in all Expressed in all thyroid gland: 20.6 Expressed in all +ESR2 Erb, NR3A2 ENSG00000140009 Estrogen receptor 2 14 64084232-64338112 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB065126 Enhanced Not detected Tissue enhanced testis: 10.4 adrenal gland: 6.3 Cell line enhanced U-266/70: 7.3;U-698: 11.3 +KCNH5 eag2, H-EAG2, Kv10.2 ENSG00000140015 Potassium voltage-gated channel subfamily H member 5 14 62699454-63102037 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA030487 Uncertain Uncertain Microtubules
Mitotic spindle Not detected Tissue enhanced adrenal gland: 1.4;cerebral cortex: 3.6 testis: 0.7 Cell line enhanced BEWO: 1.5;HeLa: 5.0;RT4: 7.9 +STON2 STN2, STNB2 ENSG00000140022 Stonin 2 14 81260656-81436465 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003086 Enhanced Supported Nucleoli
Cytosol Endometrial cancer:4.96e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 34.2 Cell line enhanced HEL: 130.5;HMC-1: 63.9 +EFCAB11 C14orf143 ENSG00000140025 EF-hand calcium binding domain 11 14 89794669-89954777 Predicted intracellular proteins Evidence at transcript level HPA051209 Approved Cell Junctions
Cytosol Expressed in all Tissue enhanced testis: 60.1 fallopian tube: 17.2 Expressed in all +GPR65 hTDAG8, TDAG8 ENSG00000140030 G protein-coupled receptor 65 14 88005124-88014811 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA054454 Approved Cytosol Renal cancer:4.99e-4 (unfavourable) Mixed Mixed spleen: 13.3 Cell line enhanced Daudi: 4.0;HEL: 5.5;HL-60: 5.9;HMC-1: 7.9;RH-30: 11.1 +PTGR2 FLJ39091, ZADH1 ENSG00000140043 Prostaglandin reductase 2 14 73851844-73886827 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001125 Approved Approved Vesicles Renal cancer:4.55e-12 (favourable) Expressed in all Mixed thyroid gland: 21.2 Cell line enhanced T-47d: 39.4 +JDP2 JUNDM2 ENSG00000140044 Jun dimerization protein 2 14 75427716-75474111 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059511 Supported Approved Nucleoplasm
Nuclear speckles Colorectal cancer:8.58e-5 (unfavourable) Expressed in all Expressed in all spleen: 85.7 Cell line enhanced HHSteC: 140.4 +AK7 FLJ32864 ENSG00000140057 Adenylate kinase 7 14 96392111-96489427 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003543 Enhanced Renal cancer:1.14e-4 (favourable), Endometrial cancer:3.18e-4 (favourable) Mixed Tissue enhanced fallopian tube: 38.8 parathyroid gland: 14.9 Cell line enhanced BEWO: 16.6;CAPAN-2: 13.2;MCF7: 37.9;REH: 32.2 +FAM181A C14orf152 ENSG00000140067 Family with sequence similarity 181 member A 14 93918894-93929608 Predicted intracellular proteins Evidence at protein level HPA001603 Enhanced Group enriched Tissue enhanced cerebral cortex: 3.4;testis: 13.7 fallopian tube: 2.9 Cell line enriched 10 AF22: 4.2 +SLC24A4 NCKX4 ENSG00000140090 Solute carrier family 24 member 4 14 92322581-92501483 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Group enriched Tissue enhanced cerebral cortex: 7.1 spleen: 2.7 Cell line enhanced SCLC-21H: 1.5 +FBLN5 ARMD3, DANCE, EVEC, UP50 ENSG00000140092 Fibulin 5 14 91869412-91947987 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA000848, HPA000868, CAB025843 Supported Supported Plasma membrane Liver cancer:6.75e-4 (favourable) Expressed in all Expressed in all gallbladder: 221.0 Group enriched 6 ASC diff: 345.3;ASC TERT1: 182.9;BJ: 207.7;BJ hTERT+: 185.8;fHDF/TERT166: 343.2;HHSteC: 70.5;HSkMC: 175.5 +SERPINA10 PZI, ZPI ENSG00000140093 Serpin family A member 10 14 94280455-94293271 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA048739 Approved Nucleoplasm
Cytosol Liver cancer:9.00e-4 (favourable) Tissue enriched Tissue enriched 89 liver: 193.7 bone marrow: 2.1 Cell line enriched 6 Hep G2: 13.4 +C14orf79 ENSG00000140104 Chromosome 14 open reading frame 79 14 104985775-105010482 Predicted intracellular proteins Evidence at transcript level HPA042052, HPA061117 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Mixed fallopian tube: 24.1 Mixed +WARS IFI53, IFP53 ENSG00000140105 Tryptophanyl-tRNA synthetase 14 100333788-100376805 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005573, HPA018944 Enhanced Cytosol Ovarian cancer:1.94e-4 (favourable), Liver cancer:7.88e-4 (unfavourable) Expressed in all Expressed in all placenta: 473.2 Expressed in all +SLC25A47 C14orf68 ENSG00000140107 Solute carrier family 25 member 47 14 100323337-100330378 Predicted membrane proteins, Transporters Evidence at transcript level Tissue enriched Tissue enriched 171 liver: 101.0 duodenum,small intestine: 0.5 Cell line enhanced Hep G2: 1.1 +WDR20 DMR, FLJ33659, MGC33177 ENSG00000140153 WD repeat domain 20 14 102139503-102224847 Predicted intracellular proteins Evidence at protein level Renal cancer:3.26e-9 (favourable) Expressed in all Expressed in all testis: 40.6 Expressed in all +NIPA2 ENSG00000140157 Non imprinted in Prader-Willi/Angelman syndrome 2 15 22838641-22868384 Predicted membrane proteins, Transporters Evidence at protein level HPA067160, HPA071342 Approved Approved Golgi apparatus Expressed in all Expressed in all appendix: 44.4 Expressed in all +SLC12A6 ACCPN, KCC3 ENSG00000140199 Solute carrier family 12 member 6 15 34229996-34338060 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA034563 Uncertain Approved Vesicles
Cytosol Renal cancer:3.33e-6 (favourable) Expressed in all Mixed testis: 46.4 Cell line enhanced HaCaT: 38.6 +DUOXA1 FLJ32334, mol, NIP, NUMBIP ENSG00000140254 Dual oxidase maturation factor 1 15 45117367-45129938 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041578 Approved Tissue enhanced Tissue enhanced esophagus: 122.2;skin: 107.9;thyroid gland: 112.0 epididymis: 60.3 Cell line enriched 9 HaCaT: 92.0 +MFAP1 ENSG00000140259 Microfibrillar associated protein 1 15 43804492-43824802 Predicted intracellular proteins Evidence at protein level HPA042370 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.04e-9 (favourable), Liver cancer:2.50e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.2 Expressed in all +TCF12 bHLHb20, HEB, HsT17266, HTF4 ENSG00000140262 Transcription factor 12 15 56918623-57299281 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level CAB004432, HPA065827 Approved Supported Nucleoplasm
Nuclear speckles Renal cancer:5.24e-5 (unfavourable), Melanoma:8.89e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 116.2 Expressed in all +SORD ENSG00000140263 Sorbitol dehydrogenase 15 45023104-45077185 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040260, HPA040621 Enhanced Approved Cytosol Liver cancer:6.14e-5 (favourable) Expressed in all Expressed in all cervix, uterine: 404.7 Mixed +SERF2 4F5REL, FAM2C, H4F5rel, HsT17089 ENSG00000140264 Small EDRK-rich factor 2 15 43777087-43802589 Predicted intracellular proteins Evidence at protein level HPA056613 Uncertain Nucleus
Nucleoli Endometrial cancer:5.33e-4 (favourable) Expressed in all Expressed in all epididymis: 911.3 Expressed in all +ZSCAN29 FLJ35867, Zfp690, ZNF690 ENSG00000140265 Zinc finger and SCAN domain containing 29 15 43358172-43371025 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA007241, HPA011109 Enhanced Approved Nucleoplasm
Plasma membrane
Actin filaments Expressed in all Expressed in all testis: 27.3 Expressed in all +DUOXA2 ENSG00000140274 Dual oxidase maturation factor 2 15 45114321-45118421 Disease related genes, Predicted membrane proteins Evidence at protein level HPA063548 Enhanced Group enriched Tissue enhanced gallbladder: 97.3;urinary bladder: 24.7 thyroid gland: 13.6 Cell line enhanced U-2 OS: 1.0 +DUOX2 LNOX2, P138-TOX, P138(TOX), THOX2 ENSG00000140279 Dual oxidase 2 15 45092650-45114344 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Tissue enhanced Tissue enhanced gallbladder: 446.7;thyroid gland: 124.8 urinary bladder: 87.1 Cell line enriched 8 HaCaT: 5.5 +LYSMD2 MGC35274 ENSG00000140280 LysM domain containing 2 15 51723011-51751585 Predicted intracellular proteins Evidence at protein level HPA040460 Approved Approved Nuclear bodies
Mitochondria Expressed in all Expressed in all cerebral cortex: 38.2 Mixed +SLC27A2 ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS ENSG00000140284 Solute carrier family 27 member 2 15 50182196-50236395 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level HPA026089 Enhanced Renal cancer:7.48e-6 (favourable), Urothelial cancer:6.40e-4 (favourable) Tissue enhanced Group enriched 5 epididymis: 80.1;kidney: 162.3;liver: 145.5 placenta: 24.7 Cell line enhanced HaCaT: 78.4;HL-60: 52.3;SCLC-21H: 47.4 +FGF7 KGF ENSG00000140285 Fibroblast growth factor 7 15 49423096-49488775 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA043605 Uncertain Approved Nucleus
Nucleoli Mixed Tissue enhanced gallbladder: 55.0 endometrium: 31.1 Cell line enhanced ASC diff: 31.5;ASC TERT1: 29.3;HSkMC: 31.1;RH-30: 33.7;U-138 MG: 23.1 +HDC ENSG00000140287 Histidine decarboxylase 15 50241947-50266026 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038891 Approved Mixed Tissue enhanced epididymis: 53.2 gallbladder: 17.3 Group enriched 6 HEL: 392.3;HMC-1: 885.1 +GCNT3 C2/4GnT, C2GnT-M, C2GnT2 ENSG00000140297 Glucosaminyl (N-acetyl) transferase 3, mucin type 15 59594875-59640239 Enzymes, Predicted membrane proteins Evidence at protein level HPA011154 Enhanced Approved Golgi apparatus
Vesicles Liver cancer:6.49e-5 (unfavourable), Endometrial cancer:1.78e-4 (favourable) Tissue enhanced Tissue enhanced colon: 142.2;gallbladder: 118.0;rectum: 134.6;small intestine: 138.4 duodenum: 97.7 Cell line enriched 6 A549: 133.3 +BNIP2 BNIP-2, Nip2 ENSG00000140299 BCL2 interacting protein 2 15 59659146-59689534 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026843 Approved Renal cancer:2.19e-5 (unfavourable), Endometrial cancer:8.42e-4 (favourable) Expressed in all Expressed in all bone marrow: 84.4 Expressed in all +GTF2A2 HsT18745, TFIIA ENSG00000140307 General transcription factor IIA subunit 2 15 59638062-59657541 Predicted intracellular proteins Evidence at protein level HPA056239 Supported Nucleoplasm Expressed in all Tissue enriched 5 testis: 369.2 adrenal gland: 73.5 Expressed in all +SRP14 ALURBP, MGC14326 ENSG00000140319 Signal recognition particle 14 15 40035739-40039188 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA053738, HPA065118 Enhanced Nucleus
Nucleoli Renal cancer:5.31e-4 (favourable) Expressed in all Expressed in all thyroid gland: 373.9 Expressed in all +BAHD1 KIAA0945 ENSG00000140320 Bromo adjacent homology domain containing 1 15 40439721-40468242 Predicted intracellular proteins Evidence at protein level HPA041196 Supported Nucleoplasm Renal cancer:1.29e-10 (favourable), Breast cancer:1.55e-4 (unfavourable) Expressed in all Expressed in all testis: 27.3 Expressed in all +DISP2 C15orf36, DISPB, HsT16908, KIAA1742, LINC00594 ENSG00000140323 Dispatched RND transporter family member 2 15 40358235-40378639 Predicted membrane proteins Evidence at protein level HPA059903 Uncertain Approved Nucleoplasm
Vesicles Mixed Tissue enhanced cerebral cortex: 7.4 thyroid gland: 1.8 Group enriched 5 HaCaT: 5.9;SCLC-21H: 15.8 +CDAN1 CDA-I, CDAI ENSG00000140326 Codanin 1 15 42723559-42737126 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039404, HPA040787 Enhanced Enhanced Plasma membrane
Cytosol Liver cancer:1.07e-4 (unfavourable) Expressed in all Expressed in all ovary: 15.2 Expressed in all +TLE3 ESG, ESG3, GRG3, HsT18976, KIAA1547 ENSG00000140332 Transducin like enhancer of split 3 15 70047790-70098176 Predicted intracellular proteins Evidence at protein level HPA054116 Approved Supported Nucleoplasm Cervical cancer:2.09e-5 (favourable) Expressed in all Mixed bone marrow: 48.7 Expressed in all +ANP32A C15orf1, I1PP2A, LANP, MAPM, mapmodulin, PHAPI, PP32 ENSG00000140350 Acidic nuclear phosphoprotein 32 family member A 15 68778535-68820897 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005231, HPA063133, HPA067561 Supported Enhanced Nucleoplasm
Centrosome
Cytosol Expressed in all Expressed in all lymph node: 181.3 Expressed in all +COMMD4 FLJ20452 ENSG00000140365 COMM domain containing 4 15 75335891-75343224 Predicted intracellular proteins Evidence at protein level HPA066957 Uncertain Supported Nucleus
Plasma membrane Expressed in all Expressed in all testis: 76.2 Expressed in all +UBE2Q2 DKFZp762C143 ENSG00000140367 Ubiquitin conjugating enzyme E2 Q2 15 75843285-75901078 Enzymes, Predicted intracellular proteins Evidence at protein level Ovarian cancer:5.73e-4 (favourable) Expressed in all Expressed in all thyroid gland: 51.5 Expressed in all +PSTPIP1 CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP ENSG00000140368 Proline-serine-threonine phosphatase interacting protein 1 15 76993359-77037332 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA010600 Enhanced Renal cancer:7.36e-9 (unfavourable), Endometrial cancer:4.74e-5 (favourable) Expressed in all Tissue enhanced bone marrow: 37.6 appendix: 16.2 Cell line enhanced HDLM-2: 55.7;NB-4: 15.1;U-937: 50.2 +ETFA EMA, GA2, MADD ENSG00000140374 Electron transfer flavoprotein alpha subunit 15 76215355-76311472 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018990, HPA018993, HPA018996, HPA024089 Enhanced Enhanced Mitochondria Renal cancer:5.04e-8 (favourable) Expressed in all Expressed in all liver: 197.8 Expressed in all +BCL2A1 ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1 ENSG00000140379 BCL2 related protein A1 15 79960889-79971446 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:2.77e-5 (unfavourable) Expressed in all Tissue enhanced appendix: 115.2;bone marrow: 277.0 lymph node: 62.1 Cell line enhanced HMC-1: 76.7;SK-MEL-30: 329.3;U-138 MG: 43.6 +HMG20A FLJ10739, HMGX1, HMGXB1 ENSG00000140382 High mobility group 20A 15 77420412-77485607 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008126 Supported Approved Nucleus Expressed in all Expressed in all spleen: 49.0 Expressed in all +SCAPER Zfp291, ZNF291 ENSG00000140386 S-phase cyclin A associated protein in the ER 15 76347904-76905444 Predicted intracellular proteins Evidence at protein level HPA046253, HPA061180 Approved Supported Nucleus
Cytosol Renal cancer:2.69e-9 (favourable) Expressed in all Expressed in all testis: 38.4 Expressed in all +TSPAN3 TM4-A, TM4SF8, TSPAN-3 ENSG00000140391 Tetraspanin 3 15 77041404-77083984 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA015996 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all Expressed in all epididymis: 527.2 Expressed in all +WDR61 REC14 ENSG00000140395 WD repeat domain 61 15 78277835-78299794 Predicted intracellular proteins Evidence at protein level HPA039932, HPA040065 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:2.03e-10 (favourable) Expressed in all Expressed in all epididymis: 126.8 Expressed in all +NCOA2 bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2 ENSG00000140396 Nuclear receptor coactivator 2 8 70109762-70403805 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060243 Supported Nucleoplasm
Nuclear bodies Renal cancer:5.08e-4 (favourable) Expressed in all Expressed in all epididymis: 36.0 Expressed in all +NEIL1 FLJ22402, FPG1, hFPG1, NEI1 ENSG00000140398 Nei like DNA glycosylase 1 15 75346955-75357114 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054084 Approved Supported Nucleoplasm Pancreatic cancer:2.09e-4 (favourable) Expressed in all Expressed in all adrenal gland: 10.6 Mixed +MAN2C1 MANA, MANA1 ENSG00000140400 Mannosidase alpha class 2C member 1 15 75355207-75368630 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040627, HPA067407 Uncertain Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 46.7 Expressed in all +DNAJA4 PRO1472 ENSG00000140403 DnaJ heat shock protein family (Hsp40) member A4 15 78264086-78282196 Predicted intracellular proteins Evidence at protein level CAB004646, HPA041790 Uncertain Approved Plasma membrane
Cytosol Renal cancer:1.08e-7 (favourable), Glioma:8.35e-4 (unfavourable) Expressed in all Expressed in all testis: 95.4 Cell line enhanced CAPAN-2: 38.0;RT4: 67.8;SCLC-21H: 62.7;SiHa: 45.2 +MESDC1 MGC99595 ENSG00000140406 Mesoderm development candidate 1 15 81000944-81005788 Predicted intracellular proteins Evidence at protein level HPA071716 Approved Nucleoplasm
Cytoplasmic bodies Renal cancer:1.87e-7 (unfavourable), Lung cancer:1.47e-5 (unfavourable) Expressed in all Mixed spleen: 14.3 Expressed in all +TPM1 C15orf13, CMH3 ENSG00000140416 Tropomyosin 1 (alpha) 15 63042632-63071915 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000261, HPA009066, CAB017698, HPA047089, HPA053624 Supported Approved Actin filaments
Cytosol Urothelial cancer:7.30e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 7139.0 Expressed in all +IGF1R CD221, IGFIR, IGFR, JTK13, MGC18216 ENSG00000140443 Insulin like growth factor 1 receptor 15 98648971-98964530 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level CAB010268, HPA045563 Uncertain Uncertain Vesicles Renal cancer:3.75e-7 (favourable) Expressed in all Mixed prostate: 25.0 Mixed +ARRDC4 FLJ36045 ENSG00000140450 Arrestin domain containing 4 15 97960698-97973838 Predicted intracellular proteins Evidence at protein level HPA042109 Approved Expressed in all Expressed in all skin: 42.0 Cell line enhanced BJ: 86.9;hTCEpi: 62.8 +PIF1 C15orf20, FLJ22692 ENSG00000140451 PIF1 5'-to-3' DNA helicase 15 64815632-64825668 Enzymes, Predicted intracellular proteins Evidence at protein level CAB018701 Supported Supported Nucleoplasm Melanoma:5.22e-4 (unfavourable) Tissue enhanced Mixed lymph node: 5.3 Mixed +USP3 ENSG00000140455 Ubiquitin specific peptidase 3 15 63504511-63594640 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053275, HPA060513, HPA077975 Supported Nucleoplasm Urothelial cancer:1.38e-4 (favourable) Expressed in all Expressed in all bone marrow: 32.1 Expressed in all +CYP11A1 CYP11A, P450SCC ENSG00000140459 Cytochrome P450 family 11 subfamily A member 1 15 74337759-74367740 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA016436 Enhanced Mixed Tissue enriched 11 adrenal gland: 748.5 testis: 68.5 Group enriched 25 BEWO: 102.7;HEL: 79.0;SiHa: 23.2 +BBS4 ENSG00000140463 Bardet-Biedl syndrome 4 15 72686179-72738476 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039418 Approved Supported Cytosol Endometrial cancer:2.57e-4 (favourable) Expressed in all Expressed in all testis: 37.0 Expressed in all +PML MYL, RNF71, TRIM19 ENSG00000140464 Promyelocytic leukemia 15 73994673-74047812 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008312, CAB010194, CAB016304 Supported Enhanced Nuclear bodies Renal cancer:6.27e-8 (unfavourable), Breast cancer:3.24e-4 (favourable), Pancreatic cancer:3.29e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 45.1 Expressed in all +CYP1A1 CP11, CYP1, P1-450, P450-C, P450DX ENSG00000140465 Cytochrome P450 family 1 subfamily A member 1 15 74719542-74725610 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB018654 Uncertain Group enriched Group enriched 8 liver: 33.9;small intestine: 20.5;urinary bladder: 80.8 breast: 5.7 Cell line enhanced CACO-2: 30.3;hTCEpi: 14.0;HUVEC TERT2: 15.7 +ADAMTS17 FLJ16363, FLJ32769 ENSG00000140470 ADAM metallopeptidase with thrombospondin type 1 motif 17 15 99971589-100342005 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA062487 Approved Nucleus Mixed Mixed endometrium: 3.4 Cell line enhanced HEK 293: 8.0;SK-MEL-30: 3.4;WM-115: 4.0 +LINS1 LINS, WINS1 ENSG00000140471 Lines homolog 1 15 100559369-100603230 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038578, HPA038579 Approved Approved Nucleoplasm Expressed in all Expressed in all thyroid gland: 14.0 Expressed in all +ULK3 DKFZP434C131, FLJ90566 ENSG00000140474 Unc-51 like kinase 3 15 74836116-74843346 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040474 Approved Pancreatic cancer:7.47e-4 (favourable) Expressed in all Expressed in all esophagus: 28.4 Expressed in all +GOLGA6D ENSG00000140478 Golgin A6 family member D 15 75282835-75295807 Predicted intracellular proteins Evidence at protein level HPA044978, HPA050087 Supported Not detected Tissue enriched 16 testis: 17.8 liver: 1.1 Not detected +PCSK6 PACE4, SPC4 ENSG00000140479 Proprotein convertase subtilisin/kexin type 6 15 101297142-101525202 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004774 Uncertain Renal cancer:7.06e-7 (unfavourable), Breast cancer:9.99e-4 (favourable) Mixed Tissue enhanced liver: 90.3;spleen: 124.6 placenta: 53.9 Cell line enhanced BEWO: 57.8;HEK 293: 58.5;Hep G2: 39.9 +CCDC33 CT61, FLJ32855 ENSG00000140481 Coiled-coil domain containing 33 15 74202705-74336472 Plasma proteins, Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 17 fallopian tube: 75.4;testis: 22.5 lung: 2.8 Group enriched 5 CAPAN-2: 7.8;SCLC-21H: 5.8;SH-SY5Y: 6.3 +CELF6 BRUNOL6 ENSG00000140488 CUGBP Elav-like family member 6 15 72284727-72320129 Predicted intracellular proteins Evidence at protein level HPA046985, HPA053526 Uncertain Approved Cytosol Not detected Mixed cerebral cortex: 11.1 Cell line enhanced U-266/70: 2.7 +SCAMP2 ENSG00000140497 Secretory carrier membrane protein 2 15 74843730-74873365 Predicted membrane proteins Evidence at protein level HPA014699, HPA019194 Approved Supported Golgi apparatus
Vesicles Renal cancer:1.12e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 128.7 Expressed in all +CYP1A2 CP12, P3-450 ENSG00000140505 Cytochrome P450 family 1 subfamily A member 2 15 74748844-74756202 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level CAB016531 Enhanced Group enriched Tissue enriched 170 liver: 268.6 thyroid gland: 1.5 Mixed +LMAN1L ERGIC-53L, ERGL ENSG00000140506 Lectin, mannose binding 1 like 15 74812716-74825758 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enhanced prostate: 91.3;spleen: 31.7 heart muscle: 12.7 Not detected +HAPLN3 EXLD1, HsT19883 ENSG00000140511 Hyaluronan and proteoglycan link protein 3 15 88877288-88895626 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA039237 Uncertain Approved Plasma membrane
Cytosol Renal cancer:4.18e-13 (unfavourable) Expressed in all Tissue enhanced appendix: 13.8;lymph node: 10.8 spleen: 4.0 Cell line enhanced HDLM-2: 29.8;U-2 OS: 31.7 +RHCG C15orf6, PDRC2, RHGK, SLC42A3 ENSG00000140519 Rh family C glycoprotein 15 89471398-89496613 Predicted membrane proteins, Transporters Evidence at protein level HPA041874, HPA043317 Enhanced Lung cancer:3.80e-4 (unfavourable) Tissue enhanced Tissue enriched 7 esophagus: 2901.8 tonsil: 420.3 Cell line enhanced A549: 3.3;hTCEpi: 1.4;RT4: 1.6;SK-MEL-30: 1.0 +POLG POLG1, POLGA ENSG00000140521 DNA polymerase gamma, catalytic subunit 15 89305198-89334861 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA056821 Approved Prostate cancer:5.73e-4 (unfavourable) Expressed in all Expressed in all spleen: 19.7 Expressed in all +RLBP1 CRALBP ENSG00000140522 Retinaldehyde binding protein 1 15 89209869-89221751 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042051, HPA044083 Supported Approved Approved Nucleoplasm
Centrosome
Cytosol Group enriched Tissue enriched 9 cerebral cortex: 6.1 testis: 0.6 Cell line enriched 53 SK-MEL-30: 16.5 +FANCI FLJ10719, KIAA1794 ENSG00000140525 Fanconi anemia complementation group I 15 89243949-89317261 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039972, HPA040379 Approved Enhanced Nucleoplasm Renal cancer:2.71e-13 (unfavourable), Liver cancer:1.11e-4 (unfavourable), Pancreatic cancer:3.59e-4 (unfavourable) Expressed in all Tissue enhanced testis: 60.4 lymph node: 28.6 Expressed in all +ABHD2 LABH2 ENSG00000140526 Abhydrolase domain containing 2 15 89087459-89202360 Enzymes, Predicted membrane proteins Evidence at protein level HPA005999 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.18e-7 (favourable) Expressed in all Expressed in all testis: 93.8 Expressed in all +WDR93 ENSG00000140527 WD repeat domain 93 15 89690797-89743638 Predicted intracellular proteins Evidence at transcript level HPA046196, HPA048112 Uncertain Uncertain Actin filaments Mixed Tissue enhanced fallopian tube: 14.2;testis: 21.1 epididymis: 6.1 Mixed +TICRR C15orf42, FLJ41618, MGC45866, SLD3, Treslin ENSG00000140534 TOPBP1 interacting checkpoint and replication regulator 15 89575482-89631056 Predicted intracellular proteins Evidence at protein level HPA046746, HPA049454 Enhanced Nucleoplasm Melanoma:2.87e-6 (unfavourable), Endometrial cancer:4.44e-4 (unfavourable) Mixed Mixed testis: 2.7 Mixed +NTRK3 TRKC ENSG00000140538 Neurotrophic receptor tyrosine kinase 3 15 87859751-88256768 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009233, HPA027484, HPA048065 Enhanced Supported Nuclear membrane
Nucleoli Tissue enhanced Tissue enhanced cerebral cortex: 39.6 testis: 15.2 Cell line enriched 8 U-138 MG: 99.2 +DET1 FLJ10103 ENSG00000140543 De-etiolated homolog 1 (Arabidopsis) 15 88494440-88546675 Predicted intracellular proteins Evidence at protein level HPA048873 Uncertain Approved Nucleoplasm
Microtubules Expressed in all Mixed ovary: 14.1 Mixed +MFGE8 BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10 ENSG00000140545 Milk fat globule-EGF factor 8 protein 15 88898683-88913411 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB002753, HPA002807 Uncertain Approved Cytosol Renal cancer:6.06e-9 (unfavourable), Stomach cancer:3.08e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 319.8 Cell line enhanced ASC diff: 1212.9;ASC TERT1: 638.2;HSkMC: 676.6 +ZNF710 DKFZp547K1113, FLJ00306, FLJ37393 ENSG00000140548 Zinc finger protein 710 15 90001392-90082206 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030226, HPA030227, HPA030228 Enhanced Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all appendix: 20.4 Expressed in all +UNC45A GC-UNC45, SMAP-1 ENSG00000140553 Unc-45 myosin chaperone A 15 90930180-90954093 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039228 Approved Supported Nuclear speckles
Cytosol Renal cancer:7.46e-7 (favourable), Liver cancer:7.72e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.3 Expressed in all +ST8SIA2 HsT19690, SIAT8B, ST8SIA-II, STX ENSG00000140557 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 15 92393828-92468728 Predicted secreted proteins Evidence at protein level HPA054518 Approved Approved Microtubule organizing center Mixed Tissue enhanced cerebral cortex: 2.1;heart muscle: 2.4 cervix, uterine: 1.2 Cell line enhanced AF22: 25.4;LHCN-M2: 6.4;RH-30: 11.3;RPMI-8226: 6.1;WM-115: 7.1 +MCTP2 FLJ11175, FLJ33303 ENSG00000140563 Multiple C2 and transmembrane domain containing 2 15 94231538-94483952 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051176, HPA070541 Uncertain Enhanced Nucleoplasm
Cytosol Renal cancer:2.18e-5 (unfavourable) Mixed Mixed placenta: 28.6 Cell line enhanced HEL: 19.0;U-698: 15.8;U-87 MG: 24.4 +FURIN FUR, PACE, PCSK3, SPC1 ENSG00000140564 Furin, paired basic amino acid cleaving enzyme 15 90868592-90883458 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009499 Approved Supported Nucleoplasm
Golgi apparatus Lung cancer:1.58e-4 (unfavourable) Expressed in all Expressed in all salivary gland: 92.8 Expressed in all +IQGAP1 HUMORFA01, KIAA0051, p195, SAR1 ENSG00000140575 IQ motif containing GTPase activating protein 1 15 90388218-90502243 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013302, HPA014055 Enhanced Supported Plasma membrane
Cell Junctions Pancreatic cancer:5.67e-5 (unfavourable) Expressed in all Expressed in all endometrium: 120.4 Expressed in all +CRTC3 FLJ21868 ENSG00000140577 CREB regulated transcription coactivator 3 15 90529925-90645345 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA043735, HPA063691 Uncertain Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all ovary: 50.7 Mixed +EFL1 EFTUD1, FAM42A, FLJ13119, HsT19294, RIA1 ENSG00000140598 Elongation factor like GTPase 1 15 82130230-82262763 Predicted intracellular proteins Evidence at protein level HPA039654, HPA047110, HPA052345 Uncertain Approved Cytosol Renal cancer:1.50e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 23.4 Expressed in all +SH3GL3 CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13 ENSG00000140600 SH3 domain containing GRB2 like 3, endophilin A3 15 83447228-83618743 Predicted intracellular proteins Evidence at protein level HPA039381 Enhanced Mixed Group enriched 12 cerebral cortex: 29.9;testis: 38.5 lung: 2.9 Cell line enhanced HAP1: 30.3;HEK 293: 13.3;K-562: 21.4;RH-30: 8.7 +SEC11A SEC11L1, sid2895, SPC18, SPCS4A ENSG00000140612 SEC11 homolog A, signal peptidase complex subunit 15 84669538-84716716 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047533 Approved Nuclear membrane
Golgi apparatus Endometrial cancer:1.94e-5 (favourable), Head and neck cancer:5.99e-5 (unfavourable), Thyroid cancer:2.95e-4 (favourable) Expressed in all Expressed in all thyroid gland: 211.1 Expressed in all +SEPT12 FLJ25410 ENSG00000140623 Septin 12 16 4777669-4788521 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041128 Uncertain Microtubules Tissue enhanced Tissue enriched 668 testis: 107.9 bone marrow: 0.1 Not detected +GLYR1 BM045, HIBDL, N-PAC, NP60 ENSG00000140632 Glyoxylate reductase 1 homolog 16 4803203-4847342 Predicted intracellular proteins Evidence at protein level CAB017022, HPA048226, HPA050136 Enhanced Enhanced Nucleoplasm
Nuclear speckles Renal cancer:8.74e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 111.5 Expressed in all +PMM2 CDG1, CDG1a, CDGS, PMI, PMI1 ENSG00000140650 Phosphomannomutase 2 16 8788823-8849331 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA040852, HPA063649 Approved Approved Nucleus
Cytosol Renal cancer:8.97e-6 (unfavourable), Colorectal cancer:1.04e-4 (favourable) Expressed in all Expressed in all rectum: 28.3 Expressed in all +SLC5A2 SGLT2 ENSG00000140675 Solute carrier family 5 member 2 16 31483002-31490860 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA041603 Enhanced Not detected Tissue enriched 10 kidney: 26.5 testis: 2.7 Not detected +ITGAX CD11C ENSG00000140678 Integrin subunit alpha X 16 31355134-31382997 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004458, HPA004723, CAB072871 Enhanced Renal cancer:1.37e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 58.3;spleen: 59.0 bone marrow: 30.4 Cell line enriched 5 HMC-1: 92.2 +TGFB1I1 ARA55, Hic-5, TSC-5 ENSG00000140682 Transforming growth factor beta 1 induced transcript 1 16 31471585-31477960 Predicted intracellular proteins Evidence at protein level CAB020844 Enhanced Supported Focal adhesion sites
Cytosol Renal cancer:6.06e-8 (unfavourable), Urothelial cancer:7.73e-5 (unfavourable) Expressed in all Tissue enhanced endometrium: 137.4;smooth muscle: 150.3 seminal vesicle: 104.2 Mixed +C16orf58 FLJ13868 ENSG00000140688 Chromosome 16 open reading frame 58 16 31489471-31509309 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024406 Uncertain Approved Nucleoplasm
Nucleoli
Golgi apparatus
Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 77.4 Expressed in all +ARMC5 FLJ13063 ENSG00000140691 Armadillo repeat containing 5 16 31458080-31467166 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041524, HPA063706 Approved Approved Nucleoplasm
Focal adhesion sites
Cytosol Pancreatic cancer:1.97e-6 (favourable) Expressed in all Mixed bone marrow: 13.2 Cell line enhanced NB-4: 37.4 +PARN DAN ENSG00000140694 Poly(A)-specific ribonuclease 16 14435701-14632728 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006314, CAB011673, HPA012010 Enhanced Approved Nucleoli
Nuclear speckles Head and neck cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.0 Expressed in all +FTO ALKBH9, KIAA1752, MGC5149 ENSG00000140718 FTO, alpha-ketoglutarate dependent dioxygenase 16 53701692-54158512 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB017123, HPA041086, HPA068695 Enhanced Approved Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 87.0 Expressed in all +UQCRC2 QCR2, UQCR2 ENSG00000140740 Ubiquinol-cytochrome c reductase core protein II 16 21952660-21983660 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007998, HPA019146 Enhanced Enhanced Mitochondria Renal cancer:6.58e-9 (favourable) Expressed in all Expressed in all heart muscle: 151.1 Expressed in all +CDR2 CDR62, Yo ENSG00000140743 Cerebellar degeneration related protein 2 16 22345936-22437165 Predicted intracellular proteins Evidence at protein level HPA018151, HPA023870 Uncertain Approved Nucleoplasm Expressed in all Expressed in all testis: 108.5 Expressed in all +IGSF6 DORA ENSG00000140749 Immunoglobulin superfamily member 6 16 21639537-21652660 Predicted membrane proteins Evidence at protein level HPA041023, HPA041072 Uncertain Endometrial cancer:1.54e-5 (favourable), Cervical cancer:4.92e-4 (favourable) Expressed in all Tissue enhanced appendix: 15.2;spleen: 18.1 lung: 8.0 Not detected +ARHGAP17 FLJ10308, FLJ13219, NADRIN, RICH1, WBP15 ENSG00000140750 Rho GTPase activating protein 17 16 24919385-25015666 Predicted intracellular proteins Evidence at protein level HPA041703 Approved Approved Nucleus
Cytosol Endometrial cancer:3.59e-4 (favourable), Urothelial cancer:3.76e-4 (unfavourable), Liver cancer:4.95e-4 (unfavourable) Expressed in all Expressed in all spleen: 70.5 Mixed +MYLK3 caMLCK, MLCK ENSG00000140795 Myosin light chain kinase 3 16 46703369-46790407 Enzymes, Predicted membrane proteins Evidence at protein level HPA073447 Enhanced Not detected Tissue enhanced heart muscle: 69.4;skeletal muscle: 16.9 testis: 11.7 Cell line enhanced BEWO: 12.5;HEL: 36.3;K-562: 5.8;SK-BR-3: 6.2 +ABCC12 MRP9 ENSG00000140798 ATP binding cassette subfamily C member 12 16 48082973-48156018 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA043100 Uncertain Tissue enhanced Tissue enhanced testis: 2.9 breast: 0.6 Not detected +NKD1 ENSG00000140807 Naked cuticle homolog 1 16 50548330-50649249 Predicted intracellular proteins Evidence at protein level HPA041352, HPA049413 Uncertain Approved Nucleoli fibrillar center Tissue enhanced Mixed smooth muscle: 8.1 Group enriched 6 AF22: 6.2;CACO-2: 11.1;Hep G2: 24.6 +DHX38 DDX38, hPrp16, KIAA0224, PRP16, PRPF16 ENSG00000140829 DEAH-box helicase 38 16 72093562-72112912 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041347, HPA041604 Uncertain Supported Nucleus Expressed in all Expressed in all parathyroid gland: 50.0 Expressed in all +TXNL4B Dim2, DLP, FLJ20511 ENSG00000140830 Thioredoxin like 4B 16 72044289-72094431 Predicted intracellular proteins Evidence at protein level HPA065865 Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 28.8 Expressed in all +MARVELD3 MRVLDC3 ENSG00000140832 MARVEL domain containing 3 16 71626161-71642114 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA043514, HPA045471 Approved Vesicles
Intermediate filaments Renal cancer:6.80e-10 (favourable) Mixed Tissue enhanced small intestine: 37.1 duodenum: 31.5 Cell line enhanced BEWO: 29.9;CAPAN-2: 19.9;MCF7: 31.1;T-47d: 24.8 +CHST4 HEC-GLCNAC-6-ST, LSST ENSG00000140835 Carbohydrate sulfotransferase 4 16 71525233-71538746 Predicted secreted proteins Evidence at protein level HPA021955 Enhanced Liver cancer:9.24e-4 (unfavourable) Tissue enriched Tissue enriched 13 gallbladder: 102.5 fallopian tube: 8.0 Cell line enhanced CAPAN-2: 7.3;NB-4: 3.0;NTERA-2: 7.1;SCLC-21H: 4.0 +ZFHX3 ATBF1, ZNF927 ENSG00000140836 Zinc finger homeobox 3 16 72782885-73059698 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059353 Uncertain Renal cancer:1.37e-5 (favourable), Breast cancer:1.55e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 28.3 thyroid gland: 12.4 Mixed +CLEC18B ENSG00000140839 C-type lectin domain family 18 member B 16 74408270-74421953 Predicted secreted proteins Evidence at transcript level HPA048976 Uncertain Glioma:1.55e-4 (unfavourable) Group enriched Group enriched 10 kidney: 30.9;testis: 8.1 cerebral cortex: 2.0 Cell line enhanced AF22: 1.1;K-562: 2.7 +CPNE2 CPN2 ENSG00000140848 Copine 2 16 57092537-57148367 Predicted intracellular proteins Evidence at protein level HPA041132 Approved Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all Expressed in all lung: 55.6 Mixed +NLRC5 CLR16.1, FLJ21709, NOD27 ENSG00000140853 NLR family CARD domain containing 5 16 56989485-57083531 Predicted intracellular proteins Evidence at protein level HPA059120, HPA060405 Supported Centrosome Ovarian cancer:2.30e-4 (favourable), Renal cancer:2.44e-4 (unfavourable), Cervical cancer:9.69e-4 (favourable) Expressed in all Mixed spleen: 45.1 Cell line enhanced HEL: 84.3 +KATNB1 ENSG00000140854 Katanin regulatory subunit B1 16 57735730-57757250 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041165, HPA041839 Enhanced Supported Plasma membrane
Microtubules
Cytosol Liver cancer:3.93e-4 (unfavourable), Pancreatic cancer:8.44e-4 (favourable), Endometrial cancer:9.24e-4 (favourable) Expressed in all Expressed in all testis: 45.3 Expressed in all +KIFC3 ENSG00000140859 Kinesin family member C3 16 57758217-57863053 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA021240 Uncertain Expressed in all Expressed in all skin: 98.4 Expressed in all +ADAMTS18 ADAMTS21 ENSG00000140873 ADAM metallopeptidase with thrombospondin type 1 motif 18 16 77247813-77435114 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044326 Uncertain Mixed Tissue enriched 16 placenta: 29.1 cervix, uterine: 1.8 Group enriched 7 HUVEC TERT2: 6.7;TIME: 2.0;U-87 MG: 4.7 +NUDT7 ENSG00000140876 Nudix hydrolase 7 16 77722492-77742260 Predicted intracellular proteins Evidence at protein level HPA042042 Supported Approved Nucleoplasm
Golgi apparatus Renal cancer:5.36e-11 (favourable), Head and neck cancer:1.84e-4 (unfavourable) Expressed in all Expressed in all liver: 35.7 Cell line enhanced THP-1: 33.4 +GCSH ENSG00000140905 Glycine cleavage system protein H 16 81081938-81096425 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041368 Approved Approved Vesicles Renal cancer:6.26e-6 (favourable) Expressed in all Expressed in all thyroid gland: 157.3 Expressed in all +CMTM3 BNAS2, CKLFSF3, FLJ31762 ENSG00000140931 CKLF like MARVEL transmembrane domain containing 3 16 66603874-66613892 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013870, HPA072695 Approved Approved Nucleoplasm Renal cancer:4.42e-6 (unfavourable), Stomach cancer:1.85e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 69.6 Mixed +CMTM2 CKLFSF2, FLJ25732, MGC39436 ENSG00000140932 CKLF like MARVEL transmembrane domain containing 2 16 66579448-66588275 Predicted membrane proteins Evidence at transcript level Mixed Tissue enriched 1018 testis: 712.6 appendix,bone marrow: 0.6 Cell line enriched 23 REH: 29.0 +CDH11 CAD11, OB ENSG00000140937 Cadherin 11 16 64943753-65126112 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB013072 Enhanced Renal cancer:2.48e-9 (unfavourable) Expressed in all Tissue enhanced ovary: 223.4 placenta: 173.7 Cell line enhanced BJ: 205.7;fHDF/TERT166: 259.6;HSkMC: 159.5;PC-3: 262.9;U-2197: 178.5 +NOL3 ARC, CARD2, MYP, NOP30 ENSG00000140939 Nucleolar protein 3 16 67170154-67175735 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB009208 Enhanced Supported Nucleus
Cytosol Liver cancer:6.43e-5 (unfavourable), Renal cancer:2.41e-4 (unfavourable) Expressed in all Mixed skin: 69.2 Mixed +MAP1LC3B ATG8F ENSG00000140941 Microtubule associated protein 1 light chain 3 beta 16 87383995-87404779 Predicted intracellular proteins Evidence at protein level CAB037216, HPA052474, HPA052484, HPA053767 Uncertain Renal cancer:2.77e-7 (favourable), Stomach cancer:8.97e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 122.4 Expressed in all +MBTPS1 KIAA0091, PCSK8, S1P, SKI-1 ENSG00000140943 Membrane bound transcription factor peptidase, site 1 16 84053761-84116906 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA056109 Supported Renal cancer:2.21e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 118.5 Expressed in all +CDH13 CDHH ENSG00000140945 Cadherin 13 16 82626803-83800640 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001380, CAB025863 Enhanced Supported Plasma membrane Renal cancer:1.73e-6 (unfavourable) Expressed in all Tissue enhanced endometrium: 70.0 cervix, uterine: 66.4 Cell line enhanced LHCN-M2: 185.2;U-138 MG: 276.1;U-87 MG: 239.0 +ZCCHC14 BDG29, MGC14139 ENSG00000140948 Zinc finger CCHC-type containing 14 16 87406246-87492045 Predicted intracellular proteins Evidence at protein level HPA014122 Uncertain Nuclear membrane Renal cancer:1.47e-14 (favourable) Expressed in all Expressed in all testis: 61.6 Mixed +TLDC1 KIAA1609 ENSG00000140950 TBC/LysM-associated domain containing 1 16 84476421-84554033 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041020 Approved Approved Nucleus
Nucleoli
Cytosol Lung cancer:1.03e-5 (unfavourable), Pancreatic cancer:7.05e-5 (unfavourable) Expressed in all Mixed placenta: 15.5 Mixed +ADAD2 FLJ00337, TENRL ENSG00000140955 Adenosine deaminase domain containing 2 16 84191138-84197168 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 43 testis: 32.3 cerebral cortex,skin: 0.7 Cell line enriched 10 SCLC-21H: 3.2 +OSGIN1 BDGI, OKL38 ENSG00000140961 Oxidative stress induced growth inhibitor 1 16 83948282-83966332 Predicted intracellular proteins Evidence at protein level HPA019239 Approved Nucleoplasm
Cytosol Endometrial cancer:4.89e-5 (favourable) Tissue enriched Tissue enhanced liver: 57.3 duodenum: 31.3 Cell line enhanced A549: 60.9;Hep G2: 69.5;T-47d: 69.3;WM-115: 61.3 +IRF8 ICSBP, ICSBP1, IRF-8 ENSG00000140968 Interferon regulatory factor 8 16 85898803-85922609 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002267, HPA002531, CAB013480 Enhanced Enhanced Nucleoplasm Expressed in all Tissue enhanced lymph node: 297.7;spleen: 205.7;tonsil: 232.5 appendix: 118.0 Cell line enhanced Daudi: 177.0;THP-1: 280.9;U-698: 672.1;U-937: 108.3 +RHOT2 ARHT2, C16orf39, MIRO-2 ENSG00000140983 Ras homolog family member T2 16 668086-674174 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012624, HPA012895 Approved Supported Cytosol Head and neck cancer:5.01e-4 (favourable), Renal cancer:5.43e-4 (favourable) Expressed in all Expressed in all spleen: 31.2 Expressed in all +RPL3L ENSG00000140986 Ribosomal protein L3 like 16 1943974-1957606 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA049136 Enhanced Approved Nuclear speckles Mixed Tissue enriched 5 skeletal muscle: 323.9 heart muscle: 61.3 Cell line enhanced CACO-2: 3.3 +ZSCAN32 FLJ20417, ZNF434 ENSG00000140987 Zinc finger and SCAN domain containing 32 16 3382081-3401065 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005758 Uncertain Approved Nucleoplasm Mixed Expressed in all parathyroid gland: 13.6 Expressed in all +RPS2 LLREP3, S2 ENSG00000140988 Ribosomal protein S2 16 1962052-1964860 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055133 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:3.04e-7 (unfavourable), Liver cancer:7.70e-4 (unfavourable) Expressed in all Expressed in all ovary: 3063.2 Expressed in all +NDUFB10 PDSW ENSG00000140990 NADH:ubiquinone oxidoreductase subunit B10 16 1959508-1961975 Predicted intracellular proteins Evidence at protein level HPA073189 Enhanced Renal cancer:9.43e-6 (favourable), Cervical cancer:7.38e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 449.6 Expressed in all +PDPK1 PDK1 ENSG00000140992 3-phosphoinositide dependent protein kinase 1 16 2537964-2603188 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004272, HPA035199, HPA068961 Supported Approved Vesicles Renal cancer:1.29e-14 (favourable) Expressed in all Expressed in all parathyroid gland: 52.0 Expressed in all +TIGD7 Sancho ENSG00000140993 Tigger transposable element derived 7 16 3298832-3305729 Predicted intracellular proteins Evidence at protein level HPA041357, HPA041474 Uncertain Supported Plasma membrane
Cytosol Mixed Mixed parathyroid gland: 14.7 Mixed +DEF8 FLJ20186 ENSG00000140995 Differentially expressed in FDCP 8 homolog 16 89947925-89968060 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041745, HPA049434 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.95e-8 (favourable), Pancreatic cancer:1.35e-7 (favourable) Expressed in all Expressed in all lymph node: 89.1 Expressed in all +TCF25 KIAA1049, Nulp1 ENSG00000141002 Transcription factor 25 16 89873570-89913627 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041699, HPA041786 Enhanced Endometrial cancer:6.95e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 123.7 Expressed in all +GALNS GALNAC6S, GAS ENSG00000141012 Galactosamine (N-acetyl)-6-sulfatase 16 88813734-88856970 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026404, HPA042433 Enhanced Approved Cytosol Liver cancer:3.66e-4 (unfavourable) Expressed in all Expressed in all testis: 29.7 Expressed in all +GAS8 DRC4, GAS11 ENSG00000141013 Growth arrest specific 8 16 90019629-90044975 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041311, HPA048238 Approved Approved Plasma membrane
Cytosol Renal cancer:1.09e-7 (favourable), Endometrial cancer:3.01e-4 (favourable), Pancreatic cancer:7.67e-4 (favourable) Expressed in all Mixed fallopian tube: 30.0 Mixed +MED9 FLJ10193, MED25 ENSG00000141026 Mediator complex subunit 9 17 17476986-17493226 Predicted intracellular proteins Evidence at protein level HPA056415 Uncertain Approved Nucleoplasm
Midbody Renal cancer:2.83e-9 (favourable), Pancreatic cancer:4.18e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 22.5 Expressed in all +NCOR1 hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1 ENSG00000141027 Nuclear receptor corepressor 1 17 16029157-16218185 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043246, HPA050288, HPA051168, CAB072830 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:7.92e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 84.7 Expressed in all +COPS3 CSN3, SGN3 ENSG00000141030 COP9 signalosome subunit 3 17 17246820-17281293 Predicted intracellular proteins Evidence at protein level HPA021997, HPA050557 Approved Supported Nucleus
Cytosol Renal cancer:8.65e-5 (unfavourable), Prostate cancer:1.56e-4 (unfavourable) Expressed in all Expressed in all testis: 162.6 Expressed in all +GID4 C17orf39, VID24 ENSG00000141034 GID complex subunit 4 homolog 17 18039292-18068404 Predicted intracellular proteins Evidence at protein level HPA044348 Uncertain Approved Cytosol Expressed in all Expressed in all testis: 62.9 Expressed in all +ZNF287 ZKSCAN13, ZSCAN45 ENSG00000141040 Zinc finger protein 287 17 16551387-16569206 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029290 Uncertain Approved Golgi apparatus Renal cancer:5.28e-5 (favourable) Mixed Mixed parathyroid gland: 13.0 Mixed +MYOCD MYCD ENSG00000141052 Myocardin 17 12665890-12768949 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB046485 Approved Mixed Tissue enhanced seminal vesicle: 28.9 smooth muscle: 22.9 Cell line enhanced BJ: 5.5;BJ hTERT+: 5.2;HBF TERT88: 10.1;hTEC/SVTERT24-B: 11.7;REH: 7.6 +KSR1 KSR, RSU2 ENSG00000141068 Kinase suppressor of ras 1 17 27456714-27626438 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB009623, HPA011215 Uncertain Renal cancer:6.54e-4 (unfavourable) Expressed in all Expressed in all placenta: 75.6 Cell line enhanced HDLM-2: 562.3;HEL: 176.9 +UTP4 CIRH1A, CIRHIN, FLJ14728, KIAA1988, NAIC, TEX292 ENSG00000141076 UTP4, small subunit processome component 16 69131291-69231130 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041139, HPA043542 Approved Supported Nucleoli fibrillar center Liver cancer:8.18e-7 (unfavourable), Ovarian cancer:2.88e-5 (favourable), Head and neck cancer:9.05e-5 (unfavourable) Expressed in all Expressed in all testis: 51.0 Expressed in all +RANBP10 KIAA1464 ENSG00000141084 RAN binding protein 10 16 67723066-67806652 Predicted intracellular proteins Evidence at protein level Renal cancer:7.52e-4 (favourable) Expressed in all Expressed in all bone marrow: 26.7 Expressed in all +CTRL ENSG00000141086 Chymotrypsin like 16 67927640-67932414 Enzymes, Predicted secreted proteins Evidence at protein level HPA034504, HPA034505 Enhanced Uncertain Nucleoplasm Not detected Tissue enriched 209 pancreas: 1629.9 ovary: 7.8 Mixed +DPEP3 ENSG00000141096 Dipeptidase 3 16 67975663-67980829 Enzymes, Predicted secreted proteins Evidence at protein level HPA031870, HPA058607 Enhanced Group enriched Tissue enriched 25 testis: 56.9 spleen: 2.3 Not detected +GFOD2 FLJ23802, MGC11335 ENSG00000141098 Glucose-fructose oxidoreductase domain containing 2 16 67674531-67719421 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040939, HPA041112 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:5.95e-4 (favourable), Renal cancer:8.66e-4 (favourable) Expressed in all Expressed in all esophagus,parathyroid gland: 22.7 Expressed in all +NOB1 ART-4, MST158, NOB1P, PSMD8BP1 ENSG00000141101 NIN1/PSMD8 binding protein 1 homolog 16 69741867-69754940 Predicted intracellular proteins Evidence at protein level HPA041522, HPA049430, HPA067411 Approved Approved Focal adhesion sites
Cytosol Head and neck cancer:4.21e-5 (unfavourable), Liver cancer:8.16e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 69.4 Expressed in all +PRPSAP2 PAP41 ENSG00000141127 Phosphoribosyl pyrophosphate synthetase associated protein 2 17 18840085-18931287 Predicted intracellular proteins Evidence at protein level HPA021881 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:3.71e-4 (favourable) Expressed in all Expressed in all lymph node: 61.1 Expressed in all +UNC45B CMYA4, UNC45 ENSG00000141161 Unc-45 myosin chaperone B 17 35147817-35189345 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA017861 Uncertain Supported Cytosol Group enriched Group enriched 21 heart muscle: 65.8;skeletal muscle: 68.0 prostate: 3.1 Group enriched 9 BEWO: 1.6;HSkMC: 1.8 +PCTP STARD2 ENSG00000141179 Phosphatidylcholine transfer protein 17 55750979-55842830 Predicted intracellular proteins Evidence at protein level HPA022979 Approved Approved Nucleus
Nucleoli Head and neck cancer:3.43e-6 (unfavourable) Expressed in all Expressed in all liver: 49.3 Expressed in all +OR4D1 OR4D3, TPCR16 ENSG00000141194 Olfactory receptor family 4 subfamily D member 1 17 58155133-58156156 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected lymph node,testis: 0.1 Not detected +TOM1L1 SRCASM ENSG00000141198 Target of myb1 like 1 membrane trafficking protein 17 54899387-54968646 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA022916 Uncertain Renal cancer:3.81e-6 (favourable), Colorectal cancer:1.61e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 116.9 Mixed +KIF2B ENSG00000141200 Kinesin family member 2B 17 53822901-53825213 Predicted intracellular proteins Evidence at protein level HPA023081, HPA023103, HPA024795 Uncertain Uncertain Nucleoli
Microtubules
Cytokinetic bridge
Mitotic spindle Not detected Tissue enriched 1329 testis: 132.9 all non-specific tissues: 0.0 Not detected +C17orf80 FLJ20721, HLC-8, MIG3, SPEP1 ENSG00000141219 Chromosome 17 open reading frame 80 17 73232233-73248947 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012896 Uncertain Approved Nucleoplasm
Vesicles Liver cancer:9.02e-6 (unfavourable), Colorectal cancer:1.43e-4 (favourable) Expressed in all Expressed in all testis: 71.9 Expressed in all +TOB1 APRO5, TOB, TROB, TROB1 ENSG00000141232 Transducer of ERBB2, 1 17 50862223-50867978 Predicted intracellular proteins Evidence at protein level HPA047839 Approved Approved Nucleoplasm
Vesicles Pancreatic cancer:5.04e-5 (unfavourable), Prostate cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 278.7 Expressed in all +VPS53 FLJ10979, HCCS1 ENSG00000141252 VPS53, GARP complex subunit 17 508668-721717 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA022988, HPA024446 Enhanced Approved Golgi apparatus
Cytosol Endometrial cancer:1.08e-5 (favourable), Pancreatic cancer:1.56e-5 (favourable) Expressed in all Mixed cerebral cortex: 9.3 Expressed in all +SPATA22 NYD-SP20 ENSG00000141255 Spermatogenesis associated 22 17 3440019-3513852 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 80 testis: 415.6 placenta: 5.1 Group enriched 8 K-562: 6.9;TIME: 8.9 +SGSM2 KIAA0397, RUTBC1 ENSG00000141258 Small G protein signaling modulator 2 17 2337498-2381058 Predicted intracellular proteins Evidence at protein level HPA021641, HPA024553 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:9.00e-6 (favourable), Head and neck cancer:3.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 78.0 Expressed in all +NPEPPS MP100, PSA ENSG00000141279 Aminopeptidase puromycin sensitive 17 47522942-47623276 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021453, HPA045649 Uncertain Supported Cytosol Colorectal cancer:3.39e-5 (favourable), Liver cancer:3.67e-5 (unfavourable) Expressed in all Expressed in all esophagus: 106.9 Expressed in all +SKAP1 SCAP1, SKAP55 ENSG00000141293 Src kinase associated phosphoprotein 1 17 48133440-48430275 Predicted intracellular proteins Evidence at protein level HPA002969, CAB025882, CAB055513 Enhanced Approved Nucleus
Plasma membrane
Cytosol Urothelial cancer:3.14e-4 (favourable), Breast cancer:5.07e-4 (favourable) Mixed Mixed lymph node: 33.6 Cell line enhanced CAPAN-2: 26.1;HDLM-2: 14.7;HMC-1: 11.3;Karpas-707: 11.5;RPMI-8226: 13.6;RPTEC TERT1: 17.6;U-266/70: 11.0 +LRRC46 MGC16309 ENSG00000141294 Leucine rich repeat containing 46 17 47831627-47837713 Predicted intracellular proteins Evidence at protein level HPA021882, HPA074893 Enhanced Approved Cytosol Endometrial cancer:2.11e-4 (favourable) Tissue enhanced Group enriched 13 fallopian tube: 120.7;testis: 55.6 lung: 6.5 Mixed +SCRN2 ENSG00000141295 Secernin 2 17 47837692-47841333 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022934, HPA023434 Enhanced Supported Nucleoplasm
Golgi apparatus Liver cancer:3.86e-4 (favourable), Urothelial cancer:5.83e-4 (favourable) Expressed in all Expressed in all adipose tissue: 84.3 Expressed in all +SSH2 KIAA1725 ENSG00000141298 Slingshot protein phosphatase 2 17 29625938-29930276 Enzymes, Predicted intracellular proteins Evidence at protein level CAB017189, HPA057099 Uncertain Expressed in all Expressed in all bone marrow: 35.7 Expressed in all +RHBDL3 RHBDL4, VRHO ENSG00000141314 Rhomboid like 3 17 32266176-32324661 Enzymes, Predicted membrane proteins Evidence at transcript level HPA059607 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 20.7 adrenal gland: 5.5 Cell line enhanced A549: 4.0;AF22: 4.3;HDLM-2: 5.7;NTERA-2: 6.4;U-2 OS: 4.6 +SPACA3 ALLP17, CT54, LYC3, LYZL3, SLLP1 ENSG00000141316 Sperm acrosome associated 3 17 32970376-32997877 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA023633 Enhanced Tissue enhanced Tissue enriched 17 testis: 77.5 pancreas: 4.5 Cell line enriched 17 U-266/70: 72.1 +ARSG KIAA1001 ENSG00000141337 Arylsulfatase G 17 68259182-68422731 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023245, HPA023285 Enhanced Renal cancer:7.04e-4 (favourable) Expressed in all Tissue enhanced epididymis: 48.6 thyroid gland: 18.9 Mixed +ABCA8 KIAA0822 ENSG00000141338 ATP binding cassette subfamily A member 8 17 68867292-68955392 Predicted membrane proteins, Transporters Evidence at protein level HPA044914 Enhanced Approved Nucleoplasm
Cytosol Mixed Mixed ovary: 67.5 Group enriched 6 ASC diff: 23.3;ASC TERT1: 52.5;HHSteC: 10.6;HSkMC: 41.5 +G6PC3 UGRP ENSG00000141349 Glucose-6-phosphatase catalytic subunit 3 17 44070735-44076344 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067052 Supported Endoplasmic reticulum Endometrial cancer:1.11e-4 (favourable), Liver cancer:9.61e-4 (unfavourable) Expressed in all Expressed in all epididymis: 84.3 Expressed in all +CLTC CLTCL2, Hc ENSG00000141367 Clathrin heavy chain 17 59619689-59696956 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010389, CAB011571, CAB017155, HPA059143 Approved Enhanced Vesicles
Mitotic spindle
Cytosol Urothelial cancer:2.02e-4 (unfavourable), Liver cancer:5.54e-4 (unfavourable), Cervical cancer:7.35e-4 (unfavourable), Colorectal cancer:7.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 365.5 Expressed in all +C17orf64 ENSG00000141371 Chromosome 17 open reading frame 64 17 60392429-60431421 Predicted intracellular proteins Evidence at protein level HPA044415 Enhanced Approved Nucleoplasm
Vesicles Not detected Tissue enriched 233 testis: 185.6 spleen: 0.7 Cell line enhanced MCF7: 4.4 +BCAS3 FLJ20128 ENSG00000141376 BCAS3, microtubule associated cell migration factor 17 60677453-61392838 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052409, HPA057289 Approved Supported Nucleoli Pancreatic cancer:1.23e-5 (favourable), Renal cancer:1.73e-5 (favourable), Cervical cancer:2.04e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.8 Expressed in all +PTRH2 BIT1, CFAP37, CGI-147, PTH2 ENSG00000141378 Peptidyl-tRNA hydrolase 2 17 59674636-59707626 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA012897 Supported Supported Mitochondria Renal cancer:1.01e-8 (unfavourable), Liver cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all epididymis: 43.9 Expressed in all +SS18 SSXT, SYT ENSG00000141380 SS18, nBAF chromatin remodeling complex subunit 18 26016253-26091217 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055741, HPA059539 Supported Approved Nucleoplasm
Cytosol Renal cancer:4.86e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 75.7 Expressed in all +TAF4B TAF2C2, TAFII105 ENSG00000141384 TATA-box binding protein associated factor 4b 18 26225936-26391685 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028937 Uncertain Supported Nucleoplasm
Nucleoli fibrillar center Urothelial cancer:1.72e-4 (unfavourable), Renal cancer:3.08e-4 (unfavourable) Mixed Mixed testis: 4.2 Cell line enhanced Daudi: 24.6 +AFG3L2 SCA28, SPAX5 ENSG00000141385 AFG3 like matrix AAA peptidase subunit 2 18 12328944-12377314 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA004479, HPA004480 Enhanced Enhanced Mitochondria Renal cancer:6.05e-14 (favourable), Endometrial cancer:8.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 123.6 Expressed in all +PRELID3A C18orf43, FLJ31484, HFL-EDDG1, SLMO1 ENSG00000141391 PRELI domain containing 3A 18 12407896-12432238 Predicted intracellular proteins Evidence at protein level Endometrial cancer:5.89e-7 (unfavourable) Mixed Mixed seminal vesicle: 16.6 Mixed +IMPA2 ENSG00000141401 Inositol monophosphatase 2 18 11981025-12030883 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029561 Approved Approved Nucleoplasm
Mitochondria Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all skin: 129.8 Cell line enhanced BEWO: 240.8;SiHa: 163.4 +GNAL ENSG00000141404 G protein subunit alpha L 18 11688956-11885685 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015464, HPA051160 Supported Approved Nucleus
Cytosol Mixed Mixed cerebral cortex: 28.8 Cell line enhanced Daudi: 18.9;HeLa: 17.7 +SLC39A6 LIV-1 ENSG00000141424 Solute carrier family 39 member 6 18 36108532-36129385 Predicted membrane proteins, Transporters Evidence at protein level HPA042377 Approved Liver cancer:5.33e-4 (unfavourable) Expressed in all Expressed in all prostate: 209.2 Expressed in all +RPRD1A FLJ10656, HsT3101, P15RS ENSG00000141425 Regulation of nuclear pre-mRNA domain containing 1A 18 35984387-36067576 Predicted intracellular proteins Evidence at protein level HPA040602 Supported Supported Nucleus
Golgi apparatus Expressed in all Expressed in all epididymis: 140.2 Expressed in all +C18orf21 HsT3108, PNAS-124, PNAS-131 ENSG00000141428 Chromosome 18 open reading frame 21 18 35972083-35979286 Predicted intracellular proteins Evidence at protein level HPA065505, HPA067322 Uncertain Approved Nucleoli
Plasma membrane Liver cancer:1.38e-6 (unfavourable), Ovarian cancer:1.81e-6 (favourable) Expressed in all Expressed in all testis: 59.6 Expressed in all +GALNT1 GalNAc-T1 ENSG00000141429 Polypeptide N-acetylgalactosaminyltransferase 1 18 35581117-35711834 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012628 Uncertain Expressed in all Expressed in all urinary bladder: 85.6 Expressed in all +ASXL3 KIAA1713 ENSG00000141431 Additional sex combs like 3, transcriptional regulator 18 33578577-33751192 Disease related genes, Predicted intracellular proteins Evidence at transcript level HPA039539, HPA040034 Uncertain Not detected Tissue enhanced ovary: 2.9 testis: 2.7 Group enriched 11 AF22: 2.4;HEK 293: 1.2;RPMI-8226: 5.8;SCLC-21H: 3.3;SH-SY5Y: 1.5 +ADCYAP1 PACAP ENSG00000141433 Adenylate cyclase activating polypeptide 1 18 904943-912172 Predicted secreted proteins Evidence at protein level HPA065887 Approved Renal cancer:2.91e-6 (favourable) Tissue enhanced Tissue enhanced appendix: 19.3;cerebral cortex: 16.0;gallbladder: 15.7 testis: 5.6 Cell line enriched 17 SCLC-21H: 20.8 +MEP1B ENSG00000141434 Meprin A subunit beta 18 32185069-32220404 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA029119 Enhanced Group enriched Group enriched 37 duodenum: 251.4;small intestine: 402.2 colon: 8.7 Cell line enhanced SCLC-21H: 6.6 +SLC25A52 MCART2 ENSG00000141437 Solute carrier family 25 member 52 18 31759562-31760880 Predicted membrane proteins Evidence at transcript level HPA046388, HPA058261 Uncertain Approved Mitochondria Not detected Tissue enriched 64 testis: 15.4 adipose tissue,skin: 0.2 Not detected +GAREM1 C18orf11, FAM59A, FLJ21610, GAREM ENSG00000141441 GRB2 associated regulator of MAPK1 subtype 1 18 32124877-32470484 Predicted intracellular proteins Evidence at protein level HPA040709, HPA042046 Approved Approved Nucleoplasm
Cytosol Renal cancer:5.49e-6 (favourable), Pancreatic cancer:6.73e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 13.7 Cell line enhanced hTERT-HME1: 23.0;RT4: 21.0;SH-SY5Y: 22.6 +ESCO1 EFO1, ESO1, KIAA1911 ENSG00000141446 Establishment of sister chromatid cohesion N-acetyltransferase 1 18 21529281-21600884 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042497 Approved Expressed in all Expressed in all testis: 36.6 Expressed in all +OSBPL1A ORP-1, ORP1, OSBPL1B ENSG00000141447 Oxysterol binding protein like 1A 18 24162044-24397880 Predicted intracellular proteins Evidence at protein level HPA040959, HPA043401 Supported Approved Nucleoplasm
Cytosol Renal cancer:4.98e-13 (favourable), Stomach cancer:1.86e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 131.1 Mixed +GATA6 ENSG00000141448 GATA binding protein 6 18 22169443-22202528 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB011581, HPA066629 Uncertain Supported Nucleus Renal cancer:1.92e-9 (unfavourable) Tissue enhanced Mixed adrenal gland: 50.8 Cell line enhanced BEWO: 51.6;CACO-2: 55.5 +GREB1L C18orf6, FLJ13687, KIAA1772 ENSG00000141449 Growth regulation by estrogen in breast cancer 1 like 18 21242242-21525417 Predicted intracellular proteins Evidence at protein level HPA041647, HPA044218 Uncertain Approved Nucleoli
Mitochondria Mixed Tissue enhanced testis: 11.5 thyroid gland: 5.8 Cell line enhanced AF22: 50.3;BEWO: 99.4;CACO-2: 39.5 +C18orf8 HsT2591, MIC-1, MIC1 ENSG00000141452 Chromosome 18 open reading frame 8 18 23503470-23531807 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA043589 Uncertain Uncertain Nucleus Liver cancer:3.94e-4 (unfavourable) Expressed in all Expressed in all testis: 33.0 Expressed in all +PELP1 MNAR ENSG00000141456 Proline, glutamate and leucine rich protein 1 17 4669774-4704337 Predicted intracellular proteins Evidence at protein level HPA053966, HPA056028, HPA060760 Supported Enhanced Nucleus
Nucleoli Pancreatic cancer:4.07e-5 (favourable), Liver cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all testis: 35.2 Expressed in all +NPC1 ENSG00000141458 NPC intracellular cholesterol transporter 1 18 23506184-23586898 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA026618, CAB070132, HPA077445 Approved Supported Nucleus
Vesicles Liver cancer:2.26e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 110.1 Expressed in all +SLC14A1 HsT1341, JK, RACH1, RACH2 ENSG00000141469 Solute carrier family 14 member 1 (Kidd blood group) 18 45724127-45752520 Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA058353, HPA059570 Supported Supported Vesicles Group enriched Group enriched 5 prostate: 137.8;urinary bladder: 49.9 cerebral cortex: 18.1 Cell line enriched 14 RT4: 97.7 +ARRB2 ARR2, BARR2, DKFZp686L0365 ENSG00000141480 Arrestin beta 2 17 4710489-4721499 Predicted intracellular proteins Evidence at protein level HPA065681 Supported Vesicles Prostate cancer:2.61e-5 (unfavourable), Cervical cancer:2.93e-5 (favourable) Expressed in all Expressed in all bone marrow: 171.5 Expressed in all +SLC13A5 NACT ENSG00000141485 Solute carrier family 13 member 5 17 6684713-6713567 Predicted membrane proteins, Transporters Evidence at protein level HPA044343, HPA057088 Approved Uncertain Nucleoplasm Tissue enriched Tissue enriched 9 liver: 118.4 salivary gland: 12.8 Cell line enriched 65 Hep G2: 39.1 +ZMYND15 DKFZp434N127 ENSG00000141497 Zinc finger MYND-type containing 15 17 4740015-4746119 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023286 Uncertain Nuclear speckles
Cytosol Expressed in all Tissue enhanced parathyroid gland: 15.7;testis: 29.5 lung: 7.5 Cell line enhanced A-431: 1.9;CAPAN-2: 1.8 +WRAP53 FLJ10385, TCAB1, WDR79 ENSG00000141499 WD repeat containing antisense to TP53 17 7686071-7703502 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023026, HPA028130, HPA029928 Enhanced Enhanced Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:4.70e-4 (unfavourable), Pancreatic cancer:8.26e-4 (favourable) Expressed in all Mixed fallopian tube: 21.8 Mixed +MINK1 B55, MAP4K6, MINK, YSK2, ZC3 ENSG00000141503 Misshapen like kinase 1 17 4833388-4898061 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056296 Approved Pancreatic cancer:2.77e-4 (favourable), Liver cancer:3.00e-4 (unfavourable), Prostate cancer:9.27e-4 (unfavourable) Expressed in all Expressed in all skin: 72.5 Expressed in all +SAT2 SSAT2 ENSG00000141504 Spermidine/spermine N1-acetyltransferase family member 2 17 7626234-7627876 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022136, HPA057096 Enhanced Endometrial cancer:8.76e-6 (favourable), Pancreatic cancer:6.05e-5 (favourable), Lung cancer:6.71e-4 (favourable) Expressed in all Expressed in all adrenal gland: 91.0 Mixed +ASGR1 CLEC4H1 ENSG00000141505 Asialoglycoprotein receptor 1 17 7173431-7179564 Predicted intracellular proteins Evidence at protein level HPA011954, HPA012852 Enhanced Supported Vesicles
Cell Junctions Tissue enriched Tissue enriched 13 liver: 236.1 testis: 17.6 Cell line enriched 25 Hep G2: 331.3 +PIK3R5 p101, P101-PI3K ENSG00000141506 Phosphoinositide-3-kinase regulatory subunit 5 17 8878911-8965712 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044505, HPA052247, HPA052412 Uncertain Supported Microtubule organizing center
Cytosol Expressed in all Tissue enhanced bone marrow: 55.2 spleen: 27.9 Cell line enhanced HDLM-2: 36.3;U-937: 8.8 +TP53 LFS1, p53 ENSG00000141510 Tumor protein p53 17 7661779-7687550 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters Evidence at protein level CAB002973, CAB039238, CAB039239, HPA051244, CAB072876 Enhanced Enhanced Nucleoplasm Endometrial cancer:1.35e-4 (favourable), Prostate cancer:5.01e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 50.3 Expressed in all +CCDC40 CILD15, FAP172, FLJ20753, FLJ32021, KIAA1640 ENSG00000141519 Coiled-coil domain containing 40 17 80036632-80100613 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA022974 Enhanced Approved Microtubules Renal cancer:2.45e-4 (unfavourable), Endometrial cancer:2.95e-4 (favourable) Mixed Tissue enhanced fallopian tube: 23.7 testis: 12.8 Cell line enhanced SCLC-21H: 14.2 +ARHGDIA GDIA1, RHOGDI ENSG00000141522 Rho GDP dissociation inhibitor alpha 17 81867721-81871406 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010005, HPA021407 Approved Enhanced Cytosol Lung cancer:7.63e-4 (unfavourable) Expressed in all Expressed in all appendix: 206.6 Expressed in all +TMC6 EVER1, EVIN1, LAK-4P ENSG00000141524 Transmembrane channel like 6 17 78110458-78132407 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA051430 Uncertain Stomach cancer:1.82e-4 (favourable), Urothelial cancer:3.20e-4 (favourable) Expressed in all Expressed in all spleen: 82.8 Cell line enhanced K-562: 99.9;SK-BR-3: 90.6 +SLC16A3 MCT3, MCT4 ENSG00000141526 Solute carrier family 16 member 3 17 82228397-82261129 Predicted membrane proteins, Transporters Evidence at protein level CAB017490, HPA021451 Approved Supported Nuclear membrane
Plasma membrane Liver cancer:1.19e-7 (unfavourable), Renal cancer:3.71e-7 (unfavourable), Lung cancer:2.02e-5 (unfavourable), Cervical cancer:6.07e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 74.3 Mixed +CARD14 BIMP2, CARMA2, PSORS2 ENSG00000141527 Caspase recruitment domain family member 14 17 80169992-80209331 Disease related genes, Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced skin: 17.8 esophagus: 7.0 Cell line enhanced MCF7: 6.3;SK-BR-3: 8.0;T-47d: 22.6 +TTYH2 C17orf29 ENSG00000141540 Tweety family member 2 17 74213514-74262020 Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:9.74e-5 (unfavourable) Group enriched Tissue enriched 6 cerebral cortex: 129.2 testis: 21.8 Cell line enhanced SK-MEL-30: 62.2 +RAB40B RAR, SEC4L ENSG00000141542 RAB40B, member RAS oncogene family 17 82654973-82698728 Predicted intracellular proteins Evidence at transcript level Renal cancer:2.95e-6 (favourable), Lung cancer:9.77e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 56.8 epididymis: 18.0 Mixed +EIF4A3 DDX48, EIF4AIII, KIAA0111 ENSG00000141543 Eukaryotic translation initiation factor 4A3 17 80135214-80147183 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA021878 Enhanced Supported Nucleoplasm Liver cancer:1.68e-5 (unfavourable), Colorectal cancer:3.57e-5 (favourable), Lung cancer:1.87e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 112.1 Expressed in all +CSNK1D CKID, CKIdelta, HCKID ENSG00000141551 Casein kinase 1 delta 17 82239023-82273731 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB015410 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:2.38e-6 (unfavourable), Pancreatic cancer:9.62e-5 (favourable), Endometrial cancer:7.04e-4 (unfavourable), Renal cancer:8.34e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 66.9 Expressed in all +ANAPC11 APC11, Apc11p, HSPC214, MGC882 ENSG00000141552 Anaphase promoting complex subunit 11 17 81890790-81900991 Predicted intracellular proteins Evidence at protein level HPA021989, HPA027838 Approved Enhanced Nucleoplasm
Nucleoli Expressed in all Expressed in all testis: 109.9 Expressed in all +TBCD ENSG00000141556 Tubulin folding cofactor D 17 82752064-82945922 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045200 Approved Liver cancer:2.39e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 58.6 Expressed in all +FN3KRP FLJ12171, FN3KL ENSG00000141560 Fructosamine 3 kinase related protein 17 82716683-82730328 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056172, HPA065831 Approved Approved Nucleoplasm Glioma:5.57e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 48.8 Expressed in all +NARF DKFZp434G0420, FLJ10067, IOP2 ENSG00000141562 Nuclear prelamin A recognition factor 17 82458180-82490537 Predicted intracellular proteins Evidence at protein level HPA053006 Supported Nucleus
Nucleoli Renal cancer:1.48e-10 (unfavourable), Cervical cancer:1.15e-4 (favourable) Expressed in all Expressed in all testis: 47.3 Expressed in all +RPTOR KIAA1303, KOG1, Mip1, raptor ENSG00000141564 Regulatory associated protein of MTOR complex 1 17 80544819-80966371 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013514, HPA064306 Approved Enhanced Nucleoplasm
Lysosomes
Cytosol Expressed in all Mixed cerebral cortex: 11.2 Expressed in all +FOXK2 ILF, ILF1 ENSG00000141568 Forkhead box K2 17 82519713-82644662 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027523 Approved Supported Nucleoplasm
Vesicles Liver cancer:1.24e-6 (unfavourable) Expressed in all Expressed in all testis: 53.2 Expressed in all +TRIM65 ENSG00000141569 Tripartite motif containing 65 17 75880335-75897003 Predicted intracellular proteins Evidence at protein level HPA021575, HPA021578, HPA064820 Approved Supported Nucleoplasm
Vesicles
Cytosol Liver cancer:4.74e-6 (unfavourable), Renal cancer:1.82e-5 (unfavourable) Expressed in all Expressed in all skin: 20.4 Expressed in all +CBX8 HPC3, PC3, RC1 ENSG00000141570 Chromobox 8 17 79792132-79801683 Predicted intracellular proteins Evidence at protein level HPA031462 Enhanced Enhanced Nucleoplasm Renal cancer:5.39e-7 (unfavourable), Liver cancer:3.94e-6 (unfavourable), Pancreatic cancer:3.84e-5 (favourable) Expressed in all Mixed epididymis: 13.2 Mixed +SECTM1 K12 ENSG00000141574 Secreted and transmembrane 1 17 82321024-82334074 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA051214 Approved Expressed in all Tissue enhanced small intestine: 96.6 duodenum: 64.4 Cell line enhanced SiHa: 125.5;U-2197: 82.3 +RNF157 KIAA1917 ENSG00000141576 Ring finger protein 157 17 76142453-76240373 Predicted intracellular proteins Evidence at protein level HPA021854, HPA021991, HPA023922 Uncertain Approved Golgi apparatus
Vesicles Mixed Tissue enhanced cerebral cortex: 60.6;testis: 57.3 skeletal muscle: 24.9 Cell line enhanced HDLM-2: 92.0;U-266/70: 38.2 +CEP131 AZ1, AZI1, KIAA1118 ENSG00000141577 Centrosomal protein 131 17 81189593-81222999 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024019 Approved Supported Microtubules
Cytokinetic bridge
Microtubule organizing center Liver cancer:9.68e-5 (unfavourable) Expressed in all Mixed testis: 17.3 Expressed in all +ZNF750 FLJ13841, Zfp750 ENSG00000141579 Zinc finger protein 750 17 82829435-82840578 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021573, HPA023012 Enhanced Mixed Tissue enhanced esophagus: 60.5;skin: 54.4 salivary gland: 13.0 Cell line enhanced BEWO: 16.4;hTCEpi: 4.5;MCF7: 3.6;SK-BR-3: 9.5 +WDR45B WDR45L, WIPI3 ENSG00000141580 WD repeat domain 45B 17 82614562-82648553 Predicted intracellular proteins Evidence at protein level HPA017886 Approved Nucleus
Golgi apparatus
Cytosol Liver cancer:2.98e-5 (unfavourable) Expressed in all Expressed in all testis: 82.9 Expressed in all +CBX4 hPC2, NBP16, PC2 ENSG00000141582 Chromobox 4 17 79833156-79839429 Predicted intracellular proteins Evidence at protein level HPA008228, HPA012021 Approved Enhanced Nucleoplasm
Nuclear bodies Renal cancer:8.72e-8 (unfavourable) Expressed in all Tissue enhanced bone marrow: 85.1 cerebral cortex: 25.6 Expressed in all +RNF165 ARKL2, RNF111L2 ENSG00000141622 Ring finger protein 165 18 46326809-46463140 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041615, HPA047798 Uncertain Approved Nucleus
Plasma membrane Mixed Tissue enhanced cerebral cortex: 9.3;parathyroid gland: 9.8 thyroid gland: 7.0 Cell line enhanced AF22: 13.9;SCLC-21H: 17.1;SH-SY5Y: 17.5 +DYM DMC, FLJ20071, SMC ENSG00000141627 Dymeclin 18 49041474-49461347 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043551, HPA049187 Approved Supported Golgi apparatus Renal cancer:2.76e-5 (favourable), Urothelial cancer:5.26e-5 (unfavourable) Expressed in all Expressed in all testis: 80.2 Expressed in all +MAPK4 Erk3-related, Erk4, PRKM4 ENSG00000141639 Mitogen-activated protein kinase 4 18 50560078-50731824 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Group enriched Tissue enhanced adrenal gland: 29.7;cerebral cortex: 33.4;parathyroid gland: 60.1 seminal vesicle: 13.9 Cell line enhanced SCLC-21H: 13.6;SH-SY5Y: 3.0 +ELAC1 D29 ENSG00000141642 ElaC ribonuclease Z 1 18 50967991-50988121 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040867, HPA066483 Approved Supported Nucleus
Cytosol Renal cancer:8.43e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 17.8 Expressed in all +MBD1 CXXC3, PCM1 ENSG00000141644 Methyl-CpG binding domain protein 1 18 50266882-50281774 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009017, CAB036003, HPA068850 Approved Enhanced Nucleoplasm
Vesicles Prostate cancer:1.70e-6 (unfavourable), Liver cancer:5.08e-6 (unfavourable) Expressed in all Expressed in all testis: 109.0 Expressed in all +SMAD4 DPC4, MADH4 ENSG00000141646 SMAD family member 4 18 51028394-51085045 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019154 Approved Supported Nucleoplasm
Centrosome
Cytosol Renal cancer:1.92e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 39.3 Expressed in all +TNFRSF11A CD265, FEO, LOH18CR1, PDB2, RANK ENSG00000141655 TNF receptor superfamily member 11a 18 62325287-62391292 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB010391, HPA027728, HPA047976 Uncertain Supported Plasma membrane
Cytosol Mixed Tissue enhanced duodenum: 30.6 small intestine: 20.5 Cell line enhanced HDLM-2: 116.8;PC-3: 18.0;SCLC-21H: 24.0 +ZCCHC2 C18orf49, FLJ20222, FLJ20281, KIAA1744 ENSG00000141664 Zinc finger CCHC-type containing 2 18 62523007-62587709 Predicted intracellular proteins Evidence at protein level HPA040943 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all testis: 22.4 Mixed +FBXO15 FBX15, MGC39671 ENSG00000141665 F-box protein 15 18 74073353-74147865 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced fallopian tube: 4.9;testis: 6.6 cerebral cortex,epididymis: 2.0 Cell line enhanced SCLC-21H: 2.6 +CBLN2 ENSG00000141668 Cerebellin 2 precursor 18 72536680-72638521 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Group enriched 7 cerebral cortex: 30.2;seminal vesicle: 7.3 small intestine: 2.8 Cell line enriched 8 SH-SY5Y: 57.5 +PMAIP1 APR, NOXA ENSG00000141682 Phorbol-12-myristate-13-acetate-induced protein 1 18 59899948-59904306 Predicted intracellular proteins Evidence at protein level HPA051063 Uncertain Approved Vesicles Renal cancer:3.15e-6 (unfavourable) Expressed in all Tissue enhanced bone marrow: 55.8 placenta: 18.4 Cell line enhanced U-138 MG: 194.4 +P3H4 LEPREL4, NO55, SC65 ENSG00000141696 Prolyl 3-hydroxylase family member 4 (non-enzymatic) 17 41801947-41812604 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:4.48e-6 (unfavourable) Expressed in all Mixed thyroid gland: 18.3 Mixed +NT5C3B cN-IIIB, MGC20781, NT5C3L ENSG00000141698 5'-nucleotidase, cytosolic IIIB 17 41825181-41836263 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030786, HPA057095 Approved Liver cancer:8.11e-5 (unfavourable), Pancreatic cancer:2.67e-4 (favourable) Expressed in all Expressed in all thyroid gland: 79.2 Mixed +FAM134C DKFZp686B1036, FLJ33806 ENSG00000141699 Family with sequence similarity 134 member C 17 42579513-42610623 Predicted membrane proteins Evidence at protein level HPA016492 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Endometrial cancer:1.61e-4 (favourable), Renal cancer:6.82e-4 (unfavourable) Expressed in all Expressed in all testis: 48.2 Expressed in all +ERBB2 CD340, HER-2, HER2, NEU, NGL ENSG00000141736 Erb-b2 receptor tyrosine kinase 2 17 39687914-39730426 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555 Enhanced Supported Plasma membrane
Cytosol Renal cancer:2.41e-14 (favourable), Endometrial cancer:8.99e-8 (unfavourable), Pancreatic cancer:9.17e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 124.5 Cell line enriched 22 SK-BR-3: 2343.7 +GRB7 ENSG00000141738 Growth factor receptor bound protein 7 17 39737927-39747291 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB005226, HPA057084, CAB073538 Approved Supported Plasma membrane Endometrial cancer:6.60e-7 (unfavourable), Renal cancer:8.23e-5 (favourable), Ovarian cancer:3.10e-4 (unfavourable), Pancreatic cancer:6.90e-4 (unfavourable) Mixed Mixed fallopian tube: 35.1 Cell line enriched 8 SK-BR-3: 272.9 +MIEN1 C17orf37, C35, MGC14832, ORB3, Rdx12, XTP4 ENSG00000141741 Migration and invasion enhancer 1 17 39728496-39730787 Predicted intracellular proteins Evidence at protein level HPA061344 Approved Expressed in all Expressed in all prostate: 41.0 Cell line enriched 5 SK-BR-3: 451.5 +PNMT PENT ENSG00000141744 Phenylethanolamine N-methyltransferase 17 39667981-39670475 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017029, HPA043412, HPA051005 Enhanced Endometrial cancer:3.95e-5 (unfavourable) Tissue enhanced Tissue enriched 8 adrenal gland: 226.6 seminal vesicle: 29.2 Cell line enhanced HEL: 4.8;K-562: 10.4;NB-4: 14.5;SCLC-21H: 7.0;SH-SY5Y: 5.8 +ARL5C ARL12 ENSG00000141748 ADP ribosylation factor like GTPase 5C 17 39156894-39167484 Predicted intracellular proteins No evidence HPA069849 Uncertain Not detected Not detected lymph node: 0.4 Not detected +STAC2 24b2 ENSG00000141750 SH3 and cysteine rich domain 2 17 39210536-39225872 Predicted intracellular proteins Evidence at protein level HPA017288 Approved Nucleoplasm
Vesicles Endometrial cancer:4.05e-5 (unfavourable), Glioma:5.04e-4 (unfavourable), Ovarian cancer:6.66e-4 (unfavourable) Group enriched Group enriched 6 breast: 32.0;cerebral cortex: 30.1;epididymis: 13.8;seminal vesicle: 35.6 skin: 4.5 Cell line enhanced HeLa: 22.2;hTEC/SVTERT24-B: 4.8;U-87 MG: 14.4 +IGFBP4 BP-4, HT29-IGFBP, IBP4, IGFBP-4 ENSG00000141753 Insulin like growth factor binding protein 4 17 40443461-40457731 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA066240 Supported Renal cancer:2.72e-5 (unfavourable), Endometrial cancer:3.54e-4 (favourable), Liver cancer:5.49e-4 (favourable) Expressed in all Expressed in all smooth muscle: 932.6 Cell line enhanced A549: 1206.8;HSkMC: 1458.4 +FKBP10 FKBP6, FLJ20683, FLJ22041, FLJ23833, hFKBP65 ENSG00000141756 FK506 binding protein 10 17 41812680-41823217 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051171, HPA057021 Enhanced Approved Vesicles Renal cancer:0.00e+0 (unfavourable), Thyroid cancer:3.43e-5 (unfavourable), Cervical cancer:4.16e-4 (unfavourable), Urothelial cancer:4.99e-4 (unfavourable) Expressed in all Mixed placenta: 84.7 Mixed +TXNL4A DIB1, DIM1, HsT161, SNRNP15, TXNL4, U5-15kD ENSG00000141759 Thioredoxin like 4A 18 79970811-80033949 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041324 Approved Nucleus
Nuclear membrane
Cytosol Liver cancer:3.38e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 82.5 Expressed in all +CACNA1A APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6 ENSG00000141837 Calcium voltage-gated channel subunit alpha1 A 19 13206442-13633025 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA064258, HPA071902 Enhanced Uncertain Endoplasmic reticulum Pancreatic cancer:4.32e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 15.1 stomach: 3.5 Group enriched 7 SCLC-21H: 56.1;U-87 MG: 26.1 +MISP3 ENSG00000141854 MISP family member 3 19 14072536-14075062 Predicted intracellular proteins Evidence at protein level HPA042225 Uncertain Stomach cancer:3.11e-5 (favourable), Renal cancer:9.52e-4 (favourable) Expressed in all Mixed small intestine: 8.5 Cell line enhanced Karpas-707: 7.7;RPMI-8226: 8.7 +SAMD1 ENSG00000141858 Sterile alpha motif domain containing 1 19 14087840-14091036 Predicted intracellular proteins Evidence at protein level HPA041662, HPA049059 Uncertain Approved Mitochondria
Cytosol Liver cancer:1.96e-5 (unfavourable), Renal cancer:7.98e-5 (unfavourable), Cervical cancer:7.41e-4 (favourable), Stomach cancer:8.31e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 32.2 Expressed in all +BRD4 CAP, HUNK1, HUNKI, MCAP ENSG00000141867 Bromodomain containing 4 19 15235519-15332545 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA015055, HPA061646, CAB068177, CAB068178 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all placenta: 41.9 Expressed in all +SLC39A3 ZIP3 ENSG00000141873 Solute carrier family 39 member 3 19 2732204-2740152 Predicted membrane proteins, Transporters Evidence at protein level HPA042139, HPA058526 Uncertain Approved Vesicles Endometrial cancer:9.76e-5 (favourable) Expressed in all Expressed in all testis: 110.2 Cell line enhanced U-937: 326.0 +NFIC CTF, CTF5, NF-I, NFI ENSG00000141905 Nuclear factor I C 19 3359563-3469217 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004300, CAB004674, HPA052625 Supported Enhanced Nucleus
Nucleoli fibrillar center Endometrial cancer:1.52e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 68.9 Cell line enhanced SiHa: 191.4 +TPGS1 C19orf20, GTRGEO22, PGs1 ENSG00000141933 Tubulin polyglutamylase complex subunit 1 19 507497-519654 Predicted intracellular proteins Evidence at protein level Endometrial cancer:2.24e-4 (favourable), Pancreatic cancer:8.82e-4 (favourable) Expressed in all Mixed cerebral cortex: 6.6 Cell line enhanced HEK 293: 32.8;SH-SY5Y: 38.0 +PLPP2 LPP2, PAP-2c, PPAP2C ENSG00000141934 Phospholipid phosphatase 2 19 281040-291504 Enzymes, Predicted membrane proteins Evidence at protein level HPA055540 Uncertain Approved Mitochondria Endometrial cancer:3.21e-8 (favourable), Breast cancer:4.55e-4 (unfavourable) Expressed in all Tissue enhanced fallopian tube: 128.6 cervix, uterine: 92.0 Cell line enhanced A549: 122.2;CAPAN-2: 128.0 +ZIM3 ZNF657 ENSG00000141946 Zinc finger imprinted 3 19 57134096-57145202 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA034575 Uncertain Not detected Not detected testis: 0.7 Not detected +PRDM15 C21orf83, ZNF298 ENSG00000141956 PR/SET domain 15 21 41798225-41879482 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024268, HPA029255, HPA029256 Uncertain Supported Nucleoplasm
Nuclear bodies Expressed in all Mixed lymph node: 8.8 Cell line enhanced Daudi: 21.6;U-698: 37.6 +PFKL ENSG00000141959 Phosphofructokinase, liver type 21 44300051-44327376 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030047 Approved Approved Nucleoli
Mitochondria Ovarian cancer:4.41e-4 (unfavourable) Expressed in all Expressed in all small intestine: 101.7 Expressed in all +FEM1A ENSG00000141965 Fem-1 homolog A 19 4791681-4801273 Predicted intracellular proteins Evidence at protein level HPA016565, HPA063622 Supported Nucleus
Golgi apparatus
Cytosol Mixed Tissue enriched 7 skeletal muscle: 94.0 parathyroid gland: 13.6 Expressed in all +VAV1 VAV ENSG00000141968 Vav guanine nucleotide exchange factor 1 19 6772714-6857366 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001864 Enhanced Approved Cytosol Renal cancer:1.48e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 57.6 appendix: 53.0 Cell line enhanced HMC-1: 96.0;Karpas-707: 90.4;MOLT-4: 100.9;U-937: 80.7 +MVB12A FAM125A, FLJ32495 ENSG00000141971 Multivesicular body subunit 12A 19 17405722-17433724 Predicted intracellular proteins Evidence at protein level HPA041885, HPA042231 Approved Supported Nucleoplasm
Golgi apparatus Cervical cancer:3.26e-4 (favourable) Expressed in all Expressed in all ovary: 38.1 Expressed in all +CIB3 KIP3 ENSG00000141977 Calcium and integrin binding family member 3 19 16161368-16173525 Predicted intracellular proteins Evidence at protein level HPA043553 Uncertain Tissue enriched Not detected bone marrow: 0.8 Cell line enhanced HMC-1: 3.9;MCF7: 1.7;U-937: 1.6 +SH3GL1 CNSA1, EEN, MGC111371, SH3D2B, SH3P8 ENSG00000141985 SH3 domain containing GRB2 like 1, endophilin A2 19 4360370-4400547 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021485 Approved Enhanced Cytosol Renal cancer:9.36e-8 (unfavourable), Liver cancer:1.10e-4 (unfavourable), Cervical cancer:1.50e-4 (favourable), Endometrial cancer:1.86e-4 (favourable) Expressed in all Expressed in all esophagus: 114.5 Expressed in all +DUS3L DUS3, FLJ13896 ENSG00000141994 Dihydrouridine synthase 3 like 19 5784832-5791238 Predicted intracellular proteins Evidence at protein level HPA041854, HPA041944, HPA062846 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 26.7 Mixed +DPP9 ENSG00000142002 Dipeptidyl peptidase 9 19 4675224-4724673 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036059 Approved Supported Cytosol Renal cancer:3.38e-8 (unfavourable), Endometrial cancer:6.21e-5 (favourable), Stomach cancer:7.72e-5 (favourable), Breast cancer:4.96e-4 (favourable) Expressed in all Expressed in all appendix: 33.1 Expressed in all +DMRTC2 ENSG00000142025 DMRT like family C2 19 41844743-41852333 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045016 Uncertain Not detected Tissue enriched 128 testis: 48.6 lymph node,parathyroid gland,thyroid gland: 0.3 Not detected +CCDC97 FLJ40267, MGC20255 ENSG00000142039 Coiled-coil domain containing 97 19 41310189-41324883 Predicted intracellular proteins Evidence at protein level HPA043320, HPA043572 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.09e-4 (unfavourable) Expressed in all Expressed in all testis: 59.0 Expressed in all +TMEM91 FLJ27310, IFITMD6 ENSG00000142046 Transmembrane protein 91 19 41350911-41384083 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level HPA053240 Uncertain Renal cancer:3.52e-7 (unfavourable), Pancreatic cancer:3.54e-5 (favourable) Expressed in all Expressed in all skin: 31.1 Mixed +ZFP14 KIAA1559, ZNF531 ENSG00000142065 ZFP14 zinc finger protein 19 36334453-36379199 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA030637 Uncertain Approved Nuclear speckles Urothelial cancer:2.75e-5 (favourable) Expressed in all Mixed parathyroid gland: 8.4 Mixed +SIRT3 SIR2L3 ENSG00000142082 Sirtuin 3 11 215458-236931 Predicted intracellular proteins Evidence at protein level HPA026809, CAB037142 Approved Renal cancer:4.85e-9 (favourable), Endometrial cancer:8.51e-5 (favourable), Pancreatic cancer:4.45e-4 (favourable), Glioma:9.21e-4 (unfavourable) Expressed in all Expressed in all epididymis: 50.7 Expressed in all +IFITM3 1-8U ENSG00000142089 Interferon induced transmembrane protein 3 11 319669-327537 Predicted membrane proteins, Transporters Evidence at protein level HPA004337 Uncertain Renal cancer:5.78e-7 (unfavourable) Expressed in all Expressed in all smooth muscle: 1037.8 Cell line enhanced BJ hTERT+ SV40 Large T+: 1986.9;BJ hTERT+ SV40 Large T+ RasG12V: 2628.1;HHSteC: 2049.3 +PGGHG ATHL1, FLJ22635 ENSG00000142102 Protein-glucosylgalactosylhydroxylysine glucosidase 11 289135-296107 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039383, HPA058829 Uncertain Enhanced Cytosol Urothelial cancer:5.12e-4 (favourable) Expressed in all Expressed in all lymph node: 73.6 Mixed +HUNK ENSG00000142149 Hormonally up-regulated Neu-associated kinase 21 31873315-32044633 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027295, HPA027372 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:7.48e-5 (favourable) Mixed Mixed placenta: 6.8 Cell line enhanced AF22: 13.3;BEWO: 15.9;RH-30: 17.7;SCLC-21H: 17.5;SiHa: 14.1 +COL6A1 ENSG00000142156 Collagen type VI alpha 1 chain 21 45981737-46005050 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA019142, HPA029401 Enhanced Approved Cytosol Renal cancer:1.07e-8 (unfavourable), Urothelial cancer:4.54e-4 (unfavourable) Expressed in all Mixed placenta: 401.2 Cell line enhanced ASC TERT1: 1614.9;HHSteC: 849.5;HSkMC: 1234.5;U-138 MG: 1268.9 +IFNAR1 IFNAR, IFRC ENSG00000142166 Interferon alpha and beta receptor subunit 1 21 33324477-33359862 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018015, HPA029226 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 61.3 Expressed in all +SOD1 ALS, ALS1, IPOA ENSG00000142168 Superoxide dismutase 1 21 31659622-31668931 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001401, CAB008670 Enhanced Supported Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all liver: 768.9 Expressed in all +COL6A2 ENSG00000142173 Collagen type VI alpha 2 chain 21 46098097-46132849 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007029, HPA030920, HPA038799 Enhanced Approved Plasma membrane
Cytosol Renal cancer:8.72e-14 (unfavourable) Expressed in all Expressed in all placenta: 472.0 Cell line enhanced ASC TERT1: 1480.1;BJ: 903.2;HHSteC: 946.3;HSkMC: 1105.7;U-138 MG: 1108.3 +SIK1 msk, SNF1LK ENSG00000142178 Salt inducible kinase 1 21 43414515-43427128 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB023801, HPA038211 Approved Supported Cytosol Mixed Mixed seminal vesicle: 13.9 Cell line enhanced HaCaT: 18.5;HBEC3-KT: 22.7;HeLa: 32.3;hTCEpi: 25.9;SiHa: 16.7;U-266/84: 20.5 +DNMT3L MGC1090 ENSG00000142182 DNA methyltransferase 3 like 21 44246339-44262216 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055234, HPA066780 Uncertain Approved Nuclear speckles Tissue enriched Group enriched 6 kidney: 7.2;liver: 10.4;lymph node: 2.3 spleen: 1.1 Cell line enriched 7 BEWO: 40.9 +TRPM2 EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7 ENSG00000142185 Transient receptor potential cation channel subfamily M member 2 21 44350163-44443081 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA030976, HPA035260 Enhanced Approved Nuclear membrane Renal cancer:4.39e-6 (unfavourable), Urothelial cancer:7.59e-4 (favourable), Endometrial cancer:9.28e-4 (favourable) Expressed in all Mixed bone marrow: 18.8 Cell line enhanced HL-60: 33.1;NB-4: 37.1;THP-1: 48.2;U-937: 52.8 +SCYL1 GKLP, HT019, MGC78454, NKTL, NTKL, P105, TAPK, TEIF, TRAP ENSG00000142186 SCY1 like pseudokinase 1 11 65525077-65538704 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015015 Uncertain Supported Cytosol Expressed in all Expressed in all thyroid gland: 55.2 Expressed in all +TMEM50B C21orf4 ENSG00000142188 Transmembrane protein 50B 21 33432485-33480011 Predicted membrane proteins, Transporters Evidence at protein level CAB034199, HPA068995 Approved Approved Nucleoli fibrillar center Head and neck cancer:3.00e-4 (favourable), Lung cancer:3.33e-4 (favourable) Expressed in all Expressed in all thyroid gland: 74.6 Expressed in all +APP AD1 ENSG00000142192 Amyloid beta precursor protein 21 25880550-26171128 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB000157, HPA001462 Enhanced Approved Golgi apparatus
Vesicles Renal cancer:2.79e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 1203.4 Mixed +DOPEY2 C21orf5, KIAA0933 ENSG00000142197 Dopey family member 2 21 36156782-36294274 Predicted intracellular proteins Evidence at protein level CAB034922, HPA072065 Approved Approved Nucleoplasm
Mitochondria Breast cancer:7.08e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 85.6 Mixed +URB1 C21orf108, KIAA0539, NPA1 ENSG00000142207 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 21 32311018-32393026 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018334 Supported Supported Nucleoli fibrillar center Liver cancer:4.93e-4 (unfavourable) Expressed in all Expressed in all endometrium: 12.0 Expressed in all +AKT1 AKT, PKB, PRKBA, RAC ENSG00000142208 AKT serine/threonine kinase 1 14 104769349-104795751 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA002891, CAB003765 Enhanced Supported Nucleus
Microtubules Renal cancer:2.12e-4 (favourable), Ovarian cancer:4.83e-4 (favourable) Expressed in all Expressed in all prostate: 106.4 Expressed in all +IL19 IL-10C, IL-19, MDA1, NG.1, ZMDA1 ENSG00000142224 Interleukin 19 1 206798870-206842981 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 9 cervix, uterine: 21.0 salivary gland: 2.3 Cell line enriched 11 BJ hTERT+: 4.9 +EMP3 YMP ENSG00000142227 Epithelial membrane protein 3 19 48321509-48330553 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.31e-7 (unfavourable), Stomach cancer:3.13e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 200.5 Mixed +SAE1 AOS1, FLJ3091, Sua1 ENSG00000142230 SUMO1 activating enzyme subunit 1 19 47113274-47210636 Predicted intracellular proteins Evidence at protein level HPA041906, HPA043552 Enhanced Liver cancer:5.49e-8 (unfavourable), Renal cancer:8.15e-5 (unfavourable), Thyroid cancer:2.76e-4 (unfavourable) Expressed in all Expressed in all testis: 145.7 Expressed in all +NTN5 ENSG00000142233 Netrin 5 19 48661407-48673081 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Mixed Mixed endometrium,fallopian tube,ovary: 1.5 Not detected +LMTK3 KIAA1883, LMR3, PPP1R101, TYKLM3 ENSG00000142235 Lemur tyrosine kinase 3 19 48485271-48513189 Enzymes, Predicted membrane proteins Evidence at protein level HPA040203, HPA077070 Enhanced Approved Nucleoplasm
Cell Junctions Renal cancer:3.18e-8 (favourable) Mixed Group enriched 6 cerebral cortex: 20.3;parathyroid gland: 4.9 duodenum: 2.2 Cell line enhanced HMC-1: 6.1;SK-BR-3: 6.2;U-266/70: 5.9 +GEMIN7 FLJ13956 ENSG00000142252 Gem nuclear organelle associated protein 7 19 45079195-45091524 Predicted intracellular proteins Evidence at protein level HPA052075 Supported Nucleus
Cytosol Renal cancer:9.64e-11 (unfavourable), Liver cancer:5.86e-5 (unfavourable), Urothelial cancer:8.00e-4 (favourable) Expressed in all Expressed in all lymph node: 30.3 Expressed in all +CBLC CBL-3, CBL-SL, RNF57 ENSG00000142273 Cbl proto-oncogene C 19 44777869-44800634 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB008087, HPA035266 Approved Approved Nucleoplasm Renal cancer:3.11e-6 (favourable) Mixed Tissue enhanced duodenum: 52.5;skin: 41.9;small intestine: 44.0 colon: 21.4 Cell line enhanced A-431: 38.2;BEWO: 28.0;CACO-2: 23.9;CAPAN-2: 51.1;HaCaT: 37.6;HBEC3-KT: 25.9;RT4: 29.6;SK-BR-3: 24.0 +WTIP ENSG00000142279 Wilms tumor 1 interacting protein 19 34481638-34512304 Predicted intracellular proteins Evidence at protein level Mixed Mixed ovary: 34.3 Mixed +ADAMTS10 ADAM-TS10 ENSG00000142303 ADAM metallopeptidase with thrombospondin type 1 motif 10 19 8580242-8610735 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040223 Uncertain Uncertain Cytosol Renal cancer:4.55e-9 (unfavourable) Expressed in all Mixed endometrium: 5.9 Cell line enhanced NB-4: 24.4;REH: 9.3 +SLC6A3 DAT, DAT1 ENSG00000142319 Solute carrier family 6 member 3 5 1392790-1445430 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA012763, HPA013602, CAB016249, CAB078172 Supported Supported Approved Vesicles Renal cancer:3.40e-7 (unfavourable) Tissue enriched Not detected thyroid gland: 0.3 Not detected +RNPEPL1 ENSG00000142327 Arginyl aminopeptidase like 1 2 240565804-240581372 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036772 Uncertain Approved Nucleus
Nucleoli Liver cancer:5.06e-4 (unfavourable), Head and neck cancer:7.43e-4 (favourable) Expressed in all Expressed in all skin: 29.2 Mixed +CAPN10 ENSG00000142330 Calpain 10 2 240586716-240617705 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004170, HPA056098 Approved Approved Nucleoplasm
Cytosol Liver cancer:4.78e-6 (unfavourable), Pancreatic cancer:7.94e-5 (favourable), Head and neck cancer:8.47e-5 (favourable) Expressed in all Mixed skin,spleen: 14.5 Expressed in all +MYO1F ENSG00000142347 Myosin IF 19 8520790-8577577 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055242 Enhanced Renal cancer:3.27e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 50.4;bone marrow: 59.7;spleen: 63.3 lung: 23.4 Cell line enhanced HDLM-2: 45.8;HMC-1: 73.1;NB-4: 127.9;THP-1: 99.8;U-937: 61.8 +ERVK3-1 HERV-K(HML6-1) ENSG00000142396 Endogenous retrovirus group K3 member 1 19 58305319-58315663 Predicted intracellular proteins Evidence at transcript level Renal cancer:7.38e-4 (unfavourable), Liver cancer:9.45e-4 (unfavourable) Expressed in all Expressed in all epididymis: 46.6 Expressed in all +NLRP12 CLR19.3, Monarch1, NALP12, PAN6, PYPAF7, RNO2 ENSG00000142405 NLR family pyrin domain containing 12 19 53793603-53824394 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042981 Approved Tissue enriched Tissue enhanced appendix: 3.1;bone marrow: 4.1 spleen: 2.2 Cell line enhanced HMC-1: 3.9;THP-1: 2.7;U-87 MG: 4.2;U-937: 2.9 +CACNG8 ENSG00000142408 Calcium voltage-gated channel auxiliary subunit gamma 8 19 53963040-53990215 Predicted membrane proteins, Transporters Evidence at protein level HPA041351 Enhanced Tissue enriched Tissue enriched 34 cerebral cortex: 23.7 testis: 0.6 Cell line enhanced AF22: 7.2;HMC-1: 21.1;TIME: 12.3 +ZNF787 ENSG00000142409 Zinc finger protein 787 19 56087366-56121280 Predicted intracellular proteins Evidence at protein level HPA035140 Supported Approved Nucleus
Nucleoli
Mitochondria Expressed in all Expressed in all spleen: 19.3 Expressed in all +TIMM29 C19orf52 ENSG00000142444 Translocase of inner mitochondrial membrane 29 19 10928733-10933535 Predicted intracellular proteins Evidence at protein level HPA041858 Approved Approved Nucleoplasm
Mitochondria Stomach cancer:7.03e-7 (favourable), Cervical cancer:9.93e-5 (favourable) Expressed in all Expressed in all cerebral cortex,testis: 7.5 Expressed in all +FBN3 ENSG00000142449 Fibrillin 3 19 8065402-8149846 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049482 Uncertain Endometrial cancer:5.15e-4 (unfavourable) Tissue enhanced Tissue enhanced lung: 2.1;thyroid gland: 1.8 cerebral cortex,salivary gland: 1.1 Cell line enhanced CACO-2: 3.1;NTERA-2: 12.3;REH: 16.9 +CARM1 PRMT4 ENSG00000142453 Coactivator associated arginine methyltransferase 1 19 10871513-10923070 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB032961, HPA043561, HPA048073 Supported Enhanced Nucleoplasm Renal cancer:7.88e-6 (unfavourable), Urothelial cancer:8.37e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 37.1 Expressed in all +EVI5L ENSG00000142459 Ecotropic viral integration site 5 like 19 7830233-7864976 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043099, HPA043563 Approved Approved Nuclear bodies Renal cancer:2.18e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 41.6 Mixed +TM4SF5 ENSG00000142484 Transmembrane 4 L six family member 5 17 4771884-4783213 Predicted membrane proteins Evidence at protein level HPA055674 Uncertain Nucleoplasm
Plasma membrane
Cell Junctions Tissue enriched Group enriched 5 duodenum: 176.7;small intestine: 168.8 liver: 33.3 Group enriched 13 CACO-2: 45.1;Hep G2: 64.9 +SLC47A1 FLJ10847, MATE1 ENSG00000142494 Solute carrier family 47 member 1 17 19495385-19579034 Predicted membrane proteins, Transporters Evidence at protein level HPA021987 Enhanced Endometrial cancer:5.54e-8 (favourable), Renal cancer:1.06e-5 (favourable), Lung cancer:1.88e-5 (favourable) Tissue enhanced Tissue enhanced adrenal gland: 138.3;kidney: 105.1 liver: 53.8 Cell line enhanced A549: 19.2;AN3-CA: 15.5;Hep G2: 28.2;U-266/70: 23.7 +PSMB6 DELTA, Y ENSG00000142507 Proteasome subunit beta 6 17 4796144-4798503 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023312, HPA063656 Supported Supported Nucleoplasm
Cytosol Renal cancer:5.93e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 200.1 Expressed in all +GPR32 RVDR1 ENSG00000142511 G protein-coupled receptor 32 19 50770464-50771732 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 99 parathyroid gland: 260.1 placenta: 2.6 Cell line enriched 361 BEWO: 36.0 +SIGLEC10 MGC126774, PRO940, SIGLEC-10, SLG2 ENSG00000142512 Sialic acid binding Ig like lectin 10 19 51410021-51417803 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025807, HPA027093 Enhanced Supported Plasma membrane
Actin filaments
Cytosol Renal cancer:4.74e-5 (unfavourable) Expressed in all Tissue enhanced appendix: 48.4;spleen: 36.9 lymph node: 22.1 Cell line enhanced Daudi: 21.0;HEL: 13.5;HMC-1: 10.2;U-698: 14.8;U-937: 9.7 +ACPT ENSG00000142513 Acid phosphatase, testicular 19 50790415-50795224 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced skin: 1.4;testis: 2.2 parathyroid gland: 0.5 Cell line enhanced HEK 293: 1.3;U-266/84: 1.3 +KLK3 APS, PSA ENSG00000142515 Kallikrein related peptidase 3 19 50854915-50860764 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000070, HPA000764 Enhanced Tissue enriched Tissue enriched 365 prostate: 12913.0 seminal vesicle: 35.3 Group enriched 165 BEWO: 30.5;NB-4: 17.7;RPMI-8226: 12.8;SH-SY5Y: 11.1;U-2197: 10.1 +ZNF473 DKFZP434N043, HZFP100, KIAA1141 ENSG00000142528 Zinc finger protein 473 19 50025714-50053414 Predicted intracellular proteins Evidence at protein level HPA004191, HPA073309 Uncertain Supported Nucleoplasm Liver cancer:3.72e-4 (unfavourable) Expressed in all Tissue enriched 7 testis: 76.4 fallopian tube: 11.1 Expressed in all +FAM71E1 ENSG00000142530 Family with sequence similarity 71 member E1 19 50466785-50476753 Predicted intracellular proteins Evidence at transcript level HPA048111 Approved Nucleoli fibrillar center Renal cancer:5.35e-7 (favourable) Expressed in all Tissue enriched 11 testis: 38.4 cerebral cortex: 3.3 Cell line enhanced HEK 293: 13.1 +RPS11 S11 ENSG00000142534 Ribosomal protein S11 19 49496365-49499689 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA049719 Uncertain Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:3.50e-7 (unfavourable) Expressed in all Expressed in all ovary: 6662.2 Expressed in all +PTH2 TIP39 ENSG00000142538 Parathyroid hormone 2 19 49422414-49423441 Predicted secreted proteins Evidence at protein level Not detected Not detected testis: 0.2 Not detected +CTD-2545M3.6 ENSG00000142539 19 50415799-50428409 Predicted intracellular proteins Evidence at transcript level HPA018523 Uncertain Not detected Tissue enhanced appendix: 1.3;spleen: 1.8 duodenum,lymph node: 0.6 Cell line enhanced REH: 2.7;U-2 OS: 1.1;U-266/70: 1.2;U-698: 1.3 +RPL13A L13A, TSTA1 ENSG00000142541 Ribosomal protein L13a 19 49487554-49492308 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA038751 Approved Approved Nucleoli
Cytosol Renal cancer:1.44e-5 (unfavourable), Liver cancer:9.97e-4 (unfavourable) Expressed in all Expressed in all ovary: 4609.7 Expressed in all +CTU1 ATPBD3, MGC17332, NCS6 ENSG00000142544 Cytosolic thiouridylase subunit 1 19 51097606-51108370 Predicted intracellular proteins Evidence at protein level HPA053797 Uncertain Urothelial cancer:5.73e-5 (favourable) Expressed in all Mixed spleen: 2.8 Cell line enhanced HEK 293: 40.6 +NOSIP CGI-25 ENSG00000142546 Nitric oxide synthase interacting protein 19 49555711-49590262 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043464, HPA062132 Approved Enhanced Nucleus Expressed in all Expressed in all testis: 97.6 Expressed in all +IGLON5 LOC402665 ENSG00000142549 IgLON family member 5 19 51311848-51330354 Predicted secreted proteins Evidence at protein level HPA041994 Approved Uncertain Nucleus Renal cancer:5.62e-7 (unfavourable) Tissue enhanced Group enriched 7 adrenal gland: 2.3;cerebral cortex: 11.1;testis: 9.5 esophagus,seminal vesicle: 1.0 Group enriched 8 HMC-1: 30.8;NTERA-2: 16.0;SH-SY5Y: 24.3;U-2 OS: 6.9 +RCN3 RLP49 ENSG00000142552 Reticulocalbin 3 19 49527618-49546962 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA043134, HPA050402 Uncertain Approved Endoplasmic reticulum
Vesicles Renal cancer:5.80e-12 (unfavourable) Expressed in all Expressed in all small intestine: 45.0 Cell line enhanced ASC diff: 170.1;BJ: 238.6;fHDF/TERT166: 192.6 +ZNF614 FLJ21941 ENSG00000142556 Zinc finger protein 614 19 52012765-52030240 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021197 Uncertain Approved Nucleoplasm
Vesicles
Cytosol Expressed in all Mixed prostate: 14.0 Expressed in all +SLC2A5 GLUT5 ENSG00000142583 Solute carrier family 2 member 5 1 9035107-9088478 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005449 Enhanced Renal cancer:5.44e-5 (unfavourable) Group enriched Tissue enhanced duodenum: 109.0;small intestine: 92.6;testis: 139.9 bone marrow: 64.4 Cell line enhanced Daudi: 134.4;U-266/70: 111.0;U-698: 121.2;U-937: 52.9 +RERE ARG, ARP, ATN1L, DNB1, KIAA0458 ENSG00000142599 Arginine-glutamic acid dipeptide repeats 1 8352397-8817643 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024093 Uncertain Expressed in all Expressed in all endometrium: 93.2 Expressed in all +MMEL1 MMEL2, NEPII, NL1, NL2, SEP ENSG00000142606 Membrane metalloendopeptidase like 1 1 2590639-2632990 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007876, HPA008205, CAB020786 Uncertain Mixed Tissue enhanced testis: 5.4 stomach: 2.5 Cell line enhanced CAPAN-2: 2.1;EFO-21: 2.4;MCF7: 1.9;SK-BR-3: 10.6 +CFAP74 C1orf222, FLJ45476, KIAA1751 ENSG00000142609 Cilia and flagella associated protein 74 1 1921951-2003837 Predicted intracellular proteins Evidence at protein level HPA028521, HPA029274, HPA030240 Enhanced Tissue enhanced Tissue enhanced fallopian tube: 9.6;testis: 8.5 skin: 4.0 Mixed +PRDM16 KIAA1675, KMT8F, MEL1, MGC166915, PFM13 ENSG00000142611 PR/SET domain 16 1 3069168-3438621 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050343, HPA060467 Enhanced Nucleoplasm Thyroid cancer:4.70e-5 (unfavourable) Mixed Mixed thyroid gland: 7.6 Cell line enhanced AN3-CA: 1.4;CACO-2: 1.2;HAP1: 1.4;HEK 293: 1.6;HHSteC: 1.7;MCF7: 1.2 +CELA2A ELA2A ENSG00000142615 Chymotrypsin like elastase family member 2A 1 15456728-15472091 Enzymes, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 371 pancreas: 34335.1 ovary: 92.5 Cell line enhanced HMC-1: 1.1 +PADI3 PDI3 ENSG00000142619 Peptidyl arginine deiminase 3 1 17249098-17284233 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043739 Uncertain Approved Nucleoplasm
Vesicles Renal cancer:1.55e-11 (unfavourable), Endometrial cancer:3.22e-4 (unfavourable) Tissue enhanced Group enriched 10 esophagus: 3.7;seminal vesicle: 4.9;urinary bladder: 10.2 epididymis: 0.6 Cell line enhanced EFO-21: 13.2;RT4: 13.9;T-47d: 12.0 +FHAD1 KIAA1937 ENSG00000142621 Forkhead associated phosphopeptide binding domain 1 1 15247272-15400283 Predicted intracellular proteins Evidence at protein level HPA054284 Enhanced Mixed Group enriched 6 fallopian tube: 24.1;lung: 5.2;testis: 24.7 cervix, uterine: 3.1 Group enriched 5 HDLM-2: 27.2;HMC-1: 70.7;K-562: 16.4;U-87 MG: 42.0 +PADI1 HPAD10, PAD1, PDI, PDI1 ENSG00000142623 Peptidyl arginine deiminase 1 1 17205126-17246005 Enzymes, Predicted intracellular proteins Evidence at protein level HPA062294 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:8.34e-11 (unfavourable) Tissue enhanced Tissue enriched 7 esophagus: 37.1 skin: 5.4 Cell line enhanced CAPAN-2: 4.5;EFO-21: 2.3;HaCaT: 1.3;LHCN-M2: 1.6;RPTEC TERT1: 1.9 +EPHA2 ECK ENSG00000142627 EPH receptor A2 1 16124337-16156087 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level CAB010464 Supported Nuclear speckles
Golgi apparatus
Plasma membrane
Cell Junctions Expressed in all Tissue enhanced esophagus: 86.8 gallbladder: 44.5 Cell line enhanced PC-3: 211.2;WM-115: 253.0 +ARHGEF19 FLJ33962, WGEF ENSG00000142632 Rho guanine nucleotide exchange factor 19 1 16197854-16212609 Predicted intracellular proteins Evidence at protein level HPA068108 Approved Nuclear bodies Renal cancer:8.88e-5 (unfavourable), Lung cancer:6.53e-4 (favourable) Expressed in all Tissue enhanced skin: 20.9 thyroid gland: 11.5 Cell line enhanced T-47d: 23.8 +EFHD2 MGC4342 ENSG00000142634 EF-hand domain family member D2 1 15409895-15430343 Predicted intracellular proteins Evidence at protein level HPA048961 Enhanced Approved Cytosol Renal cancer:6.31e-9 (unfavourable), Urothelial cancer:3.60e-5 (favourable), Thyroid cancer:2.70e-4 (favourable), Lung cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 111.1 Expressed in all +PEX14 ENSG00000142655 Peroxisomal biogenesis factor 14 1 10472288-10630758 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046104, HPA049231 Supported Supported Nucleoli fibrillar center
Peroxisomes Expressed in all Expressed in all seminal vesicle: 32.7 Expressed in all +PGD ENSG00000142657 Phosphogluconate dehydrogenase 1 10398592-10420144 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031314, HPA031315 Enhanced Supported Approved Intermediate filaments
Cytosol Liver cancer:3.98e-4 (unfavourable) Expressed in all Expressed in all esophagus: 486.8 Expressed in all +MYOM3 FLJ35961 ENSG00000142661 Myomesin 3 1 24056035-24112175 Predicted intracellular proteins Evidence at protein level HPA028132, HPA029752 Uncertain Approved Vesicles Renal cancer:4.28e-6 (favourable) Tissue enhanced Group enriched 5 heart muscle: 69.9;kidney: 31.8;skeletal muscle: 86.5 testis: 12.1 Cell line enhanced A549: 4.2;Hep G2: 12.2 +SH3BGRL3 ENSG00000142669 SH3 domain binding glutamate rich protein like 3 1 26279176-26281522 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030848, HPA076219 Approved Approved Nuclear bodies Renal cancer:2.17e-10 (unfavourable) Expressed in all Expressed in all epididymis: 448.9 Expressed in all +CNKSR1 CNK, CNK1, KSR ENSG00000142675 Connector enhancer of kinase suppressor of Ras 1 1 26177403-26189886 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA030847 Uncertain Approved Cytosol Urothelial cancer:5.91e-4 (favourable) Mixed Mixed parathyroid gland: 20.6 Cell line enhanced A-431: 15.5;CAPAN-2: 23.4;HaCaT: 17.4 +RPL11 L11 ENSG00000142676 Ribosomal protein L11 1 23691779-23696425 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA002734, HPA074839 Approved Approved Vesicles Renal cancer:5.93e-6 (unfavourable), Breast cancer:2.55e-4 (favourable) Expressed in all Expressed in all ovary: 4915.9 Expressed in all +IL22RA1 CRF2-9, IL22R ENSG00000142677 Interleukin 22 receptor subunit alpha 1 1 24119771-24143121 Predicted membrane proteins Evidence at protein level Mixed Group enriched 5 colon: 11.3;duodenum: 20.2;esophagus: 10.1;pancreas: 26.1;rectum: 10.9;skin: 38.7;small intestine: 31.3 gallbladder: 4.0 Cell line enhanced CACO-2: 9.3;HaCaT: 4.5;Hep G2: 5.5 +ZNF593 ZT86 ENSG00000142684 Zinc finger protein 593 1 26169871-26170873 Predicted intracellular proteins Evidence at protein level HPA054363, HPA059387 Supported Enhanced Nucleus
Nucleoli Expressed in all Expressed in all breast: 16.4 Expressed in all +C1orf216 FLJ38984 ENSG00000142686 Chromosome 1 open reading frame 216 1 35713875-35719472 Predicted intracellular proteins Evidence at protein level HPA028299, HPA031343 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:7.68e-10 (unfavourable), Liver cancer:2.15e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 60.6 smooth muscle: 18.6 Expressed in all +KIAA0319L KIAA1837 ENSG00000142687 KIAA0319 like 1 35433490-35557950 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA072692 Approved Nucleoli
Golgi apparatus Liver cancer:5.92e-5 (unfavourable), Renal cancer:1.27e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 84.6 Expressed in all +EVA1B C1orf78, FAM176B, FLJ10647 ENSG00000142694 Eva-1 homolog B 1 36322031-36324154 Predicted intracellular proteins Evidence at protein level HPA041928, HPA043537 Approved Approved Cytosol Renal cancer:4.79e-5 (unfavourable), Breast cancer:4.58e-4 (favourable), Liver cancer:4.82e-4 (unfavourable) Expressed in all Mixed placenta: 14.6 Cell line enhanced BJ: 28.4 +C1orf94 MGC15882 ENSG00000142698 Chromosome 1 open reading frame 94 1 34166883-34219131 Predicted intracellular proteins Evidence at protein level HPA045805 Approved Nucleoplasm
Cytosol Tissue enriched Tissue enriched 32 testis: 42.4 cerebral cortex: 1.3 Group enriched 7 NTERA-2: 17.2;U-87 MG: 47.7 +DMRTA2 ENSG00000142700 DMRT like family A2 1 50417550-50423500 Predicted secreted proteins, Transcription factors Evidence at protein level HPA043098, HPA062958 Uncertain Approved Nucleoplasm
Mitochondria Tissue enhanced Not detected testis: 0.7 Cell line enhanced BEWO: 3.0;HBEC3-KT: 2.3;RH-30: 11.1;SH-SY5Y: 2.6;SiHa: 2.5 +PLK4 Sak, STK18 ENSG00000142731 Polo like kinase 4 4 127880861-127899195 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017327, HPA035026, HPA043198 Approved Supported Centrosome
Cytosol Colorectal cancer:7.46e-5 (favourable), Lung cancer:5.13e-4 (unfavourable), Pancreatic cancer:5.14e-4 (unfavourable) Expressed in all Tissue enhanced testis: 40.9 bone marrow: 13.9 Mixed +MAP3K6 ASK2, MAPKKK6, MEKK6 ENSG00000142733 Mitogen-activated protein kinase kinase kinase 6 1 27355184-27366892 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051192 Approved Approved Nucleus
Plasma membrane
Actin filaments
Cytosol Glioma:1.73e-4 (unfavourable), Head and neck cancer:7.26e-4 (favourable), Liver cancer:8.76e-4 (unfavourable) Expressed in all Tissue enhanced skin: 114.9 esophagus: 41.2 Mixed +FCN3 FCNH, HAKA1 ENSG00000142748 Ficolin 3 1 27369112-27374824 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB025945 Approved Mixed Group enriched 6 liver: 144.1;lung: 266.5 placenta: 33.0 Not detected +GPN2 ATPBD1B, FLJ10349 ENSG00000142751 GPN-loop GTPase 2 1 26876133-26890297 Predicted intracellular proteins Evidence at protein level HPA028059 Uncertain Liver cancer:3.56e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.3 Expressed in all +SYTL1 exophilin-7, FLJ14996, JFC1, SLP1 ENSG00000142765 Synaptotagmin like 1 1 27342020-27353937 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037825 Enhanced Endometrial cancer:6.83e-7 (favourable), Renal cancer:1.12e-5 (unfavourable) Mixed Mixed skin: 69.0 Cell line enhanced BEWO: 46.5;CAPAN-2: 49.3;NB-4: 51.8 +WDTC1 ADP, DCAF9, KIAA1037 ENSG00000142784 WD and tetratricopeptide repeats 1 1 27234516-27308633 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028177, HPA028180, HPA028182 Uncertain Supported Golgi apparatus
Vesicles Renal cancer:8.84e-8 (favourable), Cervical cancer:4.51e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 73.7 Expressed in all +CELA3A ELA3, ELA3A ENSG00000142789 Chymotrypsin like elastase family member 3A 1 22001656-22012539 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028086, HPA045650 Supported Approved Cytosol Tissue enriched Tissue enriched 352 pancreas: 56987.6 ovary: 161.9 Cell line enriched 24 MOLT-4: 20.6 +NBPF3 AE2 ENSG00000142794 Neuroblastoma breakpoint family member 3 1 21440128-21485005 Predicted intracellular proteins Evidence at protein level HPA042595, HPA043692, HPA044023, HPA046971, HPA058050 Supported Mixed Tissue enriched 6 testis: 20.4 breast,placenta: 3.4 Cell line enhanced BJ hTERT+: 12.6 +HSPG2 perlecan, PRCAN, SJS1 ENSG00000142798 Heparan sulfate proteoglycan 2 1 21822245-21937297 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB009820, HPA018892, CAB020718 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:2.82e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 135.6 Cell line enhanced EFO-21: 257.0;HUVEC TERT2: 511.1;TIME: 402.8 +ITGB3BP CENPR, HSU37139, NRIF3, TAP20 ENSG00000142856 Integrin subunit beta 3 binding protein 1 63440770-63593721 Predicted intracellular proteins Evidence at protein level HPA028463 Approved Supported Nucleoplasm Renal cancer:8.45e-6 (unfavourable), Liver cancer:7.24e-5 (unfavourable), Head and neck cancer:4.32e-4 (favourable) Expressed in all Mixed testis: 36.4 Expressed in all +SERBP1 CGI-55, CHD3IP, DKFZP564M2423, HABP4L, PAI-RBP1, PAIRBP1 ENSG00000142864 SERPINE1 mRNA binding protein 1 1 67407810-67430415 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020559, CAB026297 Enhanced Enhanced Cytosol Liver cancer:1.36e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 293.4 Expressed in all +BCL10 c-E10, CARMEN, CIPER, CLAP, mE10 ENSG00000142867 B-cell CLL/lymphoma 10 1 85266248-85277090 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB001944, HPA017925 Approved Approved Nucleoplasm Liver cancer:7.21e-7 (unfavourable), Colorectal cancer:2.51e-4 (favourable) Expressed in all Expressed in all gallbladder: 30.5 Expressed in all +CYR61 CCN1, GIG1, IGFBP10 ENSG00000142871 Cysteine rich angiogenic inducer 61 1 85580761-85583962 Predicted secreted proteins Evidence at protein level HPA029853 Uncertain Renal cancer:1.39e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 1095.9 Mixed +PRKACB PKACb ENSG00000142875 Protein kinase cAMP-activated catalytic subunit beta 1 84078062-84238498 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010363, HPA029754, HPA071185 Approved Approved Cytosol Renal cancer:1.89e-6 (favourable), Liver cancer:9.49e-4 (unfavourable) Expressed in all Tissue enriched 5 cerebral cortex: 316.3 adrenal gland: 63.1 Mixed +PIGK GPI8, hGPI8 ENSG00000142892 Phosphatidylinositol glycan anchor biosynthesis class K 1 77088990-77219430 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA056383, HPA057040 Uncertain Liver cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.4 Expressed in all +TINAGL1 ARG1, LCN7, LIECG3, P3ECSL, TINAGRP ENSG00000142910 Tubulointerstitial nephritis antigen like 1 1 31576485-31587686 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048695 Approved Renal cancer:3.65e-6 (favourable), Thyroid cancer:9.64e-4 (favourable) Expressed in all Tissue enhanced placenta: 268.9 adipose tissue: 102.6 Cell line enhanced BEWO: 313.9;EFO-21: 383.9;TIME: 309.9 +AZIN2 ADC, KIAA1945, ODC-p, ODC1L, ODCp ENSG00000142920 Antizyme inhibitor 2 1 33081104-33120530 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced testis: 30.1 cerebral cortex: 17.0 Cell line enhanced SK-MEL-30: 15.1 +RPS8 S8 ENSG00000142937 Ribosomal protein S8 1 44775251-44778779 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA029266 Supported Endoplasmic reticulum
Cytosol Renal cancer:9.05e-9 (unfavourable), Liver cancer:2.36e-5 (unfavourable) Expressed in all Expressed in all ovary: 5543.6 Expressed in all +KIF2C CT139, KNSL6, MCAK ENSG00000142945 Kinesin family member 2C 1 44739818-44767767 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006219 Supported Nucleoplasm
Midbody
Centrosome Renal cancer:0.00e+0 (unfavourable), Liver cancer:3.07e-7 (unfavourable), Pancreatic cancer:6.86e-4 (unfavourable) Expressed in all Tissue enriched 7 testis: 135.0 bone marrow: 20.4 Mixed +PTPRF LAR ENSG00000142949 Protein tyrosine phosphatase, receptor type F 1 43525187-43623666 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012710 Uncertain Approved Golgi apparatus Liver cancer:3.47e-4 (unfavourable), Stomach cancer:7.03e-4 (favourable) Expressed in all Mixed skin: 128.2 Mixed +BEST4 VMD2L2 ENSG00000142959 Bestrophin 4 1 44783585-44787705 Predicted membrane proteins Evidence at protein level HPA058564 Uncertain Mixed Tissue enhanced colon: 26.2;rectum: 21.3 duodenum: 11.3 Cell line enhanced Hep G2: 2.1 +MOB3C MOB1E, MOBKL2C ENSG00000142961 MOB kinase activator 3C 1 46607715-46616891 Predicted intracellular proteins Evidence at protein level HPA057744 Uncertain Intermediate filaments
Cytosol Cervical cancer:3.16e-5 (favourable) Expressed in all Expressed in all adipose tissue: 20.7 Mixed +CYP4B1 ENSG00000142973 Cytochrome P450 family 4 subfamily B member 1 1 46757838-46819413 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004331 Approved Supported Vesicles Cervical cancer:5.99e-4 (favourable) Tissue enhanced Tissue enhanced lung: 382.2 fallopian tube: 79.0 Cell line enriched 9 RT4: 234.9 +TMEM61 ENSG00000143001 Transmembrane protein 61 1 54980792-54992293 Predicted membrane proteins Evidence at transcript level HPA030614 Uncertain Renal cancer:1.78e-7 (favourable), Colorectal cancer:1.07e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 11.2;salivary gland: 10.1 seminal vesicle: 8.2 Cell line enriched 7 RPMI-8226: 16.2 +DMRTB1 ENSG00000143006 DMRT like family B with proline rich C-terminal 1 1 53459399-53467488 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036490, HPA058553 Enhanced Tissue enhanced Tissue enriched 67 testis: 69.6 epididymis: 1.0 Not detected +LMO4 ENSG00000143013 LIM domain only 4 1 87328468-87348923 Predicted intracellular proteins Evidence at protein level CAB022345, HPA045877, HPA061638 Approved Supported Nucleoplasm
Midbody ring Thyroid cancer:1.42e-4 (favourable), Ovarian cancer:1.47e-4 (favourable), Liver cancer:5.25e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 217.4 Expressed in all +SYPL2 Mg29 ENSG00000143028 Synaptophysin like 2 1 109466628-109482137 Predicted membrane proteins Evidence at protein level HPA018032 Approved Nucleoplasm Renal cancer:3.05e-4 (favourable) Mixed Tissue enriched 7 skeletal muscle: 129.4 parathyroid gland: 17.4 Cell line enhanced ASC diff: 22.2;BJ: 12.2;BJ hTERT+: 36.7;fHDF/TERT166: 18.3;HAP1: 12.5 +BARHL2 ENSG00000143032 BarH like homeobox 2 1 90711539-90717237 Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Tissue enriched 37 testis: 3.6 all non-specific tissues: 0.0 Cell line enhanced HAP1: 1.1;HEK 293: 3.4 +MTF2 M96, PCL2, TDRD19A ENSG00000143033 Metal response element binding transcription factor 2 1 93079235-93139081 Predicted intracellular proteins Evidence at protein level HPA069047, HPA069066 Enhanced Nucleoplasm Renal cancer:2.47e-7 (unfavourable), Liver cancer:8.90e-7 (unfavourable), Prostate cancer:1.05e-4 (unfavourable) Expressed in all Mixed testis: 30.7 Expressed in all +SLC44A3 CTL3, MGC45474 ENSG00000143036 Solute carrier family 44 member 3 1 94820342-94895246 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA047433 Enhanced Renal cancer:7.63e-5 (favourable) Expressed in all Mixed rectum: 38.5 Cell line enhanced RPTEC TERT1: 76.8;RT4: 55.4 +IGSF3 EWI-3, MGC117164, V8 ENSG00000143061 Immunoglobulin superfamily member 3 1 116574399-116667755 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036305, HPA036306 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.87e-6 (favourable), Liver cancer:4.03e-6 (unfavourable), Endometrial cancer:1.98e-4 (unfavourable), Pancreatic cancer:2.03e-4 (unfavourable) Expressed in all Mixed skin: 21.5 Cell line enhanced HDLM-2: 237.0;WM-115: 235.3 +ZNF697 MGC45731 ENSG00000143067 Zinc finger protein 697 1 119619422-119647773 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049933 Uncertain Approved Nucleoplasm Renal cancer:6.20e-5 (favourable) Expressed in all Mixed placenta: 10.9 Cell line enhanced SK-MEL-30: 35.9;WM-115: 45.9 +CTTNBP2NL DKFZp547A023 ENSG00000143079 CTTNBP2 N-terminal like 1 112396181-112463456 Predicted intracellular proteins Evidence at protein level HPA007301 Approved Approved Nucleoli fibrillar center
Cytosol Colorectal cancer:1.14e-4 (favourable), Renal cancer:8.08e-4 (favourable) Expressed in all Mixed placenta: 29.0 Mixed +STRIP1 FAM40A, FAR11A, FLJ14743, KIAA1761 ENSG00000143093 Striatin interacting protein 1 1 110031577-110074641 Predicted intracellular proteins Evidence at protein level HPA060302, HPA060498 Approved Supported Cytosol Expressed in all Expressed in all parathyroid gland: 34.8 Expressed in all +KCNA10 Kv1.8 ENSG00000143105 Potassium voltage-gated channel subfamily A member 10 1 110517217-110519175 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA015061, CAB022564 Uncertain Nucleoplasm
Cytosol Not detected Not detected testis: 0.8 Not detected +PSMA5 ZETA ENSG00000143106 Proteasome subunit alpha 5 1 109399031-109426427 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028392, HPA028398, HPA028441 Approved Approved Cytosol Colorectal cancer:1.45e-5 (favourable), Liver cancer:2.28e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 14.9 Cell line enhanced MOLT-4: 36.7 +FNDC7 FLJ35838 ENSG00000143107 Fibronectin type III domain containing 7 1 108712657-108742740 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028079, HPA054297 Enhanced Approved Nucleoplasm
Actin filaments Not detected Tissue enriched 12 testis: 2.0 bone marrow,cerebral cortex: 0.1 Not detected +C1orf162 MGC24133 ENSG00000143110 Chromosome 1 open reading frame 162 1 111473792-111478512 Predicted membrane proteins Evidence at protein level HPA026988 Approved Renal cancer:3.14e-6 (unfavourable) Expressed in all Expressed in all spleen: 129.3 Cell line enhanced HDLM-2: 121.3;HL-60: 50.8;THP-1: 33.7;U-937: 81.9 +CD53 MOX44, TSPAN25 ENSG00000143119 CD53 molecule 1 110873154-110899928 CD markers, Predicted membrane proteins, Transporters Evidence at protein level HPA047216 Approved Renal cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all lymph node: 462.7 Cell line enhanced Daudi: 353.2;HDLM-2: 199.1;HMC-1: 262.4;U-266/70: 196.6 +PROK1 EGVEGF, PK1, PRK1 ENSG00000143125 Prokineticin 1 1 110451200-110457354 Predicted secreted proteins Evidence at protein level Tissue enhanced Group enriched 9 ovary: 239.3;placenta: 75.8;testis: 119.4 seminal vesicle: 15.2 Cell line enriched 9 ASC diff: 16.3 +CELSR2 ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3 ENSG00000143126 Cadherin EGF LAG seven-pass G-type receptor 2 1 109250019-109275750 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013952 Uncertain Approved Cytosol Expressed in all Tissue enhanced cerebral cortex: 45.1 skin: 31.0 Cell line enhanced AF22: 49.6;HaCaT: 44.6;MCF7: 45.4 +ITGA10 ENSG00000143127 Integrin subunit alpha 10 1 145891208-145910189 Plasma proteins, Predicted membrane proteins Evidence at transcript level Breast cancer:7.18e-4 (favourable) Tissue enhanced Mixed cervix, uterine: 8.1 Cell line enhanced ASC TERT1: 35.3;HSkMC: 33.5;hTERT-HME1: 31.5;LHCN-M2: 60.2;TIME: 100.9 +GPR161 RE2 ENSG00000143147 G protein-coupled receptor 161 1 168079543-168137667 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level HPA015576, HPA072047 Uncertain Approved Nucleus
Nucleoli Mixed Tissue enhanced smooth muscle: 40.3 endometrium: 28.6 Mixed +ALDH9A1 ALDH4, ALDH7, ALDH9, E3 ENSG00000143149 Aldehyde dehydrogenase 9 family member A1 1 165662216-165698863 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA006077, HPA010873 Approved Approved Cytosol Pancreatic cancer:4.56e-4 (favourable) Expressed in all Expressed in all thyroid gland: 206.0 Mixed +ATP1B1 ATP1B ENSG00000143153 ATPase Na+/K+ transporting subunit beta 1 1 169105697-169132722 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA012911 Enhanced Renal cancer:7.08e-7 (favourable) Expressed in all Expressed in all kidney: 1337.2 Cell line enhanced RPTEC TERT1: 355.3;SH-SY5Y: 411.9 +TIPRL dJ69E11.3, MGC3794, TIP41, TIPRL1 ENSG00000143155 TOR signaling pathway regulator 1 168178933-168202114 Predicted intracellular proteins Evidence at protein level HPA027995, HPA054282 Approved Supported Vesicles
Cytosol Renal cancer:1.45e-8 (unfavourable), Liver cancer:1.60e-4 (unfavourable) Expressed in all Expressed in all endometrium: 38.5 Expressed in all +NME7 CFAP67, FLJ37194, NM23-H7 ENSG00000143156 NME/NM23 family member 7 1 169132531-169367967 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038014, HPA054289 Uncertain Approved Mitochondria Liver cancer:3.24e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 39.0 Expressed in all +POGK BASS2, KIAA15131, KRBOX2, LST003 ENSG00000143157 Pogo transposable element with KRAB domain 1 166839447-166856344 Predicted intracellular proteins Evidence at protein level HPA007838, HPA031630 Approved Supported Nucleoplasm
Vesicles Liver cancer:5.93e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.2 Expressed in all +MPC2 BRP44, DKFZP564B167 ENSG00000143158 Mitochondrial pyruvate carrier 2 1 167916729-167937040 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA056091 Uncertain Expressed in all Expressed in all testis: 355.9 Expressed in all +CREG1 CREG ENSG00000143162 Cellular repressor of E1A stimulated genes 1 1 167529677-167553767 Predicted secreted proteins Evidence at protein level HPA056390 Approved Vesicles
Microtubules Expressed in all Expressed in all thyroid gland: 209.5 Expressed in all +DCAF6 IQWD1, PC326 ENSG00000143164 DDB1 and CUL4 associated factor 6 1 167935783-168075843 Predicted intracellular proteins Evidence at protein level HPA054305 Supported Nucleus
Focal adhesion sites Expressed in all Expressed in all skeletal muscle: 223.5 Expressed in all +GPA33 A33 ENSG00000143167 Glycoprotein A33 1 167052836-167166479 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018858, CAB025943 Enhanced Tissue enriched Group enriched 8 colon: 183.6;duodenum: 130.8;rectum: 188.7;small intestine: 131.3 appendix: 19.0 Cell line enhanced NTERA-2: 1.0 +RXRG NR2B3 ENSG00000143171 Retinoid X receptor gamma 1 165400917-165445355 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002615, HPA012933 Uncertain Supported Nucleoplasm
Nuclear bodies Thyroid cancer:9.40e-5 (favourable) Group enriched Tissue enhanced skeletal muscle: 16.7 cervix, uterine: 4.7 Cell line enriched 6 SK-MEL-30: 29.1 +TBX19 dj747L4.1, TPIT ENSG00000143178 T-box 19 1 168281040-168314426 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005800, HPA072686 Supported Approved Nuclear speckles Renal cancer:4.55e-9 (unfavourable) Expressed in all Mixed endometrium: 5.4 Cell line enhanced HaCaT: 4.8 +UCK2 UMPK ENSG00000143179 Uridine-cytidine kinase 2 1 165827531-165911618 Enzymes, Predicted intracellular proteins Evidence at protein level HPA057128 Approved Nucleus Renal cancer:5.12e-13 (unfavourable), Liver cancer:9.22e-8 (unfavourable), Lung cancer:4.98e-4 (unfavourable), Melanoma:6.70e-4 (unfavourable) Expressed in all Expressed in all placenta: 41.1 Expressed in all +TMCO1 HP10122, TMCC4 ENSG00000143183 Transmembrane and coiled-coil domains 1 1 165724293-165827755 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA054768 Supported Endoplasmic reticulum Head and neck cancer:5.17e-7 (unfavourable), Renal cancer:1.25e-4 (unfavourable), Liver cancer:3.21e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 157.4 Expressed in all +XCL1 ATAC, LPTN, LTN, SCM-1, SCM-1a, SCYC1 ENSG00000143184 X-C motif chemokine ligand 1 1 168576473-168582077 Predicted secreted proteins Evidence at protein level HPA057725 Approved Mixed Tissue enhanced spleen: 5.7 endometrium: 3.3 Cell line enhanced CACO-2: 2.4;Hep G2: 2.5;SCLC-21H: 4.0;U-266/70: 3.7 +XCL2 SCM-1b, SCYC2 ENSG00000143185 X-C motif chemokine ligand 2 1 168540765-168543997 Predicted secreted proteins Evidence at protein level HPA057725 Approved Renal cancer:8.36e-9 (unfavourable), Lung cancer:3.17e-4 (favourable) Mixed Tissue enhanced spleen: 14.1 bone marrow: 8.4 Cell line enhanced CACO-2: 2.1 +POU2F1 OCT1, OTF1 ENSG00000143190 POU class 2 homeobox 1 1 167220829-167427345 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002608, HPA058559, HPA064323 Supported Supported Nucleoplasm
Endoplasmic reticulum
Vesicles Renal cancer:2.98e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 8.0 Mixed +MAEL CT128, FLJ14904, SPATA35 ENSG00000143194 Maelstrom spermatogenic transposon silencer 1 166975582-167022214 Predicted intracellular proteins Evidence at protein level HPA078602 Approved Tissue enhanced Tissue enriched 30 testis: 282.8 placenta: 9.3 Cell line enriched 11 NTERA-2: 3.3 +ILDR2 C1orf32 ENSG00000143195 Immunoglobulin like domain containing receptor 2 1 166895711-166975482 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012545 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 11.3;testis: 17.4 kidney: 3.1 Cell line enhanced AF22: 7.8;U-2 OS: 10.6;U-251 MG: 4.6 +DPT ENSG00000143196 Dermatopontin 1 168695459-168729264 Predicted secreted proteins Evidence at protein level HPA065548 Approved Vesicles Renal cancer:4.74e-5 (unfavourable) Expressed in all Mixed adipose tissue: 330.3 Group enriched 10 ASC diff: 94.1;fHDF/TERT166: 44.4 +MGST3 GST-III ENSG00000143198 Microsomal glutathione S-transferase 3 1 165630861-165661796 Enzymes, Predicted membrane proteins Evidence at protein level HPA053311 Approved Nucleus Expressed in all Expressed in all epididymis: 629.7 Expressed in all +ADCY10 HCA2, RP1-313L4.2, SAC, SACI, Sacy ENSG00000143199 Adenylate cyclase 10, soluble 1 167809388-167914215 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015243, HPA017749 Approved Tissue enhanced Tissue enriched 11 testis: 33.1 liver: 3.1 Cell line enhanced T-47d: 1.3 +RFWD2 COP1, FLJ10416, RNF200 ENSG00000143207 Ring finger and WD repeat domain 2 1 175944831-176207493 Enzymes, Predicted intracellular proteins Evidence at protein level Endometrial cancer:3.96e-4 (unfavourable) Expressed in all Expressed in all testis: 42.2 Expressed in all +NECTIN4 LNIR, nectin-4, PRR4, PVRL4 ENSG00000143217 Nectin cell adhesion molecule 4 1 161070995-161089599 Disease related genes, Predicted membrane proteins Evidence at protein level HPA010775 Enhanced Supported Plasma membrane Mixed Tissue enhanced esophagus: 45.9;skin: 79.5 breast,placenta: 17.1 Cell line enhanced BEWO: 53.8;HaCaT: 32.5;SK-BR-3: 35.3;T-47d: 28.8 +UFC1 HSPC155 ENSG00000143222 Ubiquitin-fold modifier conjugating enzyme 1 1 161152776-161158856 Predicted intracellular proteins Evidence at protein level HPA027481, HPA028722 Enhanced Approved Nuclear speckles
Cytosol Renal cancer:2.62e-6 (unfavourable) Expressed in all Expressed in all fallopian tube: 253.4 Expressed in all +PPOX PPO, VP ENSG00000143224 Protoporphyrinogen oxidase 1 161166410-161178013 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030123 Uncertain Approved Mitochondria
Cytosol Renal cancer:9.89e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 38.9 Expressed in all +FCGR2A CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2 ENSG00000143226 Fc fragment of IgG receptor IIa 1 161505430-161524013 CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010718, HPA014730 Enhanced Renal cancer:6.49e-7 (unfavourable) Expressed in all Tissue enhanced placenta: 160.6 appendix: 148.6 Cell line enhanced HEL: 26.6;HMC-1: 50.4;K-562: 16.0;THP-1: 42.6;U-937: 21.3 +NUF2 CDCA1, CT106, NUF2R ENSG00000143228 NUF2, NDC80 kinetochore complex component 1 163266576-163355764 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059692 Supported Nucleus Liver cancer:1.04e-5 (unfavourable), Melanoma:4.83e-4 (unfavourable), Lung cancer:9.16e-4 (unfavourable), Pancreatic cancer:9.75e-4 (unfavourable) Mixed Tissue enhanced testis: 95.1 lymph node: 21.8 Mixed +RGS5 ENSG00000143248 Regulator of G-protein signaling 5 1 163111121-163321791 Predicted intracellular proteins Evidence at protein level HPA001821 Approved Supported Cytosol Renal cancer:9.17e-4 (unfavourable) Expressed in all Mixed adrenal gland: 406.2 Group enriched 45 HUVEC TERT2: 1084.9;SH-SY5Y: 4496.0 +SDHC CYB560, cybL, PGL3 ENSG00000143252 Succinate dehydrogenase complex subunit C 1 161314257-161375340 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.20e-4 (favourable) Expressed in all Expressed in all kidney: 188.8 Expressed in all +PFDN2 ENSG00000143256 Prefoldin subunit 2 1 161100556-161118111 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028700, HPA058304 Approved Enhanced Cytosol Renal cancer:4.39e-8 (unfavourable), Head and neck cancer:9.10e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 109.6 Expressed in all +NR1I3 CAR, CAR1, MB67 ENSG00000143257 Nuclear receptor subfamily 1 group I member 3 1 161229666-161238302 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051365 Approved Nucleoplasm Tissue enriched Tissue enriched 9 liver: 82.5 kidney: 9.4 Cell line enhanced CACO-2: 3.7 +USP21 USP16, USP23 ENSG00000143258 Ubiquitin specific peptidase 21 1 161159450-161165723 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028397 Uncertain Supported Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:9.50e-6 (unfavourable), Urothelial cancer:3.35e-5 (favourable), Liver cancer:1.68e-4 (unfavourable), Endometrial cancer:7.05e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 45.7 Expressed in all +F13B FXIIIB ENSG00000143278 Coagulation factor XIII B chain 1 197039191-197067267 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA003827, HPA052139 Supported Liver cancer:6.78e-5 (favourable) Tissue enriched Tissue enriched 111 liver: 122.1 duodenum: 1.1 Not detected +PRCC RCCP1 ENSG00000143294 Papillary renal cell carcinoma (translocation-associated) 1 156750610-156800817 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017151, HPA019463, HPA019481 Supported Enhanced Nuclear speckles Renal cancer:8.99e-15 (unfavourable), Thyroid cancer:3.72e-4 (unfavourable), Endometrial cancer:5.55e-4 (unfavourable), Liver cancer:8.63e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 54.5 Expressed in all +FCRL5 BXMAS1, CD307e, FCRH5, IRTA2 ENSG00000143297 Fc receptor like 5 1 157513377-157552520 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced lymph node: 28.7;spleen: 20.5;tonsil: 32.8 appendix: 17.9 Cell line enhanced U-266/70: 2.5;U-698: 5.1 +RRNAD1 C1orf66, CGI-41, METTL25B ENSG00000143303 Ribosomal RNA adenine dimethylase domain containing 1 1 156728442-156736960 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA047426 Approved Approved Nucleoli
Cytosol Colorectal cancer:5.60e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 49.2 Expressed in all +MRPL24 MRP-L18 ENSG00000143314 Mitochondrial ribosomal protein L24 1 156737303-156741590 Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA030295, HPA054323 Approved Renal cancer:3.99e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 117.5 Expressed in all +PIGM GPI-MT-I ENSG00000143315 Phosphatidylinositol glycan anchor biosynthesis class M 1 160027673-160031991 Disease related genes, Predicted membrane proteins Evidence at protein level HPA047418 Uncertain Ovarian cancer:3.27e-4 (favourable) Expressed in all Mixed parathyroid gland: 16.3 Mixed +CASQ1 CASQ, PDIB1 ENSG00000143318 Calsequestrin 1 1 160190556-160201886 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA007845, CAB015170, HPA026823 Enhanced Uncertain Nucleoplasm
Mitochondria Urothelial cancer:8.93e-5 (favourable) Mixed Tissue enriched 33 skeletal muscle: 1514.0 esophagus: 45.3 Group enriched 9 BEWO: 18.6;HDLM-2: 35.6;RT4: 53.5 +ISG20L2 FLJ12671 ENSG00000143319 Interferon stimulated exonuclease gene 20 like 2 1 156721891-156728799 Predicted intracellular proteins Evidence at protein level HPA028005, HPA054285 Approved Supported Nucleoplasm Renal cancer:4.80e-5 (unfavourable), Liver cancer:6.15e-5 (unfavourable), Endometrial cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all testis: 86.1 Expressed in all +CRABP2 CRABP-II ENSG00000143320 Cellular retinoic acid binding protein 2 1 156699606-156705816 Predicted intracellular proteins Evidence at protein level HPA004135 Supported Supported Nucleoplasm
Cytosol Renal cancer:3.19e-13 (unfavourable), Endometrial cancer:2.11e-5 (unfavourable) Expressed in all Tissue enriched 5 esophagus: 1042.5 skin: 193.5 Cell line enhanced BJ hTERT+: 1263.6;MCF7: 468.2;T-47d: 1127.9 +HDGF HMG1L2 ENSG00000143321 Hepatoma derived growth factor 1 156742107-156766925 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB026035, HPA048728, HPA053422 Enhanced Enhanced Nucleoplasm Liver cancer:2.43e-8 (unfavourable), Endometrial cancer:6.02e-4 (unfavourable), Ovarian cancer:9.84e-4 (favourable) Expressed in all Expressed in all bone marrow: 190.4 Expressed in all +ABL2 ABLL, ARG ENSG00000143322 ABL proto-oncogene 2, non-receptor tyrosine kinase 1 179099327-179229684 Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA001866, CAB017106, HPA072754 Uncertain Supported Nucleoplasm Renal cancer:1.78e-7 (unfavourable), Cervical cancer:3.50e-4 (unfavourable), Urothelial cancer:8.40e-4 (unfavourable) Expressed in all Mixed gallbladder: 20.3 Expressed in all +XPR1 SYG1, X3 ENSG00000143324 Xenotropic and polytropic retrovirus receptor 1 1 180632004-180890251 Disease related genes, Predicted membrane proteins Evidence at protein level HPA016557 Enhanced Liver cancer:3.04e-4 (unfavourable) Expressed in all Expressed in all testis: 31.3 Expressed in all +RGS16 A28-RGS14, RGS-r ENSG00000143333 Regulator of G-protein signaling 16 1 182598623-182604408 Predicted intracellular proteins Evidence at protein level HPA053250, HPA055824 Uncertain Approved Cytosol Renal cancer:1.70e-4 (unfavourable) Expressed in all Tissue enriched 7 thyroid gland: 171.8 gallbladder: 25.1 Cell line enhanced Daudi: 77.3;SCLC-21H: 127.9;U-266/70: 93.7;U-698: 109.4 +TOR1AIP1 FLJ13142, LAP1B ENSG00000143337 Torsin 1A interacting protein 1 1 179882042-179925000 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047151, HPA050546 Enhanced Enhanced Nuclear membrane Expressed in all Expressed in all thyroid gland: 79.3 Expressed in all +FAM163A C1orf76, MGC16664, NDSP ENSG00000143340 Family with sequence similarity 163 member A 1 179743163-179816198 Predicted membrane proteins Evidence at transcript level HPA010778 Uncertain Mixed Tissue enhanced adrenal gland: 7.6;testis: 8.7 gallbladder: 1.8 Cell line enriched 38 SH-SY5Y: 118.8 +HMCN1 ARMD1, FBLN6, FIBL-6, FIBL6 ENSG00000143341 Hemicentin 1 1 185734551-186190949 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051677 Uncertain Renal cancer:3.59e-7 (unfavourable) Tissue enriched Tissue enhanced lung: 22.3 prostate: 12.6 Group enriched 6 fHDF/TERT166: 17.3;MCF7: 58.7;SK-MEL-30: 38.8;U-138 MG: 13.5;WM-115: 43.4 +RGL1 RGL ENSG00000143344 Ral guanine nucleotide dissociation stimulator like 1 1 183636085-183928531 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA019788 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Liver cancer:1.49e-5 (unfavourable), Lung cancer:4.32e-4 (favourable) Expressed in all Mixed spleen: 62.6 Cell line enhanced HSkMC: 39.9 +LYPLAL1 Q96AV0 ENSG00000143353 Lysophospholipase like 1 1 219173844-219212865 Predicted intracellular proteins Evidence at protein level HPA045806 Approved Supported Cytosol Renal cancer:1.31e-4 (favourable) Expressed in all Mixed kidney: 43.0 Mixed +LHX9 ENSG00000143355 LIM homeobox 9 1 197911902-197935478 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009695 Uncertain Approved Nucleus Mixed Tissue enhanced ovary: 11.5;testis: 4.5 lung: 2.2 Cell line enriched 9 fHDF/TERT166: 213.5 +PRUNE1 DRES-17, H-PRUNE, HTCD37, PRUNE ENSG00000143363 Prune exopolyphosphatase 1 151008420-151035713 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028411 Uncertain Supported Cytosol Renal cancer:3.48e-4 (unfavourable), Endometrial cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 53.9 Expressed in all +RORC NR1F3, RORG, RZRG, TOR ENSG00000143365 RAR related orphan receptor C 1 151806071-151831872 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA065620 Supported Nuclear bodies Renal cancer:2.94e-5 (favourable), Colorectal cancer:1.83e-4 (favourable) Mixed Mixed thyroid gland: 50.4 Cell line enhanced HDLM-2: 24.3;Karpas-707: 9.4;MOLT-4: 5.6;T-47d: 10.0 +TUFT1 ENSG00000143367 Tuftelin 1 1 151540305-151583583 Predicted intracellular proteins Evidence at protein level HPA028112, HPA054301 Approved Approved Approved Vesicles Endometrial cancer:4.83e-4 (unfavourable) Expressed in all Tissue enhanced skin: 92.8 esophagus: 25.8 Mixed +SF3B4 Hsh49, SAP49, SF3b49 ENSG00000143368 Splicing factor 3b subunit 4 1 149923317-149928344 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028578, HPA064660 Approved Approved Nuclear speckles Renal cancer:1.74e-7 (unfavourable), Liver cancer:1.54e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 72.6 Expressed in all +ECM1 ENSG00000143369 Extracellular matrix protein 1 1 150508062-150513789 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA027241 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:1.51e-9 (unfavourable), Urothelial cancer:1.20e-5 (unfavourable), Pancreatic cancer:3.55e-4 (unfavourable) Expressed in all Group enriched 6 epididymis: 581.9;esophagus: 989.7 tonsil: 122.7 Cell line enhanced ASC TERT1: 277.2;BJ hTERT+: 233.5;fHDF/TERT166: 213.1;hTEC/SVTERT24-B: 192.3 +ZNF687 KIAA1441 ENSG00000143373 Zinc finger protein 687 1 151281618-151292180 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021193, HPA023948 Approved Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 26.0 Expressed in all +TARS2 FLJ12528, TARSL1 ENSG00000143374 Threonyl-tRNA synthetase 2, mitochondrial (putative) 1 150487364-150507609 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028626 Approved Approved Nucleoplasm
Intermediate filaments
Cytosol Expressed in all Expressed in all parathyroid gland: 29.2 Expressed in all +CGN KIAA1319 ENSG00000143375 Cingulin 1 151510510-151538692 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017193, HPA027586, HPA027587, HPA027657 Enhanced Supported Plasma membrane
Cell Junctions Renal cancer:5.84e-10 (favourable) Expressed in all Tissue enhanced parathyroid gland: 73.4 small intestine: 61.9 Cell line enhanced CACO-2: 75.4;CAPAN-2: 52.0 +SNX27 KIAA0488, MGC20471, MY014 ENSG00000143376 Sorting nexin family member 27 1 151612065-151699091 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA045816 Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 19.1 Expressed in all +SETDB1 ESET, KG1T, KIAA0067, KMT1E, TDRD21 ENSG00000143379 SET domain bifurcated 1 1 150926263-150964744 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018142, HPA058484 Uncertain Enhanced Nucleoplasm
Cytosol Renal cancer:4.25e-4 (unfavourable), Liver cancer:8.88e-4 (unfavourable) Expressed in all Expressed in all testis: 46.3 Expressed in all +ADAMTSL4 DKFZP434K1772, TSRC1 ENSG00000143382 ADAMTS like 4 1 150549369-150560937 Disease related genes, Predicted secreted proteins Evidence at protein level HPA006279 Approved Approved Plasma membrane
Cytosol Renal cancer:4.35e-7 (unfavourable), Glioma:1.63e-4 (unfavourable), Colorectal cancer:1.86e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 88.9 lung: 32.3 Cell line enhanced ASC TERT1: 64.0;BEWO: 191.0;K-562: 60.1 +MCL1 BCL2L3, Mcl-1 ENSG00000143384 BCL2 family apoptosis regulator 1 150574551-150579738 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002781, HPA008455, HPA031125, CAB068195 Approved Enhanced Mitochondria Renal cancer:7.16e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 661.4 Cell line enriched 11 U-698: 3345.2 +CTSK CTSO, CTSO2, PKND, PYCD ENSG00000143387 Cathepsin K 1 150796208-150808323 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA050346 Supported Vesicles Renal cancer:7.12e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 575.0 Group enriched 6 ASC diff: 1592.3;ASC TERT1: 590.6;BJ hTERT+: 1576.7 +RFX5 ENSG00000143390 Regulatory factor X5 1 151340640-151347357 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018519 Supported Expressed in all Expressed in all lymph node: 85.6 Expressed in all +PI4KB PI4K-BETA, pi4K92, PIK4CB ENSG00000143393 Phosphatidylinositol 4-kinase beta 1 151291797-151327715 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006280, HPA006281, CAB022071 Approved Supported Golgi apparatus Pancreatic cancer:1.25e-5 (favourable), Liver cancer:2.97e-4 (unfavourable), Renal cancer:3.23e-4 (unfavourable), Thyroid cancer:6.78e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 102.7 Expressed in all +PIP5K1A ENSG00000143398 Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha 1 151197949-151249536 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA029366 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:4.16e-7 (unfavourable) Expressed in all Expressed in all testis: 67.8 Expressed in all +ANP32E LANP-L, LANPL, MGC5350 ENSG00000143401 Acidic nuclear phosphoprotein 32 family member E 1 150218417-150236156 Predicted intracellular proteins Evidence at protein level CAB021114, HPA063133, HPA067561 Supported Supported Nucleoplasm
Centrosome
Cytosol Renal cancer:3.82e-8 (unfavourable), Liver cancer:4.50e-5 (unfavourable) Expressed in all Expressed in all lymph node: 84.1 Expressed in all +MINDY1 FAM63A, FLJ11280, MINDY-1 ENSG00000143409 MINDY lysine 48 deubiquitinase 1 1 150996086-151008375 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028351, HPA028358, HPA061086 Approved Supported Nucleoplasm Renal cancer:3.43e-8 (favourable) Expressed in all Expressed in all thyroid gland: 79.1 Cell line enhanced T-47d: 46.6 +ANXA9 ANX31 ENSG00000143412 Annexin A9 1 150982017-150995634 Predicted intracellular proteins Evidence at protein level HPA028404, HPA028698 Enhanced Approved Nuclear speckles
Cytosol Renal cancer:8.74e-6 (favourable) Expressed in all Mixed thyroid gland: 35.3 Cell line enhanced CAPAN-2: 31.9;MCF7: 38.4;T-47d: 113.2 +SELENBP1 hSBP, hSP56, LPSB ENSG00000143416 Selenium binding protein 1 1 151364302-151372733 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005741, CAB008366, HPA011731 Enhanced Supported Nucleoli Head and neck cancer:6.63e-4 (favourable) Expressed in all Expressed in all rectum: 488.9 Cell line enhanced ASC diff: 97.2;HEL: 100.3;SK-BR-3: 194.4 +CERS2 FLJ10243, LASS2, SP260 ENSG00000143418 Ceramide synthase 2 1 150960583-150975004 Predicted membrane proteins Evidence at protein level HPA027262 Approved Supported Nuclear membrane
Endoplasmic reticulum Expressed in all Expressed in all liver: 410.7 Expressed in all +ENSA ARPP-19e, MGC4319, MGC78563, MGC8394 ENSG00000143420 Endosulfine alpha 1 150600851-150629612 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051294 Uncertain Approved Nucleus
Nucleoli
Microtubules
Cytosol Cervical cancer:8.24e-4 (favourable) Expressed in all Expressed in all esophagus: 267.3 Cell line enriched 12 U-698: 5502.7 +SEMA6C KIAA1869 ENSG00000143434 Semaphorin 6C 1 151131685-151146664 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA076150, HPA077625 Approved Nucleoplasm
Nucleoli fibrillar center
Plasma membrane
Cytosol Pancreatic cancer:3.06e-5 (favourable), Endometrial cancer:3.27e-4 (unfavourable) Expressed in all Tissue enhanced skeletal muscle: 111.3 testis: 33.8 Cell line enhanced AF22: 13.8;HUVEC TERT2: 20.6 +MRPL9 ENSG00000143436 Mitochondrial ribosomal protein L9 1 151759643-151763564 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA008579 Approved Supported Mitochondria Liver cancer:1.04e-7 (unfavourable), Renal cancer:1.44e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 60.5 Expressed in all +ARNT bHLHe2, HIF-1beta ENSG00000143437 Aryl hydrocarbon receptor nuclear translocator 1 150809705-150876768 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001759, CAB004318 Enhanced Supported Nucleus
Nuclear bodies Expressed in all Expressed in all ovary: 46.7 Cell line enriched 7 U-698: 274.9 +POGZ KIAA0461, ZNF280E, ZNF635m ENSG00000143442 Pogo transposable element with ZNF domain 1 151402724-151459465 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006800, HPA008781 Enhanced Enhanced Nucleoplasm Renal cancer:3.92e-5 (unfavourable), Urothelial cancer:4.40e-4 (favourable), Endometrial cancer:8.67e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 76.7 Expressed in all +C1orf56 FLJ20519, MENT ENSG00000143443 Chromosome 1 open reading frame 56 1 151047740-151051986 Predicted secreted proteins Evidence at protein level HPA037429, HPA037430 Enhanced Expressed in all Tissue enriched 7 testis: 48.5 thyroid gland: 6.8 Mixed +OAZ3 ENSG00000143450 Ornithine decarboxylase antizyme 3 1 151762899-151771334 Predicted intracellular proteins Evidence at protein level HPA030136 Supported Nucleoplasm Mixed Tissue enriched 13 testis: 197.6 prostate: 14.7 Mixed +HORMAD1 CT46, DKFZP434A1315 ENSG00000143452 HORMA domain containing 1 1 150698060-150720888 Predicted intracellular proteins Evidence at protein level HPA028346, HPA037850 Enhanced Approved Nucleoplasm
Nucleoli Tissue enhanced Tissue enriched 26 testis: 224.9 skin: 8.8 Cell line enhanced A549: 5.6;hTCEpi: 14.9;SiHa: 6.8;THP-1: 8.3;U-2 OS: 4.1 +GOLPH3L GPP34R ENSG00000143457 Golgi phosphoprotein 3 like 1 150646225-150697144 Predicted intracellular proteins Evidence at protein level HPA028558 Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all thyroid gland: 51.4 Cell line enriched 6 U-698: 294.2 +GABPB2 MGC29891 ENSG00000143458 GA binding protein transcription factor beta subunit 2 1 151070578-151125542 Predicted intracellular proteins Evidence at protein level HPA028471, HPA058483 Uncertain Supported Nucleoplasm
Cytosol Expressed in all Mixed testis: 20.1 Mixed +SYT14 FLJ34198, sytXIV ENSG00000143469 Synaptotagmin 14 1 209938174-210171389 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036963 Supported Vesicles Tissue enhanced Group enriched 5 cerebral cortex: 3.0;testis: 6.7;thyroid gland: 9.8 adrenal gland: 1.3 Cell line enhanced BJ hTERT+: 10.5;SCLC-21H: 7.8;TIME: 8.9;U-138 MG: 7.9 +KCNH1 eag, eag1, h-eag, Kv10.1 ENSG00000143473 Potassium voltage-gated channel subfamily H member 1 1 210676823-211134180 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA014551, HPA019445 Enhanced Approved Vesicles Not detected Tissue enriched 6 cerebral cortex: 6.2 testis: 1.0 Cell line enhanced RH-30: 4.9;SH-SY5Y: 6.8;SK-MEL-30: 4.8;T-47d: 4.3 +DTL CDT2, DCAF2, L2DTL, RAMP ENSG00000143476 Denticleless E3 ubiquitin protein ligase homolog 1 212035553-212107400 Predicted intracellular proteins Evidence at protein level HPA028016, HPA032023, HPA032031 Uncertain Enhanced Nucleus
Cytosol Renal cancer:1.71e-9 (unfavourable), Liver cancer:4.41e-5 (unfavourable) Expressed in all Tissue enhanced testis: 23.8 bone marrow: 8.2 Mixed +DYRK3 hYAK3-2, RED, REDK ENSG00000143479 Dual specificity tyrosine phosphorylation regulated kinase 3 1 206635536-206684419 Enzymes, Predicted intracellular proteins Evidence at protein level HPA075041 Supported Nucleoplasm
Cytosol Renal cancer:9.41e-7 (unfavourable) Expressed in all Tissue enhanced testis: 86.7 gallbladder: 23.2 Cell line enhanced hTERT-HME1: 56.1 +EIF2D LGTN ENSG00000143486 Eukaryotic translation initiation factor 2D 1 206571292-206612463 Predicted intracellular proteins Evidence at protein level HPA028220 Approved Approved Nuclear bodies
Cytosol Renal cancer:1.74e-4 (unfavourable) Expressed in all Expressed in all ovary: 74.1 Expressed in all +INTS7 C1orf73, DKFZP434B168, INT7 ENSG00000143493 Integrator complex subunit 7 1 211940399-212035542 Predicted intracellular proteins Evidence at protein level HPA072611 Supported Nuclear bodies Renal cancer:1.42e-5 (unfavourable) Expressed in all Tissue enhanced testis: 38.8 thyroid gland: 11.2 Expressed in all +VASH2 FLJ12505 ENSG00000143494 Vasohibin 2 1 212950520-212992037 Predicted intracellular proteins Evidence at protein level HPA045820 Approved Cytosol Tissue enhanced Tissue enhanced testis: 11.3 appendix,esophagus,prostate: 4.5 Cell line enhanced AN3-CA: 27.4;NTERA-2: 46.2;RH-30: 131.2 +TAF1A SL1, TAFI48 ENSG00000143498 TATA-box binding protein associated factor, RNA polymerase I subunit A 1 222557902-222589933 Predicted intracellular proteins Evidence at protein level HPA054334 Approved Supported Nucleoplasm Cervical cancer:9.26e-6 (unfavourable) Expressed in all Mixed testis: 12.0 Expressed in all +SMYD2 HSKM-B, KMT3C, ZMYND14 ENSG00000143499 SET and MYND domain containing 2 1 214281102-214337131 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029023 Uncertain Approved Intermediate filaments
Mitochondria
Cytosol Cervical cancer:1.53e-5 (unfavourable), Renal cancer:8.68e-4 (favourable) Expressed in all Expressed in all heart muscle: 153.5 Expressed in all +SUSD4 FLJ10052 ENSG00000143502 Sushi domain containing 4 1 223220819-223364202 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058296 Uncertain Approved Vesicles Endometrial cancer:4.28e-4 (unfavourable) Mixed Tissue enhanced esophagus: 42.4 cerebral cortex: 38.5 Cell line enriched 5 SCLC-21H: 46.1 +DUSP10 MKP-5, MKP5 ENSG00000143507 Dual specificity phosphatase 10 1 221701424-221742176 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016758 Approved Supported Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:3.69e-4 (unfavourable), Liver cancer:5.42e-4 (favourable) Expressed in all Mixed liver: 16.7 Cell line enhanced HaCaT: 86.1 +HHIPL2 FLJ13840, KIAA1822L ENSG00000143512 HHIP like 2 1 222522258-222548103 Predicted secreted proteins Evidence at protein level HPA059673 Enhanced Uncertain Mitochondria
Cytosol Lung cancer:4.64e-4 (unfavourable) Mixed Tissue enhanced testis: 9.0;thyroid gland: 3.4 prostate: 1.4 Cell line enhanced A549: 3.8;Hep G2: 4.0;RH-30: 20.6;U-87 MG: 10.5 +TP53BP2 53BP2, ASPP2, PPP1R13A ENSG00000143514 Tumor protein p53 binding protein 2 1 223779899-223845972 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA021603, HPA050429 Supported Enhanced Cell Junctions
Cytosol Expressed in all Expressed in all thyroid gland: 34.6 Mixed +ATP8B2 ATPID, KIAA1137 ENSG00000143515 ATPase phospholipid transporting 8B2 1 154325553-154351307 Enzymes, Predicted membrane proteins Evidence at protein level HPA046680 Approved Urothelial cancer:5.29e-5 (unfavourable), Pancreatic cancer:1.60e-4 (favourable) Expressed in all Mixed smooth muscle: 61.1 Mixed +FLG2 IFPS ENSG00000143520 Filaggrin family member 2 1 152348735-152360006 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028699 Approved Tissue enriched Tissue enriched 14 skin: 578.9 breast: 42.8 Not detected +CRNN C1orf10, SEP53 ENSG00000143536 Cornulin 1 152409243-152414263 Predicted intracellular proteins Evidence at protein level HPA024343, CAB026182 Enhanced Group enriched Tissue enriched 20 esophagus: 4518.8 tonsil: 225.3 Not detected +ADAM15 MDC15 ENSG00000143537 ADAM metallopeptidase domain 15 1 155050566-155062775 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011633, HPA072878 Uncertain Uncertain Vesicles Renal cancer:5.64e-9 (unfavourable), Glioma:3.49e-5 (unfavourable), Liver cancer:3.49e-4 (unfavourable) Expressed in all Expressed in all skin: 72.6 Cell line enhanced PC-3: 305.3 +JTB hJT, PAR ENSG00000143543 Jumping translocation breakpoint 1 153974269-153977688 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA006514 Approved Approved Vesicles
Actin filaments Renal cancer:6.65e-9 (unfavourable), Ovarian cancer:7.87e-4 (favourable) Expressed in all Expressed in all epididymis: 116.4 Expressed in all +RAB13 ENSG00000143545 RAB13, member RAS oncogene family 1 153981617-153986358 Predicted intracellular proteins Evidence at protein level HPA003996 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all prostate: 150.3 Mixed +S100A8 60B8AG, CAGA, CFAG, CGLA, MRP8, P8 ENSG00000143546 S100 calcium binding protein A8 1 153390032-153391188 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002791, HPA024372 Enhanced Supported Intermediate filaments Renal cancer:8.94e-7 (unfavourable) Expressed in all Group enriched 9 bone marrow: 14915.7;esophagus: 12755.4;tonsil: 4867.3 appendix: 1232.5 Group enriched 28 hTCEpi: 103.6;SK-BR-3: 396.8;THP-1: 195.3 +TPM3 NEM1, TRK ENSG00000143549 Tropomyosin 3 1 154155304-154194648 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000261, HPA009066, HPA047089, HPA053624 Approved Approved Actin filaments
Cytosol Liver cancer:6.73e-6 (unfavourable), Ovarian cancer:2.39e-5 (favourable), Renal cancer:3.12e-5 (unfavourable), Pancreatic cancer:3.65e-4 (unfavourable), Lung cancer:4.01e-4 (unfavourable) Expressed in all Tissue enriched 7 skeletal muscle: 2869.3 bone marrow: 428.4 Expressed in all +NUP210L ENSG00000143552 Nucleoporin 210 like 1 153992685-154155116 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA047195, HPA064245, HPA066707 Enhanced Approved Nuclear bodies Not detected Tissue enriched 100 testis: 47.8 seminal vesicle,smooth muscle,thyroid gland: 0.4 Cell line enriched 42 MCF7: 12.0 +SNAPIN BLOC1S7, BORCS3, SNAPAP ENSG00000143553 SNAP associated protein 1 153658654-153661830 Predicted intracellular proteins, Transporters Evidence at protein level HPA046974 Approved Approved Nucleoli
Golgi apparatus Renal cancer:5.42e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 42.3 Expressed in all +SLC27A3 ACSVL3, FATP3, MGC4365 ENSG00000143554 Solute carrier family 27 member 3 1 153774354-153780157 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA006935, HPA067508 Uncertain Supported Endoplasmic reticulum Pancreatic cancer:5.23e-4 (favourable), Renal cancer:6.33e-4 (unfavourable) Expressed in all Tissue enhanced epididymis: 43.9 lung: 20.9 Cell line enhanced ASC diff: 42.9;MCF7: 27.0 +S100A7 PSOR1, S100A7c ENSG00000143556 S100 calcium binding protein A7 1 153457744-153460701 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001453, HPA006997, CAB033766 Enhanced Group enriched Group enriched 6 skin: 326.2;tonsil: 885.9 esophagus: 95.9 Cell line enhanced HaCaT: 5.4;SK-BR-3: 10.6 +UBAP2L KIAA0144, NICE-4 ENSG00000143569 Ubiquitin associated protein 2 like 1 154220179-154271510 Predicted intracellular proteins Evidence at protein level HPA035068 Approved Approved Nuclear speckles
Cytosol Renal cancer:2.89e-5 (unfavourable), Liver cancer:4.65e-5 (unfavourable) Expressed in all Expressed in all testis: 122.8 Expressed in all +SLC39A1 ZIP1, ZIRTL ENSG00000143570 Solute carrier family 39 member 1 1 153959099-153968184 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA016506 Uncertain Cytosol Liver cancer:4.12e-7 (unfavourable), Head and neck cancer:5.26e-5 (unfavourable), Cervical cancer:4.83e-4 (unfavourable) Expressed in all Expressed in all placenta: 134.2 Expressed in all +HAX1 HCLSBP1, HS1BP1 ENSG00000143575 HCLS1 associated protein X-1 1 154272511-154275875 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055141, HPA075289 Approved Supported Mitochondria Renal cancer:1.34e-5 (unfavourable) Expressed in all Expressed in all testis: 114.9 Expressed in all +CREB3L4 AIbZIP, ATCE1, CREB3, CREB4, hJAL ENSG00000143578 CAMP responsive element binding protein 3 like 4 1 153967534-153974363 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA038122 Enhanced Approved Nucleoplasm
Nuclear membrane
Mitochondria Endometrial cancer:7.21e-4 (favourable) Group enriched Expressed in all prostate: 170.5 Expressed in all +EFNA3 Ehk1-L, EPLG3, LERK3 ENSG00000143590 Ephrin A3 1 155078872-155087538 Predicted membrane proteins, RAS pathway related proteins Evidence at protein level CAB010494 Uncertain Renal cancer:9.66e-10 (unfavourable), Liver cancer:2.46e-4 (unfavourable) Expressed in all Tissue enhanced skin: 51.3 cerebral cortex: 17.0 Cell line enhanced HAP1: 19.5;SCLC-21H: 32.5;T-47d: 24.4 +AQP10 ENSG00000143595 Aquaporin 10 1 154321090-154325325 Predicted membrane proteins, Transporters Evidence at protein level HPA065947 Enhanced Not detected Group enriched 8 duodenum: 68.4;small intestine: 48.7 fallopian tube: 7.2 Group enriched 27 HEL: 16.1;HMC-1: 6.3;K-562: 18.7;SH-SY5Y: 5.0 +KCNN3 hSK3, KCa2.3, SKCA3 ENSG00000143603 Potassium calcium-activated channel subfamily N member 3 1 154697455-154870280 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA017990, HPA057127 Uncertain Approved Nucleoplasm Renal cancer:1.97e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 25.4 fallopian tube: 9.4 Cell line enhanced Daudi: 28.1;HMC-1: 23.0;Karpas-707: 46.9;U-266/70: 47.5 +C1orf43 DKFZp586G1722, NICE-3 ENSG00000143612 Chromosome 1 open reading frame 43 1 154206706-154220637 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010725 Approved Liver cancer:6.57e-4 (unfavourable) Expressed in all Expressed in all kidney: 194.9 Expressed in all +GATAD2B P66beta ENSG00000143614 GATA zinc finger domain containing 2B 1 153789030-153923360 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA017015 Approved Enhanced Nucleoplasm Colorectal cancer:1.30e-4 (unfavourable), Renal cancer:3.08e-4 (unfavourable) Expressed in all Expressed in all testis: 19.7 Expressed in all +ILF2 NF45 ENSG00000143621 Interleukin enhancer binding factor 2 1 153661788-153671048 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007484 Supported Enhanced Nucleus
Nucleoli Liver cancer:5.71e-8 (unfavourable), Renal cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all testis: 211.7 Expressed in all +RIT1 MGC125864, MGC125865, RIBB, RIT, ROC1 ENSG00000143622 Ras like without CAAX 1 1 155897808-155911404 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053249 Approved Liver cancer:8.64e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 50.5 Expressed in all +INTS3 C1orf60, FLJ21919, INT3, SOSS-A ENSG00000143624 Integrator complex subunit 3 1 153728067-153774808 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA074391 Approved Supported Nucleus
Nucleoli Renal cancer:1.34e-6 (unfavourable), Pancreatic cancer:5.42e-4 (favourable) Expressed in all Expressed in all fallopian tube: 16.5 Expressed in all +PKLR ENSG00000143627 Pyruvate kinase, liver and RBC 1 155289839-155301434 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006653, CAB034376, CAB034378 Enhanced Approved Endoplasmic reticulum
Golgi apparatus Tissue enriched Tissue enhanced kidney: 14.0;liver: 26.4 bone marrow: 7.8 Cell line enriched 16 K-562: 72.0 +HCN3 KIAA1535 ENSG00000143630 Hyperpolarization activated cyclic nucleotide gated potassium channel 3 1 155277583-155289848 Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level HPA026584 Approved Urothelial cancer:6.93e-4 (favourable), Renal cancer:7.49e-4 (unfavourable) Expressed in all Mixed cerebral cortex,skin: 2.9 Cell line enhanced K-562: 5.7 +FLG ENSG00000143631 Filaggrin 1 152302175-152325203 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002210, HPA027505, HPA030188, HPA030189 Enhanced Supported Vesicles Tissue enriched Tissue enriched 26 skin: 548.3 breast: 21.1 Cell line enhanced HaCaT: 8.9;NTERA-2: 3.1;U-2 OS: 2.5;U-2197: 2.4 +ACTA1 ACTA, NEM3 ENSG00000143632 Actin, alpha 1, skeletal muscle 1 229431245-229434098 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000045, HPA041264, HPA041271 Enhanced Group enriched Tissue enriched 14 skeletal muscle: 45978.0 heart muscle: 3193.1 Cell line enriched 30 BEWO: 452.7 +C1orf131 DKFZp547B1713 ENSG00000143633 Chromosome 1 open reading frame 131 1 231223763-231241187 Predicted intracellular proteins Evidence at protein level HPA028452, HPA029920 Enhanced Enhanced Nucleus
Nucleoli
Cytosol Renal cancer:2.64e-9 (unfavourable), Urothelial cancer:9.84e-4 (favourable) Expressed in all Expressed in all duodenum: 21.6 Expressed in all +GALNT2 GalNAc-T2 ENSG00000143641 Polypeptide N-acetylgalactosaminyltransferase 2 1 230057990-230282124 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA011222 Supported Enhanced Golgi apparatus Renal cancer:2.79e-13 (unfavourable), Lung cancer:8.48e-8 (unfavourable), Cervical cancer:1.22e-6 (unfavourable) Expressed in all Expressed in all ovary: 48.5 Expressed in all +TTC13 FLJ22584 ENSG00000143643 Tetratricopeptide repeat domain 13 1 230906243-230978875 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018022, HPA051558 Uncertain Approved Nucleoplasm Renal cancer:1.60e-11 (unfavourable), Pancreatic cancer:4.59e-5 (favourable), Head and neck cancer:7.66e-4 (favourable) Expressed in all Expressed in all lymph node: 23.0 Expressed in all +SCCPDH CGI-49, NET11 ENSG00000143653 Saccharopine dehydrogenase (putative) 1 246724047-246768137 Predicted membrane proteins Evidence at protein level HPA050775 Uncertain Approved Vesicles Expressed in all Expressed in all testis: 241.5 Mixed +LYST CHS, CHS1 ENSG00000143669 Lysosomal trafficking regulator 1 235661041-235883640 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053366, HPA055725 Approved Nucleoplasm
Plasma membrane
Microtubule organizing center Renal cancer:5.27e-5 (unfavourable) Expressed in all Mixed bone marrow: 20.9 Cell line enhanced HDLM-2: 28.5;THP-1: 66.9;U-937: 29.8 +MAP3K21 KIAA1804, MLK4 ENSG00000143674 Mitogen-activated protein kinase kinase kinase 21 1 233327768-233385148 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007636 Uncertain Approved Plasma membrane
Cytosol Mixed Mixed testis: 17.8 Cell line enhanced HEK 293: 25.2 +CEP170 FAM68A, KAB, KIAA0470 ENSG00000143702 Centrosomal protein 170 1 243124428-243255348 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042151, HPA045597, HPA045787 Uncertain Enhanced Plasma membrane
Centrosome
Cytosol Renal cancer:1.30e-9 (unfavourable) Expressed in all Tissue enhanced testis: 130.5 cerebral cortex: 44.7 Expressed in all +ACP1 HAAP, LMW-PTP, LMWPTP ENSG00000143727 Acid phosphatase 1, soluble 2 264140-278283 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016754 Approved Approved Nucleus
Cytosol Liver cancer:6.67e-6 (unfavourable), Melanoma:3.04e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 128.8 Expressed in all +SNAP47 C1orf142, SNAP-47, SVAP1 ENSG00000143740 Synaptosome associated protein 47 1 227728539-227781231 Predicted intracellular proteins Evidence at protein level HPA028167 Enhanced Approved Cytosol Expressed in all Expressed in all testis: 56.6 Expressed in all +SRP9 ENSG00000143742 Signal recognition particle 9 1 225777813-225790466 Predicted intracellular proteins, Transporters Evidence at protein level Expressed in all Expressed in all cerebral cortex: 340.2 Expressed in all +NVL NVL2 ENSG00000143748 Nuclear VCP-like 1 224227334-224330387 Predicted intracellular proteins Evidence at protein level HPA028207, HPA028219, HPA028224, HPA028654 Enhanced Enhanced Nucleoli Renal cancer:4.10e-11 (unfavourable), Liver cancer:5.77e-5 (unfavourable), Lung cancer:2.95e-4 (favourable) Expressed in all Expressed in all skin: 18.7 Expressed in all +SDE2 C1orf55, FLJ35382 ENSG00000143751 SDE2 telomere maintenance homolog 1 225982702-225999331 Predicted intracellular proteins Evidence at protein level HPA028467, HPA031255, HPA031256 Approved Approved Nuclear speckles
Golgi apparatus
Plasma membrane
Cytosol Expressed in all Expressed in all thyroid gland: 21.1 Expressed in all +DEGS1 DEGS-1, Des-1, DES1, FADS7, MLD ENSG00000143753 Delta 4-desaturase, sphingolipid 1 1 224175756-224193441 Enzymes, Predicted membrane proteins Evidence at protein level HPA076422 Supported Mitochondria Renal cancer:6.83e-7 (unfavourable), Liver cancer:4.29e-5 (unfavourable), Endometrial cancer:7.74e-5 (unfavourable), Urothelial cancer:2.53e-4 (unfavourable) Expressed in all Expressed in all skin: 616.3 Expressed in all +FBXO28 CENP-30, Fbx28, FLJ10766, KIAA0483 ENSG00000143756 F-box protein 28 1 224114087-224162047 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003289 Supported Nucleus
Focal adhesion sites Expressed in all Expressed in all parathyroid gland,skin: 25.0 Expressed in all +ARF1 ENSG00000143761 ADP ribosylation factor 1 1 228082660-228099212 Predicted intracellular proteins Evidence at protein level CAB007742 Uncertain Approved Plasma membrane
Cytosol Head and neck cancer:1.55e-4 (unfavourable) Expressed in all Expressed in all placenta: 384.2 Expressed in all +LEFTY2 EBAF, LEFTA, LEFTYA, TGFB4 ENSG00000143768 Left-right determination factor 2 1 225936598-225941489 Disease related genes, Predicted secreted proteins Evidence at protein level CAB025801, HPA047883, HPA056210 Approved Tissue enriched Group enriched 6 endometrium: 264.3;smooth muscle: 57.0 ovary: 26.0 Group enriched 12 HDLM-2: 8.7;NTERA-2: 40.5;RPMI-8226: 31.4 +CNIH4 HSPC163 ENSG00000143771 Cornichon family AMPA receptor auxiliary protein 4 1 224356850-224379459 Predicted membrane proteins Evidence at protein level HPA044268 Approved Renal cancer:4.27e-6 (unfavourable), Head and neck cancer:1.72e-4 (unfavourable), Pancreatic cancer:4.61e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 27.4 Expressed in all +ITPKB IP3-3KB, IP3KB ENSG00000143772 Inositol-trisphosphate 3-kinase B 1 226631690-226739323 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA030273, HPA072923 Uncertain Approved Nucleus Head and neck cancer:1.72e-5 (favourable), Lung cancer:6.65e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 61.6 Cell line enhanced SK-MEL-30: 36.3 +GUK1 ENSG00000143774 Guanylate kinase 1 1 228139962-228148984 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028118, HPA048587 Approved Uncertain Nucleoplasm
Cytosol Renal cancer:8.85e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 264.8 Expressed in all +CDC42BPA FLJ23347, KIAA0451, MRCK, MRCKA, PK428 ENSG00000143776 CDC42 binding protein kinase alpha 1 226989865-227318474 Enzymes, Predicted intracellular proteins Evidence at protein level CAB070414, HPA071252 Approved Approved Intermediate filaments Expressed in all Expressed in all testis: 45.2 Mixed +CNIH3 CNIH-3, FLJ38993 ENSG00000143786 Cornichon family AMPA receptor auxiliary protein 3 1 224434660-224740549 Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced cerebral cortex: 14.7 testis: 4.2 Cell line enhanced hTEC/SVTERT24-B: 46.6;NTERA-2: 17.2;U-266/70: 18.9;U-87 MG: 53.6 +C1orf35 MGC4174, MMTAG2 ENSG00000143793 Chromosome 1 open reading frame 35 1 228100726-228105411 Predicted intracellular proteins Evidence at protein level HPA046175 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Renal cancer:1.79e-6 (unfavourable), Ovarian cancer:7.38e-4 (favourable), Colorectal cancer:7.71e-4 (unfavourable) Expressed in all Expressed in all skin: 14.3 Expressed in all +MBOAT2 FLJ14415, FLJ90298, OACT2 ENSG00000143797 Membrane bound O-acyltransferase domain containing 2 2 8852690-9003813 Enzymes, Predicted membrane proteins Evidence at protein level HPA014836 Uncertain Approved Vesicles Endometrial cancer:2.13e-9 (unfavourable), Urothelial cancer:5.32e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 50.1 cerebral cortex: 29.7 Mixed +PARP1 ADPRT, PARP, PPOL ENSG00000143799 Poly(ADP-ribose) polymerase 1 1 226360691-226408079 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727 Supported Supported Enhanced Nucleus Renal cancer:1.35e-5 (unfavourable), Liver cancer:3.40e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 198.4 Expressed in all +PSEN2 AD3L, AD4, PS2, STM2 ENSG00000143801 Presenilin 2 1 226870184-226896105 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB013634, HPA038005 Supported Nucleus Expressed in all Expressed in all parathyroid gland: 28.8 Mixed +PYCR2 P5CR2 ENSG00000143811 Pyrroline-5-carboxylate reductase family member 2 1 225919877-225924340 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA056873 Approved Approved Mitochondria Renal cancer:1.42e-6 (unfavourable), Colorectal cancer:5.02e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 71.9 Expressed in all +LBR DHCR14B, TDRD18 ENSG00000143815 Lamin B receptor 1 225401502-225428925 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049840, HPA062236 Enhanced Enhanced Nuclear membrane Liver cancer:7.30e-4 (unfavourable) Expressed in all Expressed in all lymph node: 98.6 Expressed in all +WNT9A WNT14 ENSG00000143816 Wnt family member 9A 1 227918656-227947898 Plasma proteins, Predicted secreted proteins Evidence at transcript level Ovarian cancer:1.06e-4 (unfavourable) Mixed Mixed heart muscle: 7.2 Cell line enhanced HaCaT: 14.4;RH-30: 16.0;SCLC-21H: 17.7;SiHa: 15.7 +EPHX1 EPHX ENSG00000143819 Epoxide hydrolase 1 1 225810092-225845563 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020593, HPA048847 Enhanced Lung cancer:7.02e-5 (favourable), Prostate cancer:1.32e-4 (favourable) Tissue enriched Expressed in all adrenal gland: 1085.6 Cell line enhanced ASC diff: 821.1;SiHa: 629.7 +REN ENSG00000143839 Renin 1 204154819-204190324 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005131, CAB025903 Approved Renal cancer:6.45e-5 (unfavourable) Tissue enriched Tissue enhanced kidney: 51.2;placenta: 21.0 endometrium: 8.9 Cell line enhanced BJ: 1.7;HMC-1: 2.3;SK-BR-3: 1.4 +SOX13 ICA12, MGC117216, Sox-13 ENSG00000143842 SRY-box 13 1 204073115-204127743 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051790, HPA054843 Enhanced Nucleoplasm Colorectal cancer:6.49e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 53.8 Cell line enhanced SK-BR-3: 103.3 +ETNK2 EKI2, FLJ10761 ENSG00000143845 Ethanolamine kinase 2 1 204131062-204152003 Enzymes, Predicted intracellular proteins Evidence at protein level HPA057167 Enhanced Glioma:3.43e-4 (unfavourable), Renal cancer:6.50e-4 (favourable) Expressed in all Tissue enhanced kidney: 110.6;liver: 120.7;testis: 143.1 ovary: 43.4 Mixed +PPFIA4 ENSG00000143847 PTPRF interacting protein alpha 4 1 203026498-203078740 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053419, HPA054132 Enhanced Renal cancer:1.73e-8 (unfavourable) Mixed Tissue enhanced cerebral cortex: 24.8;heart muscle: 14.5 skeletal muscle: 6.5 Cell line enhanced RH-30: 13.1;U-87 MG: 12.1 +PLEKHA6 KIAA0969, PEPP3 ENSG00000143850 Pleckstrin homology domain containing A6 1 204218851-204377665 Predicted intracellular proteins Evidence at protein level HPA028152, HPA054311 Approved Supported Vesicles
Cell Junctions
Microtubule organizing center Urothelial cancer:3.57e-4 (favourable) Expressed in all Mixed stomach: 40.6 Cell line enhanced BEWO: 88.4;CAPAN-2: 75.9;PC-3: 64.5;RT4: 62.5 +PTPN7 HEPTP, LC-PTP ENSG00000143851 Protein tyrosine phosphatase, non-receptor type 7 1 202147013-202161588 Enzymes, Predicted intracellular proteins Evidence at protein level CAB009530, HPA019118 Approved Renal cancer:2.42e-8 (unfavourable), Endometrial cancer:1.52e-4 (favourable), Head and neck cancer:1.84e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 25.2;lymph node: 24.3 tonsil: 19.3 Cell line enhanced HEL: 48.4;HL-60: 93.9;HMC-1: 132.7;U-937: 65.7 +SYT2 ENSG00000143858 Synaptotagmin 2 1 202590596-202710417 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA030372, HPA063655 Enhanced Supported Approved Vesicles Tissue enriched Tissue enhanced adrenal gland: 1.8;cerebral cortex: 2.1 epididymis,testis: 1.0 Cell line enhanced AF22: 8.4;NTERA-2: 5.8;U-2 OS: 1.8 +ARL8A ARL10B, FLJ45195, Gie2 ENSG00000143862 ADP ribosylation factor like GTPase 8A 1 202133404-202144743 Predicted intracellular proteins Evidence at protein level HPA038759, HPA040515, HPA045924 Approved Colorectal cancer:3.08e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 113.6 Expressed in all +OSR1 ODD ENSG00000143867 Odd-skipped related transciption factor 1 2 19351485-19358653 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA015525 Uncertain Mixed Mixed adipose tissue: 22.1 Cell line enriched 14 U-2197: 92.8 +GDF7 BMP12 ENSG00000143869 Growth differentiation factor 7 2 20666664-20679245 Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced seminal vesicle: 29.5 endometrium: 11.5 Cell line enhanced HAP1: 1.7;Hep G2: 2.8;RT4: 6.2;SH-SY5Y: 3.3 +PDIA6 ERp5, P5, TXNDC7 ENSG00000143870 Protein disulfide isomerase family A member 6 2 10783391-10837977 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB034347, HPA034652, HPA034653 Enhanced Supported Endoplasmic reticulum
Cytosol Renal cancer:2.51e-6 (unfavourable), Liver cancer:3.63e-5 (unfavourable), Head and neck cancer:1.20e-4 (unfavourable), Cervical cancer:1.80e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 591.9 Expressed in all +RHOB ARH6, ARHB, MST081, RhoB, RHOH6 ENSG00000143878 Ras homolog family member B 2 20447074-20449445 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.23e-4 (favourable) Expressed in all Expressed in all adrenal gland: 710.5 Cell line enhanced RPTEC TERT1: 344.8;SK-BR-3: 419.9 +ATP6V1C2 ATP6C2, VMA5 ENSG00000143882 ATPase H+ transporting V1 subunit C2 2 10721649-10785110 Predicted intracellular proteins, Transporters Evidence at protein level HPA034734, HPA067305 Approved Uncertain Mitochondria Renal cancer:1.12e-11 (unfavourable) Mixed Tissue enhanced cervix, uterine: 83.9;epididymis: 99.0;skin: 123.7 placenta: 55.1 Group enriched 9 BEWO: 71.4;SK-BR-3: 20.0 +HNRNPLL HNRPLL ENSG00000143889 Heterogeneous nuclear ribonucleoprotein L like 2 38561978-38603586 Predicted intracellular proteins Evidence at protein level HPA046084 Approved Approved Nucleus
Mitochondria
Cytosol Liver cancer:1.22e-4 (unfavourable) Expressed in all Expressed in all testis: 37.5 Mixed +GALM ENSG00000143891 Galactose mutarotase 2 38665910-38741237 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035472, HPA035473, HPA064835 Enhanced Approved Nucleoplasm Renal cancer:9.06e-5 (favourable), Urothelial cancer:1.32e-4 (favourable) Expressed in all Expressed in all kidney: 118.1 Mixed +CAMKMT C2orf34, CLNMT ENSG00000143919 Calmodulin-lysine N-methyltransferase 2 44361950-44772592 Enzymes, Predicted intracellular proteins Evidence at protein level HPA067912 Supported Nucleus Glioma:5.39e-4 (favourable) Expressed in all Expressed in all testis: 24.3 Expressed in all +ABCG8 GBD4 ENSG00000143921 ATP binding cassette subfamily G member 8 2 43838964-43878466 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA019556 Uncertain Approved Vesicles Tissue enriched Group enriched 25 duodenum: 50.0;liver: 34.0;small intestine: 55.5 gallbladder: 1.8 Cell line enriched 44 Hep G2: 6.9 +EML4 C2orf2, ELP120, ROPP120 ENSG00000143924 Echinoderm microtubule associated protein like 4 2 42169350-42332548 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA036687, HPA036688, HPA065337 Enhanced Supported Intermediate filaments
Microtubules
Cytosol Expressed in all Mixed placenta: 50.5 Expressed in all +CALM2 CAMII, PHKD ENSG00000143933 Calmodulin 2 2 47160082-47176601 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level CAB007790, HPA044999 Approved Thyroid cancer:1.94e-5 (favourable), Liver cancer:8.35e-5 (unfavourable), Endometrial cancer:4.84e-4 (unfavourable), Breast cancer:5.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1533.3 Expressed in all +CHAC2 ENSG00000143942 ChaC cation transport regulator homolog 2 2 53767792-53775196 Predicted intracellular proteins Evidence at protein level HPA049235 Approved Approved Cytosol Liver cancer:3.80e-7 (unfavourable) Expressed in all Mixed testis: 9.8 Expressed in all +RPS27A S27A, Uba80, UBCEP80 ENSG00000143947 Ribosomal protein S27a 2 55231903-55235853 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level CAB033319, HPA041344, HPA049132, HPA054087 Supported Approved Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:2.60e-6 (unfavourable), Liver cancer:2.26e-4 (unfavourable) Expressed in all Expressed in all ovary: 3413.3 Expressed in all +WDPCP BBS15, C2orf86, fritz, hFrtz ENSG00000143951 WD repeat containing planar cell polarity effector 2 63121383-63827843 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044144 Uncertain Approved Cell Junctions Mixed Mixed testis: 11.4 Expressed in all +VPS54 HCC8, PPP1R164 ENSG00000143952 VPS54, GARP complex subunit 2 63892146-64019072 Predicted intracellular proteins Evidence at protein level HPA055894, HPA067981, HPA070582 Enhanced Nucleoplasm
Golgi apparatus Pancreatic cancer:2.03e-4 (favourable), Liver cancer:2.47e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 59.8 Expressed in all +REG3G LPPM429, PAP1B, UNQ429 ENSG00000143954 Regenerating family member 3 gamma 2 79025686-79028505 Predicted secreted proteins Evidence at protein level HPA047894, HPA048334, HPA060705 Uncertain Approved Cytosol Tissue enriched Group enriched 15 epididymis: 201.5;testis: 107.2 pancreas: 10.0 Not detected +ASXL2 ASXH2, FLJ10898, KIAA1685 ENSG00000143970 Additional sex combs like 2, transcriptional regulator 2 25733753-25878516 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034646, HPA058040 Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 26.6 Expressed in all +ETAA1 ETAA16 ENSG00000143971 Ewing tumor associated antigen 1 2 67397319-67410545 Predicted intracellular proteins Evidence at protein level HPA035048, HPA035049 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland,thyroid gland: 15.7 Expressed in all +SNRPG Sm-G ENSG00000143977 Small nuclear ribonucleoprotein polypeptide G 2 70281362-70293771 Predicted intracellular proteins Evidence at protein level HPA064152, HPA067814 Enhanced Approved Nucleoplasm Renal cancer:1.08e-6 (unfavourable) Expressed in all Expressed in all epididymis: 114.2 Expressed in all +ABHD1 FLJ36128, LABH1 ENSG00000143994 Abhydrolase domain containing 1 2 27123789-27130812 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA044390 Uncertain Mixed Tissue enriched 17 testis: 30.0 liver: 1.7 Cell line enhanced RPMI-8226: 1.1;T-47d: 3.0;U-266/70: 2.4;U-266/84: 1.9 +MEIS1 ENSG00000143995 Meis homeobox 1 2 66433452-66573869 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level CAB011521, HPA056000, HPA058641 Approved Supported Nucleoplasm Head and neck cancer:2.70e-5 (favourable), Renal cancer:1.69e-4 (unfavourable) Tissue enhanced Expressed in all endometrium: 92.6 Cell line enhanced BJ hTERT+: 37.0;SH-SY5Y: 30.4 +TRIM43B ENSG00000144010 Tripartite motif containing 43B 2 95476967-95484731 Predicted intracellular proteins No evidence HPA042223, HPA042772 Uncertain Not detected Not detected testis: 0.6 Not detected +TRIM43 TRIM43A ENSG00000144015 Tripartite motif containing 43 2 95592018-95599778 Predicted intracellular proteins Evidence at protein level HPA042223, HPA042772 Uncertain Not detected Not detected testis: 0.7 Not detected +CIAO1 CIA1, WDR39 ENSG00000144021 Cytosolic iron-sulfur assembly component 1 2 96266132-96273349 Predicted intracellular proteins Evidence at protein level HPA017882 Uncertain Approved Nucleoplasm
Cytosol Endometrial cancer:4.13e-5 (unfavourable), Liver cancer:1.14e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 40.4 Expressed in all +ZNF514 FLJ14457 ENSG00000144026 Zinc finger protein 514 2 95147330-95165413 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA028974 Approved Approved Nucleoplasm
Nuclear bodies Expressed in all Expressed in all epididymis: 32.8 Expressed in all +SNRNP200 ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD ENSG00000144028 Small nuclear ribonucleoprotein U5 subunit 200 2 96274336-96305515 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029321 Approved Supported Nucleoplasm Endometrial cancer:3.89e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 116.4 Expressed in all +MRPS5 MRP-S5, S5mt ENSG00000144029 Mitochondrial ribosomal protein S5 2 95087207-95149434 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055765 Approved Supported Mitochondria Endometrial cancer:7.98e-7 (unfavourable), Liver cancer:7.73e-5 (unfavourable), Thyroid cancer:6.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 37.9 Expressed in all +ANKRD53 FLJ12056, FLJ36160 ENSG00000144031 Ankyrin repeat domain 53 2 70978380-70985499 Predicted intracellular proteins Evidence at protein level HPA049574 Approved Mixed Tissue enhanced testis: 17.5 adipose tissue: 4.3 Cell line enhanced HHSteC: 1.3;HSkMC: 1.2 +TPRKB CGI-121, CGI121 ENSG00000144034 TP53RK binding protein 2 73729104-73737400 Predicted intracellular proteins Evidence at protein level HPA035712 Approved Supported Cytosol Expressed in all Expressed in all testis: 79.9 Expressed in all +NAT8 ATase2, GLA, Hcml1, TSC501 ENSG00000144035 N-acetyltransferase 8 (putative) 2 73640832-73642393 Enzymes, Predicted membrane proteins Evidence at protein level HPA067855, HPA074519 Enhanced Approved Endoplasmic reticulum Tissue enriched Tissue enriched 18 kidney: 891.8 liver: 49.4 Cell line enriched 12 Hep G2: 8.7 +EXOC6B KIAA0919, SEC15B, SEC15L2 ENSG00000144036 Exocyst complex component 6B 2 72175984-72826041 Predicted intracellular proteins Evidence at protein level HPA034546, HPA063991 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Mixed cerebral cortex: 33.6 Mixed +SFXN5 BBG-TCC ENSG00000144040 Sideroflexin 5 2 72942036-73075619 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015473, HPA056866 Approved Approved Nucleoplasm
Mitochondria Pancreatic cancer:2.26e-6 (favourable) Expressed in all Tissue enhanced cerebral cortex: 39.4 epididymis: 18.6 Mixed +TEX261 MGC32043, TEG-261 ENSG00000144043 Testis expressed 261 2 70985938-70994945 Predicted membrane proteins Evidence at transcript level HPA016631 Approved Approved Nucleoplasm
Cytosol Liver cancer:4.23e-4 (unfavourable), Endometrial cancer:6.17e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 93.1 Expressed in all +DQX1 FLJ23757 ENSG00000144045 DEAQ-box RNA dependent ATPase 1 2 74518131-74526336 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039158 Enhanced Approved Plasma membrane
Cytosol Mixed Tissue enhanced duodenum: 14.4;small intestine: 13.5 colon: 5.5 Cell line enhanced HBEC3-KT: 4.2;Hep G2: 11.5;hTCEpi: 4.3 +DUSP11 PIR1 ENSG00000144048 Dual specificity phosphatase 11 2 73762184-73780157 Predicted intracellular proteins Evidence at protein level HPA021052 Supported Nucleus
Nucleoli fibrillar center
Cytokinetic bridge Liver cancer:2.10e-7 (unfavourable) Expressed in all Expressed in all fallopian tube: 62.4 Expressed in all +ST6GAL2 KIAA1877, SIAT2, St6gal2, St6GalII ENSG00000144057 ST6 beta-galactoside alpha-2,6-sialyltransferase 2 2 106801600-106887108 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014459 Uncertain Approved Nucleus
Nucleoli fibrillar center Tissue enriched Tissue enhanced cerebral cortex: 22.1;thyroid gland: 47.9 testis: 9.8 Cell line enhanced A549: 4.8;PC-3: 5.5;RPMI-8226: 6.7;SCLC-21H: 7.2;U-138 MG: 7.4;U-266/70: 7.5 +NPHP1 JBTS4, NPH1, SLSN1 ENSG00000144061 Nephrocystin 1 2 110122311-110205066 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046093, HPA074071 Uncertain Uncertain Vesicles Mixed Tissue enhanced testis: 46.0 fallopian tube: 28.4 Mixed +MALL BENE ENSG00000144063 Mal, T-cell differentiation protein like 2 110083870-110116566 Predicted membrane proteins Evidence at protein level HPA051410 Uncertain Pancreatic cancer:1.23e-4 (unfavourable) Mixed Tissue enhanced esophagus: 222.2;parathyroid gland: 321.0 small intestine: 182.4 Cell line enhanced A-431: 176.6;A549: 174.8;CAPAN-2: 233.6;fHDF/TERT166: 228.9;HaCaT: 183.5 +THNSL2 FLJ10916, SOFAT, TSH2 ENSG00000144115 Threonine synthase like 2 2 88170295-88186636 Predicted intracellular proteins Evidence at protein level HPA035395 Approved Expressed in all Tissue enhanced parathyroid gland: 74.4 thyroid gland: 38.2 Cell line enhanced HHSteC: 19.8;T-47d: 21.4 +RALB ENSG00000144118 RAS like proto-oncogene B 2 120240064-120294713 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB026010, HPA065232 Enhanced Pancreatic cancer:1.67e-4 (unfavourable) Expressed in all Tissue enriched 8 parathyroid gland: 664.6 placenta: 82.8 Expressed in all +C1QL2 C1QTNF10, CTRP10 ENSG00000144119 Complement C1q like 2 2 119156243-119158889 Predicted secreted proteins Evidence at protein level HPA057934 Uncertain Mixed Tissue enriched 17 cerebral cortex: 2.5 lymph node,testis: 0.1 Cell line enhanced SCLC-21H: 2.8 +TMEM177 MGC10993 ENSG00000144120 Transmembrane protein 177 2 119679167-119686507 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036689, HPA053816 Uncertain Approved Nucleus
Nucleoli fibrillar center Expressed in all Mixed fallopian tube: 16.9 Expressed in all +NT5DC4 ENSG00000144130 5'-nucleotidase domain containing 4 2 112721486-112742879 Predicted intracellular proteins Evidence at transcript level HPA046856 Uncertain Tissue enhanced Tissue enriched 7 testis: 3.4 lymph node: 0.5 Cell line enriched 10 K-562: 14.2 +RABL2A ENSG00000144134 RAB, member of RAS oncogene family-like 2A 2 113627229-113643396 Predicted intracellular proteins Evidence at protein level HPA042642, HPA042700, HPA044007 Approved Approved Vesicles
Centrosome Renal cancer:1.20e-4 (unfavourable) Expressed in all Tissue enhanced fallopian tube: 31.5 cerebral cortex: 8.1 Mixed +SLC20A1 Glvr-1, GLVR1, PiT-1 ENSG00000144136 Solute carrier family 20 member 1 2 112645857-112663827 Predicted membrane proteins, Transporters Evidence at protein level CAB019279, HPA035834 Approved Approved Vesicles Renal cancer:3.44e-5 (unfavourable), Head and neck cancer:6.56e-5 (unfavourable) Expressed in all Expressed in all colon: 51.1 Expressed in all +FBLN7 FLJ37440, TM14 ENSG00000144152 Fibulin 7 2 112138385-112188216 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA034992 Approved Plasma membrane
Cell Junctions Mixed Mixed parathyroid gland: 18.7 Cell line enhanced AF22: 24.3;BJ hTERT+: 14.4;SCLC-21H: 18.6;SH-SY5Y: 13.4;U-2197: 23.6 +ZC3H8 Fliz1, ZC3HDC8 ENSG00000144161 Zinc finger CCCH-type containing 8 2 112211525-112255136 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034803, HPA034804 Approved Supported Nucleoplasm
Nuclear bodies Endometrial cancer:1.12e-6 (unfavourable), Renal cancer:1.89e-4 (unfavourable) Expressed in all Expressed in all testis: 16.2 Expressed in all +LIPT1 MGC12290, MGC13378 ENSG00000144182 Lipoyltransferase 1 2 99154955-99163157 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034802 Approved Urothelial cancer:9.60e-8 (favourable), Lung cancer:5.70e-4 (favourable) Expressed in all Expressed in all testis: 24.3 Expressed in all +CNGA3 ACHM2, CCNC1, CCNCa, CNCG3, CNG3 ENSG00000144191 Cyclic nucleotide gated channel alpha 3 2 98346155-98398601 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA049378, CAB079025 Approved Approved Tissue enriched Mixed esophagus: 1.9 Cell line enriched 7 U-87 MG: 6.9 +FAHD2B DKFZp434N062 ENSG00000144199 Fumarylacetoacetate hydrolase domain containing 2B 2 97083583-97094882 Predicted intracellular proteins Evidence at protein level HPA042145, HPA044987 Approved Glioma:2.81e-4 (unfavourable) Mixed Expressed in all epididymis: 48.4 Mixed +LYG1 SALW1939 ENSG00000144214 Lysozyme g1 2 99284238-99304742 Predicted secreted proteins Evidence at transcript level Renal cancer:8.44e-4 (favourable) Tissue enriched Group enriched 5 kidney: 22.0;testis: 4.8 breast: 2.5 Mixed +AFF3 LAF4, MLLT2-like ENSG00000144218 AF4/FMR2 family member 3 2 99545419-100142739 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA044512, HPA053379 Approved Supported Nucleoplasm
Cytosol Renal cancer:5.64e-4 (unfavourable) Tissue enhanced Mixed prostate: 29.7 Cell line enhanced Daudi: 35.6;U-698: 50.7 +UBXN4 KIAA0242, UBXD2, UBXDC1 ENSG00000144224 UBX domain protein 4 2 135741619-135785055 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036325 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all thyroid gland: 105.0 Expressed in all +NXPH2 NPH2 ENSG00000144227 Neurexophilin 2 2 138670772-138780348 Predicted secreted proteins Evidence at transcript level HPA034759 Approved Mixed Group enriched 9 cerebral cortex: 5.7;kidney: 5.0;ovary: 14.0 endometrium: 0.9 Cell line enhanced AF22: 3.8;SCLC-21H: 1.7;SiHa: 4.0;U-2 OS: 6.3;U-251 MG: 1.7 +SPOPL BTBD33 ENSG00000144228 Speckle type BTB/POZ protein like 2 138501801-138573547 Predicted intracellular proteins Evidence at protein level HPA034687 Uncertain Approved Vesicles Renal cancer:3.63e-4 (favourable) Expressed in all Expressed in all breast: 16.2 Mixed +THSD7B KIAA1679 ENSG00000144229 Thrombospondin type 1 domain containing 7B 2 136765545-137677717 Predicted membrane proteins Evidence at transcript level HPA051416, HPA056745 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced epididymis: 5.1 adipose tissue: 2.0 Group enriched 8 Daudi: 7.8;SCLC-21H: 25.8 +GPR17 ENSG00000144230 G protein-coupled receptor 17 2 127645864-127652639 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA029766 Enhanced Supported Approved Vesicles Tissue enriched Mixed spleen: 9.6 Cell line enhanced HeLa: 1.7;REH: 4.0;TIME: 3.5;U-2 OS: 1.8;U-2197: 1.8;U-251 MG: 2.1 +POLR2D RBP4 ENSG00000144231 RNA polymerase II subunit D 2 127843551-127858157 Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA034694, HPA046092 Approved Supported Nucleoplasm
Nuclear speckles Renal cancer:2.79e-4 (unfavourable), Liver cancer:8.91e-4 (unfavourable) Expressed in all Tissue enriched 5 testis: 134.0 tonsil: 24.4 Expressed in all +AMMECR1L MGC4268 ENSG00000144233 AMMECR1 like 2 127861630-127885922 Predicted intracellular proteins Evidence at protein level HPA000590, HPA057234 Uncertain Approved Nucleus
Cytosol Endometrial cancer:6.10e-4 (unfavourable) Expressed in all Expressed in all testis: 26.3 Expressed in all +GALNT13 GalNAc-T13, KIAA1918 ENSG00000144278 Polypeptide N-acetylgalactosaminyltransferase 13 2 153871913-154453849 Enzymes, Predicted intracellular proteins Evidence at protein level HPA060775 Approved Tissue enriched Group enriched 6 adrenal gland: 6.6;cerebral cortex: 32.7 prostate: 3.5 Cell line enhanced SH-SY5Y: 46.7;WM-115: 33.1 +PKP4 p0071 ENSG00000144283 Plakophilin 4 2 158456964-158682879 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037334, HPA066647, HPA070648 Approved Enhanced Plasma membrane
Cell Junctions Renal cancer:3.29e-7 (favourable), Endometrial cancer:5.80e-4 (favourable) Expressed in all Expressed in all kidney: 65.6 Expressed in all +SCN1A FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI ENSG00000144285 Sodium voltage-gated channel alpha subunit 1 2 165989160-166149214 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA078664 Supported Nucleoplasm
Nuclear bodies
Plasma membrane Tissue enriched Group enriched 41 cerebral cortex: 10.3;fallopian tube: 2.9;lung: 2.2 adrenal gland,placenta,testis: 0.1 Cell line enhanced AF22: 1.1;ASC TERT1: 4.4;Hep G2: 1.1 +SLC4A10 NBCn2, NCBE ENSG00000144290 Solute carrier family 4 member 10 2 161424332-161985282 Predicted membrane proteins, Transporters Evidence at protein level HPA034755 Supported Tissue enhanced Tissue enriched 22 cerebral cortex: 57.5 adrenal gland: 2.6 Cell line enriched 10 Karpas-707: 6.1 +SCRN3 FLJ23142 ENSG00000144306 Secernin 3 2 174395730-174429575 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034689, HPA034690 Approved Approved Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 48.4 Mixed +LNPK KIAA1715, LNP, LNP1, Ul ENSG00000144320 Lunapark, ER junction formation factor 2 175923892-176002839 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014205 Approved Supported Nucleoplasm
Endoplasmic reticulum Expressed in all Expressed in all testis: 44.7 Expressed in all +ZNF385B FLJ25270, ZNF533 ENSG00000144331 Zinc finger protein 385B 2 179441982-179861505 Predicted intracellular proteins Evidence at protein level HPA046086 Supported Nucleoli fibrillar center Renal cancer:1.04e-9 (favourable), Breast cancer:4.86e-8 (favourable) Group enriched Tissue enhanced lung: 27.5 prostate: 20.0 Cell line enhanced Daudi: 12.3;HAP1: 32.8;U-698: 60.0 +TMEFF2 CT120.2, HPP1, TENB2, TPEF, TR ENSG00000144339 Transmembrane protein with EGF like and two follistatin like domains 2 2 191949043-192195709 Predicted membrane proteins Evidence at protein level HPA015587 Uncertain Uncertain Microtubules
Cytokinetic bridge Tissue enriched Tissue enhanced cerebral cortex: 41.0;prostate: 64.1 seminal vesicle: 19.6 Group enriched 6 AF22: 38.8;LHCN-M2: 94.7 +CDCA7 FLJ14736, JPO1 ENSG00000144354 Cell division cycle associated 7 2 173354820-173368997 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005565 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:4.20e-4 (unfavourable), Melanoma:5.50e-4 (unfavourable) Expressed in all Mixed lymph node: 44.7 Mixed +DLX1 ENSG00000144355 Distal-less homeobox 1 2 172084740-172089677 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035666, HPA045884 Approved Approved Nucleus
Vesicles
Cell Junctions Tissue enhanced Tissue enhanced adrenal gland: 1.6;cerebral cortex: 5.0 prostate: 0.8 Cell line enhanced AN3-CA: 103.9 +UBR3 DKFZp434P117, FLJ37422, KIAA2024, ZNF650 ENSG00000144357 Ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 169827458-170084131 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035390 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 39.6 Expressed in all +PHOSPHO2 MGC22679 ENSG00000144362 Phosphatase, orphan 2 2 169694454-169701708 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034726, HPA034727 Uncertain Approved Vesicles Liver cancer:3.82e-6 (unfavourable), Renal cancer:9.53e-4 (favourable) Expressed in all Expressed in all testis: 23.0 Expressed in all +GULP1 CED-6, CED6, GULP ENSG00000144366 GULP, engulfment adaptor PTB domain containing 1 2 188291669-188595931 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020587 Enhanced Approved Vesicles Renal cancer:4.25e-6 (favourable), Stomach cancer:6.17e-4 (unfavourable) Mixed Mixed epididymis: 99.9 Cell line enhanced AF22: 114.8;WM-115: 252.9 +FAM171B FLJ34104, KIAA1946 ENSG00000144369 Family with sequence similarity 171 member B 2 186693971-186765965 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010639, HPA013434 Approved Approved Nucleus
Mitochondria Renal cancer:9.51e-7 (unfavourable), Urothelial cancer:5.03e-4 (unfavourable) Tissue enriched Tissue enriched 6 cerebral cortex: 114.5 parathyroid gland: 19.3 Mixed +HSPD1 GroEL, HSP60, SPG13 ENSG00000144381 Heat shock protein family D (Hsp60) member 1 2 197486581-197516737 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001523, CAB002775, HPA050025, CAB072816 Supported Enhanced Mitochondria Endometrial cancer:1.61e-4 (unfavourable), Liver cancer:2.25e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 834.1 Expressed in all +CCDC150 FLJ39660 ENSG00000144395 Coiled-coil domain containing 150 2 196639554-196763490 Predicted intracellular proteins Evidence at protein level HPA043968, HPA048104 Uncertain Approved Nucleoplasm Mixed Group enriched 9 kidney: 2.6;testis: 8.8 liver: 0.6 Cell line enhanced SCLC-21H: 5.2 +METTL21A FAM119A, HCA557b, HSPA-KMT, LOC151194 ENSG00000144401 Methyltransferase like 21A 2 207580631-207625928 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034712 Uncertain Approved Nucleus
Cytosol Liver cancer:1.87e-5 (unfavourable), Renal cancer:5.43e-4 (unfavourable) Expressed in all Expressed in all spleen: 22.3 Expressed in all +UNC80 C2orf21, FLJ33496, KIAA1843, UNC-80 ENSG00000144406 Unc-80 homolog, NALCN activator 2 209771993-209999300 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042472 Enhanced Approved Vesicles Tissue enhanced Tissue enhanced adrenal gland: 5.1;cerebral cortex: 15.8;testis: 5.2 gallbladder: 1.9 Cell line enhanced AF22: 2.4;SCLC-21H: 4.7;SH-SY5Y: 2.4 +PTH2R PTHR2 ENSG00000144407 Parathyroid hormone 2 receptor 2 208359714-208854503 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA010655 Approved Tissue enhanced Mixed bone marrow: 2.9 Group enriched 9 EFO-21: 10.1;HEL: 14.3;HL-60: 3.1;SH-SY5Y: 6.7 +CPO ENSG00000144410 Carboxypeptidase O 2 206939554-206969474 Enzymes, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 14 small intestine: 131.5 epididymis: 9.3 Not detected +NBEAL1 ALS2CR16, ALS2CR17, MGC164581 ENSG00000144426 Neurobeachin like 1 2 203014879-203226378 Predicted intracellular proteins Evidence at protein level HPA049189, HPA049447 Uncertain Approved Nucleoplasm
Cytosol Mixed Mixed thyroid gland: 7.7 Mixed +KANSL1L C2orf67, FLJ23861, FLJ32349, KIAA1267L, MSL1v2 ENSG00000144445 KAT8 regulatory NSL complex subunit 1 like 2 210021423-210171383 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043102, HPA046790 Uncertain Approved Cytosol Expressed in all Tissue enriched 13 parathyroid gland: 585.1 testis: 46.0 Expressed in all +SPAG16 DKFZp666P1710, FLJ22724, PF20, WDR29 ENSG00000144451 Sperm associated antigen 16 2 213284379-214410501 Predicted intracellular proteins Evidence at protein level HPA037542 Uncertain Approved Plasma membrane
Cytosol Renal cancer:3.82e-4 (favourable), Prostate cancer:4.90e-4 (unfavourable) Expressed in all Expressed in all testis: 84.3 Mixed +ABCA12 DKFZP434G232, ICR2B, LI2 ENSG00000144452 ATP binding cassette subfamily A member 12 2 214931542-215138428 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA078239 Approved Nucleoli
Vesicles
Plasma membrane
Cytosol Mixed Group enriched 6 breast: 7.7;skin: 25.2 tonsil: 2.5 Group enriched 6 hTCEpi: 28.4;SK-BR-3: 13.8;T-47d: 9.1 +SUMF1 FGE, UNQ3037 ENSG00000144455 Sulfatase modifying factor 1 3 3700814-4467281 Disease related genes, Predicted secreted proteins Evidence at protein level HPA038025 Uncertain Renal cancer:4.79e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 72.6 Expressed in all +NYAP2 KIAA1486 ENSG00000144460 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 2 225399710-225654018 Predicted intracellular proteins Evidence at protein level HPA045531 Uncertain Approved Nucleoplasm
Intermediate filaments Not detected Tissue enriched 6 cerebral cortex: 1.8 lung: 0.3 Cell line enhanced SiHa: 2.0 +RHBDD1 DKFZp547E052 ENSG00000144468 Rhomboid domain containing 1 2 226835581-226999215 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA013972, HPA057125 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all testis: 32.2 Mixed +ACKR3 CMKOR1, CXCR7, GPR159, RDC1 ENSG00000144476 Atypical chemokine receptor 3 2 236567787-236582358 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA032003, HPA049718 Approved Supported Vesicles
Plasma membrane Renal cancer:1.76e-6 (unfavourable), Stomach cancer:2.01e-4 (unfavourable), Urothelial cancer:2.93e-4 (unfavourable), Cervical cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all placenta: 176.7 Cell line enhanced RT4: 248.8;SiHa: 100.8;U-2197: 297.4 +TRPM8 ENSG00000144481 Transient receptor potential cation channel subfamily M member 8 2 233917398-234019522 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Liver cancer:7.15e-4 (favourable) Tissue enriched Tissue enriched 8 prostate: 127.3 liver: 16.2 Cell line enhanced Karpas-707: 3.9;RPTEC TERT1: 6.2;SK-MEL-30: 6.6;WM-115: 5.0 +HES6 bHLHb41 ENSG00000144485 Hes family bHLH transcription factor 6 2 238238267-238240662 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA061763 Approved Nucleus
Nucleoli
Nuclear bodies
Cytosol Lung cancer:9.18e-5 (favourable), Liver cancer:2.79e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 76.8 fallopian tube: 22.3 Cell line enhanced NB-4: 122.5;SCLC-21H: 144.1;SK-MEL-30: 141.7 +ESPNL FLJ42568 ENSG00000144488 Espin-like 2 238100157-238133287 Predicted intracellular proteins Evidence at protein level HPA055103 Uncertain Mixed Mixed seminal vesicle: 1.2 Cell line enhanced Daudi: 1.8;HHSteC: 2.1;U-87 MG: 2.0 +ANKMY1 FLJ20499, ZMYND13 ENSG00000144504 Ankyrin repeat and MYND domain containing 1 2 240479422-240569209 Predicted intracellular proteins Evidence at protein level HPA026620 Uncertain Approved Nucleus
Nuclear bodies
Cytosol Urothelial cancer:3.20e-4 (favourable) Expressed in all Group enriched 6 fallopian tube: 39.5;testis: 94.2 parathyroid gland: 11.4 Mixed +COPS7B CSN7B ENSG00000144524 COP9 signalosome subunit 7B 2 231781671-231809254 Predicted intracellular proteins Evidence at protein level HPA034675, HPA034676 Uncertain Supported Nucleoplasm Renal cancer:1.50e-6 (unfavourable), Liver cancer:8.37e-6 (unfavourable) Expressed in all Expressed in all testis: 38.1 Expressed in all +DIS3L2 FAM6A, FLJ36974, MGC42174 ENSG00000144535 DIS3 like 3'-5' exoribonuclease 2 2 231961245-232344350 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035796, HPA035797 Approved Liver cancer:3.41e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.4 Expressed in all +CPNE9 KIAA4217 ENSG00000144550 Copine family member 9 3 9703807-9729908 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 5 cerebral cortex: 12.6 testis: 2.3 Cell line enhanced Daudi: 1.6;U-937: 1.6 +FANCD2 FA-D2, FACD, FAD, FANCD ENSG00000144554 Fanconi anemia complementation group D2 3 10026414-10101930 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016117, HPA063742 Approved Supported Nucleus
Nucleoli
Nuclear bodies
Cytosol Ovarian cancer:5.00e-5 (unfavourable) Expressed in all Mixed testis: 21.7 Mixed +TAMM41 C3orf31, DKFZp434E0519, MGC16471 ENSG00000144559 TAM41 mitochondrial translocator assembly and maintenance homolog 3 11790442-11846919 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036834, HPA044861 Uncertain Approved Cytosol Colorectal cancer:1.23e-4 (favourable) Expressed in all Mixed epididymis: 11.8 Expressed in all +VGLL4 KIAA0121 ENSG00000144560 Vestigial like family member 4 3 11556070-11771350 Predicted intracellular proteins Evidence at protein level HPA038225, HPA038614 Approved Approved Nucleus
Nucleoli fibrillar center Renal cancer:1.32e-5 (favourable) Expressed in all Expressed in all ovary: 111.1 Expressed in all +RAB5A RAB5 ENSG00000144566 RAB5A, member RAS oncogene family 3 19947079-19985175 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004567, HPA049354 Approved Expressed in all Expressed in all parathyroid gland: 79.4 Expressed in all +FAM134A C2orf17, MAG-2, MGC3035 ENSG00000144567 Family with sequence similarity 134 member A 2 219176225-219185479 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011170, HPA011844 Approved Approved Cytosol Liver cancer:1.49e-4 (unfavourable), Colorectal cancer:7.95e-4 (unfavourable) Expressed in all Expressed in all testis: 143.4 Expressed in all +CTDSP1 NLIIF, SCP1 ENSG00000144579 CTD small phosphatase 1 2 218398256-218405941 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062654 Supported Nucleoplasm Expressed in all Expressed in all placenta: 106.8 Expressed in all +CNOT9 CAF40, CT129, RCD1, RCD1+, RQCD1 ENSG00000144580 CCR4-NOT transcription complex subunit 9 2 218568580-218597080 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046622 Approved Renal cancer:4.69e-9 (unfavourable), Liver cancer:8.41e-9 (unfavourable) Expressed in all Expressed in all testis: 48.9 Expressed in all +MARCH4 KIAA1399, MARCH-IV, RNF174 ENSG00000144583 Membrane associated ring-CH-type finger 4 2 216257865-216372027 Enzymes, Predicted membrane proteins Evidence at protein level HPA014348 Approved Mixed Tissue enriched 6 cerebral cortex: 9.1 stomach: 1.6 Cell line enhanced BJ: 63.3;fHDF/TERT166: 37.3 +STK11IP KIAA1898, LIP1, LKB1IP, STK11IP1 ENSG00000144589 Serine/threonine kinase 11 interacting protein 2 219597860-219616451 Predicted intracellular proteins Evidence at protein level HPA036837, HPA036838, HPA053192 Approved Enhanced Vesicles Pancreatic cancer:1.63e-4 (favourable) Expressed in all Expressed in all testis: 39.7 Expressed in all +GMPPA ENSG00000144591 GDP-mannose pyrophosphorylase A 2 219498867-219506989 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035512, HPA035513 Approved Approved Nucleoplasm Renal cancer:1.90e-10 (unfavourable), Liver cancer:1.62e-4 (unfavourable), Stomach cancer:5.24e-4 (favourable) Expressed in all Expressed in all epididymis: 84.1 Expressed in all +GRIP2 KIAA1719 ENSG00000144596 Glutamate receptor interacting protein 2 3 14489111-14556075 Predicted intracellular proteins Evidence at transcript level HPA035673 Approved Cytosol Mixed Tissue enhanced skeletal muscle: 12.4 heart muscle: 8.6 Cell line enhanced BJ hTERT+: 2.5;NTERA-2: 2.1;PC-3: 5.7;SCLC-21H: 4.0;U-2 OS: 2.4 +EAF1 ENSG00000144597 ELL associated factor 1 3 15427355-15450635 Predicted intracellular proteins Evidence at protein level HPA059516, HPA060569, HPA069538 Enhanced Supported Nucleoplasm
Nuclear bodies
Vesicles
Cytokinetic bridge Lung cancer:6.87e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 33.7 Expressed in all +CNTN4 BIG-2 ENSG00000144619 Contactin 4 3 2098813-3057956 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.00e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 48.7 testis: 24.3 Group enriched 6 BEWO: 8.1;CACO-2: 7.6;HEK 293: 5.1;SH-SY5Y: 18.0;WM-115: 5.6 +DYNC1LI1 DNCLI1 ENSG00000144635 Dynein cytoplasmic 1 light intermediate chain 1 3 32525971-32570874 Predicted intracellular proteins Evidence at protein level HPA035013 Approved Supported Centrosome
Cytosol Liver cancer:9.19e-9 (unfavourable) Expressed in all Expressed in all testis: 74.3 Expressed in all +RBMS3 ENSG00000144642 RNA binding motif single stranded interacting protein 3 3 28574791-30010391 Predicted intracellular proteins Evidence at protein level HPA034719 Uncertain Approved Vesicles Renal cancer:1.85e-4 (unfavourable) Mixed Mixed thyroid gland: 28.0 Mixed +GADL1 ENSG00000144644 Glutamate decarboxylase like 1 3 30726200-30894765 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039160, HPA040229 Uncertain Approved Plasma membrane
Cytosol Not detected Tissue enhanced skeletal muscle: 9.0 thyroid gland: 2.5 Cell line enhanced HAP1: 5.0 +OSBPL10 ENSG00000144645 Oxysterol binding protein like 10 3 31657890-32077580 Predicted intracellular proteins Evidence at protein level HPA003636 Approved Golgi apparatus
Plasma membrane
Cytosol Renal cancer:1.51e-4 (favourable), Pancreatic cancer:3.14e-4 (unfavourable), Urothelial cancer:4.85e-4 (unfavourable) Mixed Mixed testis: 32.1 Cell line enhanced hTERT-HME1: 61.7;RPTEC TERT1: 64.6 +POMGNT2 AGO61, C3orf39, FLJ14566, GTDC2 ENSG00000144647 Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 3 43079232-43106076 Disease related genes, Predicted secreted proteins Evidence at protein level HPA034870, HPA040989 Uncertain Renal cancer:4.00e-7 (favourable), Liver cancer:1.26e-5 (unfavourable), Colorectal cancer:8.13e-5 (favourable) Expressed in all Expressed in all endometrium: 35.7 Mixed +ACKR2 CCBP2, CCR10, CCR9, CMKBR9, D6 ENSG00000144648 Atypical chemokine receptor 2 3 42804752-42887974 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013819, HPA073493 Enhanced Supported Nucleoplasm
Vesicles
Cytosol Mixed Tissue enhanced placenta: 22.9 adipose tissue: 5.3 Cell line enhanced BEWO: 50.1;HEL: 15.5;SK-BR-3: 21.0 +FAM198A C3orf41, DKFZP434B172 ENSG00000144649 Family with sequence similarity 198 member A 3 42979267-43060211 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA047726 Approved Supported Vesicles Mixed Mixed fallopian tube: 15.7 Cell line enhanced AN3-CA: 3.7;RPMI-8226: 3.0;T-47d: 7.5 +CSRNP1 AXUD1, DKFZp566F164, FAM130B, TAIP-3, URAX1 ENSG00000144655 Cysteine and serine rich nuclear protein 1 3 39141855-39154562 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045207, HPA058463 Enhanced Nucleoplasm
Vesicles Renal cancer:1.07e-4 (favourable), Stomach cancer:6.47e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 123.5 Cell line enhanced SK-BR-3: 48.5 +SLC25A38 FLJ20551 ENSG00000144659 Solute carrier family 25 member 38 3 39383348-39397351 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041027 Approved Renal cancer:1.58e-5 (favourable), Urothelial cancer:7.29e-4 (favourable) Expressed in all Expressed in all thyroid gland: 65.9 Expressed in all +ITGA9 ALPHA-RLC, ITGA4L, RLC ENSG00000144668 Integrin subunit alpha 9 3 37452115-37823514 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA030609 Approved Approved Nucleoplasm
Vesicles
Plasma membrane
Cell Junctions Expressed in all Mixed thyroid gland: 34.7 Cell line enhanced CACO-2: 8.3;HEL: 7.3;SH-SY5Y: 12.3;WM-115: 6.1 +SLC22A14 OCTL2, ORCTL4 ENSG00000144671 Solute carrier family 22 member 14 3 38282294-38318575 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Tissue enriched 20 testis: 13.5 kidney: 0.6 Not detected +GOLGA4 GCP2, GOLG, golgin-240, p230 ENSG00000144674 Golgin A4 3 37243177-37366751 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035102 Supported Supported Golgi apparatus
Vesicles
Cytosol Renal cancer:3.62e-6 (favourable) Expressed in all Expressed in all testis: 81.0 Expressed in all +CTDSPL C3orf8, HYA22, PSR1, RBSP3, SCP3 ENSG00000144677 CTD small phosphatase like 3 37861960-37984469 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048325 Approved Approved Nucleoplasm
Vesicles Renal cancer:6.22e-14 (favourable) Expressed in all Expressed in all skin: 65.7 Mixed +STAC STAC1 ENSG00000144681 SH3 and cysteine rich domain 3 36380344-36548007 Predicted intracellular proteins, Transporters Evidence at protein level HPA035143 Uncertain Uncertain Nucleoplasm
Plasma membrane Mixed Tissue enhanced parathyroid gland: 23.4;prostate: 21.7 lung: 15.8 Cell line enhanced fHDF/TERT166: 34.6;HaCaT: 28.9;SH-SY5Y: 48.5;U-87 MG: 45.7 +IQSEC1 ARF-GEP100, BRAG2, GEP100, KIAA0763 ENSG00000144711 IQ motif and Sec7 domain 1 3 12897220-13073117 Predicted intracellular proteins Evidence at protein level HPA038143, HPA038144 Uncertain Approved Nucleoli
Vesicles Renal cancer:3.58e-6 (favourable), Breast cancer:3.03e-5 (unfavourable), Pancreatic cancer:9.07e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 83.3 Cell line enhanced BEWO: 75.1 +CAND2 KIAA0667, TIP120B, Tp120b ENSG00000144712 Cullin associated and neddylation dissociated 2 (putative) 3 12796472-12871916 Predicted intracellular proteins Evidence at protein level HPA005777 Approved Approved Nuclear bodies
Cytosol Mixed Tissue enhanced skeletal muscle: 42.3;testis: 29.3 heart muscle: 16.3 Cell line enhanced HEK 293: 18.6;REH: 11.8 +RPL32 L32 ENSG00000144713 Ribosomal protein L32 3 12834485-12841588 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047501, HPA051994 Enhanced Approved Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 4513.7 Expressed in all +PTPRG PTPG, RPTPG ENSG00000144724 Protein tyrosine phosphatase, receptor type G 3 61561569-62297613 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA064237 Uncertain Renal cancer:3.10e-6 (favourable) Expressed in all Tissue enhanced parathyroid gland: 73.5 thyroid gland: 22.8 Mixed +IL17RD FLJ35755, IL-17RD, IL17RLM, SEF ENSG00000144730 Interleukin 17 receptor D 3 57089982-57170306 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039577, HPA043550 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:2.92e-9 (favourable) Mixed Mixed parathyroid gland: 26.8 Group enriched 7 AF22: 24.6;AN3-CA: 62.9;NTERA-2: 39.0;SH-SY5Y: 108.1 +SHQ1 FLJ10539, Shq1p ENSG00000144736 SHQ1, H/ACA ribonucleoprotein assembly factor 3 72749277-72861914 Predicted intracellular proteins Evidence at protein level HPA042792 Uncertain Supported Nucleoplasm Colorectal cancer:2.83e-4 (favourable), Endometrial cancer:6.49e-4 (favourable) Expressed in all Expressed in all testis: 18.0 Expressed in all +SLC25A26 ENSG00000144741 Solute carrier family 25 member 26 3 66133610-66388116 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA026887 Enhanced Supported Mitochondria Renal cancer:1.73e-5 (favourable) Expressed in all Expressed in all thyroid gland: 17.5 Expressed in all +UBA3 hUba3, NAE2, UBE1C ENSG00000144744 Ubiquitin like modifier activating enzyme 3 3 69054730-69080408 Predicted intracellular proteins Evidence at protein level HPA034873, HPA034874, HPA065335 Enhanced Approved Nucleoplasm
Plasma membrane
Centrosome
Cytosol Liver cancer:8.57e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 66.8 Expressed in all +ARL6IP5 DERP11, GTRAP3-18, HSPC127, JWA, PRAF3, Yip6b ENSG00000144746 ADP ribosylation factor like GTPase 6 interacting protein 5 3 69084944-69106066 Predicted membrane proteins, Transporters Evidence at protein level HPA015540, CAB019321 Supported Approved Endoplasmic reticulum Expressed in all Expressed in all prostate: 214.1 Expressed in all +TMF1 ARA160, TMF ENSG00000144747 TATA element modulatory factor 1 3 69019827-69052303 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008729 Approved Supported Golgi apparatus Expressed in all Expressed in all thyroid gland: 28.1 Expressed in all +LRIG1 DKFZP586O1624, LIG-1, LIG1 ENSG00000144749 Leucine rich repeats and immunoglobulin like domains 1 3 66378797-66501263 Predicted membrane proteins Evidence at protein level HPA011846 Approved Approved Cytosol Lung cancer:3.01e-5 (favourable), Urothelial cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 59.6 Cell line enhanced Daudi: 28.6;hTEC/SVTERT24-B: 30.3 +LRTM1 HT017 ENSG00000144771 Leucine rich repeats and transmembrane domains 1 3 54918237-54967088 Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced skeletal muscle: 9.3;spleen: 8.9 esophagus: 4.3 Cell line enhanced HEL: 1.0 +RP11-977G19.10 ENSG00000144785 12 56285916-56316059 Predicted secreted proteins Evidence at protein level HPA038466 Uncertain Not detected Mixed cerebral cortex: 7.9 Mixed +LIMD1 ENSG00000144791 LIM domains containing 1 3 45555394-45686338 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064220 Supported Nucleus
Focal adhesion sites Renal cancer:6.73e-5 (favourable) Expressed in all Expressed in all lung: 26.6 Expressed in all +ZNF660 FLJ36870 ENSG00000144792 Zinc finger protein 660 3 44578223-44599694 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029705 Uncertain Uncertain Nucleoli fibrillar center
Cytosol Mixed Mixed ovary: 3.1 Cell line enhanced AF22: 3.3;HEL: 3.1;NTERA-2: 5.2;RH-30: 3.3 +NFKBIZ FLJ34463, INAP, MAIL ENSG00000144802 NFKB inhibitor zeta 3 101827991-101861022 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA010547, HPA075363 Enhanced Supported Nuclear speckles
Cytoplasmic bodies Renal cancer:4.30e-8 (unfavourable) Expressed in all Expressed in all bone marrow: 268.5 Cell line enhanced BJ hTERT+: 58.3 +COL8A1 C3orf7, MGC9568 ENSG00000144810 Collagen type VIII alpha 1 chain 3 99638475-99799226 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA053107 Enhanced Supported Vesicles Renal cancer:9.39e-8 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 87.4 lung: 56.9 Cell line enhanced fHDF/TERT166: 930.0;LHCN-M2: 289.1;TIME: 423.8 +NXPE3 FAM55C, MGC15606 ENSG00000144815 Neurexophilin and PC-esterase domain family member 3 3 101779202-101827392 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA036259 Uncertain Approved Nucleoplasm
Vesicles Renal cancer:7.76e-6 (unfavourable) Mixed Mixed parathyroid gland: 34.5 Expressed in all +ADGRG7 FLJ14454, GPR128 ENSG00000144820 Adhesion G protein-coupled receptor G7 3 100609589-100695479 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Tissue enhanced Group enriched 6 duodenum: 42.8;liver: 12.5;small intestine: 42.9 colon: 5.3 Not detected +MYH15 KIAA1000 ENSG00000144821 Myosin heavy chain 15 3 108380369-108529322 Predicted intracellular proteins Evidence at protein level HPA034871 Uncertain Approved Nucleoplasm
Centrosome
Mitochondria Not detected Tissue enhanced cerebral cortex: 1.9 testis: 0.8 Cell line enhanced Karpas-707: 1.7;PC-3: 4.7;SH-SY5Y: 1.9;U-87 MG: 1.9 +PHLDB2 FLJ21791, LL5b, LL5beta ENSG00000144824 Pleckstrin homology like domain family B member 2 3 111732497-111976517 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035146, HPA035147 Approved Supported Plasma membrane
Cytosol Renal cancer:7.03e-8 (favourable), Head and neck cancer:2.59e-4 (unfavourable) Expressed in all Mixed placenta: 59.0 Mixed +ABHD10 FLJ11342 ENSG00000144827 Abhydrolase domain containing 10 3 111979010-111993363 Enzymes, Predicted secreted proteins Evidence at protein level HPA036991, HPA036992, HPA066081 Supported Approved Mitochondria Renal cancer:4.72e-9 (favourable), Cervical cancer:7.57e-4 (favourable) Expressed in all Expressed in all epididymis: 62.1 Expressed in all +TAGLN3 NP22, NP25 ENSG00000144834 Transgelin 3 3 111998664-112013887 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062620 Enhanced Tissue enhanced Tissue enriched 8 cerebral cortex: 356.0 adrenal gland: 42.3 Group enriched 6 AF22: 98.0;RPTEC TERT1: 30.7;SCLC-21H: 63.4;SH-SY5Y: 96.4 +PLA1A ps-PLA1 ENSG00000144837 Phospholipase A1 member A 3 119597842-119629811 Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA059740 Approved Nuclear speckles Cervical cancer:2.81e-7 (favourable) Group enriched Group enriched 5 epididymis: 164.9;parathyroid gland: 38.9;seminal vesicle: 93.1 liver: 19.6 Cell line enriched 15 SK-MEL-30: 19.7 +RABL3 MGC23920 ENSG00000144840 RAB, member of RAS oncogene family like 3 3 120686681-120742993 Predicted intracellular proteins Evidence at protein level HPA035150, HPA035151 Uncertain Approved Nucleoplasm Renal cancer:2.79e-5 (favourable) Expressed in all Expressed in all thyroid gland: 33.1 Expressed in all +ADPRH ARH1 ENSG00000144843 ADP-ribosylarginine hydrolase 3 119579268-119589945 Enzymes, Predicted intracellular proteins Evidence at protein level CAB001701, HPA036961 Approved Approved Nucleus
Nuclear membrane Breast cancer:2.42e-4 (favourable) Expressed in all Mixed lung: 20.1 Cell line enhanced HDLM-2: 22.2;HMC-1: 16.3;Karpas-707: 18.2;U-266/70: 18.7 +IGSF11 BT-IgSF, CT119, Igsf13, MGC35227, VSIG3 ENSG00000144847 Immunoglobulin superfamily member 11 3 118900557-119146068 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA046377 Uncertain Approved Nucleus
Cell Junctions
Cytosol Group enriched Tissue enhanced cerebral cortex: 31.0;testis: 64.9 ovary: 20.1 Cell line enhanced A549: 7.2;SK-MEL-30: 26.9;U-266/70: 8.9;U-266/84: 10.2 +ATG3 APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96 ENSG00000144848 Autophagy related 3 3 112532509-112562046 Predicted intracellular proteins Evidence at protein level CAB037260, HPA040471 Enhanced Supported Plasma membrane
Cytosol Liver cancer:9.35e-6 (unfavourable), Prostate cancer:1.59e-4 (unfavourable), Cervical cancer:6.82e-4 (favourable) Expressed in all Expressed in all testis: 154.8 Expressed in all +NR1I2 BXR, ONR1, PAR2, PXR, SXR ENSG00000144852 Nuclear receptor subfamily 1 group I member 2 3 119780484-119818485 FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029309, HPA055121, HPA073926 Enhanced Nucleoplasm Group enriched Group enriched 10 colon: 10.3;duodenum: 27.2;gallbladder: 6.4;liver: 20.0;rectum: 10.7;small intestine: 30.0 stomach: 1.7 Group enriched 7 Hep G2: 9.8;RH-30: 3.3 +BOC CDON2 ENSG00000144857 BOC cell adhesion associated, oncogene regulated 3 113211003-113287459 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025806, HPA060778, HPA061787 Uncertain Supported Nucleoplasm
Plasma membrane Urothelial cancer:1.18e-5 (unfavourable), Head and neck cancer:4.89e-4 (favourable) Mixed Mixed fallopian tube: 51.7 Cell line enhanced AN3-CA: 73.4;ASC diff: 77.9;BJ hTERT+: 34.1 +SRPRB APMCF1, SR-beta ENSG00000144867 SRP receptor beta subunit 3 133784033-133825772 Predicted membrane proteins Evidence at protein level HPA011173 Approved Approved Plasma membrane Liver cancer:3.12e-5 (unfavourable) Expressed in all Expressed in all epididymis: 52.0 Expressed in all +TMEM108 CT124, MGC3040 ENSG00000144868 Transmembrane protein 108 3 133038391-133397792 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA063350 Uncertain Approved Nucleoli
Vesicles
Plasma membrane
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 21.9;testis: 25.8 adrenal gland: 15.0 Cell line enhanced HMC-1: 21.3;SCLC-21H: 24.8;SH-SY5Y: 98.2 +AGTR1 AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R ENSG00000144891 Angiotensin II receptor type 1 3 148697784-148743008 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA003596 Enhanced Uncertain Vesicles Group enriched Tissue enhanced placenta: 214.0 liver: 50.9 Cell line enhanced ASC diff: 127.9;BJ hTERT+ SV40 Large T+: 33.9;HBF TERT88: 54.9;HSkMC: 24.7 +MED12L KIAA1635, TNRC11L, TRALP, TRALPUSH ENSG00000144893 Mediator complex subunit 12 like 3 151085697-151437072 Predicted intracellular proteins Evidence at protein level HPA036807 Uncertain Approved Nucleoli Mixed Tissue enhanced cerebral cortex: 26.6 testis: 8.5 Cell line enhanced BEWO: 17.8;HEL: 18.7 +EIF2A EIF-2A ENSG00000144895 Eukaryotic translation initiation factor 2A 3 150546678-150584242 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036256 Approved Approved Mitochondria
Cytosol Pancreatic cancer:6.57e-6 (unfavourable), Liver cancer:2.36e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 139.1 Expressed in all +ALDH1L1 10-fTHF, FTHFD ENSG00000144908 Aldehyde dehydrogenase 1 family member L1 3 126103562-126197994 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036900, HPA050139 Enhanced Supported Supported Cytosol Renal cancer:2.42e-8 (favourable) Tissue enhanced Tissue enhanced kidney: 121.2;liver: 190.4 adipose tissue: 80.9 Cell line enhanced Hep G2: 54.9;Karpas-707: 57.9;RT4: 174.8 +OSBPL11 FLJ13012, FLJ13164, ORP-11, ORP11 ENSG00000144909 Oxysterol binding protein like 11 3 125528858-125595090 Predicted intracellular proteins Evidence at protein level HPA039144 Approved Nucleoplasm
Golgi apparatus Expressed in all Mixed spleen: 22.9 Expressed in all +TRPC1 HTRP-1 ENSG00000144935 Transient receptor potential cation channel subfamily C member 1 3 142724074-142807888 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB009387, HPA021130 Supported Approved Vesicles Renal cancer:2.72e-5 (unfavourable) Mixed Mixed endometrium: 18.6 Mixed +NCEH1 AADACL1, KIAA1363, NCEH ENSG00000144959 Neutral cholesterol ester hydrolase 1 3 172630249-172711218 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026888 Supported Approved Endoplasmic reticulum Pancreatic cancer:8.25e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 35.0 Cell line enhanced CAPAN-2: 250.8 +SPATA16 NYD-SP12 ENSG00000144962 Spermatogenesis associated 16 3 172889358-173141268 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037884 Enhanced Not detected Tissue enriched 606 testis: 105.7 kidney: 0.1 Not detected +FAM86B2 ENSG00000145002 Family with sequence similarity 86 member B2 8 12425614-12436343 Predicted intracellular proteins Evidence at protein level HPA041610, HPA055718 Uncertain Uncertain Vesicles Not detected Tissue enhanced fallopian tube: 4.3 thyroid gland: 2.3 Cell line enhanced hTERT-HME1: 5.2;RPMI-8226: 11.6;SCLC-21H: 5.5 +LPP ENSG00000145012 LIM domain containing preferred translocation partner in lipoma 3 188153284-188890671 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA011133, HPA017342 Enhanced Enhanced Focal adhesion sites
Cytosol Expressed in all Expressed in all smooth muscle: 117.9 Cell line enhanced EFO-21: 109.0;U-698: 138.0 +TMEM44 DKFZp686O18124 ENSG00000145014 Transmembrane protein 44 3 194587673-194633689 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA043718 Uncertain Approved Cytosol Renal cancer:6.55e-13 (unfavourable) Expressed in all Mixed epididymis: 16.7 Mixed +RUBCN KIAA0226, rubicon, rundataxin ENSG00000145016 RUN and cysteine rich domain containing beclin 1 interacting protein 3 197671393-197749727 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050908, HPA054497 Approved Supported Vesicles
Cytosol Liver cancer:9.91e-5 (unfavourable), Prostate cancer:1.62e-4 (unfavourable), Colorectal cancer:6.65e-4 (unfavourable) Expressed in all Expressed in all spleen,testis: 24.3 Expressed in all +AMT GCST, NKH ENSG00000145020 Aminomethyltransferase 3 49416775-49422753 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005566 Supported Supported Nucleoplasm
Mitochondria Renal cancer:3.90e-8 (favourable) Expressed in all Mixed parathyroid gland: 23.2 Group enriched 12 BEWO: 14.2;Hep G2: 30.0;NTERA-2: 7.6;SH-SY5Y: 11.8 +TCTA ENSG00000145022 T-cell leukemia translocation altered 3 49412206-49416475 Disease related genes, Predicted membrane proteins Evidence at protein level HPA007342 Approved Approved Cytosol Renal cancer:5.00e-15 (favourable), Lung cancer:6.76e-4 (favourable) Expressed in all Expressed in all thyroid gland: 76.2 Expressed in all +NICN1 MGC12936 ENSG00000145029 Nicolin 1 3 49422946-49429326 Predicted intracellular proteins Evidence at protein level HPA058014 Supported Nucleoplasm Renal cancer:8.81e-7 (favourable), Pancreatic cancer:1.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 29.5 Mixed +UCN2 SRP, UCN-II, UCNI, URP ENSG00000145040 Urocortin 2 3 48561727-48563773 Predicted secreted proteins Evidence at protein level HPA066841 Uncertain Approved Vesicles Tissue enhanced Tissue enriched 8 skin: 15.5 endometrium: 2.0 Cell line enhanced hTCEpi: 19.9;hTEC/SVTERT24-B: 21.7;SiHa: 20.5;WM-115: 55.5 +DCAF1 KIAA0800, MGC102804, VPRBP ENSG00000145041 DDB1 and CUL4 associated factor 1 3 51395867-51500002 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036142, HPA052445, HPA053203 Approved Enhanced Nucleus
Nucleoli fibrillar center Renal cancer:7.45e-5 (favourable) Expressed in all Expressed in all testis: 96.8 Expressed in all +MANF ARMET, ARP ENSG00000145050 Mesencephalic astrocyte derived neurotrophic factor 3 51385047-51389397 Predicted secreted proteins Evidence at protein level HPA011175 Approved Supported Endoplasmic reticulum Head and neck cancer:9.58e-6 (unfavourable), Liver cancer:7.48e-4 (unfavourable) Expressed in all Expressed in all epididymis: 125.4 Expressed in all +CCDC39 CILD14, DKFZp434A128, FAP59 ENSG00000145075 Coiled-coil domain containing 39 3 180602858-180871005 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035363, HPA035364 Enhanced Mixed Mixed lymph node: 23.7 Mixed +STXBP5L KIAA1006, LLGL4 ENSG00000145087 Syntaxin binding protein 5 like 3 120908072-121424761 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 15.7;ovary: 12.3;thyroid gland: 14.1 seminal vesicle: 4.8 Cell line enhanced AF22: 6.5;MOLT-4: 5.3;SCLC-21H: 10.6;SH-SY5Y: 4.2 +EAF2 BM040, TRAITS, U19 ENSG00000145088 ELL associated factor 2 3 121835183-121886526 Predicted intracellular proteins Evidence at protein level HPA008411 Enhanced Cervical cancer:2.25e-9 (favourable), Endometrial cancer:2.66e-4 (favourable) Expressed in all Tissue enhanced lymph node: 63.7 bone marrow: 47.8 Cell line enhanced Daudi: 52.5;HL-60: 90.7;U-698: 63.7;U-937: 50.3 +ILDR1 DFNB42, MGC50831 ENSG00000145103 Immunoglobulin like domain containing receptor 1 3 121987323-122022204 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018207 Approved Renal cancer:5.79e-9 (favourable) Mixed Tissue enhanced parathyroid gland: 35.1 cervix, uterine: 20.0 Cell line enhanced CAPAN-2: 6.5;HDLM-2: 10.3;MCF7: 5.7;RT4: 7.7;T-47d: 6.4;U-266/70: 5.6 +TM4SF19 ENSG00000145107 Transmembrane 4 L six family member 19 3 196319342-196338503 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Tissue enhanced Tissue enhanced testis: 9.0 esophagus: 3.1 Cell line enhanced hTEC/SVTERT24-B: 18.9;hTERT-HME1: 24.3;PC-3: 34.0;U-138 MG: 18.7;U-87 MG: 19.9 +MUC4 ENSG00000145113 Mucin 4, cell surface associated 3 195746765-195812277 Predicted membrane proteins Evidence at protein level HPA005895, CAB013536 Approved Tissue enhanced Tissue enhanced colon: 1.0 esophagus: 0.4 Not detected +SLIT2 SLIL3, Slit-2 ENSG00000145147 Slit guidance ligand 2 4 20253260-20620561 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB007590, HPA019511, HPA023088 Uncertain Renal cancer:6.51e-4 (favourable) Mixed Mixed lung: 49.5 Cell line enhanced BJ hTERT+: 175.8;BJ hTERT+ SV40 Large T+: 96.6;fHDF/TERT166: 96.4;HBF TERT88: 115.2 +EIF2B5 EIF-2B, EIF2Bepsilon ENSG00000145191 Eukaryotic translation initiation factor 2B subunit epsilon 3 184135038-184145311 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015412, HPA064370, HPA069303 Uncertain Enhanced Cytosol Liver cancer:3.38e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 39.0 Expressed in all +AHSG A2HS, FETUA, HSGA ENSG00000145192 Alpha 2-HS glycoprotein 3 186612923-186621318 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001524, HPA001525, CAB026209 Enhanced Supported Golgi apparatus Tissue enriched Tissue enriched 1903 liver: 2823.4 testis: 1.4 Cell line enriched 64 Hep G2: 1410.0 +ECE2 KIAA0604, MGC2408 ENSG00000145194 Endothelin converting enzyme 2 3 184249650-184293031 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043346, HPA062215 Enhanced Approved Nucleus
Cytosol Endometrial cancer:8.41e-5 (unfavourable), Liver cancer:5.80e-4 (unfavourable) Expressed in all Mixed adrenal gland: 15.4 Expressed in all +VWA5B2 DKFZp761K032, LOC90113 ENSG00000145198 Von Willebrand factor A domain containing 5B2 3 184230429-184242329 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036823, HPA036824, HPA061412 Enhanced Approved Nucleus
Golgi apparatus Mixed Tissue enriched 10 adrenal gland: 53.4 cerebral cortex: 5.4 Cell line enriched 11 SCLC-21H: 37.2 +DGKQ DAGK, DAGK4, DAGK7 ENSG00000145214 Diacylglycerol kinase theta 4 958887-986895 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026797, CAB033835 Uncertain Expressed in all Expressed in all small intestine: 26.0 Mixed +FIP1L1 DKFZp586K0717, FIP1 ENSG00000145216 Factor interacting with PAPOLA and CPSF1 4 53377643-53460861 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037475, HPA058202 Enhanced Enhanced Nucleoplasm Liver cancer:1.51e-4 (unfavourable) Expressed in all Expressed in all testis: 69.8 Expressed in all +SLC26A1 EDM4, SAT-1 ENSG00000145217 Solute carrier family 26 member 1 4 979073-993440 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA041654 Uncertain Approved Microtubules Renal cancer:1.19e-4 (favourable) Mixed Mixed adrenal gland,kidney: 6.0 Mixed +LYAR ZC2HC2, ZLYAR ENSG00000145220 Ly1 antibody reactive 4 4267701-4290169 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035881 Enhanced Supported Nucleus
Nucleoli Renal cancer:4.36e-10 (unfavourable), Liver cancer:3.20e-5 (unfavourable), Ovarian cancer:8.82e-4 (favourable) Expressed in all Tissue enriched 7 testis: 185.7 lymph node: 27.6 Expressed in all +CENPC CENP-C, CENPC1, hcp-4, MIF2 ENSG00000145241 Centromere protein C 4 67468748-67545606 Predicted intracellular proteins Evidence at protein level HPA049740, HPA058252 Enhanced Nuclear bodies Renal cancer:5.63e-4 (favourable), Lung cancer:9.67e-4 (favourable) Expressed in all Mixed ovary: 6.2 Mixed +EPHA5 CEK7, EHK1, Hek7, TYRO4 ENSG00000145242 EPH receptor A5 4 65319563-65670495 Enzymes, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enriched 5 cerebral cortex: 18.0 cervix, uterine: 3.3 Cell line enhanced PC-3: 8.7;TIME: 10.3;U-138 MG: 25.1;U-2197: 14.6;U-251 MG: 17.0 +CORIN ATC2, CRN, Lrp4, PRSC, TMPRSS10 ENSG00000145244 Corin, serine peptidase 4 47593998-47838106 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA070941 Approved Nuclear bodies
Plasma membrane
Actin filaments Mixed Tissue enhanced heart muscle: 38.6 skin: 9.4 Group enriched 6 ASC diff: 7.2;ASC TERT1: 31.6 +ATP10D ATPVD, KIAA1487 ENSG00000145246 ATPase phospholipid transporting 10D (putative) 4 47485288-47593486 Enzymes, Predicted membrane proteins Evidence at protein level HPA050808 Approved Supported Nucleoplasm
Plasma membrane Renal cancer:5.00e-8 (favourable) Expressed in all Mixed parathyroid gland: 22.5 Cell line enhanced HAP1: 43.0 +OCIAD2 MGC45416 ENSG00000145247 OCIA domain containing 2 4 48885019-48906937 Predicted intracellular proteins Evidence at protein level HPA040979, HPA041090 Enhanced Enhanced Mitochondria Renal cancer:2.67e-5 (favourable), Urothelial cancer:2.34e-4 (favourable), Ovarian cancer:6.56e-4 (favourable), Pancreatic cancer:6.89e-4 (unfavourable), Endometrial cancer:7.37e-4 (favourable) Expressed in all Expressed in all kidney: 151.5 Cell line enhanced U-251 MG: 320.9 +SLC10A4 MGC29802 ENSG00000145248 Solute carrier family 10 member 4 4 48483343-48489196 Predicted membrane proteins, Transporters Evidence at protein level HPA028835 Uncertain Supported Tissue enhanced Tissue enhanced adrenal gland: 6.2;cerebral cortex: 4.0 cervix, uterine: 1.5 Cell line enhanced HAP1: 15.2;K-562: 13.9;SH-SY5Y: 41.0 +SLC10A6 SOAT ENSG00000145283 Solute carrier family 10 member 6 4 86823468-86849263 Predicted membrane proteins Evidence at protein level HPA016662 Enhanced Group enriched Tissue enhanced esophagus: 11.0;skin: 17.3 adipose tissue: 6.2 Cell line enhanced BJ: 1.4;BJ hTERT+: 1.0;HaCaT: 1.1 +SCD5 ACOD4, FADS4, FLJ21032, HSCD5, SCD4 ENSG00000145284 Stearoyl-CoA desaturase 5 4 82629539-82798857 Enzymes, Predicted membrane proteins Evidence at protein level HPA042380 Uncertain Renal cancer:2.32e-5 (favourable) Group enriched Tissue enhanced adrenal gland: 200.6;cerebral cortex: 500.3 epididymis: 117.0 Mixed +PLAC8 C15, onzin ENSG00000145287 Placenta specific 8 4 83090048-83137075 Predicted intracellular proteins Evidence at protein level HPA040465, HPA077912 Supported Approved Cytosol Cervical cancer:3.03e-4 (favourable) Mixed Mixed bone marrow: 235.8 Cell line enhanced A-431: 158.5;CAPAN-2: 447.2;HL-60: 259.1;RPMI-8226: 161.8 +ENOPH1 E1, MASA, mtnC ENSG00000145293 Enolase-phosphatase 1 4 82430562-82461091 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004985, HPA044607 Enhanced Approved Nucleoplasm
Nuclear bodies Liver cancer:1.74e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 98.3 Expressed in all +CABS1 C4orf35, CLPH, FLJ32897, NYD-SP26 ENSG00000145309 Calcium binding protein, spermatid associated 1 4 70334966-70337116 Predicted intracellular proteins Evidence at protein level HPA044016, HPA055352 Enhanced Not detected Tissue enriched 601 testis: 151.7 salivary gland: 0.2 Not detected +GC DBP, hDBP, VDBP ENSG00000145321 GC, vitamin D binding protein 4 71741693-71804041 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001526, CAB008596, HPA019855 Supported Renal cancer:5.81e-5 (unfavourable), Liver cancer:8.08e-4 (favourable) Tissue enriched Tissue enriched 5 liver: 3875.6 gallbladder: 712.5 Cell line enhanced HL-60: 1.4;RH-30: 2.5;SiHa: 1.3 +TRMT10A MGC27034, RG9MTD2, TRM10 ENSG00000145331 TRNA methyltransferase 10A 4 99546709-99564032 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047601, HPA058241 Uncertain Approved Nucleoplasm
Nucleoli
Actin filaments
Cytosol Thyroid cancer:2.14e-4 (unfavourable) Expressed in all Expressed in all testis: 21.2 Expressed in all +KLHL8 KIAA1378 ENSG00000145332 Kelch like family member 8 4 87160103-87240314 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013856, HPA017762 Approved Enhanced Nucleoplasm Renal cancer:1.53e-5 (favourable) Expressed in all Expressed in all epididymis: 73.6 Expressed in all +SNCA alpha-synuclein, NACP, PARK1, PARK4, PD1 ENSG00000145335 Synuclein alpha 4 89724099-89838315 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA005459, CAB010877 Enhanced Tissue enriched Group enriched 5 bone marrow: 160.8;cerebral cortex: 459.2 endometrium: 57.1 Cell line enhanced HEL: 198.4;HUVEC TERT2: 218.9;SK-MEL-30: 203.3;TIME: 246.6 +PYURF PreY ENSG00000145337 PIGY upstream reading frame 4 88520985-88523813 Predicted intracellular proteins Evidence at protein level HPA036455 Uncertain Approved Nucleoplasm Expressed in all Expressed in all breast: 113.4 Mixed +TBCK HSPC302, MGC16169 ENSG00000145348 TBC1 domain containing kinase 4 106041599-106321495 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039951, HPA051611 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center Renal cancer:3.20e-4 (favourable) Expressed in all Mixed testis: 16.0 Expressed in all +CAMK2D CAMKD ENSG00000145349 Calcium/calmodulin dependent protein kinase II delta 4 113451032-113761927 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026281, HPA051783, HPA051785, HPA053973 Approved Supported Plasma membrane
Cell Junctions
Cytosol Expressed in all Expressed in all heart muscle: 110.3 Mixed +CISD2 ERIS, Miner1, NAF-1, WFS2, ZCD2 ENSG00000145354 CDGSH iron sulfur domain 2 4 102868978-102889242 Disease related genes, Predicted membrane proteins Evidence at protein level HPA015914 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all thyroid gland: 61.9 Expressed in all +DDIT4L REDD2, Rtp801L ENSG00000145358 DNA damage inducible transcript 4 like 4 100185870-100190782 Predicted intracellular proteins Evidence at protein level HPA050903 Uncertain Nucleoplasm
Plasma membrane
Actin filaments Endometrial cancer:5.77e-4 (favourable) Tissue enhanced Tissue enhanced skeletal muscle: 113.3 cervix, uterine: 33.2 Cell line enhanced ASC TERT1: 13.5;BJ: 25.0;fHDF/TERT166: 12.5;HSkMC: 10.7;RPTEC TERT1: 15.6 +ANK2 LQT4 ENSG00000145362 Ankyrin 2 4 112818109-113383740 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA008007, CAB015178, HPA035970 Enhanced Supported Plasma membrane Renal cancer:2.41e-6 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 184.4 kidney: 125.1 Cell line enhanced RH-30: 60.5;SH-SY5Y: 33.1 +TIFA MGC20791, T2BP, T6BP, TIFAA ENSG00000145365 TRAF interacting protein with forkhead associated domain 4 112274542-112285903 Predicted intracellular proteins Evidence at protein level HPA045889 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 37.6 Expressed in all +SPATA5 AFG2, SPAF ENSG00000145375 Spermatogenesis associated 5 4 122923074-123319450 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036450, HPA036451 Approved Approved Cytosol Expressed in all Mixed testis: 4.2 Mixed +FABP2 I-FABP ENSG00000145384 Fatty acid binding protein 2 4 119317250-119322390 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034607, CAB047325, CAB047326 Enhanced Approved Plasma membrane
Actin filaments
Cytosol Group enriched Group enriched 12 duodenum: 261.4;small intestine: 554.5 rectum: 33.8 Not detected +CCNA2 CCN1, CCNA ENSG00000145386 Cyclin A2 4 121816444-121823933 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB000114, HPA020626 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:0.00e+0 (unfavourable), Pancreatic cancer:4.43e-6 (unfavourable), Liver cancer:9.17e-5 (unfavourable), Lung cancer:4.27e-4 (unfavourable), Endometrial cancer:8.78e-4 (unfavourable) Expressed in all Mixed lymph node: 29.3 Expressed in all +METTL14 KIAA1627 ENSG00000145388 Methyltransferase like 14 4 118685368-118715433 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA038002 Supported Supported Nucleoplasm Renal cancer:1.46e-5 (favourable) Expressed in all Expressed in all testis: 23.5 Expressed in all +USP53 KIAA1350 ENSG00000145390 Ubiquitin specific peptidase 53 4 119212587-119295517 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035844, HPA035845 Uncertain Approved Nucleoplasm
Golgi apparatus Renal cancer:3.58e-8 (favourable), Colorectal cancer:3.15e-6 (favourable), Prostate cancer:7.54e-6 (unfavourable) Expressed in all Mixed fallopian tube: 48.8 Cell line enhanced BJ hTERT+: 265.8;SK-MEL-30: 79.9 +SETD7 KIAA1717, KMT7, SET7, SET7/9, Set9 ENSG00000145391 SET domain containing lysine methyltransferase 7 4 139495941-139606699 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058111 Approved Supported Nucleoli Breast cancer:8.28e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 60.7 Mixed +NAF1 ENSG00000145414 Nuclear assembly factor 1 ribonucleoprotein 4 163110073-163166921 Predicted intracellular proteins Evidence at protein level HPA036241, HPA036242, HPA066090 Approved Enhanced Nucleus
Cytosol Expressed in all Expressed in all testis: 24.4 Expressed in all +MARCH1 FLJ20668, MARCH-I, RNF171 ENSG00000145416 Membrane associated ring-CH-type finger 1 4 163524298-164384050 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014600 Uncertain Supported Mitochondria Mixed Mixed lymph node: 36.0 Mixed +SFRP2 FRP-2, SARP1, SDF-5 ENSG00000145423 Secreted frizzled related protein 2 4 153780592-153789120 Predicted secreted proteins Evidence at protein level HPA002652 Approved Intermediate filaments Renal cancer:8.56e-6 (unfavourable), Urothelial cancer:4.39e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 489.6;urinary bladder: 512.1 esophagus: 234.0 Cell line enhanced AF22: 221.7;ASC diff: 57.2;HSkMC: 100.0;NTERA-2: 312.3 +RPS3A MFTL, S3A ENSG00000145425 Ribosomal protein S3A 4 151099573-151104652 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047100, HPA053454 Approved Enhanced Nucleoli
Endoplasmic reticulum
Cytosol Liver cancer:6.56e-4 (unfavourable) Expressed in all Expressed in all ovary: 5260.9 Expressed in all +RNF175 FLJ34190 ENSG00000145428 Ring finger protein 175 4 153710125-153760235 Predicted membrane proteins Evidence at protein level HPA035837 Uncertain Glioma:4.15e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 13.2 seminal vesicle: 4.1 Cell line enhanced AF22: 6.9;REH: 5.6;SH-SY5Y: 6.3;THP-1: 10.0;U-87 MG: 3.4 +PDGFC fallotein, SCDGF ENSG00000145431 Platelet derived growth factor C 4 156760454-156971394 Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA009134 Approved Supported Plasma membrane
Cytosol Renal cancer:1.35e-5 (favourable), Stomach cancer:3.05e-4 (unfavourable), Urothelial cancer:3.17e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 40.6 endometrium: 16.8 Cell line enhanced fHDF/TERT166: 47.4;U-138 MG: 41.4 +CBR4 FLJ14431, SDR45C1 ENSG00000145439 Carbonyl reductase 4 4 168863770-169010275 Predicted intracellular proteins Evidence at protein level HPA037499 Supported Renal cancer:3.64e-14 (favourable) Expressed in all Expressed in all kidney: 28.7 Expressed in all +GLRA3 ENSG00000145451 Glycine receptor alpha 3 4 174636914-174829314 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Tissue enhanced Group enriched 6 breast: 2.6;cerebral cortex: 9.1 adrenal gland: 1.0 Cell line enhanced Karpas-707: 1.4 +CYP4V2 CYP4AH1 ENSG00000145476 Cytochrome P450 family 4 subfamily V member 2 4 186191520-186213456 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA029122 Approved Approved Nuclear speckles Renal cancer:1.49e-7 (favourable), Liver cancer:1.85e-4 (favourable), Endometrial cancer:5.86e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 65.1 liver: 47.4 Cell line enhanced SK-MEL-30: 19.3 +ROPN1L ASP, FLJ25776, RSPH11 ENSG00000145491 Rhophilin associated tail protein 1 like 5 10441524-10472029 Predicted intracellular proteins Evidence at protein level HPA039193, HPA041830 Enhanced Group enriched Tissue enriched 7 testis: 298.1 fallopian tube: 43.4 Cell line enhanced HMC-1: 2.3;NB-4: 8.4 +NDUFS6 CI-13kA ENSG00000145494 NADH:ubiquinone oxidoreductase subunit S6 5 1801400-1816605 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064221 Supported Expressed in all Expressed in all skeletal muscle: 112.0 Expressed in all +MARCH6 MARCH-VI, RNF176, TEB4 ENSG00000145495 Membrane associated ring-CH-type finger 6 5 10353703-10440388 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040841, HPA063246 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all parathyroid gland: 96.8 Expressed in all +NKD2 Naked2 ENSG00000145506 Naked cuticle homolog 2 5 1008829-1038943 Predicted intracellular proteins Evidence at protein level HPA049463 Uncertain Renal cancer:2.66e-5 (unfavourable), Melanoma:9.97e-4 (unfavourable) Expressed in all Tissue enhanced lung: 5.5;skin: 3.8 spleen: 2.9 Cell line enhanced BEWO: 17.2;NB-4: 11.0;RPMI-8226: 29.0 +CDH18 CDH14, EY-CADHERIN ENSG00000145526 Cadherin 18 5 19472951-20575873 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014416 Uncertain Mixed Tissue enhanced adrenal gland: 5.9;cerebral cortex: 19.0 testis: 3.2 Cell line enhanced EFO-21: 4.1;U-2 OS: 7.1;U-2197: 5.6 +ADAMTS16 ADAMTS16s ENSG00000145536 ADAM metallopeptidase with thrombospondin type 1 motif 16 5 5140330-5320304 Predicted secreted proteins Evidence at protein level Renal cancer:3.29e-5 (favourable) Mixed Tissue enhanced gallbladder: 9.9;ovary: 11.2 adipose tissue: 6.3 Cell line enhanced hTEC/SVTERT24-B: 3.9;U-2197: 5.3 +SRD5A1 ENSG00000145545 Steroid 5 alpha-reductase 1 5 6633343-6674386 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA051402 Approved Endometrial cancer:8.73e-6 (unfavourable) Expressed in all Mixed skin: 16.8 Mixed +MYO10 KIAA0799 ENSG00000145555 Myosin X 5 16661914-16936276 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015224, HPA024223 Enhanced Supported Nucleoli
Plasma membrane
Cytosol Renal cancer:2.75e-4 (favourable), Cervical cancer:4.35e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 68.3 Mixed +FAM105A FLJ11127, NET20 ENSG00000145569 Family with sequence similarity 105 member A 5 14581775-14615007 Enzymes, Predicted membrane proteins Evidence at protein level HPA046638 Uncertain Approved Nucleoli
Cytosol Pancreatic cancer:1.02e-4 (favourable), Testis cancer:7.62e-4 (unfavourable) Expressed in all Mixed bone marrow: 35.5 Cell line enhanced HMC-1: 87.0;U-937: 38.0 +RPL37 L37 ENSG00000145592 Ribosomal protein L37 5 40825262-40835335 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Renal cancer:2.67e-6 (unfavourable), Urothelial cancer:6.34e-4 (favourable) Expressed in all Expressed in all breast: 925.8 Expressed in all +SKP2 FBL1, FBXL1, p45 ENSG00000145604 S-phase kinase associated protein 2 5 36151989-36184319 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB013491, CAB013533, HPA051196, HPA054633 Approved Supported Nucleus
Cytosol Renal cancer:4.77e-15 (unfavourable), Melanoma:3.72e-7 (unfavourable), Ovarian cancer:8.57e-4 (favourable) Expressed in all Tissue enriched 6 placenta: 84.6 lymph node: 13.7 Expressed in all +OSMR OSMRB ENSG00000145623 Oncostatin M receptor 5 38845858-38945596 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017278 Approved Approved Nucleoli Renal cancer:3.96e-6 (unfavourable), Cervical cancer:4.87e-4 (unfavourable) Expressed in all Mixed smooth muscle: 55.1 Mixed +UGT3A1 FLJ34658 ENSG00000145626 UDP glycosyltransferase family 3 member A1 5 35951010-36001028 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA047697, HPA056290 Uncertain Approved Vesicles
Cytosol Group enriched Tissue enhanced kidney: 53.4;liver: 29.2 duodenum: 9.5 Cell line enriched 51 RH-30: 26.5 +PLK2 SNK ENSG00000145632 Polo like kinase 2 5 58453982-58460260 Enzymes, Predicted intracellular proteins Evidence at protein level CAB009624, HPA069329 Approved Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:2.08e-4 (unfavourable) Expressed in all Expressed in all spleen: 96.0 Cell line enhanced T-47d: 343.8 +FAM159B ENSG00000145642 Family with sequence similarity 159 member B 5 64690308-64718090 Predicted membrane proteins Evidence at protein level HPA011778 Enhanced Tissue enriched Group enriched 8 pancreas: 1.0;stomach: 3.4 cerebral cortex,duodenum: 0.2 Group enriched 17 NTERA-2: 3.5;RPTEC TERT1: 5.5;SCLC-21H: 1.5 +GZMA CTLA3, HFSP ENSG00000145649 Granzyme A 5 55102648-55110252 Enzymes, Predicted secreted proteins Evidence at protein level HPA054134 Uncertain Renal cancer:1.26e-6 (unfavourable), Endometrial cancer:6.44e-6 (favourable), Breast cancer:7.27e-4 (favourable) Expressed in all Mixed spleen: 70.9 Cell line enhanced HL-60: 3.2 +PIK3R1 GRB1, p85, p85-ALPHA ENSG00000145675 Phosphoinositide-3-kinase regulatory subunit 1 5 68215720-68301821 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA001216, CAB004268 Approved Approved Cytosol Liver cancer:8.09e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 132.9 Expressed in all +HAPLN1 CRTL1 ENSG00000145681 Hyaluronan and proteoglycan link protein 1 5 83637805-83721613 Predicted secreted proteins Evidence at protein level HPA019105, HPA019482, HPA025238 Enhanced Approved Supported Vesicles Renal cancer:4.81e-9 (unfavourable) Mixed Tissue enriched 8 placenta: 103.4 cerebral cortex: 12.8 Group enriched 35 PC-3: 130.7;TIME: 73.5;U-2 OS: 149.3 +LHFPL2 KIAA0206 ENSG00000145685 Lipoma HMGIC fusion partner-like 2 5 78485215-78770021 Predicted membrane proteins Evidence at protein level HPA042402 Uncertain Approved Vesicles
Actin filaments Renal cancer:3.45e-7 (unfavourable), Liver cancer:2.73e-4 (unfavourable) Expressed in all Mixed gallbladder: 36.4 Mixed +SSBP2 HSPC116 ENSG00000145687 Single stranded DNA binding protein 2 5 81413021-81751797 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB020834, HPA068605 Approved Supported Nucleoplasm Mixed Expressed in all parathyroid gland: 76.2 Cell line enhanced REH: 178.5 +BHMT BHMT1 ENSG00000145692 Betaine--homocysteine S-methyltransferase 5 79111779-79132290 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038285, HPA058310 Enhanced Supported Cytosol Liver cancer:7.32e-4 (favourable) Tissue enhanced Group enriched 225 kidney: 788.8;liver: 563.6 urinary bladder: 3.0 Cell line enhanced Hep G2: 2.4;NTERA-2: 1.4;SCLC-21H: 1.1 +ANKRD31 FLJ40191 ENSG00000145700 Ankyrin repeat domain 31 5 75068275-75236878 Predicted intracellular proteins Evidence at protein level HPA057566 Enhanced Not detected Tissue enriched 12 testis: 9.9 esophagus: 0.8 Not detected +IQGAP2 ENSG00000145703 IQ motif containing GTPase activating protein 2 5 76403249-76708132 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004241, HPA037403, HPA037404 Uncertain Approved Vesicles
Plasma membrane Renal cancer:9.44e-12 (favourable), Liver cancer:5.65e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 126.8 testis: 92.1 Cell line enhanced CACO-2: 61.1;HMC-1: 186.1;RPMI-8226: 56.3 +CRHBP CRF-BP, CRFBP ENSG00000145708 Corticotropin releasing hormone binding protein 5 76952713-76981158 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA046120 Approved Tissue enhanced Tissue enhanced liver: 69.9;spleen: 42.2 kidney: 30.2 Cell line enhanced BJ hTERT+ SV40 Large T+: 3.2;BJ hTERT+ SV40 Large T+ RasG12V: 3.3;HBF TERT88: 6.0;U-698: 4.8;U-87 MG: 3.6;WM-115: 3.2 +RASA1 CM-AVM, GAP, p120, p120GAP, p120RASGAP, RASA ENSG00000145715 RAS p21 protein activator 1 5 87267888-87391931 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB007789, HPA036393, HPA064556 Enhanced Expressed in all Expressed in all placenta: 136.4 Expressed in all +LIX1 C5orf11, Lft ENSG00000145721 Limb and CNS expressed 1 5 97091867-97142872 Predicted intracellular proteins Evidence at transcript level HPA058426 Uncertain Approved Vesicles
Cytokinetic bridge
Cytosol Endometrial cancer:2.48e-4 (unfavourable) Tissue enhanced Tissue enriched 6 cerebral cortex: 32.8 seminal vesicle: 5.7 Cell line enriched 9 RPTEC TERT1: 24.5 +GIN1 FLJ20125, GIN-1, TGIN1, ZH2C2 ENSG00000145723 Gypsy retrotransposon integrase 1 5 103086000-103120151 Predicted intracellular proteins Evidence at protein level HPA037402, HPA061362 Approved Approved Nucleus
Nucleoli Renal cancer:1.63e-4 (favourable) Expressed in all Mixed testis: 8.3 Expressed in all +PPIP5K2 CFAP160, HISPPD1, KIAA0433, VIP2 ENSG00000145725 Diphosphoinositol pentakisphosphate kinase 2 5 103120149-103212799 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037895, HPA038442 Approved Approved Vesicles Thyroid cancer:1.12e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.3 Expressed in all +PAM PAL, PHM ENSG00000145730 Peptidylglycine alpha-amidating monooxygenase 5 102753981-103031105 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB026119, HPA042260 Enhanced Approved Golgi apparatus
Cytosol Endometrial cancer:1.63e-4 (favourable), Liver cancer:6.20e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 947.8 Cell line enhanced fHDF/TERT166: 553.5 +BDP1 HSA238520, KIAA1241, KIAA1689, TAF3B1, TFC5, TFIIIB150, TFIIIB90, TFNR ENSG00000145734 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 5 71455615-71567820 Predicted intracellular proteins Evidence at protein level Expressed in all Mixed thyroid gland: 1.6 Cell line enhanced TIME: 6.5 +GTF2H2 BTF2, BTF2P44, p44, T-BTF2P44, TFIIH ENSG00000145736 General transcription factor IIH subunit 2 5 71032670-71067689 Predicted intracellular proteins Evidence at protein level HPA047001 Supported Nuclear speckles Mixed Mixed smooth muscle: 7.6 Mixed +SLC30A5 FLJ12496, FLJ12756, MGC5499, ZnT-5, ZNT5, ZNTL1, ZTL1 ENSG00000145740 Solute carrier family 30 member 5 5 69093646-69131069 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA035373 Approved Supported Nucleus
Golgi apparatus Expressed in all Expressed in all thyroid gland: 61.7 Expressed in all +BTF3 BTF3a, BTF3b, NACB ENSG00000145741 Basic transcription factor 3 5 73498408-73505635 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013007, HPA056420 Approved Supported Cytosol Expressed in all Expressed in all ovary: 1442.8 Expressed in all +FBXL17 DKFZP434C1715, Fbl17, Fbx13, FBXO13 ENSG00000145743 F-box and leucine rich repeat protein 17 5 107859035-108382098 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036410, HPA036411 Uncertain Approved Nucleus Renal cancer:4.60e-8 (favourable), Thyroid cancer:3.27e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 44.2 Expressed in all +SPATA9 FLJ35906, NYD-SP16 ENSG00000145757 Spermatogenesis associated 9 5 95652181-95698711 Predicted membrane proteins Evidence at protein level HPA010848 Uncertain Approved Mitochondria Not detected Tissue enriched 39 testis: 53.6 adipose tissue: 1.3 Not detected +TSLP ENSG00000145777 Thymic stromal lymphopoietin 5 111070062-111078024 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced gallbladder: 15.0 prostate: 10.4 Cell line enhanced ASC TERT1: 10.5;HHSteC: 14.4;hTEC/SVTERT24-B: 22.1;hTERT-HME1: 9.6;U-87 MG: 13.8 +TNFAIP8 GG2-1, MDC-3.13, SCC-S2 ENSG00000145779 TNF alpha induced protein 8 5 119268692-119399688 Predicted intracellular proteins Evidence at protein level HPA054434, HPA057089 Uncertain Approved Nucleoplasm Breast cancer:2.45e-4 (favourable) Expressed in all Expressed in all lymph node: 134.4 Expressed in all +FEM1C EUROIMAGE686608, EUROIMAGE783647, FEM1A, KIAA1785 ENSG00000145780 Fem-1 homolog C 5 115520908-115544894 Predicted intracellular proteins Evidence at protein level HPA059919, HPA060977 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.55e-4 (unfavourable), Colorectal cancer:1.83e-4 (favourable) Expressed in all Expressed in all bone marrow: 40.2 Expressed in all +COMMD10 PTD002 ENSG00000145781 COMM domain containing 10 5 116084991-116412762 Predicted intracellular proteins Evidence at protein level HPA045441, HPA075641 Approved Uncertain Plasma membrane
Cytosol Stomach cancer:2.99e-4 (unfavourable), Thyroid cancer:6.93e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 46.8 Expressed in all +ATG12 APG12, APG12L ENSG00000145782 Autophagy related 12 5 115828200-115841858 Predicted intracellular proteins Evidence at protein level CAB013272 Uncertain Renal cancer:1.54e-7 (unfavourable), Liver cancer:1.36e-4 (unfavourable), Thyroid cancer:4.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 25.1 Expressed in all +MEGF10 KIAA1780 ENSG00000145794 Multiple EGF like domains 10 5 127290831-127465737 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 7 cerebral cortex: 15.8 adrenal gland: 2.2 Cell line enhanced AF22: 31.3;RH-30: 37.5 +ADAMTS19 ENSG00000145808 ADAM metallopeptidase with thrombospondin type 1 motif 19 5 129460265-129738683 Predicted secreted proteins Evidence at transcript level HPA056171, HPA058438 Uncertain Approved Vesicles
Midbody Tissue enhanced Group enriched 13 cervix, uterine: 16.8;endometrium: 16.9;placenta: 5.4;smooth muscle: 9.2 adrenal gland: 0.9 Group enriched 7 MCF7: 12.3;SH-SY5Y: 37.6 +YIPF5 FinGER5, SMAP-5 ENSG00000145817 Yip1 domain family member 5 5 144158159-144170714 Predicted membrane proteins Evidence at protein level HPA042338, HPA073622 Enhanced Supported Nucleoplasm
Endoplasmic reticulum
Golgi apparatus
Vesicles Head and neck cancer:1.12e-5 (unfavourable), Liver cancer:3.26e-5 (unfavourable), Breast cancer:7.83e-5 (unfavourable) Expressed in all Expressed in all placenta: 43.2 Expressed in all +ARHGAP26 GRAF, KIAA0621, OPHN1L, OPHN1L1 ENSG00000145819 Rho GTPase activating protein 26 5 142770384-143229011 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035106, HPA035107 Enhanced Approved Cytosol Urothelial cancer:2.88e-6 (favourable), Endometrial cancer:5.93e-6 (favourable), Cervical cancer:1.36e-4 (favourable), Breast cancer:2.05e-4 (favourable), Colorectal cancer:6.95e-4 (favourable) Expressed in all Mixed cerebral cortex: 30.8 Cell line enhanced Karpas-707: 61.5 +CXCL14 BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14 ENSG00000145824 C-X-C motif chemokine ligand 14 5 135570679-135579279 Predicted secreted proteins Evidence at protein level CAB029996 Uncertain Cervical cancer:1.71e-4 (favourable), Colorectal cancer:4.52e-4 (favourable) Expressed in all Tissue enhanced skin: 874.5 kidney: 335.8 Group enriched 12 HAP1: 60.3;hTCEpi: 55.4;RPTEC TERT1: 157.5;U-2 OS: 88.6 +LECT2 chm-II, chm2 ENSG00000145826 Leukocyte cell derived chemotaxin 2 5 135922279-135955034 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043883 Enhanced Liver cancer:4.16e-5 (favourable) Tissue enriched Tissue enriched 16 liver: 230.9 testis: 14.6 Mixed +SLC25A48 FLJ44862, HDMCP ENSG00000145832 Solute carrier family 25 member 48 5 135834649-135888637 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014674 Uncertain Approved Intermediate filaments
Actin filaments Mixed Tissue enhanced cerebral cortex: 17.7;kidney: 7.3 skeletal muscle: 2.7 Cell line enhanced HAP1: 2.4;HEK 293: 1.6;SCLC-21H: 2.0;U-2 OS: 2.3 +DDX46 FLJ25329, KIAA0801, Prp5, PRPF5 ENSG00000145833 DEAD-box helicase 46 5 134758771-134855133 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036554, HPA057501 Supported Enhanced Nuclear speckles Colorectal cancer:9.01e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 36.4 Expressed in all +IL9 HP40, IL-9, P40 ENSG00000145839 Interleukin 9 5 135892246-135895827 Cancer-related genes, Predicted secreted proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 1.7 skin: 0.5 Cell line enriched 235 HDLM-2: 41.4 +TIMD4 ENSG00000145850 T-cell immunoglobulin and mucin domain containing 4 5 156919282-156963255 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA015625, CAB026027 Approved Renal cancer:3.37e-4 (favourable) Tissue enriched Group enriched 6 lymph node: 63.6;testis: 163.0 adipose tissue: 17.9 Group enriched 16 U-266/70: 73.7;U-266/84: 19.8 +RNF145 FLJ31951 ENSG00000145860 Ring finger protein 145 5 159157409-159210053 Predicted membrane proteins Evidence at protein level HPA036562 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.64e-6 (unfavourable) Expressed in all Expressed in all lung: 109.0 Expressed in all +C1QTNF2 CTRP2 ENSG00000145861 C1q and tumor necrosis factor related protein 2 5 160347751-160370641 Predicted secreted proteins Evidence at protein level HPA061290 Approved Approved Golgi apparatus
Centrosome Mixed Mixed cervix, uterine: 4.5 Cell line enhanced RH-30: 33.1;U-138 MG: 14.8;U-2 OS: 8.6 +GABRA6 ENSG00000145863 Gamma-aminobutyric acid type A receptor alpha6 subunit 5 161547063-161702593 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level CAB022462 Approved Not detected Tissue enhanced testis: 1.1 cerebral cortex: 0.3 Not detected +GABRB2 ENSG00000145864 Gamma-aminobutyric acid type A receptor beta2 subunit 5 161288429-161549044 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB001964, HPA067632 Enhanced Tissue enriched Tissue enriched 12 cerebral cortex: 62.8 epididymis: 5.2 Cell line enriched 17 SCLC-21H: 27.6 +FBXO38 Fbx38, FLJ13962, MOKA, SP329 ENSG00000145868 F-box protein 38 5 148383935-148442836 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034821, HPA041444 Approved Supported Nucleoplasm
Plasma membrane
Cytokinetic bridge
Cytosol Expressed in all Expressed in all parathyroid gland: 30.8 Expressed in all +SPINK7 ECG2, ECRG2 ENSG00000145879 Serine peptidase inhibitor, Kazal type 7 (putative) 5 148312419-148315922 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036294 Enhanced Group enriched Group enriched 25 esophagus: 416.8;tonsil: 106.3 cervix, uterine: 10.5 Not detected +PCYOX1L MGC3265 ENSG00000145882 Prenylcysteine oxidase 1 like 5 149358007-149369653 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037463, HPA038402 Approved Approved Nucleoplasm
Mitochondria Expressed in all Tissue enhanced parathyroid gland: 21.4 cerebral cortex: 12.5 Mixed +GLRA1 STHE ENSG00000145888 Glycine receptor alpha 1 5 151822513-151924842 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA016502, CAB079042 Uncertain Supported Not detected Not detected adrenal gland: 0.4 Not detected +TNIP1 ABIN-1, KIAA0113, NAF1, VAN ENSG00000145901 TNFAIP3 interacting protein 1 5 151029945-151093577 Predicted intracellular proteins Evidence at protein level HPA037893, HPA037894, HPA071950 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:6.86e-5 (favourable), Breast cancer:5.69e-4 (favourable) Expressed in all Expressed in all adipose tissue: 132.2 Expressed in all +G3BP1 G3BP, HDH-VIII ENSG00000145907 G3BP stress granule assembly factor 1 5 151771045-151812785 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004052, CAB037068 Supported Enhanced Cytosol Renal cancer:3.33e-4 (unfavourable) Expressed in all Expressed in all testis: 91.0 Expressed in all +ZNF300 ENSG00000145908 Zinc finger protein 300 5 150894392-150904983 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028975, HPA051777 Uncertain Supported Nucleoplasm
Nucleoli Renal cancer:3.21e-6 (unfavourable) Expressed in all Mixed ovary: 12.4 Mixed +N4BP3 LZTS4 ENSG00000145911 NEDD4 binding protein 3 5 178113443-178126087 Predicted intracellular proteins Evidence at protein level HPA030972, HPA030973, HPA061387 Approved Supported Nucleoplasm
Centrosome Renal cancer:2.38e-4 (favourable) Mixed Tissue enhanced placenta: 11.8 parathyroid gland: 10.2 Cell line enhanced MCF7: 15.8;RH-30: 19.3;SK-BR-3: 53.2 +NHP2 FLJ20479, NOLA2 ENSG00000145912 NHP2 ribonucleoprotein 5 178149460-178153967 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA044171, HPA050400 Enhanced Supported Nucleoplasm
Cytosol Endometrial cancer:4.97e-4 (unfavourable), Liver cancer:5.24e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 114.9 Expressed in all +RMND5B FLJ22318, GID2, GID2B ENSG00000145916 Required for meiotic nuclear division 5 homolog B 5 178130996-178150565 Predicted intracellular proteins Evidence at protein level HPA047778 Uncertain Approved Nucleoplasm Renal cancer:7.22e-8 (favourable), Pancreatic cancer:7.66e-4 (favourable) Expressed in all Expressed in all testis: 94.7 Expressed in all +BOD1 FAM44B ENSG00000145919 Biorientation of chromosomes in cell division 1 5 173607514-173616660 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036293 Uncertain Liver cancer:2.49e-6 (unfavourable), Head and neck cancer:2.02e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 82.5 Expressed in all +CPLX2 CPX-2, DKFZp547D155 ENSG00000145920 Complexin 2 5 175796310-175884020 Predicted intracellular proteins Evidence at protein level HPA071191 Uncertain Vesicles Mixed Tissue enhanced cerebral cortex: 236.4;epididymis: 145.5 adrenal gland: 44.3 Group enriched 19 A549: 549.3;Hep G2: 253.5;SCLC-21H: 296.3 +TENM2 KIAA1127, ODZ2, Ten-M2 ENSG00000145934 Teneurin transmembrane protein 2 5 167284799-168264157 Predicted membrane proteins Evidence at protein level HPA038018, HPA038420, HPA068691 Uncertain Approved Nucleoli Urothelial cancer:7.52e-4 (unfavourable) Tissue enriched Tissue enhanced cerebral cortex: 9.0;heart muscle: 17.1 prostate: 3.6 Cell line enhanced fHDF/TERT166: 51.2;HBEC3-KT: 30.8;HDLM-2: 40.1;U-138 MG: 73.5;U-2 OS: 67.5;U-251 MG: 41.3 +KCNMB1 hslo-beta ENSG00000145936 Potassium calcium-activated channel subfamily M regulatory beta subunit 1 5 170374671-170389677 Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:4.13e-6 (unfavourable) Mixed Tissue enhanced seminal vesicle: 64.2;smooth muscle: 69.7 endometrium: 42.0 Cell line enhanced REH: 7.4;U-937: 2.6 +FAM50B D6S2654E, X5L ENSG00000145945 Family with sequence similarity 50 member B 6 3849386-3851317 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064111, HPA067817 Approved Enhanced Nucleoplasm
Cytokinetic bridge Renal cancer:4.01e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 16.0 Cell line enhanced HDLM-2: 81.7 +MYLK4 SgK085 ENSG00000145949 Myosin light chain kinase family member 4 6 2663629-2750966 Enzymes, Predicted membrane proteins Evidence at protein level HPA015860 Uncertain Mixed Tissue enhanced skeletal muscle: 9.8 kidney: 3.1 Cell line enriched 7 HEL: 6.4 +FAM217A C6orf146, MGC43581 ENSG00000145975 Family with sequence similarity 217 member A 6 4049434-4087344 Predicted intracellular proteins Evidence at transcript level HPA035455 Uncertain Not detected Tissue enriched 33 testis: 22.8 epididymis: 0.6 Not detected +TBC1D7 dJ257A7.3, FLJ32666 ENSG00000145979 TBC1 domain family member 7 6 13266542-13328583 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034748 Approved Renal cancer:2.03e-7 (unfavourable), Ovarian cancer:4.98e-5 (favourable) Expressed in all Expressed in all epididymis: 24.4 Expressed in all +FARS2 dJ236A3.1, FARS1 ENSG00000145982 Phenylalanyl-tRNA synthetase 2, mitochondrial 6 5261044-5771580 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018148, HPA028836 Approved Approved Plasma membrane Renal cancer:1.24e-6 (favourable), Colorectal cancer:5.14e-4 (favourable) Expressed in all Expressed in all fallopian tube: 24.5 Expressed in all +GFOD1 ADG-90, C6orf114, FLJ20330 ENSG00000145990 Glucose-fructose oxidoreductase domain containing 1 6 13357830-13487662 Predicted intracellular proteins Evidence at protein level HPA029096 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Endometrial cancer:2.29e-5 (unfavourable), Renal cancer:6.72e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 22.3 Cell line enhanced HEL: 28.5;HMC-1: 41.5 +CDKAL1 FLJ20342 ENSG00000145996 CDK5 regulatory subunit associated protein 1 like 1 6 20534457-21232404 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA057474 Uncertain Vesicles Endometrial cancer:1.03e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 16.0 Cell line enriched 6 SCLC-21H: 222.3 +PSD2 DKFZp761B0514, EFA6C ENSG00000146005 Pleckstrin and Sec7 domain containing 2 5 139795821-139844466 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 29 cerebral cortex: 58.5 epididymis: 2.0 Cell line enhanced SH-SY5Y: 1.0 +LRRTM2 KIAA0416 ENSG00000146006 Leucine rich repeat transmembrane neuronal 2 5 138868923-138875368 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 10 cerebral cortex: 29.0 placenta: 3.0 Group enriched 7 HDLM-2: 14.6;SCLC-21H: 5.8 +ZMAT2 FLJ31121, hSNU23, Snu23 ENSG00000146007 Zinc finger matrin-type 2 5 140698680-140706676 Predicted intracellular proteins Evidence at protein level HPA036518 Approved Approved Nucleus
Mitochondria Colorectal cancer:7.96e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 103.3 Expressed in all +GFRA3 GFRa-3 ENSG00000146013 GDNF family receptor alpha 3 5 138252379-138274671 Predicted membrane proteins Evidence at protein level HPA020731 Approved Uncertain Plasma membrane
Cytosol Mixed Mixed seminal vesicle: 8.1 Cell line enriched 21 SH-SY5Y: 33.1 +KLHL3 KIAA1129 ENSG00000146021 Kelch like family member 3 5 137617500-137736090 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051291 Approved Mixed Mixed thyroid gland: 13.7 Cell line enhanced TIME: 10.9;U-266/70: 6.0 +DCDC2 DCDC2A, DFNB66, KIAA1154, NPHP19, RU2 ENSG00000146038 Doublecortin domain containing 2 6 24171756-24358052 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031582, HPA031583, HPA031584 Enhanced Enhanced Microtubules
Mitotic spindle
Microtubule organizing center
Cytosol Mixed Tissue enhanced kidney: 23.2 parathyroid gland: 15.3 Group enriched 8 CACO-2: 59.2;EFO-21: 45.6;Hep G2: 55.9;RPTEC TERT1: 193.3 +SLC17A4 KIAA2138 ENSG00000146039 Solute carrier family 17 member 4 6 25754699-25781191 Predicted membrane proteins, Transporters Evidence at transcript level HPA055564 Approved Group enriched Group enriched 6 colon: 20.4;duodenum: 28.6;gallbladder: 25.4;liver: 22.3;rectum: 28.9;small intestine: 35.0 pancreas: 4.2 Cell line enriched 5 RPTEC TERT1: 1.1 +HIST1H2BA bA317E16.3, H2BFU, STBP, TSH2B ENSG00000146047 Histone cluster 1 H2B family member a 6 25726777-25727292 Predicted intracellular proteins Evidence at protein level CAB011603, HPA042205, HPA043013 Enhanced Tissue enriched Tissue enriched 112 testis: 11.1 all non-specific tissues: 0.0 Not detected +KAAG1 RU2, RU2AS ENSG00000146049 Kidney associated antigen 1 6 24356903-24358284 Predicted intracellular proteins Evidence at transcript level HPA036021 Approved Mixed Not detected thyroid gland: 0.5 Group enriched 6 CACO-2: 4.4;EFO-21: 3.9;HEK 293: 1.0;Hep G2: 3.6 +TRIM7 GNIP, RNF90 ENSG00000146054 Tripartite motif containing 7 5 181193924-181205293 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA039213 Approved Approved Nucleoplasm
Vesicles
Cytosol Mixed Group enriched 5 skeletal muscle: 67.7;skin: 22.1 esophagus: 8.6 Cell line enhanced HDLM-2: 34.1;PC-3: 18.2 +TRIM41 MGC1127, RINCK ENSG00000146063 Tripartite motif containing 41 5 181222499-181235809 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024204 Approved Supported Nucleoli
Nuclear bodies Thyroid cancer:4.22e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 21.7 Expressed in all +HIGD2A MGC2198, RCF1B ENSG00000146066 HIG1 hypoxia inducible domain family member 2A 5 176388747-176389771 Predicted membrane proteins Evidence at protein level HPA042715 Uncertain Supported Mitochondria
Cytosol Liver cancer:9.47e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 170.9 Expressed in all +FAM193B FLJ10404, IRIZIO, KIAA1931 ENSG00000146067 Family with sequence similarity 193 member B 5 177519788-177554541 Predicted intracellular proteins Evidence at protein level HPA035848, HPA058112 Approved Enhanced Nucleus
Nucleoli Renal cancer:3.71e-8 (unfavourable), Urothelial cancer:1.30e-5 (favourable) Expressed in all Expressed in all skin: 60.2 Expressed in all +PLA2G7 LDL-PLA2, PAFAH ENSG00000146070 Phospholipase A2 group VII 6 46704201-46735693 Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA035916 Uncertain Vesicles Expressed in all Mixed spleen: 37.5 Cell line enhanced NTERA-2: 1.7;PC-3: 3.2;RT4: 1.3;U-2 OS: 1.7 +TNFRSF21 CD358, DR6 ENSG00000146072 TNF receptor superfamily member 21 6 47231532-47309905 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA006746, CAB009805 Approved Renal cancer:7.23e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 105.2 Cell line enhanced RT4: 416.8 +RNF44 KIAA1100 ENSG00000146083 Ring finger protein 44 5 176526697-176538025 Predicted intracellular proteins Evidence at protein level HPA038981 Uncertain Approved Nucleoplasm Endometrial cancer:2.57e-7 (unfavourable), Liver cancer:8.45e-4 (unfavourable) Expressed in all Expressed in all spleen: 50.1 Expressed in all +MUT ENSG00000146085 Methylmalonyl-CoA mutase 6 49430360-49463191 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035971, HPA035972 Enhanced Approved Mitochondria
Cytosol Renal cancer:8.71e-13 (favourable) Expressed in all Expressed in all liver: 104.1 Expressed in all +RASGEF1C FLJ35841 ENSG00000146090 RasGEF domain family member 1C 5 180100791-180209153 Predicted intracellular proteins Evidence at transcript level HPA028242 Uncertain Approved Mitochondria Tissue enhanced Group enriched 8 cerebral cortex: 16.4;testis: 6.1 seminal vesicle: 1.3 Cell line enhanced BEWO: 2.2;MCF7: 1.9;SCLC-21H: 9.1;U-2 OS: 2.5 +DOK3 FLJ22570 ENSG00000146094 Docking protein 3 5 177501907-177511274 Predicted intracellular proteins Evidence at protein level HPA077312 Enhanced Renal cancer:3.82e-11 (unfavourable) Expressed in all Tissue enhanced bone marrow: 92.0 spleen: 63.6 Cell line enhanced Daudi: 120.7;HMC-1: 116.5;REH: 193.3;U-698: 118.3 +ABT1 ENSG00000146109 Activator of basal transcription 1 6 26596952-26600744 Predicted intracellular proteins Evidence at protein level HPA077039 Approved Vesicles Ovarian cancer:1.89e-4 (favourable), Urothelial cancer:3.80e-4 (favourable) Expressed in all Expressed in all lymph node: 17.9 Expressed in all +PPP1R18 KIAA1949, phostensin ENSG00000146112 Protein phosphatase 1 regulatory subunit 18 6 30676389-30687895 Predicted intracellular proteins Evidence at protein level HPA044745, HPA051000 Enhanced Approved Nucleoplasm
Plasma membrane Renal cancer:1.11e-16 (unfavourable), Colorectal cancer:4.71e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 53.3 spleen: 35.1 Mixed +DAAM2 KIAA0381 ENSG00000146122 Dishevelled associated activator of morphogenesis 2 6 39792298-39904877 Predicted intracellular proteins Evidence at protein level HPA051300, HPA054630 Approved Supported Nucleoplasm
Vesicles
Cytosol Renal cancer:2.79e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 110.8 Cell line enhanced HSkMC: 39.9;LHCN-M2: 46.3;SK-MEL-30: 54.3;WM-115: 26.5 +PRIM2 PRIM2A ENSG00000146143 Primase (DNA) subunit 2 6 57314805-57646849 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046566 Supported Nucleoplasm Renal cancer:7.34e-6 (unfavourable), Ovarian cancer:3.00e-5 (favourable), Liver cancer:3.44e-5 (unfavourable), Pancreatic cancer:5.25e-4 (unfavourable), Endometrial cancer:6.98e-4 (unfavourable) Expressed in all Tissue enhanced prostate: 51.6 testis: 11.5 Expressed in all +MLIP C6orf142, CIP, MGC18257 ENSG00000146147 Muscular LMNA interacting protein 6 53929982-54266280 Predicted intracellular proteins Evidence at protein level HPA029252, HPA046654 Approved Approved Nucleoplasm Tissue enhanced Tissue enhanced heart muscle: 112.5;liver: 67.0;skeletal muscle: 45.7 skin: 20.6 Group enriched 7 HUVEC TERT2: 16.4;SK-MEL-30: 14.9 +HMGCLL1 bA418P12.1, DKFZP434G1411 ENSG00000146151 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 6 55434369-55579214 Enzymes, Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 14.5;placenta: 9.0 prostate: 5.2 Cell line enriched 11 SCLC-21H: 7.1 +LGSN GLULD1, LGS ENSG00000146166 Lengsin, lens protein with glutamine synthetase domain 6 63275951-63319977 Predicted intracellular proteins Evidence at protein level HPA030957, HPA039983 Enhanced Approved Nucleoplasm
Vesicles Tissue enhanced Tissue enhanced kidney: 2.8;liver: 2.4;placenta: 1.8 testis: 0.7 Cell line enhanced A549: 5.5;BEWO: 3.0;CACO-2: 1.6;HeLa: 1.5 +FGD2 ZFYVE4 ENSG00000146192 FYVE, RhoGEF and PH domain containing 2 6 37005646-37029070 Predicted intracellular proteins Evidence at protein level HPA029145, HPA049692 Approved Mixed Tissue enhanced spleen: 42.4 lymph node: 25.0 Group enriched 6 CAPAN-2: 2.4;Daudi: 8.2;HDLM-2: 10.5;U-698: 6.3 +SCUBE3 CEGF3, FLJ34743 ENSG00000146197 Signal peptide, CUB domain and EGF like domain containing 3 6 35214419-35253079 Predicted secreted proteins Evidence at protein level HPA040606 Uncertain Supported Plasma membrane Thyroid cancer:1.38e-4 (unfavourable) Tissue enhanced Tissue enriched 7 thyroid gland: 49.4 seminal vesicle: 6.8 Cell line enhanced AF22: 27.2;ASC diff: 56.0;ASC TERT1: 76.2;HSkMC: 37.2;hTEC/SVTERT24-B: 32.0;U-138 MG: 30.4;WM-115: 26.3 +ANO7 IPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G ENSG00000146205 Anoctamin 7 2 241188509-241225377 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035730 Uncertain Tissue enriched Tissue enhanced prostate: 100.6;stomach: 26.0 small intestine: 15.4 Cell line enhanced BEWO: 2.1;Hep G2: 1.5 +CRIP3 bA480N24.2, TLP, TLP-A ENSG00000146215 Cysteine rich protein 3 6 43299710-43308797 Predicted intracellular proteins Evidence at protein level HPA036198 Uncertain Approved Nuclear speckles Tissue enhanced Tissue enhanced heart muscle: 15.9;testis: 15.5 seminal vesicle: 11.8 Cell line enhanced HAP1: 2.9;HEK 293: 3.1;HeLa: 2.4;Hep G2: 4.5;NTERA-2: 5.8;RPMI-8226: 3.4 +TTBK1 KIAA1855 ENSG00000146216 Tau tubulin kinase 1 6 43243680-43288259 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031735, HPA031736 Enhanced Supported Nucleoplasm
Cytosol Tissue enhanced Tissue enriched 6 cerebral cortex: 18.9 small intestine: 3.1 Group enriched 13 SCLC-21H: 24.9;SH-SY5Y: 8.7 +TCTE1 D6S46, DRC5, FAP155, MGC33600 ENSG00000146221 T-complex-associated-testis-expressed 1 6 44278743-44297688 Predicted intracellular proteins Evidence at transcript level HPA031739 Uncertain Vesicles Tissue enhanced Group enriched 13 fallopian tube: 23.1;testis: 35.3 lung: 2.2 Cell line enhanced SCLC-21H: 1.0 +RPL7L1 dJ475N16.4 ENSG00000146223 Ribosomal protein L7 like 1 6 42879618-42889925 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046049, HPA050478 Approved Nucleoli
Mitochondria Liver cancer:8.53e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 71.5 Expressed in all +NFKBIE IKBE ENSG00000146232 NFKB inhibitor epsilon 6 44258166-44265788 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002692, HPA005941, CAB010272 Supported Supported Nucleus
Nucleoli fibrillar center
Cytosol Renal cancer:1.37e-6 (unfavourable), Breast cancer:1.72e-5 (favourable), Liver cancer:3.50e-4 (unfavourable), Urothelial cancer:8.07e-4 (favourable) Expressed in all Mixed spleen: 26.1 Expressed in all +CYP39A1 ENSG00000146233 Cytochrome P450 family 39 subfamily A member 1 6 46549580-46652830 Enzymes, Predicted membrane proteins Evidence at protein level Renal cancer:1.86e-4 (favourable) Tissue enhanced Tissue enhanced liver: 56.8 epididymis: 28.9 Cell line enhanced hTCEpi: 11.0;SiHa: 9.9;U-698: 7.7 +TPBG 5T4, 5T4-AG ENSG00000146242 Trophoblast glycoprotein 6 82363206-82370828 Predicted membrane proteins Evidence at protein level HPA010554 Enhanced Approved Nucleoplasm Colorectal cancer:6.68e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 17.4 Cell line enhanced hTEC/SVTERT24-B: 64.9 +IRAK1BP1 AIP70, SIMPL ENSG00000146243 Interleukin 1 receptor associated kinase 1 binding protein 1 6 78867472-78946440 Predicted intracellular proteins Evidence at protein level HPA035742, HPA035743 Uncertain Approved Vesicles Mixed Tissue enriched 8 bone marrow: 59.8 testis,thyroid gland: 7.0 Mixed +PHIP BRWD2, DCAF14, FLJ20705, ndrp, WDR11 ENSG00000146247 Pleckstrin homology domain interacting protein 6 78935867-79078236 Predicted intracellular proteins Evidence at protein level HPA019140, HPA019838 Approved Supported Nucleoplasm Renal cancer:1.71e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.2 Expressed in all +PRSS35 C6orf158, dJ223E3.1, MGC46520 ENSG00000146250 Protease, serine 35 6 83512538-83525704 Enzymes, Predicted secreted proteins Evidence at protein level HPA038787, HPA038788 Uncertain Tissue enhanced Tissue enhanced ovary: 12.9 cerebral cortex: 9.9 Cell line enhanced CACO-2: 71.2;HAP1: 13.2;RPTEC TERT1: 18.6 +MMS22L C6orf167, dJ39B17.2 ENSG00000146263 MMS22 like, DNA repair protein 6 97142161-97283217 Predicted intracellular proteins Evidence at protein level HPA067042 Supported Nucleoplasm Mixed Tissue enhanced testis: 12.4 bone marrow: 4.5 Expressed in all +FAXC C6orf168, dJ273F20, MGC2817 ENSG00000146267 Failed axon connections homolog 6 99271169-99350062 Predicted intracellular proteins Evidence at protein level HPA039106 Uncertain Approved Nucleoplasm Mixed Tissue enhanced cerebral cortex: 23.5 seminal vesicle: 14.9 Cell line enhanced HAP1: 24.5;SCLC-21H: 40.3;SH-SY5Y: 25.2 +GABRR1 ENSG00000146276 Gamma-aminobutyric acid type A receptor rho1 subunit 6 89177501-89231278 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Not detected Tissue enriched 6 testis: 1.8 placenta: 0.3 Cell line enhanced NTERA-2: 1.2 +PNRC1 B4-2, PROL2, PRR2 ENSG00000146278 Proline rich nuclear receptor coactivator 1 6 89080751-89085160 Predicted intracellular proteins Evidence at protein level HPA029839, HPA066513 Approved Approved Nucleus
Nucleoli Renal cancer:6.88e-6 (unfavourable) Expressed in all Expressed in all ovary: 272.4 Expressed in all +PM20D2 ACY1L2, bA63L7.3 ENSG00000146281 Peptidase M20 domain containing 2 6 89146050-89165565 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030325, HPA030326, HPA030327 Approved Enhanced Nucleoplasm Expressed in all Expressed in all prostate: 41.1 Mixed +RARS2 DALRD2, dJ382I10.6, MGC14993, MGC23778, PRO1992, RARSL ENSG00000146282 Arginyl-tRNA synthetase 2, mitochondrial 6 87514378-87590003 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039987, HPA042645 Uncertain Approved Nuclear bodies
Cytosol Expressed in all Expressed in all testis: 56.9 Expressed in all +SCML4 dJ47M23.1 ENSG00000146285 Sex comb on midleg-like 4 (Drosophila) 6 107704104-107824317 Predicted intracellular proteins Evidence at protein level HPA063326, HPA065958 Approved Enhanced Nucleoplasm Mixed Tissue enhanced lymph node: 16.1 spleen: 11.1 Cell line enriched 6 HDLM-2: 60.8 +TBC1D32 bA57L9.1, BROMI, C6orf170, C6orf171, dJ310J6.1, FLJ30899, FLJ34235 ENSG00000146350 TBC1 domain family member 32 6 121079494-121334745 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013413 Uncertain Approved Mitochondria Mixed Mixed testis: 6.1 Cell line enhanced HDLM-2: 20.6 +CLVS2 bA160A10.4, C6orf212, C6orf213, RLBP1L2 ENSG00000146352 Clavesin 2 6 122995971-123072927 Predicted intracellular proteins Evidence at protein level HPA043764 Uncertain Tissue enhanced Group enriched 6 cerebral cortex: 15.4;prostate: 5.0 endometrium: 1.7 Group enriched 8 HEL: 10.9;SCLC-21H: 10.7 +GPR6 ENSG00000146360 G protein-coupled receptor 6 6 109978256-109980718 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 16 cerebral cortex: 1.5 all non-specific tissues: 0.0 Cell line enriched 11 SCLC-21H: 1.1 +RNF217 C6orf172, dJ84N20.1, IBRDC1, MGC26996 ENSG00000146373 Ring finger protein 217 6 124962545-125092633 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029598 Uncertain Renal cancer:4.60e-5 (unfavourable), Urothelial cancer:1.92e-4 (unfavourable) Expressed in all Tissue enriched 8 parathyroid gland: 95.7 testis: 12.5 Mixed +RSPO3 FLJ14440, THSD2 ENSG00000146374 R-spondin 3 6 127118604-127197765 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA029957 Approved Mixed Tissue enhanced endometrium: 103.2;smooth muscle: 102.9 placenta: 73.2 Cell line enhanced A549: 24.0;U-138 MG: 5.6;U-87 MG: 5.4 +ARHGAP18 bA307O14.2, MacGAP ENSG00000146376 Rho GTPase activating protein 18 6 129576132-129710225 Predicted intracellular proteins Evidence at protein level HPA031595 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Pancreatic cancer:2.54e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 48.0 Cell line enhanced HMC-1: 344.1 +TAAR2 GPR58 ENSG00000146378 Trace amine associated receptor 2 (gene/pseudogene) 6 132617022-132624275 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.4 Not detected +TAAR6 TA4, TRAR4 ENSG00000146383 Trace amine associated receptor 6 6 132570322-132571359 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected kidney: 0.1 Not detected +TAAR8 GPR102, TA5, TAR5, TRAR5 ENSG00000146385 Trace amine associated receptor 8 6 132552693-132553721 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ABRACL C6orf115, Costars, HSPC280, PRO2013 ENSG00000146386 ABRA C-terminal like 6 139028682-139043302 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030217 Enhanced Approved Nucleoplasm
Cytosol Urothelial cancer:1.65e-6 (favourable) Expressed in all Mixed epididymis: 147.3 Mixed +TAAR1 TA1, TAR1, TRAR1 ENSG00000146399 Trace amine associated receptor 1 6 132644984-132646003 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA055614 Approved Tissue enhanced Group enriched 17 fallopian tube: 2.2;stomach: 7.8 duodenum,endometrium,prostate,urinary bladder: 0.2 Not detected +SLC18B1 C6orf192, dJ55C23.6 ENSG00000146409 Solute carrier family 18 member B1 6 132769370-132798553 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA029747, HPA049659 Approved Supported Golgi apparatus
Cytosol Head and neck cancer:3.55e-4 (favourable), Liver cancer:7.90e-4 (unfavourable), Renal cancer:9.24e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 37.5 Mixed +MTFR2 DUFD1, FAM54A ENSG00000146410 Mitochondrial fission regulator 2 6 136231024-136250335 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029792, HPA029794 Approved Uncertain Vesicles Lung cancer:8.28e-4 (unfavourable), Endometrial cancer:9.64e-4 (unfavourable) Mixed Tissue enhanced testis: 12.7 bone marrow: 10.2 Mixed +SLC2A12 GLUT12, GLUT8 ENSG00000146411 Solute carrier family 2 member 12 6 133988697-134052636 Predicted membrane proteins, Transporters Evidence at protein level HPA031593, HPA031594 Approved Enhanced Plasma membrane
Cell Junctions Tissue enriched Tissue enhanced prostate: 43.3 endometrium: 16.1 Cell line enhanced CAPAN-2: 8.0;HaCaT: 6.1;U-2 OS: 10.1 +SHPRH bA545I5.2, FLJ90837, KIAA2023 ENSG00000146414 SNF2 histone linker PHD RING helicase 6 145864245-145964423 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034854, HPA034950 Approved Approved Mitochondria Mixed Mixed ovary: 15.1 Expressed in all +AIG1 AIG-1, dJ95L4.1, FLJ10485 ENSG00000146416 Androgen induced 1 6 143060496-143340304 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA060766 Approved Approved Golgi apparatus Head and neck cancer:3.25e-7 (unfavourable), Cervical cancer:3.26e-6 (unfavourable), Endometrial cancer:3.06e-4 (unfavourable) Expressed in all Expressed in all liver: 153.1 Expressed in all +DYNLT1 TCTEL1 ENSG00000146425 Dynein light chain Tctex-type 1 6 158636474-158644739 Predicted intracellular proteins Evidence at protein level HPA046559 Supported Nucleoplasm Liver cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 273.3 Expressed in all +TIAM2 STEF ENSG00000146426 T-cell lymphoma invasion and metastasis 2 6 154832697-155257723 Predicted intracellular proteins Evidence at protein level HPA011134, HPA013903 Approved Supported Nucleoplasm
Nucleoli fibrillar center
Cytosol Mixed Tissue enhanced cerebral cortex: 18.0;testis: 24.4 thyroid gland: 10.2 Cell line enhanced AF22: 62.0;HDLM-2: 27.3;RH-30: 39.8 +TMEM181 GPR178, KIAA1423 ENSG00000146433 Transmembrane protein 181 6 158536436-158635428 Predicted membrane proteins Evidence at protein level HPA040189 Approved Approved Golgi apparatus
Vesicles Ovarian cancer:1.09e-4 (unfavourable), Cervical cancer:7.26e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 41.5 Expressed in all +PNLDC1 dJ195P10.2, FLJ40240 ENSG00000146453 PARN like, ribonuclease domain containing 1 6 159800249-159820704 Enzymes, Predicted membrane proteins Evidence at protein level HPA052026 Uncertain Mixed Tissue enriched 5 testis: 12.2 fallopian tube: 2.4 Not detected +WTAP KIAA0105, MGC3925, Mum2 ENSG00000146457 Wilms tumor 1 associated protein 6 159725585-159756319 Predicted intracellular proteins Evidence at protein level HPA010549, HPA010550 Supported Enhanced Nucleoplasm
Nuclear speckles Liver cancer:6.57e-6 (unfavourable), Renal cancer:3.01e-5 (unfavourable), Ovarian cancer:7.51e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 177.1 Expressed in all +ZMYM4 KIAA0425, MYM, ZNF198L3, ZNF262 ENSG00000146463 Zinc finger MYM-type containing 4 1 35268967-35422058 Predicted intracellular proteins Evidence at protein level HPA051301, HPA054802 Approved Supported Nucleoplasm
Cytosol Liver cancer:9.75e-9 (unfavourable), Renal cancer:8.10e-4 (unfavourable) Expressed in all Expressed in all testis: 63.9 Expressed in all +VIP ENSG00000146469 Vasoactive intestinal peptide 6 152750798-152759765 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017324, CAB018649, HPA072701 Supported Approved Endoplasmic reticulum Group enriched Group enriched 5 appendix: 209.4;colon: 71.4;rectum: 68.3;small intestine: 52.7;smooth muscle: 58.1 duodenum: 16.8 Cell line enhanced SH-SY5Y: 2.8;TIME: 1.6 +ARMT1 C6orf211, FLJ12910 ENSG00000146476 Acidic residue methyltransferase 1 6 151452258-151470101 Predicted intracellular proteins Evidence at protein level HPA003004, HPA005819 Uncertain Approved Nucleus
Nuclear bodies
Cytosol Colorectal cancer:4.14e-4 (favourable), Cervical cancer:7.09e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 42.6 Expressed in all +SLC22A3 EMT, OCT3 ENSG00000146477 Solute carrier family 22 member 3 6 160348268-160452581 Predicted membrane proteins, Transporters Evidence at protein level HPA029750 Approved Approved Nucleoplasm
Vesicles
Cytosol Cervical cancer:7.19e-5 (unfavourable), Urothelial cancer:7.26e-4 (unfavourable) Mixed Mixed seminal vesicle: 70.8 Cell line enhanced A549: 24.2;HeLa: 24.0;Hep G2: 15.5;RPTEC TERT1: 10.1 +VWDE FLJ14712 ENSG00000146530 Von Willebrand factor D and EGF domains 7 12330885-12403941 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026619, HPA036044 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced thyroid gland: 3.9 breast,epididymis,heart muscle: 1.1 Cell line enhanced K-562: 7.1;NTERA-2: 3.7;SCLC-21H: 7.1 +GNA12 gep ENSG00000146535 G protein subunit alpha 12 7 2728112-2844324 Predicted intracellular proteins Evidence at protein level CAB010046 Approved Supported Cytosol Liver cancer:1.20e-6 (unfavourable), Renal cancer:4.71e-5 (unfavourable), Urothelial cancer:2.27e-4 (unfavourable) Expressed in all Expressed in all placenta: 34.5 Expressed in all +C7orf50 MGC11257, YCR016W ENSG00000146540 Chromosome 7 open reading frame 50 7 996986-1138260 Predicted intracellular proteins Evidence at protein level HPA052281 Approved Approved Nucleus
Nucleoli Pancreatic cancer:6.20e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 55.8 Expressed in all +SDK1 FLJ31425 ENSG00000146555 Sidekick cell adhesion molecule 1 7 3301448-4269000 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011392 Approved Approved Cytosol Pancreatic cancer:4.08e-4 (favourable) Mixed Tissue enhanced cervix, uterine: 15.0 spleen: 6.0 Cell line enhanced BEWO: 10.1;RT4: 8.9;U-2 OS: 13.6 +CCZ1B C7orf28B, DKFZP586I1023, H_NH0577018.2, MGC19819 ENSG00000146574 CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated 7 6794134-6826770 Predicted intracellular proteins Evidence at protein level HPA045114, HPA050006 Uncertain Enhanced Vesicles Mixed Expressed in all parathyroid gland: 48.7 Expressed in all +C7orf26 MGC2718 ENSG00000146576 Chromosome 7 open reading frame 26 7 6590017-6608726 Predicted intracellular proteins Evidence at protein level HPA042899, HPA052175 Uncertain Approved Nucleus
Nucleoli
Intermediate filaments
Cytosol Pancreatic cancer:6.95e-5 (favourable) Expressed in all Expressed in all spleen: 25.7 Expressed in all +RBAK ZNF769 ENSG00000146587 RB associated KRAB zinc finger 7 5045821-5069488 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071231 Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 14.8 Expressed in all +CREB5 CRE-BPA, H_GS165L15.1 ENSG00000146592 CAMP responsive element binding protein 5 7 28299321-28825894 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050020, HPA061622 Approved Nucleus
Vesicles
Plasma membrane Mixed Mixed gallbladder: 18.6 Cell line enhanced HL-60: 49.5 +FERD3L bHLHa31, N-TWIST, NATO3 ENSG00000146618 Fer3 like bHLH transcription factor 7 19144782-19145421 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043494 Uncertain Not detected Not detected cerebral cortex: 0.5 Cell line enriched 129 SCLC-21H: 12.8 +EGFR ERBB, ERBB1 ENSG00000146648 Epidermal growth factor receptor 7 55019021-55211628 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB000035, HPA001200, HPA018530, CAB068186, CAB073534 Enhanced Enhanced Plasma membrane Urothelial cancer:2.04e-5 (unfavourable) Expressed in all Tissue enhanced placenta: 100.0 skin: 58.7 Cell line enriched 15 A-431: 4682.9 +CDCA5 ENSG00000146670 Cell division cycle associated 5 11 65066300-65084164 Predicted intracellular proteins Evidence at protein level HPA023691 Approved Supported Nucleoplasm Renal cancer:0.00e+0 (unfavourable), Liver cancer:8.21e-6 (unfavourable), Pancreatic cancer:8.72e-6 (unfavourable), Endometrial cancer:2.67e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 31.0;testis: 46.5 lymph node: 18.9 Mixed +IGFBP3 BP-53, IBP3 ENSG00000146674 Insulin like growth factor binding protein 3 7 45912245-45921874 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010360 Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:5.07e-7 (unfavourable), Colorectal cancer:1.08e-4 (unfavourable), Liver cancer:1.64e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 2671.0 endometrium: 886.0 Cell line enhanced fHDF/TERT166: 6647.1;U-2197: 3223.6;U-87 MG: 1735.3 +PURB PURBETA ENSG00000146676 Purine rich element binding protein B 7 44876293-44885361 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048766 Supported Nucleus Expressed in all Expressed in all cerebral cortex: 24.5 Expressed in all +IGFBP1 AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12 ENSG00000146678 Insulin like growth factor binding protein 1 7 45888357-45893668 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB004445, HPA046972, HPA050640 Enhanced Approved Golgi apparatus Renal cancer:6.90e-11 (unfavourable), Lung cancer:1.03e-4 (unfavourable), Stomach cancer:6.64e-4 (unfavourable) Tissue enriched Group enriched 52 endometrium: 120.4;liver: 563.0;placenta: 265.8 fallopian tube: 6.0 Group enriched 8 Hep G2: 33.4;U-2197: 71.7;U-87 MG: 128.8 +SSC4D S4D-SRCRB, SRCRB-S4D, SRCRB4D ENSG00000146700 Scavenger receptor cysteine rich family member with 4 domains 7 76389334-76409695 Predicted secreted proteins Evidence at transcript level HPA062611 Uncertain Endometrial cancer:2.83e-6 (unfavourable), Renal cancer:4.71e-4 (unfavourable), Glioma:6.31e-4 (unfavourable) Mixed Group enriched 5 kidney: 1.4;parathyroid gland: 4.2;thyroid gland: 2.0 cervix, uterine: 0.5 Group enriched 12 EFO-21: 6.3;Hep G2: 6.5;U-2 OS: 27.2 +MDH2 ENSG00000146701 Malate dehydrogenase 2 7 76048051-76067508 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019714, HPA019716, HPA019848, HPA026720 Enhanced Enhanced Mitochondria Renal cancer:1.49e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 233.2 Expressed in all +POMZP3 POM-ZP3, POM121 ENSG00000146707 POM121 and ZP3 fusion 7 76609986-76627261 Predicted intracellular proteins Evidence at transcript level HPA049817 Uncertain Approved Nucleoplasm
Nuclear membrane Liver cancer:3.78e-4 (unfavourable), Cervical cancer:4.34e-4 (favourable), Ovarian cancer:9.31e-4 (favourable) Expressed in all Mixed testis: 13.7 Expressed in all +GBAS NIPSNAP2 ENSG00000146729 Glioblastoma amplified sequence 7 55951793-56000181 Predicted intracellular proteins Evidence at protein level HPA063084 Enhanced Supported Mitochondria Renal cancer:3.02e-8 (favourable) Expressed in all Expressed in all skeletal muscle: 224.4 Expressed in all +CCT6A CCT6, Cctz, HTR3, TCP20, TCPZ, TTCP20 ENSG00000146731 Chaperonin containing TCP1 subunit 6A 7 56051630-56063989 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042996, HPA045576, HPA049949 Supported Approved Cytosol Liver cancer:9.00e-10 (unfavourable), Renal cancer:2.19e-4 (unfavourable), Breast cancer:4.04e-4 (unfavourable), Head and neck cancer:8.45e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 120.3 Expressed in all +PSPH PSP ENSG00000146733 Phosphoserine phosphatase 7 56011051-56051604 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020376, HPA029515 Approved Approved Cytosol Liver cancer:2.75e-5 (unfavourable), Breast cancer:2.30e-4 (unfavourable), Pancreatic cancer:3.77e-4 (favourable) Expressed in all Expressed in all fallopian tube: 25.3 Expressed in all +TRIM50 FLJ32804, TRIM50A ENSG00000146755 Tripartite motif containing 50 7 73312539-73328082 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019862, HPA047843 Uncertain Approved Cytosol Renal cancer:9.36e-7 (favourable) Group enriched Tissue enhanced stomach: 10.4;testis: 4.6 kidney: 1.7 Cell line enriched 25 Hep G2: 4.6 +ZNF92 HPF12, TF12 ENSG00000146757 Zinc finger protein 92 7 65373799-65401135 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA003173 Approved Nucleus Liver cancer:6.56e-4 (unfavourable) Expressed in all Mixed breast: 13.2 Expressed in all +ATXN7L1 ATXN7L4, KIAA1218, MGC33190 ENSG00000146776 Ataxin 7 like 1 7 105605067-105876604 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021448 Approved Approved Nucleus
Cytosol Expressed in all Mixed testis: 16.4 Mixed +TMEM168 DKFZp564C012, FLJ13576 ENSG00000146802 Transmembrane protein 168 7 112762382-112790592 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA020389 Approved Lung cancer:4.07e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 44.3 Expressed in all +ASB15 FLJ43370 ENSG00000146809 Ankyrin repeat and SOCS box containing 15 7 123567010-123639481 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced heart muscle: 19.2;skeletal muscle: 43.9 kidney: 7.5 Not detected +C7orf43 FLJ10925 ENSG00000146826 Chromosome 7 open reading frame 43 7 100154420-100158715 Predicted intracellular proteins Evidence at protein level HPA019359, HPA029463, HPA029464 Approved Enhanced Vesicles
Plasma membrane
Microtubule organizing center Pancreatic cancer:6.19e-5 (favourable) Expressed in all Expressed in all testis: 33.1 Expressed in all +SLC12A9 CIP1 ENSG00000146828 Solute carrier family 12 member 9 7 100826820-100867009 Predicted membrane proteins, Transporters Evidence at protein level HPA067536 Approved Ovarian cancer:4.00e-4 (unfavourable), Renal cancer:4.92e-4 (unfavourable), Lung cancer:5.97e-4 (favourable) Expressed in all Mixed placenta: 20.2 Expressed in all +GIGYF1 GYF1, PERQ1 ENSG00000146830 GRB10 interacting GYF protein 1 7 100679507-100689448 Predicted intracellular proteins Evidence at protein level HPA020999, HPA023995 Enhanced Approved Vesicles
Microtubules Pancreatic cancer:1.35e-5 (favourable), Liver cancer:2.30e-4 (unfavourable), Head and neck cancer:7.42e-4 (favourable) Expressed in all Expressed in all endometrium: 35.8 Expressed in all +TRIM4 RNF87 ENSG00000146833 Tripartite motif containing 4 7 99876958-99919600 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019356, HPA029461 Approved Supported Plasma membrane
Cytosol Renal cancer:7.36e-6 (favourable) Expressed in all Expressed in all ovary: 50.6 Mixed +MEPCE BCDIN3, FLJ20257, MePCE ENSG00000146834 Methylphosphate capping enzyme 7 100428790-100434126 Predicted intracellular proteins Evidence at protein level CAB026384, HPA051587 Supported Approved Nucleoplasm
Cell Junctions Renal cancer:1.01e-10 (favourable), Endometrial cancer:6.01e-6 (unfavourable) Expressed in all Expressed in all testis: 87.8 Expressed in all +ZAN ENSG00000146839 Zonadhesin (gene/pseudogene) 7 100733626-100797797 Predicted membrane proteins No evidence Tissue enriched Not detected testis: 0.5 Not detected +TMEM209 FLJ14803, NET31 ENSG00000146842 Transmembrane protein 209 7 130164715-130207770 Predicted membrane proteins Evidence at protein level HPA031678 Uncertain Approved Nuclear membrane
Nuclear speckles
Vesicles Expressed in all Expressed in all testis: 27.5 Expressed in all +AGBL3 CCP3, MGC32955 ENSG00000146856 ATP/GTP binding protein like 3 7 134986508-135147963 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020397, HPA024150 Uncertain Uncertain Nuclear speckles
Mitochondria
Cytosol Renal cancer:4.02e-4 (unfavourable) Mixed Mixed epididymis: 9.6 Cell line enhanced HEK 293: 5.1 +STRA8 ENSG00000146857 Stimulated by retinoic acid 8 7 135231979-135258492 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced testis: 1.6 skin: 0.6 Cell line enhanced BEWO: 1.2;THP-1: 1.7 +ZC3HAV1L C7orf39, MGC14289 ENSG00000146858 Zinc finger CCCH-type containing, antiviral 1 like 7 139025706-139036029 Predicted intracellular proteins Evidence at protein level HPA020386, HPA050741 Uncertain Enhanced Cytosol Cervical cancer:7.35e-4 (unfavourable) Mixed Mixed thyroid gland: 14.2 Mixed +TMEM140 FLJ11000 ENSG00000146859 Transmembrane protein 140 7 135148072-135166215 Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all spleen: 38.1 Mixed +TLK2 MGC44450, PKU-ALPHA ENSG00000146872 Tousled like kinase 2 17 62458658-62615481 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:9.40e-4 (unfavourable) Expressed in all Expressed in all testis: 96.2 Expressed in all +EPHA1 EPH, EPHT, EPHT1 ENSG00000146904 EPH receptor A1 7 143390289-143408892 Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB026144 Uncertain Renal cancer:1.14e-6 (favourable) Mixed Tissue enriched 24 parathyroid gland: 877.3 esophagus: 36.2 Cell line enhanced CACO-2: 29.0;HaCaT: 28.6;NTERA-2: 106.2 +NOM1 C7orf3, PPP1R113, SGD1 ENSG00000146909 Nucleolar protein with MIF4G domain 1 7 156949723-156973182 Predicted intracellular proteins Evidence at protein level HPA019866, HPA051624 Approved Enhanced Nucleoli Expressed in all Mixed testis: 7.5 Expressed in all +CNPY1 ENSG00000146910 Canopy FGF signaling regulator 1 7 155474206-155555450 Predicted intracellular proteins Evidence at transcript level HPA047400 Uncertain Tissue enriched Tissue enhanced testis: 1.8 pancreas: 0.7 Cell line enriched 11 AF22: 30.3 +NCAPG2 CAP-G2, FLJ20311, hCAP-G2, LUZP5, MTB ENSG00000146918 Non-SMC condensin II complex subunit G2 7 158631311-158704829 Predicted intracellular proteins Evidence at protein level HPA026631 Approved Supported Nuclear speckles Liver cancer:3.00e-5 (unfavourable), Renal cancer:4.06e-5 (unfavourable), Head and neck cancer:1.91e-4 (favourable), Melanoma:3.21e-4 (unfavourable), Endometrial cancer:7.94e-4 (unfavourable), Pancreatic cancer:8.50e-4 (unfavourable) Expressed in all Mixed testis: 27.7 Expressed in all +ASB10 GLC1F ENSG00000146926 Ankyrin repeat and SOCS box containing 10 7 151175698-151187832 Disease related genes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 8 skeletal muscle: 27.9 heart muscle: 3.3 Not detected +NLGN4X HLNX, KIAA1260, NLGN, NLGN4 ENSG00000146938 Neuroligin 4, X-linked X 5840637-6228863 Disease related genes, Predicted membrane proteins Evidence at protein level HPA001651 Approved Tissue enhanced Tissue enhanced cerebral cortex: 20.1 ovary: 12.9 Group enriched 5 AF22: 51.1;NTERA-2: 42.7 +SHROOM2 APXL ENSG00000146950 Shroom family member 2 X 9786456-9949443 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051646, HPA061435 Approved Approved Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.35e-7 (favourable) Expressed in all Mixed cerebral cortex: 11.8 Cell line enhanced WM-115: 22.8 +RAB19 RAB19B ENSG00000146955 RAB19, member RAS oncogene family 7 140404043-140426250 Predicted intracellular proteins Evidence at protein level HPA051077 Uncertain Renal cancer:2.36e-8 (favourable) Mixed Mixed parathyroid gland: 6.2 Cell line enhanced CAPAN-2: 4.4;HDLM-2: 10.4;MCF7: 3.8;RT4: 5.6;SK-BR-3: 4.1;T-47d: 5.7 +LUC7L2 CGI-59, CGI-74, FLJ10657, H_NH0792N18.3, hLuc7B2, LUC7B2 ENSG00000146963 LUC7 like 2, pre-mRNA splicing factor 7 139340359-139423457 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051631 Approved Approved Nucleus Renal cancer:4.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 100.7 Expressed in all +DENND2A FAM31D, KIAA1277 ENSG00000146966 DENN domain containing 2A 7 140518420-140673993 Predicted intracellular proteins Evidence at protein level Renal cancer:3.05e-6 (unfavourable), Glioma:4.97e-4 (unfavourable), Colorectal cancer:9.35e-4 (favourable) Tissue enriched Mixed endometrium: 31.6 Cell line enhanced AF22: 53.5;BJ hTERT+: 42.3;RPTEC TERT1: 51.1;U-2197: 29.5 +TMEM27 NX17 ENSG00000147003 Transmembrane protein 27 X 15627318-15665031 Predicted membrane proteins, Transporters Evidence at protein level HPA048543 Enhanced Approved Endoplasmic reticulum
Vesicles Renal cancer:6.78e-9 (favourable), Ovarian cancer:5.65e-4 (favourable) Tissue enriched Tissue enriched 16 kidney: 422.0 parathyroid gland: 26.6 Cell line enhanced HaCaT: 6.8;RPTEC TERT1: 5.3 +SH3KBP1 CIN85 ENSG00000147010 SH3 domain containing kinase binding protein 1 X 19533975-19887601 Predicted intracellular proteins Evidence at protein level HPA003351, HPA003355, CAB021892 Enhanced Supported Cytosol Renal cancer:2.10e-6 (unfavourable) Expressed in all Expressed in all lymph node: 79.5 Expressed in all +TMEM47 BCMP1, DKFZp564E153, DKFZP761J17121, TM4SF10, VAB-9 ENSG00000147027 Transmembrane protein 47 X 34627064-34657288 Predicted membrane proteins Evidence at protein level HPA046658 Approved Approved Nuclear membrane Renal cancer:4.05e-6 (favourable), Melanoma:2.10e-4 (unfavourable) Expressed in all Mixed endometrium: 75.5 Cell line enhanced BJ: 94.7;fHDF/TERT166: 268.6 +LANCL3 FLJ42925 ENSG00000147036 LanC like 3 X 37571569-37684463 Predicted intracellular proteins Evidence at protein level HPA005470, HPA076575 Approved Approved Mitochondria Not detected Mixed esophagus: 1.3 Cell line enhanced HEL: 12.8;HMC-1: 3.9;K-562: 3.0 +SYTL5 ENSG00000147041 Synaptotagmin like 5 X 38006582-38128819 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026074 Uncertain Approved Nucleoplasm
Microtubules
Cytosol Mixed Tissue enhanced stomach: 11.8 placenta: 10.6 Cell line enhanced CACO-2: 5.1;MCF7: 4.4;SK-MEL-30: 11.6;U-2 OS: 5.0 +CASK CAGH39, FGS4, LIN2, TNRC8 ENSG00000147044 Calcium/calmodulin dependent serine protein kinase X 41514934-41923463 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB001949, HPA023857 Enhanced Approved Nucleoplasm
Cytosol Pancreatic cancer:6.11e-5 (unfavourable) Expressed in all Expressed in all small intestine: 34.5 Mixed +KDM6A UTX ENSG00000147050 Lysine demethylase 6A X 44873177-45112602 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000568, HPA001165, HPA002111 Enhanced Approved Nucleoli Expressed in all Expressed in all bone marrow: 41.0 Mixed +SPIN2A DXF34, SPIN2, TDRD25 ENSG00000147059 Spindlin family member 2A X 57134530-57137625 Predicted intracellular proteins Evidence at protein level HPA000162, HPA069835 Uncertain Approved Nucleoplasm Not detected Mixed cerebral cortex: 1.6 Mixed +MSN ENSG00000147065 Moesin X 65588377-65741931 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047338 Enhanced Enhanced Plasma membrane Renal cancer:1.60e-5 (unfavourable) Expressed in all Expressed in all lung: 420.9 Mixed +AKAP4 AKAP82, CT99, Fsc1, hAKAP82, HI, p82 ENSG00000147081 A-kinase anchoring protein 4 X 50190768-50201013 Predicted intracellular proteins Evidence at protein level HPA005949, HPA020046 Enhanced Not detected Tissue enriched 2796 testis: 279.5 all non-specific tissues: 0.0 Not detected +CCNB3 ENSG00000147082 Cyclin B3 X 50202713-50351910 Predicted intracellular proteins Evidence at protein level HPA000496 Enhanced Supported Nuclear speckles Not detected Group enriched 9 epididymis: 5.8;testis: 7.9 cerebral cortex: 0.7 Cell line enhanced CAPAN-2: 1.5 +HDAC8 HDACL1, MRXS6, RPD3, WTS ENSG00000147099 Histone deacetylase 8 X 72329516-72573103 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA048560 Supported Supported Nucleus
Plasma membrane Expressed in all Expressed in all epididymis: 27.1 Expressed in all +SLC16A2 AHDS, DXS128, MCT7, MCT8, MRX22, XPCT ENSG00000147100 Solute carrier family 16 member 2 X 74421461-74533917 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA072719 Approved Plasma membrane Breast cancer:8.88e-5 (unfavourable), Renal cancer:1.83e-4 (unfavourable), Urothelial cancer:3.16e-4 (unfavourable) Expressed in all Mixed adrenal gland: 24.0 Cell line enhanced BJ: 73.2 +CXorf36 DIA1R, FLJ14103 ENSG00000147113 Chromosome X open reading frame 36 X 45148374-45200901 Disease related genes, Predicted secreted proteins Evidence at transcript level HPA002806 Uncertain Expressed in all Tissue enhanced placenta: 58.4 adipose tissue: 36.3 Cell line enriched 145 HUVEC TERT2: 67.8 +ZNF157 HZF22 ENSG00000147117 Zinc finger protein 157 X 47370583-47414305 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA003319 Uncertain Tissue enhanced Mixed fallopian tube: 2.1 Cell line enhanced U-266/84: 1.6 +ZNF182 HHZ150, KOX14, Zfp182, ZNF21 ENSG00000147118 Zinc finger protein 182 X 47974851-48003978 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA059574 Uncertain Approved Nucleus Urothelial cancer:1.55e-7 (favourable), Renal cancer:2.42e-5 (unfavourable), Liver cancer:3.73e-4 (unfavourable) Expressed in all Mixed thyroid gland: 9.2 Expressed in all +CHST7 C6ST-2, C6ST2 ENSG00000147119 Carbohydrate sulfotransferase 7 X 46573784-46598408 Enzymes, Predicted secreted proteins Evidence at protein level HPA003919 Approved Cervical cancer:7.20e-4 (favourable) Expressed in all Mixed spleen: 12.8 Cell line enhanced EFO-21: 22.4;NTERA-2: 21.4 +KRBOX4 FLJ20344, ZNF673 ENSG00000147121 KRAB box domain containing 4 X 46446857-46497422 Predicted intracellular proteins Evidence at protein level HPA065295 Approved Nucleoplasm Renal cancer:1.98e-7 (unfavourable), Liver cancer:2.87e-6 (unfavourable), Lung cancer:4.67e-5 (favourable), Urothelial cancer:2.17e-4 (favourable) Expressed in all Expressed in all endometrium: 29.3 Mixed +NDUFB11 ESSS, Np15, NP17.3 ENSG00000147123 NADH:ubiquinone oxidoreductase subunit B11 X 47142216-47145504 Disease related genes, Predicted membrane proteins Evidence at protein level HPA030367 Supported Enhanced Mitochondria Expressed in all Expressed in all skeletal muscle: 129.1 Expressed in all +ZNF41 MGC8941, MRX89 ENSG00000147124 Zinc finger protein 41 X 47445879-47482946 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA069102 Enhanced Approved Nucleoplasm Renal cancer:6.95e-4 (favourable), Head and neck cancer:8.32e-4 (favourable) Expressed in all Mixed parathyroid gland: 19.4 Expressed in all +RAB41 ENSG00000147127 RAB41, member RAS oncogene family X 70282093-70285002 Predicted intracellular proteins Evidence at protein level HPA001510 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 5.0;testis: 7.0 skin: 1.6 Cell line enhanced U-2197: 3.5;U-87 MG: 4.5 +ZMYM3 DXS6673E, KIAA0385, MYM, ZNF198L2, ZNF261 ENSG00000147130 Zinc finger MYM-type containing 3 X 71239624-71255146 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003211, HPA075255 Approved Enhanced Nucleoplasm Liver cancer:5.18e-4 (unfavourable) Expressed in all Expressed in all ovary: 44.0 Expressed in all +TAF1 BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250 ENSG00000147133 TATA-box binding protein associated factor 1 X 71366239-71532374 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001075, CAB016283 Supported Enhanced Nucleoplasm Renal cancer:6.03e-4 (unfavourable), Lung cancer:6.54e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.2 Expressed in all +GPR174 FKSG79 ENSG00000147138 G protein-coupled receptor 174 X 79170972-79172229 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA041025 Enhanced Uncertain Vesicles Mixed Tissue enhanced lymph node: 29.8;spleen: 16.7;tonsil: 17.2 appendix: 12.6 Cell line enriched 8 MOLT-4: 85.1 +NONO NMT55, NRB54, P54, P54NRB, PPP1R114 ENSG00000147140 Non-POU domain containing, octamer-binding X 71283192-71301168 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB022069, HPA054094, HPA054559 Enhanced Enhanced Nucleoplasm Endometrial cancer:9.29e-4 (unfavourable) Expressed in all Expressed in all ovary: 245.9 Expressed in all +CCDC120 JM11 ENSG00000147144 Coiled-coil domain containing 120 X 49053572-49069857 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA000561 Uncertain Mitochondria Expressed in all Mixed skin: 17.9 Cell line enhanced BEWO: 28.0 +LPAR4 GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9 ENSG00000147145 Lysophosphatidic acid receptor 4 X 78747709-78757094 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA046563, HPA054951, HPA055571 Uncertain Supported Nuclear bodies
Vesicles
Plasma membrane Tissue enhanced Tissue enhanced ovary: 4.5 cerebral cortex: 2.2 Cell line enhanced AF22: 9.2;NTERA-2: 15.2;RH-30: 6.2 +EBP CDPX2, CHO2, CPX, CPXD ENSG00000147155 Emopamil binding protein (sterol isomerase) X 48521158-48528716 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA003130 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all liver: 91.3 Expressed in all +AWAT2 DGAT2L4, MFAT ENSG00000147160 Acyl-CoA wax alcohol acyltransferase 2 X 70040542-70049938 Enzymes, Predicted membrane proteins Evidence at protein level HPA062748 Approved Tissue enriched Tissue enhanced breast: 2.0;skin: 1.2 testis: 0.5 Not detected +OGT FLJ23071, HRNT1, MGC22921, O-GLCNAC ENSG00000147162 O-linked N-acetylglucosamine (GlcNAc) transferase X 71533083-71575897 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA030751, HPA030752, HPA030753, HPA030754, CAB034099 Approved Supported Nucleoplasm
Plasma membrane Urothelial cancer:6.85e-7 (favourable), Renal cancer:2.36e-6 (unfavourable), Head and neck cancer:1.97e-4 (favourable), Endometrial cancer:8.33e-4 (unfavourable) Expressed in all Expressed in all spleen: 83.2 Expressed in all +SNX12 ENSG00000147164 Sorting nexin 12 X 71056332-71073426 Predicted intracellular proteins Evidence at protein level CAB070423 Approved Renal cancer:1.51e-7 (favourable), Endometrial cancer:1.17e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 59.0 Expressed in all +ITGB1BP2 CHORDC3 ENSG00000147166 Integrin subunit beta 1 binding protein 2 X 71301734-71305371 Predicted intracellular proteins Evidence at protein level HPA040721 Approved Cytosol Mixed Tissue enhanced heart muscle: 52.9;smooth muscle: 23.1 skeletal muscle: 16.0 Cell line enhanced HMC-1: 8.1 +IL2RG CD132, CIDX, IMD4, SCIDX1 ENSG00000147168 Interleukin 2 receptor subunit gamma X 71107404-71112108 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046641, HPA049691 Enhanced Approved Vesicles Renal cancer:2.28e-7 (unfavourable), Endometrial cancer:1.73e-4 (favourable) Expressed in all Tissue enhanced lymph node: 273.3;tonsil: 279.4 appendix: 182.3 Cell line enriched 5 Karpas-707: 1646.4 +GCNA ACRC, NAAR1 ENSG00000147174 Germ cell nuclear acidic peptidase X 71578411-71613583 Predicted intracellular proteins Evidence at protein level HPA023476 Enhanced Approved Vesicles Mixed Group enriched 5 adrenal gland: 5.9;testis: 20.6 spleen: 2.4 Mixed +ZNF711 CMPX1, dJ75N13.1, MRX97, Zfp711, ZNF4, ZNF5, ZNF6 ENSG00000147180 Zinc finger protein 711 X 85244032-85273362 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030654 Enhanced Approved Nucleoplasm Mixed Tissue enhanced testis: 69.8 cerebral cortex: 32.7 Cell line enhanced AF22: 34.0;HAP1: 51.8;HEK 293: 42.5;RH-30: 40.6 +CPXCR1 CT77 ENSG00000147183 CPX chromosome region, candidate 1 X 88747225-88754785 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 57 testis: 11.5 fallopian tube: 0.2 Not detected +DIAPH2 DIA, DIA2, POF, POF2 ENSG00000147202 Diaphanous related formin 2 X 96684663-97604997 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005647, CAB015461, CAB068183, CAB068184 Enhanced Supported Nucleoli
Endoplasmic reticulum
Vesicles Endometrial cancer:2.16e-5 (unfavourable), Pancreatic cancer:2.12e-4 (unfavourable), Renal cancer:3.90e-4 (unfavourable) Expressed in all Expressed in all placenta: 17.8 Mixed +NXF3 ENSG00000147206 Nuclear RNA export factor 3 X 103075810-103093125 Predicted intracellular proteins Evidence at protein level HPA003132, HPA046757 Approved Supported Nucleoplasm Mixed Tissue enhanced fallopian tube: 39.8;testis: 71.8 epididymis: 13.5 Cell line enhanced HEL: 44.1;HL-60: 37.4;U-2197: 127.8;U-937: 80.9 +RIPPLY1 ENSG00000147223 Ripply transcriptional repressor 1 X 106900063-106903335 Predicted secreted proteins Evidence at protein level HPA052284 Uncertain Group enriched Tissue enhanced kidney: 2.3;liver: 3.0 seminal vesicle: 1.2 Cell line enriched 11 RH-30: 6.3 +PRPS1 CMTX5, DFN2, DFNX1 ENSG00000147224 Phosphoribosyl pyrophosphate synthetase 1 X 107628424-107651026 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043760 Uncertain Approved Cytosol Expressed in all Expressed in all thyroid gland: 73.9 Expressed in all +CXorf57 FLJ10178, FLJ14191 ENSG00000147231 Chromosome X open reading frame 57 X 106611930-106679442 Predicted intracellular proteins Evidence at protein level HPA000896, HPA001374 Uncertain Approved Intermediate filaments Mixed Mixed adrenal gland: 9.4 Cell line enhanced HEK 293: 34.2;RT4: 31.7 +FRMPD3 KIAA1817, RP5-1070B1.1 ENSG00000147234 FERM and PDZ domain containing 3 X 107522450-107605251 Predicted intracellular proteins Evidence at transcript level HPA003164 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 5.9;ovary: 6.7;thyroid gland: 5.5 seminal vesicle: 1.9 Cell line enhanced Daudi: 4.2;SCLC-21H: 2.1;WM-115: 2.1 +HTR2C 5-HT2C, 5HTR2C, HTR1C ENSG00000147246 5-hydroxytryptamine receptor 2C X 114584078-114910061 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enriched 6 cerebral cortex: 3.1 cervix, uterine: 0.5 Cell line enhanced EFO-21: 2.5;U-266/70: 3.6;U-266/84: 2.8 +DOCK11 ACG, FLJ32122, FLJ43653, ZIZ2 ENSG00000147251 Dedicator of cytokinesis 11 X 118495898-118686163 Predicted intracellular proteins Evidence at protein level HPA059695 Uncertain Approved Nuclear membrane
Nucleoli Head and neck cancer:4.87e-4 (favourable) Expressed in all Mixed adipose tissue: 34.0 Cell line enhanced HMC-1: 81.5 +IGSF1 IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2 ENSG00000147255 Immunoglobulin superfamily member 1 X 131273506-131578899 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012732, HPA035582 Enhanced Approved Cytosol Endometrial cancer:4.25e-8 (unfavourable) Tissue enriched Tissue enhanced testis: 20.0 adrenal gland: 13.1 Cell line enhanced Hep G2: 22.7;SH-SY5Y: 30.6 +ARHGAP36 FLJ30058 ENSG00000147256 Rho GTPase activating protein 36 X 131058242-131089883 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002064 Enhanced Approved Nucleus
Vesicles
Plasma membrane Tissue enriched Tissue enriched 19 adrenal gland: 137.8 cerebral cortex: 7.4 Cell line enriched 173 SH-SY5Y: 188.2 +GPC3 DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1 ENSG00000147257 Glypican 3 X 133535745-133985895 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006316 Approved Plasma membrane Stomach cancer:4.83e-4 (unfavourable) Expressed in all Tissue enriched 6 placenta: 845.0 lung: 130.6 Group enriched 6 HAP1: 539.0;Hep G2: 1445.8 +GPR119 GPCR2, hGPCR2 ENSG00000147262 G protein-coupled receptor 119 X 130384440-130385447 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Pancreatic cancer:6.93e-4 (favourable) Tissue enriched Not detected pancreas: 0.6 Cell line enhanced Hep G2: 1.1 +RBMX hnRNP-G, HNRNPG, RNMX ENSG00000147274 RNA binding motif protein, X-linked X 136848004-136880764 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA057707 Supported Approved Nucleoplasm Liver cancer:5.16e-6 (unfavourable) Expressed in all Expressed in all ovary: 296.7 Expressed in all +MCPH1 BRIT1, FLJ12847 ENSG00000147316 Microcephalin 1 8 6406592-6648504 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008238, CAB012177 Supported Uncertain Nucleoplasm
Nuclear bodies Colorectal cancer:8.52e-4 (favourable) Expressed in all Expressed in all testis: 19.5 Expressed in all +MFHAS1 LRRC65, MASL1 ENSG00000147324 Malignant fibrous histiocytoma amplified sequence 1 8 8783354-8893645 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051213, HPA054471 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Mixed spleen: 16.6 Cell line enhanced MOLT-4: 111.7 +FBXO25 FBX25 ENSG00000147364 F-box protein 25 8 406428-477967 Disease related genes, Predicted intracellular proteins Evidence at protein level Cervical cancer:5.38e-5 (favourable), Renal cancer:1.41e-4 (favourable) Expressed in all Expressed in all testis: 151.3 Mixed +FATE1 CT43, FATE ENSG00000147378 Fetal and adult testis expressed 1 X 151716035-151723194 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034604 Enhanced Renal cancer:2.88e-4 (unfavourable) Group enriched Tissue enriched 314 testis: 308.4 cerebral cortex: 0.9 Not detected +MAGEA4 CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336 ENSG00000147381 MAGE family member A4 X 151912509-151925170 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021942, CAB040535 Enhanced Approved Nuclear speckles
Cytosol Mixed Tissue enriched 7 testis: 44.7 placenta: 6.3 Cell line enhanced A-431: 382.3;AN3-CA: 243.7;HMC-1: 436.2;U-266/84: 580.0 +NSDHL H105e3, SDR31E1, XAP104 ENSG00000147383 NAD(P) dependent steroid dehydrogenase-like X 152830967-152869729 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000248, HPA000571 Enhanced Enhanced Endoplasmic reticulum
Lipid droplets Renal cancer:6.09e-5 (favourable), Liver cancer:5.04e-4 (unfavourable), Cervical cancer:5.65e-4 (favourable) Expressed in all Expressed in all epididymis: 54.1 Expressed in all +ZNF185 SCELL ENSG00000147394 Zinc finger protein 185 (LIM domain) X 152914442-152973480 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000400, HPA016438 Enhanced Supported Plasma membrane
Actin filaments
Focal adhesion sites
Cytosol Pancreatic cancer:3.30e-5 (unfavourable), Lung cancer:1.50e-4 (unfavourable) Expressed in all Tissue enhanced epididymis: 400.1;esophagus: 278.4;seminal vesicle: 202.3 cervix, uterine: 105.3 Cell line enhanced A-431: 108.1;EFO-21: 131.6;TIME: 192.3 +CETN2 CALT, CEN2 ENSG00000147400 Centrin 2 X 152826973-152830777 Predicted intracellular proteins Evidence at protein level HPA028956 Uncertain Cervical cancer:7.54e-6 (favourable), Ovarian cancer:9.97e-4 (favourable) Expressed in all Expressed in all fallopian tube: 374.6 Expressed in all +RPL10 DXS648, DXS648E, FLJ23544, L10, NOV, QM ENSG00000147403 Ribosomal protein L10 X 154389955-154409168 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level CAB010339, HPA011311 Enhanced Enhanced Endoplasmic reticulum
Cytosol Renal cancer:7.67e-6 (unfavourable) Expressed in all Expressed in all ovary: 9682.7 Expressed in all +CSGALNACT1 ChGn, CSGalNAcT-1, FLJ11264 ENSG00000147408 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 8 19404161-19758029 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA061336 Supported Actin filaments Expressed in all Expressed in all thyroid gland: 145.2 Cell line enhanced A549: 52.2;BJ hTERT+: 26.0;RPTEC TERT1: 29.9;U-2197: 33.6;U-87 MG: 25.2 +ATP6V1B2 ATP6B2, HO57, VATB, Vma2, VPP3 ENSG00000147416 ATPase H+ transporting V1 subunit B2 8 20197367-20226819 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA008147 Enhanced Supported Vesicles Renal cancer:8.41e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 304.2 Expressed in all +CCDC25 FLJ10853 ENSG00000147419 Coiled-coil domain containing 25 8 27733311-27772653 Predicted intracellular proteins Evidence at protein level HPA023256 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:1.11e-7 (favourable) Expressed in all Expressed in all duodenum: 35.6 Expressed in all +HMBOX1 FLJ21616, HNF1LA, HOT1, PBHNF ENSG00000147421 Homeobox containing 1 8 28890394-29064764 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055855, HPA058586, CAB070418 Enhanced Enhanced Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Mixed testis: 13.9 Expressed in all +CHRNB3 ENSG00000147432 Cholinergic receptor nicotinic beta 3 subunit 8 42697376-42737407 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045555 Enhanced Tissue enriched Tissue enhanced testis: 2.6 cerebral cortex: 0.6 Cell line enhanced NTERA-2: 1.1;U-266/84: 1.8 +CHRNA6 ENSG00000147434 Cholinergic receptor nicotinic alpha 6 subunit 8 42752620-42796392 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Mixed Not detected adrenal gland,fallopian tube: 0.5 Cell line enhanced Daudi: 3.0;HDLM-2: 2.5;HMC-1: 1.1;U-698: 2.5 +GNRH1 GNRH, GRH, LHRH ENSG00000147437 Gonadotropin releasing hormone 1 8 25419260-25424654 Disease related genes, Predicted secreted proteins Evidence at protein level HPA027532 Supported Renal cancer:8.08e-9 (unfavourable) Mixed Mixed skin: 10.4 Cell line enriched 5 SCLC-21H: 23.9 +BIN3 ENSG00000147439 Bridging integrator 3 8 22620418-22669148 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023769 Approved Expressed in all Mixed bone marrow: 25.5 Expressed in all +DOK2 Dok-2, p56dok-2 ENSG00000147443 Docking protein 2 8 21908873-21913860 Predicted intracellular proteins Evidence at protein level CAB004379, HPA066571 Enhanced Renal cancer:2.20e-4 (unfavourable), Melanoma:4.31e-4 (favourable) Expressed in all Mixed spleen: 35.0 Group enriched 9 HDLM-2: 23.7;HEL: 48.6;HMC-1: 98.0;THP-1: 28.2;U-937: 31.6 +SLC25A37 HT015, MFRN, MFRN1, MSCP ENSG00000147454 Solute carrier family 25 member 37 8 23528805-23575463 Predicted intracellular proteins, Transporters Evidence at protein level HPA045680 Uncertain Renal cancer:4.37e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 80.1 Expressed in all +CHMP7 MGC29816 ENSG00000147457 Charged multivesicular body protein 7 8 23243637-23262000 Predicted intracellular proteins Evidence at protein level HPA036119 Uncertain Supported Nucleus
Cytosol Expressed in all Tissue enhanced lymph node: 38.5 tonsil: 25.3 Expressed in all +DOCK5 FLJ21034 ENSG00000147459 Dedicator of cytokinesis 5 8 25184723-25418082 Predicted intracellular proteins Evidence at protein level HPA017719, HPA056837 Approved Enhanced Cytosol Renal cancer:1.18e-6 (unfavourable), Endometrial cancer:1.91e-4 (favourable) Expressed in all Mixed spleen: 18.6 Mixed +STAR StAR, STARD1 ENSG00000147465 Steroidogenic acute regulatory protein 8 38143649-38151265 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023644, HPA027318, CAB032598 Enhanced Tissue enhanced Tissue enriched 12 adrenal gland: 2879.8 ovary: 245.8 Group enriched 7 HEL: 92.1;K-562: 433.7 +PROSC ENSG00000147471 Proline synthetase cotranscribed homolog (bacterial) 8 37762593-37779767 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB017033, HPA023646, HPA023733 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 59.4 Expressed in all +ERLIN2 C8orf2, Erlin-2, NET32, SPFH2, SPG18 ENSG00000147475 ER lipid raft associated 2 8 37736599-37759101 Disease related genes, Predicted secreted proteins Evidence at protein level HPA002025, CAB014894 Enhanced Supported Endoplasmic reticulum Renal cancer:6.67e-6 (favourable), Glioma:1.96e-4 (unfavourable), Colorectal cancer:5.16e-4 (favourable) Expressed in all Expressed in all thyroid gland: 80.9 Expressed in all +SNTG1 G1SYN, SYN4 ENSG00000147481 Syntrophin gamma 1 8 49909789-50794118 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA072282 Supported Tissue enhanced Tissue enhanced cerebral cortex: 8.6;spleen: 3.8 testis: 1.2 Not detected +PXDNL FLJ25471, PMR1 ENSG00000147485 Peroxidasin like 8 51319578-51809445 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007919 Approved Nucleoplasm
Cytosol Breast cancer:3.27e-5 (unfavourable) Mixed Group enriched 8 epididymis: 11.5;heart muscle: 24.1;testis: 9.0 adipose tissue: 1.8 Group enriched 7 AF22: 7.6;Daudi: 4.2;SH-SY5Y: 6.5 +ST18 KIAA0535, NZF3, ZC2H2C3, ZC2HC10, ZNF387 ENSG00000147488 ST18, C2H2C-type zinc finger 8 52110839-52460959 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044919 Uncertain Tissue enhanced Tissue enriched 7 cerebral cortex: 11.6 stomach: 1.5 Cell line enhanced HAP1: 2.8;SCLC-21H: 11.3;U-87 MG: 1.5 +RGS20 RGSZ1, ZGAP1 ENSG00000147509 Regulator of G-protein signaling 20 8 53851808-53959303 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA070193 Enhanced Tissue enhanced Tissue enhanced cerebral cortex: 10.1 thyroid gland: 2.1 Cell line enhanced SK-MEL-30: 23.4;U-87 MG: 28.2 +TACC1 ENSG00000147526 Transforming acidic coiled-coil containing protein 1 8 38728186-38853028 Predicted intracellular proteins Evidence at protein level CAB017041, HPA024702 Approved Renal cancer:1.06e-5 (favourable) Expressed in all Expressed in all adipose tissue: 166.8 Expressed in all +GOLGA7 GCP16, GOLGA3AP1, GOLGA7A, HSPC041 ENSG00000147533 Golgin A7 8 41490396-41510980 Predicted intracellular proteins Evidence at protein level HPA046878 Uncertain Endometrial cancer:1.36e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 96.4 Expressed in all +PLPP5 DPPL1, HTPAP, PPAPDC1B ENSG00000147535 Phospholipid phosphatase 5 8 38263130-38269243 Enzymes, Predicted membrane proteins Evidence at protein level HPA055777 Approved Vesicles Renal cancer:8.33e-10 (unfavourable), Endometrial cancer:1.48e-5 (favourable), Ovarian cancer:2.42e-5 (favourable), Lung cancer:8.72e-5 (favourable) Expressed in all Expressed in all prostate: 120.8 Mixed +GINS4 MGC14799, SLD5 ENSG00000147536 GINS complex subunit 4 8 41529206-41545046 Predicted intracellular proteins Evidence at protein level HPA024663, HPA026580 Uncertain Supported Nucleoplasm
Centrosome Endometrial cancer:2.30e-5 (unfavourable) Mixed Mixed lymph node: 6.2 Mixed +NSD3 FLJ20353, KMT3F, WHISTLE, WHSC1L1 ENSG00000147548 Nuclear receptor binding SET domain protein 3 8 38269697-38382272 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005659, CAB013721, HPA018893 Uncertain Approved Nucleoplasm
Mitochondria Pancreatic cancer:7.48e-4 (unfavourable) Expressed in all Expressed in all placenta: 47.8 Expressed in all +DNAJC5B CSP-beta, MGC26226 ENSG00000147570 DnaJ heat shock protein family (Hsp40) member C5 beta 8 66021560-66100526 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA077389 Approved Vesicles Mixed Tissue enriched 13 testis: 114.3 lung: 9.1 Group enriched 6 HDLM-2: 17.3;RPTEC TERT1: 15.6;THP-1: 8.8;U-266/70: 8.7;U-937: 8.8 +CRH CRF, CRH1 ENSG00000147571 Corticotropin releasing hormone 8 66176382-66178725 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA046846, HPA062111 Uncertain Supported Tissue enriched Tissue enhanced cerebral cortex: 2.1;placenta: 8.0 adipose tissue: 1.2 Not detected +TRIM55 MURF-2, RNF29 ENSG00000147573 Tripartite motif containing 55 8 66126896-66175487 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038793, HPA053691 Approved Approved Golgi apparatus
Cytosol Group enriched Tissue enhanced heart muscle: 40.0;liver: 19.7 testis: 13.2 Cell line enriched 17 LHCN-M2: 356.6 +ADHFE1 ADHFe1, FLJ32430 ENSG00000147576 Alcohol dehydrogenase, iron containing 1 8 66430185-66471601 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023062 Enhanced Approved Vesicles Renal cancer:4.55e-5 (favourable), Breast cancer:5.76e-5 (favourable), Liver cancer:9.90e-5 (favourable) Mixed Mixed liver: 14.3 Cell line enhanced ASC diff: 1.1;RPTEC TERT1: 1.2 +MRPS28 HSPC007, MRP-S28, MRPS35 ENSG00000147586 Mitochondrial ribosomal protein S28 8 79918717-80030289 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA027202 Approved Enhanced Mitochondria Renal cancer:1.20e-6 (favourable) Expressed in all Expressed in all adrenal gland: 114.1 Expressed in all +PMP2 FABP8, M-FABP, MP2 ENSG00000147588 Peripheral myelin protein 2 8 81440326-81447523 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 55 cerebral cortex: 288.6 seminal vesicle: 5.2 Cell line enhanced WM-115: 1.3 +LACTB2 CGI-83 ENSG00000147592 Lactamase beta 2 8 70635318-70669174 Predicted intracellular proteins Evidence at protein level HPA044391, HPA053040 Approved Supported Nucleus
Golgi apparatus
Cytosol Renal cancer:5.60e-4 (favourable) Expressed in all Expressed in all testis: 119.4 Cell line enhanced SK-BR-3: 329.9 +PRDM14 ENSG00000147596 PR/SET domain 14 8 70051651-70071693 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019094, HPA057070 Uncertain Uncertain Nucleoplasm Tissue enriched Tissue enhanced testis: 1.7 skin: 0.5 Cell line enriched 101 NTERA-2: 50.3 +TERF1 PIN2, TRBF1, TRF, TRF1 ENSG00000147601 Telomeric repeat binding factor 1 8 73008864-73048122 Predicted intracellular proteins Evidence at protein level HPA048379 Supported Nucleoli fibrillar center
Nuclear bodies Renal cancer:6.68e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 45.8 Expressed in all +RPL7 humL7-1, L7 ENSG00000147604 Ribosomal protein L7 8 73290267-73295789 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA058373 Approved Approved Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 5525.6 Expressed in all +SLC26A7 SUT2 ENSG00000147606 Solute carrier family 26 member 7 8 91209494-91398152 Predicted membrane proteins Evidence at transcript level Group enriched Tissue enriched 21 thyroid gland: 550.6 kidney: 26.3 Not detected +PSKH2 ENSG00000147613 Protein serine kinase H2 8 86048373-86088621 Enzymes, Predicted membrane proteins Evidence at protein level HPA015095 Uncertain Tissue enhanced Not detected testis: 0.4 Cell line enriched 21 HEL: 8.2 +ATP6V0D2 ATP6D2, FLJ38708, VMA6 ENSG00000147614 ATPase H+ transporting V0 subunit d2 8 85987323-86154228 Predicted intracellular proteins Evidence at protein level HPA055327, HPA058496 Enhanced Approved Vesicles Renal cancer:2.20e-6 (favourable) Tissue enriched Tissue enriched 15 kidney: 59.4 rectum: 3.9 Cell line enhanced SCLC-21H: 2.3;SK-MEL-30: 2.6;U-87 MG: 4.8 +SYBU FLJ20366, GOLSYN, KIAA1472, OCSYN, SNPHL ENSG00000147642 Syntabulin 8 109573978-109691791 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053057 Uncertain Supported Vesicles Liver cancer:7.74e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 76.0 adrenal gland: 40.7 Cell line enhanced HaCaT: 20.2;PC-3: 23.7;SCLC-21H: 20.0;SK-BR-3: 38.8 +DPYS DHPase ENSG00000147647 Dihydropyrimidinase 8 104330324-104467053 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA024785 Enhanced Group enriched Group enriched 22 kidney: 200.4;liver: 246.2 gallbladder: 10.1 Not detected +MTDH 3D3, AEG-1, LYRIC ENSG00000147649 Metadherin 8 97644179-97728770 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010932, HPA015104, CAB068204, CAB068205 Supported Enhanced Endoplasmic reticulum Renal cancer:3.82e-4 (unfavourable), Pancreatic cancer:5.36e-4 (unfavourable), Lung cancer:7.76e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 104.4 Expressed in all +LRP12 FLJ12929, ST7 ENSG00000147650 LDL receptor related protein 12 8 104489231-104589024 Predicted membrane proteins Evidence at protein level HPA017245 Uncertain Approved Nucleoli fibrillar center
Plasma membrane
Mitochondria Endometrial cancer:2.67e-4 (unfavourable) Expressed in all Mixed endometrium: 27.8 Mixed +EBAG9 EB9, RCAS1 ENSG00000147654 Estrogen receptor binding site associated, antigen, 9 8 109539711-109565996 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021153, HPA021154, CAB072810, CAB072811, CAB072812 Enhanced Enhanced Golgi apparatus Expressed in all Expressed in all thyroid gland: 96.5 Expressed in all +RSPO2 MGC35555 ENSG00000147655 R-spondin 2 8 107899316-108083648 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA024764, CAB025900, HPA053068 Approved Mixed Tissue enhanced cerebral cortex: 20.2;placenta: 25.7 prostate: 15.8 Cell line enhanced HEK 293: 1.7;HEL: 1.6;NTERA-2: 1.0;U-138 MG: 1.8;U-266/70: 4.2 +POLR2K RPB10alpha ENSG00000147669 RNA polymerase II subunit K 8 100150584-100154002 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA063185 Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all thyroid gland: 98.4 Expressed in all +MAL2 ENSG00000147676 Mal, T-cell differentiation protein 2 (gene/pseudogene) 8 119165034-119245673 Predicted membrane proteins Evidence at protein level HPA043831 Uncertain Breast cancer:4.57e-6 (unfavourable), Renal cancer:2.39e-5 (favourable), Endometrial cancer:8.44e-5 (unfavourable), Pancreatic cancer:3.98e-4 (unfavourable) Expressed in all Mixed esophagus: 266.5 Cell line enhanced A-431: 909.7;HaCaT: 399.9;SK-BR-3: 1080.1 +EIF3H eIF3-gamma, eIF3-p40, eIF3h, EIF3S3 ENSG00000147677 Eukaryotic translation initiation factor 3 subunit H 8 116642130-116766925 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA023117, HPA023553 Approved Approved Cytosol Breast cancer:5.26e-4 (unfavourable), Cervical cancer:8.07e-4 (unfavourable), Liver cancer:8.34e-4 (unfavourable) Expressed in all Expressed in all ovary: 480.9 Expressed in all +UTP23 C8orf53, MGC14595 ENSG00000147679 UTP23, small subunit processome component 8 116766503-116849463 Predicted intracellular proteins Evidence at protein level HPA044418 Uncertain Approved Nucleoli Breast cancer:5.18e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 21.2 Expressed in all +NDUFB9 B22, LYRM3, UQOR22 ENSG00000147684 NADH:ubiquinone oxidoreductase subunit B9 8 124539103-124568510 Predicted intracellular proteins Evidence at protein level HPA042768 Approved Supported Mitochondria Renal cancer:3.42e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 443.1 Expressed in all +TATDN1 CDA11 ENSG00000147687 TatD DNase domain containing 1 8 124488485-124539458 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023634, HPA053045 Uncertain Supported Nucleoplasm Pancreatic cancer:2.53e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 62.1 Expressed in all +FAM83A BJ-TSA-9, MGC14128 ENSG00000147689 Family with sequence similarity 83 member A 8 123178960-123210079 Predicted intracellular proteins Evidence at protein level HPA052615 Approved Nucleoplasm Lung cancer:2.98e-9 (unfavourable), Pancreatic cancer:4.99e-6 (unfavourable), Endometrial cancer:3.85e-4 (unfavourable) Tissue enhanced Tissue enriched 8 esophagus: 77.9 seminal vesicle: 9.3 Cell line enhanced A-431: 72.5;HBEC3-KT: 90.5;hTCEpi: 47.9;K-562: 183.8 +GSDMC MLZE ENSG00000147697 Gasdermin C 8 129748196-129786888 Predicted intracellular proteins, Transporters Evidence at protein level HPA023670, HPA024767, HPA026317 Supported Enhanced Mitochondria Group enriched Tissue enhanced esophagus: 20.0;skin: 44.3;spleen: 21.6 tonsil: 6.5 Cell line enhanced A-431: 13.0;HaCaT: 3.1;hTCEpi: 4.5;HUVEC TERT2: 5.2;TIME: 4.3 +FAM135B C8ORFK32 ENSG00000147724 Family with sequence similarity 135 member B 8 138130023-138496822 Predicted intracellular proteins Evidence at transcript level HPA023911, HPA023950, HPA024815 Uncertain Approved Nucleoplasm
Nuclear membrane Tissue enhanced Group enriched 8 adrenal gland: 3.6;cerebral cortex: 8.3;testis: 7.3 colon: 0.8 Cell line enriched 11 RH-30: 8.5 +ZNF7 HF.16, KOX4 ENSG00000147789 Zinc finger protein 7 8 144827464-144847509 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030296, HPA059090 Uncertain Approved Mitochondria Renal cancer:8.46e-8 (unfavourable) Expressed in all Expressed in all testis: 31.3 Expressed in all +ARHGAP39 CrGAP, KIAA1688, Vilse ENSG00000147799 Rho GTPase activating protein 39 8 144529179-144605816 Predicted intracellular proteins Evidence at protein level HPA044491 Approved Nucleoplasm
Microtubules
Cytokinetic bridge
Cytosol Expressed in all Tissue enhanced testis: 16.4 cerebral cortex,fallopian tube: 7.3 Mixed +SLC39A4 AEZ, AWMS2, ZIP4 ENSG00000147804 Solute carrier family 39 member 4 8 144409742-144416895 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Renal cancer:9.04e-4 (favourable) Expressed in all Group enriched 8 duodenum: 134.2;small intestine: 95.7 kidney: 14.3 Group enriched 9 CAPAN-2: 50.5;Hep G2: 102.1 +NAPRT NAPRT1, PP3856 ENSG00000147813 Nicotinate phosphoribosyltransferase 8 143574785-143578649 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023739, HPA024017, CAB068206, CAB068207 Enhanced Approved Nucleus
Golgi apparatus
Cytosol Renal cancer:6.28e-4 (favourable) Expressed in all Tissue enhanced duodenum: 21.4;small intestine: 20.7 bone marrow: 9.6 Cell line enhanced CAPAN-2: 33.3;SK-BR-3: 30.1 +VLDLR CARMQ1, CHRMQ1, VLDLRCH ENSG00000147852 Very low density lipoprotein receptor 9 2621834-2660053 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB032462, HPA051312 Uncertain Approved Vesicles
Cytokinetic bridge
Microtubule organizing center Endometrial cancer:5.95e-4 (favourable) Expressed in all Tissue enhanced ovary: 110.0;parathyroid gland: 124.0 fallopian tube: 43.7 Cell line enhanced BEWO: 60.5 +AK3 AK3L1, AK6, AKL3L1 ENSG00000147853 Adenylate kinase 3 9 4709559-4742043 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063324 Enhanced Supported Mitochondria Renal cancer:6.07e-9 (favourable) Expressed in all Expressed in all kidney: 106.2 Expressed in all +UHRF2 MGC33463, NIRF, RNF107, TDRD23, URF2 ENSG00000147854 Ubiquitin like with PHD and ring finger domains 2 9 6413151-6507054 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026633, HPA026697 Enhanced Nucleoplasm Expressed in all Expressed in all bone marrow: 32.8 Expressed in all +NFIB NFI-RED, NFIB2, NFIB3 ENSG00000147862 Nuclear factor I B 9 14081843-14398983 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003956 Supported Supported Nucleus
Nucleoli fibrillar center Renal cancer:3.53e-4 (favourable) Expressed in all Mixed breast: 44.5 Cell line enhanced AN3-CA: 151.3 +CER1 DAND4 ENSG00000147869 Cerberus 1, DAN family BMP antagonist 9 14719724-14722717 Predicted secreted proteins Evidence at protein level HPA019917 Uncertain Tissue enriched Tissue enriched 6 epididymis: 1.3 endometrium: 0.2 Group enriched 10 HEL: 3.6;NTERA-2: 7.1;SCLC-21H: 3.2 +PLIN2 ADFP, ADRP ENSG00000147872 Perilipin 2 9 19108375-19149290 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016607, CAB037331 Supported Supported Lipid droplets Thyroid cancer:2.16e-4 (favourable), Renal cancer:3.32e-4 (unfavourable) Group enriched Expressed in all liver: 450.7 Cell line enhanced ASC diff: 1543.1;HHSteC: 1631.5 +IFNA5 IFN-alphaG ENSG00000147873 Interferon alpha 5 9 21304326-21305312 Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected epididymis: 0.2 Not detected +HAUS6 dgt6, FAM29A, FLJ20060, KIAA1574 ENSG00000147874 HAUS augmin like complex subunit 6 9 19053143-19103119 Predicted intracellular proteins Evidence at protein level HPA020960, HPA020965 Approved Supported Nuclear speckles
Microtubule organizing center
Cytosol Renal cancer:3.13e-5 (unfavourable), Liver cancer:3.84e-4 (unfavourable) Expressed in all Tissue enhanced testis: 43.2 lymph node: 13.3 Expressed in all +CDKN2B CDK4I, INK4B, MTS2, P15, p15INK4b, TP15 ENSG00000147883 Cyclin dependent kinase inhibitor 2B 9 22002903-22009363 Predicted intracellular proteins Evidence at protein level CAB000349, HPA052838, HPA063327 Uncertain Approved Nucleoplasm Endometrial cancer:4.47e-6 (unfavourable), Renal cancer:1.03e-4 (unfavourable), Liver cancer:1.49e-4 (unfavourable) Expressed in all Mixed small intestine: 32.6 Cell line enhanced HaCaT: 30.4;SiHa: 46.3 +IFNA16 IFN-alphaO ENSG00000147885 Interferon alpha 16 9 21216373-21217311 Predicted secreted proteins Evidence at transcript level HPA047557 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +CDKN2A ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf ENSG00000147889 Cyclin dependent kinase inhibitor 2A 9 21967753-21995301 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000093, CAB000445, CAB018232, HPA047838 Uncertain Enhanced Nucleoli Endometrial cancer:1.82e-7 (unfavourable), Renal cancer:5.76e-7 (unfavourable), Liver cancer:2.17e-4 (unfavourable), Head and neck cancer:5.19e-4 (favourable) Expressed in all Mixed parathyroid gland: 7.5 Cell line enhanced HEK 293: 297.6 +C9orf72 DENNL72, MGC23980 ENSG00000147894 Chromosome 9 open reading frame 72 9 27546545-27573866 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023873 Uncertain Expressed in all Expressed in all testis: 32.1 Mixed +IFNK ENSG00000147896 Interferon kappa 9 27524314-27526498 Predicted intracellular proteins Evidence at protein level Group enriched Not detected skin: 0.1 Not detected +ZCCHC7 AIR1, FLJ22611 ENSG00000147905 Zinc finger CCHC-type containing 7 9 37120539-37358149 Predicted intracellular proteins Evidence at protein level HPA020600, HPA021088, HPA029522 Uncertain Enhanced Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 28.4 Expressed in all +FBXO10 FBX10 ENSG00000147912 F-box protein 10 9 37510892-37576349 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA002863, HPA072721 Uncertain Approved Nucleus
Cytosol Expressed in all Mixed testis: 16.4 Cell line enhanced HHSteC: 29.5 +SIGMAR1 OPRS1, SR-BP1 ENSG00000147955 Sigma non-opioid intracellular receptor 1 9 34634722-34637809 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB013470, HPA018002, HPA024071 Approved Urothelial cancer:3.42e-4 (unfavourable) Expressed in all Expressed in all liver: 67.8 Expressed in all +CBWD5 ENSG00000147996 COBW domain containing 5 9 65668805-65734041 Predicted intracellular proteins Evidence at transcript level HPA042759, HPA042813 Approved Approved Plasma membrane Mixed Expressed in all breast: 22.0 Expressed in all +CEP78 C9orf81, FLJ12643 ENSG00000148019 Centrosomal protein 78 9 78236062-78279690 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA048846 Approved Expressed in all Tissue enhanced testis: 30.7 endometrium,parathyroid gland: 9.9 Expressed in all +NTRK2 TRKB ENSG00000148053 Neurotrophic receptor tyrosine kinase 2 9 84668551-85027070 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA007637, CAB010346 Enhanced Approved Cytosol Group enriched Tissue enhanced cerebral cortex: 439.6;thyroid gland: 215.7 breast: 82.1 Group enriched 5 AF22: 9.4;HaCaT: 3.1;RPTEC TERT1: 8.1;SH-SY5Y: 12.9;WM-115: 2.8 +IDNK bA522I20.2, C9orf103, hGntK ENSG00000148057 IDNK, gluconokinase 9 83623049-83644130 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020378, HPA058429 Enhanced Approved Mitochondria
Cytosol Endometrial cancer:1.10e-6 (favourable) Expressed in all Mixed kidney: 50.5 Mixed +SHC3 N-Shc, NSHC, SHCC ENSG00000148082 SHC adaptor protein 3 9 89005771-89178767 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA031427, HPA046656, HPA072448 Uncertain Enhanced Nucleoplasm
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 45.3 parathyroid gland: 12.6 Cell line enhanced AF22: 20.5;SH-SY5Y: 8.1;U-87 MG: 11.2 +AUH ENSG00000148090 AU RNA binding methylglutaconyl-CoA hydratase 9 91213815-91361913 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA004171 Enhanced Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all kidney: 65.4 Expressed in all +MFSD14B FLJ14753, HIATL1 ENSG00000148110 Major facilitator superfamily domain containing 14B 9 94374551-94461042 Predicted membrane proteins, Transporters Evidence at protein level HPA017978 Approved Nucleoplasm
Cytosol Expressed in all Tissue enriched 5 parathyroid gland: 255.7 skin: 50.6 Expressed in all +C9orf3 AOPEP, AP-O, APO, C90RF3, FLJ14675 ENSG00000148120 Chromosome 9 open reading frame 3 9 94726701-95087218 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004633, HPA072729 Approved Approved Cell Junctions Renal cancer:6.33e-5 (favourable) Expressed in all Expressed in all skin: 50.0 Mixed +PLPPR1 FLJ20300, LPPR1, MGC26189, PRG-3 ENSG00000148123 Phospholipid phosphatase related 1 9 101028709-101325135 Predicted membrane proteins Evidence at protein level HPA014760, HPA014968, HPA014979 Supported Supported Nucleoplasm Lung cancer:1.37e-4 (favourable) Group enriched Group enriched 6 cerebral cortex: 23.8;kidney: 15.8 epididymis: 3.3 Cell line enhanced Hep G2: 2.1;SCLC-21H: 6.4 +OR13C4 ENSG00000148136 Olfactory receptor family 13 subfamily C member 4 9 104526253-104527209 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF462 DKFZP762N2316, KIAA1803, Zfp462 ENSG00000148143 Zinc finger protein 462 9 106863097-107013634 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA022283 Uncertain Approved Nucleoplasm Renal cancer:6.19e-4 (favourable) Mixed Mixed parathyroid gland: 15.9 Mixed +INIP C9orf80, HSPC043, hSSBIP1, MISE, SOSS-C ENSG00000148153 INTS3 and NABP interacting protein 9 112683926-112718236 Predicted intracellular proteins Evidence at protein level HPA020382 Approved Supported Nucleoplasm Renal cancer:2.00e-8 (favourable), Stomach cancer:2.53e-4 (favourable), Breast cancer:7.08e-4 (unfavourable) Expressed in all Mixed thyroid gland: 17.5 Expressed in all +UGCG GCS ENSG00000148154 UDP-glucose ceramide glucosyltransferase 9 111896766-111935369 Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA024124 Approved Endometrial cancer:4.44e-5 (favourable), Cervical cancer:6.62e-4 (favourable) Expressed in all Expressed in all adrenal gland: 84.1 Expressed in all +ACTL7B Tact1 ENSG00000148156 Actin like 7B 9 108854589-108856967 Predicted intracellular proteins Evidence at protein level HPA021803, HPA024664 Enhanced Not detected Tissue enriched 589 testis: 58.9 all non-specific tissues: 0.0 Not detected +SNX30 ATG24A ENSG00000148158 Sorting nexin family member 30 9 112750838-112881671 Predicted intracellular proteins Evidence at protein level HPA019346 Uncertain Approved Nucleus
Nucleoli
Cytosol Renal cancer:1.01e-7 (favourable) Expressed in all Mixed lung: 32.2 Expressed in all +STOM BND7, EPB7, EPB72 ENSG00000148175 Stomatin 9 121338988-121370304 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA010961, HPA011419 Approved Approved Golgi apparatus
Vesicles
Plasma membrane
Cytosol Expressed in all Expressed in all adipose tissue: 463.6 Cell line enhanced ASC diff: 468.5;hTCEpi: 411.2 +GSN DKFZp313L0718 ENSG00000148180 Gelsolin 9 121207794-121332843 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010823, CAB016728, CAB036009, HPA054026 Supported Supported Actin filaments Urothelial cancer:1.79e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 1354.2 Cell line enhanced ASC diff: 964.0;HaCaT: 513.8 +MRRF RRF ENSG00000148187 Mitochondrial ribosome recycling factor 9 122264603-122331343 Predicted intracellular proteins Evidence at protein level HPA047177, HPA049987 Enhanced Approved Microtubules
Cytokinetic bridge Renal cancer:2.14e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 34.6 Expressed in all +NR6A1 CT150, GCNF, GCNF1, RTR ENSG00000148200 Nuclear receptor subfamily 6 group A member 1 9 124517275-124771310 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031461, HPA045145 Supported Nucleus Tissue enriched Tissue enriched 8 testis: 42.7 thyroid gland: 5.1 Cell line enhanced BEWO: 107.1;K-562: 31.0;NTERA-2: 39.7 +CRB2 FLJ16786, FLJ38464 ENSG00000148204 Crumbs 2, cell polarity complex component 9 123356170-123380324 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA043674 Supported Group enriched Tissue enhanced cerebral cortex: 9.4 kidney: 2.0 Cell line enriched 7 AF22: 32.2 +OR5C1 hRPK-465_F_21, OR5C2P, OR9-F ENSG00000148215 Olfactory receptor family 5 subfamily C member 1 9 122788933-122789895 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ALAD ALADH, PBGS ENSG00000148218 Aminolevulinate dehydratase 9 113386317-113401333 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021023, HPA022124 Enhanced Colorectal cancer:7.33e-5 (unfavourable), Liver cancer:8.80e-5 (favourable), Renal cancer:1.65e-4 (favourable), Endometrial cancer:5.64e-4 (favourable) Expressed in all Expressed in all adrenal gland: 147.1 Expressed in all +ASTN2 KIAA0634 ENSG00000148219 Astrotactin 2 9 116425225-117415070 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027035 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:6.66e-16 (favourable) Expressed in all Expressed in all prostate: 40.5 Cell line enhanced SH-SY5Y: 39.4 +WDR31 FLJ35921 ENSG00000148225 WD repeat domain 31 9 113313222-113340298 Predicted intracellular proteins Evidence at transcript level HPA019340, HPA019347 Approved Approved Nuclear bodies
Cytosol Renal cancer:1.90e-9 (favourable), Endometrial cancer:1.85e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 16.3 testis: 9.2 Mixed +POLE3 CHARAC17, CHRAC17, p17, Ybl1 ENSG00000148229 DNA polymerase epsilon 3, accessory subunit 9 113407235-113410672 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA047945 Uncertain Approved Nucleus
Nucleoli Liver cancer:8.35e-4 (unfavourable) Expressed in all Expressed in all testis: 76.4 Expressed in all +SURF4 ERV29, FLJ22993, MGC102753 ENSG00000148248 Surfeit 4 9 133361449-133376166 Predicted membrane proteins, Transporters Evidence at protein level HPA064613 Approved Head and neck cancer:1.47e-5 (unfavourable), Breast cancer:5.85e-4 (unfavourable), Liver cancer:8.11e-4 (unfavourable) Expressed in all Expressed in all small intestine: 82.7 Expressed in all +GBGT1 A3GALNT, FS, MGC44848, UDP-GalNAc ENSG00000148288 Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 9 133152948-133163945 Predicted secreted proteins Evidence at protein level HPA051298 Approved Renal cancer:3.46e-5 (unfavourable), Colorectal cancer:6.22e-4 (unfavourable) Expressed in all Mixed placenta: 15.6 Cell line enhanced HEL: 53.1;HMC-1: 47.0 +SURF1 ENSG00000148290 SURF1, cytochrome c oxidase assembly factor 9 133351755-133356676 Disease related genes, Predicted membrane proteins Evidence at protein level CAB033946 Uncertain Renal cancer:6.92e-9 (favourable) Expressed in all Expressed in all epididymis: 46.8 Expressed in all +SURF2 ENSG00000148291 Surfeit 2 9 133356552-133361169 Predicted intracellular proteins Evidence at protein level HPA044340, HPA052213 Approved Enhanced Nucleus
Nucleoli Expressed in all Expressed in all testis: 39.1 Expressed in all +SURF6 FLJ30322, RRP14 ENSG00000148296 Surfeit 6 9 133328774-133336398 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023608, HPA074622 Approved Enhanced Nucleus
Nucleoli Renal cancer:7.31e-5 (favourable) Expressed in all Mixed ovary: 8.8 Expressed in all +MED22 Med24, SURF5 ENSG00000148297 Mediator complex subunit 22 9 133338323-133348131 Predicted intracellular proteins Evidence at protein level HPA020391, HPA063694 Uncertain Approved Nucleoplasm Renal cancer:3.76e-11 (favourable), Liver cancer:5.16e-6 (unfavourable), Pancreatic cancer:6.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 10.9 Expressed in all +REXO4 hPMC2, XPMC2H ENSG00000148300 REX4 homolog, 3'-5' exonuclease 9 133406059-133418096 Predicted intracellular proteins Evidence at protein level HPA047006 Uncertain Supported Nucleus
Nucleoli Liver cancer:4.76e-6 (unfavourable), Renal cancer:2.65e-4 (favourable) Expressed in all Expressed in all testis: 11.2 Expressed in all +RPL7A L7A, SURF3, TRUP ENSG00000148303 Ribosomal protein L7a 9 133348214-133351426 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046794 Approved Nucleoli
Vesicles Ovarian cancer:3.60e-5 (unfavourable), Liver cancer:8.99e-4 (unfavourable) Expressed in all Expressed in all ovary: 2618.0 Expressed in all +GTF3C5 TFiiiC2-63, TFIIIC63, TFIIICepsilon ENSG00000148308 General transcription factor IIIC subunit 5 9 133030675-133058503 Predicted intracellular proteins Evidence at protein level HPA067063, HPA069805 Supported Enhanced Nucleoplasm Expressed in all Expressed in all ovary: 48.2 Expressed in all +ASB6 ENSG00000148331 Ankyrin repeat and SOCS box containing 6 9 129634604-129642169 Predicted intracellular proteins Evidence at protein level HPA004341 Approved Colorectal cancer:1.06e-5 (unfavourable), Liver cancer:2.40e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 22.7 Expressed in all +PTGES2 C9orf15, FLJ14038 ENSG00000148334 Prostaglandin E synthase 2 9 128120693-128128462 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020631, HPA020733 Approved Approved Mitochondria Renal cancer:5.83e-7 (favourable) Expressed in all Expressed in all skeletal muscle: 35.1 Expressed in all +NTMT1 AD-003, C9orf32, HOMT1A, METTL11A, NRMT, NRMT1 ENSG00000148335 N-terminal Xaa-Pro-Lys N-methyltransferase 1 9 129608884-129636131 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020092, HPA058420 Uncertain Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 90.5 Expressed in all +CIZ1 LSFR1, ZNF356 ENSG00000148337 CDKN1A interacting zinc finger protein 1 9 128166064-128204383 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020380, HPA020387 Uncertain Enhanced Nucleoplasm Liver cancer:1.43e-4 (unfavourable) Expressed in all Expressed in all testis: 87.1 Expressed in all +SLC25A25 KIAA1896, MCSC, PCSCL ENSG00000148339 Solute carrier family 25 member 25 9 128068201-128109245 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020381 Uncertain Supported Vesicles
Mitochondria Renal cancer:4.65e-6 (favourable), Liver cancer:1.01e-4 (favourable) Expressed in all Expressed in all gallbladder: 62.9 Expressed in all +SH3GLB2 KIAA1848 ENSG00000148341 SH3 domain containing GRB2 like endophilin B2 9 129007036-129028303 Predicted intracellular proteins Evidence at protein level HPA021438, HPA024734 Approved Supported Nucleoplasm
Cytosol Cervical cancer:1.56e-6 (favourable), Renal cancer:2.32e-4 (favourable), Urothelial cancer:4.28e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 92.1 Expressed in all +MIGA2 C9orf54, FAM73B, FLJ00199, FLJ14596 ENSG00000148343 Mitoguardin 2 9 129036621-129072082 Predicted membrane proteins Evidence at protein level HPA041363 Approved Approved Cell Junctions
Cytosol Pancreatic cancer:3.04e-6 (favourable) Expressed in all Mixed small intestine: 15.5 Expressed in all +PTGES MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12 ENSG00000148344 Prostaglandin E synthase 9 129738331-129753047 Enzymes, Predicted membrane proteins Evidence at protein level HPA045064 Enhanced Supported Endoplasmic reticulum Pancreatic cancer:7.97e-5 (unfavourable), Colorectal cancer:2.32e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 82.9;seminal vesicle: 119.5 urinary bladder: 36.3 Cell line enhanced BEWO: 155.0;HaCaT: 189.3;U-2197: 372.3 +LCN2 24p3, NGAL ENSG00000148346 Lipocalin 2 9 128149071-128153455 Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002695, CAB016549, CAB016550 Enhanced Supported Endoplasmic reticulum Breast cancer:9.61e-4 (favourable) Mixed Tissue enhanced bone marrow: 1852.1;gallbladder: 3419.4 cervix, uterine: 1163.5 Group enriched 11 CAPAN-2: 3169.5;EFO-21: 1362.3 +LRSAM1 CMT2P, FLJ31641 ENSG00000148356 Leucine rich repeat and sterile alpha motif containing 1 9 127451486-127503501 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021403, HPA021844, CAB037304 Supported Approved Cytosol Pancreatic cancer:6.78e-6 (favourable), Renal cancer:5.72e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 20.8 Expressed in all +HMCN2 DKFZp434P0216, FLJ23816 ENSG00000148357 Hemicentin 2 9 130265882-130434123 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053903, HPA070647 Enhanced Approved Vesicles Mixed Mixed small intestine: 11.4 Cell line enhanced HaCaT: 6.9;RH-30: 17.3;SH-SY5Y: 4.4;U-87 MG: 4.0 +GPR107 FLJ20998, KIAA1624, LUSTR1, RP11-88G17 ENSG00000148358 G protein-coupled receptor 107 9 130053426-130140169 Predicted membrane proteins Evidence at protein level HPA031704 Supported Approved Nucleoplasm
Golgi apparatus Renal cancer:1.87e-5 (favourable), Breast cancer:3.56e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 55.3 Expressed in all +C9orf142 PAXX, XLS ENSG00000148362 Chromosome 9 open reading frame 142 9 136992418-136993984 Predicted intracellular proteins Evidence at protein level HPA045268 Uncertain Supported Nucleus Cervical cancer:2.06e-4 (favourable), Pancreatic cancer:6.71e-4 (favourable) Expressed in all Expressed in all spleen: 21.9 Expressed in all +IDI2 IPPI2 ENSG00000148377 Isopentenyl-diphosphate delta isomerase 2 10 1018907-1025859 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 41 skeletal muscle: 76.3 heart muscle: 1.8 Not detected +INPP5E CORS1, JBTS1, pharbin, PPI5PIV ENSG00000148384 Inositol polyphosphate-5-phosphatase E 9 136428619-136439823 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA065758 Approved Pancreatic cancer:1.82e-4 (favourable) Expressed in all Expressed in all testis: 15.9 Expressed in all +LCN9 ENSG00000148386 Lipocalin 9 9 135663322-135666422 Predicted secreted proteins Evidence at protein level HPA060941 Enhanced Not detected Tissue enhanced epididymis: 1.1 cerebral cortex: 0.6 Cell line enriched 19 BEWO: 16.2 +SEC16A KIAA0310, p250, Sec16L ENSG00000148396 SEC16 homolog A, endoplasmic reticulum export factor 9 136440096-136483759 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005684 Supported Supported Endoplasmic reticulum
Golgi apparatus Endometrial cancer:1.30e-6 (favourable), Renal cancer:4.47e-4 (favourable) Expressed in all Expressed in all prostate: 29.6 Expressed in all +DPH7 C9orf112, FLJ90634, RRT2, WDR85 ENSG00000148399 Diphthamide biosynthesis 7 9 137554904-137578935 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022911 Uncertain Approved Nuclear bodies Renal cancer:1.52e-5 (unfavourable), Urothelial cancer:3.23e-4 (favourable), Pancreatic cancer:6.52e-4 (favourable) Expressed in all Expressed in all fallopian tube: 18.1 Expressed in all +NOTCH1 TAN1 ENSG00000148400 Notch 1 9 136494444-136545862 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB008112, CAB022466, HPA067168 Supported Approved Nucleoplasm Renal cancer:5.45e-4 (unfavourable) Expressed in all Expressed in all skin: 24.0 Cell line enhanced MOLT-4: 77.4 +CACNA1B CACNL1A5, CACNN, Cav2.2 ENSG00000148408 Calcium voltage-gated channel subunit alpha1 B 9 137877789-138124624 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA044347 Uncertain Tissue enhanced Group enriched 8 adrenal gland: 3.7;cerebral cortex: 14.8;fallopian tube: 4.9;testis: 7.6 prostate: 0.9 Cell line enriched 6 SCLC-21H: 23.0 +NACC2 BEND9, BTBD14A, BTBD31, MGC23427 ENSG00000148411 NACC family member 2 9 136006537-136095285 Predicted intracellular proteins Evidence at protein level HPA047924, HPA052962 Approved Approved Nucleoli
Mitochondria Renal cancer:8.28e-5 (favourable), Stomach cancer:8.63e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 46.8 Mixed +PROSER2 C10orf47, MGC35403 ENSG00000148426 Proline and serine rich 2 10 11823339-11872277 Predicted intracellular proteins Evidence at protein level HPA041337 Uncertain Uncertain Plasma membrane
Cytosol Mixed Mixed placenta: 10.3 Cell line enhanced A-431: 74.3;CAPAN-2: 87.1 +USP6NL KIAA0019, RN-tre, RNTRE, TRE2NL, USP6NL-IT1 ENSG00000148429 USP6 N-terminal like 10 11453946-11611754 Predicted intracellular proteins Evidence at protein level HPA039196 Approved Head and neck cancer:8.06e-4 (favourable) Expressed in all Mixed testis: 45.0 Mixed +COMMD3 BUP, C10orf8 ENSG00000148444 COMM domain containing 3 10 22315974-22320308 Predicted intracellular proteins Evidence at protein level HPA036584 Approved Liver cancer:5.46e-7 (unfavourable) Expressed in all Expressed in all breast: 53.1 Expressed in all +MSRB2 CBS-1, CBS1, CGI-131, MSRB, PILB ENSG00000148450 Methionine sulfoxide reductase B2 10 23095506-23122013 Predicted secreted proteins Evidence at protein level HPA027933 Enhanced Expressed in all Mixed heart muscle: 28.1 Mixed +PDSS1 COQ1, TPRT, TPT ENSG00000148459 Decaprenyl diphosphate synthase subunit 1 10 26697659-26746798 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038032, HPA042741 Uncertain Approved Cytosol Liver cancer:1.25e-5 (unfavourable), Endometrial cancer:1.66e-4 (unfavourable) Expressed in all Mixed duodenum: 18.4 Expressed in all +FAM171A1 C10orf38, FLJ12884 ENSG00000148468 Family with sequence similarity 171 member A1 10 15211643-15371062 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA051345 Approved Approved Nucleoplasm
Plasma membrane Thyroid cancer:4.90e-6 (unfavourable), Renal cancer:2.71e-5 (favourable) Expressed in all Mixed cerebral cortex: 73.2 Cell line enhanced TIME: 95.9 +MINDY3 C10orf97, CARP, DERP5, FAM188A, FLJ13397, my042 ENSG00000148481 MINDY lysine 48 deubiquitinase 3 10 15778170-15860520 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038400, HPA038406 Uncertain Supported Nucleoplasm
Nuclear membrane Expressed in all Expressed in all testis: 39.2 Expressed in all +SLC39A12 FLJ30499 ENSG00000148482 Solute carrier family 39 member 12 10 17951839-18043292 Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Tissue enriched 28 cerebral cortex: 25.3 breast: 0.8 Not detected +TMEM236 bA162I21.2, bA16O1.2, FAM23A, FAM23B ENSG00000148483 Transmembrane protein 236 10 17752252-17800868 Predicted membrane proteins Evidence at protein level HPA045096 Enhanced Tissue enhanced Group enriched 9 colon: 14.4;duodenum: 22.1;rectum: 15.5;small intestine: 37.7 appendix: 2.3 Cell line enriched 9 MOLT-4: 8.4 +RSU1 FLJ31034, RSP-1 ENSG00000148484 Ras suppressor protein 1 10 16590611-16817528 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025927 Uncertain Approved Vesicles Renal cancer:9.32e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 58.8 Expressed in all +ST8SIA6 SIAT8F ENSG00000148488 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 10 17318383-17454330 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011635, HPA072708 Uncertain Uncertain Endoplasmic reticulum Tissue enhanced Tissue enhanced breast: 13.4;lung: 18.1 epididymis: 9.1 Cell line enriched 8 HMC-1: 442.5 +PARD3 ASIP, Baz, Bazooka, PAR3, PARD3A, PPP1R118 ENSG00000148498 Par-3 family cell polarity regulator 10 34109560-34815325 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030443 Approved Enhanced Cell Junctions Liver cancer:1.73e-5 (unfavourable), Urothelial cancer:4.41e-4 (unfavourable) Expressed in all Mixed skin: 68.7 Mixed +ANKRD30A NY-BR-1 ENSG00000148513 Ankyrin repeat domain 30A 10 37125788-37384111 Predicted intracellular proteins Evidence at protein level HPA071849 Tissue enriched Tissue enriched 15 breast: 49.8 testis: 3.3 Group enriched 34 A549: 2.4;U-266/70: 8.1 +ZEB1 AREB6, BZP, FECD6, NIL-2-A, PPCD3, TCF8, ZEB, Zfhep, Zfhx1a ENSG00000148516 Zinc finger E-box binding homeobox 1 10 31318495-31529814 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027524, CAB058686 Enhanced Supported Nucleoplasm Renal cancer:7.34e-6 (unfavourable) Expressed in all Mixed smooth muscle: 79.9 Cell line enhanced ASC TERT1: 102.9 +FAM13C FAM13C1 ENSG00000148541 Family with sequence similarity 13 member C 10 59246129-59363181 Predicted intracellular proteins Evidence at protein level HPA037888 Approved Approved Nucleoplasm
Cytosol Tissue enhanced Mixed cerebral cortex: 39.4 Cell line enhanced NTERA-2: 4.3;SCLC-21H: 10.0;SH-SY5Y: 5.3 +NRBF2 COPR1, COPR2, DKFZp564C1664, FLJ30395 ENSG00000148572 Nuclear receptor binding factor 2 10 63133247-63155031 Predicted intracellular proteins Evidence at protein level HPA021670, HPA059477 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:2.36e-4 (unfavourable) Expressed in all Expressed in all placenta: 30.7 Expressed in all +A1CF ACF, ACF64, ACF65, APOBEC1CF, ASP ENSG00000148584 APOBEC1 complementation factor 10 50799409-50885675 Predicted intracellular proteins Evidence at protein level HPA037779, HPA044079 Enhanced Supported Nucleoplasm Tissue enriched Tissue enhanced liver: 76.0;small intestine: 29.8 duodenum: 23.5 Group enriched 18 CACO-2: 19.3;Hep G2: 41.7 +CDHR1 CORD15, KIAA1775, PCDH21, RP65 ENSG00000148600 Cadherin related family member 1 10 84194635-84219621 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA036819 Supported Tissue enhanced Group enriched 5 rectum: 57.9;skin: 252.1 colon: 29.2 Cell line enhanced HAP1: 10.5;HEK 293: 4.8;HEL: 5.7;RPTEC TERT1: 12.5 +LRIT1 DKFZP434K091, FIGLER9, LRRC21, PAL ENSG00000148602 Leucine rich repeat, Ig-like and transmembrane domains 1 10 84231593-84241461 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 69 testis: 6.8 all non-specific tissues: 0.0 Not detected +RGR RP44 ENSG00000148604 Retinal G protein coupled receptor 10 84245053-84259960 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enriched 13 cerebral cortex: 16.1 testis: 1.2 Not detected +POLR3A hRPC155, RPC1, RPC155 ENSG00000148606 RNA polymerase III subunit A 10 77969251-78029545 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA037926 Uncertain Supported Nucleoplasm Liver cancer:3.64e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 17.9 Expressed in all +HERC4 DKFZP564G092, KIAA1593 ENSG00000148634 HECT and RLD domain containing E3 ubiquitin protein ligase 4 10 67921899-68075348 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045453, HPA070301 Uncertain Supported Nucleoli fibrillar center
Cytosol Renal cancer:3.86e-5 (unfavourable) Expressed in all Expressed in all testis: 32.5 Expressed in all +C10orf11 CDA017, OCA7 ENSG00000148655 Chromosome 10 open reading frame 11 10 75431453-76560167 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047446, HPA050419 Approved Supported Nucleus
Cytosol Mixed Mixed epididymis: 73.4 Cell line enhanced Hep G2: 31.4;NB-4: 42.2;SK-MEL-30: 71.9;THP-1: 33.2;U-937: 34.6 +CAMK2G CAMKG ENSG00000148660 Calcium/calmodulin dependent protein kinase II gamma 10 73812501-73874591 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040656, HPA051783, HPA051785, HPA053973 Approved Supported Plasma membrane
Cell Junctions
Cytosol Expressed in all Expressed in all cerebral cortex: 119.0 Expressed in all +ADIRF AFRO, APM2, C10orf116 ENSG00000148671 Adipogenesis regulatory factor 10 86968192-86983934 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026810 Approved Supported Nucleoplasm
Cytosol Not detected Tissue enhanced adipose tissue: 265.8 small intestine: 144.5 Cell line enhanced A-431: 92.8;HaCaT: 235.9;PC-3: 133.9;RT4: 150.3 +GLUD1 GDH, GLUD ENSG00000148672 Glutamate dehydrogenase 1 10 87050486-87094866 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA042492, HPA044839, HPA061369 Approved Supported Mitochondria Renal cancer:1.44e-6 (favourable), Pancreatic cancer:1.76e-5 (unfavourable), Glioma:5.08e-4 (favourable) Expressed in all Expressed in all liver: 457.9 Expressed in all +ANKRD1 ALRP, C-193, CARP, CVARP, MCARP ENSG00000148677 Ankyrin repeat domain 1 10 90912096-90921276 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038736 Enhanced Supported Nucleus
Nucleoli fibrillar center Head and neck cancer:1.95e-4 (unfavourable) Tissue enhanced Tissue enriched 108 heart muscle: 3714.2 lung: 34.4 Group enriched 6 CACO-2: 348.0;EFO-21: 1053.3;HUVEC TERT2: 325.0;LHCN-M2: 1166.6;TIME: 1606.3 +HTR7 5-HT7 ENSG00000148680 5-hydroxytryptamine receptor 7 10 90740823-90857698 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level CAB022708, HPA073617 Approved Supported Nuclear speckles
Plasma membrane
Cytosol Group enriched Group enriched 8 parathyroid gland: 44.8;testis: 16.1 urinary bladder: 3.8 Cell line enhanced hTERT-HME1: 25.8;LHCN-M2: 11.4;WM-115: 12.9 +RPP30 TSG15 ENSG00000148688 Ribonuclease P/MRP subunit p30 10 90871716-90908553 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037578 Enhanced Approved Nucleus
Nucleoli
Microtubule ends
Cytosol Renal cancer:1.01e-6 (unfavourable) Expressed in all Expressed in all testis: 50.5 Expressed in all +FRA10AC1 C10orf4 ENSG00000148690 FRA10A associated CGG repeat 1 10 93667883-93702572 Predicted intracellular proteins Evidence at protein level HPA039204 Approved Expressed in all Expressed in all cerebral cortex: 21.3 Expressed in all +ADD3 ADDL ENSG00000148700 Adducin 3 10 109996368-110135565 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB009797, HPA035696 Supported Supported Plasma membrane Expressed in all Expressed in all thyroid gland: 168.6 Cell line enhanced ASC diff: 215.0;ASC TERT1: 204.7 +HABP2 FSAP, HABP, HGFAL, PHBP ENSG00000148702 Hyaluronan binding protein 2 10 113550837-113589602 Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA019518 Approved Tissue enriched Group enriched 12 gallbladder: 55.8;liver: 225.6 stomach: 11.3 Cell line enriched 5 RPTEC TERT1: 38.3 +VAX1 ENSG00000148704 Ventral anterior homeobox 1 10 117128521-117138301 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028946 Uncertain Approved Nucleus
Nucleoli Not detected Tissue enhanced cerebral cortex: 1.4 testis: 0.4 Group enriched 8 A-431: 2.9;WM-115: 2.4 +DNAJB12 DJ10, FLJ20027 ENSG00000148719 DnaJ heat shock protein family (Hsp40) member B12 10 72332830-72355230 Predicted membrane proteins Evidence at protein level HPA010642 Approved Supported Endoplasmic reticulum Colorectal cancer:4.79e-4 (unfavourable), Head and neck cancer:8.17e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 48.0 Expressed in all +EIF4EBP2 ENSG00000148730 Eukaryotic translation initiation factor 4E binding protein 2 10 70404379-70428618 Predicted intracellular proteins Evidence at protein level CAB019415, HPA037410, HPA061665 Approved Approved Nucleoplasm
Mitochondria Renal cancer:6.69e-6 (favourable) Expressed in all Expressed in all adipose tissue: 74.3 Expressed in all +NPFFR1 GPR147, NPFF1R1, OT7T022 ENSG00000148734 Neuropeptide FF receptor 1 10 70247329-70283676 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA037521 Uncertain Tissue enhanced Tissue enhanced testis: 2.1 cerebral cortex,lymph node: 0.8 Cell line enhanced U-2 OS: 1.0 +PLEKHS1 bA211N11.2, C10orf81, FLJ23537 ENSG00000148735 Pleckstrin homology domain containing S1 10 113751454-113783429 Predicted intracellular proteins Evidence at protein level HPA037583 Supported Centrosome Urothelial cancer:1.03e-4 (favourable) Mixed Tissue enhanced cervix, uterine: 88.6 duodenum: 41.1 Cell line enhanced CAPAN-2: 7.3;RH-30: 3.8;RT4: 12.5;T-47d: 4.9 +TCF7L2 TCF-4, TCF4 ENSG00000148737 Transcription factor 7 like 2 10 112950250-113167678 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB013535, HPA038800 Supported Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all endometrium: 30.9 Mixed +MKI67 MIB-, PPP1R105 ENSG00000148773 Marker of proliferation Ki-67 10 128096659-128126385 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000058, HPA000451, HPA001164, CAB068198 Enhanced Enhanced Nucleus
Nucleoli
Nuclear bodies Renal cancer:0.00e+0 (unfavourable), Liver cancer:3.61e-6 (unfavourable), Pancreatic cancer:9.47e-5 (unfavourable) Expressed in all Tissue enhanced bone marrow: 28.8 lymph node: 17.9 Mixed +CYP17A1 CPT7, CYP17, P450C17, S17AH ENSG00000148795 Cytochrome P450 family 17 subfamily A member 1 10 102830531-102837533 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA048533 Enhanced Renal cancer:5.43e-7 (favourable) Tissue enriched Tissue enriched 25 adrenal gland: 3751.4 testis: 152.4 Cell line enhanced HMC-1: 2.6;SCLC-21H: 1.3 +INA NEF5, NF-66 ENSG00000148798 Internexin neuronal intermediate filament protein alpha 10 103277163-103290351 Predicted intracellular proteins Evidence at protein level CAB002059, HPA008057 Enhanced Supported Supported Nucleoplasm
Nuclear membrane
Intermediate filaments Tissue enhanced Tissue enriched 6 cerebral cortex: 89.0 adrenal gland: 16.0 Cell line enhanced NTERA-2: 53.4;SCLC-21H: 122.4;SH-SY5Y: 62.7;SiHa: 76.3 +FUOM C10orf125, FLJ26016, FucM, FucU ENSG00000148803 Fucose mutarotase 10 133355154-133358035 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039207 Uncertain Expressed in all Tissue enhanced liver: 74.9 duodenum: 50.9 Mixed +LRRC27 KIAA1674 ENSG00000148814 Leucine rich repeat containing 27 10 132332154-132379918 Predicted intracellular proteins Evidence at protein level HPA037595, HPA067395 Enhanced Approved Nucleus
Golgi apparatus Mixed Tissue enhanced testis: 100.8 fallopian tube: 21.1 Mixed +MTG1 GTPBP7 ENSG00000148824 Mitochondrial ribosome associated GTPase 1 10 133394094-133421307 Predicted intracellular proteins Evidence at protein level HPA037826, HPA037827 Approved Supported Mitochondria Renal cancer:6.79e-7 (unfavourable), Urothelial cancer:1.03e-5 (favourable), Pancreatic cancer:5.08e-4 (favourable) Expressed in all Expressed in all testis: 29.5 Expressed in all +NKX6-2 GTX, NKX6.1, NKX6B ENSG00000148826 NK6 homeobox 2 10 132783179-132786052 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enriched Group enriched 25 cerebral cortex: 15.7;stomach: 16.7 testis: 0.6 Not detected +PAOX PAO ENSG00000148832 Polyamine oxidase 10 133379234-133391694 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047782 Uncertain Nucleoplasm
Centrosome Head and neck cancer:1.38e-5 (favourable), Cervical cancer:6.07e-5 (favourable), Renal cancer:9.49e-4 (favourable) Expressed in all Tissue enhanced testis: 7.6 cerebral cortex: 3.2 Cell line enhanced A-431: 5.2;U-266/70: 12.5 +GSTO1 GSTTLp28, P28 ENSG00000148834 Glutathione S-transferase omega 1 10 104235356-104267459 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037603, HPA037604 Enhanced Renal cancer:2.11e-4 (unfavourable), Breast cancer:6.95e-4 (favourable), Head and neck cancer:8.83e-4 (unfavourable) Expressed in all Expressed in all liver: 266.3 Expressed in all +TAF5 TAF2D, TAFII100 ENSG00000148835 TATA-box binding protein associated factor 5 10 103367967-103389065 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006195, HPA006474 Supported Supported Nucleoplasm Renal cancer:1.36e-9 (unfavourable), Stomach cancer:7.39e-5 (favourable) Expressed in all Tissue enhanced testis: 20.7 lymph node,placenta: 5.1 Expressed in all +PPRC1 KIAA0595, MGC74642, PRC ENSG00000148840 Peroxisome proliferator-activated receptor gamma, coactivator-related 1 10 102132994-102150331 Predicted intracellular proteins Evidence at protein level HPA038511, HPA057571 Approved Enhanced Nucleoplasm Renal cancer:6.71e-7 (unfavourable) Expressed in all Expressed in all smooth muscle: 20.8 Expressed in all +ITPRIP bA127L20.2, DANGER, KIAA1754 ENSG00000148841 Inositol 1,4,5-trisphosphate receptor interacting protein 10 104309698-104338404 Predicted membrane proteins Evidence at protein level HPA043626 Uncertain Vesicles Lung cancer:3.59e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 135.2 Mixed +CNNM2 ACDP2 ENSG00000148842 Cyclin and CBS domain divalent metal cation transport mediator 2 10 102918293-103090221 Disease related genes, Predicted membrane proteins Evidence at protein level HPA059954, HPA071631 Enhanced Vesicles Renal cancer:2.39e-8 (favourable) Expressed in all Tissue enhanced parathyroid gland: 33.6 placenta: 12.4 Expressed in all +PDCD11 ALG-4, KIAA0185, RRP5 ENSG00000148843 Programmed cell death 11 10 103396648-103446292 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017924, CAB026472 Approved Supported Nucleoli
Vesicles Liver cancer:2.79e-4 (unfavourable) Expressed in all Expressed in all testis: 27.9 Expressed in all +ADAM12 MCMPMltna, MLTN ENSG00000148848 ADAM metallopeptidase domain 12 10 126012381-126388455 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA030866, HPA030867, HPA030868 Enhanced Supported Plasma membrane Renal cancer:2.39e-14 (unfavourable) Mixed Tissue enriched 8 placenta: 237.2 cervix, uterine: 29.7 Cell line enhanced fHDF/TERT166: 119.5;hTEC/SVTERT24-B: 94.3;U-2197: 86.6;U-251 MG: 71.0 +RGS10 ENSG00000148908 Regulator of G-protein signaling 10 10 119499828-119542708 Predicted intracellular proteins Evidence at protein level CAB004559, HPA021305, HPA058485 Enhanced Supported Supported Nucleus
Plasma membrane Renal cancer:4.20e-10 (unfavourable), Endometrial cancer:6.32e-4 (favourable), Cervical cancer:6.81e-4 (favourable) Expressed in all Expressed in all lymph node: 137.6 Cell line enhanced HMC-1: 456.7 +BTBD10 GMRP-1, GMRP1, MGC13007 ENSG00000148925 BTB domain containing 10 11 13388001-13463297 Predicted intracellular proteins Evidence at protein level HPA046777 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:1.37e-4 (unfavourable) Expressed in all Expressed in all testis: 67.8 Expressed in all +ADM AM ENSG00000148926 Adrenomedullin 11 10304680-10307397 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016075 Approved Renal cancer:6.33e-4 (unfavourable), Liver cancer:7.56e-4 (unfavourable) Expressed in all Expressed in all placenta: 158.5 Cell line enhanced ASC diff: 519.0;U-138 MG: 397.2 +GAS2 ENSG00000148935 Growth arrest specific 2 11 22625642-22813055 Predicted intracellular proteins Evidence at protein level HPA058904 Enhanced Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Renal cancer:6.13e-4 (favourable) Tissue enhanced Tissue enhanced liver: 20.4 kidney: 5.5 Group enriched 11 Hep G2: 29.5;Karpas-707: 61.6;SCLC-21H: 29.3;U-266/84: 21.3 +SLC5A12 MGC52019, SMCT2 ENSG00000148942 Solute carrier family 5 member 12 11 26667019-26723427 Predicted membrane proteins, Transporters Evidence at protein level HPA060904 Enhanced Tissue enriched Tissue enhanced epididymis: 58.2;kidney: 173.7 small intestine: 33.4 Cell line enhanced Karpas-707: 1.6;NTERA-2: 1.7;T-47d: 1.1 +LIN7C FLJ11215, LIN-7-C, LIN-7C, Lin7c, MALS-3, VELI3 ENSG00000148943 Lin-7 homolog C, crumbs cell polarity complex component 11 27494576-27506773 Predicted intracellular proteins Evidence at protein level HPA051118 Approved Renal cancer:1.09e-4 (favourable) Expressed in all Expressed in all thyroid gland: 24.3 Expressed in all +LRRC4C KIAA1580, NGL-1 ENSG00000148948 Leucine rich repeat containing 4C 11 40114203-41459773 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051335, HPA054800 Approved Approved Cytosol Tissue enhanced Tissue enriched 7 cerebral cortex: 34.4 cervix, uterine: 4.7 Group enriched 9 AF22: 18.9;U-2 OS: 21.7 +IMMP1L FLJ25059, IMMP1 ENSG00000148950 Inner mitochondrial membrane peptidase subunit 1 11 31432401-31509645 Enzymes, Predicted intracellular proteins Evidence at protein level HPA058308 Approved Pancreatic cancer:6.72e-4 (favourable), Liver cancer:7.97e-4 (unfavourable) Expressed in all Expressed in all epididymis: 39.2 Expressed in all +SAA4 C-SAA, CSAA ENSG00000148965 Serum amyloid A4, constitutive 11 18231349-18236893 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB026061, HPA060139 Supported Tissue enriched Tissue enriched 42 liver: 776.2 cervix, uterine: 18.6 Cell line enriched 14 Hep G2: 15.6 +PGAP2 CWH43-N, FRAG1, MRT21 ENSG00000148985 Post-GPI attachment to proteins 2 11 3797724-3826371 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA063099 Approved Approved Microtubules Liver cancer:7.49e-4 (unfavourable) Expressed in all Expressed in all epididymis: 263.3 Expressed in all +TUT1 FLJ21850, FLJ22267, FLJ22347, PAPD2, RBM21, TUTase ENSG00000149016 Terminal uridylyl transferase 1, U6 snRNA-specific 11 62575045-62592177 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069055, HPA071838 Supported Nucleus
Cytosol Colorectal cancer:9.51e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 17.8 Expressed in all +SCGB1A1 CC10, CC16, CCSP, UGB ENSG00000149021 Secretoglobin family 1A member 1 11 62405103-62423195 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025686, HPA031828 Supported Tissue enriched Tissue enriched 9 lung: 4742.5 fallopian tube: 521.2 Cell line enriched 70 HaCaT: 1741.2 +SYT8 DKFZp434K0322 ENSG00000149043 Synaptotagmin 8 11 1828307-1837521 Predicted membrane proteins Evidence at transcript level HPA052700 Uncertain Approved Nucleoplasm
Cell Junctions Tissue enhanced Group enriched 5 gallbladder: 26.5;skin: 80.2;urinary bladder: 24.5 seminal vesicle: 8.6 Group enriched 6 CAPAN-2: 56.5;hTCEpi: 72.7;T-47d: 25.8 +ZNF214 ENSG00000149050 Zinc finger protein 214 11 6999318-7020368 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055391 Uncertain Mixed Mixed fallopian tube: 6.9 Mixed +ZNF215 ZKSCAN11, ZSCAN43 ENSG00000149054 Zinc finger protein 215 11 6926404-7001004 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047243, HPA051010 Enhanced Approved Nucleoplasm
Vesicles Mixed Mixed lymph node: 4.5 Cell line enhanced U-698: 14.5 +HSD17B12 KAR, SDR12C1 ENSG00000149084 Hydroxysteroid 17-beta dehydrogenase 12 11 43680558-43856617 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016427 Approved Renal cancer:2.10e-8 (favourable), Liver cancer:2.76e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 196.5 Expressed in all +APIP APIP2, CGI-29, Mmrp19 ENSG00000149089 APAF1 interacting protein 11 34853094-34916499 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021188, HPA024131 Approved Approved Nucleoplasm
Cytosol Liver cancer:1.99e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 33.2 Expressed in all +PAMR1 DKFZP586H2123, RAMP ENSG00000149090 Peptidase domain containing associated with muscle regeneration 1 11 35431823-35530300 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:5.08e-5 (unfavourable), Stomach cancer:6.29e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 87.0;endometrium: 92.2 placenta: 76.1 Cell line enhanced ASC TERT1: 233.7;BJ hTERT+: 274.9;HSkMC: 84.2;U-87 MG: 78.6 +DGKZ DAGK5, DAGK6, DGK-ZETA, hDGKzeta ENSG00000149091 Diacylglycerol kinase zeta 11 46332905-46380554 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051336 Supported Supported Nuclear speckles Renal cancer:4.74e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 132.6 Expressed in all +EIF3M eIF3m, FLJ29030, GA17, hfl-B5, PCID1, TANGO7 ENSG00000149100 Eukaryotic translation initiation factor 3 subunit M 11 32583798-32606262 Predicted intracellular proteins Evidence at protein level HPA031063 Approved Supported Cytosol Liver cancer:1.28e-9 (unfavourable) Expressed in all Expressed in all fallopian tube: 235.1 Expressed in all +TNKS1BP1 FLJ45975, KIAA1741, TAB182 ENSG00000149115 Tankyrase 1 binding protein 1 11 57299638-57324952 Predicted intracellular proteins Evidence at protein level HPA037929, HPA037930 Enhanced Renal cancer:2.11e-8 (unfavourable) Expressed in all Expressed in all skin: 79.1 Expressed in all +GLYAT ACGNAT, GAT ENSG00000149124 Glycine-N-acyltransferase 11 58640426-58731974 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040251, HPA044094 Enhanced Renal cancer:1.31e-6 (favourable) Group enriched Group enriched 10 kidney: 584.9;liver: 355.3 adipose tissue: 47.4 Mixed +SERPING1 C1-INH, C1IN, C1NH, HAE1, HAE2 ENSG00000149131 Serpin family G member 1 11 57597387-57614853 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026161, HPA048738 Supported Renal cancer:1.55e-4 (unfavourable), Ovarian cancer:8.03e-4 (favourable), Colorectal cancer:9.96e-4 (unfavourable) Expressed in all Expressed in all liver: 1365.0 Group enriched 5 ASC diff: 881.8;ASC TERT1: 462.5;HSkMC: 802.1 +OR5F1 OR11-10 ENSG00000149133 Olfactory receptor family 5 subfamily F member 1 11 55993681-55994625 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA059360 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +SSRP1 FACT80 ENSG00000149136 Structure specific recognition protein 1 11 57325985-57335877 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002697 Approved Approved Nucleus
Cytosol Liver cancer:4.03e-7 (unfavourable), Pancreatic cancer:1.40e-4 (unfavourable), Renal cancer:5.63e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 124.9 Expressed in all +SLC43A1 PB39, POV1, R00504 ENSG00000149150 Solute carrier family 43 member 1 11 57484534-57515786 Predicted membrane proteins, Transporters Evidence at protein level HPA018813, HPA018826 Enhanced Approved Golgi apparatus
Vesicles
Plasma membrane Renal cancer:2.97e-5 (unfavourable), Endometrial cancer:3.19e-4 (favourable), Thyroid cancer:5.27e-4 (unfavourable) Expressed in all Expressed in all liver: 50.0 Mixed +PTPRJ CD148, DEP1, HPTPeta ENSG00000149177 Protein tyrosine phosphatase, receptor type J 11 47980558-48170841 CD markers, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA006026 Approved Renal cancer:1.13e-5 (favourable) Expressed in all Mixed parathyroid gland: 38.6 Mixed +C11orf49 FLJ22210, MGC4707 ENSG00000149179 Chromosome 11 open reading frame 49 11 46936689-47164385 Predicted intracellular proteins Evidence at protein level HPA040051, HPA040280 Uncertain Approved Nuclear speckles Liver cancer:2.18e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 57.2 Expressed in all +ARFGAP2 FLJ14576, IRZ, Zfp289, ZNF289 ENSG00000149182 ADP ribosylation factor GTPase activating protein 2 11 47164299-47177125 Predicted intracellular proteins Evidence at protein level HPA016649, HPA018152 Enhanced Supported Golgi apparatus Renal cancer:7.65e-7 (favourable) Expressed in all Expressed in all skin: 90.1 Expressed in all +CELF1 BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, hNab50, NAB50, NAPOR ENSG00000149187 CUGBP Elav-like family member 1 11 47465944-47565569 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016114, HPA044597, CAB069989 Supported Enhanced Nucleoplasm Liver cancer:7.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 133.1 Expressed in all +HIKESHI C11orf73, HSPC138, HSPC179, OPI10 ENSG00000149196 Hikeshi, heat shock protein nuclear import factor 11 86302211-86345931 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035063, HPA035064 Approved Renal cancer:4.01e-12 (unfavourable), Liver cancer:8.81e-4 (unfavourable) Expressed in all Expressed in all endometrium: 46.6 Expressed in all +CCDC81 FLJ16339, FLJ23514 ENSG00000149201 Coiled-coil domain containing 81 11 86374736-86423109 Predicted intracellular proteins Evidence at protein level HPA040745, HPA040827 Uncertain Uncertain Plasma membrane Tissue enhanced Group enriched 10 fallopian tube: 46.1;testis: 11.0 endometrium: 2.7 Cell line enhanced BJ: 2.9;HBF TERT88: 1.8 +SESN3 MGC29667, SEST3 ENSG00000149212 Sestrin 3 11 95165513-95232541 Predicted intracellular proteins Evidence at protein level HPA037935 Approved Nucleoplasm
Cytosol Expressed in all Tissue enhanced testis: 104.8 parathyroid gland: 54.5 Cell line enhanced AF22: 27.8;ASC diff: 32.0;ASC TERT1: 35.5 +ENDOD1 KIAA0830 ENSG00000149218 Endonuclease domain containing 1 11 95089810-95132645 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA008932, HPA010517 Enhanced Approved Nuclear membrane Renal cancer:6.64e-7 (favourable), Urothelial cancer:3.27e-4 (unfavourable), Pancreatic cancer:8.86e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 99.6 Cell line enhanced ASC diff: 132.3 +CCDC82 FLJ23518 ENSG00000149231 Coiled-coil domain containing 82 11 96352769-96389923 Predicted intracellular proteins Evidence at protein level HPA038704 Uncertain Approved Nucleus
Cytosol Expressed in all Expressed in all testis: 55.5 Mixed +KLHL35 FLJ33790 ENSG00000149243 Kelch like family member 35 11 75422394-75430629 Predicted intracellular proteins Evidence at protein level HPA039232, HPA039864 Uncertain Approved Nucleus
Nucleoli fibrillar center
Centrosome Cervical cancer:4.63e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 3.6;testis: 6.2 cervix, uterine: 1.1 Cell line enhanced CACO-2: 13.0;HMC-1: 8.9;PC-3: 8.3;SiHa: 19.5 +TENM4 KIAA1302, ODZ4, Ten-M4 ENSG00000149256 Teneurin transmembrane protein 4 11 78652831-79440948 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019521, HPA065961 Approved Mixed Tissue enhanced ovary: 20.8;parathyroid gland: 54.0 thyroid gland: 9.7 Cell line enhanced PC-3: 9.9;SH-SY5Y: 18.6 +SERPINH1 CBP1, CBP2, colligen, HSP47, SERPINH2 ENSG00000149257 Serpin family H member 1 11 75562056-75572783 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB004441, HPA029198 Supported Enhanced Endoplasmic reticulum Renal cancer:3.22e-15 (unfavourable), Head and neck cancer:1.85e-4 (unfavourable), Cervical cancer:2.10e-4 (unfavourable) Expressed in all Expressed in all placenta: 329.1 Mixed +CAPN5 ADNIV, HTRA3, nCL-3, VRNI ENSG00000149260 Calpain 5 11 77066932-77126155 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033237 Uncertain Endometrial cancer:2.16e-6 (unfavourable) Expressed in all Mixed colon: 61.0 Mixed +INTS4 INT4, MGC16733, MST093 ENSG00000149262 Integrator complex subunit 4 11 77878720-77994678 Predicted intracellular proteins Evidence at protein level HPA042378 Uncertain Approved Nucleoli Liver cancer:9.44e-6 (unfavourable), Thyroid cancer:9.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.8 Expressed in all +PAK1 ENSG00000149269 P21 (RAC1) activated kinase 1 11 77321707-77474635 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA003565, CAB005312 Enhanced Supported Enhanced Plasma membrane
Cytosol Glioma:9.48e-5 (unfavourable), Colorectal cancer:5.87e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 184.2 Mixed +RPS3 FLJ26283, FLJ27450, MGC87870, S3 ENSG00000149273 Ribosomal protein S3 11 75399486-75422280 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA063339 Uncertain Enhanced Endoplasmic reticulum
Cytosol Renal cancer:6.92e-6 (unfavourable) Expressed in all Expressed in all ovary: 3537.9 Expressed in all +ZC3H12C KIAA1726, MCPIP3 ENSG00000149289 Zinc finger CCCH-type containing 12C 11 110093361-110171841 Predicted intracellular proteins Evidence at protein level HPA038836, HPA038837 Approved Approved Nuclear membrane
Golgi apparatus Renal cancer:9.90e-6 (favourable) Expressed in all Mixed thyroid gland: 13.6 Mixed +TTC12 FLJ13859, FLJ20535, TPARM ENSG00000149292 Tetratricopeptide repeat domain 12 11 113314529-113383544 Predicted intracellular proteins Evidence at protein level HPA038542, HPA038543, HPA061364 Approved Approved Nucleoplasm Endometrial cancer:2.48e-5 (favourable), Renal cancer:5.95e-5 (favourable), Colorectal cancer:3.14e-4 (favourable) Expressed in all Expressed in all testis: 92.4 Cell line enhanced SiHa: 27.4 +NCAM1 CD56, NCAM ENSG00000149294 Neural cell adhesion molecule 1 11 112961247-113278436 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000142, CAB018071, HPA039835 Enhanced Enhanced Plasma membrane
Cytosol Pancreatic cancer:9.11e-6 (favourable), Renal cancer:8.20e-4 (unfavourable) Tissue enriched Tissue enhanced cerebral cortex: 334.9 heart muscle: 87.5 Cell line enhanced RH-30: 128.0;SCLC-21H: 126.2;U-138 MG: 71.8;WM-115: 77.9 +DRD2 ENSG00000149295 Dopamine receptor D2 11 113409615-113475691 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA015139, HPA015691 Supported Supported Mixed Tissue enhanced adrenal gland: 11.2 smooth muscle: 2.2 Cell line enriched 10 SCLC-21H: 104.3 +C11orf52 FLJ25219, MGC14839 ENSG00000149300 Chromosome 11 open reading frame 52 11 111918032-111926872 Predicted intracellular proteins Evidence at protein level HPA038387, HPA038388 Uncertain Enhanced Cell Junctions Not detected Mixed kidney: 44.9 Cell line enhanced CAPAN-2: 19.2;RPTEC TERT1: 20.1;T-47d: 70.7 +HTR3B 5-HT3B ENSG00000149305 5-hydroxytryptamine receptor 3B 11 113904677-113946565 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039559 Approved Not detected Tissue enhanced cerebral cortex: 2.7 testis: 1.1 Not detected +NPAT E14, p220 ENSG00000149308 Nuclear protein, coactivator of histone transcription 11 108157215-108222642 Predicted intracellular proteins Evidence at protein level HPA045908, HPA066370 Supported Nucleoplasm
Nuclear bodies Expressed in all Mixed lymph node: 17.5 Expressed in all +ATM ATA, ATC, ATD, ATDC, TEL1, TELO1 ENSG00000149311 ATM serine/threonine kinase 11 108222484-108369102 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000102, HPA067142 Supported Supported Nucleoplasm Expressed in all Expressed in all lymph node: 40.8 Expressed in all +AASDHPPT AASD-PPT, ACPS, CGI-80, LYS5 ENSG00000149313 Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 11 106075501-106098710 Predicted intracellular proteins Evidence at protein level HPA026687 Approved Renal cancer:4.27e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 81.9 Expressed in all +GLB1L2 ENSG00000149328 Galactosidase beta 1 like 2 11 134331874-134378341 Predicted secreted proteins Evidence at protein level HPA054808, HPA059955 Uncertain Supported Nucleus Mixed Tissue enhanced parathyroid gland: 53.2;prostate: 56.1 fallopian tube: 41.3 Cell line enhanced CAPAN-2: 43.7;HaCaT: 46.4;SCLC-21H: 41.1 +SLX4IP C20orf94, dJ1099D15.3 ENSG00000149346 SLX4 interacting protein 20 10435303-10636829 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046372 Approved Approved Cytosol Renal cancer:9.51e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 8.1 Mixed +LAMTOR1 C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1 ENSG00000149357 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 11 72085895-72103387 Predicted intracellular proteins Evidence at protein level HPA002997 Approved Supported Golgi apparatus
Vesicles
Plasma membrane Liver cancer:3.63e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 143.2 Expressed in all +P4HA3 C-P4Halpha(III) ENSG00000149380 Prolyl 4-hydroxylase subunit alpha 3 11 74235801-74311657 Enzymes, Predicted secreted proteins Evidence at protein level HPA007897 Approved Renal cancer:3.34e-9 (unfavourable), Urothelial cancer:7.83e-4 (unfavourable) Mixed Tissue enhanced smooth muscle: 14.5 gallbladder: 8.9 Cell line enhanced BJ: 16.3;HUVEC TERT2: 31.5;TIME: 22.1 +GRIK4 GluK4, GRIK, KA1 ENSG00000149403 Glutamate ionotropic receptor kainate type subunit 4 11 120511700-120988904 Predicted membrane proteins, Transporters Evidence at protein level HPA074453 Enhanced Tissue enriched Tissue enhanced cerebral cortex: 11.3 ovary,thyroid gland: 3.5 Group enriched 5 HDLM-2: 5.7;HEL: 16.7;T-47d: 4.4 +ST14 HAI, MT-SP1, PRSS14, SNC19, TMPRSS14 ENSG00000149418 Suppression of tumorigenicity 14 11 130159562-130210376 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA047014 Approved Nucleoplasm
Vesicles Renal cancer:5.03e-11 (favourable) Expressed in all Mixed small intestine: 149.0 Cell line enhanced CAPAN-2: 361.3;HaCaT: 255.1;RPMI-8226: 192.2;T-47d: 268.8 +HYOU1 Grp170, HSP12A, ORP150 ENSG00000149428 Hypoxia up-regulated 1 11 119044189-119057202 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA049296 Approved Renal cancer:5.10e-5 (unfavourable), Endometrial cancer:2.58e-4 (favourable), Thyroid cancer:5.00e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 111.7 Expressed in all +GGTLC1 dJ831C21.1, dJ831C21.2, GGTLA3, GGTLA4 ENSG00000149435 Gamma-glutamyltransferase light chain 1 20 23985050-23988779 Predicted intracellular proteins Evidence at protein level HPA045635, HPA047534 Uncertain Tissue enriched Group enriched 14 lung: 38.7;testis: 15.8 thyroid gland: 1.9 Not detected +ADAM33 C20orf153, dJ964F7.1, DKFZp434K0521 ENSG00000149451 ADAM metallopeptidase domain 33 20 3667965-3682246 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA067152, HPA071758 Approved Uncertain Nuclear speckles
Plasma membrane Mixed Mixed endometrium: 103.3 Cell line enhanced ASC diff: 55.2;ASC TERT1: 72.4;BJ: 31.3;BJ hTERT+: 51.1;fHDF/TERT166: 29.6;U-2197: 46.1 +SLC22A8 OAT3 ENSG00000149452 Solute carrier family 22 member 8 11 62989154-63015839 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA044174 Enhanced Tissue enhanced Tissue enriched 395 kidney: 339.8 cerebral cortex: 0.8 Not detected +KAT14 ATAC2, CRP2BP, CSRP2BP, dJ717M23.1, PRO1194 ENSG00000149474 Lysine acetyltransferase 14 20 18138118-18188387 Predicted intracellular proteins Evidence at protein level CAB034224, HPA068443 Uncertain Approved Vesicles Renal cancer:4.64e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 21.4 Expressed in all +TKFC DAK, DKFZP586B1621, NET45 ENSG00000149476 Triokinase and FMN cyclase 11 61333210-61353295 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039486, HPA048186 Enhanced Approved Nucleus
Cytosol Endometrial cancer:1.32e-5 (favourable), Renal cancer:8.38e-5 (favourable) Expressed in all Expressed in all duodenum: 194.2 Expressed in all +MTA2 MTA1-L1, MTA1L1 ENSG00000149480 Metastasis associated 1 family member 2 11 62593214-62601840 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005315, HPA006214, CAB017522 Enhanced Enhanced Nucleoplasm Liver cancer:4.82e-5 (unfavourable) Expressed in all Expressed in all skin: 88.3 Expressed in all +TMEM138 HSPC196, JBTS16 ENSG00000149483 Transmembrane protein 138 11 61362001-61369509 Disease related genes, Predicted membrane proteins Evidence at protein level HPA042373 Approved Approved Microtubules Renal cancer:4.12e-6 (unfavourable), Liver cancer:7.90e-4 (unfavourable) Expressed in all Expressed in all epididymis: 24.9 Expressed in all +FADS1 D5D, FADS6, FADSD5, LLCDL1, TU12 ENSG00000149485 Fatty acid desaturase 1 11 61799625-61829318 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042705 Approved Renal cancer:1.95e-9 (unfavourable), Urothelial cancer:1.33e-4 (unfavourable), Thyroid cancer:2.79e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 89.1 Expressed in all +TMC2 C20orf145, dJ686C3.3 ENSG00000149488 Transmembrane channel like 2 20 2536607-2641784 Predicted membrane proteins Evidence at transcript level HPA046350 Uncertain Not detected Not detected testis: 0.9 Not detected +ROM1 ROM, TSPAN23 ENSG00000149489 Retinal outer segment membrane protein 1 11 62611722-62615120 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028910 Supported Approved Plasma membrane
Cytosol Renal cancer:2.85e-6 (unfavourable), Lung cancer:2.20e-4 (favourable) Tissue enriched Tissue enhanced cerebral cortex: 25.4 ovary: 13.3 Mixed +EML3 ELP95, FLJ35827 ENSG00000149499 Echinoderm microtubule associated protein like 3 11 62602218-62612765 Predicted intracellular proteins Evidence at protein level Renal cancer:3.13e-8 (unfavourable) Expressed in all Expressed in all appendix: 37.6 Expressed in all +INCENP FLJ31633 ENSG00000149503 Inner centromere protein 11 62123973-62153163 Predicted intracellular proteins Evidence at protein level CAB013292, HPA051339, HPA070550 Enhanced Supported Nucleus
Nuclear bodies
Midbody Pancreatic cancer:5.76e-5 (unfavourable), Liver cancer:1.25e-4 (unfavourable), Lung cancer:8.58e-4 (unfavourable) Expressed in all Mixed lymph node: 12.7 Expressed in all +ZP1 ENSG00000149506 Zona pellucida glycoprotein 1 11 60867562-60875693 Disease related genes, Predicted membrane proteins Evidence at transcript level Mixed Not detected epididymis,prostate: 0.2 Group enriched 37 RPMI-8226: 8.4;SK-BR-3: 2.5 +OOSP2 FLJ36198, PLAC1L, TMEM122 ENSG00000149507 Oocyte secreted protein 2 11 60040275-60048044 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA050914 Enhanced Not detected Tissue enriched 487 testis: 48.6 all non-specific tissues: 0.0 Not detected +MS4A3 CD20L, HTM4 ENSG00000149516 Membrane spanning 4-domains A3 11 60056587-60071128 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA019210 Supported Not detected Tissue enriched 256 bone marrow: 305.3 skin,spleen: 1.1 Cell line enhanced HEL: 172.0;K-562: 132.6;NB-4: 69.9;THP-1: 214.5;U-937: 98.3 +PLCH2 KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1 ENSG00000149527 Phospholipase C eta 2 1 2425980-2505530 Enzymes, Predicted intracellular proteins Evidence at protein level HPA072705 Approved Mixed Tissue enhanced skin: 58.5 esophagus: 14.0 Cell line enhanced HBEC3-KT: 91.6;hTCEpi: 42.6;hTERT-HME1: 26.9 +CPSF7 FLJ12529 ENSG00000149532 Cleavage and polyadenylation specific factor 7 11 61402641-61430031 Predicted intracellular proteins Evidence at protein level HPA041094 Supported Supported Nucleoplasm
Cytosol Liver cancer:9.83e-4 (unfavourable) Expressed in all Expressed in all endometrium: 76.2 Expressed in all +MS4A2 APY, FCER1B, IGER, MS4A1 ENSG00000149534 Membrane spanning 4-domains A2 11 60088261-60098466 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA059967 Enhanced Mixed Tissue enhanced lung: 24.8 gallbladder: 18.4 Cell line enhanced HEL: 2.4;THP-1: 1.0 +B3GAT3 GlcAT-I ENSG00000149541 Beta-1,3-glucuronyltransferase 3 11 62615296-62622175 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051328 Approved Liver cancer:5.11e-6 (unfavourable), Glioma:5.96e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 36.9 Expressed in all +EI24 EPG4, PIG8, TP53I8 ENSG00000149547 EI24, autophagy associated transmembrane protein 11 125569216-125584687 Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA047165, HPA051029 Approved Supported Endoplasmic reticulum
Golgi apparatus
Cytosol Pancreatic cancer:9.28e-4 (unfavourable) Expressed in all Tissue enriched 9 parathyroid gland: 1120.1 liver: 125.1 Expressed in all +CCDC15 FLJ13215 ENSG00000149548 Coiled-coil domain containing 15 11 124954121-125041489 Predicted intracellular proteins Evidence at transcript level HPA040450, HPA041738 Uncertain Approved Plasma membrane
Cytosol Mixed Tissue enriched 5 testis: 18.9 breast: 3.5 Mixed +CHEK1 CHK1 ENSG00000149554 Checkpoint kinase 1 11 125625136-125676255 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044364 Approved Nucleoplasm
Vesicles Renal cancer:1.04e-8 (unfavourable), Pancreatic cancer:3.10e-6 (unfavourable), Liver cancer:3.70e-6 (unfavourable), Colorectal cancer:3.62e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 62.5;seminal vesicle: 52.6 testis: 22.1 Expressed in all +FEZ1 UNC-76 ENSG00000149557 Fasciculation and elongation protein zeta 1 11 125445745-125496317 Predicted intracellular proteins Evidence at protein level HPA038490 Supported Microtubules
Cytosol Renal cancer:2.16e-6 (unfavourable), Cervical cancer:9.06e-5 (unfavourable) Tissue enriched Tissue enriched 10 cerebral cortex: 410.9 urinary bladder: 41.3 Cell line enhanced AF22: 156.1;NTERA-2: 145.3;SCLC-21H: 181.1 +ESAM W117m ENSG00000149564 Endothelial cell adhesion molecule 11 124752583-124762290 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA051043, HPA056293 Uncertain Approved Microtubules Expressed in all Expressed in all placenta: 157.9 Group enriched 15 HEL: 198.2;HUVEC TERT2: 233.4;TIME: 115.5 +KIRREL3 KIAA1867, KIRRE, NEPH2 ENSG00000149571 Kin of IRRE like 3 (Drosophila) 11 126423359-127003460 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA053324, HPA056320 Enhanced Tissue enhanced Tissue enriched 11 cerebral cortex: 20.4 adrenal gland: 1.9 Cell line enhanced BJ: 21.4;BJ hTERT+: 12.0;fHDF/TERT166: 14.2;U-138 MG: 11.2;U-251 MG: 11.6 +MPZL2 EVA, EVA1 ENSG00000149573 Myelin protein zero like 2 11 118253403-118264536 Predicted membrane proteins Evidence at protein level HPA060740 Approved Approved Cell Junctions Pancreatic cancer:1.14e-4 (unfavourable), Thyroid cancer:1.62e-4 (favourable) Expressed in all Tissue enhanced esophagus: 209.1 urinary bladder: 118.1 Cell line enhanced CAPAN-2: 107.3;EFO-21: 123.8;HaCaT: 149.0;RT4: 257.4;TIME: 288.5 +SCN2B ENSG00000149575 Sodium voltage-gated channel beta subunit 2 11 118161951-118176673 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Mixed Group enriched 9 cerebral cortex: 34.7;heart muscle: 7.1 smooth muscle: 2.4 Cell line enhanced U-2197: 1.6 +SIDT2 CGI-40 ENSG00000149577 SID1 transmembrane family member 2 11 117178733-117197445 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA052352 Approved Renal cancer:4.18e-5 (unfavourable) Expressed in all Expressed in all prostate: 60.8 Expressed in all +TMEM25 FLJ14399 ENSG00000149582 Transmembrane protein 25 11 118531041-118547280 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012163, HPA051562 Approved Approved Golgi apparatus
Vesicles Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all duodenum: 47.0 Cell line enhanced T-47d: 41.7 +TAGLN DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10 ENSG00000149591 Transgelin 11 117199321-117204782 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001447, HPA019467 Enhanced Approved Microtubules
Mitochondria
Cytosol Renal cancer:2.12e-7 (unfavourable) Expressed in all Expressed in all smooth muscle: 11975.2 Expressed in all +JPH2 JP-2 ENSG00000149596 Junctophilin 2 20 44111695-44187578 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052646 Approved Mixed Tissue enhanced skeletal muscle: 72.1;smooth muscle: 56.0 seminal vesicle: 47.8 Cell line enhanced EFO-21: 21.6;fHDF/TERT166: 18.5;SiHa: 16.8 +DUSP15 bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY ENSG00000149599 Dual specificity phosphatase 15 20 31847637-31870747 Enzymes, Predicted intracellular proteins Evidence at protein level HPA076649 Enhanced Approved Plasma membrane
Cytosol Renal cancer:5.40e-7 (favourable) Mixed Tissue enhanced testis: 77.1 parathyroid gland: 16.1 Cell line enhanced REH: 14.6;SH-SY5Y: 4.6 +COMMD7 C20orf92, dJ1085F17.3 ENSG00000149600 COMM domain containing 7 20 32702691-32743997 Predicted intracellular proteins Evidence at protein level HPA054119 Supported Vesicles Liver cancer:1.46e-4 (unfavourable), Urothelial cancer:3.53e-4 (favourable) Expressed in all Expressed in all thyroid gland: 80.3 Expressed in all +C20orf144 bclt, dJ63M2.6 ENSG00000149609 Chromosome 20 open reading frame 144 20 33662284-33665619 Predicted intracellular proteins Evidence at protein level HPA019029 Enhanced Not detected Tissue enriched 435 testis: 43.4 all non-specific tissues: 0.0 Not detected +KIAA1755 RP5-1054A22.3 ENSG00000149633 KIAA1755 20 38210488-38260772 Predicted intracellular proteins Evidence at protein level HPA051064 Approved Approved Nucleoli
Golgi apparatus
Vesicles Tissue enhanced Mixed cerebral cortex: 33.6 Cell line enhanced AF22: 74.8;ASC TERT1: 11.9;WM-115: 19.1 +SPATA25 C20orf165, dJ337O18.8, TSG23 ENSG00000149634 Spermatogenesis associated 25 20 45886489-45887635 Predicted intracellular proteins Evidence at protein level HPA041386 Approved Golgi apparatus Mixed Mixed testis: 15.4 Mixed +OCSTAMP C20orf123, dJ257E24.3 ENSG00000149635 Osteoclast stimulatory transmembrane protein 20 46540946-46550574 Predicted membrane proteins, Transporters Evidence at transcript level HPA031116 Uncertain Not detected Not detected testis: 0.2 Cell line enhanced AF22: 1.1;HMC-1: 2.0;NB-4: 1.6;U-266/84: 1.7 +DSN1 C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13 ENSG00000149636 DSN1 homolog, MIS12 kinetochore complex component 20 36751791-36773818 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002813, HPA030627 Enhanced Supported Nucleus
Nucleoli fibrillar center
Nuclear bodies
Cytosol Renal cancer:1.54e-5 (unfavourable), Liver cancer:4.16e-5 (unfavourable), Cervical cancer:4.49e-4 (favourable) Expressed in all Mixed testis: 40.2 Expressed in all +SOGA1 C20orf117, dJ132F21.1, FLJ44670, KIAA0889, SOGA ENSG00000149639 Suppressor of glucose, autophagy associated 1 20 36777442-36863686 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043992 Approved Approved Nucleoli
Cytosol Ovarian cancer:8.28e-5 (unfavourable), Renal cancer:4.49e-4 (unfavourable) Expressed in all Mixed thyroid gland: 20.2 Mixed +CNBD2 C20orf152, CNMPD1, dJ954P9.1 ENSG00000149646 Cyclic nucleotide binding domain containing 2 20 35954564-36030700 Predicted intracellular proteins Evidence at protein level HPA043182 Uncertain Not detected Tissue enhanced testis: 38.0 epididymis: 15.3 Mixed +SPINT4 C20orf137, dJ601O1.1 ENSG00000149651 Serine peptidase inhibitor, Kunitz type 4 20 45722351-45725830 Predicted secreted proteins Evidence at protein level HPA046703 Enhanced Not detected Tissue enriched 1619 epididymis: 347.0 seminal vesicle: 0.2 Not detected +CDH22 C20orf25, dJ998H6.1 ENSG00000149654 Cadherin 22 20 46173733-46308498 Predicted membrane proteins Evidence at transcript level HPA012164 Uncertain Mixed Group enriched 6 adrenal gland: 2.0;cerebral cortex: 10.2;fallopian tube: 2.3;skin: 5.1 prostate,seminal vesicle,testis: 0.7 Cell line enriched 23 SCLC-21H: 3.7 +LSM14B bA11M20.3, C20orf40, FAM61B, FLJ25473, FT005, LSM13, RAP55B ENSG00000149657 LSM family member 14B 20 62122461-62135378 Predicted intracellular proteins Evidence at protein level HPA041274, HPA061189 Approved Supported Nucleoli fibrillar center
Vesicles Liver cancer:3.61e-5 (unfavourable) Expressed in all Expressed in all testis: 78.8 Expressed in all +YTHDF1 C20orf21, FLJ20391 ENSG00000149658 YTH N6-methyladenosine RNA binding protein 1 20 63195429-63216234 Predicted intracellular proteins Evidence at protein level Liver cancer:1.65e-5 (unfavourable), Breast cancer:7.96e-4 (unfavourable), Thyroid cancer:9.60e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 42.4 Expressed in all +CABLES2 C20orf150, dJ908M14.2, ik3-2 ENSG00000149679 Cdk5 and Abl enzyme substrate 2 20 62388632-62407285 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052138 Approved Nuclear bodies
Cell Junctions Renal cancer:1.24e-6 (unfavourable), Endometrial cancer:5.26e-5 (unfavourable) Expressed in all Tissue enriched 6 testis: 58.3 cerebral cortex: 9.0 Expressed in all +ORAOV1 TAOS1 ENSG00000149716 Oral cancer overexpressed 1 11 69653076-69675416 Predicted intracellular proteins Evidence at protein level HPA062696 Approved Nucleoplasm Renal cancer:1.51e-5 (unfavourable) Expressed in all Expressed in all epididymis: 21.9 Expressed in all +GPHA2 A2, GPA2, MGC126572, ZSIG51 ENSG00000149735 Glycoprotein hormone alpha 2 11 64934471-64935888 Predicted secreted proteins Evidence at protein level Tissue enriched Group enriched 6 gallbladder: 26.3;pancreas: 76.9 testis: 7.9 Cell line enriched 6 Hep G2: 14.4 +SLC22A9 FLJ23666, OAT4, OAT7, UST3 ENSG00000149742 Solute carrier family 22 member 9 11 63369789-63410294 Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Tissue enriched 30 liver: 22.8 skeletal muscle: 0.7 Not detected +TRPT1 MGC11134 ENSG00000149743 TRNA phosphotransferase 1 11 64223799-64226254 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038705, HPA038706 Uncertain Approved Mitochondria Expressed in all Expressed in all testis: 44.9 Expressed in all +NUDT22 MGC13045 ENSG00000149761 Nudix hydrolase 22 11 64225941-64230686 Predicted intracellular proteins Evidence at protein level HPA039334, HPA053464 Approved Enhanced Nucleoplasm Renal cancer:2.18e-6 (favourable) Expressed in all Expressed in all duodenum: 31.1 Expressed in all +FERMT3 KIND3, MGC10966, MIG-2, MIG2B, UNC112C, URP2 ENSG00000149781 Fermitin family member 3 11 64206678-64223886 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065231 Approved Vesicles Renal cancer:2.12e-5 (unfavourable), Endometrial cancer:9.89e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 114.2 lymph node: 101.2 Cell line enhanced HEL: 276.6;HMC-1: 277.8 +PLCB3 ENSG00000149782 Phospholipase C beta 3 11 64251523-64269150 Enzymes, Predicted intracellular proteins Evidence at protein level CAB009257, HPA039279, HPA043907 Enhanced Enhanced Nucleoplasm Renal cancer:4.31e-5 (unfavourable), Liver cancer:1.39e-4 (unfavourable) Expressed in all Expressed in all duodenum: 114.9 Expressed in all +MRPL49 C11orf4, L49mt, NOF, NOF1 ENSG00000149792 Mitochondrial ribosomal protein L49 11 65122183-65127371 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046778 Approved Renal cancer:4.22e-15 (favourable), Breast cancer:3.79e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 83.4 Expressed in all +CDC42EP2 BORG1, CEP2 ENSG00000149798 CDC42 effector protein 2 11 65314818-65322429 Predicted intracellular proteins Evidence at protein level HPA038562 Approved Supported Microtubules
Cytosol Liver cancer:2.89e-5 (unfavourable), Lung cancer:6.66e-4 (unfavourable) Expressed in all Mixed adipose tissue: 46.1 Cell line enhanced U-2197: 69.2 +FAU asr1, FLJ22986, Fub1, Fubi, MNSFbeta, RPS30, S30 ENSG00000149806 FAU, ubiquitin like and ribosomal protein S30 fusion 11 65120628-65122473 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA059015 Supported Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 1268.8 Expressed in all +TM7SF2 ANG1, DHCR14A, NET47 ENSG00000149809 Transmembrane 7 superfamily member 2 11 65111845-65116384 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030691, HPA072704 Approved Supported Endoplasmic reticulum
Vesicles Renal cancer:8.49e-8 (favourable) Expressed in all Expressed in all adrenal gland: 160.5 Cell line enhanced T-47d: 122.6 +VPS51 ANG2, ANG3, C11orf2, C11orf3, FFR ENSG00000149823 VPS51, GARP complex subunit 11 65089324-65111860 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039650, HPA061447 Uncertain Approved Nucleoli
Golgi apparatus
Vesicles Renal cancer:2.41e-9 (favourable) Expressed in all Expressed in all ovary: 101.9 Expressed in all +TBX6 ENSG00000149922 T-box 6 16 30085793-30091887 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062498 Approved Nucleus Mixed Mixed stomach: 4.4 Cell line enhanced RT4: 5.5;U-266/70: 5.4 +PPP4C PP4, PPX ENSG00000149923 Protein phosphatase 4 catalytic subunit 16 30075978-30085377 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043837 Enhanced Supported Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 78.0 Expressed in all +ALDOA ENSG00000149925 Aldolase, fructose-bisphosphate A 16 30053090-30070457 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004177, CAB006252 Enhanced Supported Cytosol Liver cancer:5.79e-5 (unfavourable), Lung cancer:7.32e-5 (unfavourable) Expressed in all Tissue enriched 7 skeletal muscle: 9377.0 esophagus: 1428.8 Expressed in all +FAM57B DKFZP434I2117 ENSG00000149926 Family with sequence similarity 57 member B 16 30024427-30052978 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030837 Uncertain Tissue enriched Group enriched 12 cerebral cortex: 18.6;testis: 77.0 skeletal muscle: 3.9 Cell line enhanced NTERA-2: 16.7;SCLC-21H: 105.0;SH-SY5Y: 35.9 +DOC2A ENSG00000149927 Double C2 domain alpha 16 30005509-30023270 Predicted intracellular proteins Evidence at protein level HPA065676 Uncertain Nucleus
Nucleoli
Cell Junctions Tissue enhanced Group enriched 9 cerebral cortex: 69.7;testis: 21.0 ovary: 5.2 Cell line enhanced BEWO: 12.9;SCLC-21H: 42.7;U-937: 14.1 +HIRIP3 ENSG00000149929 HIRA interacting protein 3 16 29992321-29996436 Predicted intracellular proteins Evidence at protein level HPA051897, HPA063205 Approved Enhanced Nucleus Cervical cancer:2.74e-5 (favourable) Expressed in all Expressed in all testis: 38.5 Expressed in all +TAOK2 KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2 ENSG00000149930 TAO kinase 2 16 29973641-29992261 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010650 Approved Supported Nucleus
Nucleoli
Cytosol Endometrial cancer:3.87e-5 (favourable), Colorectal cancer:2.51e-4 (unfavourable), Renal cancer:3.66e-4 (favourable), Pancreatic cancer:4.78e-4 (favourable) Expressed in all Expressed in all testis: 36.9 Expressed in all +TMEM219 ENSG00000149932 Transmembrane protein 219 16 29940885-29973052 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059185 Approved Endometrial cancer:5.79e-4 (favourable) Expressed in all Expressed in all fallopian tube: 198.4 Expressed in all +HMGA2 BABL, HMGIC, LIPO ENSG00000149948 High mobility group AT-hook 2 12 65824131-65966295 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017809, HPA039076 Approved Supported Nucleus
Nucleoli Urothelial cancer:2.86e-4 (unfavourable), Head and neck cancer:4.79e-4 (unfavourable) Mixed Tissue enhanced testis: 3.7 bone marrow: 2.9 Cell line enhanced AF22: 292.5 +MMP3 STMY, STMY1 ENSG00000149968 Matrix metallopeptidase 3 11 102835801-102843803 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007875 Uncertain Supported Vesicles Pancreatic cancer:4.09e-4 (unfavourable), Cervical cancer:9.73e-4 (unfavourable) Tissue enhanced Tissue enhanced appendix: 26.5;endometrium: 58.6 urinary bladder: 9.0 Group enriched 15 BJ: 1172.2;BJ hTERT+: 3041.4;fHDF/TERT166: 1276.8 +CNKSR2 CNK2, KIAA0902, KSR2 ENSG00000149970 Connector enhancer of kinase suppressor of Ras 2 X 21374418-21654695 Predicted intracellular proteins Evidence at protein level HPA001502 Approved Golgi apparatus
Plasma membrane Tissue enhanced Tissue enriched 9 cerebral cortex: 53.9 adrenal gland: 5.8 Cell line enhanced A549: 6.4;NTERA-2: 10.9;RH-30: 9.6 +CNTN5 hNB-2, NB-2 ENSG00000149972 Contactin 5 11 99020953-100358885 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039492, HPA041223 Approved Supported Cytosol Not detected Tissue enhanced cerebral cortex: 2.6;placenta: 3.4;thyroid gland: 3.0 fallopian tube: 1.8 Not detected +KLRF1 CLEC5C, NKp80 ENSG00000150045 Killer cell lectin like receptor F1 12 9827481-9845007 Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced spleen: 24.9 bone marrow: 7.2 Cell line enhanced BJ hTERT+: 1.2;HAP1: 1.4;U-937: 3.5 +CLEC1A CLEC1, MGC34328 ENSG00000150048 C-type lectin domain family 1 member A 12 10069554-10111627 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Mixed Tissue enriched 5 placenta: 71.1 smooth muscle: 12.9 Cell line enhanced BEWO: 20.5;HUVEC TERT2: 15.2;U-266/84: 8.0 +MKX C10orf48, IRXL1, MGC39616 ENSG00000150051 Mohawk homeobox 10 27672875-27746060 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA006927 Uncertain Approved Nucleoplasm
Nuclear speckles Mixed Tissue enhanced ovary: 13.6;prostate: 26.0 fallopian tube: 8.2 Cell line enhanced BJ: 43.3;BJ hTERT+: 23.7;BJ hTERT+ SV40 Large T+: 30.7;fHDF/TERT166: 114.3 +MPP7 FLJ32798 ENSG00000150054 Membrane palmitoylated protein 7 10 28050993-28334486 Predicted intracellular proteins Evidence at protein level HPA037597, HPA037598 Enhanced Supported Cell Junctions Renal cancer:2.79e-14 (favourable), Lung cancer:5.88e-4 (favourable) Mixed Expressed in all esophagus: 41.2 Cell line enhanced CACO-2: 37.3;T-47d: 83.8 +ITGB1 CD29, FNRB, GPIIA, MDF2, MSK12 ENSG00000150093 Integrin subunit beta 1 10 32900319-33005792 Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB003434, HPA059297, HPA069003 Enhanced Supported Endoplasmic reticulum
Plasma membrane
Focal adhesion sites Lung cancer:3.36e-6 (unfavourable), Cervical cancer:5.01e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 1069.5 Expressed in all +FXYD4 CHIF ENSG00000150201 FXYD domain containing ion transport regulator 4 10 43371642-43376335 Predicted membrane proteins Evidence at protein level HPA058421 Enhanced Group enriched Tissue enriched 26 kidney: 127.4 stomach: 4.8 Not detected +TRIM48 RNF101 ENSG00000150244 Tripartite motif containing 48 11 55262182-55271119 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Not detected skin: 0.3 Not detected +OR8K1 ENSG00000150261 Olfactory receptor family 8 subfamily K member 1 11 56346039-56346998 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA055233 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR5M9 ENSG00000150269 Olfactory receptor family 5 subfamily M member 9 11 56462469-56463401 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +PCDH15 CDHR15, DFNB23, USH1F ENSG00000150275 Protocadherin related 15 10 53802771-55627942 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA074437 Supported Tissue enriched Tissue enhanced adrenal gland: 25.0;cerebral cortex: 12.2 kidney: 8.1 Cell line enhanced U-2 OS: 1.1;U-266/70: 2.5 +CTF1 CT-1, CT1 ENSG00000150281 Cardiotrophin 1 16 30896607-30903560 Predicted intracellular proteins Evidence at protein level CAB025853 Uncertain Glioma:5.72e-5 (unfavourable), Lung cancer:9.87e-4 (favourable) Expressed in all Mixed parathyroid gland: 28.7 Mixed +CWC15 AD002, C11orf5, Cwf15, HSPC148 ENSG00000150316 CWC15 spliceosome associated protein homolog 11 94962622-94973612 Predicted intracellular proteins Evidence at protein level HPA039878 Supported Approved Nuclear speckles
Mitochondria Renal cancer:1.91e-5 (unfavourable), Thyroid cancer:7.17e-4 (favourable), Ovarian cancer:9.75e-4 (favourable) Expressed in all Expressed in all testis: 79.2 Expressed in all +FCGR1A CD64, CD64A ENSG00000150337 Fc fragment of IgG receptor Ia 1 149782671-149792518 CD markers, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Renal cancer:4.83e-8 (unfavourable) Tissue enhanced Tissue enhanced epididymis: 91.1 appendix: 48.9 Cell line enriched 5 THP-1: 113.9 +ARID5B FLJ21150, MRF2 ENSG00000150347 AT-rich interaction domain 5B 10 61901300-62096944 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015037 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Plasma membrane
Cytosol Expressed in all Expressed in all smooth muscle: 62.1 Cell line enhanced BJ hTERT+: 91.0 +KLHL1 FLJ30047, KIAA1490, MRP2 ENSG00000150361 Kelch like family member 1 13 69700594-70108493 Predicted intracellular proteins Evidence at transcript level HPA021196 Uncertain Tissue enriched Tissue enhanced cerebral cortex: 1.9 prostate: 0.5 Cell line enriched 8 HeLa: 1.6 +CDH8 ENSG00000150394 Cadherin 8 16 61647242-62037035 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014908 Approved Tissue enhanced Group enriched 8 cerebral cortex: 27.8;seminal vesicle: 6.9 ovary: 2.1 Cell line enhanced AF22: 6.9;fHDF/TERT166: 4.9;HaCaT: 12.6;LHCN-M2: 14.1 +DCUN1D2 C13orf17, FLJ10704, FLJ20092 ENSG00000150401 Defective in cullin neddylation 1 domain containing 2 13 113455819-113490952 Predicted intracellular proteins Evidence at protein level HPA039349 Uncertain Approved Plasma membrane
Cytosol Pancreatic cancer:5.65e-5 (favourable) Expressed in all Expressed in all heart muscle: 66.6 Expressed in all +TMCO3 C13orf11, FLJ20623 ENSG00000150403 Transmembrane and coiled-coil domains 3 13 113490995-113554590 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039561, HPA048126 Uncertain Approved Cytosol Liver cancer:1.14e-5 (unfavourable), Urothelial cancer:4.10e-4 (unfavourable), Cervical cancer:5.80e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 48.6 Expressed in all +TMEM218 ENSG00000150433 Transmembrane protein 218 11 125096545-125111763 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038489 Uncertain Approved Plasma membrane
Cytosol Liver cancer:1.93e-5 (unfavourable), Stomach cancer:5.50e-4 (favourable) Expressed in all Expressed in all fallopian tube: 21.9 Expressed in all +TIRAP Mal, wyatt ENSG00000150455 TIR domain containing adaptor protein 11 126283065-126298845 Predicted intracellular proteins Evidence at protein level HPA054431 Uncertain Approved Nucleoplasm
Cytokinetic bridge
Cytosol Endometrial cancer:1.24e-4 (favourable) Expressed in all Mixed parathyroid gland: 13.4 Mixed +EEF1AKMT1 N6AMT2 ENSG00000150456 Eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1 13 20728731-20773958 Predicted intracellular proteins Evidence at protein level HPA040417, HPA042543 Uncertain Approved Plasma membrane
Cytosol Endometrial cancer:1.82e-4 (favourable) Expressed in all Expressed in all endometrium,fallopian tube: 18.1 Mixed +LATS2 ENSG00000150457 Large tumor suppressor kinase 2 13 20973032-21061547 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039191, HPA049037 Approved Supported Microtubule organizing center
Cytosol Cervical cancer:3.26e-4 (unfavourable) Expressed in all Expressed in all testis: 25.8 Mixed +SAP18 2HOR0202, MGC27131, SAP18p ENSG00000150459 Sin3A associated protein 18 13 21140514-21149084 Predicted intracellular proteins, Transporters Evidence at protein level HPA011352, CAB012273 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all testis: 257.2 Expressed in all +ADGRL3 KIAA0768, LEC3, LPHN3 ENSG00000150471 Adhesion G protein-coupled receptor L3 4 61201258-62078335 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA015027, HPA015762, CAB022698 Uncertain Tissue enriched Tissue enhanced cerebral cortex: 42.0;parathyroid gland: 30.6 cervix, uterine: 8.5 Cell line enhanced AF22: 41.2;EFO-21: 10.2 +KIAA1328 ENSG00000150477 KIAA1328 18 36829106-37232172 Predicted intracellular proteins Evidence at protein level HPA040946 Approved Approved Nuclear speckles
Vesicles
Lipid droplets Mixed Expressed in all testis: 35.8 Expressed in all +FAM124A FLJ30707 ENSG00000150510 Family with sequence similarity 124 member A 13 51222334-51284241 Predicted intracellular proteins Evidence at protein level HPA048182 Uncertain Approved Nucleus
Cytosol Mixed Mixed cerebral cortex: 13.9 Group enriched 5 HAP1: 18.4;HUVEC TERT2: 8.8;NTERA-2: 34.8;SH-SY5Y: 14.1 +MIA2 FLJ22404, TALI ENSG00000150526 Melanoma inhibitory activity 2 14 39230231-39253639 Predicted secreted proteins Evidence at protein level HPA054066, HPA055459 Supported Supported Endoplasmic reticulum Not detected Tissue enhanced epididymis: 3.7 parathyroid gland: 2.5 Cell line enhanced CAPAN-2: 3.0 +CTAGE5 cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, MEA6, MGEA, MGEA11, MGEA6 ENSG00000150527 CTAGE family member 5, ER export factor 14 39265284-39388513 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000387, HPA000922 Uncertain Renal cancer:2.81e-4 (favourable) Mixed Expressed in all thyroid gland: 77.4 Expressed in all +HNMT ENSG00000150540 Histamine N-methyltransferase 2 137964020-138016364 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035480, HPA035481 Approved Pancreatic cancer:3.41e-4 (unfavourable), Urothelial cancer:4.68e-4 (favourable) Expressed in all Expressed in all liver: 124.0 Cell line enhanced Hep G2: 152.7;RT4: 91.6 +LYPD1 LYPDC1, MGC29643 ENSG00000150551 LY6/PLAUR domain containing 1 2 132644853-132671579 Predicted secreted proteins Evidence at transcript level Tissue enhanced Group enriched 17 cerebral cortex: 27.2;fallopian tube: 127.3 salivary gland: 4.5 Cell line enhanced hTEC/SVTERT24-B: 56.7;U-251 MG: 88.0;WM-115: 207.2 +LYPD6B CT116, LYPD7 ENSG00000150556 LY6/PLAUR domain containing 6B 2 149038107-149215262 Predicted secreted proteins, Transporters Evidence at transcript level HPA049239 Uncertain Mixed Tissue enhanced gallbladder: 58.6;skin: 56.5 testis: 42.4 Cell line enhanced fHDF/TERT166: 50.2;LHCN-M2: 85.2;RT4: 43.6 +PDCD4 H731 ENSG00000150593 Programmed cell death 4 10 110871795-110900006 Predicted intracellular proteins Evidence at protein level HPA001032, HPA027214, CAB037024 Supported Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 461.7 Expressed in all +ADRA2A ADRA2, ADRA2R, ADRAR ENSG00000150594 Adrenoceptor alpha 2A 10 111077163-111080907 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Endometrial cancer:8.06e-4 (favourable) Expressed in all Mixed cervix, uterine: 33.2 Cell line enhanced ASC diff: 7.4;ASC TERT1: 9.3;HEL: 18.7;HeLa: 7.4;HSkMC: 23.3 +GPM6A GPM6 ENSG00000150625 Glycoprotein M6A 4 175632934-176002664 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017338 Supported Tissue enriched Tissue enriched 36 cerebral cortex: 1104.1 lung: 30.7 Group enriched 9 AF22: 49.3;Daudi: 30.7;HAP1: 18.0;U-251 MG: 42.1 +WDR17 ENSG00000150627 WD repeat domain 17 4 176065834-176182818 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042766, HPA054501 Approved Approved Nuclear speckles Mixed Tissue enhanced cerebral cortex: 25.2;parathyroid gland: 19.3 thyroid gland: 11.0 Cell line enhanced AF22: 7.7;SCLC-21H: 10.5 +SPATA4 SPEF1B, TSARG2 ENSG00000150628 Spermatogenesis associated 4 4 176184638-176195671 Predicted intracellular proteins Evidence at protein level HPA019220 Enhanced Not detected Tissue enriched 18 testis: 243.1 fallopian tube: 13.5 Cell line enhanced U-87 MG: 2.4 +VEGFC VRP ENSG00000150630 Vascular endothelial growth factor C 4 176683538-176792727 Cancer-related genes, Disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters Evidence at protein level Lung cancer:7.88e-5 (unfavourable), Renal cancer:1.17e-4 (unfavourable) Expressed in all Tissue enhanced thyroid gland: 51.7 placenta: 30.7 Cell line enhanced BJ: 135.8;HBF TERT88: 122.6;hTEC/SVTERT24-B: 129.0;LHCN-M2: 120.0 +CCDC102B ACY1L, AN, C18orf14, FLJ23594, HsT1731 ENSG00000150636 Coiled-coil domain containing 102B 18 68715209-69055189 Predicted intracellular proteins Evidence at protein level HPA040623, HPA048194 Approved Approved Mitochondria
Cytosol Renal cancer:2.90e-6 (unfavourable) Mixed Tissue enhanced placenta: 41.0 gallbladder: 21.6 Cell line enhanced ASC TERT1: 10.0;BJ hTERT+: 23.3;fHDF/TERT166: 20.3;HSkMC: 11.2 +CD226 DNAM-1, DNAM1, PTA1, TLiSA1 ENSG00000150637 CD226 molecule 18 69831158-69961803 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015715, HPA050348 Supported Approved Midbody Not detected Tissue enriched 11 parathyroid gland: 318.5 spleen: 28.4 Group enriched 7 HEL: 89.9;HMC-1: 37.6 +CNDP1 CN1, CPGL2, HsT2308, MGC10825 ENSG00000150656 Carnosine dipeptidase 1 18 74534440-74587212 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008933 Enhanced Group enriched Group enriched 12 cerebral cortex: 101.7;liver: 23.0 duodenum: 5.1 Cell line enriched 68 U-266/84: 57.1 +FSIP1 FLJ35989 ENSG00000150667 Fibrous sheath interacting protein 1 15 39600031-39782830 Predicted intracellular proteins Evidence at protein level HPA041002 Uncertain Uncertain Nucleoplasm Tissue enriched Group enriched 7 colon: 11.2;rectum: 18.4;testis: 13.6 breast: 2.2 Mixed +DLG2 chapsyn-110, PPP1R58, PSD-93, PSD93 ENSG00000150672 Discs large MAGUK scaffold protein 2 11 83455012-85627922 Predicted intracellular proteins Evidence at protein level HPA021307, HPA023896, CAB072341 Enhanced Approved Vesicles
Plasma membrane Mixed Tissue enhanced cerebral cortex: 72.8 thyroid gland: 25.8 Cell line enhanced BEWO: 7.6;NTERA-2: 5.5;SCLC-21H: 6.4;SH-SY5Y: 8.7;T-47d: 19.2 +CCDC83 CT148, FLJ42119, MGC34732 ENSG00000150676 Coiled-coil domain containing 83 11 85855101-85920021 Predicted intracellular proteins Evidence at transcript level HPA039707, HPA039882 Uncertain Nucleus
Plasma membrane
Cytosol Not detected Tissue enriched 148 testis: 63.5 cerebral cortex,endometrium: 0.4 Cell line enriched 8 MCF7: 2.1 +RGS18 RGS13 ENSG00000150681 Regulator of G-protein signaling 18 1 192158457-192185815 Predicted intracellular proteins Evidence at protein level HPA028727, HPA045780 Uncertain Approved Golgi apparatus Mixed Tissue enhanced spleen: 35.0 appendix: 19.2 Group enriched 6 HEL: 53.8;HL-60: 36.8;NB-4: 27.4;U-937: 31.1 +PRSS23 SIG13, SPUVE ENSG00000150687 Protease, serine 23 11 86791059-86952910 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030591 Uncertain Head and neck cancer:2.12e-4 (unfavourable), Renal cancer:3.06e-4 (unfavourable), Pancreatic cancer:5.56e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 397.1 Cell line enhanced HUVEC TERT2: 503.9;TIME: 926.9 +MTMR12 3-PAP, 3PAP, FLJ20476, KIAA1682, PIP3AP ENSG00000150712 Myotubularin related protein 12 5 32226994-32313009 Predicted intracellular proteins Evidence at protein level HPA051333 Supported Renal cancer:1.29e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 42.6 Expressed in all +PPP1R1C Inhibitor-1-like ENSG00000150722 Protein phosphatase 1 regulatory inhibitor subunit 1C 2 181954241-182131398 Predicted intracellular proteins Evidence at protein level HPA055043 Approved Nucleus
Nucleoli
Golgi apparatus Mixed Tissue enriched 9 heart muscle: 14.1 prostate: 1.6 Not detected +C11orf53 MGC50104 ENSG00000150750 Chromosome 11 open reading frame 53 11 111245805-111286401 Predicted intracellular proteins Evidence at transcript level HPA056128 Uncertain Mixed Tissue enhanced testis: 4.7 gallbladder: 2.2 Not detected +CCT5 KIAA0098 ENSG00000150753 Chaperonin containing TCP1 subunit 5 5 10249921-10266412 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002238, HPA005958, CAB006271 Enhanced Supported Nucleoli
Cytosol Liver cancer:6.57e-11 (unfavourable), Renal cancer:8.23e-6 (unfavourable) Expressed in all Expressed in all testis: 190.8 Expressed in all +FAM173B JS-2 ENSG00000150756 Family with sequence similarity 173 member B 5 10226330-10249897 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA074513 Approved Nucleus
Vesicles Breast cancer:1.32e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 26.2 Expressed in all +DOCK1 ced5, DOCK180 ENSG00000150760 Dedicator of cytokinesis 1 10 126905409-127452517 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004378, HPA048692, HPA053277 Approved Enhanced Nucleus Expressed in all Mixed parathyroid gland: 65.9 Mixed +DIXDC1 Dixin, KIAA1735 ENSG00000150764 DIX domain containing 1 11 111927144-112022584 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039658 Supported Cytosol Urothelial cancer:4.19e-5 (unfavourable), Renal cancer:6.89e-5 (favourable) Expressed in all Mixed seminal vesicle: 49.5 Cell line enhanced TIME: 40.5 +DLAT DLTA, PDC-E2 ENSG00000150768 Dihydrolipoamide S-acetyltransferase 11 112024814-112064390 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003782, HPA040786, HPA062766 Enhanced Enhanced Mitochondria Renal cancer:1.95e-14 (favourable), Colorectal cancer:6.19e-6 (favourable), Liver cancer:7.49e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 31.0 Expressed in all +PIH1D2 ENSG00000150773 PIH1 domain containing 2 11 112064010-112074274 Predicted intracellular proteins Evidence at protein level HPA039496 Uncertain Nucleoplasm
Cytosol Mixed Group enriched 7 fallopian tube: 35.4;testis: 126.7 thyroid gland: 11.6 Mixed +C11orf57 FLJ10726 ENSG00000150776 Chromosome 11 open reading frame 57 11 112074086-112085150 Predicted intracellular proteins Evidence at protein level HPA039493, HPA039892 Approved Supported Cytosol Liver cancer:2.70e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 26.7 Expressed in all +TIMM8B DDP2, FLJ21744, MGC102866, MGC117373, TIM8B ENSG00000150779 Translocase of inner mitochondrial membrane 8 homolog B 11 112084800-112086798 Predicted intracellular proteins Evidence at protein level HPA041173 Approved Expressed in all Expressed in all adrenal gland: 39.3 Expressed in all +IL18 IGIF, IL-18, IL-1g, IL1F4 ENSG00000150782 Interleukin 18 11 112143251-112164117 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003980, CAB007772 Enhanced Approved Nucleus
Golgi apparatus
Cytosol Colorectal cancer:2.78e-4 (favourable) Expressed in all Tissue enhanced esophagus: 133.0;skin: 171.5 lymph node: 71.9 Cell line enhanced CAPAN-2: 155.6;HaCaT: 143.7;hTCEpi: 132.7;U-2 OS: 214.0 +TEX12 ENSG00000150783 Testis expressed 12 11 112167372-112172559 Predicted intracellular proteins Evidence at protein level HPA038289, HPA038290 Enhanced Not detected Tissue enriched 38 testis: 32.7 skin: 0.8 Cell line enhanced U-698: 1.0 +PTS PTPS ENSG00000150787 6-pyruvoyltetrahydropterin synthase 11 112226365-112269955 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001481 Uncertain Approved Cytosol Expressed in all Expressed in all adrenal gland: 66.9 Expressed in all +PIP4K2A PIP5K2A, PIP5KIIA, PIP5KIIalpha ENSG00000150867 Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha 10 22534849-22714555 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065440, HPA068771 Supported Approved Golgi apparatus
Plasma membrane
Cytosol Renal cancer:1.46e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 144.3 Expressed in all +C2orf50 FLJ25143 ENSG00000150873 Chromosome 2 open reading frame 50 2 11133053-11146790 Predicted intracellular proteins Evidence at protein level HPA062894 Enhanced Mixed Tissue enriched 10 fallopian tube: 22.7 cerebral cortex: 2.3 Cell line enhanced CAPAN-2: 1.0;T-47d: 1.0 +FREM2 DKFZp686J0811 ENSG00000150893 FRAS1 related extracellular matrix protein 2 13 38687129-38887131 Disease related genes, Predicted membrane proteins Evidence at protein level HPA028831 Uncertain Approved Cytosol Renal cancer:2.23e-7 (favourable) Mixed Tissue enhanced kidney: 8.2;thyroid gland: 8.3 lung: 3.3 Cell line enhanced AF22: 15.4;HAP1: 10.9;MCF7: 6.0;RT4: 5.7;WM-115: 5.8 +FOXO1 FKH1, FKHR, FOXO1A ENSG00000150907 Forkhead box O1 13 40469953-40666597 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001252, CAB022326 Approved Approved Supported Nucleoplasm
Cytosol Renal cancer:1.33e-5 (favourable), Liver cancer:3.74e-4 (favourable) Expressed in all Expressed in all ovary: 80.7 Cell line enhanced HSkMC: 39.2;U-698: 40.3 +CRIM1 S52 ENSG00000150938 Cysteine rich transmembrane BMP regulator 1 2 36355926-36551135 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000556 Enhanced Renal cancer:9.51e-4 (favourable) Expressed in all Expressed in all placenta: 239.7 Cell line enhanced TIME: 540.0 +SEC24D KIAA0755 ENSG00000150961 SEC24 homolog D, COPII coat complex component 4 118722823-118838683 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041626, HPA053486 Approved Approved Vesicles Renal cancer:3.42e-6 (unfavourable) Expressed in all Mixed cervix, uterine: 76.6 Expressed in all +ABCB9 EST122234 ENSG00000150967 ATP binding cassette subfamily B member 9 12 122920951-122981649 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB033052, HPA035113, HPA035114 Approved Supported Vesicles Glioma:4.62e-4 (unfavourable) Mixed Tissue enhanced testis: 23.8 cerebral cortex: 12.0 Mixed +RILPL2 FLJ30380, FLJ32372, MGC7036 ENSG00000150977 Rab interacting lysosomal protein like 2 12 123410683-123436717 Predicted intracellular proteins Evidence at protein level HPA028958 Uncertain Supported Cytosol Endometrial cancer:5.24e-7 (favourable) Expressed in all Mixed bone marrow: 21.6 Expressed in all +DHX37 DDX37, KIAA1517, MGC2695, MGC4322 ENSG00000150990 DEAH-box helicase 37 12 124946825-124989122 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047607 Enhanced Approved Nuclear membrane Liver cancer:9.54e-10 (unfavourable) Expressed in all Mixed bone marrow: 10.0 Expressed in all +UBC ENSG00000150991 Ubiquitin C 12 124911604-124917368 Predicted intracellular proteins Evidence at protein level CAB000362, CAB005419, HPA041344, HPA049132 Supported Renal cancer:7.90e-7 (unfavourable) Expressed in all Expressed in all testis: 1965.2 Expressed in all +ITPR1 ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29 ENSG00000150995 Inositol 1,4,5-trisphosphate receptor type 1 3 4493348-4847840 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA014765, HPA016487 Approved Approved Vesicles Thyroid cancer:3.43e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 106.8 thyroid gland: 47.4 Cell line enhanced HDLM-2: 75.1;HeLa: 38.4;U-87 MG: 44.6 +TKTL2 DKFZP434L1717, FLJ32975 ENSG00000151005 Transketolase like 2 4 163471093-163473746 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 495 testis: 103.8 spleen: 0.2 Not detected +PRSS53 POL3S ENSG00000151006 Protease, serine 53 16 31083425-31089628 Enzymes, Predicted secreted proteins Evidence at transcript level HPA034955, HPA034956 Uncertain Mixed Tissue enhanced skin: 1.1 prostate: 0.5 Cell line enhanced SCLC-21H: 5.5 +SLC7A11 xCT ENSG00000151012 Solute carrier family 7 member 11 4 138164097-138242349 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA064215 Supported Vesicles Ovarian cancer:1.77e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 22.4 epididymis: 8.2 Expressed in all +NOCT Ccr4c, CCR4L, CCRN4L, NOC ENSG00000151014 Nocturnin 4 139015789-139045939 Enzymes, Predicted intracellular proteins Evidence at protein level HPA012287, HPA053714 Uncertain Supported Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:1.05e-5 (unfavourable), Lung cancer:5.28e-5 (unfavourable), Urothelial cancer:6.23e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 21.2 gallbladder: 8.4 Expressed in all +ENKUR C10orf63, CFAP106, enkurin, MGC26778 ENSG00000151023 Enkurin, TRPC channel interacting protein 10 24981979-25062279 Predicted intracellular proteins Evidence at protein level HPA037593, HPA037594, HPA061503 Enhanced Tissue enhanced Tissue enhanced fallopian tube: 69.4 cerebral cortex: 15.2 Cell line enhanced AN3-CA: 1.4;CAPAN-2: 2.3 +GPR158 KIAA1136 ENSG00000151025 G protein-coupled receptor 158 10 25175062-25602226 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013185 Uncertain Approved Cytosol Mixed Tissue enriched 17 cerebral cortex: 17.9 testis: 1.0 Cell line enhanced HEL: 18.7;T-47d: 5.2 +LYZL2 ENSG00000151033 Lysozyme like 2 10 30611779-30629762 Enzymes, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 670 testis: 67.0 all non-specific tissues: 0.0 Cell line enriched 6 SK-BR-3: 2.2 +CACNA2D4 ENSG00000151062 Calcium voltage-gated channel auxiliary subunit alpha2delta 4 12 1791957-1918836 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA031952 Uncertain Mixed Not detected placenta,testis: 0.8 Cell line enhanced Hep G2: 6.4;HL-60: 4.5;HMC-1: 24.8;NB-4: 8.3 +DCP1B FLJ31638 ENSG00000151065 Decapping mRNA 1B 12 1946054-2004535 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039709, HPA058778 Approved Supported Vesicles
Cytosol Expressed in all Expressed in all testis: 36.7 Mixed +CACNA1C CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS ENSG00000151067 Calcium voltage-gated channel subunit alpha1 C 12 1970786-2697950 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA039796, CAB079031 Enhanced Approved Mixed Tissue enhanced smooth muscle: 30.9 endometrium: 26.2 Cell line enriched 17 HDLM-2: 188.9 +KCNA6 HBK2, Kv1.6, PPP1R96 ENSG00000151079 Potassium voltage-gated channel subfamily A member 6 12 4809176-4813412 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level CAB011539, HPA014418 Approved Not detected Not detected appendix,duodenum,lymph node: 0.1 Not detected +THRB ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2 ENSG00000151090 Thyroid hormone receptor beta 3 24117160-24495282 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002008, CAB002009, HPA061035 Approved Supported Nuclear bodies Renal cancer:9.46e-8 (favourable) Mixed Mixed cerebral cortex: 36.3 Cell line enhanced K-562: 43.8;RT4: 28.1 +NGLY1 FLJ11005, PNG1 ENSG00000151092 N-glycanase 1 3 25718944-25790039 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA036825 Approved Liver cancer:1.96e-6 (unfavourable), Colorectal cancer:1.17e-5 (favourable) Expressed in all Expressed in all testis: 116.0 Expressed in all +OXSM CEM1, FASN2D, FLJ20604, KS ENSG00000151093 3-oxoacyl-ACP synthase, mitochondrial 3 25782917-25794534 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021293, HPA021300, HPA021337 Enhanced Approved Mitochondria
Cytosol Renal cancer:4.18e-9 (favourable), Colorectal cancer:1.35e-4 (favourable), Endometrial cancer:5.51e-4 (favourable) Expressed in all Expressed in all testis: 17.4 Mixed +UEVLD Attp, UEV3 ENSG00000151116 UEV and lactate/malate dehyrogenase domains 11 18529609-18588747 Predicted intracellular proteins Evidence at protein level HPA047134 Approved Approved Nucleus
Cytosol Colorectal cancer:7.07e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.8 Mixed +TMEM86A FLJ90119 ENSG00000151117 Transmembrane protein 86A 11 18693122-18704785 Predicted membrane proteins Evidence at transcript level HPA057119 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all Mixed skin: 13.3 Cell line enhanced RPTEC TERT1: 13.2 +C12orf45 MGC40397 ENSG00000151131 Chromosome 12 open reading frame 45 12 104986310-105074197 Predicted intracellular proteins Evidence at protein level HPA038722 Uncertain Approved Nucleoplasm
Nuclear membrane Renal cancer:4.58e-10 (unfavourable) Expressed in all Expressed in all appendix: 14.0 Expressed in all +TMEM263 C12orf23, MGC17943 ENSG00000151135 Transmembrane protein 263 12 106955719-106978778 Predicted intracellular proteins Evidence at protein level HPA042339 Uncertain Thyroid cancer:1.83e-4 (unfavourable), Liver cancer:7.84e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 63.7 Expressed in all +BTBD11 ABTB2B, FLJ33957 ENSG00000151136 BTB domain containing 11 12 107318413-107659642 Predicted intracellular proteins Evidence at protein level HPA055898 Approved Nucleoplasm Mixed Tissue enhanced parathyroid gland: 130.5 thyroid gland: 31.7 Cell line enhanced A549: 22.8;MOLT-4: 14.0 +UBE3B ENSG00000151148 Ubiquitin protein ligase E3B 12 109477402-109536705 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041012 Approved Approved Nuclear speckles
Mitochondria Renal cancer:2.49e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 34.1 Expressed in all +ANK3 ENSG00000151150 Ankyrin 3 10 60026298-60733490 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013249, CAB015179, HPA038455, HPA055643 Approved Approved Plasma membrane Renal cancer:8.88e-16 (favourable) Mixed Expressed in all parathyroid gland: 283.9 Cell line enhanced RT4: 40.1 +IPMK ENSG00000151151 Inositol polyphosphate multikinase 10 58191517-58267934 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037837, HPA057542 Uncertain Enhanced Nucleus Renal cancer:9.96e-7 (unfavourable) Expressed in all Mixed parathyroid gland: 28.3 Mixed +RAD9B FLJ40346 ENSG00000151164 RAD9 checkpoint clamp component B 12 110501655-110532086 Predicted intracellular proteins Evidence at protein level HPA040643 Approved Mixed Tissue enriched 30 testis: 20.5 ovary: 0.6 Cell line enhanced SiHa: 2.6 +PLBD2 p76 ENSG00000151176 Phospholipase B domain containing 2 12 113358566-113391625 Predicted secreted proteins Evidence at protein level HPA017163 Approved Renal cancer:3.58e-11 (unfavourable) Expressed in all Expressed in all adrenal gland: 109.2 Expressed in all +DLG5 KIAA0583, P-dlg ENSG00000151208 Discs large MAGUK scaffold protein 5 10 77790791-77926526 Predicted intracellular proteins Evidence at protein level HPA001746 Supported Cell Junctions Liver cancer:5.38e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 33.8 Mixed +MAT1A MAT, MATA1, SAMS, SAMS1 ENSG00000151224 Methionine adenosyltransferase 1A 10 80271820-80289684 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048627 Supported Tissue enriched Tissue enriched 10 liver: 689.6 epididymis: 68.4 Cell line enriched 11 Hep G2: 64.0 +SLC2A13 HMIT ENSG00000151229 Solute carrier family 2 member 13 12 39755021-40106089 Predicted membrane proteins, Transporters Evidence at protein level HPA006584 Approved Approved Nuclear membrane Mixed Tissue enhanced cerebral cortex: 49.3;parathyroid gland: 74.7 cervix, uterine: 20.4 Mixed +GXYLT1 FLJ43151, GLT8D3 ENSG00000151233 Glucoside xylosyltransferase 1 12 42081845-42144879 Enzymes, Predicted secreted proteins Evidence at protein level Urothelial cancer:3.91e-4 (favourable) Expressed in all Mixed testis: 17.8 Expressed in all +TWF1 A6, PTK9 ENSG00000151239 Twinfilin actin binding protein 1 12 43793723-43806375 Predicted intracellular proteins Evidence at protein level HPA018116 Approved Enhanced Cytosol Liver cancer:1.53e-4 (unfavourable), Colorectal cancer:8.29e-4 (favourable) Expressed in all Expressed in all thyroid gland: 119.5 Expressed in all +DIP2C KIAA0934 ENSG00000151240 Disco interacting protein 2 homolog C 10 274190-689668 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030264, HPA059325 Enhanced Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:2.46e-6 (favourable), Endometrial cancer:8.92e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 23.4 Cell line enhanced U-2197: 30.9 +EIF4E EIF4E1, EIF4EL1, EIF4F ENSG00000151247 Eukaryotic translation initiation factor 4E 4 98871684-98930637 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004077, CAB016316, HPA051311 Supported Enhanced Cytosol
Cytoplasmic bodies Expressed in all Expressed in all testis: 103.5 Expressed in all +MAGI1 AIP3, BAIAP1, BAP1, MAGI-1, TNRC19, WWP3 ENSG00000151276 Membrane associated guanylate kinase, WW and PDZ domain containing 1 3 65353525-66038834 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031851, HPA031852, HPA031853 Enhanced Enhanced Nucleoplasm
Cell Junctions Renal cancer:4.55e-8 (favourable) Expressed in all Mixed thyroid gland: 18.9 Cell line enhanced HEL: 32.4 +TEX30 C13orf27 ENSG00000151287 Testis expressed 30 13 102765990-102773811 Predicted intracellular proteins Evidence at protein level HPA053545 Enhanced Prostate cancer:2.10e-6 (unfavourable), Cervical cancer:2.09e-5 (favourable) Expressed in all Group enriched 7 epididymis: 87.8;testis: 223.6 placenta: 22.3 Cell line enhanced NB-4: 184.1 +CSNK1G3 ENSG00000151292 Casein kinase 1 gamma 3 5 123512099-123617045 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027010 Approved Colorectal cancer:9.90e-5 (favourable) Expressed in all Expressed in all testis: 28.4 Mixed +SRFBP1 BUD22, FLJ25286, p49, Rlb1, STRAP ENSG00000151304 Serum response factor binding protein 1 5 121961961-122075570 Predicted intracellular proteins Evidence at protein level HPA042737, HPA058150 Approved Supported Nucleus
Nucleoli fibrillar center
Vesicles Pancreatic cancer:5.31e-4 (unfavourable) Expressed in all Mixed thyroid gland: 13.8 Expressed in all +AKAP6 ADAP6, AKAP100, KIAA0311, mAKAP, PRKA6 ENSG00000151320 A-kinase anchoring protein 6 14 32329273-32837681 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB001983, HPA048741 Enhanced Mixed Tissue enhanced cerebral cortex: 49.0;heart muscle: 36.0 skeletal muscle: 16.6 Cell line enhanced fHDF/TERT166: 12.2 +NPAS3 bHLHe12, MOP6, PASD6 ENSG00000151322 Neuronal PAS domain protein 3 14 32934933-33804176 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002892 Enhanced Approved Nucleoplasm Tissue enhanced Tissue enhanced cerebral cortex: 24.9 cervix, uterine: 10.1 Group enriched 8 AF22: 9.3;U-266/70: 17.8;U-266/84: 5.0 +FAM177A1 C14orf24 ENSG00000151327 Family with sequence similarity 177 member A1 14 35044907-35113130 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053222, HPA055440 Uncertain Approved Nucleoplasm
Vesicles Ovarian cancer:8.51e-5 (favourable), Head and neck cancer:9.70e-4 (unfavourable) Expressed in all Expressed in all prostate: 103.2 Expressed in all +MBIP ENSG00000151332 MAP3K12 binding inhibitory protein 1 14 36298558-36320676 Predicted intracellular proteins Evidence at protein level HPA003388 Supported Supported Nucleus
Nucleoli
Cytosol Ovarian cancer:1.14e-4 (favourable), Renal cancer:1.25e-4 (favourable), Lung cancer:1.52e-4 (favourable) Expressed in all Expressed in all thyroid gland: 136.4 Expressed in all +MIPOL1 CCDC193 ENSG00000151338 Mirror-image polydactyly 1 14 37197913-37552361 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002893, HPA050179 Enhanced Approved Cytosol Mixed Mixed testis: 13.9 Cell line enhanced HUVEC TERT2: 20.9 +EXT2 SOTV ENSG00000151348 Exostosin glycosyltransferase 2 11 44095549-44245429 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA078409 Supported Golgi apparatus Renal cancer:5.36e-6 (unfavourable), Head and neck cancer:2.50e-4 (unfavourable) Expressed in all Expressed in all placenta: 90.7 Expressed in all +TMEM18 DKFZp434C1714 ENSG00000151353 Transmembrane protein 18 2 667335-677439 Predicted membrane proteins Evidence at protein level HPA040233 Approved Approved Mitochondria Melanoma:3.21e-4 (unfavourable) Expressed in all Expressed in all ovary: 43.8 Expressed in all +ALLC ALC ENSG00000151360 Allantoicase 2 3658195-3702671 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 21 testis: 23.9 gallbladder: 1.1 Cell line enriched 12 U-266/84: 4.2 +KCTD14 MGC2376 ENSG00000151364 Potassium channel tetramerization domain containing 14 11 78015715-78046191 Predicted intracellular proteins Evidence at protein level HPA041118, HPA042181 Enhanced Melanoma:3.96e-5 (unfavourable), Renal cancer:6.92e-5 (favourable), Pancreatic cancer:1.05e-4 (unfavourable), Thyroid cancer:5.93e-4 (favourable), Ovarian cancer:8.01e-4 (favourable) Expressed in all Mixed seminal vesicle: 27.0 Cell line enhanced HBEC3-KT: 18.6;Hep G2: 19.7;RPTEC TERT1: 34.1;U-2 OS: 21.2 +THRSP Lpgp, LPGP1, S14, SPOT14, THRP ENSG00000151365 Thyroid hormone responsive 11 78063861-78068351 Predicted intracellular proteins Evidence at protein level HPA040642 Approved Approved Nucleoplasm Renal cancer:1.16e-4 (unfavourable), Thyroid cancer:3.28e-4 (favourable) Tissue enhanced Tissue enhanced adipose tissue: 231.2;liver: 182.9 breast: 43.6 Cell line enriched 12 ASC diff: 52.2 +NDUFC2 B14.5b, HLC-1 ENSG00000151366 NADH:ubiquinone oxidoreductase subunit C2 11 78068304-78080219 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038873, HPA056195 Approved Supported Mitochondria Renal cancer:5.00e-5 (favourable) Expressed in all Expressed in all thyroid gland: 370.1 Expressed in all +ME3 ENSG00000151376 Malic enzyme 3 11 86441108-86672636 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038473 Approved Urothelial cancer:3.86e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 38.7 Cell line enhanced CAPAN-2: 44.6;TIME: 30.7 +MSGN1 pMesogenin1 ENSG00000151379 Mesogenin 1 2 17816496-17817101 Predicted intracellular proteins, Transcription factors No evidence Not detected Not detected esophagus: 0.4 Not detected +ADAMTS12 ENSG00000151388 ADAM metallopeptidase with thrombospondin type 1 motif 12 5 33523535-33892192 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA035973, HPA075079 Uncertain Approved Nucleoli
Mitochondria Urothelial cancer:6.78e-4 (unfavourable) Mixed Mixed adipose tissue: 9.8 Cell line enhanced hTEC/SVTERT24-B: 48.2;U-2 OS: 38.4 +NUBPL C14orf127, FLJ12660, huInd1, IND1 ENSG00000151413 Nucleotide binding protein like 14 31489956-31861224 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029203 Approved Approved Mitochondria Renal cancer:3.64e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 16.0 Expressed in all +NEK7 ENSG00000151414 NIMA related kinase 7 1 198156963-198322420 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA015520, HPA018193 Approved Supported Nucleoplasm Expressed in all Expressed in all heart muscle: 93.3 Expressed in all +ATP6V1G3 ATP6G3, Vma10 ENSG00000151418 ATPase H+ transporting V1 subunit G3 1 198523222-198540945 Predicted intracellular proteins, Transporters Evidence at protein level HPA028701 Enhanced Tissue enriched Tissue enriched 11 kidney: 21.3 epididymis: 2.0 Cell line enhanced fHDF/TERT166: 1.9 +FER PPP1R74, TYK3 ENSG00000151422 FER tyrosine kinase 5 108747822-109196841 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007641, CAB022464 Approved Supported Cytosol Renal cancer:5.55e-4 (favourable) Expressed in all Mixed parathyroid gland: 19.4 Cell line enhanced RPMI-8226: 62.9 +VIPAS39 C14orf133, hSPE-39, SPE-39, SPE39, VIPAR, VPS16B ENSG00000151445 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 14 77426675-77457952 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003589, HPA003593 Approved Liver cancer:1.06e-6 (unfavourable) Expressed in all Expressed in all testis: 29.2 Expressed in all +ANKRD50 KIAA1223 ENSG00000151458 Ankyrin repeat domain 50 4 124664052-124712732 Predicted intracellular proteins, Transporters Evidence at protein level HPA044008 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:3.28e-4 (unfavourable) Expressed in all Mixed testis: 27.7 Cell line enhanced TIME: 120.1 +UPF2 DKFZP434D222, KIAA1408, RENT2, smg-3 ENSG00000151461 UPF2 regulator of nonsense transcripts homolog (yeast) 10 11920022-12043170 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA067008 Supported Cytosol
Cytoplasmic bodies Liver cancer:6.13e-4 (unfavourable) Expressed in all Expressed in all testis: 36.0 Expressed in all +CDC123 C10orf7, D123 ENSG00000151465 Cell division cycle 123 10 12195965-12250589 Predicted intracellular proteins Evidence at protein level HPA037830, HPA057540 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:3.16e-7 (unfavourable), Renal cancer:2.42e-6 (unfavourable) Expressed in all Expressed in all lymph node: 65.3 Expressed in all +SCLT1 FLJ30655, hCAP-1A ENSG00000151466 Sodium channel and clathrin linker 1 4 128864921-129093607 Predicted intracellular proteins Evidence at protein level HPA036560, HPA036561 Approved Supported Microtubules
Cytosol Mixed Mixed spleen: 11.3 Expressed in all +CCDC3 DKFZp761F241 ENSG00000151468 Coiled-coil domain containing 3 10 12896625-13099652 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA062425 Approved Nucleus
Cytosol Renal cancer:1.38e-5 (unfavourable) Expressed in all Mixed skin: 158.4 Cell line enhanced HAP1: 19.8;HDLM-2: 30.2;U-2 OS: 21.3 +C4orf33 FLJ33703 ENSG00000151470 Chromosome 4 open reading frame 33 4 129093317-129116640 Predicted intracellular proteins Evidence at protein level HPA061199 Uncertain Approved Nuclear bodies
Golgi apparatus Urothelial cancer:2.49e-5 (favourable), Renal cancer:3.04e-4 (favourable) Expressed in all Expressed in all thyroid gland: 28.2 Mixed +FRMD4A bA295P9.4, FLJ10210, FRMD4, KIAA1294 ENSG00000151474 FERM domain containing 4A 10 13643706-14462142 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038449 Uncertain Approved Nucleus
Golgi apparatus Head and neck cancer:2.63e-5 (favourable) Expressed in all Expressed in all adipose tissue: 38.0 Cell line enhanced hTEC/SVTERT24-B: 89.3;TIME: 90.6;WM-115: 154.1 +SLC25A31 ANT4, DKFZP434N1235 ENSG00000151475 Solute carrier family 25 member 31 4 127730378-127774299 Predicted membrane proteins, Transporters Evidence at protein level HPA015064, HPA016841, HPA046835, HPA071684 Uncertain Enhanced Mitochondria Not detected Tissue enriched 852 testis: 85.1 all non-specific tissues: 0.0 Not detected +PTPRO GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2 ENSG00000151490 Protein tyrosine phosphatase, receptor type O 12 15322397-15597399 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA034525 Enhanced Tissue enhanced Tissue enhanced rectum: 33.0 cerebral cortex: 21.7 Cell line enhanced NTERA-2: 6.6;SCLC-21H: 4.7;SH-SY5Y: 8.4 +EPS8 ENSG00000151491 Epidermal growth factor receptor pathway substrate 8 12 15620158-15882329 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003897 Approved Approved Golgi apparatus Renal cancer:1.45e-7 (favourable), Pancreatic cancer:3.33e-7 (unfavourable), Thyroid cancer:5.11e-4 (favourable) Expressed in all Mixed gallbladder: 88.1 Mixed +ACAD8 ENSG00000151498 Acyl-CoA dehydrogenase family member 8 11 134253495-134265855 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040689, HPA043903 Enhanced Renal cancer:6.42e-10 (favourable), Lung cancer:2.38e-4 (favourable), Head and neck cancer:6.19e-4 (favourable), Colorectal cancer:7.62e-4 (favourable) Expressed in all Expressed in all thyroid gland: 43.2 Expressed in all +THYN1 THY28 ENSG00000151500 Thymocyte nuclear protein 1 11 134248279-134253370 Predicted intracellular proteins Evidence at protein level HPA038732, HPA038733 Supported Supported Nucleus
Nucleoli fibrillar center
Cytosol Lung cancer:1.01e-5 (favourable) Expressed in all Expressed in all epididymis: 92.2 Expressed in all +VPS26B MGC10485, Pep8b ENSG00000151502 VPS26, retromer complex component B 11 134224645-134247792 Predicted intracellular proteins Evidence at protein level HPA038172 Uncertain Expressed in all Expressed in all cerebral cortex: 60.4 Expressed in all +NCAPD3 CAP-D3, FLJ42888, hCAP-D3, hcp-6, hHCP-6, KIAA0056 ENSG00000151503 Non-SMC condensin II complex subunit D3 11 134150119-134225454 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040286 Supported Nucleoplasm Tissue enriched Tissue enriched 11 prostate: 194.2 testis: 17.2 Expressed in all +VTI1A MVti1, Vti1-rp2, Vti1a ENSG00000151532 Vesicle transport through interaction with t-SNAREs 1A 10 112446998-112818744 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054108 Supported Supported Golgi apparatus
Vesicles Liver cancer:6.50e-5 (unfavourable), Renal cancer:7.27e-5 (favourable) Expressed in all Mixed parathyroid gland: 12.1 Expressed in all +QDPR DHPR, PKU2, SDR33C1 ENSG00000151552 Quinoid dihydropteridine reductase 4 17460261-17512234 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA058951, HPA065649 Enhanced Approved Mitochondria Renal cancer:7.84e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 226.3 Expressed in all +FAM160B1 bA106M7.3, KIAA1600 ENSG00000151553 Family with sequence similarity 160 member B1 10 114821744-114899832 Predicted intracellular proteins Evidence at protein level HPA043624 Uncertain Approved Nuclear speckles
Cytosol Renal cancer:4.02e-6 (unfavourable) Expressed in all Expressed in all testis: 34.4 Expressed in all +ANO4 FLJ34221, FLJ34272, FLJ35277, TMEM16D ENSG00000151572 Anoctamin 4 12 100717526-101128641 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA053412 Uncertain Renal cancer:5.48e-5 (favourable) Mixed Group enriched 6 adrenal gland: 17.6;cerebral cortex: 10.0;cervix, uterine: 12.6;endometrium: 8.4;ovary: 10.9;prostate: 11.7;seminal vesicle: 11.4 testis: 2.0 Cell line enhanced fHDF/TERT166: 14.2;SK-MEL-30: 13.3;TIME: 26.1;WM-115: 10.6 +TEX9 ENSG00000151575 Testis expressed 9 15 56244009-56445997 Predicted intracellular proteins Evidence at protein level HPA039415 Uncertain Approved Plasma membrane
Cytosol Mixed Mixed fallopian tube: 44.5 Mixed +QTRT2 FLJ12960, QTRTD1 ENSG00000151576 Queuine tRNA-ribosyltransferase accessory subunit 2 3 114005833-114088422 Predicted intracellular proteins Evidence at protein level HPA036827, HPA036828 Uncertain Approved Nucleoplasm
Intermediate filaments Prostate cancer:6.95e-4 (unfavourable) Expressed in all Expressed in all spleen: 16.3 Expressed in all +DRD3 ENSG00000151577 Dopamine receptor D3 3 114128652-114199407 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Not detected Tissue enriched 13 testis: 1.3 all non-specific tissues: 0.0 Not detected +MMAA cblA ENSG00000151611 Methylmalonic aciduria (cobalamin deficiency) cblA type 4 145618263-145660035 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037361 Approved Approved Cytosol Renal cancer:2.23e-5 (favourable), Urothelial cancer:3.21e-4 (favourable), Colorectal cancer:3.38e-4 (favourable) Expressed in all Mixed liver: 12.3 Mixed +ZNF827 ENSG00000151612 Zinc finger protein 827 4 145757627-145938635 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021166 Uncertain Approved Nucleoplasm Mixed Mixed prostate: 37.4 Cell line enhanced WM-115: 67.4 +POU4F2 Brn-3b, BRN3B ENSG00000151615 POU class 4 homeobox 2 4 146638893-146642474 Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Tissue enriched 18 testis: 1.8 all non-specific tissues: 0.0 Cell line enhanced SCLC-21H: 2.1 +EDNRA ENSG00000151617 Endothelin receptor type A 4 147480917-147544954 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013774, CAB018957 Uncertain Renal cancer:1.50e-7 (unfavourable), Stomach cancer:3.93e-4 (unfavourable) Expressed in all Tissue enhanced seminal vesicle: 146.8 cervix, uterine: 83.0 Cell line enhanced ASC TERT1: 11.8;LHCN-M2: 17.3;SH-SY5Y: 16.4 +NR3C2 MLR, MR ENSG00000151623 Nuclear receptor subfamily 3 group C member 2 4 148078762-148444698 Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009155, HPA074979 Enhanced Supported Nucleoplasm Renal cancer:3.10e-11 (favourable) Mixed Mixed thyroid gland: 32.3 Cell line enhanced HUVEC TERT2: 4.9;Karpas-707: 4.5;PC-3: 5.4;RPTEC TERT1: 5.9;TIME: 6.4 +AKR1C2 BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD ENSG00000151632 Aldo-keto reductase family 1 member C2 10 4987400-5018031 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB047304, HPA068265 Enhanced Approved Nucleus
Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Group enriched Group enriched 5 adipose tissue: 330.4;breast: 105.2;esophagus: 94.9;gallbladder: 151.9;liver: 161.4;stomach: 126.5;urinary bladder: 143.0 duodenum: 29.8 Cell line enhanced A549: 1864.0;ASC diff: 1674.9;Hep G2: 2661.0;RT4: 940.6 +DPYSL4 DRP-4, ULIP4 ENSG00000151640 Dihydropyrimidinase like 4 10 132186900-132205776 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049066 Approved Approved Vesicles
Mitochondria Urothelial cancer:3.11e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 30.0 heart muscle: 7.5 Cell line enhanced AF22: 51.3;AN3-CA: 63.4;SH-SY5Y: 74.6 +VENTX HPX42B, VENTX2 ENSG00000151650 VENT homeobox 10 133237404-133241929 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050955 Uncertain Uncertain Nucleoli fibrillar center
Cytosol Tissue enriched Mixed appendix: 4.7 Group enriched 22 NB-4: 10.5;NTERA-2: 9.2 +ADAM8 CD156, CD156a, MS2 ENSG00000151651 ADAM metallopeptidase domain 8 10 133262403-133276868 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA064637 Approved Renal cancer:3.99e-10 (unfavourable) Expressed in all Tissue enhanced bone marrow: 43.8;spleen: 32.9 appendix: 30.1 Cell line enhanced A-431: 51.7;BEWO: 78.4;CAPAN-2: 61.7;HaCaT: 61.1;HDLM-2: 42.3;U-87 MG: 33.6 +ITIH2 H2P ENSG00000151655 Inter-alpha-trypsin inhibitor heavy chain 2 10 7703269-7749520 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA059150 Supported Approved Golgi apparatus Liver cancer:1.48e-4 (favourable) Tissue enriched Tissue enriched 208 liver: 1093.4 cerebral cortex: 5.2 Cell line enriched 896 Hep G2: 735.5 +KIN KIN17, Rts2 ENSG00000151657 Kin17 DNA and RNA binding protein 10 7750962-7787981 Predicted intracellular proteins Evidence at protein level CAB016339, HPA038700 Enhanced Nucleus Renal cancer:1.44e-7 (unfavourable), Urothelial cancer:3.23e-5 (favourable) Expressed in all Mixed endometrium: 5.6 Expressed in all +PIGF ENSG00000151665 Phosphatidylinositol glycan anchor biosynthesis class F 2 46580937-46617119 Predicted membrane proteins Evidence at protein level HPA051389 Uncertain Liver cancer:1.39e-5 (unfavourable) Expressed in all Expressed in all testis: 47.1 Expressed in all +ANKAR FLJ25415 ENSG00000151687 Ankyrin and armadillo repeat containing 2 189674290-189761193 Predicted intracellular proteins Evidence at transcript level HPA036168 Uncertain Approved Nucleus
Microtubule organizing center Mixed Tissue enriched 7 testis: 10.3 parathyroid gland: 1.4 Not detected +INPP1 ENSG00000151689 Inositol polyphosphate-1-phosphatase 2 190343470-190371665 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036698, HPA036699 Supported Approved Vesicles Thyroid cancer:1.12e-5 (favourable), Urothelial cancer:5.70e-4 (favourable) Expressed in all Expressed in all testis: 73.6 Mixed +MFSD6 FLJ20160 ENSG00000151690 Major facilitator superfamily domain containing 6 2 190408355-190509205 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA022274 Approved Approved Nucleoplasm
Actin filaments
Cytosol Renal cancer:1.05e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 79.0 Cell line enhanced HDLM-2: 73.8 +RNF144A KIAA0161, RNF144, UBCE7IP4 ENSG00000151692 Ring finger protein 144A 2 6917392-7068286 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049939 Approved Approved Vesicles Stomach cancer:7.32e-5 (unfavourable), Endometrial cancer:6.00e-4 (unfavourable), Head and neck cancer:6.96e-4 (favourable) Expressed in all Mixed endometrium: 43.1 Cell line enhanced HMC-1: 112.4 +ASAP2 CENTB3, DDEF2, KIAA0400, PAP, SHAG1 ENSG00000151693 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2 9206765-9405683 Predicted intracellular proteins Evidence at protein level CAB018615 Approved Supported Cytosol Endometrial cancer:1.61e-4 (unfavourable), Pancreatic cancer:4.68e-4 (unfavourable) Expressed in all Tissue enhanced testis: 73.6 thyroid gland: 32.6 Mixed +ADAM17 CD156B, cSVP, TACE ENSG00000151694 ADAM metallopeptidase domain 17 2 9488486-9555792 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA010738, CAB025906, HPA051575 Approved Supported Cytosol Urothelial cancer:4.23e-5 (unfavourable) Expressed in all Expressed in all placenta: 33.8 Expressed in all +FLI1 EWSR2, SIC-1 ENSG00000151702 Fli-1 proto-oncogene, ETS transcription factor 11 128686535-128813267 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA073099 Supported Nucleus
Nuclear bodies Renal cancer:4.60e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 46.1 placenta: 15.6 Cell line enhanced HEL: 93.0;HUVEC TERT2: 46.8;REH: 44.4;TIME: 47.8 +KCNJ1 Kir1.1, ROMK1 ENSG00000151704 Potassium voltage-gated channel subfamily J member 1 11 128836315-128867373 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA026962 Enhanced Tissue enriched Tissue enriched 117 kidney: 210.8 epididymis: 1.7 Cell line enriched 42 RPTEC TERT1: 87.0 +TMEM45B BC016153, FLJ40787 ENSG00000151715 Transmembrane protein 45B 11 129815819-129860003 Predicted membrane proteins Evidence at protein level HPA015878 Approved Uncertain Nucleoplasm
Cytosol Expressed in all Tissue enhanced duodenum: 136.2;small intestine: 139.1 rectum: 103.3 Cell line enhanced CACO-2: 32.2;Hep G2: 27.4;PC-3: 45.6;RT4: 105.7;T-47d: 34.7 +WWC2 BOMB, FLJ22029 ENSG00000151718 WW and C2 domain containing 2 4 183099293-183320777 Predicted intracellular proteins Evidence at protein level HPA044005 Uncertain Approved Microtubules Cervical cancer:8.61e-4 (unfavourable), Renal cancer:9.29e-4 (favourable) Expressed in all Mixed lung: 42.5 Mixed +CENPU CENP-50, CENP-U, KLIP1, MLF1IP, PBIP1 ENSG00000151725 Centromere protein U 4 184694618-184734133 Predicted intracellular proteins Evidence at protein level HPA022048 Approved Supported Nucleus
Microtubule organizing center Renal cancer:1.11e-9 (unfavourable), Pancreatic cancer:2.09e-4 (unfavourable), Lung cancer:7.51e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 45.6;testis: 67.6 lymph node: 25.3 Mixed +ACSL1 ACS1, FACL1, FACL2, LACS, LACS1, LACS2 ENSG00000151726 Acyl-CoA synthetase long-chain family member 1 4 184755595-184826818 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011316, HPA011964 Enhanced Supported Nucleus
Mitochondria Renal cancer:1.25e-5 (favourable) Expressed in all Expressed in all adipose tissue: 824.0 Expressed in all +SLC25A4 ANT1, PEO2, PEO3, T1 ENSG00000151729 Solute carrier family 25 member 4 4 185143241-185150382 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046835, HPA071684 Approved Enhanced Mitochondria Renal cancer:0.00e+0 (favourable), Pancreatic cancer:3.41e-4 (favourable) Expressed in all Tissue enhanced heart muscle: 122.1;skeletal muscle: 66.2 cerebral cortex: 38.1 Mixed +AMN1 ENSG00000151743 Antagonist of mitotic exit network 1 homolog 12 31671137-31729174 Predicted intracellular proteins Evidence at protein level HPA046157, HPA062290 Uncertain Approved Centrosome Expressed in all Expressed in all testis: 99.8 Mixed +BICD1 ENSG00000151746 BICD cargo adaptor 1 12 32106835-32383633 Predicted intracellular proteins Evidence at protein level HPA041309 Approved Approved Vesicles Renal cancer:2.33e-7 (unfavourable) Mixed Mixed ovary: 29.0 Mixed +SAV1 salvador, WW45, WWP4 ENSG00000151748 Salvador family WW domain containing protein 1 14 50632058-50668331 Predicted intracellular proteins Evidence at protein level HPA001808 Approved Supported Cytosol Renal cancer:3.83e-6 (favourable), Breast cancer:2.92e-5 (favourable) Expressed in all Expressed in all thyroid gland: 58.3 Expressed in all +CCDC122 FLJ31846 ENSG00000151773 Coiled-coil domain containing 122 13 43823909-43879727 Predicted intracellular proteins Evidence at protein level CAB034233, HPA054995, HPA061456 Approved Approved Nucleus
Vesicles Mixed Mixed prostate,thyroid gland: 7.9 Mixed +SERP2 bA269C23.1, C13orf21 ENSG00000151778 Stress associated endoplasmic reticulum protein family member 2 13 44373665-44397714 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038970 Uncertain Renal cancer:1.94e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 52.7;testis: 23.7 epididymis: 11.3 Cell line enhanced LHCN-M2: 3.2;SH-SY5Y: 5.6;U-2197: 4.5 +NBAS NAG ENSG00000151779 Neuroblastoma amplified sequence 2 15166909-15561330 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036817 Approved Approved Nuclear membrane
Nucleoli
Golgi apparatus Urothelial cancer:5.84e-5 (unfavourable), Liver cancer:1.10e-4 (unfavourable) Expressed in all Expressed in all testis: 37.6 Expressed in all +ZNF385D FLJ22419, ZNF659 ENSG00000151789 Zinc finger protein 385D 3 21412222-22373321 Predicted intracellular proteins Evidence at protein level HPA036190 Uncertain Mixed Tissue enhanced cerebral cortex: 4.8 adipose tissue: 3.1 Cell line enhanced ASC TERT1: 2.2;RPTEC TERT1: 3.3;U-87 MG: 8.1 +TDO2 TDO, TPH2 ENSG00000151790 Tryptophan 2,3-dioxygenase 4 155854738-155920406 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039611 Uncertain Uncertain Plasma membrane
Cytosol Tissue enriched Tissue enriched 18 liver: 278.3 appendix: 15.7 Group enriched 5 EFO-21: 7.3;HDLM-2: 14.7;U-87 MG: 8.6 +GUF1 FLJ13220 ENSG00000151806 GUF1 homolog, GTPase 4 44678427-44700926 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003934, HPA024222 Approved Approved Nucleus
Mitochondria Renal cancer:2.66e-6 (favourable), Thyroid cancer:1.65e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 13.4 Expressed in all +SLC35F4 C14orf36, FLJ37712 ENSG00000151812 Solute carrier family 35 member F4 14 57563922-57982194 Predicted membrane proteins, Transporters Evidence at transcript level HPA043853 Uncertain Approved Nucleoli fibrillar center Not detected Tissue enhanced prostate: 1.9;seminal vesicle: 4.9;testis: 1.8 thyroid gland: 1.1 Cell line enhanced RPMI-8226: 1.0;U-87 MG: 2.0 +GABRA2 ENSG00000151834 Gamma-aminobutyric acid type A receptor alpha2 subunit 4 46248427-46475230 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB079061 Supported Tissue enhanced Tissue enriched 7 cerebral cortex: 74.3 epididymis: 11.3 Cell line enhanced U-2 OS: 4.9;U-87 MG: 2.2;WM-115: 2.5 +SACS ARSACS, DKFZp686B15167, DNAJC29, KIAA0730, PPP1R138, SPAX6 ENSG00000151835 Sacsin molecular chaperone 13 23328826-23411513 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017714 Uncertain Renal cancer:6.21e-6 (unfavourable), Endometrial cancer:9.04e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 32.5 cerebral cortex: 16.0 Mixed +CCDC175 C14orf38 ENSG00000151838 Coiled-coil domain containing 175 14 59504539-59576831 Predicted intracellular proteins Evidence at protein level HPA004200 Uncertain Approved Nucleus
Nucleoli
Cytosol Not detected Tissue enriched 8 testis: 4.0 fallopian tube,rectum: 0.4 Not detected +PABPC3 PABP3, PABPL3, tPABP ENSG00000151846 Poly(A) binding protein cytoplasmic 3 13 25095868-25099254 Predicted intracellular proteins Evidence at protein level HPA045423, HPA067156 Approved Approved Cytosol Ovarian cancer:8.00e-4 (unfavourable) Mixed Tissue enriched 151 testis: 60.6 cerebral cortex: 0.4 Cell line enriched 9 U-266/84: 4.3 +CENPJ BM032, CPAP, LAP, LIP1, MCPH6, Sas-4, SASS4, SCKL4 ENSG00000151849 Centromere protein J 13 24882284-24922889 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA060426 Approved Nucleoplasm
Plasma membrane
Centrosome Renal cancer:1.75e-5 (unfavourable) Expressed in all Tissue enhanced testis: 42.8 thyroid gland: 20.5 Expressed in all +FBXO4 FBX4 ENSG00000151876 F-box protein 4 5 41925254-41941743 Predicted intracellular proteins Evidence at protein level HPA003362 Approved Nucleus Renal cancer:1.28e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 21.0 Mixed +TMEM267 C5orf28, FLJ21657 ENSG00000151881 Transmembrane protein 267 5 43444252-43483893 Predicted membrane proteins Evidence at protein level HPA059946 Approved Nucleoplasm Liver cancer:1.59e-4 (unfavourable), Renal cancer:2.85e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 65.0 Expressed in all +CCL28 CCK1, MEC, SCYA28 ENSG00000151882 C-C motif chemokine ligand 28 5 43376645-43412391 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA077434 Supported Pancreatic cancer:1.43e-4 (unfavourable) Mixed Tissue enhanced breast: 71.1;salivary gland: 126.0 thyroid gland: 38.0 Cell line enhanced EFO-21: 12.1;SiHa: 31.8;SK-MEL-30: 12.9;T-47d: 37.8 +PARP8 FLJ21308, pART16 ENSG00000151883 Poly(ADP-ribose) polymerase family member 8 5 50665899-50846522 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049183 Approved Approved Nucleoplasm
Cell Junctions
Midbody ring
Cytosol Urothelial cancer:1.12e-4 (favourable) Expressed in all Expressed in all thyroid gland: 72.9 Cell line enhanced THP-1: 65.6 +GFRA1 GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1 ENSG00000151892 GDNF family receptor alpha 1 10 116056925-116273467 Predicted membrane proteins Evidence at protein level HPA043829 Uncertain Approved Nucleoplasm
Golgi apparatus Tissue enriched Mixed breast: 30.4 Cell line enhanced BJ hTERT+ SV40 Large T+: 41.6;BJ hTERT+ SV40 Large T+ RasG12V: 75.3;EFO-21: 44.6;fHDF/TERT166: 68.9;HBF TERT88: 62.5;MCF7: 45.6;U-251 MG: 45.6 +CACUL1 C10orf46, CAC1, FLJ40409, MGC33215 ENSG00000151893 CDK2 associated cullin domain 1 10 118674167-118755249 Predicted intracellular proteins Evidence at protein level HPA050611 Approved Nucleoplasm Liver cancer:1.34e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 12.2 Expressed in all +DST BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2 ENSG00000151914 Dystonin 6 56457987-56954628 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030200 Uncertain Approved Nucleus
Microtubules
Cytosol Expressed in all Expressed in all skin: 192.1 Cell line enhanced hTCEpi: 351.4;hTERT-HME1: 274.7 +BEND6 bA203B9.1, C6orf65, FLJ30162 ENSG00000151917 BEN domain containing 6 6 56955126-57027342 Predicted intracellular proteins Evidence at protein level HPA031605, HPA052973 Enhanced Approved Nucleus
Plasma membrane Tissue enriched Tissue enriched 6 cerebral cortex: 39.2 cervix, uterine: 6.6 Mixed +TIAL1 TIAR ENSG00000151923 TIA1 cytotoxic granule associated RNA binding protein like 1 10 119571802-119597029 Predicted intracellular proteins Evidence at protein level HPA060962 Approved Nucleus
Vesicles Liver cancer:7.81e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 86.8 Expressed in all +BAG3 ENSG00000151929 BCL2 associated athanogene 3 10 119651370-119677819 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018493, HPA020586 Enhanced Enhanced Plasma membrane
Cytosol Expressed in all Expressed in all skeletal muscle: 98.2 Mixed +GLT1D1 FLJ31978 ENSG00000151948 Glycosyltransferase 1 domain containing 1 12 128853427-128984968 Predicted intracellular proteins Evidence at protein level HPA039051, HPA039052 Enhanced Cytosol Group enriched Tissue enhanced cerebral cortex: 22.4;testis: 28.2 bone marrow: 18.6 Group enriched 7 MOLT-4: 10.5;NTERA-2: 18.0;SCLC-21H: 9.9 +TMEM132D KIAA1944, MOLT, PPP1R153 ENSG00000151952 Transmembrane protein 132D 12 129071725-129903666 Predicted membrane proteins Evidence at protein level HPA010739 Approved Mixed Tissue enriched 12 cerebral cortex: 12.3 testis: 1.0 Cell line enhanced AF22: 2.6;MOLT-4: 3.9;NTERA-2: 1.8 +RBM46 CT68, MGC27016 ENSG00000151962 RNA binding motif protein 46 4 154781213-154828813 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 59 testis: 50.2 thyroid gland: 0.8 Not detected +SCHIP1 SCHIP-1 ENSG00000151967 Schwannomin interacting protein 1 3 159839861-159897360 Predicted intracellular proteins Evidence at protein level HPA003243, HPA069824 Uncertain Approved Nucleus
Nuclear bodies
Plasma membrane
Cell Junctions
Cytosol Glioma:3.78e-4 (favourable) Tissue enriched Tissue enhanced cerebral cortex: 102.8;heart muscle: 53.1 skeletal muscle: 25.5 Cell line enhanced AN3-CA: 45.4;HUVEC TERT2: 48.7;NTERA-2: 29.7;SH-SY5Y: 177.1 +MCHR2 GPR145, MCH2, MCH2R, SLT ENSG00000152034 Melanin concentrating hormone receptor 2 6 99919910-99994247 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Group enriched 47 cerebral cortex: 8.6;testis: 4.3 colon,small intestine: 0.1 Not detected +KCNE4 MiRP3 ENSG00000152049 Potassium voltage-gated channel subfamily E regulatory subunit 4 2 223051814-223198399 Predicted membrane proteins Evidence at protein level HPA011420 Approved Approved Nuclear bodies
Microtubules Renal cancer:2.02e-7 (unfavourable), Colorectal cancer:9.42e-5 (unfavourable) Expressed in all Tissue enhanced smooth muscle: 54.0 endometrium: 33.5 Cell line enriched 6 AN3-CA: 152.4 +AP1S3 ENSG00000152056 Adaptor related protein complex 1 sigma 3 subunit 2 223751686-223838027 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA066782 Approved Supported Vesicles Pancreatic cancer:2.08e-5 (unfavourable), Lung cancer:3.36e-5 (unfavourable) Mixed Tissue enhanced epididymis: 54.2 thyroid gland: 23.6 Cell line enhanced CACO-2: 130.6 +RABGAP1L FLJ38519, HHL, KIAA0471, TBC1D18 ENSG00000152061 RAB GTPase activating protein 1 like 1 174159410-174995308 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054695 Uncertain Approved Nucleoli
Cytosol Lung cancer:1.16e-4 (favourable) Expressed in all Expressed in all heart muscle: 76.6 Expressed in all +CCDC74B DKFZp434E2321 ENSG00000152076 Coiled-coil domain containing 74B 2 130139287-130145134 Predicted intracellular proteins Evidence at transcript level HPA060727 Uncertain Vesicles Renal cancer:1.55e-4 (unfavourable), Breast cancer:4.46e-4 (favourable) Mixed Tissue enhanced fallopian tube: 23.1;testis: 52.0 cervix, uterine: 13.9 Cell line enhanced SCLC-21H: 12.3;SH-SY5Y: 15.8 +TMEM56 FLJ31842 ENSG00000152078 Transmembrane protein 56 1 95117338-95197607 Predicted membrane proteins Evidence at protein level HPA046762 Uncertain Approved Nuclear speckles Tissue enhanced Tissue enhanced liver: 66.1 heart muscle: 16.7 Cell line enhanced RH-30: 34.4 +MZT2B FAM128B, FLJ14346, MOZART2B ENSG00000152082 Mitotic spindle organizing protein 2B 2 130181737-130190729 Predicted intracellular proteins Evidence at protein level HPA051758, HPA052623 Approved Supported Centrosome
Cytosol Renal cancer:9.37e-8 (unfavourable), Liver cancer:9.65e-4 (unfavourable) Expressed in all Expressed in all testis: 81.3 Expressed in all +TUBA3E ENSG00000152086 Tubulin alpha 3e 2 130191743-130198461 Predicted intracellular proteins Evidence at protein level HPA039247, HPA043684, HPA063394 Uncertain Supported Microtubules Mixed Tissue enriched 26 testis: 74.6 heart muscle: 2.9 Group enriched 11 BEWO: 4.0;U-2 OS: 2.7 +ASTN1 ASTN ENSG00000152092 Astrotactin 1 1 176857302-177164973 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA074112 Approved Golgi apparatus
Vesicles Tissue enriched Group enriched 6 adrenal gland: 19.6;cerebral cortex: 66.8 ovary: 7.4 Cell line enhanced Karpas-707: 4.1;NTERA-2: 4.4;SCLC-21H: 3.2;U-2 OS: 3.6;U-266/84: 14.7 +CFC1B ENSG00000152093 Cripto, FRL-1, cryptic family 1B 2 130521197-130528604 Predicted secreted proteins No evidence HPA041773 Uncertain Not detected Not detected pancreas,prostate,rectum: 0.1 Not detected +FAM168B KIAA0280L, MANI ENSG00000152102 Family with sequence similarity 168 member B 2 131047876-131093460 Predicted intracellular proteins Evidence at protein level HPA043778, HPA061659 Enhanced Renal cancer:5.30e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 112.6 Expressed in all +PTPN14 PEZ ENSG00000152104 Protein tyrosine phosphatase, non-receptor type 14 1 214348696-214552449 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB011469, HPA053864, CAB069441 Uncertain Enhanced Nucleoplasm Pancreatic cancer:2.29e-4 (unfavourable), Stomach cancer:5.16e-4 (unfavourable) Expressed in all Mixed skin: 19.9 Mixed +MGAT5 GNT-V ENSG00000152127 Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 2 134119983-134454621 Enzymes, Predicted membrane proteins Evidence at protein level HPA010919 Approved Expressed in all Mixed parathyroid gland: 32.6 Expressed in all +TMEM163 DKFZP566N034, SV31 ENSG00000152128 Transmembrane protein 163 2 134455759-134719000 Predicted membrane proteins, Transporters Evidence at protein level HPA007224 Uncertain Urothelial cancer:3.15e-4 (favourable), Lung cancer:7.94e-4 (favourable) Mixed Mixed lung: 21.5 Cell line enhanced HEL: 18.1;RPTEC TERT1: 50.5;SCLC-21H: 35.5 +GPATCH11 CCDC75, CENP-Y, CENPY, FLJ38348 ENSG00000152133 G-patch domain containing 11 2 37084451-37099244 Predicted intracellular proteins Evidence at protein level HPA038231, HPA038232 Enhanced Supported Nucleus Expressed in all Mixed adipose tissue: 23.8 Expressed in all +HSPB8 CMT2L, E2IG1, H11, HSP22, HspB8 ENSG00000152137 Heat shock protein family B (small) member 8 12 119178642-119221131 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA015876 Approved Supported Cytosol Liver cancer:2.98e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 426.6 Cell line enhanced EFO-21: 74.9;MCF7: 83.7 +GEMIN6 FLJ23459 ENSG00000152147 Gem nuclear organelle associated protein 6 2 38751534-38785000 Predicted intracellular proteins Evidence at protein level HPA035726, HPA035727 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:2.94e-4 (unfavourable) Expressed in all Mixed testis: 28.9 Expressed in all +TMEM178A MGC33926, TMEM178 ENSG00000152154 Transmembrane protein 178A 2 39664982-39717963 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at transcript level HPA052128 Uncertain Approved Nucleus
Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 55.4 kidney: 19.3 Cell line enhanced AF22: 137.1;NTERA-2: 17.7;SCLC-21H: 30.2 +POU4F1 BRN3A, RDC-1 ENSG00000152192 POU class 4 homeobox 1 13 78598362-78603560 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA068024 Enhanced Mixed Tissue enhanced testis: 1.8 tonsil: 0.7 Cell line enhanced HEK 293: 12.9;HEL: 13.8;RH-30: 17.3;SCLC-21H: 20.1;U-266/70: 12.2 +RNF219 C13orf7, FLJ13449 ENSG00000152193 Ring finger protein 219 13 78614291-78659179 Predicted intracellular proteins Evidence at protein level HPA034785, HPA034786 Enhanced Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:4.99e-6 (unfavourable) Expressed in all Mixed testis: 27.3 Mixed +CYSLTR2 CysLT(2), CYSLT2R ENSG00000152207 Cysteinyl leukotriene receptor 2 13 48653711-48711226 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046528 Uncertain Group enriched Tissue enhanced placenta: 36.7;seminal vesicle: 25.0 spleen: 11.4 Cell line enriched 64 HDLM-2: 83.3 +GRID2 GluD2, GluR-delta-2 ENSG00000152208 Glutamate ionotropic receptor delta type subunit 2 4 92303622-93810157 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA056253, HPA058538 Enhanced Tissue enriched Tissue enriched 10 testis: 60.4 cerebral cortex: 6.2 Cell line enhanced SCLC-21H: 1.4;U-2 OS: 8.2;U-266/70: 2.7;WM-115: 1.3 +ARL11 ARLTS1, FLJ33930 ENSG00000152213 ADP ribosylation factor like GTPase 11 13 49628299-49633872 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040855, HPA040887 Uncertain Mixed Tissue enhanced lymph node: 7.6 spleen: 6.3 Cell line enhanced Daudi: 5.3;HMC-1: 8.9;NB-4: 6.7;THP-1: 9.3 +RIT2 RIBA, RIN ENSG00000152214 Ras like without CAAX 2 18 42743227-43115691 Predicted intracellular proteins Evidence at protein level HPA072174 Supported Tissue enriched Tissue enriched 6 cerebral cortex: 18.3 adrenal gland: 2.8 Not detected +SETBP1 KIAA0437, SEB ENSG00000152217 SET binding protein 1 18 44680173-45068510 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049022, HPA057259 Uncertain Supported Nucleus
Nuclear bodies
Cytosol Renal cancer:6.34e-8 (favourable) Mixed Expressed in all seminal vesicle: 13.8 Cell line enhanced AF22: 15.8;Karpas-707: 45.8 +ARL14EP ARF7EP, C11orf46, FLJ38968 ENSG00000152219 ADP ribosylation factor like GTPase 14 effector protein 11 30323051-30338227 Predicted intracellular proteins Evidence at protein level HPA039634, HPA048127 Approved Approved Nucleus
Vesicles
Focal adhesion sites
Cytosol Breast cancer:2.50e-5 (favourable), Liver cancer:5.26e-4 (unfavourable), Urothelial cancer:7.49e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 53.5 Expressed in all +EPG5 hEPG5, KIAA1632 ENSG00000152223 Ectopic P-granules autophagy protein 5 homolog 18 45847609-45967274 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031689 Uncertain Approved Nuclear speckles Renal cancer:4.04e-5 (favourable) Expressed in all Mixed parathyroid gland: 12.3 Expressed in all +PSTPIP2 ENSG00000152229 Proline-serine-threonine phosphatase interacting protein 2 18 45983536-46072272 Predicted intracellular proteins Evidence at protein level HPA040923, HPA040944 Enhanced Approved Nucleus
Plasma membrane
Mitochondria Renal cancer:2.39e-7 (unfavourable) Expressed in all Tissue enhanced bone marrow: 47.2;spleen: 69.7 placenta: 17.3 Cell line enhanced HEL: 91.3;HMC-1: 95.2 +ATP5A1 ATP5A, ATP5AL2, ATPM, hATP1, OMR, ORM ENSG00000152234 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 18 46080248-46104334 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013067, HPA040622, HPA044202 Enhanced Supported Mitochondria Renal cancer:1.22e-15 (favourable) Expressed in all Expressed in all parathyroid gland: 869.9 Expressed in all +HAUS1 CCDC5, FLJ40084, HEI-C, HsT1461 ENSG00000152240 HAUS augmin like complex subunit 1 18 46104332-46128333 Predicted intracellular proteins Evidence at protein level HPA040601, HPA040652 Supported Supported Centrosome
Cytosol Ovarian cancer:1.55e-4 (favourable), Liver cancer:2.45e-4 (unfavourable), Prostate cancer:6.76e-4 (unfavourable) Expressed in all Expressed in all epididymis: 41.4 Expressed in all +C18orf25 ARKL1, MGC12909, RNF111L1 ENSG00000152242 Chromosome 18 open reading frame 25 18 46173553-46266991 Predicted intracellular proteins Evidence at protein level HPA051314, HPA065021 Approved Approved Nucleoplasm
Cytosol Liver cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all esophagus: 38.8 Expressed in all +SPC25 AD024, MGC22228, SPBC25 ENSG00000152253 SPC25, NDC80 kinetochore complex component 2 168834132-168913371 Predicted intracellular proteins Evidence at protein level HPA047144, HPA050544 Approved Enhanced Cytosol Liver cancer:4.74e-6 (unfavourable), Endometrial cancer:8.61e-5 (unfavourable), Lung cancer:9.44e-5 (unfavourable) Mixed Mixed lymph node: 4.9 Mixed +G6PC2 IGRP ENSG00000152254 Glucose-6-phosphatase catalytic subunit 2 2 168901240-168910000 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 12 pancreas: 2.9 testis: 0.2 Not detected +PDK1 ENSG00000152256 Pyruvate dehydrogenase kinase 1 2 172555373-172608669 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017554, HPA027376, HPA059083 Approved Approved Nucleoli
Mitochondria Renal cancer:1.10e-8 (unfavourable), Cervical cancer:7.30e-5 (unfavourable) Expressed in all Expressed in all testis: 22.2 Expressed in all +PTH PTH1 ENSG00000152266 Parathyroid hormone 11 13492055-13496181 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000072, CAB023409, CAB026363, HPA048540 Enhanced Not detected Tissue enriched 109145 parathyroid gland: 59340.8 thyroid gland: 0.5 Not detected +PDE3B HcGIP1 ENSG00000152270 Phosphodiesterase 3B 11 14643723-14872044 Enzymes, Predicted membrane proteins Evidence at protein level HPA056111 Approved Endoplasmic reticulum Pancreatic cancer:7.91e-4 (favourable) Mixed Tissue enhanced adipose tissue: 65.4 testis: 17.4 Mixed +TCF7L1 TCF3 ENSG00000152284 Transcription factor 7 like 1 2 85133410-85310388 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071298 Supported Nucleoplasm
Cytosol Liver cancer:6.16e-5 (unfavourable), Endometrial cancer:1.70e-4 (unfavourable), Renal cancer:2.06e-4 (unfavourable), Stomach cancer:2.72e-4 (unfavourable), Urothelial cancer:5.38e-4 (unfavourable) Expressed in all Mixed adipose tissue,endometrium,thyroid gland: 22.5 Cell line enhanced NTERA-2: 99.6;RH-30: 43.7;T-47d: 41.9 +TGOLN2 TGN38, TGN46, TGN48, TGN51, TTGN2 ENSG00000152291 Trans-golgi network protein 2 2 85318020-85328425 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011489, HPA012609, HPA012723 Enhanced Enhanced Nucleoplasm
Golgi apparatus Expressed in all Expressed in all thyroid gland: 146.3 Expressed in all +SH2D6 FLJ35993 ENSG00000152292 SH2 domain containing 6 2 85418721-85437029 Predicted intracellular proteins Evidence at transcript level HPA053873 Uncertain Mixed Tissue enhanced duodenum: 1.5;testis: 3.1;thyroid gland: 1.4 small intestine: 1.1 Cell line enhanced LHCN-M2: 1.7 +KCNK13 K2p13.1, THIK-1, THIK1 ENSG00000152315 Potassium two pore domain channel subfamily K member 13 14 90061765-90185857 Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level HPA003514 Approved Approved Nuclear speckles
Cell Junctions Mixed Tissue enhanced parathyroid gland: 14.6;testis: 14.4 kidney: 3.3 Cell line enhanced RT4: 1.4 +UHMK1 KIS, Kist ENSG00000152332 U2AF homology motif kinase 1 1 162497251-162529629 Enzymes, Predicted intracellular proteins Evidence at protein level HPA071190 Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 44.2 Expressed in all +ATG10 APG10L, DKFZP586I0418, FLJ13954 ENSG00000152348 Autophagy related 10 5 81972025-82276857 Predicted intracellular proteins Evidence at protein level HPA044163 Approved Approved Nucleus
Nucleoli Liver cancer:3.22e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 22.2 Expressed in all +POC5 C5orf37, FLJ35779, hPOC5, MGC120442, MGC120443, MGC120444 ENSG00000152359 POC5 centriolar protein 5 75674124-75717481 Predicted intracellular proteins Evidence at protein level HPA037509, HPA037510, HPA061521 Approved Approved Nucleus Liver cancer:1.60e-7 (unfavourable), Renal cancer:6.74e-5 (unfavourable), Urothelial cancer:1.09e-4 (favourable) Expressed in all Mixed testis: 36.2 Expressed in all +SPOCK1 SPOCK, testican-1, TIC1 ENSG00000152377 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 5 136975298-137598379 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007450, HPA026770 Uncertain Approved Vesicles Head and neck cancer:1.93e-5 (unfavourable), Renal cancer:3.77e-5 (unfavourable), Colorectal cancer:1.93e-4 (unfavourable), Ovarian cancer:4.72e-4 (unfavourable), Lung cancer:9.08e-4 (unfavourable), Stomach cancer:9.40e-4 (unfavourable) Tissue enriched Tissue enhanced cerebral cortex: 209.2 prostate: 108.0 Cell line enhanced AF22: 299.3;ASC diff: 403.2;HUVEC TERT2: 508.1;U-138 MG: 298.1 +FAM151B UNQ9217 ENSG00000152380 Family with sequence similarity 151 member B 5 80487969-80542563 Predicted intracellular proteins Evidence at protein level HPA043805 Uncertain Approved Cytosol Mixed Mixed bone marrow: 2.8 Mixed +TADA1 ADA1, hADA1, HFI1, STAF42, TADA1L ENSG00000152382 Transcriptional adaptor 1 1 166856510-166876327 Predicted intracellular proteins Evidence at protein level HPA028651 Approved Supported Nucleoplasm
Focal adhesion sites
Cytosol Expressed in all Expressed in all cerebral cortex: 23.9 Expressed in all +GUCY1A2 GC-SA2, GUC1A2 ENSG00000152402 Guanylate cyclase 1 soluble subunit alpha 2 11 106674012-107018524 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB009534 Uncertain Renal cancer:3.02e-5 (unfavourable) Mixed Tissue enhanced placenta: 25.6 endometrium: 21.1 Cell line enhanced BJ hTERT+: 9.5;BJ hTERT+ SV40 Large T+ RasG12V: 13.1;HBF TERT88: 6.9 +CWF19L2 FLJ32343 ENSG00000152404 CWF19-like 2, cell cycle control (S. pombe) 11 107326345-107457844 Predicted intracellular proteins Evidence at protein level HPA038166 Uncertain Approved Nuclear speckles
Cytosol Expressed in all Expressed in all endometrium: 18.0 Expressed in all +JMY FLJ37870, WHAMM2 ENSG00000152409 Junction mediating and regulatory protein, p53 cofactor 5 79236189-79327215 Predicted intracellular proteins Evidence at protein level HPA037508, HPA043308 Uncertain Uncertain Nucleoplasm Renal cancer:3.03e-5 (favourable), Ovarian cancer:1.12e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.6 Cell line enhanced Karpas-707: 31.6 +HOMER1 HOMER-1B, SYN47, Ves-1 ENSG00000152413 Homer scaffolding protein 1 5 79372636-79514217 Predicted intracellular proteins Evidence at protein level CAB004437, HPA036521, HPA036522 Enhanced Approved Cytosol Expressed in all Tissue enhanced cerebral cortex: 48.9 thyroid gland: 25.2 Mixed +XRCC4 ENSG00000152422 X-ray repair cross complementing 4 5 83077498-83353787 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA006801, HPA051538 Enhanced Supported Nucleus Breast cancer:1.80e-5 (unfavourable) Expressed in all Mixed testis: 16.1 Expressed in all +BOLL BOULE ENSG00000152430 Boule homolog, RNA binding protein 2 197726879-197786762 Predicted intracellular proteins Evidence at protein level HPA018678, HPA048813 Enhanced Not detected Tissue enriched 67 testis: 87.9 skeletal muscle: 1.3 Not detected +ZNF547 FLJ31100 ENSG00000152433 Zinc finger protein 547 19 57363477-57379565 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA056001 Uncertain Mixed Mixed thyroid gland: 5.2 Mixed +ZNF773 MGC4728, ZNF419B ENSG00000152439 Zinc finger protein 773 19 57499915-57518404 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA003152 Uncertain Approved Nucleus
Nucleoli fibrillar center Mixed Mixed parathyroid gland: 13.1 Mixed +ZNF776 FLJ38288 ENSG00000152443 Zinc finger protein 776 19 57746796-57758159 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046653, HPA068553 Uncertain Approved Nucleus
Cytosol Cervical cancer:9.74e-4 (unfavourable) Expressed in all Mixed epididymis: 26.3 Mixed +ZNF256 BMZF-3 ENSG00000152454 Zinc finger protein 256 19 57940833-57947675 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055390 Uncertain Supported Nucleus Expressed in all Mixed testis: 7.9 Cell line enhanced HEK 293: 30.4 +SUV39H2 FLJ23414, KMT1B ENSG00000152455 Suppressor of variegation 3-9 homolog 2 10 14878820-14904315 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045901, HPA057554 Enhanced Approved Mitochondria Liver cancer:2.01e-6 (unfavourable), Renal cancer:5.71e-5 (unfavourable), Breast cancer:5.55e-4 (unfavourable) Expressed in all Tissue enriched 12 testis: 73.2 placenta: 6.1 Expressed in all +DCLRE1C A-SCID, ARTEMIS, FLJ11360, SCIDA, SNM1C ENSG00000152457 DNA cross-link repair 1C 10 14897359-14954432 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA069295 Supported Nucleoplasm
Golgi apparatus Renal cancer:9.03e-8 (unfavourable), Head and neck cancer:1.30e-4 (favourable), Ovarian cancer:7.98e-4 (favourable) Expressed in all Mixed lymph node: 16.4 Expressed in all +OLAH FLJ11106, SAST, THEDC1 ENSG00000152463 Oleoyl-ACP hydrolase 10 15032227-15073852 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037947, HPA037948 Enhanced Group enriched Tissue enriched 7 testis: 46.0 breast: 6.2 Cell line enhanced hTCEpi: 3.3;LHCN-M2: 3.0;SK-BR-3: 4.2 +RPP38 ENSG00000152464 Ribonuclease P/MRP subunit p38 10 15097180-15139818 Enzymes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA045128, HPA050398 Approved Supported Nucleoli Urothelial cancer:2.89e-6 (favourable), Liver cancer:1.46e-4 (unfavourable), Renal cancer:6.25e-4 (unfavourable) Expressed in all Expressed in all testis: 76.3 Expressed in all +NMT2 ENSG00000152465 N-myristoyltransferase 2 10 15102584-15168693 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001303 Approved Supported Golgi apparatus
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 39.4 Cell line enhanced TIME: 123.2 +ZSCAN1 FLJ33779, ZNF915 ENSG00000152467 Zinc finger and SCAN domain containing 1 19 58034032-58054631 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007938 Uncertain Approved Nucleoli Ovarian cancer:7.36e-4 (favourable) Mixed Tissue enhanced epididymis: 7.4 cerebral cortex: 5.3 Cell line enhanced EFO-21: 2.8;HMC-1: 1.8;NTERA-2: 2.1;T-47d: 2.9 +ZNF837 ENSG00000152475 Zinc finger protein 837 19 58367618-58381060 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042833 Uncertain Approved Nucleoli Renal cancer:1.76e-5 (favourable), Endometrial cancer:1.27e-4 (favourable) Expressed in all Mixed skin,spleen: 1.4 Cell line enhanced HEK 293: 8.6 +USP12 USP12L1 ENSG00000152484 Ubiquitin specific peptidase 12 13 27066142-27171896 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007288 Uncertain Expressed in all Expressed in all bone marrow: 45.6 Expressed in all +CCDC50 C3orf6, DFNA44, Ymer ENSG00000152492 Coiled-coil domain containing 50 3 191329077-191398670 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001336 Approved Supported Cytosol Liver cancer:2.48e-5 (unfavourable) Expressed in all Expressed in all gallbladder: 49.2 Mixed +CAMK4 CaMK-GR ENSG00000152495 Calcium/calmodulin dependent protein kinase IV 5 111223653-111494886 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB004347, HPA011753, HPA017206 Approved Supported Nucleoplasm
Nucleoli fibrillar center Mixed Tissue enhanced cerebral cortex: 16.5;testis: 17.0 lymph node: 9.7 Cell line enhanced HDLM-2: 83.9;SH-SY5Y: 35.7 +TRIM36 HAPRIN, RBCC728, RNF98 ENSG00000152503 Tripartite motif containing 36 5 115124762-115180546 Enzymes, Predicted intracellular proteins Evidence at protein level HPA061321 Approved Nucleus
Cytosol Tissue enhanced Tissue enriched 16 testis: 313.5 cerebral cortex: 19.9 Cell line enhanced RH-30: 23.2;SCLC-21H: 31.3;SH-SY5Y: 20.6 +ZFP36L2 BRF2, ERF2, RNF162C, TIS11D ENSG00000152518 ZFP36 ring finger protein like 2 2 43222402-43226609 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047428 Approved Expressed in all Expressed in all thyroid gland: 274.7 Expressed in all +PAN3 ENSG00000152520 PAN3 poly(A) specific ribonuclease subunit 13 28138506-28295335 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028817 Approved Expressed in all Expressed in all spleen: 28.7 Expressed in all +PLEKHH2 KIAA2028, PLEKHH1L ENSG00000152527 Pleckstrin homology, MyTH4 and FERM domain containing H2 2 43637273-43767987 Predicted intracellular proteins Evidence at protein level HPA077225 Supported Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Tissue enhanced Mixed endometrium: 32.1 Mixed +PFKM PFK-1, PFKX, PPP1R122 ENSG00000152556 Phosphofructokinase, muscle 12 48105139-48146404 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002117 Approved Approved Endoplasmic reticulum Renal cancer:2.28e-7 (favourable), Endometrial cancer:5.85e-6 (unfavourable), Head and neck cancer:7.91e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 549.3 Expressed in all +TMEM123 KCT3, PORIMIN ENSG00000152558 Transmembrane protein 123 11 102396332-102470384 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB026001, HPA062862 Supported Golgi apparatus
Vesicles
Cytosol Pancreatic cancer:2.66e-4 (unfavourable), Melanoma:5.36e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 575.8 Mixed +GRIA4 GluA4, GLUR4, GLURD ENSG00000152578 Glutamate ionotropic receptor AMPA type subunit 4 11 105609994-105982092 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Group enriched Tissue enriched 10 cerebral cortex: 73.2 adrenal gland: 7.3 Cell line enhanced AF22: 11.9;NTERA-2: 4.0;SCLC-21H: 5.1 +IGSF10 CMF608, FLJ25972 ENSG00000152580 Immunoglobulin superfamily member 10 3 151425384-151458709 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012921 Uncertain Approved Nucleoplasm
Intermediate filaments Mixed Tissue enhanced ovary: 18.1 gallbladder: 14.7 Cell line enhanced HeLa: 31.1;HL-60: 18.4;REH: 15.7;RPMI-8226: 38.1 +SPEF2 CT122, FLJ23577, KPL2 ENSG00000152582 Sperm flagellar 2 5 35617844-35814611 Predicted intracellular proteins Evidence at protein level HPA039606, HPA040343 Enhanced Mixed Mixed fallopian tube: 25.5 Cell line enhanced HDLM-2: 12.3 +SPARCL1 MAST9 ENSG00000152583 SPARC like 1 4 87473335-87531061 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026225 Enhanced Urothelial cancer:3.33e-4 (unfavourable), Colorectal cancer:4.06e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 2035.8 Cell line enhanced AF22: 23.6;U-266/70: 7.1 +DSPP DFNA39, DGI1, DMP3 ENSG00000152591 Dentin sialophosphoprotein 4 87608529-87616910 Disease related genes, Predicted secreted proteins Evidence at protein level HPA036230 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +DMP1 ENSG00000152592 Dentin matrix acidic phosphoprotein 1 4 87650307-87664361 Disease related genes, Predicted secreted proteins Evidence at protein level HPA037465 Approved Not detected Not detected testis: 0.8 Not detected +MEPE ENSG00000152595 Matrix extracellular phosphoglycoprotein 4 87821411-87846817 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038003, HPA038004 Uncertain Not detected Tissue enriched 41 cerebral cortex: 4.0 all non-specific tissues: 0.0 Not detected +MBNL1 EXP, EXP35, EXP40, EXP42, KIAA0428, MBNL ENSG00000152601 Muscleblind like splicing regulator 1 3 152243828-152465780 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016398, HPA035098 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:2.90e-7 (unfavourable) Expressed in all Expressed in all smooth muscle: 169.7 Expressed in all +CAPSL MGC26610 ENSG00000152611 Calcyphosine like 5 35904295-35938779 Predicted intracellular proteins Evidence at protein level HPA046811, HPA058495 Enhanced Approved Nucleus
Microtubules Group enriched Tissue enriched 10 fallopian tube: 175.4 testis: 17.4 Cell line enhanced BJ hTERT+ SV40 Large T+: 6.8;BJ hTERT+ SV40 Large T+ RasG12V: 6.0;HBF TERT88: 4.6;REH: 7.2;U-698: 13.2 +NADK2 C5orf33, FLJ30596, MNADK, NADKD1 ENSG00000152620 NAD kinase 2, mitochondrial 5 36192592-36242279 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038366, HPA038367, HPA061492 Enhanced Expressed in all Expressed in all liver: 173.0 Expressed in all +GPD1L KIAA0089 ENSG00000152642 Glycerol-3-phosphate dehydrogenase 1-like 3 32105689-32168713 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Renal cancer:3.33e-15 (favourable), Liver cancer:1.35e-5 (unfavourable), Lung cancer:5.71e-5 (favourable), Colorectal cancer:7.05e-4 (favourable) Expressed in all Expressed in all prostate: 92.5 Expressed in all +GJA1 CX43, GJAL, ODD, ODDD, ODOD, SDTY3 ENSG00000152661 Gap junction protein alpha 1 6 121435692-121449727 Cancer-related genes, Disease related genes, Predicted membrane proteins Evidence at protein level CAB010753, HPA035097, HPA047551, HPA069245 Enhanced Supported Supported Nucleoplasm
Vesicles
Cell Junctions Stomach cancer:4.99e-5 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 651.5 skin: 469.0 Cell line enhanced HUVEC TERT2: 306.6;NTERA-2: 370.8;U-87 MG: 348.4 +CCNO CCNU, FLJ22422, UDG2, UNG2 ENSG00000152669 Cyclin O 5 55231152-55233680 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050090 Uncertain Stomach cancer:5.10e-4 (favourable), Endometrial cancer:6.78e-4 (favourable), Lung cancer:7.60e-4 (favourable) Expressed in all Tissue enhanced testis: 6.9 fallopian tube,seminal vesicle: 1.6 Cell line enhanced BEWO: 4.2;T-47d: 5.6 +DDX4 VASA ENSG00000152670 DEAD-box helicase 4 5 55738017-55817157 Enzymes, Predicted intracellular proteins Evidence at protein level CAB026170, HPA037763, HPA037764 Enhanced Tissue enriched Tissue enriched 526 testis: 270.5 tonsil: 0.5 Cell line enhanced BEWO: 1.8 +CLEC4F CLECSF13, FLJ39110, KCLR ENSG00000152672 C-type lectin domain family 4 member F 2 70808643-70820600 Predicted membrane proteins Evidence at transcript level Mixed Mixed small intestine: 4.9 Cell line enhanced AN3-CA: 1.7 +SLC30A6 FLJ31101, ZNT6 ENSG00000152683 Solute carrier family 30 member 6 2 32165841-32224379 Predicted membrane proteins, Transporters Evidence at protein level HPA055032, HPA057328 Uncertain Enhanced Golgi apparatus Liver cancer:9.58e-6 (unfavourable), Endometrial cancer:6.55e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 19.8 Expressed in all +PELO ENSG00000152684 Pelota homolog (Drosophila) 5 52787940-52804046 Predicted intracellular proteins Evidence at protein level HPA031458 Approved Approved Nucleoli fibrillar center Breast cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 20.0 Expressed in all +RASGRP3 CalDAG-GEFIII, GRP3, KIAA0846 ENSG00000152689 RAS guanyl releasing protein 3 2 33436324-33564750 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA058937 Approved Nucleoplasm
Golgi apparatus Mixed Mixed lymph node: 33.8 Group enriched 5 Daudi: 64.5;HEL: 85.5;U-266/70: 109.3;U-266/84: 41.0;U-698: 27.2 +SAR1B SARA2 ENSG00000152700 Secretion associated Ras related GTPase 1B 5 134601144-134649271 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006923, HPA048368 Supported Approved Endoplasmic reticulum Liver cancer:6.59e-4 (favourable), Endometrial cancer:7.11e-4 (favourable) Expressed in all Expressed in all testis: 118.6 Expressed in all +CATSPER3 CACRC ENSG00000152705 Cation channel sperm associated 3 5 134967906-135011707 Predicted membrane proteins, Transporters Evidence at transcript level Mixed Tissue enriched 26 testis: 38.6 fallopian tube: 1.4 Cell line enhanced BJ hTERT+ SV40 Large T+: 2.5 +GPR180 ITR ENSG00000152749 G protein-coupled receptor 180 13 94601903-94634645 Predicted membrane proteins Evidence at protein level HPA047250 Approved Approved Vesicles Renal cancer:3.18e-5 (unfavourable) Expressed in all Mixed adipose tissue: 6.3 Mixed +TCTEX1D1 FLJ40873 ENSG00000152760 Tctex1 domain containing 1 1 66752459-66778787 Predicted intracellular proteins Evidence at protein level HPA028420 Uncertain Tissue enriched Tissue enhanced fallopian tube: 16.6;placenta: 9.6 liver: 4.0 Group enriched 6 HEL: 14.3;HUVEC TERT2: 13.0;THP-1: 12.0 +WDR78 DIC4, FLJ23129 ENSG00000152763 WD repeat domain 78 1 66812885-66924887 Predicted intracellular proteins Evidence at protein level Renal cancer:9.60e-5 (favourable) Mixed Group enriched 5 fallopian tube: 43.8;testis: 62.9 parathyroid gland: 10.2 Cell line enhanced RPTEC TERT1: 8.6 +ANKRD22 MGC22805 ENSG00000152766 Ankyrin repeat domain 22 10 88822132-88851818 Predicted intracellular proteins Evidence at protein level HPA012922 Approved Approved Nucleus Endometrial cancer:8.73e-6 (favourable), Pancreatic cancer:6.15e-4 (unfavourable) Expressed in all Tissue enhanced skin: 38.6;stomach: 49.2 esophagus: 27.0 Cell line enhanced A-431: 13.9;CAPAN-2: 43.6;RT4: 27.0;T-47d: 21.2 +FARP1 CDEP, MGC87400, PLEKHC2, PPP1R75 ENSG00000152767 FERM, ARH/RhoGEF and pleckstrin domain protein 1 13 98142562-98455176 Predicted intracellular proteins Evidence at protein level HPA000760 Supported Cytosol Renal cancer:1.39e-5 (favourable) Expressed in all Mixed thyroid gland: 58.8 Mixed +IFIT5 RI58 ENSG00000152778 Interferon induced protein with tetratricopeptide repeats 5 10 89414586-89421001 Predicted intracellular proteins Evidence at protein level HPA037957, HPA062180 Uncertain Supported Vesicles
Plasma membrane Expressed in all Mixed parathyroid gland: 36.2 Cell line enhanced BJ hTERT+ SV40 Large T+: 66.6;BJ hTERT+ SV40 Large T+ RasG12V: 82.7 +SLC16A12 MCT12 ENSG00000152779 Solute carrier family 16 member 12 10 89430299-89556641 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA037587 Approved Mitochondria Renal cancer:4.50e-12 (favourable) Tissue enriched Tissue enhanced epididymis: 63.5;kidney: 93.5 seminal vesicle: 20.2 Cell line enhanced ASC TERT1: 16.2;HSkMC: 6.0 +PANK1 MGC24596, PANK, PANK1a, PANK1b ENSG00000152782 Pantothenate kinase 1 10 89579497-89645572 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:1.55e-10 (favourable), Liver cancer:1.50e-4 (favourable) Mixed Tissue enhanced kidney: 46.6;liver: 55.1 duodenum: 20.6 Mixed +PRDM8 KMT8D ENSG00000152784 PR/SET domain 8 4 80183879-80204329 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057253 Approved Nuclear bodies Tissue enhanced Tissue enhanced prostate: 40.8;seminal vesicle: 37.7 cerebral cortex: 23.2 Cell line enhanced LHCN-M2: 34.7;NB-4: 30.5;SCLC-21H: 116.7 +BMP3 ENSG00000152785 Bone morphogenetic protein 3 4 81030965-81057531 Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced urinary bladder: 20.6 lung: 8.7 Cell line enhanced AF22: 10.7;Daudi: 12.2;RT4: 11.3;SK-BR-3: 4.6 +HNRNPDL HNRPDL, JKTBP, laAUF1 ENSG00000152795 Heterogeneous nuclear ribonucleoprotein D like 4 82422564-82430408 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056820, HPA063147 Supported Enhanced Nucleoplasm Expressed in all Expressed in all endometrium: 422.5 Expressed in all +HHEX HEX, HOX11L-PEN, PRHX ENSG00000152804 Hematopoietically expressed homeobox 10 92689951-92695646 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051894, HPA055460 Approved Approved Nucleoplasm
Mitochondria Renal cancer:3.25e-5 (unfavourable), Cervical cancer:3.91e-5 (favourable), Liver cancer:6.23e-4 (unfavourable), Breast cancer:8.83e-4 (favourable) Expressed in all Expressed in all thyroid gland: 164.8 Cell line enhanced HEL: 89.2;HMC-1: 92.9;HUVEC TERT2: 88.4;K-562: 137.7 +UTRN DMDL, DRP, DRP1 ENSG00000152818 Utrophin 6 144285701-144853034 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016348, HPA018894 Enhanced Approved Nucleoplasm
Plasma membrane Renal cancer:7.61e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 174.0 Cell line enhanced HAP1: 226.1 +GRM1 GPRC1A, mGlu1, MGLUR1, PPP1R85 ENSG00000152822 Glutamate metabotropic receptor 1 6 146027646-146437598 Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA015701 Approved Approved Vesicles Not detected Group enriched 5 cerebral cortex: 7.0;heart muscle: 1.7 kidney: 0.8 Not detected +PTPRK R-PTP-kappa ENSG00000152894 Protein tyrosine phosphatase, receptor type K 6 127968779-128520674 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054056, HPA054822 Uncertain Supported Vesicles
Plasma membrane
Cell Junctions Renal cancer:9.33e-5 (favourable), Pancreatic cancer:1.99e-4 (unfavourable) Expressed in all Mixed gallbladder: 27.8 Mixed +GGPS1 GGPPS1 ENSG00000152904 Geranylgeranyl diphosphate synthase 1 1 235327350-235344532 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029472 Enhanced Liver cancer:6.69e-4 (unfavourable) Expressed in all Expressed in all testis: 90.1 Expressed in all +CNTNAP4 CASPR4, KIAA1763 ENSG00000152910 Contactin associated protein like 4 16 76277278-76559238 Predicted membrane proteins Evidence at protein level HPA031859, HPA057342 Enhanced Tissue enriched Tissue enriched 21 cerebral cortex: 35.9 testis: 1.6 Group enriched 6 Daudi: 7.9;HSkMC: 3.0;Karpas-707: 2.6;RPMI-8226: 4.9 +ZNF117 H-plk, HPF9 ENSG00000152926 Zinc finger protein 117 7 64971776-65006684 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031148 Approved Nucleoli fibrillar center
Cytosol Renal cancer:2.17e-11 (unfavourable) Expressed in all Mixed adrenal gland: 25.2 Mixed +RAB3C ENSG00000152932 RAB3C, member RAS oncogene family 5 58582221-58859394 Predicted intracellular proteins Evidence at protein level HPA003160, HPA048156 Enhanced Approved Cytosol Mixed Group enriched 17 adrenal gland: 12.0;cerebral cortex: 55.3 small intestine: 2.0 Cell line enhanced HEL: 2.2;SCLC-21H: 11.9;SH-SY5Y: 3.9 +LMNTD1 FLJ36004, IFLTD1, Pas1c1 ENSG00000152936 Lamin tail domain containing 1 12 25409307-25648579 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA038640, HPA045911 Uncertain Approved Nucleoplasm
Centrosome Tissue enhanced Group enriched 7 fallopian tube: 27.1;testis: 26.6 rectum: 3.7 Cell line enhanced SH-SY5Y: 8.1;U-2197: 24.9 +MARVELD2 DFNB49, FLJ30532, MRVLDC2, TRIC ENSG00000152939 MARVEL domain containing 2 5 69415112-69444330 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018119, HPA061726 Uncertain Supported Cell Junctions Renal cancer:2.84e-13 (favourable) Mixed Tissue enhanced thyroid gland: 19.7 small intestine: 8.7 Cell line enhanced BEWO: 30.0;CAPAN-2: 22.9;HaCaT: 17.6;RT4: 17.7;SCLC-21H: 32.0;T-47d: 18.4 +RAD17 CCYC, RAD17Sp, Rad24 ENSG00000152942 RAD17 checkpoint clamp loader component 5 69369293-69414801 Predicted intracellular proteins Evidence at protein level CAB004551, HPA005448 Approved Enhanced Nucleoplasm Renal cancer:5.79e-6 (favourable) Expressed in all Expressed in all testis: 39.3 Mixed +MED21 SRB7, SURB7 ENSG00000152944 Mediator complex subunit 21 12 27022546-27066343 Predicted intracellular proteins Evidence at protein level HPA017177 Uncertain Approved Nucleus
Nucleoli
Cytosol Renal cancer:3.74e-8 (favourable) Expressed in all Expressed in all testis: 69.4 Expressed in all +PLOD2 LH2 ENSG00000152952 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 3 146069440-146163653 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025898, HPA069126 Approved Uncertain Nucleoli
Cytosol Renal cancer:4.99e-11 (unfavourable), Liver cancer:7.64e-10 (unfavourable), Lung cancer:1.42e-4 (unfavourable), Cervical cancer:1.97e-4 (unfavourable), Stomach cancer:2.83e-4 (unfavourable) Expressed in all Mixed thyroid gland: 150.8 Cell line enhanced HBF TERT88: 615.2;U-87 MG: 554.9 +STK32B HSA250839, STK32, STKG6, YANK2 ENSG00000152953 Serine/threonine kinase 32B 4 5051442-5500998 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA058536 Approved Microtubules Renal cancer:1.63e-8 (favourable) Mixed Tissue enhanced kidney: 15.8 testis: 8.6 Cell line enhanced HUVEC TERT2: 22.9;REH: 22.7;U-2197: 40.5;WM-115: 110.5 +NRSN1 p24, VMP ENSG00000152954 Neurensin 1 6 24126122-24154900 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA061006 Approved Approved Nucleus
Vesicles Tissue enriched Tissue enriched 14 cerebral cortex: 96.3 adrenal gland: 6.6 Cell line enhanced SCLC-21H: 14.0;SH-SY5Y: 10.0 +JAKMIP1 FLJ31564, Gababrbp, JAMIP1, MARLIN1 ENSG00000152969 Janus kinase and microtubule interacting protein 1 4 6026199-6200591 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044570 Uncertain Mixed Tissue enriched 6 cerebral cortex: 38.7 prostate: 6.9 Cell line enhanced Daudi: 11.3;MOLT-4: 36.1;SCLC-21H: 22.4;U-266/70: 20.1 +ZIC1 ZIC, ZNF201 ENSG00000152977 Zic family member 1 3 147393422-147510293 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004098 Supported Supported Nucleoplasm Tissue enhanced Tissue enriched 9 cerebral cortex: 23.8 skin: 2.5 Cell line enriched 5 AF22: 171.9 +ADGRA3 FLJ38547, GPR125, PGR21 ENSG00000152990 Adhesion G protein-coupled receptor A3 4 22345071-22516054 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008904 Uncertain Expressed in all Expressed in all thyroid gland: 42.5 Mixed +CPB1 ENSG00000153002 Carboxypeptidase B1 3 148791102-148860187 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB026158, HPA038069, HPA046340 Enhanced Group enriched Tissue enriched 312 pancreas: 47292.1 ovary: 151.6 Cell line enhanced HDLM-2: 1.0;U-2 OS: 1.7 +SREK1IP1 FLJ36754, P18SRP, SFRS12IP1 ENSG00000153006 SREK1 interacting protein 1 5 64718144-64768685 Predicted intracellular proteins Evidence at protein level HPA045677, HPA062853 Approved Approved Nucleus
Nucleoli Liver cancer:9.03e-4 (unfavourable), Renal cancer:9.68e-4 (unfavourable) Expressed in all Mixed placenta: 12.4 Expressed in all +LGI2 FLJ10675, KIAA1916 ENSG00000153012 Leucine rich repeat LGI family member 2 4 24998847-25030879 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA017140 Approved Approved Centrosome Mixed Tissue enriched 19 parathyroid gland: 371.4 smooth muscle: 19.6 Cell line enhanced AF22: 27.8;RPMI-8226: 9.3;SCLC-21H: 21.4 +CWC27 NY-CO-10, SDCCAG-10, SDCCAG10 ENSG00000153015 CWC27 spliceosome associated protein homolog 5 64768930-65018763 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020344, HPA024149, HPA065809 Approved Enhanced Nucleoplasm Liver cancer:5.27e-6 (unfavourable) Expressed in all Expressed in all testis: 31.1 Expressed in all +MR1 HLALS ENSG00000153029 Major histocompatibility complex, class I-related 1 181033425-181061938 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA048304 Supported Plasma membrane Expressed in all Mixed thyroid gland: 28.2 Mixed +SRP19 ENSG00000153037 Signal recognition particle 19 5 112861222-112869788 Predicted intracellular proteins, Transporters Evidence at protein level HPA029272 Approved Renal cancer:3.72e-10 (unfavourable) Expressed in all Expressed in all thyroid gland: 64.7 Expressed in all +CENPH ENSG00000153044 Centromere protein H 5 69189548-69210357 Predicted intracellular proteins Evidence at protein level HPA036494 Approved Supported Nucleus
Nucleoli Renal cancer:5.11e-15 (unfavourable), Liver cancer:5.22e-5 (unfavourable), Ovarian cancer:2.50e-4 (favourable), Cervical cancer:6.86e-4 (favourable) Expressed in all Tissue enhanced testis: 53.9 lymph node: 20.6 Expressed in all +CDYL CDYL1, DKFZP586C1622 ENSG00000153046 Chromodomain Y-like 6 4706159-4955551 Enzymes, Predicted intracellular proteins Evidence at protein level CAB012249, HPA035578 Enhanced Supported Nuclear speckles Glioma:2.10e-4 (favourable), Liver cancer:2.20e-4 (unfavourable), Melanoma:7.52e-4 (unfavourable) Expressed in all Expressed in all placenta: 27.7 Expressed in all +CARHSP1 CRHSP-24, CSDC1 ENSG00000153048 Calcium regulated heat stable protein 1 16 8852942-8869012 Predicted intracellular proteins Evidence at protein level HPA051911 Approved Urothelial cancer:7.24e-4 (favourable) Expressed in all Expressed in all testis: 260.3 Expressed in all +TEKT5 CT149, FLJ32871 ENSG00000153060 Tektin 5 16 10627501-10694945 Predicted intracellular proteins Evidence at protein level HPA043578 Supported Actin filaments Mixed Tissue enriched 48 testis: 45.6 stomach: 0.9 Cell line enriched 16 BEWO: 12.0 +BANK1 BANK, FLJ20706 ENSG00000153064 B-cell scaffold protein with ankyrin repeats 1 4 101411286-102074812 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037002 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Mixed Group enriched 5 appendix: 45.9;lymph node: 96.8;spleen: 77.4;thyroid gland: 21.6;tonsil: 87.2 urinary bladder: 12.9 Cell line enhanced Daudi: 9.7;HEL: 9.5;HL-60: 7.6;U-266/70: 23.8 +TXNDC11 EFP1 ENSG00000153066 Thioredoxin domain containing 11 16 11679080-11742878 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041174, HPA041390 Supported Supported Plasma membrane
Cytosol Endometrial cancer:2.12e-5 (favourable), Glioma:8.01e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 84.5 Expressed in all +DAB2 DOC-2 ENSG00000153071 DAB2, clathrin adaptor protein 5 39371675-39462300 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009314, HPA028888 Enhanced Enhanced Nucleoli fibrillar center
Vesicles
Plasma membrane Liver cancer:7.38e-6 (unfavourable), Stomach cancer:9.67e-4 (unfavourable) Expressed in all Expressed in all placenta: 321.8 Cell line enhanced fHDF/TERT166: 273.0;U-138 MG: 234.0 +ACMSD ENSG00000153086 Aminocarboxymuconate semialdehyde decarboxylase 2 134838547-134902034 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010533, HPA011179 Enhanced Renal cancer:2.39e-4 (favourable) Group enriched Group enriched 10 kidney: 137.3;liver: 80.2 gallbladder: 10.8 Cell line enriched 16 RPTEC TERT1: 19.7 +ACOXL FLJ11042 ENSG00000153093 Acyl-CoA oxidase-like 2 110732573-111118222 Predicted intracellular proteins Evidence at protein level HPA035392, HPA035393 Supported Nucleoli
Cytosol Urothelial cancer:6.48e-4 (favourable) Group enriched Group enriched 6 epididymis: 9.2;lung: 14.5;parathyroid gland: 6.9;prostate: 5.2;testis: 5.2;urinary bladder: 7.6 thyroid gland: 1.3 Cell line enhanced A-431: 11.1;RPMI-8226: 15.9;RT4: 23.3;U-266/70: 14.6 +BCL2L11 BIM, BimEL, BimL, BimS, BOD ENSG00000153094 BCL2 like 11 2 111119378-111168447 Predicted intracellular proteins, Transporters Evidence at protein level CAB026332 Approved Expressed in all Expressed in all thyroid gland: 33.2 Cell line enhanced U-266/70: 73.4 +ANAPC1 APC1, MCPR, TSG24 ENSG00000153107 Anaphase promoting complex subunit 1 2 111766271-111884690 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036329, HPA036330, HPA042998 Approved Approved Vesicles Endometrial cancer:1.34e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 20.6 Expressed in all +CAST ENSG00000153113 Calpastatin 5 96525267-96779595 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009491, HPA036881, HPA036882 Approved Enhanced Endoplasmic reticulum
Cytosol Stomach cancer:1.20e-5 (unfavourable), Pancreatic cancer:9.27e-5 (unfavourable), Urothelial cancer:4.98e-4 (unfavourable) Expressed in all Expressed in all esophagus: 401.9 Mixed +SCOC HRIHFB2072, SCOCO, UNC-69 ENSG00000153130 Short coiled-coil protein 4 140257286-140385726 Predicted intracellular proteins Evidence at protein level HPA061198, HPA070321 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:4.82e-12 (favourable) Expressed in all Expressed in all cerebral cortex: 187.9 Expressed in all +CLGN ENSG00000153132 Calmegin 4 140388455-140427968 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB020709, HPA048761, HPA058627 Enhanced Enhanced Endoplasmic reticulum Tissue enhanced Tissue enriched 5 testis: 186.4 heart muscle: 35.6 Cell line enhanced U-251 MG: 54.9 +CETN3 CEN3 ENSG00000153140 Centrin 3 5 90392261-90409786 Predicted intracellular proteins Evidence at protein level HPA035608, HPA063704 Approved Supported Centrosome Liver cancer:2.22e-4 (unfavourable) Expressed in all Tissue enriched 6 testis: 225.8 ovary: 36.5 Expressed in all +SMARCA5 hISWI, hSNF2H, ISWI ENSG00000153147 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 4 143513463-143557486 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005227, HPA008751 Supported Supported Nucleus
Nucleoli fibrillar center Liver cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all testis: 59.1 Expressed in all +SYCP2L C6orf177, dJ62D2.1, NO145 ENSG00000153157 Synaptonemal complex protein 2 like 6 10886831-10979320 Predicted intracellular proteins Evidence at protein level HPA034679 Supported Nucleoplasm Tissue enhanced Tissue enriched 20 parathyroid gland: 122.5 testis: 5.9 Cell line enhanced HL-60: 10.7;HMC-1: 35.1;K-562: 9.5;NB-4: 9.1 +BMP6 VGR, VGR1 ENSG00000153162 Bone morphogenetic protein 6 6 7726797-7881422 Predicted secreted proteins Evidence at protein level CAB002773, HPA062683 Approved Approved Mitochondria Breast cancer:6.45e-4 (favourable) Expressed in all Tissue enhanced placenta: 33.4 lung: 10.4 Cell line enhanced HUVEC TERT2: 162.0;Karpas-707: 72.0;SiHa: 90.3;TIME: 73.2 +RGPD3 RGP3 ENSG00000153165 RANBP2-like and GRIP domain containing 3 2 106391290-106468376 Predicted intracellular proteins Evidence at transcript level HPA049497, HPA051675, HPA067564 Uncertain Approved Nuclear membrane
Vesicles Not detected Tissue enriched 13 testis: 11.7 cerebral cortex,kidney: 0.8 Cell line enhanced HEL: 1.4;MOLT-4: 4.1 +RASSF3 ENSG00000153179 Ras association domain family member 3 12 64507001-64697567 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB022664, CAB034035, HPA038469 Supported Supported Plasma membrane
Cytosol Expressed in all Expressed in all smooth muscle: 86.2 Expressed in all +HNRNPU C1orf199, FLJ30202, FLJ37978, hnRNPU, HNRNPU-AS1, HNRPU, NCRNA00201, SAF-A ENSG00000153187 Heterogeneous nuclear ribonucleoprotein U 1 244840638-244864560 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011532, HPA041057, HPA058707 Supported Supported Nucleoplasm Liver cancer:8.88e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 225.2 Expressed in all +RANBP2 ADANE, ANE1, NUP358 ENSG00000153201 RAN binding protein 2 2 108719481-108785811 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564 Supported Expressed in all Expressed in all parathyroid gland: 74.9 Expressed in all +AHCTF1 ELYS ENSG00000153207 AT-hook containing transcription factor 1 1 246839098-246931978 Predicted intracellular proteins, Transporters Evidence at protein level HPA031658 Uncertain Supported Nuclear membrane Renal cancer:3.49e-8 (unfavourable) Expressed in all Expressed in all testis: 61.5 Expressed in all +MERTK c-Eyk, mer, RP38, Tyro12 ENSG00000153208 MER proto-oncogene, tyrosine kinase 2 111898479-112029561 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036196, HPA075622 Approved Approved Endoplasmic reticulum
Plasma membrane
Cytosol Renal cancer:4.43e-5 (favourable), Lung cancer:4.74e-4 (favourable) Expressed in all Mixed adrenal gland: 77.2 Cell line enhanced CACO-2: 31.5;Hep G2: 27.2;HUVEC TERT2: 32.3 +TMEM87B FLJ14681 ENSG00000153214 Transmembrane protein 87B 2 112055223-112119318 Predicted membrane proteins Evidence at protein level HPA035183 Approved Approved Golgi apparatus
Vesicles Renal cancer:1.52e-7 (unfavourable), Cervical cancer:3.78e-4 (unfavourable), Head and neck cancer:4.28e-4 (unfavourable), Liver cancer:4.72e-4 (unfavourable) Expressed in all Mixed prostate: 44.5 Expressed in all +OR14K1 OR5AY1 ENSG00000153230 Olfactory receptor family 14 subfamily K member 1 1 247738615-247739559 G-protein coupled receptors, Predicted membrane proteins No evidence HPA016643 Uncertain Not detected Not detected testis: 0.3 Not detected +PTPRR EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ ENSG00000153233 Protein tyrosine phosphatase, receptor type R 12 70638073-70920843 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB011461, HPA011851, HPA071067 Uncertain Supported Plasma membrane
Cell Junctions
Cytosol Urothelial cancer:1.40e-5 (favourable) Mixed Tissue enhanced cerebral cortex: 20.8 endometrium: 9.0 Group enriched 11 HDLM-2: 18.5;RT4: 29.7;SH-SY5Y: 6.2 +NR4A2 HZF-3, NOT, NURR1, RNR1, TINUR ENSG00000153234 Nuclear receptor subfamily 4 group A member 2 2 156324432-156342348 Cancer-related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000543, CAB010481 Uncertain Supported Nuclear speckles Expressed in all Tissue enhanced adrenal gland: 174.3 ovary: 95.8 Cell line enhanced HeLa: 10.1;HMC-1: 9.6;U-266/70: 11.3 +CCDC148 MGC125588 ENSG00000153237 Coiled-coil domain containing 148 2 158171081-158456753 Predicted intracellular proteins Evidence at protein level HPA042626 Uncertain Approved Nucleus
Nucleoli Thyroid cancer:2.54e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 4.2;testis: 5.8 fallopian tube: 2.4 Cell line enhanced CAPAN-2: 2.2;HBF TERT88: 1.7;SCLC-21H: 2.0 +PLA2R1 CLEC13C, PLA2-R, PLA2G1R, PLA2IR ENSG00000153246 Phospholipase A2 receptor 1 2 159932006-160062610 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB068217, CAB068218 Approved Approved Cytosol Stomach cancer:3.08e-4 (unfavourable) Mixed Tissue enhanced thyroid gland: 70.6 parathyroid gland: 34.5 Cell line enhanced ASC TERT1: 13.7;BJ hTERT+: 13.1;SiHa: 12.5;TIME: 38.6 +RBMS1 C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1 ENSG00000153250 RNA binding motif single stranded interacting protein 1 2 160272151-160493794 Predicted intracellular proteins Evidence at protein level HPA047943, HPA061791 Supported Cytosol Renal cancer:1.33e-7 (unfavourable), Liver cancer:4.45e-4 (unfavourable) Expressed in all Expressed in all placenta: 119.9 Mixed +SCN3A Nav1.3 ENSG00000153253 Sodium voltage-gated channel alpha subunit 3 2 165087522-165204067 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA035396 Approved Tissue enriched Tissue enriched 7 cerebral cortex: 13.6 adrenal gland: 1.9 Cell line enhanced Karpas-707: 7.8;MOLT-4: 26.0;RPTEC TERT1: 11.6;SH-SY5Y: 7.3 +FEZF2 FEZL, FKSG36, FLJ10142, TOF, Zfp312, ZNF312 ENSG00000153266 FEZ family zinc finger 2 3 62369681-62374324 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enhanced Tissue enriched 30 cerebral cortex: 11.7 colon: 0.3 Cell line enhanced AF22: 1.4;NTERA-2: 1.0 +CD96 TACTILE ENSG00000153283 CD96 molecule 3 111292719-111665750 CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066754 Enhanced Renal cancer:2.02e-6 (unfavourable), Urothelial cancer:5.23e-5 (favourable), Head and neck cancer:5.52e-4 (favourable) Mixed Tissue enhanced lymph node: 28.0 urinary bladder: 16.7 Group enriched 8 HEL: 13.0;MOLT-4: 51.4;RT4: 46.0;U-937: 40.7;WM-115: 10.8 +SLC25A27 FLJ33552, UCP4 ENSG00000153291 Solute carrier family 25 member 27 6 46652915-46678193 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA069732 Supported Mitochondria Pancreatic cancer:6.16e-4 (favourable) Expressed in all Mixed epididymis: 85.3 Cell line enhanced HeLa: 29.3 +ADGRF1 GPR110, hGPCR36, PGR19 ENSG00000153292 Adhesion G protein-coupled receptor F1 6 46997703-47042363 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA038438 Approved Renal cancer:1.35e-5 (favourable) Mixed Tissue enhanced esophagus: 14.6;kidney: 17.6;urinary bladder: 18.9 gallbladder: 9.4 Group enriched 9 A-431: 27.0;CAPAN-2: 99.3;HaCaT: 22.4;PC-3: 33.9;RPTEC TERT1: 38.6;RT4: 104.1 +ADGRF4 FLJ38076, GPR115, PGR18 ENSG00000153294 Adhesion G protein-coupled receptor F4 6 47685864-47722021 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA007131, HPA007158 Enhanced Uncertain Mitochondria Pancreatic cancer:5.52e-4 (unfavourable) Mixed Group enriched 8 esophagus: 12.1;skin: 45.8 tonsil: 3.7 Cell line enhanced HaCaT: 11.5;HBEC3-KT: 14.9;hTCEpi: 22.8;U-87 MG: 25.8 +FRMD1 bA164L23.1, DKFZp434O0117, FLJ00181, FLJ22615, FLJ40260 ENSG00000153303 FERM domain containing 1 6 168055745-168081557 Predicted intracellular proteins Evidence at protein level HPA030347 Supported Approved Actin filaments Tissue enriched Tissue enhanced colon: 5.8;stomach: 6.4;testis: 5.9 rectum: 4.6 Cell line enhanced K-562: 2.8 +FAM49B BM-009 ENSG00000153310 Family with sequence similarity 49 member B 8 129839593-130017129 Predicted intracellular proteins Evidence at protein level HPA009076 Approved Approved Nucleus
Cytosol Renal cancer:3.09e-10 (unfavourable), Liver cancer:3.02e-6 (unfavourable), Endometrial cancer:1.24e-4 (unfavourable) Expressed in all Expressed in all lymph node: 137.4 Expressed in all +ASAP1 CENTB4, DDEF1, KIAA1249, PAP, ZG14P ENSG00000153317 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 8 130052104-130443660 Predicted intracellular proteins Evidence at protein level HPA011136, CAB037292, HPA048565 Approved Approved Plasma membrane
Centrosome
Cytosol Liver cancer:5.63e-8 (unfavourable), Renal cancer:1.50e-7 (unfavourable), Lung cancer:3.56e-5 (unfavourable), Endometrial cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all testis: 56.0 Expressed in all +TRAPPC8 GSG1, HsT2706, KIAA1012, TRS85 ENSG00000153339 Trafficking protein particle complex 8 18 31829173-31953136 Predicted intracellular proteins Evidence at protein level HPA041107 Approved Approved Microtubules
Cytosol Renal cancer:1.85e-9 (favourable) Expressed in all Expressed in all testis: 54.2 Expressed in all +FAM81B FLJ25333 ENSG00000153347 Family with sequence similarity 81 member B 5 95391344-95450454 Predicted intracellular proteins Evidence at protein level HPA072554 Approved Mixed Group enriched 13 fallopian tube: 78.9;testis: 121.2 parathyroid gland: 7.5 Cell line enhanced CAPAN-2: 1.1 +INO80C C18orf37, FLJ38183, hIes6, IES6 ENSG00000153391 INO80 complex subunit C 18 35452230-35497991 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049060 Approved Supported Nucleoli fibrillar center Endometrial cancer:2.62e-5 (unfavourable), Cervical cancer:3.58e-4 (favourable) Expressed in all Expressed in all testis: 166.3 Expressed in all +LPCAT1 AGPAT10, AGPAT9, AYTL2, FLJ12443 ENSG00000153395 Lysophosphatidylcholine acyltransferase 1 5 1456480-1523977 Enzymes, Predicted membrane proteins Evidence at protein level HPA012501, HPA022268 Enhanced Supported Endoplasmic reticulum
Lipid droplets Liver cancer:1.88e-8 (unfavourable), Renal cancer:2.64e-7 (unfavourable), Pancreatic cancer:4.90e-5 (favourable), Cervical cancer:7.11e-5 (unfavourable), Endometrial cancer:3.67e-4 (unfavourable) Expressed in all Tissue enhanced lung: 19.0;spleen: 14.7 cerebral cortex: 4.4 Cell line enhanced BEWO: 80.0;EFO-21: 74.7;PC-3: 52.0 +PLEKHG4B KIAA1909 ENSG00000153404 Pleckstrin homology and RhoGEF domain containing G4B 5 92151-189972 Predicted intracellular proteins Evidence at protein level HPA036274, HPA058157 Uncertain Approved Nucleoplasm Lung cancer:3.47e-4 (favourable) Mixed Tissue enhanced thyroid gland: 5.2 testis: 3.2 Cell line enhanced REH: 30.0;SCLC-21H: 16.5;T-47d: 17.9 +NMRAL1 FLJ25918, HSCARG, SDR48A1 ENSG00000153406 NmrA like redox sensor 1 16 4461680-4495763 Predicted intracellular proteins Evidence at protein level HPA041353, HPA062287 Uncertain Enhanced Nucleus Cervical cancer:3.33e-7 (favourable) Expressed in all Mixed fallopian tube: 21.5 Mixed +UBALD1 FAM100A ENSG00000153443 UBA like domain containing 1 16 4608883-4615027 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA066771 Approved Approved Nucleus
Cell Junctions
Cytosol Expressed in all Expressed in all cerebral cortex: 23.8 Expressed in all +C16orf89 MGC45438 ENSG00000153446 Chromosome 16 open reading frame 89 16 5044122-5066110 Predicted secreted proteins Evidence at protein level HPA013613, HPA016934 Enhanced Group enriched Tissue enhanced lung: 145.4;thyroid gland: 352.5 epididymis: 94.3 Cell line enhanced ASC diff: 1.4;Hep G2: 1.7;NTERA-2: 1.5;U-2197: 2.0 +TMEM251 C14orf109, DKFZP564F1123 ENSG00000153485 Transmembrane protein 251 14 93184951-93187089 Predicted membrane proteins Evidence at transcript level HPA048559 Uncertain Approved Golgi apparatus
Cell Junctions Liver cancer:6.14e-7 (unfavourable), Renal cancer:1.10e-4 (favourable) Expressed in all Expressed in all prostate: 27.0 Expressed in all +ING1 p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a ENSG00000153487 Inhibitor of growth family member 1 13 110712736-110723339 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016136, CAB017773, HPA052591 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:5.81e-4 (favourable) Expressed in all Expressed in all ovary: 20.9 Expressed in all +TEX29 bA474D23.1, C13orf16, MGC35169 ENSG00000153495 Testis expressed 29 13 111316184-111344249 Predicted membrane proteins Evidence at transcript level Mixed Tissue enriched 15 testis: 46.8 cerebral cortex: 3.0 Cell line enriched 42 U-698: 15.3 +SPACA7 C13orf28 ENSG00000153498 Sperm acrosome associated 7 13 112376319-112434689 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048349 Enhanced Not detected Tissue enriched 73 testis: 50.2 bone marrow,skin: 0.6 Not detected +ADPRHL1 ARH2 ENSG00000153531 ADP-ribosylhydrolase like 1 13 113399610-113453524 Predicted intracellular proteins Evidence at protein level HPA066478 Enhanced Approved Nucleoplasm Liver cancer:2.55e-5 (unfavourable), Head and neck cancer:4.88e-4 (unfavourable) Mixed Group enriched 14 heart muscle: 258.3;skeletal muscle: 114.3 fallopian tube: 13.2 Cell line enhanced SCLC-21H: 24.5;T-47d: 35.4 +CMTM7 CKLFSF7, FLJ30992 ENSG00000153551 CKLF like MARVEL transmembrane domain containing 7 3 32391671-32483067 Predicted membrane proteins, Transporters Evidence at protein level HPA077409 Approved Plasma membrane Renal cancer:1.00e-6 (unfavourable), Liver cancer:3.21e-4 (unfavourable) Expressed in all Mixed fallopian tube: 61.7 Mixed +FBXL2 FBL2, FBL3 ENSG00000153558 F-box and leucine rich repeat protein 2 3 33277025-33403662 Predicted intracellular proteins Evidence at protein level HPA061783 Approved Nucleus
Nucleoli
Plasma membrane Renal cancer:3.35e-4 (favourable) Mixed Mixed cerebral cortex: 5.8 Cell line enhanced CAPAN-2: 6.7 +UBP1 LBP-1a ENSG00000153560 Upstream binding protein 1 (LBP-1a) 3 33388336-33441371 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003967 Supported Nucleoplasm Colorectal cancer:1.81e-4 (favourable), Liver cancer:9.45e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 54.5 Expressed in all +RMND5A FLJ13910, GID2, GID2A, p44CTLH, RMD5 ENSG00000153561 Required for meiotic nuclear division 5 homolog A 2 86720173-86778041 Predicted intracellular proteins Evidence at protein level HPA046795, HPA060843 Uncertain Approved Nucleoplasm Endometrial cancer:3.03e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 39.1 Expressed in all +CD8A CD8 ENSG00000153563 CD8a molecule 2 86784610-86808396 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000012, HPA037756, CAB075722 Enhanced Endometrial cancer:6.15e-6 (favourable), Renal cancer:1.91e-5 (unfavourable), Cervical cancer:4.54e-4 (favourable) Expressed in all Tissue enhanced spleen: 161.9 lymph node: 46.9 Cell line enriched 5 MOLT-4: 11.7 +RPIA ENSG00000153574 Ribose 5-phosphate isomerase A 2 88691644-88750935 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042620 Approved Renal cancer:8.53e-6 (unfavourable), Liver cancer:1.46e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 54.2 Expressed in all +GOLGA8F DKFZp434P162 ENSG00000153684 Golgin A8 family member F 15 28378621-28392018 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 51 testis: 5.1 all non-specific tissues: 0.0 Cell line enriched 14 NB-4: 1.3 +PTPRD HPTP, PTPD ENSG00000153707 Protein tyrosine phosphatase, receptor type D 9 8314246-10612723 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054829 Uncertain Approved Vesicles Renal cancer:7.45e-6 (favourable) Mixed Tissue enhanced cerebral cortex: 32.7;parathyroid gland: 47.0 ovary: 11.7 Cell line enhanced AF22: 27.3;RH-30: 9.9 +LURAP1L bA3L8.2, C9orf150, FLJ38505, MGC46502 ENSG00000153714 Leucine rich adaptor protein 1 like 9 12775021-12822131 Predicted intracellular proteins Evidence at protein level HPA024407 Uncertain Approved Nucleus
Nucleoli Expressed in all Mixed placenta: 43.0 Cell line enhanced HHSteC: 122.7;hTERT-HME1: 91.2;T-47d: 162.8 +CNKSR3 FLJ31349, MAGI1 ENSG00000153721 CNKSR family member 3 6 154387504-154510659 Predicted intracellular proteins Evidence at protein level CAB037133, HPA049651 Approved Approved Mitochondria
Cytosol Renal cancer:6.00e-4 (favourable) Mixed Mixed esophagus: 15.6 Mixed +GTF2E1 FE, TFIIE-A ENSG00000153767 General transcription factor IIE subunit 1 3 120742637-120783069 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009884, HPA056359, HPA066881 Enhanced Enhanced Nucleus
Cytosol Expressed in all Mixed testis: 18.4 Expressed in all +CFDP1 BCNT, CENP-29, CP27, p97, SWC5, Yeti ENSG00000153774 Craniofacial development protein 1 16 75293698-75433485 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041316, HPA048242 Approved Approved Nucleoplasm
Vesicles Head and neck cancer:9.63e-5 (unfavourable) Expressed in all Expressed in all testis: 111.6 Expressed in all +TGIF2LX ENSG00000153779 TGFB induced factor homeobox 2 like, X-linked X 89921882-89922883 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034543 Supported Approved Nucleoplasm Tissue enhanced Tissue enriched 134 testis: 13.3 all non-specific tissues: 0.0 Group enriched 10 SH-SY5Y: 11.2;U-2 OS: 12.7;U-266/84: 14.3 +ZDHHC7 FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370 ENSG00000153786 Zinc finger DHHC-type containing 7 16 84974181-85011535 Enzymes, Predicted membrane proteins Evidence at protein level HPA019215, HPA059054, HPA059642 Uncertain Enhanced Golgi apparatus Renal cancer:1.12e-5 (favourable), Liver cancer:4.20e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 64.8 Expressed in all +FAM92B FLJ44299 ENSG00000153789 Family with sequence similarity 92 member B 16 85098358-85112508 Predicted intracellular proteins Evidence at protein level HPA041022 Enhanced Group enriched Tissue enriched 10 fallopian tube: 136.1 lung: 14.1 Cell line enhanced SCLC-21H: 3.0 +C7orf31 ENSG00000153790 Chromosome 7 open reading frame 31 7 25134697-25180356 Predicted intracellular proteins Evidence at protein level HPA020346 Approved Nucleoplasm
Mitochondria Glioma:1.52e-4 (unfavourable) Expressed in all Tissue enriched 14 testis: 131.4 parathyroid gland: 9.5 Mixed +TMPRSS11D ENSG00000153802 Transmembrane protease, serine 11D 4 67820876-67884032 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052834 Uncertain Group enriched Group enriched 39 esophagus: 70.5;tonsil: 30.6 cervix, uterine: 1.3 Not detected +JAZF1 DKFZp761K2222, TIP27, ZNF802 ENSG00000153814 JAZF zinc finger 1 7 27830573-28180743 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB019271, HPA066967 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all Expressed in all adrenal gland: 112.8 Mixed +CMIP ENSG00000153815 C-Maf inducing protein 16 81445170-81711762 Predicted intracellular proteins Evidence at protein level HPA054424, HPA066710 Approved Supported Nucleoplasm
Cytosol Lung cancer:9.47e-7 (unfavourable), Thyroid cancer:1.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 87.4 Expressed in all +SPHKAP SKIP ENSG00000153820 SPHK1 interactor, AKAP domain containing 2 227979950-228181645 Predicted intracellular proteins Evidence at protein level HPA042499, HPA048168 Enhanced Not detected Group enriched 7 cerebral cortex: 19.4;heart muscle: 19.0 ovary: 2.7 Cell line enriched 17 BJ hTERT+: 37.3 +KCNJ16 BIR9, Kir5.1 ENSG00000153822 Potassium voltage-gated channel subfamily J member 16 17 70053429-70135608 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA059563 Approved Uncertain Vesicles Renal cancer:9.61e-7 (favourable), Thyroid cancer:6.58e-4 (favourable) Group enriched Group enriched 8 kidney: 209.1;parathyroid gland: 269.7;thyroid gland: 235.1 seminal vesicle: 31.5 Cell line enriched 18 RPTEC TERT1: 211.8 +PID1 FLJ20701, NYGGF4 ENSG00000153823 Phosphotyrosine interaction domain containing 1 2 228850526-229271285 Predicted intracellular proteins Evidence at protein level HPA036103 Approved Approved Endoplasmic reticulum Expressed in all Expressed in all cerebral cortex: 67.2 Cell line enhanced hTEC/SVTERT24-B: 86.1;LHCN-M2: 48.1;REH: 56.9;RH-30: 88.5 +TRIP12 KIAA0045 ENSG00000153827 Thyroid hormone receptor interactor 12 2 229763838-229923239 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036835, HPA045893 Enhanced Approved Nuclear speckles Liver cancer:3.60e-4 (unfavourable) Expressed in all Expressed in all testis: 270.8 Expressed in all +FBXO36 Fbx36, FLJ37592 ENSG00000153832 F-box protein 36 2 229922302-230013109 Predicted intracellular proteins Evidence at transcript level HPA053865 Approved Nucleus
Nucleoli Endometrial cancer:2.28e-4 (favourable) Expressed in all Tissue enhanced fallopian tube: 17.6 thyroid gland: 12.5 Mixed +CEBPG GPE1BP, IG/EBP-1 ENSG00000153879 CCAAT/enhancer binding protein gamma 19 33373330-33382686 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA012024 Enhanced Supported Nucleoplasm Endometrial cancer:7.97e-5 (unfavourable), Renal cancer:7.23e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 41.3 Expressed in all +KCTD15 MGC25497 ENSG00000153885 Potassium channel tetramerization domain containing 15 19 33795933-33815763 Predicted intracellular proteins Evidence at protein level HPA050822 Uncertain Approved Nucleoplasm
Golgi apparatus Renal cancer:3.65e-8 (unfavourable) Expressed in all Expressed in all skin: 86.3 Mixed +ZNF599 FLJ30663 ENSG00000153896 Zinc finger protein 599 19 34758076-34773229 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA014701 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Mixed Mixed epididymis: 14.6 Mixed +MCOLN2 FLJ36691, TRP-ML2, TRPML2 ENSG00000153898 Mucolipin 2 1 84925583-84997113 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA019114, HPA048999 Uncertain Supported Intermediate filaments Lung cancer:2.56e-4 (favourable) Mixed Mixed rectum: 17.2 Cell line enhanced Daudi: 14.8;HAP1: 14.9;HDLM-2: 23.0;THP-1: 19.8;U-698: 12.6 +LGI4 ENSG00000153902 Leucine rich repeat LGI family member 4 19 35124513-35142451 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042116, HPA043556 Approved Approved Golgi apparatus Renal cancer:2.84e-7 (unfavourable) Group enriched Mixed cerebral cortex: 26.2 Cell line enriched 36 WM-115: 29.6 +DDAH1 DDAH ENSG00000153904 Dimethylarginine dimethylaminohydrolase 1 1 85318481-85578363 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006308 Enhanced Approved Nucleoli
Plasma membrane
Cytosol Renal cancer:5.21e-6 (favourable), Colorectal cancer:5.99e-4 (favourable) Expressed in all Mixed kidney: 121.4 Cell line enhanced SH-SY5Y: 122.6 +SREK1 DKFZp564B176, SFRS12, SRrp508, SRrp86 ENSG00000153914 Splicing regulatory glutamic acid and lysine rich protein 1 5 66139971-66183615 Predicted intracellular proteins Evidence at protein level HPA037673, HPA037674, HPA059332 Enhanced Enhanced Nucleoplasm
Nuclear speckles Head and neck cancer:2.54e-4 (favourable), Renal cancer:5.77e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 15.0 Expressed in all +CHD1 ENSG00000153922 Chromodomain helicase DNA binding protein 1 5 98853985-98928957 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA022236 Approved Supported Nucleus
Nucleoli fibrillar center Renal cancer:7.25e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 44.3 Expressed in all +ANKFN1 FLJ38335 ENSG00000153930 Ankyrin repeat and fibronectin type III domain containing 1 17 55882301-56511659 Predicted intracellular proteins Evidence at protein level HPA021566, HPA022538 Uncertain Mixed Tissue enhanced cervix, uterine: 14.3;fallopian tube: 8.5 cerebral cortex,testis: 3.2 Cell line enhanced HeLa: 4.8;MOLT-4: 12.3;T-47d: 4.7;U-2197: 4.5 +DGKE DAGK6, DGK ENSG00000153933 Diacylglycerol kinase epsilon 17 56834099-56869567 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017167 Approved Approved Nucleus
Cytosol Endometrial cancer:3.92e-5 (favourable) Mixed Mixed testis: 12.1 Cell line enhanced Karpas-707: 61.4 +HS2ST1 KIAA0448 ENSG00000153936 Heparan sulfate 2-O-sulfotransferase 1 1 86914648-87109998 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043069, HPA043603, HPA075001 Supported Approved Mitochondria Liver cancer:6.88e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 34.0 Expressed in all +MSI2 ENSG00000153944 Musashi RNA binding protein 2 17 57255851-57684685 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB022300 Approved Supported Cytosol Renal cancer:9.22e-8 (favourable), Stomach cancer:2.00e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 119.2 Expressed in all +CACNA2D1 CACNA2, CACNL2A, LINC01112, lncRNA-N3, MHS3 ENSG00000153956 Calcium voltage-gated channel auxiliary subunit alpha2delta 1 7 81946444-82443798 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA008213, HPA008621 Enhanced Renal cancer:1.16e-4 (unfavourable) Mixed Mixed cerebral cortex: 35.4 Cell line enhanced HUVEC TERT2: 45.6;SH-SY5Y: 66.1 +ZUFSP C6orf113, dJ412I7.3 ENSG00000153975 Zinc finger with UFM1 specific peptidase domain 6 116635618-116668794 Predicted intracellular proteins Evidence at protein level HPA044426 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:2.11e-4 (unfavourable) Expressed in all Mixed testis: 10.8 Expressed in all +HS3ST3A1 30ST3A1, 3OST3A1 ENSG00000153976 Heparan sulfate-glucosamine 3-sulfotransferase 3A1 17 13495689-13601927 Enzymes, Predicted intracellular proteins Evidence at protein level HPA062518, HPA071530 Uncertain Approved Microtubules Mixed Tissue enhanced spleen: 9.1 seminal vesicle: 6.8 Cell line enhanced PC-3: 40.6;U-251 MG: 103.1;U-87 MG: 72.4 +GDPD1 FLJ37451, GDE4 ENSG00000153982 Glycerophosphodiester phosphodiesterase domain containing 1 17 59220467-59275967 Predicted membrane proteins Evidence at protein level Lung cancer:2.98e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 27.9 testis: 20.0 Cell line enhanced HEL: 27.1;SCLC-21H: 21.6 +NUS1 C6orf68, MGC7199, NgBR, TANGO14 ENSG00000153989 NUS1 dehydrodolichyl diphosphate synthase subunit 6 117675502-117710640 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA027504 Supported Approved Vesicles
Plasma membrane Cervical cancer:6.99e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 92.2 Expressed in all +SEMA3D coll-2, Sema-Z2 ENSG00000153993 Semaphorin 3D 7 84995553-85186855 Predicted intracellular proteins Evidence at protein level HPA037522 Uncertain Approved Golgi apparatus
Plasma membrane Mixed Group enriched 5 spleen: 66.2;thyroid gland: 76.6 prostate: 13.4 Cell line enhanced fHDF/TERT166: 22.0;HaCaT: 25.4;TIME: 36.0 +PPP2R5E ENSG00000154001 Protein phosphatase 2 regulatory subunit B'epsilon 14 63371357-63543374 Predicted intracellular proteins Evidence at protein level HPA006034, CAB072342 Approved Supported Cytosol Liver cancer:1.95e-4 (unfavourable), Renal cancer:4.16e-4 (favourable) Expressed in all Expressed in all thyroid gland: 33.9 Expressed in all +ASB17 ENSG00000154007 Ankyrin repeat and SOCS box containing 17 1 75918873-75932431 Plasma proteins, Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 380 testis: 84.7 kidney: 0.2 Not detected +GRAP ENSG00000154016 GRB2-related adaptor protein 17 19020673-19047637 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046595, HPA066654 Uncertain Approved Centrosome Mixed Tissue enhanced lymph node: 30.9;spleen: 25.4 tonsil: 20.7 Group enriched 5 Daudi: 52.5;HUVEC TERT2: 24.8;MOLT-4: 12.3;REH: 35.4;TIME: 47.9;U-698: 35.4 +SLC5A10 SGLT5 ENSG00000154025 Solute carrier family 5 member 10 17 18950345-19022595 Predicted membrane proteins, Transporters Evidence at protein level HPA052014 Uncertain Tissue enriched Tissue enriched 25 kidney: 43.9 bone marrow: 1.7 Cell line enhanced U-937: 4.4 +AK5 ENSG00000154027 Adenylate kinase 5 1 77282051-77559969 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019128, HPA057255 Enhanced Supported Microtubule organizing center
Cytosol Prostate cancer:3.88e-4 (favourable) Group enriched Tissue enriched 9 cerebral cortex: 220.7 breast: 23.6 Cell line enhanced ASC TERT1: 65.9;BJ: 57.0;fHDF/TERT166: 60.0;LHCN-M2: 159.8;U-2 OS: 61.3 +CABYR CBP86, CT88, FSP-2 ENSG00000154040 Calcium binding tyrosine phosphorylation regulated 18 24138956-24161603 Predicted intracellular proteins Evidence at protein level HPA040703, HPA047801 Enhanced Supported Nucleus
Cytosol Liver cancer:4.75e-4 (unfavourable) Mixed Tissue enriched 39 testis: 445.1 cerebral cortex: 11.3 Cell line enhanced SiHa: 25.8 +IMPACT RWDD5 ENSG00000154059 Impact RWD domain protein 18 24426616-24453535 Predicted intracellular proteins Evidence at protein level HPA041045, HPA041968 Approved Approved Nucleoplasm Renal cancer:7.90e-4 (favourable) Expressed in all Expressed in all testis: 65.0 Mixed +ANKRD29 FLJ25053 ENSG00000154065 Ankyrin repeat domain 29 18 23598926-23662885 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041272, HPA049419 Uncertain Approved Nucleoplasm
Nuclear bodies Head and neck cancer:1.92e-5 (favourable), Lung cancer:5.98e-5 (favourable), Renal cancer:7.20e-5 (favourable) Mixed Mixed lung: 47.4 Cell line enhanced U-2197: 19.0;U-87 MG: 20.5 +SDHAF4 C6orf57, Sdh8 ENSG00000154079 Succinate dehydrogenase complex assembly factor 4 6 70566917-70589569 Predicted secreted proteins Evidence at protein level HPA031824 Supported Approved Nucleus
Mitochondria Renal cancer:1.95e-5 (favourable) Expressed in all Expressed in all fallopian tube: 17.2 Expressed in all +CHST9 GALNAC-4-ST2, GALNAC4ST-2 ENSG00000154080 Carbohydrate sulfotransferase 9 18 26906481-27185317 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011393 Uncertain Mixed Tissue enhanced fallopian tube: 16.5;testis: 12.7 spleen: 7.8 Group enriched 7 CACO-2: 7.6;Hep G2: 9.4;RPTEC TERT1: 31.6;SCLC-21H: 10.6 +THY1 CD90 ENSG00000154096 Thy-1 cell surface antigen 11 119417378-119424985 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003733, CAB068243, CAB068244 Enhanced Approved Nucleus
Plasma membrane Renal cancer:2.40e-6 (unfavourable), Glioma:9.64e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 421.8;smooth muscle: 434.2 gallbladder: 161.0 Cell line enhanced BJ: 643.3;BJ hTERT+: 686.4;fHDF/TERT166: 1040.5 +DNAAF1 CILD13, FLJ25330, LRRC50, ODA7, swt ENSG00000154099 Dynein axonemal assembly factor 1 16 84145287-84178767 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041166, HPA074239 Enhanced Approved Nuclear speckles
Plasma membrane
Cytosol Endometrial cancer:2.14e-4 (favourable) Tissue enhanced Group enriched 19 fallopian tube: 36.3;testis: 82.6 lung: 3.0 Cell line enhanced Hep G2: 1.4;Karpas-707: 3.6;PC-3: 1.4;U-266/70: 3.1;U-266/84: 2.0 +C16orf74 MGC17624 ENSG00000154102 Chromosome 16 open reading frame 74 16 85690084-85751129 Predicted intracellular proteins Evidence at protein level HPA049367 Uncertain Approved Plasma membrane
Centrosome Pancreatic cancer:1.54e-5 (unfavourable), Head and neck cancer:1.71e-4 (unfavourable), Melanoma:4.08e-4 (unfavourable) Mixed Mixed urinary bladder: 13.3 Cell line enhanced HBEC3-KT: 68.8;T-47d: 79.3 +TBCEL LRRC35, MGC10233 ENSG00000154114 Tubulin folding cofactor E like 11 121024072-121090775 Predicted intracellular proteins Evidence at protein level HPA038593, HPA038594 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 35.7 Mixed +JPH3 CAGL237, HDL2, JP-3, JP3, TNRC22 ENSG00000154118 Junctophilin 3 16 87601835-87698156 Disease related genes, Predicted membrane proteins Evidence at protein level HPA076304 Approved Nucleoplasm
Cytosol Mixed Tissue enriched 22 cerebral cortex: 43.3 adrenal gland: 2.0 Cell line enhanced MCF7: 5.8;NTERA-2: 6.6;SH-SY5Y: 8.9;SiHa: 5.9;U-2 OS: 27.3 +ANKH ANK, CCAL2, CMDJ, CPPDD, HANK ENSG00000154122 ANKH inorganic pyrophosphate transport regulator 5 14704804-14871778 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA068104 Approved Cytosol Glioma:7.64e-4 (unfavourable) Expressed in all Expressed in all prostate: 49.4 Mixed +OTULIN FAM105B, FLJ34884 ENSG00000154124 OTU deubiquitinase with linear linkage specificity 5 14664664-14699711 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA051074 Uncertain Approved Plasma membrane
Mitochondria Renal cancer:2.59e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 17.1 Expressed in all +UBASH3B KIAA1959, STS-1, TULA2 ENSG00000154127 Ubiquitin associated and SH3 domain containing B 11 122655675-122814473 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038605, HPA038607 Approved Approved Plasma membrane Mixed Tissue enhanced placenta: 19.6;spleen: 21.3 lung: 6.7 Cell line enhanced HEL: 108.5;HMC-1: 77.6 +ROBO4 ECSM4, FLJ20798, MRB ENSG00000154133 Roundabout guidance receptor 4 11 124883691-124898500 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA065212 Approved Plasma membrane Liver cancer:4.85e-4 (favourable), Stomach cancer:8.73e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 58.2 adipose tissue: 45.1 Group enriched 9 HUVEC TERT2: 203.4;TIME: 180.3 +ROBO3 FLJ21044, HGPPS, HGPS, RBIG1 ENSG00000154134 Roundabout guidance receptor 3 11 124865386-124881470 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced smooth muscle: 1.2 cerebral cortex: 0.8 Cell line enriched 11 AF22: 17.9 +PANX3 Px3 ENSG00000154143 Pannexin 3 11 124611490-124620356 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Not detected testis: 0.4 Not detected +TBRG1 FLJ14621, NIAM, TB-5 ENSG00000154144 Transforming growth factor beta regulator 1 11 124622836-124635398 Predicted intracellular proteins Evidence at protein level HPA055645, HPA068022 Enhanced Nucleus Expressed in all Expressed in all spleen: 16.0 Expressed in all +NRGN RC3 ENSG00000154146 Neurogranin 11 124739846-124747210 Predicted intracellular proteins Evidence at protein level CAB006908, HPA038171 Enhanced Renal cancer:1.52e-5 (unfavourable) Expressed in all Tissue enriched 17 cerebral cortex: 961.5 lung: 56.2 Cell line enhanced HEL: 133.6;PC-3: 108.8 +FAM134B FLJ20152, JK1 ENSG00000154153 Family with sequence similarity 134 member B 5 16473038-16617058 Disease related genes, Predicted membrane proteins Evidence at protein level HPA012077 Supported Endoplasmic reticulum Renal cancer:5.25e-10 (favourable) Expressed in all Expressed in all kidney: 62.2 Cell line enhanced HSkMC: 20.3;RPTEC TERT1: 19.9;SCLC-21H: 20.1 +CDH12 Br-cadherin, CDHB ENSG00000154162 Cadherin 12 5 21750673-22853622 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA029325 Uncertain Approved Vesicles Mixed Tissue enhanced cerebral cortex: 3.6;cervix, uterine: 4.5;fallopian tube: 3.5 adrenal gland: 2.2 Group enriched 5 PC-3: 2.0;SCLC-21H: 3.7;U-2 OS: 1.3 +GPR15 ENSG00000154165 G protein-coupled receptor 15 3 98531899-98533150 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA013775 Approved Mixed Tissue enhanced colon: 25.0;rectum: 46.8 urinary bladder: 18.4 Group enriched 22 HDLM-2: 5.6;U-266/70: 1.9 +TOMM70 KIAA0719, Tom70, TOMM70A ENSG00000154174 Translocase of outer mitochondrial membrane 70 3 100363431-100401398 Predicted membrane proteins Evidence at protein level HPA014589, CAB017156, HPA048020 Enhanced Enhanced Mitochondria Expressed in all Expressed in all cerebral cortex: 52.8 Expressed in all +ABI3BP DKFZP586L2024, NESHBP, TARSH ENSG00000154175 ABI family member 3 binding protein 3 100749156-100993515 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044127 Uncertain Renal cancer:6.14e-4 (favourable) Mixed Mixed gallbladder: 158.4 Cell line enhanced hTEC/SVTERT24-B: 841.3;hTERT-HME1: 650.5;TIME: 1525.7 +ANGPT1 Ang1, KIAA0003 ENSG00000154188 Angiopoietin 1 8 107249482-107498055 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB017815, HPA018793, HPA018816 Enhanced Renal cancer:4.40e-4 (favourable) Mixed Tissue enhanced seminal vesicle: 46.2 lung: 32.9 Cell line enhanced ASC diff: 60.0;HEL: 46.9;HSkMC: 105.6;U-138 MG: 70.1;WM-115: 46.8 +PITPNC1 RDGB-BETA, RDGBB, RDGBB1 ENSG00000154217 Phosphatidylinositol transfer protein, cytoplasmic 1 17 67377281-67697261 Predicted intracellular proteins Evidence at protein level HPA026563, HPA031250 Uncertain Approved Nucleoplasm
Cytosol Head and neck cancer:4.85e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 46.6 Mixed +CC2D1B KIAA1836 ENSG00000154222 Coiled-coil and C2 domain containing 1B 1 52345723-52366193 Predicted intracellular proteins Evidence at protein level HPA027500, HPA031426 Uncertain Supported Nucleoplasm
Vesicles Liver cancer:1.45e-5 (unfavourable) Expressed in all Expressed in all lung: 18.7 Expressed in all +CERS3 LASS3, MGC27091 ENSG00000154227 Ceramide synthase 3 15 100400395-100544995 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006092, HPA024356 Approved Approved Nucleoplasm Tissue enhanced Group enriched 9 esophagus: 48.1;skin: 60.5;testis: 32.3;tonsil: 14.3 breast: 4.3 Cell line enriched 6 hTCEpi: 47.1 +PRKCA PKCA ENSG00000154229 Protein kinase C alpha 17 66302636-66810743 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB003844, HPA006563, HPA006564, CAB016290 Enhanced Approved Enhanced Plasma membrane
Cytosol Expressed in all Mixed cerebral cortex: 45.0 Cell line enhanced U-87 MG: 157.3 +LRRK1 FLJ23119, KIAA1790, RIPK6, Roco1 ENSG00000154237 Leucine rich repeat kinase 1 15 100919215-101078254 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010537 Uncertain Supported Mitochondria
Cytosol Renal cancer:5.71e-5 (unfavourable) Mixed Mixed lymph node: 12.6 Cell line enhanced Daudi: 27.9 +CEP112 CCDC46, MGC33887 ENSG00000154240 Centrosomal protein 112 17 65635538-66192084 Predicted intracellular proteins Evidence at protein level HPA024481 Approved Nucleoplasm
Golgi apparatus Expressed in all Tissue enriched 6 testis: 86.4 endometrium: 14.2 Cell line enhanced LHCN-M2: 27.2;RH-30: 73.5 +GAL3ST2 GP3ST ENSG00000154252 Galactose-3-O-sulfotransferase 2 2 241776825-241804208 Predicted secreted proteins Evidence at protein level HPA071809 Enhanced Group enriched Group enriched 8 colon: 9.3;rectum: 4.0 appendix,fallopian tube: 0.8 Cell line enhanced Hep G2: 1.4 +ABCA9 EST640918 ENSG00000154258 ATP binding cassette subfamily A member 9 17 68974488-69061064 Predicted membrane proteins, Transporters Evidence at protein level HPA052113, HPA054823 Uncertain Approved Endoplasmic reticulum Mixed Mixed ovary: 32.5 Cell line enhanced ASC diff: 14.7;ASC TERT1: 31.9;HSkMC: 11.9 +ABCA6 EST155051 ENSG00000154262 ATP binding cassette subfamily A member 6 17 69078702-69141888 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA064878, HPA067180 Approved Nucleoplasm Liver cancer:3.29e-4 (favourable) Tissue enriched Tissue enhanced liver: 41.4 ovary: 37.4 Cell line enhanced ASC diff: 28.1;ASC TERT1: 41.4;HSkMC: 18.8;HUVEC TERT2: 47.8 +ABCA10 EST698739 ENSG00000154263 ATP binding cassette subfamily A member 10 17 69147214-69244846 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014535 Uncertain Mixed Mixed ovary: 13.8 Cell line enhanced HUVEC TERT2: 1.1;RT4: 1.0;U-2197: 1.8 +ABCA5 EST90625 ENSG00000154265 ATP binding cassette subfamily A member 5 17 69244311-69327244 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA022032, HPA062904 Approved Approved Nucleus Pancreatic cancer:9.97e-5 (favourable) Expressed in all Expressed in all skin: 28.0 Cell line enhanced SiHa: 19.6 +ENPP3 B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3 ENSG00000154269 Ectonucleotide pyrophosphatase/phosphodiesterase 3 6 131628442-131747418 CD markers, Enzymes, Predicted intracellular proteins Evidence at protein level HPA043772 Enhanced Renal cancer:1.96e-4 (unfavourable) Tissue enriched Tissue enhanced cervix, uterine: 45.4;small intestine: 49.9 seminal vesicle: 22.0 Group enriched 15 HEL: 3.9;Hep G2: 9.9;HMC-1: 5.4 +C4orf19 FLJ11017 ENSG00000154274 Chromosome 4 open reading frame 19 4 37453941-37623495 Predicted intracellular proteins Evidence at protein level HPA043458, HPA052894 Enhanced Supported Cell Junctions Renal cancer:1.49e-11 (favourable) Mixed Mixed rectum: 26.9 Group enriched 6 RT4: 70.0;SK-BR-3: 25.9;T-47d: 116.1 +UCHL1 PARK5, PGP9.5, Uch-L1 ENSG00000154277 Ubiquitin C-terminal hydrolase L1 4 41256413-41268455 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB002580, HPA005993, CAB079024 Enhanced Supported Enhanced Nucleoplasm
Cytosol Endometrial cancer:4.08e-5 (unfavourable), Urothelial cancer:1.93e-4 (unfavourable) Expressed in all Tissue enriched 7 cerebral cortex: 785.9 adrenal gland: 107.9 Cell line enhanced EFO-21: 912.4;SCLC-21H: 1141.2;U-87 MG: 916.2 +MIA3 FLJ39207, KIAA0268, TANGO, TANGO1, UNQ6077 ENSG00000154305 MIA family member 3, ER export factor 1 222618086-222668012 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055922, HPA056816 Enhanced Enhanced Vesicles Renal cancer:3.73e-4 (unfavourable) Expressed in all Expressed in all testis: 81.5 Expressed in all +DISP1 DISPA, DKFZP434I0428, MGC13130, MGC16796 ENSG00000154309 Dispatched RND transporter family member 1 1 222872271-223005995 Predicted membrane proteins Evidence at protein level HPA051411 Uncertain Approved Nuclear bodies Renal cancer:3.86e-5 (favourable), Thyroid cancer:4.16e-4 (favourable), Pancreatic cancer:5.00e-4 (favourable) Expressed in all Mixed lung: 15.8 Cell line enhanced RH-30: 15.5 +TNIK KIAA0551 ENSG00000154310 TRAF2 and NCK interacting kinase 3 171061339-171460408 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA012128, HPA012297 Approved Supported Nucleoplasm
Cytosol Expressed in all Mixed cerebral cortex: 35.5 Cell line enhanced HEL: 58.9;HMC-1: 63.1;WM-115: 53.8 +FAM167A C8orf13 ENSG00000154319 Family with sequence similarity 167 member A 8 11421463-11474715 Predicted intracellular proteins Evidence at protein level HPA023915, HPA030426 Approved Approved Mitochondria Endometrial cancer:5.96e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 32.4;thyroid gland: 88.0 lung: 15.8 Cell line enhanced Daudi: 41.5;RPMI-8226: 43.0;SH-SY5Y: 48.2 +NEIL2 FLJ31644, MGC2832, MGC4505, NEH2 ENSG00000154328 Nei like DNA glycosylase 2 8 11769639-11787346 Enzymes, Predicted intracellular proteins Evidence at protein level HPA073029, HPA073916 Enhanced Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 45.4 Mixed +PGM5 PGMRP ENSG00000154330 Phosphoglucomutase 5 9 68328308-68531061 Predicted intracellular proteins Evidence at protein level CAB034397, HPA046329, HPA067102 Enhanced Renal cancer:1.83e-5 (favourable) Tissue enhanced Tissue enhanced prostate: 283.6;seminal vesicle: 327.6 smooth muscle: 217.9 Cell line enhanced PC-3: 55.9;RH-30: 40.1;SK-BR-3: 38.8 +WNT3A ENSG00000154342 Wnt family member 3A 1 228007051-228061260 Predicted secreted proteins Evidence at protein level Cervical cancer:6.11e-5 (favourable) Mixed Tissue enriched 6 placenta: 23.2 lung: 3.8 Group enriched 9 HEK 293: 1.1;U-2 OS: 3.9 +OBSCN ARHGEF30, KIAA1556, KIAA1639, UNC89 ENSG00000154358 Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 1 228208130-228378874 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021186 Enhanced Approved Plasma membrane
Cytosol Endometrial cancer:1.64e-4 (unfavourable) Mixed Tissue enriched 7 skeletal muscle: 301.1 heart muscle: 45.7 Mixed +LONRF1 FLJ23749, RNF191 ENSG00000154359 LON peptidase N-terminal domain and ring finger 1 8 12721894-12756073 Predicted intracellular proteins Evidence at protein level HPA023584, HPA024814 Uncertain Approved Plasma membrane
Centrosome
Cytosol Expressed in all Expressed in all skin: 30.8 Cell line enhanced Karpas-707: 47.8;SCLC-21H: 45.0 +TRIM11 BIA1, RNF92 ENSG00000154370 Tripartite motif containing 11 1 228393673-228406840 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028541, HPA043879 Approved Enhanced Nucleus
Cytosol Liver cancer:7.42e-5 (unfavourable), Renal cancer:1.62e-4 (unfavourable) Expressed in all Mixed bone marrow: 18.8 Expressed in all +ENAH FLJ10773, MENA, NDPP1 ENSG00000154380 Enabled homolog (Drosophila) 1 225486835-225653142 Predicted intracellular proteins Evidence at protein level HPA028448, HPA028696 Enhanced Enhanced Plasma membrane
Focal adhesion sites
Cytosol Expressed in all Mixed smooth muscle: 81.3 Mixed +PPP1R3A GM, PPP1R3 ENSG00000154415 Protein phosphatase 1 regulatory subunit 3A 7 113876777-114075920 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Not detected Group enriched 18 heart muscle: 26.6;skeletal muscle: 53.1 prostate: 2.2 Cell line enriched 59 THP-1: 9.8 +CCSAP C1orf96, CSAP, FLJ41471 ENSG00000154429 Centriole, cilia and spindle associated protein 1 229321005-229343294 Predicted intracellular proteins Evidence at protein level HPA028402, HPA043443 Enhanced Supported Nucleus
Plasma membrane
Microtubule ends Renal cancer:4.50e-13 (unfavourable), Liver cancer:1.41e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 54.0 placenta: 18.6 Expressed in all +ASZ1 ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3 ENSG00000154438 Ankyrin repeat, SAM and basic leucine zipper domain containing 1 7 117363222-117428123 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020558 Enhanced Approved Nucleoplasm
Cytosol Not detected Tissue enriched 188 testis: 18.7 all non-specific tissues: 0.0 Not detected +SH3RF1 KIAA1494, POSH, RNF142, SH3MD2 ENSG00000154447 SH3 domain containing ring finger 1 4 169094256-169271105 Enzymes, Predicted intracellular proteins Evidence at protein level HPA074783 Supported Vesicles
Intermediate filaments Renal cancer:5.51e-8 (favourable) Expressed in all Expressed in all thyroid gland: 32.1 Mixed +GBP5 ENSG00000154451 Guanylate binding protein 5 1 89258950-89272804 Predicted intracellular proteins Evidence at protein level HPA028656 Approved Approved Endoplasmic reticulum Renal cancer:5.53e-8 (unfavourable), Endometrial cancer:3.73e-6 (favourable), Ovarian cancer:1.24e-4 (favourable), Colorectal cancer:9.54e-4 (favourable) Expressed in all Tissue enhanced appendix: 100.5 lymph node: 60.4 Cell line enhanced NB-4: 6.3;U-266/70: 15.8;U-937: 24.8 +BUB3 BUB3L ENSG00000154473 BUB3, mitotic checkpoint protein 10 123154277-123170467 Predicted intracellular proteins Evidence at protein level HPA003601, CAB037075 Supported Enhanced Nucleoplasm Renal cancer:3.81e-7 (unfavourable), Liver cancer:4.45e-5 (unfavourable), Cervical cancer:2.04e-4 (favourable) Expressed in all Expressed in all lymph node: 112.0 Expressed in all +GPR26 ENSG00000154478 G protein-coupled receptor 26 10 123666355-123694607 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA062736 Enhanced Tissue enriched Tissue enriched 16 cerebral cortex: 4.3 testis: 0.2 Cell line enriched 15 SCLC-21H: 1.4 +CCDC173 C2orf77, LOC129881 ENSG00000154479 Coiled-coil domain containing 173 2 169645425-169694433 Predicted intracellular proteins Evidence at protein level HPA042995, HPA048454 Uncertain Mixed Tissue enriched 6 testis: 143.7 fallopian tube: 23.4 Cell line enhanced HEL: 9.8;SCLC-21H: 3.1 +MMP21 ENSG00000154485 Matrix metallopeptidase 21 10 125766453-125775821 Disease related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 27 epididymis: 59.2 ovary: 2.1 Not detected +C10orf90 bA422P15.2, FATS, FLJ32938 ENSG00000154493 Chromosome 10 open reading frame 90 10 126424997-126670446 Predicted intracellular proteins Evidence at protein level HPA038648, HPA057599 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Tissue enriched Group enriched 12 breast: 5.6;cerebral cortex: 15.3;salivary gland: 4.3;testis: 12.1 adipose tissue,skin: 0.7 Group enriched 9 SK-MEL-30: 94.3;U-2197: 33.5;U-266/84: 18.9;U-87 MG: 36.2;WM-115: 29.4 +FAM69A FLJ23493 ENSG00000154511 Family with sequence similarity 69 member A 1 92832737-92961522 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015718, HPA017281 Approved Approved Nucleus
Cytosol Renal cancer:1.45e-7 (unfavourable), Breast cancer:8.96e-4 (favourable) Expressed in all Mixed cerebral cortex: 44.7 Mixed +ATP5G3 ENSG00000154518 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 175176258-175184607 Predicted membrane proteins Evidence at transcript level Renal cancer:2.31e-6 (favourable), Head and neck cancer:6.01e-4 (unfavourable), Colorectal cancer:9.90e-4 (favourable) Expressed in all Expressed in all heart muscle: 534.0 Expressed in all +CNTNAP3B ENSG00000154529 Contactin associated protein-like 3B 9 41890314-42129510 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA047731 Uncertain Not detected Mixed esophagus,skin: 10.4 Cell line enhanced A549: 27.0;AF22: 41.2;WM-115: 28.0 +MAGED4 KIAA1859, MAGE-E1, MAGE1, MGC3210 ENSG00000154545 MAGE family member D4 X 52184823-52192268 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003554 Uncertain Not detected Not detected cerebral cortex: 0.7 Cell line enhanced A549: 2.7;ASC TERT1: 1.8;Hep G2: 5.3 +SRSF12 SFRS13B, SFRS19, SRrp35 ENSG00000154548 Serine and arginine rich splicing factor 12 6 89095959-89118081 Predicted intracellular proteins Evidence at protein level HPA049782 Approved Mixed Group enriched 6 cerebral cortex: 6.9;testis: 20.9 parathyroid gland,thyroid gland: 2.1 Cell line enhanced AF22: 9.1;AN3-CA: 8.8;HAP1: 7.7;HEK 293: 7.0;REH: 6.9;SCLC-21H: 9.5;SH-SY5Y: 8.4 +PDLIM3 ALP ENSG00000154553 PDZ and LIM domain 3 4 185500660-185535612 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004749 Enhanced Renal cancer:4.97e-7 (unfavourable), Thyroid cancer:2.13e-6 (unfavourable), Liver cancer:7.22e-4 (unfavourable) Expressed in all Tissue enhanced skeletal muscle: 1097.6 seminal vesicle: 292.1 Cell line enhanced LHCN-M2: 125.9;RH-30: 35.3;U-266/70: 91.6 +SORBS2 ARGBP2, KIAA0777 ENSG00000154556 Sorbin and SH3 domain containing 2 4 185585444-185956652 Predicted intracellular proteins Evidence at protein level HPA036754, HPA036755 Supported Supported Nucleoplasm Renal cancer:3.10e-6 (favourable), Liver cancer:1.47e-5 (favourable), Endometrial cancer:6.07e-5 (favourable) Expressed in all Tissue enhanced heart muscle: 378.9;thyroid gland: 462.8 parathyroid gland: 282.5 Cell line enhanced AF22: 235.7;TIME: 107.2;WM-115: 71.3 +ELOC SIII, TCEB1 ENSG00000154582 Elongin C 8 73939169-73972287 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA078113 Approved Cell Junctions Breast cancer:6.48e-4 (unfavourable) Expressed in all Expressed in all testis: 162.4 Expressed in all +LY96 MD-2 ENSG00000154589 Lymphocyte antigen 96 8 73991352-74029087 Predicted secreted proteins Evidence at protein level HPA053060 Approved Vesicles Renal cancer:6.38e-11 (unfavourable) Expressed in all Mixed spleen: 61.2 Cell line enhanced Karpas-707: 119.4;U-87 MG: 82.4 +PSMA8 MGC26605, PSMA7L ENSG00000154611 Proteasome subunit alpha 8 18 26133852-26193355 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 20 testis: 39.0 lymph node,tonsil: 1.9 Group enriched 73 Daudi: 24.2;U-266/70: 15.3;U-266/84: 15.8 +TMSB4Y TB4Y ENSG00000154620 Thymosin beta 4, Y-linked Y 13703567-13706024 Predicted intracellular proteins Evidence at protein level Mixed Mixed testis: 5.7 Cell line enhanced BEWO: 13.6;HEL: 10.6;RPTEC TERT1: 13.5;SCLC-21H: 6.1 +CXADR CAR ENSG00000154639 Coxsackie virus and adenovirus receptor 21 17512382-17593579 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003342, CAB005103, HPA030411, HPA030412 Enhanced Enhanced Plasma membrane
Cell Junctions Head and neck cancer:3.50e-4 (favourable) Expressed in all Mixed skin: 59.1 Cell line enhanced CACO-2: 77.2;NTERA-2: 105.2;RT4: 82.7 +BTG3 ANA, APRO4, tob55 ENSG00000154640 BTG anti-proliferation factor 3 21 17593653-17612947 Predicted intracellular proteins Evidence at protein level HPA018400 Approved Liver cancer:1.16e-4 (unfavourable), Renal cancer:7.37e-4 (unfavourable) Expressed in all Mixed epididymis: 129.1 Mixed +C21orf91 C21orf14, C21orf38, CSSG1, EURL, YG81 ENSG00000154642 Chromosome 21 open reading frame 91 21 17788967-17819386 Predicted intracellular proteins Evidence at protein level HPA018288, HPA049030 Approved Approved Microtubules
Cytokinetic bridge Expressed in all Mixed testis: 44.4 Cell line enhanced Karpas-707: 77.6 +CHODL C21orf68, FLJ12627, MT75, PRED12 ENSG00000154645 Chondrolectin 21 17901263-18267373 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017282 Enhanced Supported Endometrial cancer:1.18e-6 (unfavourable) Mixed Tissue enhanced spleen: 19.5;testis: 57.6 prostate: 9.3 Cell line enhanced U-266/70: 2.1;U-266/84: 5.1;U-87 MG: 7.6 +TMPRSS15 ENTK, MGC133046, PRSS7 ENSG00000154646 Transmembrane protease, serine 15 21 18269116-18485879 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015611, HPA072934 Enhanced Group enriched Tissue enriched 44 duodenum: 1010.9 small intestine: 22.7 Group enriched 22 U-138 MG: 50.9;U-87 MG: 140.8 +NCAM2 MGC51008, NCAM21 ENSG00000154654 Neural cell adhesion molecule 2 21 20998315-21543329 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA030900, HPA030901 Supported Supported Nuclear bodies
Plasma membrane Tissue enhanced Tissue enhanced cerebral cortex: 68.8 adrenal gland: 15.8 Cell line enhanced T-47d: 86.4;WM-115: 22.5 +L3MBTL4 FLJ35936, HsT1031 ENSG00000154655 L(3)mbt-like 4 (Drosophila) 18 5954706-6415237 Predicted intracellular proteins Evidence at protein level HPA064194, HPA069042 Approved Approved Nucleoplasm
Vesicles Mixed Mixed testis: 23.4 Cell line enhanced RPMI-8226: 8.0;SCLC-21H: 6.3;SH-SY5Y: 6.2 +PDE1C Hcam3 ENSG00000154678 Phosphodiesterase 1C 7 31751179-32299329 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021751, HPA052375 Uncertain Approved Nucleus Tissue enhanced Tissue enhanced heart muscle: 37.2 cerebral cortex: 20.8 Cell line enhanced fHDF/TERT166: 114.5;U-251 MG: 66.4;WM-115: 102.6 +RABGEF1 rabex-5, RABEX5 ENSG00000154710 RAB guanine nucleotide exchange factor 1 7 66682164-66811464 Predicted intracellular proteins Evidence at protein level HPA001407 Supported Nucleoli
Cytosol Glioma:2.90e-5 (unfavourable), Renal cancer:1.27e-4 (favourable) Expressed in all Expressed in all bone marrow: 49.5 Expressed in all +MRPL39 C21orf92, FLJ20451, L39mt, MGC104174, MGC3400, MRP-L5, MSTP003, PRED22, PRED66, RPML5 ENSG00000154719 Mitochondrial ribosomal protein L39 21 25585656-25607517 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA018331 Approved Pancreatic cancer:5.84e-4 (unfavourable) Expressed in all Expressed in all testis: 94.7 Expressed in all +JAM2 C21orf43, CD322, JAM-B, JAMB, VE-JAM ENSG00000154721 Junctional adhesion molecule 2 21 25639272-25717562 CD markers, Predicted membrane proteins Evidence at protein level HPA028789, HPA077346 Supported Nucleoplasm
Plasma membrane Tissue enriched Tissue enhanced placenta: 92.9 cerebral cortex: 34.2 Cell line enhanced AF22: 25.3;BJ hTERT+: 13.4;HDLM-2: 15.5;U-138 MG: 18.0;U-87 MG: 13.2 +ATP5J ATP5, ATP5A, ATPM, CF6 ENSG00000154723 ATP synthase, H+ transporting, mitochondrial Fo complex subunit F6 21 25716503-25735673 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031069 Supported Supported Mitochondria Renal cancer:2.37e-5 (favourable) Expressed in all Expressed in all heart muscle: 528.8 Expressed in all +GABPA E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A ENSG00000154727 GA binding protein transcription factor alpha subunit 21 25734570-25772460 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003258, CAB004411, HPA028791 Supported Enhanced Nucleoplasm Renal cancer:3.97e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 38.1 Expressed in all +ADAMTS1 C3-C5, KIAA1346, METH1 ENSG00000154734 ADAM metallopeptidase with thrombospondin type 1 motif 1 21 26835747-26845409 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB016394 Uncertain Head and neck cancer:5.13e-4 (unfavourable) Expressed in all Tissue enhanced ovary: 412.9 adipose tissue: 279.9 Cell line enhanced BJ: 346.6;hTEC/SVTERT24-B: 277.6 +ADAMTS5 ADAMTS11, ADMP-2 ENSG00000154736 ADAM metallopeptidase with thrombospondin type 1 motif 5 21 26917912-26966513 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA005661, CAB025996, HPA030906, HPA030908 Approved Supported Nucleoplasm Renal cancer:2.46e-4 (unfavourable), Thyroid cancer:8.54e-4 (unfavourable) Mixed Tissue enhanced placenta: 42.4 ovary: 24.3 Cell line enhanced ASC diff: 26.2;fHDF/TERT166: 12.4;RH-30: 40.0;U-87 MG: 14.5 +TSEN2 MGC2776, SEN2, SEN2L ENSG00000154743 TRNA splicing endonuclease subunit 2 3 12484432-12539623 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027120, HPA027125, HPA027268 Approved Enhanced Nucleoplasm
Cytosol Liver cancer:1.13e-5 (unfavourable), Urothelial cancer:3.49e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 14.7 Expressed in all +SLFN13 FLJ31952 ENSG00000154760 Schlafen family member 13 17 35435096-35448837 Predicted intracellular proteins Evidence at protein level HPA022532, HPA023064 Uncertain Approved Cytokinetic bridge Cervical cancer:3.82e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 41.2 fallopian tube: 26.9 Cell line enhanced HL-60: 104.7;REH: 68.4;U-266/70: 48.2 +WNT7A ENSG00000154764 Wnt family member 7A 3 13816258-13880121 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015719, CAB025894 Approved Pancreatic cancer:3.03e-6 (unfavourable), Endometrial cancer:2.96e-5 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 6.7;gallbladder: 3.6;placenta: 3.9 lung: 3.0 Group enriched 5 BEWO: 56.9;EFO-21: 52.0;PC-3: 18.2;RPTEC TERT1: 74.6 +XPC RAD4, XPCC ENSG00000154767 XPC complex subunit, DNA damage recognition and repair factor 3 14145147-14178783 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009932, HPA035707, HPA069673 Supported Enhanced Nucleus
Plasma membrane Renal cancer:4.14e-7 (favourable), Urothelial cancer:2.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 52.4 Expressed in all +CCDC174 C3orf19, FLJ33839 ENSG00000154781 Coiled-coil domain containing 174 3 14651746-14672659 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043468, HPA060129 Approved Enhanced Nucleoplasm Urothelial cancer:3.81e-5 (favourable), Prostate cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all ovary: 18.0 Expressed in all +FGD5 FLJ00274, FLJ39957, ZFYVE23 ENSG00000154783 FYVE, RhoGEF and PH domain containing 5 3 14810853-14934565 Predicted intracellular proteins Evidence at protein level HPA014536, HPA019191 Uncertain Urothelial cancer:7.50e-4 (favourable) Expressed in all Mixed spleen: 35.0 Group enriched 8 HUVEC TERT2: 80.3;TIME: 64.8;U-2197: 19.8 +FLCN BHD, MGC17998, MGC23445 ENSG00000154803 Folliculin 17 17212212-17237188 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015158, HPA028760 Supported Supported Plasma membrane
Cytosol Pancreatic cancer:4.49e-4 (favourable) Expressed in all Expressed in all endometrium: 30.8 Expressed in all +DPH3 DELGIP, DELGIP1, DESR1, DPH3A, KTI11, MGC20197, ZCSL2 ENSG00000154813 Diphthamide biosynthesis 3 3 16257978-16264972 Predicted intracellular proteins Evidence at protein level HPA035287 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:2.24e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 23.2 Expressed in all +OXNAD1 MGC15763 ENSG00000154814 Oxidoreductase NAD binding domain containing 1 3 16265160-16350299 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036830, HPA059160 Approved Approved Nucleus Renal cancer:1.00e-7 (favourable), Urothelial cancer:7.63e-4 (favourable) Expressed in all Mixed lymph node: 19.7 Expressed in all +PLCL2 KIAA1092, PLCE2 ENSG00000154822 Phospholipase C like 2 3 16802651-17090594 Predicted intracellular proteins Evidence at protein level HPA047616 Uncertain Renal cancer:2.98e-10 (favourable) Expressed in all Mixed ovary: 15.2 Cell line enhanced Daudi: 17.6;HAP1: 25.5 +CXXC1 CFP1, CGBP, hCGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1 ENSG00000154832 CXXC finger protein 1 18 50282343-50288304 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044511 Supported Enhanced Nucleus Liver cancer:4.18e-6 (unfavourable), Pancreatic cancer:2.60e-4 (favourable) Expressed in all Expressed in all fallopian tube: 28.8 Expressed in all +SKA1 C18orf24, MGC10200 ENSG00000154839 Spindle and kinetochore associated complex subunit 1 18 50374995-50394173 Predicted intracellular proteins Evidence at protein level HPA045495 Approved Supported Microtubules Liver cancer:9.60e-8 (unfavourable) Mixed Tissue enhanced bone marrow: 5.5;testis: 5.9 lymph node: 4.1 Mixed +PPP4R1 PP4R1 ENSG00000154845 Protein phosphatase 4 regulatory subunit 1 18 9546791-9615240 Predicted intracellular proteins Evidence at protein level HPA040905, HPA041089 Uncertain Approved Nucleoplasm Expressed in all Expressed in all esophagus: 78.2 Expressed in all +APCDD1 B7323 ENSG00000154856 APC down-regulated 1 18 10454628-10489948 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Endometrial cancer:6.39e-4 (favourable) Expressed in all Tissue enhanced skin: 153.1 cerebral cortex: 60.6 Cell line enhanced AF22: 31.6;BJ hTERT+: 56.8;HaCaT: 37.9;HSkMC: 28.6 +PIEZO2 C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771 ENSG00000154864 Piezo type mechanosensitive ion channel component 2 18 10666483-11148762 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA015986, HPA031974, HPA031975, HPA040616 Enhanced Approved Vesicles Renal cancer:9.57e-7 (unfavourable) Mixed Mixed lung: 12.8 Cell line enhanced AF22: 17.1;BJ hTERT+ SV40 Large T+ RasG12V: 24.8;HeLa: 26.7;U-266/70: 19.5 +MPPE1 ENSG00000154889 Metallophosphoesterase 1 18 11882622-11909223 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012639 Uncertain Approved Nucleoplasm
Golgi apparatus Renal cancer:6.45e-7 (favourable), Melanoma:1.35e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 78.0 Expressed in all +USP43 FLJ30626 ENSG00000154914 Ubiquitin specific peptidase 43 17 9644698-9729691 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023389, HPA027762 Uncertain Stomach cancer:5.39e-4 (favourable) Mixed Mixed placenta: 11.9 Cell line enhanced BEWO: 11.2;T-47d: 9.2 +RAB6B ENSG00000154917 RAB6B, member RAS oncogene family 3 133824239-133895836 Predicted intracellular proteins Evidence at protein level CAB017713, HPA059131 Uncertain Approved Golgi apparatus Pancreatic cancer:3.97e-6 (favourable), Endometrial cancer:9.01e-4 (unfavourable) Expressed in all Group enriched 5 cerebral cortex: 211.3;parathyroid gland: 77.1 fallopian tube: 26.2 Cell line enhanced HEL: 207.7;K-562: 49.3;SCLC-21H: 56.7 +EME1 FLJ31364, MMS4L, SLX2A ENSG00000154920 Essential meiotic structure-specific endonuclease 1 17 50373220-50381483 Predicted intracellular proteins Evidence at protein level CAB016127, HPA052188 Supported Approved Nuclear bodies
Cytosol Mixed Tissue enhanced epididymis: 7.7;testis: 9.8 bone marrow,lymph node: 2.8 Mixed +EPHB1 EPHT2, Hek6 ENSG00000154928 EPH receptor B1 3 134597801-135260467 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067740 Enhanced Approved Endoplasmic reticulum
Plasma membrane
Cytosol Tissue enriched Tissue enhanced cerebral cortex: 23.7;testis: 20.5 thyroid gland: 11.9 Cell line enhanced HDLM-2: 59.3;HMC-1: 31.7 +ACSS1 ACAS2L, AceCS2L, dJ568C11.3, MGC33843 ENSG00000154930 Acyl-CoA synthetase short-chain family member 1 20 25006230-25058980 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041014, HPA043228 Enhanced Lung cancer:8.33e-5 (favourable), Cervical cancer:9.37e-4 (favourable) Expressed in all Expressed in all placenta: 166.2 Cell line enhanced RPMI-8226: 51.0 +ANKRD40 MGC15396 ENSG00000154945 Ankyrin repeat domain 40 17 50693190-50707924 Predicted intracellular proteins Evidence at protein level HPA021668, HPA021759 Approved Approved Golgi apparatus
Cytosol Liver cancer:7.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 58.1 Expressed in all +ZNF18 HDSG1, KOX11, Zfp535, ZKSCAN6, ZNF535, ZSCAN38 ENSG00000154957 Zinc finger protein 18 17 11977439-11997510 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006144 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane
Cytosol Renal cancer:3.06e-6 (unfavourable), Pancreatic cancer:5.12e-6 (favourable), Cervical cancer:6.32e-4 (favourable) Expressed in all Expressed in all testis: 22.3 Expressed in all +CA10 CA-RPX, CARPX, HUCEP-15 ENSG00000154975 Carbonic anhydrase 10 17 51630313-52160017 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054825, HPA057837 Supported Approved Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 56.7;cervix, uterine: 32.1 testis: 10.7 Cell line enhanced RT4: 1.6;SCLC-21H: 7.3 +VOPP1 DKFZp564K0822, ECop, FLJ20532, GASP ENSG00000154978 Vesicular, overexpressed in cancer, prosurvival protein 1 7 55436056-55572988 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Renal cancer:6.99e-8 (unfavourable), Liver cancer:4.35e-5 (unfavourable) Expressed in all Expressed in all lymph node: 110.2 Mixed +SEPT14 FLJ44060 ENSG00000154997 Septin 14 7 55793544-55862789 Predicted intracellular proteins Evidence at protein level HPA073255 Enhanced Tissue enriched Tissue enriched 15 testis: 41.7 parathyroid gland: 2.7 Cell line enhanced BEWO: 6.0 +APOOL AAIR8193, CXorf33, FAM121A, Mic27, UNQ8193 ENSG00000155008 Apolipoprotein O like X 85003826-85093316 Predicted secreted proteins Evidence at protein level HPA000612 Enhanced Approved Mitochondria Renal cancer:1.35e-12 (favourable), Breast cancer:2.68e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.2 Expressed in all +DKK2 ENSG00000155011 Dickkopf WNT signaling pathway inhibitor 2 4 106921802-107283806 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB009727, HPA052611 Uncertain Supported Golgi apparatus Mixed Tissue enhanced cervix, uterine: 24.1 lung: 8.2 Cell line enriched 7 SH-SY5Y: 23.5 +CYP2U1 SPG49 ENSG00000155016 Cytochrome P450 family 2 subfamily U member 1 4 107931369-107953457 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA041622, HPA046754, HPA064827 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:2.75e-5 (favourable), Stomach cancer:6.97e-4 (unfavourable) Expressed in all Mixed prostate: 15.7 Mixed +RSPH10B ENSG00000155026 Radial spoke head 10 homolog B 7 5925550-5970683 Predicted intracellular proteins Evidence at protein level HPA049182 Supported Not detected Group enriched 8 fallopian tube: 13.4;testis: 35.8 parathyroid gland: 3.0 Not detected +FBXL18 Fbl18, FLJ11467 ENSG00000155034 F-box and leucine rich repeat protein 18 7 5431335-5513798 Predicted intracellular proteins Evidence at protein level HPA036049 Approved Nucleoplasm
Cytosol Cervical cancer:7.88e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 9.5 Expressed in all +CNTNAP5 caspr5, FLJ31966 ENSG00000155052 Contactin associated protein like 5 2 124025287-124915287 Predicted membrane proteins Evidence at protein level HPA069095, HPA069356 Supported Nucleus
Nucleoli fibrillar center
Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 5.8;gallbladder: 1.6 adrenal gland: 0.7 Cell line enhanced AF22: 1.1;SH-SY5Y: 2.8 +PROM2 ENSG00000155066 Prominin 2 2 95274453-95291308 Predicted membrane proteins Evidence at protein level CAB046005, HPA063728 Enhanced Approved Nucleoplasm
Plasma membrane
Cell Junctions Renal cancer:1.55e-6 (unfavourable), Breast cancer:2.16e-4 (unfavourable), Pancreatic cancer:2.90e-4 (unfavourable) Mixed Tissue enhanced skin: 71.1 esophagus: 44.6 Cell line enhanced A-431: 69.3;CAPAN-2: 119.5;HaCaT: 65.0;hTCEpi: 56.7;RT4: 66.9;SK-BR-3: 88.2 +AK9 AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1, FLJ25791, FLJ42177, MGC26954 ENSG00000155085 Adenylate kinase 9 6 109492856-109691217 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA030804, HPA030805, HPA031779, HPA031781, HPA036324, HPA036711 Enhanced Approved Nucleoplasm
Nuclear membrane Mixed Tissue enhanced testis: 31.2 parathyroid gland: 17.1 Expressed in all +ODF1 CT133, HSPB10, ODF27, ODFPG, RT7 ENSG00000155087 Outer dense fiber of sperm tails 1 8 102551572-102561017 Predicted intracellular proteins Evidence at protein level HPA064295 Approved Not detected Tissue enriched 1426 testis: 418.3 cerebral cortex: 0.2 Not detected +KLF10 EGRA, TIEG, TIEG1 ENSG00000155090 Kruppel like factor 10 8 102648779-102655902 Predicted intracellular proteins, Transcription factors Evidence at protein level Lung cancer:2.61e-5 (unfavourable) Expressed in all Expressed in all lung: 100.0 Expressed in all +PTPRN2 IA-2beta, ICAAR, KIAA0387, phogrin ENSG00000155093 Protein tyrosine phosphatase, receptor type N2 7 157539056-158587788 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006900, HPA026656 Approved Supported Vesicles Glioma:7.72e-5 (unfavourable), Renal cancer:8.68e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 82.3 stomach: 38.9 Cell line enhanced AF22: 28.0;HDLM-2: 38.8;NB-4: 27.1;SCLC-21H: 26.6;SH-SY5Y: 24.3;U-87 MG: 27.1 +AZIN1 OAZI, OAZIN, ODC1L ENSG00000155096 Antizyme inhibitor 1 8 102826357-102893864 Predicted intracellular proteins Evidence at protein level HPA027948 Approved Approved Vesicles Expressed in all Expressed in all cerebral cortex: 133.4 Expressed in all +ATP6V1C1 ATP6C, ATP6D, VATC, Vma5 ENSG00000155097 ATPase H+ transporting V1 subunit C1 8 103021063-103073051 Predicted intracellular proteins, Transporters Evidence at protein level HPA023943, HPA057297 Approved Supported Nucleoplasm
Cytosol Liver cancer:8.82e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 123.1 Expressed in all +TMEM55A DKFZp762O076 ENSG00000155099 Transmembrane protein 55A 8 90993796-91041064 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014591 Approved Liver cancer:3.76e-5 (unfavourable), Cervical cancer:1.01e-4 (unfavourable), Head and neck cancer:1.54e-4 (unfavourable), Stomach cancer:8.01e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 21.7 Mixed +OTUD6B CGI-77, DUBA5 ENSG00000155100 OTU domain containing 6B 8 91070196-91087095 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024046, HPA024503, HPA024772 Enhanced Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Breast cancer:7.50e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 17.2 Expressed in all +CDK19 bA346C16.3, CDC2L6, CDK11, KIAA1028 ENSG00000155111 Cyclin dependent kinase 19 6 110609978-110815958 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007053 Approved Approved Nucleoplasm
Vesicles Renal cancer:4.72e-5 (unfavourable), Liver cancer:3.56e-4 (unfavourable) Expressed in all Mixed prostate: 42.4 Expressed in all +GTF3C6 bA397G5.3, C6orf51, TFIIIC35 ENSG00000155115 General transcription factor IIIC subunit 6 6 110958560-110967890 Predicted intracellular proteins Evidence at protein level HPA056179, HPA061345 Approved Supported Nucleoplasm
Nuclear bodies Liver cancer:7.27e-6 (unfavourable) Expressed in all Expressed in all prostate: 101.0 Expressed in all +TTC39B C9orf52, FLJ33868 ENSG00000155158 Tetratricopeptide repeat domain 39B 9 15163622-15307360 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054804, HPA063162 Uncertain Approved Endoplasmic reticulum Renal cancer:4.08e-7 (favourable), Lung cancer:9.64e-6 (favourable) Expressed in all Mixed gallbladder: 11.0 Cell line enhanced HEL: 36.6 +AGPAT5 FLJ11210, LPAAT-e, LPAAT-epsilon ENSG00000155189 1-acylglycerol-3-phosphate O-acyltransferase 5 8 6708357-6759666 Enzymes, Predicted membrane proteins Evidence at protein level HPA010644, HPA010950 Approved Liver cancer:4.57e-4 (unfavourable), Colorectal cancer:8.82e-4 (favourable) Expressed in all Expressed in all testis: 46.9 Expressed in all +MMS19 hMMS19, MET18, MMS19L ENSG00000155229 MMS19 homolog, cytosolic iron-sulfur assembly component 10 97458324-97498794 Predicted intracellular proteins Evidence at protein level HPA051936, HPA056299 Approved Enhanced Nucleoplasm Urothelial cancer:3.39e-4 (unfavourable), Liver cancer:6.88e-4 (unfavourable) Expressed in all Expressed in all testis: 52.6 Expressed in all +OR4K1 ENSG00000155249 Olfactory receptor family 4 subfamily K member 1 14 19935608-19936683 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA028877 Uncertain Not detected Not detected testis: 0.3 Not detected +PI4K2A DKFZP761G1923, PI4KII, PIK42A ENSG00000155252 Phosphatidylinositol 4-kinase type 2 alpha 10 97640686-97676434 Enzymes, Predicted intracellular proteins Evidence at protein level CAB030649 Approved Colorectal cancer:4.21e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 31.3 Expressed in all +MARVELD1 bA548K23.8, FLJ22343, FLJ23440, GB14, MGC4415, MRVLDC1 ENSG00000155254 MARVEL domain containing 1 10 97713173-97718152 Predicted membrane proteins Evidence at protein level Renal cancer:8.89e-7 (unfavourable), Lung cancer:5.85e-5 (unfavourable) Expressed in all Mixed smooth muscle: 69.3 Mixed +ZFYVE27 FLJ32919, SPG33 ENSG00000155256 Zinc finger FYVE-type containing 27 10 97737121-97760907 Disease related genes, Predicted membrane proteins Evidence at protein level HPA037523, HPA069876 Approved Approved Nucleoplasm
Cytosol Colorectal cancer:6.91e-4 (unfavourable), Stomach cancer:7.54e-4 (favourable), Urothelial cancer:7.80e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 33.3 Expressed in all +GOLGA7B bA451M19.3, bA459F3.4, C10orf132, C10orf133 ENSG00000155265 Golgin A7 family member B 10 97850239-97871580 Predicted intracellular proteins Evidence at protein level HPA046878 Uncertain Mixed Group enriched 7 cerebral cortex: 18.3;epididymis: 28.5;skin: 17.4 adrenal gland: 3.1 Cell line enhanced A-431: 4.7;HDLM-2: 5.4;SK-MEL-30: 17.6 +GPR78 ENSG00000155269 G protein-coupled receptor 78 4 8558725-8619761 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013209 Uncertain Tissue enhanced Not detected all non-specific tissues: 0.0 Cell line enriched 194 BEWO: 19.5 +TRMT44 C4orf23, FLJ35725, METTL19, TRM44 ENSG00000155275 TRNA methyltransferase 44 homolog (S. cerevisiae) 4 8436140-8493531 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045461 Uncertain Approved Nucleoplasm Expressed in all Mixed endometrium: 10.0 Expressed in all +SLC25A28 MRS3/4, MRS4L ENSG00000155287 Solute carrier family 25 member 28 10 99610522-99620609 Predicted intracellular proteins, Transporters Evidence at protein level Cervical cancer:2.18e-6 (favourable), Renal cancer:7.28e-5 (unfavourable) Expressed in all Expressed in all testis: 93.6 Expressed in all +HSPA13 STCH ENSG00000155304 Heat shock protein family A (Hsp70) member 13 21 14371115-14383484 Predicted secreted proteins Evidence at protein level HPA014797 Approved Expressed in all Expressed in all cerebral cortex: 55.7 Expressed in all +SAMSN1 HACS1, NASH1, SASH2, SH3D6B, SLy2 ENSG00000155307 SAM domain, SH3 domain and nuclear localization signals 1 21 14485228-14583402 Predicted intracellular proteins Evidence at protein level HPA010645, HPA017055 Approved Enhanced Plasma membrane Renal cancer:4.52e-6 (unfavourable) Expressed in all Tissue enhanced appendix: 110.1;bone marrow: 123.6 spleen: 43.6 Cell line enhanced HEL: 244.0;K-562: 292.8;Karpas-707: 97.1 +USP25 USP21 ENSG00000155313 Ubiquitin specific peptidase 25 21 15730025-15880069 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018297, HPA024142 Approved Supported Cytosol Expressed in all Expressed in all testis: 97.6 Expressed in all +GRAMD3 FLJ21313, NS3TP2 ENSG00000155324 GRAM domain containing 3 5 126360132-126496494 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009678, HPA010095 Enhanced Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all Mixed thyroid gland: 69.1 Cell line enhanced BJ hTERT+: 93.5 +ZCCHC10 FLJ20094 ENSG00000155329 Zinc finger CCHC-type containing 10 5 132996985-133026604 Predicted intracellular proteins Evidence at protein level HPA038944 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all testis: 43.5 Expressed in all +C16orf87 ENSG00000155330 Chromosome 16 open reading frame 87 16 46796607-46831411 Predicted intracellular proteins Evidence at protein level HPA041179 Uncertain Approved Nucleoplasm Head and neck cancer:7.95e-5 (unfavourable), Pancreatic cancer:6.57e-4 (unfavourable) Expressed in all Tissue enhanced testis: 56.9 parathyroid gland: 34.3 Expressed in all +MOV10 fSAP113, gb110, MGC2948 ENSG00000155363 Mov10 RISC complex RNA helicase 1 112673141-112700746 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031627 Approved Cytosol Renal cancer:1.48e-11 (unfavourable), Liver cancer:3.44e-4 (unfavourable) Expressed in all Expressed in all placenta: 33.9 Mixed +RHOC ARH9, ARHC, RhoC ENSG00000155366 Ras homolog family member C 1 112701106-112707434 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA051461 Uncertain Renal cancer:3.65e-5 (unfavourable), Liver cancer:2.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 699.4 Expressed in all +PPM1J DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ ENSG00000155367 Protein phosphatase, Mg2+/Mn2+ dependent 1J 1 112709994-112715477 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046045 Uncertain Approved Vesicles Mixed Group enriched 6 epididymis: 22.8;skeletal muscle: 24.1;skin: 21.4;testis: 46.5 heart muscle: 4.7 Cell line enhanced T-47d: 18.2 +DBI ACBD1, ACBP ENSG00000155368 Diazepam binding inhibitor, acyl-CoA binding protein 2 119366921-119372560 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051428 Approved Renal cancer:3.73e-5 (unfavourable), Cervical cancer:5.77e-5 (favourable) Expressed in all Expressed in all breast: 907.6 Expressed in all +SLC16A1 MCT, MCT1 ENSG00000155380 Solute carrier family 16 member 1 1 112911847-112957013 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA003324, CAB017489, HPA071055, CAB079035 Enhanced Supported Enhanced Plasma membrane
Cell Junctions Renal cancer:6.78e-8 (unfavourable), Endometrial cancer:8.37e-6 (unfavourable), Pancreatic cancer:2.10e-4 (unfavourable), Lung cancer:4.05e-4 (unfavourable) Expressed in all Mixed testis: 31.4 Mixed +HEATR3 FLJ20718 ENSG00000155393 HEAT repeat containing 3 16 50065941-50106387 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041990, HPA058579 Uncertain Approved Nucleus
Cytosol Renal cancer:5.16e-6 (unfavourable), Liver cancer:4.11e-5 (unfavourable) Expressed in all Mixed appendix: 15.6 Expressed in all +TRIM74 MGC45440, TRIM50C ENSG00000155428 Tripartite motif containing 74 7 72959485-72969466 Predicted intracellular proteins Evidence at protein level HPA047843 Approved Cytosol Not detected Tissue enhanced stomach: 5.3 testis: 3.9 Cell line enhanced HEK 293: 3.5 +NIFK hNIFK, MKI67IP, Nopp34 ENSG00000155438 Nucleolar protein interacting with the FHA domain of MKI67 2 121726945-121736923 Predicted intracellular proteins Evidence at protein level CAB015382, HPA035735, HPA035736, CAB075728, CAB075729 Supported Enhanced Nucleoli Renal cancer:5.01e-11 (unfavourable), Liver cancer:2.92e-6 (unfavourable), Endometrial cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all lymph node: 49.6 Expressed in all +OXA1L MGC133129, OXA1 ENSG00000155463 OXA1L, mitochondrial inner membrane protein 14 22766522-22773041 Predicted membrane proteins, Transporters Evidence at protein level HPA003531 Approved Supported Mitochondria Renal cancer:4.82e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 142.6 Expressed in all +SLC7A7 LPI, y+LAT-1 ENSG00000155465 Solute carrier family 7 member 7 14 22773222-22829820 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA036227 Enhanced Renal cancer:6.28e-6 (unfavourable) Expressed in all Tissue enhanced kidney: 281.9 parathyroid gland: 162.5 Group enriched 5 BEWO: 191.5;CACO-2: 274.5;EFO-21: 65.6 +MAGEC1 CT7, CT7.1, MAGE-C1, MGC39366 ENSG00000155495 MAGE family member C1 X 141903894-141909388 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004622, CAB015452 Enhanced Approved Nucleoplasm
Cytosol Tissue enhanced Tissue enriched 134 testis: 13.3 all non-specific tissues: 0.0 Group enriched 8 K-562: 48.3;Karpas-707: 36.9;U-2 OS: 35.6;U-2197: 60.6;U-266/70: 35.4;U-266/84: 30.8 +LARP1 KIAA0731, LARP, MGC19556 ENSG00000155506 La ribonucleoprotein domain family member 1 5 154712902-154817607 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015222, HPA051397, HPA054819 Supported Supported Nucleus
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all parathyroid gland: 152.1 Expressed in all +CNOT8 CAF1, CALIF, hCAF1, POP2 ENSG00000155508 CCR4-NOT transcription complex subunit 8 5 154857553-154876793 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051398 Approved Liver cancer:5.33e-4 (unfavourable), Urothelial cancer:6.41e-4 (favourable) Expressed in all Expressed in all bone marrow: 74.6 Expressed in all +GRIA1 GluA1, GLUR1, GLURA ENSG00000155511 Glutamate ionotropic receptor AMPA type subunit 1 5 153489615-153813869 FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB001965, HPA035202 Supported Tissue enriched Tissue enriched 6 cerebral cortex: 67.1 lung: 10.6 Cell line enhanced AF22: 11.5;BJ: 4.7;LHCN-M2: 6.9;U-266/70: 4.4 +LRGUK CFAP246, FLJ32786 ENSG00000155530 Leucine rich repeats and guanylate kinase domain containing 7 134127299-134264591 Predicted intracellular proteins Evidence at protein level HPA029505, HPA029506 Uncertain Mixed Group enriched 8 epididymis: 1.7;fallopian tube: 5.4;testis: 8.4 lung,thyroid gland: 0.6 Cell line enhanced NTERA-2: 1.4;SH-SY5Y: 1.3;SK-MEL-30: 1.4 +SETD9 C5orf35, MGC33648 ENSG00000155542 SET domain containing 9 5 56909260-56925532 Predicted intracellular proteins Evidence at protein level HPA049936 Approved Nucleoplasm Expressed in all Tissue enriched 6 testis: 27.1 thyroid gland: 4.3 Mixed +MIER3 DKFZp686L09111, DKFZp781I1119, FLJ35954 ENSG00000155545 MIER family member 3 5 56919602-56971675 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058349, HPA065946 Uncertain Enhanced Nucleoplasm Expressed in all Expressed in all colon: 30.2 Expressed in all +NUP205 C7orf14, KIAA0225 ENSG00000155561 Nucleoporin 205 7 135557919-135648757 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Liver cancer:1.90e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.3 Expressed in all +ZKSCAN2 FLJ23199, ZNF694, ZSCAN34 ENSG00000155592 Zinc finger with KRAB and SCAN domains 2 16 25236001-25257931 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049141 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus Renal cancer:1.70e-6 (favourable) Expressed in all Mixed testis: 7.6 Mixed +C9orf85 MGC61599 ENSG00000155621 Chromosome 9 open reading frame 85 9 71911510-71986054 Predicted intracellular proteins Evidence at protein level HPA050767 Approved Nucleus
Nucleoli
Golgi apparatus Expressed in all Expressed in all thyroid gland: 13.9 Mixed +XAGE2 CT12.2, GAGED3, XAGE-2, XAGE2B ENSG00000155622 X antigen family member 2 X 52369030-52375680 Predicted intracellular proteins Evidence at protein level HPA052507, HPA060900 Supported Mixed Tissue enriched 35 placenta: 294.4 lung: 8.4 Cell line enhanced BEWO: 95.0;SK-BR-3: 17.4;T-47d: 19.2 +PIK3AP1 BCAP, FLJ35564 ENSG00000155629 Phosphoinositide-3-kinase adaptor protein 1 10 96593312-96720514 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026136, HPA038452 Enhanced Approved Nucleus
Plasma membrane
Cytosol Expressed in all Tissue enhanced spleen: 85.6 lymph node: 72.0 Cell line enhanced Daudi: 60.8;REH: 166.9;THP-1: 62.4;U-698: 79.5;U-937: 74.4 +RBM45 DRB1, FLJ44612 ENSG00000155636 RNA binding motif protein 45 2 178112424-178139011 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020448 Approved Supported Nucleus Renal cancer:5.34e-9 (unfavourable), Liver cancer:5.74e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 12.4 Expressed in all +TTN CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD ENSG00000155657 Titin 2 178525989-178830802 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007042, CAB022682, HPA030048 Enhanced Tissue enhanced Tissue enriched 7 skeletal muscle: 322.5 heart muscle: 46.7 Mixed +VSIG4 Z39IG ENSG00000155659 V-set and immunoglobulin domain containing 4 X 66021738-66040125 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA003903, CAB026000 Approved Uncertain Nucleoli
Plasma membrane
Cytosol Renal cancer:1.95e-6 (unfavourable), Colorectal cancer:1.34e-4 (unfavourable) Expressed in all Expressed in all lung: 243.4 Not detected +PDIA4 ERP70, ERP72 ENSG00000155660 Protein disulfide isomerase family A member 4 7 149003062-149028641 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA006139, HPA006140, CAB017368 Supported Supported Endoplasmic reticulum Renal cancer:5.20e-9 (unfavourable), Glioma:8.61e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 372.1 Expressed in all +KDM8 FLJ13798, JMJD5 ENSG00000155666 Lysine demethylase 8 16 27203495-27221768 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026545 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:1.75e-4 (favourable) Expressed in all Tissue enhanced liver: 24.2 small intestine: 13.8 Mixed +PDZD9 C16orf65, MGC50721 ENSG00000155714 PDZ domain containing 9 16 21983865-22001110 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 39 testis: 10.3 cerebral cortex: 0.2 Not detected +OTOA CT108, DFNB22 ENSG00000155719 Otoancorin 16 21678514-21760729 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041405 Uncertain Not detected Group enriched 13 spleen: 2.6;testis: 6.0 epididymis: 0.3 Not detected +KCTD18 6530404F10Rik, FLJ31322, FLJ37818 ENSG00000155729 Potassium channel tetramerization domain containing 18 2 200488952-200519784 Predicted intracellular proteins Evidence at protein level HPA045498, HPA058028 Approved Approved Mitochondria Expressed in all Expressed in all thyroid gland: 23.2 Expressed in all +FAM126B HYCC2, MGC39518 ENSG00000155744 Family with sequence similarity 126 member B 2 200973718-201071671 Predicted intracellular proteins Evidence at protein level HPA036166, HPA036167, HPA067307 Uncertain Supported Nucleus
Cell Junctions Expressed in all Mixed cerebral cortex: 14.7 Expressed in all +ALS2CR12 ENSG00000155749 Amyotrophic lateral sclerosis 2 chromosome region 12 2 201288271-201357398 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035793 Approved Plasma membrane
Cytosol Not detected Group enriched 5 fallopian tube: 15.0;testis: 31.8 lung: 4.2 Cell line enhanced U-2197: 4.3 +ALS2CR11 FLJ25351 ENSG00000155754 Amyotrophic lateral sclerosis 2 chromosome region candidate 11 2 201487425-201619178 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 78 testis: 74.2 ovary: 0.9 Cell line enhanced hTEC/SVTERT24-B: 2.0;SCLC-21H: 2.8;U-2197: 7.1 +TMEM237 ALS2CR4, JBTS14 ENSG00000155755 Transmembrane protein 237 2 201620184-201643570 Disease related genes, Predicted membrane proteins Evidence at protein level HPA052596, HPA054732 Enhanced Renal cancer:7.96e-6 (unfavourable), Melanoma:1.33e-4 (unfavourable), Endometrial cancer:2.51e-4 (unfavourable) Expressed in all Mixed skin: 21.9 Expressed in all +FZD7 FzE3 ENSG00000155760 Frizzled class receptor 7 2 202034587-202038445 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA069165 Approved Approved Nucleoplasm Liver cancer:7.71e-5 (unfavourable) Expressed in all Mixed seminal vesicle: 39.1 Cell line enhanced CAPAN-2: 63.3 +SPAG17 CT143, FLJ34497, PF6, RP4-776P7.2 ENSG00000155761 Sperm associated antigen 17 1 117953861-118185223 Predicted intracellular proteins Evidence at protein level HPA028597, HPA028666 Enhanced Mixed Tissue enhanced fallopian tube: 13.6;testis: 27.9 esophagus: 6.8 Not detected +DEPTOR DEP.6, DEPDC6, FLJ12428 ENSG00000155792 DEP domain containing MTOR interacting protein 8 119873717-120050913 Predicted intracellular proteins Evidence at protein level CAB020841, HPA023938, HPA023945, HPA024011 Enhanced Supported Nucleoplasm
Mitochondria Expressed in all Expressed in all thyroid gland: 163.8 Cell line enhanced Daudi: 74.2;RPMI-8226: 128.8;RPTEC TERT1: 111.5 +FMN2 ENSG00000155816 Formin 2 1 240014348-240475189 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050649 Approved Plasma membrane
Actin filaments Group enriched Group enriched 6 cerebral cortex: 53.8;parathyroid gland: 33.5 adrenal gland: 7.0 Cell line enhanced BJ: 60.2;fHDF/TERT166: 54.7;LHCN-M2: 63.8;U-138 MG: 48.9;WM-115: 77.8 +RNF20 BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779 ENSG00000155827 Ring finger protein 20 9 101533851-101563344 Enzymes, Predicted intracellular proteins Evidence at protein level CAB012478, HPA051773 Supported Enhanced Nucleoplasm Renal cancer:1.64e-6 (favourable) Expressed in all Expressed in all testis: 59.3 Expressed in all +CYLC2 ENSG00000155833 Cylicin 2 9 102995311-103018488 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 532 testis: 80.1 urinary bladder: 0.1 Not detected +PPARGC1B PERC, PGC1B ENSG00000155846 PPARG coactivator 1 beta 5 149730298-149855022 Predicted intracellular proteins Evidence at protein level HPA050543 Supported Nucleus Mixed Mixed parathyroid gland: 14.6 Mixed +ELMO1 CED-12, CED12, ELMO-1, KIAA0281 ENSG00000155849 Engulfment and cell motility 1 7 36854361-37449249 Predicted intracellular proteins Evidence at protein level Renal cancer:3.27e-5 (unfavourable), Pancreatic cancer:4.62e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 136.9 Cell line enhanced U-698: 82.2 +SLC26A2 DTD, DTDST ENSG00000155850 Solute carrier family 26 member 2 5 149960737-149993455 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041957, HPA058090 Enhanced Approved Vesicles Renal cancer:3.27e-4 (unfavourable), Liver cancer:4.66e-4 (unfavourable), Endometrial cancer:7.29e-4 (favourable) Expressed in all Tissue enhanced colon: 213.0;rectum: 207.1 parathyroid gland: 82.7 Expressed in all +LSM11 FLJ38273 ENSG00000155858 LSM11, U7 small nuclear RNA associated 5 157743695-157760709 Predicted intracellular proteins Evidence at protein level HPA039587 Uncertain Supported Nucleus
Nuclear bodies Expressed in all Mixed cerebral cortex: 8.5 Mixed +MED7 CRSP33, CRSP9 ENSG00000155868 Mediator complex subunit 7 5 157137412-157159019 Predicted intracellular proteins Evidence at protein level HPA067181 Supported Nuclear bodies Liver cancer:2.37e-5 (unfavourable), Renal cancer:8.69e-5 (favourable) Expressed in all Expressed in all testis: 46.7 Expressed in all +SAXO1 C9orf138, FAM154A, MGC35182 ENSG00000155875 Stabilizer of axonemal microtubules 1 9 18927658-19049354 Predicted intracellular proteins Evidence at protein level HPA023899 Enhanced Not detected Tissue enriched 112 testis: 58.4 epididymis: 0.5 Not detected +RRAGA FIP-1, RAGA ENSG00000155876 Ras related GTP binding A 9 19049395-19050983 Predicted intracellular proteins Evidence at protein level HPA003734 Supported Approved Golgi apparatus
Vesicles Head and neck cancer:7.43e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 128.1 Expressed in all +SLC24A2 NCKX2 ENSG00000155886 Solute carrier family 24 member 2 9 19507452-19786928 Predicted membrane proteins, Transporters Evidence at protein level Tissue enhanced Tissue enriched 7 cerebral cortex: 51.6 adrenal gland: 7.9 Cell line enhanced K-562: 2.3;SCLC-21H: 2.6;U-87 MG: 2.9 +TRIM42 FLJ40097, PPP1R40, T4A1 ENSG00000155890 Tripartite motif containing 42 3 140678039-140701150 Predicted intracellular proteins Evidence at protein level HPA003581, HPA022481 Uncertain Nucleoplasm
Mitochondria Not detected Tissue enriched 293 testis: 29.2 all non-specific tissues: 0.0 Not detected +PXYLP1 ACPL2, FLJ23751 ENSG00000155893 2-phosphoxylose phosphatase 1 3 141228726-141367753 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017243 Approved Expressed in all Expressed in all epididymis: 180.6 Mixed +ADCY8 AC8, ADCY3, HBAC1 ENSG00000155897 Adenylate cyclase 8 8 130780301-131042426 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB018652, HPA024291 Supported Group enriched Group enriched 8 cerebral cortex: 12.9;epididymis: 27.8;fallopian tube: 6.2 seminal vesicle: 2.0 Group enriched 7 U-138 MG: 17.5;U-87 MG: 33.7 +RASA2 GAP1M ENSG00000155903 RAS p21 protein activator 2 3 141487047-141615342 Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA035374, HPA035375 Approved Approved Vesicles Renal cancer:7.62e-7 (unfavourable), Urothelial cancer:4.34e-5 (favourable) Expressed in all Mixed lymph node: 25.0 Expressed in all +RMND1 bA351K16.3, C6orf96, FLJ20627, RMD1 ENSG00000155906 Required for meiotic nuclear division 1 homolog 6 151404763-151452181 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031397, HPA031398, HPA031399 Approved Supported Mitochondria Head and neck cancer:6.96e-4 (unfavourable) Expressed in all Expressed in all kidney: 44.1 Expressed in all +RAET1L ENSG00000155918 Retinoic acid early transcript 1L 6 150018334-150025532 Predicted membrane proteins Evidence at protein level Lung cancer:4.09e-4 (unfavourable) Tissue enhanced Tissue enriched 7 esophagus: 38.9 tonsil: 5.9 Cell line enriched 6 HaCaT: 15.6 +SLA hSLAP, SLA1, SLAP, SLAP-1 ENSG00000155926 Src like adaptor 8 133036724-133103054 Predicted intracellular proteins Evidence at protein level HPA012296, HPA074192 Approved Approved Nuclear membrane Expressed in all Tissue enhanced appendix: 104.2 lymph node: 79.7 Cell line enhanced HMC-1: 39.6;Karpas-707: 88.0;MOLT-4: 27.3;U-266/84: 51.3;U-937: 38.7 +TMBIM4 CGI-119, GAAP, LFG4, S1R, ZPRO ENSG00000155957 Transmembrane BAX inhibitor motif containing 4 12 66135846-66170072 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA077642 Supported Golgi apparatus Expressed in all Expressed in all thyroid gland: 164.3 Expressed in all +VBP1 PFD3, PFDN3 ENSG00000155959 VHL binding protein 1 X 155197007-155239817 Predicted intracellular proteins Evidence at protein level CAB006260, HPA023230 Approved Supported Vesicles
Cytosol Expressed in all Expressed in all cerebral cortex: 85.3 Expressed in all +RAB39B MRX72 ENSG00000155961 RAB39B, member RAS oncogene family X 155258241-155264589 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001114, HPA042505 Approved Breast cancer:8.95e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 19.4 epididymis: 7.5 Cell line enhanced Daudi: 19.2;Karpas-707: 24.8;SCLC-21H: 15.4;U-266/70: 26.3;U-266/84: 17.9 +CLIC2 XAP121 ENSG00000155962 Chloride intracellular channel 2 X 155276211-155334657 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA047381, HPA060101 Uncertain Approved Plasma membrane Renal cancer:1.74e-5 (unfavourable) Expressed in all Mixed spleen: 62.8 Cell line enhanced HDLM-2: 85.0;K-562: 44.8;Karpas-707: 31.6;RPMI-8226: 54.1 +AFF2 FMR2, FRAXE ENSG00000155966 AF4/FMR2 family member 2 X 148500619-149000663 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003139 Approved Mixed Tissue enhanced epididymis: 14.5;placenta: 21.1 bone marrow: 8.3 Cell line enhanced Daudi: 52.9;HL-60: 25.2;U-698: 74.2;U-937: 18.0 +MICU3 DKFZp313A0139, EFHA2 ENSG00000155970 Mitochondrial calcium uptake family member 3 8 17027238-17122644 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024048, HPA024771, HPA024779 Uncertain Mixed Tissue enhanced cerebral cortex: 34.8 parathyroid gland: 14.2 Cell line enhanced HBF TERT88: 12.3 +GRIP1 ENSG00000155974 Glutamate receptor interacting protein 1 12 66347431-66804186 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038856 Uncertain Mixed Mixed seminal vesicle: 11.6 Cell line enhanced BEWO: 22.7;HaCaT: 17.8;RT4: 17.2 +VPS37A FLJ32642, HCRP1, PQBP2, SPG53 ENSG00000155975 VPS37A, ESCRT-I subunit 8 17246571-17302427 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024705, HPA024781 Enhanced Approved Vesicles
Centrosome
Cytosol Expressed in all Expressed in all testis: 57.3 Expressed in all +KIF5A D12S1889, MY050, NKHC, SPG10 ENSG00000155980 Kinesin family member 5A 12 57549998-57586632 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA004469, HPA073448 Enhanced Approved Approved Nucleoplasm
Mitotic spindle
Cytosol Pancreatic cancer:5.23e-4 (favourable) Tissue enriched Tissue enriched 28 cerebral cortex: 325.7 adrenal gland: 11.4 Cell line enhanced HDLM-2: 28.1;NTERA-2: 15.0;SCLC-21H: 36.2 +NAT2 AAC2 ENSG00000156006 N-acetyltransferase 2 8 18391245-18401218 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA043704 Uncertain Colorectal cancer:4.61e-5 (favourable) Tissue enhanced Group enriched 13 colon: 14.4;duodenum: 32.7;liver: 62.4;rectum: 14.0;small intestine: 27.1 smooth muscle: 2.3 Cell line enhanced RT4: 1.2;SCLC-21H: 2.5;SK-BR-3: 1.0 +MAGEA8 CT1.8, MAGE8, MGC2182 ENSG00000156009 MAGE family member A8 X 149881141-149885835 Predicted intracellular proteins Evidence at protein level HPA003998 Enhanced Mixed Tissue enriched 9 placenta: 19.0 testis: 2.0 Group enriched 27 U-2 OS: 35.5;U-266/70: 48.5 +PSD3 DKFZp761K1423, EFA6D, EFA6R, HCA67, KIAA0942 ENSG00000156011 Pleckstrin and Sec7 domain containing 3 8 18527301-19084730 Predicted intracellular proteins Evidence at protein level HPA002455 Enhanced Approved Nucleus
Vesicles Endometrial cancer:5.76e-5 (unfavourable), Colorectal cancer:7.55e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 83.3 testis: 29.6 Cell line enhanced U-87 MG: 48.5 +CARNMT1 C9orf41, FLJ25795 ENSG00000156017 Carnosine N-methyltransferase 1 9 74981020-75028423 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026756 Uncertain Expressed in all Expressed in all testis: 30.0 Expressed in all +MCU C10orf42, CCDC109A, FLJ46135 ENSG00000156026 Mitochondrial calcium uniporter 10 72692131-72887694 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016480 Approved Supported Mitochondria Liver cancer:6.06e-5 (unfavourable), Renal cancer:5.07e-4 (favourable) Expressed in all Expressed in all stomach: 40.7 Expressed in all +ELMSAN1 C14orf117, C14orf43, LSR68 ENSG00000156030 ELM2 and Myb/SANT domain containing 1 14 73715122-73790285 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003111 Approved Enhanced Nucleoplasm Ovarian cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.2 Expressed in all +CFAP70 FLJ25765, TTC18 ENSG00000156042 Cilia and flagella associated protein 70 10 73253759-73358859 Predicted intracellular proteins Evidence at protein level HPA037582, HPA070304 Enhanced Mixed Tissue enhanced fallopian tube: 23.4;testis: 37.6 epididymis: 13.8 Mixed +GNA14 ENSG00000156049 G protein subunit alpha 14 9 77423079-77648307 Predicted intracellular proteins Evidence at protein level HPA048886 Approved Mixed Mixed thyroid gland: 29.8 Cell line enhanced BJ hTERT+: 1.9;PC-3: 3.0;U-2197: 2.0 +FAM161B C14orf44, FLJ31697 ENSG00000156050 Family with sequence similarity 161 member B 14 73931501-73950414 Predicted intracellular proteins Evidence at protein level HPA019125 Approved Renal cancer:6.78e-4 (favourable) Expressed in all Mixed testis: 18.8 Mixed +GNAQ G-ALPHA-q, GAQ ENSG00000156052 G protein subunit alpha q 9 77716087-78031458 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB010036, HPA048886 Uncertain Approved Nuclear speckles
Plasma membrane
Cytosol Renal cancer:1.11e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 84.9 Mixed +WIF1 ENSG00000156076 WNT inhibitory factor 1 12 65050626-65121566 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039104 Approved Tissue enhanced Tissue enriched 6 lung: 159.4 cerebral cortex: 26.4 Cell line enhanced HEK 293: 1.9;NTERA-2: 2.7 +UGT2B4 UGT2B11 ENSG00000156096 UDP glucuronosyltransferase family 2 member B4 4 69480165-69526014 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB033260, HPA045108 Enhanced Tissue enriched Tissue enriched 78 liver: 655.5 heart muscle: 8.3 Cell line enriched 11 RH-30: 4.5 +GPR61 BALGR ENSG00000156097 G protein-coupled receptor 61 1 109539872-109548406 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA007326, HPA026088 Approved Not detected Tissue enhanced adrenal gland: 1.0;cerebral cortex: 3.4;thyroid gland: 1.2 testis: 0.5 Not detected +MMP16 C8orf57, DKFZp761D112, MT3-MMP ENSG00000156103 Matrix metallopeptidase 16 8 88032009-88328025 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023693 Uncertain Approved Vesicles
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 9.6 gallbladder: 4.2 Cell line enhanced AN3-CA: 27.2;SH-SY5Y: 17.2;WM-115: 28.4 +ADK AK ENSG00000156110 Adenosine kinase 10 74151185-74709303 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB032876, HPA038391, HPA038409 Approved Supported Nucleoplasm
Cytosol Head and neck cancer:1.93e-4 (unfavourable), Liver cancer:9.91e-4 (favourable) Expressed in all Expressed in all liver: 77.6 Expressed in all +KCNMA1 KCa1.1, mSLO1, SLO ENSG00000156113 Potassium calcium-activated channel subfamily M alpha 1 10 76869601-77638369 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA054648 Approved Mixed Tissue enhanced smooth muscle: 137.0 endometrium: 109.5 Cell line enhanced PC-3: 148.0;U-138 MG: 111.0;U-87 MG: 107.5 +BATF B-ATF, BATF1, SFA-2 ENSG00000156127 Basic leucine zipper ATF-like transcription factor 14 75522425-75547015 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059588, HPA064962 Approved Enhanced Nucleoplasm Renal cancer:3.74e-9 (unfavourable), Endometrial cancer:5.35e-6 (favourable), Head and neck cancer:7.91e-5 (favourable), Urothelial cancer:4.30e-4 (favourable), Colorectal cancer:8.30e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 31.4 appendix: 26.5 Cell line enhanced HDLM-2: 321.9;MCF7: 99.6;RT4: 64.2;U-937: 74.7 +DCK ENSG00000156136 Deoxycytidine kinase 4 70992538-71030914 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA059609, HPA062773 Approved Supported Nucleus Liver cancer:6.90e-7 (unfavourable) Expressed in all Expressed in all lymph node: 93.9 Expressed in all +ADAMTS3 ADAMTS-4, KIAA0366 ENSG00000156140 ADAM metallopeptidase with thrombospondin type 1 motif 3 4 72280969-72569386 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA021368, HPA021369 Uncertain Approved Intermediate filaments Mixed Tissue enhanced parathyroid gland: 7.3 testis: 3.5 Cell line enhanced AF22: 13.0;HEL: 12.6;K-562: 10.9;U-2 OS: 8.7 +ALX3 FND ENSG00000156150 ALX homeobox 3 1 110059994-110070700 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Mixed skin: 7.7 Mixed +DPY19L4 ENSG00000156162 Dpy-19 like 4 (C. elegans) 8 94719703-94793836 Predicted membrane proteins Evidence at protein level HPA024780 Approved Approved Vesicles Endometrial cancer:3.73e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.9 Expressed in all +NDUFAF6 C8orf38, MGC40214 ENSG00000156170 NADH:ubiquinone oxidoreductase complex assembly factor 6 8 94895767-95116455 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047148, HPA050545 Approved Expressed in all Mixed thyroid gland: 10.5 Expressed in all +DRAM2 MGC54289, PRO180, RP5-1180E21.1, TMEM77, WWFQ154 ENSG00000156171 DNA damage regulated autophagy modulator 2 1 111117333-111140216 Predicted membrane proteins Evidence at protein level HPA018036, HPA061701 Enhanced Enhanced Golgi apparatus
Vesicles Liver cancer:3.45e-5 (unfavourable), Melanoma:6.43e-4 (unfavourable), Renal cancer:7.45e-4 (unfavourable) Expressed in all Mixed spleen: 19.3 Mixed +C8orf37 BBS21, CORD16, FLJ30600, RP64 ENSG00000156172 Chromosome 8 open reading frame 37 8 95244919-95269201 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024198 Approved Approved Plasma membrane
Cell Junctions
Cytosol Endometrial cancer:4.63e-4 (unfavourable) Expressed in all Mixed fallopian tube: 6.3 Mixed +PPEF2 PPP7CB ENSG00000156194 Protein phosphatase with EF-hand domain 2 4 75859864-75902571 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Not detected testis: 0.4 Not detected +CFAP161 C15orf26, FLJ38615 ENSG00000156206 Cilia and flagella associated protein 161 15 81007033-81149175 Predicted intracellular proteins Evidence at protein level HPA041807 Uncertain Endometrial cancer:3.05e-4 (favourable) Tissue enhanced Tissue enhanced fallopian tube: 24.8;testis: 11.5 lung: 4.1 Group enriched 5 HEL: 75.9;K-562: 25.9 +ADAMTSL3 KIAA1233, punctin-2 ENSG00000156218 ADAMTS like 3 15 83654086-84039842 Predicted secreted proteins Evidence at protein level HPA034773, HPA034774 Approved Approved Vesicles Mixed Mixed placenta: 14.9 Group enriched 6 EFO-21: 11.2;RPTEC TERT1: 10.6;TIME: 10.7;U-2 OS: 2.4 +ART3 ENSG00000156219 ADP-ribosyltransferase 3 4 76011184-76112802 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011268 Enhanced Tissue enhanced Tissue enhanced skeletal muscle: 77.0;testis: 174.4 heart muscle: 29.1 Group enriched 7 NB-4: 3.4;NTERA-2: 14.0;SK-MEL-30: 4.9 +SLC28A1 CNT1 ENSG00000156222 Solute carrier family 28 member 1 15 84884654-84945796 Predicted membrane proteins, Transporters Evidence at protein level HPA019551 Enhanced Group enriched Group enriched 26 duodenum: 37.9;kidney: 49.4;liver: 35.4;small intestine: 53.6 placenta: 1.7 Not detected +WHAMM KIAA1971, WHAMM1, WHDC1 ENSG00000156232 WAS protein homolog associated with actin, golgi membranes and microtubules 15 82809628-82836108 Predicted intracellular proteins Evidence at protein level HPA039690, HPA040231 Supported Supported Cytosol Prostate cancer:2.31e-4 (unfavourable), Cervical cancer:7.09e-4 (favourable) Expressed in all Expressed in all bone marrow: 18.8 Expressed in all +CXCL13 ANGIE, ANGIE2, BCA-1, BLC, BLR1L, SCYB13 ENSG00000156234 C-X-C motif chemokine ligand 13 4 77511753-77611834 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA052613 Uncertain Renal cancer:1.16e-10 (unfavourable), Ovarian cancer:5.41e-4 (favourable), Endometrial cancer:5.52e-4 (favourable), Colorectal cancer:9.12e-4 (favourable) Expressed in all Group enriched 7 appendix: 163.3;lymph node: 599.9;spleen: 423.8;tonsil: 395.7 urinary bladder: 57.9 Cell line enhanced U-266/70: 1.0 +N6AMT1 C21orf127, HEMK2, MTQ2, N6AMT, PRED28 ENSG00000156239 N-6 adenine-specific DNA methyltransferase 1 (putative) 21 28872191-28885371 Predicted intracellular proteins Evidence at protein level CAB034133, CAB034135, HPA059242 Approved Approved Nucleoplasm
Centrosome Expressed in all Mixed parathyroid gland: 10.8 Expressed in all +RWDD2B C21orf6, GL011 ENSG00000156253 RWD domain containing 2B 21 29004384-29019378 Predicted intracellular proteins Evidence at protein level HPA018316 Uncertain Expressed in all Mixed testis,thyroid gland: 1.8 Mixed +USP16 Ubp-M ENSG00000156256 Ubiquitin specific peptidase 16 21 29024629-29054488 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021140 Supported Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 57.2 Expressed in all +CCT8 C21orf112, Cctq, PRED71 ENSG00000156261 Chaperonin containing TCP1 subunit 8 21 29055805-29073797 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018520, HPA021051, HPA029426 Enhanced Approved Nucleus
Intermediate filaments
Cytosol Liver cancer:1.56e-5 (unfavourable) Expressed in all Expressed in all lymph node: 135.9 Expressed in all +MAP3K7CL C21orf7, TAK1L, TAKL, TAKL-1, TAKL-2, TAKL-4 ENSG00000156265 MAP3K7 C-terminal like 21 29077471-29175889 Predicted intracellular proteins Evidence at protein level HPA030079, HPA042439 Uncertain Approved Nucleoplasm Renal cancer:8.31e-6 (unfavourable) Expressed in all Mixed heart muscle: 17.9 Cell line enhanced HBF TERT88: 56.2;RH-30: 242.2 +NAA11 ARD1B, ARD2, hARD2 ENSG00000156269 N(alpha)-acetyltransferase 11, NatA catalytic subunit 4 79225694-79326050 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035922 Approved Tissue enhanced Group enriched 37 placenta: 6.1;testis: 11.4 cerebral cortex,endometrium,parathyroid gland,smooth muscle,thyroid gland: 0.2 Cell line enhanced K-562: 11.1;U-266/70: 25.3;U-266/84: 8.0 +BACH1 BACH-1, BTBD24 ENSG00000156273 BTB domain and CNC homolog 1 21 29194071-29630751 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034949 Approved Approved Nucleus
Cytosol Pancreatic cancer:3.11e-5 (unfavourable), Renal cancer:7.14e-4 (unfavourable) Expressed in all Expressed in all placenta: 71.9 Expressed in all +CLDN17 MGC126552, MGC126554 ENSG00000156282 Claudin 17 21 30165564-30166756 Predicted membrane proteins, Transporters Evidence at protein level HPA045903 Enhanced Tissue enhanced Tissue enriched 5 esophagus: 6.6 tonsil: 1.2 Not detected +CLDN8 ENSG00000156284 Claudin 8 21 30214006-30216073 Predicted membrane proteins, Transporters Evidence at protein level HPA060605 Supported Renal cancer:3.32e-4 (favourable) Tissue enhanced Tissue enhanced breast: 84.9;kidney: 76.1;rectum: 56.0 thyroid gland: 37.3 Cell line enriched 17 HaCaT: 30.1 +TSPAN7 A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2 ENSG00000156298 Tetraspanin 7 X 38561370-38688920 CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA003140, CAB062566, CAB068245 Enhanced Renal cancer:5.48e-7 (favourable), Pancreatic cancer:1.70e-4 (favourable), Endometrial cancer:3.40e-4 (unfavourable) Expressed in all Tissue enriched 6 cerebral cortex: 574.4 adrenal gland: 99.2 Cell line enhanced HDLM-2: 39.2;MOLT-4: 141.6;SCLC-21H: 109.6;U-266/70: 47.0 +TIAM1 ENSG00000156299 T-cell lymphoma invasion and metastasis 1 21 31118416-31559977 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010416, HPA034853 Uncertain Supported Nucleus
Nuclear membrane
Nucleoli
Cell Junctions
Cytokinetic bridge
Cytosol Mixed Mixed skin: 28.0 Cell line enhanced BEWO: 33.2;SCLC-21H: 38.3 +SCAF4 DKFZp434E098, KIAA1172, SFRS15, SRA4 ENSG00000156304 SR-related CTD associated factor 4 21 31671033-31732075 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018319, HPA018668, HPA021504, HPA028807 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all testis: 28.4 Expressed in all +RPGR COD1, CORDX1, CRD, RP15, RP3 ENSG00000156313 Retinitis pigmentosa GTPase regulator X 38269163-38327564 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001593, HPA073455 Approved Supported Golgi apparatus Expressed in all Expressed in all fallopian tube: 22.9 Mixed +CDK20 CCRK, p42 ENSG00000156345 Cyclin dependent kinase 20 9 87966441-87974753 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007666, HPA027379, HPA027401 Enhanced Supported Nucleoplasm Renal cancer:2.12e-5 (favourable), Endometrial cancer:2.59e-4 (favourable) Expressed in all Mixed fallopian tube: 20.7 Cell line enhanced SCLC-21H: 21.7;THP-1: 19.4 +PCGF6 MBLR, RNF134 ENSG00000156374 Polycomb group ring finger 6 10 103302796-103351134 Predicted intracellular proteins Evidence at protein level Renal cancer:4.54e-9 (unfavourable) Expressed in all Expressed in all testis: 16.2 Expressed in all +ANKRD9 ENSG00000156381 Ankyrin repeat domain 9 14 102501760-102509799 Predicted intracellular proteins Evidence at protein level HPA055985 Uncertain Renal cancer:1.17e-7 (favourable) Expressed in all Expressed in all duodenum: 50.3 Mixed +SFR1 bA373N18.1, C10orf78, FLJ41960, MEI5, MEIR5 ENSG00000156384 SWI5 dependent homologous recombination repair protein 1 10 104122058-104126385 Predicted intracellular proteins Evidence at protein level HPA039617 Uncertain Liver cancer:2.59e-5 (unfavourable), Renal cancer:2.23e-4 (unfavourable) Expressed in all Expressed in all testis: 33.1 Expressed in all +SORCS3 KIAA1059, SORCS ENSG00000156395 Sortilin related VPS10 domain containing receptor 3 10 104641101-105265235 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Renal cancer:5.72e-4 (unfavourable) Group enriched Tissue enhanced cerebral cortex: 11.9 adrenal gland: 2.6 Not detected +SFXN2 ENSG00000156398 Sideroflexin 2 10 102714538-102743492 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018150, HPA026834 Enhanced Approved Mitochondria Renal cancer:2.28e-5 (favourable), Cervical cancer:2.28e-4 (favourable), Urothelial cancer:6.52e-4 (favourable), Liver cancer:9.95e-4 (favourable) Expressed in all Tissue enhanced kidney: 18.7 parathyroid gland: 12.4 Cell line enhanced T-47d: 35.9 +C14orf2 MP68 ENSG00000156411 Chromosome 14 open reading frame 2 14 103912288-103928269 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058978, HPA060520 Enhanced Supported Nucleoli fibrillar center
Mitochondria Ovarian cancer:6.80e-4 (favourable) Expressed in all Expressed in all heart muscle: 209.1 Expressed in all +FUT6 FCT3A, FLJ40754, FT1A, FucT-VI ENSG00000156413 Fucosyltransferase 6 19 5830610-5839731 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043707, HPA046966 Approved Supported Golgi apparatus Renal cancer:3.17e-8 (favourable), Head and neck cancer:2.12e-4 (favourable) Mixed Tissue enhanced esophagus: 49.8;kidney: 34.5 small intestine: 30.6 Group enriched 5 Hep G2: 7.2;RPMI-8226: 2.7 +TDRD9 C14orf75, DKFZp434N0820, FLJ36164, NET54 ENSG00000156414 Tudor domain containing 9 14 103928462-104052667 Enzymes, Predicted intracellular proteins Evidence at protein level Thyroid cancer:5.52e-4 (unfavourable) Mixed Group enriched 6 parathyroid gland: 39.7;testis: 75.0 thyroid gland: 9.1 Cell line enhanced HDLM-2: 22.6;HeLa: 13.9;HMC-1: 82.8;RPTEC TERT1: 19.5 +FGF18 FGF-18, ZFGF5 ENSG00000156427 Fibroblast growth factor 18 5 171419656-171457623 Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA018795 Uncertain Group enriched Tissue enhanced heart muscle: 6.6 adipose tissue: 1.9 Cell line enriched 61 EFO-21: 178.4 +PCDH1 pc42 ENSG00000156453 Protocadherin 1 5 141853111-141879246 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA047720, HPA050538 Enhanced Approved Nucleus
Nucleoli
Cell Junctions Liver cancer:4.96e-5 (unfavourable), Renal cancer:7.55e-5 (favourable), Pancreatic cancer:3.61e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 40.3 Cell line enhanced CAPAN-2: 75.4;HaCaT: 95.1;RT4: 59.1;TIME: 60.2;WM-115: 51.1 +SH3RF2 FLJ23654, Hepp1, POSHER, PPP1R39, RNF158 ENSG00000156463 SH3 domain containing ring finger 2 5 145936579-146081791 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035903, HPA058119 Uncertain Approved Nucleoplasm Mixed Tissue enhanced skin: 67.3 heart muscle: 26.1 Cell line enhanced CACO-2: 57.4 +GDF6 BMP13, KFS, KFS1, SGM1 ENSG00000156466 Growth differentiation factor 6 8 96142330-96160792 Disease related genes, Predicted secreted proteins Evidence at protein level HPA045206 Uncertain Supported Nucleoplasm
Nuclear membrane
Vesicles Renal cancer:2.17e-4 (unfavourable) Tissue enhanced Tissue enhanced placenta: 15.1 gallbladder: 3.8 Cell line enriched 7 LHCN-M2: 27.7 +UQCRB QCR7, QP-C, UQBP, UQCR6 ENSG00000156467 Ubiquinol-cytochrome c reductase binding protein 8 96225920-96235634 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043060 Approved Renal cancer:2.90e-4 (favourable) Expressed in all Expressed in all heart muscle: 520.9 Expressed in all +MTERF3 CGI-12, FLJ10939, MTERFD1 ENSG00000156469 Mitochondrial transcription termination factor 3 8 96239398-96261610 Predicted intracellular proteins Evidence at protein level HPA002966 Supported Nucleoplasm
Mitochondria Renal cancer:5.88e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.4 Expressed in all +PTDSS1 KIAA0024, PSS1, PSSA ENSG00000156471 Phosphatidylserine synthase 1 8 96261715-96336995 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA016852 Uncertain Approved Nucleoplasm
Endoplasmic reticulum Liver cancer:1.08e-5 (unfavourable), Lung cancer:9.83e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 14.1 Expressed in all +PPP2R2B PR52B, PR55-BETA, SCA12 ENSG00000156475 Protein phosphatase 2 regulatory subunit Bbeta 5 146581146-147084784 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038118, HPA042122, HPA042770 Approved Approved Cytosol Tissue enriched Tissue enhanced cerebral cortex: 135.2 testis: 33.9 Cell line enhanced HaCaT: 19.5;HDLM-2: 97.5;RT4: 19.0 +RPL30 L30 ENSG00000156482 Ribosomal protein L30 8 98024851-98046469 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA002651 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:1.41e-9 (unfavourable) Expressed in all Expressed in all ovary: 5911.7 Expressed in all +KCNS2 Kv9.2 ENSG00000156486 Potassium voltage-gated channel modifier subfamily S member 2 8 98427022-98432848 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA051417 Uncertain Not detected Tissue enhanced cerebral cortex: 7.2 placenta: 2.2 Group enriched 9 HSkMC: 1.5;SCLC-21H: 7.5 +FAM122C RP3-473B4.1 ENSG00000156500 Family with sequence similarity 122C X 134796789-134854610 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA059961 Approved Uncertain Nucleoplasm Mixed Mixed testis: 7.9 Mixed +SUPV3L1 SUV3 ENSG00000156502 Suv3 like RNA helicase 10 69180232-69209099 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038380, HPA038405 Enhanced Supported Mitochondria Expressed in all Expressed in all testis: 29.0 Expressed in all +FAM122B DKFZp686L20116, RP11-308B5.5 ENSG00000156504 Family with sequence similarity 122B X 134769566-134797232 Predicted intracellular proteins Evidence at protein level HPA000266 Enhanced Approved Nucleoplasm Endometrial cancer:7.19e-5 (unfavourable) Expressed in all Expressed in all testis: 66.6 Expressed in all +EEF1A1 EE1A1, EEF1A, EF1A, LENG7 ENSG00000156508 Eukaryotic translation elongation factor 1 alpha 1 6 73515750-73523797 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051759, HPA053862, HPA056990 Supported Supported Cytosol Liver cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all ovary: 14741.4 Expressed in all +FBXO43 Fbx43 ENSG00000156509 F-box protein 43 8 100133360-100145800 Predicted intracellular proteins Evidence at protein level HPA024292, HPA024295, HPA024824 Uncertain Mixed Tissue enriched 18 testis: 9.8 tonsil: 0.5 Mixed +HKDC1 FLJ22761, FLJ37767 ENSG00000156510 Hexokinase domain containing 1 10 69220303-69267559 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011956, HPA064198, HPA064230 Approved Enhanced Mitochondria Mixed Tissue enhanced duodenum: 53.1;small intestine: 52.3 thyroid gland: 15.2 Group enriched 6 A549: 35.7;CACO-2: 46.7;CAPAN-2: 96.8;EFO-21: 31.5;Hep G2: 22.5;RPTEC TERT1: 61.4 +HK1 ENSG00000156515 Hexokinase 1 10 69269984-69401882 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007043, HPA007044, CAB010052, HPA011956 Supported Enhanced Mitochondria Head and neck cancer:3.39e-6 (unfavourable) Expressed in all Expressed in all testis: 153.6 Cell line enhanced K-562: 491.8 +TYSND1 MGC34695, NET41 ENSG00000156521 Trypsin domain containing 1 10 70137981-70146676 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030304 Uncertain Uncertain Nucleoplasm
Centrosome
Cytosol Expressed in all Mixed adipose tissue: 5.8 Cell line enhanced HaCaT: 24.4;PC-3: 39.1 +PHF6 BFLS, BORJ, CENP-31, KIAA1823, MGC14797 ENSG00000156531 PHD finger protein 6 X 134373253-134428791 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001023 Enhanced Enhanced Nucleus
Nucleoli Liver cancer:3.38e-4 (unfavourable), Pancreatic cancer:9.96e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 41.7 Expressed in all +CD109 CPAMD7, DKFZp762L1111, FLJ38569 ENSG00000156535 CD109 molecule 6 73695785-73828316 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA015723 Enhanced Stomach cancer:7.96e-5 (unfavourable), Renal cancer:2.65e-4 (unfavourable), Urothelial cancer:4.68e-4 (unfavourable) Expressed in all Tissue enriched 43 parathyroid gland: 967.3 skin: 22.4 Cell line enhanced ASC TERT1: 162.5 +LRFN2 FIGLER2, KIAA1246, SALM1 ENSG00000156564 Leucine rich repeat and fibronectin type III domain containing 2 6 40391586-40587465 Predicted membrane proteins Evidence at protein level HPA076660 Enhanced Supported Vesicles Not detected Tissue enriched 5 cerebral cortex: 6.8 testis: 1.3 Cell line enhanced REH: 1.5;SH-SY5Y: 5.0 +NODAL ENSG00000156574 Nodal growth differentiation factor 10 70432315-70447951 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045201 Uncertain Tissue enriched Tissue enhanced testis: 2.9 skin: 1.2 Cell line enhanced CACO-2: 1.6;SH-SY5Y: 1.5 +PRG3 MBP2, MBPH ENSG00000156575 Proteoglycan 3, pro eosinophil major basic protein 2 11 57376769-57381150 Predicted secreted proteins Evidence at protein level HPA064183 Enhanced Not detected Tissue enriched 45 bone marrow: 29.3 liver,spleen: 0.6 Cell line enriched 64 HMC-1: 174.6 +UBE2L6 UBCH8 ENSG00000156587 Ubiquitin conjugating enzyme E2 L6 11 57551656-57568284 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003328, CAB073407 Enhanced Approved Cytosol Pancreatic cancer:4.88e-4 (unfavourable), Breast cancer:6.75e-4 (favourable) Expressed in all Expressed in all spleen: 148.0 Mixed +ZDHHC5 KIAA1748, ZNF375 ENSG00000156599 Zinc finger DHHC-type containing 5 11 57667747-57701187 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014670 Approved Approved Nucleoplasm
Plasma membrane
Cell Junctions
Cytosol Pancreatic cancer:6.74e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 87.5 Expressed in all +MED19 LCMR1 ENSG00000156603 Mediator complex subunit 19 11 57703714-57712323 Predicted intracellular proteins Evidence at protein level HPA039912, HPA040860 Uncertain Supported Nucleus
Nuclear bodies Liver cancer:1.34e-6 (unfavourable), Ovarian cancer:1.76e-6 (favourable) Expressed in all Expressed in all testis: 28.6 Expressed in all +ZFAND3 FLJ13222, TEX27 ENSG00000156639 Zinc finger AN1-type containing 3 6 37819499-38154624 Predicted intracellular proteins Evidence at protein level HPA016755 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 185.0 Expressed in all +NPTN GP55, GP65, np55, np65, SDFR1, SDR1 ENSG00000156642 Neuroplastin 15 73560014-73634134 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051497, HPA072453 Approved Approved Cytokinetic bridge
Mitochondria Expressed in all Expressed in all smooth muscle: 433.8 Expressed in all +KAT6B Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B ENSG00000156650 Lysine acetyltransferase 6B 10 74825582-75032622 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006104 Supported Approved Nucleus
Nuclear bodies Renal cancer:4.82e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.3 Expressed in all +SAMD8 FLJ25082, SMSr ENSG00000156671 Sterile alpha motif domain containing 8 10 75099586-75182123 Predicted membrane proteins Evidence at protein level HPA044402 Supported Endoplasmic reticulum Expressed in all Expressed in all cerebral cortex: 43.1 Expressed in all +RAB11FIP1 FLJ22524, FLJ22622, Rab11-FIP1, RCP ENSG00000156675 RAB11 family interacting protein 1 8 37858618-37899467 Predicted intracellular proteins Evidence at protein level CAB017037, HPA023904, HPA024010, HPA025960 Enhanced Enhanced Vesicles Renal cancer:1.14e-6 (favourable), Head and neck cancer:6.61e-4 (favourable) Mixed Expressed in all lung: 111.7 Cell line enhanced K-562: 65.6 +UNC5D KIAA1777, Unc5h4 ENSG00000156687 Unc-5 netrin receptor D 8 35235457-35796550 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042940 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 9.2;duodenum: 6.1;prostate: 8.3 cervix, uterine: 3.4 Cell line enhanced HEK 293: 2.7;NTERA-2: 9.6;SH-SY5Y: 3.5;U-251 MG: 2.5 +GLYATL2 BXMAS2-10, MGC24009 ENSG00000156689 Glycine-N-acyltransferase like 2 11 58834065-58904215 Enzymes, Predicted intracellular proteins Evidence at protein level HPA060292, HPA065454 Uncertain Approved Mitochondria Endometrial cancer:9.05e-7 (favourable) Tissue enhanced Group enriched 6 breast: 14.3;cervix, uterine: 27.5;gallbladder: 11.0 salivary gland: 3.0 Cell line enhanced BJ hTERT+: 4.1;HAP1: 5.9;SK-BR-3: 10.2;U-2197: 6.0 +UTP14A NY-CO-16, SDCCAG16 ENSG00000156697 UTP14A small subunit processome component X 129906121-129929761 Predicted intracellular proteins Evidence at protein level HPA047217, HPA054023 Uncertain Supported Nucleoli
Cytosol Renal cancer:8.12e-8 (unfavourable), Head and neck cancer:7.67e-4 (unfavourable) Expressed in all Expressed in all endometrium: 18.5 Expressed in all +AIFM1 AIF, CMTX4, NAMSD, PDCD8 ENSG00000156709 Apoptosis inducing factor mitochondria associated 1 X 130129362-130165887 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB003764, HPA030611 Enhanced Renal cancer:4.42e-10 (favourable) Expressed in all Expressed in all kidney: 158.1 Expressed in all +MAPK13 p38delta, PRKM13, SAPK4 ENSG00000156711 Mitogen-activated protein kinase 13 6 36127809-36144524 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007667, CAB025854 Enhanced Approved Nucleus
Nucleoli
Cytosol Renal cancer:9.00e-4 (favourable) Expressed in all Mixed skin: 93.7 Cell line enhanced HBEC3-KT: 107.0 +BAG4 SODD ENSG00000156735 BCL2 associated athanogene 4 8 38176533-38213301 Predicted intracellular proteins Evidence at protein level CAB013716, HPA018951 Approved Expressed in all Expressed in all cerebral cortex: 27.1 Expressed in all +MS4A1 B1, Bp35, CD20, MS4A2 ENSG00000156738 Membrane spanning 4-domains A1 11 60455752-60470760 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB000015, HPA014341, HPA014391 Enhanced Supported Plasma membrane Breast cancer:4.34e-5 (favourable) Mixed Group enriched 15 appendix: 240.0;lymph node: 770.3;spleen: 468.8;tonsil: 789.8 urinary bladder: 38.3 Group enriched 19 Daudi: 534.8;U-698: 258.0 +TBC1D31 Gm85, MGC21654, WDR67 ENSG00000156787 TBC1 domain family member 31 8 123041968-123152153 Predicted intracellular proteins Evidence at protein level HPA023710 Approved Approved Centrosome Lung cancer:2.91e-4 (unfavourable) Mixed Mixed testis: 8.4 Expressed in all +WDYHV1 C8orf32, FLJ10204 ENSG00000156795 WDYHV motif containing 1 8 123416725-123467230 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024823, HPA053680 Approved Supported Nucleoplasm
Vesicles Endometrial cancer:4.93e-5 (unfavourable), Liver cancer:3.47e-4 (unfavourable) Expressed in all Expressed in all testis: 18.5 Expressed in all +ATAD2 CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000 ENSG00000156802 ATPase family, AAA domain containing 2 8 123319850-123416350 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029424, CAB056158 Enhanced Enhanced Nucleoplasm Renal cancer:8.33e-15 (unfavourable), Endometrial cancer:2.04e-4 (unfavourable) Expressed in all Mixed testis: 34.4 Expressed in all +FBXO32 ATROGIN1, Fbx32, MAFbx ENSG00000156804 F-box protein 32 8 123497889-123541206 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065209 Supported Nucleoplasm
Cytosol Renal cancer:6.73e-4 (unfavourable) Expressed in all Tissue enhanced smooth muscle: 146.8 skeletal muscle: 88.6 Group enriched 6 HDLM-2: 163.0;U-251 MG: 43.0 +NSMCE2 C8orf36, FLJ32440, MMS21, NSE2, ZMIZ7 ENSG00000156831 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase 8 125091679-125367120 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051614, HPA065734 Supported Supported Nucleus
Nuclear bodies Liver cancer:7.54e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 30.0 Expressed in all +ZNF689 FLJ90415 ENSG00000156853 Zinc finger protein 689 16 30602558-30624012 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054095, HPA055385 Approved Approved Nucleus
Nucleoli fibrillar center Pancreatic cancer:9.89e-4 (favourable) Expressed in all Expressed in all testis: 35.4 Expressed in all +PRR14 MGC3121 ENSG00000156858 Proline rich 14 16 30650717-30656440 Predicted intracellular proteins Evidence at protein level HPA052022, HPA060265 Uncertain Approved Nucleoplasm Cervical cancer:8.19e-5 (favourable) Expressed in all Expressed in all spleen: 20.0 Expressed in all +FBRS FBS, FBS1, FLJ11618 ENSG00000156860 Fibrosin 16 30658431-30670814 Predicted intracellular proteins Evidence at protein level HPA044117 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 78.0 Expressed in all +FRRS1 SDFR2, SDR2 ENSG00000156869 Ferric chelate reductase 1 1 99708703-99766631 Predicted membrane proteins Evidence at protein level HPA017883 Approved Renal cancer:6.53e-4 (unfavourable) Expressed in all Mixed placenta: 15.8 Cell line enhanced HEL: 33.4 +PHKG2 ENSG00000156873 Phosphorylase kinase catalytic subunit gamma 2 16 30748270-30761176 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA065618, HPA068751 Supported Cytosol Lung cancer:1.90e-4 (favourable), Cervical cancer:7.90e-4 (favourable), Pancreatic cancer:8.02e-4 (favourable), Colorectal cancer:9.92e-4 (unfavourable) Expressed in all Expressed in all testis: 149.4 Expressed in all +MFSD14A DKFZP564L0864, HIAT1 ENSG00000156875 Major facilitator superfamily domain containing 14A 1 100038097-100083377 Predicted membrane proteins Evidence at protein level HPA073681 Approved Vesicles Liver cancer:2.08e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 195.0 Expressed in all +SASS6 DKFZp761A078, FLJ22097, SAS-6, SAS6 ENSG00000156876 SAS-6 centriolar assembly protein 1 100083563-100132955 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028187 Uncertain Supported Microtubule organizing center
Cytosol Expressed in all Mixed testis: 13.3 Mixed +COX6A2 ENSG00000156885 Cytochrome c oxidase subunit 6A2 16 31427731-31428428 Predicted intracellular proteins, Transporters Evidence at protein level Group enriched Group enriched 23 heart muscle: 687.3;skeletal muscle: 1846.8 esophagus: 54.9 Cell line enhanced HSkMC: 1.6;SiHa: 1.0;U-266/84: 7.0 +ITGAD ADB2, CD11d ENSG00000156886 Integrin subunit alpha D 16 31393312-31426505 CD markers, Predicted membrane proteins Evidence at protein level HPA026786 Uncertain Mixed Tissue enriched 5 spleen: 27.9 lymph node: 5.1 Not detected +ADGRG4 GPR112, PGR17, RP1-299I16 ENSG00000156920 Adhesion G protein-coupled receptor G4 X 136300963-136416888 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA035324 Uncertain Not detected Tissue enhanced duodenum: 2.5;small intestine: 1.7 fallopian tube: 0.5 Not detected +ZIC3 HTX, HTX1, ZNF203 ENSG00000156925 Zic family member 3 X 137566142-137577691 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052936, HPA069523 Approved Supported Nucleoplasm Tissue enriched Group enriched 12 cerebral cortex: 1.6;testis: 1.3 bone marrow,skin: 0.1 Group enriched 38 AF22: 39.4;NTERA-2: 44.7 +MALSU1 C7orf30, mtRsfA ENSG00000156928 Mitochondrial assembly of ribosomal large subunit 1 7 23298739-23311729 Predicted secreted proteins Evidence at protein level HPA020487, HPA052210 Approved Enhanced Mitochondria Head and neck cancer:9.71e-4 (unfavourable) Expressed in all Mixed thyroid gland: 5.2 Expressed in all +VPS8 FLJ32099, KIAA0804 ENSG00000156931 VPS8, CORVET complex subunit 3 184812143-185052614 Predicted intracellular proteins Evidence at protein level HPA036871 Uncertain Approved Plasma membrane
Cytosol Expressed in all Expressed in all testis: 31.2 Expressed in all +GALK2 GK2 ENSG00000156958 Galactokinase 2 15 49155656-49367869 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043564, HPA048267 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.88e-5 (favourable), Endometrial cancer:7.31e-4 (favourable) Expressed in all Expressed in all kidney: 31.8 Expressed in all +LHFPL4 ENSG00000156959 Lipoma HMGIC fusion partner-like 4 3 9498361-9553802 Predicted membrane proteins Evidence at protein level HPA041421 Uncertain Approved Nucleus
Golgi apparatus Group enriched Tissue enriched 9 cerebral cortex: 23.1 adrenal gland: 2.6 Cell line enhanced NTERA-2: 4.4;SCLC-21H: 11.9;SH-SY5Y: 13.4;U-266/84: 7.9;WM-115: 3.9 +B3GNT7 beta3GnT7 ENSG00000156966 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 2 231395543-231401164 Predicted secreted proteins Evidence at protein level HPA035625, HPA035626 Enhanced Thyroid cancer:6.00e-4 (favourable) Expressed in all Tissue enhanced rectum: 72.7 colon: 54.1 Cell line enhanced CAPAN-2: 16.3;HEL: 13.4;THP-1: 8.9;WM-115: 22.2 +MPV17L FLJ39599, MLPH1, MLPH2, MPV17L1 ENSG00000156968 MPV17 mitochondrial inner membrane protein like 16 15395754-15413268 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041180 Uncertain Supported Vesicles Renal cancer:1.48e-11 (favourable) Mixed Mixed breast: 10.3 Cell line enhanced HMC-1: 35.5 +BUB1B Bub1A, BUBR1, MAD3L, SSK1 ENSG00000156970 BUB1 mitotic checkpoint serine/threonine kinase B 15 40161023-40221136 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA008419 Supported Cytosol Liver cancer:7.43e-6 (unfavourable), Pancreatic cancer:1.79e-4 (unfavourable), Lung cancer:3.56e-4 (unfavourable) Expressed in all Tissue enhanced testis: 40.3 lymph node: 14.9 Mixed +PDE6D JBTS22 ENSG00000156973 Phosphodiesterase 6D 2 231732425-231786272 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037433, HPA037434 Uncertain Renal cancer:4.02e-5 (unfavourable), Urothelial cancer:4.97e-4 (favourable) Expressed in all Expressed in all testis: 48.3 Expressed in all +EIF4A2 BM-010, DDX2B, EIF4A, EIF4F ENSG00000156976 Eukaryotic translation initiation factor 4A2 3 186783205-186789900 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011690, HPA068286 Uncertain Approved Cytosol Expressed in all Expressed in all ovary: 726.0 Expressed in all +BRPF1 BR140 ENSG00000156983 Bromodomain and PHD finger containing 1 3 9731729-9748018 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003359 Enhanced Approved Plasma membrane
Cytosol Liver cancer:3.20e-5 (unfavourable), Prostate cancer:5.28e-4 (unfavourable) Expressed in all Expressed in all testis: 26.3 Expressed in all +RPUSD3 MGC29784 ENSG00000156990 RNA pseudouridylate synthase domain containing 3 3 9837849-9844602 Predicted intracellular proteins Evidence at protein level HPA037551, HPA037552 Uncertain Approved Nucleus Liver cancer:1.73e-5 (unfavourable) Expressed in all Expressed in all testis: 54.0 Expressed in all +SST SMST ENSG00000157005 Somatostatin 3 187668906-187670399 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000075, HPA019472, CAB034105 Enhanced Supported Endometrial cancer:1.93e-5 (unfavourable) Group enriched Tissue enhanced cerebral cortex: 211.9;duodenum: 376.3;stomach: 305.7 small intestine: 142.4 Group enriched 5 EFO-21: 20.9;U-2 OS: 42.8 +TATDN2 KIAA0218 ENSG00000157014 TatD DNase domain containing 2 3 10248023-10281218 Predicted intracellular proteins Evidence at protein level HPA036822, HPA058001 Approved Supported Nucleus
Nuclear speckles
Cytosol Pancreatic cancer:4.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 38.3 Expressed in all +GHRL ghrelin, MTLRP, obestatin ENSG00000157017 Ghrelin and obestatin prepropeptide 3 10285675-10292947 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA014246, CAB022731 Enhanced Mixed Tissue enriched 8 stomach: 156.2 duodenum: 19.0 Cell line enhanced Karpas-707: 10.4 +SEC13 D3S1231E, npp-20, SEC13L1, SEC13R ENSG00000157020 SEC13 homolog, nuclear pore and COPII coat complex component 3 10293131-10321178 Predicted intracellular proteins, Transporters Evidence at protein level HPA035292, HPA057943 Approved Supported Nucleoplasm
Vesicles Liver cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 120.0 Expressed in all +EXOG ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGL-b ENSG00000157036 Exo/endonuclease G 3 38496127-38542161 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012531 Enhanced Pancreatic cancer:1.92e-5 (favourable), Prostate cancer:4.90e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 7.4 Expressed in all +NTAN1 ENSG00000157045 N-terminal asparagine amidase 16 15037853-15056079 Predicted intracellular proteins Evidence at protein level HPA051418 Approved Nucleoplasm
Golgi apparatus Glioma:8.85e-4 (unfavourable), Stomach cancer:9.07e-4 (unfavourable) Expressed in all Expressed in all epididymis: 20.4 Expressed in all +SHCBP1L C1orf14 ENSG00000157060 SHC binding and spindle associated 1 like 1 182899865-182953525 Predicted intracellular proteins Evidence at protein level HPA036124, HPA036125, HPA064821 Enhanced Tissue enhanced Tissue enriched 989 testis: 98.9 all non-specific tissues: 0.0 Not detected +NMNAT2 C1orf15, KIAA0479, PNAT2 ENSG00000157064 Nicotinamide nucleotide adenylyltransferase 2 1 183248237-183418602 Enzymes, Predicted intracellular proteins Evidence at protein level HPA061714 Enhanced Mixed Tissue enriched 6 cerebral cortex: 73.5 testis: 13.3 Cell line enhanced SCLC-21H: 91.4;U-2197: 42.4;U-87 MG: 34.4 +ZFYVE9 MADHIP, PPP1R173, SARA, SMADIP ENSG00000157077 Zinc finger FYVE-type containing 9 1 52142094-52346686 Predicted intracellular proteins Evidence at protein level CAB017702, HPA065852, HPA065862 Approved Enhanced Vesicles
Cytosol Expressed in all Mixed parathyroid gland: 45.2 Mixed +ATP2B2 PMCA2 ENSG00000157087 ATPase plasma membrane Ca2+ transporting 2 3 10324023-10708031 Enzymes, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB005606 Enhanced Tissue enhanced Tissue enriched 7 cerebral cortex: 64.7 salivary gland: 9.7 Group enriched 7 EFO-21: 3.0;RPMI-8226: 5.4;SCLC-21H: 4.2;SH-SY5Y: 1.2 +LYZL4 LYC4, MGC26768 ENSG00000157093 Lysozyme like 4 3 42397078-42410600 Predicted secreted proteins Evidence at protein level HPA038806 Approved Not detected Tissue enriched 58 testis: 43.8 cerebral cortex: 0.7 Not detected +SLC6A1 GABATHG, GABATR, GAT1 ENSG00000157103 Solute carrier family 6 member 1 3 10992724-11039247 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA013341, CAB022293 Enhanced Uncertain Mitochondria Renal cancer:5.05e-6 (unfavourable), Liver cancer:3.20e-4 (favourable) Group enriched Group enriched 5 cerebral cortex: 119.4;liver: 50.4 parathyroid gland: 16.0 Not detected +SMG1 ATX, KIAA0421, LIP ENSG00000157106 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 16 18804853-18926454 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006870, HPA031623, HPA073972 Approved Supported Nucleoplasm Expressed in all Expressed in all skin: 50.1 Expressed in all +FCHO2 ENSG00000157107 FCH domain only 2 5 72955981-73090522 Predicted intracellular proteins Evidence at protein level HPA037685, HPA037686, HPA077850 Enhanced Approved Vesicles
Centrosome
Cytosol Renal cancer:7.00e-5 (favourable) Expressed in all Expressed in all thyroid gland: 39.6 Mixed +RBPMS HERMES ENSG00000157110 RNA binding protein with multiple splicing 8 30384479-30572261 Predicted intracellular proteins Evidence at protein level HPA056999 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Mixed seminal vesicle: 267.6 Cell line enhanced ASC diff: 222.6 +TMEM171 PRP2 ENSG00000157111 Transmembrane protein 171 5 73120292-73131817 Predicted membrane proteins Evidence at protein level HPA042308 Approved Renal cancer:3.93e-10 (favourable) Mixed Tissue enhanced colon: 32.4;rectum: 32.3;thyroid gland: 47.1 duodenum: 26.3 Cell line enhanced LHCN-M2: 48.9;WM-115: 161.7 +KLHL40 KBTBD5, NEM8, SRYP ENSG00000157119 Kelch like family member 40 3 42685519-42692544 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024463, HPA052201 Enhanced Tissue enhanced Tissue enriched 14 skeletal muscle: 61.0 prostate: 4.3 Not detected +C8A ENSG00000157131 Complement C8 alpha chain 1 56854806-56918221 Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level Tissue enriched Tissue enriched 63 liver: 328.8 gallbladder: 5.2 Not detected +TIMP4 ENSG00000157150 TIMP metallopeptidase inhibitor 4 3 12153051-12159351 Plasma proteins, Predicted secreted proteins Evidence at transcript level Tissue enriched Tissue enriched 5 adipose tissue: 138.8 cerebral cortex: 27.5 Cell line enhanced ASC diff: 99.5;HSkMC: 45.7;NTERA-2: 37.0;U-87 MG: 36.7 +SYN2 SYNII, SYNIIa, SYNIIb ENSG00000157152 Synapsin II 3 12004402-12191400 Predicted intracellular proteins Evidence at protein level HPA037012, CAB079005 Supported Approved Nucleoplasm Tissue enhanced Tissue enriched 29 cerebral cortex: 200.0 testis: 6.8 Cell line enhanced HMC-1: 4.4;NTERA-2: 4.3;SCLC-21H: 4.0;SH-SY5Y: 14.4 +NRG1 GGF, HGL, HRG, NDF, NRG1-IT2 ENSG00000157168 Neuregulin 1 8 31639386-32767959 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010964 Uncertain Approved Nucleoplasm Tissue enhanced Mixed thyroid gland: 20.0 Cell line enhanced A549: 130.4;hTEC/SVTERT24-B: 101.2 +C1orf27 FLJ20505, odr-4, TTG1 ENSG00000157181 Chromosome 1 open reading frame 27 1 186375838-186421378 Predicted membrane proteins Evidence at protein level HPA015988, HPA031352 Uncertain Approved Nucleoplasm
Plasma membrane Ovarian cancer:9.92e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 76.3 Expressed in all +CPT2 CPT1, CPTASE ENSG00000157184 Carnitine palmitoyltransferase 2 1 53196429-53214197 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028201, HPA028202, HPA028214 Enhanced Supported Nucleoplasm
Nucleoli
Mitochondria Renal cancer:1.46e-12 (favourable), Colorectal cancer:5.27e-4 (favourable) Expressed in all Expressed in all liver: 25.9 Expressed in all +NECAP2 FLJ10420 ENSG00000157191 NECAP endocytosis associated 2 1 16440672-16460078 Predicted intracellular proteins Evidence at protein level HPA028077 Approved Approved Endoplasmic reticulum Liver cancer:6.13e-4 (unfavourable) Expressed in all Expressed in all spleen: 86.0 Expressed in all +LRP8 APOER2, HSZ75190, LRP-8, MCI1 ENSG00000157193 LDL receptor related protein 8 1 53242364-53328070 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA073031 Enhanced Endometrial cancer:3.46e-6 (unfavourable), Lung cancer:7.02e-4 (unfavourable) Mixed Group enriched 7 cerebral cortex: 25.2;testis: 46.9;thyroid gland: 87.5 appendix: 7.7 Expressed in all +CDCP2 ENSG00000157211 CUB domain containing protein 2 1 54132968-54153770 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA031143 Uncertain Not detected Not detected breast,cervix, uterine,spleen: 0.1 Not detected +PAXIP1 CAGF28, CAGF29, PAXIP1L, PTIP, TNRC2 ENSG00000157212 PAX interacting protein 1 7 154943687-155003084 Predicted intracellular proteins Evidence at protein level HPA006694, HPA016950 Enhanced Approved Nucleoplasm
Vesicles Expressed in all Mixed testis: 16.2 Expressed in all +STEAP2 IPCA-1, PCANAP1, STAMP1, STMP ENSG00000157214 STEAP2 metalloreductase 7 90167590-90238137 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA029115, HPA055603 Uncertain Supported Vesicles Tissue enriched Tissue enriched 11 prostate: 208.0 parathyroid gland: 18.7 Cell line enhanced A549: 20.3;CAPAN-2: 42.2;U-138 MG: 26.9 +SSBP3 CSDP, FLJ10355, SSDP, SSDP1 ENSG00000157216 Single stranded DNA binding protein 3 1 54225432-54413479 Predicted intracellular proteins Evidence at protein level Cervical cancer:2.48e-9 (favourable), Endometrial cancer:2.10e-4 (unfavourable) Expressed in all Expressed in all ovary: 117.5 Expressed in all +HTR5A 5-HT5A ENSG00000157219 5-hydroxytryptamine receptor 5A 7 155070324-155085749 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level CAB017467 Approved Not detected Tissue enriched 11 cerebral cortex: 8.6 testis: 0.7 Not detected +CLDN12 ENSG00000157224 Claudin 12 7 90383721-90513402 Predicted membrane proteins Evidence at protein level HPA026945 Approved Cervical cancer:6.36e-4 (unfavourable) Expressed in all Expressed in all prostate: 40.5 Mixed +MMP14 MT1-MMP ENSG00000157227 Matrix metallopeptidase 14 14 22836557-22849027 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009918, HPA051432 Approved Approved Intermediate filaments
Cytosol Renal cancer:1.34e-4 (unfavourable), Ovarian cancer:9.48e-4 (unfavourable) Expressed in all Mixed endometrium: 236.6 Cell line enhanced HHSteC: 664.7 +FZD1 DKFZp564G072 ENSG00000157240 Frizzled class receptor 1 7 91264364-91271326 Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB013008 Approved Supported Plasma membrane Renal cancer:8.87e-7 (favourable) Expressed in all Mixed thyroid gland: 32.4 Mixed +GATAD1 FLJ22489, ODAG, RG083M05.2 ENSG00000157259 GATA zinc finger domain containing 1 7 92447453-92458836 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006105, HPA072785 Supported Nucleus Expressed in all Expressed in all thyroid gland: 42.3 Expressed in all +SUSD3 MGC26847 ENSG00000157303 Sushi domain containing 3 9 93058688-93085138 Predicted membrane proteins Evidence at protein level HPA042310 Uncertain Approved Nucleus Breast cancer:5.13e-4 (favourable) Expressed in all Tissue enhanced testis: 91.6 lymph node: 66.4 Cell line enhanced Daudi: 107.9;NB-4: 49.1;RPMI-8226: 56.9 +TMED6 MGC23911, p24g5, p24gamma5 ENSG00000157315 Transmembrane p24 trafficking protein 6 16 69343248-69351809 Predicted membrane proteins Evidence at protein level HPA012532 Approved Endometrial cancer:7.74e-5 (favourable) Mixed Tissue enhanced fallopian tube: 35.3;pancreas: 61.2;stomach: 37.5 epididymis: 21.3 Cell line enhanced Hep G2: 10.1 +CLEC18A MRCL ENSG00000157322 C-type lectin domain family 18 member A 16 69950705-69964452 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048976 Uncertain Tissue enriched Group enriched 7 kidney: 15.7;testis: 3.7 adrenal gland: 1.3 Not detected +DHRS4 FLJ11008, humNRDR, SCAD-SRL, SDR-SRL, SDR25C2 ENSG00000157326 Dehydrogenase/reductase 4 14 23953586-23969279 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023972 Uncertain Approved Nuclear membrane
Vesicles Renal cancer:4.55e-6 (favourable) Expressed in all Expressed in all kidney: 149.0 Mixed +C1orf158 MGC35194 ENSG00000157330 Chromosome 1 open reading frame 158 1 12746215-12763699 Predicted intracellular proteins Evidence at transcript level HPA028396 Uncertain Cytosol Group enriched Group enriched 15 fallopian tube: 42.6;testis: 47.5 lung: 2.9 Not detected +CLEC18C MGC34761 ENSG00000157335 C-type lectin domain family 18 member C 16 70173322-70187361 Predicted secreted proteins Evidence at transcript level HPA048976 Uncertain Tissue enriched Group enriched 23 kidney: 11.4;testis: 3.6 duodenum: 0.3 Not detected +ARMC12 C6orf81, FLJ25390 ENSG00000157343 Armadillo repeat containing 12 6 35737032-35749079 Predicted intracellular proteins Evidence at protein level HPA030895 Approved Nucleoplasm
Plasma membrane Mixed Tissue enriched 8 testis: 63.2 epididymis: 7.5 Cell line enhanced HSkMC: 4.9;MOLT-4: 4.0 +DDX19B DBP5, DDX19 ENSG00000157349 DEAD-box helicase 19B 16 70289663-70335283 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB037229, CAB037284, HPA046380, HPA066668 Approved Uncertain Nucleoplasm Expressed in all Expressed in all testis: 82.8 Mixed +ST3GAL2 SIAT4B, ST3GalA.2, ST3GALII ENSG00000157350 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 16 70375978-70439237 Enzymes, Predicted membrane proteins Evidence at protein level HPA017270 Approved Approved Vesicles Renal cancer:3.34e-6 (unfavourable), Pancreatic cancer:2.33e-4 (favourable), Liver cancer:2.79e-4 (unfavourable) Expressed in all Mixed appendix: 15.2 Mixed +FUK FLJ39408 ENSG00000157353 Fucokinase 16 70454421-70480274 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041971 Approved Approved Vesicles Urothelial cancer:8.38e-4 (favourable), Renal cancer:8.91e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 13.9 Mixed +IL34 C16orf77, IL-34, MGC34647 ENSG00000157368 Interleukin 34 16 70579895-70660682 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:3.52e-8 (unfavourable), Cervical cancer:7.41e-4 (favourable), Head and neck cancer:9.69e-4 (favourable) Expressed in all Tissue enhanced skin: 58.0;spleen: 145.6 cerebral cortex: 20.8 Cell line enhanced NTERA-2: 5.5;U-138 MG: 3.5 +DHRS1 FLJ25430, MGC20204, SDR19C1 ENSG00000157379 Dehydrogenase/reductase 1 14 24290598-24299833 Predicted intracellular proteins Evidence at protein level HPA000599 Approved Approved Nucleus
Centrosome
Cytosol Liver cancer:1.18e-5 (favourable), Lung cancer:6.83e-4 (favourable) Expressed in all Expressed in all esophagus: 78.3 Expressed in all +CACNA1D CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2 ENSG00000157388 Calcium voltage-gated channel subunit alpha1 D 3 53328963-53813733 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA020215 Uncertain Approved Nuclear membrane Renal cancer:8.34e-8 (favourable) Mixed Mixed fallopian tube: 13.5 Cell line enhanced HMC-1: 19.6;RPMI-8226: 38.4;SK-BR-3: 7.4 +ARSE CDPX, CDPX1 ENSG00000157399 Arylsulfatase E (chondrodysplasia punctata 1) X 2934632-2968310 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA060518, HPA070651 Approved Supported Golgi apparatus Colorectal cancer:8.95e-4 (favourable) Mixed Tissue enhanced kidney: 41.3;liver: 49.3 pancreas: 23.9 Cell line enhanced A549: 65.1;CACO-2: 37.1;Hep G2: 46.2;NTERA-2: 32.8 +KIT C-Kit, CD117, PBT, SCFR ENSG00000157404 KIT proto-oncogene receptor tyrosine kinase 4 54657918-54740715 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level CAB003288, HPA004471, CAB068253, CAB072867, HPA073252 Enhanced Supported Supported Plasma membrane Renal cancer:5.63e-4 (favourable) Mixed Tissue enhanced breast: 133.6 thyroid gland: 78.7 Group enriched 14 HEL: 220.1;HMC-1: 434.1 +HYDIN CILD5, DKFZp434D0513, KIAA1864, PPP1R31 ENSG00000157423 HYDIN, axonemal central pair apparatus protein 16 70807378-71230722 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA067155, HPA074129 Enhanced Approved Plasma membrane
Cytosol Not detected Tissue enhanced fallopian tube: 9.1;parathyroid gland: 5.4;testis: 6.4 epididymis: 2.6 Cell line enhanced RPTEC TERT1: 2.1;SiHa: 6.4 +AASDH ACSF4, LYS2, NRPS998 ENSG00000157426 Aminoadipate-semialdehyde dehydrogenase 4 56338287-56387508 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036472, HPA036473 Approved Expressed in all Mixed parathyroid gland: 15.1 Expressed in all +ZNF19 KOX12, MGC51021 ENSG00000157429 Zinc finger protein 19 16 71464555-71565089 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA063685 Approved Approved Mitochondria Mixed Expressed in all testis: 29.2 Mixed +CACNA2D3 HSA272268 ENSG00000157445 Calcium voltage-gated channel auxiliary subunit alpha2delta 3 3 54122547-55074557 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA030849, HPA030850 Uncertain Nucleus
Cytosol Mixed Tissue enhanced cerebral cortex: 16.2 adrenal gland: 5.4 Cell line enhanced BJ hTERT+: 3.3;HAP1: 1.9;HeLa: 6.3 +RNF111 ARK, Arkadia, DKFZP761D081, FLJ38008 ENSG00000157450 Ring finger protein 111 15 58865175-59097419 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038576, HPA038577 Enhanced Supported Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland: 22.9 Expressed in all +CCNB2 HsT17299 ENSG00000157456 Cyclin B2 15 59105078-59125045 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA008873, CAB009575 Enhanced Enhanced Golgi apparatus
Cytosol Renal cancer:0.00e+0 (unfavourable), Pancreatic cancer:1.74e-5 (unfavourable), Melanoma:3.21e-5 (unfavourable), Liver cancer:2.83e-4 (unfavourable), Lung cancer:4.63e-4 (unfavourable) Expressed in all Tissue enhanced testis: 122.6 bone marrow: 44.7 Expressed in all +FAM81A MGC26690 ENSG00000157470 Family with sequence similarity 81 member A 15 59372693-59523549 Predicted intracellular proteins Evidence at protein level HPA001847, HPA065797 Enhanced Approved Nucleoplasm
Cytosol Mixed Tissue enhanced cerebral cortex: 33.3 fallopian tube: 9.9 Cell line enhanced Daudi: 47.3 +MYO1E HuncM-IC, MGC104638, MYO1C ENSG00000157483 Myosin IE 15 59132434-59372900 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023886 Approved Lung cancer:1.57e-6 (unfavourable), Endometrial cancer:4.19e-4 (favourable), Pancreatic cancer:7.99e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 67.0 Mixed +APPL1 APPL ENSG00000157500 Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 3 57227737-57273468 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA011138, HPA073477 Approved Uncertain Mitotic spindle
Centrosome Renal cancer:7.26e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 44.1 Expressed in all +MUM1L1 FLJ33516 ENSG00000157502 MUM1 like 1 X 106168305-106208956 Predicted intracellular proteins Evidence at protein level HPA000168, HPA020464 Enhanced Thyroid cancer:5.95e-4 (unfavourable) Mixed Tissue enriched 7 ovary: 226.8 testis: 33.9 Cell line enhanced AF22: 2.9;HSkMC: 2.1;LHCN-M2: 4.6;NTERA-2: 2.1;T-47d: 1.7 +AFAP1L1 FLJ36748 ENSG00000157510 Actin filament associated protein 1 like 1 5 149271871-149341802 Predicted intracellular proteins Evidence at protein level Colorectal cancer:2.84e-4 (unfavourable) Expressed in all Mixed adipose tissue: 29.8 Cell line enhanced BEWO: 57.1;TIME: 37.4;WM-115: 105.1 +TSC22D3 DIP, DSIPI, GILZ, hDIP, TSC-22R ENSG00000157514 TSC22 domain family member 3 X 107713221-107777342 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001916, CAB034364 Approved Approved Nuclear speckles
Golgi apparatus
Cytosol Endometrial cancer:2.43e-4 (unfavourable) Expressed in all Expressed in all breast: 548.3 Cell line enhanced ASC diff: 261.1;HHSteC: 527.6;hTCEpi: 413.6;Karpas-707: 261.7 +DSCR3 DCRA ENSG00000157538 DSCR3 arrestin fold containing 21 37223420-37267919 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023288 Uncertain Approved Mitochondria Renal cancer:8.54e-4 (favourable) Expressed in all Expressed in all kidney: 32.2 Expressed in all +DYRK1A DYRK, DYRK1, MNBH ENSG00000157540 Dual specificity tyrosine phosphorylation regulated kinase 1A 21 37365790-37517450 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015323, HPA015810 Approved Approved Nucleoli fibrillar center
Cytosol Expressed in all Expressed in all parathyroid gland: 61.3 Expressed in all +KCNJ6 BIR1, GIRK2, hiGIRK2, KATP2, KCNJ7, Kir3.2 ENSG00000157542 Potassium voltage-gated channel subfamily J member 6 21 37607376-37916446 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Not detected Tissue enriched 9 cerebral cortex: 2.6 spleen,stomach,testis: 0.2 Cell line enhanced LHCN-M2: 7.1;TIME: 1.8 +KCNJ15 IRKK, Kir1.3, Kir4.2 ENSG00000157551 Potassium voltage-gated channel subfamily J member 15 21 38157034-38307357 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA016702 Approved Approved Vesicles
Plasma membrane
Cytosol Renal cancer:4.09e-10 (favourable), Urothelial cancer:1.95e-4 (favourable) Tissue enhanced Tissue enhanced kidney: 261.3;thyroid gland: 216.3 lung: 63.4 Cell line enhanced ASC TERT1: 48.4;HBEC3-KT: 50.0;RPTEC TERT1: 51.4;RT4: 65.6 +ERG erg-3, p55 ENSG00000157554 ERG, ETS transcription factor 21 38380027-38661780 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB018377, HPA046598 Approved Approved Nucleoplasm
Cytosol Cervical cancer:6.18e-6 (unfavourable), Renal cancer:3.94e-4 (unfavourable) Expressed in all Expressed in all spleen: 36.8 Cell line enhanced HUVEC TERT2: 115.5;MOLT-4: 38.1;REH: 138.0;TIME: 92.4 +ETS2 ENSG00000157557 ETS proto-oncogene 2, transcription factor 21 38805307-38824955 Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level HPA003176 Enhanced Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all spleen: 252.7 Cell line enhanced HEL: 249.9 +TSPAN18 TSPAN ENSG00000157570 Tetraspanin 18 11 44726465-44932421 Predicted membrane proteins Evidence at protein level Expressed in all Mixed smooth muscle: 69.3 Cell line enhanced AF22: 36.4;CAPAN-2: 54.1;HDLM-2: 47.8;NTERA-2: 34.7;RH-30: 37.3;SCLC-21H: 38.6;SH-SY5Y: 39.5 +LCA5L C21orf13, MGC33295 ENSG00000157578 LCA5L, lebercilin like 21 39405844-39445805 Predicted intracellular proteins Evidence at protein level HPA019790, HPA032010 Enhanced Uncertain Nucleoplasm
Cytosol Mixed Tissue enriched 17 testis: 201.6 fallopian tube: 12.2 Mixed +SLC35B2 UGTrel4 ENSG00000157593 Solute carrier family 35 member B2 6 44254096-44257890 Predicted membrane proteins, Transporters Evidence at protein level HPA029638 Approved Approved Vesicles Liver cancer:8.59e-5 (unfavourable), Prostate cancer:6.07e-4 (favourable), Breast cancer:7.90e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 59.2 Expressed in all +TMEM164 FLJ22679, RP13-360B22.2 ENSG00000157600 Transmembrane protein 164 X 110002631-110182734 Predicted membrane proteins Evidence at protein level HPA038784 Approved Approved Vesicles
Cell Junctions Liver cancer:8.17e-6 (unfavourable), Stomach cancer:3.14e-4 (favourable) Expressed in all Expressed in all lung: 26.7 Expressed in all +MX1 IFI-78K, MxA ENSG00000157601 MX dynamin like GTPase 1 21 41420304-41459214 Predicted intracellular proteins Evidence at protein level HPA030917, HPA030918, HPA049724 Approved Approved Supported Nuclear membrane
Cytosol Renal cancer:1.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 114.7 Cell line enhanced BJ hTERT+ SV40 Large T+: 786.8;BJ hTERT+ SV40 Large T+ RasG12V: 735.0;SK-MEL-30: 205.0 +CREB3L1 OASIS ENSG00000157613 CAMP responsive element binding protein 3 like 1 11 46277661-46321422 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA024069, CAB026151 Enhanced Approved Plasma membrane
Cytosol Renal cancer:2.97e-4 (unfavourable), Endometrial cancer:3.92e-4 (favourable), Thyroid cancer:8.59e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 66.0 Cell line enhanced fHDF/TERT166: 248.2 +C2CD2 C21orf25, C21orf258, DKFZP586F0422, TMEM24L ENSG00000157617 C2 calcium dependent domain containing 2 21 41885112-41953890 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030922, HPA030924 Enhanced Approved Nucleoplasm Renal cancer:7.68e-5 (unfavourable) Expressed in all Tissue enhanced adrenal gland: 110.0 spleen: 46.2 Cell line enhanced ASC diff: 54.3 +TAB3 MAP3K7IP3 ENSG00000157625 TGF-beta activated kinase 1 and MAP3K7 binding protein 3 X 30827442-30975084 Predicted intracellular proteins Evidence at protein level HPA034980, HPA034981 Approved Approved Nuclear speckles
Cytosol Renal cancer:8.45e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 53.6 Expressed in all +SLC38A10 MGC15523, PP1744 ENSG00000157637 Solute carrier family 38 member 10 17 81245000-81295547 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA021374, HPA023161, HPA024631 Enhanced Enhanced Golgi apparatus Renal cancer:5.34e-7 (unfavourable), Pancreatic cancer:2.92e-4 (favourable) Expressed in all Expressed in all thyroid gland: 44.6 Expressed in all +C9orf43 MGC17358 ENSG00000157653 Chromosome 9 open reading frame 43 9 113410054-113429684 Predicted intracellular proteins Evidence at protein level HPA021310 Approved Cytosol Mixed Tissue enriched 43 testis: 73.9 parathyroid gland: 1.7 Mixed +PALM2-AKAP2 ENSG00000157654 PALM2-AKAP2 readthrough 9 109780309-110172512 Predicted intracellular proteins Evidence at protein level HPA058905, HPA074153 Uncertain Not detected Tissue enhanced adipose tissue: 23.4 heart muscle: 19.7 Cell line enhanced hTEC/SVTERT24-B: 27.6;RH-30: 52.6;WM-115: 31.6 +ZNF618 KIAA1952, NEDD10 ENSG00000157657 Zinc finger protein 618 9 113876282-114056591 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023116, HPA061732 Uncertain Approved Nucleoplasm Renal cancer:5.22e-7 (favourable), Glioma:8.34e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 16.5 Mixed +DGKI DGK-IOTA ENSG00000157680 Diacylglycerol kinase iota 7 137381037-137847092 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021924 Approved Nucleoplasm Mixed Group enriched 11 cerebral cortex: 9.3;thyroid gland: 33.0 heart muscle,smooth muscle: 1.8 Cell line enhanced SCLC-21H: 7.5;U-2197: 16.4;U-87 MG: 6.3 +TMEM268 C9orf91, DKFZp547P234, FLJ38045 ENSG00000157693 Transmembrane protein 268 9 114611206-114646422 Predicted membrane proteins Evidence at transcript level HPA017199 Approved Approved Plasma membrane
Cytosol Endometrial cancer:3.61e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 22.3 Expressed in all +SVOPL MGC46715 ENSG00000157703 SVOP like 7 138594285-138701352 Predicted membrane proteins Evidence at transcript level HPA018035 Uncertain Mixed Tissue enriched 5 parathyroid gland: 14.3 fallopian tube: 2.6 Cell line enhanced HMC-1: 3.7;NTERA-2: 1.2;T-47d: 4.1 +SNX22 FLJ13952 ENSG00000157734 Sorting nexin 22 15 64151715-64157481 Predicted intracellular proteins Evidence at protein level HPA038470 Approved Approved Nucleoplasm
Vesicles Breast cancer:2.89e-5 (favourable), Thyroid cancer:2.19e-4 (favourable) Tissue enriched Tissue enhanced cerebral cortex: 16.2;thyroid gland: 14.4 lymph node: 9.0 Cell line enhanced Daudi: 13.5;SCLC-21H: 4.9 +UBN2 FLJ25778, KIAA2030 ENSG00000157741 Ubinuclein 2 7 139230356-139308236 Predicted intracellular proteins Evidence at protein level HPA019743, HPA020122, HPA020124 Uncertain Supported Nucleoplasm Head and neck cancer:4.49e-4 (favourable) Expressed in all Tissue enhanced testis: 26.4 skin: 11.8 Expressed in all +BRAF BRAF1 ENSG00000157764 B-Raf proto-oncogene, serine/threonine kinase 7 140719327-140924764 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA001328, CAB004552, HPA071048 Approved Approved Vesicles
Cytosol Expressed in all Expressed in all testis: 41.8 Expressed in all +SLC34A2 NAPI-3B ENSG00000157765 Solute carrier family 34 member 2 4 25655301-25678748 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA037989 Enhanced Tissue enhanced Tissue enriched 10 lung: 1121.1 fallopian tube: 111.8 Group enriched 76 BEWO: 31.0;EFO-21: 114.1;RPTEC TERT1: 66.5 +ACAN AGC1, CSPG1, CSPGCP, MSK16 ENSG00000157766 Aggrecan 15 88803443-88875354 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016377, HPA038241, HPA038242 Enhanced Renal cancer:1.47e-6 (unfavourable) Mixed Tissue enhanced seminal vesicle: 5.0 testis: 3.3 Cell line enriched 5 WM-115: 28.1 +PSMG3 C7orf48, MGC10911, PAC3 ENSG00000157778 Proteasome assembly chaperone 3 7 1567330-1571005 Predicted intracellular proteins Evidence at protein level HPA023876 Approved Liver cancer:2.40e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 46.6 Expressed in all +CABP1 ENSG00000157782 Calcium binding protein 1 12 120640552-120667324 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051438 Uncertain Tissue enhanced Tissue enriched 7 cerebral cortex: 77.4 adipose tissue: 11.2 Cell line enhanced NTERA-2: 6.8;SCLC-21H: 3.8;U-87 MG: 8.4 +WDR19 DYF-2, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp ENSG00000157796 WD repeat domain 19 4 39182404-39285810 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039616, HPA058847 Uncertain Approved Nucleoplasm
Nuclear bodies Pancreatic cancer:2.70e-4 (favourable), Liver cancer:4.43e-4 (unfavourable), Prostate cancer:8.58e-4 (unfavourable) Expressed in all Mixed fallopian tube: 30.7 Mixed +SLC37A3 DKFZp761N0624 ENSG00000157800 Solute carrier family 37 member 3 7 140293693-140404433 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014713, HPA061841 Supported Cytosol Liver cancer:4.78e-5 (unfavourable), Cervical cancer:9.54e-4 (unfavourable) Expressed in all Expressed in all endometrium: 73.0 Mixed +AP3S2 sigma3b ENSG00000157823 Adaptor related protein complex 3 sigma 2 subunit 15 89830599-89894638 Predicted intracellular proteins Evidence at transcript level HPA049270 Uncertain Approved Vesicles Renal cancer:5.55e-16 (favourable) Expressed in all Expressed in all parathyroid gland: 77.7 Expressed in all +FMNL2 FHOD2, KIAA1902 ENSG00000157827 Formin like 2 2 152335237-152649834 Predicted intracellular proteins Evidence at protein level HPA005464 Enhanced Approved Golgi apparatus
Plasma membrane
Cytosol Liver cancer:9.04e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 137.8 placenta: 82.9 Cell line enhanced BEWO: 184.8 +GAREM2 FAM59B, FLJ00375, GAREML, KIAA2038 ENSG00000157833 GRB2 associated regulator of MAPK1 subtype 2 2 26173091-26189663 Predicted intracellular proteins Evidence at protein level HPA071575 Approved Cytosol Mixed Group enriched 6 cerebral cortex: 23.0;parathyroid gland: 17.8 smooth muscle: 3.4 Cell line enhanced HAP1: 17.3;U-2 OS: 14.6 +SPPL3 DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4 ENSG00000157837 Signal peptide peptidase like 3 12 120762510-120904371 Enzymes, Predicted membrane proteins Evidence at protein level HPA004194, HPA059958 Uncertain Supported Vesicles
Plasma membrane Liver cancer:1.29e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 84.1 Mixed +DPYSL5 CRAM, CRMP-5, CRMP5, Ulip6 ENSG00000157851 Dihydropyrimidinase like 5 2 26847747-26950351 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034544, HPA072387 Enhanced Approved Nucleoplasm
Cytosol Group enriched Group enriched 8 cerebral cortex: 31.3;testis: 10.0 adrenal gland: 2.5 Cell line enhanced AF22: 139.1;HAP1: 122.4;SCLC-21H: 196.8;SH-SY5Y: 105.0 +DRC1 C2orf39, CCDC164, CILD21, FLJ32660, MGC16372 ENSG00000157856 Dynein regulatory complex subunit 1 2 26401916-26456711 Disease related genes, Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 10 fallopian tube: 62.4;testis: 36.8 lung: 4.7 Not detected +RAB28 ENSG00000157869 RAB28, member RAS oncogene family 4 13361354-13484365 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044575 Approved Urothelial cancer:1.61e-4 (favourable) Expressed in all Expressed in all testis: 67.7 Expressed in all +FAM213B C1orf93, MGC26818 ENSG00000157870 Family with sequence similarity 213 member B 1 2586491-2591469 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006403 Approved Approved Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.28e-4 (favourable), Liver cancer:1.62e-4 (unfavourable) Expressed in all Mixed small intestine: 14.6 Mixed +TNFRSF14 ATAR, CD270, HVEA, HVEM, LIGHTR, TR2 ENSG00000157873 TNF receptor superfamily member 14 1 2555639-2565382 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA006404, CAB026150, CAB030007 Approved Approved Cytosol
Rods & Rings Urothelial cancer:7.79e-6 (favourable), Endometrial cancer:8.01e-6 (favourable), Breast cancer:4.39e-5 (favourable) Expressed in all Expressed in all duodenum: 45.5 Cell line enhanced CAPAN-2: 23.4;HDLM-2: 25.7;HHSteC: 25.4;SK-MEL-30: 41.0 +PANK4 FLJ10782 ENSG00000157881 Pantothenate kinase 4 1 2508533-2526628 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011723, HPA012036, HPA027961 Uncertain Approved Cytosol Renal cancer:1.57e-5 (favourable) Expressed in all Tissue enhanced appendix: 3.2 skin: 2.9 Mixed +CIB4 ENSG00000157884 Calcium and integrin binding family member 4 2 26581202-26641368 Predicted intracellular proteins Evidence at protein level HPA036130, HPA036131 Uncertain Tissue enhanced Group enriched 10 testis: 20.1;thyroid gland: 4.2 placenta: 1.1 Not detected +MEGF11 DKFZp434L121, KIAA1781 ENSG00000157890 Multiple EGF like domains 11 15 65895079-66253747 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA017982 Uncertain Tissue enhanced Group enriched 6 cerebral cortex: 13.0;fallopian tube: 12.3 testis: 1.9 Cell line enhanced AN3-CA: 3.1;HEK 293: 2.4;RPTEC TERT1: 7.0;SCLC-21H: 8.5 +C12orf43 FLJ12448 ENSG00000157895 Chromosome 12 open reading frame 43 12 121000486-121016502 Predicted intracellular proteins Evidence at protein level HPA046148, HPA061739 Uncertain Enhanced Nucleoli
Golgi apparatus Liver cancer:1.29e-6 (unfavourable), Lung cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 20.8 Expressed in all +PEX10 RNF69 ENSG00000157911 Peroxisomal biogenesis factor 10 1 2403964-2413797 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA049458, HPA049755 Approved Approved Nucleoplasm Renal cancer:4.16e-6 (favourable), Breast cancer:4.50e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 19.2 Expressed in all +RER1 ENSG00000157916 Retention in endoplasmic reticulum sorting receptor 1 1 2391775-2405444 Predicted membrane proteins, Transporters Evidence at protein level CAB037240, HPA051400 Supported Enhanced Golgi apparatus Renal cancer:8.23e-8 (unfavourable) Expressed in all Expressed in all testis: 186.8 Expressed in all +RADIL FLJ10324, KIAA1849, RASIP2 ENSG00000157927 Rap associating with DIL domain 7 4797055-4883719 Predicted intracellular proteins Evidence at protein level HPA051776 Approved Approved Nucleus
Nuclear membrane Mixed Tissue enhanced testis: 9.5 lung: 4.3 Cell line enhanced AN3-CA: 8.1;SCLC-21H: 12.4;SH-SY5Y: 24.2 +SKI ENSG00000157933 SKI proto-oncogene 1 2228695-2310119 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010449, HPA066567 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all endometrium: 36.2 Expressed in all +WIPI2 ATG18B, ATG21, CGI-50, DKFZP434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984 ENSG00000157954 WD repeat domain, phosphoinositide interacting 2 7 5190188-5233826 Predicted intracellular proteins Evidence at protein level HPA019852, HPA021488 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:2.05e-6 (favourable), Endometrial cancer:7.69e-5 (unfavourable), Pancreatic cancer:9.78e-4 (favourable) Expressed in all Expressed in all testis: 92.7 Expressed in all +LDLRAP1 ARH, ARH2, DKFZp586D0624, FHCB1, FHCB2, MGC34705 ENSG00000157978 Low density lipoprotein receptor adaptor protein 1 1 25543580-25568886 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB003705, HPA050358 Approved Approved Microtubules Expressed in all Expressed in all spleen: 50.9 Mixed +AGAP1 CENTG2, GGAP1, KIAA1099 ENSG00000157985 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 2 235494089-236131800 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051405 Uncertain Liver cancer:2.60e-5 (unfavourable), Renal cancer:6.52e-5 (favourable), Ovarian cancer:9.75e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.5 Cell line enhanced SCLC-21H: 93.8 +KRTCAP3 KCP3 ENSG00000157992 Keratinocyte associated protein 3 2 27442366-27446481 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047136, HPA060203 Enhanced Approved Nucleus
Cytosol Breast cancer:2.67e-5 (favourable) Expressed in all Mixed small intestine: 34.8 Cell line enhanced A-431: 53.9;CAPAN-2: 60.3;SCLC-21H: 37.2 +ANKRD61 ENSG00000157999 Ankyrin repeat domain 61 7 6031376-6036386 Predicted intracellular proteins Evidence at transcript level HPA029511 Uncertain Mixed Tissue enhanced testis: 11.0 bone marrow: 4.0 Cell line enhanced HeLa: 5.6 +PAFAH2 HSD-PLA2 ENSG00000158006 Platelet activating factor acetylhydrolase 2 1 25959767-25998157 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018157 Approved Renal cancer:0.00e+0 (favourable), Endometrial cancer:3.28e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 29.1 Expressed in all +EXTL1 EXTL, MGC70794 ENSG00000158008 Exostosin like glycosyltransferase 1 1 26019884-26036464 Enzymes, Predicted secreted proteins Evidence at protein level HPA037749 Approved Tissue enriched Tissue enhanced cerebral cortex: 11.2 skeletal muscle: 4.3 Cell line enriched 10 WM-115: 148.7 +SLC30A2 ZNT2 ENSG00000158014 Solute carrier family 30 member 2 1 26037252-26046133 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA017979 Approved Vesicles Renal cancer:2.86e-6 (favourable) Tissue enhanced Tissue enhanced kidney: 22.0;thyroid gland: 42.4 pancreas: 16.5 Group enriched 5 BEWO: 2.4;RPTEC TERT1: 4.3;WM-115: 3.5 +BRE BRCC4, BRCC45 ENSG00000158019 Brain and reproductive organ-expressed (TNFRSF1A modulator) 2 27889941-28338901 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA017926 Approved Supported Cytosol Liver cancer:6.33e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 189.5 Expressed in all +TRIM63 IRF, MURF-1, RNF28, SMRZ ENSG00000158022 Tripartite motif containing 63 1 26051304-26068436 Enzymes, Predicted intracellular proteins Evidence at protein level Tissue enriched Group enriched 16 heart muscle: 101.2;skeletal muscle: 139.3 esophagus: 7.6 Group enriched 35 ASC diff: 11.0;SK-MEL-30: 42.2 +WDR66 CaM-IP4, MGC33630 ENSG00000158023 WD repeat domain 66 12 121917862-122003927 Predicted intracellular proteins Evidence at protein level HPA039902, HPA040005 Supported Uncertain Plasma membrane
Cytosol Endometrial cancer:3.11e-4 (favourable) Mixed Tissue enhanced fallopian tube: 32.6;testis: 30.7 thyroid gland: 7.4 Cell line enhanced HBEC3-KT: 22.5;hTCEpi: 21.0;hTERT-HME1: 15.0 +MRPL17 MRP-L26, RPML26 ENSG00000158042 Mitochondrial ribosomal protein L17 11 6680782-6683401 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043666, HPA050552 Uncertain Uncertain Nucleoli
Golgi apparatus
Vesicles Renal cancer:3.15e-7 (unfavourable), Liver cancer:2.59e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 37.0 Expressed in all +DUSP2 PAC-1 ENSG00000158050 Dual specificity phosphatase 2 2 96143166-96145440 Enzymes, Predicted intracellular proteins Evidence at protein level HPA071920 Supported Nucleus
Nuclear membrane Renal cancer:4.97e-5 (unfavourable) Expressed in all Tissue enhanced bone marrow: 78.9;seminal vesicle: 86.2 lymph node: 50.7 Cell line enhanced RT4: 27.2;SCLC-21H: 34.8;U-698: 28.6 +GRHL3 SOM, TFCP2L4 ENSG00000158055 Grainyhead like transcription factor 3 1 24319322-24364482 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA059960 Enhanced Approved Nucleoplasm Tissue enhanced Group enriched 11 esophagus: 85.1;skin: 50.1;tonsil: 22.6;urinary bladder: 28.1 testis: 4.3 Cell line enhanced BEWO: 43.8;HaCaT: 32.1;MCF7: 43.8;RT4: 51.5 +UBXN11 SOC, SOCI, UBXD5 ENSG00000158062 UBX domain protein 11 1 26281328-26318363 Predicted intracellular proteins Evidence at protein level HPA028600, HPA031357 Approved Approved Nucleoli
Cytosol Liver cancer:5.90e-6 (unfavourable), Cervical cancer:2.54e-5 (favourable), Endometrial cancer:1.90e-4 (favourable), Head and neck cancer:4.90e-4 (favourable) Expressed in all Expressed in all fallopian tube: 50.2 Expressed in all +NLRP14 CLR11.2, GC-LRR, Nalp-iota, NALP14, NOD5, PAN8 ENSG00000158077 NLR family pyrin domain containing 14 11 7020446-7071308 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039477 Uncertain Uncertain Cytosol Not detected Tissue enhanced testis: 1.6 parathyroid gland: 0.6 Not detected +PTPDC1 FLJ37312, PTP9Q22 ENSG00000158079 Protein tyrosine phosphatase domain containing 1 9 94030794-94109856 Predicted intracellular proteins Evidence at protein level HPA016747, HPA026832 Uncertain Supported Nucleoplasm Expressed in all Mixed testis: 14.2 Mixed +GALNT14 FLJ12691, GalNac-T10, GalNac-T14 ENSG00000158089 Polypeptide N-acetylgalactosaminyltransferase 14 2 30910467-31155202 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030138 Approved Nucleus
Golgi apparatus Tissue enriched Tissue enhanced kidney: 40.3 parathyroid gland: 12.8 Cell line enhanced RPTEC TERT1: 29.5;RT4: 23.6;SCLC-21H: 25.2 +NCK1 NCK, NCKalpha ENSG00000158092 NCK adaptor protein 1 3 136862208-136949823 Predicted intracellular proteins Evidence at protein level CAB005063, HPA030766 Supported Enhanced Plasma membrane
Cytosol Pancreatic cancer:9.14e-5 (unfavourable), Renal cancer:1.08e-4 (unfavourable) Expressed in all Expressed in all lymph node: 48.8 Expressed in all +HPD 4-HPPD, 4HPPD, GLOD3, PPD ENSG00000158104 4-hydroxyphenylpyruvate dioxygenase 12 121839527-121863596 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038321, HPA038322 Enhanced Uncertain Nuclear speckles Tissue enriched Group enriched 86 kidney: 529.9;liver: 1293.2 seminal vesicle: 10.5 Cell line enriched 24 Hep G2: 349.1 +RHPN1 KIAA1929, ODF5, RHPN ENSG00000158106 Rhophilin Rho GTPase binding protein 1 8 143368887-143384220 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024288, HPA024671 Approved Approved Nucleoplasm Expressed in all Tissue enhanced cerebral cortex: 7.1 parathyroid gland: 4.8 Cell line enhanced MCF7: 21.9;MOLT-4: 21.1;T-47d: 42.5 +TPRG1L FAM79A, FLJ21811, RP11-46F15.3 ENSG00000158109 Tumor protein p63 regulated 1 like 1 3625002-3630127 Predicted intracellular proteins Evidence at protein level HPA063163, CAB079051 Supported Approved Vesicles
Cytosol Renal cancer:1.76e-9 (favourable) Expressed in all Expressed in all cerebral cortex: 102.1 Expressed in all +LRRC43 MGC35140 ENSG00000158113 Leucine rich repeat containing 43 12 122167738-122203471 Predicted intracellular proteins Evidence at transcript level HPA039425, HPA047606 Uncertain Approved Golgi apparatus
Vesicles Mixed Group enriched 5 fallopian tube: 30.3;testis: 8.5 parathyroid gland: 3.6 Cell line enhanced HUVEC TERT2: 2.2;SCLC-21H: 2.5 +AAED1 C9orf21 ENSG00000158122 AhpC/TSA antioxidant enzyme domain containing 1 9 96639577-96655303 Predicted intracellular proteins Evidence at protein level HPA021294 Approved Renal cancer:3.26e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 15.9 Mixed +XDH XO, XOR ENSG00000158125 Xanthine dehydrogenase 2 31334321-31414715 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062641, HPA069323 Supported Supported Nucleus Urothelial cancer:8.73e-6 (favourable) Mixed Tissue enhanced breast: 48.3;duodenum: 45.6;liver: 35.9;small intestine: 54.6 colon: 11.2 Cell line enhanced HBEC3-KT: 14.4;hTERT-HME1: 23.9 +XKR8 FLJ10307 ENSG00000158156 XK related 8 1 27959462-27968096 Predicted membrane proteins, Transporters Evidence at protein level HPA049984, HPA053529 Uncertain Approved Golgi apparatus Breast cancer:8.63e-4 (favourable) Expressed in all Expressed in all placenta: 13.7 Mixed +CNNM4 ACDP4, KIAA1592 ENSG00000158158 Cyclin and CBS domain divalent metal cation transport mediator 4 2 96760902-96811891 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA017732 Enhanced Uncertain Plasma membrane
Actin filaments Ovarian cancer:8.75e-4 (unfavourable), Endometrial cancer:9.14e-4 (unfavourable) Expressed in all Expressed in all rectum: 36.9 Expressed in all +EYA3 DKFZp686C132 ENSG00000158161 EYA transcriptional coactivator and phosphatase 3 1 27970344-28088696 Enzymes, Predicted intracellular proteins Evidence at protein level HPA052432, HPA062889 Uncertain Enhanced Nucleoplasm Renal cancer:3.15e-6 (favourable), Head and neck cancer:5.11e-4 (favourable) Expressed in all Expressed in all testis: 20.8 Expressed in all +DZIP1L DZIP2, FLJ32844 ENSG00000158163 DAZ interacting zinc finger protein 1 like 3 138061990-138115818 Predicted intracellular proteins Evidence at protein level HPA030404 Approved Approved Nucleoplasm
Microtubules
Cytokinetic bridge Mixed Mixed fallopian tube: 16.6 Mixed +TMSB15A TMSL8, TMSNB ENSG00000158164 Thymosin beta 15a X 102513676-102516784 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enhanced prostate: 22.5 thyroid gland: 8.5 Cell line enhanced AF22: 507.9;NTERA-2: 133.4;RH-30: 226.1;SH-SY5Y: 141.1 +FANCC FA3, FAC, FACC ENSG00000158169 Fanconi anemia complementation group C 9 95099054-95426796 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017793, HPA030771 Approved Supported Nucleoplasm Renal cancer:6.03e-6 (favourable) Expressed in all Mixed testis: 17.6 Expressed in all +MRAS M-RAs, R-RAS3, RRAS3 ENSG00000158186 Muscle RAS oncogene homolog 3 138347648-138405534 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA042728 Approved Endometrial cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 114.0 Cell line enhanced EFO-21: 110.3 +WASF2 SCAR2, WAVE2 ENSG00000158195 WAS protein family member 2 1 27404226-27490158 Predicted intracellular proteins Evidence at protein level CAB022632, HPA045288 Enhanced Approved Plasma membrane
Cytosol Liver cancer:5.29e-8 (unfavourable), Ovarian cancer:8.48e-4 (unfavourable) Expressed in all Expressed in all esophagus: 88.1 Expressed in all +ABHD3 LABH3 ENSG00000158201 Abhydrolase domain containing 3 18 21650897-21704805 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010729 Approved Approved Nucleus
Vesicles
Plasma membrane Melanoma:8.52e-4 (unfavourable) Expressed in all Expressed in all rectum: 71.5 Cell line enhanced REH: 188.5;RPMI-8226: 159.6 +ESYT3 CHR3SYT, FAM62C ENSG00000158220 Extended synaptotagmin 3 3 138434586-138481686 Predicted membrane proteins, Transporters Evidence at protein level HPA039200 Approved Lung cancer:8.30e-4 (favourable) Tissue enhanced Tissue enhanced lung: 8.4;skin: 7.5;thyroid gland: 8.5 endometrium: 3.7 Cell line enhanced NTERA-2: 4.1;SCLC-21H: 5.2;SiHa: 1.9 +FAIM FAIM1, FLJ10582 ENSG00000158234 Fas apoptotic inhibitory molecule 3 138608606-138633376 Predicted intracellular proteins Evidence at protein level HPA042440, HPA052209 Approved Approved Plasma membrane
Cytosol Liver cancer:3.96e-5 (unfavourable), Renal cancer:6.63e-4 (favourable) Expressed in all Expressed in all fallopian tube: 61.0 Mixed +FAM46B MGC16491 ENSG00000158246 Family with sequence similarity 46 member B 1 27005020-27012836 Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced esophagus: 59.9;skin: 39.4 seminal vesicle: 22.1 Cell line enhanced hTCEpi: 45.0;NTERA-2: 32.9 +CLSTN2 CDHR13, CS2, CSTN2, FLJ39113 ENSG00000158258 Calsyntenin 2 3 139935185-140577397 Predicted membrane proteins Evidence at protein level HPA031342 Approved Approved Nucleoplasm
Nuclear membrane
Cell Junctions Tissue enriched Tissue enhanced cerebral cortex: 34.6;ovary: 81.6 adipose tissue: 18.8 Cell line enhanced AF22: 5.2;SCLC-21H: 17.0;THP-1: 6.3 +COLEC12 CL-P1, SCARA4, SRCL ENSG00000158270 Collectin subfamily member 12 18 316740-500722 Predicted membrane proteins Evidence at protein level HPA047917, HPA071056 Enhanced Approved Golgi apparatus
Vesicles
Cell Junctions Thyroid cancer:8.10e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 28.2 lung: 16.7 Cell line enhanced ASC TERT1: 16.8;BJ: 10.3;HSkMC: 14.5;U-2197: 29.2 +RNF207 C1orf188, FLJ32096, FLJ46380 ENSG00000158286 Ring finger protein 207 1 6205475-6221299 Predicted intracellular proteins Evidence at protein level HPA028378, HPA042535 Uncertain Approved Cytosol Renal cancer:1.92e-4 (unfavourable) Mixed Tissue enhanced heart muscle: 11.1 seminal vesicle: 5.2 Cell line enhanced CAPAN-2: 14.3 +CUL4B ENSG00000158290 Cullin 4B X 120524609-120575794 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003046, HPA011880, CAB017786, HPA058979 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all testis: 68.3 Expressed in all +GPR153 PGR1 ENSG00000158292 G protein-coupled receptor 153 1 6247346-6260975 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA007159 Approved Endometrial cancer:3.07e-4 (unfavourable), Lung cancer:3.75e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 17.4 Cell line enhanced PC-3: 65.6;RH-30: 32.1;SCLC-21H: 39.5 +SLC13A3 NADC3, SDCT2 ENSG00000158296 Solute carrier family 13 member 3 20 46557823-46684467 Predicted membrane proteins, Transporters Evidence at protein level HPA014333, HPA014353, HPA014736 Enhanced Supported Plasma membrane Mixed Tissue enriched 7 kidney: 431.7 placenta: 60.9 Cell line enhanced EFO-21: 17.7;Hep G2: 38.2 +GPRASP2 FLJ37327, GASP2 ENSG00000158301 G protein-coupled receptor associated sorting protein 2 X 102712176-102717733 Predicted intracellular proteins Evidence at protein level HPA017438 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:4.60e-6 (favourable), Urothelial cancer:6.63e-5 (unfavourable), Pancreatic cancer:5.71e-4 (favourable) Expressed in all Mixed cerebral cortex: 41.6 Mixed +RHBDL2 FLJ20435 ENSG00000158315 Rhomboid like 2 1 38885807-38941799 Enzymes, Predicted membrane proteins Evidence at protein level HPA043807 Approved Mixed Mixed skin: 22.1 Cell line enhanced CAPAN-2: 40.9;HaCaT: 21.4;RT4: 37.8 +AUTS2 FBRSL2, KIAA0442 ENSG00000158321 AUTS2, activator of transcription and developmental regulator 7 69598919-70793068 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000390 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all skin: 21.7 Cell line enhanced NTERA-2: 68.0;SCLC-21H: 136.5 +SHROOM4 KIAA1202 ENSG00000158352 Shroom family member 4 X 50591647-50814302 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA010565 Uncertain Renal cancer:4.66e-4 (unfavourable), Endometrial cancer:8.37e-4 (unfavourable) Mixed Tissue enhanced lung: 19.2 placenta: 13.1 Cell line enhanced EFO-21: 6.5;HUVEC TERT2: 22.2;TIME: 8.3 +HIST1H2BD H2B/b, H2BFB ENSG00000158373 Histone cluster 1 H2B family member d 6 26158146-26171349 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671, CAB062336 Supported Approved Nucleoplasm
Cytosol Colorectal cancer:3.84e-4 (unfavourable) Expressed in all Expressed in all prostate: 90.2 Expressed in all +CDC25C CDC25, PPP1R60 ENSG00000158402 Cell division cycle 25C 5 138285265-138338355 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB003800, HPA066991 Approved Supported Nuclear speckles Liver cancer:3.03e-6 (unfavourable), Colorectal cancer:2.49e-4 (favourable), Lung cancer:4.38e-4 (unfavourable) Mixed Tissue enriched 7 testis: 31.8 rectum: 4.4 Mixed +HIST1H4H H4/h, H4FH ENSG00000158406 Histone cluster 1 H4 family member h 6 26277609-26285638 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Renal cancer:6.18e-6 (unfavourable), Liver cancer:6.84e-4 (unfavourable) Expressed in all Tissue enhanced breast: 9.9 prostate: 6.3 Cell line enhanced U-266/84: 49.1 +MITD1 LOC129531 ENSG00000158411 Microtubule interacting and trafficking domain containing 1 2 99161427-99181058 Predicted intracellular proteins Evidence at protein level HPA036162, HPA036163 Approved Enhanced Vesicles Renal cancer:1.32e-11 (unfavourable), Urothelial cancer:5.46e-8 (favourable), Liver cancer:1.47e-6 (unfavourable), Breast cancer:5.96e-4 (favourable) Expressed in all Expressed in all lymph node: 42.2 Expressed in all +EIF5B DKFZp434I036, FLJ10524, IF2, KIAA0741 ENSG00000158417 Eukaryotic translation initiation factor 5B 2 99337353-99401326 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034648, HPA040095 Approved Approved Plasma membrane
Cytosol Liver cancer:7.15e-10 (unfavourable), Renal cancer:1.42e-6 (unfavourable), Ovarian cancer:8.99e-4 (favourable) Expressed in all Expressed in all testis: 67.5 Expressed in all +RIBC1 FLJ32783 ENSG00000158423 RIB43A domain with coiled-coils 1 X 53422690-53431120 Predicted intracellular proteins Evidence at protein level HPA001150, HPA021613 Uncertain Approved Nuclear bodies Cervical cancer:1.90e-5 (favourable), Endometrial cancer:9.66e-4 (favourable) Mixed Group enriched 7 fallopian tube: 45.0;testis: 41.7 thyroid gland: 6.1 Cell line enhanced T-47d: 7.4 +TMSB15B MGC39900 ENSG00000158427 Thymosin beta 15B X 103918896-103966712 Predicted intracellular proteins Evidence at protein level HPA064607 Uncertain Not detected Mixed endometrium: 18.6 Cell line enhanced AF22: 73.0;REH: 52.5 +CATIP C2orf62, MGC50811 ENSG00000158428 Ciliogenesis associated TTC17 interacting protein 2 218356856-218368099 Predicted intracellular proteins Evidence at protein level HPA044818 Supported Mixed Tissue enhanced fallopian tube: 31.9 testis: 7.3 Cell line enriched 14 BEWO: 3.7 +CNOT11 C2orf29, C40 ENSG00000158435 CCR4-NOT transcription complex subunit 11 2 101252802-101270316 Predicted intracellular proteins Evidence at protein level HPA069823 Supported Nucleoplasm Renal cancer:8.33e-6 (unfavourable), Liver cancer:1.05e-4 (unfavourable) Expressed in all Expressed in all testis: 52.0 Expressed in all +KCNB1 Kv2.1 ENSG00000158445 Potassium voltage-gated channel subfamily B member 1 20 49293394-49484297 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB001979, HPA042434 Enhanced Mixed Tissue enhanced adipose tissue: 10.9;cerebral cortex: 21.6 fallopian tube,smooth muscle: 7.4 Cell line enhanced CACO-2: 1.8;U-2 OS: 1.8 +TSPAN33 MGC50844, Penumbra ENSG00000158457 Tetraspanin 33 7 129144892-129169697 Predicted membrane proteins, Transporters Evidence at protein level HPA020357 Approved Approved Microtubules Renal cancer:8.74e-5 (favourable), Pancreatic cancer:8.88e-4 (favourable) Expressed in all Expressed in all kidney: 127.3 Cell line enhanced AN3-CA: 48.8;HEL: 76.0;U-266/70: 73.4 +NRG2 Don-1, HRG2, NTAK ENSG00000158458 Neuregulin 2 5 139846779-140043299 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA038935, HPA047973 Uncertain Supported Nucleus
Nucleoli Mixed Tissue enhanced parathyroid gland: 13.3 ovary: 10.2 Cell line enhanced AN3-CA: 7.0;PC-3: 12.4;SCLC-21H: 5.8 +AHCYL2 KIAA0828 ENSG00000158467 Adenosylhomocysteinase like 2 7 129225023-129430211 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053128 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.08e-7 (favourable), Head and neck cancer:4.17e-4 (favourable) Expressed in all Expressed in all rectum: 194.5 Cell line enriched 9 HDLM-2: 218.4 +B4GALT5 beta4GalT-V ENSG00000158470 Beta-1,4-galactosyltransferase 5 20 49632945-49713878 Predicted secreted proteins Evidence at protein level Pancreatic cancer:1.87e-5 (unfavourable), Liver cancer:2.69e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 59.8 Expressed in all +CD1D ENSG00000158473 CD1d molecule 1 158179947-158184896 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level CAB016107, HPA072662 Uncertain Supported Endoplasmic reticulum Renal cancer:2.12e-5 (unfavourable) Mixed Mixed spleen: 20.6 Cell line enhanced HBEC3-KT: 8.3;HHSteC: 14.4;MOLT-4: 19.6;THP-1: 9.9 +CD1A CD1 ENSG00000158477 CD1a molecule 1 158254137-158258269 CD markers, Predicted membrane proteins Evidence at protein level CAB000009, HPA010734 Enhanced Cervical cancer:6.37e-4 (favourable) Mixed Group enriched 6 esophagus: 9.5;skin: 27.0 lymph node,tonsil: 2.9 Cell line enriched 122 MOLT-4: 48.8 +SPATA2 KIAA0757, PD1, PPP1R145, tamo ENSG00000158480 Spermatogenesis associated 2 20 49903391-49915508 Predicted intracellular proteins Evidence at protein level HPA048581, HPA052224 Uncertain Approved Nucleus
Nucleoli fibrillar center Endometrial cancer:1.87e-4 (unfavourable), Thyroid cancer:4.53e-4 (unfavourable), Melanoma:9.08e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 22.4 Expressed in all +CD1C CD1 ENSG00000158481 CD1c molecule 1 158289786-158293630 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Cervical cancer:1.79e-5 (favourable) Mixed Tissue enhanced spleen: 40.6;tonsil: 45.1 lymph node: 39.8 Cell line enriched 16 MOLT-4: 46.0 +FAM86C1 FAM86C, FLJ10661, FLJ27199 ENSG00000158483 Family with sequence similarity 86 member C1 11 71787510-71801236 Predicted intracellular proteins Evidence at protein level Liver cancer:5.79e-5 (unfavourable) Expressed in all Mixed thyroid gland: 9.8 Expressed in all +CD1B CD1 ENSG00000158485 CD1b molecule 1 158327951-158331531 CD markers, Predicted membrane proteins Evidence at protein level HPA021824 Approved Mixed Tissue enhanced rectum: 3.1;skin: 3.9 lymph node: 2.7 Cell line enriched 1556 MOLT-4: 465.4 +DNAH3 DKFZp434N074, DLP3, Dnahc3b, Hsadhc3 ENSG00000158486 Dynein axonemal heavy chain 3 16 20933111-21159441 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062493 Approved Nuclear membrane
Intermediate filaments Mixed Group enriched 5 fallopian tube: 8.1;testis: 6.0 lung: 1.3 Not detected +CD1E ENSG00000158488 CD1e molecule 1 158353696-158357553 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA057769 Uncertain Mixed Tissue enhanced skin: 18.3 tonsil: 10.4 Cell line enriched 980 MOLT-4: 1075.1 +HMHB1 HB-1, HB-1Y ENSG00000158497 Histocompatibility minor HB-1 5 143812161-143820719 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced lymph node: 1.3;testis: 2.4 bone marrow: 0.6 Cell line enhanced Karpas-707: 2.3;REH: 4.1 +CPA2 ENSG00000158516 Carboxypeptidase A2 7 130266827-130289798 Enzymes, Predicted secreted proteins Evidence at protein level HPA020342, HPA021317 Enhanced Tissue enriched Tissue enriched 104 pancreas: 9283.9 stomach: 89.6 Cell line enhanced AN3-CA: 2.0;CACO-2: 3.0;RH-30: 2.8;SCLC-21H: 1.9 +NCF1 NCF1A, NOXO2, p47phox, SH3PXD1A ENSG00000158517 Neutrophil cytosolic factor 1 7 74773962-74789315 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004524, HPA047836, HPA052095 Enhanced Mixed Tissue enhanced lymph node: 71.2;spleen: 74.1 bone marrow: 60.9 Group enriched 6 Daudi: 72.6;HMC-1: 122.5 +CPA5 ENSG00000158525 Carboxypeptidase A5 7 130344816-130368730 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020322 Approved Nucleus Not detected Tissue enriched 18 testis: 47.4 spleen: 2.6 Cell line enhanced RH-30: 7.1;RT4: 2.7;U-266/84: 4.1 +TSR2 DT1P1A10, RP1-112K5.2, WGG1 ENSG00000158526 TSR2, ribosome maturation factor X 54440401-54445487 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030514 Approved Approved Nucleus
Nucleoli
Cell Junctions
Cytosol Renal cancer:1.21e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 88.4 Expressed in all +PPP1R9A FLJ20068, KIAA1222, Neurabin-I ENSG00000158528 Protein phosphatase 1 regulatory subunit 9A 7 94907202-95296415 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027726, HPA075591 Uncertain Approved Plasma membrane Renal cancer:8.63e-6 (favourable), Ovarian cancer:7.17e-4 (favourable) Mixed Mixed cerebral cortex: 20.6 Mixed +ZC3H18 NHN1 ENSG00000158545 Zinc finger CCCH-type containing 18 16 88570381-88631966 Predicted intracellular proteins Evidence at protein level HPA040847, HPA041327 Enhanced Enhanced Nuclear speckles Renal cancer:3.68e-4 (favourable), Liver cancer:4.06e-4 (unfavourable) Expressed in all Expressed in all testis: 30.8 Expressed in all +ZFAND2B AIRAPL ENSG00000158552 Zinc finger AN1-type containing 2B 2 219195237-219209651 Predicted intracellular proteins Evidence at protein level HPA035159, HPA035160 Uncertain Approved Nucleus
Nucleoli
Cytosol Pancreatic cancer:9.38e-4 (favourable) Expressed in all Expressed in all thyroid gland: 68.0 Expressed in all +POM121L2 POM121-L ENSG00000158553 POM121 transmembrane nucleoporin like 2 6 27285903-27312170 Predicted intracellular proteins Evidence at transcript level HPA046150 Uncertain Not detected Tissue enriched 152 testis: 15.1 all non-specific tissues: 0.0 Not detected +GDPD5 GDE2, PP1665 ENSG00000158555 Glycerophosphodiester phosphodiesterase domain containing 5 11 75434640-75525903 Predicted membrane proteins Evidence at protein level HPA065257, HPA066762, HPA069281 Uncertain Approved Golgi apparatus Renal cancer:6.59e-9 (unfavourable), Endometrial cancer:1.29e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 67.0 testis: 31.2 Cell line enhanced HDLM-2: 62.5 +DYNC1I1 DNCI1, DNCIC1 ENSG00000158560 Dynein cytoplasmic 1 intermediate chain 1 7 95772506-96110322 Predicted intracellular proteins Evidence at protein level HPA061689 Enhanced Endometrial cancer:3.79e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 83.9 adrenal gland: 16.8 Cell line enhanced EFO-21: 13.2;SH-SY5Y: 11.0;WM-115: 9.0 +PFKFB1 PFRX ENSG00000158571 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 X 54932961-54998534 Enzymes, Predicted intracellular proteins Evidence at protein level Tissue enriched Group enriched 8 adipose tissue: 30.1;liver: 18.7;skeletal muscle: 39.3 breast: 3.8 Cell line enhanced ASC diff: 5.9;Hep G2: 2.4 +ALAS2 ASB ENSG00000158578 5'-aminolevulinate synthase 2 X 55009055-55031064 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001638 Approved Mixed Tissue enriched 7 bone marrow: 335.6 placenta: 51.0 Group enriched 173 HEL: 42.0;K-562: 61.5 +TMED4 HNLF, p24a3, p24alpha3 ENSG00000158604 Transmembrane p24 trafficking protein 4 7 44577894-44582287 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014650 Approved Renal cancer:1.37e-4 (favourable), Endometrial cancer:7.37e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 190.7 Expressed in all +PPP1R15B FLJ14744 ENSG00000158615 Protein phosphatase 1 regulatory subunit 15B 1 204403387-204411791 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA061088 Approved Golgi apparatus Renal cancer:8.74e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 81.6 Expressed in all +COPG2 2-COP ENSG00000158623 Coatomer protein complex subunit gamma 2 7 130506238-130668748 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045712 Approved Expressed in all Expressed in all ovary: 48.2 Expressed in all +EMSY C11orf30 ENSG00000158636 EMSY, BRCA2 interacting transcriptional repressor 11 76444923-76553025 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012234, HPA050777 Supported Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 20.4 Expressed in all +PAGE5 CT16.1, CT16.2, PAGE-5 ENSG00000158639 PAGE family member 5 X 55220355-55224108 Predicted intracellular proteins Evidence at protein level HPA052619, HPA055869 Supported Uncertain Mitochondria Group enriched Tissue enriched 74 testis: 41.0 fallopian tube,liver: 0.5 Group enriched 160 Karpas-707: 324.6;U-266/84: 709.6 +GPAT4 AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7 ENSG00000158669 Glycerol-3-phosphate acyltransferase 4 8 41577187-41625001 Enzymes, Predicted membrane proteins Evidence at protein level HPA016471 Approved Ovarian cancer:2.20e-4 (unfavourable), Prostate cancer:4.15e-4 (favourable), Urothelial cancer:5.65e-4 (favourable), Endometrial cancer:9.37e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 80.3 Expressed in all +PKD1L1 PRO19563 ENSG00000158683 Polycystin 1 like 1, transient receptor potential channel interacting 7 47774652-47948491 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA020422, HPA022424 Uncertain Tissue enhanced Tissue enhanced testis: 2.4 adipose tissue: 1.8 Group enriched 8 T-47d: 5.0;U-266/70: 10.5;U-266/84: 3.7 +ZSCAN12 dJ29K1.2, KIAA0426, ZFP96, ZNF29K1, ZNF305, ZNF96 ENSG00000158691 Zinc finger and SCAN domain containing 12 6 28378955-28399734 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006637 Approved Approved Microtubules
Cytosol Expressed in all Mixed thyroid gland: 8.7 Mixed +TAGLN2 HA1756, KIAA0120 ENSG00000158710 Transgelin 2 1 159918107-159925732 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001925 Approved Approved Actin filaments
Cytosol Renal cancer:1.92e-10 (unfavourable), Breast cancer:2.06e-5 (unfavourable), Liver cancer:7.07e-5 (unfavourable) Expressed in all Expressed in all lung: 902.5 Expressed in all +ELK4 SAP1 ENSG00000158711 ELK4, ETS transcription factor 1 205597556-205631962 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028863 Uncertain Supported Nucleoplasm Renal cancer:2.94e-6 (unfavourable), Head and neck cancer:4.65e-4 (favourable) Expressed in all Expressed in all prostate: 42.8 Expressed in all +SLAMF8 BLAME, CD353, SBBI42 ENSG00000158714 SLAM family member 8 1 159826750-159837249 CD markers, Predicted membrane proteins Evidence at protein level HPA067601 Enhanced Renal cancer:5.42e-5 (unfavourable) Expressed in all Tissue enhanced appendix: 39.3 lymph node: 36.1 Cell line enhanced ASC TERT1: 1.1;HL-60: 1.0;U-138 MG: 2.0;U-87 MG: 1.3 +SLC45A3 IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein ENSG00000158715 Solute carrier family 45 member 3 1 205657851-205680459 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level HPA019073, HPA019075 Enhanced Approved Nucleoplasm
Vesicles Endometrial cancer:4.04e-5 (unfavourable), Urothelial cancer:7.33e-5 (favourable) Tissue enriched Tissue enriched 30 prostate: 505.2 stomach: 16.5 Cell line enriched 28 HMC-1: 749.2 +DUSP23 DUSP25, FLJ20442 ENSG00000158716 Dual specificity phosphatase 23 1 159780932-159782543 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028211, HPA045792 Approved Supported Nucleoplasm Renal cancer:2.59e-5 (unfavourable), Liver cancer:3.06e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 40.4 Mixed +RNF166 MGC14381, MGC2647 ENSG00000158717 Ring finger protein 166 16 88696495-88706421 Predicted intracellular proteins Evidence at protein level HPA042970 Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:9.45e-6 (unfavourable), Pancreatic cancer:1.04e-4 (favourable) Expressed in all Expressed in all bone marrow: 57.1 Expressed in all +NBL1 D1S1733E, DAN, DAND1, NB, NO3 ENSG00000158747 Neuroblastoma 1, DAN family BMP antagonist 1 19640554-19658456 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007394, CAB026132 Uncertain Expressed in all Expressed in all ovary: 552.0 Cell line enhanced SK-MEL-30: 357.2 +HTR6 5-HT6, 5-HT6R ENSG00000158748 5-hydroxytryptamine receptor 6 1 19665287-19679562 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Tissue enhanced Not detected cerebral cortex: 0.8 Cell line enhanced SH-SY5Y: 2.1 +ITLN2 HL-2 ENSG00000158764 Intelectin 2 1 160945025-160954799 Predicted secreted proteins Evidence at protein level HPA006683, HPA067326 Enhanced Tissue enhanced Group enriched 19 duodenum: 244.7;small intestine: 454.0 lung: 18.2 Cell line enhanced HEL: 10.8;HMC-1: 3.0;SK-MEL-30: 3.0 +F11R CD321, JAM-1, JAM-A, JAM1, JAMA, JCAM, PAM-1 ENSG00000158769 F11 receptor 1 160995211-161021348 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB004671, HPA043616, HPA061700 Enhanced Supported Cell Junctions
Microtubules Expressed in all Expressed in all lung: 95.0 Cell line enhanced HaCaT: 179.6 +USF1 bHLHb11, MLTFI, UEF ENSG00000158773 Upstream transcription factor 1 1 161039251-161045977 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB001480, HPA036233, HPA036535 Supported Enhanced Nucleoplasm Renal cancer:6.01e-12 (unfavourable), Urothelial cancer:1.95e-5 (favourable), Head and neck cancer:8.70e-4 (favourable) Expressed in all Expressed in all spleen: 34.8 Expressed in all +PLA2G2F ENSG00000158786 Phospholipase A2 group IIF 1 20139326-20150386 Enzymes, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Urothelial cancer:3.86e-4 (favourable) Tissue enriched Group enriched 11 skin: 11.3;tonsil: 7.2;urinary bladder: 3.9 gallbladder: 0.6 Cell line enriched 57 RT4: 110.7 +SPATA2L C16orf76, MGC26885, tamo ENSG00000158792 Spermatogenesis associated 2 like 16 89696343-89701705 Predicted intracellular proteins Evidence at protein level HPA041182, HPA042453 Uncertain Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all Mixed cerebral cortex: 9.1 Cell line enhanced MCF7: 25.9 +NIT1 ENSG00000158793 Nitrilase 1 1 161118086-161125445 Predicted intracellular proteins Evidence at protein level HPA006657 Approved Renal cancer:4.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.9 Expressed in all +DEDD CASP8IP1, DEDD1, DEFT, FLDED1, KE05 ENSG00000158796 Death effector domain containing 1 161120974-161132688 Predicted intracellular proteins Evidence at protein level HPA030681, HPA073628 Approved Approved Nucleoplasm Renal cancer:4.98e-7 (unfavourable), Liver cancer:8.48e-4 (unfavourable) Expressed in all Expressed in all testis: 47.2 Expressed in all +ZNF276 CENP-Z, CENPZ, MGC45417, ZADT, ZFP276, ZNF477 ENSG00000158805 Zinc finger protein 276 16 89720400-89740903 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021309, HPA022255 Uncertain Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Renal cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all spleen: 22.9 Expressed in all +NPM2 ENSG00000158806 Nucleophosmin/nucleoplasmin 2 8 22024125-22036897 Predicted intracellular proteins Evidence at protein level HPA041070 Enhanced Approved Nucleus
Nucleoli Renal cancer:3.18e-6 (favourable), Pancreatic cancer:9.02e-4 (favourable) Tissue enhanced Tissue enhanced parathyroid gland: 69.7;thyroid gland: 42.7 cerebral cortex: 31.8 Cell line enhanced HaCaT: 15.6;HEL: 13.0;Hep G2: 21.9 +EDA ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED ENSG00000158813 Ectodysplasin A X 69616067-70039469 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA037972, HPA037973 Supported Vesicles
Lipid droplets Renal cancer:1.04e-9 (favourable) Mixed Tissue enhanced parathyroid gland: 19.4 thyroid gland: 10.0 Cell line enhanced EFO-21: 5.0;Hep G2: 12.2 +FGF17 FGF-13 ENSG00000158815 Fibroblast growth factor 17 8 22042398-22048809 Cancer-related genes, Disease related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA052600 Approved Tissue enhanced Mixed cerebral cortex: 1.8 Not detected +VWA5B1 FLJ32784 ENSG00000158816 Von Willebrand factor A domain containing 5B1 1 20290919-20354894 Predicted intracellular proteins Evidence at protein level HPA027496, HPA028405, HPA064829 Enhanced Approved Plasma membrane
Mitochondria
Cytosol Mixed Tissue enhanced testis: 5.0 epididymis: 1.6 Cell line enriched 10 SCLC-21H: 1.4 +CDA CDD ENSG00000158825 Cytidine deaminase 1 20588948-20618908 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064202 Enhanced Approved Nucleoplasm Pancreatic cancer:8.56e-5 (unfavourable), Cervical cancer:5.05e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 104.6;esophagus: 56.7 liver: 33.3 Cell line enhanced A-431: 142.3;CAPAN-2: 92.8;HeLa: 100.6;SiHa: 200.2 +PINK1 PARK6 ENSG00000158828 PTEN induced putative kinase 1 1 20633455-20651511 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001931, CAB026191 Uncertain Renal cancer:1.11e-16 (favourable) Expressed in all Expressed in all cerebral cortex: 145.5 Expressed in all +B4GALT3 beta4Gal-T3 ENSG00000158850 Beta-1,4-galactosyltransferase 3 1 161171310-161177968 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010793 Approved Supported Golgi apparatus Renal cancer:7.12e-7 (unfavourable), Liver cancer:5.87e-5 (unfavourable) Expressed in all Expressed in all placenta: 31.1 Expressed in all +DMTN DMT, EPB49 ENSG00000158856 Dematin actin binding protein 8 22048995-22082527 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024290 Uncertain Renal cancer:3.85e-9 (favourable), Glioma:4.61e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 221.5 Cell line enhanced HEL: 202.5 +ADAMTS4 ADAMTS-2, ADMP-1, KIAA0688 ENSG00000158859 ADAM metallopeptidase with thrombospondin type 1 motif 4 1 161184308-161199056 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025876, HPA051296, HPA068374 Uncertain Approved Nuclear speckles Renal cancer:7.27e-7 (unfavourable), Lung cancer:5.00e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 62.8 appendix: 22.9 Cell line enhanced hTEC/SVTERT24-B: 11.8;HUVEC TERT2: 12.0;SH-SY5Y: 8.4;TIME: 9.9;U-251 MG: 9.0 +FAM160B2 FLJ21801, RAI16 ENSG00000158863 Family with sequence similarity 160 member B2 8 22089159-22104898 Predicted intracellular proteins Evidence at protein level HPA025040 Approved Approved Nucleoplasm
Cytosol Head and neck cancer:4.56e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 17.7 Mixed +NDUFS2 CI-49 ENSG00000158864 NADH:ubiquinone oxidoreductase core subunit S2 1 161197104-161214395 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA055140, HPA061953 Enhanced Enhanced Nucleoplasm
Mitochondria Renal cancer:2.32e-4 (favourable) Expressed in all Expressed in all heart muscle: 124.0 Expressed in all +SLC5A11 KST1, SGLT6, SMIT2 ENSG00000158865 Solute carrier family 5 member 11 16 24845841-24911628 Predicted membrane proteins Evidence at protein level HPA035331 Uncertain Approved Nucleus
Cytosol Mixed Group enriched 5 cerebral cortex: 10.5;duodenum: 6.6;kidney: 6.1;small intestine: 15.2 breast: 1.7 Cell line enhanced BEWO: 1.7;Hep G2: 11.2;Karpas-707: 3.2 +FCER1G ENSG00000158869 Fc fragment of IgE receptor Ig 1 161215234-161220699 FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB022108, HPA026872 Supported Renal cancer:1.83e-6 (unfavourable) Expressed in all Expressed in all spleen: 462.9 Group enriched 5 HEL: 69.1;HMC-1: 265.2;THP-1: 185.7;U-266/84: 61.5;U-937: 67.6 +APOA2 ENSG00000158874 Apolipoprotein A2 1 161222292-161223631 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025885 Supported Tissue enriched Tissue enriched 1068 liver: 18325.0 bone marrow: 17.1 Cell line enriched 8 Hep G2: 11388.0 +TOMM40L FLJ12770, TOMM40B ENSG00000158882 Translocase of outer mitochondrial membrane 40 like 1 161225939-161230744 Predicted intracellular proteins Evidence at protein level HPA051304 Approved Liver cancer:1.36e-4 (unfavourable), Endometrial cancer:1.44e-4 (unfavourable), Renal cancer:7.80e-4 (favourable) Expressed in all Mixed parathyroid gland: 20.3 Expressed in all +MPZ CMT1, CMT1B, CMT2I, CMT2J, HMSNIB ENSG00000158887 Myelin protein zero 1 161304735-161309972 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA068925 Supported Tissue enriched Mixed seminal vesicle: 16.7 Cell line enriched 8 WM-115: 201.9 +WFDC8 C20orf170, dJ461P17.1, WAP8 ENSG00000158901 WAP four-disulfide core domain 8 20 45551153-45579326 Predicted secreted proteins Evidence at protein level HPA042710, HPA071119 Enhanced Not detected Tissue enriched 436 epididymis: 487.6 seminal vesicle: 1.1 Cell line enriched 6 U-87 MG: 2.6 +CCAR2 DBC-1, DBC1, KIAA1967, NET35 ENSG00000158941 Cell cycle and apoptosis regulator 2 8 22604632-22621514 Predicted intracellular proteins Evidence at protein level HPA019907, HPA019943, CAB072827, CAB072828 Enhanced Enhanced Nucleoplasm
Nuclear bodies Renal cancer:5.60e-4 (favourable) Expressed in all Expressed in all testis: 135.8 Expressed in all +WNT9B WNT14B, WNT15 ENSG00000158955 Wnt family member 9B 17 46833201-46886730 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA058361, HPA059572 Approved Not detected Tissue enhanced parathyroid gland: 3.1;seminal vesicle: 9.4 skin: 1.4 Not detected +CACHD1 KIAA1573, VWCD1 ENSG00000158966 Cache domain containing 1 1 64470792-64693058 Predicted membrane proteins Evidence at protein level HPA017202 Uncertain Uncertain Nucleus
Nucleoli Expressed in all Mixed ovary: 28.1 Cell line enhanced AF22: 40.8;NTERA-2: 56.8 +CDC42SE2 FLJ21967, SPEC2 ENSG00000158985 CDC42 small effector 2 5 131245493-131398447 Predicted intracellular proteins Evidence at protein level HPA038624 Enhanced Colorectal cancer:4.50e-5 (favourable), Urothelial cancer:7.50e-4 (favourable) Expressed in all Expressed in all lymph node: 92.9 Expressed in all +RAPGEF6 PDZ-GEF2, PDZGEF2, RA-GEF-2 ENSG00000158987 Rap guanine nucleotide exchange factor 6 5 131423921-131635236 Predicted intracellular proteins Evidence at protein level HPA037982, HPA037983 Approved Approved Centrosome
Cytosol Renal cancer:3.87e-4 (unfavourable) Expressed in all Mixed lymph node: 21.9 Expressed in all +EPB41 4.1R, EL1 ENSG00000159023 Erythrocyte membrane protein band 4.1 1 28887091-29120046 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA028076, HPA028412, HPA028414 Supported Supported Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.75e-6 (unfavourable), Endometrial cancer:4.58e-4 (unfavourable), Head and neck cancer:5.87e-4 (favourable) Expressed in all Expressed in all lymph node: 50.6 Mixed +MIS18A B28, C21orf45, C21orf46, FASP1, hMis18alpha ENSG00000159055 MIS18 kinetochore protein A 21 32268219-32279069 Predicted intracellular proteins Evidence at protein level HPA018286, HPA020585 Enhanced Approved Nucleus
Cytosol Expressed in all Mixed testis: 38.8 Expressed in all +ALG8 MGC2840 ENSG00000159063 ALG8, alpha-1,3-glucosyltransferase 11 78100936-78139660 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA051898 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 86.2 Expressed in all +FBXW5 DKFZP434B205, Fbw5, MGC20962 ENSG00000159069 F-box and WD repeat domain containing 5 9 136940435-136944696 Predicted intracellular proteins Evidence at protein level HPA046615 Approved Approved Mitochondria Endometrial cancer:1.02e-4 (favourable), Renal cancer:4.74e-4 (favourable) Expressed in all Expressed in all testis: 163.1 Expressed in all +C21orf59 C21orf48, CILD26, FBB18, FLJ20467, Kur ENSG00000159079 Chromosome 21 open reading frame 59 21 32592079-32612866 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018453, HPA019055, HPA028849, CAB034170 Enhanced Supported Approved Rods & Rings Renal cancer:1.54e-5 (unfavourable), Endometrial cancer:8.90e-4 (favourable) Expressed in all Expressed in all testis: 77.6 Expressed in all +SYNJ1 INPP5G, PARK20 ENSG00000159082 Synaptojanin 1 21 32628759-32728048 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA011916 Enhanced Approved Nucleoplasm
Centrosome
Cytosol Prostate cancer:2.58e-4 (unfavourable), Head and neck cancer:4.43e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 65.9 testis: 18.4 Expressed in all +PAXBP1 C21orf66, fSAP105, GCFC, GCFC1 ENSG00000159086 PAX3 and PAX7 binding protein 1 21 32733899-32771858 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003757 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.50e-5 (unfavourable), Prostate cancer:9.43e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 18.7 Expressed in all +IFNAR2 IFNABR ENSG00000159110 Interferon alpha and beta receptor subunit 2 21 33229901-33265675 Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:7.54e-7 (unfavourable) Expressed in all Expressed in all spleen: 58.7 Expressed in all +MRPL10 L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8 ENSG00000159111 Mitochondrial ribosomal protein L10 17 47823272-47831534 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA021234, HPA029885 Enhanced Enhanced Mitochondria Liver cancer:6.67e-4 (unfavourable) Expressed in all Expressed in all ovary: 61.1 Expressed in all +IFNGR2 AF-1, IFNGT1 ENSG00000159128 Interferon gamma receptor 2 21 33402896-33479348 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA001535 Enhanced Approved Nucleoplasm
Golgi apparatus Renal cancer:1.13e-10 (unfavourable), Liver cancer:3.25e-4 (unfavourable) Expressed in all Mixed spleen: 10.0 Mixed +GART PGFT, PRGS ENSG00000159131 Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 21 33503931-33543491 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002119, HPA005779 Approved Uncertain Nucleoplasm
Mitochondria
Cytosol Renal cancer:3.95e-6 (unfavourable), Head and neck cancer:5.05e-5 (unfavourable), Liver cancer:9.82e-5 (unfavourable), Pancreatic cancer:2.19e-4 (unfavourable) Expressed in all Expressed in all testis: 55.1 Expressed in all +SON BASS1, C21orf50, DBP-5, FLJ21099, FLJ33914, KIAA1019, NREBP ENSG00000159140 SON DNA binding protein 21 33542618-33577481 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA023535, HPA031755, HPA031756 Supported Enhanced Nuclear speckles Expressed in all Expressed in all parathyroid gland: 223.1 Expressed in all +DONSON B17, C21orf60, C2TA, DKFZP434M035 ENSG00000159147 Downstream neighbor of SON 21 33559542-33588708 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039558, HPA049033 Uncertain Approved Nucleoplasm
Cell Junctions
Cytosol Renal cancer:0.00e+0 (unfavourable), Ovarian cancer:2.17e-4 (favourable), Liver cancer:8.22e-4 (unfavourable) Expressed in all Tissue enhanced testis: 40.3 parathyroid gland: 15.4 Expressed in all +SV2A KIAA0736, SV2 ENSG00000159164 Synaptic vesicle glycoprotein 2A 1 149903318-149917882 FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB002226, HPA007863 Enhanced Approved Cytosol Renal cancer:3.22e-4 (unfavourable) Tissue enriched Tissue enhanced cerebral cortex: 166.9;parathyroid gland: 72.0 epididymis: 28.2 Cell line enhanced NTERA-2: 65.6;SCLC-21H: 63.2 +LAD1 ENSG00000159166 Ladinin 1 1 201373244-201399915 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007256, HPA028732 Enhanced Enhanced Actin filaments Lung cancer:6.73e-4 (unfavourable) Mixed Tissue enhanced esophagus: 291.7;skin: 236.6 small intestine: 93.9 Cell line enhanced A-431: 173.4;CAPAN-2: 150.1;HaCaT: 219.8;MCF7: 165.3;RT4: 146.2;SK-BR-3: 220.4 +STC1 STC ENSG00000159167 Stanniocalcin 1 8 23841915-23854807 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB018625, HPA023918 Approved Renal cancer:1.23e-6 (unfavourable), Glioma:9.44e-5 (unfavourable), Lung cancer:1.53e-4 (unfavourable), Stomach cancer:5.55e-4 (unfavourable), Head and neck cancer:6.32e-4 (unfavourable), Cervical cancer:8.45e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 78.0 endometrium: 53.9 Cell line enhanced BJ hTERT+: 280.7;hTEC/SVTERT24-B: 201.5;U-87 MG: 608.6 +TNNI1 ENSG00000159173 Troponin I1, slow skeletal type 1 201403768-201429866 Predicted intracellular proteins Evidence at protein level HPA028190 Approved Uncertain Nucleus
Nucleoli Head and neck cancer:9.27e-4 (unfavourable) Group enriched Tissue enriched 21 skeletal muscle: 4420.6 esophagus: 206.1 Cell line enriched 12 RH-30: 471.8 +CSRP1 CSRP, CYRP, D1S181E ENSG00000159176 Cysteine and glycine rich protein 1 1 201483530-201509456 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045617 Uncertain Renal cancer:2.11e-4 (unfavourable), Head and neck cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 3310.4 Mixed +PRAC1 C17orf92, PRAC ENSG00000159182 Prostate cancer susceptibility candidate 1 17 48721719-48722522 Predicted intracellular proteins Evidence at transcript level HPA047871 Approved Tissue enriched Group enriched 38 colon: 102.9;prostate: 171.7;rectum: 220.8 urinary bladder: 4.3 Cell line enriched 32 PC-3: 343.9 +HOXB13 ENSG00000159184 Homeobox B13 17 48724763-48729178 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004438, HPA062852, HPA065019 Enhanced Enhanced Nucleoplasm Tissue enriched Tissue enhanced prostate: 115.1;rectum: 39.0 colon: 21.4 Cell line enriched 13 PC-3: 139.6 +C1QC C1QG ENSG00000159189 Complement C1q C chain 1 22643630-22648110 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001471, CAB009828 Supported Uncertain Vesicles Renal cancer:1.17e-5 (unfavourable) Expressed in all Expressed in all spleen: 1285.6 Cell line enhanced RPMI-8226: 1.7 +KCNE2 LQT6, MiRP1 ENSG00000159197 Potassium voltage-gated channel subfamily E regulatory subunit 2 21 34364024-34371389 Disease related genes, Predicted membrane proteins Evidence at protein level HPA029706, HPA051553 Enhanced Tissue enriched Tissue enriched 25 stomach: 175.3 duodenum: 7.0 Cell line enhanced SCLC-21H: 2.3 +ATP5G1 ATP5G ENSG00000159199 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C1 (subunit 9) 17 48892765-48895871 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:8.24e-6 (favourable), Cervical cancer:3.88e-4 (favourable) Expressed in all Expressed in all heart muscle: 388.5 Expressed in all +RCAN1 DSCR1 ENSG00000159200 Regulator of calcineurin 1 21 34513142-34615142 Predicted intracellular proteins Evidence at protein level CAB037218 Uncertain Approved Cytosol Expressed in all Tissue enriched 8 parathyroid gland: 1116.7 placenta: 137.4 Cell line enhanced SK-MEL-30: 987.4;WM-115: 803.4 +UBE2Z FLJ13855, USE1 ENSG00000159202 Ubiquitin conjugating enzyme E2 Z 17 48908369-48929056 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007922 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.05e-4 (unfavourable), Colorectal cancer:4.62e-4 (favourable), Liver cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 82.7 Expressed in all +CIART BC017397, C1orf51 ENSG00000159208 Circadian associated repressor of transcription 1 150282543-150287093 Predicted intracellular proteins Evidence at protein level HPA027515, HPA054349 Enhanced Supported Nucleoplasm Expressed in all Mixed seminal vesicle: 33.9 Cell line enhanced Karpas-707: 28.2 +SNF8 Dot3, EAP30, VPS22 ENSG00000159210 SNF8, ESCRT-II complex subunit 17 48929316-48945117 Predicted intracellular proteins Evidence at protein level HPA059320 Approved Supported Nucleoplasm
Cytosol Renal cancer:2.81e-7 (unfavourable), Liver cancer:7.64e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 41.0 Expressed in all +CLIC6 CLIC1L, CLIC5 ENSG00000159212 Chloride intracellular channel 6 21 34669389-34718227 Predicted intracellular proteins, Transporters Evidence at protein level HPA055123, HPA065285 Enhanced Lung cancer:3.15e-5 (favourable), Breast cancer:6.11e-5 (favourable) Mixed Tissue enhanced stomach: 79.1 cervix, uterine: 24.4 Cell line enhanced HMC-1: 2.4;NTERA-2: 3.8;T-47d: 7.2;THP-1: 2.3 +CCDC24 MGC45441 ENSG00000159214 Coiled-coil domain containing 24 1 43991359-43996528 Predicted intracellular proteins Evidence at protein level HPA035424, HPA061710 Uncertain Enhanced Plasma membrane
Cytosol Breast cancer:3.06e-5 (favourable), Liver cancer:1.70e-4 (unfavourable), Head and neck cancer:3.18e-4 (favourable) Expressed in all Tissue enhanced fallopian tube: 18.3 testis: 15.2 Cell line enhanced CAPAN-2: 11.7 +RUNX1 AML1, AMLCR1, CBFA2, PEBP2A2 ENSG00000159216 Runt related transcription factor 1 21 34787801-36004667 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004176, HPA037912 Enhanced Enhanced Nucleoplasm
Vesicles Renal cancer:3.44e-15 (unfavourable) Expressed in all Mixed breast: 34.0 Cell line enhanced HEL: 225.2 +IGF2BP1 IMP-1 ENSG00000159217 Insulin like growth factor 2 mRNA binding protein 1 17 48997412-49055650 Predicted intracellular proteins Evidence at protein level HPA021367, HPA062273 Enhanced Supported Cytosol Tissue enriched Group enriched 6 placenta: 8.0;testis: 9.1 kidney: 1.4 Cell line enhanced AF22: 145.0;CACO-2: 196.9;REH: 127.4 +GIP ENSG00000159224 Gastric inhibitory polypeptide 17 48958554-48968596 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB016729, HPA021612 Enhanced Tissue enriched Group enriched 156 duodenum: 261.3;small intestine: 93.9 stomach: 1.1 Cell line enhanced A549: 6.0;BEWO: 5.7;Hep G2: 6.5 +CBR1 CBR, SDR21C1 ENSG00000159228 Carbonyl reductase 1 21 36069941-36073166 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018433 Approved Approved Nucleus
Cytosol Breast cancer:2.18e-4 (favourable), Renal cancer:4.75e-4 (favourable) Expressed in all Expressed in all duodenum: 544.9 Mixed +CBR3 SDR21C2 ENSG00000159231 Carbonyl reductase 3 21 36134912-36146566 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018434 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:5.95e-6 (unfavourable) Expressed in all Mixed skin: 20.7 Mixed +GJD2 CX36, GJA9 ENSG00000159248 Gap junction protein delta 2 15 34751032-34754965 Predicted membrane proteins Evidence at protein level HPA014355 Uncertain Tissue enriched Group enriched 6 adrenal gland: 7.9;cerebral cortex: 1.9 pancreas: 0.8 Not detected +ACTC1 ACTC, CMD1R ENSG00000159251 Actin, alpha, cardiac muscle 1 15 34788096-34796139 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037330, HPA041264, HPA041271 Enhanced Head and neck cancer:3.72e-5 (unfavourable), Urothelial cancer:9.32e-4 (unfavourable) Group enriched Tissue enriched 10 heart muscle: 1903.0 seminal vesicle: 191.9 Group enriched 7 fHDF/TERT166: 217.0;LHCN-M2: 930.7;RH-30: 512.0 +MORC3 KIAA0136, NXP2, ZCW5, ZCWCC3 ENSG00000159256 MORC family CW-type zinc finger 3 21 36320189-36386148 Predicted intracellular proteins Evidence at protein level HPA018406, HPA034848 Approved Enhanced Nucleoplasm
Mitochondria Expressed in all Expressed in all endometrium: 30.9 Expressed in all +CHAF1B CAF-1, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7 ENSG00000159259 Chromatin assembly factor 1 subunit B 21 36385378-36419015 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021679, CAB033604 Enhanced Supported Nucleoplasm Liver cancer:6.14e-6 (unfavourable), Cervical cancer:5.44e-5 (favourable), Colorectal cancer:7.92e-4 (favourable) Expressed in all Mixed testis: 5.4 Expressed in all +CLDN14 DFNB29 ENSG00000159261 Claudin 14 21 36460621-36576569 Disease related genes, Predicted membrane proteins Evidence at protein level HPA054707 Uncertain Vesicles Liver cancer:1.53e-4 (favourable) Tissue enriched Group enriched 11 kidney: 3.6;liver: 9.5 gallbladder: 0.6 Cell line enriched 18 HDLM-2: 205.9 +SIM2 bHLHe15, MGC119447, SIM ENSG00000159263 Single-minded family bHLH transcription factor 2 21 36699133-36749917 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029295 Approved Supported Nucleoplasm
Nuclear bodies Endometrial cancer:2.10e-4 (unfavourable), Urothelial cancer:2.88e-4 (favourable) Tissue enhanced Tissue enhanced esophagus: 22.8;kidney: 13.0;prostate: 10.3 stomach: 5.1 Cell line enhanced PC-3: 40.7;RPTEC TERT1: 41.3;RT4: 26.9 +HLCS HCS ENSG00000159267 Holocarboxylase synthetase 21 36750888-36990236 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017379 Approved Supported Cytosol Breast cancer:7.72e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.7 Expressed in all +GOLGA6A GLP, GOLGA6 ENSG00000159289 Golgin A6 family member A 15 74069857-74082550 Predicted intracellular proteins Evidence at protein level HPA044978, HPA050087 Supported Not detected Tissue enriched 9 testis: 19.6 liver: 2.1 Cell line enhanced U-266/70: 1.0 +SCUBE1 ENSG00000159307 Signal peptide, CUB domain and EGF like domain containing 1 22 43197283-43343388 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003190 Approved Mixed Tissue enhanced ovary: 24.9 testis: 13.8 Cell line enhanced AN3-CA: 7.2;HMC-1: 43.8;THP-1: 13.8 +ARHGAP27 CAMGAP1, FLJ43547, SH3D20, SH3P20 ENSG00000159314 Rho GTPase activating protein 27 17 45393902-45434421 Predicted intracellular proteins Evidence at protein level HPA023919, HPA053053 Approved Supported Nucleus
Cytosol Urothelial cancer:3.21e-4 (favourable) Expressed in all Mixed esophagus: 14.0 Cell line enhanced BEWO: 16.1;RT4: 20.7 +ADPGK ADP-GK, DKFZp434B195 ENSG00000159322 ADP dependent glucokinase 15 72751369-72785846 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045194, HPA058525 Approved Approved Centrosome Renal cancer:4.52e-7 (unfavourable), Prostate cancer:2.22e-4 (unfavourable) Expressed in all Mixed lung: 25.1 Expressed in all +PTMS ParaT ENSG00000159335 Parathymosin 12 6765516-6770952 Predicted intracellular proteins Evidence at protein level HPA038186 Approved Approved Nucleus
Nucleoli Renal cancer:6.18e-5 (unfavourable) Expressed in all Expressed in all prostate: 136.1 Expressed in all +PLA2G4D cPLA2delta ENSG00000159337 Phospholipase A2 group IVD 15 42067009-42094554 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Mixed Group enriched 29 prostate: 34.2;skin: 16.5 esophagus: 0.8 Cell line enriched 30 RPMI-8226: 12.2 +PADI4 PAD, PADI5, PDI4, PDI5 ENSG00000159339 Peptidyl arginine deiminase 4 1 17308195-17364004 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017007, HPA042825 Enhanced Not detected Tissue enriched 12 bone marrow: 71.8 spleen: 5.9 Cell line enhanced HEL: 1.1;RPMI-8226: 1.0 +ADIPOR1 ACDCR1, PAQR1 ENSG00000159346 Adiponectin receptor 1 1 202940823-202958572 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Ovarian cancer:5.27e-4 (favourable), Pancreatic cancer:5.50e-4 (unfavourable) Expressed in all Expressed in all placenta: 136.6 Expressed in all +CYB5R1 humb5R2, NQO3A2 ENSG00000159348 Cytochrome b5 reductase 1 1 202961869-202967280 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010641, HPA014147 Enhanced Uncertain Nucleoli
Mitochondria
Cytosol Endometrial cancer:1.14e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 183.8 Expressed in all +PSMD4 AF, AF-1, Rpn10, S5A ENSG00000159352 Proteasome 26S subunit, non-ATPase 4 1 151254703-151267479 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA038807, HPA039252, CAB047300 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:6.66e-10 (unfavourable) Expressed in all Expressed in all testis: 174.0 Expressed in all +ATP13A2 CLN12, HSA9947, PARK9 ENSG00000159363 ATPase 13A2 1 16985958-17011928 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB037038, CAB037111, HPA050910, HPA054717 Approved Liver cancer:3.33e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 74.8 Expressed in all +M1AP C2orf65, D6Mm5e, SPATA37 ENSG00000159374 Meiosis 1 associated protein 2 74557883-74648338 Predicted intracellular proteins Evidence at protein level HPA045420, HPA059302 Uncertain Approved Nucleoli
Mitochondria Mixed Tissue enhanced testis: 14.8 fallopian tube: 4.2 Group enriched 10 NTERA-2: 2.1;RT4: 1.6 +PSMB4 HN3, PROS26 ENSG00000159377 Proteasome subunit beta 4 1 151399534-151401944 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006700 Approved Approved Intermediate filaments
Centrosome
Cytosol Renal cancer:2.90e-10 (unfavourable), Liver cancer:7.45e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 275.5 Expressed in all +IRX6 IRX-3, IRX7 ENSG00000159387 Iroquois homeobox 6 16 55323760-55330760 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA018332 Uncertain Approved Nucleus
Mitochondria Lung cancer:3.34e-4 (favourable) Tissue enhanced Tissue enhanced adipose tissue: 8.6;heart muscle: 4.9 skin: 3.3 Cell line enhanced AF22: 1.3;HEK 293: 1.5;RPTEC TERT1: 4.5;SK-MEL-30: 3.0 +BTG2 APRO1, MGC126063, MGC126064, PC3, TIS21 ENSG00000159388 BTG anti-proliferation factor 2 1 203305491-203309602 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA002355 Uncertain Approved Nucleoplasm
Vesicles Breast cancer:8.53e-4 (favourable) Expressed in all Expressed in all ovary: 666.8 Cell line enhanced HMC-1: 140.5;U-266/70: 189.1 +CES5A CAUXIN, CES4C1, CES5, CES7, FLJ31547 ENSG00000159398 Carboxylesterase 5A 16 55846154-55956031 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA047635 Uncertain Tissue enhanced Tissue enriched 40 epididymis: 79.9 liver: 1.9 Cell line enriched 29 U-266/70: 5.8 +HK2 ENSG00000159399 Hexokinase 2 2 74833981-74893359 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028587 Enhanced Renal cancer:1.37e-4 (unfavourable), Liver cancer:3.65e-4 (unfavourable) Expressed in all Mixed epididymis: 80.4 Cell line enhanced U-87 MG: 168.5 +C1R ENSG00000159403 Complement C1r 12 7080209-7092607 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001251, HPA001551 Uncertain Uncertain Nucleoplasm
Cytosol Renal cancer:1.94e-14 (unfavourable) Expressed in all Expressed in all liver: 1226.4 Cell line enhanced ASC diff: 1273.8;ASC TERT1: 658.4;BJ hTERT+: 685.9;BJ hTERT+ SV40 Large T+ RasG12V: 496.0;HSkMC: 797.4 +CELF3 BRUNOL1, CAGH4, ERDA4, MGC57297, TNRC4 ENSG00000159409 CUGBP Elav-like family member 3 1 151702404-151716814 Predicted intracellular proteins Evidence at protein level HPA006292 Uncertain Approved Nucleoplasm Group enriched Group enriched 6 adrenal gland: 15.2;cerebral cortex: 51.7 stomach: 5.5 Group enriched 10 SCLC-21H: 50.0;SH-SY5Y: 31.5 +ALDH4A1 ALDH4, P5CDh ENSG00000159423 Aldehyde dehydrogenase 4 family member A1 1 18871430-18902781 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004645, HPA006401 Enhanced Cervical cancer:5.06e-4 (favourable) Expressed in all Tissue enhanced kidney: 185.7;liver: 108.1 adipose tissue: 63.8 Expressed in all +STARD9 KIAA1300, KIF16A ENSG00000159433 StAR related lipid transfer domain containing 9 15 42575659-42720981 Predicted intracellular proteins Evidence at protein level HPA014562, HPA038631 Uncertain Supported Microtubules Mixed Mixed testis: 14.4 Mixed +THEM4 CTMP ENSG00000159445 Thioesterase superfamily member 4 1 151873584-151909808 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028161 Approved Liver cancer:1.38e-4 (unfavourable), Pancreatic cancer:2.51e-4 (favourable) Expressed in all Expressed in all epididymis,kidney: 11.6 Mixed +TCHH THH ENSG00000159450 Trichohyalin 1 152106317-152115454 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028375 Uncertain Tissue enhanced Tissue enhanced placenta: 1.6;spleen: 2.1 testis: 1.2 Cell line enhanced HaCaT: 3.2;SCLC-21H: 1.3;THP-1: 1.3 +LCE2B LEP10, SPRL1B, XP5 ENSG00000159455 Late cornified envelope 2B 1 152686123-152687401 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 10 skin: 564.7 breast: 56.0 Not detected +UBR1 ENSG00000159459 Ubiquitin protein ligase E3 component n-recognin 1 15 42942897-43106113 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038838 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 27.4 Expressed in all +AMFR gp78, RNF45 ENSG00000159461 Autocrine motility factor receptor 16 56361452-56425538 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB026381, HPA029018, HPA077835 Approved Supported Endoplasmic reticulum
Golgi apparatus Expressed in all Expressed in all testis: 154.7 Expressed in all +MED8 ARC32, MGC17544, MGC19641 ENSG00000159479 Mediator complex subunit 8 1 43383917-43389808 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028377, HPA028438 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:1.11e-7 (unfavourable), Liver cancer:2.04e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 41.6 Expressed in all +TGM7 TGMZ ENSG00000159495 Transglutaminase 7 15 43276280-43302255 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at transcript level Tissue enriched Group enriched 5 testis: 1.5;tonsil: 1.5 esophagus: 0.2 Cell line enriched 33 EFO-21: 3.3 +RGL4 Rgr ENSG00000159496 Ral guanine nucleotide dissociation stimulator like 4 22 23688136-23699176 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035979 Uncertain Approved Centrosome Not detected Tissue enriched 8 bone marrow: 107.4 lymph node: 12.9 Cell line enhanced MOLT-4: 21.0;U-937: 47.3 +SPRR2G ENSG00000159516 Small proline rich protein 2G 1 153149582-153150869 Predicted intracellular proteins Evidence at transcript level Group enriched Tissue enriched 10 skin: 271.7 tonsil: 27.2 Cell line enriched 12 hTCEpi: 2.5 +PGLYRP3 PGLYRPIalpha, PGRP-Ialpha, PGRPIA ENSG00000159527 Peptidoglycan recognition protein 3 1 153297862-153310718 Predicted secreted proteins Evidence at protein level HPA030369 Uncertain Tissue enhanced Group enriched 9 esophagus: 42.8;skin: 87.1 tonsil: 6.8 Group enriched 15 HaCaT: 3.4;HDLM-2: 1.4;hTCEpi: 1.0 +ISL2 FLJ10160 ENSG00000159556 ISL LIM homeobox 2 15 76336724-76342476 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA075192 Approved Rods & Rings Mixed Not detected prostate: 0.9 Cell line enhanced HEK 293: 13.3 +RSPRY1 KIAA1972 ENSG00000159579 Ring finger and SPRY domain containing 1 16 57186137-57240475 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003729 Approved Head and neck cancer:8.21e-5 (unfavourable) Expressed in all Expressed in all testis: 39.7 Expressed in all +CCDC17 FLJ33084 ENSG00000159588 Coiled-coil domain containing 17 1 45620044-45624057 Predicted intracellular proteins Evidence at protein level HPA028338 Enhanced Tissue enhanced Tissue enriched 17 fallopian tube: 54.5 lung: 3.2 Not detected +GPBP1L1 SP192 ENSG00000159592 GC-rich promoter binding protein 1 like 1 1 45627304-45688113 Predicted intracellular proteins Evidence at protein level HPA028593 Approved Approved Nucleoplasm
Plasma membrane
Focal adhesion sites Expressed in all Expressed in all testis: 107.1 Expressed in all +NAE1 APP-BP1, APPBP1, ula-1 ENSG00000159593 NEDD8 activating enzyme E1 subunit 1 16 66802875-66873256 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041178, HPA042041 Enhanced Approved Nucleus
Microtubules
Centrosome Liver cancer:3.92e-8 (unfavourable), Thyroid cancer:9.44e-5 (favourable) Expressed in all Expressed in all testis: 86.4 Expressed in all +TMEM69 C1orf154, FLJ21029 ENSG00000159596 Transmembrane protein 69 1 45687214-45694443 Predicted membrane proteins Evidence at transcript level HPA026993 Approved Approved Nucleoplasm Liver cancer:3.66e-8 (unfavourable), Breast cancer:2.24e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.9 Expressed in all +ADGRG5 GPR114, PGR27 ENSG00000159618 Adhesion G protein-coupled receptor G5 16 57542421-57591681 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007133 Enhanced Approved Nucleoplasm
Nuclear membrane
Vesicles Cervical cancer:4.25e-4 (favourable) Mixed Tissue enhanced lymph node: 11.2;tonsil: 8.8 appendix,spleen: 5.9 Cell line enriched 8 HMC-1: 31.8 +DRC7 C16orf50, CCDC135, CFAP50, DKFZp434I099, FAP50 ENSG00000159625 Dynein regulatory complex subunit 7 16 57694793-57731805 Predicted intracellular proteins Evidence at protein level Endometrial cancer:3.61e-4 (favourable) Tissue enhanced Group enriched 18 fallopian tube: 32.4;testis: 81.2 parathyroid gland: 3.2 Cell line enhanced Hep G2: 2.0 +ACE ACE1, CD143, DCP1 ENSG00000159640 Angiotensin I converting enzyme 17 63477061-63498380 Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002426, CAB002921, HPA029298, HPA069790 Enhanced Approved Vesicles Expressed in all Tissue enhanced duodenum: 178.9;small intestine: 291.6 testis: 83.7 Cell line enhanced ASC TERT1: 44.4;HUVEC TERT2: 28.2 +TEPP ENSG00000159648 Testis, prostate and placenta expressed 16 57976435-57988116 Predicted secreted proteins Evidence at protein level HPA062092 Enhanced Tissue enhanced Tissue enriched 9 testis: 7.3 thyroid gland: 0.8 Not detected +UROC1 FLJ31300, HMFN0320 ENSG00000159650 Urocanate hydratase 1 3 126481281-126517773 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA069863 Enhanced Tissue enriched Tissue enriched 126 liver: 43.0 fallopian tube: 0.3 Cell line enriched 7 NB-4: 2.6 +EFCAB14 KIAA0494 ENSG00000159658 EF-hand calcium binding domain 14 1 46675159-46719064 Predicted membrane proteins Evidence at protein level HPA011224, HPA011938 Supported Approved Nucleoli
Golgi apparatus
Cytosol Expressed in all Expressed in all parathyroid gland: 305.3 Expressed in all +SPON2 DIL1 ENSG00000159674 Spondin 2 4 1166932-1208962 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040170, HPA066095 Uncertain Approved Vesicles Endometrial cancer:2.03e-4 (favourable), Urothelial cancer:9.22e-4 (unfavourable) Tissue enriched Tissue enhanced endometrium: 105.2;prostate: 113.0 cervix, uterine: 53.6 Group enriched 6 HHSteC: 216.0;HSkMC: 330.1 +CHCHD6 CHCM1, MGC13016, Mic25, PPP1R23 ENSG00000159685 Coiled-coil-helix-coiled-coil-helix domain containing 6 3 126704220-126960406 Predicted intracellular proteins Evidence at protein level HPA047673, HPA051975 Approved Supported Mitochondria Renal cancer:6.76e-4 (favourable), Cervical cancer:7.46e-4 (favourable) Expressed in all Expressed in all testis: 48.8 Expressed in all +CTBP1 BARS ENSG00000159692 C-terminal binding protein 1 4 1211448-1249953 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004217, HPA018987, HPA044971 Approved Enhanced Nucleoplasm Endometrial cancer:4.03e-4 (favourable), Urothelial cancer:8.94e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 141.8 Expressed in all +LRRC36 FLJ11004 ENSG00000159708 Leucine rich repeat containing 36 16 67326798-67385203 Predicted intracellular proteins Evidence at protein level HPA055237, HPA058479 Enhanced Mixed Tissue enriched 7 testis: 62.5 placenta: 8.8 Cell line enhanced hTEC/SVTERT24-B: 1.4 +TPPP3 CGI-38, p20, p25gamma ENSG00000159713 Tubulin polymerization promoting protein family member 3 16 67389809-67393535 Predicted intracellular proteins Evidence at protein level HPA047629 Approved Approved Nucleoli fibrillar center Renal cancer:8.84e-4 (unfavourable) Expressed in all Tissue enriched 6 fallopian tube: 1311.7 lung: 213.8 Cell line enhanced A549: 51.8;RH-30: 29.0;SCLC-21H: 54.1;SH-SY5Y: 21.0 +ZDHHC1 C16orf1, HSU90653, ZNF377 ENSG00000159714 Zinc finger DHHC-type containing 1 16 67394419-67416833 Enzymes, Predicted membrane proteins Evidence at transcript level HPA042531, HPA048659 Uncertain Approved Cytosol Endometrial cancer:1.25e-6 (favourable), Renal cancer:1.55e-6 (favourable), Pancreatic cancer:5.99e-4 (favourable) Expressed in all Mixed fallopian tube: 31.8 Mixed +ATP6V0D1 ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD ENSG00000159720 ATPase H+ transporting V0 subunit d1 16 67438014-67481237 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA016938 Uncertain Renal cancer:1.76e-8 (favourable), Pancreatic cancer:1.20e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 187.1 Expressed in all +AGRP Agrt, ART, ASIP2 ENSG00000159723 Agouti related neuropeptide 16 67482571-67483813 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA041017 Uncertain Supported Mixed Group enriched 5 adrenal gland: 5.8;epididymis: 24.7 lung: 3.0 Not detected +ZFYVE28 KIAA1643 ENSG00000159733 Zinc finger FYVE-type containing 28 4 2269582-2418663 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038175, HPA057587 Approved Approved Nucleus
Plasma membrane
Cytosol Renal cancer:1.35e-6 (favourable) Mixed Mixed cerebral cortex: 9.9 Mixed +CARMIL2 LRRC16C, RLTPR ENSG00000159753 Capping protein regulator and myosin 1 linker 2 16 67644919-67657569 Predicted intracellular proteins Evidence at protein level HPA041402 Approved Mixed Tissue enhanced appendix: 16.2;lymph node: 25.0;spleen: 15.1 tonsil: 10.1 Cell line enhanced Daudi: 45.8;MOLT-4: 51.3;REH: 96.9;RPMI-8226: 40.2;U-698: 73.2 +C16orf86 FLJ41802 ENSG00000159761 Chromosome 16 open reading frame 86 16 67666816-67668758 Predicted intracellular proteins Evidence at protein level HPA073475 Enhanced Renal cancer:2.12e-7 (favourable), Pancreatic cancer:1.47e-4 (favourable) Expressed in all Tissue enriched 7 testis: 27.5 parathyroid gland: 3.9 Cell line enhanced HSkMC: 2.4 +PIP GCDFP-15, GCDFP15, GPIP4 ENSG00000159763 Prolactin induced protein 7 143132077-143139746 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB002661, HPA009177 Enhanced Renal cancer:5.96e-5 (favourable) Tissue enriched Group enriched 618 breast: 4504.1;salivary gland: 6904.2;seminal vesicle: 4198.4 cervix, uterine: 8.4 Cell line enriched 415 T-47d: 649.3 +FAM131B KIAA0773 ENSG00000159784 Family with sequence similarity 131 member B 7 143353400-143362770 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA021371, HPA029992 Enhanced Nucleoplasm
Cytosol Tissue enriched Tissue enriched 8 cerebral cortex: 63.8 parathyroid gland: 7.5 Cell line enhanced CACO-2: 11.5;NTERA-2: 22.2;PC-3: 19.9;SCLC-21H: 25.4 +RGS12 ENSG00000159788 Regulator of G-protein signaling 12 4 3293028-3439913 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054646, HPA067421 Supported Nucleus
Nucleoli Head and neck cancer:7.03e-4 (favourable), Renal cancer:8.43e-4 (favourable) Expressed in all Mixed cerebral cortex: 20.7 Mixed +PSKH1 ENSG00000159792 Protein serine kinase H1 16 67893272-67929678 Enzymes, Predicted membrane proteins Evidence at protein level HPA053927 Approved Approved Nucleoplasm Renal cancer:4.28e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 49.5 Expressed in all +ZYX ENSG00000159840 Zyxin 7 143381080-143391111 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004835, CAB009321, HPA073497, CAB075747 Approved Supported Focal adhesion sites Renal cancer:7.92e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 391.0 Expressed in all +ABR MDB ENSG00000159842 Active BCR-related 17 1003518-1229021 Predicted intracellular proteins Evidence at protein level HPA053618, HPA054824 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:2.21e-4 (favourable), Cervical cancer:4.03e-4 (favourable) Expressed in all Mixed smooth muscle: 12.6 Cell line enhanced Daudi: 26.9;LHCN-M2: 20.5;TIME: 33.6;U-251 MG: 34.7;U-698: 21.1 +LYPD5 FLJ30469 ENSG00000159871 LY6/PLAUR domain containing 5 19 43795929-43827206 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042511, HPA054670 Approved Approved Nucleoplasm
Cytosol Cervical cancer:5.84e-4 (favourable) Tissue enhanced Tissue enhanced skin: 43.7 testis: 12.3 Cell line enhanced A-431: 3.3;BEWO: 5.5;HaCaT: 5.3 +CCDC117 FLJ33814 ENSG00000159873 Coiled-coil domain containing 117 22 28772674-28789301 Predicted intracellular proteins Evidence at protein level HPA000826 Uncertain Approved Nucleus
Microtubules
Cytosol Mixed Expressed in all testis: 67.8 Expressed in all +ZNF230 FDZF2 ENSG00000159882 Zinc finger protein 230 19 44002948-44013926 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006172 Approved Mitochondria Mixed Mixed ovary: 5.2 Mixed +CCDC107 MGC31967 ENSG00000159884 Coiled-coil domain containing 107 9 35658290-35661511 Predicted membrane proteins Evidence at protein level HPA016857, HPA050442 Enhanced Nucleoplasm
Plasma membrane Expressed in all Expressed in all adipose tissue: 63.7 Expressed in all +ZNF222 ENSG00000159885 Zinc finger protein 222 19 44025342-44033112 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004086 Approved Approved Nucleoplasm
Nuclear bodies Pancreatic cancer:5.56e-7 (favourable) Expressed in all Mixed testis: 16.9 Mixed +NPR2 AMDM, ANPb, ANPRB, GUCY2B, NPRB ENSG00000159899 Natriuretic peptide receptor 2 9 35792154-35809732 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Expressed in all Mixed endometrium: 31.1 Cell line enhanced ASC diff: 37.7 +ZNF221 ENSG00000159905 Zinc finger protein 221 19 43951223-43967709 Predicted intracellular proteins Evidence at transcript level HPA059435 Uncertain Approved Nuclear bodies Mixed Mixed parathyroid gland: 5.1 Mixed +ZNF233 FLJ38032 ENSG00000159915 Zinc finger protein 233 19 44259880-44275317 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA020975 Uncertain Approved Nucleoplasm Mixed Tissue enhanced testis: 26.1 cerebral cortex: 5.8 Mixed +ZNF235 ANF270, HZF6, ZFP93, ZNF270 ENSG00000159917 Zinc finger protein 235 19 44228729-44305046 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045582 Uncertain Supported Nucleoplasm Mixed Mixed parathyroid gland: 5.1 Mixed +GNE IBM2, Uae1 ENSG00000159921 Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 9 36214441-36277056 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007045, HPA027258 Approved Supported Cytosol Renal cancer:9.28e-11 (favourable) Expressed in all Expressed in all rectum: 53.4 Cell line enhanced RPTEC TERT1: 82.9 +TNFRSF13C BAFFR, CD268 ENSG00000159958 TNF receptor superfamily member 13C 22 41922023-41926818 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level HPA003246, CAB008380 Enhanced Uncertain Nucleus Cervical cancer:4.44e-7 (favourable) Mixed Group enriched 10 appendix: 22.9;lymph node: 46.1;spleen: 43.5;tonsil: 49.9 bone marrow: 4.0 Cell line enhanced REH: 19.1;U-698: 7.7 +OR3A3 OR17-137, OR17-16, OR17-201, OR3A6, OR3A7, OR3A8P ENSG00000159961 Olfactory receptor family 3 subfamily A member 3 17 3420568-3421533 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected gallbladder,lymph node,tonsil: 0.1 Cell line enriched 10 HDLM-2: 1.5 +ARHGAP35 GRF-1, GRLF1, KIAA1722, P190A, p190ARhoGAP, p190RhoGAP ENSG00000160007 Rho GTPase activating protein 35 19 46918676-47005077 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB037311, HPA055184, HPA056470 Approved Supported Nuclear bodies
Aggresome Renal cancer:5.55e-8 (favourable) Expressed in all Expressed in all testis: 76.2 Expressed in all +PTGIR IP ENSG00000160013 Prostaglandin I2 (prostacyclin) receptor (IP) 19 46620468-46625118 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Renal cancer:2.09e-8 (unfavourable), Testis cancer:1.74e-4 (unfavourable) Mixed Tissue enhanced lung: 13.9 appendix: 8.2 Cell line enhanced BJ: 9.0;BJ hTERT+: 9.8;fHDF/TERT166: 11.8;HEL: 25.3 +CALM3 PHKD ENSG00000160014 Calmodulin 3 19 46601074-46610793 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level HPA044999 Approved Lung cancer:2.07e-4 (unfavourable), Thyroid cancer:9.10e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1313.4 Expressed in all +DFFA DFF-45, DFF1, DFF45, ICAD ENSG00000160049 DNA fragmentation factor subunit alpha 1 10456522-10472526 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002679, HPA018859, HPA019938, HPA025230 Supported Supported Plasma membrane
Cytosol Renal cancer:1.57e-9 (favourable), Liver cancer:9.46e-4 (unfavourable) Expressed in all Expressed in all placenta: 28.8 Expressed in all +CCDC28B MGC1203, RP4-622L5.5 ENSG00000160050 Coiled-coil domain containing 28B 1 32200386-32205387 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028589 Uncertain Pancreatic cancer:1.10e-5 (favourable), Breast cancer:2.92e-4 (favourable) Expressed in all Tissue enhanced skeletal muscle: 40.8 testis: 22.7 Mixed +IQCC FLJ10547 ENSG00000160051 IQ motif containing C 1 32205661-32208687 Predicted intracellular proteins Evidence at protein level HPA028602, HPA028686 Approved Supported Vesicles Pancreatic cancer:8.23e-5 (favourable), Testis cancer:3.79e-4 (favourable), Lung cancer:5.65e-4 (favourable) Expressed in all Tissue enhanced testis: 11.6 thyroid gland: 6.0 Mixed +TMEM234 C1orf91, dJ622L5.7, FLJ90779, RP4-622L5 ENSG00000160055 Transmembrane protein 234 1 32214472-32222359 Predicted membrane proteins, Transporters Evidence at protein level HPA015049 Uncertain Approved Vesicles Liver cancer:2.35e-5 (unfavourable), Renal cancer:4.12e-5 (unfavourable) Expressed in all Mixed epididymis: 12.8 Expressed in all +BSDC1 FLJ10276, RP4-811H24.7 ENSG00000160058 BSD domain containing 1 1 32365103-32394731 Predicted intracellular proteins Evidence at protein level HPA031358, HPA031360 Approved Enhanced Golgi apparatus Head and neck cancer:8.82e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 113.4 Expressed in all +ZBTB8A BOZF1, FLJ90065, ZBTB8, ZNF916A ENSG00000160062 Zinc finger and BTB domain containing 8A 1 32539427-32605939 Predicted intracellular proteins Evidence at protein level HPA031768, HPA031769, HPA031770 Approved Approved Nuclear speckles
Focal adhesion sites Expressed in all Mixed endometrium: 10.3 Mixed +ATAD3B KIAA1273, TOB3 ENSG00000160072 ATPase family, AAA domain containing 3B 1 1471769-1497848 Predicted intracellular proteins Evidence at protein level HPA058968, HPA064867, HPA065305 Approved Supported Mitochondria Renal cancer:5.48e-9 (unfavourable), Liver cancer:1.81e-5 (unfavourable) Expressed in all Mixed appendix: 7.5 Mixed +SSU72 HSPC182 ENSG00000160075 SSU72 homolog, RNA polymerase II CTD phosphatase 1 1541673-1574869 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069290, HPA070604 Enhanced Approved Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 149.3 Expressed in all +UBE2J2 NCUBE2, Ubc6p ENSG00000160087 Ubiquitin conjugating enzyme E2 J2 1 1253909-1273885 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.00e-4 (unfavourable) Expressed in all Expressed in all testis: 115.2 Expressed in all +ZNF362 FLJ25476, lin-29, RN ENSG00000160094 Zinc finger protein 362 1 33256545-33300719 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059239 Uncertain Approved Nucleus
Nucleoli Expressed in all Expressed in all spleen: 22.1 Expressed in all +FNDC5 FRCP2 ENSG00000160097 Fibronectin type III domain containing 5 1 32862268-32872482 Predicted membrane proteins Evidence at protein level HPA051290 Approved Group enriched Tissue enhanced skeletal muscle: 110.2 heart muscle: 26.5 Cell line enhanced RH-30: 45.0;SCLC-21H: 9.3 +CPAMD8 K-CAP, KIAA1283, VIP ENSG00000160111 C3 and PZP like, alpha-2-macroglobulin domain containing 8 19 16892947-17026815 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031327, HPA031328, HPA031330 Uncertain Mixed Tissue enhanced prostate: 25.1;seminal vesicle: 52.1 lung: 22.8 Group enriched 10 BEWO: 18.7;EFO-21: 11.7;T-47d: 32.2 +NR2F6 EAR-2, ERBAL2 ENSG00000160113 Nuclear receptor subfamily 2 group F member 6 19 17231883-17245940 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Endometrial cancer:4.36e-4 (unfavourable) Expressed in all Mixed duodenum: 30.9 Expressed in all +ANKLE1 ANKRD41, FLJ39369, LEMD6 ENSG00000160117 Ankyrin repeat and LEM domain containing 1 19 17281645-17287646 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026789, HPA073498 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:4.86e-5 (unfavourable) Mixed Tissue enhanced bone marrow: 13.7 lymph node: 3.6 Cell line enhanced Daudi: 47.2;U-937: 40.1 +CCDC58 FLJ33273 ENSG00000160124 Coiled-coil domain containing 58 3 122359591-122383231 Predicted intracellular proteins Evidence at protein level HPA047777, HPA051965 Approved Approved Nucleoli
Mitochondria Liver cancer:2.94e-5 (unfavourable), Endometrial cancer:1.53e-4 (unfavourable), Urothelial cancer:7.29e-4 (favourable) Expressed in all Expressed in all kidney: 47.4 Expressed in all +VMA21 MEAX, XMEA ENSG00000160131 VMA21, vacuolar ATPase assembly factor X 151396515-151409364 Disease related genes, Predicted membrane proteins Evidence at protein level HPA010972 Uncertain Cervical cancer:2.30e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 30.0 Expressed in all +KALRN ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD ENSG00000160145 Kalirin, RhoGEF kinase 3 124080023-124726325 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011913, CAB026456 Approved Supported Nucleoplasm
Cytosol Mixed Tissue enhanced cerebral cortex: 51.3 spleen: 11.8 Cell line enhanced CACO-2: 47.6;HEL: 31.9;SH-SY5Y: 16.9 +CILP2 MGC45771 ENSG00000160161 Cartilage intermediate layer protein 2 19 19538248-19546659 Predicted secreted proteins Evidence at protein level HPA041847 Uncertain Endometrial cancer:3.22e-6 (unfavourable), Ovarian cancer:2.50e-4 (unfavourable) Mixed Tissue enhanced gallbladder: 2.5;testis: 4.2 adipose tissue: 0.8 Cell line enhanced ASC diff: 3.2;HEK 293: 2.6 +ABCG1 ABC8 ENSG00000160179 ATP binding cassette subfamily G member 1 21 42199689-42297244 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA031470, HPA031471 Approved Supported Golgi apparatus
Vesicles Renal cancer:7.16e-6 (favourable) Expressed in all Expressed in all lung: 43.5 Cell line enhanced MCF7: 25.3;MOLT-4: 25.1;SCLC-21H: 26.2 +TFF3 HITF, ITF ENSG00000160180 Trefoil factor 3 21 42311667-42315651 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB020681, HPA035464 Enhanced Approved Nucleus
Nucleoli Endometrial cancer:5.60e-6 (favourable) Expressed in all Tissue enhanced cervix, uterine: 470.7;colon: 496.2;rectum: 504.3;thyroid gland: 620.1 small intestine: 457.0 Cell line enhanced MCF7: 63.2;SCLC-21H: 28.3;T-47d: 35.0;TIME: 85.5 +TFF2 SML1 ENSG00000160181 Trefoil factor 2 21 42346357-42351128 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB025834, HPA036705 Enhanced Liver cancer:1.99e-4 (unfavourable) Group enriched Group enriched 29 duodenum: 1027.1;stomach: 5110.7 gallbladder: 107.1 Group enriched 20 CAPAN-2: 32.8;PC-3: 124.0 +TFF1 BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 ENSG00000160182 Trefoil factor 1 21 42362282-42366594 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB002170, HPA003425 Enhanced Breast cancer:5.00e-4 (favourable), Endometrial cancer:5.67e-4 (favourable) Group enriched Tissue enriched 32 stomach: 6419.9 gallbladder: 203.1 Cell line enriched 49 MCF7: 8447.1 +TMPRSS3 DFNB10, DFNB8 ENSG00000160183 Transmembrane protease, serine 3 21 42371890-42396846 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Colorectal cancer:3.64e-4 (unfavourable), Renal cancer:8.24e-4 (unfavourable) Mixed Tissue enhanced fallopian tube: 35.2 stomach: 13.7 Cell line enhanced HEL: 58.2;SiHa: 35.3;U-266/84: 182.5 +UBASH3A CLIP4, STS-2, TULA ENSG00000160185 Ubiquitin associated and SH3 domain containing A 21 42403447-42447681 Predicted intracellular proteins Evidence at protein level HPA035367 Supported Nucleoplasm
Golgi apparatus Mixed Tissue enhanced lymph node: 12.5 appendix: 6.7 Group enriched 6 HEL: 20.6;MOLT-4: 38.2 +RSPH1 CILD24, FLJ32753, RSP44, RSPH10A, TSGA2 ENSG00000160188 Radial spoke head 1 homolog 21 42472486-42496354 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA016816, HPA017382 Enhanced Approved Nucleoplasm Tissue enhanced Tissue enriched 6 fallopian tube: 251.8 testis: 42.3 Cell line enhanced HEL: 4.8;MCF7: 8.1;RPTEC TERT1: 11.5 +SLC37A1 ENSG00000160190 Solute carrier family 37 member 1 21 42496008-42581440 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA030418, CAB034154 Approved Thyroid cancer:3.43e-5 (favourable), Endometrial cancer:9.22e-5 (favourable) Expressed in all Mixed duodenum: 45.6 Cell line enhanced HEL: 112.3 +PDE9A ENSG00000160191 Phosphodiesterase 9A 21 42653636-42775509 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011380 Enhanced Approved Nucleoplasm
Vesicles Expressed in all Tissue enhanced prostate: 56.8 spleen: 25.5 Cell line enhanced AF22: 29.5;EFO-21: 28.2;NTERA-2: 41.2;SCLC-21H: 26.8 +WDR4 TRM82, TRMT82 ENSG00000160193 WD repeat domain 4 21 42843094-42879568 Predicted intracellular proteins Evidence at protein level HPA017381 Uncertain Supported Nucleus
Cytosol Liver cancer:5.48e-7 (unfavourable) Expressed in all Mixed lymph node: 10.9 Expressed in all +NDUFV3 CI-10k ENSG00000160194 NADH:ubiquinone oxidoreductase subunit V3 21 42879644-42913304 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019791, HPA020463, HPA030427, CAB034142 Enhanced Enhanced Mitochondria Expressed in all Expressed in all skeletal muscle: 29.0 Expressed in all +PKNOX1 PREP1 ENSG00000160199 PBX/knotted 1 homeobox 1 21 42974510-43033931 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004285, HPA057215, HPA065017 Approved Enhanced Nucleoplasm Liver cancer:4.54e-8 (unfavourable), Pancreatic cancer:6.71e-4 (favourable) Expressed in all Mixed thyroid gland: 16.8 Expressed in all +CBS HIP4 ENSG00000160200 Cystathionine-beta-synthase 21 43053191-43076943 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001223 Supported Approved Nucleoli
Vesicles Mixed Tissue enhanced liver: 56.6;ovary: 31.1 cerebral cortex: 19.8 Cell line enhanced HAP1: 171.2;HHSteC: 181.6 +U2AF1 RN, RNU2AF1, U2AF35, U2AFBP ENSG00000160201 U2 small nuclear RNA auxiliary factor 1 21 43092956-43107587 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044833, HPA052083 Supported Enhanced Nucleoplasm Not detected Expressed in all thyroid gland: 70.1 Expressed in all +CRYAA CRYA1, HSPB4 ENSG00000160202 Crystallin alpha A 21 43169008-43172805 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037737, HPA038430 Supported Approved Nucleoplasm
Cytosol Not detected Tissue enriched 8 kidney: 12.3 liver: 1.5 Cell line enriched 95 Hep G2: 25.4 +HSF2BP ENSG00000160207 Heat shock transcription factor 2 binding protein 21 43529192-43659493 Predicted intracellular proteins Evidence at protein level HPA031724 Approved Nucleus
Cytosol Mixed Tissue enriched 9 testis: 40.8 cerebral cortex: 4.4 Cell line enhanced HBEC3-KT: 9.1 +RRP1B KIAA0179, Nnp1, PPP1R136, RRP1 ENSG00000160208 Ribosomal RNA processing 1B 21 43659548-43696079 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017893, HPA020324 Supported Enhanced Nucleoli Renal cancer:2.95e-9 (unfavourable) Expressed in all Expressed in all testis: 21.7 Expressed in all +PDXK C21orf124, C21orf97, FLJ21324, FLJ31940, MGC15873, PKH, PNK, PRED79 ENSG00000160209 Pyridoxal kinase 21 43719094-43762307 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030196, HPA030197, HPA030198, CAB033918 Approved Enhanced Nucleus Expressed in all Expressed in all cerebral cortex: 47.5 Expressed in all +G6PD G6PD1 ENSG00000160211 Glucose-6-phosphate dehydrogenase X 154531391-154547572 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000247, HPA000834 Enhanced Approved Vesicles
Microtubule organizing center
Cytosol Liver cancer:9.45e-13 (unfavourable) Expressed in all Expressed in all testis: 107.0 Expressed in all +CSTB CST6, EPM1, PME, STFB ENSG00000160213 Cystatin B 21 43772511-43776445 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA017380, CAB047320, HPA058557 Enhanced Supported Nucleoli
Cytosol Liver cancer:6.66e-5 (unfavourable), Renal cancer:2.10e-4 (unfavourable) Expressed in all Tissue enriched 8 esophagus: 1822.8 tonsil: 228.0 Expressed in all +RRP1 D21S2056E, NNP-1, Nop52, RRP1A ENSG00000160214 Ribosomal RNA processing 1 21 43789513-43805293 Predicted intracellular proteins Evidence at protein level HPA016818, HPA018166 Approved Enhanced Nucleoli Renal cancer:6.29e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 12.1 Expressed in all +AGPAT3 LPAAT-gamma ENSG00000160216 1-acylglycerol-3-phosphate O-acyltransferase 3 21 43865186-43986536 Enzymes, Predicted membrane proteins Evidence at protein level Renal cancer:2.29e-4 (favourable), Cervical cancer:8.31e-4 (unfavourable) Expressed in all Expressed in all small intestine: 57.5 Mixed +TRAPPC10 EHOC-1, TMEM1, TRS130 ENSG00000160218 Trafficking protein particle complex 10 21 44012319-44106552 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050423 Supported Expressed in all Expressed in all parathyroid gland: 14.4 Expressed in all +GAB3 ENSG00000160219 GRB2 associated binding protein 3 X 154675249-154751583 Predicted intracellular proteins Evidence at protein level HPA010090 Approved Renal cancer:5.07e-4 (unfavourable) Mixed Mixed spleen: 17.6 Cell line enhanced HEL: 21.1;HMC-1: 22.6 +C21orf33 D21S2048E, ES1, GT335, HES1, KNP-I, KNP-Ia, KNPH, KNPI ENSG00000160221 Chromosome 21 open reading frame 33 21 44133605-44145723 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018517 Supported Approved Centrosome
Mitochondria Mixed Expressed in all kidney: 35.4 Cell line enhanced Daudi: 101.9 +ICOSLG B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653 ENSG00000160223 Inducible T-cell costimulator ligand 21 44222991-44240966 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB026037, HPA029179 Uncertain Supported Plasma membrane
Cytoplasmic bodies Not detected Mixed bone marrow: 10.3 Mixed +AIRE APECED, APS1, PGA1 ENSG00000160224 Autoimmune regulator 21 44285838-44298648 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038267 Uncertain Tissue enriched Not detected lymph node: 0.3 Not detected +C21orf2 A2, LRRC76, YF5 ENSG00000160226 Chromosome 21 open reading frame 2 21 44328944-44339402 Predicted intracellular proteins Evidence at protein level HPA030284, CAB034126, CAB034128 Supported Approved Nucleoplasm Pancreatic cancer:1.32e-4 (favourable), Renal cancer:4.08e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 17.9 Mixed +ZNF66 FLJ16537, ZNF66P ENSG00000160229 Zinc finger protein 66 19 20776304-20807322 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at transcript level Mixed Tissue enhanced ovary: 9.5 thyroid gland: 4.2 Cell line enhanced RT4: 11.8 +LRRC3 C21orf102 ENSG00000160233 Leucine rich repeat containing 3 21 44455486-44462196 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA017975 Uncertain Mixed Mixed liver: 4.1 Cell line enhanced BEWO: 8.4;U-2 OS: 6.7 +ITGB2 CD18, LFA-1, MAC-1, MFI7 ENSG00000160255 Integrin subunit beta 2 21 44885953-44931989 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008877, HPA016894 Enhanced Approved Plasma membrane Expressed in all Expressed in all appendix: 239.2 Cell line enhanced EFO-21: 120.5;THP-1: 518.6;U-937: 447.2 +FAM207A C21orf70, PRED56 ENSG00000160256 Family with sequence similarity 207 member A 21 44940010-44976989 Predicted intracellular proteins Evidence at protein level CAB034178, HPA036354 Approved Approved Golgi apparatus
Vesicles Liver cancer:7.04e-4 (unfavourable), Renal cancer:7.80e-4 (unfavourable) Expressed in all Expressed in all testis: 20.8 Expressed in all +RALGDS RalGEF, RGDS, RGF ENSG00000160271 Ral guanine nucleotide dissociation stimulator 9 133097720-133149334 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA025961, CAB032582 Approved Approved Nucleus Cervical cancer:4.19e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 52.9 Expressed in all +FTCD ENSG00000160282 Formimidoyltransferase cyclodeaminase 21 46136262-46155567 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020073, HPA030928, HPA030929, HPA036114 Enhanced Approved Plasma membrane
Cytosol Pancreatic cancer:6.78e-5 (favourable), Liver cancer:1.70e-4 (favourable), Renal cancer:5.78e-4 (favourable) Tissue enriched Group enriched 18 kidney: 100.2;liver: 184.7 testis: 7.7 Cell line enriched 24 Hep G2: 62.7 +SPATC1L C21orf56 ENSG00000160284 Spermatogenesis and centriole associated 1 like 21 46161148-46184476 Predicted intracellular proteins Evidence at protein level HPA018979, HPA019165, HPA029394 Approved Approved Vesicles
Plasma membrane
Cytosol Pancreatic cancer:2.16e-4 (favourable) Expressed in all Tissue enhanced testis: 11.7 prostate: 7.4 Cell line enhanced K-562: 33.7 +LSS OSC ENSG00000160285 Lanosterol synthase 21 46188141-46228824 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA032060, HPA032062, CAB034116 Supported Approved Cytosol Urothelial cancer:3.07e-4 (unfavourable), Stomach cancer:6.80e-4 (unfavourable) Expressed in all Expressed in all prostate: 38.7 Expressed in all +VAV2 ENSG00000160293 Vav guanine nucleotide exchange factor 2 9 133761894-133992604 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003224 Uncertain Approved Vesicles Renal cancer:7.39e-7 (favourable), Thyroid cancer:4.33e-4 (unfavourable) Expressed in all Mixed adrenal gland: 32.2 Mixed +MCM3AP GANP, KIAA0572, Map80, SAC3 ENSG00000160294 Minichromosome maintenance complex component 3 associated protein 21 46235126-46286297 Predicted intracellular proteins, Transporters Evidence at protein level HPA021527, HPA032103 Approved Supported Nucleus
Nuclear membrane
Cytosol Pancreatic cancer:2.05e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 35.8 Expressed in all +C21orf58 ENSG00000160298 Chromosome 21 open reading frame 58 21 46300181-46323875 Predicted intracellular proteins Evidence at protein level HPA035110, HPA035111 Uncertain Supported Nucleoplasm
Nuclear bodies Pancreatic cancer:4.20e-4 (favourable), Head and neck cancer:7.00e-4 (favourable), Melanoma:7.48e-4 (unfavourable) Expressed in all Tissue enhanced fallopian tube: 42.4 testis: 9.0 Mixed +PCNT KEN, KIAA0402, PCN, PCNT2, PCNTB, SCKL4 ENSG00000160299 Pericentrin 21 46324122-46445769 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016820, HPA019887, HPA032101 Enhanced Enhanced Centrosome Expressed in all Mixed skeletal muscle: 24.3 Expressed in all +DIP2A C21orf106, Dip2, KIAA0184 ENSG00000160305 Disco interacting protein 2 homolog A 21 46458899-46569852 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052516 Uncertain Approved Nucleus Head and neck cancer:9.35e-5 (favourable) Expressed in all Expressed in all testis: 13.9 Expressed in all +S100B S100beta ENSG00000160307 S100 calcium binding protein B 21 46598962-46605208 Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Transporters Evidence at protein level CAB000073, HPA015768, CAB078196 Enhanced Approved Nucleus
Vesicles Group enriched Group enriched 8 adipose tissue: 208.2;cerebral cortex: 626.3 seminal vesicle: 49.5 Group enriched 6 SK-MEL-30: 519.7;WM-115: 1274.2 +PRMT2 HRMT1L1, MGC111373 ENSG00000160310 Protein arginine methyltransferase 2 21 46635167-46665124 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018976, HPA029591 Uncertain Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all ovary: 98.6 Expressed in all +CLDND2 MGC33839 ENSG00000160318 Claudin domain containing 2 19 51367098-51369003 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA056971 Uncertain Approved Nucleoplasm Mixed Tissue enhanced testis: 22.3 spleen: 6.2 Mixed +ZNF208 PMIDP, ZNF95 ENSG00000160321 Zinc finger protein 208 19 21932958-22010949 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enhanced Mixed testis: 16.5 Group enriched 10 NTERA-2: 33.9;U-266/84: 7.7 +ADAMTS13 C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP ENSG00000160323 ADAM metallopeptidase with thrombospondin type 1 motif 13 9 133414358-133459402 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042014, HPA042844 Uncertain Mixed Mixed liver: 6.2 Mixed +CACFD1 C9orf7, D9S2135, flower ENSG00000160325 Calcium channel flower domain containing 1 9 133459965-133470848 Predicted membrane proteins, Transporters Evidence at protein level HPA015280 Approved Nucleoplasm Renal cancer:2.83e-8 (favourable) Expressed in all Expressed in all thyroid gland: 16.6 Mixed +SLC2A6 GLUT6, GLUT9, HSA011372 ENSG00000160326 Solute carrier family 2 member 6 9 133471095-133479137 Predicted membrane proteins, Transporters Evidence at protein level HPA042272, CAB046014 Uncertain Renal cancer:1.02e-11 (unfavourable), Glioma:1.94e-4 (unfavourable), Liver cancer:8.82e-4 (unfavourable) Expressed in all Mixed appendix: 6.1 Cell line enhanced HMC-1: 57.7 +ZNF761 FLJ16231, FLJ35333, KIAA2033 ENSG00000160336 Zinc finger protein 761 19 53431993-53458261 Predicted intracellular proteins Evidence at transcript level Liver cancer:2.04e-4 (unfavourable) Expressed in all Expressed in all prostate: 91.8 Mixed +FCN2 EBP-37, FCNL, ficolin-2, P35 ENSG00000160339 Ficolin 2 9 134880812-134887520 Plasma proteins, Predicted secreted proteins Evidence at protein level Group enriched Tissue enriched 5 liver: 55.0 breast: 10.4 Not detected +C9orf116 MGC29761, PIERCE1, RbEST47 ENSG00000160345 Chromosome 9 open reading frame 116 9 135495181-135501734 Predicted intracellular proteins Evidence at protein level HPA021439, HPA065287 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:3.53e-5 (favourable) Expressed in all Group enriched 6 epididymis: 31.1;fallopian tube: 154.4;testis: 63.3 thyroid gland: 13.6 Cell line enhanced T-47d: 39.2;U-2197: 39.8 +LCN1 MGC71975, PMFA, TLC, TP, VEGP ENSG00000160349 Lipocalin 1 9 135521438-135526532 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Group enriched 11 fallopian tube: 3.1;seminal vesicle: 12.2 testis: 0.6 Not detected +ZNF714 ENSG00000160352 Zinc finger protein 714 19 21082159-21125270 Predicted intracellular proteins Evidence at protein level Ovarian cancer:4.27e-5 (favourable), Endometrial cancer:5.47e-4 (unfavourable) Mixed Tissue enhanced thyroid gland: 25.9 ovary: 21.9 Mixed +GPSM1 AGS3, DKFZP727I051 ENSG00000160360 G-protein signaling modulator 1 9 136327476-136359605 Predicted intracellular proteins Evidence at protein level HPA042199 Uncertain Supported Nucleoplasm
Golgi apparatus Renal cancer:3.30e-4 (unfavourable), Colorectal cancer:6.07e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 28.4 Cell line enhanced REH: 73.8 +C19orf47 FLJ36888 ENSG00000160392 Chromosome 19 open reading frame 47 19 40319536-40348527 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041843, HPA046309 Uncertain Enhanced Nucleoplasm Endometrial cancer:7.10e-5 (unfavourable), Liver cancer:1.41e-4 (unfavourable), Breast cancer:6.50e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 63.7 Expressed in all +HIPK4 FLJ32818 ENSG00000160396 Homeodomain interacting protein kinase 4 19 40379271-40390187 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027733 Uncertain Not detected Group enriched 29 cerebral cortex: 4.7;testis: 14.6 endometrium: 0.3 Not detected +CFAP157 C9orf117 ENSG00000160401 Cilia and flagella associated protein 157 9 127706989-127716002 Predicted intracellular proteins Evidence at protein level HPA021474, HPA021786 Enhanced Enhanced Plasma membrane
Cytosol Endometrial cancer:1.45e-4 (favourable) Mixed Tissue enriched 8 fallopian tube: 94.5 lung: 12.0 Cell line enhanced A549: 5.9;SCLC-21H: 5.2 +TOR2A FLJ14771, TORP1 ENSG00000160404 Torsin family 2 member A 9 127731524-127735317 Predicted secreted proteins Evidence at protein level HPA071229 Approved Stomach cancer:7.51e-4 (favourable) Expressed in all Mixed bone marrow: 16.5 Expressed in all +ST6GALNAC6 SIAT7F, ST6GALNACVI ENSG00000160408 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 9 127885321-127905408 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018890 Approved Approved Nucleus Expressed in all Expressed in all rectum: 154.1 Expressed in all +SHKBP1 PP203, Sb1 ENSG00000160410 SH3KBP1 binding protein 1 19 40576851-40591399 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041887 Uncertain Approved Cell Junctions Expressed in all Expressed in all spleen: 53.4 Expressed in all +RDH13 SDR7C3 ENSG00000160439 Retinol dehydrogenase 13 19 55039108-55071291 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042006 Approved Supported Mitochondria
Cytosol Renal cancer:2.09e-4 (favourable) Expressed in all Mixed placenta: 3.5 Mixed +ZER1 C9orf60, Hzyg, ZYG, ZYG11BL ENSG00000160445 Zyg-11 related cell cycle regulator 9 128729786-128772414 Predicted intracellular proteins Evidence at protein level HPA048464 Approved Cytosol Renal cancer:5.15e-11 (favourable), Cervical cancer:1.18e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 71.5 Expressed in all +ZDHHC12 FLJ14524, ZNF400 ENSG00000160446 Zinc finger DHHC-type containing 12 9 128720869-128724127 Enzymes, Predicted membrane proteins Evidence at transcript level HPA059339 Uncertain Approved Nucleoplasm Expressed in all Expressed in all small intestine: 35.8 Mixed +PKN3 PKNbeta, UTDP4-1 ENSG00000160447 Protein kinase N3 9 128702523-128720918 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045390, HPA058305 Uncertain Approved Vesicles Expressed in all Mixed adipose tissue: 7.6 Cell line enhanced HeLa: 45.8 +SPTBN4 KIAA1642, SPTBN3 ENSG00000160460 Spectrin beta, non-erythrocytic 4 19 40466241-40576464 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054481 Enhanced Approved Nucleus
Nucleoli Mixed Tissue enriched 6 cerebral cortex: 18.6 adrenal gland: 2.8 Cell line enhanced K-562: 1.6;Karpas-707: 1.8;SCLC-21H: 4.6;SH-SY5Y: 2.5 +BRSK1 KIAA1811 ENSG00000160469 BR serine/threonine kinase 1 19 55282072-55312533 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021212, HPA061719 Supported Supported Nucleoplasm Renal cancer:7.98e-6 (unfavourable), Pancreatic cancer:1.02e-4 (favourable) Expressed in all Tissue enriched 6 cerebral cortex: 137.8 parathyroid gland: 24.6 Cell line enhanced SCLC-21H: 65.8;SH-SY5Y: 53.1 +COX6B2 COXVIB2, CT59, FLJ32865 ENSG00000160471 Cytochrome c oxidase subunit 6B2 19 55349306-55354814 Predicted intracellular proteins, Transporters Evidence at protein level HPA035014 Approved Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:9.70e-5 (unfavourable) Mixed Tissue enriched 14 testis: 74.5 rectum: 5.2 Group enriched 6 CAPAN-2: 21.1;SCLC-21H: 11.9 +TMEM190 MDAC1 ENSG00000160472 Transmembrane protein 190 19 55376836-55378244 Predicted membrane proteins Evidence at protein level Group enriched Tissue enriched 9 fallopian tube: 231.3 testis: 26.4 Cell line enhanced Hep G2: 7.3;SCLC-21H: 6.1 +NLRP4 CLR19.5, CT58, FLJ32126, NALP4, PAN2, PYPAF4, RNH2 ENSG00000160505 NLR family pyrin domain containing 4 19 55836578-55881854 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enhanced testis: 12.8;tonsil: 4.6 lymph node: 1.9 Cell line enriched 6 Daudi: 58.8 +PLPP7 C9orf67, FLJ14662, MGC12921, NET39, PPAPDC3 ENSG00000160539 Phospholipid phosphatase 7 (inactive) 9 131289694-131309262 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA070252 Uncertain Approved Nucleus
Vesicles Mixed Group enriched 5 heart muscle: 32.6;skeletal muscle: 72.2 cerebral cortex: 10.1 Cell line enhanced AN3-CA: 10.2;ASC diff: 7.8;SCLC-21H: 13.4;SH-SY5Y: 9.1 +TAOK1 FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1 ENSG00000160551 TAO kinase 1 17 29390464-29551904 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007669 Approved Approved Vesicles Expressed in all Expressed in all parathyroid gland: 41.5 Expressed in all +MED27 CRSP34, CRSP8, MED3, TRAP37 ENSG00000160563 Mediator complex subunit 27 9 131860107-132079908 Predicted intracellular proteins Evidence at protein level HPA007002 Approved Supported Nucleus
Nucleoli
Cytosol Cervical cancer:1.59e-4 (favourable) Expressed in all Expressed in all testis: 29.2 Expressed in all +DEDD2 FLAME-3 ENSG00000160570 Death effector domain containing 2 19 42198598-42220140 Predicted intracellular proteins Evidence at protein level HPA043419 Approved Nucleoplasm Urothelial cancer:3.26e-6 (favourable) Expressed in all Mixed spleen: 11.8 Mixed +SIK3 FLJ12240, KIAA0999, L19, QSK ENSG00000160584 SIK family kinase 3 11 116843402-117098437 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045245, HPA048161 Enhanced Approved Nucleoplasm Renal cancer:1.12e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 42.9 Expressed in all +MPZL3 ENSG00000160588 Myelin protein zero like 3 11 118226690-118252350 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029116 Approved Golgi apparatus Thyroid cancer:3.64e-4 (favourable), Pancreatic cancer:4.98e-4 (unfavourable) Expressed in all Mixed skin: 25.8 Cell line enhanced CAPAN-2: 23.2;HMC-1: 25.7 +JAML AMICA, AMICA1, Gm638 ENSG00000160593 Junction adhesion molecule like 11 118193740-118225094 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA047919 Approved Head and neck cancer:3.11e-4 (favourable), Lung cancer:3.92e-4 (favourable) Mixed Tissue enhanced appendix: 82.3 spleen: 67.0 Cell line enhanced CACO-2: 4.8;HMC-1: 24.2 +NEK8 NPHP9 ENSG00000160602 NIMA related kinase 8 17 28725897-28743455 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA040661, HPA040679 Approved Lung cancer:4.52e-4 (favourable), Colorectal cancer:6.98e-4 (unfavourable) Expressed in all Mixed thyroid gland: 9.7 Mixed +TLCD1 ENSG00000160606 TLC domain containing 1 17 28724348-28727935 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042366 Enhanced Renal cancer:9.05e-5 (unfavourable), Liver cancer:3.28e-4 (unfavourable) Expressed in all Mixed fallopian tube: 23.4 Cell line enhanced SK-BR-3: 86.3 +PCSK7 LPC, PC7, PC8, SPC7 ENSG00000160613 Proprotein convertase subtilisin/kexin type 7 11 117204337-117232525 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043181, HPA052957 Uncertain Nucleus
Nuclear membrane
Nucleoli Expressed in all Expressed in all endometrium: 75.4 Expressed in all +SAFB HET, SAFB1 ENSG00000160633 Scaffold attachment factor B 19 5623035-5668478 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001969, HPA016832, HPA020076 Supported Enhanced Nucleoplasm Pancreatic cancer:9.75e-5 (favourable), Urothelial cancer:1.70e-4 (favourable) Expressed in all Expressed in all spleen: 53.9 Expressed in all +CD3G ENSG00000160654 CD3g molecule 11 118344344-118355161 CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017520, HPA038494 Enhanced Renal cancer:9.33e-5 (unfavourable), Cervical cancer:2.61e-4 (favourable), Head and neck cancer:3.00e-4 (favourable), Breast cancer:6.33e-4 (favourable) Mixed Tissue enhanced lymph node: 31.4;tonsil: 18.8 spleen: 16.1 Cell line enriched 69 MOLT-4: 160.9 +S100A1 S100-alpha, S100A ENSG00000160678 S100 calcium binding protein A1 1 153627926-153632039 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB002599, HPA006462 Enhanced Endometrial cancer:1.12e-4 (unfavourable), Renal cancer:3.08e-4 (unfavourable) Group enriched Group enriched 5 heart muscle: 1882.3;skeletal muscle: 995.9 thyroid gland: 267.2 Cell line enhanced EFO-21: 122.7;Hep G2: 207.0;SK-MEL-30: 802.9 +CHTOP C1orf77, DKFZP547E1010, FOP, SRAG ENSG00000160679 Chromatin target of PRMT1 1 153633982-153646306 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028647, HPA030540 Approved Enhanced Nuclear speckles Renal cancer:2.02e-4 (unfavourable), Urothelial cancer:2.69e-4 (favourable), Melanoma:4.08e-4 (unfavourable), Liver cancer:4.85e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 62.2 Expressed in all +CXCR5 BLR1, CD185, MDR15 ENSG00000160683 C-X-C motif chemokine receptor 5 11 118883766-118897799 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB026149, HPA042432 Enhanced Not detected Tissue enhanced appendix: 14.5;lymph node: 32.5;spleen: 21.0;tonsil: 14.3 bone marrow: 6.4 Group enriched 8 Daudi: 12.9;U-698: 43.3 +ZBTB7B c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B ENSG00000160685 Zinc finger and BTB domain containing 7B 1 155002630-155018522 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006811, HPA025820 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all skin: 89.4 Mixed +FLAD1 FAD1, PP591 ENSG00000160688 Flavin adenine dinucleotide synthetase 1 1 154983338-154993111 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028476, HPA028486, HPA028563 Approved Supported Plasma membrane
Cytosol Renal cancer:2.55e-6 (unfavourable), Liver cancer:3.04e-4 (unfavourable) Expressed in all Expressed in all skin: 28.5 Expressed in all +SHC1 p66, SHC, ShcA ENSG00000160691 SHC adaptor protein 1 1 154962298-154974395 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA001844, CAB005374, CAB016305 Supported Enhanced Cytosol Renal cancer:2.22e-16 (unfavourable), Lung cancer:1.92e-4 (unfavourable), Cervical cancer:6.74e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 162.2 Expressed in all +VPS11 PEP5, RNF108 ENSG00000160695 VPS11, CORVET/HOPS core subunit 11 119067692-119081978 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039020 Approved Approved Cytosol Renal cancer:1.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.5 Expressed in all +NLRX1 CLR11.3, NOD9 ENSG00000160703 NLR family member X1 11 119166568-119184016 Predicted intracellular proteins Evidence at protein level HPA061516 Supported Supported Plasma membrane
Cell Junctions
Mitochondria Renal cancer:2.59e-6 (favourable), Endometrial cancer:2.47e-5 (favourable) Expressed in all Expressed in all esophagus: 37.8 Mixed +ADAR ADAR1, G1P1, IFI4 ENSG00000160710 Adenosine deaminase, RNA specific 1 154582062-154627999 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003890, HPA051519, CAB056157 Enhanced Enhanced Nucleus
Nucleoli Renal cancer:7.30e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 121.4 Expressed in all +IL6R CD126 ENSG00000160712 Interleukin 6 receptor 1 154405193-154469450 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Pancreatic cancer:1.65e-4 (favourable) Expressed in all Mixed appendix: 33.4 Cell line enhanced THP-1: 147.4;U-266/84: 186.8 +UBE2Q1 NICE-5, PRO3094, UBE2Q ENSG00000160714 Ubiquitin conjugating enzyme E2 Q1 1 154548577-154559028 Enzymes, Predicted intracellular proteins Evidence at protein level HPA063368 Approved Approved Nucleoplasm
Centrosome Renal cancer:4.84e-7 (unfavourable), Thyroid cancer:1.86e-5 (favourable), Liver cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all testis: 57.0 Expressed in all +CHRNB2 ENSG00000160716 Cholinergic receptor nicotinic beta 2 subunit 1 154567781-154580026 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Tissue enhanced Tissue enriched 15 cerebral cortex: 21.2 adrenal gland: 1.4 Group enriched 7 SCLC-21H: 30.2;SH-SY5Y: 27.0 +CRTC2 TORC2 ENSG00000160741 CREB regulated transcription coactivator 2 1 153947669-153958625 Predicted intracellular proteins Evidence at protein level HPA028454, HPA028465 Supported Enhanced Nucleoplasm Renal cancer:1.35e-7 (unfavourable), Urothelial cancer:6.12e-5 (favourable), Colorectal cancer:5.75e-4 (unfavourable) Expressed in all Expressed in all spleen: 36.0 Expressed in all +ANO10 FLJ10375, MGC47890, SCAR10, TMEM16K ENSG00000160746 Anoctamin 10 3 43354859-43691594 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051569 Approved Renal cancer:6.41e-6 (favourable), Endometrial cancer:1.11e-4 (favourable), Liver cancer:3.19e-4 (unfavourable), Colorectal cancer:6.70e-4 (favourable) Expressed in all Expressed in all duodenum: 62.5 Mixed +FDPS ENSG00000160752 Farnesyl diphosphate synthase 1 155308748-155320666 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028200 Approved Approved Nucleoplasm
Cytosol Liver cancer:7.35e-4 (unfavourable) Expressed in all Expressed in all liver: 186.4 Expressed in all +RUSC1 NESCA ENSG00000160753 RUN and SH3 domain containing 1 1 155320896-155331114 Predicted intracellular proteins Evidence at protein level HPA028510, HPA029922, HPA029923 Approved Supported Cytosol Liver cancer:7.78e-6 (unfavourable), Renal cancer:9.24e-6 (unfavourable), Prostate cancer:2.65e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 38.5 Expressed in all +FAM189B C1orf2, cote1 ENSG00000160767 Family with sequence similarity 189 member B 1 155247205-155255483 Predicted membrane proteins Evidence at protein level HPA006659, HPA050674 Uncertain Supported Nucleoplasm Renal cancer:3.43e-7 (unfavourable), Endometrial cancer:9.59e-5 (unfavourable), Liver cancer:3.43e-4 (unfavourable), Cervical cancer:4.98e-4 (unfavourable) Expressed in all Mixed seminal vesicle: 6.8 Expressed in all +PAQR6 FLJ22672, PRdelta ENSG00000160781 Progestin and adipoQ receptor family member 6 1 156243321-156248117 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA073505 Approved Nucleus
Nucleoli Renal cancer:1.58e-8 (unfavourable), Colorectal cancer:1.60e-5 (unfavourable), Urothelial cancer:1.86e-4 (favourable), Prostate cancer:1.99e-4 (unfavourable) Tissue enriched Tissue enriched 9 cerebral cortex: 97.5 skin: 10.7 Cell line enhanced U-266/70: 19.6 +PMF1 ENSG00000160783 Polyamine modulated factor 1 1 156212993-156240042 Predicted intracellular proteins Evidence at protein level HPA034583, HPA071854 Approved Nucleoplasm
Vesicles Expressed in all Expressed in all thyroid gland: 68.6 Expressed in all +SLC25A44 FLJ90431, KIAA0446 ENSG00000160785 Solute carrier family 25 member 44 1 156193932-156212796 Predicted membrane proteins, Transporters Evidence at protein level HPA065411 Approved Nucleus
Mitochondria Pancreatic cancer:2.49e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 43.0 Expressed in all +LMNA CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1 ENSG00000160789 Lamin A/C 1 156082573-156140089 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004022, HPA006660 Supported Expressed in all Expressed in all gallbladder: 343.4 Expressed in all +CCR5 CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 ENSG00000160791 C-C motif chemokine receptor 5 (gene/pseudogene) 3 46370854-46376206 CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Endometrial cancer:7.42e-5 (favourable), Head and neck cancer:9.33e-5 (favourable) Expressed in all Mixed appendix: 20.4 Group enriched 17 Karpas-707: 4.9;U-266/84: 2.1 +NBEAL2 KIAA0540 ENSG00000160796 Neurobeachin like 2 3 46979683-47009703 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051969 Approved Head and neck cancer:4.60e-4 (favourable) Expressed in all Expressed in all bone marrow: 76.6 Cell line enhanced HEL: 69.8 +CCDC12 MGC23918 ENSG00000160799 Coiled-coil domain containing 12 3 46921726-46982010 Predicted intracellular proteins Evidence at protein level HPA056814, HPA060530 Approved Supported Nucleoplasm Renal cancer:1.15e-4 (favourable) Expressed in all Expressed in all adrenal gland: 58.1 Expressed in all +PTH1R PTHR, PTHR1 ENSG00000160801 Parathyroid hormone 1 receptor 3 46877746-46903799 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA007978 Approved Renal cancer:6.79e-6 (favourable) Tissue enhanced Tissue enhanced kidney: 158.9 adrenal gland: 36.7 Cell line enriched 8 RPTEC TERT1: 88.0 +UBQLN4 A1U, C1orf6, UBIN ENSG00000160803 Ubiquilin 4 1 156035301-156053794 Predicted intracellular proteins, Transporters Evidence at protein level HPA061797 Approved Supported Nucleus Expressed in all Expressed in all cerebral cortex: 41.1 Expressed in all +MYL3 CMH8, MLC1SB, MLC1V, VLC1 ENSG00000160808 Myosin light chain 3 3 46857872-46882169 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016564, CAB018662, HPA046859, HPA063034 Enhanced Approved Nucleoli
Mitochondria Renal cancer:1.22e-8 (favourable) Tissue enhanced Group enriched 11 heart muscle: 1578.0;skeletal muscle: 1730.1 esophagus: 157.4 Cell line enhanced CACO-2: 6.4;HSkMC: 5.6;RPTEC TERT1: 27.5 +PPP1R35 C7orf47, MGC22793 ENSG00000160813 Protein phosphatase 1 regulatory subunit 35 7 100435282-100436565 Predicted intracellular proteins Evidence at protein level HPA021604, HPA051607 Enhanced Approved Nucleoplasm Urothelial cancer:4.97e-4 (favourable) Expressed in all Tissue enhanced testis: 34.2 spleen: 17.9 Expressed in all +GPATCH4 DKFZP434F1735, FLJ20249, GPATC4 ENSG00000160818 G-patch domain containing 4 1 156594487-156601496 Predicted intracellular proteins Evidence at protein level HPA028323, HPA054319 Approved Supported Nucleus
Nucleoli Liver cancer:3.17e-5 (unfavourable), Renal cancer:3.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.5 Expressed in all +LRRC71 C1orf92, FLJ32884 ENSG00000160838 Leucine rich repeat containing 71 1 156920650-156933094 Predicted intracellular proteins Evidence at protein level Tissue enriched Group enriched 9 fallopian tube: 20.1;testis: 22.2 lung: 2.3 Cell line enhanced HBEC3-KT: 2.6;PC-3: 1.5;TIME: 1.2 +FCRL3 CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e ENSG00000160856 Fc receptor like 3 1 157674321-157700857 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA048022 Enhanced Mixed Group enriched 13 appendix: 18.1;lymph node: 55.9;spleen: 36.7;tonsil: 32.3 urinary bladder: 2.8 Cell line enriched 7 Daudi: 6.9 +AZGP1 ZA2G, ZAG ENSG00000160862 Alpha-2-glycoprotein 1, zinc-binding 7 99966720-99976157 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012582, CAB016087, CAB032276 Enhanced Renal cancer:1.53e-4 (favourable), Liver cancer:2.90e-4 (favourable) Group enriched Tissue enhanced breast: 1201.5;liver: 1272.1;prostate: 1490.2;salivary gland: 1423.5 kidney: 294.4 Cell line enhanced Hep G2: 33.7;RPMI-8226: 79.5;T-47d: 35.0 +FGFR4 CD334, JTK2 ENSG00000160867 Fibroblast growth factor receptor 4 5 177086886-177098144 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB005196, HPA027273, HPA027369, HPA028251 Approved Mixed Tissue enhanced lung: 38.9 duodenum: 21.4 Cell line enhanced CACO-2: 142.3;Hep G2: 118.3;RH-30: 260.0 +CYP3A4 CYP3A3 ENSG00000160868 Cytochrome P450 family 3 subfamily A member 4 7 99756960-99784265 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB033671, HPA072245 Enhanced Uncertain Cytosol Tissue enriched Group enriched 199 duodenum: 826.8;liver: 2451.8;small intestine: 971.1 adrenal gland: 7.1 Cell line enhanced BEWO: 1.8;NB-4: 1.3;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.4 +CYP3A7 CP37, P450-HFLA ENSG00000160870 Cytochrome P450 family 3 subfamily A member 7 7 99705037-99735196 Enzymes, Predicted membrane proteins Evidence at protein level HPA072245 Uncertain Cytosol Tissue enriched Tissue enriched 15 liver: 143.3 kidney: 9.8 Cell line enhanced Hep G2: 1.6;HHSteC: 1.0 +NACC1 BEND8, BTBD14B, BTBD30, NAC-1, NAC1 ENSG00000160877 Nucleus accumbens associated 1 19 13118103-13141141 Predicted intracellular proteins Evidence at protein level HPA021238, HPA062245, CAB069927 Supported Enhanced Nucleoplasm Expressed in all Expressed in all cerebral cortex: 37.1 Expressed in all +CYP11B1 CPN1, CYP11B, FHI, P450C11 ENSG00000160882 Cytochrome P450 family 11 subfamily B member 1 8 142872356-142879846 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA049171, HPA056348, HPA057752 Supported Not detected Tissue enriched 916 adrenal gland: 1871.2 testis: 2.0 Not detected +HK3 ENSG00000160883 Hexokinase 3 5 176880869-176899332 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056743 Enhanced Renal cancer:3.84e-8 (unfavourable) Mixed Tissue enhanced bone marrow: 87.9 spleen: 27.9 Cell line enhanced SCLC-21H: 5.3;THP-1: 2.5;U-937: 16.3 +LY6K CT97, FLJ35226, HSJ001348 ENSG00000160886 Lymphocyte antigen 6 family member K 8 142700111-142705127 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017770, CAB075742, CAB075743 Enhanced Supported Nucleoplasm
Plasma membrane Lung cancer:9.17e-5 (unfavourable) Mixed Tissue enhanced testis: 29.0 adipose tissue: 5.9 Cell line enhanced A-431: 108.7;BJ: 111.4;HeLa: 95.9;SiHa: 218.6;U-2197: 254.2 +IER2 ETR101 ENSG00000160888 Immediate early response 2 19 13150415-13154908 Predicted intracellular proteins Evidence at protein level HPA055387, HPA060574 Enhanced Nucleoplasm Expressed in all Expressed in all fallopian tube: 161.2 Expressed in all +ZNF394 FLJ12298, ZKSCAN14, ZSCAN46 ENSG00000160908 Zinc finger protein 394 7 99486519-99500324 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051421, HPA054639 Uncertain Approved Nucleoplasm
Cytosol Urothelial cancer:1.09e-4 (favourable), Lung cancer:2.11e-4 (favourable), Breast cancer:3.56e-4 (favourable) Expressed in all Expressed in all bone marrow: 62.0 Expressed in all +CPSF4 CPSF30, NAR ENSG00000160917 Cleavage and polyadenylation specific factor 4 7 99438922-99457371 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049094, HPA066470 Uncertain Supported Nucleoplasm Renal cancer:1.68e-4 (unfavourable), Liver cancer:5.87e-4 (unfavourable) Expressed in all Expressed in all testis: 43.8 Expressed in all +LY6E RIG-E, SCA-2, TSA-1 ENSG00000160932 Lymphocyte antigen 6 family member E 8 143017982-143023832 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Renal cancer:6.74e-8 (unfavourable) Expressed in all Expressed in all lung: 109.0 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 564.1;MCF7: 492.5 +VPS28 ENSG00000160948 VPS28, ESCRT-I subunit 8 144423601-144428563 Predicted intracellular proteins Evidence at protein level HPA024688, HPA024745 Enhanced Endometrial cancer:9.93e-4 (favourable) Expressed in all Expressed in all fallopian tube: 237.0 Expressed in all +TONSL IKBR, NFKBIL2 ENSG00000160949 Tonsoku-like, DNA repair protein 8 144428775-144444444 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024679, HPA046494 Uncertain Enhanced Nucleoplasm
Nuclear bodies Renal cancer:2.62e-7 (unfavourable), Liver cancer:2.84e-4 (unfavourable) Expressed in all Mixed bone marrow: 5.4 Mixed +PTGER1 EP1 ENSG00000160951 Prostaglandin E receptor 1 19 14472466-14475362 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level Tissue enhanced Tissue enhanced kidney: 2.9;spleen: 2.5 lung: 0.7 Cell line enhanced HEL: 2.2;PC-3: 2.9;SH-SY5Y: 1.9 +MUM1 EXPAND1, MUM-1 ENSG00000160953 Melanoma associated antigen (mutated) 1 19 1354711-1378431 Predicted intracellular proteins Evidence at protein level HPA048063 Uncertain Approved Nucleus
Cytosol Pancreatic cancer:2.25e-6 (favourable), Endometrial cancer:4.82e-4 (favourable) Expressed in all Expressed in all testis: 51.0 Expressed in all +RECQL4 RecQ4 ENSG00000160957 RecQ like helicase 4 8 144511288-144517845 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB017800, HPA025821 Supported Enhanced Nucleus Liver cancer:1.91e-4 (unfavourable) Expressed in all Mixed testis: 17.3 Mixed +LRRC14 KIAA0014, LRRC14A ENSG00000160959 Leucine rich repeat containing 14 8 144517992-144525178 Predicted intracellular proteins Evidence at protein level HPA021047 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:1.78e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.6 Expressed in all +ZNF333 KIAA1806 ENSG00000160961 Zinc finger protein 333 19 14689801-14733746 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA043973, HPA054680 Uncertain Approved Nucleoplasm Mixed Mixed endometrium: 11.1 Mixed +COL26A1 EMI6, EMID2, Emu2 ENSG00000160963 Collagen type XXVI alpha 1 chain 7 101362820-101559024 Predicted secreted proteins Evidence at protein level HPA027059 Approved Approved Vesicles Liver cancer:2.32e-5 (favourable) Group enriched Tissue enhanced cerebral cortex: 10.2;parathyroid gland: 5.4 prostate: 3.1 Cell line enhanced AF22: 29.3;BEWO: 22.8;HAP1: 10.9;NTERA-2: 25.1 +PPP1R16A MGC14333, MYPT3 ENSG00000160972 Protein phosphatase 1 regulatory subunit 16A 8 144477969-144502121 Predicted intracellular proteins Evidence at protein level HPA023755 Uncertain Approved Plasma membrane Expressed in all Mixed duodenum: 27.2 Mixed +FOXH1 FAST1 ENSG00000160973 Forkhead box H1 8 144473412-144476335 Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enriched Not detected small intestine: 0.9 Cell line enriched 21 NTERA-2: 20.6 +ORAI2 C7orf19, CBCIP2, FLJ12474, FLJ14733, H_NH0514P08.8, TMEM142B ENSG00000160991 ORAI calcium release-activated calcium modulator 2 7 102433106-102456821 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055137, HPA065937 Uncertain Approved Nucleus Pancreatic cancer:8.49e-5 (favourable), Thyroid cancer:6.65e-4 (favourable) Expressed in all Mixed appendix: 41.9 Expressed in all +ALKBH4 FLJ20013 ENSG00000160993 AlkB homolog 4, lysine demethylase 7 102456238-102464876 Predicted intracellular proteins Evidence at protein level HPA051422 Approved Renal cancer:3.09e-4 (favourable) Expressed in all Mixed cerebral cortex: 10.0 Expressed in all +CCDC105 FLJ40365 ENSG00000160994 Coiled-coil domain containing 105 19 15010744-15023269 Predicted intracellular proteins Evidence at protein level HPA058585 Approved Not detected Tissue enriched 104 testis: 11.7 skin: 0.1 Not detected +SH2B2 APS ENSG00000160999 SH2B adaptor protein 2 7 102285091-102321711 Predicted intracellular proteins Evidence at protein level HPA051131 Uncertain Enhanced Cytosol Renal cancer:6.99e-7 (unfavourable) Expressed in all Mixed skeletal muscle: 12.9 Cell line enhanced Daudi: 46.0;Karpas-707: 43.6;U-266/70: 42.7;U-266/84: 73.5;U-698: 59.4 +MRNIP C5orf45, DKFZp686L2452, LOC51149, MGC65027, MGC78537 ENSG00000161010 MRN complex interacting protein 5 179835133-179862173 Predicted intracellular proteins Evidence at protein level HPA043975 Uncertain Approved Plasma membrane
Cytosol Renal cancer:2.64e-5 (unfavourable) Expressed in all Mixed fallopian tube: 13.8 Mixed +SQSTM1 A170, OSIL, p60, p62, p62B, PDB3 ENSG00000161011 Sequestosome 1 5 179806398-179838078 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004587, HPA064165, HPA068843 Supported Enhanced Vesicles
Cytosol Liver cancer:2.31e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 371.5 Expressed in all +MGAT4B GnT-Ivb ENSG00000161013 Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 5 179797597-179806952 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA052134 Uncertain Glioma:8.53e-5 (unfavourable), Renal cancer:5.78e-4 (favourable) Expressed in all Expressed in all small intestine: 153.7 Expressed in all +RPL8 L8 ENSG00000161016 Ribosomal protein L8 8 144789765-144792587 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA045095, HPA050165 Enhanced Enhanced Nucleoli
Endoplasmic reticulum
Cytosol Liver cancer:7.22e-4 (unfavourable) Expressed in all Expressed in all ovary: 954.7 Expressed in all +MAML1 KIAA0200, Mam-1 ENSG00000161021 Mastermind like transcriptional coactivator 1 5 179732850-179796511 Predicted intracellular proteins Evidence at protein level HPA037687, HPA057531 Approved Enhanced Nucleoplasm Renal cancer:1.84e-5 (unfavourable), Melanoma:9.70e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 15.3 small intestine: 8.5 Cell line enhanced SK-MEL-30: 15.6 +PGLYRP2 PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like ENSG00000161031 Peptidoglycan recognition protein 2 19 15468645-15498956 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB033468, HPA043568, HPA046311, HPA075237 Approved Approved Cell Junctions Tissue enriched Tissue enriched 17 liver: 133.2 testis: 7.8 Group enriched 8 MCF7: 5.7;T-47d: 6.8 +LRWD1 CENP-33, DKFZp434K1815, ORCA ENSG00000161036 Leucine rich repeats and WD repeat domain containing 1 7 102464929-102473168 Predicted intracellular proteins Evidence at protein level HPA021320 Enhanced Supported Nucleus
Nucleoli
Vesicles Pancreatic cancer:8.71e-5 (favourable), Renal cancer:1.25e-4 (unfavourable) Expressed in all Tissue enriched 11 testis: 209.0 fallopian tube: 18.8 Expressed in all +FBXL13 DRC6, Fbl13, MGC21636 ENSG00000161040 F-box and leucine rich repeat protein 13 7 102813230-103074843 Predicted intracellular proteins Evidence at protein level HPA057232 Uncertain Mixed Group enriched 5 fallopian tube: 7.9;testis: 37.4 stomach: 4.5 Cell line enhanced HUVEC TERT2: 11.6;U-266/84: 12.5;U-87 MG: 9.3;U-937: 9.5 +NAPEPLD C7orf18, FMP30, NAPE-PLD ENSG00000161048 N-acyl phosphatidylethanolamine phospholipase D 7 103099776-103149560 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019832, HPA024338 Approved Enhanced Cytosol Renal cancer:7.32e-6 (favourable) Expressed in all Mixed cerebral cortex: 11.2 Mixed +SCGB3A1 HIN-1, HIN1, LU105, PnSP-2, UGRP2 ENSG00000161055 Secretoglobin family 3A member 1 5 180590103-180591540 Plasma proteins, Predicted secreted proteins Evidence at protein level Group enriched Group enriched 6 breast: 125.3;cervix, uterine: 345.8;lung: 301.1;salivary gland: 193.1 stomach: 40.9 Cell line enhanced NB-4: 1.3 +PSMC2 MSS1, Nbla10058, S7 ENSG00000161057 Proteasome 26S subunit, ATPase 2 7 103344254-103369395 Predicted intracellular proteins Evidence at protein level HPA019238, HPA049621 Supported Supported Cytosol
Cytoplasmic bodies Expressed in all Expressed in all testis: 105.0 Expressed in all +CELF5 BRUNOL5 ENSG00000161082 CUGBP Elav-like family member 5 19 3224703-3297076 Predicted intracellular proteins Evidence at protein level HPA042012, HPA060336 Enhanced Tissue enhanced Tissue enriched 7 cerebral cortex: 38.1 ovary: 5.1 Cell line enhanced NTERA-2: 3.5;REH: 4.0;SCLC-21H: 5.2;SH-SY5Y: 2.8 +MFSD12 C19orf28, MGC20700, PP3501 ENSG00000161091 Major facilitator superfamily domain containing 12 19 3538261-3574290 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042149, HPA043088 Uncertain Approved Nucleoplasm
Mitochondria Endometrial cancer:5.66e-6 (favourable), Lung cancer:2.34e-4 (unfavourable), Liver cancer:6.61e-4 (unfavourable), Stomach cancer:7.70e-4 (favourable) Tissue enriched Expressed in all skin: 64.2 Expressed in all +USP41 ENSG00000161133 Ubiquitin specific peptidase 41 22 20350578-20390758 Enzymes, Predicted intracellular proteins Evidence at transcript level Not detected Not detected cerebral cortex: 0.3 Cell line enhanced RH-30: 1.2;SCLC-21H: 1.8 +YDJC ENSG00000161179 YdjC homolog (bacterial) 22 21628089-21630064 Predicted intracellular proteins Evidence at protein level HPA061005 Approved Nucleoplasm Urothelial cancer:8.98e-5 (favourable), Liver cancer:9.84e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 2.8 Cell line enhanced K-562: 71.0 +CCDC116 FLJ36046 ENSG00000161180 Coiled-coil domain containing 116 22 21632716-21637327 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 29 testis: 23.1 placenta: 0.7 Cell line enhanced HMC-1: 2.7 +DVL3 KIAA0208 ENSG00000161202 Dishevelled segment polarity protein 3 3 184155388-184173610 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB046486, HPA058265 Approved Approved Intermediate filaments
Midbody ring
Centrosome Renal cancer:1.53e-8 (unfavourable), Prostate cancer:4.77e-5 (unfavourable), Colorectal cancer:1.90e-4 (unfavourable), Liver cancer:8.41e-4 (unfavourable) Expressed in all Expressed in all placenta: 55.3 Expressed in all +AP2M1 AP50, CLAPM1, mu2 ENSG00000161203 Adaptor related protein complex 2 mu 1 subunit 3 184174689-184184091 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036849, HPA069870 Uncertain Supported Plasma membrane Renal cancer:7.45e-6 (unfavourable), Liver cancer:9.12e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 557.6 Expressed in all +ABCF3 EST201864 ENSG00000161204 ATP binding cassette subfamily F member 3 3 184186023-184194012 Predicted intracellular proteins Evidence at protein level HPA036332 Approved Approved Nucleoli
Cytosol Liver cancer:4.16e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 76.2 Expressed in all +PCYT1A CT, CTPCT, PCYT1 ENSG00000161217 Phosphate cytidylyltransferase 1, choline, alpha 3 196214222-196287957 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035428 Approved Approved Nucleus Liver cancer:8.65e-5 (unfavourable) Expressed in all Expressed in all duodenum: 66.9 Expressed in all +FBXO27 Fbg5, Fbx27 ENSG00000161243 F-box protein 27 19 38990714-39032785 Predicted intracellular proteins Evidence at protein level HPA046800, HPA062242 Approved Approved Nucleoplasm Endometrial cancer:3.53e-5 (unfavourable), Breast cancer:2.15e-4 (favourable), Glioma:7.83e-4 (unfavourable) Mixed Tissue enhanced skin: 22.7 esophagus: 8.4 Cell line enhanced RT4: 14.1 +DMKN ZD52F10 ENSG00000161249 Dermokine 19 35497220-35513658 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029406 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:5.37e-6 (favourable) Mixed Tissue enriched 15 skin: 3991.5 breast: 259.8 Cell line enhanced CACO-2: 150.9;HBEC3-KT: 169.4;RPTEC TERT1: 173.1 +U2AF1L4 MGC33901, U2AF1L3, U2af26 ENSG00000161265 U2 small nuclear RNA auxiliary factor 1 like 4 19 35742464-35745445 Predicted intracellular proteins Evidence at protein level HPA052083, HPA061644 Supported Approved Nucleoplasm Head and neck cancer:2.58e-5 (favourable), Pancreatic cancer:8.58e-5 (favourable), Renal cancer:9.73e-5 (unfavourable), Breast cancer:2.44e-4 (favourable), Urothelial cancer:7.05e-4 (favourable) Expressed in all Mixed testis: 7.7 Mixed +BDH1 BDH, SDR9C1 ENSG00000161267 3-hydroxybutyrate dehydrogenase 1 3 197509783-197573323 Candidate cardiovascular disease genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA030947, HPA058709 Enhanced Enhanced Mitochondria Renal cancer:7.12e-8 (favourable), Liver cancer:9.86e-7 (favourable), Cervical cancer:1.09e-4 (favourable) Expressed in all Tissue enriched 6 liver: 170.2 colon: 27.0 Cell line enhanced U-937: 60.1 +NPHS1 CNF, NPHN ENSG00000161270 NPHS1, nephrin 19 35825964-35869287 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB035555 Enhanced Mixed Tissue enhanced kidney: 17.7;lymph node: 5.4;pancreas: 5.5 tonsil: 2.3 Cell line enhanced HMC-1: 1.1 +THAP8 FLJ32891 ENSG00000161277 THAP domain containing 8 19 36034985-36054762 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA064056, HPA070139 Enhanced Nucleoplasm Liver cancer:1.32e-4 (unfavourable), Pancreatic cancer:3.19e-4 (favourable) Expressed in all Mixed testis: 9.0 Mixed +COX7A1 COX7A, COX7AH ENSG00000161281 Cytochrome c oxidase subunit 7A1 19 36150922-36152869 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Expressed in all Group enriched 6 heart muscle: 357.0;skeletal muscle: 1077.7 adipose tissue: 117.8 Cell line enhanced ASC diff: 34.1;ASC TERT1: 25.4;BJ: 29.4;BJ hTERT+: 23.3;fHDF/TERT166: 41.5;HHSteC: 27.7;HSkMC: 24.9 +ZNF382 FLJ14686, KS1 ENSG00000161298 Zinc finger protein 382 19 36604817-36634113 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049259 Approved Approved Nuclear speckles Mixed Mixed cerebral cortex: 10.9 Mixed +LRRC56 DKFZp761L1518, FLJ00101 ENSG00000161328 Leucine rich repeat containing 56 11 537527-554916 Predicted intracellular proteins Evidence at transcript level HPA038728 Uncertain Lung cancer:6.19e-4 (favourable), Pancreatic cancer:6.32e-4 (favourable), Endometrial cancer:7.39e-4 (favourable) Expressed in all Tissue enhanced testis: 3.9 epididymis,fallopian tube: 1.5 Cell line enhanced AN3-CA: 1.7;Karpas-707: 1.8;T-47d: 1.8 +PLXDC1 TEM3, TEM7 ENSG00000161381 Plexin domain containing 1 17 39063303-39154394 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012805 Approved Renal cancer:9.15e-8 (unfavourable) Expressed in all Mixed gallbladder: 22.8 Cell line enhanced BJ hTERT+: 7.5;U-87 MG: 5.7 +PGAP3 CAB2, MGC9753, PER1, PERLD1, PP1498 ENSG00000161395 Post-GPI attachment to proteins 3 17 39671122-39696797 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA016591 Approved Approved Plasma membrane
Cytosol Renal cancer:3.89e-4 (favourable), Liver cancer:3.94e-4 (favourable), Ovarian cancer:6.82e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 35.6 Cell line enhanced SK-BR-3: 99.2 +IKZF3 Aiolos, ZNFN1A3 ENSG00000161405 IKAROS family zinc finger 3 17 39757715-39864188 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017105, HPA024377 Enhanced Uncertain Plasma membrane
Cytosol Cervical cancer:6.85e-6 (favourable), Head and neck cancer:4.16e-4 (favourable), Melanoma:5.42e-4 (favourable), Renal cancer:7.38e-4 (unfavourable) Mixed Tissue enhanced lymph node: 44.7;spleen: 31.7;tonsil: 39.2 appendix: 25.5 Cell line enhanced Daudi: 50.3;Karpas-707: 25.9;U-266/70: 32.8;U-266/84: 35.9;U-698: 78.2 +GRIN2C GluN2C, NMDAR2C ENSG00000161509 Glutamate ionotropic receptor NMDA type subunit 2C 17 74842023-74861504 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 9.5;thyroid gland: 14.1 heart muscle: 6.1 Cell line enhanced BEWO: 6.1;SCLC-21H: 3.3 +FDXR ADXR ENSG00000161513 Ferredoxin reductase 17 74862497-74873031 Enzymes, Predicted intracellular proteins Evidence at protein level CAB008597, CAB009818, HPA044393, HPA053673 Enhanced Enhanced Mitochondria Endometrial cancer:2.38e-4 (favourable) Expressed in all Tissue enriched 6 adrenal gland: 232.0 testis: 39.1 Expressed in all +SAP30BP HCNGP, HTRG, HTRP ENSG00000161526 SAP30 binding protein 17 75667116-75708062 Predicted intracellular proteins Evidence at protein level HPA042382, HPA052943 Supported Enhanced Nucleoplasm Liver cancer:4.71e-5 (unfavourable), Renal cancer:1.98e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.5 Expressed in all +ACOX1 PALMCOX ENSG00000161533 Acyl-CoA oxidase 1 17 75941507-75979363 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB021094, HPA021192, HPA021195, HPA028759 Approved Enhanced Nucleus
Vesicles Renal cancer:5.25e-7 (favourable) Expressed in all Expressed in all liver: 98.4 Expressed in all +PRPSAP1 PAP39 ENSG00000161542 Phosphoribosyl pyrophosphate synthetase associated protein 1 17 76309486-76384521 Predicted intracellular proteins Evidence at protein level HPA062396 Approved Cytosol Colorectal cancer:1.39e-5 (favourable) Expressed in all Expressed in all thyroid gland: 82.4 Expressed in all +CYGB HGB, STAP ENSG00000161544 Cytoglobin 17 76527356-76551175 Predicted intracellular proteins, Transporters Evidence at protein level HPA017757, HPA061642 Approved Approved Enhanced Nuclear speckles Endometrial cancer:2.55e-5 (favourable), Glioma:1.63e-4 (unfavourable), Renal cancer:2.13e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 46.4 Cell line enhanced ASC diff: 50.4;Hep G2: 40.6;HHSteC: 93.4;HSkMC: 66.1;SH-SY5Y: 131.4 +SRSF2 PR264, SC-35, SC35, SFRS2, SFRS2A ENSG00000161547 Serine and arginine rich splicing factor 2 17 76734115-76737374 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049905 Supported Approved Nucleus
Cytosol Liver cancer:3.53e-8 (unfavourable), Renal cancer:1.05e-7 (unfavourable), Endometrial cancer:8.73e-4 (unfavourable), Urothelial cancer:9.87e-4 (favourable) Expressed in all Expressed in all lymph node: 127.2 Expressed in all +ZNF577 MGC4400 ENSG00000161551 Zinc finger protein 577 19 51804816-51890950 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041499, HPA046761 Uncertain Supported Nucleus
Nucleoli Urothelial cancer:2.03e-4 (favourable) Mixed Mixed ovary: 28.9 Mixed +TMEM143 FLJ10922 ENSG00000161558 Transmembrane protein 143 19 48332356-48364237 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014476 Uncertain Approved Nucleoli fibrillar center Renal cancer:1.53e-7 (favourable) Expressed in all Tissue enhanced skeletal muscle: 32.5 heart muscle: 15.5 Expressed in all +KLHL10 FLJ32662 ENSG00000161594 Kelch like family member 10 17 41835685-41848384 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA067538 Enhanced Not detected Tissue enriched 48 testis: 90.0 epididymis: 1.8 Not detected +CCDC155 FLJ32658, KASH5 ENSG00000161609 Coiled-coil domain containing 155 19 49388218-49417994 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019937, HPA019940 Enhanced Tissue enhanced Tissue enriched 135 testis: 56.9 pancreas: 0.4 Cell line enhanced SCLC-21H: 1.5;U-266/70: 2.7 +HCRT OX, PPOX ENSG00000161610 Hypocretin neuropeptide precursor 17 42184060-42185452 Disease related genes, Predicted secreted proteins Evidence at protein level CAB004758 Uncertain Tissue enhanced Not detected adipose tissue,appendix,cerebral cortex,duodenum: 0.1 Not detected +ALDH16A1 MGC10204 ENSG00000161618 Aldehyde dehydrogenase 16 family member A1 19 49453169-49471048 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA059488 Approved Supported Mitochondria Expressed in all Expressed in all spleen: 17.6 Mixed +DCD AIDD, DCD-1, DSEP, HCAP, PIF ENSG00000161634 Dermcidin 12 54644591-54648493 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA063967 Supported Tissue enriched Tissue enriched 96 breast: 336.4 skeletal muscle: 3.5 Not detected +ITGA5 CD49e, FNRA ENSG00000161638 Integrin subunit alpha 5 12 54395261-54419460 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA002642, CAB009008 Enhanced Renal cancer:1.32e-8 (unfavourable), Cervical cancer:4.07e-6 (unfavourable), Liver cancer:2.23e-5 (unfavourable), Lung cancer:2.44e-4 (unfavourable), Head and neck cancer:2.91e-4 (unfavourable), Colorectal cancer:8.43e-4 (unfavourable), Thyroid cancer:8.89e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 489.0 Cell line enhanced HUVEC TERT2: 1106.4;TIME: 1039.6;U-87 MG: 602.5 +SIGLEC11 ENSG00000161640 Sialic acid binding Ig like lectin 11 19 49948985-49961172 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA060278 Approved Mixed Group enriched 7 ovary: 80.0;spleen: 31.7 adrenal gland: 8.1 Cell line enriched 15 HEL: 9.4 +ZNF385A DKFZp586G1122, Hzf, ZFP385, ZNF385 ENSG00000161642 Zinc finger protein 385A 12 54369133-54391298 Predicted intracellular proteins Evidence at protein level HPA039799 Supported Nucleus
Cytosol Renal cancer:9.75e-5 (unfavourable), Colorectal cancer:5.20e-4 (unfavourable) Expressed in all Tissue enhanced skin: 170.0 cerebral cortex: 66.1 Cell line enhanced HEL: 98.3 +MPP3 DLG3 ENSG00000161647 Membrane palmitoylated protein 3 17 43800799-43833170 Predicted intracellular proteins Evidence at protein level HPA021818, HPA024742 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Mixed cerebral cortex: 2.9 Cell line enhanced SCLC-21H: 11.2 +CD300LG CLM9, Trem4 ENSG00000161649 CD300 molecule like family member g 17 43847148-43863629 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Mixed Group enriched 5 adipose tissue: 143.0;placenta: 86.4;testis: 33.9 lung: 17.3 Not detected +IZUMO2 C19orf41, MGC33947, SCRL ENSG00000161652 IZUMO family member 2 19 50152548-50163195 Predicted membrane proteins, Transporters Evidence at transcript level HPA042143 Uncertain Not detected Tissue enriched 250 testis: 56.1 prostate,skin,thyroid gland: 0.2 Not detected +NAGS AGAS, ARGA, NAT7 ENSG00000161653 N-acetylglutamate synthase 17 44004546-44009063 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027300 Supported Mitochondria Expressed in all Tissue enhanced duodenum: 14.8;small intestine: 13.6 liver: 5.0 Cell line enhanced HHSteC: 4.0;TIME: 5.0;U-87 MG: 8.7 +LSM12 FLJ30656 ENSG00000161654 LSM12 homolog 17 44034635-44067619 Predicted intracellular proteins Evidence at protein level HPA051934 Approved Approved Cytosol Renal cancer:1.18e-7 (unfavourable), Pancreatic cancer:7.49e-5 (unfavourable), Liver cancer:1.05e-4 (unfavourable) Expressed in all Expressed in all testis: 49.1 Expressed in all +ASB16 FLJ30165 ENSG00000161664 Ankyrin repeat and SOCS box containing 16 17 44170447-44179083 Predicted intracellular proteins Evidence at protein level HPA066834 Approved Approved Focal adhesion sites Mixed Tissue enriched 5 skeletal muscle: 23.2 spleen: 4.2 Mixed +EMC10 C19orf63, HSM1, HSS1, INM02 ENSG00000161671 ER membrane protein complex subunit 10 19 50476400-50490870 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA053905 Uncertain Renal cancer:6.64e-6 (favourable), Pancreatic cancer:4.39e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 63.8 Cell line enhanced HEK 293: 176.7 +JOSD2 SBBI54 ENSG00000161677 Josephin domain containing 2 19 50505998-50511353 Enzymes, Predicted intracellular proteins Evidence at protein level Liver cancer:6.04e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 16.8 Mixed +SHANK1 SPANK-1, SSTRIP, synamon ENSG00000161681 SH3 and multiple ankyrin repeat domains 1 19 50661827-50719450 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA032129, HPA032130 Uncertain Supported Plasma membrane Tissue enhanced Tissue enriched 24 cerebral cortex: 35.8 adrenal gland: 1.5 Cell line enhanced REH: 4.6;U-138 MG: 2.6;U-2 OS: 7.1 +FAM171A2 MGC34829 ENSG00000161682 Family with sequence similarity 171 member A2 17 44353215-44363875 Predicted membrane proteins Evidence at protein level HPA019770 Uncertain Mixed Tissue enhanced cerebral cortex: 13.3 epididymis: 3.3 Cell line enhanced REH: 20.9;SCLC-21H: 18.5 +DBF4B ASKL1, chifb, DRF1, FLJ13087, ZDBF1B ENSG00000161692 DBF4 zinc finger B 17 44708608-44752264 Predicted intracellular proteins Evidence at protein level HPA048465 Uncertain Supported Nucleus Expressed in all Mixed testis: 5.6 Mixed +PLCD3 ENSG00000161714 Phospholipase C delta 3 17 45108967-45133354 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025711, HPA053665 Approved Approved Plasma membrane Lung cancer:2.89e-6 (unfavourable), Thyroid cancer:4.28e-4 (favourable) Expressed in all Mixed skeletal muscle: 29.7 Mixed +FMNL3 DKFZp762B245, MGC45819, WBP3 ENSG00000161791 Formin like 3 12 49636499-49708165 Predicted intracellular proteins Evidence at protein level HPA002552, HPA023201 Uncertain Supported Golgi apparatus
Vesicles
Plasma membrane
Cytosol Renal cancer:3.58e-5 (unfavourable) Expressed in all Mixed lymph node: 28.0 Mixed +AQP5 ENSG00000161798 Aquaporin 5 12 49961870-49965681 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA065008 Enhanced Approved Plasma membrane Head and neck cancer:1.75e-5 (favourable) Tissue enhanced Group enriched 8 salivary gland: 255.6;stomach: 53.3;testis: 176.4 breast: 21.1 Group enriched 9 CAPAN-2: 7.6;REH: 9.2 +RACGAP1 MgcRacGAP ENSG00000161800 Rac GTPase activating protein 1 12 49976923-50033136 Predicted intracellular proteins Evidence at protein level CAB025859, HPA039427, HPA043912 Enhanced Enhanced Nucleoplasm Renal cancer:3.98e-8 (unfavourable), Liver cancer:1.86e-6 (unfavourable), Pancreatic cancer:4.12e-6 (unfavourable), Breast cancer:1.51e-4 (unfavourable) Expressed in all Tissue enhanced testis: 84.3 lymph node: 28.6 Expressed in all +OR7G1 OR19-15, OR7G1P ENSG00000161807 Olfactory receptor family 7 subfamily G member 1 19 9114828-9115763 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +LARP4 PP13296 ENSG00000161813 La ribonucleoprotein domain family member 4 12 50392383-50480004 Predicted intracellular proteins Evidence at protein level HPA039306, HPA039673 Approved Enhanced Cytosol Expressed in all Expressed in all adrenal gland: 36.6 Expressed in all +GRASP Tamalin ENSG00000161835 General receptor for phosphoinositides 1 associated scaffold protein 12 52006940-52015889 Predicted intracellular proteins Evidence at protein level HPA040664, HPA062028 Approved Approved Nuclear bodies
Vesicles Expressed in all Mixed adipose tissue: 21.6 Cell line enhanced HUVEC TERT2: 27.8;TIME: 19.7;WM-115: 43.6 +RAVER1 KIAA1978 ENSG00000161847 Ribonucleoprotein, PTB binding 1 19 10316212-10333640 Predicted intracellular proteins Evidence at protein level HPA043575, HPA049457 Enhanced Supported Nucleoplasm Expressed in all Mixed small intestine: 20.2 Expressed in all +KRT84 Hb-4, KRTHB4 ENSG00000161849 Keratin 84 12 52377812-52385652 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039714 Supported Tissue enhanced Not detected tonsil: 0.5 Not detected +KRT82 Hb-2, KRTHB2 ENSG00000161850 Keratin 82 12 52393931-52406355 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058715, HPA067230 Enhanced Not detected Not detected placenta,testis: 0.1 Not detected +SYCE2 CESC1 ENSG00000161860 Synaptonemal complex central element protein 2 19 12898786-12919276 Predicted intracellular proteins Evidence at protein level HPA042080, HPA062919 Enhanced Supported Nucleus Cervical cancer:3.85e-5 (favourable), Endometrial cancer:9.91e-4 (unfavourable) Mixed Tissue enriched 15 testis: 38.9 cerebral cortex: 2.5 Cell line enhanced EFO-21: 11.1;SiHa: 12.6 +SPC24 FLJ90806, SPBC24 ENSG00000161888 SPC24, NDC80 kinetochore complex component 19 11131520-11155808 Predicted intracellular proteins Evidence at protein level HPA051234 Approved Supported Nucleus
Nucleoli Renal cancer:0.00e+0 (unfavourable), Pancreatic cancer:1.22e-4 (unfavourable), Liver cancer:1.46e-4 (unfavourable), Cervical cancer:3.59e-4 (favourable) Expressed in all Mixed bone marrow: 16.6 Mixed +IP6K3 IHPK3, INSP6K3 ENSG00000161896 Inositol hexakisphosphate kinase 3 6 33721670-33746905 Enzymes, Predicted intracellular proteins Evidence at protein level HPA053644 Approved Approved Nucleoplasm
Cytosol Renal cancer:6.09e-4 (unfavourable) Mixed Tissue enhanced skeletal muscle: 32.4;thyroid gland: 21.9 heart muscle: 9.1 Cell line enhanced HHSteC: 18.4;LHCN-M2: 30.1;RH-30: 15.3 +LEMD2 dJ482C21.1, NET25 ENSG00000161904 LEM domain containing 2 6 33771202-33789136 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017340 Supported Enhanced Nuclear membrane Renal cancer:1.12e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 69.8 Expressed in all +ALOX15 15-LOX-1 ENSG00000161905 Arachidonate 15-lipoxygenase 17 4630902-4642294 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004962, CAB004963, HPA013859 Approved Mixed Tissue enhanced fallopian tube: 19.6;lung: 9.8 breast: 4.7 Group enriched 7 HMC-1: 13.6;MCF7: 10.8;T-47d: 3.9 +TREML1 dJ238O23.3, TLT1 ENSG00000161911 Triggering receptor expressed on myeloid cells like 1 6 41149342-41154337 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA016700, HPA017860 Enhanced Mixed Tissue enhanced bone marrow: 5.0;lymph node: 6.5 tonsil: 4.4 Cell line enriched 176 HEL: 59.6 +ZNF653 Zip67 ENSG00000161914 Zinc finger protein 653 19 11483427-11505923 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023631, HPA023635 Uncertain Supported Nucleus Endometrial cancer:4.15e-4 (favourable), Colorectal cancer:8.37e-4 (unfavourable), Urothelial cancer:8.74e-4 (favourable) Expressed in all Mixed testis: 19.0 Expressed in all +MED11 HSPC296, MGC88387 ENSG00000161920 Mediator complex subunit 11 17 4731428-4733610 Predicted intracellular proteins Evidence at protein level HPA056669 Uncertain Approved Nucleoplasm
Nuclear bodies Endometrial cancer:1.86e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 47.9 Expressed in all +CXCL16 CXCLG16, SR-PSOX, SRPSOX ENSG00000161921 C-X-C motif chemokine ligand 16 17 4733526-4739922 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA053253, HPA066315 Approved Approved Golgi apparatus
Vesicles Expressed in all Mixed lung: 106.0 Cell line enhanced A-431: 84.5;CACO-2: 54.2;HaCaT: 93.1 +SCIMP C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783 ENSG00000161929 SLP adaptor and CSK interacting membrane protein 17 5208961-5234860 Predicted membrane proteins Evidence at protein level HPA006117 Enhanced Mixed Tissue enhanced spleen: 68.5 lymph node: 45.9 Cell line enhanced U-698: 7.7 +RNASEK-C17orf49 ENSG00000161939 RNASEK-C17orf49 readthrough 17 7012635-7017520 Predicted membrane proteins Evidence at protein level HPA022961, HPA024457 Uncertain Uncertain Nucleoplasm
Cytosol Not detected Not detected endometrium,small intestine,testis: 0.6 Cell line enhanced U-87 MG: 3.6 +BCL6B BAZF, ZBTB28, ZNF62 ENSG00000161940 B-cell CLL/lymphoma 6B 17 7023020-7030290 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA059147, HPA075112 Uncertain Approved Vesicles Head and neck cancer:8.56e-5 (favourable), Renal cancer:4.04e-4 (unfavourable) Expressed in all Mixed adipose tissue: 34.6 Group enriched 14 HEL: 16.2;HMC-1: 46.5;HUVEC TERT2: 79.9;TIME: 30.9 +ASGR2 CLEC4H2 ENSG00000161944 Asialoglycoprotein receptor 2 17 7101322-7115700 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014899, HPA015998 Enhanced Supported Endoplasmic reticulum
Plasma membrane Tissue enriched Tissue enriched 11 liver: 317.7 gallbladder: 28.1 Cell line enriched 7 Hep G2: 356.8 +TNFSF13 APRIL, CD256 ENSG00000161955 Tumor necrosis factor superfamily member 13 17 7558292-7561608 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004863 Uncertain Renal cancer:1.30e-9 (favourable), Glioma:8.28e-4 (unfavourable) Expressed in all Expressed in all lung: 149.6 Cell line enhanced EFO-21: 41.1;RPTEC TERT1: 83.9 +SENP3 DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3, Ulp1 ENSG00000161956 SUMO1/sentrin/SMT3 specific peptidase 3 17 7561875-7571969 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060290 Supported Supported Nucleus
Nucleoli Pancreatic cancer:6.22e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 57.4 Expressed in all +FGF11 FHF3, FLJ16061, MGC102953, MGC45269 ENSG00000161958 Fibroblast growth factor 11 17 7438273-7444937 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA066605, HPA075188 Enhanced Approved Centrosome Mixed Tissue enhanced adrenal gland: 17.3;skin: 13.7 cerebral cortex: 10.3 Cell line enhanced HaCaT: 16.3 +EIF4A1 DDX2A, EIF-4A, EIF4A ENSG00000161960 Eukaryotic translation initiation factor 4A1 17 7572706-7579005 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011689, HPA068286 Uncertain Approved Cytosol Renal cancer:1.76e-8 (unfavourable) Expressed in all Expressed in all smooth muscle: 458.2 Expressed in all +RPL26 L26 ENSG00000161970 Ribosomal protein L26 17 8377520-8383213 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA030449, CAB037301 Supported Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all breast: 5194.8 Expressed in all +CCDC42 CCDC42A, FLJ32734 ENSG00000161973 Coiled-coil domain containing 42 17 8729934-8745219 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 364 testis: 128.6 lung,spleen: 0.3 Not detected +POLR3K RPC11 ENSG00000161980 RNA polymerase III subunit K 16 46407-53628 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA005891 Approved Uncertain Nucleus
Cytosol Expressed in all Expressed in all lymph node: 20.5 Expressed in all +SNRNP25 C16orf33, U11/U12-25K ENSG00000161981 Small nuclear ribonucleoprotein U11/U12 subunit 25 16 53010-57669 Predicted intracellular proteins Evidence at protein level HPA041183, HPA044248 Uncertain Supported Nucleoplasm
Cytokinetic bridge
Cytosol Renal cancer:1.16e-5 (favourable), Cervical cancer:1.95e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 55.4 Expressed in all +PRR35 C16orf11 ENSG00000161992 Proline rich 35 16 560422-565528 Predicted intracellular proteins Evidence at transcript level HPA069297 Uncertain Not detected Tissue enhanced kidney: 2.9 testis: 0.8 Not detected +WDR90 C16orf15, C16orf16, C16orf17, C16orf18, C16orf19, FLJ36483, KIAA1924 ENSG00000161996 WD repeat domain 90 16 649311-667833 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049362, HPA061785 Approved Approved Nuclear speckles Head and neck cancer:2.70e-4 (favourable) Expressed in all Mixed testis: 28.1 Mixed +JMJD8 C16orf20 ENSG00000161999 Jumonji domain containing 8 16 681671-684528 Predicted secreted proteins Evidence at transcript level Expressed in all Expressed in all parathyroid gland: 59.8 Mixed +CCDC78 C16orf25, FLJ34512 ENSG00000162004 Coiled-coil domain containing 78 16 722582-726954 Disease related genes, Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 11 fallopian tube: 97.7 lung: 8.5 Cell line enhanced SCLC-21H: 13.2 +MSLNL C16orf37, MPFL ENSG00000162006 Mesothelin-like 16 769428-783370 Predicted membrane proteins Evidence at transcript level Tissue enhanced Not detected epididymis: 0.8 Group enriched 5 CAPAN-2: 9.8;HeLa: 4.3 +SSTR5 ENSG00000162009 Somatostatin receptor 5 16 1078781-1080142 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA066503 Supported Plasma membrane Mixed Tissue enhanced adrenal gland: 1.2 kidney: 0.5 Group enriched 15 Hep G2: 10.4;PC-3: 50.7 +SPSB3 C16orf31, SSB-3 ENSG00000162032 SplA/ryanodine receptor domain and SOCS box containing 3 16 1776712-1793700 Predicted intracellular proteins Evidence at protein level HPA046602 Approved Approved Mitochondria Mixed Expressed in all adrenal gland: 29.1 Mixed +MEIOB C16orf73, MGC35212 ENSG00000162039 Meiosis specific with OB domains 16 1833983-1884294 Predicted intracellular proteins Evidence at protein level HPA042547 Approved Nucleus
Nucleoli Not detected Tissue enriched 61 testis: 71.4 kidney: 1.1 Group enriched 5 HMC-1: 24.7;K-562: 85.3;THP-1: 55.0 +HS3ST6 HS3ST5 ENSG00000162040 Heparan sulfate-glucosamine 3-sulfotransferase 6 16 1911463-1918440 Enzymes, Predicted intracellular proteins Evidence at protein level Cervical cancer:3.73e-4 (favourable) Tissue enhanced Tissue enriched 10 skin: 9.5 fallopian tube: 0.9 Not detected +C16orf59 FLJ13909 ENSG00000162062 Chromosome 16 open reading frame 59 16 2460080-2464963 Predicted intracellular proteins Evidence at protein level HPA051394, HPA055389 Approved Approved Nucleoplasm
Cell Junctions Liver cancer:2.43e-5 (unfavourable), Lung cancer:7.58e-4 (unfavourable) Expressed in all Tissue enhanced testis: 5.5 bone marrow,lymph node: 2.5 Mixed +CCNF FBX1, FBXO1 ENSG00000162063 Cyclin F 16 2429394-2458854 Predicted intracellular proteins Evidence at protein level HPA060596, HPA070495, HPA071600 Enhanced Supported Centrosome Liver cancer:7.46e-7 (unfavourable) Expressed in all Mixed lymph node,tonsil: 8.6 Expressed in all +TBC1D24 DFNA65, DFNB86, KIAA1171, TLDC6 ENSG00000162065 TBC1 domain family member 24 16 2475051-2509560 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044712, HPA068080 Uncertain Supported Plasma membrane
Cell Junctions Breast cancer:3.22e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 23.0 Expressed in all +AMDHD2 CGI-14 ENSG00000162066 Amidohydrolase domain containing 2 16 2520357-2531422 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041184, HPA041321 Enhanced Approved Nucleoli
Cytosol Cervical cancer:5.19e-4 (favourable) Expressed in all Mixed testis: 15.9 Mixed +NTN3 NTN2L ENSG00000162068 Netrin 3 16 2471499-2474145 Predicted secreted proteins Evidence at protein level HPA050817 Uncertain Mixed Not detected testis: 0.6 Group enriched 5 REH: 4.8;SCLC-21H: 7.6;SH-SY5Y: 3.8 +BICDL2 CCDC64B ENSG00000162069 BICD family like cargo adaptor 2 16 3027682-3036926 Predicted intracellular proteins Evidence at protein level HPA043251 Uncertain Approved Intermediate filaments
Actin filaments
Cytosol Urothelial cancer:9.04e-4 (favourable) Mixed Tissue enhanced skin: 28.5 stomach: 17.2 Cell line enhanced BEWO: 14.7;CAPAN-2: 12.6;HaCaT: 19.6;MCF7: 17.2;T-47d: 13.1 +PAQR4 FLJ30002 ENSG00000162073 Progestin and adipoQ receptor family member 4 16 2969245-2973489 Predicted membrane proteins Evidence at protein level HPA068394 Approved Vesicles Renal cancer:3.01e-6 (unfavourable), Stomach cancer:1.70e-4 (favourable), Liver cancer:6.86e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 54.0;parathyroid gland: 65.2 prostate,skin: 19.2 Mixed +FLYWCH2 ENSG00000162076 FLYWCH family member 2 16 2883186-2899382 Predicted intracellular proteins Evidence at protein level HPA041354 Uncertain Approved Nucleus Pancreatic cancer:1.87e-5 (favourable), Cervical cancer:9.38e-4 (favourable) Expressed in all Expressed in all spleen: 35.1 Expressed in all +ZG16B HRPE773, JCLN2, PRO1567 ENSG00000162078 Zymogen granule protein 16B 16 2830169-2839585 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041125, HPA053549 Enhanced Approved Nucleoplasm
Vesicles Endometrial cancer:3.48e-6 (favourable) Tissue enhanced Tissue enriched 225 salivary gland: 19471.0 prostate: 86.7 Cell line enhanced MCF7: 20.7;SK-BR-3: 18.1;T-47d: 20.8 +ZNF75A FLJ31529 ENSG00000162086 Zinc finger protein 75a 16 3305406-3318852 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001665 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center Expressed in all Expressed in all parathyroid gland: 46.7 Mixed +ADCY9 AC9 ENSG00000162104 Adenylate cyclase 9 16 3953387-4116185 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041328, HPA044225 Approved Approved Cytosol Renal cancer:5.24e-8 (favourable), Endometrial cancer:2.55e-5 (unfavourable) Expressed in all Mixed thyroid gland: 31.9 Mixed +SHANK2 CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3 ENSG00000162105 SH3 and multiple ankyrin repeat domains 2 11 70467856-71252577 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008174 Approved Renal cancer:1.94e-6 (favourable) Mixed Tissue enhanced cerebral cortex: 20.9 thyroid gland: 11.6 Cell line enhanced Karpas-707: 16.4;RT4: 16.7;T-47d: 15.1 +CLPB ANKCLB, FLJ13152, HSP78, SKD3 ENSG00000162129 ClpB homolog, mitochondrial AAA ATPase chaperonin 11 72292425-72434680 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039005, HPA039006, HPA064571 Enhanced Renal cancer:8.36e-8 (favourable) Expressed in all Tissue enriched 10 testis: 176.6 parathyroid gland: 18.5 Expressed in all +NEU3 ENSG00000162139 Neuraminidase 3 11 74988134-75018893 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038729, HPA038730, HPA070381 Uncertain Supported Nucleoplasm
Vesicles Pancreatic cancer:5.98e-4 (favourable) Expressed in all Mixed parathyroid gland: 25.4 Expressed in all +CYB561A3 CYBASC3 ENSG00000162144 Cytochrome b561 family member A3 11 61348745-61362299 Predicted membrane proteins Evidence at protein level HPA052548 Approved Expressed in all Expressed in all adrenal gland: 187.1 Expressed in all +PPP1R32 C11orf66, FLJ32771, IIIG9 ENSG00000162148 Protein phosphatase 1 regulatory subunit 32 11 61481120-61490931 Predicted intracellular proteins Evidence at protein level HPA039068 Enhanced Endometrial cancer:4.13e-4 (favourable) Mixed Tissue enhanced fallopian tube: 64.8;testis: 87.5 epididymis: 15.5 Mixed +ASRGL1 ALP, ALP1, FLJ22316 ENSG00000162174 Asparaginase like 1 11 62337448-62393412 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029725, HPA055572, CAB070192 Enhanced Approved Nucleoplasm
Microtubules Renal cancer:4.32e-7 (favourable), Endometrial cancer:1.56e-5 (favourable), Colorectal cancer:6.14e-4 (favourable), Liver cancer:9.46e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 181.6 Cell line enhanced HAP1: 86.4;SCLC-21H: 132.5 +GNG3 ENSG00000162188 G protein subunit gamma 3 11 62707658-62709201 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Tissue enriched Tissue enriched 17 cerebral cortex: 315.2 adrenal gland: 19.0 Group enriched 7 Karpas-707: 104.6;SCLC-21H: 335.7 +UBXN1 2B28, LOC51035, SAKS1, UBXD10 ENSG00000162191 UBX domain protein 1 11 62676498-62679117 Predicted intracellular proteins Evidence at protein level HPA012669 Approved Approved Nucleoplasm Expressed in all Expressed in all ovary: 145.9 Expressed in all +LBHD1 C11orf48, MGC2477 ENSG00000162194 LBH domain containing 1 11 62662817-62672255 Predicted intracellular proteins Evidence at protein level HPA012127, HPA023592 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Mixed parathyroid gland: 9.3 Mixed +TTC9C MGC29649 ENSG00000162222 Tetratricopeptide repeat domain 9C 11 62728069-62740293 Predicted intracellular proteins Evidence at protein level HPA055169 Approved Approved Nucleoplasm Renal cancer:4.67e-7 (unfavourable), Stomach cancer:4.15e-5 (favourable) Expressed in all Expressed in all thyroid gland: 31.0 Expressed in all +TAF6L PAF65A ENSG00000162227 TATA-box binding protein associated factor 6 like 11 62771303-62787342 Predicted intracellular proteins Evidence at protein level HPA067239 Approved Supported Nucleoplasm Head and neck cancer:8.98e-5 (favourable) Expressed in all Expressed in all skin: 11.9 Expressed in all +NXF1 DKFZp667O0311, Mex67, TAP ENSG00000162231 Nuclear RNA export factor 1 11 62792123-62806302 Predicted intracellular proteins, Transporters Evidence at protein level CAB016327, HPA061593 Supported Supported Nucleoplasm Pancreatic cancer:4.08e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 147.7 Expressed in all +STX5 SED5, STX5A ENSG00000162236 Syntaxin 5 11 62806897-62832088 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001358 Uncertain Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all thyroid gland: 59.1 Expressed in all +SLC25A45 ENSG00000162241 Solute carrier family 25 member 45 11 65375192-65383701 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA050821 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:2.83e-4 (favourable) Expressed in all Expressed in all spleen: 12.4 Cell line enhanced HDLM-2: 16.2;Karpas-707: 16.4 +RPL29 HIP, HUMRPL29, L29, RPL29P10 ENSG00000162244 Ribosomal protein L29 3 51993600-51995942 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA069064 Approved Enhanced Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 2738.5 Expressed in all +ITIH3 H3P ENSG00000162267 Inter-alpha-trypsin inhibitor heavy chain 3 3 52794768-52809009 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA017373 Approved Approved Renal cancer:4.49e-8 (unfavourable) Tissue enriched Tissue enriched 51 liver: 413.6 spleen: 8.0 Cell line enriched 18 Hep G2: 11.7 +SYVN1 DER3, HRD1 ENSG00000162298 Synoviolin 1 11 65121780-65134533 Enzymes, Predicted membrane proteins Evidence at protein level HPA005480, HPA024300, CAB037030 Enhanced Supported Nucleoplasm
Endoplasmic reticulum
Plasma membrane Head and neck cancer:6.88e-4 (favourable) Expressed in all Expressed in all tonsil: 73.8 Expressed in all +ZFPL1 D11S750, MCG4 ENSG00000162300 Zinc finger protein like 1 11 65084223-65088400 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014909, HPA017347 Enhanced Enhanced Golgi apparatus Liver cancer:9.12e-6 (unfavourable), Renal cancer:2.73e-5 (favourable) Expressed in all Expressed in all fallopian tube: 31.7 Expressed in all +RPS6KA4 MSK2, RSK-B ENSG00000162302 Ribosomal protein S6 kinase A4 11 64359148-64372215 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008649, HPA023225 Approved Supported Nucleus
Cytosol Liver cancer:8.17e-4 (unfavourable), Lung cancer:9.27e-4 (unfavourable) Expressed in all Expressed in all spleen: 23.1 Expressed in all +LRP5 BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2 ENSG00000162337 LDL receptor related protein 5 11 68312609-68449275 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013001, HPA030505 Approved Renal cancer:3.55e-10 (favourable) Expressed in all Expressed in all small intestine: 49.8 Mixed +TPCN2 TPC2 ENSG00000162341 Two pore segment channel 2 11 69048897-69162440 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA016561, HPA027080 Enhanced Approved Nucleoli Ovarian cancer:1.49e-4 (unfavourable), Head and neck cancer:2.96e-4 (unfavourable) Expressed in all Mixed endometrium: 10.2 Expressed in all +FGF19 ENSG00000162344 Fibroblast growth factor 19 11 69698232-69704642 Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA036082 Approved Mixed Tissue enriched 28 gallbladder: 262.2 small intestine: 9.4 Cell line enriched 14 CAPAN-2: 87.6 +CYP4A22 ENSG00000162365 Cytochrome P450 family 4 subfamily A member 22 1 47137435-47149741 Enzymes, Predicted membrane proteins Evidence at protein level Tissue enriched Group enriched 16 kidney: 33.5;liver: 109.1 epididymis: 4.5 Cell line enriched 5 RH-30: 1.2 +PDZK1IP1 DD96, MAP17, SPAP ENSG00000162366 PDZK1 interacting protein 1 1 47183593-47191044 Predicted membrane proteins Evidence at protein level HPA014907 Enhanced Approved Nuclear speckles
Cytosol Pancreatic cancer:3.45e-4 (unfavourable), Glioma:9.46e-4 (unfavourable) Expressed in all Group enriched 6 gallbladder: 297.8;kidney: 1052.9 esophagus: 121.2 Group enriched 5 EFO-21: 138.3;RPTEC TERT1: 370.1 +TAL1 bHLHa17, SCL, TCL5 ENSG00000162367 TAL bHLH transcription factor 1, erythroid differentiation factor 1 47216290-47232220 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017805, HPA047866, HPA073983 Approved Supported Nucleus Mixed Tissue enhanced bone marrow: 17.7 placenta: 10.0 Cell line enhanced HEL: 137.6;HMC-1: 62.0;K-562: 43.6;TIME: 28.0 +CMPK1 CMPK, UMP-CMPK ENSG00000162368 Cytidine/uridine monophosphate kinase 1 1 47333797-47378839 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA053730, HPA058604 Approved Supported Nucleus Glioma:8.67e-4 (favourable) Expressed in all Expressed in all small intestine: 169.1 Expressed in all +BEND5 C1orf165, FLJ11588 ENSG00000162373 BEN domain containing 5 1 48727523-48776969 Predicted intracellular proteins Evidence at protein level HPA054347, HPA058007 Uncertain Urothelial cancer:8.30e-6 (favourable), Breast cancer:2.50e-5 (favourable), Pancreatic cancer:1.29e-4 (favourable), Lung cancer:1.29e-4 (favourable) Mixed Mixed cerebral cortex: 6.0 Cell line enhanced AF22: 3.2;HDLM-2: 10.2;MOLT-4: 3.6;REH: 5.7;SH-SY5Y: 3.1 +ELAVL4 HUD, PNEM ENSG00000162374 ELAV like RNA binding protein 4 1 50048014-50203786 Predicted intracellular proteins Evidence at protein level CAB004442, HPA043047 Enhanced Approved Nucleoplasm
Vesicles Group enriched Group enriched 9 adrenal gland: 10.7;cerebral cortex: 53.3;testis: 10.9 appendix: 2.9 Cell line enriched 21 SH-SY5Y: 131.1 +COA7 C1orf163, FLJ12439, RESA1, SELRC1 ENSG00000162377 Cytochrome c oxidase assembly factor 7 (putative) 1 52684451-52698366 Predicted intracellular proteins Evidence at protein level HPA028154, HPA029926 Approved Approved Nucleus
Mitochondria Liver cancer:7.01e-5 (unfavourable), Stomach cancer:4.35e-4 (favourable), Endometrial cancer:8.55e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 14.7 Expressed in all +ZYG11B FLJ13456, ZYG11 ENSG00000162378 Zyg-11 family member B, cell cycle regulator 1 52726467-52827342 Predicted intracellular proteins Evidence at protein level HPA028156 Uncertain Approved Golgi apparatus
Intermediate filaments Renal cancer:9.80e-7 (favourable), Colorectal cancer:5.42e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 29.0 Expressed in all +SLC1A7 EAAT5 ENSG00000162383 Solute carrier family 1 member 7 1 53087179-53142632 Predicted membrane proteins, Transporters Evidence at protein level HPA049124 Supported Tissue enhanced Tissue enhanced gallbladder: 8.5 small intestine: 3.5 Cell line enriched 8 HHSteC: 21.0 +C1orf123 FLJ20580 ENSG00000162384 Chromosome 1 open reading frame 123 1 53214099-53220617 Predicted intracellular proteins Evidence at protein level HPA043835 Uncertain Approved Cytosol Renal cancer:1.53e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 89.3 Expressed in all +MAGOH MAGOH1, MAGOHA ENSG00000162385 Mago homolog, exon junction complex core component 1 53226892-53238610 Predicted intracellular proteins, Transporters Evidence at protein level CAB015425, HPA043036, HPA047754 Approved Supported Nucleus Renal cancer:1.45e-5 (unfavourable), Breast cancer:1.85e-4 (favourable) Expressed in all Expressed in all lymph node: 82.2 Expressed in all +ACOT11 BFIT, BFIT1, KIAA0707, STARD14, THEA, THEM1 ENSG00000162390 Acyl-CoA thioesterase 11 1 54542257-54639192 Predicted intracellular proteins Evidence at protein level HPA041047 Enhanced Supported Cytosol Renal cancer:3.07e-8 (favourable), Colorectal cancer:9.37e-4 (favourable) Mixed Mixed duodenum: 36.4 Cell line enhanced RT4: 32.0 +FAM151A C1orf179, MGC27169 ENSG00000162391 Family with sequence similarity 151 member A 1 54609182-54623556 Predicted intracellular proteins Evidence at protein level HPA016840 Approved Uncertain Nucleoplasm Renal cancer:4.09e-5 (favourable) Group enriched Group enriched 14 kidney: 175.3;small intestine: 66.8 liver: 8.5 Cell line enriched 41 CACO-2: 63.5 +PARS2 DKFZp727A071 ENSG00000162396 Prolyl-tRNA synthetase 2, mitochondrial (putative) 1 54756898-54764514 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028308, HPA028314, HPA028518 Uncertain Approved Nucleoli fibrillar center
Mitochondria Renal cancer:1.24e-6 (favourable), Colorectal cancer:1.26e-5 (favourable), Liver cancer:2.34e-4 (unfavourable) Expressed in all Mixed testis: 8.0 Mixed +LEXM C1orf177, FLJ40201, LEM ENSG00000162398 Lymphocyte expansion molecule 1 54806063-54842252 Predicted intracellular proteins Evidence at protein level HPA035889, HPA035890 Uncertain Mixed Group enriched 5 esophagus: 10.5;testis: 7.0 duodenum: 1.6 Not detected +BSND BART, DFNB73 ENSG00000162399 Barttin CLCNK type accessory beta subunit 1 54998933-55010883 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA053836, HPA060617 Enhanced Tissue enriched Tissue enriched 7 kidney: 10.2 salivary gland: 1.5 Cell line enriched 15 RPMI-8226: 8.0 +USP24 KIAA1057 ENSG00000162402 Ubiquitin specific peptidase 24 1 55066359-55215113 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026723, HPA028428, HPA067124 Approved Supported Nucleoplasm
Cytosol Liver cancer:1.34e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 38.1 Expressed in all +PLPP3 LPP3, PAP-2b, PPAP2B ENSG00000162407 Phospholipid phosphatase 3 1 56494747-56645301 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA028892, HPA072751 Uncertain Supported Golgi apparatus Renal cancer:4.59e-4 (favourable) Expressed in all Expressed in all thyroid gland: 546.5 Group enriched 8 ASC diff: 484.3;ASC TERT1: 245.1;HSkMC: 316.7;U-138 MG: 173.1;U-2197: 610.0 +NOL9 FLJ23323, Grc3, NET6 ENSG00000162408 Nucleolar protein 9 1 6521347-6554535 Predicted intracellular proteins Evidence at protein level HPA036347 Supported Nucleoli
Intermediate filaments Liver cancer:3.69e-5 (unfavourable) Expressed in all Mixed spleen: 8.4 Expressed in all +PRKAA2 AMPK, AMPKa2, PRKAA ENSG00000162409 Protein kinase AMP-activated catalytic subunit alpha 2 1 56645322-56715335 Enzymes, Predicted membrane proteins Evidence at protein level HPA044540 Approved Supported Nuclear speckles
Golgi apparatus Renal cancer:4.95e-5 (favourable), Endometrial cancer:4.80e-4 (unfavourable), Liver cancer:5.30e-4 (unfavourable) Mixed Tissue enhanced heart muscle: 26.5 parathyroid gland: 15.0 Cell line enhanced RPTEC TERT1: 10.7 +KLHL21 KIAA0469 ENSG00000162413 Kelch like family member 21 1 6590724-6614607 Predicted intracellular proteins Evidence at protein level HPA051364, HPA059307 Uncertain Supported Centrosome Renal cancer:1.71e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 39.8 Mixed +ZSWIM5 KIAA1511 ENSG00000162415 Zinc finger SWIM-type containing 5 1 45016399-45306209 Predicted intracellular proteins Evidence at transcript level HPA018211 Uncertain Approved Nuclear speckles Expressed in all Mixed parathyroid gland: 15.8 Cell line enhanced SCLC-21H: 8.6 +GMEB1 P96PIF, PIF96 ENSG00000162419 Glucocorticoid modulatory element binding protein 1 1 28668732-28719353 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044811, HPA052975 Supported Enhanced Nucleoplasm Liver cancer:8.91e-7 (unfavourable), Endometrial cancer:1.94e-4 (favourable) Expressed in all Mixed bone marrow: 8.5 Expressed in all +SLC45A1 DNB5 ENSG00000162426 Solute carrier family 45 member 1 1 8317826-8344167 Predicted membrane proteins, Transporters Evidence at transcript level Mixed Tissue enhanced cerebral cortex: 11.7 endometrium: 3.2 Cell line enhanced HHSteC: 4.1;U-87 MG: 6.3 +SELENON MDRS1, RSMD1, RSS, SELN, SEPN1 ENSG00000162430 Selenoprotein N 1 25800176-25818224 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA058076 Approved Supported Cytosol Liver cancer:3.40e-5 (unfavourable), Endometrial cancer:2.23e-4 (favourable) Expressed in all Expressed in all smooth muscle: 81.2 Mixed +AK4 AK3, AK3L1 ENSG00000162433 Adenylate kinase 4 1 65147549-65232145 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042753, HPA049461 Enhanced Supported Mitochondria Pancreatic cancer:4.34e-5 (unfavourable), Cervical cancer:4.17e-4 (unfavourable), Renal cancer:4.36e-4 (unfavourable), Stomach cancer:4.87e-4 (unfavourable), Head and neck cancer:8.83e-4 (unfavourable) Expressed in all Tissue enhanced kidney: 190.7 liver: 53.7 Cell line enhanced Hep G2: 141.9 +JAK1 JAK1A, JAK1B, JTK3 ENSG00000162434 Janus kinase 1 1 64833229-64966504 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013088 Approved Renal cancer:2.67e-4 (favourable), Colorectal cancer:2.81e-4 (favourable), Breast cancer:9.63e-4 (favourable) Expressed in all Expressed in all lymph node: 115.6 Expressed in all +RAVER2 FLJ10770, KIAA1579 ENSG00000162437 Ribonucleoprotein, PTB binding 2 1 64745095-64833232 Predicted intracellular proteins Evidence at protein level HPA045785 Approved Approved Nucleoplasm Renal cancer:5.14e-6 (favourable) Expressed in all Mixed rectum: 29.4 Mixed +CTRC CLCR, ELA4 ENSG00000162438 Chymotrypsin C 1 15438439-15449242 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA046920 Enhanced Tissue enriched Tissue enriched 361 pancreas: 18186.4 ovary: 50.3 Not detected +LZIC MGC15436 ENSG00000162441 Leucine zipper and CTNNBIP1 domain containing 1 9922113-9943407 Predicted intracellular proteins Evidence at protein level HPA028184, HPA058614 Approved Approved Nucleoplasm
Cytosol Liver cancer:2.47e-5 (unfavourable), Renal cancer:3.56e-5 (favourable) Expressed in all Expressed in all testis: 120.1 Expressed in all +RBP7 CRBPIV ENSG00000162444 Retinol binding protein 7 1 9997206-10016020 Predicted intracellular proteins Evidence at protein level HPA034749 Enhanced Uncertain Nuclear speckles
Cytosol Colorectal cancer:2.49e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 260.1 breast: 82.2 Cell line enhanced EFO-21: 12.5;SK-MEL-30: 7.2;T-47d: 32.2 +KNCN FLJ32011, KINO, L5 ENSG00000162456 Kinocilin 1 46545644-46551527 Predicted membrane proteins Evidence at transcript level HPA046357 Uncertain Not detected Not detected testis: 0.6 Not detected +FBLIM1 CAL, FBLP-1, migfilin ENSG00000162458 Filamin binding LIM protein 1 1 15756607-15786594 Predicted intracellular proteins Evidence at protein level HPA025287, HPA072750 Approved Enhanced Nucleoli fibrillar center
Cell Junctions
Focal adhesion sites Cervical cancer:4.07e-4 (unfavourable), Melanoma:6.15e-4 (unfavourable), Renal cancer:8.64e-4 (unfavourable) Expressed in all Mixed gallbladder: 101.8 Cell line enhanced HUVEC TERT2: 210.1;TIME: 323.6 +TMEM82 ENSG00000162460 Transmembrane protein 82 1 15742422-15747982 Predicted membrane proteins Evidence at protein level HPA060282 Uncertain Uncertain Nucleoplasm
Cytosol Renal cancer:3.80e-7 (favourable) Tissue enhanced Tissue enhanced duodenum: 23.0;liver: 9.0;small intestine: 19.4 kidney: 7.6 Cell line enriched 5 CACO-2: 2.6 +SLC25A34 DKFZp781A10161 ENSG00000162461 Solute carrier family 25 member 34 1 15736405-15741396 Predicted membrane proteins, Transporters Evidence at protein level HPA069806 Supported Mitochondria Mixed Tissue enhanced duodenum: 14.5;small intestine: 15.2 skeletal muscle: 8.2 Mixed +AKR7A3 ENSG00000162482 Aldo-keto reductase family 7 member A3 1 19282558-19289250 Predicted intracellular proteins Evidence at protein level HPA064638 Approved Cytosol Renal cancer:8.80e-7 (favourable) Group enriched Group enriched 5 duodenum: 170.4;gallbladder: 38.7;kidney: 49.0;liver: 44.8;small intestine: 106.8;stomach: 70.3 colon: 15.9 Cell line enhanced SK-BR-3: 12.6 +DRAXIN C1orf187, Draxin, FLJ34999, Neucrin ENSG00000162490 Dorsal inhibitory axon guidance protein 1 11691729-11725857 Predicted secreted proteins Evidence at protein level HPA014302 Uncertain Group enriched Tissue enhanced cerebral cortex: 1.5 testis: 0.6 Group enriched 5 NTERA-2: 28.2;REH: 5.8 +PDPN aggrus, Gp38, GP40, PA2.26, T1A-2 ENSG00000162493 Podoplanin 1 13583465-13617957 Predicted membrane proteins Evidence at protein level HPA007534, CAB008376 Enhanced Tissue enhanced Tissue enhanced placenta: 194.0 appendix: 78.6 Cell line enhanced AF22: 148.2;EFO-21: 336.7;HAP1: 260.6;HHSteC: 181.4;TIME: 199.2 +LRRC38 ENSG00000162494 Leucine rich repeat containing 38 1 13474977-13514048 Predicted membrane proteins Evidence at protein level HPA038778 Approved Mixed Group enriched 19 adrenal gland: 19.9;skeletal muscle: 10.5 placenta: 0.8 Cell line enhanced MOLT-4: 13.0;PC-3: 10.4;U-138 MG: 17.5 +DHRS3 RDH17, retSDR1, Rsdr1, SDR1, SDR16C1 ENSG00000162496 Dehydrogenase/reductase 3 1 12567910-12617731 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010844 Supported Approved Nucleoli
Mitochondria Thyroid cancer:2.65e-4 (favourable) Expressed in all Expressed in all adipose tissue: 99.9 Cell line enhanced CAPAN-2: 219.3;WM-115: 228.2 +MATN1 CMP, CRTM ENSG00000162510 Matrilin 1, cartilage matrix protein 1 30711277-30723587 Predicted secreted proteins Evidence at protein level HPA028580 Supported Tissue enhanced Not detected ovary: 0.8 Not detected +LAPTM5 ENSG00000162511 Lysosomal protein transmembrane 5 1 30732469-30757820 Predicted membrane proteins, Transporters Evidence at protein level HPA051293 Approved Approved Cytosol Renal cancer:5.89e-5 (unfavourable), Cervical cancer:3.40e-4 (favourable) Expressed in all Expressed in all bone marrow: 799.7 Cell line enhanced HEL: 921.8;HMC-1: 2049.8;REH: 698.6;U-698: 604.9 +SDC3 N-syndecan, SYND3 ENSG00000162512 Syndecan 3 1 30869467-30908761 Predicted membrane proteins Evidence at protein level HPA017087, CAB025786, HPA048085 Approved Approved Nucleoplasm
Mitochondria Renal cancer:1.71e-4 (unfavourable), Melanoma:2.36e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 136.4 Cell line enhanced SK-MEL-30: 167.1;WM-115: 290.3 +PEF1 PEF1A ENSG00000162517 Penta-EF-hand domain containing 1 1 31629862-31644896 Predicted intracellular proteins Evidence at protein level HPA061608 Approved Nucleoplasm
Vesicles
Cytosol Liver cancer:2.88e-4 (unfavourable), Cervical cancer:3.95e-4 (favourable) Expressed in all Expressed in all thyroid gland: 183.0 Expressed in all +SYNC SYNC1, SYNCOILIN ENSG00000162520 Syncoilin, intermediate filament protein 1 32680360-32703596 Predicted intracellular proteins Evidence at protein level HPA028311 Approved Approved Golgi apparatus
Vesicles
Plasma membrane Mixed Tissue enhanced smooth muscle: 74.1 skeletal muscle: 36.1 Cell line enhanced BJ hTERT+: 65.1;fHDF/TERT166: 91.5;U-138 MG: 98.1;WM-115: 67.5 +RBBP4 lin-53, NURF55, RbAp48 ENSG00000162521 RB binding protein 4, chromatin remodeling factor 1 32651142-32686211 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB006264, HPA060710, HPA060724 Enhanced Enhanced Nucleoplasm Liver cancer:1.89e-6 (unfavourable), Melanoma:6.45e-4 (unfavourable) Expressed in all Expressed in all testis: 138.7 Expressed in all +KIAA1522 ENSG00000162522 KIAA1522 1 32741885-32774970 Predicted intracellular proteins Evidence at protein level HPA032050, HPA032051, HPA064839 Approved Supported Nucleoplasm
Plasma membrane
Cell Junctions Liver cancer:6.29e-7 (unfavourable), Renal cancer:1.29e-5 (favourable), Pancreatic cancer:8.25e-5 (unfavourable) Expressed in all Mixed skin: 72.8 Cell line enhanced CAPAN-2: 110.4 +TSSK3 SPOGA3, STK22C ENSG00000162526 Testis specific serine kinase 3 1 32351521-32364312 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037516 Uncertain Approved Nucleus
Nucleoli
Nuclear bodies Not detected Tissue enhanced testis: 25.5 bone marrow: 5.5 Mixed +TMCO4 DKFZp686C23231 ENSG00000162542 Transmembrane and coiled-coil domains 4 1 19682213-19799945 Predicted membrane proteins Evidence at protein level HPA014601, HPA014620 Uncertain Approved Endoplasmic reticulum Renal cancer:4.12e-11 (favourable), Liver cancer:1.12e-4 (unfavourable), Urothelial cancer:3.64e-4 (favourable), Endometrial cancer:3.71e-4 (favourable) Expressed in all Mixed parathyroid gland: 37.0 Cell line enhanced CAPAN-2: 36.6 +UBXN10 FLJ25429, UBXD3 ENSG00000162543 UBX domain protein 10 1 20186085-20196048 Predicted intracellular proteins Evidence at protein level HPA028555, HPA028564 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cell Junctions Glioma:1.64e-4 (unfavourable), Endometrial cancer:2.02e-4 (favourable) Mixed Tissue enhanced fallopian tube: 79.1 testis: 25.5 Group enriched 6 HEL: 2.5;HMC-1: 6.3;K-562: 7.6;SCLC-21H: 6.6 +CAMK2N1 CaMKIINalpha ENSG00000162545 Calcium/calmodulin dependent protein kinase II inhibitor 1 1 20482391-20486220 Predicted intracellular proteins Evidence at protein level Head and neck cancer:1.37e-7 (unfavourable), Lung cancer:1.66e-4 (unfavourable), Liver cancer:5.49e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 321.1 small intestine: 95.6 Cell line enhanced AN3-CA: 195.3;CAPAN-2: 173.9 +ALPL HOPS, TNSALP ENSG00000162551 Alkaline phosphatase, liver/bone/kidney 1 21509372-21578412 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007105, HPA008765, CAB020829 Enhanced Approved Cytosol Melanoma:7.08e-4 (unfavourable) Expressed in all Tissue enhanced lung: 78.8 kidney: 47.2 Group enriched 8 HAP1: 31.9;HSkMC: 126.3;hTEC/SVTERT24-B: 139.0;LHCN-M2: 85.3;NTERA-2: 40.7;SCLC-21H: 103.8 +WNT4 WNT-4 ENSG00000162552 Wnt family member 4 1 22117305-22143969 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011397 Uncertain Approved Vesicles Pancreatic cancer:4.90e-4 (favourable), Melanoma:5.34e-4 (unfavourable) Mixed Tissue enhanced skin: 49.2 ovary: 15.3 Cell line enhanced HaCaT: 7.6;SCLC-21H: 12.2;SK-BR-3: 6.6 +TTLL10 FLJ36119, TTLL5 ENSG00000162571 Tubulin tyrosine ligase like 10 1 1173884-1197935 Predicted intracellular proteins Evidence at protein level HPA042712 Uncertain Endometrial cancer:1.61e-5 (favourable) Mixed Group enriched 8 fallopian tube: 14.2;testis: 27.9 lung: 2.7 Cell line enriched 31 SCLC-21H: 27.2 +SCNN1D dNaCh, ENaCdelta ENSG00000162572 Sodium channel epithelial 1 delta subunit 1 1280436-1292029 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA026884 Enhanced Supported Plasma membrane
Actin filaments Renal cancer:6.67e-5 (unfavourable), Pancreatic cancer:1.32e-4 (favourable), Head and neck cancer:1.60e-4 (favourable) Mixed Tissue enhanced testis: 13.8 cerebral cortex: 7.3 Mixed +MXRA8 DKFZp586E2023 ENSG00000162576 Matrix remodeling associated 8 1 1352689-1361777 Predicted membrane proteins Evidence at protein level HPA053958, HPA055780 Uncertain Approved Nucleoli Renal cancer:3.43e-6 (unfavourable), Urothelial cancer:9.87e-4 (unfavourable), Stomach cancer:9.93e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 57.4 endometrium: 44.5 Cell line enhanced BJ: 122.4;BJ hTERT+: 55.0;fHDF/TERT166: 56.2 +FAAP20 C1orf86, FLJ31031 ENSG00000162585 Fanconi anemia core complex associated protein 20 1 2184461-2212720 Predicted intracellular proteins Evidence at protein level HPA038829 Uncertain Supported Nucleoplasm
Nuclear bodies
Cell Junctions Pancreatic cancer:2.88e-4 (favourable), Liver cancer:4.57e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 13.0 Expressed in all +MEGF6 EGFL3 ENSG00000162591 Multiple EGF like domains 6 1 3489920-3611495 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA052129 Uncertain Approved Microtubules
Cytokinetic bridge Colorectal cancer:3.08e-4 (unfavourable), Head and neck cancer:6.57e-4 (favourable) Expressed in all Tissue enhanced skin: 48.2 gallbladder: 17.0 Cell line enhanced BJ: 37.3;HeLa: 26.6;U-2197: 36.2 +CCDC27 FLJ32825 ENSG00000162592 Coiled-coil domain containing 27 1 3746460-3771645 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 92 testis: 14.8 endometrium,prostate: 0.1 Cell line enriched 6 THP-1: 1.1 +IL23R IL-23R ENSG00000162594 Interleukin 23 receptor 1 67138907-67259979 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA056427 Uncertain Not detected Tissue enhanced adrenal gland: 2.1;testis: 2.8 rectum: 1.0 Cell line enhanced HMC-1: 8.0;K-562: 3.2;U-2197: 12.8 +DIRAS3 ARHI, NOEY2 ENSG00000162595 DIRAS family GTPase 3 1 68045962-68051631 Predicted intracellular proteins Evidence at protein level HPA028483, HPA028557, HPA029384 Approved Approved Nuclear membrane
Cytosol Breast cancer:9.21e-4 (favourable), Renal cancer:9.21e-4 (favourable) Mixed Tissue enhanced ovary: 57.2 parathyroid gland: 20.5 Cell line enhanced HSkMC: 9.3;TIME: 7.1;U-251 MG: 5.6;U-87 MG: 12.2 +C1orf87 CREF, MGC34837 ENSG00000162598 Chromosome 1 open reading frame 87 1 59987269-60073770 Predicted intracellular proteins Evidence at protein level HPA031366, HPA031368 Enhanced Tissue enhanced Tissue enriched 10 fallopian tube: 47.9 lung: 4.9 Not detected +NFIA KIAA1439, NFI-L ENSG00000162599 Nuclear factor I A 1 60865259-61462793 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006111, HPA008884 Enhanced Enhanced Nucleoplasm Urothelial cancer:2.03e-4 (unfavourable), Renal cancer:7.01e-4 (favourable), Head and neck cancer:7.30e-4 (favourable) Expressed in all Expressed in all thyroid gland: 53.8 Cell line enhanced AN3-CA: 77.5 +OMA1 FLJ33782, MPRP-1, YKR087C, ZMPOMA1 ENSG00000162600 OMA1 zinc metallopeptidase 1 58415384-58546802 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055120 Approved Approved Nucleoplasm
Mitochondria Breast cancer:1.63e-4 (favourable), Colorectal cancer:7.70e-4 (favourable), Lung cancer:8.52e-4 (favourable) Expressed in all Expressed in all prostate: 31.9 Expressed in all +MYSM1 KIAA1915 ENSG00000162601 Myb like, SWIRM and MPN domains 1 1 58654739-58700092 Enzymes, Predicted intracellular proteins Evidence at protein level HPA054291, HPA067133 Approved Supported Nucleoplasm
Plasma membrane Head and neck cancer:5.09e-5 (favourable) Expressed in all Mixed parathyroid gland: 11.2 Mixed +TM2D1 BBP ENSG00000162604 TM2 domain containing 1 1 61681046-61725423 Predicted membrane proteins Evidence at protein level HPA046058, HPA055621 Approved Enhanced Nucleoplasm Liver cancer:2.02e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 68.0 Expressed in all +USP1 ENSG00000162607 Ubiquitin specific peptidase 1 1 62436297-62451804 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028387, HPA028440 Approved Supported Nucleoplasm Liver cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all testis: 92.3 Expressed in all +FUBP1 FBP, FUBP ENSG00000162613 Far upstream element binding protein 1 1 77944055-77979110 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006149 Enhanced Enhanced Nucleoplasm Liver cancer:9.83e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 69.5 Expressed in all +NEXN NELIN, nexilin ENSG00000162614 Nexilin F-actin binding protein 1 77888513-77943895 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA011185 Approved Colorectal cancer:5.60e-4 (unfavourable) Mixed Tissue enhanced heart muscle: 298.6;skeletal muscle: 248.9 prostate: 109.6 Cell line enhanced BJ: 129.6;LHCN-M2: 116.4;RH-30: 106.0 +DNAJB4 HLJ1 ENSG00000162616 DnaJ heat shock protein family (Hsp40) member B4 1 77979175-78017964 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004995, HPA028383, HPA028385 Approved Enhanced Nucleoplasm
Plasma membrane
Cytosol Renal cancer:2.28e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 74.4 Cell line enhanced HUVEC TERT2: 150.2;LHCN-M2: 254.4 +ADGRL4 ELTD1, ETL ENSG00000162618 Adhesion G protein-coupled receptor L4 1 78889764-79006718 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA025229 Supported Renal cancer:1.60e-4 (unfavourable) Expressed in all Mixed adipose tissue: 67.7 Group enriched 5 HUVEC TERT2: 239.6;TIME: 288.6 +LRRIQ3 LRRC44, MGC22773 ENSG00000162620 Leucine rich repeats and IQ motif containing 3 1 74026015-74198187 Predicted intracellular proteins Evidence at protein level HPA030799 Approved Supported Plasma membrane Not detected Tissue enriched 11 testis: 37.1 fallopian tube: 3.5 Mixed +LRRC53 ENSG00000162621 Leucine rich repeat containing 53 1 74469878-74512614 Predicted membrane proteins No evidence HPA054062 Uncertain Not detected Not detected cerebral cortex: 0.5 Not detected +TYW3 C1orf171, FLJ40918 ENSG00000162623 TRNA-yW synthesizing protein 3 homolog 1 74733152-74766678 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029641 Approved Approved Plasma membrane
Cytosol Liver cancer:1.49e-7 (unfavourable) Expressed in all Expressed in all ovary: 32.6 Expressed in all +LHX8 Lhx7 ENSG00000162624 LIM homeobox 8 1 75128434-75161533 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071806 Approved Nucleus
Nucleoli
Cytosol Not detected Tissue enhanced placenta: 1.8;testis: 1.3;tonsil: 1.5 gallbladder,urinary bladder: 1.0 Group enriched 6 SCLC-21H: 30.2;U-266/70: 6.6 +SNX7 ENSG00000162627 Sorting nexin 7 1 98661701-98760500 Predicted intracellular proteins Evidence at protein level HPA037419, HPA054338 Enhanced Approved Nucleoli fibrillar center
Cytosol Liver cancer:9.59e-7 (unfavourable), Colorectal cancer:5.10e-5 (favourable) Expressed in all Mixed smooth muscle: 37.7 Mixed +B3GALT2 beta3Gal-T2 ENSG00000162630 Beta-1,3-galactosyltransferase 2 1 193179045-193186654 Enzymes, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 29.0;gallbladder: 26.0 heart muscle: 14.9 Group enriched 5 AF22: 19.6;ASC TERT1: 6.1;LHCN-M2: 11.4;WM-115: 23.5 +NTNG1 KIAA0976, Lmnt1 ENSG00000162631 Netrin G1 1 107140007-107483458 Predicted secreted proteins Evidence at protein level HPA065954 Supported Plasma membrane Mixed Tissue enhanced cerebral cortex: 8.6 seminal vesicle: 6.7 Cell line enhanced ASC TERT1: 34.3;fHDF/TERT166: 19.6;RPTEC TERT1: 20.8;U-138 MG: 22.6;U-87 MG: 25.0 +FAM102B DKFZp779B126, SYM-3B ENSG00000162636 Family with sequence similarity 102 member B 1 108560089-108644900 Predicted intracellular proteins Evidence at protein level HPA028451 Uncertain Approved Nucleoli
Cytosol Renal cancer:3.47e-6 (unfavourable) Expressed in all Mixed cerebral cortex: 27.9 Mixed +HENMT1 C1orf59, FLJ30525, HEN1 ENSG00000162639 HEN1 methyltransferase homolog 1 1 108648290-108661526 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028464, HPA028497 Uncertain Approved Plasma membrane
Focal adhesion sites Renal cancer:2.48e-5 (unfavourable), Cervical cancer:2.56e-4 (favourable), Colorectal cancer:9.95e-4 (favourable) Expressed in all Tissue enriched 9 testis: 128.3 lymph node: 14.8 Cell line enhanced U-937: 75.4 +AKNAD1 C1orf62, MGC26989 ENSG00000162641 AKNA domain containing 1 1 108815898-108858228 Predicted intracellular proteins Evidence at transcript level HPA030270, HPA030271, HPA030272 Uncertain Tissue enhanced Tissue enriched 63 testis: 6.4 skin: 0.1 Not detected +C1orf52 FLJ44982, gm117 ENSG00000162642 Chromosome 1 open reading frame 52 1 85249953-85259672 Predicted intracellular proteins Evidence at protein level HPA036072, HPA061790 Approved Enhanced Nucleus Renal cancer:1.17e-7 (unfavourable), Liver cancer:5.37e-5 (unfavourable), Prostate cancer:4.93e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 31.8 Expressed in all +WDR63 DIC3, FLJ30067, NYD-SP29 ENSG00000162643 WD repeat domain 63 1 84999147-85133138 Predicted intracellular proteins Evidence at protein level HPA038526 Enhanced Tissue enhanced Tissue enhanced adrenal gland: 28.3;fallopian tube: 23.1;testis: 33.6 parathyroid gland: 6.2 Cell line enhanced ASC TERT1: 5.9;HSkMC: 4.1;hTCEpi: 5.0;LHCN-M2: 5.2 +GBP2 ENSG00000162645 Guanylate binding protein 2 1 89106132-89150456 Predicted intracellular proteins Evidence at protein level HPA042682, CAB045975 Supported Supported Nucleoplasm
Actin filaments
Cytosol Renal cancer:2.14e-10 (unfavourable), Urothelial cancer:1.10e-5 (favourable), Pancreatic cancer:5.73e-5 (unfavourable), Breast cancer:7.57e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 195.5 Cell line enhanced EFO-21: 57.2;HDLM-2: 65.6;RT4: 69.0 +ATXN7L2 FLJ00381, MGC46534 ENSG00000162650 Ataxin 7 like 2 1 109483479-109492804 Predicted intracellular proteins Evidence at protein level HPA029827, HPA054952 Uncertain Approved Nucleoli
Vesicles
Cytosol Renal cancer:1.19e-8 (unfavourable), Endometrial cancer:7.65e-4 (unfavourable) Expressed in all Mixed testis: 4.4 Mixed +GBP4 Mpa2 ENSG00000162654 Guanylate binding protein 4 1 89181148-89198932 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030101, HPA062039 Enhanced Approved Plasma membrane Renal cancer:1.30e-5 (unfavourable), Ovarian cancer:9.29e-5 (favourable) Expressed in all Mixed lung: 46.9 Cell line enhanced CAPAN-2: 10.6;HEL: 11.8;REH: 10.2;RT4: 14.7;U-266/70: 12.3 +ZNF326 FLJ20403, ZAN75, Zfp326, ZIRD ENSG00000162664 Zinc finger protein 326 1 89995112-90035531 Predicted intracellular proteins Evidence at protein level HPA028450, HPA028461, HPA028466 Supported Enhanced Nucleoplasm
Golgi apparatus
Vesicles Urothelial cancer:2.84e-4 (favourable), Breast cancer:9.46e-4 (favourable) Expressed in all Expressed in all bone marrow: 29.5 Expressed in all +HFM1 FLJ36760, FLJ39011, MER3, SEC63D1 ENSG00000162669 HFM1, ATP dependent DNA helicase homolog 1 91260766-91404869 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035036, HPA035557 Supported Golgi apparatus
Vesicles Tissue enhanced Tissue enriched 5 testis: 25.0 ovary: 4.7 Cell line enhanced AF22: 5.1;AN3-CA: 2.6;K-562: 2.6;SCLC-21H: 2.1;SH-SY5Y: 2.3 +BRINP3 DBCCR1L, DBCCR1L1, FAM5C ENSG00000162670 BMP/retinoic acid inducible neural specific 3 1 190097662-190478404 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054693 Uncertain Group enriched Tissue enhanced cerebral cortex: 44.5;small intestine: 19.6 prostate: 10.9 Cell line enriched 6 SCLC-21H: 17.0 +GFI1 GFI-1, GFI1A, ZNF163 ENSG00000162676 Growth factor independent 1 transcriptional repressor 1 92474762-92486876 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB011197 Uncertain Colorectal cancer:5.68e-5 (favourable) Mixed Tissue enhanced bone marrow: 34.8 lymph node: 8.1 Cell line enhanced HL-60: 49.8;HMC-1: 42.0;THP-1: 86.5;U-937: 207.4 +KCNT2 KCa4.2, SLICK, SLO2.1 ENSG00000162687 Potassium sodium-activated channel subfamily T member 2 1 196225779-196609225 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA051218 Uncertain Approved Vesicles Renal cancer:1.67e-5 (unfavourable) Mixed Tissue enhanced ovary: 6.0 cerebral cortex: 3.5 Cell line enhanced HHSteC: 2.7;NTERA-2: 2.6;SCLC-21H: 8.5;SH-SY5Y: 6.9 +AGL ENSG00000162688 Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 1 99850084-99924023 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA028498, HPA054340 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.73e-10 (favourable) Expressed in all Tissue enhanced skeletal muscle: 90.3 parathyroid gland: 35.1 Mixed +VCAM1 CD106 ENSG00000162692 Vascular cell adhesion molecule 1 1 100719742-100739045 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB000154, HPA034796, HPA069867 Enhanced Approved Cell Junctions Head and neck cancer:7.19e-5 (favourable), Cervical cancer:3.82e-4 (favourable) Tissue enriched Tissue enriched 5 spleen: 549.1 lymph node: 109.7 Cell line enhanced HHSteC: 144.7;HSkMC: 83.9;hTEC/SVTERT24-B: 31.1;U-138 MG: 25.9 +EXTL2 ENSG00000162694 Exostosin like glycosyltransferase 2 1 100872372-100895998 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB020716, HPA068921 Approved Approved Nucleus
Cytosol Liver cancer:1.64e-5 (unfavourable) Expressed in all Expressed in all placenta: 34.1 Expressed in all +SLC30A7 ZNT7, ZnTL2 ENSG00000162695 Solute carrier family 30 member 7 1 100896076-100981753 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018034 Uncertain Supported Golgi apparatus Expressed in all Mixed parathyroid gland: 20.9 Expressed in all +ZNF281 ZBP-99 ENSG00000162702 Zinc finger protein 281 1 200404940-200410056 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051228 Uncertain Enhanced Nucleoplasm Renal cancer:2.60e-5 (unfavourable), Cervical cancer:1.16e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 21.5 Expressed in all +ARPC5 ARC16, dJ127C7.3, p16-Arc ENSG00000162704 Actin related protein 2/3 complex subunit 5 1 183620846-183635757 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022013, HPA031972 Approved Approved Vesicles
Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.21e-10 (unfavourable), Liver cancer:3.63e-4 (unfavourable) Expressed in all Expressed in all appendix: 201.3 Expressed in all +CADM3 BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1 ENSG00000162706 Cell adhesion molecule 3 1 159171609-159203313 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA002981, CAB025746 Enhanced Renal cancer:1.03e-5 (unfavourable), Urothelial cancer:5.75e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 278.5;placenta: 113.9 cervix, uterine: 44.7 Group enriched 7 HHSteC: 54.6;HSkMC: 158.9;hTERT-HME1: 91.2;U-2 OS: 34.5;WM-115: 59.5 +NLRP3 AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCU, MWS, NALP3, PYPAF1 ENSG00000162711 NLR family pyrin domain containing 3 1 247416156-247449108 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA012878 Uncertain Mixed Tissue enhanced bone marrow: 34.4 appendix: 14.5 Cell line enhanced NB-4: 9.6;THP-1: 54.1;U-937: 15.5 +ZNF496 MGC15548, ZKSCAN17, ZSCAN49 ENSG00000162714 Zinc finger protein 496 1 247297412-247331846 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055834 Uncertain Golgi apparatus Expressed in all Expressed in all fallopian tube: 24.2 Expressed in all +TRIM58 BIA2 ENSG00000162722 Tripartite motif containing 58 1 247857199-247878205 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023637 Uncertain Mixed Group enriched 6 bone marrow: 16.1;placenta: 6.8;testis: 5.4;thyroid gland: 22.0 prostate: 2.1 Group enriched 5 HAP1: 15.0;HEL: 35.6;K-562: 19.9;PC-3: 34.5;U-2 OS: 31.0;U-937: 8.8;WM-115: 38.8 +SLAMF9 CD2F-10, CD84-H1, SF2001 ENSG00000162723 SLAM family member 9 1 159951492-159954254 Predicted membrane proteins Evidence at transcript level HPA035153 Uncertain Mixed Tissue enhanced testis: 1.1 appendix: 0.6 Cell line enhanced HBEC3-KT: 2.6;HEL: 4.6;PC-3: 1.9;SK-MEL-30: 1.7 +OR2M5 OR2M5P ENSG00000162727 Olfactory receptor family 2 subfamily M member 5 1 248145148-248146086 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +KCNJ9 GIRK3, Kir3.3 ENSG00000162728 Potassium voltage-gated channel subfamily J member 9 1 160081570-160090563 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA070478 Enhanced Tissue enriched Tissue enriched 113 cerebral cortex: 52.3 adrenal gland,testis: 0.4 Not detected +IGSF8 CD316, CD81P3, EWI2, PGRL ENSG00000162729 Immunoglobulin superfamily member 8 1 160091340-160098943 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011917 Uncertain Cervical cancer:7.32e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 107.8 Expressed in all +DDR2 NTRKR3, TKT, TYRO10 ENSG00000162733 Discoidin domain receptor tyrosine kinase 2 1 162631373-162787400 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA070112 Supported Plasma membrane
Actin filaments Renal cancer:1.73e-7 (unfavourable) Expressed in all Mixed adrenal gland: 93.5 Cell line enhanced ASC diff: 203.0;ASC TERT1: 203.2;BJ hTERT+: 181.9 +PEA15 HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED ENSG00000162734 Phosphoprotein enriched in astrocytes 15 1 160205337-160215376 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028356, HPA070820 Enhanced Approved Nucleus
Cytosol Renal cancer:6.53e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1087.0 Expressed in all +PEX19 D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1 ENSG00000162735 Peroxisomal biogenesis factor 19 1 160276812-160286348 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA044837, HPA051966 Supported Enhanced Peroxisomes Renal cancer:2.92e-5 (favourable) Expressed in all Expressed in all adipose tissue: 86.2 Expressed in all +NCSTN APH2, KIAA0253 ENSG00000162736 Nicastrin 1 160343272-160358952 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB021982, HPA054846, HPA070642 Approved Approved Cytosol Renal cancer:7.75e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 143.2 Expressed in all +VANGL2 KIAA1215, LPP1, LTAP, MGC119403, MGC119404, STB1, STBM, STBM1 ENSG00000162738 VANGL planar cell polarity protein 2 1 160400586-160428678 Disease related genes, Predicted membrane proteins Evidence at protein level HPA027043 Uncertain Expressed in all Tissue enhanced skin: 44.6 cerebral cortex: 18.1 Cell line enhanced AF22: 105.2;NTERA-2: 43.1;SH-SY5Y: 30.7 +SLAMF6 CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000 ENSG00000162739 SLAM family member 6 1 160485030-160523262 CD markers, Predicted membrane proteins Evidence at protein level HPA051363, HPA051903 Uncertain Renal cancer:2.09e-6 (unfavourable), Head and neck cancer:7.34e-5 (favourable), Melanoma:1.25e-4 (favourable), Cervical cancer:2.78e-4 (favourable), Breast cancer:9.42e-4 (favourable), Endometrial cancer:9.53e-4 (favourable) Mixed Tissue enhanced lymph node: 70.8;spleen: 43.3;tonsil: 44.6 appendix: 27.2 Cell line enhanced Daudi: 63.2;MOLT-4: 17.4;U-698: 89.3 +OLFML2B DKFZP586L151 ENSG00000162745 Olfactomedin like 2B 1 161983192-162023854 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054136, HPA062739 Approved Approved Cytosol Renal cancer:1.01e-12 (unfavourable), Liver cancer:4.67e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 76.9 placenta: 58.7 Cell line enhanced HSkMC: 82.6;RH-30: 85.9 +FCRLB FCRL2, FCRLM2, FCRLY, FLJ31052, FREB-2 ENSG00000162746 Fc receptor like B 1 161721563-161728143 Predicted secreted proteins Evidence at protein level CAB026139 Uncertain Supported Cytosol Tissue enhanced Tissue enhanced tonsil: 1.6 seminal vesicle: 1.2 Cell line enhanced fHDF/TERT166: 6.8;HMC-1: 6.5 +FCGR3B CD16, CD16b, FCG3, FCGR3 ENSG00000162747 Fc fragment of IgG receptor IIIb 1 161623196-161631963 CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced appendix: 118.1;spleen: 115.2 urinary bladder: 36.3 Not detected +SLC9C2 MGC43026, SLC9A11 ENSG00000162753 Solute carrier family 9 member C2 (putative) 1 173500464-173603094 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Tissue enriched 12 testis: 10.6 fallopian tube: 0.8 Not detected +KLHDC9 KARCA1 ENSG00000162755 Kelch domain containing 9 1 161098361-161100346 Predicted intracellular proteins Evidence at protein level HPA032058, HPA043197 Uncertain Uncertain Nucleoplasm Ovarian cancer:4.20e-6 (favourable) Expressed in all Tissue enhanced testis: 9.5 fallopian tube: 2.3 Cell line enhanced EFO-21: 2.0 +C1orf74 FLJ25078, URLC4 ENSG00000162757 Chromosome 1 open reading frame 74 1 209779208-209784559 Predicted intracellular proteins Evidence at protein level HPA028496 Uncertain Approved Plasma membrane
Cytosol Cervical cancer:8.52e-6 (unfavourable) Expressed in all Mixed lymph node: 5.0 Mixed +LMX1A LMX1, LMX1.1 ENSG00000162761 LIM homeobox transcription factor 1 alpha 1 165201867-165356715 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028051, HPA030088 Approved Nucleoplasm
Golgi apparatus
Vesicles Not detected Tissue enhanced duodenum: 1.0;testis: 2.2 adipose tissue,rectum,small intestine: 0.6 Cell line enriched 11 SCLC-21H: 1.0 +LRRC52 FLJ25811 ENSG00000162763 Leucine rich repeat containing 52 1 165544007-165563961 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 26 testis: 18.6 parathyroid gland: 0.7 Not detected +FLVCR1 AXPC1, FLVCR, MFSD7B, PCA ENSG00000162769 Feline leukemia virus subgroup C cellular receptor 1 1 212858255-212899363 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046646 Approved Approved Cell Junctions Renal cancer:1.06e-5 (unfavourable), Liver cancer:2.52e-5 (unfavourable), Pancreatic cancer:3.50e-4 (favourable) Expressed in all Tissue enhanced small intestine: 21.4 duodenum: 9.8 Expressed in all +FAM71A FLJ32796 ENSG00000162771 Family with sequence similarity 71 member A 1 212624474-212626778 Predicted intracellular proteins Evidence at protein level HPA028462 Enhanced Not detected Tissue enriched 95 testis: 78.3 fallopian tube: 0.8 Not detected +ATF3 ENSG00000162772 Activating transcription factor 3 1 212565334-212620777 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001562 Approved Enhanced Nucleus
Nucleoli Expressed in all Expressed in all smooth muscle: 450.5 Cell line enhanced BEWO: 126.9 +RBM15 OTT, OTT1 ENSG00000162775 RNA binding motif protein 15 1 110338506-110346681 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015201, HPA019824, HPA049642 Supported Enhanced Nucleoplasm Renal cancer:1.37e-4 (unfavourable), Liver cancer:7.61e-4 (unfavourable), Stomach cancer:7.97e-4 (favourable) Expressed in all Mixed bone marrow: 27.9 Expressed in all +DENND2D FLJ22457, RP5-1180E21.2 ENSG00000162777 DENN domain containing 2D 1 111187174-111204535 Predicted intracellular proteins Evidence at protein level HPA043630, HPA048642 Approved Approved Nucleoplasm
Cytosol Urothelial cancer:8.66e-5 (favourable), Cervical cancer:1.67e-4 (favourable), Head and neck cancer:2.70e-4 (favourable) Expressed in all Tissue enhanced lymph node: 110.8 tonsil: 77.1 Cell line enhanced HDLM-2: 60.3;MOLT-4: 132.4;SK-BR-3: 76.3 +AXDND1 C1orf125, FLJ32940 ENSG00000162779 Axonemal dynein light chain domain containing 1 1 179365720-179554735 Predicted intracellular proteins Evidence at protein level HPA071114 Enhanced Not detected Tissue enriched 51 testis: 24.5 epididymis,fallopian tube: 0.4 Not detected +TDRD5 FLJ34823, TUDOR3 ENSG00000162782 Tudor domain containing 5 1 179591613-179691272 Predicted intracellular proteins Evidence at protein level HPA029418 Enhanced Mixed Tissue enriched 5 testis: 42.6 epididymis: 8.0 Cell line enhanced SK-BR-3: 4.4;T-47d: 9.6;U-266/70: 10.9;U-266/84: 9.0 +IER5 ENSG00000162783 Immediate early response 5 1 181088712-181092899 Predicted intracellular proteins Evidence at protein level HPA029894 Uncertain Approved Supported Nucleus
Nucleoli Endometrial cancer:2.42e-7 (favourable), Lung cancer:1.18e-4 (unfavourable), Renal cancer:2.36e-4 (unfavourable) Expressed in all Mixed bone marrow: 31.1 Expressed in all +SNED1 FLJ00133, Snep, SST3 ENSG00000162804 Sushi, nidogen and EGF like domains 1 2 240998838-241095568 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036414, HPA036415 Uncertain Mixed Mixed endometrium: 29.8 Cell line enhanced ASC TERT1: 290.9;HSkMC: 154.1 +BPNT1 ENSG00000162813 3'(2'), 5'-bisphosphate nucleotidase 1 1 220057482-220090462 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048461 Approved Approved Nuclear speckles Renal cancer:6.38e-4 (favourable) Expressed in all Expressed in all small intestine: 48.6 Expressed in all +SPATA17 IQCH ENSG00000162814 Spermatogenesis associated 17 1 217631324-217871696 Predicted intracellular proteins Evidence at protein level HPA030099 Enhanced Approved Nucleus
Nucleoli Mixed Tissue enhanced fallopian tube: 6.5;testis: 18.2 epididymis: 4.1 Cell line enhanced SCLC-21H: 1.5 +C1orf115 FLJ14146 ENSG00000162817 Chromosome 1 open reading frame 115 1 220689845-220699157 Predicted intracellular proteins Evidence at transcript level Ovarian cancer:5.12e-5 (favourable), Endometrial cancer:6.52e-4 (favourable) Expressed in all Mixed small intestine: 110.8 Cell line enhanced Hep G2: 35.3;HUVEC TERT2: 34.6;TIME: 63.7 +BROX C1orf58, FLJ32421 ENSG00000162819 BRO1 domain and CAAX motif containing 1 222712553-222735196 Predicted intracellular proteins Evidence at protein level HPA031445 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all Expressed in all parathyroid gland: 46.7 Expressed in all +NBPF20 ENSG00000162825 Neuroblastoma breakpoint family member 20 1 145289900-145405778 Predicted intracellular proteins Evidence at protein level HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Uncertain Approved Vesicles Not detected Mixed parathyroid gland: 17.1 Mixed +ACP6 ACPL1, LPAP ENSG00000162836 Acid phosphatase 6, lysophosphatidic 1 147629652-147670496 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028560 Uncertain Urothelial cancer:6.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.1 Cell line enhanced RPTEC TERT1: 90.7 +WDR64 FLJ32978 ENSG00000162843 WD repeat domain 64 1 241652278-241802133 Predicted intracellular proteins Evidence at protein level HPA046186 Uncertain Not detected Tissue enriched 10 testis: 5.5 placenta: 0.5 Not detected +KIF26B FLJ10157 ENSG00000162849 Kinesin family member 26B 1 245154985-245709431 Predicted intracellular proteins Evidence at protein level HPA027709, HPA028478, HPA028561, HPA028562 Enhanced Approved Plasma membrane
Microtubules Ovarian cancer:1.24e-4 (unfavourable) Mixed Mixed cerebral cortex: 2.3 Cell line enhanced HSkMC: 8.1;REH: 19.4;SH-SY5Y: 11.8;U-937: 8.1 +TFB2M FLJ22661, FLJ23182, Hkp1 ENSG00000162851 Transcription factor B2, mitochondrial 1 246540560-246566324 Predicted intracellular proteins Evidence at protein level HPA028482, HPA028554, HPA030265 Approved Enhanced Mitochondria Expressed in all Expressed in all adrenal gland: 29.5 Expressed in all +CNST C1orf71, FLJ32001, PPP1R64 ENSG00000162852 Consortin, connexin sorting protein 1 246566444-246668584 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007225, HPA007226 Approved Supported Vesicles Expressed in all Expressed in all cerebral cortex: 26.3 Expressed in all +PPP1R21 CCDC128, FLJ16566, KLRAQ1 ENSG00000162869 Protein phosphatase 1 regulatory subunit 21 2 48440598-48515391 Predicted intracellular proteins Evidence at protein level HPA036791, HPA036792 Approved Approved Vesicles Renal cancer:4.59e-6 (favourable), Endometrial cancer:6.83e-4 (unfavourable), Pancreatic cancer:8.05e-4 (favourable), Thyroid cancer:9.87e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 62.3 Expressed in all +KLHDC8A FLJ10748 ENSG00000162873 Kelch domain containing 8A 1 205336065-205357090 Predicted intracellular proteins Evidence at transcript level Thyroid cancer:8.01e-4 (favourable) Tissue enhanced Tissue enriched 11 ovary: 288.4 adrenal gland: 26.0 Group enriched 7 AF22: 4.1;HAP1: 8.9;NTERA-2: 2.1;SCLC-21H: 10.2 +PM20D1 Cps1, FLJ32569 ENSG00000162877 Peptidase M20 domain containing 1 1 205828022-205850132 Enzymes, Predicted secreted proteins Evidence at transcript level Tissue enriched Tissue enhanced kidney: 6.0;pancreas: 16.6 skin: 3.9 Cell line enriched 10 Karpas-707: 1.3 +PKDCC SgK493, Vlk ENSG00000162878 Protein kinase domain containing, cytoplasmic 2 42048020-42058528 Enzymes, Predicted secreted proteins Evidence at protein level HPA026427, HPA026442, HPA026526 Uncertain Expressed in all Mixed adipose tissue: 27.4 Cell line enhanced AN3-CA: 72.7;ASC diff: 41.5;CACO-2: 78.1;HHSteC: 43.5 +OXER1 GPCR, GPR170, TG1019 ENSG00000162881 Oxoeicosanoid receptor 1 2 42762481-42764261 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA051433 Uncertain Expressed in all Mixed small intestine: 9.2 Cell line enhanced CACO-2: 5.4;Hep G2: 5.1;HMC-1: 5.4;REH: 2.9 +HAAO ENSG00000162882 3-hydroxyanthranilate 3,4-dioxygenase 2 42767089-42792593 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036394, HPA042024 Enhanced Liver cancer:5.77e-4 (favourable) Group enriched Tissue enhanced liver: 152.2 small intestine: 45.5 Cell line enhanced CACO-2: 11.2;Hep G2: 32.9;REH: 9.2 +B3GALNT2 MGC39558 ENSG00000162885 Beta-1,3-N-acetylgalactosaminyltransferase 2 1 235449923-235504481 Disease related genes, Predicted secreted proteins Evidence at protein level HPA012502, HPA050662 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all Mixed smooth muscle: 15.9 Expressed in all +MAPKAPK2 ENSG00000162889 Mitogen-activated protein kinase-activated protein kinase 2 1 206684944-206734283 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level CAB010297, HPA045556, HPA063708, HPA064435 Approved Supported Nucleoplasm
Centrosome Renal cancer:4.58e-6 (unfavourable), Liver cancer:1.93e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 113.0 Expressed in all +IL20 IL-20, IL10D, ZCYTO10 ENSG00000162891 Interleukin 20 1 206865354-206869223 Predicted secreted proteins Evidence at protein level CAB025802 Uncertain Tissue enhanced Tissue enhanced smooth muscle: 1.0 seminal vesicle: 0.8 Cell line enhanced SiHa: 1.9 +IL24 C49A, FISP, IL-24, IL10B, mda-7, Mob-5, ST16 ENSG00000162892 Interleukin 24 1 206897443-206904139 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025972 Uncertain Breast cancer:5.09e-4 (favourable) Mixed Tissue enhanced appendix: 17.3;lymph node: 37.1;spleen: 23.4 urinary bladder: 5.4 Cell line enriched 10 BJ hTERT+: 144.5 +FCMR FAIM3, TOSO ENSG00000162894 Fc fragment of IgM receptor 1 206904386-206923247 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003910 Approved Approved Nucleus
Focal adhesion sites
Cytosol Breast cancer:4.23e-4 (favourable) Expressed in all Tissue enhanced lymph node: 175.8;spleen: 148.0;tonsil: 146.7 appendix: 88.1 Group enriched 5 RPMI-8226: 97.7;U-266/70: 51.8 +PIGR ENSG00000162896 Polymeric immunoglobulin receptor 1 206928518-206946466 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA006154, CAB009454, HPA012012 Enhanced Breast cancer:1.22e-5 (favourable), Renal cancer:5.08e-5 (favourable), Endometrial cancer:2.57e-4 (favourable) Tissue enhanced Tissue enhanced colon: 1688.0;duodenum: 2659.3 rectum: 1335.9 Cell line enriched 7 EFO-21: 33.8 +FCAMR CD351, FCA/MR, FKSG87 ENSG00000162897 Fc fragment of IgA and IgM receptor 1 206957965-206970625 CD markers, Predicted membrane proteins Evidence at protein level HPA056505 Enhanced Tissue enhanced Tissue enhanced kidney: 32.1;lymph node: 14.0;tonsil: 11.3 appendix: 5.2 Not detected +CAPN2 CANPL2, CANPml, mCANP ENSG00000162909 Calpain 2 1 223701593-223776018 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024470 Approved Approved Supported Cytosol Renal cancer:2.19e-4 (favourable), Pancreatic cancer:2.50e-4 (unfavourable), Urothelial cancer:6.21e-4 (unfavourable) Expressed in all Expressed in all lung: 267.0 Mixed +MRPL55 ENSG00000162910 Mitochondrial ribosomal protein L55 1 228106679-228109312 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA027641 Supported Approved Golgi apparatus
Vesicles Renal cancer:1.62e-6 (unfavourable), Ovarian cancer:6.76e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 40.9 Expressed in all +C1orf145 FLJ31994 ENSG00000162913 Chromosome 1 open reading frame 145 1 228203506-228213664 Predicted intracellular proteins Evidence at transcript level HPA046612 Uncertain Mixed Mixed thyroid gland: 1.1 Cell line enhanced HeLa: 1.4;RPTEC TERT1: 1.2 +WDR26 FLJ21016, GID7 ENSG00000162923 WD repeat domain 26 1 224385143-224437033 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028539, HPA061094 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:3.31e-6 (unfavourable) Expressed in all Expressed in all testis: 53.9 Expressed in all +REL c-Rel, I-Rel ENSG00000162924 REL proto-oncogene, NF-kB subunit 2 60881521-60931610 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level CAB004404 Uncertain Mixed Mixed bone marrow: 29.8 Expressed in all +PUS10 CCDC139, FLJ32312 ENSG00000162927 Pseudouridylate synthase 10 2 60940222-61018259 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044736, HPA049582 Approved Approved Nucleoplasm
Nuclear bodies
Mitochondria Expressed in all Mixed thyroid gland: 10.3 Expressed in all +PEX13 ENSG00000162928 Peroxisomal biogenesis factor 13 2 61017225-61051990 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA032141, HPA032142, CAB032689 Enhanced Supported Vesicles Pancreatic cancer:8.07e-5 (unfavourable) Expressed in all Expressed in all testis: 27.5 Expressed in all +KIAA1841 ENSG00000162929 KIAA1841 2 61065871-61138034 Predicted intracellular proteins Evidence at transcript level HPA051240 Approved Approved Nucleus
Nucleoli Expressed in all Mixed prostate: 6.9 Mixed +TRIM17 RBCC, RNF16, terf ENSG00000162931 Tripartite motif containing 17 1 228407940-228416861 Enzymes, Predicted intracellular proteins Evidence at protein level HPA054908 Uncertain Approved Vesicles Breast cancer:1.86e-4 (favourable) Mixed Tissue enhanced testis: 27.8 cerebral cortex: 6.1 Cell line enhanced BEWO: 8.7;SH-SY5Y: 5.0;T-47d: 10.6 +RFTN2 C2orf11, FLJ30574, Raftlin-2 ENSG00000162944 Raftlin family member 2 2 197568224-197676045 Predicted intracellular proteins Evidence at protein level HPA035232 Approved Group enriched Tissue enhanced cerebral cortex: 31.4 ovary: 8.7 Cell line enhanced AF22: 17.0;ASC diff: 8.0;WM-115: 7.5 +DISC1 ENSG00000162946 Disrupted in schizophrenia 1 1 231626815-232041272 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048911 Approved Intermediate filaments Mixed Mixed placenta: 10.5 Mixed +CAPN13 FLJ23523 ENSG00000162949 Calpain 13 2 30722771-30820542 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029496, HPA029497, HPA030034 Uncertain Approved Nucleoplasm Mixed Tissue enhanced rectum: 26.8;small intestine: 32.4;stomach: 26.5 duodenum: 20.8 Cell line enhanced RT4: 7.4;SK-BR-3: 16.4;T-47d: 2.8 +LRRTM1 FLJ32082 ENSG00000162951 Leucine rich repeat transmembrane neuronal 1 2 80288351-80304749 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA062660 Approved Group enriched Tissue enhanced cerebral cortex: 13.3;salivary gland: 4.9 thyroid gland: 2.2 Cell line enhanced SH-SY5Y: 1.4 +MEMO1 C2orf4, CGI-27, MEMO ENSG00000162959 Mediator of cell motility 1 2 31865060-32011230 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042603, HPA057952 Approved Approved Vesicles Mixed Expressed in all testis: 116.1 Expressed in all +DPY30 Cps25, HDPY-30, Saf19 ENSG00000162961 Dpy-30, histone methyltransferase complex regulatory subunit 2 31867809-32039812 Predicted intracellular proteins Evidence at protein level HPA043761 Supported Enhanced Nucleoplasm
Golgi apparatus Renal cancer:4.26e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 138.5 Expressed in all +TYW5 C2orf60, FLJ37953 ENSG00000162971 TRNA-yW synthesizing protein 5 2 199929975-199955736 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028294, HPA045803 Uncertain Approved Nuclear bodies Expressed in all Mixed appendix: 1.6 Mixed +MAIP1 C2orf47, DKFZp666A212, FLJ22555 ENSG00000162972 Matrix AAA peptidase interacting protein 1 2 199955317-200008540 Predicted intracellular proteins Evidence at protein level HPA064013, HPA072231 Approved Approved Mitochondria Melanoma:1.87e-4 (unfavourable), Endometrial cancer:2.14e-4 (unfavourable), Head and neck cancer:3.81e-4 (unfavourable) Expressed in all Expressed in all kidney: 31.9 Expressed in all +KCNF1 IK8, KCNF, kH1, Kv5.1 ENSG00000162975 Potassium voltage-gated channel modifier subfamily F member 1 2 10911937-10914225 Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA014738, HPA062278 Enhanced Approved Golgi apparatus Tissue enriched Tissue enriched 32 cerebral cortex: 37.5 endometrium: 1.1 Cell line enhanced A549: 12.9;MCF7: 3.9;T-47d: 5.7 +PQLC3 C2orf22, MGC33602 ENSG00000162976 PQ loop repeat containing 3 2 11155198-11178874 Predicted membrane proteins Evidence at protein level HPA061607 Approved Cytosol Expressed in all Expressed in all cervix, uterine,epididymis: 54.6 Mixed +ARL5A ARL5 ENSG00000162980 ADP ribosylation factor like GTPase 5A 2 151788984-151828492 Predicted intracellular proteins Evidence at protein level HPA027002 Approved Expressed in all Expressed in all thyroid gland: 48.9 Expressed in all +FAM84A FLJ35392, NSE1 ENSG00000162981 Family with sequence similarity 84 member A 2 14632686-14650814 Predicted intracellular proteins Evidence at protein level HPA047703 Uncertain Approved Nucleus Mixed Mixed colon: 40.3 Cell line enhanced hTCEpi: 13.1;RT4: 39.2 +KCNJ3 GIRK1, KGA, Kir3.1 ENSG00000162989 Potassium voltage-gated channel subfamily J member 3 2 154698299-154858352 Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA024231 Uncertain Group enriched Tissue enhanced cerebral cortex: 25.4;parathyroid gland: 39.8 seminal vesicle: 14.1 Cell line enhanced BJ: 1.2 +NEUROD1 BETA2, BHF-1, bHLHa3, MODY6, NEUROD ENSG00000162992 Neuronal differentiation 1 2 181673088-181680876 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003278, CAB022450 Approved Glioma:6.83e-5 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 5.9;duodenum: 6.0;small intestine: 4.4;stomach: 4.9 pancreas: 1.8 Cell line enriched 79 SCLC-21H: 331.4 +CLHC1 C2orf63, FLJ31438 ENSG00000162994 Clathrin heavy chain linker domain containing 1 2 55174791-55232563 Predicted intracellular proteins Evidence at protein level HPA045418, HPA053557 Uncertain Approved Nucleoli fibrillar center
Centrosome Urothelial cancer:2.15e-4 (favourable) Mixed Tissue enhanced testis: 23.1 endometrium: 6.8 Mixed +FRZB FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3 ENSG00000162998 Frizzled-related protein 2 182833275-182867162 Disease related genes, Predicted secreted proteins Evidence at protein level Renal cancer:8.97e-6 (unfavourable) Expressed in all Tissue enhanced spleen: 101.2 gallbladder: 50.3 Cell line enhanced AF22: 16.2;ASC diff: 5.3;NTERA-2: 6.7;SH-SY5Y: 6.0 +DUSP19 DUSP17, SKRP1 ENSG00000162999 Dual specificity phosphatase 19 2 183078559-183100005 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021501 Approved Approved Nucleoplasm Mixed Mixed testis: 5.5 Mixed +CFAP36 BARTL1, CCDC104, MGC15407 ENSG00000163001 Cilia and flagella associated protein 36 2 55519604-55545879 Predicted intracellular proteins Evidence at protein level HPA008994, HPA017061 Approved Expressed in all Expressed in all testis: 239.2 Expressed in all +NUP35 MP44 ENSG00000163002 Nucleoporin 35 2 183117513-183161680 Predicted intracellular proteins, Transporters Evidence at protein level HPA018401, HPA018410, HPA018441 Enhanced Supported Nucleoplasm
Nuclear membrane
Plasma membrane Ovarian cancer:3.45e-4 (favourable), Liver cancer:5.02e-4 (unfavourable) Expressed in all Expressed in all testis: 44.4 Expressed in all +CCDC138 FLJ32745 ENSG00000163006 Coiled-coil domain containing 138 2 108786757-108885477 Predicted intracellular proteins Evidence at protein level HPA049899, HPA054223 Enhanced Approved Nucleus
Cytosol Mixed Tissue enhanced testis: 19.6 fallopian tube: 6.9 Expressed in all +ZSWIM2 MGC33890, ZZZ2 ENSG00000163012 Zinc finger SWIM-type containing 2 2 186827835-186849208 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 133 testis: 18.4 cerebral cortex,placenta: 0.1 Not detected +FBXO41 Fbx41, KIAA1940 ENSG00000163013 F-box protein 41 2 73254682-73284431 Predicted intracellular proteins Evidence at protein level HPA055246, HPA058386 Approved Nucleus
Plasma membrane
Cytosol Renal cancer:1.08e-5 (unfavourable), Endometrial cancer:5.76e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 38.3 parathyroid gland: 11.1 Cell line enhanced Daudi: 33.9 +ACTG2 ACTA3, ACTL3, ACTSG ENSG00000163017 Actin, gamma 2, smooth muscle, enteric 2 73892314-73919865 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041264, HPA041271 Supported Renal cancer:3.95e-7 (unfavourable) Expressed in all Tissue enhanced seminal vesicle: 8158.9;smooth muscle: 11634.7 prostate: 3438.5 Cell line enhanced BEWO: 57.4;BJ hTERT+ SV40 Large T+: 177.9;U-251 MG: 176.7 +WDCP C2orf44, FLJ21945 ENSG00000163026 WD repeat and coiled coil containing 2 24029340-24049575 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041054 Approved Approved Nucleoli
Cytosol Liver cancer:5.14e-8 (unfavourable), Endometrial cancer:6.53e-4 (unfavourable) Expressed in all Mixed testis: 9.3 Expressed in all +SMC6 FLJ22116, SMC6L1 ENSG00000163029 Structural maintenance of chromosomes 6 2 17663812-17800242 Predicted intracellular proteins Evidence at protein level HPA035057, CAB037186, HPA042733 Uncertain Supported Nucleoplasm Renal cancer:3.15e-4 (unfavourable) Expressed in all Expressed in all testis: 64.7 Expressed in all +VSNL1 HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1 ENSG00000163032 Visinin like 1 2 17539126-17657018 Predicted intracellular proteins Evidence at protein level HPA053808 Glioma:9.39e-4 (unfavourable) Mixed Tissue enriched 14 cerebral cortex: 624.2 esophagus: 44.0 Cell line enhanced HaCaT: 107.2;Hep G2: 85.4 +CCDC74A FLJ40345 ENSG00000163040 Coiled-coil domain containing 74A 2 131527675-131533666 Predicted intracellular proteins Evidence at transcript level HPA060727 Uncertain Vesicles Renal cancer:1.70e-7 (unfavourable), Glioma:1.82e-4 (unfavourable), Testis cancer:4.92e-4 (favourable), Breast cancer:5.11e-4 (favourable) Mixed Tissue enhanced fallopian tube: 55.2;testis: 79.2 parathyroid gland: 27.2 Cell line enhanced NTERA-2: 28.4;SCLC-21H: 27.2 +H3F3A H3.3A, H3F3 ENSG00000163041 H3 histone family member 3A 1 226061851-226072001 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB011481, CAB037178, HPA042570 Supported Supported Nucleoplasm Renal cancer:1.21e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 1215.4 Expressed in all +ANKRD30BL ANKRD30BP3, NCRNA00164 ENSG00000163046 Ankyrin repeat domain 30B like 2 132147591-132257969 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 31 testis: 3.0 appendix: 0.1 Not detected +COQ8A ADCK3, CABC1, COQ8, SCAR9 ENSG00000163050 Coenzyme Q8A 1 226897536-226987545 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA061662 Supported Mitochondria Expressed in all Tissue enriched 6 skeletal muscle: 401.8 adrenal gland: 68.1 Cell line enhanced HEK 293: 75.6 +SLC16A14 FLJ30794, MCT14 ENSG00000163053 Solute carrier family 16 member 14 2 230034974-230068999 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA040518 Uncertain Approved Endoplasmic reticulum Mixed Mixed parathyroid gland: 14.7 Cell line enhanced HL-60: 16.9;Karpas-707: 10.1;REH: 16.6;RPMI-8226: 11.3 +TEKT4 MGC27019 ENSG00000163060 Tektin 4 2 94871433-94876829 Predicted intracellular proteins Evidence at protein level HPA048600, HPA053929 Uncertain Uncertain Intermediate filaments Endometrial cancer:1.29e-4 (favourable) Tissue enriched Group enriched 15 fallopian tube: 4.2;testis: 5.2 lung: 0.3 Not detected +EN1 ENSG00000163064 Engrailed homeobox 1 2 118842171-118847678 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB014884, HPA073141 Approved Supported Nucleus
Nucleoli Tissue enhanced Group enriched 13 adipose tissue: 1.3;breast: 1.0;lymph node: 1.9;skeletal muscle: 4.7;skin: 2.2 testis: 0.1 Cell line enhanced ASC diff: 10.8;fHDF/TERT166: 10.2;HSkMC: 9.7;PC-3: 7.1;U-138 MG: 9.6;U-2197: 10.2 +SGCB A3b, LGMD2E, SGC ENSG00000163069 Sarcoglycan beta 4 52020706-52038482 Disease related genes, Predicted membrane proteins Evidence at protein level HPA011422, HPA058656 Enhanced Approved Cytosol Renal cancer:5.53e-6 (favourable), Urothelial cancer:7.61e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 75.4 Mixed +SPATA18 FLJ32906 ENSG00000163071 Spermatogenesis associated 18 4 52051331-52097292 Predicted intracellular proteins Evidence at protein level HPA036854, HPA036855 Enhanced Renal cancer:3.73e-9 (favourable), Endometrial cancer:1.32e-5 (favourable) Expressed in all Tissue enhanced fallopian tube: 109.4;testis: 42.6 cervix, uterine: 16.2 Cell line enhanced ASC TERT1: 22.1;BEWO: 23.6;HSkMC: 21.4;hTCEpi: 20.9 +NOSTRIN MGC20702 ENSG00000163072 Nitric oxide synthase trafficking 2 168786539-168865514 Predicted intracellular proteins Evidence at protein level HPA044384 Approved Supported Nuclear speckles Mixed Mixed placenta: 36.4 Cell line enhanced BEWO: 9.8;HEL: 35.7;K-562: 27.4 +CFAP221 FAP221, PCDP1 ENSG00000163075 Cilia and flagella associated protein 221 2 119544432-119662251 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced fallopian tube: 41.9;testis: 44.7 lung: 11.5 Cell line enhanced RPTEC TERT1: 4.1 +CCDC140 FLJ32447 ENSG00000163081 Coiled-coil domain containing 140 2 222298147-222305217 Predicted intracellular proteins Evidence at transcript level HPA042500, HPA048166 Uncertain Tissue enriched Not detected skin: 0.3 Not detected +SGPP2 FLJ39004, SPP2 ENSG00000163082 Sphingosine-1-phosphate phosphatase 2 2 222424517-222560948 Predicted membrane proteins Evidence at transcript level Renal cancer:1.28e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 59.2 thyroid gland: 33.7 Cell line enhanced CAPAN-2: 13.9;EFO-21: 12.7;hTCEpi: 31.0;RPTEC TERT1: 32.2;SCLC-21H: 20.4 +INHBB ENSG00000163083 Inhibin beta B subunit 2 120346143-120351808 Cancer-related genes, Predicted secreted proteins Evidence at protein level Thyroid cancer:1.02e-4 (favourable), Colorectal cancer:1.44e-4 (unfavourable), Renal cancer:3.02e-4 (unfavourable) Expressed in all Tissue enhanced testis: 27.1 adipose tissue: 24.9 Cell line enhanced A549: 42.9;ASC diff: 43.3;MCF7: 44.4;PC-3: 85.1;SK-BR-3: 122.2 +XIRP2 CMYA3 ENSG00000163092 Xin actin binding repeat containing 2 2 166888487-167259753 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034813, HPA074599 Uncertain Approved Nucleoplasm
Plasma membrane Tissue enriched Group enriched 22 heart muscle: 84.0;skeletal muscle: 301.6 prostate: 8.8 Cell line enhanced AN3-CA: 1.4;HUVEC TERT2: 3.5;U-2197: 2.7 +BBS5 DKFZp762I194 ENSG00000163093 Bardet-Biedl syndrome 5 2 169479178-169506655 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046125 Uncertain Pancreatic cancer:1.02e-4 (favourable) Mixed Mixed testis: 12.6 Mixed +BIRC8 hILP2, ILP-2 ENSG00000163098 Baculoviral IAP repeat containing 8 19 53289601-53291626 Plasma proteins, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 179 testis: 17.8 all non-specific tissues: 0.0 Not detected +SMARCAD1 DKFZP762K2015, ETL1, KIAA1122 ENSG00000163104 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 4 94207611-94291292 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA016737 Approved Enhanced Nucleoplasm Liver cancer:3.22e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.6 Expressed in all +HPGDS GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS ENSG00000163106 Hematopoietic prostaglandin D synthase 4 94298535-94342876 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024035 Enhanced Mixed Tissue enhanced placenta: 28.1 lung: 14.5 Group enriched 9 HEL: 43.7;HMC-1: 12.2 +PDLIM5 Enh, LIM ENSG00000163110 PDZ and LIM domain 5 4 94451857-94668227 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013511, HPA016740, HPA020026 Approved Supported Nucleoplasm
Plasma membrane
Focal adhesion sites Tissue enriched Expressed in all heart muscle: 424.8 Expressed in all +PDHA2 PDHAL ENSG00000163114 Pyruvate dehydrogenase (lipoamide) alpha 2 4 95840019-95841474 Citric acid cycle related proteins, Enzymes, Predicted intracellular proteins Evidence at protein level HPA047487, HPA047864, HPA063053 Approved Supported Mitochondria Not detected Tissue enriched 1010 testis: 101.0 all non-specific tissues: 0.0 Not detected +STPG2 C4orf37, MGC46496 ENSG00000163116 Sperm tail PG-rich repeat containing 2 4 97184093-98143240 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced testis: 3.9 thyroid gland: 0.9 Not detected +NEURL3 Lincr, LOC93082 ENSG00000163121 Neuralized E3 ubiquitin protein ligase 3 2 96497643-96508109 Enzymes, Predicted intracellular proteins Evidence at transcript level Liver cancer:6.46e-4 (unfavourable) Mixed Tissue enhanced salivary gland: 13.9 pancreas: 4.2 Cell line enhanced BEWO: 3.6;CAPAN-2: 13.6;RPMI-8226: 6.9;RT4: 3.7 +RPRD2 FLJ32145, HSPC099, KIAA0460 ENSG00000163125 Regulation of nuclear pre-mRNA domain containing 2 1 150363091-150476566 Predicted intracellular proteins Evidence at protein level HPA061693 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 38.5 Expressed in all +ANKRD23 DARP, FLJ32449, MARP3 ENSG00000163126 Ankyrin repeat domain 23 2 96824526-96857934 Predicted intracellular proteins Evidence at protein level HPA036201 Approved Supported Nucleoplasm
Actin filaments Not detected Tissue enriched 64 skeletal muscle: 495.5 prostate: 7.7 Cell line enriched 8 Karpas-707: 27.1 +CTSS ENSG00000163131 Cathepsin S 1 150730196-150765957 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000460, HPA002988 Supported Approved Vesicles Expressed in all Expressed in all spleen: 374.8 Cell line enhanced HMC-1: 238.0;U-698: 410.8 +MSX1 HOX7, HYD1, OFC5 ENSG00000163132 Msh homeobox 1 4 4859666-4863936 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026198, HPA063895, HPA073604 Enhanced Supported Nucleoplasm Endometrial cancer:1.64e-7 (favourable), Renal cancer:1.18e-5 (unfavourable) Tissue enriched Group enriched 6 cervix, uterine: 61.1;endometrium: 23.7 adipose tissue: 6.6 Cell line enhanced CACO-2: 39.5 +PACRGL C4orf28, MGC29898 ENSG00000163138 PARK2 coregulated like 4 20696282-20752907 Predicted intracellular proteins Evidence at protein level HPA054666 Approved Nucleoplasm
Vesicles Urothelial cancer:4.85e-4 (favourable) Expressed in all Expressed in all testis: 60.3 Expressed in all +BNIPL BNIP-S, BNIP-Salpha, BNIP-Sbeta, BNIPl-1, BNIPL-2, PP753 ENSG00000163141 BCL2 interacting protein like 1 151036570-151047600 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019946 Approved Cytosol Thyroid cancer:4.32e-4 (favourable), Endometrial cancer:6.50e-4 (unfavourable) Mixed Group enriched 7 esophagus: 88.9;skin: 227.0 breast: 21.6 Cell line enriched 14 T-47d: 44.3 +C1QTNF7 CTRP7 ENSG00000163145 C1q and tumor necrosis factor related protein 7 4 15339818-15446166 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB007055, HPA051797, HPA055392 Uncertain Approved Vesicles Mixed Mixed cervix, uterine: 36.4 Cell line enhanced ASC diff: 3.0;ASC TERT1: 2.1;HSkMC: 1.2 +TNFAIP8L2 FLJ23467 ENSG00000163154 TNF alpha induced protein 8 like 2 1 151156629-151159749 Predicted intracellular proteins Evidence at protein level HPA062742 Uncertain Vesicles Renal cancer:3.53e-7 (unfavourable), Melanoma:3.64e-4 (favourable) Expressed in all Tissue enhanced lymph node: 34.7;spleen: 39.1 appendix: 25.8 Group enriched 6 HEL: 26.1;HL-60: 13.6;HMC-1: 38.0;NB-4: 15.6;THP-1: 62.9;U-937: 28.8 +LYSMD1 MGC35223, RP11-68I18.5, SB145 ENSG00000163155 LysM domain containing 1 1 151159748-151165948 Predicted intracellular proteins Evidence at protein level HPA028055, HPA064537 Uncertain Enhanced Nucleus Expressed in all Mixed ovary: 13.3 Expressed in all +SCNM1 MGC3180 ENSG00000163156 Sodium channel modifier 1 1 151156664-151170297 Predicted intracellular proteins Evidence at protein level HPA052439, HPA054324 Uncertain Approved Nucleus Renal cancer:2.17e-13 (unfavourable), Ovarian cancer:1.23e-4 (favourable) Expressed in all Expressed in all lymph node: 45.2 Expressed in all +TMOD4 Sk-Tmod ENSG00000163157 Tropomodulin 4 1 151169986-151176284 Predicted intracellular proteins Evidence at protein level HPA028203 Enhanced Not detected Tissue enriched 29 skeletal muscle: 378.9 prostate: 13.0 Mixed +VPS72 Swc2, TCFL1, YL-1, YL1 ENSG00000163159 Vacuolar protein sorting 72 homolog 1 151169987-151195321 Predicted intracellular proteins Evidence at protein level HPA065709 Supported Nuclear speckles Liver cancer:4.41e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 43.1 Expressed in all +ERCC3 BTF2, GTF2H, RAD25, TFIIH, XPB ENSG00000163161 ERCC excision repair 3, TFIIH core complex helicase subunit 2 127257290-127294176 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB037153, HPA046077 Approved Enhanced Nucleoplasm Liver cancer:1.62e-7 (unfavourable), Renal cancer:4.30e-6 (unfavourable) Expressed in all Expressed in all testis: 55.1 Expressed in all +RNF149 FLJ90504 ENSG00000163162 Ring finger protein 149 2 101271219-101308701 Enzymes, Predicted membrane proteins Evidence at protein level HPA011424 Approved Approved Vesicles
Plasma membrane Renal cancer:2.04e-8 (unfavourable), Urothelial cancer:2.91e-4 (favourable) Expressed in all Expressed in all appendix: 67.8 Mixed +IWS1 DKFZp761G0123, FLJ10006, FLJ14655, FLJ32319 ENSG00000163166 IWS1, SUPT6H interacting protein 2 127436207-127526886 Predicted intracellular proteins Evidence at protein level HPA035719, HPA061866 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 44.2 Expressed in all +BOLA3 ENSG00000163170 BolA family member 3 2 74135398-74147994 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053162 Uncertain Renal cancer:9.90e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 49.5 Expressed in all +CDC42EP3 BORG2, CEP3, UB1 ENSG00000163171 CDC42 effector protein 3 2 37641882-37738468 Predicted intracellular proteins Evidence at protein level HPA034986, HPA061792 Approved Supported Plasma membrane
Actin filaments Expressed in all Expressed in all prostate: 153.3 Cell line enhanced LHCN-M2: 504.9 +S100A11 S100C ENSG00000163191 S100 calcium binding protein A11 1 152032506-152047907 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034320, HPA042745 Enhanced Renal cancer:3.24e-6 (unfavourable), Liver cancer:3.64e-5 (unfavourable) Expressed in all Expressed in all esophagus: 2721.4 Expressed in all +LCE3D LEP16, SPRL6A, SPRL6B ENSG00000163202 Late cornified envelope 3D 1 152579381-152580504 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enhanced skin: 26.5;tonsil: 79.8 esophagus: 11.6 Group enriched 5 hTCEpi: 3.2;hTERT-HME1: 3.1 +SMCP MCSP ENSG00000163206 Sperm mitochondria associated cysteine rich protein 1 152878317-152885047 Predicted intracellular proteins Evidence at protein level HPA035105 Supported Tissue enhanced Tissue enriched 480 testis: 797.7 cerebral cortex: 1.6 Not detected +IVL ENSG00000163207 Involucrin 1 152908545-152911886 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002243, HPA055211 Enhanced Supported Nuclear bodies
Centrosome
Cytosol Group enriched Group enriched 7 esophagus: 308.3;skin: 131.2 tonsil: 32.9 Group enriched 24 HaCaT: 256.2;RT4: 61.2;SK-BR-3: 64.8 +SPRR3 ENSG00000163209 Small proline rich protein 3 1 153001747-153003856 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA044467 Enhanced Pancreatic cancer:6.27e-5 (unfavourable) Tissue enhanced Tissue enriched 10 esophagus: 22075.5 tonsil: 2218.1 Cell line enhanced CAPAN-2: 5.2;hTCEpi: 6.9;RT4: 10.0 +DHX57 DDX57 ENSG00000163214 DExH-box helicase 57 2 38797729-38875934 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036160 Uncertain Approved Nucleoli
Intermediate filaments
Microtubules
Cytosol Liver cancer:3.32e-6 (unfavourable) Expressed in all Mixed testis: 30.8 Expressed in all +SPRR2D ENSG00000163216 Small proline rich protein 2D 1 153039725-153041931 Predicted intracellular proteins Evidence at protein level Urothelial cancer:1.62e-4 (unfavourable) Group enriched Tissue enriched 7 esophagus: 2272.9 tonsil: 348.0 Group enriched 10 hTCEpi: 29.4;hTERT-HME1: 27.2;SK-MEL-30: 14.0;U-87 MG: 6.4 +BMP10 ENSG00000163217 Bone morphogenetic protein 10 2 68865481-68871517 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 91 heart muscle: 327.8 liver: 3.5 Not detected +PGLYRP4 PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67 ENSG00000163218 Peptidoglycan recognition protein 4 1 153330120-153348840 Predicted secreted proteins Evidence at protein level CAB025879 Approved Vesicles
Plasma membrane Group enriched Group enriched 6 esophagus: 5.8;skin: 18.2 tonsil: 2.1 Cell line enhanced HaCaT: 3.4;HDLM-2: 2.4;Karpas-707: 1.4 +ARHGAP25 KIAA0053 ENSG00000163219 Rho GTPase activating protein 25 2 68679601-68826833 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035346, HPA061395 Enhanced Approved Nucleoplasm
Vesicles Renal cancer:1.93e-4 (unfavourable), Cervical cancer:7.72e-4 (favourable) Expressed in all Tissue enhanced spleen: 89.6 lymph node: 81.2 Cell line enhanced HEL: 59.7;HMC-1: 225.1 +S100A9 60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14 ENSG00000163220 S100 calcium binding protein A9 1 153357854-153361027 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004193, CAB009441 Enhanced Supported Nucleoplasm
Cell Junctions
Cytosol Liver cancer:1.13e-6 (unfavourable), Renal cancer:8.10e-4 (unfavourable) Expressed in all Group enriched 6 bone marrow: 20959.3;esophagus: 24239.1 tonsil: 3911.6 Cell line enriched 5 SK-BR-3: 1782.7 +S100A12 CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6 ENSG00000163221 S100 calcium binding protein A12 1 153373706-153375649 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002881, CAB025872 Enhanced Renal cancer:5.03e-4 (unfavourable) Tissue enhanced Tissue enriched 19 bone marrow: 2045.4 spleen: 107.1 Cell line enhanced hTCEpi: 1.6;THP-1: 1.0 +TGFA ENSG00000163235 Transforming growth factor alpha 2 70447280-70554193 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA042297 Approved Approved Vesicles Pancreatic cancer:1.20e-5 (unfavourable), Thyroid cancer:1.52e-4 (favourable) Expressed in all Mixed esophagus: 27.2 Cell line enhanced A-431: 58.1;CAPAN-2: 69.9;HBEC3-KT: 50.1;RPTEC TERT1: 52.1;U-87 MG: 63.0 +TDRD10 DKFZp434M202 ENSG00000163239 Tudor domain containing 10 1 154502219-154548147 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level HPA054327 Approved Vesicles Thyroid cancer:8.04e-5 (favourable) Tissue enhanced Tissue enriched 12 testis: 77.3 lung: 6.3 Cell line enhanced HUVEC TERT2: 2.5;TIME: 1.3 +CCNYL1 FLJ40432 ENSG00000163249 Cyclin Y like 1 2 207711540-207761839 Predicted intracellular proteins Evidence at protein level HPA046825 Approved Approved Plasma membrane Expressed in all Expressed in all testis: 30.4 Expressed in all +FZD5 C2orf31, DKFZP434E2135, HFZ5 ENSG00000163251 Frizzled class receptor 5 2 207762586-207769563 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA052361 Approved Expressed in all Mixed duodenum: 19.6 Cell line enhanced BEWO: 105.1;NTERA-2: 32.1 +CRYGC CRYG3 ENSG00000163254 Crystallin gamma C 2 208128137-208129830 Disease related genes, Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 9 testis: 2.6 epididymis: 0.3 Not detected +DCAF16 C4orf30, FLJ20280 ENSG00000163257 DDB1 and CUL4 associated factor 16 4 17800655-17810758 Predicted intracellular proteins Evidence at protein level HPA042487 Uncertain Approved Plasma membrane
Cytosol Lung cancer:5.78e-4 (favourable), Liver cancer:6.40e-4 (unfavourable), Urothelial cancer:7.67e-4 (favourable) Expressed in all Expressed in all endometrium: 23.0 Expressed in all +C1orf189 ENSG00000163263 Chromosome 1 open reading frame 189 1 154199372-154206333 Predicted intracellular proteins Evidence at protein level HPA045779 Uncertain Tissue enhanced Group enriched 16 fallopian tube: 127.5;testis: 69.2 cervix, uterine: 6.0 Mixed +NPPC CNP ENSG00000163273 Natriuretic peptide C 2 231921820-231926403 Predicted secreted proteins, Transporters Evidence at protein level HPA035362 Uncertain Mixed Tissue enhanced prostate: 6.9 cerebral cortex: 3.0 Cell line enhanced HEK 293: 7.7;NTERA-2: 3.9;SCLC-21H: 6.4;SK-MEL-30: 18.9 +GNPDA2 SB52 ENSG00000163281 Glucosamine-6-phosphate deaminase 2 4 44682200-44726595 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000499, HPA046891 Uncertain Approved Golgi apparatus
Vesicles Expressed in all Expressed in all thyroid gland: 32.4 Mixed +ALPP ENSG00000163283 Alkaline phosphatase, placental 2 232378534-232382889 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB026327, HPA038764, HPA038765, HPA051699 Enhanced Approved Plasma membrane Pancreatic cancer:4.33e-4 (unfavourable) Tissue enhanced Group enriched 14 cervix, uterine: 25.5;placenta: 45.5 fallopian tube: 2.5 Group enriched 6 HaCaT: 311.4;SiHa: 103.4 +GABRG1 ENSG00000163285 Gamma-aminobutyric acid type A receptor gamma1 subunit 4 46035769-46124081 FDA approved drug targets, Predicted membrane proteins Evidence at transcript level HPA035622 Approved Tissue enriched Tissue enriched 17 cerebral cortex: 26.0 ovary: 1.5 Cell line enhanced U-266/70: 1.1 +ALPPL2 ENSG00000163286 Alkaline phosphatase, placental like 2 2 232406843-232410714 Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB020698, HPA038764, HPA038765, HPA051699 Supported Approved Plasma membrane Tissue enhanced Tissue enhanced fallopian tube: 1.5 lung: 0.7 Group enriched 29 BEWO: 6.5;CAPAN-2: 29.9;HaCaT: 22.2 +GABRB1 ENSG00000163288 Gamma-aminobutyric acid type A receptor beta1 subunit 4 46993723-47426444 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051297 Uncertain Tissue enhanced Tissue enriched 12 cerebral cortex: 19.7 heart muscle: 1.5 Cell line enhanced REH: 1.4;U-87 MG: 2.4 +PAQR3 ENSG00000163291 Progestin and adipoQ receptor family member 3 4 78887127-78939438 Predicted membrane proteins Evidence at protein level HPA058453 Uncertain Expressed in all Not detected testis: 0.7 Not detected +NIPAL1 DKFZp686A06115, NPAL1 ENSG00000163293 NIPA like domain containing 1 4 47914142-48040173 Predicted membrane proteins Evidence at transcript level HPA036765 Uncertain Approved Golgi apparatus Mixed Tissue enhanced esophagus: 24.0;skin: 30.8 rectum: 14.6 Cell line enhanced A-431: 11.6;HaCaT: 13.6;RT4: 14.3 +ALPI ENSG00000163295 Alkaline phosphatase, intestinal 2 232456123-232460032 Enzymes, Predicted secreted proteins Evidence at protein level HPA038764, HPA038765, HPA051699 Supported Approved Plasma membrane Tissue enhanced Group enriched 31 duodenum: 203.2;small intestine: 212.1 colon: 6.6 Cell line enriched 10 CACO-2: 5.9 +ANTXR2 CMG-2, CMG2, FLJ31074 ENSG00000163297 Anthrax toxin receptor 2 4 79901149-80125454 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Renal cancer:3.34e-6 (unfavourable), Pancreatic cancer:1.33e-4 (unfavourable) Expressed in all Mixed prostate: 139.5 Cell line enhanced LHCN-M2: 147.2 +HELQ Hel308 ENSG00000163312 Helicase, POLQ-like 4 83407343-83455856 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036852, HPA036853 Approved Approved Nucleoplasm
Nuclear speckles Renal cancer:2.76e-4 (favourable), Pancreatic cancer:9.07e-4 (favourable) Expressed in all Mixed adrenal gland: 11.9 Expressed in all +MRPS18C CGI-134, FLJ11146, FLJ22967, MRPS18-1 ENSG00000163319 Mitochondrial ribosomal protein S18C 4 83455932-83469735 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050404 Approved Renal cancer:2.90e-5 (favourable) Expressed in all Expressed in all fallopian tube: 39.7 Expressed in all +CGGBP1 CGGBP, p20-CGGBP ENSG00000163320 CGG triplet repeat binding protein 1 3 88051944-88149885 Predicted intracellular proteins Evidence at protein level HPA035568, HPA037017 Supported Enhanced Nucleus Urothelial cancer:7.79e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 93.6 Expressed in all +FAM175A ABRA1, ABRAXAS, CCDC98, FLJ13614 ENSG00000163322 Family with sequence similarity 175 member A 4 83459517-83523348 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037654 Uncertain Supported Nuclear bodies Renal cancer:1.53e-4 (favourable) Mixed Mixed testis: 22.1 Expressed in all +GPR155 DEP.7, DEPDC3, FLJ31819, PGR22 ENSG00000163328 G protein-coupled receptor 155 2 174431571-174487094 Predicted membrane proteins Evidence at protein level HPA036159, HPA057384 Approved Approved Nuclear bodies
Cytosol Expressed in all Expressed in all stomach: 45.4 Cell line enhanced U-266/70: 11.3;WM-115: 9.8 +DAPL1 ENSG00000163331 Death associated protein like 1 2 158795317-158862781 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046937, HPA058635 Enhanced Approved Nucleoplasm
Nuclear bodies
Microtubules Cervical cancer:8.43e-4 (favourable) Group enriched Tissue enhanced epididymis: 238.2;esophagus: 243.7;skin: 219.0 fallopian tube: 128.4 Group enriched 5 HaCaT: 3.5;hTCEpi: 16.6;SCLC-21H: 6.9;U-87 MG: 8.2 +PMVK HUMPMKI, PMK, PMKA ENSG00000163344 Phosphomevalonate kinase 1 154924734-154936991 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029900 Approved Renal cancer:4.96e-4 (favourable), Ovarian cancer:9.70e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.5 Expressed in all +PBXIP1 HPIP ENSG00000163346 PBX homeobox interacting protein 1 1 154944076-154956123 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006949 Approved Approved Vesicles
Cytosol Renal cancer:9.22e-6 (favourable), Pancreatic cancer:2.64e-4 (favourable), Colorectal cancer:2.73e-4 (unfavourable), Head and neck cancer:7.19e-4 (favourable), Lung cancer:8.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 138.8 Cell line enriched 7 Karpas-707: 788.8 +CLDN1 ILVASC, SEMP1 ENSG00000163347 Claudin 1 3 190305701-190322475 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB002602, HPA048319 Enhanced Endometrial cancer:2.00e-4 (unfavourable), Pancreatic cancer:5.23e-4 (unfavourable) Expressed in all Tissue enhanced skin: 306.2;smooth muscle: 186.0 liver: 158.4 Cell line enhanced EFO-21: 613.4;HaCaT: 206.6;hTCEpi: 206.7;RPTEC TERT1: 310.7;RT4: 210.1 +PYGO2 ENSG00000163348 Pygopus family PHD finger 2 1 154957026-154963853 Predicted intracellular proteins Evidence at protein level HPA023689 Supported Approved Nucleoplasm Liver cancer:3.88e-6 (unfavourable), Urothelial cancer:1.76e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 51.7 Expressed in all +HIPK1 KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2 ENSG00000163349 Homeodomain interacting protein kinase 1 1 113929192-113977869 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA016664 Approved Approved Nucleoplasm
Centrosome
Cytosol Expressed in all Expressed in all bone marrow: 89.7 Expressed in all +LENEP LEP503 ENSG00000163352 Lens epithelial protein 1 154993586-154994315 Predicted intracellular proteins Evidence at transcript level Not detected Not detected thyroid gland: 0.2 Not detected +DCST2 FLJ32934 ENSG00000163354 DC-STAMP domain containing 2 1 155018520-155033781 Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced skin: 5.0;testis: 4.2 duodenum,fallopian tube: 1.3 Cell line enhanced U-266/70: 1.1 +DCST1 FLJ32785 ENSG00000163357 DC-STAMP domain containing 1 1 155033824-155050930 Predicted membrane proteins Evidence at protein level HPA060314 Uncertain Not detected Group enriched 5 skin: 3.7;testis: 6.1 small intestine: 0.9 Cell line enhanced HaCaT: 1.8;RPMI-8226: 1.7 +COL6A3 ENSG00000163359 Collagen type VI alpha 3 chain 2 237324003-237414375 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA010080 Supported Renal cancer:5.57e-11 (unfavourable) Expressed in all Tissue enhanced smooth muscle: 557.1 gallbladder: 375.3 Cell line enhanced ASC diff: 2271.2;ASC TERT1: 2960.3;BJ hTERT+: 1039.3;HSkMC: 1966.4 +C1orf106 FLJ10901 ENSG00000163362 Chromosome 1 open reading frame 106 1 200891048-200915735 Predicted intracellular proteins Evidence at transcript level HPA027499, HPA027511 Uncertain Endometrial cancer:1.78e-5 (unfavourable) Expressed in all Tissue enhanced small intestine: 69.7 duodenum: 54.3 Cell line enhanced BEWO: 60.4;HaCaT: 66.8 +YY1AP1 HCCA2, YAP, YY1AP ENSG00000163374 YY1 associated protein 1 1 155659443-155689000 Predicted intracellular proteins Evidence at protein level HPA006986, HPA064249 Uncertain Approved Nucleoli fibrillar center Renal cancer:2.01e-6 (unfavourable) Expressed in all Expressed in all testis: 130.2 Expressed in all +KBTBD8 KIAA1842, TA-KRP ENSG00000163376 Kelch repeat and BTB domain containing 8 3 66998307-67011210 Predicted intracellular proteins Evidence at protein level HPA041285, HPA069190 Approved Mixed Tissue enhanced lymph node: 24.3;tonsil: 18.9 testis: 14.5 Cell line enhanced Daudi: 44.8;U-698: 29.8 +FAM19A4 TAFA-4 ENSG00000163377 Family with sequence similarity 19 member A4, C-C motif chemokine like 3 68731766-68953297 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enriched 10 adrenal gland: 18.5 gallbladder: 1.9 Cell line enhanced HAP1: 1.8;NTERA-2: 8.8;SCLC-21H: 1.1 +EOGT AER61, C3orf64, FLJ33770 ENSG00000163378 EGF domain specific O-linked N-acetylglucosamine transferase 3 68975214-69013961 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA019460 Approved Approved Nucleoplasm
Nuclear membrane
Cytosol Renal cancer:8.97e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 50.3 Mixed +LMOD3 ENSG00000163380 Leiomodin 3 3 69106872-69123032 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036034 Uncertain Tissue enriched Group enriched 17 heart muscle: 73.7;skeletal muscle: 162.2 esophagus: 6.9 Cell line enhanced HSkMC: 2.1 +NAXE AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1 ENSG00000163382 NAD(P)HX epimerase 1 156591762-156594299 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA043766, HPA048164 Enhanced Enhanced Nucleoplasm
Cytosol Endometrial cancer:4.94e-4 (unfavourable) Expressed in all Expressed in all epididymis: 112.2 Expressed in all +POGLUT1 9630046K23Rik, C3orf9, hCLP46, KDELCL1, KTELC1, MDS010, MDSRP, MGC32995, Rumi ENSG00000163389 Protein O-glucosyltransferase 1 3 119468938-119494708 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037855, HPA037856 Approved Renal cancer:7.02e-7 (unfavourable), Urothelial cancer:2.23e-4 (favourable) Expressed in all Mixed seminal vesicle: 16.5 Expressed in all +SLC22A15 FLIPT1 ENSG00000163393 Solute carrier family 22 member 15 1 115976498-116070054 Predicted membrane proteins, Transporters Evidence at protein level HPA019785 Approved Expressed in all Tissue enhanced bone marrow: 20.5 skin: 11.1 Cell line enhanced hTCEpi: 26.0;hTERT-HME1: 36.4 +CCKAR ENSG00000163394 Cholecystokinin A receptor 4 26481400-26490462 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Group enriched 10 gallbladder: 47.2;stomach: 15.2 tonsil: 3.1 Not detected +IGFN1 DKFZp434B1231, EEF1A2BP1 ENSG00000163395 Immunoglobulin-like and fibronectin type III domain containing 1 1 201190825-201228952 Predicted intracellular proteins Evidence at protein level HPA050415 Enhanced Approved Midbody ring Renal cancer:1.27e-8 (unfavourable) Group enriched Group enriched 6 endometrium: 17.1;epididymis: 18.4;skeletal muscle: 60.1 cerebral cortex: 5.6 Cell line enriched 6 HeLa: 41.8 +ATP1A1 ENSG00000163399 ATPase Na+/K+ transporting subunit alpha 1 1 116372668-116410261 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB018702, CAB069993 Enhanced Renal cancer:8.98e-8 (favourable), Liver cancer:1.42e-4 (unfavourable), Urothelial cancer:4.01e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 2487.1 Expressed in all +SLC15A2 PEPT2 ENSG00000163406 Solute carrier family 15 member 2 3 121894089-121944102 Predicted membrane proteins, Transporters Evidence at protein level Cervical cancer:2.37e-4 (favourable), Lung cancer:6.74e-4 (favourable), Endometrial cancer:6.96e-4 (favourable) Mixed Tissue enhanced cervix, uterine: 78.5;prostate: 64.9 epididymis: 47.8 Mixed +EIF4E3 MGC39820 ENSG00000163412 Eukaryotic translation initiation factor 4E family member 3 3 71675416-71754773 Predicted intracellular proteins Evidence at protein level HPA058649 Approved Nucleoli fibrillar center Ovarian cancer:4.64e-5 (favourable), Renal cancer:6.99e-5 (favourable), Lung cancer:6.63e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 54.7 Cell line enhanced U-937: 39.6 +PROK2 BV8, KAL4, MIT1, PK2 ENSG00000163421 Prokineticin 2 3 71771656-71785206 Disease related genes, Predicted secreted proteins Evidence at protein level HPA041408 Uncertain Tissue enhanced Tissue enhanced appendix: 30.3;bone marrow: 52.7;testis: 24.1 adipose tissue: 11.2 Group enriched 5 HL-60: 8.9;NB-4: 6.1;NTERA-2: 6.5;U-266/70: 11.1;U-266/84: 17.7;U-937: 7.9 +C3orf30 FLJ32859, TSCPA ENSG00000163424 Chromosome 3 open reading frame 30 3 119146150-119160042 Predicted intracellular proteins Evidence at protein level HPA062468 Enhanced Not detected Tissue enriched 438 testis: 94.4 kidney: 0.2 Not detected +LRRC58 ENSG00000163428 Leucine rich repeat containing 58 3 120324509-120349339 Predicted intracellular proteins Evidence at protein level HPA057574 Uncertain Approved Nucleus
Cytosol Liver cancer:4.98e-4 (unfavourable), Thyroid cancer:6.18e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 30.1 Expressed in all +FSTL1 FRP, FSL1, OCC-1, OCC1, tsc36 ENSG00000163430 Follistatin like 1 3 120392293-120451253 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035251, HPA040815 Uncertain Approved Vesicles
Cytosol Renal cancer:1.33e-4 (unfavourable) Expressed in all Expressed in all placenta: 656.3 Cell line enhanced BJ: 1888.8;fHDF/TERT166: 2153.3;HBF TERT88: 1729.6 +LMOD1 1D, 64kD, D1 ENSG00000163431 Leiomodin 1 1 201896452-201946588 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028325, HPA028435, HPA030097 Enhanced Approved Cytosol Liver cancer:2.52e-5 (favourable), Renal cancer:1.05e-4 (unfavourable) Expressed in all Mixed seminal vesicle: 331.2 Group enriched 10 ASC diff: 10.7;BJ: 17.8;BJ hTERT+: 27.6;fHDF/TERT166: 13.3;HSkMC: 10.4 +ELF3 EPR-1, ERT, ESE-1, ESX ENSG00000163435 E74 like ETS transcription factor 3 1 202007945-202017188 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003316, HPA003479 Enhanced Enhanced Nucleoplasm Mixed Mixed small intestine: 161.7 Cell line enhanced A549: 188.9;CAPAN-2: 259.7;RT4: 171.2;SK-BR-3: 304.2 +PDCL2 GCPHLP ENSG00000163440 Phosducin like 2 4 55556525-55592212 Predicted intracellular proteins Evidence at protein level HPA048260 Enhanced Group enriched Tissue enriched 306 testis: 110.4 skin: 0.3 Cell line enhanced HaCaT: 1.7 +TMEM183A C1orf37 ENSG00000163444 Transmembrane protein 183A 1 203007386-203024848 Predicted membrane proteins Evidence at protein level HPA072607 Approved Nucleus
Plasma membrane
Cell Junctions Liver cancer:2.62e-4 (unfavourable) Expressed in all Expressed in all testis: 59.1 Expressed in all +TMEM169 FLJ34263 ENSG00000163449 Transmembrane protein 169 2 216081866-216102783 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA062462, HPA062797, HPA070657 Uncertain Approved Nucleoplasm
Centrosome
Cytosol Mixed Tissue enhanced cerebral cortex: 12.0 thyroid gland: 4.8 Cell line enhanced AF22: 8.9;RPTEC TERT1: 10.0;SCLC-21H: 13.4;SH-SY5Y: 17.3 +IGFBP7 FSTL2, IGFBP-7, MAC25, PSF ENSG00000163453 Insulin like growth factor binding protein 7 4 57030773-57110385 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002196, CAB020668 Approved Uncertain Golgi apparatus Expressed in all Expressed in all seminal vesicle: 916.3 Cell line enhanced BJ: 585.7;BJ hTERT+: 522.8;EFO-21: 407.8;RPTEC TERT1: 516.3;TIME: 821.5 +TRIM46 FLJ23229, TRIFIC ENSG00000163462 Tripartite motif containing 46 1 155173787-155184971 Predicted intracellular proteins Evidence at protein level HPA030389, HPA055583 Enhanced Approved Intermediate filaments
Cytosol Endometrial cancer:2.61e-7 (unfavourable) Mixed Tissue enhanced cerebral cortex: 7.9;epididymis: 4.0 smooth muscle: 1.5 Cell line enhanced SH-SY5Y: 11.1 +KRTCAP2 KCP2 ENSG00000163463 Keratinocyte associated protein 2 1 155169408-155173475 Predicted membrane proteins Evidence at protein level Renal cancer:9.70e-11 (unfavourable) Expressed in all Expressed in all epididymis: 241.8 Expressed in all +CXCR1 CD181, CDw128a, CKR-1, CMKAR1, IL8RA ENSG00000163464 C-X-C motif chemokine receptor 1 2 218162845-218166995 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA031991 Uncertain Mixed Tissue enhanced appendix: 35.1;spleen: 25.0 adipose tissue: 15.7 Cell line enriched 32 HMC-1: 5.0 +ARPC2 ARC34, p34-Arc ENSG00000163466 Actin related protein 2/3 complex subunit 2 2 218217094-218254356 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001994, HPA008352 Approved Supported Golgi apparatus
Cytosol Renal cancer:1.07e-7 (unfavourable), Liver cancer:3.63e-5 (unfavourable) Expressed in all Expressed in all lymph node: 537.0 Expressed in all +TSACC C1orf182, SIP, SSTK-IP ENSG00000163467 TSSK6 activating cochaperone 1 156337314-156346995 Predicted intracellular proteins Evidence at protein level HPA029897 Approved Nucleus
Nuclear bodies Tissue enhanced Tissue enriched 506 testis: 1514.6 epididymis: 2.9 Mixed +CCT3 Cctg, TRIC5 ENSG00000163468 Chaperonin containing TCP1 subunit 3 1 156308968-156367873 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006543 Approved Supported Plasma membrane
Cytosol Liver cancer:3.87e-7 (unfavourable), Renal cancer:6.34e-4 (unfavourable) Expressed in all Expressed in all testis: 206.2 Expressed in all +TMEM79 FLJ16057, FLJ32254, MATT, MGC13102 ENSG00000163472 Transmembrane protein 79 1 156282935-156293185 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055214 Enhanced Approved Nucleoli fibrillar center Renal cancer:4.31e-7 (unfavourable), Liver cancer:2.61e-5 (unfavourable) Expressed in all Group enriched 6 esophagus: 61.6;prostate: 45.5;skin: 66.8 tonsil: 10.3 Mixed +SSR2 TLAP, TRAPB ENSG00000163479 Signal sequence receptor subunit 2 1 156009048-156020959 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.00e-7 (unfavourable), Liver cancer:2.86e-4 (unfavourable) Expressed in all Expressed in all epididymis: 551.1 Expressed in all +RNF25 AO7, FLJ13906 ENSG00000163481 Ring finger protein 25 2 218663864-218672411 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036420, HPA036421 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:6.58e-4 (unfavourable) Expressed in all Expressed in all testis: 14.6 Expressed in all +STK36 FU, KIAA1278 ENSG00000163482 Serine/threonine kinase 36 2 218672026-218702716 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027409, HPA027453, HPA030058 Approved Supported Cytosol Liver cancer:5.20e-4 (unfavourable) Expressed in all Expressed in all testis: 59.0 Expressed in all +ADORA1 RDC7 ENSG00000163485 Adenosine A1 receptor 1 203090654-203167405 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA044383 Supported Plasma membrane Tissue enhanced Tissue enhanced cerebral cortex: 50.2;testis: 25.4 parathyroid gland: 18.9 Cell line enhanced CACO-2: 33.2;RH-30: 62.4;RPTEC TERT1: 23.7;SK-BR-3: 26.3 +NEK10 FLJ32685 ENSG00000163491 NIMA related kinase 10 3 27110085-27369460 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038941 Uncertain Approved Nucleoplasm
Vesicles Breast cancer:4.20e-4 (favourable) Tissue enriched Tissue enhanced testis: 65.9 breast: 18.6 Cell line enhanced LHCN-M2: 6.8;U-2 OS: 7.1 +CCDC141 CAMDI, FLJ39502 ENSG00000163492 Coiled-coil domain containing 141 2 178830269-179050086 Predicted intracellular proteins Evidence at protein level HPA012718 Approved Nucleoplasm Not detected Tissue enriched 13 heart muscle: 50.2 lung: 3.9 Cell line enhanced CACO-2: 4.0;HEL: 6.8;RH-30: 3.7;U-266/70: 3.7;U-698: 4.4 +FEV Pet-1 ENSG00000163497 FEV, ETS transcription factor 2 218981087-218985657 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067679 Supported Supported Nuclear speckles Pancreatic cancer:4.85e-4 (favourable) Group enriched Tissue enhanced adrenal gland: 2.1;duodenum: 2.9;prostate: 1.9;stomach: 2.4 small intestine: 1.6 Group enriched 6 HMC-1: 22.4;SH-SY5Y: 34.6 +CRYBA2 ENSG00000163499 Crystallin beta A2 2 218990189-218993421 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA062293 Supported Pancreatic cancer:7.62e-4 (favourable) Tissue enriched Tissue enhanced adrenal gland: 4.6;stomach: 4.6 small intestine: 3.0 Cell line enriched 6 BEWO: 69.8 +IHH BDA1, HHG2 ENSG00000163501 Indian hedgehog 2 219054420-219060467 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Endometrial cancer:3.67e-6 (favourable) Tissue enhanced Group enriched 6 cervix, uterine: 8.9;colon: 21.0;duodenum: 14.9;endometrium: 31.4;rectum: 16.7;small intestine: 16.5;stomach: 15.3 prostate: 3.2 Cell line enriched 11 CACO-2: 16.8 +KIAA1524 CIP2A ENSG00000163507 KIAA1524 3 108549869-108589644 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039570 Approved Supported Plasma membrane
Cytosol Endometrial cancer:6.24e-5 (unfavourable), Renal cancer:1.42e-4 (unfavourable), Pancreatic cancer:9.18e-4 (unfavourable) Expressed in all Mixed testis: 10.3 Mixed +EOMES TBR2 ENSG00000163508 Eomesodermin 3 27715949-27722711 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028896 Uncertain Renal cancer:9.45e-6 (unfavourable) Tissue enhanced Tissue enhanced lymph node: 18.2;spleen: 19.4 tonsil: 5.3 Cell line enhanced HDLM-2: 7.3;SCLC-21H: 4.9 +CWC22 EIF4GL, fSAPb, KIAA1604, NCM ENSG00000163510 CWC22 spliceosome associated protein homolog 2 179944876-180007113 Predicted intracellular proteins Evidence at protein level HPA036748 Approved Supported Nuclear speckles
Cytosol Renal cancer:7.76e-5 (unfavourable), Liver cancer:7.42e-4 (unfavourable) Expressed in all Expressed in all endometrium: 28.9 Expressed in all +AZI2 AZ2, FLJ21939, NAP1 ENSG00000163512 5-azacytidine induced 2 3 28315003-28349127 Predicted intracellular proteins Evidence at protein level HPA035258 Approved Liver cancer:1.95e-4 (unfavourable), Urothelial cancer:2.77e-4 (unfavourable) Expressed in all Expressed in all testis: 30.7 Expressed in all +TGFBR2 MFS2 ENSG00000163513 Transforming growth factor beta receptor 2 3 30606502-30694142 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB073537 Supported Plasma membrane Expressed in all Expressed in all adipose tissue: 292.3 Cell line enhanced ASC TERT1: 366.2;LHCN-M2: 371.8;TIME: 336.9 +RETNLB FIZZ2, HXCP2, RELMb ENSG00000163515 Resistin like beta 3 108743424-108757384 Predicted secreted proteins Evidence at transcript level HPA049152 Approved Colorectal cancer:6.86e-5 (favourable) Tissue enriched Tissue enhanced colon: 73.5;rectum: 270.7 small intestine: 36.9 Not detected +ANKZF1 FLJ10415, ZNF744 ENSG00000163516 Ankyrin repeat and zinc finger domain containing 1 2 219229757-219236669 Predicted intracellular proteins Evidence at protein level HPA035208 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:2.01e-6 (unfavourable), Liver cancer:3.09e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 16.8 Expressed in all +HDAC11 ENSG00000163517 Histone deacetylase 11 3 13479724-13506424 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Renal cancer:7.88e-10 (favourable), Liver cancer:1.20e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 66.7 Cell line enhanced T-47d: 39.9 +FCRL4 CD307d, FCRH4, IGFP2, IRTA1 ENSG00000163518 Fc receptor like 4 1 157573749-157598080 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level HPA054030 Approved Not detected Tissue enhanced appendix: 3.6;lymph node: 4.4;tonsil: 9.6 spleen: 1.1 Cell line enriched 36 U-266/70: 3.5 +TRAT1 HSPC062, TCRIM, TRIM ENSG00000163519 T-cell receptor associated transmembrane adaptor 1 3 108822698-108855005 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002356, CAB026130 Enhanced Mixed Tissue enhanced appendix: 14.0;lymph node: 26.4 spleen: 11.5 Cell line enriched 39 MOLT-4: 58.7 +FBLN2 ENSG00000163520 Fibulin 2 3 13549131-13638422 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001934, CAB018622 Enhanced Supported Plasma membrane Liver cancer:3.17e-4 (favourable), Endometrial cancer:9.48e-4 (unfavourable) Expressed in all Mixed adipose tissue: 142.2 Cell line enhanced ASC diff: 262.8;fHDF/TERT166: 204.8;HMC-1: 273.5;HSkMC: 161.5 +GLB1L MGC10771 ENSG00000163521 Galactosidase beta 1 like 2 219236606-219245478 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043058 Enhanced Expressed in all Tissue enhanced testis: 95.4 fallopian tube: 37.3 Mixed +STT3B FLJ90106, SIMP, STT3-B ENSG00000163527 STT3B, catalytic subunit of the oligosaccharyltransferase complex 3 31532638-31637622 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA036448, HPA036646 Approved Supported Endoplasmic reticulum Colorectal cancer:7.91e-5 (favourable) Expressed in all Expressed in all testis: 165.5 Expressed in all +CHCHD4 FLJ31709, MIA40, TIMM40 ENSG00000163528 Coiled-coil-helix-coiled-coil-helix domain containing 4 3 14112077-14124870 Predicted intracellular proteins Evidence at protein level HPA034688, HPA063727 Uncertain Supported Mitochondria Renal cancer:8.63e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 31.2 Expressed in all +DPPA2 CT100, PESCRG1 ENSG00000163530 Developmental pluripotency associated 2 3 109293788-109316517 Predicted intracellular proteins Evidence at protein level HPA036134 Uncertain Approved Nucleus Tissue enriched Tissue enriched 11 testis: 6.5 placenta: 0.5 Cell line enhanced BEWO: 5.8;EFO-21: 10.7 +NFASC FLJ46866, KIAA0756, NF, NRCAML ENSG00000163531 Neurofascin 1 204828651-205022822 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008832 Enhanced Renal cancer:2.93e-5 (unfavourable), Pancreatic cancer:3.21e-5 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 55.7 seminal vesicle: 22.4 Cell line enhanced BJ: 23.3;fHDF/TERT166: 39.1;SCLC-21H: 26.9;U-138 MG: 62.0;U-87 MG: 30.5 +FCRL1 CD307a, FCRH1, IFGP1, IRTA5 ENSG00000163534 Fc receptor like 1 1 157794403-157820105 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013323 Enhanced Mixed Tissue enhanced lymph node: 30.3;spleen: 23.5;tonsil: 20.0 appendix: 12.5 Group enriched 31 Daudi: 3.7;U-698: 11.9 +SGO2 FLJ25211, SGOL2, TRIPIN ENSG00000163535 Shugoshin 2 2 200510008-200583782 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035163, HPA040817 Enhanced Enhanced Nucleoplasm
Nuclear bodies Mixed Tissue enriched 6 testis: 59.6 lymph node: 9.2 Expressed in all +SERPINI1 neuroserpin, PI12 ENSG00000163536 Serpin family I member 1 3 167735243-167825568 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001565, CAB026059, HPA056092 Enhanced Approved Cytosol Liver cancer:4.25e-4 (unfavourable) Expressed in all Tissue enriched 10 cerebral cortex: 322.1 kidney: 31.3 Mixed +CLASP2 KIAA0627 ENSG00000163539 Cytoplasmic linker associated protein 2 3 33496245-33718356 Predicted intracellular proteins Evidence at protein level HPA067071 Supported Golgi apparatus
Cytosol Renal cancer:1.48e-6 (favourable) Expressed in all Tissue enriched 6 cerebral cortex: 193.2 endometrium: 34.2 Expressed in all +SUCLG1 ENSG00000163541 Succinate-CoA ligase alpha subunit 2 84423523-84460045 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA036683, HPA036684 Enhanced Supported Plasma membrane
Mitochondria Renal cancer:2.21e-8 (favourable), Endometrial cancer:5.23e-4 (unfavourable) Expressed in all Expressed in all kidney: 471.2 Expressed in all +NUAK2 FLJ90349, SNARK ENSG00000163545 NUAK family kinase 2 1 205302059-205321791 Enzymes, Predicted membrane proteins Evidence at protein level HPA008958 Uncertain Approved Nucleus
Nucleoli fibrillar center
Cytosol Endometrial cancer:3.01e-7 (unfavourable), Pancreatic cancer:7.94e-6 (favourable) Expressed in all Mixed esophagus: 22.0 Cell line enhanced BEWO: 42.0;RPTEC TERT1: 30.2 +SPTA1 EL2 ENSG00000163554 Spectrin alpha, erythrocytic 1 1 158610706-158686698 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016193, HPA028048, HPA028253, CAB037246 Supported Not detected Tissue enriched 19 bone marrow: 47.1 placenta: 2.5 Group enriched 7 HEL: 7.6;K-562: 34.1 +PRKCI DXS1179E, PKCI ENSG00000163558 Protein kinase C iota 3 170222365-170305981 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA026574, HPA038635 Approved Enhanced Microtubules
Cytokinetic bridge
Cytosol Endometrial cancer:3.93e-6 (unfavourable), Pancreatic cancer:1.22e-4 (unfavourable), Liver cancer:3.02e-4 (unfavourable), Renal cancer:3.10e-4 (favourable) Expressed in all Expressed in all thyroid gland: 39.9 Expressed in all +MNDA PYHIN3 ENSG00000163563 Myeloid cell nuclear differentiation antigen 1 158831317-158849506 Predicted intracellular proteins Evidence at protein level HPA034532, HPA073215 Enhanced Supported Nucleoplasm
Nucleoli Expressed in all Tissue enhanced bone marrow: 194.8;spleen: 144.9 appendix: 111.3 Group enriched 13 NB-4: 93.3;THP-1: 185.6;U-937: 141.2 +PYHIN1 IFIX, MGC23885 ENSG00000163564 Pyrin and HIN domain family member 1 1 158930796-158977054 Predicted intracellular proteins Evidence at protein level HPA051224 Enhanced Mixed Tissue enhanced lymph node: 26.3;spleen: 19.2 tonsil: 11.3 Cell line enriched 6 U-698: 33.8 +IFI16 IFNGIP1, PYHIN2 ENSG00000163565 Interferon gamma inducible protein 16 1 158999968-159055155 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002134, CAB016293 Enhanced Supported Nucleus
Nucleoli
Cytosol Renal cancer:1.11e-16 (unfavourable) Expressed in all Expressed in all lymph node: 163.5 Mixed +AIM2 PYHIN4 ENSG00000163568 Absent in melanoma 2 1 159062484-159147096 Predicted intracellular proteins Evidence at protein level HPA031365, HPA040309 Uncertain Supported Nucleoplasm
Mitochondria
Cytosol Mixed Tissue enhanced lymph node: 52.5;spleen: 30.9;tonsil: 40.1 appendix: 26.0 Cell line enhanced Daudi: 60.6;HDLM-2: 110.5;Karpas-707: 32.8;U-266/70: 28.9;U-87 MG: 34.1 +EFHB CFAP21, FLJ25200 ENSG00000163576 EF-hand domain family member B 3 19879472-19947025 Predicted intracellular proteins Evidence at protein level HPA078067 Approved Nucleoli Mixed Group enriched 6 fallopian tube: 25.5;testis: 25.8 cerebral cortex: 4.3 Cell line enriched 30 RPTEC TERT1: 14.9 +EIF5A2 ENSG00000163577 Eukaryotic translation initiation factor 5A2 3 170888415-170908693 Predicted intracellular proteins, Transporters Evidence at protein level HPA029090 Approved Supported Vesicles Head and neck cancer:7.42e-4 (unfavourable) Expressed in all Tissue enhanced testis: 36.7 smooth muscle: 10.4 Mixed +SLC2A2 GLUT2 ENSG00000163581 Solute carrier family 2 member 2 3 170996348-171026750 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB010444, HPA028997, HPA028998 Enhanced Approved Nucleoplasm Liver cancer:2.63e-5 (favourable) Tissue enriched Tissue enriched 7 liver: 433.0 duodenum: 65.7 Group enriched 61 CACO-2: 6.7;Hep G2: 18.6 +RPL22L1 ENSG00000163584 Ribosomal protein L22 like 1 3 170864875-170870483 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA048060, HPA056207, HPA068294 Uncertain Approved Nucleus
Nucleoli Renal cancer:5.13e-12 (unfavourable), Ovarian cancer:8.60e-5 (favourable) Expressed in all Expressed in all appendix: 87.1 Expressed in all +FABP1 L-FABP ENSG00000163586 Fatty acid binding protein 1 2 88122982-88128116 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002305, HPA028275 Enhanced Approved Nucleoplasm
Cytosol Group enriched Group enriched 7 colon: 4552.0;duodenum: 4123.5;liver: 5672.8;rectum: 3081.5;small intestine: 4506.9 kidney: 602.3 Group enriched 6 CACO-2: 84.1;Hep G2: 221.3 +PPM1L PP2CE ENSG00000163590 Protein phosphatase, Mg2+/Mn2+ dependent 1L 3 160755602-161078907 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019891, HPA019953 Approved Approved Nucleoplasm
Cytosol Breast cancer:4.90e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 39.6 cerebral cortex: 27.9 Group enriched 5 HDLM-2: 73.7;U-266/70: 57.7 +ICA1L ALS2CR14, ALS2CR15 ENSG00000163596 Islet cell autoantigen 1 like 2 202773150-202871985 Predicted intracellular proteins Evidence at protein level HPA042507 Approved Supported Mitochondria Mixed Mixed cerebral cortex: 22.4 Cell line enhanced BEWO: 21.1 +CTLA4 CD, CD152, CELIAC3, GSE, IDDM12 ENSG00000163599 Cytotoxic T-lymphocyte associated protein 4 2 203867786-203873960 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Head and neck cancer:4.48e-5 (favourable) Mixed Tissue enhanced appendix: 23.5;lymph node: 31.9 tonsil: 15.3 Group enriched 5 SK-MEL-30: 2.4;U-266/70: 3.5;U-266/84: 9.7 +ICOS AILIM, CD278 ENSG00000163600 Inducible T-cell costimulator 2 203936748-203961577 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level CAB032575 Approved Head and neck cancer:1.80e-4 (favourable) Mixed Tissue enhanced bone marrow: 10.9;lymph node: 16.9;tonsil: 14.8 appendix: 10.2 Group enriched 69 HEL: 4.0;MOLT-4: 9.6 +RYBP AAP1, DEDAF, YEAF1 ENSG00000163602 RING1 and YY1 binding protein 3 72371825-72446621 Predicted intracellular proteins Evidence at protein level HPA053357 Approved Supported Nucleoplasm Renal cancer:2.50e-5 (favourable) Expressed in all Mixed endometrium: 30.7 Expressed in all +PPP4R2 ENSG00000163605 Protein phosphatase 4 regulatory subunit 2 3 72996785-73069199 Predicted intracellular proteins Evidence at protein level HPA034695, HPA039837, HPA073758 Approved Enhanced Nucleoplasm Expressed in all Expressed in all bone marrow: 66.7 Expressed in all +CD200R1 CD200R, HCRTR2, MOX2R, OX2R ENSG00000163606 CD200 receptor 1 3 112921209-112975122 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA068512 Supported Plasma membrane Mixed Tissue enhanced spleen: 14.5 placenta: 10.2 Cell line enriched 8 HEL: 26.4 +GTPBP8 HSPC135 ENSG00000163607 GTP binding protein 8 (putative) 3 112990918-113015060 Predicted intracellular proteins Evidence at protein level HPA034831, HPA058631 Approved Enhanced Mitochondria Renal cancer:3.07e-5 (favourable) Expressed in all Expressed in all testis: 33.0 Expressed in all +NEPRO C3orf17, DKFZP434F2021, NET17 ENSG00000163608 Nucleolus and neural progenitor protein 3 113002440-113019861 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA069654 Supported Nucleus
Nucleoli Endometrial cancer:1.13e-4 (unfavourable), Liver cancer:4.25e-4 (unfavourable) Expressed in all Expressed in all testis: 20.8 Expressed in all +SPICE1 CCDC52, SPICE ENSG00000163611 Spindle and centriole associated protein 1 3 113442718-113515187 Predicted intracellular proteins Evidence at protein level HPA064843 Approved Supported Centrosome Expressed in all Mixed endometrium: 17.7 Expressed in all +CCDC191 KIAA1407 ENSG00000163617 Coiled-coil domain containing 191 3 113964137-114056613 Predicted intracellular proteins Evidence at protein level HPA047833 Approved Approved Mitochondria Urothelial cancer:3.45e-4 (favourable) Expressed in all Mixed fallopian tube: 18.8 Mixed +CADPS CAPS, CAPS1, KIAA1121, UNC-31 ENSG00000163618 Calcium dependent secretion activator 3 62398346-62875389 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059328 Enhanced Approved Vesicles Mixed Group enriched 8 adrenal gland: 21.6;cerebral cortex: 94.1 heart muscle: 7.5 Cell line enhanced SCLC-21H: 23.2;SK-MEL-30: 7.0;U-698: 8.9;U-87 MG: 20.1 +NKX6-1 Nkx6.1, NKX6A ENSG00000163623 NK6 homeobox 1 4 84491987-84498450 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036774, CAB070169 Supported Supported Nucleoplasm Mixed Tissue enhanced esophagus: 6.9;thyroid gland: 2.9 testis: 1.4 Cell line enhanced AF22: 4.0;HAP1: 6.0;HEK 293: 4.7;HMC-1: 3.4;U-2197: 5.9 +CDS1 ENSG00000163624 CDP-diacylglycerol synthase 1 4 84582979-84651338 Enzymes, Predicted membrane proteins Evidence at protein level HPA036187, HPA064546 Enhanced Approved Nucleus
Nuclear membrane Renal cancer:0.00e+0 (favourable), Colorectal cancer:5.22e-4 (favourable) Expressed in all Mixed fallopian tube: 49.6 Cell line enhanced CAPAN-2: 39.2;hTCEpi: 39.6;SK-BR-3: 44.9 +WDFY3 ALFY, KIAA0993, ZFYVE25 ENSG00000163625 WD repeat and FYVE domain containing 3 4 84669610-84966391 Predicted intracellular proteins Evidence at protein level HPA042734, HPA048572 Approved Approved Nucleoli
Plasma membrane
Cytosol Renal cancer:3.64e-5 (favourable), Stomach cancer:9.35e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.2 Mixed +COX18 FLJ38991 ENSG00000163626 COX18, cytochrome c oxidase assembly factor 4 73052362-73069755 Predicted membrane proteins Evidence at protein level HPA046772, HPA049489 Enhanced Renal cancer:8.22e-7 (favourable), Colorectal cancer:6.31e-4 (favourable) Expressed in all Mixed thyroid gland: 5.4 Expressed in all +PTPN13 PTP-BAS, PTP-BL, PTP1E, PTPL1 ENSG00000163629 Protein tyrosine phosphatase, non-receptor type 13 4 86594315-86815171 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB002213, HPA048888, HPA065290 Approved Approved Plasma membrane
Cytosol Mixed Mixed skin: 65.9 Cell line enhanced AF22: 114.7 +SYNPR MGC26651, SPO ENSG00000163630 Synaptoporin 3 63228315-63616921 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051368, HPA061671 Enhanced Tissue enhanced Tissue enriched 27 cerebral cortex: 78.2 heart muscle: 2.9 Cell line enhanced SCLC-21H: 1.2 +ALB ENSG00000163631 Albumin 4 73397114-73421412 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB006262, HPA031024, HPA031025 Supported Enhanced Endoplasmic reticulum
Golgi apparatus Stomach cancer:7.87e-4 (unfavourable) Tissue enriched Tissue enriched 220 liver: 105947.0 kidney: 482.5 Cell line enriched 33 Hep G2: 3030.6 +C3orf49 ENSG00000163632 Chromosome 3 open reading frame 49 3 63819362-63848636 Predicted intracellular proteins Evidence at transcript level HPA053582 Uncertain Not detected Tissue enhanced cerebral cortex: 1.2;testis: 2.1 skin: 0.5 Not detected +C4orf36 MGC26744 ENSG00000163633 Chromosome 4 open reading frame 36 4 86876205-86936202 Predicted intracellular proteins Evidence at protein level HPA057434 Uncertain Approved Focal adhesion sites
Cytosol Renal cancer:7.69e-5 (favourable) Mixed Tissue enhanced testis: 10.6 skin: 5.7 Mixed +THOC7 FLJ23445, fSAP24, NIF3L1BP1 ENSG00000163634 THO complex 7 3 63833870-63863903 Predicted intracellular proteins Evidence at protein level HPA044143 Approved Supported Nuclear speckles
Cytosol Expressed in all Expressed in all breast: 84.4 Expressed in all +ATXN7 ADCAII, OPCA3, SCA7 ENSG00000163635 Ataxin 7 3 63864557-64003462 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034989 Supported Nucleoplasm
Cytosol Head and neck cancer:1.22e-4 (favourable) Expressed in all Expressed in all testis: 33.7 Expressed in all +PSMD6 KIAA0107, p44S10, Rpn7, S10 ENSG00000163636 Proteasome 26S subunit, non-ATPase 6 3 64010549-64024010 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036921, HPA036922 Uncertain Supported Golgi apparatus
Vesicles Liver cancer:1.68e-4 (unfavourable) Expressed in all Expressed in all testis: 216.4 Cell line enriched 5 MCF7: 1051.2 +PRICKLE2 DKFZp686D143 ENSG00000163637 Prickle planar cell polarity protein 2 3 64092242-64445476 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035493 Approved Golgi apparatus
Vesicles Mixed Mixed endometrium: 29.7 Cell line enhanced ASC diff: 16.5;HSkMC: 16.1;U-87 MG: 15.2 +ADAMTS9 KIAA1312 ENSG00000163638 ADAM metallopeptidase with thrombospondin type 1 motif 9 3 64515654-64688000 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028567, HPA028577, HPA028601 Approved Approved Endoplasmic reticulum
Vesicles Expressed in all Tissue enhanced placenta: 45.1 adipose tissue: 32.1 Cell line enhanced RPTEC TERT1: 20.9;SH-SY5Y: 136.2;WM-115: 27.9 +PPM1K BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm ENSG00000163644 Protein phosphatase, Mg2+/Mn2+ dependent 1K 4 88257620-88284769 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020066, HPA020862, HPA023891 Approved Supported Mitochondria Expressed in all Expressed in all heart muscle: 61.4 Mixed +ERICH6 C3orf44, ERICH6A, FAM194A, MGC39662 ENSG00000163645 Glutamate rich 6 3 150659885-150703971 Predicted intracellular proteins Evidence at protein level HPA048373 Enhanced Not detected Tissue enriched 24 testis: 51.6 epididymis: 2.1 Cell line enhanced SH-SY5Y: 1.7;U-266/84: 1.9 +CLRN1 RP61, USH3, USH3A ENSG00000163646 Clarin 1 3 150926163-150972999 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA054636 Uncertain Not detected Group enriched 5 adrenal gland: 6.7;duodenum: 1.5 testis: 0.7 Cell line enriched 31 NTERA-2: 3.5 +GMPS ENSG00000163655 Guanine monophosphate synthase 3 155870536-155944026 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046630 Approved Cytosol Liver cancer:8.73e-7 (unfavourable), Endometrial cancer:5.54e-5 (unfavourable), Pancreatic cancer:1.04e-4 (unfavourable) Expressed in all Expressed in all testis: 181.7 Expressed in all +TIPARP DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1 ENSG00000163659 TCDD inducible poly(ADP-ribose) polymerase 3 156673235-156706770 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA036796 Uncertain Approved Microtubules Breast cancer:2.00e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 232.4 Expressed in all +CCNL1 ania-6a ENSG00000163660 Cyclin L1 3 157146508-157160760 Predicted secreted proteins Evidence at protein level HPA057911 Supported Nucleoplasm
Nuclear bodies Urothelial cancer:6.96e-7 (favourable), Renal cancer:1.01e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 28.8 Expressed in all +PTX3 TNFAIP5, TSG-14 ENSG00000163661 Pentraxin 3 3 157436789-157443628 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA069320 Approved Endometrial cancer:8.35e-9 (unfavourable), Lung cancer:8.75e-6 (unfavourable), Head and neck cancer:6.36e-4 (unfavourable) Tissue enhanced Tissue enhanced adipose tissue: 164.6;appendix: 54.2 bone marrow: 52.6 Cell line enhanced ASC TERT1: 1187.1;HHSteC: 1837.3;HSkMC: 1660.2;hTEC/SVTERT24-B: 1235.3;TIME: 1387.2;U-2197: 1444.5 +HESX1 ANF, RPX ENSG00000163666 HESX homeobox 1 3 57197843-57226521 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024187 Approved Approved Nucleus Tissue enhanced Tissue enhanced testis: 12.4 skin: 5.4 Cell line enhanced NTERA-2: 73.5;U-266/84: 17.0 +DCLK3 DCAMKL3, DCDC3C, KIAA1765 ENSG00000163673 Doublecortin like kinase 3 3 36712422-36764349 Enzymes, Predicted membrane proteins Evidence at protein level HPA040685 Approved Tissue enhanced Tissue enhanced testis: 4.9 cerebral cortex: 1.1 Cell line enhanced SCLC-21H: 1.0 +SLMAP KIAA1601, SLAP ENSG00000163681 Sarcolemma associated protein 3 57755450-57929168 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002357, HPA002358 Enhanced Approved Endoplasmic reticulum Renal cancer:1.58e-6 (favourable), Lung cancer:7.98e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 265.6 Expressed in all +RPL9 L9 ENSG00000163682 Ribosomal protein L9 4 39454124-39458948 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003372 Approved Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:7.34e-4 (unfavourable) Expressed in all Expressed in all epididymis: 2710.2 Expressed in all +SMIM14 C4orf34, FLJ13289 ENSG00000163683 Small integral membrane protein 14 4 39546330-39639090 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051299 Uncertain Head and neck cancer:3.00e-6 (favourable), Renal cancer:2.07e-4 (favourable), Endometrial cancer:2.63e-4 (favourable), Liver cancer:3.47e-4 (favourable) Expressed in all Expressed in all liver: 54.3 Cell line enhanced Daudi: 189.5 +RPP14 P14 ENSG00000163684 Ribonuclease P/MRP subunit p14 3 58306247-58324695 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036194 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.07e-10 (favourable), Thyroid cancer:2.96e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 21.1 Expressed in all +ABHD6 ENSG00000163686 Abhydrolase domain containing 6 3 58237506-58295693 Enzymes, Predicted membrane proteins Evidence at protein level HPA017283, HPA073225 Uncertain Approved Nucleoplasm
Vesicles Renal cancer:1.11e-11 (favourable), Colorectal cancer:1.13e-4 (favourable) Expressed in all Mixed small intestine: 50.9 Mixed +DNASE1L3 DNAS1L3, LSD ENSG00000163687 Deoxyribonuclease 1 like 3 3 58192257-58214697 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA019955 Approved Renal cancer:1.06e-7 (favourable), Liver cancer:1.20e-6 (favourable) Mixed Tissue enhanced liver: 136.7;spleen: 316.5 tonsil: 51.2 Cell line enhanced BEWO: 1.8;RPMI-8226: 1.4 +C3orf67 FLJ42117, FLJ42930 ENSG00000163689 Chromosome 3 open reading frame 67 3 58717365-59050084 Predicted intracellular proteins Evidence at protein level HPA069696 Approved Golgi apparatus Mixed Tissue enhanced esophagus: 13.2;testis: 47.0 fallopian tube: 6.3 Mixed +RBM47 FLJ20273, NET18 ENSG00000163694 RNA binding motif protein 47 4 40423267-40630875 Predicted intracellular proteins Evidence at protein level HPA006347 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:3.33e-16 (favourable) Expressed in all Mixed small intestine: 71.5 Cell line enhanced BEWO: 135.3;CAPAN-2: 55.4 +APBB2 FE65L, FE65L1, MGC35575 ENSG00000163697 Amyloid beta precursor protein binding family B member 2 4 40810027-41216714 Predicted intracellular proteins Evidence at protein level HPA023542 Approved Approved Mitochondria Endometrial cancer:1.97e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 61.5 Cell line enhanced TIME: 151.9 +IL17RE FLJ23658 ENSG00000163701 Interleukin 17 receptor E 3 9902612-9916402 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA019011 Uncertain Expressed in all Mixed small intestine: 22.6 Cell line enhanced ASC TERT1: 27.7;BEWO: 14.7;T-47d: 18.4 +IL17RC IL17-RL ENSG00000163702 Interleukin 17 receptor C 3 9917074-9933630 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA019885, CAB026255 Approved Endometrial cancer:1.38e-4 (favourable) Expressed in all Expressed in all prostate: 24.2 Mixed +CRELD1 AVSD2 ENSG00000163703 Cysteine rich with EGF like domains 1 3 9933822-9945413 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026964 Uncertain Approved Nucleoli
Cytosol Glioma:6.05e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 65.6 Expressed in all +PRRT3 FLJ33674 ENSG00000163704 Proline rich transmembrane protein 3 3 9945542-9952394 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035127, HPA035128 Uncertain Approved Nucleus
Plasma membrane
Cytosol Mixed Tissue enhanced cerebral cortex: 19.4;parathyroid gland: 27.8 fallopian tube: 12.2 Cell line enhanced MCF7: 17.7;SK-BR-3: 25.1 +FANCD2OS C3orf24, MGC40179 ENSG00000163705 FANCD2 opposite strand 3 10081317-10108231 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 96 testis: 54.7 bone marrow: 0.5 Cell line enhanced CACO-2: 1.1 +PCOLCE2 PCPE2 ENSG00000163710 Procollagen C-endopeptidase enhancer 2 3 142815922-142889203 Predicted secreted proteins Evidence at protein level HPA013203 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.96e-5 (unfavourable), Urothelial cancer:1.08e-4 (unfavourable) Mixed Tissue enhanced adipose tissue: 81.7;placenta: 57.9 heart muscle: 42.3 Cell line enhanced ASC diff: 37.5;U-2197: 58.5;U-266/70: 47.2 +U2SURP fSAPa, SR140 ENSG00000163714 U2 snRNP associated SURP domain containing 3 142964497-143060546 Predicted intracellular proteins Evidence at protein level HPA037545, HPA037546, HPA061407 Enhanced Supported Nucleoplasm Renal cancer:8.86e-7 (unfavourable), Liver cancer:3.15e-5 (unfavourable), Urothelial cancer:6.78e-4 (favourable), Endometrial cancer:8.44e-4 (unfavourable), Pancreatic cancer:8.92e-4 (unfavourable) Expressed in all Expressed in all testis: 37.6 Expressed in all +MTMR14 C3orf29, FLJ22405, FLJ90311, hEDTP, hJumpy ENSG00000163719 Myotubularin related protein 14 3 9649433-9702393 Disease related genes, Predicted secreted proteins Evidence at protein level HPA054063 Approved Renal cancer:2.74e-4 (favourable), Liver cancer:3.95e-4 (unfavourable) Expressed in all Expressed in all lymph node: 41.8 Expressed in all +TTC14 FLJ00166, KIAA1980 ENSG00000163728 Tetratricopeptide repeat domain 14 3 180602130-180617828 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009295 Uncertain Supported Nucleus Expressed in all Expressed in all parathyroid gland: 60.8 Expressed in all +CXCL3 CINC-2b, GRO3, GROg, MIP-2b, SCYB3 ENSG00000163734 C-X-C motif chemokine ligand 3 4 74036589-74038807 Plasma proteins, Predicted secreted proteins Evidence at protein level Cervical cancer:2.33e-4 (unfavourable) Tissue enhanced Tissue enhanced adipose tissue: 26.9;cervix, uterine: 33.6 appendix: 20.3 Cell line enhanced BJ hTERT+: 39.2;hTEC/SVTERT24-B: 75.0;RPTEC TERT1: 32.7 +CXCL5 ENA-78, SCYB5 ENSG00000163735 C-X-C motif chemokine ligand 5 4 73995642-73998779 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA065474 Approved Renal cancer:2.45e-5 (unfavourable), Liver cancer:1.39e-4 (unfavourable), Pancreatic cancer:2.23e-4 (unfavourable), Cervical cancer:3.43e-4 (unfavourable) Tissue enhanced Tissue enhanced appendix: 47.7 urinary bladder: 15.5 Cell line enhanced A549: 165.3;EFO-21: 141.1;HSkMC: 77.3;hTEC/SVTERT24-B: 78.0;RPTEC TERT1: 436.4 +PPBP b-TG1, Beta-TG, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, NAP-2-L1, PBP, SCYB7, TGB, TGB1, THBGB1 ENSG00000163736 Pro-platelet basic protein 4 73987038-73988197 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA008354, CAB017624 Supported Cervical cancer:6.17e-4 (unfavourable) Tissue enriched Tissue enhanced bone marrow: 110.6 spleen: 24.3 Cell line enhanced HBEC3-KT: 1.6;HEL: 6.2;RPTEC TERT1: 1.1 +PF4 CXCL4, SCYB4 ENSG00000163737 Platelet factor 4 4 73981077-73982124 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB026008, HPA052485 Enhanced Tissue enhanced Group enriched 5 bone marrow: 53.7;spleen: 13.4 placenta: 6.5 Cell line enriched 13 HEL: 37.2 +MTHFD2L MGC72244 ENSG00000163738 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 4 74114174-74303099 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035434 Uncertain Mixed Mixed adrenal gland: 4.8 Mixed +CXCL1 FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1 ENSG00000163739 C-X-C motif chemokine ligand 1 4 73869393-73871242 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.60e-4 (unfavourable), Liver cancer:2.91e-4 (unfavourable), Cervical cancer:7.23e-4 (unfavourable), Breast cancer:7.83e-4 (favourable) Expressed in all Tissue enhanced cervix, uterine: 178.6;spleen: 112.8 urinary bladder: 92.0 Group enriched 7 BJ hTERT+: 658.8;EFO-21: 1914.4;RPTEC TERT1: 559.0 +RCHY1 ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363 ENSG00000163743 Ring finger and CHY zinc finger domain containing 1 4 75479037-75514764 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030339 Approved Supported Nucleoplasm
Cytosol Renal cancer:3.62e-5 (favourable), Urothelial cancer:7.89e-5 (favourable), Colorectal cancer:9.09e-4 (favourable) Expressed in all Expressed in all thyroid gland: 31.7 Expressed in all +PLSCR2 ENSG00000163746 Phospholipid scramblase 2 3 146391421-146495991 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 10 testis: 23.5 epididymis: 2.2 Not detected +CCDC158 FLJ25770 ENSG00000163749 Coiled-coil domain containing 158 4 76312997-76421868 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 27 testis: 60.4 thyroid gland: 2.2 Not detected +CPA3 ENSG00000163751 Carboxypeptidase A3 3 148865256-148897196 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA006479, HPA008689, CAB020712 Enhanced Mixed Tissue enhanced gallbladder: 173.9 lung: 126.9 Cell line enriched 46 HEL: 265.9 +GYG1 GYG ENSG00000163754 Glycogenin 1 3 148991341-149027668 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA030497 Approved Supported Vesicles Liver cancer:6.15e-5 (unfavourable) Expressed in all Expressed in all testis: 210.0 Mixed +HPS3 BLOC2S1, SUTAL ENSG00000163755 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 3 149129584-149173732 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046281, HPA052778 Approved Approved Golgi apparatus
Plasma membrane Renal cancer:4.38e-4 (unfavourable), Liver cancer:6.04e-4 (unfavourable) Expressed in all Mixed spleen: 22.0 Expressed in all +TM4SF18 L6D ENSG00000163762 Transmembrane 4 L six family member 18 3 149318498-149334414 Predicted membrane proteins, Transporters Evidence at transcript level HPA053639, HPA069378 Approved Uncertain Nucleoli
Vesicles Liver cancer:8.63e-4 (favourable) Expressed in all Mixed spleen: 47.0 Group enriched 6 A549: 86.7;EFO-21: 184.5;HUVEC TERT2: 55.1;NTERA-2: 47.1 +TOPBP1 KIAA0259, TOP2BP1 ENSG00000163781 Topoisomerase (DNA) II binding protein 1 3 133598175-133661893 Predicted intracellular proteins Evidence at protein level CAB022451, HPA036738, HPA036739 Approved Enhanced Nucleus Liver cancer:4.66e-5 (unfavourable), Endometrial cancer:5.76e-5 (unfavourable), Pancreatic cancer:1.88e-4 (unfavourable) Expressed in all Expressed in all testis: 54.2 Expressed in all +RYK D3S3195, JTK5, JTK5A, RYK1 ENSG00000163785 Receptor-like tyrosine kinase 3 134065303-134250744 Predicted membrane proteins Evidence at protein level CAB034117, HPA045503, HPA075430 Uncertain Approved Golgi apparatus
Cytosol Liver cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all ovary: 101.1 Expressed in all +SNRK FLJ20224, HSNFRK, KIAA0096 ENSG00000163788 SNF related kinase 3 43286512-43424764 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042163 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cell Junctions Renal cancer:9.41e-5 (favourable), Breast cancer:9.28e-4 (favourable) Expressed in all Expressed in all placenta: 47.8 Expressed in all +TCF23 bHLHa24, OUT ENSG00000163792 Transcription factor 23 2 27149004-27156974 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Tissue enhanced endometrium: 33.8;ovary: 22.7;smooth muscle: 30.8 fallopian tube: 13.9 Cell line enriched 7 THP-1: 2.3 +DNAJC5G CSP-gamma, FLJ40417 ENSG00000163793 DnaJ heat shock protein family (Hsp40) member C5 gamma 2 27275421-27281499 Predicted membrane proteins Evidence at transcript level HPA041445 Approved Not detected Group enriched 41 epididymis: 65.0;testis: 42.7 cerebral cortex: 1.3 Cell line enhanced HAP1: 1.0 +UCN UI, UROC ENSG00000163794 Urocortin 2 27307400-27308445 Predicted secreted proteins Evidence at protein level CAB010911 Approved Approved Endoplasmic reticulum Renal cancer:1.84e-7 (unfavourable), Colorectal cancer:8.10e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 2.8 Cell line enhanced U-266/70: 14.8 +ZNF513 FLJ32203, RP58 ENSG00000163795 Zinc finger protein 513 2 27377231-27380790 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051493 Uncertain Liver cancer:6.21e-5 (unfavourable) Expressed in all Expressed in all testis: 25.9 Expressed in all +SLC4A1AP HLC3, kanadaptin ENSG00000163798 Solute carrier family 4 member 1 adaptor protein 2 27663471-27694976 Predicted intracellular proteins, Transporters Evidence at protein level HPA036679 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Liver cancer:3.76e-7 (unfavourable), Endometrial cancer:1.49e-4 (unfavourable), Urothelial cancer:1.79e-4 (unfavourable) Expressed in all Expressed in all testis: 62.0 Expressed in all +PLB1 FLJ30866, PLB ENSG00000163803 Phospholipase B1 2 28457145-28643788 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014045 Approved Cytosol Mixed Group enriched 7 skin: 9.4;small intestine: 45.7 testis: 4.2 Cell line enhanced BEWO: 3.5 +SPDYA Ringo3, SPDY1, SPY1 ENSG00000163806 Speedy/RINGO cell cycle regulator family member A 2 28782517-28850611 Predicted intracellular proteins Evidence at protein level HPA035162, HPA066214 Enhanced Supported Nucleoplasm Not detected Tissue enriched 30 testis: 58.6 skin: 1.9 Mixed +KIAA1143 ENSG00000163807 KIAA1143 3 44737661-44761662 Predicted intracellular proteins Evidence at protein level HPA045018, HPA061799 Approved Approved Nucleus
Cytokinetic bridge Renal cancer:3.26e-6 (favourable), Colorectal cancer:3.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 15.0 Expressed in all +KIF15 HKLP2, KNSL7, NY-BR-62 ENSG00000163808 Kinesin family member 15 3 44761717-44873376 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035516, HPA035517 Approved Colorectal cancer:3.12e-4 (favourable) Mixed Tissue enhanced testis: 14.2 bone marrow: 3.1 Mixed +TGM4 TGP ENSG00000163810 Transglutaminase 4 3 44874608-44914990 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA032072, CAB033571 Enhanced Tissue enriched Tissue enriched 465 prostate: 689.9 adrenal gland: 1.4 Cell line enhanced BEWO: 4.7;NB-4: 1.7;RPMI-8226: 1.3;SH-SY5Y: 1.5 +WDR43 KIAA0007, NET12, UTP5 ENSG00000163811 WD repeat domain 43 2 28894643-28948222 Predicted intracellular proteins Evidence at protein level HPA044733 Uncertain Liver cancer:3.66e-5 (unfavourable), Endometrial cancer:5.70e-4 (unfavourable) Expressed in all Expressed in all testis: 36.5 Expressed in all +ZDHHC3 GODZ, ZNF373 ENSG00000163812 Zinc finger DHHC-type containing 3 3 44915257-44976185 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB012465, HPA016616 Approved Approved Golgi apparatus Renal cancer:1.81e-8 (favourable), Liver cancer:1.37e-4 (unfavourable), Colorectal cancer:3.43e-4 (favourable) Expressed in all Expressed in all skin,testis: 65.5 Expressed in all +CDCP1 CD318, SIMA135 ENSG00000163814 CUB domain containing protein 1 3 45082278-45146422 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010978, HPA010979, CAB025637 Enhanced Lung cancer:1.41e-5 (unfavourable), Pancreatic cancer:1.48e-4 (unfavourable) Expressed in all Mixed skin: 27.7 Cell line enhanced hTEC/SVTERT24-B: 263.4;hTERT-HME1: 135.9 +CLEC3B TN, TNA ENSG00000163815 C-type lectin domain family 3 member B 3 45001548-45036071 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002582, HPA034794 Approved Liver cancer:9.99e-9 (favourable), Head and neck cancer:1.53e-4 (favourable), Pancreatic cancer:5.68e-4 (favourable) Expressed in all Tissue enhanced spleen: 303.3 adipose tissue: 203.9 Cell line enhanced ASC diff: 169.4;ASC TERT1: 341.9;U-2197: 94.5 +SLC6A20 XT3, Xtrp3 ENSG00000163817 Solute carrier family 6 member 20 3 45755450-45796535 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA029873 Uncertain Renal cancer:1.55e-5 (favourable) Mixed Tissue enhanced duodenum: 24.4;small intestine: 19.3 gallbladder: 10.9 Cell line enhanced HaCaT: 1.5 +LZTFL1 BBS17 ENSG00000163818 Leucine zipper transcription factor like 1 3 45823316-45916042 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043466, HPA048447 Enhanced Supported Cytosol Expressed in all Mixed testis: 35.9 Mixed +FYCO1 FLJ13335, ZFYVE7 ENSG00000163820 FYVE and coiled-coil domain containing 1 3 45917899-45995824 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035526, HPA057966 Uncertain Enhanced Vesicles Renal cancer:3.33e-11 (favourable) Expressed in all Expressed in all skeletal muscle: 91.9 Expressed in all +CCR1 CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1 ENSG00000163823 C-C motif chemokine receptor 1 3 46201709-46208396 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Renal cancer:1.01e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 57.5 spleen: 41.1 Cell line enhanced Karpas-707: 230.1;RPMI-8226: 105.8;U-266/84: 123.3 +RTP3 LTM1, TMEM7, Z3CXXC3 ENSG00000163825 Receptor transporter protein 3 3 46497491-46500949 Predicted membrane proteins Evidence at protein level HPA075932 Uncertain Mitochondria Liver cancer:3.11e-6 (favourable) Group enriched Tissue enriched 24 liver: 33.8 testis: 1.4 Cell line enriched 11 SiHa: 10.7 +LRRC2 ENSG00000163827 Leucine rich repeat containing 2 3 46515423-46580099 Predicted intracellular proteins Evidence at protein level HPA039138, HPA040096 Approved Tissue enhanced Group enriched 5 heart muscle: 30.0;skeletal muscle: 55.9;thyroid gland: 37.0 endometrium: 7.8 Cell line enhanced fHDF/TERT166: 5.6;HEL: 3.8;LHCN-M2: 3.4 +ELP6 C3orf75, FLJ20211, TMEM103 ENSG00000163832 Elongator acetyltransferase complex subunit 6 3 47495640-47513761 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046358, HPA064545 Uncertain Approved Nucleus
Centrosome
Cytosol Renal cancer:3.42e-6 (favourable) Expressed in all Expressed in all testis: 32.0 Expressed in all +FBXO40 Fbx40, KIAA1195 ENSG00000163833 F-box protein 40 3 121593119-121630295 Plasma proteins, Predicted intracellular proteins Evidence at protein level Not detected Group enriched 36 heart muscle: 56.2;skeletal muscle: 54.0 prostate: 1.5 Not detected +DTX3L BBAP ENSG00000163840 Deltex E3 ubiquitin ligase 3L 3 122564238-122575203 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010570 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:8.99e-4 (unfavourable) Expressed in all Expressed in all spleen: 36.1 Cell line enhanced BJ hTERT+ SV40 Large T+: 83.9;BJ hTERT+ SV40 Large T+ RasG12V: 107.7 +ZNF148 BERF-1, BFCOL1, HT-BETA, pHZ-52, ZBP-89, ZFP148 ENSG00000163848 Zinc finger protein 148 3 125225561-125375354 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001656, CAB017486 Supported Supported Nucleus
Golgi apparatus Pancreatic cancer:2.88e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 50.4 Expressed in all +NMNAT3 PNAT3 ENSG00000163864 Nicotinamide nucleotide adenylyltransferase 3 3 139560180-139678017 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039077, HPA057402 Approved Supported Mitochondria Renal cancer:1.95e-5 (favourable), Pancreatic cancer:7.29e-5 (favourable), Cervical cancer:9.67e-4 (favourable) Mixed Mixed ovary: 20.5 Cell line enhanced HEL: 22.9;THP-1: 8.5;U-266/70: 11.9 +SMIM12 C1orf212, FLJ90372 ENSG00000163866 Small integral membrane protein 12 1 34712737-34859816 Predicted membrane proteins Evidence at protein level HPA065331 Approved Approved Mitochondria Renal cancer:1.15e-5 (favourable), Liver cancer:1.18e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 45.3 Expressed in all +ZMYM6 Buster2, MYM, ZBED7, ZNF198L4, ZNF258 ENSG00000163867 Zinc finger MYM-type containing 6 1 34986165-35031968 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011004, HPA071865 Approved Supported Nucleoplasm Breast cancer:1.30e-5 (favourable) Expressed in all Mixed testis: 19.0 Expressed in all +TPRA1 FLJ32197, GPR175, TMEM227, TPRA40 ENSG00000163870 Transmembrane protein adipocyte associated 1 3 127573069-127598251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019784 Approved Approved Vesicles Liver cancer:6.46e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 38.5 Expressed in all +YEATS2 FLJ10201, FLJ12841, FLJ13308, KIAA1197 ENSG00000163872 YEATS domain containing 2 3 183697818-183812625 Predicted intracellular proteins Evidence at protein level HPA045891 Uncertain Approved Nucleoplasm Renal cancer:6.90e-9 (unfavourable), Liver cancer:4.82e-6 (unfavourable) Expressed in all Mixed cerebral cortex: 19.5 Expressed in all +GRIK3 GluK3, GLUR7 ENSG00000163873 Glutamate ionotropic receptor kainate type subunit 3 1 36795527-37034129 Plasma proteins, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enriched 6 cerebral cortex: 19.8 seminal vesicle: 3.5 Group enriched 5 SCLC-21H: 11.4;T-47d: 37.2 +ZC3H12A FLJ23231, MCPIP1 ENSG00000163874 Zinc finger CCCH-type containing 12A 1 37474552-37484379 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA032052, HPA032053 Uncertain Supported Nucleoplasm
Cytoplasmic bodies Renal cancer:5.95e-5 (unfavourable), Endometrial cancer:9.67e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 84.3 gallbladder: 55.5 Cell line enhanced RT4: 48.1 +MEAF6 C1orf149, CENP-28, Eaf6, FLJ11730, NY-SAR-91 ENSG00000163875 MYST/Esa1 associated factor 6 1 37492575-37514774 Disease related genes, Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all prostate: 139.9 Expressed in all +SNIP1 ENSG00000163877 Smad nuclear interacting protein 1 1 37534449-37554344 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036896 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Mixed testis: 7.6 Expressed in all +DNALI1 dJ423B22.5, hp28, P28 ENSG00000163879 Dynein axonemal light intermediate chain 1 1 37556919-37566857 Predicted intracellular proteins Evidence at protein level HPA028305 Approved Lung cancer:6.02e-4 (favourable) Mixed Tissue enhanced fallopian tube: 86.2 testis: 38.3 Cell line enhanced AF22: 13.9;RPTEC TERT1: 12.6;SH-SY5Y: 12.3;T-47d: 28.1 +POLR2H RPB8 ENSG00000163882 RNA polymerase II subunit H 3 184361718-184368596 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA037745, HPA055813 Enhanced Supported Nucleus Renal cancer:1.65e-10 (unfavourable), Liver cancer:2.01e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 71.8 Expressed in all +KLF15 KKLF ENSG00000163884 Kruppel like factor 15 3 126342635-126357442 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028866 Uncertain Renal cancer:3.27e-7 (favourable) Tissue enhanced Tissue enhanced ovary: 42.8 adipose tissue: 37.0 Cell line enhanced ASC diff: 38.8;HHSteC: 28.8 +CFAP100 CCDC37, FLJ40083, MIA1 ENSG00000163885 Cilia and flagella associated protein 100 3 126394939-126436556 Predicted intracellular proteins Evidence at protein level HPA046354 Enhanced Tissue enhanced Group enriched 5 fallopian tube: 43.4;testis: 34.5 lung: 7.4 Not detected +CAMK2N2 CaM-KIIN ENSG00000163888 Calcium/calmodulin dependent protein kinase II inhibitor 2 3 184259213-184261463 Predicted intracellular proteins Evidence at protein level HPA050835 Supported Nucleus
Centrosome Cervical cancer:9.77e-4 (favourable) Mixed Tissue enhanced adrenal gland: 12.2;cerebral cortex: 40.4 pancreas: 5.6 Cell line enhanced REH: 28.6;SCLC-21H: 37.1;U-138 MG: 32.1 +LIPH LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B ENSG00000163898 Lipase H 3 185506262-185552613 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049079 Approved Renal cancer:9.20e-5 (favourable), Thyroid cancer:4.21e-4 (favourable), Pancreatic cancer:4.59e-4 (unfavourable), Endometrial cancer:9.40e-4 (unfavourable) Mixed Tissue enhanced rectum: 40.8;stomach: 45.0 colon: 35.7 Cell line enhanced CAPAN-2: 65.0;RPTEC TERT1: 28.0;T-47d: 16.5 +TMEM41A MGC15397 ENSG00000163900 Transmembrane protein 41A 3 185476496-185499057 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059101, HPA059790 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Endometrial cancer:6.70e-6 (unfavourable), Liver cancer:1.04e-4 (unfavourable), Pancreatic cancer:4.72e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 28.2 Expressed in all +RPN1 OST1 ENSG00000163902 Ribophorin I 3 128619970-128681075 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB009748, HPA026828, HPA051520 Enhanced Enhanced Endoplasmic reticulum Liver cancer:4.80e-4 (unfavourable) Expressed in all Expressed in all epididymis: 422.3 Expressed in all +SENP2 AXAM2, DKFZp762A2316, KIAA1331, SMT3IP2 ENSG00000163904 SUMO1/sentrin/SMT3 specific peptidase 2 3 185582496-185633551 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA029247, HPA029248 Approved Supported Cytosol Endometrial cancer:7.98e-5 (unfavourable) Expressed in all Expressed in all testis: 26.9 Expressed in all +HEYL bHLHb33, HESR3, HEY3 ENSG00000163909 Hes related family bHLH transcription factor with YRPW motif-like 1 39624153-39639945 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001438, HPA076960 Approved Approved Mitochondria
Cytosol Renal cancer:2.26e-6 (unfavourable), Urothelial cancer:2.63e-5 (unfavourable), Stomach cancer:3.57e-4 (unfavourable) Expressed in all Mixed placenta: 44.4 Cell line enhanced LHCN-M2: 18.5;RH-30: 26.3 +IFT122 SPG, WDR10, WDR10p, WDR140 ENSG00000163913 Intraflagellar transport 122 3 129440036-129520507 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041815 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 147.4 Expressed in all +RHO CSNBAD1, OPN2, RP4 ENSG00000163914 Rhodopsin 3 129528640-129535169 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA013440, CAB022486, CAB034887, CAB034888 Supported Not detected Not detected cerebral cortex: 0.3 Not detected +RFC4 A1, RFC37 ENSG00000163918 Replication factor C subunit 4 3 186789880-186807058 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004557, HPA049123, HPA058507 Enhanced Enhanced Nucleoplasm Renal cancer:2.22e-16 (unfavourable), Liver cancer:6.75e-7 (unfavourable), Cervical cancer:7.41e-5 (favourable), Pancreatic cancer:7.38e-4 (unfavourable) Expressed in all Expressed in all testis: 40.7 Expressed in all +RPL39L RPL39L1 ENSG00000163923 Ribosomal protein L39 like 3 187120948-187180908 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047105 Approved Glioma:9.50e-7 (unfavourable), Ovarian cancer:1.94e-4 (favourable), Endometrial cancer:6.05e-4 (unfavourable) Expressed in all Tissue enriched 15 testis: 220.3 breast: 14.6 Mixed +BAP1 hucep-6, KIAA0272, UCHL2 ENSG00000163930 BRCA1 associated protein 1 3 52401013-52410350 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004322, HPA028814, HPA028815, HPA055560 Approved Enhanced Nucleoplasm
Cytosol Renal cancer:3.29e-7 (favourable) Expressed in all Expressed in all testis: 118.2 Expressed in all +TKT ENSG00000163931 Transketolase 3 53224707-53256052 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029480, HPA029481 Enhanced Enhanced Nucleoplasm Liver cancer:7.21e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 431.3 Expressed in all +PRKCD ENSG00000163932 Protein kinase C delta 3 53156009-53192717 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001863, HPA001890, CAB010469, CAB013225 Enhanced Enhanced Endoplasmic reticulum
Golgi apparatus
Cytosol Liver cancer:2.24e-4 (unfavourable), Lung cancer:9.01e-4 (favourable) Expressed in all Mixed adrenal gland: 70.4 Expressed in all +RFT1 CDG1N ENSG00000163933 RFT1 homolog 3 53088483-53130462 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA060327, HPA069022 Approved Approved Vesicles Liver cancer:1.69e-4 (unfavourable) Expressed in all Expressed in all testis: 25.8 Expressed in all +SFMBT1 DKFZp434L243, RU1, SFMBT ENSG00000163935 Scm-like with four mbt domains 1 3 52903572-53046750 Predicted intracellular proteins Evidence at protein level HPA036152, HPA064564 Enhanced Nucleoplasm Endometrial cancer:3.86e-4 (unfavourable) Expressed in all Group enriched 6 parathyroid gland: 32.9;testis: 83.1 thyroid gland: 9.9 Expressed in all +GNL3 C77032, E2IG3, MGC800, NS ENSG00000163938 G protein nucleolar 3 3 52681156-52694492 Predicted intracellular proteins Evidence at protein level CAB020770, HPA036742, HPA036743 Enhanced Enhanced Nucleoli
Nuclear bodies Renal cancer:5.69e-5 (unfavourable), Liver cancer:2.93e-4 (unfavourable), Prostate cancer:6.11e-4 (unfavourable) Expressed in all Expressed in all breast: 78.5 Expressed in all +PBRM1 BAF180, PB1 ENSG00000163939 Polybromo 1 3 52545352-52685917 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015629, HPA059373 Uncertain Supported Nucleoplasm Expressed in all Expressed in all thyroid gland: 44.7 Expressed in all +UVSSA KIAA1530 ENSG00000163945 UV stimulated scaffold protein A 4 1347266-1388049 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050824, HPA053496 Approved Approved Nucleoplasm Renal cancer:1.90e-4 (unfavourable), Urothelial cancer:6.87e-4 (favourable) Expressed in all Mixed testis: 12.2 Expressed in all +FAM208A C3orf63, KIAA1105, RAP140, se89-1, TASOR ENSG00000163946 Family with sequence similarity 208 member A 3 56620133-56683237 Predicted intracellular proteins Evidence at protein level HPA006735, HPA017142 Uncertain Enhanced Nucleoplasm Expressed in all Mixed testis: 53.5 Expressed in all +ARHGEF3 DKFZP434F2429, GEF3, STA3, XPLN ENSG00000163947 Rho guanine nucleotide exchange factor 3 3 56727418-57079329 Predicted intracellular proteins Evidence at protein level HPA034715, HPA064945 Uncertain Approved Cytosol Renal cancer:1.96e-7 (favourable), Endometrial cancer:2.17e-4 (favourable), Head and neck cancer:2.61e-4 (favourable) Expressed in all Expressed in all endometrium: 64.9 Cell line enhanced Hep G2: 60.0;RPMI-8226: 63.7 +SLBP HBP ENSG00000163950 Stem-loop binding protein 4 1692800-1712555 Predicted intracellular proteins Evidence at protein level HPA019254, HPA061670 Enhanced Supported Nucleus
Nucleoli
Cytosol Liver cancer:2.29e-5 (unfavourable) Expressed in all Expressed in all testis: 130.6 Expressed in all +LRPAP1 A2MRAP, HBP44 ENSG00000163956 LDL receptor related protein associated protein 1 4 3506376-3532559 Disease related genes, Predicted secreted proteins Evidence at protein level HPA008001, CAB025518 Enhanced Supported Enhanced Endoplasmic reticulum Renal cancer:4.67e-11 (favourable) Expressed in all Expressed in all placenta: 13.7 Expressed in all +ZDHHC19 MGC33345 ENSG00000163958 Zinc finger DHHC-type containing 19 3 196197449-196211437 Enzymes, Predicted membrane proteins Evidence at transcript level Mixed Tissue enriched 44 testis: 29.2 adrenal gland: 0.6 Not detected +SLC51A OSTalpha ENSG00000163959 Solute carrier family 51 alpha subunit 3 196211487-196243178 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA039123 Enhanced Liver cancer:7.54e-4 (favourable) Tissue enriched Tissue enhanced duodenum: 29.3;liver: 35.1;small intestine: 71.3 colon: 9.9 Cell line enhanced REH: 3.4 +UBXN7 KIAA0794, UBXD7 ENSG00000163960 UBX domain protein 7 3 196347662-196432474 Predicted intracellular proteins Evidence at protein level HPA048441, HPA049442 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 22.2 Expressed in all +RNF168 FLJ35794 ENSG00000163961 Ring finger protein 168 3 196468783-196503768 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046109 Enhanced Nucleoplasm
Nuclear bodies Liver cancer:2.29e-4 (unfavourable), Cervical cancer:8.21e-4 (favourable), Pancreatic cancer:8.31e-4 (unfavourable) Expressed in all Mixed testis: 20.0 Expressed in all +PIGX FLJ20522 ENSG00000163964 Phosphatidylinositol glycan anchor biosynthesis class X 3 196639775-196736007 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029409 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:7.45e-5 (unfavourable), Cervical cancer:2.12e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 39.5 Expressed in all +MELTF CD228, FLJ38863, MAP97, MFI2, MGC4856, MTf, MTF1 ENSG00000163975 Melanotransferrin 3 196988621-197029816 CD markers, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA004880 Approved Renal cancer:6.99e-11 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 32.3;salivary gland: 28.2 small intestine: 9.6 Cell line enhanced A-431: 140.8;SK-MEL-30: 152.3 +OTOP1 ENSG00000163982 Otopetrin 1 4 4188803-4226889 Predicted membrane proteins Evidence at transcript level HPA035599 Uncertain Not detected Not detected skin: 0.2 Not detected +S100P ENSG00000163993 S100 calcium binding protein P 4 6693069-6697170 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019502 Enhanced Supported Nuclear bodies Pancreatic cancer:2.00e-4 (unfavourable) Tissue enhanced Tissue enhanced bone marrow: 169.5;stomach: 363.3;urinary bladder: 178.9 placenta: 130.7 Cell line enhanced BEWO: 180.4;Hep G2: 139.7;hTCEpi: 158.3;RT4: 329.6;SK-BR-3: 170.0 +ABLIM2 KIAA1808 ENSG00000163995 Actin binding LIM protein family member 2 4 7965310-8158832 Predicted intracellular proteins Evidence at protein level HPA035808 Uncertain Approved Nucleoplasm
Mitochondria Mixed Tissue enhanced skeletal muscle: 37.5;spleen: 28.4 cerebral cortex: 22.1 Group enriched 6 SCLC-21H: 16.3;SiHa: 6.6;U-2197: 19.7 +EXO5 C1orf176, DEM1, FLJ21144 ENSG00000164002 Exonuclease 5 1 40508741-40516556 Predicted intracellular proteins Evidence at protein level HPA028429 Supported Nucleoplasm
Cytosol Liver cancer:9.16e-6 (unfavourable), Prostate cancer:2.93e-4 (unfavourable) Expressed in all Mixed smooth muscle: 11.3 Cell line enhanced THP-1: 101.0 +CLDN19 ENSG00000164007 Claudin 19 1 42733093-42740254 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Tissue enhanced Group enriched 12 kidney: 19.7;placenta: 14.5 breast: 1.4 Cell line enhanced CACO-2: 2.4;Hep G2: 4.3 +C1orf50 MGC955 ENSG00000164008 Chromosome 1 open reading frame 50 1 42767269-42775747 Predicted intracellular proteins Evidence at protein level HPA030236 Uncertain Melanoma:4.65e-4 (unfavourable) Expressed in all Expressed in all testis: 21.6 Expressed in all +ERMAP BTN5, RD, SC ENSG00000164010 Erythroblast membrane associated protein (Scianna blood group) 1 42817124-42844989 Blood group antigen proteins, Predicted membrane proteins Evidence at protein level HPA042573 Uncertain Expressed in all Mixed thyroid gland: 18.7 Cell line enhanced HEL: 31.0 +ZNF691 Zfp691 ENSG00000164011 Zinc finger protein 691 1 42846573-42852477 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA062527 Approved Approved Nucleus
Nucleoli
Vesicles Liver cancer:7.33e-6 (unfavourable), Pancreatic cancer:6.25e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 21.5 Expressed in all +AIMP1 EMAP-2, EMAPII, p43, SCYE1 ENSG00000164022 Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 4 106315544-106349226 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB017618, HPA018476 Supported Enhanced Cytosol Head and neck cancer:1.54e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 63.2 Expressed in all +SGMS2 MGC26963, SMS2 ENSG00000164023 Sphingomyelin synthase 2 4 107824563-107915047 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015076 Enhanced Renal cancer:1.37e-4 (favourable) Expressed in all Mixed gallbladder: 64.4 Mixed +METAP1 KIAA0094, MAP1A, MetAP1A ENSG00000164024 Methionyl aminopeptidase 1 4 98995620-99062813 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB025485, HPA037997, HPA037998 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:2.28e-5 (unfavourable), Liver cancer:3.08e-5 (unfavourable), Renal cancer:1.72e-4 (favourable), Colorectal cancer:7.22e-4 (favourable), Urothelial cancer:9.31e-4 (favourable) Expressed in all Expressed in all testis: 77.3 Expressed in all +DNAJB14 FLJ14281 ENSG00000164031 DnaJ heat shock protein family (Hsp40) member B14 4 99896248-99946726 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036016 Approved Renal cancer:2.12e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 34.7 Expressed in all +H2AFZ H2A.Z, H2AZ ENSG00000164032 H2A histone family member Z 4 99948086-99950388 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022549, HPA057236 Supported Supported Nucleoplasm Renal cancer:2.16e-6 (unfavourable), Liver cancer:1.02e-5 (unfavourable) Expressed in all Expressed in all lymph node: 349.5 Expressed in all +EMCN MUC14 ENSG00000164035 Endomucin 4 100395341-100880126 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005928 Approved Liver cancer:1.03e-4 (favourable), Renal cancer:2.25e-4 (favourable) Expressed in all Mixed kidney: 83.7 Cell line enriched 6 HUVEC TERT2: 25.7 +SLC9B1 NHA1, NHEDC1 ENSG00000164037 Solute carrier family 9 member B1 4 102885048-103019739 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA058971, HPA065520 Supported Microtubule organizing center
Mitochondria Mixed Tissue enriched 28 testis: 72.9 epididymis: 2.6 Mixed +SLC9B2 FLJ23984, NHA2, NHEDC2 ENSG00000164038 Solute carrier family 9 member B2 4 103019868-103085829 Predicted membrane proteins, Transporters Evidence at protein level HPA047008 Uncertain Approved Nucleoplasm
Cell Junctions Expressed in all Tissue enhanced cerebral cortex: 32.5 liver: 20.4 Mixed +BDH2 DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308 ENSG00000164039 3-hydroxybutyrate dehydrogenase 2 4 103079435-103099883 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036028, HPA036029 Enhanced Supported Cytosol Renal cancer:4.45e-13 (favourable), Lung cancer:1.20e-4 (favourable), Endometrial cancer:5.21e-4 (favourable), Thyroid cancer:7.75e-4 (favourable) Expressed in all Expressed in all kidney: 456.2 Expressed in all +PGRMC2 DG6, PMBP ENSG00000164040 Progesterone receptor membrane component 2 4 128269237-128288829 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041172, HPA058652 Approved Approved Nuclear bodies
Plasma membrane
Cytosol Endometrial cancer:3.62e-4 (favourable), Renal cancer:9.60e-4 (favourable) Expressed in all Expressed in all small intestine: 133.4 Expressed in all +CDC25A ENSG00000164045 Cell division cycle 25A 3 48157146-48188402 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005855 Approved Nucleus
Golgi apparatus
Vesicles Tissue enhanced Tissue enhanced testis: 24.4 bone marrow: 9.3 Expressed in all +CAMP CAP18, FALL-39, FALL39, LL37 ENSG00000164047 Cathelicidin antimicrobial peptide 3 48223347-48225491 Predicted secreted proteins Evidence at protein level CAB015949, CAB016522, HPA029874 Enhanced Cervical cancer:5.73e-4 (favourable) Tissue enhanced Group enriched 101 bone marrow: 1341.0;epididymis: 330.5 lymph node: 8.2 Group enriched 12 Daudi: 18.4;hTCEpi: 12.5;U-698: 50.9 +ZNF589 SZF1 ENSG00000164048 Zinc finger protein 589 3 48241100-48299253 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003145 Uncertain Approved Nucleoplasm Lung cancer:6.45e-5 (favourable), Pancreatic cancer:1.21e-4 (favourable), Head and neck cancer:1.71e-4 (favourable), Cervical cancer:2.50e-4 (favourable) Expressed in all Mixed prostate: 28.0 Expressed in all +FBXW12 Fbw12, FBXO35 ENSG00000164049 F-box and WD repeat domain containing 12 3 48372219-48401259 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA037491, HPA037492 Uncertain Not detected Tissue enhanced pancreas: 1.2;testis: 1.0 cerebral cortex: 0.2 Not detected +PLXNB1 KIAA0407, PLXN5, SEP ENSG00000164050 Plexin B1 3 48403854-48430051 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA040586 Enhanced Renal cancer:2.77e-5 (favourable), Head and neck cancer:5.03e-4 (favourable), Urothelial cancer:7.60e-4 (favourable) Expressed in all Mixed fallopian tube: 36.7 Mixed +CCDC51 FLJ12436 ENSG00000164051 Coiled-coil domain containing 51 3 48432164-48440456 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010980, HPA011408 Supported Supported Nucleoplasm
Centrosome
Mitochondria Expressed in all Mixed thyroid gland: 17.3 Expressed in all +ATRIP FLJ12343, MGC20625, MGC21482, MGC26740 ENSG00000164053 ATR interacting protein 3 48446710-48465716 Predicted intracellular proteins Evidence at protein level CAB033109, HPA047590 Approved Supported Nucleus Not detected Tissue enhanced testis: 30.8 thyroid gland: 10.5 Expressed in all +SHISA5 hShisa5, SCOTIN ENSG00000164054 Shisa family member 5 3 48467798-48504826 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042295 Approved Liver cancer:3.72e-6 (unfavourable), Renal cancer:8.64e-5 (unfavourable) Expressed in all Expressed in all placenta: 199.1 Expressed in all +SPRY1 hSPRY1 ENSG00000164056 Sprouty RTK signaling antagonist 1 4 123396795-123403760 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013538, HPA051369, HPA070554 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all Expressed in all gallbladder: 132.0 Cell line enhanced AF22: 94.2;AN3-CA: 180.0 +BSN ZNF231 ENSG00000164061 Bassoon presynaptic cytomatrix protein 3 49554489-49671545 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034757 Approved Mixed Tissue enriched 7 cerebral cortex: 28.2 testis: 4.2 Cell line enhanced K-562: 1.7;SCLC-21H: 5.1;SH-SY5Y: 2.9 +APEH D3F15S2, D3S48E, DNF15S2 ENSG00000164062 Acylaminoacyl-peptide hydrolase 3 49674002-49683963 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029700, HPA029701, HPA029702, HPA029703 Enhanced Enhanced Cytosol Renal cancer:3.32e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 101.6 Expressed in all +INTU KIAA1284, PDZD6, PDZK6 ENSG00000164066 Inturned planar cell polarity protein 4 127623271-127726737 Predicted intracellular proteins Evidence at protein level HPA036714, HPA036715 Enhanced Approved Vesicles Mixed Mixed epididymis: 6.4 Mixed +RNF123 FLJ12565, KPC1 ENSG00000164068 Ring finger protein 123 3 49689499-49721529 Enzymes, Predicted intracellular proteins Evidence at protein level HPA065983, HPA071879 Approved Approved Cytosol Renal cancer:1.33e-8 (favourable) Expressed in all Expressed in all skeletal muscle: 53.1 Expressed in all +HSPA4L APG-1, HSPH3, Osp94 ENSG00000164070 Heat shock protein family A (Hsp70) member 4 like 4 127781821-127840733 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034450, HPA039149, HPA061446 Enhanced Approved Centrosome
Cytosol Renal cancer:3.80e-9 (favourable), Urothelial cancer:6.78e-4 (unfavourable) Mixed Tissue enriched 8 testis: 193.3 parathyroid gland: 24.0 Cell line enhanced HAP1: 84.6 +MFSD8 CLN7, MGC33302 ENSG00000164073 Major facilitator superfamily domain containing 8 4 127917805-127965995 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA044802 Approved Supported Nucleoplasm
Vesicles Urothelial cancer:2.21e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 12.5 Mixed +ABHD18 C4orf29, FLJ21106 ENSG00000164074 Abhydrolase domain containing 18 4 127965306-128039711 Predicted intracellular proteins Evidence at protein level HPA050168, HPA051676 Approved Approved Nuclear membrane Colorectal cancer:5.35e-4 (favourable), Urothelial cancer:9.13e-4 (favourable) Expressed in all Expressed in all heart muscle: 11.0 Expressed in all +CAMKV MGC8407, VACAMKL ENSG00000164076 CaM kinase like vesicle associated 3 49857988-49870222 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007656, CAB034931 Enhanced Approved Nucleoplasm
Cytokinetic bridge Group enriched Tissue enriched 55 cerebral cortex: 86.2 testis: 1.5 Cell line enhanced AF22: 6.4;HAP1: 8.9;NTERA-2: 30.7;SCLC-21H: 12.2;SH-SY5Y: 7.1 +MON1A MGC13272, SAND1 ENSG00000164077 MON1 homolog A, secretory trafficking associated 3 49908862-49930173 Predicted intracellular proteins Evidence at protein level HPA053752, HPA058032 Uncertain Approved Cytosol Pancreatic cancer:3.30e-4 (favourable) Expressed in all Mixed duodenum: 14.5 Expressed in all +MST1R CD136, CDw136, PTK8, RON ENSG00000164078 Macrophage stimulating 1 receptor 3 49887002-49903873 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007657, HPA008180, CAB008972 Enhanced Approved Cytosol Urothelial cancer:2.33e-5 (favourable) Mixed Tissue enhanced skin: 69.4 stomach: 37.2 Cell line enhanced CAPAN-2: 84.1;HaCaT: 46.9;HBEC3-KT: 41.5;hTCEpi: 57.4;RT4: 49.8 +RAD54L2 ARIP4, KIAA0809, SRISNF2L ENSG00000164080 RAD54-like 2 (S. cerevisiae) 3 51541144-51668667 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035004, HPA039992 Supported Nucleus
Cytosol Renal cancer:1.71e-5 (favourable) Expressed in all Expressed in all testis: 8.8 Expressed in all +TEX264 FLJ13935, ZSIG11 ENSG00000164081 Testis expressed 264 3 51662693-51704323 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB005002, HPA017739 Enhanced Supported Nucleoli
Cytosol Renal cancer:7.95e-9 (favourable), Pancreatic cancer:5.67e-4 (favourable) Expressed in all Expressed in all testis: 113.1 Expressed in all +GRM2 GPRC1B, mGlu2, MGLUR2 ENSG00000164082 Glutamate metabotropic receptor 2 3 51707070-51718613 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA027868, HPA065166 Approved Supported Tissue enhanced Tissue enriched 10 cerebral cortex: 4.4 testis: 0.4 Cell line enriched 7 SCLC-21H: 7.3 +DUSP7 MKP-X, PYST2 ENSG00000164086 Dual specificity phosphatase 7 3 52048919-52056550 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:8.84e-6 (unfavourable) Expressed in all Expressed in all skin: 45.1 Expressed in all +POC1A DKFZP434C245, WDR51A ENSG00000164087 POC1 centriolar protein A 3 52075253-52154690 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040600 Approved Renal cancer:9.43e-7 (unfavourable), Pancreatic cancer:1.76e-4 (unfavourable), Colorectal cancer:1.78e-4 (favourable) Expressed in all Tissue enhanced testis: 23.1 bone marrow: 7.0 Expressed in all +PPM1M FLJ32332, PP2Ceta ENSG00000164088 Protein phosphatase, Mg2+/Mn2+ dependent 1M 3 52245793-52250597 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036905, HPA062291 Uncertain Approved Nuclear bodies Renal cancer:1.61e-5 (unfavourable), Lung cancer:6.69e-4 (favourable), Cervical cancer:7.73e-4 (favourable) Expressed in all Expressed in all lung: 35.0 Mixed +ETNPPL AGXT2L1 ENSG00000164089 Ethanolamine-phosphate phospho-lyase 4 108742040-108763054 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044546, HPA072938 Approved Approved Nucleus Glioma:1.31e-4 (favourable) Group enriched Group enriched 8 cerebral cortex: 141.2;liver: 98.6 stomach: 15.2 Cell line enhanced HeLa: 3.8;Hep G2: 1.5;NTERA-2: 1.1 +WDR82 MST107, MSTP107, PRO2730, PRO34047, SWD2, TMEM113, WDR82A ENSG00000164091 WD repeat domain 82 3 52254421-52288020 Predicted intracellular proteins Evidence at protein level HPA040427 Approved Nucleoli Expressed in all Expressed in all endometrium: 93.6 Expressed in all +PITX2 ARP1, Brx1, IGDS, IHG2, IRID2, Otlx2, RGS, RIEG, RIEG1, RS ENSG00000164093 Paired like homeodomain 2 4 110617423-110642123 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050074, HPA062728 Enhanced Nucleus Mixed Tissue enhanced placenta: 72.2 skeletal muscle: 18.3 Cell line enhanced CACO-2: 23.3;LHCN-M2: 25.4;RH-30: 24.6 +C4orf3 HCVFTP1 ENSG00000164096 Chromosome 4 open reading frame 3 4 119296419-119304445 Predicted membrane proteins Evidence at protein level HPA026907 Approved Approved Endoplasmic reticulum Renal cancer:3.46e-4 (favourable) Expressed in all Expressed in all esophagus: 150.6 Expressed in all +PRSS12 BSSP-3, MRT1 ENSG00000164099 Protease, serine 12 4 118280038-118353003 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA035054, HPA035055 Uncertain Approved Nucleus
Actin filaments Head and neck cancer:1.03e-4 (favourable), Glioma:1.53e-4 (favourable) Mixed Mixed cervix, uterine: 22.4 Cell line enhanced SH-SY5Y: 228.5;THP-1: 67.4 +NDST3 HSST3 ENSG00000164100 N-deacetylase and N-sulfotransferase 3 4 118033618-118258648 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056189 Uncertain Not detected Tissue enhanced cerebral cortex: 3.0;spleen: 2.8 cervix, uterine: 0.7 Cell line enriched 16 MOLT-4: 13.3 +HMGB2 HMG2 ENSG00000164104 High mobility group box 2 4 173331695-173335125 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003506, CAB037206, HPA053314 Enhanced Supported Nucleus
Nucleoli Renal cancer:7.60e-12 (unfavourable), Liver cancer:3.76e-5 (unfavourable), Melanoma:3.13e-4 (unfavourable), Pancreatic cancer:7.04e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 1464.0 Expressed in all +SAP30 ENSG00000164105 Sin3A associated protein 30 4 173369969-173377532 Predicted secreted proteins Evidence at protein level CAB022627, HPA059012 Enhanced Supported Nucleoplasm Renal cancer:1.54e-7 (unfavourable), Liver cancer:1.24e-6 (unfavourable) Expressed in all Expressed in all testis: 34.8 Expressed in all +SCRG1 SCRG-1 ENSG00000164106 Stimulator of chondrogenesis 1 4 173384701-173406380 Predicted secreted proteins Evidence at protein level HPA012882 Approved Tissue enriched Tissue enhanced cerebral cortex: 24.4;testis: 15.5 smooth muscle: 11.0 Group enriched 13 HSkMC: 4.3;WM-115: 17.6 +HAND2 bHLHa26, dHand, Hed, Thing2 ENSG00000164107 Heart and neural crest derivatives expressed 2 4 173524969-173530229 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019591, CAB025576 Approved Supported Nucleoplasm
Vesicles Tissue enhanced Tissue enhanced endometrium: 83.9 smooth muscle: 77.9 Cell line enriched 21 SH-SY5Y: 660.2 +MAD2L1 HSMAD2, MAD2 ENSG00000164109 MAD2 mitotic arrest deficient-like 1 (yeast) 4 120055608-120067074 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003348 Uncertain Approved Nucleoplasm Renal cancer:3.07e-11 (unfavourable), Liver cancer:5.15e-5 (unfavourable), Lung cancer:2.17e-4 (unfavourable) Expressed in all Mixed lymph node: 4.6 Mixed +ANXA5 ANX5, ENX2 ENSG00000164111 Annexin A5 4 121667955-121697113 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level CAB003677, HPA035330 Approved Approved Nuclear membrane Renal cancer:9.29e-7 (unfavourable), Liver cancer:1.64e-5 (unfavourable), Head and neck cancer:3.01e-5 (unfavourable), Urothelial cancer:1.26e-4 (unfavourable), Endometrial cancer:3.64e-4 (favourable), Stomach cancer:7.19e-4 (unfavourable) Expressed in all Expressed in all placenta: 616.2 Expressed in all +TMEM155 FLJ30834 ENSG00000164112 Transmembrane protein 155 4 121758933-121765427 Predicted secreted proteins Evidence at transcript level HPA077585 Approved Mixed Group enriched 6 cerebral cortex: 27.6;placenta: 5.7 lymph node: 3.0 Cell line enhanced fHDF/TERT166: 4.0;HAP1: 2.2;LHCN-M2: 5.5;MOLT-4: 5.1 +ADAD1 Tenr ENSG00000164113 Adenosine deaminase domain containing 1 4 122378966-122429802 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 2122 testis: 212.1 all non-specific tissues: 0.0 Not detected +MAP9 ASAP, FLJ21159 ENSG00000164114 Microtubule associated protein 9 4 155342658-155376970 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced parathyroid gland: 79.9 cerebral cortex: 27.1 Cell line enhanced SH-SY5Y: 44.7 +GUCY1A3 GC-SA3, GUC1A3 ENSG00000164116 Guanylate cyclase 1 soluble subunit alpha 4 155666711-155732349 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB010887, HPA056004, HPA058617 Uncertain Supported Nucleus Lung cancer:2.38e-4 (favourable), Testis cancer:3.59e-4 (unfavourable), Renal cancer:7.59e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 136.7 smooth muscle: 43.8 Cell line enhanced HAP1: 7.2;Karpas-707: 7.1;MOLT-4: 15.2;RPTEC TERT1: 9.3;RT4: 11.7;SH-SY5Y: 9.5 +FBXO8 FBS, FBX8 ENSG00000164117 F-box protein 8 4 174236658-174284264 Predicted intracellular proteins Evidence at transcript level HPA002885 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.29e-7 (favourable) Expressed in all Expressed in all placenta: 45.0 Expressed in all +CEP44 KIAA1712 ENSG00000164118 Centrosomal protein 44 4 174283677-174333380 Predicted intracellular proteins Evidence at protein level HPA041515, HPA041835 Approved Expressed in all Mixed testis: 23.6 Expressed in all +HPGD SDR36C1 ENSG00000164120 Hydroxyprostaglandin dehydrogenase 15-(NAD) 4 174490177-174523154 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004919, HPA005679 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:3.20e-4 (favourable) Tissue enhanced Tissue enhanced urinary bladder: 375.7 stomach: 181.5 Cell line enhanced A549: 128.2;HEL: 282.4;RT4: 385.2 +ASB5 ENSG00000164122 Ankyrin repeat and SOCS box containing 5 4 176213673-176277571 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA028870 Approved Plasma membrane Head and neck cancer:5.67e-4 (unfavourable) Tissue enhanced Tissue enhanced skeletal muscle: 75.7 prostate: 20.8 Cell line enriched 14 LHCN-M2: 986.5 +C4orf45 FLJ25371 ENSG00000164123 Chromosome 4 open reading frame 45 4 158893134-159038760 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 50 testis: 20.1 bone marrow: 0.4 Not detected +TMEM144 FLJ11155 ENSG00000164124 Transmembrane protein 144 4 158201604-158255411 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA063554 Approved Mitochondria Endometrial cancer:2.89e-4 (favourable), Pancreatic cancer:8.48e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 90.5 testis: 46.9 Cell line enhanced BEWO: 32.7 +FAM198B C4orf18, DKFZp434L142, ENED, FLJ38155 ENSG00000164125 Family with sequence similarity 198 member B 4 158124474-158173318 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007227 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus Expressed in all Expressed in all adrenal gland: 271.5 Cell line enhanced ASC TERT1: 100.6;HSkMC: 120.9;HUVEC TERT2: 160.0 +NPY1R NPYR ENSG00000164128 Neuropeptide Y receptor Y1 4 163323961-163344832 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029903 Approved Nucleus
Mitochondria
Cytosol Breast cancer:7.68e-5 (favourable) Tissue enriched Tissue enhanced spleen: 151.8 breast: 39.6 Cell line enriched 16 HEL: 105.6 +NPY5R NPYR5 ENSG00000164129 Neuropeptide Y receptor Y5 4 163343939-163351934 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced spleen: 12.3;testis: 9.7 adipose tissue: 7.7 Not detected +NAA15 FLJ13340, NARG1, NATH, TBDN100 ENSG00000164134 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 4 139301455-139420033 Predicted intracellular proteins Evidence at protein level HPA023589, HPA050661 Approved Enhanced Cytosol Liver cancer:2.03e-4 (unfavourable) Expressed in all Expressed in all testis: 24.1 Expressed in all +IL15 IL-15, MGC9721 ENSG00000164136 Interleukin 15 4 141636599-141733987 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB004457, HPA037738 Approved Supported Nucleoplasm
Nuclear speckles Mixed Mixed spleen: 18.8 Mixed +FAM160A1 FLJ43373 ENSG00000164142 Family with sequence similarity 160 member A1 4 151409216-151663632 Predicted intracellular proteins Evidence at protein level HPA046348 Enhanced Approved Cytosol Mixed Mixed parathyroid gland: 16.7 Cell line enhanced SiHa: 9.2 +ARFIP1 HSU52521 ENSG00000164144 ADP ribosylation factor interacting protein 1 4 152779937-152918463 Predicted intracellular proteins Evidence at protein level CAB005080, HPA037375, HPA063759 Enhanced Supported Nucleus
Golgi apparatus
Vesicles Renal cancer:2.83e-10 (favourable), Colorectal cancer:5.75e-5 (favourable) Expressed in all Expressed in all endometrium: 39.4 Expressed in all +ICE1 KIAA0947 ENSG00000164151 Interactor of little elongation complex ELL subunit 1 5 5420664-5490234 Predicted intracellular proteins Evidence at protein level HPA054452, HPA061934 Uncertain Supported Nucleoplasm
Nuclear bodies Liver cancer:1.66e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.2 Expressed in all +HHIP FLJ20992, HIP ENSG00000164161 Hedgehog interacting protein 4 144646021-144745271 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012616 Uncertain Approved Nucleoplasm Mixed Tissue enhanced lung: 24.2 cerebral cortex: 10.8 Group enriched 6 HUVEC TERT2: 269.0;RH-30: 62.9;TIME: 306.5 +ANAPC10 APC10, DKFZP564L0562, DOC1 ENSG00000164162 Anaphase promoting complex subunit 10 4 144967112-145098541 Predicted intracellular proteins Evidence at protein level HPA044547 Approved Approved Nucleoplasm
Golgi apparatus Melanoma:8.22e-4 (unfavourable) Expressed in all Expressed in all testis: 35.7 Expressed in all +ABCE1 OABP, RLI, RLI1, RNASEL1, RNASELI, RNS4I ENSG00000164163 ATP binding cassette subfamily E member 1 4 145097932-145129179 Predicted intracellular proteins Evidence at protein level CAB012476, HPA036846 Approved Enhanced Cytosol Pancreatic cancer:1.88e-4 (unfavourable), Liver cancer:6.29e-4 (unfavourable), Colorectal cancer:8.69e-4 (favourable) Expressed in all Expressed in all testis: 46.1 Expressed in all +OTUD4 DUBA6, HSHIN1, KIAA1046 ENSG00000164164 OTU deubiquitinase 4 4 145110838-145180161 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036623 Uncertain Approved Cytosol Expressed in all Expressed in all testis: 72.7 Expressed in all +LSM6 YDR378C ENSG00000164167 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated 4 146175685-146200000 Predicted intracellular proteins Evidence at protein level HPA045079 Approved Approved Actin filaments Melanoma:3.88e-4 (unfavourable), Renal cancer:6.65e-4 (unfavourable) Expressed in all Mixed lymph node: 11.1 Expressed in all +TMEM184C FLJ10846, TMEM34 ENSG00000164168 Transmembrane protein 184C 4 147617383-147672044 Predicted membrane proteins Evidence at protein level HPA054013 Uncertain Approved Nucleoplasm
Vesicles Renal cancer:2.31e-7 (favourable), Pancreatic cancer:6.37e-4 (unfavourable) Expressed in all Group enriched 6 parathyroid gland: 253.9;thyroid gland: 53.2 placenta: 27.6 Expressed in all +PRMT9 FLJ46629, PRMT10 ENSG00000164169 Protein arginine methyltransferase 9 4 147637785-147684230 Predicted intracellular proteins Evidence at protein level HPA036844, HPA042537 Uncertain Approved Nucleoplasm
Microtubules
Cytosol Renal cancer:3.58e-7 (favourable) Expressed in all Mixed parathyroid gland: 14.2 Expressed in all +ITGA2 CD49B ENSG00000164171 Integrin subunit alpha 2 5 52989326-53094779 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB017690, HPA060991, HPA063556 Enhanced Approved Nucleus
Cytosol Pancreatic cancer:1.02e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 24.5 Cell line enhanced BJ hTERT+: 74.4;HaCaT: 82.1 +MOCS2 MOCO1 ENSG00000164172 Molybdenum cofactor synthesis 2 5 53095679-53110063 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037679, HPA037680 Approved Approved Nucleus
Cytosol Renal cancer:3.68e-6 (favourable) Expressed in all Expressed in all kidney: 106.4 Expressed in all +SLC45A2 AIM-1, MATP, OCA4 ENSG00000164175 Solute carrier family 45 member 2 5 33944616-33984730 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Tissue enhanced skin: 1.2;testis: 1.2 prostate,rectum: 0.3 Cell line enriched 43 SK-MEL-30: 48.5 +EDIL3 DEL1 ENSG00000164176 EGF like repeats and discoidin domains 3 5 83940554-84384793 Predicted secreted proteins Evidence at protein level HPA020415 Approved Expressed in all Tissue enhanced cerebral cortex: 131.5 epididymis: 54.6 Cell line enhanced LHCN-M2: 141.8;TIME: 165.9;U-2 OS: 174.3;U-87 MG: 110.4 +TMEM161B MGC33214 ENSG00000164180 Transmembrane protein 161B 5 88189633-88269476 Predicted membrane proteins Evidence at protein level HPA044562 Uncertain Expressed in all Expressed in all parathyroid gland: 59.9 Expressed in all +ELOVL7 FLJ23563 ENSG00000164181 ELOVL fatty acid elongase 7 5 60751791-60844389 Enzymes, Predicted membrane proteins Evidence at protein level HPA036337 Approved Renal cancer:1.54e-9 (favourable), Endometrial cancer:3.87e-5 (unfavourable) Expressed in all Mixed prostate: 35.8 Cell line enhanced HEL: 33.1 +NDUFAF2 B17.2L, mimitin, MMTN, NDUFA12L ENSG00000164182 NADH:ubiquinone oxidoreductase complex assembly factor 2 5 60945129-61153037 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA048082, HPA054776 Supported Enhanced Mitochondria Renal cancer:2.49e-4 (unfavourable), Liver cancer:2.56e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 48.0 Expressed in all +ZNF474 4933409D10Rik, FLJ32921 ENSG00000164185 Zinc finger protein 474 5 122129513-122153571 Predicted intracellular proteins Evidence at transcript level Mixed Group enriched 8 fallopian tube: 26.7;testis: 13.4 lung: 2.5 Mixed +LMBRD2 DKFZp434H2226 ENSG00000164187 LMBR1 domain containing 2 5 36098412-36151961 Predicted membrane proteins Evidence at protein level HPA012165 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 25.4 Mixed +RANBP3L FLJ25422 ENSG00000164188 RAN binding protein 3 like 5 36248434-36302114 Predicted intracellular proteins Evidence at protein level HPA037471, HPA037472, HPA061526 Approved Uncertain Nucleoplasm Tissue enhanced Tissue enhanced cerebral cortex: 31.0;kidney: 28.7;prostate: 23.0 breast: 10.0 Cell line enhanced ASC diff: 8.5;HSkMC: 1.8;T-47d: 2.0 +NIPBL DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2 ENSG00000164190 NIPBL, cohesin loading factor 5 36876759-37066413 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040834, HPA058239 Approved Supported Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 43.0 Expressed in all +RNF180 ENSG00000164197 Ring finger protein 180 5 64165844-64372869 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006897 Approved Approved Cytosol Renal cancer:6.81e-5 (favourable) Tissue enhanced Tissue enhanced parathyroid gland: 62.4 thyroid gland: 24.8 Cell line enriched 5 RPMI-8226: 20.6 +ADGRV1 DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1 ENSG00000164199 Adhesion G protein-coupled receptor V1 5 90529344-91164437 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA067503 Approved Approved Lipid droplets Mixed Tissue enriched 11 adrenal gland: 261.4 kidney: 22.9 Cell line enhanced AF22: 15.3;HAP1: 23.8;NTERA-2: 11.7;SCLC-21H: 13.1 +SLC25A46 ENSG00000164209 Solute carrier family 25 member 46 5 110738136-110765161 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039601, HPA071582 Approved Supported Mitochondria Thyroid cancer:2.52e-4 (unfavourable), Colorectal cancer:8.41e-4 (favourable) Expressed in all Expressed in all testis: 37.6 Expressed in all +STARD4 ENSG00000164211 StAR related lipid transfer domain containing 4 5 111496033-111512590 Predicted intracellular proteins Evidence at protein level HPA046177, HPA048081 Approved Approved Plasma membrane Liver cancer:4.80e-5 (unfavourable), Renal cancer:5.89e-5 (unfavourable), Urothelial cancer:2.84e-4 (unfavourable) Expressed in all Mixed duodenum: 41.4 Mixed +PGGT1B BGGI, GGTI ENSG00000164219 Protein geranylgeranyltransferase type I subunit beta 5 115204012-115262872 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030646 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all parathyroid gland: 19.0 Expressed in all +F2RL2 PAR3 ENSG00000164220 Coagulation factor II thrombin receptor like 2 5 76615482-76623434 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Colorectal cancer:4.69e-4 (favourable) Mixed Tissue enhanced gallbladder: 10.9 smooth muscle: 5.6 Cell line enhanced BJ hTERT+: 43.2;HEL: 65.9;hTEC/SVTERT24-B: 34.7;U-138 MG: 52.8;WM-115: 67.6 +CCDC112 MGC39633 ENSG00000164221 Coiled-coil domain containing 112 5 115267188-115296831 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045120, HPA050621 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.51e-6 (unfavourable) Expressed in all Tissue enriched 6 testis: 73.7 cerebral cortex: 13.1 Expressed in all +ANKRD33B ENSG00000164236 Ankyrin repeat domain 33B 5 10564330-10657816 Predicted intracellular proteins Evidence at protein level HPA056974 Uncertain Approved Mitochondria Renal cancer:4.16e-5 (favourable) Tissue enhanced Mixed cerebral cortex: 12.9 Cell line enhanced HDLM-2: 44.9;HMC-1: 27.3 +CMBL FLJ23617 ENSG00000164237 Carboxymethylenebutenolidase homolog 5 10275875-10308026 Predicted intracellular proteins Evidence at protein level HPA036571 Uncertain Ovarian cancer:1.99e-4 (favourable) Expressed in all Tissue enhanced kidney: 315.7 duodenum: 177.0 Mixed +C5orf63 FLJ44606, YDR286C ENSG00000164241 Chromosome 5 open reading frame 63 5 127042558-127073492 Predicted intracellular proteins Evidence at transcript level HPA043240 Approved Approved Mitochondria Mixed Mixed cerebral cortex: 36.8 Cell line enhanced U-87 MG: 49.1 +PRRC1 FLJ32875 ENSG00000164244 Proline rich coiled-coil 1 5 127517609-127555089 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039212 Supported Approved Vesicles Breast cancer:9.35e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 54.1 Expressed in all +F2RL1 GPR11, PAR2 ENSG00000164251 F2R like trypsin receptor 1 5 76818933-76835315 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level CAB012989, HPA014091 Approved Approved Plasma membrane Renal cancer:5.86e-7 (favourable), Colorectal cancer:3.88e-4 (favourable), Head and neck cancer:5.88e-4 (unfavourable), Lung cancer:8.92e-4 (unfavourable) Expressed in all Mixed colon: 58.9 Cell line enhanced PC-3: 113.9;RPTEC TERT1: 152.3 +AGGF1 FLJ10283, GPATC7, GPATCH7, HSU84971, VG5Q ENSG00000164252 Angiogenic factor with G-patch and FHA domains 1 5 77029251-77065234 Disease related genes, Predicted intracellular proteins Evidence at protein level Colorectal cancer:2.87e-4 (favourable) Expressed in all Expressed in all testis: 33.8 Mixed +WDR41 FLJ10904 ENSG00000164253 WD repeat domain 41 5 77425970-77620611 Predicted intracellular proteins Evidence at protein level HPA043124 Approved Approved Nucleus
Golgi apparatus
Cytosol Liver cancer:4.47e-4 (unfavourable) Expressed in all Expressed in all testis: 50.6 Expressed in all +PRDM9 KMT8B, MSBP3, PFM6, ZNF899 ENSG00000164256 PR/SET domain 9 5 23443586-23528597 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059555 Uncertain Not detected Group enriched 7 epididymis: 1.7;testis: 7.1 bone marrow: 0.6 Cell line enriched 7 U-266/70: 5.0 +NDUFS4 AQDQ, CI-18 ENSG00000164258 NADH:ubiquinone oxidoreductase subunit S4 5 53560633-53683340 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003884 Supported Supported Mitochondria Renal cancer:3.85e-6 (favourable) Expressed in all Expressed in all kidney: 139.9 Expressed in all +SCGB3A2 LU103, PNSP1, UGRP1 ENSG00000164265 Secretoglobin family 3A member 2 5 147870682-147882191 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 188 lung: 1867.1 thyroid gland: 9.9 Cell line enhanced A-431: 76.2;EFO-21: 49.6;NTERA-2: 60.1;PC-3: 279.6 +SPINK1 PCTT, PSTI, Spink3, TATI ENSG00000164266 Serine peptidase inhibitor, Kazal type 1 5 147824568-147831786 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB026366, HPA027498 Enhanced Renal cancer:5.44e-7 (unfavourable), Urothelial cancer:2.15e-5 (favourable) Tissue enhanced Tissue enriched 8 pancreas: 7127.3 stomach: 927.5 Group enriched 9 CACO-2: 208.3;RT4: 548.2 +HTR4 5-HT4 ENSG00000164270 5-hydroxytryptamine receptor 4 5 148451032-148677235 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040591 Approved Not detected Tissue enhanced duodenum: 4.8;small intestine: 10.0 rectum: 3.1 Not detected +ESM1 ENSG00000164283 Endothelial cell specific molecule 1 5 54977864-55022671 Predicted secreted proteins Evidence at protein level Cervical cancer:2.11e-7 (unfavourable), Renal cancer:4.00e-4 (unfavourable) Tissue enriched Tissue enhanced kidney: 19.2;thyroid gland: 27.2 endometrium: 5.8 Group enriched 5 HUVEC TERT2: 236.2;TIME: 434.9 +GRPEL2 DKFZp451C205, FLJ23713, Mt-GrpE#2 ENSG00000164284 GrpE like 2, mitochondrial 5 149345430-149354583 Predicted intracellular proteins Evidence at protein level HPA018173, HPA023211 Uncertain Enhanced Mitochondria Liver cancer:6.16e-8 (unfavourable), Colorectal cancer:3.87e-5 (favourable), Endometrial cancer:2.21e-4 (unfavourable), Renal cancer:4.20e-4 (unfavourable) Expressed in all Tissue enhanced esophagus: 30.4 thyroid gland: 9.7 Expressed in all +CDC20B FLJ37927 ENSG00000164287 Cell division cycle 20B 5 55112995-55173175 Predicted intracellular proteins Evidence at protein level HPA053900 Uncertain Tissue enhanced Group enriched 6 endometrium: 1.2;fallopian tube: 3.4;kidney: 1.2;testis: 4.9 lung: 0.4 Not detected +ARSK DKFZp313G1735, TSULF ENSG00000164291 Arylsulfatase family member K 5 95555074-95605064 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA042384 Approved Approved Nucleus
Vesicles Liver cancer:2.59e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 22.7 thyroid gland: 8.5 Expressed in all +RHOBTB3 KIAA0878 ENSG00000164292 Rho related BTB domain containing 3 5 95713522-95824383 Predicted intracellular proteins Evidence at protein level HPA000265 Uncertain Vesicles Expressed in all Expressed in all ovary: 99.0 Cell line enhanced HaCaT: 281.3 +GPX8 EPLA847, UNQ847 ENSG00000164294 Glutathione peroxidase 8 (putative) 5 55160118-55167071 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036720 Enhanced Supported Actin filaments
Cytosol Renal cancer:5.13e-9 (unfavourable), Stomach cancer:7.96e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 48.0 Mixed +TIGD6 DKFZp761E2110 ENSG00000164296 Tigger transposable element derived 6 5 149993118-150001167 Predicted intracellular proteins Evidence at protein level HPA044599 Uncertain Approved Nucleoplasm
Vesicles
Actin filaments Colorectal cancer:5.35e-4 (favourable), Pancreatic cancer:5.88e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 21.4 testis: 6.7 Mixed +SPZ1 FLJ25709, NYD-TSP1, PPP1R148 ENSG00000164299 Spermatogenic leucine zipper 1 5 80319625-80321842 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enriched 453 testis: 45.2 all non-specific tissues: 0.0 Not detected +SERINC5 C5orf12, TPO1 ENSG00000164300 Serine incorporator 5 5 80111651-80256079 Predicted membrane proteins Evidence at protein level HPA037898, HPA037899 Supported Uncertain Nucleus
Golgi apparatus
Vesicles Expressed in all Mixed testis: 55.4 Mixed +ENPP6 MGC33971 ENSG00000164303 Ectonucleotide pyrophosphatase/phosphodiesterase 6 4 184088706-184221230 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042740 Approved Approved Golgi apparatus Tissue enriched Tissue enhanced kidney: 30.6;ovary: 15.0 cerebral cortex: 8.6 Cell line enhanced Karpas-707: 2.3;SH-SY5Y: 3.8;U-266/70: 2.2;U-266/84: 1.1 +CAGE1 bA69L16.7, CT95, CTAG3 ENSG00000164304 Cancer antigen 1 6 7326656-7389743 Predicted intracellular proteins Evidence at protein level HPA029832 Uncertain Not detected Tissue enriched 77 testis: 8.3 endometrium: 0.1 Not detected +CASP3 apopain, CPP32, CPP32B, Yama ENSG00000164305 Caspase 3 4 184627696-184649509 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000091, HPA002643, CAB008381 Enhanced Supported Nucleoplasm
Mitochondria Renal cancer:2.30e-5 (unfavourable), Endometrial cancer:2.24e-4 (favourable) Expressed in all Expressed in all duodenum: 54.4 Expressed in all +PRIMPOL CCDC111, FLJ33167 ENSG00000164306 Primase and DNA directed polymerase 4 184649613-184694963 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA054372 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Mixed endometrium: 17.2 Expressed in all +ERAP1 A-LAP, ARTS-1, ERAAP1, KIAA0525, PILS-AP ENSG00000164307 Endoplasmic reticulum aminopeptidase 1 5 96760810-96808100 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025095, HPA042317 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all placenta: 68.0 Expressed in all +ERAP2 L-RAP, LRAP ENSG00000164308 Endoplasmic reticulum aminopeptidase 2 5 96875939-96919716 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025618, HPA034498, HPA064360 Enhanced Approved Golgi apparatus Pancreatic cancer:1.20e-4 (unfavourable) Expressed in all Mixed lymph node: 49.3 Cell line enhanced CAPAN-2: 155.3;hTEC/SVTERT24-B: 83.9;TIME: 152.1 +CMYA5 C5orf10, DKFZp451G223, myospryn, SPRYD2, TRIM76 ENSG00000164309 Cardiomyopathy associated 5 5 79689877-79800240 Predicted intracellular proteins Evidence at protein level Mixed Group enriched 8 heart muscle: 102.2;skeletal muscle: 172.4 ovary: 18.2 Cell line enhanced RT4: 1.2;THP-1: 3.6 +EGFLAM AGRINL, AGRNL, FLJ39155, PIKA ENSG00000164318 EGF like, fibronectin type III and laminin G domains 5 38258409-38465021 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:4.47e-5 (unfavourable) Expressed in all Tissue enhanced placenta: 73.4 adipose tissue: 43.0 Cell line enhanced hTERT-HME1: 12.6;HUVEC TERT2: 13.4;LHCN-M2: 30.8;U-2 OS: 16.5 +CFAP97 DKFZp434F1728, hmw, KIAA1430 ENSG00000164323 Cilia and flagella associated protein 97 4 185159665-185209504 Predicted intracellular proteins Evidence at protein level HPA049446, HPA053335 Approved Supported Nucleoli
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 67.7 Expressed in all +TMEM174 FLJ31268, MGC13034 ENSG00000164325 Transmembrane protein 174 5 73173195-73175143 Predicted membrane proteins Evidence at protein level HPA037975 Enhanced Renal cancer:3.30e-6 (favourable) Tissue enriched Tissue enriched 685 kidney: 159.4 thyroid gland: 0.2 Not detected +CARTPT CART ENSG00000164326 CART prepropeptide 5 71719163-71721048 FDA approved drug targets, Predicted secreted proteins Evidence at protein level CAB025515, HPA046278 Enhanced Stomach cancer:4.36e-4 (unfavourable) Tissue enriched Tissue enriched 8 adrenal gland: 132.5 cerebral cortex: 17.4 Not detected +RICTOR AVO3, KIAA1999, MGC39830, PIA ENSG00000164327 RPTOR independent companion of MTOR complex 2 5 38937919-39074408 Predicted intracellular proteins Evidence at protein level HPA037802, HPA037803 Approved Approved Mitochondria Expressed in all Expressed in all testis: 17.2 Expressed in all +PAPD4 FLJ38499, GLD2, TUT2 ENSG00000164329 Poly(A) RNA polymerase D4, non-canonical 5 79612120-79686648 Enzymes, Predicted intracellular proteins Evidence at protein level HPA054468 Approved Cytosol Expressed in all Expressed in all spleen: 38.4 Expressed in all +EBF1 EBF, OLF1 ENSG00000164330 Early B-cell factor 1 5 158695916-159099761 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA061169 Approved Nucleoplasm
Vesicles Renal cancer:9.62e-7 (unfavourable), Stomach cancer:7.80e-4 (unfavourable) Mixed Tissue enhanced adipose tissue: 41.6 placenta: 16.2 Cell line enhanced ASC diff: 27.3;HSkMC: 22.6;REH: 81.2 +ANKRA2 ENSG00000164331 Ankyrin repeat family A member 2 5 73552335-73565686 Predicted intracellular proteins Evidence at protein level HPA065263 Approved Plasma membrane
Cell Junctions Expressed in all Expressed in all thyroid gland: 26.2 Expressed in all +UBLCP1 CPUB1, MGC10067 ENSG00000164332 Ubiquitin like domain containing CTD phosphatase 1 5 159263081-159286040 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039615 Approved Enhanced Nucleus
Nucleoli Liver cancer:4.46e-5 (unfavourable) Expressed in all Expressed in all testis: 49.9 Expressed in all +FAM170A ZNFD ENSG00000164334 Family with sequence similarity 170 member A 5 119629559-119635822 Predicted intracellular proteins Evidence at protein level HPA037900, HPA037902 Enhanced Not detected Tissue enriched 104 testis: 21.0 skin: 0.2 Not detected +UTP15 FLJ12787, FLJ23637, NET21 ENSG00000164338 UTP15, small subunit processome component 5 73565443-73583377 Predicted intracellular proteins Evidence at protein level HPA044697 Supported Nucleoli
Endoplasmic reticulum Expressed in all Expressed in all bone marrow: 23.2 Expressed in all +TLR3 CD283 ENSG00000164342 Toll like receptor 3 4 186069152-186088069 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025658 Enhanced Pancreatic cancer:3.09e-4 (unfavourable) Mixed Mixed placenta: 24.5 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 29.4;CAPAN-2: 42.4 +KLKB1 KLK3 ENSG00000164344 Kallikrein B1 4 186208979-186258471 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 45 liver: 155.0 gallbladder,kidney: 3.4 Cell line enhanced NTERA-2: 2.9;SCLC-21H: 2.3 +NSA2 FLJ94393, HCLG1, HUSSY-29, TINP1 ENSG00000164346 NSA2, ribosome biogenesis homolog 5 74766991-74780113 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043487 Approved Supported Nucleus
Nucleoli Expressed in all Expressed in all ovary: 73.8 Expressed in all +GFM2 EFG2, FLJ21661 ENSG00000164347 G elongation factor mitochondrial 2 5 74721204-74767371 Predicted intracellular proteins Evidence at protein level HPA036863 Uncertain Renal cancer:1.33e-5 (favourable) Expressed in all Expressed in all fallopian tube: 36.6 Expressed in all +TERT EST2, hEST2, TCS1, TP2, TRT ENSG00000164362 Telomerase reverse transcriptase 5 1253147-1295069 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA054641, HPA065897 Supported Enhanced Nucleoplasm
Nuclear speckles
Cytosol Mixed Not detected lymph node,testis: 0.5 Cell line enhanced ASC TERT1: 349.5;fHDF/TERT166: 388.9;HBEC3-KT: 725.5;hTEC/SVTERT24-B: 626.8;TIME: 672.9 +SLC6A18 FLJ31236, Xtrp2 ENSG00000164363 Solute carrier family 6 member 18 5 1225355-1246189 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA011885 Enhanced Tissue enriched Tissue enriched 83 kidney: 8.2 all non-specific tissues: 0.0 Not detected +CCDC127 FLJ25701 ENSG00000164366 Coiled-coil domain containing 127 5 196871-218215 Predicted intracellular proteins Evidence at protein level HPA045052 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:4.04e-6 (unfavourable), Renal cancer:5.95e-5 (unfavourable), Breast cancer:7.01e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 23.0 Expressed in all +FOXQ1 HFH1 ENSG00000164379 Forkhead box Q1 6 1312440-1314748 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059700 Supported Nucleus Prostate cancer:6.68e-4 (favourable) Expressed in all Tissue enhanced stomach: 105.8;urinary bladder: 43.8 skin: 33.1 Cell line enhanced CACO-2: 32.2;HaCaT: 39.8;Hep G2: 65.9;RT4: 32.0 +ADGRF2 GPR111, hGPCR35, PGR20 ENSG00000164393 Adhesion G protein-coupled receptor F2 6 47656436-47697797 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA035507 Uncertain Not detected Tissue enhanced fallopian tube: 1.5;skin: 1.4 esophagus: 0.3 Not detected +ACSL6 ACS2, FACL6, KIAA0837, LACS2, LACS5 ENSG00000164398 Acyl-CoA synthetase long-chain family member 6 5 131949973-132012243 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040470 Enhanced Group enriched Group enriched 6 bone marrow: 18.0;cerebral cortex: 61.9;parathyroid gland: 22.5;seminal vesicle: 29.0;testis: 51.4 adrenal gland: 6.4 Group enriched 6 SCLC-21H: 13.0;U-937: 5.2 +IL3 IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF ENSG00000164399 Interleukin 3 5 132060529-132063204 Predicted secreted proteins Evidence at protein level Not detected Not detected bone marrow,epididymis,parathyroid gland,testis: 0.1 Cell line enriched 15 HMC-1: 2.2 +CSF2 GM-CSF, GMCSF ENSG00000164400 Colony stimulating factor 2 5 132073790-132076170 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA057404, HPA062006 Enhanced Vesicles Mixed Tissue enhanced lung: 3.0 urinary bladder: 0.9 Cell line enhanced BJ hTERT+: 74.1;hTEC/SVTERT24-B: 20.9 +SEPT8 KIAA0202, SEP2 ENSG00000164402 Septin 8 5 132750817-132807241 Predicted intracellular proteins Evidence at protein level HPA005665, HPA036534 Approved Approved Actin filaments
Cytosol Renal cancer:6.98e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 280.3 Mixed +SHROOM1 APXL2, KIAA1960 ENSG00000164403 Shroom family member 1 5 132822141-132830898 Predicted intracellular proteins Evidence at protein level HPA037690, HPA037691 Uncertain Approved Vesicles Renal cancer:5.72e-6 (unfavourable) Expressed in all Tissue enhanced prostate: 54.5 seminal vesicle: 21.3 Mixed +GDF9 ENSG00000164404 Growth differentiation factor 9 5 132861181-132866884 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA069146 Supported Tissue enriched Group enriched 5 epididymis: 5.0;testis: 14.1 thyroid gland: 1.8 Mixed +UQCRQ QCR8, QP-C, UQCR7 ENSG00000164405 Ubiquinol-cytochrome c reductase complex III subunit VII 5 132866560-132868031 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046693, HPA053323 Approved Enhanced Mitochondria Endometrial cancer:4.23e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 376.0 Expressed in all +LEAP2 LEAP-2 ENSG00000164406 Liver enriched antimicrobial peptide 2 5 132872322-132875046 Plasma proteins, Predicted secreted proteins Evidence at protein level Urothelial cancer:2.68e-4 (favourable) Tissue enriched Tissue enriched 9 liver: 66.1 small intestine: 7.7 Mixed +GJB7 bA136M9.1, CX25 ENSG00000164411 Gap junction protein beta 7 6 87282978-87329278 Predicted membrane proteins Evidence at transcript level Mixed Group enriched 7 fallopian tube: 11.1;placenta: 3.8 lung: 1.0 Cell line enhanced BEWO: 4.3;HDLM-2: 7.0;MCF7: 3.1;RT4: 2.9 +SLC35A1 CMPST, hCST ENSG00000164414 Solute carrier family 35 member A1 6 87470623-87512336 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:2.70e-6 (unfavourable) Expressed in all Expressed in all prostate: 59.5 Expressed in all +GRIK2 GluK2, GLUR6, MRT6 ENSG00000164418 Glutamate ionotropic receptor kainate type subunit 2 6 101398788-102070083 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014395, HPA014623, CAB022463 Approved Tissue enhanced Tissue enhanced cerebral cortex: 22.5 thyroid gland: 6.3 Cell line enhanced BJ: 14.3;BJ hTERT+: 22.6;fHDF/TERT166: 16.5;WM-115: 25.2 +MB21D1 C6orf150, cGAS ENSG00000164430 Mab-21 domain containing 1 6 73413515-73452276 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031700, HPA031702 Enhanced Approved Microtubule organizing center
Cytosol Renal cancer:2.27e-7 (unfavourable) Expressed in all Mixed bone marrow: 8.7 Cell line enhanced RH-30: 40.2 +FABP7 B-FABP, BLBP ENSG00000164434 Fatty acid binding protein 7 6 122779475-122784074 Predicted intracellular proteins Evidence at protein level CAB025488, HPA028825, CAB058697 Enhanced Renal cancer:1.65e-6 (unfavourable), Breast cancer:2.49e-4 (favourable) Group enriched Group enriched 13 breast: 33.1;cerebral cortex: 102.3 skin: 5.2 Group enriched 8 AF22: 75.1;U-251 MG: 17.6;WM-115: 45.7 +TLX3 HOX11L2, RNX ENSG00000164438 T-cell leukemia homeobox 3 5 171309284-171312134 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030504, HPA060957, HPA069359 Approved Supported Nucleoplasm Tissue enhanced Not detected all non-specific tissues: 0.0 Cell line enriched 6 SH-SY5Y: 28.2 +TXLNB C6orf198, dJ522B19.2, DKFZp451A175, MDP77 ENSG00000164440 Taxilin beta 6 139240061-139292139 Predicted intracellular proteins Evidence at protein level HPA030401, HPA030402, HPA030403 Enhanced Mixed Group enriched 6 heart muscle: 52.2;skeletal muscle: 102.3 ovary: 13.7 Cell line enhanced Daudi: 3.4;RPMI-8226: 2.5;U-698: 4.7 +CITED2 MRG1 ENSG00000164442 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 6 139371807-139374620 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016157, CAB069879 Supported Supported Nucleoplasm Stomach cancer:3.33e-4 (unfavourable), Renal cancer:3.40e-4 (favourable) Expressed in all Expressed in all thyroid gland: 379.3 Cell line enhanced fHDF/TERT166: 828.8 +FAM26D C6orf78, FLJ32239 ENSG00000164451 Family with sequence similarity 26 member D 6 116529013-116558868 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Not detected Tissue enriched 46 placenta: 33.8 testis: 0.7 Not detected +T ENSG00000164458 T brachyury transcription factor 6 166157656-166168700 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003322 Uncertain Supported Nucleus Tissue enriched Tissue enriched 20 parathyroid gland: 8.7 testis: 0.4 Group enriched 6 HeLa: 10.3;SCLC-21H: 4.2 +CREBRF C5orf41, LRF ENSG00000164463 CREB3 regulatory factor 5 173056352-173139284 Predicted intracellular proteins Evidence at protein level HPA015329 Supported Nucleus Renal cancer:3.20e-7 (favourable), Urothelial cancer:9.30e-4 (favourable) Expressed in all Expressed in all bone marrow: 43.6 Mixed +DCBLD1 dJ94G16.1, MGC46341 ENSG00000164465 Discoidin, CUB and LCCL domain containing 1 6 117453817-117569858 Predicted membrane proteins Evidence at protein level HPA059667 Approved Renal cancer:8.57e-8 (unfavourable), Cervical cancer:6.44e-5 (unfavourable) Expressed in all Mixed gallbladder: 14.3 Mixed +SFXN1 FLJ12876 ENSG00000164466 Sideroflexin 1 5 175477062-175529742 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019543, HPA063745 Uncertain Enhanced Mitochondria Expressed in all Expressed in all liver: 51.7 Expressed in all +SAMD3 bA73O6.2, FLJ34032 ENSG00000164483 Sterile alpha motif domain containing 3 6 130144315-130365425 Predicted intracellular proteins Evidence at protein level HPA028992, HPA028993 Uncertain Not detected Tissue enhanced spleen: 13.0 lymph node: 11.5 Group enriched 5 HBF TERT88: 1.7;HDLM-2: 3.1;hTEC/SVTERT24-B: 2.2;NTERA-2: 1.7;PC-3: 1.1 +TMEM200A KIAA1913, TTMC ENSG00000164484 Transmembrane protein 200A 6 130365734-130443063 Predicted membrane proteins Evidence at protein level HPA014396 Uncertain Renal cancer:3.92e-4 (favourable) Mixed Tissue enhanced endometrium: 65.1 smooth muscle: 29.4 Cell line enhanced HBF TERT88: 39.5;hTEC/SVTERT24-B: 66.8 +IL22RA2 CRF2-S1, IL-22BP ENSG00000164485 Interleukin 22 receptor subunit alpha 2 6 137143820-137173648 Predicted secreted proteins Evidence at protein level HPA030582, CAB034906 Uncertain Mixed Tissue enhanced breast: 4.1;tonsil: 2.9 appendix: 1.9 Cell line enhanced U-937: 1.0 +DACT2 bA503C24.7, C6orf116, DAPPER2 ENSG00000164488 Dishevelled binding antagonist of beta catenin 2 6 168292830-168319754 Predicted intracellular proteins Evidence at transcript level HPA030251, HPA030252 Approved Endometrial cancer:1.07e-5 (favourable), Renal cancer:5.76e-5 (favourable) Tissue enhanced Tissue enhanced placenta: 18.8 prostate: 7.3 Group enriched 6 A549: 3.0;CACO-2: 2.2;EFO-21: 1.4;Hep G2: 1.0;hTCEpi: 1.3;NTERA-2: 2.3;SCLC-21H: 3.0 +PDSS2 bA59I9.3, C6orf210 ENSG00000164494 Decaprenyl diphosphate synthase subunit 2 6 107152557-107459564 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029685, HPA029686 Approved Enhanced Cytosol Renal cancer:3.75e-7 (favourable), Breast cancer:1.34e-5 (unfavourable), Colorectal cancer:5.74e-5 (favourable) Expressed in all Expressed in all prostate: 23.4 Expressed in all +C7orf72 ENSG00000164500 Chromosome 7 open reading frame 72 7 50096036-50159830 Predicted intracellular proteins Evidence at transcript level HPA026094 Uncertain Not detected Tissue enriched 31 testis: 5.9 lymph node,tonsil: 0.1 Cell line enriched 9 U-698: 7.2 +STXBP5 LLGL3, tomosyn ENSG00000164506 Syntaxin binding protein 5 6 147204425-147390476 Predicted intracellular proteins Evidence at protein level HPA039991, HPA049727, CAB079016 Enhanced Supported Enhanced Cytosol Renal cancer:2.74e-7 (unfavourable), Breast cancer:4.48e-4 (unfavourable) Expressed in all Tissue enriched 7 parathyroid gland: 278.8 testis: 40.2 Cell line enhanced HEL: 188.3;HMC-1: 193.3 +HIST1H2AA bA317E16.2, H2AFR ENSG00000164508 Histone cluster 1 H2A family member a 6 25726132-25726527 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041189 Supported Not detected Tissue enriched 90 testis: 17.1 kidney,pancreas: 0.1 Not detected +IL31RA CRL, CRL3, GLM-R, Glmr, IL-31RA ENSG00000164509 Interleukin 31 receptor A 5 55851379-55922853 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA051532, HPA068114 Approved Approved Nucleoplasm
Vesicles Mixed Tissue enhanced testis: 3.6 bone marrow: 1.2 Cell line enhanced hTERT-HME1: 10.7;U-2 OS: 21.6;U-87 MG: 23.4 +ANKRD55 FLJ11795 ENSG00000164512 Ankyrin repeat domain 55 5 56099678-56233359 Predicted intracellular proteins Evidence at protein level HPA051049 Approved Tissue enriched Group enriched 6 lymph node: 4.1;testis: 17.3 tonsil: 1.8 Group enriched 6 HEL: 30.8;HMC-1: 15.0;NB-4: 14.3 +RAET1E bA350J20.7, LETAL, ULBP4 ENSG00000164520 Retinoic acid early transcript 1E 6 149883375-149898102 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054022 Approved Focal adhesion sites
Cytosol Tissue enhanced Tissue enhanced esophagus: 70.8;skin: 29.0 tonsil: 10.3 Cell line enhanced HBEC3-KT: 15.9;HeLa: 20.3;hTCEpi: 15.6;SiHa: 11.2;U-87 MG: 9.0 +PI16 CD364, dJ90K10.5, MGC45378, MSMBBP ENSG00000164530 Peptidase inhibitor 16 6 36948263-36964837 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA076574 Approved Tissue enhanced Tissue enhanced cervix, uterine: 199.5 urinary bladder: 78.6 Cell line enhanced Daudi: 3.7;fHDF/TERT166: 3.6;U-2197: 1.0 +TBX20 ENSG00000164532 T-box 20 7 35202430-35254147 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Tissue enhanced adrenal gland: 5.6;heart muscle: 22.2 placenta: 5.0 Cell line enhanced SH-SY5Y: 7.5;WM-115: 4.2 +DAGLB DAGLBETA, KCCR13L ENSG00000164535 Diacylglycerol lipase beta 7 6409126-6484190 Predicted membrane proteins Evidence at protein level HPA069377 Supported Plasma membrane Ovarian cancer:7.18e-5 (unfavourable), Renal cancer:1.54e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 20.6 Expressed in all +KIAA0895 ENSG00000164542 KIAA0895 7 36324221-36390125 Predicted intracellular proteins Evidence at transcript level HPA021036, HPA061066 Uncertain Approved Nucleus
Plasma membrane
Cell Junctions
Cytosol Expressed in all Tissue enhanced testis: 44.5 parathyroid gland: 23.9 Cell line enhanced SCLC-21H: 51.4 +STK17A DRAK1 ENSG00000164543 Serine/threonine kinase 17a 7 43582758-43626786 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA018138, HPA037979 Uncertain Approved Nuclear speckles
Plasma membrane Expressed in all Expressed in all lymph node: 49.2 Expressed in all +TRA2A AWMS1, htra-2-alpha, tra2a ENSG00000164548 Transformer 2 alpha homolog 7 23504780-23532041 Predicted intracellular proteins Evidence at protein level HPA054018 Uncertain Supported Nucleoli
Vesicles Renal cancer:1.79e-6 (unfavourable), Liver cancer:2.07e-5 (unfavourable) Expressed in all Expressed in all endometrium: 67.7 Expressed in all +GALNT10 GalNAc-T10 ENSG00000164574 Polypeptide N-acetylgalactosaminyltransferase 10 5 154190730-154420984 Enzymes, Predicted secreted proteins Evidence at protein level HPA007525 Approved Approved Nucleoplasm
Golgi apparatus
Plasma membrane Endometrial cancer:3.33e-6 (favourable), Ovarian cancer:5.69e-4 (unfavourable) Expressed in all Expressed in all ovary: 81.7 Mixed +SAP30L FLJ11526, NS4ATP2 ENSG00000164576 SAP30 like 5 154445957-154461054 Predicted intracellular proteins Evidence at protein level HPA048665 Supported Nucleus
Nucleoli Pancreatic cancer:2.06e-5 (favourable), Renal cancer:1.71e-4 (favourable), Urothelial cancer:2.69e-4 (favourable), Head and neck cancer:9.09e-4 (favourable) Expressed in all Mixed parathyroid gland: 25.2 Expressed in all +RPS14 EMTB, S14 ENSG00000164587 Ribosomal protein S14 5 150443190-150449756 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA018504 Uncertain Enhanced Endoplasmic reticulum
Cytosol Liver cancer:7.73e-4 (unfavourable), Renal cancer:8.69e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 1992.0 Expressed in all +HCN1 BCNG-1, BCNG1, HAC-2 ENSG00000164588 Hyperpolarization activated cyclic nucleotide gated potassium channel 1 5 45254950-45696498 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA019195 Enhanced Not detected Tissue enriched 8 cerebral cortex: 4.9 heart muscle: 0.6 Cell line enhanced WM-115: 1.0 +MYOZ3 CS-3, CS3, FRP3 ENSG00000164591 Myozenin 3 5 150660874-150679365 Predicted intracellular proteins Evidence at protein level HPA039166 Enhanced Mixed Tissue enriched 11 skeletal muscle: 87.7 testis: 7.8 Cell line enhanced HAP1: 5.3;NTERA-2: 9.1;REH: 13.2 +COG5 GOLTC1, GTC90 ENSG00000164597 Component of oligomeric golgi complex 5 7 107201555-107564514 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020300, HPA041583 Uncertain Enhanced Nucleoplasm
Golgi apparatus Thyroid cancer:1.48e-4 (unfavourable), Liver cancer:3.77e-4 (unfavourable), Endometrial cancer:9.72e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 36.8 Mixed +NEUROD6 Atoh2, bHLHa2, Math-2, Nex1, NEX1M ENSG00000164600 Neuronal differentiation 6 7 31337461-31340894 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027046, HPA074530 Enhanced Approved Not detected Tissue enriched 180 cerebral cortex: 18.0 all non-specific tissues: 0.0 Cell line enriched 71 SCLC-21H: 7.0 +BMT2 C7orf60, DKFZp762M126, FLJ31818 ENSG00000164603 Base methyltransferase of 25S rRNA 2 homolog 7 112819147-112939916 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044405, HPA050733 Uncertain Approved Cytosol Expressed in all Mixed testis: 14.9 Expressed in all +GPR85 SREB2 ENSG00000164604 G protein-coupled receptor 85 7 113078331-113087778 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 16.7 skeletal muscle: 11.4 Cell line enriched 6 HEL: 99.3 +SLU7 9G8 ENSG00000164609 SLU7 homolog, splicing factor 5 160401641-160421711 Predicted intracellular proteins Evidence at protein level HPA035907, HPA058120 Uncertain Enhanced Nucleoplasm
Nuclear speckles Renal cancer:1.98e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 50.1 Expressed in all +RP9 PAP-1 ENSG00000164610 Retinitis pigmentosa 9 (autosomal dominant) 7 33094797-33109401 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031523, HPA050778 Uncertain Supported Nucleus
Cytosol Renal cancer:2.65e-5 (unfavourable), Liver cancer:2.58e-4 (unfavourable) Expressed in all Expressed in all testis: 25.9 Expressed in all +PTTG1 EAP1, HPTTG, PTTG, securin, TUTR1 ENSG00000164611 Pituitary tumor-transforming 1 5 160421822-160428744 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB008373, HPA008890, HPA045034 Enhanced Supported Nucleoli
Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.62e-6 (unfavourable) Expressed in all Tissue enhanced testis: 286.7 thyroid gland: 121.5 Expressed in all +CAMLG CAML, GET2 ENSG00000164615 Calcium modulating ligand 5 134738501-134752160 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA052636, HPA056472 Approved Approved Nucleus
Nucleoli
Vesicles Renal cancer:1.09e-5 (unfavourable) Expressed in all Expressed in all testis: 99.6 Expressed in all +BMPER CRIM3, Cv2 ENSG00000164619 BMP binding endothelial regulator 7 33904911-34155872 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA018083 Supported Tissue enhanced Mixed placenta: 9.5 Cell line enhanced fHDF/TERT166: 17.5;HBF TERT88: 23.1;hTEC/SVTERT24-B: 16.0;U-138 MG: 24.5 +RELL2 C5orf16, FLJ90583 ENSG00000164620 RELT like 2 5 141636950-141641077 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA077928 Uncertain Vesicles Mixed Tissue enhanced cerebral cortex: 13.2;parathyroid gland: 23.3 testis: 4.3 Mixed +KCNK5 K2p5.1, TASK-2 ENSG00000164626 Potassium two pore domain channel subfamily K member 5 6 39188973-39229450 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA059148 Uncertain Approved Nucleus Renal cancer:4.98e-7 (favourable), Cervical cancer:3.29e-4 (favourable), Urothelial cancer:4.45e-4 (favourable), Pancreatic cancer:5.85e-4 (unfavourable) Mixed Tissue enhanced small intestine: 39.3 gallbladder: 29.5 Cell line enhanced CACO-2: 28.9;HEL: 32.6;HMC-1: 28.2;K-562: 30.8 +KIF6 C6orf102, dJ1043E3.1, dJ137F1.4, dJ188D3.1, DKFZp451I2418, MGC33317 ENSG00000164627 Kinesin family member 6 6 39329990-39725405 Predicted intracellular proteins Evidence at protein level HPA038811, HPA058624 Enhanced Approved Centrosome Mixed Group enriched 6 cerebral cortex: 7.0;fallopian tube: 6.0;testis: 9.6 lung: 1.2 Cell line enhanced RPMI-8226: 6.3;SCLC-21H: 14.3;SK-MEL-30: 4.0 +ZNF12 GIOT-3, KOX3, ZNF325 ENSG00000164631 Zinc finger protein 12 7 6688433-6706923 Predicted intracellular proteins Evidence at protein level HPA063402 Supported Nucleoplasm
Centrosome Expressed in all Expressed in all parathyroid gland: 31.2 Expressed in all +SLC29A4 ENT4, FLJ34923 ENSG00000164638 Solute carrier family 29 member 4 7 5274369-5306870 Predicted membrane proteins, Transporters Evidence at protein level HPA052829 Supported Microtubules
Cytokinetic bridge Pancreatic cancer:4.52e-4 (favourable) Expressed in all Tissue enhanced adipose tissue: 44.2 cerebral cortex: 12.0 Cell line enhanced AN3-CA: 45.6;SH-SY5Y: 74.8 +C7orf62 MGC26647 ENSG00000164645 Chromosome 7 open reading frame 62 7 88794106-88795721 Predicted intracellular proteins Evidence at transcript level HPA023817, HPA024163 Uncertain Nucleoplasm
Mitochondria Not detected Tissue enriched 519 testis: 51.9 all non-specific tissues: 0.0 Not detected +STEAP1 PRSS24, STEAP ENSG00000164647 STEAP family member 1 7 90154375-90164829 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level HPA030985 Uncertain Tissue enriched Tissue enhanced prostate: 119.0 appendix: 40.6 Cell line enhanced CAPAN-2: 106.6;U-138 MG: 147.9 +CDCA7L JPO2, R1, RAM2 ENSG00000164649 Cell division cycle associated 7 like 7 21900900-21946084 Predicted intracellular proteins Evidence at protein level HPA027169 Approved Supported Nucleus
Nucleoli
Cytosol Liver cancer:4.36e-6 (unfavourable), Renal cancer:1.98e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 45.7 Mixed +SP8 ENSG00000164651 Sp8 transcription factor 7 20782283-20786886 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054006 Uncertain Approved Nucleus Tissue enhanced Tissue enriched 12 prostate: 10.5 skin: 0.8 Cell line enhanced HUVEC TERT2: 5.3;NTERA-2: 13.0;PC-3: 20.5 +MIOS FLJ20323, MIO, Sea4 ENSG00000164654 Meiosis regulator for oocyte development 7 7566872-7608929 Predicted intracellular proteins Evidence at protein level HPA042928, HPA052223 Approved Enhanced Nucleoplasm
Cytosol Renal cancer:3.28e-6 (favourable), Endometrial cancer:6.51e-4 (favourable), Liver cancer:9.14e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 54.8 Expressed in all +KIAA1324L EIG121L, FLJ31340 ENSG00000164659 KIAA1324 like 7 86876906-87059699 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044527, HPA076093 Uncertain Approved Endoplasmic reticulum Mixed Tissue enhanced lung: 32.2 cerebral cortex: 21.7 Cell line enhanced K-562: 44.1;SCLC-21H: 45.6 +USP49 MGC20741 ENSG00000164663 Ubiquitin specific peptidase 49 6 41789896-41895361 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030254, HPA030255 Uncertain Mixed Mixed testis: 9.1 Cell line enhanced REH: 42.8;U-698: 45.4 +SYTL3 exophilin-6, SLP3 ENSG00000164674 Synaptotagmin like 3 6 158650014-158764876 Predicted intracellular proteins Evidence at protein level HPA030584, HPA030585, HPA030586 Approved Approved Nucleoli fibrillar center
Vesicles Cervical cancer:8.84e-5 (favourable) Mixed Tissue enhanced thyroid gland: 44.5 fallopian tube: 22.9 Cell line enhanced HMC-1: 21.4;SCLC-21H: 19.1;U-2 OS: 20.9;U-266/70: 21.7 +IQUB FLJ35834 ENSG00000164675 IQ motif and ubiquitin domain containing 7 123452400-123535077 Predicted intracellular proteins Evidence at protein level HPA049626 Approved Nuclear speckles
Intermediate filaments
Cytosol Mixed Tissue enriched 8 testis: 66.3 fallopian tube: 8.2 Cell line enhanced RPTEC TERT1: 1.8 +HEY1 bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1 ENSG00000164683 Hes related family bHLH transcription factor with YRPW motif 1 8 79764010-79767863 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055599, HPA063472 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all Tissue enhanced cerebral cortex: 96.4 placenta: 28.8 Cell line enhanced HEK 293: 120.1;SK-MEL-30: 70.9 +ZNF704 FLJ16218, Gig1 ENSG00000164684 Zinc finger protein 704 8 80628451-80874781 Predicted intracellular proteins Evidence at protein level HPA024285, HPA024302 Uncertain Approved Nucleoplasm Renal cancer:4.02e-4 (favourable) Expressed in all Mixed parathyroid gland: 35.3 Cell line enhanced HaCaT: 63.8;RH-30: 44.5;SH-SY5Y: 61.9;SK-BR-3: 54.1 +FABP5 E-FABP, KFABP, PA-FABP ENSG00000164687 Fatty acid binding protein 5 8 81280363-81284777 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB017831, CAB040577, HPA051895 Enhanced Supported Plasma membrane
Cytosol Renal cancer:4.69e-10 (unfavourable) Expressed in all Expressed in all esophagus: 1664.2 Mixed +SHH HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS ENSG00000164690 Sonic hedgehog 7 155799986-155812273 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Endometrial cancer:8.62e-5 (favourable) Mixed Tissue enhanced adrenal gland: 12.0;stomach: 10.5;urinary bladder: 13.5 cervix, uterine: 6.8 Cell line enhanced CAPAN-2: 4.7;EFO-21: 8.5;PC-3: 3.8;RT4: 21.2 +TAGAP ARHGAP47, FLJ32631, IDDM21 ENSG00000164691 T-cell activation RhoGTPase activating protein 6 159034468-159045152 Predicted intracellular proteins Evidence at protein level HPA031000 Uncertain Expressed in all Tissue enhanced bone marrow: 129.8 lymph node: 55.5 Cell line enhanced Daudi: 27.0;HMC-1: 50.5;Karpas-707: 41.7;U-698: 34.9;U-937: 30.4 +COL1A2 OI4 ENSG00000164692 Collagen type I alpha 2 chain 7 94394561-94431232 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB032650, HPA059738 Approved Supported Endoplasmic reticulum Renal cancer:1.51e-9 (unfavourable) Expressed in all Expressed in all cervix, uterine: 2950.1 Cell line enhanced ASC diff: 2673.1;ASC TERT1: 3247.5;BJ: 3371.1;fHDF/TERT166: 10547.5;HSkMC: 2949.4 +FNDC1 bA243O10.1, dJ322A24.1, FNDC2, KIAA1866 ENSG00000164694 Fibronectin type III domain containing 1 6 159169397-159272109 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030962, HPA030963 Approved Supported Nuclear speckles Renal cancer:1.93e-6 (unfavourable), Endometrial cancer:6.10e-5 (favourable) Tissue enhanced Tissue enhanced gallbladder: 22.9;thyroid gland: 34.1 smooth muscle: 16.5 Cell line enhanced fHDF/TERT166: 2.3 +CHMP4C MGC22825, Shax3, VPS32C ENSG00000164695 Charged multivesicular body protein 4C 8 81732434-81759515 Predicted intracellular proteins Evidence at protein level HPA023799 Enhanced Renal cancer:1.96e-6 (favourable), Pancreatic cancer:6.99e-5 (unfavourable), Lung cancer:9.33e-5 (unfavourable), Urothelial cancer:6.45e-4 (favourable) Mixed Mixed duodenum: 41.8 Cell line enhanced CAPAN-2: 36.2;hTCEpi: 36.8 +SLC13A4 SUT-1, SUT1 ENSG00000164707 Solute carrier family 13 member 4 7 135681237-135729258 Predicted membrane proteins, Transporters Evidence at transcript level HPA048582 Approved Mixed Tissue enriched 10 placenta: 76.8 testis: 7.4 Cell line enriched 6 HDLM-2: 28.0 +PGAM2 PGAM-M ENSG00000164708 Phosphoglycerate mutase 2 7 44062727-44065587 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA050314, HPA060173 Enhanced Approved Nucleoplasm
Cytosol Not detected Group enriched 8 heart muscle: 521.3;skeletal muscle: 1459.5 testis: 126.6 Cell line enriched 10 SCLC-21H: 77.0 +BRI3 ENSG00000164713 Brain protein I3 7 98252379-98310441 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042215 Uncertain Head and neck cancer:3.35e-4 (unfavourable) Expressed in all Expressed in all lung: 119.1 Expressed in all +LMTK2 AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100 ENSG00000164715 Lemur tyrosine kinase 2 7 98106885-98209633 Enzymes, Predicted membrane proteins Evidence at protein level HPA010657, HPA041836 Uncertain Approved Nuclear speckles
Plasma membrane
Microtubule organizing center
Cytosol Renal cancer:1.12e-7 (favourable), Ovarian cancer:8.03e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 27.9 Expressed in all +SLC35G3 AMAC1, FLJ40154, TMEM21A ENSG00000164729 Solute carrier family 35 member G3 17 35192520-35194523 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Tissue enriched 15 testis: 1.6 lymph node,skeletal muscle,spleen: 0.1 Not detected +CTSB ENSG00000164733 Cathepsin B 8 11842524-11869448 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000457, HPA018156 Uncertain Supported Nucleoli
Vesicles Thyroid cancer:5.76e-4 (favourable), Urothelial cancer:9.02e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 2894.5 Expressed in all +SOX17 ENSG00000164736 SRY-box 17 8 54457935-54460888 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB025594, HPA068399 Enhanced Approved Nucleoplasm Endometrial cancer:2.76e-4 (favourable) Group enriched Tissue enhanced cervix, uterine: 30.2;endometrium: 32.2;fallopian tube: 30.1 adipose tissue: 14.7 Cell line enriched 8 EFO-21: 102.6 +DLC1 ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12 ENSG00000164741 DLC1 Rho GTPase activating protein 8 13083361-13604610 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017753 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Endometrial cancer:1.11e-4 (favourable) Expressed in all Expressed in all lung: 78.7 Cell line enhanced U-2197: 120.6 +ADCY1 AC1, DFNB44 ENSG00000164742 Adenylate cyclase 1 7 45574140-45723116 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB018364, HPA068274 Uncertain Approved Mitochondria Mixed Tissue enhanced cerebral cortex: 35.0 cervix, uterine: 8.2 Cell line enhanced hTERT-HME1: 17.5;SCLC-21H: 16.1;SH-SY5Y: 27.5;SK-MEL-30: 23.8;WM-115: 17.1 +C8orf48 FLJ25402 ENSG00000164743 Chromosome 8 open reading frame 48 8 13566843-13568287 Predicted intracellular proteins Evidence at protein level HPA025068, HPA026107, HPA027431, HPA027440 Approved Approved Nucleoplasm
Cytosol Mixed Tissue enhanced testis: 12.4 thyroid gland: 7.3 Cell line enhanced U-87 MG: 11.0;WM-115: 8.6 +SUN3 MGC33329, SUNC1 ENSG00000164744 Sad1 and UNC84 domain containing 3 7 47987148-48029119 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008344 Approved Golgi apparatus Tissue enhanced Tissue enriched 156 testis: 74.6 placenta: 0.4 Cell line enriched 8 U-2 OS: 21.7 +C7orf57 ENSG00000164746 Chromosome 7 open reading frame 57 7 48035511-48061304 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021286 Enhanced Mixed Tissue enhanced fallopian tube: 22.0;testis: 6.8 lung: 3.4 Cell line enhanced hTERT-HME1: 4.2;U-266/70: 2.4 +HNF4G NR2A2 ENSG00000164749 Hepatocyte nuclear factor 4 gamma 8 75407914-75566843 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005438 Enhanced Mixed Group enriched 5 duodenum: 100.2;small intestine: 125.6 rectum: 21.0 Cell line enhanced A549: 3.8;CAPAN-2: 13.9;PC-3: 4.4 +PEX2 PAF-1, PMP35, PXMP3, RNF72, ZWS3 ENSG00000164751 Peroxisomal biogenesis factor 2 8 76980258-77001044 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA010983, HPA011410, HPA027729 Approved Supported Vesicles Expressed in all Expressed in all seminal vesicle: 111.5 Expressed in all +RAD21 hHR21, KIAA0078, SCC1 ENSG00000164754 RAD21 cohesin complex component 8 116845935-116874866 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020044, CAB022065 Supported Enhanced Nucleoplasm Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all testis: 162.4 Expressed in all +SLC30A8 ZnT-8, ZNT8 ENSG00000164756 Solute carrier family 30 member 8 8 116950273-117176714 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA076165 Enhanced Group enriched Tissue enhanced pancreas: 13.2 salivary gland: 4.9 Group enriched 27 U-266/70: 36.7;U-266/84: 25.2 +MED30 THRAP6, TRAP25 ENSG00000164758 Mediator complex subunit 30 8 117520713-117540262 Predicted intracellular proteins Evidence at protein level HPA045767 Approved Nucleoplasm Renal cancer:1.70e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 27.8 Expressed in all +TNFRSF11B OCIF, OPG, TR1 ENSG00000164761 TNF receptor superfamily member 11b 8 118923557-118952200 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB034939 Approved Urothelial cancer:3.88e-4 (unfavourable), Cervical cancer:6.22e-4 (unfavourable), Renal cancer:6.79e-4 (favourable) Expressed in all Tissue enriched 5 thyroid gland: 140.4 kidney: 25.7 Cell line enhanced BJ: 369.9;BJ hTERT+: 1312.6;fHDF/TERT166: 188.6 +SBSPON C8orf84, RPESP ENSG00000164764 Somatomedin B and thrombospondin type 1 domain containing 8 73064540-73124088 Predicted secreted proteins Evidence at protein level HPA029595, CAB034214, CAB034332 Uncertain Approved Vesicles Breast cancer:7.18e-4 (favourable), Renal cancer:8.82e-4 (unfavourable) Mixed Tissue enhanced prostate: 23.8 urinary bladder: 16.2 Group enriched 6 BJ: 7.6;RPTEC TERT1: 12.1 +PHKG1 PHKG ENSG00000164776 Phosphorylase kinase catalytic subunit gamma 1 7 56080283-56092996 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012057 Enhanced Tissue enriched Tissue enriched 7 skeletal muscle: 100.5 cerebral cortex: 14.2 Mixed +EN2 ENSG00000164778 Engrailed homeobox 2 7 155458129-155464831 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045646, HPA069809 Supported Nucleus
Nucleoli fibrillar center Glioma:2.82e-6 (unfavourable) Tissue enhanced Tissue enhanced parathyroid gland: 2.0;testis: 1.1 endometrium: 0.6 Cell line enhanced AF22: 40.5;AN3-CA: 14.1;HEK 293: 23.0 +KCNV1 Kv8.1 ENSG00000164794 Potassium voltage-gated channel modifier subfamily V member 1 8 109963645-109975847 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Tissue enhanced Tissue enriched 32 cerebral cortex: 21.8 epididymis,skin,thyroid gland: 0.6 Not detected +CSMD3 ENSG00000164796 CUB and Sushi multiple domains 3 8 112222928-113437099 Predicted membrane proteins Evidence at transcript level HPA029007 Uncertain Not detected Group enriched 7 cerebral cortex: 4.9;testis: 1.8 fallopian tube,prostate,spleen: 0.4 Not detected +SPIDR KIAA0146 ENSG00000164808 Scaffolding protein involved in DNA repair 8 47260575-47736306 Predicted intracellular proteins Evidence at protein level HPA027201, HPA041582 Approved Supported Nucleoplasm Renal cancer:2.04e-6 (unfavourable), Ovarian cancer:8.91e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 30.7 Expressed in all +ORC5 ORC5L, Orc5p, ORC5T, PPP1R117 ENSG00000164815 Origin recognition complex subunit 5 7 104126341-104208047 Predicted intracellular proteins Evidence at protein level HPA019730 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all testis: 34.4 Expressed in all +DEFA5 DEF5, HD-5 ENSG00000164816 Defensin alpha 5 8 7055304-7056734 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA015775, CAB069919 Enhanced Colorectal cancer:9.44e-5 (favourable) Tissue enhanced Group enriched 480 duodenum: 10677.9;small intestine: 19102.0 appendix: 31.0 Group enriched 6 BEWO: 55.6;NB-4: 31.4;RPMI-8226: 35.9;SH-SY5Y: 42.9;U-2197: 16.2 +DNAAF5 CILD18, FLJ20397, FLJ25564, FLJ31671, FLJ39381, HEATR2 ENSG00000164818 Dynein axonemal assembly factor 5 7 726701-786475 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020243 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:3.83e-4 (unfavourable), Head and neck cancer:8.42e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 22.8 Expressed in all +DEFA4 DEF4, HP-4 ENSG00000164821 Defensin alpha 4 8 6935822-6938338 Predicted secreted proteins Evidence at protein level HPA051266 Enhanced Not detected Tissue enriched 640 bone marrow: 3105.2 spleen: 4.8 Cell line enriched 8 THP-1: 8.6 +DEFA6 DEF6, HD-6 ENSG00000164822 Defensin alpha 6 8 6924693-6926076 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA019462 Enhanced Tissue enhanced Group enriched 525 duodenum: 5743.0;small intestine: 10524.2 colon: 15.4 Group enriched 9 BEWO: 28.1;NB-4: 20.0;RPMI-8226: 25.8;SH-SY5Y: 26.0;U-2197: 10.6 +OSGIN2 C8orf1, hT41 ENSG00000164823 Oxidative stress induced growth inhibitor family member 2 8 89901859-89927888 Predicted intracellular proteins Evidence at transcript level HPA028515, HPA050595 Approved Approved Nucleoli Liver cancer:3.91e-6 (unfavourable), Lung cancer:2.93e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 88.9 Expressed in all +DEFB1 BD1, DEFB-1, DEFB101, HBD-1, HBD1, MGC51822 ENSG00000164825 Defensin beta 1 8 6870575-6878022 Predicted secreted proteins, Transporters Evidence at protein level Renal cancer:1.90e-5 (favourable), Lung cancer:5.62e-4 (unfavourable), Pancreatic cancer:5.94e-4 (unfavourable) Tissue enhanced Tissue enhanced cervix, uterine: 618.9;kidney: 1500.2 salivary gland: 232.3 Cell line enhanced NB-4: 34.9;SCLC-21H: 45.7;THP-1: 129.4 +SUN1 FLJ12407, KIAA0810, UNC84A ENSG00000164828 Sad1 and UNC84 domain containing 1 7 816615-896435 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA008346, HPA008461 Enhanced Enhanced Nuclear membrane Expressed in all Expressed in all endometrium: 120.7 Expressed in all +OXR1 TLDC3 ENSG00000164830 Oxidation resistance 1 8 106359476-106752694 Predicted intracellular proteins Evidence at protein level HPA027375, HPA027380, HPA027395 Enhanced Supported Vesicles Renal cancer:5.82e-5 (favourable), Pancreatic cancer:3.85e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 110.7 Expressed in all +TMEM74 FLJ30668, NET36 ENSG00000164841 Transmembrane protein 74 8 108606850-108787615 Predicted membrane proteins Evidence at protein level HPA015672 Uncertain Approved Cytosol Mixed Tissue enhanced cerebral cortex: 6.2 heart muscle: 1.6 Cell line enhanced HEK 293: 3.6;NTERA-2: 4.9;SCLC-21H: 12.4 +GPR146 PGR8 ENSG00000164849 G protein-coupled receptor 146 7 1044576-1059261 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Mixed Expressed in all adipose tissue: 33.6 Cell line enhanced BEWO: 22.4 +GPER1 CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR ENSG00000164850 G protein-coupled estrogen receptor 1 7 1082208-1093815 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA027052 Approved Endometrial cancer:1.17e-4 (favourable) Expressed in all Mixed placenta: 9.1 Cell line enhanced AN3-CA: 10.6;Hep G2: 15.3 +UNCX Uncx4.1 ENSG00000164853 UNC homeobox 7 1232907-1237318 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA063294 Approved Nucleoplasm Not detected Not detected kidney: 0.4 Cell line enriched 16 NB-4: 63.3 +TMEM184A MGC9712, SDMG1 ENSG00000164855 Transmembrane protein 184A 7 1542235-1560821 Predicted membrane proteins Evidence at protein level HPA053790, HPA071312 Uncertain Approved Nucleoplasm Colorectal cancer:1.12e-4 (unfavourable), Thyroid cancer:9.94e-4 (unfavourable) Mixed Tissue enhanced skin: 33.5 esophagus: 26.5 Cell line enhanced SCLC-21H: 43.0;SK-BR-3: 42.7;T-47d: 47.5 +NOS3 ECNOS, eNOS ENSG00000164867 Nitric oxide synthase 3 7 150990995-151014588 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002168 Enhanced Renal cancer:3.63e-4 (unfavourable) Expressed in all Tissue enriched 7 spleen: 71.8 adipose tissue: 10.6 Cell line enhanced BEWO: 22.3;HUVEC TERT2: 37.6;TIME: 67.7 +SPAG11B EDDM2B, EP2, EP2C, EP2D, HE2 ENSG00000164871 Sperm associated antigen 11B 8 7442684-7463674 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023842 Supported Not detected Tissue enriched 5739 epididymis: 6744.6 seminal vesicle: 1.1 Group enriched 7 BEWO: 3.9;NB-4: 5.5;RPMI-8226: 2.2;SH-SY5Y: 3.8 +MICALL2 FLJ23471, JRAB, MGC46023, MICAL-L2 ENSG00000164877 MICAL like 2 7 1428465-1459502 Predicted intracellular proteins Evidence at protein level HPA025695 Enhanced Renal cancer:6.53e-9 (unfavourable) Expressed in all Mixed small intestine: 17.5 Cell line enhanced HMC-1: 23.3 +CA3 CAIII, Car3 ENSG00000164879 Carbonic anhydrase 3 8 85373436-85449040 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004967, HPA021775, HPA026700 Enhanced Breast cancer:4.24e-6 (favourable) Group enriched Tissue enriched 13 skeletal muscle: 1838.7 prostate: 138.3 Group enriched 34 HEL: 44.2;RH-30: 77.2 +INTS1 DKFZp586J0619, INT1, KIAA1440, NET28 ENSG00000164880 Integrator complex subunit 1 7 1470277-1504367 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021658, HPA053009 Approved Approved Nucleoplasm Liver cancer:1.66e-4 (unfavourable), Pancreatic cancer:4.83e-4 (favourable) Expressed in all Expressed in all testis: 41.8 Expressed in all +CDK5 PSSALRE ENSG00000164885 Cyclin dependent kinase 5 7 151053812-151058530 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB008909, HPA064535 Enhanced Supported Nucleus
Plasma membrane
Cell Junctions Expressed in all Expressed in all cerebral cortex: 49.9 Expressed in all +SLC4A2 AE2, BND3L, EPB3L1, HKB3, NBND3 ENSG00000164889 Solute carrier family 4 member 2 7 151057210-151076527 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA019339 Enhanced Approved Nuclear speckles
Plasma membrane
Cytosol Liver cancer:9.04e-6 (unfavourable), Renal cancer:1.26e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 89.3 Expressed in all +SLC7A13 AGT-1, XAT2 ENSG00000164893 Solute carrier family 7 member 13 8 86214052-86321146 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Tissue enriched 170 kidney: 42.9 breast,testis: 0.2 Not detected +FASTK FAST ENSG00000164896 Fas activated serine/threonine kinase 7 151076593-151080866 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031621, CAB032539 Approved Approved Nuclear speckles
Mitochondria Pancreatic cancer:3.99e-4 (favourable), Colorectal cancer:4.73e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 41.7 Expressed in all +TMUB1 C7orf21, SB144 ENSG00000164897 Transmembrane and ubiquitin like domain containing 1 7 151081080-151083546 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA029429 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all small intestine: 52.2 Expressed in all +FMC1 C7orf55, HSPC268 ENSG00000164898 Formation of mitochondrial complex V assembly factor 1 homolog 7 139339457-139346319 Predicted intracellular proteins Evidence at protein level HPA045663, HPA050553 Approved Approved Mitochondria Ovarian cancer:5.63e-6 (favourable), Renal cancer:2.05e-5 (favourable), Lung cancer:1.08e-4 (favourable) Expressed in all Expressed in all prostate: 12.8 Expressed in all +GBX1 ENSG00000164900 Gastrulation brain homeobox 1 7 151148589-151174745 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055783 Uncertain Tissue enhanced Group enriched 57 skeletal muscle: 4.4;testis: 6.9 all non-specific tissues: 0.0 Cell line enhanced HMC-1: 1.4 +PHAX FLJ13193, RNUXA ENSG00000164902 Phosphorylated adaptor for RNA export 5 126600268-126627252 Predicted intracellular proteins, Transporters Evidence at protein level HPA059630, HPA070326 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all cerebral cortex: 17.8 Expressed in all +ALDH7A1 ATQ1, EPD, PDE ENSG00000164904 Aldehyde dehydrogenase 7 family member A1 5 126531200-126595418 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA023296 Enhanced Supported Mitochondria
Cytosol Renal cancer:3.08e-4 (favourable) Expressed in all Expressed in all kidney: 120.6 Mixed +FOXK1 IMAGE:5164497 ENSG00000164916 Forkhead box K1 7 4682309-4771443 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA017998, HPA018864 Enhanced Supported Nucleoplasm
Nucleoli fibrillar center Liver cancer:2.54e-6 (unfavourable) Expressed in all Mixed cerebral cortex: 12.4 Expressed in all +COX6C ENSG00000164919 Cytochrome c oxidase subunit 6C 8 99873200-99894062 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA014295, CAB016244 Enhanced Enhanced Mitochondria Expressed in all Expressed in all duodenum: 339.6 Expressed in all +OSR2 FLJ90037 ENSG00000164920 Odd-skipped related transciption factor 2 8 98944403-98952104 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052425, HPA063486 Uncertain Approved Nucleus
Plasma membrane Head and neck cancer:2.44e-5 (favourable) Mixed Tissue enhanced endometrium: 205.3;fallopian tube: 144.6 ovary: 102.9 Cell line enriched 13 ASC diff: 372.1 +YWHAZ 14-3-3-zeta, KCIP-1, YWHAD ENSG00000164924 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 8 100916525-100953388 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005065 Approved Renal cancer:2.03e-6 (unfavourable), Pancreatic cancer:1.20e-5 (unfavourable), Liver cancer:2.28e-5 (unfavourable), Endometrial cancer:3.91e-4 (unfavourable), Lung cancer:3.93e-4 (unfavourable) Expressed in all Expressed in all esophagus: 925.0 Expressed in all +BAALC ENSG00000164929 Brain and acute leukemia, cytoplasmic 8 103140710-103230305 Predicted intracellular proteins Evidence at protein level HPA027132, HPA068307 Approved Supported Nucleus
Cytosol Tissue enriched Tissue enriched 16 cerebral cortex: 247.7 adrenal gland: 15.6 Cell line enhanced AF22: 50.6;SCLC-21H: 32.7;SH-SY5Y: 21.7;U-87 MG: 73.6 +FZD6 Hfz6 ENSG00000164930 Frizzled class receptor 6 8 103298433-103332866 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA017991 Approved Approved Plasma membrane Pancreatic cancer:1.20e-6 (unfavourable) Expressed in all Mixed parathyroid gland: 45.5 Mixed +CTHRC1 ENSG00000164932 Collagen triple helix repeat containing 1 8 103371515-103382997 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059806, HPA061896 Approved Approved Nucleoplasm Renal cancer:1.22e-14 (unfavourable), Liver cancer:1.67e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 137.8;placenta: 125.5;urinary bladder: 100.0 breast: 49.2 Cell line enhanced ASC TERT1: 202.9;HHSteC: 162.6;HSkMC: 291.0;WM-115: 375.8 +SLC25A32 MFTC ENSG00000164933 Solute carrier family 25 member 32 8 103398635-103415189 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA024763, HPA047402 Uncertain Supported Mitochondria Renal cancer:1.53e-6 (unfavourable), Lung cancer:2.09e-4 (unfavourable), Endometrial cancer:7.23e-4 (unfavourable) Expressed in all Expressed in all gallbladder,lymph node: 21.0 Expressed in all +DCAF13 DKFZP564O0463, Gm83, HSPC064, WDSOF1 ENSG00000164934 DDB1 and CUL4 associated factor 13 8 103414714-103443453 Predicted intracellular proteins Evidence at protein level HPA044504 Uncertain Supported Nucleus
Nucleoli
Cell Junctions
Centrosome
Cytosol Liver cancer:8.05e-6 (unfavourable), Renal cancer:2.85e-4 (unfavourable), Breast cancer:4.06e-4 (unfavourable) Expressed in all Expressed in all testis: 58.8 Expressed in all +DCSTAMP DC-STAMP, FIND, TM7SF4 ENSG00000164935 Dendrocyte expressed seven transmembrane protein 8 104339087-104356689 Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Group enriched 10 epididymis: 2.4;lung: 5.6 cerebral cortex,cervix, uterine,lymph node,urinary bladder: 0.3 Not detected +TP53INP1 DKFZp434M1317, FLJ22139, P53DINP1, SIP, Teap, TP53INP1A, TP53INP1B ENSG00000164938 Tumor protein p53 inducible nuclear protein 1 8 94925972-94949411 Predicted intracellular proteins Evidence at protein level HPA005856 Uncertain Supported Cytosol Urothelial cancer:5.45e-5 (favourable), Head and neck cancer:1.11e-4 (favourable) Expressed in all Expressed in all testis: 52.8 Cell line enhanced Karpas-707: 57.1;U-266/70: 65.0 +INTS8 C8orf52, FLJ20530, INT8, MGC131633 ENSG00000164941 Integrator complex subunit 8 8 94813311-94881746 Predicted intracellular proteins Evidence at protein level HPA057299 Approved Approved Nucleoplasm Renal cancer:0.00e+0 (unfavourable), Liver cancer:2.54e-6 (unfavourable) Expressed in all Expressed in all testis: 57.3 Expressed in all +KIAA1429 DKFZP434I116, fSAP121 ENSG00000164944 KIAA1429 8 94487693-94553529 Predicted intracellular proteins Evidence at protein level HPA031530 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:7.90e-4 (unfavourable) Expressed in all Expressed in all testis: 30.2 Expressed in all +FREM1 C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR ENSG00000164946 FRAS1 related extracellular matrix 1 9 14734666-14910995 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced endometrium: 34.0;epididymis: 44.5 smooth muscle: 23.2 Cell line enriched 8 HEL: 162.3 +GEM KIR ENSG00000164949 GTP binding protein overexpressed in skeletal muscle 8 94249253-94262350 Predicted intracellular proteins Evidence at protein level HPA024798 Approved Renal cancer:1.56e-5 (unfavourable), Thyroid cancer:4.29e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 364.8 endometrium: 157.2 Cell line enhanced BJ hTERT+: 67.0;U-266/70: 106.3;U-87 MG: 102.0 +PDP1 PDH, PDP, PPM2A, PPM2C ENSG00000164951 Pyruvate dehyrogenase phosphatase catalytic subunit 1 8 93857807-93926066 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018483, HPA019081, HPA021152 Uncertain Supported Nucleoplasm
Mitochondria
Cytosol Renal cancer:8.42e-9 (favourable), Breast cancer:8.61e-5 (unfavourable), Ovarian cancer:5.60e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 82.3 Expressed in all +TMEM67 JBTS6, MGC26979, MKS3, NPHP11 ENSG00000164953 Transmembrane protein 67 8 93754844-93819234 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Renal cancer:7.62e-4 (unfavourable) Mixed Tissue enhanced fallopian tube: 21.5 testis: 12.5 Mixed +WASHC5 KIAA0196, SPG8 ENSG00000164961 WASH complex subunit 5 8 125024260-125091840 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034216, CAB034219, HPA064649, HPA070916 Enhanced Supported Nucleoplasm Liver cancer:6.74e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 39.6 Expressed in all +RPP25L bA296L22.5, C9orf23, MGC29635 ENSG00000164967 Ribonuclease P/MRP subunit p25 like 9 34610486-34612104 Predicted intracellular proteins Evidence at protein level HPA052187, HPA059698 Uncertain Supported Nucleus Renal cancer:3.01e-9 (favourable), Urothelial cancer:8.21e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 38.7 Expressed in all +FAM219A bA573M23.5, C9orf25, FLJ39031 ENSG00000164970 Family with sequence similarity 219 member A 9 34398184-34458570 Predicted intracellular proteins Evidence at protein level HPA019338, HPA052909 Uncertain Supported Nucleoplasm
Golgi apparatus
Vesicles Liver cancer:1.98e-5 (unfavourable), Renal cancer:5.54e-5 (unfavourable), Pancreatic cancer:2.46e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 76.1 Expressed in all +C9orf24 bA573M23.4, CBE1, MGC32921, MGC33614, NYD-SP22, SMRP1 ENSG00000164972 Chromosome 9 open reading frame 24 9 34379019-34397832 Predicted intracellular proteins Evidence at protein level HPA053008 Enhanced Endometrial cancer:3.23e-5 (favourable), Pancreatic cancer:1.75e-4 (favourable) Tissue enhanced Group enriched 11 fallopian tube: 173.9;testis: 65.3 lung: 10.9 Not detected +SNAPC3 MGC132011, MGC33124, PTFbeta, SNAP50 ENSG00000164975 Small nuclear RNA activating complex polypeptide 3 9 15422704-15465953 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053145, HPA066031 Supported Nucleus
Nucleoli
Nuclear bodies Expressed in all Mixed cerebral cortex: 11.9 Expressed in all +KIAA1161 NET37 ENSG00000164976 KIAA1161 9 34366670-34376853 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060533, HPA067487 Approved Approved Mitochondria Renal cancer:1.20e-13 (favourable), Endometrial cancer:6.96e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 29.4 Cell line enhanced SK-BR-3: 43.1;T-47d: 50.4 +NUDT2 APAH1 ENSG00000164978 Nudix hydrolase 2 9 34329506-34343713 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004684, HPA044903, HPA058623, HPA067639 Uncertain Enhanced Nucleoplasm Expressed in all Expressed in all epididymis: 43.6 Expressed in all +TMEM65 ENSG00000164983 Transmembrane protein 65 8 124306189-124372692 Predicted membrane proteins Evidence at protein level HPA025020 Uncertain Approved Nucleoplasm Endometrial cancer:1.05e-4 (unfavourable), Breast cancer:2.17e-4 (unfavourable), Liver cancer:2.56e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 17.6 Mixed +PSIP1 LEDGF, p52, p75, PSIP2 ENSG00000164985 PC4 and SFRS1 interacting protein 1 9 15464066-15511019 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013718, HPA019697 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all cerebral cortex: 161.3 Expressed in all +CCDC171 bA536D16.1, bA778P13.1, C9orf93, Em:AL513423.1, FLJ39267, FLJ46740 ENSG00000164989 Coiled-coil domain containing 171 9 15553086-16061663 Predicted intracellular proteins Evidence at protein level HPA019803, HPA019806, HPA024133 Uncertain Approved Nucleus Mixed Tissue enhanced testis: 20.7 endometrium: 9.7 Cell line enhanced HEL: 10.5 +UBAP1 UBAP ENSG00000165006 Ubiquitin associated protein 1 9 34179005-34252523 Predicted intracellular proteins Evidence at protein level HPA019804, HPA041590 Approved Enhanced Plasma membrane
Cytosol Renal cancer:7.49e-6 (favourable) Expressed in all Expressed in all testis: 88.6 Expressed in all +DIRAS2 Di-Ras2, DKFZp761C07121 ENSG00000165023 DIRAS family GTPase 2 9 90609832-90643105 Predicted intracellular proteins Evidence at protein level HPA043758 Uncertain Tissue enhanced Tissue enriched 9 cerebral cortex: 128.3 cervix, uterine: 13.9 Cell line enhanced AF22: 7.0;EFO-21: 1.9;SCLC-21H: 1.5 +SYK ENSG00000165025 Spleen associated tyrosine kinase 9 90801787-90898549 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA001384, CAB007773 Enhanced Approved Vesicles
Plasma membrane
Cytosol Expressed in all Mixed parathyroid gland: 96.0 Cell line enhanced Daudi: 89.3;HEL: 64.8;HL-60: 80.0;REH: 76.3 +NIPSNAP3B FLJ11275 ENSG00000165028 Nipsnap homolog 3B 9 104764157-104777457 Predicted intracellular proteins Evidence at protein level HPA042491 Uncertain Mixed Mixed adipose tissue: 15.6 Cell line enhanced REH: 3.9 +ABCA1 ABC1, HDLDT1, TGD ENSG00000165029 ATP binding cassette subfamily A member 1 9 104781002-104928237 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA057283, CAB069889 Approved Approved Nucleoplasm
Vesicles Expressed in all Mixed adrenal gland: 38.0 Cell line enhanced U-87 MG: 76.7 +NFIL3 E4BP4, IL3BP1, NF-IL3A, NFIL3A ENSG00000165030 Nuclear factor, interleukin 3 regulated 9 91409045-91423862 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003261 Approved Approved Nuclear bodies Renal cancer:3.23e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 137.2 Expressed in all +LETM2 FLJ25409 ENSG00000165046 Leucine zipper and EF-hand containing transmembrane protein 2 8 38386207-38409527 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA025032 Approved Approved Nucleus
Nuclear bodies
Cytosol Mixed Tissue enriched 9 testis: 39.5 cerebral cortex: 4.2 Mixed +METTL2B FLJ11350, METL, METTL2 ENSG00000165055 Methyltransferase like 2B 7 128476729-128506602 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all skin: 12.9 Expressed in all +PRKACG PKACg ENSG00000165059 Protein kinase cAMP-activated catalytic subunit gamma 9 69012529-69014113 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004530, HPA071185 Supported Approved Cytosol Not detected Tissue enriched 302 testis: 30.1 all non-specific tissues: 0.0 Not detected +FXN CyaY, FA, FARR, FRDA, X25 ENSG00000165060 Frataxin 9 69035259-69100178 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB022164, HPA068304 Supported Supported Mitochondria
Cytosol Expressed in all Expressed in all parathyroid gland: 34.1 Expressed in all +ZMAT4 FLJ13842 ENSG00000165061 Zinc finger matrin-type 4 8 40530590-40897833 Predicted intracellular proteins Evidence at protein level HPA056671, HPA069813 Enhanced Approved Intermediate filaments Thyroid cancer:3.51e-4 (unfavourable) Tissue enhanced Group enriched 8 cerebral cortex: 10.1;thyroid gland: 27.6 testis: 2.4 Group enriched 5 AF22: 22.3;U-2197: 13.1 +NKX6-3 FLJ25169 ENSG00000165066 NK6 homeobox 3 8 41645178-41650669 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA042790 Uncertain Group enriched Tissue enhanced duodenum: 17.3;stomach: 50.6 parathyroid gland: 7.3 Group enriched 7 Daudi: 4.2;THP-1: 1.8 +TMEM71 FLJ33069 ENSG00000165071 Transmembrane protein 71 8 132685007-132760712 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058401, HPA070655 Uncertain Enhanced Mitochondria Mixed Mixed heart muscle: 27.1 Cell line enhanced HDLM-2: 53.9;U-937: 26.7 +MAMDC2 MGC21981 ENSG00000165072 MAM domain containing 2 9 70043581-70226970 Predicted secreted proteins Evidence at protein level HPA021814, HPA022249 Uncertain Approved Nuclear speckles
Plasma membrane Thyroid cancer:7.78e-4 (unfavourable) Mixed Mixed endometrium: 60.6 Cell line enhanced ASC diff: 35.3;HHSteC: 44.9;LHCN-M2: 57.7;TIME: 54.7 +PRSS37 ENSG00000165076 Protease, serine 37 7 141836286-141841487 Enzymes, Predicted secreted proteins Evidence at protein level HPA020541 Enhanced Not detected Tissue enriched 162 testis: 55.3 skin: 0.3 Not detected +CPA6 CPAH ENSG00000165078 Carboxypeptidase A6 8 67422038-67746385 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced prostate: 4.9;rectum: 2.9 colon: 1.7 Cell line enhanced CACO-2: 2.9;EFO-21: 1.8;Hep G2: 3.6 +C8orf34 vest-1, VEST1 ENSG00000165084 Chromosome 8 open reading frame 34 8 68330722-68819022 Predicted intracellular proteins Evidence at protein level HPA044420, HPA053065 Uncertain Supported Nucleus
Nucleoli
Golgi apparatus Mixed Tissue enhanced fallopian tube: 14.7;parathyroid gland: 18.7 cerebral cortex: 6.1 Cell line enhanced HEK 293: 2.4;LHCN-M2: 1.9;RH-30: 2.3 +TMC1 DFNA36, DFNB11, DFNB7 ENSG00000165091 Transmembrane channel like 1 9 72521801-72836351 Disease related genes, Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced cervix, uterine: 1.6 placenta: 1.0 Cell line enhanced BEWO: 3.1;HAP1: 6.7;NTERA-2: 3.0;U-266/70: 1.6;U-266/84: 1.5 +ALDH1A1 ALDH1, PUMB1, RALDH1 ENSG00000165092 Aldehyde dehydrogenase 1 family member A1 9 72900662-73080442 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002123, CAB020690 Approved Approved Enhanced Cytosol Cervical cancer:7.77e-5 (favourable) Expressed in all Expressed in all liver: 760.0 Cell line enhanced A549: 3635.1;Hep G2: 855.5;RPTEC TERT1: 528.6 +KDM1B AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2 ENSG00000165097 Lysine demethylase 1B 6 18155329-18223853 Predicted intracellular proteins Evidence at protein level HPA031269 Uncertain Approved Nucleus Colorectal cancer:6.94e-4 (favourable) Expressed in all Expressed in all thyroid gland: 65.1 Expressed in all +HGSNAT FLJ32731, HGNAT, TMEM76 ENSG00000165102 Heparan-alpha-glucosaminide N-acetyltransferase 8 43140455-43202855 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA029578 Approved Ovarian cancer:6.33e-5 (favourable), Glioma:7.02e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 49.2 Expressed in all +RASEF FLJ31614, RAB45 ENSG00000165105 RAS and EF-hand domain containing 9 82979585-83063177 Predicted intracellular proteins Evidence at protein level HPA021431 Approved Microtubules Mixed Expressed in all thyroid gland: 44.6 Mixed +GKAP1 FKSG21, GKAP42 ENSG00000165113 G kinase anchoring protein 1 9 83739421-83829516 Predicted intracellular proteins Evidence at protein level HPA035117, HPA035118, HPA066173 Enhanced Approved Approved Microtubule organizing center
Cytosol Renal cancer:1.05e-6 (favourable), Pancreatic cancer:6.96e-5 (favourable) Mixed Tissue enriched 21 testis: 363.1 skeletal muscle: 17.6 Mixed +KIF27 DKFZp434D0917 ENSG00000165115 Kinesin family member 27 9 83836698-83921465 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced testis: 46.6 thyroid gland: 14.0 Mixed +C9orf64 MGC10999 ENSG00000165118 Chromosome 9 open reading frame 64 9 83938311-83956986 Predicted intracellular proteins Evidence at protein level HPA054903, HPA066190 Uncertain Approved Golgi apparatus Renal cancer:4.23e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.4 Mixed +HNRNPK CSBP, HNRPK, TUNP ENSG00000165119 Heterogeneous nuclear ribonucleoprotein K 9 83968083-83980616 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004435, HPA007644, CAB016225, HPA044105 Supported Enhanced Nucleoplasm Liver cancer:6.68e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 528.1 Expressed in all +SSMEM1 C7orf45, FLJ40316 ENSG00000165120 Serine rich single-pass membrane protein 1 7 130207860-130216843 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 199 testis: 57.1 lung,placenta: 0.2 Not detected +SVEP1 bA427L11.3, C9orf13, FLJ13529, POLYDOM ENSG00000165124 Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 9 110365251-110579880 Predicted secreted proteins Evidence at protein level HPA020610, HPA021520 Uncertain Stomach cancer:8.33e-4 (unfavourable) Mixed Tissue enhanced placenta: 87.2 adipose tissue: 36.7 Cell line enhanced ASC diff: 101.0;ASC TERT1: 59.3;BJ hTERT+: 50.6;HHSteC: 45.2;HSkMC: 48.5 +TRPV6 CaT1, ECAC2 ENSG00000165125 Transient receptor potential cation channel subfamily V member 6 7 142871203-142885762 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA062864 Approved Tissue enriched Tissue enhanced prostate: 37.4;salivary gland: 28.9 placenta: 16.7 Cell line enhanced HaCaT: 16.0;RT4: 26.0;SK-BR-3: 17.7;T-47d: 49.5 +C7orf34 CTM-1 ENSG00000165131 Chromosome 7 open reading frame 34 7 142939343-142940868 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 40 testis: 41.5 bone marrow: 1.0 Not detected +ANKS6 ANKRD14, FLJ36928, NPHP16, SAMD6 ENSG00000165138 Ankyrin repeat and sterile alpha motif domain containing 6 9 98731329-98796965 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008355 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:3.44e-5 (favourable) Expressed in all Mixed thyroid gland: 15.3 Mixed +FBP1 FBP ENSG00000165140 Fructose-bisphosphatase 1 9 94603133-94640249 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005857, HPA012513, CAB033869 Enhanced Uncertain Mitochondria Renal cancer:6.86e-7 (favourable), Urothelial cancer:1.64e-5 (favourable), Liver cancer:1.79e-4 (favourable), Endometrial cancer:5.16e-4 (favourable) Expressed in all Tissue enhanced liver: 443.9 duodenum: 329.6 Cell line enhanced HaCaT: 66.7;MCF7: 184.8;RT4: 124.5;U-698: 78.4 +TMEM246 C9orf125, MGC12992 ENSG00000165152 Transmembrane protein 246 9 101473171-101533537 Predicted membrane proteins Evidence at protein level HPA011318, HPA054041 Uncertain Approved Mitochondria Renal cancer:1.55e-8 (favourable) Mixed Mixed cerebral cortex: 46.5 Mixed +ZHX1 ENSG00000165156 Zinc fingers and homeoboxes 1 8 123248451-123275541 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055357, HPA060251 Enhanced Nucleoplasm Endometrial cancer:6.09e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 62.9 Expressed in all +CFAP47 CHDC2, CXorf22, CXorf30, CXorf59, FLJ36601, MGC34831, RP13-11B7.1 ENSG00000165164 Cilia and flagella associated protein 47 X 35919734-36385319 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA044633, HPA054859 Uncertain Tissue enhanced Tissue enriched 5 fallopian tube: 7.5 testis: 1.3 Group enriched 6 Karpas-707: 1.1;U-266/70: 2.2 +CYBB CGD, GP91-PHOX, NOX2 ENSG00000165168 Cytochrome b-245 beta chain X 37780011-37813461 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA051227 Enhanced Expressed in all Tissue enhanced appendix: 215.6 lung: 132.2 Group enriched 5 Daudi: 37.3;NB-4: 40.0;REH: 49.1;RPMI-8226: 143.6 +DYNLT3 TCTE1L, TCTEX1L ENSG00000165169 Dynein light chain Tctex-type 3 X 37836757-37847637 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003938 Approved Glioma:4.22e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 77.2 Mixed +WBSCR27 ENSG00000165171 Williams Beuren syndrome chromosome region 27 7 73834590-73842535 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA022420 Uncertain Supported Focal adhesion sites Renal cancer:1.10e-6 (favourable), Colorectal cancer:1.73e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 8.4 Cell line enhanced RPMI-8226: 54.9;T-47d: 21.0 +MID1IP1 FLJ10386, G12-like, MIG12, STRAIT11499, THRSPL ENSG00000165175 MID1 interacting protein 1 X 38801432-38806537 Predicted intracellular proteins Evidence at protein level HPA038816 Uncertain Renal cancer:1.15e-4 (favourable), Liver cancer:2.20e-4 (unfavourable), Urothelial cancer:8.06e-4 (favourable) Expressed in all Expressed in all bone marrow: 66.2 Expressed in all +C9orf84 FLJ32779 ENSG00000165181 Chromosome 9 open reading frame 84 9 111686173-111795008 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA032108 Approved Vesicles
Cytosol Mixed Tissue enriched 10 testis: 31.0 adrenal gland: 3.1 Cell line enhanced A-431: 4.3;SiHa: 5.3;U-2 OS: 23.4;U-266/84: 3.3 +CXorf58 FLJ25444 ENSG00000165182 Chromosome X open reading frame 58 X 23907801-23939507 Predicted intracellular proteins Evidence at protein level HPA031542, HPA031543, HPA031544 Uncertain Not detected Tissue enriched 9 testis: 6.2 fallopian tube: 0.6 Not detected +KIAA1958 FLJ39294 ENSG00000165185 KIAA1958 9 112486847-112669397 Predicted intracellular proteins Evidence at protein level HPA020625 Enhanced Approved Plasma membrane
Cytosol Mixed Mixed ovary: 12.2 Mixed +PTCHD1 FLJ30296 ENSG00000165186 Patched domain containing 1 X 23334016-23404372 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA046110 Uncertain Mixed Tissue enhanced cerebral cortex: 4.6;seminal vesicle: 5.1 endometrium: 2.6 Cell line enhanced HEK 293: 1.5;RT4: 1.3;WM-115: 5.3 +RNF183 MGC4734 ENSG00000165188 Ring finger protein 183 9 113297093-113303376 Enzymes, Predicted membrane proteins Evidence at protein level HPA057675 Uncertain Endometrial cancer:7.95e-6 (favourable), Renal cancer:3.51e-4 (favourable) Tissue enhanced Tissue enhanced epididymis: 20.0;gallbladder: 9.0 kidney: 4.3 Cell line enriched 10 SCLC-21H: 22.2 +ASB11 DKFZp779E2460 ENSG00000165192 Ankyrin repeat and SOCS box containing 11 X 15281697-15315656 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000238 Uncertain Tissue enriched Group enriched 6 heart muscle: 30.6;skeletal muscle: 42.1 stomach: 5.8 Not detected +PCDH19 EFMR, EIEE9, KIAA1313 ENSG00000165194 Protocadherin 19 X 100291644-100410273 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027533 Approved Approved Cytosol Mixed Tissue enhanced cerebral cortex: 11.3 cervix, uterine: 2.6 Cell line enriched 7 AF22: 17.7 +PIGA GPI3 ENSG00000165195 Phosphatidylinositol glycan anchor biosynthesis class A X 15319451-15335580 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001174 Approved Pancreatic cancer:7.64e-4 (unfavourable) Expressed in all Mixed lung: 9.8 Expressed in all +VEGFD FIGF, VEGF-D ENSG00000165197 Vascular endothelial growth factor D X 15345591-15384376 Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA027342 Uncertain Mixed Tissue enhanced breast: 25.0;lung: 59.3 adipose tissue: 13.2 Cell line enhanced ASC diff: 2.3;ASC TERT1: 2.0;HSkMC: 2.1 +OR1Q1 HSTPCR106, OR1Q2, OR1Q3, OR9-A, OST226, OST226OR9-A, TPCR106 ENSG00000165202 Olfactory receptor family 1 subfamily Q member 1 9 122614738-122615682 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA044828 Uncertain Not detected Not detected epididymis: 0.9 Not detected +OR1K1 hg99, MNAB ENSG00000165204 Olfactory receptor family 1 subfamily K member 1 9 122800123-122801073 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.2 Not detected +STRBP FLJ11307, ILF3L, SPNR ENSG00000165209 Spermatid perinuclear RNA binding protein 9 123109500-123268576 Predicted intracellular proteins Evidence at protein level HPA020651 Approved Renal cancer:1.70e-10 (favourable), Liver cancer:8.18e-4 (unfavourable) Expressed in all Expressed in all testis: 79.0 Mixed +CLDN3 C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 ENSG00000165215 Claudin 3 7 73768997-73770270 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB002702, HPA014361 Supported Supported Cell Junctions Renal cancer:3.39e-5 (favourable) Mixed Tissue enhanced colon: 87.7;small intestine: 119.5 duodenum: 55.0 Cell line enhanced MCF7: 175.3;PC-3: 44.1;SCLC-21H: 68.2;T-47d: 98.9 +GAPVD1 DKFZP434C212, KIAA1521 ENSG00000165219 GTPase activating protein and VPS9 domains 1 9 125261794-125367207 Predicted intracellular proteins Evidence at protein level HPA029386, HPA029387 Uncertain Supported Cytosol Expressed in all Expressed in all testis: 49.2 Expressed in all +CARD19 bA370F5.1, BinCARD, C9orf89, MGC11115 ENSG00000165233 Caspase recruitment domain family member 19 9 93096218-93113283 Predicted membrane proteins Evidence at protein level HPA010921, HPA010990, HPA038297 Approved Supported Mitochondria Liver cancer:1.32e-5 (unfavourable), Glioma:6.41e-5 (unfavourable) Expressed in all Mixed testis: 11.1 Expressed in all +WNK2 KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43 ENSG00000165238 WNK lysine deficient protein kinase 2 9 93184916-93320572 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015555, HPA016519, CAB017813 Enhanced Approved Cytosol Mixed Mixed heart muscle: 29.1 Cell line enhanced Hep G2: 21.0;SCLC-21H: 44.2 +ATP7A MNK ENSG00000165240 ATPase copper transporting alpha X 77910656-78050395 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA012887, HPA048107 Approved Supported Golgi apparatus
Vesicles Renal cancer:8.38e-4 (favourable) Expressed in all Mixed parathyroid gland: 15.3 Mixed +ZNF367 FLJ33970 ENSG00000165244 Zinc finger protein 367 9 96385941-96418329 Predicted intracellular proteins Evidence at protein level HPA015319, HPA015785 Uncertain Supported Nucleoplasm Thyroid cancer:2.34e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 16.0 testis: 11.2 Mixed +NLGN4Y KIAA0951 ENSG00000165246 Neuroligin 4, Y-linked Y 14522638-14845650 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA001651 Approved Mixed Tissue enhanced prostate: 11.4;seminal vesicle: 12.5 cerebral cortex: 7.5 Cell line enhanced BJ hTERT+: 28.5;fHDF/TERT166: 21.5;HDLM-2: 30.2;hTCEpi: 16.2;U-138 MG: 23.0 +HDX CXorf43, FLJ30678 ENSG00000165259 Highly divergent homeobox X 84317874-84502479 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047189 Uncertain Approved Cytosol Mixed Mixed cerebral cortex,endometrium: 3.8 Mixed +NDUFB6 B17, CI ENSG00000165264 NADH:ubiquinone oxidoreductase subunit B6 9 32552999-32573184 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044001, HPA053334 Supported Enhanced Mitochondria Renal cancer:7.47e-10 (favourable), Cervical cancer:3.18e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 70.2 Expressed in all +AQP7 AQP7L, AQP9, AQPap ENSG00000165269 Aquaporin 7 9 33383179-33402682 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:9.21e-8 (favourable) Mixed Tissue enriched 5 adipose tissue: 355.1 parathyroid gland: 66.5 Cell line enriched 49 ASC diff: 181.4 +NOL6 bA311H10.1, FLJ21959, MGC14896, MGC14921, MGC20838, Nrap, UTP22 ENSG00000165271 Nucleolar protein 6 9 33461441-33473930 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055891, HPA061002 Supported Enhanced Nucleus
Nucleoli
Mitochondria Liver cancer:4.83e-5 (unfavourable), Thyroid cancer:9.49e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.7 Expressed in all +AQP3 GIL ENSG00000165272 Aquaporin 3 (Gill blood group) 9 33441154-33447611 Blood group antigen proteins, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA014924 Enhanced Supported Nucleus
Plasma membrane Cervical cancer:5.31e-4 (favourable) Expressed in all Expressed in all esophagus: 971.6 Cell line enhanced HaCaT: 113.2;HeLa: 108.6;RT4: 167.6;SK-BR-3: 112.0;U-266/70: 114.3;U-266/84: 148.6 +TRMT10B bA3J10.9, FLJ31455, RG9MTD3 ENSG00000165275 TRNA methyltransferase 10B 9 37753803-37778972 Predicted intracellular proteins Evidence at transcript level HPA021800 Uncertain Approved Nucleoplasm
Plasma membrane Lung cancer:3.91e-4 (favourable), Pancreatic cancer:5.34e-4 (favourable) Expressed in all Mixed skin: 12.9 Expressed in all +VCP IBMPFD, p97 ENSG00000165280 Valosin containing protein 9 35056064-35073249 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level CAB005593, HPA012728, HPA012814 Supported Enhanced Nucleoplasm
Cytosol Renal cancer:9.63e-7 (favourable), Endometrial cancer:7.30e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 94.2 Expressed in all +PIGO DKFZp434M222, FLJ00135 ENSG00000165282 Phosphatidylinositol glycan anchor biosynthesis class O 9 35088688-35096601 Disease related genes, Predicted membrane proteins Evidence at protein level HPA014905 Approved Nucleus
Nucleoli Renal cancer:3.05e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 74.6 Expressed in all +STOML2 HSPC108, SLP-2 ENSG00000165283 Stomatin like 2 9 35099776-35103195 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB015944, HPA062016 Supported Supported Plasma membrane
Cytosol Renal cancer:3.00e-5 (favourable), Liver cancer:4.77e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 98.6 Expressed in all +BRWD3 FLJ38568, MRX93 ENSG00000165288 Bromodomain and WD repeat domain containing 3 X 80670854-80809688 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA012802 Approved Approved Nucleoplasm
Cytosol Expressed in all Mixed testis: 8.6 Mixed +SLITRK5 bA364G4.2, KIAA0918, LRRC11 ENSG00000165300 SLIT and NTRK like family member 5 13 87672615-87696272 Predicted membrane proteins Evidence at protein level HPA013843 Uncertain Supported Nucleoplasm
Golgi apparatus Not detected Tissue enhanced cerebral cortex: 4.9;fallopian tube: 4.7 seminal vesicle: 1.8 Cell line enhanced AF22: 6.9 +MELK KIAA0175 ENSG00000165304 Maternal embryonic leucine zipper kinase 9 36572862-36677683 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017214 Uncertain Renal cancer:0.00e+0 (unfavourable), Liver cancer:2.91e-7 (unfavourable), Lung cancer:3.99e-4 (unfavourable), Pancreatic cancer:4.58e-4 (unfavourable) Expressed in all Tissue enhanced testis: 16.9 lymph node: 11.7 Expressed in all +ARMC3 CT81, FLJ32827 ENSG00000165309 Armadillo repeat containing 3 10 22928024-23038523 Predicted intracellular proteins Evidence at protein level HPA037823, HPA037824 Enhanced Tissue enhanced Group enriched 12 fallopian tube: 74.2;testis: 61.0 lung: 5.5 Cell line enriched 10 CAPAN-2: 5.3 +OTUD1 DUBA7, OTDC1 ENSG00000165312 OTU deubiquitinase 1 10 23439458-23442390 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038503, HPA038504 Uncertain Approved Nucleoplasm
Nuclear bodies
Golgi apparatus Renal cancer:6.61e-7 (favourable), Endometrial cancer:4.59e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 43.3 Cell line enhanced CAPAN-2: 37.8;HaCaT: 36.0;SiHa: 28.0 +ARHGAP12 FLJ10971, FLJ20737, FLJ21785 ENSG00000165322 Rho GTPase activating protein 12 10 31805404-31928876 Predicted intracellular proteins Evidence at protein level HPA000412 Enhanced Renal cancer:4.64e-5 (favourable), Glioma:1.88e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 45.2 Mixed +FAT3 CDHF15, CDHR10, KIAA1989 ENSG00000165323 FAT atypical cadherin 3 11 92352096-92896470 Predicted membrane proteins Evidence at protein level HPA026878 Uncertain Tissue enriched Tissue enhanced cerebral cortex: 3.9;seminal vesicle: 2.6 prostate: 1.6 Cell line enhanced AF22: 3.6;NTERA-2: 1.2;U-2 OS: 1.1;U-251 MG: 1.8 +DEUP1 CCDC67, FLJ25393 ENSG00000165325 Deuterosome assembly protein 1 11 93329971-93438487 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010986 Uncertain Not detected Group enriched 11 fallopian tube: 7.6;testis: 29.8 thyroid gland: 1.6 Not detected +HECTD2 FLJ37306 ENSG00000165338 HECT domain E3 ubiquitin protein ligase 2 10 91409280-91514829 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037767 Approved Approved Nucleoplasm Renal cancer:1.67e-5 (unfavourable) Mixed Mixed prostate: 28.1 Mixed +SLC7A3 ATRC3, CAT-3, FLJ14541 ENSG00000165349 Solute carrier family 7 member 3 X 70925582-70931125 Predicted membrane proteins, Transporters Evidence at protein level HPA003629 Approved Tissue enriched Tissue enhanced endometrium: 7.8;prostate: 9.9;seminal vesicle: 7.5 smooth muscle: 4.1 Cell line enhanced HAP1: 66.1;NTERA-2: 130.6;REH: 25.9 +FBXO33 Fbx33 ENSG00000165355 F-box protein 33 14 39397669-39432500 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046657 Approved Approved Nucleoplasm Renal cancer:4.58e-4 (favourable), Lung cancer:4.94e-4 (favourable) Expressed in all Expressed in all bone marrow: 33.3 Expressed in all +INTS6L DDX26B, FLJ41215 ENSG00000165359 Integrator complex subunit 6 like X 135520643-135582510 Predicted intracellular proteins Evidence at protein level HPA001552, HPA013200, HPA013335, HPA030747 Uncertain Supported Centrosome
Mitochondria Renal cancer:4.28e-8 (unfavourable), Urothelial cancer:2.94e-4 (favourable), Cervical cancer:5.39e-4 (favourable), Pancreatic cancer:5.54e-4 (favourable) Mixed Mixed lymph node: 14.6 Mixed +GPR101 ENSG00000165370 G protein-coupled receptor 101 X 137030148-137031674 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA001084 Uncertain Not detected Not detected cerebral cortex: 0.1 Not detected +CLDN2 ENSG00000165376 Claudin 2 X 106900164-106930861 Predicted membrane proteins Evidence at protein level CAB002609, HPA051548 Enhanced Supported Nucleoplasm
Cell Junctions Thyroid cancer:1.70e-4 (favourable) Group enriched Tissue enhanced gallbladder: 159.0;kidney: 171.8;seminal vesicle: 129.3 epididymis: 41.1 Group enriched 23 A549: 24.6;CACO-2: 18.2;RPTEC TERT1: 35.1 +LRFN5 C14orf146, FIGLER8, SALM5 ENSG00000165379 Leucine rich repeat and fibronectin type III domain containing 5 14 41607570-41904549 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA001177 Uncertain Mixed Tissue enhanced parathyroid gland: 52.3 cervix, uterine: 16.8 Cell line enhanced AN3-CA: 16.8;RPTEC TERT1: 4.6;SCLC-21H: 11.1;U-138 MG: 11.4 +LRRC18 MGC34773, UNQ933, UNQ9338, VKGE9338 ENSG00000165383 Leucine rich repeat containing 18 10 48909483-48914232 Predicted intracellular proteins Evidence at protein level HPA039256 Enhanced Tissue enhanced Group enriched 8 fallopian tube: 12.1;testis: 25.3 lung: 2.3 Not detected +SPTSSA C14orf147, ssSPTa ENSG00000165389 Serine palmitoyltransferase small subunit A 14 34432789-34462356 Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all adrenal gland: 90.1 Expressed in all +WRN RECQ3, RECQL2 ENSG00000165392 Werner syndrome RecQ like helicase 8 31033801-31173769 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028661 Approved Supported Nuclear speckles Expressed in all Mixed endometrium: 14.8 Expressed in all +MARCH8 c-MIR, CMIR, MARCH-VIII, MIR, RNF178 ENSG00000165406 Membrane associated ring-CH-type finger 8 10 45454585-45594906 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014597 Approved Pancreatic cancer:2.71e-4 (favourable), Renal cancer:6.64e-4 (favourable) Expressed in all Expressed in all testis: 104.6 Expressed in all +TSHR LGR3 ENSG00000165409 Thyroid stimulating hormone receptor 14 80954989-81146302 Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000473 Approved Tissue enriched Tissue enriched 282 thyroid gland: 445.5 lymph node: 1.5 Cell line enhanced MOLT-4: 18.4;SCLC-21H: 25.2;U-266/70: 7.9 +CFL2 NEM7 ENSG00000165410 Cofilin 2 14 34706769-34714823 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037078, HPA045599 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:2.16e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 242.7 Expressed in all +SUGT1 SGT1 ENSG00000165416 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 13 52652709-52700909 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015942, HPA043949 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Head and neck cancer:8.69e-4 (unfavourable) Expressed in all Expressed in all testis: 63.4 Expressed in all +GTF2A1 TFIIA ENSG00000165417 General transcription factor IIA subunit 1 14 81175452-81221377 Predicted intracellular proteins Evidence at protein level HPA000869 Uncertain Supported Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 38.9 Expressed in all +ZCCHC24 C10orf56, FLJ90798, Z3CXXC8 ENSG00000165424 Zinc finger CCHC-type containing 24 10 79382325-79445627 Predicted intracellular proteins Evidence at protein level HPA038348 Approved Approved Nucleoplasm
Mitochondria Renal cancer:5.35e-6 (unfavourable), Ovarian cancer:3.76e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 70.6 Cell line enhanced ASC diff: 92.6;ASC TERT1: 80.6;BJ hTERT+: 74.4;HSkMC: 87.6 +PGM2L1 BM32A, FLJ32029 ENSG00000165434 Phosphoglucomutase 2 like 1 11 74330318-74398473 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056995, HPA060948 Enhanced Approved Mitochondria Mixed Tissue enriched 9 cerebral cortex: 64.1 endometrium: 7.3 Cell line enhanced RH-30: 18.2 +PHYHIPL Em:AC025038.1, KIAA1796 ENSG00000165443 Phytanoyl-CoA 2-hydroxylase interacting protein like 10 59176590-59247774 Predicted intracellular proteins Evidence at protein level HPA038746 Uncertain Approved Cytosol Renal cancer:1.60e-7 (favourable) Group enriched Tissue enhanced cerebral cortex: 89.4 adrenal gland: 22.4 Cell line enhanced Hep G2: 22.4;SCLC-21H: 6.7;SH-SY5Y: 20.0;SK-BR-3: 6.0 +SLC16A9 C10orf36, FLJ43803, MCT9 ENSG00000165449 Solute carrier family 16 member 9 10 59650761-59736002 Predicted membrane proteins, Transporters Evidence at protein level HPA049286 Approved Approved Nucleus
Cell Junctions Renal cancer:2.56e-6 (favourable) Mixed Tissue enhanced adrenal gland: 198.5;kidney: 201.0 spleen: 56.3 Cell line enhanced HAP1: 11.1;NTERA-2: 20.0;U-937: 14.6 +FOLR2 ENSG00000165457 Folate receptor beta 11 72216601-72221950 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Thyroid cancer:8.41e-4 (favourable), Colorectal cancer:8.42e-4 (unfavourable) Expressed in all Expressed in all placenta: 235.4 Group enriched 6 Daudi: 2.6;U-698: 12.5 +INPPL1 SHIP2 ENSG00000165458 Inositol polyphosphate phosphatase like 1 11 72223701-72239105 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037601 Approved Supported Golgi apparatus
Cytosol Liver cancer:7.37e-4 (unfavourable) Expressed in all Expressed in all spleen: 64.3 Expressed in all +PHOX2A ARIX, CFEOM2, FEOM2, PMX2A ENSG00000165462 Paired like homeobox 2a 11 72239077-72245664 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA065621, HPA078004 Enhanced Approved Nucleus
Nuclear membrane
Vesicles Tissue enriched Tissue enriched 14 adrenal gland: 26.4 appendix: 1.8 Cell line enriched 240 SH-SY5Y: 603.9 +MBL2 COLEC1, MBL ENSG00000165471 Mannose binding lectin 2 10 52765380-52771700 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002027, CAB016782 Enhanced Tissue enriched Tissue enriched 1414 liver: 141.4 all non-specific tissues: 0.0 Cell line enriched 9 Hep G2: 1.5 +GJB2 CX26, DFNA3, DFNB1, NSRD1 ENSG00000165474 Gap junction protein beta 2 13 20187470-20192898 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB013093, HPA014362 Uncertain Approved Mitochondria Renal cancer:2.53e-6 (unfavourable), Pancreatic cancer:2.90e-4 (unfavourable), Glioma:5.98e-4 (unfavourable), Lung cancer:6.25e-4 (unfavourable) Expressed in all Tissue enriched 9 esophagus: 725.5 tonsil: 81.3 Cell line enhanced CAPAN-2: 129.4;hTCEpi: 78.0;RT4: 137.8 +CRYL1 GDH, lambda-CRY, MGC149525, MGC149526 ENSG00000165475 Crystallin lambda 1 13 20403667-20525857 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040403 Enhanced Approved Nucleus
Nucleoli
Golgi apparatus
Plasma membrane Renal cancer:2.30e-9 (favourable), Endometrial cancer:1.76e-5 (favourable) Expressed in all Expressed in all kidney: 338.1 Mixed +REEP3 C10orf74, Yip2b ENSG00000165476 Receptor accessory protein 3 10 63521363-63625123 Predicted membrane proteins Evidence at protein level Pancreatic cancer:1.32e-4 (unfavourable), Liver cancer:3.19e-4 (unfavourable), Head and neck cancer:7.83e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 56.9 Mixed +HEPACAM FLJ25530, GLIALCAM, hepaCAM ENSG00000165478 Hepatic and glial cell adhesion molecule 11 124919193-124936412 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA017613, CAB025486 Enhanced Approved Vesicles Tissue enriched Tissue enriched 5 cerebral cortex: 80.7 adipose tissue: 15.1 Cell line enriched 27 Hep G2: 18.8 +SKA3 C13orf3, MGC4832, RAMA1 ENSG00000165480 Spindle and kinetochore associated complex subunit 3 13 21153595-21176602 Predicted intracellular proteins Evidence at protein level HPA039272 Approved Uncertain Plasma membrane
Cytosol Liver cancer:9.73e-6 (unfavourable), Pancreatic cancer:3.77e-4 (unfavourable), Melanoma:8.71e-4 (unfavourable) Mixed Tissue enhanced testis: 10.1 lymph node: 5.0 Mixed +MICU2 EFHA1 ENSG00000165487 Mitochondrial calcium uptake 2 13 21492691-21604214 Predicted intracellular proteins, Transporters Evidence at protein level HPA045511, HPA058790 Approved Approved Nucleus
Mitochondria Renal cancer:1.40e-7 (favourable) Expressed in all Expressed in all kidney: 78.5 Expressed in all +DDIAS C11orf82, FLJ25416, FLJ38838, noxin ENSG00000165490 DNA damage induced apoptosis suppressor 11 82899975-82958277 Predicted secreted proteins Evidence at protein level HPA038540, HPA038541 Approved Approved Plasma membrane
Cytosol Mixed Tissue enhanced testis: 20.0 skeletal muscle: 6.4 Mixed +PCF11 KIAA0824 ENSG00000165494 PCF11 cleavage and polyadenylation factor subunit 11 83156988-83187451 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040779 Supported Nucleoplasm
Mitochondria Urothelial cancer:2.03e-5 (favourable), Head and neck cancer:1.34e-4 (favourable) Expressed in all Expressed in all testis: 44.8 Expressed in all +PKNOX2 ENSG00000165495 PBX/knotted 1 homeobox 2 11 125164687-125433389 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028867, CAB034342, HPA055368, HPA066962 Supported Enhanced Nucleus
Cytokinetic bridge Tissue enhanced Mixed thyroid gland: 20.1 Cell line enhanced AF22: 38.2;AN3-CA: 9.0;LHCN-M2: 9.6;WM-115: 21.0 +RPL10L ENSG00000165496 Ribosomal protein L10 like 14 46651010-46651821 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA011311 Uncertain Approved Endoplasmic reticulum
Cytosol Tissue enriched Tissue enriched 45 testis: 127.0 rectum: 2.8 Cell line enriched 54 U-2 OS: 40.6 +LRR1 LRR-1, MGC20689, PPIL5 ENSG00000165501 Leucine rich repeat protein 1 14 49598697-49614672 Predicted intracellular proteins Evidence at protein level HPA065703, HPA069364 Approved Approved Nucleoplasm
Nuclear membrane
Vesicles Renal cancer:4.90e-7 (unfavourable), Liver cancer:2.97e-4 (unfavourable) Expressed in all Tissue enhanced testis: 33.6 lymph node: 12.1 Expressed in all +RPL36AL RPL36A ENSG00000165502 Ribosomal protein L36a like 14 49618519-49620685 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA077586 Approved Endoplasmic reticulum
Plasma membrane
Cytosol Thyroid cancer:2.83e-4 (favourable) Expressed in all Expressed in all ovary: 529.4 Expressed in all +DNAAF2 C14orf104, CILD10, FLJ10563, KTU, PF13 ENSG00000165506 Dynein axonemal assembly factor 2 14 49625174-49635230 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA002894, HPA004113 Enhanced Supported Cytosol Renal cancer:6.74e-7 (favourable) Expressed in all Expressed in all fallopian tube: 13.9 Expressed in all +C10orf10 DEPP, FIG, Fseg ENSG00000165507 Chromosome 10 open reading frame 10 10 44970981-44978810 Predicted secreted proteins Evidence at protein level CAB013687, HPA037819 Uncertain Approved Nucleus
Vesicles Renal cancer:2.29e-6 (unfavourable) Expressed in all Expressed in all adipose tissue: 238.0 Cell line enhanced ASC diff: 98.2;HDLM-2: 98.9;HHSteC: 216.9;HSkMC: 146.6;HUVEC TERT2: 137.8 +MAGEC3 CT7.2, HCA2, MAGE-C3 ENSG00000165509 MAGE family member C3 X 141838316-141897832 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA052067 Approved Tissue enriched Tissue enhanced testis: 1.0 cerebral cortex: 0.6 Cell line enhanced U-266/84: 1.5 +ZNF22 HKR-T1, KOX15, Zfp422, ZNF422 ENSG00000165512 Zinc finger protein 22 10 45000475-45005326 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016736, HPA054893 Approved Enhanced Nucleus Renal cancer:1.11e-5 (unfavourable), Stomach cancer:8.06e-4 (unfavourable) Expressed in all Expressed in all placenta: 46.7 Mixed +KLHDC2 HCLP-1, LCP ENSG00000165516 Kelch domain containing 2 14 49767608-49786385 Predicted intracellular proteins Evidence at protein level HPA000628 Approved Supported Nucleoplasm
Nuclear membrane
Nuclear bodies Renal cancer:2.75e-10 (favourable) Expressed in all Expressed in all thyroid gland: 47.1 Expressed in all +EML5 EMAP-2, HuEMAP-2 ENSG00000165521 Echinoderm microtubule associated protein like 5 14 88612431-88792752 Predicted intracellular proteins Evidence at protein level HPA054019, HPA055379 Uncertain Not detected Tissue enhanced ovary: 23.7 prostate: 8.7 Cell line enhanced SH-SY5Y: 26.6 +NEMF FLJ10051, NY-CO-1, SDCCAG1 ENSG00000165525 Nuclear export mediator factor 14 49782083-49853203 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004160 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:2.85e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 46.3 Expressed in all +RPUSD4 FLJ14494 ENSG00000165526 RNA pseudouridylate synthase domain containing 4 11 126202094-126211692 Predicted intracellular proteins Evidence at protein level HPA039689 Approved Approved Nucleoplasm
Mitochondria Liver cancer:1.24e-4 (unfavourable), Colorectal cancer:6.14e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 44.9 Expressed in all +ARF6 ENSG00000165527 ADP ribosylation factor 6 14 49893092-49897054 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002778 Approved Pancreatic cancer:3.10e-5 (unfavourable) Expressed in all Expressed in all esophagus: 96.6 Expressed in all +TTC8 BBS8, RP51 ENSG00000165533 Tetratricopeptide repeat domain 8 14 88824153-88881078 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Endometrial cancer:1.69e-5 (favourable), Renal cancer:4.89e-4 (favourable), Ovarian cancer:7.77e-4 (favourable) Expressed in all Expressed in all ovary: 91.0 Expressed in all +TMEM63C C14orf171, CSC1, DKFZp434P0111, hsCSC1 ENSG00000165548 Transmembrane protein 63C 14 77116568-77259495 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA030657 Uncertain Approved Centrosome Mixed Tissue enhanced adrenal gland: 12.9;cerebral cortex: 18.5;testis: 13.8 epididymis: 5.6 Cell line enhanced Daudi: 13.3;Karpas-707: 17.4;SCLC-21H: 38.5;SK-BR-3: 21.9 +NGB ENSG00000165553 Neuroglobin 14 77265483-77271312 Predicted intracellular proteins, Transporters Evidence at protein level HPA042615, HPA058596 Enhanced Tissue enhanced Group enriched 5 adrenal gland: 10.1;cerebral cortex: 4.8;fallopian tube: 2.2 pancreas: 1.0 Group enriched 30 RPMI-8226: 4.3;SCLC-21H: 14.4 +NOXRED1 C14orf148, FLJ32809 ENSG00000165555 NADP dependent oxidoreductase domain containing 1 14 77394021-77423517 Predicted intracellular proteins Evidence at transcript level HPA055658 Approved Mixed Tissue enriched 7 testis: 11.7 thyroid gland: 1.6 Not detected +CDX2 CDX3 ENSG00000165556 Caudal type homeobox 2 13 27962137-27971139 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002221, HPA045669, HPA049580 Enhanced Supported Nucleoplasm Tissue enriched Group enriched 6 colon: 30.8;duodenum: 22.3;rectum: 24.9;small intestine: 30.2 appendix: 4.7 Cell line enhanced CACO-2: 9.4;CAPAN-2: 3.3;HEK 293: 5.6 +AMER2 FAM123A, FLJ25477 ENSG00000165566 APC membrane recruitment protein 2 13 25161684-25172288 Predicted intracellular proteins Evidence at protein level HPA039458 Enhanced Tissue enriched Tissue enriched 53 cerebral cortex: 72.4 fallopian tube,testis: 1.3 Group enriched 5 AF22: 3.6;SCLC-21H: 3.5;U-266/70: 5.2 +AKR1E2 AKR1CL2, AKRDC1, MGC10612 ENSG00000165568 Aldo-keto reductase family 1 member E2 10 4786629-4848062 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037821, HPA037822 Enhanced Enhanced Nucleoplasm
Golgi apparatus Mixed Tissue enriched 5 testis: 29.8 thyroid gland: 5.6 Cell line enhanced U-2197: 19.2 +KBTBD6 DKFZp547E1912 ENSG00000165572 Kelch repeat and BTB domain containing 6 13 41127569-41132746 Predicted intracellular proteins Evidence at protein level HPA046861, HPA048914 Uncertain Expressed in all Mixed cerebral cortex: 23.6 Expressed in all +SSX5 ENSG00000165583 SSX family member 5 X 48186220-48196763 Predicted intracellular proteins Evidence at protein level HPA045683 Uncertain Approved Nucleus
Nucleoli Not detected Tissue enhanced thyroid gland: 1.0 testis: 0.9 Cell line enriched 6 BEWO: 4.8 +SSX3 CT5.3 ENSG00000165584 SSX family member 3 X 48346428-48356707 Predicted intracellular proteins Evidence at protein level HPA045683 Approved Approved Nucleus
Nucleoli Not detected Tissue enriched 70 testis: 25.3 thyroid gland: 0.3 Cell line enhanced Karpas-707: 1.5 +OTX2 ENSG00000165588 Orthodenticle homeobox 2 14 56799905-56810479 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000633 Approved Tissue enriched Not detected testis: 0.5 Group enriched 735 HAP1: 239.3;NTERA-2: 192.9 +FAAH2 AMDD, FAAH-2, FLJ31204, RP11-479E16.1 ENSG00000165591 Fatty acid amide hydrolase 2 X 57286706-57489196 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:2.47e-13 (favourable), Urothelial cancer:6.83e-5 (favourable), Thyroid cancer:2.66e-4 (favourable), Ovarian cancer:5.99e-4 (favourable) Mixed Mixed parathyroid gland: 20.2 Cell line enhanced CAPAN-2: 12.2;HDLM-2: 12.0;RPMI-8226: 18.0;U-266/70: 15.9 +DRGX DRG11, PRRXL1 ENSG00000165606 Dorsal root ganglia homeobox 10 49364181-49396016 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA043978 Uncertain Approved Nucleus
Nucleoli
Cytosol Mixed Tissue enriched 11 adrenal gland: 8.9 skin: 0.8 Group enriched 16 RH-30: 13.8;SH-SY5Y: 68.3;U-2197: 21.7 +NUDT5 hYSAH1, YSA1H ENSG00000165609 Nudix hydrolase 5 10 12165325-12196144 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019827 Approved Approved Nucleus
Vesicles
Centrosome Renal cancer:7.14e-12 (unfavourable) Expressed in all Expressed in all thyroid gland: 45.6 Expressed in all +DACT1 DAPPER, DAPPER1, FRODO, HDPR1, THYEX3 ENSG00000165617 Dishevelled binding antagonist of beta catenin 1 14 58633967-58648321 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003016 Uncertain Supported Nucleoplasm Expressed in all Mixed gallbladder: 40.2 Cell line enhanced U-138 MG: 31.7 +OXGR1 aKGR, GPR80, GPR99, P2RY15, P2Y15 ENSG00000165621 Oxoglutarate receptor 1 13 96985719-96994730 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA067673 Supported Plasma membrane Mixed Tissue enhanced breast: 5.1 kidney: 4.6 Cell line enhanced RT4: 2.6;SK-BR-3: 1.1;U-2 OS: 1.7 +UCMA C10orf49 ENSG00000165623 Upper zone of growth plate and cartilage matrix associated 10 13221767-13234334 Predicted secreted proteins Evidence at transcript level HPA046718 Uncertain Tissue enhanced Tissue enhanced ovary: 1.4 heart muscle: 0.4 Not detected +BEND7 C10orf30, FLJ40283 ENSG00000165626 BEN domain containing 7 10 13438484-13528974 Predicted intracellular proteins Evidence at protein level HPA037835 Uncertain Approved Nucleus
Nucleoli fibrillar center
Vesicles Mixed Mixed thyroid gland: 40.9 Mixed +ATP5C1 ATP5C, ATP5CL1 ENSG00000165629 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 10 7788129-7807815 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060949 Approved Renal cancer:9.26e-4 (favourable) Expressed in all Expressed in all heart muscle: 463.5 Expressed in all +PRPF18 hPrp18 ENSG00000165630 Pre-mRNA processing factor 18 10 13586927-13630868 Predicted intracellular proteins Evidence at protein level HPA037599, HPA047950 Supported Approved Nuclear speckles
Cytosol Liver cancer:1.06e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 38.5 Expressed in all +TAF3 TAF140, TAFII140 ENSG00000165632 TATA-box binding protein associated factor 3 10 7818504-8016627 Predicted intracellular proteins Evidence at protein level HPA066184 Supported Nucleoplasm
Nuclear membrane Liver cancer:2.14e-7 (unfavourable), Renal cancer:5.01e-4 (unfavourable) Expressed in all Mixed testis: 14.1 Expressed in all +VSTM4 C10orf72, FLJ31737 ENSG00000165633 V-set and transmembrane domain containing 4 10 49014245-49115509 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA017279 Uncertain Approved Nucleus
Vesicles Urothelial cancer:4.25e-4 (unfavourable) Tissue enriched Mixed adrenal gland: 54.8 Cell line enhanced RH-30: 9.1;U-138 MG: 10.5;U-2197: 22.4;U-87 MG: 11.4 +VDAC2 ENSG00000165637 Voltage dependent anion channel 2 10 75210154-75231448 Predicted intracellular proteins, Transporters Evidence at protein level HPA043475 Enhanced Enhanced Mitochondria Head and neck cancer:4.51e-4 (unfavourable), Liver cancer:4.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 269.4 Expressed in all +SOHLH1 bA100C15.3, bHLHe80, C9orf157, NOHLH, SPATA27, TEB2 ENSG00000165643 Spermatogenesis and oogenesis specific basic helix-loop-helix 1 9 135693407-135699528 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059439 Approved Nuclear speckles Mixed Group enriched 27 cerebral cortex: 6.3;testis: 13.4 skin: 0.3 Group enriched 36 CACO-2: 14.6;U-266/84: 19.8 +COMTD1 FLJ23841 ENSG00000165644 Catechol-O-methyltransferase domain containing 1 10 75233969-75236030 Predicted intracellular proteins Evidence at protein level HPA042165 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Renal cancer:1.88e-4 (favourable) Expressed in all Mixed duodenum: 13.6 Cell line enhanced HEK 293: 43.6;PC-3: 61.2 +SLC18A2 SVAT, SVMT, VMAT2 ENSG00000165646 Solute carrier family 18 member A2 10 117241093-117279430 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA073224 Approved Mixed Tissue enhanced cervix, uterine: 47.6 adrenal gland: 19.0 Cell line enriched 18 HMC-1: 308.7 +PDZD8 bA129M16.2, FLJ34427, PDZK8 ENSG00000165650 PDZ domain containing 8 10 117277274-117375467 Predicted secreted proteins Evidence at protein level HPA015716, HPA051610 Uncertain Approved Nucleoli fibrillar center
Plasma membrane Pancreatic cancer:6.10e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 46.5 Expressed in all +ZNF503 FLJ45745, MGC2555, Nlz2 ENSG00000165655 Zinc finger protein 503 10 75397830-75401906 Predicted intracellular proteins Evidence at protein level HPA026848 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.97e-4 (favourable), Prostate cancer:3.50e-4 (unfavourable) Expressed in all Mixed adrenal gland: 25.7 Cell line enhanced HEK 293: 100.8;PC-3: 132.2 +FAM175B ABRO1, Em:AC068896.4, KIAA0157 ENSG00000165660 Family with sequence similarity 175 member B 10 124801785-124836670 Predicted intracellular proteins Evidence at protein level HPA037591, HPA037592, HPA074089 Approved Supported Cytosol Expressed in all Expressed in all thyroid gland: 21.0 Expressed in all +QSOX2 DKFZp762A2013, QSCN6L1, SOXN ENSG00000165661 Quiescin sulfhydryl oxidase 2 9 136206333-136245841 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012716, HPA017280 Uncertain Enhanced Nucleoplasm
Golgi apparatus Renal cancer:9.64e-6 (unfavourable) Expressed in all Expressed in all lymph node: 20.7 Expressed in all +FAM204A bA319I23.1, C10orf84, FLJ13188 ENSG00000165669 Family with sequence similarity 204 member A 10 118297930-118342328 Predicted intracellular proteins Evidence at protein level HPA038182, HPA062025 Approved Supported Nucleus
Nucleoli Renal cancer:8.59e-4 (unfavourable) Expressed in all Expressed in all testis: 89.3 Expressed in all +NSD1 ARA267, FLJ22263, KMT3B, STO ENSG00000165671 Nuclear receptor binding SET domain protein 1 5 177133025-177300215 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048431, HPA070333, HPA073705 Supported Supported Nucleus
Plasma membrane Expressed in all Expressed in all testis: 43.2 Mixed +PRDX3 AOP-1, AOP1, MER5, SP-22 ENSG00000165672 Peroxiredoxin 3 10 119167703-119178833 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008656, HPA041488 Enhanced Expressed in all Expressed in all adrenal gland: 429.1 Expressed in all +ENOX2 APK1, COVA1, tNOX ENSG00000165675 Ecto-NOX disulfide-thiol exchanger 2 X 130623369-130903317 Predicted intracellular proteins Evidence at protein level HPA000514 Uncertain Approved Nucleus
Actin filaments Renal cancer:1.09e-5 (favourable) Expressed in all Expressed in all endometrium: 20.0 Expressed in all +GHITM DERP2, HSPC282, My021, PTD010, TMBIM5 ENSG00000165678 Growth hormone inducible transmembrane protein 10 84139440-84153245 Predicted membrane proteins Evidence at protein level HPA016464, HPA061664 Approved Supported Mitochondria Renal cancer:2.32e-10 (favourable), Head and neck cancer:1.76e-4 (unfavourable) Expressed in all Expressed in all kidney: 352.9 Expressed in all +CLEC1B CLEC2 ENSG00000165682 C-type lectin domain family 1 member B 12 9985642-10013424 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 6 liver: 33.7 bone marrow: 5.6 Group enriched 5 Karpas-707: 8.1;U-266/84: 19.9 +SNAPC4 FLJ13451, PTFalpha, SNAP190 ENSG00000165684 Small nuclear RNA activating complex polypeptide 4 9 136375577-136400168 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046627, HPA073243 Uncertain Approved Nucleoplasm
Nuclear membrane Pancreatic cancer:4.52e-5 (favourable) Expressed in all Expressed in all testis: 20.6 Expressed in all +TMEM52B C12orf59, FLJ31166 ENSG00000165685 Transmembrane protein 52B 12 10170542-10191801 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA058096 Enhanced Approved Focal adhesion sites Tissue enriched Tissue enriched 21 kidney: 183.5 placenta: 8.6 Cell line enriched 8 CACO-2: 79.4 +PMPCA Alpha-MPP, INPP5E, KIAA0123 ENSG00000165688 Peptidase, mitochondrial processing alpha subunit 9 136410570-136423761 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021648, HPA063735 Enhanced Enhanced Mitochondria Renal cancer:2.14e-6 (favourable), Pancreatic cancer:8.00e-5 (favourable) Expressed in all Expressed in all adrenal gland: 38.6 Expressed in all +SDCCAG3 NY-CO-3 ENSG00000165689 Serologically defined colon cancer antigen 3 9 136401922-136410609 Predicted intracellular proteins Evidence at protein level HPA029303 Approved Renal cancer:8.50e-5 (unfavourable) Expressed in all Expressed in all testis: 36.4 Expressed in all +FRMD7 FLJ43346, NYS, NYS1 ENSG00000165694 FERM domain containing 7 X 132076993-132128020 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000886 Uncertain Not detected Tissue enhanced endometrium: 2.8;kidney: 3.0;smooth muscle: 3.5 seminal vesicle: 0.7 Cell line enhanced U-87 MG: 1.5 +AK8 C9orf98, FLJ32704 ENSG00000165695 Adenylate kinase 8 9 132725578-132878777 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021443, HPA021445, HPA023894 Enhanced Renal cancer:1.61e-4 (favourable) Mixed Tissue enhanced epididymis: 16.0;fallopian tube: 30.0;testis: 21.7 thyroid gland: 5.8 Cell line enhanced MCF7: 1.8;RPTEC TERT1: 2.0;T-47d: 1.6 +SPACA9 C9orf9, Mast ENSG00000165698 Sperm acrosome associated 9 9 132878027-132890201 Predicted intracellular proteins Evidence at protein level HPA022243, HPA051600 Enhanced Approved Mitochondria Renal cancer:8.31e-4 (favourable), Endometrial cancer:8.61e-4 (favourable) Expressed in all Group enriched 5 epididymis: 90.3;fallopian tube: 63.1;testis: 130.1 thyroid gland: 18.0 Mixed +TSC1 hamartin, KIAA0243, LAM, TSC ENSG00000165699 Tuberous sclerosis 1 9 132891348-132944633 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011568, CAB012481, HPA074132 Supported Enhanced Cytosol Liver cancer:6.03e-6 (unfavourable), Renal cancer:7.91e-4 (favourable), Pancreatic cancer:8.01e-4 (favourable) Expressed in all Expressed in all testis: 33.7 Expressed in all +GFI1B ZNF163B ENSG00000165702 Growth factor independent 1B transcriptional repressor 9 132944000-132991687 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004420 Enhanced Not detected Tissue enriched 15 bone marrow: 23.8 testis: 1.5 Group enriched 6 HEL: 151.4;HMC-1: 92.4;K-562: 47.5 +HPRT1 HGPRT, HPRT ENSG00000165704 Hypoxanthine phosphoribosyltransferase 1 X 134460153-134520513 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006360, CAB012200 Enhanced Supported Cytosol Head and neck cancer:1.35e-5 (unfavourable) Expressed in all Expressed in all testis: 139.1 Mixed +BORCS5 LOH12CR1, LOH1CR12 ENSG00000165714 BLOC-1 related complex subunit 5 12 12357079-12469694 Predicted intracellular proteins Evidence at protein level HPA039509, HPA043627 Approved Supported Cytosol Liver cancer:3.47e-4 (unfavourable) Expressed in all Mixed cerebral cortex,epididymis: 7.4 Expressed in all +FAM69B C9orf136, MGC20262 ENSG00000165716 Family with sequence similarity 69 member B 9 136712570-136724050 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046812, HPA054443 Uncertain Approved Nucleus
Nuclear bodies
Vesicles Colorectal cancer:1.77e-5 (unfavourable), Pancreatic cancer:9.48e-5 (favourable) Expressed in all Mixed placenta: 29.6 Cell line enhanced EFO-21: 67.2;HEK 293: 59.7;HUVEC TERT2: 67.6 +ZMYND19 MIZIP ENSG00000165724 Zinc finger MYND-type containing 19 9 137582079-137590490 Predicted intracellular proteins Evidence at protein level HPA020642, HPA050761 Supported Approved Golgi apparatus
Vesicles Liver cancer:1.70e-4 (unfavourable) Expressed in all Expressed in all testis: 46.1 Expressed in all +STOX1 C10orf24, FLJ25162 ENSG00000165730 Storkhead box 1 10 68827541-68895432 Disease related genes, Predicted secreted proteins Evidence at protein level HPA037844, HPA037845 Approved Supported Nucleoplasm
Nucleoli fibrillar center
Cytosol Breast cancer:3.37e-5 (favourable), Lung cancer:2.08e-4 (favourable) Mixed Tissue enhanced fallopian tube: 20.0 cerebral cortex: 14.0 Cell line enhanced AN3-CA: 8.0;HAP1: 8.3 +RET CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 ENSG00000165731 Ret proto-oncogene 10 43077027-43130351 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002581, HPA008356, HPA008495, CAB018342 Approved Supported Supported Vesicles
Plasma membrane
Cytosol Endometrial cancer:5.02e-4 (unfavourable) Tissue enhanced Tissue enriched 5 parathyroid gland: 154.5 adrenal gland: 29.8 Cell line enriched 5 SH-SY5Y: 404.3 +DDX21 GURDB, RH-II/GU ENSG00000165732 DExD-box helicase 21 10 68956128-68985073 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036592, HPA036593 Enhanced Enhanced Nucleus
Nucleoli Pancreatic cancer:3.12e-4 (unfavourable) Expressed in all Expressed in all appendix: 71.2 Expressed in all +BMS1 BMS1L, KIAA0187 ENSG00000165733 BMS1, ribosome biogenesis factor 10 42782801-42834937 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036589, HPA043081 Uncertain Enhanced Nucleus
Nucleoli Liver cancer:1.06e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 20.3 Expressed in all +STK32C MGC23665, PKE, YANK3 ENSG00000165752 Serine/threonine kinase 32C 10 132207492-132331847 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017894 Uncertain Liver cancer:1.68e-6 (unfavourable), Renal cancer:5.31e-6 (unfavourable), Endometrial cancer:1.09e-4 (unfavourable) Expressed in all Expressed in all testis: 52.6 Expressed in all +KIAA1462 JCAD ENSG00000165757 KIAA1462 10 30012800-30115494 Predicted intracellular proteins Evidence at protein level HPA017956 Enhanced Supported Vesicles
Cell Junctions Stomach cancer:2.01e-4 (unfavourable), Renal cancer:2.54e-4 (unfavourable) Expressed in all Mixed placenta: 48.7 Cell line enhanced HUVEC TERT2: 25.1;TIME: 55.5 +OR4K2 ENSG00000165762 Olfactory receptor family 4 subfamily K member 2 14 19876232-19877309 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +FUNDC2 DC44, HCBP6 ENSG00000165775 FUN14 domain containing 2 X 155025980-155060303 Predicted intracellular proteins Evidence at protein level HPA059129 Approved Liver cancer:3.78e-5 (unfavourable), Endometrial cancer:7.26e-4 (unfavourable), Cervical cancer:9.20e-4 (favourable) Expressed in all Expressed in all ovary: 7.8 Expressed in all +TMEM55B C14orf9, MGC26684 ENSG00000165782 Transmembrane protein 55B 14 20457719-20461612 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048528 Approved Renal cancer:1.01e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 42.0 Expressed in all +METTL17 FLJ20859, METT11D1 ENSG00000165792 Methyltransferase like 17 14 20989770-20997035 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002955, HPA059802 Uncertain Enhanced Nucleus Expressed in all Expressed in all adrenal gland: 23.7 Expressed in all +SLC39A2 ZIP2 ENSG00000165794 Solute carrier family 39 member 2 14 20999255-21001871 Predicted membrane proteins Evidence at protein level HPA030489 Uncertain Mixed Group enriched 11 esophagus: 19.0;prostate: 19.2;seminal vesicle: 46.9;skin: 34.1 breast: 2.6 Cell line enriched 67 HaCaT: 20.5 +NDRG2 KIAA1248, SYLD ENSG00000165795 NDRG family member 2 14 21016763-21070872 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002896, HPA003590, CAB017491 Enhanced Approved Nucleoplasm
Microtubule organizing center
Cytosol Renal cancer:1.43e-12 (favourable), Liver cancer:6.71e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1029.5 Cell line enhanced Hep G2: 38.7 +RNASE7 RAE1 ENSG00000165799 Ribonuclease A family member 7 14 21042226-21044234 Predicted secreted proteins Evidence at protein level HPA005690, CAB062560, CAB068225 Enhanced Tissue enhanced Tissue enhanced esophagus: 72.0;skin: 29.2;tonsil: 19.6 gallbladder: 11.1 Cell line enhanced HBEC3-KT: 17.9;hTCEpi: 7.6;hTERT-HME1: 40.4 +ARHGEF40 FLJ10357, solo ENSG00000165801 Rho guanine nucleotide exchange factor 40 14 21070270-21090240 Predicted intracellular proteins Evidence at protein level HPA030746, HPA030757 Uncertain Expressed in all Expressed in all adrenal gland: 32.5 Mixed +NSMF NELF ENSG00000165802 NMDA receptor synaptonuclear signaling and neuronal migration factor 9 137447570-137459334 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044316 Enhanced Supported Nucleoplasm Renal cancer:1.85e-6 (favourable) Expressed in all Tissue enriched 5 cerebral cortex: 189.6 duodenum: 36.2 Mixed +ZNF219 ENSG00000165804 Zinc finger protein 219 14 21090046-21104722 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030761, HPA056168 Approved Supported Nucleus Expressed in all Expressed in all skin: 44.0 Expressed in all +C12orf50 FLJ35821 ENSG00000165805 Chromosome 12 open reading frame 50 12 87980035-88034037 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 880 testis: 87.9 all non-specific tissues: 0.0 Not detected +CASP7 CMH-1, ICE-LAP3, MCH3 ENSG00000165806 Caspase 7 10 113679162-113730907 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB025563 Approved Breast cancer:2.11e-4 (favourable), Renal cancer:5.90e-4 (unfavourable) Expressed in all Expressed in all small intestine: 74.4 Mixed +PPP1R36 C14orf50 ENSG00000165807 Protein phosphatase 1 regulatory subunit 36 14 64549902-64589380 Predicted intracellular proteins Evidence at protein level HPA077492 Enhanced Mixed Group enriched 6 fallopian tube: 17.4;testis: 58.9 duodenum: 6.6 Group enriched 6 CAPAN-2: 12.6;SCLC-21H: 3.4 +BTNL9 BTN8, FLJ32535 ENSG00000165810 Butyrophilin like 9 5 181040225-181061523 Predicted membrane proteins Evidence at protein level HPA043429 Approved Nuclear membrane
Vesicles Liver cancer:1.55e-9 (favourable), Endometrial cancer:7.51e-4 (unfavourable) Mixed Tissue enhanced adipose tissue: 166.9 lung: 55.8 Cell line enhanced U-2 OS: 5.7;U-698: 25.5 +CCDC186 C10orf118, FLJ10188, FLJ35301 ENSG00000165813 Coiled-coil domain containing 186 10 114120862-114174220 Predicted intracellular proteins Evidence at protein level HPA014569, HPA018019 Approved Approved Golgi apparatus Renal cancer:7.65e-8 (favourable) Expressed in all Expressed in all testis: 32.3 Mixed +VWA2 AMACO, CCSP-2, FLJ16213, FLJ45857, NET42 ENSG00000165816 Von Willebrand factor A domain containing 2 10 114239330-114291513 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037847 Uncertain Mixed Tissue enhanced fallopian tube: 11.0 stomach: 7.8 Group enriched 6 CAPAN-2: 5.9;HaCaT: 2.7;SCLC-21H: 2.1 +METTL3 M6A, MT-A70, Spo8 ENSG00000165819 Methyltransferase like 3 14 21498133-21511375 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:2.19e-5 (unfavourable), Pancreatic cancer:2.72e-4 (favourable), Ovarian cancer:2.78e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 35.5 Expressed in all +SALL2 Hsal2, KIAA0360, ZNF795 ENSG00000165821 Spalt like transcription factor 2 14 21521081-21537216 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004162 Approved Approved Nucleus
Vesicles Pancreatic cancer:1.23e-4 (favourable), Endometrial cancer:3.97e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 67.9 cerebral cortex: 42.4 Cell line enhanced AF22: 123.9;NTERA-2: 95.1;SCLC-21H: 50.0 +PRAP1 UPA ENSG00000165828 Proline rich acidic protein 1 10 133347146-133352683 Predicted secreted proteins Evidence at protein level HPA038713, HPA052451 Supported Uncertain Nucleoplasm
Vesicles
Plasma membrane Group enriched Group enriched 6 duodenum: 928.6;liver: 297.4;small intestine: 1097.7 kidney: 125.6 Group enriched 5 CACO-2: 18.2;Hep G2: 64.2 +TRUB1 PUS4 ENSG00000165832 TruB pseudouridine synthase family member 1 10 114938193-114977676 Predicted intracellular proteins Evidence at protein level HPA037914, HPA057552 Approved Supported Vesicles
Actin filaments Expressed in all Expressed in all adrenal gland: 38.5 Expressed in all +ERICH6B FAM194B, FLJ32682 ENSG00000165837 Glutamate rich 6B 13 45534522-45615739 Predicted intracellular proteins Evidence at transcript level HPA043559 Uncertain Not detected Tissue enriched 35 testis: 3.4 all non-specific tissues: 0.0 Not detected +CYP2C19 CPCJ, CYP2C, P450IIC19 ENSG00000165841 Cytochrome P450 family 2 subfamily C member 19 10 94762624-94853260 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA015066 Supported Not detected Tissue enhanced duodenum: 48.3;liver: 125.6 small intestine: 20.7 Not detected +ZFYVE1 DFCP1, KIAA1589, PPP1R172, TAFF1, ZNFN2A1 ENSG00000165861 Zinc finger FYVE-type containing 1 14 72969451-73027212 Predicted intracellular proteins Evidence at protein level HPA002898 Approved Supported Endoplasmic reticulum Renal cancer:5.07e-12 (favourable) Expressed in all Expressed in all testis: 22.6 Expressed in all +C10orf82 Em:AC016825.4, MGC33547 ENSG00000165863 Chromosome 10 open reading frame 82 10 116663696-116670264 Predicted intracellular proteins Evidence at transcript level HPA043022 Approved Mitochondria Mixed Tissue enriched 25 testis: 111.7 ovary: 4.4 Cell line enhanced Hep G2: 1.7;NTERA-2: 1.3;T-47d: 3.5 +HSPA12A FLJ13874, KIAA0417 ENSG00000165868 Heat shock protein family A (Hsp70) member 12A 10 116671192-116849741 Predicted intracellular proteins Evidence at protein level HPA011273, HPA073244 Approved Approved Golgi apparatus
Cytosol Renal cancer:3.61e-7 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 65.0 adrenal gland: 26.7 Cell line enhanced RPTEC TERT1: 46.5 +FRAT1 ENSG00000165879 FRAT1, WNT signaling pathway regulator 10 97319267-97321915 Predicted intracellular proteins Evidence at protein level CAB046472, HPA055258 Approved Approved Vesicles
Cytosol Renal cancer:6.36e-5 (favourable), Head and neck cancer:2.75e-4 (favourable), Cervical cancer:5.92e-4 (favourable) Expressed in all Mixed spleen: 9.2 Mixed +UBTD1 FLJ11807 ENSG00000165886 Ubiquitin domain containing 1 10 97498868-97571209 Predicted intracellular proteins Evidence at protein level HPA034825 Uncertain Approved Vesicles
Plasma membrane
Cytosol Colorectal cancer:5.54e-4 (unfavourable) Expressed in all Mixed testis: 34.0 Mixed +ANKRD2 ARPP ENSG00000165887 Ankyrin repeat domain 2 10 97572499-97583884 Predicted intracellular proteins Evidence at protein level HPA040842, HPA040884 Enhanced Enhanced Vesicles Tissue enhanced Group enriched 14 heart muscle: 35.9;skeletal muscle: 119.4 kidney: 5.6 Cell line enhanced A-431: 14.1;HaCaT: 11.0;RPTEC TERT1: 10.3 +E2F7 ENSG00000165891 E2F transcription factor 7 12 77021247-77065580 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA064866 Supported Nuclear speckles Mixed Tissue enhanced testis: 5.1 bone marrow: 3.0 Mixed +ARHGAP42 FLJ32810, GRAF3 ENSG00000165895 Rho GTPase activating protein 42 11 100687653-100991937 Predicted intracellular proteins Evidence at protein level HPA039924 Enhanced Approved Nuclear speckles
Cytosol Pancreatic cancer:9.29e-4 (unfavourable) Expressed in all Mixed placenta: 23.7 Cell line enhanced CAPAN-2: 27.8 +ISCA2 HBLD1, ISA2 ENSG00000165898 Iron-sulfur cluster assembly 2 14 74493720-74497106 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030492 Approved Renal cancer:1.68e-7 (favourable), Thyroid cancer:8.98e-5 (favourable) Expressed in all Expressed in all epididymis: 56.6 Expressed in all +OTOGL C12orf64, FLJ90579 ENSG00000165899 Otogelin like 12 80209453-80379090 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA040364, HPA053392 Uncertain Approved Cytosol Tissue enhanced Tissue enriched 5 kidney: 6.2 heart muscle: 1.1 Cell line enhanced SCLC-21H: 1.6;U-2 OS: 1.0;U-87 MG: 2.6 +LARGE2 FLJ35207, GYLTL1B, PP5656 ENSG00000165905 LARGE xylosyl- and glucuronyltransferase 2 11 45921621-45929096 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA056621 Approved Renal cancer:3.04e-12 (favourable) Mixed Tissue enhanced placenta: 52.7 parathyroid gland: 21.6 Cell line enhanced BEWO: 33.3;NTERA-2: 32.6;T-47d: 67.1 +PACSIN3 SDPIII ENSG00000165912 Protein kinase C and casein kinase substrate in neurons 3 11 47177525-47186443 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039480, HPA043904 Approved Approved Supported Plasma membrane
Cytosol Ovarian cancer:2.09e-4 (favourable) Expressed in all Tissue enhanced skeletal muscle: 164.2 heart muscle: 93.6 Mixed +TTC7B TTC7L1 ENSG00000165914 Tetratricopeptide repeat domain 7B 14 90524564-90816479 Predicted intracellular proteins Evidence at protein level HPA058363, HPA059577 Enhanced Supported Plasma membrane Renal cancer:3.20e-6 (favourable) Mixed Expressed in all cerebral cortex: 72.6 Mixed +SLC39A13 FLJ25785 ENSG00000165915 Solute carrier family 39 member 13 11 47407132-47416501 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA043971 Approved Uncertain Cytosol Ovarian cancer:2.73e-5 (unfavourable), Renal cancer:1.96e-4 (favourable), Colorectal cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all placenta: 58.3 Expressed in all +PSMC3 TBP-1, TBP1 ENSG00000165916 Proteasome 26S subunit, ATPase 3 11 47418769-47426473 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006065 Approved Supported Nucleus
Cytosol Renal cancer:4.24e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 119.6 Expressed in all +RAPSN CMS1D, CMS1E, RNF205 ENSG00000165917 Receptor associated protein of the synapse 11 47437757-47449178 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039475 Approved Approved Plasma membrane
Centrosome
Cytosol Mixed Tissue enriched 10 skeletal muscle: 30.0 placenta: 2.9 Group enriched 40 LHCN-M2: 47.4;RH-30: 226.0 +AGBL2 CCP2, FLJ23598 ENSG00000165923 ATP/GTP binding protein like 2 11 47659591-47715389 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007718 Uncertain Mixed Group enriched 7 fallopian tube: 15.3;testis: 22.6 epididymis: 2.8 Cell line enhanced CAPAN-2: 4.0 +TC2N C14orf47, C2CD1, FLJ36557, MTAC2D1, Tac2-N ENSG00000165929 Tandem C2 domains, nuclear 14 91779751-91867536 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027549 Approved Approved Nucleoplasm
Nuclear bodies Renal cancer:4.13e-5 (favourable), Pancreatic cancer:9.86e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 40.3 Cell line enhanced CAPAN-2: 16.8;RT4: 29.2;SK-BR-3: 32.5;T-47d: 20.0 +CPSF2 KIAA1367 ENSG00000165934 Cleavage and polyadenylation specific factor 2 14 92121937-92172145 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024238 Supported Approved Nucleoplasm
Vesicles Liver cancer:4.35e-7 (unfavourable) Expressed in all Expressed in all testis: 47.7 Expressed in all +SMCO2 C12orf70, LOC341346 ENSG00000165935 Single-pass membrane protein with coiled-coil domains 2 12 27466810-27502185 Predicted membrane proteins Evidence at protein level HPA014366 Uncertain Mixed Tissue enhanced testis: 1.3 skin: 0.6 Cell line enhanced HDLM-2: 2.0 +MOAP1 MAP-1, PNMA4 ENSG00000165943 Modulator of apoptosis 1 14 93182196-93184928 Predicted intracellular proteins Evidence at protein level HPA000939 Uncertain Approved Nucleus
Cell Junctions Lung cancer:7.37e-9 (favourable), Renal cancer:3.15e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 86.1 Expressed in all +IFI27L1 FAM14B ENSG00000165948 Interferon alpha inducible protein 27 like 1 14 94081282-94103846 Predicted intracellular proteins Evidence at protein level Expressed in all Tissue enhanced testis: 71.9 ovary: 27.5 Expressed in all +IFI27 FAM14D, ISG12, P27 ENSG00000165949 Interferon alpha inducible protein 27 14 94104836-94116698 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028875 Uncertain Ovarian cancer:8.80e-4 (favourable) Expressed in all Expressed in all spleen: 729.7 Cell line enhanced BJ hTERT+ SV40 Large T+: 1891.1;BJ hTERT+ SV40 Large T+ RasG12V: 1737.9;EFO-21: 516.8 +SERPINA12 OL-64, Vaspin ENSG00000165953 Serpin family A member 12 14 94487274-94517844 Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 10 skin: 349.1 breast: 35.5 Cell line enhanced Hep G2: 1.5 +CLMN FLJ12383, KIAA0500, KIAA1188 ENSG00000165959 Calmin 14 95181940-95319906 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012634 Enhanced Approved Nuclear bodies
Cytosol Renal cancer:2.68e-7 (favourable) Expressed in all Tissue enhanced testis: 48.9 kidney: 14.5 Cell line enhanced WM-115: 15.3 +PDZRN4 DKFZp434B0417, FLJ33777, IMAGE5767589, LNX4 ENSG00000165966 PDZ domain containing ring finger 4 12 41188448-41574590 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042101 Enhanced Tissue enhanced Tissue enhanced seminal vesicle: 19.6 prostate: 9.3 Cell line enriched 6 U-266/70: 2.7 +SLC6A5 GLYT2, NET1 ENSG00000165970 Solute carrier family 6 member 5 11 20599400-20659285 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Not detected Tissue enhanced lung: 1.4 testis: 0.6 Not detected +CCDC38 FLJ40089 ENSG00000165972 Coiled-coil domain containing 38 12 95867048-95942974 Predicted intracellular proteins Evidence at protein level HPA039726 Approved Nucleus
Nucleoli Not detected Tissue enriched 18 testis: 26.3 liver: 1.4 Not detected +NELL1 FLJ45906, IDH3GL ENSG00000165973 Neural EGFL like 1 11 20669551-21575681 Predicted secreted proteins Evidence at protein level HPA051535 Approved Tissue enhanced Tissue enhanced cerebral cortex: 22.9;kidney: 18.8 prostate: 8.8 Cell line enhanced HAP1: 4.3;SH-SY5Y: 2.0;U-2 OS: 1.1;WM-115: 1.2 +PTER ENSG00000165983 Phosphotriesterase related 10 16436943-16513745 Predicted intracellular proteins Evidence at protein level HPA038044, HPA038045 Approved Approved Nucleoplasm
Cytosol Renal cancer:6.52e-6 (favourable), Liver cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 42.7 Mixed +C1QL3 C1ql, C1QTNF13, CTRP13, K100 ENSG00000165985 Complement C1q like 3 10 16513743-16522005 Predicted secreted proteins Evidence at protein level Renal cancer:6.29e-5 (favourable) Mixed Tissue enriched 24 cerebral cortex: 43.3 duodenum: 1.8 Group enriched 10 HDLM-2: 29.9;SCLC-21H: 22.4 +CACNB2 CACNLB2, MYSB ENSG00000165995 Calcium voltage-gated channel auxiliary subunit beta 2 10 18140677-18541869 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA035325, HPA035326 Uncertain Renal cancer:3.56e-5 (favourable) Mixed Mixed cerebral cortex: 26.3 Cell line enhanced HAP1: 8.3;HSkMC: 7.1 +HACD1 CAP, PTPLA ENSG00000165996 3-hydroxyacyl-CoA dehydratase 1 10 17589032-17617377 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced heart muscle: 42.0 smooth muscle: 36.3 Mixed +ARL5B ARL8 ENSG00000165997 ADP ribosylation factor like GTPase 5B 10 18659405-18681639 Predicted intracellular proteins Evidence at protein level HPA027002 Approved Liver cancer:1.15e-4 (unfavourable) Expressed in all Mixed adrenal gland: 27.9 Expressed in all +SMCO4 C11orf75, FN5 ENSG00000166002 Single-pass membrane protein with coiled-coil domains 4 11 93478472-93543508 Predicted membrane proteins Evidence at protein level HPA041120 Uncertain Renal cancer:5.81e-7 (unfavourable) Expressed in all Expressed in all salivary gland: 97.5 Cell line enhanced Karpas-707: 102.3 +CEP295 KIAA1731 ENSG00000166004 Centrosomal protein 295 11 93661639-93730358 Predicted intracellular proteins Evidence at protein level HPA038595, HPA038596, HPA038597 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all testis: 22.2 Expressed in all +KCNC2 Kv3.2 ENSG00000166006 Potassium voltage-gated channel subfamily C member 2 12 75040077-75209868 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA019664, CAB022571 Uncertain Supported Plasma membrane
Cytosol Group enriched Tissue enriched 11 cerebral cortex: 46.4 prostate: 4.3 Not detected +TAF1D JOSD3, MGC5306, TAF(I)41 ENSG00000166012 TATA-box binding protein associated factor, RNA polymerase I subunit D 11 93729948-93784391 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055935, HPA060385 Uncertain Supported Nucleoplasm
Microtubule organizing center Renal cancer:3.17e-7 (unfavourable) Expressed in all Expressed in all gallbladder: 13.8 Expressed in all +ABTB2 ABTB2A, BTBD22, DKFZP586C1619 ENSG00000166016 Ankyrin repeat and BTB domain containing 2 11 34150988-34358008 Predicted intracellular proteins Evidence at protein level HPA020065, HPA030699 Approved Supported Nucleus Renal cancer:3.51e-5 (favourable), Cervical cancer:5.70e-5 (unfavourable) Expressed in all Mixed adrenal gland: 13.0 Mixed +R3HCC1L C10orf28, GIDRP86, PSORT ENSG00000166024 R3H domain and coiled-coil containing 1 like 10 98134624-98244897 Predicted intracellular proteins Evidence at protein level HPA037367 Approved Approved Nucleoplasm
Nuclear speckles Expressed in all Expressed in all testis: 38.9 Expressed in all +AMOTL1 JEAP ENSG00000166025 Angiomotin like 1 11 94706431-94876753 Predicted intracellular proteins Evidence at protein level HPA001196 Approved Supported Cell Junctions
Cytosol Renal cancer:5.03e-6 (favourable) Expressed in all Expressed in all prostate: 52.5 Mixed +HTRA1 ARMD7, HtrA, IGFBP5-protease, PRSS11 ENSG00000166033 HtrA serine peptidase 1 10 122461525-122514908 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036655 Enhanced Supported Plasma membrane Renal cancer:7.90e-7 (unfavourable), Urothelial cancer:5.62e-6 (unfavourable), Glioma:8.66e-4 (unfavourable) Expressed in all Mixed ovary: 503.4 Cell line enhanced ASC diff: 1649.0;HSkMC: 1139.5;LHCN-M2: 1027.1;U-87 MG: 974.2 +LIPC HL, HTGL ENSG00000166035 Lipase C, hepatic type 15 58410569-58569843 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Group enriched Tissue enriched 14 liver: 86.4 kidney: 6.3 Cell line enhanced CACO-2: 6.9;EFO-21: 5.7;Hep G2: 16.4;HMC-1: 6.0;U-2197: 17.2 +CEP57 KIAA0092, Translokin, TSP57 ENSG00000166037 Centrosomal protein 57 11 95789965-95832693 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018315 Approved Supported Microtubules
Cytosol Glioma:3.33e-4 (favourable) Expressed in all Expressed in all testis: 53.9 Expressed in all +TCP11L2 MGC40368 ENSG00000166046 T-complex 11 like 2 12 106301929-106347015 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA039483, HPA042188 Uncertain Supported Nuclear speckles Head and neck cancer:9.52e-4 (favourable) Mixed Expressed in all lung: 25.9 Mixed +PASD1 CT63 ENSG00000166049 PAS domain containing repressor 1 X 151563622-151676739 Predicted intracellular proteins Evidence at protein level HPA011122, HPA011152 Enhanced Supported Nuclear speckles Mixed Tissue enriched 298 testis: 29.8 all non-specific tissues: 0.0 Group enriched 7 BEWO: 33.0;HMC-1: 47.7;U-266/84: 19.0 +SPRED1 FLJ33903, PPP1R147 ENSG00000166068 Sprouty related EVH1 domain containing 1 15 38252326-38357249 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042193, HPA061805 Approved Supported Nucleus Renal cancer:7.37e-5 (unfavourable), Stomach cancer:8.29e-5 (unfavourable), Endometrial cancer:7.08e-4 (favourable) Expressed in all Mixed thyroid gland: 48.2 Mixed +TMCO5A MGC35118, TMCO5 ENSG00000166069 Transmembrane and coiled-coil domains 5A 15 37921939-37967724 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA056530 Enhanced Not detected Tissue enriched 195 testis: 123.0 fallopian tube: 0.6 Not detected +GPR176 Gm1012 ENSG00000166073 G protein-coupled receptor 176 15 39799032-39920892 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA039943, HPA039979 Approved Renal cancer:9.38e-7 (unfavourable), Stomach cancer:6.84e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 18.4 Cell line enhanced BJ hTERT+: 243.3;fHDF/TERT166: 159.0 +JAM3 JAM-C, JAMC ENSG00000166086 Junctional adhesion molecule 3 11 134068925-134152001 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003417, HPA050434 Uncertain Enhanced Golgi apparatus Urothelial cancer:2.68e-4 (unfavourable), Renal cancer:3.73e-4 (unfavourable) Expressed in all Expressed in all placenta: 144.4 Cell line enhanced RH-30: 119.8 +IL25 IL-17E, IL-25, IL17E ENSG00000166090 Interleukin 25 14 23372809-23376403 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB024864 Approved Not detected Not detected testis: 0.3 Not detected +CMTM5 CKLFSF5, FLJ37521 ENSG00000166091 CKLF like MARVEL transmembrane domain containing 5 14 23376808-23379772 Predicted membrane proteins Evidence at protein level HPA052338 Enhanced Approved Golgi apparatus
Vesicles Group enriched Tissue enriched 20 cerebral cortex: 81.3 seminal vesicle: 4.1 Cell line enriched 6 HEL: 73.9 +GLB1L3 FLJ90231 ENSG00000166105 Galactosidase beta 1 like 3 11 134274245-134319564 Predicted intracellular proteins Evidence at protein level HPA039916 Uncertain Lung cancer:1.97e-4 (favourable) Tissue enhanced Tissue enhanced prostate: 14.5;seminal vesicle: 7.0 cerebral cortex: 4.0 Cell line enhanced HEK 293: 5.2;NTERA-2: 3.5;PC-3: 4.3;SCLC-21H: 8.6 +ADAMTS15 ENSG00000166106 ADAM metallopeptidase with thrombospondin type 1 motif 15 11 130448974-130476641 Predicted secreted proteins Evidence at transcript level HPA042867 Uncertain Approved Cytosol Urothelial cancer:5.63e-5 (unfavourable), Glioma:9.00e-4 (favourable), Lung cancer:9.72e-4 (unfavourable) Mixed Tissue enhanced adipose tissue: 30.3;placenta: 23.7 breast: 11.0 Cell line enhanced ASC diff: 49.3;ASC TERT1: 30.1;EFO-21: 34.5 +SVOP DKFZp761H039 ENSG00000166111 SV2 related protein 12 108907741-109021240 Predicted membrane proteins Evidence at protein level HPA016573 Uncertain Group enriched Tissue enriched 15 cerebral cortex: 32.2 adrenal gland: 2.0 Cell line enhanced Karpas-707: 2.0;RPMI-8226: 2.0;SCLC-21H: 1.8;SH-SY5Y: 1.4 +SPATA19 CT132, FLJ25851, SPAS1, spergen1 ENSG00000166118 Spermatogenesis associated 19 11 133840631-133845538 Predicted intracellular proteins Evidence at protein level HPA040082 Enhanced Not detected Tissue enriched 509 testis: 142.8 esophagus: 0.2 Not detected +GPT2 ALT2 ENSG00000166123 Glutamic--pyruvic transaminase 2 16 46884378-46931297 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA051514 Approved Approved Mitochondria Ovarian cancer:3.17e-4 (favourable) Expressed in all Expressed in all esophagus: 85.0 Mixed +AMN amnionless ENSG00000166126 Amnion associated transmembrane protein 14 102922656-102933596 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000817 Approved Renal cancer:9.62e-5 (favourable) Mixed Group enriched 6 colon: 20.0;duodenum: 34.2;kidney: 29.0;small intestine: 70.6 liver: 6.7 Cell line enhanced CACO-2: 6.8;Hep G2: 5.6;U-698: 3.0 +RAB8B ENSG00000166128 RAB8B, member RAS oncogene family 15 63189469-63267782 Predicted intracellular proteins Evidence at protein level HPA074534 Supported Nucleoplasm
Vesicles Renal cancer:2.44e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 50.6 Expressed in all +IKBIP FLJ31051, IKIP ENSG00000166130 IKBKB interacting protein 12 98613405-98645113 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038677, HPA038678, HPA061541 Enhanced Enhanced Endoplasmic reticulum Renal cancer:4.60e-9 (unfavourable), Liver cancer:4.00e-5 (unfavourable) Expressed in all Mixed placenta: 36.6 Expressed in all +RPUSD2 C15orf19, C18B11, FLJ31409 ENSG00000166133 RNA pseudouridylate synthase domain containing 2 15 40569300-40574943 Predicted intracellular proteins Evidence at protein level HPA042079, HPA042194 Approved Approved Nucleoplasm
Microtubules Renal cancer:7.63e-7 (favourable) Expressed in all Mixed lymph node: 7.7 Expressed in all +HIF1AN DKFZp762F1811, FIH1, FLJ20615, FLJ22027 ENSG00000166135 Hypoxia inducible factor 1 alpha subunit inhibitor 10 100529072-100559998 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048742, HPA065302, CAB069903 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 25.7 Expressed in all +NDUFB8 ASHI, CI-ASHI ENSG00000166136 NADH:ubiquinone oxidoreductase subunit B8 10 100523740-100530000 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA003886 Supported Supported Mitochondria Expressed in all Expressed in all heart muscle: 306.4 Expressed in all +ZFYVE19 ANCHR, FLJ14840 ENSG00000166140 Zinc finger FYVE-type containing 19 15 40807086-40815084 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040283, HPA041946 Uncertain Endometrial cancer:7.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 28.3 Expressed in all +PPP1R14D CPI17-like, FLJ20251, GBPI-1, MGC119014, MGC119016 ENSG00000166143 Protein phosphatase 1 regulatory inhibitor subunit 14D 15 40815445-40828709 Predicted intracellular proteins Evidence at protein level HPA041846 Uncertain Renal cancer:3.07e-4 (unfavourable) Tissue enhanced Group enriched 7 colon: 105.5;duodenum: 111.1;gallbladder: 24.2;rectum: 100.0;small intestine: 89.8 appendix: 12.4 Cell line enhanced RPMI-8226: 2.1;RT4: 1.5;U-266/84: 1.4 +SPINT1 HAI, MANSC2 ENSG00000166145 Serine peptidase inhibitor, Kunitz type 1 15 40844018-40858207 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA006903, HPA031178 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.37e-7 (favourable), Breast cancer:6.97e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 217.3 Cell line enhanced BEWO: 311.8;HaCaT: 333.0;RT4: 245.6;SK-BR-3: 418.2;T-47d: 251.3 +FBN1 FBN, MASS, MFS1, OCTD, SGS, WMS ENSG00000166147 Fibrillin 1 15 48408306-48645849 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB002670, HPA017759, HPA021057, CAB058696, CAB068188 Enhanced Approved Cytosol Renal cancer:7.44e-5 (unfavourable), Urothelial cancer:5.11e-4 (unfavourable), Stomach cancer:6.57e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 107.5 adipose tissue: 70.8 Cell line enhanced ASC TERT1: 315.9;fHDF/TERT166: 318.3;U-138 MG: 199.6;U-2197: 276.9 +AVPR1A AVPR1 ENSG00000166148 Arginine vasopressin receptor 1A 12 63142759-63150942 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced adrenal gland: 77.8 adipose tissue: 20.0 Group enriched 8 ASC diff: 3.9;Karpas-707: 9.4;U-266/84: 6.8 +C16orf78 MGC33367 ENSG00000166152 Chromosome 16 open reading frame 78 16 49373823-49399431 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 516 testis: 71.0 spleen: 0.1 Not detected +DEPDC4 DEP.4, FLJ33505 ENSG00000166153 DEP domain containing 4 12 100203669-100267079 Predicted intracellular proteins Evidence at protein level HPA039323 Uncertain Approved Microtubules Mixed Tissue enhanced testis: 7.2 kidney: 1.8 Mixed +LRTM2 ENSG00000166159 Leucine rich repeats and transmembrane domains 2 12 1820267-1836752 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055094 Uncertain Not detected Tissue enriched 47 cerebral cortex: 8.3 testis: 0.1 Group enriched 12 HEL: 7.7;SCLC-21H: 5.2 +OPN1MW2 ENSG00000166160 Opsin 1, medium wave sensitive 2 X 154219756-154233286 Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +BRD7 BP75, CELTIX1 ENSG00000166164 Bromodomain containing 7 16 50313487-50368934 Predicted intracellular proteins Evidence at protein level HPA042389, CAB046458, HPA060171 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:1.55e-4 (favourable), Melanoma:5.38e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 106.6 Expressed in all +CKB CKBB ENSG00000166165 Creatine kinase B 14 103519659-103523111 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001254, CAB047313 Enhanced Supported Cytosol Renal cancer:4.02e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 475.1 Cell line enhanced CACO-2: 340.9;HEK 293: 940.9;SCLC-21H: 678.1 +TRMT61A C14orf172, FLJ40452, GCD14, Gcd14p, hTRM61 ENSG00000166166 TRNA methyltransferase 61A 14 103529184-103537073 Enzymes, Predicted intracellular proteins Evidence at protein level Liver cancer:1.60e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 10.1 Expressed in all +BTRC beta-TrCP1, betaTrCP, bTrCP, bTrCP1, FBXW1A, Fwd1 ENSG00000166167 Beta-transducin repeat containing E3 ubiquitin protein ligase 10 101354033-101557321 Predicted intracellular proteins Evidence at protein level HPA031156, CAB032986 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all cerebral cortex: 34.0 Expressed in all +POLL ENSG00000166169 DNA polymerase lambda 10 101578882-101588270 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA066704 Enhanced Nucleus
Golgi apparatus Expressed in all Expressed in all testis: 49.9 Mixed +BAG5 ENSG00000166170 BCL2 associated athanogene 5 14 103556544-103562831 Predicted intracellular proteins Evidence at protein level HPA016429 Enhanced Supported Vesicles Renal cancer:1.58e-8 (favourable) Expressed in all Tissue enriched 6 testis: 241.5 thyroid gland: 38.5 Expressed in all +DPCD DKFZP566F084, RP11-529I10.4 ENSG00000166171 Deleted in primary ciliary dyskinesia homolog (mouse) 10 101570560-101609668 Predicted intracellular proteins Evidence at protein level HPA036603, HPA036604 Enhanced Approved Nuclear speckles Endometrial cancer:6.57e-4 (favourable) Expressed in all Expressed in all testis: 153.2 Mixed +LARP6 acheron, FLJ11196 ENSG00000166173 La ribonucleoprotein domain family member 6 15 70829130-70854159 Predicted intracellular proteins Evidence at protein level HPA020338, HPA049029 Approved Approved Microtubules
Cytokinetic bridge Renal cancer:9.90e-5 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 84.7 thyroid gland: 40.7 Cell line enhanced U-2197: 216.0 +API5 AAC-11, AAC11, API5L1 ENSG00000166181 Apoptosis inhibitor 5 11 43311963-43344529 Predicted intracellular proteins Evidence at protein level HPA026598 Approved Enhanced Nuclear speckles Renal cancer:1.06e-4 (favourable) Expressed in all Expressed in all thyroid gland: 95.8 Expressed in all +ASPG C14orf76 ENSG00000166183 Asparaginase 14 104085679-104115581 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069761 Enhanced Tissue enhanced Tissue enhanced liver: 29.5 esophagus: 13.9 Not detected +ZNF319 KIAA1388, Zfp319 ENSG00000166188 Zinc finger protein 319 16 57994668-58000453 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052584 Uncertain Approved Nucleus Pancreatic cancer:5.87e-5 (favourable), Liver cancer:1.90e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 13.9 Expressed in all +HPS6 BLOC2S3, FLJ22501 ENSG00000166189 HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 10 102065390-102068038 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040687 Approved Expressed in all Expressed in all fallopian tube: 12.0 Expressed in all +SENP8 DEN1, HsT17512, NEDP1, PRSC2 ENSG00000166192 SUMO/sentrin peptidase family member, NEDD8 specific 15 72114258-72143688 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036273 Approved Approved Nucleoplasm
Vesicles Mixed Tissue enhanced testis: 27.7 thyroid gland: 8.3 Expressed in all +NOLC1 KIAA0035, NOPP130, NOPP140, P130 ENSG00000166197 Nucleolar and coiled-body phosphoprotein 1 10 102152176-102163871 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032654, HPA037366, HPA050388 Supported Enhanced Nucleoli Thyroid cancer:8.25e-5 (unfavourable), Renal cancer:9.19e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 69.2 Expressed in all +ALKBH3 DEPC-1 ENSG00000166199 AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase 11 43880811-43920266 Enzymes, Predicted intracellular proteins Evidence at protein level HPA009674, HPA046489 Approved Enhanced Nucleoplasm
Mitochondria Expressed in all Expressed in all epididymis: 32.4 Mixed +COPS2 ALIEN, CSN2, TRIP15 ENSG00000166200 COP9 signalosome subunit 2 15 49106068-49155661 Predicted intracellular proteins Evidence at protein level HPA016867, HPA018271, HPA061071 Approved Enhanced Vesicles
Cytokinetic bridge Expressed in all Expressed in all thyroid gland: 103.5 Expressed in all +GABRB3 ENSG00000166206 Gamma-aminobutyric acid type A receptor beta3 subunit 15 26543546-26939539 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Mixed Tissue enhanced cerebral cortex: 78.3 gallbladder: 21.5 Cell line enhanced A549: 61.5;HAP1: 28.7;NTERA-2: 48.0;SCLC-21H: 51.8 +SPIC MGC40611, SPI-C ENSG00000166211 Spi-C transcription factor 12 101475421-101486997 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enhanced Tissue enriched 12 spleen: 46.7 lymph node: 3.9 Not detected +TBATA C10orf27, FLJ32820, spatial ENSG00000166220 Thymus, brain and testes associated 10 70771239-70785401 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 27 testis: 32.0 spleen: 1.1 Cell line enriched 28 SK-BR-3: 3.0 +SGPL1 SPL ENSG00000166224 Sphingosine-1-phosphate lyase 1 10 70815961-70881173 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021125, HPA023086 Enhanced Supported Endoplasmic reticulum Expressed in all Expressed in all skin: 34.5 Expressed in all +FRS2 FRS2A, FRS2alpha, SNT-1, SNT1 ENSG00000166225 Fibroblast growth factor receptor substrate 2 12 69470349-69579789 Predicted intracellular proteins Evidence at protein level HPA038323 Approved Cell Junctions Expressed in all Expressed in all parathyroid gland: 27.6 Expressed in all +CCT2 Cctb ENSG00000166226 Chaperonin containing TCP1 subunit 2 12 69585334-69601570 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003197, HPA003198 Enhanced Supported Cytosol Liver cancer:3.61e-9 (unfavourable), Prostate cancer:3.67e-4 (unfavourable), Head and neck cancer:8.38e-4 (unfavourable) Expressed in all Expressed in all testis: 367.6 Expressed in all +PCBD1 DCOH, PCBD, PCD ENSG00000166228 Pterin-4 alpha-carbinolamine dehydratase 1 10 70882280-70888784 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037575, HPA061723 Approved Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all liver: 157.7 Mixed +ARIH1 ARI, HARI, HHARI, UBCH7BP ENSG00000166233 Ariadne RBR E3 ubiquitin protein ligase 1 15 72474326-72602985 Predicted intracellular proteins Evidence at protein level HPA003295, HPA073245 Approved Approved Nucleus
Golgi apparatus Expressed in all Expressed in all testis: 65.4 Expressed in all +C16orf71 DKFZp686H2240, FLJ43261 ENSG00000166246 Chromosome 16 open reading frame 71 16 4734272-4749396 Predicted intracellular proteins Evidence at protein level HPA049468 Enhanced Uncertain Nuclear speckles Endometrial cancer:7.49e-4 (favourable) Mixed Group enriched 17 fallopian tube: 35.8;testis: 113.1 lung: 4.3 Mixed +CLMP ACAM, ASAM, FLJ22415 ENSG00000166250 CXADR like membrane protein 11 123069865-123195281 Disease related genes, Predicted membrane proteins Evidence at protein level Mixed Mixed adipose tissue: 65.1 Cell line enhanced BJ: 143.8;U-138 MG: 227.7 +SCN3B HSA243396 ENSG00000166257 Sodium voltage-gated channel beta subunit 3 11 123629187-123655244 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA041707 Approved Intermediate filaments
Cytosol Tissue enhanced Tissue enriched 11 cerebral cortex: 132.1 adrenal gland: 11.5 Cell line enhanced hTCEpi: 4.6;RH-30: 2.8;SCLC-21H: 7.5;SH-SY5Y: 5.0 +COX11 COX11P ENSG00000166260 COX11, cytochrome c oxidase copper chaperone 17 54951902-54968785 Predicted membrane proteins Evidence at protein level HPA044020 Approved Colorectal cancer:4.30e-4 (favourable) Expressed in all Expressed in all duodenum: 60.8 Expressed in all +ZNF202 ZKSCAN10, ZSCAN42 ENSG00000166261 Zinc finger protein 202 11 123724177-123741675 Predicted intracellular proteins, Transcription factors Evidence at protein level Renal cancer:9.93e-7 (unfavourable), Liver cancer:2.52e-6 (unfavourable) Expressed in all Expressed in all testis: 16.7 Expressed in all +FAM227B C15orf33, FLJ32800 ENSG00000166262 Family with sequence similarity 227 member B 15 49326962-49620931 Predicted intracellular proteins Evidence at protein level HPA049774, HPA061695 Uncertain Approved Nuclear speckles Mixed Expressed in all testis: 21.4 Mixed +STXBP4 MGC50337, Synip ENSG00000166263 Syntaxin binding protein 4 17 54968727-55173632 Predicted intracellular proteins Evidence at protein level CAB007760, HPA022138, HPA022888, HPA024227 Approved Approved Plasma membrane
Cytosol Mixed Mixed parathyroid gland: 12.5 Mixed +CYYR1 C21orf95 ENSG00000166265 Cysteine and tyrosine rich 1 21 26466209-26573284 Predicted membrane proteins Evidence at transcript level CAB034921, HPA067685 Uncertain Approved Nucleoplasm Expressed in all Expressed in all adrenal gland: 60.2 Cell line enhanced AF22: 13.8;NTERA-2: 39.4;RH-30: 16.1;SCLC-21H: 39.7 +CUL5 VACM-1 ENSG00000166266 Cullin 5 11 108008733-108107776 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA002185, CAB017787 Approved Approved Golgi apparatus
Cytosol Renal cancer:1.06e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 25.9 Expressed in all +MYRFL bcm1377, C12orf15, C12orf28, FLJ25056 ENSG00000166268 Myelin regulatory factor-like 12 69825304-69959097 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA049340 Approved Approved Nucleoli Mixed Group enriched 5 duodenum: 23.7;small intestine: 24.0 testis: 4.3 Cell line enhanced NTERA-2: 5.2;T-47d: 11.1 +WBP1L C10orf26, FLJ20154, OPAL1 ENSG00000166272 WW domain binding protein 1-like 10 102743970-102816267 Predicted membrane proteins Evidence at protein level HPA037635, HPA038371 Uncertain Approved Nucleoplasm
Microtubules Renal cancer:1.56e-6 (favourable), Endometrial cancer:4.03e-4 (favourable) Expressed in all Expressed in all thyroid gland: 69.9 Expressed in all +BORCS7 C10orf32, FLJ40752 ENSG00000166275 BLOC-1 related complex subunit 7 10 102854223-102864961 Predicted intracellular proteins Evidence at protein level HPA037648 Approved Approved Nuclear speckles
Cytosol Renal cancer:9.08e-8 (favourable) Expressed in all Expressed in all thyroid gland: 91.5 Expressed in all +C2 ENSG00000166278 Complement C2 6 31897785-31945672 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016775 Supported Renal cancer:2.64e-7 (unfavourable) Tissue enriched Tissue enhanced liver: 86.3;lung: 42.6 placenta: 21.9 Group enriched 5 Hep G2: 30.0;Karpas-707: 94.7 +PLEKHF1 APPD, MGC4090, PHAFIN1, ZFYVE15 ENSG00000166289 Pleckstrin homology and FYVE domain containing 1 19 29665056-29675457 Predicted intracellular proteins Evidence at protein level HPA025925 Uncertain Renal cancer:1.54e-5 (unfavourable), Urothelial cancer:4.54e-4 (favourable) Expressed in all Mixed skeletal muscle: 18.6 Cell line enhanced BEWO: 33.0 +TMEM100 FLJ10970, FLJ37856 ENSG00000166292 Transmembrane protein 100 17 55719627-55732121 Predicted membrane proteins Evidence at protein level HPA055936 Approved Uncertain Nucleoplasm Liver cancer:2.67e-5 (favourable), Renal cancer:1.32e-4 (unfavourable) Mixed Tissue enhanced lung: 131.2;placenta: 78.3 epididymis: 44.5 Cell line enhanced ASC diff: 19.9;ASC TERT1: 13.7;HHSteC: 37.7;HSkMC: 15.0;U-87 MG: 13.6;WM-115: 11.8 +ANAPC16 APC16, bA570G20.3, C10orf104, CENP-27, FLJ33728 ENSG00000166295 Anaphase promoting complex subunit 16 10 72216000-72235860 Predicted intracellular proteins Evidence at protein level HPA037815 Approved Supported Cytosol Expressed in all Expressed in all thyroid gland: 40.2 Expressed in all +SMPD1 ASM ENSG00000166311 Sphingomyelin phosphodiesterase 1 11 6390431-6394998 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Renal cancer:4.57e-6 (favourable), Glioma:1.09e-4 (unfavourable), Pancreatic cancer:7.47e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 63.5 Mixed +APBB1 Fe65, RIR ENSG00000166313 Amyloid beta precursor protein binding family B member 1 11 6395124-6419414 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB022104, HPA038521, HPA038522 Approved Enhanced Plasma membrane Renal cancer:7.44e-13 (favourable), Pancreatic cancer:1.86e-5 (favourable), Liver cancer:2.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 236.5 Cell line enhanced SCLC-21H: 81.4 +SYNPO2L FLJ12921 ENSG00000166317 Synaptopodin 2 like 10 73644881-73663803 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055192, HPA057142 Enhanced Approved Nuclear speckles
Cell Junctions
Cytosol Group enriched Group enriched 12 heart muscle: 168.4;skeletal muscle: 95.9 esophagus: 11.1 Cell line enhanced CACO-2: 3.4;HSkMC: 2.3;RH-30: 3.0;SK-BR-3: 2.5 +NUDT13 DKFZp586P2219 ENSG00000166321 Nudix hydrolase 13 10 73110375-73131828 Predicted intracellular proteins Evidence at transcript level HPA040636 Approved Approved Nucleus Mixed Mixed epididymis,parathyroid gland: 4.7 Mixed +C11orf65 MGC33948 ENSG00000166323 Chromosome 11 open reading frame 65 11 108308519-108467531 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 26 testis: 94.0 epididymis: 3.6 Mixed +TRIM44 DIPB, MC7 ENSG00000166326 Tripartite motif containing 44 11 35662805-35818007 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049053, HPA057633 Approved Approved Vesicles
Plasma membrane Liver cancer:5.24e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 30.7 Mixed +CCDC182 ENSG00000166329 Coiled-coil domain containing 182 17 57744481-57745312 Predicted intracellular proteins Evidence at transcript level HPA023446 Uncertain Not detected Tissue enriched 211 testis: 21.0 all non-specific tissues: 0.0 Not detected +ILK ENSG00000166333 Integrin linked kinase 11 6603708-6610874 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004041, HPA048437 Enhanced Enhanced Cell Junctions
Focal adhesion sites Renal cancer:2.44e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 558.8 Expressed in all +TAF10 TAF2A, TAF2H, TAFII30 ENSG00000166337 TATA-box binding protein associated factor 10 11 6606296-6612667 Predicted intracellular proteins Evidence at protein level HPA004148, CAB022405 Supported Supported Nucleoplasm Renal cancer:1.84e-5 (unfavourable) Expressed in all Expressed in all testis: 133.2 Expressed in all +TPP1 CLN2, SCAR7 ENSG00000166340 Tripeptidyl peptidase 1 11 6612763-6619461 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037709, HPA044868 Enhanced Liver cancer:1.11e-4 (unfavourable), Head and neck cancer:4.31e-4 (unfavourable), Stomach cancer:4.46e-4 (unfavourable) Expressed in all Expressed in all spleen: 206.9 Expressed in all +DCHS1 CDH25, CDHR6, FIB1, FLJ11790, KIAA1773, PCDH16 ENSG00000166341 Dachsous cadherin-related 1 11 6621323-6655854 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA017970, HPA050246 Approved Approved Plasma membrane Renal cancer:9.32e-4 (unfavourable) Expressed in all Mixed endometrium: 29.6 Cell line enhanced AF22: 32.9;HUVEC TERT2: 39.1;REH: 21.3;SH-SY5Y: 34.2 +NETO1 BCTL1, BTCL1 ENSG00000166342 Neuropilin and tolloid like 1 18 72742314-72868146 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA064630 Approved Golgi apparatus Tissue enhanced Tissue enriched 16 cerebral cortex: 64.0 spleen: 4.1 Cell line enhanced MOLT-4: 22.4;REH: 24.8;RPMI-8226: 30.0;RT4: 22.5;SCLC-21H: 43.0 +MSS51 FLJ39565, ZMYND17 ENSG00000166343 MSS51 mitochondrial translational activator 10 73423579-73433561 Predicted intracellular proteins Evidence at protein level HPA038564 Uncertain Vesicles
Cytosol Mixed Group enriched 15 parathyroid gland: 162.6;skeletal muscle: 81.4 heart muscle: 8.3 Mixed +CYB5A CYB5 ENSG00000166347 Cytochrome b5 type A 18 74250847-74292016 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB006333, HPA047548, HPA058547 Enhanced Approved Vesicles
Cytosol Liver cancer:4.15e-4 (favourable), Colorectal cancer:5.23e-4 (favourable) Expressed in all Expressed in all liver: 1260.1 Cell line enhanced ASC diff: 766.9 +USP54 bA137L10.3, bA137L10.4, C10orf29, FLJ37318 ENSG00000166348 Ubiquitin specific peptidase 54 10 73497538-73625953 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047663 Approved Approved Mitochondria Lung cancer:7.00e-4 (favourable) Expressed in all Tissue enhanced thyroid gland: 59.6 cerebral cortex: 30.7 Cell line enhanced PC-3: 29.7 +RAG1 MGC43321, RNF74 ENSG00000166349 Recombination activating 1 11 36510709-36593156 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043939 Supported Nucleus Mixed Tissue enhanced thyroid gland: 4.2 spleen: 3.6 Group enriched 102 MOLT-4: 227.0;REH: 243.3 +POTED A26B3, ANKRD21, CT104.1, POTE, POTE-21, POTE21 ENSG00000166351 POTE ankyrin domain family member D 21 13609858-13641585 Predicted intracellular proteins Evidence at transcript level HPA042822 Uncertain Not detected Tissue enriched 14 testis: 1.3 all non-specific tissues: 0.0 Not detected +C11orf74 FLJ38678, HEPIS, NWC ENSG00000166352 Chromosome 11 open reading frame 74 11 36594493-36659290 Predicted intracellular proteins Evidence at protein level HPA044880 Uncertain Approved Aggresome
Cytosol Expressed in all Expressed in all thyroid gland: 177.5 Mixed +WDR88 PQWD ENSG00000166359 WD repeat domain 88 19 33132090-33175795 Predicted intracellular proteins Evidence at protein level HPA041916, HPA050336 Uncertain Approved Nucleoplasm
Golgi apparatus Mixed Tissue enriched 7 testis: 11.1 cerebral cortex,thyroid gland: 1.6 Mixed +OR10A5 JCG6, OR10A1, OR11-403 ENSG00000166363 Olfactory receptor family 10 subfamily A member 5 11 6845652-6846705 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR2D2 hg27, OR11-610, OR2D1 ENSG00000166368 Olfactory receptor family 2 subfamily D member 2 11 6891490-6892599 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ATP9B ATPIIB ENSG00000166377 ATPase phospholipid transporting 9B (putative) 18 79069285-79378283 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029364 Approved Expressed in all Expressed in all testis: 39.0 Expressed in all +PPFIBP2 Cclp1 ENSG00000166387 PPFIA binding protein 2 11 7513298-7657127 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001935, HPA003911 Approved Approved Mitochondria Renal cancer:5.39e-8 (favourable), Urothelial cancer:1.34e-5 (favourable), Lung cancer:2.26e-5 (favourable), Head and neck cancer:2.32e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 184.8 Cell line enhanced BEWO: 77.4;RT4: 91.3 +MOGAT2 DGAT2L5, FLJ22644, MGAT2 ENSG00000166391 Monoacylglycerol O-acyltransferase 2 11 75717819-75732958 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028834 Uncertain Tissue enhanced Group enriched 12 colon: 12.5;duodenum: 37.2;liver: 12.1;rectum: 12.5;small intestine: 43.6 appendix: 1.9 Group enriched 6 Hep G2: 2.7;RPMI-8226: 1.8 +CYB5R2 ENSG00000166394 Cytochrome b5 reductase 2 11 7665100-7677222 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038962, HPA061707 Enhanced Approved Nucleoplasm
Golgi apparatus Mixed Tissue enhanced testis: 227.5 parathyroid gland: 72.2 Cell line enhanced BJ hTERT+: 101.1;BJ hTERT+ SV40 Large T+: 61.1;BJ hTERT+ SV40 Large T+ RasG12V: 57.7;NTERA-2: 69.5;WM-115: 94.6 +SERPINB7 MEGSIN ENSG00000166396 Serpin family B member 7 18 63752935-63805376 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024200 Enhanced Approved Endoplasmic reticulum
Mitochondria Pancreatic cancer:3.03e-5 (unfavourable) Mixed Tissue enhanced skin: 123.7;tonsil: 34.1 breast: 17.4 Cell line enhanced BJ: 202.3;fHDF/TERT166: 131.6;HaCaT: 363.6;HBF TERT88: 215.1;U-138 MG: 215.5 +KIAA0355 ENSG00000166398 KIAA0355 19 34254537-34355586 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA014570 Uncertain Approved Nucleoplasm Melanoma:2.82e-4 (unfavourable) Expressed in all Expressed in all placenta: 33.2 Mixed +SERPINB8 CAP2, PI8 ENSG00000166401 Serpin family B member 8 18 63969925-64019779 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034300 Enhanced Approved Nucleus
Cytosol Renal cancer:3.31e-5 (unfavourable) Expressed in all Mixed skin: 48.9 Mixed +TUB rd5 ENSG00000166402 Tubby bipartite transcription factor 11 8019244-8106112 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA017997, HPA049019 Uncertain Approved Nucleoli
Microtubule organizing center
Centrosome Renal cancer:2.35e-5 (favourable), Pancreatic cancer:2.85e-4 (favourable) Mixed Mixed cerebral cortex: 51.4 Cell line enhanced HEK 293: 34.0;HeLa: 33.4;SCLC-21H: 65.2;SH-SY5Y: 43.8 +RIC3 AYST720, FLJ11608, PRO1385 ENSG00000166405 RIC3 acetylcholine receptor chaperone 11 8106093-8169055 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA065016 Approved Mixed Mixed parathyroid gland: 28.2 Cell line enhanced NTERA-2: 5.0;SCLC-21H: 9.9;SH-SY5Y: 6.2 +LMO1 RBTN1, RHOM1, TTG1 ENSG00000166407 LIM domain only 1 11 8224304-8268716 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enhanced skeletal muscle: 10.1;skin: 5.9 epididymis: 2.0 Group enriched 6 HeLa: 22.0;SCLC-21H: 14.8;SH-SY5Y: 41.0;SiHa: 8.4 +IDH3A ENSG00000166411 Isocitrate dehydrogenase 3 (NAD(+)) alpha 15 78131498-78171949 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041465, HPA062971 Supported Enhanced Mitochondria Renal cancer:6.49e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 44.1 Expressed in all +WDR72 FLJ38736 ENSG00000166415 WD repeat domain 72 15 53513741-53762878 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA048212, HPA057410, HPA059819 Uncertain Approved Vesicles Renal cancer:3.33e-16 (favourable), Thyroid cancer:1.80e-4 (unfavourable) Mixed Group enriched 6 kidney: 104.7;thyroid gland: 92.1 liver: 16.9 Cell line enhanced A549: 8.9;EFO-21: 5.9;NTERA-2: 5.9;RPMI-8226: 11.9;RPTEC TERT1: 8.1;U-266/70: 5.7 +CRABP1 CRABP, CRABP-I, CRABPI, RBP5 ENSG00000166426 Cellular retinoic acid binding protein 1 15 78340324-78348230 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017203 Approved Supported Endometrial cancer:4.72e-4 (unfavourable) Tissue enhanced Tissue enhanced thyroid gland: 269.2 seminal vesicle: 64.5 Group enriched 7 AF22: 952.0;NTERA-2: 289.5 +PLD4 C14orf175 ENSG00000166428 Phospholipase D family member 4 14 104924816-104937790 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051512 Approved Mixed Mixed lymph node: 13.9 Cell line enhanced HMC-1: 99.3;RPMI-8226: 58.9;THP-1: 143.6 +ZMAT1 KIAA1789 ENSG00000166432 Zinc finger matrin-type 1 X 101882288-101932031 Predicted intracellular proteins Evidence at protein level HPA012827 Enhanced Approved Nucleoplasm Pancreatic cancer:1.72e-5 (favourable) Mixed Tissue enhanced epididymis: 25.8 parathyroid gland: 12.2 Cell line enhanced Karpas-707: 5.9;U-266/70: 3.1 +XRRA1 FLJ00225 ENSG00000166435 X-ray radiation resistance associated 1 11 74807739-74949200 Predicted intracellular proteins Evidence at protein level HPA039263 Supported Nucleoplasm
Nuclear bodies Expressed in all Tissue enhanced testis: 35.5 thyroid gland: 11.8 Cell line enhanced hTERT-HME1: 27.8 +TRIM66 C11orf29, KIAA0298, TIF1D ENSG00000166436 Tripartite motif containing 66 11 8612037-8671866 Predicted intracellular proteins Evidence at protein level HPA027420 Approved Supported Nucleoplasm Renal cancer:3.96e-4 (unfavourable), Pancreatic cancer:8.89e-4 (favourable) Expressed in all Mixed testis: 14.0 Mixed +RNF169 KIAA1991 ENSG00000166439 Ring finger protein 169 11 74748868-74842413 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046138, HPA058368 Uncertain Supported Nuclear speckles Pancreatic cancer:8.04e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 14.8 Expressed in all +RPL27A L27A ENSG00000166441 Ribosomal protein L27a 11 8682411-8714759 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA060776, HPA063379 Supported Supported Endoplasmic reticulum
Cytosol Renal cancer:2.83e-10 (unfavourable), Breast cancer:7.84e-5 (favourable) Expressed in all Expressed in all lymph node: 2813.8 Expressed in all +ST5 DENND2B, HTS1, p126 ENSG00000166444 Suppression of tumorigenicity 5 11 8693351-8910951 Predicted intracellular proteins Evidence at protein level HPA046796 Approved Approved Nucleoplasm Expressed in all Expressed in all endometrium: 194.5 Mixed +CDYL2 FLJ38866 ENSG00000166446 Chromodomain Y-like 2 16 80597906-80804329 Predicted intracellular proteins Evidence at protein level HPA041016 Approved Endometrial cancer:6.13e-4 (favourable) Expressed in all Mixed testis: 21.3 Cell line enhanced HDLM-2: 14.7;HUVEC TERT2: 19.5;MCF7: 15.7;TIME: 28.5 +TMEM130 DKFZp761L1417, FLJ42643 ENSG00000166448 Transmembrane protein 130 7 98846488-98870771 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012928 Uncertain Supported Golgi apparatus Lung cancer:7.84e-4 (favourable) Tissue enhanced Group enriched 9 adrenal gland: 49.1;cerebral cortex: 183.0;testis: 70.7 epididymis: 11.5 Cell line enhanced BJ hTERT+: 5.4;EFO-21: 6.0;NTERA-2: 3.8;SH-SY5Y: 8.3 +PRTG FLJ25756, IGDCC5 ENSG00000166450 Protogenin 15 55611546-55743090 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA032138 Uncertain Approved Vesicles
Plasma membrane
Cytosol Mixed Tissue enhanced thyroid gland: 18.2 testis: 6.7 Cell line enriched 6 AF22: 148.8 +CENPN BM039, C16orf60, FLJ13607, FLJ22660 ENSG00000166451 Centromere protein N 16 81006498-81033114 Predicted intracellular proteins Evidence at protein level HPA052870 Supported Nucleus Pancreatic cancer:1.46e-5 (unfavourable), Renal cancer:4.86e-4 (unfavourable), Lung cancer:6.49e-4 (unfavourable) Expressed in all Mixed prostate: 24.5 Expressed in all +AKIP1 BCA3, C11orf17 ENSG00000166452 A-kinase interacting protein 1 11 8911139-8920084 Predicted intracellular proteins Evidence at protein level HPA061391 Supported Nucleoplasm Liver cancer:6.24e-9 (unfavourable), Endometrial cancer:5.15e-4 (favourable) Expressed in all Expressed in all adrenal gland: 30.5 Expressed in all +ATMIN ASCIZ, KIAA0431, ZNF822 ENSG00000166454 ATM interactor 16 81035847-81047358 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054967, HPA066900 Approved Supported Nuclear bodies Renal cancer:6.80e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 61.3 Expressed in all +C16orf46 FLJ32702 ENSG00000166455 Chromosome 16 open reading frame 46 16 81053497-81077267 Predicted intracellular proteins Evidence at protein level HPA041136, HPA041379 Uncertain Supported Nucleoplasm
Cytosol Mixed Tissue enhanced testis: 10.0 thyroid gland: 4.7 Mixed +TMEM41B KIAA0033 ENSG00000166471 Transmembrane protein 41B 11 9280654-9314780 Predicted membrane proteins Evidence at protein level HPA014946 Uncertain Approved Peroxisomes Liver cancer:9.18e-6 (unfavourable) Expressed in all Mixed thyroid gland: 22.3 Expressed in all +LEO1 ENSG00000166477 LEO1 homolog, Paf1/RNA polymerase II complex component 15 51938025-51971806 Predicted intracellular proteins Evidence at protein level HPA040741, HPA040941 Enhanced Enhanced Nucleoplasm
Nucleoli fibrillar center Expressed in all Expressed in all parathyroid gland: 35.6 Expressed in all +ZNF143 pHZ-1, SBF, STAF ENSG00000166478 Zinc finger protein 143 11 9460319-9528524 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003263, HPA074818 Supported Approved Nucleoplasm
Nuclear bodies
Vesicles Liver cancer:1.76e-5 (unfavourable), Renal cancer:6.78e-4 (unfavourable) Expressed in all Expressed in all testis: 31.1 Expressed in all +TMX3 FLJ20793, KIAA1830, PDIA13, TXNDC10 ENSG00000166479 Thioredoxin related transmembrane protein 3 18 68673688-68715298 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014157 Uncertain Renal cancer:2.87e-4 (unfavourable) Expressed in all Expressed in all lymph node: 31.4 Expressed in all +MFAP4 ENSG00000166482 Microfibrillar associated protein 4 17 19383442-19387240 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA054097 Supported Approved Endoplasmic reticulum Renal cancer:6.83e-7 (unfavourable), Head and neck cancer:3.51e-4 (favourable), Ovarian cancer:4.64e-4 (unfavourable), Urothelial cancer:7.12e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 972.0 Cell line enhanced ASC diff: 262.3;ASC TERT1: 405.8;fHDF/TERT166: 213.0;HHSteC: 224.2;HSkMC: 294.1;MOLT-4: 290.1;SH-SY5Y: 360.1 +WEE1 WEE1A ENSG00000166483 WEE1 G2 checkpoint kinase 11 9573681-9593457 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004619, HPA068845 Approved Approved Nucleoli Renal cancer:5.19e-4 (unfavourable) Expressed in all Expressed in all endometrium: 90.6 Expressed in all +MAPK7 BMK1, ERK5, PRKM7 ENSG00000166484 Mitogen-activated protein kinase 7 17 19377721-19383544 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018561, HPA031031 Uncertain Enhanced Nucleus
Cytosol Liver cancer:1.86e-4 (unfavourable) Expressed in all Mixed testis: 10.6 Mixed +PRKCB PKCB, PRKCB1, PRKCB2 ENSG00000166501 Protein kinase C beta 16 23836001-24220611 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB003843, HPA048321, HPA054203 Approved Supported Nucleoplasm
Cytosol Mixed Tissue enhanced cerebral cortex: 125.4 spleen: 64.5 Cell line enhanced HEL: 145.7;HMC-1: 137.9;K-562: 211.8 +RP11-382A20.3 ENSG00000166503 Hepatoma-derived growth factor-related protein 3 15 83112738-83208018 Predicted intracellular proteins Evidence at protein level HPA040719 Approved Supported Nucleoplasm Mixed Tissue enhanced parathyroid gland: 33.0 cerebral cortex: 19.5 Mixed +NDST2 HSST2, NST2 ENSG00000166507 N-deacetylase and N-sulfotransferase 2 10 73801911-73811798 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051515 Approved Approved Cytosol Mixed Expressed in all spleen: 44.9 Expressed in all +MCM7 CDC47, MCM2, PPP1R104 ENSG00000166508 Minichromosome maintenance complex component 7 7 100092728-100101940 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002163, HPA003898, CAB016312 Enhanced Enhanced Nucleoplasm Cervical cancer:1.28e-4 (favourable), Liver cancer:2.18e-4 (unfavourable) Expressed in all Expressed in all testis: 41.9 Expressed in all +CLEC3A CLECSF1 ENSG00000166509 C-type lectin domain family 3 member A 16 78022515-78066761 Predicted secreted proteins Evidence at protein level HPA051511 Uncertain Breast cancer:1.61e-4 (unfavourable) Tissue enriched Tissue enhanced breast: 12.4;urinary bladder: 8.3 prostate: 3.3 Cell line enhanced MCF7: 2.5;SK-BR-3: 5.5;T-47d: 19.7 +CCDC68 SE57-1 ENSG00000166510 Coiled-coil domain containing 68 18 54901509-54959508 Predicted intracellular proteins Evidence at protein level HPA040865, HPA048197 Supported Approved Golgi apparatus
Cytosol Cervical cancer:4.50e-4 (unfavourable), Renal cancer:5.28e-4 (favourable) Mixed Tissue enhanced placenta: 46.2 small intestine: 27.3 Cell line enhanced HHSteC: 11.3;HSkMC: 10.8;TIME: 22.8 +CLEC4E CLECSF9, mincle ENSG00000166523 C-type lectin domain family 4 member E 12 8533305-8540963 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004935 Uncertain Uncertain Cytosol Mixed Tissue enhanced appendix: 53.9;bone marrow: 49.6;spleen: 44.0 gallbladder: 18.9 Cell line enhanced NB-4: 2.8;RPTEC TERT1: 9.2 +ZNF3 A8-51, FLJ20216, HF.12, KOX25, PP838, Zfp113 ENSG00000166526 Zinc finger protein 3 7 100064033-100082548 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003719 Supported Approved Approved Nucleoplasm Melanoma:1.59e-4 (unfavourable), Urothelial cancer:2.20e-4 (favourable), Lung cancer:5.73e-4 (favourable) Expressed in all Expressed in all fallopian tube: 56.8 Expressed in all +CLEC4D CD368, CLECSF8, Mpcl ENSG00000166527 C-type lectin domain family 4 member D 12 8509475-8522366 Predicted intracellular proteins Evidence at protein level HPA004906 Approved Tissue enriched Group enriched 6 appendix: 10.5;bone marrow: 42.8 cervix, uterine: 4.8 Cell line enhanced NB-4: 1.5;NTERA-2: 9.1;U-937: 4.2 +ZSCAN21 DKFZp434L134, NY-REN-21, Zipro1, ZNF38 ENSG00000166529 Zinc finger and SCAN domain containing 21 7 100049774-100065038 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016948, HPA023591 Uncertain Approved Endoplasmic reticulum Thyroid cancer:4.71e-4 (unfavourable) Expressed in all Expressed in all testis: 20.4 Expressed in all +RIMKLB FAM80B, KIAA1238, NAAGS, NAAGS-I ENSG00000166532 Ribosomal modification protein rimK like family member B 12 8681600-8783095 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059552 Approved Nucleoplasm
Microtubule organizing center Mixed Expressed in all endometrium: 74.7 Cell line enhanced U-698: 113.0 +A2ML1 CPAMD9, FLJ25179, p170 ENSG00000166535 Alpha-2-macroglobulin like 1 12 8822472-8887001 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038847, HPA038848 Enhanced Tissue enhanced Tissue enriched 6 esophagus: 479.2 skin: 85.5 Cell line enhanced HMC-1: 9.6;hTCEpi: 3.9;SK-BR-3: 10.3 +BEAN1 SCA31 ENSG00000166546 Brain expressed, associated with NEDD4, 1 16 66427297-66493529 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA053851 Uncertain Uncertain Nucleoplasm
Centrosome Mixed Mixed cerebral cortex: 2.2 Cell line enhanced AN3-CA: 5.5;BEWO: 2.9;RPTEC TERT1: 4.0;U-87 MG: 3.3 +TK2 SCA31 ENSG00000166548 Thymidine kinase 2, mitochondrial 16 66508003-66552544 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041162 Uncertain Renal cancer:2.18e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 89.9 Mixed +TMED3 C15orf22, p24B, p24g4, p24gamma4 ENSG00000166557 Transmembrane p24 trafficking protein 3 15 79311062-79427432 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA049314, HPA076949 Approved Supported Golgi apparatus Renal cancer:3.73e-4 (unfavourable), Breast cancer:7.71e-4 (unfavourable) Expressed in all Mixed salivary gland: 163.2 Mixed +SLC38A8 ENSG00000166558 Solute carrier family 38 member 8 16 84009667-84042636 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Not detected testis: 0.9 Cell line enriched 5 SCLC-21H: 4.0 +SEC11C SEC11L3, SPC21, SPCS4C ENSG00000166562 SEC11 homolog C, signal peptidase complex subunit 18 59139477-59158836 Enzymes, Predicted membrane proteins Evidence at protein level HPA026816, HPA047533 Approved Approved Nuclear membrane
Golgi apparatus Expressed in all Expressed in all prostate: 271.8 Expressed in all +CPLX4 CPX-IV ENSG00000166569 Complexin 4 18 59275156-59318649 Predicted intracellular proteins Evidence at protein level HPA047627 Supported Not detected Not detected skin,testis: 0.4 Not detected +GALR1 GALNR, GALNR1 ENSG00000166573 Galanin receptor 1 18 77250549-77277896 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enhanced adrenal gland: 2.1;cerebral cortex: 1.7 prostate,seminal vesicle,testis: 0.4 Not detected +TMEM135 FLJ22104 ENSG00000166575 Transmembrane protein 135 11 87037844-87323758 Predicted membrane proteins Evidence at protein level HPA056685, HPA069473 Uncertain Supported Vesicles Renal cancer:9.02e-4 (favourable) Expressed in all Expressed in all adipose tissue: 31.7 Expressed in all +IQCD CFAP84, DRC10 ENSG00000166578 IQ motif containing D 12 113195441-113221094 Predicted intracellular proteins Evidence at protein level HPA046810, HPA048782 Supported Approved Nucleus Pancreatic cancer:3.90e-4 (favourable) Mixed Group enriched 6 fallopian tube: 34.8;testis: 65.4 parathyroid gland: 7.7 Cell line enhanced BJ hTERT+: 22.7 +NDEL1 MITAP1, NDE1L1, NDE2, NUDEL ENSG00000166579 NudE neurodevelopment protein 1 like 1 17 8413131-8490411 Predicted intracellular proteins Evidence at protein level HPA017916 Approved Expressed in all Expressed in all adrenal gland: 81.4 Expressed in all +CENPV CENP-V, p30, PRR6 ENSG00000166582 Centromere protein V 17 16342534-16353656 Predicted intracellular proteins Evidence at protein level HPA042529, HPA042616 Enhanced Expressed in all Mixed testis: 13.6 Cell line enhanced AF22: 98.5;NTERA-2: 98.2 +CDH16 ENSG00000166589 Cadherin 16 16 66908122-66918984 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013526, HPA036260 Enhanced Renal cancer:1.02e-7 (favourable) Tissue enriched Group enriched 8 kidney: 231.3;thyroid gland: 58.0 fallopian tube: 17.2 Cell line enriched 78 RPTEC TERT1: 163.7 +RRAD RAD, REM3 ENSG00000166592 RRAD, Ras related glycolysis inhibitor and calcium channel regulator 16 66921679-66925644 Predicted intracellular proteins Evidence at protein level HPA041755 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Expressed in all Tissue enhanced heart muscle: 98.8;skeletal muscle: 67.5 esophagus: 62.8 Group enriched 8 HDLM-2: 166.9;U-87 MG: 48.4 +FAM96B CGI-128, CIA2B, MIP18 ENSG00000166595 Family with sequence similarity 96 member B 16 66932055-66934423 Predicted intracellular proteins Evidence at protein level HPA041501, HPA041736 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 120.8 Expressed in all +CFAP52 FLJ37528, WDR16, WDRPUH ENSG00000166596 Cilia and flagella associated protein 52 17 9576627-9643459 Predicted intracellular proteins Evidence at protein level HPA023247 Enhanced Mixed Group enriched 9 fallopian tube: 91.8;testis: 22.0 lung: 6.6 Cell line enhanced CAPAN-2: 1.5;MCF7: 1.6;REH: 1.3;T-47d: 1.1 +HSP90B1 GP96, GRP94, TRA1 ENSG00000166598 Heat shock protein 90 beta family member 1 12 103930107-103953645 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003901, CAB005224, HPA008424 Enhanced Enhanced Endoplasmic reticulum Renal cancer:1.03e-10 (unfavourable) Expressed in all Expressed in all thyroid gland: 2386.1 Expressed in all +MC4R ENSG00000166603 Melanocortin 4 receptor 18 60371110-60372775 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA016719 Uncertain Tissue enhanced Group enriched 10 cerebral cortex: 2.9;fallopian tube: 5.0 epididymis: 0.4 Cell line enriched 64 fHDF/TERT166: 75.8 +BLCAP BC10 ENSG00000166619 Bladder cancer associated protein 20 37492472-37527931 Predicted intracellular proteins Evidence at protein level HPA047390 Approved Nucleoli Urothelial cancer:7.28e-5 (favourable), Endometrial cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 224.4 Expressed in all +SERPINB12 YUKOPIN ENSG00000166634 Serpin family B member 12 18 63556160-63567011 Plasma proteins, Predicted intracellular proteins Evidence at protein level Head and neck cancer:1.76e-4 (favourable) Group enriched Tissue enriched 5 skin: 78.3 esophagus: 15.2 Not detected +CHRFAM7A CHRNA7-DR1, D-10 ENSG00000166664 CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion 15 30357766-30393849 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced parathyroid gland: 5.0;testis: 5.4 thyroid gland: 2.5 Cell line enhanced HAP1: 3.9;HEL: 3.3;RH-30: 2.7;SH-SY5Y: 3.8;U-937: 3.1 +ATF7IP2 FLJ12668 ENSG00000166669 Activating transcription factor 7 interacting protein 2 16 10326434-10483638 Predicted intracellular proteins Evidence at protein level HPA041156, HPA041228 Enhanced Liver cancer:5.68e-5 (favourable), Urothelial cancer:8.57e-5 (favourable), Breast cancer:4.98e-4 (favourable) Mixed Tissue enhanced testis: 35.7 lymph node: 10.3 Mixed +MMP10 STMY2 ENSG00000166670 Matrix metallopeptidase 10 11 102770503-102780628 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level CAB002159 Uncertain Approved Plasma membrane
Cytosol Urothelial cancer:7.12e-4 (favourable) Tissue enhanced Tissue enriched 40 endometrium: 443.1 appendix: 11.1 Cell line enhanced BJ: 10.0;HUVEC TERT2: 12.6;SCLC-21H: 5.6 +TVP23A FAM18A, YDR084C ENSG00000166676 Trans-golgi network vesicle protein 23 homolog A 16 10760919-10818794 Predicted membrane proteins Evidence at transcript level HPA060582 Uncertain Approved Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 6.3 ovary: 3.2 Cell line enhanced SH-SY5Y: 2.2 +BEX3 Bex, DXS6984E, HGR74, NADE, NGFRAP1 ENSG00000166681 Brain expressed X-linked 3 X 103376340-103378077 Predicted intracellular proteins Evidence at protein level HPA018886 Approved Supported Cytosol Endometrial cancer:7.23e-5 (unfavourable), Renal cancer:1.28e-4 (favourable), Stomach cancer:3.48e-4 (unfavourable) Expressed in all Expressed in all epididymis: 605.0 Mixed +TMPRSS5 MGC141886, MGC148044 ENSG00000166682 Transmembrane protease, serine 5 11 113687550-113706373 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010992 Approved Nucleoplasm Tissue enhanced Tissue enhanced cerebral cortex: 10.1 salivary gland: 3.0 Cell line enhanced CAPAN-2: 2.9;WM-115: 2.6 +COG1 KIAA1381, LDLB ENSG00000166685 Component of oligomeric golgi complex 1 17 73192632-73208507 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029224 Supported Liver cancer:2.91e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 50.8 Expressed in all +PLEKHA7 DKFZp686M22243 ENSG00000166689 Pleckstrin homology domain containing A7 11 16777317-17014443 Predicted intracellular proteins Evidence at protein level HPA038610, HPA066103 Approved Supported Nucleus
Cell Junctions
Cytosol Renal cancer:1.89e-15 (favourable) Mixed Mixed parathyroid gland: 50.8 Cell line enhanced CAPAN-2: 113.7;HaCaT: 75.7;RT4: 94.4 +ZNF606 FLJ14260, KIAA1852, ZNF328 ENSG00000166704 Zinc finger protein 606 19 57977053-58003349 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041712, HPA043584 Uncertain Supported Nucleoplasm Urothelial cancer:4.75e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 18.9 Cell line enhanced HEK 293: 21.5 +ZCCHC18 PNMA7B, SIZN2 ENSG00000166707 Zinc finger CCHC-type containing 18 X 104112131-104115846 Predicted intracellular proteins Evidence at transcript level HPA034940 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 5.6 ovary: 4.2 Cell line enhanced Karpas-707: 3.3;SH-SY5Y: 3.2 +B2M ENSG00000166710 Beta-2-microglobulin 15 44711477-44718877 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB002572, HPA006361 Enhanced Enhanced Golgi apparatus
Plasma membrane
Cytosol Expressed in all Expressed in all lymph node: 5119.8 Expressed in all +ZNF592 CAMOS, KIAA0211, SCAR5 ENSG00000166716 Zinc finger protein 592 15 84748635-84806432 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020332, HPA021600 Approved Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 16.7 Expressed in all +CASC4 DKFZp459F1927, H63 ENSG00000166734 Cancer susceptibility 4 15 44288729-44415758 Predicted intracellular proteins Evidence at protein level HPA043015, HPA049488 Enhanced Supported Golgi apparatus Renal cancer:1.45e-5 (favourable) Expressed in all Expressed in all thyroid gland: 141.6 Expressed in all +HTR3A 5-HT3A, 5-HT3R, HTR3 ENSG00000166736 5-hydroxytryptamine receptor 3A 11 113974881-113990313 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA069442 Supported Endometrial cancer:1.26e-4 (unfavourable), Cervical cancer:6.26e-4 (favourable) Tissue enriched Group enriched 5 appendix: 2.8;lymph node: 7.8;tonsil: 7.2 small intestine: 1.1 Cell line enhanced CAPAN-2: 5.3;Daudi: 4.2;NTERA-2: 3.6;SCLC-21H: 22.1 +NNMT ENSG00000166741 Nicotinamide N-methyltransferase 11 114257787-114313285 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059180 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:1.02e-6 (unfavourable), Stomach cancer:1.75e-4 (unfavourable), Head and neck cancer:2.07e-4 (unfavourable) Expressed in all Tissue enhanced liver: 197.2 adipose tissue: 107.8 Cell line enhanced HSkMC: 300.0;RPTEC TERT1: 491.7 +ACSM1 BUCS1, MACS1 ENSG00000166743 Acyl-CoA synthetase medium-chain family member 1 16 20623237-20698890 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046291 Uncertain Group enriched Tissue enriched 49 breast: 298.7 prostate: 6.0 Group enriched 11 K-562: 3.2;NTERA-2: 15.6 +AP1G1 ADTG, CLAPG1 ENSG00000166747 Adaptor related protein complex 1 gamma 1 subunit 16 71729000-71809201 Predicted intracellular proteins Evidence at protein level CAB009049, HPA041224 Approved Enhanced Vesicles
Cytosol Renal cancer:2.96e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 88.8 Expressed in all +SLFN5 MGC19764 ENSG00000166750 Schlafen family member 5 17 35243036-35273655 Predicted intracellular proteins Evidence at protein level HPA017760 Approved Approved Nucleoplasm
Vesicles Expressed in all Mixed lymph node: 37.4 Cell line enhanced hTERT-HME1: 113.0 +CATSPER2 ENSG00000166762 Cation channel sperm associated 2 15 43628503-43668118 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Mixed Tissue enhanced testis: 30.8 parathyroid gland: 6.5 Mixed +C16orf45 FLJ32618 ENSG00000166780 Chromosome 16 open reading frame 45 16 15434295-15625028 Predicted intracellular proteins Evidence at protein level HPA041114 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:1.53e-4 (favourable), Renal cancer:1.75e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 171.9 cervix, uterine: 59.6 Cell line enhanced fHDF/TERT166: 72.2;U-87 MG: 109.4 +KIAA0430 LKAP, Marf1, PPP1R34 ENSG00000166783 KIAA0430 16 15594386-15643166 Predicted intracellular proteins Evidence at protein level HPA017992 Approved Supported Golgi apparatus
Vesicles Expressed in all Expressed in all parathyroid gland: 20.6 Expressed in all +SAAL1 FLJ41463 ENSG00000166788 Serum amyloid A like 1 11 18069935-18106091 Predicted intracellular proteins Evidence at protein level HPA039003, HPA039004 Approved Supported Nucleoplasm Renal cancer:5.78e-5 (unfavourable) Expressed in all Expressed in all testis: 23.2 Expressed in all +YPEL4 FLJ30213 ENSG00000166793 Yippee like 4 11 57645087-57649944 Predicted intracellular proteins Evidence at transcript level HPA045621 Uncertain Mixed Tissue enhanced cerebral cortex: 19.0 ovary: 4.3 Cell line enhanced AF22: 3.2;SK-MEL-30: 3.1 +PPIB CYPB, OI9 ENSG00000166794 Peptidylprolyl isomerase B 15 64155812-64163205 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level CAB011487, HPA012720 Enhanced Supported Nucleus
Endoplasmic reticulum Renal cancer:2.02e-11 (unfavourable), Endometrial cancer:1.56e-5 (favourable) Expressed in all Expressed in all thyroid gland: 855.2 Expressed in all +LDHC CT32 ENSG00000166796 Lactate dehydrogenase C 11 18412307-18452058 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045442 Enhanced Mixed Tissue enriched 402 testis: 472.9 thyroid gland: 1.1 Cell line enhanced U-2197: 4.8;U-266/70: 3.5;U-266/84: 3.0 +FAM96A CIA2A, FLJ22875 ENSG00000166797 Family with sequence similarity 96 member A 15 64072559-64094018 Predicted secreted proteins Evidence at protein level HPA040459, HPA063729 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all liver: 106.1 Expressed in all +LDHAL6A LDH6A, MGC23940 ENSG00000166800 Lactate dehydrogenase A like 6A 11 18455824-18479600 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 13 testis: 17.5 skin: 1.3 Cell line enriched 6 HL-60: 8.8 +FAM111A FLJ22794, KIAA1895 ENSG00000166801 Family with sequence similarity 111 member A 11 59142748-59155039 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039529, HPA040176 Approved Approved Nucleus
Nucleoli fibrillar center Renal cancer:1.15e-5 (unfavourable), Urothelial cancer:4.39e-4 (favourable) Expressed in all Expressed in all prostate,spleen: 45.6 Mixed +PCLAF KIAA0101, NS5ATP9, OEATC-1, p15(PAF), PAF15 ENSG00000166803 PCNA clamp associated factor 15 64364311-64387687 Predicted intracellular proteins Evidence at protein level HPA047929 Supported Centrosome Renal cancer:9.77e-15 (unfavourable), Liver cancer:3.26e-5 (unfavourable) Expressed in all Tissue enhanced bone marrow: 76.2;lymph node: 50.8 tonsil: 36.9 Mixed +KIF7 JBTS12 ENSG00000166813 Kinesin family member 7 15 89608789-89655451 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043145 Approved Endometrial cancer:3.80e-5 (unfavourable) Expressed in all Mixed endometrium: 5.3 Cell line enhanced U-2197: 36.1 +LDHD ENSG00000166816 Lactate dehydrogenase D 16 75111860-75116771 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041766, HPA048639, HPA066148 Enhanced Approved Cytosol Renal cancer:2.95e-14 (favourable), Liver cancer:5.61e-4 (favourable) Expressed in all Mixed kidney: 34.0 Cell line enhanced HMC-1: 13.2;T-47d: 27.8;U-266/70: 8.9 +PLIN1 PLIN ENSG00000166819 Perilipin 1 15 89664365-89679427 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024299, CAB033821, CAB037333 Enhanced Uncertain Peroxisomes Tissue enhanced Tissue enriched 10 adipose tissue: 1012.5 breast: 100.6 Cell line enriched 157 ASC diff: 142.8 +PEX11A MGC119947, MGC138534, PEX11-ALPHA ENSG00000166821 Peroxisomal biogenesis factor 11 alpha 15 89677764-89690783 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Head and neck cancer:2.57e-4 (unfavourable) Expressed in all Mixed prostate: 29.3 Cell line enhanced SK-BR-3: 40.6 +TMEM170A FLJ37611, TMEM170 ENSG00000166822 Transmembrane protein 170A 16 75443054-75465497 Predicted membrane proteins, Transporters Evidence at protein level HPA055071 Uncertain Renal cancer:2.36e-9 (favourable) Expressed in all Expressed in all testis: 32.4 Expressed in all +MESP1 bHLHc5, MGC10676 ENSG00000166823 Mesoderm posterior bHLH transcription factor 1 15 89748661-89751310 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA069981 Supported Nucleus
Nucleoli Group enriched Tissue enhanced adipose tissue: 4.8;prostate: 4.8 cerebral cortex: 1.4 Cell line enhanced A-431: 3.1;HDLM-2: 2.9;HEK 293: 2.7;PC-3: 5.2;SCLC-21H: 3.0 +ANPEP CD13, gp150, LAP1, p150, PEPN ENSG00000166825 Alanyl aminopeptidase, membrane 15 89784889-89815401 CD markers, Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002417, HPA004625 Enhanced Supported Plasma membrane Expressed in all Group enriched 9 duodenum: 2386.4;small intestine: 2133.7 kidney: 263.2 Cell line enhanced BJ hTERT+: 958.3;HUVEC TERT2: 770.8;TIME: 760.6;U-2197: 926.0 +SCNN1G ENaCgamma, SCNEG ENSG00000166828 Sodium channel epithelial 1 gamma subunit 16 23182715-23216883 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA071194 Supported Nucleoplasm
Plasma membrane Renal cancer:3.20e-7 (unfavourable) Tissue enhanced Tissue enhanced cervix, uterine: 24.6;kidney: 46.7 thyroid gland: 9.5 Group enriched 5 hTCEpi: 33.4;RT4: 17.1 +RBPMS2 ENSG00000166831 RNA binding protein with multiple splicing 2 15 64739892-64775587 Predicted intracellular proteins Evidence at protein level Renal cancer:1.48e-4 (favourable) Expressed in all Tissue enhanced heart muscle: 134.9 seminal vesicle: 63.9 Cell line enhanced AF22: 38.7;AN3-CA: 51.6;HEL: 77.7;NTERA-2: 76.7 +NAV2 FLJ10633, FLJ11030, FLJ23707, HELAD1, KIAA1419, POMFIL2, RAINB1 ENSG00000166833 Neuron navigator 2 11 19350724-20121598 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011755, HPA011891 Approved Supported Nucleoplasm Expressed in all Mixed heart muscle: 39.2 Cell line enhanced hTERT-HME1: 69.3;SH-SY5Y: 87.7 +ANKDD1A FLJ25870 ENSG00000166839 Ankyrin repeat and death domain containing 1A 15 64911902-64958700 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA040757 Approved Approved Nucleoplasm Mixed Mixed spleen: 15.0 Cell line enhanced Karpas-707: 17.4;RT4: 14.8;U-266/84: 17.5 +GLYATL1 FLJ34646, MGC15397 ENSG00000166840 Glycine-N-acyltransferase like 1 11 58905398-59043527 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039501 Supported Uncertain Golgi apparatus
Cytosol Renal cancer:3.03e-5 (favourable), Liver cancer:3.69e-4 (favourable) Group enriched Group enriched 13 kidney: 145.2;liver: 298.1 prostate: 17.4 Cell line enhanced CACO-2: 1.6;Daudi: 3.5;RPTEC TERT1: 1.2;U-2197: 1.1 +C18orf54 LAS2, MGC33382 ENSG00000166845 Chromosome 18 open reading frame 54 18 54357917-54385218 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040704 Approved Nucleoplasm Mixed Tissue enriched 8 testis: 30.4 placenta: 3.8 Mixed +DCTN5 MGC3248, p25 ENSG00000166847 Dynactin subunit 5 16 23641392-23677455 Predicted intracellular proteins Evidence at protein level HPA042003, HPA063710 Approved Approved Nucleoplasm
Nuclear membrane Liver cancer:4.02e-4 (unfavourable), Renal cancer:4.48e-4 (favourable) Expressed in all Expressed in all cerebral cortex,testis: 38.1 Expressed in all +TERF2IP RAP1 ENSG00000166848 TERF2 interacting protein 16 75647786-75761872 Predicted intracellular proteins Evidence at protein level HPA006719, CAB018660, CAB018749 Supported Supported Nucleoplasm
Nuclear bodies Renal cancer:2.15e-5 (favourable), Ovarian cancer:6.14e-5 (favourable), Pancreatic cancer:1.46e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 221.2 Expressed in all +PLK1 PLK ENSG00000166851 Polo like kinase 1 16 23677656-23690367 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA051638, HPA053229 Approved Renal cancer:0.00e+0 (unfavourable), Liver cancer:2.70e-7 (unfavourable), Lung cancer:2.28e-5 (unfavourable), Pancreatic cancer:4.12e-4 (unfavourable) Expressed in all Tissue enhanced testis: 44.2 lymph node: 32.8 Expressed in all +CLPX ENSG00000166855 Caseinolytic mitochondrial matrix peptidase chaperone subunit 15 65148219-65185342 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040262, HPA048199 Approved Enhanced Mitochondria Renal cancer:1.93e-9 (favourable) Expressed in all Expressed in all skin: 17.7 Expressed in all +GPR182 ADMR, AM-R, G10D, hrhAMR ENSG00000166856 G protein-coupled receptor 182 12 56994446-56998441 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027037 Enhanced Not detected Tissue enhanced spleen: 12.2;testis: 6.7 liver: 2.0 Cell line enhanced RH-30: 1.8 +ZBTB39 KIAA0352, ZNF922 ENSG00000166860 Zinc finger and BTB domain containing 39 12 56998834-57006446 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016866, HPA020306 Uncertain Approved Vesicles Expressed in all Mixed testis: 13.4 Expressed in all +CACNG2 MGC138502, MGC138504, stargazin ENSG00000166862 Calcium voltage-gated channel auxiliary subunit gamma 2 22 36563921-36703558 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Not detected Tissue enriched 13 cerebral cortex: 15.3 adrenal gland: 1.2 Group enriched 11 SCLC-21H: 3.3;SH-SY5Y: 1.3 +TAC3 NKB, NKNB, ZNEUROK1 ENSG00000166863 Tachykinin 3 12 57010000-57028883 Disease related genes, Predicted secreted proteins Evidence at protein level HPA045919 Supported Approved Approved Vesicles Tissue enriched Tissue enriched 23 placenta: 617.0 cerebral cortex: 27.2 Cell line enhanced K-562: 13.1;SCLC-21H: 2.7 +MYO1A DFNA48, MYHL ENSG00000166866 Myosin IA 12 57028517-57051198 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053490 Enhanced Group enriched Group enriched 13 colon: 67.8;duodenum: 333.2;rectum: 71.8;small intestine: 338.4 stomach: 16.1 Cell line enhanced BEWO: 1.9;CACO-2: 6.6;Hep G2: 3.7 +CHP2 ENSG00000166869 Calcineurin like EF-hand protein 2 16 23754627-23758951 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB072806 Approved Tissue enhanced Group enriched 10 colon: 119.1;duodenum: 252.0;rectum: 127.6;skin: 143.8;small intestine: 227.3 cervix, uterine: 17.1 Cell line enhanced hTERT-HME1: 4.5;NB-4: 4.6 +NEMP1 KIAA0286, TMEM194, TMEM194A ENSG00000166881 Nuclear envelope integral membrane protein 1 12 57055643-57088063 Predicted membrane proteins Evidence at protein level HPA014394 Uncertain Approved Nucleoplasm Renal cancer:1.09e-5 (unfavourable), Liver cancer:1.93e-4 (unfavourable) Expressed in all Mixed lymph node: 14.5 Expressed in all +OR4D6 ENSG00000166884 Olfactory receptor family 4 subfamily D member 6 11 59456938-59457991 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.1 Not detected +NAB2 MADER ENSG00000166886 NGFI-A binding protein 2 12 57088894-57095476 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004510, HPA027464 Approved Approved Nucleus
Cytosol Renal cancer:9.38e-6 (unfavourable), Breast cancer:7.41e-4 (favourable) Expressed in all Expressed in all ovary: 39.3 Expressed in all +VPS39 KIAA0770, VAM6 ENSG00000166887 VPS39, HOPS complex subunit 15 42158701-42208316 Plasma proteins, Predicted intracellular proteins Evidence at protein level Endometrial cancer:3.21e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 65.7 Expressed in all +STAT6 D12S1644, IL-4-STAT ENSG00000166888 Signal transducer and activator of transcription 6 12 57095408-57132139 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001861 Approved Enhanced Nucleoplasm
Cytosol Urothelial cancer:1.14e-4 (favourable), Endometrial cancer:1.69e-4 (favourable), Thyroid cancer:7.76e-4 (favourable) Expressed in all Expressed in all skin: 163.9 Mixed +PATL1 FLJ36874, Pat1b ENSG00000166889 PAT1 homolog 1, processing body mRNA decay factor 11 59636716-59668980 Predicted intracellular proteins Evidence at protein level HPA039030 Uncertain Supported Cytoplasmic bodies Pancreatic cancer:2.04e-4 (unfavourable), Colorectal cancer:4.56e-4 (favourable) Expressed in all Expressed in all bone marrow: 37.0 Expressed in all +ATP23 KUB3, XRCC6BP1 ENSG00000166896 ATP23 metallopeptidase and ATP synthase assembly factor homolog 12 57941541-57957269 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035804, HPA043204 Uncertain Enhanced Vesicles
Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.44e-5 (unfavourable) Expressed in all Tissue enhanced testis: 26.8 rectum: 5.5 Expressed in all +ELFN2 dJ63G5.3, KIAA1904, LRRC62, PPP1R29 ENSG00000166897 Extracellular leucine rich repeat and fibronectin type III domain containing 2 22 37367960-37427470 Predicted membrane proteins Evidence at protein level HPA000781 Approved Approved Nucleoplasm
Vesicles Renal cancer:7.21e-4 (unfavourable) Mixed Tissue enriched 7 cerebral cortex: 24.3 testis: 3.4 Cell line enhanced RPTEC TERT1: 16.3;U-2 OS: 25.4 +STX3 STX3A ENSG00000166900 Syntaxin 3 11 59755059-59805882 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002191, HPA069176 Approved Approved Nucleus
Nuclear bodies
Golgi apparatus
Cytosol Liver cancer:8.41e-7 (unfavourable), Renal cancer:1.14e-6 (favourable) Expressed in all Expressed in all placenta: 72.4 Mixed +MRPL16 FLJ20484, PNAS-111 ENSG00000166902 Mitochondrial ribosomal protein L16 11 59806135-59810872 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA054133 Supported Breast cancer:1.04e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 71.6 Expressed in all +PIP4K2C FLJ22055, PIP5K2C ENSG00000166908 Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma 12 57591174-57603418 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028658, HPA058551 Approved Approved Vesicles Renal cancer:2.06e-6 (favourable), Liver cancer:7.98e-4 (unfavourable) Expressed in all Expressed in all epididymis: 109.1 Mixed +MTMR10 FLJ20313 ENSG00000166912 Myotubularin related protein 10 15 30938941-30991607 Predicted intracellular proteins Evidence at protein level HPA006081 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:7.77e-12 (favourable) Expressed in all Expressed in all placenta: 36.9 Expressed in all +YWHAB YWHAA ENSG00000166913 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta 20 44885676-44908532 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003759, HPA007925, HPA011212 Enhanced Supported Cytosol Liver cancer:1.91e-6 (unfavourable), Renal cancer:2.52e-5 (favourable), Endometrial cancer:5.46e-4 (unfavourable), Lung cancer:6.01e-4 (unfavourable), Head and neck cancer:6.14e-4 (unfavourable), Breast cancer:9.18e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 445.0 Expressed in all +C15orf48 NMES1 ENSG00000166920 Chromosome 15 open reading frame 48 15 45430529-45448761 Predicted intracellular proteins Evidence at protein level HPA012943 Enhanced Expressed in all Tissue enhanced colon: 716.6;rectum: 832.9 small intestine: 330.3 Cell line enhanced A-431: 52.4;CAPAN-2: 96.3 +SCG5 7B2, SGNE1, SgV ENSG00000166922 Secretogranin V 15 32641676-32697098 Predicted secreted proteins Evidence at protein level HPA013136, HPA074618 Enhanced Renal cancer:4.51e-9 (unfavourable), Head and neck cancer:9.64e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 233.7;parathyroid gland: 192.7 adrenal gland: 80.4 Group enriched 6 HHSteC: 22.6;HSkMC: 24.3;NTERA-2: 15.6;SCLC-21H: 37.1;SH-SY5Y: 38.6;U-87 MG: 46.3 +GREM1 CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS ENSG00000166923 Gremlin 1, DAN family BMP antagonist 15 32717974-32745107 Disease related genes, Predicted secreted proteins Evidence at protein level HPA007526 Uncertain Lung cancer:4.46e-4 (unfavourable) Tissue enhanced Tissue enhanced gallbladder: 92.4;smooth muscle: 67.3 urinary bladder: 22.4 Cell line enhanced BJ: 150.1;BJ hTERT+: 219.5;BJ hTERT+ SV40 Large T+ RasG12V: 161.4;fHDF/TERT166: 426.8;hTEC/SVTERT24-B: 168.1 +NYAP1 C7orf51, FLJ37538, KIAA1486L ENSG00000166924 Neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1 7 100483927-100494799 Predicted intracellular proteins Evidence at protein level HPA022251 Uncertain Supported Golgi apparatus
Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 25.1;testis: 7.7 adrenal gland: 3.3 Cell line enhanced HUVEC TERT2: 3.2;SH-SY5Y: 9.9 +TSC22D4 THG-1, TILZ2 ENSG00000166925 TSC22 domain family member 4 7 100463359-100479279 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA006757 Uncertain Approved Cytosol Colorectal cancer:2.66e-4 (unfavourable), Liver cancer:9.45e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 278.2 Expressed in all +MS4A6E ENSG00000166926 Membrane spanning 4-domains A6E 11 60334831-60396596 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 37 testis: 61.9 appendix: 1.6 Not detected +MS4A7 CD20L4, CFFM4, MS4A8 ENSG00000166927 Membrane spanning 4-domains A7 11 60378482-60395951 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017418, CAB026387 Approved Expressed in all Tissue enhanced spleen: 316.0 lung: 125.0 Cell line enriched 25 THP-1: 78.2 +MS4A14 DKFZp434H092, FLJ32856, MS4A16, NYD-SP21 ENSG00000166928 Membrane spanning 4-domains A14 11 60378530-60417756 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at transcript level Mixed Tissue enriched 12 testis: 91.8 spleen: 7.6 Cell line enriched 23 THP-1: 6.3 +MS4A5 CD20L2 ENSG00000166930 Membrane spanning 4-domains A5 11 60429589-60455214 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA043732 Uncertain Not detected Tissue enriched 280 testis: 73.1 duodenum: 0.2 Not detected +DIS3L DIS3L1, FLJ38088, KIAA1955, MGC4562 ENSG00000166938 DIS3 like exosome 3'-5' exoribonuclease 15 66293217-66333898 Predicted intracellular proteins Evidence at protein level HPA041805 Approved Approved Plasma membrane
Centrosome
Cytosol Expressed in all Expressed in all parathyroid gland: 25.6 Expressed in all +CCNDBP1 DIP1, GCIP, HHM ENSG00000166946 Cyclin D1 binding protein 1 15 43185118-43197176 Predicted intracellular proteins Evidence at protein level CAB020664, HPA041065 Supported Enhanced Nucleoplasm Renal cancer:2.06e-4 (favourable) Expressed in all Mixed bone marrow: 7.6 Cell line enhanced HEL: 4.6 +EPB42 MGC116735, MGC116737, PA ENSG00000166947 Erythrocyte membrane protein band 4.2 15 43106225-43221283 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040261 Supported Not detected Tissue enriched 13 bone marrow: 57.6 placenta: 4.5 Cell line enriched 96 HEL: 74.7 +TGM6 dJ734P14.3, SCA35, TGM3L, TGY ENSG00000166948 Transglutaminase 6 20 2380908-2432753 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA059196 Uncertain Not detected Not detected tonsil: 0.4 Not detected +SMAD3 HsT17436, JV15-2, MADH3 ENSG00000166949 SMAD family member 3 15 67063763-67195195 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB008094, HPA046386, HPA067203, CAB069409 Approved Enhanced Nucleoplasm
Cytosol Pancreatic cancer:2.48e-4 (unfavourable) Expressed in all Expressed in all esophagus: 54.2 Expressed in all +MS4A8 CD20L5, MS4A4, MS4A8B ENSG00000166959 Membrane spanning 4-domains A8 11 60699574-60715811 Predicted membrane proteins Evidence at protein level HPA007318, HPA007319 Enhanced Tissue enhanced Tissue enhanced duodenum: 186.5;fallopian tube: 226.5;small intestine: 210.9 stomach: 49.1 Cell line enhanced SCLC-21H: 1.1 +CCDC178 C18orf34, FLJ44050 ENSG00000166960 Coiled-coil domain containing 178 18 32937402-33441101 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced testis: 27.7 spleen: 10.6 Group enriched 15 HUVEC TERT2: 4.2;U-87 MG: 4.3 +MS4A15 ENSG00000166961 Membrane spanning 4-domains A15 11 60756953-60776732 Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enriched 11 lung: 71.4 endometrium: 6.2 Cell line enhanced HEL: 6.6;MOLT-4: 2.7;U-266/70: 7.9;U-266/84: 3.3 +MAP1A MAP1L ENSG00000166963 Microtubule associated protein 1A 15 43510958-43531620 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039063, HPA039064, HPA066488 Enhanced Approved Cytosol Thyroid cancer:1.09e-5 (unfavourable), Urothelial cancer:1.66e-5 (unfavourable), Renal cancer:6.59e-5 (unfavourable) Tissue enhanced Tissue enriched 9 cerebral cortex: 165.6 smooth muscle: 18.9 Cell line enhanced fHDF/TERT166: 72.9;U-87 MG: 119.0 +RCCD1 MGC14386 ENSG00000166965 RCC1 domain containing 1 15 90954870-90963125 Predicted intracellular proteins Evidence at protein level HPA039683, HPA040776 Enhanced Enhanced Plasma membrane
Cytosol Expressed in all Mixed parathyroid gland: 8.9 Mixed +AKTIP FLJ13258, FTS ENSG00000166971 AKT interacting protein 16 53491040-53504411 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041794, HPA046300 Approved Renal cancer:1.18e-14 (favourable) Expressed in all Expressed in all parathyroid gland: 82.4 Expressed in all +MAPRE2 EB1, EB2, RP1 ENSG00000166974 Microtubule associated protein RP/EB family member 2 18 34976928-35143470 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016738, HPA016739 Enhanced Uncertain Nucleoplasm Expressed in all Expressed in all cerebral cortex: 174.6 Mixed +EVA1C B18, B19, C21orf63, C21orf64, FAM176C, PRED34 ENSG00000166979 Eva-1 homolog C 21 32412006-32515397 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015720, HPA029944, CAB034174 Enhanced Head and neck cancer:5.06e-4 (favourable) Expressed in all Mixed fallopian tube: 25.5 Cell line enhanced A549: 16.5;CAPAN-2: 16.0;U-87 MG: 14.9 +TCP10L2 bA517H2.3 ENSG00000166984 T-complex 10-like 2 6 167146414-167196913 Predicted intracellular proteins Evidence at transcript level CAB034197, HPA044709 Uncertain Not detected Tissue enhanced epididymis: 1.6;testis: 1.5 small intestine: 0.3 Not detected +MARS CMT2U, MetRS, SPG70 ENSG00000166986 Methionyl-tRNA synthetase 12 57475445-57517569 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004125, CAB017097 Supported Approved Enhanced Cytosol Liver cancer:4.55e-7 (unfavourable), Renal cancer:1.59e-4 (unfavourable), Breast cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all testis: 66.7 Expressed in all +MBD6 KIAA1887 ENSG00000166987 Methyl-CpG binding domain protein 6 12 57520710-57530148 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038948, HPA038949 Uncertain Enhanced Nucleus Expressed in all Expressed in all testis: 65.8 Expressed in all +CNPY4 MGC40499, PRAT4B ENSG00000166997 Canopy FGF signaling regulator 4 7 100119613-100125511 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA014166, HPA025240 Uncertain Approved Vesicles Renal cancer:3.59e-5 (unfavourable), Liver cancer:3.99e-4 (unfavourable) Expressed in all Mixed endometrium: 34.8 Expressed in all +PDIA3 ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC ENSG00000167004 Protein disulfide isomerase family A member 3 15 43746392-43773279 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002645, HPA003230, CAB011199, CAB075744 Enhanced Enhanced Endoplasmic reticulum Renal cancer:2.11e-8 (unfavourable), Head and neck cancer:8.95e-5 (unfavourable), Endometrial cancer:2.05e-4 (favourable) Expressed in all Expressed in all thyroid gland: 91.5 Expressed in all +NUDT21 CFIM25, CPSF5 ENSG00000167005 Nudix hydrolase 21 16 56429133-56452199 Predicted intracellular proteins Evidence at protein level HPA019863, HPA074228 Uncertain Supported Nuclear bodies
Microtubule organizing center Expressed in all Expressed in all testis: 128.9 Expressed in all +NAT16 C7orf52, FLJ39237 ENSG00000167011 N-acetyltransferase 16 (putative) 7 101170493-101180276 Predicted intracellular proteins Evidence at transcript level HPA021918 Uncertain Approved Nucleus Tissue enhanced Group enriched 8 cerebral cortex: 5.1;thyroid gland: 3.0 pancreas: 0.5 Cell line enhanced RPMI-8226: 1.6;SH-SY5Y: 3.6;SK-MEL-30: 2.0;U-2 OS: 3.1;U-87 MG: 1.6 +TERB2 C15orf43, MGC33951 ENSG00000167014 Telomere repeat binding bouquet formation protein 2 15 44956702-44979229 Predicted intracellular proteins Evidence at protein level HPA041780, HPA041941 Uncertain Nucleus
Nucleoli
Centrosome Not detected Tissue enriched 25 testis: 40.1 breast: 1.6 Not detected +NKX3-1 BAPX2, NKX3.1, NKX3A ENSG00000167034 NK3 homeobox 1 8 23678693-23682927 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA078571 Enhanced Tissue enriched Tissue enriched 11 prostate: 485.5 testis: 45.0 Cell line enhanced SiHa: 27.8;U-138 MG: 25.5 +SGSM1 KIAA1941, RUTBC2 ENSG00000167037 Small G protein signaling modulator 1 22 24806169-24927578 Predicted intracellular proteins Evidence at protein level HPA003986 Approved Mixed Tissue enhanced cerebral cortex: 14.8;parathyroid gland: 19.0 fallopian tube: 7.6 Cell line enhanced RPMI-8226: 1.5;SCLC-21H: 2.4;SH-SY5Y: 1.4 +DUSP18 DUSP20 ENSG00000167065 Dual specificity phosphatase 18 22 30652051-30667890 Enzymes, Predicted intracellular proteins Evidence at protein level CAB034070, HPA051349 Approved Supported Nucleoplasm Mixed Mixed testis: 22.3 Expressed in all +TEF KIAA1655 ENSG00000167074 TEF, PAR bZIP transcription factor 22 41367333-41399326 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Renal cancer:3.47e-11 (favourable) Expressed in all Mixed parathyroid gland: 58.6 Expressed in all +MEI1 MGC40042, SPATA38 ENSG00000167077 Meiotic double-stranded break formation protein 1 22 41699499-41799456 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049240 Approved Uncertain Nucleoplasm
Plasma membrane Cervical cancer:1.59e-6 (favourable) Tissue enhanced Tissue enhanced testis: 18.6 spleen: 10.7 Cell line enhanced HMC-1: 7.9;Karpas-707: 21.6;U-266/70: 24.1 +B4GALNT2 Cad, GALGT2, Sda ENSG00000167080 Beta-1,4-N-acetyl-galactosaminyltransferase 2 17 49132460-49176840 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015721 Approved Renal cancer:1.29e-5 (favourable) Mixed Tissue enhanced colon: 33.3 rectum: 14.9 Mixed +PBX3 ENSG00000167081 PBX homeobox 3 9 125747345-125967377 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003881 Supported Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 340.6 Mixed +GNGT2 GNG9 ENSG00000167083 G protein subunit gamma transducin 2 17 49202791-49210574 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA043381 Supported Renal cancer:3.11e-4 (unfavourable) Mixed Mixed spleen: 26.3 Cell line enhanced Daudi: 59.2;HDLM-2: 66.4;RH-30: 24.6 +PHB PHB1 ENSG00000167085 Prohibitin 17 49404049-49414905 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003280 Supported Supported Vesicles
Mitochondria Head and neck cancer:1.58e-4 (unfavourable), Renal cancer:3.77e-4 (favourable), Liver cancer:9.91e-4 (unfavourable) Expressed in all Expressed in all kidney: 202.4 Expressed in all +SNRPD1 HsT2456, Sm-D1, SNRPD ENSG00000167088 Small nuclear ribonucleoprotein D1 polypeptide 18 21612267-21633524 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040516 Supported Ovarian cancer:7.90e-6 (favourable), Liver cancer:1.82e-5 (unfavourable) Expressed in all Expressed in all lymph node: 81.2 Expressed in all +TTC16 FLJ32780 ENSG00000167094 Tetratricopeptide repeat domain 16 9 127716066-127731600 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 12 fallopian tube: 10.9;testis: 18.3 lung: 1.1 Not detected +SUN5 dJ726C3.1, SPAG4L, TSARG4 ENSG00000167098 Sad1 and UNC84 domain containing 5 20 32983773-33004433 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048529 Enhanced Not detected Tissue enriched 411 testis: 41.0 all non-specific tissues: 0.0 Not detected +SAMD14 FLJ36890 ENSG00000167100 Sterile alpha motif domain containing 14 17 50110040-50129882 Predicted intracellular proteins Evidence at protein level HPA051916 Uncertain Approved Nucleus
Nucleoli fibrillar center Tissue enhanced Tissue enhanced cerebral cortex: 6.2 testis: 1.8 Cell line enhanced HDLM-2: 12.8;HEL: 7.8;HMC-1: 24.7;SH-SY5Y: 14.0 +PIP5KL1 bA203J24.5, MGC46424 ENSG00000167103 Phosphatidylinositol-4-phosphate 5-kinase like 1 9 127920879-127930797 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056240 Uncertain Supported Cytosol Mixed Tissue enhanced parathyroid gland: 3.8 skin: 2.2 Cell line enhanced Karpas-707: 32.1;RPMI-8226: 21.0 +BPIFB6 BPIL3, LPLUNC6 ENSG00000167104 BPI fold containing family B member 6 20 33031648-33044047 Predicted secreted proteins Evidence at protein level HPA043057 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +TMEM92 FLJ33318 ENSG00000167105 Transmembrane protein 92 17 50271406-50281485 Predicted membrane proteins Evidence at protein level HPA063009, HPA069820 Approved Supported Nucleoplasm Renal cancer:1.14e-6 (unfavourable), Head and neck cancer:8.35e-4 (unfavourable) Mixed Tissue enhanced duodenum: 40.2;small intestine: 50.6 gallbladder: 21.8 Cell line enhanced A549: 16.5;CACO-2: 25.7;CAPAN-2: 25.7;EFO-21: 56.2 +FAM102A bA203J24.7, C9orf132, Eeig1, SYM-3A ENSG00000167106 Family with sequence similarity 102 member A 9 127940579-127980513 Predicted intracellular proteins Evidence at protein level HPA036030 Approved Cytosol Expressed in all Mixed stomach: 100.1 Expressed in all +ACSF2 ACSMW, FLJ20920 ENSG00000167107 Acyl-CoA synthetase family member 2 17 50426158-50474845 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA024693 Enhanced Approved Nucleoplasm
Microtubules
Cytosol Renal cancer:2.17e-4 (unfavourable), Urothelial cancer:2.41e-4 (favourable) Expressed in all Tissue enhanced kidney: 136.9 thyroid gland: 68.6 Expressed in all +GOLGA2 GM130, golgin-95 ENSG00000167110 Golgin A2 9 128255829-128275995 Predicted intracellular proteins Evidence at protein level CAB015421, HPA021178, HPA021230, HPA021799 Enhanced Enhanced Golgi apparatus Renal cancer:9.77e-5 (favourable), Colorectal cancer:1.64e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 161.0 Expressed in all +TRUB2 CLONE24922 ENSG00000167112 TruB pseudouridine synthase family member 2 9 128305161-128322742 Predicted intracellular proteins Evidence at protein level HPA021211, HPA052190 Uncertain Supported Cytosol Renal cancer:5.57e-10 (favourable) Expressed in all Mixed cerebral cortex: 9.0 Expressed in all +COQ4 CGI-92 ENSG00000167113 Coenzyme Q4 9 128322536-128334072 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021406, HPA042945 Supported Supported Mitochondria Endometrial cancer:4.93e-6 (favourable), Renal cancer:5.76e-6 (favourable), Cervical cancer:2.97e-5 (favourable) Expressed in all Expressed in all fallopian tube: 64.9 Expressed in all +SLC27A4 ACSVL4, FATP4 ENSG00000167114 Solute carrier family 27 member 4 9 128340646-128361470 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA007293, CAB009771 Approved Supported Vesicles Renal cancer:2.61e-5 (favourable) Expressed in all Expressed in all duodenum: 72.1 Expressed in all +URM1 C9orf74, MGC2668 ENSG00000167118 Ubiquitin related modifier 1 9 128371319-128392016 Predicted intracellular proteins Evidence at protein level HPA053645, HPA065160 Approved Approved Nucleoplasm
Vesicles Renal cancer:7.43e-6 (favourable), Liver cancer:6.91e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 25.1 Expressed in all +CERCAM CEECAM1, CerCAM, GLT25D3 ENSG00000167123 Cerebral endothelial cell adhesion molecule 9 128411751-128437351 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021657, HPA051595 Uncertain Approved Nucleus
Nucleoli
Cell Junctions Renal cancer:3.33e-16 (unfavourable), Urothelial cancer:3.30e-5 (unfavourable), Ovarian cancer:5.22e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 155.6 Mixed +DOLPP1 LSFR2 ENSG00000167130 Dolichyldiphosphatase 1 9 129081100-129090438 Enzymes, Predicted membrane proteins Evidence at protein level HPA019179 Approved Approved Vesicles
Intermediate filaments Expressed in all Expressed in all duodenum: 25.8 Expressed in all +CCDC103 CILD17, FLJ13094, FLJ34211, PR46b ENSG00000167131 Coiled-coil domain containing 103 17 44899142-44905390 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043131 Approved Cytosol Not detected Group enriched 7 fallopian tube: 24.5;testis: 27.0 thyroid gland: 3.6 Cell line enhanced A549: 10.3;U-87 MG: 9.5 +ENDOG ENSG00000167136 Endonuclease G 9 128818474-128822677 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA021335, HPA021830 Approved Renal cancer:1.06e-7 (favourable), Endometrial cancer:5.12e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 45.8 Expressed in all +TBC1D21 MGC34741, MgcRabGAP ENSG00000167139 TBC1 domain family member 21 15 73873608-73889214 Predicted intracellular proteins Evidence at protein level HPA043319 Enhanced Supported Not detected Tissue enriched 621 testis: 62.0 all non-specific tissues: 0.0 Not detected +PRRX2 PMX2, PRX2 ENSG00000167157 Paired related homeobox 2 9 129665641-129722674 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA006607, HPA026808 Approved Approved Nucleoplasm
Nuclear bodies Mixed Tissue enhanced cervix, uterine: 9.9;skin: 10.7 testis: 6.3 Cell line enhanced BJ: 24.1;BJ hTERT+: 16.5;fHDF/TERT166: 32.1;U-2197: 31.5 +UGT1A6 GNT1, HLUGP, UGT1F ENSG00000167165 UDP glucuronosyltransferase family 1 member A6 2 233691607-233773300 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009819, HPA054065 Enhanced Liver cancer:2.89e-6 (unfavourable) Tissue enhanced Group enriched 6 kidney: 75.4;liver: 72.4;urinary bladder: 107.9 esophagus: 15.2 Cell line enhanced CACO-2: 44.4;EFO-21: 75.2;HaCaT: 258.5;RT4: 119.0 +C15orf39 DKFZP434H132, FLJ46337 ENSG00000167173 Chromosome 15 open reading frame 39 15 75195643-75212169 Predicted intracellular proteins Evidence at protein level HPA039961, HPA041907 Uncertain Enhanced Cytosol Renal cancer:3.05e-4 (unfavourable), Testis cancer:6.02e-4 (unfavourable), Melanoma:7.94e-4 (favourable) Expressed in all Tissue enhanced testis: 123.7 bone marrow: 39.1 Expressed in all +ISLR2 KIAA1465 ENSG00000167178 Immunoglobulin superfamily containing leucine rich repeat 2 15 74100311-74138540 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012930, HPA067333 Uncertain Mixed Group enriched 5 cerebral cortex: 31.1;testis: 14.8 endometrium: 4.5 Group enriched 13 SCLC-21H: 68.2;SH-SY5Y: 91.6 +SP2 KIAA0048 ENSG00000167182 Sp2 transcription factor 17 47896150-47928957 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003357, CAB010245 Supported Enhanced Nucleoplasm
Vesicles Renal cancer:1.82e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 40.3 Expressed in all +PRR15L ATAD4, MGC11242 ENSG00000167183 Proline rich 15 like 17 47951967-47957878 Predicted intracellular proteins Evidence at protein level HPA022918 Approved Approved Cytosol Renal cancer:6.29e-13 (favourable), Stomach cancer:1.69e-5 (favourable) Mixed Tissue enhanced duodenum: 180.5 small intestine: 141.6 Cell line enhanced HaCaT: 18.3;MCF7: 15.0;SCLC-21H: 13.8;SK-BR-3: 26.8;T-47d: 22.7 +COQ7 CAT5, CLK-1 ENSG00000167186 Coenzyme Q7, hydroxylase 16 19067599-19080095 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067252, HPA071922 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:8.23e-12 (favourable) Expressed in all Expressed in all parathyroid gland: 39.2 Expressed in all +GPRC5B RAIG-2 ENSG00000167191 G protein-coupled receptor class C group 5 member B 16 19856691-19886167 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015247 Enhanced Supported Nucleus
Nucleoli
Vesicles Colorectal cancer:9.27e-5 (unfavourable), Renal cancer:6.30e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 308.3 testis: 66.2 Cell line enhanced EFO-21: 84.6;HHSteC: 50.7 +CRK ENSG00000167193 CRK proto-oncogene, adaptor protein 17 1420689-1463162 Predicted intracellular proteins Evidence at protein level CAB010485, HPA068087 Approved Approved Plasma membrane Expressed in all Expressed in all thyroid gland: 61.0 Expressed in all +C16orf92 FLJ25404 ENSG00000167194 Chromosome 16 open reading frame 92 16 30023334-30027736 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 7 testis: 22.9 cerebral cortex: 3.4 Cell line enhanced RPMI-8226: 1.7;SCLC-21H: 9.5;SH-SY5Y: 1.9 +GOLGA6C ENSG00000167195 Golgin A6 family member C 15 75258599-75270199 Predicted intracellular proteins Evidence at protein level HPA044978, HPA050087 Supported Not detected Tissue enriched 55 testis: 10.5 epididymis,liver,skeletal muscle: 0.1 Not detected +FBXO22 FBX22, FISTC1 ENSG00000167196 F-box protein 22 15 75903859-75942510 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all testis: 15.1 Expressed in all +TBC1D2B KIAA1055 ENSG00000167202 TBC1 domain family member 2B 15 77984036-78077724 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041833, HPA048174, HPA052663 Approved Supported Cytosol Expressed in all Expressed in all ovary: 57.3 Expressed in all +NOD2 BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, PSORAS1 ENSG00000167207 Nucleotide binding oligomerization domain containing 2 16 50693603-50733077 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041985, HPA054494 Enhanced Approved Golgi apparatus
Cytosol Mixed Mixed skin: 11.2 Cell line enhanced HMC-1: 10.3;T-47d: 5.3;THP-1: 4.8;U-266/70: 12.4;U-266/84: 5.1 +SNX20 SLIC-1, SLIC1 ENSG00000167208 Sorting nexin 20 16 50666300-50681353 Predicted intracellular proteins Evidence at protein level HPA043649 Uncertain Uncertain Nucleoplasm Renal cancer:6.00e-6 (unfavourable), Head and neck cancer:6.56e-4 (favourable), Cervical cancer:9.07e-4 (favourable) Mixed Tissue enhanced lymph node: 31.5 appendix: 26.4 Cell line enhanced HDLM-2: 27.0;HMC-1: 67.9;NB-4: 29.9;U-266/70: 19.2;U-937: 21.8 +LOXHD1 DFNB77, FLJ32670, LH2D1 ENSG00000167210 Lipoxygenase homology domains 1 18 46476972-46657033 Disease related genes, Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 9 epididymis: 8.3;testis: 41.3 fallopian tube: 2.6 Not detected +KATNAL2 DKFZP667C165, MGC33211 ENSG00000167216 Katanin catalytic subunit A1 like 2 18 46917492-47102243 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040712, HPA042029 Approved Approved Nucleoplasm
Intermediate filaments Renal cancer:1.24e-7 (favourable) Mixed Tissue enhanced parathyroid gland: 45.1;testis: 32.6 thyroid gland: 24.4 Mixed +HDHD2 DKFZP564D1378 ENSG00000167220 Haloacid dehalogenase like hydrolase domain containing 2 18 47107403-47150520 Predicted intracellular proteins Evidence at protein level HPA040697, CAB045978, HPA059818 Approved Approved Vesicles Renal cancer:3.52e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 47.9 Expressed in all +ZNF91 HPF7, HTF10 ENSG00000167232 Zinc finger protein 91 19 23304991-23395560 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Urothelial cancer:3.48e-4 (favourable), Renal cancer:7.58e-4 (favourable) Expressed in all Mixed thyroid gland: 17.6 Mixed +IGF2 C11orf43, FLJ44734, IGF-II ENSG00000167244 Insulin like growth factor 2 11 2129112-2141238 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007556, HPA007993 Enhanced Approved Nucleoplasm
Vesicles Liver cancer:7.12e-4 (favourable) Group enriched Tissue enriched 18 placenta: 3962.9 fallopian tube: 217.6 Cell line enhanced CACO-2: 711.5;Hep G2: 406.1;LHCN-M2: 277.7;RH-30: 396.9;SH-SY5Y: 525.9 +RNF214 DKFZp547C195 ENSG00000167257 Ring finger protein 214 11 117232625-117286445 Predicted intracellular proteins Evidence at protein level HPA039332 Approved Approved Golgi apparatus
Cytosol Liver cancer:6.03e-5 (unfavourable) Expressed in all Expressed in all testis: 33.4 Expressed in all +CDK12 CRK7, CRKR, CRKRS, KIAA0904 ENSG00000167258 Cyclin dependent kinase 12 17 39461511-39564907 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA008038 Supported Supported Nucleus Expressed in all Expressed in all testis: 33.8 Expressed in all +DPEP2 ENSG00000167261 Dipeptidase 2 16 67987394-68000586 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035644 Approved Testis cancer:8.47e-4 (unfavourable) Mixed Tissue enhanced spleen: 38.7 lung: 27.9 Cell line enhanced HEL: 3.7;HMC-1: 16.1;U-937: 4.9 +DUS2 DUS2L, FLJ20399, SMM1 ENSG00000167264 Dihydrouridine synthase 2 16 67987746-68079320 Predicted intracellular proteins Evidence at protein level HPA042560, HPA043528 Enhanced Enhanced Cytosol Renal cancer:3.50e-5 (favourable) Expressed in all Mixed testis: 39.2 Expressed in all +POP5 ENSG00000167272 POP5 homolog, ribonuclease P/MRP subunit 12 120578764-120581398 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047598, HPA069204 Approved Approved Nucleus
Nucleoli Cervical cancer:2.68e-5 (favourable), Renal cancer:4.85e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 51.8 Expressed in all +ENGASE FLJ21865 ENSG00000167280 Endo-beta-N-acetylglucosaminidase 17 79074939-79088599 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021551 Approved Approved Centrosome
Cytosol Renal cancer:8.97e-6 (unfavourable), Urothelial cancer:8.73e-5 (favourable), Pancreatic cancer:2.60e-4 (favourable) Expressed in all Expressed in all spleen: 28.1 Mixed +RBFOX3 FOX-3, HRNBP3, NeuN ENSG00000167281 RNA binding protein, fox-1 homolog 3 17 79089345-79516148 Predicted intracellular proteins Evidence at protein level HPA030790, CAB078782 Enhanced Approved Supported Nucleoplasm Tissue enhanced Tissue enhanced cerebral cortex: 62.3;seminal vesicle: 33.2 prostate: 24.1 Group enriched 7 A549: 14.1;NTERA-2: 13.9;SCLC-21H: 26.0;U-2 OS: 10.8 +ATP5L ATP5JG ENSG00000167283 ATP synthase, H+ transporting, mitochondrial Fo complex subunit G 11 118401154-118431496 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044629 Approved Supported Mitochondria Renal cancer:4.09e-5 (favourable) Expressed in all Expressed in all heart muscle: 117.0 Expressed in all +CD3D T3D ENSG00000167286 CD3d molecule 11 118338954-118342744 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB013055 Enhanced Endometrial cancer:1.73e-7 (favourable), Renal cancer:3.07e-5 (unfavourable), Cervical cancer:8.46e-5 (favourable), Head and neck cancer:1.70e-4 (favourable), Breast cancer:3.00e-4 (favourable), Urothelial cancer:6.16e-4 (favourable) Expressed in all Tissue enhanced lymph node: 199.3;tonsil: 119.1 appendix: 86.9 Cell line enriched 7 MOLT-4: 903.0 +TBC1D16 FLJ20748, MGC25062 ENSG00000167291 TBC1 domain family member 16 17 79932343-80035848 Predicted intracellular proteins Evidence at protein level HPA024482, HPA065839 Approved Approved Intermediate filaments Expressed in all Mixed adipose tissue: 40.7 Cell line enhanced SK-MEL-30: 155.6 +TEPSIN C17orf56, ENTHD2, FLJ31528 ENSG00000167302 TEPSIN, adaptor related protein complex 4 accessory protein 17 81228277-81239091 Predicted intracellular proteins Evidence at protein level HPA063410 Supported Nuclear membrane
Nuclear speckles
Golgi apparatus Renal cancer:7.31e-8 (unfavourable), Pancreatic cancer:6.95e-4 (favourable), Head and neck cancer:9.96e-4 (favourable) Expressed in all Expressed in all spleen: 15.8 Expressed in all +MYO5B KIAA1119 ENSG00000167306 Myosin VB 18 49822813-50195093 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040593, HPA040902, HPA069773 Enhanced Approved Plasma membrane Renal cancer:1.45e-11 (favourable), Pancreatic cancer:2.26e-5 (unfavourable) Expressed in all Mixed small intestine: 67.6 Cell line enhanced HaCaT: 88.6;RH-30: 147.5 +ART5 ENSG00000167311 ADP-ribosyltransferase 5 11 3638503-3642316 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA041637, HPA044099 Uncertain Renal cancer:1.85e-4 (favourable) Tissue enhanced Tissue enhanced ovary: 10.2;testis: 22.6 endometrium: 5.1 Cell line enhanced BEWO: 2.9;HEK 293: 1.9;U-2 OS: 2.1 +ACAA2 DSAEC ENSG00000167315 Acetyl-CoA acyltransferase 2 18 49782167-49813960 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042303 Enhanced Supported Mitochondria Renal cancer:1.36e-10 (favourable), Endometrial cancer:8.53e-4 (unfavourable) Expressed in all Expressed in all liver: 509.5 Mixed +STIM1 D11S4896E, GOK ENSG00000167323 Stromal interaction molecule 1 11 3854527-4093210 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA011088, HPA012123, CAB037128, CAB037288 Enhanced Enhanced Endoplasmic reticulum Expressed in all Expressed in all parathyroid gland: 86.8 Expressed in all +RRM1 ENSG00000167325 Ribonucleotide reductase catalytic subunit M1 11 4094707-4138876 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022093, HPA057265, HPA064297 Enhanced Enhanced Cytosol Liver cancer:1.53e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 60.4 Expressed in all +OR51E2 PSGR ENSG00000167332 Olfactory receptor family 51 subfamily E member 2 11 4680171-4697854 Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enriched 8 prostate: 45.9 placenta: 5.8 Cell line enhanced ASC TERT1: 1.3 +TRIM68 FLJ10369, RNF137, SS-56 ENSG00000167333 Tripartite motif containing 68 11 4598672-4608259 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023455 Uncertain Supported Nucleus
Cytosol Renal cancer:4.14e-6 (favourable) Expressed in all Expressed in all thyroid gland: 16.0 Mixed +MMP26 endometase, MGC126590, MGC126592 ENSG00000167346 Matrix metallopeptidase 26 11 4704927-4992429 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at transcript level Group enriched Tissue enriched 63 endometrium: 23.9 prostate,testis: 0.3 Not detected +OR51I1 ENSG00000167359 Olfactory receptor family 51 subfamily I member 1 11 5440570-5441514 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected epididymis: 0.1 Not detected +OR51Q1 ENSG00000167360 Olfactory receptor family 51 subfamily Q member 1 (gene/pseudogene) 11 5422111-5423206 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA044998 Uncertain Not detected Not detected epididymis: 0.1 Cell line enriched 23 RT4: 2.2 +FN3K ENSG00000167363 Fructosamine 3 kinase 17 82735575-82751197 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059151, HPA061358 Enhanced Approved Mitochondria Renal cancer:1.39e-6 (favourable), Endometrial cancer:1.10e-4 (favourable), Pancreatic cancer:2.40e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 56.8 Cell line enhanced HAP1: 34.0;Hep G2: 42.8 +PRRT2 DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC ENSG00000167371 Proline rich transmembrane protein 2 16 29811382-29815892 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014447, HPA019203 Enhanced Supported Plasma membrane Tissue enhanced Tissue enhanced cerebral cortex: 98.1 ovary: 54.6 Cell line enhanced AF22: 26.4;REH: 19.4;U-138 MG: 18.0 +ZNF23 KOX16, Zfp612, ZNF359, ZNF612 ENSG00000167377 Zinc finger protein 23 16 71447597-71463095 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023534 Uncertain Approved Cytosol Not detected Mixed cerebral cortex: 12.0 Expressed in all +IRGQ FKSG27, IRGQ1 ENSG00000167378 Immunity related GTPase Q 19 43584369-43596135 Predicted intracellular proteins Evidence at protein level HPA043254, HPA050338 Enhanced Supported Vesicles Pancreatic cancer:3.57e-5 (favourable), Renal cancer:3.92e-4 (favourable), Cervical cancer:5.17e-4 (favourable), Liver cancer:9.60e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 7.2 Mixed +ZNF226 ENSG00000167380 Zinc finger protein 226 19 44165073-44178381 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006145, CAB034353 Uncertain Approved Nuclear bodies Urothelial cancer:2.37e-5 (favourable), Pancreatic cancer:8.34e-4 (favourable) Expressed in all Expressed in all thyroid gland: 39.9 Expressed in all +ZNF180 HHZ168 ENSG00000167384 Zinc finger protein 180 19 44474428-44500524 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028979, HPA028980 Uncertain Approved Nucleoplasm Expressed in all Mixed parathyroid gland: 12.3 Mixed +PPP2R3B PPP2R3L, PPP2R3LY, PR48 ENSG00000167393 Protein phosphatase 2 regulatory subunit B''beta X 333963-386955 Predicted intracellular proteins Evidence at protein level HPA074545 Uncertain Endoplasmic reticulum Urothelial cancer:1.90e-5 (favourable), Pancreatic cancer:2.92e-5 (favourable) Expressed in all Tissue enhanced skeletal muscle: 14.7 heart muscle: 4.6 Cell line enhanced PC-3: 20.0;U-698: 23.8 +ZNF668 FLJ13479 ENSG00000167394 Zinc finger protein 668 16 31060843-31074320 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043048 Uncertain Approved Nucleus
Nucleoli Prostate cancer:6.24e-4 (unfavourable) Expressed in all Mixed testis: 6.9 Expressed in all +ZNF646 KIAA0296 ENSG00000167395 Zinc finger protein 646 16 31074422-31084196 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042364, HPA066468 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.28e-6 (unfavourable) Expressed in all Tissue enhanced testis: 34.3 spleen: 10.8 Expressed in all +VKORC1 VKCFD2 ENSG00000167397 Vitamin K epoxide reductase complex subunit 1 16 31090842-31095980 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA042720 Approved Supported Endoplasmic reticulum Renal cancer:2.09e-10 (unfavourable) Expressed in all Expressed in all liver: 141.4 Expressed in all +GNG8 ENSG00000167414 G protein subunit gamma 8 19 46634076-46634685 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Head and neck cancer:2.14e-5 (favourable) Tissue enhanced Tissue enhanced adrenal gland: 29.3 cerebral cortex: 10.2 Group enriched 10 SCLC-21H: 310.9;SH-SY5Y: 1226.5 +LPO SPO ENSG00000167419 Lactoperoxidase 17 58218548-58268518 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028688 Enhanced Supported Not detected Tissue enriched 221 salivary gland: 372.8 testis: 1.6 Cell line enriched 7 THP-1: 6.2 +CA4 CAIV, Car4, RP17 ENSG00000167434 Carbonic anhydrase 4 17 60149936-60170899 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011089, HPA017258 Enhanced Supported Vesicles Mixed Tissue enhanced colon: 253.5;rectum: 180.9 adipose tissue: 88.7 Not detected +SMG8 C17orf71, FLJ10587, FLJ23205 ENSG00000167447 SMG8, nonsense mediated mRNA decay factor 17 59209400-59215247 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024841 Approved Approved Nucleoplasm Liver cancer:3.72e-5 (unfavourable) Expressed in all Expressed in all testis: 13.9 Expressed in all +TPM4 ENSG00000167460 Tropomyosin 4 19 16067021-16103005 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004685, HPA047089, HPA053624 Approved Approved Actin filaments
Cytosol Renal cancer:1.26e-10 (unfavourable), Pancreatic cancer:3.07e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 814.8 Expressed in all +RAB8A MEL, RAB8 ENSG00000167461 RAB8A, member RAS oncogene family 19 16111629-16134234 Predicted intracellular proteins Evidence at protein level HPA041945 Supported Nucleus
Plasma membrane Renal cancer:6.56e-5 (unfavourable), Thyroid cancer:1.71e-4 (favourable) Expressed in all Expressed in all small intestine: 64.5 Expressed in all +GPX4 MCSP, PHGPx ENSG00000167468 Glutathione peroxidase 4 19 1103926-1106791 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB008630, HPA047224, HPA058546 Enhanced Supported Nucleoplasm
Mitochondria Endometrial cancer:1.84e-5 (favourable), Cervical cancer:7.18e-4 (favourable), Pancreatic cancer:7.72e-4 (favourable), Renal cancer:8.61e-4 (favourable) Expressed in all Expressed in all testis: 1140.7 Expressed in all +MIDN ENSG00000167470 Midnolin 19 1248553-1259140 Predicted intracellular proteins Evidence at protein level HPA042018, HPA049432 Uncertain Approved Nucleoplasm Expressed in all Expressed in all bone marrow: 51.5 Expressed in all +JSRP1 FLJ32416, JP-45 ENSG00000167476 Junctional sarcoplasmic reticulum protein 1 19 2252252-2269759 Predicted intracellular proteins Evidence at protein level HPA044741 Enhanced Approved Endoplasmic reticulum Tissue enhanced Tissue enriched 39 skeletal muscle: 116.2 duodenum: 2.9 Cell line enhanced Karpas-707: 117.9;RPMI-8226: 73.9;U-266/70: 338.6 +FAM129C BCNP1, FLJ39802 ENSG00000167483 Family with sequence similarity 129 member C 19 17523301-17553839 Predicted intracellular proteins Evidence at protein level HPA043277 Approved Mixed Group enriched 15 appendix: 13.9;bone marrow: 11.3;lymph node: 28.2;spleen: 36.9;tonsil: 9.4 gallbladder: 1.3 Group enriched 20 Daudi: 35.8;REH: 23.1;U-698: 21.5 +KLHL26 ENSG00000167487 Kelch like family member 26 19 18636965-18671714 Predicted intracellular proteins Evidence at protein level HPA023074 Uncertain Renal cancer:1.25e-6 (favourable), Breast cancer:5.01e-4 (favourable) Expressed in all Mixed cerebral cortex: 11.2 Mixed +GATAD2A p66alpha ENSG00000167491 GATA zinc finger domain containing 2A 19 19385826-19508931 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006759, HPA024373 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all testis: 64.1 Expressed in all +MVD MPD ENSG00000167508 Mevalonate diphosphate decarboxylase 16 88651935-88663161 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041404, HPA048250 Uncertain Approved Cell Junctions
Cytosol Endometrial cancer:2.17e-4 (favourable) Expressed in all Expressed in all duodenum: 33.9 Expressed in all +CDT1 DUP, RIS2 ENSG00000167513 Chromatin licensing and DNA replication factor 1 16 88803213-88809258 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA017224 Approved Supported Nucleus
Nuclear bodies Liver cancer:2.12e-6 (unfavourable), Renal cancer:2.69e-6 (unfavourable) Expressed in all Tissue enhanced bone marrow: 20.4 lymph node: 4.7 Mixed +TRAPPC2L HSPC176 ENSG00000167515 Trafficking protein particle complex 2 like 16 88856220-88862686 Predicted intracellular proteins Evidence at protein level HPA041714 Approved Supported Vesicles
Cytosol Endometrial cancer:3.75e-4 (favourable) Expressed in all Expressed in all adrenal gland: 91.5 Expressed in all +ANKRD11 LZ16, T13 ENSG00000167522 Ankyrin repeat domain 11 16 89267627-89490561 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB019288, HPA041593, HPA049470 Approved Supported Nucleoplasm
Cytosol Liver cancer:6.39e-4 (unfavourable), Prostate cancer:7.67e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 24.4 Expressed in all +SPATA33 C16orf55, FLJ31606 ENSG00000167523 Spermatogenesis associated 33 16 89657802-89671272 Predicted intracellular proteins Evidence at protein level HPA045648, HPA073096 Enhanced Approved Nucleoplasm
Vesicles Cervical cancer:1.06e-4 (favourable) Expressed in all Tissue enhanced testis: 77.2 fallopian tube: 25.6 Expressed in all +SGK494 ENSG00000167524 Uncharacterized serine/threonine-protein kinase SgK494 17 28607964-28614200 Predicted intracellular proteins Evidence at protein level HPA046590 Uncertain Approved Nucleoplasm
Vesicles
Plasma membrane Mixed Mixed testis: 10.5 Mixed +PROCA1 MGC39650 ENSG00000167525 Protein interacting with cyclin A1 17 28703197-28711854 Predicted intracellular proteins Evidence at transcript level HPA023648 Approved Mixed Tissue enriched 20 testis: 139.5 spleen: 6.9 Cell line enhanced REH: 11.1 +RPL13 BBC1, D16S444E, L13 ENSG00000167526 Ribosomal protein L13 16 89560657-89566828 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA051702 Approved Enhanced Nucleoli
Endoplasmic reticulum
Cytosol Endometrial cancer:6.26e-4 (favourable), Renal cancer:6.64e-4 (unfavourable) Expressed in all Expressed in all ovary: 3872.9 Expressed in all +ZNF641 FLJ31295 ENSG00000167528 Zinc finger protein 641 12 48337180-48351414 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035189 Uncertain Supported Nucleoplasm Pancreatic cancer:8.30e-5 (favourable), Ovarian cancer:3.91e-4 (favourable) Expressed in all Expressed in all adrenal gland: 28.8 Expressed in all +LALBA LYZL7 ENSG00000167531 Lactalbumin alpha 12 48567684-48570066 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB026343, HPA029855, HPA029856 Supported Tissue enriched Tissue enriched 566 breast: 2476.8 testis: 4.3 Not detected +CACNB3 CACNLB3 ENSG00000167535 Calcium voltage-gated channel auxiliary subunit beta 3 12 48813794-48828941 FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA059515 Approved Golgi apparatus
Vesicles Mixed Mixed endometrium: 40.0 Cell line enhanced U-937: 85.2 +DHRS13 MGC23280, SDR7C5 ENSG00000167536 Dehydrogenase/reductase 13 17 28897781-28903071 Predicted intracellular proteins Evidence at protein level HPA022991 Uncertain Approved Vesicles Liver cancer:3.39e-6 (unfavourable) Expressed in all Mixed bone marrow: 25.2 Mixed +TP53I13 DSCP1 ENSG00000167543 Tumor protein p53 inducible protein 13 17 29566052-29573157 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Renal cancer:2.10e-6 (unfavourable), Pancreatic cancer:3.13e-5 (favourable) Expressed in all Expressed in all adipose tissue: 53.3 Expressed in all +KMT2D ALR, CAGL114, MLL2, MLL4, TNRC21 ENSG00000167548 Lysine methyltransferase 2D 12 49018975-49059774 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035977 Approved Approved Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 46.6 Expressed in all +CORO6 FLJ14871 ENSG00000167549 Coronin 6 17 29614756-29622907 Predicted intracellular proteins Evidence at protein level HPA021556 Supported Golgi apparatus Renal cancer:9.61e-7 (unfavourable) Tissue enhanced Tissue enhanced skeletal muscle: 127.5 heart muscle: 46.5 Cell line enhanced REH: 15.0;RH-30: 17.3;SH-SY5Y: 23.2 +RHEBL1 FLJ25797, MGC34869 ENSG00000167550 Ras homolog enriched in brain like 1 12 49064685-49070025 Predicted intracellular proteins Evidence at protein level HPA053111, HPA061001 Uncertain Uncertain Nucleus
Centrosome Mixed Mixed fallopian tube,lymph node: 3.8 Cell line enhanced HDLM-2: 26.3;U-266/84: 40.4 +TUBA1A B-ALPHA-1, FLJ25113, TUBA3 ENSG00000167552 Tubulin alpha 1a 12 49184796-49189324 Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB008686, HPA039247, HPA043684, HPA063394 Enhanced Enhanced Microtubules Renal cancer:2.90e-4 (unfavourable) Tissue enriched Expressed in all cerebral cortex: 1373.1 Expressed in all +TUBA1C bcm948, MGC10851, MGC14580, TUBA6 ENSG00000167553 Tubulin alpha 1c 12 49188736-49274603 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039247, HPA043684, HPA063394 Supported Supported Microtubules Liver cancer:8.48e-8 (unfavourable), Renal cancer:6.26e-7 (unfavourable), Pancreatic cancer:5.64e-6 (unfavourable), Colorectal cancer:7.37e-5 (favourable), Breast cancer:2.90e-4 (unfavourable), Lung cancer:6.85e-4 (unfavourable) Expressed in all Expressed in all esophagus: 311.2 Expressed in all +ZNF610 FLJ36040 ENSG00000167554 Zinc finger protein 610 19 52336245-52367778 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055771, HPA078134 Enhanced Approved Nucleus Renal cancer:1.05e-7 (favourable), Ovarian cancer:3.38e-4 (favourable) Mixed Tissue enhanced testis: 22.0 ovary: 10.4 Mixed +ZNF528 KIAA1827 ENSG00000167555 Zinc finger protein 528 19 52397849-52418412 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA065435 Approved Nuclear speckles
Cytosol Expressed in all Expressed in all thyroid gland: 31.1 Mixed +ZNF701 FLJ10891 ENSG00000167562 Zinc finger protein 701 19 52555457-52587174 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005532 Uncertain Approved Nucleoplasm
Microtubule organizing center Urothelial cancer:4.89e-5 (favourable) Mixed Expressed in all thyroid gland: 16.2 Mixed +SERTAD3 RBT1 ENSG00000167565 SERTA domain containing 3 19 40440844-40444705 Predicted intracellular proteins Evidence at protein level HPA068262 Supported Nucleoli Expressed in all Expressed in all prostate: 40.4 Expressed in all +NCKAP5L KIAA1602 ENSG00000167566 NCK associated protein 5 like 12 49791146-49828750 Predicted intracellular proteins Evidence at protein level HPA041034 Approved Approved Golgi apparatus Renal cancer:1.16e-5 (unfavourable), Liver cancer:2.07e-4 (unfavourable), Pancreatic cancer:4.87e-4 (favourable) Expressed in all Expressed in all placenta: 12.9 Mixed +RAB4B FLJ78649, MGC52123 ENSG00000167578 RAB4B, member RAS oncogene family 19 40778216-40796938 Predicted intracellular proteins Evidence at protein level Urothelial cancer:1.99e-5 (favourable), Renal cancer:1.28e-4 (unfavourable), Pancreatic cancer:2.08e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 56.1 Expressed in all +AQP2 ENSG00000167580 Aquaporin 2 12 49950741-49958881 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046834 Enhanced Group enriched Group enriched 132 kidney: 435.9;seminal vesicle: 302.5 testis: 2.8 Cell line enhanced EFO-21: 3.0;HMC-1: 1.7 +GPD1 ENSG00000167588 Glycerol-3-phosphate dehydrogenase 1 12 50103819-50111319 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA044620 Enhanced Mixed Tissue enhanced adipose tissue: 636.1;skeletal muscle: 195.7 kidney: 148.1 Cell line enhanced ASC diff: 86.3;CACO-2: 22.1;Hep G2: 17.0;RPMI-8226: 20.7 +PROSER3 C19orf55, FLJ30657 ENSG00000167595 Proline and serine rich 3 19 35758143-35771028 Predicted intracellular proteins Evidence at protein level HPA058492 Approved Approved Golgi apparatus Renal cancer:3.74e-7 (unfavourable) Expressed in all Mixed testis: 14.1 Mixed +CYP2S1 ENSG00000167600 Cytochrome P450 family 2 subfamily S member 1 19 41193049-41207539 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA049227, HPA069248 Approved Approved Endoplasmic reticulum Renal cancer:1.60e-6 (unfavourable) Expressed in all Tissue enhanced duodenum: 96.7;small intestine: 68.6;stomach: 111.7 colon: 25.9 Cell line enhanced A549: 83.4;CACO-2: 39.6;HaCaT: 43.5;NTERA-2: 68.5 +AXL ARK, JTK11, Tyro7, UFO ENSG00000167601 AXL receptor tyrosine kinase 19 41219203-41261766 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB032501, HPA037422, HPA037423 Uncertain Renal cancer:2.53e-7 (unfavourable) Expressed in all Expressed in all smooth muscle: 54.6 Mixed +NFKBID IkappaBNS, TA-NFKBH ENSG00000167604 NFKB inhibitor delta 19 35887653-35902303 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043573 Approved Mitochondria Urothelial cancer:8.34e-6 (favourable), Head and neck cancer:5.43e-4 (favourable), Breast cancer:6.01e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 9.8 appendix: 5.9 Mixed +TMC4 ENSG00000167608 Transmembrane channel like 4 19 54160108-54173250 Predicted membrane proteins Evidence at protein level HPA048635 Approved Renal cancer:1.54e-8 (favourable) Expressed in all Tissue enhanced duodenum: 30.8 small intestine: 22.1 Cell line enriched 7 T-47d: 27.9 +ANKRD33 C12orf7, DKFZp686O1689, PANKY ENSG00000167612 Ankyrin repeat domain 33 12 51887960-51891664 Predicted intracellular proteins Evidence at transcript level HPA040013, HPA058753 Uncertain Not detected Not detected placenta: 0.5 Not detected +LAIR1 CD305 ENSG00000167613 Leukocyte associated immunoglobulin like receptor 1 19 54351384-54370558 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011155 Enhanced Supported Plasma membrane Renal cancer:5.01e-5 (unfavourable) Expressed in all Tissue enhanced lymph node: 7.1 appendix: 4.2 Cell line enhanced HMC-1: 6.6;Karpas-707: 14.1;THP-1: 15.4 +TTYH1 ENSG00000167614 Tweety family member 1 19 54415219-54436900 Predicted membrane proteins, Transporters Evidence at protein level HPA023617, HPA050655 Approved Breast cancer:3.64e-4 (favourable) Tissue enriched Tissue enriched 27 cerebral cortex: 57.7 fallopian tube,testis: 2.1 Group enriched 6 AF22: 5.8;AN3-CA: 17.4;U-2 OS: 7.0 +LENG8 KIAA1932, MGC40108, pp13842 ENSG00000167615 Leukocyte receptor cluster member 8 19 54448887-54462037 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042004, HPA042056, HPA061571 Uncertain Supported Nucleus Renal cancer:3.30e-7 (unfavourable), Urothelial cancer:2.73e-6 (favourable), Head and neck cancer:7.59e-4 (favourable) Expressed in all Expressed in all spleen: 165.7 Expressed in all +CDC42EP5 Borg3, CEP5 ENSG00000167617 CDC42 effector protein 5 19 54465026-54473264 Predicted intracellular proteins Evidence at protein level HPA043449 Approved Renal cancer:2.79e-5 (unfavourable), Urothelial cancer:1.36e-4 (favourable) Expressed in all Tissue enhanced colon: 3.1;prostate: 2.4 adipose tissue: 0.9 Not detected +LAIR2 CD306 ENSG00000167618 Leukocyte associated immunoglobulin like receptor 2 19 54497879-54510687 CD markers, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced lymph node: 1.4 spleen: 0.8 Cell line enhanced BEWO: 2.2 +TMEM145 FLJ90805 ENSG00000167619 Transmembrane protein 145 19 42313325-42325062 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060462 Enhanced Approved Vesicles Tissue enhanced Tissue enriched 6 cerebral cortex: 38.3 adrenal gland: 5.9 Cell line enhanced SCLC-21H: 32.9;SH-SY5Y: 14.2 +ZNF526 KIAA1951, MGC4267 ENSG00000167625 Zinc finger protein 526 19 42220271-42228201 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023070, HPA056609 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Expressed in all Mixed skin: 6.2 Expressed in all +TRAPPC9 IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120 ENSG00000167632 Trafficking protein particle complex 9 8 139730343-140458579 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026579 Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:5.11e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 49.7 Expressed in all +KIR3DL1 AMB11, CD158E1, CD158e1/2, CD158e2, cl-11, cl-2, KIR, nkat3, NKB1, NKB1B ENSG00000167633 Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 19 54816468-54830778 CD markers, Predicted membrane proteins Evidence at protein level Not detected Not detected bone marrow: 0.1 Not detected +NLRP7 CLR19.4, NALP7, NOD12, PAN7, PYPAF3 ENSG00000167634 NLR family pyrin domain containing 7 19 54923509-54966312 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051382 Uncertain Uncertain Golgi apparatus Tissue enriched Tissue enriched 14 testis: 2.8 duodenum: 0.2 Cell line enhanced BEWO: 1.8;U-266/84: 3.4 +ZNF146 OZF ENSG00000167635 Zinc finger protein 146 19 36214602-36238774 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003358 Supported Supported Nucleoli Expressed in all Expressed in all parathyroid gland: 63.2 Expressed in all +ZNF283 ENSG00000167637 Zinc finger protein 283 19 43827292-43852017 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA072977 Approved Nucleoplasm Mixed Mixed parathyroid gland: 10.2 Cell line enhanced U-2 OS: 25.1 +PPP1R14A CPI-17, PPP1INL ENSG00000167641 Protein phosphatase 1 regulatory inhibitor subunit 14A 19 38251237-38256591 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005044, CAB009803, HPA042097, HPA054534 Enhanced Supported Nucleoplasm
Nuclear bodies Renal cancer:1.25e-5 (unfavourable), Stomach cancer:7.12e-4 (unfavourable) Expressed in all Mixed seminal vesicle: 110.8 Cell line enhanced A549: 89.9;EFO-21: 78.3;K-562: 38.3 +SPINT2 HAI-2, Kop ENSG00000167642 Serine peptidase inhibitor, Kunitz type 2 19 38244035-38292614 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011101, CAB018969 Approved Uncertain Plasma membrane
Intermediate filaments
Cytosol Renal cancer:3.41e-4 (favourable) Expressed in all Mixed thyroid gland: 539.2 Cell line enhanced A-431: 736.5;CAPAN-2: 1060.7 +C19orf33 H2RSP, IMUP, IMUP-1, IMUP-2 ENSG00000167644 Chromosome 19 open reading frame 33 19 38304161-38305009 Predicted intracellular proteins Evidence at protein level HPA054406, HPA059696 Uncertain Supported Nucleus
Plasma membrane
Cytosol Pancreatic cancer:5.05e-4 (unfavourable), Lung cancer:5.42e-4 (unfavourable) Mixed Mixed esophagus: 177.8 Cell line enhanced A-431: 535.8;A549: 841.0;CAPAN-2: 498.9;PC-3: 484.7 +YIF1B FinGER8 ENSG00000167645 Yip1 interacting factor homolog B, membrane trafficking protein 19 38305104-38317273 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039328, HPA055257, HPA062675 Approved Approved Golgi apparatus
Vesicles Liver cancer:4.53e-5 (unfavourable), Pancreatic cancer:1.88e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 49.5 Expressed in all +DNAAF3 C19orf51, CILD2, FLJ36139, FLJ40069, PCD, PF22 ENSG00000167646 Dynein axonemal assembly factor 3 19 55158661-55166722 Predicted intracellular proteins Evidence at protein level HPA056220 Approved Nuclear bodies
Mitochondria Renal cancer:1.83e-5 (unfavourable) Mixed Group enriched 12 fallopian tube: 69.1;testis: 67.9 lung: 5.9 Cell line enhanced HEK 293: 24.3;HEL: 28.5;K-562: 22.5 +PSCA ENSG00000167653 Prostate stem cell antigen 8 142670308-142682724 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030783, HPA056418 Approved Supported Plasma membrane Pancreatic cancer:5.60e-5 (unfavourable) Tissue enriched Group enriched 8 prostate: 344.6;stomach: 1648.5;urinary bladder: 343.4 esophagus: 101.7 Cell line enhanced CAPAN-2: 18.6;HeLa: 27.5;RT4: 47.1 +ATCAY BNIP-H ENSG00000167654 ATCAY, caytaxin 19 3879864-3928079 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA017755 Enhanced Tissue enriched Tissue enriched 12 cerebral cortex: 108.9 adrenal gland: 8.8 Cell line enhanced NTERA-2: 7.2;SCLC-21H: 15.5;SH-SY5Y: 9.8 +LY6D E48 ENSG00000167656 Lymphocyte antigen 6 family member D 8 142784880-142786592 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA024755, HPA064317 Enhanced Pancreatic cancer:1.94e-6 (unfavourable), Renal cancer:1.20e-4 (unfavourable) Group enriched Group enriched 11 esophagus: 631.6;skin: 717.0 tonsil: 61.0 Cell line enriched 26 A-431: 128.0 +DAPK3 ZIP, ZIPK ENSG00000167657 Death associated protein kinase 3 19 3958453-3971123 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028569, HPA064809 Approved Approved Nucleus Endometrial cancer:2.01e-5 (favourable), Renal cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all endometrium: 76.3 Expressed in all +EEF2 EEF-2, EF2 ENSG00000167658 Eukaryotic translation elongation factor 2 19 3976056-3985469 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007795, HPA040534, HPA057351 Enhanced Enhanced Plasma membrane
Cytosol Endometrial cancer:1.81e-6 (favourable), Renal cancer:1.25e-5 (favourable) Expressed in all Expressed in all ovary: 1621.6 Expressed in all +TMIGD2 CD28H, IGPR-1, MGC23244 ENSG00000167664 Transmembrane and immunoglobulin domain containing 2 19 4292232-4302431 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011081 Approved Mixed Tissue enhanced lymph node: 7.4 appendix: 5.5 Cell line enhanced BEWO: 12.1;HEL: 26.9;MOLT-4: 21.9 +CHAF1A CAF-1, CAF1, CAF1B, CAF1P150, MGC71229, P150 ENSG00000167670 Chromatin assembly factor 1 subunit A 19 4402662-4445018 Predicted intracellular proteins Evidence at protein level CAB015186 Enhanced Supported Nucleus
Cytosol Stomach cancer:4.15e-6 (favourable), Cervical cancer:8.22e-5 (favourable) Expressed in all Mixed testis: 21.9 Expressed in all +UBXN6 UBXD1, UBXDC2 ENSG00000167671 UBX domain protein 6 19 4444999-4457822 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040906, HPA041313, HPA061872 Approved Approved Golgi apparatus
Cytosol Renal cancer:2.78e-5 (favourable), Endometrial cancer:5.68e-5 (favourable), Pancreatic cancer:6.95e-4 (favourable) Expressed in all Expressed in all testis: 138.8 Expressed in all +CTB-50L17.10 ENSG00000167674 Hepatoma-derived growth factor-related protein 2 19 4472287-4502211 Predicted intracellular proteins Evidence at protein level HPA042559, HPA044208 Enhanced Supported Nucleoplasm Pancreatic cancer:6.57e-4 (favourable) Expressed in all Expressed in all testis: 62.2 Expressed in all +PLIN4 KIAA1881, S3-12 ENSG00000167676 Perilipin 4 19 4502180-4518465 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044682, HPA054657 Enhanced Supported Vesicles
Lipid droplets
Plasma membrane
Cytosol Endometrial cancer:2.31e-4 (unfavourable), Colorectal cancer:8.31e-4 (unfavourable) Mixed Tissue enriched 14 adipose tissue: 812.2 skeletal muscle: 59.1 Cell line enriched 7 ASC diff: 171.0 +SEMA6B SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ ENSG00000167680 Semaphorin 6B 19 4542593-4559808 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB025157, HPA055778, HPA058523 Enhanced Renal cancer:3.29e-5 (unfavourable), Thyroid cancer:1.45e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 65.5 spleen: 24.5 Cell line enhanced Hep G2: 88.4;HMC-1: 180.6;HUVEC TERT2: 71.3;TIME: 88.7 +ZNF444 EZF2, FLJ11137, ZSCAN17 ENSG00000167685 Zinc finger protein 444 19 56132599-56160893 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056895, HPA065203 Approved Supported Nucleus
Nucleoli Urothelial cancer:1.87e-4 (favourable), Renal cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 27.8 Expressed in all +NXN FLJ12614, NRX ENSG00000167693 Nucleoredoxin 17 799313-979770 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023566 Approved Supported Golgi apparatus
Cytosol Expressed in all Mixed endometrium: 42.7 Mixed +FAM57A CT120, FLJ22282 ENSG00000167695 Family with sequence similarity 57 member A 17 732412-742972 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Endometrial cancer:3.53e-6 (favourable), Renal cancer:1.44e-4 (unfavourable) Expressed in all Tissue enhanced skin: 82.7 esophagus: 25.9 Expressed in all +GLOD4 C17orf25, CGI-150, HC71 ENSG00000167699 Glyoxalase domain containing 4 17 757097-783390 Predicted intracellular proteins Evidence at protein level HPA021623, HPA023246, HPA023248 Enhanced Approved Nucleus
Nucleoli
Cytosol Renal cancer:2.18e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 82.7 Expressed in all +MFSD3 ENSG00000167700 Major facilitator superfamily domain containing 3 8 144509074-144511213 Predicted membrane proteins Evidence at protein level HPA056013 Uncertain Approved Vesicles Renal cancer:5.44e-7 (favourable), Cervical cancer:5.08e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 14.5 Mixed +GPT ALT1, GPT1 ENSG00000167701 Glutamic--pyruvic transaminase 8 144502973-144507174 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031059, HPA031060, CAB032997, CAB032999 Enhanced Liver cancer:1.47e-5 (favourable), Renal cancer:2.19e-4 (favourable) Tissue enriched Mixed liver: 25.0 Mixed +KIFC2 ENSG00000167702 Kinesin family member C2 8 144466043-144474202 Predicted secreted proteins Evidence at protein level HPA029264 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all skin: 73.1 Mixed +SLC43A2 MGC34680 ENSG00000167703 Solute carrier family 43 member 2 17 1569267-1628886 Predicted membrane proteins, Transporters Evidence at protein level HPA021564 Enhanced Pancreatic cancer:1.05e-6 (favourable), Renal cancer:5.40e-5 (favourable) Expressed in all Tissue enhanced placenta: 31.7 appendix: 17.0 Cell line enhanced CACO-2: 14.8 +RILP FLJ31193 ENSG00000167705 Rab interacting lysosomal protein 17 1646145-1650077 Predicted intracellular proteins Evidence at protein level Renal cancer:8.51e-5 (favourable), Urothelial cancer:7.12e-4 (favourable), Breast cancer:7.97e-4 (favourable) Expressed in all Mixed skeletal muscle: 8.7 Cell line enhanced HEL: 16.7;HMC-1: 8.2 +SERPINF2 A2AP, AAP, ALPHA-2-PI, API, PLI ENSG00000167711 Serpin family F member 2 17 1742836-1755268 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001885, CAB024863 Approved Uncertain Nucleoplasm
Vesicles Liver cancer:2.26e-5 (favourable) Tissue enriched Tissue enhanced epididymis: 117.4;liver: 452.5 kidney: 63.3 Cell line enriched 24 Hep G2: 99.1 +WDR81 CAMRQ2, FLJ33817, PPP1R166, SORF-2 ENSG00000167716 WD repeat domain 81 17 1716523-1738599 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023044 Uncertain Approved Nucleoplasm Pancreatic cancer:3.30e-4 (favourable) Expressed in all Mixed ovary,spleen: 10.4 Mixed +SRR ILV1, ISO1 ENSG00000167720 Serine racemase 17 2303383-2325260 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007529, CAB015343 Approved Approved Vesicles Renal cancer:2.45e-6 (favourable), Endometrial cancer:6.20e-5 (favourable), Pancreatic cancer:8.16e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 25.5 Expressed in all +TSR1 FLJ10534 ENSG00000167721 TSR1, ribosome maturation factor 17 2322503-2337507 Predicted intracellular proteins Evidence at protein level HPA024434, HPA053087 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 28.8 Expressed in all +TRPV3 VRL3 ENSG00000167723 Transient receptor potential cation channel subfamily V member 3 17 3510502-3557995 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA069550 Approved Plasma membrane
Centrosome
Cytosol Mixed Tissue enhanced skin: 5.1;small intestine: 4.5 duodenum: 1.7 Cell line enhanced BEWO: 3.6;RH-30: 9.0;T-47d: 3.7 +HSD11B1L SCDR10, SDR26C2 ENSG00000167733 Hydroxysteroid 11-beta dehydrogenase 1 like 19 5680604-5688523 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA049078 Approved Vesicles Head and neck cancer:4.38e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 25.6 fallopian tube: 7.9 Cell line enhanced SH-SY5Y: 20.1 +CYB5D2 MGC32124 ENSG00000167740 Cytochrome b5 domain containing 2 17 4143168-4187310 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042299 Approved Approved Nuclear membrane
Nucleoli
Centrosome Renal cancer:2.03e-10 (favourable), Liver cancer:4.98e-6 (favourable), Pancreatic cancer:7.76e-5 (favourable), Endometrial cancer:6.19e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 51.8 Expressed in all +GGT6 FLJ90165 ENSG00000167741 Gamma-glutamyltransferase 6 17 4556927-4560818 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023362, HPA027213 Approved Renal cancer:9.42e-7 (favourable), Lung cancer:4.35e-4 (favourable) Mixed Mixed colon: 54.8 Group enriched 8 RT4: 48.3;SK-BR-3: 15.2;T-47d: 59.4 +C19orf48 MGC13170 ENSG00000167747 Chromosome 19 open reading frame 48 19 50797704-50804929 Predicted intracellular proteins Evidence at transcript level HPA042000 Uncertain Approved Plasma membrane Liver cancer:8.80e-5 (unfavourable) Expressed in all Expressed in all prostate: 84.5 Expressed in all +KLK1 Klk6 ENSG00000167748 Kallikrein 1 19 50819148-50823787 Enzymes, Predicted secreted proteins Evidence at protein level Group enriched Group enriched 36 pancreas: 1994.7;salivary gland: 2549.9 colon: 63.5 Cell line enriched 18 RPMI-8226: 26.9 +KLK4 EMSP, EMSP1, KLK-L1, PRSS17, PSTS ENSG00000167749 Kallikrein related peptidase 4 19 50906352-50910738 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051839 Enhanced Tissue enriched Tissue enriched 37 prostate: 406.5 skin: 10.8 Cell line enhanced CAPAN-2: 5.7;HaCaT: 7.0 +KLK2 ENSG00000167751 Kallikrein related peptidase 2 19 50861568-50880567 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000764 Supported Tissue enriched Tissue enriched 192 prostate: 867.2 testis: 4.5 Cell line enhanced NB-4: 3.6 +KLK5 KLK-L2, SCTE ENSG00000167754 Kallikrein related peptidase 5 19 50943303-50953093 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at protein level HPA014343, CAB025503, CAB026341 Enhanced Urothelial cancer:3.85e-6 (unfavourable), Endometrial cancer:2.33e-4 (unfavourable), Lung cancer:9.79e-4 (unfavourable) Tissue enhanced Tissue enriched 6 skin: 213.5 breast: 37.8 Group enriched 41 A-431: 414.4;HaCaT: 396.7 +KLK6 Bssp, Klk7, neurosin, PRSS18, PRSS9 ENSG00000167755 Kallikrein related peptidase 6 19 50958631-50969673 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051837 Supported Nucleoplasm
Nuclear membrane
Cytokinetic bridge Endometrial cancer:1.38e-5 (unfavourable), Urothelial cancer:1.27e-4 (unfavourable), Pancreatic cancer:7.82e-4 (unfavourable), Lung cancer:8.85e-4 (unfavourable) Tissue enhanced Group enriched 5 cerebral cortex: 78.6;esophagus: 63.0;fallopian tube: 44.9;tonsil: 31.3 kidney: 10.2 Group enriched 15 A-431: 496.5;CAPAN-2: 1158.9 +KLK11 PRSS20, TLSP ENSG00000167757 Kallikrein related peptidase 11 19 51022216-51028039 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026340 Approved Endometrial cancer:3.78e-4 (favourable), Pancreatic cancer:4.17e-4 (unfavourable) Mixed Tissue enhanced esophagus: 225.7;skin: 214.5 prostate: 104.9 Cell line enhanced CAPAN-2: 5.6;EFO-21: 12.3;HaCaT: 36.6 +KLK13 KLK-L4 ENSG00000167759 Kallikrein related peptidase 13 19 51056206-51065114 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at protein level HPA062136 Enhanced Tissue enhanced Tissue enriched 9 esophagus: 402.2 tonsil: 45.0 Cell line enriched 10 HaCaT: 16.8 +ZNF83 FLJ11015, HPF1, ZNF816B ENSG00000167766 Zinc finger protein 83 19 52594060-52690496 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA025970 Approved Approved Nucleoplasm Urothelial cancer:6.92e-6 (favourable), Renal cancer:3.13e-5 (unfavourable), Head and neck cancer:3.83e-4 (favourable), Ovarian cancer:9.06e-4 (favourable), Melanoma:9.20e-4 (unfavourable) Expressed in all Expressed in all epididymis: 111.9 Mixed +KRT80 KB20 ENSG00000167767 Keratin 80 12 52168996-52192000 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA077836, HPA077918 Enhanced Intermediate filaments Breast cancer:1.05e-4 (unfavourable) Mixed Tissue enhanced skin: 125.0 tonsil: 37.7 Cell line enhanced A-431: 176.4;MCF7: 219.4;U-2 OS: 184.3 +KRT1 EHK1, KRT1A ENSG00000167768 Keratin 1 12 52674736-52680407 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002153, HPA017917, HPA062908 Enhanced Group enriched Tissue enriched 25 skin: 15454.7 breast: 622.4 Group enriched 36 HaCaT: 84.1;hTCEpi: 28.5 +ACER1 ASAH3 ENSG00000167769 Alkaline ceramidase 1 19 6306142-6333629 Enzymes, Predicted membrane proteins Evidence at transcript level Group enriched Tissue enriched 6 skin: 67.8 esophagus: 11.4 Cell line enhanced T-47d: 2.7 +OTUB1 FLJ20113, FLJ40710 ENSG00000167770 OTU deubiquitinase, ubiquitin aldehyde binding 1 11 63985853-64001811 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039176, CAB072836 Approved Supported Approved Nucleus
Cytosol Head and neck cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 116.0 Expressed in all +RCOR2 ENSG00000167771 REST corepressor 2 11 63911221-63916844 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021638 Uncertain Approved Nucleus
Vesicles
Midbody Mixed Tissue enhanced cerebral cortex: 13.2 testis: 3.7 Cell line enhanced AF22: 39.9;NTERA-2: 52.3;SCLC-21H: 95.8;SH-SY5Y: 57.5 +ANGPTL4 ARP4, FIAF, HFARP, NL2, PGAR, pp1158 ENSG00000167772 Angiopoietin like 4 19 8363289-8374373 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007879, CAB033770 Approved Approved Nucleoplasm
Vesicles Renal cancer:1.34e-5 (unfavourable), Colorectal cancer:7.53e-4 (unfavourable), Lung cancer:9.50e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 78.7 liver: 43.2 Cell line enhanced HBEC3-KT: 161.5;TIME: 92.8;U-138 MG: 64.0 +CD320 8D6, 8D6A ENSG00000167775 CD320 molecule 19 8302127-8308356 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level HPA014500, HPA073489 Approved Approved Cytosol Liver cancer:4.02e-4 (unfavourable) Expressed in all Expressed in all epididymis: 77.2 Mixed +SPRYD3 FLJ14800 ENSG00000167778 SPRY domain containing 3 12 53064316-53079420 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039426, HPA039685 Enhanced Approved Nucleoplasm
Actin filaments
Cytosol Renal cancer:1.78e-15 (favourable), Head and neck cancer:9.46e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 144.9 Expressed in all +IGFBP6 ENSG00000167779 Insulin like growth factor binding protein 6 12 53097436-53102345 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA008005 Uncertain Glioma:6.66e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 72.2 cervix, uterine: 47.7 Cell line enhanced BJ: 290.6;HaCaT: 180.1;U-87 MG: 136.0 +SOAT2 ACAT2 ENSG00000167780 Sterol O-acyltransferase 2 12 53103518-53124538 Enzymes, Predicted membrane proteins Evidence at protein level Group enriched Group enriched 5 duodenum: 12.1;small intestine: 22.0 spleen: 3.2 Cell line enhanced CACO-2: 8.8;Hep G2: 15.8;U-266/70: 5.6 +ZNF558 FLJ30932 ENSG00000167785 Zinc finger protein 558 19 8806170-8832328 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA003151 Uncertain Renal cancer:1.23e-6 (unfavourable), Urothelial cancer:9.30e-5 (favourable), Head and neck cancer:1.04e-4 (favourable) Expressed in all Mixed parathyroid gland: 19.0 Mixed +CABP2 ENSG00000167791 Calcium binding protein 2 11 67518912-67524517 Disease related genes, Predicted intracellular proteins Evidence at protein level Not detected Not detected testis: 0.1 Not detected +NDUFV1 CI-51K ENSG00000167792 NADH:ubiquinone oxidoreductase core subunit V1 11 67606852-67612535 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045211, HPA075051 Approved Supported Mitochondria
Cytosol Renal cancer:7.49e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 222.1 Expressed in all +CDK2AP2 DOC-1R, p14 ENSG00000167797 Cyclin dependent kinase 2 associated protein 2 11 67506497-67508649 Predicted intracellular proteins Evidence at protein level HPA047599 Uncertain Approved Nucleoplasm Renal cancer:5.20e-4 (unfavourable), Endometrial cancer:8.80e-4 (favourable) Expressed in all Expressed in all epididymis: 50.5 Expressed in all +NUDT8 FLJ41567 ENSG00000167799 Nudix hydrolase 8 11 67627938-67629930 Predicted intracellular proteins Evidence at protein level HPA041252, HPA041466 Enhanced Approved Nucleoli
Cytosol Renal cancer:3.70e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 20.8 Cell line enhanced RPMI-8226: 155.8 +TBX10 TBX13, TBX7 ENSG00000167800 T-box 10 11 67631303-67639560 Predicted secreted proteins, Transcription factors Evidence at protein level HPA047881 Uncertain Group enriched Group enriched 27 colon: 8.8;duodenum: 5.8;rectum: 8.6;small intestine: 10.6 appendix: 0.3 Cell line enhanced NTERA-2: 5.3;RPMI-8226: 2.5;SK-BR-3: 9.3;U-2 OS: 2.7 +PRDX2 MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA ENSG00000167815 Peroxiredoxin 2 19 12796820-12801859 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008713 Approved Renal cancer:5.66e-11 (favourable) Expressed in all Expressed in all adrenal gland: 468.9 Mixed +OR8J3 ENSG00000167822 Olfactory receptor family 8 subfamily J member 3 11 56136771-56137718 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR5I1 HSOlf1, OLF1 ENSG00000167825 Olfactory receptor family 5 subfamily I member 1 11 55935456-55936400 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF232 ZSCAN11 ENSG00000167840 Zinc finger protein 232 17 5105541-5123116 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027309, HPA028611 Uncertain Supported Nucleus
Vesicles
Cytosol Liver cancer:4.66e-4 (unfavourable), Pancreatic cancer:6.55e-4 (favourable) Expressed in all Mixed ovary: 4.3 Mixed +MIS12 hMIS12, KNTC2AP, MGC2488, MTW1 ENSG00000167842 MIS12, kinetochore complex component 17 5486285-5490814 Predicted intracellular proteins Evidence at protein level HPA044482 Approved Pancreatic cancer:8.00e-4 (favourable) Expressed in all Expressed in all epididymis: 38.6 Expressed in all +CD300C CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR ENSG00000167850 CD300c molecule 17 74541108-74546143 CD markers, Predicted membrane proteins Evidence at transcript level HPA014523 Approved Testis cancer:8.53e-5 (unfavourable) Mixed Tissue enhanced lung: 12.4 appendix: 9.5 Cell line enhanced HEL: 6.4;HMC-1: 29.3;U-937: 12.8 +CD300A CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60 ENSG00000167851 CD300a molecule 17 74466416-74484796 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011645 Approved Renal cancer:1.91e-5 (unfavourable) Expressed in all Tissue enhanced spleen: 85.8 appendix: 40.0 Cell line enhanced HMC-1: 88.9;NB-4: 27.4;RPMI-8226: 57.9 +TEKT1 ENSG00000167858 Tektin 1 17 6789133-6831761 Predicted intracellular proteins Evidence at protein level HPA044444, HPA062285 Approved Endometrial cancer:6.08e-4 (favourable) Group enriched Group enriched 7 fallopian tube: 79.5;testis: 16.7 lung: 6.9 Not detected +HID1 C17orf28, DMC1, HID-1 ENSG00000167861 HID1 domain containing 17 74950743-74973166 Predicted intracellular proteins Evidence at protein level HPA023095, HPA031406 Approved Supported Golgi apparatus
Cytosol Renal cancer:3.13e-5 (favourable), Urothelial cancer:1.34e-4 (favourable) Expressed in all Expressed in all prostate: 54.2 Cell line enhanced MCF7: 89.3;SH-SY5Y: 61.4;SK-BR-3: 129.5;T-47d: 96.0 +MRPL58 DS-1, ICT1 ENSG00000167862 Mitochondrial ribosomal protein L58 17 75012670-75021261 Enzymes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003634 Approved Supported Nucleoplasm
Mitochondria Renal cancer:2.09e-4 (unfavourable) Expressed in all Expressed in all kidney: 36.1 Expressed in all +ATP5H ATP5JD, ATPQ ENSG00000167863 ATP synthase, H+ transporting, mitochondrial Fo complex subunit D 17 75038863-75046985 Predicted intracellular proteins Evidence at protein level HPA042777, HPA048459 Enhanced Supported Nucleoplasm Expressed in all Expressed in all heart muscle: 616.6 Expressed in all +TMEM88 FLJ20025, MGC71744 ENSG00000167874 Transmembrane protein 88 17 7855065-7856099 Predicted membrane proteins Evidence at protein level HPA052991 Approved Liver cancer:4.43e-6 (favourable), Colorectal cancer:1.16e-4 (unfavourable) Expressed in all Mixed placenta: 34.2 Group enriched 5 AN3-CA: 60.4;HHSteC: 35.4;HUVEC TERT2: 42.7;NTERA-2: 26.4 +EVPL EVPK ENSG00000167880 Envoplakin 17 76004502-76027452 Predicted intracellular proteins Evidence at protein level CAB002220, HPA053969 Enhanced Supported Intermediate filaments
Cytosol Mixed Group enriched 9 esophagus: 77.5;skin: 111.0 duodenum: 10.7 Cell line enhanced HaCaT: 51.8;RT4: 68.1;T-47d: 50.1 +SRP68 ENSG00000167881 Signal recognition particle 68 17 76038775-76072653 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA023303, HPA055617 Approved Enhanced Focal adhesion sites
Cytosol Liver cancer:4.28e-5 (unfavourable), Head and neck cancer:2.18e-4 (unfavourable), Thyroid cancer:2.65e-4 (favourable) Expressed in all Expressed in all thyroid gland: 71.8 Expressed in all +MGAT5B FLJ25132, GnT-IX, GnT-VB ENSG00000167889 Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 17 76868456-76950393 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011082 Approved Nucleoplasm
Cytokinetic bridge
Mitotic spindle Group enriched Tissue enriched 14 cerebral cortex: 23.1 testis: 1.6 Cell line enhanced A549: 28.7;SCLC-21H: 18.6;U-138 MG: 18.3;U-2 OS: 21.0 +TMC8 EVER2, EVIN2 ENSG00000167895 Transmembrane channel like 8 17 78130770-78142968 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA047387, HPA054429 Uncertain Uncertain Golgi apparatus Renal cancer:1.96e-7 (unfavourable), Cervical cancer:8.45e-6 (favourable), Head and neck cancer:4.19e-5 (favourable) Expressed in all Tissue enhanced lymph node: 118.8;spleen: 104.5 appendix: 72.5 Cell line enhanced HL-60: 50.1;HMC-1: 106.6;Karpas-707: 74.8;RPMI-8226: 46.3;U-266/70: 38.2;U-937: 41.2 +TK1 ENSG00000167900 Thymidine kinase 1 17 78174075-78187233 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004683 Enhanced Renal cancer:6.50e-11 (unfavourable), Lung cancer:3.03e-5 (unfavourable), Liver cancer:6.87e-4 (unfavourable) Expressed in all Mixed bone marrow: 45.7 Expressed in all +TMEM68 FLJ32370 ENSG00000167904 Transmembrane protein 68 8 55696424-55773407 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018216, HPA019173 Uncertain Approved Vesicles Expressed in all Expressed in all fallopian tube: 36.8 Expressed in all +CYP7A1 CYP7 ENSG00000167910 Cytochrome P450 family 7 subfamily A member 1 8 58490178-58500236 Enzymes, Predicted intracellular proteins Evidence at protein level Liver cancer:3.19e-4 (favourable) Tissue enriched Tissue enriched 61 liver: 26.0 duodenum: 0.4 Not detected +GSDMA FLJ39120, GSDM, GSDM1 ENSG00000167914 Gasdermin A 17 39953263-39977766 Predicted intracellular proteins, Transporters Evidence at protein level HPA023313, HPA064826 Enhanced Supported Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Tissue enhanced Tissue enriched 7 skin: 58.4 epididymis: 7.9 Cell line enhanced HBEC3-KT: 2.9;hTCEpi: 2.0;hTERT-HME1: 4.1 +KRT24 FLJ20261, MGC138169, MGC138173 ENSG00000167916 Keratin 24 17 40697991-40703750 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022978 Uncertain Approved Intermediate filaments
Cytosol Tissue enhanced Tissue enhanced epididymis: 20.3;esophagus: 28.4;tonsil: 67.0 placenta: 10.6 Cell line enriched 11 SK-BR-3: 5.3 +TMEM99 MGC21518 ENSG00000167920 Transmembrane protein 99 17 40819106-40836274 Predicted membrane proteins Evidence at transcript level Expressed in all Tissue enhanced testis: 177.0 epididymis: 53.1 Mixed +GHDC LGP1 ENSG00000167925 GH3 domain containing 17 42188799-42194532 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA031650 Uncertain Renal cancer:2.00e-6 (favourable), Glioma:5.91e-5 (unfavourable), Endometrial cancer:3.21e-4 (favourable), Ovarian cancer:5.20e-4 (unfavourable) Expressed in all Expressed in all spleen: 29.2 Mixed +FAM234A C16orf9, DKFZP761D0211, FLJ32603, ITFG3 ENSG00000167930 Family with sequence similarity 234 member A 16 234546-268971 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011651, HPA071871 Uncertain Uncertain Nucleoplasm
Mitochondria Expressed in all Expressed in all parathyroid gland: 111.8 Expressed in all +SOST DAND6, VBCH ENSG00000167941 Sclerostin 17 43753731-43758788 Disease related genes, Predicted secreted proteins Evidence at protein level CAB025660 Approved Group enriched Tissue enriched 16 kidney: 10.3 lung: 0.6 Cell line enriched 37 HaCaT: 4.6 +PRR25 gs64 ENSG00000167945 Proline rich 25 16 805443-813861 Predicted intracellular proteins No evidence HPA042974 Uncertain Not detected Not detected adipose tissue,appendix,cerebral cortex: 0.1 Not detected +ZNF598 FLJ00086 ENSG00000167962 Zinc finger protein 598 16 1997654-2009823 Predicted intracellular proteins Evidence at protein level HPA041760, HPA041896 Approved Approved Plasma membrane
Cytosol Expressed in all Mixed spleen: 11.5 Expressed in all +RAB26 ENSG00000167964 RAB26, member RAS oncogene family 16 2140803-2154165 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA075624 Uncertain Vesicles
Plasma membrane
Centrosome Cervical cancer:8.20e-5 (favourable) Mixed Tissue enhanced cerebral cortex: 21.1 liver: 11.4 Cell line enhanced A549: 18.3;HeLa: 14.7;SCLC-21H: 32.1;SK-BR-3: 18.7 +MLST8 GbetaL, GBL, Lst8, Pop3 ENSG00000167965 MTOR associated protein, LST8 homolog 16 2204248-2209416 Predicted intracellular proteins Evidence at protein level CAB019935, HPA041841 Approved Approved Nucleoplasm
Golgi apparatus
Cell Junctions Renal cancer:7.60e-4 (favourable) Expressed in all Expressed in all testis: 28.6 Expressed in all +E4F1 E4F ENSG00000167967 E4F transcription factor 1 16 2223566-2235742 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052042, HPA071325 Enhanced Nucleoplasm Head and neck cancer:1.10e-4 (favourable), Renal cancer:5.50e-4 (unfavourable), Cervical cancer:9.13e-4 (favourable) Expressed in all Expressed in all skin: 12.8 Expressed in all +DNASE1L2 DNAS1L2 ENSG00000167968 Deoxyribonuclease 1 like 2 16 2235816-2238711 Predicted secreted proteins Evidence at protein level HPA044714 Approved Mitochondria Mixed Tissue enriched 6 skin: 11.9 cerebral cortex: 1.9 Mixed +ECI1 DCI ENSG00000167969 Enoyl-CoA delta isomerase 1 16 2239395-2252300 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041746, HPA043227 Enhanced Renal cancer:8.99e-8 (favourable), Cervical cancer:3.04e-5 (favourable), Liver cancer:1.07e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 69.3 Expressed in all +CASKIN1 ANKS5A, KIAA1306 ENSG00000167971 CASK interacting protein 1 16 2177180-2196525 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055990, CAB079050 Enhanced Supported Approved Nucleus
Cytosol Mixed Tissue enriched 33 cerebral cortex: 20.3 testis: 0.6 Cell line enhanced HDLM-2: 13.8;SCLC-21H: 7.7 +ABCA3 ABC-C, ABC3, EST111653, LBM180 ENSG00000167972 ATP binding cassette subfamily A member 3 16 2275881-2340746 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA007884 Enhanced Approved Nucleoplasm
Cytosol Expressed in all Tissue enhanced lung: 135.5 cerebral cortex: 51.5 Cell line enhanced SCLC-21H: 53.9;T-47d: 71.7 +KCTD5 FLJ20040 ENSG00000167977 Potassium channel tetramerization domain containing 5 16 2682475-2709030 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all lymph node: 23.1 Expressed in all +SRRM2 Cwc21, KIAA0324, SRL300, SRm300 ENSG00000167978 Serine/arginine repetitive matrix 2 16 2752329-2772538 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041411, HPA066181 Supported Enhanced Nuclear speckles Renal cancer:4.82e-4 (unfavourable), Liver cancer:5.08e-4 (unfavourable), Head and neck cancer:6.77e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 288.8 Expressed in all +ZNF597 FLJ33071, HIT-4 ENSG00000167981 Zinc finger protein 597 16 3432422-3443542 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA001556 Approved Approved Nucleus
Nucleoli Expressed in all Mixed testis: 7.2 Mixed +NLRC3 CLR16.2, FLJ00348, NOD3 ENSG00000167984 NLR family CARD domain containing 3 16 3539033-3577400 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048062 Supported Microtubule organizing center
Cytosol Mixed Tissue enhanced lymph node: 15.7 spleen: 11.1 Cell line enhanced HEL: 7.8;HL-60: 14.5;HMC-1: 7.7;NB-4: 12.3;U-698: 19.1;U-937: 10.6 +SDHAF2 C11orf79, FLJ20487, PGL2, SDH5 ENSG00000167985 Succinate dehydrogenase complex assembly factor 2 11 61430042-61447529 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039464, HPA039732 Supported Supported Nucleoli
Mitochondria
Cytosol Expressed in all Expressed in all fallopian tube: 35.5 Expressed in all +DDB1 ENSG00000167986 Damage specific DNA binding protein 1 11 61299451-61342596 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032821, HPA045174, HPA068456 Approved Enhanced Nucleoplasm Renal cancer:1.51e-8 (favourable), Colorectal cancer:7.09e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 490.0 Expressed in all +VPS37C FLJ20847 ENSG00000167987 VPS37C, ESCRT-I subunit 11 61130256-61161617 Predicted intracellular proteins Evidence at protein level HPA043348 Approved Approved Nucleus
Vesicles Renal cancer:2.37e-7 (favourable), Liver cancer:5.85e-5 (unfavourable) Expressed in all Expressed in all skin: 25.2 Expressed in all +VWCE FLJ32009, URG11, VWC1 ENSG00000167992 Von Willebrand factor C and EGF domains 11 61258286-61295424 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040401, HPA043921 Uncertain Supported Nucleus
Vesicles
Cytosol Group enriched Tissue enhanced fallopian tube: 5.1;ovary: 5.8 liver: 3.7 Cell line enhanced Hep G2: 14.6;HSkMC: 8.6;REH: 11.0 +RAB3IL1 GRAB ENSG00000167994 RAB3A interacting protein like 1 11 61897301-61920269 Predicted intracellular proteins Evidence at protein level HPA039723 Uncertain Approved Cytosol Liver cancer:1.61e-7 (unfavourable), Renal cancer:1.49e-4 (unfavourable), Thyroid cancer:3.30e-4 (unfavourable), Colorectal cancer:6.08e-4 (unfavourable) Expressed in all Mixed testis: 48.7 Cell line enhanced K-562: 39.5;U-2197: 52.9 +BEST1 BEST, BMD, RP50, VMD2 ENSG00000167995 Bestrophin 1 11 61949821-61965515 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA057464 Supported Group enriched Mixed cerebral cortex: 17.0 Cell line enhanced SK-MEL-30: 40.9;U-266/70: 10.4 +FTH1 FHC, FTH, FTHL6, PIG15, PLIF ENSG00000167996 Ferritin heavy chain 1 11 61959718-61967660 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008623 Approved Approved Microtubules Renal cancer:5.20e-5 (unfavourable), Head and neck cancer:7.56e-5 (unfavourable), Liver cancer:6.18e-4 (unfavourable) Expressed in all Expressed in all appendix: 4962.3 Expressed in all +BSCL2 GNG3LG, SPG17 ENSG00000168000 BSCL2, seipin lipid droplet biogenesis associated 11 62690275-62709845 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042394 Approved Renal cancer:7.55e-5 (favourable) Expressed in all Expressed in all testis: 250.5 Expressed in all +POLR2G hRPB19, hsRPB7, RPB7 ENSG00000168002 RNA polymerase II subunit G 11 62761544-62766710 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA053000 Approved Supported Nucleoplasm Liver cancer:6.02e-5 (unfavourable), Renal cancer:1.11e-4 (unfavourable), Endometrial cancer:8.23e-4 (favourable) Expressed in all Expressed in all epididymis: 100.0 Expressed in all +SLC3A2 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE ENSG00000168003 Solute carrier family 3 member 2 11 62856102-62888875 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB010455, HPA017980 Enhanced Supported Nucleus
Plasma membrane
Cytosol Urothelial cancer:1.48e-4 (unfavourable), Liver cancer:8.17e-4 (unfavourable), Renal cancer:8.22e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 431.9 Expressed in all +HRASLS5 HRLP5 ENSG00000168004 HRAS like suppressor family member 5 11 63461404-63491194 Predicted intracellular proteins Evidence at protein level Glioma:9.80e-5 (unfavourable) Mixed Tissue enriched 5 testis: 96.2 adipose tissue: 17.8 Group enriched 6 HAP1: 11.7;NB-4: 2.4 +C11orf84 ENSG00000168005 Chromosome 11 open reading frame 84 11 63813388-63827718 Predicted intracellular proteins Evidence at protein level HPA040128, HPA050313 Uncertain Approved Nuclear speckles Liver cancer:1.53e-5 (unfavourable), Renal cancer:5.42e-5 (unfavourable) Expressed in all Expressed in all testis: 42.6 Expressed in all +ATG16L2 ATG16B, FLJ00012, WDR80 ENSG00000168010 Autophagy related 16 like 2 11 72814308-72843674 Predicted intracellular proteins Evidence at protein level HPA045444, HPA050312 Approved Enhanced Nucleoplasm Renal cancer:3.39e-4 (unfavourable), Pancreatic cancer:7.06e-4 (favourable) Expressed in all Expressed in all spleen: 99.0 Expressed in all +C2CD3 DKFZP586P0123 ENSG00000168014 C2 calcium dependent domain containing 3 11 74012714-74171210 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038552, HPA038553, HPA040433 Approved Approved Nucleus
Microtubule organizing center Expressed in all Mixed testis: 30.0 Expressed in all +TRANK1 KIAA0342, LBA1 ENSG00000168016 Tetratricopeptide repeat and ankyrin repeat containing 1 3 36826820-36945057 Predicted intracellular proteins Evidence at protein level HPA035508 Approved Approved Nucleoplasm Renal cancer:2.52e-5 (unfavourable) Expressed in all Mixed endometrium: 39.1 Cell line enhanced Daudi: 68.8;HMC-1: 33.4 +TTC21A IFT139A, STI2 ENSG00000168026 Tetratricopeptide repeat domain 21A 3 39107704-39138903 Predicted intracellular proteins Evidence at protein level HPA035510, HPA035511 Enhanced Supported Nucleoplasm Endometrial cancer:1.79e-4 (favourable) Mixed Tissue enriched 25 testis: 39.4 fallopian tube: 1.5 Not detected +RPSA 37LRP, LAMR1, LRP, p40, SA ENSG00000168028 Ribosomal protein SA 3 39406689-39412542 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level CAB009561 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all ovary: 2084.6 Expressed in all +ENTPD3 CD39L3, HB6, NTPDase-3 ENSG00000168032 Ectonucleoside triphosphate diphosphohydrolase 3 3 40387156-40428619 Enzymes, Predicted membrane proteins Evidence at protein level HPA071802 Approved Cytosol Mixed Tissue enhanced cervix, uterine: 33.6 urinary bladder: 14.7 Cell line enhanced HBEC3-KT: 9.3;hTCEpi: 6.3;RT4: 15.1 +CTNNB1 armadillo, beta-catenin, CTNNB ENSG00000168036 Catenin beta 1 3 41194837-41260096 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000108, CAB001950, HPA029159, HPA029160 Enhanced Enhanced Plasma membrane Colorectal cancer:7.54e-4 (favourable) Expressed in all Expressed in all placenta: 285.6 Expressed in all +ULK4 FAM7C1, FLJ20574, REC01035 ENSG00000168038 Unc-51 like kinase 4 3 41246599-41962430 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017930 Uncertain Approved Nucleoplasm
Mitochondria
Cytosol Mixed Tissue enhanced testis: 38.1 parathyroid gland: 14.4 Mixed +FADD GIG3, MORT1 ENSG00000168040 Fas associated via death domain 11 70203163-70207390 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001464, CAB010209 Supported Supported Nucleoplasm
Cytosol Lung cancer:2.21e-5 (unfavourable), Head and neck cancer:8.22e-5 (unfavourable), Thyroid cancer:3.45e-4 (favourable), Cervical cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all placenta: 20.3 Expressed in all +LTBP3 LTBP2 ENSG00000168056 Latent transforming growth factor beta binding protein 3 11 65538805-65558930 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA073170 Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 104.2 Cell line enhanced U-87 MG: 154.3 +NAALADL1 ENSG00000168060 N-acetylated alpha-linked acidic dipeptidase like 1 11 65044818-65058549 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047123 Enhanced Uncertain Cytosol Expressed in all Tissue enriched 5 small intestine: 104.2 duodenum: 20.1 Cell line enhanced fHDF/TERT166: 6.0;HHSteC: 17.2;HSkMC: 9.8;SCLC-21H: 12.7 +SAC3D1 HSU79266, SHD1 ENSG00000168061 SAC3 domain containing 1 11 65040901-65044828 Predicted intracellular proteins Evidence at protein level HPA042677 Uncertain Approved Cytosol Liver cancer:9.67e-6 (unfavourable), Renal cancer:5.66e-5 (unfavourable) Expressed in all Tissue enhanced testis: 11.6 cerebral cortex: 2.9 Mixed +BATF2 MGC20410 ENSG00000168062 Basic leucine zipper ATF-like transcription factor 2 11 64987943-64997045 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062496 Approved Approved Nucleoli Ovarian cancer:9.39e-5 (favourable), Pancreatic cancer:2.12e-4 (unfavourable) Expressed in all Mixed spleen: 17.5 Cell line enhanced BJ hTERT+ SV40 Large T+: 12.0;BJ hTERT+ SV40 Large T+ RasG12V: 19.1 +SLC22A11 OAT4 ENSG00000168065 Solute carrier family 22 member 11 11 64555626-64572875 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA026076 Approved Renal cancer:3.68e-5 (favourable) Group enriched Group enriched 114 epididymis: 10.0;kidney: 26.0;placenta: 44.8 seminal vesicle: 0.2 Cell line enhanced BEWO: 1.2 +SF1 ZCCHC25, ZFM1, ZNF162 ENSG00000168066 Splicing factor 1 11 64764606-64778786 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018883 Supported Enhanced Nucleoplasm Liver cancer:4.85e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 145.9 Expressed in all +MAP4K2 BL44, GCK, RAB8IP ENSG00000168067 Mitogen-activated protein kinase kinase kinase kinase 2 11 64784914-64803241 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007330 Enhanced Approved Vesicles Liver cancer:3.10e-5 (unfavourable) Expressed in all Mixed spleen: 22.9 Mixed +MAJIN C11orf85 ENSG00000168070 Membrane anchored junction protein 11 64937517-64972085 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 9 testis: 41.6 gallbladder: 4.5 Group enriched 9 CAPAN-2: 6.4;SiHa: 3.3 +CCDC88B BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3 ENSG00000168071 Coiled-coil domain containing 88B 11 64340223-64357534 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026652 Approved Approved Nucleoplasm
Centrosome
Cytosol Renal cancer:7.65e-5 (unfavourable), Head and neck cancer:1.48e-4 (favourable) Expressed in all Tissue enhanced spleen: 36.2 bone marrow: 31.3 Cell line enhanced HMC-1: 73.4;THP-1: 23.2 +SCARA3 APC7, CSR, CSR1, MSLR1, MSRL1 ENSG00000168077 Scavenger receptor class A member 3 8 27633868-27676776 Predicted membrane proteins Evidence at protein level HPA029861, HPA047386 Uncertain Supported Endoplasmic reticulum Expressed in all Tissue enhanced fallopian tube: 151.9 smooth muscle: 108.4 Cell line enhanced ASC TERT1: 137.0;HeLa: 151.4;HUVEC TERT2: 130.0;U-2 OS: 147.0 +PBK CT84, FLJ14385, Nori-3, SPK, TOPK ENSG00000168078 PDZ binding kinase 8 27809620-27838095 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005753, HPA050656 Enhanced Supported Approved Cytosol Renal cancer:1.18e-12 (unfavourable), Liver cancer:8.29e-5 (unfavourable), Pancreatic cancer:6.56e-4 (unfavourable) Expressed in all Tissue enriched 8 testis: 108.8 lymph node: 13.3 Mixed +SCARA5 FLJ23907, MGC45780, NET33 ENSG00000168079 Scavenger receptor class A member 5 8 27869882-27992727 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024661 Approved Mixed Mixed adipose tissue: 66.0 Cell line enriched 19 ASC diff: 157.1 +PNOC N/OFQ, NOP, PPNOC ENSG00000168081 Prepronociceptin 8 28316986-28343355 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044507, HPA056724 Enhanced Endometrial cancer:2.94e-6 (unfavourable) Tissue enriched Tissue enhanced cerebral cortex: 44.2;fallopian tube: 26.3;lymph node: 28.9 tonsil: 21.4 Group enriched 6 Daudi: 27.2;Karpas-707: 20.9;RPMI-8226: 7.7;U-698: 15.7 +COPS6 CSN6, MOV34-34KD ENSG00000168090 COP9 signalosome subunit 6 7 100088954-100092200 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044315 Approved Supported Nucleoplasm Renal cancer:6.72e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 129.6 Expressed in all +PAFAH1B2 ENSG00000168092 Platelet activating factor acetylhydrolase 1b catalytic subunit 2 11 117144267-117176894 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA051836 Approved Supported Nucleoli
Plasma membrane
Cytosol Pancreatic cancer:7.79e-5 (unfavourable), Lung cancer:3.07e-4 (unfavourable), Ovarian cancer:4.25e-4 (favourable), Liver cancer:9.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 68.2 Expressed in all +ANKS3 FLJ32345, FLJ32767, KIAA1977 ENSG00000168096 Ankyrin repeat and sterile alpha motif domain containing 3 16 4696510-4734378 Predicted intracellular proteins Evidence at protein level HPA041409, HPA041482 Uncertain Supported Nucleoplasm
Cytosol Expressed in all Mixed ovary: 8.1 Expressed in all +NUDT16L1 SDOS ENSG00000168101 Nudix hydrolase 16 like 1 16 4693694-4695859 Predicted intracellular proteins Evidence at protein level HPA044186, HPA063605 Approved Approved Plasma membrane
Cytosol Renal cancer:1.02e-6 (favourable), Lung cancer:2.79e-4 (favourable) Expressed in all Expressed in all prostate: 30.1 Expressed in all +KIAA1586 ENSG00000168116 KIAA1586 6 57046532-57055239 Predicted intracellular proteins Evidence at protein level HPA036370 Enhanced Approved Nucleus
Nuclear membrane Expressed in all Mixed testis: 14.0 Expressed in all +RAB4A HRES-1/RAB4, RAB4 ENSG00000168118 RAB4A, member RAS oncogene family 1 229271062-229305894 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all prostate: 56.2 Mixed +OR1F1 Olfmf, OR16-36, OR16-37, OR16-88, OR16-89, OR16-90, OR1F10, OR1F13P, OR1F4, OR1F5, OR1F6, OR1F7, OR1F8, OR1F9, OR3-145 ENSG00000168124 Olfactory receptor family 1 subfamily F member 1 16 3204247-3205188 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.7 Not detected +OR2B2 hs6M1-10, OR2B2Q, OR2B9, OR6-1 ENSG00000168131 Olfactory receptor family 2 subfamily B member 2 6 27911185-27912396 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +KCNJ4 HIR, hIRK2, HRK1, IRK3, Kir2.3 ENSG00000168135 Potassium voltage-gated channel subfamily J member 4 22 38426327-38455199 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Tissue enhanced Group enriched 25 cerebral cortex: 40.9;heart muscle: 11.4 gallbladder: 1.0 Cell line enriched 8 SCLC-21H: 13.4 +SETD5 FLJ10707 ENSG00000168137 SET domain containing 5 3 9397615-9479240 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB017093, HPA035574 Approved Enhanced Nucleus
Cytosol Renal cancer:4.27e-4 (unfavourable), Liver cancer:6.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.7 Expressed in all +VASN SLITL2 ENSG00000168140 Vasorin 16 4371848-4383528 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA011246, HPA016992 Uncertain Approved Nucleus
Nucleoli
Mitochondria Endometrial cancer:6.24e-5 (unfavourable) Expressed in all Mixed placenta: 16.1 Cell line enriched 14 U-2197: 640.8 +FAM83B C6orf143, FLJ30642 ENSG00000168143 Family with sequence similarity 83 member B 6 54846771-54942022 Predicted intracellular proteins Evidence at protein level HPA031464, HPA031465 Enhanced Urothelial cancer:1.86e-5 (unfavourable), Lung cancer:1.48e-4 (unfavourable), Pancreatic cancer:7.60e-4 (unfavourable) Tissue enhanced Tissue enhanced skin: 27.3 esophagus: 17.7 Cell line enhanced A-431: 17.1;HaCaT: 18.9;hTCEpi: 15.2;hTERT-HME1: 21.2;RT4: 19.6 +HIST3H3 H3.4, H3/g, H3FT, H3t ENSG00000168148 Histone cluster 3 H3 1 228424845-228425325 Predicted intracellular proteins Evidence at protein level CAB001386, CAB003812, HPA042570 Supported Supported Nucleoplasm Not detected Tissue enriched 11 testis: 2.1 adrenal gland,fallopian tube,gallbladder,skin: 0.1 Not detected +THAP9 FLJ34093 ENSG00000168152 THAP domain containing 9 4 82900684-82919969 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA037420, HPA037421 Uncertain Approved Mitochondria Renal cancer:3.50e-5 (favourable) Expressed in all Mixed testis: 11.4 Mixed +OR2C1 OLFmf3, OR2C2P ENSG00000168158 Olfactory receptor family 2 subfamily C member 1 16 3355889-3357294 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced fallopian tube: 1.1 parathyroid gland: 0.4 Not detected +RNF187 ENSG00000168159 Ring finger protein 187 1 228487061-228495766 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030098 Approved Supported Nucleoplasm
Cytosol Colorectal cancer:2.83e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 143.2 Expressed in all +HOOK3 HK3 ENSG00000168172 Hook microtubule tethering protein 3 8 42896932-43030539 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA024756 Approved Supported Golgi apparatus
Microtubule organizing center
Cytosol Renal cancer:1.32e-4 (unfavourable) Expressed in all Mixed thyroid gland: 36.6 Expressed in all +MAPK1IP1L C14orf32 ENSG00000168175 Mitogen-activated protein kinase 1 interacting protein 1 like 14 55051631-55070192 Predicted intracellular proteins Evidence at protein level HPA034506 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:4.82e-5 (favourable) Expressed in all Expressed in all bone marrow: 53.2 Expressed in all +DDIT4 Dig2, FLJ20500, REDD-1, REDD1, RTP801 ENSG00000168209 DNA damage inducible transcript 4 10 72273920-72276036 Predicted intracellular proteins Evidence at protein level HPA034507, HPA034508 Approved Supported Cytosol Renal cancer:2.54e-6 (unfavourable), Pancreatic cancer:2.78e-4 (unfavourable), Head and neck cancer:5.42e-4 (unfavourable) Expressed in all Expressed in all ovary: 220.9 Expressed in all +RBPJ CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH ENSG00000168214 Recombination signal binding protein for immunoglobulin kappa J region 4 26163455-26435131 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060647 Supported Nucleoplasm Endometrial cancer:2.98e-4 (favourable) Expressed in all Expressed in all placenta: 77.2 Expressed in all +LMBRD1 bA810I22.1, C6orf209, cblF, FLJ11240 ENSG00000168216 LMBR1 domain containing 1 6 69675802-69797111 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA019547 Uncertain Renal cancer:1.07e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 173.4 Expressed in all +ZCCHC4 FLJ23024, HSPC052, ZGRF4 ENSG00000168228 Zinc finger CCHC-type containing 4 4 25312785-25370383 Predicted intracellular proteins Evidence at protein level HPA035575, HPA035576 Uncertain Approved Nuclear speckles
Golgi apparatus Expressed in all Mixed testis: 8.2 Expressed in all +PTGDR DP, DP1, PTGDR1 ENSG00000168229 Prostaglandin D2 receptor 14 52267713-52276724 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced rectum: 8.6;spleen: 8.7 colon: 5.6 Not detected +TTC39C C18orf17, FLJ33761, HsT2697 ENSG00000168234 Tetratricopeptide repeat domain 39C 18 23992773-24135610 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA065705, HPA065713 Approved Approved Nucleoplasm Renal cancer:2.60e-5 (unfavourable), Breast cancer:1.48e-4 (favourable) Expressed in all Expressed in all liver: 47.8 Mixed +GLYCTK HBEBP2, HBEBP4 ENSG00000168237 Glycerate kinase 3 52287089-52293476 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006913 Approved Approved Golgi apparatus
Cytosol
Rods & Rings Head and neck cancer:1.64e-4 (favourable) Tissue enriched Tissue enhanced duodenum: 38.3;liver: 60.6 small intestine: 31.8 Expressed in all +GNG4 ENSG00000168243 G protein subunit gamma 4 1 235547687-235650754 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 25.3;ovary: 18.4;prostate: 17.5 endometrium: 8.4 Cell line enhanced NTERA-2: 75.6;SCLC-21H: 93.5;SH-SY5Y: 118.5 +UBTD2 DC-UbP, MGC30022 ENSG00000168246 Ubiquitin domain containing 2 5 172209640-172284071 Predicted intracellular proteins Evidence at protein level HPA035891, HPA035892 Uncertain Liver cancer:1.44e-5 (unfavourable), Colorectal cancer:5.92e-5 (favourable) Expressed in all Mixed testis: 53.4 Expressed in all +POLR2J3 ENSG00000168255 RNA polymerase II subunit J3 7 102537918-102572656 Predicted intracellular proteins, RNA polymerase related proteins Evidence at transcript level HPA011403, HPA042997, HPA044010, HPA046970 Approved Approved Nucleoplasm Mixed Expressed in all cerebral cortex: 56.5 Expressed in all +NKIRAS2 DKFZP434N1526, kappaB-Ras2, KBRAS2 ENSG00000168256 NFKB inhibitor interacting Ras like 2 17 42011382-42025644 Predicted intracellular proteins Evidence at protein level HPA062861 Approved Nucleus
Nucleoli Renal cancer:1.23e-4 (unfavourable), Liver cancer:5.56e-4 (unfavourable) Expressed in all Expressed in all placenta: 49.2 Expressed in all +DNAJC7 TPR2, TTC2 ENSG00000168259 DnaJ heat shock protein family (Hsp40) member C7 17 41976433-42021376 Predicted intracellular proteins Evidence at protein level HPA023015, HPA052395 Approved Supported Nucleoplasm
Cytosol Liver cancer:3.35e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 74.9 Expressed in all +KCNV2 Kv8.2 ENSG00000168263 Potassium voltage-gated channel modifier subfamily V member 2 9 2717502-2730037 Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA031131 Supported Tissue enriched Tissue enriched 44 testis: 6.6 skin: 0.1 Not detected +IRF2BP2 IRF-2BP2 ENSG00000168264 Interferon regulatory factor 2 binding protein 2 1 234604269-234609525 Predicted intracellular proteins Evidence at protein level HPA027815, HPA062269 Approved Enhanced Nucleoplasm Renal cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 98.7 Cell line enhanced THP-1: 189.9 +PTF1A bHLHa29, PTF1-p48 ENSG00000168267 Pancreas specific transcription factor, 1a 10 23192327-23194252 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB022612 Approved Nucleoplasm Tissue enhanced Tissue enriched 6 pancreas: 18.2 testis: 3.1 Cell line enriched 10 U-2 OS: 2.6 +NT5DC2 FLJ12442 ENSG00000168268 5'-nucleotidase domain containing 2 3 52524385-52535054 Predicted intracellular proteins Evidence at protein level HPA050683 Approved Liver cancer:2.16e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 96.1 Mixed +FOXI1 FKHL10, FREAC6 ENSG00000168269 Forkhead box I1 5 170105897-170109725 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071469 Enhanced Uncertain Nucleoli
Vesicles Group enriched Tissue enhanced breast: 10.4;kidney: 20.0 salivary gland: 6.2 Cell line enhanced MCF7: 1.2 +SMIM4 C3orf78 ENSG00000168273 Small integral membrane protein 4 3 52534013-52579237 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047771 Uncertain Approved Nucleoplasm
Mitochondria Lung cancer:1.78e-5 (favourable), Renal cancer:1.63e-4 (favourable), Pancreatic cancer:5.00e-4 (favourable) Expressed in all Expressed in all adrenal gland: 102.2 Expressed in all +COA6 C1orf31 ENSG00000168275 Cytochrome c oxidase assembly factor 6 1 234373456-234384049 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028588 Approved Supported Mitochondria Renal cancer:1.12e-5 (unfavourable), Urothelial cancer:7.12e-4 (favourable) Expressed in all Expressed in all duodenum: 45.4 Expressed in all +KIF5C ENSG00000168280 Kinesin family member 5C 2 148875250-149026759 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035210, HPA062272 Enhanced Approved Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 205.3 prostate: 44.3 Cell line enhanced AF22: 38.5;NTERA-2: 39.3;SCLC-21H: 236.2;SH-SY5Y: 49.2 +MGAT2 GNT-II ENSG00000168282 Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 14 49620795-49623481 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA043721, HPA056824 Approved Supported Golgi apparatus Cervical cancer:3.22e-4 (unfavourable) Expressed in all Expressed in all testis: 45.0 Expressed in all +BMI1 PCGF4, RNF51 ENSG00000168283 BMI1 proto-oncogene, polycomb ring finger 10 22321211-22331484 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB011120, HPA030471, HPA030472 Supported Approved Nucleus
Nucleoli
Nuclear bodies
Cytosol Liver cancer:2.60e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 86.3 Expressed in all +THAP11 CTG-B43a, CTG-B45d, HRIHFB2206 ENSG00000168286 THAP domain containing 11 16 67842082-67844195 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041434, HPA042189 Supported Enhanced Nucleoplasm
Cytokinetic bridge Expressed in all Expressed in all fallopian tube: 25.4 Expressed in all +MMADHC C2orf25, cblD, CL25022 ENSG00000168288 Methylmalonic aciduria and homocystinuria, cblD type 2 149569634-149587816 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037531, HPA037532 Supported Pancreatic cancer:2.73e-4 (unfavourable) Expressed in all Expressed in all testis: 123.1 Expressed in all +PDHB ENSG00000168291 Pyruvate dehydrogenase (lipoamide) beta 3 58427630-58433857 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033794, HPA036744, HPA036745 Enhanced Supported Nucleoplasm
Mitochondria Renal cancer:2.79e-8 (favourable) Expressed in all Expressed in all heart muscle: 112.0 Expressed in all +PXK FLJ20335 ENSG00000168297 PX domain containing serine/threonine kinase like 3 58332880-58426126 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024068 Supported Supported Plasma membrane
Microtubule organizing center
Cytosol Lung cancer:5.68e-4 (favourable) Expressed in all Expressed in all thyroid gland: 124.5 Expressed in all +HIST1H1E H1.4, H1e, H1F4, H1s-4 ENSG00000168298 Histone cluster 1 H1 family member e 6 26156354-26157107 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB011506, HPA055907 Supported Supported Nuclear speckles Mixed Tissue enriched 11 bone marrow: 36.2 lymph node: 3.3 Cell line enhanced U-266/84: 11.0;U-87 MG: 13.1 +PCMTD1 FLJ10883 ENSG00000168300 Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 8 51817575-51899186 Predicted intracellular proteins Evidence at protein level HPA025696, HPA061444 Approved Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all parathyroid gland: 186.8 Expressed in all +KCTD6 KCASH3, MGC27385 ENSG00000168301 Potassium channel tetramerization domain containing 6 3 58492114-58502360 Predicted intracellular proteins Evidence at protein level HPA036100, HPA036101 Uncertain Approved Nucleoli
Mitochondria Liver cancer:4.57e-4 (unfavourable), Renal cancer:8.63e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 40.2 Expressed in all +MPLKIP C7orf11, ORF20, TTDN1 ENSG00000168303 M-phase specific PLK1 interacting protein 7 40126023-40134659 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA058457, HPA065463 Uncertain Supported Nucleoplasm
Golgi apparatus
Vesicles Expressed in all Mixed liver: 4.3 Expressed in all +ACOX2 BRCACOX, BRCOX, THCCox ENSG00000168306 Acyl-CoA oxidase 2 3 58505136-58537319 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038280, HPA064845 Enhanced Supported Vesicles
Cytosol Tissue enhanced Tissue enhanced liver: 87.9 kidney: 42.5 Cell line enhanced ASC diff: 10.4;ASC TERT1: 17.4;fHDF/TERT166: 6.6;Hep G2: 7.0;HSkMC: 11.8 +FAM107A DRR1, TU3A ENSG00000168309 Family with sequence similarity 107 member A 3 58564117-58627610 Predicted intracellular proteins Evidence at protein level HPA055888 Enhanced Supported Nuclear speckles Liver cancer:3.38e-4 (favourable), Endometrial cancer:3.56e-4 (unfavourable) Tissue enriched Group enriched 5 cerebral cortex: 485.7;fallopian tube: 125.1 epididymis: 57.5 Group enriched 6 ASC diff: 12.6;HUVEC TERT2: 48.1 +IRF2 ENSG00000168310 Interferon regulatory factor 2 4 184387713-184474580 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030813, CAB032306, HPA057327 Supported Enhanced Nucleoplasm
Cytosol Breast cancer:6.95e-5 (favourable), Thyroid cancer:8.34e-5 (favourable) Expressed in all Expressed in all spleen: 74.2 Expressed in all +MOBP ENSG00000168314 Myelin-associated oligodendrocyte basic protein 3 39467198-39529479 Predicted intracellular proteins Evidence at protein level HPA035152 Supported Tissue enriched Tissue enriched 23 cerebral cortex: 175.9 parathyroid gland: 7.5 Cell line enriched 56 HAP1: 19.1 +CX3CR1 CCRL1, CMKBRL1, CMKDR1, GPR13, V28 ENSG00000168329 C-X3-C motif chemokine receptor 1 3 39263494-39281735 Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA030311, CAB032478, HPA046587, HPA077743 Approved Approved Nucleus Tissue enhanced Tissue enhanced cerebral cortex: 59.2 spleen: 16.6 Cell line enriched 18 RPMI-8226: 409.2 +C8orf22 ENSG00000168333 Chromosome 8 open reading frame 22 8 49054311-49076090 Predicted intracellular proteins Evidence at transcript level HPA060329 Uncertain Renal cancer:2.06e-10 (unfavourable) Group enriched Tissue enriched 79 skeletal muscle: 362.1 prostate: 4.5 Cell line enriched 13 HEL: 1.3 +XIRP1 CMYA1, DKFZp451D042, Xin ENSG00000168334 Xin actin binding repeat containing 1 3 39183210-39192596 Predicted intracellular proteins Evidence at protein level HPA016750, HPA018458, CAB026391 Enhanced Approved Nucleus
Actin filaments Tissue enhanced Group enriched 14 heart muscle: 113.0;skeletal muscle: 58.4 esophagus: 5.9 Cell line enhanced HSkMC: 3.2;RH-30: 2.9 +INSM2 IA-6, Mlt1 ENSG00000168348 INSM transcriptional repressor 2 14 35534042-35537054 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044885, HPA051925 Uncertain Approved Nucleoplasm Not detected Tissue enhanced cerebral cortex: 1.3 testis: 0.7 Cell line enriched 121 SH-SY5Y: 115.7 +DEGS2 C14orf66, DES2, FADS8 ENSG00000168350 Delta 4-desaturase, sphingolipid 2 14 100143957-100160163 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046644 Approved Nucleus
Nucleoli Renal cancer:7.94e-7 (favourable), Urothelial cancer:1.66e-4 (favourable) Mixed Tissue enhanced skin: 31.4;small intestine: 38.7 duodenum: 24.8 Cell line enriched 16 T-47d: 98.2 +SCN11A NaN, Nav1.9, SCN12A, SNS-2 ENSG00000168356 Sodium voltage-gated channel alpha subunit 11 3 38845769-38950561 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA036746, HPA036747 Uncertain Not detected Tissue enhanced placenta: 3.7;spleen: 5.3 testis: 2.0 Cell line enhanced HDLM-2: 1.1 +ARF4 ARF2 ENSG00000168374 ADP ribosylation factor 4 3 57571363-57598220 Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:7.29e-7 (unfavourable), Thyroid cancer:9.30e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 325.8 Expressed in all +SEPT2 DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3 ENSG00000168385 Septin 2 2 241315100-241354027 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017190, HPA018481 Supported Supported Nucleus
Actin filaments Liver cancer:3.66e-4 (unfavourable), Glioma:4.32e-4 (favourable) Expressed in all Expressed in all thyroid gland: 369.5 Expressed in all +FILIP1L DOC-1, GIP130 ENSG00000168386 Filamin A interacting protein 1 like 3 99830141-100114513 Predicted intracellular proteins Evidence at protein level HPA043133 Approved Approved Plasma membrane Renal cancer:9.40e-4 (unfavourable) Expressed in all Mixed smooth muscle: 217.1 Cell line enhanced HDLM-2: 74.0;TIME: 118.7 +MFSD2A FLJ14490, MFSD2 ENSG00000168389 Major facilitator superfamily domain containing 2A 1 39955112-39969968 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA043107 Uncertain Approved Plasma membrane
Cytosol
Cytoplasmic bodies Renal cancer:4.22e-6 (unfavourable), Urothelial cancer:2.33e-4 (favourable) Mixed Tissue enhanced epididymis: 116.7;seminal vesicle: 110.9 testis: 63.4 Cell line enhanced THP-1: 112.5 +DTYMK CDC8, TMPK, TYMK ENSG00000168393 Deoxythymidylate kinase 2 241675742-241686991 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042593, HPA042719 Approved Approved Mitochondria Liver cancer:1.73e-5 (unfavourable), Renal cancer:1.22e-4 (unfavourable) Expressed in all Expressed in all lymph node: 24.0 Expressed in all +TAP1 ABCB2, D6S114E, PSF1, RING4 ENSG00000168394 Transporter 1, ATP binding cassette subfamily B member 6 32845209-32853978 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB009516, HPA072354 Approved Supported Endoplasmic reticulum
Microtubule organizing center Renal cancer:6.58e-5 (unfavourable), Ovarian cancer:4.07e-4 (favourable), Colorectal cancer:9.01e-4 (favourable) Expressed in all Mixed appendix: 19.9 Mixed +ING5 FLJ23842, p28ING5 ENSG00000168395 Inhibitor of growth family member 5 2 241687085-241729478 Predicted intracellular proteins Evidence at protein level HPA042685 Approved Liver cancer:2.86e-5 (unfavourable), Pancreatic cancer:1.60e-4 (favourable) Expressed in all Expressed in all thyroid gland: 26.7 Expressed in all +ATG4B APG4B, AUTL1, DKFZp586D1822, KIAA0943 ENSG00000168397 Autophagy related 4B cysteine peptidase 2 241637213-241673857 Enzymes, Predicted intracellular proteins Evidence at protein level CAB037195, HPA069803 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.79e-4 (unfavourable), Colorectal cancer:6.85e-4 (unfavourable), Urothelial cancer:9.64e-4 (favourable) Expressed in all Expressed in all testis: 44.0 Expressed in all +BDKRB2 BK-2 ENSG00000168398 Bradykinin receptor B2 14 96204679-96244166 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA050841 Approved Mixed Mixed gallbladder: 32.5 Cell line enhanced ASC TERT1: 34.0;BJ hTERT+: 75.7;U-87 MG: 38.4 +MLKL FLJ34389 ENSG00000168404 Mixed lineage kinase domain like pseudokinase 16 74671855-74700960 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level Endometrial cancer:2.16e-4 (favourable) Expressed in all Mixed spleen: 28.9 Mixed +RFWD3 FLJ10520, RNF201 ENSG00000168411 Ring finger and WD repeat domain 3 16 74621394-74666881 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048258, HPA075649 Enhanced Nucleoplasm
Cytosol Expressed in all Mixed testis: 46.9 Expressed in all +MTNR1A MEL-1A-R ENSG00000168412 Melatonin receptor 1A 4 186533655-186555567 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Not detected Tissue enhanced kidney: 2.2;testis: 1.9 colon: 1.2 Not detected +KCNG4 Kv6.4 ENSG00000168418 Potassium voltage-gated channel modifier subfamily G member 4 16 84218667-84239750 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Not detected Not detected adrenal gland: 0.6 Not detected +RHOH ARHH, RhoH, TTF ENSG00000168421 Ras homolog family member H 4 40191053-40246967 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030345 Uncertain Mixed Tissue enhanced lymph node: 98.3;tonsil: 77.5 appendix: 47.7 Cell line enhanced Daudi: 89.6;HMC-1: 81.4;MOLT-4: 142.8;U-266/70: 49.6;U-698: 79.5 +KLHL30 FLJ43374 ENSG00000168427 Kelch like family member 30 2 238138722-238152947 Predicted intracellular proteins Evidence at transcript level HPA062095 Approved Microtubule organizing center Mixed Tissue enhanced skeletal muscle: 22.1 heart muscle: 5.6 Cell line enhanced BEWO: 3.1;RH-30: 4.4;THP-1: 1.5 +COG7 ENSG00000168434 Component of oligomeric golgi complex 7 16 23388493-23453180 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040758, HPA064645 Uncertain Enhanced Golgi apparatus Renal cancer:3.14e-4 (favourable), Endometrial cancer:6.95e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.8 Expressed in all +CDC40 EHB3, FLJ10564, PRP17, PRPF17 ENSG00000168438 Cell division cycle 40 6 110180141-110254275 Predicted secreted proteins Evidence at protein level HPA046620 Supported Nucleus Expressed in all Expressed in all thyroid gland: 27.1 Expressed in all +STIP1 HOP, STI1 ENSG00000168439 Stress induced phosphoprotein 1 11 64185272-64204543 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017448, HPA039291, HPA044062 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:6.18e-8 (unfavourable), Head and neck cancer:1.23e-4 (unfavourable) Expressed in all Expressed in all testis: 220.4 Expressed in all +SCNN1B ENaCbeta ENSG00000168447 Sodium channel epithelial 1 beta subunit 16 23278231-23381299 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA015612 Uncertain Renal cancer:2.09e-6 (unfavourable) Tissue enhanced Tissue enhanced cervix, uterine: 72.0 esophagus: 44.8 Cell line enhanced hTCEpi: 24.0;RT4: 14.6;U-266/70: 41.7;U-266/84: 14.3 +HR ALUNC, AU ENSG00000168453 HR, lysine demethylase and nuclear receptor corepressor 8 22114415-22133384 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA054888 Supported Nucleoplasm Mixed Tissue enhanced skin: 58.9 cerebral cortex: 11.9 Cell line enhanced HaCaT: 70.7;SiHa: 29.4;T-47d: 27.6 +TXNDC2 SPTRX1 ENSG00000168454 Thioredoxin domain containing 2 18 9885726-9889275 Predicted intracellular proteins Evidence at protein level CAB016414, HPA018817 Enhanced Enhanced Nucleus
Cytosol Not detected Tissue enriched 473 testis: 143.7 smooth muscle: 0.3 Cell line enhanced K-562: 1.3;U-2 OS: 1.2 +RAB31 Rab22B ENSG00000168461 RAB31, member RAS oncogene family 18 9708165-9862551 Predicted intracellular proteins Evidence at protein level HPA019717 Approved Expressed in all Expressed in all cerebral cortex: 169.8 Mixed +REEP4 C8orf20, FLJ22246, FLJ22277, PP432, Yip2c ENSG00000168476 Receptor accessory protein 4 8 22138020-22141951 Predicted membrane proteins Evidence at protein level HPA042683 Approved Approved Cytosol Renal cancer:2.88e-5 (unfavourable), Liver cancer:4.14e-5 (unfavourable) Expressed in all Expressed in all skin: 66.4 Expressed in all +TNXB TNXB1, TNXB2, TNXBS, XB, XBS ENSG00000168477 Tenascin XB 6 32041154-32115334 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced adrenal gland: 91.6 endometrium: 18.6 Cell line enhanced ASC diff: 8.6;ASC TERT1: 14.3;U-2197: 15.6;U-87 MG: 8.2 +LGI3 ENSG00000168481 Leucine rich repeat LGI family member 3 8 22146825-22157084 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA024826 Approved Cytosol Tissue enhanced Group enriched 7 cerebral cortex: 76.0;lung: 23.9;skin: 17.3;thyroid gland: 21.6 esophagus: 5.2 Cell line enhanced A549: 1.0;SCLC-21H: 1.9;SK-MEL-30: 1.3;WM-115: 1.0 +SFTPC BRICD6, PSP-C, SFTP2, SMDP2, SP-C ENSG00000168484 Surfactant protein C 8 22156913-22164479 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA010928 Enhanced Tissue enriched Tissue enriched 832 lung: 25269.5 adrenal gland: 30.3 Group enriched 9 BEWO: 9.2;NB-4: 8.0;SCLC-21H: 6.1;U-2197: 24.0 +BMP1 PCOLC ENSG00000168487 Bone morphogenetic protein 1 8 22164736-22212326 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA014572 Enhanced Renal cancer:3.37e-9 (unfavourable) Expressed in all Tissue enhanced placenta: 21.1 smooth muscle: 10.5 Mixed +ATXN2L A2D, A2lp ENSG00000168488 Ataxin 2 like 16 28823035-28837237 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041506, HPA043391, HPA071955 Approved Enhanced Cytosol Renal cancer:7.99e-7 (unfavourable), Liver cancer:9.85e-4 (unfavourable) Expressed in all Expressed in all testis: 187.6 Expressed in all +PHYHIP DYRK1AP3, KIAA0273, PAHX-AP ENSG00000168490 Phytanoyl-CoA 2-hydroxylase interacting protein 8 22219704-22232341 Predicted intracellular proteins Evidence at protein level HPA068030, HPA069318 Approved Enhanced Mitochondria Mixed Tissue enhanced cerebral cortex: 182.7;skin: 58.2 adrenal gland: 28.8 Cell line enhanced RPMI-8226: 6.4;SH-SY5Y: 3.6 +CCDC110 CT52, KM-HN-1, MGC33607 ENSG00000168491 Coiled-coil domain containing 110 4 185445182-185471759 Predicted intracellular proteins Evidence at protein level Renal cancer:1.08e-5 (favourable) Mixed Tissue enriched 14 testis: 188.3 thyroid gland: 13.2 Cell line enhanced SCLC-21H: 10.4;U-266/70: 5.6;U-266/84: 6.4 +POLR3D BN51T, RPC4, TSBN51 ENSG00000168495 RNA polymerase III subunit D 8 22245104-22254600 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA061331, HPA067875, HPA068461, HPA069089 Enhanced Enhanced Nucleoplasm Renal cancer:9.15e-6 (unfavourable), Liver cancer:1.21e-4 (unfavourable), Urothelial cancer:2.12e-4 (unfavourable) Expressed in all Expressed in all testis: 24.6 Expressed in all +FEN1 FEN-1, MF1, RAD2 ENSG00000168496 Flap structure-specific endonuclease 1 11 61792637-61797244 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002262, HPA006748 Enhanced Enhanced Nucleoplasm
Nucleoli Liver cancer:3.39e-6 (unfavourable), Renal cancer:5.73e-6 (unfavourable), Ovarian cancer:7.85e-4 (favourable), Stomach cancer:9.46e-4 (favourable) Expressed in all Mixed lymph node: 34.8 Expressed in all +SDPR cavin-2, CAVIN2, PS-p68, SDR ENSG00000168497 Serum deprivation response 2 191834302-191847255 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039325, HPA062122 Enhanced Supported Plasma membrane
Cytosol Renal cancer:8.45e-5 (favourable), Stomach cancer:3.69e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 165.9 Group enriched 6 fHDF/TERT166: 118.5;HEL: 101.3;HUVEC TERT2: 284.6;LHCN-M2: 440.0;TIME: 114.4 +MTCL1 CCDC165, KIAA0802, SOGA2 ENSG00000168502 Microtubule crosslinking factor 1 18 8705661-8832778 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046245 Uncertain Renal cancer:5.19e-4 (unfavourable), Cervical cancer:6.45e-4 (unfavourable) Mixed Mixed gallbladder: 12.8 Mixed +GBX2 ENSG00000168505 Gastrulation brain homeobox 2 2 236165236-236168369 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067809 Approved Nucleoplasm Group enriched Not detected cerebral cortex: 0.6 Cell line enhanced AF22: 47.4;PC-3: 13.2 +HFE2 haemojuvelin, hemojuvelin, HFE2A, HJV, JH, RGMC ENSG00000168509 Hemochromatosis type 2 (juvenile) 1 146017468-146036746 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Group enriched 15 heart muscle: 45.4;liver: 123.4;skeletal muscle: 212.6 esophagus: 8.6 Cell line enhanced HSkMC: 1.1;K-562: 1.4 +SCGB1D1 LIPA, LPHA, MGC71958 ENSG00000168515 Secretoglobin family 1D member 1 11 62190216-62193539 Predicted secreted proteins Evidence at protein level Group enriched Tissue enhanced cervix, uterine: 2.0;fallopian tube: 1.3 endometrium: 0.5 Cell line enriched 43 SCLC-21H: 7.1 +HEXIM2 FLJ32384 ENSG00000168517 Hexamethylene bisacetamide inducible 2 17 45160700-45170040 Predicted intracellular proteins Evidence at protein level HPA023323, HPA028455 Enhanced Supported Nucleoplasm
Nuclear speckles Endometrial cancer:2.53e-4 (favourable), Ovarian cancer:9.85e-4 (favourable) Expressed in all Expressed in all testis: 46.8 Expressed in all +FNTA FPTA, PGGT1A, PTAR2 ENSG00000168522 Farnesyltransferase, CAAX box, alpha 8 43034194-43085788 Enzymes, Predicted intracellular proteins Evidence at protein level CAB010149, HPA018830 Approved Approved Cytosol Renal cancer:2.94e-12 (unfavourable) Expressed in all Expressed in all placenta: 63.4 Expressed in all +SERINC2 FKSG84, PRO0899, TDE2, TDE2L ENSG00000168528 Serine incorporator 2 1 31409565-31434680 Predicted membrane proteins Evidence at protein level HPA005974 Enhanced Endometrial cancer:1.69e-7 (favourable), Liver cancer:2.11e-4 (unfavourable), Lung cancer:5.70e-4 (unfavourable) Expressed in all Mixed urinary bladder: 133.9 Cell line enhanced HaCaT: 290.8;HBEC3-KT: 373.3;RT4: 285.7 +MYL1 ENSG00000168530 Myosin light chain 1 2 210290150-210315190 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046859, HPA063034 Uncertain Head and neck cancer:6.59e-4 (unfavourable) Group enriched Tissue enriched 31 skeletal muscle: 7521.5 prostate: 242.5 Group enriched 11 HSkMC: 37.4;RH-30: 11.2 +TRAPPC11 C4orf41, FLJ12716, foigr, gry ENSG00000168538 Trafficking protein particle complex 11 4 183659267-183713594 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045427 Approved Nucleoplasm
Nuclear membrane Renal cancer:2.66e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 37.2 Expressed in all +CHRM1 ENSG00000168539 Cholinergic receptor muscarinic 1 11 62908679-62921807 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA014101, CAB022366 Enhanced Approved Nucleus
Cytosol Tissue enriched Group enriched 8 cerebral cortex: 39.9;prostate: 42.3;salivary gland: 11.0 adrenal gland: 3.8 Cell line enhanced MCF7: 2.7;SK-BR-3: 1.2;T-47d: 1.0 +COL3A1 EDS4A ENSG00000168542 Collagen type III alpha 1 chain 2 188974320-189012746 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007583, CAB016766, CAB059993 Approved Renal cancer:3.59e-10 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 3796.7;gallbladder: 3334.2;smooth muscle: 3029.8 placenta: 2768.0 Cell line enhanced AF22: 1344.2;ASC diff: 1690.4;ASC TERT1: 2979.5;fHDF/TERT166: 1406.5;HHSteC: 1419.6;HSkMC: 2318.4 +GFRA2 GDNFRB, NTNRA, RETL2, TRNR2 ENSG00000168546 GDNF family receptor alpha 2 8 21690403-21812357 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA024704, CAB032791 Uncertain Uncertain Vesicles Tissue enriched Tissue enhanced thyroid gland: 13.4 spleen: 9.5 Group enriched 12 HEL: 8.1;HMC-1: 17.5;WM-115: 3.6 +ING2 ING1L, p33ING2 ENSG00000168556 Inhibitor of growth family member 2 4 183504994-183511096 Predicted intracellular proteins Evidence at protein level HPA019486, HPA021517 Enhanced Supported Nucleoplasm
Golgi apparatus
Cytosol Breast cancer:5.43e-4 (favourable), Liver cancer:8.87e-4 (unfavourable) Expressed in all Expressed in all ovary: 63.3 Expressed in all +CDKN2AIP CARF, FLJ20036 ENSG00000168564 CDKN2A interacting protein 4 183444591-183448198 Predicted intracellular proteins Evidence at protein level HPA041397, HPA062142 Approved Enhanced Nucleoplasm Renal cancer:3.00e-5 (favourable) Expressed in all Expressed in all testis: 37.6 Expressed in all +SNRNP48 C6orf151, dJ336K20B.1, dJ512B11.2, FLJ32234 ENSG00000168566 Small nuclear ribonucleoprotein U11/U12 subunit 48 6 7590199-7611967 Predicted intracellular proteins Evidence at protein level HPA029234 Approved Supported Nucleoplasm
Cytosol Renal cancer:4.16e-4 (unfavourable), Breast cancer:8.30e-4 (unfavourable) Expressed in all Mixed endometrium: 10.7 Expressed in all +TMEM223 MGC3196 ENSG00000168569 Transmembrane protein 223 11 62771629-62792021 Predicted membrane proteins Evidence at protein level HPA014504 Approved Approved Nucleus
Nuclear membrane
Mitochondria Expressed in all Expressed in all spleen: 15.1 Expressed in all +SLC20A2 Glvr-2, GLVR2, MLVAR, PiT-2, Ram-1 ENSG00000168575 Solute carrier family 20 member 2 8 42416475-42541926 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA026540 Approved Renal cancer:1.01e-4 (favourable), Breast cancer:7.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 138.4 Expressed in all +CRYGA CRY-g-A, CRYG1, CRYG5 ENSG00000168582 Crystallin gamma A 2 208160740-208163576 Predicted intracellular proteins Evidence at protein level Not detected Not detected cerebral cortex,testis: 0.1 Not detected +DYNLRB2 DNCL2B, DNLC2B, ROBLD2 ENSG00000168589 Dynein light chain roadblock-type 2 16 80540734-80550760 Predicted intracellular proteins Evidence at protein level Endometrial cancer:3.91e-5 (favourable) Mixed Group enriched 8 fallopian tube: 134.8;testis: 325.7 epididymis: 27.5 Cell line enhanced MCF7: 4.4;RPTEC TERT1: 2.8;SCLC-21H: 2.2 +TMUB2 MGC3123 ENSG00000168591 Transmembrane and ubiquitin like domain containing 2 17 44186970-44191731 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043137 Approved Approved Vesicles
Cytosol Expressed in all Expressed in all testis: 48.4 Expressed in all +ADAM29 CT73, svph1 ENSG00000168594 ADAM metallopeptidase domain 29 4 174829668-174978180 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 145 testis: 73.3 endometrium: 0.5 Not detected +STAT3 APRF ENSG00000168610 Signal transducer and activator of transcription 3 17 42313324-42388568 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001671, CAB003859, HPA058603, CAB068241, CAB068242 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all gallbladder: 127.5 Mixed +ZSWIM1 C20orf162, dJ337O18.5 ENSG00000168612 Zinc finger SWIM-type containing 1 20 45881227-45885266 Predicted intracellular proteins Evidence at protein level HPA041147, HPA046751 Uncertain Approved Plasma membrane
Cytosol Pancreatic cancer:1.77e-4 (favourable), Liver cancer:5.47e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 9.3 Expressed in all +ADAM9 CORD9, KIAA0021, MCMP, MDC9, Mltng ENSG00000168615 ADAM metallopeptidase domain 9 8 38996869-39105144 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004000 Approved Endoplasmic reticulum
Vesicles Liver cancer:7.21e-6 (unfavourable), Pancreatic cancer:2.52e-5 (unfavourable), Breast cancer:1.14e-4 (unfavourable), Cervical cancer:2.25e-4 (unfavourable), Renal cancer:3.99e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 118.7 Expressed in all +ADAM18 ADAM27, tMDCIII ENSG00000168619 ADAM metallopeptidase domain 18 8 39584489-39730064 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 85 testis: 8.4 all non-specific tissues: 0.0 Not detected +GDNF ATF1, ATF2, HFB1-GDNF ENSG00000168621 Glial cell derived neurotrophic factor 5 37812677-37839686 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB005210, HPA070283 Supported Approved Nucleoplasm
Vesicles Mixed Mixed placenta: 7.0 Cell line enhanced hTEC/SVTERT24-B: 41.1;U-87 MG: 12.1;WM-115: 45.1 +DPCR1 bCX105N19.6, PBLT ENSG00000168631 Diffuse panbronchiolitis critical region 1 6 30934523-30954221 Predicted membrane proteins Evidence at protein level HPA014036 Enhanced Pancreatic cancer:6.58e-4 (unfavourable) Group enriched Tissue enriched 12 stomach: 191.3 gallbladder: 16.0 Not detected +WFDC13 C20orf138, dJ601O1.3, WAP13 ENSG00000168634 WAP four-disulfide core domain 13 20 45702016-45708817 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 319 epididymis: 106.6 seminal vesicle: 0.3 Not detected +AXIN2 DKFZp781B0869, MGC126582 ENSG00000168646 Axin 2 17 65528563-65561647 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB012283, CAB017783 Approved Uncertain Nucleus
Plasma membrane
Cytosol Pancreatic cancer:6.58e-4 (favourable) Expressed in all Mixed endometrium: 31.1 Cell line enhanced AF22: 26.9;CACO-2: 43.2;Hep G2: 53.5 +NDUFS5 CI-15k ENSG00000168653 NADH:ubiquinone oxidoreductase subunit S5 1 39026318-39034636 Predicted intracellular proteins Evidence at protein level HPA042582 Supported Ovarian cancer:3.54e-4 (favourable) Expressed in all Expressed in all epididymis: 642.7 Expressed in all +VWA3B DKFZp686F2227, MGC26733 ENSG00000168658 Von Willebrand factor A domain containing 3B 2 98087116-98313299 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036700, HPA036701 Approved Approved Nucleus Tissue enhanced Group enriched 9 fallopian tube: 41.2;testis: 36.2 lung: 4.3 Not detected +ZNF30 DKFZp686N19164, FLJ20562, KOX28 ENSG00000168661 Zinc finger protein 30 19 34926903-34945170 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA030400 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:1.16e-4 (favourable) Expressed in all Mixed fallopian tube: 5.0 Mixed +UGT3A2 ENSG00000168671 UDP glycosyltransferase family 3 member A2 5 36035017-36071358 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA059475 Uncertain Approved Nucleus
Cytosol Tissue enriched Tissue enhanced skin: 11.9;testis: 4.6 bone marrow: 3.2 Cell line enhanced HDLM-2: 6.3;MOLT-4: 9.8;REH: 25.8;T-47d: 6.7;THP-1: 11.2 +FAM84B BCMP101, NSE2 ENSG00000168672 Family with sequence similarity 84 member B 8 126552442-126558393 Predicted intracellular proteins Evidence at protein level HPA050782, HPA062115 Approved Approved Nucleoplasm Renal cancer:1.96e-8 (favourable), Urothelial cancer:1.75e-5 (favourable), Endometrial cancer:9.71e-4 (unfavourable) Expressed in all Mixed kidney: 29.6 Cell line enhanced A-431: 65.0;AN3-CA: 96.5;MCF7: 83.0;PC-3: 66.5 +LDLRAD4 C18orf1 ENSG00000168675 Low density lipoprotein receptor class A domain containing 4 18 13217498-13652755 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047633, HPA054556, HPA065246 Approved Supported Nucleoplasm
Vesicles Renal cancer:4.58e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 27.5 Cell line enhanced HEL: 34.2;MOLT-4: 94.8;REH: 32.0 +KCTD19 FLJ40162 ENSG00000168676 Potassium channel tetramerization domain containing 19 16 67289428-67326763 Predicted intracellular proteins Evidence at protein level HPA049310, HPA053321 Uncertain Not detected Tissue enriched 15 testis: 39.2 bone marrow: 2.6 Cell line enhanced HBF TERT88: 2.0;U-266/70: 4.4 +SLC16A4 MCT4, MCT5 ENSG00000168679 Solute carrier family 16 member 4 1 110362848-110391082 Predicted membrane proteins Evidence at transcript level HPA046986, HPA060163 Approved Approved Microtubules
Cytokinetic bridge
Cytosol Renal cancer:1.69e-4 (favourable) Expressed in all Tissue enhanced kidney: 125.2 placenta: 39.9 Cell line enhanced BEWO: 19.0;CAPAN-2: 26.1;SK-MEL-30: 24.1 +IL7R CD127 ENSG00000168685 Interleukin 7 receptor 5 35852695-35879603 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB010215 Approved Approved Plasma membrane
Microtubule organizing center Expressed in all Tissue enhanced appendix: 182.9;lymph node: 158.5 tonsil: 112.9 Cell line enhanced fHDF/TERT166: 149.9;HBF TERT88: 165.6;REH: 372.0 +TMEM208 HSPC171 ENSG00000168701 Transmembrane protein 208 16 67227103-67229278 Predicted membrane proteins, Transporters Evidence at protein level HPA041868, HPA041949 Supported Head and neck cancer:9.63e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 89.7 Expressed in all +LRP1B LRP-DIT, LRPDIT ENSG00000168702 LDL receptor related protein 1B 2 140231423-142131701 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA069094, HPA074788 Approved Approved Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 16.4;thyroid gland: 9.6 epididymis: 2.7 Cell line enhanced ASC diff: 1.0;HEK 293: 1.5;U-138 MG: 1.8 +WFDC12 C20orf122, dJ211D12.4, WAP2 ENSG00000168703 WAP four-disulfide core domain 12 20 45123425-45124465 Predicted secreted proteins Evidence at protein level Renal cancer:5.65e-4 (unfavourable) Group enriched Tissue enriched 12 skin: 49.7 seminal vesicle: 4.3 Not detected +AHCYL1 IRBIT, PPP1R78, XPVKONA ENSG00000168710 Adenosylhomocysteinase like 1 1 109984686-110023741 Predicted intracellular proteins Evidence at protein level HPA042589 Approved Supported Cytosol Colorectal cancer:7.00e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 253.8 Expressed in all +DNAJC21 DNAJA5, GS3, JJJ1 ENSG00000168724 DnaJ heat shock protein family (Hsp40) member C21 5 34929593-34958964 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040789, HPA049208 Approved Approved Vesicles Liver cancer:2.36e-5 (unfavourable) Expressed in all Expressed in all testis: 101.6 Expressed in all +PKIG ENSG00000168734 CAMP-dependent protein kinase inhibitor gamma 20 44531785-44624247 Predicted intracellular proteins Evidence at protein level HPA042703, HPA063690 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:4.90e-5 (favourable) Expressed in all Expressed in all heart muscle: 177.2 Cell line enhanced BJ hTERT+: 425.9 +NPNT EGFL6L, POEM ENSG00000168743 Nephronectin 4 105894775-106004027 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003711, HPA050203 Supported Approved Nucleus
Cell Junctions
Cytosol Renal cancer:8.28e-8 (favourable) Expressed in all Tissue enhanced lung: 168.4;thyroid gland: 276.0 prostate: 136.5 Cell line enhanced BEWO: 27.8;HeLa: 22.2;RPTEC TERT1: 28.6;T-47d: 48.1 +CA7 ENSG00000168748 Carbonic anhydrase 7 16 66844379-66854153 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA047237 Uncertain Tissue enhanced Tissue enhanced colon: 54.6;rectum: 49.8 small intestine: 10.7 Cell line enhanced REH: 1.0;SCLC-21H: 1.0;THP-1: 1.2 +FAM178B LOC51252 ENSG00000168754 Family with sequence similarity 178 member B 2 96875882-96986592 Predicted intracellular proteins Evidence at transcript level HPA042516, HPA062110 Uncertain Uncertain Nuclear speckles
Golgi apparatus Tissue enriched Group enriched 5 bone marrow: 11.4;epididymis: 6.7;spleen: 16.7;testis: 7.4 fallopian tube: 2.0 Cell line enhanced K-562: 23.0;RPMI-8226: 19.2;WM-115: 26.6 +TSPY2 TSPYQ1 ENSG00000168757 Testis specific protein, Y-linked 2 Y 6246223-6249019 Predicted intracellular proteins Evidence at protein level HPA049384 Supported Tissue enriched Tissue enriched 132 testis: 14.1 adipose tissue: 0.1 Group enriched 484 U-266/70: 81.8;U-266/84: 82.9 +SEMA4C Semacl1, Semaf, SEMAI ENSG00000168758 Semaphorin 4C 2 96859716-96870757 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011090 Approved Renal cancer:9.50e-7 (unfavourable), Colorectal cancer:3.53e-5 (unfavourable) Expressed in all Expressed in all placenta: 62.9 Cell line enriched 6 BEWO: 298.1 +CNNM3 ACDP3 ENSG00000168763 Cyclin and CBS domain divalent metal cation transport mediator 3 2 96816245-96833911 Predicted membrane proteins, Transporters Evidence at protein level HPA016711 Supported Approved Cytosol Expressed in all Expressed in all parathyroid gland: 45.6 Expressed in all +GSTM4 ENSG00000168765 Glutathione S-transferase mu 4 1 109656081-109674836 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048652, HPA055972, HPA055973 Approved Approved Cytokinetic bridge
Cytosol Breast cancer:9.96e-5 (favourable) Expressed in all Expressed in all duodenum: 149.7 Mixed +TET2 FLJ20032, KIAA1546 ENSG00000168769 Tet methylcytosine dioxygenase 2 4 105145875-105279816 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043135 Supported Approved Nucleoplasm Mixed Mixed bone marrow: 15.7 Mixed +CXXC4 IDAX ENSG00000168772 CXXC finger protein 4 4 104468312-104494901 Predicted intracellular proteins Evidence at protein level HPA036600, HPA036925 Uncertain Uncertain Nucleus
Golgi apparatus Pancreatic cancer:2.19e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 8.9 thyroid gland: 4.1 Cell line enhanced AF22: 6.9;AN3-CA: 9.0;Karpas-707: 6.4;SCLC-21H: 14.1;U-266/70: 7.4 +TCTN2 C12orf38, FLJ12975, JBTS24, MKS8, TECT2 ENSG00000168778 Tectonic family member 2 12 123671113-123708403 Disease related genes, Predicted membrane proteins Evidence at protein level HPA039900 Enhanced Approved Golgi apparatus
Vesicles Expressed in all Mixed fallopian tube: 46.6 Mixed +SHOX2 OG12, OG12X, SHOT ENSG00000168779 Short stature homeobox 2 3 158095954-158106503 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Tissue enhanced adipose tissue: 4.1;testis: 3.3 cervix, uterine: 2.8 Cell line enhanced SH-SY5Y: 26.1;THP-1: 28.6 +PPIP5K1 HISPPD2A, IPS1, KIAA0377, VIP1 ENSG00000168781 Diphosphoinositol pentakisphosphate kinase 1 15 43533462-43590253 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039380 Approved Supported Cytosol Renal cancer:7.14e-8 (favourable), Ovarian cancer:8.57e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 53.1 Expressed in all +TSPAN5 NET-4, TM4SF9, Tspan-5 ENSG00000168785 Tetraspanin 5 4 98470367-98658629 Predicted membrane proteins Evidence at protein level Renal cancer:7.83e-5 (unfavourable), Stomach cancer:8.56e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 75.9 ovary: 57.2 Mixed +ABHD15 ENSG00000168792 Abhydrolase domain containing 15 17 29560547-29567137 Predicted secreted proteins Evidence at protein level HPA014470 Approved Approved Nucleoplasm
Cytosol Expressed in all Mixed adipose tissue: 20.5 Mixed +ZBTB5 KIAA0354 ENSG00000168795 Zinc finger and BTB domain containing 5 9 37438114-37465399 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021521 Approved Approved Nucleoplasm
Nuclear bodies
Golgi apparatus Expressed in all Expressed in all thyroid gland: 17.6 Expressed in all +CHTF8 CTF8, DERPC, FLJ20400 ENSG00000168802 Chromosome transmission fidelity factor 8 16 69118010-69132584 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051872, HPA065522 Approved Enhanced Nucleoplasm Renal cancer:3.59e-9 (favourable) Expressed in all Expressed in all fallopian tube: 112.9 Expressed in all +ADAL ENSG00000168803 Adenosine deaminase like 15 43330674-43354555 Predicted intracellular proteins Evidence at protein level HPA046215, HPA048175 Approved Approved Microtubules Renal cancer:7.64e-9 (favourable) Expressed in all Mixed testis: 24.8 Mixed +LCMT2 KIAA0547, MGC9534, PPM2, TYW4 ENSG00000168806 Leucine carboxyl methyltransferase 2 15 43323649-43330605 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039401, HPA048176 Approved Approved Nucleoplasm
Vesicles Renal cancer:5.69e-9 (favourable) Expressed in all Mixed parathyroid gland: 13.2 Mixed +SNTB2 D16S2531E, EST25263, SNT2B2, SNT3, SNTL ENSG00000168807 Syntrophin beta 2 16 69187129-69309052 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Expressed in all Mixed parathyroid gland: 35.4 Mixed +IL12A CLMF, IL-12A, NFSK, NKSF1, p35 ENSG00000168811 Interleukin 12A 3 159988750-159996019 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA001886 Uncertain Mixed Tissue enhanced esophagus: 4.0 fallopian tube: 3.2 Cell line enhanced HDLM-2: 11.1;SK-BR-3: 12.8 +ZNF507 KIAA1084 ENSG00000168813 Zinc finger protein 507 19 32345594-32387667 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030964, HPA049728 Uncertain Supported Nucleoli
Cytosol Expressed in all Expressed in all testis: 35.0 Expressed in all +STX18 Ufe1 ENSG00000168818 Syntaxin 18 4 4415742-4542346 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003019 Approved Approved Plasma membrane Endometrial cancer:6.33e-8 (favourable), Colorectal cancer:2.84e-4 (favourable), Urothelial cancer:4.69e-4 (favourable), Renal cancer:7.03e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 180.1 Expressed in all +NSG1 ENSG00000168824 Neuron-specific protein family member 1 4 4348140-4419058 Predicted membrane proteins Evidence at protein level HPA035775 Approved Mitochondria Pancreatic cancer:9.49e-4 (favourable) Tissue enhanced Tissue enhanced skin: 143.1 cerebral cortex: 68.6 Group enriched 8 HAP1: 87.0;SCLC-21H: 199.6;SH-SY5Y: 87.5;SK-MEL-30: 63.7;TIME: 166.8;U-698: 51.3 +ZBTB49 FLJ38559, ZNF509 ENSG00000168826 Zinc finger and BTB domain containing 49 4 4290251-4321786 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024450 Approved Approved Nucleoplasm
Microtubules
Cytosol Urothelial cancer:2.88e-5 (favourable), Pancreatic cancer:1.76e-4 (favourable), Head and neck cancer:5.24e-4 (favourable) Expressed in all Mixed testis: 7.4 Expressed in all +GFM1 EFGM, EGF1, GFM ENSG00000168827 G elongation factor mitochondrial 1 3 158644278-158692575 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034764, HPA034765, HPA061405 Enhanced Approved Nucleus
Mitochondria Renal cancer:1.16e-7 (favourable), Pancreatic cancer:9.20e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 65.5 Expressed in all +OR13J1 ENSG00000168828 Olfactory receptor family 13 subfamily J member 1 9 35869263-35870601 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected cerebral cortex: 0.3 Not detected +HTR1E 5-HT1E ENSG00000168830 5-hydroxytryptamine receptor 1E 6 86937306-87016683 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA004931 Approved Not detected Tissue enhanced endometrium: 2.4;ovary: 4.9 cerebral cortex: 1.8 Group enriched 19 PC-3: 1.4;SH-SY5Y: 6.2 +FSTL5 DKFZp566D234, KIAA1263 ENSG00000168843 Follistatin like 5 4 161383897-162164035 Predicted secreted proteins Evidence at protein level Tissue enriched Group enriched 11 adrenal gland: 7.8;cerebral cortex: 16.2 testis: 1.1 Cell line enhanced HL-60: 9.8;HUVEC TERT2: 9.0;Karpas-707: 53.8;SH-SY5Y: 11.3;U-2197: 15.1 +DDX19A DDX19L, FLJ11126 ENSG00000168872 DEAD-box helicase 19A 16 70346829-70373383 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA045252, HPA066668 Approved Uncertain Nucleoplasm Liver cancer:8.05e-5 (unfavourable), Head and neck cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 51.3 Expressed in all +ATOH8 bHLHa21, FLJ14708, HATH6 ENSG00000168874 Atonal bHLH transcription factor 8 2 85751344-85788066 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028406 Supported Nucleoplasm Pancreatic cancer:8.98e-6 (favourable), Renal cancer:3.80e-5 (favourable) Tissue enhanced Tissue enhanced adipose tissue: 31.6 lung: 17.0 Cell line enhanced RH-30: 29.0;TIME: 23.5 +SOX14 SOX28 ENSG00000168875 SRY-box 14 3 137764284-137766338 Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enhanced Group enriched 19 placenta: 2.4;prostate: 1.2 all non-specific tissues: 0.0 Not detected +ANKRD49 FGIF, FLJ20189, GBIF ENSG00000168876 Ankyrin repeat domain 49 11 94493629-94499583 Predicted intracellular proteins Evidence at protein level HPA040273, HPA048137 Approved Approved Nucleus
Nucleoli
Golgi apparatus Urothelial cancer:6.16e-4 (favourable), Renal cancer:9.96e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.4 Expressed in all +SFTPB SFTP3, SP-B ENSG00000168878 Surfactant protein B 2 85657314-85668741 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002440, HPA034820, HPA062148 Enhanced Endometrial cancer:1.71e-6 (unfavourable), Renal cancer:2.99e-6 (unfavourable) Group enriched Tissue enriched 912 lung: 5318.7 adrenal gland: 5.8 Cell line enhanced BEWO: 2.8;U-2197: 6.3 +USP39 CGI-21, SAD1, SNRNP65 ENSG00000168883 Ubiquitin specific peptidase 39 2 85602856-85649282 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034823 Approved Supported Nucleoplasm Renal cancer:4.05e-7 (unfavourable), Liver cancer:2.84e-6 (unfavourable), Endometrial cancer:5.52e-4 (unfavourable) Expressed in all Expressed in all placenta: 38.4 Expressed in all +TNIP2 ABIN-2, FLIP1, KLIP, MGC4289 ENSG00000168884 TNFAIP3 interacting protein 2 4 2741648-2756376 Predicted intracellular proteins Evidence at protein level CAB020818, HPA049886, HPA063197 Supported Enhanced Nucleoplasm
Cytosol Renal cancer:2.94e-5 (unfavourable), Endometrial cancer:1.13e-4 (favourable), Lung cancer:5.73e-4 (unfavourable) Expressed in all Expressed in all placenta: 22.1 Expressed in all +C2orf68 ENSG00000168887 Chromosome 2 open reading frame 68 2 85606654-85612066 Predicted intracellular proteins Evidence at protein level HPA051143 Uncertain Approved Nucleus
Nuclear membrane
Nucleoli
Mitochondria Renal cancer:1.11e-6 (unfavourable), Endometrial cancer:1.12e-6 (unfavourable), Liver cancer:6.76e-6 (unfavourable) Expressed in all Expressed in all endometrium: 26.2 Expressed in all +TMEM150A FLJ90024, TM6P1, TMEM150, TTN1 ENSG00000168890 Transmembrane protein 150A 2 85598548-85603196 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019015 Uncertain Approved Nucleoplasm
Vesicles Expressed in all Mixed placenta: 33.4 Mixed +RNF181 HSPC238 ENSG00000168894 Ring finger protein 181 2 85595725-85597613 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046112, HPA062121 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.06e-6 (unfavourable), Thyroid cancer:4.59e-5 (favourable) Expressed in all Expressed in all thyroid gland: 171.6 Expressed in all +VAMP5 ENSG00000168899 Vesicle associated membrane protein 5 2 85584408-85593412 Predicted membrane proteins Evidence at protein level HPA035082 Supported Renal cancer:1.28e-5 (unfavourable) Expressed in all Expressed in all lung: 119.8 Cell line enhanced HUVEC TERT2: 284.0;LHCN-M2: 332.6;TIME: 191.2 +BTNL3 BTN9.1, BTNLR ENSG00000168903 Butyrophilin like 3 5 180988845-181006727 Predicted membrane proteins Evidence at transcript level Group enriched Group enriched 25 colon: 24.5;duodenum: 115.1;rectum: 26.3;small intestine: 89.1 gallbladder: 2.5 Not detected +LRRC28 FLJ34269, FLJ45242, MGC24976 ENSG00000168904 Leucine rich repeat containing 28 15 99251362-99390729 Predicted intracellular proteins Evidence at transcript level HPA039378, HPA040784, HPA066130 Approved Approved Nucleus
Golgi apparatus
Mitochondria Ovarian cancer:9.97e-5 (favourable), Cervical cancer:1.41e-4 (favourable) Expressed in all Expressed in all testis: 50.3 Expressed in all +MAT2A MATA2, MATII, SAMS2 ENSG00000168906 Methionine adenosyltransferase 2A 2 85539165-85545280 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009968, HPA043028 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:5.29e-5 (unfavourable), Melanoma:5.94e-5 (unfavourable), Liver cancer:4.87e-4 (unfavourable), Lung cancer:8.94e-4 (favourable) Expressed in all Expressed in all thyroid gland: 644.9 Expressed in all +PLA2G4F PLA2G4F/Z ENSG00000168907 Phospholipase A2 group IVF 15 42139034-42156636 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA042713, HPA056752 Enhanced Approved Nucleus
Vesicles Endometrial cancer:2.00e-4 (unfavourable) Mixed Tissue enriched 5 skin: 92.5 lung: 18.4 Cell line enhanced hTCEpi: 1.4;RT4: 6.6 +ENHO C9orf165, UNQ470 ENSG00000168913 Energy homeostasis associated 9 34521040-34523041 Predicted secreted proteins Evidence at transcript level HPA042575 Approved Endometrial cancer:3.71e-4 (unfavourable) Tissue enhanced Tissue enriched 12 cerebral cortex: 140.3 testis: 11.5 Cell line enhanced AN3-CA: 14.6;NTERA-2: 21.5;SCLC-21H: 12.8;SH-SY5Y: 10.9 +ZNF608 DKFZp434M098, KIAA1281, NY-REN-36 ENSG00000168916 Zinc finger protein 608 5 124636913-124748807 Predicted intracellular proteins Evidence at protein level HPA005545 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.28e-5 (unfavourable), Endometrial cancer:5.47e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 18.2 Cell line enhanced AF22: 60.2;REH: 100.7 +SLC35G2 DKFZp564K2464, MGC3295, TMEM22 ENSG00000168917 Solute carrier family 35 member G2 3 136818647-136855892 Predicted membrane proteins, Transporters Evidence at protein level HPA052054, HPA064728 Approved Supported Plasma membrane Renal cancer:1.16e-7 (unfavourable) Mixed Mixed testis: 21.3 Cell line enhanced BJ hTERT+: 59.1 +INPP5D hp51CN, SHIP, SHIP1 ENSG00000168918 Inositol polyphosphate-5-phosphatase D 2 233059967-233207903 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016300, HPA070455 Uncertain Approved Cytosol Head and neck cancer:2.03e-5 (favourable) Expressed in all Mixed lymph node: 39.3 Cell line enhanced HEL: 84.8;HMC-1: 83.7;hTCEpi: 63.0;NB-4: 56.4 +LETM1 ENSG00000168924 Leucine zipper and EF-hand containing transmembrane protein 1 4 1811479-1856247 Predicted membrane proteins, Transporters Evidence at protein level HPA011029, HPA011100 Enhanced Enhanced Mitochondria Prostate cancer:1.77e-4 (unfavourable), Liver cancer:1.79e-4 (unfavourable), Renal cancer:8.90e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 16.3 Expressed in all +CTRB1 CTRB ENSG00000168925 Chymotrypsinogen B1 16 75219000-75224924 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Tissue enriched Tissue enriched 376 pancreas: 48923.8 ovary: 130.0 Cell line enhanced EFO-21: 2.9;HDLM-2: 2.3;U-2 OS: 2.4;U-266/84: 1.0 +CTRB2 ENSG00000168928 Chymotrypsinogen B2 16 75204096-75207185 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 392 pancreas: 29060.0 ovary: 74.0 Cell line enhanced EFO-21: 3.0;U-2 OS: 6.8;U-251 MG: 1.5;U-266/84: 1.9 +TRIM49 RNF18, TRIM49A ENSG00000168930 Tripartite motif containing 49 11 89797655-89808575 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.3 Not detected +TMEM129 D4S2561E ENSG00000168936 Transmembrane protein 129 4 1715952-1721358 Enzymes, Predicted membrane proteins Evidence at protein level HPA060920 Approved Vesicles Renal cancer:9.64e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 36.1 Expressed in all +PPIC CYPC ENSG00000168938 Peptidylprolyl isomerase C 5 123023250-123036741 Enzymes, Predicted secreted proteins Evidence at protein level HPA039163 Approved Liver cancer:4.78e-4 (unfavourable) Expressed in all Mixed thyroid gland: 77.6 Mixed +SPRY3 HSPRY3 ENSG00000168939 Sprouty RTK signaling antagonist 3 X 155767812-155782459 Predicted membrane proteins Evidence at transcript level CAB013505 Uncertain Approved Nucleoli
Cytosol Mixed Mixed epididymis: 2.6 Cell line enhanced AN3-CA: 3.4 +CEP120 CCDC100, FLJ36090 ENSG00000168944 Centrosomal protein 120 5 123344885-123423592 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028823, HPA051556 Uncertain Approved Microtubules
Cytosol Expressed in all Expressed in all testis: 29.7 Expressed in all +STXBP6 amisyn, HSPC156 ENSG00000168952 Syntaxin binding protein 6 14 24809656-25050297 Predicted intracellular proteins Evidence at protein level HPA003552 Approved Mixed Mixed placenta: 61.2 Cell line enhanced HBF TERT88: 62.1 +TM4SF20 FLJ22800, TCCE518 ENSG00000168955 Transmembrane 4 L six family member 20 2 227362156-227381995 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA051838, HPA063184, HPA065531 Uncertain Supported Plasma membrane
Focal adhesion sites Group enriched Group enriched 35 duodenum: 277.2;small intestine: 163.8 testis: 6.3 Cell line enhanced A549: 2.5;RPMI-8226: 1.2 +MFF C2orf33, GL004 ENSG00000168958 Mitochondrial fission factor 2 227325151-227357836 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010968, HPA074625 Approved Supported Mitochondria Liver cancer:1.20e-4 (unfavourable) Expressed in all Expressed in all testis: 353.8 Expressed in all +GRM5 GPRC1E, mGlu5, MGLUR5, PPP1R86 ENSG00000168959 Glutamate metabotropic receptor 5 11 88504576-89065945 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 8 cerebral cortex: 27.2 testis: 3.2 Not detected +LGALS9 LGALS9A ENSG00000168961 Galectin 9 17 27629798-27649560 Predicted intracellular proteins Evidence at protein level HPA046876, HPA047218 Approved Approved Cytosol Renal cancer:1.52e-5 (unfavourable), Cervical cancer:2.35e-5 (favourable) Expressed in all Mixed rectum: 42.0 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 23.0;HMC-1: 54.5;MOLT-4: 26.1;THP-1: 38.7;U-937: 38.5 +JMJD7-PLA2G4B ENSG00000168970 JMJD7-PLA2G4B readthrough 15 41828095-41848155 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA005726 Uncertain Approved Cytosol Mixed Mixed lung: 1.6 Mixed +CPLX1 CPX-I ENSG00000168993 Complexin 1 4 784957-826198 Predicted intracellular proteins Evidence at protein level HPA071191 Uncertain Vesicles Cervical cancer:4.20e-4 (unfavourable), Pancreatic cancer:5.05e-4 (favourable) Expressed in all Tissue enriched 11 cerebral cortex: 60.2 adipose tissue: 5.3 Cell line enriched 7 SCLC-21H: 95.0 +PXDC1 C6orf145 ENSG00000168994 PX domain containing 1 6 3722614-3752026 Predicted intracellular proteins Evidence at protein level HPA019246 Approved Plasma membrane Endometrial cancer:1.14e-4 (unfavourable), Colorectal cancer:3.64e-4 (unfavourable) Expressed in all Mixed placenta: 82.7 Mixed +SIGLEC7 CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2 ENSG00000168995 Sialic acid binding Ig like lectin 7 19 51142299-51153526 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced spleen: 21.0 appendix: 14.4 Group enriched 10 Karpas-707: 39.7;RPMI-8226: 23.1;U-937: 27.4 +NTSR2 NTR2 ENSG00000169006 Neurotensin receptor 2 2 11658178-11670164 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 25 cerebral cortex: 25.0 ovary: 0.9 Not detected +E2F6 E2F-6 ENSG00000169016 E2F transcription factor 6 2 11444375-11466177 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA075185 Supported Nucleoplasm Liver cancer:1.20e-5 (unfavourable), Endometrial cancer:7.13e-4 (unfavourable) Expressed in all Mixed endometrium: 7.2 Expressed in all +FEM1B ENSG00000169018 Fem-1 homolog B 15 68277803-68295865 Predicted intracellular proteins Evidence at protein level HPA041920, HPA042192 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 105.4 Expressed in all +COMMD8 FLJ20502 ENSG00000169019 COMM domain containing 8 4 47450796-47463719 Predicted intracellular proteins Evidence at protein level HPA035887 Approved Supported Nucleoplasm
Cytosol Renal cancer:2.71e-5 (favourable), Liver cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all kidney: 46.4 Expressed in all +ATP5I ENSG00000169020 ATP synthase, H+ transporting, mitochondrial Fo complex subunit E 4 672436-674338 Predicted intracellular proteins Evidence at protein level HPA035010 Supported Enhanced Mitochondria Expressed in all Expressed in all skeletal muscle: 541.4 Expressed in all +UQCRFS1 RIP1, RIS1, RISP, UQCR5 ENSG00000169021 Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 19 29205321-29213541 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041863, HPA050339 Enhanced Enhanced Mitochondria Renal cancer:3.92e-9 (favourable), Colorectal cancer:3.29e-4 (favourable), Ovarian cancer:3.84e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 70.9 Expressed in all +MFSD7 FLJ22269, LP2561 ENSG00000169026 Major facilitator superfamily domain containing 7 4 681829-689441 Predicted membrane proteins Evidence at transcript level HPA043593 Uncertain Renal cancer:2.66e-5 (favourable) Expressed in all Mixed parathyroid gland: 13.0 Cell line enhanced BEWO: 7.9;T-47d: 24.0 +COL4A3 ENSG00000169031 Collagen type IV alpha 3 chain 2 227164565-227314792 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042064 Approved Approved Endoplasmic reticulum
Vesicles Renal cancer:2.51e-7 (favourable) Group enriched Tissue enhanced thyroid gland: 26.8 lung: 22.4 Cell line enhanced HeLa: 10.8;Karpas-707: 7.1;RPTEC TERT1: 8.3;U-266/70: 6.7 +MAP2K1 MAPKK1, MEK1, PRKMK1 ENSG00000169032 Mitogen-activated protein kinase kinase 1 15 66386817-66492312 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB003834, HPA026430 Approved Enhanced Plasma membrane
Cytosol Glioma:2.68e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 144.4 Expressed in all +KLK7 PRSS6, SCCE ENSG00000169035 Kallikrein related peptidase 7 19 50976482-50984099 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018994, CAB026342, HPA062126 Enhanced Supported Nuclear membrane
Plasma membrane Endometrial cancer:8.06e-5 (unfavourable), Pancreatic cancer:1.16e-4 (unfavourable) Tissue enhanced Group enriched 5 esophagus: 68.7;skin: 219.6 fallopian tube: 27.9 Group enriched 6 CAPAN-2: 7.1;HaCaT: 28.1 +HNRNPH1 hnRNPH, HNRPH1 ENSG00000169045 Heterogeneous nuclear ribonucleoprotein H1 5 179614178-179634784 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000914, HPA001359, HPA016884, CAB032820 Supported Supported Nucleoplasm
Cytosol Liver cancer:3.29e-7 (unfavourable), Renal cancer:3.46e-4 (unfavourable), Head and neck cancer:7.85e-4 (favourable) Expressed in all Expressed in all endometrium: 203.6 Expressed in all +IRS1 HIRS-1 ENSG00000169047 Insulin receptor substrate 1 2 226731317-226799759 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005261, HPA046433 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Mixed thyroid gland: 33.9 Mixed +MECP2 MRX16, MRX79, RTT ENSG00000169057 Methyl-CpG binding protein 2 X 154021573-154137103 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000593, HPA001341, CAB037264 Enhanced Supported Nucleus Renal cancer:7.32e-9 (favourable), Endometrial cancer:8.35e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.7 Expressed in all +VCX3A VCX-8r, VCX-A, VCX3 ENSG00000169059 Variable charge, X-linked 3A X 6533618-6535118 Predicted intracellular proteins Evidence at protein level HPA044996, HPA049357 Supported Mixed Tissue enriched 205 testis: 27.5 placenta: 0.1 Cell line enhanced HMC-1: 4.3;PC-3: 2.3;U-138 MG: 7.3;U-266/70: 3.5 +UPF3A HUPF3A, RENT3A, UPF3 ENSG00000169062 UPF3 regulator of nonsense transcripts homolog A (yeast) 13 114281584-114305817 Predicted intracellular proteins Evidence at protein level HPA018325, HPA061316 Approved Approved Nucleus
Vesicles
Cytosol Pancreatic cancer:7.09e-5 (favourable), Urothelial cancer:3.71e-4 (favourable) Expressed in all Expressed in all testis: 84.4 Expressed in all +ZBBX FLJ23049 ENSG00000169064 Zinc finger B-box domain containing 3 167240287-167381346 Predicted intracellular proteins Evidence at protein level HPA036327, HPA036328 Enhanced Tissue enhanced Group enriched 10 fallopian tube: 38.1;testis: 67.6 lung: 5.5 Not detected +ACTBL2 DKFZp686D0972 ENSG00000169067 Actin, beta like 2 5 57480016-57482809 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041264, HPA041271 Uncertain Not detected Not detected cervix, uterine: 0.3 Cell line enhanced RPTEC TERT1: 1.2;SiHa: 3.0;U-2 OS: 1.8 +ROR2 BDB, BDB1, NTRKR2 ENSG00000169071 Receptor tyrosine kinase like orphan receptor 2 9 91563091-91950162 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA021868 Uncertain Thyroid cancer:4.28e-8 (unfavourable), Renal cancer:9.86e-7 (unfavourable) Mixed Tissue enhanced parathyroid gland: 35.1 endometrium: 21.4 Cell line enhanced AF22: 25.3;HHSteC: 55.3;HSkMC: 39.9;U-266/70: 29.6 +AR AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1 ENSG00000169083 Androgen receptor X 67544032-67730619 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000001, HPA065701, CAB065764 Enhanced Approved Mitochondria Renal cancer:1.03e-8 (favourable), Liver cancer:8.77e-4 (favourable) Mixed Mixed fallopian tube: 42.3 Cell line enhanced AF22: 15.6;HAP1: 21.1;LHCN-M2: 14.9;RH-30: 28.3 +DHRSX DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6 ENSG00000169084 Dehydrogenase/reductase X-linked X 2219516-2502805 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003035 Approved Approved Actin filaments
Cytosol Expressed in all Expressed in all thyroid gland: 17.1 Mixed +C8orf46 MGC33510 ENSG00000169085 Chromosome 8 open reading frame 46 8 66460003-66518524 Predicted intracellular proteins Evidence at protein level HPA075134 Approved Nuclear speckles Tissue enriched Tissue enriched 14 cerebral cortex: 65.1 seminal vesicle: 4.5 Cell line enhanced LHCN-M2: 1.8;SK-MEL-30: 1.9;T-47d: 2.8;WM-115: 2.9 +HSPBAP1 FLJ22623, PASS1 ENSG00000169087 HSPB1 associated protein 1 3 122740003-122793824 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044930 Approved Approved Mitochondria Expressed in all Mixed testis: 19.3 Expressed in all +ASMTL ENSG00000169093 Acetylserotonin O-methyltransferase-like X 1403139-1453762 Predicted intracellular proteins Evidence at protein level HPA003630, HPA021865 Enhanced Enhanced Cytosol Expressed in all Expressed in all thyroid gland: 34.4 Expressed in all +SLC25A6 ANT3, ANT3Y, MGC17525 ENSG00000169100 Solute carrier family 25 member 6 X 1386152-1392724 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA046835, HPA071684 Approved Supported Mitochondria Expressed in all Expressed in all ovary: 291.7 Expressed in all +CHST14 D4ST-1, D4ST1, HD4ST ENSG00000169105 Carbohydrate sulfotransferase 14 15 40470998-40474571 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA057697, HPA071601 Approved Approved Vesicles Expressed in all Expressed in all placenta: 38.8 Expressed in all +PARM1 Cipar1, DKFZP564O0823, WSC4 ENSG00000169116 Prostate androgen-regulated mucin-like protein 1 4 74933095-75050115 Predicted membrane proteins Evidence at protein level HPA038236 Approved Approved Nucleus
Vesicles
Cytosol Thyroid cancer:1.78e-4 (unfavourable) Expressed in all Mixed thyroid gland: 206.6 Cell line enhanced ASC diff: 30.6;Karpas-707: 32.2;U-266/70: 37.9 +CSNK1G1 CK1gamma1 ENSG00000169118 Casein kinase 1 gamma 1 15 64165517-64356259 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018209 Supported Cytosol Expressed in all Tissue enhanced testis: 59.9 thyroid gland: 13.9 Expressed in all +FAM110B C8orf72, MGC39325 ENSG00000169122 Family with sequence similarity 110 member B 8 57994509-58204279 Predicted intracellular proteins Evidence at protein level HPA008318, HPA011781 Uncertain Supported Mitochondria
Cytosol Endometrial cancer:3.88e-8 (unfavourable), Renal cancer:4.31e-8 (favourable), Pancreatic cancer:1.44e-4 (favourable) Mixed Tissue enhanced spleen: 28.2 cerebral cortex: 17.7 Cell line enhanced RPTEC TERT1: 9.6 +ARMC4 CILD23, DKFZP434P1735, FLJ10376, FLJ10817 ENSG00000169126 Armadillo repeat containing 4 10 27812164-27999048 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037829 Enhanced Mixed Group enriched 11 fallopian tube: 28.9;testis: 40.2 prostate: 3.2 Cell line enhanced AF22: 6.0;RH-30: 14.9 +AFAP1L2 Em:AC005383.4, FLJ14564, KIAA1914, XB130 ENSG00000169129 Actin filament associated protein 1 like 2 10 114294824-114404756 Predicted intracellular proteins Evidence at protein level HPA037843 Approved Supported Plasma membrane
Cytosol Renal cancer:1.55e-5 (unfavourable), Pancreatic cancer:3.76e-4 (unfavourable) Expressed in all Tissue enhanced thyroid gland: 138.0 parathyroid gland: 94.7 Cell line enhanced A-431: 64.5;CAPAN-2: 68.1;EFO-21: 53.1;HaCaT: 87.3;RPMI-8226: 36.0;RPTEC TERT1: 45.2 +ZNF354A EZNF, HKL1, KID-1, KID1, TCF17 ENSG00000169131 Zinc finger protein 354A 5 178694605-178730702 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052043 Approved Supported Nucleus
Nucleoli
Cytosol Renal cancer:3.45e-6 (unfavourable), Ovarian cancer:8.28e-4 (favourable) Expressed in all Expressed in all testis: 15.7 Mixed +ATF5 ENSG00000169136 Activating transcription factor 5 19 49928702-49933935 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030187 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:3.39e-7 (unfavourable), Cervical cancer:1.14e-4 (favourable), Endometrial cancer:1.16e-4 (unfavourable) Tissue enriched Group enriched 7 liver: 387.6;thyroid gland: 190.2 appendix: 42.4 Expressed in all +UBE2V2 DDVit-1, DDVIT1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2 ENSG00000169139 Ubiquitin conjugating enzyme E2 V2 8 48008400-48064708 Predicted intracellular proteins Evidence at protein level HPA052535, HPA053186 Supported Nucleoplasm Renal cancer:4.96e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 97.6 Expressed in all +GOT1L1 MGC33309 ENSG00000169154 Glutamic-oxaloacetic transaminase 1-like 1 8 37934281-37940129 Predicted intracellular proteins Evidence at transcript level HPA028778 Uncertain Not detected Tissue enriched 26 testis: 21.5 ovary: 0.8 Not detected +ZBTB43 FLJ22470, KIAA0414, ZBTB22B, ZNF-X, ZNF297B ENSG00000169155 Zinc finger and BTB domain containing 43 9 126805006-126838210 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016825 Approved Approved Nucleus
Nucleoli Renal cancer:8.73e-4 (favourable) Expressed in all Expressed in all bone marrow: 38.8 Expressed in all +CPT1C CPT1P, CPTIC, FLJ23809 ENSG00000169169 Carnitine palmitoyltransferase 1C 19 49690898-49713731 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014529, HPA063621 Approved Approved Centrosome Pancreatic cancer:1.84e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 34.2 adrenal gland: 7.0 Cell line enhanced AF22: 39.0;SH-SY5Y: 74.9 +PCSK9 FH3, HCHOLA3, NARC-1 ENSG00000169174 Proprotein convertase subtilisin/kexin type 9 1 55039548-55064852 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Urothelial cancer:2.40e-4 (unfavourable) Mixed Tissue enhanced liver: 6.1;lung: 11.1 colon: 3.4 Cell line enhanced A-431: 72.0;HaCaT: 94.8;HeLa: 62.7;RPTEC TERT1: 39.4 +XPO6 FLJ22519, KIAA0370, RANBP20 ENSG00000169180 Exportin 6 16 28097979-28211920 Predicted intracellular proteins Evidence at protein level HPA038246 Uncertain Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Liver cancer:3.68e-4 (unfavourable), Urothelial cancer:8.80e-4 (unfavourable) Expressed in all Expressed in all testis: 93.8 Expressed in all +GSG1L KTSR5831, MGC18079, PRO19651 ENSG00000169181 GSG1 like 16 27787535-28063509 Predicted membrane proteins, Transporters Evidence at protein level HPA014479 Approved Tissue enriched Tissue enhanced cerebral cortex: 11.7;heart muscle: 7.3 fallopian tube: 2.7 Group enriched 7 HMC-1: 7.3;THP-1: 2.1 +MN1 MGCR, MGCR1, MGCR1-PEN ENSG00000169184 MN1 proto-oncogene, transcriptional regulator 22 27748277-27801498 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003072 Approved Approved Nucleoplasm Mixed Tissue enhanced skeletal muscle: 22.0 cerebral cortex: 6.4 Cell line enhanced AF22: 31.4;RH-30: 12.4;TIME: 16.8;U-2 OS: 17.9;U-2197: 17.1 +APEX2 APE2, APEXL2, XTH2, ZGRF2 ENSG00000169188 Apurinic/apyrimidinic endodeoxyribonuclease 2 X 55000357-55009057 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048577 Supported Nucleus
Nucleoli fibrillar center
Vesicles Liver cancer:6.13e-7 (unfavourable), Ovarian cancer:5.21e-4 (favourable), Cervical cancer:6.17e-4 (favourable), Urothelial cancer:6.63e-4 (favourable) Expressed in all Expressed in all skin: 14.3 Expressed in all +NSMCE1 NSE1 ENSG00000169189 NSE1 homolog, SMC5-SMC6 complex component 16 27224991-27268794 Predicted intracellular proteins Evidence at protein level HPA041567, HPA043091 Enhanced Supported Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 122.9 Expressed in all +CCDC126 FLJ23031 ENSG00000169193 Coiled-coil domain containing 126 7 23597379-23644708 Predicted intracellular proteins Evidence at protein level HPA026883 Uncertain Approved Nucleoplasm Expressed in all Expressed in all testis: 62.2 Expressed in all +IL13 ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600 ENSG00000169194 Interleukin 13 5 132656263-132661110 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA042421 Approved Plasma membrane
Cytosol Not detected Tissue enriched 10 testis: 19.9 gallbladder: 2.0 Cell line enriched 226 HDLM-2: 38.1 +NPIPB12 ENSG00000169203 Nuclear pore complex interacting protein family, member B12 16 29483642-29505999 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Not detected Expressed in all skin: 133.9 Expressed in all +OR10G3 ENSG00000169208 Olfactory receptor family 10 subfamily G member 3 14 21569803-21570744 G-protein coupled receptors, Predicted membrane proteins No evidence HPA019766 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +RAB3B ENSG00000169213 RAB3B, member RAS oncogene family 1 51907956-51990764 Predicted intracellular proteins Evidence at protein level HPA003159, CAB023293 Enhanced Approved Cell Junctions Group enriched Tissue enhanced cerebral cortex: 8.2;prostate: 17.8 adrenal gland: 4.0 Cell line enhanced BJ: 105.7;TIME: 79.3 +OR6F1 OST731 ENSG00000169214 Olfactory receptor family 6 subfamily F member 1 1 247711829-247712755 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 21 testis: 2.1 all non-specific tissues: 0.0 Not detected +CD2BP2 LIN1, PPP1R59, Snu40 ENSG00000169217 CD2 cytoplasmic tail binding protein 2 16 30350766-30355361 Predicted intracellular proteins Evidence at protein level HPA041508, HPA061309 Enhanced Enhanced Nuclear speckles
Cytosol Liver cancer:1.84e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 80.8 Expressed in all +RSPO1 FLJ40906, RSPONDIN ENSG00000169218 R-spondin 1 1 37611350-37634923 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046154 Uncertain Tissue enriched Tissue enhanced endometrium: 43.4;fallopian tube: 33.1 smooth muscle: 21.2 Cell line enhanced NTERA-2: 1.3 +RGS14 ENSG00000169220 Regulator of G-protein signaling 14 5 177357837-177372601 Predicted intracellular proteins Evidence at protein level HPA046847, HPA061819 Enhanced Enhanced Nucleoplasm
Vesicles Liver cancer:1.84e-6 (unfavourable), Glioma:9.11e-4 (unfavourable) Expressed in all Mixed spleen: 21.7 Cell line enhanced HDLM-2: 101.9;HMC-1: 82.1;RPMI-8226: 39.1 +TBC1D10B DKFZP434P1750, EPI64B, FLJ13130, Rab27A-GAPbeta ENSG00000169221 TBC1 domain family member 10B 16 30357102-30370264 Predicted intracellular proteins Evidence at protein level HPA048894 Uncertain Liver cancer:8.94e-5 (unfavourable), Colorectal cancer:1.35e-4 (unfavourable) Expressed in all Expressed in all testis: 36.1 Expressed in all +LMAN2 C5orf8, GP36B, VIP36 ENSG00000169223 Lectin, mannose binding 2 5 177331562-177351852 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003927 Approved Renal cancer:8.53e-4 (unfavourable) Expressed in all Expressed in all epididymis: 164.8 Expressed in all +GCSAML C1orf150, FLJ44728 ENSG00000169224 Germinal center associated signaling and motility like 1 247507058-247577690 Predicted intracellular proteins Evidence at protein level HPA027507, HPA027510 Uncertain Approved Cytosol Tissue enriched Tissue enhanced prostate: 9.1;testis: 7.3 lung: 3.3 Group enriched 98 HEL: 133.3;HMC-1: 495.5 +RAB24 ENSG00000169228 RAB24, member RAS oncogene family 5 177301198-177303744 Predicted intracellular proteins Evidence at protein level HPA034945 Uncertain Focal adhesion sites Renal cancer:2.54e-7 (unfavourable), Liver cancer:7.56e-5 (unfavourable), Head and neck cancer:6.22e-4 (favourable) Expressed in all Expressed in all spleen: 40.1 Expressed in all +PRELID1 CGI-106, PRELI, PX19 ENSG00000169230 PRELI domain containing 1 5 177303774-177306959 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005701 Approved Supported Nucleoplasm
Mitochondria Renal cancer:2.89e-7 (unfavourable), Liver cancer:5.46e-5 (unfavourable) Expressed in all Expressed in all small intestine: 130.3 Expressed in all +THBS3 ENSG00000169231 Thrombospondin 3 1 155195588-155209051 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006293, HPA073242 Approved Approved Vesicles Renal cancer:2.38e-12 (unfavourable), Endometrial cancer:1.44e-4 (unfavourable), Colorectal cancer:2.43e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 41.6 Cell line enhanced SCLC-21H: 49.1 +CA5B ENSG00000169239 Carbonic anhydrase 5B X 15688830-15788409 Enzymes, Predicted intracellular proteins Evidence at protein level HPA012618 Uncertain Supported Mitochondria Renal cancer:6.66e-6 (favourable) Expressed in all Mixed cervix, uterine: 34.1 Cell line enhanced hTERT-HME1: 26.3 +SLC50A1 HsSWEET1, RAG1AP1, RP11-540D14.5, RZPDo834D038D, SCP, slv, SWEET1 ENSG00000169241 Solute carrier family 50 member 1 1 155135344-155138857 Predicted membrane proteins, Transporters Evidence at protein level HPA018095 Approved Renal cancer:3.88e-7 (unfavourable) Expressed in all Expressed in all epididymis: 135.2 Expressed in all +EFNA1 ECKLG, EPLG1, LERK1, TNFAIP4 ENSG00000169242 Ephrin A1 1 155127460-155134857 Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB032498 Uncertain Expressed in all Mixed placenta: 123.9 Cell line enhanced BEWO: 211.4;SiHa: 136.8;SK-BR-3: 146.1 +CXCL10 C7, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10 ENSG00000169245 C-X-C motif chemokine ligand 10 4 76021117-76023497 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.16e-6 (unfavourable), Ovarian cancer:1.12e-5 (favourable), Pancreatic cancer:4.61e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 129.4 lymph node: 72.5 Cell line enhanced BJ hTERT+: 4.9;BJ hTERT+ SV40 Large T+: 2.0;BJ hTERT+ SV40 Large T+ RasG12V: 2.1;RPMI-8226: 2.9;THP-1: 2.0 +NPIPB3 KIAA0220, NPIPL3 ENSG00000169246 Nuclear pore complex interacting protein family member B3 16 21402237-21448567 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Mixed Expressed in all skin: 189.3 Expressed in all +SH3TC2 CMT4C, KIAA1985 ENSG00000169247 SH3 domain and tetratricopeptide repeats 2 5 148923639-149063163 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037683, HPA037684 Uncertain Approved Nucleoplasm
Cytosol Mixed Group enriched 6 cerebral cortex: 3.0;placenta: 2.8;testis: 8.8 cervix, uterine,heart muscle: 0.7 Cell line enhanced RT4: 6.6;SK-MEL-30: 5.9;WM-115: 8.2 +CXCL11 b-R1, H174, I-TAC, IP-9, SCYB11, SCYB9B ENSG00000169248 C-X-C motif chemokine ligand 11 4 76033682-76041415 Predicted secreted proteins Evidence at protein level CAB009921 Uncertain Ovarian cancer:4.31e-7 (favourable), Renal cancer:3.29e-6 (unfavourable), Pancreatic cancer:8.18e-5 (unfavourable) Expressed in all Tissue enhanced appendix: 13.5 lymph node: 11.5 Group enriched 6 BJ hTERT+: 2.4;BJ hTERT+ SV40 Large T+: 4.3;BJ hTERT+ SV40 Large T+ RasG12V: 4.7 +ZRSR2 U2AF1-RS2, U2AF1L2, URP, ZC3H22 ENSG00000169249 Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 X 15790472-15823260 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.87e-5 (unfavourable), Endometrial cancer:8.50e-5 (favourable), Urothelial cancer:2.97e-4 (favourable), Breast cancer:7.96e-4 (favourable) Expressed in all Expressed in all spleen: 34.1 Expressed in all +NMD3 CGI-07 ENSG00000169251 NMD3 ribosome export adaptor 3 161104696-161253532 Predicted intracellular proteins Evidence at protein level HPA035019 Supported Nucleus
Nucleoli Pancreatic cancer:2.03e-5 (unfavourable) Expressed in all Expressed in all prostate: 44.8 Expressed in all +ADRB2 ADRB2R, ADRBR, B2AR, BAR ENSG00000169252 Adrenoceptor beta 2 5 148825245-148828687 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA003431, HPA075322 Uncertain Uncertain Cytosol Renal cancer:3.15e-9 (favourable) Mixed Mixed lung: 16.3 Cell line enhanced hTCEpi: 28.8;hTERT-HME1: 31.6 +B3GALNT1 B3GALT3, beta3Gal-T3, galT3, GLOB, P1 ENSG00000169255 Beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 3 161083883-161105384 Blood group antigen proteins, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041204 Approved Vesicles Expressed in all Mixed thyroid gland: 47.9 Cell line enhanced RT4: 111.0 +GPRIN1 GRIN1, KIAA1893 ENSG00000169258 G protein regulated inducer of neurite outgrowth 1 5 176595802-176610133 Predicted intracellular proteins Evidence at protein level HPA036478, HPA070892 Enhanced Supported Vesicles
Plasma membrane Renal cancer:2.79e-7 (unfavourable), Lung cancer:6.83e-6 (unfavourable) Expressed in all Tissue enriched 7 cerebral cortex: 27.8 duodenum: 3.8 Cell line enhanced HDLM-2: 52.6;SCLC-21H: 70.4 +HSPB3 HSPL27 ENSG00000169271 Heat shock protein family B (small) member 3 5 54455601-54456384 Disease related genes, Predicted intracellular proteins Evidence at protein level Tissue enriched Group enriched 10 heart muscle: 212.2;skeletal muscle: 64.3 esophagus: 14.0 Cell line enhanced BJ hTERT+: 56.3;fHDF/TERT166: 24.5;HSkMC: 9.6 +KCNAB1 AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3 ENSG00000169282 Potassium voltage-gated channel subfamily A member regulatory beta subunit 1 3 156037701-156539138 Predicted intracellular proteins, Transporters Evidence at protein level HPA044550 Approved Tissue enhanced Tissue enhanced prostate: 37.4;thyroid gland: 48.4 seminal vesicle: 26.6 Cell line enhanced hTEC/SVTERT24-B: 5.2 +MRPL1 BM022 ENSG00000169288 Mitochondrial ribosomal protein L1 4 77862520-77952790 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043656 Supported Supported Mitochondria Renal cancer:3.35e-5 (favourable) Expressed in all Expressed in all kidney: 29.5 Expressed in all +SHE ENSG00000169291 Src homology 2 domain containing E 1 154469772-154502113 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037417 Approved Tissue enhanced Mixed testis: 31.9 Group enriched 6 HUVEC TERT2: 42.7;TIME: 11.5 +NR0B1 AHC, AHCH, DAX1, DSS ENSG00000169297 Nuclear receptor subfamily 0 group B member 1 X 30304206-30309598 Cancer-related genes, Disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA061948, HPA067207 Supported Nuclear speckles
Vesicles
Microtubule organizing center Tissue enhanced Group enriched 8 adrenal gland: 27.8;testis: 35.0 ovary: 4.1 Cell line enhanced A549: 51.8;RT4: 14.5;U-87 MG: 7.9 +PGM2 FLJ10983 ENSG00000169299 Phosphoglucomutase 2 4 37826633-37862937 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040676 Uncertain Approved Intermediate filaments Colorectal cancer:2.14e-5 (favourable) Expressed in all Mixed esophagus: 36.5 Expressed in all +STK32A MGC22688, YANK1 ENSG00000169302 Serine/threonine kinase 32A 5 147234963-147387852 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040236 Uncertain Approved Centrosome Tissue enhanced Tissue enhanced adrenal gland: 15.6;thyroid gland: 16.1 cerebral cortex: 7.3 Group enriched 6 RT4: 12.4;SK-MEL-30: 43.0 +IL1RAPL1 IL1R8, IL1RAPL, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2 ENSG00000169306 Interleukin 1 receptor accessory protein like 1 X 28587399-29956723 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 11 cerebral cortex: 5.1 ovary,prostate,seminal vesicle: 0.4 Cell line enhanced WM-115: 2.5 +P2RY12 HORK3, P2Y12, SP1999 ENSG00000169313 Purinergic receptor P2Y12 3 151337380-151384812 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013796, HPA014518 Enhanced Tissue enriched Tissue enriched 6 cerebral cortex: 83.8 lymph node: 13.1 Not detected +C22orf15 FLJ36561, N27C7-3 ENSG00000169314 Chromosome 22 open reading frame 15 22 23763021-23765861 Predicted secreted proteins Evidence at transcript level Endometrial cancer:8.53e-5 (favourable) Tissue enhanced Tissue enriched 15 fallopian tube: 29.3 testis: 1.9 Cell line enhanced AF22: 1.1;BJ hTERT+: 1.5;MOLT-4: 1.0 +OR5AU1 ENSG00000169327 Olfactory receptor family 5 subfamily AU member 1 14 21154865-21156063 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected seminal vesicle: 0.2 Not detected +KIAA1024 ENSG00000169330 KIAA1024 15 79432516-79472290 Predicted membrane proteins Evidence at protein level HPA011545 Uncertain Approved Golgi apparatus Mixed Tissue enriched 11 adrenal gland: 14.0 prostate,salivary gland: 1.2 Cell line enhanced U-138 MG: 9.2 +PDILT PDIA7 ENSG00000169340 Protein disulfide isomerase like, testis expressed 16 20359170-20404737 Predicted secreted proteins Evidence at protein level HPA041913 Approved Not detected Tissue enriched 5 testis: 31.2 stomach: 6.1 Group enriched 6 HBEC3-KT: 9.1;hTCEpi: 7.4;hTERT-HME1: 2.4 +UMOD ENSG00000169344 Uromodulin 16 20333052-20356301 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009446, HPA043420, HPA054721 Enhanced Tissue enriched Tissue enriched 726 kidney: 2392.4 cerebral cortex: 3.2 Not detected +GP2 ZAP75 ENSG00000169347 Glycoprotein 2 16 20309572-20327808 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015739, HPA016668 Enhanced Tissue enriched Tissue enriched 206 pancreas: 7530.3 duodenum: 36.5 Not detected +SLC33A1 ACATN, AT-1, AT1, SPG42 ENSG00000169359 Solute carrier family 33 member 1 3 155821024-155854429 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA042430, HPA060345 Uncertain Approved Nucleus Expressed in all Expressed in all thyroid gland: 67.3 Expressed in all +SNUPN RNUT1, SNURPORTIN-1, Snurportin1 ENSG00000169371 Snurportin 1 15 75598083-75626469 Predicted intracellular proteins Evidence at protein level CAB005004 Approved Supported Nuclear membrane Expressed in all Expressed in all testis: 54.1 Expressed in all +CRADD RAIDD ENSG00000169372 CASP2 and RIPK1 domain containing adaptor with death domain 12 93677375-93894840 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB005337 Uncertain Approved Nucleus
Cytosol Renal cancer:4.04e-9 (favourable), Cervical cancer:9.06e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 32.8 Expressed in all +SIN3A DKFZP434K2235, KIAA0700 ENSG00000169375 SIN3 transcription regulator family member A 15 75369379-75455842 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004506, HPA047213, HPA062123 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all testis: 55.3 Expressed in all +ARL13B ARL2L1, DKFZp761H079, JBTS8 ENSG00000169379 ADP ribosylation factor like GTPase 13B 3 93980139-94055668 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA048926 Enhanced Uncertain Microtubules
Cytosol Expressed in all Mixed thyroid gland: 9.3 Mixed +RNASE2 EDN, RAF3, RNS2 ENSG00000169385 Ribonuclease A family member 2 14 20955452-20956436 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA044983 Enhanced Renal cancer:3.28e-13 (unfavourable) Tissue enriched Tissue enriched 73 bone marrow: 995.8 smooth muscle: 13.6 Group enriched 286 HL-60: 411.9;NB-4: 325.9;THP-1: 920.7;U-937: 968.9 +ELSPBP1 E12, EDDM12, HE12 ENSG00000169393 Epididymal sperm binding protein 1 19 47994651-48025153 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044256, HPA050341 Enhanced Tissue enhanced Tissue enriched 2038 epididymis: 3638.2 testis: 1.7 Cell line enhanced BEWO: 1.5;HMC-1: 9.1;NB-4: 3.7 +RNASE3 ECP, RAF1, RNS3 ENSG00000169397 Ribonuclease A family member 3 14 20891399-20892348 Predicted secreted proteins Evidence at protein level HPA056183 Enhanced Tissue enriched Tissue enriched 300 bone marrow: 572.3 skin: 1.9 Cell line enhanced HL-60: 114.0;THP-1: 41.0;U-937: 225.8 +PTK2 FADK, FAK, FAK1, PPP1R71 ENSG00000169398 Protein tyrosine kinase 2 8 140657900-141002216 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001842, CAB004036, HPA029671 Approved Supported Vesicles
Focal adhesion sites
Cytosol Breast cancer:3.21e-4 (unfavourable), Endometrial cancer:9.11e-4 (unfavourable) Expressed in all Expressed in all placenta: 107.1 Mixed +RSPH10B2 ENSG00000169402 Radial spoke head 10 homolog B2 7 6754109-6799365 Predicted intracellular proteins Evidence at protein level HPA049182 Supported Not detected Group enriched 7 fallopian tube: 16.1;testis: 35.8 parathyroid gland: 3.6 Not detected +PTAFR ENSG00000169403 Platelet activating factor receptor 1 28147166-28193936 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA027543 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Expressed in all Tissue enhanced appendix: 41.1 bone marrow: 26.2 Cell line enhanced HBEC3-KT: 26.0;HMC-1: 113.4 +PTPN9 MEG2 ENSG00000169410 Protein tyrosine phosphatase, non-receptor type 9 15 75463251-75579289 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041922 Approved Approved Vesicles Renal cancer:2.49e-6 (favourable) Expressed in all Expressed in all thyroid gland: 54.8 Expressed in all +RNASE6 RAD1, RNaseK6, RNS6 ENSG00000169413 Ribonuclease A family member k6 14 20781051-20782467 Predicted secreted proteins Evidence at protein level HPA000698 Approved Expressed in all Mixed lymph node: 90.2 Cell line enriched 6 RPMI-8226: 36.0 +NPR1 ANPa, ANPRA, GUCY2A, NPRA ENSG00000169418 Natriuretic peptide receptor 1 1 153678637-153693992 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA031087 Approved Nucleus
Nucleoli
Plasma membrane Pancreatic cancer:2.49e-4 (favourable), Endometrial cancer:3.97e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 72.0;fallopian tube: 58.2 placenta: 25.4 Cell line enriched 6 ASC diff: 107.2 +KCNK9 K2p9.1, TASK-3, TASK3 ENSG00000169427 Potassium two pore domain channel subfamily K member 9 8 139600838-139703056 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Mixed Group enriched 7 adrenal gland: 4.7;cerebral cortex: 4.8 cervix, uterine: 0.7 Cell line enhanced PC-3: 2.0;SCLC-21H: 1.1 +CXCL8 3-10C, AMCF-I, b-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1 ENSG00000169429 C-X-C motif chemokine ligand 8 4 73740506-73743716 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA057179 Supported Renal cancer:3.13e-6 (unfavourable), Cervical cancer:1.18e-5 (unfavourable), Liver cancer:1.19e-5 (unfavourable) Expressed in all Tissue enriched 7 bone marrow: 2076.0 appendix: 293.4 Cell line enriched 6 BJ hTERT+: 3127.1 +SCN9A ETHA, Nav1.7, NE-NA, NENA, PN1 ENSG00000169432 Sodium voltage-gated channel alpha subunit 9 2 166195185-166375993 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB013679, HPA061843 Uncertain Approved Plasma membrane
Actin filaments
Focal adhesion sites Renal cancer:2.30e-5 (unfavourable) Mixed Tissue enhanced testis: 9.1 placenta: 5.9 Cell line enhanced BJ: 20.5;BJ hTERT+: 13.6;HHSteC: 13.7 +RASSF6 ENSG00000169435 Ras association domain family member 6 4 73571550-73620631 Predicted intracellular proteins Evidence at protein level HPA037712 Approved Approved Nucleoplasm
Golgi apparatus Mixed Tissue enhanced stomach: 33.0 rectum: 13.8 Cell line enhanced Daudi: 53.8;RT4: 55.3;U-698: 42.2 +COL22A1 ENSG00000169436 Collagen type XXII alpha 1 chain 8 138588235-138914006 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA024830 Supported Supported Endoplasmic reticulum
Vesicles Lung cancer:2.13e-6 (unfavourable), Glioma:3.62e-4 (unfavourable) Mixed Tissue enhanced adrenal gland: 9.7 prostate: 4.8 Group enriched 5 HDLM-2: 27.1;RT4: 9.7;SCLC-21H: 9.4;U-2 OS: 6.9 +SDC2 CD362, fibroglycan, HSPG, HSPG1, SYND2 ENSG00000169439 Syndecan 2 8 96493351-96611780 CD markers, Predicted membrane proteins Evidence at protein level CAB025123, HPA044416 Uncertain Approved Plasma membrane
Cytosol Expressed in all Expressed in all thyroid gland: 712.7 Cell line enhanced AF22: 646.8;U-138 MG: 309.2 +CD52 CDW52 ENSG00000169442 CD52 molecule 1 26317957-26320523 Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Breast cancer:1.85e-5 (favourable), Endometrial cancer:2.06e-4 (favourable), Head and neck cancer:4.45e-4 (favourable), Renal cancer:5.85e-4 (unfavourable) Expressed in all Tissue enriched 35 epididymis: 43887.5 lymph node: 1251.0 Group enriched 8 Daudi: 505.6;REH: 946.6;U-266/84: 745.1;U-698: 783.6 +MMGT1 EMC5, TMEM32 ENSG00000169446 Membrane magnesium transporter 1 X 135962070-135974063 Predicted membrane proteins Evidence at protein level HPA032037 Approved Renal cancer:1.94e-5 (favourable), Breast cancer:8.54e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 34.5 Expressed in all +SPRR1B GADD33, SPRR1 ENSG00000169469 Small proline rich protein 1B 1 153031202-153032900 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Pancreatic cancer:7.64e-5 (unfavourable), Lung cancer:7.66e-5 (unfavourable), Urothelial cancer:7.28e-4 (unfavourable) Group enriched Tissue enriched 6 esophagus: 2454.9 tonsil: 406.1 Cell line enriched 8 hTCEpi: 263.1 +SPRR1A ENSG00000169474 Small proline rich protein 1A 1 152985231-152985500 Predicted intracellular proteins Evidence at protein level CAB011237 Enhanced Pancreatic cancer:1.03e-4 (unfavourable) Tissue enhanced Tissue enriched 12 esophagus: 9968.1 tonsil: 835.5 Group enriched 6 HaCaT: 21.3;hTCEpi: 49.9;RT4: 21.6 +OR4K14 ENSG00000169484 Olfactory receptor family 4 subfamily K member 14 14 20014260-20015193 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR4K15 OR4K15Q ENSG00000169488 Olfactory receptor family 4 subfamily K member 15 14 19975444-19976659 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA055732 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +TM2D2 BLP1 ENSG00000169490 TM2 domain containing 2 8 38988808-38996824 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA047152, HPA050547 Approved Approved Nucleoplasm
Vesicles
Plasma membrane Colorectal cancer:1.71e-4 (favourable), Breast cancer:7.49e-4 (unfavourable) Expressed in all Expressed in all testis: 51.3 Expressed in all +HTRA4 FLJ90724 ENSG00000169495 HtrA serine peptidase 4 8 38974164-38988662 Enzymes, Predicted secreted proteins Evidence at protein level HPA045402 Enhanced Tissue enhanced Tissue enriched 20 placenta: 94.9 bone marrow: 4.7 Cell line enriched 160 BEWO: 219.1 +PLEKHA2 TAPP2 ENSG00000169499 Pleckstrin homology domain containing A2 8 38901235-38973909 Predicted intracellular proteins Evidence at protein level HPA004706 Approved Uncertain Nucleus
Nuclear bodies
Cytosol Renal cancer:1.95e-6 (unfavourable) Expressed in all Expressed in all lymph node: 91.8 Cell line enhanced Daudi: 113.1 +CLIC4 CLIC4L, DKFZP566G223, H1, huH1, P64H1 ENSG00000169504 Chloride intracellular channel 4 1 24745357-24844324 Predicted intracellular proteins, Transporters Evidence at protein level HPA008019, HPA060804 Enhanced Supported Cytosol Renal cancer:1.48e-5 (favourable), Cervical cancer:8.31e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 398.9 Expressed in all +SLC38A11 AVT2, FLJ39822 ENSG00000169507 Solute carrier family 38 member 11 2 164896186-164955525 Predicted membrane proteins, Transporters Evidence at transcript level HPA043432 Uncertain Renal cancer:2.00e-8 (favourable) Tissue enriched Tissue enhanced epididymis: 47.1;gallbladder: 28.2 seminal vesicle: 23.5 Cell line enriched 8 BJ hTERT+: 202.7 +GPR183 EBI2 ENSG00000169508 G protein-coupled receptor 183 13 99294530-99307405 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA028847, CAB033690 Uncertain Approved Nuclear membrane
Vesicles Cervical cancer:9.77e-4 (favourable) Expressed in all Mixed appendix: 114.8 Group enriched 49 HDLM-2: 144.6;HL-60: 85.1 +CRCT1 C1orf42, NICE-1 ENSG00000169509 Cysteine rich C-terminal 1 1 152514502-152516010 Predicted intracellular proteins Evidence at protein level Pancreatic cancer:7.03e-4 (unfavourable) Tissue enhanced Group enriched 11 esophagus: 84.0;skin: 82.8;tonsil: 17.6 breast: 5.6 Cell line enriched 14 CAPAN-2: 4.5 +CCDC8 3M3, DKFZp564K0322, PPP1R20 ENSG00000169515 Coiled-coil domain containing 8 19 46410372-46413584 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041993 Uncertain Approved Nucleus
Plasma membrane
Cytosol Renal cancer:1.72e-5 (favourable) Mixed Tissue enhanced ovary: 45.3 fallopian tube: 37.6 Cell line enhanced AN3-CA: 20.7;RH-30: 24.3 +METTL15 FLJ33979, METT5D1 ENSG00000169519 Methyltransferase like 15 11 28108248-28527041 Predicted intracellular proteins Evidence at protein level HPA039885 Approved Golgi apparatus
Plasma membrane
Actin filaments Renal cancer:7.95e-5 (favourable) Expressed in all Mixed parathyroid gland: 14.7 Expressed in all +ZNF280A 3'OY11.1, SUHW1, ZNF280, ZNF636 ENSG00000169548 Zinc finger protein 280A 22 22513736-22520270 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA044475 Uncertain Uncertain Nucleoplasm Tissue enhanced Not detected adrenal gland: 0.3 Cell line enhanced BEWO: 1.8;K-562: 7.3;SK-MEL-30: 1.6 +MUC15 ENSG00000169550 Mucin 15, cell surface associated 11 26559033-26572233 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA026110 Approved Tissue enriched Tissue enriched 18 epididymis: 2826.7 thyroid gland: 159.3 Cell line enhanced BEWO: 9.4;K-562: 11.5;SK-BR-3: 15.6;U-266/70: 6.2;U-266/84: 16.2 +CT55 CXorf48, FLJ20527 ENSG00000169551 Cancer/testis antigen 55 X 135156536-135171398 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 31 testis: 6.5 cerebral cortex: 0.2 Cell line enriched 18 K-562: 6.7 +ZEB2 KIAA0569, SIP-1, SIP1, ZFHX1B ENSG00000169554 Zinc finger E-box binding homeobox 2 2 144364364-144524583 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003456 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:6.04e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 99.9 Mixed +GJB1 CMTX, CMTX1, CX32 ENSG00000169562 Gap junction protein beta 1 X 71215194-71225516 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB012994 Uncertain Renal cancer:2.85e-6 (favourable) Tissue enhanced Tissue enhanced liver: 159.4 gallbladder: 59.2 Group enriched 6 Hep G2: 94.2;SK-MEL-30: 123.7 +PCBP1 hnRNP-E1, hnRNP-X, HNRPE1, HNRPX ENSG00000169564 Poly(rC) binding protein 1 2 70087454-70089203 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037113, HPA043803, HPA068497 Supported Enhanced Nuclear speckles
Cytoplasmic bodies Renal cancer:1.71e-5 (favourable) Expressed in all Expressed in all spleen: 284.0 Expressed in all +HINT1 HINT, PKCI-1, PRKCNH1 ENSG00000169567 Histidine triad nucleotide binding protein 1 5 131159027-131171735 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044577 Approved Supported Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all cerebral cortex: 173.9 Expressed in all +DTWD2 FLJ33977 ENSG00000169570 DTW domain containing 2 5 118837322-118988545 Predicted intracellular proteins Evidence at protein level HPA053173, HPA054864 Approved Supported Nuclear bodies Renal cancer:6.09e-5 (favourable), Colorectal cancer:3.16e-4 (favourable) Expressed in all Mixed thyroid gland: 18.7 Mixed +VPREB1 CD179A, VpreB ENSG00000169575 Pre-B lymphocyte 1 22 22244675-22245515 CD markers, Predicted secreted proteins Evidence at protein level HPA055886 Uncertain Not detected Tissue enriched 15 bone marrow: 17.1 tonsil: 1.1 Group enriched 13 Daudi: 5.6;MOLT-4: 13.7;RPMI-8226: 3.1 +CLIC3 ENSG00000169583 Chloride intracellular channel 3 9 136994635-136996803 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA005963 Enhanced Supported Nuclear bodies Renal cancer:1.12e-4 (unfavourable), Urothelial cancer:7.74e-4 (unfavourable) Tissue enhanced Tissue enhanced esophagus: 86.8;thyroid gland: 85.7 skin: 43.5 Cell line enhanced BEWO: 234.7;MCF7: 88.6;T-47d: 100.2;TIME: 70.2 +INO80E CCDC95, FLJ90652 ENSG00000169592 INO80 complex subunit E 16 29995294-30005793 Predicted intracellular proteins Evidence at protein level HPA043146 Approved Supported Nucleoplasm
Nucleoli Expressed in all Expressed in all fallopian tube: 64.2 Expressed in all +BNC1 BNC, HsT19447 ENSG00000169594 Basonuclin 1 15 83255903-83284714 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA063183, HPA066947, HPA077428 Enhanced Nucleoplasm Tissue enhanced Tissue enhanced testis: 56.0 esophagus: 11.8 Cell line enhanced HBEC3-KT: 83.5;hTCEpi: 92.6;hTERT-HME1: 95.2 +DFFB CAD, CPAN, DFF-40, DFF40 ENSG00000169598 DNA fragmentation factor subunit beta 1 3857267-3885429 Predicted intracellular proteins Evidence at protein level CAB004328, HPA052904 Approved Approved Nucleus
Nucleoli Urothelial cancer:6.29e-5 (favourable) Expressed in all Mixed duodenum: 2.9 Mixed +NFU1 CGI-33, HIRIP5, NifU, NIFUC ENSG00000169599 NFU1 iron-sulfur cluster scaffold 2 69395750-69437628 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035826 Uncertain Supported Nucleoplasm
Cytosol Expressed in all Expressed in all adipose tissue: 71.2 Expressed in all +ANTXR1 ATR, FLJ10601, FLJ21776, TEM8 ENSG00000169604 Anthrax toxin receptor 1 2 69013178-69249327 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054785 Uncertain Vesicles Thyroid cancer:1.22e-5 (unfavourable), Cervical cancer:5.76e-4 (unfavourable) Expressed in all Mixed gallbladder: 180.5 Cell line enhanced LHCN-M2: 286.7 +GKN1 AMP18, BRICD1, CA11 ENSG00000169605 Gastrokine 1 2 68974573-68980974 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA047684 Enhanced Pancreatic cancer:1.54e-4 (unfavourable), Urothelial cancer:4.53e-4 (favourable) Tissue enriched Tissue enriched 1189 stomach: 31769.6 placenta: 26.7 Group enriched 11 HaCaT: 5.1;HMC-1: 13.6;MOLT-4: 9.1;NTERA-2: 14.8;REH: 6.0;U-2 OS: 9.9;U-266/70: 7.3 +CKAP2L FLJ40629, radmis ENSG00000169607 Cytoskeleton associated protein 2 like 2 112736607-112764677 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039407, HPA040057, HPA070737 Uncertain Enhanced Mitotic spindle
Cytosol Lung cancer:7.63e-4 (unfavourable) Mixed Tissue enhanced bone marrow: 8.7;testis: 9.6 lymph node: 6.3 Mixed +C15orf40 MGC29937 ENSG00000169609 Chromosome 15 open reading frame 40 15 82988441-83011641 Predicted intracellular proteins Evidence at protein level HPA042980 Approved Approved Nucleus
Cytosol Renal cancer:4.35e-4 (favourable) Expressed in all Expressed in all epididymis: 23.6 Expressed in all +FAM103A1 C15orf18, HsT19360, MGC2560, RAM ENSG00000169612 Family with sequence similarity 103 member A1 15 82986207-82991057 Predicted intracellular proteins Evidence at protein level HPA041923, HPA041948 Enhanced Supported Nucleoplasm Expressed in all Expressed in all placenta: 37.0 Expressed in all +PROKR1 GPR73, GPR73a, PKR1, ZAQ ENSG00000169618 Prokineticin receptor 1 2 68643589-68658247 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA029396 Uncertain Not detected Group enriched 8 adipose tissue: 1.7;adrenal gland: 1.4;epididymis: 4.3 testis: 0.3 Cell line enhanced NTERA-2: 2.0 +APLF C2orf13, MGC47799, Xip1, ZCCHH1 ENSG00000169621 Aprataxin and PNKP like factor 2 68467561-68655862 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029396, HPA034642, HPA034643 Uncertain Supported Nucleoplasm Mixed Mixed skin: 3.3 Mixed +BOLA2B ENSG00000169627 BolA family member 2B 16 30192934-30194306 Predicted intracellular proteins Evidence at protein level HPA045380, HPA046696 Supported Uncertain Nucleus Mixed Expressed in all lymph node: 32.5 Expressed in all +RGPD8 RanBP2alpha, RANBP2L1 ENSG00000169629 RANBP2-like and GRIP domain containing 8 2 112370092-112434488 Predicted intracellular proteins Evidence at protein level HPA045704, HPA049497, HPA051675, HPA067564 Uncertain Uncertain Nuclear membrane
Vesicles Not detected Tissue enriched 5 testis: 31.7 cerebral cortex: 5.8 Cell line enhanced HEL: 14.4 +HIC2 HRG22, KIAA1020, ZBTB30, ZNF907 ENSG00000169635 HIC ZBTB transcriptional repressor 2 22 21417404-21451463 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031884, HPA059399 Uncertain Supported Nucleus Endometrial cancer:7.42e-5 (unfavourable) Tissue enriched Mixed placenta: 8.4 Cell line enhanced BEWO: 66.9;K-562: 113.3 +LUZP1 LUZP ENSG00000169641 Leucine zipper protein 1 1 23084023-23177808 Predicted intracellular proteins Evidence at protein level HPA028506, HPA028542 Enhanced Uncertain Vesicles
Actin filaments
Cytosol Renal cancer:1.46e-7 (favourable), Cervical cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 47.1 Mixed +HEXDC FLJ23825 ENSG00000169660 Hexosaminidase D 17 82418318-82442645 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022834, HPA023379, HPA027844 Uncertain Approved Nucleoli fibrillar center
Mitochondria Urothelial cancer:2.52e-5 (favourable), Head and neck cancer:2.71e-4 (favourable), Pancreatic cancer:5.57e-4 (favourable), Cervical cancer:7.70e-4 (favourable) Expressed in all Expressed in all spleen: 24.4 Expressed in all +DRD5 DRD1B, DRD1L2 ENSG00000169676 Dopamine receptor D5 4 9781680-9784009 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA048930 Supported Not detected Tissue enhanced appendix: 1.7;cerebral cortex: 2.0;stomach: 3.8 testis: 0.8 Not detected +BUB1 BUB1A, BUB1L, hBUB1 ENSG00000169679 BUB1 mitotic checkpoint serine/threonine kinase 2 110637698-110678114 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006123 Supported Nucleoplasm
Cytosol Liver cancer:1.03e-5 (unfavourable), Pancreatic cancer:2.37e-5 (unfavourable), Endometrial cancer:3.65e-4 (unfavourable), Lung cancer:3.94e-4 (unfavourable) Expressed in all Tissue enhanced testis: 69.5 lymph node: 24.1 Mixed +SPNS1 HSpin1, LAT, nrs, PP2030, SPIN1, SPINL ENSG00000169682 Sphingolipid transporter 1 (putative) 16 28974221-28984548 Predicted membrane proteins, Transporters Evidence at protein level HPA041995, HPA042988 Enhanced Approved Nucleoli fibrillar center
Golgi apparatus
Vesicles
Cytosol Mixed Expressed in all parathyroid gland: 37.1 Expressed in all +LRRC45 MGC20806 ENSG00000169683 Leucine rich repeat containing 45 17 82023302-82031151 Predicted intracellular proteins Evidence at protein level HPA023372, HPA023382, HPA024768 Enhanced Supported Nucleoplasm
Plasma membrane
Centrosome
Cytosol Renal cancer:1.54e-4 (unfavourable) Expressed in all Mixed fallopian tube: 8.3 Mixed +CHRNA5 ENSG00000169684 Cholinergic receptor nicotinic alpha 5 subunit 15 78565520-78595269 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054381 Approved Approved Plasma membrane
Focal adhesion sites Lung cancer:3.64e-5 (unfavourable) Mixed Mixed gallbladder: 6.9 Mixed +MT1B MT1, MT1Q ENSG00000169688 Metallothionein 1B 16 56651899-56653204 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enhanced duodenum: 1.3;liver: 3.2 appendix: 0.5 Not detected +CENPX CENP-X, FAAP10, MGC14480, MHF2, STRA13 ENSG00000169689 Centromere protein X 17 82018702-82024107 Predicted intracellular proteins Evidence at protein level Renal cancer:4.62e-4 (unfavourable) Expressed in all Expressed in all prostate: 70.2 Expressed in all +AGPAT2 BSCL, LPAAT-beta ENSG00000169692 1-acylglycerol-3-phosphate O-acyltransferase 2 9 136673143-136687423 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA019544 Uncertain Approved Centrosome Expressed in all Expressed in all adipose tissue: 300.1 Mixed +ASPSCR1 ASPL, ASPS, TUG, UBXD9, UBXN9 ENSG00000169696 ASPSCR1, UBX domain containing tether for SLC2A4 17 81976807-82017406 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026749 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Renal cancer:1.26e-4 (unfavourable), Pancreatic cancer:2.67e-4 (favourable), Head and neck cancer:8.55e-4 (favourable) Expressed in all Expressed in all testis: 21.3 Expressed in all +GP9 CD42a, GPIX ENSG00000169704 Glycoprotein IX platelet 3 129060767-129062406 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level HPA063182 Enhanced Not detected Tissue enhanced bone marrow: 2.9;spleen: 2.7 testis: 1.2 Cell line enriched 19 HEL: 75.1 +FASN FAS, SDR27X1 ENSG00000169710 Fatty acid synthase 17 82078333-82098332 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005192, HPA006461, CAB015417, HPA056108 Enhanced Enhanced Plasma membrane
Cytosol Cervical cancer:1.42e-5 (unfavourable), Renal cancer:7.16e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 290.7 Expressed in all +CNBP CNBP1, DM2, RNF163, ZCCHC22, ZNF9 ENSG00000169714 CCHC-type zinc finger nucleic acid binding protein 3 129169484-129183922 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063097 Supported Nucleus
Cytosol Pancreatic cancer:3.51e-4 (unfavourable) Expressed in all Expressed in all ovary: 474.6 Expressed in all +MT1E MT1, MTD ENSG00000169715 Metallothionein 1E 16 56625475-56627112 Predicted intracellular proteins Evidence at protein level HPA041152 Approved Approved Nucleoplasm Renal cancer:5.06e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 419.6 Cell line enhanced HBEC3-KT: 785.4;LHCN-M2: 689.5;RPTEC TERT1: 700.7;U-2 OS: 539.7 +ACTRT2 Arp-T2, ARPM2, FLJ25424 ENSG00000169717 Actin related protein T2 1 3021483-3022903 Predicted intracellular proteins Evidence at protein level HPA006480, HPA025079 Enhanced Not detected Tissue enriched 1022 testis: 102.2 all non-specific tissues: 0.0 Not detected +DUS1L DUS1, PP3111 ENSG00000169718 Dihydrouridine synthase 1 like 17 82057506-82065887 Predicted intracellular proteins Evidence at protein level HPA023384 Uncertain Approved Plasma membrane Renal cancer:5.89e-5 (unfavourable) Expressed in all Expressed in all skin: 99.0 Expressed in all +GPS1 COPS1, CSN1 ENSG00000169727 G protein pathway suppressor 1 17 82050691-82057470 Plasma proteins, Predicted intracellular proteins Evidence at protein level Ovarian cancer:3.06e-4 (favourable) Expressed in all Expressed in all testis: 77.0 Expressed in all +RFNG ENSG00000169733 RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 17 82047902-82051831 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011564, HPA031673 Uncertain Supported Nucleus Pancreatic cancer:4.81e-4 (favourable) Expressed in all Expressed in all fallopian tube: 19.7 Expressed in all +DCXR DCR, KIDCR, SDR20C1 ENSG00000169738 Dicarbonyl and L-xylulose reductase 17 82035136-82037732 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA023371, HPA023863 Enhanced Uncertain Nucleoli
Microtubules Renal cancer:2.13e-4 (favourable), Pancreatic cancer:4.70e-4 (favourable) Expressed in all Group enriched 6 epididymis: 297.5;kidney: 217.3;liver: 640.9;prostate: 137.5 adipose tissue: 56.7 Expressed in all +ZNF32 KOX30 ENSG00000169740 Zinc finger protein 32 10 43643859-43648856 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA039148, HPA059640 Supported Nucleoplasm
Nuclear bodies Pancreatic cancer:3.02e-4 (favourable), Liver cancer:7.08e-4 (unfavourable) Expressed in all Expressed in all epididymis: 71.8 Mixed +LDB2 CLIM1, LDB1 ENSG00000169744 LIM domain binding 2 4 16501541-16898809 Predicted intracellular proteins Evidence at protein level CAB017544, HPA068634 Supported Supported Nucleus
Nucleoli
Plasma membrane Expressed in all Mixed endometrium: 108.3 Cell line enhanced HAP1: 35.5;HUVEC TERT2: 54.3;U-138 MG: 25.3 +RAC3 ENSG00000169750 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 17 82031624-82034204 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA047820 Uncertain Endometrial cancer:6.21e-5 (unfavourable), Thyroid cancer:4.69e-4 (unfavourable) Expressed in all Mixed testis: 22.7 Expressed in all +NRG4 HRG4 ENSG00000169752 Neuregulin 4 15 75935969-76059795 Predicted membrane proteins Evidence at protein level HPA010957 Uncertain Mixed Tissue enhanced fallopian tube: 1.0;testis: 1.3 stomach: 0.8 Cell line enhanced HeLa: 2.9;HL-60: 1.3;SiHa: 1.2;U-937: 2.1 +LIMS1 PINCH, PINCH1 ENSG00000169756 LIM zinc finger domain containing 1 2 108534355-108687246 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058455, HPA061230 Approved Supported Focal adhesion sites
Cytosol Renal cancer:7.88e-4 (unfavourable) Expressed in all Expressed in all endometrium: 61.1 Expressed in all +TMEM266 C15orf27, FLJ38190 ENSG00000169758 Transmembrane protein 266 15 76059837-76229121 Predicted membrane proteins Evidence at protein level HPA041921, HPA049425 Enhanced Supported Plasma membrane
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 1.9;skeletal muscle: 1.5 placenta: 1.2 Cell line enhanced NTERA-2: 1.0 +NLGN1 KIAA1070 ENSG00000169760 Neuroligin 1 3 173396284-174286644 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006572, HPA006680 Approved Uncertain Nuclear bodies
Plasma membrane Group enriched Tissue enhanced cerebral cortex: 25.4 testis: 12.5 Cell line enhanced fHDF/TERT166: 20.1;HUVEC TERT2: 20.7;RH-30: 25.4;WM-115: 26.7 +TAPT1 FLJ90013 ENSG00000169762 Transmembrane anterior posterior transformation 1 4 16160505-16227410 Disease related genes, Predicted membrane proteins Evidence at protein level HPA042567, HPA048658 Approved Approved Vesicles Urothelial cancer:4.18e-4 (favourable), Pancreatic cancer:5.34e-4 (favourable), Renal cancer:8.52e-4 (favourable), Endometrial cancer:9.75e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 21.5 Expressed in all +UGP2 UGP1, UGPP1 ENSG00000169764 UDP-glucose pyrophosphorylase 2 2 63840940-63891562 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034696, HPA034697, HPA064836 Enhanced Approved Nucleoplasm
Centrosome
Mitochondria Liver cancer:2.50e-5 (favourable) Expressed in all Expressed in all liver: 593.9 Expressed in all +TAS2R1 T2R1, TRB7 ENSG00000169777 Taste 2 receptor member 1 5 9628997-9712378 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA051879 Uncertain Not detected Tissue enriched 40 testis: 13.1 fallopian tube: 0.3 Not detected +LINGO1 FLJ14594, LERN1, LRRN6A ENSG00000169783 Leucine rich repeat and Ig domain containing 1 15 77613027-77820900 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA074653 Enhanced Approved Plasma membrane Renal cancer:3.23e-7 (unfavourable) Expressed in all Tissue enriched 13 cerebral cortex: 130.8 placenta: 9.8 Cell line enhanced AF22: 23.6;AN3-CA: 18.6;HAP1: 31.4;HEK 293: 19.6;NTERA-2: 56.8 +PRY PRY1, PTPN13LY ENSG00000169789 PTPN13-like, Y-linked Y 22490397-22514637 Predicted intracellular proteins Evidence at protein level HPA046366 Uncertain Not detected Not detected epididymis,testis: 0.2 Not detected +RBMY1F MGC33094 ENSG00000169800 RNA binding motif protein, Y-linked, family 1, member F Y 22168542-22182982 Predicted intracellular proteins Evidence at protein level HPA001534, HPA053147 Supported Not detected Tissue enriched 51 testis: 5.0 all non-specific tissues: 0.0 Group enriched 244 U-266/70: 23.8;U-266/84: 24.9 +PRY2 PTPN13LY2 ENSG00000169807 PTPN13-like, Y-linked 2 Y 22071756-22096007 Predicted intracellular proteins Evidence at protein level HPA046366 Uncertain Not detected Not detected testis: 0.1 Not detected +HNRNPF HNRPF ENSG00000169813 Heterogeneous nuclear ribonucleoprotein F 10 43385617-43409166 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016884, HPA069667 Supported Enhanced Nucleoplasm Liver cancer:5.85e-4 (unfavourable) Expressed in all Expressed in all lymph node: 209.6 Expressed in all +BTD ENSG00000169814 Biotinidase 3 15601341-15645822 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA052275 Uncertain Renal cancer:2.60e-9 (favourable) Expressed in all Expressed in all epididymis: 53.0 Mixed +CSGALNACT2 GALNACT-2, GALNACT2, MGC40204, PRO0082 ENSG00000169826 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 10 43138486-43185308 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031540 Approved Approved Endoplasmic reticulum Renal cancer:3.53e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 87.2 Expressed in all +TACR3 NK3R ENSG00000169836 Tachykinin receptor 3 4 103586031-103719816 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA009418 Uncertain Not detected Not detected cerebral cortex: 0.5 Cell line enriched 13 BEWO: 6.9 +GSX1 Gsh-1, GSH1 ENSG00000169840 GS homeobox 1 13 27792643-27794768 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enriched Not detected cerebral cortex: 0.7 Not detected +PCDH7 BH-Pcdh, PPP1R120 ENSG00000169851 Protocadherin 7 4 30720415-31146805 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011866, HPA046521 Uncertain Enhanced Plasma membrane
Cell Junctions Lung cancer:6.46e-5 (unfavourable), Stomach cancer:6.42e-4 (unfavourable) Mixed Mixed cerebral cortex: 46.0 Cell line enhanced RH-30: 116.4;RT4: 51.9 +ROBO1 DUTT1, FLJ21882, SAX3 ENSG00000169855 Roundabout guidance receptor 1 3 78597240-79767815 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013524, HPA052968, HPA074461 Uncertain Enhanced Plasma membrane Liver cancer:9.88e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 32.9 Mixed +ONECUT1 HNF-6, HNF6, HNF6A ENSG00000169856 One cut homeobox 1 15 52756989-52791078 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003457 Enhanced Group enriched Group enriched 6 gallbladder: 8.4;liver: 5.9;pancreas: 2.3;testis: 1.8 bone marrow: 0.7 Cell line enhanced MCF7: 1.7;WM-115: 1.5 +AVEN PDCD12 ENSG00000169857 Apoptosis and caspase activation inhibitor 15 33866227-34039176 Predicted intracellular proteins Evidence at protein level HPA020863 Approved Approved Plasma membrane
Actin filaments
Centrosome Renal cancer:5.29e-10 (unfavourable) Expressed in all Expressed in all smooth muscle: 19.1 Expressed in all +P2RY1 P2Y1 ENSG00000169860 Purinergic receptor P2Y1 3 152834693-152841439 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA015577 Enhanced Renal cancer:2.04e-7 (unfavourable) Mixed Tissue enhanced placenta: 34.0 esophagus: 19.9 Cell line enriched 6 HEL: 38.5 +CTNND2 GT24, NPRAP ENSG00000169862 Catenin delta 2 5 10971840-11904043 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA015077, CAB037339 Enhanced Approved Nucleoplasm
Golgi apparatus
Cell Junctions Tissue enriched Tissue enriched 18 cerebral cortex: 103.2 spleen: 5.6 Cell line enhanced AF22: 19.5;MCF7: 7.1;SK-BR-3: 4.4;U-266/84: 12.6 +TRIM56 RNF109 ENSG00000169871 Tripartite motif containing 56 7 101085439-101097967 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024358 Approved Approved Nucleoplasm
Cytosol Urothelial cancer:2.13e-4 (favourable), Liver cancer:3.87e-4 (unfavourable) Expressed in all Expressed in all spleen: 29.5 Mixed +MUC17 ENSG00000169876 Mucin 17, cell surface associated 7 101020072-101058745 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA031634 Enhanced Group enriched Group enriched 8 duodenum: 21.8;small intestine: 42.5 rectum: 3.8 Not detected +AHSP EDRF, ERAF ENSG00000169877 Alpha hemoglobin stabilizing protein 16 31527864-31528803 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040940 Enhanced Not detected Tissue enriched 26 bone marrow: 881.3 placenta: 34.3 Cell line enhanced hTCEpi: 2.0;K-562: 1.1 +WNT10B SHFM6, WNT-12 ENSG00000169884 Wnt family member 10B 12 48965340-48971763 Disease related genes, Predicted secreted proteins Evidence at protein level HPA055048, HPA062539 Enhanced Approved Golgi apparatus Mixed Tissue enhanced cerebral cortex: 11.6 skin: 3.0 Cell line enhanced T-47d: 7.6 +CALML6 CAGLP ENSG00000169885 Calmodulin like 6 1 1914827-1917296 Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level Not detected Tissue enriched 9 skeletal muscle: 37.6 esophagus: 4.2 Cell line enhanced AN3-CA: 1.6 +REPS2 POB1 ENSG00000169891 RALBP1 associated Eps domain containing 2 X 16946691-17153280 Predicted secreted proteins Evidence at protein level HPA000565, HPA026073 Uncertain Pancreatic cancer:3.24e-4 (unfavourable), Renal cancer:4.08e-4 (favourable), Urothelial cancer:4.56e-4 (favourable), Liver cancer:5.36e-4 (favourable) Expressed in all Mixed cerebral cortex: 28.8 Cell line enhanced HDLM-2: 27.9;Karpas-707: 8.4;RH-30: 8.1 +MUC3A MUC3 ENSG00000169894 Mucin 3A, cell surface associated 7 100949555-100968346 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010871 Uncertain Tissue enhanced Tissue enhanced duodenum: 41.6;gallbladder: 21.8;small intestine: 37.1 rectum: 13.1 Cell line enhanced CACO-2: 6.0;CAPAN-2: 2.1;U-2 OS: 1.4 +SYAP1 FLJ14495, PRO3113 ENSG00000169895 Synapse associated protein 1 X 16719632-16765336 Predicted secreted proteins Evidence at protein level HPA000175, HPA000882, HPA048047 Approved Enhanced Nucleoplasm
Golgi apparatus
Cytosol Ovarian cancer:3.18e-4 (favourable) Expressed in all Expressed in all adrenal gland: 33.5 Expressed in all +ITGAM CD11B, CR3A, MAC-1 ENSG00000169896 Integrin subunit alpha M 16 31259990-31332892 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002274, CAB025091, CAB072870 Enhanced Renal cancer:6.93e-5 (unfavourable), Liver cancer:3.43e-4 (unfavourable), Testis cancer:6.93e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 130.2 appendix: 36.3 Cell line enhanced HMC-1: 47.6;NB-4: 12.7;U-937: 18.8 +PYDC1 ASC2, POP1 ENSG00000169900 Pyrin domain containing 1 16 31215962-31217359 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 8 skin: 4.3 cerebral cortex: 0.5 Not detected +TPST1 TANGO13A ENSG00000169902 Tyrosylprotein sulfotransferase 1 7 66205199-66420543 Enzymes, Predicted secreted proteins Evidence at protein level HPA047415, HPA061837 Approved Approved Golgi apparatus Renal cancer:8.16e-6 (unfavourable), Urothelial cancer:3.73e-5 (unfavourable), Stomach cancer:8.78e-4 (unfavourable) Expressed in all Mixed gallbladder: 55.7 Mixed +TM4SF4 il-TMP ENSG00000169903 Transmembrane 4 L six family member 4 3 149473974-149503281 Predicted membrane proteins, Transporters Evidence at protein level HPA046430 Enhanced Approved Plasma membrane
Cytosol Group enriched Group enriched 34 duodenum: 579.6;gallbladder: 1319.6;liver: 346.9;small intestine: 504.0 stomach: 20.2 Group enriched 6 A549: 19.4;RPTEC TERT1: 24.4 +TOR1AIP2 IFRG15, LULL1, NET9 ENSG00000169905 Torsin 1A interacting protein 2 1 179839967-179877803 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051849, HPA058348, HPA070542 Uncertain Enhanced Endoplasmic reticulum Renal cancer:2.29e-4 (unfavourable) Expressed in all Expressed in all placenta: 34.1 Expressed in all +S100G CABP1, CABP9K, CALB3 ENSG00000169906 S100 calcium binding protein G X 16650158-16654670 Predicted intracellular proteins Evidence at protein level CAB017688, HPA055873 Enhanced Group enriched Tissue enriched 11 duodenum: 240.6 small intestine: 22.6 Cell line enhanced RPMI-8226: 1.6 +TM4SF1 L6, M3S1 ENSG00000169908 Transmembrane 4 L six family member 1 3 149369022-149377865 Predicted membrane proteins Evidence at protein level CAB002760, HPA002823 Uncertain Urothelial cancer:3.43e-6 (unfavourable), Renal cancer:2.24e-4 (unfavourable), Pancreatic cancer:4.01e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 327.5 Cell line enhanced CAPAN-2: 539.1;LHCN-M2: 495.4 +OTUD3 DUBA4, KIAA0459 ENSG00000169914 OTU deubiquitinase 3 1 19882513-19912945 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028543, HPA028544 Approved Approved Nucleoplasm
Intermediate filaments
Cytosol Expressed in all Mixed testis: 19.4 Expressed in all +OTUD7A C15orf16, CEZANNE2, OTUD7 ENSG00000169918 OTU deubiquitinase 7A 15 31475398-31870789 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA044554 Uncertain Approved Nucleoli
Cytosol Mixed Tissue enhanced cerebral cortex: 13.5 testis: 5.1 Cell line enhanced SCLC-21H: 6.3;SH-SY5Y: 2.7 +GUSB ENSG00000169919 Glucuronidase beta 7 65960684-65982314 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA036322, HPA036323 Approved Supported Vesicles Expressed in all Expressed in all breast: 95.9 Expressed in all +BRD3 KIAA0043, ORFX, RING3L ENSG00000169925 Bromodomain containing 3 9 134030305-134068535 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051830 Approved Approved Nuclear bodies Renal cancer:2.71e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 19.6 Expressed in all +KLF13 BTEB3, FKLF-2, NSLP1, RFLAT-1 ENSG00000169926 Kruppel like factor 13 15 31326855-31435665 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Renal cancer:2.37e-9 (favourable) Expressed in all Expressed in all bone marrow: 37.8 Mixed +FRMPD4 KIAA0316, PDZD10, PDZK10 ENSG00000169933 FERM and PDZ domain containing 4 X 12138466-12724523 Disease related genes, Predicted intracellular proteins Evidence at protein level Not detected Group enriched 31 cerebral cortex: 17.7;parathyroid gland: 30.1 heart muscle: 0.7 Cell line enhanced LHCN-M2: 3.5;U-2197: 6.0;U-266/70: 4.5 +ZFPM2 FOG2, hFOG-2, ZC2HC11B, ZNF89B ENSG00000169946 Zinc finger protein, FOG family member 2 8 104590733-105804532 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004094 Approved Supported Nucleoplasm Mixed Tissue enhanced ovary: 41.0 smooth muscle: 26.3 Cell line enhanced AF22: 6.4;BJ hTERT+: 11.5;HHSteC: 8.3;HUVEC TERT2: 9.0 +ZNF764 MGC13138 ENSG00000169951 Zinc finger protein 764 16 30553764-30558498 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003203 Uncertain Approved Cytosol Endometrial cancer:6.84e-4 (favourable) Expressed in all Mixed testis: 6.0 Expressed in all +HSFY2 FLJ25453 ENSG00000169953 Heat shock transcription factor, Y-linked 2 Y 18731440-18828662 Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Tissue enriched 200 testis: 24.7 kidney: 0.1 Not detected +ZNF747 MGC2474 ENSG00000169955 Zinc finger protein 747 16 30530367-30535347 Predicted intracellular proteins Evidence at protein level HPA003203, HPA069173 Uncertain Approved Centrosome
Cytosol Pancreatic cancer:4.46e-4 (favourable), Cervical cancer:6.53e-4 (favourable) Expressed in all Mixed parathyroid gland: 15.6 Mixed +ZNF768 FLJ23436 ENSG00000169957 Zinc finger protein 768 16 30524001-30526821 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024630, HPA066512 Supported Approved Nucleus
Vesicles Renal cancer:9.30e-6 (favourable), Urothelial cancer:6.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 55.9 Expressed in all +TAS1R3 T1R3 ENSG00000169962 Taste 1 receptor member 3 1 1331314-1335306 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA053439 Uncertain Mixed Group enriched 5 epididymis: 14.9;salivary gland: 3.3 appendix: 1.7 Cell line enhanced Karpas-707: 1.8 +TMEM42 MGC29956 ENSG00000169964 Transmembrane protein 42 3 44861869-44865670 Predicted membrane proteins Evidence at transcript level HPA052569 Uncertain Uncertain Nucleoplasm
Nucleoli Renal cancer:1.10e-5 (favourable), Breast cancer:5.23e-4 (favourable) Expressed in all Expressed in all epididymis: 12.8 Mixed +MAP3K2 MEKK2, MEKK2B ENSG00000169967 Mitogen-activated protein kinase kinase kinase 2 2 127298730-127388465 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021540 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 29.8 Expressed in all +PUSL1 FLJ90811 ENSG00000169972 Pseudouridylate synthase-like 1 1 1308567-1311677 Predicted intracellular proteins Evidence at protein level HPA032057, HPA039999 Uncertain Enhanced Vesicles Renal cancer:1.62e-5 (unfavourable), Liver cancer:1.33e-4 (unfavourable) Expressed in all Expressed in all skin: 9.1 Expressed in all +SF3B5 MGC3133, SF3b10, Ysf3 ENSG00000169976 Splicing factor 3b subunit 5 6 144094881-144095573 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054408 Approved Enhanced Nucleoplasm Expressed in all Expressed in all fallopian tube: 204.2 Expressed in all +ZNF35 HF.10, HF10, Zfp105 ENSG00000169981 Zinc finger protein 35 3 44648727-44660791 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051859, HPA054738 Uncertain Approved Nucleoplasm Expressed in all Mixed testis: 9.2 Mixed +TIGD4 ENSG00000169989 Tigger transposable element derived 4 4 152769354-152779764 Predicted intracellular proteins Evidence at protein level HPA035649 Approved Approved Nucleoplasm
Cytosol Mixed Tissue enhanced testis: 8.6 fallopian tube: 3.2 Cell line enhanced U-266/70: 3.4;U-266/84: 6.5 +IFFO2 ENSG00000169991 Intermediate filament family orphan 2 1 18904281-18956686 Predicted intracellular proteins Evidence at transcript level HPA015987, HPA064603 Approved Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all skin: 72.4 Cell line enhanced HDLM-2: 129.1 +NLGN2 KIAA1366 ENSG00000169992 Neuroligin 2 17 7404874-7419860 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055321, HPA069278 Enhanced Approved Mitochondria Renal cancer:3.44e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 40.7 endometrium: 21.8 Cell line enhanced AF22: 43.3 +MYO7B ENSG00000169994 Myosin VIIB 2 127535802-127637729 Predicted intracellular proteins Evidence at protein level HPA039131 Enhanced Renal cancer:1.25e-4 (favourable) Group enriched Tissue enhanced duodenum: 113.9;small intestine: 92.1 colon: 35.2 Cell line enriched 17 MOLT-4: 228.8 +CHD3 Mi-2a, Mi2-ALPHA, ZFH ENSG00000170004 Chromodomain helicase DNA binding protein 3 17 7884806-7912760 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043368, HPA076524 Supported Approved Nucleus
Nucleoli
Microtubule organizing center Endometrial cancer:7.68e-5 (favourable), Colorectal cancer:2.43e-4 (unfavourable), Pancreatic cancer:8.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 85.1 Expressed in all +TMEM154 FLJ32028 ENSG00000170006 Transmembrane protein 154 4 152618632-152680165 Predicted membrane proteins Evidence at protein level HPA019184, HPA055411 Uncertain Approved Nucleoplasm
Nuclear membrane Mixed Tissue enhanced esophagus: 64.3;skin: 69.5 tonsil: 24.1 Cell line enhanced HMC-1: 62.0 +MYRIP DKFZp586F1018, exophilin-8, MyRIP, SLAC2-C, SLAC2C ENSG00000170011 Myosin VIIA and Rab interacting protein 3 39808914-40260321 Predicted intracellular proteins Evidence at protein level HPA006433 Approved Nucleus
Nucleoli
Golgi apparatus Renal cancer:3.96e-8 (favourable) Mixed Tissue enhanced cerebral cortex: 20.6 spleen: 9.9 Cell line enhanced HAP1: 4.2;HUVEC TERT2: 13.0;SCLC-21H: 3.8;SH-SY5Y: 10.0 +ALCAM CD166, MEMD ENSG00000170017 Activated leukocyte cell adhesion molecule 3 105366909-105576900 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002148, HPA010926 Approved Renal cancer:3.15e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 471.5 lung: 111.2 Cell line enhanced U-138 MG: 467.1 +YWHAG PPP1R170 ENSG00000170027 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma 7 76326794-76359031 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013274, CAB018389, HPA026918 Approved Supported Renal cancer:4.01e-4 (unfavourable), Cervical cancer:4.53e-4 (unfavourable), Lung cancer:5.34e-4 (unfavourable), Pancreatic cancer:7.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 611.5 Expressed in all +UBE2E3 UbcH9 ENSG00000170035 Ubiquitin conjugating enzyme E2 E3 2 180967248-181076585 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003303, HPA030445 Approved Pancreatic cancer:1.78e-5 (unfavourable), Head and neck cancer:8.08e-5 (unfavourable), Liver cancer:9.11e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 131.8 Expressed in all +CNTROB LIP8, PP1221 ENSG00000170037 Centrobin, centriole duplication and spindle assembly protein 17 7932101-7949918 Predicted intracellular proteins Evidence at protein level HPA023319, HPA023320, HPA023321, HPA023325 Approved Supported Centrosome
Cytosol Liver cancer:9.88e-4 (unfavourable) Expressed in all Expressed in all testis: 91.4 Expressed in all +TRAPPC1 BET5, MUM2 ENSG00000170043 Trafficking protein particle complex 1 17 7930345-7932123 Predicted intracellular proteins Evidence at protein level HPA052398 Approved Expressed in all Expressed in all placenta: 165.1 Expressed in all +ZPLD1 ENSG00000170044 Zona pellucida like domain containing 1 3 102099244-102479841 Predicted membrane proteins Evidence at transcript level HPA077519 Approved Nucleoplasm Mixed Tissue enhanced gallbladder: 3.5;testis: 1.3 duodenum: 0.9 Cell line enriched 8 RPTEC TERT1: 5.0 +KCNAB3 AKR6A9, KCNA3B ENSG00000170049 Potassium voltage-gated channel subfamily A regulatory beta subunit 3 17 7921859-7929803 Predicted intracellular proteins Evidence at protein level HPA077993 Approved Mitochondria Mixed Tissue enhanced endometrium: 14.6;smooth muscle: 8.6 cerebral cortex: 4.7 Cell line enhanced REH: 11.9 +SERPINA9 CENTERIN, GCET1, SERPINA11b ENSG00000170054 Serpin family A member 9 14 94462717-94479689 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Group enriched 10 appendix: 17.1;lymph node: 50.4;tonsil: 66.3 epididymis: 4.5 Cell line enriched 49 Daudi: 50.2 +FAM153A NY-REN-7 ENSG00000170074 Family with sequence similarity 153 member A 5 177707981-177783398 Predicted intracellular proteins Evidence at transcript level HPA042585, HPA044022, HPA046691, HPA052337, HPA055498 Uncertain Not detected Tissue enhanced testis: 13.8 ovary: 2.8 Not detected +GPR37L1 ETBR-LP-2 ENSG00000170075 G protein-coupled receptor 37 like 1 1 202122858-202133592 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA064454 Enhanced Tissue enriched Tissue enriched 65 cerebral cortex: 34.1 seminal vesicle: 0.5 Cell line enhanced HaCaT: 1.1;MCF7: 1.1;T-47d: 3.6 +SIMC1 C5orf25, FLJ44216, OOMA1, PLEIAD ENSG00000170085 SUMO interacting motifs containing 1 5 176238367-176345991 Predicted intracellular proteins Evidence at protein level HPA037889, HPA037890 Uncertain Supported Nucleus
Nucleoli fibrillar center Endometrial cancer:2.32e-6 (unfavourable), Glioma:1.41e-4 (unfavourable) Expressed in all Tissue enhanced testis: 71.8 ovary: 58.7 Mixed +TMEM192 FLJ38482 ENSG00000170088 Transmembrane protein 192 4 165070608-165208549 Predicted membrane proteins, Transporters Evidence at protein level HPA014717, HPA024110 Enhanced Enhanced Nucleoplasm
Endosomes
Lysosomes Renal cancer:2.33e-14 (favourable), Breast cancer:9.52e-4 (unfavourable) Expressed in all Expressed in all kidney: 51.0 Expressed in all +HMP19 ENSG00000170091 HMP19 protein 5 174045604-174243501 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046531, HPA056191 Enhanced Supported Golgi apparatus Tissue enriched Tissue enriched 7 cerebral cortex: 288.5 adrenal gland: 42.0 Group enriched 84 SCLC-21H: 45.2;SH-SY5Y: 65.3 +SPDYE5 ENSG00000170092 Speedy/RINGO cell cycle regulator family member E5 7 75493625-75504304 Predicted intracellular proteins Evidence at protein level HPA051750 Approved Mixed Tissue enhanced testis: 4.8 skin: 2.3 Mixed +SERPINA6 CBG ENSG00000170099 Serpin family A member 6 14 94304248-94323394 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA017864 Approved Endometrial cancer:6.96e-5 (favourable) Tissue enriched Tissue enriched 6 liver: 217.2 gallbladder: 33.9 Cell line enriched 15 T-47d: 583.2 +ZNF778 FLJ31875 ENSG00000170100 Zinc finger protein 778 16 89217703-89237071 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052057, HPA057151 Uncertain Supported Nucleus
Nuclear bodies Mixed Mixed parathyroid gland: 15.1 Mixed +NIPA1 MGC35570, SPG6 ENSG00000170113 Non imprinted in Prader-Willi/Angelman syndrome 1 15 22773063-22829791 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA023269 Uncertain Expressed in all Tissue enhanced cerebral cortex: 38.2 parathyroid gland: 16.8 Mixed +FOXD4 FKHL9, FOXD4a, FREAC5 ENSG00000170122 Forkhead box D4 9 116231-118204 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA012836 Uncertain Approved Nucleus Mixed Not detected testis: 0.8 Cell line enhanced THP-1: 2.9 +GPR25 ENSG00000170128 G protein-coupled receptor 25 1 200872955-200874178 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced stomach: 1.7 appendix,lung: 0.6 Cell line enriched 6 U-266/70: 1.0 +UBE2E1 UbcH6 ENSG00000170142 Ubiquitin conjugating enzyme E2 E1 3 23805903-23891316 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030445, CAB073413 Approved Approved Nucleoplasm Liver cancer:9.97e-7 (unfavourable) Expressed in all Expressed in all placenta: 119.1 Expressed in all +HNRNPA3 HNRPA3 ENSG00000170144 Heterogeneous nuclear ribonucleoprotein A3 2 177212563-177223958 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001666, HPA005812, HPA066381 Supported Enhanced Nucleoplasm Renal cancer:9.57e-7 (unfavourable), Liver cancer:2.95e-5 (unfavourable), Cervical cancer:4.87e-4 (favourable) Expressed in all Expressed in all endometrium: 309.7 Expressed in all +SIK2 DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2 ENSG00000170145 Salt inducible kinase 2 11 111602391-111730853 Enzymes, Predicted membrane proteins Evidence at protein level HPA016026 Approved Approved Golgi apparatus Renal cancer:1.17e-9 (favourable), Liver cancer:4.93e-4 (favourable) Expressed in all Expressed in all adipose tissue: 32.1 Expressed in all +RNF150 KIAA1214 ENSG00000170153 Ring finger protein 150 4 140859807-141212877 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA037987 Uncertain Breast cancer:1.41e-4 (favourable) Mixed Mixed endometrium,fallopian tube: 21.3 Cell line enhanced fHDF/TERT166: 21.9;SH-SY5Y: 42.3 +CCDC144A FLJ43983, KIAA0565 ENSG00000170160 Coiled-coil domain containing 144A 17 16689537-16777881 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA022996, HPA047220, HPA047851 Approved Approved Nucleoplasm
Vesicles Not detected Tissue enhanced testis: 16.6 endometrium: 6.1 Mixed +VGLL2 ENSG00000170162 Vestigial like family member 2 6 117265558-117273565 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 13 skeletal muscle: 45.1 heart muscle: 3.5 Group enriched 6 RH-30: 13.5;U-2 OS: 5.0 +HOXD4 HOX4, HOX4B ENSG00000170166 Homeobox D4 2 176151222-176153226 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054383, HPA070349 Approved Enhanced Nucleus
Cell Junctions Tissue enhanced Tissue enhanced endometrium: 23.6;epididymis: 22.9 fallopian tube: 15.5 Cell line enhanced EFO-21: 11.0;HEK 293: 25.9;RPTEC TERT1: 15.6 +CHRNB1 CHRNB ENSG00000170175 Cholinergic receptor nicotinic beta 1 subunit 17 7445061-7457707 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA005822, CAB011200 Approved Expressed in all Expressed in all skeletal muscle: 21.9 Cell line enhanced LHCN-M2: 28.7;RH-30: 68.7 +HOXD12 HOX4H ENSG00000170178 Homeobox D12 2 176099730-176101193 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059444 Uncertain Not detected Tissue enhanced colon: 1.0;rectum: 1.1;seminal vesicle: 1.8 prostate: 0.8 Cell line enhanced REH: 2.3 +GYPA CD235a, GPA, MN, MNS ENSG00000170180 Glycophorin A (MNS blood group) 4 144109303-144140751 Blood group antigen proteins, CD markers, Predicted membrane proteins Evidence at protein level CAB002658, HPA014811 Enhanced Not detected Tissue enriched 16 bone marrow: 84.6 placenta: 5.4 Group enriched 264 HEL: 127.3;K-562: 31.3 +USP38 HP43.8KD, KIAA1891 ENSG00000170185 Ubiquitin specific peptidase 38 4 143184917-143223830 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036990, HPA047948 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.20e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 14.1 Expressed in all +SLC16A5 MCT5, MCT6 ENSG00000170190 Solute carrier family 16 member 5 17 75087727-75106162 Predicted membrane proteins, Transporters Evidence at transcript level Expressed in all Mixed duodenum: 34.5 Cell line enhanced A549: 59.5;RPTEC TERT1: 52.1;RT4: 111.4 +NANP C20orf147, dJ694B14.3, HDHD4, MGC26833 ENSG00000170191 N-acetylneuraminic acid phosphatase 20 25612935-25624175 Enzymes, Predicted intracellular proteins Evidence at protein level HPA050342 Uncertain Approved Nuclear membrane Liver cancer:9.01e-6 (unfavourable) Expressed in all Mixed testis: 4.9 Expressed in all +ANKK1 X-kinase ENSG00000170209 Ankyrin repeat and kinase domain containing 1 11 113387791-113400418 Enzymes, Predicted intracellular proteins Evidence at protein level HPA012813 Uncertain Mixed Tissue enhanced skin: 4.2 fallopian tube: 1.3 Cell line enhanced hTCEpi: 1.5 +ADRA1B ENSG00000170214 Adrenoceptor alpha 1B 5 159916783-159972544 Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA074416 Supported Plasma membrane Renal cancer:1.40e-6 (unfavourable), Thyroid cancer:3.19e-5 (favourable), Endometrial cancer:6.00e-5 (unfavourable), Ovarian cancer:2.67e-4 (favourable), Glioma:6.07e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 14.8;spleen: 17.0 ovary: 4.8 Cell line enhanced EFO-21: 12.8;TIME: 10.9;U-2 OS: 9.6 +ADPRM C17orf48, MDS006 ENSG00000170222 ADP-ribose/CDP-alcohol diphosphatase, manganese dependent 17 10697594-10711233 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023265, HPA023820 Approved Endometrial cancer:2.38e-5 (favourable), Cervical cancer:1.69e-4 (favourable) Expressed in all Expressed in all prostate: 16.0 Expressed in all +FABP6 I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP ENSG00000170231 Fatty acid binding protein 6 5 160187367-160238735 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012601, CAB024713 Enhanced Renal cancer:4.35e-9 (unfavourable) Mixed Tissue enriched 49 small intestine: 4217.5 fallopian tube: 86.2 Cell line enhanced Daudi: 22.1;EFO-21: 26.9;HDLM-2: 12.3;U-2197: 11.6 +PWWP2A KIAA1935 ENSG00000170234 PWWP domain containing 2A 5 160061801-160119423 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA046733, HPA058233 Uncertain Supported Nucleoplasm
Focal adhesion sites Urothelial cancer:3.51e-4 (favourable), Renal cancer:3.70e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 15.4 Expressed in all +USP50 ENSG00000170236 Ubiquitin specific peptidase 50 15 50500562-50546708 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA039470 Uncertain Not detected Tissue enriched 18 testis: 1.8 all non-specific tissues: 0.0 Not detected +USP47 ENSG00000170242 Ubiquitin specific peptidase 47 11 11841423-11959323 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029286, HPA029289 Supported Approved Intermediate filaments Expressed in all Expressed in all parathyroid gland: 75.4 Expressed in all +PDCD6IP AIP1, Alix, Hp95 ENSG00000170248 Programmed cell death 6 interacting protein 3 33798352-33869707 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA011905, CAB016212 Approved Enhanced Cytosol Renal cancer:3.90e-9 (favourable), Colorectal cancer:1.16e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 64.1 Expressed in all +MRGPRX1 MRGX1 ENSG00000170255 MAS related GPR family member X1 11 18933813-18939507 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF212 C2H2-150 ENSG00000170260 Zinc finger protein 212 7 149239651-149255609 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049807, HPA054178 Uncertain Supported Nucleus Expressed in all Expressed in all testis: 15.1 Expressed in all +MRAP B27, C21orf61, FALP ENSG00000170262 Melanocortin 2 receptor accessory protein 21 32291813-32314784 Disease related genes, Predicted membrane proteins Evidence at protein level HPA011024 Uncertain Not detected Group enriched 8 adipose tissue: 52.7;adrenal gland: 65.2 breast: 7.5 Cell line enhanced Hep G2: 1.0;HSkMC: 1.2 +FAM161A FLJ13305, RP28 ENSG00000170264 Family with sequence similarity 161 member A 2 61824854-61854143 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA032119 Enhanced Endometrial cancer:9.02e-4 (unfavourable) Mixed Tissue enhanced testis: 10.0 fallopian tube: 6.4 Mixed +ZNF282 HUB1 ENSG00000170265 Zinc finger protein 282 7 149195485-149226248 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024374 Supported Approved Nucleoplasm
Cytosol Liver cancer:3.03e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine,fallopian tube: 14.9 Expressed in all +GLB1 EBP, ELNR1 ENSG00000170266 Galactosidase beta 1 3 32996608-33097230 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB008382, HPA040610, HPA069503 Enhanced Supported Golgi apparatus
Vesicles Renal cancer:1.14e-5 (favourable) Expressed in all Expressed in all epididymis: 122.5 Cell line enriched 5 BEWO: 804.9 +GON7 C14orf142 ENSG00000170270 GON7, KEOPS complex subunit homolog 14 93202894-93207094 Predicted intracellular proteins Evidence at protein level HPA051832 Approved Approved Nucleus
Nucleoli Liver cancer:1.53e-5 (unfavourable), Renal cancer:3.08e-4 (favourable) Expressed in all Mixed fallopian tube: 31.2 Expressed in all +FAXDC2 C5orf4, FLJ13758 ENSG00000170271 Fatty acid hydroxylase domain containing 2 5 154818491-154859252 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Renal cancer:9.71e-10 (favourable), Liver cancer:3.87e-5 (favourable) Expressed in all Tissue enriched 6 parathyroid gland: 388.2 ovary: 66.6 Cell line enhanced ASC diff: 22.0 +CRTAP CASP, LEPREL3, P3H5 ENSG00000170275 Cartilage associated protein 3 33113979-33147773 Disease related genes, Predicted secreted proteins Evidence at protein level HPA043598, HPA044150 Approved Approved Intermediate filaments
Actin filaments
Cytosol Expressed in all Expressed in all cervix, uterine: 197.9 Expressed in all +HSPB2 Hs.78846, MKBP ENSG00000170276 Heat shock protein family B (small) member 2 11 111912242-111914093 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced heart muscle: 36.6 skeletal muscle: 25.0 Cell line enhanced ASC diff: 13.8;fHDF/TERT166: 21.7;HSkMC: 6.9;LHCN-M2: 13.3;U-138 MG: 11.8 +C7orf33 ENSG00000170279 Chromosome 7 open reading frame 33 7 148590565-148615860 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.3 Cell line enriched 26 SCLC-21H: 2.6 +CNGB3 ACHM1, ACHM3, RMCH ENSG00000170289 Cyclic nucleotide gated channel beta 3 8 86553977-86743675 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA057244 Enhanced Not detected Tissue enhanced bone marrow: 2.7;testis: 3.9 fallopian tube: 2.1 Cell line enriched 19 SCLC-21H: 23.7 +SLN MGC12301, MGC125854, MGC125855 ENSG00000170290 Sarcolipin 11 107707378-107719693 Predicted membrane proteins, Transporters Evidence at protein level CAB011628 Approved Microtubules Renal cancer:3.52e-9 (unfavourable) Group enriched Tissue enriched 17 skeletal muscle: 2802.0 heart muscle: 162.9 Cell line enhanced BEWO: 1.1;HSkMC: 1.8;PC-3: 1.0;U-2 OS: 1.2 +ELP5 C17orf81, DERP6 ENSG00000170291 Elongator acetyltransferase complex subunit 5 17 7251416-7259940 Predicted intracellular proteins Evidence at protein level HPA023279 Uncertain Supported Cytosol Pancreatic cancer:2.62e-4 (favourable) Expressed in all Expressed in all testis: 173.3 Expressed in all +CMTM8 CKLFSF8 ENSG00000170293 CKLF like MARVEL transmembrane domain containing 8 3 32238679-32370325 Predicted membrane proteins Evidence at protein level HPA055077, HPA073258 Approved Approved Nucleoplasm Renal cancer:2.80e-4 (favourable) Expressed in all Mixed placenta: 24.8 Cell line enhanced BEWO: 199.8 +GABARAP ATG8A, MM46 ENSG00000170296 GABA type A receptor-associated protein 17 7240014-7242770 Predicted intracellular proteins, Transporters Evidence at protein level HPA065883 Approved Vesicles Pancreatic cancer:9.52e-5 (favourable) Expressed in all Expressed in all epididymis: 763.1 Expressed in all +LGALS9B ENSG00000170298 Galectin 9B 17 20449395-20467539 Predicted intracellular proteins Evidence at protein level HPA046876, HPA047218 Approved Uncertain Cytosol Mixed Tissue enhanced gallbladder: 11.7;rectum: 11.8;stomach: 28.8 colon: 7.5 Group enriched 7 CAPAN-2: 7.5;U-937: 2.2 +STX8 CARB ENSG00000170310 Syntaxin 8 17 9250471-9576591 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001540 Approved Uncertain Nuclear bodies
Golgi apparatus
Actin filaments
Cytosol Expressed in all Expressed in all testis: 96.6 Expressed in all +CDK1 CDC2, CDC28A ENSG00000170312 Cyclin dependent kinase 1 10 60778331-60794852 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA003387, CAB003799 Enhanced Enhanced Nucleus
Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.10e-6 (unfavourable), Pancreatic cancer:4.15e-6 (unfavourable), Lung cancer:7.88e-4 (unfavourable), Cervical cancer:8.81e-4 (favourable) Expressed in all Mixed lymph node: 47.5 Expressed in all +UBB FLJ25987, MGC8385 ENSG00000170315 Ubiquitin B 17 16380798-16382745 Predicted intracellular proteins Evidence at protein level CAB013048, HPA041344, HPA049132 Supported Renal cancer:1.07e-4 (favourable) Expressed in all Expressed in all testis: 2234.2 Mixed +NFRKB DKFZp547B2013, INO80G ENSG00000170322 Nuclear factor related to kappaB binding protein 11 129863636-129895590 Predicted intracellular proteins Evidence at protein level HPA007082, HPA007128 Approved Enhanced Nucleus Liver cancer:5.78e-4 (unfavourable) Expressed in all Expressed in all testis: 38.1 Expressed in all +FABP4 A-FABP, aP2 ENSG00000170323 Fatty acid binding protein 4 8 81478419-81483263 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002188, CAB024961 Enhanced Group enriched Tissue enriched 7 adipose tissue: 3652.0 breast: 559.1 Group enriched 277 ASC diff: 2538.9;RT4: 1531.5 +FRMPD2 MGC35285, PDZD5C, PDZK5C ENSG00000170324 FERM and PDZ domain containing 2 10 48153088-48274870 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enhanced cerebral cortex: 1.6;fallopian tube: 4.6 thyroid gland: 0.8 Cell line enhanced BEWO: 2.3;SCLC-21H: 1.2 +PRDM10 KIAA1231, MGC131802, PFM7 ENSG00000170325 PR/SET domain 10 11 129899706-130002835 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026997 Approved Approved Nucleoplasm
Nucleoli fibrillar center
Vesicles Expressed in all Mixed parathyroid gland: 7.6 Expressed in all +B3GNT2 B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT ENSG00000170340 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 2 62196113-62224731 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA005997 Approved Approved Vesicles Pancreatic cancer:1.62e-4 (unfavourable) Expressed in all Expressed in all lung: 51.0 Expressed in all +FOS AP-1, c-fos ENSG00000170345 Fos proto-oncogene, AP-1 transcription factor subunit 14 75278774-75282230 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018531 Approved Supported Nucleoplasm Prostate cancer:7.81e-4 (favourable) Expressed in all Expressed in all fallopian tube: 1853.4 Cell line enriched 5 hTCEpi: 324.8 +TMED10 p23, P24(DELTA), p24d1, p24delta1, TMP21 ENSG00000170348 Transmembrane p24 trafficking protein 10 14 75131470-75176631 Predicted membrane proteins Evidence at protein level CAB034442, CAB037251, HPA047139, HPA050539 Enhanced Supported Golgi apparatus Thyroid cancer:8.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 244.2 Expressed in all +SETMAR metnase ENSG00000170364 SET domain and mariner transposase fusion gene 3 4303304-4317567 Enzymes, Predicted intracellular proteins Evidence at protein level HPA057999 Supported Nucleoli Renal cancer:6.61e-6 (favourable), Liver cancer:2.85e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 16.0 Mixed +SMAD1 JV4-1, MADH1, MADR1 ENSG00000170365 SMAD family member 1 4 145481194-145558079 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005389 Approved Supported Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 67.4 Cell line enhanced HUVEC TERT2: 94.6 +CST5 ENSG00000170367 Cystatin D 20 23875935-23879750 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB024944, HPA061449 Enhanced Tissue enriched Tissue enriched 363 salivary gland: 756.2 lung,smooth muscle: 2.0 Not detected +CST2 ENSG00000170369 Cystatin SA 20 23823769-23826731 Predicted secreted proteins Evidence at protein level CAB024963, HPA043706, HPA044763 Enhanced Mixed Tissue enriched 281 salivary gland: 2052.3 gallbladder: 7.3 Cell line enriched 13 RT4: 53.8 +EMX2 ENSG00000170370 Empty spiracles homeobox 2 10 117542444-117549546 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003497, HPA065294 Enhanced Supported Approved Nucleus Renal cancer:2.28e-13 (favourable), Cervical cancer:2.80e-4 (favourable) Group enriched Group enriched 5 cervix, uterine: 59.5;endometrium: 114.9;epididymis: 115.2;fallopian tube: 73.0;kidney: 38.4;seminal vesicle: 65.3;smooth muscle: 59.8 cerebral cortex: 14.0 Cell line enhanced EFO-21: 22.1;fHDF/TERT166: 20.9;RPTEC TERT1: 19.9 +CST1 ENSG00000170373 Cystatin SN 20 23747553-23751268 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB026769, HPA043706, HPA044763 Enhanced Breast cancer:4.00e-4 (favourable) Mixed Tissue enriched 27 salivary gland: 9590.6 gallbladder: 352.0 Cell line enhanced CACO-2: 139.8;RT4: 891.2;TIME: 178.3 +SP7 osterix, OSX ENSG00000170374 Sp7 transcription factor 12 53326575-53345315 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029964, HPA063202 Enhanced Approved Not detected Tissue enhanced testis: 1.3 parathyroid gland,thyroid gland: 0.4 Not detected +TCAF2 FAM115C, FAM139A, FLJ40722 ENSG00000170379 TRPM8 channel associated factor 2 7 143620950-143730409 Predicted intracellular proteins Evidence at protein level HPA038756, HPA038758 Uncertain Supported Plasma membrane
Cell Junctions Renal cancer:4.17e-6 (unfavourable), Glioma:6.78e-5 (unfavourable) Mixed Mixed placenta: 8.1 Cell line enhanced HDLM-2: 11.0;TIME: 15.8;U-87 MG: 14.1 +SEMA3E coll-5, KIAA0331, M-SemaK, SEMAH ENSG00000170381 Semaphorin 3E 7 83363906-83649010 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029419, HPA063804 Uncertain Supported Approved Nucleoplasm
Vesicles Mixed Mixed prostate: 8.7 Cell line enhanced SK-BR-3: 29.4;U-2 OS: 21.3 +LRRN2 FIGLER7, GAC1, LRANK1, LRRN5 ENSG00000170382 Leucine rich repeat neuronal 2 1 204617170-204685733 Predicted membrane proteins Evidence at transcript level HPA029124 Uncertain Approved Endoplasmic reticulum Endometrial cancer:2.59e-7 (unfavourable) Group enriched Tissue enhanced cerebral cortex: 23.4;parathyroid gland: 21.2 fallopian tube: 11.5 Cell line enhanced HEL: 8.3;NTERA-2: 17.9;RPMI-8226: 20.1;T-47d: 9.4 +SLC30A1 ZNT1, ZRC1 ENSG00000170385 Solute carrier family 30 member 1 1 211571568-211578742 Predicted membrane proteins, Transporters Evidence at protein level HPA015275, HPA049000 Uncertain Supported Vesicles
Plasma membrane Expressed in all Mixed liver: 47.3 Expressed in all +DCLK2 DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428 ENSG00000170390 Doublecortin like kinase 2 4 150078274-150257457 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015770 Enhanced Pancreatic cancer:2.48e-4 (favourable), Ovarian cancer:3.25e-4 (favourable) Tissue enriched Tissue enriched 10 cerebral cortex: 82.6 heart muscle: 7.9 Cell line enhanced AF22: 23.3;BJ hTERT+: 20.2 +ZNF804A C2orf10 ENSG00000170396 Zinc finger protein 804A 2 184598366-184939492 Predicted intracellular proteins Evidence at protein level HPA029195 Uncertain Approved Endoplasmic reticulum Tissue enhanced Tissue enhanced cerebral cortex: 6.4 thyroid gland: 2.7 Cell line enhanced Daudi: 21.5;RH-30: 19.3;U-698: 15.3 +GPRC5C RAIG-3 ENSG00000170412 G protein-coupled receptor class C group 5 member C 17 74424851-74451653 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA029776 Enhanced Uncertain Nucleus
Microtubule organizing center
Cytosol Renal cancer:1.58e-5 (favourable) Expressed in all Mixed thyroid gland: 104.0 Cell line enhanced HMC-1: 144.5;RPTEC TERT1: 168.2;T-47d: 118.6 +TMEM182 FLJ30294 ENSG00000170417 Transmembrane protein 182 2 102736905-103019900 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045861 Uncertain Approved Nucleoplasm
Vesicles Expressed in all Group enriched 9 heart muscle: 56.8;skeletal muscle: 44.4 prostate: 5.8 Mixed +VSTM2A MGC33530, VSTM2 ENSG00000170419 V-set and transmembrane domain containing 2A 7 54542325-54571080 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA021404, HPA024134 Uncertain Renal cancer:5.34e-4 (favourable) Tissue enhanced Tissue enhanced adrenal gland: 12.7;cerebral cortex: 40.8;prostate: 15.5 stomach: 4.8 Cell line enhanced Karpas-707: 1.3;SCLC-21H: 6.9;SH-SY5Y: 4.3 +KRT8 CARD2, CK8, CYK8, K2C8, K8, KO ENSG00000170421 Keratin 8 12 52897187-52949954 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000131, CAB001696, HPA049866 Enhanced Supported Intermediate filaments Pancreatic cancer:1.51e-4 (unfavourable) Mixed Tissue enhanced small intestine: 1475.5 duodenum: 1118.4 Cell line enhanced A549: 5518.3;BEWO: 3855.6;CACO-2: 6334.4;CAPAN-2: 4191.3;MCF7: 7987.2;SK-BR-3: 3839.1;T-47d: 4059.8 +KRT78 K5B ENSG00000170423 Keratin 78 12 52837804-52849092 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039724 Enhanced Tissue enhanced Tissue enriched 8 esophagus: 1055.1 tonsil: 127.1 Group enriched 7 EFO-21: 5.3;RT4: 1.3;SK-BR-3: 3.0;U-87 MG: 3.0 +ADORA2B ENSG00000170425 Adenosine A2b receptor 17 15944917-15975746 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA073747 Uncertain Cytosol Mixed Mixed colon: 8.5 Cell line enhanced HMC-1: 142.9 +SDR9C7 RDHS, SDR-O ENSG00000170426 Short chain dehydrogenase/reductase family 9C member 7 12 56923154-56934405 Predicted intracellular proteins Evidence at protein level HPA039059 Approved Nucleoli
Cytosol Group enriched Tissue enhanced esophagus: 10.7;skin: 46.1 tonsil: 6.8 Not detected +MGMT ENSG00000170430 O-6-methylguanine-DNA methyltransferase 10 129467184-129768007 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB002786, HPA032135, HPA032136, HPA069497, CAB069881 Supported Enhanced Nucleoplasm Liver cancer:1.54e-4 (favourable), Cervical cancer:9.42e-4 (favourable) Expressed in all Expressed in all fallopian tube: 26.1 Mixed +METTL7B ALDI, MGC17301 ENSG00000170439 Methyltransferase like 7B 12 55681546-55684611 Predicted secreted proteins Evidence at protein level HPA038644 Enhanced Supported Vesicles
Microtubules Thyroid cancer:2.37e-4 (favourable), Head and neck cancer:2.85e-4 (unfavourable) Mixed Tissue enhanced epididymis: 137.1;liver: 122.2 small intestine: 52.1 Cell line enhanced CAPAN-2: 42.8;EFO-21: 33.6;LHCN-M2: 33.5;U-87 MG: 35.3 +KRT86 Hb6, KRTHB6, MNX ENSG00000170442 Keratin 86 12 52249300-52309163 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039798, HPA049778 Supported Approved Cytosol Mixed Tissue enhanced thyroid gland: 6.9 testis: 2.4 Cell line enhanced A-431: 21.8;A549: 23.3;MCF7: 39.4;RPMI-8226: 22.5 +HARS ENSG00000170445 Histidyl-tRNA synthetase 5 140673173-140692024 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036539 Approved Enhanced Cytosol Liver cancer:1.96e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 71.1 Expressed in all +NFXL1 HOZFP ENSG00000170448 Nuclear transcription factor, X-box binding like 1 4 47847233-47914667 Predicted membrane proteins, Transcription factors Evidence at protein level HPA059132 Approved Approved Nucleoplasm Liver cancer:9.28e-4 (unfavourable) Expressed in all Mixed testis: 24.9 Expressed in all +KRT75 K6HF ENSG00000170454 Keratin 75 12 52424070-52434525 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019367, HPA076201 Supported Approved Plasma membrane
Cytosol Tissue enhanced Not detected breast: 0.9 Group enriched 8 PC-3: 33.1;U-2 OS: 48.9 +DENND5B MGC24039 ENSG00000170456 DENN domain containing 5B 12 31382223-31591097 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038865 Approved Approved Nucleoli
Microtubules Expressed in all Mixed testis: 29.6 Mixed +CD14 ENSG00000170458 CD14 molecule 5 140631728-140633701 Cancer-related genes, CD markers, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001887, HPA002127, CAB033631, CAB072865, CAB072866 Enhanced Supported Vesicles Renal cancer:6.80e-5 (unfavourable) Expressed in all Expressed in all appendix: 267.3 Cell line enhanced A549: 8.6;CACO-2: 12.0;SiHa: 18.3 +DNAJC18 MGC29463 ENSG00000170464 DnaJ heat shock protein family (Hsp40) member C18 5 139408588-139444491 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036538, HPA060154 Approved Supported Cell Junctions Pancreatic cancer:5.89e-4 (favourable) Mixed Group enriched 5 cerebral cortex: 30.2;testis: 115.6 ovary: 13.8 Mixed +KRT6C KRT6E ENSG00000170465 Keratin 6C 12 52468516-52473785 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045697, HPA061168 Supported Supported Intermediate filaments Lung cancer:1.23e-5 (unfavourable) Tissue enhanced Tissue enriched 50 esophagus: 525.3 cervix, uterine: 10.6 Cell line enriched 6 RPMI-8226: 66.4 +RIOX1 C14orf169, FLJ21802, JMJD9, MAPJD, NO66 ENSG00000170468 Ribosomal oxygenase 1 14 73490964-73493392 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003730 Supported Nucleoli Expressed in all Expressed in all testis: 17.7 Mixed +SPATA24 CCDC161, T6441 ENSG00000170469 Spermatogenesis associated 24 5 139396563-139404088 Predicted intracellular proteins Evidence at protein level HPA044000 Enhanced Supported Nucleus
Cytosol Liver cancer:2.75e-4 (unfavourable) Expressed in all Tissue enriched 7 testis: 177.4 epididymis: 25.6 Expressed in all +RALGAPB DKFZp781M2411, KIAA1219, RalGAPbeta ENSG00000170471 Ral GTPase activating protein non-catalytic beta subunit 20 38472816-38578861 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051454 Approved Approved Nuclear speckles Renal cancer:7.25e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 46.2 Expressed in all +PYM1 PYM, WIBG ENSG00000170473 PYM homolog 1, exon junction complex associated factor 12 55901413-55932618 Predicted intracellular proteins Evidence at protein level CAB012803, HPA039717, HPA046200 Supported Supported Nucleus
Nucleoli
Cell Junctions
Cytosol Urothelial cancer:1.34e-4 (favourable), Liver cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all epididymis: 50.6 Expressed in all +MZB1 HSPC190, MEDA-7, MGC29506, PACAP, pERp1 ENSG00000170476 Marginal zone B and B1 cell specific protein 5 139387480-139390081 Predicted secreted proteins Evidence at protein level HPA043745, HPA052694 Enhanced Renal cancer:1.15e-8 (unfavourable), Head and neck cancer:4.60e-5 (favourable), Endometrial cancer:7.27e-4 (favourable) Mixed Mixed lymph node: 160.4 Cell line enhanced Karpas-707: 505.9;RPMI-8226: 1791.3 +KRT4 CK4, CYK4, K4 ENSG00000170477 Keratin 4 12 52806549-52814551 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002154, HPA034881 Supported Enhanced Intermediate filaments Ovarian cancer:3.26e-4 (unfavourable), Urothelial cancer:6.26e-4 (unfavourable) Group enriched Tissue enriched 25 esophagus: 14861.9 tonsil: 599.4 Group enriched 28 HaCaT: 385.2;SK-BR-3: 130.9 +SLC23A1 SLC23A2, SVCT1, YSPL3 ENSG00000170482 Solute carrier family 23 member 1 5 139367196-139384553 Predicted membrane proteins, Transporters Evidence at protein level HPA047612 Enhanced Group enriched Group enriched 5 duodenum: 26.7;fallopian tube: 86.2;kidney: 41.9;small intestine: 72.0 liver: 10.7 Cell line enhanced CACO-2: 7.7;HDLM-2: 7.6;Hep G2: 9.2;Karpas-707: 7.8;RPMI-8226: 7.6;U-266/70: 12.7 +KRT74 K6IRS4, KRT5C, KRT6IRS4 ENSG00000170484 Keratin 74 12 52565782-52573825 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA048596 Supported Not detected Tissue enriched 6 epididymis: 6.9 breast: 1.1 Not detected +NPAS2 bHLHe9, MOP4, PASD4 ENSG00000170485 Neuronal PAS domain protein 2 2 100820152-100996829 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019674 Uncertain Supported Approved Nucleoplasm Renal cancer:3.55e-7 (unfavourable), Liver cancer:2.07e-4 (unfavourable) Expressed in all Mixed esophagus: 27.5 Cell line enhanced PC-3: 102.3 +KRT72 K6irs, K6IRS2, KRT6, KRT6IRS2 ENSG00000170486 Keratin 72 12 52585589-52601538 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065523 Supported Not detected Tissue enriched 5 testis: 26.8 skin: 5.2 Not detected +KISS1 ENSG00000170498 KiSS-1 metastasis-suppressor 1 204190341-204196486 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level CAB017775, HPA035542 Enhanced Approved Vesicles Urothelial cancer:6.29e-6 (favourable) Tissue enhanced Tissue enriched 87 placenta: 328.1 stomach: 3.7 Group enriched 21 BJ: 123.9;U-2 OS: 60.5 +LONRF2 FLJ45273, RNF192 ENSG00000170500 LON peptidase N-terminal domain and ring finger 2 2 100273291-100322733 Predicted intracellular proteins Evidence at protein level HPA057366 Approved Supported Nucleus Pancreatic cancer:6.42e-5 (favourable) Tissue enhanced Tissue enhanced epididymis: 55.6 endometrium: 45.2 Cell line enhanced HAP1: 6.0;HEK 293: 5.7;SCLC-21H: 14.7 +NUDT9 MGC3037 ENSG00000170502 Nudix hydrolase 9 4 87422582-87459454 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036917, HPA044866 Approved Renal cancer:8.00e-11 (favourable), Endometrial cancer:7.43e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 85.9 Expressed in all +HSD17B13 SCDR9, SDR16C3 ENSG00000170509 Hydroxysteroid 17-beta dehydrogenase 13 4 87303789-87322906 Predicted intracellular proteins Evidence at protein level HPA029125 Uncertain Approved Golgi apparatus
Vesicles Liver cancer:2.94e-4 (favourable), Lung cancer:7.80e-4 (favourable) Tissue enriched Tissue enriched 29 liver: 294.1 adipose tissue: 10.2 Not detected +PA2G4 ENSG00000170515 Proliferation-associated 2G4 12 56104319-56113907 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011711, CAB012428, HPA016484 Supported Approved Cytosol Renal cancer:4.59e-7 (unfavourable), Liver cancer:6.31e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 138.1 Expressed in all +COX7B2 ENSG00000170516 Cytochrome c oxidase subunit 7B2 4 46734827-46909235 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Tissue enhanced Tissue enriched 100 testis: 148.8 placenta: 1.4 Cell line enriched 12 Karpas-707: 25.2 +ELOVL6 FLJ23378, LCE, MGC5487 ENSG00000170522 ELOVL fatty acid elongase 6 4 110045846-110199199 Enzymes, Predicted membrane proteins Evidence at protein level HPA042355 Uncertain Colorectal cancer:6.74e-4 (favourable) Expressed in all Mixed liver: 27.9 Mixed +KRT83 Hb-3, KRTHB3 ENSG00000170523 Keratin 83 12 52314301-52321398 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049778 Supported Tissue enhanced Tissue enhanced thyroid gland: 1.7 breast,testis: 0.3 Cell line enhanced A549: 2.9;MCF7: 2.0;RPMI-8226: 9.3 +PFKFB3 ENSG00000170525 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 10 6144934-6254644 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008266, CAB020795, HPA043889 Uncertain Enhanced Nucleoplasm Renal cancer:1.87e-7 (unfavourable) Expressed in all Expressed in all adipose tissue: 345.8 Expressed in all +TMC7 FLJ21240 ENSG00000170537 Transmembrane channel like 7 16 18983934-19063942 Predicted membrane proteins Evidence at protein level HPA029465 Uncertain Approved Vesicles Lung cancer:3.20e-4 (unfavourable), Pancreatic cancer:7.64e-4 (unfavourable), Urothelial cancer:9.20e-4 (favourable) Mixed Tissue enhanced testis: 17.8 cerebral cortex: 10.7 Mixed +ARL6IP1 AIP1, ARL6IP, ARMER, KIAA0069, SPG61 ENSG00000170540 ADP ribosylation factor like GTPase 6 interacting protein 1 16 18791667-18801678 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045307 Uncertain Approved Endoplasmic reticulum Expressed in all Expressed in all cerebral cortex: 386.9 Expressed in all +SERPINB9 CAP3, PI9 ENSG00000170542 Serpin family B member 9 6 2887266-2903280 Predicted intracellular proteins Evidence at protein level HPA030067 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.66e-6 (unfavourable) Expressed in all Tissue enhanced placenta: 74.8 appendix: 48.4 Cell line enhanced BEWO: 219.1;U-698: 69.6 +SMAGP hSMAGP, MGC149453, MGC149454 ENSG00000170545 Small cell adhesion glycoprotein 12 51244558-51270890 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039711 Enhanced Supported Nucleoplasm
Plasma membrane Renal cancer:2.24e-4 (favourable), Pancreatic cancer:4.38e-4 (unfavourable), Glioma:7.05e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 145.7 esophagus: 83.3 Cell line enhanced BEWO: 126.2 +IRX1 IRX-5 ENSG00000170549 Iroquois homeobox 1 5 3596054-3601403 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043160 Uncertain Approved Nucleoplasm
Golgi apparatus Group enriched Tissue enhanced breast: 7.7;kidney: 5.3;salivary gland: 5.7 lung: 3.6 Cell line enhanced AF22: 9.8;REH: 38.0;U-251 MG: 13.8 +CDH2 CD325, CDHN, NCAD ENSG00000170558 Cadherin 2 18 27950966-28177446 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000141, CAB018580, HPA058574, CAB078686 Enhanced Supported Plasma membrane
Cell Junctions Expressed in all Tissue enhanced heart muscle: 123.5;parathyroid gland: 126.2 adrenal gland: 87.3 Cell line enhanced AF22: 306.2;fHDF/TERT166: 367.9 +IRX2 ENSG00000170561 Iroquois homeobox 2 5 2745845-2751662 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050895, HPA054669 Approved Approved Nucleus
Nucleoli Pancreatic cancer:8.84e-4 (favourable) Mixed Tissue enhanced breast: 29.6;lung: 28.0 skin: 19.5 Cell line enhanced AF22: 100.0;BEWO: 58.5;hTCEpi: 47.9 +EMB MGC71745 ENSG00000170571 Embigin 5 50396192-50443248 Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:2.76e-5 (unfavourable) Expressed in all Mixed bone marrow: 94.7 Cell line enhanced THP-1: 182.2 +SIX2 ENSG00000170577 SIX homeobox 2 2 45005161-45009430 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056958 Supported Nucleoplasm
Nuclear membrane Mixed Group enriched 5 cervix, uterine: 18.7;parathyroid gland: 8.6;prostate: 6.3;salivary gland: 9.4;skeletal muscle: 6.7 adipose tissue: 1.9 Cell line enhanced ASC TERT1: 34.1;LHCN-M2: 39.0;RH-30: 30.9;SCLC-21H: 63.8;U-2197: 32.8;U-698: 29.5 +DLGAP1 DAP-1, GKAP, SAPAP1 ENSG00000170579 DLG associated protein 1 18 3496032-4455335 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 6 cerebral cortex: 91.2 seminal vesicle: 14.6 Cell line enhanced Daudi: 7.6;HAP1: 3.8;U-2197: 3.0 +STAT2 STAT113 ENSG00000170581 Signal transducer and activator of transcription 2 12 56341597-56360155 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003858, HPA018888 Approved Supported Plasma membrane
Cytosol Renal cancer:4.78e-13 (unfavourable), Endometrial cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all spleen: 47.9 Expressed in all +NUDCD2 DKFZp686E10109, NudCL2 ENSG00000170584 NudC domain containing 2 5 163446526-163460140 Predicted intracellular proteins Evidence at protein level HPA037384, HPA037385 Uncertain Colorectal cancer:2.80e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 24.6 Expressed in all +IRF2BP1 DKFZP434M154, IRF-2BP1 ENSG00000170604 Interferon regulatory factor 2 binding protein 1 19 45883607-45886170 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042164, HPA049480 Approved Supported Nucleoplasm Renal cancer:3.85e-5 (favourable), Pancreatic cancer:2.32e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 13.2 Expressed in all +OR9K2 ENSG00000170605 Olfactory receptor family 9 subfamily K member 2 12 55129681-55130802 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA015808 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +HSPA4 HS24/P52, HSPH2 ENSG00000170606 Heat shock protein family A (Hsp70) member 4 5 133051962-133106449 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA010023, CAB025529 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:4.13e-4 (unfavourable) Expressed in all Expressed in all testis: 116.7 Expressed in all +FOXA3 HNF3G ENSG00000170608 Forkhead box A3 19 45863989-45873797 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB015154, HPA054034 Uncertain Approved Nucleoplasm Mixed Group enriched 5 colon: 16.7;duodenum: 10.3;liver: 32.5;pancreas: 9.8;rectum: 17.9;small intestine: 13.9;stomach: 33.8 gallbladder: 3.6 Cell line enhanced CACO-2: 8.4;HDLM-2: 11.2;Hep G2: 18.9;K-562: 20.1;NTERA-2: 10.8 +FAM71B MGC26988 ENSG00000170613 Family with sequence similarity 71 member B 5 157161846-157166264 Predicted intracellular proteins Evidence at protein level HPA039478, HPA040771 Enhanced Not detected Tissue enriched 372 testis: 37.2 all non-specific tissues: 0.0 Not detected +SLC26A5 DFNB61, PRES ENSG00000170615 Solute carrier family 26 member 5 7 103352730-103446177 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at transcript level Mixed Not detected breast,parathyroid gland: 0.9 Not detected +COMMD5 FLJ13008, HCaRG, HT002 ENSG00000170619 COMM domain containing 5 8 144841042-144853736 Predicted intracellular proteins Evidence at protein level HPA046905 Supported Nucleoplasm
Cytosol Expressed in all Expressed in all lymph node: 18.2 Expressed in all +SGCD CMD1L, DAGD, LGMD2F ENSG00000170624 Sarcoglycan delta 5 155870344-156767788 Disease related genes, Predicted membrane proteins Evidence at protein level HPA026969 Uncertain Tissue enhanced Mixed thyroid gland: 37.4 Cell line enhanced BJ: 19.4;fHDF/TERT166: 28.5;RH-30: 26.8;SK-MEL-30: 28.7;U-138 MG: 34.9 +GTSF1 FAM112B, FLJ32942 ENSG00000170627 Gametocyte specific factor 1 12 54455950-54473602 Predicted intracellular proteins Evidence at protein level HPA038876, HPA038877 Approved Approved Nucleoplasm Tissue enriched Tissue enriched 16 testis: 333.8 placenta: 20.9 Cell line enhanced HL-60: 233.8;K-562: 259.6;NB-4: 280.4;THP-1: 272.7;U-266/84: 235.1 +ZNF16 KOX9 ENSG00000170631 Zinc finger protein 16 8 144930358-144950888 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035782, HPA061835 Uncertain Supported Nucleus
Nucleoli Head and neck cancer:2.39e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 16.1 Expressed in all +ARMC10 MGC3195, SVH ENSG00000170632 Armadillo repeat containing 10 7 103074881-103099764 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011036, HPA011057 Enhanced Supported Mitochondria Pancreatic cancer:2.49e-6 (unfavourable), Glioma:6.98e-6 (unfavourable), Liver cancer:3.58e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.6 Expressed in all +RNF34 FLJ21786, RIF, RIFF ENSG00000170633 Ring finger protein 34 12 121400041-121430623 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA074151 Supported Nucleoplasm
Nuclear bodies Liver cancer:6.72e-8 (unfavourable), Urothelial cancer:3.02e-4 (favourable), Renal cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all testis: 45.8 Expressed in all +ACYP2 ENSG00000170634 Acylphosphatase 2 2 53970838-54305300 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035301 Uncertain Approved Nucleoplasm Expressed in all Expressed in all skeletal muscle: 73.7 Expressed in all +TRABD PP2447 ENSG00000170638 TraB domain containing 22 50185915-50199598 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA000822 Approved Approved Nucleus
Mitochondria Endometrial cancer:1.19e-5 (favourable), Renal cancer:1.85e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 38.5 Expressed in all +TMEM133 AD031 ENSG00000170647 Transmembrane protein 133 11 100991989-100993941 Predicted membrane proteins Evidence at protein level HPA060528, HPA065742 Uncertain Approved Endoplasmic reticulum
Golgi apparatus Pancreatic cancer:1.76e-4 (unfavourable) Expressed in all Mixed placenta: 18.3 Cell line enhanced CAPAN-2: 12.4 +ATF7 ATFA ENSG00000170653 Activating transcription factor 7 12 53507856-53626410 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA003384 Approved Approved Nucleus
Cytosol Stomach cancer:2.10e-4 (unfavourable) Expressed in all Expressed in all endometrium: 40.3 Expressed in all +RASA4B ENSG00000170667 RAS p21 protein activator 4B 7 102482445-102517781 Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level HPA043010 Uncertain Uncertain Vesicles
Cell Junctions Not detected Tissue enhanced skeletal muscle: 39.7 cerebral cortex: 15.7 Cell line enhanced SH-SY5Y: 14.3;U-138 MG: 18.0;U-2 OS: 16.6 +SOCS6 CIS4, Cish4, HSPC060, SOCS4, SSI4, STAI4, STATI4 ENSG00000170677 Suppressor of cytokine signaling 6 18 70288901-70330200 Predicted intracellular proteins Evidence at protein level CAB010189 Uncertain Approved Nuclear speckles
Cytosol Renal cancer:1.02e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.0 Mixed +MURC cavin-4, CAVIN4 ENSG00000170681 Muscle related coiled-coil protein 9 100578079-100587906 Predicted intracellular proteins Evidence at protein level HPA020973, HPA020987, HPA021021 Enhanced Supported Nucleoplasm
Golgi apparatus
Plasma membrane Tissue enhanced Group enriched 9 heart muscle: 34.8;skeletal muscle: 103.8 prostate: 7.4 Cell line enhanced NTERA-2: 9.6;SCLC-21H: 17.1 +OR10A3 HSHTPCRX12, HTPCRX12 ENSG00000170683 Olfactory receptor family 10 subfamily A member 3 11 7938534-7939594 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF296 ZNF342 ENSG00000170684 Zinc finger protein 296 19 45071500-45076588 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046940, HPA049576 Uncertain Approved Nucleoplasm
Centrosome Head and neck cancer:5.24e-4 (favourable) Expressed in all Mixed spleen: 3.7 Cell line enhanced Daudi: 16.2;U-698: 18.2 +HOXB9 HOX2, HOX2E ENSG00000170689 Homeobox B9 17 48621159-48626356 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031463 Approved Nucleoplasm
Mitochondria Head and neck cancer:6.64e-5 (unfavourable), Endometrial cancer:4.47e-4 (unfavourable) Tissue enhanced Tissue enhanced epididymis: 107.2 colon: 26.1 Cell line enhanced HDLM-2: 315.3;HEK 293: 116.2;HMC-1: 112.5;K-562: 130.4 +TTLL6 FLJ35808 ENSG00000170703 Tubulin tyrosine ligase like 6 17 48762235-48817214 Predicted intracellular proteins Evidence at protein level HPA052397 Enhanced Approved Vesicles
Microtubules Mixed Tissue enhanced testis: 26.0 fallopian tube: 5.8 Cell line enriched 5 HDLM-2: 4.1 +POLH RAD30A, XP-V ENSG00000170734 DNA polymerase eta 6 43576150-43615660 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006721, HPA026762 Approved Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 20.8 Expressed in all +SYT9 ENSG00000170743 Synaptotagmin 9 11 7238778-7469042 Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced cerebral cortex: 6.1;seminal vesicle: 5.1 adrenal gland: 2.7 Cell line enhanced HEK 293: 9.6;RT4: 14.7;SH-SY5Y: 14.3;TIME: 16.8 +KCNS3 Kv9.3 ENSG00000170745 Potassium voltage-gated channel modifier subfamily S member 3 2 17877847-18361616 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA014864 Approved Supported Golgi apparatus
Plasma membrane
Cytosol Renal cancer:1.53e-4 (unfavourable) Expressed in all Tissue enhanced lung: 35.5 skeletal muscle: 29.6 Cell line enhanced RH-30: 66.9;RT4: 38.5 +RBMXL2 HNRNPG-T, HNRPGT ENSG00000170748 RNA binding motif protein, X-linked like 2 11 7089027-7090900 Predicted intracellular proteins Evidence at protein level HPA038912, HPA051842 Enhanced Tissue enriched Tissue enriched 499 testis: 49.8 all non-specific tissues: 0.0 Not detected +KIF5B KNS, KNS1 ENSG00000170759 Kinesin family member 5B 10 32009010-32056431 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009846, HPA037589, HPA037590 Approved Enhanced Microtubule organizing center
Cytosol Expressed in all Expressed in all parathyroid gland: 187.6 Expressed in all +GPR37 EDNRBL, hET(B)R-LP, PAELR ENSG00000170775 G protein-coupled receptor 37 7 124745997-124765627 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA042903, HPA068009 Approved Approved Nuclear membrane
Cytosol Lung cancer:6.00e-5 (unfavourable), Ovarian cancer:7.26e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 78.7;testis: 27.6 placenta: 12.8 Cell line enhanced AF22: 12.8;fHDF/TERT166: 24.0;TIME: 17.5 +AKAP13 AKAP-Lbc, ARHGEF13, BRX, c-lbc, HA-3, Ht31, LBC, PROTO-LB ENSG00000170776 A-kinase anchoring protein 13 15 85380571-85749358 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019773 Approved Supported Cytosol Expressed in all Expressed in all endometrium: 74.5 Expressed in all +TPD52L3 NYD-SP25 ENSG00000170777 Tumor protein D52 like 3 9 6328375-6331900 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 2754 testis: 275.3 all non-specific tissues: 0.0 Cell line enriched 12 BEWO: 1.2 +CDCA4 FLJ20764, Hepp ENSG00000170779 Cell division cycle associated 4 14 105009573-105021148 Predicted intracellular proteins Evidence at protein level HPA059416, HPA064971 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.47e-6 (unfavourable), Liver cancer:4.19e-4 (unfavourable), Pancreatic cancer:6.67e-4 (unfavourable), Lung cancer:7.94e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 32.9 testis: 13.8 Expressed in all +OR10A4 OR10A4P ENSG00000170782 Olfactory receptor family 10 subfamily A member 4 11 6876625-6877619 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +SDR16C5 EPHD-2, RDH-E2, RDHE2 ENSG00000170786 Short chain dehydrogenase/reductase family 16C member 5 8 56300010-56320776 Enzymes, Predicted membrane proteins Evidence at protein level HPA025224 Enhanced Head and neck cancer:7.88e-4 (favourable) Mixed Group enriched 6 breast: 15.2;esophagus: 36.3;lung: 40.3;skin: 72.9;small intestine: 21.7;stomach: 21.0;tonsil: 25.3 cervix, uterine: 5.6 Cell line enhanced CAPAN-2: 22.6;HaCaT: 11.3;hTCEpi: 15.1;T-47d: 9.2 +DYDC1 bA36D19.5, DPY30D1 ENSG00000170788 DPY30 domain containing 1 10 80336105-80356755 Predicted intracellular proteins Evidence at protein level HPA037790, HPA037791 Uncertain Tissue enhanced Tissue enriched 21 testis: 200.6 fallopian tube: 9.5 Not detected +OR10A2 OR10A2P, OST363 ENSG00000170790 Olfactory receptor family 10 subfamily A member 2 11 6869693-6870745 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +CHCHD7 COX23, MGC2217 ENSG00000170791 Coiled-coil-helix-coiled-coil-helix domain containing 7 8 56211686-56218798 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050783 Approved Approved Cell Junctions
Aggresome Endometrial cancer:1.39e-6 (unfavourable), Renal cancer:9.47e-5 (favourable) Expressed in all Expressed in all ovary: 61.6 Expressed in all +HTRA3 Prsp, Tasp ENSG00000170801 HtrA serine peptidase 3 4 8269765-8307111 Enzymes, Predicted secreted proteins Evidence at protein level HPA021187, HPA063810 Approved Approved Vesicles Renal cancer:1.61e-9 (unfavourable), Thyroid cancer:1.29e-4 (unfavourable) Expressed in all Mixed ovary: 60.9 Cell line enriched 6 U-2197: 168.9 +FOXN2 HTLF ENSG00000170802 Forkhead box N2 2 48314637-48379294 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003485 Supported Supported Nucleus
Vesicles Renal cancer:2.81e-5 (unfavourable), Glioma:5.14e-4 (favourable) Expressed in all Expressed in all bone marrow: 36.4 Expressed in all +LMOD2 ENSG00000170807 Leiomodin 2 7 123655807-123664290 Predicted intracellular proteins Evidence at protein level HPA051039 Enhanced Group enriched Group enriched 19 heart muscle: 506.5;skeletal muscle: 316.7 esophagus: 21.9 Cell line enriched 8 HSkMC: 1.0 +BFSP2 CP47, CP49, LIFL-L, phakinin ENSG00000170819 Beaded filament structural protein 2 3 133399995-133475222 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038464, HPA062959 Enhanced Uncertain Plasma membrane
Cytosol Tissue enriched Not detected lymph node: 0.4 Group enriched 7 Daudi: 1.5;U-698: 1.7 +FSHR FSHRO, LGR1, ODG1 ENSG00000170820 Follicle stimulating hormone receptor 2 48962157-49154537 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Not detected Group enriched 9 ovary: 2.5;testis: 4.3 gallbladder: 0.3 Not detected +USP32 NY-REN-60, USP10 ENSG00000170832 Ubiquitin specific peptidase 32 17 60179094-60422470 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044365 Approved Approved Golgi apparatus
Cytosol Endometrial cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all testis: 155.0 Expressed in all +CEL BSSL, MODY8 ENSG00000170835 Carboxyl ester lipase 9 133061978-133071861 Predicted secreted proteins Evidence at protein level HPA008023, HPA052701 Enhanced Breast cancer:4.14e-4 (unfavourable) Tissue enriched Tissue enriched 95 pancreas: 23233.0 epididymis: 244.0 Mixed +PPM1D PP2C-DELTA, Wip1 ENSG00000170836 Protein phosphatase, Mg2+/Mn2+ dependent 1D 17 60600183-60666280 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022277 Uncertain Approved Endoplasmic reticulum Colorectal cancer:3.52e-4 (favourable), Liver cancer:4.27e-4 (unfavourable) Expressed in all Mixed testis: 9.6 Expressed in all +GPR27 SREB1 ENSG00000170837 G protein-coupled receptor 27 3 71754050-71756496 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA029395 Approved Approved Nucleoplasm
Plasma membrane
Actin filaments
Cytosol Ovarian cancer:1.21e-6 (favourable), Breast cancer:5.63e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 46.5 cerebral cortex: 24.9 Cell line enhanced EFO-21: 17.2;HL-60: 14.7;NTERA-2: 30.5;SH-SY5Y: 12.3 +PSG6 ENSG00000170848 Pregnancy specific beta-1-glycoprotein 6 19 42902079-42919563 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046327 Approved Not detected Tissue enriched 75 placenta: 70.2 bone marrow: 0.9 Cell line enriched 18 U-2197: 134.3 +KBTBD2 BKLHD1, DKFZP566C134 ENSG00000170852 Kelch repeat and BTB domain containing 2 7 32868172-32894131 Predicted intracellular proteins Evidence at protein level HPA021133 Uncertain Approved Nucleus
Nucleoli fibrillar center Cervical cancer:1.89e-4 (unfavourable), Liver cancer:5.69e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 38.6 Expressed in all +RIOX2 FLJ14393, JMJD10, mdig, MINA, MINA53, NO52 ENSG00000170854 Ribosomal oxygenase 2 3 97941818-97972457 Predicted intracellular proteins Evidence at protein level HPA007603, HPA008080, CAB013458 Supported Enhanced Nucleus
Nucleoli Breast cancer:4.41e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 100.7 Mixed +TRIAP1 HSPC132, MDM35, P53CSV, WF-1 ENSG00000170855 TP53 regulated inhibitor of apoptosis 1 12 120443961-120446412 Predicted intracellular proteins, Transporters Evidence at protein level HPA053640 Approved Approved Nucleoplasm
Mitochondria Melanoma:2.22e-4 (unfavourable), Renal cancer:8.77e-4 (unfavourable) Expressed in all Expressed in all placenta: 40.3 Expressed in all +LSM3 SMX4, USS2, YLR438C ENSG00000170860 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated 3 14178358-14201119 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044966 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all kidney: 21.1 Expressed in all +KIAA0232 ENSG00000170871 KIAA0232 4 6781375-6884170 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036891, HPA036892, HPA061498 Approved Approved Cytosol Renal cancer:3.91e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 38.8 Expressed in all +MTSS1 KIAA0429, MIM, MIMA, MIMB ENSG00000170873 MTSS1, I-BAR domain containing 8 124550790-124728429 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA075540 Approved Renal cancer:2.11e-7 (favourable) Expressed in all Expressed in all placenta: 51.6 Cell line enhanced HDLM-2: 92.3;HEL: 304.1 +TMEM43 ARVD5, DKFZp586G1919, LUMA, MGC3222 ENSG00000170876 Transmembrane protein 43 3 14124940-14143679 Disease related genes, Predicted membrane proteins Evidence at protein level HPA019198 Approved Pancreatic cancer:4.38e-4 (unfavourable) Expressed in all Expressed in all skin: 124.4 Expressed in all +RNF139 HRCA1, RCA1, TRC8 ENSG00000170881 Ring finger protein 139 8 124474738-124487914 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA001202 Approved Pancreatic cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all testis: 114.8 Expressed in all +RPS9 S9 ENSG00000170889 Ribosomal protein S9 19 54200742-54249003 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA048746 Approved Renal cancer:1.63e-4 (unfavourable), Breast cancer:9.23e-4 (favourable) Expressed in all Expressed in all ovary: 112.4 Expressed in all +PLA2G1B PLA2, PLA2A, PPLA2 ENSG00000170890 Phospholipase A2 group IB 12 120322111-120327789 Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB022329, HPA047822, HPA060803 Enhanced Enhanced Cytosol Tissue enriched Tissue enriched 246 pancreas: 23843.3 ovary: 96.9 Cell line enhanced Hep G2: 1.7;U-2 OS: 1.8 +CYTL1 C17, C4orf4 ENSG00000170891 Cytokine like 1 4 5014586-5019472 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA067201 Supported Nuclear membrane
Endoplasmic reticulum Stomach cancer:3.00e-5 (unfavourable), Urothelial cancer:1.25e-4 (unfavourable), Renal cancer:7.43e-4 (unfavourable) Tissue enhanced Tissue enhanced placenta: 64.9 seminal vesicle: 19.1 Cell line enhanced HEL: 171.3;HUVEC TERT2: 124.6;NB-4: 237.3;WM-115: 86.9 +TSEN34 LENG5, SEN34, SEN34L ENSG00000170892 TRNA splicing endonuclease subunit 34 19 54189938-54194536 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041111, HPA048208 Approved Supported Nucleus Liver cancer:1.44e-7 (unfavourable) Expressed in all Mixed fallopian tube: 37.2 Mixed +TRH ENSG00000170893 Thyrotropin releasing hormone 3 129974305-129977938 Predicted secreted proteins Evidence at protein level HPA035596 Enhanced Tissue enhanced Group enriched 9 cervix, uterine: 32.1;endometrium: 27.4 fallopian tube: 3.4 Not detected +GSTA4 ENSG00000170899 Glutathione S-transferase alpha 4 6 52977948-52995378 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048934 Approved Expressed in all Expressed in all adrenal gland: 390.0 Cell line enhanced AF22: 92.3 +MSANTD4 KIAA1826 ENSG00000170903 Myb/SANT DNA binding domain containing 4 with coiled-coils 11 105995623-106022403 Predicted intracellular proteins Evidence at protein level HPA014411 Approved Approved Nucleus Renal cancer:1.26e-5 (favourable), Breast cancer:4.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 27.4 Mixed +NDUFA3 B9 ENSG00000170906 NADH:ubiquinone oxidoreductase subunit A3 19 54102728-54109257 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046976 Supported Urothelial cancer:4.80e-4 (favourable), Pancreatic cancer:9.65e-4 (favourable) Expressed in all Expressed in all skin: 16.0 Expressed in all +OSCAR ENSG00000170909 Osteoclast associated, immunoglobulin-like receptor 19 54094668-54102692 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Renal cancer:2.71e-5 (unfavourable) Expressed in all Tissue enhanced bone marrow: 9.0;lung: 14.1 appendix: 3.3 Cell line enhanced EFO-21: 13.1;HHSteC: 7.9;U-937: 14.0 +PAQR8 C6orf33, LMPB1, MPRB ENSG00000170915 Progestin and adipoQ receptor family member 8 6 52361421-52407777 Predicted membrane proteins Evidence at protein level HPA064625 Supported Golgi apparatus
Plasma membrane Breast cancer:4.61e-4 (favourable), Urothelial cancer:6.40e-4 (favourable) Expressed in all Mixed cerebral cortex: 64.9 Cell line enhanced Hep G2: 28.4 +NUDT6 FGF-AS, FGF2AS, gfg, gfg-1 ENSG00000170917 Nudix hydrolase 6 4 122888697-122922968 Predicted intracellular proteins Evidence at protein level HPA039202, HPA066115 Uncertain Approved Microtubules Mixed Mixed kidney: 20.0 Expressed in all +OR7G3 OST085 ENSG00000170920 Olfactory receptor family 7 subfamily G member 3 19 9126012-9126950 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +TANC2 DKFZP564D166, FLJ10215, FLJ11824, KIAA1148, KIAA1636, rols, ROLSA ENSG00000170921 Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 17 63009556-63427699 Predicted intracellular proteins Evidence at protein level HPA023274 Uncertain Approved Cytosol Mixed Tissue enhanced parathyroid gland: 78.0 testis: 34.9 Mixed +OR7G2 OST260 ENSG00000170923 Olfactory receptor family 7 subfamily G member 2 19 9102269-9103306 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +TEX13B TGC3B, TSGA5 ENSG00000170925 Testis expressed 13B X 107980864-107982370 Predicted intracellular proteins Evidence at protein level HPA011283 Uncertain Not detected Not detected testis: 0.8 Not detected +PKHD1 ARPKD, FCYT, TIGM1 ENSG00000170927 Polycystic kidney and hepatic disease 1 (autosomal recessive) 6 51615300-52087625 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA031227 Approved Renal cancer:9.74e-8 (favourable) Group enriched Group enriched 5 epididymis: 5.7;kidney: 15.3 pancreas: 1.9 Cell line enriched 7 RPTEC TERT1: 8.1 +OR1M1 OR19-6 ENSG00000170929 Olfactory receptor family 1 subfamily M member 1 19 9093179-9094213 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected fallopian tube: 0.1 Not detected +NCBP2L ENSG00000170935 Nuclear cap binding protein subunit 2-like X 107774899-107795829 Predicted intracellular proteins Evidence at transcript level HPA010664 Uncertain Not detected Tissue enhanced adrenal gland: 1.4;testis: 3.9 fallopian tube: 1.2 Not detected +DNAJC24 DPH4, JJJ3, ZCSL3 ENSG00000170946 DnaJ heat shock protein family (Hsp40) member C24 11 31369840-31431849 Predicted intracellular proteins Evidence at protein level HPA020025, HPA025237 Approved Approved Cytosol Expressed in all Expressed in all cerebral cortex,thyroid gland: 11.3 Expressed in all +MBD3L1 MBD3L ENSG00000170948 Methyl-CpG binding domain protein 3 like 1 19 8832398-8843340 Predicted intracellular proteins Evidence at protein level HPA043121, HPA046753 Supported Not detected Tissue enriched 5 testis: 34.5 fallopian tube: 6.4 Not detected +ZNF160 F11, FLJ00032, HKr18, HZF5, KIAA1611, KR18 ENSG00000170949 Zinc finger protein 160 19 53066606-53103436 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA023599 Uncertain Approved Nuclear speckles
Cytosol Urothelial cancer:2.67e-5 (favourable) Expressed in all Expressed in all spleen: 37.4 Mixed +PGK2 PGK-2, PGKPS ENSG00000170950 Phosphoglycerate kinase 2 6 49785651-49787307 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045385, HPA073644, HPA073656 Supported Not detected Tissue enriched 774 testis: 346.1 epididymis: 0.4 Not detected +OR8B12 ENSG00000170953 Olfactory receptor family 8 subfamily B member 12 11 124542682-124543679 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.3 Not detected +ZNF415 ENSG00000170954 Zinc finger protein 415 19 53107879-53133077 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005553 Approved Approved Nucleoli fibrillar center
Microtubules Mixed Mixed testis: 39.6 Cell line enhanced RT4: 17.7 +PRKCDBP cavin-3, CAVIN3, HSRBC, MGC20400, SRBC ENSG00000170955 Protein kinase C delta binding protein 11 6318946-6320647 Predicted intracellular proteins Evidence at protein level HPA055136, HPA073327 Approved Approved Plasma membrane Renal cancer:5.21e-6 (unfavourable), Cervical cancer:3.75e-5 (unfavourable) Expressed in all Mixed adipose tissue: 30.4 Cell line enhanced A-431: 88.2;BJ: 80.0;TIME: 91.9;U-87 MG: 101.1;WM-115: 110.6 +CEACAM3 CD66d, CGM1 ENSG00000170956 Carcinoembryonic antigen related cell adhesion molecule 3 19 41796437-41811553 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011041 Approved Not detected Tissue enriched 5 bone marrow: 28.5 appendix: 5.3 Not detected +DCDC1 ENSG00000170959 Doublecortin domain containing 1 11 30830369-31369810 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced fallopian tube: 6.6;testis: 4.2 gallbladder: 2.8 Cell line enhanced U-266/70: 1.1 +HAS2 ENSG00000170961 Hyaluronan synthase 2 8 121612116-121641390 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA052060 Approved Nuclear speckles Mixed Tissue enhanced adipose tissue: 27.9 gallbladder: 12.7 Cell line enhanced HBF TERT88: 154.7;hTEC/SVTERT24-B: 155.8;LHCN-M2: 174.3;U-138 MG: 396.2;U-251 MG: 103.0 +PDGFD IEGF, MSTP036, SCDGF-B ENSG00000170962 Platelet derived growth factor D 11 103907186-104164379 Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA046183, HPA066271 Approved Approved Golgi apparatus
Vesicles Stomach cancer:9.60e-4 (unfavourable) Expressed in all Tissue enhanced adrenal gland: 140.5;ovary: 96.6 gallbladder: 53.7 Group enriched 6 ASC diff: 96.8;HHSteC: 36.1 +PLAC1 CT92, OOSP2L ENSG00000170965 Placenta specific 1 X 134565838-134764322 Predicted secreted proteins Evidence at protein level HPA063425 Enhanced Mixed Tissue enriched 21 placenta: 37.7 testis: 1.7 Cell line enhanced HEK 293: 18.2;hTCEpi: 11.1 +DDI1 FLJ36017 ENSG00000170967 DNA damage inducible 1 homolog 1 11 104036580-104039188 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 283 testis: 28.2 all non-specific tissues: 0.0 Not detected +S1PR1 CD363, D1S3362, edg-1, EDG1 ENSG00000170989 Sphingosine-1-phosphate receptor 1 1 101236888-101241518 Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level CAB010104, HPA075568 Supported Supported Vesicles Urothelial cancer:8.78e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 86.8 Cell line enhanced BJ: 53.9;HUVEC TERT2: 149.1;TIME: 81.9;U-251 MG: 103.4 +HS6ST2 ENSG00000171004 Heparan sulfate 6-O-sulfotransferase 2 X 132626016-132961395 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA034625, HPA034626 Uncertain Supported Nucleoplasm Urothelial cancer:6.03e-4 (favourable) Mixed Tissue enhanced kidney: 15.0;ovary: 17.6 placenta: 11.9 Cell line enhanced HEK 293: 42.3;RH-30: 63.9;SH-SY5Y: 87.0 +OR4D5 ENSG00000171014 Olfactory receptor family 4 subfamily D member 5 11 123939543-123940637 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA045005 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +PYGO1 ENSG00000171016 Pygopus family PHD finger 1 15 55538890-55588947 Predicted intracellular proteins Evidence at protein level HPA042248 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced parathyroid gland: 29.9 thyroid gland: 12.0 Cell line enhanced U-698: 23.4 +LRRC8E FLJ23420 ENSG00000171017 Leucine rich repeat containing 8 family member E 19 7888505-7902021 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA020466 Uncertain Mixed Mixed skin: 11.0 Cell line enhanced U-87 MG: 35.6 +PKIA PRKACN1 ENSG00000171033 CAMP-dependent protein kinase inhibitor alpha 8 78516139-78605267 Predicted intracellular proteins Evidence at protein level HPA042791 Uncertain Stomach cancer:5.41e-4 (unfavourable) Mixed Tissue enhanced skeletal muscle: 407.4 heart muscle,parathyroid gland: 123.6 Cell line enhanced HUVEC TERT2: 86.5;RT4: 79.9 +XKR6 C8orf21, C8orf5, C8orf7 ENSG00000171044 XK related 6 8 10896045-11201366 Predicted membrane proteins Evidence at protein level HPA024828, HPA064769 Uncertain Approved Actin filaments Mixed Mixed testis: 1.8 Cell line enhanced U-266/84: 4.8 +TSNARE1 FLJ31164 ENSG00000171045 T-SNARE domain containing 1 8 142212080-142403240 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015890 Approved Nucleus Urothelial cancer:7.33e-4 (favourable) Expressed in all Expressed in all skin: 29.2 Mixed +FPR2 ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R ENSG00000171049 Formyl peptide receptor 2 19 51752026-51770526 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA029154 Approved Mixed Tissue enhanced appendix: 69.7 spleen: 19.7 Cell line enriched 21 U-937: 23.5 +FPR1 FMLP, FPR ENSG00000171051 Formyl peptide receptor 1 19 51745172-51804110 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA046550, HPA061744 Approved Approved Nucleus
Nucleoli
Golgi apparatus Renal cancer:2.21e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 177.8 bone marrow: 95.0 Cell line enriched 6 U-87 MG: 51.5 +PATE1 PATE ENSG00000171053 Prostate and testis expressed 1 11 125746293-125749867 Predicted secreted proteins Evidence at protein level HPA076587 Uncertain Not detected Tissue enriched 8 epididymis: 2299.3 seminal vesicle: 297.8 Cell line enhanced BEWO: 1.3;NB-4: 1.5 +OR13H1 ENSG00000171054 Olfactory receptor family 13 subfamily H member 1 X 131544074-131545000 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +FEZ2 ENSG00000171055 Fasciculation and elongation protein zeta 2 2 36531805-36646087 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035978 Uncertain Approved Nucleoli
Golgi apparatus
Cytosol Liver cancer:7.79e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 78.6 Expressed in all +SOX7 ENSG00000171056 SRY-box 7 8 10723768-10730512 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009065 Approved Approved Nuclear speckles
Golgi apparatus Expressed in all Tissue enhanced placenta: 49.6 lung: 18.7 Cell line enhanced HaCaT: 21.1;HUVEC TERT2: 46.6;TIME: 36.3 +C8orf74 ENSG00000171060 Chromosome 8 open reading frame 74 8 10672637-10700593 Predicted intracellular proteins Evidence at protein level HPA027986 Uncertain Uncertain Nucleoplasm Not detected Tissue enriched 42 testis: 12.4 skin: 0.2 Not detected +C11orf24 DM4E3 ENSG00000171067 Chromosome 11 open reading frame 24 11 68261335-68272001 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012748 Uncertain Uncertain Nucleoplasm
Vesicles Renal cancer:1.60e-9 (unfavourable), Lung cancer:6.05e-4 (unfavourable), Glioma:9.83e-4 (unfavourable) Expressed in all Expressed in all small intestine: 65.9 Expressed in all +ALK CD246 ENSG00000171094 Anaplastic lymphoma receptor tyrosine kinase 2 29192774-29921566 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010694 Approved Supported Plasma membrane Group enriched Tissue enhanced cerebral cortex: 2.7;testis: 2.0 adrenal gland: 0.5 Cell line enriched 6 SH-SY5Y: 28.3 +KYAT1 CCBL1, GTK, KATI ENSG00000171097 Kynurenine aminotransferase 1 9 128832942-128882494 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021176, HPA021177, HPA027736 Approved Enhanced Nucleoplasm
Cytosol Expressed in all Mixed cerebral cortex: 17.0 Expressed in all +MTM1 ENSG00000171100 Myotubularin 1 X 150568619-150673322 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA010008, HPA010665 Approved Supported Plasma membrane Renal cancer:7.40e-7 (favourable) Expressed in all Mixed parathyroid gland: 27.3 Expressed in all +OBP2B hOBPIIb, LCN14 ENSG00000171102 Odorant binding protein 2B 9 133205277-133209250 Predicted secreted proteins Evidence at protein level Group enriched Tissue enhanced breast: 1.8;testis: 6.8 fallopian tube: 1.4 Not detected +TRMT61B FLJ20628 ENSG00000171103 TRNA methyltransferase 61B 2 28849821-28870301 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026747, HPA026751 Enhanced Uncertain Cytosol Renal cancer:9.61e-5 (favourable), Liver cancer:3.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.5 Expressed in all +INSR CD220 ENSG00000171105 Insulin receptor 19 7112255-7294034 CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level HPA036302, HPA036303 Uncertain Approved Vesicles Expressed in all Expressed in all ovary: 35.5 Cell line enhanced Karpas-707: 42.9 +MFN1 FLJ20693 ENSG00000171109 Mitofusin 1 3 179347692-179394931 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB033437, HPA059230 Approved Supported Mitochondria Liver cancer:8.08e-5 (unfavourable), Endometrial cancer:6.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 20.4 Expressed in all +GIMAP8 DKFZp667I133, hIAN6, IAN9 ENSG00000171115 GTPase, IMAP family member 8 7 150450630-150479392 Predicted intracellular proteins Evidence at protein level HPA014474, HPA017765 Supported Testis cancer:8.47e-4 (unfavourable) Expressed in all Mixed spleen: 55.9 Cell line enriched 8 HUVEC TERT2: 49.3 +HSFX1 LW-1 ENSG00000171116 Heat shock transcription factor family, X-linked 1 X 149774068-149776867 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063040 Approved Not detected Mixed ovary: 4.6 Mixed +NRTN NTN ENSG00000171119 Neurturin 19 5823802-5828324 Disease related genes, Predicted secreted proteins Evidence at protein level Endometrial cancer:3.86e-4 (favourable), Head and neck cancer:7.23e-4 (favourable), Melanoma:9.92e-4 (favourable) Mixed Mixed heart muscle: 3.1 Cell line enhanced REH: 19.1;SH-SY5Y: 11.4;U-266/70: 8.7 +KCNMB3 KCNMB2, KCNMBL ENSG00000171121 Potassium calcium-activated channel subfamily M regulatory beta subunit 3 3 179236691-179267002 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA015665, HPA019185 Approved Approved Nucleus
Mitochondria Not detected Mixed placenta: 6.1 Cell line enhanced HEL: 7.2 +FUT3 CD174, LE ENSG00000171124 Fucosyltransferase 3 (Lewis blood group) 19 5842888-5851474 Blood group antigen proteins, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046966 Supported Renal cancer:8.22e-7 (favourable), Breast cancer:6.86e-4 (unfavourable) Tissue enhanced Tissue enhanced colon: 68.0;esophagus: 83.0;small intestine: 63.1 rectum: 49.4 Group enriched 5 A-431: 40.5;RH-30: 14.4 +KCNG3 Kv6.3 ENSG00000171126 Potassium voltage-gated channel modifier subfamily G member 3 2 42442017-42494097 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA041625 Approved Cytoplasmic bodies Mixed Tissue enhanced adrenal gland: 1.2;cerebral cortex: 1.3;testis: 1.1 colon,endometrium: 0.4 Cell line enhanced HAP1: 4.9;HMC-1: 14.2;NTERA-2: 10.3 +ATP6V0E2 ATP6V0E2L, C7orf32 ENSG00000171130 ATPase H+ transporting V0 subunit e2 7 149872968-149880698 Predicted membrane proteins Evidence at transcript level Renal cancer:8.26e-7 (favourable), Pancreatic cancer:5.80e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 261.0 Expressed in all +PRKCE ENSG00000171132 Protein kinase C epsilon 2 45651345-46187990 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB001948, HPA044496, HPA054252 Enhanced Approved Vesicles Renal cancer:2.63e-7 (favourable), Endometrial cancer:2.42e-4 (unfavourable), Lung cancer:9.62e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 48.3 parathyroid gland: 20.5 Mixed +OR2K2 HSHTPCRH06, HTPCRH06, OR2AR1P ENSG00000171133 Olfactory receptor family 2 subfamily K member 2 9 111327483-111328520 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA024261 Uncertain Not detected Not detected testis: 0.3 Not detected +JAGN1 FLJ14602, GL009 ENSG00000171135 Jagunal homolog 1 3 9890554-9894349 Disease related genes, Predicted membrane proteins Evidence at protein level HPA067610 Approved Vesicles Expressed in all Expressed in all epididymis: 37.9 Expressed in all +RLN3 H3, RXN3, ZINS4 ENSG00000171136 Relaxin 3 19 14028148-14031042 Predicted secreted proteins Evidence at protein level HPA043731 Uncertain Not detected Group enriched 6 parathyroid gland: 2.9;testis: 3.3 spleen: 0.5 Not detected +TADA3 ADA3, FLJ20221, FLJ21329, hADA3, NGG1, TADA3L ENSG00000171148 Transcriptional adaptor 3 3 9779860-9793011 Predicted intracellular proteins Evidence at protein level HPA042250 Approved Supported Nucleoplasm Renal cancer:5.47e-5 (favourable) Expressed in all Expressed in all testis: 71.9 Expressed in all +SOCS5 CIS6, Cish5, CISH6, KIAA0671, SOCS-5 ENSG00000171150 Suppressor of cytokine signaling 5 2 46698952-46763129 Predicted intracellular proteins Evidence at protein level HPA020884, CAB025510 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:7.28e-4 (unfavourable), Ovarian cancer:7.53e-4 (unfavourable) Expressed in all Expressed in all ovary: 31.1 Expressed in all +C1GALT1C1 C1GALT2, COSMC ENSG00000171155 C1GALT1 specific chaperone 1 X 120625793-120630150 Disease related genes, Predicted membrane proteins Evidence at protein level HPA015632 Approved Approved Cytosol Breast cancer:5.66e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 44.5 Expressed in all +C9orf16 EST00098, FLJ12823, MGC4639 ENSG00000171159 Chromosome 9 open reading frame 16 9 128160260-128163928 Predicted intracellular proteins Evidence at protein level HPA020725 Uncertain Approved Microtubules Liver cancer:3.13e-5 (unfavourable), Cervical cancer:7.60e-4 (favourable), Colorectal cancer:9.91e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 151.4 Expressed in all +MORN4 bA548K23.4, C10orf83, FLJ25925, rtp ENSG00000171160 MORN repeat containing 4 10 97614553-97633500 Predicted intracellular proteins Evidence at protein level HPA052718 Uncertain Expressed in all Expressed in all parathyroid gland: 32.1 Mixed +ZNF672 FLJ22301 ENSG00000171161 Zinc finger protein 672 1 248838210-248849517 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055779, HPA062506 Approved Enhanced Nucleoplasm Urothelial cancer:1.79e-5 (favourable), Pancreatic cancer:7.51e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 24.8 Expressed in all +ZNF692 AREBP, FLJ20531, Zfp692 ENSG00000171163 Zinc finger protein 692 1 248850006-248859144 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059337, HPA062792 Uncertain Enhanced Nucleus
Nucleoli Renal cancer:7.72e-9 (unfavourable), Urothelial cancer:8.35e-5 (favourable), Pancreatic cancer:4.09e-4 (favourable) Expressed in all Expressed in all testis: 26.8 Expressed in all +NAIF1 bA379C10.2, C9orf90, DKFZp762G199 ENSG00000171169 Nuclear apoptosis inducing factor 1 9 128061233-128068206 Predicted intracellular proteins Evidence at protein level HPA054898, HPA064931 Approved Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:1.02e-5 (favourable), Renal cancer:8.30e-5 (favourable), Liver cancer:1.61e-4 (unfavourable) Expressed in all Mixed testis: 4.6 Expressed in all +RBKS DKFZp686G13268, RBSK ENSG00000171174 Ribokinase 2 27781364-27891098 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019725, HPA028285 Enhanced Approved Cytosol Expressed in all Tissue enhanced adrenal gland: 34.7 kidney: 19.5 Cell line enhanced EFO-21: 10.8;RPTEC TERT1: 18.4 +OR2M4 HSHTPCRX18, HTPCRX18, OST710, TPCR100 ENSG00000171180 Olfactory receptor family 2 subfamily M member 4 1 248238929-248239864 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA051308 Uncertain Not detected Not detected cerebral cortex: 0.2 Not detected +GRIK1 GluK1, GLUR5 ENSG00000171189 Glutamate ionotropic receptor kainate type subunit 1 21 29536933-29940033 FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA014623 Uncertain Glioma:9.12e-4 (unfavourable) Group enriched Tissue enhanced adrenal gland: 16.3;cerebral cortex: 9.0 prostate: 4.0 Not detected +MUC7 FLJ27047, MG2 ENSG00000171195 Mucin 7, secreted 4 70430492-70482997 Disease related genes, Predicted secreted proteins Evidence at protein level HPA006411 Enhanced Group enriched Tissue enriched 1464 salivary gland: 11361.9 ovary: 7.7 Not detected +OPRPN BPLP, PRL1, PROL1 ENSG00000171199 Opiorphin prepropeptide 4 70397882-70410194 Predicted secreted proteins Evidence at protein level HPA065711 Approved Tissue enhanced Group enriched 10 breast: 33.1;salivary gland: 18.9 epididymis: 2.5 Not detected +SMR3B P-B, PRL3, PROL3 ENSG00000171201 Submaxillary gland androgen regulated protein 3B 4 70370093-70390244 Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 1608 salivary gland: 85397.1 ovary: 53.0 Cell line enriched 34 EFO-21: 3.9 +TMEM126A DKFZp586C1924, OPA7 ENSG00000171202 Transmembrane protein 126A 11 85647967-85656547 Disease related genes, Predicted membrane proteins Evidence at protein level HPA046648 Approved Approved Nucleus
Cytosol Liver cancer:8.60e-5 (unfavourable) Expressed in all Expressed in all testis: 67.3 Expressed in all +TMEM126B HT007 ENSG00000171204 Transmembrane protein 126B 11 85628573-85636539 Predicted membrane proteins Evidence at protein level HPA014480, HPA019186 Uncertain Supported Mitochondria Expressed in all Expressed in all epididymis: 39.6 Expressed in all +TRIM8 GERP, RNF27 ENSG00000171206 Tripartite motif containing 8 10 102644496-102658407 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023560, HPA023561 Approved Enhanced Nucleoplasm
Vesicles
Cytosol Expressed in all Expressed in all adipose tissue: 60.9 Expressed in all +NETO2 FLJ10430, NEOT2 ENSG00000171208 Neuropilin and tolloid like 2 16 47077703-47143997 Predicted membrane proteins, Transporters Evidence at protein level HPA013180 Uncertain Approved Golgi apparatus Renal cancer:5.53e-6 (unfavourable) Mixed Tissue enhanced spleen: 31.5 cerebral cortex: 20.9 Mixed +CSN3 CSN10 ENSG00000171209 Casein kappa 4 70242588-70251428 Predicted secreted proteins Evidence at protein level HPA035953, HPA035954 Enhanced Group enriched Tissue enriched 13 breast: 428.0 salivary gland: 32.0 Not detected +CLDN20 ENSG00000171217 Claudin 20 6 155264013-155276548 Predicted membrane proteins Evidence at transcript level Mixed Mixed skin: 1.0 Mixed +CDC42BPG DMPK2, HSMDPKIN, kappa-200, MRCKgamma ENSG00000171219 CDC42 binding protein kinase gamma 11 64823387-64844569 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027382, HPA061836 Enhanced Supported Cytosol Renal cancer:5.99e-13 (favourable) Mixed Tissue enhanced skin: 35.6 parathyroid gland: 14.5 Cell line enhanced BEWO: 30.1;HaCaT: 21.0;MCF7: 25.1;SCLC-21H: 19.6 +SCAND1 RAZ1, SDP1 ENSG00000171222 SCAN domain containing 1 20 35953617-35959472 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047138 Supported Nucleus
Actin filaments
Cytosol Expressed in all Expressed in all duodenum: 29.4 Expressed in all +JUNB ENSG00000171223 JunB proto-oncogene, AP-1 transcription factor subunit 19 12791496-12793315 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004464, HPA019149 Approved Enhanced Nucleoplasm Renal cancer:1.05e-4 (unfavourable), Ovarian cancer:3.65e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 320.7 Expressed in all +C10orf35 ENSG00000171224 Chromosome 10 open reading frame 35 10 69630251-69633599 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034591 Enhanced Approved Nucleus
Centrosome
Cytosol Liver cancer:1.03e-4 (unfavourable), Head and neck cancer:8.64e-4 (unfavourable), Urothelial cancer:9.72e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 27.6 testis: 20.2 Cell line enhanced PC-3: 53.3 +TMEM37 PR, PR1 ENSG00000171227 Transmembrane protein 37 2 119429901-119438520 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053794 Enhanced Approved Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all Mixed kidney: 108.5 Cell line enhanced EFO-21: 25.4;Hep G2: 50.5;RPTEC TERT1: 45.1 +UGT2B7 UGT2B9 ENSG00000171234 UDP glucuronosyltransferase family 2 member B7 4 69051363-69112987 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA045108 Uncertain Colorectal cancer:7.65e-5 (favourable), Renal cancer:3.79e-4 (favourable), Urothelial cancer:5.38e-4 (favourable) Group enriched Group enriched 13 kidney: 1326.3;liver: 825.7 fallopian tube: 79.7 Cell line enhanced EFO-21: 73.2;RPTEC TERT1: 235.7;U-2197: 40.2 +LRG1 LRG ENSG00000171236 Leucine rich alpha-2-glycoprotein 1 19 4536409-4540474 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001888, HPA001889 Enhanced Approved Vesicles Renal cancer:3.66e-6 (unfavourable), Thyroid cancer:3.49e-4 (favourable) Tissue enriched Tissue enriched 8 liver: 173.8 appendix,esophagus: 21.1 Cell line enhanced THP-1: 15.8;U-937: 34.0 +SHCBP1 FLJ22009, PAL ENSG00000171241 SHC binding and spindle associated 1 16 46580554-46621626 Predicted intracellular proteins Evidence at protein level HPA048876 Uncertain Approved Nuclear bodies
Microtubules
Cytokinetic bridge Pancreatic cancer:4.47e-5 (unfavourable) Mixed Tissue enhanced lymph node: 17.4 bone marrow: 16.7 Mixed +SOSTDC1 DAND7, DKFZp564D206, USAG1 ENSG00000171243 Sclerostin domain containing 1 7 16461481-16530580 Predicted secreted proteins Evidence at protein level Renal cancer:3.22e-5 (favourable), Ovarian cancer:8.69e-4 (favourable), Urothelial cancer:8.72e-4 (unfavourable) Tissue enhanced Tissue enhanced lung: 57.1;stomach: 53.4 kidney: 23.0 Cell line enhanced AF22: 8.0;EFO-21: 11.2;NTERA-2: 4.7;RPTEC TERT1: 16.9 +NPTX1 ENSG00000171246 Neuronal pentraxin 1 17 80467148-80477843 Predicted secreted proteins Evidence at protein level HPA077062 Enhanced Tissue enhanced Tissue enriched 28 cerebral cortex: 122.5 adrenal gland: 4.3 Cell line enhanced HAP1: 33.7;SiHa: 44.5;U-138 MG: 85.8;WM-115: 120.6 +FAM98B FLJ38426 ENSG00000171262 Family with sequence similarity 98 member B 15 38454127-38487710 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008320, HPA008502 Enhanced Supported Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 32.1 Expressed in all +ZNF439 DKFZp571K0837 ENSG00000171291 Zinc finger protein 439 19 11848726-11883750 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047845 Uncertain Uncertain Nucleus Mixed Mixed parathyroid gland: 25.5 Cell line enhanced U-138 MG: 15.4 +ZNF440 FLJ37933 ENSG00000171295 Zinc finger protein 440 19 11814284-11835201 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047845 Uncertain Uncertain Nucleus Renal cancer:1.18e-4 (favourable), Prostate cancer:3.57e-4 (unfavourable), Urothelial cancer:9.88e-4 (favourable) Expressed in all Mixed fallopian tube: 23.2 Mixed +GAA ENSG00000171298 Glucosidase alpha, acid 17 80101556-80119879 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026970, HPA029126 Enhanced Colorectal cancer:7.66e-4 (unfavourable) Expressed in all Expressed in all placenta: 69.7 Mixed +CANT1 SCAN-1, SHAPY ENSG00000171302 Calcium activated nucleotidase 1 17 78991717-79009867 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019627, HPA019639, HPA022818 Enhanced Liver cancer:1.41e-4 (unfavourable), Lung cancer:2.90e-4 (unfavourable), Renal cancer:6.21e-4 (unfavourable) Expressed in all Expressed in all prostate: 115.7 Expressed in all +KCNK3 K2p3.1, TASK, TASK-1 ENSG00000171303 Potassium two pore domain channel subfamily K member 3 2 26692690-26733420 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Renal cancer:2.37e-7 (unfavourable) Tissue enhanced Tissue enhanced adrenal gland: 111.8;placenta: 35.8 lung: 19.9 Group enriched 6 EFO-21: 10.3;SCLC-21H: 30.6 +ZDHHC16 APH2 ENSG00000171307 Zinc finger DHHC-type containing 16 10 97446131-97457370 Enzymes, Predicted membrane proteins Evidence at protein level HPA039893, HPA040214 Uncertain Supported Nucleus
Nuclear membrane
Cytosol Expressed in all Expressed in all parathyroid gland,placenta: 31.5 Expressed in all +CHST11 C4ST, C4St-1, C4ST1, HSA269537 ENSG00000171310 Carbohydrate sulfotransferase 11 12 104455295-104762014 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA052828 Approved Approved Golgi apparatus Renal cancer:7.59e-11 (unfavourable), Urothelial cancer:8.42e-4 (unfavourable) Expressed in all Mixed appendix: 27.6 Mixed +EXOSC1 CGI-108, CSL4, Csl4p, hCsl4p, p13, SKI4, Ski4p ENSG00000171311 Exosome component 1 10 97436142-97446017 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038370 Approved Approved Nucleoplasm
Nuclear bodies Renal cancer:3.88e-9 (unfavourable) Expressed in all Expressed in all epididymis: 54.6 Expressed in all +PGAM1 PGAM-B, PGAMA ENSG00000171314 Phosphoglycerate mutase 1 10 97426160-97433441 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042528, HPA060483 Approved Approved Nucleoplasm Breast cancer:2.04e-4 (unfavourable), Cervical cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 421.2 Expressed in all +CHD7 CRG, FLJ20357, FLJ20361, KIAA1416 ENSG00000171316 Chromodomain helicase DNA binding protein 7 8 60678778-60868028 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA053075 Supported Nucleoplasm
Nucleoli Endometrial cancer:5.34e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 14.6 Cell line enhanced AF22: 50.9;SCLC-21H: 55.1 +ESCO2 EFO2, RBS ENSG00000171320 Establishment of sister chromatid cohesion N-acetyltransferase 2 8 27771949-27812640 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027243, HPA053679 Supported Nucleus
Golgi apparatus Colorectal cancer:1.04e-4 (favourable) Mixed Tissue enhanced duodenum: 11.2 testis: 10.4 Mixed +KRT19 CK19, K19, K1CS, MGC15366 ENSG00000171345 Keratin 19 17 41523617-41528308 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000031, HPA002465 Enhanced Supported Intermediate filaments Renal cancer:2.98e-5 (unfavourable), Pancreatic cancer:6.82e-5 (unfavourable) Mixed Mixed urinary bladder: 678.5 Cell line enhanced HBEC3-KT: 2110.1;RT4: 2508.0;SK-BR-3: 4076.0;T-47d: 3451.5 +KRT15 CK15, K15, K1CO ENSG00000171346 Keratin 15 17 41513743-41522529 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023910, HPA024554 Enhanced Supported Nucleoplasm
Intermediate filaments Breast cancer:4.50e-4 (favourable) Tissue enhanced Group enriched 7 breast: 321.5;esophagus: 784.4;skin: 1010.3 prostate: 94.7 Group enriched 12 HaCaT: 732.6;hTCEpi: 454.1 +LURAP1 C1orf190, FLJ25163, LRAP35a ENSG00000171357 Leucine rich adaptor protein 1 1 46203334-46221261 Predicted intracellular proteins Evidence at protein level HPA030060, HPA030061 Uncertain Approved Vesicles Renal cancer:8.81e-8 (favourable) Mixed Tissue enhanced parathyroid gland: 18.1;thyroid gland: 17.6 testis: 9.2 Mixed +KRT38 KRTHA8 ENSG00000171360 Keratin 38 17 41436446-41440921 Plasma proteins, Predicted intracellular proteins Evidence at protein level Group enriched Not detected tonsil: 0.3 Not detected +CLCN5 ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN ENSG00000171365 Chloride voltage-gated channel 5 X 49922615-50099235 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000401, HPA003213 Uncertain Supported Golgi apparatus
Plasma membrane
Cytosol Renal cancer:2.05e-8 (favourable), Pancreatic cancer:5.20e-4 (favourable) Expressed in all Tissue enhanced epididymis: 33.7;kidney: 52.0 placenta: 9.6 Cell line enhanced CACO-2: 44.1;RH-30: 76.7 +TPPP p25, p25alpha, TPPP/p25, TPPP1 ENSG00000171368 Tubulin polymerization promoting protein 5 659862-693395 Predicted intracellular proteins Evidence at protein level HPA036575, HPA036576 Enhanced Supported Mitochondria
Cytosol Renal cancer:5.40e-6 (favourable) Expressed in all Tissue enriched 10 cerebral cortex: 166.6 fallopian tube: 16.9 Cell line enhanced A549: 6.6;AN3-CA: 5.0;SCLC-21H: 15.6 +KCND3 KSHIVB, Kv4.3, SCA19, SCA22 ENSG00000171385 Potassium voltage-gated channel subfamily D member 3 1 111770662-111989155 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA029452 Approved Mixed Mixed cerebral cortex: 26.7 Cell line enhanced SCLC-21H: 14.0;WM-115: 2.8 +APLN apelin, XNPEP2 ENSG00000171388 Apelin X 129645259-129654937 Predicted secreted proteins Evidence at transcript level Renal cancer:9.61e-5 (unfavourable), Cervical cancer:2.92e-4 (unfavourable), Lung cancer:6.09e-4 (unfavourable), Liver cancer:9.32e-4 (unfavourable) Group enriched Tissue enhanced placenta: 79.6 lung: 20.8 Cell line enriched 6 HUVEC TERT2: 421.2 +KRTAP4-4 KAP4.13, KAP4.4, KRTAP4-13 ENSG00000171396 Keratin associated protein 4-4 17 41159651-41160731 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRT13 CK13, K13, MGC161462, MGC3781 ENSG00000171401 Keratin 13 17 41500981-41505705 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000133, HPA030877, HPA069771 Enhanced Enhanced Intermediate filaments Renal cancer:1.45e-6 (unfavourable), Pancreatic cancer:1.02e-4 (unfavourable) Group enriched Tissue enriched 20 esophagus: 35138.5 tonsil: 1728.2 Group enriched 134 A-431: 2202.2;HaCaT: 1446.9 +XAGE3 CT12.3a, CT12.3b, GAGED4, PLAC6, pp9012, XAGE-3 ENSG00000171402 X antigen family member 3 X 52862525-52868068 Predicted intracellular proteins Evidence at protein level HPA052507, HPA059045, HPA060900 Approved Mixed Tissue enriched 167 placenta: 575.4 adipose tissue: 3.4 Cell line enhanced BEWO: 1.2;U-266/70: 1.6;U-266/84: 1.4 +KRT9 CK-9, EPPK, K9 ENSG00000171403 Keratin 9 17 41565841-41572058 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007261, CAB037322 Supported Tissue enriched Tissue enhanced skin: 2.9 adrenal gland: 0.7 Cell line enhanced BEWO: 6.7;HaCaT: 14.8;U-937: 4.1 +XAGE5 CT12.5, GAGED5, XAGE-5 ENSG00000171405 X antigen family member 5 X 52812204-52818301 Predicted intracellular proteins Evidence at transcript level HPA052507, HPA055941, HPA059045 Uncertain Approved Nucleoplasm
Vesicles Tissue enhanced Tissue enriched 10 testis: 2.1 skin: 0.2 Cell line enriched 47 U-2 OS: 22.9 +PDE7B ENSG00000171408 Phosphodiesterase 7B 6 135851696-136195574 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA023967 Uncertain Approved Nucleoplasm Renal cancer:1.59e-4 (favourable) Mixed Mixed ovary: 16.2 Cell line enhanced EFO-21: 15.3;HSkMC: 16.3;U-2197: 10.6 +MRPL36 BRIP1, L36mt, MRP-L36, PRPL36, RPMJ ENSG00000171421 Mitochondrial ribosomal protein L36 5 1798386-1801366 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047238 Approved Supported Nuclear bodies
Mitochondria Renal cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all testis: 95.6 Expressed in all +ZNF581 FLJ22550, HSPC189 ENSG00000171425 Zinc finger protein 581 19 55635459-55645622 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059657 Uncertain Liver cancer:5.74e-5 (unfavourable) Expressed in all Expressed in all ovary: 21.7 Expressed in all +NAT1 AAC1 ENSG00000171428 N-acetyltransferase 1 8 18170477-18223689 Enzymes, Predicted intracellular proteins Evidence at protein level CAB017782, HPA043704 Approved Colorectal cancer:5.07e-4 (favourable) Tissue enriched Mixed epididymis: 18.4 Mixed +KRT20 CK20, K20, MGC35423 ENSG00000171431 Keratin 20 17 40875941-40885227 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000032, HPA024309, HPA024684, HPA027236 Enhanced Supported Cytosol Renal cancer:1.32e-4 (unfavourable), Liver cancer:7.05e-4 (unfavourable) Group enriched Tissue enhanced colon: 356.1;duodenum: 252.4;rectum: 295.3;small intestine: 499.6 stomach: 82.3 Cell line enhanced BEWO: 1.0;RT4: 2.3 +GLOD5 ENSG00000171433 Glyoxalase domain containing 5 X 48761750-48773648 Predicted intracellular proteins Evidence at protein level HPA010667 Uncertain Uncertain Mitochondria Mixed Tissue enhanced duodenum: 10.8;kidney: 11.0;small intestine: 10.7 epididymis: 6.8 Cell line enhanced MCF7: 1.6 +KSR2 FLJ25965 ENSG00000171435 Kinase suppressor of ras 2 12 117453012-117968983 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA035536 Approved Not detected Tissue enhanced cerebral cortex: 4.1 adrenal gland: 1.2 Group enriched 6 HUVEC TERT2: 3.8;SCLC-21H: 3.8;TIME: 5.6 +ZNF524 MGC23143 ENSG00000171443 Zinc finger protein 524 19 55600022-55603138 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050981 Uncertain Approved Nucleus Urothelial cancer:4.98e-8 (favourable) Expressed in all Expressed in all spleen: 15.7 Mixed +MCC ENSG00000171444 Mutated in colorectal cancers 5 113022099-113488830 Predicted intracellular proteins Evidence at protein level HPA037390, HPA037391 Approved Approved Supported Nucleoplasm Renal cancer:6.19e-4 (favourable) Expressed in all Tissue enhanced ovary: 87.5;parathyroid gland: 66.9 skin: 25.1 Cell line enhanced HBEC3-KT: 39.0 +KRT27 KRT25C ENSG00000171446 Keratin 27 17 40776808-40782534 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055114 Supported Tissue enhanced Tissue enhanced breast: 1.3 skin,testis: 0.4 Cell line enhanced EFO-21: 1.3 +ZBTB26 ZNF481 ENSG00000171448 Zinc finger and BTB domain containing 26 9 122915566-122931500 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021444 Uncertain Expressed in all Mixed testis: 18.2 Expressed in all +CDK5R2 NCK5AI, P39, p39nck5ai ENSG00000171450 Cyclin dependent kinase 5 regulatory subunit 2 2 218959655-218962162 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 10 cerebral cortex: 52.1 adrenal gland: 5.1 Group enriched 10 SCLC-21H: 21.4;SH-SY5Y: 14.0 +DSEL C18orf4, FLJ11477, NCAG1 ENSG00000171451 Dermatan sulfate epimerase-like 18 67506582-67516980 Predicted membrane proteins Evidence at protein level HPA060942 Approved Nucleoplasm
Plasma membrane Tissue enhanced Mixed cerebral cortex: 5.2 Cell line enhanced BJ: 31.6;LHCN-M2: 38.7;U-138 MG: 46.6 +POLR1C RPA39, RPA40, RPA5, RPAC1 ENSG00000171453 RNA polymerase I subunit C 6 43509702-43529585 Disease related genes, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA031010 Supported Nucleus Renal cancer:4.17e-4 (unfavourable) Expressed in all Expressed in all testis: 34.5 Expressed in all +ASXL1 KIAA0978 ENSG00000171456 Additional sex combs like 1, transcriptional regulator 20 32358344-32439319 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064156 Approved Nucleus
Nucleoli Endometrial cancer:2.86e-4 (unfavourable), Head and neck cancer:9.16e-4 (favourable) Expressed in all Expressed in all testis: 68.5 Expressed in all +OR1L6 OR1L7 ENSG00000171459 Olfactory receptor family 1 subfamily L member 6 9 122749740-122750783 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +DLK2 EGFL9, MGC2487 ENSG00000171462 Delta like non-canonical Notch ligand 2 6 43450352-43456632 Predicted membrane proteins Evidence at transcript level HPA061223, HPA068672 Uncertain Approved Nucleus Mixed Tissue enhanced prostate: 9.3;skin: 14.5 seminal vesicle: 7.5 Cell line enhanced HaCaT: 21.0;hTCEpi: 27.7 +ZNF562 FLJ20079 ENSG00000171466 Zinc finger protein 562 19 9641808-9675086 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055332, HPA062397 Uncertain Approved Nucleoplasm Head and neck cancer:4.17e-4 (favourable) Expressed in all Expressed in all esophagus: 18.7 Expressed in all +ZNF318 HRIHFB2436, ZFP318 ENSG00000171467 Zinc finger protein 318 6 43307134-43369478 Predicted intracellular proteins Evidence at protein level HPA027022, HPA027031 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 49.6 Expressed in all +ZNF561 MGC45408 ENSG00000171469 Zinc finger protein 561 19 9604680-9621399 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055332, HPA062397 Uncertain Approved Nucleoplasm Renal cancer:1.16e-4 (favourable), Ovarian cancer:1.31e-4 (favourable) Expressed in all Expressed in all smooth muscle: 38.2 Mixed +WIPF2 WICH, WIRE ENSG00000171475 WAS/WASL interacting protein family member 2 17 40219304-40284136 Predicted intracellular proteins Evidence at protein level HPA024000, HPA024001, HPA024467 Enhanced Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 32.4 Expressed in all +HOPX HOP, LAGY, NECC1, OB1, SMAP31 ENSG00000171476 HOP homeobox 4 56647988-56681899 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB018632, HPA030180 Enhanced Mixed Tissue enhanced epididymis: 658.1;skin: 839.4 esophagus: 525.5 Cell line enhanced HDLM-2: 28.9;HUVEC TERT2: 55.7;RT4: 40.2;TIME: 62.0 +SPACA5B LYZL5B ENSG00000171478 Sperm acrosome associated 5B X 48130657-48132613 Enzymes, Predicted secreted proteins Evidence at protein level HPA044747, HPA047149 Supported Not detected Tissue enriched 149 testis: 16.5 fallopian tube: 0.1 Not detected +OR1L3 OR9-D ENSG00000171481 Olfactory receptor family 1 subfamily L member 3 9 122675130-122676104 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA058878 Uncertain Not detected Not detected cerebral cortex: 0.1 Not detected +NLRP5 CLR19.8, MATER, NALP5, PAN11, PYPAF8 ENSG00000171487 NLR family pyrin domain containing 5 19 55999726-56061813 Predicted secreted proteins Evidence at protein level HPA056271 Uncertain Not detected Tissue enriched 51 parathyroid gland: 22.9 testis: 0.4 Cell line enhanced U-2 OS: 3.9 +LRRC8C AD158 ENSG00000171488 Leucine rich repeat containing 8 family member C 1 89633072-89769903 Predicted membrane proteins, Transporters Evidence at protein level HPA029347 Uncertain Approved Golgi apparatus Renal cancer:3.75e-4 (unfavourable) Expressed in all Mixed smooth muscle: 22.7 Mixed +SPACA5 dJ54B20.3, LYC5, LYZL5, PNPK6288, SLLP2, UNQ6288 ENSG00000171489 Sperm acrosome associated 5 X 48004336-48009729 Enzymes, Predicted secreted proteins Evidence at protein level HPA044747, HPA047149 Supported Not detected Tissue enriched 10 testis: 13.6 thyroid gland: 1.4 Not detected +RSL1D1 CSIG, DKFZP564M182, L12, PBK1, UTP30 ENSG00000171490 Ribosomal L1 domain containing 1 16 11833850-11851585 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043483 Supported Enhanced Nucleoli Liver cancer:1.38e-4 (unfavourable), Head and neck cancer:2.95e-4 (unfavourable), Renal cancer:3.24e-4 (unfavourable) Expressed in all Expressed in all ovary: 145.4 Expressed in all +LRRC8D FLJ10470, LRRC5 ENSG00000171492 Leucine rich repeat containing 8 family member D 1 89821014-89936611 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014745 Approved Nucleoplasm
Mitochondria Endometrial cancer:3.21e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 35.9 Expressed in all +MROH2B DKFZp781F0822, FLJ40243, HEATR7B2 ENSG00000171495 Maestro heat like repeat family member 2B 5 40998017-41071342 Predicted intracellular proteins Evidence at protein level HPA059457 Supported Tissue enriched Tissue enriched 418 testis: 41.8 all non-specific tissues: 0.0 Not detected +OR1L8 ENSG00000171496 Olfactory receptor family 1 subfamily L member 8 9 122567548-122568477 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced spleen: 1.2 testis: 0.8 Cell line enriched 7 RT4: 5.5 +PPID CYP-40 ENSG00000171497 Peptidylprolyl isomerase D 4 158709134-158723396 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019520, HPA019692 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all duodenum: 50.9 Expressed in all +OR1N2 ENSG00000171501 Olfactory receptor family 1 subfamily N member 2 9 122553112-122555173 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +COL24A1 ENSG00000171502 Collagen type XXIV alpha 1 chain 1 85729233-86156943 Predicted secreted proteins Evidence at protein level Mixed Mixed cervix, uterine: 3.5 Cell line enhanced Karpas-707: 2.7;NTERA-2: 1.9;RH-30: 2.6;U-266/70: 5.3 +ETFDH ETFQO ENSG00000171503 Electron transfer flavoprotein dehydrogenase 4 158672125-158709623 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041978 Enhanced Renal cancer:5.76e-10 (favourable) Expressed in all Expressed in all liver: 99.7 Expressed in all +OR1N1 OR1-26, OR1N3 ENSG00000171505 Olfactory receptor family 1 subfamily N member 1 9 122526358-122527296 G-protein coupled receptors, Predicted membrane proteins No evidence Group enriched Not detected cervix, uterine,testis: 0.1 Not detected +RXFP1 LGR7, RXFPR1 ENSG00000171509 Relaxin/insulin like family peptide receptor 1 4 158315311-158653372 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA027067 Approved Tissue enriched Tissue enhanced cerebral cortex: 21.6;endometrium: 10.1 adrenal gland: 5.7 Group enriched 6 EFO-21: 26.8;HEL: 8.8;RPTEC TERT1: 10.0 +LPAR3 Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3 ENSG00000171517 Lysophosphatidic acid receptor 3 1 84811602-84893213 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013421 Supported Plasma membrane Ovarian cancer:4.31e-5 (favourable) Tissue enhanced Tissue enhanced fallopian tube: 66.9 prostate: 23.3 Cell line enhanced HAP1: 22.1;HBEC3-KT: 18.9;hTCEpi: 20.1;NTERA-2: 23.5;PC-3: 24.6;SK-MEL-30: 19.8 +PTGER4 EP4 ENSG00000171522 Prostaglandin E receptor 4 5 40679498-40693735 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA011226, HPA012756 Approved Urothelial cancer:2.48e-4 (favourable) Expressed in all Expressed in all bone marrow: 48.1 Cell line enhanced HDLM-2: 33.9;RT4: 28.7;TIME: 37.0 +TBCA ENSG00000171530 Tubulin folding cofactor A 5 77691166-77868780 Predicted intracellular proteins Evidence at protein level HPA036487 Approved Supported Nucleoli
Microtubules Expressed in all Expressed in all adrenal gland: 305.8 Expressed in all +NEUROD2 bHLHa1, NDRF ENSG00000171532 Neuronal differentiation 2 17 39603536-39609777 Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enhanced Tissue enriched 142 cerebral cortex: 14.9 stomach: 0.1 Cell line enriched 302 SCLC-21H: 30.2 +MAP6 FLJ41346, KIAA1878, MAP6-N, STOP ENSG00000171533 Microtubule associated protein 6 11 75586918-75669120 Predicted intracellular proteins Evidence at protein level CAB015442, CAB022600, HPA039061, HPA039062 Enhanced Uncertain Plasma membrane Pancreatic cancer:3.41e-4 (favourable), Prostate cancer:9.15e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 68.1;fallopian tube: 65.5 parathyroid gland: 52.6 Group enriched 6 AF22: 37.3;CACO-2: 31.4;HDLM-2: 19.9;SCLC-21H: 73.4;SH-SY5Y: 33.6 +OTP ENSG00000171540 Orthopedia homeobox 5 77628712-77639688 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059342 Supported Tissue enriched Not detected lung,testis: 0.1 Not detected +ECEL1 DINE, XCE ENSG00000171551 Endothelin converting enzyme like 1 2 232479827-232487828 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067560, HPA069756 Supported Approved Nucleoplasm
Nuclear membrane
Nucleoli Tissue enhanced Tissue enriched 25 ovary: 111.9 spleen: 4.4 Group enriched 7 AN3-CA: 40.8;HeLa: 15.2 +BCL2L1 Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52 ENSG00000171552 BCL2 like 1 20 31664452-31723989 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters Evidence at protein level HPA035734, CAB072801 Approved Approved Mitochondria Renal cancer:8.89e-5 (favourable), Pancreatic cancer:5.87e-4 (unfavourable), Endometrial cancer:9.10e-4 (unfavourable), Melanoma:9.57e-4 (favourable) Expressed in all Expressed in all gallbladder: 100.5 Expressed in all +FGG ENSG00000171557 Fibrinogen gamma chain 4 154604134-154612967 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027529, CAB033120 Supported Renal cancer:1.00e-6 (unfavourable) Tissue enriched Tissue enriched 115 liver: 8699.0 lung: 75.7 Cell line enriched 42 Hep G2: 503.3 +FGA ENSG00000171560 Fibrinogen alpha chain 4 154583126-154590766 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB016776, HPA051370, HPA064755 Supported Renal cancer:4.23e-6 (unfavourable), Liver cancer:7.33e-4 (favourable) Tissue enriched Tissue enriched 237 liver: 9265.4 stomach: 39.0 Cell line enriched 11 Hep G2: 285.6 +OR2AT4 ENSG00000171561 Olfactory receptor family 2 subfamily AT member 4 11 75088713-75089754 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA060357 Uncertain Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 12 K-562: 2.6 +FGB ENSG00000171564 Fibrinogen beta chain 4 154562956-154571086 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001900, HPA001901, CAB008624 Enhanced Enhanced Endoplasmic reticulum Renal cancer:5.72e-5 (unfavourable) Tissue enriched Tissue enriched 556 liver: 10006.0 kidney: 17.9 Cell line enriched 9 Hep G2: 184.1 +PLRG1 Cwc1, PRL1, Prp46, PRPF46, TANGO4 ENSG00000171566 Pleiotropic regulator 1 4 154535006-154550435 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035931, HPA035932, HPA061486 Supported Enhanced Nuclear membrane
Nuclear speckles Renal cancer:8.20e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 67.1 Expressed in all +ZNF584 FLJ39899 ENSG00000171574 Zinc finger protein 584 19 58401504-58418327 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at transcript level HPA043408, HPA048075 Uncertain Approved Nuclear speckles Expressed in all Mixed fallopian tube: 10.1 Mixed +DSCAM CHD2-42, CHD2-52 ENSG00000171587 DS cell adhesion molecule 21 40010999-40847139 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA019324 Enhanced Approved Nucleoplasm
Cytosol Tissue enriched Tissue enriched 11 cerebral cortex: 12.4 placenta,spleen: 1.0 Cell line enhanced HBEC3-KT: 2.6;MCF7: 6.2;NTERA-2: 2.2;SCLC-21H: 3.9;T-47d: 2.0 +DNAI2 CILD9, DIC2 ENSG00000171595 Dynein axonemal intermediate chain 2 17 74274247-74314884 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB006245, HPA050565 Enhanced Tissue enhanced Group enriched 8 fallopian tube: 48.0;testis: 27.7 lung: 4.6 Cell line enhanced HMC-1: 1.6 +NMUR1 FM-3, GPC-R, GPR66, NMU1R ENSG00000171596 Neuromedin U receptor 1 2 231523160-231530495 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level HPA027895 Uncertain Mixed Mixed adipose tissue: 5.5 Not detected +CLSTN1 CDHR12, CSTN1, KIAA0911 ENSG00000171603 Calsyntenin 1 1 9729026-9824526 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA012412 Approved Renal cancer:4.10e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 381.7 Expressed in all +CXXC5 HSPC195, RINF, WID ENSG00000171604 CXXC finger protein 5 5 139647299-139683882 Predicted intracellular proteins Evidence at protein level HPA036508, HPA058148 Approved Enhanced Nucleoplasm
Cytosol Endometrial cancer:4.10e-7 (unfavourable), Colorectal cancer:2.40e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 99.3 Expressed in all +ZNF274 ZKSCAN19, ZSCAN51 ENSG00000171606 Zinc finger protein 274 19 58183029-58213562 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028880 Uncertain Supported Nucleus
Centrosome Prostate cancer:1.75e-4 (unfavourable), Glioma:4.26e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 40.2 Expressed in all +PIK3CD p110D ENSG00000171608 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 1 9651732-9729114 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB015420, HPA044953 Enhanced Approved Vesicles
Cytokinetic bridge Expressed in all Tissue enhanced lymph node: 56.4 spleen: 51.2 Cell line enhanced HDLM-2: 146.7;REH: 64.7;U-937: 63.7 +PTCRA PT-ALPHA, PTA ENSG00000171611 Pre T-cell antigen receptor alpha 6 42915989-42925835 Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced lymph node: 3.2;spleen: 4.8 lung: 2.1 Group enriched 12 MOLT-4: 33.3;SK-MEL-30: 10.7 +SLC25A33 BMSC-MCP, MGC4399, PNC1 ENSG00000171612 Solute carrier family 25 member 33 1 9539482-9585179 Predicted membrane proteins, Transporters Evidence at protein level HPA049982 Uncertain Cervical cancer:4.86e-4 (favourable), Lung cancer:7.02e-4 (favourable) Expressed in all Mixed testis: 22.1 Expressed in all +ENC1 ENC-1, KLHL37, NRPB, PIG10, TP53I10 ENSG00000171617 Ectodermal-neural cortex 1 5 74627406-74641424 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA078061 Uncertain Plasma membrane Renal cancer:2.95e-5 (unfavourable), Breast cancer:3.88e-4 (unfavourable) Expressed in all Tissue enriched 15 cerebral cortex: 461.4 gallbladder: 30.8 Mixed +SPSB1 SSB-1 ENSG00000171621 SplA/ryanodine receptor domain and SOCS box containing 1 1 9292880-9369532 Predicted intracellular proteins Evidence at protein level Renal cancer:1.08e-6 (unfavourable) Expressed in all Mixed adipose tissue: 62.2 Cell line enhanced hTEC/SVTERT24-B: 81.5 +P2RY6 P2Y6 ENSG00000171631 Pyrimidinergic receptor P2Y6 11 73264505-73298617 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB022740 Uncertain Renal cancer:2.50e-7 (unfavourable) Mixed Tissue enhanced placenta: 16.8;spleen: 35.6 appendix: 10.8 Cell line enhanced AN3-CA: 64.0;EFO-21: 20.2;MCF7: 25.4;SK-BR-3: 41.5 +BPTF FAC1, FALZ, NURF301 ENSG00000171634 Bromodomain PHD finger transcription factor 17 67825524-67984378 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029069, HPA048289 Approved Enhanced Nucleoplasm Renal cancer:8.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 67.6 Expressed in all +S100Z Gm625, S100-zeta ENSG00000171643 S100 calcium binding protein Z 5 76850001-76921650 Predicted intracellular proteins Evidence at protein level HPA051929 Approved Tissue enhanced Mixed spleen: 3.3 Cell line enriched 6 U-698: 55.6 +ZIK1 ZNF762 ENSG00000171649 Zinc finger protein interacting with K protein 1 19 57578456-57593777 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA059975 Uncertain Approved Intermediate filaments Mixed Mixed parathyroid gland: 12.2 Cell line enhanced HEK 293: 26.5;NTERA-2: 34.3 +GPR82 ENSG00000171657 G protein-coupled receptor 82 X 41724155-41730135 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA035914 Approved Mixed Tissue enhanced tonsil: 6.3 lymph node: 3.7 Cell line enriched 16 HMC-1: 3.6 +GPR34 ENSG00000171659 G protein-coupled receptor 34 X 41688973-41697277 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA010668, CAB025490 Uncertain Uncertain Nucleus
Cytosol Expressed in all Mixed placenta: 60.9 Cell line enhanced HMC-1: 1.1 +PLEKHG5 GEF720, KIAA0720, Syx, Tech ENSG00000171680 Pleckstrin homology and RhoGEF domain containing G5 1 6466092-6520061 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049570 Uncertain Approved Nucleus Glioma:8.72e-4 (unfavourable) Expressed in all Tissue enhanced skin: 110.9 spleen: 34.6 Mixed +ATF7IP FLJ10688, p621 ENSG00000171681 Activating transcription factor 7 interacting protein 12 14365632-14502935 Predicted intracellular proteins Evidence at protein level HPA016578, HPA023505 Enhanced Enhanced Nucleoplasm
Nuclear bodies Glioma:7.91e-4 (favourable) Expressed in all Expressed in all testis: 61.7 Expressed in all +LKAAEAR1 C20orf201 ENSG00000171695 LKAAEAR motif containing 1 20 64083380-64084359 Predicted intracellular proteins Evidence at transcript level HPA056463 Uncertain Approved Nucleus Mixed Tissue enhanced testis: 2.7 cerebral cortex: 0.8 Cell line enhanced REH: 5.1;SCLC-21H: 6.5 +RGS19 GAIP, RGSGAIP ENSG00000171700 Regulator of G-protein signaling 19 20 64073181-64079988 Predicted intracellular proteins Evidence at protein level HPA056384, HPA069984 Enhanced Supported Nucleoli fibrillar center
Cell Junctions Renal cancer:2.06e-9 (unfavourable), Liver cancer:2.75e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 53.7 lymph node: 39.8 Expressed in all +TCEA2 TFIIS ENSG00000171703 Transcription elongation factor A2 20 64049836-64072347 Predicted intracellular proteins Evidence at protein level HPA043836 Approved Supported Nucleoplasm
Centrosome Expressed in all Expressed in all cerebral cortex: 73.8 Expressed in all +DEFB4A DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1 ENSG00000171711 Defensin beta 4A 8 7894629-7896711 Predicted secreted proteins, Transporters Evidence at protein level Group enriched Group enriched 8 esophagus: 6.0;gallbladder: 10.4;tonsil: 12.3 cervix, uterine: 1.2 Cell line enhanced EFO-21: 2.4 +ANO5 GDD1, LGMD2L, TMEM16E ENSG00000171714 Anoctamin 5 11 22193176-22283357 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA058857 Uncertain Renal cancer:2.50e-7 (favourable) Mixed Tissue enhanced parathyroid gland: 56.1 skeletal muscle: 23.6 Cell line enhanced A549: 4.5;HAP1: 5.6;HEK 293: 6.2 +HDAC3 HD3, RPD3, RPD3-2 ENSG00000171720 Histone deacetylase 3 5 141620876-141636870 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB005583, HPA052052 Supported Supported Nucleoplasm
Golgi apparatus Renal cancer:2.65e-6 (unfavourable), Colorectal cancer:3.39e-4 (favourable), Pancreatic cancer:3.95e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 52.1 Expressed in all +SPATA46 C1orf111 ENSG00000171722 Spermatogenesis associated 46 1 162373203-162376870 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 7 testis: 28.9 adrenal gland: 4.2 Cell line enhanced SCLC-21H: 1.1 +GPHN KIAA1385 ENSG00000171723 Gephyrin 14 66507407-67181803 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003116, CAB004419, HPA024694 Enhanced Uncertain Cytoplasmic bodies Renal cancer:5.25e-12 (favourable), Urothelial cancer:4.61e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 30.5 Mixed +VAT1L KIAA1576 ENSG00000171724 Vesicle amine transport 1 like 16 77788530-77980107 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044061, CAB046032 Enhanced Approved Cytosol Renal cancer:3.01e-6 (unfavourable) Tissue enhanced Group enriched 6 adrenal gland: 90.6;cerebral cortex: 38.8 heart muscle: 10.3 Cell line enhanced BJ hTERT+: 55.2;fHDF/TERT166: 29.2;NTERA-2: 79.1;U-87 MG: 80.3 +TMEM51 C1orf72, FLJ10199 ENSG00000171729 Transmembrane protein 51 1 15152532-15220480 Predicted membrane proteins Evidence at protein level HPA014547, HPA019441 Approved Approved Nucleoplasm
Cytosol Renal cancer:8.16e-8 (favourable) Expressed in all Mixed gallbladder: 33.4 Mixed +CAMTA1 KIAA0833 ENSG00000171735 Calmodulin binding transcription activator 1 1 6785324-7769706 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036342, HPA036343 Approved Supported Nucleoli
Cytosol Ovarian cancer:4.10e-4 (favourable), Liver cancer:5.25e-4 (unfavourable) Expressed in all Expressed in all epididymis: 99.9 Expressed in all +LGALS4 GAL4 ENSG00000171747 Galectin 4 19 38801671-38813364 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB025653, HPA031184, HPA031185, HPA031186 Enhanced Uncertain Plasma membrane Renal cancer:2.28e-4 (unfavourable), Urothelial cancer:3.21e-4 (favourable) Group enriched Tissue enhanced colon: 736.0;duodenum: 526.9;rectum: 640.3;small intestine: 493.5 gallbladder: 138.8 Cell line enhanced CACO-2: 1.0;RT4: 2.2;SH-SY5Y: 1.0 +LRRC34 MGC27085 ENSG00000171757 Leucine rich repeat containing 34 3 169793428-169812986 Predicted intracellular proteins Evidence at protein level HPA035747 Approved Approved Cell Junctions
Microtubules
Cytokinetic bridge Mixed Group enriched 8 fallopian tube: 12.2;testis: 26.8 cerebral cortex: 2.2 Cell line enhanced HEL: 7.6;HL-60: 7.2;NTERA-2: 8.7 +PAH PH ENSG00000171759 Phenylalanine hydroxylase 12 102836885-102958410 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA028407, HPA031642 Enhanced Approved Endoplasmic reticulum
Vesicles Liver cancer:4.30e-4 (favourable) Tissue enriched Tissue enhanced kidney: 504.6;liver: 722.4 gallbladder: 125.9 Cell line enriched 26 Hep G2: 161.3 +SPATA5L1 FLJ12286, MGC5347 ENSG00000171763 Spermatogenesis associated 5 like 1 15 45402331-45421419 Predicted intracellular proteins Evidence at protein level HPA043679 Uncertain Approved Nucleus
Nucleoli Prostate cancer:7.88e-4 (unfavourable) Expressed in all Mixed thyroid gland: 8.9 Expressed in all +GATM AGAT ENSG00000171766 Glycine amidinotransferase 15 45361124-45402327 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026077 Enhanced Supported Mitochondria Renal cancer:1.38e-4 (favourable) Expressed in all Group enriched 6 kidney: 1904.2;liver: 1291.1;pancreas: 573.9 ovary: 195.7 Cell line enhanced RH-30: 190.4;U-266/70: 92.4;U-266/84: 115.1 +SYCE1 bA108K14.6, C10orf94, CT76 ENSG00000171772 Synaptonemal complex central element protein 1 10 133553901-133569835 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040208 Enhanced Uncertain Nucleoplasm
Cytosol Not detected Tissue enriched 6 testis: 81.8 placenta: 13.3 Group enriched 10 K-562: 16.5;U-2 OS: 16.2 +NXNL1 RDCVF, TXNL6 ENSG00000171773 Nucleoredoxin-like 1 19 17455425-17460954 Predicted intracellular proteins Evidence at protein level HPA042010 Approved Not detected Tissue enhanced adipose tissue: 2.0 skin: 1.0 Not detected +RASGRP4 ENSG00000171777 RAS guanyl releasing protein 4 19 38409051-38426305 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Tissue enhanced Tissue enhanced bone marrow: 13.1 appendix: 8.7 Group enriched 6 HEL: 21.5;HMC-1: 20.1;U-937: 4.8 +NHLH1 bHLHa35, HEN1, NSCL, NSCL1 ENSG00000171786 Nescient helix-loop-helix 1 1 160367067-160372848 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA017943, CAB033854 Uncertain Approved Golgi apparatus Group enriched Not detected skin: 0.8 Cell line enriched 12 SCLC-21H: 30.9 +SLFNL1 FLJ23878 ENSG00000171790 Schlafen like 1 1 41015597-41023237 Predicted intracellular proteins Evidence at protein level HPA054956 Approved Cytosol Not detected Tissue enriched 16 testis: 47.8 lung: 3.0 Cell line enhanced CACO-2: 4.4 +BCL2 Bcl-2, PPP1R50 ENSG00000171791 BCL2, apoptosis regulator 18 63123346-63320128 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000003, HPA055295 Enhanced Supported Nucleoplasm
Nuclear membrane Renal cancer:1.29e-8 (favourable), Cervical cancer:5.13e-5 (favourable), Thyroid cancer:2.47e-4 (unfavourable) Expressed in all Tissue enhanced thyroid gland: 69.3 parathyroid gland: 35.3 Cell line enhanced Karpas-707: 59.5;U-266/70: 217.8 +RHNO1 C12orf32, HKMT1188, MGC13204, RHINO ENSG00000171792 RAD9-HUS1-RAD1 interacting nuclear orphan 1 12 2876258-2889523 Predicted intracellular proteins Evidence at protein level Renal cancer:5.74e-13 (unfavourable), Liver cancer:2.20e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 28.4 Expressed in all +CTPS1 CTPS ENSG00000171793 CTP synthase 1 1 40979335-41012565 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB017111, HPA051322 Enhanced Supported Actin filaments
Cytosol Expressed in all Expressed in all smooth muscle: 80.2 Expressed in all +UTF1 ENSG00000171794 Undifferentiated embryonic cell transcription factor 1 10 133230274-133231558 Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enriched Tissue enriched 11 testis: 1.4 spleen: 0.1 Group enriched 18 NTERA-2: 5.7;RPMI-8226: 1.4 +KNDC1 bB439H18.3, C10orf23, FLJ25027, KIAA1768, RASGEF2 ENSG00000171798 Kinase non-catalytic C-lobe domain containing 1 10 133160447-133226412 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039624 Uncertain Mixed Tissue enhanced cerebral cortex: 19.4;fallopian tube: 10.4 adrenal gland: 6.4 Cell line enhanced AN3-CA: 1.5;EFO-21: 1.1;NTERA-2: 1.4;RPMI-8226: 1.4 +WDR87 NYD-SP11 ENSG00000171804 WD repeat domain 87 19 37884823-37906677 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 203 testis: 30.5 thyroid gland: 0.1 Not detected +METTL18 AsTP2, C1orf156, HPM1, MGC9084 ENSG00000171806 Methyltransferase like 18 1 169792529-169794966 Predicted intracellular proteins Evidence at protein level HPA035314 Approved Approved Nucleoplasm
Cytosol Liver cancer:1.01e-4 (unfavourable), Urothelial cancer:3.28e-4 (favourable), Renal cancer:4.06e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 44.5 lymph node: 15.3 Expressed in all +CFAP46 bA288G11.4, bA288G11.5, bB137A17.2, bB137A17.3, C10orf123, C10orf124, C10orf92, C10orf93, DKFZp434A1721, FLJ25954, TTC40 ENSG00000171811 Cilia and flagella associated protein 46 10 132808392-132942823 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA037786, HPA038034, HPA038867, HPA038868 Uncertain Mixed Tissue enhanced fallopian tube: 11.7;skeletal muscle: 11.4;testis: 23.8 thyroid gland: 4.5 Cell line enhanced HAP1: 1.0;SH-SY5Y: 1.0 +COL8A2 FECD, FECD1, PPCD, PPCD2 ENSG00000171812 Collagen type VIII alpha 2 chain 1 36095236-36125220 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049788 Uncertain Uncertain Golgi apparatus Renal cancer:9.35e-5 (unfavourable), Ovarian cancer:7.26e-4 (unfavourable), Head and neck cancer:9.44e-4 (favourable) Expressed in all Mixed placenta: 18.2 Cell line enhanced BJ: 4.9;fHDF/TERT166: 3.3;HHSteC: 11.8 +PWWP2B bA432J24.1, FLJ46823, PWWP2 ENSG00000171813 PWWP domain containing 2B 10 132397168-132417863 Predicted intracellular proteins Evidence at protein level HPA038056, HPA038502 Enhanced Nucleoplasm Renal cancer:5.75e-4 (favourable) Expressed in all Mixed spleen: 16.4 Cell line enhanced BEWO: 53.5;MCF7: 33.4 +PCDHB1 PCDH-BETA1 ENSG00000171815 Protocadherin beta 1 5 141051135-141059344 Predicted membrane proteins Evidence at protein level HPA053921 Uncertain Not detected Not detected fallopian tube,testis: 0.7 Not detected +ZNF540 DKFZp547B0714 ENSG00000171817 Zinc finger protein 540 19 37551406-37614097 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003444 Supported Supported Nucleoplasm
Vesicles
Cytosol Mixed Mixed thyroid gland: 13.3 Mixed +ANGPTL7 AngX, CDT6 ENSG00000171819 Angiopoietin like 7 1 11189341-11195981 Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enhanced seminal vesicle: 9.3 gallbladder: 5.8 Cell line enriched 434 SCLC-21H: 48.4 +FBXL14 Fbl14, MGC40195 ENSG00000171823 F-box and leucine rich repeat protein 14 12 1565993-1594165 Predicted intracellular proteins Evidence at protein level HPA053889 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:9.04e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 15.2 Mixed +EXOSC10 p2, p3, p4, PM-Scl, PM/Scl-100, PMSCL2, RRP6, Rrp6p ENSG00000171824 Exosome component 10 1 11066618-11099881 Predicted intracellular proteins Evidence at protein level HPA028470, HPA028484, CAB037141 Enhanced Supported Nucleus
Nucleoli
Cytosol Liver cancer:2.49e-6 (unfavourable), Thyroid cancer:5.27e-4 (favourable) Expressed in all Expressed in all endometrium: 46.8 Expressed in all +ZNF570 FLJ30791 ENSG00000171827 Zinc finger protein 570 19 37467585-37488652 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at transcript level HPA028881 Uncertain Approved Nucleoplasm Renal cancer:4.06e-5 (favourable) Expressed in all Mixed testis: 10.7 Mixed +NINJ2 ENSG00000171840 Ninjurin 2 12 564296-663779 Predicted membrane proteins Evidence at protein level HPA058980 Approved Endoplasmic reticulum Head and neck cancer:5.31e-4 (favourable) Expressed in all Tissue enhanced lung: 55.6 bone marrow: 23.9 Cell line enhanced HEL: 137.2;MOLT-4: 210.8 +MLLT3 AF-9, AF9, YEATS3 ENSG00000171843 MLLT3, super elongation complex subunit 9 20341665-20622543 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001824 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.84e-4 (favourable) Expressed in all Mixed thyroid gland: 40.6 Cell line enhanced HEL: 229.3 +FAM90A1 FLJ10408 ENSG00000171847 Family with sequence similarity 90 member A1 12 8221260-8227618 Predicted intracellular proteins Evidence at protein level Endometrial cancer:3.92e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 11.6 ovary: 5.3 Cell line enhanced BEWO: 4.7;HDLM-2: 7.1;NTERA-2: 17.6 +RRM2 ENSG00000171848 Ribonucleotide reductase regulatory subunit M2 2 10122328-10131419 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA056994 Enhanced Supported Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.39e-5 (unfavourable), Pancreatic cancer:1.62e-4 (unfavourable) Expressed in all Mixed bone marrow: 47.5 Mixed +TRAPPC12 CGI-87, TTC-15, TTC15 ENSG00000171853 Trafficking protein particle complex 12 2 3379675-3485094 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034799 Uncertain Breast cancer:1.80e-5 (favourable), Renal cancer:2.44e-4 (unfavourable), Pancreatic cancer:9.15e-4 (favourable) Expressed in all Expressed in all testis: 48.7 Expressed in all +IFNB1 IFB, IFF, IFNB ENSG00000171855 Interferon beta 1 9 21077105-21077963 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB009386 Uncertain Not detected Not detected bone marrow: 0.3 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 1.1 +RPS21 S21 ENSG00000171858 Ribosomal protein S21 20 62387116-62388520 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003371 Approved Enhanced Endoplasmic reticulum
Cytosol Liver cancer:8.46e-4 (unfavourable) Expressed in all Expressed in all ovary: 2356.2 Expressed in all +C3AR1 AZ3B, C3AR ENSG00000171860 Complement C3a receptor 1 12 8058302-8066471 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB009405 Enhanced Expressed in all Tissue enhanced appendix: 86.6 placenta: 49.5 Cell line enriched 9 HMC-1: 172.5 +MRM3 FLJ10581, HC90, RMTL1, RNMTL1 ENSG00000171861 Mitochondrial rRNA methyltransferase 3 17 782273-792509 Predicted intracellular proteins Evidence at protein level HPA022534, HPA023031, HPA023292 Enhanced Supported Mitochondria Endometrial cancer:2.81e-4 (favourable), Renal cancer:3.00e-4 (favourable) Expressed in all Expressed in all testis: 31.3 Expressed in all +PTEN BZS, MHAM, MMAC1, PTEN1, TEP1 ENSG00000171862 Phosphatase and tensin homolog 10 87863113-87971930 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004076, HPA031335 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:7.35e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 83.6 Expressed in all +RPS7 S7 ENSG00000171863 Ribosomal protein S7 2 3575205-3580919 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA056586 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:1.34e-8 (unfavourable), Liver cancer:5.27e-4 (unfavourable) Expressed in all Expressed in all ovary: 2616.2 Expressed in all +PRND dJ1068H6.4, DOPPEL, DPL, PrPLP ENSG00000171864 Prion protein 2 (dublet) 20 4721910-4728460 Predicted membrane proteins, Transporters Evidence at protein level HPA043373 Enhanced Tissue enhanced Tissue enriched 22 testis: 136.5 endometrium: 6.0 Not detected +RNASEH1 ENSG00000171865 Ribonuclease H1 2 3544793-3558616 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA043037 Uncertain Liver cancer:7.83e-6 (unfavourable) Expressed in all Expressed in all smooth muscle: 10.9 Expressed in all +PRNP AltPrP, CD230, CJD, GSS, PRIP, PRP ENSG00000171867 Prion protein 20 4686236-4701590 CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA042754, HPA043398 Enhanced Approved Nuclear membrane
Vesicles
Cytosol Liver cancer:7.41e-5 (unfavourable), Glioma:1.99e-4 (unfavourable), Colorectal cancer:2.96e-4 (unfavourable), Endometrial cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 619.4 Cell line enhanced WM-115: 985.1 +KLF17 FLJ40160, Zfp393, ZNF393 ENSG00000171872 Kruppel like factor 17 1 44118850-44135140 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024629 Enhanced Tissue enriched Tissue enhanced testis: 8.1 smooth muscle: 1.7 Cell line enhanced BJ hTERT+ SV40 Large T+: 1.4;BJ hTERT+ SV40 Large T+ RasG12V: 1.2;HBF TERT88: 1.5;U-138 MG: 2.6 +ADRA1D ADRA1, ADRA1A, ADRA1R ENSG00000171873 Adrenoceptor alpha 1D 20 4220631-4249074 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA038789 Uncertain Mixed Tissue enhanced cervix, uterine: 4.3;prostate: 4.5 seminal vesicle: 2.6 Cell line enhanced BJ: 6.7;CAPAN-2: 3.1;fHDF/TERT166: 3.7 +FRMD5 MGC14161 ENSG00000171877 FERM domain containing 5 15 43870761-44195252 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011746, HPA013961 Uncertain Golgi apparatus
Centrosome Pancreatic cancer:5.89e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 20.4;heart muscle: 29.4 adrenal gland: 7.2 Cell line enhanced WM-115: 59.3 +AQP4 MIWC ENSG00000171885 Aquaporin 4 18 26852038-26865818 Predicted membrane proteins, Transporters Evidence at protein level CAB005079, HPA014784, CAB058689 Enhanced Supported Supported Plasma membrane
Cell Junctions Tissue enriched Group enriched 16 cerebral cortex: 630.0;lung: 171.9 thyroid gland: 24.4 Cell line enhanced AF22: 2.4;RPTEC TERT1: 1.0 +CYP4F11 ENSG00000171903 Cytochrome P450 family 4 subfamily F member 11 19 15912367-15934867 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017265, CAB033648, HPA058960 Enhanced Breast cancer:4.05e-4 (favourable), Pancreatic cancer:9.28e-4 (unfavourable) Mixed Tissue enhanced gallbladder: 29.5;liver: 32.7;small intestine: 26.3 epididymis: 20.0 Cell line enhanced A-431: 11.4;CAPAN-2: 44.2;EFO-21: 17.4;Hep G2: 17.0;RT4: 12.1 +TLN2 ILWEQ, KIAA0320 ENSG00000171914 Talin 2 15 62390526-62844631 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017194, HPA051828, HPA054787 Enhanced Supported Focal adhesion sites
Cytosol Renal cancer:1.81e-6 (favourable), Breast cancer:6.53e-4 (favourable), Stomach cancer:7.74e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 41.2;kidney: 41.1 thyroid gland: 21.7 Mixed +LGALS9C ENSG00000171916 Galectin 9C 17 18476737-18494945 Predicted intracellular proteins Evidence at protein level HPA046876, HPA047218 Approved Approved Cytosol Mixed Tissue enhanced gallbladder: 4.9;rectum: 5.0;stomach: 10.0 colon: 2.7 Not detected +TVP23B CGI-148, FAM18B, FAM18B1, YDR084C ENSG00000171928 Trans-golgi network vesicle protein 23 homolog B 17 18780995-18806714 Predicted membrane proteins Evidence at protein level HPA019585, HPA065603 Uncertain Approved Golgi apparatus Expressed in all Expressed in all thyroid gland: 78.5 Expressed in all +FBXW10 C17orf1, C17orf1A, Fbw10, HREP, SM2SH2 ENSG00000171931 F-box and WD repeat domain containing 10 17 18744024-18779349 Predicted intracellular proteins Evidence at transcript level HPA047457 Approved Nucleoplasm Not detected Tissue enriched 20 testis: 18.3 epididymis: 0.9 Cell line enhanced A549: 2.0;CAPAN-2: 1.0;HaCaT: 1.4 +OR10H3 ENSG00000171936 Olfactory receptor family 10 subfamily H member 3 19 15741393-15742343 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF217 ZABC1 ENSG00000171940 Zinc finger protein 217 20 53567065-53609907 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051857 Approved Enhanced Nuclear speckles Expressed in all Mixed testis: 41.2 Expressed in all +OR10H2 ENSG00000171942 Olfactory receptor family 10 subfamily H member 2 19 15728020-15729060 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +SRGAP2C SRGAP2P1 ENSG00000171943 SLIT-ROBO Rho GTPase activating protein 2C 1 121184810-121392822 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced parathyroid gland: 34.2 skin: 18.1 Cell line enhanced WM-115: 78.0 +OR52A5 ENSG00000171944 Olfactory receptor family 52 subfamily A member 5 11 5131692-5132642 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected bone marrow: 0.1 Not detected +SCG2 CHGC, SgII, SN ENSG00000171951 Secretogranin II 2 223596940-223602503 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA011893, HPA075062 Enhanced Supported Renal cancer:7.01e-10 (unfavourable), Pancreatic cancer:5.58e-4 (favourable) Group enriched Group enriched 8 adrenal gland: 446.7;cerebral cortex: 232.0 duodenum: 45.1 Cell line enhanced ASC TERT1: 35.0;HSkMC: 31.4;SCLC-21H: 52.8;SH-SY5Y: 20.7;WM-115: 32.8 +ATPAF2 ATP12, Atp12p, LP3663, MGC29736 ENSG00000171953 ATP synthase mitochondrial F1 complex assembly factor 2 17 17977409-18039209 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023329, HPA059422 Supported Enhanced Cytosol Renal cancer:6.00e-5 (favourable), Endometrial cancer:4.95e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 23.5 Expressed in all +CYP4F22 FLJ39501 ENSG00000171954 Cytochrome P450 family 4 subfamily F member 22 19 15508493-15552317 Disease related genes, Predicted membrane proteins Evidence at protein level HPA058960 Uncertain Group enriched Tissue enhanced esophagus: 14.0;skin: 34.3 seminal vesicle: 9.1 Cell line enhanced MCF7: 1.3 +FOXB1 FKH5, HFKH-5 ENSG00000171956 Forkhead box B1 15 60004222-60061730 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA073369 Approved Nucleoplasm
Mitochondria Tissue enhanced Not detected testis: 0.7 Cell line enhanced AF22: 6.3;HDLM-2: 13.5;HEK 293: 9.8 +PPIH CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP ENSG00000171960 Peptidylprolyl isomerase H 1 42658425-42676758 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059019 Approved Renal cancer:1.78e-9 (unfavourable), Liver cancer:1.55e-5 (unfavourable) Expressed in all Expressed in all testis: 60.1 Expressed in all +DRC3 CFAP134, DKFZP586M1120, LRRC48 ENSG00000171962 Dynein regulatory complex subunit 3 17 17972813-18016889 Predicted intracellular proteins Evidence at transcript level HPA036040, HPA036041 Approved Endometrial cancer:4.05e-5 (favourable), Breast cancer:1.51e-4 (favourable) Mixed Tissue enhanced fallopian tube: 99.2 testis: 21.8 Mixed +ZNF57 ZNF424 ENSG00000171970 Zinc finger protein 57 19 2900898-2918476 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA061915 Approved Nucleoli Renal cancer:4.11e-9 (favourable), Lung cancer:6.26e-4 (favourable), Pancreatic cancer:7.72e-4 (favourable) Expressed in all Tissue enhanced testis: 47.3 skin: 11.5 Mixed +C20orf196 FLJ25067 ENSG00000171984 Chromosome 20 open reading frame 196 20 5750393-5863912 Predicted intracellular proteins Evidence at transcript level HPA040749 Approved Approved Endoplasmic reticulum
Golgi apparatus
Vesicles Urothelial cancer:4.05e-5 (favourable) Expressed in all Mixed lymph node: 18.6 Expressed in all +C11orf40 NOV1 ENSG00000171987 Chromosome 11 open reading frame 40 11 4571423-4577820 Predicted intracellular proteins Evidence at transcript level Not detected Not detected epididymis: 0.2 Not detected +JMJD1C DKFZp761F0118, FLJ14374, KDM3C, KIAA1380, TRIP8 ENSG00000171988 Jumonji domain containing 1C 10 63167221-63521850 Predicted intracellular proteins Evidence at protein level HPA056175, HPA066195 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 55.9 Expressed in all +LDHAL6B LDH6B, LDHAL6, LDHL ENSG00000171989 Lactate dehydrogenase A like 6B 15 59206823-59208515 Enzymes, Predicted intracellular proteins Evidence at protein level HPA053962 Enhanced Not detected Tissue enriched 166 testis: 76.5 gallbladder: 0.4 Not detected +SYNPO KIAA1029 ENSG00000171992 Synaptopodin 5 150601080-150659220 Predicted intracellular proteins Evidence at protein level CAB033265, HPA034631, CAB037325, HPA071347 Enhanced Approved Nucleoplasm
Actin filaments
Cytosol Renal cancer:1.53e-6 (unfavourable) Expressed in all Tissue enhanced skeletal muscle: 446.6 heart muscle: 226.3 Cell line enhanced BEWO: 85.1;TIME: 144.5;U-87 MG: 148.8 +ZNF556 FLJ11637 ENSG00000172000 Zinc finger protein 556 19 2867335-2883445 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA060593 Approved Nucleus Mixed Tissue enhanced fallopian tube: 3.3;ovary: 6.5 testis: 1.3 Cell line enhanced Hep G2: 9.1;RH-30: 18.6 +MAL ENSG00000172005 Mal, T-cell differentiation protein 2 95025677-95053996 Predicted membrane proteins Evidence at protein level HPA065691 Approved Golgi apparatus
Centrosome Renal cancer:3.96e-9 (favourable), Endometrial cancer:5.18e-6 (unfavourable) Mixed Tissue enriched 8 esophagus: 2449.8 tonsil: 315.5 Group enriched 6 HDLM-2: 467.4;MOLT-4: 571.7;RPTEC TERT1: 1845.6 +ZNF554 FLJ34817 ENSG00000172006 Zinc finger protein 554 19 2819874-2835773 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060247, HPA063358 Uncertain Supported Nucleoplasm
Nucleoli Renal cancer:1.99e-5 (favourable), Pancreatic cancer:4.69e-4 (favourable), Urothelial cancer:5.00e-4 (favourable), Lung cancer:9.31e-4 (favourable) Expressed in all Mixed cerebral cortex: 7.5 Mixed +RAB33B DKFZP434G099 ENSG00000172007 RAB33B, member RAS oncogene family 4 139453232-139476609 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA048367 Uncertain Urothelial cancer:9.19e-4 (favourable) Expressed in all Expressed in all endometrium: 13.0 Expressed in all +THOP1 ENSG00000172009 Thimet oligopeptidase 1 19 2785460-2815807 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB025497, HPA035262 Uncertain Supported Cytosol Endometrial cancer:2.35e-4 (favourable), Stomach cancer:5.90e-4 (favourable) Expressed in all Expressed in all testis: 36.1 Mixed +ANKRD20A4 ENSG00000172014 Ankyrin repeat domain 20 family member A4 9 64369394-64413142 Predicted intracellular proteins Evidence at transcript level HPA043239, HPA047112, HPA047167, HPA047766, HPA051753 Uncertain Not detected Mixed testis: 1.2 Cell line enhanced HDLM-2: 1.5 +REG3A HIP, PAP, PAP1, PBCGF, REG-III, REG3 ENSG00000172016 Regenerating family member 3 alpha 2 79157003-79159753 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA047894, HPA048334, HPA060705 Supported Approved Cytosol Tissue enhanced Group enriched 56 duodenum: 5635.7;small intestine: 8081.8 stomach: 122.0 Cell line enhanced BEWO: 18.5;EFO-21: 17.0;HDLM-2: 16.3;RPMI-8226: 17.5;SH-SY5Y: 16.7;U-2 OS: 30.9 +GAP43 B-50, PP46 ENSG00000172020 Growth associated protein 43 3 115623324-115721490 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004417, HPA013392, HPA015600 Enhanced Enhanced Plasma membrane Tissue enriched Tissue enriched 38 cerebral cortex: 345.9 appendix: 9.1 Group enriched 6 AF22: 34.3;NTERA-2: 74.0;SCLC-21H: 55.5;SH-SY5Y: 37.6;U-87 MG: 16.1 +REG1B PSPS2, REGH, REGI-BETA, REGL ENSG00000172023 Regenerating family member 1 beta 2 79085030-79088019 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045549, HPA045579 Supported Tissue enhanced Tissue enhanced duodenum: 734.2;small intestine: 435.2 pancreas: 181.6 Cell line enhanced EFO-21: 6.0;HDLM-2: 3.9;U-2 OS: 15.6;U-251 MG: 3.2 +EPHX4 ABHD7, EPHXRP, FLJ90341 ENSG00000172031 Epoxide hydrolase 4 1 92029982-92063536 Predicted intracellular proteins Evidence at protein level HPA035067 Uncertain Approved Vesicles Pancreatic cancer:2.00e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 14.6 thyroid gland: 3.0 Cell line enhanced A-431: 13.4;CAPAN-2: 11.4;EFO-21: 24.3;RPTEC TERT1: 27.3 +LAMB2 LAMS, NPHS5 ENSG00000172037 Laminin subunit beta 2 3 49121114-49133118 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000053, HPA001895, HPA050033, CAB078160 Supported Approved Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 207.4 Cell line enhanced fHDF/TERT166: 231.7 +USP19 KIAA0891, ZMYND9 ENSG00000172046 Ubiquitin specific peptidase 19 3 49108046-49120938 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:7.05e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 45.7 Expressed in all +QARS ENSG00000172053 Glutaminyl-tRNA synthetase 3 49095932-49105135 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036986, HPA036987 Enhanced Enhanced Cytosol Renal cancer:5.60e-6 (favourable), Breast cancer:1.43e-4 (favourable) Expressed in all Expressed in all rectum: 117.0 Expressed in all +ORMDL3 ENSG00000172057 ORMDL sphingolipid biosynthesis regulator 3 17 39921041-39927601 Disease related genes, Predicted membrane proteins Evidence at protein level HPA065643 Supported Endoplasmic reticulum Urothelial cancer:5.18e-4 (favourable), Lung cancer:9.29e-4 (favourable) Expressed in all Expressed in all adipose tissue: 164.7 Expressed in all +SERF1A 4F5, FAM2A, H4F5, SERF1, SMAM1 ENSG00000172058 Small EDRK-rich factor 1A 5 70900665-70918530 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA075271 Approved Nuclear bodies Not detected Mixed cerebral cortex: 9.1 Mixed +KLF11 MODY7, TIEG2, Tieg3 ENSG00000172059 Kruppel like factor 11 2 10042849-10054836 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058276 Approved Nucleoplasm
Focal adhesion sites
Cytosol Expressed in all Expressed in all testis: 56.4 Mixed +LRRC15 LIB ENSG00000172061 Leucine rich repeat containing 15 3 194355247-194369743 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA035503 Uncertain Approved Vesicles
Plasma membrane Tissue enhanced Mixed cervix, uterine: 4.7 Group enriched 8 fHDF/TERT166: 93.4;U-138 MG: 22.2;U-87 MG: 61.4 +SMN1 BCD541, GEMIN1, SMA, SMA@, SMA1, SMA2, SMA3, SMNT, TDRD16A ENSG00000172062 Survival of motor neuron 1, telomeric 5 70925030-70953942 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045271, CAB069888 Enhanced Renal cancer:6.62e-13 (unfavourable) Expressed in all Mixed lymph node: 17.0 Cell line enhanced MOLT-4: 95.9;T-47d: 82.9;WM-115: 116.4 +EIF2AK3 PEK, PERK ENSG00000172071 Eukaryotic translation initiation factor 2 alpha kinase 3 2 88556741-88627576 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB009204, HPA015737 Enhanced Expressed in all Mixed parathyroid gland: 37.3 Expressed in all +TEX37 C2orf51, FLJ25369, TSC21 ENSG00000172073 Testis expressed 37 2 88524651-88529584 Predicted intracellular proteins Evidence at protein level HPA043987 Enhanced Tissue enriched Tissue enriched 515 testis: 82.4 placenta: 0.1 Cell line enriched 40 BEWO: 48.5 +MOB3A MOB-LAK, MOB1C, MOBKL2A, moblak ENSG00000172081 MOB kinase activator 3A 19 2071038-2096673 Predicted intracellular proteins Evidence at protein level HPA057744 Uncertain Intermediate filaments
Cytosol Endometrial cancer:1.33e-6 (favourable), Renal cancer:1.93e-4 (unfavourable) Expressed in all Expressed in all lymph node: 85.3 Expressed in all +KRCC1 FLJ22333 ENSG00000172086 Lysine rich coiled-coil 1 2 88027205-88055729 Predicted intracellular proteins Evidence at protein level HPA045618, HPA052666 Approved Approved Nucleoli
Cytosol Expressed in all Expressed in all parathyroid gland: 59.4 Expressed in all +NME6 IPIA-ALPHA, NM23-H6 ENSG00000172113 NME/NM23 nucleoside diphosphate kinase 6 3 48293264-48301685 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017909 Approved Approved Vesicles Liver cancer:2.17e-7 (unfavourable), Renal cancer:3.18e-5 (favourable) Expressed in all Expressed in all fallopian tube: 27.7 Expressed in all +CYCS CYC, HCS ENSG00000172115 Cytochrome c, somatic 7 25120091-25125361 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004222, CAB005126, CAB018597 Enhanced Supported Mitochondria Renal cancer:1.30e-5 (favourable), Head and neck cancer:2.81e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 309.2 Expressed in all +CD8B CD8B1 ENSG00000172116 CD8b molecule 2 86815339-86861924 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004353, HPA029164 Enhanced Supported Plasma membrane Endometrial cancer:7.88e-7 (favourable), Renal cancer:7.11e-6 (unfavourable) Mixed Tissue enhanced cervix, uterine: 60.8;lymph node: 39.6 parathyroid gland: 22.7 Cell line enriched 50 RPMI-8226: 837.8 +SLFN12 FLJ10260 ENSG00000172123 Schlafen family member 12 17 35411060-35433283 Predicted intracellular proteins Evidence at protein level HPA022523 Uncertain Renal cancer:4.14e-5 (unfavourable) Mixed Mixed spleen: 13.2 Mixed +CALB2 CAL2 ENSG00000172137 Calbindin 2 16 71358713-71390438 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB000106, HPA007305, HPA007306 Enhanced Supported Enhanced Cytosol Colorectal cancer:5.78e-5 (unfavourable) Mixed Tissue enhanced adipose tissue: 54.6;testis: 24.9 adrenal gland: 12.7 Cell line enhanced HEL: 57.0;HMC-1: 116.3;U-2 OS: 39.2 +SLC9C1 NHE, SLC9A10 ENSG00000172139 Solute carrier family 9 member C1 3 112140887-112294258 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Group enriched 10 skin: 2.9;testis: 14.1 thyroid gland: 0.8 Not detected +OR1A1 OR17-7 ENSG00000172146 Olfactory receptor family 1 subfamily A member 1 17 3215621-3216550 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR1A2 OR17-6 ENSG00000172150 Olfactory receptor family 1 subfamily A member 2 17 3197519-3198448 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR8I2 ENSG00000172154 Olfactory receptor family 8 subfamily I member 2 11 56093308-56094240 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +LCE1D LEP4 ENSG00000172155 Late cornified envelope 1D 1 152796751-152798181 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 306 skin: 101.7 skeletal muscle: 0.3 Not detected +CCL11 eotaxin, MGC22554, SCYA11 ENSG00000172156 C-C motif chemokine ligand 11 17 34285668-34288334 Cancer-related genes, Predicted secreted proteins Evidence at protein level Head and neck cancer:1.99e-4 (favourable), Colorectal cancer:8.70e-4 (favourable) Mixed Tissue enhanced appendix: 39.3;small intestine: 37.3 duodenum: 30.8 Cell line enriched 18 BJ hTERT+: 7.2 +FRMD3 EPB41L4O, MGC20553 ENSG00000172159 FERM domain containing 3 9 83242990-83538546 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017285 Approved Approved Nucleoplasm
Golgi apparatus
Plasma membrane Thyroid cancer:1.79e-4 (favourable), Renal cancer:7.24e-4 (favourable) Tissue enhanced Tissue enhanced heart muscle: 56.5 skeletal muscle: 28.5 Cell line enhanced HEL: 21.0;RPMI-8226: 54.8;SCLC-21H: 32.9 +SNTB1 59-DAP, A1B, BSYN2, SNT2, SNT2B1, TIP-43 ENSG00000172164 Syntrophin beta 1 8 120535745-120813273 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA024659 Uncertain Expressed in all Tissue enhanced adrenal gland: 73.7;thyroid gland: 100.8 liver: 45.3 Cell line enhanced Hep G2: 61.4;U-266/70: 69.2 +MTBP ENSG00000172167 MDM2 binding protein 8 120445400-120542133 Predicted intracellular proteins Evidence at protein level HPA025694, HPA050594 Uncertain Approved Nucleus Mixed Mixed testis: 9.1 Mixed +TEFM C17orf42, FLJ22729 ENSG00000172171 Transcription elongation factor, mitochondrial 17 30897336-30906820 Predicted intracellular proteins Evidence at protein level HPA023788, HPA053044 Approved Enhanced Mitochondria Melanoma:8.64e-4 (unfavourable), Liver cancer:9.20e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 5.6 Expressed in all +MRPL13 L13, L13A, L13mt, RPL13, RPML13 ENSG00000172172 Mitochondrial ribosomal protein L13 8 120380761-120445402 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA060899 Approved Breast cancer:1.37e-4 (unfavourable) Expressed in all Expressed in all kidney: 49.4 Expressed in all +MALT1 MLT, PCASP1 ENSG00000172175 MALT1 paracaspase 18 58671386-58754477 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004494, HPA048432 Enhanced Supported Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 34.0 Expressed in all +PRL ENSG00000172179 Prolactin 6 22287244-22297501 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB023353, HPA042416, HPA062017 Enhanced Uncertain Cytosol Not detected Group enriched 9 endometrium: 10.7;placenta: 27.2 testis: 2.2 Cell line enhanced Daudi: 11.1;SCLC-21H: 6.5;U-937: 2.1 +ISG20 CD25, HEM45 ENSG00000172183 Interferon stimulated exonuclease gene 20 15 88636153-88656483 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.86e-8 (unfavourable), Ovarian cancer:1.85e-5 (favourable), Glioma:3.12e-5 (unfavourable) Expressed in all Tissue enhanced lymph node: 221.4 spleen: 136.2 Cell line enhanced Daudi: 151.0;SK-MEL-30: 543.4 +OR4C11 OR4C11P ENSG00000172188 Olfactory receptor family 4 subfamily C member 11 11 55603354-55604398 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +MBOAT1 dJ434O11.1, LPEAT1, MGC44669, OACT1 ENSG00000172197 Membrane bound O-acyltransferase domain containing 1 6 20102145-20212399 Enzymes, Predicted membrane proteins Evidence at protein level HPA052996 Approved Mitochondria Pancreatic cancer:9.15e-4 (unfavourable) Expressed in all Mixed fallopian tube: 55.7 Cell line enhanced HaCaT: 55.4;HEL: 47.2 +OR8U1 ENSG00000172199 Olfactory receptor family 8 subfamily U member 1 11 56375624-56376553 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ID4 bHLHb27 ENSG00000172201 Inhibitor of DNA binding 4, HLH protein 6 19837386-19840684 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060800 Supported Nucleus Pancreatic cancer:2.49e-4 (favourable) Expressed in all Tissue enhanced thyroid gland: 626.0 fallopian tube: 128.5 Cell line enhanced AF22: 57.9;AN3-CA: 71.8;EFO-21: 163.7;HEK 293: 91.1;SCLC-21H: 185.5 +GPR22 ENSG00000172209 G protein-coupled receptor 22 7 107470018-107475659 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Group enriched 13 adrenal gland: 1.2;cerebral cortex: 4.7;cervix, uterine: 3.2;endometrium: 2.5;heart muscle: 5.4 smooth muscle: 0.2 Cell line enriched 29 SH-SY5Y: 2.9 +CXCR6 BONZO, CD186, STRL33, TYMSTR ENSG00000172215 C-X-C motif chemokine receptor 6 3 45940933-45948353 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Endometrial cancer:6.74e-6 (favourable), Renal cancer:2.42e-5 (unfavourable), Head and neck cancer:2.16e-4 (favourable), Cervical cancer:4.92e-4 (favourable) Mixed Mixed lymph node: 17.3 Group enriched 6 BEWO: 2.8;CAPAN-2: 9.8 +CEBPB C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5 ENSG00000172216 CCAAT/enhancer binding protein beta 20 50190734-50192689 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004213, HPA061355, HPA062267 Supported Enhanced Nucleoplasm Renal cancer:2.44e-12 (unfavourable) Expressed in all Expressed in all adrenal gland: 112.4 Expressed in all +AZU1 AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC ENSG00000172232 Azurocidin 1 19 825097-832018 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA055851 Enhanced Mixed Tissue enriched 525 bone marrow: 1311.2 skin: 2.4 Cell line enriched 6 THP-1: 722.4 +TPSAB1 TPS1, TPS2, TPSB1 ENSG00000172236 Tryptase alpha/beta 1 16 1240696-1242554 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016369, CAB022175, HPA049153, HPA049554 Supported Head and neck cancer:9.62e-6 (favourable) Mixed Tissue enhanced gallbladder: 211.6 lung: 158.5 Cell line enriched 163 HMC-1: 3406.5 +ATOH1 bHLHa14, HATH1, MATH-1, Math1 ENSG00000172238 Atonal bHLH transcription factor 1 4 93828753-93830964 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level Colorectal cancer:3.26e-5 (favourable) Tissue enhanced Group enriched 9 colon: 17.6;duodenum: 11.1;rectum: 19.7;small intestine: 22.4 appendix: 1.9 Not detected +PAIP1 ENSG00000172239 Poly(A) binding protein interacting protein 1 5 43526267-43557758 Predicted intracellular proteins Evidence at protein level HPA073653, HPA076187 Approved Approved Plasma membrane
Cytosol Pancreatic cancer:4.79e-4 (unfavourable) Expressed in all Expressed in all testis: 153.0 Expressed in all +CLEC7A CD369, CLECSF12, dectin-1, hDectin-1, SCARE2 ENSG00000172243 C-type lectin domain family 7 member A 12 10116777-10130258 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043244, HPA050229 Approved Nucleoplasm
Vesicles Renal cancer:1.31e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 65.6 bone marrow: 53.3 Group enriched 15 Karpas-707: 144.0;U-266/84: 116.1 +C5orf34 FLJ32363 ENSG00000172244 Chromosome 5 open reading frame 34 5 43486701-43515145 Predicted intracellular proteins Evidence at protein level HPA045386 Approved Endometrial cancer:2.65e-6 (unfavourable) Expressed in all Tissue enhanced testis: 7.7 prostate: 3.9 Mixed +C1QTNF4 CTRP4, ZACRP4 ENSG00000172247 C1q and tumor necrosis factor related protein 4 11 47589664-47594659 Predicted secreted proteins Evidence at protein level HPA041032 Approved Mixed Tissue enriched 5 cerebral cortex: 28.2 parathyroid gland: 5.2 Cell line enriched 6 REH: 10.4 +NEGR1 IGLON4, KILON, MGC46680, Ntra ENSG00000172260 Neuronal growth regulator 1 1 71395940-72282734 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA011894 Uncertain Approved Vesicles
Actin filaments
Cytosol Mixed Tissue enhanced cerebral cortex: 54.3 gallbladder: 16.9 Mixed +ZNF131 pHZ-10, ZBTB35 ENSG00000172262 Zinc finger protein 131 5 43065176-43192021 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007023, HPA027748, HPA074630 Approved Enhanced Nucleoplasm
Intermediate filaments Liver cancer:1.56e-4 (unfavourable) Expressed in all Expressed in all testis: 59.4 Expressed in all +MACROD2 C20orf133, dJ631M13.5 ENSG00000172264 MACRO domain containing 2 20 13995369-16053197 Predicted intracellular proteins Evidence at protein level HPA049076 Enhanced Supported Nucleus
Nucleoli
Centrosome Mixed Mixed lung: 16.2 Cell line enhanced EFO-21: 14.4;Karpas-707: 13.4;SCLC-21H: 12.6 +DPAGT1 ALG7, CDG-Ij, D11S366, DGPT, DPAGT, DPAGT2, GPT ENSG00000172269 Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 11 119096503-119108331 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA053878 Approved Liver cancer:2.03e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 25.5 Expressed in all +BSG CD147, EMMPRIN, OK ENSG00000172270 Basigin (Ok blood group) 19 571277-583493 Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB002427, HPA036048, HPA074870 Enhanced Approved Vesicles Renal cancer:1.95e-6 (favourable), Liver cancer:5.48e-6 (unfavourable), Endometrial cancer:2.59e-4 (favourable) Expressed in all Expressed in all heart muscle: 593.5 Expressed in all +HINFP DKFZP434F162, HiNF-P, MIZF, ZNF743 ENSG00000172273 Histone H4 transcription factor 11 119121587-119136044 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA061008 Uncertain Liver cancer:4.44e-8 (unfavourable), Thyroid cancer:5.26e-4 (favourable) Expressed in all Expressed in all testis: 11.9 Expressed in all +CDY1 CDY1A ENSG00000172288 Chromodomain Y-linked 1 Y 25622162-25624902 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 11 testis: 1.0 all non-specific tissues: 0.0 Not detected +OR10V1 ENSG00000172289 Olfactory receptor family 10 subfamily V member 1 11 59712823-59713864 G-protein coupled receptors, Predicted membrane proteins No evidence HPA060076 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +CERS6 LASS6 ENSG00000172292 Ceramide synthase 6 2 168455862-168775137 Predicted membrane proteins Evidence at protein level HPA044683, HPA063527 Approved Supported Nucleus Liver cancer:1.10e-4 (unfavourable), Endometrial cancer:7.31e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 43.5 Mixed +SPTLC3 C20orf38, FLJ11112, hLCB2b, LCB2B, SPTLC2L ENSG00000172296 Serine palmitoyltransferase long chain base subunit 3 20 13008979-13169103 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044247, HPA048079 Enhanced Approved Microtubules Renal cancer:4.51e-7 (favourable), Pancreatic cancer:6.02e-4 (unfavourable) Expressed in all Mixed thyroid gland: 40.8 Cell line enhanced RPTEC TERT1: 33.2;U-87 MG: 56.0 +COPRS C17orf79, COPR5, HSA272196, TTP1 ENSG00000172301 Coordinator of PRMT5 and differentiation stimulator 17 31851864-31859337 Predicted intracellular proteins Evidence at protein level HPA052552 Approved Supported Nucleus
Plasma membrane
Cytosol Liver cancer:3.69e-4 (unfavourable) Expressed in all Expressed in all testis: 268.0 Expressed in all +TP53RK BUD32, C20orf64, dJ101A2.2, Nori-2p, prpk ENSG00000172315 TP53 regulating kinase 20 46684365-46689779 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004688, HPA015837 Approved Liver cancer:6.27e-5 (unfavourable), Endometrial cancer:6.70e-5 (unfavourable) Expressed in all Expressed in all testis: 16.6 Expressed in all +B3GALT1 beta3Gal-T1 ENSG00000172318 Beta-1,3-galactosyltransferase 1 2 167868948-167874041 Enzymes, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 5.2;colon: 3.7;rectum: 4.0 skeletal muscle: 1.8 Cell line enriched 7 AN3-CA: 33.1 +OR5A1 OR5A1P, OST181 ENSG00000172320 Olfactory receptor family 5 subfamily A member 1 11 59443144-59444194 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.1 Not detected +CLEC12A CD371, CLL-1, DCAL-2, MICL ENSG00000172322 C-type lectin domain family 12 member A 12 9951316-9995694 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048515 Enhanced Urothelial cancer:9.33e-4 (favourable) Mixed Tissue enhanced bone marrow: 51.3 spleen: 26.6 Group enriched 7 HL-60: 17.3;U-937: 52.2 +OR5A2 ENSG00000172324 Olfactory receptor family 5 subfamily A member 2 11 59421943-59422976 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047135, HPA049575 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +BPGM ENSG00000172331 Bisphosphoglycerate mutase 7 134646808-134679813 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA016493, HPA028735 Enhanced Approved Nucleoli Renal cancer:1.54e-8 (favourable), Cervical cancer:7.95e-4 (favourable) Expressed in all Expressed in all placenta: 65.1 Expressed in all +POP7 RPP2, RPP20 ENSG00000172336 POP7 homolog, ribonuclease P/MRP subunit 7 100706053-100707495 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021007 Uncertain Supported Nucleoli
Vesicles Liver cancer:4.99e-5 (unfavourable), Renal cancer:6.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 41.1 Expressed in all +ALG14 MGC19780 ENSG00000172339 ALG14, UDP-N-acetylglucosaminyltransferase subunit 1 94974407-95072945 Disease related genes, Predicted membrane proteins Evidence at protein level HPA031829 Approved Approved Nucleus
Nucleoli Expressed in all Mixed thyroid gland: 2.9 Mixed +SUCLG2 ENSG00000172340 Succinate-CoA ligase GDP-forming beta subunit 3 67360460-67654614 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046705, HPA051998 Enhanced Supported Plasma membrane
Mitochondria Renal cancer:2.79e-10 (favourable), Colorectal cancer:1.08e-4 (favourable) Expressed in all Expressed in all colon: 168.2 Expressed in all +STARD5 MGC10327 ENSG00000172345 StAR related lipid transfer domain containing 5 15 81309053-81324183 Predicted intracellular proteins Evidence at protein level HPA040662 Approved Approved Vesicles
Cytosol Mixed Mixed skin: 9.4 Cell line enhanced HMC-1: 5.2;U-266/70: 5.5;U-937: 5.4 +CSDC2 PIPPin ENSG00000172346 Cold shock domain containing C2 22 41560763-41577741 Predicted intracellular proteins Evidence at protein level HPA003073, HPA076549 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:6.42e-4 (favourable) Mixed Tissue enhanced adrenal gland: 62.5;ovary: 72.0 heart muscle: 45.3 Cell line enriched 6 U-2 OS: 40.5 +RCAN2 DSCR1L1, ZAKI-4 ENSG00000172348 Regulator of calcineurin 2 6 46220736-46491972 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053880 Uncertain Approved Nucleoplasm
Mitochondria Renal cancer:1.12e-6 (favourable), Pancreatic cancer:2.48e-4 (favourable) Expressed in all Mixed parathyroid gland: 145.4 Group enriched 6 fHDF/TERT166: 49.1;HDLM-2: 120.1 +IL16 FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16 ENSG00000172349 Interleukin 16 15 81159575-81314058 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005247, HPA018467 Enhanced Approved Nuclear speckles
Plasma membrane
Cytosol Expressed in all Tissue enhanced lymph node: 154.4;tonsil: 124.0 spleen: 118.2 Cell line enhanced HEL: 26.3;HMC-1: 44.5;RPMI-8226: 34.9;U-266/70: 45.9;U-937: 27.4 +ABCG4 WHITE2 ENSG00000172350 ATP binding cassette subfamily G member 4 11 119149012-119162653 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA040312 Uncertain Not detected Group enriched 6 cerebral cortex: 6.6;parathyroid gland: 4.1;testis: 5.1 seminal vesicle: 0.8 Cell line enhanced AN3-CA: 1.7;HAP1: 1.0 +CDY1B ENSG00000172352 Chromodomain Y-linked 1B Y 24045229-24048019 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 40 testis: 4.0 all non-specific tissues: 0.0 Not detected +GNB2 ENSG00000172354 G protein subunit beta 2 7 100673531-100679174 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010032, HPA040736 Approved Enhanced Plasma membrane Expressed in all Expressed in all esophagus: 235.4 Expressed in all +CFAP53 CCDC11, FLJ32743 ENSG00000172361 Cilia and flagella associated protein 53 18 50227193-50266522 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040595, HPA041069, HPA066142 Enhanced Approved Midbody Renal cancer:5.85e-4 (favourable) Mixed Group enriched 12 fallopian tube: 44.6;testis: 127.0 epididymis: 6.9 Cell line enhanced hTERT-HME1: 3.5 +OR5B12 OR5B12P, OR5B16, OST743 ENSG00000172362 Olfactory receptor family 5 subfamily B member 12 11 58439120-58440173 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR5B2 OST073 ENSG00000172365 Olfactory receptor family 5 subfamily B member 2 11 58422265-58423313 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.2 Not detected +MCRIP2 C16orf14, FAM195A, MGC15416 ENSG00000172366 MAPK regulated corepressor interacting protein 2 16 636817-648474 Predicted intracellular proteins Evidence at protein level HPA060363 Uncertain Renal cancer:1.45e-5 (favourable), Urothelial cancer:7.23e-4 (favourable) Expressed in all Mixed colon: 10.8 Mixed +PDZD3 FLJ22756, IKEPP, PDZK2 ENSG00000172367 PDZ domain containing 3 11 119185457-119190223 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enhanced duodenum: 17.3;kidney: 10.8;small intestine: 21.2 rectum: 6.7 Not detected +C2CD2L KIAA0285, TMEM24 ENSG00000172375 C2CD2 like 11 119102198-119118544 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA011044 Approved Approved Nucleus
Nuclear membrane
Nucleoli
Cytosol Renal cancer:1.75e-4 (unfavourable), Endometrial cancer:4.92e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 29.6 Expressed in all +OR9I1 ENSG00000172377 Olfactory receptor family 9 subfamily I member 1 11 58118500-58119444 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ARNT2 bHLHe1, KIAA0307 ENSG00000172379 Aryl hydrocarbon receptor nuclear translocator 2 15 80404350-80597937 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001056, CAB005081 Enhanced Supported Nucleus Pancreatic cancer:1.46e-6 (favourable), Renal cancer:7.51e-4 (favourable) Expressed in all Tissue enriched 8 cerebral cortex: 153.7 testis: 18.8 Mixed +GNG12 ENSG00000172380 G protein subunit gamma 12 1 67701466-67833467 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA057790, HPA062208 Enhanced Approved Mitochondria Expressed in all Mixed duodenum: 122.4 Mixed +PRSS27 CAPH2, MPN ENSG00000172382 Protease, serine 27 16 2712418-2720551 Enzymes, Predicted secreted proteins Evidence at protein level CAB024920 Approved Tissue enhanced Tissue enriched 7 esophagus: 210.7 tonsil: 28.1 Cell line enhanced BEWO: 6.1;SK-BR-3: 18.9;T-47d: 14.0 +MYOZ2 C4orf5, CS-1 ENSG00000172399 Myozenin 2 4 119135784-119187789 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035763, HPA035764 Enhanced Approved Nucleus
Cytosol Tissue enhanced Tissue enriched 8 heart muscle: 500.2 skeletal muscle: 63.4 Cell line enhanced HSkMC: 1.6;SK-MEL-30: 4.7;U-87 MG: 6.0 +SYNPO2 MYOPODIN ENSG00000172403 Synaptopodin 2 4 118850688-119061247 Predicted intracellular proteins Evidence at protein level HPA030665, CAB037231, HPA049707, HPA068563 Enhanced Supported Vesicles
Actin filaments
Cytosol Renal cancer:5.67e-5 (unfavourable), Urothelial cancer:3.91e-4 (unfavourable) Expressed in all Tissue enhanced seminal vesicle: 421.3 smooth muscle: 342.7 Cell line enhanced fHDF/TERT166: 44.3;SH-SY5Y: 89.5 +DNAJB7 HSC3 ENSG00000172404 DnaJ heat shock protein family (Hsp40) member B7 22 40859549-40862126 Predicted intracellular proteins Evidence at transcript level HPA000534 Approved Not detected Tissue enriched 19 testis: 10.9 duodenum,small intestine: 0.5 Not detected +CLP1 hClp1, HEAB ENSG00000172409 Cleavage and polyadenylation factor I subunit 1 11 57648992-57661868 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA057770 Supported Supported Nucleoplasm Expressed in all Expressed in all bone marrow: 17.0 Expressed in all +INSL5 ENSG00000172410 Insulin like 5 1 66797741-66801256 Predicted secreted proteins Evidence at protein level HPA030100, CAB033849 Enhanced Group enriched Group enriched 228 colon: 77.7;rectum: 141.9 cerebral cortex: 0.4 Not detected +EFCAB3 FLJ25818 ENSG00000172421 EF-hand calcium binding domain 3 17 62343941-62416479 Predicted intracellular proteins Evidence at protein level HPA046862 Uncertain Not detected Tissue enriched 24 testis: 10.5 adipose tissue: 0.4 Not detected +TTC36 HBP21 ENSG00000172425 Tetratricopeptide repeat domain 36 11 118527472-118531197 Predicted intracellular proteins Evidence at protein level HPA038731 Enhanced Uncertain Nucleoplasm Liver cancer:1.81e-5 (favourable) Group enriched Tissue enhanced liver: 64.4 epididymis: 15.5 Cell line enhanced SK-BR-3: 5.3 +RSPH9 C6orf206, CILD12, FLJ30845, MRPS18AL1 ENSG00000172426 Radial spoke head 9 homolog 6 43645046-43672599 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031703 Enhanced Mixed Group enriched 6 fallopian tube: 13.4;testis: 12.2 lung: 2.0 Cell line enhanced U-87 MG: 2.1 +COPS9 CSNAP, MYEOV2 ENSG00000172428 COP9 signalosome subunit 9 2 240126563-240136807 Predicted intracellular proteins Evidence at protein level HPA044845 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 192.2 Expressed in all +GTPBP2 ENSG00000172432 GTP binding protein 2 6 43605316-43629162 Predicted intracellular proteins Evidence at protein level HPA031418, HPA031419 Approved Enhanced Vesicles Renal cancer:1.44e-15 (unfavourable), Liver cancer:1.08e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 47.4 Expressed in all +FGGY FLJ10986 ENSG00000172456 FGGY carbohydrate kinase domain containing 1 59296638-59810647 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA054971 Approved Nucleoplasm
Nuclear bodies Expressed in all Expressed in all epididymis: 44.3 Cell line enhanced HDLM-2: 39.7 +OR9G4 ENSG00000172457 Olfactory receptor family 9 subfamily G member 4 11 56742827-56743811 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +IL17D FLJ30846, IL-17D, IL-22, IL-27, IL27 ENSG00000172458 Interleukin 17D 13 20702127-20723098 Predicted secreted proteins Evidence at protein level Group enriched Group enriched 7 cerebral cortex: 100.2;skeletal muscle: 45.9 ovary: 10.2 Mixed +FUT9 Fuc-TIX ENSG00000172461 Fucosyltransferase 9 6 96015984-96215612 Predicted membrane proteins Evidence at protein level HPA070923 Approved Nucleoplasm
Microtubules
Cytokinetic bridge
Cytosol Tissue enhanced Group enriched 12 cerebral cortex: 28.1;stomach: 22.4 duodenum: 2.0 Cell line enhanced MCF7: 2.2;RT4: 5.1;SCLC-21H: 7.5;SK-BR-3: 2.7 +OR5AP2 ENSG00000172464 Olfactory receptor family 5 subfamily AP member 2 11 56641466-56642471 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +TCEAL1 p21, pp21, SIIR, WEX9 ENSG00000172465 Transcription elongation factor A like 1 X 103628704-103630953 Predicted intracellular proteins Evidence at protein level HPA057345, HPA060384 Enhanced Nucleoplasm Expressed in all Expressed in all ovary: 146.5 Mixed +ZNF24 KOX17, Zfp191, ZNF191, ZSCAN3 ENSG00000172466 Zinc finger protein 24 18 35332212-35345482 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024062, CAB025642 Supported Supported Nucleus Renal cancer:1.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.6 Expressed in all +HSFY1 HSF2L, HSFY ENSG00000172468 Heat shock transcription factor, Y-linked 1 Y 18546671-18588963 Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Tissue enriched 93 testis: 24.8 epididymis,kidney,skin: 0.2 Not detected +MANEA FLJ12838, mandaselin ENSG00000172469 Mannosidase endo-alpha 6 95577543-95609457 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011046, HPA011069 Enhanced Supported Golgi apparatus Colorectal cancer:3.04e-4 (favourable) Expressed in all Mixed thyroid gland: 19.4 Expressed in all +RAB40A Rar-2, RAR2A ENSG00000172476 RAB40A, member RAS oncogene family X 103499130-103519489 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced epididymis: 9.8;esophagus: 7.8 prostate,testis: 5.9 Cell line enhanced AF22: 3.3;NTERA-2: 3.7 +C2orf54 FLJ22671 ENSG00000172478 Chromosome 2 open reading frame 54 2 240886048-240896889 Predicted intracellular proteins Evidence at protein level HPA052722 Approved Nucleoplasm
Golgi apparatus Endometrial cancer:2.77e-4 (unfavourable) Mixed Tissue enhanced esophagus: 112.1;skin: 51.5 tonsil: 25.5 Group enriched 7 CACO-2: 49.6;HaCaT: 39.3;SK-BR-3: 116.4 +AGXT AGT, AGT1, AGXT1, PH1, SPAT, SPT ENSG00000172482 Alanine-glyoxylate aminotransferase 2 240868479-240880502 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035370, HPA035371 Enhanced Supported Vesicles Liver cancer:5.92e-5 (favourable) Tissue enriched Tissue enriched 58 liver: 611.6 kidney: 10.4 Cell line enhanced Hep G2: 5.6;SK-BR-3: 1.1 +OR8J1 ENSG00000172487 Olfactory receptor family 8 subfamily J member 1 11 56360215-56361288 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR5T3 OR5T3Q ENSG00000172489 Olfactory receptor family 5 subfamily T member 3 11 56252200-56253222 G-protein coupled receptors, Predicted membrane proteins No evidence HPA044986 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +AFF1 AF-4, AF4, MLLT2, PBM1 ENSG00000172493 AF4/FMR2 family member 1 4 86935002-87141054 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA069947 Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all thyroid gland: 91.6 Expressed in all +ACOT12 Cach, STARD15, THEAL ENSG00000172497 Acyl-CoA thioesterase 12 5 81330005-81394179 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA037723, HPA037724 Approved Nucleoplasm
Cytosol Liver cancer:5.30e-4 (favourable) Tissue enriched Tissue enriched 19 liver: 51.3 kidney: 2.7 Not detected +FIBP FGFIBP ENSG00000172500 FGF1 intracellular binding protein 11 65883741-65888539 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA011729 Approved Supported Nuclear speckles Liver cancer:1.74e-4 (unfavourable) Expressed in all Expressed in all testis: 78.9 Expressed in all +CARNS1 ATPGD1, KIAA1394 ENSG00000172508 Carnosine synthase 1 11 67414968-67425607 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038569 Enhanced Group enriched Group enriched 11 cerebral cortex: 37.1;skeletal muscle: 25.9 heart muscle: 2.9 Cell line enriched 10 RPMI-8226: 5.3 +OR10H5 ENSG00000172519 Olfactory receptor family 10 subfamily H member 5 19 15793951-15795082 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +BANP BEND1, DKFZp761H172, FLJ10177, FLJ20538, SMAR1, SMARBP1 ENSG00000172530 BTG3 associated nuclear protein 16 87949244-88077318 Predicted intracellular proteins Evidence at protein level HPA047164 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all testis: 14.1 Expressed in all +PPP1CA PP-1A, PP1A, PP1alpha, PPP1A ENSG00000172531 Protein phosphatase 1 catalytic subunit alpha 11 67398183-67421183 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB004545, HPA046833 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Thyroid cancer:1.17e-4 (favourable) Expressed in all Expressed in all lymph node: 166.4 Expressed in all +HCFC1 CFF, HCF-1, HCF1, HFC1, MGC70925, MRX3, PPP1R89, VCAF ENSG00000172534 Host cell factor C1 X 153947553-153971807 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018312 Supported Nucleoplasm
Mitochondria Liver cancer:4.31e-6 (unfavourable), Pancreatic cancer:9.62e-5 (favourable) Expressed in all Expressed in all bone marrow: 24.6 Expressed in all +FAM170B C10orf73, Em:AC084727.4 ENSG00000172538 Family with sequence similarity 170 member B 10 49131154-49134008 Predicted intracellular proteins Evidence at protein level HPA043899, HPA050610 Uncertain Not detected Tissue enriched 75 testis: 7.4 all non-specific tissues: 0.0 Not detected +CTSW ENSG00000172543 Cathepsin W 11 65879809-65883741 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB016345 Enhanced Endometrial cancer:8.36e-6 (favourable), Renal cancer:8.84e-6 (unfavourable), Breast cancer:3.06e-4 (favourable), Head and neck cancer:9.89e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 70.6;spleen: 60.4 lung: 36.5 Group enriched 20 HEL: 149.5;NB-4: 242.5 +NIPAL4 ICHYN ENSG00000172548 NIPA like domain containing 4 5 157460019-157474717 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA038259 Approved Urothelial cancer:6.82e-4 (favourable) Tissue enhanced Tissue enhanced skin: 41.9 esophagus: 10.2 Group enriched 10 hTCEpi: 21.3;RT4: 80.1 +MUCL1 SBEM ENSG00000172551 Mucin like 1 12 54830519-54858393 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039093 Enhanced Tissue enriched Tissue enriched 43 breast: 3798.1 salivary gland: 89.1 Cell line enhanced MCF7: 1.5;SK-BR-3: 3.5 +SNTG2 G2SYN, SYN5 ENSG00000172554 Syntrophin gamma 2 2 950868-1367613 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced spleen: 2.5;testis: 2.4 adipose tissue,endometrium: 2.0 Cell line enhanced Daudi: 1.1;HAP1: 1.8;NTERA-2: 2.1;SCLC-21H: 2.3 +FNDC9 C5orf40, MGC27121 ENSG00000172568 Fibronectin type III domain containing 9 5 157341600-157345721 Predicted membrane proteins Evidence at transcript level HPA011115, HPA017291 Approved Tissue enriched Group enriched 18 adrenal gland: 6.2;cerebral cortex: 20.7 appendix: 0.7 Not detected +PDE3A CGI-PDE ENSG00000172572 Phosphodiesterase 3A 12 20369245-20684381 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA014492 Uncertain Supported Cytosol Renal cancer:1.72e-6 (unfavourable) Expressed in all Mixed heart muscle: 35.4 Group enriched 8 AF22: 15.4;HEL: 26.9;HeLa: 53.3;HUVEC TERT2: 11.9;SH-SY5Y: 31.0;U-138 MG: 22.1 +RASGRP1 CalDAG-GEFII, RASGRP ENSG00000172575 RAS guanyl releasing protein 1 15 38488103-38565575 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA039389 Supported Plasma membrane
Cytosol Mixed Tissue enhanced cerebral cortex: 28.4;lymph node: 25.0 tonsil: 15.2 Cell line enhanced HDLM-2: 50.5;MOLT-4: 41.7 +KLHL6 FLJ00029 ENSG00000172578 Kelch like family member 6 3 183487531-183555689 Predicted intracellular proteins Evidence at protein level HPA024512 Uncertain Renal cancer:3.53e-4 (unfavourable) Mixed Tissue enhanced lymph node: 35.1;tonsil: 28.7 appendix: 16.0 Cell line enhanced Daudi: 29.8;U-266/70: 62.9;U-266/84: 32.1;U-698: 86.1 +CHCHD1 C10orf34, FLJ25854 ENSG00000172586 Coiled-coil-helix-coiled-coil-helix domain containing 1 10 73782047-73783652 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA039046 Approved Supported Nucleoplasm
Nucleoli fibrillar center
Mitochondria Urothelial cancer:5.42e-4 (favourable) Expressed in all Expressed in all epididymis: 62.7 Expressed in all +MRPL52 ENSG00000172590 Mitochondrial ribosomal protein L52 14 22829879-22835037 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA012319 Approved Approved Mitochondria Expressed in all Expressed in all appendix: 72.1 Expressed in all +SMPDL3A ASM3A, ASML3a, FLJ20177, yR36GH4.1 ENSG00000172594 Sphingomyelin phosphodiesterase acid like 3A 6 122789049-122809720 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030148 Uncertain Approved Nucleus
Nucleoli
Mitochondria Colorectal cancer:6.11e-4 (favourable) Expressed in all Expressed in all small intestine: 81.9 Mixed +RND1 ARHS, Rho6, RHOS ENSG00000172602 Rho family GTPase 1 12 48857145-48865898 Predicted intracellular proteins Evidence at protein level HPA077800 Supported Vesicles
Plasma membrane
Actin filaments Mixed Tissue enhanced cerebral cortex: 39.8;liver: 31.1 gallbladder: 23.6 Cell line enriched 6 SK-BR-3: 51.2 +RAD9A RAD9 ENSG00000172613 RAD9 checkpoint clamp component A 11 67317871-67398410 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006725, HPA048155 Enhanced Enhanced Nucleoplasm Urothelial cancer:7.52e-6 (favourable), Renal cancer:2.82e-5 (unfavourable), Cervical cancer:6.95e-4 (favourable) Expressed in all Expressed in all fallopian tube: 15.0 Mixed +EFEMP2 FBLN4, UPH1 ENSG00000172638 EGF containing fibulin like extracellular matrix protein 2 11 65866441-65873592 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023270 Approved Renal cancer:3.94e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 50.3 Cell line enhanced BJ hTERT+: 106.7;fHDF/TERT166: 149.3;LHCN-M2: 95.3 +OR10AD1 OR10AD1P ENSG00000172640 Olfactory receptor family 10 subfamily AD member 1 12 48202083-48203387 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA049913 Uncertain Not detected Not detected testis: 0.9 Not detected +AGAP5 CTGLF2, Em:AC073389.1 ENSG00000172650 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 10 73674285-73698159 Predicted intracellular proteins Evidence at transcript level HPA042490 Uncertain Not detected Mixed testis: 11.6 Expressed in all +WASHC2C Em:AC012044.3, FAM21C, KIAA0592 ENSG00000172661 WASH complex subunit 2C 10 45727200-45792961 Predicted intracellular proteins Evidence at protein level HPA047844, HPA060975, HPA061022 Supported Supported Nucleoli
Vesicles
Cytosol Liver cancer:1.35e-5 (unfavourable), Lung cancer:4.69e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 41.9 Expressed in all +TMEM134 FLJ21749 ENSG00000172663 Transmembrane protein 134 11 67461710-67469272 Predicted membrane proteins Evidence at protein level HPA043744 Approved Supported Cytosol Expressed in all Expressed in all skin: 38.5 Expressed in all +ZMAT3 FLJ12296, MGC10613, PAG608, WIG-1, WIG1 ENSG00000172667 Zinc finger matrin-type 3 3 179017223-179072279 Predicted intracellular proteins Evidence at protein level HPA027569, HPA028671, HPA054356 Enhanced Supported Nucleoplasm Expressed in all Mixed cerebral cortex: 29.0 Expressed in all +ZFAND4 ANUBL1, FLJ40185 ENSG00000172671 Zinc finger AN1-type containing 4 10 45615501-45672780 Predicted intracellular proteins Evidence at transcript level HPA037839, HPA057543 Uncertain Approved Golgi apparatus Expressed in all Tissue enriched 13 testis: 95.4 lymph node: 7.5 Cell line enhanced Daudi: 32.0 +THEMIS bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA ENSG00000172673 Thymocyte selection associated 6 127708072-127918631 Predicted intracellular proteins Evidence at protein level HPA031422, HPA031425 Enhanced Mixed Tissue enhanced lymph node: 8.4 cerebral cortex,spleen: 4.5 Cell line enhanced HDLM-2: 30.2;MOLT-4: 41.2;RPMI-8226: 15.0 +MOS ENSG00000172680 MOS proto-oncogene, serine/threonine kinase 8 56112942-56113982 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040424 Uncertain Not detected Not detected testis: 0.8 Not detected +ZNF738 ENSG00000172687 Zinc finger protein 738 19 21358930-21379302 Predicted intracellular proteins Evidence at protein level HPA059135 Uncertain Ovarian cancer:2.27e-4 (favourable) Mixed Mixed ovary: 11.7 Mixed +MS4A10 CD20L7, MS4A9 ENSG00000172689 Membrane spanning 4-domains A10 11 60785348-60801305 Predicted membrane proteins, Transporters Evidence at transcript level HPA014778 Uncertain Not detected Group enriched 193 duodenum: 74.2;small intestine: 95.8 kidney: 0.4 Not detected +SLFN11 FLJ34922 ENSG00000172716 Schlafen family member 11 17 35350305-35373701 Predicted intracellular proteins Evidence at protein level HPA023030, HPA062062 Uncertain Enhanced Nucleoplasm Renal cancer:9.93e-10 (unfavourable) Expressed in all Expressed in all lung: 56.0 Mixed +FAM71D C14orf54 ENSG00000172717 Family with sequence similarity 71 member D 14 67189393-67228550 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 34 testis: 24.1 skin: 0.7 Cell line enhanced U-2 OS: 1.1 +CCL19 CKb11, ELC, exodus-3, MIP-3b, SCYA19 ENSG00000172724 C-C motif chemokine ligand 19 9 34689567-34691277 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA067758 Enhanced Renal cancer:8.63e-7 (unfavourable), Cervical cancer:9.91e-6 (favourable), Breast cancer:2.88e-5 (favourable) Expressed in all Group enriched 5 adipose tissue: 173.8;appendix: 771.8;lymph node: 703.2;tonsil: 556.0 gallbladder: 107.9 Cell line enhanced HDLM-2: 2.9;TIME: 1.2 +CORO1B coronin-2 ENSG00000172725 Coronin 1B 11 67435510-67443821 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017616, HPA040113, HPA070456 Enhanced Enhanced Plasma membrane
Cytosol Endometrial cancer:1.65e-4 (favourable) Expressed in all Expressed in all prostate: 85.9 Mixed +FUT10 ENSG00000172728 Fucosyltransferase 10 8 33370824-33473422 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053970, HPA058655 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Golgi apparatus Mixed Mixed parathyroid gland: 8.7 Mixed +LRRC20 FLJ10751, FLJ10844 ENSG00000172731 Leucine rich repeat containing 20 10 70298970-70382650 Predicted intracellular proteins Evidence at protein level HPA039630 Approved Nucleoplasm
Cytosol Renal cancer:1.41e-4 (favourable) Expressed in all Tissue enhanced skeletal muscle: 120.5 heart muscle: 28.5 Cell line enhanced U-2 OS: 83.3 +MUS81 FLJ44872, SLX3 ENSG00000172732 MUS81 structure-specific endonuclease subunit 11 65857126-65867653 Predicted intracellular proteins Evidence at protein level HPA059530 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:6.05e-4 (unfavourable) Expressed in all Expressed in all endometrium: 25.0 Expressed in all +PURG PURG-A, PURG-B ENSG00000172733 Purine rich element binding protein G 8 30995802-31033715 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047746 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Tissue enhanced Tissue enhanced cerebral cortex: 6.6;testis: 4.8 endometrium: 2.6 Cell line enhanced AF22: 6.0;NTERA-2: 4.8;SH-SY5Y: 6.0 +TMEM217 C6orf128, dJ355M6.2 ENSG00000172738 Transmembrane protein 217 6 37212180-37258155 Predicted membrane proteins Evidence at protein level HPA045432, HPA071187, HPA074578 Supported Nucleoli Mixed Tissue enriched 14 testis: 14.2 adrenal gland: 1.0 Cell line enhanced HEL: 3.0;HUVEC TERT2: 2.8;TIME: 7.2 +OR4D9 ENSG00000172742 Olfactory receptor family 4 subfamily D member 9 11 59514913-59515857 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF596 ENSG00000172748 Zinc finger protein 596 8 232137-264703 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055463 Uncertain Approved Nucleoli
Mitochondria Mixed Tissue enhanced testis: 27.8 parathyroid gland: 12.9 Mixed +COL6A5 COL29A1, FLJ35880, VWA4 ENSG00000172752 Collagen type VI alpha 5 chain 3 130345516-130484844 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA043138 Uncertain Not detected Group enriched 6 lung: 3.8;skin: 7.4 duodenum,stomach: 0.9 Cell line enriched 73 HDLM-2: 14.7 +CFL1 CFL ENSG00000172757 Cofilin 1 11 65823022-65862026 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033687, CAB037077, HPA053761 Approved Liver cancer:1.73e-5 (unfavourable) Expressed in all Expressed in all appendix: 1225.4 Expressed in all +TMCC1 KIAA0779 ENSG00000172765 Transmembrane and coiled-coil domain family 1 3 129647792-129893576 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053894 Uncertain Renal cancer:1.77e-6 (unfavourable), Pancreatic cancer:1.87e-4 (unfavourable), Liver cancer:9.15e-4 (unfavourable) Expressed in all Expressed in all testis: 25.2 Expressed in all +NAA16 FLJ22054, MGC40612, NARG1L, PRO2435 ENSG00000172766 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 13 41311205-41377030 Predicted intracellular proteins Evidence at protein level HPA039761, HPA040157 Approved Enhanced Cytosol Expressed in all Expressed in all bone marrow: 14.4 Expressed in all +OR5B3 OR5B13, OST129 ENSG00000172769 Olfactory receptor family 5 subfamily B member 3 11 58402464-58403409 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +EFCAB12 C3orf25 ENSG00000172771 EF-hand calcium binding domain 12 3 129401321-129428651 Predicted intracellular proteins Evidence at protein level HPA037694 Uncertain Supported Mixed Group enriched 5 fallopian tube: 31.3;testis: 6.7 prostate: 3.7 Cell line enhanced Hep G2: 1.0;SCLC-21H: 1.0 +OR10W1 OR10W1P ENSG00000172772 Olfactory receptor family 10 subfamily W member 1 11 58266792-58268260 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +FAM192A C16orf94, NIP30 ENSG00000172775 Family with sequence similarity 192 member A 16 57152466-57186116 Predicted intracellular proteins Evidence at protein level HPA054382, HPA059652 Uncertain Supported Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 175.9 Expressed in all +RAB43 ISY1, RAB11B, RAB41 ENSG00000172780 RAB43, member RAS oncogene family 3 129087569-129122801 Predicted intracellular proteins Evidence at protein level HPA046840, HPA060085 Enhanced Supported Plasma membrane Mixed Mixed thyroid gland: 37.3 Mixed +FADS6 ENSG00000172782 Fatty acid desaturase 6 17 74877299-74893781 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA016802 Uncertain Tissue enhanced Tissue enhanced epididymis: 21.9 small intestine: 10.1 Mixed +CBWD1 ENSG00000172785 COBW domain containing 1 9 121038-179147 Predicted intracellular proteins Evidence at transcript level HPA042759, HPA042813 Approved Approved Plasma membrane Mixed Expressed in all adrenal gland: 44.8 Mixed +HOXC5 HOX3, HOX3D ENSG00000172789 Homeobox C5 12 54032853-54035358 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026794 Uncertain Supported Nucleoplasm Tissue enhanced Tissue enhanced fallopian tube: 6.0 ovary: 3.1 Cell line enhanced AN3-CA: 5.6;SH-SY5Y: 7.0 +RAB37 ENSG00000172794 RAB37, member RAS oncogene family 17 74670578-74747335 Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:8.80e-6 (unfavourable), Testis cancer:9.27e-4 (unfavourable) Mixed Mixed spleen: 20.9 Cell line enhanced HEL: 47.0;HMC-1: 48.4;U-266/70: 61.0;U-937: 27.5 +DCP2 NUDT20 ENSG00000172795 Decapping mRNA 2 5 112976702-113020970 Enzymes, Predicted intracellular proteins Evidence at protein level CAB011677, HPA057676 Approved Approved Nucleoplasm
Cell Junctions
Cytoplasmic bodies Renal cancer:2.66e-5 (unfavourable), Liver cancer:4.84e-4 (unfavourable) Expressed in all Mixed placenta: 18.9 Expressed in all +SNX32 FLJ30934, SNX6B ENSG00000172803 Sorting nexin 32 11 65833641-65856896 Predicted intracellular proteins Evidence at protein level HPA041775 Uncertain Uncertain Cell Junctions
Focal adhesion sites Mixed Tissue enhanced cerebral cortex: 7.7 testis: 1.8 Cell line enhanced HHSteC: 3.0;HSkMC: 3.4;SH-SY5Y: 1.9;U-266/70: 4.3 +RPL38 L38 ENSG00000172809 Ribosomal protein L38 17 74203582-74210655 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA052543 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:6.17e-8 (unfavourable), Head and neck cancer:2.51e-4 (unfavourable) Expressed in all Expressed in all ovary: 2584.8 Expressed in all +CYP7B1 SPG5A ENSG00000172817 Cytochrome P450 family 7 subfamily B member 1 8 64587763-64798761 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA017761 Uncertain Mixed Tissue enhanced parathyroid gland: 40.3 thyroid gland: 22.4 Cell line enhanced HSkMC: 11.3;SH-SY5Y: 6.2;WM-115: 11.7 +OVOL1 HOVO1 ENSG00000172818 Ovo like transcriptional repressor 1 11 65787022-65797219 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003984 Uncertain Approved Nucleus Renal cancer:1.00e-13 (favourable), Endometrial cancer:1.87e-4 (unfavourable) Mixed Tissue enhanced esophagus: 37.3;skin: 33.4;testis: 35.3 urinary bladder: 15.5 Cell line enhanced A-431: 16.3;BEWO: 49.5;HaCaT: 27.3;RT4: 24.5;SK-BR-3: 17.8 +RARG NR1B3, RARC ENSG00000172819 Retinoic acid receptor gamma 12 53210567-53232980 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053883 Supported Supported Nucleoplasm Renal cancer:3.08e-6 (unfavourable), Endometrial cancer:3.68e-6 (unfavourable) Expressed in all Tissue enhanced skin: 143.4 esophagus: 77.3 Mixed +CES4A CES8, FLJ37464 ENSG00000172824 Carboxylesterase 4A 16 66988589-67009758 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035701 Approved Approved Cytosol Renal cancer:2.35e-6 (unfavourable) Mixed Group enriched 7 fallopian tube: 28.9;skin: 9.2 epididymis: 2.7 Cell line enhanced HDLM-2: 17.6;SiHa: 4.2 +CES3 ES31, FLJ21736 ENSG00000172828 Carboxylesterase 3 16 66961237-66975148 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041008, HPA041307 Approved Approved Nuclear membrane
Endoplasmic reticulum Liver cancer:7.26e-5 (favourable) Mixed Tissue enhanced colon: 37.2;duodenum: 30.5;rectum: 34.1 small intestine: 26.6 Cell line enhanced AN3-CA: 7.1 +SSH3 FLJ10928, FLJ20515 ENSG00000172830 Slingshot protein phosphatase 3 11 67303448-67312607 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019949, HPA019957 Approved Approved Nuclear speckles
Plasma membrane
Actin filaments
Cytosol Pancreatic cancer:2.89e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 37.5 Cell line enhanced RT4: 69.9 +CES2 CE-2, CES2A1, iCE ENSG00000172831 Carboxylesterase 2 16 66934444-66945096 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018897 Enhanced Approved Golgi apparatus
Cytosol Renal cancer:1.50e-5 (favourable) Expressed in all Expressed in all duodenum: 527.2 Expressed in all +PDP2 KIAA1348, PPM2B, PPM2C2 ENSG00000172840 Pyruvate dehyrogenase phosphatase catalytic subunit 2 16 66878589-66895754 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019950, HPA062059 Approved Supported Mitochondria Renal cancer:9.75e-7 (favourable) Expressed in all Mixed thyroid gland: 15.5 Expressed in all +SP3 SPR-2 ENSG00000172845 Sp3 transcription factor 2 173906459-173965702 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004580, HPA032145, HPA032146 Supported Supported Renal cancer:2.46e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 91.7 Expressed in all +KRT2 KRT2A, KRTE ENSG00000172867 Keratin 2 12 52644558-52652164 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006299, CAB037321 Enhanced Approved Golgi apparatus
Intermediate filaments
Cytosol Group enriched Tissue enriched 23 skin: 2600.1 breast: 112.2 Cell line enhanced HEL: 1.9 +DMXL1 ENSG00000172869 Dmx like 1 5 119037772-119249138 Predicted intracellular proteins Evidence at protein level HPA036431, HPA036432 Approved Supported Nucleoli
Cytosol Renal cancer:5.16e-5 (favourable) Expressed in all Mixed prostate: 43.4 Expressed in all +METAP1D MAP1D, Metap1l ENSG00000172878 Methionyl aminopeptidase type 1D, mitochondrial 2 171999583-172082430 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030298, HPA030299 Uncertain Supported Vesicles Expressed in all Mixed ovary: 9.3 Expressed in all +ZNF621 FLJ45246 ENSG00000172888 Zinc finger protein 621 3 40524878-40574685 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA065518, HPA071440 Supported Nuclear speckles Expressed in all Expressed in all parathyroid gland: 22.6 Expressed in all +EGFL7 ZNEU1 ENSG00000172889 EGF like domain multiple 7 9 136658856-136672678 Predicted secreted proteins Evidence at protein level HPA050716 Approved Colorectal cancer:4.22e-6 (unfavourable), Renal cancer:5.28e-4 (unfavourable) Expressed in all Expressed in all placenta: 263.7 Cell line enhanced EFO-21: 172.9;HUVEC TERT2: 276.0;TIME: 254.4 +NADSYN1 FLJ10631 ENSG00000172890 NAD synthetase 1 11 71453109-71524107 Enzymes, Predicted intracellular proteins Evidence at protein level CAB017798, HPA038523, HPA038524 Approved Enhanced Cytosol Liver cancer:5.17e-6 (unfavourable), Renal cancer:8.72e-5 (unfavourable), Urothelial cancer:5.10e-4 (favourable) Expressed in all Expressed in all bone marrow: 41.7 Expressed in all +DHCR7 SLOS ENSG00000172893 7-dehydrocholesterol reductase 11 71428193-71452868 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA044280 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:6.93e-7 (favourable), Urothelial cancer:5.67e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 115.2 Expressed in all +LVRN APQ, AQPEP, FLJ90650, TAQPEP ENSG00000172901 Laeverin 5 115962454-116027619 Enzymes, Predicted secreted proteins Evidence at protein level HPA053254 Enhanced Not detected Group enriched 22 adipose tissue: 11.8;placenta: 31.5 breast: 1.0 Not detected +NBEA BCL8B, FLJ10197, KIAA1544, LYST2 ENSG00000172915 Neurobeachin 13 34942287-35673022 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039730, HPA040385 Enhanced Supported Nucleus
Nucleoli
Golgi apparatus
Cytosol Renal cancer:7.86e-8 (favourable) Mixed Tissue enhanced cerebral cortex: 30.3 seminal vesicle: 12.2 Cell line enriched 5 SH-SY5Y: 83.5 +RNASEH2C AGS3, AYP1 ENSG00000172922 Ribonuclease H2 subunit C 11 65714896-65720947 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065375 Approved Nucleus Pancreatic cancer:3.68e-5 (favourable), Renal cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 25.1 Expressed in all +MYEOV OCIM ENSG00000172927 Myeloma overexpressed 11 69294138-69367726 Predicted membrane proteins Evidence at transcript level HPA012949 Uncertain Approved Nucleus
Vesicles Pancreatic cancer:1.54e-7 (unfavourable), Renal cancer:1.48e-5 (unfavourable), Lung cancer:2.00e-4 (unfavourable) Mixed Group enriched 5 adipose tissue: 4.0;breast: 5.8;esophagus: 9.2;skin: 1.8;stomach: 6.8 appendix: 1.0 Cell line enhanced A-431: 154.1;A549: 74.9;U-2 OS: 38.7 +ANKRD13D ENSG00000172932 Ankyrin repeat domain 13D 11 67288547-67302485 Predicted intracellular proteins Evidence at protein level HPA039950 Approved Approved Nucleus
Mitochondria Renal cancer:5.73e-10 (unfavourable) Expressed in all Expressed in all bone marrow: 69.4 Expressed in all +MRGPRF GPR140, GPR168, MGC21621, mrgF ENSG00000172935 MAS related GPR family member F 11 69004395-69013409 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA028811 Approved Supported Nuclear membrane
Plasma membrane Expressed in all Mixed smooth muscle: 78.8 Cell line enhanced ASC diff: 43.0;BJ: 31.1;BJ hTERT+: 74.9;BJ hTERT+ SV40 Large T+: 31.7;U-2197: 40.5 +MYD88 ENSG00000172936 Myeloid differentiation primary response 88 3 38138478-38143022 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009104 Approved Supported Vesicles
Mitochondria
Cytosol Breast cancer:8.45e-4 (favourable) Expressed in all Mixed lung: 57.1 Expressed in all +MRGPRD mrgD ENSG00000172938 MAS related GPR family member D 11 68980021-68980986 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA031346 Uncertain Not detected Not detected seminal vesicle: 0.3 Not detected +OXSR1 KIAA1101, OSR1 ENSG00000172939 Oxidative stress responsive 1 3 38165089-38255488 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008237, CAB017181 Enhanced Enhanced Cytosol Expressed in all Expressed in all parathyroid gland: 43.0 Expressed in all +SLC22A13 OAT10, OCTL1, OCTL3, ORCTL3 ENSG00000172940 Solute carrier family 22 member 13 3 38265812-38278315 Predicted membrane proteins, Transporters Evidence at protein level HPA035603, HPA035962 Enhanced Tissue enriched Tissue enriched 39 kidney: 10.7 testis: 0.2 Not detected +PHF8 JHDM1F, KDM7B, KIAA1111, ZNF422 ENSG00000172943 PHD finger protein 8 X 53936676-54048958 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038779, HPA062015 Approved Supported Nucleus Urothelial cancer:3.74e-5 (favourable) Expressed in all Expressed in all epididymis: 85.8 Expressed in all +LCLAT1 AGPAT8, ALCAT1, FLJ37965, LYCAT ENSG00000172954 Lysocardiolipin acyltransferase 1 2 30447226-30644225 Enzymes, Predicted membrane proteins Evidence at protein level HPA031880, HPA049217 Uncertain Supported Endoplasmic reticulum
Cytosol Liver cancer:8.72e-4 (unfavourable), Head and neck cancer:9.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 18.8 Expressed in all +ADH6 ADH-5 ENSG00000172955 Alcohol dehydrogenase 6 (class V) 4 99202638-99219537 Enzymes, Predicted intracellular proteins Evidence at protein level HPA067946, HPA069081 Enhanced Tissue enriched Tissue enriched 7 liver: 359.6 kidney: 53.5 Group enriched 8 Hep G2: 30.3;RPTEC TERT1: 6.8 +XKR3 MGC57211, XTES ENSG00000172967 XK related 3 22 16783412-16821699 Predicted membrane proteins, Transporters Evidence at transcript level HPA003379, HPA035081 Uncertain Not detected Tissue enriched 81 testis: 14.4 cerebral cortex: 0.1 Cell line enriched 12 Karpas-707: 165.9 +FRG2C ENSG00000172969 FSHD region gene 2 family member C 3 75664330-75667220 Predicted intracellular proteins Evidence at transcript level HPA039264, HPA047769 Uncertain Not detected Tissue enhanced testis: 1.0 kidney: 0.6 Cell line enriched 17 HDLM-2: 11.8 +KAT5 cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5 ENSG00000172977 Lysine acetyltransferase 5 11 65711996-65719604 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016953 Approved Supported Nucleoplasm Renal cancer:1.10e-13 (favourable) Expressed in all Expressed in all parathyroid gland: 84.4 Expressed in all +SH3RF3 FLJ00204, POSH2, SH3MD4 ENSG00000172985 SH3 domain containing ring finger 3 2 109129348-109504632 Predicted secreted proteins Evidence at protein level HPA044822, HPA048444 Approved Enhanced Nucleoplasm
Centrosome
Cytosol Ovarian cancer:2.33e-4 (unfavourable) Expressed in all Mixed placenta: 7.6 Cell line enhanced TIME: 19.3;U-266/84: 20.2 +GXYLT2 GLT8D4 ENSG00000172986 Glucoside xylosyltransferase 2 3 72888073-72998138 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA068429 Uncertain Approved Nucleoplasm
Cytokinetic bridge
Midbody ring Renal cancer:1.46e-7 (unfavourable), Urothelial cancer:2.42e-5 (unfavourable) Mixed Mixed ovary: 20.6 Cell line enhanced MOLT-4: 29.2 +HPSE2 HPA2, HPR2, UFS ENSG00000172987 Heparanase 2 (inactive) 10 98457077-99235862 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044603 Uncertain Tissue enhanced Tissue enhanced cervix, uterine: 53.4 prostate: 22.8 Group enriched 24 BJ hTERT+: 11.3;HEL: 23.9 +DCAKD FLJ22955 ENSG00000172992 Dephospho-CoA kinase domain containing 17 45023340-45061109 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060997 Approved Nucleus Endometrial cancer:7.16e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 47.1 Expressed in all +ARPP21 ARPP-21, R3HDM3, TARPP ENSG00000172995 CAMP regulated phosphoprotein 21 3 35638945-35794496 Predicted intracellular proteins Evidence at protein level HPA017303 Enhanced Approved Nucleoli
Cytosol Tissue enhanced Tissue enriched 6 cerebral cortex: 127.1 skeletal muscle: 20.2 Group enriched 10 MOLT-4: 54.6;REH: 34.0;RH-30: 19.9 +TADA2B MGC21874 ENSG00000173011 Transcriptional adaptor 2B 4 7041899-7057952 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035770 Approved Approved Nuclear speckles Renal cancer:7.17e-11 (favourable), Urothelial cancer:1.59e-4 (favourable) Expressed in all Expressed in all thyroid gland: 27.4 Expressed in all +CCDC96 FLJ90575 ENSG00000173013 Coiled-coil domain containing 96 4 7040849-7042939 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047546 Enhanced Renal cancer:3.80e-5 (favourable), Endometrial cancer:4.05e-4 (favourable), Pancreatic cancer:4.87e-4 (favourable) Expressed in all Group enriched 14 fallopian tube: 17.7;testis: 61.7 cerebral cortex,lung: 2.7 Mixed +GRK2 ADRBK1, BARK1 ENSG00000173020 G protein-coupled receptor kinase 2 11 67266410-67286556 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005021, CAB037248, HPA048330 Approved Approved Vesicles Renal cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all spleen: 127.3 Expressed in all +RELA NFKB3, p65 ENSG00000173039 RELA proto-oncogene, NF-kB subunit 11 65653596-65663094 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level CAB004264, CAB005030, HPA063461 Supported Enhanced Cytosol Renal cancer:5.66e-4 (unfavourable), Liver cancer:9.18e-4 (unfavourable) Expressed in all Expressed in all endometrium: 62.5 Expressed in all +EVC2 LBN ENSG00000173040 EvC ciliary complex subunit 2 4 5542772-5709548 Disease related genes, Predicted membrane proteins Evidence at protein level HPA040910, HPA048122 Uncertain Approved Mitochondria Renal cancer:1.58e-4 (favourable) Mixed Mixed ovary: 8.8 Cell line enhanced HHSteC: 10.9 +ZNF680 FLJ90430 ENSG00000173041 Zinc finger protein 680 7 64519884-64563106 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA003173 Approved Nucleus Expressed in all Expressed in all thyroid gland: 42.5 Mixed +HECTD4 C12orf51, FLJ34154, KIAA0614 ENSG00000173064 HECT domain E3 ubiquitin protein ligase 4 12 112160188-112382439 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041062, HPA045473 Uncertain Approved Nucleoplasm
Vesicles Head and neck cancer:2.97e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 19.4 Expressed in all +FAM222B C17orf63, FLJ10700 ENSG00000173065 Family with sequence similarity 222 member B 17 28755978-28855232 Predicted intracellular proteins Evidence at protein level HPA051840, HPA062239 Approved Enhanced Nucleoplasm Liver cancer:3.45e-4 (unfavourable) Expressed in all Expressed in all testis: 50.9 Expressed in all +BNC2 BSN2, FLJ20043 ENSG00000173068 Basonuclin 2 9 16409503-16870843 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018525, HPA059419 Approved Supported Nucleoplasm Mixed Tissue enhanced endometrium: 44.5;ovary: 39.4;smooth muscle: 48.0 fallopian tube: 19.3 Mixed +DEC1 CTS9 ENSG00000173077 Deleted in esophageal cancer 1 9 115141818-115402644 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.5 Not detected +RXFP4 GPCR142, GPR100, RLN3R2, RXFPR4 ENSG00000173080 Relaxin/insulin like family peptide receptor 4 1 155941710-155942949 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced colon: 2.0;duodenum: 1.4;rectum: 2.2 small intestine: 1.1 Not detected +HPSE HPA, HPSE1, HSE1 ENSG00000173083 Heparanase 4 83292461-83335153 Enzymes, Predicted secreted proteins Evidence at protein level CAB009813, HPA055344 Enhanced Nucleoplasm
Vesicles Mixed Tissue enhanced parathyroid gland: 20.0 testis: 10.0 Cell line enhanced Karpas-707: 27.7 +COQ2 CL640, FLJ26072 ENSG00000173085 Coenzyme Q2, polyprenyltransferase 4 83261536-83284914 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA056599, HPA068727 Approved Approved Cytosol Expressed in all Expressed in all adrenal gland: 18.4 Expressed in all +CCDC63 FLJ35843, ODA5 ENSG00000173093 Coiled-coil domain containing 63 12 110846769-110907535 Predicted intracellular proteins Evidence at protein level HPA061568 Approved Nucleoplasm
Nuclear bodies
Vesicles Tissue enriched Tissue enriched 28 testis: 29.6 heart muscle: 1.0 Cell line enriched 14 MCF7: 3.3 +HSPA6 HSP70B' ENSG00000173110 Heat shock protein family A (Hsp70) member 6 1 161524540-161526910 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017452, HPA028549, HPA052504 Approved Approved Nucleoplasm
Vesicles Renal cancer:1.98e-5 (unfavourable), Liver cancer:7.26e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 27.8 spleen: 15.1 Cell line enriched 7 Karpas-707: 36.1 +TRMT112 HSPC152, HSPC170, hTrm112, TRM112, TRMT11-2 ENSG00000173113 TRNA methyltransferase 11-2 homolog (S. cerevisiae) 11 64316460-64318084 Predicted intracellular proteins Evidence at protein level HPA039901, HPA040006 Uncertain Approved Nucleus
Microtubules Head and neck cancer:1.62e-4 (unfavourable), Renal cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 306.4 Expressed in all +LRRN3 FIGLER5, FLJ11129, NLRR3 ENSG00000173114 Leucine rich repeat neuronal 3 7 111091006-111125454 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA043820, HPA046792 Uncertain Approved Nucleus
Cytosol Group enriched Tissue enhanced adrenal gland: 30.8;cerebral cortex: 31.2;testis: 29.1;thyroid gland: 33.6 lung: 11.6 Cell line enhanced AF22: 24.9;BJ hTERT+: 25.6;SH-SY5Y: 47.7;T-47d: 23.4 +KDM2A CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA ENSG00000173120 Lysine demethylase 2A 11 67119269-67258087 Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB012272, HPA044251 Supported Approved Nucleus Expressed in all Expressed in all testis: 60.0 Expressed in all +ACSM6 bA310E22.3, C10orf129 ENSG00000173124 Acyl-CoA synthetase medium-chain family member 6 10 95194200-95228928 Enzymes, Predicted membrane proteins Evidence at protein level HPA044593 Uncertain Urothelial cancer:7.71e-4 (favourable) Tissue enriched Tissue enhanced stomach: 1.7 urinary bladder: 0.6 Cell line enriched 27 RT4: 3.0 +ADCK5 FLJ35454 ENSG00000173137 AarF domain containing kinase 5 8 144373101-144393242 Enzymes, Predicted membrane proteins Evidence at protein level HPA025692, HPA028679 Approved Approved Plasma membrane
Cytosol Expressed in all Mixed duodenum: 9.6 Mixed +MRPL57 MRP63 ENSG00000173141 Mitochondrial ribosomal protein L57 13 21176645-21179084 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA039779, HPA059370 Enhanced Supported Mitochondria Pancreatic cancer:8.35e-4 (favourable) Expressed in all Expressed in all adrenal gland: 21.8 Expressed in all +NOC3L AD24, C10orf117, FAD24, FLJ12820 ENSG00000173145 NOC3 like DNA replication regulator 10 94333226-94362959 Predicted intracellular proteins Evidence at protein level HPA063958, HPA067638, HPA070981 Enhanced Nucleus
Nucleoli Expressed in all Expressed in all testis: 19.2 Expressed in all +ESRRA ERR1, ERRa, ERRalpha, ESRL1, NR3B1 ENSG00000173153 Estrogen related receptor alpha 11 64305572-64316743 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053785 Supported Nucleus
Nucleoli fibrillar center
Microtubules
Cytokinetic bridge Renal cancer:1.34e-7 (favourable) Expressed in all Expressed in all duodenum: 86.6 Expressed in all +RHOD ARHD, Rho, RhoD, RhoHP1 ENSG00000173156 Ras homolog family member D 11 67056818-67072013 Predicted intracellular proteins Evidence at protein level Lung cancer:3.10e-4 (unfavourable), Cervical cancer:9.17e-4 (unfavourable) Expressed in all Mixed esophagus: 37.0 Cell line enhanced A-431: 131.9;HaCaT: 116.3;HBEC3-KT: 125.2;hTCEpi: 146.2;T-47d: 136.0 +ADAMTS20 GON-1 ENSG00000173157 ADAM metallopeptidase with thrombospondin type 1 motif 20 12 43353866-43551921 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027608, HPA027609 Uncertain Not detected Not detected placenta: 0.8 Cell line enhanced Karpas-707: 2.6;NTERA-2: 2.8;U-266/70: 3.1;U-266/84: 1.5 +COMMD1 C2orf5, MGC27155, MURR1 ENSG00000173163 Copper metabolism domain containing 1 2 61888724-62147247 Predicted intracellular proteins Evidence at protein level HPA034633, HPA049223 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 47.8 Expressed in all +RAPH1 ALS2CR18, ALS2CR9, KIAA1681 ENSG00000173166 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 203394345-203535410 Predicted intracellular proteins Evidence at protein level HPA016744, HPA020027 Approved Approved Nuclear bodies
Plasma membrane
Cytosol Mixed Expressed in all thyroid gland: 50.0 Mixed +MTX1 MTX, MTXN ENSG00000173171 Metaxin 1 1 155208699-155213824 Predicted membrane proteins Evidence at protein level HPA011543 Uncertain Supported Mitochondria Renal cancer:3.39e-4 (unfavourable) Expressed in all Expressed in all testis: 71.8 Expressed in all +ADCY5 AC5 ENSG00000173175 Adenylate cyclase 5 3 123282296-123449758 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017730, HPA077682 Uncertain Enhanced Intermediate filaments Renal cancer:7.46e-6 (favourable) Mixed Tissue enhanced heart muscle: 69.1 prostate,seminal vesicle: 30.0 Cell line enhanced MCF7: 11.9;RPTEC TERT1: 4.0 +PARP14 KIAA1268, pART8 ENSG00000173193 Poly(ADP-ribose) polymerase family member 14 3 122680618-122730840 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008846, HPA012063 Supported Enhanced Cytosol Renal cancer:1.79e-4 (unfavourable) Expressed in all Expressed in all spleen: 51.1 Cell line enhanced BJ hTERT+ SV40 Large T+: 67.0;BJ hTERT+ SV40 Large T+ RasG12V: 107.2 +CYSLTR1 CysLT(1), CysLT1, CYSLT1R ENSG00000173198 Cysteinyl leukotriene receptor 1 X 78271464-78327691 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA010546 Approved Mixed Mixed spleen: 14.8 Cell line enhanced HL-60: 16.0;NB-4: 17.8;RPMI-8226: 29.5;THP-1: 17.5;U-937: 22.4 +PARP15 FLJ40597, pART7 ENSG00000173200 Poly(ADP-ribose) polymerase family member 15 3 122577602-122639047 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035757 Approved Mitochondria Mixed Tissue enhanced lymph node: 55.0;spleen: 60.4;tonsil: 48.1 appendix: 35.3 Cell line enhanced HEL: 7.8;TIME: 8.4 +CKS1B CKS1, ckshs1 ENSG00000173207 CDC28 protein kinase regulatory subunit 1B 1 154974653-154979249 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA003424, HPA030762 Approved Supported Approved Nucleus
Vesicles
Mitochondria
Cytosol Renal cancer:6.03e-7 (unfavourable), Liver cancer:2.94e-5 (unfavourable), Melanoma:3.12e-5 (unfavourable), Thyroid cancer:4.87e-4 (favourable), Pancreatic cancer:6.13e-4 (unfavourable), Endometrial cancer:7.89e-4 (unfavourable) Expressed in all Expressed in all lymph node: 84.9 Expressed in all +ABCD2 ALDL1, ALDR, ALDRP ENSG00000173208 ATP binding cassette subfamily D member 2 12 39550033-39619751 Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Tissue enhanced adipose tissue: 16.7 cervix, uterine: 8.5 Group enriched 6 ASC diff: 8.0;HDLM-2: 15.7;Karpas-707: 20.8;SH-SY5Y: 18.5;U-266/70: 7.4 +AHSA2 AHA1, DKFZp564C236, Hch1 ENSG00000173209 Activator of HSP90 ATPase homolog 2 2 61177418-61191203 Predicted intracellular proteins Evidence at protein level HPA051137 Approved Approved Vesicles
Microtubules
Cytokinetic bridge Renal cancer:4.11e-6 (unfavourable), Urothelial cancer:1.85e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 44.1 Expressed in all +ABLIM3 KIAA0843 ENSG00000173210 Actin binding LIM protein family member 3 5 149141483-149260542 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003245 Approved Approved Nucleoplasm
Plasma membrane
Cell Junctions Renal cancer:1.28e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 79.4 adipose tissue: 63.7 Cell line enhanced TIME: 84.5 +MAB21L3 C1orf161, FLJ38716 ENSG00000173212 Mab-21 like 3 1 116111755-116135240 Predicted intracellular proteins Evidence at protein level HPA039551, HPA046187 Uncertain Approved Nucleoplasm Mixed Group enriched 5 esophagus: 7.5;skin: 7.2 colon,kidney,rectum: 1.3 Cell line enhanced BEWO: 3.7;EFO-21: 8.0;RT4: 10.4 +MFSD4B KIAA1919, MGC33953 ENSG00000173214 Major facilitator superfamily domain containing 4B 6 111259348-111271167 Predicted membrane proteins Evidence at protein level HPA031784 Approved Uncertain Intermediate filaments Expressed in all Mixed placenta: 5.0 Mixed +VANGL1 STB2 ENSG00000173218 VANGL planar cell polarity protein 1 1 115641953-115698224 Disease related genes, Predicted membrane proteins Evidence at protein level HPA025235, CAB076375 Approved Approved Plasma membrane Colorectal cancer:7.53e-4 (favourable), Pancreatic cancer:7.89e-4 (unfavourable) Expressed in all Mixed fallopian tube: 19.4 Mixed +GLRX GRX, GRX1 ENSG00000173221 Glutaredoxin 5 95751319-95823005 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008634, HPA046431, CAB069419 Approved Approved Plasma membrane
Cytosol Expressed in all Expressed in all kidney: 218.9 Expressed in all +IQCB1 KIAA0036, NPHP5, SLSN5 ENSG00000173226 IQ motif containing B1 3 121769763-121835079 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042028 Approved Supported Microtubules
Cytokinetic bridge
Mitotic spindle Liver cancer:3.08e-5 (unfavourable), Cervical cancer:1.77e-4 (favourable), Lung cancer:3.67e-4 (favourable) Expressed in all Expressed in all testis: 52.5 Expressed in all +SYT12 SRG1 ENSG00000173227 Synaptotagmin 12 11 67006778-67050863 Predicted intracellular proteins Evidence at protein level HPA011006 Uncertain Pancreatic cancer:4.13e-4 (unfavourable) Tissue enhanced Tissue enriched 7 parathyroid gland: 115.1 cerebral cortex: 17.2 Cell line enhanced HeLa: 31.9;MCF7: 25.6;SiHa: 44.9;SK-BR-3: 15.2;T-47d: 19.2 +GOLGB1 GCP, GCP372, giantin, GOLIM1 ENSG00000173230 Golgin B1 3 121663199-121749767 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011008, HPA011555 Enhanced Enhanced Golgi apparatus Expressed in all Expressed in all prostate: 41.9 Expressed in all +C11orf86 FLJ22675 ENSG00000173237 Chromosome 11 open reading frame 86 11 66975277-66977004 Predicted intracellular proteins Evidence at transcript level HPA039348 Uncertain Renal cancer:1.02e-5 (unfavourable), Pancreatic cancer:6.97e-5 (unfavourable), Lung cancer:8.97e-4 (unfavourable) Mixed Group enriched 7 duodenum: 68.2;small intestine: 70.9 colon: 10.3 Cell line enriched 5 SiHa: 26.4 +LIPM bA304I5.1, LIPL3 ENSG00000173239 Lipase family member M 10 88802730-88820546 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Pancreatic cancer:6.47e-4 (unfavourable) Mixed Tissue enriched 14 skin: 51.4 breast: 3.7 Cell line enhanced CAPAN-2: 3.0;HL-60: 1.6;NB-4: 1.1;RT4: 1.2;T-47d: 1.5;U-937: 1.2 +GPR151 GALR4, PGR7 ENSG00000173250 G protein-coupled receptor 151 5 146513103-146516190 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected cerebral cortex: 0.2 Not detected +DMRT2 ENSG00000173253 Doublesex and mab-3 related transcription factor 2 9 1049858-1057552 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at transcript level HPA029297 Uncertain Tissue enhanced Tissue enriched 7 parathyroid gland: 108.9 kidney: 16.2 Cell line enhanced HaCaT: 3.3;RH-30: 4.8;RPMI-8226: 13.4;SCLC-21H: 3.4;SK-MEL-30: 4.0;WM-115: 3.5 +ZNF483 KIAA1962, ZKSCAN16, ZSCAN48 ENSG00000173258 Zinc finger protein 483 9 111525159-111577844 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055041 Uncertain Approved Nucleoli Tissue enhanced Mixed cerebral cortex: 13.0 Cell line enhanced NTERA-2: 7.5;SCLC-21H: 5.1 +PLAC8L1 ENSG00000173261 PLAC8 like 1 5 146084386-146104369 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 10 testis: 31.1 skin: 3.0 Cell line enhanced AN3-CA: 5.5 +SLC2A14 GLUT14, SLC2A3P3 ENSG00000173262 Solute carrier family 2 member 14 12 7812512-7891148 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA006539 Supported Approved Plasma membrane Tissue enriched Tissue enriched 35 testis: 148.8 ovary: 4.2 Cell line enhanced BEWO: 17.9;CACO-2: 25.7 +GPR137 C11orf4, GPR137A, TM7SF1L1 ENSG00000173264 G protein-coupled receptor 137 11 64270062-64289500 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA062871 Uncertain Approved Nucleus
Nucleoli
Actin filaments Liver cancer:5.34e-4 (unfavourable), Pancreatic cancer:6.18e-4 (favourable) Expressed in all Expressed in all testis: 146.5 Expressed in all +SNCG BCSG1, persyn, SR ENSG00000173267 Synuclein gamma 10 86958618-86963260 Predicted intracellular proteins Evidence at protein level CAB001452, HPA014404, CAB040581 Enhanced Approved Renal cancer:2.29e-8 (unfavourable), Stomach cancer:7.15e-4 (unfavourable) Group enriched Tissue enhanced adipose tissue: 174.6;adrenal gland: 198.1;urinary bladder: 183.2 seminal vesicle: 114.9 Cell line enhanced CAPAN-2: 463.6;RT4: 350.3;T-47d: 106.9 +MMRN2 EMILIN3, EndoGlyx-1, FLJ13465 ENSG00000173269 Multimerin 2 10 86935540-86969481 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020741 Approved Approved Vesicles Expressed in all Expressed in all placenta: 101.6 Cell line enhanced CAPAN-2: 78.1;HUVEC TERT2: 155.0;TIME: 182.9 +MZT2A FAM128A, MOZART2A ENSG00000173272 Mitotic spindle organizing protein 2A 2 131464900-131492743 Predicted intracellular proteins Evidence at protein level HPA051758, HPA052623 Approved Supported Centrosome
Cytosol Renal cancer:3.04e-11 (unfavourable), Breast cancer:3.04e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 40.5 Mixed +TNKS PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1 ENSG00000173273 Tankyrase 8 9555914-9782346 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA025690 Approved Approved Nucleoplasm
Nuclear membrane Expressed in all Expressed in all testis: 52.8 Expressed in all +ZNF449 FLJ23614, ZSCAN19 ENSG00000173275 Zinc finger protein 449 X 135344796-135363152 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA018079 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 12.3 Mixed +ZBTB21 KIAA1227, ZNF295 ENSG00000173276 Zinc finger and BTB domain containing 21 21 41986831-42010387 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024655, HPA031757, HPA031758 Enhanced Enhanced Nucleus Expressed in all Mixed adrenal gland: 47.6 Expressed in all +PPP1R3B FLJ14005, GL, PPP1R4 ENSG00000173281 Protein phosphatase 1 regulatory subunit 3B 8 9136255-9151574 Predicted intracellular proteins Evidence at protein level HPA028731 Approved Approved Cytosol Renal cancer:4.08e-7 (unfavourable), Stomach cancer:6.03e-5 (unfavourable), Pancreatic cancer:1.31e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 151.3 Cell line enhanced HUVEC TERT2: 39.3;RPTEC TERT1: 46.9 +OR10K1 ENSG00000173285 Olfactory receptor family 10 subfamily K member 1 1 158465562-158466503 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA059125 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +GPR148 PGR6 ENSG00000173302 G protein-coupled receptor 148 2 130729070-130730336 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA060527 Uncertain Not detected Not detected stomach: 0.4 Not detected +STOX2 DKFZp762K222 ENSG00000173320 Storkhead box 2 4 183797692-184023526 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049776, HPA065002 Uncertain Uncertain Nucleoplasm
Actin filaments
Cytosol Mixed Tissue enhanced cerebral cortex: 17.4 parathyroid gland: 11.5 Cell line enhanced AF22: 13.0;NTERA-2: 16.8;SH-SY5Y: 16.8 +MAP3K11 MEKK11, MLK3, PTK1, SPRK ENSG00000173327 Mitogen-activated protein kinase kinase kinase 11 11 65597755-65615382 Enzymes, Predicted intracellular proteins Evidence at protein level CAB010165 Approved Supported Microtubule organizing center
Cytosol Expressed in all Expressed in all spleen: 54.7 Expressed in all +TRIB1 C8FW, GIG2, TRB1 ENSG00000173334 Tribbles pseudokinase 1 8 125430321-125438405 Enzymes, Predicted intracellular proteins Evidence at protein level HPA063982 Approved Plasma membrane Expressed in all Expressed in all bone marrow: 243.6 Cell line enhanced HEL: 173.6 +CST9 CLM, CTES7A ENSG00000173335 Cystatin 9 20 23602410-23605876 Predicted secreted proteins Evidence at transcript level HPA029190 Uncertain Tissue enriched Tissue enriched 12 breast: 2.1 kidney: 0.1 Not detected +KCNK7 K2p7.1 ENSG00000173338 Potassium two pore domain channel subfamily K member 7 11 65592855-65595996 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Voltage-gated ion channels Evidence at transcript level HPA077577 Approved Plasma membrane Tissue enhanced Tissue enriched 7 skin: 53.2 esophagus: 7.9 Cell line enhanced SCLC-21H: 8.4 +SFT2D3 MGC5391 ENSG00000173349 SFT2 domain containing 3 2 127701508-127705242 Predicted membrane proteins Evidence at protein level Not detected Mixed parathyroid gland: 7.9 Cell line enhanced ASC diff: 5.1;hTCEpi: 5.1 +RP11-330H6.5 ENSG00000173366 3 52221081-52231190 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced lymph node: 3.7;tonsil: 2.3 appendix,spleen: 1.9 Cell line enhanced Daudi: 9.9;RPMI-8226: 18.1;U-698: 8.8 +C1QB ENSG00000173369 Complement C1q B chain 1 22652762-22661538 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA052116 Approved Renal cancer:9.58e-6 (unfavourable) Expressed in all Expressed in all spleen: 1435.2 Not detected +C1QA ENSG00000173372 Complement C1q A chain 1 22636506-22639608 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002350, CAB009823 Supported Uncertain Golgi apparatus
Cytosol Renal cancer:1.58e-6 (unfavourable) Expressed in all Expressed in all spleen: 1166.4 Cell line enhanced HMC-1: 2.0;RPMI-8226: 4.9;SCLC-21H: 3.5 +NDNF C4orf31, FLJ23191 ENSG00000173376 Neuron derived neurotrophic factor 4 121035613-121073021 Predicted secreted proteins Evidence at protein level HPA048881 Supported Vesicles Renal cancer:3.26e-4 (unfavourable) Tissue enhanced Tissue enhanced lung: 159.9;placenta: 86.6 ovary: 52.7 Cell line enhanced fHDF/TERT166: 37.8;U-266/70: 16.0;U-266/84: 60.4 +IQCF1 MGC39725 ENSG00000173389 IQ motif containing F1 3 51894876-51903335 Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enriched 574 testis: 57.4 all non-specific tissues: 0.0 Not detected +OLR1 CLEC8A, LOX-1, SCARE1 ENSG00000173391 Oxidized low density lipoprotein receptor 1 12 10158301-10172138 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050798 Supported Nucleoplasm
Vesicles
Plasma membrane Head and neck cancer:8.24e-5 (unfavourable) Expressed in all Group enriched 6 appendix: 41.3;cerebral cortex: 32.7;lung: 146.3;placenta: 160.9 bone marrow: 15.8 Cell line enhanced CACO-2: 102.6;HHSteC: 104.1;SiHa: 261.9;SK-BR-3: 72.4 +GLIPR1L1 MGC26856 ENSG00000173401 GLI pathogenesis related 1 like 1 12 75334639-75370560 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042095 Enhanced Not detected Tissue enriched 45 testis: 78.3 skin: 1.7 Cell line enriched 100 NTERA-2: 109.3 +DAG1 156DAG, A3a, AGRNR, DAG ENSG00000173402 Dystroglycan 1 3 49468703-49535618 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB001960, CAB016353 Enhanced Supported Vesicles Renal cancer:2.59e-4 (favourable) Expressed in all Expressed in all placenta: 109.3 Expressed in all +INSM1 IA-1, IA1 ENSG00000173404 INSM transcriptional repressor 1 20 20368121-20370949 Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Tissue enhanced adrenal gland: 9.3;stomach: 5.6 duodenum: 3.0 Cell line enriched 32 SCLC-21H: 438.4 +DAB1 ENSG00000173406 DAB1, reelin adaptor protein 1 56994778-58546734 Predicted intracellular proteins Evidence at protein level CAB032329, HPA052033, HPA067495 Enhanced Supported Vesicles Mixed Tissue enhanced duodenum: 15.9;seminal vesicle: 13.8;small intestine: 24.8 prostate: 6.4 Cell line enhanced fHDF/TERT166: 41.8;HeLa: 12.9;NTERA-2: 23.4;RT4: 25.5;WM-115: 26.3 +ARV1 ENSG00000173409 ARV1 homolog, fatty acid homeostasis modulator 1 230978981-231000595 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA035709 Approved Approved Vesicles Lung cancer:3.27e-5 (favourable), Colorectal cancer:1.33e-4 (favourable) Expressed in all Expressed in all testis: 61.9 Expressed in all +NAA20 dJ1002M8.1, NAT3, NAT5 ENSG00000173418 N(alpha)-acetyltransferase 20, NatB catalytic subunit 20 20017116-20033655 Enzymes, Predicted intracellular proteins Evidence at protein level HPA063344 Supported Cytosol Head and neck cancer:1.96e-4 (unfavourable) Expressed in all Expressed in all esophagus: 82.5 Expressed in all +CCDC36 CT74, FLJ25320 ENSG00000173421 Coiled-coil domain containing 36 3 49198428-49258104 Predicted intracellular proteins Evidence at protein level HPA045690, HPA069534 Approved Approved Nucleoplasm Not detected Tissue enriched 14 testis: 48.6 adipose tissue: 3.5 Cell line enhanced hTEC/SVTERT24-B: 9.9;LHCN-M2: 3.5;U-2197: 5.0 +RNASE8 RAE2 ENSG00000173431 Ribonuclease A family member 8 14 21057822-21058455 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 105 salivary gland: 27.2 skin: 0.2 Not detected +SAA1 PIG4, SAA, TP53I4 ENSG00000173432 Serum amyloid A1 11 18266174-18269977 Disease related genes, Predicted secreted proteins Evidence at protein level Renal cancer:4.57e-12 (unfavourable) Tissue enriched Tissue enhanced adipose tissue: 3976.7;liver: 1183.1 cervix, uterine: 635.0 Group enriched 5 HBEC3-KT: 868.8;HHSteC: 212.1 +MINOS1 C1orf151, FLJ36999, Mic10, MIO10, RP5-1056L3.2 ENSG00000173436 Mitochondrial inner membrane organizing system 1 1 19596977-19629821 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059930 Enhanced Supported Mitochondria Liver cancer:7.23e-4 (unfavourable), Urothelial cancer:8.11e-4 (favourable) Expressed in all Expressed in all prostate: 13.1 Expressed in all +EHBP1L1 DKFZp762C186, TANGERIN ENSG00000173442 EH domain binding protein 1 like 1 11 65576038-65592650 Predicted intracellular proteins Evidence at protein level HPA039479 Approved Approved Nucleoli
Plasma membrane
Cytosol Renal cancer:1.45e-4 (unfavourable) Expressed in all Mixed skeletal muscle: 88.6 Mixed +THAP2 DKFZP564I0422 ENSG00000173451 THAP domain containing 2 12 71663009-71680639 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA039790 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all Mixed adrenal gland: 35.2 Expressed in all +TMEM196 MGC42090 ENSG00000173452 Transmembrane protein 196 7 19719310-19773598 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA043163 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 9.2 endometrium: 2.2 Group enriched 7 ASC diff: 3.1;ASC TERT1: 3.1 +RNF26 MGC2642 ENSG00000173456 Ring finger protein 26 11 119334527-119337313 Predicted membrane proteins Evidence at transcript level HPA027620 Uncertain Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:3.45e-6 (favourable), Liver cancer:3.19e-4 (unfavourable), Urothelial cancer:7.73e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.9 Mixed +PPP1R14B PHI-1, PLCB3N, PNG, SOM172 ENSG00000173457 Protein phosphatase 1 regulatory inhibitor subunit 14B 11 64244480-64246941 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053882 Approved Liver cancer:1.75e-6 (unfavourable), Pancreatic cancer:6.77e-4 (unfavourable) Expressed in all Expressed in all skin: 87.3 Expressed in all +RNASE11 C14orf6, RAJ1 ENSG00000173464 Ribonuclease A family member 11 (inactive) 14 20583559-20609884 Predicted secreted proteins Evidence at protein level HPA003724 Uncertain Not detected Tissue enriched 7 epididymis: 541.2 testis: 82.0 Not detected +SSSCA1 p27 ENSG00000173465 Sjogren syndrome/scleroderma autoantigen 1 11 65570430-65573942 Predicted intracellular proteins Evidence at protein level HPA039789, HPA064670 Uncertain Approved Cytosol Expressed in all Expressed in all cerebral cortex: 52.6 Expressed in all +AGR3 BCMP11, hAG-3, HAG3, PDIA18 ENSG00000173467 Anterior gradient 3, protein disulphide isomerase family member 7 16859405-16881987 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053942 Enhanced Supported Endoplasmic reticulum
Vesicles Tissue enhanced Tissue enhanced fallopian tube: 354.7;small intestine: 259.5 rectum: 233.8 Cell line enriched 52 T-47d: 316.6 +SMARCC1 BAF155, CRACC1, Rsc8, SRG3 ENSG00000173473 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 3 47585272-47782106 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB011576, CAB016336, HPA024352, HPA026853 Enhanced Enhanced Nucleoplasm Colorectal cancer:3.34e-4 (favourable), Liver cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all prostate: 36.1 Expressed in all +ZNF417 MGC34079 ENSG00000173480 Zinc finger protein 417 19 57900296-57916610 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042125, HPA043288, HPA056213 Uncertain Uncertain Nucleoplasm Urothelial cancer:3.48e-4 (favourable) Expressed in all Expressed in all epididymis: 59.9 Mixed +PTPRM hR-PTPu, PTPRL1, RPTPU ENSG00000173482 Protein tyrosine phosphatase, receptor type M 18 7566782-8406861 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003891, CAB022442, CAB022443 Supported Approved Plasma membrane Cervical cancer:8.65e-5 (unfavourable), Urothelial cancer:1.07e-4 (favourable) Expressed in all Mixed thyroid gland: 91.6 Mixed +FKBP2 FKBP-13, PPIase ENSG00000173486 FK506 binding protein 2 11 64241003-64244132 Enzymes, Predicted secreted proteins Evidence at protein level CAB025561, HPA049405 Enhanced Approved Plasma membrane Expressed in all Expressed in all epididymis: 399.2 Expressed in all +VEGFB VEGFL, VRF ENSG00000173511 Vascular endothelial growth factor B 11 64234538-64238793 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Expressed in all Expressed in all adipose tissue: 195.0 Expressed in all +PEAK1 KIAA2002, sgk269 ENSG00000173517 Pseudopodium enriched atypical kinase 1 15 77100656-77420144 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026313, HPA026517 Approved Expressed in all Mixed spleen: 40.6 Expressed in all +TNFRSF10D CD264, DcR2, TRAILR4, TRUNDD ENSG00000173530 TNF receptor superfamily member 10d 8 23135588-23164030 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level HPA070971 Approved Plasma membrane
Actin filaments Cervical cancer:1.70e-4 (unfavourable) Expressed in all Mixed gallbladder: 12.7 Cell line enhanced LHCN-M2: 208.5;WM-115: 234.5 +MST1 D3F15S2, DNF15S2, HGFL, MSP, NF15S2 ENSG00000173531 Macrophage stimulating 1 3 49683947-49689501 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA024036 Uncertain Pancreatic cancer:7.14e-4 (favourable) Tissue enriched Tissue enhanced liver: 144.2 duodenum: 51.1 Cell line enhanced Hep G2: 57.1;U-266/70: 16.6 +TNFRSF10C CD263, DcR1, LIT, TRAILR3, TRID ENSG00000173535 TNF receptor superfamily member 10c 8 23084355-23117437 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025635 Enhanced Mixed Tissue enhanced appendix: 21.9 spleen: 18.2 Group enriched 5 BEWO: 78.5;HUVEC TERT2: 56.8 +GMPPB KIAA1851 ENSG00000173540 GDP-mannose pyrophosphorylase B 3 49716844-49723951 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA014657 Uncertain Supported Nucleus Endometrial cancer:6.19e-6 (favourable), Renal cancer:3.17e-4 (favourable) Expressed in all Expressed in all thyroid gland: 42.0 Expressed in all +MOB1B MOB4A, MOBKL1A ENSG00000173542 MOB kinase activator 1B 4 70902326-71022449 Predicted intracellular proteins Evidence at protein level HPA047088, HPA071690 Supported Approved Nucleus
Nucleoli
Cytosol Liver cancer:4.92e-4 (unfavourable) Expressed in all Expressed in all kidney: 24.2 Expressed in all +ZNF622 MGC17552, MGC2485, ZPR9 ENSG00000173545 Zinc finger protein 622 5 16451519-16465792 Predicted intracellular proteins Evidence at protein level HPA036514, HPA036515 Uncertain Enhanced Nucleus
Nucleoli
Golgi apparatus
Cytosol Expressed in all Expressed in all heart muscle: 28.4 Expressed in all +CSPG4 HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2 ENSG00000173546 Chondroitin sulfate proteoglycan 4 15 75674322-75712848 Predicted membrane proteins Evidence at protein level HPA002951, CAB016189, HPA042785, HPA050008 Approved Approved Nucleus
Plasma membrane Renal cancer:7.60e-6 (unfavourable), Urothelial cancer:4.93e-5 (unfavourable) Expressed in all Mixed smooth muscle: 32.1 Cell line enhanced SK-MEL-30: 115.3;U-138 MG: 90.7;WM-115: 136.7 +SNX33 MGC32065, SH3PX3, SH3PXD3C, SNX30 ENSG00000173548 Sorting nexin 33 15 75647906-75662301 Predicted intracellular proteins Evidence at protein level HPA040988 Approved Ovarian cancer:5.24e-4 (unfavourable) Expressed in all Mixed fallopian tube: 26.6 Mixed +C2orf70 LOC339778 ENSG00000173557 Chromosome 2 open reading frame 70 2 26562582-26579532 Predicted intracellular proteins Evidence at protein level HPA062453 Enhanced Approved Nuclear membrane
Vesicles Pancreatic cancer:6.49e-4 (favourable) Mixed Group enriched 6 fallopian tube: 12.0;stomach: 4.9;testis: 17.5 thyroid gland: 1.9 Cell line enhanced A-431: 3.6;CAPAN-2: 2.7;EFO-21: 1.8;RPTEC TERT1: 2.8 +NABP1 DKFZp667M1322, FLJ13624, FLJ22833, hSSB2, MGC111163, OBFC2A, SOSS-B2, SSB2 ENSG00000173559 Nucleic acid binding protein 1 2 191678068-191696659 Predicted intracellular proteins Evidence at protein level HPA054978, HPA067802 Supported Nucleoplasm
Cytosol Renal cancer:8.20e-7 (unfavourable) Expressed in all Mixed appendix: 49.2 Mixed +ADGRF3 GPR113, hGPCR37, PGR23 ENSG00000173567 Adhesion G protein-coupled receptor F3 2 26308173-26346817 G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA044500 Uncertain Not detected Not detected kidney: 0.8 Mixed +NLRP13 CLR19.7, NALP13, NOD14, PAN13 ENSG00000173572 NLR family pyrin domain containing 13 19 55891699-55932336 Predicted intracellular proteins Evidence at protein level HPA060459 Uncertain Not detected Not detected breast: 0.7 Not detected +CHD2 DKFZp547I1315, DKFZp686E01200, DKFZp781D1727, FLJ38614 ENSG00000173575 Chromodomain helicase DNA binding protein 2 15 92900189-93028005 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA060744, HPA060960 Enhanced Enhanced Nucleus Expressed in all Expressed in all bone marrow: 48.3 Mixed +XCR1 CCXCR1, GPR5 ENSG00000173578 X-C motif chemokine receptor 1 3 46017024-46027742 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013169 Uncertain Mixed Tissue enhanced lymph node: 10.8 spleen: 9.1 Cell line enhanced Karpas-707: 1.8 +CCDC106 HSU79303 ENSG00000173581 Coiled-coil domain containing 106 19 55641062-55653161 Predicted intracellular proteins Evidence at protein level HPA041925, HPA043219 Uncertain Supported Nucleus
Cytosol Renal cancer:7.54e-11 (favourable), Pancreatic cancer:2.23e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 29.8 Cell line enhanced HEK 293: 77.4 +CCR9 CDw199, GPR-9-6, GPR28 ENSG00000173585 C-C motif chemokine receptor 9 3 45886504-45903177 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB006839 Uncertain Not detected Group enriched 6 appendix: 1.4;duodenum: 3.8;small intestine: 5.7;spleen: 1.2 lymph node,tonsil: 0.4 Cell line enriched 362 MOLT-4: 90.5 +CEP83 CCDC41, NPHP18, NY-REN-58 ENSG00000173588 Centrosomal protein 83 12 94306449-94459988 Predicted intracellular proteins Evidence at protein level HPA038161 Approved Approved Nucleus
Golgi apparatus Renal cancer:5.00e-10 (unfavourable), Prostate cancer:4.98e-4 (unfavourable) Expressed in all Expressed in all testis: 31.4 Expressed in all +SULT1B1 ST1B2 ENSG00000173597 Sulfotransferase family 1B member 1 4 69721162-69787961 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002107 Enhanced Approved Nucleoplasm
Golgi apparatus Group enriched Group enriched 5 colon: 68.9;duodenum: 99.0;rectum: 67.1;small intestine: 103.7;stomach: 41.6 appendix: 13.8 Group enriched 6 HUVEC TERT2: 92.0;TIME: 29.6;U-2197: 29.2 +NUDT4 DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, KIAA0487 ENSG00000173598 Nudix hydrolase 4 12 93377883-93408146 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017593, HPA047027, HPA057684 Approved Approved Cytosol Renal cancer:1.27e-4 (favourable) Expressed in all Expressed in all ovary: 184.7 Expressed in all +PC PCB ENSG00000173599 Pyruvate carboxylase 11 66848233-66958376 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033742, HPA043922, HPA058765 Uncertain Enhanced Mitochondria Ovarian cancer:7.86e-5 (unfavourable), Renal cancer:8.22e-5 (favourable) Expressed in all Expressed in all adipose tissue: 63.8 Mixed +UGT2A1 ENSG00000173610 UDP glucuronosyltransferase family 2 member A1 complex locus 4 69588417-69653249 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017261, HPA045108 Uncertain Tissue enhanced Group enriched 7 kidney: 8.1;liver: 5.5 skin: 0.9 Not detected +SCAI C9orf126, FLJ36664, NET40 ENSG00000173611 Suppressor of cancer cell invasion 9 124942608-125143506 Predicted intracellular proteins Evidence at protein level HPA020632 Approved Supported Nucleus
Nuclear membrane Mixed Mixed cerebral cortex: 11.7 Expressed in all +GPRC6A bA86F4.3 ENSG00000173612 G protein-coupled receptor class C group 6 member A 6 116792085-116829037 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Not detected kidney: 0.7 Cell line enhanced U-266/70: 1.2 +NMNAT1 LCA9, NMNAT, PNAT1 ENSG00000173614 Nicotinamide nucleotide adenylyltransferase 1 1 9943428-9985501 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA059447 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:3.85e-14 (favourable) Expressed in all Mixed thyroid gland: 12.5 Mixed +LRFN4 FIGLER6, MGC3103, SALM3. ENSG00000173621 Leucine rich repeat and fibronectin type III domain containing 4 11 66856647-66860475 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Expressed in all Mixed cerebral cortex: 13.3 Mixed +TRAPPC3L bA259P20.2, BET3L, FLJ11180 ENSG00000173626 Trafficking protein particle complex 3 like 6 116494989-116545610 Predicted intracellular proteins Evidence at protein level Not detected Mixed spleen: 6.5 Cell line enhanced Karpas-707: 4.7 +APOBEC4 C1orf169, FLJ25691, MGC26594, RP1-127C7.4 ENSG00000173627 Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 1 183646404-183653316 Predicted intracellular proteins Evidence at transcript level HPA015636, HPA015637 Approved Endometrial cancer:2.65e-4 (favourable) Tissue enhanced Group enriched 10 fallopian tube: 19.6;testis: 18.6 lung: 1.9 Not detected +SLC19A1 FOLT, RFC1 ENSG00000173638 Solute carrier family 19 member 1 21 45493572-45544411 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level HPA024802 Approved Approved Plasma membrane Renal cancer:1.07e-10 (unfavourable), Cervical cancer:4.15e-4 (unfavourable) Expressed in all Mixed duodenum: 22.0 Expressed in all +HSPB7 cvHSP ENSG00000173641 Heat shock protein family B (small) member 7 1 16014028-16019594 Predicted intracellular proteins Evidence at protein level HPA027639 Approved Approved Nucleoplasm Urothelial cancer:1.26e-4 (unfavourable), Head and neck cancer:5.29e-4 (unfavourable) Mixed Tissue enhanced heart muscle: 1571.0;skeletal muscle: 639.6 adipose tissue: 342.4 Cell line enriched 5 fHDF/TERT166: 246.0 +RCE1 FACE-2, FACE2, hRCE1, RCE1A, RCE1B ENSG00000173653 Ras converting CAAX endopeptidase 1 11 66842835-66846546 Enzymes, Predicted membrane proteins Evidence at protein level Expressed in all Mixed skin: 23.3 Expressed in all +UQCRH QCR6, UQCR8 ENSG00000173660 Ubiquinol-cytochrome c reductase hinge protein 1 46303631-46316776 Predicted intracellular proteins Evidence at protein level HPA042574 Supported Liver cancer:4.63e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 502.5 Expressed in all +TAS1R1 GPR70, T1R1, TR1 ENSG00000173662 Taste 1 receptor member 1 1 6555181-6579757 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level HPA034579, HPA034580 Approved Mixed Tissue enriched 7 testis: 4.1 gallbladder,skin: 0.5 Cell line enhanced HDLM-2: 1.6;Hep G2: 1.1;LHCN-M2: 1.1 +HES3 bHLHb43 ENSG00000173673 Hes family bHLH transcription factor 3 1 6244192-6245578 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA047927, HPA072697 Uncertain Uncertain Nucleus Tissue enriched Not detected testis: 0.1 Cell line enriched 7 NTERA-2: 11.3 +EIF1AX eIF-1A, eIF-4C, EIF1A, EIF4C ENSG00000173674 Eukaryotic translation initiation factor 1A, X-linked X 20124518-20141844 Predicted intracellular proteins Evidence at protein level HPA002561 Uncertain Approved Approved Cytosol Expressed in all Expressed in all endometrium: 96.3 Expressed in all +SPDYE2B ENSG00000173678 Speedy/RINGO cell cycle regulator family member E2B 7 102650325-102661398 Predicted intracellular proteins Evidence at protein level HPA051750 Supported Not detected Tissue enhanced testis: 3.9 spleen: 2.0 Cell line enhanced Karpas-707: 4.2 +OR1L1 OR1L2, OR9-C ENSG00000173679 Olfactory receptor family 1 subfamily L member 1 9 122661566-122662648 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected urinary bladder: 0.1 Not detected +CXorf23 ENSG00000173681 Chromosome X open reading frame 23 X 19912860-19970298 Predicted intracellular proteins Evidence at protein level HPA027215 Approved Approved Nucleoplasm Lung cancer:5.42e-4 (favourable), Urothelial cancer:5.56e-4 (favourable) Expressed in all Mixed parathyroid gland: 11.8 Expressed in all +PSMD1 P112, Rpn2, S1 ENSG00000173692 Proteasome 26S subunit, non-ATPase 1 2 231056864-231172827 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB021092, HPA036736, HPA036737 Enhanced Approved Nucleoplasm
Actin filaments Liver cancer:8.63e-12 (unfavourable), Lung cancer:2.34e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 204.0 Expressed in all +ADGRG2 EDDM6, GPR64, HE6, TM7LN2 ENSG00000173698 Adhesion G protein-coupled receptor G2 X 18989309-19122637 Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA001478, HPA050029 Enhanced Approved Plasma membrane
Cytosol Tissue enhanced Tissue enriched 6 epididymis: 1494.8 parathyroid gland: 240.0 Cell line enhanced A549: 5.4;BEWO: 7.0;NTERA-2: 6.3;SH-SY5Y: 6.9;U-2197: 13.5 +SPATA3 TSARG1 ENSG00000173699 Spermatogenesis associated 3 2 230996121-231025055 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018254 Enhanced Not detected Tissue enriched 448 testis: 160.1 cerebral cortex: 0.3 Not detected +MUC13 DRCC1 ENSG00000173702 Mucin 13, cell surface associated 3 124905442-124953819 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA045163 Enhanced Renal cancer:9.73e-5 (unfavourable) Tissue enhanced Group enriched 6 colon: 301.8;duodenum: 614.7;rectum: 330.1;small intestine: 555.7 appendix: 79.5 Cell line enhanced A549: 6.6;CACO-2: 5.3;CAPAN-2: 11.9;Karpas-707: 5.6 +SUSD5 KIAA0527 ENSG00000173705 Sushi domain containing 5 3 33150042-33219215 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA052788 Uncertain Uncertain Golgi apparatus
Vesicles Tissue enhanced Mixed cerebral cortex: 11.0 Cell line enhanced BJ hTERT+ SV40 Large T+: 26.7;HUVEC TERT2: 60.2;LHCN-M2: 23.3;TIME: 23.4 +HEG1 HEG, KIAA1237 ENSG00000173706 Heart development protein with EGF like domains 1 3 124965710-125055958 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA010952, HPA011559 Approved Approved Vesicles Renal cancer:1.93e-5 (unfavourable), Urothelial cancer:1.16e-4 (unfavourable) Expressed in all Mixed thyroid gland: 65.0 Cell line enhanced HHSteC: 134.6 +WFIKKN2 WFDC20B, WFIKKNRP ENSG00000173714 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 17 50834650-50842348 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Group enriched Tissue enriched 17 ovary: 76.5 testis: 4.4 Not detected +C11orf80 FLJ22531, TOPOVIBL ENSG00000173715 Chromosome 11 open reading frame 80 11 66744451-66843328 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038932, HPA038933 Approved Approved Centrosome Expressed in all Tissue enhanced skin: 48.2 testis: 26.7 Mixed +TOMM20 KIAA0016, MAS20, MOM19, TOM20 ENSG00000173726 Translocase of outer mitochondrial membrane 20 1 235109336-235128936 Predicted membrane proteins Evidence at protein level CAB005585, HPA011562 Supported Enhanced Mitochondria Expressed in all Expressed in all thyroid gland: 230.8 Expressed in all +C1orf100 ENSG00000173728 Chromosome 1 open reading frame 100 1 244352635-244389663 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 51 testis: 71.1 parathyroid gland: 1.3 Cell line enriched 50 K-562: 4.9 +AGFG1 HRB, RAB, RIP ENSG00000173744 ArfGAP with FG repeats 1 2 227472152-227561214 Predicted intracellular proteins Evidence at protein level HPA008741 Approved Supported Vesicles Liver cancer:7.31e-6 (unfavourable), Ovarian cancer:3.43e-5 (unfavourable), Lung cancer:1.85e-4 (unfavourable), Renal cancer:6.92e-4 (unfavourable), Cervical cancer:7.13e-4 (unfavourable), Glioma:7.89e-4 (favourable) Expressed in all Expressed in all testis: 169.2 Expressed in all +STAT5B ENSG00000173757 Signal transducer and activator of transcription 5B 17 42199168-42276707 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004298, HPA042128, HPA049883, HPA051156 Approved Renal cancer:2.39e-5 (favourable), Pancreatic cancer:1.63e-4 (favourable), Endometrial cancer:9.37e-4 (favourable) Expressed in all Expressed in all endometrium: 71.3 Cell line enhanced HDLM-2: 112.6 +CD7 GP40, LEU-9, Tp40, TP41 ENSG00000173762 CD7 molecule 17 82314868-82317602 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002594, HPA039079 Enhanced Renal cancer:7.75e-11 (unfavourable), Endometrial cancer:2.03e-5 (favourable), Melanoma:2.69e-4 (favourable), Cervical cancer:5.51e-4 (favourable) Expressed in all Tissue enhanced appendix: 43.1;lymph node: 41.5;spleen: 43.1 small intestine: 17.0 Group enriched 5 Hep G2: 35.2;MOLT-4: 95.7 +TOPAZ1 C3orf77, FLJ36157 ENSG00000173769 Testis and ovary specific PAZ domain containing 1 3 44241886-44332098 Predicted intracellular proteins Evidence at protein level HPA047431, HPA051034 Uncertain Not detected Tissue enriched 65 testis: 6.5 all non-specific tissues: 0.0 Not detected +CNP ENSG00000173786 2',3'-cyclic nucleotide 3' phosphodiesterase 17 41966741-41977731 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002672, HPA023266, HPA023278, HPA023280, HPA023338 Enhanced Supported Enhanced Nucleus
Cytosol Expressed in all Tissue enriched 11 cerebral cortex: 614.8 prostate: 54.9 Expressed in all +JUP CTNNG, DP3, DPIII, PDGB, PKGB ENSG00000173801 Junction plakoglobin 17 41754604-41786931 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002139, HPA032047 Supported Enhanced Vesicles
Plasma membrane
Cell Junctions Renal cancer:2.06e-10 (favourable) Expressed in all Group enriched 6 esophagus: 491.8;skin: 785.5 fallopian tube: 113.8 Cell line enhanced HaCaT: 960.4;RT4: 536.8 +HAP1 HAP2, hHLP1, HIP5, HLP ENSG00000173805 Huntingtin associated protein 1 17 41717742-41734644 Predicted intracellular proteins Evidence at protein level HPA023394 Uncertain Pancreatic cancer:4.26e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 11.5;stomach: 12.8 thyroid gland: 6.4 Cell line enriched 8 REH: 87.3 +TDRD12 ECAT8, FLJ13072 ENSG00000173809 Tudor domain containing 12 19 32719753-32829580 Enzymes, Predicted intracellular proteins Evidence at protein level Tissue enriched Group enriched 8 epididymis: 10.9;testis: 33.5 ovary: 2.6 Group enriched 34 HDLM-2: 23.6;NTERA-2: 93.5 +EIF1 A121, EIF-1, EIF1A, ISO1, SUI1 ENSG00000173812 Eukaryotic translation initiation factor 1 17 41688885-41692668 Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:9.45e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 481.3 Expressed in all +ENDOV FLJ35220 ENSG00000173818 Endonuclease V 17 80415165-80438086 Predicted intracellular proteins Evidence at protein level Breast cancer:4.24e-5 (favourable), Colorectal cancer:4.40e-4 (unfavourable) Expressed in all Expressed in all testis: 22.2 Mixed +RNF213 C17orf27, KIAA1554, KIAA1618, MYMY2, NET57 ENSG00000173821 Ring finger protein 213 17 80260866-80398786 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003347, HPA026790 Approved Supported Cytosol Endometrial cancer:4.65e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 65.3 Expressed in all +TIGD3 ENSG00000173825 Tigger transposable element derived 3 11 65354767-65357613 Predicted intracellular proteins Evidence at transcript level HPA040016 Approved Nucleoplasm
Nuclear membrane Mixed Tissue enhanced testis: 3.9 small intestine: 2.3 Cell line enhanced SCLC-21H: 4.6 +KCNH6 erg2, HERG2, Kv11.2 ENSG00000173826 Potassium voltage-gated channel subfamily H member 6 17 63523334-63548977 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Tissue enhanced Tissue enhanced kidney: 6.1;prostate: 5.4;small intestine: 5.5 duodenum: 2.2 Group enriched 6 SCLC-21H: 4.0;SH-SY5Y: 1.4 +MARCH10 FLJ35757, MARCH-X, RNF190 ENSG00000173838 Membrane associated ring-CH-type finger 10 17 62701314-62808344 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023322 Enhanced Approved Plasma membrane
Cytosol Mixed Tissue enriched 7 testis: 144.4 fallopian tube: 20.5 Cell line enhanced BEWO: 2.5;EFO-21: 4.5;SCLC-21H: 9.7 +PLK3 CNK, FNK, PRK ENSG00000173846 Polo like kinase 3 1 44800225-44805990 Enzymes, Predicted intracellular proteins Evidence at protein level HPA060318 Enhanced Renal cancer:1.75e-4 (unfavourable) Expressed in all Mixed gallbladder: 24.3 Mixed +NET1 ARHGEF8, NET1A ENSG00000173848 Neuroepithelial cell transforming 1 10 5412551-5458463 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020068 Uncertain Approved Nucleus
Vesicles Liver cancer:3.87e-5 (unfavourable), Pancreatic cancer:8.27e-4 (unfavourable) Expressed in all Expressed in all rectum: 96.4 Expressed in all +DPY19L1 KIAA0877 ENSG00000173852 Dpy-19 like 1 7 34928876-35038271 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059139 Uncertain Approved Vesicles Pancreatic cancer:2.99e-4 (unfavourable) Expressed in all Expressed in all testis: 69.5 Mixed +PHOSPHO1 ENSG00000173868 Phosphoethanolamine/phosphocholine phosphatase 17 49223362-49230766 Enzymes, Predicted intracellular proteins Evidence at protein level HPA053016, HPA065025 Uncertain Approved Plasma membrane
Actin filaments Mixed Tissue enhanced spleen: 20.4;testis: 41.1 bone marrow: 12.4 Cell line enhanced Daudi: 4.3;EFO-21: 3.6;HDLM-2: 4.0 +ZNF791 FLJ90396 ENSG00000173875 Zinc finger protein 791 19 12610918-12633840 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021537 Uncertain Approved Nucleus Urothelial cancer:1.39e-5 (favourable), Lung cancer:9.07e-4 (favourable) Expressed in all Expressed in all thyroid gland: 25.1 Expressed in all +PHC3 EDR3, FLJ12729, FLJ12967, HPH3 ENSG00000173889 Polyhomeotic homolog 3 3 170086732-170181749 Predicted intracellular proteins Evidence at protein level HPA039162, HPA062031 Approved Supported Nucleus Expressed in all Expressed in all bone marrow: 33.5 Expressed in all +GPR160 GPCR1, GPCR150 ENSG00000173890 G protein-coupled receptor 160 3 170037929-170085403 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA006970 Approved Supported Plasma membrane Renal cancer:4.93e-7 (favourable), Lung cancer:1.21e-4 (favourable), Urothelial cancer:3.61e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 435.1 small intestine: 109.0 Cell line enhanced THP-1: 130.2;U-266/70: 156.8 +CBX2 CDCA6, MGC10561 ENSG00000173894 Chromobox 2 17 79778132-79787983 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023083 Approved Supported Nucleoplasm Mixed Tissue enhanced testis: 14.3 placenta: 3.2 Cell line enhanced REH: 87.4;SK-BR-3: 100.2 +SPTBN2 SCA5 ENSG00000173898 Spectrin beta, non-erythrocytic 2 11 66685248-66729226 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009844, HPA039293, HPA043529 Enhanced Supported Cell Junctions
Cytosol Pancreatic cancer:3.14e-5 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 73.0;skin: 59.3;testis: 48.4 parathyroid gland: 24.6 Cell line enhanced NTERA-2: 49.7;SCLC-21H: 59.4 +GOLIM4 GIMPC, GOLPH4, GPP130, P138 ENSG00000173905 Golgi integral membrane protein 4 3 168008677-168095975 Predicted membrane proteins Evidence at protein level HPA001677, HPA002315 Enhanced Enhanced Golgi apparatus Expressed in all Expressed in all small intestine: 93.8 Mixed +KRT28 KRT25D ENSG00000173908 Keratin 28 17 40792203-40799959 Predicted intracellular proteins Evidence at protein level HPA066890 Supported Tissue enhanced Tissue enhanced breast: 1.0 testis: 0.4 Not detected +RBM4B MGC10871, RBM30, RBM4L, ZCCHC15, ZCCHC21B, ZCRB3B ENSG00000173914 RNA binding motif protein 4B 11 66664998-66677921 Predicted intracellular proteins Evidence at protein level HPA042174, HPA047849 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.02e-4 (unfavourable), Pancreatic cancer:2.10e-4 (favourable), Liver cancer:2.94e-4 (unfavourable) Expressed in all Expressed in all ovary: 36.2 Expressed in all +USMG5 bA792D24.4, DAPIT, MGC14697 ENSG00000173915 Up-regulated during skeletal muscle growth 5 homolog (mouse) 10 103389041-103396466 Predicted membrane proteins Evidence at protein level HPA044798 Supported Mitochondria Expressed in all Expressed in all heart muscle: 554.9 Expressed in all +HOXB2 HOX2, HOX2H ENSG00000173917 Homeobox B2 17 48540894-48544989 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047857 Supported Nucleus Glioma:3.01e-4 (unfavourable) Expressed in all Tissue enhanced epididymis: 56.6 cervix, uterine: 24.4 Cell line enhanced AF22: 58.1;HEK 293: 59.6;HMC-1: 112.4;WM-115: 56.1 +C1QTNF1 CTRP1, FLJ90694, GIP, ZSIG37 ENSG00000173918 C1q and tumor necrosis factor related protein 1 17 79022814-79049788 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025429 Approved Renal cancer:9.09e-9 (unfavourable), Cervical cancer:2.95e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 155.0 seminal vesicle: 65.5 Cell line enhanced ASC diff: 229.1;BJ hTERT+: 66.0;HHSteC: 105.8;U-87 MG: 78.1 +MARCH3 MARCH-III, MGC48332, RNF173 ENSG00000173926 Membrane associated ring-CH-type finger 3 5 126867714-127030808 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043406 Uncertain Supported Vesicles Mixed Mixed testis: 10.9 Cell line enhanced hTEC/SVTERT24-B: 41.0;TIME: 27.2 +SWSAP1 C19orf39, FLJ35119, SWS1AP1, ZSWIM7AP1 ENSG00000173928 SWIM-type zinc finger 7 associated protein 1 19 11374685-11376951 Predicted secreted proteins Evidence at protein level HPA052712 Uncertain Stomach cancer:4.07e-4 (favourable) Expressed in all Mixed thyroid gland: 5.1 Mixed +SLCO4C1 OATP-H, OATP4C1, OATPX, SLC21A20 ENSG00000173930 Solute carrier organic anion transporter family member 4C1 5 102233986-102296549 Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:1.12e-4 (favourable) Tissue enriched Tissue enhanced kidney: 42.4 lung: 11.2 Cell line enhanced Karpas-707: 12.0;RPTEC TERT1: 70.8;U-937: 19.1 +RBM4 LARK, RBM4A, ZCCHC21, ZCRB3A ENSG00000173933 RNA binding motif protein 4 11 66638617-66666682 Predicted intracellular proteins Evidence at protein level HPA042174, HPA047849 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 133.6 Expressed in all +PIFO C1orf88, FLJ23853, pitchfork ENSG00000173947 Primary cilia formation 1 111346288-111353013 Predicted intracellular proteins Evidence at protein level Renal cancer:1.44e-4 (favourable), Pancreatic cancer:2.48e-4 (favourable) Mixed Tissue enriched 6 fallopian tube: 272.5 testis: 43.1 Cell line enhanced RPTEC TERT1: 3.4;RT4: 4.3;T-47d: 3.5;U-87 MG: 3.4 +XXYLT1 C3orf21, FLJ35155 ENSG00000173950 Xyloside xylosyltransferase 1 3 195068279-195271167 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.70e-4 (unfavourable) Expressed in all Mixed placenta: 15.0 Expressed in all +UBXN2A UBXD4 ENSG00000173960 UBX domain protein 2A 2 23927285-24004909 Predicted intracellular proteins Evidence at protein level HPA065482, HPA069096 Supported Approved Centrosome Liver cancer:1.39e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 12.5 Expressed in all +RAX2 ARMD6, CORD11, MGC15631, RAXL1 ENSG00000173976 Retina and anterior neural fold homeobox 2 19 3769089-3772221 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052533 Uncertain Not detected Tissue enhanced parathyroid gland: 1.2 fallopian tube: 0.7 Not detected +LRRC63 RP11-139H14.4 ENSG00000173988 Leucine rich repeat containing 63 13 46211943-46277366 Predicted intracellular proteins Evidence at transcript level HPA039318, HPA039763 Uncertain Approved Golgi apparatus Not detected Group enriched 6 cerebral cortex: 1.1;epididymis: 1.7;testis: 2.4 fallopian tube: 0.3 Cell line enhanced HDLM-2: 1.1 +TCAP CMD1N, LGMD2G, T-cap, TELE, telethonin ENSG00000173991 Titin-cap 17 39664187-39666555 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004591, HPA026477 Enhanced Urothelial cancer:4.55e-4 (favourable) Group enriched Group enriched 18 heart muscle: 2132.6;skeletal muscle: 4963.5 esophagus: 195.0 Cell line enhanced SK-BR-3: 5.6 +CCS ENSG00000173992 Copper chaperone for superoxide dismutase 11 66592821-66606019 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008672, HPA040026, HPA044090 Approved Expressed in all Expressed in all parathyroid gland: 21.7 Expressed in all +NRROS ELLP3030, GARPL1, LRRC33, MGC50789, UNQ3030 ENSG00000174004 Negative regulator of reactive oxygen species 3 196639686-196662004 Predicted membrane proteins Evidence at protein level HPA031586 Uncertain Ovarian cancer:9.63e-4 (unfavourable) Expressed in all Mixed bone marrow: 19.8 Cell line enhanced HMC-1: 93.4;NB-4: 87.0;U-937: 59.2 +CEP19 C3orf34, MGC14126 ENSG00000174007 Centrosomal protein 19 3 196706277-196712293 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047614, HPA071138 Enhanced Supported Centrosome Expressed in all Tissue enhanced testis: 18.0 fallopian tube: 6.6 Mixed +KLHL15 KIAA1677 ENSG00000174010 Kelch like family member 15 X 23983720-24027186 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065730 Uncertain Approved Aggresome
Cytosol Expressed in all Mixed bone marrow: 34.7 Expressed in all +FBXO45 Fbx45 ENSG00000174013 F-box protein 45 3 196568611-196589059 Predicted intracellular proteins Evidence at protein level HPA040730 Uncertain Approved Cytosol Prostate cancer:1.16e-5 (unfavourable), Renal cancer:4.93e-5 (unfavourable), Liver cancer:7.61e-5 (unfavourable), Lung cancer:3.77e-4 (unfavourable) Expressed in all Mixed testis: 22.3 Expressed in all +SPERT CBY2, NURIT ENSG00000174015 Spermatid associated 13 45702311-45714559 Predicted intracellular proteins Evidence at protein level HPA039359, HPA040046 Enhanced Approved Plasma membrane
Cell Junctions Mixed Tissue enriched 178 testis: 49.0 fallopian tube,urinary bladder: 0.2 Not detected +FAM46D CT1.26, CT112, MGC26999 ENSG00000174016 Family with sequence similarity 46 member D X 80335504-80445311 Predicted intracellular proteins Evidence at protein level HPA059362 Uncertain Not detected Tissue enriched 52 testis: 6.2 prostate,thyroid gland: 0.1 Cell line enhanced AN3-CA: 1.0 +GNG5 ENSG00000174021 G protein subunit gamma 5 1 84498325-84506565 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB032623, HPA043651 Approved Liver cancer:3.23e-5 (unfavourable) Expressed in all Expressed in all lung: 133.5 Expressed in all +SLC25A30 ENSG00000174032 Solute carrier family 25 member 30 13 45393316-45418455 Predicted intracellular proteins, Transporters Evidence at protein level HPA045260 Approved Nucleoplasm Renal cancer:9.91e-8 (favourable), Ovarian cancer:3.32e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 46.1 Mixed +C9orf131 MGC41945 ENSG00000174038 Chromosome 9 open reading frame 131 9 35041095-35045991 Predicted intracellular proteins Evidence at transcript level HPA022029 Approved Mitochondria Not detected Tissue enriched 12 testis: 62.1 endometrium: 5.1 Cell line enhanced RT4: 7.4 +CD34 ENSG00000174059 CD34 molecule 1 207880972-207911402 CD markers, Predicted membrane proteins Evidence at protein level CAB000018, HPA036722, HPA036723 Enhanced Approved Nucleus
Plasma membrane
Cell Junctions Head and neck cancer:5.93e-5 (favourable), Renal cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all placenta: 316.6 Group enriched 7 HUVEC TERT2: 53.6;MOLT-4: 53.1 +CTSF CATSF, CLN13 ENSG00000174080 Cathepsin F 11 66563463-66568841 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002141, HPA031431, HPA055610 Approved Approved Vesicles
Plasma membrane
Cytosol Renal cancer:8.92e-7 (favourable) Expressed in all Expressed in all ovary: 140.6 Cell line enhanced SK-MEL-30: 123.6 +MSRB3 DFNB74, DKFZp686C1178, FLJ36866 ENSG00000174099 Methionine sulfoxide reductase B3 12 65278643-65488244 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA014432 Uncertain Renal cancer:8.85e-8 (unfavourable), Urothelial cancer:2.17e-4 (unfavourable), Cervical cancer:3.84e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 181.5 Mixed +LEMD3 MAN1 ENSG00000174106 LEM domain containing 3 12 65169571-65248327 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA025078, HPA076986 Uncertain Supported Nuclear membrane Renal cancer:2.30e-4 (favourable) Expressed in all Expressed in all testis: 28.9 Expressed in all +C16orf91 CCSMST1, gs103, URLC5 ENSG00000174109 Chromosome 16 open reading frame 91 16 1419744-1420800 Predicted membrane proteins Evidence at protein level Renal cancer:1.11e-4 (favourable) Expressed in all Expressed in all adrenal gland: 11.9 Expressed in all +TLR10 CD290 ENSG00000174123 Toll like receptor 10 4 38772239-38782990 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Mixed Group enriched 7 appendix: 21.1;lymph node: 51.7;spleen: 34.7;tonsil: 45.1 urinary bladder: 5.5 Group enriched 65 Daudi: 51.1;REH: 22.0;U-698: 17.6 +TLR1 CD281, KIAA0012, rsc786 ENSG00000174125 Toll like receptor 1 4 38790677-38856817 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Expressed in all Mixed appendix: 37.2 Cell line enhanced Daudi: 8.0;HUVEC TERT2: 10.5;RPMI-8226: 9.8;U-698: 14.4 +TLR6 CD286 ENSG00000174130 Toll like receptor 6 4 38823715-38856817 CD markers, Predicted membrane proteins Evidence at protein level HPA062733 Approved Endoplasmic reticulum Mixed Mixed appendix: 14.0 Cell line enhanced CAPAN-2: 11.7 +FAM174A NS5ATP6, TMEM157, UNQ1912 ENSG00000174132 Family with sequence similarity 174 member A 5 100535305-100586741 Predicted membrane proteins Evidence at protein level HPA019539 Approved Approved Golgi apparatus
Cytosol Glioma:3.85e-6 (unfavourable), Renal cancer:5.48e-4 (favourable) Expressed in all Expressed in all fallopian tube: 51.5 Expressed in all +RGMB DRAGON, FLJ90406 ENSG00000174136 Repulsive guidance molecule family member b 5 98768650-98798643 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA016993 Approved Nucleoplasm Expressed in all Mixed cerebral cortex: 43.6 Cell line enhanced BJ: 267.0;HBF TERT88: 210.1 +FAM53A DNTNP ENSG00000174137 Family with sequence similarity 53 member A 4 1617915-1684302 Predicted intracellular proteins Evidence at protein level HPA036452, HPA058138 Enhanced Uncertain Nucleoplasm Mixed Tissue enhanced testis: 17.5 thyroid gland: 7.8 Cell line enhanced SCLC-21H: 9.1 +NWD2 KIAA1239 ENSG00000174145 NACHT and WD repeat domain containing 2 4 37244220-37449465 Predicted intracellular proteins Evidence at protein level HPA046911 Uncertain Not detected Tissue enhanced cerebral cortex: 6.2;thyroid gland: 1.4 adipose tissue: 0.8 Not detected +CYB561D1 FLJ39035, FLJ44753 ENSG00000174151 Cytochrome b561 family member D1 1 109494052-109502932 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027028 Uncertain Pancreatic cancer:5.16e-6 (favourable), Renal cancer:2.22e-4 (favourable), Head and neck cancer:4.68e-4 (favourable) Expressed in all Mixed skin: 21.4 Expressed in all +GSTA3 ENSG00000174156 Glutathione S-transferase alpha 3 6 52896639-52909685 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004342, HPA048934, HPA053817 Approved Supported Cytosol Mixed Tissue enhanced adrenal gland: 56.1;fallopian tube: 102.0 placenta: 32.1 Not detected +ZDHHC24 ENSG00000174165 Zinc finger DHHC-type containing 24 11 66520637-66546238 Enzymes, Predicted membrane proteins Evidence at protein level HPA016619 Approved Approved Vesicles
Cytosol Glioma:2.39e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 10.9 Expressed in all +TRMT10C FLJ20432, MRPP1, RG9MTD1 ENSG00000174173 TRNA methyltransferase 10C, mitochondrial RNase P subunit 3 101561862-101566446 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036671 Approved Supported Nucleoplasm
Mitochondria Renal cancer:3.32e-5 (favourable), Liver cancer:6.56e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.8 Expressed in all +SELP CD62, CD62P, GMP140, GRMP, PADGEM, PSEL ENSG00000174175 Selectin P 1 169588849-169630193 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002145, HPA002655, HPA005990 Enhanced Head and neck cancer:3.12e-4 (favourable) Mixed Mixed smooth muscle: 20.6 Group enriched 46 EFO-21: 34.2;HEL: 30.9 +CTU2 C16orf84, NCS2 ENSG00000174177 Cytosolic thiouridylase subunit 2 16 88706463-88715386 Predicted intracellular proteins Evidence at protein level HPA041135, HPA041894 Uncertain Supported Mitochondria Liver cancer:5.68e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 10.3 Expressed in all +MGA FLJ12634, KIAA0518, MAD5, MXD5 ENSG00000174197 MGA, MAX dimerization protein 15 41621224-41773081 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA042278, HPA058183 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 16.2 Expressed in all +C12orf66 FLJ32549 ENSG00000174206 Chromosome 12 open reading frame 66 12 64186316-64222296 Predicted intracellular proteins Evidence at protein level HPA046743, HPA052855 Uncertain Enhanced Microtubules
Cytokinetic bridge
Mitotic spindle Expressed in all Expressed in all parathyroid gland: 12.3 Expressed in all +ARL13A ARL13 ENSG00000174225 ADP ribosylation factor like GTPase 13A X 100969708-100990829 Predicted intracellular proteins Evidence at transcript level HPA037377, HPA037378 Uncertain Not detected Tissue enriched 11 testis: 7.6 skin: 0.7 Cell line enhanced CACO-2: 1.8 +SNX31 MGC39715 ENSG00000174226 Sorting nexin 31 8 100572882-100663415 Predicted intracellular proteins, Transporters Evidence at protein level HPA024284, HPA053466 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Testis cancer:1.47e-4 (favourable) Tissue enriched Tissue enhanced urinary bladder: 32.4 esophagus: 7.3 Cell line enriched 51 RT4: 64.7 +PIGG FLJ20265, GPI7, LAS21 ENSG00000174227 Phosphatidylinositol glycan anchor biosynthesis class G 4 499210-540196 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015997 Uncertain Uncertain Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 35.6 Expressed in all +PRPF8 hPrp8, Prp8, PRPC8, RP13, SNRNP220 ENSG00000174231 Pre-mRNA processing factor 8 17 1650629-1684882 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009941, CAB015457 Supported Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 94.4 Expressed in all +ADCY6 AC6 ENSG00000174233 Adenylate cyclase 6 12 48766194-48789037 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB018365 Approved Approved Golgi apparatus Liver cancer:8.23e-4 (unfavourable) Expressed in all Mixed adipose tissue: 44.6 Mixed +REP15 RAB15EP ENSG00000174236 RAB15 effector protein 12 27696519-27697596 Predicted intracellular proteins Evidence at protein level HPA040448, HPA059868 Approved Colorectal cancer:9.43e-5 (favourable) Mixed Tissue enhanced colon: 39.7;rectum: 70.4;stomach: 82.2 small intestine: 39.4 Mixed +PITPNA PITPN, VIB1A ENSG00000174238 Phosphatidylinositol transfer protein alpha 17 1517718-1562816 Predicted intracellular proteins Evidence at protein level HPA000528 Uncertain Approved Vesicles
Cytosol Pancreatic cancer:1.80e-6 (favourable), Endometrial cancer:2.29e-4 (favourable), Renal cancer:9.35e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 117.9 Expressed in all +DDX23 prp28, PRPF28, SNRNP100, U5-100K ENSG00000174243 DEAD-box helicase 23 12 48829764-48852842 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038680, HPA039037 Approved Supported Nucleus
Nucleoli Liver cancer:3.03e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 58.2 Expressed in all +ZNF80 pT17 ENSG00000174255 Zinc finger protein 80 3 114234631-114237578 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA065484 Uncertain Not detected Tissue enhanced breast: 6.4 lymph node: 2.7 Cell line enhanced MCF7: 1.2 +ZNHIT2 C11orf5, FON ENSG00000174276 Zinc finger HIT-type containing 2 11 65116403-65117708 Predicted intracellular proteins Evidence at protein level HPA058066 Uncertain Expressed in all Tissue enhanced testis: 18.9 adrenal gland: 7.7 Mixed +EVX2 ENSG00000174279 Even-skipped homeobox 2 2 176077472-176083913 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA041576 Uncertain Not detected Tissue enhanced prostate: 2.0;seminal vesicle: 2.2;testis: 2.7 cervix, uterine: 1.1 Not detected +ZBTB4 KAISO-L1, KIAA1538, ZNF903 ENSG00000174282 Zinc finger and BTB domain containing 4 17 7459366-7484263 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB008980, HPA064763 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:1.65e-9 (favourable), Pancreatic cancer:2.53e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 84.8 Mixed +TNK1 ENSG00000174292 Tyrosine kinase non receptor 1 17 7380534-7389774 Enzymes, Predicted intracellular proteins Evidence at protein level HPA012065, HPA056452 Uncertain Approved Cell Junctions Urothelial cancer:1.52e-4 (favourable), Endometrial cancer:4.28e-4 (favourable), Renal cancer:6.40e-4 (favourable) Mixed Mixed skin: 5.1 Cell line enhanced HaCaT: 8.0;T-47d: 6.9 +ZHX3 KIAA0395, TIX1 ENSG00000174306 Zinc fingers and homeoboxes 3 20 41178448-41317672 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046498 Supported Nucleoplasm Urothelial cancer:1.84e-5 (unfavourable), Renal cancer:2.53e-5 (favourable), Endometrial cancer:1.62e-4 (unfavourable), Thyroid cancer:7.52e-4 (unfavourable) Expressed in all Expressed in all testis: 43.5 Expressed in all +PHLDA3 TIH1 ENSG00000174307 Pleckstrin homology like domain family A member 3 1 201464383-201469237 Predicted intracellular proteins Evidence at protein level HPA027601 Approved Endometrial cancer:1.77e-4 (favourable), Renal cancer:3.67e-4 (unfavourable) Expressed in all Mixed adipose tissue: 61.5 Cell line enhanced BEWO: 275.2;WM-115: 162.5 +DIRC1 ENSG00000174325 Disrupted in renal carcinoma 1 2 188734155-188790104 Disease related genes, Predicted intracellular proteins Evidence at transcript level HPA068508 Approved Nucleoplasm Not detected Not detected gallbladder: 0.4 Cell line enhanced ASC diff: 2.6;ASC TERT1: 18.9;HSkMC: 7.2 +SLC16A11 FLJ90193, MCT11 ENSG00000174326 Solute carrier family 16 member 11 17 7041630-7043923 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at transcript level Renal cancer:3.19e-7 (favourable), Pancreatic cancer:1.45e-5 (favourable), Liver cancer:2.56e-4 (favourable) Tissue enhanced Tissue enhanced fallopian tube: 8.9;parathyroid gland: 11.0 seminal vesicle: 3.8 Not detected +SLC16A13 MCT13 ENSG00000174327 Solute carrier family 16 member 13 17 7036075-7040121 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA065245 Supported Golgi apparatus Pancreatic cancer:1.50e-4 (favourable) Expressed in all Mixed liver: 15.4 Cell line enhanced A549: 21.3 +GLIS1 FLJ36155 ENSG00000174332 GLIS family zinc finger 1 1 53506237-53738106 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA001409 Uncertain Tissue enhanced Tissue enhanced seminal vesicle: 11.0 prostate: 3.6 Cell line enhanced BJ hTERT+: 3.7;PC-3: 6.7;U-138 MG: 5.0 +OR2Y1 ENSG00000174339 Olfactory receptor family 2 subfamily Y member 1 5 180739042-180740099 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +CHRNA9 NACHRA9 ENSG00000174343 Cholinergic receptor nicotinic alpha 9 subunit 4 40335329-40355217 Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced fallopian tube: 1.1 cerebral cortex,skin: 0.4 Cell line enriched 10 U-87 MG: 15.6 +PODN MGC24995, PCAN, PODOCAN, SLRR5A ENSG00000174348 Podocan 1 53062052-53085502 Predicted intracellular proteins Evidence at protein level Renal cancer:2.02e-5 (unfavourable), Endometrial cancer:1.54e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 161.0 ovary: 107.6 Cell line enhanced BJ: 33.5;fHDF/TERT166: 18.5;HHSteC: 78.9;U-2197: 43.8 +SLC6A19 ENSG00000174358 Solute carrier family 6 member 19 5 1201595-1225117 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA037415, HPA043207 Enhanced Approved Nucleoli Renal cancer:4.14e-6 (favourable) Tissue enhanced Group enriched 21 duodenum: 139.5;kidney: 91.8;small intestine: 156.9 rectum: 6.2 Group enriched 6 BEWO: 13.7;HEL: 16.3 +C11orf45 FLJ43646, MGC35558 ENSG00000174370 Chromosome 11 open reading frame 45 11 128899565-128906035 Predicted secreted proteins Evidence at transcript level HPA039716 Uncertain Approved Cytosol Mixed Mixed skin: 7.5 Cell line enhanced HBEC3-KT: 8.0 +EXO1 HEX1, hExoI ENSG00000174371 Exonuclease 1 1 241847967-241895148 Predicted intracellular proteins Evidence at protein level HPA053079, HPA069738 Enhanced Nucleoplasm
Nuclear bodies Liver cancer:6.94e-7 (unfavourable), Melanoma:2.04e-4 (unfavourable), Endometrial cancer:8.21e-4 (unfavourable) Mixed Mixed bone marrow: 10.7 Mixed +RALGAPA1 DKFZp667F074, GARNL1, GRIPE, KIAA0884, RalGAPalpha1, Tulip1 ENSG00000174373 Ral GTPase activating protein catalytic alpha subunit 1 14 35538352-35809304 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000851 Approved Approved Mitochondria
Cytosol Renal cancer:9.76e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 53.4 Expressed in all +LIG4 ENSG00000174405 DNA ligase 4 13 108207439-108218368 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001334, HPA057325 Supported Supported Nucleoplasm
Cytoplasmic bodies Expressed in all Mixed parathyroid gland: 20.2 Expressed in all +TRHR ENSG00000174417 Thyrotropin releasing hormone receptor 8 109086621-109119584 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA055162 Supported Not detected Not detected thyroid gland: 0.2 Not detected +GTF2IRD2B ENSG00000174428 GTF2I repeat domain containing 2B 7 75092573-75149817 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056679, HPA056680 Approved Nucleoplasm Breast cancer:3.27e-4 (favourable) Mixed Expressed in all ovary: 40.5 Expressed in all +ABRA STARS ENSG00000174429 Actin binding Rho activating protein 8 106759483-106770245 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 9 heart muscle: 11.0;skeletal muscle: 49.8 esophagus: 3.3 Not detected +ATP2A2 ATP2B, DAR, SERCA2 ENSG00000174437 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 12 110280756-110351093 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA062605, HPA067892 Enhanced Supported Nucleoplasm Expressed in all Expressed in all skeletal muscle: 1006.4 Expressed in all +ZWILCH FLJ10036, KNTC1AP ENSG00000174442 Zwilch kinetochore protein 15 66504959-66550128 Predicted intracellular proteins Evidence at protein level Pancreatic cancer:2.90e-5 (unfavourable), Renal cancer:2.58e-4 (unfavourable), Prostate cancer:7.34e-4 (unfavourable) Expressed in all Tissue enriched 7 testis: 97.0 lymph node: 13.5 Expressed in all +RPL4 L4 ENSG00000174444 Ribosomal protein L4 15 66498015-66524532 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA034600 Uncertain Supported Nucleoli
Nuclear bodies
Endoplasmic reticulum
Cytosol Renal cancer:5.20e-5 (unfavourable) Expressed in all Expressed in all ovary: 3692.5 Expressed in all +SNAPC5 SNAP19 ENSG00000174446 Small nuclear RNA activating complex polypeptide 5 15 66490135-66497813 Predicted intracellular proteins Evidence at protein level HPA024379 Uncertain Supported Nucleus Expressed in all Expressed in all testis: 63.7 Expressed in all +STARD6 ENSG00000174448 StAR related lipid transfer domain containing 6 18 54324358-54357964 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 83 testis: 47.5 cerebral cortex,thyroid gland: 0.5 Cell line enhanced HDLM-2: 1.9;Karpas-707: 1.9;U-266/70: 2.5 +GOLGA6L2 CT105, FLJ36144 ENSG00000174450 Golgin A6 family-like 2 15 23439498-23447234 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 110 testis: 39.3 cerebral cortex: 0.3 Cell line enriched 6 U-266/70: 11.4 +VWC2L ENSG00000174453 Von Willebrand factor C domain containing protein 2-like 2 214411065-214578959 Predicted secreted proteins Evidence at protein level HPA044815, HPA059414 Uncertain Not detected Tissue enriched 31 cerebral cortex: 3.1 all non-specific tissues: 0.0 Not detected +C12orf76 FLJ40142 ENSG00000174456 Chromosome 12 open reading frame 76 12 110027028-110073686 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA039713, HPA042013 Uncertain Approved Plasma membrane
Actin filaments Renal cancer:5.74e-5 (unfavourable), Lung cancer:6.44e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 105.7 Expressed in all +ZCCHC12 FLJ16123, PNMA7A, SIZN, SIZN1 ENSG00000174460 Zinc finger CCHC-type containing 12 X 118823790-118826968 Predicted intracellular proteins Evidence at protein level HPA031016, HPA034940 Uncertain Approved Nuclear bodies Thyroid cancer:3.42e-5 (favourable) Tissue enriched Group enriched 8 endometrium: 167.0;fallopian tube: 184.1;smooth muscle: 203.5 cerebral cortex: 24.3 Cell line enhanced HAP1: 4.0;HEK 293: 9.1;NTERA-2: 3.1;SH-SY5Y: 2.6 +CNTNAP2 Caspr2, KIAA0868, NRXN4 ENSG00000174469 Contactin associated protein-like 2 7 146116002-148420998 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA002739 Enhanced Tissue enhanced Group enriched 11 cerebral cortex: 17.9;prostate: 6.0 fallopian tube: 1.0 Cell line enhanced AF22: 7.9;CACO-2: 5.7;NTERA-2: 11.9;SCLC-21H: 28.5 +GALNTL6 GalNAc-T6L, GALNT17 ENSG00000174473 Polypeptide N-acetylgalactosaminyltransferase-like 6 4 171812254-173041559 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031019 Uncertain Not detected Tissue enhanced cerebral cortex: 5.4;testis: 4.5 spleen: 1.9 Not detected +LINGO2 LERN3, LRRN6C ENSG00000174482 Leucine rich repeat and Ig domain containing 2 9 27948078-28670286 Predicted membrane proteins Evidence at transcript level HPA016633, CAB025361 Approved Mixed Tissue enhanced endometrium: 11.9;smooth muscle: 12.9 thyroid gland: 5.0 Cell line enhanced AN3-CA: 2.0;SH-SY5Y: 9.6;WM-115: 4.0 +BBS1 FLJ23590 ENSG00000174483 Bardet-Biedl syndrome 1 11 66510606-66533627 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA058283 Uncertain Uncertain Midbody Mixed Expressed in all parathyroid gland: 65.8 Mixed +DENND4A IRLB, MYCPBP ENSG00000174485 DENN domain containing 4A 15 65658046-65792293 Predicted intracellular proteins Evidence at protein level HPA065343 Uncertain Approved Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 23.8 Expressed in all +IGDCC3 HsT18880, PUNC ENSG00000174498 Immunoglobulin superfamily DCC subclass member 3 15 65327127-65378040 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA015246 Approved Tissue enhanced Group enriched 5 cerebral cortex: 3.3;parathyroid gland: 14.6;placenta: 8.5;testis: 5.0 thyroid gland: 1.5 Cell line enhanced AF22: 103.7;CACO-2: 22.5;Hep G2: 58.8 +GCSAM GCET2, HGAL, MGC40441 ENSG00000174500 Germinal center associated signaling and motility 3 112120841-112133305 Predicted intracellular proteins Evidence at protein level HPA002473 Approved Mixed Tissue enhanced lymph node: 52.0;tonsil: 53.1 skin: 26.2 Group enriched 5 Daudi: 187.5;U-698: 102.8 +ANKRD36C DKFZp667P0924 ENSG00000174501 Ankyrin repeat domain 36C 2 95836919-95991831 Predicted intracellular proteins Evidence at protein level HPA051757, HPA057661 Approved Nucleus
Cytosol Mixed Tissue enhanced testis: 22.0 bone marrow: 10.7 Cell line enhanced PC-3: 28.8 +SLC26A9 ENSG00000174502 Solute carrier family 26 member 9 1 205913048-205943460 Predicted membrane proteins, Transporters Evidence at protein level HPA051485 Enhanced Approved Nucleus
Cell Junctions Head and neck cancer:8.55e-5 (favourable) Tissue enhanced Group enriched 5 lung: 11.4;salivary gland: 31.5;stomach: 30.8 tonsil: 4.8 Group enriched 12 CAPAN-2: 11.8;Hep G2: 3.4 +MFSD4A DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, UNQ3064 ENSG00000174514 Major facilitator superfamily domain containing 4A 1 205568885-205602918 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.27e-13 (favourable), Lung cancer:4.59e-4 (favourable), Cervical cancer:7.54e-4 (favourable) Mixed Tissue enhanced kidney: 75.4;stomach: 111.7 cerebral cortex: 50.6 Cell line enhanced HMC-1: 1.3;SCLC-21H: 1.9 +PELI3 MGC35521 ENSG00000174516 Pellino E3 ubiquitin protein ligase family member 3 11 66466327-66477337 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033750, HPA038875, HPA062281 Uncertain Approved Nucleus
Nucleoli
Vesicles Renal cancer:8.19e-4 (favourable) Expressed in all Mixed parathyroid gland: 23.7 Mixed +TTC9B FLJ30373 ENSG00000174521 Tetratricopeptide repeat domain 9B 19 40216058-40218399 Predicted secreted proteins Evidence at protein level HPA042496 Uncertain Tissue enriched Tissue enriched 67 cerebral cortex: 57.5 adrenal gland: 0.8 Cell line enriched 21 SCLC-21H: 31.6 +MYO1H FLJ37587 ENSG00000174527 Myosin IH 12 109347903-109455523 Predicted intracellular proteins Evidence at protein level HPA039516 Uncertain Not detected Tissue enriched 6 testis: 1.7 thyroid gland: 0.3 Not detected +TMEM81 HC3107, KVLA2788, MGC75217, UNQ2788 ENSG00000174529 Transmembrane protein 81 1 205083129-205084460 Predicted membrane proteins Evidence at protein level HPA052515 Approved Intermediate filaments Renal cancer:6.65e-9 (unfavourable), Liver cancer:3.25e-6 (unfavourable), Urothelial cancer:2.67e-4 (favourable) Expressed in all Mixed testis: 6.7 Expressed in all +MRPL11 ENSG00000174547 Mitochondrial ribosomal protein L11 11 66435075-66466738 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA057685 Approved Supported Mitochondria Expressed in all Expressed in all fallopian tube: 26.7 Expressed in all +KLK15 ACO, HSRNASPH, prostinogen ENSG00000174562 Kallikrein related peptidase 15 19 50825289-50837213 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA019802 Uncertain Tissue enhanced Tissue enhanced colon: 3.2;salivary gland: 2.4 adrenal gland: 1.8 Cell line enriched 5 RPMI-8226: 1.7 +IL20RB DIRS1, FNDC6, IL-20R2, MGC34923 ENSG00000174564 Interleukin 20 receptor subunit beta 3 136946230-137011085 Predicted membrane proteins Evidence at protein level HPA063914 Approved Vesicles
Cytosol Renal cancer:0.00e+0 (unfavourable), Pancreatic cancer:1.44e-4 (unfavourable) Group enriched Group enriched 9 esophagus: 56.6;skin: 165.5 breast: 12.4 Cell line enhanced HaCaT: 70.0;HBEC3-KT: 93.7;HHSteC: 70.6;hTCEpi: 372.4;hTERT-HME1: 73.1 +GOLT1A CGI-141, FLJ42654, GOT1, MGC62027, YMR292W ENSG00000174567 Golgi transport 1A 1 204198160-204214092 Predicted membrane proteins Evidence at protein level Renal cancer:6.35e-5 (unfavourable), Urothelial cancer:1.51e-4 (favourable), Glioma:5.49e-4 (unfavourable) Tissue enriched Tissue enhanced duodenum: 40.3;liver: 79.1;small intestine: 42.3 parathyroid gland: 28.1 Cell line enhanced CACO-2: 12.3;CAPAN-2: 14.9;Hep G2: 14.6;MCF7: 27.7;RT4: 18.6;SK-BR-3: 17.2 +AKIRIN1 C1orf108, FLJ12666 ENSG00000174574 Akirin 1 1 38991223-39006059 Predicted intracellular proteins Evidence at protein level HPA051871 Approved Approved Nucleoplasm
Nuclear membrane Liver cancer:5.39e-7 (unfavourable) Expressed in all Expressed in all testis: 127.9 Expressed in all +NPAS4 bHLHe79, Le-PAS, NXF, PASD10 ENSG00000174576 Neuronal PAS domain protein 4 11 66421004-66426707 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA039255 Uncertain Not detected Tissue enhanced cerebral cortex: 4.1;endometrium: 1.9 smooth muscle: 1.6 Not detected +MSL2 FLJ10546, KIAA1585, msl-2, MSL2L1, RNF184 ENSG00000174579 Male-specific lethal 2 homolog (Drosophila) 3 136148922-136197241 Predicted intracellular proteins Evidence at protein level HPA003413, HPA048482 Uncertain Approved Cytosol Cervical cancer:4.80e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 39.9 Expressed in all +ZNF497 FLJ44773 ENSG00000174586 Zinc finger protein 497 19 58354357-58362848 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047872 Uncertain Approved Nucleus
Cell Junctions Mixed Mixed fallopian tube: 8.1 Cell line enhanced HEK 293: 18.3 +TRAM1L1 MGC26568 ENSG00000174599 Translocation associated membrane protein 1-like 1 4 117083554-117085576 Predicted membrane proteins Evidence at transcript level HPA044560 Uncertain Approved Mitochondria Mixed Mixed cerebral cortex: 14.2 Cell line enhanced SH-SY5Y: 9.5;U-138 MG: 10.8 +CMKLR1 RVER1 ENSG00000174600 Chemerin chemokine-like receptor 1 12 108288044-108339341 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA047865 Uncertain Expressed in all Mixed spleen: 48.4 Group enriched 5 ASC diff: 9.6;ASC TERT1: 41.0;BJ hTERT+: 35.4;LHCN-M2: 11.1 +ANGEL2 Ccr4d, FLJ12793, KIAA0759L ENSG00000174606 Angel homolog 2 1 212992182-213015826 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030796 Uncertain Approved Nucleoplasm
Mitochondria Renal cancer:8.39e-6 (unfavourable), Urothelial cancer:1.20e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 16.0 Expressed in all +UGT8 CGT ENSG00000174607 UDP glycosyltransferase 8 4 114598455-114678224 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014405, HPA065785 Approved Approved Mitochondria Renal cancer:8.55e-5 (favourable) Mixed Tissue enhanced cerebral cortex: 101.0 kidney: 29.8 Cell line enhanced CAPAN-2: 44.4;RPTEC TERT1: 37.0;SCLC-21H: 32.8 +KY FLJ33207 ENSG00000174611 Kyphoscoliosis peptidase 3 134603138-134651636 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036492, HPA036668 Uncertain Approved Nucleoplasm Mixed Tissue enhanced skin: 11.0 parathyroid gland: 9.3 Cell line enhanced Karpas-707: 1.6;U-2197: 2.7;U-87 MG: 8.6 +IQCK FLJ36575, MGC35048 ENSG00000174628 IQ motif containing K 16 19716456-19858467 Predicted intracellular proteins Evidence at transcript level HPA026792, HPA048786 Approved Approved Nuclear speckles
Cytosol Mixed Mixed testis: 33.1 Mixed +SLCO2A1 MATR1, OATP2A1, PGT, SLC21A2 ENSG00000174640 Solute carrier organic anion transporter family member 2A1 3 133932696-134052184 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA013742 Enhanced Liver cancer:9.24e-5 (favourable), Stomach cancer:3.25e-4 (unfavourable), Endometrial cancer:9.69e-4 (favourable) Expressed in all Tissue enhanced seminal vesicle: 114.6 thyroid gland: 71.3 Group enriched 5 EFO-21: 83.6;TIME: 17.5 +ZNF266 HZF1 ENSG00000174652 Zinc finger protein 266 19 9412598-9435578 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026836, HPA054110 Uncertain Enhanced Nucleus
Vesicles
Rods & Rings Head and neck cancer:3.94e-6 (favourable), Pancreatic cancer:3.03e-5 (favourable), Urothelial cancer:9.15e-5 (favourable), Cervical cancer:1.41e-4 (favourable), Renal cancer:1.82e-4 (unfavourable), Lung cancer:4.47e-4 (favourable) Expressed in all Expressed in all epididymis: 117.7 Mixed +OR7D4 hg105, OR19-B, OR7D4P ENSG00000174667 Olfactory receptor family 7 subfamily D member 4 19 9213850-9214871 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.2 Not detected +SLC29A2 DER12, ENT2, HNP36 ENSG00000174669 Solute carrier family 29 member 2 11 66362521-66372214 Predicted membrane proteins, Transporters Evidence at protein level HPA018168 Approved Uncertain Nucleoplasm Endometrial cancer:2.04e-4 (unfavourable), Renal cancer:2.78e-4 (favourable) Expressed in all Tissue enhanced skeletal muscle: 36.4 parathyroid gland: 21.9 Cell line enhanced CAPAN-2: 37.2;T-47d: 48.0 +BRSK2 C11orf7, PEN11B, STK29 ENSG00000174672 BR serine/threonine kinase 2 11 1389899-1462689 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA073690 Approved Golgi apparatus Tissue enhanced Tissue enhanced cerebral cortex: 61.7;pancreas: 19.2 testis: 9.5 Cell line enhanced NTERA-2: 27.4;SCLC-21H: 74.9 +B4GAT1 B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, iGNT ENSG00000174684 Beta-1,4-glucuronyltransferase 1 11 66345372-66347692 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA015484 Uncertain Pancreatic cancer:3.55e-5 (favourable) Expressed in all Tissue enhanced cerebral cortex: 185.2 adrenal gland: 52.4 Expressed in all +TMEM167A FLJ30508, MGC23909, TMEM167 ENSG00000174695 Transmembrane protein 167A 5 83052846-83077863 Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all adrenal gland: 61.9 Expressed in all +LEP OB, OBS ENSG00000174697 Leptin 7 128241284-128257628 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB010490, HPA030721 Approved Approved Tissue enhanced Tissue enriched 11 adipose tissue: 322.5 breast: 29.6 Cell line enhanced BEWO: 2.1 +SH3PXD2B FLJ20831, KIAA1295 ENSG00000174705 SH3 and PX domains 2B 5 172325000-172454523 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036471 Approved Approved Nucleus
Nucleoli fibrillar center Liver cancer:7.51e-5 (unfavourable), Renal cancer:1.90e-4 (unfavourable), Urothelial cancer:8.45e-4 (unfavourable) Expressed in all Mixed cervix, uterine: 35.7 Mixed +KIAA1551 C12orf35, FLJ10652, FLJ20696, UTA2-1 ENSG00000174718 KIAA1551 12 31959370-31993107 Predicted intracellular proteins Evidence at protein level HPA013816, HPA015622 Approved Supported Nucleoli
Intermediate filaments
Cytosol Renal cancer:5.04e-9 (unfavourable) Expressed in all Expressed in all ovary: 90.9 Expressed in all +LARP7 DKFZP564K112, HDCMA18P, PIP7S ENSG00000174720 La ribonucleoprotein domain family member 7 4 112636964-112657592 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026842, HPA027930 Approved Supported Nucleoplasm
Cytosol Urothelial cancer:4.33e-4 (favourable) Expressed in all Expressed in all thyroid gland: 58.5 Expressed in all +FGFBP3 C10orf13, MGC39320 ENSG00000174721 Fibroblast growth factor binding protein 3 10 91906589-91909483 Predicted secreted proteins Evidence at protein level HPA053943 Uncertain Mixed Tissue enriched 8 cerebral cortex: 19.5 thyroid gland: 2.5 Cell line enriched 11 AF22: 312.7 +NR1D2 BD73, EAR-1r, Hs.37288, HZF2, RVR ENSG00000174738 Nuclear receptor subfamily 1 group D member 2 3 23945260-23980618 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053868, HPA054798 Approved Approved Nucleoplasm Renal cancer:4.47e-7 (favourable) Expressed in all Expressed in all thyroid gland: 90.4 Expressed in all +PABPC5 PABP5 ENSG00000174740 Poly(A) binding protein cytoplasmic 5 X 91434595-91438584 Predicted intracellular proteins Evidence at transcript level HPA000164, HPA000165 Approved Mixed Tissue enhanced ovary: 13.4 adrenal gland: 9.6 Cell line enhanced AF22: 6.8;RH-30: 8.1 +BRMS1 DKFZP564A063 ENSG00000174744 Breast cancer metastasis suppressor 1 11 66337333-66345125 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB010824, HPA019637 Approved Approved Centrosome Liver cancer:6.74e-4 (unfavourable) Expressed in all Expressed in all skin: 36.3 Expressed in all +RPL15 EC45, L15, RPL10, RPLY10, RPYL10 ENSG00000174748 Ribosomal protein L15 3 23916545-23923692 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Expressed in all Expressed in all ovary: 3477.9 Expressed in all +C4orf32 FLJ39370 ENSG00000174749 Chromosome 4 open reading frame 32 4 112145397-112195256 Predicted membrane proteins Evidence at protein level HPA062443, HPA069294 Approved Supported Golgi apparatus Stomach cancer:8.87e-4 (unfavourable) Mixed Mixed adipose tissue: 18.6 Cell line enhanced Daudi: 29.7 +HRAS HRAS1 ENSG00000174775 HRas proto-oncogene, GTPase 11 532242-537287 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002015, HPA049830 Approved Liver cancer:2.32e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 25.0 Expressed in all +WDR49 FLJ33620 ENSG00000174776 WD repeat domain 49 3 167478684-167653983 Predicted intracellular proteins Evidence at protein level HPA036225, HPA036226 Uncertain Tissue enhanced Tissue enhanced fallopian tube: 18.4 small intestine: 5.0 Group enriched 17 AF22: 2.8;NTERA-2: 3.2;THP-1: 10.1;U-937: 6.2 +SRP72 ENSG00000174780 Signal recognition particle 72 4 56466915-56503680 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA034621 Approved Liver cancer:3.25e-6 (unfavourable), Colorectal cancer:3.83e-4 (favourable) Expressed in all Expressed in all thyroid gland: 89.0 Expressed in all +PCP2 GPSM4, MGC41903 ENSG00000174788 Purkinje cell protein 2 19 7631611-7633748 Predicted intracellular proteins Evidence at protein level HPA057428 Approved Nuclear speckles
Vesicles Urothelial cancer:2.76e-5 (favourable), Breast cancer:7.93e-4 (favourable) Mixed Tissue enriched 9 testis: 72.6 skin: 8.1 Cell line enhanced HMC-1: 7.2;NB-4: 11.1 +RIN1 ENSG00000174791 Ras and Rab interactor 1 11 66330242-66336840 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA035491 Uncertain Approved Nucleus
Nuclear membrane Renal cancer:9.34e-7 (unfavourable), Endometrial cancer:2.21e-4 (favourable) Expressed in all Tissue enhanced skin: 19.3 cerebral cortex: 5.2 Cell line enhanced U-2197: 58.9 +C4orf26 AI2A4, FLJ23657 ENSG00000174792 Chromosome 4 open reading frame 26 4 75556048-75565885 Disease related genes, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 12 placenta: 5.9 cerebral cortex: 0.5 Cell line enriched 7 HDLM-2: 40.8 +THAP6 MGC30052 ENSG00000174796 THAP domain containing 6 4 75513946-75550473 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035767 Uncertain Approved Nucleus
Centrosome Expressed in all Expressed in all testis: 43.6 Expressed in all +CEP135 CEP4, FLJ13621, KIAA0635 ENSG00000174799 Centrosomal protein 135 4 55948871-56033363 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA073950 Uncertain Focal adhesion sites Urothelial cancer:6.11e-5 (favourable) Mixed Mixed endometrium: 13.0 Expressed in all +FZD4 CD344, EVR1 ENSG00000174804 Frizzled class receptor 4 11 86945679-86955391 CD markers, Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA042328, HPA074833 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:8.60e-5 (favourable) Expressed in all Tissue enhanced adipose tissue: 127.3 seminal vesicle: 42.3 Cell line enhanced ASC diff: 43.7;Hep G2: 57.9;HUVEC TERT2: 78.0;TIME: 37.7 +CD248 CD164L1, TEM1 ENSG00000174807 CD248 molecule 11 66314487-66317044 CD markers, Predicted membrane proteins Evidence at protein level HPA051856 Enhanced Supported Nucleoplasm
Plasma membrane Renal cancer:2.69e-7 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 136.8 placenta: 96.7 Cell line enhanced ASC diff: 336.6;ASC TERT1: 336.4;BJ hTERT+: 268.5;fHDF/TERT166: 348.4;HSkMC: 374.9;U-2197: 735.8 +BTC ENSG00000174808 Betacellulin 4 74744759-74794686 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:6.10e-5 (favourable) Mixed Mixed skin: 15.4 Cell line enhanced CAPAN-2: 13.5;RPTEC TERT1: 6.9 +PDZK1 NHERF3, PDZD1 ENSG00000174827 PDZ domain containing 1 1 145670852-145708148 Predicted intracellular proteins Evidence at protein level HPA005755, HPA006155, CAB008971 Enhanced Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:2.54e-7 (favourable) Group enriched Tissue enhanced kidney: 561.5;small intestine: 127.1 duodenum: 69.0 Cell line enhanced CACO-2: 83.6;RPTEC TERT1: 168.6;T-47d: 547.9 +ADGRE1 EMR1, TM7LN3 ENSG00000174837 Adhesion G protein-coupled receptor E1 19 6887566-6940459 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level HPA052809 Uncertain Mixed Tissue enhanced appendix: 9.9;spleen: 19.7 lung: 6.8 Cell line enhanced BJ hTERT+: 8.5;HDLM-2: 24.5;HMC-1: 15.9;Karpas-707: 16.0 +DENND6A AFI1A, FAM116A, FLJ34969 ENSG00000174839 DENN domain containing 6A 3 57625457-57693089 Predicted intracellular proteins Evidence at protein level HPA062618, HPA069725, HPA071711 Approved Supported Vesicles Renal cancer:7.77e-6 (favourable), Liver cancer:6.36e-4 (unfavourable), Colorectal cancer:9.21e-4 (favourable) Expressed in all Expressed in all ovary: 25.6 Expressed in all +PDE12 2'-PDE, DKFZp667B1218 ENSG00000174840 Phosphodiesterase 12 3 57556276-57566844 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043171 Approved Renal cancer:3.63e-8 (favourable), Colorectal cancer:2.85e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 15.9 Expressed in all +GLMN FAP48, FKBPAP, GLML, GVM, VMGLOM ENSG00000174842 Glomulin, FKBP associated protein 1 92246402-92298987 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031446, HPA031448 Approved Approved Nucleoplasm
Cytosol Renal cancer:5.89e-8 (unfavourable), Liver cancer:2.42e-5 (unfavourable), Colorectal cancer:1.71e-4 (favourable) Expressed in all Mixed testis: 15.0 Expressed in all +DNAH12 DHC3, DLP12, DNAH12L, DNAH7L, Dnahc3, DNHD2, FLJ40427, FLJ44290, hdhc3, HL-19 ENSG00000174844 Dynein axonemal heavy chain 12 3 57293699-57544344 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA037493, HPA058203, HPA061365 Enhanced Tissue enhanced Tissue enhanced fallopian tube: 16.3;testis: 11.1 lung: 2.7 Not detected +YIF1A 54TM, FinGER7, YIF1, YIF1P ENSG00000174851 Yip1 interacting factor homolog A, membrane trafficking protein 11 66284580-66289170 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014840 Approved Supported Golgi apparatus
Vesicles
Microtubule organizing center Urothelial cancer:8.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 62.3 Expressed in all +CNIH2 CNIH-2, Cnil, MGC50896 ENSG00000174871 Cornichon family AMPA receptor auxiliary protein 2 11 66278190-66285301 Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enriched 11 cerebral cortex: 52.9 adrenal gland: 4.6 Cell line enhanced SCLC-21H: 74.6;SH-SY5Y: 31.1 +AMY1B AMY1 ENSG00000174876 Amylase, alpha 1B (salivary) 1 103687415-103696680 Enzymes, Predicted secreted proteins Evidence at protein level HPA045394, HPA045399, HPA046980 Supported Tissue enhanced Tissue enriched 15 salivary gland: 1841.0 cervix, uterine: 126.4 Not detected +NLRP6 CLR11.4, NALP6, PAN3, PYPAF5 ENSG00000174885 NLR family pyrin domain containing 6 11 278365-285359 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043681, HPA048500 Supported Liver cancer:4.23e-5 (favourable) Mixed Group enriched 13 duodenum: 39.4;small intestine: 40.2 appendix: 3.0 Cell line enhanced REH: 1.8;U-266/70: 2.8 +NDUFA11 B14.7 ENSG00000174886 NADH:ubiquinone oxidoreductase subunit A11 19 5891276-5904006 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA072209 Uncertain Mitochondria Endometrial cancer:3.38e-5 (favourable), Cervical cancer:4.54e-5 (favourable) Expressed in all Expressed in all heart muscle: 309.7 Expressed in all +RSRC1 BM-011, MGC12197, SFRS21, SRrp53 ENSG00000174891 Arginine and serine rich coiled-coil 1 3 158105855-158545730 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044792 Enhanced Approved Nuclear speckles Endometrial cancer:7.40e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.0 Expressed in all +CATSPERD MGC39581, TMEM146 ENSG00000174898 Cation channel sperm associated auxiliary subunit delta 19 5720677-5778734 Predicted membrane proteins, Transporters Evidence at protein level HPA024056 Supported Tissue enhanced Tissue enriched 161 testis: 16.0 all non-specific tissues: 0.0 Cell line enriched 58 HEL: 6.9 +PQLC2L C3orf55 ENSG00000174899 PQ loop repeat containing 2 like 3 157543246-157677749 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054395 Uncertain Approved Nucleoplasm
Nuclear bodies Mixed Tissue enhanced adipose tissue: 21.6;thyroid gland: 16.0 breast: 6.1 Cell line enhanced ASC diff: 45.0;ASC TERT1: 25.3;EFO-21: 23.8;LHCN-M2: 28.4 +RAB1B ENSG00000174903 RAB1B, member RAS oncogene family 11 66268533-66277492 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010225, HPA056141 Approved Supported Endoplasmic reticulum
Golgi apparatus Renal cancer:1.09e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 185.0 Expressed in all +OR9G1 OR9G5 ENSG00000174914 Olfactory receptor family 9 subfamily G member 1 11 56700388-56701305 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +PTDSS2 PSS2 ENSG00000174915 Phosphatidylserine synthase 2 11 448268-491399 Enzymes, Predicted membrane proteins Evidence at protein level HPA038928, HPA038929 Approved Liver cancer:5.12e-9 (unfavourable) Expressed in all Expressed in all testis: 25.5 Expressed in all +C19orf70 MIC13, P117, QIL1 ENSG00000174917 Chromosome 19 open reading frame 70 19 5678421-5680896 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042672 Approved Supported Nucleoplasm
Mitochondria Renal cancer:7.60e-5 (favourable) Expressed in all Expressed in all heart muscle: 79.9 Expressed in all +C3orf33 AC3-33, FLJ31139 ENSG00000174928 Chromosome 3 open reading frame 33 3 155762617-155806351 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037663 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:6.48e-7 (favourable) Expressed in all Mixed thyroid gland: 14.4 Mixed +OR5M3 ENSG00000174937 Olfactory receptor family 5 subfamily M member 3 11 56469574-56470497 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +SEZ6L2 FLJ90517, PSK-1 ENSG00000174938 Seizure related 6 homolog like 2 16 29871159-29899547 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA064471 Enhanced Colorectal cancer:1.31e-4 (unfavourable), Glioma:7.27e-4 (unfavourable), Cervical cancer:7.46e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 82.4;parathyroid gland: 58.4 adrenal gland: 30.6 Cell line enhanced EFO-21: 72.2 +ASPHD1 ENSG00000174939 Aspartate beta-hydroxylase domain containing 1 16 29900375-29919864 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045175 Uncertain Pancreatic cancer:7.38e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 53.5 gallbladder: 11.9 Mixed +KCTD13 FKSG86, PDIP1, POLDIP1 ENSG00000174943 Potassium channel tetramerization domain containing 13 16 29905012-29927035 Predicted intracellular proteins Evidence at protein level HPA043524 Enhanced Supported Nucleus
Nuclear bodies Renal cancer:8.17e-4 (unfavourable), Colorectal cancer:8.54e-4 (unfavourable), Pancreatic cancer:9.05e-4 (favourable) Expressed in all Mixed testis: 12.5 Mixed +P2RY14 GPR105, KIAA0001 ENSG00000174944 Purinergic receptor P2Y14 3 151212117-151278467 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level CAB022646 Uncertain Renal cancer:1.72e-5 (unfavourable) Mixed Tissue enhanced placenta: 45.9 esophagus: 23.3 Cell line enriched 77 HMC-1: 60.0 +AMZ1 KIAA1950 ENSG00000174945 Archaelysin family metallopeptidase 1 7 2679522-2775500 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020233 Uncertain Mixed Tissue enhanced cerebral cortex: 4.0 endometrium: 1.5 Cell line enhanced BEWO: 6.7;MCF7: 5.8;T-47d: 26.0 +GPR171 H963 ENSG00000174946 G protein-coupled receptor 171 3 151197832-151203201 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA062429 Approved Mixed Tissue enhanced appendix: 29.8 lymph node: 21.5 Cell line enriched 21 U-266/70: 21.2 +GPR149 IEDA, PGR10 ENSG00000174948 G protein-coupled receptor 149 3 154337672-154429715 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA018020 Uncertain Not detected Tissue enriched 6 seminal vesicle: 2.9 testis: 0.4 Not detected +CD164L2 ENSG00000174950 CD164 molecule like 2 1 27379176-27383380 Predicted membrane proteins Evidence at protein level HPA062915 Enhanced Approved Plasma membrane
Cytosol Head and neck cancer:1.64e-5 (favourable) Mixed Tissue enhanced fallopian tube: 46.3 skin: 10.7 Cell line enhanced CAPAN-2: 3.5;HaCaT: 1.6;HBEC3-KT: 1.4;hTCEpi: 2.0;SK-BR-3: 1.9 +FUT1 H, HSC ENSG00000174951 Fucosyltransferase 1 (H blood group) 19 48748011-48755390 Blood group antigen proteins, Enzymes, Predicted membrane proteins Evidence at protein level Renal cancer:3.99e-4 (favourable) Mixed Mixed stomach: 7.1 Cell line enhanced HEL: 8.6;SCLC-21H: 8.1 +DHX36 DDX36, KIAA1488, MLEL1 ENSG00000174953 DEAH-box helicase 36 3 154272546-154324497 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035399 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all testis: 63.3 Expressed in all +OR5J2 ENSG00000174957 Olfactory receptor family 5 subfamily J member 2 11 56176618-56177556 G-protein coupled receptors, Predicted membrane proteins No evidence HPA059466 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +ZIC4 ENSG00000174963 Zic family member 4 3 147386046-147406860 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at transcript level HPA030194 Uncertain Approved Nucleus
Cytosol Mixed Group enriched 6 cerebral cortex: 4.3;skin: 1.4 skeletal muscle: 0.5 Cell line enhanced AF22: 17.0;SH-SY5Y: 5.5 +OR10AG1 ENSG00000174970 Olfactory receptor family 10 subfamily AG member 1 11 55967558-55968463 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR4S2 OR4S2P, OST725 ENSG00000174982 Olfactory receptor family 4 subfamily S member 2 11 55650904-55651839 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +FBXW8 FBW6, FBW8, FBX29, FBXO29 ENSG00000174989 F-box and WD repeat domain containing 8 12 116910956-117031148 Predicted intracellular proteins Evidence at protein level HPA038850, HPA038851 Enhanced Supported Cytosol Expressed in all Expressed in all thyroid gland: 16.2 Expressed in all +CA5A CA5, CAV, CAVA ENSG00000174990 Carbonic anhydrase 5A 16 87881546-87936529 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enhanced liver: 1.3 bone marrow: 0.8 Cell line enhanced Hep G2: 1.4 +ZG16 hZG16, JCLN, JCLN1, ZG16A ENSG00000174992 Zymogen granule protein 16 16 29778240-29782973 Predicted secreted proteins Evidence at protein level HPA052066, HPA052512 Enhanced Tissue enriched Group enriched 6 colon: 363.4;rectum: 502.4;small intestine: 121.4 duodenum: 57.7 Cell line enhanced SK-BR-3: 1.7 +KLC2 FLJ12387 ENSG00000174996 Kinesin light chain 2 11 66257294-66267860 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040416, HPA040434 Enhanced Supported Nucleoplasm
Plasma membrane
Cytosol Head and neck cancer:3.16e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 63.8 Expressed in all +SLC22A1 OCT1 ENSG00000175003 Solute carrier family 22 member 1 6 160121789-160158718 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA029846 Approved Liver cancer:1.35e-5 (favourable) Tissue enriched Tissue enriched 253 liver: 286.8 gallbladder: 1.1 Not detected +TEX36 bA383C5.1, C10orf122 ENSG00000175018 Testis expressed 36 10 125576522-125683144 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 64 testis: 47.4 smooth muscle: 0.7 Cell line enriched 8 U-2197: 7.9 +CTBP2 ribeye ENSG00000175029 C-terminal binding protein 2 10 124984317-125161170 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023559, HPA023564, CAB031916, HPA044971, CAB079018 Approved Supported Approved Cytosol Renal cancer:1.70e-4 (favourable) Expressed in all Expressed in all thyroid gland: 90.2 Mixed +CHST2 C6ST ENSG00000175040 Carbohydrate sulfotransferase 2 3 143119331-143124014 Predicted membrane proteins Evidence at protein level HPA013620 Supported Golgi apparatus Expressed in all Mixed spleen: 15.2 Cell line enhanced HHSteC: 89.5;HMC-1: 44.1 +ZDHHC14 FLJ20984, NEW1CP ENSG00000175048 Zinc finger DHHC-type containing 14 6 157381133-157678146 Enzymes, Predicted membrane proteins Evidence at protein level HPA046033, HPA063754 Uncertain Approved Nucleoli
Mitochondria Pancreatic cancer:6.93e-4 (favourable) Expressed in all Mixed endometrium: 12.3 Cell line enhanced HDLM-2: 47.1 +ATR FRP1, MEC1, SCKL, SCKL1 ENSG00000175054 ATR serine/threonine kinase 3 142449235-142578826 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054320 Supported Nucleoplasm
Golgi apparatus Pancreatic cancer:1.23e-5 (unfavourable), Liver cancer:8.39e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 15.4 Expressed in all +UBE2C UBCH10 ENSG00000175063 Ubiquitin conjugating enzyme E2 C 20 45812576-45816957 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB011464, HPA034569, CAB035990, HPA054975 Approved Enhanced Plasma membrane
Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:6.24e-6 (unfavourable), Pancreatic cancer:6.91e-4 (unfavourable) Expressed in all Mixed tonsil: 56.9 Mixed +DSG4 CDHF13, LAH ENSG00000175065 Desmoglein 4 18 31376777-31414912 Disease related genes, Predicted membrane proteins Evidence at protein level HPA059456 Supported Not detected Not detected testis: 0.8 Cell line enriched 157 HaCaT: 37.3 +GK5 MGC40579 ENSG00000175066 Glycerol kinase 5 (putative) 3 142157527-142225607 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042606, HPA057998 Approved Approved Nucleoplasm
Cytosol Expressed in all Mixed prostate: 13.6 Expressed in all +VCPIP1 DUBA3, FLJ23132, KIAA1850, VCIP135 ENSG00000175073 Valosin containing protein interacting protein 1 8 66628487-66667217 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023932 Uncertain Approved Plasma membrane Expressed in all Mixed bone marrow: 13.1 Expressed in all +RTP1 MGC35450, Z3CXXC1 ENSG00000175077 Receptor transporter protein 1 3 187197486-187201465 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 1.3 testis: 0.7 Cell line enriched 24 T-47d: 2.4 +DES CMD1I, CSM1, CSM2 ENSG00000175084 Desmin 2 219418377-219426739 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000034, HPA018803 Enhanced Supported Intermediate filaments Renal cancer:5.08e-4 (unfavourable) Expressed in all Tissue enhanced heart muscle: 4151.2;skeletal muscle: 5462.0;smooth muscle: 3601.2 seminal vesicle: 3128.9 Cell line enhanced HSkMC: 50.9;LHCN-M2: 120.4;RH-30: 321.1 +PDIK1L CLIK1L ENSG00000175087 PDLIM1 interacting kinase 1 like 1 26111165-26125543 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA064157 Supported Nucleoplasm Expressed in all Expressed in all thyroid gland: 27.4 Expressed in all +SPSB4 SSB-4 ENSG00000175093 SplA/ryanodine receptor domain and SOCS box containing 4 3 141051402-141148611 Predicted intracellular proteins Evidence at protein level HPA062793 Approved Nucleoplasm
Golgi apparatus Glioma:2.57e-4 (favourable) Group enriched Tissue enhanced cerebral cortex: 1.3;spleen: 1.5;testis: 2.4 pancreas: 1.2 Cell line enhanced AF22: 12.9;NTERA-2: 3.7;RH-30: 4.3;SH-SY5Y: 3.9;U-2 OS: 3.1 +RAG2 ENSG00000175097 Recombination activating 2 11 36575574-36598279 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065704 Approved Nucleoplasm Tissue enriched Tissue enriched 22 thyroid gland: 40.1 testis: 1.8 Group enriched 114 MOLT-4: 37.4;REH: 167.6 +TRAF6 RNF85 ENSG00000175104 TNF receptor associated factor 6 11 36487027-36510272 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004605, HPA019805, HPA020599 Approved Supported Nucleoli
Mitochondria Renal cancer:1.36e-4 (favourable) Expressed in all Expressed in all thyroid gland: 16.2 Expressed in all +ZNF654 FLJ10997, FLJ21142 ENSG00000175105 Zinc finger protein 654 3 88059274-88144665 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036172, HPA036173, HPA049262, HPA077939 Uncertain Supported Nucleoplasm
Microtubules Prostate cancer:9.97e-6 (unfavourable) Expressed in all Mixed testis: 11.8 Expressed in all +TVP23C FAM18B2, MGC8763 ENSG00000175106 Trans-golgi network vesicle protein 23 homolog C 17 15502264-15563595 Predicted membrane proteins Evidence at protein level HPA019585, HPA065603 Uncertain Enhanced Golgi apparatus Mixed Mixed thyroid gland: 10.3 Mixed +MRPS22 C3orf5, GIBT, GK002, MRP-S22 ENSG00000175110 Mitochondrial ribosomal protein S22 3 139005806-139357223 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA006083, HPA007830 Enhanced Supported Mitochondria Endometrial cancer:1.35e-5 (unfavourable), Pancreatic cancer:1.55e-5 (unfavourable), Prostate cancer:1.85e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 69.5 Expressed in all +PACS1 FLJ10209, KIAA1175 ENSG00000175115 Phosphofurin acidic cluster sorting protein 1 11 66070363-66244747 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038914 Approved Approved Microtubules
Cytosol Expressed in all Expressed in all testis: 74.1 Expressed in all +WFDC5 dJ211D12.5, WAP1 ENSG00000175121 WAP four-disulfide core domain 5 20 45109452-45115172 Predicted secreted proteins Evidence at transcript level Renal cancer:2.32e-5 (unfavourable) Tissue enhanced Tissue enriched 35 skin: 468.5 breast: 13.2 Not detected +MARCKSL1 F52, MacMARCKS, MLP, MLP1 ENSG00000175130 MARCKS like 1 1 32333832-32336379 Predicted intracellular proteins Evidence at protein level CAB020787, HPA030528 Approved Supported Nucleoplasm
Actin filaments
Cytosol Liver cancer:1.78e-6 (unfavourable), Renal cancer:1.20e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 315.1 Cell line enhanced AF22: 902.3;NTERA-2: 883.9 +SH3BP5L KIAA1720 ENSG00000175137 SH3 binding domain protein 5 like 1 248810446-248826633 Predicted intracellular proteins Evidence at protein level HPA038067, HPA038068 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all Expressed in all cerebral cortex: 19.7 Expressed in all +OR2T1 OR1-25 ENSG00000175143 Olfactory receptor family 2 subfamily T member 1 1 248405995-248407104 G-protein coupled receptors, Predicted membrane proteins No evidence HPA063064 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +YPEL2 FKSG4 ENSG00000175155 Yippee like 2 17 59331689-59401729 Predicted intracellular proteins Evidence at protein level HPA030501, HPA045621 Uncertain Endometrial cancer:6.73e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 26.2 Cell line enhanced HDLM-2: 26.2 +CADM2 IGSF4D, Necl-3, NECL3, SynCAM2 ENSG00000175161 Cell adhesion molecule 2 3 84958981-86074429 Predicted membrane proteins Evidence at protein level HPA010024 Enhanced Tissue enriched Tissue enriched 14 cerebral cortex: 86.2 seminal vesicle: 6.2 Cell line enhanced AF22: 10.8;AN3-CA: 29.1 +ABO A3GALNT, A3GALT1 ENSG00000175164 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase 9 133250401-133275214 Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced small intestine: 17.9 colon: 7.3 Group enriched 7 A-431: 4.5;CAPAN-2: 18.7;HaCaT: 14.1;K-562: 18.6;RT4: 6.3 +PSMD2 MGC14274, P97, Rpn1, S2, TRAP2 ENSG00000175166 Proteasome 26S subunit, non-ATPase 2 3 184298709-184309054 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045192 Approved Liver cancer:6.63e-7 (unfavourable), Lung cancer:1.55e-4 (unfavourable), Head and neck cancer:9.98e-4 (unfavourable) Expressed in all Expressed in all testis: 163.6 Expressed in all +FAM182B ENSG00000175170 Family with sequence similarity 182 member B 20 25763466-25868225 Predicted intracellular proteins Evidence at transcript level HPA050100 Uncertain Approved Nucleoplasm Tissue enhanced Tissue enhanced testis: 11.8 fallopian tube: 6.7 Cell line enriched 5 SCLC-21H: 15.8 +PPM1E CaMKP-N, KIAA1072, POPX1, PP2CH ENSG00000175175 Protein phosphatase, Mg2+/Mn2+ dependent 1E 17 58755869-58985176 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018462, HPA019263 Approved Approved Nucleus
Nucleoli Tissue enhanced Group enriched 5 adrenal gland: 7.3;cerebral cortex: 20.5;testis: 12.1 fallopian tube: 2.4 Cell line enhanced AF22: 12.1;HAP1: 20.6;SCLC-21H: 10.7;SH-SY5Y: 19.9 +FAM131A C3orf40, MGC21688 ENSG00000175182 Family with sequence similarity 131 member A 3 184335926-184348421 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042800 Uncertain Approved Nucleus
Nucleoli Endometrial cancer:2.22e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 100.5 Mixed +CSRP2 CRP2, LMO5, SmLIM ENSG00000175183 Cysteine and glycine rich protein 2 12 76858715-76879060 Predicted intracellular proteins Evidence at protein level HPA045617 Uncertain Renal cancer:4.48e-5 (unfavourable), Prostate cancer:8.52e-4 (favourable) Expressed in all Mixed placenta: 114.6 Cell line enhanced AF22: 320.2 +INHBC ENSG00000175189 Inhibin beta C subunit 12 57434760-57450828 Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 42 liver: 85.9 testis: 2.0 Cell line enhanced Hep G2: 4.5;Karpas-707: 4.7;RH-30: 3.2;U-266/70: 2.6 +PARL PRO2207, PSARL, PSARL1, RHBDS1 ENSG00000175193 Presenilin associated rhomboid like 3 183829271-183884933 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA019545 Approved Approved Mitochondria Urothelial cancer:9.11e-5 (favourable) Expressed in all Expressed in all epididymis: 71.1 Expressed in all +DDIT3 CHOP, CHOP10, GADD153 ENSG00000175197 DNA damage inducible transcript 3 12 57516588-57520517 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058416, HPA068416 Approved Supported Nucleoplasm Liver cancer:6.55e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 263.6 Expressed in all +PCCA ENSG00000175198 Propionyl-CoA carboxylase alpha subunit 13 100089015-100530437 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041716, HPA047792 Enhanced Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all epididymis: 266.0 Cell line enhanced RPTEC TERT1: 124.8;SCLC-21H: 107.6;U-937: 103.1 +HIGD2B HIGD2BP ENSG00000175202 HIG1 hypoxia inducible domain family member 2B 15 72675783-72686149 Predicted membrane proteins Evidence at protein level HPA019016, HPA042715 Uncertain Supported Mitochondria
Cytosol Not detected Tissue enriched 14 testis: 6.7 epididymis,thyroid gland: 0.4 Not detected +DCTN2 DCTN-50, RBP50 ENSG00000175203 Dynactin subunit 2 12 57530102-57547331 Predicted intracellular proteins Evidence at protein level HPA039715, HPA040040 Enhanced Enhanced Centrosome Liver cancer:1.38e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 163.0 Expressed in all +NPPA ANP, PND ENSG00000175206 Natriuretic peptide A 1 11845709-11848345 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA058269 Enhanced Supported Tissue enriched Tissue enriched 1345 heart muscle: 24003.4 epididymis: 17.8 Cell line enhanced SCLC-21H: 13.6;SH-SY5Y: 11.7 +ZNF408 FLJ12827 ENSG00000175213 Zinc finger protein 408 11 46700818-46705912 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA017892 Uncertain Approved Microtubule organizing center
Cytosol Liver cancer:6.59e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 8.3 Expressed in all +CTDSP2 OS4, PSR2, SCP2 ENSG00000175215 CTD small phosphatase 2 12 57819927-57846739 Enzymes, Predicted intracellular proteins Evidence at protein level HPA052607 Uncertain Uncertain Nucleoplasm Expressed in all Expressed in all lung: 170.1 Cell line enriched 7 RH-30: 1169.3 +CKAP5 ch-TOG, KIAA0097, TOG, TOGp ENSG00000175216 Cytoskeleton associated protein 5 11 46743048-46846308 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039377, HPA040375 Enhanced Supported Nucleoli
Plasma membrane
Centrosome Liver cancer:1.03e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 66.2 Expressed in all +ARHGAP1 CDC42GAP, p50rhoGAP, RhoGAP ENSG00000175220 Rho GTPase activating protein 1 11 46677080-46700615 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004689, HPA008285 Approved Approved Supported Vesicles Liver cancer:2.14e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 116.2 Expressed in all +MED16 DRIP92, THRAP5, TRAP95 ENSG00000175221 Mediator complex subunit 16 19 867630-893218 Predicted intracellular proteins Evidence at protein level HPA030685, HPA046495 Uncertain Approved Nucleoli Renal cancer:1.11e-5 (favourable), Endometrial cancer:5.46e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 28.9 Expressed in all +ATG13 KIAA0652 ENSG00000175224 Autophagy related 13 11 46617527-46674818 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA039350 Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:8.59e-5 (unfavourable) Expressed in all Expressed in all testis: 111.6 Expressed in all +GAL3ST3 GAL3ST2 ENSG00000175229 Galactose-3-O-sulfotransferase 3 11 66041952-66049180 Predicted secreted proteins Evidence at protein level Endometrial cancer:6.53e-6 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 4.3;endometrium: 4.3;smooth muscle: 4.8;thyroid gland: 8.2 seminal vesicle: 2.5 Group enriched 5 NTERA-2: 8.8;SH-SY5Y: 7.6 +C1orf127 FLJ37118 ENSG00000175262 Chromosome 1 open reading frame 127 1 10946471-10982037 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA027654 Uncertain Tissue enriched Tissue enhanced skeletal muscle: 5.7 stomach: 2.1 Cell line enhanced THP-1: 1.7 +CHST1 C6ST, KSGal6ST ENSG00000175264 Carbohydrate sulfotransferase 1 11 45648877-45665622 Enzymes, Predicted secreted proteins Evidence at protein level Renal cancer:4.64e-7 (unfavourable), Liver cancer:3.95e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 49.0;parathyroid gland: 19.1 thyroid gland: 9.9 Cell line enhanced HUVEC TERT2: 11.4;TIME: 10.8;WM-115: 35.6 +GOLGA8A GM88, GOLGIN-67 ENSG00000175265 Golgin A8 family member A 15 34379068-34437466 Predicted intracellular proteins Evidence at transcript level HPA051808 Approved Approved Golgi apparatus
Cytosol Renal cancer:2.16e-6 (unfavourable), Urothelial cancer:5.68e-6 (favourable), Lung cancer:7.58e-4 (favourable) Expressed in all Mixed skin: 41.0 Mixed +VWA3A FLJ40941, FLJ46765 ENSG00000175267 Von Willebrand factor A domain containing 3A 16 22092538-22156966 Predicted intracellular proteins Evidence at protein level HPA041696, HPA042044 Uncertain Endometrial cancer:8.15e-4 (favourable) Tissue enhanced Tissue enhanced fallopian tube: 10.8;testis: 3.3 lung: 2.8 Not detected +TP53I11 PIG11 ENSG00000175274 Tumor protein p53 inducible protein 11 11 44885903-44951306 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059727, HPA061276 Uncertain Supported Endoplasmic reticulum
Golgi apparatus Breast cancer:7.33e-5 (unfavourable), Renal cancer:4.65e-4 (unfavourable), Melanoma:6.12e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 58.4 Cell line enhanced SCLC-21H: 453.7;T-47d: 206.4 +CENPS APITD1, CENP-S, FAAP16, MHF1 ENSG00000175279 Centromere protein S 1 10430443-10442809 Predicted intracellular proteins Evidence at protein level Cervical cancer:1.24e-4 (favourable) Expressed in all Expressed in all testis: 84.5 Expressed in all +DOLK DK1, KIAA1094, TMEM15 ENSG00000175283 Dolichol kinase 9 128945530-128947619 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA066767, HPA068706 Supported Nucleus
Nucleoli Thyroid cancer:6.88e-5 (favourable), Renal cancer:5.53e-4 (favourable) Expressed in all Mixed parathyroid gland: 24.7 Expressed in all +PHYHD1 MGC16638 ENSG00000175287 Phytanoyl-CoA dioxygenase domain containing 1 9 128920895-128942041 Predicted intracellular proteins Evidence at protein level HPA012115 Approved Nuclear speckles Renal cancer:6.38e-10 (favourable) Expressed in all Expressed in all cervix, uterine: 59.9 Cell line enhanced ASC diff: 31.7;BEWO: 49.9;RPTEC TERT1: 59.0 +CATSPER1 CATSPER ENSG00000175294 Cation channel sperm associated 1 11 66016752-66026517 Disease related genes, Predicted membrane proteins Evidence at protein level Mixed Tissue enriched 31 testis: 20.4 lung: 0.6 Cell line enhanced CAPAN-2: 3.8;EFO-21: 3.7;HEL: 2.4;HMC-1: 4.4 +CCNE2 CYCE2 ENSG00000175305 Cyclin E2 8 94879770-94896678 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB007825, CAB019374 Enhanced Head and neck cancer:5.87e-4 (favourable), Lung cancer:8.77e-4 (unfavourable) Mixed Tissue enhanced testis: 25.6 bone marrow: 22.4 Mixed +PHYKPL AGXT2L2, MGC15875 ENSG00000175309 5-phosphohydroxy-L-lysine phospho-lyase 5 178208497-178232791 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036461, HPA063608 Approved Approved Mitochondria Renal cancer:3.82e-5 (unfavourable) Expressed in all Expressed in all rectum: 34.5 Expressed in all +ANKS4B FLJ38819, HARP ENSG00000175311 Ankyrin repeat and sterile alpha motif domain containing 4B 16 21233665-21253845 Predicted intracellular proteins Evidence at protein level HPA043523 Approved Approved Nucleoplasm
Cytosol Group enriched Tissue enhanced duodenum: 9.0;rectum: 7.8;small intestine: 12.9 colon: 6.8 Group enriched 10 CACO-2: 1.1;HDLM-2: 3.2;Hep G2: 5.5 +CST6 ENSG00000175315 Cystatin E/M 11 66011841-66013505 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB019316, HPA044963 Enhanced Approved Plasma membrane
Cytosol Tissue enhanced Tissue enriched 9 skin: 213.2 breast: 24.9 Group enriched 6 A-431: 83.9;CAPAN-2: 228.1 +GRAMD2 ENSG00000175318 GRAM domain containing 2 15 72159807-72197785 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA029435 Uncertain Approved Nucleoli
Nuclear speckles
Cytosol Thyroid cancer:7.01e-4 (unfavourable) Mixed Tissue enhanced epididymis: 43.8;placenta: 69.9 lung: 22.8 Group enriched 15 BEWO: 159.8;SK-BR-3: 56.9 +ZNF519 FLJ36809, HsT2362 ENSG00000175322 Zinc finger protein 519 18 14057457-14132490 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028982 Uncertain Approved Nucleoli Mixed Mixed endometrium: 4.0 Mixed +LSM1 CASM, YJL124C ENSG00000175324 LSM1 homolog, mRNA degradation associated 8 38163321-38176730 Predicted intracellular proteins Evidence at protein level HPA024601 Supported Vesicles
Cytosol Expressed in all Expressed in all placenta: 35.7 Expressed in all +PROP1 ENSG00000175325 PROP paired-like homeobox 1 5 177992235-177996242 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049839 Supported Not detected Not detected all non-specific tissues: 0.0 Not detected +ISX RAXLX ENSG00000175329 Intestine specific homeobox 22 35066136-35087387 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060328 Approved Supported Nucleoplasm
Nuclear bodies Tissue enhanced Group enriched 36 colon: 27.4;duodenum: 37.5;rectum: 28.2;small intestine: 29.7 smooth muscle: 0.8 Group enriched 12 CACO-2: 1.3;Hep G2: 3.1 +BANF1 BAF ENSG00000175334 Barrier to autointegration factor 1 11 66002079-66004149 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032896, HPA039242 Enhanced Supported Nucleoplasm
Cytosol Expressed in all Expressed in all fallopian tube: 240.0 Expressed in all +APOF ENSG00000175336 Apolipoprotein F 12 56360569-56362823 Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 111 liver: 220.1 prostate: 1.9 Cell line enriched 9 Hep G2: 3.0 +CHRNA7 ENSG00000175344 Cholinergic receptor nicotinic alpha 7 subunit 15 31923438-32173018 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA029422, CAB033624 Enhanced Mixed Tissue enhanced adrenal gland: 9.4;small intestine: 10.4 stomach: 6.2 Cell line enhanced AN3-CA: 5.8;RT4: 9.8;SH-SY5Y: 7.1;SK-BR-3: 10.0;U-2 OS: 11.2 +TMEM9B C11orf15 ENSG00000175348 TMEM9 domain family member B 11 8947294-8965011 Predicted membrane proteins Evidence at protein level HPA037784 Uncertain Renal cancer:4.26e-5 (favourable) Expressed in all Expressed in all thyroid gland: 129.7 Expressed in all +NRIP3 C11orf14 ENSG00000175352 Nuclear receptor interacting protein 3 11 8980576-9004049 Predicted intracellular proteins Evidence at protein level HPA040573, HPA058827 Uncertain Approved Cytosol Mixed Tissue enhanced cerebral cortex: 36.5;testis: 55.5 adrenal gland: 13.3 Cell line enhanced HMC-1: 44.7;SiHa: 35.9;U-87 MG: 46.3 +PTPN2 PTPT, TC-PTP, TCELLPTP, TCPTP ENSG00000175354 Protein tyrosine phosphatase, non-receptor type 2 18 12785478-12929643 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015004, HPA046176 Enhanced Enhanced Nucleoplasm Renal cancer:1.20e-8 (unfavourable), Ovarian cancer:1.37e-4 (favourable) Expressed in all Expressed in all lymph node: 52.5 Expressed in all +SCUBE2 Cegb1, Cegf1, FLJ16792 ENSG00000175356 Signal peptide, CUB domain and EGF like domain containing 2 11 9020391-9138114 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA006353, HPA029871 Uncertain Breast cancer:2.41e-4 (favourable) Expressed in all Mixed epididymis: 63.1 Cell line enhanced HAP1: 6.0;SK-MEL-30: 6.6;T-47d: 26.8 +EIF1AD haponin, MGC11102 ENSG00000175376 Eukaryotic translation initiation factor 1A domain containing 11 65996545-66002176 Predicted intracellular proteins Evidence at protein level HPA054991, HPA058735 Uncertain Supported Nucleoplasm
Vesicles Endometrial cancer:3.59e-5 (unfavourable), Liver cancer:8.63e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.9 Expressed in all +SMAD2 JV18-1, MADH2, MADR2 ENSG00000175387 SMAD family member 2 18 47808957-47931146 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level CAB025507, HPA067203, CAB073546 Approved Supported Nucleus
Nucleoli
Cytosol Liver cancer:9.44e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 126.7 Expressed in all +EIF3F eIF3-epsilon, eIF3-p47, eIF3f, EIF3S5 ENSG00000175390 Eukaryotic translation initiation factor 3 subunit F 11 7970251-8001862 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049250 Approved Uncertain Nucleoli
Cytosol Liver cancer:6.86e-4 (unfavourable) Expressed in all Expressed in all ovary: 178.4 Expressed in all +ZNF25 FLJ31890, KOX19, Zfp9 ENSG00000175395 Zinc finger protein 25 10 37949572-37976633 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA030190 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all Mixed cerebral cortex: 26.9 Mixed +OR10P1 OR10P1P, OR10P2P, OR10P3P, OST701 ENSG00000175398 Olfactory receptor family 10 subfamily P member 1 12 55636860-55637854 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected heart muscle: 0.2 Not detected +ARL10 ARL10A ENSG00000175414 ADP ribosylation factor like GTPase 10 5 176365468-176401865 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047044 Approved Mixed Mixed skin: 17.0 Mixed +CLTB Lcb ENSG00000175416 Clathrin light chain B 5 176392455-176416569 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003692, HPA036458 Approved Supported Vesicles
Plasma membrane
Cytosol Renal cancer:7.89e-5 (unfavourable) Expressed in all Expressed in all esophagus: 242.7 Expressed in all +PCSK1 NEC1, PC1, PC3, SPC3 ENSG00000175426 Proprotein convertase subtilisin/kexin type 1 5 96390415-96434143 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048564 Approved Glioma:1.31e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 33.6 adrenal gland: 8.3 Group enriched 6 SCLC-21H: 26.6;U-138 MG: 18.8;U-87 MG: 15.5 +LPL LIPD ENSG00000175445 Lipoprotein lipase 8 19901717-19967258 Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048749 Supported Vesicles Urothelial cancer:6.07e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 976.8 heart muscle: 239.2 Cell line enriched 7 AF22: 363.8 +RFESD ENSG00000175449 Rieske Fe-S domain containing 5 95646754-95684773 Predicted intracellular proteins Evidence at protein level CAB016546 Uncertain Approved Nucleoplasm Mixed Tissue enhanced testis: 22.1 bone marrow: 16.5 Group enriched 5 HEL: 37.0;K-562: 69.7 +CCDC14 DKFZp434L1050, FLJ12892 ENSG00000175455 Coiled-coil domain containing 14 3 123897305-123961408 Predicted intracellular proteins Evidence at protein level HPA035278, HPA035279 Uncertain Enhanced Centrosome Renal cancer:3.50e-8 (unfavourable), Urothelial cancer:2.72e-5 (favourable), Prostate cancer:4.76e-4 (unfavourable), Liver cancer:4.82e-4 (unfavourable), Head and neck cancer:5.27e-4 (favourable) Expressed in all Expressed in all testis: 46.5 Expressed in all +TBC1D10C Carabin, EPI64C, FLJ00332 ENSG00000175463 TBC1 domain family member 10C 11 67403915-67410089 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA069743 Enhanced Approved Nuclear bodies Renal cancer:4.35e-7 (unfavourable), Head and neck cancer:1.86e-5 (favourable), Breast cancer:3.83e-4 (favourable), Cervical cancer:4.20e-4 (favourable) Expressed in all Tissue enhanced lymph node: 45.6;spleen: 37.9 appendix: 22.0 Cell line enhanced MOLT-4: 34.1;NB-4: 32.0;U-937: 16.2 +SART1 Ara1, SNRNP110, Snu66 ENSG00000175467 Squamous cell carcinoma antigen recognized by T-cells 1 11 65961689-65979828 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031188, HPA031189, HPA031190 Supported Enhanced Nuclear speckles
Golgi apparatus Expressed in all Expressed in all spleen: 32.3 Expressed in all +PPP2R2D MDS026 ENSG00000175470 Protein phosphatase 2 regulatory subunit Bdelta 10 131900644-131959834 Predicted intracellular proteins Evidence at protein level HPA042122, HPA042770 Approved Approved Cytosol Colorectal cancer:3.14e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 6.7 Mixed +MCTP1 FLJ22344 ENSG00000175471 Multiple C2 and transmembrane domain containing 1 5 94703741-95284575 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019018 Uncertain Approved Nucleoplasm
Cytosol Mixed Mixed bone marrow: 29.0 Mixed +POLD4 p12, POLDS ENSG00000175482 DNA polymerase delta 4, accessory subunit 11 67350777-67356972 Predicted intracellular proteins Evidence at protein level HPA071529 Uncertain Nucleus
Nucleoli
Mitochondria
Cytosol Expressed in all Expressed in all small intestine: 120.1 Mixed +OR52W1 OR52W1P ENSG00000175485 Olfactory receptor family 52 subfamily W member 1 11 6199146-6200259 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected bone marrow: 0.1 Not detected +LRRC25 FLJ38116, MAPA ENSG00000175489 Leucine rich repeat containing 25 19 18391144-18397617 Predicted membrane proteins Evidence at protein level HPA029459 Approved Testis cancer:6.93e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 30.4;spleen: 40.6 bone marrow: 20.7 Cell line enhanced HMC-1: 1.6;THP-1: 1.2;U-937: 1.1 +DPP10 DPL2, DPPY, DPRP3 ENSG00000175497 Dipeptidyl peptidase like 10 2 114442299-115845752 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048767 Uncertain Approved Nucleus
Vesicles
Cytosol Mixed Group enriched 7 adrenal gland: 14.1;cerebral cortex: 34.7 pancreas: 3.6 Cell line enhanced AF22: 4.1;HAP1: 6.4;HMC-1: 3.8;NTERA-2: 3.7;RT4: 5.3;SCLC-21H: 11.4;SH-SY5Y: 4.1 +CLCF1 BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6 ENSG00000175505 Cardiotrophin-like cytokine factor 1 11 67364168-67374177 Disease related genes, Predicted secreted proteins Evidence at protein level HPA042444 Uncertain Approved Nuclear bodies
Vesicles Expressed in all Tissue enhanced gallbladder: 26.3 endometrium: 21.4 Cell line enhanced SiHa: 56.8 +TSGA10IP FAM161C, FLJ32880 ENSG00000175513 Testis specific 10 interacting protein 11 65945445-65959963 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enriched 26 testis: 5.9 thyroid gland: 0.2 Cell line enhanced NTERA-2: 2.1 +GPR152 PGR5 ENSG00000175514 G protein-coupled receptor 152 11 67451301-67452729 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA035078 Uncertain Not detected Not detected spleen: 0.1 Not detected +UBQLNL MGC20470, MGC26958 ENSG00000175518 Ubiquilin-like 11 5514393-5516705 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 30 testis: 40.2 epididymis: 1.3 Not detected +UBQLN3 TUP-1 ENSG00000175520 Ubiquilin 3 11 5507300-5509985 Predicted intracellular proteins Evidence at protein level HPA020547, HPA062018 Enhanced Not detected Tissue enriched 693 testis: 216.4 epididymis: 0.3 Not detected +PNLIP PL ENSG00000175535 Pancreatic lipase 10 116545931-116567855 Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA062430, HPA062494 Enhanced Tissue enriched Tissue enriched 325 pancreas: 93703.0 ovary: 288.0 Cell line enhanced U-2 OS: 1.3 +LIPT2 ENSG00000175536 Lipoyl(octanoyl) transferase 2 (putative) 11 74491712-74493733 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040249 Approved Approved Vesicles
Centrosome Ovarian cancer:1.63e-4 (favourable) Expressed in all Mixed testis: 14.5 Mixed +KCNE3 HOKPP, MiRP2 ENSG00000175538 Potassium voltage-gated channel subfamily E regulatory subunit 3 11 74454841-74467729 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014849 Approved Liver cancer:2.28e-4 (unfavourable) Expressed in all Mixed duodenum: 70.1 Cell line enhanced CACO-2: 18.7;EFO-21: 19.5;HEL: 61.5;NB-4: 27.5;THP-1: 21.7 +CABP4 CSNB2B ENSG00000175544 Calcium binding protein 4 11 67452406-67460313 Disease related genes, Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced spleen: 10.0 epididymis,placenta: 2.4 Cell line enhanced CAPAN-2: 4.4;HMC-1: 18.9 +ALG10B KCR1 ENSG00000175548 ALG10B, alpha-1,2-glucosyltransferase 12 38316578-38329728 Enzymes, Predicted membrane proteins Evidence at protein level HPA043329, HPA063387 Approved Approved Endoplasmic reticulum Mixed Mixed parathyroid gland: 7.6 Expressed in all +DRAP1 NC2-alpha ENSG00000175550 DR1 associated protein 1 11 65919257-65921561 Predicted intracellular proteins Evidence at protein level HPA006790 Uncertain Approved Cytosol Renal cancer:3.73e-5 (unfavourable), Thyroid cancer:4.96e-5 (favourable) Expressed in all Expressed in all testis: 140.8 Expressed in all +LONRF3 FLJ22612, RNF127 ENSG00000175556 LON peptidase N-terminal domain and ring finger 3 X 118974614-119018355 Predicted intracellular proteins Evidence at protein level HPA050422, HPA061162 Uncertain Approved Nucleus
Plasma membrane Pancreatic cancer:4.32e-4 (unfavourable) Mixed Mixed thyroid gland: 12.6 Cell line enhanced K-562: 11.8;PC-3: 13.4;SiHa: 14.0 +UCP3 SLC25A9 ENSG00000175564 Uncoupling protein 3 11 74000281-74009435 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level CAB010771, HPA072225 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Mixed Tissue enriched 19 skeletal muscle: 71.2 testis: 3.8 Group enriched 5 HDLM-2: 13.8;RH-30: 3.3 +UCP2 BMIQ4, SLC25A8 ENSG00000175567 Uncoupling protein 2 11 73974667-73983307 Predicted intracellular proteins, Transporters Evidence at protein level CAB025583, HPA075202 Approved Supported Mitochondria Renal cancer:7.80e-6 (unfavourable), Cervical cancer:4.65e-5 (favourable) Expressed in all Expressed in all lymph node: 385.7 Cell line enhanced SK-BR-3: 390.7 +C11orf68 BLES03, P5326 ENSG00000175573 Chromosome 11 open reading frame 68 11 65916808-65919117 Predicted intracellular proteins Evidence at protein level HPA045938 Uncertain Approved Nucleus
Nucleoli Renal cancer:5.02e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 49.8 Expressed in all +PAAF1 FLJ11848, Rpn14, WDR71 ENSG00000175575 Proteasomal ATPase associated factor 1 11 73876699-73931124 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039952, HPA040020 Uncertain Approved Nucleus
Cytosol Expressed in all Expressed in all testis: 53.1 Expressed in all +MRPL48 CGI-118 ENSG00000175581 Mitochondrial ribosomal protein L48 11 73787316-73865133 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA040241, HPA040864 Approved Liver cancer:3.30e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.1 Expressed in all +RAB6A RAB6 ENSG00000175582 RAB6A, member RAS oncogene family 11 73675638-73761137 Predicted intracellular proteins Evidence at protein level CAB009936, HPA059131 Approved Approved Golgi apparatus Endometrial cancer:8.18e-5 (unfavourable), Liver cancer:1.34e-4 (unfavourable), Pancreatic cancer:2.24e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 267.9 Expressed in all +P2RY2 P2U ENSG00000175591 Purinergic receptor P2Y2 11 73218298-73236352 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level CAB022642 Uncertain Uncertain Cytosol Pancreatic cancer:2.19e-5 (unfavourable) Mixed Tissue enhanced esophagus: 18.9 skeletal muscle: 14.9 Cell line enhanced HaCaT: 31.0;HL-60: 27.2;THP-1: 53.1 +FOSL1 fra-1 ENSG00000175592 FOS like 1, AP-1 transcription factor subunit 11 65892049-65900573 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004396, HPA066901 Uncertain Enhanced Nucleoplasm Renal cancer:6.40e-6 (unfavourable), Pancreatic cancer:9.26e-5 (unfavourable), Lung cancer:1.95e-4 (unfavourable), Head and neck cancer:2.05e-4 (unfavourable), Glioma:2.46e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 35.6;gallbladder: 51.7 urinary bladder: 26.8 Cell line enhanced PC-3: 759.0;WM-115: 1227.8 +ERCC4 FANCQ, RAD1, XPF ENSG00000175595 ERCC excision repair 4, endonuclease catalytic subunit 16 13920157-13952345 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000156, HPA045828 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Mixed testis: 10.4 Expressed in all +SUGCT C7orf10, DERP13, FLJ11808, ORF19 ENSG00000175600 Succinyl-CoA:glutarate-CoA transferase 7 40134977-40860763 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026698, HPA026704, HPA026705 Enhanced Renal cancer:3.93e-7 (favourable), Urothelial cancer:2.53e-4 (unfavourable) Expressed in all Tissue enhanced kidney: 45.0 liver: 14.6 Cell line enhanced HBEC3-KT: 30.6;LHCN-M2: 21.2 +CCDC85B DIPA ENSG00000175602 Coiled-coil domain containing 85B 11 65890112-65891635 Predicted intracellular proteins Evidence at protein level HPA054415 Uncertain Renal cancer:3.78e-5 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 27.6 adipose tissue: 21.1 Cell line enhanced WM-115: 340.7 +TMEM70 FLJ20533 ENSG00000175606 Transmembrane protein 70 8 73972437-73982783 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA023187, CAB034226 Uncertain Supported Nucleoplasm
Mitochondria Expressed in all Expressed in all skeletal muscle: 30.2 Expressed in all +OR4B1 OST208 ENSG00000175619 Olfactory receptor family 4 subfamily B member 1 11 48216792-48217762 G-protein coupled receptors, Predicted membrane proteins No evidence HPA059443 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +RPS6KB2 KLS, P70-BETA, p70S6Kb, STK14B ENSG00000175634 Ribosomal protein S6 kinase B2 11 67428460-67435408 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010010, CAB019404 Approved Supported Cytosol Renal cancer:2.03e-7 (unfavourable) Expressed in all Expressed in all skin: 65.3 Expressed in all +RMI2 BLAP18, C16orf75, MGC24665 ENSG00000175643 RecQ mediated genome instability 2 16 11249619-11351762 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040995 Uncertain Supported Nuclear speckles
Cytosol Liver cancer:2.77e-5 (unfavourable), Cervical cancer:5.69e-5 (favourable) Expressed in all Mixed lymph node: 36.9 Expressed in all +PRM1 CT94.1 ENSG00000175646 Protamine 1 16 11280836-11281350 Predicted intracellular proteins Evidence at protein level HPA055150 Enhanced Tissue enriched Tissue enriched 5169 testis: 9195.1 small intestine: 1.7 Cell line enhanced NB-4: 1.3;U-2197: 1.4 +TOM1L2 ENSG00000175662 Target of myb1 like 2 membrane trafficking protein 17 17843511-17972422 Predicted intracellular proteins Evidence at protein level HPA022541, HPA023304 Enhanced Supported Golgi apparatus
Intermediate filaments Renal cancer:6.21e-9 (favourable), Head and neck cancer:1.24e-4 (favourable), Pancreatic cancer:1.92e-4 (favourable), Ovarian cancer:2.58e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 110.6 Expressed in all +TEX26 C13orf26, MGC40178 ENSG00000175664 Testis expressed 26 13 30932703-30975502 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 30 testis: 40.7 cervix, uterine: 1.3 Not detected +ZNF77 pT1 ENSG00000175691 Zinc finger protein 77 19 2933218-2944971 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA023397 Uncertain Approved Nucleus
Nucleoli Lung cancer:6.79e-6 (favourable), Endometrial cancer:6.65e-5 (favourable), Cervical cancer:8.49e-4 (favourable) Expressed in all Mixed breast: 5.8 Mixed +GPR156 GABABL, PGR28 ENSG00000175697 G protein-coupled receptor 156 3 120164645-120285094 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA028642, HPA028644 Uncertain Supported Plasma membrane Mixed Tissue enhanced testis: 5.0 fallopian tube: 1.8 Cell line enhanced SiHa: 3.8;U-2 OS: 2.0 +LINC00521 C14orf48 ENSG00000175699 Long intergenic non-protein coding RNA 521 14 93987225-94008863 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 26 testis: 11.9 heart muscle: 0.4 Cell line enhanced U-266/70: 1.0 +LINC00116 NCRNA00116 ENSG00000175701 Long intergenic non-protein coding RNA 116 2 110211529-110245420 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all skeletal muscle: 257.6 Mixed +KDF1 C1orf172, FLJ34633, RP11-344H11.3 ENSG00000175707 Keratinocyte differentiation factor 1 1 26949562-26960406 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028639, HPA068312 Uncertain Supported Nucleoplasm
Cell Junctions
Mitotic spindle Renal cancer:3.04e-13 (favourable), Urothelial cancer:4.40e-4 (favourable) Mixed Mixed epididymis: 24.1 Cell line enhanced A-431: 22.4;BEWO: 20.8;CAPAN-2: 20.7;HaCaT: 19.6;HBEC3-KT: 21.9;hTCEpi: 28.4;SK-BR-3: 19.3 +B3GNTL1 B3GNT8 ENSG00000175711 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 17 82942155-83051810 Predicted intracellular proteins Evidence at protein level HPA023585, HPA024547 Supported Approved Nucleoli Mixed Mixed bone marrow: 5.0 Mixed +RBMXL3 CXorf55, FLJ40249 ENSG00000175718 RNA binding motif protein, X-linked like 3 X 115189427-115192868 Predicted intracellular proteins Evidence at protein level HPA051842 Supported Tissue enriched Tissue enriched 26 testis: 2.5 all non-specific tissues: 0.0 Not detected +MLXIP bHLHe36, KIAA0867, MIR, MONDOA ENSG00000175727 MLX interacting protein 12 122078722-122147347 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA023084 Approved Liver cancer:2.28e-4 (unfavourable), Renal cancer:2.92e-4 (unfavourable) Expressed in all Expressed in all rectum: 24.4 Expressed in all +NR2F1 COUP-TFI, EAR-3, ERBAL3, SVP44, TCFCOUP1, TFCOUP1 ENSG00000175745 Nuclear receptor subfamily 2 group F member 1 5 93583337-93594615 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB019281, HPA058974 Approved Nucleoplasm
Cytosol Urothelial cancer:1.47e-4 (unfavourable), Renal cancer:3.47e-4 (unfavourable) Expressed in all Mixed placenta: 75.6 Cell line enhanced AF22: 228.5;HHSteC: 146.5;PC-3: 180.1 +AURKAIP1 AIP, AKIP, FLJ20608 ENSG00000175756 Aurora kinase A interacting protein 1 1 1373730-1375495 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA031821 Approved Supported Nucleoplasm
Mitochondria Renal cancer:8.11e-4 (favourable) Expressed in all Expressed in all testis: 148.3 Expressed in all +TTLL11 bA244O19.1, C9orf20 ENSG00000175764 Tubulin tyrosine ligase like 11 9 121821928-122093606 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021828 Approved Expressed in all Mixed testis: 21.0 Mixed +EIF4E1B FLJ36951 ENSG00000175766 Eukaryotic translation initiation factor 4E family member 1B 5 176630682-176646641 Predicted intracellular proteins Evidence at transcript level HPA045045 Approved Not detected Tissue enhanced cerebral cortex: 1.6;epididymis: 1.2 testis: 0.3 Cell line enriched 6 T-47d: 3.0 +TOMM5 bA613M10.3, C9orf105, Tom5 ENSG00000175768 Translocase of outer mitochondrial membrane 5 9 37582646-37592642 Predicted intracellular proteins Evidence at protein level HPA048712 Approved Supported Mitochondria Liver cancer:2.09e-4 (unfavourable), Ovarian cancer:2.37e-4 (favourable), Melanoma:5.49e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 98.5 Expressed in all +C15orf53 FLJ35695 ENSG00000175779 Chromosome 15 open reading frame 53 15 38696598-38700038 Predicted intracellular proteins Evidence at transcript level HPA041914 Uncertain Not detected Not detected lung,urinary bladder: 0.1 Group enriched 12 HEL: 2.5;HMC-1: 1.7 +SLC35E3 BLOV1 ENSG00000175782 Solute carrier family 35 member E3 12 68746106-68793964 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at transcript level HPA049403 Uncertain Endometrial cancer:1.78e-4 (favourable) Expressed in all Mixed skin: 6.1 Mixed +PRIMA1 PRIMA ENSG00000175785 Proline rich membrane anchor 1 14 93718298-93788481 Predicted membrane proteins Evidence at protein level HPA046671, HPA060047 Approved Approved Nucleoli
Plasma membrane
Cytosol Renal cancer:2.62e-7 (unfavourable), Endometrial cancer:6.99e-5 (unfavourable) Mixed Mixed smooth muscle: 11.7 Cell line enhanced HAP1: 5.8;SCLC-21H: 11.6;SH-SY5Y: 5.9 +ZNF169 MGC51961 ENSG00000175787 Zinc finger protein 169 9 94259311-94301454 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041769 Uncertain Approved Nuclear speckles
Cytosol Mixed Mixed spleen: 7.7 Mixed +RUVBL1 ECP54, INO80H, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49a ENSG00000175792 RuvB like AAA ATPase 1 3 128064778-128153914 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019947, HPA019948 Enhanced Supported Nucleoplasm
Cytosol Liver cancer:1.21e-8 (unfavourable) Expressed in all Expressed in all fallopian tube: 81.6 Expressed in all +SFN YWHAS ENSG00000175793 Stratifin 1 26863138-26864457 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB006268, HPA011105, CAB040552 Enhanced Supported Cytosol Renal cancer:7.45e-6 (unfavourable), Liver cancer:5.68e-5 (unfavourable), Endometrial cancer:1.92e-4 (favourable), Pancreatic cancer:6.01e-4 (unfavourable) Expressed in all Group enriched 8 esophagus: 1090.0;skin: 1156.7 tonsil: 132.7 Cell line enhanced A-431: 663.2;HaCaT: 1030.0;HBEC3-KT: 1288.5;hTCEpi: 852.9 +MSRA ENSG00000175806 Methionine sulfoxide reductase A 8 10054268-10428891 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023804, HPA053069 Approved Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all kidney: 113.1 Mixed +ZNF645 CT138, FLJ25735, HAKAIL ENSG00000175809 Zinc finger protein 645 X 22272943-22274461 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 141 testis: 14.1 all non-specific tissues: 0.0 Not detected +CCDC168 C13orf40, FLJ40176 ENSG00000175820 Coiled-coil domain containing 168 13 102729369-102759070 Predicted membrane proteins Evidence at protein level HPA048184, HPA058793 Uncertain Not detected Tissue enriched 47 testis: 7.6 epididymis: 0.1 Not detected +CTDNEP1 DULLARD, HSA011916, NET56 ENSG00000175826 CTD nuclear envelope phosphatase 1 17 7243591-7252491 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA037439, HPA066466 Uncertain Supported Lipid droplets Pancreatic cancer:1.81e-4 (favourable), Endometrial cancer:6.45e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 190.1 Expressed in all +ETV4 E1A-F, E1AF, PEA3 ENSG00000175832 ETS variant 4 17 43527844-43579620 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005768 Approved Supported Nucleoli Liver cancer:2.48e-4 (unfavourable), Thyroid cancer:7.60e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 30.3 cerebral cortex: 13.6 Cell line enhanced AN3-CA: 164.6;SK-MEL-30: 152.6 +SWI5 bA395P17.9, C9orf119, SAE3 ENSG00000175854 SWI5 homologous recombination repair protein 9 128275379-128288990 Predicted intracellular proteins Evidence at protein level HPA052032, HPA055472 Approved Supported Nucleoplasm
Cytosol Liver cancer:6.78e-4 (unfavourable), Renal cancer:9.39e-4 (favourable) Expressed in all Expressed in all testis: 129.1 Expressed in all +GAPT C5orf29, FLJ33641 ENSG00000175857 GRB2 binding adaptor protein, transmembrane 5 58491435-58497090 Predicted intracellular proteins Evidence at protein level HPA011070 Uncertain Mixed Tissue enhanced appendix: 38.8;tonsil: 38.8 lymph node: 30.1 Cell line enhanced HEL: 64.1;HL-60: 33.1;NB-4: 27.3;THP-1: 22.7;U-937: 92.5 +BAIAP2 BAP2, IRSp53 ENSG00000175866 BAI1 associated protein 2 17 81035122-81117432 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023310, HPA027421 Enhanced Enhanced Plasma membrane
Cytosol Urothelial cancer:7.58e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 124.7 Mixed +CALCB CALC2, CGRP-II, FLJ30166 ENSG00000175868 Calcitonin related polypeptide beta 11 14904997-15082342 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA059886 Supported Endometrial cancer:3.42e-5 (unfavourable) Tissue enhanced Tissue enriched 46 thyroid gland: 32.6 testis: 0.7 Cell line enhanced HEK 293: 5.4;Karpas-707: 7.5;SH-SY5Y: 3.8;U-266/70: 11.8 +CREG2 ENSG00000175874 Cellular repressor of E1A stimulated genes 2 2 101345551-101387595 Predicted secreted proteins Evidence at protein level HPA038224 Enhanced Mixed Tissue enriched 164 cerebral cortex: 90.9 fallopian tube: 0.5 Cell line enhanced CACO-2: 2.0;HaCaT: 5.6;HeLa: 1.6;PC-3: 2.3 +WBSCR28 MGC26719 ENSG00000175877 Williams-Beuren syndrome chromosome region 28 7 73861159-73865893 Predicted membrane proteins Evidence at transcript level HPA077196 Approved Vesicles Mixed Tissue enriched 99 testis: 36.2 duodenum: 0.3 Cell line enhanced MCF7: 1.2 +HOXD8 HOX4, HOX4E ENSG00000175879 Homeobox D8 2 176129694-176132695 Predicted intracellular proteins, Transcription factors Evidence at transcript level Lung cancer:3.78e-4 (unfavourable) Mixed Tissue enhanced epididymis: 122.0;kidney: 83.6 ovary: 43.1 Cell line enhanced RPTEC TERT1: 56.9 +ZDHHC21 DNZ1, HSPC097 ENSG00000175893 Zinc finger DHHC-type containing 21 9 14611071-14693471 Enzymes, Predicted membrane proteins Evidence at protein level HPA065254 Approved Approved Golgi apparatus
Cytosol Urothelial cancer:9.28e-6 (favourable), Renal cancer:1.29e-4 (favourable) Expressed in all Mixed cerebral cortex: 16.0 Cell line enhanced HEL: 26.6 +TSPEAR C21orf29, DFNB98, MGC11251, TSP-EAR ENSG00000175894 Thrombospondin type laminin G domain and EAR repeats 21 44497892-44711580 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB034203, CAB034204, HPA052995 Approved Mixed Tissue enhanced parathyroid gland: 2.7;testis: 2.6 spleen: 1.9 Cell line enhanced Karpas-707: 8.0;RPMI-8226: 4.6;SH-SY5Y: 4.0;U-266/70: 4.9;U-266/84: 5.1 +PLEKHF2 FLJ13187, PHAFIN2, ZFYVE18 ENSG00000175895 Pleckstrin homology and FYVE domain containing 2 8 95133804-95156684 Predicted intracellular proteins Evidence at protein level HPA024829 Uncertain Renal cancer:1.49e-4 (favourable) Expressed in all Expressed in all lymph node: 62.6 Expressed in all +A2M CPAMD5, FWP007, S863-7 ENSG00000175899 Alpha-2-macroglobulin 12 9067664-9116229 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002265, CAB017621 Supported Expressed in all Expressed in all lung: 1920.7 Cell line enhanced AF22: 726.1;ASC diff: 146.4;Hep G2: 419.1;SK-MEL-30: 170.2 +ARL4D ARF4L ENSG00000175906 ADP ribosylation factor like GTPase 4D 17 43398959-43401137 Predicted intracellular proteins Evidence at protein level HPA060379 Uncertain Approved Golgi apparatus
Vesicles Endometrial cancer:1.16e-5 (favourable), Head and neck cancer:6.66e-4 (unfavourable), Urothelial cancer:9.25e-4 (unfavourable) Expressed in all Mixed thyroid gland: 62.5 Mixed +DOK7 C4orf25, Dok-7, FLJ33718, FLJ39137 ENSG00000175920 Docking protein 7 4 3463311-3494483 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059449, HPA062780 Approved Supported Nucleoplasm
Mitochondria Breast cancer:8.45e-5 (favourable), Urothelial cancer:1.28e-4 (favourable), Endometrial cancer:2.19e-4 (favourable) Tissue enhanced Tissue enhanced fallopian tube: 6.7;heart muscle: 11.1 skeletal muscle: 4.7 Cell line enhanced MCF7: 27.3;RH-30: 6.5;T-47d: 7.4 +LRRN1 FIGLER3 ENSG00000175928 Leucine rich repeat neuronal 1 3 3799437-3847703 Predicted membrane proteins Evidence at protein level HPA011071 Enhanced Mixed Tissue enhanced cerebral cortex: 44.3 parathyroid gland: 18.3 Cell line enhanced AF22: 159.4;CAPAN-2: 50.8;HAP1: 50.2;NTERA-2: 96.1 +UBE2O E2-230K ENSG00000175931 Ubiquitin conjugating enzyme E2 O 17 76389451-76453206 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023605 Uncertain Supported Nucleus
Nuclear bodies Renal cancer:4.34e-9 (unfavourable), Liver cancer:6.84e-8 (unfavourable) Expressed in all Expressed in all cerebral cortex: 36.0 Expressed in all +ORAI3 MGC13024, TMEM142C ENSG00000175938 ORAI calcium release-activated calcium modulator 3 16 30949066-30956461 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA015022 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.87e-5 (unfavourable) Expressed in all Expressed in all prostate: 27.1 Cell line enhanced HHSteC: 79.5 +KLHL38 C8ORFK36 ENSG00000175946 Kelch like family member 38 8 123645527-123652950 Predicted intracellular proteins Evidence at protein level HPA024770, HPA027115 Uncertain Uncertain Nucleoplasm
Vesicles Tissue enhanced Group enriched 15 heart muscle: 35.8;skeletal muscle: 91.2 smooth muscle: 4.3 Cell line enhanced BJ hTERT+: 1.4;SK-BR-3: 2.1;U-2197: 4.6 +UNC119B MGC5139, POC7B ENSG00000175970 Unc-119 lipid binding chaperone B 12 120710435-120723640 Predicted intracellular proteins Evidence at protein level Renal cancer:6.69e-10 (favourable), Pancreatic cancer:1.26e-4 (favourable) Expressed in all Expressed in all fallopian tube: 75.8 Expressed in all +DENND2C dJ1156J9.1, DKFZp686G0351, DKFZp779P1149, FLJ37099, RP5-1156J9.1 ENSG00000175984 DENN domain containing 2C 1 114582848-114670422 Predicted intracellular proteins Evidence at protein level HPA054955 Uncertain Approved Nucleus Mixed Tissue enhanced esophagus: 19.5;skeletal muscle: 14.3;skin: 14.8 testis: 10.0 Cell line enhanced U-2197: 10.9;U-266/70: 19.3 +PLEKHD1 UPF0639 ENSG00000175985 Pleckstrin homology and coiled-coil domain containing D1 14 69484692-69531551 Predicted intracellular proteins Evidence at protein level HPA051875 Uncertain Mixed Tissue enhanced parathyroid gland: 2.8;thyroid gland: 2.7 epididymis: 2.0 Cell line enhanced SK-BR-3: 1.8;T-47d: 2.1 +ASCL3 bHLHa42, HASH3, Sgn1 ENSG00000176009 Achaete-scute family bHLH transcription factor 3 11 8937579-8938211 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA027032 Uncertain Not detected Tissue enriched 15 salivary gland: 3.3 spleen,testis: 0.2 Not detected +TUBB6 HsT1601, MGC4083 ENSG00000176014 Tubulin beta 6 class V 18 12307669-12344320 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043640, HPA046280 Approved Renal cancer:1.22e-7 (unfavourable), Urothelial cancer:9.69e-4 (unfavourable) Expressed in all Expressed in all esophagus: 214.3 Mixed +LYSMD3 FLJ13542 ENSG00000176018 LysM domain containing 3 5 90515611-90529584 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018024 Approved Approved Cytosol Colorectal cancer:3.83e-4 (favourable), Renal cancer:9.25e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 39.7 Expressed in all +AMIGO3 ENSG00000176020 Adhesion molecule with Ig like domain 3 3 49716834-49719695 Predicted membrane proteins Evidence at transcript level Not detected Mixed skeletal muscle: 1.0 Cell line enhanced CACO-2: 1.7;SH-SY5Y: 1.7 +B3GALT6 beta3GalT6 ENSG00000176022 Beta-1,3-galactosyltransferase 6 1 1232265-1235041 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Expressed in all Expressed in all cerebral cortex: 12.0 Expressed in all +ZNF613 FLJ13590 ENSG00000176024 Zinc finger protein 613 19 51927147-51948759 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA026833 Uncertain Approved Nucleoplasm
Vesicles Urothelial cancer:1.92e-6 (favourable) Expressed in all Tissue enhanced prostate: 32.4 placenta: 9.8 Mixed +C11orf16 ENSG00000176029 Chromosome 11 open reading frame 16 11 8920076-8933006 Predicted intracellular proteins Evidence at transcript level Endometrial cancer:3.32e-4 (favourable) Tissue enhanced Tissue enhanced fallopian tube: 20.6;lung: 4.1 testis: 2.5 Not detected +TMPRSS7 ENSG00000176040 Transmembrane protease, serine 7 3 112034843-112081269 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA040630 Uncertain Not detected Tissue enhanced testis: 2.5 fallopian tube: 0.6 Not detected +NUPR1 COM1, p8 ENSG00000176046 Nuclear protein 1, transcriptional regulator 16 28532708-28539174 Predicted intracellular proteins Evidence at protein level HPA053895 Approved Nucleus
Cytosol Expressed in all Tissue enhanced thyroid gland: 512.5 pancreas: 235.5 Cell line enhanced HHSteC: 221.9;hTCEpi: 321.9;SK-MEL-30: 256.2;T-47d: 179.8 +JAKMIP2 JAMIP2, KIAA0555 ENSG00000176049 Janus kinase and microtubule interacting protein 2 5 147585439-147782848 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046929, HPA065023 Approved Supported Golgi apparatus Tissue enriched Tissue enriched 6 cerebral cortex: 32.7 testis: 5.3 Cell line enhanced AF22: 19.7;Karpas-707: 34.1;RH-30: 46.3;SCLC-21H: 26.3 +MBLAC2 DKFZp686P15118, MGC46734 ENSG00000176055 Metallo-beta-lactamase domain containing 2 5 90458203-90474768 Predicted intracellular proteins Evidence at protein level HPA037757, HPA060264 Uncertain Approved Nucleus
Nuclear bodies Expressed in all Mixed parathyroid gland: 18.7 Expressed in all +TPRN C9orf75, DFNB79, FLJ90254 ENSG00000176058 Taperin 9 137191617-137204193 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020899 Uncertain Approved Plasma membrane Renal cancer:5.16e-9 (favourable), Cervical cancer:2.13e-4 (favourable) Expressed in all Expressed in all small intestine: 28.3 Mixed +KCNE5 KCNE1L ENSG00000176076 Potassium voltage-gated channel subfamily E regulatory subunit 5 X 109623700-109625172 Disease related genes, Predicted membrane proteins Evidence at protein level HPA042316 Uncertain Uncertain Cytosol Group enriched Tissue enhanced cerebral cortex: 2.1 adipose tissue: 1.1 Cell line enhanced hTEC/SVTERT24-B: 2.0 +ZNF683 Hobit, MGC33414 ENSG00000176083 Zinc finger protein 683 1 26361634-26374522 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023865 Uncertain Endometrial cancer:2.90e-5 (favourable), Urothelial cancer:3.45e-5 (favourable) Mixed Tissue enriched 11 testis: 78.7 lung: 7.1 Cell line enhanced NB-4: 1.4 +SLC35A4 ENSG00000176087 Solute carrier family 35 member A4 5 140564456-140569103 Predicted membrane proteins, Transporters Evidence at protein level HPA062210 Approved Nucleoplasm Renal cancer:4.56e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 113.2 Mixed +AIM1L CRYBG2, FLJ38020 ENSG00000176092 Absent in melanoma 1-like 1 26321859-26360052 Predicted intracellular proteins Evidence at protein level HPA029629, HPA029631 Uncertain Approved Nucleoplasm Endometrial cancer:5.11e-6 (unfavourable), Pancreatic cancer:3.53e-4 (unfavourable) Mixed Tissue enhanced esophagus: 51.2;skin: 21.5 placenta: 13.7 Cell line enhanced BEWO: 33.9;CACO-2: 36.7;CAPAN-2: 27.8 +IP6K1 IHPK1, KIAA0263 ENSG00000176095 Inositol hexakisphosphate kinase 1 3 49724294-49786542 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040825 Approved Supported Nucleus
Nucleoli fibrillar center
Cytosol Renal cancer:5.77e-5 (favourable), Head and neck cancer:2.08e-4 (favourable), Pancreatic cancer:6.85e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 47.5 Expressed in all +SSNA1 N14, NA14 ENSG00000176101 SS nuclear autoantigen 1 9 137188647-137190370 Predicted intracellular proteins Evidence at protein level Endometrial cancer:8.94e-4 (favourable) Expressed in all Expressed in all testis: 101.1 Expressed in all +CSTF3 CstF-77 ENSG00000176102 Cleavage stimulation factor subunit 3 11 33077188-33162371 Predicted intracellular proteins Evidence at protein level HPA039743, HPA040168 Enhanced Enhanced Nucleoplasm Liver cancer:8.20e-6 (unfavourable), Renal cancer:1.61e-5 (unfavourable), Colorectal cancer:1.63e-4 (favourable) Expressed in all Expressed in all epididymis: 76.3 Expressed in all +YES1 c-yes, HsT441, Yes ENSG00000176105 YES proto-oncogene 1, Src family tyrosine kinase 18 721588-812546 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004370, HPA026480 Approved Supported Plasma membrane
Cytosol Pancreatic cancer:2.46e-4 (unfavourable) Expressed in all Expressed in all placenta: 62.0 Mixed +CHMP6 FLJ11749, VPS20 ENSG00000176108 Charged multivesicular body protein 6 17 80991598-81009517 Predicted intracellular proteins Evidence at protein level HPA023001, HPA024460 Approved Pancreatic cancer:9.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 28.7 Expressed in all +DLEU1 BCMS, BCMS1, DLB1, LEU1, LINC00021, NCRNA00021, XTP6 ENSG00000176124 Deleted in lymphocytic leukemia 1 13 50082171-50723236 Predicted intracellular proteins Evidence at protein level CAB017848, HPA039465 Uncertain Approved Plasma membrane
Cytosol Mixed Mixed testis: 9.3 Expressed in all +UFSP1 UFSP ENSG00000176125 UFM1 specific peptidase 1 (inactive) 7 100888723-100889718 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA027099 Uncertain Expressed in all Mixed adipose tissue: 2.0 Mixed +MC5R ENSG00000176136 Melanocortin 5 receptor 18 13824149-13827323 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA042365 Approved Not detected Tissue enriched 7 epididymis: 3.0 esophagus,testis: 0.4 Cell line enhanced U-138 MG: 1.8 +TMEM39A FLJ10902 ENSG00000176142 Transmembrane protein 39A 3 119429500-119468830 Predicted membrane proteins Evidence at protein level HPA039140 Approved Approved Nucleoplasm
Vesicles Renal cancer:1.00e-5 (unfavourable), Liver cancer:3.26e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 32.3 Expressed in all +TCP11L1 FLJ11336 ENSG00000176148 T-complex 11 like 1 11 33039417-33105943 Predicted intracellular proteins Evidence at protein level HPA005769 Approved Approved Cytosol Renal cancer:1.39e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 20.9 Expressed in all +GPX2 GSHPX-GI ENSG00000176153 Glutathione peroxidase 2 14 64939152-64942905 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA003545 Enhanced Approved Nucleoplasm
Cytosol Head and neck cancer:5.10e-4 (unfavourable) Mixed Tissue enhanced gallbladder: 696.1;rectum: 461.1 stomach: 334.9 Group enriched 20 A549: 930.0;HaCaT: 249.8;Hep G2: 659.7;RT4: 543.6;SCLC-21H: 352.2 +CCDC57 FLJ00130, FLJ23754 ENSG00000176155 Coiled-coil domain containing 57 17 82101460-82212830 Predicted intracellular proteins Evidence at protein level HPA023315, HPA023326, HPA023342, HPA023344 Approved Approved Microtubules
Microtubule organizing center
Cytosol Renal cancer:2.28e-6 (unfavourable), Pancreatic cancer:5.55e-5 (favourable) Expressed in all Expressed in all testis: 16.1 Mixed +HSF5 FLJ40311 ENSG00000176160 Heat shock transcription factor 5 17 58420167-58488384 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063613 Enhanced Not detected Tissue enriched 64 testis: 88.4 lymph node: 1.3 Not detected +FOXG1 BF1, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C, HBF-3, HFK1, HFK2, HFK3, QIN ENSG00000176165 Forkhead box G1 14 28760330-28770277 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enriched Tissue enriched 6 cerebral cortex: 29.6 testis: 5.2 Cell line enhanced HEK 293: 10.3;SCLC-21H: 34.2;U-138 MG: 17.5;U-251 MG: 15.3 +SPHK1 SPHK ENSG00000176170 Sphingosine kinase 1 17 76376584-76387860 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022829, HPA028761 Uncertain Supported Plasma membrane
Cytosol Renal cancer:5.14e-6 (unfavourable) Expressed in all Mixed gallbladder: 19.0 Mixed +BNIP3 Nip3 ENSG00000176171 BCL2 interacting protein 3 10 131966455-131982013 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA003015, CAB011676 Supported Uncertain Cytosol Renal cancer:4.55e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 84.1 Cell line enhanced A-431: 338.9;U-87 MG: 339.6 +ENTHD1 FLJ25421 ENSG00000176177 ENTH domain containing 1 22 39743044-39893864 Predicted intracellular proteins Evidence at protein level HPA019800 Uncertain Tissue enriched Tissue enriched 25 testis: 19.7 lymph node: 0.7 Cell line enhanced SK-MEL-30: 1.7 +MYPOP P42pop ENSG00000176182 Myb related transcription factor, partner of profilin 19 45890020-45902604 Predicted intracellular proteins Evidence at protein level HPA065307 Approved Nucleoplasm Ovarian cancer:8.67e-5 (unfavourable), Liver cancer:1.21e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 10.2 Expressed in all +CIDEA CIDE-A ENSG00000176194 Cell death-inducing DFFA-like effector a 18 12254319-12277595 Disease related genes, Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 13 adipose tissue: 221.8 breast: 17.2 Cell line enriched 8 hTEC/SVTERT24-B: 1.4 +OR11H4 ENSG00000176198 Olfactory receptor family 11 subfamily H member 4 14 20242739-20243820 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA052790 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR4D11 OR4D11P ENSG00000176200 Olfactory receptor family 4 subfamily D member 11 11 59503576-59504511 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +LRRTM4 FLJ12568 ENSG00000176204 Leucine rich repeat transmembrane neuronal 4 2 76747719-77593319 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 9 cerebral cortex: 21.3 epididymis: 2.4 Cell line enriched 7 Karpas-707: 91.1 +ATAD5 C17orf41, ELG1, FLJ12735, FRAG1 ENSG00000176208 ATPase family, AAA domain containing 5 17 30831970-30895869 Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced bone marrow: 7.9 lymph node: 4.3 Mixed +SMIM19 C8orf40 ENSG00000176209 Small integral membrane protein 19 8 42541155-42555193 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011145 Uncertain Renal cancer:1.74e-6 (favourable) Expressed in all Expressed in all thyroid gland: 123.2 Expressed in all +OR11H6 ENSG00000176219 Olfactory receptor family 11 subfamily H member 6 14 20223632-20224805 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF404 ENSG00000176222 Zinc finger protein 404 19 43872363-43901385 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA032014, HPA063607 Uncertain Approved Nucleoli
Intermediate filaments Mixed Mixed epididymis: 11.7 Cell line enriched 6 U-2 OS: 45.7 +RTTN DKFZP434G145 ENSG00000176225 Rotatin 18 70003031-70205945 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041343, HPA041967 Uncertain Expressed in all Mixed testis: 5.2 Mixed +OR4K17 ENSG00000176230 Olfactory receptor family 4 subfamily K member 17 14 20117407-20118438 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR10H4 ENSG00000176231 Olfactory receptor family 10 subfamily H member 4 19 15949008-15949958 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR51B6 ENSG00000176239 Olfactory receptor family 51 subfamily B member 6 11 5351508-5352446 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ACBD7 bA455B2.2, FLJ38219 ENSG00000176244 Acyl-CoA binding domain containing 7 10 15077523-15088776 Predicted intracellular proteins Evidence at protein level HPA043326, HPA062478 Approved Vesicles
Cytosol Mixed Tissue enriched 5 cerebral cortex: 40.5 testis: 7.7 Cell line enhanced MOLT-4: 29.4 +OR4L1 OR4L2P ENSG00000176246 Olfactory receptor family 4 subfamily L member 1 14 20060045-20060983 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ANAPC2 APC2, KIAA1406 ENSG00000176248 Anaphase promoting complex subunit 2 9 137174784-137188549 Predicted intracellular proteins Evidence at protein level CAB018692, HPA066539 Enhanced Enhanced Nucleoplasm Pancreatic cancer:1.07e-7 (favourable), Endometrial cancer:8.91e-5 (favourable), Stomach cancer:2.87e-4 (favourable), Renal cancer:3.67e-4 (favourable) Expressed in all Expressed in all testis: 27.2 Expressed in all +OR4K13 ENSG00000176253 Olfactory receptor family 4 subfamily K member 13 14 20033844-20034760 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +HMGB4 FLJ40388 ENSG00000176256 High mobility group box 4 1 33860475-33864791 Predicted intracellular proteins Evidence at protein level HPA035699 Enhanced Not detected Tissue enriched 936 testis: 93.5 all non-specific tissues: 0.0 Not detected +ZBTB8OS ARCH ENSG00000176261 Zinc finger and BTB domain containing 8 opposite strand 1 32600172-32650903 Predicted intracellular proteins Evidence at protein level HPA046315 Approved Approved Plasma membrane Renal cancer:7.11e-8 (unfavourable), Liver cancer:4.25e-4 (unfavourable), Melanoma:8.56e-4 (unfavourable) Expressed in all Expressed in all epididymis: 43.3 Expressed in all +OR4F21 OR4F21P ENSG00000176269 Olfactory receptor family 4 subfamily F member 21 8 166049-167043 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047705 Uncertain Not detected Not detected testis: 0.2 Cell line enriched 6 BEWO: 1.3 +SLC35G1 C10orf60, FLJ33990, TMEM20 ENSG00000176273 Solute carrier family 35 member G1 10 93893973-93956062 Predicted membrane proteins, Transporters Evidence at protein level Mixed Group enriched 8 duodenum: 86.0;small intestine: 44.8 rectum,testis: 7.8 Mixed +OR4K5 ENSG00000176281 Olfactory receptor family 4 subfamily K member 5 14 19920582-19921659 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF135 pHZ-17, ZNF61, ZNF78L1 ENSG00000176293 Zinc finger protein 135 19 58059239-58086310 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006961 Approved Approved Cytosol Renal cancer:3.93e-5 (favourable) Mixed Mixed parathyroid gland: 25.0 Cell line enhanced T-47d: 6.6 +OR4N2 ENSG00000176294 Olfactory receptor family 4 subfamily N member 2 14 19719015-19828372 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 14 testis: 24.3 cerebral cortex: 1.7 Cell line enhanced U-2 OS: 4.7 +OR4M1 ENSG00000176299 Olfactory receptor family 4 subfamily M member 1 14 19780242-19781357 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA058889 Uncertain Not detected Not detected testis: 0.6 Not detected +FOXR1 DLNB13, FOXN5 ENSG00000176302 Forkhead box R1 11 118971707-118981291 Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enriched Tissue enriched 14 testis: 3.1 thyroid gland: 0.2 Not detected +COX8A COX, COX8, COX8-2, COX8L, VIII, VIII-L ENSG00000176340 Cytochrome c oxidase subunit 8A 11 63974607-63976543 Predicted membrane proteins, Transporters Evidence at protein level HPA055942 Supported Renal cancer:2.51e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 512.4 Expressed in all +TAC4 HK-1, PPT-C, Pptc ENSG00000176358 Tachykinin 4 (hemokinin) 17 49838309-49848017 Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced skin: 2.0 liver: 1.0 Cell line enhanced A549: 2.3;BEWO: 5.7;CACO-2: 2.9 +ZSCAN2 FLJ20595, ZFP29, ZNF854 ENSG00000176371 Zinc finger and SCAN domain containing 2 15 84600986-84627796 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007296, HPA024331 Supported Approved Nucleoplasm
Cytosol Urothelial cancer:4.16e-5 (favourable), Pancreatic cancer:3.52e-4 (favourable), Renal cancer:7.46e-4 (favourable) Expressed in all Expressed in all testis: 13.8 Expressed in all +PRR18 MGC35308 ENSG00000176381 Proline rich 18 6 166305300-166308448 Predicted intracellular proteins Evidence at protein level HPA077250 Enhanced Tissue enhanced Tissue enriched 9 cerebral cortex: 32.6 fallopian tube: 3.4 Group enriched 11 SCLC-21H: 5.0;SH-SY5Y: 2.7 +B3GNT4 B3GN-T4, beta3Gn-T4 ENSG00000176383 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 12 122203543-122208952 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA055261 Uncertain Approved Nucleoli
Mitochondria Renal cancer:3.52e-6 (unfavourable) Mixed Tissue enhanced cerebral cortex: 4.3;skin: 2.9 kidney: 1.9 Cell line enhanced HDLM-2: 4.5;hTCEpi: 4.9;T-47d: 5.0 +CDC26 ANAPC12, APC12, C9orf17 ENSG00000176386 Cell division cycle 26 9 113255835-113275589 Predicted intracellular proteins Evidence at protein level HPA044130 Approved Enhanced Nucleoplasm Liver cancer:1.72e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 62.5 Expressed in all +HSD11B2 SDR9C3 ENSG00000176387 Hydroxysteroid 11-beta dehydrogenase 2 16 67430652-67437553 Disease related genes, Predicted membrane proteins Evidence at protein level CAB032443, HPA042186, HPA056385 Enhanced Approved Vesicles Renal cancer:9.51e-5 (favourable) Expressed in all Tissue enhanced colon: 151.6;kidney: 173.3 salivary gland: 122.5 Cell line enhanced NTERA-2: 11.4;RPMI-8226: 9.6;RT4: 11.0;SCLC-21H: 17.5;SK-BR-3: 10.0 +CRLF3 CREME9, CYTOR4 ENSG00000176390 Cytokine receptor like factor 3 17 30769388-30824776 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007596 Enhanced Supported Plasma membrane
Cytosol Renal cancer:1.31e-7 (unfavourable) Expressed in all Mixed lymph node: 39.3 Expressed in all +RNPEP ENSG00000176393 Arginyl aminopeptidase 1 201982372-202006147 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036074, HPA036075, HPA061487 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all duodenum: 66.5 Expressed in all +EID2 CRI2, EID-2, MGC20452 ENSG00000176396 EP300 interacting inhibitor of differentiation 2 19 39538705-39540333 Predicted intracellular proteins Evidence at protein level HPA045477 Uncertain Supported Nucleoplasm Prostate cancer:8.74e-4 (unfavourable), Colorectal cancer:9.73e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 26.3 Expressed in all +DMRTA1 ENSG00000176399 DMRT like family A1 9 22446841-22455740 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044764, HPA062253 Uncertain Approved Vesicles Renal cancer:1.14e-6 (favourable) Mixed Tissue enhanced parathyroid gland: 6.5 liver: 4.3 Cell line enhanced BJ hTERT+: 5.1 +EID2B EID-3, FLJ38944 ENSG00000176401 EP300 interacting inhibitor of differentiation 2B 19 39530990-39532854 Predicted intracellular proteins Evidence at protein level HPA064185 Approved Pancreatic cancer:2.57e-4 (favourable) Mixed Mixed cerebral cortex: 12.4 Mixed +GJC3 CX30.2, GJE1 ENSG00000176402 Gap junction protein gamma 3 7 99923269-99929620 Predicted membrane proteins, Transporters Evidence at protein level HPA015024 Uncertain Group enriched Tissue enhanced breast: 8.7;prostate: 5.3 testis: 2.7 Cell line enhanced SK-MEL-30: 1.8;U-2197: 1.7 +RIMS2 KIAA0751, OBOE, RAB3IP3, RIM2 ENSG00000176406 Regulating synaptic membrane exocytosis 2 8 103500748-104256094 Predicted intracellular proteins Evidence at protein level HPA046538, HPA066498, CAB079049 Enhanced Supported Approved Plasma membrane
Cytosol Mixed Tissue enhanced adrenal gland: 67.7;cerebral cortex: 45.0 cervix, uterine: 11.5 Cell line enhanced Daudi: 10.2;RT4: 8.0;SCLC-21H: 28.6 +KCMF1 DEBT91, DKFZP434L1021, PCMF, ZZZ1 ENSG00000176407 Potassium channel modulatory factor 1 2 84971093-85059472 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030383, HPA030384 Enhanced Enhanced Nucleoplasm
Cytosol Liver cancer:2.33e-7 (unfavourable), Renal cancer:4.18e-6 (unfavourable), Pancreatic cancer:6.10e-5 (unfavourable) Expressed in all Expressed in all testis: 124.6 Expressed in all +DNAJC30 WBSCR18 ENSG00000176410 DnaJ heat shock protein family (Hsp40) member C30 7 73680969-73683453 Predicted membrane proteins Evidence at protein level HPA017318 Uncertain Supported Renal cancer:4.91e-8 (favourable), Glioma:6.59e-5 (unfavourable) Expressed in all Expressed in all testis: 11.3 Expressed in all +SPRYD4 DKFZp686N0877 ENSG00000176422 SPRY domain containing 4 12 56468567-56479707 Predicted intracellular proteins Evidence at protein level HPA053469 Approved Approved Nucleoplasm Endometrial cancer:8.85e-5 (unfavourable), Lung cancer:4.52e-4 (favourable) Expressed in all Mixed liver: 7.8 Mixed +VPS37D MGC35352, WBSCR24 ENSG00000176428 VPS37D, ESCRT-I subunit 7 73667825-73672112 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040978 Uncertain Approved Vesicles Renal cancer:5.80e-9 (favourable), Pancreatic cancer:2.07e-5 (favourable) Expressed in all Mixed cerebral cortex: 6.3 Cell line enhanced SH-SY5Y: 12.4 +CLEC14A C14orf27 ENSG00000176435 C-type lectin domain family 14 member A 14 38254103-38256369 Predicted membrane proteins Evidence at protein level HPA039468, HPA048119 Uncertain Supported Endoplasmic reticulum
Golgi apparatus Head and neck cancer:4.13e-6 (favourable) Expressed in all Tissue enhanced lung: 76.1 adipose tissue: 40.9 Cell line enhanced fHDF/TERT166: 60.3;HUVEC TERT2: 345.4;TIME: 121.9 +SYNE3 C14orf139, C14orf49, FLJ25605, LINC00341, NCRNA00341, Nesp3, Nesprin-3, NET53 ENSG00000176438 Spectrin repeat containing nuclear envelope family member 3 14 95407266-95475836 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055227, HPA077140 Approved Enhanced Nuclear membrane Mixed Mixed adipose tissue: 14.7 Cell line enhanced ASC diff: 31.9;REH: 31.6 +CLK2 clk2 ENSG00000176444 CDC like kinase 2 1 155262868-155278491 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055366, HPA059507 Approved Enhanced Nucleoplasm
Nuclear bodies Renal cancer:2.95e-9 (unfavourable), Liver cancer:2.82e-4 (unfavourable), Colorectal cancer:3.77e-4 (unfavourable), Urothelial cancer:5.43e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.8 Expressed in all +LPCAT4 AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2 ENSG00000176454 Lysophosphatidylcholine acyltransferase 4 15 34358618-34367278 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030719 Uncertain Liver cancer:9.99e-4 (unfavourable) Expressed in all Mixed rectum: 38.6 Expressed in all +SLCO3A1 OATP-D, OATP3A1, SLC21A11 ENSG00000176463 Solute carrier organic anion transporter family member 3A1 15 91853695-92172435 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA066327 Approved Endometrial cancer:6.57e-6 (unfavourable), Cervical cancer:8.61e-4 (favourable) Expressed in all Mixed parathyroid gland: 27.0 Cell line enhanced CAPAN-2: 55.3;HaCaT: 84.3;HMC-1: 48.5 +ZNF575 FLJ32567 ENSG00000176472 Zinc finger protein 575 19 43525497-43536130 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051865 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all Mixed colon: 4.3 Cell line enhanced MOLT-4: 6.2 +WDR25 C14orf67, MGC4645 ENSG00000176473 WD repeat domain 25 14 100376418-100530303 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003113 Approved Supported Nucleoplasm Renal cancer:3.89e-5 (favourable), Liver cancer:7.36e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 13.6 Mixed +SGF29 CCDC101, FLJ32446, TDRD29 ENSG00000176476 SAGA complex associated factor 29 16 28553915-28591790 Predicted intracellular proteins Evidence at protein level HPA052590, HPA053608 Enhanced Approved Nucleus
Nucleoli Pancreatic cancer:2.99e-4 (favourable), Lung cancer:3.37e-4 (favourable), Cervical cancer:4.77e-4 (favourable) Expressed in all Expressed in all testis: 41.6 Expressed in all +PLA2G16 AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754. ENSG00000176485 Phospholipase A2 group XVI 11 63573195-63616883 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level HPA058997 Uncertain Approved Mitochondria Pancreatic cancer:5.58e-6 (unfavourable), Thyroid cancer:2.54e-5 (favourable) Expressed in all Expressed in all adipose tissue: 327.7 Cell line enhanced CAPAN-2: 206.7 +DIRAS1 Di-Ras1, GBTS1, RIG ENSG00000176490 DIRAS family GTPase 1 19 2714567-2721418 Predicted intracellular proteins Evidence at protein level Pancreatic cancer:4.78e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 70.9;heart muscle: 42.5 parathyroid gland: 23.9 Cell line enhanced HMC-1: 37.7;REH: 44.4 +OR5AN1 ENSG00000176495 Olfactory receptor family 5 subfamily AN member 1 11 59364412-59365448 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +PHLDB3 FLJ40193 ENSG00000176531 Pleckstrin homology like domain family B member 3 19 43474954-43504935 Predicted intracellular proteins Evidence at protein level HPA043425 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Pancreatic cancer:6.36e-6 (favourable), Renal cancer:4.11e-5 (unfavourable), Stomach cancer:5.77e-4 (unfavourable) Expressed in all Mixed testis: 24.6 Mixed +PRR15 ENSG00000176532 Proline rich 15 7 29563811-29567295 Predicted intracellular proteins Evidence at protein level HPA040996, HPA048121 Enhanced Uncertain Vesicles
Cell Junctions Renal cancer:1.83e-6 (favourable), Endometrial cancer:6.37e-4 (favourable), Lung cancer:7.23e-4 (unfavourable) Mixed Tissue enhanced cervix, uterine: 91.4 colon: 79.1 Cell line enhanced CAPAN-2: 33.6;HaCaT: 39.3;SK-BR-3: 55.3 +GNG7 FLJ00058 ENSG00000176533 G protein subunit gamma 7 19 2511219-2702709 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA057790 Supported Renal cancer:0.00e+0 (favourable), Lung cancer:1.35e-5 (favourable), Liver cancer:3.05e-4 (favourable), Pancreatic cancer:3.71e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 49.7 Cell line enhanced REH: 60.2;SK-MEL-30: 23.5;U-266/70: 46.3;U-266/84: 21.0 +OR4C5 OR4C5P, OR4C5Q ENSG00000176540 Olfactory receptor family 4 subfamily C member 5 (gene/pseudogene) 11 48365485-48366465 G-protein coupled receptors, Predicted membrane proteins No evidence HPA049516 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +USF3 KIAA2018 ENSG00000176542 Upstream transcription factor family member 3 3 113648385-113696646 Predicted intracellular proteins Evidence at protein level HPA029243, HPA029245 Uncertain Uncertain Nucleoplasm
Nucleoli
Centrosome Renal cancer:1.74e-6 (favourable) Expressed in all Mixed parathyroid gland: 13.6 Expressed in all +OR4C3 ENSG00000176547 Olfactory receptor family 4 subfamily C member 3 11 48324920-48328471 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA049116 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR4S1 ENSG00000176555 Olfactory receptor family 4 subfamily S member 1 11 48306223-48307152 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +CNTD1 CNTD, FLJ40137 ENSG00000176563 Cyclin N-terminal domain containing 1 17 42798792-42811587 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA023324 Uncertain Nucleoplasm
Plasma membrane
Focal adhesion sites Mixed Tissue enriched 25 testis: 73.1 stomach: 2.9 Cell line enhanced A-431: 2.1;ASC diff: 1.0;SiHa: 1.3 +DCAF4L2 WDR21C ENSG00000176566 DDB1 and CUL4 associated factor 4 like 2 8 87870743-87874068 Predicted intracellular proteins Evidence at protein level HPA067584 Uncertain Tissue enriched Tissue enriched 389 testis: 38.9 all non-specific tissues: 0.0 Cell line enriched 20 U-266/84: 5.1 +OR4X1 ENSG00000176567 Olfactory receptor family 4 subfamily X member 1 (gene/pseudogene) 11 48263861-48264778 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +CNBD1 FLJ35802 ENSG00000176571 Cyclic nucleotide binding domain containing 1 8 86866442-87615219 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA025037, HPA027469, HPA027786 Uncertain Not detected Tissue enriched 13 testis: 11.7 spleen: 0.9 Group enriched 11 Karpas-707: 3.1;U-266/70: 1.9 +KBTBD11 KIAA0711, KLHDC7C ENSG00000176595 Kelch repeat and BTB domain containing 11 8 1973878-2006936 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051159 Uncertain Approved Intermediate filaments Tissue enhanced Tissue enhanced cerebral cortex: 21.7 kidney: 8.8 Cell line enhanced HDLM-2: 12.9;SCLC-21H: 13.6;THP-1: 13.0;U-937: 21.4 +B3GNT5 B3GN-T5, beta3Gn-T5 ENSG00000176597 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 3 183253244-183298504 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017292 Uncertain Approved Nucleoli Renal cancer:1.30e-7 (unfavourable), Pancreatic cancer:7.23e-6 (unfavourable), Liver cancer:5.09e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 49.1 Mixed +MAP3K19 FLJ23074, RCK, YSK4 ENSG00000176601 Mitogen-activated protein kinase kinase kinase 19 2 134964491-135047468 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA011388 Uncertain Cytosol Tissue enhanced Group enriched 8 fallopian tube: 28.5;testis: 7.8 lung: 2.2 Not detected +C14orf177 FLJ25773 ENSG00000176605 Chromosome 14 open reading frame 177 14 98711613-98717761 Predicted intracellular proteins Evidence at transcript level HPA018091 Uncertain Not detected Tissue enriched 23 testis: 2.2 all non-specific tissues: 0.0 Not detected +LMNB2 LMN2 ENSG00000176619 Lamin B2 19 2427638-2456996 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022593, HPA047863, HPA062477 Enhanced Supported Nuclear membrane Renal cancer:9.34e-5 (unfavourable), Prostate cancer:9.53e-5 (unfavourable), Liver cancer:1.32e-4 (unfavourable), Stomach cancer:3.98e-4 (favourable), Melanoma:5.88e-4 (unfavourable) Expressed in all Expressed in all placenta: 21.0 Expressed in all +RMDN1 CGI-90, FAM82B, FLJ20665, RMD1 ENSG00000176623 Regulator of microtubule dynamics 1 8 86468257-86514357 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026495 Approved Supported Actin filaments
Centrosome Renal cancer:8.51e-4 (favourable) Expressed in all Expressed in all thyroid gland: 83.5 Mixed +MEX3C FLJ38871, RKHD2, RNF194 ENSG00000176624 Mex-3 RNA binding family member C 18 51174550-51218304 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040603 Uncertain Approved Vesicles Liver cancer:8.49e-5 (unfavourable) Expressed in all Expressed in all testis: 81.7 Expressed in all +HORMAD2 CT46.2, MGC26710 ENSG00000176635 HORMA domain containing 2 22 30080174-30177075 Predicted intracellular proteins Evidence at protein level HPA003074 Enhanced Not detected Tissue enriched 23 testis: 35.2 liver: 1.5 Not detected +RNF152 FLJ39176 ENSG00000176641 Ring finger protein 152 18 61808063-61894247 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:1.13e-8 (favourable), Stomach cancer:2.85e-5 (unfavourable) Expressed in all Tissue enriched 5 kidney: 56.6 liver: 10.3 Cell line enhanced HaCaT: 18.4;SH-SY5Y: 13.4;U-138 MG: 20.3 +MYO1D KIAA0727, myr4, PPP1R108 ENSG00000176658 Myosin ID 17 32492522-32877177 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054744 Uncertain Approved Cytosol Urothelial cancer:4.53e-6 (unfavourable), Renal cancer:5.01e-6 (favourable) Expressed in all Mixed colon: 109.1 Cell line enhanced CACO-2: 120.9 +FOXL1 FKH6, FKHL11, FREAC7 ENSG00000176678 Forkhead box L1 16 86576368-86582160 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enhanced Tissue enhanced gallbladder: 8.3 duodenum: 3.1 Cell line enhanced CAPAN-2: 33.6;PC-3: 45.9;U-87 MG: 104.7 +TGIF2LY ENSG00000176679 TGFB induced factor homeobox 2 like, Y-linked Y 3579041-3580041 Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Tissue enriched 74 testis: 7.3 all non-specific tissues: 0.0 Not detected +LRRC37A KIAA0563 ENSG00000176681 Leucine rich repeat containing 37A 17 46292733-46337794 Predicted membrane proteins Evidence at protein level HPA042121, HPA042701, HPA043056, HPA045090, HPA049080 Supported Approved Vesicles Not detected Tissue enriched 8 testis: 13.4 skeletal muscle: 1.6 Cell line enhanced Daudi: 2.8 +FOXC2 FKHL14, MFH-1 ENSG00000176692 Forkhead box C2 16 86567251-86569728 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056302 Supported Nucleoplasm
Nuclear bodies Renal cancer:3.57e-7 (unfavourable) Mixed Mixed kidney: 2.8 Cell line enhanced hTEC/SVTERT24-B: 29.9;LHCN-M2: 30.9;TIME: 34.0;U-2197: 34.2;U-87 MG: 27.6 +OR4F17 OR4F11P, OR4F18, OR4F19 ENSG00000176695 Olfactory receptor family 4 subfamily F member 17 19 107461-111696 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +BDNF ENSG00000176697 Brain derived neurotrophic factor 11 27654893-27722058 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009564, HPA031440, HPA056104 Enhanced Supported Nuclear speckles
Mitochondria Mixed Tissue enhanced cerebral cortex: 11.9 epididymis: 4.9 Cell line enhanced BJ: 37.3;BJ hTERT+ SV40 Large T+: 30.7;HBF TERT88: 30.4;U-138 MG: 45.3 +CCDC121 FLJ13646, FLJ43364 ENSG00000176714 Coiled-coil domain containing 121 2 27625639-27629012 Predicted intracellular proteins Evidence at protein level HPA051791 Uncertain Approved Actin filaments
Cytosol Renal cancer:1.87e-5 (favourable), Lung cancer:4.12e-4 (favourable) Expressed in all Tissue enhanced testis: 46.7 ovary: 12.2 Mixed +ACSF3 ENSG00000176715 Acyl-CoA synthetase family member 3 16 89088375-89155846 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:5.97e-6 (favourable), Pancreatic cancer:3.76e-5 (favourable) Expressed in all Expressed in all duodenum: 31.0 Expressed in all +BOK BCL2L9, BOKL, MGC4631 ENSG00000176720 BOK, BCL2 family apoptosis regulator 2 241558721-241574138 Plasma proteins, Predicted membrane proteins Evidence at protein level Renal cancer:1.09e-9 (favourable) Expressed in all Tissue enhanced adipose tissue: 97.4 endometrium,seminal vesicle: 35.9 Mixed +ZNF843 MGC46336 ENSG00000176723 Zinc finger protein 843 16 31432593-31443160 Predicted intracellular proteins Evidence at protein level HPA030911, HPA030912 Uncertain Mixed Mixed ovary: 3.8 Cell line enhanced ASC diff: 1.6;EFO-21: 1.7 +C8orf59 ENSG00000176731 Chromosome 8 open reading frame 59 8 85214076-85220421 Predicted intracellular proteins Evidence at protein level HPA044805, HPA071903 Approved Nucleus
Nucleoli
Cytosol Renal cancer:0.00e+0 (unfavourable) Expressed in all Expressed in all breast: 119.1 Expressed in all +PFN4 ENSG00000176732 Profilin family member 4 2 24115371-24123477 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 39 testis: 139.8 thyroid gland: 3.5 Mixed +OR51V1 OR51A12 ENSG00000176742 Olfactory receptor family 51 subfamily V member 1 11 5199735-5200700 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +MAGEB6 CT3.4, FLJ40242, MAGE-B6, MAGEB6A ENSG00000176746 MAGE family member B6 X 26192440-26195646 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA041853 Approved Tissue enhanced Tissue enriched 58 testis: 5.7 all non-specific tissues: 0.0 Cell line enriched 13 K-562: 4.1 +CDK5R1 Nck5a, p35, p35nck5a ENSG00000176749 Cyclin dependent kinase 5 regulatory subunit 1 17 32486619-32491256 Predicted intracellular proteins Evidence at protein level HPA000252 Supported Nucleoplasm
Vesicles Mixed Tissue enriched 7 cerebral cortex: 98.4 lymph node: 14.7 Cell line enhanced SCLC-21H: 62.8;SK-MEL-30: 30.8 +TCERG1L FLJ38950 ENSG00000176769 Transcription elongation regulator 1 like 10 131092391-131311721 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 6 thyroid gland: 25.1 cerebral cortex: 4.1 Cell line enhanced BEWO: 4.1;U-2 OS: 1.1 +NCKAP5 ERIH1, ERIH2, NAP5 ENSG00000176771 NCK associated protein 5 2 132671799-133568463 Predicted intracellular proteins Evidence at protein level HPA034639, HPA044859 Uncertain Approved Nucleoli
Golgi apparatus
Plasma membrane
Cytosol Mixed Tissue enhanced lung: 17.3 cerebral cortex,kidney: 4.4 Cell line enriched 7 AF22: 45.7 +MAGEB18 MGC33889 ENSG00000176774 MAGE family member B18 X 26138343-26140735 Predicted intracellular proteins Evidence at protein level HPA046141 Enhanced Not detected Tissue enriched 14 testis: 1.3 all non-specific tissues: 0.0 Cell line enriched 29 Karpas-707: 3.1 +DEFB104A DEFB-4, DEFB104, DEFB4 ENSG00000176782 Defensin beta 104A 8 7836471-7841242 Predicted secreted proteins Evidence at protein level HPA045292 Supported Not detected Tissue enriched 609 epididymis: 581.5 esophagus: 0.9 Not detected +RUFY1 FLJ22251, RABIP4, ZFYVE12 ENSG00000176783 RUN and FYVE domain containing 1 5 179550558-179610026 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038804, HPA057614 Approved Supported Nucleus
Vesicles
Cytosol Expressed in all Expressed in all spleen: 20.2 Expressed in all +OR52E2 ENSG00000176787 Olfactory receptor family 52 subfamily E member 2 11 5058650-5059627 G-protein coupled receptors, Predicted membrane proteins No evidence HPA045748 Uncertain Not detected Not detected testis: 0.4 Not detected +BASP1 CAP-23, CAP23, NAP-22, NAP22 ENSG00000176788 Brain abundant membrane attached signal protein 1 5 17065598-17276843 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA045218, HPA050333 Enhanced Enhanced Plasma membrane Renal cancer:5.25e-11 (unfavourable), Head and neck cancer:5.63e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 419.0;epididymis: 369.1 placenta: 130.6 Cell line enhanced HeLa: 555.7;SiHa: 845.8 +DEFB103A DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3 ENSG00000176797 Defensin beta 103A 8 7881204-7882664 Predicted secreted proteins, Transporters Evidence at protein level Not detected Tissue enhanced tonsil: 2.1 skin: 0.8 Not detected +OR51L1 ENSG00000176798 Olfactory receptor family 51 subfamily L member 1 11 4998983-4999930 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +LRRC37A3 FLJ34306, KIAA0563 ENSG00000176809 Leucine rich repeat containing 37 member A3 17 64854312-64919480 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042121, HPA042701, HPA043056, HPA045090 Supported Approved Vesicles Renal cancer:3.25e-6 (unfavourable) Mixed Tissue enhanced testis: 31.6 thyroid gland: 12.5 Mixed +VSIG10 ENSG00000176834 V-set and immunoglobulin domain containing 10 12 118063593-118136026 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA062022 Approved Microtubule organizing center
Cytosol Liver cancer:1.76e-4 (unfavourable), Melanoma:7.53e-4 (unfavourable) Expressed in all Mixed small intestine: 27.7 Cell line enhanced HAP1: 35.3 +IRX5 IRX-2a ENSG00000176842 Iroquois homeobox 5 16 54930862-54934485 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047130 Approved Nuclear speckles
Microtubules
Cytosol Lung cancer:4.59e-4 (favourable) Tissue enhanced Tissue enhanced breast: 17.9;lung: 9.6;skin: 10.1 salivary gland: 4.6 Cell line enhanced RPTEC TERT1: 20.1;T-47d: 34.4 +METRNL ENSG00000176845 Meteorin like, glial cell differentiation regulator 17 83079691-83095119 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023792 Uncertain Expressed in all Mixed skin: 30.9 Cell line enhanced U-138 MG: 117.7;U-2197: 151.1 +FAM91A1 FLJ23790 ENSG00000176853 Family with sequence similarity 91 member A1 8 123768456-123815452 Predicted intracellular proteins Evidence at protein level HPA027978 Approved Approved Nucleoplasm
Microtubules Expressed in all Expressed in all parathyroid gland: 36.7 Expressed in all +WSB2 MGC10210, SBA2 ENSG00000176871 WD repeat and SOCS box containing 2 12 118032694-118062430 Predicted intracellular proteins Evidence at protein level HPA052606 Uncertain Liver cancer:2.42e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 193.2 Expressed in all +GRIN1 GluN1, NMDAR1 ENSG00000176884 Glutamate ionotropic receptor NMDA type subunit 1 9 137138390-137168762 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters Evidence at protein level CAB006831 Approved Mixed Tissue enriched 208 cerebral cortex: 151.8 prostate: 0.7 Cell line enhanced RPMI-8226: 1.8;SCLC-21H: 6.7;SH-SY5Y: 4.2 +SOX11 ENSG00000176887 SRY-box 11 2 5692667-5701385 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000536, CAB056152, CAB056153 Approved Group enriched Tissue enriched 15 cerebral cortex: 5.4 smooth muscle: 0.3 Group enriched 7 AF22: 48.1;NTERA-2: 23.8;REH: 16.5;RH-30: 18.0;SCLC-21H: 35.0;SH-SY5Y: 47.7;WM-115: 11.2 +TYMS HsT422, TMS, TS, Tsase ENSG00000176890 Thymidylate synthetase 18 657604-673578 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002784 Enhanced Liver cancer:5.10e-6 (unfavourable) Expressed in all Mixed testis: 59.1 Expressed in all +OR51G2 ENSG00000176893 Olfactory receptor family 51 subfamily G member 2 11 4914719-4915663 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +PXMP2 PMP22 ENSG00000176894 Peroxisomal membrane protein 2 12 132687606-132704991 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:2.75e-4 (favourable), Head and neck cancer:9.84e-4 (unfavourable) Expressed in all Expressed in all liver: 120.3 Expressed in all +OR51A7 ENSG00000176895 Olfactory receptor family 51 subfamily A member 7 11 4907370-4908308 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA061356 Uncertain Not detected Not detected testis: 0.2 Not detected +TCEANC MGC17403 ENSG00000176896 Transcription elongation factor A N-terminal and central domain containing X 13653189-13681964 Predicted intracellular proteins Evidence at protein level HPA001013 Uncertain Mixed Mixed epididymis: 3.6 Mixed +OR51T1 ENSG00000176900 Olfactory receptor family 51 subfamily T member 1 11 4881819-4882883 G-protein coupled receptors, Predicted membrane proteins No evidence HPA046877 Uncertain Not detected Not detected prostate: 0.1 Not detected +PNMA1 MA1 ENSG00000176903 Paraneoplastic Ma antigen 1 14 73711783-73714372 Predicted intracellular proteins Evidence at protein level HPA003817, HPA015007 Enhanced Supported Focal adhesion sites
Cytosol Liver cancer:3.00e-5 (unfavourable), Urothelial cancer:4.51e-5 (unfavourable), Head and neck cancer:7.49e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 193.5 Mixed +OR51H1 OR51H1P ENSG00000176904 Olfactory receptor family 51 subfamily H member 1 11 4859656-4860564 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.5 Not detected +C8orf4 hTC-1, TC-1, TC1 ENSG00000176907 Chromosome 8 open reading frame 4 8 40153455-40155308 Predicted intracellular proteins Evidence at protein level HPA027188 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Mixed placenta: 233.9 Cell line enhanced AF22: 130.7;BJ hTERT+: 107.2;EFO-21: 81.1;HeLa: 56.7;RPTEC TERT1: 49.9 +MAMSTR FLJ36070, MASTR ENSG00000176909 MEF2 activating motif and SAP domain containing transcriptional regulator 19 48712742-48719721 Predicted intracellular proteins Evidence at transcript level HPA049765 Approved Nuclear speckles Expressed in all Tissue enhanced adrenal gland: 21.4;skeletal muscle: 31.4 fallopian tube: 10.4 Cell line enhanced RH-30: 16.1 +ANKLE2 KIAA0692, Lem4, LEMD7 ENSG00000176915 Ankyrin repeat and LEM domain containing 2 12 132725503-132761888 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003602, HPA074838 Uncertain Supported Endoplasmic reticulum
Plasma membrane Renal cancer:1.90e-8 (unfavourable), Liver cancer:3.97e-6 (unfavourable) Expressed in all Expressed in all testis: 80.4 Expressed in all +C8G ENSG00000176919 Complement C8 gamma chain 9 136945246-136946974 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA046269 Approved Uncertain Endoplasmic reticulum Colorectal cancer:2.99e-4 (unfavourable) Tissue enriched Group enriched 6 duodenum: 49.8;liver: 106.5;small intestine: 34.5 gallbladder: 9.8 Cell line enriched 16 HMC-1: 139.2 +FUT2 SE, Se2, SEC2, sej ENSG00000176920 Fucosyltransferase 2 19 48695971-48705950 Blood group antigen proteins, Enzymes, Predicted membrane proteins Evidence at protein level HPA014402 Uncertain Uncertain Plasma membrane
Cytosol Head and neck cancer:5.83e-4 (favourable) Mixed Tissue enhanced duodenum: 51.4 stomach: 32.2 Cell line enriched 6 CAPAN-2: 68.6 +OR51S1 ENSG00000176922 Olfactory receptor family 51 subfamily S member 1 11 4848237-4849208 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.1 Not detected +OR51F2 ENSG00000176925 Olfactory receptor family 51 subfamily F member 2 11 4821386-4822414 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +EFCAB5 FLJ46247 ENSG00000176927 EF-hand calcium binding domain 5 17 29929200-30108452 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 12 testis: 15.2 rectum: 1.2 Cell line enhanced RPTEC TERT1: 2.2 +GCNT4 C2GNT3 ENSG00000176928 Glucosaminyl (N-acetyl) transferase 4, core 2 5 75025346-75030899 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037431 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:1.93e-7 (favourable) Mixed Mixed duodenum: 21.4 Cell line enriched 5 RT4: 25.9 +MUC20 FLJ14408, KIAA1359 ENSG00000176945 Mucin 20, cell surface associated 3 195720882-195741123 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042249 Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.57e-4 (favourable) Mixed Mixed colon: 10.4 Cell line enriched 7 SK-BR-3: 20.9 +THAP4 CGI-36 ENSG00000176946 THAP domain containing 4 2 241584405-241637449 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA044982, HPA053448 Uncertain Approved Nucleoplasm
Nuclear speckles Renal cancer:1.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 83.1 Expressed in all +NFATC2IP ESC2, FLJ14639, NIP45, RAD60 ENSG00000176953 Nuclear factor of activated T-cells 2 interacting protein 16 28950807-28967097 Predicted intracellular proteins Evidence at protein level HPA053587 Approved Nucleus Renal cancer:1.03e-5 (unfavourable), Prostate cancer:5.23e-4 (unfavourable) Expressed in all Expressed in all testis: 43.1 Expressed in all +LY6H NMLY6 ENSG00000176956 Lymphocyte antigen 6 family member H 8 143157914-143160711 Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 15 cerebral cortex: 38.0 duodenum: 2.5 Cell line enhanced MOLT-4: 2.0;SCLC-21H: 1.5 +FIBIN MGC24932 ENSG00000176971 Fin bud initiation factor homolog (zebrafish) 11 26994184-26996121 Predicted secreted proteins Evidence at protein level HPA040120 Uncertain Thyroid cancer:1.85e-6 (unfavourable), Renal cancer:1.93e-5 (favourable), Stomach cancer:6.72e-4 (unfavourable) Expressed in all Tissue enhanced seminal vesicle: 124.4 lung: 37.5 Group enriched 9 ASC diff: 67.5;ASC TERT1: 43.5;fHDF/TERT166: 24.9;HHSteC: 106.9;HSkMC: 96.0;hTCEpi: 25.5 +FAM89B LRAP25, MTVR1 ENSG00000176973 Family with sequence similarity 89 member B 11 65572349-65574198 Predicted intracellular proteins Evidence at protein level HPA046895 Approved Renal cancer:9.48e-5 (unfavourable), Liver cancer:2.98e-4 (unfavourable), Ovarian cancer:6.00e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 38.5 Expressed in all +SHMT1 CSHMT, MGC15229, MGC24556, SHMT ENSG00000176974 Serine hydroxymethyltransferase 1 17 18327860-18363563 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023314 Approved Supported Nucleus
Cytosol Renal cancer:8.54e-6 (favourable), Liver cancer:2.52e-4 (favourable) Expressed in all Expressed in all kidney: 271.5 Expressed in all +DPP7 DPP2, DPPII ENSG00000176978 Dipeptidyl peptidase 7 9 137110542-137115177 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021282, CAB025541, HPA059381 Supported Enhanced Golgi apparatus
Vesicles Colorectal cancer:6.07e-6 (unfavourable), Pancreatic cancer:8.31e-5 (favourable) Expressed in all Expressed in all adrenal gland: 70.7 Mixed +TRIM60 FLJ35882, RNF129, RNF33 ENSG00000176979 Tripartite motif containing 60 4 165031953-165041744 Predicted intracellular proteins Evidence at transcript level HPA035809, HPA035810, HPA061496 Uncertain Tissue enriched Group enriched 13 placenta: 2.1;testis: 2.7 skin: 0.1 Cell line enriched 17 BEWO: 13.5 +SEC24C KIAA0079 ENSG00000176986 SEC24 homolog C, COPII coat complex component 10 73744384-73772161 Predicted intracellular proteins Evidence at protein level HPA040196, HPA040213 Supported Supported Vesicles Expressed in all Expressed in all parathyroid gland: 85.5 Expressed in all +FMR1NB CT37, FLJ25736, NY-SAR-35 ENSG00000176988 Fragile X mental retardation 1 neighbor X 147981329-148026667 Predicted membrane proteins Evidence at protein level HPA011284, CAB026403 Enhanced Tissue enhanced Tissue enriched 415 testis: 86.9 epididymis: 0.2 Group enriched 24 U-266/70: 50.9;U-266/84: 39.2 +SMCR8 FLJ34716 ENSG00000176994 Smith-Magenis syndrome chromosome region, candidate 8 17 18315310-18328055 Predicted intracellular proteins Evidence at protein level HPA021557, HPA024646 Uncertain Enhanced Nucleoplasm Renal cancer:1.35e-4 (favourable) Expressed in all Mixed parathyroid gland: 9.0 Expressed in all +MTHFR ENSG00000177000 Methylenetetrahydrofolate reductase 1 11785723-11806920 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA063389 Approved Cell Junctions Head and neck cancer:3.97e-5 (favourable), Pancreatic cancer:4.81e-5 (favourable), Liver cancer:1.19e-4 (unfavourable), Renal cancer:2.12e-4 (favourable) Expressed in all Expressed in all epididymis: 64.9 Expressed in all +DEFB104B ENSG00000177023 Defensin beta 104B 8 7470308-7475082 Predicted secreted proteins Evidence at protein level HPA045292 Supported Not detected Tissue enriched 609 epididymis: 581.5 esophagus: 0.9 Not detected +C19orf18 MGC41906 ENSG00000177025 Chromosome 19 open reading frame 18 19 57958437-57974534 Predicted membrane proteins Evidence at transcript level HPA014527 Uncertain Approved Golgi apparatus Endometrial cancer:5.07e-4 (favourable) Mixed Tissue enhanced testis: 17.0 epididymis: 4.9 Cell line enhanced HEK 293: 2.7 +DEAF1 NUDR, SPN, ZMYND5 ENSG00000177030 DEAF1, transcription factor 11 644233-706715 Disease related genes, Predicted secreted proteins, Transcription factors Evidence at protein level HPA030302 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:1.75e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 40.6 Expressed in all +MTX3 ENSG00000177034 Metaxin 3 5 79976731-79991262 Predicted intracellular proteins Evidence at protein level HPA047858, HPA062061 Approved Approved Mitochondria Liver cancer:5.08e-5 (unfavourable), Ovarian cancer:2.54e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.6 Mixed +TMEM80 FLJ38216 ENSG00000177042 Transmembrane protein 80 11 695428-705028 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA059592, HPA067046 Uncertain Approved Golgi apparatus Renal cancer:2.47e-4 (favourable) Expressed in all Expressed in all thyroid gland: 43.5 Expressed in all +SIX5 DMAHP ENSG00000177045 SIX homeobox 5 19 45764785-45769226 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042068 Approved Expressed in all Mixed ovary: 33.7 Mixed +IFNW1 ENSG00000177047 Interferon omega 1 9 21140214-21142145 Predicted secreted proteins Evidence at protein level Not detected Not detected bone marrow,lymph node,skin,testis,thyroid gland: 0.1 Not detected +FBXO46 20D7-FC4, Fbx46, FBXO34L ENSG00000177051 F-box protein 46 19 45710629-45730904 Predicted intracellular proteins Evidence at protein level HPA049390 Uncertain Approved Nucleus
Vesicles
Cytosol Urothelial cancer:5.09e-6 (favourable), Endometrial cancer:2.13e-5 (unfavourable), Liver cancer:1.11e-4 (unfavourable), Renal cancer:5.33e-4 (unfavourable), Head and neck cancer:5.44e-4 (favourable), Pancreatic cancer:8.11e-4 (favourable) Expressed in all Expressed in all endometrium: 17.7 Expressed in all +ZDHHC13 FLJ10852, FLJ10941, HIP14L ENSG00000177054 Zinc finger DHHC-type containing 13 11 19117099-19176422 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level HPA016759, HPA018791 Uncertain Enhanced Vesicles Expressed in all Mixed esophagus: 40.4 Expressed in all +SLC38A9 FLJ90709 ENSG00000177058 Solute carrier family 38 member 9 5 55625845-55773194 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA043785 Uncertain Approved Nucleoplasm
Vesicles Endometrial cancer:7.24e-5 (unfavourable) Expressed in all Expressed in all placenta: 80.4 Expressed in all +ACER2 ALKCDase2, ASAH3L, FLJ41587 ENSG00000177076 Alkaline ceramidase 2 9 19409059-19452020 Enzymes, Predicted membrane proteins Evidence at protein level Tissue enhanced Group enriched 5 placenta: 14.8;stomach: 62.9;urinary bladder: 44.1 skin: 7.6 Group enriched 5 BEWO: 30.0;RT4: 62.6 +WDR73 FLJ14888, HSPC264 ENSG00000177082 WD repeat domain 73 15 84639281-84654343 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039357 Uncertain Mixed Mixed endometrium: 5.7 Expressed in all +POLE POLE1 ENSG00000177084 DNA polymerase epsilon, catalytic subunit 12 132623753-132687365 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058210, HPA067385 Enhanced Nucleus
Plasma membrane Renal cancer:3.19e-8 (unfavourable), Melanoma:1.44e-4 (unfavourable) Expressed in all Expressed in all testis: 22.1 Expressed in all +FAM109B DKFZp686J07229, IPIP27B, SES2 ENSG00000177096 Family with sequence similarity 109 member B 22 42074251-42079441 Predicted intracellular proteins Evidence at protein level HPA000647 Uncertain Expressed in all Mixed placenta: 22.5 Mixed +SCN4B LQT10 ENSG00000177098 Sodium voltage-gated channel beta subunit 4 11 118133377-118152888 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA017293 Approved Mixed Tissue enhanced adipose tissue: 25.0 thyroid gland: 17.0 Cell line enhanced AN3-CA: 1.2;NTERA-2: 1.4;U-2 OS: 1.4 +DSCAML1 KIAA1132 ENSG00000177103 DS cell adhesion molecule like 1 11 117427773-117817525 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035230 Uncertain Renal cancer:8.37e-4 (favourable) Group enriched Tissue enhanced cerebral cortex: 12.1 ovary: 4.4 Cell line enhanced EFO-21: 6.2;RPTEC TERT1: 3.7;T-47d: 8.5 +RHOG ARHG, MGC125835, MGC125836, RhoG ENSG00000177105 Ras homolog family member G 11 3826978-3840983 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039871 Enhanced Renal cancer:9.49e-8 (unfavourable), Colorectal cancer:1.81e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 170.5 Expressed in all +EPS8L2 FLJ21935, FLJ22171, MGC3088 ENSG00000177106 EPS8 like 2 11 694438-727727 Predicted intracellular proteins Evidence at protein level HPA041143 Approved Supported Plasma membrane
Cytosol Glioma:1.80e-4 (unfavourable) Expressed in all Mixed small intestine: 110.4 Cell line enhanced A-431: 186.2;BEWO: 194.1;CAPAN-2: 171.1;SK-BR-3: 177.2 +ZDHHC22 C14orf59 ENSG00000177108 Zinc finger DHHC-type containing 22 14 77131270-77142734 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049471, HPA072213 Enhanced Plasma membrane Tissue enriched Tissue enriched 113 cerebral cortex: 64.2 testis: 0.5 Cell line enhanced AF22: 3.6;NTERA-2: 3.8;RH-30: 6.2;SCLC-21H: 8.2 +ANO6 DKFZp313M0720, TMEM16F ENSG00000177119 Anoctamin 6 12 45215987-45440404 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA038958 Approved Approved Plasma membrane
Cytosol Breast cancer:7.56e-5 (unfavourable), Cervical cancer:3.82e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 91.1 Expressed in all +ZBTB34 KIAA1993, MGC24652, ZNF918 ENSG00000177125 Zinc finger and BTB domain containing 34 9 126860665-126885878 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023893 Approved Supported Nucleoplasm Expressed in all Mixed placenta: 9.6 Expressed in all +FAM9B TEX39B ENSG00000177138 Family with sequence similarity 9 member B X 9024232-9164639 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035135 Uncertain Uncertain Nucleoplasm Not detected Tissue enriched 32 testis: 10.3 prostate,skin: 0.3 Group enriched 38 U-266/70: 21.4;U-266/84: 22.5 +CETN1 CEN1, CETN ENSG00000177143 Centrin 1 18 580357-582114 Predicted intracellular proteins Evidence at protein level HPA028956, CAB037244 Approved Tissue enriched Tissue enriched 1424 testis: 142.4 all non-specific tissues: 0.0 Not detected +NUDT4P1 ENSG00000177144 Nudix hydrolase 4 pseudogene 1 1 148748894-148750099 Predicted intracellular proteins Evidence at protein level HPA017593, HPA047027, HPA057684 Approved Approved Cytosol Not detected Mixed gallbladder: 25.4 Cell line enhanced CACO-2: 28.7;RT4: 24.9 +FAM210A C18orf19, HsT2329, MGC24180 ENSG00000177150 Family with sequence similarity 210 member A 18 13663347-13726663 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014324, HPA051564 Uncertain Approved Nucleus
Golgi apparatus
Mitochondria Head and neck cancer:8.14e-4 (unfavourable) Expressed in all Mixed testis: 15.7 Expressed in all +OR2T35 ENSG00000177151 Olfactory receptor family 2 subfamily T member 35 1 248638287-248639258 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +TALDO1 ENSG00000177156 Transaldolase 1 11 747329-765024 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA040373, HPA048089 Enhanced Nucleoplasm
Cytosol Liver cancer:2.29e-4 (unfavourable) Expressed in all Expressed in all esophagus: 262.9 Expressed in all +ULK1 ATG1, ATG1A ENSG00000177169 Unc-51 like autophagy activating kinase 1 12 131894651-131923167 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063990 Approved Cytosol Expressed in all Expressed in all skin: 23.7 Expressed in all +OR14C36 OR5BF1 ENSG00000177174 Olfactory receptor family 14 subfamily C member 36 1 248348775-248349713 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected prostate: 0.1 Not detected +RIMKLA FAM80A, MGC47816, NAAGS-II, RP11-157D18.1 ENSG00000177181 Ribosomal modification protein rimK like family member A 1 42380795-42422578 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027826 Uncertain Uncertain Nucleoli fibrillar center Lung cancer:1.43e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 10.2 parathyroid gland,rectum: 3.8 Cell line enhanced AN3-CA: 6.7;SCLC-21H: 12.8 +CLVS1 C6orf212L, CRALBPL, MGC34646, RLBP1L1 ENSG00000177182 Clavesin 1 8 61057158-61501645 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 10.3 testis: 3.7 Cell line enhanced SCLC-21H: 4.4;SH-SY5Y: 1.7 +OR2M7 ENSG00000177186 Olfactory receptor family 2 subfamily M member 7 1 248323630-248324568 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +RPS6KA3 CLS, HU-3, MRX19, RSK, RSK2 ENSG00000177189 Ribosomal protein S6 kinase A3 X 20149911-20267100 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003221, CAB003853, CAB013520 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all parathyroid gland: 92.7 Mixed +B3GNT8 B3GALT7, beta3Gn-T8, BGALT15 ENSG00000177191 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 19 41425359-41428730 Predicted secreted proteins Evidence at protein level HPA043669 Enhanced Pancreatic cancer:9.31e-6 (favourable), Endometrial cancer:4.11e-4 (unfavourable) Mixed Tissue enhanced duodenum: 15.5;small intestine: 16.8 esophagus: 10.7 Cell line enhanced HMC-1: 5.7;HUVEC TERT2: 2.9;U-937: 4.3 +PUS1 ENSG00000177192 Pseudouridylate synthase 1 12 131929200-131945896 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA051636, HPA057593 Approved Supported Nucleus
Mitochondria Renal cancer:3.49e-8 (unfavourable) Expressed in all Expressed in all lymph node: 21.4 Expressed in all +CHD9 BC022889, FLJ12178, KIAA0308 ENSG00000177200 Chromodomain helicase DNA binding protein 9 16 53055033-53329150 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042053, HPA049420 Approved Approved Plasma membrane
Cytosol Renal cancer:1.84e-4 (favourable) Expressed in all Mixed parathyroid gland: 28.2 Expressed in all +OR2T12 ENSG00000177201 Olfactory receptor family 2 subfamily T member 12 1 248294616-248295578 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +SPACA4 SAMP14 ENSG00000177202 Sperm acrosome associated 4 19 48606743-48607714 Predicted secreted proteins Evidence at protein level HPA041927, HPA061302 Enhanced Mixed Tissue enriched 18 testis: 64.9 stomach: 3.5 Not detected +OR2T33 ENSG00000177212 Olfactory receptor family 2 subfamily T member 33 1 248272852-248273814 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected bone marrow,testis: 0.2 Not detected +PDDC1 FLJ34283 ENSG00000177225 Parkinson disease 7 domain containing 1 11 767220-777488 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008812 Uncertain Supported Nucleoplasm Renal cancer:3.79e-5 (favourable), Liver cancer:3.98e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 31.7 Expressed in all +TRIM72 MG53 ENSG00000177238 Tripartite motif containing 72 16 31214021-31231537 Predicted intracellular proteins, Transporters Evidence at protein level HPA023122, HPA054909 Enhanced Approved Nucleus
Nucleoli Mixed Tissue enriched 19 skeletal muscle: 52.4 prostate: 2.8 Cell line enhanced LHCN-M2: 9.1;RH-30: 27.1;U-266/70: 13.3 +MAN1B1 ERManI, MANA-ER, MRT15 ENSG00000177239 Mannosidase alpha class 1B member 1 9 137086927-137109187 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051516 Approved Uncertain Vesicles Liver cancer:1.45e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 33.4 Expressed in all +DEFB103B ENSG00000177243 Defensin beta 103B 8 7428888-7430348 Predicted secreted proteins, Transporters Evidence at protein level Not detected Tissue enhanced tonsil: 2.1 skin: 0.8 Not detected +DEFB4B DEFB4P ENSG00000177257 Defensin beta 4B 8 7414860-7416863 Predicted secreted proteins, Transporters Evidence at protein level Tissue enhanced Tissue enriched 19 tonsil: 2.7 lung,skin: 0.1 Not detected +KCNA3 HLK3, HPCN3, Kv1.3, MK3 ENSG00000177272 Potassium voltage-gated channel subfamily A member 3 1 110672465-110675033 FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA016625 Approved Mixed Mixed lymph node: 10.5 Cell line enhanced HDLM-2: 20.5;Karpas-707: 31.5;U-266/70: 23.9;U-266/84: 21.1 +OR2AJ1 OR2AJ1P, OR2AJ1Q ENSG00000177275 Olfactory receptor family 2 subfamily AJ member 1 1 247933769-247934755 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected spleen: 0.1 Not detected +FZD8 ENSG00000177283 Frizzled class receptor 8 10 35638249-35642278 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA045025, HPA071142 Approved Approved Endoplasmic reticulum Pancreatic cancer:8.21e-4 (favourable) Expressed in all Tissue enhanced spleen: 15.9 lung: 6.6 Cell line enhanced PC-3: 37.6;U-138 MG: 14.7 +GJD4 CX40.1, FLJ90023 ENSG00000177291 Gap junction protein delta 4 10 35605410-35608935 Predicted membrane proteins, Transporters Evidence at transcript level HPA038266 Uncertain Not detected Tissue enhanced cerebral cortex: 1.7 skin: 1.0 Cell line enhanced RH-30: 1.6 +FBXO39 CT144, Fbx39, MGC35179 ENSG00000177294 F-box protein 39 17 6776223-6797101 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 62 testis: 53.5 ovary: 0.8 Not detected +CLDN22 CLDN21 ENSG00000177300 Claudin 22 4 183318194-183320774 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Tissue enhanced fallopian tube: 1.0 endometrium: 0.2 Not detected +KCNA2 HK4, Kv1.2 ENSG00000177301 Potassium voltage-gated channel subfamily A member 2 1 110519837-110631474 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB001976 Enhanced Tissue enhanced Tissue enriched 6 cerebral cortex: 23.2 thyroid gland: 4.1 Cell line enhanced Karpas-707: 4.4;SCLC-21H: 1.8;U-2 OS: 1.4;U-266/70: 1.5;U-266/84: 2.3;WM-115: 1.6 +TOP3A TOP3, ZGRF7 ENSG00000177302 Topoisomerase (DNA) III alpha 17 18271428-18315007 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB002449 Approved Pancreatic cancer:1.39e-4 (favourable), Prostate cancer:4.59e-4 (unfavourable) Expressed in all Mixed testis: 12.4 Expressed in all +CASKIN2 ANKS5B, FLJ21609, KIAA1139 ENSG00000177303 CASK interacting protein 2 17 75500261-75515583 Predicted intracellular proteins Evidence at protein level HPA071906, HPA075184 Enhanced Enhanced Plasma membrane Renal cancer:4.83e-8 (favourable), Pancreatic cancer:2.47e-5 (favourable) Expressed in all Mixed lung: 29.0 Mixed +ZBTB38 CIBZ, FLJ35036, PPP1R171, ZNF921 ENSG00000177311 Zinc finger and BTB domain containing 38 3 141324213-141449792 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA014865, HPA059378 Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 126.8 Cell line enhanced RPMI-8226: 273.3 +BEND2 CXorf20, MGC33653 ENSG00000177324 BEN domain containing 2 X 18162931-18220883 Predicted intracellular proteins Evidence at protein level HPA009420, HPA013142 Enhanced Not detected Tissue enriched 30 testis: 9.9 spleen: 0.3 Not detected +CCDC71 FLJ12800 ENSG00000177352 Coiled-coil domain containing 71 3 49162535-49166321 Predicted intracellular proteins Evidence at protein level HPA047547 Uncertain Approved Nuclear membrane Renal cancer:9.65e-9 (favourable) Expressed in all Expressed in all thyroid gland: 27.2 Expressed in all +C10orf71 FLJ45913 ENSG00000177354 Chromosome 10 open reading frame 71 10 49299193-49327487 Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 34 heart muscle: 28.8;parathyroid gland: 74.8;skeletal muscle: 97.7 prostate: 1.9 Group enriched 17 K-562: 6.2;RH-30: 9.6 +OVOS2 ENSG00000177359 12 31111652-31206154 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enriched 8 testis: 2.8 stomach: 0.3 Cell line enhanced U-266/70: 1.0 +LRRN4CL ENSG00000177363 LRRN4 C-terminal like 11 62686402-62689899 Predicted membrane proteins Evidence at protein level HPA050317 Enhanced Approved Nucleoplasm
Nuclear bodies Tissue enriched Mixed endometrium: 16.8 Cell line enhanced ASC TERT1: 15.0;HHSteC: 14.1;HSkMC: 6.6;LHCN-M2: 9.5 +TIMM22 TEX4, TIM22 ENSG00000177370 Translocase of inner mitochondrial membrane 22 17 997117-1003671 Predicted membrane proteins Evidence at protein level HPA045138 Uncertain Renal cancer:1.41e-4 (favourable), Pancreatic cancer:3.42e-4 (favourable) Expressed in all Mixed parathyroid gland: 4.4 Expressed in all +HIC1 ZBTB29, ZNF901 ENSG00000177374 HIC ZBTB transcriptional repressor 1 17 2054154-2063241 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043372 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:9.36e-6 (unfavourable) Expressed in all Mixed endometrium: 16.3 Cell line enhanced BJ: 10.1;TIME: 10.1 +PPFIA3 KIAA0654, LPNA3, MGC126567, MGC126569 ENSG00000177380 PTPRF interacting protein alpha 3 19 49119389-49151026 Predicted intracellular proteins Evidence at protein level HPA043567, HPA050340 Enhanced Uncertain Nucleoli fibrillar center
Vesicles Head and neck cancer:6.46e-7 (favourable), Liver cancer:2.24e-5 (unfavourable), Breast cancer:3.09e-4 (unfavourable), Endometrial cancer:8.65e-4 (favourable) Expressed in all Group enriched 6 cerebral cortex: 21.5;skin: 20.2 parathyroid gland: 3.6 Cell line enhanced PC-3: 33.5 +MAGEF1 ENSG00000177383 MAGE family member F1 3 184710367-184712002 Predicted intracellular proteins Evidence at protein level HPA046899, HPA054190 Uncertain Approved Actin filaments Renal cancer:7.59e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 60.1 Expressed in all +UMODL1 ENSG00000177398 Uromodulin like 1 21 42062959-42143453 Predicted membrane proteins Evidence at protein level HPA067245 Uncertain Group enriched Group enriched 7 fallopian tube: 1.7;testis: 1.7 small intestine: 0.2 Group enriched 6 SCLC-21H: 1.8;U-266/70: 2.9 +SAMD9L C7orf6, FLJ39885, KIAA2005 ENSG00000177409 Sterile alpha motif domain containing 9 like 7 93130055-93148369 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019461, HPA019465, HPA019488 Enhanced Approved Cytosol Renal cancer:6.63e-5 (unfavourable) Expressed in all Mixed spleen: 52.5 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 52.6;HDLM-2: 47.0;Karpas-707: 94.3 +UBE2U MGC35130 ENSG00000177414 Ubiquitin conjugating enzyme E2 U (putative) 1 64203627-64267368 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 39 testis: 79.4 stomach: 2.0 Not detected +PAWR par-4, PAR4 ENSG00000177425 Pro-apoptotic WT1 regulator 12 79574979-79691097 Predicted intracellular proteins Evidence at protein level HPA012640, CAB020779 Approved Enhanced Plasma membrane
Actin filaments Expressed in all Mixed endometrium: 45.4 Mixed +TGIF1 HPE4, TGIF ENSG00000177426 TGFB induced factor homeobox 1 18 3411608-3459978 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062160 Supported Nucleoplasm Pancreatic cancer:6.47e-4 (unfavourable) Expressed in all Expressed in all epididymis: 162.4 Mixed +MIEF2 MGC23130, MiD49, SMCR7 ENSG00000177427 Mitochondrial elongation factor 2 17 18260534-18266552 Predicted membrane proteins Evidence at protein level HPA042334 Uncertain Renal cancer:1.75e-7 (favourable) Expressed in all Mixed skeletal muscle: 7.0 Mixed +NAP1L5 DRLM ENSG00000177432 Nucleosome assembly protein 1 like 5 4 88695915-88698235 Predicted intracellular proteins Evidence at protein level HPA058227 Approved Approved Nucleoplasm
Cytosol Expressed in all Tissue enhanced cerebral cortex: 91.1 adrenal gland: 29.5 Cell line enhanced SH-SY5Y: 42.7 +NIM1K MGC42105, NIM1 ENSG00000177453 NIM1 serine/threonine protein kinase 5 43192071-43280850 Enzymes, Predicted membrane proteins Evidence at protein level HPA007695 Uncertain Approved Cytosol Tissue enriched Tissue enriched 8 cerebral cortex: 16.3 lung: 2.0 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 1.9;HDLM-2: 2.1;PC-3: 2.4;U-87 MG: 2.6 +CD19 ENSG00000177455 CD19 molecule 16 28931939-28939346 CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB016110 Enhanced Mixed Group enriched 11 appendix: 37.4;lymph node: 84.0;spleen: 47.4;tonsil: 68.3 urinary bladder: 5.5 Group enriched 40 Daudi: 103.6;REH: 70.5;U-698: 22.6 +ERICH5 C8orf47, FLJ39553 ENSG00000177459 Glutamate rich 5 8 98064311-98093610 Predicted intracellular proteins Evidence at protein level HPA025070, HPA025293, HPA027233 Enhanced Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:3.76e-4 (favourable), Urothelial cancer:9.38e-4 (favourable) Tissue enhanced Tissue enhanced fallopian tube: 13.8;gallbladder: 13.7 stomach: 9.2 Cell line enhanced A549: 6.1;HAP1: 6.4;HEK 293: 8.2;RT4: 12.7 +OR2T8 OR2T8P ENSG00000177462 Olfactory receptor family 2 subfamily T member 8 1 247921018-247921956 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced thyroid gland: 1.2 testis: 0.4 Not detected +NR2C2 hTAK1, TAK1, TR2R1, TR4 ENSG00000177463 Nuclear receptor subfamily 2 group C member 2 3 14947584-15053600 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006313 Approved Enhanced Nucleoplasm Head and neck cancer:1.51e-5 (favourable) Expressed in all Expressed in all testis: 38.6 Expressed in all +GPR4 ENSG00000177464 G protein-coupled receptor 4 19 45589764-45602208 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA014278 Uncertain Renal cancer:2.07e-5 (unfavourable), Lung cancer:9.19e-4 (unfavourable) Expressed in all Mixed adipose tissue: 10.3 Group enriched 11 HUVEC TERT2: 15.6;TIME: 25.6 +ACOT4 FLJ31235, PTE-Ib, PTE2B ENSG00000177465 Acyl-CoA thioesterase 4 14 73591706-73596496 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000779 Enhanced Renal cancer:8.43e-5 (favourable), Pancreatic cancer:1.77e-4 (unfavourable) Expressed in all Tissue enhanced kidney: 8.9 liver: 4.9 Cell line enhanced CAPAN-2: 9.1;SK-BR-3: 12.3;T-47d: 38.6 +OLIG3 Bhlhb7, bHLHe20 ENSG00000177468 Oligodendrocyte transcription factor 3 6 137492202-137494250 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018303, CAB024865 Uncertain Not detected Not detected esophagus: 0.1 Cell line enhanced NTERA-2: 1.2 +PTRF cavin-1, CAVIN1 ENSG00000177469 Polymerase I and transcript release factor 17 42402452-42423517 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049838, HPA074213 Supported Supported Vesicles
Plasma membrane Urothelial cancer:5.87e-4 (unfavourable), Ovarian cancer:5.92e-4 (unfavourable), Colorectal cancer:6.36e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 343.1 Cell line enhanced BJ: 868.3;U-138 MG: 835.1 +OR2G3 ENSG00000177476 Olfactory receptor family 2 subfamily G member 3 1 247605586-247606515 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ARIH2 TRIAD1 ENSG00000177479 Ariadne RBR E3 ubiquitin protein ligase 2 3 48918821-48986382 Predicted intracellular proteins Evidence at protein level HPA067381, HPA069715, HPA070963 Enhanced Nucleoplasm Liver cancer:1.70e-4 (unfavourable), Renal cancer:6.60e-4 (favourable), Pancreatic cancer:7.31e-4 (favourable) Expressed in all Expressed in all testis: 49.6 Expressed in all +RBM44 FLJ40411 ENSG00000177483 RNA binding motif protein 44 2 237798389-237842808 Predicted intracellular proteins Evidence at protein level HPA003298 Enhanced Not detected Tissue enriched 61 testis: 35.7 bone marrow,lung: 0.5 Not detected +ZBTB33 kaiso, WUGSC:H_DJ525N14.1, ZNF-kaiso, ZNF348 ENSG00000177485 Zinc finger and BTB domain containing 33 X 120250752-120258398 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000755, CAB001980, HPA005732 Approved Enhanced Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 23.4 Expressed in all +OR2G2 ENSG00000177489 Olfactory receptor family 2 subfamily G member 2 1 247588360-247589313 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ZBED2 MGC10796 ENSG00000177494 Zinc finger BED-type containing 2 3 111592900-111595443 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029786 Approved Nuclear bodies
Mitochondria
Cytosol Pancreatic cancer:8.83e-4 (unfavourable) Tissue enriched Tissue enhanced fallopian tube: 30.3;thyroid gland: 113.1 lung: 14.9 Cell line enhanced CAPAN-2: 45.9;EFO-21: 33.6;HaCaT: 44.7;HBEC3-KT: 81.4;RPTEC TERT1: 56.1 +VCX2 VCX-2r ENSG00000177504 Variable charge, X-linked 2 X 8169944-8171267 Predicted intracellular proteins Evidence at protein level HPA044642, HPA044996, HPA049357 Enhanced Tissue enhanced Tissue enriched 32 testis: 3.1 all non-specific tissues: 0.0 Not detected +IRX3 IRX-1 ENSG00000177508 Iroquois homeobox 3 16 54283304-54286763 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062522 Approved Vesicles Expressed in all Tissue enhanced breast: 96.6 skin: 70.5 Cell line enhanced NB-4: 129.5;RPTEC TERT1: 178.7;T-47d: 115.6;THP-1: 136.2 +ST8SIA3 SIAT8C ENSG00000177511 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 18 57350813-57371731 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA063398, HPA066783 Supported Supported Golgi apparatus Group enriched Tissue enriched 7 cerebral cortex: 31.8 adrenal gland: 4.8 Group enriched 67 NTERA-2: 4.3;SCLC-21H: 8.6;SH-SY5Y: 8.7 +RPRM FLJ90327, REPRIMO ENSG00000177519 Reprimo, TP53 dependent G2 arrest mediator candidate 2 153477338-153478808 Predicted membrane proteins Evidence at protein level Group enriched Tissue enhanced cerebral cortex: 21.2;endometrium: 21.8 smooth muscle: 17.4 Group enriched 6 HEK 293: 22.9;MCF7: 21.9;NTERA-2: 19.8;SCLC-21H: 8.5;SH-SY5Y: 8.7 +OR2B11 ENSG00000177535 Olfactory receptor family 2 subfamily B member 11 1 247451029-247451982 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047459 Uncertain Not detected Not detected bone marrow: 0.4 Not detected +SLC25A22 EIEE3, FLJ13044, GC1, NET44 ENSG00000177542 Solute carrier family 25 member 22 11 790475-798333 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA014662 Approved Enhanced Nucleoplasm
Mitochondria Expressed in all Tissue enriched 6 cerebral cortex: 89.6 testis: 15.2 Expressed in all +RABEP2 FLJ23282, FRA ENSG00000177548 Rabaptin, RAB GTPase binding effector protein 2 16 28904421-28936526 Predicted intracellular proteins Evidence at protein level HPA047641 Approved Supported Vesicles
Cytosol Renal cancer:1.24e-6 (favourable), Head and neck cancer:5.84e-4 (favourable) Expressed in all Expressed in all lymph node: 57.1 Expressed in all +NHLH2 bHLHa34, HEN2, NSCL2 ENSG00000177551 Nescient helix-loop-helix 2 1 115836377-115843917 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055238 Uncertain Approved Nucleoplasm
Nuclear bodies Not detected Tissue enhanced skin: 3.9 cerebral cortex,testis: 0.8 Cell line enriched 11 SCLC-21H: 68.8 +ATOX1 HAH1 ENSG00000177556 Antioxidant 1 copper chaperone 5 151742316-151772532 Predicted intracellular proteins Evidence at protein level HPA055036 Approved Nucleoplasm
Plasma membrane Pancreatic cancer:9.57e-4 (favourable) Expressed in all Expressed in all thyroid gland: 151.5 Expressed in all +FAM187B FLJ25660, TMEM162 ENSG00000177558 Family with sequence similarity 187 member B 19 35224800-35228729 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 202 testis: 44.2 spleen: 0.2 Not detected +TBL1XR1 C21, DC42, FLJ12894, IRA1, TBLR1 ENSG00000177565 Transducin beta like 1 X-linked receptor 1 3 177019340-177228000 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019182 Supported Approved Nucleoplasm Liver cancer:1.08e-7 (unfavourable), Renal cancer:4.25e-5 (unfavourable), Glioma:7.23e-5 (favourable) Expressed in all Expressed in all thyroid gland: 59.4 Expressed in all +SAMD12 FLJ39458 ENSG00000177570 Sterile alpha motif domain containing 12 8 118189459-118621995 Predicted intracellular proteins Evidence at protein level HPA024634 Uncertain Approved Golgi apparatus
Cytosol Renal cancer:1.52e-6 (favourable), Endometrial cancer:1.11e-4 (unfavourable) Mixed Mixed thyroid gland: 14.1 Cell line enhanced SK-BR-3: 25.4 +CD163 M130, MM130, SCARI1 ENSG00000177575 CD163 molecule 12 7470813-7503893 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002432, HPA046404, HPA051974 Enhanced Approved Plasma membrane Ovarian cancer:7.27e-4 (unfavourable) Expressed in all Mixed appendix: 220.1 Cell line enhanced HSkMC: 1.2 +C18orf32 FLJ23458 ENSG00000177576 Chromosome 18 open reading frame 32 18 49477250-49487252 Predicted membrane proteins Evidence at protein level HPA040921 Approved Approved Nucleoplasm
Vesicles Renal cancer:8.89e-9 (favourable) Expressed in all Expressed in all cerebral cortex: 119.6 Expressed in all +PIDD1 DKFZp434D229, LRDD, MGC16925, PIDD ENSG00000177595 P53-induced death domain protein 1 11 799179-809753 Predicted intracellular proteins Evidence at protein level CAB012647, HPA055473 Supported Approved Golgi apparatus
Cytosol Endometrial cancer:3.32e-5 (favourable), Cervical cancer:8.19e-5 (favourable), Renal cancer:1.52e-4 (unfavourable), Head and neck cancer:3.91e-4 (favourable) Expressed in all Mixed bone marrow: 4.6 Cell line enhanced BEWO: 25.3 +ZNF491 FLJ34791 ENSG00000177599 Zinc finger protein 491 19 11797667-11809622 Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Mixed parathyroid gland: 3.6 Mixed +RPLP2 D11S2243E, LP2, MGC71408, P2, RPP2 ENSG00000177600 Ribosomal protein lateral stalk subunit P2 11 809647-812880 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA053635 Approved Approved Mitochondria Renal cancer:2.19e-6 (unfavourable), Liver cancer:9.14e-4 (unfavourable) Expressed in all Expressed in all ovary: 1168.6 Expressed in all +GSG2 haspin ENSG00000177602 Germ cell associated 2, haspin 17 3723903-3726699 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027422, HPA030698 Approved Supported Nucleus Mixed Tissue enhanced testis: 13.2 lymph node: 5.0 Mixed +JUN AP-1, c-Jun ENSG00000177606 Jun proto-oncogene, AP-1 transcription factor subunit 1 58780788-58784327 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003801, CAB007780, HPA059474 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all thyroid gland: 314.6 Cell line enhanced RH-30: 282.2 +CSTF2T CstF-64T, DKFZp434C1013, KIAA0689, tauCstF-64 ENSG00000177613 Cleavage stimulation factor subunit 2 tau variant 10 51695487-51699591 Predicted intracellular proteins Evidence at protein level HPA039216, HPA062021 Approved Enhanced Nucleoplasm Expressed in all Expressed in all parathyroid gland: 37.6 Expressed in all +PGBD5 DKFZp761A0620, FLJ11413 ENSG00000177614 PiggyBac transposable element derived 5 1 230314482-230426371 Predicted intracellular proteins Evidence at protein level HPA065010 Approved Nucleoplasm Glioma:1.20e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 40.1;cervix, uterine: 29.1 adrenal gland: 12.6 Cell line enhanced Daudi: 21.9;NTERA-2: 30.2;RH-30: 15.9;SCLC-21H: 48.7 +C12orf54 MGC35033 ENSG00000177627 Chromosome 12 open reading frame 54 12 48482503-48496512 Predicted intracellular proteins Evidence at transcript level Group enriched Tissue enriched 66 testis: 86.6 tonsil: 1.3 Cell line enhanced HaCaT: 1.2;HBEC3-KT: 3.4;hTERT-HME1: 2.1 +GBA GBA1, GLUC ENSG00000177628 Glucosylceramidase beta 1 155234452-155244699 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006667, CAB037171, CAB037289 Supported Expressed in all Expressed in all parathyroid gland: 276.1 Expressed in all +ACAD9 MGC14452, NPD002 ENSG00000177646 Acyl-CoA dehydrogenase family member 9 3 128879596-128916067 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037716, HPA046720 Supported Enhanced Mitochondria Renal cancer:4.32e-8 (favourable), Liver cancer:3.67e-6 (unfavourable), Endometrial cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all skin: 52.8 Expressed in all +IL17RA CD217, CDw217, hIL-17R, IL-17RA, IL17R ENSG00000177663 Interleukin 17 receptor A 22 17084954-17115694 CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB024996 Enhanced Approved Nucleoplasm
Cytosol Stomach cancer:8.35e-4 (favourable) Expressed in all Mixed bone marrow: 20.6 Cell line enhanced HL-60: 47.4;THP-1: 50.1 +PNPLA2 ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2 ENSG00000177666 Patatin like phospholipase domain containing 2 11 818902-825573 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA055173, HPA062602 Enhanced Nucleoplasm
Lipid droplets Expressed in all Tissue enriched 13 adipose tissue: 420.0 skeletal muscle: 33.4 Expressed in all +MBOAT4 FKSG89, GOAT, OACT4 ENSG00000177669 Membrane bound O-acyltransferase domain containing 4 8 30131824-30144686 Predicted membrane proteins Evidence at protein level HPA044509 Supported Golgi apparatus Tissue enhanced Tissue enhanced fallopian tube: 2.9;stomach: 3.5 gallbladder: 1.6 Cell line enhanced Hep G2: 2.1 +TEX44 C2orf57, MGC35154 ENSG00000177673 Testis expressed 44 2 231592901-231594283 Predicted intracellular proteins Evidence at protein level HPA049917, HPA056433 Enhanced Not detected Tissue enriched 1204 testis: 120.3 all non-specific tissues: 0.0 Not detected +AGTRAP ATRAP ENSG00000177674 Angiotensin II receptor associated protein 1 11736084-11754802 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA044120 Approved Supported Vesicles Liver cancer:6.57e-7 (unfavourable) Expressed in all Expressed in all prostate: 92.6 Expressed in all +CD163L1 CD163B, M160, SCARI2 ENSG00000177675 CD163 molecule like 1 12 7346685-7479897 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015663 Enhanced Approved Nucleoplasm
Centrosome
Cytosol Mixed Tissue enhanced spleen: 43.2 rectum: 24.1 Cell line enhanced U-87 MG: 22.1 +SRRM3 FLJ37078 ENSG00000177679 Serine/arginine repetitive matrix 3 7 76201900-76287288 Predicted intracellular proteins Evidence at protein level HPA019337 Uncertain Approved Plasma membrane
Intermediate filaments
Microtubules Mixed Group enriched 10 adrenal gland: 2.7;cerebral cortex: 8.5;testis: 1.8 stomach: 0.4 Group enriched 12 SCLC-21H: 12.8;SH-SY5Y: 8.5 +THAP5 DKFZp313O1132 ENSG00000177683 THAP domain containing 5 7 108554543-108569750 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043170, HPA051488 Approved Enhanced Nucleus Renal cancer:8.99e-4 (favourable) Expressed in all Expressed in all testis: 46.7 Expressed in all +DEFB114 DEFB-14 ENSG00000177684 Defensin beta 114 6 49960249-49964105 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 734 epididymis: 73.3 all non-specific tissues: 0.0 Not detected +CRACR2B EFCAB4A, MGC45840 ENSG00000177685 Calcium release activated channel regulator 2B 11 826144-831991 Predicted intracellular proteins Evidence at protein level HPA046217 Approved Colorectal cancer:1.81e-5 (unfavourable) Expressed in all Tissue enhanced salivary gland: 120.0 stomach: 56.6 Cell line enhanced HDLM-2: 30.7;SK-BR-3: 92.6 +SUMO4 dJ281H8.4, IDDM5, SMT3H4 ENSG00000177688 Small ubiquitin-like modifier 4 6 149400227-149401292 Predicted intracellular proteins Evidence at protein level HPA042123, HPA048064 Uncertain Approved Nucleoplasm
Nuclear bodies Not detected Not detected liver: 0.6 Not detected +MAGEB10 FLJ32965 ENSG00000177689 MAGE family member B10 X 27807990-27823014 Predicted intracellular proteins Evidence at protein level HPA000611 Uncertain Not detected Tissue enriched 10 testis: 4.6 skin: 0.4 Not detected +DNAJC28 C21orf55, C21orf78 ENSG00000177692 DnaJ heat shock protein family (Hsp40) member C28 21 33485530-33491720 Predicted intracellular proteins Evidence at protein level HPA018003, HPA030076 Approved Mixed Tissue enhanced testis: 8.2 thyroid gland: 4.1 Mixed +OR4F4 OR4F18 ENSG00000177693 Olfactory receptor family 4 subfamily F member 4 15 101922042-101923095 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +NAALADL2 ENSG00000177694 N-acetylated alpha-linked acidic dipeptidase like 2 3 174438573-175810552 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012413, HPA017425, CAB025586 Approved Supported Nucleoplasm Mixed Tissue enhanced parathyroid gland: 28.0 cervix, uterine: 9.9 Cell line enhanced ASC TERT1: 10.1;fHDF/TERT166: 5.0;WM-115: 5.8 +CD151 PETA-3, RAPH, SFA-1, TSPAN24 ENSG00000177697 CD151 molecule (Raph blood group) 11 832843-839831 Blood group antigen proteins, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB002428, HPA011906 Supported Liver cancer:5.58e-4 (unfavourable), Thyroid cancer:6.92e-4 (favourable), Lung cancer:9.46e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 361.3 Mixed +POLR2L hRPB7.6, hsRPB10b, RBP10, RPABC5, RPB10beta, RPB7.6 ENSG00000177700 RNA polymerase II subunit L 11 837356-842545 Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Liver cancer:2.37e-4 (unfavourable), Renal cancer:5.56e-4 (favourable) Expressed in all Expressed in all adipose tissue: 68.0 Expressed in all +FAM20C DKFZp547D065, DMP4, G-CK, IMAGE:4942737 ENSG00000177706 FAM20C, golgi associated secretory pathway kinase 7 192969-260745 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA019823 Approved Nucleoplasm
Golgi apparatus
Cytosol Ovarian cancer:9.40e-6 (unfavourable), Cervical cancer:8.89e-4 (unfavourable) Expressed in all Expressed in all kidney: 38.3 Cell line enhanced HSkMC: 118.8;U-87 MG: 99.8 +NECTIN3 CD113, CDw113, DKFZP566B0846, nectin-3, PPR3, PVRL3, PVRR3 ENSG00000177707 Nectin cell adhesion molecule 3 3 111070071-111275563 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009869, HPA011038 Approved Approved Microtubule organizing center Renal cancer:9.82e-7 (favourable) Expressed in all Tissue enhanced testis: 99.5 thyroid gland: 73.7 Cell line enhanced TIME: 138.4 +SLC35G5 AMAC, AMAC1L2 ENSG00000177710 Solute carrier family 35 member G5 8 11330888-11332208 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Tissue enhanced testis: 1.4 appendix,skin: 0.4 Not detected +ANXA2R AXIIR, C5orf39 ENSG00000177721 Annexin A2 receptor 5 43039081-43043170 Predicted intracellular proteins Evidence at protein level HPA051482 Uncertain Approved Nucleoplasm
Cytosol
Cytoplasmic bodies Renal cancer:6.36e-8 (unfavourable) Expressed in all Tissue enhanced lymph node: 21.9 spleen: 15.4 Cell line enhanced REH: 21.2;U-937: 66.7 +TMEM94 KIAA0195 ENSG00000177728 Transmembrane protein 94 17 75441159-75500090 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008423, HPA050660 Approved Supported Nucleoplasm
Nuclear bodies Pancreatic cancer:2.26e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 54.2 Expressed in all +FLII FLI, Fli1, FLIL, MGC39265 ENSG00000177731 FLII, actin remodeling protein 17 18244836-18258916 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007084, HPA008903, CAB016132 Approved Supported Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all Expressed in all skeletal muscle: 41.2 Expressed in all +SOX12 SOX22 ENSG00000177732 SRY-box 12 20 325595-330224 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055052, HPA061627 Supported Nucleoplasm Liver cancer:6.64e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 10.7 Mixed +HNRNPA0 hnRNPA0, HNRPA0 ENSG00000177733 Heterogeneous nuclear ribonucleoprotein A0 5 137745651-137754376 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036569, HPA059404 Enhanced Enhanced Nucleoplasm Renal cancer:1.99e-4 (favourable), Pancreatic cancer:3.74e-4 (favourable) Expressed in all Expressed in all ovary: 32.8 Expressed in all +YIPF7 FinGER9, FLJ39576 ENSG00000177752 Yip1 domain family member 7 4 44622065-44678556 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA030642 Uncertain Not detected Tissue enriched 42 skeletal muscle: 29.6 esophagus: 0.6 Not detected +MYOZ1 CS-2, FATZ, MYOZ ENSG00000177791 Myozenin 1 10 73631654-73641757 Predicted intracellular proteins Evidence at protein level HPA037848, HPA038437 Enhanced Tissue enhanced Tissue enriched 38 skeletal muscle: 2058.9 esophagus: 54.7 Cell line enriched 25 BEWO: 38.7 +TMEM78 FLJ40168 ENSG00000177800 Transmembrane protein 78 1 229249636-229251810 Predicted membrane proteins Evidence at transcript level HPA042351 Uncertain Not detected Not detected bone marrow,cerebral cortex,skin,testis: 0.3 Not detected +KCNJ10 Kir1.2, Kir4.1 ENSG00000177807 Potassium voltage-gated channel subfamily J member 10 1 159998651-160070483 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA078302 Enhanced Tissue enriched Group enriched 5 cerebral cortex: 124.7;kidney: 30.6 spleen: 14.5 Cell line enhanced Hep G2: 4.5;SK-MEL-30: 1.6;U-266/70: 1.6 +CHID1 FLJ42707, MGC3234 ENSG00000177830 Chitinase domain containing 1 11 867860-915058 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039374 Uncertain Uncertain Nucleoplasm
Intermediate filaments Endometrial cancer:6.76e-4 (favourable) Expressed in all Expressed in all epididymis: 109.0 Expressed in all +PCDHB9 PCDH-BETA9, PCDH3H ENSG00000177839 Protocadherin beta 9 5 141187127-141191541 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA013445 Uncertain Mixed Tissue enhanced cerebral cortex: 7.9 epididymis,ovary: 2.5 Cell line enhanced ASC diff: 7.0;SH-SY5Y: 15.3 +ZNF620 MGC50836 ENSG00000177842 Zinc finger protein 620 3 40505992-40518736 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031452, HPA059383 Uncertain Approved Centrosome Mixed Mixed thyroid gland: 6.0 Mixed +ZNF518A KIAA0335, ZNF518 ENSG00000177853 Zinc finger protein 518A 10 96129715-96205288 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029049 Approved Nucleus Expressed in all Mixed testis: 30.1 Mixed +TMEM187 CXorf12, DXS9878E, ITBA1 ENSG00000177854 Transmembrane protein 187 X 153972327-153983195 Predicted membrane proteins Evidence at transcript level HPA038134 Uncertain Approved Nucleoli
Cytosol Renal cancer:9.14e-8 (favourable) Expressed in all Expressed in all fallopian tube: 11.4 Expressed in all +SVBP CCDC23, MGC45441 ENSG00000177868 Small vasohibin binding protein 1 42807052-42817252 Predicted intracellular proteins Evidence at protein level HPA008507 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:1.18e-4 (unfavourable), Breast cancer:6.33e-4 (favourable) Expressed in all Expressed in all testis: 79.8 Expressed in all +ZNF619 FLJ90764 ENSG00000177873 Zinc finger protein 619 3 40477113-40490236 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045094 Uncertain Approved Nucleoplasm
Intermediate filaments Expressed in all Mixed parathyroid gland: 7.7 Mixed +CCDC184 C12orf68, LOC387856 ENSG00000177875 Coiled-coil domain containing 184 12 48183584-48185926 Predicted intracellular proteins Evidence at protein level HPA039947, HPA041715 Uncertain Approved Mitochondria
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 15.3 adrenal gland: 6.7 Cell line enhanced AF22: 6.1;SH-SY5Y: 4.4;U-2 OS: 2.5;U-87 MG: 3.0 +AP3S1 CLAPS3 ENSG00000177879 Adaptor related protein complex 3 sigma 1 subunit 5 115841481-115914081 Predicted intracellular proteins Evidence at protein level HPA049270 Uncertain Approved Vesicles Renal cancer:9.57e-8 (unfavourable), Pancreatic cancer:1.13e-5 (unfavourable), Breast cancer:1.22e-4 (unfavourable), Glioma:5.30e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 90.3 Expressed in all +GRB2 NCKAP2 ENSG00000177885 Growth factor receptor bound protein 2 17 75318076-75405709 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002589, HPA030749, HPA030750 Approved Supported Nucleus Liver cancer:6.04e-7 (unfavourable) Expressed in all Expressed in all lymph node: 136.5 Expressed in all +ZBTB41 DKFZp686C06120, FLJ36199, FRBZ1, ZNF924 ENSG00000177888 Zinc finger and BTB domain containing 41 1 197153680-197200542 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034841, HPA034842 Uncertain Approved Nucleus
Nuclear membrane
Cytosol Liver cancer:5.86e-4 (unfavourable) Expressed in all Mixed thyroid gland: 12.7 Expressed in all +UBE2N MGC8489, UBC13, UbcH-ben ENSG00000177889 Ubiquitin conjugating enzyme E2 N 12 93405673-93442262 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044976 Enhanced Supported Nucleus
Nucleoli fibrillar center Liver cancer:2.41e-4 (unfavourable) Expressed in all Expressed in all testis: 253.6 Expressed in all +ARL6IP6 MGC33864 ENSG00000177917 ADP ribosylation factor like GTPase 6 interacting protein 6 2 152717893-152761253 Predicted membrane proteins Evidence at protein level HPA014743 Enhanced Approved Nuclear membrane
Cytosol Liver cancer:1.73e-4 (unfavourable), Renal cancer:2.14e-4 (unfavourable) Expressed in all Mixed placenta: 7.5 Expressed in all +ZNF354C KID3 ENSG00000177932 Zinc finger protein 354C 5 179060415-179083537 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030904 Uncertain Supported Nuclear membrane
Cytosol Mixed Mixed ovary: 9.2 Cell line enhanced AN3-CA: 17.5 +CAPZA3 CAPPA3, Gsg3 ENSG00000177938 Capping actin protein of muscle Z-line alpha subunit 3 12 18738101-18739187 Predicted intracellular proteins Evidence at protein level HPA038688 Enhanced Not detected Tissue enriched 100 testis: 281.4 skin: 2.8 Not detected +MAMDC4 AEGP, DKFZp434M1411 ENSG00000177943 MAM domain containing 4 9 136850943-136860799 Predicted membrane proteins Evidence at protein level CAB026377, HPA059977 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:1.88e-6 (favourable) Expressed in all Mixed spleen: 5.6 Cell line enhanced BEWO: 16.2 +CENPBD1 MGC16385 ENSG00000177946 CENPB DNA-binding domain containing 1 16 89969791-89972534 Predicted intracellular proteins Evidence at transcript level HPA052759, HPA060522 Uncertain Approved Nucleoli
Vesicles Renal cancer:5.27e-11 (favourable) Expressed in all Mixed parathyroid gland: 11.1 Expressed in all +ODF3 CT135, hSHIPPO, SHIPPO1 ENSG00000177947 Outer dense fiber of sperm tails 3 11 196738-200261 Predicted intracellular proteins Evidence at protein level HPA038919, HPA039241 Enhanced Not detected Tissue enriched 94 testis: 9.4 all non-specific tissues: 0.0 Not detected +BET1L GOLIM3, GS15 ENSG00000177951 Bet1 golgi vesicular membrane trafficking protein like 11 167784-207428 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039819 Approved Approved Nucleus
Golgi apparatus Liver cancer:2.20e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 75.0 Expressed in all +RPS27 MPS-1, MPS1, S27 ENSG00000177954 Ribosomal protein S27 1 153990759-153992150 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA066851 Approved Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:4.86e-7 (unfavourable), Breast cancer:9.69e-4 (favourable) Expressed in all Expressed in all ovary: 12000.9 Expressed in all +RIC8A synembryn, synembryn-A ENSG00000177963 RIC8 guanine nucleotide exchange factor A 11 207511-215113 Predicted intracellular proteins Evidence at protein level HPA041491, CAB046012 Approved Supported Cytosol Liver cancer:1.11e-6 (unfavourable), Endometrial cancer:8.60e-4 (favourable) Expressed in all Expressed in all smooth muscle: 72.1 Expressed in all +IMP3 BRMS2, C15orf12, FLJ10968, MRPS4 ENSG00000177971 IMP3, U3 small nucleolar ribonucleoprotein 15 75639085-75648706 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA060955, HPA061177 Enhanced Nucleus
Nucleoli Expressed in all Expressed in all spleen: 47.6 Expressed in all +ASB8 FLJ21255, MGC5540 ENSG00000177981 Ankyrin repeat and SOCS box containing 8 12 48147788-48181213 Predicted intracellular proteins Evidence at protein level HPA003299 Approved Renal cancer:6.57e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 98.2 Expressed in all +LCN15 PRO6093, UNQ2541 ENSG00000177984 Lipocalin 15 9 136759634-136766255 Predicted secreted proteins Evidence at protein level HPA060584 Enhanced Tissue enriched Tissue enhanced duodenum: 12.1;seminal vesicle: 5.0;small intestine: 4.0 colon: 2.8 Group enriched 14 Hep G2: 11.9;SCLC-21H: 3.0 +ODF3B ENSG00000177989 Outer dense fiber of sperm tails 3B 22 50529710-50532580 Predicted intracellular proteins Evidence at protein level HPA062837 Enhanced Renal cancer:2.65e-5 (unfavourable), Endometrial cancer:2.84e-4 (favourable), Head and neck cancer:4.89e-4 (favourable) Expressed in all Tissue enhanced fallopian tube: 75.0 appendix: 36.7 Cell line enhanced Karpas-707: 29.6;U-266/70: 44.1 +DPY19L2 FLJ32949, SPATA34 ENSG00000177990 Dpy-19 like 2 12 63558913-63668939 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA071264 Approved Nucleus
Mitochondria Mixed Tissue enriched 8 testis: 112.0 parathyroid gland: 14.4 Mixed +SPATA31E1 C9orf79, FAM75E1, FLJ35866 ENSG00000177992 SPATA31 subfamily E member 1 9 87882826-87888899 Predicted membrane proteins Evidence at protein level HPA024253 Enhanced Not detected Tissue enriched 99 testis: 9.9 all non-specific tissues: 0.0 Cell line enhanced ASC TERT1: 1.1;SCLC-21H: 1.6 +C2orf73 FLJ40298 ENSG00000177994 Chromosome 2 open reading frame 73 2 54330034-54383742 Predicted intracellular proteins Evidence at transcript level HPA055221, HPA059596 Uncertain Not detected Tissue enriched 7 testis: 83.7 fallopian tube: 12.2 Not detected +GPR150 PGR11 ENSG00000178015 G protein-coupled receptor 150 5 95620078-95622142 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA026635 Uncertain Mixed Tissue enhanced cerebral cortex: 1.3;parathyroid gland: 2.0 pancreas: 1.0 Cell line enhanced ASC diff: 1.0;SiHa: 1.3;TIME: 2.2 +TSPYL6 ENSG00000178021 TSPY like 6 2 54253184-54256272 Predicted intracellular proteins Evidence at protein level HPA034699, HPA034700 Enhanced Approved Nucleoli
Centrosome
Cytosol Tissue enriched Tissue enriched 390 testis: 39.0 all non-specific tissues: 0.0 Cell line enriched 73 K-562: 7.3 +LRRC75B C22orf36, FAM211B, MGC131773 ENSG00000178026 Leucine rich repeat containing 75B 22 24585620-24593208 Predicted intracellular proteins Evidence at transcript level HPA002540 Uncertain Approved Nucleus
Cytosol Expressed in all Tissue enhanced testis: 2.2 cerebral cortex: 1.3 Cell line enhanced SH-SY5Y: 4.4 +DMAP1 DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, MEAF2, SWC4 ENSG00000178028 DNA methyltransferase 1 associated protein 1 1 44213455-44220681 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028419, CAB033018 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:1.44e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 40.4 Expressed in all +ADAMTSL1 ADAMTSR1, C9orf94, FLJ35283 ENSG00000178031 ADAMTS like 1 9 17906563-18910950 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA057437 Uncertain Mixed Tissue enhanced endometrium: 24.1 smooth muscle: 18.7 Cell line enhanced ASC TERT1: 81.0;hTEC/SVTERT24-B: 62.6;TIME: 164.0;U-138 MG: 93.4 +FAM26E C6orf188, dJ493F7.3, MGC45451 ENSG00000178033 Family with sequence similarity 26 member E 6 116511646-116524792 Predicted membrane proteins Evidence at protein level HPA034969, HPA034970 Uncertain Approved Golgi apparatus Mixed Mixed placenta: 6.4 Cell line enhanced TIME: 7.3 +IMPDH2 ENSG00000178035 Inosine monophosphate dehydrogenase 2 3 49024325-49029408 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001400, CAB020717 Approved Enhanced Cytosol
Rods & Rings Liver cancer:3.22e-4 (unfavourable) Expressed in all Expressed in all ovary: 422.5 Expressed in all +ALS2CL DKFZp686I0110, FLJ36525, RN49018 ENSG00000178038 ALS2 C-terminal like 3 46668997-46693704 Predicted intracellular proteins Evidence at protein level CAB046465, HPA048301 Uncertain Endometrial cancer:8.10e-4 (unfavourable) Expressed in all Tissue enhanced skin: 38.8 esophagus: 15.8 Cell line enhanced CAPAN-2: 30.1;HaCaT: 16.9;HBEC3-KT: 25.9;hTCEpi: 18.1;RT4: 15.4 +MLF1 ENSG00000178053 Myeloid leukemia factor 1 3 158571163-158607252 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Endometrial cancer:2.15e-5 (unfavourable), Stomach cancer:5.54e-4 (unfavourable) Mixed Tissue enriched 7 testis: 671.8 fallopian tube: 97.0 Cell line enhanced A-431: 71.8 +PRSS42 TESSP2 ENSG00000178055 Protease, serine 42 3 46829542-46834095 Enzymes, Predicted secreted proteins Evidence at transcript level HPA046925 Uncertain Not detected Group enriched 6 epididymis: 4.8;heart muscle: 8.8;parathyroid gland: 3.1;skeletal muscle: 8.4;testis: 2.0;thyroid gland: 1.9 breast,cervix, uterine,prostate,seminal vesicle: 0.7 Cell line enhanced NTERA-2: 1.0 +NDUFAF3 2P1, C3orf60, DKFZP564J0123, E3-3, MGC10527 ENSG00000178057 NADH:ubiquinone oxidoreductase complex assembly factor 3 3 49020459-49023495 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035376, HPA035377 Enhanced Renal cancer:1.86e-5 (favourable) Expressed in all Expressed in all testis: 287.5 Expressed in all +C2orf69 FLJ38973 ENSG00000178074 Chromosome 2 open reading frame 69 2 199911256-199955935 Predicted secreted proteins Evidence at protein level HPA045225 Uncertain Expressed in all Expressed in all testis: 26.6 Expressed in all +GRAMD1C DKFZp434C0328 ENSG00000178075 GRAM domain containing 1C 3 113828182-113947174 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012316 Approved Uncertain Plasma membrane
Cytosol Renal cancer:4.22e-15 (favourable) Mixed Mixed testis: 28.1 Cell line enhanced CAPAN-2: 11.4;HUVEC TERT2: 8.3 +STAP2 BKS, STAP-2 ENSG00000178078 Signal transducing adaptor family member 2 19 4324043-4342786 Predicted intracellular proteins Evidence at protein level HPA002375, HPA027761 Approved Endometrial cancer:3.03e-5 (favourable), Cervical cancer:2.76e-4 (favourable), Urothelial cancer:4.13e-4 (favourable) Expressed in all Mixed small intestine: 79.8 Cell line enhanced A-431: 75.0;MCF7: 77.8;RT4: 107.6 +HTR3C ENSG00000178084 5-hydroxytryptamine receptor 3C 3 184053047-184060671 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced lung: 1.9 duodenum: 0.4 Not detected +TSSK6 CT72, FLJ24002, SSTK ENSG00000178093 Testis specific serine kinase 6 19 19512418-19515685 Enzymes, Predicted intracellular proteins Evidence at protein level Expressed in all Tissue enriched 24 testis: 18.6 duodenum,spleen: 0.7 Cell line enhanced BEWO: 3.9 +BOLA1 CGI-143 ENSG00000178096 BolA family member 1 1 149887890-149900798 Predicted secreted proteins Evidence at protein level HPA007005 Approved Liver cancer:5.88e-4 (unfavourable), Ovarian cancer:6.41e-4 (favourable) Expressed in all Expressed in all duodenum: 15.6 Cell line enhanced MCF7: 42.0 +PDE4DIP CMYA2, KIAA0454, KIAA0477, MMGL ENSG00000178104 Phosphodiesterase 4D interacting protein 1 148808181-149048286 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008162, HPA012678 Uncertain Supported Golgi apparatus Expressed in all Expressed in all skeletal muscle: 766.6 Expressed in all +DDX10 HRH-J8 ENSG00000178105 DEAD-box helicase 10 11 108665025-108940930 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA004691 Approved Approved Nucleoli Renal cancer:2.14e-5 (favourable), Liver cancer:2.52e-5 (unfavourable), Pancreatic cancer:5.75e-4 (unfavourable) Expressed in all Expressed in all testis: 29.2 Expressed in all +GOLGA8Q ENSG00000178115 Golgin A8 family member Q 15 30552078-30562501 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 7 thyroid gland: 20.9 parathyroid gland: 2.8 Group enriched 6 THP-1: 4.4;U-937: 7.0 +PPP1R42 dtr, LRRC67, TLLR ENSG00000178125 Protein phosphatase 1 regulatory subunit 42 8 66964099-67056604 Predicted intracellular proteins Evidence at transcript level HPA024313, HPA027983, HPA028628 Uncertain Mixed Group enriched 20 fallopian tube: 7.9;testis: 15.6 lung: 0.6 Not detected +NDUFV2 CI-24k ENSG00000178127 NADH:ubiquinone oxidoreductase core subunit V2 18 9102630-9134345 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003404, HPA077896 Supported Approved Supported Mitochondria Expressed in all Expressed in all skeletal muscle: 190.8 Expressed in all +DALRD3 FLJ10496 ENSG00000178149 DALR anticodon binding domain containing 3 3 49015488-49022293 Predicted intracellular proteins Evidence at protein level HPA036862 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:2.79e-5 (favourable), Endometrial cancer:9.03e-4 (favourable) Expressed in all Expressed in all fallopian tube: 59.2 Expressed in all +ZNF114 MGC17986 ENSG00000178150 Zinc finger protein 114 19 48270102-48287608 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA025019, HPA029553 Uncertain Approved Nucleus
Cytosol Head and neck cancer:3.29e-4 (unfavourable) Mixed Tissue enhanced thyroid gland: 10.3 parathyroid gland: 3.6 Cell line enhanced BEWO: 21.9;Hep G2: 18.9 +ZNF518B KIAA1729 ENSG00000178163 Zinc finger protein 518B 4 10439874-10457410 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031215, HPA031216 Approved Approved Nucleus Mixed Mixed testis: 16.9 Mixed +AMER3 FAM123C, FLJ38377 ENSG00000178171 APC membrane recruitment protein 3 2 130755435-130768134 Predicted intracellular proteins Evidence at protein level HPA045593, HPA054230 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Tissue enhanced Tissue enriched 9 cerebral cortex: 7.0 adrenal gland: 0.8 Cell line enriched 6 SCLC-21H: 12.2 +SPINK6 BUSI2, MGC21394, UNQ844 ENSG00000178172 Serine peptidase inhibitor, Kazal type 6 5 148202794-148215137 Predicted secreted proteins Evidence at protein level HPA011039 Uncertain Head and neck cancer:7.16e-4 (favourable) Group enriched Not detected epididymis: 0.9 Group enriched 73 HeLa: 1936.6;SiHa: 1473.3 +ZNF366 FLJ39796 ENSG00000178175 Zinc finger protein 366 5 72442652-72507727 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023128, HPA023526 Uncertain Mixed Mixed placenta: 10.2 Cell line enhanced HUVEC TERT2: 1.0;TIME: 1.1 +LCORL FLJ30696, MLR1 ENSG00000178177 Ligand dependent nuclear receptor corepressor like 4 17841199-18021876 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028794, HPA028795, HPA060033 Uncertain Supported Nucleoplasm
Nuclear membrane Colorectal cancer:9.65e-4 (favourable) Expressed in all Mixed testis: 12.1 Expressed in all +PARD6G PAR-6G, PAR6gamma ENSG00000178184 Par-6 family cell polarity regulator gamma 18 80157232-80247546 Predicted intracellular proteins Evidence at protein level HPA047017 Uncertain Approved Plasma membrane Liver cancer:3.19e-4 (unfavourable) Expressed in all Tissue enhanced skin: 44.9 thyroid gland: 30.0 Cell line enhanced HMC-1: 31.8;U-2 OS: 30.2 +ZNF454 FLJ37444 ENSG00000178187 Zinc finger protein 454 5 178941191-178966433 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA024556 Uncertain Mixed Mixed testis: 4.0 Cell line enhanced AF22: 1.0;EFO-21: 1.9;HHSteC: 1.3;HSkMC: 1.3;NTERA-2: 1.5;SH-SY5Y: 1.1 +SH2B1 FLJ30542, SH2B ENSG00000178188 SH2B adaptor protein 1 16 28846600-28874212 Predicted intracellular proteins Evidence at protein level HPA076175 Approved Vesicles Renal cancer:2.81e-6 (favourable), Urothelial cancer:1.60e-4 (favourable), Pancreatic cancer:4.38e-4 (favourable), Lung cancer:9.40e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 105.8 Expressed in all +ZC3H12D C6orf95, dJ281H8.1, MCPIP4 ENSG00000178199 Zinc finger CCCH-type containing 12D 6 149446795-149485061 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036897 Uncertain Supported Nucleoplasm
Cytoplasmic bodies Mixed Tissue enhanced appendix: 9.6;lymph node: 11.5;tonsil: 11.6 spleen: 5.9 Cell line enhanced Daudi: 5.7;HDLM-2: 31.7;REH: 6.4 +VN1R1 V1RL1, VNR19I1, ZVNH1, ZVNR1 ENSG00000178201 Vomeronasal 1 receptor 1 19 57454790-57457142 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level HPA062209 Uncertain Nucleus
Vesicles Mixed Mixed epididymis: 2.7 Cell line enhanced HEK 293: 2.6;U-266/70: 1.9;U-266/84: 2.3 +KDELC2 MGC33424 ENSG00000178202 KDEL motif containing 2 11 108472105-108498432 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039315, HPA039817, HPA066134 Uncertain Supported Nucleoplasm
Vesicles Urothelial cancer:6.27e-5 (unfavourable), Liver cancer:1.45e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 62.2 Mixed +PLEC EBS1, PCN, PLEC1, PLTN ENSG00000178209 Plectin 8 143915147-143976734 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003847, HPA025967, HPA029906 Enhanced Enhanced Intermediate filaments
Focal adhesion sites
Cytosol Renal cancer:7.98e-6 (unfavourable), Colorectal cancer:4.29e-4 (unfavourable), Lung cancer:5.33e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 94.8 Expressed in all +SH2D4B ENSG00000178217 SH2 domain containing 4B 10 80537902-80646560 Predicted intracellular proteins Evidence at protein level HPA040022 Uncertain Not detected Not detected epididymis: 0.5 Cell line enriched 64 REH: 17.4 +RNF212 FLJ38841, LOC285498 ENSG00000178222 Ring finger protein 212 4 1056250-1113562 Predicted intracellular proteins Evidence at transcript level HPA057527 Uncertain Cervical cancer:1.39e-4 (favourable) Mixed Mixed thyroid gland: 5.8 Cell line enhanced A-431: 11.1;HeLa: 25.6;SiHa: 24.3 +PRSS36 FLJ90661 ENSG00000178226 Protease, serine 36 16 31138925-31150094 Enzymes, Predicted secreted proteins Evidence at protein level HPA036079 Uncertain Cervical cancer:2.97e-7 (favourable) Mixed Mixed skin: 1.2 Cell line enhanced HeLa: 1.4 +ZNF543 DKFZp434H055 ENSG00000178229 Zinc finger protein 543 19 57320509-57330776 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029736, HPA057665 Uncertain Approved Nuclear speckles
Cytosol Renal cancer:2.03e-5 (favourable) Expressed in all Mixed ovary: 6.0 Mixed +TMEM151B bA444E17.5, C6orf137, TMEM193 ENSG00000178233 Transmembrane protein 151B 6 44270466-44307506 Predicted membrane proteins Evidence at transcript level HPA055167 Uncertain Tissue enhanced Tissue enriched 10 cerebral cortex: 40.0 adrenal gland: 3.9 Cell line enriched 5 SCLC-21H: 33.6 +GALNT11 GalNAc-T11 ENSG00000178234 Polypeptide N-acetylgalactosaminyltransferase 11 7 152025674-152122347 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA039330 Uncertain Renal cancer:2.24e-6 (favourable), Glioma:8.42e-4 (unfavourable) Expressed in all Expressed in all kidney: 242.9 Mixed +SLITRK1 KIAA1910, LRRC12 ENSG00000178235 SLIT and NTRK like family member 1 13 83877205-83882393 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA012414 Enhanced Tissue enriched Tissue enriched 81 cerebral cortex: 23.8 adrenal gland,cervix, uterine,pancreas,seminal vesicle: 0.2 Cell line enhanced A-431: 2.6;AF22: 1.1 +WDR6 ENSG00000178252 WD repeat domain 6 3 49007062-49015953 Predicted intracellular proteins Evidence at protein level HPA042622 Approved Supported Plasma membrane
Cytosol Liver cancer:2.97e-6 (unfavourable), Renal cancer:4.52e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 204.8 Expressed in all +PRM3 ENSG00000178257 Protamine 3 16 11273218-11273641 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 23 testis: 42.3 bone marrow: 1.8 Cell line enhanced TIME: 3.0 +TNP2 TP2 ENSG00000178279 Transition protein 2 16 11267748-11269533 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 387 testis: 38.6 all non-specific tissues: 0.0 Not detected +SPAG11A EDDM2A, HE2 ENSG00000178287 Sperm associated antigen 11A 8 7847876-7868867 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023842 Supported Not detected Tissue enriched 12587 epididymis: 6263.0 fallopian tube,seminal vesicle: 0.4 Group enriched 8 BEWO: 1.8;NB-4: 5.5;RPMI-8226: 1.4;SH-SY5Y: 1.3 +GEN1 FLJ40869, Gen ENSG00000178295 GEN1, Holliday junction 5' flap endonuclease 2 17753858-17788941 Predicted intracellular proteins Evidence at protein level HPA020078, HPA021141 Uncertain Approved Nucleoplasm Endometrial cancer:1.68e-4 (unfavourable) Expressed in all Mixed lymph node: 15.5 Expressed in all +TMPRSS9 ENSG00000178297 Transmembrane protease, serine 9 19 2389771-2426239 Enzymes, Predicted membrane proteins Evidence at protein level HPA051483 Uncertain Mixed Tissue enhanced spleen: 2.3;testis: 1.7 skin: 0.8 Cell line enhanced Karpas-707: 1.8;U-266/70: 1.7 +AQP11 ENSG00000178301 Aquaporin 11 11 77589391-77610355 Predicted membrane proteins, Transporters Evidence at protein level HPA042879 Approved Approved Nucleoplasm
Vesicles Ovarian cancer:9.89e-4 (favourable) Mixed Tissue enhanced duodenum: 24.1;small intestine: 23.1 adrenal gland: 10.0 Cell line enhanced Hep G2: 7.7 +TMEM11 C17orf35, PM1, PMI ENSG00000178307 Transmembrane protein 11 17 21197280-21214624 Predicted membrane proteins Evidence at protein level HPA051795, HPA062854 Uncertain Supported Mitochondria Expressed in all Mixed skeletal muscle: 3.6 Mixed +ZNF354B FLJ25008, KID2 ENSG00000178338 Zinc finger protein 354B 5 178859953-178888122 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA029056 Approved Approved Nucleoplasm Renal cancer:1.30e-5 (unfavourable), Head and neck cancer:9.52e-4 (favourable) Expressed in all Expressed in all placenta: 19.9 Mixed +KCNG2 KCNF2, Kv6.2 ENSG00000178342 Potassium voltage-gated channel modifier subfamily G member 2 18 79863668-79900184 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA048628 Approved Not detected Not detected cerebral cortex: 0.4 Not detected +SHISA3 hShisa3 ENSG00000178343 Shisa family member 3 4 42397839-42402487 Predicted membrane proteins Evidence at protein level HPA054754 Approved Lipid droplets
Cytosol Mixed Tissue enhanced kidney: 25.1 lymph node: 8.7 Group enriched 6 AN3-CA: 231.0;PC-3: 134.3 +OR2D3 ENSG00000178358 Olfactory receptor family 2 subfamily D member 3 11 6920974-6922043 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA052551 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +CALML3 CLP ENSG00000178363 Calmodulin like 3 10 5524009-5526771 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010070, HPA044999 Approved Group enriched Tissue enhanced esophagus: 165.7;skin: 42.6 tonsil: 22.4 Group enriched 6 A-431: 12.2;hTCEpi: 3.8;RPMI-8226: 2.6 +CALML5 CLSP ENSG00000178372 Calmodulin like 5 10 5498697-5499555 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA040725 Enhanced Approved Plasma membrane
Cytosol Head and neck cancer:2.59e-5 (favourable) Group enriched Group enriched 8 salivary gland: 260.7;skin: 650.6 breast: 55.6 Cell line enriched 24 A-431: 355.7 +ZFAND2A AIRAP ENSG00000178381 Zinc finger AN1-type containing 2A 7 1152071-1160759 Predicted intracellular proteins Evidence at transcript level HPA019469 Approved Renal cancer:5.47e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 50.0 Expressed in all +PLEKHM3 DAPR, PLEKHM1L ENSG00000178385 Pleckstrin homology domain containing M3 2 207821288-208025560 Predicted intracellular proteins Evidence at protein level HPA035046 Uncertain Approved Vesicles
Cytosol Mixed Mixed parathyroid gland: 18.9 Mixed +ZNF223 ENSG00000178386 Zinc finger protein 223 19 44051367-44067991 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067823 Approved Nucleus
Mitochondria Mixed Mixed prostate,thyroid gland: 10.6 Cell line enhanced RT4: 18.6 +HTR1A 5-HT1A, ADRB2RL1, ADRBRL1 ENSG00000178394 5-hydroxytryptamine receptor 1A 5 63960356-63962507 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018073 Uncertain Not detected Group enriched 10 cerebral cortex: 1.9;ovary: 3.9 testis: 0.2 Group enriched 16 NTERA-2: 1.6;SCLC-21H: 1.5 +CCDC185 C1orf65, FLJ35728 ENSG00000178395 Coiled-coil domain containing 185 1 223393417-223395470 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 198 testis: 25.1 cerebral cortex: 0.1 Not detected +FAM220A ACPIN1, C7orf70, MGC12966, SIPAR ENSG00000178397 Family with sequence similarity 220 member A 7 6329409-6348981 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA055050 Approved Vesicles Liver cancer:5.17e-6 (unfavourable), Thyroid cancer:3.47e-4 (unfavourable) Expressed in all Expressed in all testis: 102.3 Expressed in all +DNAJC22 FLJ13236, wus ENSG00000178401 DnaJ heat shock protein family (Hsp40) member C22 12 49346917-49357546 Predicted membrane proteins Evidence at protein level HPA039953 Approved Vesicles Endometrial cancer:4.56e-5 (favourable), Melanoma:7.54e-4 (unfavourable) Mixed Mixed thyroid gland: 17.9 Cell line enhanced CACO-2: 24.1;EFO-21: 28.4;MCF7: 19.7;T-47d: 21.2 +NEUROG2 Atoh4, bHLHa8, Math4A, ngn-2, NGN2 ENSG00000178403 Neurogenin 2 4 112513516-112516172 Predicted intracellular proteins, Transcription factors Evidence at transcript level CAB012342 Uncertain Tissue enhanced Tissue enhanced testis: 1.5 cerebral cortex: 0.4 Cell line enriched 8 SH-SY5Y: 216.2 +CEP295NL DDC8, KIAA1731NL ENSG00000178404 CEP295 N-terminal like 17 78870910-78903217 Predicted intracellular proteins Evidence at transcript level HPA023609, HPA024619, HPA025717 Uncertain Approved Vesicles Not detected Tissue enriched 46 testis: 40.5 bone marrow: 0.8 Cell line enhanced BEWO: 1.4;U-2 OS: 2.0 +BEND3 KIAA1553 ENSG00000178409 BEN domain containing 3 6 107065182-107115269 Predicted intracellular proteins Evidence at protein level HPA017891, HPA062067 Uncertain Approved Nucleoplasm Expressed in all Mixed testis: 2.7 Mixed +NT5DC1 dJ486I3.1, MGC24302, NT5C2L1 ENSG00000178425 5'-nucleotidase domain containing 1 6 116100849-116249497 Predicted intracellular proteins Evidence at protein level HPA030352 Uncertain Renal cancer:7.49e-7 (favourable), Colorectal cancer:2.61e-4 (favourable) Expressed in all Expressed in all thyroid gland: 47.2 Expressed in all +GLDC GCSP, NKH ENSG00000178445 Glycine decarboxylase 9 6532464-6645783 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002318, HPA052887 Enhanced Supported Nucleus
Mitochondria Endometrial cancer:5.24e-5 (unfavourable), Renal cancer:3.50e-4 (favourable) Tissue enhanced Tissue enhanced kidney: 30.3;liver: 19.9;placenta: 20.1 cerebral cortex: 10.6 Cell line enhanced BEWO: 206.9;RPTEC TERT1: 67.4 +COX14 C12orf62, MGC14288 ENSG00000178449 COX14, cytochrome c oxidase assembly factor 12 50111979-50120457 Disease related genes, Predicted membrane proteins Evidence at protein level HPA044618, HPA062014 Approved Supported Mitochondria Melanoma:7.90e-4 (unfavourable) Expressed in all Expressed in all kidney: 86.5 Expressed in all +MCMDC2 C8orf45, FLJ25692 ENSG00000178460 Minichromosome maintenance domain containing 2 8 66870749-66922048 Predicted intracellular proteins Evidence at protein level HPA026522 Approved Actin filaments Not detected Tissue enriched 6 testis: 21.6 ovary: 3.7 Mixed +TUBAL3 FLJ21665 ENSG00000178462 Tubulin alpha like 3 10 5393098-5404830 Predicted intracellular proteins Evidence at protein level HPA045900, HPA063394 Uncertain Tissue enhanced Tissue enhanced duodenum: 24.4;small intestine: 31.0 colon: 11.8 Group enriched 6 HEL: 11.9;K-562: 3.8 +P4HTM EGLN4, FLJ20262, HIFPH4, P4H-TM, PH-4, PH4, PHD4 ENSG00000178467 Prolyl 4-hydroxylase, transmembrane 3 48989886-49007154 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007199 Supported Uncertain Vesicles
Cytosol Renal cancer:3.28e-5 (favourable), Endometrial cancer:8.18e-4 (favourable) Expressed in all Expressed in all fallopian tube: 50.0 Mixed +UCN3 SPC, UCNIII ENSG00000178473 Urocortin 3 10 5365009-5374692 Predicted secreted proteins Evidence at protein level HPA038281 Uncertain Group enriched Tissue enhanced duodenum: 9.3;small intestine: 7.5 stomach: 3.6 Cell line enriched 10 SCLC-21H: 1.5 +DTX3 FLJ34766, RNF154 ENSG00000178498 Deltex E3 ubiquitin ligase 3 12 57604622-57609804 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059654 Approved Approved Nucleus
Nucleoli
Golgi apparatus Pancreatic cancer:1.44e-4 (favourable), Lung cancer:9.87e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 102.8 Mixed +KLHL11 FLJ10572 ENSG00000178502 Kelch like family member 11 17 41853545-41865431 Predicted secreted proteins Evidence at protein level HPA023021, HPA054269 Uncertain Mixed Tissue enhanced testis: 22.4 cerebral cortex: 10.7 Mixed +AMBN ENSG00000178522 Ameloblastin 4 70592256-70607288 Disease related genes, Predicted secreted proteins Evidence at protein level Group enriched Not detected cerebral cortex: 0.3 Cell line enriched 9 HEK 293: 6.2 +CTXN1 FLJ25968 ENSG00000178531 Cortexin 1 19 7924485-7926166 Predicted membrane proteins Evidence at transcript level HPA016669 Uncertain Approved Nucleoplasm
Plasma membrane
Cell Junctions Expressed in all Tissue enhanced cerebral cortex: 100.4 endometrium: 22.7 Cell line enhanced AN3-CA: 86.1;NTERA-2: 70.2;SCLC-21H: 63.8;SH-SY5Y: 96.5 +SLC25A20 CAC, CACT ENSG00000178537 Solute carrier family 25 member 20 3 48856931-48898993 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA016862, HPA029863 Approved Supported Mitochondria
Cytosol Expressed in all Expressed in all liver: 70.9 Cell line enhanced RPMI-8226: 88.8 +CA8 CALS, CARP ENSG00000178538 Carbonic anhydrase 8 8 60187347-60281412 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024748, CAB025545, CAB047309 Supported Pancreatic cancer:5.79e-5 (favourable) Mixed Tissue enriched 6 parathyroid gland: 105.5 epididymis: 17.4 Cell line enhanced HEK 293: 15.9;K-562: 29.2;NB-4: 11.8 +CD28 ENSG00000178562 CD28 molecule 2 203706475-203738912 CD markers, Predicted membrane proteins Evidence at protein level HPA070003 Enhanced Mixed Tissue enhanced lymph node: 32.4;placenta: 20.9 appendix: 18.6 Group enriched 12 Karpas-707: 257.5;RPMI-8226: 118.2;U-266/70: 222.7;U-266/84: 196.1 +EPM2AIP1 FLJ11207, KIAA0766 ENSG00000178567 EPM2A interacting protein 1 3 36985043-36993168 Predicted intracellular proteins Evidence at protein level Cervical cancer:2.70e-4 (favourable) Expressed in all Expressed in all thyroid gland: 35.7 Mixed +ERBB4 ALS19, HER4 ENSG00000178568 Erb-b2 receptor tyrosine kinase 4 2 211375717-212538841 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB000276, HPA012016, CAB025522 Enhanced Tissue enhanced Tissue enhanced fallopian tube: 17.8 cerebral cortex: 7.6 Group enriched 5 AF22: 6.8;EFO-21: 4.8;HEK 293: 3.5;RPTEC TERT1: 4.2;SCLC-21H: 3.7;T-47d: 4.8 +MAF c-MAF ENSG00000178573 MAF bZIP transcription factor 16 79585843-79600714 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB010296, HPA028289 Approved Renal cancer:3.74e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 149.6 small intestine: 91.3 Group enriched 9 Karpas-707: 148.6;RPMI-8226: 242.2 +CTNNBIP1 ICAT, MGC15093 ENSG00000178585 Catenin beta interacting protein 1 1 9848276-9910336 Predicted intracellular proteins Evidence at protein level HPA042617 Approved Plasma membrane
Cell Junctions
Mitochondria Endometrial cancer:5.68e-6 (favourable) Expressed in all Expressed in all skin: 289.6 Expressed in all +OR6B3 OR6B3P, OR6B3Q ENSG00000178586 Olfactory receptor family 6 subfamily B member 3 2 240045077-240046072 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047529 Uncertain Not detected Tissue enhanced epididymis: 1.9 testis: 0.7 Not detected +DEFB125 DEFB-25 ENSG00000178591 Defensin beta 125 20 87250-97094 Predicted secreted proteins Evidence at transcript level HPA043095 Uncertain Not detected Group enriched 11 epididymis: 1.3;seminal vesicle: 1.5 testis: 0.1 Not detected +PSAPL1 ENSG00000178597 Prosaposin-like 1 (gene/pseudogene) 4 7430294-7434973 Predicted secreted proteins Evidence at protein level HPA038013, HPA038482 Approved Enhanced Cytosol Mixed Group enriched 7 skin: 52.7;stomach: 36.5 breast: 6.4 Cell line enhanced CACO-2: 13.5;HaCaT: 3.9;hTCEpi: 3.9;RPMI-8226: 16.8 +OTOS OTOSP ENSG00000178602 Otospiralin 2 240139026-240144562 Predicted secreted proteins Evidence at transcript level Group enriched Tissue enriched 16 thyroid gland: 74.1 cerebral cortex: 4.6 Not detected +GTPBP6 FLJ20977, PGPL ENSG00000178605 GTP binding protein 6 (putative) X 304529-318819 Predicted intracellular proteins Evidence at protein level CAB034924, HPA035467, HPA055418 Approved Uncertain Mitochondria Pancreatic cancer:1.71e-4 (favourable), Liver cancer:8.87e-4 (unfavourable) Expressed in all Expressed in all spleen: 26.1 Expressed in all +ERN1 IRE1, IRE1P ENSG00000178607 Endoplasmic reticulum to nucleus signaling 1 17 64039142-64130819 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009495, HPA027730 Supported Renal cancer:1.68e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 53.4 Cell line enhanced Karpas-707: 74.5;U-266/70: 74.0 +GPR35 ENSG00000178623 G protein-coupled receptor 35 2 240605431-240631259 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level Renal cancer:2.59e-5 (unfavourable), Lung cancer:5.86e-4 (unfavourable) Tissue enhanced Tissue enhanced duodenum: 41.4;small intestine: 42.3 colon: 18.4 Cell line enhanced CACO-2: 17.1;CAPAN-2: 45.0;HDLM-2: 16.3;Hep G2: 22.7;HMC-1: 27.8 +C10orf53 Em:AC069546.1 ENSG00000178645 Chromosome 10 open reading frame 53 10 49679651-49710261 Predicted intracellular proteins Evidence at protein level HPA037951 Enhanced Not detected Tissue enriched 60 testis: 43.5 fallopian tube: 0.7 Not detected +CSRNP3 FAM130A2, FLJ32093, PPP1R73, TAIP-2 ENSG00000178662 Cysteine and serine rich nuclear protein 3 2 165469647-165689407 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA017905 Supported Approved Nucleus
Nucleoli Mixed Tissue enhanced cerebral cortex: 16.1 endometrium: 4.6 Group enriched 5 AF22: 9.7;PC-3: 2.2;SCLC-21H: 8.4;SH-SY5Y: 6.2 +ZNF713 FLJ39963 ENSG00000178665 Zinc finger protein 713 7 55887475-55942225 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059425, HPA062887 Uncertain Approved Nucleoli Mixed Mixed testis: 8.4 Cell line enhanced SH-SY5Y: 7.3 +PARP10 FLJ14464 ENSG00000178685 Poly(ADP-ribose) polymerase family member 10 8 143977153-144012772 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028122, HPA052427 Approved Supported Nucleoli
Cytosol Expressed in all Expressed in all spleen: 56.4 Mixed +DYNAP C18orf26, FLJ39106 ENSG00000178690 Dynactin associated protein 18 54587757-54599493 Predicted membrane proteins Evidence at protein level HPA011148 Uncertain Tissue enhanced Tissue enriched 7 esophagus: 32.1 spleen: 4.3 Cell line enhanced Karpas-707: 8.9 +SUZ12 CHET9, JJAZ1, KIAA0160 ENSG00000178691 SUZ12 polycomb repressive complex 2 subunit 17 31937018-32001045 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA057436 Approved Approved Nucleus
Nucleoli
Nuclear bodies Expressed in all Expressed in all testis: 50.7 Expressed in all +NSUN3 FLJ22609 ENSG00000178694 NOP2/Sun RNA methyltransferase family member 3 3 94062916-94128545 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036181, HPA057979 Uncertain Approved Nucleoplasm
Nuclear membrane Expressed in all Mixed testis: 8.0 Expressed in all +KCTD12 C13orf2, KIAA1778, PFET1 ENSG00000178695 Potassium channel tetramerization domain containing 12 13 76880166-76886390 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056987, HPA077376 Supported Approved Mitochondria Renal cancer:1.14e-4 (favourable) Expressed in all Expressed in all fallopian tube: 122.8 Cell line enhanced HUVEC TERT2: 191.1;TIME: 151.4 +DHFR2 DHFRL1, DHFRP4, FLJ16119 ENSG00000178700 Dihydrofolate reductase 2 3 94047836-94063389 Enzymes, Predicted intracellular proteins Evidence at protein level HPA051465 Uncertain Supported Mitochondria Renal cancer:2.30e-6 (favourable) Expressed in all Mixed parathyroid gland: 16.2 Mixed +RPP25 FLJ20374 ENSG00000178718 Ribonuclease P and MRP subunit p25 15 74954416-74957464 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046900 Approved Supported Nucleoplasm
Microtubule organizing center Glioma:3.67e-5 (unfavourable) Expressed in all Mixed ovary: 12.2 Cell line enhanced SCLC-21H: 38.4;SK-MEL-30: 39.1 +GRINA HNRGW, LFG1, NMDARA1, TMBIM3 ENSG00000178719 Glutamate ionotropic receptor NMDA type subunit associated protein 1 8 143990058-143993415 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA036980, HPA036981 Approved Approved Nucleoli fibrillar center
Cytosol Expressed in all Expressed in all seminal vesicle: 264.5 Expressed in all +THBD CD141 ENSG00000178726 Thrombomodulin 20 23045633-23049741 Candidate cardiovascular disease genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level CAB002425, HPA002982 Supported Approved Nucleoplasm
Cytosol Expressed in all Expressed in all lung: 73.3 Cell line enhanced CAPAN-2: 33.8;EFO-21: 30.9;HaCaT: 28.6;hTCEpi: 30.3 +GP5 CD42d ENSG00000178732 Glycoprotein V platelet 3 194394821-194398354 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enhanced lymph node: 1.3 fallopian tube: 1.1 Cell line enriched 10 HEL: 14.6 +LMO7DN C13orf45 ENSG00000178734 LMO7 downstream neighbor 13 75871038-75883811 Predicted intracellular proteins Evidence at transcript level HPA052013 Uncertain Not detected Tissue enhanced gallbladder: 1.3 esophagus,lung,testis: 0.7 Cell line enhanced LHCN-M2: 1.1 +COX5A ENSG00000178741 Cytochrome c oxidase subunit 5A 15 74919791-74938168 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA027526 Supported Renal cancer:6.06e-7 (favourable), Cervical cancer:2.15e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 548.4 Expressed in all +STX19 MGC21382 ENSG00000178750 Syntaxin 19 3 94014369-94028610 Predicted intracellular proteins Evidence at protein level HPA030604 Uncertain Approved Intermediate filaments
Cytosol Mixed Tissue enhanced epididymis: 19.7 rectum: 14.5 Cell line enhanced CAPAN-2: 5.2;HaCaT: 1.1;hTCEpi: 2.9 +ERFE C1QTNF15, CTRP15, FAM132B, FLJ37034 ENSG00000178752 Erythroferrone 2 238158982-238168900 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA077259 Approved Endoplasmic reticulum
Microtubule organizing center Renal cancer:2.46e-4 (unfavourable), Endometrial cancer:3.75e-4 (unfavourable) Tissue enhanced Group enriched 8 testis: 17.2;thyroid gland: 40.6 appendix: 3.4 Cell line enhanced RH-30: 25.5 +FAM219B C15orf17, FLJ00005 ENSG00000178761 Family with sequence similarity 219 member B 15 74899987-74907121 Predicted intracellular proteins Evidence at protein level HPA048929, HPA058064 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:1.29e-4 (favourable), Colorectal cancer:1.75e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 20.8 Mixed +ZHX2 KIAA0854 ENSG00000178764 Zinc fingers and homeoboxes 2 8 122781394-122974512 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006769, HPA006996 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all ovary: 32.8 Cell line enhanced REH: 47.1 +CPN2 ACBP ENSG00000178772 Carboxypeptidase N subunit 2 3 194339765-194351328 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA004732 Uncertain Liver cancer:2.05e-4 (favourable), Renal cancer:4.59e-4 (unfavourable) Tissue enriched Tissue enriched 7 liver: 113.6 kidney: 15.6 Cell line enriched 17 Hep G2: 41.9 +CPNE7 ENSG00000178773 Copine 7 16 89575768-89597246 Predicted intracellular proteins Evidence at protein level HPA043359 Uncertain Renal cancer:9.52e-6 (unfavourable), Urothelial cancer:7.22e-4 (favourable) Mixed Tissue enhanced epididymis: 23.6 cerebral cortex: 9.8 Cell line enhanced HHSteC: 87.2 +C5orf46 MGC23985, SSSP1 ENSG00000178776 Chromosome 5 open reading frame 46 5 147880726-147906538 Predicted secreted proteins Evidence at transcript level HPA058999 Approved Nuclear speckles
Mitochondria Renal cancer:1.75e-9 (unfavourable), Cervical cancer:3.98e-4 (unfavourable) Tissue enhanced Group enriched 8 breast: 17.6;salivary gland: 77.2;skin: 62.4;testis: 19.9 heart muscle: 5.8 Cell line enhanced PC-3: 83.2;SiHa: 21.5;U-2 OS: 59.9;U-251 MG: 19.3 +CD300LB CLM7, TREM5 ENSG00000178789 CD300 molecule like family member b 17 74521174-74531474 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced appendix: 11.4 spleen: 5.2 Cell line enhanced HL-60: 1.5;NB-4: 1.5;THP-1: 1.3 +GDPD4 GDE6 ENSG00000178795 Glycerophosphodiester phosphodiesterase domain containing 4 11 77216558-77301687 Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enriched 12 testis: 4.7 placenta: 0.3 Not detected +RIIAD1 C1orf230, FLJ36032, NCRNA00166 ENSG00000178796 Regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 1 151710433-151729805 Predicted intracellular proteins Evidence at protein level HPA045703 Enhanced Approved Nucleoplasm
Cytosol Endometrial cancer:5.46e-4 (favourable) Tissue enhanced Group enriched 9 fallopian tube: 70.7;testis: 22.5 cerebral cortex: 5.4 Group enriched 9 CACO-2: 3.6;SCLC-21H: 2.7;SH-SY5Y: 4.8;SK-BR-3: 5.4 +MPI ENSG00000178802 Mannose phosphate isomerase 15 74890005-74902219 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007200 Approved Approved Plasma membrane
Cytosol Head and neck cancer:2.39e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 52.3 Expressed in all +H1FOO ENSG00000178804 H1 histone family member O, oocyte specific 3 129543214-129551467 Predicted intracellular proteins Evidence at protein level HPA037992 Enhanced Not detected Tissue enriched 59 testis: 5.8 all non-specific tissues: 0.0 Not detected +TRIM73 TRIM50B ENSG00000178809 Tripartite motif containing 73 7 75395063-75410996 Predicted intracellular proteins Evidence at transcript level HPA047843, HPA051845 Uncertain Approved Cytosol Not detected Mixed stomach: 8.8 Cell line enhanced Hep G2: 7.1 +OPLAH 5-Opase, OPLA ENSG00000178814 5-oxoprolinase (ATP-hydrolysing) 8 144051266-144063965 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026562, HPA028260, HPA052429 Uncertain Approved Nucleoli fibrillar center Renal cancer:1.53e-6 (favourable) Expressed in all Tissue enhanced testis: 58.2 duodenum: 13.8 Cell line enhanced AN3-CA: 31.2;BEWO: 20.2;PC-3: 24.2 +TMEM52 ENSG00000178821 Transmembrane protein 52 1 1917590-1919273 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced pancreas: 38.8;skeletal muscle: 105.7 adrenal gland: 24.4 Cell line enhanced Hep G2: 13.9;RPMI-8226: 25.7 +TMEM139 FLJ90586 ENSG00000178826 Transmembrane protein 139 7 143279957-143288048 Predicted membrane proteins, Transporters Evidence at protein level HPA036982, HPA036983 Approved Approved Plasma membrane
Focal adhesion sites Renal cancer:3.05e-5 (favourable), Pancreatic cancer:1.66e-4 (unfavourable) Mixed Tissue enhanced duodenum: 34.0;kidney: 34.6 small intestine: 20.7 Cell line enhanced CAPAN-2: 35.7;EFO-21: 26.3;RPTEC TERT1: 53.2;T-47d: 64.1 +RNF186 FLJ20225 ENSG00000178828 Ring finger protein 186 1 19814029-19815278 Predicted membrane proteins Evidence at protein level HPA034547, HPA035558 Enhanced Tissue enhanced Tissue enhanced duodenum: 132.4;epididymis: 82.2;small intestine: 46.5 kidney: 26.2 Cell line enhanced RPMI-8226: 1.2 +EFCAB13 C17orf57, FLJ40342 ENSG00000178852 EF-hand calcium binding domain 13 17 47323290-47441312 Predicted intracellular proteins Evidence at protein level CAB002501, HPA021633, HPA023249, HPA026561 Uncertain Supported Nucleus
Nuclear speckles
Cytosol Mixed Tissue enhanced testis: 37.3 thyroid gland: 23.6 Mixed +MSC ABF-1, bHLHa22 ENSG00000178860 Musculin 8 71841549-71844468 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062878 Supported Nucleoplasm Renal cancer:1.07e-13 (unfavourable), Liver cancer:4.83e-5 (unfavourable), Glioma:7.15e-4 (unfavourable) Expressed in all Mixed placenta: 22.4 Cell line enriched 14 HDLM-2: 729.2 +APOLD1 DKFZP434F0318, FLJ25138 ENSG00000178878 Apolipoprotein L domain containing 1 12 12725917-12829975 Predicted membrane proteins Evidence at protein level HPA052462, HPA058882 Approved Enhanced Nucleoplasm
Cytosol Expressed in all Tissue enhanced adipose tissue: 142.9 placenta: 123.3 Cell line enhanced AF22: 35.9;HDLM-2: 17.8 +RFLNA Cfm2, FAM101A, FLJ44614, RefilinA ENSG00000178882 Refilin A 12 123973241-124316024 Predicted intracellular proteins Evidence at protein level HPA058911, HPA078021 Enhanced Approved Nucleoplasm
Golgi apparatus Lung cancer:3.16e-5 (unfavourable) Mixed Tissue enriched 5 stomach: 90.8 small intestine: 16.8 Cell line enhanced hTEC/SVTERT24-B: 13.8;HUVEC TERT2: 16.5;LHCN-M2: 28.9;RH-30: 10.8 +EXOSC4 FLJ20591, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p ENSG00000178896 Exosome component 4 8 144078626-144080647 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024792 Approved Supported Intermediate filaments
Cytosol Ovarian cancer:2.23e-4 (favourable) Expressed in all Expressed in all testis: 56.1 Expressed in all +DPY19L3 ENSG00000178904 Dpy-19 like 3 (C. elegans) 19 32405543-32485895 Predicted membrane proteins Evidence at protein level HPA008325 Approved Approved Microtubules Pancreatic cancer:1.70e-4 (favourable), Head and neck cancer:5.55e-4 (favourable) Expressed in all Mixed cerebral cortex: 20.3 Expressed in all +TAF7 TAF2F, TAFII55 ENSG00000178913 TATA-box binding protein associated factor 7 5 141260225-141320821 Predicted intracellular proteins Evidence at protein level HPA006429 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all testis: 138.7 Expressed in all +ZNF852 ENSG00000178917 Zinc finger protein 852 3 44498970-44510636 Predicted intracellular proteins Evidence at protein level HPA048312, HPA049885, HPA071850 Uncertain Mixed Mixed parathyroid gland: 2.8 Mixed +FOXE1 FKHL15, FOXE2, HFKH4, TITF2, TTF-2 ENSG00000178919 Forkhead box E1 9 97853254-97856715 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enhanced Tissue enriched 15 thyroid gland: 327.9 tonsil: 22.1 Cell line enhanced A-431: 12.2;HeLa: 13.5;RPTEC TERT1: 14.9;SiHa: 15.7 +PFAS FGARAT, KIAA0361, PURL ENSG00000178921 Phosphoribosylformylglycinamidine synthase 17 8247618-8270491 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022140, HPA022886 Enhanced Approved Nucleoplasm
Plasma membrane Liver cancer:9.19e-4 (unfavourable) Expressed in all Expressed in all lymph node: 11.6 Expressed in all +HYI HT036 ENSG00000178922 Hydroxypyruvate isomerase (putative) 1 43451003-43453989 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040092 Uncertain Approved Golgi apparatus
Plasma membrane
Cytosol Urothelial cancer:2.72e-5 (favourable), Renal cancer:2.75e-5 (unfavourable), Colorectal cancer:4.96e-4 (unfavourable), Liver cancer:5.55e-4 (unfavourable), Breast cancer:9.18e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 81.4 Mixed +C17orf62 FLJ90469, MGC4368 ENSG00000178927 Chromosome 17 open reading frame 62 17 82442589-82450829 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045696 Uncertain Approved Plasma membrane
Cell Junctions Renal cancer:6.83e-11 (unfavourable) Expressed in all Expressed in all lymph node: 127.0 Expressed in all +TPRX1 FLJ40321 ENSG00000178928 Tetrapeptide repeat homeobox 1 19 47801243-47819051 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA044922 Uncertain Not detected Tissue enriched 13 testis: 1.3 endometrium: 0.1 Not detected +LGALS7B GAL7 ENSG00000178934 Galectin 7B 19 38789211-38791749 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001549, CAB025100 Supported Endometrial cancer:1.59e-4 (unfavourable) Group enriched Tissue enhanced breast: 10.4;esophagus: 19.3 skeletal muscle: 3.8 Cell line enriched 21 HaCaT: 3.7 +ZNF552 FLJ21603 ENSG00000178935 Zinc finger protein 552 19 57803841-57814913 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043800, HPA053762, HPA072145 Uncertain Uncertain Nucleus Colorectal cancer:2.66e-4 (favourable), Breast cancer:4.57e-4 (favourable), Head and neck cancer:9.96e-4 (favourable) Expressed in all Mixed breast: 33.9 Expressed in all +SMIM10L2A LED, LINC00086, MGC39606, NCRNA00086 ENSG00000178947 Small integral membrane protein 10 like 2A X 135421943-135428074 Predicted membrane proteins Evidence at transcript level Renal cancer:8.28e-8 (favourable), Endometrial cancer:6.78e-4 (unfavourable) Tissue enhanced Tissue enhanced adrenal gland: 21.8;cerebral cortex: 22.5 epididymis: 17.6 Cell line enhanced AN3-CA: 4.8;HAP1: 10.7;hTCEpi: 3.9 +GAK DNAJC26 ENSG00000178950 Cyclin G associated kinase 4 849276-932373 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027405, HPA027459, HPA027463 Approved Enhanced Golgi apparatus
Vesicles Renal cancer:1.70e-6 (favourable), Urothelial cancer:7.41e-4 (favourable) Expressed in all Expressed in all duodenum: 51.5 Expressed in all +ZBTB7A DKFZp547O146, FBI-1, LRF, pokemon, ZBTB7, ZNF857A ENSG00000178951 Zinc finger and BTB domain containing 7A 19 4044364-4066945 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB037214, CAB037285, HPA046387 Enhanced Approved Nucleoplasm Renal cancer:1.34e-6 (favourable), Endometrial cancer:6.50e-6 (favourable), Stomach cancer:1.79e-4 (favourable), Pancreatic cancer:2.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 23.9 Expressed in all +TUFM EF-TuMT, EFTu ENSG00000178952 Tu translation elongation factor, mitochondrial 16 28842411-28846408 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018991, HPA024087, CAB075730, CAB075731 Enhanced Enhanced Mitochondria Renal cancer:2.69e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 162.7 Expressed in all +ERICH3 C1orf173, DKFZp547I048, RP11-653A5.1 ENSG00000178965 Glutamate rich 3 1 74568111-74673738 Predicted intracellular proteins Evidence at protein level HPA028655 Approved Endometrial cancer:1.56e-5 (favourable) Tissue enhanced Group enriched 6 cerebral cortex: 18.9;cervix, uterine: 8.6;fallopian tube: 27.7;testis: 43.1 lung: 4.2 Not detected +RMI1 BLAP75, C9orf76, FLJ12888 ENSG00000178966 RecQ mediated genome instability 1 9 83980711-84004074 Predicted intracellular proteins Evidence at protein level HPA021661 Supported Nucleoplasm
Nuclear bodies Liver cancer:8.71e-4 (unfavourable) Expressed in all Expressed in all testis: 21.0 Expressed in all +CTC1 AAF132, C17orf68, FLJ22170 ENSG00000178971 CST telomere replication complex component 1 17 8224821-8248044 Disease related genes, Predicted intracellular proteins Evidence at protein level Pancreatic cancer:6.49e-5 (favourable) Expressed in all Expressed in all spleen: 30.9 Expressed in all +FBXO34 Fbx34, FLJ20725 ENSG00000178974 F-box protein 34 14 55271303-55361918 Predicted intracellular proteins Evidence at protein level HPA052592 Uncertain Approved Nuclear speckles Renal cancer:1.20e-13 (favourable) Expressed in all Expressed in all testis: 47.1 Expressed in all +SELENOW SELW, SEPW1 ENSG00000178980 Selenoprotein W 19 47778572-47784686 Predicted intracellular proteins Evidence at protein level Lung cancer:5.44e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 440.9 Mixed +EIF3K ARG134, eIF3k, EIF3S12, HSPC029, M9, PLAC-24, PRO1474, PTD001 ENSG00000178982 Eukaryotic translation initiation factor 3 subunit K 19 38619082-38636955 Predicted intracellular proteins Evidence at protein level HPA045446, HPA054590 Uncertain Supported Cytosol Cervical cancer:1.31e-4 (favourable), Renal cancer:5.43e-4 (favourable) Expressed in all Expressed in all fallopian tube: 164.9 Expressed in all +MRFAP1L1 MGC9651 ENSG00000178988 Morf4 family associated protein 1 like 1 4 6707701-6709880 Predicted intracellular proteins Evidence at protein level Renal cancer:2.80e-5 (favourable), Urothelial cancer:5.26e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 91.2 Expressed in all +SNX18 SH3PX2, SH3PXD3B, SNAG1 ENSG00000178996 Sorting nexin 18 5 54517759-54546585 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037800 Approved Approved Cytosol Renal cancer:1.58e-4 (favourable) Expressed in all Expressed in all bone marrow: 43.8 Mixed +EXD1 EXDL1, MGC33637 ENSG00000178997 Exonuclease 3'-5' domain containing 1 15 41182725-41230743 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 72 testis: 29.5 epididymis: 0.4 Not detected +AURKB Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5 ENSG00000178999 Aurora kinase B 17 8204733-8210600 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005862, HPA037708 Enhanced Enhanced Nucleoplasm
Midbody Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.24e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 44.4 tonsil: 33.8 Mixed +TAS1R2 GPR71, T1R2, TR2 ENSG00000179002 Taste 1 receptor member 2 1 18839599-18859682 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +C14orf39 SIX6OS1 ENSG00000179008 Chromosome 14 open reading frame 39 14 60396469-60515543 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059518 Uncertain Approved Nucleus
Nucleoli Mixed Tissue enriched 8 testis: 19.7 adrenal gland: 2.4 Cell line enhanced HEL: 5.6;MOLT-4: 19.1;RH-30: 6.0;U-2 OS: 13.1 +MRFAP1 PAM14, PGR1 ENSG00000179010 Morf4 family associated protein 1 4 6640091-6642745 Predicted intracellular proteins Evidence at protein level CAB042447, HPA056367 Approved Approved Nucleus Renal cancer:2.90e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 505.0 Expressed in all +C3orf38 MGC26717 ENSG00000179021 Chromosome 3 open reading frame 38 3 88149743-88168729 Predicted intracellular proteins Evidence at protein level HPA034736, HPA034737 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Ovarian cancer:3.55e-4 (favourable), Prostate cancer:4.12e-4 (unfavourable) Expressed in all Expressed in all testis: 59.0 Expressed in all +KLHDC7A FLJ38753 ENSG00000179023 Kelch domain containing 7A 1 18480982-18486126 Predicted intracellular proteins Evidence at protein level HPA056616 Uncertain Approved Nuclear speckles Renal cancer:7.81e-9 (favourable), Urothelial cancer:1.88e-4 (favourable) Tissue enhanced Tissue enhanced kidney: 20.8 urinary bladder: 6.4 Cell line enhanced A549: 4.7;CAPAN-2: 8.9;EFO-21: 4.8;NTERA-2: 5.6;RPTEC TERT1: 8.6;RT4: 7.4;T-47d: 9.5 +TMEM107 MGC10744 ENSG00000179029 Transmembrane protein 107 17 8173237-8176399 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA052555, HPA059653 Approved Approved Nucleoplasm
Midbody
Midbody ring
Cytosol Endometrial cancer:9.39e-5 (favourable) Expressed in all Mixed fallopian tube: 72.1 Expressed in all +RRS1 KIAA0112 ENSG00000179041 Ribosome biogenesis regulator homolog 8 66429028-66430733 Predicted intracellular proteins Evidence at protein level HPA055549, HPA060937 Approved Enhanced Nucleoli Expressed in all Expressed in all appendix: 16.3 Expressed in all +EXOC3L1 EXOC3L, FLJ35539, FLJ35587 ENSG00000179044 Exocyst complex component 3 like 1 16 67184366-67190204 Predicted intracellular proteins Evidence at transcript level HPA029574 Uncertain Approved Vesicles
Plasma membrane Expressed in all Tissue enhanced spleen: 30.0 placenta: 8.4 Cell line enhanced HUVEC TERT2: 2.8;SCLC-21H: 7.6 +TRIML2 FLJ25801, SPRYD6 ENSG00000179046 Tripartite motif family like 2 4 188091273-188109603 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043838 Uncertain Approved Plasma membrane
Cytosol Tissue enriched Group enriched 26 placenta: 5.9;testis: 3.4 cerebral cortex,lung: 0.1 Cell line enhanced A549: 30.5;BEWO: 17.7;hTCEpi: 15.4;NTERA-2: 34.0 +RCC2 TD-60 ENSG00000179051 Regulator of chromosome condensation 2 1 17406760-17439724 Predicted intracellular proteins Evidence at protein level HPA072281 Approved Liver cancer:3.42e-8 (unfavourable), Renal cancer:4.03e-8 (unfavourable), Melanoma:1.30e-4 (unfavourable), Cervical cancer:3.31e-4 (favourable) Expressed in all Mixed skin: 35.3 Expressed in all +OR13D1 ENSG00000179055 Olfactory receptor family 13 subfamily D member 1 9 104694422-104695462 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA055921 Uncertain Not detected Not detected testis: 0.4 Not detected +IGSF22 FLJ37794, IGFN2 ENSG00000179057 Immunoglobulin superfamily member 22 11 18704305-18726230 Predicted intracellular proteins Evidence at protein level CAB026459 Uncertain Mixed Tissue enhanced skin: 1.2;testis: 1.0 cerebral cortex: 0.8 Not detected +C9orf50 FLJ35803 ENSG00000179058 Chromosome 9 open reading frame 50 9 129612225-129620776 Predicted intracellular proteins Evidence at protein level HPA026743 Enhanced Mixed Tissue enhanced testis: 8.1 cerebral cortex: 1.8 Cell line enhanced MCF7: 1.0 +ZFP42 REX1, ZNF754 ENSG00000179059 ZFP42 zinc finger protein 4 187995771-188005050 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB025557 Uncertain Tissue enriched Tissue enhanced testis: 3.1 placenta: 1.0 Cell line enriched 17 BEWO: 113.6 +CCDC89 FLJ38159 ENSG00000179071 Coiled-coil domain containing 89 11 85684866-85686277 Predicted intracellular proteins Evidence at protein level HPA040628 Enhanced Approved Nucleoplasm Mixed Tissue enhanced fallopian tube: 19.3;testis: 53.4 ovary: 8.1 Cell line enhanced SCLC-21H: 6.3;U-2197: 5.7 +FAM133A CT115, FLJ37659, RP1-32F7.2 ENSG00000179083 Family with sequence similarity 133 member A X 93674013-93712274 Predicted intracellular proteins Evidence at protein level HPA066175, HPA069513 Approved Nucleus
Nucleoli Mixed Group enriched 6 cerebral cortex: 5.3;testis: 14.1 adrenal gland: 1.5 Cell line enhanced Karpas-707: 33.0;U-2197: 22.2;U-266/70: 27.2;U-266/84: 58.1 +DPM3 MGC125904, MGC125905, MGC34275 ENSG00000179085 Dolichyl-phosphate mannosyltransferase subunit 3 1 155139891-155140595 Disease related genes, Predicted membrane proteins Evidence at protein level HPA014667 Approved Endometrial cancer:7.09e-5 (favourable), Ovarian cancer:8.97e-5 (favourable), Urothelial cancer:8.64e-4 (favourable) Expressed in all Expressed in all adrenal gland: 78.5 Expressed in all +C12orf42 FLJ25323 ENSG00000179088 Chromosome 12 open reading frame 42 12 103237591-103496010 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 17 testis: 25.1 spleen: 1.5 Not detected +CYC1 UQCR4 ENSG00000179091 Cytochrome c1 8 144095027-144097525 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA001247 Supported Supported Mitochondria Renal cancer:5.89e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 242.3 Expressed in all +PER1 PER, RIGUI ENSG00000179094 Period circadian clock 1 17 8140472-8156506 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA047947, HPA067064 Supported Nucleoplasm
Cytosol Stomach cancer:1.94e-4 (unfavourable), Liver cancer:2.56e-4 (favourable), Cervical cancer:3.89e-4 (favourable) Expressed in all Expressed in all thyroid gland: 70.3 Expressed in all +HTR1F 5-HT1F, HTR1EL ENSG00000179097 5-hydroxytryptamine receptor 1F 3 87990696-87993835 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA005555 Uncertain Not detected Tissue enhanced placenta: 2.7 cerebral cortex: 1.0 Cell line enhanced K-562: 1.1;LHCN-M2: 1.0 +TMTC2 DKFZp762A217 ENSG00000179104 Transmembrane and tetratricopeptide repeat containing 2 12 82686880-83134870 Predicted membrane proteins Evidence at protein level HPA026954, HPA026955 Uncertain Approved Plasma membrane
Actin filaments Renal cancer:2.84e-5 (favourable) Mixed Mixed cerebral cortex: 16.4 Cell line enhanced AF22: 31.2;WM-115: 76.7 +HES7 bHLHb37 ENSG00000179111 Hes family bHLH transcription factor 7 17 8120590-8124092 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA072105 Uncertain Approved Nucleoplasm Not detected Tissue enhanced placenta: 1.1 testis: 0.9 Cell line enhanced HAP1: 8.4;HDLM-2: 6.2;HeLa: 8.1 +FARSA CML33, FARSL, FARSLA ENSG00000179115 Phenylalanyl-tRNA synthetase alpha subunit 19 12922479-12934037 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001911 Approved Supported Cytosol Cervical cancer:8.23e-4 (favourable), Stomach cancer:8.32e-4 (favourable), Endometrial cancer:9.22e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 67.2 Expressed in all +SPTY2D1 DKFZp686I068, FLJ39441, Spt2 ENSG00000179119 SPT2 chromatin protein domain containing 1 11 18606401-18634791 Predicted intracellular proteins Evidence at protein level HPA039372, HPA047957 Approved Approved Nucleus
Nucleoli Renal cancer:2.07e-4 (favourable), Pancreatic cancer:2.59e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 21.3 Expressed in all +C10orf67 bA215C7.4, C10orf115, LINC01552, MGC46732 ENSG00000179133 Chromosome 10 open reading frame 67 10 23201916-23344845 Predicted intracellular proteins Evidence at transcript level HPA038130, HPA038131 Approved Approved Nucleoplasm
Nucleoli
Nuclear speckles Not detected Tissue enhanced fallopian tube: 7.5;testis: 17.4 lung: 4.0 Cell line enhanced HaCaT: 2.1;SiHa: 4.2 +SAMD4B FLJ10211, hSmaug2, MGC99832, SMGB ENSG00000179134 Sterile alpha motif domain containing 4B 19 39342396-39385710 Predicted intracellular proteins Evidence at protein level HPA016800, HPA059385 Approved Enhanced Cytosol Endometrial cancer:2.17e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 68.4 Expressed in all +CYP11B2 ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo ENSG00000179142 Cytochrome P450 family 11 subfamily B member 2 8 142910559-142917843 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA049171, HPA056348, HPA057752 Supported Not detected Tissue enriched 1057 adrenal gland: 126.3 testis: 0.1 Not detected +GIMAP7 IAN7, MGC27027 ENSG00000179144 GTPase, IMAP family member 7 7 150514830-150521073 Predicted intracellular proteins Evidence at protein level HPA020266, HPA020268 Enhanced Approved Vesicles
Cytosol Liver cancer:8.98e-5 (favourable), Head and neck cancer:7.43e-4 (favourable) Expressed in all Expressed in all lymph node: 181.4 Group enriched 12 HUVEC TERT2: 74.2;MOLT-4: 60.4 +ALOXE3 E-LOX, eLOX3 ENSG00000179148 Arachidonate lipoxygenase 3 17 8095900-8119047 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA023120, HPA078597 Enhanced Approved Plasma membrane
Cytosol Tissue enhanced Tissue enriched 16 skin: 36.5 breast: 2.2 Cell line enhanced A-431: 5.5;HBEC3-KT: 7.2;hTCEpi: 5.2;hTERT-HME1: 10.5;T-47d: 4.1 +EDC3 FLJ21128, hYjeF_N2-15q23, LSM16, YJDC, YJEFN2 ENSG00000179151 Enhancer of mRNA decapping 3 15 74630558-74696292 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040650, HPA044206, HPA066137 Uncertain Supported Cytoplasmic bodies Liver cancer:7.80e-5 (unfavourable) Expressed in all Expressed in all testis: 65.4 Expressed in all +TCAIM C3orf23, DKFZp313N0621, TOAG-1 ENSG00000179152 T-cell activation inhibitor, mitochondrial 3 44338119-44409451 Predicted intracellular proteins Evidence at transcript level Renal cancer:2.19e-7 (favourable), Urothelial cancer:2.81e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 23.1 Expressed in all +FUCA1 ENSG00000179163 Fucosidase, alpha-L- 1, tissue 1 23845077-23868294 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA046542, HPA056371 Enhanced Renal cancer:5.70e-13 (favourable), Endometrial cancer:2.45e-4 (favourable) Expressed in all Expressed in all lymph node: 185.6 Cell line enhanced CAPAN-2: 144.5 +PXT1 STEPP ENSG00000179165 Peroxisomal, testis specific 1 6 36390551-36442889 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 7 testis: 3.5 appendix: 0.4 Cell line enhanced HDLM-2: 2.0 +GGN FLJ35713, MGC33369 ENSG00000179168 Gametogenetin 19 38384265-38388082 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 11 testis: 34.9 small intestine: 3.1 Cell line enhanced BEWO: 2.5 +HNRNPCL1 HNRPCL1 ENSG00000179172 Heterogeneous nuclear ribonucleoprotein C-like 1 1 12847408-12848725 Predicted intracellular proteins Evidence at protein level Not detected Not detected testis: 0.1 Not detected +TMEM125 MGC17299 ENSG00000179178 Transmembrane protein 125 1 43269994-43274002 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA015796 Approved Midbody
Cytosol Renal cancer:2.91e-9 (favourable), Lung cancer:5.11e-5 (favourable) Mixed Tissue enhanced lung: 113.7 thyroid gland: 51.5 Cell line enhanced A-431: 23.4;BEWO: 21.1;CAPAN-2: 42.6;SK-BR-3: 31.0;T-47d: 31.2 +ZNF664 DKFZp761B128, ZFOC1, ZNF176 ENSG00000179195 Zinc finger protein 664 12 123971845-124015439 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA047846 Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 236.1 Expressed in all +SIGLECL1 C19orf75, FLJ40235, SIGLEC23P, SIGLECP7 ENSG00000179213 SIGLEC family like 1 19 51246348-51269330 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 86 testis: 40.1 cervix, uterine: 0.4 Not detected +CALR cC1qR, CRT, FLJ26680, RO, SSA ENSG00000179218 Calreticulin 19 12938578-12944489 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB001513, HPA002242, CAB019952 Enhanced Renal cancer:1.11e-16 (unfavourable), Ovarian cancer:1.10e-4 (favourable) Expressed in all Expressed in all thyroid gland: 1652.0 Expressed in all +MAGED1 DLXIN-1, NRAGE ENSG00000179222 MAGE family member D1 X 51803007-51902357 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA043645 Approved Cytosol Thyroid cancer:3.25e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 193.9 Mixed +RP11-111M22.2 ENSG00000179240 11 76381313-76414619 Predicted intracellular proteins Evidence at transcript level HPA057405 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Centrosome Not detected Mixed testis: 8.4 Mixed +LDLRAD3 LRAD3 ENSG00000179241 Low density lipoprotein receptor class A domain containing 3 11 35943981-36232136 Predicted membrane proteins Evidence at protein level HPA038251 Approved Supported Cell Junctions Renal cancer:5.05e-8 (unfavourable), Lung cancer:9.34e-6 (unfavourable), Urothelial cancer:2.14e-5 (unfavourable), Cervical cancer:2.24e-4 (unfavourable) Expressed in all Mixed breast: 23.0 Mixed +CDH4 ENSG00000179242 Cadherin 4 20 61252426-61940617 Predicted membrane proteins Evidence at protein level HPA015613 Enhanced Plasma membrane Group enriched Tissue enhanced cerebral cortex: 6.0;spleen: 4.8 seminal vesicle: 1.3 Cell line enhanced AF22: 11.0;hTERT-HME1: 11.2;U-2 OS: 20.6;U-251 MG: 29.8 +SMCO3 C12orf69, LOC440087 ENSG00000179256 Single-pass membrane protein with coiled-coil domains 3 12 14804650-14814182 Predicted membrane proteins Evidence at protein level HPA040574, HPA047804 Uncertain Tissue enhanced Tissue enhanced cervix, uterine: 5.6 gallbladder,kidney: 3.0 Cell line enhanced AN3-CA: 1.8 +RAD23A HHR23A, MGC111083 ENSG00000179262 RAD23 homolog A, nucleotide excision repair protein 19 12945855-12953642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA026418, HPA053901, HPA057003, HPA065599 Supported Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all skeletal muscle: 334.1 Expressed in all +C2orf71 FLJ34931, RP54 ENSG00000179270 Chromosome 2 open reading frame 71 2 29060976-29074261 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051819 Uncertain Not detected Not detected heart muscle,ovary: 0.3 Not detected +GADD45GIP1 CKBBP2, CKbetaBP2, CRIF1, MGC4667, MGC4758, PLINP-1, Plinp1, PRG6 ENSG00000179271 GADD45G interacting protein 1 19 12953119-12957236 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055205, HPA065048 Supported Supported Mitochondria Expressed in all Expressed in all cerebral cortex: 29.7 Expressed in all +DAND5 CER2, CKTSF1B3, Coco, DANTE, DTE, FLJ38607, GREM3 ENSG00000179284 DAN domain BMP antagonist family member 5 19 12965159-12974762 Predicted secreted proteins Evidence at transcript level HPA043493, HPA049472 Uncertain Approved Mitochondria Mixed Tissue enhanced heart muscle: 5.2 bone marrow,cerebral cortex: 1.3 Cell line enriched 16 SH-SY5Y: 19.9 +TMEM151A MGC33486, TMEM151 ENSG00000179292 Transmembrane protein 151A 11 66291870-66296664 Predicted membrane proteins Evidence at transcript level HPA041035 Uncertain Approved Nucleoli
Cytosol Tissue enhanced Tissue enriched 24 cerebral cortex: 45.2 adrenal gland: 1.8 Group enriched 7 SCLC-21H: 17.8;SH-SY5Y: 3.7 +PTPN11 BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2 ENSG00000179295 Protein tyrosine phosphatase, non-receptor type 11 12 112418351-112509913 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB005377 Approved Supported Nucleus
Nucleoli
Actin filaments
Cytosol Expressed in all Expressed in all cerebral cortex: 126.0 Expressed in all +NSUN7 FLJ14001 ENSG00000179299 NOP2/Sun RNA methyltransferase family member 7 4 40749897-40809985 Predicted intracellular proteins Evidence at protein level HPA020653 Uncertain Supported Vesicles Renal cancer:2.76e-8 (favourable) Mixed Tissue enhanced testis: 31.5 fallopian tube: 11.4 Cell line enhanced CAPAN-2: 5.0;Karpas-707: 2.9;T-47d: 3.9 +ZCCHC5 FLJ38865, Mar3, Mart3, ZHC5 ENSG00000179300 Zinc finger CCHC-type containing 5 X 78656069-78659328 Predicted intracellular proteins Evidence at transcript level HPA051991, HPA053174, HPA075136 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Not detected Not detected endometrium: 0.8 Cell line enhanced fHDF/TERT166: 1.4;HBF TERT88: 2.3;hTEC/SVTERT24-B: 1.7;RH-30: 2.0;U-251 MG: 1.3 +FAM156B TMEM29B ENSG00000179304 Family with sequence similarity 156 member B X 52891306-52908560 Predicted intracellular proteins Evidence at protein level HPA056640, HPA056643 Uncertain Not detected Tissue enhanced placenta: 46.8 skin: 24.9 Expressed in all +WSCD1 KIAA0523 ENSG00000179314 WSC domain containing 1 17 5772234-6124427 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA015919 Uncertain Approved Nucleoplasm
Golgi apparatus Group enriched Tissue enhanced cerebral cortex: 30.3;spleen: 19.0 testis: 14.9 Cell line enhanced AF22: 39.4;HUVEC TERT2: 20.9;PC-3: 23.1;RH-30: 61.0;SCLC-21H: 18.5 +RAB39A RAB39 ENSG00000179331 RAB39A, member RAS oncogene family 11 107928503-107963482 Predicted intracellular proteins Evidence at protein level HPA042505 Uncertain Mixed Tissue enhanced cerebral cortex: 7.0 spleen: 4.3 Cell line enhanced RPMI-8226: 11.4;SCLC-21H: 33.8;SH-SY5Y: 18.8 +CLK3 clk3 ENSG00000179335 CDC like kinase 3 15 74598500-74645414 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046817 Approved Supported Nucleoplasm
Intermediate filaments Colorectal cancer:2.05e-6 (unfavourable), Prostate cancer:5.92e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 71.7 Expressed in all +HLA-DQB1 CELIAC1, HLA-DQB, IDDM1 ENSG00000179344 Major histocompatibility complex, class II, DQ beta 1 6 32659467-32668383 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013667 Uncertain Supported Golgi apparatus
Rods & Rings Expressed in all Tissue enhanced lymph node: 287.3 lung: 268.5 Cell line enriched 8 HDLM-2: 555.8 +GATA2 NFE1B ENSG00000179348 GATA binding protein 2 3 128479427-128493185 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005633, CAB024847 Approved Supported Nucleoplasm Urothelial cancer:5.22e-5 (favourable), Renal cancer:2.04e-4 (favourable) Expressed in all Tissue enhanced prostate: 62.7;seminal vesicle: 74.7 endometrium: 40.5 Cell line enhanced BEWO: 272.0;HEL: 324.7;HMC-1: 165.0;SH-SY5Y: 347.2 +ARID3B BDP, DRIL2 ENSG00000179361 AT-rich interaction domain 3B 15 74541177-74598131 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050320 Enhanced Supported Nucleoplasm Expressed in all Tissue enhanced testis: 35.9 placenta: 22.3 Cell line enhanced NTERA-2: 86.8 +TMEM31 MGC39655 ENSG00000179363 Transmembrane protein 31 X 103710909-103714028 Predicted membrane proteins Evidence at protein level HPA052760 Approved Nucleoli fibrillar center Tissue enhanced Tissue enriched 64 testis: 85.3 ovary,placenta: 1.3 Cell line enhanced BEWO: 4.1;MCF7: 4.9;NTERA-2: 1.9 +PACS2 KIAA0602, PACS1L ENSG00000179364 Phosphofurin acidic cluster sorting protein 2 14 105300563-105398147 Predicted intracellular proteins, Transporters Evidence at protein level HPA001423, HPA077892 Approved Approved Mitochondria Liver cancer:3.11e-5 (unfavourable), Renal cancer:1.56e-4 (favourable), Pancreatic cancer:2.95e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 63.3 Expressed in all +ELMOD2 MGC10084 ENSG00000179387 ELMO domain containing 2 4 140524158-140553770 Predicted intracellular proteins Evidence at protein level HPA047600 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:1.17e-8 (favourable), Thyroid cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 28.2 Expressed in all +EGR3 PILOT ENSG00000179388 Early growth response 3 8 22687659-22693302 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA006206, CAB009373 Uncertain Uncertain Nucleus
Vesicles Breast cancer:1.83e-4 (favourable), Melanoma:4.78e-4 (favourable) Mixed Mixed gallbladder: 49.6 Cell line enhanced HMC-1: 8.5;MCF7: 25.2;SK-MEL-30: 17.0 +C1orf101 MGC33370 ENSG00000179397 Chromosome 1 open reading frame 101 1 244454377-244641177 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 12 testis: 38.5 epididymis: 3.3 Not detected +GPC5 ENSG00000179399 Glypican 5 13 91398607-92873682 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040152, HPA044081 Enhanced Approved Nucleus
Cytosol Glioma:5.67e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 15.8;kidney: 8.1;testis: 11.5 lung: 4.9 Group enriched 9 CACO-2: 41.2;HeLa: 18.9 +VWA1 FLJ22215, VWA-1, WARP ENSG00000179403 Von Willebrand factor A domain containing 1 1 1434861-1442882 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Expressed in all Tissue enhanced seminal vesicle: 293.3 prostate: 129.1 Cell line enhanced CAPAN-2: 120.1;Hep G2: 57.0;SCLC-21H: 56.1;T-47d: 57.5 +DNAJB8 CT156, MGC33884 ENSG00000179407 DnaJ heat shock protein family (Hsp40) member B8 3 128462439-128467248 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 306 testis: 30.5 all non-specific tissues: 0.0 Not detected +GEMIN4 DKFZP434B131, DKFZP434D174, HC56, HCAP1, HHRF-1, p97 ENSG00000179409 Gem nuclear organelle associated protein 4 17 744414-753999 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065699, HPA067891 Uncertain Supported Nuclear bodies
Cytosol Expressed in all Expressed in all testis: 78.2 Expressed in all +HNRNPCL4 ENSG00000179412 Heterogeneous nuclear ribonucleoprotein C-like 4 1 13164586-13165467 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +FJX1 FLJ22416, FLJ25593 ENSG00000179431 Four jointed box 1 11 35618419-35620868 Predicted secreted proteins Evidence at protein level HPA059220 Uncertain Approved Vesicles Renal cancer:9.24e-9 (unfavourable), Urothelial cancer:6.56e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 22.4 endometrium: 8.8 Mixed +KLHL28 BTBD5, FLJ20081 ENSG00000179454 Kelch like family member 28 14 44924319-45042322 Predicted intracellular proteins Evidence at transcript level HPA000988 Approved Cytosol Expressed in all Mixed bone marrow: 17.2 Expressed in all +MKRN3 D15S9, MGC88288, RNF63, ZFP127, ZNF127 ENSG00000179455 Makorin ring finger protein 3 15 23565678-23630075 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029494 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Glioma:9.23e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 5.9;placenta: 4.1;testis: 3.6 epididymis: 1.1 Cell line enhanced K-562: 22.8 +ZBTB18 C2H2-171, RP58, TAZ-1, ZNF238 ENSG00000179456 Zinc finger and BTB domain containing 18 1 244048939-244057476 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Urothelial cancer:6.78e-6 (favourable), Endometrial cancer:1.34e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 76.3 Mixed +OR9A2 ENSG00000179468 Olfactory receptor family 9 subfamily A member 2 7 143026158-143027195 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +C14orf28 DRIP-1 ENSG00000179476 Chromosome 14 open reading frame 28 14 44897295-44907257 Predicted intracellular proteins Evidence at transcript level HPA059635 Approved Cytosol Expressed in all Mixed testis: 15.6 Mixed +ALOX12B 12R-LOX ENSG00000179477 Arachidonate 12-lipoxygenase, 12R type 17 8072636-8087703 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024002 Supported Approved Cytosol Group enriched Group enriched 7 skin: 70.0;tonsil: 17.2 esophagus: 6.2 Cell line enhanced HEK 293: 1.2;hTCEpi: 1.0 +SLC17A8 DFNA25, VGLUT3 ENSG00000179520 Solute carrier family 17 member 8 12 100357079-100422059 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB079058 Supported Tissue enhanced Tissue enhanced small intestine: 5.8 cerebral cortex: 1.2 Not detected +SHARPIN DKFZP434N1923, SIPL1 ENSG00000179526 SHANK associated RH domain interactor 8 144098633-144108124 Predicted intracellular proteins Evidence at protein level HPA044453 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all testis: 66.1 Expressed in all +LBX2 ENSG00000179528 Ladybird homeobox 2 2 74497517-74503316 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA044257 Uncertain Approved Nucleus
Midbody Mixed Tissue enhanced duodenum: 5.3;small intestine: 5.3 stomach: 3.0 Cell line enhanced Hep G2: 14.9 +DNHD1 C11orf47, CCDC35, DHCD1, DKFZp686J0796, DNHD1L, FLJ32752, FLJ35709, FLJ46184 ENSG00000179532 Dynein heavy chain domain 1 11 6497260-6593758 Predicted intracellular proteins Evidence at protein level HPA039698, HPA040267, HPA057639 Uncertain Approved Nucleoplasm
Cytokinetic bridge Mixed Tissue enriched 6 testis: 19.5 bone marrow: 3.5 Mixed +SLITRK4 DKFZp547M2010 ENSG00000179542 SLIT and NTRK like family member 4 X 143622790-143635777 Predicted membrane proteins Evidence at protein level HPA000431 Enhanced Uncertain Microtubules Tissue enhanced Tissue enhanced adrenal gland: 13.9;cerebral cortex: 12.8 cervix, uterine: 8.4 Cell line enhanced HeLa: 3.9;HHSteC: 2.5;T-47d: 8.3;U-2 OS: 3.5 +HTR1D 5-HT1D, HT1DA, HTRL, RDC4 ENSG00000179546 5-hydroxytryptamine receptor 1D 1 23191895-23194729 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Liver cancer:1.86e-4 (unfavourable), Pancreatic cancer:5.30e-4 (unfavourable) Mixed Group enriched 8 duodenum: 9.4;gallbladder: 2.5;small intestine: 9.1 fallopian tube: 0.9 Cell line enhanced A549: 9.5;SiHa: 7.5;TIME: 21.6;U-2 OS: 9.0 +GCC1 FLJ22035, GCC1P, GCC88, MGC20706 ENSG00000179562 GRIP and coiled-coil domain containing 1 7 127580618-127593611 Predicted intracellular proteins Evidence at protein level HPA019369, HPA021323 Enhanced Enhanced Golgi apparatus
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 18.7 Expressed in all +LSMEM2 C3orf45, FLJ38608 ENSG00000179564 Leucine rich single-pass membrane protein 2 3 50279027-50288114 Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced heart muscle: 15.4;skeletal muscle: 5.4 testis: 2.8 Not detected +RNF151 ENSG00000179580 Ring finger protein 151 16 1966823-1968975 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 430 testis: 73.0 appendix,skin,stomach,thyroid gland: 0.1 Not detected +CIITA C2TA, MHC2TA, NLRA ENSG00000179583 Class II major histocompatibility complex transactivator 16 10866222-10932281 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB016084 Enhanced Approved Nucleoplasm Expressed in all Mixed lymph node,spleen: 59.2 Cell line enhanced HDLM-2: 44.9;REH: 81.4 +ZFPM1 FOG, FOG1, ZC2HC11A, ZNF89A ENSG00000179588 Zinc finger protein, FOG family member 1 16 88453317-88537016 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046603 Enhanced Approved Nucleoplasm
Cytosol Urothelial cancer:4.24e-4 (favourable) Expressed in all Mixed stomach: 13.7 Cell line enhanced K-562: 26.0 +ALOX15B 15-LOX-2 ENSG00000179593 Arachidonate 15-lipoxygenase, type B 17 8039017-8049134 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010562 Enhanced Supported Plasma membrane
Cytosol Expressed in all Tissue enhanced breast: 145.0;prostate: 115.3 lung: 26.1 Group enriched 15 HHSteC: 6.5;HSkMC: 11.9;hTCEpi: 25.0 +PLD6 ENSG00000179598 Phospholipase D family member 6 17 17200995-17206315 Predicted membrane proteins Evidence at protein level HPA049345 Approved Pancreatic cancer:1.05e-4 (favourable) Expressed in all Tissue enhanced testis: 29.3 ovary: 8.9 Cell line enhanced HAP1: 42.7 +GPHB5 GPB5, ZLUT1 ENSG00000179600 Glycoprotein hormone beta 5 14 63312835-63318879 Predicted secreted proteins Evidence at protein level Not detected Not detected testis: 0.2 Not detected +GRM8 GLUR8, GPRC1H, mGlu8, MGLUR8 ENSG00000179603 Glutamate metabotropic receptor 8 7 126438598-127253294 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA051481 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 4.1 testis: 3.0 Group enriched 6 HAP1: 3.1;HEK 293: 1.4;NTERA-2: 3.9;RH-30: 2.2;SCLC-21H: 4.1;SH-SY5Y: 2.0;U-2 OS: 1.3 +CDC42EP4 BORG4, CEP4, KAIA1777, MGC17125, MGC3740 ENSG00000179604 CDC42 effector protein 4 17 73283624-73312175 Predicted intracellular proteins Evidence at protein level HPA023335, HPA024797 Approved Supported Enhanced Plasma membrane
Actin filaments
Microtubules Expressed in all Expressed in all cerebral cortex: 101.8 Mixed +OR2AP1 OR2AP1P ENSG00000179615 Olfactory receptor family 2 subfamily AP member 1 12 55574415-55575344 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR6C4 ENSG00000179626 Olfactory receptor family 6 subfamily C member 4 12 55551199-55552244 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZBTB42 ZNF925 ENSG00000179627 Zinc finger and BTB domain containing 42 14 104800596-104804712 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000703, HPA066961 Uncertain Supported Nucleus Renal cancer:2.30e-9 (favourable) Expressed in all Mixed prostate: 8.9 Cell line enhanced HDLM-2: 17.6;MCF7: 24.3;T-47d: 24.0 +LACC1 C13orf31, FAMIN, FLJ38725 ENSG00000179630 Laccase domain containing 1 13 43879284-43893932 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB034228, HPA040150, HPA044211 Uncertain Expressed in all Mixed testis: 17.1 Cell line enhanced TIME: 93.5 +MAF1 DKFZp586G1123 ENSG00000179632 MAF1 homolog, negative regulator of RNA polymerase III 8 144104499-144107611 Predicted intracellular proteins Evidence at protein level HPA024821, HPA058548 Uncertain Supported Nucleus
Nucleoli
Vesicles Liver cancer:7.09e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 142.6 Expressed in all +TPPP2 C14orf8, CT152, p18, p25beta ENSG00000179636 Tubulin polymerization promoting protein family member 2 14 21024109-21036276 Predicted intracellular proteins Evidence at protein level HPA004120 Enhanced Tissue enhanced Tissue enriched 46 testis: 309.1 liver: 6.7 Not detected +FCER1A FCE1A ENSG00000179639 Fc fragment of IgE receptor Ia 1 159289714-159308224 FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB022102, HPA036051, CAB055526 Approved Renal cancer:1.20e-4 (favourable) Expressed in all Mixed skin: 39.9 Cell line enriched 100 HEL: 401.2 +RPRML MGC43894 ENSG00000179673 Reprimo like 17 46978156-46979248 Predicted membrane proteins Evidence at transcript level HPA062668 Uncertain Tissue enhanced Tissue enriched 11 cerebral cortex: 8.6 epididymis: 0.7 Cell line enhanced AF22: 1.9;Daudi: 8.9;HEK 293: 3.5;NTERA-2: 1.9;SCLC-21H: 2.2 +ARL14 ARF7, FLJ22595 ENSG00000179674 ADP ribosylation factor like GTPase 14 3 160677159-160678452 Predicted intracellular proteins Evidence at protein level Lung cancer:2.64e-5 (unfavourable), Pancreatic cancer:6.71e-4 (unfavourable) Group enriched Tissue enhanced gallbladder: 209.1;stomach: 70.2 duodenum: 50.9 Group enriched 5 A-431: 8.4;CAPAN-2: 31.7;HaCaT: 7.9;RT4: 14.0 +OR6C2 OR6C67 ENSG00000179695 Olfactory receptor family 6 subfamily C member 2 12 55452214-55453152 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected epididymis,testis: 0.2 Not detected +WDR97 KIAA1875 ENSG00000179698 WD repeat domain 97 8 144107726-144118315 Predicted intracellular proteins Evidence at transcript level HPA059409 Uncertain Mixed Tissue enriched 9 testis: 1.1 adrenal gland: 0.1 Not detected +NLRP8 CLR19.2, NALP8, NOD16, PAN4 ENSG00000179709 NLR family pyrin domain containing 8 19 55947832-55988629 Predicted intracellular proteins Evidence at transcript level HPA056989 Uncertain Not detected Not detected breast,testis: 0.3 Not detected +PCED1B FAM113B, MGC16044 ENSG00000179715 PC-esterase domain containing 1B 12 47079603-47236662 Predicted intracellular proteins Evidence at protein level HPA043901 Approved Approved Golgi apparatus
Vesicles Renal cancer:4.55e-6 (unfavourable), Urothelial cancer:5.36e-5 (favourable) Expressed in all Mixed lymph node: 42.3 Cell line enhanced A549: 57.4;K-562: 43.7 +APOBEC3B FLJ21201, PHRBNL ENSG00000179750 Apolipoprotein B mRNA editing enzyme catalytic subunit 3B 22 38982347-38992804 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA056980, HPA066719 Approved Nucleoplasm Cervical cancer:2.58e-5 (favourable), Renal cancer:2.78e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 18.9 rectum: 13.9 Cell line enhanced A-431: 241.1;Karpas-707: 215.9 +SYCN FLJ27441, INSSA1, SYL ENSG00000179751 Syncollin 19 39202831-39204266 Predicted secreted proteins Evidence at protein level HPA047654 Enhanced Tissue enriched Tissue enriched 401 pancreas: 6057.1 ovary: 15.0 Not detected +PIPOX LPIPOX ENSG00000179761 Pipecolic acid and sarcosine oxidase 17 28950513-29057220 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Pancreatic cancer:1.49e-4 (favourable) Group enriched Group enriched 7 kidney: 137.9;liver: 235.9 epididymis: 26.0 Group enriched 5 AF22: 30.7;Hep G2: 65.9;NTERA-2: 61.7;RH-30: 85.6 +FOXS1 FKHL18, FREAC10 ENSG00000179772 Forkhead box S1 20 31844301-31845619 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042475 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.10e-8 (unfavourable) Expressed in all Mixed placenta: 7.0 Cell line enhanced EFO-21: 3.0;RH-30: 10.5;U-2 OS: 15.0;U-251 MG: 3.6 +ATOH7 bHLHa13, Math5 ENSG00000179774 Atonal bHLH transcription factor 7 10 68230624-68232103 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027008 Uncertain Not detected Tissue enriched 7 cerebral cortex: 2.2 endometrium,kidney,small intestine: 0.3 Cell line enriched 14 SCLC-21H: 9.1 +CDH5 7B4, CD144 ENSG00000179776 Cadherin 5 16 66366622-66404786 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB028366 Approved Renal cancer:5.14e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 335.1 lung: 120.5 Group enriched 5 HUVEC TERT2: 616.7;TIME: 522.0 +LRRC3B LRP15 ENSG00000179796 Leucine rich repeat containing 3B 3 26622806-26710776 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015568 Approved Group enriched Group enriched 7 cerebral cortex: 19.2;skeletal muscle: 3.9;testis: 13.0 endometrium,ovary: 1.6 Cell line enhanced NTERA-2: 1.6 +FAM216B C13orf30, FLJ40919 ENSG00000179813 Family with sequence similarity 216 member B 13 42781550-42791549 Predicted intracellular proteins Evidence at transcript level HPA040118 Uncertain Endometrial cancer:9.77e-4 (favourable) Group enriched Tissue enriched 8 fallopian tube: 122.8 lung: 15.1 Cell line enriched 13 U-87 MG: 1.7 +MRGPRX4 MRGX4 ENSG00000179817 MAS related GPR family member X4 11 18172837-18174280 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Tissue enriched Not detected all non-specific tissues: 0.0 Cell line enhanced SK-MEL-30: 1.1;WM-115: 1.8 +MYADM ENSG00000179820 Myeloid associated differentiation marker 19 53866223-53876437 Predicted membrane proteins, Transporters Evidence at protein level HPA056301 Approved Nuclear speckles Renal cancer:7.71e-7 (unfavourable), Lung cancer:8.15e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 260.7 Mixed +MRGPRX3 MRGX3 ENSG00000179826 MAS related GPR family member X3 11 18120955-18138480 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced salivary gland: 1.3 breast,testis: 0.7 Cell line enriched 7 HBEC3-KT: 10.4 +MROH1 HEATR7A, KIAA1833 ENSG00000179832 Maestro heat like repeat family member 1 8 144148016-144261940 Predicted intracellular proteins Evidence at protein level HPA044465 Approved Supported Renal cancer:3.65e-6 (favourable), Endometrial cancer:6.74e-4 (favourable) Expressed in all Expressed in all thyroid gland: 14.9 Mixed +SERTAD2 KIAA0127, Sei-2, TRIP-Br2 ENSG00000179833 SERTA domain containing 2 2 64631621-64751005 Predicted intracellular proteins Evidence at protein level HPA019021, HPA020904 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:1.70e-4 (unfavourable), Endometrial cancer:4.03e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 54.0 Expressed in all +AKAP5 AKAP75, AKAP79 ENSG00000179841 A-kinase anchoring protein 5 14 64465499-64474503 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004308, HPA053891 Enhanced Approved Nucleoplasm Mixed Tissue enriched 5 cerebral cortex: 22.5 rectum: 4.2 Cell line enhanced CACO-2: 9.0 +NKPD1 FLJ33600 ENSG00000179846 NTPase KAP family P-loop domain containing 1 19 45149750-45158737 Predicted membrane proteins Evidence at protein level HPA043339 Uncertain Mixed Tissue enriched 18 skin: 14.8 seminal vesicle: 0.8 Cell line enhanced hTCEpi: 1.1;SiHa: 1.5;U-266/70: 2.2 +GIPC3 C19orf64, DFNB15, DFNB72, DFNB95 ENSG00000179855 GIPC PDZ domain containing family member 3 19 3585553-3593541 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA061258, HPA067765 Approved Approved Nucleoplasm
Nuclear bodies
Golgi apparatus Mixed Mixed smooth muscle: 11.5 Cell line enhanced HeLa: 12.6;HMC-1: 10.5;THP-1: 15.5;WM-115: 44.4 +AC025335.1 ENSG00000179859 17 7913324-7916276 Predicted intracellular proteins Evidence at transcript level Cervical cancer:8.89e-5 (favourable) Expressed in all Tissue enriched 8 skin: 61.7 fallopian tube: 8.0 Cell line enhanced SiHa: 14.9 +CITED4 ENSG00000179862 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 1 40861051-40862366 Predicted intracellular proteins Evidence at protein level HPA056434 Approved Approved Vesicles Endometrial cancer:4.38e-5 (favourable) Expressed in all Mixed breast: 20.5 Cell line enhanced RPTEC TERT1: 67.0;THP-1: 176.9 +ABCA13 FLJ33876, FLJ33951 ENSG00000179869 ATP binding cassette subfamily A member 13 7 48171458-48647496 Predicted membrane proteins Evidence at transcript level HPA063601 Approved Vesicles
Centrosome
Cytosol Mixed Tissue enriched 10 bone marrow: 29.4 testis: 3.0 Cell line enhanced HDLM-2: 5.3;U-2 OS: 6.8 +NLRP11 CLR19.6, NALP11, NOD17, PAN10, PYPAF6 ENSG00000179873 NLR family pyrin domain containing 11 19 55785397-55836800 Predicted intracellular proteins Evidence at protein level HPA046402, HPA078027 Uncertain Supported Cytosol Not detected Tissue enhanced epididymis: 1.4;testis: 1.3 tonsil: 0.6 Group enriched 18 Daudi: 82.3;Karpas-707: 17.0;RPMI-8226: 44.9;U-266/70: 83.8;U-266/84: 35.2;U-698: 57.1 +TIGD5 FLJ14926 ENSG00000179886 Tigger transposable element derived 5 8 143597835-143603224 Predicted intracellular proteins Evidence at protein level Renal cancer:9.16e-5 (favourable), Liver cancer:7.68e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 2.2 Mixed +PDXDC1 KIAA0251 ENSG00000179889 Pyridoxal dependent decarboxylase domain containing 1 16 14974591-15139339 Predicted intracellular proteins Evidence at protein level HPA047369, HPA049121, HPA051484 Approved Enhanced Golgi apparatus
Vesicles Renal cancer:3.13e-4 (favourable) Expressed in all Expressed in all testis: 105.7 Expressed in all +C1orf194 ENSG00000179902 Chromosome 1 open reading frame 194 1 109105951-109113857 Predicted intracellular proteins Evidence at protein level HPA031144, HPA049684 Enhanced Uncertain Nuclear speckles
Cytosol Endometrial cancer:1.36e-4 (favourable) Group enriched Group enriched 31 fallopian tube: 198.1;testis: 199.1 lung: 6.4 Cell line enhanced AF22: 1.5;SCLC-21H: 2.5 +ZNF154 pHZ-92 ENSG00000179909 Zinc finger protein 154 19 57697367-57709194 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Mixed parathyroid gland: 9.5 Cell line enhanced AF22: 5.2;MOLT-4: 3.6;NTERA-2: 2.9 +R3HDM2 KIAA1002 ENSG00000179912 R3H domain containing 2 12 57253762-57431005 Predicted intracellular proteins Evidence at protein level HPA038327, HPA038328 Approved Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 51.8 Expressed in all +B3GNT3 B3GN-T3, B3GNT-3, beta3Gn-T3, HP10328, TMEM3 ENSG00000179913 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 19 17794828-17813082 Enzymes, Predicted secreted proteins Evidence at protein level HPA024298 Enhanced Lung cancer:4.25e-5 (unfavourable), Pancreatic cancer:2.16e-4 (unfavourable) Mixed Tissue enhanced rectum: 50.8 colon: 48.8 Cell line enhanced A-431: 43.3;BEWO: 45.1;CAPAN-2: 113.3;RT4: 37.2;SK-BR-3: 32.5 +ITLN1 FLJ20022, hIntL, HL-1, ITLN, LFR ENSG00000179914 Intelectin 1 1 160876539-160885170 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB012652, HPA063275, HPA067326 Enhanced Tissue enhanced Tissue enhanced colon: 447.7;rectum: 1428.1;small intestine: 468.9 duodenum: 276.3 Cell line enhanced HEL: 2.3;HL-60: 1.5;U-937: 5.7 +NRXN1 Hs.22998, KIAA0578 ENSG00000179915 Neurexin 1 2 49918505-51225575 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA071400 Approved Nucleoli
Plasma membrane Tissue enriched Tissue enriched 12 cerebral cortex: 154.0 seminal vesicle: 12.9 Cell line enriched 9 SCLC-21H: 42.8 +SEPHS2 SPS2, SPS2b ENSG00000179918 Selenophosphate synthetase 2 16 30443631-30446181 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047931 Approved Approved Nucleoplasm Renal cancer:4.35e-8 (favourable) Expressed in all Expressed in all liver: 180.4 Expressed in all +OR10A7 ENSG00000179919 Olfactory receptor family 10 subfamily A member 7 12 55221025-55221975 G-protein coupled receptors, Predicted membrane proteins No evidence HPA055111 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +GPBAR1 BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5 ENSG00000179921 G protein-coupled bile acid receptor 1 2 218259496-218263859 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA062890 Enhanced Tissue enhanced Tissue enhanced gallbladder: 26.9;smooth muscle: 14.0 adipose tissue: 9.9 Cell line enhanced HHSteC: 1.5;SCLC-21H: 1.1;U-937: 1.4 +ZNF784 MGC75238 ENSG00000179922 Zinc finger protein 784 19 55620742-55624601 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059676 Uncertain Approved Nucleus Urothelial cancer:1.02e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 14.7 Expressed in all +ZNF648 FLJ46813 ENSG00000179930 Zinc finger protein 648 1 182054570-182061712 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA053897 Uncertain Not detected Not detected ovary,testis: 0.6 Cell line enriched 87 HMC-1: 31.7 +C14orf119 FLJ20671 ENSG00000179933 Chromosome 14 open reading frame 119 14 23094765-23100462 Predicted intracellular proteins Evidence at protein level HPA003638 Uncertain Supported Mitochondria
Cytosol Thyroid cancer:3.30e-5 (favourable), Liver cancer:5.42e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 70.9 Expressed in all +CCR8 CDw198, CKR-L1, CMKBR8, CMKBRL2, CY6, GPR-CY6, TER1 ENSG00000179934 C-C motif chemokine receptor 8 3 39329706-39333511 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042383 Supported Mixed Tissue enhanced urinary bladder: 2.3 appendix: 1.7 Cell line enriched 22 HDLM-2: 104.4 +GOLGA8J ENSG00000179938 Golgin A8 family member J 15 30083053-30093499 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +BBS10 C12orf58, FLJ23560 ENSG00000179941 Bardet-Biedl syndrome 10 12 76344474-76348442 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047954, HPA058743 Approved Uncertain Nucleoplasm Expressed in all Mixed cerebral cortex: 16.7 Expressed in all +FIZ1 FLJ14768, ZNF798 ENSG00000179943 FLT3 interacting zinc finger 1 19 55591371-55601970 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA074026 Approved Nucleus Urothelial cancer:2.02e-4 (favourable), Pancreatic cancer:8.42e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 19.6 Expressed in all +PUF60 FIR, RoBPI, SIAHBP1 ENSG00000179950 Poly(U) binding splicing factor 60 8 143816344-143829859 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045733, HPA052096, HPA059714 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all testis: 26.1 Expressed in all +SSC5D FLJ35258, S5D-SRCRB ENSG00000179954 Scavenger receptor cysteine rich family member with 5 domains 19 55488404-55519098 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042008 Approved Approved Nucleoplasm
Cytosol Renal cancer:4.26e-8 (unfavourable) Mixed Mixed smooth muscle: 32.1 Cell line enhanced ASC TERT1: 22.1;BJ: 26.4;fHDF/TERT166: 24.8;U-87 MG: 32.1 +DCTPP1 CDA03, MGC5627, RS21C6, XTP3TPA ENSG00000179958 DCTP pyrophosphatase 1 16 30423619-30430075 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002832 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:9.71e-9 (favourable), Breast cancer:1.64e-5 (unfavourable), Liver cancer:6.28e-4 (unfavourable) Expressed in all Expressed in all rectum: 64.1 Expressed in all +ZNF771 DSC43 ENSG00000179965 Zinc finger protein 771 16 30407297-30431108 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030730, HPA046672, HPA059398 Uncertain Approved Nucleus
Nucleoli Expressed in all Mixed cerebral cortex: 7.0 Expressed in all +CRIPAK FLJ34443 ENSG00000179979 Cysteine rich PAK1 inhibitor 4 1391552-1395989 Predicted intracellular proteins Evidence at protein level Endometrial cancer:1.55e-4 (favourable), Head and neck cancer:4.37e-4 (favourable) Expressed in all Mixed skin: 15.0 Mixed +TSHZ1 NY-CO-33, SDCCAG33, TSH1 ENSG00000179981 Teashirt zinc finger homeobox 1 18 75210755-75289950 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006982 Approved Approved Nucleoplasm Thyroid cancer:1.71e-5 (unfavourable) Expressed in all Expressed in all ovary: 46.4 Cell line enhanced HDLM-2: 45.8 +PSTK C10orf89, MGC35392 ENSG00000179988 Phosphoseryl-tRNA kinase 10 122954381-122997513 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037780, HPA037781 Approved Approved Nucleoli
Nuclear bodies
Actin filaments Mixed Mixed testis: 5.9 Mixed +SOCS4 SOCS7 ENSG00000180008 Suppressor of cytokine signaling 4 14 55027230-55049488 Predicted intracellular proteins Evidence at protein level CAB013478, HPA057961 Approved Approved Nucleus
Cytosol Expressed in all Mixed thyroid gland: 12.5 Expressed in all +ZADH2 MGC45594 ENSG00000180011 Zinc binding alcohol dehydrogenase domain containing 2 18 75195108-75209348 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021468, HPA053646 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Renal cancer:1.02e-6 (favourable), Thyroid cancer:1.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 52.3 Expressed in all +OR1E1 HGM071, OR13-66, OR17-2, OR17-32, OR1E5, OR1E6, OR1E9P ENSG00000180016 Olfactory receptor family 1 subfamily E member 1 17 3397104-3398410 G-protein coupled receptors, Predicted membrane proteins, Transporters No evidence Not detected Not detected placenta,spleen,testis: 0.1 Not detected +ZNF48 DKFZp762K013, FLJ31751, MGC43952, ZNF553 ENSG00000180035 Zinc finger protein 48 16 30378106-30400108 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023806 Uncertain Supported Mitochondria Pancreatic cancer:1.20e-6 (favourable), Renal cancer:7.50e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 14.0 Expressed in all +FAM71E2 C19orf16, DKFZp434G1729 ENSG00000180043 Family with sequence similarity 71 member E2 19 55354908-55363260 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 236 testis: 23.6 all non-specific tissues: 0.0 Cell line enriched 10 SCLC-21H: 1.0 +C3orf80 ENSG00000180044 Chromosome 3 open reading frame 80 3 160225496-160228213 Predicted membrane proteins Evidence at transcript level HPA047439 Uncertain Mixed Tissue enhanced cerebral cortex: 9.8 esophagus: 2.7 Cell line enriched 6 HMC-1: 126.0 +NKX2-6 CSX2, NKX4-2 ENSG00000180053 NK2 homeobox 6 8 23702451-23706598 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Cell line enhanced hTEC/SVTERT24-B: 3.6 +TMEM150B TMEM224, TTN2 ENSG00000180061 Transmembrane protein 150B 19 55312801-55334048 Predicted membrane proteins Evidence at transcript level Renal cancer:6.14e-6 (unfavourable) Tissue enhanced Tissue enhanced duodenum: 69.8;small intestine: 66.5 lung: 18.9 Cell line enhanced CACO-2: 7.6;HMC-1: 4.0;U-937: 16.3 +ANKRD18A FLJ35740, KIAA2015 ENSG00000180071 Ankyrin repeat domain 18A 9 38571358-38620660 Predicted intracellular proteins Evidence at protein level HPA046346, HPA046695, HPA049923, HPA051288 Uncertain Supported Nucleoli
Cytosol Mixed Tissue enhanced bone marrow: 11.3;testis: 10.2 thyroid gland: 3.5 Cell line enhanced HL-60: 13.8 +WFDC11 WAP11 ENSG00000180083 WAP four-disulfide core domain 11 20 45648563-45670270 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 14 epididymis: 115.8 testis: 8.5 Group enriched 6 HeLa: 5.5;RPMI-8226: 3.6;U-937: 1.1 +TMEM86B MGC30208 ENSG00000180089 Transmembrane protein 86B 19 55226639-55229264 Enzymes, Predicted membrane proteins Evidence at protein level HPA057689 Uncertain Approved Midbody
Centrosome Pancreatic cancer:9.97e-6 (favourable), Liver cancer:3.13e-4 (favourable) Tissue enriched Mixed gallbladder: 6.6 Mixed +OR3A1 OLFRA03, OR17-40, OR40 ENSG00000180090 Olfactory receptor family 3 subfamily A member 1 17 3291635-3292600 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced testis: 1.7 epididymis: 0.3 Cell line enriched 21 HDLM-2: 20.9 +SEPT1 DIFF6, PNUTL3 ENSG00000180096 Septin 1 16 30378133-30395991 Predicted intracellular proteins Evidence at protein level HPA041566, HPA060339 Enhanced Uncertain Actin filaments Renal cancer:2.40e-7 (unfavourable), Endometrial cancer:3.04e-5 (favourable), Lung cancer:7.24e-5 (favourable), Cervical cancer:9.72e-5 (favourable), Pancreatic cancer:2.22e-4 (favourable), Head and neck cancer:6.63e-4 (favourable) Expressed in all Tissue enhanced lymph node: 16.3;spleen: 11.3 tonsil: 6.0 Cell line enhanced Daudi: 27.2;MOLT-4: 53.0;REH: 35.4;U-266/84: 23.4 +TRNAU1AP FLJ20503, SECP43, TRSPAP1 ENSG00000180098 TRNA selenocysteine 1 associated protein 1 1 28553085-28578545 Predicted intracellular proteins Evidence at protein level HPA032068, HPA032069 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.16e-5 (unfavourable), Liver cancer:8.64e-5 (unfavourable), Endometrial cancer:2.22e-4 (favourable), Thyroid cancer:9.45e-4 (favourable) Expressed in all Mixed parathyroid gland: 8.3 Expressed in all +EXOC3 SEC6L1, Sec6p ENSG00000180104 Exocyst complex component 3 5 443158-471937 Predicted intracellular proteins, Transporters Evidence at protein level HPA037880 Approved Nucleoplasm
Mitochondria Pancreatic cancer:1.54e-4 (favourable) Expressed in all Expressed in all testis: 58.5 Expressed in all +TDRD6 bA446F17.4, CT41.2, NY-CO-45, SPATA36 ENSG00000180113 Tudor domain containing 6 6 46687875-46704319 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 6 testis: 42.8;thyroid gland: 10.1 appendix,lymph node: 4.7 Not detected +C12orf40 FLJ40126 ENSG00000180116 Chromosome 12 open reading frame 40 12 39626167-39908300 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 77 testis: 15.7 tonsil: 0.2 Cell line enriched 7 K-562: 2.4 +CSNK1A1L MGC33182 ENSG00000180138 Casein kinase 1 alpha 1 like 13 37103259-37105664 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA051334 Approved Cytosol Not detected Tissue enriched 16 testis: 6.4 bone marrow: 0.3 Not detected +LYNX1 SLURP2 ENSG00000180155 Ly6/neurotoxin 1 8 142771197-142777810 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Renal cancer:2.82e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 94.6 parathyroid gland: 58.6 Cell line enhanced BJ: 6.9;fHDF/TERT166: 7.9;HHSteC: 6.9;T-47d: 6.7 +TH DYT5b ENSG00000180176 Tyrosine hydroxylase 11 2163929-2171877 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB002522, HPA013768, HPA061003, CAB072340 Enhanced Supported Tissue enhanced Tissue enriched 81 adrenal gland: 259.8 adipose tissue: 3.2 Group enriched 26 PC-3: 54.8;SK-BR-3: 15.7 +MED14 CRSP150, CRSP2, CSRP, CXorf4, EXLM1, RGR1, TRAP170 ENSG00000180182 Mediator complex subunit 14 X 40648306-40735858 Predicted intracellular proteins Evidence at protein level HPA064182 Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 32.3 Expressed in all +FAHD1 C16orf36, DKFZP566J2046 ENSG00000180185 Fumarylacetoacetate hydrolase domain containing 1 16 1826941-1840207 Enzymes, Predicted intracellular proteins Evidence at protein level CAB025530, HPA043226, HPA043534 Enhanced Enhanced Nucleus
Mitochondria Renal cancer:2.80e-14 (favourable), Colorectal cancer:8.27e-4 (favourable) Expressed in all Expressed in all kidney: 66.1 Expressed in all +TDRP C8orf42, INM01, TDRP1, TDRP2 ENSG00000180190 Testis development related protein 8 489792-545781 Predicted intracellular proteins Evidence at protein level HPA008462 Approved Supported Vesicles
Cytosol Endometrial cancer:1.52e-4 (unfavourable), Pancreatic cancer:9.37e-4 (favourable) Expressed in all Mixed placenta: 46.8 Cell line enhanced BEWO: 48.4 +RCC1 CHC1 ENSG00000180198 Regulator of chromosome condensation 1 1 28505943-28539300 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015413, HPA027573, HPA027574 Enhanced Supported Nucleus
Nuclear membrane Renal cancer:2.43e-11 (unfavourable), Liver cancer:1.91e-5 (unfavourable) Expressed in all Expressed in all testis: 63.8 Expressed in all +WFDC9 dJ688G8.2, WAP9 ENSG00000180205 WAP four-disulfide core domain 9 20 45607939-45631268 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 405 epididymis: 1257.7 seminal vesicle: 3.1 Not detected +MYLPF HUMMLC2B, MRLC2, MYL11 ENSG00000180209 Myosin light chain, phosphorylatable, fast skeletal muscle 16 30370934-30377991 Predicted intracellular proteins Evidence at protein level HPA039262, HPA055059 Enhanced Tissue enhanced Tissue enriched 95 skeletal muscle: 6541.1 esophagus: 69.1 Group enriched 18 BEWO: 68.9;HSkMC: 114.2 +F2 ENSG00000180210 Coagulation factor II, thrombin 11 46719180-46739506 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016780, CAB018650, HPA051476, HPA054698 Enhanced Renal cancer:6.75e-12 (unfavourable) Tissue enriched Tissue enriched 1472 liver: 627.3 testis: 0.4 Cell line enriched 18 Hep G2: 186.7 +FAM71C MGC39520 ENSG00000180219 Family with sequence similarity 71 member C 12 99647753-99650046 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 312 testis: 31.2 all non-specific tissues: 0.0 Not detected +PRKRA DYT16, HSD14, PACT, RAX ENSG00000180228 Protein activator of interferon induced protein kinase EIF2AK2 2 178431414-178451512 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004648, HPA034996, HPA034997 Approved Supported Nucleoplasm
Cytosol Liver cancer:8.33e-5 (unfavourable), Testis cancer:5.45e-4 (favourable) Expressed in all Expressed in all testis: 56.2 Expressed in all +ZNRF2 RNF202 ENSG00000180233 Zinc and ring finger 2 7 30284307-30367692 Enzymes, Predicted intracellular proteins Evidence at protein level HPA072244 Approved Renal cancer:2.29e-4 (favourable), Endometrial cancer:7.68e-4 (unfavourable), Thyroid cancer:8.71e-4 (favourable) Expressed in all Expressed in all testis: 39.7 Expressed in all +RRH peropsin ENSG00000180245 Retinal pigment epithelium-derived rhodopsin homolog 4 109827994-109844604 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected breast,cerebral cortex,skin: 0.5 Cell line enhanced U-266/84: 1.0 +SLC9A4 NHE4 ENSG00000180251 Solute carrier family 9 member A4 2 102473303-102533972 Predicted membrane proteins, Transporters Evidence at protein level HPA036096 Supported Approved Nucleoplasm
Plasma membrane Mixed Tissue enriched 5 stomach: 51.3 kidney: 9.5 Cell line enhanced EFO-21: 1.3;HDLM-2: 2.2;RT4: 3.4 +ZNF816 ZNF816A ENSG00000180257 Zinc finger protein 816 19 52949379-52962911 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA042466 Uncertain Uncertain Nucleoli Expressed in all Mixed prostate: 20.8 Cell line enhanced RT4: 42.8 +PRNT M8 ENSG00000180259 Prion protein (testis specific) 20 4731282-4740668 Predicted secreted proteins Evidence at transcript level HPA045000 Uncertain Not detected Tissue enriched 110 testis: 10.9 all non-specific tissues: 0.0 Not detected +FGD6 FLJ11183, ZFYVE24 ENSG00000180263 FYVE, RhoGEF and PH domain containing 6 12 95076749-95217482 Predicted intracellular proteins Evidence at protein level HPA007974 Approved Approved Vesicles Renal cancer:5.46e-6 (unfavourable), Pancreatic cancer:4.62e-5 (unfavourable), Prostate cancer:9.83e-4 (unfavourable) Expressed in all Mixed skin: 9.4 Mixed +ADGRD2 GPR144, PGR24 ENSG00000180264 Adhesion G protein-coupled receptor D2 9 124451425-124478589 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced seminal vesicle: 1.8 skin: 0.5 Not detected +GPR139 PGR3 ENSG00000180269 G protein-coupled receptor 139 16 20031485-20073917 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA046596 Uncertain Not detected Not detected endometrium: 0.3 Not detected +PLD5 FLJ40773 ENSG00000180287 Phospholipase D family member 5 1 242082986-242524696 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA028389, HPA050367 Uncertain Approved Vesicles
Mitochondria
Cytosol Tissue enhanced Tissue enhanced seminal vesicle: 4.2 cerebral cortex: 4.1 Cell line enhanced AF22: 10.2;HDLM-2: 5.0;SH-SY5Y: 3.0;U-2 OS: 3.6 +OAZ2 ENSG00000180304 Ornithine decarboxylase antizyme 2 15 64687573-64703281 Predicted intracellular proteins Evidence at protein level HPA047694 Uncertain Approved Golgi apparatus Colorectal cancer:9.05e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 118.1 Expressed in all +WFDC10A C20orf146, dJ688G8.3, WAP10 ENSG00000180305 WAP four-disulfide core domain 10A 20 45629526-45631196 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 354 epididymis: 175.8 seminal vesicle: 0.4 Not detected +PNPLA1 dJ50J22.1, FLJ38755 ENSG00000180316 Patatin like phospholipase domain containing 1 6 36243203-36312229 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037853 Uncertain Intermediate filaments Mixed Tissue enriched 6 skin: 35.0 kidney: 5.6 Cell line enriched 5 U-937: 15.5 +ALX1 CART1 ENSG00000180318 ALX homeobox 1 12 85280107-85301784 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001598, HPA018905 Uncertain Supported Nucleoplasm
Nuclear bodies
Golgi apparatus Tissue enriched Tissue enhanced epididymis: 4.3;kidney: 3.1 ovary: 1.8 Cell line enhanced HEK 293: 19.4;HUVEC TERT2: 13.0;SK-MEL-30: 20.2;THP-1: 11.5;WM-115: 13.3 +CCDC43 FLJ31795 ENSG00000180329 Coiled-coil domain containing 43 17 44673069-44689779 Predicted intracellular proteins Evidence at protein level HPA023391 Approved Enhanced Cytosol Head and neck cancer:3.42e-5 (unfavourable), Liver cancer:1.33e-4 (unfavourable), Pancreatic cancer:3.19e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 26.1 Expressed in all +KCTD4 bA321C24.3 ENSG00000180332 Potassium channel tetramerization domain containing 4 13 45192853-45194717 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040734 Uncertain Approved Microtubule organizing center Group enriched Group enriched 10 cerebral cortex: 17.7;skin: 3.7 gallbladder: 1.1 Cell line enhanced RPTEC TERT1: 8.8;U-138 MG: 13.7;U-87 MG: 27.1 +MEIOC C17orf104, FLJ35848 ENSG00000180336 Meiosis specific with coiled-coil domain 17 44656404-44690308 Predicted intracellular proteins Evidence at protein level HPA027266 Enhanced Uncertain Cell Junctions Not detected Tissue enriched 52 testis: 86.2 cerebral cortex: 1.6 Cell line enhanced HAP1: 17.4;HMC-1: 22.4;SiHa: 10.1 +FZD2 ENSG00000180340 Frizzled class receptor 2 17 44557459-44559570 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA057667 Uncertain Approved Nucleus
Nuclear bodies
Cell Junctions Expressed in all Mixed placenta: 4.9 Mixed +TIGD2 ENSG00000180346 Tigger transposable element derived 2 4 89111500-89114899 Predicted intracellular proteins Evidence at protein level HPA054844, HPA071168 Uncertain Approved Nuclear bodies Colorectal cancer:4.59e-4 (favourable), Urothelial cancer:7.02e-4 (favourable) Expressed in all Mixed parathyroid gland: 18.0 Expressed in all +CCDC129 FLJ38344 ENSG00000180347 Coiled-coil domain containing 129 7 31514071-31658720 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA024103 Uncertain Uncertain Nucleoplasm Not detected Tissue enhanced cervix, uterine: 2.6;salivary gland: 2.4 testis: 2.1 Cell line enhanced U-2 OS: 1.6 +HCLS1 CTTNL, HS1 ENSG00000180353 Hematopoietic cell-specific Lyn substrate 1 3 121631399-121660927 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019143 Supported Supported Plasma membrane
Cytosol Expressed in all Expressed in all spleen: 271.3 Cell line enhanced HMC-1: 319.6;U-266/70: 275.0;U-698: 256.8 +MTURN C7orf41, Ells1, FLJ25903 ENSG00000180354 Maturin, neural progenitor differentiation regulator homolog 7 30134810-30162762 Predicted intracellular proteins Evidence at protein level HPA029507 Approved Approved Cytosol Renal cancer:7.64e-13 (favourable) Expressed in all Expressed in all cerebral cortex: 351.3 Cell line enhanced HEL: 86.3;SCLC-21H: 80.0 +ZNF609 KIAA0295 ENSG00000180357 Zinc finger protein 609 15 64460742-64686068 Predicted intracellular proteins Evidence at protein level HPA040742, HPA040832 Approved Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 40.7 Expressed in all +PAK2 PAK65, PAKgamma ENSG00000180370 P21 (RAC1) activated kinase 2 3 196739857-196832647 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB007794 Approved Enhanced Nucleus
Vesicles Pancreatic cancer:3.36e-4 (unfavourable), Prostate cancer:9.58e-4 (unfavourable) Expressed in all Expressed in all spleen: 60.1 Expressed in all +CCDC66 DKFZp686C0433 ENSG00000180376 Coiled-coil domain containing 66 3 56557161-56621818 Predicted intracellular proteins Evidence at protein level HPA044185 Uncertain Approved Cell Junctions
Midbody ring
Microtubule organizing center Expressed in all Mixed fallopian tube: 9.6 Expressed in all +DEFB124 DEFB-24 ENSG00000180383 Defensin beta 124 20 31465506-31476757 Predicted secreted proteins Evidence at transcript level HPA051046 Uncertain Tissue enhanced Tissue enhanced fallopian tube: 8.9;testis: 5.7 endometrium: 5.4 Group enriched 6 HEL: 2.4;HMC-1: 1.3;U-2 OS: 1.1;WM-115: 5.7 +KRTAP9-7 KAP9.7, KRTAP9L1 ENSG00000180386 Keratin associated protein 9-7 17 41275659-41276697 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ATP5EP2 ENSG00000180389 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2 13 27945206-27945590 Predicted intracellular proteins No evidence Liver cancer:2.36e-4 (unfavourable) Expressed in all Not detected stomach: 0.2 Not detected +MCFD2 F5F8D, LMAN1IP, SDNSF ENSG00000180398 Multiple coagulation factor deficiency 2 2 46901870-46941855 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB022410, HPA034593 Supported Urothelial cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 206.7 Expressed in all +HARBI1 C11orf77, FLJ32675 ENSG00000180423 Harbinger transposase derived 1 11 46602861-46617909 Predicted intracellular proteins Evidence at protein level HPA038671, HPA045457 Uncertain Enhanced Plasma membrane
Cytosol Expressed in all Tissue enhanced testis: 21.7 parathyroid gland: 5.4 Expressed in all +DEFB123 DEFB-23 ENSG00000180424 Defensin beta 123 20 31440519-31450257 Predicted secreted proteins Evidence at protein level Tissue enriched Group enriched 438 epididymis: 108.1;testis: 178.0 small intestine: 0.3 Not detected +C11orf71 FLJ20010 ENSG00000180425 Chromosome 11 open reading frame 71 11 114391443-114400511 Predicted intracellular proteins Evidence at protein level HPA063943, HPA074787 Supported Nucleoplasm Renal cancer:7.01e-9 (favourable), Endometrial cancer:6.94e-4 (favourable) Expressed in all Expressed in all testis: 64.0 Mixed +CYP8B1 CYP12 ENSG00000180432 Cytochrome P450 family 8 subfamily B member 1 3 42856005-42876165 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 14 liver: 190.6 kidney: 13.7 Cell line enhanced BEWO: 2.2 +OR6K6 ENSG00000180433 Olfactory receptor family 6 subfamily K member 6 1 158754720-158755891 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +SERTM1 C13orf36 ENSG00000180440 Serine rich and transmembrane domain containing 1 13 36673912-36697839 Predicted membrane proteins Evidence at protein level HPA054814, HPA070485 Uncertain Supported Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 47.6;endometrium: 37.7;fallopian tube: 29.6 smooth muscle: 24.8 Cell line enhanced HAP1: 1.2;HEK 293: 1.3;NTERA-2: 3.5;SH-SY5Y: 2.1 +GAS1 ENSG00000180447 Growth arrest specific 1 9 86944363-86947189 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB024164, HPA036085, HPA066902 Approved Approved Nuclear speckles Thyroid cancer:1.13e-5 (unfavourable), Renal cancer:1.96e-5 (unfavourable), Colorectal cancer:1.55e-4 (unfavourable), Stomach cancer:8.26e-4 (unfavourable) Expressed in all Tissue enhanced endometrium: 110.8 smooth muscle: 74.4 Cell line enhanced AN3-CA: 44.7;BJ hTERT+: 53.4;RH-30: 95.7 +ARHGAP45 HA-1, HMHA1, KIAA0223 ENSG00000180448 Rho GTPase activating protein 45 19 1065923-1086628 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA019816 Enhanced Endometrial cancer:6.02e-4 (favourable), Head and neck cancer:7.82e-4 (favourable) Expressed in all Tissue enhanced appendix: 56.4;lymph node: 66.6;spleen: 77.8 bone marrow: 44.0 Cell line enhanced Karpas-707: 72.0;U-266/70: 99.7 +OR10Q1 ENSG00000180475 Olfactory receptor family 10 subfamily Q member 1 11 58227882-58228918 G-protein coupled receptors, Predicted membrane proteins No evidence HPA046968 Uncertain Not detected Not detected placenta: 0.1 Not detected +ZNF571 HSPC059 ENSG00000180479 Zinc finger protein 571 19 37554782-37594790 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA054762 Approved Nucleus
Nucleoli
Plasma membrane Mixed Tissue enriched 6 thyroid gland: 130.6 parathyroid gland: 21.6 Mixed +GLIPR1L2 MGC39497 ENSG00000180481 GLI pathogenesis related 1 like 2 12 75391070-75432688 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039795, HPA039866 Enhanced Mixed Tissue enriched 8 testis: 84.9 parathyroid gland: 10.9 Cell line enhanced SK-BR-3: 4.4;U-2 OS: 7.8 +DEFB119 DEFB-19, DEFB-20, DEFB120 ENSG00000180483 Defensin beta 119 20 31377164-31390603 Predicted secreted proteins Evidence at protein level HPA043059 Supported Tissue enriched Group enriched 3499 epididymis: 2335.6;testis: 472.8 duodenum: 0.4 Not detected +MIGA1 FAM73A, FLJ35093 ENSG00000180488 Mitoguardin 1 1 77779624-77879539 Predicted membrane proteins Evidence at protein level HPA017589 Approved Supported Mitochondria Expressed in all Expressed in all parathyroid gland: 32.7 Expressed in all +KCNE1 ISK, JLNS2, LQT5, minK ENSG00000180509 Potassium voltage-gated channel subfamily E regulatory subunit 1 21 34446688-34512275 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced fallopian tube: 16.6 heart muscle: 3.6 Cell line enhanced BJ hTERT+ SV40 Large T+: 1.2;CACO-2: 3.3 +PRR26 C10orf108, FLJ38681 ENSG00000180525 Proline rich 26 10 649948-669581 Predicted intracellular proteins Evidence at transcript level HPA066037 Uncertain Mixed Mixed gallbladder: 7.9 Cell line enhanced CACO-2: 1.4;CAPAN-2: 1.2;EFO-21: 1.4;RPTEC TERT1: 1.9 +NRIP1 RIP140 ENSG00000180530 Nuclear receptor interacting protein 1 21 14961235-15065936 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046571, HPA060036 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all cervix, uterine: 38.9 Cell line enhanced REH: 87.8 +ZSCAN4 FLJ35105, ZNF494 ENSG00000180532 Zinc finger and SCAN domain containing 4 19 57668935-57679152 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA006491 Uncertain Tissue enhanced Tissue enhanced stomach: 2.5 placenta: 1.2 Not detected +BHLHA15 bHLHa15, BHLHB8, MIST1 ENSG00000180535 Basic helix-loop-helix family member a15 7 98211427-98212979 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB034083, HPA047834 Enhanced Approved Nucleoplasm
Golgi apparatus Tissue enhanced Group enriched 7 pancreas: 85.5;salivary gland: 54.0 prostate: 9.3 Group enriched 8 Karpas-707: 27.3;RPMI-8226: 50.7;U-266/70: 63.7 +RNF182 MGC33993 ENSG00000180537 Ring finger protein 182 6 13924446-13980302 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012309 Approved Approved Nucleus
Golgi apparatus
Vesicles Endometrial cancer:4.66e-5 (unfavourable) Mixed Tissue enhanced cerebral cortex: 14.6 testis: 6.9 Cell line enhanced HeLa: 57.3;RPTEC TERT1: 51.0 +TSPYL5 KIAA1750 ENSG00000180543 TSPY like 5 8 97273474-97277964 Predicted intracellular proteins Evidence at protein level HPA031347 Enhanced Approved Golgi apparatus
Cytosol Renal cancer:1.40e-5 (favourable), Breast cancer:1.21e-4 (favourable) Expressed in all Tissue enhanced testis: 81.4 ovary: 30.4 Cell line enhanced SCLC-21H: 70.7;SH-SY5Y: 49.4 +FUT7 ENSG00000180549 Fucosyltransferase 7 9 137030174-137033010 Predicted intracellular proteins Evidence at protein level HPA042780 Approved Golgi apparatus Mixed Tissue enhanced lymph node: 3.7;spleen: 2.6 bone marrow,tonsil: 2.0 Group enriched 7 NB-4: 10.4;THP-1: 14.0;U-937: 9.1 +HIST1H2AC H2AFL ENSG00000180573 Histone cluster 1 H2A family member c 6 26124145-26139116 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA041189 Supported Expressed in all Expressed in all prostate: 50.4 Cell line enhanced SiHa: 77.5;U-2 OS: 74.5 +EIF2S3L ENSG00000180574 Putative eukaryotic translation initiation factor 2 subunit 3-like protein 12 10505602-10523135 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced testis: 4.4 duodenum: 1.0 Cell line enhanced HaCaT: 2.3;HL-60: 3.9;MOLT-4: 3.4;RH-30: 2.9 +SKIDA1 C10orf140, FLJ45187 ENSG00000180592 SKI/DACH domain containing 1 10 21513478-21526368 Predicted intracellular proteins Evidence at protein level HPA039208, HPA040439 Uncertain Mixed Tissue enhanced parathyroid gland: 3.9 testis: 3.1 Cell line enhanced AF22: 25.8;BEWO: 11.6 +HIST1H2BC H2B.1, H2B/l, H2BFL ENSG00000180596 Histone cluster 1 H2B family member c 6 26114873-26123926 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Renal cancer:1.75e-5 (unfavourable), Pancreatic cancer:9.01e-4 (unfavourable) Expressed in all Tissue enhanced prostate: 35.5 bone marrow: 16.6 Cell line enhanced SiHa: 80.4;U-2 OS: 53.7 +MB21D2 C3orf59 ENSG00000180611 Mab-21 domain containing 2 3 192796815-192918161 Predicted intracellular proteins Evidence at protein level HPA044026 Uncertain Approved Cytosol Endometrial cancer:3.74e-5 (unfavourable), Head and neck cancer:9.94e-4 (unfavourable) Mixed Mixed placenta: 17.1 Cell line enhanced HDLM-2: 97.0 +GSX2 Gsh2 ENSG00000180613 GS homeobox 2 4 54099523-54102505 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enriched Not detected testis: 0.4 Not detected +SSTR2 ENSG00000180616 Somatostatin receptor 2 17 73165012-73176633 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA007264 Uncertain Supported Cytosol Renal cancer:9.04e-7 (unfavourable), Pancreatic cancer:6.63e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 22.9 spleen: 5.8 Cell line enriched 9 SCLC-21H: 14.9 +ZNF594 KIAA1871 ENSG00000180626 Zinc finger protein 594 17 5179536-5191883 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060283, HPA067178, HPA069360 Enhanced Nucleus Mixed Mixed ovary,parathyroid gland: 13.9 Mixed +PCGF5 MGC16202, RNF159 ENSG00000180628 Polycomb group ring finger 5 10 91163012-91284331 Predicted intracellular proteins Evidence at protein level HPA038349 Approved Supported Nucleoli Renal cancer:4.98e-4 (favourable), Urothelial cancer:6.90e-4 (favourable) Expressed in all Expressed in all thyroid gland: 40.5 Expressed in all +SLC47A2 FLJ31196, MATE2, MATE2-K ENSG00000180638 Solute carrier family 47 member 2 17 19678288-19718979 Predicted membrane proteins, Transporters Evidence at protein level Glioma:7.41e-4 (unfavourable) Tissue enhanced Group enriched 5 fallopian tube: 16.5;kidney: 49.3 epididymis: 6.4 Cell line enhanced hTCEpi: 1.5 +PRF1 HPLH2, P1, PFP ENSG00000180644 Perforin 1 10 70597348-70602775 Cancer-related genes, Disease related genes, Potential drug targets, Predicted secreted proteins, Transporters Evidence at protein level CAB002436, HPA037940 Approved Approved Cytosol Renal cancer:1.08e-5 (unfavourable), Endometrial cancer:2.09e-4 (favourable), Head and neck cancer:3.54e-4 (favourable) Expressed in all Tissue enhanced spleen: 52.8 lymph node: 20.8 Cell line enriched 16 HDLM-2: 221.2 +OR2A4 OR2A10 ENSG00000180658 Olfactory receptor family 2 subfamily A member 4 6 131700469-131701401 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA058272 Uncertain Tissue enriched Not detected testis: 0.2 Not detected +MAB21L1 CAGR1 ENSG00000180660 Mab-21 like 1 13 35474182-35477209 Predicted intracellular proteins Evidence at protein level HPA049324, HPA059864 Enhanced Nucleus
Cytosol Mixed Tissue enhanced adrenal gland: 5.5;breast: 5.2 adipose tissue: 2.4 Cell line enhanced BJ: 29.7;BJ hTERT+ SV40 Large T+: 36.9;HBF TERT88: 41.4;SH-SY5Y: 135.2 +YOD1 DKFZp451J1719, DUBA8, OTUD2 ENSG00000180667 YOD1 deubiquitinase 1 207043849-207052980 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028400, HPA028439 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Tissue enhanced bone marrow: 37.1 esophagus: 27.8 Cell line enhanced HEL: 78.5;K-562: 55.5 +TMEM64 DKFZp762C1112 ENSG00000180694 Transmembrane protein 64 8 90621995-90791632 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level CAB034221 Uncertain Expressed in all Expressed in all epididymis: 176.0 Mixed +C3orf22 MGC34728 ENSG00000180697 Chromosome 3 open reading frame 22 3 126526999-126558965 Predicted intracellular proteins Evidence at protein level HPA059199 Enhanced Not detected Tissue enriched 326 testis: 32.6 all non-specific tissues: 0.0 Not detected +OR10K2 ENSG00000180708 Olfactory receptor family 10 subfamily K member 2 1 158419928-158420866 G-protein coupled receptors, Predicted membrane proteins No evidence HPA059125 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +CHRM4 ENSG00000180720 Cholinergic receptor muscarinic 4 11 46385098-46386608 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB022444, HPA072083 Uncertain Uncertain Nucleus
Golgi apparatus Mixed Tissue enhanced cerebral cortex: 8.1;small intestine: 7.8;spleen: 21.4 testis: 6.9 Cell line enhanced RH-30: 3.3;SCLC-21H: 11.7;U-2 OS: 3.0 +SHISA2 bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166 ENSG00000180730 Shisa family member 2 13 26044597-26051031 Predicted membrane proteins Evidence at protein level HPA049752, HPA050172 Uncertain Approved Nucleoplasm
Nuclear bodies
Vesicles Renal cancer:2.43e-4 (favourable), Lung cancer:3.30e-4 (favourable) Mixed Tissue enhanced breast: 22.3;thyroid gland: 48.3 epididymis: 13.1 Cell line enhanced LHCN-M2: 21.2;NTERA-2: 18.4;RH-30: 56.6;U-2197: 34.1 +S1PR5 Edg-8, EDG8 ENSG00000180739 Sphingosine-1-phosphate receptor 5 19 10512742-10517931 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029683 Enhanced Renal cancer:6.71e-7 (unfavourable) Group enriched Tissue enhanced cerebral cortex: 14.9;skin: 22.1 spleen: 12.0 Cell line enhanced HaCaT: 25.0;RT4: 14.8;T-47d: 10.9;U-2 OS: 10.7 +CLRN3 MGC32871, TMEM12, USH3AL1 ENSG00000180745 Clarin 3 10 127877841-127892947 Predicted membrane proteins, Transporters Evidence at protein level HPA014482 Approved Stomach cancer:8.98e-4 (favourable) Group enriched Group enriched 8 colon: 69.9;duodenum: 73.3;gallbladder: 23.6;kidney: 44.3;liver: 40.4;rectum: 76.3;small intestine: 97.5 appendix: 7.2 Cell line enriched 6 CACO-2: 1.9 +GPR157 FLJ12132 ENSG00000180758 G protein-coupled receptor 157 1 9100305-9129170 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA028697 Uncertain Uncertain Nucleoli
Plasma membrane
Cell Junctions Expressed in all Mixed parathyroid gland: 24.2 Cell line enhanced SK-BR-3: 46.8 +CHST13 C4ST3 ENSG00000180767 Carbohydrate sulfotransferase 13 3 126524283-126543291 Enzymes, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced liver: 5.9;testis: 6.3 spleen: 2.9 Group enriched 6 CACO-2: 13.9;Hep G2: 20.6;NB-4: 12.8;THP-1: 7.9 +AGTR2 AT2, MRX88 ENSG00000180772 Angiotensin II receptor type 2 X 116170722-116174972 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Group enriched Group enriched 6 cervix, uterine: 6.8;endometrium: 13.9;fallopian tube: 3.8;lung: 12.6;smooth muscle: 17.6 adrenal gland: 1.9 Not detected +SLC36A4 FLJ38932, PAT4 ENSG00000180773 Solute carrier family 36 member 4 11 93144171-93197964 Predicted membrane proteins, Transporters Evidence at protein level HPA017887 Enhanced Approved Golgi apparatus
Plasma membrane
Cytosol Expressed in all Mixed thyroid gland: 14.8 Mixed +ZDHHC20 FLJ25952 ENSG00000180776 Zinc finger DHHC-type containing 20 13 21372573-21459370 Enzymes, Predicted membrane proteins Evidence at protein level HPA014483, HPA014702 Approved Uncertain Vesicles
Plasma membrane
Mitochondria Renal cancer:1.01e-4 (unfavourable), Pancreatic cancer:6.55e-4 (unfavourable) Expressed in all Expressed in all testis: 60.5 Expressed in all +ANKRD30B NY-BR-1.1 ENSG00000180777 Ankyrin repeat domain 30B 18 14728272-14852738 Predicted intracellular proteins Evidence at protein level HPA060455, HPA071849 Uncertain Uncertain Nucleoli Tissue enhanced Tissue enriched 11 testis: 14.4 breast: 1.3 Cell line enriched 8 U-2197: 41.6 +OR51E1 GPR136, GPR164, OR51E1P, OR52A3P ENSG00000180785 Olfactory receptor family 51 subfamily E member 1 11 4643420-4655488 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level CAB019995, HPA051439 Approved Renal cancer:1.23e-6 (unfavourable) Tissue enriched Tissue enhanced adipose tissue: 6.4;placenta: 9.6;prostate: 9.0 smooth muscle,urinary bladder: 1.7 Cell line enriched 96 SCLC-21H: 10.5 +ZFP3 FLJ30726, ZNF752 ENSG00000180787 ZFP3 zinc finger protein 17 5078248-5096374 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053085, HPA057290 Approved Approved Nucleoplasm
Cytosol Renal cancer:7.69e-7 (favourable), Pancreatic cancer:1.07e-4 (favourable), Lung cancer:1.38e-4 (favourable), Cervical cancer:5.68e-4 (favourable) Mixed Mixed parathyroid gland: 13.1 Cell line enhanced SH-SY5Y: 6.1 +ARSJ FLJ23548 ENSG00000180801 Arylsulfatase family member J 4 113900284-113979727 Predicted intracellular proteins Evidence at protein level HPA036481, HPA036482 Uncertain Supported Nucleoli
Actin filaments Renal cancer:2.97e-6 (favourable), Head and neck cancer:6.08e-4 (unfavourable) Mixed Mixed parathyroid gland: 12.7 Mixed +HOXC9 HOX3, HOX3B ENSG00000180806 Homeobox C9 12 53994895-54003337 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063965, HPA072160 Enhanced Nucleoplasm Mixed Tissue enhanced skeletal muscle: 6.2 adipose tissue: 3.3 Cell line enhanced AN3-CA: 19.7;HDLM-2: 26.0;HEK 293: 30.3 +MAP3K15 ASK3, bA723P2.3, FLJ16518 ENSG00000180815 Mitogen-activated protein kinase kinase kinase 15 X 19360056-19515261 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004006 Approved Vesicles Mixed Tissue enriched 6 adrenal gland: 14.3 spleen: 2.2 Cell line enhanced A549: 1.8;HAP1: 5.1;HEK 293: 3.8;REH: 2.4 +PPA1 IOPPP, PP, PP1, Ppase, SID6-8061 ENSG00000180817 Pyrophosphatase (inorganic) 1 10 70202830-70233911 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019878, HPA020096 Supported Supported Vesicles Expressed in all Expressed in all breast: 226.6 Expressed in all +HOXC10 HOX3I ENSG00000180818 Homeobox C10 12 53985065-53990279 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053919 Uncertain Supported Nucleoplasm
Nuclear bodies Mixed Group enriched 9 kidney: 18.9;skeletal muscle: 40.3;skin: 8.4 breast: 2.5 Cell line enhanced AN3-CA: 275.9;T-47d: 95.2 +PSMG4 C6orf86, PAC4 ENSG00000180822 Proteasome assembly chaperone 4 6 3231403-3303373 Predicted intracellular proteins Evidence at protein level HPA067652 Approved Nucleus
Mitochondria Renal cancer:7.45e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 22.2 Expressed in all +BHLHE22 Beta3, BHLHB5, bHLHe22, CAGL85, TNRC20 ENSG00000180828 Basic helix-loop-helix family member e22 8 64580367-64583628 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA064128, HPA064872, HPA067500 Enhanced Mixed Tissue enhanced cerebral cortex: 12.2 seminal vesicle: 3.3 Cell line enriched 15 THP-1: 52.6 +MAP6D1 FLJ12748, SL21 ENSG00000180834 MAP6 domain containing 1 3 183815876-183825594 Predicted intracellular proteins Evidence at protein level HPA037991 Supported Approved Cytosol Prostate cancer:3.37e-4 (unfavourable) Mixed Group enriched 7 cerebral cortex: 39.7;skeletal muscle: 10.3 skin: 3.6 Cell line enhanced T-47d: 66.1 +ZNF443 ZK1 ENSG00000180855 Zinc finger protein 443 19 12429707-12441112 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003150, HPA018683 Supported Uncertain Nucleoplasm
Microtubule organizing center Renal cancer:2.74e-7 (favourable), Urothelial cancer:3.91e-4 (favourable) Expressed in all Mixed parathyroid gland: 7.0 Mixed +CXCR2 CD182, CMKAR2, IL8RB ENSG00000180871 C-X-C motif chemokine receptor 2 2 218125289-218137253 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB016268, HPA031999, HPA032017 Enhanced Mixed Tissue enhanced appendix: 55.7;spleen: 36.7 esophagus: 29.9 Group enriched 10 BEWO: 13.6;HL-60: 6.5;HMC-1: 14.3;THP-1: 10.4;U-937: 11.8 +DEFB112 DEFB-12 ENSG00000180872 Defensin beta 112 6 50043575-50048651 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 53 epididymis: 172.5 seminal vesicle: 3.2 Not detected +GREM2 CKTSF1B2, DAND3, FLJ21195, Prdc ENSG00000180875 Gremlin 2, DAN family BMP antagonist 1 240489573-240612149 Disease related genes, Predicted secreted proteins Evidence at protein level CAB009920 Uncertain Mixed Tissue enhanced gallbladder: 48.8;parathyroid gland: 78.3 rectum: 22.6 Cell line enhanced BJ: 5.1;BJ hTERT+: 5.2;fHDF/TERT166: 25.0 +C11orf42 MGC34805 ENSG00000180878 Chromosome 11 open reading frame 42 11 6205566-6211132 Predicted intracellular proteins Evidence at protein level HPA063404 Enhanced Not detected Tissue enriched 11 testis: 20.3 skin: 1.8 Cell line enhanced HEK 293: 1.2;HeLa: 1.0 +SSR4 TRAPD ENSG00000180879 Signal sequence receptor subunit 4 X 153793516-153798505 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA045209 Enhanced Renal cancer:5.51e-6 (unfavourable), Endometrial cancer:1.76e-4 (favourable) Expressed in all Expressed in all epididymis: 979.6 Expressed in all +CAPS2 ENSG00000180881 Calcyphosine 2 12 75275979-75390928 Predicted intracellular proteins Evidence at transcript level HPA040004 Uncertain Approved Nucleus
Nucleoli
Centrosome Mixed Tissue enhanced fallopian tube: 15.9 testis: 6.9 Mixed +ZNF792 FLJ38451 ENSG00000180884 Zinc finger protein 792 19 34956354-34964049 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035157, HPA035158 Supported Approved Nucleoplasm
Nuclear bodies Colorectal cancer:2.72e-4 (favourable) Expressed in all Mixed lung: 6.2 Cell line enhanced HEL: 11.5;HMC-1: 14.3;SH-SY5Y: 11.1 +CUEDC1 ENSG00000180891 CUE domain containing 1 17 57861243-57955323 Predicted intracellular proteins Evidence at protein level HPA023050, HPA024836 Approved Uncertain Centrosome
Mitochondria
Cytosol Liver cancer:2.65e-5 (unfavourable), Renal cancer:8.46e-4 (favourable) Expressed in all Expressed in all fallopian tube: 52.4 Mixed +SCRIB KIAA0147, SCRB1, Vartul ENSG00000180900 Scribbled planar cell polarity protein 8 143790920-143815379 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015463, CAB022081, HPA023557, HPA064312 Enhanced Enhanced Nucleoplasm
Plasma membrane
Cell Junctions
Rods & Rings Expressed in all Expressed in all skin: 22.0 Expressed in all +KCTD2 KIAA0176 ENSG00000180901 Potassium channel tetramerization domain containing 2 17 75032575-75065889 Predicted intracellular proteins Evidence at protein level Pancreatic cancer:1.25e-5 (favourable), Liver cancer:1.83e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 3.4;cerebral cortex: 7.3 kidney: 2.0 Cell line enhanced HEK 293: 10.4 +D2HGDH D2HGD, FLJ42195, MGC25181 ENSG00000180902 D-2-hydroxyglutarate dehydrogenase 2 241734579-241768816 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA056216, HPA060548 Uncertain Approved Mitochondria Head and neck cancer:9.11e-4 (favourable) Expressed in all Expressed in all skin: 46.5 Expressed in all +OXTR ENSG00000180914 Oxytocin receptor 3 8750408-8769628 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Mixed Tissue enriched 13 breast: 65.4 fallopian tube: 4.9 Cell line enhanced BJ: 357.1;BJ hTERT+: 104.6;BJ hTERT+ SV40 Large T+: 111.8;fHDF/TERT166: 330.6 +CMTR2 AFT, FLJ11171, FTSJD1, MTr2 ENSG00000180917 Cap methyltransferase 2 16 71281389-71289715 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041700, HPA048265 Uncertain Approved Nuclear speckles
Cell Junctions Renal cancer:4.97e-5 (favourable) Expressed in all Expressed in all testis: 18.9 Expressed in all +OR56B4 ENSG00000180919 Olfactory receptor family 56 subfamily B member 4 11 6107684-6108835 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected appendix,spleen,thyroid gland: 0.1 Not detected +FAM83H FLJ46072 ENSG00000180921 Family with sequence similarity 83 member H 8 143723933-143733801 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024505, HPA024604 Enhanced Approved Cytosol Lung cancer:3.77e-4 (unfavourable), Stomach cancer:4.42e-4 (favourable) Expressed in all Tissue enhanced skin: 17.2 esophagus: 10.3 Cell line enhanced HaCaT: 37.2;MCF7: 45.2 +GPR62 ENSG00000180929 G protein-coupled receptor 62 3 51955314-51957504 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enriched 14 cerebral cortex: 8.0 ovary: 0.5 Cell line enriched 6 SCLC-21H: 2.2 +OR56A1 ENSG00000180934 Olfactory receptor family 56 subfamily A member 1 11 6026671-6027741 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.4 Not detected +ZNF572 FLJ38002 ENSG00000180938 Zinc finger protein 572 8 124973298-124979389 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA066838 Enhanced Approved Nuclear speckles Expressed in all Mixed testis: 6.7 Mixed +ST20 HCCS-1 ENSG00000180953 Suppressor of tumorigenicity 20 15 79898840-79923702 Predicted intracellular proteins Evidence at transcript level Renal cancer:7.69e-8 (unfavourable) Expressed in all Mixed spleen: 11.3 Mixed +PITPNB VIB1B ENSG00000180957 Phosphatidylinositol transfer protein beta 22 27851669-27920134 Predicted intracellular proteins Evidence at protein level HPA000528 Uncertain Approved Vesicles
Cytosol Head and neck cancer:5.28e-4 (unfavourable) Expressed in all Expressed in all placenta: 70.3 Expressed in all +TCEAL8 MGC45400, WEX3 ENSG00000180964 Transcription elongation factor A like 8 X 103252995-103255203 Predicted intracellular proteins Evidence at protein level HPA059115 Uncertain Approved Nucleoplasm Head and neck cancer:8.53e-6 (unfavourable) Expressed in all Expressed in all epididymis: 149.7 Mixed +OR52E4 ENSG00000180974 Olfactory receptor family 52 subfamily E member 4 11 5884271-5885300 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.2 Not detected +LRRC57 FLJ36812 ENSG00000180979 Leucine rich repeat containing 57 15 42537820-42548802 Predicted intracellular proteins Evidence at protein level HPA040894 Approved Approved Mitochondria
Cytosol Renal cancer:2.15e-4 (favourable) Expressed in all Expressed in all bone marrow: 14.9 Expressed in all +OR52N2 ENSG00000180988 Olfactory receptor family 52 subfamily N member 2 11 5820314-5821348 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.8 Not detected +MRPL14 MRP-L32, RPML32 ENSG00000180992 Mitochondrial ribosomal protein L14 6 44113454-44127457 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA038769, HPA076790 Uncertain Supported Mitochondria Renal cancer:7.46e-5 (unfavourable), Thyroid cancer:1.08e-4 (favourable), Ovarian cancer:4.81e-4 (favourable) Expressed in all Expressed in all lung: 85.6 Expressed in all +GPR137C DKFZp762F0713, TM7SF1L2 ENSG00000180998 G protein-coupled receptor 137C 14 52553148-52637713 Predicted membrane proteins Evidence at transcript level HPA003640, HPA030763 Uncertain Approved Vesicles Mixed Group enriched 6 cerebral cortex: 18.0;epididymis: 10.8;testis: 6.8 gallbladder: 2.1 Mixed +C1orf105 ENSG00000180999 Chromosome 1 open reading frame 105 1 172420688-172468831 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 7 testis: 46.2 epididymis: 6.6 Cell line enriched 12 BEWO: 26.1 +OR52N1 ENSG00000181001 Olfactory receptor family 52 subfamily N member 1 11 5787854-5788816 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins No evidence HPA054028 Uncertain Not detected Not detected adipose tissue: 0.1 Not detected +BBS12 C4orf24, FLJ35630, FLJ41559 ENSG00000181004 Bardet-Biedl syndrome 12 4 122732702-122744943 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA061856 Approved Renal cancer:9.89e-6 (favourable), Endometrial cancer:5.69e-4 (favourable) Mixed Mixed thyroid gland: 16.0 Mixed +ZFP82 KIAA1948, MGC45380, ZNF545 ENSG00000181007 ZFP82 zinc finger protein 19 36383120-36418656 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA051669, HPA060470 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Mixed Mixed thyroid gland: 8.8 Mixed +OR52N5 OR52N5Q ENSG00000181009 Olfactory receptor family 52 subfamily N member 5 11 5777634-5778667 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected adipose tissue: 0.1 Not detected +C17orf47 FLJ40121 ENSG00000181013 Chromosome 17 open reading frame 47 17 58541587-58544368 Predicted intracellular proteins Evidence at protein level HPA028424 Uncertain Not detected Tissue enriched 32 testis: 16.3 spleen: 0.5 Not detected +LSMEM1 C7orf53, FLJ39575 ENSG00000181016 Leucine rich single-pass membrane protein 1 7 112480853-112491062 Predicted membrane proteins Evidence at protein level HPA013753, HPA047988 Uncertain Supported Cytosol Mixed Tissue enriched 11 skeletal muscle: 31.8 testis: 2.8 Cell line enhanced HeLa: 4.9 +NQO1 DHQU, DIA4, DTD, NMOR1, QR1 ENSG00000181019 NAD(P)H quinone dehydrogenase 1 16 69706996-69726951 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA007308, CAB012421 Enhanced Enhanced Cytosol Head and neck cancer:1.45e-4 (unfavourable) Expressed in all Tissue enhanced breast: 379.3;stomach: 556.0 gallbladder: 320.2 Expressed in all +OR56B1 OR56B1P ENSG00000181023 Olfactory receptor family 56 subfamily B member 1 11 5736517-5737491 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA045043 Uncertain Not detected Not detected parathyroid gland: 0.3 Not detected +AEN FLJ12484, FLJ12562, ISG20L1 ENSG00000181026 Apoptosis enhancing nuclease 15 88621296-88632282 Predicted intracellular proteins Evidence at protein level HPA048599 Supported Nucleus
Nuclear membrane
Nucleoli Endometrial cancer:1.72e-4 (favourable) Expressed in all Mixed gallbladder: 19.8 Expressed in all +FKRP LGMD2I, MDC1C ENSG00000181027 Fukutin related protein 19 46746046-46776988 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043115, HPA060454 Approved Approved Nucleus
Golgi apparatus
Cytosol Pancreatic cancer:8.98e-4 (favourable) Expressed in all Expressed in all placenta: 14.9 Expressed in all +TRAPPC5 MGC52424, TRS31 ENSG00000181029 Trafficking protein particle complex 5 19 7680843-7687703 Predicted intracellular proteins Evidence at protein level HPA042221, HPA049064 Uncertain Approved Vesicles Mixed Expressed in all testis: 69.8 Expressed in all +RPH3AL Noc2 ENSG00000181031 Rabphilin 3A-like (without C2 domains) 17 212389-386254 Predicted intracellular proteins Evidence at protein level HPA024311 Approved Renal cancer:1.03e-8 (favourable) Mixed Mixed spleen: 11.8 Cell line enhanced A549: 19.6 +SLC25A42 MGC26694 ENSG00000181035 Solute carrier family 25 member 42 19 19063999-19112888 Predicted membrane proteins, Transporters Evidence at protein level HPA049449 Approved Supported Mitochondria Lung cancer:4.11e-4 (favourable), Cervical cancer:5.04e-4 (favourable) Expressed in all Expressed in all kidney: 28.8 Mixed +FCRL6 FcRH6, FLJ16056, IFGP6 ENSG00000181036 Fc receptor like 6 1 159800511-159816251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced spleen: 18.4 lung: 8.9 Not detected +METTL23 C17orf95, LOC124512 ENSG00000181038 Methyltransferase like 23 17 76726830-76733936 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:3.93e-7 (unfavourable), Liver cancer:4.18e-6 (unfavourable) Expressed in all Expressed in all testis: 86.1 Expressed in all +SLC26A11 ENSG00000181045 Solute carrier family 26 member 11 17 80219699-80253500 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA029893 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Liver cancer:1.82e-6 (unfavourable), Pancreatic cancer:1.43e-5 (favourable), Endometrial cancer:1.55e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 34.4 Mixed +HIGD1A DKFZP564K247, HIG1, RCF1A ENSG00000181061 HIG1 hypoxia inducible domain family member 1A 3 42784298-42804531 Predicted membrane proteins Evidence at protein level HPA043336 Approved Supported Nucleoplasm
Mitochondria Renal cancer:3.99e-8 (favourable), Colorectal cancer:2.12e-4 (favourable) Expressed in all Expressed in all rectum: 328.9 Expressed in all +CHRM2 ENSG00000181072 Cholinergic receptor muscarinic 2 7 136868669-137020255 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB022338, HPA029795 Approved Tissue enhanced Tissue enhanced gallbladder: 18.3;heart muscle: 25.8;smooth muscle: 13.7 urinary bladder: 5.9 Cell line enhanced BJ: 14.1;BJ hTERT+: 15.2;fHDF/TERT166: 71.3;HHSteC: 10.8 +OR52N4 ENSG00000181074 Olfactory receptor family 52 subfamily N member 4 (gene/pseudogene) 11 5754693-5755729 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Mixed spleen: 2.4 Not detected +MAPK15 ERK7, ERK8 ENSG00000181085 Mitogen-activated protein kinase 15 8 143716259-143722458 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002704 Approved Nucleoplasm
Cell Junctions
Cytosol Mixed Tissue enhanced fallopian tube: 43.7 parathyroid gland: 13.2 Cell line enhanced CAPAN-2: 6.9;HeLa: 10.4;MCF7: 11.8;T-47d: 12.5 +EHMT1 bA188C12.1, Eu-HMTase1, FLJ12879, KIAA1876, KMT1D ENSG00000181090 Euchromatic histone lysine methyltransferase 1 9 137618963-137870016 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA060022 Supported Nucleoplasm
Nuclear bodies Endometrial cancer:6.56e-4 (favourable), Head and neck cancer:8.91e-4 (favourable) Expressed in all Expressed in all testis: 65.0 Expressed in all +ADIPOQ ACDC, ACRP30, adiponectin, AdipoQ, apM1, GBP28 ENSG00000181092 Adiponectin, C1Q and collagen domain containing 3 186842690-186858463 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB046467, HPA051767 Uncertain Group enriched Tissue enriched 17 adipose tissue: 937.7 breast: 56.0 Cell line enriched 475 ASC diff: 213.8 +F2R CF2R, PAR-1, PAR1, TR ENSG00000181104 Coagulation factor II thrombin receptor 5 76716043-76735781 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB008973, CAB012962 Approved Renal cancer:2.21e-7 (unfavourable) Expressed in all Expressed in all spleen: 94.1 Cell line enhanced HUVEC TERT2: 297.4;WM-115: 331.7 +ZNF707 ENSG00000181135 Zinc finger protein 707 8 143684452-143713898 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044991 Approved Enhanced Nucleoplasm Endometrial cancer:6.79e-4 (unfavourable) Expressed in all Mixed skin: 4.9 Mixed +MUC16 CA125, FLJ14303 ENSG00000181143 Mucin 16, cell surface associated 19 8848844-8981342 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB055172, HPA065600 Enhanced Tissue enhanced Tissue enhanced cervix, uterine: 24.0;fallopian tube: 9.4 endometrium: 3.5 Cell line enhanced A-431: 20.2;CAPAN-2: 7.0;HaCaT: 6.8;HeLa: 26.2 +NPM1 B23, NPM ENSG00000181163 Nucleophosmin 5 171387116-171411137 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA011384, CAB012983 Supported Enhanced Nucleus
Nucleoli Renal cancer:2.89e-6 (unfavourable), Liver cancer:4.82e-6 (unfavourable), Head and neck cancer:7.48e-4 (unfavourable) Expressed in all Expressed in all ovary: 1800.2 Expressed in all +PJA1 FLJ11830, RNF70 ENSG00000181191 Praja ring finger ubiquitin ligase 1 X 69160851-69165793 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000595 Enhanced Approved Nucleus
Nucleoli Renal cancer:7.44e-5 (favourable) Expressed in all Expressed in all epididymis: 181.5 Cell line enhanced HAP1: 88.6 +DHTKD1 CMT2Q, DKFZP762M115, KIAA1630, MGC3090 ENSG00000181192 Dehydrogenase E1 and transketolase domain containing 1 10 12068972-12123225 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037949, HPA037950, HPA066098 Approved Supported Mitochondria Renal cancer:3.43e-4 (favourable) Expressed in all Expressed in all liver: 66.5 Expressed in all +PENK ENSG00000181195 Proenkephalin 8 56436674-56446734 Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA013138, CAB016390 Enhanced Tissue enhanced Group enriched 9 adrenal gland: 566.0;testis: 208.0 prostate: 41.3 Cell line enhanced ASC diff: 10.8;ASC TERT1: 6.5;BJ: 7.7;THP-1: 5.8 +C4orf50 FLJ46481 ENSG00000181215 Chromosome 4 open reading frame 50 4 5897373-6018507 Predicted intracellular proteins Evidence at transcript level HPA058292 Uncertain Not detected Not detected cerebral cortex: 0.9 Not detected +HIST3H2A MGC3165 ENSG00000181218 Histone cluster 3 H2A 1 228456979-228457873 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041189 Supported Glioma:5.44e-4 (favourable) Expressed in all Tissue enhanced adrenal gland: 22.7 cerebral cortex: 10.6 Cell line enhanced SCLC-21H: 58.3 +ZNF746 FLJ31413, PARIS ENSG00000181220 Zinc finger protein 746 7 149472794-149497817 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020272 Approved Renal cancer:7.47e-6 (unfavourable), Liver cancer:2.32e-5 (unfavourable), Pancreatic cancer:4.22e-4 (favourable) Expressed in all Expressed in all testis: 23.0 Expressed in all +POLR2A POLR2, POLRA, RPB1 ENSG00000181222 RNA polymerase II subunit A 17 7484366-7514616 Enzymes, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level CAB012226, CAB016388, HPA021563, CAB022311, HPA053012 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all testis: 117.6 Expressed in all +TMEM132C DKFZp761O2018, PPP1R152 ENSG00000181234 Transmembrane protein 132C 12 128267403-128707915 Predicted membrane proteins Evidence at protein level HPA015633, HPA015984 Supported Centrosome
Cytosol Tissue enhanced Tissue enhanced adipose tissue: 34.8;cervix, uterine: 24.1 fallopian tube: 15.9 Group enriched 5 AF22: 3.7;ASC diff: 3.5;Daudi: 4.4 +SLC25A41 APC4, FLJ40442, MGC34725 ENSG00000181240 Solute carrier family 25 member 41 19 6426037-6433779 Predicted intracellular proteins, Transporters Evidence at transcript level HPA043591 Uncertain Not detected Tissue enhanced cerebral cortex: 1.0;testis: 1.9 esophagus: 0.4 Cell line enhanced HMC-1: 2.4;U-937: 1.3 +TMEM136 MGC17839 ENSG00000181264 Transmembrane protein 136 11 120325129-120333682 Predicted membrane proteins Evidence at transcript level HPA074432 Approved Vesicles
Cytosol Endometrial cancer:6.65e-4 (unfavourable) Expressed in all Mixed adrenal gland: 12.6 Mixed +OR5AK2 ENSG00000181273 Olfactory receptor family 5 subfamily AK member 2 11 56988872-56989867 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 68 spleen: 7.2 lung: 0.1 Not detected +FRAT2 ENSG00000181274 FRAT2, WNT signaling pathway regulator 10 97332497-97334709 Predicted intracellular proteins Evidence at transcript level HPA049763 Uncertain Approved Nucleus
Mitochondria Renal cancer:2.55e-4 (favourable), Liver cancer:3.02e-4 (unfavourable) Expressed in all Expressed in all duodenum: 25.5 Mixed +TMEM102 CBAP, FLJ36878 ENSG00000181284 Transmembrane protein 102 17 7435443-7437679 Predicted intracellular proteins Evidence at protein level HPA024433 Uncertain Approved Vesicles Renal cancer:9.90e-4 (favourable) Expressed in all Mixed adrenal gland: 3.5 Mixed +TMEM132E DFNB99 ENSG00000181291 Transmembrane protein 132E 17 34580749-34639318 Disease related genes, Predicted membrane proteins Evidence at protein level HPA070608 Approved Renal cancer:1.55e-4 (unfavourable) Group enriched Group enriched 5 cerebral cortex: 4.8;duodenum: 1.7;kidney: 3.2;small intestine: 1.0;testis: 1.5 cervix, uterine: 0.4 Cell line enriched 7 RPMI-8226: 31.6 +ZNF322 bA457M11.2, bA457M11.3, HCG12, ZNF322A, ZNF388, ZNF489 ENSG00000181315 Zinc finger protein 322 6 26634383-26659752 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043161, HPA046692 Approved Supported Nucleus
Centrosome
Cytosol Glioma:1.75e-4 (favourable), Lung cancer:8.57e-4 (favourable) Expressed in all Mixed parathyroid gland: 29.2 Mixed +NME9 NM23-H9, TXL-2, TXNDC6 ENSG00000181322 NME/NM23 family member 9 3 138261437-138329886 Predicted intracellular proteins Evidence at protein level HPA040000, HPA043881 Enhanced Mixed Tissue enhanced fallopian tube: 30.0 testis: 6.7 Mixed +SPEM1 C17orf83, FLJ40081 ENSG00000181323 Spermatid maturation 1 17 7420360-7421632 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 321 testis: 32.0 all non-specific tissues: 0.0 Not detected +HEPHL1 DKFZp686F22190 ENSG00000181333 Hephaestin like 1 11 94021361-94113751 Predicted membrane proteins Evidence at protein level HPA031517 Uncertain Cervical cancer:4.94e-4 (unfavourable) Tissue enriched Group enriched 11 esophagus: 3.2;tonsil: 9.4 testis: 0.5 Cell line enhanced HaCaT: 1.4;HBEC3-KT: 2.0 +LRRC75A C17orf76, FAM211A, FLJ35696 ENSG00000181350 Leucine rich repeat containing 75A 17 16441577-16492153 Predicted intracellular proteins Evidence at protein level HPA028528 Uncertain Pancreatic cancer:7.46e-5 (favourable) Mixed Tissue enhanced duodenum: 11.0 small intestine: 11.0 Cell line enhanced HEL: 6.2 +OFCC1 MRDS1 ENSG00000181355 Orofacial cleft 1 candidate 1 6 9596110-10211608 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035725, HPA050619 Uncertain Approved Nucleoplasm Not detected Tissue enhanced testis: 2.8 cervix, uterine,duodenum,placenta: 0.7 Cell line enhanced CACO-2: 2.5;K-562: 4.4;SK-MEL-30: 2.7 +OR5M8 ENSG00000181371 Olfactory receptor family 5 subfamily M member 8 11 56490435-56491370 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.1 Not detected +CCL13 CKb10, MCP-4, MGC17134, NCC-1, SCYA13, SCYL1 ENSG00000181374 C-C motif chemokine ligand 13 17 34356452-34358610 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Mixed lung: 31.6 Cell line enhanced ASC diff: 1.2;BJ hTERT+: 1.3;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;HMC-1: 1.1;HSkMC: 1.1 +CFAP65 CCDC108, DKFZp434O0527, MGC35338 ENSG00000181378 Cilia and flagella associated protein 65 2 219002846-219041527 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA055156 Uncertain Endometrial cancer:6.08e-5 (favourable) Tissue enhanced Group enriched 7 fallopian tube: 41.2;testis: 17.7 lung: 3.9 Cell line enhanced SH-SY5Y: 1.0 +DDX60L FLJ31033 ENSG00000181381 DEAD-box helicase 60-like 4 168356735-168537786 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043211, HPA055501 Approved Approved Plasma membrane
Cytosol Pancreatic cancer:3.04e-5 (unfavourable), Renal cancer:2.94e-4 (unfavourable) Expressed in all Mixed bone marrow: 33.7 Mixed +SYNE4 C19orf46, DFNB76, FLJ36445, Nesp4, Nesprin-4 ENSG00000181392 Spectrin repeat containing nuclear envelope family member 4 19 36003307-36008793 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060253 Uncertain Renal cancer:8.64e-9 (favourable) Mixed Tissue enhanced parathyroid gland: 18.7 prostate: 11.8 Cell line enhanced CACO-2: 27.6;Hep G2: 20.0;MCF7: 26.0;SK-BR-3: 30.3;T-47d: 29.1 +OGFOD3 C17orf101, FLJ22222 ENSG00000181396 2-oxoglutarate and iron dependent oxygenase domain containing 3 17 82389223-82418637 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052099 Uncertain Approved Nucleoplasm Renal cancer:5.72e-4 (favourable) Expressed in all Expressed in all thyroid gland: 26.4 Expressed in all +WASHC1 FAM39E, FLJ00038, WASH1 ENSG00000181404 WASH complex subunit 1 9 14521-29739 Predicted intracellular proteins Evidence at protein level HPA002689 Uncertain Supported Vesicles Expressed in all Expressed in all epididymis: 24.5 Expressed in all +UTS2R GPR14 ENSG00000181408 Urotensin 2 receptor 17 82374230-82375586 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Group enriched Tissue enhanced testis: 1.1;thyroid gland: 1.3 duodenum: 0.3 Cell line enhanced Karpas-707: 5.1;SCLC-21H: 2.4;U-266/70: 13.2 +AATK AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77 ENSG00000181409 Apoptosis associated tyrosine kinase 17 81117295-81166077 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009073 Enhanced Uncertain Mitochondria Mixed Tissue enhanced cerebral cortex: 36.4;duodenum: 23.4 small intestine: 18.3 Group enriched 5 CACO-2: 35.4;SH-SY5Y: 15.1 +DDN KIAA0749 ENSG00000181418 Dendrin 12 48995149-48999309 Predicted intracellular proteins Evidence at protein level HPA060952 Uncertain Approved Nucleoplasm
Cytosol Mixed Group enriched 10 cerebral cortex: 96.0;skeletal muscle: 46.6 kidney: 6.9 Cell line enhanced HAP1: 12.6;RPMI-8226: 16.5;SCLC-21H: 14.1 +SAGE1 CT14, SAGE ENSG00000181433 Sarcoma antigen 1 X 135889205-135913061 Predicted intracellular proteins Evidence at protein level HPA003033, HPA003208 Enhanced Enhanced Nucleus Mixed Tissue enriched 58 testis: 8.9 cerebral cortex: 0.1 Group enriched 11 AN3-CA: 19.0;K-562: 13.8;Karpas-707: 18.3;U-2 OS: 7.4;U-266/70: 6.7;U-266/84: 16.5 +ZNF467 EZI, Zfp467 ENSG00000181444 Zinc finger protein 467 7 149764182-149773479 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042907 Uncertain Approved Mitochondria Pancreatic cancer:4.56e-4 (favourable) Expressed in all Mixed spleen: 14.1 Cell line enhanced AN3-CA: 30.3;HMC-1: 16.5;T-47d: 17.2 +SOX2 ENSG00000181449 SRY-box 2 3 181711924-181714436 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB010648, HPA045725, HPA071379 Approved Supported Supported Nucleoplasm Tissue enhanced Tissue enriched 8 cerebral cortex: 117.9 esophagus: 14.8 Cell line enhanced AF22: 273.3;HAP1: 122.7;NTERA-2: 226.0 +ZNF678 MGC42493 ENSG00000181450 Zinc finger protein 678 1 227563543-227677443 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA028507 Uncertain Approved Nucleoli
Mitochondria
Cytosol Expressed in all Mixed thyroid gland: 8.9 Expressed in all +TMEM45A DERP7, FLJ10134 ENSG00000181458 Transmembrane protein 45A 3 100492619-100577444 Predicted membrane proteins Evidence at protein level HPA062101 Uncertain Approved Endoplasmic reticulum
Vesicles Renal cancer:6.18e-11 (unfavourable), Lung cancer:7.42e-4 (unfavourable) Expressed in all Tissue enriched 10 skin: 563.0 placenta: 58.7 Cell line enhanced ASC diff: 279.1 +RAP2B ENSG00000181467 RAP2B, member of RAS oncogene family 3 153162270-153170620 Predicted intracellular proteins Evidence at protein level Liver cancer:1.65e-4 (unfavourable), Ovarian cancer:9.21e-4 (favourable) Expressed in all Mixed placenta: 12.4 Mixed +ZBTB2 bA351K16.2, KIAA1483, ZNF437 ENSG00000181472 Zinc finger and BTB domain containing 2 6 151364117-151391548 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023136, HPA023137, HPA023458, HPA023487 Approved Supported Nucleoplasm
Cytosol Renal cancer:9.36e-6 (unfavourable), Liver cancer:1.21e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 50.0 Expressed in all +RNF135 MGC13061 ENSG00000181481 Ring finger protein 135 17 30968785-30999911 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021576, HPA052404 Approved Approved Vesicles Renal cancer:7.51e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.7 Mixed +OR6T1 ENSG00000181499 Olfactory receptor family 6 subfamily T member 1 11 123942785-123943873 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA060893 Uncertain Not detected Not detected testis: 0.6 Not detected +ACBD4 FLJ13322 ENSG00000181513 Acyl-CoA binding domain containing 4 17 45132600-45144181 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051772 Approved Approved Nucleus
Vesicles Pancreatic cancer:4.64e-4 (favourable), Liver cancer:4.76e-4 (favourable), Urothelial cancer:6.53e-4 (favourable) Expressed in all Expressed in all duodenum: 30.3 Mixed +OR8D4 ENSG00000181518 Olfactory receptor family 8 subfamily D member 4 11 123906146-123907476 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +SGSH HSS, MPS3A, SFMD ENSG00000181523 N-sulfoglucosamine sulfohydrolase 17 80206716-80220923 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023436, HPA023451 Enhanced Renal cancer:2.66e-4 (unfavourable), Lung cancer:2.72e-4 (favourable), Pancreatic cancer:3.10e-4 (favourable), Testis cancer:5.37e-4 (unfavourable), Liver cancer:7.71e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 36.3 Mixed +MAB21L2 ENSG00000181541 Mab-21 like 2 4 150581922-150584693 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049324, HPA059864 Enhanced Nucleus
Cytosol Tissue enhanced Tissue enhanced colon: 18.3;smooth muscle: 26.2 small intestine: 12.4 Group enriched 20 HHSteC: 4.9;SH-SY5Y: 16.0 +FANCB FAAP95, FAB, FLJ34064 ENSG00000181544 Fanconi anemia complementation group B X 14843407-14873069 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003124 Uncertain Mixed Mixed bone marrow: 2.4 Mixed +EDDM3B FAM12B, HE3-BETA ENSG00000181552 Epididymal protein 3B 14 20768427-20770948 Predicted secreted proteins Evidence at protein level HPA001323 Supported Not detected Tissue enriched 234 epididymis: 3239.8 seminal vesicle: 13.8 Cell line enhanced BEWO: 1.3;NB-4: 1.7 +SETD2 FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A ENSG00000181555 SET domain containing 2 3 47016429-47163967 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042451 Approved Approved Nuclear speckles
Cytosol Renal cancer:7.99e-6 (favourable), Melanoma:8.19e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 31.8 Expressed in all +EDDM3A FAM12A, HE3-ALPHA ENSG00000181562 Epididymal protein 3A 14 20745892-20748380 Predicted secreted proteins Evidence at protein level HPA049952 Approved Not detected Tissue enriched 15 epididymis: 780.6 seminal vesicle: 50.6 Not detected +C6orf223 MGC45491 ENSG00000181577 Chromosome 6 open reading frame 223 6 44000580-44005958 Predicted intracellular proteins Evidence at transcript level HPA035765, HPA046117 Uncertain Approved Nucleoli fibrillar center Renal cancer:9.38e-5 (unfavourable), Liver cancer:4.59e-4 (unfavourable) Mixed Group enriched 10 breast: 22.7;lung: 5.6 duodenum: 1.3 Cell line enhanced A-431: 21.4;RPTEC TERT1: 25.1;THP-1: 9.6 +TMIE DFNB6 ENSG00000181585 Transmembrane inner ear 3 46701333-46710886 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA038298 Uncertain Uncertain Vesicles
Cytosol Tissue enriched Tissue enhanced adrenal gland: 7.4;cerebral cortex: 5.2 testis: 1.6 Cell line enhanced CAPAN-2: 2.2;EFO-21: 2.1;SH-SY5Y: 2.3 +MEX3D KIAA2031, OK/SW-cl.4, RKHD1, RNF193, Tino ENSG00000181588 Mex-3 RNA binding family member D 19 1554669-1568058 Predicted intracellular proteins Evidence at protein level HPA065385 Approved Expressed in all Mixed testis: 17.7 Expressed in all +OR52D1 ENSG00000181609 Olfactory receptor family 52 subfamily D member 1 11 5488685-5489749 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA046965 Uncertain Not detected Tissue enriched 13 testis: 1.2 all non-specific tissues: 0.0 Not detected +MRPS23 CGI-138, HSPC329, MRP-S23 ENSG00000181610 Mitochondrial ribosomal protein S23 17 57834781-57850056 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA023453 Supported Supported Nuclear membrane
Mitochondria Liver cancer:9.52e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 61.5 Expressed in all +OR52H1 ENSG00000181616 Olfactory receptor family 52 subfamily H member 1 11 5544561-5545523 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +FDCSP C4orf7, FDC-SP ENSG00000181617 Follicular dendritic cell secreted protein 4 70226071-70235252 Predicted secreted proteins Evidence at protein level HPA014326, CAB014890 Enhanced Lung cancer:1.32e-4 (favourable), Head and neck cancer:2.38e-4 (favourable) Tissue enhanced Tissue enhanced lymph node: 1014.2;salivary gland: 1371.2;tonsil: 2458.1 appendix: 359.2 Cell line enhanced HL-60: 1.0;K-562: 1.0;RH-30: 1.7;U-87 MG: 4.6 +GPR135 HUMNPIIY20, PAFR ENSG00000181619 G protein-coupled receptor 135 14 59429022-59465342 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA045337 Uncertain Mixed Tissue enhanced testis: 9.1 fallopian tube,parathyroid gland: 5.0 Mixed +SLX1B GIYD2, MGC5178 ENSG00000181625 SLX1 homolog B, structure-specific endonuclease subunit 16 29454501-29458219 Predicted intracellular proteins Evidence at protein level HPA047038 Uncertain Approved Nucleoplasm Not detected Mixed small intestine: 29.4 Expressed in all +ANKRD62 DKFZp779B1634 ENSG00000181626 Ankyrin repeat domain 62 18 12093853-12129749 Predicted intracellular proteins Evidence at protein level HPA059835 Enhanced Not detected Tissue enriched 11 testis: 4.1 pancreas: 0.3 Not detected +P2RY13 FKSG77, GPR86, GPR94, P2Y13 ENSG00000181631 Purinergic receptor P2Y13 3 151326312-151329548 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA049047 Enhanced Expressed in all Tissue enhanced spleen: 51.2 appendix: 27.9 Not detected +TNFSF15 MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A ENSG00000181634 Tumor necrosis factor superfamily member 15 9 114784635-114806126 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012948, HPA046522 Approved Approved Nucleus
Nuclear membrane
Cytosol Mixed Mixed duodenum: 9.5 Cell line enhanced HaCaT: 11.6;hTEC/SVTERT24-B: 8.5;HUVEC TERT2: 13.6;RT4: 12.9;TIME: 6.2 +ZFP41 FLJ00028, FLJ38705, ZNF753 ENSG00000181638 ZFP41 zinc finger protein 8 143246821-143262705 Predicted intracellular proteins Evidence at transcript level HPA047232, HPA056268 Uncertain Uncertain Nucleus
Nucleoli
Plasma membrane Liver cancer:3.46e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 7.5 Mixed +PHLDA2 BWR1C, HLDA2, IPL, TSSC3 ENSG00000181649 Pleckstrin homology like domain family A member 2 11 2928273-2929455 Predicted intracellular proteins Evidence at protein level HPA003994 Uncertain Nucleoli Renal cancer:2.63e-6 (unfavourable), Liver cancer:4.22e-5 (unfavourable) Expressed in all Tissue enriched 8 placenta: 54.3 stomach: 6.6 Cell line enhanced HDLM-2: 185.5;PC-3: 149.3;SK-MEL-30: 101.3;WM-115: 170.7 +ATG9B APG9L2, FLJ14885, NOS3AS, SONE ENSG00000181652 Autophagy related 9B 7 151012209-151024499 Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced esophagus: 9.2;placenta: 5.8;skin: 13.5 testis: 3.8 Cell line enhanced BEWO: 12.5;CAPAN-2: 3.7 +GPR88 ENSG00000181656 G protein-coupled receptor 88 1 100538137-100542018 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at transcript level HPA007488 Approved Tissue enriched Group enriched 11 breast: 9.4;cerebral cortex: 3.1;liver: 4.9;ovary: 3.1;parathyroid gland: 4.9;spleen: 14.4 prostate: 0.6 Group enriched 8 HSkMC: 1.1;SCLC-21H: 2.3 +HKR1 ZNF875 ENSG00000181666 HKR1, GLI-Kruppel zinc finger family member 19 37312837-37369365 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036126, HPA044855 Approved Supported Nucleoplasm
Golgi apparatus
Mitochondria Prostate cancer:5.18e-5 (unfavourable), Pancreatic cancer:4.41e-4 (favourable) Expressed in all Expressed in all thyroid gland: 54.6 Expressed in all +PLAG1 ZNF912 ENSG00000181690 PLAG1 zinc finger 8 56160904-56211324 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA072290 Supported Nuclear speckles Mixed Mixed ovary: 5.9 Mixed +OR8H1 ENSG00000181693 Olfactory receptor family 8 subfamily H member 1 11 56290053-56291090 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR5T1 OR5T1P ENSG00000181698 Olfactory receptor family 5 subfamily T member 1 11 56275639-56276619 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA050952 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +YIPF6 FinGER6, MGC21416 ENSG00000181704 Yip1 domain family member 6 X 68498323-68537285 Predicted membrane proteins Evidence at protein level HPA003720 Uncertain Approved Vesicles Expressed in all Expressed in all thyroid gland: 32.8 Mixed +OR5T2 ENSG00000181718 Olfactory receptor family 5 subfamily T member 2 11 56232106-56233185 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZBTB20 DKFZp566F123, DPZF, ODA-8S, ZNF288 ENSG00000181722 Zinc finger and BTB domain containing 20 3 114314501-115147271 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015551, HPA016815 Approved Supported Nucleoplasm
Nuclear bodies Tissue enhanced Mixed testis: 17.4 Mixed +OR2Z1 OR2Z2 ENSG00000181733 Olfactory receptor family 2 subfamily Z member 1 19 8730954-8732009 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA048760 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +C3orf58 DIA1, HASF, MGC33365 ENSG00000181744 Chromosome 3 open reading frame 58 3 143971798-144048719 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048992 Approved Renal cancer:2.92e-7 (unfavourable) Expressed in all Mixed placenta: 53.9 Cell line enhanced AN3-CA: 136.9 +C5orf30 FLJ25291 ENSG00000181751 Chromosome 5 open reading frame 30 5 103258702-103278660 Predicted intracellular proteins Evidence at protein level HPA043434 Uncertain Liver cancer:1.78e-5 (unfavourable), Endometrial cancer:2.66e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 31.4 Cell line enhanced BJ: 149.2;U-138 MG: 113.8 +OR8K5 ENSG00000181752 Olfactory receptor family 8 subfamily K member 5 11 56159394-56160317 G-protein coupled receptors, Predicted membrane proteins No evidence Tissue enriched Not detected all non-specific tissues: 0.0 Not detected +AMIGO1 AMIGO, KIAA1163 ENSG00000181754 Adhesion molecule with Ig like domain 1 1 109504175-109509738 Predicted membrane proteins Evidence at protein level HPA046152 Approved Approved Nucleoplasm
Nuclear bodies Liver cancer:1.21e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 24.6 Cell line enhanced SCLC-21H: 9.8 +OR8H3 ENSG00000181761 Olfactory receptor family 8 subfamily H member 3 11 56122373-56123311 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR8H2 ENSG00000181767 Olfactory receptor family 8 subfamily H member 2 11 56105018-56106055 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +GPR3 ACCA ENSG00000181773 G protein-coupled receptor 3 1 27392644-27395814 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB006254 Uncertain Mixed Tissue enhanced cerebral cortex: 5.2 thyroid gland: 1.3 Cell line enhanced U-2197: 21.6 +TMEM252 C9orf71, MGC34760 ENSG00000181778 Transmembrane protein 252 9 68536580-68540867 Predicted membrane proteins Evidence at transcript level Renal cancer:1.75e-7 (favourable) Tissue enriched Tissue enhanced kidney: 37.5;small intestine: 25.7 esophagus: 6.8 Cell line enhanced PC-3: 1.1;RPTEC TERT1: 1.8;SK-BR-3: 1.0 +ODF3L2 C19orf19, FLJ40059 ENSG00000181781 Outer dense fiber of sperm tails 3 like 2 19 463346-474983 Predicted intracellular proteins Evidence at protein level HPA067973 Uncertain Not detected Group enriched 10 skeletal muscle: 2.7;testis: 7.6 spleen: 0.5 Not detected +OR5AS1 ENSG00000181785 Olfactory receptor family 5 subfamily AS member 1 11 56030419-56031393 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ACTL9 MGC33407 ENSG00000181786 Actin like 9 19 8697397-8698822 Predicted intracellular proteins Evidence at protein level HPA019231, HPA026693 Uncertain Not detected Tissue enriched 501 testis: 50.0 all non-specific tissues: 0.0 Not detected +SIAH2 ENSG00000181788 Siah E3 ubiquitin protein ligase 2 3 150741127-150763477 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA061293, CAB069930 Approved Supported Nucleoplasm
Vesicles Pancreatic cancer:8.21e-5 (unfavourable), Breast cancer:1.17e-4 (favourable) Expressed in all Expressed in all adrenal gland: 95.3 Expressed in all +COPG1 COPG ENSG00000181789 Coatomer protein complex subunit gamma 1 3 129249606-129277773 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037866, HPA037867, HPA045712 Supported Supported Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:1.22e-6 (unfavourable) Expressed in all Expressed in all epididymis: 191.9 Expressed in all +ADGRB1 BAI1 ENSG00000181790 Adhesion G protein-coupled receptor B1 8 142449430-142545009 Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enriched 10 cerebral cortex: 22.0 spleen: 2.2 Cell line enhanced AN3-CA: 10.7;RPMI-8226: 12.0;U-2 OS: 11.7 +OR6S1 OR6S1Q ENSG00000181803 Olfactory receptor family 6 subfamily S member 1 14 20640696-20641691 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +SLC9A9 FLJ35613, NHE9 ENSG00000181804 Solute carrier family 9 member A9 3 143265222-143848531 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA058234 Approved Renal cancer:5.57e-7 (unfavourable), Lung cancer:8.18e-4 (favourable) Expressed in all Mixed placenta: 22.3 Cell line enhanced ASC TERT1: 17.2;Karpas-707: 44.4;RPMI-8226: 20.5;U-266/70: 21.8 +LSM10 MGC15749 ENSG00000181817 LSM10, U7 small nuclear RNA associated 1 36391238-36397892 Predicted intracellular proteins Evidence at protein level HPA048469 Supported Nucleus
Nuclear bodies Renal cancer:6.40e-6 (unfavourable), Liver cancer:1.83e-4 (unfavourable), Pancreatic cancer:4.89e-4 (favourable) Expressed in all Expressed in all lymph node: 60.3 Expressed in all +RELL1 ENSG00000181826 RELT like 1 4 37590800-37686376 Predicted membrane proteins Evidence at protein level HPA013377 Approved Supported Plasma membrane
Microtubules Expressed in all Mixed thyroid gland: 27.7 Cell line enhanced RH-30: 57.4 +RFX7 FLJ12994, RFXDC2 ENSG00000181827 Regulatory factor X7 15 56087280-56243266 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035462 Supported Approved Nucleus
Nuclear membrane Renal cancer:1.12e-5 (unfavourable) Expressed in all Mixed testis: 8.2 Expressed in all +SLC35C1 FLJ11320, FUCT1 ENSG00000181830 Solute carrier family 35 member C1 11 45804072-45813015 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA064001 Enhanced Supported Golgi apparatus Thyroid cancer:3.64e-4 (favourable) Expressed in all Expressed in all esophagus: 29.4 Expressed in all +TIGIT DKFZp667A205, FLJ39873, VSIG9, VSTM3 ENSG00000181847 T-cell immunoreceptor with Ig and ITIM domains 3 114276913-114310288 Predicted membrane proteins Evidence at protein level Head and neck cancer:3.96e-4 (favourable), Cervical cancer:5.43e-4 (favourable) Mixed Tissue enhanced lymph node: 44.3 spleen: 20.5 Cell line enhanced HDLM-2: 1.2 +RNF41 NRDP1, SBBI03 ENSG00000181852 Ring finger protein 41 12 56202175-56221933 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016812 Approved Approved Nucleus
Nuclear bodies
Midbody ring Renal cancer:2.52e-5 (favourable), Liver cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all prostate: 55.3 Expressed in all +SLC2A4 GLUT4 ENSG00000181856 Solute carrier family 2 member 4 17 7281667-7288257 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB016544 Enhanced Mixed Tissue enhanced heart muscle: 32.6;skeletal muscle: 45.0 adipose tissue: 21.8 Cell line enhanced Hep G2: 3.7 +FTMT MtF ENSG00000181867 Ferritin mitochondrial 5 121851955-121852833 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 471 testis: 47.1 all non-specific tissues: 0.0 Not detected +IBA57 C1orf69, FLJ12734 ENSG00000181873 IBA57 homolog, iron-sulfur cluster assembly 1 228165815-228182257 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030555, HPA030556, HPA030557 Approved Supported Mitochondria Renal cancer:1.71e-9 (favourable) Expressed in all Mixed parathyroid gland: 4.1 Mixed +CLDN7 CEPTRL2, CPETRL2, Hs.84359 ENSG00000181885 Claudin 7 17 7259903-7263983 Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB013063, HPA014703, HPA073662 Enhanced Approved Vesicles
Cell Junctions Renal cancer:8.96e-11 (favourable), Thyroid cancer:1.85e-4 (favourable), Stomach cancer:4.09e-4 (favourable) Expressed in all Mixed small intestine: 350.1 Cell line enhanced BEWO: 162.4;CAPAN-2: 304.6;HaCaT: 644.4;MCF7: 198.9;SK-BR-3: 225.1 +ZNF329 FLJ12586 ENSG00000181894 Zinc finger protein 329 19 58126252-58155110 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044373 Uncertain Approved Nucleoplasm
Nuclear membrane Renal cancer:8.58e-9 (favourable) Expressed in all Mixed parathyroid gland: 16.9 Mixed +ZNF101 DKFZp570I0164, HZF12 ENSG00000181896 Zinc finger protein 101 19 19668796-19683509 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023449, HPA055486 Uncertain Cervical cancer:5.76e-5 (favourable), Stomach cancer:1.11e-4 (favourable), Head and neck cancer:2.15e-4 (favourable), Ovarian cancer:2.26e-4 (favourable), Urothelial cancer:4.37e-4 (favourable), Lung cancer:6.65e-4 (favourable) Expressed in all Tissue enhanced lymph node: 31.4 tonsil: 22.3 Expressed in all +OR4C6 ENSG00000181903 Olfactory receptor family 4 subfamily C member 6 11 55665167-55666096 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected lymph node,tonsil: 0.1 Group enriched 7 CAPAN-2: 3.3;Karpas-707: 2.9 +C5orf24 FLJ37562 ENSG00000181904 Chromosome 5 open reading frame 24 5 134845680-134859737 Predicted intracellular proteins Evidence at protein level HPA057749, HPA062502 Uncertain Supported Nucleus Renal cancer:5.86e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 49.8 Expressed in all +ADO C10orf22, FLJ14547 ENSG00000181915 2-aminoethanethiol dioxygenase 10 62804857-62808483 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039194, HPA040437 Approved Liver cancer:8.01e-5 (unfavourable) Expressed in all Expressed in all testis: 70.7 Expressed in all +COA4 CHCHD8, CMC3, E2IG2 ENSG00000181924 Cytochrome c oxidase assembly factor 4 homolog 11 73872667-73876988 Predicted intracellular proteins Evidence at protein level HPA040126 Approved Approved Nucleus
Nucleoli fibrillar center
Mitochondria Renal cancer:2.14e-4 (unfavourable), Ovarian cancer:3.87e-4 (favourable) Expressed in all Expressed in all adrenal gland: 81.4 Expressed in all +OR4P4 OR4P3P ENSG00000181927 Olfactory receptor family 4 subfamily P member 4 11 55638358-55639296 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA059458 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +PRKAG1 ENSG00000181929 Protein kinase AMP-activated non-catalytic subunit gamma 1 12 49002274-49019197 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA077805 Approved Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:2.84e-7 (unfavourable), Renal cancer:1.83e-4 (favourable) Expressed in all Expressed in all breast: 56.9 Expressed in all +GINS3 FLJ13912, PSF3 ENSG00000181938 GINS complex subunit 3 16 58295080-58406144 Predicted intracellular proteins Evidence at protein level HPA041216, HPA048209 Uncertain Enhanced Nucleoplasm Expressed in all Mixed testis: 10.5 Expressed in all +OR4C15 ENSG00000181939 Olfactory receptor family 4 subfamily C member 15 11 55554307-55555419 G-protein coupled receptors, Predicted membrane proteins No evidence HPA061939 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR4A15 ENSG00000181958 Olfactory receptor family 4 subfamily A member 15 11 55367884-55368918 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR4A16 OR4A16Q ENSG00000181961 Olfactory receptor family 4 subfamily A member 16 11 55343201-55344187 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.1 Not detected +OR52K2 ENSG00000181963 Olfactory receptor family 52 subfamily K member 2 11 4449295-4450361 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected bone marrow: 0.1 Not detected +NEUROG1 AKA, bHLHa6, Math4C, NEUROD3, ngn1 ENSG00000181965 Neurogenin 1 5 135534282-135535949 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enriched Not detected all non-specific tissues: 0.0 Not detected +CCDC149 DKFZp761B107 ENSG00000181982 Coiled-coil domain containing 149 4 24806117-24980204 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044158, HPA047913 Uncertain Approved Nucleoli Endometrial cancer:6.63e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 24.1 Cell line enhanced U-87 MG: 30.1 +MRPS11 FLJ22512, FLJ23406, HCC-2 ENSG00000181991 Mitochondrial ribosomal protein S11 15 88467453-88480773 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043752, HPA050345 Enhanced Supported Mitochondria Cervical cancer:3.60e-4 (favourable), Ovarian cancer:4.75e-4 (favourable) Expressed in all Expressed in all thyroid gland: 13.6 Expressed in all +SNRPE Sm-E ENSG00000182004 Small nuclear ribonucleoprotein polypeptide E 1 203861603-203870550 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.38e-5 (unfavourable), Ovarian cancer:3.95e-4 (favourable) Expressed in all Expressed in all breast: 97.4 Expressed in all +RTKN2 bA531F24.1, Em:AC024597.2, FLJ39352, PLEKHK1 ENSG00000182010 Rhotekin 2 10 62183035-62268707 Predicted intracellular proteins Evidence at protein level HPA037946, HPA038446 Enhanced Approved Nucleoplasm
Mitochondria Mixed Tissue enriched 8 lung: 121.3 testis: 14.7 Cell line enhanced A-431: 40.4 +PNMAL1 FLJ10781, KIAA1183L ENSG00000182013 Paraneoplastic Ma antigen family like 1 19 46466491-46471563 Predicted intracellular proteins Evidence at protein level HPA012956 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Mixed Tissue enhanced cerebral cortex: 133.9 testis: 42.5 Cell line enhanced HAP1: 33.8;K-562: 32.4;LHCN-M2: 29.9;SH-SY5Y: 33.2 +CHST15 BRAG, GALNAC4S-6ST, KIAA0598 ENSG00000182022 Carbohydrate sulfotransferase 15 10 124007666-124093607 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017584 Approved Approved Centrosome
Cytosol Renal cancer:2.22e-7 (unfavourable) Expressed in all Expressed in all ovary: 45.6 Cell line enhanced REH: 82.5 +ADIG MGC39724, RP5-1100H13.2, SMAF1 ENSG00000182035 Adipogenin 20 38581195-38588463 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA041124 Uncertain Tissue enhanced Group enriched 10 epididymis: 5.1;testis: 16.1;thyroid gland: 3.4 seminal vesicle: 0.8 Not detected +USH1G ANKS4A, FLJ33924, Sans ENSG00000182040 USH1 protein network component sans 17 74916084-74923256 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024360 Uncertain Tissue enhanced Tissue enhanced epididymis: 2.3;esophagus: 2.6;skin: 1.8 testis: 1.4 Cell line enhanced HaCaT: 1.6;hTCEpi: 1.2;K-562: 1.2;MCF7: 1.5;U-2 OS: 1.0 +MGAT4C HGNT-IV-H ENSG00000182050 MGAT4 family member C 12 85955666-86838904 Enzymes, Predicted membrane proteins Evidence at transcript level HPA016418 Approved Tissue enriched Group enriched 5 cerebral cortex: 5.9;epididymis: 6.7;testis: 5.5;thyroid gland: 15.9 adrenal gland: 1.6 Group enriched 13 NTERA-2: 8.7;SCLC-21H: 4.4 +TRIM49B ENSG00000182053 Tripartite motif containing 49B 11 49027501-49038451 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.1 Not detected +IDH2 ENSG00000182054 Isocitrate dehydrogenase (NADP(+)) 2, mitochondrial 15 90083045-90102504 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007831 Enhanced Supported Mitochondria Cervical cancer:5.15e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 450.0 Expressed in all +OR52A1 HPFH1OR ENSG00000182070 Olfactory receptor family 52 subfamily A member 1 11 5151009-5186382 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +PTCHD3 FLJ44037, PTR ENSG00000182077 Patched domain containing 3 10 27398187-27414368 Predicted membrane proteins Evidence at protein level HPA044613 Enhanced Not detected Tissue enriched 9 testis: 4.1 adipose tissue: 0.4 Not detected +OR6B2 OR6B2P ENSG00000182083 Olfactory receptor family 6 subfamily B member 2 2 240028965-240030456 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047529 Uncertain Not detected Not detected testis: 0.5 Not detected +TMEM259 ASBABP1, C19orf6, MBRL, MGC4022 ENSG00000182087 Transmembrane protein 259 19 1009648-1021179 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042669, HPA054801 Approved Approved Nuclear speckles
Endoplasmic reticulum Stomach cancer:8.92e-6 (favourable), Endometrial cancer:1.01e-4 (favourable) Expressed in all Expressed in all spleen: 129.7 Expressed in all +WRB CHD5, GET1 ENSG00000182093 Tryptophan rich basic protein 21 39380244-39428528 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018527 Approved Expressed in all Expressed in all fallopian tube: 109.1 Expressed in all +TNRC18 CAGL79, KIAA1856, TNRC18A ENSG00000182095 Trinucleotide repeat containing 18 7 5306790-5425414 Predicted intracellular proteins Evidence at protein level HPA020730, HPA024251 Uncertain Approved Nucleoplasm
Nuclear membrane
Mitochondria
Cytosol Expressed in all Expressed in all parathyroid gland: 86.4 Expressed in all +FAM181B LOC220382, MGC33846 ENSG00000182103 Family with sequence similarity 181 member B 11 82729941-82733864 Predicted intracellular proteins Evidence at transcript level HPA066861 Approved Approved Nuclear membrane
Mitochondria Endometrial cancer:8.07e-4 (favourable) Tissue enriched Tissue enriched 20 cerebral cortex: 17.5 adrenal gland,fallopian tube: 0.8 Cell line enhanced RT4: 1.9;SH-SY5Y: 1.3;U-2 OS: 1.3 +TMEM30B CDC50B ENSG00000182107 Transmembrane protein 30B 14 61277370-61281840 Predicted membrane proteins, Transporters Evidence at protein level HPA043162 Uncertain Renal cancer:5.89e-5 (favourable) Mixed Mixed parathyroid gland: 82.1 Cell line enhanced A-431: 53.2;CAPAN-2: 42.5;MCF7: 29.9;RT4: 66.7 +DEXI MYLE ENSG00000182108 Dexi homolog 16 10928891-10942460 Predicted membrane proteins Evidence at transcript level HPA041511 Approved Approved Nuclear speckles
Cytosol Pancreatic cancer:4.23e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 45.0 Expressed in all +ZNF716 FLJ46189 ENSG00000182111 Zinc finger protein 716 7 57450177-57473546 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enriched Not detected testis: 0.9 Not detected +NOP10 MGC70651, NOLA3, NOP10P ENSG00000182117 NOP10 ribonucleoprotein 15 34341713-34343177 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA059198 Supported Supported Nuclear bodies Endometrial cancer:1.48e-5 (favourable) Expressed in all Expressed in all epididymis: 289.4 Expressed in all +FAM89A C1orf153, MGC15887 ENSG00000182118 Family with sequence similarity 89 member A 1 231018958-231040246 Predicted intracellular proteins Evidence at protein level HPA059052, HPA059578 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:1.75e-5 (unfavourable) Expressed in all Expressed in all placenta: 98.7 Cell line enhanced BEWO: 141.2 +KCNIP1 KCHIP1 ENSG00000182132 Potassium voltage-gated channel interacting protein 1 5 170353487-170736632 Predicted intracellular proteins Evidence at protein level HPA022864 Uncertain Tissue enriched Tissue enhanced cerebral cortex: 40.4;epididymis: 26.3 seminal vesicle: 7.9 Cell line enriched 17 RPTEC TERT1: 43.9 +TDRKH TDRD2 ENSG00000182134 Tudor and KH domain containing 1 151770107-151791416 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016419, HPA019625 Approved Approved Centrosome
Cytosol Endometrial cancer:1.66e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 76.8;testis: 40.1 cerebral cortex: 13.0 Mixed +ZNF708 KOX8, ZNF15, ZNF15L1 ENSG00000182141 Zinc finger protein 708 19 21291160-21329425 Predicted intracellular proteins, Transcription factors Evidence at protein level Ovarian cancer:3.53e-4 (favourable), Glioma:6.32e-4 (favourable) Expressed in all Mixed cerebral cortex: 17.7 Mixed +IST1 KIAA0174 ENSG00000182149 IST1, ESCRT-III associated factor 16 71845996-71931199 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041802, HPA054532 Approved Supported Vesicles Renal cancer:4.55e-4 (favourable), Urothelial cancer:8.88e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 180.4 Expressed in all +ERCC6L2 C9orf102, FLJ37706, RAD26L ENSG00000182150 ERCC excision repair 6 like 2 9 95875701-96014571 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021260 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:8.70e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 27.0 Expressed in all +MRPL41 BMRP, MRP-L27, MRPL27, PIG3, RPML27 ENSG00000182154 Mitochondrial ribosomal protein L41 9 137551199-137552555 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA024550, HPA027160 Supported Supported Mitochondria Expressed in all Expressed in all skeletal muscle: 59.8 Expressed in all +ENPP7 alk-SMase, NPP7 ENSG00000182156 Ectonucleotide pyrophosphatase/phosphodiesterase 7 17 79730919-79742222 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA024603 Approved Tissue enriched Group enriched 22 duodenum: 45.7;small intestine: 110.2 kidney: 3.5 Cell line enhanced Karpas-707: 1.4;U-266/70: 2.1 +CREB3L2 BBF2H7, TCAG_1951439 ENSG00000182158 CAMP responsive element binding protein 3 like 2 7 137874979-138002067 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA015068, HPA015534 Uncertain Supported Nucleoplasm
Endoplasmic reticulum Expressed in all Expressed in all parathyroid gland: 110.9 Mixed +P2RY8 P2Y8 ENSG00000182162 Purinergic receptor P2Y8 X 1462572-1537107 Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003631 Enhanced Head and neck cancer:7.80e-5 (favourable), Liver cancer:1.73e-4 (favourable), Pancreatic cancer:6.54e-4 (favourable) Expressed in all Tissue enhanced lymph node: 47.6 tonsil: 31.3 Cell line enhanced Daudi: 87.1;U-266/70: 75.0;U-698: 136.4 +UNC5C ENSG00000182168 Unc-5 netrin receptor C 4 95162504-95549206 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced thyroid gland: 20.0 adrenal gland: 11.6 Group enriched 6 AF22: 17.6;SH-SY5Y: 82.9 +MRGPRG GPR169, mrgG ENSG00000182170 MAS related GPR family member G 11 3217944-3218813 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA058909 Uncertain Not detected Tissue enriched 15 testis: 1.5 all non-specific tissues: 0.0 Cell line enhanced SCLC-21H: 1.0 +TSEN54 SEN54, SEN54L ENSG00000182173 TRNA splicing endonuclease subunit 54 17 75516060-75524739 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053097 Uncertain Liver cancer:8.06e-6 (unfavourable), Pancreatic cancer:2.62e-5 (favourable), Stomach cancer:7.78e-5 (favourable), Urothelial cancer:8.54e-4 (favourable) Expressed in all Expressed in all skin: 20.4 Expressed in all +RGMA RGM, RGMa ENSG00000182175 Repulsive guidance molecule family member a 15 93035273-93089204 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB012343, HPA039880, HPA044222 Approved Supported Nucleoplasm
Cytosol Lung cancer:2.78e-4 (favourable) Tissue enriched Tissue enhanced cerebral cortex: 116.6;smooth muscle: 84.8 skeletal muscle: 42.6 Cell line enhanced AF22: 49.7;NTERA-2: 22.5 +ASB18 ENSG00000182177 Ankyrin repeat and SOCS box containing 18 2 236194872-236264409 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA068447 Approved Not detected Group enriched 8 heart muscle: 4.3;skeletal muscle: 3.6;testis: 1.0 cerebral cortex: 0.4 Not detected +UBA7 D8, UBA1B, UBE1L, UBE2 ENSG00000182179 Ubiquitin like modifier activating enzyme 7 3 49805207-49813946 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB015444, HPA058182 Approved Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:1.04e-5 (unfavourable), Urothelial cancer:1.48e-4 (favourable), Breast cancer:1.55e-4 (favourable) Expressed in all Expressed in all spleen: 65.5 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 55.3;HMC-1: 91.3 +MRPS16 CGI-132 ENSG00000182180 Mitochondrial ribosomal protein S16 10 73248843-73252693 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050081, HPA054538 Supported Supported Mitochondria
Cytosol Liver cancer:4.57e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 30.4 Expressed in all +FAM159A MGC52498 ENSG00000182183 Family with sequence similarity 159 member A 1 52633344-52669683 Predicted membrane proteins Evidence at transcript level HPA030744 Uncertain Mixed Tissue enhanced lymph node: 8.8;tonsil: 6.6 spleen: 4.5 Cell line enhanced Daudi: 3.8;Karpas-707: 9.0;RPMI-8226: 11.8 +RAD51B hREC2, R51H2, RAD51L1, REC2 ENSG00000182185 RAD51 paralog B 14 67819779-68730218 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB016191, HPA051869 Enhanced Approved Nucleoplasm
Nuclear bodies Mixed Mixed epididymis: 11.0 Expressed in all +CRYGB CRYG2 ENSG00000182187 Crystallin gamma B 2 208142573-208146168 Disease related genes, Predicted intracellular proteins Evidence at protein level Group enriched Not detected testis: 0.5 Not detected +LDOC1 BCUR1, Mar7, Mart7 ENSG00000182195 LDOC1, regulator of NFKB signaling X 141175745-141177125 Predicted intracellular proteins Evidence at protein level HPA051768, HPA061842 Approved Supported Nucleus
Nucleoli Expressed in all Mixed cerebral cortex: 73.0 Cell line enhanced MCF7: 106.5;PC-3: 156.8 +ARL6IP4 SFRS20, SR-25, SRp25, SRrp37 ENSG00000182196 ADP ribosylation factor like GTPase 6 interacting protein 4 12 122980060-122982913 Predicted intracellular proteins Evidence at protein level HPA052098 Approved Urothelial cancer:1.08e-4 (favourable) Expressed in all Expressed in all adrenal gland: 186.0 Expressed in all +EXT1 LGCR, LGS, ttv ENSG00000182197 Exostosin glycosyltransferase 1 8 117794490-118111853 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044394 Uncertain Lung cancer:1.20e-5 (unfavourable), Thyroid cancer:4.64e-4 (unfavourable), Cervical cancer:7.04e-4 (unfavourable) Expressed in all Mixed duodenum: 31.6 Cell line enhanced BJ hTERT+: 193.5;fHDF/TERT166: 189.8 +SHMT2 SHMT ENSG00000182199 Serine hydroxymethyltransferase 2 12 57229327-57234935 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020543, HPA020549 Enhanced Enhanced Microtubules
Mitochondria Renal cancer:4.84e-8 (unfavourable), Breast cancer:8.37e-5 (unfavourable) Expressed in all Expressed in all liver: 74.8 Expressed in all +MOB2 HCCA2 ENSG00000182208 MOB kinase activator 2 11 1469457-1501247 Predicted intracellular proteins Evidence at protein level HPA046313 Uncertain Supported Nucleus
Nucleoli
Cytosol Renal cancer:2.02e-4 (favourable), Glioma:7.86e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 70.7 Expressed in all +HHIPL1 KIAA1822 ENSG00000182218 HHIP like 1 14 99645110-99680569 Predicted secreted proteins Evidence at transcript level HPA052767 Approved Mixed Tissue enhanced cerebral cortex: 6.6 smooth muscle: 2.6 Cell line enhanced EFO-21: 2.9;fHDF/TERT166: 4.3;SiHa: 3.9;THP-1: 2.6 +ATP6AP2 APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR ENSG00000182220 ATPase H+ transporting accessory protein 2 X 40579372-40606848 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA003156 Approved Renal cancer:2.01e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 893.4 Expressed in all +ZAR1 Z3CXXC6 ENSG00000182223 Zygote arrest 1 4 48490252-48494389 Plasma proteins, Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced testis: 1.1 bone marrow: 0.2 Not detected +CYB5D1 FLJ32499 ENSG00000182224 Cytochrome b5 domain containing 1 17 7857746-7862282 Predicted intracellular proteins Evidence at protein level HPA021632 Uncertain Approved Nucleoli
Golgi apparatus Mixed Expressed in all fallopian tube: 41.9 Expressed in all +FAM153B ENSG00000182230 Family with sequence similarity 153 member B 5 176060689-176132258 Predicted intracellular proteins Evidence at transcript level HPA042585, HPA044022, HPA046691, HPA052337, HPA055498 Uncertain Not detected Tissue enhanced ovary: 8.4;testis: 15.4 cerebral cortex: 4.1 Cell line enriched 6 U-2 OS: 1.1 +BACE2 AEPLC, ALP56, CEAP1, DRAP ENSG00000182240 Beta-site APP-cleaving enzyme 2 21 41167801-41282518 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035416 Approved Cervical cancer:1.11e-4 (unfavourable), Glioma:8.13e-4 (unfavourable) Expressed in all Mixed stomach: 30.5 Cell line enhanced SK-BR-3: 43.8;WM-115: 41.2 +UBE2E2 FLJ25157, UbcH8 ENSG00000182247 Ubiquitin conjugating enzyme E2 E2 3 23203020-23591793 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003303, HPA028872, HPA030445, CAB073417 Approved Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 40.1 Mixed +SYNM DMN, KIAA0353, SYN ENSG00000182253 Synemin 15 99098217-99135593 Predicted intracellular proteins Evidence at protein level CAB017192, HPA040066, HPA044200 Enhanced Expressed in all Tissue enhanced seminal vesicle: 404.4 smooth muscle: 227.4 Cell line enhanced A549: 33.4;HeLa: 36.9;WM-115: 122.8 +KCNA4 HK1, HPCN2, KCNA4L, Kv1.4 ENSG00000182255 Potassium voltage-gated channel subfamily A member 4 11 30009741-30017023 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level CAB001977, HPA016422 Approved Not detected Tissue enhanced adrenal gland: 7.9;cerebral cortex: 4.3 heart muscle: 1.4 Not detected +GABRG3 ENSG00000182256 Gamma-aminobutyric acid type A receptor gamma3 subunit 15 26971282-27541991 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054010 Supported Tissue enhanced Tissue enhanced prostate: 10.6;testis: 16.5 cerebral cortex: 4.2 Cell line enhanced K-562: 4.0;PC-3: 5.1;U-87 MG: 14.0 +PRR34 C22orf26, FLJ10945 ENSG00000182257 Proline rich 34 22 46049478-46054144 Predicted intracellular proteins Evidence at protein level Not detected Mixed skeletal muscle: 1.7 Cell line enhanced HeLa: 3.9 +NLRP10 CLR11.1, NALP10, NOD8, PAN5, Pynod ENSG00000182261 NLR family pyrin domain containing 10 11 7959424-7965426 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039498, HPA040101 Uncertain Approved Nucleoplasm
Nuclear membrane Tissue enhanced Tissue enriched 12 skin: 3.2 breast: 0.2 Cell line enhanced A-431: 14.7;BJ: 4.2;HBF TERT88: 6.6 +FIGN ENSG00000182263 Fidgetin, microtubule severing factor 2 163593396-163736012 Predicted intracellular proteins Evidence at protein level HPA034987, HPA057919 Approved Approved Nucleoplasm
Vesicles
Plasma membrane
Cell Junctions
Cytosol Mixed Mixed ovary: 5.1 Cell line enhanced AF22: 18.3 +IZUMO1 IZUMO, MGC34799, OBF ENSG00000182264 Izumo sperm-egg fusion 1 19 48740852-48746909 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA038104 Enhanced Not detected Tissue enriched 22 testis: 19.0 lung: 0.8 Not detected +TMIGD1 TMIGD, UNQ9372 ENSG00000182271 Transmembrane and immunoglobulin domain containing 1 17 30316333-30334059 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA021946 Approved Mitochondria Tissue enhanced Group enriched 23 colon: 81.8;rectum: 109.8;small intestine: 162.9 kidney: 5.1 Not detected +B4GALNT4 FLJ25045, NGalNAc-T1 ENSG00000182272 Beta-1,4-N-acetyl-galactosaminyltransferase 4 11 369796-382116 Enzymes, Predicted secreted proteins Evidence at protein level HPA053126 Uncertain Approved Nucleoplasm
Microtubules
Cytokinetic bridge
Mitotic spindle Mixed Tissue enhanced cerebral cortex: 30.9;ovary: 11.7 endometrium,fallopian tube: 6.9 Cell line enhanced AF22: 38.5;NTERA-2: 34.8;SCLC-21H: 50.7;SH-SY5Y: 55.6 +AP1S2 MRX59, MRXS5, PGS, SIGMA1B ENSG00000182287 Adaptor related protein complex 1 sigma 2 subunit X 15825806-15855014 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049894, HPA060945 Enhanced Supported Golgi apparatus
Vesicles Ovarian cancer:5.53e-6 (favourable), Breast cancer:9.86e-4 (favourable) Expressed in all Tissue enriched 7 epididymis: 920.5 smooth muscle: 126.9 Expressed in all +C8orf33 FLJ20989 ENSG00000182307 Chromosome 8 open reading frame 33 8 145052378-145056030 Predicted intracellular proteins Evidence at protein level HPA024812, HPA026104 Approved Uncertain Nucleoplasm
Plasma membrane Breast cancer:2.77e-4 (unfavourable), Liver cancer:8.95e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 26.2 Expressed in all +DCAF4L1 WDR21B ENSG00000182308 DDB1 and CUL4 associated factor 4 like 1 4 41981696-41986467 Predicted intracellular proteins Evidence at protein level CAB073535 Enhanced Tissue enriched Tissue enriched 122 testis: 45.7 appendix,skin: 0.3 Mixed +SPACA6 LET7EH, LINC00085, NCRNA00085, SPACA6P ENSG00000182310 Sperm acrosome associated 6 19 51693340-51712387 Predicted membrane proteins Evidence at protein level Renal cancer:1.98e-10 (unfavourable), Endometrial cancer:2.73e-4 (unfavourable) Mixed Tissue enriched 19 testis: 4.0 adipose tissue: 0.2 Not detected +MBD3L3 ENSG00000182315 Methyl-CpG binding domain protein 3 like 3 19 7056209-7058640 Predicted intracellular proteins No evidence HPA051259 Uncertain Not detected Not detected testis: 0.3 Not detected +ZSCAN22 HKR2, ZNF50 ENSG00000182318 Zinc finger and SCAN domain containing 22 19 58327019-58342332 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006471 Uncertain Approved Plasma membrane
Actin filaments
Cytosol Expressed in all Mixed parathyroid gland: 3.3 Cell line enhanced HEK 293: 13.4 +KCNJ14 IRK4, Kir2.4 ENSG00000182324 Potassium voltage-gated channel subfamily J member 14 19 48455509-48466980 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA071765 Approved Nucleoli Mixed Mixed skin,testis: 2.1 Mixed +FBXL6 FBL6 ENSG00000182325 F-box and leucine rich repeat protein 6 8 144355431-144359376 Predicted intracellular proteins Evidence at protein level HPA008867 Approved Nucleus Renal cancer:4.49e-10 (unfavourable) Expressed in all Mixed duodenum: 9.0 Mixed +C1S ENSG00000182326 Complement C1s 12 6988259-7071032 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016722, HPA018852 Supported Approved Nucleus
Cytosol Renal cancer:7.44e-15 (unfavourable), Liver cancer:7.73e-4 (favourable) Expressed in all Expressed in all liver: 1326.7 Cell line enhanced ASC diff: 521.6;ASC TERT1: 703.0;BJ hTERT+: 271.2;HSkMC: 390.5 +GLTPD2 ENSG00000182327 Glycolipid transfer protein domain containing 2 17 4788959-4790390 Predicted secreted proteins Evidence at protein level HPA058295, HPA065267 Uncertain Approved Vesicles Tissue enriched Tissue enhanced duodenum: 11.0;kidney: 12.8;liver: 13.8 small intestine: 7.2 Cell line enhanced CACO-2: 8.6;Hep G2: 9.4 +KIAA2012 ENSG00000182329 KIAA2012 2 202073289-202205203 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 9 fallopian tube: 14.7 testis: 1.5 Not detected +PRAMEF8 ENSG00000182330 PRAME family member 8 1 13281035-13285174 Predicted intracellular proteins Evidence at transcript level HPA049887, HPA051704 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +LIPF HGL, HLAL ENSG00000182333 Lipase F, gastric type 10 88664441-88678814 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level HPA045930 Enhanced Tissue enriched Tissue enriched 86 stomach: 22415.5 duodenum: 259.5 Cell line enhanced HMC-1: 3.6;MOLT-4: 2.7;NTERA-2: 3.5;THP-1: 4.5;U-2 OS: 2.4;U-266/70: 2.4 +OR5P3 JCG1 ENSG00000182334 Olfactory receptor family 5 subfamily P member 3 11 7825037-7825972 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA060787 Uncertain Not detected Not detected epididymis,skin: 0.1 Not detected +DAOA G72 ENSG00000182346 D-amino acid oxidase activator 13 105465867-105491034 Predicted intracellular proteins Evidence at protein level HPA053114 Approved Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF804B FLJ32110 ENSG00000182348 Zinc finger protein 804B 7 88759368-89337057 Predicted intracellular proteins Evidence at protein level HPA026702 Uncertain Not detected Tissue enriched 7 thyroid gland: 7.3 kidney: 0.9 Not detected +KBTBD3 BKLHD3 ENSG00000182359 Kelch repeat and BTB domain containing 3 11 106051098-106077765 Predicted intracellular proteins Evidence at protein level HPA047385 Uncertain Renal cancer:3.42e-7 (favourable) Mixed Mixed thyroid gland: 7.7 Mixed +YBEY C21orf57 ENSG00000182362 YbeY metallopeptidase (putative) 21 46286337-46297751 Predicted intracellular proteins Evidence at protein level HPA016593, HPA018162 Uncertain Enhanced Nucleoplasm Breast cancer:5.54e-4 (favourable) Expressed in all Expressed in all testis: 92.0 Mixed +CLN8 C8orf61, EPMR, FLJ39417 ENSG00000182372 Ceroid-lipofuscinosis, neuronal 8 8 1755778-1801711 Disease related genes, Predicted membrane proteins Evidence at protein level Renal cancer:4.36e-8 (favourable) Expressed in all Mixed gallbladder: 7.5 Mixed +PLCXD1 FLJ11323 ENSG00000182378 Phosphatidylinositol specific phospholipase C X domain containing 1 X 276322-303356 Predicted intracellular proteins Evidence at protein level HPA007721 Approved Approved Cytosol Renal cancer:7.82e-14 (unfavourable), Head and neck cancer:2.50e-4 (favourable), Endometrial cancer:8.10e-4 (unfavourable) Expressed in all Expressed in all stomach: 25.8 Expressed in all +NXPH4 NPH4 ENSG00000182379 Neurexophilin 4 12 57216795-57226449 Predicted secreted proteins Evidence at transcript level Renal cancer:7.68e-6 (unfavourable), Liver cancer:2.57e-4 (unfavourable), Endometrial cancer:6.21e-4 (unfavourable), Glioma:8.20e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 8.3;prostate: 7.1;skin: 12.2 placenta: 3.8 Cell line enhanced AN3-CA: 71.1;RH-30: 60.3 +CACNB4 EJM4 ENSG00000182389 Calcium voltage-gated channel auxiliary subunit beta 4 2 151832768-152099475 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA015601 Approved Mixed Tissue enhanced cerebral cortex: 25.9 skin: 8.0 Cell line enhanced HMC-1: 17.7 +IFNL1 IL-29, IL29 ENSG00000182393 Interferon lambda 1 19 39296325-39298673 Predicted secreted proteins Evidence at protein level Not detected Not detected appendix,duodenum,lung,spleen,testis: 0.1 Not detected +TRAPPC6B ENSG00000182400 Trafficking protein particle complex 6B 14 39147811-39170532 Predicted intracellular proteins Evidence at protein level HPA047928 Uncertain Approved Endoplasmic reticulum Renal cancer:1.76e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 45.8 Expressed in all +PGBD4 FLJ32638, FLJ37497 ENSG00000182405 PiggyBac transposable element derived 4 15 34102073-34108684 Predicted intracellular proteins Evidence at protein level HPA040896, HPA059823 Uncertain Approved Nucleoplasm
Centrosome Mixed Mixed testis: 3.5 Mixed +CDY2A CDY2 ENSG00000182415 Chromodomain Y-linked 2A Y 18025787-18028597 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Group enriched 24 epididymis: 1.3;testis: 3.5 all non-specific tissues: 0.0 Not detected +NPLOC4 FLJ20657, KIAA1499, NPL4 ENSG00000182446 NPL4 homolog, ubiquitin recognition factor 17 81556887-81648465 Predicted intracellular proteins, Transporters Evidence at protein level HPA021560, HPA023295 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:6.95e-7 (unfavourable), Liver cancer:1.16e-5 (unfavourable) Expressed in all Expressed in all testis: 67.6 Expressed in all +OTOL1 C1QTNF15 ENSG00000182447 Otolin 1 3 161496808-161503942 Predicted secreted proteins No evidence HPA041030 Uncertain Not detected Not detected cerebral cortex: 0.8 Not detected +KCNK4 K2p4.1, TRAAK ENSG00000182450 Potassium two pore domain channel subfamily K member 4 11 64291302-64300031 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Not detected Tissue enriched 12 cerebral cortex: 4.3 cervix, uterine: 0.3 Not detected +TEX19 FLJ35767 ENSG00000182459 Testis expressed 19 17 82359247-82363776 Predicted intracellular proteins Evidence at protein level HPA054577 Enhanced Not detected Tissue enriched 266 testis: 27.2 cerebral cortex: 0.1 Cell line enhanced Daudi: 20.1;HMC-1: 20.0;MOLT-4: 16.0;U-266/70: 22.3 +TSHZ2 C20orf17, OVC10-2, TSH2, ZABC2, ZNF218 ENSG00000182463 Teashirt zinc finger homeobox 2 20 52972407-53495330 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038123 Uncertain Approved Nucleoplasm
Golgi apparatus Mixed Mixed ovary: 21.7 Cell line enhanced AN3-CA: 24.7;HeLa: 15.8;SiHa: 16.3;U-2197: 12.7 +CAPN12 ENSG00000182472 Calpain 12 19 38730187-38769904 Enzymes, Predicted intracellular proteins Evidence at protein level HPA053322 Approved Nucleoplasm
Focal adhesion sites Renal cancer:5.90e-6 (unfavourable) Mixed Group enriched 6 cervix, uterine: 7.3;gallbladder: 35.5 lung: 3.8 Cell line enriched 16 HMC-1: 34.3 +EXOC7 EXO70, Exo70p, KIAA1067, YJL085W ENSG00000182473 Exocyst complex component 7 17 76081017-76121576 Predicted intracellular proteins, Transporters Evidence at protein level HPA022840, HPA022842 Supported Approved Vesicles
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 102.7 Expressed in all +KPNA2 IPOA1, QIP2, RCH1, SRP1alpha ENSG00000182481 Karyopherin subunit alpha 2 17 68035519-68046842 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB015460, HPA041270 Enhanced Enhanced Nucleoplasm
Cytosol Renal cancer:1.26e-13 (unfavourable), Liver cancer:2.12e-10 (unfavourable), Urothelial cancer:2.19e-4 (unfavourable), Colorectal cancer:3.83e-4 (favourable), Lung cancer:5.77e-4 (unfavourable) Expressed in all Expressed in all testis: 349.5 Expressed in all +XKRX XKR2, XPLAC ENSG00000182489 XK related, X-linked X 100913445-100929433 Predicted membrane proteins, Transporters Evidence at transcript level Thyroid cancer:3.52e-4 (favourable) Mixed Tissue enhanced skin: 9.4 tonsil: 3.1 Cell line enriched 5 CACO-2: 6.8 +BGN DSPG1, SLRR1A ENSG00000182492 Biglycan X 153494939-153509554 Disease related genes, Predicted secreted proteins Evidence at protein level HPA003157, CAB003678 Enhanced Approved Endoplasmic reticulum
Golgi apparatus Renal cancer:6.00e-8 (unfavourable) Expressed in all Mixed gallbladder: 501.3 Cell line enhanced BJ: 258.4;BJ hTERT+: 318.9;fHDF/TERT166: 430.9;hTEC/SVTERT24-B: 230.0;HUVEC TERT2: 458.3;U-138 MG: 240.7 +CEP97 FLJ23047, LRRIQ2 ENSG00000182504 Centrosomal protein 97 3 101723925-101770562 Predicted intracellular proteins Evidence at protein level HPA002980 Enhanced Supported Microtubule organizing center
Cytosol Expressed in all Mixed testis: 13.4 Expressed in all +LHFPL1 ENSG00000182508 Lipoma HMGIC fusion partner-like 1 X 112630648-112680054 Predicted membrane proteins Evidence at transcript level HPA003029 Uncertain Mixed Tissue enhanced cerebral cortex: 1.8 seminal vesicle: 1.3 Cell line enhanced SK-MEL-30: 1.9 +FES FPS ENSG00000182511 FES proto-oncogene, tyrosine kinase 15 90883695-90895776 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001376 Approved Approved Nucleus
Vesicles
Cytosol Colorectal cancer:5.78e-4 (unfavourable) Expressed in all Expressed in all spleen: 96.5 Cell line enhanced HEL: 56.3;HL-60: 45.0;HMC-1: 100.9;NB-4: 46.6;THP-1: 73.8 +GLRX5 C14orf87, GRX5, PR01238 ENSG00000182512 Glutaredoxin 5 14 95533503-95544724 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042465, HPA063716 Approved Supported Mitochondria Renal cancer:7.83e-10 (favourable), Ovarian cancer:1.08e-5 (favourable) Expressed in all Expressed in all bone marrow: 56.6 Expressed in all +FAM104B CXorf44, FLJ20434 ENSG00000182518 Family with sequence similarity 104 member B X 55143102-55161310 Predicted intracellular proteins Evidence at transcript level HPA049082 Approved Lung cancer:1.22e-4 (favourable), Liver cancer:2.23e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 74.5 Expressed in all +TBPL2 TBP2, TRF3 ENSG00000182521 TATA-box binding protein like 2 14 55413541-55456726 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA056241 Uncertain Tissue enriched Mixed skin: 2.0 Cell line enhanced HDLM-2: 5.4;U-2 OS: 3.1;U-937: 3.1 +CAV3 LGMD1C, LQT9, VIP-21, VIP21 ENSG00000182533 Caveolin 3 3 8733800-8841808 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB017518, CAB018557, HPA054488 Enhanced Supported Vesicles
Plasma membrane Tissue enhanced Group enriched 6 heart muscle: 14.0;skeletal muscle: 63.3 esophagus: 6.0 Group enriched 15 LHCN-M2: 19.0;RH-30: 91.1 +MXRA7 FLJ46603, PS1TP1, TMAP1 ENSG00000182534 Matrix remodeling associated 7 17 76672551-76711016 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044819 Uncertain Approved Nucleus
Endoplasmic reticulum Urothelial cancer:1.80e-5 (unfavourable), Liver cancer:4.70e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 456.4 Cell line enhanced U-87 MG: 650.2 +LIMK2 ENSG00000182541 LIM domain kinase 2 22 31212239-31280080 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008183, CAB019313, HPA053882 Approved Supported Nucleoplasm
Cytosol Renal cancer:4.57e-6 (unfavourable) Expressed in all Expressed in all skin: 70.8 Expressed in all +MFSD5 MGC11308 ENSG00000182544 Major facilitator superfamily domain containing 5 12 53251251-53254405 Predicted membrane proteins Evidence at protein level HPA039773 Uncertain Liver cancer:1.43e-6 (unfavourable) Expressed in all Expressed in all skin: 49.6 Expressed in all +RNASE10 RAH1, RNASE9 ENSG00000182545 Ribonuclease A family member 10 (inactive) 14 20505537-20511169 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA052593 Uncertain Group enriched Mixed testis: 3.8 Cell line enhanced SiHa: 7.3;U-2 OS: 11.5 +ADI1 APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL ENSG00000182551 Acireductone dioxygenase 1 2 3497361-3519736 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035403, HPA035404 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all liver: 228.3 Expressed in all +RWDD4 FAM28A, MGC10198, RWDD4A ENSG00000182552 RWD domain containing 4 4 183639635-183659225 Predicted intracellular proteins Evidence at protein level HPA036501, HPA036502 Approved Approved Intermediate filaments Renal cancer:1.01e-6 (favourable) Expressed in all Expressed in all adrenal gland: 68.2 Expressed in all +SPNS3 MGC29671 ENSG00000182557 Sphingolipid transporter 3 (putative) 17 4433688-4488208 Predicted membrane proteins Evidence at protein level HPA023928 Uncertain Renal cancer:8.09e-4 (unfavourable) Mixed Tissue enriched 6 bone marrow: 12.4 spleen: 2.1 Group enriched 10 HL-60: 3.0;MOLT-4: 4.9;NB-4: 12.9;THP-1: 14.7;U-698: 3.6;U-937: 13.1 +CLEC4G LSECtin, UNQ431 ENSG00000182566 C-type lectin domain family 4 member G 19 7728957-7733906 Predicted membrane proteins Evidence at protein level CAB003789, HPA014044 Enhanced Mixed Group enriched 6 adipose tissue: 18.7;liver: 27.6;lymph node: 16.8 urinary bladder: 3.4 Not detected +SATB1 ENSG00000182568 SATB homeobox 1 3 18345387-18445588 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA051769, CAB056144 Supported Supported Nucleoplasm
Nuclear bodies Renal cancer:1.96e-7 (favourable), Pancreatic cancer:8.97e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 76.6 Cell line enhanced HDLM-2: 421.9;REH: 115.4;THP-1: 129.6 +NXPH3 NPH3 ENSG00000182575 Neurexophilin 3 17 49575858-49583827 Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 15.6 seminal vesicle: 9.6 Cell line enhanced BEWO: 14.1;BJ: 4.0 +CSF1R C-FMS, CD115, CSFR, FMS ENSG00000182578 Colony stimulating factor 1 receptor 5 150053291-150113372 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB008970, HPA012323 Uncertain Supported Vesicles
Plasma membrane Renal cancer:1.08e-4 (unfavourable), Testis cancer:4.92e-4 (unfavourable) Expressed in all Mixed spleen: 147.7 Group enriched 6 BEWO: 118.6;SK-BR-3: 35.4 +EPHB3 ETK2, Hek2, Tyro6 ENSG00000182580 EPH receptor B3 3 184561784-184582409 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level HPA007698, HPA008184, CAB034350 Enhanced Renal cancer:7.88e-5 (unfavourable) Expressed in all Tissue enhanced skin: 45.4 stomach: 18.1 Cell line enhanced BEWO: 27.9;HaCaT: 35.7;SK-BR-3: 23.1;T-47d: 19.3 +VCX VCX-10r, VCX-B1, VCX1, VCX10R ENSG00000182583 Variable charge, X-linked X 7842262-7844143 Predicted intracellular proteins Evidence at protein level HPA044996, HPA049357 Supported Mixed Tissue enriched 159 testis: 39.1 duodenum: 0.2 Cell line enhanced NB-4: 1.0;U-138 MG: 1.4;U-266/70: 2.2 +ACTL10 C20orf134 ENSG00000182584 Actin like 10 20 33666498-33668525 Predicted secreted proteins Evidence at transcript level Mixed Tissue enriched 15 testis: 22.1 prostate: 1.4 Cell line enhanced RPMI-8226: 3.3;SiHa: 3.6 +EPGN ALGV3072, EPG, epigen, PRO9904 ENSG00000182585 Epithelial mitogen 4 74308473-74315307 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014369 Approved Nucleus
Nuclear membrane
Cytosol Urothelial cancer:2.40e-4 (unfavourable) Tissue enhanced Tissue enriched 12 esophagus: 63.6 seminal vesicle: 5.4 Group enriched 7 hTCEpi: 132.6;U-2197: 76.6 +KRTAP11-1 KAP11.1 ENSG00000182591 Keratin associated protein 11-1 21 30880644-30881555 Predicted intracellular proteins Evidence at protein level HPA054008 Supported Group enriched Not detected skin: 0.1 Not detected +C2orf82 ASCL830, UNQ830 ENSG00000182600 Chromosome 2 open reading frame 82 2 232857270-232878708 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA052824 Uncertain Approved Nucleus
Nucleoli Endometrial cancer:3.56e-4 (unfavourable) Mixed Tissue enhanced breast: 5.1;testis: 4.1 cerebral cortex: 2.6 Cell line enriched 13 Hep G2: 40.1 +HS3ST4 3OST4 ENSG00000182601 Heparan sulfate-glucosamine 3-sulfotransferase 4 16 25692026-26137688 Enzymes, Predicted membrane proteins Evidence at transcript level Mixed Tissue enriched 7 cerebral cortex: 18.7 breast: 2.8 Cell line enhanced NTERA-2: 1.4 +TRAK1 KIAA1042, MILT1, OIP106 ENSG00000182606 Trafficking kinesin protein 1 3 42013802-42225889 Predicted intracellular proteins Evidence at protein level HPA005853, HPA011367 Approved Approved Nucleoplasm
Endoplasmic reticulum Renal cancer:4.84e-8 (favourable) Expressed in all Expressed in all heart muscle: 110.1 Expressed in all +TSPAN10 OCSP ENSG00000182612 Tetraspanin 10 17 81637171-81648749 Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enhanced skin: 1.5 lymph node: 1.0 Cell line enhanced SK-MEL-30: 13.4;U-87 MG: 7.4 +OR2V2 OR2V3, OST713 ENSG00000182613 Olfactory receptor family 2 subfamily V member 2 5 181154943-181155890 G-protein coupled receptors, Predicted membrane proteins No evidence HPA049953 Uncertain Not detected Not detected fallopian tube: 0.4 Not detected +PLCB1 KIAA0581, PLC-I, PLC154 ENSG00000182621 Phospholipase C beta 1 20 8077251-8968360 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004275, CAB005334, HPA034743, HPA057910 Enhanced Approved Plasma membrane Mixed Tissue enhanced cerebral cortex: 68.3;parathyroid gland: 121.3 placenta: 28.2 Cell line enhanced Hep G2: 46.8 +SKA2 FAM33A, FLJ12758 ENSG00000182628 Spindle and kinetochore associated complex subunit 2 17 59109951-59155269 Predicted intracellular proteins Evidence at protein level HPA059235 Uncertain Renal cancer:2.90e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 43.1 Expressed in all +RXFP3 GPCR135, RLN3R1, RXFPR3, SALPR ENSG00000182631 Relaxin/insulin like family peptide receptor 3 5 33936386-33938237 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA027833 Uncertain Not detected Not detected adrenal gland: 0.3 Not detected +OR10G7 ENSG00000182634 Olfactory receptor family 10 subfamily G member 7 11 124038066-124039010 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +NDN HsT16328, PWCR ENSG00000182636 Necdin, MAGE family member 15 23685400-23687330 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA074457 Approved Nucleoplasm
Cytosol Renal cancer:4.52e-4 (unfavourable) Expressed in all Mixed ovary: 85.0 Cell line enhanced AF22: 53.6;HSkMC: 51.0;NTERA-2: 43.3;U-2 OS: 83.1 +CCDC172 C10orf96, MGC35062 ENSG00000182645 Coiled-coil domain containing 172 10 116324428-116380029 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 14 testis: 22.0 prostate: 1.5 Cell line enriched 177 NTERA-2: 30.9 +OR4Q3 C14orf13, OR4Q4 ENSG00000182652 Olfactory receptor family 4 subfamily Q member 3 14 19747428-19748369 G-protein coupled receptors, Predicted membrane proteins No evidence HPA049924 Uncertain Not detected Not detected testis: 0.1 Not detected +NTM HNT, IGLON2, NTRI ENSG00000182667 Neurotrimin 11 131370478-132336822 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB024875 Enhanced Renal cancer:1.10e-8 (unfavourable) Mixed Tissue enhanced cerebral cortex: 116.0 lung: 39.1 Cell line enhanced LHCN-M2: 102.1;U-2 OS: 86.6;WM-115: 164.5 +TTC3 DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII ENSG00000182670 Tetratricopeptide repeat domain 3 21 37073226-37203112 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016810, HPA023964, HPA036304 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all thyroid gland: 108.0 Expressed in all +KCNB2 Kv2.2 ENSG00000182674 Potassium voltage-gated channel subfamily B member 2 8 72537391-72938349 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA065970 Approved Nucleoli
Plasma membrane
Midbody Not detected Tissue enhanced cerebral cortex: 3.2;spleen: 3.3 fallopian tube,testis: 0.7 Cell line enhanced HaCaT: 1.3;HDLM-2: 1.4;HEK 293: 3.2;SCLC-21H: 3.4 +PPP1R27 DYSFIP1, toonin ENSG00000182676 Protein phosphatase 1 regulatory subunit 27 17 81833492-81835050 Predicted intracellular proteins Evidence at protein level HPA048632 Uncertain Tissue enriched Tissue enriched 38 skeletal muscle: 170.9 prostate: 4.5 Group enriched 26 HL-60: 317.1;THP-1: 513.1 +BRICD5 C16orf79, MGC21830 ENSG00000182685 BRICHOS domain containing 5 16 2209253-2211950 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019197, HPA063522 Uncertain Approved Nucleoplasm
Actin filaments Urothelial cancer:8.06e-5 (favourable), Pancreatic cancer:7.01e-4 (favourable), Breast cancer:9.74e-4 (favourable) Expressed in all Mixed testis: 10.6 Mixed +GALR2 GALNR2 ENSG00000182687 Galanin receptor 2 17 76074794-76077541 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA044513 Approved Mixed Tissue enhanced smooth muscle: 2.4 bone marrow: 0.6 Cell line enhanced NTERA-2: 2.0;THP-1: 2.0 +RESP18 ENSG00000182698 Regulated endocrine specific protein 18 2 219327409-219333177 Predicted intracellular proteins Evidence at transcript level HPA045849 Uncertain Not detected Tissue enhanced cerebral cortex: 2.1 testis: 0.7 Not detected +IGIP C5orf53, LOC492311 ENSG00000182700 IgA inducing protein 5 140125935-140129392 Predicted secreted proteins Evidence at transcript level HPA041877, HPA048615 Approved Approved Vesicles Renal cancer:6.25e-6 (favourable), Pancreatic cancer:3.94e-4 (favourable) Expressed in all Mixed parathyroid gland: 28.6 Mixed +TSKU E2IG4, LRRC54, TSK ENSG00000182704 Tsukushi, small leucine rich proteoglycan 11 76782251-76798154 Predicted secreted proteins Evidence at protein level HPA008164 Approved Approved Nucleus
Nuclear bodies Renal cancer:2.80e-8 (unfavourable), Prostate cancer:1.66e-4 (favourable), Pancreatic cancer:2.87e-4 (unfavourable), Endometrial cancer:3.66e-4 (favourable) Expressed in all Expressed in all liver: 114.4 Cell line enhanced A549: 150.8;ASC diff: 186.5 +CMC4 MTCP1, MTCP1NB, p8, P8MTCP1 ENSG00000182712 C-X9-C motif containing 4 X 155061622-155071362 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045866 Approved Supported Mitochondria Not detected Expressed in all heart muscle: 21.4 Expressed in all +ANXA2 ANX2, ANX2L4, CAL1H, LIP2, LPC2D ENSG00000182718 Annexin A2 15 60347134-60402883 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004311, HPA046964, HPA061798 Enhanced Renal cancer:2.11e-6 (unfavourable), Pancreatic cancer:8.47e-6 (unfavourable), Liver cancer:2.54e-5 (unfavourable), Urothelial cancer:6.59e-5 (unfavourable), Endometrial cancer:6.88e-5 (favourable), Lung cancer:7.51e-4 (unfavourable) Expressed in all Expressed in all esophagus: 1488.4 Expressed in all +RGS6 ENSG00000182732 Regulator of G-protein signaling 6 14 71932439-72566529 Predicted intracellular proteins Evidence at protein level HPA003067 Uncertain Group enriched Tissue enhanced cerebral cortex: 17.5;testis: 18.7 thyroid gland: 8.8 Group enriched 8 HEL: 10.1;Karpas-707: 24.7 +HOXB4 HOX2, HOX2F ENSG00000182742 Homeobox B4 17 48575513-48580111 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057432 Uncertain Supported Nucleus
Centrosome Ovarian cancer:2.23e-4 (unfavourable) Mixed Tissue enhanced epididymis: 16.1 fallopian tube: 12.5 Cell line enhanced EFO-21: 30.9;HMC-1: 17.8 +SLC35D3 FRCL1 ENSG00000182747 Solute carrier family 35 member D3 6 136922264-136925639 Predicted membrane proteins, Transporters Evidence at protein level HPA030431, HPA067497 Uncertain Approved Microtubule organizing center Tissue enhanced Tissue enhanced adrenal gland: 1.2 lung,stomach: 0.6 Group enriched 16 SCLC-21H: 4.2;SH-SY5Y: 16.3 +PAQR7 MPRA, mSR ENSG00000182749 Progestin and adipoQ receptor family member 7 1 25861210-25871253 Predicted membrane proteins Evidence at protein level HPA046936 Approved Approved Cytosol Renal cancer:1.05e-5 (favourable), Liver cancer:1.14e-4 (unfavourable) Expressed in all Mixed testis: 51.0 Cell line enhanced CAPAN-2: 54.0 +PAPPA ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1 ENSG00000182752 Pappalysin 1 9 116153804-116402322 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001667, CAB016724 Enhanced Uncertain Plasma membrane
Cytosol Mixed Tissue enriched 7 placenta: 104.5 parathyroid gland: 14.8 Cell line enhanced ASC diff: 34.3;HSkMC: 99.9;U-138 MG: 35.8 +MAFA hMafA, RIPE3b1 ENSG00000182759 MAF bZIP transcription factor A 8 143419182-143430406 Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Group enriched 11 skeletal muscle: 8.6;testis: 2.5 placenta: 0.5 Cell line enhanced MCF7: 1.7;SCLC-21H: 3.7;T-47d: 2.8;U-2 OS: 2.1 +NGRN DSC92 ENSG00000182768 Neugrin, neurite outgrowth associated 15 90265659-90278141 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041367 Approved Expressed in all Mixed thyroid gland: 7.1 Expressed in all +GRID1 GluD1, KIAA1220 ENSG00000182771 Glutamate ionotropic receptor delta type subunit 1 10 85599555-86366493 Predicted membrane proteins Evidence at protein level Group enriched Tissue enhanced cerebral cortex: 7.7 thyroid gland: 3.4 Cell line enhanced Daudi: 1.8;HEL: 2.3;SH-SY5Y: 1.0 +RPS17 MGC72007, RPS17L, RPS17L1, RPS17L2, S17 ENSG00000182774 Ribosomal protein S17 15 82536753-82540564 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055060 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:1.78e-4 (unfavourable) Expressed in all Expressed in all ovary: 1572.3 Expressed in all +HCAR2 GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG ENSG00000182782 Hydroxycarboxylic acid receptor 2 12 122701293-122703343 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA028660 Approved Approved Cell Junctions Group enriched Tissue enhanced spleen: 36.0 esophagus: 25.5 Cell line enriched 7 HaCaT: 105.3 +OR2T29 ENSG00000182783 Olfactory receptor family 2 subfamily T member 29 1 248558544-248559491 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +CCDC87 FLJ10786 ENSG00000182791 Coiled-coil domain containing 87 11 66590176-66593083 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 7 testis: 18.3 parathyroid gland: 2.5 Cell line enhanced SCLC-21H: 2.7 +GSTA5 ENSG00000182793 Glutathione S-transferase alpha 5 6 52831655-52846095 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004342, HPA048934, HPA053817 Uncertain Approved Cytosol Not detected Not detected testis: 0.1 Not detected +C1orf116 FLJ36507, MGC2742, MGC4309, SARG ENSG00000182795 Chromosome 1 open reading frame 116 1 207018521-207032756 Predicted intracellular proteins Evidence at protein level HPA011888, HPA011889 Enhanced Supported Plasma membrane
Cytosol Renal cancer:1.01e-5 (favourable) Mixed Tissue enhanced esophagus: 112.4;lung: 109.2;prostate: 82.0 stomach: 54.9 Group enriched 5 A-431: 50.3;CAPAN-2: 87.3;HaCaT: 108.7;HBEC3-KT: 85.0;hTCEpi: 44.4;hTERT-HME1: 26.3;RPTEC TERT1: 42.8 +MAGEB17 ENSG00000182798 MAGE family member B17 X 16167481-16171464 Predicted intracellular proteins Evidence at transcript level HPA003756 Uncertain Mixed Tissue enriched 6 testis: 2.9 epididymis: 0.4 Cell line enhanced U-138 MG: 2.7;U-2 OS: 6.2;U-266/70: 11.3 +CRIP2 CRP2, ESP1 ENSG00000182809 Cysteine rich protein 2 14 105472962-105480170 Predicted intracellular proteins Evidence at protein level HPA042664 Approved Approved Nucleus
Nucleoli
Plasma membrane Expressed in all Tissue enhanced heart muscle: 315.6 fallopian tube: 115.7 Cell line enhanced MCF7: 206.8 +DDX28 FLJ11282, MDDX28 ENSG00000182810 DEAD-box helicase 28 16 68021274-68023442 Enzymes, Predicted secreted proteins Evidence at protein level HPA041911, HPA053585 Approved Supported Nucleoli
Mitochondria
Cytosol Renal cancer:2.07e-10 (favourable) Expressed in all Expressed in all bone marrow: 11.2 Expressed in all +KRTAP13-2 KAP13-2 ENSG00000182816 Keratin associated protein 13-2 21 30371391-30372257 Plasma proteins, Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 20 colon: 1.9;rectum: 2.0 all non-specific tissues: 0.0 Not detected +ACBD3 GCP60, GOCAP1, GOLPH1, PAP7 ENSG00000182827 Acyl-CoA binding domain containing 3 1 226144679-226186730 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015594 Uncertain Supported Golgi apparatus Expressed in all Expressed in all thyroid gland: 48.5 Expressed in all +C16orf72 FLJ41272, PRO0149 ENSG00000182831 Chromosome 16 open reading frame 72 16 9091648-9121640 Predicted intracellular proteins Evidence at protein level HPA041568, HPA067492 Uncertain Approved Nucleoplasm
Vesicles Head and neck cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 67.5 Expressed in all +PLCXD3 ENSG00000182836 Phosphatidylinositol specific phospholipase C X domain containing 3 5 41306954-41510628 Predicted intracellular proteins Evidence at protein level HPA046849 Uncertain Approved Golgi apparatus Mixed Tissue enhanced adrenal gland: 16.7;heart muscle: 22.0;ovary: 28.4 cerebral cortex: 8.3 Cell line enhanced BJ hTERT+: 6.9;PC-3: 6.9;SH-SY5Y: 36.5;TIME: 15.0 +VMO1 ENSG00000182853 Vitelline membrane outer layer 1 homolog 17 4785285-4786433 Predicted secreted proteins Evidence at protein level HPA023038 Uncertain Renal cancer:1.34e-6 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 34.4 spleen: 14.6 Cell line enhanced A549: 2.7;MCF7: 3.0 +OR4F15 ENSG00000182854 Olfactory receptor family 4 subfamily F member 15 15 101818163-101819147 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ALG12 CDG1G, ECM39 ENSG00000182858 ALG12, alpha-1,6-mannosyltransferase 22 49900229-49918458 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA003076, HPA051665 Approved Approved Endoplasmic reticulum Renal cancer:3.60e-5 (favourable), Endometrial cancer:6.09e-4 (favourable) Expressed in all Expressed in all thyroid gland: 17.2 Expressed in all +LCK ENSG00000182866 LCK proto-oncogene, Src family tyrosine kinase 1 32251239-32286165 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA003494, CAB003816 Enhanced Approved Golgi apparatus Endometrial cancer:2.96e-6 (favourable), Renal cancer:2.60e-5 (unfavourable), Melanoma:5.65e-5 (favourable), Head and neck cancer:2.91e-4 (favourable) Mixed Tissue enhanced lymph node: 125.9;tonsil: 72.4 appendix: 66.3 Group enriched 7 MOLT-4: 429.5;U-698: 207.6 +GALNT9 GALNAC-T9 ENSG00000182870 Polypeptide N-acetylgalactosaminyltransferase 9 12 132196372-132329349 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA075016 Approved Vesicles Mixed Tissue enhanced cerebral cortex: 29.4 thyroid gland: 6.3 Cell line enriched 6 U-87 MG: 30.6 +COL18A1 KNO, KNO1, KS ENSG00000182871 Collagen type XVIII alpha 1 chain 21 45405137-45513720 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB001961, HPA011025, HPA036104 Approved Approved Golgi apparatus Liver cancer:6.16e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 144.0 Cell line enhanced EFO-21: 290.7;NTERA-2: 173.6;TIME: 152.4 +RBM10 DXS8237E, GPATC9, GPATCH9, KIAA0122, ZRANB5 ENSG00000182872 RNA binding motif protein 10 X 47144869-47186813 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034972, HPA057372 Approved Enhanced Nuclear speckles Pancreatic cancer:2.86e-6 (favourable), Cervical cancer:6.71e-4 (favourable) Expressed in all Expressed in all ovary: 35.1 Expressed in all +ADGRG3 GPR97, Pb99, PGR26 ENSG00000182885 Adhesion G protein-coupled receptor G3 16 57668187-57689378 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA040469 Uncertain Mixed Group enriched 5 appendix: 19.0;bone marrow: 86.6 adipose tissue: 9.8 Cell line enhanced NB-4: 2.5;SK-MEL-30: 1.6 +GLUD2 GLUDP1 ENSG00000182890 Glutamate dehydrogenase 2 X 121047588-121050080 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042492, HPA044839, HPA061369 Uncertain Supported Mitochondria Renal cancer:1.98e-4 (favourable) Mixed Tissue enriched 11 testis: 46.5 epididymis: 4.1 Cell line enhanced HAP1: 7.6;K-562: 7.6;SK-MEL-30: 8.3;WM-115: 11.7 +TMEM95 MGC129793, UNQ9390 ENSG00000182896 Transmembrane protein 95 17 7355123-7357219 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 48 testis: 9.9 gallbladder: 0.2 Not detected +TCHHL1 S100A17, THHL1 ENSG00000182898 Trichohyalin like 1 1 152084144-152089064 Predicted intracellular proteins Evidence at protein level HPA042579, HPA063483 Enhanced Approved Nuclear membrane
Nucleoli Not detected Not detected epididymis: 0.1 Cell line enriched 37 SK-BR-3: 3.7 +RPL35A L35A ENSG00000182899 Ribosomal protein L35a 3 197949987-197956610 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Renal cancer:1.37e-6 (unfavourable), Pancreatic cancer:4.43e-4 (unfavourable), Liver cancer:9.89e-4 (unfavourable) Expressed in all Expressed in all ovary: 2041.8 Expressed in all +RGS7 ENSG00000182901 Regulator of G-protein signaling 7 1 240775515-241357230 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017561 Enhanced Enhanced Cytosol Tissue enhanced Group enriched 8 adrenal gland: 10.7;cerebral cortex: 46.4;testis: 10.9 stomach: 2.9 Cell line enhanced U-2 OS: 6.8 +SLC25A18 ENSG00000182902 Solute carrier family 25 member 18 22 17563439-17590994 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Group enriched Tissue enhanced cerebral cortex: 74.5;liver: 25.2 adipose tissue: 13.8 Cell line enhanced BEWO: 8.2 +ZNF721 KIAA1982 ENSG00000182903 Zinc finger protein 721 4 425815-499156 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA065313 Approved Microtubule organizing center
Cytosol Urothelial cancer:2.76e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 30.8 Expressed in all +TCEAL7 MGC23947, WEX5 ENSG00000182916 Transcription elongation factor A like 7 X 103330196-103332326 Predicted intracellular proteins Evidence at protein level HPA051507, HPA065080 Enhanced Supported Nucleus Stomach cancer:3.53e-4 (unfavourable), Renal cancer:4.31e-4 (unfavourable) Tissue enriched Tissue enhanced cerebral cortex: 145.6 endometrium: 76.7 Cell line enhanced hTEC/SVTERT24-B: 81.8;SCLC-21H: 242.8 +C11orf54 PTD012 ENSG00000182919 Chromosome 11 open reading frame 54 11 93741591-93764749 Predicted intracellular proteins Evidence at protein level HPA040088, HPA040511 Approved Approved Nucleoplasm
Nuclear bodies Renal cancer:5.06e-6 (favourable) Expressed in all Expressed in all kidney: 539.3 Expressed in all +CEP63 FLJ13386 ENSG00000182923 Centrosomal protein 63 3 134485743-134575017 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA058154, HPA058313 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 83.9 Expressed in all +WFDC10B WAP12 ENSG00000182931 WAP four-disulfide core domain 10B 20 45684653-45705019 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enriched 12 epididymis: 33.3 testis: 2.7 Cell line enhanced PC-3: 1.8 +SRPRA SR-alpha, Sralpha, SRP-alpha, SRPR ENSG00000182934 SRP receptor alpha subunit 11 126262919-126269144 Plasma proteins, Predicted intracellular proteins Evidence at protein level Endometrial cancer:8.56e-4 (favourable) Expressed in all Expressed in all epididymis: 170.3 Expressed in all +OTOP3 ENSG00000182938 Otopetrin 3 17 74935719-74949992 Predicted membrane proteins Evidence at protein level Head and neck cancer:3.86e-4 (favourable) Tissue enhanced Not detected small intestine: 0.5 Not detected +EWSR1 EWS ENSG00000182944 EWS RNA binding protein 1 22 29268009-29300525 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004230, HPA051771, HPA062953 Enhanced Enhanced Nucleus
Nucleoli Liver cancer:1.27e-6 (unfavourable), Renal cancer:1.21e-5 (unfavourable) Expressed in all Expressed in all testis: 213.6 Expressed in all +ODF3L1 MGC48986 ENSG00000182950 Outer dense fiber of sperm tails 3 like 1 15 75723977-75727688 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 6 testis: 24.0 gallbladder: 3.9 Cell line enhanced U-87 MG: 1.2 +HMGN4 HMG17L3, NHC ENSG00000182952 High mobility group nucleosomal binding domain 4 6 26538405-26546254 Predicted intracellular proteins Evidence at protein level HPA077364 Uncertain Nucleus Expressed in all Expressed in all thyroid gland: 131.8 Expressed in all +SPATA13 ARHGEF29, FLJ31208 ENSG00000182957 Spermatogenesis associated 13 13 23979805-24307074 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040185, HPA041208 Approved Supported Nucleoplasm
Cytosol Urothelial cancer:1.16e-4 (favourable) Expressed in all Tissue enhanced spleen: 90.2 lymph node: 27.2 Cell line enhanced HDLM-2: 43.0 +GJC1 CX45, GJA7 ENSG00000182963 Gap junction protein gamma 1 17 44798448-44830816 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA071788 Uncertain Nucleoli
Cell Junctions
Cytosol Renal cancer:3.55e-8 (unfavourable), Urothelial cancer:7.83e-4 (unfavourable) Expressed in all Tissue enhanced endometrium: 44.3;placenta: 51.5;smooth muscle: 49.2 seminal vesicle: 27.2 Mixed +SOX1 ENSG00000182968 SRY-box 1 13 112067647-112070488 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Group enriched Group enriched 8 cerebral cortex: 3.6;testis: 1.5 skin: 0.3 Group enriched 6 AF22: 44.0;SCLC-21H: 10.1 +CNOT10 FLJ12890, FLJ13165 ENSG00000182973 CCR4-NOT transcription complex subunit 10 3 32685145-32773875 Predicted intracellular proteins Evidence at protein level HPA035614, HPA041450 Approved Approved Nucleoplasm
Centrosome
Cytosol Liver cancer:1.03e-6 (unfavourable) Expressed in all Expressed in all testis: 72.1 Expressed in all +RP11-294C11.1 ENSG00000182974 15 21637909-21638992 Predicted membrane proteins Evidence at transcript level HPA058889 Uncertain Not detected Tissue enriched 24 testis: 2.3 all non-specific tissues: 0.0 Not detected +MTA1 ENSG00000182979 Metastasis associated 1 14 105419820-105470729 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004508, HPA005544 Supported Enhanced Nucleoplasm
Cytosol Pancreatic cancer:9.48e-5 (favourable), Liver cancer:4.62e-4 (unfavourable) Expressed in all Expressed in all testis: 35.8 Expressed in all +ZNF662 FLJ45880 ENSG00000182983 Zinc finger protein 662 3 42905731-42917641 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA039116, HPA040377 Uncertain Mixed Mixed skin: 13.3 Cell line enhanced SH-SY5Y: 3.6;U-2 OS: 4.9 +CADM1 BL2, IGSF4, IGSF4A, Necl-2, NECL2, RA175, ST17, SYNCAM, SYNCAM1, TSLC1 ENSG00000182985 Cell adhesion molecule 1 11 115169218-115504957 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB037266 Enhanced Supported Cell Junctions Endometrial cancer:1.32e-4 (favourable) Expressed in all Mixed parathyroid gland: 151.6 Cell line enhanced CACO-2: 245.0;WM-115: 185.3 +ZNF320 DKFZp686G16228, ZFPL ENSG00000182986 Zinc finger protein 320 19 52863790-52897693 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043696, HPA062474 Uncertain Approved Nucleoplasm
Cytoplasmic bodies Expressed in all Mixed parathyroid gland: 22.5 Cell line enhanced RT4: 70.3 +C12orf60 MGC47869 ENSG00000182993 Chromosome 12 open reading frame 60 12 14803572-14906586 Predicted intracellular proteins Evidence at protein level HPA043911 Approved Nucleus
Cytosol Mixed Group enriched 6 adrenal gland: 5.9;testis: 23.9 kidney: 2.5 Mixed +PYCR1 P5C ENSG00000183010 Pyrroline-5-carboxylate reductase 1 17 81932384-81942412 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA047660 Approved Renal cancer:7.33e-12 (unfavourable), Liver cancer:2.33e-4 (unfavourable) Expressed in all Mixed salivary gland: 52.3 Mixed +NAA38 LSMD1, MGC14151, PFAAP2 ENSG00000183011 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 17 7856685-7885238 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059189 Supported Nucleus Expressed in all Expressed in all testis: 78.3 Expressed in all +SPNS2 ENSG00000183018 Sphingolipid transporter 2 17 4498838-4539035 Predicted membrane proteins, Transporters Evidence at protein level HPA068717 Uncertain Expressed in all Tissue enhanced esophagus: 46.4 kidney: 30.0 Group enriched 6 BEWO: 29.2;RPTEC TERT1: 120.6;SK-BR-3: 55.8 +MCEMP1 C19orf59, MGC132456 ENSG00000183019 Mast cell expressed membrane protein 1 19 7676628-7679826 Predicted membrane proteins Evidence at protein level HPA014731 Enhanced Mixed Group enriched 9 appendix: 27.9;bone marrow: 43.9;lung: 110.4 smooth muscle: 7.0 Group enriched 5 THP-1: 36.2;U-937: 130.3 +AP2A2 ADTAB, CLAPA2, DKFZP564D1864, HIP9, HYPJ, KIAA0899 ENSG00000183020 Adaptor related protein complex 2 alpha 2 subunit 11 924894-1012245 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017514, HPA043040 Enhanced Supported Nucleoplasm
Vesicles Liver cancer:9.27e-5 (unfavourable), Pancreatic cancer:4.57e-4 (favourable) Expressed in all Mixed spleen: 16.0 Mixed +SLC8A1 NCX1 ENSG00000183023 Solute carrier family 8 member A1 2 40097270-40611053 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB022694, HPA070007 Uncertain Supported Nucleoplasm
Plasma membrane Mixed Tissue enhanced heart muscle: 78.0 seminal vesicle: 37.6 Cell line enhanced BJ: 24.4;fHDF/TERT166: 54.5 +OR1G1 OR17-209, OR1G2 ENSG00000183024 Olfactory receptor family 1 subfamily G member 1 17 3126584-3127581 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.2 Not detected +SLC25A21 ODC, ODC1 ENSG00000183032 Solute carrier family 25 member 21 14 36678431-37172866 Predicted intracellular proteins, Transporters Evidence at protein level HPA000662 Uncertain Not detected Tissue enhanced testis: 7.6 bone marrow: 3.8 Group enriched 6 HEK 293: 8.7;K-562: 23.4;Karpas-707: 39.1 +OTOP2 ENSG00000183034 Otopetrin 2 17 74924275-74933912 Predicted membrane proteins Evidence at transcript level HPA024524, HPA053090 Uncertain Not detected Tissue enhanced colon: 20.0;rectum: 11.4 testis: 3.9 Cell line enriched 50 HDLM-2: 9.6 +CYLC1 ENSG00000183035 Cylicin 1 X 83861126-83886699 Predicted intracellular proteins Evidence at protein level HPA070355 Enhanced Not detected Tissue enriched 429 testis: 42.9 all non-specific tissues: 0.0 Not detected +PCP4 PEP-19 ENSG00000183036 Purkinje cell protein 4 21 39867317-39929397 Predicted intracellular proteins Evidence at protein level HPA005792 Enhanced Supported Approved Nucleus
Nucleoli
Cytosol Renal cancer:1.85e-7 (favourable), Cervical cancer:9.76e-4 (favourable) Mixed Tissue enhanced seminal vesicle: 1209.1 prostate: 369.5 Cell line enhanced RPMI-8226: 108.9;SK-BR-3: 19.1;T-47d: 44.5 +ABAT GABAT ENSG00000183044 4-aminobutyrate aminotransferase 16 8674565-8784575 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041528, HPA041690 Enhanced Supported Supported Mitochondria Renal cancer:5.44e-8 (favourable), Liver cancer:5.36e-5 (favourable), Lung cancer:5.93e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 164.5;kidney: 135.3;liver: 175.2 thyroid gland: 47.5 Cell line enhanced Hep G2: 83.0;MCF7: 60.0;RH-30: 64.1;T-47d: 39.1 +SLC25A10 DIC ENSG00000183048 Solute carrier family 25 member 10 17 81712236-81721016 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA023048 Supported Supported Nucleoplasm
Mitochondria Urothelial cancer:1.31e-4 (favourable), Head and neck cancer:2.56e-4 (favourable), Ovarian cancer:8.14e-4 (favourable) Expressed in all Mixed kidney: 35.4 Expressed in all +CAMK1D CKLiK ENSG00000183049 Calcium/calmodulin dependent protein kinase ID 10 12349482-12835545 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA007266 Enhanced Approved Nucleus
Cytosol Lung cancer:1.67e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 52.0 skin,thyroid gland: 21.9 Cell line enhanced HDLM-2: 105.6;U-266/70: 38.2 +RGPD6 RGP6 ENSG00000183054 RANBP2-like and GRIP domain containing 6 2 110513812-110577185 Predicted intracellular proteins Evidence at protein level HPA045704, HPA049497, HPA051675, HPA067564 Uncertain Uncertain Nuclear membrane
Vesicles Not detected Expressed in all testis: 83.3 Mixed +LYSMD4 FLJ33008 ENSG00000183060 LysM domain containing 4 15 99715697-99733561 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA029152, HPA059824 Approved Approved Actin filaments
Cytosol Expressed in all Mixed skin: 18.3 Mixed +WBP2NL FLJ26145, GRAMD7, MGC26816, PAWP ENSG00000183066 WBP2 N-terminal like 22 41998725-42058456 Predicted intracellular proteins Evidence at protein level HPA048557 Enhanced Not detected Tissue enriched 8 testis: 11.7 epididymis: 1.5 Not detected +IGSF5 JAM4 ENSG00000183067 Immunoglobulin superfamily member 5 21 39745407-39802096 Predicted membrane proteins Evidence at transcript level HPA057282 Uncertain Tissue enhanced Mixed placenta: 3.6 Cell line enhanced T-47d: 5.4 +NKX2-5 CSX, CSX1, NKX2.5, NKX2E, NKX4-1 ENSG00000183072 NK2 homeobox 5 5 173232109-173235357 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA065034 Approved Nucleoplasm
Cytosol Mixed Group enriched 126 heart muscle: 32.7;spleen: 14.5 breast,placenta,urinary bladder: 0.1 Cell line enhanced HEK 293: 27.1;NTERA-2: 10.7;U-2 OS: 24.8;U-251 MG: 15.4 +AFMID DKFZp686F03259, KF ENSG00000183077 Arylformamidase 17 78187317-78207701 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023861, HPA026536 Uncertain Approved Mitochondria Expressed in all Expressed in all kidney: 87.5 Expressed in all +GAS6 AXLLG, AXSF, DKFZp666G247, FLJ34709 ENSG00000183087 Growth arrest specific 6 13 113820549-113864067 Predicted secreted proteins Evidence at protein level HPA008275, HPA056080 Approved Approved Microtubule organizing center
Cytosol Urothelial cancer:8.93e-6 (unfavourable) Expressed in all Expressed in all fallopian tube: 193.7 Cell line enhanced BJ: 295.0;BJ hTERT+: 407.1;RPMI-8226: 339.8 +FREM3 ENSG00000183090 FRAS1 related extracellular matrix 3 4 143577302-143700675 Predicted secreted proteins Evidence at protein level HPA041641 Uncertain Not detected Tissue enhanced cerebral cortex: 1.6 lung: 0.6 Not detected +NEB NEB177D, NEM2 ENSG00000183091 Nebulin 2 151485336-151734487 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016601 Enhanced Tissue enhanced Tissue enriched 97 skeletal muscle: 3273.5 prostate: 33.7 Cell line enhanced RH-30: 33.2;U-266/70: 9.8 +BEGAIN KIAA1446 ENSG00000183092 Brain enriched guanylate kinase associated 14 100537147-100587413 Predicted intracellular proteins Evidence at protein level HPA002899 Uncertain Uncertain Nucleus
Golgi apparatus
Cytosol Mixed Tissue enriched 5 cerebral cortex: 20.0 adrenal gland: 3.8 Group enriched 8 HeLa: 36.4;SH-SY5Y: 137.4 +GPC6 ENSG00000183098 Glypican 6 13 93226842-94407401 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017671 Approved Approved Golgi apparatus
Vesicles Expressed in all Mixed gallbladder: 27.3 Cell line enhanced ASC diff: 42.9;HSkMC: 51.5;U-87 MG: 51.7 +ARHGEF37 FLJ41603 ENSG00000183111 Rho guanine nucleotide exchange factor 37 5 149551947-149634968 Predicted intracellular proteins Evidence at protein level HPA043885, HPA053487 Uncertain Approved Cytosol Renal cancer:6.85e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 68.3 Cell line enhanced EFO-21: 13.0;HaCaT: 22.9;hTCEpi: 24.4 +FAM43B FLJ44952 ENSG00000183114 Family with sequence similarity 43 member B 1 20552439-20555010 Predicted intracellular proteins Evidence at protein level HPA050813 Approved Approved Cytosol Tissue enhanced Tissue enhanced adrenal gland: 10.3 epididymis: 3.5 Cell line enhanced AN3-CA: 2.9;fHDF/TERT166: 3.6;SCLC-21H: 4.8;SiHa: 8.3 +CSMD1 KIAA1890, PPP1R24 ENSG00000183117 CUB and Sushi multiple domains 1 8 2935353-4994972 Predicted membrane proteins Evidence at protein level HPA074707 Approved Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 6.2;testis: 4.7 fallopian tube: 1.1 Cell line enhanced K-562: 4.4;U-2 OS: 2.3;U-266/70: 1.7;U-266/84: 1.5;U-698: 1.3 +CALHM3 bA225H22.7, FAM26A ENSG00000183128 Calcium homeostasis modulator 3 10 103472804-103479240 Predicted membrane proteins, Transporters Evidence at transcript level HPA018205 Uncertain Approved Nucleoplasm Tissue enhanced Not detected testis: 0.4 Cell line enhanced CAPAN-2: 2.2;U-266/84: 10.0 +PTGDR2 CD294, CRTH2, DP2, GPR44 ENSG00000183134 Prostaglandin D2 receptor 2 11 60850940-60855971 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA014259 Uncertain Mixed Tissue enhanced small intestine: 7.1;stomach: 7.5 parathyroid gland: 5.0 Cell line enhanced HEL: 8.5;Hep G2: 3.2;HMC-1: 5.1;K-562: 3.6;NB-4: 8.7 +CEP57L1 bA487F23.2, C6orf182, MGC21731 ENSG00000183137 Centrosomal protein 57 like 1 6 109095110-109163932 Predicted intracellular proteins Evidence at protein level HPA040378 Approved Approved Plasma membrane
Cytosol Expressed in all Expressed in all testis: 47.6 Expressed in all +RIPPLY3 DSCR6 ENSG00000183145 Ripply transcriptional repressor 3 21 37006150-37019659 Predicted intracellular proteins Evidence at transcript level HPA055541 Uncertain Mixed Not detected prostate: 0.2 Cell line enhanced SCLC-21H: 3.2;T-47d: 1.5 +PRORY CYorf17 ENSG00000183146 Proline rich, Y-linked Y 21382954-21386360 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced small intestine: 1.8 colon,rectum: 0.6 Cell line enhanced U-266/84: 2.4 +ANKRD20A2 ENSG00000183148 Ankyrin repeat domain 20 family member A2 9 40223285-40266392 Predicted intracellular proteins Evidence at transcript level HPA043239, HPA047112, HPA047167, HPA047766, HPA051753 Uncertain Not detected Tissue enriched 6 testis: 4.9 spleen: 0.7 Cell line enhanced Karpas-707: 9.3;U-266/84: 2.9 +GPR19 ENSG00000183150 G protein-coupled receptor 19 12 12660891-12696207 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013955 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 8.4;testis: 7.8 appendix: 2.7 Cell line enhanced HDLM-2: 37.0;NTERA-2: 39.8 +GJD3 Cx30.2, CX31.9, GJA11, GJC1 ENSG00000183153 Gap junction protein delta 3 17 40362931-40363815 Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced spleen: 7.0 stomach: 2.7 Cell line enhanced BEWO: 14.7 +RABIF mss4, RASGRF3 ENSG00000183155 RAB interacting factor 1 202878957-202889135 Predicted intracellular proteins Evidence at protein level HPA027715, HPA054936 Approved Approved Microtubules
Cytokinetic bridge Renal cancer:2.61e-5 (unfavourable), Ovarian cancer:5.64e-5 (favourable), Liver cancer:1.55e-4 (unfavourable) Expressed in all Mixed testis: 26.1 Expressed in all +TMEM119 ENSG00000183160 Transmembrane protein 119 12 108589846-108598320 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA051870, HPA052650 Enhanced Renal cancer:2.06e-6 (unfavourable), Ovarian cancer:8.37e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 93.0 gallbladder: 55.2 Cell line enhanced ASC diff: 378.8;ASC TERT1: 106.4;BJ hTERT+: 134.8;HSkMC: 171.1 +FANCF FAF ENSG00000183161 Fanconi anemia complementation group F 11 22622519-22626787 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Liver cancer:2.27e-4 (unfavourable) Expressed in all Mixed fallopian tube: 10.8 Cell line enhanced SCLC-21H: 29.4 +CALN1 ENSG00000183166 Calneuron 1 7 71779491-72447151 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036278, HPA036708 Approved Uncertain Vesicles
Plasma membrane Mixed Group enriched 5 adrenal gland: 14.7;cerebral cortex: 46.4 testis: 6.0 Cell line enhanced Karpas-707: 33.8;NTERA-2: 6.0;REH: 6.4;SCLC-21H: 7.8;U-2 OS: 7.6 +SMDT1 C22orf32, DDDD, dJ186O1.1, EMRE ENSG00000183172 Single-pass membrane protein with aspartate rich tail 1 22 42079691-42084284 Predicted membrane proteins, Transporters Evidence at protein level HPA032117, HPA060340 Uncertain Supported Nucleus
Mitochondria Renal cancer:2.36e-9 (favourable), Endometrial cancer:5.32e-8 (favourable), Pancreatic cancer:5.87e-4 (favourable) Expressed in all Expressed in all thyroid gland: 7.8 Mixed +GABRR3 ENSG00000183185 Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) 3 97986673-98035304 FDA approved drug targets, Predicted membrane proteins No evidence Not detected Not detected testis: 0.2 Not detected +C2CD4C FAM148C, KIAA1957, NLF3 ENSG00000183186 C2 calcium dependent domain containing 4C 19 405438-409170 Predicted intracellular proteins Evidence at protein level HPA055915 Uncertain Approved Vesicles Tissue enhanced Group enriched 6 adipose tissue: 2.6;cerebral cortex: 10.6;gallbladder: 4.4 endometrium: 0.9 Cell line enhanced HDLM-2: 5.9;NTERA-2: 6.2;SCLC-21H: 13.0;U-2 OS: 6.8 +CHST6 MCDC1 ENSG00000183196 Carbohydrate sulfotransferase 6 16 75472052-75495384 Disease related genes, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced cervix, uterine: 16.3;duodenum: 10.6;small intestine: 10.9 cerebral cortex: 7.9 Cell line enhanced AN3-CA: 10.8;CAPAN-2: 11.4;NTERA-2: 6.2;U-2 OS: 8.0;WM-115: 6.7 +POTEC A26B2, CT104.6, DKFZp686J0529, POTE-18, POTE18 ENSG00000183206 POTE ankyrin domain family member C 18 14507339-14543585 Predicted intracellular proteins Evidence at transcript level HPA042822 Uncertain Not detected Tissue enriched 14 testis: 1.4 prostate: 0.1 Not detected +RUVBL2 ECP51, INO80J, Reptin52, RVB2, TIH2, TIP48, TIP49b ENSG00000183207 RuvB like AAA ATPase 2 19 48993448-49015995 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012432, HPA042880, HPA067966 Enhanced Supported Nucleoplasm
Centrosome
Cytosol Liver cancer:9.28e-4 (unfavourable) Expressed in all Expressed in all testis: 72.4 Expressed in all +GDPGP1 C15orf58 ENSG00000183208 GDP-D-glucose phosphorylase 1 15 90233808-90245811 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048189, HPA059841 Approved Approved Cytosol Breast cancer:6.32e-4 (favourable) Expressed in all Mixed parathyroid gland: 9.6 Mixed +CTNNA3 MGC26194, VR22 ENSG00000183230 Catenin alpha 3 10 65912518-67696169 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA061818 Enhanced Tissue enhanced Tissue enhanced cerebral cortex: 8.5;heart muscle: 12.4 liver: 4.4 Cell line enhanced Daudi: 1.7;NTERA-2: 1.7;RPMI-8226: 1.6;SCLC-21H: 1.8;U-266/70: 5.0 +RIMBP3C ENSG00000183246 RIMS binding protein 3C 22 21545357-21551461 Predicted intracellular proteins Evidence at protein level HPA001183 Supported Uncertain Vesicles
Plasma membrane Not detected Tissue enriched 32 testis: 15.7 spleen: 0.4 Not detected +PRR36 ENSG00000183248 Proline rich 36 19 7868719-7874379 Predicted intracellular proteins Evidence at protein level HPA062741 Uncertain Approved Nucleus
Golgi apparatus Testis cancer:7.74e-4 (favourable) Mixed Tissue enriched 9 cerebral cortex: 18.0 prostate: 1.9 Cell line enhanced REH: 26.2;SCLC-21H: 9.4;SH-SY5Y: 19.0 +OR51B4 ENSG00000183251 Olfactory receptor family 51 subfamily B member 4 11 5301014-5301996 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.2 Group enriched 8 K-562: 3.2;U-2197: 4.1 +PTTG1IP C21orf1, C21orf3, PBF ENSG00000183255 Pituitary tumor-transforming 1 interacting protein 21 44849585-44873903 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB034146, HPA061827 Uncertain Supported Nucleoplasm Pancreatic cancer:2.28e-4 (unfavourable), Stomach cancer:5.40e-4 (unfavourable), Cervical cancer:8.61e-4 (unfavourable) Expressed in all Expressed in all placenta: 243.5 Expressed in all +DDX41 ABS, MGC8828 ENSG00000183258 DEAD-box helicase 41 5 177511577-177517469 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017911, HPA048803 Enhanced Supported Nucleus Renal cancer:2.21e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 52.6 Expressed in all +ABHD16B C20orf135, dJ591C20.1 ENSG00000183260 Abhydrolase domain containing 16B 20 63861498-63862988 Plasma proteins, Predicted intracellular proteins Evidence at transcript level HPA059272 Uncertain Approved Nucleoplasm Not detected Mixed testis: 5.7 Cell line enhanced PC-3: 17.5 +OR52E8 ENSG00000183269 Olfactory receptor family 52 subfamily E member 8 11 5856674-5857734 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +CCDC60 MGC39827 ENSG00000183273 Coiled-coil domain containing 60 12 119334712-119541047 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced fallopian tube: 28.0;testis: 19.7 cervix, uterine: 8.2 Not detected +PLGLB1 PLGL, PRP-B ENSG00000183281 Plasminogen-like B1 2 87002559-87021852 Predicted secreted proteins Evidence at transcript level HPA053770 Approved Vesicles Tissue enriched Tissue enriched 8 liver: 120.5 skin: 15.4 Mixed +DAZAP2 KIAA0058 ENSG00000183283 DAZ associated protein 2 12 51238292-51271362 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045940 Supported Nuclear speckles Renal cancer:3.94e-9 (favourable) Expressed in all Expressed in all bone marrow: 336.1 Expressed in all +CCBE1 FLJ30681, KIAA1983 ENSG00000183287 Collagen and calcium binding EGF domains 1 18 59430940-59697380 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041361, HPA041374 Uncertain Enhanced Plasma membrane
Cytosol Mixed Tissue enhanced ovary: 40.6 cervix, uterine: 16.0 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 91.8;HBF TERT88: 109.2;hTERT-HME1: 117.8;LHCN-M2: 146.3 +SELENOF SEP15 ENSG00000183291 Selenoprotein F 1 86862445-86914424 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054937 Approved Nucleoli
Cytosol Liver cancer:1.98e-5 (unfavourable), Colorectal cancer:6.53e-4 (favourable), Head and neck cancer:8.17e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 361.7 Expressed in all +TISP43 ENSG00000183292 Uncharacterized LOC150527 2 130570829-130584161 Predicted intracellular proteins Evidence at transcript level HPA044732 Uncertain Not detected Tissue enriched 11 testis: 11.5 skin: 1.0 Not detected +OR5P2 JCG3 ENSG00000183303 Olfactory receptor family 5 subfamily P member 2 11 7795905-7796973 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected skin: 0.1 Not detected +FAM9A TEX39A ENSG00000183304 Family with sequence similarity 9 member A X 8790795-8801383 Predicted intracellular proteins Evidence at protein level HPA056076 Uncertain Not detected Tissue enriched 25 testis: 7.2 adrenal gland,cerebral cortex: 0.2 Cell line enriched 16 U-266/84: 6.2 +MAGEA2B MAGE2, MAGEA2, MAGEA2b, MGC16973 ENSG00000183305 MAGE family member A2B X 152714586-152718607 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 9 testis: 1.9 placenta: 0.2 Cell line enhanced BEWO: 36.8;HMC-1: 34.9;K-562: 31.7;SH-SY5Y: 56.8;U-266/70: 21.5;U-266/84: 32.0 +CECR6 ENSG00000183307 Cat eye syndrome chromosome region, candidate 6 22 17116299-17121367 Predicted membrane proteins Evidence at protein level HPA068790 Approved Approved Nucleoplasm
Vesicles
Plasma membrane Tissue enhanced Group enriched 7 cerebral cortex: 15.0;prostate: 10.8 testis: 1.9 Cell line enhanced AF22: 5.9;SCLC-21H: 16.7;THP-1: 8.0;U-937: 7.7 +ZNF623 KIAA0628 ENSG00000183309 Zinc finger protein 623 8 143636013-143656418 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA044372 Uncertain Approved Nucleus Endometrial cancer:2.94e-4 (unfavourable) Expressed in all Mixed endometrium: 6.2 Cell line enhanced SiHa: 24.6 +OR2T34 ENSG00000183310 Olfactory receptor family 2 subfamily T member 34 1 248573801-248574757 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR52L1 ENSG00000183313 Olfactory receptor family 52 subfamily L member 1 11 5985892-5986985 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.1 Not detected +EPHA10 FLJ16103, FLJ33655 ENSG00000183317 EPH receptor A10 1 37713880-37765133 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA027497 Uncertain Mixed Tissue enhanced testis: 20.4 colon: 7.9 Cell line enhanced BEWO: 4.7;HDLM-2: 18.1;SCLC-21H: 10.2 +SPDYE4 ENSG00000183318 Speedy/RINGO cell cycle regulator family member E4 17 8753106-8758559 Predicted intracellular proteins Evidence at protein level HPA025704, HPA051750 Enhanced Not detected Tissue enriched 20 testis: 10.5 bone marrow: 0.5 Cell line enhanced A549: 1.4;HeLa: 1.1 +CCDC125 KENAE ENSG00000183323 Coiled-coil domain containing 125 5 69280175-69332809 Predicted intracellular proteins Evidence at protein level HPA041878 Approved Uncertain Nucleoplasm
Nuclear membrane
Intermediate filaments Urothelial cancer:2.51e-4 (favourable), Endometrial cancer:4.40e-4 (favourable), Breast cancer:8.06e-4 (unfavourable) Expressed in all Mixed prostate: 11.5 Cell line enhanced T-47d: 25.4 +REC114 C15orf60, CT147, FLJ27520, FLJ36860, FLJ44083, LOC283677 ENSG00000183324 REC114 meiotic recombination protein 15 73443158-73560014 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 96 testis: 63.6 heart muscle: 0.6 Not detected +BOLA2 BOLA2A, My016 ENSG00000183336 BolA family member 2 16 29443056-29454964 Predicted intracellular proteins Evidence at protein level HPA045380, HPA046696 Supported Uncertain Nucleus Not detected Mixed duodenum: 12.0 Mixed +BCOR FLJ20285, KIAA1575 ENSG00000183337 BCL6 corepressor X 40049815-40177329 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056308, HPA073591 Enhanced Nucleus Liver cancer:1.30e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.0 Expressed in all +JRKL HHMJG ENSG00000183340 JRK-like 11 96389989-96507574 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046184, HPA060341 Uncertain Approved Nucleus
Cytokinetic bridge Expressed in all Expressed in all parathyroid gland: 19.2 Expressed in all +C10orf107 bA63A2.1, Em:AC022398.2, MGC44593 ENSG00000183346 Chromosome 10 open reading frame 107 10 61662961-61766766 Predicted intracellular proteins Evidence at protein level HPA041398 Enhanced Uncertain Nucleoplasm
Centrosome
Cytosol Endometrial cancer:1.79e-4 (favourable), Glioma:3.99e-4 (unfavourable) Mixed Tissue enhanced fallopian tube: 44.2;testis: 30.5 parathyroid gland: 12.6 Group enriched 6 MOLT-4: 21.5;SH-SY5Y: 6.0 +GBP6 DKFZp686G0786 ENSG00000183347 Guanylate binding protein family member 6 1 89364058-89386461 Predicted intracellular proteins Evidence at protein level HPA027744 Enhanced Group enriched Tissue enriched 7 esophagus: 448.5 tonsil: 65.9 Group enriched 10 A-431: 6.0;HaCaT: 13.1 +KIAA2026 FLJ20375 ENSG00000183354 KIAA2026 9 5881596-6007901 Predicted intracellular proteins Evidence at protein level HPA002109 Uncertain Approved Nucleus
Vesicles
Cytosol Renal cancer:8.34e-4 (favourable) Expressed in all Expressed in all testis: 23.0 Expressed in all +OVCH2 OVTN ENSG00000183378 Ovochymase 2 (gene/pseudogene) 11 7689438-7706421 Predicted secreted proteins Evidence at protein level Mixed Tissue enriched 22 epididymis: 205.6 skin: 9.5 Cell line enriched 7 REH: 20.7 +SYNDIG1L capucin, IFITMD4, TMEM90A ENSG00000183379 Synapse differentiation inducing 1 like 14 74405893-74426102 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA042594, HPA048487 Uncertain Mixed Tissue enriched 10 epididymis: 13.4 lung: 1.3 Not detected +FHL3 SLIM2 ENSG00000183386 Four and a half LIM domains 3 1 37996770-38005606 Predicted intracellular proteins Evidence at protein level HPA045723 Approved Nucleus Renal cancer:4.20e-11 (unfavourable), Liver cancer:8.59e-5 (unfavourable), Breast cancer:5.62e-4 (favourable) Expressed in all Tissue enriched 13 skeletal muscle: 569.1 smooth muscle: 43.5 Mixed +OR56A4 ENSG00000183389 Olfactory receptor family 56 subfamily A member 4 11 6001986-6003194 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +PMCH MCH ENSG00000183395 Pro-melanin concentrating hormone 12 102196459-102197845 Predicted secreted proteins Evidence at protein level HPA046055, HPA061884 Enhanced Tissue enhanced Tissue enhanced lymph node: 1.1 appendix: 0.7 Cell line enriched 9 HDLM-2: 40.8 +TMEM89 ENSG00000183396 Transmembrane protein 89 3 48620759-48621855 Predicted membrane proteins Evidence at protein level HPA053577 Uncertain Not detected Tissue enriched 10 testis: 9.4 bone marrow: 0.9 Not detected +C19orf71 LOC100128569 ENSG00000183397 Chromosome 19 open reading frame 71 19 3539154-3544030 Predicted intracellular proteins Evidence at protein level HPA048654 Uncertain Approved Endoplasmic reticulum
Plasma membrane
Cytosol Renal cancer:2.02e-5 (favourable), Pancreatic cancer:2.03e-5 (favourable), Head and neck cancer:2.35e-4 (favourable) Tissue enriched Mixed testis: 29.5 Cell line enhanced HeLa: 52.4;WM-115: 167.8 +CCDC159 ENSG00000183401 Coiled-coil domain containing 159 19 11344684-11354944 Predicted intracellular proteins Evidence at protein level HPA047126, HPA054655 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Endometrial cancer:1.87e-7 (favourable), Pancreatic cancer:1.42e-4 (favourable), Urothelial cancer:8.62e-4 (favourable), Ovarian cancer:9.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 65.5 Mixed +RIPK4 ANKK2, ANKRD3, DIK, PKK, RIP4 ENSG00000183421 Receptor interacting serine/threonine kinase 4 21 41739369-41767106 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA030942 Enhanced Ovarian cancer:6.22e-5 (unfavourable), Pancreatic cancer:3.48e-4 (unfavourable), Renal cancer:6.52e-4 (favourable) Mixed Tissue enhanced esophagus: 31.5 small intestine: 15.0 Cell line enhanced CAPAN-2: 27.8;HaCaT: 41.4 +LRIT3 CSNB1F, FIGLER4, FLJ44691 ENSG00000183423 Leucine rich repeat, Ig-like and transmembrane domains 3 4 109848202-109872315 Disease related genes, Predicted membrane proteins Evidence at protein level HPA013454 Supported Approved Nucleoplasm
Mitochondria
Cytosol Not detected Not detected kidney: 0.9 Not detected +NPIPA1 morpheus, NPIP ENSG00000183426 Nuclear pore complex interacting protein family member A1 16 14922802-14952060 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA053611 Supported Approved Nucleoplasm Mixed Mixed ovary: 68.6 Mixed +SF3A3 PRP9, PRPF9, SAP61, SF3a60 ENSG00000183431 Splicing factor 3a subunit 3 1 37956975-37990921 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA032054, HPA032055 Enhanced Enhanced Nucleoplasm Liver cancer:2.11e-8 (unfavourable) Expressed in all Expressed in all endometrium: 35.2 Expressed in all +TFDP3 CT30, E2F-like, HCA661 ENSG00000183434 Transcription factor Dp family member 3 X 133216669-133218348 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 81 testis: 8.0 all non-specific tissues: 0.0 Not detected +TRIM61 RNF35 ENSG00000183439 Tripartite motif containing 61 4 164954446-164977668 Predicted intracellular proteins Evidence at transcript level HPA049109 Uncertain Approved Nucleoli fibrillar center
Endoplasmic reticulum Tissue enhanced Tissue enhanced testis: 10.5 thyroid gland: 4.6 Cell line enhanced HHSteC: 6.6;U-266/70: 8.1;U-266/84: 4.0 +GRIN2A GluN2A, NMDAR2A ENSG00000183454 Glutamate ionotropic receptor NMDA type subunit 2A 16 9753404-10182754 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level CAB022725 Enhanced Mixed Tissue enhanced cerebral cortex: 25.8 testis: 6.1 Cell line enhanced fHDF/TERT166: 3.3;U-138 MG: 4.4 +URAD PRHOXNB ENSG00000183463 Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase 13 27977714-27988654 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA038972 Uncertain Tissue enriched Group enriched 6 colon: 12.6;duodenum: 8.3;small intestine: 17.9 appendix: 2.3 Group enriched 12 BEWO: 2.6;CACO-2: 2.1 +GTF2H2C ENSG00000183474 GTF2H2 family member C 5 69560208-69594723 Predicted intracellular proteins Evidence at protein level HPA047001 Approved Nuclear speckles Mixed Mixed thyroid gland: 8.3 Mixed +ASB7 ENSG00000183475 Ankyrin repeat and SOCS box containing 7 15 100602534-100651705 Predicted intracellular proteins Evidence at protein level HPA003300 Enhanced Approved Nucleus
Golgi apparatus
Vesicles Expressed in all Mixed testis: 12.5 Expressed in all +SH2D7 LOC646892 ENSG00000183476 SH2 domain containing 7 15 78077808-78104909 Predicted intracellular proteins Evidence at transcript level HPA051320 Approved Mixed Group enriched 7 colon: 1.6;duodenum: 2.1;small intestine: 1.9;testis: 5.7 cerebral cortex: 0.4 Cell line enhanced SH-SY5Y: 1.4 +TREX2 ENSG00000183479 Three prime repair exonuclease 2 X 153444720-153470587 Enzymes, Predicted intracellular proteins Evidence at protein level HPA054060 Uncertain Mixed Tissue enriched 8 skin: 28.8 seminal vesicle: 3.4 Cell line enhanced U-937: 5.4 +GPR132 G2A ENSG00000183484 G protein-coupled receptor 132 14 105049389-105065445 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029694, HPA029695 Supported Renal cancer:1.71e-5 (unfavourable), Cervical cancer:3.21e-4 (favourable), Head and neck cancer:6.44e-4 (favourable) Mixed Mixed appendix: 9.4 Group enriched 6 HDLM-2: 24.9;Karpas-707: 19.2;THP-1: 5.6 +MX2 MXB ENSG00000183486 MX dynamin like GTPase 2 21 41361943-41409390 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA030235 Uncertain Endometrial cancer:3.71e-5 (unfavourable) Expressed in all Mixed spleen: 45.5 Cell line enhanced BJ hTERT+ SV40 Large T+: 156.9;BJ hTERT+ SV40 Large T+ RasG12V: 158.8;MOLT-4: 89.4;U-266/84: 131.4;U-937: 146.7 +EP400 CAGH32, DKFZP434I225, KIAA1498, KIAA1818, P400, TNRC12 ENSG00000183495 E1A binding protein p400 12 131949920-132081102 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016704, HPA049013 Supported Supported Nucleus Liver cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all testis: 20.8 Expressed in all +MEX3B DKFZp434J0617, RKHD3, RNF195 ENSG00000183496 Mex-3 RNA binding family member B 15 82041778-82046141 Predicted intracellular proteins Evidence at protein level HPA041093 Enhanced Approved Nucleoplasm
Cytosol Mixed Tissue enhanced testis: 41.6 endometrium: 10.1 Cell line enhanced AN3-CA: 58.8;HEL: 43.1 +FAM46C FLJ20202 ENSG00000183508 Family with sequence similarity 46 member C 1 117605934-117628372 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA054049 Uncertain Approved Nucleoplasm Renal cancer:2.77e-5 (favourable), Endometrial cancer:3.75e-5 (favourable) Expressed in all Mixed testis: 58.7 Cell line enhanced Karpas-707: 208.6;RPMI-8226: 124.6;U-266/70: 61.2 +COA5 C2orf64, FLJ27524, MGC52110, Pet191 ENSG00000183513 Cytochrome c oxidase assembly factor 5 2 98599310-98608515 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA057768 Uncertain Supported Mitochondria Urothelial cancer:1.00e-5 (favourable), Lung cancer:2.65e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 42.3 Expressed in all +UTP11 CGI-94, UTP11L ENSG00000183520 UTP11, small subunit processome component homolog (S. cerevisiae) 1 38009258-38024824 Predicted intracellular proteins Evidence at protein level HPA045830 Approved Approved Nucleus Renal cancer:1.42e-8 (unfavourable), Liver cancer:7.44e-8 (unfavourable) Expressed in all Expressed in all skeletal muscle: 37.3 Expressed in all +PSMG1 c21-LRP, DSCR2, LRPC21, PAC1 ENSG00000183527 Proteasome assembly chaperone 1 21 39174769-39183851 Predicted intracellular proteins Evidence at protein level HPA057193, HPA070225 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:3.58e-5 (unfavourable) Expressed in all Expressed in all testis: 68.5 Expressed in all +PRR14L C22orf30, MGC50372 ENSG00000183530 Proline rich 14 like 22 31676256-31750140 Predicted intracellular proteins Evidence at protein level HPA062645 Uncertain Approved Nucleoplasm Renal cancer:3.00e-4 (favourable) Expressed in all Mixed parathyroid gland: 15.2 Expressed in all +KLRC4 NKG2-F ENSG00000183542 Killer cell lectin like receptor C4 12 10407382-10409757 Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced spleen: 13.1 lymph node: 5.6 Cell line enhanced HeLa: 3.1;U-698: 1.1 +ACSM5 FLJ20581 ENSG00000183549 Acyl-CoA synthetase medium-chain family member 5 16 20409534-20441336 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041435 Uncertain Group enriched Tissue enriched 5 liver: 142.6 adipose tissue: 26.9 Group enriched 5 ASC diff: 3.6;ASC TERT1: 8.0;HSkMC: 10.0;U-87 MG: 8.4 +C10orf120 bA318C4.1 ENSG00000183559 Chromosome 10 open reading frame 120 10 122697709-122699822 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 375 testis: 49.4 epididymis: 0.1 Not detected +IZUMO1R Folbp3, FOLR4, JUNO ENSG00000183560 IZUMO1 receptor, JUNO 11 94305592-94307721 Predicted secreted proteins, Transporters Evidence at protein level Not detected Not detected adrenal gland: 0.8 Not detected +SERHL2 ENSG00000183569 Serine hydrolase-like 2 22 42553617-42574382 Plasma proteins, Predicted intracellular proteins Evidence at transcript level Group enriched Tissue enriched 12 breast: 558.7 epididymis: 45.4 Cell line enriched 9 SK-BR-3: 207.3 +PCBP3 FLJ44028, PCBP3-OT1, PCBP3OT ENSG00000183570 Poly(rC) binding protein 3 21 45643694-45942454 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030247 Approved Mixed Tissue enhanced testis: 21.6 cerebral cortex: 12.7 Cell line enhanced HDLM-2: 53.3;HSkMC: 30.0;SH-SY5Y: 50.2;U-87 MG: 24.6;U-937: 24.7 +PGPEP1L ENSG00000183571 Pyroglutamyl-peptidase I-like 15 98968230-99007795 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA041781 Uncertain Not detected Group enriched 6 heart muscle: 2.4;skeletal muscle: 10.5;testis: 3.8 breast,esophagus: 0.9 Cell line enhanced U-2 OS: 1.1 +SETD3 C14orf154, FLJ23027 ENSG00000183576 SET domain containing 3 14 99397746-99480889 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003591, HPA003639 Approved Approved Mitochondria Renal cancer:1.89e-15 (favourable), Head and neck cancer:6.46e-4 (unfavourable) Expressed in all Expressed in all testis: 154.4 Expressed in all +TNFAIP8L3 FLJ41287 ENSG00000183578 TNF alpha induced protein 8 like 3 15 51056598-51105276 Predicted intracellular proteins Evidence at protein level HPA048372, HPA077484 Uncertain Approved Nucleoplasm
Cytosol Urothelial cancer:3.51e-4 (unfavourable) Expressed in all Tissue enhanced endometrium: 137.0;smooth muscle: 122.3 fallopian tube: 38.9 Cell line enhanced ASC TERT1: 61.0;HUVEC TERT2: 64.8;LHCN-M2: 60.7;TIME: 85.7 +ZNRF3 BK747E2.3, FLJ22057, KIAA1133, RNF203 ENSG00000183579 Zinc and ring finger 3 22 28883592-29057487 Enzymes, Predicted membrane proteins Evidence at protein level HPA036702, HPA036703 Uncertain Uncertain Golgi apparatus Not detected Mixed epididymis: 16.4 Cell line enhanced Hep G2: 31.1 +FBXL7 FBL6, FBL7, KIAA0840 ENSG00000183580 F-box and leucine rich repeat protein 7 5 15500196-15939795 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055464 Uncertain Liver cancer:1.29e-4 (unfavourable), Thyroid cancer:6.69e-4 (unfavourable) Expressed in all Mixed endometrium,smooth muscle: 36.6 Mixed +TANGO2 C22orf25, DKFZp761P1121 ENSG00000183597 Transport and golgi organization 2 homolog 22 20017014-20065926 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003080 Approved Approved Pancreatic cancer:3.01e-4 (favourable) Expressed in all Expressed in all heart muscle: 47.5 Expressed in all +HIST2H3D ENSG00000183598 Histone cluster 2 H3 family member d 1 149813271-149813681 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Mixed Tissue enhanced bone marrow: 2.5 gallbladder: 1.8 Cell line enhanced U-266/70: 16.7 +SFXN4 ENSG00000183605 Sideroflexin 4 10 119140767-119165667 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018028, HPA020872 Approved Supported Vesicles Expressed in all Expressed in all thyroid gland: 47.3 Expressed in all +GKN2 blottin, BRICD1B, GDDR, PRO813, TFIZ1, VLTI465 ENSG00000183607 Gastrokine 2 2 68945232-68952970 Predicted secreted proteins Evidence at protein level HPA057765 Enhanced Tissue enriched Tissue enriched 37 stomach: 3843.6 lung: 103.7 Cell line enhanced A549: 1.6;HMC-1: 1.5;NTERA-2: 2.1;PC-3: 3.6;U-2 OS: 1.5;U-266/70: 1.3 +FAM167B C1orf90, MGC10820 ENSG00000183615 Family with sequence similarity 167 member B 1 32247233-32248856 Predicted intracellular proteins Evidence at protein level HPA029398, HPA062074 Approved Approved Actin filaments Colorectal cancer:1.11e-4 (unfavourable) Expressed in all Mixed thyroid gland: 9.4 Cell line enhanced EFO-21: 11.4;SK-MEL-30: 23.7;U-2197: 28.2 +MRPL54 ENSG00000183617 Mitochondrial ribosomal protein L54 19 3762664-3768575 Predicted intracellular proteins Evidence at protein level HPA042117, HPA046767 Uncertain Approved Mitochondria Expressed in all Expressed in all thyroid gland: 90.1 Expressed in all +ZNF438 bA330O11.1 ENSG00000183621 Zinc finger protein 438 10 30820207-31031937 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA039843 Uncertain Supported Nucleoplasm
Cytosol Expressed in all Mixed thyroid gland: 16.2 Cell line enhanced U-937: 19.8 +HMCES C3orf37, DC12, SRAPD1 ENSG00000183624 5-hydroxymethylcytosine binding, ES cell specific 3 129278828-129306186 Predicted intracellular proteins Evidence at protein level HPA044968 Approved Approved Nucleus Liver cancer:4.41e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 205.0 Expressed in all +CCR3 CC-CKR-3, CD193, CKR3, CMKBR3 ENSG00000183625 C-C motif chemokine receptor 3 3 46163604-46266706 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB003795 Uncertain Not detected Mixed small intestine: 2.9 Cell line enriched 9 RPMI-8226: 20.3 +DGCR6 ENSG00000183628 DiGeorge syndrome critical region gene 6 22 18906028-18914238 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 11.7 thyroid gland: 4.9 Mixed +GOLGA8G DKFZp434K052 ENSG00000183629 Golgin A8 family member G 15 28519611-28533014 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 35 testis: 3.5 all non-specific tissues: 0.0 Not detected +PRR32 CXorf64 ENSG00000183631 Proline rich 32 X 126819764-126821786 Predicted intracellular proteins No evidence HPA048386 Uncertain Tissue enriched Not detected fallopian tube: 0.9 Not detected +TP53TG3 P53TG3, TP53TG3A ENSG00000183632 TP53 target 3 16 32673528-32676732 Predicted intracellular proteins Evidence at transcript level Not detected Not detected cerebral cortex: 0.3 Not detected +RP1L1 DCDC4B ENSG00000183638 RP1 like 1 8 10606349-10712187 Predicted intracellular proteins Evidence at protein level HPA024686, HPA024744 Enhanced Not detected Not detected skin: 0.2 Not detected +KRTAP8-1 KAP8.1 ENSG00000183640 Keratin associated protein 8-1 21 30812697-30813252 Predicted intracellular proteins Evidence at protein level Tissue enriched Not detected testis: 0.3 Not detected +C11orf88 FLJ46266 ENSG00000183644 Chromosome 11 open reading frame 88 11 111514785-111537031 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Group enriched 5 fallopian tube: 141.7;testis: 39.5 lung: 17.8 Cell line enhanced CACO-2: 1.3;Karpas-707: 1.2 +ZNF530 KIAA1508 ENSG00000183647 Zinc finger protein 530 19 57599885-57612722 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045868 Uncertain Approved Vesicles Mixed Mixed spleen: 3.1 Cell line enhanced HEK 293: 68.7;U-266/84: 40.3 +NDUFB1 CI-MNLL, MNLL ENSG00000183648 NADH:ubiquinone oxidoreductase subunit B1 14 92116122-92121917 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA063737 Supported Nuclear speckles
Mitochondria Renal cancer:1.31e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 278.8 Expressed in all +MARCH11 MARCH-XI ENSG00000183654 Membrane associated ring-CH-type finger 11 5 16067139-16180762 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 20 testis: 90.3 cerebral cortex: 4.5 Cell line enriched 13 SH-SY5Y: 89.2 +KLHL25 ENC-2, ENC2, FLJ12587 ENSG00000183655 Kelch like family member 25 15 85759323-85795030 Predicted intracellular proteins Evidence at protein level HPA023450 Approved Approved Nucleoplasm
Cytosol Expressed in all Tissue enhanced cerebral cortex: 15.8 testis: 9.9 Mixed +FAM19A1 TAFA-1, TAFA1 ENSG00000183662 Family with sequence similarity 19 member A1, C-C motif chemokine like 3 68004216-68545625 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA013407 Approved Tissue enhanced Tissue enriched 6 cerebral cortex: 30.8 seminal vesicle: 5.3 Cell line enriched 9 REH: 1.5 +TRMT12 FLJ20772, Trm12, TYW2 ENSG00000183665 TRNA methyltransferase 12 homolog 8 124450820-124462150 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023939 Approved Approved Nucleoplasm
Mitochondria Head and neck cancer:2.99e-5 (unfavourable), Liver cancer:5.10e-4 (unfavourable), Thyroid cancer:9.25e-4 (unfavourable) Expressed in all Mixed thyroid gland: 14.7 Cell line enhanced MCF7: 55.6 +PSG9 PSG11, PSGII ENSG00000183668 Pregnancy specific beta-1-glycoprotein 9 19 43211791-43269530 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA046327 Approved Not detected Tissue enriched 118 placenta: 147.0 smooth muscle: 1.2 Cell line enhanced BJ: 4.4;BJ hTERT+ SV40 Large T+: 4.2;HBF TERT88: 9.0;T-47d: 4.0;U-2197: 9.0 +GPR1 ENSG00000183671 G protein-coupled receptor 1 2 206175316-206218047 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010525 Uncertain Supported Nucleoplasm
Vesicles
Plasma membrane Mixed Tissue enhanced placenta: 5.6 esophagus: 2.7 Cell line enhanced HHSteC: 112.4;hTCEpi: 44.7 +BMP8A ENSG00000183682 Bone morphogenetic protein 8a 1 39491646-39525935 Predicted secreted proteins Evidence at transcript level Mixed Tissue enriched 19 thyroid gland: 82.0 testis: 4.4 Cell line enhanced U-2197: 12.8;U-266/70: 5.4;U-266/84: 4.6 +ALYREF ALY, ALY/REF, BEF, REF, THOC4 ENSG00000183684 Aly/REF export factor 17 81887844-81891586 Predicted intracellular proteins Evidence at protein level CAB016281, HPA019799, HPA061282 Supported Enhanced Nuclear speckles Liver cancer:1.18e-4 (unfavourable) Expressed in all Expressed in all testis: 88.5 Expressed in all +RFLNB Cfm1, FAM101B, MGC45871, RefilinB ENSG00000183688 Refilin B 17 439978-445939 Predicted intracellular proteins Evidence at protein level HPA030879, HPA060388 Enhanced Approved Plasma membrane
Actin filaments
Cytosol Renal cancer:1.54e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 49.3 placenta: 15.2 Cell line enhanced fHDF/TERT166: 74.0;HMC-1: 195.7 +EFHC2 FLJ22843, MRX74 ENSG00000183690 EF-hand domain containing 2 X 44147882-44343672 Predicted intracellular proteins Evidence at protein level HPA034492 Uncertain Supported Mixed Tissue enhanced fallopian tube: 25.8;testis: 15.4 endometrium: 6.8 Group enriched 5 CAPAN-2: 3.8;HEL: 4.2;HMC-1: 13.1 +NOG SYM1, SYNS1 ENSG00000183691 Noggin 17 56593699-56595590 Disease related genes, Predicted secreted proteins Evidence at protein level HPA061318 Approved Pancreatic cancer:6.86e-5 (unfavourable), Endometrial cancer:6.66e-4 (favourable) Mixed Group enriched 5 cerebral cortex: 7.3;placenta: 15.8 lymph node: 2.2 Cell line enhanced EFO-21: 117.5;LHCN-M2: 32.2;PC-3: 35.7;U-2 OS: 40.3 +MRGPRX2 MRGX2 ENSG00000183695 MAS related GPR family member X2 11 19054455-19060681 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA055220 Approved Not detected Tissue enhanced breast: 1.2;skin: 1.2 cervix, uterine: 0.6 Not detected +UPP1 UDRPASE, UP, UPASE, UPP ENSG00000183696 Uridine phosphorylase 1 7 48088628-48108733 Enzymes, Predicted intracellular proteins Evidence at protein level HPA054040, HPA055394 Enhanced Enhanced Nucleoplasm Cervical cancer:1.02e-4 (unfavourable), Lung cancer:1.97e-4 (unfavourable) Expressed in all Tissue enhanced esophagus: 35.1 appendix: 17.8 Cell line enhanced hTERT-HME1: 369.7;WM-115: 110.3 +OR4N4 ENSG00000183706 Olfactory receptor family 4 subfamily N member 4 15 22094431-22095556 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA057442 Uncertain Uncertain Centrosome Not detected Tissue enriched 103 testis: 10.4 cervix, uterine: 0.1 Not detected +IFNL2 IL-28A, IL28A ENSG00000183709 Interferon lambda 2 19 39268514-39270092 Predicted secreted proteins Evidence at transcript level CAB025489 Uncertain Not detected Not detected pancreas,testis: 0.1 Cell line enriched 27 HDLM-2: 11.7 +OPCML IGLON1, OBCAM, OPCM ENSG00000183715 Opioid binding protein/cell adhesion molecule like 11 132414977-133532519 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Group enriched Tissue enriched 8 cerebral cortex: 63.0 parathyroid gland: 7.5 Cell line enhanced BJ: 7.9;HDLM-2: 1.8 +TRIM52 RNF102 ENSG00000183718 Tripartite motif containing 52 5 181254417-181261139 Predicted intracellular proteins Evidence at protein level HPA054565, HPA056819 Uncertain Supported Nucleoli
Intermediate filaments Renal cancer:3.46e-4 (unfavourable), Urothelial cancer:4.07e-4 (favourable) Expressed in all Expressed in all spleen: 16.6 Expressed in all +LHFP MGC22429 ENSG00000183722 Lipoma HMGIC fusion partner 13 39342892-39603528 Cancer-related genes, Disease related genes, Predicted membrane proteins Evidence at protein level HPA058975 Approved Approved Nucleoli Renal cancer:1.20e-7 (unfavourable), Urothelial cancer:2.30e-4 (unfavourable) Expressed in all Mixed placenta: 196.1 Cell line enhanced ASC diff: 177.4;HSkMC: 137.4 +CMTM4 CKLFSF4 ENSG00000183723 CKLF like MARVEL transmembrane domain containing 4 16 66614750-66696707 Predicted membrane proteins Evidence at protein level HPA014704, HPA023890 Enhanced Approved Golgi apparatus
Vesicles
Plasma membrane Renal cancer:4.72e-9 (favourable) Expressed in all Tissue enhanced thyroid gland: 64.1 parathyroid gland: 47.8 Mixed +TMEM50A SMP1 ENSG00000183726 Transmembrane protein 50A 1 25337917-25362361 Predicted membrane proteins, Transporters Evidence at protein level HPA065192 Approved Plasma membrane
Actin filaments
Cytosol Endometrial cancer:8.64e-5 (favourable), Liver cancer:3.34e-4 (unfavourable) Expressed in all Expressed in all prostate: 71.2 Expressed in all +NPBWR1 GPR7 ENSG00000183729 Neuropeptides B and W receptor 1 8 52938431-52941117 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Not detected cerebral cortex: 0.7 Cell line enhanced SiHa: 1.2 +FIGLA bHLHc8 ENSG00000183733 Folliculogenesis specific bHLH transcription factor 2 70777310-70790643 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Tissue enriched 6 testis: 1.2 cervix, uterine: 0.2 Not detected +ASCL2 ASH2, bHLHa45, HASH2 ENSG00000183734 Achaete-scute family bHLH transcription factor 2 11 2268495-2270952 Predicted intracellular proteins, Transcription factors Evidence at protein level Pancreatic cancer:4.73e-4 (favourable), Cervical cancer:5.11e-4 (favourable) Group enriched Mixed placenta: 6.4 Group enriched 6 BEWO: 19.9;NB-4: 4.0;SCLC-21H: 19.8 +TBK1 NAK ENSG00000183735 TANK binding kinase 1 12 64451880-64502108 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA045797, HPA060211 Uncertain Supported Nucleoplasm Renal cancer:4.20e-6 (unfavourable), Liver cancer:3.30e-4 (unfavourable), Melanoma:3.48e-4 (unfavourable) Expressed in all Expressed in all testis: 49.3 Expressed in all +CBX6 ENSG00000183741 Chromobox 6 22 38861450-38872314 Predicted intracellular proteins Evidence at protein level HPA048653 Uncertain Approved Nucleus
Mitochondria Pancreatic cancer:2.46e-6 (favourable), Liver cancer:8.30e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 105.8 Expressed in all +MACC1 7A5, SH3BP4L ENSG00000183742 MACC1, MET transcriptional regulator 7 20134655-20217404 Predicted intracellular proteins Evidence at protein level HPA020081, HPA020103, HPA029476, CAB068194 Supported Approved Mitochondria Renal cancer:5.71e-9 (favourable), Endometrial cancer:1.56e-5 (unfavourable) Mixed Mixed small intestine: 13.0 Cell line enhanced A-431: 85.3;HaCaT: 59.0 +ACSM2A A-923A4.1, ACSM2, MGC150530 ENSG00000183747 Acyl-CoA synthetase medium-chain family member 2A 16 20451461-20487667 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA057699 Supported Liver cancer:1.41e-5 (favourable) Group enriched Group enriched 580 kidney: 285.2;liver: 185.7 cerebral cortex: 0.4 Cell line enhanced Hep G2: 1.3 +TBL3 SAZD, UTP13 ENSG00000183751 Transducin beta like 3 16 1972037-1982933 Predicted intracellular proteins Evidence at protein level HPA042562, HPA055695 Enhanced Supported Enhanced Nucleoli Renal cancer:7.33e-4 (favourable) Expressed in all Mixed testis: 5.6 Expressed in all +BPY2 BPY2A, VCY2, VCY2A ENSG00000183753 Basic charge, Y-linked, 2 Y 22973819-23005465 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 11 testis: 2.1 gallbladder,kidney: 0.1 Not detected +ACP7 FLJ16165, PAPL, PAPL1 ENSG00000183760 Acid phosphatase 7, tartrate resistant (putative) 19 39083913-39111493 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042005, HPA042613 Uncertain Group enriched Group enriched 6 cerebral cortex: 1.8;skin: 6.9;tonsil: 2.3 epididymis,prostate: 0.5 Cell line enhanced hTEC/SVTERT24-B: 9.3;U-87 MG: 43.5 +KREMEN1 KREMEN, KRM1 ENSG00000183762 Kringle containing transmembrane protein 1 22 29073078-29168333 Predicted membrane proteins Evidence at protein level HPA058513 Approved Nucleoplasm
Nuclear bodies
Cytosol Not detected Mixed skin: 43.4 Cell line enhanced U-2197: 55.3 +TRAIP RNF206, TRIP ENSG00000183763 TRAF interacting protein 3 49828599-49856574 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036261, HPA036262 Enhanced Supported Plasma membrane
Cytosol Liver cancer:8.77e-5 (unfavourable) Expressed in all Mixed testis: 11.3 Mixed +CHEK2 bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53 ENSG00000183765 Checkpoint kinase 2 22 28687743-28742422 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA001878, CAB002030 Enhanced Supported Nucleoplasm
Golgi apparatus Renal cancer:7.80e-9 (unfavourable) Expressed in all Mixed testis: 13.4 Expressed in all +FOXL2 BPES, BPES1 ENSG00000183770 Forkhead box L2 3 138944224-138947140 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA069613 Enhanced Supported Nucleus
Cytokinetic bridge Mixed Tissue enhanced endometrium: 12.1;ovary: 29.6;parathyroid gland: 24.4 fallopian tube: 7.7 Cell line enhanced A-431: 4.3;fHDF/TERT166: 4.3;HEL: 7.2;hTCEpi: 5.1;K-562: 7.5;SiHa: 5.9 +AIFM3 AIFL, FLJ30473 ENSG00000183773 Apoptosis inducing factor, mitochondria associated 3 22 20965108-20981360 Predicted intracellular proteins Evidence at protein level HPA001271 Enhanced Mitochondria Urothelial cancer:7.13e-5 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 18.5;colon: 18.7 rectum: 9.0 Cell line enhanced Hep G2: 5.1;HMC-1: 9.5;T-47d: 5.0;THP-1: 5.1 +KCTD16 KIAA1317 ENSG00000183775 Potassium channel tetramerization domain containing 16 5 144170832-144485686 Predicted intracellular proteins Evidence at protein level HPA044590, HPA050154 Approved Approved Nuclear speckles Tissue enhanced Group enriched 7 cerebral cortex: 12.3;testis: 3.0 lung: 1.1 Cell line enhanced SCLC-21H: 5.4;TIME: 7.3 +B3GALT5 B3GalT-V, B3T5, beta3Gal-T5, GLCT5 ENSG00000183778 Beta-1,3-galactosyltransferase 5 21 39556442-39673137 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054092, HPA054684 Approved Endometrial cancer:6.36e-4 (favourable) Mixed Group enriched 5 colon: 22.7;duodenum: 27.5;gallbladder: 8.6;rectum: 40.5;small intestine: 37.2 stomach: 5.0 Group enriched 5 CAPAN-2: 20.6;NTERA-2: 6.3;RPTEC TERT1: 20.7;SCLC-21H: 5.4 +ZNF703 FLJ14299, NLZ1, ZEPPO1, ZNF503L, Zpo1 ENSG00000183779 Zinc finger protein 703 8 37695751-37700021 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023930, CAB068249 Supported Renal cancer:2.70e-7 (unfavourable) Expressed in all Mixed fallopian tube: 30.7 Cell line enhanced HEK 293: 142.2 +SLC35F3 FLJ37712 ENSG00000183780 Solute carrier family 35 member F3 1 233904933-234324516 Predicted membrane proteins, Transporters Evidence at protein level HPA051327, HPA061582 Uncertain Approved Nucleoli
Golgi apparatus Mixed Tissue enhanced cerebral cortex: 10.1 breast: 3.0 Cell line enriched 7 HDLM-2: 103.6 +KCTD8 ENSG00000183783 Potassium channel tetramerization domain containing 8 4 44173909-44448807 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031562 Enhanced Approved Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 11.5;thyroid gland: 5.2 testis: 2.4 Cell line enhanced HAP1: 2.2;NTERA-2: 1.5;SCLC-21H: 6.8;U-2 OS: 1.8 +C9orf66 FLJ31158 ENSG00000183784 Chromosome 9 open reading frame 66 9 212824-215741 Predicted intracellular proteins Evidence at transcript level HPA035652 Uncertain Renal cancer:1.32e-5 (favourable) Tissue enhanced Tissue enhanced kidney: 17.8 adrenal gland: 4.0 Cell line enhanced BEWO: 1.5;THP-1: 2.3 +TUBA8 TUBAL2 ENSG00000183785 Tubulin alpha 8 22 18110331-18146554 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043684, CAB046031, HPA063394 Approved Supported Microtubules Not detected Group enriched 6 cerebral cortex: 28.6;heart muscle: 83.0;skeletal muscle: 121.7;testis: 47.4 thyroid gland: 11.2 Group enriched 5 NB-4: 19.8;SCLC-21H: 17.4;TIME: 31.1 +ELOA3 ELOA3A, HsT829, TCEB3C, TCEB3L2 ENSG00000183791 Elongin A3 18 47028202-47030078 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048971, HPA049178, HPA050086 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +NPIPA5 ENSG00000183793 Nuclear pore complex interacting protein family member A5 16 15363624-15381047 Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Mixed Mixed testis: 17.2 Mixed +BPY2B VCY2B ENSG00000183795 Basic charge, Y-linked, 2B Y 24607560-24639207 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 11 testis: 2.1 gallbladder,kidney: 0.1 Not detected +EMILIN3 C20orf130, dJ620E11.4, EMILIN5 ENSG00000183798 Elastin microfibril interfacer 3 20 41359966-41366827 Predicted secreted proteins Evidence at protein level HPA044034, HPA059912 Approved Tissue enhanced Tissue enhanced epididymis: 65.0 seminal vesicle: 14.0 Group enriched 7 AF22: 6.2;HAP1: 11.4;NTERA-2: 7.0;SCLC-21H: 15.2 +OLFML1 UNQ564 ENSG00000183801 Olfactomedin like 1 11 7485388-7511377 Predicted secreted proteins Evidence at protein level HPA039735 Uncertain Renal cancer:4.28e-8 (unfavourable) Expressed in all Mixed ovary: 60.1 Group enriched 7 BEWO: 29.5;U-2197: 19.0 +FAM162B bA86F4.2, C6orf189 ENSG00000183807 Family with sequence similarity 162 member B 6 116752197-116765723 Predicted membrane proteins Evidence at protein level HPA036112, HPA060342 Enhanced Renal cancer:2.48e-4 (unfavourable) Tissue enriched Tissue enhanced placenta: 94.0 lung: 27.0 Cell line enhanced BJ: 7.3;BJ hTERT+: 19.0;BJ hTERT+ SV40 Large T+ RasG12V: 21.4;HSkMC: 5.6 +RBM12B ENSG00000183808 RNA binding motif protein 12B 8 93729356-93741017 Predicted intracellular proteins Evidence at protein level HPA024398, HPA053050 Uncertain Approved Nucleoplasm Expressed in all Expressed in all testis: 33.0 Mixed +CCR4 CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5 ENSG00000183813 C-C motif chemokine receptor 4 3 32951574-32956349 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA031613 Approved Mixed Tissue enhanced appendix: 11.5 urinary bladder: 8.9 Cell line enriched 17 HDLM-2: 187.8 +LIN9 TGS ENSG00000183814 Lin-9 DREAM MuvB core complex component 1 226231149-226309869 Predicted intracellular proteins Evidence at protein level HPA030241 Uncertain Supported Nucleoplasm Expressed in all Mixed testis: 16.9 Expressed in all +BTBD9 dJ322I12.1, KIAA1880 ENSG00000183826 BTB domain containing 9 6 38168451-38640148 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041930 Uncertain Approved Nucleoplasm Renal cancer:4.20e-13 (favourable) Expressed in all Mixed parathyroid gland: 38.3 Expressed in all +NUDT14 UGPP ENSG00000183828 Nudix hydrolase 14 14 105172938-105181323 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046755, HPA058759 Approved Approved Nucleoli
Microtubules Renal cancer:1.18e-5 (favourable), Ovarian cancer:1.66e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 24.7 Mixed +ANKRD45 CT117, FLJ45235 ENSG00000183831 Ankyrin repeat domain 45 1 173609561-173669862 Predicted intracellular proteins Evidence at protein level HPA031655, HPA031656, HPA031657 Enhanced Mixed Tissue enhanced fallopian tube: 35.0;parathyroid gland: 22.9;testis: 36.3 cerebral cortex: 7.2 Cell line enhanced AF22: 9.4;BJ hTERT+ SV40 Large T+ RasG12V: 5.0;SH-SY5Y: 9.1 +MAATS1 AAT1, AAT1alpha, C3orf15, CaM-IP2, SPATA26 ENSG00000183833 MYCBP associated and testis expressed 1 3 119703022-119767102 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced fallopian tube: 22.7;testis: 15.8 thyroid gland: 7.8 Cell line enhanced AF22: 1.7;RPTEC TERT1: 1.8;SCLC-21H: 4.2;SH-SY5Y: 2.7;T-47d: 1.7;U-87 MG: 1.8 +PNMA3 MA3, MA5, MGC132756, MGC132758 ENSG00000183837 Paraneoplastic Ma antigen 3 X 153056409-153060467 Predicted intracellular proteins Evidence at transcript level HPA047920 Approved Endometrial cancer:4.14e-5 (unfavourable) Mixed Group enriched 13 cerebral cortex: 15.4;epididymis: 45.4;testis: 12.3 fallopian tube: 1.8 Cell line enhanced NTERA-2: 3.2;SCLC-21H: 1.2 +GPR39 ENSG00000183840 G protein-coupled receptor 39 2 132416574-132646559 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA022111 Approved Pancreatic cancer:7.50e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 18.5 cervix, uterine,colon: 6.0 Cell line enhanced A-431: 25.5;hTEC/SVTERT24-B: 28.7 +FAM3B 2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44 ENSG00000183844 Family with sequence similarity 3 member B 21 41304212-41357431 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015885, HPA029777 Approved Approved Vesicles Tissue enhanced Tissue enhanced duodenum: 162.1;small intestine: 166.8 stomach: 124.0 Cell line enhanced CACO-2: 16.2;CAPAN-2: 10.8;Hep G2: 22.1;RPMI-8226: 62.5 +ZNF730 ENSG00000183850 Zinc finger protein 730 19 23075210-23147219 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Tissue enhanced testis: 9.3 ovary: 3.1 Cell line enhanced NTERA-2: 23.2;REH: 19.3 +KIRREL NEPH1 ENSG00000183853 Kin of IRRE like (Drosophila) 1 157993273-158100262 Predicted membrane proteins Evidence at protein level HPA030458 Approved Renal cancer:1.12e-8 (unfavourable), Cervical cancer:1.87e-4 (unfavourable), Urothelial cancer:2.85e-4 (unfavourable) Expressed in all Mixed placenta: 47.1 Cell line enhanced WM-115: 333.0 +IQGAP3 ENSG00000183856 IQ motif containing GTPase activating protein 3 1 156525405-156572604 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030142, HPA030143 Uncertain Approved Nucleus
Nucleoli Renal cancer:0.00e+0 (unfavourable), Liver cancer:8.94e-6 (unfavourable) Expressed in all Mixed bone marrow: 9.9 Mixed +CNGA2 CNCA, CNCA1, CNG2, FLJ46312, OCNC1, OCNCa, OCNCALPHA ENSG00000183862 Cyclic nucleotide gated channel alpha 2 X 151738451-151745304 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA015065 Uncertain Not detected Not detected testis: 0.4 Not detected +TOB2 APRO5, bK223H9, TOB4, TOBL, TROB2 ENSG00000183864 Transducer of ERBB2, 2 22 41433492-41447023 Predicted intracellular proteins Evidence at protein level HPA016603, HPA054112 Approved Approved Cytosol Renal cancer:1.18e-6 (favourable), Endometrial cancer:3.08e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 60.1 Expressed in all +SCN5A CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1 ENSG00000183873 Sodium voltage-gated channel alpha subunit 5 3 38548057-38649673 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Mixed Tissue enriched 18 heart muscle: 27.8 cervix, uterine: 1.5 Cell line enhanced LHCN-M2: 23.1;RH-30: 22.0 +ARSI FLJ16069, SPG66 ENSG00000183876 Arylsulfatase family member I 5 150296343-150339307 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038386, HPA038398 Uncertain Approved Golgi apparatus Urothelial cancer:1.19e-4 (unfavourable), Lung cancer:9.11e-4 (unfavourable) Mixed Mixed skin: 5.7 Cell line enhanced HaCaT: 27.7;hTEC/SVTERT24-B: 30.9;U-87 MG: 38.4 +UTY KDM6AL, KDM6C ENSG00000183878 Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked Y 13248379-13480673 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000568, HPA001165 Supported Approved Nucleoli Mixed Mixed prostate: 13.2 Cell line enhanced HEL: 18.6 +C1orf64 ERRF, MGC24047 ENSG00000183888 Chromosome 1 open reading frame 64 1 16004236-16008807 Predicted intracellular proteins Evidence at transcript level HPA026676 Uncertain Approved Nucleoplasm Endometrial cancer:1.68e-6 (favourable) Tissue enhanced Tissue enhanced breast: 6.8 cervix, uterine: 3.3 Group enriched 9 Hep G2: 5.3;SK-BR-3: 10.1;T-47d: 4.1 +AC138969.4 ENSG00000183889 16 16317444-16350590 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Not detected Expressed in all skin: 116.2 Expressed in all +TTC32 ENSG00000183891 Tetratricopeptide repeat domain 32 2 19896643-19901986 Predicted intracellular proteins Evidence at protein level HPA036024 Approved Approved Nucleoplasm
Mitochondria Renal cancer:5.45e-6 (unfavourable), Lung cancer:9.44e-4 (favourable) Expressed in all Expressed in all epididymis: 36.4 Expressed in all +LRRC55 FLJ45686 ENSG00000183908 Leucine rich repeat containing 55 11 57181747-57191717 Predicted membrane proteins, Transporters Evidence at protein level HPA014053 Uncertain Group enriched Tissue enhanced cerebral cortex: 6.6 lymph node: 2.4 Group enriched 33 AF22: 19.1;NTERA-2: 4.6 +DNAH2 DNHD3, FLJ46675, KIAA1503 ENSG00000183914 Dynein axonemal heavy chain 2 17 7717354-7833744 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067103 Enhanced Approved Microtubules Mixed Group enriched 8 fallopian tube: 20.9;parathyroid gland: 28.4;testis: 10.9 placenta: 2.5 Cell line enhanced A-431: 2.2;CACO-2: 3.2;CAPAN-2: 2.1;SCLC-21H: 2.7;SiHa: 2.4 +SH2D1A DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD ENSG00000183918 SH2 domain containing 1A X 124227868-124373197 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:4.94e-6 (unfavourable), Breast cancer:2.03e-4 (favourable) Mixed Tissue enhanced lymph node: 36.3;spleen: 17.5 tonsil: 13.2 Group enriched 6 HDLM-2: 89.9;Karpas-707: 148.7;MOLT-4: 209.2 +SDR42E2 ENSG00000183921 Short chain dehydrogenase/reductase family 42E, member 2 16 22165583-22191754 Predicted membrane proteins No evidence HPA061278 Uncertain Not detected Not detected testis: 0.2 Not detected +PRKX PKX1 ENSG00000183943 Protein kinase, X-linked X 3604370-3713608 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015324 Supported Supported Nucleus Expressed in all Tissue enhanced thyroid gland: 58.0 fallopian tube: 31.8 Cell line enhanced HMC-1: 67.0 +KMT5A PR-Set7, SET07, SET8, SETD8 ENSG00000183955 Lysine methyltransferase 5A 12 123383773-123409358 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA064495 Approved Nucleus
Cytosol Liver cancer:6.21e-7 (unfavourable) Expressed in all Expressed in all prostate: 36.8 Expressed in all +KCNH8 elk3, Kv12.1 ENSG00000183960 Potassium voltage-gated channel subfamily H member 8 3 19148454-19535646 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA016586 Supported Plasma membrane Mixed Tissue enhanced cerebral cortex: 4.8 adrenal gland: 2.3 Cell line enhanced HAP1: 1.0;SH-SY5Y: 4.4 +SMTN ENSG00000183963 Smoothelin 22 31064105-31104757 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001721, HPA051778, HPA058590 Enhanced Enhanced Nucleoplasm
Actin filaments Renal cancer:2.73e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 251.4 Expressed in all +NPW PPL8 ENSG00000183971 Neuropeptide W 16 2009926-2020755 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA064874 Approved Mixed Tissue enhanced liver: 5.2;stomach: 2.9 epididymis: 1.7 Cell line enhanced NB-4: 29.9;RPMI-8226: 57.2;SCLC-21H: 161.6 +PP2D1 C3orf48, FLJ25449 ENSG00000183977 Protein phosphatase 2C like domain containing 1 3 19979961-20012330 Predicted intracellular proteins Evidence at protein level HPA036870, HPA066083 Supported Uncertain Nucleoplasm
Intermediate filaments Not detected Tissue enriched 11 testis: 12.8 bone marrow: 1.1 Not detected +COA3 CCDC56, COX25, HSPC009, MITRAC12 ENSG00000183978 Cytochrome c oxidase assembly factor 3 17 42795147-42798704 Predicted membrane proteins Evidence at protein level HPA031966 Approved Supported Mitochondria Cervical cancer:3.40e-4 (favourable), Renal cancer:6.62e-4 (favourable), Endometrial cancer:8.93e-4 (favourable) Expressed in all Expressed in all epididymis: 213.9 Expressed in all +NPB PPL7, PPNPB ENSG00000183979 Neuropeptide B 17 81900745-81902905 Predicted secreted proteins Evidence at protein level Not detected Not detected cerebral cortex: 0.6 Cell line enhanced PC-3: 2.3;RH-30: 1.8;SH-SY5Y: 2.2;U-2 OS: 2.4 +ST6GALNAC3 SIAT7C ENSG00000184005 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 1 76074719-76634601 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054566, HPA055399 Uncertain Supported Nucleoplasm Mixed Tissue enhanced thyroid gland: 22.4 parathyroid gland: 11.1 Cell line enhanced AF22: 35.4;HUVEC TERT2: 38.4;SK-MEL-30: 49.6;TIME: 16.7 +PTP4A2 HU-PP-1, OV-1, PRL-2, ptp-IV1a, PTP4A, PTPCAAX2 ENSG00000184007 Protein tyrosine phosphatase type IVA, member 2 1 31906421-31944856 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003281, CAB011204 Uncertain Renal cancer:5.10e-11 (unfavourable), Liver cancer:2.62e-5 (unfavourable), Urothelial cancer:2.72e-5 (favourable) Expressed in all Expressed in all thyroid gland: 283.0 Expressed in all +ACTG1 ACTG, DFNA20, DFNA26 ENSG00000184009 Actin gamma 1 17 81509971-81523847 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041264, HPA041271 Approved Colorectal cancer:2.41e-4 (favourable) Expressed in all Expressed in all ovary: 2397.0 Expressed in all +TMPRSS2 PRSS10 ENSG00000184012 Transmembrane protease, serine 2 21 41464551-41531116 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034493, HPA035787 Enhanced Supported Nucleoplasm
Cell Junctions Renal cancer:7.86e-6 (favourable), Endometrial cancer:2.56e-4 (favourable) Tissue enriched Tissue enhanced prostate: 489.3 stomach: 142.6 Cell line enhanced CACO-2: 21.8;RT4: 50.4;SK-BR-3: 9.5 +DENND5A FLJ22354, FLJ33829, FLJ43455, KIAA1091, RAB6IP1 ENSG00000184014 DENN domain containing 5A 11 9138825-9265390 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052923, HPA055009 Uncertain Approved Golgi apparatus
Vesicles Renal cancer:1.14e-6 (unfavourable), Liver cancer:5.05e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 126.7 Mixed +OR2T10 ENSG00000184022 Olfactory receptor family 2 subfamily T member 10 1 248592830-248593768 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA052019 Uncertain Tissue enhanced Tissue enriched 18 kidney: 7.1 prostate: 0.3 Not detected +DSCR4 DCRB ENSG00000184029 Down syndrome critical region 4 21 37951425-38121360 Predicted intracellular proteins Evidence at transcript level HPA018460 Uncertain Tissue enriched Group enriched 18 placenta: 2.0;testis: 1.4 all non-specific tissues: 0.0 Cell line enhanced BEWO: 5.8;K-562: 9.1;RPMI-8226: 3.0;U-266/70: 5.5;U-266/84: 3.9 +KRTAP20-2 KAP20.2 ENSG00000184032 Keratin associated protein 20-2 21 30635236-30635619 Predicted intracellular proteins No evidence Not detected Not detected skin: 0.6 Not detected +CTAG1B CT6.1, CTAG, CTAG1, ESO1, LAGE2A, LAGE2B, NY-ESO-1 ENSG00000184033 Cancer/testis antigen 1B X 154617609-154619282 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB015453 Enhanced Not detected Tissue enriched 55 testis: 5.4 all non-specific tissues: 0.0 Group enriched 1072 U-266/70: 579.6;U-266/84: 139.5 +DIABLO DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC ENSG00000184047 Diablo IAP-binding mitochondrial protein 12 122207662-122227534 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001825, CAB003857, CAB016688 Enhanced Enhanced Mitochondria Renal cancer:5.35e-4 (unfavourable) Expressed in all Expressed in all testis: 94.9 Expressed in all +VPS33B FLJ14848 ENSG00000184056 VPS33B, late endosome and lysosome associated 15 90998416-91022603 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040415 Approved Expressed in all Expressed in all cerebral cortex: 16.1 Expressed in all +TBX1 CATCH22, VCF ENSG00000184058 T-box 1 22 19756703-19783593 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029330 Approved Nuclear bodies
Cytoplasmic bodies Urothelial cancer:8.90e-4 (favourable) Mixed Tissue enhanced skeletal muscle: 23.0 testis: 10.5 Cell line enhanced K-562: 107.3;TIME: 35.1 +ADAP2 CENTA2 ENSG00000184060 ArfGAP with dual PH domains 2 17 30906344-30959322 Predicted intracellular proteins Evidence at protein level Renal cancer:2.36e-6 (unfavourable), Liver cancer:3.12e-4 (unfavourable), Head and neck cancer:3.97e-4 (favourable), Colorectal cancer:5.62e-4 (unfavourable) Expressed in all Mixed spleen: 29.3 Cell line enhanced HAP1: 17.5;HEK 293: 9.1;RPMI-8226: 15.4 +UQCR10 HSPC051, QCR9, UCCR7.2, UCRC ENSG00000184076 Ubiquinol-cytochrome c reductase, complex III subunit X 22 29767369-29770413 Predicted membrane proteins Evidence at protein level Renal cancer:5.45e-5 (favourable) Expressed in all Expressed in all heart muscle: 205.9 Expressed in all +FAM120C CXorf17, FLJ20506, ORF34 ENSG00000184083 Family with sequence similarity 120C X 54068324-54183281 Predicted intracellular proteins Evidence at protein level HPA047677 Uncertain Approved Nuclear speckles Head and neck cancer:4.48e-4 (favourable) Expressed in all Mixed cerebral cortex: 9.6 Expressed in all +TRIML1 FLJ36180, RNF209 ENSG00000184108 Tripartite motif family like 1 4 188139419-188147743 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 147 testis: 14.7 all non-specific tissues: 0.0 Cell line enriched 12 BEWO: 1.5 +EIF3C eIF3-p110, eIF3c, EIF3S8 ENSG00000184110 Eukaryotic translation initiation factor 3 subunit C 16 28688558-28735730 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034045, HPA047097, HPA049495, HPA050112 Supported Supported Cytosol Expressed in all Expressed in all parathyroid gland: 571.3 Expressed in all +CLDN5 AWAL, BEC1, CPETRL1, TMVCF ENSG00000184113 Claudin 5 22 19523024-19527545 Predicted membrane proteins, Transporters Evidence at protein level CAB002607 Approved Expressed in all Tissue enhanced adipose tissue: 128.2 lung: 53.4 Group enriched 12 HUVEC TERT2: 71.6;SCLC-21H: 62.4 +NIPSNAP1 ENSG00000184117 Nipsnap homolog 1 22 29554808-29581337 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059227 Uncertain Renal cancer:8.82e-6 (favourable) Expressed in all Expressed in all liver: 134.2 Expressed in all +OR4F6 OR4F12 ENSG00000184140 Olfactory receptor family 4 subfamily F member 6 15 101805699-101806686 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +CNTN2 AXT, TAG-1, TAX, TAX1 ENSG00000184144 Contactin 2 1 205042937-205078284 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA001397, HPA012497 Approved Tissue enriched Tissue enriched 7 cerebral cortex: 81.7 testis: 11.2 Group enriched 7 NTERA-2: 3.8;SCLC-21H: 11.1 +SPRR4 ENSG00000184148 Small proline rich protein 4 1 152970666-152972574 Predicted intracellular proteins Evidence at protein level HPA055963 Enhanced Tissue enhanced Tissue enriched 6 skin: 48.3 breast: 7.8 Not detected +LRTOMT CFAP111, COMT2, DFNB63, LRRC51 ENSG00000184154 Leucine rich transmembrane and O-methyltransferase domain containing 11 72080331-72110782 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039949 Approved Approved Nucleoli
Microtubules Ovarian cancer:5.36e-4 (favourable), Endometrial cancer:7.70e-4 (favourable) Expressed in all Expressed in all testis: 136.6 Expressed in all +OR10J5 ENSG00000184155 Olfactory receptor family 10 subfamily J member 5 1 159535078-159536007 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +KCNQ3 EBN2, Kv7.3 ENSG00000184156 Potassium voltage-gated channel subfamily Q member 3 8 132120858-132481019 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Mixed Tissue enriched 14 cerebral cortex: 26.7 adrenal gland: 1.9 Cell line enhanced hTERT-HME1: 5.1;U-2 OS: 4.5;U-87 MG: 3.5 +ADRA2C ADRA2L2, ADRA2RL2, ADRARL2 ENSG00000184160 Adrenoceptor alpha 2C 4 3766348-3768526 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA057688 Uncertain Mixed Tissue enhanced cervix, uterine: 20.9;endometrium: 26.0;seminal vesicle: 26.8 fallopian tube: 7.9 Cell line enhanced Hep G2: 9.0;MCF7: 16.8;SCLC-21H: 9.5;SH-SY5Y: 10.3 +NR2C2AP TRA16 ENSG00000184162 Nuclear receptor 2C2 associated protein 19 19201416-19203424 Predicted intracellular proteins Evidence at protein level HPA042054, HPA055653 Approved Enhanced Nucleoplasm Liver cancer:5.63e-5 (unfavourable), Thyroid cancer:1.65e-4 (favourable), Colorectal cancer:8.53e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 24.0 Expressed in all +C1QTNF12 ADIPOLIN, C1QDC2, CTRP12, FAM132A, MGC105127 ENSG00000184163 C1q and tumor necrosis factor related protein 12 1 1242446-1246722 Predicted secreted proteins Evidence at protein level HPA024107 Approved Approved Vesicles Mixed Tissue enhanced duodenum: 6.9;small intestine: 7.3 colon: 2.1 Group enriched 5 EFO-21: 3.9;U-2 OS: 4.3 +CRELD2 MGC11256 ENSG00000184164 Cysteine rich with EGF like domains 2 22 49918167-49927540 Predicted secreted proteins Evidence at protein level HPA000603, CAB025604 Approved Renal cancer:1.34e-9 (unfavourable), Endometrial cancer:2.42e-7 (favourable) Expressed in all Expressed in all thyroid gland: 94.2 Expressed in all +OR1D2 OLFR1, OR17-4 ENSG00000184166 Olfactory receptor family 1 subfamily D member 2 17 3092058-3092996 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected testis: 0.1 Not detected +SCFD2 FLJ39514, STXBP1L1 ENSG00000184178 Sec1 family domain containing 2 4 52872982-53366075 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036526, HPA036527 Enhanced Approved Nucleus Renal cancer:3.81e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 14.7 Expressed in all +UBE2F NCE2 ENSG00000184182 Ubiquitin conjugating enzyme E2 F (putative) 2 237966827-238042782 Predicted intracellular proteins Evidence at protein level HPA037444 Approved Approved Cytosol Renal cancer:1.59e-7 (unfavourable), Liver cancer:2.72e-4 (unfavourable) Expressed in all Expressed in all epididymis: 64.0 Expressed in all +KCNJ12 hIRK1, IRK2, KCNJN1, Kir2.2, Kir2.2v ENSG00000184185 Potassium voltage-gated channel subfamily J member 12 17 21376197-21419872 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA027021 Approved Uncertain Nucleoplasm
Golgi apparatus
Cytosol Endometrial cancer:7.84e-5 (unfavourable) Mixed Group enriched 5 parathyroid gland: 19.2;skeletal muscle: 23.1 heart muscle: 3.9 Cell line enhanced HeLa: 2.6;PC-3: 3.9;SCLC-21H: 5.6;SiHa: 2.6;U-2197: 3.9 +GPR173 SREB3 ENSG00000184194 G protein-coupled receptor 173 X 53049091-53080615 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA003905 Approved Plasma membrane
Cytosol Endometrial cancer:2.88e-6 (unfavourable), Pancreatic cancer:2.33e-5 (favourable), Renal cancer:2.47e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 19.1 ovary: 8.9 Cell line enhanced HAP1: 10.2 +PPP1R2 IPP2 ENSG00000184203 Protein phosphatase 1 regulatory inhibitor subunit 2 3 195514425-195543386 Predicted intracellular proteins Evidence at protein level HPA043729, HPA059420 Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 52.4 Expressed in all +TSPYL2 CDA1, CINAP, CTCL, DENTT, HRIHFB2216, SE20-4, TSPX ENSG00000184205 TSPY like 2 X 53082367-53088540 Predicted intracellular proteins Evidence at protein level HPA044133 Approved Pancreatic cancer:6.74e-8 (favourable), Renal cancer:8.16e-7 (unfavourable), Colorectal cancer:3.23e-4 (unfavourable) Expressed in all Expressed in all ovary: 144.3 Expressed in all +GOLGA6L4 ENSG00000184206 Golgin A6 family-like 4 15 84235773-84245368 Predicted intracellular proteins Evidence at transcript level Not detected Mixed ovary: 7.5 Mixed +PGP ENSG00000184207 Phosphoglycolate phosphatase 16 2211997-2214807 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043096, HPA046739 Approved Approved Nuclear bodies Urothelial cancer:6.42e-4 (favourable), Renal cancer:7.05e-4 (favourable) Expressed in all Expressed in all testis: 28.1 Expressed in all +C22orf46 CTA-216E10.6, FLJ23584 ENSG00000184208 Chromosome 22 open reading frame 46 22 41688939-41698136 Predicted secreted proteins Evidence at transcript level HPA052741 Uncertain Approved Nucleus
Nucleoli Endometrial cancer:4.70e-4 (favourable) Expressed in all Mixed parathyroid gland: 17.3 Expressed in all +SNRNP35 U1SNRNPBP ENSG00000184209 Small nuclear ribonucleoprotein U11/U12 subunit 35 12 123457641-123473154 Predicted intracellular proteins Evidence at protein level HPA059145, HPA067031 Supported Supported Nucleoli Expressed in all Expressed in all parathyroid gland: 34.2 Expressed in all +DGAT2L6 DC3, FLJ25989 ENSG00000184210 Diacylglycerol O-acyltransferase 2 like 6 X 70177483-70205545 Predicted membrane proteins Evidence at transcript level Tissue enhanced Group enriched 22 breast: 2.8;skin: 1.6 all non-specific tissues: 0.0 Not detected +IRAK1 IRAK, pelle ENSG00000184216 Interleukin 1 receptor associated kinase 1 X 154010500-154019980 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004461, HPA054476 Supported Supported Nucleus
Cytosol Renal cancer:2.06e-4 (unfavourable), Liver cancer:3.03e-4 (unfavourable) Expressed in all Expressed in all appendix: 51.0 Expressed in all +CMSS1 C3orf26, MGC4308 ENSG00000184220 Cms1 ribosomal small subunit homolog (yeast) 3 99817834-100181732 Predicted intracellular proteins Evidence at protein level HPA042820 Uncertain Approved Nucleus
Nuclear membrane
Nucleoli
Mitochondria Liver cancer:5.92e-10 (unfavourable), Endometrial cancer:3.15e-6 (unfavourable), Prostate cancer:3.10e-4 (unfavourable) Expressed in all Expressed in all testis: 53.1 Expressed in all +OLIG1 BHLHB6, bHLHe21 ENSG00000184221 Oligodendrocyte transcription factor 1 21 33070144-33072420 Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enriched Tissue enriched 104 cerebral cortex: 142.6 kidney: 1.3 Cell line enhanced NB-4: 24.7;RPMI-8226: 14.1;THP-1: 17.1;U-937: 22.7 +PCDH9 ENSG00000184226 Protocadherin 9 13 66302834-67230445 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA015581 Approved Nucleoplasm
Centrosome Tissue enriched Tissue enriched 11 cerebral cortex: 68.8 seminal vesicle: 6.1 Cell line enhanced AF22: 24.9;LHCN-M2: 34.9;TIME: 40.1;U-698: 44.9 +ACOT1 ACH2, CTE-1, LACH2 ENSG00000184227 Acyl-CoA thioesterase 1 14 73537114-73543794 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043705 Approved Approved Mitochondria Renal cancer:5.09e-8 (favourable) Expressed in all Mixed smooth muscle: 29.4 Cell line enhanced T-47d: 35.8 +OAF MGC52117 ENSG00000184232 Out at first homolog 11 120210767-120230332 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA047412 Uncertain Approved Nucleus Head and neck cancer:5.71e-5 (unfavourable) Expressed in all Expressed in all liver: 80.2 Cell line enhanced Hep G2: 127.6 +ALDH1A3 ALDH6, RALDH3 ENSG00000184254 Aldehyde dehydrogenase 1 family member A3 15 100877714-100916626 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046271, HPA064749 Enhanced Enhanced Nucleus
Cytosol Group enriched Tissue enhanced prostate: 217.5 adipose tissue: 74.8 Cell line enhanced HaCaT: 383.6;HBEC3-KT: 772.3;U-2197: 565.6;U-87 MG: 467.6;WM-115: 498.3 +CDR1 CDR, CDR34, CDR62A ENSG00000184258 Cerebellar degeneration related protein 1 X 140782405-140784871 Predicted intracellular proteins Evidence at protein level HPA073147 Approved Nucleoplasm
Golgi apparatus
Centrosome Not detected Group enriched 7 cerebral cortex: 48.4;skin: 12.1 adipose tissue: 4.0 Cell line enhanced BJ: 6.3;U-87 MG: 26.1 +HIST2H2AC H2A, H2A/q, H2AFQ ENSG00000184260 Histone cluster 2 H2A family member c 1 149886975-149887364 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Renal cancer:1.20e-10 (unfavourable), Urothelial cancer:7.86e-5 (favourable) Expressed in all Tissue enriched 10 bone marrow: 23.8 adrenal gland: 2.4 Cell line enhanced MCF7: 73.2 +KCNK12 K2p12.1, THIK-2, THIK2 ENSG00000184261 Potassium two pore domain channel subfamily K member 12 2 47516581-47570939 Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level Tissue enriched Tissue enriched 17 cerebral cortex: 5.3 placenta,testis: 0.3 Group enriched 6 REH: 21.5;SCLC-21H: 10.5 +HIST2H2AB ENSG00000184270 Histone cluster 2 H2A family member b 1 149887524-149887916 Predicted intracellular proteins Evidence at protein level CAB011483, HPA041189 Supported Approved Nucleus Mixed Tissue enriched 8 bone marrow: 4.0 prostate: 0.5 Cell line enhanced MOLT-4: 3.4 +POU6F1 BRN5, MPOU, TCFB1 ENSG00000184271 POU class 6 homeobox 1 12 51186936-51217708 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047021, HPA050411 Enhanced Supported Nuclear bodies
Actin filaments Pancreatic cancer:6.61e-4 (favourable) Expressed in all Mixed cerebral cortex: 10.9 Mixed +DEFB108B ENSG00000184276 Defensin beta 108B 11 71833200-71837710 Predicted secreted proteins Evidence at transcript level HPA042588 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +TM2D3 BLP2, FLJ22604 ENSG00000184277 TM2 domain containing 3 15 101621444-101652391 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054064 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 97.2 Expressed in all +TSSC4 ENSG00000184281 Tumor suppressing subtransferable candidate 4 11 2400488-2403878 Predicted intracellular proteins Evidence at protein level HPA041801, HPA058763 Approved Approved Nucleoplasm
Cytosol Liver cancer:9.91e-4 (unfavourable) Expressed in all Expressed in all testis: 56.5 Expressed in all +TACSTD2 EGP-1, GA733-1, M1S1, TROP2 ENSG00000184292 Tumor-associated calcium signal transducer 2 1 58575423-58577773 Disease related genes, Predicted membrane proteins Evidence at protein level HPA043104, HPA055067, CAB072852 Enhanced Supported Nucleoli
Vesicles
Plasma membrane Renal cancer:3.99e-4 (favourable) Mixed Tissue enhanced esophagus: 313.8 skin: 209.6 Cell line enhanced A-431: 502.8;CAPAN-2: 665.4;HaCaT: 672.0 +CLECL1 DCAL1 ENSG00000184293 C-type lectin like 1 12 9715860-9733299 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced lymph node: 28.7;spleen: 22.6;tonsil: 28.3 appendix: 13.3 Group enriched 5 HEL: 44.5;Karpas-707: 47.7;U-698: 120.2;U-937: 75.2 +SIX6 OPTX2, Six9 ENSG00000184302 SIX homeobox 6 14 60508951-60512850 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001403 Approved Approved Nucleoplasm Tissue enriched Not detected testis: 0.1 Cell line enriched 14 MOLT-4: 33.0 +PRKD1 PKC-mu, PKCM, PKD, PRKCM ENSG00000184304 Protein kinase D1 14 29576479-30191898 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB018367, HPA029834 Uncertain Supported Plasma membrane
Cytosol Renal cancer:2.44e-5 (favourable), Thyroid cancer:2.91e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 50.3 prostate: 28.5 Mixed +CCSER1 FAM190A, KIAA1680 ENSG00000184305 Coiled-coil serine rich protein 1 4 90127535-91601913 Predicted intracellular proteins Evidence at transcript level HPA041880, HPA054709 Uncertain Mixed Tissue enhanced testis: 4.6 adrenal gland: 1.7 Cell line enhanced HDLM-2: 1.4;RT4: 1.0;SCLC-21H: 1.5 +ZDHHC23 MGC42530 ENSG00000184307 Zinc finger DHHC-type containing 23 3 113947901-113965401 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016808 Uncertain Approved Nucleus Renal cancer:1.48e-7 (favourable), Endometrial cancer:2.85e-4 (unfavourable), Thyroid cancer:5.90e-4 (unfavourable) Expressed in all Mixed testis: 22.5 Mixed +MROH7 C1orf175, FLJ46354, HEATR8 ENSG00000184313 Maestro heat like repeat family member 7 1 54641754-54710266 Predicted intracellular proteins Evidence at protein level HPA071840 Enhanced Not detected Tissue enriched 30 testis: 49.5 ovary: 1.6 Not detected +OR51J1 OR51J1P, OR51J2 ENSG00000184321 Olfactory receptor family 51 subfamily J member 1 (gene/pseudogene) 11 5402597-5403547 G-protein coupled receptors, Predicted membrane proteins No evidence HPA017605 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +S100A7A S100A15, S100A7f, S100A7L1 ENSG00000184330 S100 calcium binding protein A7A 1 153416524-153423225 Predicted intracellular proteins Evidence at protein level HPA006997 Supported Tissue enhanced Group enriched 14 skin: 1.9;tonsil: 5.4 esophagus,testis: 0.2 Not detected +SRPK3 MSSK1, STK23 ENSG00000184343 SRSF protein kinase 3 X 153776412-153785732 Enzymes, Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced heart muscle: 28.7;skeletal muscle: 73.6 prostate: 10.9 Cell line enhanced RH-30: 45.4 +GDF3 ENSG00000184344 Growth differentiation factor 3 12 7689782-7695776 Disease related genes, Predicted secreted proteins Evidence at protein level HPA018468 Uncertain Tissue enriched Tissue enhanced kidney: 1.1;spleen: 1.1 testis: 0.8 Cell line enriched 14 NTERA-2: 450.4 +IQCF2 ENSG00000184345 IQ motif containing F2 3 51861629-51863424 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 96 testis: 9.6 all non-specific tissues: 0.0 Not detected +SLIT3 MEGF5, SLIL2, Slit-3, SLIT1, slit2 ENSG00000184347 Slit guidance ligand 3 5 168661733-169301129 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051630 Approved Supported Cell Junctions Renal cancer:2.45e-5 (unfavourable) Mixed Mixed parathyroid gland: 99.9 Cell line enhanced ASC diff: 212.7;fHDF/TERT166: 89.9;RT4: 80.4;SH-SY5Y: 77.7 +EFNA5 AF1, EPLG7, LERK7 ENSG00000184349 Ephrin A5 5 107376889-107670895 Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level CAB013282, HPA054047 Approved Approved Vesicles
Cytosol Renal cancer:1.92e-7 (unfavourable), Stomach cancer:3.77e-4 (unfavourable) Mixed Mixed cervix, uterine: 17.1 Cell line enhanced RPTEC TERT1: 43.4 +MRGPRE GPR167, mrgE ENSG00000184350 MAS related GPR family member E 11 3227698-3232386 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA046556 Uncertain Tissue enhanced Tissue enhanced cervix, uterine: 1.0 endometrium: 0.7 Cell line enhanced RPMI-8226: 1.5;SCLC-21H: 4.1 +KRTAP19-1 KAP19.1 ENSG00000184351 Keratin associated protein 19-1 21 30479699-30480344 Predicted intracellular proteins Evidence at transcript level Tissue enriched Not detected all non-specific tissues: 0.0 Cell line enriched 13 HEK 293: 19.8 +HIST1H1B H1.5, H1b, H1F5, H1s-3 ENSG00000184357 Histone cluster 1 H1 family member b 6 27866849-27867529 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012241, HPA055907 Approved Supported Nucleoplasm Tissue enhanced Tissue enhanced bone marrow: 6.2;lymph node: 2.6 urinary bladder: 0.9 Cell line enhanced MOLT-4: 8.9 +SPATA32 AEP2, C17orf46, FLJ25414, TEX34, VAD1.2 ENSG00000184361 Spermatogenesis associated 32 17 45254393-45262112 Predicted intracellular proteins Evidence at protein level HPA024549 Approved Not detected Tissue enriched 86 testis: 40.7 duodenum: 0.4 Cell line enhanced A549: 1.1 +PKP3 ENSG00000184363 Plakophilin 3 11 392614-404908 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012993, HPA062937 Enhanced Enhanced Nucleoplasm
Cell Junctions
Cytosol Lung cancer:2.89e-5 (unfavourable), Renal cancer:1.08e-4 (unfavourable), Pancreatic cancer:3.93e-4 (unfavourable) Mixed Tissue enhanced esophagus: 98.2;skin: 148.2 duodenum: 31.4 Cell line enhanced A-431: 131.6;HaCaT: 174.9;SK-BR-3: 111.1 +MAP7D2 FLJ14503 ENSG00000184368 MAP7 domain containing 2 X 20006713-20116917 Predicted intracellular proteins Evidence at protein level HPA051508, HPA059537 Enhanced Approved Nucleoplasm
Cytosol Renal cancer:7.27e-5 (unfavourable) Mixed Tissue enhanced cerebral cortex: 49.2;epididymis: 45.6 testis: 18.3 Cell line enhanced A549: 12.0;CACO-2: 16.0;HEK 293: 23.8;HeLa: 15.1;SCLC-21H: 34.5;SiHa: 13.5 +CSF1 M-CSF, MCSF, MGC31930 ENSG00000184371 Colony stimulating factor 1 1 109910242-109930992 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Renal cancer:1.00e-11 (unfavourable), Liver cancer:4.25e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 66.6 Cell line enhanced ASC diff: 146.1;HHSteC: 271.2;HSkMC: 150.5 +COLEC10 CL-L1 ENSG00000184374 Collectin subfamily member 10 8 118995452-119106582 Plasma proteins, Predicted secreted proteins Evidence at protein level Liver cancer:5.79e-4 (favourable) Mixed Group enriched 8 liver: 51.2;placenta: 26.0 thyroid gland: 5.0 Group enriched 6 BJ hTERT+: 5.2;HHSteC: 2.1;SK-BR-3: 8.4 +ACTRT3 ARPM1 ENSG00000184378 Actin related protein T3 3 169766921-169769895 Predicted intracellular proteins Evidence at protein level HPA035817, HPA035818 Approved Approved Nucleoplasm Endometrial cancer:4.11e-4 (unfavourable) Mixed Tissue enriched 22 testis: 60.6 fallopian tube: 2.7 Cell line enhanced ASC diff: 10.2 +PLA2G6 iPLA2, iPLA2beta, NBIA2, PARK14, PNPLA9 ENSG00000184381 Phospholipase A2 group VI 22 38111495-38205690 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level HPA001171 Approved Approved Microtubule organizing center
Cytosol Urothelial cancer:1.55e-4 (favourable), Cervical cancer:7.29e-4 (favourable) Expressed in all Expressed in all testis: 60.2 Cell line enhanced HEL: 55.1 +MAML2 KIAA1819, MAM3 ENSG00000184384 Mastermind like transcriptional coactivator 2 11 95976598-96343180 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035223 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:1.90e-4 (favourable), Pancreatic cancer:3.89e-4 (unfavourable) Expressed in all Mixed placenta: 17.5 Cell line enhanced HDLM-2: 48.9 +PABPC1L2B RBM32B ENSG00000184388 Poly(A) binding protein cytoplasmic 1 like 2B X 73003517-73005713 Predicted intracellular proteins Evidence at transcript level HPA041573 Approved Tissue enriched Group enriched 5 cerebral cortex: 8.7;prostate: 4.6 testis: 1.2 Cell line enhanced NTERA-2: 1.6 +A3GALT2 A3GALT2P, IGB3S, IGBS3S ENSG00000184389 Alpha 1,3-galactosyltransferase 2 1 33306766-33321098 Enzymes, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.6 Not detected +OR4N5 ENSG00000184394 Olfactory receptor family 4 subfamily N member 5 14 20143736-20144662 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 71 HEL: 7.0 +SS18L1 CREST, KIAA0693 ENSG00000184402 SS18L1, nBAF chromatin remodeling complex subunit 20 62143795-62182484 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB011827, HPA059046 Approved Supported Nucleoplasm
Cytosol Head and neck cancer:8.00e-5 (favourable), Lung cancer:3.74e-4 (favourable) Expressed in all Expressed in all skin: 23.7 Expressed in all +KCND2 KIAA1044, Kv4.2, RK5 ENSG00000184408 Potassium voltage-gated channel subfamily D member 2 7 120273668-120750331 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA029068 Approved Tissue enhanced Tissue enhanced cerebral cortex: 20.7 gallbladder: 6.8 Cell line enhanced ASC TERT1: 3.5;SCLC-21H: 15.6 +TOP1MT ENSG00000184428 Topoisomerase (DNA) I, mitochondrial 8 143304384-143359979 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA001915, HPA021542 Approved Supported Mitochondria Renal cancer:1.52e-7 (unfavourable) Expressed in all Expressed in all testis: 41.2 Expressed in all +COPB2 beta'-COP, betaprime-COP ENSG00000184432 Coatomer protein complex subunit beta 2 3 139355600-139389732 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036867, HPA058180 Approved Approved Cytosol Liver cancer:2.41e-7 (unfavourable), Pancreatic cancer:1.45e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 173.0 Expressed in all +LRRC19 FLJ21302 ENSG00000184434 Leucine rich repeat containing 19 9 26993136-27005693 Predicted membrane proteins Evidence at protein level Renal cancer:7.08e-8 (favourable) Group enriched Group enriched 9 colon: 35.9;duodenum: 23.7;gallbladder: 9.4;kidney: 45.1;rectum: 35.3;small intestine: 34.7 appendix: 3.5 Not detected +THAP7 MGC10963 ENSG00000184436 THAP domain containing 7 22 20999104-21002196 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003083 Approved Approved Nucleus
Vesicles Expressed in all Expressed in all testis: 20.4 Expressed in all +KNTC1 KIAA0166, ROD ENSG00000184445 Kinetochore associated 1 12 122527246-122626396 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025241 Approved Supported Plasma membrane
Cytosol Renal cancer:7.89e-8 (unfavourable), Liver cancer:4.79e-6 (unfavourable), Head and neck cancer:8.69e-4 (favourable) Expressed in all Tissue enhanced testis: 43.4 bone marrow: 27.1 Expressed in all +CCR10 GPR2 ENSG00000184451 C-C motif chemokine receptor 10 17 42678889-42683917 Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011684, HPA048007, HPA069188 Uncertain Supported Endoplasmic reticulum Mixed Mixed adipose tissue: 4.4 Cell line enhanced Karpas-707: 6.0;U-266/70: 13.0 +NCMAP C1orf130, FLJ42528, MP11 ENSG00000184454 Non-compact myelin associated protein 1 24556111-24609328 Predicted membrane proteins Evidence at transcript level HPA013656 Uncertain Endometrial cancer:2.83e-6 (favourable) Mixed Tissue enhanced gallbladder: 11.5 thyroid gland: 7.1 Cell line enhanced A549: 1.8;T-47d: 3.7;U-266/70: 2.3 +BPIFC BPIL2, dJ149A16.7 ENSG00000184459 BPI fold containing family C 22 32413847-32464484 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA037665, HPA043306 Uncertain Group enriched Tissue enriched 18 skin: 75.6 breast: 4.1 Cell line enhanced SCLC-21H: 1.5 +WDR27 MGC43690 ENSG00000184465 WD repeat domain 27 6 169457212-169702048 Predicted intracellular proteins Evidence at protein level HPA037497, HPA037498 Uncertain Enhanced Nucleoplasm Renal cancer:1.78e-5 (unfavourable) Expressed in all Mixed testis: 15.8 Expressed in all +TXNRD2 TR, TR3, TRXR2 ENSG00000184470 Thioredoxin reductase 2 22 19875517-19941992 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002007, HPA003323 Supported Supported Mitochondria
Cytosol Renal cancer:1.10e-7 (favourable) Expressed in all Expressed in all adrenal gland: 34.3 Expressed in all +C1QTNF8 CTRP8, UNQ5829 ENSG00000184471 C1q and tumor necrosis factor related protein 8 16 1090005-1096244 Predicted secreted proteins Evidence at protein level HPA056438 Uncertain Not detected Not detected fallopian tube: 0.7 Not detected +OR56A3 OR56A3P, OR56A6 ENSG00000184478 Olfactory receptor family 56 subfamily A member 3 11 5947340-5948361 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.1 Not detected +FOXO4 AFX1, MLLT7 ENSG00000184481 Forkhead box O4 X 71096197-71103535 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level HPA039560, HPA040232 Approved Supported Nuclear speckles
Cytosol Renal cancer:3.46e-4 (favourable), Head and neck cancer:4.61e-4 (favourable) Expressed in all Expressed in all placenta: 172.7 Cell line enriched 8 BEWO: 154.9 +POU3F2 BRN2, OCT7, OTF7, POUF3 ENSG00000184486 POU class 3 homeobox 2 6 98834592-98839470 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047081, HPA056261 Approved Supported Nucleus Tissue enriched Tissue enriched 70 cerebral cortex: 20.4 testis: 0.2 Cell line enhanced AF22: 123.9;U-251 MG: 32.8;WM-115: 33.3 +PTP4A3 PRL-3, PRL-R, PRL3 ENSG00000184489 Protein tyrosine phosphatase type IVA, member 3 8 141391993-141432454 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003281 Uncertain Renal cancer:1.81e-5 (unfavourable) Expressed in all Group enriched 6 heart muscle: 69.6;skeletal muscle: 153.1 prostate: 19.1 Cell line enhanced HDLM-2: 232.0;Karpas-707: 52.7;RPMI-8226: 54.1;U-266/84: 59.5 +FOXD4L1 FOXD5 ENSG00000184492 Forkhead box D4-like 1 2 113498665-113501155 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA012836 Uncertain Approved Nucleus Not detected Not detected testis: 0.6 Cell line enhanced RH-30: 1.6 +TMEM255B FAM70B, MGC20579 ENSG00000184497 Transmembrane protein 255B 13 113759240-113816995 Predicted membrane proteins, Transporters Evidence at protein level HPA043334 Approved Approved Nucleoplasm Renal cancer:4.12e-5 (unfavourable) Expressed in all Mixed lung: 8.3 Cell line enhanced HMC-1: 25.9;HUVEC TERT2: 32.5;PC-3: 36.6;TIME: 30.0;U-87 MG: 39.8 +PROS1 PROS ENSG00000184500 Protein S (alpha) 3 93873033-93974066 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007724, HPA023974 Enhanced Urothelial cancer:4.42e-5 (unfavourable), Stomach cancer:8.35e-4 (unfavourable) Expressed in all Tissue enhanced liver: 177.6 heart muscle: 78.3 Cell line enhanced ASC diff: 98.8;SK-MEL-30: 127.4 +GAST GAS ENSG00000184502 Gastrin 17 41712326-41715969 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB000038 Supported Group enriched Tissue enriched 200 stomach: 11203.5 duodenum: 55.9 Group enriched 6 BEWO: 2.6;HaCaT: 4.7;hTCEpi: 2.3 +NUTM1 C15orf55, DKFZp434O192, FAM22H, NUT ENSG00000184507 NUT midline carcinoma family member 1 15 34343315-34357737 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040421 Enhanced Not detected Tissue enriched 78 testis: 22.5 duodenum,skin: 0.2 Not detected +HDDC3 MGC45386 ENSG00000184508 HD domain containing 3 15 90929964-90932569 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040895 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all adrenal gland: 16.2 Expressed in all +BEX5 NGFRAP1L1 ENSG00000184515 Brain expressed X-linked 5 X 102153708-102156057 Predicted intracellular proteins Evidence at protein level HPA059058 Enhanced Renal cancer:1.97e-4 (favourable), Lung cancer:3.09e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 96.0 epididymis: 34.8 Cell line enhanced HAP1: 14.7;Karpas-707: 39.3 +ZFP1 FLJ34243, ZNF475 ENSG00000184517 ZFP1 zinc finger protein 16 75148492-75172236 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044916, HPA062910 Uncertain Approved Nucleus Glioma:5.81e-5 (favourable), Stomach cancer:9.80e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 25.0 Expressed in all +CEND1 BM88, FLJ90066 ENSG00000184524 Cell cycle exit and neuronal differentiation 1 11 787104-790123 Predicted membrane proteins Evidence at protein level HPA042527 Enhanced Approved Mitochondria Glioma:6.10e-5 (unfavourable) Tissue enriched Tissue enriched 16 cerebral cortex: 113.9 adrenal gland: 7.0 Cell line enhanced Karpas-707: 21.5;SCLC-21H: 62.8;SH-SY5Y: 21.2;U-266/70: 15.9;U-87 MG: 27.1 +C6orf58 LEG1 ENSG00000184530 Chromosome 6 open reading frame 58 6 127519455-127591817 Predicted secreted proteins Evidence at protein level HPA036263, HPA041449 Enhanced Group enriched Group enriched 21 duodenum: 603.5;salivary gland: 163.4;stomach: 314.9 esophagus: 17.1 Cell line enhanced RPMI-8226: 1.8;WM-115: 1.8 +DHRS7C SDR32C2 ENSG00000184544 Dehydrogenase/reductase 7C 17 9771434-9791297 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Not detected Group enriched 16 heart muscle: 62.4;skeletal muscle: 122.7 esophagus: 5.9 Not detected +DUSP8 C11orf81, FLJ42958, HB5, HVH-5 ENSG00000184545 Dual specificity phosphatase 8 11 1554044-1571920 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020071 Approved Approved Cytosol Renal cancer:2.75e-6 (favourable) Expressed in all Tissue enhanced cerebral cortex: 5.1 smooth muscle: 2.3 Cell line enhanced MCF7: 1.9;SH-SY5Y: 2.2 +SOCS3 CIS3, Cish3, SOCS-3, SSI-3 ENSG00000184557 Suppressor of cytokine signaling 3 17 78356778-78360077 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB012220, HPA068569 Approved Approved Cytosol Renal cancer:9.34e-9 (unfavourable), Breast cancer:4.80e-4 (favourable) Expressed in all Tissue enhanced adipose tissue: 321.5 gallbladder: 297.9 Cell line enhanced HDLM-2: 142.9 +C17orf74 ENSG00000184560 Chromosome 17 open reading frame 74 17 7425615-7427568 Predicted membrane proteins Evidence at transcript level HPA023649 Uncertain Not detected Tissue enriched 308 testis: 30.8 all non-specific tissues: 0.0 Not detected +SLITRK6 FLJ22774 ENSG00000184564 SLIT and NTRK like family member 6 13 85792790-85799488 Disease related genes, Predicted membrane proteins Evidence at protein level HPA014491, HPA014513 Uncertain Supported Plasma membrane Head and neck cancer:8.52e-4 (unfavourable) Tissue enhanced Tissue enhanced urinary bladder: 19.6 prostate: 12.1 Group enriched 12 hTCEpi: 19.1;RT4: 76.0;WM-115: 21.9 +PIWIL3 HIWI3 ENSG00000184571 Piwi like RNA-mediated gene silencing 3 22 24719034-24774720 Predicted intracellular proteins Evidence at protein level HPA061955 Uncertain Not detected Tissue enriched 13 testis: 1.7 skin: 0.1 Not detected +LPAR5 GPR92, GPR93, KPG_010, LPA5 ENSG00000184574 Lysophosphatidic acid receptor 5 12 6618835-6636447 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013170 Approved Thyroid cancer:6.56e-5 (favourable) Mixed Mixed tonsil: 10.6 Cell line enhanced HEL: 16.4;HMC-1: 22.4;K-562: 12.4 +XPOT XPO3 ENSG00000184575 Exportin for tRNA 12 64404350-64451127 Predicted intracellular proteins, Transporters Evidence at protein level HPA048067, HPA057602 Enhanced Nucleoplasm
Cytosol Renal cancer:2.41e-12 (unfavourable), Liver cancer:1.81e-7 (unfavourable), Urothelial cancer:5.79e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 83.0 Expressed in all +TMEM173 ERIS, FLJ38577, MITA, MPYS, NET23, STING ENSG00000184584 Transmembrane protein 173 5 139475534-139482935 Disease related genes, Predicted membrane proteins Evidence at protein level HPA038116, HPA038534 Enhanced Renal cancer:3.59e-8 (unfavourable) Expressed in all Expressed in all fallopian tube: 70.7 Cell line enhanced EFO-21: 150.4;HDLM-2: 331.0 +PDE4B DPDE4 ENSG00000184588 Phosphodiesterase 4B 1 65792514-66374579 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003005 Uncertain Approved Golgi apparatus
Cytosol Renal cancer:5.04e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 67.0 Cell line enhanced AN3-CA: 57.3;HUVEC TERT2: 77.6;NTERA-2: 56.0 +FAM19A3 TAFA-3, TAFA3 ENSG00000184599 Family with sequence similarity 19 member A3, C-C motif chemokine like 1 112720419-112727235 Predicted secreted proteins Evidence at transcript level HPA055927 Approved Glioma:8.24e-4 (unfavourable) Mixed Group enriched 15 adrenal gland: 19.9;testis: 8.7 epididymis: 0.9 Cell line enhanced BJ hTERT+: 3.7;HEL: 1.6;U-87 MG: 1.7 +C14orf180 C14orf77, NRAC ENSG00000184601 Chromosome 14 open reading frame 180 14 104579684-104590515 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Tissue enhanced Group enriched 19 adipose tissue: 34.5;heart muscle: 28.5 adrenal gland: 1.6 Cell line enriched 14 ASC diff: 2.0 +SNN ENSG00000184602 Stannin 16 11668414-11679159 Predicted membrane proteins Evidence at protein level HPA011055 Approved Approved Cytosol Liver cancer:1.85e-6 (unfavourable), Renal cancer:1.83e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 150.6 Expressed in all +KCNH7 erg3, HERG3, Kv11.3 ENSG00000184611 Potassium voltage-gated channel subfamily H member 7 2 162371407-162838730 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA018039 Uncertain Not detected Tissue enriched 7 cerebral cortex: 4.7 stomach,testis: 0.6 Group enriched 12 SCLC-21H: 7.7;SK-BR-3: 4.4 +NELL2 NRP2 ENSG00000184613 Neural EGFL like 2 12 44508275-44921848 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035714, HPA035715 Uncertain Approved Vesicles Pancreatic cancer:5.56e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 204.1;fallopian tube: 96.7 prostate: 46.5 Cell line enhanced AF22: 102.5;NTERA-2: 41.0;SCLC-21H: 88.2 +KRBA2 ENSG00000184619 KRAB-A domain containing 2 17 8368637-8376711 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA022849 Approved Approved Nucleoplasm Not detected Mixed parathyroid gland: 7.3 Mixed +MED12 CAGH45, FGS1, HOPA, KIAA0192, OKS, OPA1, TNRC11, TRAP230 ENSG00000184634 Mediator complex subunit 12 X 71118556-71142454 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003184, HPA003185 Enhanced Approved Nucleoplasm Expressed in all Expressed in all ovary: 26.8 Expressed in all +ZNF93 FLJ12488, HPF34, TF34, ZNF505 ENSG00000184635 Zinc finger protein 93 19 19900913-19935575 Predicted intracellular proteins, Transcription factors Evidence at protein level Ovarian cancer:9.31e-6 (favourable) Mixed Mixed thyroid gland: 13.9 Cell line enhanced NTERA-2: 41.8 +SEPT9 AF17q25, KIAA0991, MSF, MSF1, PNUTL4, SeptD1 ENSG00000184640 Septin 9 17 77280569-77500596 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042564, HPA050627 Approved Enhanced Actin filaments Liver cancer:1.61e-5 (unfavourable) Expressed in all Expressed in all lymph node: 268.9 Expressed in all +PRSS55 CT153, T-SP1, UNQ9391 ENSG00000184647 Protease, serine 55 8 10525546-10554166 Enzymes, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 92 testis: 26.1 epididymis: 0.2 Not detected +ODF4 CT136, OPPO1 ENSG00000184650 Outer dense fiber of sperm tails 4 17 8339864-8346048 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 172 testis: 17.1 all non-specific tissues: 0.0 Not detected +FOXD4L4 bA460E7.2, FOXD4L2 ENSG00000184659 Forkhead box D4-like 4 9 65736555-65738784 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA012836 Uncertain Approved Nucleus Not detected Not detected cerebral cortex: 0.1 Not detected +CDCA2 PPP1R81, Repo-Man ENSG00000184661 Cell division cycle associated 2 8 25458997-25507920 Predicted intracellular proteins Evidence at protein level HPA026293, HPA030049 Approved Enhanced Nucleoplasm Renal cancer:2.30e-14 (unfavourable), Colorectal cancer:9.62e-4 (favourable) Mixed Tissue enriched 6 testis: 31.4 lymph node: 5.4 Mixed +RALYL HNRPCL3 ENSG00000184672 RALY RNA binding protein-like 8 84182787-84921844 Predicted intracellular proteins Evidence at protein level HPA055868, HPA059112 Enhanced Approved Nucleoplasm Tissue enhanced Tissue enhanced adrenal gland: 26.1;cerebral cortex: 49.2;kidney: 19.7 gallbladder: 8.1 Cell line enhanced AF22: 4.0 +AMER1 FAM123B, FLJ39827, RP11-403E24.2, WTX ENSG00000184675 APC membrane recruitment protein 1 X 64185117-64205744 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065214, HPA065265 Approved Supported Nuclear bodies
Vesicles
Plasma membrane Expressed in all Mixed ovary: 7.7 Mixed +ZBTB40 KIAA0478, ZNF923 ENSG00000184677 Zinc finger and BTB domain containing 40 1 22451851-22531157 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042386 Approved Nucleus Liver cancer:7.78e-8 (unfavourable), Pancreatic cancer:4.12e-5 (favourable), Head and neck cancer:2.01e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 20.8 Mixed +HIST2H2BE H2B, H2B.1, H2B/q, H2BFQ ENSG00000184678 Histone cluster 2 H2B family member e 1 149884459-149886652 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Colorectal cancer:2.90e-4 (unfavourable) Expressed in all Expressed in all prostate: 113.5 Cell line enhanced Karpas-707: 40.8;U-266/70: 71.4 +CLDN6 ENSG00000184697 Claudin 6 16 3014712-3020071 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Endometrial cancer:2.42e-6 (unfavourable), Urothelial cancer:1.78e-4 (unfavourable) Group enriched Tissue enhanced placenta: 1.0;testis: 1.7 cerebral cortex,lung: 0.3 Group enriched 8 BEWO: 460.1;CACO-2: 110.7;NTERA-2: 441.6 +OR51M1 ENSG00000184698 Olfactory receptor family 51 subfamily M member 1 11 5389399-5390379 G-protein coupled receptors, Predicted membrane proteins No evidence HPA056773 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +SEPT5 H5, HCDCREL-1, PNUTL1 ENSG00000184702 Septin 5 22 19714464-19724772 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB016120, HPA029095, HPA063885 Enhanced Approved Nucleoplasm
Actin filaments
Cytosol Renal cancer:6.87e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 386.8 Cell line enhanced K-562: 211.0 +EIF4ENIF1 2610509L04Rik, 4E-T, Clast4, FLJ21601 ENSG00000184708 Eukaryotic translation initiation factor 4E nuclear import factor 1 22 31436977-31496108 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001619, HPA002078 Enhanced Enhanced Vesicles Renal cancer:1.57e-4 (favourable) Expressed in all Expressed in all testis: 65.0 Expressed in all +LRRC26 bA350O14.10 ENSG00000184709 Leucine rich repeat containing 26 9 137168758-137170051 Predicted membrane proteins Evidence at protein level HPA056312 Approved Supported Nucleoli fibrillar center
Plasma membrane Endometrial cancer:4.82e-6 (favourable), Stomach cancer:3.48e-4 (favourable) Tissue enriched Group enriched 7 colon: 10.2;prostate: 35.5;salivary gland: 26.5 small intestine: 3.5 Group enriched 10 REH: 18.9;RPMI-8226: 87.4 +SERINC4 FLJ40363 ENSG00000184716 Serine incorporator 4 15 43794162-43800221 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 10 testis: 2.3 endometrium: 0.2 Not detected +RNLS C10orf59, FLJ11218, renalase ENSG00000184719 Renalase, FAD dependent amine oxidase 10 88273864-88584530 Enzymes, Predicted secreted proteins Evidence at protein level Expressed in all Expressed in all kidney: 26.5 Mixed +KRTAP6-1 C21orf103, KAP6.1 ENSG00000184724 Keratin associated protein 6-1 21 30613431-30613930 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +APOBR APOB100R, APOB48R ENSG00000184730 Apolipoprotein B receptor 16 28494649-28498970 Predicted intracellular proteins Evidence at protein level HPA041667, HPA042093 Enhanced Endometrial cancer:3.26e-4 (favourable) Expressed in all Tissue enhanced spleen: 30.4 appendix: 27.1 Cell line enhanced HEL: 37.0;HMC-1: 109.0;NB-4: 22.6;U-937: 24.2 +FAM110C ENSG00000184731 Family with sequence similarity 110 member C 2 38814-46870 Predicted intracellular proteins Evidence at protein level HPA036144, HPA036145 Uncertain Glioma:6.77e-4 (unfavourable) Mixed Mixed seminal vesicle: 29.0 Cell line enhanced HaCaT: 11.8;RPTEC TERT1: 13.6;RT4: 20.1 +DDX53 CAGE, CT26 ENSG00000184735 DEAD-box helicase 53 X 22999961-23003589 Enzymes, Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 100 testis: 10.0 all non-specific tissues: 0.0 Cell line enhanced K-562: 4.1;RPMI-8226: 1.6;U-2197: 1.3;U-266/84: 7.3 +ATL3 DKFZP564J0863 ENSG00000184743 Atlastin GTPase 3 11 63624087-63671921 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA065702, HPA076616 Enhanced Endoplasmic reticulum Pancreatic cancer:1.04e-4 (unfavourable) Expressed in all Expressed in all testis: 65.6 Mixed +NDUFA12 B17.2, DAP13 ENSG00000184752 NADH:ubiquinone oxidoreductase subunit A12 12 94897055-95003770 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039903 Supported Supported Mitochondria Expressed in all Expressed in all heart muscle: 189.2 Expressed in all +AC013269.5 ENSG00000184761 2 130539095-130549883 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +SMIM10 CXorf69 ENSG00000184785 Small integral membrane protein 10 X 134990938-134992473 Predicted membrane proteins Evidence at transcript level Renal cancer:3.69e-6 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 63.4;testis: 50.6 fallopian tube: 17.7 Mixed +TCTE3 TCTEX1D3 ENSG00000184786 T-complex-associated-testis-expressed 3 6 169740114-169751587 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 173 testis: 17.2 all non-specific tissues: 0.0 Not detected +UBE2G2 UBC7 ENSG00000184787 Ubiquitin conjugating enzyme E2 G2 21 44768580-44802019 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003332 Approved Renal cancer:7.02e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 26.5 Expressed in all +SATL1 ENSG00000184788 Spermidine/spermine N1-acetyl transferase-like 1 X 85092287-85109048 Predicted intracellular proteins Evidence at transcript level HPA060369 Uncertain Not detected Tissue enhanced testis: 1.3 cerebral cortex: 0.4 Not detected +OSBP2 KIAA1664, ORP-4, ORP4, OSBPL1 ENSG00000184792 Oxysterol binding protein 2 22 30693782-30907824 Predicted intracellular proteins Evidence at protein level HPA021514 Uncertain Approved Cytosol Renal cancer:3.79e-6 (favourable) Expressed in all Tissue enhanced testis: 34.5 bone marrow: 31.8 Cell line enhanced HeLa: 98.3;SiHa: 41.6 +TUSC5 IFITMD3, LOST1 ENSG00000184811 Tumor suppressor candidate 5 17 1279663-1300987 Predicted membrane proteins Evidence at protein level HPA050825 Approved Tissue enhanced Tissue enriched 18 adipose tissue: 110.0 breast: 6.1 Cell line enriched 207 ASC diff: 20.6 +PRR23B FLJ46116 ENSG00000184814 Proline rich 23B 3 139019031-139020926 Predicted intracellular proteins Evidence at transcript level HPA047473 Uncertain Not detected Tissue enriched 16 testis: 1.5 all non-specific tissues: 0.0 Not detected +ZBTB7C ZBTB36, ZNF857C ENSG00000184828 Zinc finger and BTB domain containing 7C 18 48026673-48410752 Predicted intracellular proteins, Transcription factors Evidence at transcript level Colorectal cancer:1.59e-4 (favourable) Mixed Mixed esophagus: 31.7 Cell line enhanced RPMI-8226: 6.7;RT4: 34.0;SCLC-21H: 6.5;SH-SY5Y: 7.3 +APOO FAM121B, MGC4825, Mic23, MIC26, My025 ENSG00000184831 Apolipoprotein O X 23833353-23907934 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003187 Supported Approved Mitochondria
Cytosol Renal cancer:2.56e-6 (favourable), Cervical cancer:3.77e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 50.8 Expressed in all +PRR16 DSC54 ENSG00000184838 Proline rich 16 5 120464278-120687332 Predicted intracellular proteins Evidence at protein level HPA049254 Approved Approved Nucleus
Midbody
Cytosol Tissue enriched Mixed cervix, uterine: 21.7 Cell line enhanced BJ hTERT+: 67.6;fHDF/TERT166: 78.9;LHCN-M2: 80.9;U-138 MG: 115.3 +TMED9 HSGP25L2G, p24a2, p24alpha2 ENSG00000184840 Transmembrane p24 trafficking protein 9 5 177592158-177596124 Predicted membrane proteins Evidence at protein level HPA014650 Approved Renal cancer:5.88e-5 (unfavourable) Expressed in all Expressed in all placenta: 212.7 Expressed in all +DRD1 ENSG00000184845 Dopamine receptor D1 5 175440039-175444208 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013393 Supported Mixed Tissue enhanced cerebral cortex: 8.0 prostate: 1.7 Group enriched 10 RT4: 20.9;U-2 OS: 5.4 +TMEM186 C16orf51, DKFZP564K2062 ENSG00000184857 Transmembrane protein 186 16 8780384-8797648 Predicted membrane proteins Evidence at protein level HPA018226, HPA063559 Uncertain Approved Cell Junctions Renal cancer:1.93e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 23.0 Expressed in all +SDR42E1 HSPC105 ENSG00000184860 Short chain dehydrogenase/reductase family 42E, member 1 16 81988855-82011488 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA014388 Uncertain Mixed Mixed skin: 10.7 Cell line enhanced hTCEpi: 8.4;RT4: 15.4;SCLC-21H: 9.5 +RBM33 DKFZp434D1319, DKFZp686F102, MGC20460, PRR8 ENSG00000184863 RNA binding motif protein 33 7 155644451-155781485 Predicted intracellular proteins Evidence at protein level HPA019232, HPA021497, HPA021768 Approved Approved Nucleoplasm Head and neck cancer:9.63e-5 (favourable), Renal cancer:1.05e-4 (unfavourable), Urothelial cancer:4.29e-4 (favourable) Expressed in all Expressed in all bone marrow: 40.8 Expressed in all +ARMCX2 ALEX2, GASP9, KIAA0512 ENSG00000184867 Armadillo repeat containing, X-linked 2 X 101655281-101659891 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA005761 Enhanced Approved Nucleus
Mitochondria Pancreatic cancer:3.45e-5 (favourable), Stomach cancer:2.69e-4 (unfavourable) Expressed in all Tissue enhanced epididymis: 202.3 thyroid gland: 107.5 Cell line enhanced LHCN-M2: 146.0;NTERA-2: 125.3 +BTBD6 BDPL ENSG00000184887 BTB domain containing 6 14 105248490-105251093 Predicted intracellular proteins Evidence at protein level HPA031355 Approved Approved Nucleoplasm Renal cancer:6.51e-5 (favourable), Breast cancer:1.11e-4 (favourable), Pancreatic cancer:2.25e-4 (favourable) Expressed in all Expressed in all testis: 73.4 Mixed +SRY TDF ENSG00000184895 Sex determining region Y Y 2786855-2787699 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enhanced Tissue enhanced skin: 1.0;testis: 2.8 esophagus: 0.7 Cell line enhanced RT4: 1.7 +H1FX H1X, MGC15959, MGC8350 ENSG00000184897 H1 histone family member X 3 129314771-129316277 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012235, HPA040099 Supported Enhanced Nucleus
Nucleoli Expressed in all Tissue enriched 7 bone marrow: 670.4 spleen: 95.9 Expressed in all +RBM43 C2orf38, FLJ45645 ENSG00000184898 RNA binding motif protein 43 2 151247940-151261879 Predicted intracellular proteins Evidence at protein level HPA038204 Uncertain Approved Nucleus
Nucleoli Expressed in all Mixed thyroid gland: 20.6 Mixed +SUMO3 SMT3A, SMT3H1 ENSG00000184900 Small ubiquitin-like modifier 3 21 44805617-44818779 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012180, HPA042123, HPA048064 Supported Enhanced Nucleoplasm
Nuclear bodies Endometrial cancer:7.88e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 80.8 Expressed in all +IMMP2L IMMP2L-IT1, IMP2 ENSG00000184903 Inner mitochondrial membrane peptidase subunit 2 7 110663051-111562517 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026711 Approved Approved Mitochondria Head and neck cancer:1.89e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 39.4 Expressed in all +TCEAL2 my048, MY0876G05, WEX1 ENSG00000184905 Transcription elongation factor A like 2 X 102125688-102127711 Predicted intracellular proteins Evidence at protein level HPA076317 Approved Nuclear speckles
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 191.7 ovary: 77.7 Cell line enhanced HAP1: 6.0;SCLC-21H: 7.3;U-2 OS: 11.7 +CLCNKB hClC-Kb ENSG00000184908 Chloride voltage-gated channel Kb 1 16043736-16057308 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA057717 Approved Renal cancer:1.27e-7 (favourable) Tissue enriched Tissue enhanced kidney: 107.9 salivary gland: 22.0 Cell line enhanced EFO-21: 1.5 +DMRTC1B ENSG00000184911 DMRT like family C1B X 72777009-72848802 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA046874, HPA046992 Uncertain Not detected Tissue enhanced cerebral cortex: 16.6 ovary: 10.3 Not detected +JAG2 ENSG00000184916 Jagged 2 14 105140981-105168824 Predicted membrane proteins Evidence at protein level CAB025481, HPA030636, HPA050567 Approved Supported Vesicles
Cytosol Expressed in all Tissue enhanced skin: 22.5 adipose tissue: 6.5 Cell line enhanced HaCaT: 54.2;SCLC-21H: 36.3 +FMNL1 C17orf1, C17orf1B, FMNL ENSG00000184922 Formin like 1 17 45221444-45247320 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008129, HPA028288 Enhanced Approved Cytosol Renal cancer:4.23e-8 (unfavourable) Expressed in all Expressed in all bone marrow: 175.0 Cell line enhanced Karpas-707: 137.1;MOLT-4: 110.5;U-266/70: 120.6 +NUTM2A FAM22A ENSG00000184923 NUT family member 2A 10 87225448-87236908 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Not detected Mixed skin: 1.9 Cell line enhanced HMC-1: 8.3 +PTRHD1 C2orf79, LOC391356 ENSG00000184924 Peptidyl-tRNA hydrolase domain containing 1 2 24789734-24793382 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019951 Approved Approved Nucleoplasm Renal cancer:2.31e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 14.0 Expressed in all +LCN12 MGC48935 ENSG00000184925 Lipocalin 12 9 136949551-136955497 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enriched 31 epididymis: 45.4 thyroid gland: 1.4 Not detected +OR6A2 OR11-55, OR6A1, OR6A2P ENSG00000184933 Olfactory receptor family 6 subfamily A member 2 11 6794627-6795783 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +WT1 AWT1, GUD, NPHS4, WAGR, WIT-2 ENSG00000184937 Wilms tumor 1 11 32387775-32435630 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000327, HPA035717, HPA053848 Enhanced Supported Nucleoplasm Tissue enriched Tissue enhanced endometrium: 112.9;fallopian tube: 126.5;smooth muscle: 80.2 testis: 55.1 Cell line enhanced HEL: 23.8;HMC-1: 28.7;K-562: 21.7;NB-4: 40.6;THP-1: 20.5 +ZFP90 KIAA1954, NK10, ZNF756 ENSG00000184939 ZFP90 zinc finger protein 16 68530090-68576072 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029017 Uncertain Supported Vesicles
Plasma membrane
Centrosome Renal cancer:1.78e-4 (favourable) Expressed in all Mixed parathyroid gland: 31.7 Mixed +AQP12A AQP12 ENSG00000184945 Aquaporin 12A 2 240691845-240698483 Predicted membrane proteins, Transporters Evidence at protein level HPA042216 Supported Not detected Tissue enriched 68 pancreas: 27.8 small intestine: 0.4 Not detected +FAM227A ENSG00000184949 Family with sequence similarity 227 member A 22 38578120-38656629 Predicted intracellular proteins Evidence at protein level HPA003077 Uncertain Uncertain Nucleoplasm Mixed Tissue enhanced fallopian tube: 3.7 testis: 3.5 Group enriched 6 HDLM-2: 11.1;Karpas-707: 14.1 +OR6C70 ENSG00000184954 Olfactory receptor family 6 subfamily C member 70 12 55469200-55470138 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 6 Karpas-707: 1.6 +MUC6 ENSG00000184956 Mucin 6, oligomeric mucus/gel-forming 11 1012821-1036706 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002165 Enhanced Tissue enhanced Group enriched 24 duodenum: 15.4;seminal vesicle: 40.2;stomach: 24.0 epididymis: 1.1 Not detected +NOC4L MGC3162, NET49, UTP19 ENSG00000184967 Nucleolar complex associated 4 homolog 12 132144448-132152473 Predicted intracellular proteins Evidence at protein level HPA053424 Supported Nucleus
Nucleoli Expressed in all Expressed in all testis: 24.7 Expressed in all +USP18 ENSG00000184979 Ubiquitin specific peptidase 18 22 18149899-18177397 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044768 Uncertain Approved Cytosol Expressed in all Mixed testis: 15.4 Cell line enhanced BJ hTERT+ SV40 Large T+: 144.8;BJ hTERT+ SV40 Large T+ RasG12V: 163.7 +NDUFA6 B14, CI-B14, LYRM6, NADHB14 ENSG00000184983 NADH:ubiquinone oxidoreductase subunit A6 22 42085525-42090955 Predicted intracellular proteins Evidence at protein level Renal cancer:1.05e-6 (favourable), Cervical cancer:3.87e-4 (favourable), Endometrial cancer:4.96e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 39.6 Mixed +CHRM5 ENSG00000184984 Cholinergic receptor muscarinic 5 15 33968720-34067457 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA013172 Uncertain Not detected Tissue enhanced cerebral cortex: 3.1;testis: 3.4 placenta: 2.3 Group enriched 7 BEWO: 4.5;HMC-1: 14.3 +SORCS2 KIAA1329 ENSG00000184985 Sortilin related VPS10 domain containing receptor 2 4 7192538-7742836 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA061916 Approved Nucleus
Cytosol Renal cancer:3.09e-4 (unfavourable), Ovarian cancer:3.55e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 19.3 cervix, uterine: 10.4 Cell line enhanced HaCaT: 17.3;HMC-1: 12.7;SiHa: 15.0 +TMEM121 hole, MGC4659 ENSG00000184986 Transmembrane protein 121 14 105526603-105530202 Predicted membrane proteins Evidence at transcript level HPA049857 Uncertain Approved Cytosol Thyroid cancer:5.87e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 4.8 spleen: 2.4 Cell line enhanced EFO-21: 7.7;MCF7: 6.1;PC-3: 9.5;REH: 6.1;SCLC-21H: 6.2 +TMEM106A MGC20235 ENSG00000184988 Transmembrane protein 106A 17 43211835-43220041 Predicted membrane proteins Evidence at transcript level Colorectal cancer:9.61e-5 (unfavourable) Expressed in all Mixed kidney: 23.2 Mixed +SIVA1 CD27BP, SIVA, Siva-1, Siva-2 ENSG00000184990 SIVA1 apoptosis inducing factor 14 104753100-104768494 Predicted intracellular proteins Evidence at protein level HPA065398, HPA066693 Supported Nucleoplasm Cervical cancer:5.95e-4 (favourable) Expressed in all Expressed in all bone marrow: 62.0 Expressed in all +BRI3BP BNAS1, HCCR-2, HCCRBP-3, KG19 ENSG00000184992 BRI3 binding protein 12 124993700-125031231 Predicted membrane proteins, Transporters Evidence at protein level HPA014957 Approved Approved Nucleoplasm
Mitochondria Liver cancer:6.87e-4 (unfavourable) Expressed in all Mixed duodenum: 20.5 Expressed in all +IFNE IFNE1 ENSG00000184995 Interferon epsilon 9 21480839-21482313 Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced epididymis: 1.1 urinary bladder: 0.8 Cell line enhanced BJ: 2.7;HeLa: 5.5 +SLC22A10 hOAT5, OAT5 ENSG00000184999 Solute carrier family 22 member 10 11 63137867-63369718 Predicted membrane proteins, Transporters Evidence at transcript level Tissue enriched Tissue enriched 106 liver: 36.2 epididymis: 0.3 Not detected +DGAT1 ARGP1, DGAT ENSG00000185000 Diacylglycerol O-acyltransferase 1 8 144314584-144326910 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB032853 Enhanced Approved Nucleoli
Endoplasmic reticulum Expressed in all Tissue enhanced duodenum: 71.3;small intestine: 75.1 adipose tissue: 20.0 Cell line enhanced PC-3: 35.6 +RFX6 dJ955L16.1, MGC33442, RFXDC1 ENSG00000185002 Regulatory factor X6 6 116877212-116932163 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA037696, HPA037697 Approved Supported Nucleus
Nucleoli Pancreatic cancer:3.59e-4 (favourable) Tissue enhanced Tissue enhanced adrenal gland: 5.9;stomach: 7.2 duodenum: 2.3 Cell line enhanced HEK 293: 1.2 +ROBO2 KIAA1568 ENSG00000185008 Roundabout guidance receptor 2 3 75906695-77649964 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013371 Approved Approved Nucleus
Microtubule organizing center Tissue enhanced Tissue enhanced cerebral cortex: 33.8 lung: 15.1 Cell line enhanced BJ hTERT+: 24.2;HEL: 75.2 +AP3M1 ENSG00000185009 Adaptor related protein complex 3 mu 1 subunit 10 74120255-74151063 Predicted intracellular proteins Evidence at protein level HPA045591, HPA048380 Uncertain Expressed in all Expressed in all placenta: 46.0 Expressed in all +F8 DXS1253E, F8C, FVIII, HEMA ENSG00000185010 Coagulation factor VIII X 154835788-155026940 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB018777 Enhanced Expressed in all Expressed in all lung: 23.4 Mixed +NT5C1B AIRP, CN-IB ENSG00000185013 5'-nucleotidase, cytosolic IB 2 18562872-18589572 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at transcript level HPA056683 Uncertain Not detected Tissue enriched 43 testis: 57.5 skin: 1.3 Mixed +CA13 CAXIII, FLJ37995, MGC59868 ENSG00000185015 Carbonic anhydrase 13 8 85220587-85284073 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024689, CAB025567 Enhanced Uncertain Nucleus
Nucleoli
Vesicles Renal cancer:9.40e-4 (favourable) Expressed in all Mixed small intestine: 16.5 Cell line enhanced HEL: 14.2 +UBOX5 KIAA0860, RNF37, Ubce7ip5, UIP5 ENSG00000185019 U-box domain containing 5 20 3107573-3160196 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028871 Approved Approved Nucleoplasm Pancreatic cancer:1.80e-5 (favourable), Head and neck cancer:4.52e-5 (favourable) Expressed in all Expressed in all fallopian tube: 7.1 Expressed in all +MAFF hMafF ENSG00000185022 MAF bZIP transcription factor F 22 38200767-38216511 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB025341, HPA055371 Approved Approved Nucleus
Mitochondria Breast cancer:4.32e-4 (favourable) Expressed in all Mixed gallbladder: 66.3 Cell line enhanced hTEC/SVTERT24-B: 79.2;SK-MEL-30: 75.4 +BRF1 BRF, GTF3B, hBRF, TAF3B2, TAF3C, TFIIIB90 ENSG00000185024 BRF1, RNA polymerase III transcription initiation factor subunit 14 105209286-105315589 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051918 Approved Nucleoplasm
Nuclear bodies Pancreatic cancer:7.25e-6 (favourable), Renal cancer:1.13e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 21.7 Expressed in all +LRRC14B ENSG00000185028 Leucine rich repeat containing 14B 5 191511-195353 Predicted intracellular proteins Evidence at protein level HPA038046, HPA038047 Uncertain Tissue enhanced Group enriched 26 heart muscle: 13.6;skeletal muscle: 30.1 prostate: 0.8 Cell line enhanced REH: 6.8;U-266/70: 7.1;U-266/84: 28.6 +SEMA4B KIAA1745, MGC131831, SEMAC, SemC ENSG00000185033 Semaphorin 4B 15 90160604-90229679 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013372 Approved Renal cancer:3.33e-8 (unfavourable), Lung cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all esophagus: 49.3 Expressed in all +MROH2A HEATR7B1 ENSG00000185038 Maestro heat like repeat family member 2A 2 233775679-233833423 Predicted intracellular proteins Evidence at transcript level HPA052107 Uncertain Uncertain Cytosol Tissue enhanced Group enriched 8 testis: 3.2;thyroid gland: 2.7 liver,stomach: 0.3 Cell line enriched 8 RT4: 4.8 +SPDYE16 ENSG00000185040 Speedy/RINGO cell cycle regulator family member E16 7 76531319-76541459 Predicted intracellular proteins Evidence at protein level HPA051750 Supported Not detected Not detected testis: 0.6 Cell line enhanced HeLa: 1.9 +CIB1 CIB, KIP, SIP2-28 ENSG00000185043 Calcium and integrin binding 1 15 90229975-90234047 Predicted intracellular proteins Evidence at protein level CAB012991, HPA042413, HPA048825 Approved Supported Nucleoplasm
Plasma membrane Endometrial cancer:2.26e-5 (favourable) Expressed in all Expressed in all fallopian tube: 207.5 Expressed in all +ANKS1B AIDA-1, ANKS2, cajalin-2, EB-1 ENSG00000185046 Ankyrin repeat and sterile alpha motif domain containing 1B 12 98726457-99984654 Predicted intracellular proteins Evidence at protein level HPA044628 Approved Vesicles
Plasma membrane
Cytosol Tissue enhanced Tissue enriched 8 cerebral cortex: 111.9 testis: 14.0 Cell line enhanced AF22: 10.0;SCLC-21H: 13.0 +NELFA NELF-A, WHSC2 ENSG00000185049 Negative elongation factor complex member A 4 1982714-2041903 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009960, HPA039858, HPA043931 Enhanced Enhanced Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:4.35e-4 (unfavourable) Expressed in all Expressed in all testis: 31.7 Expressed in all +SLC24A3 ENSG00000185052 Solute carrier family 24 member 3 20 19212646-19722937 Predicted membrane proteins, Transporters Evidence at protein level HPA043400, HPA045497 Uncertain Thyroid cancer:6.08e-4 (unfavourable) Mixed Mixed endometrium: 47.7 Cell line enhanced BJ hTERT+: 10.7;HEL: 16.2;HMC-1: 68.3;T-47d: 15.9 +SGCZ ZSG1 ENSG00000185053 Sarcoglycan zeta 8 14089864-15238339 Predicted membrane proteins Evidence at transcript level HPA017585 Uncertain Not detected Tissue enhanced cerebral cortex: 1.3;ovary: 3.4 breast: 0.7 Not detected +EFCAB10 ENSG00000185055 EF-hand calcium binding domain 10 7 105565120-105600875 Predicted intracellular proteins Evidence at transcript level HPA019751 Uncertain Mixed Group enriched 10 fallopian tube: 44.0;testis: 39.9 lung: 4.3 Mixed +C5orf47 LOC133491 ENSG00000185056 Chromosome 5 open reading frame 47 5 173973779-174006140 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 250 testis: 39.4 cerebral cortex,parathyroid gland: 0.1 Not detected +KRT76 HUMCYT2A, KRT2B, KRT2P ENSG00000185069 Keratin 76 12 52768155-52777345 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019656, HPA019696 Approved Tissue enriched Tissue enriched 22 tonsil: 2.1 all non-specific tissues: 0.0 Not detected +FLRT2 ENSG00000185070 Fibronectin leucine rich transmembrane protein 2 14 85530144-85654426 Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced ovary: 36.4 cervix, uterine: 16.7 Cell line enhanced hTERT-HME1: 46.2;TIME: 45.0;U-138 MG: 57.9;U-2197: 39.9 +INTS5 INT5, KIAA1698 ENSG00000185085 Integrator complex subunit 5 11 62646848-62653302 Predicted intracellular proteins Evidence at protein level HPA056915 Uncertain Supported Nucleus Renal cancer:8.44e-5 (favourable) Expressed in all Expressed in all fallopian tube: 21.0 Expressed in all +RPS27L ENSG00000185088 Ribosomal protein S27 like 15 63125872-63158021 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA066851 Supported Nucleoli
Endoplasmic reticulum
Cytosol Endometrial cancer:9.08e-6 (favourable) Expressed in all Expressed in all adrenal gland: 222.3 Expressed in all +MANEAL FLJ31434 ENSG00000185090 Mannosidase endo-alpha like 1 37793802-37801137 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA063423 Approved Golgi apparatus Liver cancer:3.32e-4 (unfavourable), Head and neck cancer:5.28e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 27.2 adrenal gland: 9.5 Cell line enhanced SCLC-21H: 167.3 +ADSSL1 FLJ38602 ENSG00000185100 Adenylosuccinate synthase like 1 14 104724186-104747325 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Renal cancer:4.99e-4 (unfavourable) Mixed Tissue enriched 7 skeletal muscle: 428.0 heart muscle: 63.0 Cell line enhanced EFO-21: 13.7;MCF7: 10.4;SiHa: 23.7 +ANO9 PIG5, TMEM16J, TP53I5 ENSG00000185101 Anoctamin 9 11 417933-442011 Predicted membrane proteins, Transporters Evidence at protein level HPA039948, HPA040112 Approved Uncertain Golgi apparatus Urothelial cancer:8.81e-4 (favourable) Tissue enhanced Tissue enhanced duodenum: 31.6;small intestine: 30.9 skin: 21.6 Cell line enhanced BEWO: 8.6;CAPAN-2: 24.1;HaCaT: 14.1;RPMI-8226: 13.6 +FAF1 CGI-03, hFAF1, HFAF1s, UBXD12, UBXN3A ENSG00000185104 Fas associated factor 1 1 50437028-50960263 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018253, CAB072814 Approved Enhanced Nucleus Liver cancer:1.87e-5 (unfavourable) Expressed in all Expressed in all testis: 59.5 Mixed +MYADML2 LOC255275 ENSG00000185105 Myeloid associated differentiation marker like 2 17 81939645-81947233 Predicted membrane proteins Evidence at transcript level HPA041856, HPA048476 Uncertain Tissue enhanced Tissue enriched 17 skeletal muscle: 28.8 heart muscle: 1.6 Cell line enriched 8 SCLC-21H: 3.6 +FAM43A FLJ90022 ENSG00000185112 Family with sequence similarity 43 member A 3 194686544-194689037 Predicted intracellular proteins Evidence at protein level HPA048345 Uncertain Approved Vesicles Urothelial cancer:9.96e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 34.0 placenta: 18.2 Cell line enhanced HUVEC TERT2: 113.2;NB-4: 52.7;PC-3: 59.3;TIME: 55.9 +NSMCE3 HCA4, MAGEG1, MAGEL3, NDNL2, NSE3 ENSG00000185115 NSE3 homolog, SMC5-SMC6 complex component 15 29264992-29269829 Disease related genes, Predicted intracellular proteins Evidence at protein level Head and neck cancer:1.94e-4 (unfavourable) Expressed in all Not detected cerebral cortex: 0.8 Not detected +HSF1 HSTF1 ENSG00000185122 Heat shock transcription factor 1 8 144291591-144314722 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004239, HPA008888 Supported Supported Nucleoplasm
Cytosol Liver cancer:4.95e-4 (unfavourable), Endometrial cancer:8.93e-4 (unfavourable) Expressed in all Expressed in all testis: 127.1 Expressed in all +C6orf120 bA160E12.4 ENSG00000185127 Chromosome 6 open reading frame 120 6 169702190-169704856 Predicted secreted proteins Evidence at protein level HPA039626 Uncertain Liver cancer:9.52e-5 (unfavourable), Cervical cancer:2.26e-4 (unfavourable), Ovarian cancer:8.37e-4 (unfavourable) Expressed in all Expressed in all placenta: 28.7 Expressed in all +PURA PUR-ALPHA, PUR1, PURALPHA ENSG00000185129 Purine rich element binding protein A 5 140107777-140125619 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Renal cancer:4.77e-5 (favourable) Expressed in all Mixed parathyroid gland: 26.9 Expressed in all +HIST1H2BL dJ97D16.4, H2B/c, H2BFC ENSG00000185130 Histone cluster 1 H2B family member l 6 27807444-27807931 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed Tissue enriched 6 bone marrow: 3.7 lymph node,thyroid gland: 0.6 Cell line enhanced MOLT-4: 9.8;U-266/84: 8.5 +INPP5J INPP5, PIB5PA, PIPP ENSG00000185133 Inositol polyphosphate-5-phosphatase J 22 31122731-31134696 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034539 Approved Nucleoli
Cytosol Renal cancer:1.12e-7 (favourable), Lung cancer:1.47e-5 (favourable) Tissue enriched Group enriched 10 parathyroid gland: 215.4;thyroid gland: 242.1 small intestine: 22.4 Cell line enhanced HL-60: 15.5;SK-BR-3: 30.3;T-47d: 24.0 +NPY2R ENSG00000185149 Neuropeptide Y receptor Y2 4 155208629-155217078 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced breast: 1.0;cerebral cortex: 1.7;testis: 1.0 rectum: 0.6 Cell line enriched 6 SH-SY5Y: 8.0 +MIXL1 MILD1, MIXL ENSG00000185155 Mix paired-like homeobox 1 226223618-226227054 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005662 Approved Nucleus Tissue enriched Tissue enhanced tonsil: 3.0 lymph node: 2.8 Cell line enhanced HAP1: 1.7;Hep G2: 5.7;U-698: 1.5 +MFSD6L FLJ35773 ENSG00000185156 Major facilitator superfamily domain containing 6 like 17 8797162-8799349 Predicted membrane proteins, Transporters Evidence at transcript level HPA023164 Uncertain Breast cancer:1.84e-4 (favourable) Mixed Tissue enhanced testis: 29.8 parathyroid gland: 8.4 Cell line enriched 5 HMC-1: 7.5 +LRRC37B ENSG00000185158 Leucine rich repeat containing 37B 17 32007872-32053504 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015135 Approved Approved Cytosol Mixed Mixed testis: 32.4 Expressed in all +DDX51 ENSG00000185163 DEAD-box helicase 51 12 132136594-132144335 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039503 Uncertain Approved Nucleus
Nucleoli
Cytosol Liver cancer:4.73e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 11.4 Expressed in all +NOMO2 NOMO, PM5 ENSG00000185164 NODAL modulator 2 16 18417325-18562211 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046697, HPA061174 Approved Expressed in all Expressed in all parathyroid gland: 157.3 Expressed in all +AQP12B INSSA3 ENSG00000185176 Aquaporin 12B 2 240676418-240682906 Predicted membrane proteins Evidence at protein level HPA042216 Supported Not detected Tissue enriched 57 pancreas: 35.7 duodenum: 0.6 Not detected +ZNF479 KR19 ENSG00000185177 Zinc finger protein 479 7 57119614-57139864 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level Not detected Tissue enriched 42 testis: 4.1 all non-specific tissues: 0.0 Not detected +SIGIRR IL-1R8, TIR8 ENSG00000185187 Single Ig and TIR domain containing 11 405716-417455 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023188 Approved Approved Nucleoli fibrillar center
Cytosol Renal cancer:7.61e-6 (favourable), Endometrial cancer:1.34e-5 (favourable), Urothelial cancer:1.54e-5 (favourable), Cervical cancer:7.44e-5 (favourable), Head and neck cancer:9.08e-4 (favourable) Expressed in all Expressed in all spleen: 64.7 Cell line enhanced CAPAN-2: 119.6 +NRBP2 DKFZp434P086 ENSG00000185189 Nuclear receptor binding protein 2 8 143833594-143840974 Enzymes, Predicted intracellular proteins Evidence at protein level CAB020944, HPA029051, HPA029052 Approved Approved Cytosol Renal cancer:2.01e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 55.2 Mixed +PRSS57 PRSSL1, UNQ782 ENSG00000185198 Protease, serine 57 19 685546-695498 Enzymes, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 173 bone marrow: 103.3 spleen: 0.5 Group enriched 9 NB-4: 239.3;THP-1: 126.5 +IFITM2 1-8D ENSG00000185201 Interferon induced transmembrane protein 2 11 307631-315272 Predicted membrane proteins, Transporters Evidence at protein level HPA004337 Uncertain Renal cancer:2.37e-9 (unfavourable) Expressed in all Expressed in all appendix: 705.4 Cell line enhanced HMC-1: 1031.9;HSkMC: 907.1 +TNFAIP2 B94, EXOC3L3 ENSG00000185215 TNF alpha induced protein 2 14 103123442-103137439 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004598, HPA030624 Enhanced Approved Nucleus
Nuclear membrane
Golgi apparatus
Cytosol Stomach cancer:2.79e-5 (favourable), Urothelial cancer:7.17e-5 (favourable), Renal cancer:4.10e-4 (unfavourable) Expressed in all Expressed in all urinary bladder: 203.5 Cell line enhanced RT4: 616.3 +ZNF445 ZKSCAN15, ZNF168, ZSCAN47 ENSG00000185219 Zinc finger protein 445 3 44431720-44477670 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006678 Uncertain Approved Nucleus
Mitochondria
Cytosol Expressed in all Mixed parathyroid gland: 7.2 Mixed +PGBD2 ENSG00000185220 PiggyBac transposable element derived 2 1 248906196-248919946 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029888, HPA029889, HPA029890 Uncertain Supported Vesicles Urothelial cancer:2.05e-4 (favourable), Head and neck cancer:6.08e-4 (favourable), Renal cancer:7.86e-4 (unfavourable) Expressed in all Mixed thyroid gland: 13.4 Expressed in all +TCEAL9 DKFZp313K1940, WBP5, WEX6 ENSG00000185222 Transcription elongation factor A like 9 X 103356452-103358451 Predicted intracellular proteins Evidence at protein level HPA011790 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all placenta: 275.0 Mixed +MC2R ACTHR ENSG00000185231 Melanocortin 2 receptor 18 13882044-13915707 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Not detected Tissue enriched 23 adrenal gland: 50.6 epididymis: 2.1 Not detected +RAB11B H-YPT3 ENSG00000185236 RAB11B, member RAS oncogene family 19 8389981-8404434 Predicted intracellular proteins Evidence at protein level HPA054396 Approved Vesicles
Microtubule organizing center Pancreatic cancer:7.58e-5 (favourable), Renal cancer:2.06e-4 (favourable), Cervical cancer:2.08e-4 (favourable) Expressed in all Expressed in all thyroid gland: 151.9 Expressed in all +PRMT3 HRMT1L3 ENSG00000185238 Protein arginine methyltransferase 3 11 20387530-20509294 Predicted intracellular proteins Evidence at protein level HPA007832, CAB022083 Uncertain Liver cancer:2.81e-5 (unfavourable), Pancreatic cancer:3.17e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 27.4 Expressed in all +GP1BA CD42b, GP1B, GPIbalpha ENSG00000185245 Glycoprotein Ib platelet alpha subunit 17 4932297-4935030 CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002496, HPA013316 Supported Mixed Tissue enhanced lymph node: 17.3 tonsil: 7.1 Cell line enriched 23 HEL: 64.4 +PRPF39 FLJ11128, FLJ20666 ENSG00000185246 Pre-mRNA processing factor 39 14 45084099-45116282 Predicted intracellular proteins Evidence at protein level HPA001176 Approved Approved Nucleoplasm Liver cancer:3.84e-5 (unfavourable), Urothelial cancer:2.99e-4 (favourable), Prostate cancer:4.04e-4 (unfavourable), Melanoma:6.51e-4 (unfavourable), Ovarian cancer:8.48e-4 (favourable) Expressed in all Mixed prostate: 9.8 Expressed in all +MAGEA11 CT1.11, MAGE-11, MAGE11, MAGEA-11, MGC10511 ENSG00000185247 MAGE family member A11 X 149688228-149717266 Predicted intracellular proteins Evidence at protein level HPA052687 Supported Nucleoplasm
Nuclear bodies
Cytosol Mixed Group enriched 15 epididymis: 25.8;testis: 6.9 placenta: 1.0 Cell line enhanced PC-3: 5.2;U-2 OS: 25.0;U-2197: 3.2 +PPIL6 bA425D10.6, dJ919F19.1, MGC41939, RSPH12 ENSG00000185250 Peptidylprolyl isomerase like 6 6 109390215-109441171 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA036717 Approved Approved Nucleus
Golgi apparatus
Cytosol Mixed Tissue enhanced fallopian tube: 53.2;testis: 32.6 thyroid gland: 17.7 Cell line enhanced AN3-CA: 5.4;ASC diff: 6.2;ASC TERT1: 7.8 +ZNF74 Cos52, Zfp520, ZNF520 ENSG00000185252 Zinc finger protein 74 22 20394115-20408461 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003354 Approved Supported Nucleoplasm
Actin filaments Expressed in all Mixed ovary: 4.8 Cell line enhanced K-562: 37.4 +KIAA0825 C5orf36, DKFZp686F0372, MGC34713 ENSG00000185261 KIAA0825 5 94152966-94618597 Predicted intracellular proteins Evidence at protein level HPA038030, HPA038031 Uncertain Not detected Mixed testis: 5.4 Cell line enhanced HeLa: 6.1 +UBALD2 FAM100B, MGC29814 ENSG00000185262 UBA like domain containing 2 17 76265202-76271299 Predicted intracellular proteins Evidence at protein level HPA023046 Uncertain Expressed in all Expressed in all bone marrow: 140.7 Expressed in all +TEX33 C22orf33, EAN57, MGC35206 ENSG00000185264 Testis expressed 33 22 36991120-37007841 Predicted intracellular proteins Evidence at protein level HPA005998 Enhanced Not detected Tissue enriched 574 testis: 87.1 cerebral cortex: 0.1 Not detected +CDNF ARMETL1 ENSG00000185267 Cerebral dopamine neurotrophic factor 10 14819250-14838575 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044587 Uncertain Mixed Tissue enhanced testis: 20.1 skeletal muscle: 12.5 Cell line enhanced RPMI-8226: 8.5 +NOTUM ENSG00000185269 NOTUM, palmitoleoyl-protein carboxylesterase 17 81952507-81961840 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enriched 56 placenta: 192.5 liver: 3.4 Cell line enriched 16 Hep G2: 284.8 +KLHL33 ENSG00000185271 Kelch like family member 33 14 20425870-20435811 Predicted intracellular proteins Evidence at transcript level HPA056560 Uncertain Not detected Tissue enriched 10 skeletal muscle: 30.9 endometrium: 3.1 Cell line enriched 9 REH: 4.3 +RBM11 ENSG00000185272 RNA binding motif protein 11 21 14216130-14228372 Predicted intracellular proteins Evidence at protein level HPA045885 Supported Nucleoplasm Mixed Tissue enriched 17 epididymis: 56.5 cerebral cortex: 3.2 Cell line enhanced HEL: 1.1 +WBSCR17 GalNAc-T5L, GALNTL3 ENSG00000185274 Williams-Beuren syndrome chromosome region 17 7 71132169-71713600 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA013624, HPA047986 Approved Uncertain Nucleus
Nucleoli
Nuclear bodies
Golgi apparatus Testis cancer:3.91e-4 (favourable), Ovarian cancer:4.60e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 76.4 ovary: 29.1 Cell line enhanced AF22: 14.1;NTERA-2: 10.8;RPMI-8226: 8.6;SK-BR-3: 34.1 +ZBTB37 MGC2629, ZNF908 ENSG00000185278 Zinc finger and BTB domain containing 37 1 173868082-173903549 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023438 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Mixed Tissue enhanced testis: 17.0 spleen: 5.3 Mixed +NUPR2 NUPR1L ENSG00000185290 Nuclear protein 2, transcriptional regulator 7 56114681-56116400 Predicted intracellular proteins Evidence at transcript level Renal cancer:9.53e-5 (favourable) Mixed Tissue enriched 13 testis: 112.4 thyroid gland: 8.7 Mixed +IL3RA CD123 ENSG00000185291 Interleukin 3 receptor subunit alpha X 1336616-1382689 CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003539, CAB018374 Approved Cervical cancer:4.27e-4 (favourable), Breast cancer:9.78e-4 (favourable) Expressed in all Mixed lung: 33.2 Cell line enhanced HDLM-2: 109.2;RPMI-8226: 33.2 +SPPL2C IMP5 ENSG00000185294 Signal peptide peptidase like 2C 17 45844835-45847072 Enzymes, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 21 testis: 2.1 all non-specific tissues: 0.0 Not detected +CCDC137 MGC16597 ENSG00000185298 Coiled-coil domain containing 137 17 81666364-81673904 Predicted intracellular proteins Evidence at protein level HPA052637, HPA053914 Uncertain Enhanced Nucleoli Renal cancer:1.16e-7 (unfavourable), Liver cancer:1.35e-7 (unfavourable), Lung cancer:8.32e-4 (unfavourable) Expressed in all Expressed in all skin: 19.7 Expressed in all +SFTPA2 COLEC5, SP-A2 ENSG00000185303 Surfactant protein A2 10 79555852-79560402 Disease related genes, Predicted secreted proteins Evidence at protein level CAB002439, HPA042638, HPA045752, HPA049368 Enhanced Tissue enriched Tissue enriched 383 lung: 15972.2 prostate: 41.7 Group enriched 18 BEWO: 7.1;NB-4: 5.1;RPMI-8226: 17.9;U-2197: 13.9 +RGPD2 RANBP2L2, RGP2 ENSG00000185304 RANBP2-like and GRIP domain containing 2 2 87755955-87825952 Predicted intracellular proteins Evidence at transcript level HPA049497, HPA051675, HPA067564 Uncertain Approved Nuclear membrane
Vesicles Not detected Tissue enhanced placenta: 14.3;testis: 33.3 bone marrow: 6.3 Cell line enhanced BEWO: 10.9;MOLT-4: 10.5;NTERA-2: 5.4;SiHa: 4.7 +ARL15 ARFRP2, FLJ20051 ENSG00000185305 ADP ribosylation factor like GTPase 15 5 53883945-54310582 Predicted intracellular proteins Evidence at protein level HPA044604, HPA063820 Uncertain Approved Golgi apparatus
Plasma membrane
Cell Junctions Expressed in all Expressed in all placenta: 44.8 Mixed +C12orf56 ENSG00000185306 Chromosome 12 open reading frame 56 12 64264762-64391192 Predicted intracellular proteins Evidence at protein level HPA056986 Enhanced Mixed Tissue enriched 21 testis: 15.2 skin: 0.7 Group enriched 13 hTEC/SVTERT24-B: 5.6;SCLC-21H: 5.5 +SCN10A hPN3, Nav1.8, PN3, SNS ENSG00000185313 Sodium voltage-gated channel alpha subunit 10 3 38696802-38794010 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Not detected Not detected testis: 0.3 Not detected +CDK10 PISSLRE ENSG00000185324 Cyclin dependent kinase 10 16 89680737-89696364 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007451, HPA059634, HPA067060 Uncertain Supported Nucleoplasm
Midbody
Midbody ring Pancreatic cancer:2.69e-4 (favourable), Urothelial cancer:3.63e-4 (favourable) Expressed in all Expressed in all thyroid gland: 31.4 Expressed in all +TMEM105 FLJ38792 ENSG00000185332 Transmembrane protein 105 17 81311270-81330674 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced thyroid gland: 1.0 kidney,liver: 0.6 Cell line enhanced CAPAN-2: 2.9;MCF7: 1.1;U-937: 1.8 +SOCS1 Cish1, JAB, SOCS-1, SSI-1, TIP3 ENSG00000185338 Suppressor of cytokine signaling 1 16 11254405-11256179 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB010355, HPA074108 Approved Supported Nucleoplasm
Cytoplasmic bodies Renal cancer:1.08e-6 (unfavourable), Head and neck cancer:1.10e-4 (favourable) Expressed in all Tissue enhanced appendix: 19.3 lymph node: 15.7 Cell line enriched 6 HDLM-2: 102.4 +TCN2 D22S676, D22S750, TC2 ENSG00000185339 Transcobalamin 2 22 30606838-30627278 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000837 Approved Cytosol Liver cancer:2.64e-4 (unfavourable), Cervical cancer:3.47e-4 (favourable) Expressed in all Expressed in all kidney: 122.6 Cell line enhanced ASC TERT1: 84.6;HUVEC TERT2: 123.3;Karpas-707: 137.2 +GAS2L1 GAR22 ENSG00000185340 Growth arrest specific 2 like 1 22 29306582-29312785 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019858 Approved Approved Plasma membrane
Cell Junctions Renal cancer:8.44e-4 (favourable) Expressed in all Expressed in all testis: 32.1 Cell line enhanced U-138 MG: 75.8 +ATP6V0A2 a2, ATP6a2, ATP6N1D, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1 ENSG00000185344 ATPase H+ transporting V0 subunit a2 12 123712318-123761755 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044279 Approved Approved Plasma membrane
Cytosol Expressed in all Expressed in all skin: 15.1 Expressed in all +PARK2 AR-JP, parkin, PDJ ENSG00000185345 Parkin RBR E3 ubiquitin protein ligase 6 161347420-162727771 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016257, HPA036012 Enhanced Supported Nuclear speckles
Cytosol Renal cancer:6.75e-12 (favourable) Mixed Mixed cerebral cortex: 13.8 Cell line enhanced HEL: 4.7;Karpas-707: 2.3;RPMI-8226: 2.3 +C14orf80 ENSG00000185347 Chromosome 14 open reading frame 80 14 105489855-105499575 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039049, HPA039050 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:3.54e-4 (unfavourable) Expressed in all Mixed appendix,skin: 6.6 Mixed +HS6ST3 ENSG00000185352 Heparan sulfate 6-O-sulfotransferase 3 13 96090839-96839562 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA078257 Approved Nucleoplasm
Nuclear membrane
Actin filaments Renal cancer:6.12e-5 (favourable) Mixed Tissue enhanced cerebral cortex: 27.7 urinary bladder: 6.0 Group enriched 8 HAP1: 2.9;RT4: 13.7 +HGS Hrs, Vps27, ZFYVE8 ENSG00000185359 Hepatocyte growth factor-regulated tyrosine kinase substrate 17 81683326-81703138 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004872, HPA007728 Uncertain Enhanced Endosomes
Lysosomes
Cytosol Renal cancer:4.31e-7 (unfavourable), Liver cancer:5.61e-5 (unfavourable), Cervical cancer:4.22e-4 (unfavourable) Expressed in all Expressed in all skin: 85.2 Expressed in all +TNFAIP8L1 MGC17791 ENSG00000185361 TNF alpha induced protein 8 like 1 19 4639518-4655568 Predicted intracellular proteins Evidence at protein level Renal cancer:1.28e-7 (unfavourable) Expressed in all Tissue enhanced fallopian tube: 37.1 spleen: 17.5 Expressed in all +OR2V1 OR2V1P, OST265 ENSG00000185372 Olfactory receptor family 2 subfamily V member 1 5 181124357-181125304 G-protein coupled receptors, Predicted membrane proteins No evidence HPA049953 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +RAD51D HsTRAD, R51H3, RAD51L3, Trad ENSG00000185379 RAD51 paralog D 17 35092208-35121522 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:7.20e-9 (unfavourable), Pancreatic cancer:3.35e-6 (favourable), Endometrial cancer:5.37e-5 (favourable) Expressed in all Mixed cerebral cortex: 9.6 Expressed in all +OR7A17 HTPCRX19 ENSG00000185385 Olfactory receptor family 7 subfamily A member 17 19 14880426-14881452 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected skin,thyroid gland: 0.4 Not detected +MAPK11 p38-2, p38Beta, PRKM11, SAPK2 ENSG00000185386 Mitogen-activated protein kinase 11 22 50263713-50270767 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB012961, HPA045069 Approved Approved Mitochondria Renal cancer:6.02e-6 (unfavourable) Expressed in all Mixed cerebral cortex: 27.7 Mixed +SP140L ENSG00000185404 SP140 nuclear body protein like 2 230327184-230403732 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055864 Uncertain Approved Nucleoplasm Renal cancer:5.09e-10 (unfavourable) Expressed in all Mixed spleen: 28.7 Mixed +MRPL30 MRP-L28, RPML28 ENSG00000185414 Mitochondrial ribosomal protein L30 2 99181079-99197626 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047255 Approved Expressed in all Expressed in all thyroid gland: 20.3 Expressed in all +TARSL2 FLJ25005 ENSG00000185418 Threonyl-tRNA synthetase like 2 15 101653598-101724604 Enzymes, Predicted intracellular proteins Evidence at protein level HPA066697 Approved Approved Cytosol Expressed in all Expressed in all cerebral cortex: 15.7 Expressed in all +SMYD3 KMT3E, ZMYND1, ZNFN3A1 ENSG00000185420 SET and MYND domain containing 3 1 245749342-246507312 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB012229, HPA045821, HPA054352 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all epididymis,thyroid gland: 27.0 Expressed in all +METTL7A DKFZP586A0522 ENSG00000185432 Methyltransferase like 7A 12 50923472-50932517 Predicted membrane proteins Evidence at protein level HPA017434 Supported Lipid droplets Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all thyroid gland: 400.8 Cell line enhanced ASC diff: 267.0;Karpas-707: 287.8;RPMI-8226: 158.7 +IFNLR1 CRF2/12, IFNLR, IL-28R1, IL28RA ENSG00000185436 Interferon lambda receptor 1 1 24154157-24187959 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017319 Uncertain Approved Cytosol Breast cancer:5.12e-4 (favourable) Expressed in all Mixed small intestine: 10.1 Cell line enhanced U-266/70: 39.6;U-698: 28.0 +SH3BGR 21-GARP ENSG00000185437 SH3 domain binding glutamate rich protein 21 39445855-39515506 Predicted intracellular proteins Evidence at protein level CAB003685, HPA030690 Enhanced Approved Plasma membrane
Cytosol Expressed in all Group enriched 6 heart muscle: 100.8;skeletal muscle: 435.9 prostate: 41.4 Cell line enhanced U-87 MG: 100.6 +FAM174B LOC400451, MGC102891 ENSG00000185442 Family with sequence similarity 174 member B 15 92617443-92809884 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015306 Approved Approved Intermediate filaments Endometrial cancer:9.03e-5 (favourable) Expressed in all Mixed thyroid gland: 61.3 Cell line enhanced CACO-2: 61.8;MCF7: 69.4;RPMI-8226: 73.8;RT4: 176.5 +FAM47A MGC27003 ENSG00000185448 Family with sequence similarity 47 member A X 34129756-34132314 Predicted intracellular proteins Evidence at protein level HPA000610 Uncertain Not detected Tissue enriched 56 testis: 5.5 all non-specific tissues: 0.0 Not detected +C19orf68 LOC374920 ENSG00000185453 Chromosome 19 open reading frame 68 19 48170692-48197620 Predicted intracellular proteins Evidence at protein level HPA061028 Uncertain Approved Nucleus Liver cancer:2.35e-5 (unfavourable), Renal cancer:2.44e-4 (favourable) Expressed in all Mixed cerebral cortex: 7.8 Expressed in all +KPNA7 IPOA8 ENSG00000185467 Karyopherin subunit alpha 7 7 99173574-99207506 Predicted intracellular proteins Evidence at protein level HPA031395 Uncertain Mixed Tissue enhanced stomach: 3.1 fallopian tube: 0.9 Cell line enhanced A-431: 1.7;CAPAN-2: 1.2;SK-BR-3: 1.8 +TMEM179B ENSG00000185475 Transmembrane protein 179B 11 62787415-62790405 Predicted membrane proteins, Transporters Evidence at protein level HPA016585, HPA062068 Enhanced Nuclear speckles Expressed in all Expressed in all epididymis: 89.1 Expressed in all +GPRIN3 FLJ42625, GRIN3 ENSG00000185477 GPRIN family member 3 4 89236386-89308010 Predicted intracellular proteins Evidence at protein level HPA043148, HPA057666, HPA059092 Uncertain Approved Nucleus
Nucleoli Colorectal cancer:7.22e-5 (favourable), Renal cancer:8.33e-4 (favourable) Mixed Mixed appendix: 12.0 Cell line enhanced Karpas-707: 73.5;RPMI-8226: 18.9;SCLC-21H: 31.9 +KRT6B KRTL1 ENSG00000185479 Keratin 6B 12 52446651-52452126 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000130, HPA045697, HPA061168 Supported Approved Intermediate filaments Breast cancer:9.44e-4 (favourable), Urothelial cancer:9.52e-4 (unfavourable) Tissue enhanced Tissue enriched 10 esophagus: 670.7 tonsil: 67.0 Cell line enhanced HBEC3-KT: 19.9;hTCEpi: 21.8;RPMI-8226: 9.3 +PARPBP C12orf48, FLJ20641, PARI ENSG00000185480 PARP1 binding protein 12 102120185-102197520 Predicted intracellular proteins Evidence at protein level HPA039677 Approved Supported Nucleoplasm Melanoma:3.17e-4 (unfavourable) Mixed Mixed testis: 7.2 Mixed +STAC3 MGC2793 ENSG00000185482 SH3 and cysteine rich domain 3 12 57243453-57251193 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039285, HPA039527 Enhanced Nucleoplasm
Cytosol Renal cancer:7.11e-6 (unfavourable), Cervical cancer:2.01e-4 (favourable), Colorectal cancer:7.10e-4 (unfavourable) Expressed in all Tissue enriched 24 skeletal muscle: 802.4 prostate: 34.1 Cell line enriched 26 RH-30: 2201.5 +ROR1 NTRKR1 ENSG00000185483 Receptor tyrosine kinase like orphan receptor 1 1 63774022-64181498 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA057016 Uncertain Microtubules
Cytokinetic bridge Mixed Tissue enhanced parathyroid gland: 52.0 endometrium: 12.1 Cell line enhanced ASC TERT1: 35.2;NTERA-2: 43.3 +MUC1 ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM ENSG00000185499 Mucin 1, cell surface associated 1 155185824-155192916 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000036, CAB001986, HPA004179, HPA007235, HPA008855 Enhanced Pancreatic cancer:4.60e-4 (unfavourable) Expressed in all Tissue enhanced lung: 448.0;stomach: 654.1 cervix, uterine: 288.9 Group enriched 7 CAPAN-2: 1005.2;RPTEC TERT1: 654.7;T-47d: 360.0 +FAAP100 C17orf70, FLJ22175 ENSG00000185504 Fanconi anemia core complex associated protein 100 17 81539885-81553961 Predicted intracellular proteins Evidence at protein level HPA023954, HPA024626, HPA026532 Uncertain Enhanced Nucleoplasm
Intermediate filaments
Cytosol Renal cancer:1.00e-7 (unfavourable) Expressed in all Expressed in all spleen: 22.3 Expressed in all +IRF7 ENSG00000185507 Interferon regulatory factor 7 11 612553-615999 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017694, HPA052757 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.71e-10 (unfavourable) Expressed in all Mixed bone marrow: 1.8 Cell line enhanced EFO-21: 3.4;Karpas-707: 4.6;SCLC-21H: 3.7 +L3MBTL1 dJ138B7.3, DKFZp586P1522, KIAA0681, L3MBTL, ZC2HC3 ENSG00000185513 L(3)mbt-like 1 (Drosophila) 20 43507680-43550950 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA068051 Supported Nucleus Mixed Mixed testis: 10.1 Cell line enhanced BEWO: 7.9 +BRCC3 BRCC36, C6.1A, CXorf53 ENSG00000185515 BRCA1/BRCA2-containing complex subunit 3 X 155071420-155123074 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048737 Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 21.2 Expressed in all +SV2B HsT19680, KIAA0735 ENSG00000185518 Synaptic vesicle glycoprotein 2B 15 91099950-91301309 Predicted membrane proteins Evidence at protein level HPA046247 Approved Mixed Tissue enriched 23 cerebral cortex: 47.9 adipose tissue: 2.1 Group enriched 6 RPMI-8226: 1.4;SCLC-21H: 4.6 +FAM131C C1orf117, FLJ36766 ENSG00000185519 Family with sequence similarity 131 member C 1 16057769-16073632 Predicted intracellular proteins Evidence at protein level HPA031046 Uncertain Approved Nucleoli
Intermediate filaments
Cytosol Renal cancer:9.33e-6 (favourable) Mixed Tissue enhanced adrenal gland: 3.3;cerebral cortex: 4.8;kidney: 3.7 heart muscle,skin: 1.1 Cell line enhanced A549: 7.2;HEK 293: 4.6;PC-3: 5.4 +LMNTD2 C11orf35, MGC35138 ENSG00000185522 Lamin tail domain containing 2 11 554855-560779 Predicted intracellular proteins Evidence at protein level HPA058474, HPA073912 Uncertain Approved Cytoplasmic bodies Colorectal cancer:3.75e-4 (unfavourable) Mixed Mixed thyroid gland: 9.4 Cell line enhanced AN3-CA: 4.1;T-47d: 4.6 +SPATA45 C1orf227, LOC149643 ENSG00000185523 Spermatogenesis associated 45 1 212830141-212847649 Predicted intracellular proteins Evidence at transcript level HPA049921 Uncertain Not detected Tissue enriched 11 testis: 13.2 fallopian tube: 1.2 Mixed +PDE6G PDEG, RP57 ENSG00000185527 Phosphodiesterase 6G 17 81650459-81663112 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA045118 Supported Tissue enhanced Tissue enhanced lymph node: 26.1;spleen: 33.3 placenta: 18.9 Cell line enhanced NTERA-2: 10.5;REH: 11.5 +PRKG1 PGK, PKG, PRKG1B, PRKGR1B ENSG00000185532 Protein kinase, cGMP-dependent, type I 10 50991358-52298350 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007699, CAB009629 Enhanced Approved Vesicles
Cytosol Mixed Mixed smooth muscle: 25.1 Cell line enhanced AN3-CA: 19.3;BJ hTERT+: 17.6;fHDF/TERT166: 13.4 +NR2F2 ARP1, COUP-TFII, COUPTFB, NF-E3, SVP40, TFCOUP2 ENSG00000185551 Nuclear receptor subfamily 2 group F member 2 15 96325938-96340263 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058974 Approved Nucleoplasm
Cytosol Expressed in all Tissue enhanced ovary: 360.7 endometrium: 187.1 Mixed +DLK1 Delta1, FA1, pG2, Pref-1, ZOG ENSG00000185559 Delta like non-canonical Notch ligand 1 14 100725705-100738224 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB005872, HPA053879, HPA062262 Supported Approved Golgi apparatus Endometrial cancer:2.31e-4 (unfavourable) Tissue enhanced Group enriched 20 adrenal gland: 1591.0;placenta: 2331.6 ovary: 100.3 Group enriched 6 AF22: 118.4;Hep G2: 282.9;SH-SY5Y: 501.8 +TLCD2 ENSG00000185561 TLC domain containing 2 17 1702790-1710438 Predicted membrane proteins Evidence at transcript level HPA046063 Uncertain Approved Nucleoli
Vesicles Renal cancer:4.36e-5 (unfavourable) Expressed in all Mixed adipose tissue: 6.0 Cell line enhanced SiHa: 6.2 +LSAMP IGLON3, LAMP ENSG00000185565 Limbic system-associated membrane protein 3 115802363-117139389 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054051, HPA076122 Approved Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 102.7 prostate: 43.6 Group enriched 6 AF22: 11.1;SH-SY5Y: 24.0;WM-115: 55.4 +AHNAK2 C14orf78 ENSG00000185567 AHNAK nucleoprotein 2 14 104937244-104978357 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA000878, HPA002940, HPA004145, HPA020111 Enhanced Enhanced Plasma membrane
Cytosol Pancreatic cancer:4.05e-6 (unfavourable), Urothelial cancer:2.23e-5 (unfavourable), Lung cancer:2.79e-5 (unfavourable) Mixed Tissue enriched 7 skin: 345.5 smooth muscle: 46.8 Cell line enhanced hTCEpi: 224.2 +OLFML2A FLJ00237 ENSG00000185585 Olfactomedin like 2A 9 124777158-124814885 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021180, HPA022254 Approved Approved Nucleoplasm
Cytosol Renal cancer:3.73e-5 (unfavourable) Expressed in all Mixed spleen: 47.5 Cell line enhanced ASC TERT1: 112.2;WM-115: 64.5 +SP1 ENSG00000185591 Sp1 transcription factor 12 53380176-53416446 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000330, HPA001853, HPA012292 Supported Enhanced Nucleoplasm Pancreatic cancer:1.43e-4 (unfavourable) Expressed in all Expressed in all endometrium: 54.3 Expressed in all +SPATA8 MGC44294 ENSG00000185594 Spermatogenesis associated 8 15 96783389-96785615 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 1454 testis: 404.5 adrenal gland,gallbladder,placenta: 0.2 Not detected +MRPL40 MRP-L22, NLVCF ENSG00000185608 Mitochondrial ribosomal protein L40 22 19431902-19436075 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA006181 Uncertain Enhanced Nucleoli
Mitochondria Cervical cancer:7.57e-4 (favourable) Expressed in all Expressed in all thyroid gland: 34.8 Expressed in all +DBX2 FLJ16139 ENSG00000185610 Developing brain homeobox 2 12 45014672-45051099 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA066053 Uncertain Tissue enriched Group enriched 5 cerebral cortex: 4.1;testis: 1.2 skin: 0.5 Not detected +FAM212A C3orf54, INKA1 ENSG00000185614 Family with sequence similarity 212 member A 3 49803254-49805030 Predicted intracellular proteins Evidence at protein level HPA041879 Uncertain Approved Nucleoplasm
Vesicles Head and neck cancer:1.96e-4 (favourable) Expressed in all Tissue enhanced skin: 24.4 lung: 7.0 Cell line enhanced HEL: 60.9;HMC-1: 39.3;THP-1: 28.1;U-937: 27.1 +PDIA2 PDA2, PDI, PDIP, PDIR ENSG00000185615 Protein disulfide isomerase family A member 2 16 283152-287215 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051692, HPA053492 Enhanced Approved Nucleoplasm
Cytosol Tissue enriched Tissue enriched 7 pancreas: 523.1 stomach: 71.9 Cell line enhanced HAP1: 4.0;HEK 293: 7.9;Hep G2: 4.4;MCF7: 3.6;SH-SY5Y: 3.9 +PCGF3 DONG1, FLJ36550, MGC40413, RNF3, RNF3A ENSG00000185619 Polycomb group ring finger 3 4 705748-770640 Predicted intracellular proteins Evidence at protein level HPA061879 Supported Nucleoplasm Pancreatic cancer:1.44e-4 (favourable), Head and neck cancer:3.73e-4 (favourable), Urothelial cancer:5.25e-4 (favourable) Expressed in all Expressed in all skin: 62.8 Expressed in all +LMLN Gp63, Msp ENSG00000185621 Leishmanolysin like peptidase 3 197960200-198043720 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016481, HPA028844 Uncertain Supported Focal adhesion sites
Cytosol Endometrial cancer:6.77e-4 (favourable) Expressed in all Tissue enhanced testis: 18.6 epididymis: 13.0 Mixed +P4HB DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB ENSG00000185624 Prolyl 4-hydroxylase subunit beta 17 81843159-81860694 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB012463, HPA018884 Enhanced Supported Endoplasmic reticulum Renal cancer:2.30e-11 (unfavourable) Expressed in all Expressed in all small intestine: 504.4 Expressed in all +PSMD13 p40.5, Rpn9 ENSG00000185627 Proteasome 26S subunit, non-ATPase 13 11 236546-252984 Predicted intracellular proteins Evidence at protein level HPA038691, HPA038692 Approved Approved Nuclear speckles
Cytosol Renal cancer:1.52e-13 (unfavourable), Liver cancer:4.76e-5 (unfavourable), Endometrial cancer:5.74e-4 (favourable) Expressed in all Expressed in all thyroid gland: 41.7 Expressed in all +PBX1 ENSG00000185630 PBX homeobox 1 1 164555584-164899296 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003505, HPA003881, CAB018768 Supported Enhanced Nucleoplasm Mixed Expressed in all endometrium: 248.2 Cell line enhanced SK-BR-3: 173.0 +NDUFA4L2 FLJ26118, NUOMS ENSG00000185633 NDUFA4, mitochondrial complex associated like 2 12 57234903-57240715 Predicted membrane proteins Evidence at protein level HPA055323 Approved Mitochondria Renal cancer:1.37e-5 (unfavourable) Expressed in all Tissue enhanced esophagus: 152.3;skin: 191.7 placenta: 104.2 Cell line enriched 8 AN3-CA: 123.9 +SHC4 RaLP, SHCD ENSG00000185634 SHC adaptor protein 4 15 48823735-48963444 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA074146 Approved Cytosol Tissue enhanced Group enriched 7 cerebral cortex: 13.1;testis: 20.1 gallbladder: 2.3 Cell line enhanced AN3-CA: 9.5;SK-MEL-30: 15.2;WM-115: 16.3 +KRT79 K6L, KRT6L ENSG00000185640 Keratin 79 12 52821410-52834295 Predicted intracellular proteins Evidence at protein level HPA059347 Enhanced Group enriched Group enriched 9 breast: 4.0;skin: 17.1 esophagus: 1.1 Cell line enriched 18 HMC-1: 375.1 +ZFP36L1 Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B ENSG00000185650 ZFP36 ring finger protein like 1 14 68787660-68796253 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001301 Uncertain Expressed in all Expressed in all endometrium: 583.2 Expressed in all +UBE2L3 UBCH7 ENSG00000185651 Ubiquitin conjugating enzyme E2 L3 22 21549447-21624034 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045609, HPA062415 Approved Approved Nucleus
Cytosol Ovarian cancer:3.82e-6 (favourable), Liver cancer:1.29e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 67.1 Expressed in all +NTF3 NGF2 ENSG00000185652 Neurotrophin 3 12 5432112-5521536 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA032001 Approved Mixed Tissue enhanced ovary: 13.5 spleen: 6.2 Cell line enhanced BJ hTERT+: 9.1;BJ hTERT+ SV40 Large T+: 13.6;BJ hTERT+ SV40 Large T+ RasG12V: 18.8;HBF TERT88: 17.3 +BRWD1 C21orf107, DCAF19, FLJ11315, N143, WDR9 ENSG00000185658 Bromodomain and WD repeat domain containing 1 21 39184176-39321559 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030943, HPA030944, HPA030945, CAB034184 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all cerebral cortex: 77.7 Expressed in all +SMIM23 C5orf50, LOC644994 ENSG00000185662 Small integral membrane protein 23 5 171782432-171796126 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 140 testis: 24.9 spleen: 0.1 Not detected +PMEL D12S53E, gp100, Pmel17, SI, SIL, SILV ENSG00000185664 Premelanosome protein 12 55954105-55973317 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA031649 Enhanced Renal cancer:3.70e-4 (favourable) Tissue enriched Tissue enriched 12 skin: 133.4 breast: 10.6 Cell line enriched 55 SK-MEL-30: 6730.3 +SYN3 ENSG00000185666 Synapsin III 22 32512552-33058372 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034566 Uncertain Mixed Tissue enhanced cerebral cortex: 9.5;testis: 7.9 placenta: 4.2 Cell line enhanced HAP1: 5.8;NTERA-2: 3.7;SCLC-21H: 8.6 +POU3F1 OCT6, OTF6, SCIP ENSG00000185668 POU class 3 homeobox 1 1 38044611-38046794 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055980, HPA073824 Enhanced Nucleoplasm Mixed Tissue enriched 14 skin: 23.6 cerebral cortex: 1.6 Group enriched 9 AF22: 12.9;HDLM-2: 22.0;NTERA-2: 6.3;SCLC-21H: 5.3;SK-MEL-30: 15.0 +SNAI3 SMUC, Zfp293, ZNF293 ENSG00000185669 Snail family transcriptional repressor 3 16 88677682-88686493 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA071127 Approved Nucleoplasm Cervical cancer:1.39e-4 (favourable), Pancreatic cancer:3.58e-4 (favourable) Mixed Tissue enhanced skeletal muscle: 10.9 lymph node: 4.3 Cell line enhanced NB-4: 11.5;RPMI-8226: 19.9 +ZBTB3 FLJ23392 ENSG00000185670 Zinc finger and BTB domain containing 3 11 62748319-62754188 Predicted intracellular proteins Evidence at protein level HPA035321, HPA035322 Enhanced Approved Mitochondria Renal cancer:1.65e-5 (favourable), Stomach cancer:9.98e-4 (favourable) Expressed in all Mixed fallopian tube: 7.1 Expressed in all +LYG2 LYGH ENSG00000185674 Lysozyme g2 2 99242246-99255282 Predicted secreted proteins Evidence at protein level HPA039179 Uncertain Mixed Tissue enriched 6 testis: 2.5 skin: 0.4 Cell line enhanced U-937: 1.9 +MORN5 C9orf113, C9orf18, FLJ46909 ENSG00000185681 MORN repeat containing 5 9 122159908-122200088 Predicted intracellular proteins Evidence at transcript level Endometrial cancer:4.86e-4 (favourable) Tissue enhanced Group enriched 6 fallopian tube: 175.5;testis: 106.4 smooth muscle: 24.7 Cell line enhanced NB-4: 1.0;U-87 MG: 1.1 +EP400NL FLJ33915 ENSG00000185684 EP400 N-terminal like 12 132084283-132131639 Predicted intracellular proteins Evidence at protein level HPA068417 Enhanced Expressed in all Tissue enriched 9 testis: 28.7 spleen: 3.1 Mixed +PRAME CT130, MAPE ENSG00000185686 Preferentially expressed antigen in melanoma 22 22547701-22559361 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045153 Enhanced Renal cancer:7.48e-9 (unfavourable), Head and neck cancer:3.41e-4 (unfavourable) Group enriched Group enriched 8 epididymis: 17.1;testis: 80.5 endometrium: 6.3 Cell line enhanced HMC-1: 154.1;K-562: 872.4;SH-SY5Y: 199.7;U-2 OS: 171.5 +C6orf201 dJ1013A10.5 ENSG00000185689 Chromosome 6 open reading frame 201 6 4079209-4130951 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 23 testis: 30.1 fallopian tube: 1.3 Not detected +MYBL1 A-myb, AMYB ENSG00000185697 MYB proto-oncogene like 1 8 66562175-66614247 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008791 Uncertain Renal cancer:2.03e-8 (unfavourable) Mixed Tissue enhanced lymph node: 24.2;testis: 21.4 tonsil: 14.9 Cell line enhanced BJ hTERT+ SV40 Large T+: 76.9;HBF TERT88: 109.4 +C16orf52 ENSG00000185716 Chromosome 16 open reading frame 52 16 22007638-22087534 Predicted membrane proteins Evidence at transcript level Expressed in all Mixed parathyroid gland: 20.1 Expressed in all +DRG1 NEDD3 ENSG00000185721 Developmentally regulated GTP binding protein 1 22 31399523-31530634 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001218 Approved Supported Nuclear bodies
Cytosol Liver cancer:7.71e-4 (unfavourable) Expressed in all Expressed in all testis: 265.1 Expressed in all +ANKFY1 ANKHZN, BTBD23, KIAA1255, RANK-5, ZFYVE14 ENSG00000185722 Ankyrin repeat and FYVE domain containing 1 17 4163907-4263977 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024513, HPA024522, HPA065849 Approved Enhanced Endosomes Expressed in all Expressed in all parathyroid gland: 37.8 Expressed in all +YTHDF3 FLJ31657 ENSG00000185728 YTH N6-methyladenosine RNA binding protein 3 8 63168553-63212786 Predicted intracellular proteins Evidence at protein level HPA048703 Approved Nuclear membrane
Nuclear speckles
Cytosol Expressed in all Expressed in all bone marrow: 59.1 Expressed in all +ZNF696 FLJ14129 ENSG00000185730 Zinc finger protein 696 8 143289676-143298061 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057855, HPA072473 Uncertain Approved Nucleus
Nucleoli Endometrial cancer:3.52e-5 (unfavourable), Cervical cancer:6.63e-5 (unfavourable), Pancreatic cancer:1.41e-4 (favourable) Expressed in all Mixed cerebral cortex: 9.8 Mixed +ADARB2 ADAR3, hRED2, RED2 ENSG00000185736 Adenosine deaminase, RNA specific B2 (inactive) 10 1177318-1737476 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 6 cerebral cortex: 13.1 testis: 2.1 Not detected +NRG3 ENSG00000185737 Neuregulin 3 10 81875314-82987179 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA075789 Approved Vesicles Group enriched Tissue enhanced cerebral cortex: 30.3 fallopian tube: 7.3 Cell line enhanced HEK 293: 1.4;SK-MEL-30: 2.6;U-2 OS: 2.9 +SRL ENSG00000185739 Sarcalumenin 16 4189374-4242080 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041535, HPA045520 Enhanced Group enriched Group enriched 17 heart muscle: 161.0;skeletal muscle: 178.8 esophagus: 10.2 Cell line enriched 11 HSkMC: 2.9 +C11orf87 LOC399947, LOH11CR1A, NEURIM1 ENSG00000185742 Chromosome 11 open reading frame 87 11 109422120-109429114 Predicted membrane proteins Evidence at protein level HPA034656 Approved Tissue enhanced Tissue enriched 20 cerebral cortex: 30.8 endometrium: 1.5 Cell line enhanced BJ hTERT+ SV40 Large T+: 2.7;fHDF/TERT166: 9.0;SCLC-21H: 3.4 +IFIT1 G10P1, GARG-16, IFI56, IFNAI1 ENSG00000185745 Interferon induced protein with tetratricopeptide repeats 1 10 89392546-89406486 Predicted intracellular proteins Evidence at protein level CAB045980, HPA055380 Approved Supported Cytosol Expressed in all Expressed in all spleen: 60.6 Group enriched 5 BJ hTERT+ SV40 Large T+: 746.9;BJ hTERT+ SV40 Large T+ RasG12V: 764.4 +CXorf38 MGC39350 ENSG00000185753 Chromosome X open reading frame 38 X 40626921-40647554 Predicted intracellular proteins Evidence at protein level HPA050120 Approved Supported Cytosol Urothelial cancer:1.44e-8 (favourable), Pancreatic cancer:7.30e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.5 Expressed in all +CLDN24 CLDN21 ENSG00000185758 Claudin 24 4 183321764-183322426 Predicted membrane proteins No evidence Not detected Not detected kidney: 0.8 Not detected +KCNQ5 Kv7.5 ENSG00000185760 Potassium voltage-gated channel subfamily Q member 5 6 72621792-73198851 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA016655 Enhanced Approved Vesicles Mixed Tissue enhanced cerebral cortex: 22.3 thyroid gland: 7.9 Cell line enhanced BJ: 29.6 +ADAMTSL5 THSD6 ENSG00000185761 ADAMTS like 5 19 1505018-1513604 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044050 Approved Golgi apparatus Mixed Tissue enhanced cervix, uterine: 29.0 smooth muscle: 17.4 Mixed +KCNIP4 CALP, KCHIP4, MGC44947 ENSG00000185774 Potassium voltage-gated channel interacting protein 4 4 20728616-21948799 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA022862 Supported Mixed Tissue enhanced cerebral cortex: 57.3 cervix, uterine: 18.9 Cell line enhanced RPTEC TERT1: 4.6;SCLC-21H: 5.6 +SPATA31A6 FAM75A6 ENSG00000185775 SPATA31 subfamily A member 6 9 42183659-42189882 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 16 testis: 1.5 all non-specific tissues: 0.0 Not detected +MORF4L1 Eaf3, HsT17725, MEAF3, MORFRG15, MRG15 ENSG00000185787 Mortality factor 4 like 1 15 78810487-78898133 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042360, HPA062010 Approved Supported Nuclear speckles Expressed in all Expressed in all testis: 1065.7 Expressed in all +NLRP9 CLR19.1, NALP9, NOD6, PAN12 ENSG00000185792 NLR family pyrin domain containing 9 19 55708432-55738402 Predicted intracellular proteins Evidence at transcript level HPA042623 Uncertain Tissue enriched Tissue enhanced prostate: 1.4 testis: 0.6 Not detected +WDR53 MGC12928, MGC64882 ENSG00000185798 WD repeat domain 53 3 196554177-196568674 Predicted intracellular proteins Evidence at protein level HPA016420, HPA019332 Approved Approved Plasma membrane
Cytosol Liver cancer:1.57e-6 (unfavourable), Melanoma:3.09e-4 (unfavourable) Expressed in all Tissue enriched 6 testis: 112.5 parathyroid gland: 19.9 Expressed in all +DMWD D19S593E, DMR-N9, gene59 ENSG00000185800 Dystrophia myotonica, WD repeat containing 19 45782947-45792802 Predicted intracellular proteins Evidence at protein level HPA068172, HPA069843 Approved Approved Plasma membrane
Actin filaments Liver cancer:1.47e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.7 Expressed in all +SLC52A2 D15Ertd747e, FLJ11856, GPCR41, GPR172A, hRFT3, PAR1, RFVT2 ENSG00000185803 Solute carrier family 52 member 2 8 144354135-144361272 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA063036 Approved Liver cancer:2.04e-6 (unfavourable), Renal cancer:1.23e-4 (unfavourable), Cervical cancer:7.55e-4 (unfavourable) Expressed in all Expressed in all placenta: 20.8 Expressed in all +PIGP DCRC, DSCR5, DSRC ENSG00000185808 Phosphatidylinositol glycan anchor biosynthesis class P 21 37059170-37073170 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026921 Uncertain Approved Vesicles Expressed in all Expressed in all epididymis: 125.7 Expressed in all +IKZF1 hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1 ENSG00000185811 IKAROS family zinc finger 1 7 50304124-50405101 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level CAB009247, HPA035221, HPA035222 Enhanced Supported Nucleoplasm Cervical cancer:2.02e-4 (favourable), Breast cancer:4.28e-4 (favourable), Head and neck cancer:8.63e-4 (favourable) Expressed in all Tissue enhanced lymph node: 83.0 tonsil: 55.9 Cell line enhanced HDLM-2: 172.0;HMC-1: 152.5;MOLT-4: 116.9;REH: 122.5;U-698: 108.4 +PCYT2 ET ENSG00000185813 Phosphate cytidylyltransferase 2, ethanolamine 17 81900965-81911464 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023033, HPA023034 Enhanced Supported Intermediate filaments
Centrosome Renal cancer:4.29e-6 (favourable) Expressed in all Expressed in all testis: 241.6 Expressed in all +NAT8L FLJ37478, Hcml3 ENSG00000185818 N-acetyltransferase 8 like 4 2059512-2069089 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040677 Supported Mitochondria Endometrial cancer:1.01e-5 (unfavourable) Group enriched Group enriched 7 adipose tissue: 48.6;cerebral cortex: 64.9;testis: 19.0 kidney: 6.7 Cell line enhanced SCLC-21H: 32.4 +OR6C76 ENSG00000185821 Olfactory receptor family 6 subfamily C member 76 12 55426254-55427192 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +NPAP1 C15orf2 ENSG00000185823 Nuclear pore associated protein 1 15 24675868-24683393 Predicted intracellular proteins, Transporters Evidence at protein level HPA018828, HPA019562 Uncertain Not detected Tissue enriched 11 testis: 5.2 skin: 0.4 Not detected +BCAP31 6C6-Ag, BAP31, CDM, DXS1357E ENSG00000185825 B-cell receptor-associated protein 31 X 153700497-153724697 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA003906, CAB015350, CAB015424 Enhanced Approved Enhanced Endoplasmic reticulum Head and neck cancer:9.87e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 273.7 Expressed in all +ARL17A ARF1P2, ARL17P1 ENSG00000185829 ADP ribosylation factor like GTPase 17A 17 46516702-46579682 Predicted intracellular proteins Evidence at protein level HPA046814 Uncertain Not detected Expressed in all endometrium: 14.1 Mixed +GNB1L GY2, WDR14 ENSG00000185838 G protein subunit beta 1 like 22 19783224-19854939 Predicted intracellular proteins Evidence at protein level HPA034627, HPA034628 Approved Approved Cytosol Expressed in all Mixed duodenum: 4.2 Cell line enhanced K-562: 59.4 +DNAH14 C1orf67, DKFZp781B1548, Dnahc14, HL-18, HL18, MGC27277 ENSG00000185842 Dynein axonemal heavy chain 14 1 224896262-225399292 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027718, HPA028545, HPA031379 Uncertain Approved Centrosome Mixed Tissue enhanced testis: 21.9 thyroid gland: 7.4 Mixed +CCDC190 C1orf110, MGC48998 ENSG00000185860 Coiled-coil domain containing 190 1 162824458-162868815 Predicted intracellular proteins Evidence at transcript level HPA028579, HPA028584, HPA028592 Uncertain Approved Vesicles Mixed Tissue enhanced esophagus: 3.7;lung: 2.8 fallopian tube: 0.8 Cell line enhanced hTEC/SVTERT24-B: 3.9;HUVEC TERT2: 4.0;LHCN-M2: 6.0;TIME: 13.6;U-2197: 8.2 +EVI2B CD361, D17S376, EVDB ENSG00000185862 Ecotropic viral integration site 2B 17 31303766-31314112 CD markers, Predicted membrane proteins Evidence at protein level HPA007436 Enhanced Renal cancer:2.05e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 213.7 lymph node: 175.0 Cell line enhanced HL-60: 77.7;HMC-1: 114.9;Karpas-707: 67.2;RPMI-8226: 98.3;THP-1: 81.9 +TMEM210 ENSG00000185863 Transmembrane protein 210 9 137170858-137172409 Predicted membrane proteins Evidence at protein level HPA066907 Enhanced Tissue enhanced Tissue enriched 11 testis: 10.1 salivary gland: 0.9 Cell line enriched 7 RPMI-8226: 7.9 +NPIPB4 ENSG00000185864 Nuclear pore complex interacting protein family member B4 16 21834569-21880827 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Mixed Expressed in all skin: 124.6 Expressed in all +ZNF829 DKFZp779O175 ENSG00000185869 Zinc finger protein 829 19 36888124-36916291 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA073073 Approved Nucleus
Nuclear bodies Mixed Tissue enriched 5 testis: 18.3 ovary: 3.4 Mixed +TMPRSS11B ENSG00000185873 Transmembrane protease, serine 11B 4 68226653-68245720 Enzymes, Predicted membrane proteins Evidence at protein level Head and neck cancer:6.91e-4 (favourable) Group enriched Group enriched 184 esophagus: 311.6;tonsil: 74.5 cervix, uterine: 1.0 Not detected +THNSL1 FLJ22002, TSH1 ENSG00000185875 Threonine synthase like 1 10 25016658-25026664 Predicted intracellular proteins Evidence at protein level HPA037585 Uncertain Approved Nuclear bodies
Mitochondria
Cytosol Expressed in all Mixed thyroid gland: 14.1 Mixed +TRIM69 RNF36, Trif, TRIMLESS ENSG00000185880 Tripartite motif containing 69 15 44728988-44767829 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028894 Enhanced Renal cancer:2.26e-5 (favourable) Expressed in all Tissue enriched 17 testis: 57.2 cerebral cortex: 3.4 Cell line enhanced Karpas-707: 1.8;U-266/70: 6.7 +ATP6V0C ATP6C, ATP6L, ATPL, VATL, Vma3 ENSG00000185883 ATPase H+ transporting V0 subunit c 16 2513870-2520218 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:1.07e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 422.8 Expressed in all +IFITM1 9-27, CD225, IFI17 ENSG00000185885 Interferon induced transmembrane protein 1 11 313506-315272 CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA004810, CAB017615 Enhanced Supported Cytosol Renal cancer:5.77e-9 (unfavourable) Expressed in all Expressed in all epididymis: 918.5 Cell line enhanced BJ hTERT+ SV40 Large T+: 1313.0;BJ hTERT+ SV40 Large T+ RasG12V: 2441.8 +PRSS38 MPN2 ENSG00000185888 Protease, serine 38 1 227815693-227846470 Enzymes, Predicted secreted proteins Evidence at protein level HPA028003, HPA055809 Enhanced Not detected Tissue enriched 41 testis: 4.2 epididymis: 0.1 Not detected +BPY2C VCY2C ENSG00000185894 Basic charge, Y-linked, 2C Y 25030901-25062548 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 11 testis: 2.1 gallbladder,kidney: 0.1 Not detected +LAMP1 CD107a ENSG00000185896 Lysosomal associated membrane protein 1 13 113297241-113323672 CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB004260, HPA014750 Enhanced Renal cancer:4.15e-5 (favourable) Expressed in all Expressed in all thyroid gland: 211.6 Expressed in all +FFAR3 FFA3R, GPR41 ENSG00000185897 Free fatty acid receptor 3 19 35358460-35360485 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA044681 Uncertain Not detected Tissue enhanced adipose tissue: 2.5;appendix: 3.5;smooth muscle: 2.2 gallbladder: 0.8 Not detected +TAS2R60 T2R60 ENSG00000185899 Taste 2 receptor member 60 7 143443453-143444409 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA030416 Uncertain Not detected Not detected appendix,bone marrow,liver,parathyroid gland,placenta: 0.1 Not detected +POMK FLJ23356, SgK196 ENSG00000185900 Protein-O-mannose kinase 8 43093506-43123434 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA013321 Uncertain Approved Nucleus
Cytosol Mixed Mixed cerebral cortex: 6.2 Expressed in all +C16orf54 FLJ35681 ENSG00000185905 Chromosome 16 open reading frame 54 16 29742463-29746006 Predicted membrane proteins Evidence at protein level HPA060546 Uncertain Expressed in all Tissue enhanced bone marrow: 26.0 lymph node: 23.9 Cell line enhanced HEL: 16.6;HL-60: 15.0;HMC-1: 10.2;MOLT-4: 12.4;THP-1: 14.7 +KLHDC8B MGC35097 ENSG00000185909 Kelch domain containing 8B 3 49171611-49176486 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008463, HPA014467 Supported Enhanced Cytosol Lung cancer:1.47e-4 (favourable) Expressed in all Expressed in all adrenal gland: 70.0 Mixed +KLHL34 FLJ34960, RP11-450P7.3 ENSG00000185915 Kelch like family member 34 X 21654690-21658330 Predicted intracellular proteins Evidence at protein level HPA060287 Uncertain Not detected Tissue enriched 8 skeletal muscle: 8.8 duodenum,heart muscle: 1.1 Not detected +SETD4 C21orf18, C21orf27 ENSG00000185917 SET domain containing 4 21 36034541-36079389 Predicted intracellular proteins Evidence at protein level HPA024073, HPA035405 Approved Approved Nuclear speckles Expressed in all Expressed in all testis: 41.9 Expressed in all +PTCH1 BCNS, NBCCS, PTCH ENSG00000185920 Patched 1 9 95442980-95517057 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013717, HPA075072 Uncertain Approved Golgi apparatus Mixed Tissue enhanced cervix, uterine: 41.7 endometrium: 27.2 Cell line enhanced WM-115: 70.2 +RTN4RL1 DKFZp547J144, NgR3, NGRH2 ENSG00000185924 Reticulon 4 receptor like 1 17 1934677-2025345 Predicted secreted proteins Evidence at protein level HPA044428 Uncertain Renal cancer:7.69e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 12.5 skin: 6.2 Cell line enhanced fHDF/TERT166: 8.4;HaCaT: 9.4;hTCEpi: 7.2;T-47d: 12.5 +OR4C46 ENSG00000185926 Olfactory receptor family 4 subfamily C member 46 11 54603069-54603998 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +CALHM1 FAM26C ENSG00000185933 Calcium homeostasis modulator 1 10 103453387-103458888 Predicted membrane proteins, Transporters Evidence at protein level HPA018317 Uncertain Not detected Tissue enhanced cerebral cortex: 1.8 kidney: 0.6 Cell line enhanced U-266/70: 1.0;U-266/84: 1.2 +KRTAP5-5 KRTAP5-11, KRTAP5.5 ENSG00000185940 Keratin associated protein 5-5 11 1629775-1630707 Predicted intracellular proteins Evidence at transcript level Not detected Not detected epididymis: 0.1 Not detected +NKAIN3 FAM77D, FLJ39630 ENSG00000185942 Sodium/potassium transporting ATPase interacting 3 8 62248591-62999652 Predicted membrane proteins, Transporters Evidence at transcript level HPA018833 Uncertain Tissue enhanced Not detected adrenal gland: 0.4 Cell line enhanced SCLC-21H: 1.7 +RNPC3 FLJ20008, KIAA1839, RBM40, SNRNP65 ENSG00000185946 RNA binding region (RNP1, RRM) containing 3 1 103525691-103555239 Predicted intracellular proteins Evidence at protein level HPA052434 Supported Nucleoplasm Lung cancer:1.53e-4 (favourable), Urothelial cancer:5.25e-4 (favourable), Prostate cancer:7.70e-4 (unfavourable), Pancreatic cancer:7.82e-4 (favourable) Expressed in all Expressed in all epididymis: 67.0 Expressed in all +ZNF267 HZF2 ENSG00000185947 Zinc finger protein 267 16 31873758-31917357 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003866 Approved Approved Nucleoplasm Renal cancer:1.58e-6 (unfavourable) Expressed in all Mixed appendix: 24.9 Expressed in all +IRS2 ENSG00000185950 Insulin receptor substrate 2 13 109752698-109786568 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016944, HPA054664 Approved Supported Aggresome
Cytosol Expressed in all Mixed bone marrow: 32.9 Cell line enhanced SH-SY5Y: 42.7;THP-1: 42.3 +C7orf61 IMAGE:4839025 ENSG00000185955 Chromosome 7 open reading frame 61 7 100456615-100464271 Predicted intracellular proteins Evidence at protein level HPA060395 Enhanced Approved Vesicles Tissue enhanced Tissue enriched 10 testis: 52.9 cerebral cortex: 5.2 Cell line enhanced HUVEC TERT2: 20.9;TIME: 12.0 +FAM186A LOC121006 ENSG00000185958 Family with sequence similarity 186 member A 12 50326230-50396622 Predicted intracellular proteins Evidence at protein level HPA047128 Uncertain Not detected Tissue enriched 19 testis: 10.9 skin: 0.5 Not detected +SHOX GCFX, PHOG, SHOXY, SS ENSG00000185960 Short stature homeobox X 624344-659411 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035141, HPA060931 Enhanced Nucleoplasm
Vesicles Not detected Mixed spleen: 1.0 Cell line enhanced BJ: 19.3;BJ hTERT+: 9.5 +LCE3A LEP13 ENSG00000185962 Late cornified envelope 3A 1 152622834-152623103 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enriched 22 tonsil: 99.1 esophagus: 4.5 Cell line enhanced BJ hTERT+: 2.8;LHCN-M2: 1.2;U-138 MG: 1.7 +BICD2 KIAA0699 ENSG00000185963 BICD cargo adaptor 2 9 92711363-92764812 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023013, HPA024452 Enhanced Supported Golgi apparatus
Plasma membrane
Cytosol Renal cancer:1.39e-4 (favourable) Expressed in all Expressed in all skin: 69.2 Expressed in all +LCE3E LEP17 ENSG00000185966 Late cornified envelope 3E 1 152565654-152566772 Predicted intracellular proteins Evidence at protein level Group enriched Group enriched 35 esophagus: 9.6;skin: 9.0;tonsil: 18.1 breast: 0.3 Not detected +CCIN BTBD20, KBTBD14 ENSG00000185972 Calicin 9 36169394-36171334 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 41 testis: 112.2 smooth muscle: 2.7 Cell line enhanced BJ: 3.3;fHDF/TERT166: 3.7;hTEC/SVTERT24-B: 5.8;TIME: 6.5 +TMLHE BBOX2, FLJ10727, TMLH, XAP130 ENSG00000185973 Trimethyllysine hydroxylase, epsilon X 155490115-155669944 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA034589, HPA040331 Approved Supported Mitochondria Renal cancer:3.68e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 30.7 Mixed +GRK1 GPRK1, RHOK, RK ENSG00000185974 G protein-coupled receptor kinase 1 13 113667155-113737735 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035200, HPA059376 Enhanced Tissue enhanced Not detected thyroid gland: 0.8 Not detected +DEFB128 DEFB-28 ENSG00000185982 Defensin beta 128 20 187853-189681 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 17134 epididymis: 1713.4 all non-specific tissues: 0.0 Not detected +SLITRK2 CXorf2, KIAA1854, SLITL1 ENSG00000185985 SLIT and NTRK like family member 2 X 145817832-145825842 Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 25.7 seminal vesicle: 7.4 Cell line enriched 39 HAP1: 36.6 +PLK5 PLK5P, SgK384ps ENSG00000185988 Polo like kinase 5 19 1524074-1535456 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035024 Enhanced Mixed Tissue enhanced cervix, uterine: 4.5;endometrium: 4.7;testis: 6.9 epididymis: 3.3 Not detected +RASA3 GAP1IP4BP, GAPIII ENSG00000185989 RAS p21 protein activator 3 13 113977783-114132611 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA046759 Uncertain Renal cancer:1.99e-6 (unfavourable) Expressed in all Mixed lymph node: 17.6 Mixed +LRCH3 MGC4126 ENSG00000186001 Leucine rich repeats and calponin homology domain containing 3 3 197791226-197888436 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012380, HPA017299 Uncertain Enhanced Cytosol Liver cancer:2.95e-4 (unfavourable) Expressed in all Expressed in all testis: 26.2 Expressed in all +LEMD1 CT50, LEMP-1 ENSG00000186007 LEM domain containing 1 1 205381378-205457091 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA045425 Approved Nucleoli
Cytosol Ovarian cancer:1.26e-4 (favourable), Pancreatic cancer:1.70e-4 (unfavourable) Tissue enhanced Group enriched 16 epididymis: 18.1;testis: 71.4 fallopian tube: 2.7 Group enriched 6 CAPAN-2: 34.9;NTERA-2: 7.0 +ATP4B ATP6B ENSG00000186009 ATPase H+/K+ transporting beta subunit 13 113648804-113658186 Predicted membrane proteins, Transporters Evidence at protein level HPA045400, HPA052649 Enhanced Tissue enriched Tissue enriched 87 stomach: 953.2 fallopian tube: 10.9 Not detected +NDUFA13 B16.6, CDA016, CGI-39, GRIM-19, GRIM19 ENSG00000186010 NADH:ubiquinone oxidoreductase subunit A13 19 19515736-19529054 Disease related genes, Predicted membrane proteins Evidence at protein level HPA041213 Supported Enhanced Mitochondria Expressed in all Expressed in all heart muscle: 226.3 Expressed in all +ZNF566 FLJ14779, MGC12515 ENSG00000186017 Zinc finger protein 566 19 36445119-36489902 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023456 Uncertain Approved Nucleus Endometrial cancer:1.86e-4 (unfavourable) Expressed in all Mixed thyroid gland: 8.0 Mixed +ZNF529 KIAA1615 ENSG00000186020 Zinc finger protein 529 19 36534774-36605276 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA031311 Uncertain Approved Nucleoplasm Urothelial cancer:1.39e-5 (favourable) Expressed in all Mixed testis: 17.4 Mixed +ZNF284 DKFZp781F1775 ENSG00000186026 Zinc finger protein 284 19 44072144-44089613 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Mixed skin: 3.6 Mixed +HTR3E ENSG00000186038 5-hydroxytryptamine receptor 3E 3 184097064-184106995 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049764 Enhanced Not detected Tissue enhanced duodenum: 1.0 small intestine: 0.8 Cell line enriched 6 RH-30: 1.3 +DLEU7 FLJ44882 ENSG00000186047 Deleted in lymphocytic leukemia, 7 13 50711008-50843939 Predicted intracellular proteins Evidence at transcript level HPA053750 Uncertain Mixed Tissue enriched 7 cerebral cortex: 6.3 epididymis: 0.9 Group enriched 7 NTERA-2: 11.0;U-698: 3.4 +KRT73 K6IRS3, KRT6IRS3 ENSG00000186049 Keratin 73 12 52607570-52618559 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044031 Enhanced Not detected Group enriched 7 lymph node: 2.5;skin: 12.1 appendix: 1.0 Not detected +TAL2 bHLHa19 ENSG00000186051 TAL bHLH transcription factor 2 9 105662457-105663112 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030886 Uncertain Approved Cytosol Renal cancer:2.69e-4 (favourable) Tissue enhanced Group enriched 5 kidney: 3.5;skeletal muscle: 4.8 epididymis: 0.8 Cell line enhanced HAP1: 3.1;K-562: 7.5 +AIDA C1orf80, FLJ12806 ENSG00000186063 Axin interactor, dorsalization associated 1 222668013-222713210 Predicted intracellular proteins Evidence at protein level HPA027935 Approved Approved Microtubules
Cytokinetic bridge
Cytosol Cervical cancer:7.08e-5 (unfavourable), Renal cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all testis: 80.4 Expressed in all +C15orf41 FLJ22851, HH114, MGC11326 ENSG00000186073 Chromosome 15 open reading frame 41 15 36579611-36810248 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA061023 Uncertain Approved Nucleoplasm Mixed Tissue enhanced heart muscle: 63.4 smooth muscle: 14.3 Expressed in all +CD300LF CD300f, CLM1, IGSF13, IREM1, NKIR ENSG00000186074 CD300 molecule like family member f 17 74694311-74712978 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013712 Supported Expressed in all Tissue enhanced lung: 25.6;spleen: 28.0 appendix: 18.2 Group enriched 7 THP-1: 16.6;U-937: 37.2 +ZPBP2 MGC41930, ZPBPL ENSG00000186075 Zona pellucida binding protein 2 17 39868164-39877896 Predicted secreted proteins Evidence at protein level HPA027997, HPA053070 Enhanced Not detected Tissue enriched 230 testis: 209.2 tonsil: 0.9 Cell line enhanced U-698: 3.4 +KRT5 EBS2, KRT5A ENSG00000186081 Keratin 5 12 52514575-52520687 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000027, CAB000129, HPA059479 Enhanced Supported Intermediate filaments Breast cancer:1.27e-4 (favourable) Tissue enhanced Group enriched 9 esophagus: 3256.1;skin: 5996.8 tonsil: 516.9 Group enriched 6 HaCaT: 2557.9;HBEC3-KT: 3723.5;hTCEpi: 8392.0 +NBPF6 ENSG00000186086 Neuroblastoma breakpoint family member 6 1 108450282-108471002 Predicted intracellular proteins Evidence at transcript level HPA045044, HPA046411, HPA047447, HPA058050 Uncertain Tissue enriched Tissue enriched 6 testis: 4.6 placenta,small intestine: 0.7 Cell line enhanced BEWO: 6.2;K-562: 9.6 +GSAP LOC54103, PION ENSG00000186088 Gamma-secretase activating protein 7 77310751-77416400 Predicted intracellular proteins Evidence at protein level HPA023994 Supported Vesicles Urothelial cancer:4.15e-5 (favourable), Breast cancer:3.36e-4 (favourable), Renal cancer:3.51e-4 (unfavourable) Expressed in all Mixed lung: 26.8 Cell line enhanced U-937: 13.1 +HTR3D ENSG00000186090 5-hydroxytryptamine receptor 3D 3 184031544-184039369 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR4F5 ENSG00000186092 Olfactory receptor family 4 subfamily F member 5 1 69091-70008 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +AGBL4 CCP6, FLJ14442 ENSG00000186094 ATP/GTP binding protein like 4 1 48532855-50023913 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA037994 Approved Not detected Tissue enhanced cerebral cortex: 7.9 fallopian tube: 4.6 Cell line enhanced NTERA-2: 1.1;SCLC-21H: 1.9 +ARGFX ENSG00000186103 Arginine-fifty homeobox 3 121570704-121586634 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA043049 Uncertain Tissue enriched Not detected testis: 0.6 Not detected +CYP2R1 ENSG00000186104 Cytochrome P450 family 2 subfamily R member 1 11 14877440-14892252 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042949 Approved Renal cancer:2.86e-4 (unfavourable) Expressed in all Mixed skin: 8.1 Cell line enhanced Karpas-707: 18.6 +LRRC70 LOC100130733, SLRN ENSG00000186105 Leucine rich repeat containing 70 5 62578735-62581448 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013409 Uncertain Mixed Mixed thyroid gland: 6.4 Group enriched 16 HUVEC TERT2: 13.7;TIME: 7.3 +ANKRD46 ENSG00000186106 Ankyrin repeat domain 46 8 100509752-100559784 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013758 Approved Approved Cytosol Expressed in all Expressed in all cerebral cortex: 70.4 Expressed in all +PIP5K1C KIAA0589, LCCS3, PIP5Kgamma ENSG00000186111 Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma 19 3630183-3700479 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017168 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:7.28e-5 (favourable), Cervical cancer:1.79e-4 (favourable), Pancreatic cancer:2.32e-4 (favourable), Renal cancer:3.00e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 52.9 Expressed in all +OR5D14 ENSG00000186113 Olfactory receptor family 5 subfamily D member 14 11 55795556-55796500 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +CYP4F2 ENSG00000186115 Cytochrome P450 family 4 subfamily F member 2 19 15878023-15898120 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014048, HPA017265, HPA058960 Supported Tissue enriched Group enriched 6 duodenum: 78.2;epididymis: 28.0;kidney: 39.3;liver: 84.6;small intestine: 84.3 prostate: 10.4 Cell line enhanced Hep G2: 2.5 +TEX38 ATPAF1-AS1, C1orf223, LOC374973, THEG4 ENSG00000186118 Testis expressed 38 1 46668855-46673594 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 125 testis: 260.8 parathyroid gland: 2.0 Not detected +OR5D18 ENSG00000186119 Olfactory receptor family 5 subfamily D member 18 11 55819630-55820571 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZBTB6 ZID, ZNF482 ENSG00000186130 Zinc finger and BTB domain containing 6 9 122908056-122913330 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054111, HPA076894 Approved Approved Nucleoplasm
Mitochondria Glioma:9.75e-6 (favourable), Renal cancer:5.08e-4 (favourable) Expressed in all Mixed thyroid gland: 12.6 Expressed in all +C2orf76 AIM29, LOC130355, MGC104437 ENSG00000186132 Chromosome 2 open reading frame 76 2 119302225-119366828 Predicted intracellular proteins Evidence at protein level HPA044977, HPA055362 Uncertain Approved Endoplasmic reticulum Renal cancer:2.16e-8 (unfavourable) Expressed in all Expressed in all epididymis: 53.2 Expressed in all +TAS2R42 hT2R55, T2R24, T2R55, TAS2R55 ENSG00000186136 Taste 2 receptor member 42 12 11185993-11186937 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA036149 Uncertain Approved Nucleoplasm
Actin filaments
Focal adhesion sites Not detected Not detected all non-specific tissues: 0.0 Not detected +POLR3C RPC3, RPC62 ENSG00000186141 RNA polymerase III subunit C 1 145824088-145842505 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA027508, HPA027516 Uncertain Enhanced Nucleoplasm Renal cancer:1.85e-5 (unfavourable), Melanoma:1.50e-4 (unfavourable), Endometrial cancer:1.56e-4 (unfavourable), Liver cancer:5.48e-4 (unfavourable) Expressed in all Expressed in all testis: 53.2 Expressed in all +PRR30 C2orf53, MGC44505 ENSG00000186143 Proline rich 30 2 27136848-27139410 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 1041 testis: 104.0 all non-specific tissues: 0.0 Not detected +DEFB131 DEFB-31 ENSG00000186146 Defensin beta 131 4 9444534-9450514 Predicted secreted proteins Evidence at transcript level Tissue enriched Tissue enriched 10 epididymis: 207.2 seminal vesicle: 21.0 Cell line enriched 6 TIME: 1.7 +UBL4B FLJ25690 ENSG00000186150 Ubiquitin like 4B 1 110112468-110113945 Predicted intracellular proteins Evidence at protein level HPA031364 Enhanced Uncertain Intermediate filaments
Mitochondria Tissue enhanced Tissue enriched 61 testis: 69.3 fallopian tube: 1.1 Cell line enriched 5 BJ hTERT+: 16.6 +WWOX FOR, SDR41C1, WOX1 ENSG00000186153 WW domain containing oxidoreductase 16 78099413-79212667 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050992 Approved Supported Golgi apparatus
Cytosol Renal cancer:4.49e-5 (favourable), Breast cancer:9.07e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 33.6 Cell line enhanced MCF7: 65.2 +CYP4Z1 CYP4A20 ENSG00000186160 Cytochrome P450 family 4 subfamily Z member 1 1 47067488-47118319 Enzymes, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enhanced breast: 6.9 lung: 1.5 Group enriched 43 HDLM-2: 8.5;SK-BR-3: 2.8 +CCDC84 DLNB14 ENSG00000186166 Coiled-coil domain containing 84 11 118998142-119015791 Predicted intracellular proteins Evidence at protein level HPA039906, HPA071715 Uncertain Approved Nucleus Renal cancer:2.93e-5 (unfavourable) Expressed in all Mixed skin: 4.6 Mixed +BCL9L DLNB11 ENSG00000186174 B-cell CLL/lymphoma 9-like 11 118893875-118925608 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA049370, HPA053421 Uncertain Enhanced Nucleoplasm Expressed in all Expressed in all placenta: 35.0 Mixed +POLR1D MGC9850, RPA16, RPA9, RPAC2, RPO1-3 ENSG00000186184 RNA polymerase I subunit D 13 27620742-27744237 Disease related genes, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA039337 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all Expressed in all testis: 108.1 Expressed in all +KIF18B ENSG00000186185 Kinesin family member 18B 17 44924709-44947711 Predicted intracellular proteins Evidence at protein level HPA024205 Enhanced Supported Nucleus
Microtubule ends
Cytosol Liver cancer:2.44e-6 (unfavourable), Pancreatic cancer:2.16e-4 (unfavourable), Melanoma:6.90e-4 (unfavourable) Mixed Tissue enhanced bone marrow: 8.4 lymph node: 7.3 Mixed +ZNRF1 DKFZp434E229, FLJ14846, nin283 ENSG00000186187 Zinc and ring finger 1 16 74999030-75110994 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027470 Approved Cervical cancer:9.90e-4 (favourable) Expressed in all Expressed in all testis: 34.3 Expressed in all +FFAR4 GPR120, GPR129, O3FAR1, PGR4 ENSG00000186188 Free fatty acid receptor 4 10 93566665-93604480 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA042563 Uncertain Uncertain Plasma membrane Tissue enhanced Tissue enhanced colon: 8.4;rectum: 12.4 lung: 5.4 Cell line enhanced A549: 1.2;HaCaT: 2.0;NB-4: 1.6 +BPIFB3 C20orf185, dJ726C3.4, LPLUNC3, RYA3 ENSG00000186190 BPI fold containing family B member 3 20 33055424-33073628 Plasma proteins, Predicted secreted proteins Evidence at transcript level HPA045741 Uncertain Tissue enriched Tissue enhanced testis: 1.0 salivary gland: 0.2 Group enriched 28 HEL: 3.3;HMC-1: 2.3 +BPIFB4 C20orf186, dJ726C3.5, LPLUNC4 ENSG00000186191 BPI fold containing family B member 4 20 33079644-33111751 Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced parathyroid gland: 1.3 testis: 0.7 Cell line enhanced HSkMC: 1.7;U-2 OS: 4.0 +SAPCD2 C9orf140, p42.3 ENSG00000186193 Suppressor APC domain containing 2 9 137062124-137070588 Predicted intracellular proteins Evidence at protein level HPA044154 Approved Supported Nucleus
Nucleoli
Cytosol Lung cancer:5.88e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 12.6 small intestine: 4.8 Mixed +EDARADD ENSG00000186197 EDAR associated death domain 1 236348257-236484914 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018836 Uncertain Approved Nucleus
Cytosol Mixed Tissue enhanced urinary bladder: 18.9 seminal vesicle: 11.4 Cell line enhanced HMC-1: 69.7;RT4: 52.5 +SLC51B OSTbeta ENSG00000186198 Solute carrier family 51 beta subunit 15 65045370-65053396 Predicted membrane proteins, Transporters Evidence at protein level HPA008398, HPA008533 Enhanced Approved Vesicles
Mitochondria Renal cancer:8.46e-5 (favourable) Tissue enhanced Tissue enhanced cervix, uterine: 59.7;duodenum: 85.4;small intestine: 118.4 colon: 40.7 Group enriched 9 CACO-2: 15.0;EFO-21: 11.0;Hep G2: 10.4 +CYP4F12 ENSG00000186204 Cytochrome P450 family 4 subfamily F member 12 19 15672757-15697174 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058960 Approved Cervical cancer:1.21e-4 (favourable), Urothelial cancer:2.33e-4 (favourable) Group enriched Tissue enhanced duodenum: 36.2;small intestine: 42.3 skin: 22.3 Cell line enhanced CAPAN-2: 14.8;HaCaT: 26.3;Karpas-707: 14.2;SiHa: 6.0 +MARC1 FLJ22390, MOSC1 ENSG00000186205 Mitochondrial amidoxime reducing component 1 1 220786759-220819657 Predicted intracellular proteins Evidence at protein level HPA028702 Approved Supported Mitochondria Renal cancer:4.51e-4 (unfavourable) Mixed Expressed in all adipose tissue: 225.9 Cell line enhanced BEWO: 149.0;NTERA-2: 65.7 +LCE5A LEP18, SPRL5A ENSG00000186207 Late cornified envelope 5A 1 152510844-152512177 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 6 skin: 94.0 breast: 16.8 Not detected +SOWAHB ANKRD56 ENSG00000186212 Sosondowah ankyrin repeat domain family member B 4 76894928-76898147 Predicted intracellular proteins Evidence at protein level HPA036809, HPA036810 Approved Approved Nucleoli fibrillar center Renal cancer:1.22e-15 (favourable) Mixed Mixed parathyroid gland: 9.1 Cell line enhanced BEWO: 8.3;RT4: 15.1;T-47d: 5.0 +BLOC1S4 BCAS4L, CNO, FLJ11230 ENSG00000186222 Biogenesis of lysosomal organelles complex 1 subunit 4 4 6716055-6717671 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043840 Approved Approved Vesicles
Cytosol Liver cancer:1.06e-4 (unfavourable) Expressed in all Expressed in all ovary: 12.7 Expressed in all +LCE1E LEP5 ENSG00000186226 Late cornified envelope 1E 1 152786214-152788426 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 120 skin: 74.0 breast: 0.6 Cell line enhanced Daudi: 1.3;HaCaT: 8.8;RT4: 1.8 +ZNF749 FLJ16360 ENSG00000186230 Zinc finger protein 749 19 57435329-57445485 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042082, HPA042091, HPA056001 Uncertain Approved Nucleoplasm
Nuclear membrane Expressed in all Mixed parathyroid gland: 4.2 Expressed in all +KLHL32 BKLHD5, KIAA1900 ENSG00000186231 Kelch like family member 32 6 96924620-97140754 Predicted intracellular proteins Evidence at protein level HPA039150 Enhanced Mixed Group enriched 6 cerebral cortex: 25.3;fallopian tube: 10.3 testis: 3.1 Cell line enhanced Daudi: 2.3;HDLM-2: 4.1;SCLC-21H: 2.1;U-266/70: 1.7 +MKL2 FLJ31823, MRTF-B ENSG00000186260 MKL1/myocardin like 2 16 14071321-14266773 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA011286 Supported Supported Nuclear speckles Renal cancer:6.20e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 50.1 Expressed in all +BTLA BTLA1, CD272 ENSG00000186265 B and T lymphocyte associated 3 112463968-112499561 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047211, HPA062029 Enhanced Mixed Group enriched 7 appendix: 14.1;lymph node: 29.3;spleen: 14.6;tonsil: 24.7 urinary bladder: 3.0 Cell line enhanced U-698: 1.3 +ZNF17 FLJ40864, FLJ46058, FLJ46615, HPF3, KIAA1947, KOX10 ENSG00000186272 Zinc finger protein 17 19 57411163-57421939 Predicted intracellular proteins, Transcription factors Evidence at transcript level Pancreatic cancer:6.03e-4 (favourable) Expressed in all Mixed parathyroid gland: 9.3 Expressed in all +KDM4D FLJ10251, JMJD2D ENSG00000186280 Lysine demethylase 4D 11 94973681-94999518 Predicted intracellular proteins Evidence at protein level HPA055854, HPA064037 Approved Approved Nucleoplasm Mixed Tissue enriched 29 testis: 60.7 parathyroid gland: 2.0 Mixed +GPAT2 CT123 ENSG00000186281 Glycerol-3-phosphate acyltransferase 2, mitochondrial 2 96021946-96039451 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036841 Uncertain Approved Mitochondria Mixed Mixed testis: 7.2 Cell line enhanced BJ: 6.9;BJ hTERT+ SV40 Large T+: 18.2;BJ hTERT+ SV40 Large T+ RasG12V: 11.3;U-2 OS: 11.7 +TOR3A ADIR, ADIR2, FLJ22345 ENSG00000186283 Torsin family 3 member A 1 179081377-179098023 Predicted secreted proteins Evidence at protein level HPA028766 Approved Renal cancer:4.78e-8 (unfavourable) Expressed in all Expressed in all lymph node: 39.6 Expressed in all +PABPC1L2A RBM32A ENSG00000186288 Poly(A) binding protein cytoplasmic 1 like 2A X 73077276-73079512 Predicted intracellular proteins Evidence at transcript level HPA041573 Approved Tissue enriched Group enriched 5 adrenal gland: 2.0;cerebral cortex: 6.7;prostate: 3.6;testis: 2.8 epididymis: 0.7 Cell line enhanced HeLa: 2.6;NTERA-2: 1.4 +GABRA5 ENSG00000186297 Gamma-aminobutyric acid type A receptor alpha5 subunit 15 26866363-26949207 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA077031, CAB079022 Supported Supported Plasma membrane Mixed Tissue enriched 43 cerebral cortex: 81.6 esophagus: 1.8 Group enriched 10 A549: 32.7;HAP1: 12.7;NTERA-2: 14.6;U-2 OS: 13.1 +PPP1CC PP1C, PP1gamma ENSG00000186298 Protein phosphatase 1 catalytic subunit gamma 12 110719680-110742939 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022645 Uncertain Liver cancer:2.75e-6 (unfavourable), Cervical cancer:7.44e-4 (favourable) Expressed in all Expressed in all testis: 257.5 Expressed in all +ZNF555 MGC26707 ENSG00000186300 Zinc finger protein 555 19 2841435-2860484 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053956, HPA055430 Uncertain Mixed Mixed testis: 10.4 Mixed +OR10T2 ENSG00000186306 Olfactory receptor family 10 subfamily T member 2 1 158398522-158399466 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Cell line enhanced SCLC-21H: 1.0 +NAP1L3 MB20, MGC26312, NPL3 ENSG00000186310 Nucleosome assembly protein 1 like 3 X 93670930-93673568 Predicted intracellular proteins Evidence at protein level HPA026075 Approved Vesicles Tissue enhanced Tissue enhanced cerebral cortex: 131.3 testis: 31.1 Cell line enhanced AF22: 13.4;HAP1: 13.7;NTERA-2: 24.0;U-2197: 15.0 +PRELID2 FLJ38376, MGC21644 ENSG00000186314 PRELI domain containing 2 5 145471799-145835369 Predicted intracellular proteins Evidence at transcript level HPA042486 Uncertain Approved Nucleoplasm Renal cancer:9.65e-6 (unfavourable), Pancreatic cancer:3.78e-4 (unfavourable) Mixed Tissue enhanced small intestine: 28.7 rectum: 19.2 Mixed +BACE1 BACE ENSG00000186318 Beta-secretase 1 11 117285207-117316259 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB016358 Approved Supported Plasma membrane Urothelial cancer:6.76e-4 (unfavourable) Expressed in all Expressed in all pancreas: 100.7 Mixed +RGS9BP FLJ45744, PERRS, R9AP, RGS9 ENSG00000186326 Regulator of G-protein signaling 9 binding protein 19 32675407-32678300 Disease related genes, Predicted membrane proteins Evidence at protein level HPA049791 Supported Not detected Tissue enriched 6 skeletal muscle: 2.6 lung: 0.4 Cell line enhanced HEL: 4.7 +TMEM212 FLJ23172 ENSG00000186329 Transmembrane protein 212 3 171843349-171938715 Predicted membrane proteins, Transporters Evidence at transcript level HPA045736 Approved Nucleoli fibrillar center
Endoplasmic reticulum Not detected Tissue enriched 6 fallopian tube: 48.3 testis: 8.1 Mixed +SLC36A3 PAT3, TRAMD2, tramdorin2 ENSG00000186334 Solute carrier family 36 member 3 5 151276762-151303766 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Tissue enriched 60 testis: 14.5 epididymis: 0.2 Not detected +SLC36A2 PAT2, TRAMD1, tramdorin ENSG00000186335 Solute carrier family 36 member 2 5 151314978-151347590 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA044002, HPA062229 Enhanced Tissue enriched Group enriched 27 kidney: 67.7;skeletal muscle: 28.0 testis: 1.7 Not detected +THBS2 TSP2 ENSG00000186340 Thrombospondin 2 6 169215780-169254044 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB017716, HPA044304 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Renal cancer:3.77e-6 (unfavourable) Expressed in all Tissue enhanced gallbladder: 113.4 endometrium: 71.2 Cell line enhanced ASC diff: 282.6;ASC TERT1: 196.5;BJ hTERT+ SV40 Large T+ RasG12V: 134.9;hTEC/SVTERT24-B: 150.4 +RXRA NR2B1 ENSG00000186350 Retinoid X receptor alpha 9 134317098-134440585 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004565, CAB005352 Supported Supported Nucleus
Golgi apparatus Renal cancer:5.58e-4 (unfavourable), Pancreatic cancer:7.02e-4 (favourable) Expressed in all Mixed esophagus: 25.8 Mixed +ANKRD37 Lrp2bp ENSG00000186352 Ankyrin repeat domain 37 4 185396021-185400628 Predicted intracellular proteins Evidence at protein level HPA036626, HPA058127 Uncertain Supported Nucleus
Mitochondria
Cytosol Expressed in all Expressed in all esophagus: 31.1 Mixed +C9orf47 bA791O21.3, C9orf108, FLJ37523 ENSG00000186354 Chromosome 9 open reading frame 47 9 88990863-88996140 Predicted secreted proteins Evidence at transcript level CAB009902 Approved Not detected Mixed adrenal gland: 2.1 Cell line enhanced AF22: 2.7;HeLa: 1.6 +NUDT17 FLJ34433 ENSG00000186364 Nudix hydrolase 17 1 145845629-145848953 Predicted intracellular proteins Evidence at protein level HPA030145 Enhanced Approved Centrosome
Cytosol Renal cancer:1.81e-7 (unfavourable), Liver cancer:8.73e-4 (unfavourable) Expressed in all Mixed testis: 5.2 Cell line enhanced T-47d: 11.4 +KIAA1024L ENSG00000186367 KIAA1024 like 5 129748079-129766732 Predicted membrane proteins Evidence at transcript level HPA013760 Uncertain Not detected Tissue enriched 12 skeletal muscle: 11.5 testis: 0.9 Cell line enhanced SH-SY5Y: 1.5 +ZNF75D D8C6, ZKSCAN24, ZNF75, ZNF82, ZSCAN28 ENSG00000186376 Zinc finger protein 75D X 135248920-135344087 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004705 Supported Approved Nucleoplasm
Golgi apparatus Urothelial cancer:7.42e-5 (favourable), Renal cancer:1.31e-4 (favourable) Expressed in all Expressed in all prostate: 15.8 Mixed +CYP4X1 MGC40051 ENSG00000186377 Cytochrome P450 family 4 subfamily X member 1 1 47023568-47050751 Enzymes, Predicted membrane proteins Evidence at protein level HPA017661 Approved Mixed Tissue enhanced cervix, uterine: 52.7 breast: 18.7 Cell line enhanced CACO-2: 3.6;NTERA-2: 2.0;SCLC-21H: 3.0;T-47d: 8.7 +KRT26 KRT25B ENSG00000186393 Keratin 26 17 40766238-40772162 Predicted intracellular proteins Evidence at protein level HPA026890 Supported Not detected Tissue enhanced testis: 1.0 bone marrow: 0.9 Not detected +KRT10 CK10, K10, KPP ENSG00000186395 Keratin 10 17 40818117-40822595 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000132, HPA012014 Enhanced Renal cancer:9.32e-5 (unfavourable) Expressed in all Tissue enriched 31 skin: 18886.8 breast: 612.8 Expressed in all +GOLGA8R ENSG00000186399 Golgin A8 family member R 15 30403740-30414162 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced thyroid gland: 10.5 testis: 5.2 Group enriched 10 HEL: 21.6;THP-1: 5.5;U-937: 7.5 +CD300E CD300LE, CLM2, IREM2 ENSG00000186407 CD300e molecule 17 74609887-74623738 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015570 Uncertain Mixed Tissue enhanced appendix: 52.8;bone marrow: 29.0 adipose tissue: 18.0 Not detected +CCDC30 FLJ20972, LOC728621, PFD6L ENSG00000186409 Coiled-coil domain containing 30 1 42463330-42654664 Predicted intracellular proteins Evidence at protein level HPA036344, HPA036345 Approved Mixed Tissue enhanced testis: 6.9 fallopian tube: 5.0 Cell line enriched 19 HMC-1: 23.7 +NKRF ITBA4, NRF ENSG00000186416 NFKB repressing factor X 119588337-119605895 Predicted intracellular proteins Evidence at protein level HPA001476 Supported Nucleus
Nucleoli Liver cancer:4.92e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 20.3 Expressed in all +GLDN CLOM, COLM, colmedin, CRG-L2, UNC-112 ENSG00000186417 Gliomedin 15 51341629-51408013 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA059441 Uncertain Tissue enhanced Tissue enhanced cerebral cortex: 23.9 adipose tissue: 12.9 Cell line enhanced HHSteC: 2.3;U-266/70: 2.5;U-266/84: 2.0 +FCAR CD89 ENSG00000186431 Fc fragment of IgA receptor 19 54874248-54890472 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014050 Approved Supported Plasma membrane Not detected Tissue enriched 15 bone marrow: 12.3 appendix: 0.8 Not detected +KPNA4 IPOA3, MGC12217, MGC26703, QIP1, SRP3 ENSG00000186432 Karyopherin subunit alpha 4 3 160494995-160565588 Predicted intracellular proteins, Transporters Evidence at protein level CAB034336, HPA043154, HPA045500 Enhanced Enhanced Nucleus Liver cancer:6.24e-7 (unfavourable), Pancreatic cancer:1.03e-6 (unfavourable), Endometrial cancer:8.59e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 36.6 Expressed in all +TRDN ENSG00000186439 Triadin 6 123216339-123637093 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA038226, HPA058226 Enhanced Approved Plasma membrane
Cytosol Tissue enhanced Group enriched 21 heart muscle: 273.5;skeletal muscle: 650.2 prostate: 22.2 Cell line enhanced MCF7: 1.4 +OR6P1 ENSG00000186440 Olfactory receptor family 6 subfamily P member 1 1 158562651-158563604 G-protein coupled receptors, Predicted membrane proteins No evidence HPA047466 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +KRT3 CK3, K3 ENSG00000186442 Keratin 3 12 52789685-52796117 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 6 esophagus: 1.3;skin: 1.8 tonsil: 0.2 Group enriched 8 HaCaT: 8.3;HMC-1: 4.9 +ZNF501 MGC21738, ZNF52 ENSG00000186446 Zinc finger protein 501 3 44729596-44737083 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044161 Uncertain Approved Endoplasmic reticulum Mixed Mixed prostate,testis: 2.7 Mixed +ZNF197 D3S1363E, P18, ZKSCAN9, ZNF166, ZSCAN41 ENSG00000186448 Zinc finger protein 197 3 44584888-44648471 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054567 Uncertain Approved Nucleoplasm Prostate cancer:6.78e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 9.2 Mixed +SPATA12 ENSG00000186451 Spermatogenesis associated 12 3 57060441-57075432 Predicted intracellular proteins Evidence at transcript level HPA043323 Approved Nucleoplasm
Plasma membrane
Cytosol Mixed Tissue enriched 54 testis: 23.0 fallopian tube,lung: 0.4 Not detected +TMPRSS12 CT151, MGC57341 ENSG00000186452 Transmembrane protease, serine 12 12 50842920-50887884 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 75 testis: 39.5 epididymis: 0.5 Not detected +FAM228A C2orf84, FLJ30851 ENSG00000186453 Family with sequence similarity 228 member A 2 24175069-24200849 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 19 testis: 42.4 cerebral cortex: 2.2 Cell line enhanced HHSteC: 2.0;TIME: 3.2 +DEFB132 DEFB32, RP5-1103G7.6 ENSG00000186458 Defensin beta 132 20 257736-261096 Predicted secreted proteins Evidence at transcript level HPA046399 Approved Tissue enhanced Tissue enriched 11 epididymis: 332.3 seminal vesicle: 29.0 Not detected +NAP1L2 BPX, MGC26243 ENSG00000186462 Nucleosome assembly protein 1 like 2 X 73212299-73214848 Predicted intracellular proteins Evidence at protein level HPA054050, HPA057065 Enhanced Vesicles
Plasma membrane
Cytosol Pancreatic cancer:5.41e-4 (favourable) Mixed Tissue enriched 5 cerebral cortex: 90.1 parathyroid gland,prostate: 17.8 Cell line enhanced EFO-21: 15.7;NTERA-2: 18.1;U-2197: 13.6;U-266/84: 21.9 +RPS23 S23 ENSG00000186468 Ribosomal protein S23 5 82273358-82278577 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA054853 Approved Enhanced Endoplasmic reticulum
Cytosol Renal cancer:2.17e-4 (unfavourable), Liver cancer:4.72e-4 (unfavourable) Expressed in all Expressed in all ovary: 4322.3 Expressed in all +GNG2 ENSG00000186469 G protein subunit gamma 2 14 51826195-51979342 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA003534, CAB018380 Uncertain Supported Approved Golgi apparatus
Vesicles Renal cancer:3.90e-6 (unfavourable), Pancreatic cancer:1.64e-4 (favourable) Expressed in all Expressed in all testis: 185.4 Cell line enhanced fHDF/TERT166: 108.6;MOLT-4: 89.8;SH-SY5Y: 94.7;WM-115: 245.1 +BTN3A2 BTN3.2 ENSG00000186470 Butyrophilin subfamily 3 member A2 6 26365159-26378320 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB019392 Uncertain Renal cancer:4.24e-4 (unfavourable) Expressed in all Expressed in all spleen: 129.4 Mixed +AKAP14 AKAP28 ENSG00000186471 A-kinase anchoring protein 14 X 119895837-119920716 Predicted intracellular proteins Evidence at protein level HPA060999 Enhanced Tissue enhanced Group enriched 14 fallopian tube: 67.8;testis: 73.2 lung: 4.8 Cell line enhanced SCLC-21H: 2.9 +PCLO ACZ, DKFZp779G1236, KIAA0559 ENSG00000186472 Piccolo presynaptic cytomatrix protein 7 82754013-83162930 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015858, HPA029579, CAB079012 Approved Approved Approved Nuclear speckles
Plasma membrane Mixed Tissue enhanced cerebral cortex: 17.4 parathyroid gland: 9.8 Group enriched 36 REH: 239.6;U-2 OS: 298.6 +KLK12 KLK-L5 ENSG00000186474 Kallikrein related peptidase 12 19 51029092-51035230 Enzymes, Predicted secreted proteins Evidence at protein level CAB025473 Uncertain Thyroid cancer:8.01e-4 (favourable) Tissue enhanced Tissue enhanced esophagus: 32.4 tonsil: 8.1 Not detected +RGS7BP R7BP ENSG00000186479 Regulator of G-protein signaling 7 binding protein 5 64506257-64612312 Predicted intracellular proteins Evidence at protein level HPA039600 Approved Mixed Tissue enhanced cerebral cortex: 38.9 fallopian tube: 13.2 Cell line enhanced HUVEC TERT2: 9.7;NTERA-2: 2.0;SCLC-21H: 1.5 +INSIG1 CL-6, MGC1405 ENSG00000186480 Insulin induced gene 1 7 155297776-155310235 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA071524 Approved Vesicles Thyroid cancer:9.62e-4 (unfavourable) Expressed in all Expressed in all liver: 281.7 Cell line enhanced Karpas-707: 871.4 +MYT1L KIAA1106, NZF1, ZC2H2C2, ZC2HC4B ENSG00000186487 Myelin transcription factor 1 like 2 1789113-2331260 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060245 Approved Vesicles Not detected Tissue enriched 11 cerebral cortex: 60.0 testis: 5.3 Group enriched 12 SCLC-21H: 7.8;SH-SY5Y: 5.2 +C5orf38 CEI, IRX2NB ENSG00000186493 Chromosome 5 open reading frame 38 5 2752131-2755397 Predicted intracellular proteins Evidence at protein level HPA073667 Enhanced Golgi apparatus
Vesicles Mixed Tissue enhanced lung: 13.7;salivary gland: 13.0 skin: 8.5 Cell line enhanced BEWO: 79.2;hTCEpi: 32.4;SiHa: 37.3 +ZNF396 FLJ31213, ZSCAN14 ENSG00000186496 Zinc finger protein 396 18 35366697-35377337 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006686 Uncertain Mixed Mixed thyroid gland: 14.3 Mixed +TMEM222 C1orf160, DKFZP564D0478 ENSG00000186501 Transmembrane protein 222 1 27322145-27336400 Predicted membrane proteins Evidence at protein level HPA016579, HPA059374 Approved Approved Plasma membrane
Cytosol Expressed in all Expressed in all fallopian tube: 47.9 Expressed in all +OR9Q1 ENSG00000186509 Olfactory receptor family 9 subfamily Q member 1 11 58023881-58181616 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Not detected Not detected skeletal muscle,skin,testis: 0.1 Not detected +CLCNKA hClC-Ka ENSG00000186510 Chloride voltage-gated channel Ka 1 16018875-16034050 Disease related genes, Predicted membrane proteins Evidence at protein level HPA057717 Approved Group enriched Group enriched 9 kidney: 64.2;parathyroid gland: 40.4 thyroid gland: 5.5 Group enriched 11 RPMI-8226: 1.3;SK-BR-3: 1.4;U-266/70: 5.7 +OR9Q2 OR9Q2P ENSG00000186513 Olfactory receptor family 9 subfamily Q member 2 11 58190434-58191518 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.1 Not detected +ARHGAP30 FLJ00267 ENSG00000186517 Rho GTPase activating protein 30 1 161046946-161069970 Predicted intracellular proteins Evidence at protein level HPA036300 Uncertain Supported Vesicles Renal cancer:9.78e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 86.1;spleen: 80.6 appendix: 73.2 Cell line enhanced Daudi: 82.8;HL-60: 72.0;HMC-1: 106.5;U-266/70: 103.3 +SEPT10 FLJ11619 ENSG00000186522 Septin 10 2 109542982-109614206 Predicted intracellular proteins Evidence at protein level HPA047860, HPA056304, HPA060310 Enhanced Enhanced Actin filaments Expressed in all Mixed testis: 140.8 Mixed +FAM86B1 MGC16279 ENSG00000186523 Family with sequence similarity 86 member B1 8 12182096-12194133 Predicted intracellular proteins Evidence at transcript level HPA041610, HPA055718 Uncertain Uncertain Vesicles Mixed Tissue enhanced cerebral cortex: 4.5 endometrium: 2.6 Mixed +CYP4F8 ENSG00000186526 Cytochrome P450 family 4 subfamily F member 8 19 15615218-15630638 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058960 Approved Group enriched Tissue enriched 54 seminal vesicle: 147.7 breast: 2.7 Not detected +CYP4F3 CYP4F, LTB4H ENSG00000186529 Cytochrome P450 family 4 subfamily F member 3 19 15640897-15662825 Enzymes, Predicted intracellular proteins Evidence at protein level HPA058960 Approved Tissue enhanced Tissue enhanced bone marrow: 53.1;liver: 98.0 kidney: 29.4 Group enriched 7 A549: 6.6;CAPAN-2: 28.8;HaCaT: 13.3;Hep G2: 12.4 +SMYD4 KIAA1936, ZMYND21 ENSG00000186532 SET and MYND domain containing 4 17 1779485-1830634 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030059 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles
Cytosol Expressed in all Expressed in all testis: 10.8 Expressed in all +DEFB105A DEFB-5, DEFB105 ENSG00000186562 Defensin beta 105A 8 7821966-7823889 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 5851 epididymis: 2275.4 esophagus: 0.3 Cell line enhanced BEWO: 1.9;NB-4: 5.1;SH-SY5Y: 1.6 +FOXD2 FKHL17, FREAC9 ENSG00000186564 Forkhead box D2 1 47436017-47440691 Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Tissue enhanced colon: 3.4;rectum: 2.7 prostate: 1.1 Cell line enhanced AN3-CA: 11.3;WM-115: 17.4 +GPATCH8 GPATC8, KIAA0553 ENSG00000186566 G-patch domain containing 8 17 44395284-44503430 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044380 Approved Approved Nuclear speckles
Mitochondria Expressed in all Mixed parathyroid gland: 11.7 Mixed +CEACAM19 CEAL1 ENSG00000186567 Carcinoembryonic antigen related cell adhesion molecule 19 19 44662278-44684359 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA014462, HPA052865 Uncertain Approved Nucleus
Nucleoli
Mitochondria Expressed in all Mixed skin: 12.7 Cell line enhanced RPTEC TERT1: 11.9;TIME: 16.9 +DEFB107A DEFB-7, DEFB107 ENSG00000186572 Defensin beta 107A 8 7811720-7815716 Predicted secreted proteins Evidence at transcript level HPA045626 Approved Not detected Tissue enriched 2828 epididymis: 488.6 endometrium: 0.1 Not detected +NF2 ACN, BANF, merlin, SCH ENSG00000186575 Neurofibromin 2 22 29603556-29698598 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003097, CAB005385 Supported Enhanced Nucleus
Plasma membrane
Cytosol Renal cancer:2.89e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 58.7 Expressed in all +C6orf1 LBH, MGC57858 ENSG00000186577 Chromosome 6 open reading frame 1 6 34246380-34249470 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA037659, HPA037660 Uncertain Renal cancer:4.38e-4 (unfavourable), Pancreatic cancer:7.98e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 57.3 Expressed in all +DEFB106A DEFB-6, DEFB106 ENSG00000186579 Defensin beta 106A 8 7825172-7829053 Predicted secreted proteins Evidence at protein level HPA045592 Supported Not detected Not detected all non-specific tissues: 0.0 Cell line enhanced SH-SY5Y: 1.2 +SPATC1 MGC61633, SPATA15, SPERIOLIN ENSG00000186583 Spermatogenesis and centriole associated 1 8 144012414-144047085 Predicted intracellular proteins Evidence at protein level Not detected Group enriched 5 bone marrow: 6.2;testis: 21.7 appendix: 2.5 Cell line enriched 8 U-937: 6.3 +UBE2H GID3, UBC8, UBCH ENSG00000186591 Ubiquitin conjugating enzyme E2 H 7 129830732-129952949 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003302 Approved Supported Mitochondria Pancreatic cancer:2.33e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 94.5 Expressed in all +DEFB105B ENSG00000186599 Defensin beta 105B 8 7487669-7489593 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 18505 epididymis: 1850.5 all non-specific tissues: 0.0 Not detected +HPDL 4-HPPD-L, GLOXD1, MGC15668 ENSG00000186603 4-hydroxyphenylpyruvate dioxygenase like 1 45326905-45328533 Predicted intracellular proteins Evidence at protein level HPA031997, HPA057346 Approved Supported Mitochondria Endometrial cancer:1.60e-5 (unfavourable), Ovarian cancer:1.03e-4 (favourable), Breast cancer:1.81e-4 (favourable) Mixed Mixed colon: 3.8 Cell line enhanced BEWO: 118.1;SK-BR-3: 58.4 +KATNA1 ENSG00000186625 Katanin catalytic subunit A1 6 149594873-149648972 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036207 Approved Supported Nucleus
Microtubule organizing center Liver cancer:3.57e-7 (unfavourable) Expressed in all Expressed in all testis: 80.2 Expressed in all +FSD2 RP11-127F21, SPRYD1 ENSG00000186628 Fibronectin type III and SPRY domain containing 2 15 82755362-82806070 Predicted intracellular proteins Evidence at protein level Not detected Group enriched 21 heart muscle: 34.5;skeletal muscle: 53.5 esophagus: 2.1 Mixed +ARAP1 CENTD2 ENSG00000186635 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 11 72685069-72793599 Predicted intracellular proteins Evidence at protein level CAB020703, HPA070383 Approved Approved Nucleoplasm
Vesicles
Plasma membrane
Cytosol Pancreatic cancer:2.04e-5 (favourable), Thyroid cancer:6.41e-4 (favourable), Liver cancer:6.45e-4 (unfavourable) Expressed in all Expressed in all spleen: 91.3 Expressed in all +KIF24 bA571F15.4, C9orf48, FLJ10933, FLJ43884 ENSG00000186638 Kinesin family member 24 9 34252381-34311371 Predicted intracellular proteins Evidence at protein level HPA020643 Uncertain Cervical cancer:1.33e-4 (favourable) Mixed Tissue enhanced testis: 20.2 fallopian tube: 5.2 Mixed +PDE2A ENSG00000186642 Phosphodiesterase 2A 11 72576141-72674591 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB009752, HPA031192 Enhanced Supported Cytosol Liver cancer:1.76e-6 (favourable) Mixed Tissue enhanced cerebral cortex: 141.8;spleen: 184.3 adipose tissue: 62.1 Cell line enriched 6 HeLa: 340.7 +CARMIL3 BC008134, C14orf121, crml-1, LRRC16B ENSG00000186648 Capping protein regulator and myosin 1 linker 3 14 24052000-24069728 Predicted intracellular proteins Evidence at protein level HPA030596 Uncertain Mixed Tissue enhanced cerebral cortex: 6.7;skin: 6.2 testis: 3.0 Cell line enhanced Daudi: 7.8;HMC-1: 6.5;Karpas-707: 4.8;SCLC-21H: 12.8;SH-SY5Y: 5.6 +PRG2 BMPG, MBP, proMBP ENSG00000186652 Proteoglycan 2, pro eosinophil major basic protein 11 57386794-57390657 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA038515 Supported Not detected Tissue enriched 30 placenta: 3880.8 bone marrow: 130.2 Group enriched 50 HL-60: 2682.8;HMC-1: 4472.2;NB-4: 6716.6 +PRR5 FLJ20185k, PP610, Protor-1 ENSG00000186654 Proline rich 5 22 44668547-44737681 Predicted intracellular proteins Evidence at protein level HPA054072 Approved Endometrial cancer:2.47e-5 (favourable) Expressed in all Mixed spleen: 17.5 Cell line enhanced U-266/70: 75.3 +ZFP91 PZF, ZNF757 ENSG00000186660 ZFP91 zinc finger protein 11 58579111-58621042 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024037, CAB025417, HPA065325 Approved Supported Nucleus
Nucleoli Pancreatic cancer:3.74e-6 (unfavourable) Expressed in all Expressed in all testis: 175.7 Expressed in all +C17orf58 ENSG00000186665 Chromosome 17 open reading frame 58 17 67991101-67996431 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA023036 Uncertain Approved Plasma membrane
Cytosol Renal cancer:1.31e-10 (unfavourable), Liver cancer:8.99e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 50.5 cervix, uterine: 42.4 Expressed in all +BCDIN3D ENSG00000186666 BCDIN3 domain containing RNA methyltransferase 12 49836039-49843129 Predicted intracellular proteins Evidence at protein level HPA039911 Approved Supported Nucleus
Cytosol Renal cancer:1.03e-5 (favourable), Urothelial cancer:1.06e-4 (favourable), Lung cancer:3.24e-4 (favourable) Expressed in all Mixed skeletal muscle: 7.3 Mixed +MAGEE2 HCA3 ENSG00000186675 MAGE family member E2 X 75782988-75785236 Predicted intracellular proteins Evidence at transcript level HPA030625 Uncertain Tissue enriched Group enriched 6 adrenal gland: 1.0;cerebral cortex: 3.3 endometrium,ovary,prostate,rectum,smooth muscle: 0.3 Not detected +CYP27C1 FLJ16008 ENSG00000186684 Cytochrome P450 family 27 subfamily C member 1 2 127184120-127220078 Predicted intracellular proteins Evidence at protein level HPA062460, HPA068731 Supported Vesicles Mixed Tissue enhanced skin: 6.8 cervix, uterine: 2.4 Cell line enhanced HDLM-2: 13.5;TIME: 11.6;U-138 MG: 13.8 +LYRM7 C5orf31, FLJ20796, MZM1L ENSG00000186687 LYR motif containing 7 5 131170810-131205426 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050053 Approved Renal cancer:9.84e-6 (favourable) Expressed in all Mixed testis: 29.9 Expressed in all +CFAP73 CCDC42B, MIA2 ENSG00000186710 Cilia and flagella associated protein 73 12 113149858-113159276 Predicted intracellular proteins Evidence at protein level HPA048539 Enhanced Approved Nucleus
Nucleoli fibrillar center
Vesicles Cervical cancer:1.29e-4 (favourable), Endometrial cancer:5.52e-4 (favourable) Tissue enhanced Tissue enriched 9 fallopian tube: 60.1 lung: 6.9 Cell line enhanced Daudi: 3.1;T-47d: 2.4;U-698: 6.0 +CCDC73 NY-SAR-79 ENSG00000186714 Coiled-coil domain containing 73 11 32602246-32794658 Predicted intracellular proteins Evidence at protein level HPA038668, HPA038669 Uncertain Not detected Tissue enriched 8 testis: 6.7 ovary: 0.8 Cell line enhanced MOLT-4: 1.4 +BCR ALL, BCR1, CML, D22S11, D22S662, PHL ENSG00000186716 BCR, RhoGEF and GTPase activating protein 22 23179704-23318037 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB010421, CAB018545, HPA038337 Approved Approved Nucleoplasm
Cytosol Renal cancer:9.15e-10 (favourable) Expressed in all Mixed cerebral cortex: 47.0 Expressed in all +OR10H1 ENSG00000186723 Olfactory receptor family 10 subfamily H member 1 19 15807003-15808126 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected urinary bladder: 0.7 Cell line enriched 6 RT4: 2.9 +MPPED1 239AB, C22orf1, FAM1A ENSG00000186732 Metallophosphoesterase domain containing 1 22 43411196-43507848 Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 9 cerebral cortex: 39.4 liver: 4.2 Cell line enhanced HaCaT: 5.9;SCLC-21H: 3.1 +FSCN2 RFSN, RP30 ENSG00000186765 Fascin actin-bundling protein 2, retinal 17 81528396-81537130 Disease related genes, Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enhanced parathyroid gland: 4.3;thyroid gland: 2.9 fallopian tube,stomach: 0.8 Cell line enhanced EFO-21: 1.8;T-47d: 1.9 +FOXI2 FLJ46831 ENSG00000186766 Forkhead box I2 10 127737235-127741186 Predicted intracellular proteins, Transcription factors Evidence at transcript level Renal cancer:4.23e-7 (favourable) Tissue enriched Tissue enhanced cervix, uterine: 2.6 kidney: 1.6 Not detected +SPIN4 FLJ44984, TDRD28 ENSG00000186767 Spindlin family member 4 X 63347228-63351344 Predicted intracellular proteins Evidence at protein level HPA044559 Uncertain Approved Nucleoli
Cytosol Renal cancer:3.56e-6 (unfavourable) Expressed in all Mixed placenta: 6.3 Mixed +ZNF732 FLJ59067 ENSG00000186777 Zinc finger protein 732 4 270675-305321 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enhanced Tissue enhanced testis: 2.6 skin: 0.8 Cell line enhanced NTERA-2: 7.2;SH-SY5Y: 1.7 +SPIN2B SPIN-2, TDRD26 ENSG00000186787 Spindlin family member 2B X 57118551-57121546 Predicted intracellular proteins Evidence at transcript level HPA000162, HPA069835 Uncertain Approved Nucleoplasm Renal cancer:1.78e-5 (favourable), Pancreatic cancer:3.39e-4 (favourable), Ovarian cancer:3.43e-4 (favourable) Expressed in all Expressed in all prostate: 18.0 Expressed in all +SPATA31D3 FAM75D3, FLJ44082 ENSG00000186788 SPATA31 subfamily D member 3 9 81943586-81950038 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 78 testis: 7.8 all non-specific tissues: 0.0 Not detected +FOXE3 FKHL12, FREAC8 ENSG00000186790 Forkhead box E3 1 47416072-47418052 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enhanced Not detected testis: 0.5 Not detected +HYAL3 LUCA-3, LUCA14, Minna14 ENSG00000186792 Hyaluronoglucosaminidase 3 3 50292831-50299468 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049402 Uncertain Urothelial cancer:2.12e-5 (unfavourable) Expressed in all Tissue enhanced bone marrow: 22.7 testis: 14.0 Expressed in all +KCNK18 K2p18.1, TRESK, TRESK-2, TRESK2, TRIK ENSG00000186795 Potassium two pore domain channel subfamily K member 18 10 117197489-117210299 Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA044739 Uncertain Not detected Not detected testis: 0.2 Not detected +IFNA10 IFN-alphaC ENSG00000186803 Interferon alpha 10 9 21206181-21207143 Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +VSIG10L ENSG00000186806 V-set and immunoglobulin domain containing 10 like 19 51331536-51342124 Predicted membrane proteins Evidence at protein level HPA060453, HPA066745 Uncertain Enhanced Nucleus Liver cancer:8.75e-4 (unfavourable) Expressed in all Tissue enhanced esophagus: 31.4;salivary gland: 9.2 skin: 5.9 Group enriched 6 Hep G2: 3.2;T-47d: 7.9 +CXCR3 CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR ENSG00000186810 C-X-C motif chemokine receptor 3 X 71615916-71618517 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA045942 Enhanced Renal cancer:1.67e-6 (unfavourable), Endometrial cancer:3.44e-6 (favourable), Melanoma:2.90e-4 (favourable), Head and neck cancer:3.35e-4 (favourable) Mixed Tissue enhanced lymph node: 17.9 spleen: 8.7 Cell line enriched 13 RPMI-8226: 32.7 +ZNF397 MGC13250, ZNF47, ZSCAN15 ENSG00000186812 Zinc finger protein 397 18 35241030-35267133 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026087 Uncertain Approved Nucleoli
Plasma membrane
Microtubules
Cytosol Pancreatic cancer:9.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.8 Mixed +ZSCAN30 ZNF397OS, ZNF917 ENSG00000186814 Zinc finger and SCAN domain containing 30 18 35251058-35290245 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007289 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 26.4 Expressed in all +TPCN1 FLJ20612, KIAA1169, TPC1 ENSG00000186815 Two pore segment channel 1 12 113221050-113298585 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA039757 Approved Expressed in all Expressed in all thyroid gland: 53.5 Expressed in all +LILRB4 CD85k, HM18, ILT3, LIR-5, LIR5 ENSG00000186818 Leukocyte immunoglobulin like receptor B4 19 54643889-54670359 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052807 Approved Expressed in all Tissue enhanced appendix: 14.6;lymph node: 13.4 lung: 8.3 Cell line enriched 33 Karpas-707: 293.0 +TNFRSF4 ACT35, CD134, OX40, TXGP1L ENSG00000186827 TNF receptor superfamily member 4 1 1211326-1214138 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level CAB016128 Enhanced Head and neck cancer:3.50e-6 (favourable), Renal cancer:4.52e-6 (unfavourable), Liver cancer:6.03e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 9.7;appendix: 8.3 lymph node: 7.1 Group enriched 8 MOLT-4: 5.0;NB-4: 7.6 +KRT16 NEPPK ENSG00000186832 Keratin 16 17 41609778-41615899 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000136, HPA000539 Approved Approved Intermediate filaments Pancreatic cancer:1.09e-5 (unfavourable) Group enriched Group enriched 6 esophagus: 477.8;tonsil: 102.4 seminal vesicle: 52.5 Cell line enriched 9 hTCEpi: 593.7 +HEXIM1 CLP-1, EDG1, HIS1, MAQ1 ENSG00000186834 Hexamethylene bisacetamide inducible 1 17 45148502-45152101 Predicted intracellular proteins Evidence at protein level HPA008926, CAB011625 Supported Enhanced Nucleoplasm
Vesicles Expressed in all Expressed in all placenta: 36.2 Expressed in all +SELENOV SELV ENSG00000186838 Selenoprotein V 19 39515113-39520686 Predicted intracellular proteins Evidence at transcript level HPA059274 Uncertain Thyroid cancer:7.43e-4 (unfavourable) Tissue enhanced Group enriched 13 parathyroid gland: 1.8;testis: 5.5;thyroid gland: 2.1 cerebral cortex: 0.2 Not detected +LCE1A LEP1 ENSG00000186844 Late cornified envelope 1A 1 152827473-152827894 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 10 skin: 507.5 breast: 50.5 Not detected +KRT14 EBS3, EBS4 ENSG00000186847 Keratin 14 17 41582279-41586921 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000134, HPA000452, HPA000539, HPA023040 Enhanced Enhanced Intermediate filaments Breast cancer:2.66e-4 (favourable) Group enriched Tissue enriched 19 skin: 7943.3 breast: 421.8 Cell line enhanced HaCaT: 3480.4;HBEC3-KT: 1395.9;hTCEpi: 1722.3;U-2197: 628.5 +TRABD2A C2orf89, TIKI1 ENSG00000186854 TraB domain containing 2A 2 84821650-84907008 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA045817 Approved Group enriched Tissue enhanced colon: 35.4;ovary: 30.7;rectum: 43.1 lymph node: 11.7 Cell line enhanced BEWO: 38.1;HDLM-2: 29.0;hTEC/SVTERT24-B: 17.5;SiHa: 18.3 +KRTAP17-1 KAP17.1 ENSG00000186860 Keratin associated protein 17-1 17 41314917-41315695 Predicted intracellular proteins Evidence at transcript level Not detected Not detected endometrium: 0.1 Group enriched 53 HDLM-2: 8.2;SCLC-21H: 6.3 +PDZD7 bA108L7.8, DFNB57, FLJ23209, PDZK7 ENSG00000186862 PDZ domain containing 7 10 101007683-101031157 Disease related genes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced small intestine: 13.2 cerebral cortex: 8.9 Cell line enhanced SCLC-21H: 16.1;THP-1: 10.8 +POFUT2 C21orf80, FUT13, KIAA0958 ENSG00000186866 Protein O-fucosyltransferase 2 21 45263928-45287898 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044297 Uncertain Renal cancer:8.66e-12 (unfavourable), Colorectal cancer:4.55e-7 (unfavourable), Liver cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all placenta: 24.3 Expressed in all +QRFPR GPR103 ENSG00000186867 Pyroglutamylated RFamide peptide receptor 4 121329312-121381059 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA014300 Uncertain Renal cancer:3.09e-4 (favourable) Tissue enriched Not detected heart muscle: 0.6 Cell line enhanced HL-60: 2.6;hTERT-HME1: 3.2;RPTEC TERT1: 2.0;SCLC-21H: 2.0;U-2 OS: 4.7;WM-115: 2.5 +MAPT DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau ENSG00000186868 Microtubule associated protein tau 17 45894382-46028334 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000151, HPA048895, HPA069524, HPA069570, CAB072344 Enhanced Supported Nuclear speckles
Plasma membrane Group enriched Tissue enriched 8 cerebral cortex: 116.2 skeletal muscle: 13.7 Cell line enhanced HDLM-2: 37.4;SCLC-21H: 16.3;T-47d: 16.5 +ERCC6L FLJ20105, PICH, RAD26L ENSG00000186871 ERCC excision repair 6 like, spindle assembly checkpoint helicase X 72204657-72239047 Enzymes, Predicted intracellular proteins Evidence at protein level HPA050492 Approved Supported Nucleoplasm
Centrosome
Cytosol Breast cancer:1.80e-4 (unfavourable) Tissue enhanced Mixed lymph node: 2.8 Mixed +OR13F1 ENSG00000186881 Olfactory receptor family 13 subfamily F member 1 9 104504263-104505222 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +TMEM17 FLJ34583 ENSG00000186889 Transmembrane protein 17 2 62500221-62511894 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA018100 Uncertain Approved Actin filaments Expressed in all Mixed testis: 8.2 Mixed +TNFRSF18 AITR, CD357, GITR ENSG00000186891 TNF receptor superfamily member 18 1 1203508-1206691 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008025 Approved Renal cancer:4.40e-11 (unfavourable), Endometrial cancer:7.72e-6 (favourable), Head and neck cancer:4.12e-4 (favourable) Expressed in all Tissue enhanced skin: 43.3 parathyroid gland: 18.0 Group enriched 11 RPMI-8226: 148.8;SCLC-21H: 173.4 +FGF3 HBGF-3, INT2 ENSG00000186895 Fibroblast growth factor 3 11 69810224-69819024 Cancer-related genes, Disease related genes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA012692 Approved Approved Group enriched Not detected all non-specific tissues: 0.0 Cell line enriched 89 CAPAN-2: 8.8 +C1QL4 C1QTNF11, CTRP11 ENSG00000186897 Complement C1q like 4 12 49332411-49337188 Predicted secreted proteins Evidence at transcript level Renal cancer:3.03e-5 (unfavourable) Mixed Tissue enhanced testis: 2.1;thyroid gland: 1.2 cerebral cortex: 0.7 Cell line enhanced AN3-CA: 32.7;U-2 OS: 9.6 +RTN4RL2 NgR2, NGRH1 ENSG00000186907 Reticulon 4 receptor-like 2 11 57460549-57477534 Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:3.05e-7 (unfavourable) Expressed in all Group enriched 6 cerebral cortex: 48.7;thyroid gland: 36.2 liver,parathyroid gland: 6.6 Cell line enhanced HMC-1: 38.9;Karpas-707: 48.5;REH: 38.5;RPMI-8226: 93.4 +ZDHHC17 HIP14, HYPH, KIAA0946 ENSG00000186908 Zinc finger DHHC-type containing 17 12 76763588-76853696 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA016807, HPA058674 Approved Supported Golgi apparatus
Vesicles
Aggresome Renal cancer:7.11e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 45.2 Expressed in all +SERPINA11 ENSG00000186910 Serpin family A member 11 14 94442464-94452790 Plasma proteins, Predicted secreted proteins Evidence at protein level Endometrial cancer:6.30e-4 (favourable) Tissue enriched Tissue enriched 30 liver: 255.9 cervix, uterine: 8.6 Cell line enriched 8 Hep G2: 11.7 +P2RY4 NRU, P2P, P2Y4, UNR ENSG00000186912 Pyrimidinergic receptor P2Y4 X 70258170-70259764 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB022644 Uncertain Not detected Tissue enriched 5 small intestine: 3.1 rectum,skin: 0.6 Not detected +ZNF395 DKFZp434K1210, HDBP2, PBF, PRF-1 ENSG00000186918 Zinc finger protein 395 8 28345585-28402701 Predicted intracellular proteins Evidence at protein level HPA049382 Approved Nucleus
Cytosol Renal cancer:5.71e-5 (unfavourable), Liver cancer:1.66e-4 (unfavourable) Expressed in all Expressed in all ovary: 67.0 Expressed in all +ZACN L2, LGICZ, LGICZ1, ZAC, ZAC1 ENSG00000186919 Zinc activated ion channel 17 76071961-76083666 Predicted membrane proteins, Transporters Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP22-1 KAP22.1 ENSG00000186924 Keratin associated protein 22-1 21 30601087-30601382 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP19-6 KAP19.6 ENSG00000186925 Keratin associated protein 19-6 21 30541535-30541864 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP6-2 KAP6.2 ENSG00000186930 Keratin associated protein 6-2 21 30598590-30598902 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR13C8 ENSG00000186943 Olfactory receptor family 13 subfamily C member 8 9 104569168-104570130 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +PPARA hPPAR, NR1C1, PPAR ENSG00000186951 Peroxisome proliferator activated receptor alpha 22 46150521-46243756 FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058901, HPA067049, CAB075701 Supported Enhanced Nucleus Renal cancer:4.39e-9 (favourable) Expressed in all Expressed in all kidney: 24.2 Mixed +TMEM232 FLJ43080 ENSG00000186952 Transmembrane protein 232 5 110289233-110738956 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049386 Uncertain Not detected Tissue enhanced fallopian tube: 26.4;testis: 35.5 thyroid gland: 7.3 Cell line enhanced U-266/70: 2.1 +KRTAP19-2 KAP19.2 ENSG00000186965 Keratin associated protein 19-2 21 30487057-30487436 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP19-4 KAP19.4 ENSG00000186967 Keratin associated protein 19-4 21 30496824-30497133 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP15-1 KAP15.1 ENSG00000186970 Keratin associated protein 15-1 21 30440275-30440945 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP13-4 KAP13.4 ENSG00000186971 Keratin associated protein 13-4 21 30430230-30431026 Predicted intracellular proteins Evidence at protein level Not detected Not detected adrenal gland,parathyroid gland: 0.2 Not detected +FAM183A hCG23177, LOC440585 ENSG00000186973 Family with sequence similarity 183 member A 1 43145153-43156396 Predicted intracellular proteins Evidence at transcript level HPA043382, HPA049120 Approved Tissue enhanced Tissue enriched 14 fallopian tube: 154.3 skin: 11.3 Cell line enhanced CAPAN-2: 3.1;hTCEpi: 1.8;NTERA-2: 3.1;SCLC-21H: 3.1 +EFCAB6 dJ185D5.1, DJBP, FLJ23588, HSCBCIP1, KIAA1672 ENSG00000186976 EF-hand calcium binding domain 6 22 43528744-43812337 Predicted intracellular proteins Evidence at protein level HPA003098 Uncertain Nucleoplasm Mixed Group enriched 5 fallopian tube: 12.3;testis: 44.2 thyroid gland: 5.1 Mixed +KRTAP19-5 KAP19.5 ENSG00000186977 Keratin associated protein 19-5 21 30501657-30502117 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 5 HEK 293: 4.3 +KRTAP23-1 KAP23.1 ENSG00000186980 Keratin associated protein 23-1 21 30348399-30348609 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +KANK3 ANKRD47, FLJ46061 ENSG00000186994 KN motif and ankyrin repeat domains 3 19 8322584-8343262 Predicted intracellular proteins Evidence at protein level HPA051153 Approved Approved Plasma membrane Renal cancer:1.69e-5 (favourable) Expressed in all Tissue enhanced spleen: 24.9 adipose tissue: 22.2 Cell line enhanced HUVEC TERT2: 6.8;TIME: 12.1;U-266/70: 4.5 +EMID1 EMI5, EMU1, hEmu1 ENSG00000186998 EMI domain containing 1 22 29205851-29259597 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA000592 Uncertain Expressed in all Mixed spleen: 30.6 Cell line enhanced HEL: 25.7;NB-4: 63.2 +ACTL7A ENSG00000187003 Actin like 7A 9 108862266-108863759 Predicted intracellular proteins Evidence at protein level HPA021624 Enhanced Not detected Tissue enriched 1938 testis: 193.7 all non-specific tissues: 0.0 Not detected +KRTAP21-1 KAP21.1 ENSG00000187005 Keratin associated protein 21-1 21 30754830-30755428 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 7 breast: 13.5;testis: 6.0 seminal vesicle: 1.3 Cell line enhanced SK-MEL-30: 1.2 +RHD CD240D, DIIIc, RH, Rh30a, Rh4, RhII, RhPI ENSG00000187010 Rh blood group D antigen 1 25272393-25330445 Blood group antigen proteins, CD markers, Predicted membrane proteins, Transporters Evidence at protein level Not detected Tissue enhanced bone marrow: 9.2 skin: 2.5 Group enriched 5 HEL: 33.3;K-562: 10.3 +ESPN DFNB36 ENSG00000187017 Espin 1 6424788-6461370 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028674, HPA060220 Enhanced Approved Vesicles Mixed Tissue enhanced skin: 96.5;testis: 118.3 small intestine: 77.3 Cell line enhanced BEWO: 42.8;SK-BR-3: 110.9;T-47d: 47.8 +PNLIPRP1 PLRP1 ENSG00000187021 Pancreatic lipase related protein 1 10 116590385-116609175 Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 373 pancreas: 2295.1 ovary: 6.1 Not detected +PTRH1 C9orf115, PTH1 ENSG00000187024 Peptidyl-tRNA hydrolase 1 homolog 9 127692978-127724873 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021223 Uncertain Not detected Expressed in all adipose tissue: 11.1 Expressed in all +KRTAP21-2 KAP21.2 ENSG00000187026 Keratin associated protein 21-2 21 30746794-30747233 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 20 skin: 1.1;testis: 2.9 all non-specific tissues: 0.0 Cell line enriched 12 HEK 293: 1.7 +SAMD7 DKFZp686E1583 ENSG00000187033 Sterile alpha motif domain containing 7 3 169911572-169939175 Predicted intracellular proteins Evidence at protein level Not detected Not detected lymph node,testis: 0.2 Not detected +GPR141 PGR13 ENSG00000187037 G protein-coupled receptor 141 7 37683796-37833788 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced bone marrow: 18.5 appendix: 5.6 Cell line enhanced HEL: 11.8;HMC-1: 43.8;NTERA-2: 27.0;U-937: 17.1 +TMPRSS6 FLJ30744 ENSG00000187045 Transmembrane protease, serine 6 22 37065436-37109563 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Liver cancer:8.16e-6 (favourable) Group enriched Group enriched 6 liver: 40.8;testis: 8.6 stomach: 4.0 Cell line enhanced Hep G2: 3.6;SCLC-21H: 10.1 +CYP4A11 CYP4A2, CYP4AII ENSG00000187048 Cytochrome P450 family 4 subfamily A member 11 1 46929177-46941484 Enzymes, Predicted membrane proteins Evidence at protein level Tissue enriched Group enriched 183 kidney: 232.3;liver: 448.3 gallbladder: 1.8 Not detected +TMEM216 CORS2, HSPC244, JBTS2, MGC13379, MKS2 ENSG00000187049 Transmembrane protein 216 11 61391687-61398863 Disease related genes, Predicted membrane proteins Evidence at protein level Expressed in all Mixed ovary: 32.4 Mixed +RPS19BP1 FLJ21770, MGC52010 ENSG00000187051 Ribosomal protein S19 binding protein 1 22 39529093-39532855 Predicted intracellular proteins Evidence at protein level HPA042874 Uncertain Supported Nucleus
Nucleoli
Cytosol Liver cancer:3.71e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 57.2 Expressed in all +TMPRSS11A ECRG1 ENSG00000187054 Transmembrane protease, serine 11A 4 67909385-67964140 Enzymes, Predicted membrane proteins Evidence at protein level Group enriched Group enriched 64 esophagus: 96.0;tonsil: 26.0 cervix, uterine: 0.9 Not detected +TMEM262 ENSG00000187066 Transmembrane protein 262 11 65084979-65089375 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 57 testis: 13.6 cervix, uterine: 0.2 Not detected +C3orf70 ENSG00000187068 Chromosome 3 open reading frame 70 3 185078050-185153014 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA041861 Uncertain Approved Cytosol Renal cancer:6.40e-6 (unfavourable) Tissue enhanced Tissue enhanced smooth muscle: 26.0 cerebral cortex: 19.1 Cell line enhanced SCLC-21H: 23.4;SK-BR-3: 6.5;WM-115: 10.7 +TEAD1 AA, TCF13, TEF-1 ENSG00000187079 TEA domain transcription factor 1 11 12674591-12944483 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057339, HPA062471 Enhanced Nucleoplasm Expressed in all Mixed parathyroid gland: 88.3 Mixed +OR2AK2 OR2AK1P ENSG00000187080 Olfactory receptor family 2 subfamily AK member 2 1 247965233-247966386 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA052544 Uncertain Not detected Not detected testis: 0.2 Not detected +DEFB106B ENSG00000187082 Defensin beta 106B 8 7482504-7486400 Predicted secreted proteins Evidence at protein level HPA045592 Supported Not detected Tissue enriched 18221 epididymis: 2094.6 esophagus: 0.1 Cell line enriched 13 NB-4: 1.3 +PLCD1 ENSG00000187091 Phospholipase C delta 1 3 38007496-38029762 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB009913, HPA020107, HPA021677 Approved Approved Microtubules Renal cancer:9.25e-11 (favourable) Expressed in all Mixed testis: 38.3 Mixed +CCK ENSG00000187094 Cholecystokinin 3 42257825-42266207 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA045039, HPA069515 Enhanced Supported Group enriched Group enriched 5 cerebral cortex: 133.7;duodenum: 116.2;prostate: 31.6 small intestine: 17.7 Group enriched 6 CAPAN-2: 8.5;RPTEC TERT1: 18.9 +ENTPD5 CD39L4, NTPDase-5, PCPH ENSG00000187097 Ectonucleoside triphosphate diphosphohydrolase 5 14 73958010-74019399 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002927 Enhanced Approved Cytosol Renal cancer:3.95e-5 (favourable) Expressed in all Tissue enhanced liver: 130.4 rectum: 111.3 Expressed in all +MITF bHLHe32, MI, WS2, WS2A ENSG00000187098 Melanogenesis associated transcription factor 3 69739435-69968337 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002578, HPA003259 Enhanced Renal cancer:8.35e-10 (favourable) Group enriched Tissue enhanced cervix, uterine: 80.9;endometrium: 79.3 smooth muscle: 69.5 Cell line enhanced HMC-1: 78.7;SK-MEL-30: 205.7 +HEATR4 MGC48595 ENSG00000187105 HEAT repeat containing 4 14 73478484-73558947 Predicted intracellular proteins Evidence at protein level Not detected Group enriched 7 skin: 4.4;testis: 21.6 duodenum,lymph node: 1.9 Cell line enhanced SCLC-21H: 2.9 +NAP1L1 MGC23410, MGC8688, NAP1, NAP1L, NRP ENSG00000187109 Nucleosome assembly protein 1 like 1 12 76036587-76085033 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028861 Approved Uncertain Microtubules Renal cancer:6.14e-13 (unfavourable), Liver cancer:3.29e-9 (unfavourable) Expressed in all Expressed in all ovary: 742.4 Expressed in all +LILRA5 CD85, CD85f, ILT11, LILRB7, LIR9 ENSG00000187116 Leukocyte immunoglobulin like receptor A5 19 54307070-54313139 CD markers, Predicted membrane proteins Evidence at protein level Renal cancer:7.78e-4 (unfavourable) Mixed Tissue enhanced appendix: 13.9;bone marrow: 10.3;spleen: 7.5 urinary bladder: 2.4 Not detected +CMC1 C3orf68, MGC61571 ENSG00000187118 C-X9-C motif containing 1 3 28241584-28325142 Predicted intracellular proteins Evidence at protein level HPA043333 Approved Urothelial cancer:5.52e-4 (favourable), Renal cancer:6.81e-4 (favourable) Expressed in all Expressed in all kidney: 33.5 Expressed in all +SLIT1 MEGF4, SLIL1, Slit-1, slit1, SLIT3 ENSG00000187122 Slit guidance ligand 1 10 96998038-97185920 Predicted secreted proteins Evidence at protein level HPA006879 Approved Plasma membrane Group enriched Tissue enriched 14 cerebral cortex: 60.0 thyroid gland: 4.2 Cell line enriched 11 MOLT-4: 64.7 +LYPD6 MGC52057 ENSG00000187123 LY6/PLAUR domain containing 6 2 149329985-149474148 Predicted secreted proteins Evidence at protein level HPA042805 Uncertain Approved Cytosol Urothelial cancer:2.72e-4 (favourable), Ovarian cancer:3.59e-4 (favourable) Mixed Tissue enhanced gallbladder: 17.3;placenta: 22.5 breast: 12.0 Cell line enhanced AN3-CA: 33.5;fHDF/TERT166: 36.6;LHCN-M2: 38.4;RT4: 30.7 +AKR1C1 DD1, DDH, DDH1, HAKRC, MBAB ENSG00000187134 Aldo-keto reductase family 1 member C1 10 4963253-4983283 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB047303, HPA068265 Uncertain Enhanced Endoplasmic reticulum
Cytosol Renal cancer:8.03e-9 (favourable), Liver cancer:1.56e-4 (unfavourable), Cervical cancer:3.05e-4 (favourable) Tissue enhanced Expressed in all liver: 322.2 Group enriched 7 ASC diff: 2051.8;Hep G2: 3675.4 +VSTM2B ENSG00000187135 V-set and transmembrane domain containing 2B 19 29526499-29564479 Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enriched 20 cerebral cortex: 42.3 cervix, uterine: 2.1 Group enriched 7 SCLC-21H: 1.3;SK-MEL-30: 6.2 +FOXD3 Genesis, HFH2 ENSG00000187140 Forkhead box D3 1 63323041-63325126 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB022455 Uncertain Group enriched Mixed testis: 1.0 Cell line enhanced NTERA-2: 14.7;SK-MEL-30: 9.4;WM-115: 18.2 +SPATA21 spergen-2, spergen2 ENSG00000187144 Spermatogenesis associated 21 1 16387117-16437424 Predicted intracellular proteins Evidence at transcript level HPA032080 Approved Vesicles
Cytosol Not detected Tissue enriched 13 testis: 8.0 skin: 0.6 Cell line enriched 7 Hep G2: 3.7 +RNF220 C1orf164, FLJ10597 ENSG00000187147 Ring finger protein 220 1 44405194-44651724 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027577, HPA027578 Uncertain Approved Nucleus Liver cancer:2.35e-6 (unfavourable), Renal cancer:5.12e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 47.8 Expressed in all +ANGPTL5 ENSG00000187151 Angiopoietin like 5 11 101890674-101916522 Predicted secreted proteins Evidence at protein level HPA038516 Uncertain Not detected Tissue enhanced ovary: 27.1 breast: 7.2 Cell line enhanced ASC diff: 1.8 +SHTN1 KIAA1598, shootin-1, shootin1 ENSG00000187164 Shootin 1 10 116881482-117126586 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA037942, HPA037943 Enhanced Approved Approved Nucleus
Plasma membrane
Cytosol Urothelial cancer:5.08e-6 (unfavourable), Prostate cancer:5.07e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 36.1 parathyroid gland: 18.7 Mixed +H1FNT H1T2, HANP1 ENSG00000187166 H1 histone family member N, testis specific 12 48328980-48330279 Predicted intracellular proteins Evidence at protein level HPA046204 Approved Not detected Tissue enriched 350 testis: 77.1 cerebral cortex: 0.2 Not detected +LCE4A LEP8, SPRL4A ENSG00000187170 Late cornified envelope 4A 1 152708160-152709491 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 6 skin: 5.1 breast: 0.8 Not detected +LCE2A LEP9 ENSG00000187173 Late cornified envelope 2A 1 152698364-152699442 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 13 skin: 146.6 breast: 11.5 Cell line enhanced BJ hTERT+: 4.7;SK-MEL-30: 1.6;U-138 MG: 1.0;U-2197: 1.3 +KRTAP12-1 KAP12.1, KRTAP12.1 ENSG00000187175 Keratin associated protein 12-1 21 44681576-44682163 Predicted intracellular proteins Evidence at protein level Not detected Not detected parathyroid gland,skin: 0.1 Not detected +LCE2C LEP11 ENSG00000187180 Late cornified envelope 2C 1 152675295-152676574 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enriched 10 skin: 283.4 breast: 29.7 Not detected +RP11-195F19.5 ENSG00000187186 9 34664163-34666112 Predicted intracellular proteins Evidence at protein level HPA069617 Enhanced Approved Nucleoli
Endoplasmic reticulum
Vesicles Glioma:5.81e-5 (unfavourable) Mixed Tissue enriched 5 testis: 138.9 cerebral cortex: 25.6 Cell line enhanced HeLa: 31.7 +ZNF546 MGC43537, ZNF49 ENSG00000187187 Zinc finger protein 546 19 39984134-40021041 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030838 Approved Nucleus
Cytosol Mixed Tissue enhanced testis: 14.4 parathyroid gland,thyroid gland: 3.2 Mixed +TSPYL4 dJ486I3.2, KIAA0721 ENSG00000187189 TSPY like 4 6 116249961-116254140 Predicted intracellular proteins Evidence at protein level HPA044863 Approved Renal cancer:5.13e-7 (favourable), Pancreatic cancer:8.46e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 120.8 Mixed +DAZ3 ENSG00000187191 Deleted in azoospermia 3 Y 24763069-24813492 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047113 Approved Not detected Tissue enriched 11 testis: 1.0 all non-specific tissues: 0.0 Not detected +MT1X MT-1l, MT1 ENSG00000187193 Metallothionein 1X 16 56682424-56684196 Predicted intracellular proteins Evidence at protein level Renal cancer:1.82e-10 (unfavourable) Expressed in all Expressed in all thyroid gland: 1347.9 Expressed in all +GCNT1 C2GNT, NACGT2, NAGCT2 ENSG00000187210 Glucosaminyl (N-acetyl) transferase 1, core 2 9 76419850-76507416 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003522, HPA003523, HPA031151 Uncertain Supported Nuclear speckles Urothelial cancer:4.96e-4 (unfavourable), Endometrial cancer:8.44e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 186.4 duodenum: 50.1 Cell line enhanced HHSteC: 38.9 +LCE2D LEP12, SPRL1A ENSG00000187223 Late cornified envelope 2D 1 152663396-152664659 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enriched 14 skin: 136.2 breast: 9.9 Not detected +SESTD1 DKFZp434O0515, Solo ENSG00000187231 SEC14 and spectrin domain containing 1 2 179101692-179264790 Predicted intracellular proteins Evidence at protein level HPA058236, HPA077408 Enhanced Intermediate filaments Renal cancer:2.78e-11 (favourable), Liver cancer:1.88e-4 (unfavourable), Stomach cancer:2.67e-4 (unfavourable) Expressed in all Mixed testis: 16.9 Mixed +LCE3B LEP14 ENSG00000187238 Late cornified envelope 3B 1 152613811-152614098 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 29 tonsil: 2.8 all non-specific tissues: 0.0 Not detected +FNBP1 FBP17, KIAA0554 ENSG00000187239 Formin binding protein 1 9 129887187-130043194 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019635, HPA019691, HPA022119 Enhanced Renal cancer:8.45e-5 (unfavourable) Expressed in all Expressed in all lymph node: 90.7 Mixed +DYNC2H1 DHC1b, DHC2, DNCH2, DYH1B, hdhc11 ENSG00000187240 Dynein cytoplasmic 2 heavy chain 1 11 103109431-103479863 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039015, HPA039016 Approved Supported Mitochondria Renal cancer:8.49e-5 (favourable) Mixed Mixed parathyroid gland: 17.4 Mixed +KRT12 K12 ENSG00000187242 Keratin 12 17 40861303-40867210 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055217, HPA055835 Enhanced Mixed Not detected small intestine: 0.7 Not detected +MAGED4B ENSG00000187243 MAGE family member D4B X 52061827-52069248 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003554 Approved Not detected Tissue enhanced cerebral cortex: 35.1 endometrium: 13.8 Cell line enhanced AF22: 48.8;NTERA-2: 40.6 +BCAM CD239, LU ENSG00000187244 Basal cell adhesion molecule (Lutheran blood group) 19 44809059-44821420 Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005654 Uncertain Approved Nucleoli fibrillar center Renal cancer:5.94e-6 (favourable), Endometrial cancer:1.24e-5 (unfavourable), Colorectal cancer:2.31e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 174.7 Cell line enhanced HaCaT: 278.4;SK-BR-3: 217.2;T-47d: 152.4 +RSBN1L FLJ42526, FLJ45813, MGC71764 ENSG00000187257 Round spermatid basic protein 1 like 7 77696443-77783022 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA020406, HPA020413 Approved Supported Nuclear speckles
Plasma membrane Lung cancer:3.74e-4 (favourable) Expressed in all Expressed in all testis: 46.7 Expressed in all +NPSR1 GPR154, GPRA, PGR14 ENSG00000187258 Neuropeptide S receptor 1 7 34658239-34878332 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA007489 Supported Tissue enhanced Not detected stomach: 0.5 Cell line enhanced HAP1: 1.1 +WDR86 ENSG00000187260 WD repeat domain 86 7 151375909-151410727 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enhanced parathyroid gland: 20.9;spleen: 14.3 endometrium: 7.5 Group enriched 5 HSkMC: 9.9;NTERA-2: 2.6;SCLC-21H: 6.9;SH-SY5Y: 4.4 +EPOR ENSG00000187266 Erythropoietin receptor 19 11377205-11384342 Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA077613 Supported Vesicles Pancreatic cancer:3.17e-5 (favourable) Expressed in all Tissue enhanced parathyroid gland: 53.1 thyroid gland: 18.0 Mixed +FAM9C TEX39C ENSG00000187268 Family with sequence similarity 9 member C X 13035618-13044682 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 7 spleen: 54.4 testis: 8.1 Cell line enriched 56 AN3-CA: 169.6 +KRTAP9-8 KAP9.8 ENSG00000187272 Keratin associated protein 9-8 17 41238045-41239004 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 15 HDLM-2: 1.5 +CIDEC CIDE-3, FLJ20871, Fsp27 ENSG00000187288 Cell death inducing DFFA like effector c 3 9866711-9880254 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018837, HPA020553 Approved Mixed Tissue enriched 8 adipose tissue: 761.8 small intestine: 99.2 Cell line enhanced ASC diff: 1149.6;ASC TERT1: 262.9;HSkMC: 164.2 +DCC IGDCC1, NTN1R1 ENSG00000187323 DCC netrin 1 receptor 18 52340172-53535903 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055376, HPA069552 Supported Supported Golgi apparatus Tissue enhanced Tissue enhanced cerebral cortex: 3.7;testis: 13.5 lung: 2.2 Cell line enhanced AF22: 36.0;U-266/70: 85.8;U-266/84: 39.7 +TAF9B DN-7, DN7, TAF9L, TAFII31L, TFIID-31 ENSG00000187325 TATA-box binding protein associated factor 9b X 78129748-78139706 Predicted intracellular proteins Evidence at protein level HPA045275 Approved Cervical cancer:5.40e-5 (favourable) Expressed in all Expressed in all smooth muscle: 43.8 Expressed in all +PCDHB13 PCDH-BETA13 ENSG00000187372 Protocadherin beta 13 5 141213919-141218979 Plasma proteins, Predicted membrane proteins Evidence at transcript level Mixed Mixed endometrium,gallbladder: 2.5 Cell line enhanced EFO-21: 6.9;T-47d: 13.5;U-2197: 10.8 +MAGI2 ACVRIP1, AIP1, ARIP1, KIAA0705, MAGI-2 ENSG00000187391 Membrane associated guanylate kinase, WW and PDZ domain containing 2 7 78017057-79453574 Predicted intracellular proteins Evidence at protein level HPA013650 Approved Renal cancer:1.08e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 46.2;parathyroid gland: 38.6 prostate: 14.0 Group enriched 5 AF22: 19.3;Karpas-707: 58.7 +LUZP2 ENSG00000187398 Leucine zipper protein 2 11 24496970-25082631 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039007, HPA046161 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Group enriched Group enriched 5 adrenal gland: 8.6;cerebral cortex: 33.0 prostate: 3.8 Group enriched 6 HaCaT: 9.2;HAP1: 5.4 +LHFPL3 LHFPL4 ENSG00000187416 Lipoma HMGIC fusion partner-like 3 7 104328656-104907232 Predicted membrane proteins Evidence at transcript level HPA069691 Approved Vesicles Tissue enriched Tissue enriched 10 cerebral cortex: 48.7 cervix, uterine: 4.6 Cell line enhanced SCLC-21H: 1.8;SH-SY5Y: 2.1;SK-BR-3: 1.3 +CHP1 CHP, p22, p24, Sid470p, SLC9A1BP ENSG00000187446 Calcineurin like EF-hand protein 1 15 41230839-41281890 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006616 Approved Approved Vesicles Renal cancer:2.79e-6 (favourable), Liver cancer:4.07e-6 (favourable), Endometrial cancer:9.63e-4 (favourable) Expressed in all Expressed in all colon: 110.9 Expressed in all +FPR3 FMLPY, FPRH1, FPRL2, RMLP-R-I ENSG00000187474 Formyl peptide receptor 3 19 51795163-51826189 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Testis cancer:9.13e-4 (unfavourable) Expressed in all Mixed lung: 41.2 Cell line enriched 9 HEL: 9.0 +HIST1H1T H1FT, H1t ENSG00000187475 Histone cluster 1 H1 family member t 6 26107419-26108136 Predicted intracellular proteins Evidence at protein level HPA065718, HPA068266 Enhanced Not detected Tissue enriched 8 testis: 1.4 appendix,breast,prostate: 0.1 Not detected +C11orf96 AG2 ENSG00000187479 Chromosome 11 open reading frame 96 11 43925342-43944338 Predicted intracellular proteins Evidence at protein level HPA038843 Uncertain Approved Nucleus
Focal adhesion sites
Cytosol Renal cancer:2.34e-5 (unfavourable) Expressed in all Mixed adrenal gland: 163.5 Cell line enriched 12 SH-SY5Y: 199.2 +KCNJ11 BIR, Kir6.2 ENSG00000187486 Potassium voltage-gated channel subfamily J member 11 11 17385859-17389331 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA048891 Approved Renal cancer:1.56e-4 (favourable) Mixed Tissue enhanced skeletal muscle: 32.7 cerebral cortex: 10.2 Cell line enhanced HEK 293: 12.0;MCF7: 8.2;SCLC-21H: 10.3 +CDHR4 CDH29, VLLR9392 ENSG00000187492 Cadherin related family member 4 3 49790732-49799835 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA076277 Enhanced Tissue enriched Tissue enriched 9 fallopian tube: 105.0 lung: 11.4 Cell line enhanced ASC TERT1: 1.0 +COL4A1 ENSG00000187498 Collagen type IV alpha 1 chain 13 110148963-110307149 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB001695, HPA054039 Approved Uncertain Nucleoplasm
Cytosol Renal cancer:1.30e-7 (unfavourable), Cervical cancer:4.67e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 1237.0 smooth muscle: 436.3 Cell line enhanced ASC diff: 355.1;EFO-21: 845.9 +PLEKHG7 FLJ46688 ENSG00000187510 Pleckstrin homology and RhoGEF domain containing G7 12 92721462-92772455 Predicted intracellular proteins Evidence at transcript level HPA060632 Uncertain Mixed Tissue enhanced epididymis: 3.6;fallopian tube: 4.3 cervix, uterine: 2.6 Cell line enhanced RPMI-8226: 1.1 +GJA4 CX37 ENSG00000187513 Gap junction protein alpha 4 1 34792998-34795747 Predicted membrane proteins, Transporters Evidence at protein level HPA047981 Approved Liver cancer:3.28e-4 (favourable), Renal cancer:7.44e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 89.3 fallopian tube: 48.2 Cell line enriched 8 EFO-21: 70.4 +PTMA TMSA ENSG00000187514 Prothymosin, alpha 2 231706895-231713541 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047183, HPA052651 Approved Enhanced Nucleus
Cytosol Renal cancer:1.99e-7 (unfavourable), Liver cancer:3.61e-4 (unfavourable), Cervical cancer:6.56e-4 (favourable) Expressed in all Expressed in all lymph node: 1620.2 Expressed in all +HYPM CXorf27, HIP17 ENSG00000187516 Huntingtin interacting protein M X 37990817-37991317 Predicted intracellular proteins Evidence at protein level HPA003356 Supported Not detected Tissue enriched 153 testis: 50.1 skin: 0.3 Not detected +HSPA14 HSP70-4, HSP70L1 ENSG00000187522 Heat shock protein family A (Hsp70) member 14 10 14838164-14871741 Predicted intracellular proteins Evidence at protein level HPA046180 Approved Liver cancer:3.70e-8 (unfavourable), Renal cancer:1.09e-5 (unfavourable), Head and neck cancer:5.73e-4 (favourable), Ovarian cancer:9.16e-4 (favourable) Expressed in all Expressed in all testis: 57.5 Expressed in all +ATP13A5 FLJ16025 ENSG00000187527 ATPase 13A5 3 193274790-193378843 Predicted membrane proteins Evidence at transcript level HPA031771, HPA031774 Uncertain Tissue enhanced Tissue enhanced breast: 17.7 salivary gland: 3.9 Cell line enhanced SK-BR-3: 1.2 +SIRT7 ENSG00000187531 Sirtuin 7 17 81911939-81921323 Predicted intracellular proteins Evidence at protein level CAB037261, HPA053669 Enhanced Supported Nucleoli fibrillar center
Vesicles Renal cancer:1.69e-7 (unfavourable), Liver cancer:1.97e-5 (unfavourable) Expressed in all Mixed esophagus: 21.6 Expressed in all +PRR27 C4orf40 ENSG00000187533 Proline rich 27 4 70133616-70176799 Predicted secreted proteins Evidence at protein level HPA036150, HPA036151 Enhanced Tissue enriched Tissue enriched 1077 salivary gland: 402.8 ovary: 0.3 Not detected +IFT140 gs114, KIAA0590, WDTC2 ENSG00000187535 Intraflagellar transport 140 16 1510427-1612110 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042197 Approved Expressed in all Mixed fallopian tube: 23.9 Mixed +POTEG A26C2, CT104.4, POTE-14, POTE14, POTE14alpha ENSG00000187537 POTE ankyrin domain family member G 14 19402486-19434341 Predicted intracellular proteins Evidence at transcript level HPA042822 Uncertain Tissue enhanced Tissue enhanced prostate: 3.5 testis: 0.7 Not detected +PRAMEF10 ENSG00000187545 PRAME family member 10 1 12892896-12898270 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 12 liver: 1.1 all non-specific tissues: 0.0 Not detected +AGMO FLJ16237, TMEM195 ENSG00000187546 Alkylglycerol monooxygenase 7 15200318-15562015 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA057900 Uncertain Vesicles Tissue enriched Tissue enhanced liver: 63.7 epididymis: 17.6 Cell line enhanced Karpas-707: 5.6;SCLC-21H: 3.8;WM-115: 15.2 +SBK2 SGK069 ENSG00000187550 SH3 domain binding kinase family member 2 19 55529733-55537089 Enzymes, Predicted membrane proteins Evidence at transcript level HPA030631 Uncertain Tissue enhanced Tissue enriched 30 heart muscle: 24.2 testis: 0.8 Group enriched 5 A549: 2.5;Hep G2: 1.4;MCF7: 2.2;NTERA-2: 5.5;RH-30: 4.9;U-2 OS: 3.1 +CYP26C1 ENSG00000187553 Cytochrome P450 family 26 subfamily C member 1 10 93060808-93069536 Disease related genes, Predicted membrane proteins Evidence at transcript level Not detected Not detected spleen: 0.2 Not detected +TLR5 FLJ10052, MGC126430, MGC126431, SLEB1, TIL3 ENSG00000187554 Toll like receptor 5 1 223109406-223143282 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009013 Approved Nucleus
Golgi apparatus
Cytosol Renal cancer:4.95e-4 (unfavourable) Mixed Mixed ovary: 25.2 Cell line enhanced A-431: 1.9;HaCaT: 3.3;T-47d: 2.2 +USP7 HAUSP ENSG00000187555 Ubiquitin specific peptidase 7 16 8892094-8964514 Enzymes, Predicted intracellular proteins Evidence at protein level CAB008108, HPA015641 Approved Renal cancer:8.56e-5 (favourable) Expressed in all Expressed in all testis: 109.1 Expressed in all +NANOS3 NANOS1L, NOS3, ZC2HC12C ENSG00000187556 Nanos C2HC-type zinc finger 3 19 13862063-13880757 Predicted intracellular proteins Evidence at protein level HPA062989 Enhanced Tissue enriched Tissue enriched 6 testis: 7.0 cerebral cortex: 1.1 Not detected +FOXD4L3 FOXD6 ENSG00000187559 Forkhead box D4-like 3 9 68302867-68304905 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA012836 Uncertain Approved Nucleus Not detected Not detected spleen: 0.3 Not detected +NHLRC1 bA204B7.2, EPM2B, malin ENSG00000187566 NHL repeat containing E3 ubiquitin protein ligase 1 6 18120440-18122687 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA066030 Uncertain Vesicles Urothelial cancer:5.30e-4 (favourable), Endometrial cancer:9.01e-4 (unfavourable) Expressed in all Mixed skin: 4.5 Cell line enhanced EFO-21: 6.4;SCLC-21H: 7.2 +DPPA3 Stella ENSG00000187569 Developmental pluripotency associated 3 12 7711454-7717559 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enhanced testis: 1.3 lung: 0.6 Group enriched 248 BEWO: 334.2;NTERA-2: 146.4 +COX8C COX8-3 ENSG00000187581 Cytochrome c oxidase subunit 8C 14 93347191-93348356 Predicted membrane proteins, Transporters Evidence at transcript level HPA003127 Approved Group enriched Tissue enriched 51 testis: 29.7 fallopian tube: 0.5 Cell line enriched 7 U-937: 11.3 +PLEKHN1 DKFZP434H2010 ENSG00000187583 Pleckstrin homology domain containing N1 1 966497-975865 Predicted intracellular proteins Evidence at protein level HPA031742 Uncertain Approved Nuclear speckles Renal cancer:4.97e-5 (unfavourable) Mixed Group enriched 11 esophagus: 16.9;skin: 44.0 urinary bladder: 2.7 Cell line enhanced HaCaT: 22.0 +ZNF385C ENSG00000187595 Zinc finger protein 385C 17 42025576-42098479 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced testis: 8.9 ovary: 2.0 Cell line enhanced HDLM-2: 1.7;MOLT-4: 2.6;SCLC-21H: 3.0 +TMEM247 ENSG00000187600 Transmembrane protein 247 2 46429190-46484425 Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 26 testis: 35.7 placenta: 1.3 Cell line enriched 13 U-266/84: 1.5 +MAGEH1 APR1 ENSG00000187601 MAGE family member H1 X 55452105-55453566 Predicted membrane proteins Evidence at protein level HPA011324 Uncertain Approved Nucleoli Endometrial cancer:1.37e-4 (unfavourable), Pancreatic cancer:2.60e-4 (favourable) Expressed in all Tissue enriched 5 epididymis: 616.6 cerebral cortex: 115.7 Mixed +TET3 hCG_40738, MGC22014 ENSG00000187605 Tet methylcytosine dioxygenase 3 2 73986404-74108176 Enzymes, Predicted intracellular proteins Evidence at protein level HPA050845 Approved Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:3.58e-5 (unfavourable) Expressed in all Mixed skin: 17.9 Mixed +ZNF286A KIAA1874, ZNF286 ENSG00000187607 Zinc finger protein 286A 17 15699577-15720787 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021594 Approved Nucleoli Mixed Mixed ovary: 21.8 Mixed +ISG15 G1P2, IFI15, UCRP ENSG00000187608 ISG15 ubiquitin-like modifier 1 1001138-1014541 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA004627 Approved Renal cancer:5.11e-10 (unfavourable) Expressed in all Expressed in all salivary gland: 112.8 Expressed in all +EXD3 FLJ20433, LOC54932, mut-7 ENSG00000187609 Exonuclease 3'-5' domain containing 3 9 137306896-137423262 Predicted intracellular proteins Evidence at protein level HPA047395 Approved Approved Actin filaments
Focal adhesion sites Endometrial cancer:4.30e-4 (favourable) Expressed in all Mixed small intestine,spleen: 10.0 Mixed +OR5W2 OR5W2P, OR5W3P ENSG00000187612 Olfactory receptor family 5 subfamily W member 2 11 55913650-55914582 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +TMEM8C TMEM226 ENSG00000187616 Transmembrane protein 8C 9 133514586-133528612 Predicted membrane proteins, Transporters Evidence at transcript level HPA051846, HPA055785 Uncertain Not detected Not detected cerebral cortex,epididymis: 0.5 Group enriched 29 HSkMC: 11.3;RH-30: 6.9 +C17orf97 LIAT1, LOC400566 ENSG00000187624 Chromosome 17 open reading frame 97 17 410327-431062 Predicted intracellular proteins Evidence at protein level HPA023583 Approved Approved Nucleoli
Cytosol Expressed in all Tissue enhanced testis: 28.4 fallopian tube: 10.8 Cell line enhanced U-2197: 8.4 +ZKSCAN4 FLJ32136, P1P373C6, p373c6.1, ZNF307, ZNF427, ZSCAN36 ENSG00000187626 Zinc finger with KRAB and SCAN domains 4 6 28244623-28252224 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009637 Approved Approved Nucleoplasm
Cytosol Liver cancer:1.90e-6 (unfavourable), Lung cancer:5.04e-4 (favourable) Expressed in all Mixed testis: 18.3 Expressed in all +RGPD1 RGP1 ENSG00000187627 RANBP2-like and GRIP domain containing 1 2 86907953-87013981 Predicted intracellular proteins Evidence at transcript level HPA049497, HPA051675, HPA067564 Uncertain Approved Nuclear membrane
Vesicles Not detected Group enriched 12 cervix, uterine: 11.8;placenta: 9.0;testis: 24.5 parathyroid gland: 1.2 Cell line enhanced BEWO: 6.0;MOLT-4: 8.6;NTERA-2: 3.1 +DHRS4L2 SDR25C3 ENSG00000187630 Dehydrogenase/reductase 4 like 2 14 23969874-24006408 Predicted intracellular proteins Evidence at protein level HPA023972 Uncertain Uncertain Nuclear membrane
Vesicles Ovarian cancer:3.21e-4 (favourable) Expressed in all Expressed in all kidney: 123.6 Mixed +SAMD11 MGC45873 ENSG00000187634 Sterile alpha motif domain containing 11 1 923928-944581 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030110 Approved Nucleoplasm
Vesicles Renal cancer:3.35e-5 (unfavourable) Expressed in all Tissue enhanced seminal vesicle: 27.6 fallopian tube: 20.4 Cell line enhanced HEK 293: 98.5;HeLa: 80.1;SCLC-21H: 89.8 +PERM1 C1orf170, MGC13275, Perm1, RP11-54O7.8 ENSG00000187642 PPARGC1 and ESRR induced regulator, muscle 1 1 975204-982093 Predicted intracellular proteins Evidence at protein level HPA031711, HPA031712 Enhanced Renal cancer:1.95e-4 (unfavourable) Mixed Group enriched 15 heart muscle: 20.7;skeletal muscle: 68.1 esophagus: 3.0 Cell line enhanced HaCaT: 1.3;SK-BR-3: 1.2 +VMAC ENSG00000187650 Vimentin-type intermediate filament associated coiled-coil protein 19 5904858-5910853 Predicted intracellular proteins Evidence at protein level Endometrial cancer:5.67e-6 (favourable), Urothelial cancer:7.24e-4 (favourable), Head and neck cancer:8.20e-4 (favourable) Expressed in all Mixed prostate: 7.9 Cell line enhanced U-266/70: 12.2 +C5orf52 ENSG00000187658 Chromosome 5 open reading frame 52 5 157671553-157680143 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enriched 21 testis: 38.7 colon: 1.8 Not detected +HAPLN4 BRAL2, KIAA1926 ENSG00000187664 Hyaluronan and proteoglycan link protein 4 19 19255641-19262796 Predicted secreted proteins Evidence at protein level HPA055856 Approved Not detected Group enriched 7 cerebral cortex: 8.4;duodenum: 15.3;small intestine: 21.2 cervix, uterine: 2.1 Cell line enhanced NB-4: 2.6;NTERA-2: 10.4;SCLC-21H: 2.6 +ERC2 CAST, CAST1, ELKSL, KIAA0378, SPBC110, Spc110 ENSG00000187672 ELKS/RAB6-interacting/CAST family member 2 3 55508308-56468363 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA073739 Enhanced Mixed Tissue enriched 16 cerebral cortex: 24.6 seminal vesicle: 1.5 Cell line enhanced HAP1: 2.7;Karpas-707: 6.2;SH-SY5Y: 2.2;U-266/70: 4.6 +B3GLCT B3GALTL, B3Glc-T, B3GTL ENSG00000187676 Beta 3-glucosyltransferase 13 31199936-31332276 Disease related genes, Predicted secreted proteins Evidence at protein level Expressed in all Mixed endometrium: 21.1 Cell line enhanced HDLM-2: 54.9 +SPRY4 ENSG00000187678 Sprouty RTK signaling antagonist 4 5 142310427-142326455 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB008086, HPA055471, HPA072661 Enhanced Approved Golgi apparatus
Cytosol Renal cancer:2.20e-4 (unfavourable), Cervical cancer:7.12e-4 (unfavourable) Expressed in all Mixed adipose tissue: 26.9 Cell line enhanced AN3-CA: 111.1;WM-115: 158.0 +ERAS HRAS2, HRASP ENSG00000187682 ES cell expressed Ras X 48826513-48830138 Predicted intracellular proteins Evidence at transcript level Mixed Not detected cerebral cortex: 0.6 Not detected +TRPV2 VRL, VRL-1, VRL1 ENSG00000187688 Transient receptor potential cation channel subfamily V member 2 17 16415542-16437003 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA044993 Uncertain Supported Plasma membrane Renal cancer:1.19e-6 (unfavourable), Testis cancer:5.53e-4 (unfavourable) Tissue enriched Mixed lung: 44.1 Cell line enhanced fHDF/TERT166: 83.8;HMC-1: 77.5;SK-MEL-30: 73.0;TIME: 68.5 +AMTN RSTI689, UNQ689 ENSG00000187689 Amelotin 4 70518540-70532742 Predicted secreted proteins Evidence at protein level HPA036136, HPA036137 Uncertain Group enriched Tissue enhanced stomach: 6.9;tonsil: 24.9 prostate: 3.3 Cell line enhanced hTERT-HME1: 3.4;MCF7: 2.6 +CXorf67 ENSG00000187690 Chromosome X open reading frame 67 X 51406915-51408843 Predicted intracellular proteins Evidence at protein level HPA004003, HPA006128 Enhanced Enhanced Nucleoplasm Tissue enriched Group enriched 21 placenta: 1.3;testis: 4.7 cerebral cortex,epididymis,ovary,prostate,spleen: 0.1 Cell line enriched 63 U-2 OS: 34.0 +RP11-723O4.6 ENSG00000187695 Uncharacterized protein FLJ43738 3 128909874-128971330 Predicted intracellular proteins Evidence at transcript level Mixed Group enriched 5 fallopian tube: 10.7;skin: 6.8;testis: 20.3 lung: 2.4 Cell line enhanced HAP1: 4.6;HL-60: 4.8 +C2orf88 MGC13057, smAKAP ENSG00000187699 Chromosome 2 open reading frame 88 2 189879609-190203484 Predicted intracellular proteins Evidence at protein level HPA049549 Approved Endometrial cancer:4.97e-4 (favourable), Renal cancer:7.79e-4 (favourable), Melanoma:9.39e-4 (unfavourable) Tissue enhanced Expressed in all testis: 92.3 Group enriched 6 HEL: 97.1;K-562: 82.2;RT4: 46.8 +OR2T27 ENSG00000187701 Olfactory receptor family 2 subfamily T member 27 1 248649931-248650884 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +TMEM203 HBEBP1, MGC14327 ENSG00000187713 Transmembrane protein 203 9 137204082-137205638 Predicted membrane proteins, Transporters Evidence at protein level Pancreatic cancer:4.78e-6 (favourable), Renal cancer:1.50e-5 (favourable) Expressed in all Expressed in all thyroid gland: 39.9 Expressed in all +SLC18A3 VACHT ENSG00000187714 Solute carrier family 18 member A3 10 49610301-49612720 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB037102, CAB079011 Uncertain Supported Mixed Not detected placenta: 0.6 Group enriched 6 SCLC-21H: 2.0;SH-SY5Y: 7.6 +KBTBD12 FLJ46299, KLHDC6 ENSG00000187715 Kelch repeat and BTB domain containing 12 3 127915232-127987671 Predicted intracellular proteins Evidence at protein level Mixed Group enriched 9 heart muscle: 9.2;skeletal muscle: 20.3 stomach: 1.5 Not detected +THSD4 ADAMTSL6, FLJ13710, FVSY9334, PRO34005 ENSG00000187720 Thrombospondin type 1 domain containing 4 15 71096952-71783383 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026845 Approved Nucleus
Nucleoli Mixed Tissue enhanced cervix, uterine: 160.5 fallopian tube: 59.6 Cell line enhanced BJ hTERT+: 43.1;TIME: 54.2 +DNAJB13 RSPH16A, TSARG6 ENSG00000187726 DnaJ heat shock protein family (Hsp40) member B13 11 73950319-73970366 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA052465, HPA061330 Enhanced Approved Plasma membrane Renal cancer:2.10e-6 (unfavourable) Tissue enhanced Group enriched 7 fallopian tube: 76.0;testis: 19.1 cervix, uterine,epididymis: 6.4 Cell line enhanced RPTEC TERT1: 3.3 +GABRD ENSG00000187730 Gamma-aminobutyric acid type A receptor delta subunit 1 2019298-2030758 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA044371 Enhanced Uncertain Golgi apparatus
Vesicles Renal cancer:4.12e-8 (unfavourable) Expressed in all Tissue enriched 12 cerebral cortex: 34.0 testis: 2.7 Cell line enhanced EFO-21: 1.3;MCF7: 3.1;NB-4: 1.6;SH-SY5Y: 1.6 +AMY1C AMY1 ENSG00000187733 Amylase, alpha 1C (salivary) 1 103750406-103758690 Enzymes, Predicted secreted proteins Evidence at protein level HPA045394, HPA045399, HPA046980 Supported Not detected Tissue enhanced cervix, uterine: 33.0;salivary gland: 101.8 pancreas: 26.4 Not detected +TCEA1 GTF2S, SII, TCEA, TF2S, TFIIS ENSG00000187735 Transcription elongation factor A1 8 53966552-54022529 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043786 Approved Supported Nucleus
Nucleoli Renal cancer:3.75e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 199.9 Expressed in all +NHEJ1 Cernunnos, FLJ12610, XLF ENSG00000187736 Non-homologous end joining factor 1 2 219075317-219160865 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB012334, HPA043869 Approved Supported Nucleus
Nucleoli fibrillar center Mixed Expressed in all testis: 44.0 Expressed in all +FANCA FA-H, FAA, FACA, FAH, FANCH ENSG00000187741 Fanconi anemia complementation group A 16 89737549-89816657 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA063236 Supported Nucleus Mixed Mixed testis: 19.5 Expressed in all +SECISBP2 ENSG00000187742 SECIS binding protein 2 9 89318506-89359662 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044314, HPA054905 Approved Supported Nucleoplasm Renal cancer:8.98e-9 (favourable) Expressed in all Expressed in all testis: 127.0 Expressed in all +OR52B6 ENSG00000187747 Olfactory receptor family 52 subfamily B member 6 11 5580877-5581884 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +C9orf153 bA507D14.1 ENSG00000187753 Chromosome 9 open reading frame 153 9 86220265-86259657 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 29 testis: 53.7 bone marrow: 1.8 Mixed +SSX7 ENSG00000187754 SSX family member 7 X 52644090-52654900 Predicted intracellular proteins Evidence at transcript level HPA045683 Uncertain Approved Nucleus
Nucleoli Not detected Not detected skin: 0.4 Cell line enhanced HMC-1: 2.8;RT4: 1.4 +ADH1A ADH1 ENSG00000187758 Alcohol dehydrogenase 1A (class I), alpha polypeptide 4 99276367-99291028 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009562, HPA047814, HPA060902 Enhanced Approved Plasma membrane
Cytosol Liver cancer:2.38e-4 (favourable) Tissue enriched Tissue enriched 135 liver: 1367.7 gallbladder: 10.1 Cell line enhanced ASC diff: 3.7 +SEMA4D C9orf164, CD100, coll-4, FLJ39737, SEMAJ ENSG00000187764 Semaphorin 4D 9 89360787-89498130 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015662, HPA023277 Approved Supported Endoplasmic reticulum
Vesicles Urothelial cancer:4.06e-5 (favourable), Cervical cancer:4.17e-4 (favourable) Expressed in all Expressed in all lymph node: 72.4 Cell line enhanced HDLM-2: 124.4;HMC-1: 86.7;MOLT-4: 98.7 +KRTAP10-8 KAP10.8, KRTAP18-8, KRTAP18.8 ENSG00000187766 Keratin associated protein 10-8 21 44612079-44612954 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +LIN28B CSDD2, FLJ16517 ENSG00000187772 Lin-28 homolog B 6 104936616-105083332 Predicted intracellular proteins Evidence at protein level HPA036630, HPA061745 Enhanced Supported Nucleus
Nucleoli
Cytosol Tissue enriched Tissue enriched 12 placenta: 93.5 testis: 7.7 Cell line enhanced BEWO: 241.5;K-562: 76.8 +FAM69C C18orf51 ENSG00000187773 Family with sequence similarity 69 member C 18 74434099-74457944 Predicted intracellular proteins Evidence at protein level HPA048928 Enhanced Group enriched Tissue enhanced cerebral cortex: 28.8;testis: 8.4 skin: 4.9 Cell line enriched 7 SK-MEL-30: 4.2 +DNAH17 DNAHL1, DNEL2, FLJ40457 ENSG00000187775 Dynein axonemal heavy chain 17 17 78423697-78577394 Predicted intracellular proteins Evidence at protein level HPA024354, HPA076261 Enhanced Approved Nucleoplasm
Plasma membrane Tissue enhanced Tissue enriched 21 testis: 10.3 skin: 0.4 Group enriched 5 HeLa: 3.2;MOLT-4: 1.9 +MCRS1 ICP22BP, INO80Q, MCRS2, MSP58, P78 ENSG00000187778 Microspherule protein 1 12 49556544-49568153 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039057 Supported Supported Nucleoplasm Liver cancer:2.30e-4 (unfavourable), Renal cancer:2.70e-4 (favourable) Expressed in all Expressed in all thyroid gland: 55.0 Expressed in all +TMEM72 bA285G1.3, C10orf127, KSP37 ENSG00000187783 Transmembrane protein 72 10 44911200-44937002 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039894, HPA062907 Enhanced Renal cancer:1.01e-4 (favourable) Tissue enriched Tissue enriched 7 kidney: 54.3 rectum: 7.8 Group enriched 105 RPMI-8226: 24.8;U-937: 17.4 +FANCM FAAP250, KIAA1596 ENSG00000187790 Fanconi anemia complementation group M 14 45135940-45200890 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055144 Supported Nucleoplasm Mixed Tissue enhanced testis: 14.0 endometrium: 4.3 Mixed +FAM205C FAM205CP ENSG00000187791 Family with sequence similarity 205 member C 9 34889064-34895778 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 61 testis: 46.8 kidney: 0.7 Cell line enriched 84 THP-1: 9.8 +ZNF70 Cos17, MGC48959 ENSG00000187792 Zinc finger protein 70 22 23738678-23751092 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018821 Uncertain Supported Cytosol Mixed Mixed ovary: 4.9 Mixed +CARD9 ENSG00000187796 Caspase recruitment domain family member 9 9 136361903-136373681 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA059502 Enhanced Mixed Tissue enhanced bone marrow: 7.1;spleen: 8.2 appendix: 5.7 Cell line enhanced HMC-1: 49.3;NB-4: 30.7;THP-1: 30.1 +PEAR1 FLJ00193, JEDI, MEGF12 ENSG00000187800 Platelet endothelial aggregation receptor 1 1 156893698-156916434 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035217 Approved Approved Nucleoplasm
Cell Junctions
Centrosome Renal cancer:4.31e-4 (unfavourable) Expressed in all Mixed placenta: 16.9 Cell line enhanced HBEC3-KT: 21.4;HUVEC TERT2: 43.6;TIME: 69.3 +ZFP69B FLJ34293, ZKSCAN23B, ZNF643, ZSCAN54B ENSG00000187801 ZFP69 zinc finger protein B 1 40450102-40463718 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044289 Uncertain Approved Nucleus
Cytosol Mixed Mixed cerebral cortex: 3.7 Mixed +TMEM202 FLJ27523 ENSG00000187806 Transmembrane protein 202 15 72398273-72408029 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Tissue enriched Tissue enriched 230 testis: 23.0 all non-specific tissues: 0.0 Not detected +SOWAHD ANKRD58 ENSG00000187808 Sosondowah ankyrin repeat domain family member D X 119758613-119760164 Predicted intracellular proteins Evidence at protein level HPA065955 Uncertain Tissue enriched Tissue enhanced spleen: 5.0 testis: 3.6 Cell line enhanced BEWO: 4.3;THP-1: 5.8;U-937: 6.0 +ZFP69 FLJ16030, ZFP69A, ZKSCAN23A, ZNF642, ZSCAN54A ENSG00000187815 ZFP69 zinc finger protein 1 40477215-40496343 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027808, HPA054942 Uncertain Approved Nucleus Renal cancer:5.00e-6 (unfavourable), Head and neck cancer:9.31e-4 (favourable) Expressed in all Mixed testis: 6.7 Cell line enhanced THP-1: 39.0 +HELT bHLHb44, HCM1228, HESL, MEGANE, Mgn ENSG00000187821 Helt bHLH transcription factor 4 185018841-185020804 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA036188, HPA036189 Uncertain Not detected Not detected lung: 0.5 Cell line enhanced HAP1: 1.4 +ZCCHC16 FLJ46608, Mar4, Mart4 ENSG00000187823 Zinc finger CCHC-type containing 16 X 112454500-112457112 Predicted intracellular proteins Evidence at transcript level HPA003272 Uncertain Approved Nucleus
Plasma membrane
Cytosol Group enriched Not detected kidney: 0.8 Not detected +TMEM220 ENSG00000187824 Transmembrane protein 220 17 10699015-10730316 Predicted membrane proteins Evidence at protein level HPA047680 Uncertain Nucleoplasm Liver cancer:2.23e-5 (favourable), Pancreatic cancer:1.72e-4 (favourable), Glioma:9.39e-4 (unfavourable) Expressed in all Expressed in all liver: 53.3 Mixed +C2orf78 COG5373, FLJ43987, hCG1989538 ENSG00000187833 Chromosome 2 open reading frame 78 2 73784189-73817147 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 142 testis: 14.2 all non-specific tissues: 0.0 Not detected +HIST1H1C H1.2, H1c, H1F2, H1s-1 ENSG00000187837 Histone cluster 1 H1 family member c 6 26055787-26056428 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011507, HPA055907 Supported Supported Nucleus
Nucleoli Urothelial cancer:8.06e-5 (favourable), Pancreatic cancer:1.12e-4 (unfavourable), Renal cancer:1.56e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 185.2 Cell line enhanced SiHa: 391.5;U-2 OS: 735.9;U-266/70: 600.9;U-266/84: 562.5 +PLSCR3 ENSG00000187838 Phospholipid scramblase 3 17 7389727-7394843 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048387, HPA068609 Supported Supported Mitochondria Mixed Mixed smooth muscle: 19.5 Mixed +EIF4EBP1 4E-BP1, PHAS-I ENSG00000187840 Eukaryotic translation initiation factor 4E binding protein 1 8 38030341-38060365 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB005032, CAB005039, HPA023501 Supported Supported Nucleoplasm
Cytosol Renal cancer:0.00e+0 (unfavourable), Endometrial cancer:8.86e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 30.5 Expressed in all +P2RX2 DFNA41, P2X2 ENSG00000187848 Purinergic receptor P2X 2 12 132618780-132622386 Disease related genes, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced epididymis: 26.6;seminal vesicle: 12.7 prostate: 9.7 Cell line enhanced MCF7: 3.9;T-47d: 10.5 +ASCL4 bHLHa44, HASH4 ENSG00000187855 Achaete-scute family bHLH transcription factor 4 12 107774385-107776644 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036116 Uncertain Tissue enhanced Not detected parathyroid gland: 0.7 Not detected +OR6C75 ENSG00000187857 Olfactory receptor family 6 subfamily C member 75 12 55365111-55366049 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +CCDC157 ENSG00000187860 Coiled-coil domain containing 157 22 30356635-30378658 Predicted intracellular proteins Evidence at protein level HPA042943 Uncertain Mixed Group enriched 5 fallopian tube: 12.0;testis: 28.4 thyroid gland: 3.9 Mixed +TTC24 ENSG00000187862 Tetratricopeptide repeat domain 24 1 156579727-156586770 Predicted intracellular proteins Evidence at protein level HPA029799 Approved Nucleoplasm Not detected Tissue enhanced lymph node: 6.4;spleen: 3.8;tonsil: 4.2 appendix: 2.4 Cell line enhanced MOLT-4: 2.5;REH: 10.7;U-698: 1.5 +FAM122A C9orf42, MGC17347 ENSG00000187866 Family with sequence similarity 122A 9 68780034-68784608 Predicted intracellular proteins Evidence at protein level HPA056646 Approved Approved Nucleoplasm
Nuclear bodies Renal cancer:1.34e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 21.3 Expressed in all +PALM3 ENSG00000187867 Paralemmin 3 19 14053365-14059159 Predicted intracellular proteins Evidence at protein level HPA052794, HPA056119 Enhanced Approved Nucleoplasm
Nuclear bodies
Plasma membrane Endometrial cancer:7.87e-4 (unfavourable) Mixed Mixed kidney: 15.7 Cell line enhanced AN3-CA: 35.4;CACO-2: 34.5;HAP1: 35.4;NTERA-2: 24.5 +GFRAL bA360D14.1, C6orf144, GRAL, UNQ9356 ENSG00000187871 GDNF family receptor alpha like 6 55327469-55402493 Predicted membrane proteins Evidence at protein level HPA047372 Uncertain Not detected Not detected testis: 0.2 Not detected +C1orf168 FLJ43208, RP4-758N20.2 ENSG00000187889 Chromosome 1 open reading frame 168 1 56718804-56819696 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced fallopian tube: 21.4;liver: 8.6 cervix, uterine: 5.0 Cell line enriched 22 T-47d: 4.8 +SHISA7 ENSG00000187902 Shisa family member 7 19 55428740-55442863 Predicted membrane proteins Evidence at protein level HPA058935 Uncertain Tissue enriched Tissue enriched 13 cerebral cortex: 18.2 testis: 1.4 Cell line enhanced HEL: 2.7;HMC-1: 2.7;THP-1: 1.1 +LRRC74B ENSG00000187905 Leucine rich repeat containing 74B 22 21045960-21064168 Predicted intracellular proteins Evidence at transcript level HPA049947 Uncertain Not detected Tissue enhanced fallopian tube: 6.0;testis: 1.9 lung: 0.8 Not detected +DMBT1 GP340, muclin, SALSA ENSG00000187908 Deleted in malignant brain tumors 1 10 122560665-122643736 Disease related genes, Predicted secreted proteins Evidence at protein level HPA040778 Enhanced Approved Microtubule organizing center Endometrial cancer:1.43e-4 (favourable) Group enriched Tissue enhanced duodenum: 816.7;small intestine: 277.6 salivary gland: 136.1 Cell line enhanced hTERT-HME1: 3.5;LHCN-M2: 7.8;RH-30: 20.9 +CLEC17A FLJ45910 ENSG00000187912 C-type lectin domain family 17 member A 19 14583084-14611157 Predicted membrane proteins Evidence at protein level Mixed Group enriched 10 appendix: 16.6;lymph node: 30.4;spleen: 19.2;tonsil: 28.4 urinary bladder: 2.3 Group enriched 11 Daudi: 6.8;U-698: 12.0 +OR51I2 ENSG00000187918 Olfactory receptor family 51 subfamily I member 2 11 5453489-5454427 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +LCN10 ENSG00000187922 Lipocalin 10 9 136738167-136743356 Predicted secreted proteins Evidence at protein level HPA055919 Approved Tissue enriched Tissue enriched 6 epididymis: 18.9 endometrium: 3.3 Not detected +LDLRAD2 ENSG00000187942 Low density lipoprotein receptor class A domain containing 2 1 21812265-21825221 Predicted secreted proteins Evidence at transcript level HPA030478 Approved Mixed Mixed adipose tissue: 2.1 Cell line enhanced REH: 1.1;TIME: 1.8 +C2orf66 UNQ6411 ENSG00000187944 Chromosome 2 open reading frame 66 2 196805002-196810276 Predicted secreted proteins Evidence at transcript level HPA020869 Uncertain Mixed Tissue enhanced adipose tissue: 2.8;adrenal gland: 1.7;testis: 1.7 skin: 1.1 Cell line enhanced HEL: 4.0;RT4: 1.3;TIME: 1.5 +OVCH1 OVCH ENSG00000187950 Ovochymase 1 12 29412474-29497686 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA040253 Uncertain Not detected Group enriched 5 lung: 6.8;testis: 4.3;thyroid gland: 1.7 spleen: 0.8 Group enriched 6 Daudi: 3.9;HEL: 1.0 +ARHGAP11B B'-T, FAM7B1 ENSG00000187951 Rho GTPase activating protein 11B 15 30624494-30772993 Predicted intracellular proteins Evidence at protein level HPA064479 Uncertain Approved Vesicles Mixed Tissue enhanced bone marrow: 2.0 lymph node,testis: 1.1 Mixed +CYHR1 CHRP, KIAA0496, MGC13010 ENSG00000187954 Cysteine and histidine rich 1 8 144449582-144465677 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA053653, HPA059543 Approved Enhanced Nucleoplasm Colorectal cancer:1.05e-4 (unfavourable), Liver cancer:3.90e-4 (unfavourable) Expressed in all Expressed in all testis: 51.4 Expressed in all +COL14A1 UND ENSG00000187955 Collagen type XIV alpha 1 chain 8 120059780-120372036 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023781 Uncertain Approved Vesicles Renal cancer:5.79e-5 (unfavourable), Urothelial cancer:1.01e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 278.5 gallbladder: 207.5 Group enriched 7 ASC TERT1: 28.1;RH-30: 106.3 +DNER bet, UNQ26 ENSG00000187957 Delta/notch like EGF repeat containing 2 229357629-229714558 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA017320 Approved Liver cancer:1.05e-4 (unfavourable), Renal cancer:3.42e-4 (unfavourable) Tissue enriched Group enriched 7 adrenal gland: 74.6;cerebral cortex: 176.0 salivary gland: 17.3 Cell line enhanced hTERT-HME1: 115.0;U-138 MG: 248.6;U-87 MG: 146.3 +CPSF4L ENSG00000187959 Cleavage and polyadenylation specific factor 4 like 17 73248449-73262352 Predicted intracellular proteins Evidence at transcript level HPA044047 Uncertain Not detected Not detected testis: 0.9 Cell line enriched 7 Hep G2: 2.0 +KLHL17 ENSG00000187961 Kelch like family member 17 1 960587-965715 Predicted intracellular proteins Evidence at protein level HPA031251 Approved Approved Nucleoplasm
Nuclear bodies Liver cancer:1.89e-6 (unfavourable), Renal cancer:2.70e-6 (unfavourable), Cervical cancer:4.22e-4 (unfavourable) Expressed in all Mixed skin: 9.7 Expressed in all +ZCCHC13 4930513O09RIK, Cnbp2, ZNF9L ENSG00000187969 Zinc finger CCHC-type containing 13 X 74304190-74305031 Predicted intracellular proteins Evidence at protein level HPA003382 Enhanced Not detected Tissue enriched 234 testis: 23.3 all non-specific tissues: 0.0 Not detected +PLA2G2C ENSG00000187980 Phospholipase A2 group IIC 1 20161253-20177424 Predicted secreted proteins, RAS pathway related proteins Evidence at transcript level Not detected Tissue enhanced esophagus: 1.2 testis: 0.6 Cell line enhanced HL-60: 1.2;U-698: 1.2;U-937: 1.3 +ZSCAN23 dJ29K1.3.1, ZNF390, ZNF453 ENSG00000187987 Zinc finger and SCAN domain containing 23 6 28431930-28443502 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035959, HPA035960 Uncertain Not detected Mixed parathyroid gland: 2.1 Cell line enhanced SCLC-21H: 2.1 +RINL FLJ45909 ENSG00000187994 Ras and Rab interactor like 19 38867834-38878279 Predicted intracellular proteins Evidence at protein level HPA042083, HPA042103 Uncertain Approved Nucleoplasm
Vesicles Cervical cancer:6.49e-5 (favourable), Head and neck cancer:1.64e-4 (favourable) Expressed in all Mixed lymph node: 13.9 Cell line enhanced HMC-1: 20.0;Karpas-707: 19.3 +C17orf99 GLPG464, UNQ464 ENSG00000187997 Chromosome 17 open reading frame 99 17 78146353-78166177 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029655 Uncertain Not detected Tissue enriched 6 bone marrow: 5.5 fallopian tube,lymph node: 0.9 Group enriched 14 HaCaT: 3.1;HMC-1: 6.2;K-562: 3.8 +OR7D2 FLJ38149, HTPCRH03, OR19-4 ENSG00000188000 Olfactory receptor family 7 subfamily D member 2 19 9185594-9188817 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Mixed testis: 1.8 Cell line enhanced HEL: 1.6 +TPRG1 FAM79B, FLJ41238, FLJ43694 ENSG00000188001 Tumor protein p63 regulated 1 3 188947214-189325304 Predicted intracellular proteins Evidence at protein level HPA044751, HPA060187 Uncertain Supported Nucleoplasm Breast cancer:5.43e-4 (favourable) Tissue enhanced Tissue enhanced esophagus: 49.1 breast: 28.4 Cell line enhanced HDLM-2: 8.9;Karpas-707: 3.3;T-47d: 3.9;U-266/70: 3.5 +C1orf204 FLJ39187 ENSG00000188004 Chromosome 1 open reading frame 204 1 159834474-159855347 Predicted intracellular proteins Evidence at transcript level HPA045602, HPA051028 Approved Approved Nucleoplasm Mixed Mixed ovary,parathyroid gland: 8.3 Mixed +MORN2 MOPT ENSG00000188010 MORN repeat containing 2 2 38875962-38929072 Predicted intracellular proteins Evidence at protein level HPA057815 Uncertain Approved Nucleoplasm Expressed in all Expressed in all testis: 265.7 Expressed in all +RTP5 C2orf85, CXXC11, FLJ33590, Z3CXXC5 ENSG00000188011 Receptor transporter protein 5 (putative) 2 241869600-241873823 Predicted membrane proteins Evidence at protein level HPA050902 Approved Tissue enriched Tissue enriched 9 cerebral cortex: 5.3 lymph node: 0.5 Group enriched 21 MOLT-4: 1.1;SCLC-21H: 3.0 +S100A3 S100E ENSG00000188015 S100 calcium binding protein A3 1 153547329-153549372 Predicted intracellular proteins Evidence at protein level HPA042674, HPA056140 Approved Enhanced Nucleoli
Cytosol Renal cancer:1.61e-6 (unfavourable) Expressed in all Tissue enhanced lung: 19.9;skin: 17.3 esophagus: 7.5 Cell line enhanced A549: 71.3;U-2197: 41.8 +UBQLN2 Chap1, CHAP1/DSK2, Dsk2, LIC-2, N4BP4, PLIC-2, PLIC2, RIHFB2157 ENSG00000188021 Ubiquilin 2 X 56563639-56567868 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006431, CAB013481 Enhanced Enhanced Plasma membrane
Cytosol Liver cancer:2.29e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 53.7 Expressed in all +RILPL1 FLJ39378 ENSG00000188026 Rab interacting lysosomal protein like 1 12 123470054-123533718 Predicted intracellular proteins Evidence at protein level HPA041314 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Mixed heart muscle: 34.5 Mixed +C19orf67 ENSG00000188032 Chromosome 19 open reading frame 67 19 14081619-14085875 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 11 testis: 5.6 stomach,thyroid gland: 0.4 Not detected +ZNF490 KIAA1198 ENSG00000188033 Zinc finger protein 490 19 12577961-12640098 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005576 Uncertain Mixed Mixed thyroid gland: 2.8 Mixed +CLCN1 ClC-1, CLC1 ENSG00000188037 Chloride voltage-gated channel 1 7 143316126-143352083 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Mixed Tissue enriched 17 skeletal muscle: 22.9 testis: 1.3 Cell line enhanced HSkMC: 1.1;PC-3: 1.0 +NRN1L MRCC2446, UNQ2446 ENSG00000188038 Neuritin 1 like 16 67884805-67888855 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA041761 Uncertain Not detected Mixed skin: 3.3 Cell line enriched 5 BEWO: 31.0 +NWD1 ENSG00000188039 NACHT and WD repeat domain containing 1 19 16719976-16817963 Predicted intracellular proteins Evidence at protein level Endometrial cancer:2.55e-4 (favourable) Tissue enriched Group enriched 7 cerebral cortex: 1.9;fallopian tube: 7.7;prostate: 5.8;seminal vesicle: 1.6 lung: 0.6 Group enriched 7 MCF7: 1.0;U-937: 2.3 +ARL4C ARL7, LAK ENSG00000188042 ADP ribosylation factor like GTPase 4C 2 234493041-234497053 Predicted intracellular proteins Evidence at protein level HPA028927 Uncertain Supported Plasma membrane
Cytosol Renal cancer:3.69e-8 (unfavourable), Endometrial cancer:2.90e-7 (unfavourable), Urothelial cancer:6.99e-5 (unfavourable) Expressed in all Mixed spleen: 72.0 Cell line enhanced RPTEC TERT1: 234.1;U-2197: 158.1 +RNF133 ENSG00000188050 Ring finger protein 133 7 122697712-122699156 Enzymes, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 182 testis: 60.9 lung: 0.3 Not detected +TMEM221 ENSG00000188051 Transmembrane protein 221 19 17435509-17448567 Predicted membrane proteins Evidence at protein level HPA041580 Approved Tissue enhanced Tissue enhanced parathyroid gland: 6.8 fallopian tube: 4.2 Cell line enhanced AN3-CA: 4.4;PC-3: 6.7;REH: 3.7 +TREML4 TLT4 ENSG00000188056 Triggering receptor expressed on myeloid cells like 4 6 41228324-41238882 Predicted membrane proteins Evidence at transcript level HPA065044 Uncertain Not detected Not detected spleen: 0.4 Not detected +RAB42 MGC45806 ENSG00000188060 RAB42, member RAS oncogene family 1 28592200-28595443 Predicted intracellular proteins Evidence at transcript level HPA050290 Approved Endoplasmic reticulum Mixed Mixed lymph node: 9.5 Cell line enhanced Hep G2: 11.8 +WNT7B ENSG00000188064 Wnt family member 7B 22 45920362-45977129 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced skin: 21.4 urinary bladder: 8.0 Cell line enhanced A549: 108.4;HeLa: 71.0;U-87 MG: 92.0 +C11orf95 MGC3032 ENSG00000188070 Chromosome 11 open reading frame 95 11 63759892-63768775 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045002 Approved Intermediate filaments Expressed in all Expressed in all endometrium: 24.6 Expressed in all +SCGB1C1 RYD5 ENSG00000188076 Secretoglobin family 1C member 1 11 193080-194573 Predicted secreted proteins No evidence Tissue enhanced Not detected bone marrow: 0.4 Not detected +PRSS45 TESSP5 ENSG00000188086 Protease, serine 45 3 46742092-46744755 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA060284 Uncertain Mixed Tissue enhanced epididymis: 9.8;parathyroid gland: 8.6 skeletal muscle: 3.7 Not detected +PLA2G4E FLJ45651 ENSG00000188089 Phospholipase A2 group IVE 15 41981582-42051190 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA041105 Enhanced Tissue enhanced Tissue enriched 10 skin: 20.4 esophagus,tonsil: 2.0 Not detected +GPR89B GPR89, GPR89C, SH120 ENSG00000188092 G protein-coupled receptor 89B 1 147928393-147993521 Predicted membrane proteins Evidence at protein level HPA076096 Approved Endoplasmic reticulum Mixed Expressed in all kidney: 31.2 Expressed in all +MESP2 bHLHc6, SCDO2 ENSG00000188095 Mesoderm posterior bHLH transcription factor 2 15 89760591-89778754 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Mixed cervix, uterine: 1.2 Cell line enhanced U-2197: 4.2 +FAM25A bA96C23.5 ENSG00000188100 Family with sequence similarity 25 member A 10 87020306-87024730 Predicted intracellular proteins Evidence at transcript level HPA044808 Uncertain Tissue enhanced Tissue enhanced esophagus: 315.5;skin: 125.9 tonsil: 54.6 Group enriched 6 A-431: 22.6;SK-BR-3: 55.0 +EYS bA166P24.2, bA307F22.3, bA74E24.1, C6orf178, C6orf179, C6orf180, dJ1018A4.2, dJ303F19.1, EGFL10, EGFL11, RP25, SPAM ENSG00000188107 Eyes shut homolog (Drosophila) 6 63719980-65707225 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027103 Uncertain Not detected Tissue enhanced testis: 1.4 adipose tissue: 0.8 Cell line enhanced Karpas-707: 1.1;SCLC-21H: 1.3 +C6orf132 bA7K24.2 ENSG00000188112 Chromosome 6 open reading frame 132 6 42101118-42142619 Predicted intracellular proteins Evidence at protein level HPA044588 Enhanced Approved Golgi apparatus
Cytosol Pancreatic cancer:4.90e-4 (unfavourable) Mixed Tissue enhanced esophagus: 80.8 skin: 49.9 Cell line enhanced A-431: 56.9;CACO-2: 48.3;CAPAN-2: 42.1 +DAZ1 DAZ, SPGY ENSG00000188120 Deleted in azoospermia 1 Y 23129355-23199094 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047113 Supported Not detected Tissue enhanced testis: 1.7 stomach: 0.8 Group enriched 15 U-266/70: 11.7;U-266/84: 17.1 +OR2AG2 OR2AG2P ENSG00000188124 Olfactory receptor family 2 subfamily AG member 2 11 6767987-6769055 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.3 Not detected +MAPK12 ERK6, p38gamma, PRKM12, SAPK-3, SAPK3 ENSG00000188130 Mitogen-activated protein kinase 12 22 50245450-50261825 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB025483, HPA054562 Enhanced Approved Nuclear speckles
Cytosol Renal cancer:5.00e-6 (unfavourable) Mixed Tissue enriched 6 skeletal muscle: 91.5 cerebral cortex: 15.7 Mixed +TMEM215 ENSG00000188133 Transmembrane protein 215 9 32783499-32787399 Predicted membrane proteins Evidence at protein level HPA052804, HPA063207 Uncertain Supported Nucleoplasm
Endoplasmic reticulum
Vesicles Tissue enriched Group enriched 5 cervix, uterine: 1.0;endometrium: 4.8;testis: 4.2;thyroid gland: 1.8 cerebral cortex: 0.5 Cell line enhanced NTERA-2: 1.9 +NUTM2G FAM22G ENSG00000188152 NUT family member 2G 9 96928310-96940253 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced testis: 2.0 skin: 1.0 Mixed +COL4A5 ASLN, ATS ENSG00000188153 Collagen type IV alpha 5 chain X 108439844-108697545 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA065449 Uncertain Lipid droplets Renal cancer:2.41e-5 (unfavourable) Expressed in all Mixed endometrium: 76.4 Cell line enhanced HHSteC: 80.3;HUVEC TERT2: 76.9;SiHa: 73.2;TIME: 73.5 +KRTAP10-6 KAP10.6, KAP18.6, KRTAP18-6, KRTAP18.6 ENSG00000188155 Keratin associated protein 10-6 21 44591268-44592505 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +AGRN AGRIN ENSG00000188157 Agrin 1 1020123-1056118 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA040090 Approved Supported Plasma membrane
Cytosol Liver cancer:4.62e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 33.2 Cell line enhanced EFO-21: 223.9 +NHS ENSG00000188158 NHS actin remodeling regulator X 17375420-17735994 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031497, HPA076257 Uncertain Supported Cell Junctions Endometrial cancer:1.68e-4 (favourable) Mixed Mixed endometrium: 7.9 Cell line enhanced EFO-21: 12.0;RPTEC TERT1: 14.5 +OTOG FLJ46346, mlemp, OTGN ENSG00000188162 Otogelin 11 17547373-17647150 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 16 testis: 1.6 all non-specific tissues: 0.0 Cell line enriched 12 CACO-2: 7.7 +FAM166A ENSG00000188163 Family with sequence similarity 166 member A 9 137243584-137247770 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA023307 Enhanced Not detected Tissue enriched 44 testis: 58.6 epididymis: 1.3 Not detected +TMPPE FLJ45032 ENSG00000188167 Transmembrane protein with metallophosphoesterase domain 3 33090421-33096801 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027019 Uncertain Approved Nucleoplasm
Mitochondria Mixed Mixed parathyroid gland: 4.1 Cell line enriched 6 BEWO: 26.4 +ZNF626 ENSG00000188171 Zinc finger protein 626 19 20620061-20661596 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA045631 Uncertain Approved Nucleoplasm
Nuclear membrane
Vesicles Mixed Expressed in all parathyroid gland: 52.8 Mixed +HEPACAM2 FLJ38683 ENSG00000188175 HEPACAM family member 2 7 93188586-93226524 Predicted membrane proteins Evidence at protein level Colorectal cancer:9.73e-5 (favourable) Mixed Tissue enhanced colon: 64.3;rectum: 103.1;small intestine: 53.6 duodenum: 30.2 Cell line enriched 47 SCLC-21H: 202.2 +SMTNL2 FLJ42461 ENSG00000188176 Smoothelin like 2 17 4583999-4608319 Predicted intracellular proteins Evidence at protein level Renal cancer:1.28e-4 (favourable) Tissue enhanced Group enriched 9 kidney: 26.8;skeletal muscle: 133.8 fallopian tube: 9.0 Group enriched 7 CACO-2: 40.8;SCLC-21H: 13.5 +ZC3H6 FLJ41410, FLJ45877, KIAA2035, ZC3HDC6 ENSG00000188177 Zinc finger CCCH-type containing 6 2 112275594-112340063 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036019, HPA036020, HPA076065 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all Mixed ovary: 7.6 Mixed +LAMTOR4 C7orf59 ENSG00000188186 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 7 100148907-100155944 Predicted intracellular proteins Evidence at protein level HPA020998 Enhanced Enhanced Vesicles Breast cancer:2.48e-4 (favourable), Cervical cancer:6.08e-4 (favourable) Expressed in all Expressed in all skin: 314.5 Expressed in all +PRKAR1B ENSG00000188191 Protein kinase cAMP-dependent type I regulatory subunit beta 7 549197-727650 Predicted intracellular proteins Evidence at protein level HPA026719 Approved Expressed in all Tissue enriched 9 cerebral cortex: 239.1 ovary: 26.3 Expressed in all +NUTM2B bA119F19.1, FAM22B ENSG00000188199 NUT family member 2B 10 79703227-79714681 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level Not detected Mixed testis: 2.2 Mixed +NCR3LG1 B7-H6, DKFZp686O24166 ENSG00000188211 Natural killer cell cytotoxicity receptor 3 ligand 1 11 17351726-17377341 Predicted membrane proteins Evidence at protein level HPA024137 Uncertain Renal cancer:4.21e-12 (favourable) Mixed Tissue enhanced parathyroid gland: 12.9 rectum: 5.6 Cell line enhanced HL-60: 42.1 +DCUN1D3 DKFZp686O0290, FLJ41725, MGC48972, SCCRO3 ENSG00000188215 Defective in cullin neddylation 1 domain containing 3 16 20854925-20900384 Predicted intracellular proteins Evidence at protein level HPA041983, HPA043511 Approved Approved Nucleoplasm
Cytosol Renal cancer:5.41e-6 (unfavourable) Expressed in all Mixed adipose tissue: 24.0 Expressed in all +POTEE A26C1, A26C1A, CT104.2, POTE-2, POTE2, POTE2gamma ENSG00000188219 POTE ankyrin domain family member E 2 131218067-131265278 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041264, HPA041271, HPA042822, HPA043260 Uncertain Not detected Tissue enhanced testis: 2.1 prostate: 0.7 Cell line enhanced AN3-CA: 1.0;BEWO: 1.3;K-562: 1.3;U-2 OS: 2.8 +ZNF793 ENSG00000188227 Zinc finger protein 793 19 37506939-37548762 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA034781 Uncertain Approved Nucleus
Nucleoli
Cytosol Mixed Mixed parathyroid gland: 15.7 Cell line enhanced AN3-CA: 12.6;U-266/70: 15.1 +TUBB4B Beta2, TUBB2C ENSG00000188229 Tubulin beta 4B class IVb 9 137241213-137243707 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010880, HPA043640, HPA046280 Enhanced Supported Microtubules Thyroid cancer:6.36e-6 (favourable), Endometrial cancer:4.91e-4 (favourable), Liver cancer:9.98e-4 (unfavourable) Expressed in all Expressed in all testis: 786.8 Expressed in all +AGAP4 AGAP8, CTGLF1, CTGLF5, Em:AC012044.1, MRIP2 ENSG00000188234 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 10 45825594-45853875 Predicted intracellular proteins Evidence at transcript level HPA042490 Uncertain Mixed Expressed in all skin: 24.7 Mixed +COMMD6 Acrg ENSG00000188243 COMM domain containing 6 13 75525219-75549439 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all ovary: 288.2 Expressed in all +PLA2G2A PLA2B, PLA2L ENSG00000188257 Phospholipase A2 group IIA 1 19975431-19980416 Enzymes, FDA approved drug targets, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA015236 Enhanced Uncertain Nucleus
Nucleoli Melanoma:1.49e-4 (favourable) Expressed in all Tissue enhanced colon: 108.4;rectum: 177.5;small intestine: 233.7 duodenum: 85.7 Group enriched 11 Hep G2: 50.2;RT4: 53.3 +IL17REL FLJ41993 ENSG00000188263 Interleukin 17 receptor E like 22 49994513-50012659 Predicted intracellular proteins Evidence at protein level HPA045546 Supported Mixed Tissue enhanced appendix: 3.1;lymph node: 2.4;tonsil: 4.0 stomach: 2.1 Not detected +HYKK AGPHD1, LOC123688 ENSG00000188266 Hydroxylysine kinase 15 78507564-78537372 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040706 Approved Approved Vesicles
Aggresome Mixed Mixed kidney: 12.5 Cell line enhanced HEK 293: 20.5 +OR7A5 HTPCR2 ENSG00000188269 Olfactory receptor family 7 subfamily A member 5 19 14792490-14835376 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA053823 Uncertain Tissue enriched Tissue enhanced epididymis: 5.5;parathyroid gland: 5.4;testis: 2.8 breast,seminal vesicle: 0.9 Not detected +C15orf62 LOC643338 ENSG00000188277 Chromosome 15 open reading frame 62 15 40770080-40772449 Predicted intracellular proteins Evidence at protein level HPA044636 Approved Mixed Tissue enhanced esophagus: 14.9;skin: 12.6 tonsil: 4.6 Cell line enhanced RPTEC TERT1: 13.6 +RUFY4 FLJ46536, ZFYVE31 ENSG00000188282 RUN and FYVE domain containing 4 2 218034960-218090581 Predicted intracellular proteins Evidence at protein level HPA037980 Uncertain Mixed Tissue enhanced spleen: 2.5 lymph node: 1.3 Cell line enriched 12 Karpas-707: 7.6 +ZNF383 FLJ35863 ENSG00000188283 Zinc finger protein 383 19 37217926-37248738 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063945 Approved Supported Nucleus
Nuclear membrane Urothelial cancer:3.71e-4 (favourable), Pancreatic cancer:9.97e-4 (favourable) Expressed in all Mixed thyroid gland: 9.2 Mixed +HES4 bHLHb42 ENSG00000188290 Hes family bHLH transcription factor 4 1 998962-1000172 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062465 Approved Nucleoplasm
Vesicles
Cytosol Liver cancer:2.99e-4 (unfavourable), Endometrial cancer:3.85e-4 (favourable), Renal cancer:6.27e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 7.5 Cell line enriched 8 HEK 293: 180.2 +IGFL1 UNQ644 ENSG00000188293 IGF like family member 1 19 46229752-46231243 Predicted secreted proteins Evidence at protein level HPA014001 Uncertain Group enriched Tissue enriched 22 esophagus: 97.7 tonsil: 4.4 Group enriched 8 HaCaT: 6.2;RT4: 20.8;SK-BR-3: 6.6 +ZNF669 FLJ12606 ENSG00000188295 Zinc finger protein 669 1 247099962-247104372 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044043 Uncertain Approved Nucleoli Renal cancer:4.59e-7 (favourable) Expressed in all Mixed testis: 8.7 Mixed +C19orf35 FLJ45778 ENSG00000188305 Chromosome 19 open reading frame 35 19 2274622-2282176 Predicted intracellular proteins Evidence at protein level HPA057806 Uncertain Mixed Mixed appendix: 1.8 Cell line enriched 13 HMC-1: 10.7 +LRRIQ4 LRRC64 ENSG00000188306 Leucine rich repeats and IQ motif containing 4 3 169821922-169837775 Predicted intracellular proteins Evidence at protein level HPA036706 Uncertain Mixed Tissue enriched 9 testis: 4.3 small intestine: 0.5 Cell line enhanced RT4: 1.3;T-47d: 1.3 +CENPP CENP-P, RP11-19J3.3 ENSG00000188312 Centromere protein P 9 92325484-92620533 Predicted intracellular proteins Evidence at protein level HPA021787, HPA058945 Uncertain Supported Nucleus
Nucleoli Head and neck cancer:3.65e-4 (favourable), Cervical cancer:3.91e-4 (favourable) Mixed Tissue enhanced skin: 25.2 parathyroid gland: 8.0 Expressed in all +PLSCR1 MMTRA1B ENSG00000188313 Phospholipid scramblase 1 3 146515180-146544864 Predicted intracellular proteins, Transporters Evidence at protein level HPA068923, CAB070421 Approved Supported Nucleus
Golgi apparatus
Plasma membrane Endometrial cancer:1.35e-4 (unfavourable) Expressed in all Expressed in all appendix: 114.2 Cell line enhanced BJ hTERT+ SV40 Large T+: 292.9;BJ hTERT+ SV40 Large T+ RasG12V: 404.0;SK-MEL-30: 418.1 +C3orf62 FLJ43654 ENSG00000188315 Chromosome 3 open reading frame 62 3 49268602-49277909 Predicted intracellular proteins Evidence at protein level HPA043328 Approved Nuclear speckles Urothelial cancer:1.62e-5 (favourable), Stomach cancer:3.29e-5 (favourable), Breast cancer:3.93e-4 (favourable), Liver cancer:5.20e-4 (unfavourable), Pancreatic cancer:8.15e-4 (favourable), Lung cancer:8.88e-4 (favourable), Head and neck cancer:9.72e-4 (favourable) Expressed in all Tissue enhanced testis: 28.5 ovary: 8.8 Expressed in all +ENO4 AC023283.3, C10orf134 ENSG00000188316 Enolase family member 4 10 116849512-116911788 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037938, HPA061509 Enhanced Mixed Tissue enhanced fallopian tube: 9.2;testis: 6.8 thyroid gland: 3.4 Cell line enhanced MCF7: 3.0;T-47d: 2.3 +ZNF559 MGC13105 ENSG00000188321 Zinc finger protein 559 19 9323772-9351162 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059632, HPA065485 Approved Supported Nucleoplasm
Cytosol Ovarian cancer:6.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 40.8 Mixed +SBK1 Sbk ENSG00000188322 SH3 domain binding kinase 1 16 28292519-28323849 Enzymes, Predicted membrane proteins Evidence at transcript level Cervical cancer:6.88e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 10.9;skeletal muscle: 12.0 parathyroid gland: 4.1 Cell line enhanced AF22: 27.9;NTERA-2: 29.2;REH: 29.2;SCLC-21H: 52.5;SH-SY5Y: 44.5 +OR6C6 ENSG00000188324 Olfactory receptor family 6 subfamily C member 6 12 55294288-55295232 G-protein coupled receptors, Predicted membrane proteins No evidence HPA051090 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +BSPH1 BSP1, ELSPBP2 ENSG00000188334 Binder of sperm protein homolog 1 19 47968046-47992170 Predicted secreted proteins Evidence at protein level HPA048335 Enhanced Not detected Tissue enriched 3118 epididymis: 468.2 testis: 0.1 Not detected +SLC38A3 G17, SN1 ENSG00000188338 Solute carrier family 38 member 3 3 50205246-50221486 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA031871 Approved Microtubules
Cytosol Tissue enriched Tissue enriched 7 liver: 174.0 cerebral cortex: 25.4 Cell line enhanced Hep G2: 33.9;SCLC-21H: 18.6 +OR6N2 ENSG00000188340 Olfactory receptor family 6 subfamily N member 2 1 158776682-158777635 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA056637 Uncertain Not detected Tissue enriched 12 bone marrow: 1.1 all non-specific tissues: 0.0 Not detected +GTF2F2 BTF4, RAP30, TFIIF ENSG00000188342 General transcription factor IIF subunit 2 13 45120515-45284909 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006912 Supported Supported Nucleus
Microtubules Head and neck cancer:1.65e-5 (unfavourable) Expressed in all Expressed in all skin: 26.3 Expressed in all +FAM92A FAM92A1, FLJ38979 ENSG00000188343 Family with sequence similarity 92 member A 8 93698561-93731527 Predicted intracellular proteins Evidence at protein level HPA034760, HPA058942 Enhanced Approved Mitochondria Expressed in all Tissue enriched 6 testis: 198.8 parathyroid gland: 32.4 Mixed +FOCAD FLJ20375, KIAA1797 ENSG00000188352 Focadhesin 9 20658309-20995955 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055015 Uncertain Uncertain Mitochondria Renal cancer:3.09e-8 (favourable), Liver cancer:4.41e-5 (unfavourable), Colorectal cancer:3.25e-4 (favourable) Expressed in all Expressed in all thyroid gland: 34.2 Mixed +PRR19 MGC70924 ENSG00000188368 Proline rich 19 19 42302098-42310821 Predicted intracellular proteins Evidence at protein level HPA070350 Approved Nucleus
Nucleoli
Nuclear bodies Mixed Tissue enriched 10 testis: 22.5 cerebral cortex: 2.1 Mixed +ZP3 ZP3-372, ZP3-424, ZP3A, ZP3B, ZPC ENSG00000188372 Zona pellucida glycoprotein 3 7 76397518-76442071 Predicted membrane proteins Evidence at protein level HPA054061 Supported Renal cancer:1.02e-6 (unfavourable) Expressed in all Mixed fallopian tube: 6.2 Cell line enhanced A549: 31.8;Karpas-707: 36.7;MCF7: 54.0 +C10orf99 AP-57, CSBF, FLJ21763, RLLV1833, UNQ1833 ENSG00000188373 Chromosome 10 open reading frame 99 10 84173738-84185294 Predicted secreted proteins Evidence at protein level HPA050920 Enhanced Renal cancer:1.20e-5 (unfavourable) Mixed Group enriched 11 colon: 239.2;esophagus: 185.4;rectum: 264.2 urinary bladder: 20.8 Cell line enriched 6 RT4: 37.2 +H3F3C H3.5 ENSG00000188375 H3 histone family member 3C 12 31791185-31792241 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA042570 Supported Mixed Tissue enriched 15 testis: 33.7 bone marrow: 2.2 Cell line enhanced SH-SY5Y: 2.6 +IFNA2 IFN-alphaA, IFNA ENSG00000188379 Interferon alpha 2 9 21384254-21385388 Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +JAKMIP3 bA140A10.5, C10orf14, C10orf39, FLJ37857, KIAA4091, NECC2 ENSG00000188385 Janus kinase and microtubule interacting protein 3 10 132104671-132184809 Predicted membrane proteins Evidence at protein level HPA022872 Uncertain Mixed Tissue enhanced cerebral cortex: 5.8 prostate: 2.2 Cell line enhanced A549: 2.2;U-266/84: 4.1 +PPP3R2 PPP3RL ENSG00000188386 Protein phosphatase 3 regulatory subunit B, beta 9 101591615-101595021 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA047157 Uncertain Approved Plasma membrane
Cytosol Not detected Tissue enriched 1372 testis: 137.1 all non-specific tissues: 0.0 Not detected +PDCD1 CD279, hSLE1, PD-1, PD1, SLEB2 ENSG00000188389 Programmed cell death 1 2 241849881-241858908 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035981, CAB038418, CAB076386 Enhanced Renal cancer:3.48e-7 (unfavourable), Endometrial cancer:9.44e-5 (favourable) Mixed Tissue enhanced lymph node: 12.0 appendix: 3.3 Group enriched 13 MOLT-4: 4.6;RPMI-8226: 4.0 +CLEC2A INPE5792, KACL, PILAR, UNQ5792 ENSG00000188393 C-type lectin domain family 2 member A 12 9898673-9932381 Predicted membrane proteins Evidence at protein level HPA048530, HPA072407 Approved Uncertain Plasma membrane Tissue enhanced Tissue enriched 14 skin: 67.7 breast: 4.7 Cell line enhanced BEWO: 5.9;fHDF/TERT166: 16.8;U-937: 42.5 +GPR21 ENSG00000188394 G protein-coupled receptor 21 9 123034527-123035696 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA041651 Uncertain Not detected Tissue enhanced cerebral cortex: 2.1 endometrium: 0.9 Cell line enriched 6 HBEC3-KT: 2.2 +TCTEX1D4 ENSG00000188396 Tctex1 domain containing 4 1 44805913-44806675 Predicted intracellular proteins Evidence at protein level HPA062652 Enhanced Endometrial cancer:1.58e-4 (favourable) Mixed Tissue enhanced fallopian tube: 5.9 epididymis: 1.7 Not detected +SELL CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR ENSG00000188404 Selectin L 1 169690667-169711698 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002144, HPA051972 Enhanced Approved Cytosol Renal cancer:4.96e-5 (unfavourable), Cervical cancer:2.25e-4 (favourable), Ovarian cancer:3.14e-4 (favourable), Breast cancer:3.76e-4 (favourable), Head and neck cancer:6.43e-4 (favourable) Expressed in all Tissue enhanced lymph node: 254.9;spleen: 219.3;tonsil: 179.1 appendix: 152.7 Cell line enhanced EFO-21: 9.7;MOLT-4: 16.7;U-266/70: 28.0;U-698: 12.2 +MAGEB5 CT3.3, MAGE-B5 ENSG00000188408 MAGE family member B5 X 26216169-26218270 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level HPA052627 Uncertain Not detected Not detected testis: 0.8 Not detected +CHM DXS540, REP-1, TCD ENSG00000188419 CHM, Rab escort protein 1 X 85861180-86047562 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003231, CAB016171 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 21.9 Expressed in all +NANOS2 NOS2, ZC2HC12B ENSG00000188425 Nanos C2HC-type zinc finger 2 19 45913214-45914870 Predicted intracellular proteins Evidence at protein level HPA014190 Approved Not detected Tissue enriched 37 testis: 3.6 all non-specific tissues: 0.0 Not detected +BLOC1S5 dJ303A1.3, MU, MUTED ENSG00000188428 Biogenesis of lysosomal organelles complex 1 subunit 5 6 8013567-8064414 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB025613 Uncertain Liver cancer:8.12e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 20.0 Expressed in all +CERKL RP26 ENSG00000188452 Ceramide kinase like 2 181536676-181680665 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035443, HPA035444, HPA043203 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:2.10e-4 (unfavourable), Pancreatic cancer:5.25e-4 (favourable) Expressed in all Tissue enhanced lymph node: 24.1 spleen: 22.4 Cell line enhanced HEL: 66.6;MOLT-4: 81.2;NB-4: 55.7;SCLC-21H: 75.7 +SLC24A5 JSX, OCA6 ENSG00000188467 Solute carrier family 24 member 5 15 48120972-48142672 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Group enriched 21 skin: 9.6;testis: 2.9 breast: 0.3 Cell line enriched 760 SK-MEL-30: 193.4 +IER5L bA247A12.2 ENSG00000188483 Immediate early response 5 like 9 129175552-129178262 Predicted intracellular proteins Evidence at transcript level HPA021327 Approved Nucleus Lung cancer:1.48e-6 (unfavourable) Expressed in all Mixed endometrium: 5.9 Cell line enhanced SiHa: 36.8 +H2AFX H2AX ENSG00000188486 H2A histone family member X 11 119093854-119095467 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012264, HPA041189, HPA051647 Supported Supported Nucleoplasm
Nuclear speckles Renal cancer:5.47e-9 (unfavourable), Liver cancer:1.51e-4 (unfavourable) Expressed in all Expressed in all lymph node: 18.7 Expressed in all +INSC ENSG00000188487 Inscuteable homolog (Drosophila) 11 15112424-15247208 Predicted intracellular proteins Evidence at protein level HPA039769 Enhanced Tissue enhanced Mixed small intestine: 2.7 Cell line enhanced ASC TERT1: 8.1;hTERT-HME1: 4.6;TIME: 10.5 +SERPINA5 PAI3, PCI, PLANH3, PROCI ENSG00000188488 Serpin family A member 5 14 94561442-94593120 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA056919 Approved Mitochondria Endometrial cancer:7.72e-4 (favourable) Tissue enhanced Tissue enhanced adrenal gland: 514.2;liver: 405.3;testis: 818.8 gallbladder: 250.7 Cell line enriched 10 Hep G2: 176.3 +C19orf54 FLJ41131 ENSG00000188493 Chromosome 19 open reading frame 54 19 40740856-40751553 Predicted intracellular proteins Evidence at protein level HPA059043, HPA059628 Approved Expressed in all Expressed in all parathyroid gland: 12.2 Expressed in all +LCTL FLJ33279, KLG, KLPH ENSG00000188501 Lactase like 15 66547179-66565979 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA071640 Approved Endoplasmic reticulum
Plasma membrane Group enriched Mixed cerebral cortex: 1.0 Cell line enhanced EFO-21: 5.3;NTERA-2: 5.2;U-2 OS: 15.2;U-251 MG: 5.3 +NCCRP1 FBXO50, LOC342897, NCCRP-1 ENSG00000188505 Non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 19 39196961-39201884 Predicted intracellular proteins Evidence at protein level HPA052812 Uncertain Approved Mitochondria Endometrial cancer:1.01e-4 (unfavourable) Mixed Group enriched 22 esophagus: 263.4;skin: 175.5;tonsil: 113.3 breast: 8.2 Cell line enriched 7 SK-BR-3: 23.1 +KRTDAP KDAP, UNQ467 ENSG00000188508 Keratinocyte differentiation associated protein 19 35487324-35495558 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA063474 Enhanced Group enriched Tissue enriched 11 skin: 4647.8 breast: 422.9 Cell line enriched 47 hTCEpi: 55.8 +COL25A1 ENSG00000188517 Collagen type XXV alpha 1 chain 4 108810721-109302657 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029107 Approved Endoplasmic reticulum
Vesicles
Cytosol Mixed Tissue enhanced testis: 20.4 adipose tissue: 7.5 Cell line enriched 6 HeLa: 37.1 +FAM83G FLJ41564, PAWS1 ENSG00000188522 Family with sequence similarity 83 member G 17 18968789-19004804 Predicted intracellular proteins Evidence at protein level HPA023369, HPA023940 Enhanced Supported Cytosol Stomach cancer:7.58e-6 (favourable), Liver cancer:8.29e-4 (unfavourable) Mixed Tissue enhanced skin: 64.4 esophagus: 24.2 Mixed +CFAP77 C9orf171, FLJ46082 ENSG00000188523 Cilia and flagella associated protein 77 9 132410043-132573317 Predicted intracellular proteins Evidence at protein level HPA021329, HPA024647, HPA061069 Enhanced Approved Cytosol Endometrial cancer:7.31e-4 (favourable) Tissue enhanced Group enriched 10 fallopian tube: 48.8;testis: 22.9 lung: 3.4 Cell line enhanced SH-SY5Y: 2.1 +SRSF10 FUSIP1, FUSIP2, PPP1R149, SFRS13, SFRS13A, SRp38, SRrp40, TASR1, TASR2 ENSG00000188529 Serine and arginine rich splicing factor 10 1 23964804-23980927 Predicted intracellular proteins Evidence at protein level HPA053805, HPA053831 Uncertain Supported Nucleoplasm Liver cancer:1.18e-6 (unfavourable), Renal cancer:1.01e-5 (unfavourable), Prostate cancer:1.74e-4 (unfavourable) Expressed in all Expressed in all endometrium: 100.9 Expressed in all +HBA2 HBA-T2 ENSG00000188536 Hemoglobin subunit alpha 2 16 172847-173710 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB038417, HPA043780 Enhanced Expressed in all Group enriched 27 bone marrow: 18369.0;placenta: 4302.7 spleen: 427.2 Group enriched 18 HEL: 802.0;K-562: 265.1 +DUSP28 DUSP26, VHP ENSG00000188542 Dual specificity phosphatase 28 2 240560054-240564014 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047456, CAB069448 Uncertain Uncertain Nuclear speckles
Cytosol Pancreatic cancer:1.84e-4 (favourable) Expressed in all Mixed skeletal muscle: 3.9 Mixed +C15orf52 FLJ43339 ENSG00000188549 Chromosome 15 open reading frame 52 15 40331452-40340967 Predicted intracellular proteins Evidence at protein level HPA040484, HPA041834 Approved Approved Nucleoplasm
Cytosol Expressed in all Mixed thyroid gland: 50.4 Cell line enhanced HaCaT: 108.4;WM-115: 137.0 +NBR1 1A1-3B, CA125, KIAA0049, M17S2 ENSG00000188554 NBR1, autophagy cargo receptor 17 43170481-43211689 Predicted intracellular proteins Evidence at protein level HPA022944, HPA022999, HPA023999 Approved Supported Nucleoplasm
Nuclear bodies
Vesicles Renal cancer:2.00e-5 (favourable) Expressed in all Expressed in all testis: 259.6 Expressed in all +OR2G6 ENSG00000188558 Olfactory receptor family 2 subfamily G member 6 1 248521647-248522597 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected kidney: 0.1 Not detected +RALGAPA2 AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2 ENSG00000188559 Ral GTPase activating protein catalytic alpha subunit 2 20 20389552-20712488 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042707, HPA043622 Uncertain Supported Plasma membrane
Cytosol Renal cancer:3.77e-5 (favourable) Expressed in all Expressed in all thyroid gland: 39.9 Group enriched 5 RT4: 88.7;SCLC-21H: 71.2 +NDOR1 bA350O14.9, NR1 ENSG00000188566 NADPH dependent diflavin oxidoreductase 1 9 137205685-137217009 Predicted intracellular proteins Evidence at protein level HPA024504 Approved Approved Nucleus
Intermediate filaments
Cytosol Expressed in all Mixed spleen: 14.1 Expressed in all +FBLL1 LOC345630 ENSG00000188573 Fibrillarin-like 1 5 168529116-168530634 Predicted intracellular proteins Evidence at transcript level HPA049546 Approved Nucleus
Nucleoli fibrillar center Mixed Tissue enhanced cerebral cortex: 19.0 testis: 4.3 Group enriched 6 SCLC-21H: 24.5;SH-SY5Y: 18.4 +NKAIN2 FAM77B, TCBA1 ENSG00000188580 Sodium/potassium transporting ATPase interacting 2 6 123804141-124825657 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at transcript level HPA045860 Approved Cytosol Mixed Tissue enriched 44 cerebral cortex: 46.1 adipose tissue,skeletal muscle: 1.0 Cell line enhanced HEK 293: 4.5;HEL: 5.8;Karpas-707: 7.5 +KRTAP1-1 HB2A, KAP1.1, KAP1.1A, KAP1.1B ENSG00000188581 Keratin associated protein 1-1 17 41040559-41041461 Predicted intracellular proteins Evidence at transcript level Not detected Not detected pancreas: 0.1 Not detected +PAQR9 FLJ41938 ENSG00000188582 Progestin and adipoQ receptor family member 9 3 142949164-142963682 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052798 Uncertain Tissue enriched Tissue enhanced heart muscle: 5.6;liver: 6.8;testis: 19.3 bone marrow: 3.4 Cell line enhanced A549: 3.0;AF22: 2.0;HEL: 2.1;NTERA-2: 2.5;U-266/70: 4.6;U-266/84: 2.4 +CLEC20A FLJ44005, LINC00083, NCRNA00083, RP4-593C16.2 ENSG00000188585 C-type lectin domain family 20 member A 1 178479247-178499634 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 6 testis: 3.3 lymph node: 0.5 Not detected +CFAP54 C12orf55, C12orf63, FLJ31514, FLJ44112 ENSG00000188596 Cilia and flagella associated protein 54 12 96489571-96875555 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039897 Enhanced Approved Microtubules
Cytosol Not detected Tissue enhanced testis: 11.0 fallopian tube: 8.5 Cell line enhanced TIME: 8.0 +CLN3 BTN1, BTS, JNCL ENSG00000188603 CLN3, battenin 16 28474111-28495575 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA063280 Uncertain Expressed in all Expressed in all placenta: 46.8 Expressed in all +FAM72B RP11-439A17.6 ENSG00000188610 Family with sequence similarity 72 member B 1 121167646-121185539 Predicted intracellular proteins Evidence at transcript level HPA043271, HPA067321 Uncertain Approved Vesicles
Plasma membrane
Cytosol Mixed Tissue enhanced lymph node: 9.7 tonsil: 6.2 Mixed +ASAH2 ENSG00000188611 N-acylsphingosine amidohydrolase 2 10 50182778-50248610 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA061171 Supported Approved Focal adhesion sites Mixed Group enriched 17 duodenum: 83.5;small intestine: 71.3 stomach: 4.6 Mixed +SUMO2 SMT3B, SMT3H2 ENSG00000188612 Small ubiquitin-like modifier 2 17 75165586-75182983 Predicted intracellular proteins Evidence at protein level CAB037314, HPA042123, HPA048064 Enhanced Approved Nucleoplasm
Nuclear bodies Renal cancer:5.23e-6 (unfavourable), Endometrial cancer:1.88e-5 (unfavourable), Liver cancer:2.12e-4 (unfavourable) Expressed in all Expressed in all endometrium: 342.9 Expressed in all +NANOS1 NOS1, ZC2HC12A ENSG00000188613 Nanos C2HC-type zinc finger 1 10 119029716-119033732 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB012219 Approved Supported Nucleoplasm
Cytosol Breast cancer:1.52e-4 (unfavourable) Mixed Tissue enhanced skeletal muscle: 13.2 thyroid gland: 11.9 Cell line enhanced SH-SY5Y: 85.4;SK-BR-3: 34.9;SK-MEL-30: 28.2 +HMX3 NKX5-1 ENSG00000188620 H6 family homeobox 3 10 123135962-123137741 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA069659 Approved Nucleus
Microtubule organizing center Mixed Not detected adipose tissue: 0.3 Cell line enhanced HEL: 4.7;K-562: 15.8;NB-4: 3.8;SiHa: 5.0 +IGFL3 UNQ483 ENSG00000188624 IGF like family member 3 19 46120071-46124674 Predicted secreted proteins Evidence at protein level HPA062776 Uncertain Tissue enhanced Tissue enriched 7 skin: 16.9 parathyroid gland: 2.5 Cell line enhanced BJ hTERT+: 3.1;hTEC/SVTERT24-B: 1.3;U-2 OS: 1.4;U-87 MG: 2.5 +GOLGA8M ENSG00000188626 Golgin A8 family member M 15 28701954-28738384 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enhanced testis: 3.7;thyroid gland: 11.0 placenta: 2.4 Group enriched 10 HEL: 1.1;U-937: 3.5 +ZNF177 ENSG00000188629 Zinc finger protein 177 19 9363020-9382617 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003141 Uncertain Not detected Tissue enhanced testis: 14.3 epididymis: 8.7 Mixed +LDOC1L dJ1033E15.2, DKFZp761O17121, Mar6, Mart6 ENSG00000188636 LDOC1 like 22 44492572-44498298 Predicted intracellular proteins Evidence at protein level HPA005697 Approved Approved Nuclear speckles
Cytosol Expressed in all Expressed in all cerebral cortex: 42.4 Mixed +DPYD DPD ENSG00000188641 Dihydropyrimidine dehydrogenase 1 97077743-97921049 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033241, HPA045210 Uncertain Pancreatic cancer:6.27e-4 (unfavourable) Expressed in all Expressed in all lung: 44.1 Mixed +S100A16 DT1P1A7, MGC17528, S100F ENSG00000188643 S100 calcium binding protein A16 1 153606886-153613145 Predicted intracellular proteins, Transporters Evidence at protein level HPA045841 Enhanced Enhanced Plasma membrane
Cytosol Lung cancer:3.14e-5 (unfavourable), Renal cancer:3.91e-5 (unfavourable), Pancreatic cancer:2.04e-4 (unfavourable), Liver cancer:3.18e-4 (unfavourable) Expressed in all Tissue enhanced esophagus: 1489.4 skin: 394.6 Mixed +PTAR1 ENSG00000188647 Protein prenyltransferase alpha subunit repeat containing 1 9 69709522-69759959 Predicted intracellular proteins Evidence at protein level HPA021248 Uncertain Approved Microtubule organizing center
Rods & Rings Renal cancer:4.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 35.5 Expressed in all +CC2D2B bA248J23.4, C10orf130 ENSG00000188649 Coiled-coil and C2 domain containing 2B 10 95907603-96032684 Predicted intracellular proteins Evidence at protein level HPA044091, HPA072122 Enhanced Approved Nucleoli Not detected Tissue enhanced testis: 21.3 thyroid gland: 7.3 Mixed +RNASE9 h461, RAK1 ENSG00000188655 Ribonuclease A family member 9 (inactive) 14 20556093-20560931 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 1199 epididymis: 119.9 all non-specific tissues: 0.0 Not detected +SAXO2 DKFZp666G057, FAM154B ENSG00000188659 Stabilizer of axonemal microtubules 2 15 82262810-82284930 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040487, HPA040833 Enhanced Approved Nucleoplasm
Golgi apparatus Mixed Tissue enhanced fallopian tube: 95.7 testis: 29.1 Cell line enhanced HaCaT: 9.3;K-562: 8.9;SCLC-21H: 9.3 +RHCE CD240CE, RH ENSG00000188672 Rh blood group CcEe antigens 1 25362249-25430192 Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Mixed Tissue enriched 6 bone marrow: 28.8 epididymis: 5.2 Group enriched 12 HEL: 76.1;K-562: 16.0 +C2orf80 GONDA1, LOC389073 ENSG00000188674 Chromosome 2 open reading frame 80 2 208165343-208190073 Predicted intracellular proteins Evidence at transcript level HPA042639 Approved Golgi apparatus Tissue enriched Tissue enriched 28 cerebral cortex: 37.5 testis: 1.3 Cell line enhanced NTERA-2: 1.7 +IDO2 INDOL1 ENSG00000188676 Indoleamine 2,3-dioxygenase 2 8 39934614-40016391 Predicted intracellular proteins Evidence at protein level Not detected Group enriched 8 liver: 2.7;placenta: 5.9 appendix,lymph node,testis: 0.5 Not detected +PARVB CGI-56 ENSG00000188677 Parvin beta 22 43999211-44172949 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA062601 Approved Cytosol Expressed in all Expressed in all skeletal muscle: 68.6 Mixed +SLC4A5 NBC4 ENSG00000188687 Solute carrier family 4 member 5 2 74216242-74343414 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA036621 Approved Tissue enriched Group enriched 6 testis: 30.9;thyroid gland: 44.9 skin: 6.3 Cell line enhanced U-266/70: 7.2 +UROS ENSG00000188690 Uroporphyrinogen III synthase 10 125784980-125823248 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA044038 Approved Approved Nucleoplasm
Cytosol Renal cancer:6.27e-4 (unfavourable) Expressed in all Expressed in all epididymis: 84.7 Expressed in all +OR56A5 OR56A5P ENSG00000188691 Olfactory receptor family 56 subfamily A member 5 11 5967177-5968494 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.1 Not detected +KRTAP24-1 KAP24.1 ENSG00000188694 Keratin associated protein 24-1 21 30281309-30282958 Predicted intracellular proteins Evidence at protein level HPA017604 Supported Not detected Not detected all non-specific tissues: 0.0 Not detected +ZDHHC9 CGI-89, CXorf11, ZDHHC10, ZNF379, ZNF380 ENSG00000188706 Zinc finger DHHC-type containing 9 X 129803288-129843909 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA031814 Uncertain Supported Golgi apparatus
Cytosol Cervical cancer:4.64e-5 (unfavourable), Breast cancer:9.77e-5 (unfavourable), Head and neck cancer:2.45e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 71.1 Expressed in all +ZBED6CL C7orf29 ENSG00000188707 ZBED6 C-terminal like 7 150329789-150332721 Predicted intracellular proteins Evidence at transcript level HPA019724, HPA055805 Approved Approved Nuclear membrane
Vesicles Renal cancer:1.38e-5 (unfavourable), Pancreatic cancer:2.44e-5 (favourable), Glioma:5.65e-5 (unfavourable), Breast cancer:9.48e-5 (favourable) Expressed in all Tissue enhanced adrenal gland: 31.7;parathyroid gland: 30.4 lymph node: 9.8 Cell line enhanced HDLM-2: 80.9;K-562: 33.8 +QRFP 26RFa, P518 ENSG00000188710 Pyroglutamylated RFamide peptide 9 130892702-130896812 Predicted secreted proteins Evidence at transcript level HPA043377 Uncertain Mixed Tissue enhanced prostate: 1.3 esophagus: 1.2 Cell line enhanced U-138 MG: 3.5 +DUPD1 DUSP27 ENSG00000188716 Dual specificity phosphatase and pro isomerase domain containing 1 10 75037836-75058514 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042964 Uncertain Not detected Tissue enriched 30 skeletal muscle: 24.4 prostate: 0.8 Not detected +SMIM15 C5orf43, DKFZP686E2158 ENSG00000188725 Small integral membrane protein 15 5 61157709-61162474 Predicted intracellular proteins Evidence at protein level Urothelial cancer:9.23e-4 (favourable) Expressed in all Expressed in all thyroid gland: 59.6 Mixed +OSTN ENSG00000188729 Osteocrin 3 191199241-191265615 Predicted secreted proteins Evidence at protein level CAB024997, CAB025649, HPA030878 Uncertain Not detected Tissue enhanced cerebral cortex: 4.4 cervix, uterine,epididymis: 2.0 Cell line enriched 30 U-2197: 36.4 +VWC2 PSST739, UNQ739 ENSG00000188730 Von Willebrand factor C domain containing 2 7 49773661-49921950 Predicted secreted proteins Evidence at protein level HPA055243 Approved Not detected Tissue enhanced heart muscle: 3.2;ovary: 6.1 cerebral cortex: 1.8 Not detected +FAM221A C7orf46, DKFZp686F0810, FLJ45875, MGC72075 ENSG00000188732 Family with sequence similarity 221 member A 7 23680130-23703249 Predicted intracellular proteins Evidence at protein level HPA019719, HPA026748, HPA026752 Enhanced Approved Cytosol Mixed Tissue enhanced testis: 34.7 fallopian tube: 14.6 Cell line enhanced MOLT-4: 20.7;SCLC-21H: 26.9;SH-SY5Y: 41.2 +TMEM120B ENSG00000188735 Transmembrane protein 120B 12 121712752-121783001 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014066 Uncertain Approved Nucleoli fibrillar center
Cytosol Liver cancer:1.66e-5 (unfavourable) Expressed in all Mixed endometrium: 11.7 Expressed in all +FSIP2 FLJ34780 ENSG00000188738 Fibrous sheath interacting protein 2 2 185738895-185833290 Predicted intracellular proteins Evidence at protein level HPA036139 Approved Microtubules
Mitochondria Not detected Tissue enriched 9 testis: 21.3 stomach: 2.4 Cell line enhanced RT4: 1.1 +RBM34 KIAA0117 ENSG00000188739 RNA binding motif protein 34 1 235131183-235161457 Predicted intracellular proteins Evidence at protein level HPA028606 Approved Supported Nucleus
Nucleoli Mixed Expressed in all testis: 35.5 Expressed in all +NOXA1 FLJ25475, NY-CO-31, SDCCAG31 ENSG00000188747 NADPH oxidase activator 1 9 137423350-137434406 Predicted intracellular proteins Evidence at protein level HPA044781 Uncertain Approved Vesicles Renal cancer:2.65e-4 (favourable) Expressed in all Expressed in all skin: 21.5 Cell line enhanced CAPAN-2: 11.1;EFO-21: 10.7;MCF7: 15.1;T-47d: 17.6 +TMEM198 MGC99813, TMEM198A ENSG00000188760 Transmembrane protein 198 2 219543663-219550595 Predicted membrane proteins Evidence at protein level HPA042385, HPA056598 Uncertain Approved Vesicles Pancreatic cancer:6.89e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 15.7 duodenum: 8.9 Cell line enhanced SCLC-21H: 23.4;SH-SY5Y: 18.3 +BCL2L15 Bfk, C1orf178, FLJ22588 ENSG00000188761 BCL2 like 15 1 113878168-113887547 Predicted intracellular proteins Evidence at protein level HPA029732, HPA029733 Enhanced Endometrial cancer:5.63e-4 (favourable) Tissue enhanced Tissue enhanced colon: 47.4;duodenum: 66.5;rectum: 52.2;small intestine: 64.3 stomach: 24.0 Cell line enhanced CAPAN-2: 22.4;EFO-21: 8.1;RPTEC TERT1: 5.6 +FZD9 CD349, FZD3 ENSG00000188763 Frizzled class receptor 9 7 73433783-73436120 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Tissue enhanced Mixed skeletal muscle,testis: 1.5 Cell line enhanced HEK 293: 4.1;NTERA-2: 3.5 +SPRED3 ENSG00000188766 Sprouty related EVH1 domain containing 3 19 38388421-38399587 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA071521 Uncertain Nucleoplasm
Plasma membrane
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 6.6 parathyroid gland: 2.6 Cell line enhanced TIME: 12.9 +OPTC ENSG00000188770 Opticin 1 203494143-203508864 Predicted secreted proteins Evidence at protein level HPA034951, HPA034952 Enhanced Tissue enriched Not detected testis: 0.6 Not detected +PLET1 C11orf34 ENSG00000188771 Placenta expressed transcript 1 11 112248479-112260860 Predicted membrane proteins Evidence at transcript level HPA040237 Uncertain Not detected Not detected skin: 0.4 Not detected +ADRB3 ENSG00000188778 Adrenoceptor beta 3 8 37962991-37966965 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA061969 Uncertain Not detected Tissue enhanced ovary: 8.9;placenta: 3.7 gallbladder: 2.2 Not detected +SKOR1 CORL1, FUSSEL15, LBXCOR1 ENSG00000188779 SKI family transcriptional corepressor 1 15 67819704-67834561 Predicted intracellular proteins Evidence at protein level HPA040673 Approved Not detected Not detected testis: 0.8 Cell line enhanced U-266/70: 1.8;U-266/84: 1.3;U-698: 1.4 +CATSPER4 ENSG00000188782 Cation channel sperm associated 4 1 26190561-26202968 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA045257 Enhanced Not detected Tissue enriched 97 testis: 9.6 all non-specific tissues: 0.0 Not detected +PRELP prolargin, SLRR2A ENSG00000188783 Proline and arginine rich end leucine rich repeat protein 1 203475828-203491352 Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:5.62e-6 (unfavourable), Colorectal cancer:9.70e-5 (unfavourable), Urothelial cancer:1.02e-4 (unfavourable) Expressed in all Mixed seminal vesicle: 108.0 Group enriched 7 ASC diff: 12.4;BJ: 6.5;fHDF/TERT166: 9.1 +PLA2G2E ENSG00000188784 Phospholipase A2 group IIE 1 19920009-19923617 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA064085 Uncertain Not detected Tissue enriched 11 tonsil: 2.3 small intestine: 0.2 Not detected +ZNF548 FLJ32932 ENSG00000188785 Zinc finger protein 548 19 57389850-57402992 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA066042 Uncertain Approved Nucleus Breast cancer:7.85e-4 (favourable) Expressed in all Expressed in all lymph node: 32.6 Mixed +MTF1 ENSG00000188786 Metal regulatory transcription factor 1 1 37809567-37859620 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028604, HPA028689 Uncertain Enhanced Nucleoplasm Expressed in all Mixed bone marrow: 13.1 Expressed in all +TMCO2 dJ39G22.2 ENSG00000188800 Transmembrane and coiled-coil domains 2 1 40245947-40251691 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 776 testis: 188.7 urinary bladder: 0.2 Not detected +SHISA6 FLJ45455 ENSG00000188803 Shisa family member 6 17 11241263-11564063 Predicted membrane proteins, Transporters Evidence at transcript level HPA023440 Uncertain Mixed Tissue enhanced cervix, uterine: 24.7 seminal vesicle: 10.2 Cell line enriched 8 NTERA-2: 2.2 +TMEM201 Ima1, NET5, RP13-15M17.2, SAMP1 ENSG00000188807 Transmembrane protein 201 1 9588922-9614873 Predicted membrane proteins Evidence at protein level CAB039039 Approved Supported Nucleus
Nuclear membrane Liver cancer:9.61e-8 (unfavourable), Cervical cancer:5.36e-4 (favourable) Expressed in all Mixed testis: 9.9 Expressed in all +NHLRC3 ENSG00000188811 NHL repeat containing 3 13 39038306-39050109 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA013738 Uncertain Expressed in all Expressed in all thyroid gland: 27.9 Expressed in all +HMX2 NKX5-2 ENSG00000188816 H6 family homeobox 2 10 123148122-123150672 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA043379 Uncertain Tissue enhanced Tissue enriched 6 kidney: 1.2 duodenum,prostate,small intestine: 0.1 Cell line enriched 12 REH: 34.4 +SNTN FLJ44379, S100AL ENSG00000188817 Sentan, cilia apical structure protein 3 63652668-63679020 Predicted intracellular proteins Evidence at protein level HPA043322, HPA058399 Enhanced Group enriched Tissue enriched 12 fallopian tube: 349.6 thyroid gland: 29.2 Not detected +ZDHHC11 FLJ13153, ZNF399 ENSG00000188818 Zinc finger DHHC-type containing 11 5 795606-850986 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA057886, HPA069008 Uncertain Approved Lipid droplets Mixed Mixed fallopian tube: 10.6 Cell line enhanced T-47d: 10.8 +FAM26F C6orf187, dJ93H18.5, INAM, OTTHUMP00000017061, OTTHUMP00000017062, RP1-93H18.5 ENSG00000188820 Family with sequence similarity 26 member F 6 116461370-116463779 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:9.31e-10 (unfavourable) Expressed in all Tissue enhanced spleen: 170.6 appendix: 80.5 Cell line enhanced Karpas-707: 33.4;RPMI-8226: 110.4;U-937: 46.8 +CNR2 CB2 ENSG00000188822 Cannabinoid receptor 2 1 23870526-23913362 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level CAB009719 Uncertain Tissue enriched Group enriched 6 appendix: 3.1;lymph node: 8.7;spleen: 7.9;tonsil: 6.9 bone marrow: 1.0 Group enriched 5 Daudi: 3.8;HEL: 4.0;HMC-1: 17.3;U-698: 9.4 +SLX4 BTBD12, FANCP, KIAA1784, KIAA1987 ENSG00000188827 SLX4 structure-specific endonuclease subunit 16 3581181-3611598 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049421, HPA066238 Approved Supported Nucleoplasm
Cell Junctions
Cytosol Expressed in all Tissue enhanced testis: 12.7 lymph node: 4.9 Expressed in all +GLRA4 ENSG00000188828 Glycine receptor alpha 4 X 103707224-103728655 Predicted membrane proteins Evidence at transcript level HPA044759 Uncertain Not detected Tissue enhanced smooth muscle: 2.8 parathyroid gland: 1.0 Cell line enriched 18 SCLC-21H: 2.8 +ENTPD8 NTPDase-8, UNQ2492 ENSG00000188833 Ectonucleoside triphosphate diphosphohydrolase 8 9 137434364-137441816 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA021509 Enhanced Approved Nucleoplasm
Vesicles
Cytosol Stomach cancer:7.17e-4 (favourable) Mixed Tissue enhanced colon: 21.7;duodenum: 28.7;small intestine: 31.6 rectum: 12.5 Cell line enhanced CAPAN-2: 4.8;RPMI-8226: 3.7;T-47d: 2.7 +RPL14 CTG-B33, hRL14, L14, RL14 ENSG00000188846 Ribosomal protein L14 3 40457292-40468587 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA004136 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all Expressed in all breast: 312.8 Expressed in all +BEND4 CCDC4, FLJ35632, FLJ43965 ENSG00000188848 BEN domain containing 4 4 42110938-42152878 Predicted intracellular proteins Evidence at protein level HPA036850 Uncertain Approved Nucleus
Nucleoli fibrillar center
Cytosol Group enriched Tissue enhanced prostate: 5.3;testis: 17.7 lymph node: 2.5 Cell line enhanced HAP1: 35.3;HEL: 19.3;MOLT-4: 10.7;U-698: 9.6 +FAM78B ENSG00000188859 Family with sequence similarity 78 member B 1 166057426-166166969 Predicted intracellular proteins Evidence at transcript level HPA052789, HPA073246 Uncertain Approved Golgi apparatus
Vesicles Mixed Not detected adipose tissue,cerebral cortex,duodenum,stomach,testis: 0.2 Group enriched 7 HDLM-2: 8.8;SK-MEL-30: 6.5;U-2 OS: 2.3;WM-115: 2.2 +ZNF563 FLJ34797 ENSG00000188868 Zinc finger protein 563 19 12317477-12333720 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042136 Uncertain Expressed in all Tissue enhanced testis: 25.7 thyroid gland: 8.5 Mixed +TMC3 ENSG00000188869 Transmembrane channel like 3 15 81331217-81374213 Predicted membrane proteins Evidence at protein level HPA040265, HPA040510 Enhanced Supported Cytosol Tissue enhanced Tissue enriched 137 parathyroid gland: 252.6 epididymis: 1.8 Mixed +FBF1 ALB, FBF-1, FLJ00103, KIAA1863 ENSG00000188878 Fas binding factor 1 17 75909574-75941140 Predicted intracellular proteins Evidence at protein level HPA023677 Supported Centrosome Mixed Tissue enhanced testis: 32.9 skin: 15.4 Mixed +KLRG2 CLEC15B, FLJ44186 ENSG00000188883 Killer cell lectin like receptor G2 7 139452690-139483712 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018199 Uncertain Lung cancer:8.61e-4 (favourable) Tissue enriched Tissue enhanced lung: 4.4;parathyroid gland: 5.7;thyroid gland: 6.8 kidney: 2.7 Cell line enhanced BEWO: 14.0;HAP1: 15.9;SCLC-21H: 8.6;SK-BR-3: 23.3 +ASTL ovastacin, SAS1B ENSG00000188886 Astacin like metalloendopeptidase 2 96123850-96138436 Enzymes, Predicted secreted proteins Evidence at protein level HPA015620 Uncertain Mixed Tissue enhanced bone marrow: 2.4 seminal vesicle: 1.4 Not detected +MSL1 DKFZp686P24239, hMSL1, MSL-1 ENSG00000188895 Male specific lethal 1 homolog 17 40122298-40136916 Predicted intracellular proteins Evidence at protein level HPA022800, HPA023567 Uncertain Enhanced Nucleoplasm Renal cancer:3.06e-6 (unfavourable) Expressed in all Expressed in all testis: 107.0 Expressed in all +CTD-3088G3.8 ENSG00000188897 16 11359845-11523588 Predicted intracellular proteins Evidence at transcript level HPA042154 Uncertain Not detected Tissue enhanced appendix: 5.3;skin: 4.3 testis: 2.8 Cell line enhanced Daudi: 2.2;HDLM-2: 3.2 +LRRK2 DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2 ENSG00000188906 Leucine rich repeat kinase 2 12 40196744-40369285 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA014293, CAB037160 Approved Approved Nucleus
Vesicles Renal cancer:3.02e-6 (favourable) Group enriched Expressed in all lung: 95.4 Cell line enhanced A549: 7.4;ASC TERT1: 5.6;RPTEC TERT1: 6.7 +BSX BSX1 ENSG00000188909 Brain specific homeobox 11 122977570-122981720 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA015654 Uncertain Not detected Not detected testis: 0.2 Not detected +GJB3 CX31, DFNA2, EKV ENSG00000188910 Gap junction protein beta 3 1 34781189-34786369 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA074472 Supported Vesicles
Cell Junctions Pancreatic cancer:7.56e-5 (unfavourable), Lung cancer:4.56e-4 (unfavourable) Mixed Tissue enhanced esophagus: 33.6;skin: 77.3 tonsil: 11.6 Cell line enhanced A-431: 76.8;CAPAN-2: 106.8;HaCaT: 87.5;HBEC3-KT: 60.8;hTCEpi: 98.5 +FAM196A C10orf141, FLJ45557, INSYN2 ENSG00000188916 Family with sequence similarity 196 member A 10 127135426-127196158 Predicted intracellular proteins Evidence at protein level HPA035898, HPA035899 Uncertain Group enriched Tissue enhanced cerebral cortex: 3.2 prostate: 1.3 Group enriched 7 SCLC-21H: 3.2;U-87 MG: 5.2 +TRMT2B CXorf34, FLJ12687 ENSG00000188917 TRNA methyltransferase 2 homolog B X 101009346-101052116 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003745, HPA035120, HPA040814 Uncertain Approved Nucleoplasm
Nuclear bodies Renal cancer:2.30e-7 (favourable), Breast cancer:1.58e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 21.5 Expressed in all +HACD4 Em:AL662879.1, PTPLAD2 ENSG00000188921 3-hydroxyacyl-CoA dehydratase 4 9 20999515-21031636 Enzymes, Predicted membrane proteins Evidence at protein level HPA058666 Uncertain Ovarian cancer:3.14e-4 (favourable), Renal cancer:6.77e-4 (unfavourable) Mixed Mixed lung: 12.6 Cell line enhanced BJ hTERT+: 14.0;HDLM-2: 10.0;U-937: 10.5 +CFAP126 C1orf192, Flattop, Fltp ENSG00000188931 Cilia and flagella associated protein 126 1 161364731-161367874 Predicted intracellular proteins Evidence at protein level HPA045904 Enhanced Not detected Tissue enriched 9 fallopian tube: 228.1 testis: 25.0 Cell line enhanced CAPAN-2: 2.3;SCLC-21H: 1.0 +NYX CLRP, CSNB1, CSNB1A, CSNB4 ENSG00000188937 Nyctalopin X 41447434-41475710 Disease related genes, Predicted secreted proteins Evidence at protein level Not detected Not detected kidney: 0.3 Cell line enhanced HDLM-2: 2.3 +FAM120AOS C9orf10OS ENSG00000188938 Family with sequence similarity 120A opposite strand 9 93446494-93453592 Predicted intracellular proteins Evidence at transcript level HPA021475 Approved Liver cancer:2.95e-5 (unfavourable), Renal cancer:6.04e-4 (favourable) Expressed in all Expressed in all thyroid gland: 50.3 Expressed in all +UTS2B U2B, URP, UTS2D ENSG00000188958 Urotensin 2B 3 191267168-191330536 Predicted secreted proteins Evidence at transcript level HPA026992 Uncertain Uncertain Mitochondria Not detected Mixed duodenum: 5.3 Mixed +C9orf152 bA470J20.2 ENSG00000188959 Chromosome 9 open reading frame 152 9 110190048-110208189 Predicted intracellular proteins Evidence at protein level HPA050769 Approved Supported Nucleus Endometrial cancer:7.22e-5 (favourable) Mixed Tissue enhanced rectum: 44.5 colon: 32.5 Group enriched 6 SK-BR-3: 6.9;T-47d: 16.7 +NOC2L DKFZP564C186, NET15, NET7, NIR, PPP1R112 ENSG00000188976 NOC2 like nucleolar associated transcriptional repressor 1 944204-959309 Predicted intracellular proteins Evidence at protein level HPA044258, HPA062195 Approved Enhanced Nucleoli Expressed in all Expressed in all skin: 42.0 Expressed in all +MSANTD1 C4orf44, LOC345222 ENSG00000188981 Myb/SANT DNA binding domain containing 1 4 3244369-3271738 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 7 cerebral cortex: 1.9;testis: 2.4 epididymis,lung,spleen: 0.3 Not detected +AADACL3 ENSG00000188984 Arylacetamide deacetylase like 3 1 12716115-12728759 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced placenta: 1.3 skin: 0.7 Not detected +NELFB COBRA1, KIAA1182, NELF-B ENSG00000188986 Negative elongation factor complex member B 9 137255173-137273546 Predicted intracellular proteins Evidence at protein level HPA020259 Enhanced Enhanced Nucleoplasm Renal cancer:4.31e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 47.4 Expressed in all +SLC15A5 ENSG00000188991 Solute carrier family 15 member 5 12 16188485-16277685 Predicted membrane proteins, Transporters No evidence HPA041638 Uncertain Not detected Not detected testis: 0.3 Not detected +LIPI CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5 ENSG00000188992 Lipase I 21 14108813-14210891 Disease related genes, Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 120 epididymis: 577.5 thyroid gland: 4.8 Not detected +LRRC66 ENSG00000188993 Leucine rich repeat containing 66 4 51993702-52017620 Predicted membrane proteins Evidence at transcript level HPA014549, HPA027839 Uncertain Mixed Tissue enhanced duodenum: 22.5;small intestine: 20.5 rectum: 6.4 Cell line enhanced ASC TERT1: 1.0;CAPAN-2: 1.8 +ZNF292 bA393I2.3, KIAA0530, ZFP292, Zn-15, Zn-16 ENSG00000188994 Zinc finger protein 292 6 87152833-87264196 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA032154, HPA050618 Uncertain Approved Nucleus
Nuclear membrane Expressed in all Expressed in all endometrium: 17.1 Expressed in all +HUS1B ENSG00000188996 HUS1 checkpoint clamp component B 6 655939-656963 Predicted intracellular proteins Evidence at protein level HPA034511, HPA063449 Approved Nucleoplasm
Cytosol Mixed Tissue enhanced testis: 1.2 bone marrow: 0.4 Cell line enhanced HEK 293: 1.6;U-266/84: 1.5;WM-115: 2.2 +KCTD21 KCASH2 ENSG00000188997 Potassium channel tetramerization domain containing 21 11 78171249-78188822 Predicted intracellular proteins Evidence at protein level HPA041964 Uncertain Approved Cytosol Thyroid cancer:9.57e-5 (favourable) Expressed in all Mixed thyroid gland: 18.8 Expressed in all +SBSN HLAR698, UNQ698 ENSG00000189001 Suprabasin 19 35523367-35528351 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA062568, HPA067734 Enhanced Approved Vesicles Group enriched Group enriched 12 esophagus: 1055.9;skin: 2690.8 tonsil: 151.8 Cell line enhanced ASC diff: 42.6;ASC TERT1: 75.3;HSkMC: 106.4;U-2197: 48.0;U-87 MG: 117.4 +ADAT2 DEADC1, dJ20N2.1, TAD2 ENSG00000189007 Adenosine deaminase, tRNA specific 2 6 143422832-143450673 Predicted intracellular proteins Evidence at protein level HPA035479 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all Mixed skin: 13.0 Expressed in all +KIR2DL4 103AS, 15.212, CD158D ENSG00000189013 Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 19 54803535-54814517 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Mixed Not detected all non-specific tissues: 0.0 Not detected +MAGEB16 ENSG00000189023 MAGE family member B16 X 35798342-35803735 Predicted intracellular proteins Evidence at protein level HPA055743 Uncertain Tissue enhanced Tissue enriched 63 testis: 6.2 all non-specific tissues: 0.0 Group enriched 207 K-562: 12.2;U-266/70: 45.6 +VHLL VHLP, VLP ENSG00000189030 Von Hippel-Lindau tumor suppressor like 1 156298624-156299299 Predicted intracellular proteins Evidence at protein level Not detected Not detected esophagus,gallbladder,testis: 0.1 Not detected +DUSP21 ENSG00000189037 Dual specificity phosphatase 21 X 44844004-44844888 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 41 testis: 9.9 small intestine: 0.2 Not detected +ZNF567 MGC45586 ENSG00000189042 Zinc finger protein 567 19 36687612-36727701 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023937 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Mixed testis: 16.1 Mixed +NDUFA4 CI-9k, MLRQ ENSG00000189043 NDUFA4, mitochondrial complex associated 7 10931951-10940256 Disease related genes, Predicted membrane proteins Evidence at protein level HPA055323 Supported Mitochondria Renal cancer:4.61e-8 (favourable) Expressed in all Expressed in all heart muscle: 251.7 Expressed in all +ANKDD1B ENSG00000189045 Ankyrin repeat and death domain containing 1B 5 75611459-75671846 Predicted intracellular proteins Evidence at transcript level HPA059722 Uncertain Renal cancer:2.30e-7 (favourable) Mixed Tissue enhanced fallopian tube: 3.5 rectum: 2.4 Cell line enhanced RPMI-8226: 1.5 +ALKBH2 ABH2, MGC90512 ENSG00000189046 AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase 12 109088188-109093631 Enzymes, Predicted intracellular proteins Evidence at protein level CAB011198, HPA045392, HPA051976 Approved Enhanced Nucleus Renal cancer:1.41e-5 (unfavourable), Breast cancer:6.67e-5 (favourable), Urothelial cancer:8.67e-4 (favourable) Expressed in all Expressed in all skin: 27.0 Expressed in all +RNFT1 PTD016 ENSG00000189050 Ring finger protein, transmembrane 1 17 59952240-59964761 Predicted membrane proteins Evidence at protein level HPA013739 Approved Nucleoli Thyroid cancer:2.57e-4 (favourable), Colorectal cancer:6.57e-4 (favourable), Lung cancer:7.48e-4 (favourable) Expressed in all Tissue enriched 9 testis: 114.0 epididymis: 12.6 Expressed in all +RNF222 ENSG00000189051 Ring finger protein 222 17 8390704-8397826 Predicted membrane proteins Evidence at transcript level HPA048916 Uncertain Tissue enhanced Group enriched 6 esophagus: 9.7;skin: 4.1;tonsil: 2.0 bone marrow: 0.9 Cell line enriched 7 SK-BR-3: 5.1 +CGB5 HCG ENSG00000189052 Chorionic gonadotropin beta subunit 5 19 49043884-49045311 Predicted secreted proteins Evidence at protein level HPA038925, HPA038934 Supported Approved Cytosol Stomach cancer:1.18e-5 (unfavourable), Urothelial cancer:9.47e-4 (unfavourable) Tissue enhanced Tissue enriched 68 placenta: 31.7 pancreas,skin,testis: 0.4 Group enriched 24 BEWO: 99.4;U-251 MG: 40.1 +RELN PRO1598, RL ENSG00000189056 Reelin 7 103471784-103989516 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046512 Approved Plasma membrane
Focal adhesion sites Tissue enhanced Tissue enhanced liver: 17.8 cerebral cortex: 7.3 Cell line enhanced Hep G2: 43.5;PC-3: 11.6;SCLC-21H: 17.5;SH-SY5Y: 17.2;TIME: 29.6 +FAM111B CANP ENSG00000189057 Family with sequence similarity 111 member B 11 59107185-59127410 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038637 Uncertain Approved Nucleus
Cytosol Pancreatic cancer:1.17e-5 (unfavourable), Liver cancer:1.76e-4 (unfavourable) Expressed in all Mixed lymph node: 14.9 Mixed +APOD ENSG00000189058 Apolipoprotein D 3 195568702-195584205 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA040520 Enhanced Approved Plasma membrane Thyroid cancer:4.12e-4 (unfavourable), Breast cancer:5.51e-4 (favourable), Stomach cancer:6.02e-4 (unfavourable) Expressed in all Tissue enriched 7 breast: 4620.2 adipose tissue: 670.2 Cell line enhanced ASC diff: 1866.1;ASC TERT1: 1018.4;WM-115: 301.1 +H1F0 H10, H1FV ENSG00000189060 H1 histone family member 0 22 37805093-37807436 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000843 Enhanced Supported Nucleus
Nuclear bodies
Golgi apparatus
Actin filaments Renal cancer:7.68e-7 (favourable) Expressed in all Expressed in all bone marrow: 420.2 Cell line enhanced U-2 OS: 855.8 +GAGE2A CT4.2, GAGE2 ENSG00000189064 G antigen 2A X 49589529-49596827 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Mixed Tissue enriched 560 testis: 176.3 cerebral cortex: 0.3 Cell line enhanced Karpas-707: 62.0;T-47d: 279.0;WM-115: 324.4 +LITAF FLJ38636, PIG7, SIMPLE, TP53I7 ENSG00000189067 Lipopolysaccharide induced TNF factor 16 11547722-11636381 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006960 Approved Supported Nucleoplasm
Vesicles
Cytosol Glioma:1.78e-4 (unfavourable), Testis cancer:6.25e-4 (unfavourable) Expressed in all Expressed in all appendix: 225.8 Mixed +VSTM1 UNQ3033 ENSG00000189068 V-set and transmembrane domain containing 1 19 54040825-54063953 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA059365 Approved Vesicles Mixed Tissue enriched 38 bone marrow: 35.4 urinary bladder: 0.9 Not detected +TMEM120A NET29, TMPIT ENSG00000189077 Transmembrane protein 120A 7 75986837-75994659 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Expressed in all Expressed in all testis: 72.8 Expressed in all +ARID2 BAF200, DKFZp686G052, FLJ30619, KIAA1557 ENSG00000189079 AT-rich interaction domain 2 12 45729665-45908040 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063044 Supported Nucleoplasm
Plasma membrane Head and neck cancer:5.75e-4 (favourable) Expressed in all Expressed in all testis: 47.3 Expressed in all +FAM25G bA301J7.4 ENSG00000189090 Family with sequence similarity 25 member G 10 47487219-47491693 Predicted intracellular proteins Evidence at transcript level HPA044808 Uncertain Not detected Tissue enriched 15 skin: 87.4 breast: 5.8 Cell line enriched 25 SK-BR-3: 16.5 +SF3B3 KIAA0017, RSE1, SAP130, SF3b130 ENSG00000189091 Splicing factor 3b subunit 3 16 70523788-70577670 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041134, HPA042986 Supported Supported Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 40.9 Expressed in all +PRSS48 ESSPL ENSG00000189099 Protease, serine 48 4 151277171-151291453 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA053801 Uncertain Not detected Tissue enhanced testis: 1.4 skin: 0.4 Not detected +IL1RAPL2 IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1 ENSG00000189108 Interleukin 1 receptor accessory protein like 2 X 104566315-105767829 Predicted membrane proteins Evidence at protein level HPA036128, HPA036129 Uncertain Not detected Tissue enhanced parathyroid gland: 4.8 adrenal gland: 1.9 Cell line enhanced fHDF/TERT166: 1.1;hTERT-HME1: 4.3;NTERA-2: 1.0;RT4: 1.6 +BLOC1S3 BLOS3, HPS8 ENSG00000189114 Biogenesis of lysosomal organelles complex 1 subunit 3 19 45178745-45181801 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050111 Approved Golgi apparatus Renal cancer:3.89e-9 (unfavourable), Urothelial cancer:6.86e-4 (favourable) Expressed in all Mixed skin: 12.1 Expressed in all +SP6 Epfn, KLF14 ENSG00000189120 Sp6 transcription factor 17 47844908-47855874 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024516, HPA044469 Supported Nucleoplasm
Mitotic spindle
Centrosome Lung cancer:2.11e-6 (unfavourable), Urothelial cancer:5.72e-4 (favourable), Stomach cancer:6.39e-4 (favourable) Mixed Tissue enhanced placenta: 32.5;seminal vesicle: 14.7 skin: 7.2 Cell line enriched 5 BEWO: 88.4 +ANKRD34B DP58 ENSG00000189127 Ankyrin repeat domain 34B 5 80556755-80570488 Predicted intracellular proteins Evidence at protein level HPA043327 Uncertain Approved Nucleoplasm
Mitochondria
Cytosol Tissue enhanced Tissue enhanced bone marrow: 1.1;lymph node: 1.0;tonsil: 1.1 kidney: 0.7 Cell line enriched 23 RPTEC TERT1: 71.4 +PLAC9 ENSG00000189129 Placenta specific 9 10 80131682-80145359 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043469 Uncertain Ovarian cancer:6.60e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 87.5 breast: 68.4 Cell line enhanced ASC diff: 67.4;ASC TERT1: 59.6;BEWO: 31.0 +FAM47B FLJ35782 ENSG00000189132 Family with sequence similarity 47 member B X 34942796-34944915 Predicted intracellular proteins Evidence at protein level HPA046829, HPA050996 Uncertain Not detected Tissue enriched 133 testis: 13.3 all non-specific tissues: 0.0 Not detected +NKAPL bA424I5.1, C6orf194 ENSG00000189134 NFKB activating protein like 6 28259320-28260958 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 15 testis: 53.4 seminal vesicle: 3.6 Cell line enhanced ASC diff: 2.2;BJ: 1.2;fHDF/TERT166: 1.7;HHSteC: 3.9;HSkMC: 2.2 +FSCB C14orf155, DKFZP434F1017 ENSG00000189139 Fibrous sheath CABYR binding protein 14 44504342-44507279 Predicted intracellular proteins Evidence at protein level HPA003546 Supported Not detected Tissue enriched 520 testis: 51.9 all non-specific tissues: 0.0 Not detected +CLDN4 CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8 ENSG00000189143 Claudin 4 7 73799542-73832693 Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB002610 Enhanced Supported Plasma membrane Renal cancer:3.46e-10 (favourable), Ovarian cancer:3.28e-4 (unfavourable) Mixed Mixed colon: 208.6 Cell line enhanced A-431: 285.9;BEWO: 354.2;CAPAN-2: 613.4;MCF7: 279.4;PC-3: 419.8;SK-BR-3: 439.0 +ZNF573 FLJ30921 ENSG00000189144 Zinc finger protein 573 19 37735833-37817300 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA042776 Uncertain Approved Intermediate filaments
Cytosol Mixed Mixed thyroid gland: 4.2 Mixed +GRAPL ENSG00000189152 GRB2 related adaptor protein like 17 19127469-19159176 Predicted intracellular proteins Evidence at transcript level HPA051796, HPA066654 Uncertain Approved Centrosome Not detected Tissue enhanced lymph node: 26.7;spleen: 32.0 tonsil: 21.5 Group enriched 6 Daudi: 27.6;HUVEC TERT2: 13.0;TIME: 34.3;U-698: 24.5 +FAM47E FLJ42946, LOC100129583 ENSG00000189157 Family with sequence similarity 47 member E 4 76214040-76283780 Predicted intracellular proteins Evidence at transcript level HPA053331 Uncertain Approved Plasma membrane
Cytosol Mixed Tissue enhanced fallopian tube: 28.1 thyroid gland: 16.3 Mixed +HN1 ARM2, HN1A ENSG00000189159 Hematological and neurological expressed 1 17 75135248-75168281 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059729 Approved Supported Nucleus
Nuclear membrane
Nucleoli Liver cancer:1.58e-7 (unfavourable), Renal cancer:1.77e-7 (unfavourable), Ovarian cancer:4.91e-4 (favourable) Expressed in all Expressed in all testis: 422.3 Expressed in all +ZNF527 KIAA1829 ENSG00000189164 Zinc finger protein 527 19 37371061-37393066 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA037740, HPA037741 Uncertain Approved Nuclear speckles
Golgi apparatus Mixed Mixed parathyroid gland: 4.8 Mixed +ZAR1L Z3CXXC7 ENSG00000189167 Zygote arrest 1-like 13 32303700-32315344 Predicted intracellular proteins Evidence at transcript level HPA041319 Uncertain Not detected Not detected testis: 0.7 Not detected +KRTAP10-12 KAP10.12, KRTAP18-12, KRTAP18.12 ENSG00000189169 Keratin associated protein 10-12 21 44697172-44698044 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +S100A13 ENSG00000189171 S100 calcium binding protein A13 1 153618787-153631360 Predicted intracellular proteins Evidence at protein level HPA019592, CAB025494 Approved Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Renal cancer:1.97e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 331.5 Mixed +ZNF33A FLJ23404, KIAA0065, KOX31, KOX5, ZNF11A, ZNF33, ZZAPK ENSG00000189180 Zinc finger protein 33A 10 38010650-38065088 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056638 Approved Expressed in all Expressed in all parathyroid gland: 35.1 Expressed in all +OR14I1 OR5BU1, OR5BU1P ENSG00000189181 Olfactory receptor family 14 subfamily I member 1 1 248681369-248682304 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 5 cerebral cortex: 3.4 prostate: 0.6 Not detected +KRT77 KRT1B ENSG00000189182 Keratin 77 12 52689626-52703463 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045934 Enhanced Approved Nuclear membrane
Plasma membrane Mixed Tissue enriched 12 skin: 308.7 breast: 26.2 Cell line enriched 33 HaCaT: 3.2 +PCDH18 KIAA1562, PCDH68L ENSG00000189184 Protocadherin 18 4 137518918-137532494 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017976 Approved Approved Golgi apparatus
Cytosol Renal cancer:3.21e-4 (unfavourable), Urothelial cancer:4.71e-4 (unfavourable) Mixed Mixed placenta: 64.5 Cell line enhanced AF22: 148.8;ASC diff: 122.0;ASC TERT1: 137.4;fHDF/TERT166: 114.4;HHSteC: 109.9;HSkMC: 146.3 +DCAF8L2 WDR42C ENSG00000189186 DDB1 and CUL4 associated factor 8 like 2 X 27590382-27748821 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 52 testis: 40.5 ovary: 0.7 Cell line enriched 7 U-2 OS: 9.9 +ZNF600 DKFZp686F06123, KR-ZNF1 ENSG00000189190 Zinc finger protein 600 19 52764195-52786791 Predicted intracellular proteins, Transcription factors Evidence at protein level Renal cancer:4.98e-7 (unfavourable), Urothelial cancer:1.11e-5 (favourable) Expressed in all Mixed spleen: 7.8 Cell line enhanced RT4: 17.0 +BTBD8 ENSG00000189195 BTB domain containing 8 1 92080305-92184725 Predicted intracellular proteins Evidence at transcript level HPA024216, HPA035311, HPA035312 Uncertain Approved Nucleoplasm Not detected Mixed parathyroid gland: 3.7 Cell line enhanced ASC TERT1: 2.1;BEWO: 2.4 +MAOA ENSG00000189221 Monoamine oxidase A X 43654907-43746824 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB009437, HPA054807, HPA059299 Enhanced Enhanced Mitochondria Expressed in all Mixed small intestine: 248.3 Cell line enhanced ASC diff: 108.7;HHSteC: 249.1;hTCEpi: 61.9;RT4: 102.5 +C15orf61 LOC145853 ENSG00000189227 Chromosome 15 open reading frame 61 15 67521068-67530143 Predicted intracellular proteins Evidence at protein level HPA062820 Approved Nucleoli
Vesicles
Cytosol Renal cancer:5.31e-5 (favourable) Expressed in all Mixed cerebral cortex: 11.0 Mixed +NUGGC C8orf80, HMFN0672, SLIP-GC ENSG00000189233 Nuclear GTPase, germinal center associated 8 28021964-28083871 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enhanced lymph node: 22.9;tonsil: 21.4 liver: 11.0 Cell line enhanced Daudi: 84.7;Karpas-707: 28.5;U-698: 59.8 +TSPYL1 TSPYL ENSG00000189241 TSPY like 1 6 116276578-116279903 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031970, HPA031971 Approved Supported Nucleus
Nucleoli Renal cancer:1.48e-13 (favourable), Pancreatic cancer:5.40e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 191.9 Expressed in all +SPANXN3 CT11.8, SPANX-N3 ENSG00000189252 SPANX family member N3 X 143508735-143517475 Predicted intracellular proteins Evidence at transcript level HPA045652 Approved Nucleus
Nucleoli fibrillar center Not detected Tissue enriched 58 testis: 52.1 duodenum: 0.8 Cell line enriched 6 U-2 OS: 1.9 +TRIM64B ENSG00000189253 Tripartite motif containing 64B 11 89869282-89876017 Predicted intracellular proteins Evidence at transcript level HPA045370 Approved Not detected Tissue enriched 18 placenta: 3.1 testis,thyroid gland: 0.1 Not detected +PNRC2 ENSG00000189266 Proline rich nuclear receptor coactivator 2 1 23959109-23963462 Predicted intracellular proteins Evidence at protein level HPA027820, HPA045837 Uncertain Supported Nucleoplasm
Golgi apparatus Liver cancer:7.97e-5 (unfavourable), Melanoma:1.41e-4 (unfavourable), Urothelial cancer:4.05e-4 (favourable), Breast cancer:6.02e-4 (favourable) Expressed in all Expressed in all thyroid gland: 203.4 Expressed in all +DRICH1 C22orf43 ENSG00000189269 Aspartate rich 1 22 23608452-23632321 Predicted intracellular proteins Evidence at protein level HPA020446 Approved Nucleus
Nucleoli Mixed Group enriched 8 epididymis: 20.8;parathyroid gland: 23.9;testis: 81.2 endometrium: 5.4 Cell line enhanced CACO-2: 9.2 +GJB5 CX31.1 ENSG00000189280 Gap junction protein beta 5 1 34755047-34758512 Cancer-related genes, Predicted membrane proteins Evidence at transcript level HPA038146 Uncertain Pancreatic cancer:1.54e-4 (unfavourable) Group enriched Group enriched 6 esophagus: 56.4;skin: 77.4 tonsil: 11.4 Cell line enhanced A-431: 25.3;HaCaT: 80.2;HBEC3-KT: 29.1;hTCEpi: 106.2;RT4: 40.6 +FHIT AP3Aase, FRA3B ENSG00000189283 Fragile histidine triad 3 59749310-61251459 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB002684, HPA018840, HPA018909 Enhanced Approved Nucleoli fibrillar center
Plasma membrane Renal cancer:1.36e-4 (favourable) Mixed Expressed in all kidney: 26.8 Cell line enhanced U-266/70: 27.6 +ALKAL2 AUGA, FAM150B ENSG00000189292 ALK and LTK ligand 2 2 279558-288851 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced adrenal gland: 257.4 ovary: 83.0 Cell line enriched 22 AF22: 137.0 +ZKSCAN3 ZF47, Zfp47, ZNF306, ZNF309, ZSCAN35 ENSG00000189298 Zinc finger with KRAB and SCAN domains 3 6 28349914-28369177 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009637, HPA060116 Approved Enhanced Nucleoplasm Glioma:6.55e-4 (favourable) Expressed in all Mixed parathyroid gland: 10.1 Mixed +FOXR2 FOXN6, MGC21658 ENSG00000189299 Forkhead box R2 X 55623400-55625325 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034487, HPA057358 Uncertain Supported Nucleoplasm Tissue enhanced Tissue enriched 15 testis: 2.8 epididymis: 0.1 Group enriched 107 NTERA-2: 12.2;SH-SY5Y: 11.3;U-266/70: 5.4;U-266/84: 13.9 +RRP7A CGI-96 ENSG00000189306 Ribosomal RNA processing 7 homolog A 22 42509968-42519802 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001586, HPA046768 Approved Approved Nucleus
Nucleoli
Cell Junctions Liver cancer:1.21e-5 (unfavourable) Expressed in all Expressed in all epididymis: 47.3 Expressed in all +LIN54 CXCDC1, DKFZp686L1814, JC8.6, MIP120, TCX1 ENSG00000189308 Lin-54 DREAM MuvB core complex component 4 82909973-83012926 Predicted intracellular proteins Evidence at protein level HPA056606 Approved Approved Cytosol Renal cancer:1.06e-4 (favourable) Expressed in all Mixed thyroid gland: 17.2 Expressed in all +FAM53B bA12J10.2, KIAA0140, smp ENSG00000189319 Family with sequence similarity 53 member B 10 124619292-124744269 Predicted intracellular proteins Evidence at protein level HPA037751, HPA037752 Approved Approved Cytosol Renal cancer:4.81e-7 (favourable), Pancreatic cancer:7.00e-6 (favourable), Head and neck cancer:1.97e-4 (favourable), Stomach cancer:3.26e-4 (favourable), Cervical cancer:4.96e-4 (favourable) Expressed in all Mixed lymph node: 37.9 Expressed in all +FAM180A HWKM1940, UNQ1940 ENSG00000189320 Family with sequence similarity 180 member A 7 135728348-135748846 Predicted secreted proteins Evidence at protein level HPA021224 Uncertain Mixed Tissue enhanced gallbladder: 25.5 heart muscle: 10.4 Cell line enhanced BJ hTERT+: 45.6;fHDF/TERT166: 44.5;U-138 MG: 55.9;U-2197: 239.9 +C6orf222 DKFZp779B1540 ENSG00000189325 Chromosome 6 open reading frame 222 6 36315757-36336885 Predicted intracellular proteins Evidence at protein level HPA038407, HPA058189 Uncertain Group enriched Tissue enhanced duodenum: 24.7;small intestine: 26.4 rectum: 6.2 Not detected +SPANXN4 CT11.9, SPANX-N4 ENSG00000189326 SPANX family member N4 X 143025918-143034702 Predicted intracellular proteins Evidence at transcript level HPA045730 Uncertain Not detected Tissue enriched 227 testis: 22.7 all non-specific tissues: 0.0 Not detected +S100A14 BCMP84, S100A15 ENSG00000189334 S100 calcium binding protein A14 1 153614255-153616986 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027613 Enhanced Supported Nuclear bodies
Plasma membrane
Cell Junctions
Cytosol Mixed Tissue enhanced esophagus: 2205.9 skin: 591.6 Group enriched 9 A-431: 692.6;HaCaT: 944.8;HBEC3-KT: 1089.8;hTCEpi: 1601.4;SK-BR-3: 1180.8 +KAZN FLJ43806, KAZRIN, KIAA1026 ENSG00000189337 Kazrin, periplakin interacting protein 1 13892792-15118043 Predicted intracellular proteins Evidence at protein level HPA032095, HPA032096 Approved Supported Nucleoplasm
Nuclear speckles
Cytosol Renal cancer:1.20e-6 (favourable) Mixed Tissue enhanced spleen: 118.3 parathyroid gland: 42.3 Cell line enhanced AN3-CA: 79.3 +SLC35E2B ENSG00000189339 Solute carrier family 35 member E2B 1 1659529-1692728 Predicted membrane proteins, Transporters Evidence at protein level HPA045641, HPA062711 Uncertain Uncertain Nucleus Urothelial cancer:5.15e-4 (favourable), Head and neck cancer:7.64e-4 (favourable) Expressed in all Expressed in all smooth muscle: 47.2 Expressed in all +TOGARAM2 Crescerin-2, FAM179A, FLJ43249, LOC165186 ENSG00000189350 TOG array regulator of axonemal microtubules 2 2 28956611-29061373 Predicted intracellular proteins Evidence at protein level HPA037561, HPA037562 Uncertain Not detected Tissue enriched 5 fallopian tube: 13.7 lung: 2.5 Mixed +SPATA31D4 FAM75D4, FLJ43859 ENSG00000189357 SPATA31 subfamily D member 4 9 81928514-81934948 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 49 testis: 4.8 all non-specific tissues: 0.0 Not detected +NEMP2 TMEM194B ENSG00000189362 Nuclear envelope integral membrane protein 2 2 190504342-190534722 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA057719 Approved Nucleoplasm Renal cancer:6.42e-4 (unfavourable) Expressed in all Mixed testis: 5.6 Mixed +ALG1L ALG1L1 ENSG00000189366 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase like 3 125929275-125937039 Predicted intracellular proteins Evidence at transcript level HPA036108 Uncertain Glioma:1.82e-4 (favourable), Urothelial cancer:6.24e-4 (favourable) Expressed in all Tissue enhanced epididymis: 13.1;urinary bladder: 14.8 skin: 6.8 Cell line enhanced CACO-2: 13.2;CAPAN-2: 12.6;HaCaT: 13.5;MCF7: 23.1;T-47d: 18.5 +KIAA0408 ENSG00000189367 KIAA0408 6 127440343-127459391 Predicted intracellular proteins Evidence at protein level HPA044035, HPA053341 Uncertain Approved Nucleoplasm
Cytosol Not detected Tissue enhanced cerebral cortex: 43.8 lung: 30.8 Cell line enhanced AF22: 21.1;SCLC-21H: 62.8;SH-SY5Y: 28.1 +GSPT2 eRF3b, FLJ10441 ENSG00000189369 G1 to S phase transition 2 X 51743431-51746232 Predicted intracellular proteins Evidence at protein level HPA044769 Approved Supported Cytosol Expressed in all Expressed in all testis: 24.5 Cell line enhanced NTERA-2: 47.4;PC-3: 49.6 +TBC1D28 FLJ40244 ENSG00000189375 TBC1 domain family member 28 17 18635006-18661950 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 70 testis: 18.1 spleen,tonsil: 0.2 Not detected +C8orf76 FLJ14825 ENSG00000189376 Chromosome 8 open reading frame 76 8 123219957-123241398 Predicted intracellular proteins Evidence at transcript level HPA023708 Uncertain Uncertain Nucleoplasm
Cytosol Renal cancer:5.95e-11 (unfavourable), Endometrial cancer:1.61e-4 (unfavourable), Breast cancer:9.95e-4 (unfavourable) Expressed in all Expressed in all placenta: 16.1 Expressed in all +CXCL17 Dcip1, DMC, UNQ473, VCC1 ENSG00000189377 C-X-C motif chemokine ligand 17 19 42428288-42443048 Predicted secreted proteins Evidence at protein level Lung cancer:4.92e-5 (favourable), Pancreatic cancer:4.63e-4 (unfavourable) Mixed Tissue enhanced lung: 193.5;stomach: 289.7 esophagus: 83.1 Cell line enhanced RT4: 1.8 +OTUD6A DUBA2, FLJ25831, HSHIN6 ENSG00000189401 OTU deubiquitinase 6A X 70062491-70064179 Enzymes, Predicted intracellular proteins Evidence at protein level HPA053304 Enhanced Tissue enriched Tissue enriched 14 testis: 9.5 thyroid gland: 0.7 Not detected +HMGB1 DKFZp686A04236, HMG1, HMG3, SBP-1 ENSG00000189403 High mobility group box 1 13 30456704-30617597 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003506, CAB005873 Supported Supported Nucleus Expressed in all Expressed in all lymph node: 781.8 Expressed in all +MMP23B MIFR, MIFR-1, MMP22 ENSG00000189409 Matrix metallopeptidase 23B 1 1632095-1635263 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Tissue enhanced Mixed gallbladder,placenta: 4.1 Cell line enhanced HHSteC: 3.5;NTERA-2: 1.8;U-266/70: 2.5 +SH2D5 ENSG00000189410 SH2 domain containing 5 1 20719732-20732837 Predicted intracellular proteins Evidence at protein level HPA030182 Supported Cytosol Tissue enhanced Group enriched 7 cerebral cortex: 16.6;placenta: 5.1;testis: 9.9 thyroid gland: 1.5 Cell line enhanced HBEC3-KT: 34.9;hTERT-HME1: 46.6 +ZFP92 ZNF897 ENSG00000189420 ZFP92 zinc finger protein X 153418322-153426481 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA003030 Uncertain Tissue enhanced Mixed fallopian tube: 5.3 Cell line enhanced HDLM-2: 3.5;HMC-1: 3.1;U-937: 4.8 +NCR1 CD335, LY94, NK-p46, NKP46 ENSG00000189430 Natural cytotoxicity triggering receptor 1 19 54906150-54916140 CD markers, Predicted membrane proteins Evidence at protein level HPA049311 Approved Endoplasmic reticulum Tissue enhanced Not detected spleen: 0.6 Not detected +RASSF10 ENSG00000189431 Ras association domain family member 10 11 13009577-13012106 Predicted intracellular proteins Evidence at transcript level HPA040406 Approved Vesicles
Cytosol Renal cancer:4.12e-5 (favourable), Head and neck cancer:2.76e-4 (favourable) Mixed Tissue enhanced fallopian tube: 5.4 parathyroid gland: 3.8 Cell line enhanced A549: 8.6;CAPAN-2: 7.5;HaCaT: 11.6;HMC-1: 5.6;RPTEC TERT1: 9.8 +GJB4 CX30.3 ENSG00000189433 Gap junction protein beta 4 1 34759741-34763724 Disease related genes, Predicted membrane proteins Evidence at protein level HPA055112 Supported Cell Junctions Pancreatic cancer:3.24e-5 (unfavourable), Cervical cancer:5.48e-4 (favourable) Group enriched Tissue enriched 6 skin: 27.7 epididymis: 4.6 Cell line enhanced A-431: 4.0;HaCaT: 5.8;HBEC3-KT: 3.1;hTCEpi: 2.0;RPTEC TERT1: 1.9;RT4: 2.4 +OR2L13 OR2L14 ENSG00000196071 Olfactory receptor family 2 subfamily L member 13 1 248098649-248100922 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 4.0 prostate: 1.0 Not detected +BLOC1S2 BLOS2, BORCS2, FLJ30135, MGC10120 ENSG00000196072 Biogenesis of lysosomal organelles complex 1 subunit 2 10 100273280-100286712 Predicted intracellular proteins Evidence at protein level HPA048088, HPA055010 Approved Expressed in all Expressed in all cerebral cortex: 101.8 Expressed in all +SYCP2 SCP2 ENSG00000196074 Synaptonemal complex protein 2 20 59863563-59933655 Predicted intracellular proteins Evidence at protein level HPA062401, HPA065613 Supported Nucleoplasm
Plasma membrane
Cytosol Group enriched Group enriched 8 breast: 17.7;testis: 76.9 prostate: 6.0 Cell line enhanced MOLT-4: 43.5;SiHa: 97.9;T-47d: 77.3 +ZNF724 ZNF724P ENSG00000196081 Zinc finger protein 724 19 23221599-23250390 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Mixed esophagus: 2.9 Mixed +IL1RAP C3orf13, IL-1RAcP, IL1R3 ENSG00000196083 Interleukin 1 receptor accessory protein 3 190514051-190659750 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035293 Uncertain Approved Vesicles
Cytosol Renal cancer:2.16e-7 (unfavourable), Pancreatic cancer:1.31e-4 (unfavourable), Urothelial cancer:6.29e-4 (unfavourable) Expressed in all Tissue enhanced liver: 113.0;placenta: 53.7 gallbladder: 19.8 Cell line enhanced SK-MEL-30: 193.6 +PTPRT KIAA0283, RPTPrho ENSG00000196090 Protein tyrosine phosphatase, receptor type T 20 42072752-43189970 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017336, CAB069423 Approved Tissue enhanced Group enriched 5 cerebral cortex: 24.3;fallopian tube: 17.4 placenta: 4.0 Cell line enhanced BEWO: 1.1 +MYBPC1 ENSG00000196091 Myosin binding protein C, slow type 12 101568353-101686018 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021004, HPA027614 Enhanced Breast cancer:4.76e-5 (favourable) Tissue enhanced Tissue enriched 31 skeletal muscle: 3918.4 prostate: 125.8 Not detected +PAX5 BSAP ENSG00000196092 Paired box 5 9 36833275-37034185 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026269, CAB026869, HPA056394, HPA068498 Enhanced Approved Nucleoplasm
Vesicles
Cytosol Mixed Tissue enhanced lymph node: 48.5;spleen: 26.2;tonsil: 33.2 appendix: 19.5 Group enriched 6 Daudi: 48.5;REH: 181.0;U-698: 61.2 +OR5K4 ENSG00000196098 Olfactory receptor family 5 subfamily K member 4 3 98353854-98354819 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR6M1 ENSG00000196099 Olfactory receptor family 6 subfamily M member 1 11 123805335-123806387 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA048674 Uncertain Not detected Not detected testis: 0.2 Not detected +SPOCK3 testican-3 ENSG00000196104 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 4 166733384-167234796 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA075020 Approved Nucleus
Nucleoli
Golgi apparatus Tissue enhanced Tissue enriched 7 parathyroid gland: 800.5 prostate: 120.0 Cell line enhanced PC-3: 2.4;RH-30: 6.7;SCLC-21H: 3.5 +ZNF676 ENSG00000196109 Zinc finger protein 676 19 22179091-22196951 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enriched Tissue enhanced parathyroid gland: 4.4;testis: 4.0 thyroid gland: 3.0 Cell line enriched 9 NTERA-2: 7.0 +ZNF699 FLJ38144, hang ENSG00000196110 Zinc finger protein 699 19 9294275-9309838 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058287 Uncertain Mixed Mixed parathyroid gland: 4.9 Cell line enhanced U-138 MG: 14.3 +TDRD7 PCTAIRE2BP ENSG00000196116 Tudor domain containing 7 9 97411950-97496125 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB020800, HPA022250, HPA024529 Approved Supported Nucleoplasm
Cytoplasmic bodies Renal cancer:4.76e-5 (favourable), Liver cancer:5.91e-4 (unfavourable) Expressed in all Expressed in all testis: 64.1 Cell line enhanced HDLM-2: 49.4 +CCDC189 C16orf93, MGC104706 ENSG00000196118 Coiled-coil domain containing 189 16 30757423-30762710 Predicted intracellular proteins Evidence at protein level HPA041806, HPA046289 Approved Supported Cytosol Mixed Tissue enhanced fallopian tube: 14.6 testis: 8.6 Mixed +OR8A1 OST025 ENSG00000196119 Olfactory receptor family 8 subfamily A member 1 11 124569997-124571142 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.4 Not detected +KIAA0895L LOC653319 ENSG00000196123 KIAA0895 like 16 67175602-67184040 Predicted intracellular proteins Evidence at transcript level HPA065996 Approved Approved Nucleoplasm
Vesicles Pancreatic cancer:3.16e-4 (favourable) Expressed in all Mixed cerebral cortex: 25.4 Expressed in all +HLA-DRB1 HLA-DR1B ENSG00000196126 Major histocompatibility complex, class II, DR beta 1 6 32578769-32589848 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB015400, CAB034021, HPA043151 Enhanced Expressed in all Tissue enhanced lung: 868.4 lymph node: 619.6 Cell line enhanced HDLM-2: 1095.2;U-87 MG: 302.0 +VN1R2 V1RL2 ENSG00000196131 Vomeronasal 1 receptor 2 19 53258292-53261837 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA044551 Uncertain Not detected Mixed small intestine: 2.4 Not detected +MYT1 MTF1, MYTI, NZF2, PLPB1, ZC2H2C1, ZC2HC4A ENSG00000196132 Myelin transcription factor 1 20 64151791-64242253 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006303 Uncertain Supported Nucleoplasm
Cytosol Tissue enhanced Group enriched 7 adrenal gland: 2.5;cerebral cortex: 5.7 testis: 0.6 Cell line enhanced REH: 3.3;SCLC-21H: 16.5;SH-SY5Y: 3.0 +SERPINA3 AACT, ACT ENSG00000196136 Serpin family A member 3 14 94612377-94624055 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000893, HPA002560, CAB016647 Enhanced Breast cancer:8.92e-4 (favourable) Mixed Group enriched 6 cervix, uterine: 515.4;liver: 2304.3 gallbladder: 228.3 Cell line enriched 6 Hep G2: 302.6 +AKR1C3 DDX, HAKRB, HSD17B5, KIAA0119, PGFS ENSG00000196139 Aldo-keto reductase family 1 member C3 10 5035354-5107686 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010874, HPA068265 Enhanced Approved Nucleus
Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Renal cancer:1.22e-4 (unfavourable), Liver cancer:1.96e-4 (unfavourable) Expressed in all Expressed in all duodenum: 398.6 Cell line enhanced A549: 1217.9;AN3-CA: 359.6;ASC diff: 507.5;Hep G2: 391.2;RT4: 424.5 +SPATS2L DNAPTP6, SGNP ENSG00000196141 Spermatogenesis associated serine rich 2 like 2 200305881-200482263 Predicted intracellular proteins Evidence at protein level HPA055427, HPA066310 Uncertain Enhanced Nucleoli
Cytosol Pancreatic cancer:7.43e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 167.5 Mixed +ZNF250 MGC9718, ZFP647, ZNF647 ENSG00000196150 Zinc finger protein 250 8 144876497-144902168 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020853 Uncertain Supported Nuclear speckles Renal cancer:2.43e-7 (favourable), Urothelial cancer:8.26e-4 (favourable) Expressed in all Expressed in all thyroid gland: 20.1 Expressed in all +WDSUB1 FLJ36175, UBOX6, WDSAM1 ENSG00000196151 WD repeat, sterile alpha motif and U-box domain containing 1 2 159235793-159286799 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036840, HPA058172 Uncertain Approved Nucleus
Nucleoli
Cytosol Liver cancer:2.67e-4 (unfavourable), Cervical cancer:3.35e-4 (favourable) Expressed in all Expressed in all thyroid gland: 27.9 Expressed in all +ZNF79 pT7 ENSG00000196152 Zinc finger protein 79 9 127424374-127445372 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028977 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:6.04e-7 (favourable), Pancreatic cancer:5.42e-5 (favourable), Endometrial cancer:6.83e-5 (favourable), Lung cancer:5.96e-4 (favourable) Expressed in all Mixed testis: 11.4 Expressed in all +S100A4 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98 ENSG00000196154 S100 calcium binding protein A4 1 153543613-153550136 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002618, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228 Enhanced Enhanced Plasma membrane Head and neck cancer:4.03e-5 (favourable), Renal cancer:2.90e-4 (unfavourable) Expressed in all Expressed in all lung: 990.6 Cell line enhanced BJ hTERT+: 4403.5;fHDF/TERT166: 3054.2 +PLEKHG4 ARHGEF44, DKFZP434I216, SCA4 ENSG00000196155 Pleckstrin homology and RhoGEF domain containing G4 16 67277510-67289499 Predicted intracellular proteins Evidence at protein level HPA055696 Approved Cell Junctions Renal cancer:6.72e-9 (unfavourable) Expressed in all Tissue enhanced testis: 41.5 ovary: 18.8 Mixed +KRTAP4-3 KAP4.3 ENSG00000196156 Keratin associated protein 4-3 17 41167231-41168194 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 11 HDLM-2: 1.1 +FAT4 CDHF14, CDHR11, FAT-J ENSG00000196159 FAT atypical cadherin 4 4 125316399-125492932 Cancer-related genes, Disease related genes, Predicted membrane proteins Evidence at protein level HPA052819 Approved Approved Cytosol Renal cancer:1.89e-4 (favourable) Mixed Mixed parathyroid gland: 9.6 Cell line enhanced HUVEC TERT2: 11.5;TIME: 17.8 +C8orf86 FLJ43582 ENSG00000196166 Chromosome 8 open reading frame 86 8 38510834-38528662 Predicted intracellular proteins Evidence at transcript level HPA025066 Uncertain Not detected Tissue enhanced duodenum: 1.0 small intestine: 0.5 Not detected +KIF19 FLJ37300, KIF19A ENSG00000196169 Kinesin family member 19 17 74326210-74355820 Predicted intracellular proteins Evidence at protein level HPA043638, HPA073303 Enhanced Approved Plasma membrane
Actin filaments
Centrosome Mixed Tissue enhanced fallopian tube: 19.0;spleen: 6.6 duodenum: 2.9 Cell line enriched 13 SCLC-21H: 5.1 +OR6K2 ENSG00000196171 Olfactory receptor family 6 subfamily K member 2 1 158699678-158700652 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF681 FLJ31526 ENSG00000196172 Zinc finger protein 681 19 23739195-23758891 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Mixed testis: 4.6 Cell line enhanced HDLM-2: 15.0 +ACADSB ACAD7, SBCAD ENSG00000196177 Acyl-CoA dehydrogenase, short/branched chain 10 123008979-123058311 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041458 Enhanced Supported Mitochondria Renal cancer:6.37e-12 (favourable), Pancreatic cancer:3.40e-4 (favourable) Expressed in all Expressed in all liver: 186.7 Expressed in all +STK40 MGC4796, SgK495 ENSG00000196182 Serine/threonine kinase 40 1 36339624-36385896 Enzymes, Predicted membrane proteins Evidence at protein level HPA008026 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:5.59e-4 (favourable) Expressed in all Expressed in all testis: 57.0 Expressed in all +OR10J1 HGMP07J, HSHGMP07J ENSG00000196184 Olfactory receptor family 10 subfamily J member 1 1 159439722-159440811 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 102 testis: 10.2 all non-specific tissues: 0.0 Not detected +TMEM63A KIAA0792 ENSG00000196187 Transmembrane protein 63A 1 225845536-225882369 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066504, HPA066936, HPA068918 Enhanced Vesicles
Microtubule organizing center Endometrial cancer:8.79e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 77.2 Mixed +CTSE ENSG00000196188 Cathepsin E 1 206009264-206023909 Enzymes, Predicted secreted proteins Evidence at protein level HPA012940, CAB032687 Enhanced Urothelial cancer:5.26e-5 (favourable) Group enriched Group enriched 9 duodenum: 229.1;stomach: 1121.8 lung: 74.6 Group enriched 7 BEWO: 20.3;RT4: 32.6 +SEMA4A CORD10, FLJ12287, SEMAB, SemB ENSG00000196189 Semaphorin 4A 1 156147366-156177752 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA053726, HPA066006, HPA069136 Supported Enhanced Nucleus Head and neck cancer:1.09e-4 (favourable), Renal cancer:8.20e-4 (unfavourable) Expressed in all Mixed epididymis: 62.3 Cell line enhanced Karpas-707: 108.3;U-698: 46.5 +HRCT1 LGLL338, PRO537, UNQ338 ENSG00000196196 Histidine rich carboxyl terminus 1 9 35906192-35907141 Predicted intracellular proteins Evidence at transcript level HPA067038 Approved Nucleoplasm Liver cancer:3.62e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 17.9 colon: 13.2 Cell line enhanced EFO-21: 16.8;HeLa: 10.0;U-2197: 24.6;U-251 MG: 10.6 +MPHOSPH8 HSMPP8, mpp8 ENSG00000196199 M-phase phosphoprotein 8 13 19633681-19673459 Predicted intracellular proteins Evidence at protein level HPA039701, HPA040035 Enhanced Supported Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all ovary: 63.5 Expressed in all +GREB1 KIAA0575 ENSG00000196208 Growth regulation by estrogen in breast cancer 1 2 11482341-11642788 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024616, HPA027843, HPA028416 Uncertain Approved Mitochondria
Cytosol Endometrial cancer:1.05e-4 (favourable) Tissue enhanced Tissue enhanced ovary: 156.8 prostate: 57.1 Cell line enhanced AF22: 39.6;MCF7: 47.1;SH-SY5Y: 42.6;T-47d: 129.7 +SIRPB2 dJ776F14.2, PTPN1L, PTPNS1L3 ENSG00000196209 Signal regulatory protein beta 2 20 1470741-1491587 Predicted membrane proteins Evidence at protein level HPA011548, HPA048032 Uncertain Approved Nuclear bodies Mixed Tissue enhanced appendix: 17.0 placenta: 10.9 Cell line enhanced A-431: 4.2;HMC-1: 7.0;hTCEpi: 6.2;THP-1: 5.3;U-937: 6.6 +ZNF766 ENSG00000196214 Zinc finger protein 766 19 52269571-52296046 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044882, HPA063496 Uncertain Supported Centrosome Expressed in all Expressed in all testis: 43.6 Expressed in all +RYR1 CCO, MHS, MHS1, PPP1R137, RYR ENSG00000196218 Ryanodine receptor 1 19 38433699-38587564 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA056416 Enhanced Approved Golgi apparatus
Vesicles
Cytosol Mixed Tissue enriched 31 skeletal muscle: 572.4 esophagus: 18.6 Cell line enhanced HaCaT: 16.8;RH-30: 14.8;SiHa: 32.7;U-2 OS: 13.2 +SRGAP3 ARHGAP14, KIAA0411, MEGAP, SRGAP2, WRP ENSG00000196220 SLIT-ROBO Rho GTPase activating protein 3 3 8980591-9363053 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036959, HPA044074 Enhanced Approved Nucleoplasm Mixed Tissue enhanced cerebral cortex: 26.5;fallopian tube: 17.4 cervix, uterine: 7.9 Cell line enhanced AF22: 8.9;HBEC3-KT: 5.7;RT4: 8.6;T-47d: 9.6 +KRTAP5-3 KRTAP5-9, KRTAP5.3 ENSG00000196224 Keratin associated protein 5-3 11 1607565-1608463 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +FAM217B C20orf177, dJ551D2.5 ENSG00000196227 Family with sequence similarity 217 member B 20 59933764-59948680 Predicted intracellular proteins Evidence at protein level HPA041021, HPA056698 Approved Supported Nucleoplasm Expressed in all Mixed cerebral cortex: 34.9 Expressed in all +SULT1C3 ENSG00000196228 Sulfotransferase family 1C member 3 2 108247195-108265351 Enzymes, Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 142 breast: 450.3 duodenum: 3.1 Not detected +TUBB M40, MGC16435, OK/SW-cl.56, Tubb5 ENSG00000196230 Tubulin beta class I 6 30720201-30725426 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005417, CAB012406, HPA043640, HPA046280 Enhanced Supported Microtubules Renal cancer:2.62e-8 (unfavourable), Liver cancer:5.97e-4 (unfavourable) Expressed in all Expressed in all ovary: 72.3 Mixed +LCOR C10orf12, DKFZP564P1916, FLJ13022, FLJ38026, KIAA1795, MLR2 ENSG00000196233 Ligand dependent nuclear receptor corepressor 10 96832260-96995959 Predicted intracellular proteins Evidence at protein level HPA031428, HPA031429, HPA038954, HPA057621, HPA077000 Uncertain Enhanced Nucleoplasm Urothelial cancer:2.16e-4 (favourable) Expressed in all Expressed in all bone marrow: 19.2 Expressed in all +SUPT5H FLJ34157, SPT5, SPT5H ENSG00000196235 SPT5 homolog, DSIF elongation factor subunit 19 39436156-39476670 Predicted intracellular proteins Evidence at protein level HPA029273, CAB034370 Enhanced Enhanced Nucleoplasm Liver cancer:7.00e-5 (unfavourable) Expressed in all Expressed in all testis: 169.6 Expressed in all +XPNPEP3 APP3, ICP55, NPHPL1 ENSG00000196236 X-prolyl aminopeptidase 3 22 40857077-40932815 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000527 Enhanced Thyroid cancer:6.10e-4 (unfavourable), Breast cancer:8.19e-4 (unfavourable) Expressed in all Mixed duodenum: 14.5 Mixed +OR2T2 OR2T2P ENSG00000196240 Olfactory receptor family 2 subfamily T member 2 1 248452798-248453772 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR2C3 OR2C4, OR2C5P, OST742 ENSG00000196242 Olfactory receptor family 2 subfamily C member 3 1 247530132-247533839 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA053920, HPA058578 Uncertain Enhanced Plasma membrane Not detected Expressed in all parathyroid gland: 27.0 Expressed in all +ZNF107 smap-7, ZFD25, ZNF588 ENSG00000196247 Zinc finger protein 107 7 64666083-64711582 Predicted intracellular proteins, Transcription factors Evidence at transcript level Renal cancer:2.62e-4 (unfavourable) Expressed in all Mixed lymph node: 19.4 Expressed in all +OR10S1 ENSG00000196248 Olfactory receptor family 10 subfamily S member 1 11 123976661-123977781 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA019038 Uncertain Not detected Not detected thyroid gland: 0.1 Not detected +SFTA2 SFTPG ENSG00000196260 Surfactant associated 2 6 30931353-30955636 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Pancreatic cancer:1.26e-4 (unfavourable) Tissue enhanced Tissue enriched 10 lung: 53.8 esophagus: 5.2 Group enriched 5 CACO-2: 7.9;CAPAN-2: 4.5 +PPIA CYPA ENSG00000196262 Peptidylprolyl isomerase A 7 44796680-44824564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004655, HPA058345 Uncertain Liver cancer:2.27e-6 (unfavourable) Expressed in all Expressed in all breast: 1679.8 Expressed in all +ZNF471 KIAA1396, Z1971 ENSG00000196263 Zinc finger protein 471 19 56507843-56530221 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA066695 Uncertain Supported Nucleus Renal cancer:2.37e-4 (favourable) Mixed Mixed ovary: 27.4 Mixed +OR10J3 OR10J3P ENSG00000196266 Olfactory receptor family 10 subfamily J member 3 1 159313670-159314659 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA042963 Uncertain Not detected Not detected placenta: 0.6 Cell line enriched 7 LHCN-M2: 1.1 +ZNF836 FLJ16287 ENSG00000196267 Zinc finger protein 836 19 52153864-52171643 Predicted intracellular proteins, Transcription factors Evidence at transcript level Renal cancer:3.77e-4 (favourable), Cervical cancer:5.11e-4 (favourable) Expressed in all Mixed adrenal gland: 34.6 Mixed +ZNF493 FLJ36504 ENSG00000196268 Zinc finger protein 493 19 21397119-21427573 Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Expressed in all thyroid gland: 34.6 Mixed +GTF2IRD2 FLJ37938, GTF2IRD2A ENSG00000196275 GTF2I repeat domain containing 2 7 74796144-74851551 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056679, HPA056680 Approved Nucleoplasm Mixed Expressed in all ovary: 16.2 Cell line enhanced SK-BR-3: 44.5 +GRM7 GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87 ENSG00000196277 Glutamate metabotropic receptor 7 3 6770001-7741533 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015964 Uncertain Cytosol Not detected Tissue enhanced cerebral cortex: 10.1;parathyroid gland: 7.2 smooth muscle: 3.4 Cell line enriched 12 SH-SY5Y: 5.0 +SUPT3H SPT3, SPT3L ENSG00000196284 SPT3 homolog, SAGA and STAGA complex component 6 44809317-45377953 Predicted intracellular proteins Evidence at protein level HPA024371 Enhanced Supported Nucleoplasm Ovarian cancer:1.72e-4 (favourable), Glioma:3.05e-4 (favourable) Expressed in all Mixed testis: 14.5 Mixed +BECN2 BECN1P1 ENSG00000196289 Beclin 2 1 241957767-241959062 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +NIF3L1 ALS2CR1, CALS-7, MDS015 ENSG00000196290 NGG1 interacting factor 3 like 1 2 200889327-200903930 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036335, HPA036336, HPA061466 Enhanced Approved Vesicles Liver cancer:2.51e-6 (unfavourable), Endometrial cancer:9.52e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 40.6 Expressed in all +ATP2A1 ATP2A, SERCA1 ENSG00000196296 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 16 28878405-28904509 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002310, CAB032706 Enhanced Approved Endoplasmic reticulum Tissue enhanced Tissue enriched 96 skeletal muscle: 2781.9 esophagus: 29.1 Mixed +IARS IARS1, ILRS ENSG00000196305 Isoleucyl-tRNA synthetase 9 92210207-92293756 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029806 Approved Supported Cytosol Liver cancer:4.98e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 141.8 Expressed in all +MFSD14C HIATL2, MGC12945 ENSG00000196312 Major facilitator superfamily domain containing 14C 9 96897917-97013708 Predicted membrane proteins Evidence at transcript level Expressed in all Mixed testis: 13.9 Cell line enhanced HAP1: 27.3 +POM121 DKFZP586G1822, DKFZP586P2220, KIAA0618, POM121A ENSG00000196313 POM121 transmembrane nucleoporin 7 72879365-72951440 Predicted intracellular proteins, Transporters Evidence at protein level CAB003710, HPA043809, HPA049817 Approved Enhanced Nucleoplasm
Nuclear membrane Expressed in all Expressed in all cerebral cortex: 30.2 Expressed in all +ZBTB44 BTBD15, HSPC063, ZNF851 ENSG00000196323 Zinc finger and BTB domain containing 44 11 130226677-130314686 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052589 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 75.4 Expressed in all +GIMAP5 HIMAP3, IAN4L1, IAN5 ENSG00000196329 GTPase, IMAP family member 5 7 150722253-150750033 Predicted membrane proteins Evidence at protein level Mixed Expressed in all lymph node: 80.5 Cell line enhanced HDLM-2: 3.4;MOLT-4: 23.3;U-937: 5.3 +STK31 SgK396, TDRD8 ENSG00000196335 Serine/threonine kinase 31 7 23710167-23832513 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023194 Enhanced Mixed Tissue enriched 197 testis: 112.9 lung: 0.5 Cell line enriched 7 CACO-2: 15.0 +CGB7 CG-beta-a ENSG00000196337 Chorionic gonadotropin beta subunit 7 19 49054275-49058860 Predicted secreted proteins Evidence at protein level HPA038925, HPA038934 Supported Approved Cytosol Not detected Tissue enhanced skin: 3.8 placenta,seminal vesicle,skeletal muscle: 1.0 Cell line enhanced BEWO: 4.7;HaCaT: 3.5;hTCEpi: 3.4;U-251 MG: 6.1 +NLGN3 ASPGX1, AUTSX1, HNL3, KIAA1480 ENSG00000196338 Neuroligin 3 X 71144831-71171201 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003183, HPA004066 Enhanced Supported Golgi apparatus
Cell Junctions Tissue enriched Tissue enhanced cerebral cortex: 62.2 seminal vesicle: 17.3 Cell line enhanced AF22: 6.8;NTERA-2: 5.0;SH-SY5Y: 2.9 +OR8D1 OR8D3, OST004 ENSG00000196341 Olfactory receptor family 8 subfamily D member 1 11 124309812-124310837 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA059510 Uncertain Not detected Tissue enriched 13 testis: 1.3 all non-specific tissues: 0.0 Not detected +ADH7 ADH-4 ENSG00000196344 Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 4 99412261-99435737 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039695 Enhanced Supported Plasma membrane
Cytosol Group enriched Tissue enriched 6 esophagus: 215.5 tonsil: 34.5 Cell line enhanced HaCaT: 1.0 +ZKSCAN7 FLJ12738, ZNF167, ZNF448, ZNF64, ZSCAN39 ENSG00000196345 Zinc finger with KRAB and SCAN domains 7 3 44555193-44594173 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048312, HPA049906, HPA071850 Uncertain Enhanced Cytosol Mixed Mixed ovary: 4.1 Cell line enhanced AN3-CA: 3.9;SH-SY5Y: 5.2 +ZNF729 ENSG00000196350 Zinc finger protein 729 19 22286408-22317176 Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enriched Tissue enriched 22 testis: 3.8 breast,cerebral cortex,endometrium,parathyroid gland: 0.1 Cell line enhanced NTERA-2: 2.6 +CD55 CR, CROM, DAF, TC ENSG00000196352 CD55 molecule (Cromer blood group) 1 207321508-207386804 Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA002190, CAB010454, HPA024386 Enhanced Uncertain Vesicles
Midbody ring Renal cancer:9.36e-4 (unfavourable) Expressed in all Expressed in all lung: 324.4 Cell line enhanced HMC-1: 495.0;U-2197: 364.6 +CPNE4 COPN4, CPN4 ENSG00000196353 Copine 4 3 131533555-132285410 Predicted intracellular proteins Evidence at protein level HPA032036, HPA078300 Enhanced Approved Nucleoplasm
Cytosol Tissue enriched Tissue enhanced cerebral cortex: 12.1;prostate: 40.8 seminal vesicle: 5.8 Cell line enhanced A549: 5.6;AF22: 5.6 +ZNF565 FLJ36991 ENSG00000196357 Zinc finger protein 565 19 36182060-36246257 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044123 Uncertain Approved Nucleoplasm
Nuclear bodies Expressed in all Mixed testis: 11.6 Mixed +NTNG2 KIAA1857, Lmnt2, NTNG1 ENSG00000196358 Netrin G2 9 132161676-132244534 Predicted secreted proteins Evidence at protein level HPA061242, HPA065089, HPA071290 Approved Approved Nucleus
Nucleoli
Plasma membrane
Cytokinetic bridge
Midbody ring
Cytosol Prostate cancer:6.06e-4 (favourable) Mixed Group enriched 6 bone marrow: 26.5;cerebral cortex: 18.5;parathyroid gland: 16.3;prostate: 10.0 spleen: 3.1 Cell line enhanced HMC-1: 14.1;NB-4: 24.3;U-937: 7.7 +ELAVL3 DKFZp547J036, HUC, HUCL, MGC20653, PLE21 ENSG00000196361 ELAV like RNA binding protein 3 19 11451326-11481046 Predicted intracellular proteins Evidence at protein level CAB013066 Enhanced Tissue enriched Tissue enriched 45 cerebral cortex: 72.8 adrenal gland: 1.6 Group enriched 10 SCLC-21H: 95.2;SH-SY5Y: 49.4 +WDR5 CFAP89, SWD3 ENSG00000196363 WD repeat domain 5 9 134135365-134159968 Predicted intracellular proteins Evidence at protein level HPA047182 Supported Nucleoplasm Expressed in all Expressed in all testis: 63.0 Expressed in all +LONP1 hLON, LonHS, PIM1, PRSS15 ENSG00000196365 Lon peptidase 1, mitochondrial 19 5691834-5720572 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002034, HPA002192 Supported Enhanced Nucleus
Mitochondria Expressed in all Expressed in all adrenal gland: 140.4 Expressed in all +TRRAP PAF400, TR-AP, Tra1 ENSG00000196367 Transformation/transcription domain associated protein 7 98877933-99013243 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054376 Supported Nucleoplasm
Golgi apparatus Liver cancer:8.77e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.6 Expressed in all +NUDT11 DIPP3b, FLJ10628, hDIPP3beta ENSG00000196368 Nudix hydrolase 11 X 51490011-51496596 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047027, HPA057684 Approved Approved Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 40.1;testis: 67.7 prostate,seminal vesicle: 14.7 Cell line enhanced HAP1: 71.2;NTERA-2: 42.7 +SRGAP2B SRGAP2P2 ENSG00000196369 SLIT-ROBO Rho GTPase activating protein 2B 1 144887265-145095528 Predicted intracellular proteins Evidence at transcript level Mixed Mixed skin: 21.7 Expressed in all +FUT4 CD15, ELFT, FCT3A, FUC-TIV ENSG00000196371 Fucosyltransferase 4 11 94543840-94549898 Predicted membrane proteins Evidence at protein level CAB000014, CAB016129 Enhanced Enhanced Vesicles Lung cancer:3.64e-4 (unfavourable) Expressed in all Tissue enriched 5 bone marrow: 62.9 duodenum: 12.4 Cell line enhanced HL-60: 29.6;THP-1: 31.3;U-937: 25.8 +ASB13 FLJ13134, MGC19879 ENSG00000196372 Ankyrin repeat and SOCS box containing 13 10 5638867-5666595 Predicted intracellular proteins Evidence at protein level HPA048293, HPA061742 Approved Approved Nucleus
Golgi apparatus Expressed in all Expressed in all small intestine: 28.0 Mixed +SLC35F1 C6orf169, dJ230I3.1 ENSG00000196376 Solute carrier family 35 member F1 6 117907526-118317676 Predicted membrane proteins, Transporters Evidence at protein level HPA019576 Enhanced Approved Nucleoplasm
Microtubule organizing center
Cytosol Group enriched Tissue enriched 12 cerebral cortex: 45.4 epididymis: 3.7 Group enriched 10 AF22: 47.2;WM-115: 80.1 +ZNF34 KOX32 ENSG00000196378 Zinc finger protein 34 8 144773114-144787345 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA053925, HPA060755, HPA066805 Uncertain Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all ovary: 12.8 Mixed +ZNF781 FLJ37549 ENSG00000196381 Zinc finger protein 781 19 37667751-37692322 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062512 Uncertain Approved Nucleoplasm Mixed Mixed smooth muscle: 3.7 Cell line enhanced AN3-CA: 2.1;SH-SY5Y: 2.4;U-266/84: 2.0 +ZNF140 pHZ-39 ENSG00000196387 Zinc finger protein 140 12 133079838-133107544 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048332 Uncertain Expressed in all Expressed in all thyroid gland: 16.3 Mixed +INCA1 ENSG00000196388 Inhibitor of CDK, cyclin A1 interacting protein 1 17 4988130-4997610 Predicted intracellular proteins Evidence at protein level HPA044359, HPA052401 Uncertain Approved Nucleoplasm
Nuclear bodies Pancreatic cancer:3.61e-5 (favourable) Expressed in all Tissue enhanced testis: 54.0 thyroid gland: 13.4 Mixed +ZNF774 MGC75360 ENSG00000196391 Zinc finger protein 774 15 90352245-90369146 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030839, HPA030840 Uncertain Supported Intermediate filaments
Cytosol Mixed Mixed cerebral cortex: 8.1 Mixed +PTPN1 PTP1B ENSG00000196396 Protein tyrosine phosphatase, non-receptor type 1 20 50510321-50585241 Enzymes, Predicted membrane proteins Evidence at protein level CAB009329, HPA012542, CAB015217 Enhanced Enhanced Endoplasmic reticulum Expressed in all Expressed in all parathyroid gland: 62.6 Expressed in all +EVL RNB6 ENSG00000196405 Enah/Vasp-like 14 99971449-100144236 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018849, HPA019536, CAB033987 Enhanced Approved Vesicles
Cytosol Pancreatic cancer:4.07e-6 (favourable), Renal cancer:4.14e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 208.1 Cell line enhanced MOLT-4: 229.2 +SPANXD CT11.4, SPANXE ENSG00000196406 SPANX family member D X 141697411-141698739 Predicted intracellular proteins Evidence at protein level HPA046423, HPA073647 Supported Approved Nucleoplasm
Vesicles Not detected Tissue enriched 193 testis: 19.3 all non-specific tissues: 0.0 Group enriched 10 A-431: 2.2;U-2 OS: 4.8 +THEM5 FLJ37964 ENSG00000196407 Thioesterase superfamily member 5 1 151847263-151853697 Enzymes, Predicted intracellular proteins Evidence at protein level Expressed in all Tissue enriched 25 skin: 204.8 cerebral cortex: 8.3 Cell line enriched 6 HDLM-2: 64.7 +NOXO1 P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28 ENSG00000196408 NADPH oxidase organizer 1 16 1978917-1984192 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA071540 Enhanced Not detected Tissue enhanced appendix: 6.3;colon: 7.4;rectum: 6.5 duodenum: 3.3 Cell line enhanced CAPAN-2: 2.4;HaCaT: 1.4;SCLC-21H: 1.6 +EPHB4 HTK, Tyro11 ENSG00000196411 EPH receptor B4 7 100802565-100827521 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB013537 Uncertain Colorectal cancer:4.33e-4 (unfavourable), Breast cancer:8.56e-4 (unfavourable), Urothelial cancer:8.84e-4 (unfavourable) Expressed in all Expressed in all placenta: 50.6 Mixed +PRTN3 ACPA, AGP7, C-ANCA, MBT, P29, PR-3 ENSG00000196415 Proteinase 3 19 840960-848175 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005938, CAB017558 Enhanced Tissue enhanced Tissue enriched 724 bone marrow: 616.4 spleen: 0.8 Cell line enriched 6 THP-1: 696.6 +ZNF765 ENSG00000196417 Zinc finger protein 765 19 53389793-53430413 Predicted intracellular proteins, Transcription factors Evidence at protein level Breast cancer:9.11e-4 (unfavourable) Mixed Mixed parathyroid gland: 13.0 Mixed +ZNF124 HZF-16, HZF16 ENSG00000196418 Zinc finger protein 124 1 247121975-247172016 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031127 Uncertain Approved Nucleus
Nuclear membrane Urothelial cancer:1.03e-4 (favourable) Expressed in all Mixed salivary gland: 16.8 Mixed +XRCC6 D22S671, D22S731, G22P1, KU70, ML8 ENSG00000196419 X-ray repair cross complementing 6 22 41621119-41664048 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004254, HPA047549, HPA062226 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all testis: 396.5 Expressed in all +S100A5 S100D ENSG00000196420 S100 calcium binding protein A5 1 153537147-153541765 Predicted intracellular proteins Evidence at protein level HPA064184 Approved Nucleoplasm Group enriched Tissue enhanced skin: 4.3;thyroid gland: 8.8 lymph node: 1.7 Cell line enhanced RT4: 15.9;SCLC-21H: 20.4 +LINC00176 DKFZp434G015, FLJ27267, NCRNA00176, PRR17 ENSG00000196421 Long intergenic non-protein coding RNA 176 20 64034344-64039962 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Tissue enriched Not detected parathyroid gland,spleen: 0.2 Group enriched 11 HDLM-2: 6.9;Hep G2: 33.0 +PPP1R26 KIAA0649 ENSG00000196422 Protein phosphatase 1 regulatory subunit 26 9 135479079-135488893 Predicted intracellular proteins Evidence at protein level HPA044686, HPA063817 Uncertain Enhanced Nucleoplasm Renal cancer:6.20e-13 (favourable), Colorectal cancer:3.98e-4 (unfavourable), Pancreatic cancer:6.93e-4 (favourable), Endometrial cancer:9.91e-4 (favourable) Expressed in all Mixed parathyroid gland: 27.6 Mixed +NBPF4 FLJ32833 ENSG00000196427 Neuroblastoma breakpoint family member 4 1 108223341-108244081 Predicted intracellular proteins Evidence at transcript level HPA045044, HPA046411, HPA047447, HPA058050 Uncertain Tissue enriched Tissue enhanced testis: 7.1 small intestine: 1.5 Cell line enhanced BEWO: 6.8;K-562: 9.7;MCF7: 9.6 +TSC22D2 KIAA0669, TILZ4a, TILZ4b, TILZ4c ENSG00000196428 TSC22 domain family member 2 3 150408335-150466431 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004926 Approved Approved Cytosol Endometrial cancer:2.74e-4 (unfavourable), Renal cancer:5.80e-4 (unfavourable) Expressed in all Expressed in all endometrium,smooth muscle: 38.2 Expressed in all +CRYBA4 ENSG00000196431 Crystallin beta A4 22 26621964-26630672 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA071178 Supported Tissue enhanced Tissue enhanced epididymis: 1.8 testis: 0.7 Group enriched 7 HEL: 6.5;HMC-1: 1.4 +ASMT ASMTY, HIOMT, HIOMTY ENSG00000196433 Acetylserotonin O-methyltransferase X 1615001-1643081 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced epididymis: 2.2 adrenal gland: 0.8 Not detected +NPIPB15 LOC440348, NPIPL2 ENSG00000196436 Nuclear pore complex interacting protein family member B15 16 74377878-74392080 Predicted membrane proteins Evidence at protein level HPA011188, HPA053611 Supported Approved Nucleoplasm Expressed in all Tissue enhanced testis: 39.2 rectum: 13.2 Cell line enhanced T-47d: 11.2 +ZNF569 FLJ32053, ZAP1 ENSG00000196437 Zinc finger protein 569 19 37411155-37469275 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052994 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Mixed Mixed testis: 20.5 Mixed +ARMCX4 CXorf35, GASP4, MGC40053 ENSG00000196440 Armadillo repeat containing, X-linked 4 X 101418287-101533459 Predicted intracellular proteins Evidence at protein level HPA000429, HPA051930 Uncertain Approved Nucleoplasm
Vesicles Pancreatic cancer:8.20e-5 (favourable) Mixed Mixed parathyroid gland: 14.3 Mixed +YRDC FLJ23476, IRIP, SUA5 ENSG00000196449 YrdC N6-threonylcarbamoyltransferase domain containing 1 37802944-37808185 Predicted intracellular proteins Evidence at protein level HPA030147 Approved Approved Mitochondria Liver cancer:1.83e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 31.7 Expressed in all +ZNF777 KIAA1285 ENSG00000196453 Zinc finger protein 777 7 149431363-149461123 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003252 Approved Approved Nucleus Expressed in all Expressed in all cerebral cortex: 10.4 Mixed +PIK3R4 p150, VPS15 ENSG00000196455 Phosphoinositide-3-kinase regulatory subunit 4 3 130678935-130746829 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036032, HPA036033 Approved Approved Vesicles
Microtubules Renal cancer:4.40e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 46.6 Expressed in all +ZNF775 MGC33584 ENSG00000196456 Zinc finger protein 775 7 150379335-150398631 Predicted intracellular proteins, Transcription factors Evidence at transcript level Pancreatic cancer:1.35e-5 (favourable), Renal cancer:2.84e-4 (favourable), Head and neck cancer:3.48e-4 (favourable) Expressed in all Mixed cerebral cortex: 7.1 Mixed +ZNF605 ENSG00000196458 Zinc finger protein 605 12 132918308-132956306 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA061970, HPA062655 Uncertain Approved Nucleoplasm
Vesicles Expressed in all Mixed parathyroid gland: 11.3 Mixed +TRAPPC2 hYP38334, MIP-2A, SEDL, SEDT, TRS20, ZNF547L ENSG00000196459 Trafficking protein particle complex 2 X 13712244-13734635 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004665, HPA063308 Approved Approved Nucleoplasm
Endoplasmic reticulum
Vesicles Urothelial cancer:7.89e-5 (favourable), Ovarian cancer:6.35e-4 (favourable), Cervical cancer:8.09e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 16.5 Expressed in all +RFX8 FLJ42986 ENSG00000196460 RFX family member 8, lacking RFX DNA binding domain 2 101397361-101474703 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059745 Approved Nucleoplasm
Nuclear bodies Mixed Tissue enhanced bone marrow: 2.6 testis: 1.3 Cell line enhanced hTEC/SVTERT24-B: 13.4;LHCN-M2: 5.8;U-87 MG: 8.3 +MYL6B MLC1SA ENSG00000196465 Myosin light chain 6B 12 56152256-56159647 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038887, HPA046859, HPA063034 Enhanced Approved Vesicles Liver cancer:2.87e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 149.6 Expressed in all +ZNF799 HIT-40, MGC71805, ZNF842 ENSG00000196466 Zinc finger protein 799 19 12390016-12401271 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003150, HPA018683 Supported Uncertain Nucleoplasm
Microtubule organizing center Endometrial cancer:2.39e-4 (favourable) Mixed Mixed placenta: 6.9 Mixed +FGF16 MF4 ENSG00000196468 Fibroblast growth factor 16 X 77447405-77457278 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Not detected Not detected adipose tissue: 0.4 Cell line enriched 5 U-2197: 21.1 +SIAH1 hSIAH1 ENSG00000196470 Siah E3 ubiquitin protein ligase 1 16 48356364-48448402 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018724 Enhanced Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all placenta: 70.4 Expressed in all +GK2 GKP2, GKTA ENSG00000196475 Glycerol kinase 2 4 79406352-79408293 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA060687 Uncertain Not detected Tissue enriched 1527 testis: 152.6 all non-specific tissues: 0.0 Cell line enriched 45 SCLC-21H: 4.4 +C20orf96 dJ1103G7.2 ENSG00000196476 Chromosome 20 open reading frame 96 20 270863-290778 Predicted intracellular proteins Evidence at transcript level HPA048649 Uncertain Approved Nucleus
Golgi apparatus Pancreatic cancer:4.12e-5 (favourable), Liver cancer:6.12e-5 (unfavourable), Urothelial cancer:1.05e-4 (favourable) Expressed in all Expressed in all fallopian tube: 53.5 Mixed +ESRRG NR3B3 ENSG00000196482 Estrogen related receptor gamma 1 216503246-217137755 FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044678 Uncertain Approved Nucleus Renal cancer:1.13e-11 (favourable) Mixed Tissue enhanced parathyroid gland: 77.5 kidney: 31.3 Group enriched 7 RPMI-8226: 16.0;SCLC-21H: 9.4;SH-SY5Y: 44.7 +IPO4 FLJ23338, Imp4 ENSG00000196497 Importin 4 14 24180219-24188964 Predicted intracellular proteins, Transporters Evidence at protein level HPA039043, HPA064572 Uncertain Approved Cytosol Liver cancer:8.08e-6 (unfavourable), Renal cancer:3.20e-4 (unfavourable) Expressed in all Tissue enhanced testis: 17.4 skin: 5.3 Mixed +NCOR2 CTG26, SMRT, SMRTE, TNRC14, TRAC-1 ENSG00000196498 Nuclear receptor corepressor 2 12 124324415-124567589 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001928 Approved Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 81.2 Expressed in all +SULT1A1 P-PST, STP, STP1 ENSG00000196502 Sulfotransferase family 1A member 1 16 28605196-28623625 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049500, HPA051051 Supported Lung cancer:7.02e-4 (favourable) Expressed in all Expressed in all duodenum: 136.6 Cell line enhanced EFO-21: 161.0;Hep G2: 241.3 +ARL9 ENSG00000196503 ADP ribosylation factor like GTPase 9 4 56505209-56524448 Predicted intracellular proteins Evidence at protein level HPA072942 Enhanced Approved Nucleoli
Mitochondria Mixed Tissue enhanced testis: 18.3 smooth muscle: 4.3 Group enriched 5 REH: 14.6;SCLC-21H: 15.6 +PRPF40A FBP-11, FBP11, FLAF1, FLJ20585, FNBP3, HIP10, HYPA, NY-REN-6, Prp40 ENSG00000196504 Pre-mRNA processing factor 40 homolog A 2 152651593-152717997 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038272, HPA038273 Approved Enhanced Nuclear speckles Pancreatic cancer:1.58e-5 (unfavourable), Liver cancer:1.68e-4 (unfavourable), Renal cancer:5.89e-4 (unfavourable) Expressed in all Expressed in all testis: 50.1 Expressed in all +GDAP2 dJ776P7.1, FLJ20142, MACROD3 ENSG00000196505 Ganglioside induced differentiation associated protein 2 1 117863485-117929630 Predicted intracellular proteins Evidence at protein level HPA046185 Approved Approved Endoplasmic reticulum Expressed in all Mixed parathyroid gland: 9.5 Expressed in all +TCEAL3 MGC15737, WEX8 ENSG00000196507 Transcription elongation factor A like 3 X 103607451-103629690 Predicted intracellular proteins Evidence at protein level HPA045564, HPA058982 Uncertain Lung cancer:4.05e-4 (favourable), Ovarian cancer:8.33e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 97.9 Mixed +ANAPC7 APC7 ENSG00000196510 Anaphase promoting complex subunit 7 12 110372900-110403730 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009567 Approved Approved Nucleoplasm
Cytosol Renal cancer:4.36e-10 (unfavourable), Liver cancer:1.54e-6 (unfavourable) Expressed in all Expressed in all testis: 48.9 Expressed in all +TPK1 HTPK1, PP20 ENSG00000196511 Thiamin pyrophosphokinase 1 7 144451941-144836395 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA021545, HPA021849 Approved Approved Vesicles Mixed Mixed duodenum: 14.4 Cell line enhanced AN3-CA: 65.0;EFO-21: 19.9 +SLC6A9 GLYT1 ENSG00000196517 Solute carrier family 6 member 9 1 43991500-44031467 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA013977 Uncertain Approved Nucleus
Golgi apparatus Renal cancer:5.93e-4 (unfavourable), Endometrial cancer:9.50e-4 (unfavourable) Expressed in all Tissue enhanced skin: 49.7 adrenal gland: 30.8 Cell line enhanced hTCEpi: 77.6 +AFAP1 AFAP, AFAP-110 ENSG00000196526 Actin filament associated protein 1 4 7758714-7939926 Predicted intracellular proteins Evidence at protein level HPA015642, CAB024712 Enhanced Supported Actin filaments
Focal adhesion sites
Cytosol Lung cancer:2.84e-4 (unfavourable), Renal cancer:8.18e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 42.9 Cell line enhanced TIME: 103.1 +NACA NACA1 ENSG00000196531 Nascent polypeptide-associated complex alpha subunit 12 56712428-56731628 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA073152, HPA073648 Approved Cytosol Renal cancer:4.58e-11 (unfavourable) Expressed in all Expressed in all ovary: 2552.0 Expressed in all +MYO18A KIAA0216, MysPDZ ENSG00000196535 Myosin XVIIIA 17 29071124-29180412 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019646, HPA021121 Enhanced Renal cancer:3.18e-4 (favourable), Ovarian cancer:3.28e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 133.5 Expressed in all +OR2T3 ENSG00000196539 Olfactory receptor family 2 subfamily T member 3 1 248473351-248474307 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +SPTSSB ADMP, C3orf57, ssSPTb ENSG00000196542 Serine palmitoyltransferase small subunit B 3 161344792-161372880 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047712 Approved Nuclear speckles Tissue enhanced Tissue enhanced skin: 48.3;stomach: 59.4;urinary bladder: 36.3 prostate: 23.4 Group enriched 9 MCF7: 892.8;RT4: 244.7 +BORCS6 C17orf59, FLJ20014 ENSG00000196544 BLOC-1 related complex subunit 6 17 8188333-8190907 Predicted intracellular proteins Evidence at protein level HPA045415, HPA060791 Uncertain Supported Centrosome
Cytosol Pancreatic cancer:2.60e-4 (favourable), Endometrial cancer:2.78e-4 (favourable) Expressed in all Mixed spleen: 7.3 Expressed in all +MAN2A2 HsT19662, MANA2X ENSG00000196547 Mannosidase alpha class 2A member 2 15 90902218-90922584 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017226, HPA077930 Approved Approved Cytoplasmic bodies Renal cancer:8.95e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 46.3 Expressed in all +MME CALLA, CD10, NEP ENSG00000196549 Membrane metalloendopeptidase 3 155024124-155183729 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000013, HPA052583, HPA056072 Enhanced Mixed Tissue enhanced duodenum: 428.2;kidney: 384.2;small intestine: 401.5 prostate: 162.5 Cell line enhanced ASC TERT1: 595.9;BJ hTERT+: 1084.7;HSkMC: 604.7 +FAM72A LMPIP, MGC57827, RP11-312O7.1, UGENE ENSG00000196550 Family with sequence similarity 72 member A 1 206186179-206204414 Predicted intracellular proteins Evidence at protein level HPA043271, HPA067321 Uncertain Approved Vesicles
Plasma membrane
Cytosol Mixed Mixed lymph node: 12.6 Expressed in all +LINC00238 C14orf53, NCRNA00238 ENSG00000196553 Long intergenic non-protein coding RNA 238 14 66486354-66498553 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 85 testis: 8.5 all non-specific tissues: 0.0 Not detected +CACNA1H Cav3.2 ENSG00000196557 Calcium voltage-gated channel subunit alpha1 H 16 1153121-1221772 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA039125 Approved Approved Nucleoplasm
Vesicles Renal cancer:1.78e-5 (unfavourable), Pancreatic cancer:3.12e-5 (favourable) Expressed in all Tissue enhanced ovary: 44.9 seminal vesicle: 39.1 Cell line enhanced A549: 16.1;AN3-CA: 23.5;MCF7: 36.8;T-47d: 13.0 +SULF2 HSULF-2, KIAA1247, SULF-2 ENSG00000196562 Sulfatase 2 20 47656348-47786616 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002325 Approved Cervical cancer:6.43e-5 (unfavourable), Renal cancer:4.02e-4 (unfavourable) Expressed in all Expressed in all endometrium: 166.9 Cell line enhanced EFO-21: 318.0;hTCEpi: 589.4;MCF7: 529.8 +HBG2 HBG-T1 ENSG00000196565 Hemoglobin subunit gamma 2 11 5253190-5645789 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016143, HPA043234 Approved Approved Vesicles Not detected Tissue enriched 147 placenta: 18253.8 bone marrow: 124.0 Group enriched 301 HEL: 12101.5;K-562: 8442.3 +LAMA2 LAMM ENSG00000196569 Laminin subunit alpha 2 6 128883141-129516569 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB040310, CAB078182 Enhanced Urothelial cancer:3.65e-5 (unfavourable) Expressed in all Tissue enhanced placenta: 150.0 ovary: 49.5 Cell line enhanced ASC diff: 174.0;ASC TERT1: 126.8;HSkMC: 113.6 +PFN3 ENSG00000196570 Profilin 3 5 177400107-177400636 Predicted intracellular proteins Evidence at protein level Not detected Group enriched 21 kidney: 1.0;testis: 3.2 all non-specific tissues: 0.0 Not detected +PLXNB2 KIAA0315, MM1, PLEXB2 ENSG00000196576 Plexin B2 22 50274979-50307627 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003100 Uncertain Stomach cancer:4.75e-4 (favourable), Ovarian cancer:7.37e-4 (unfavourable) Expressed in all Expressed in all spleen: 120.9 Mixed +OR5AC2 HSA1 ENSG00000196578 Olfactory receptor family 5 subfamily AC member 2 3 98087173-98088102 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.4 Not detected +AJAP1 MOT8, SHREW-1, SHREW1 ENSG00000196581 Adherens junctions associated protein 1 1 4654732-4792534 Predicted membrane proteins Evidence at protein level Renal cancer:1.89e-7 (favourable) Mixed Tissue enhanced cerebral cortex: 11.3;ovary: 6.0 kidney,seminal vesicle: 3.2 Cell line enhanced BEWO: 7.2;EFO-21: 6.2;RPTEC TERT1: 18.3 +XRCC2 FANCU ENSG00000196584 X-ray repair cross complementing 2 7 152644779-152676165 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065153 Approved Nucleoplasm
Vesicles Mixed Mixed testis: 3.7 Mixed +MYO6 DFNA22, DFNB37, KIAA0389 ENSG00000196586 Myosin VI 6 75749192-75919537 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010762, HPA035483 Enhanced Renal cancer:1.27e-12 (favourable) Expressed in all Mixed parathyroid gland: 85.5 Mixed +MKL1 BSAC, KIAA1438, MAL, MRTF-A ENSG00000196588 Megakaryoblastic leukemia (translocation) 1 22 40410281-40636702 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030782 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.58e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 51.3 Expressed in all +CTB-25J19.1 ENSG00000196589 19 7018969-7021450 Predicted intracellular proteins No evidence HPA051259 Uncertain Not detected Not detected testis: 0.3 Not detected +HDAC2 RPD3, YAF1 ENSG00000196591 Histone deacetylase 2 6 113933028-114011308 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005054, HPA011727 Supported Enhanced Nucleus Liver cancer:5.39e-10 (unfavourable), Breast cancer:7.07e-4 (unfavourable) Expressed in all Expressed in all testis: 141.1 Expressed in all +ZNF782 FLJ16636 ENSG00000196597 Zinc finger protein 782 9 96816472-96875623 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA011013 Approved Approved Nucleus
Mitochondria Expressed in all Mixed testis: 10.4 Mixed +SLC22A25 HIMTP, MGC120420, UST6 ENSG00000196600 Solute carrier family 22 member 25 11 63163776-63229652 Predicted membrane proteins, Transporters Evidence at transcript level HPA039390 Uncertain Liver cancer:7.04e-4 (favourable) Tissue enriched Tissue enriched 58 liver: 5.7 all non-specific tissues: 0.0 Not detected +POTEF A26C1B, POTE2alpha, POTEACTIN ENSG00000196604 POTE ankyrin domain family member F 2 130074030-130129222 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA041264, HPA041271, HPA042822, HPA043260 Uncertain Not detected Tissue enriched 9 testis: 2.7 breast,placenta,prostate: 0.2 Cell line enhanced AN3-CA: 2.3;BEWO: 1.9;CACO-2: 1.9;U-2 OS: 5.6;U-266/70: 2.0 +ZNF846 ENSG00000196605 Zinc finger protein 846 19 9751993-9793180 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034617, HPA034618 Approved Approved Actin filaments Head and neck cancer:5.25e-8 (favourable) Expressed in all Mixed seminal vesicle: 26.3 Mixed +MMP1 CLG ENSG00000196611 Matrix metallopeptidase 1 11 102789920-102798160 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA004920 Approved Vesicles Renal cancer:9.86e-10 (unfavourable), Liver cancer:4.22e-6 (unfavourable), Cervical cancer:4.66e-4 (unfavourable) Tissue enhanced Tissue enhanced appendix: 39.2;gallbladder: 126.4 urinary bladder: 29.1 Cell line enhanced BJ hTERT+: 921.1;HBF TERT88: 1061.5;HUVEC TERT2: 2464.5;WM-115: 1436.5 +ADH1B ADH2 ENSG00000196616 Alcohol dehydrogenase 1B (class I), beta polypeptide 4 99304964-99352760 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047814, HPA060902 Supported Approved Plasma membrane
Cytosol Renal cancer:7.87e-4 (unfavourable) Tissue enriched Group enriched 6 adipose tissue: 1624.6;liver: 3000.2 lung: 388.5 Cell line enriched 7 ASC diff: 4511.9 +UGT2B15 UGT2B8 ENSG00000196620 UDP glucuronosyltransferase family 2 member B15 4 68646630-68670628 Enzymes, Predicted membrane proteins Evidence at protein level HPA045108 Approved Urothelial cancer:4.50e-4 (favourable), Liver cancer:9.82e-4 (favourable) Tissue enriched Group enriched 5 gallbladder: 110.7;liver: 107.6 small intestine: 20.6 Not detected +TCF4 bHLHb19, E2-2, ITF2, SEF2-1B ENSG00000196628 Transcription factor 4 18 55222331-55664787 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB020722, HPA025958 Approved Supported Nucleoplasm
Cytosol Renal cancer:7.24e-5 (unfavourable), Urothelial cancer:9.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex,cervix, uterine: 44.9 Cell line enhanced HDLM-2: 128.1;SH-SY5Y: 177.9 +WNK3 PRKWNK3 ENSG00000196632 WNK lysine deficient protein kinase 3 X 54192823-54358642 Enzymes, Predicted intracellular proteins Evidence at protein level HPA077678 Approved Vesicles Mixed Group enriched 6 epididymis: 14.3;testis: 18.6 ovary: 2.6 Cell line enhanced AF22: 4.4;HAP1: 5.4;NTERA-2: 9.1;SiHa: 4.8;U-2 OS: 4.1 +SDHAF3 ACN9, DC11, LYRM10, Sdh7 ENSG00000196636 Succinate dehydrogenase complex assembly factor 3 7 97116590-97181763 Predicted intracellular proteins Evidence at protein level HPA020523 Approved Approved Microtubules
Mitochondria Expressed in all Expressed in all testis: 15.1 Mixed +HRH1 ENSG00000196639 Histamine receptor H1 3 11137093-11263557 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029740 Uncertain Supported Plasma membrane
Cytosol Pancreatic cancer:1.27e-5 (unfavourable) Mixed Mixed cerebral cortex: 12.4 Mixed +RABL6 bA216L13.9, C9orf86, FLJ10101, FLJ13045, Parf, pp8875, RBEL1 ENSG00000196642 RAB, member RAS oncogene family-like 6 9 136807943-136841187 Predicted intracellular proteins Evidence at protein level HPA044037 Uncertain Supported Centrosome
Cytosol Pancreatic cancer:1.46e-4 (favourable), Endometrial cancer:4.00e-4 (favourable), Stomach cancer:9.14e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 59.7 Expressed in all +ZNF136 pHZ-20 ENSG00000196646 Zinc finger protein 136 19 12163064-12189881 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054120 Approved Nucleoli Renal cancer:4.75e-5 (favourable) Expressed in all Mixed thyroid gland: 14.5 Mixed +ZKSCAN5 ZFP95, ZNF914, ZSCAN37 ENSG00000196652 Zinc finger with KRAB and SCAN domains 5 7 99504651-99534700 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003201 Uncertain Approved Intermediate filaments Liver cancer:7.59e-6 (unfavourable), Thyroid cancer:1.13e-4 (unfavourable) Expressed in all Mixed testis: 15.1 Expressed in all +ZNF502 FLJ12515, FLJ14855 ENSG00000196653 Zinc finger protein 502 3 44712643-44723831 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024761, HPA029557 Uncertain Renal cancer:4.51e-5 (favourable), Urothelial cancer:2.06e-4 (favourable) Expressed in all Mixed testis: 5.0 Mixed +TRAPPC4 PTD009, SBDN, TRS23 ENSG00000196655 Trafficking protein particle complex 4 11 119018432-119025454 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039752, HPA041371 Approved Approved Cytosol Liver cancer:2.03e-5 (unfavourable) Expressed in all Expressed in all testis: 15.0 Expressed in all +TTC30B fleer, FLJ30990, IFT70B ENSG00000196659 Tetratricopeptide repeat domain 30B 2 177548998-177553014 Predicted intracellular proteins Evidence at protein level HPA051714, HPA052100, HPA052487 Supported Approved Nucleus
Centrosome Expressed in all Mixed fallopian tube: 15.6 Mixed +SLC30A10 DKFZp547M236, ZnT-10, ZNT8, ZRC1 ENSG00000196660 Solute carrier family 30 member 10 1 219685427-219958647 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA064547 Enhanced Tissue enriched Tissue enhanced duodenum: 2.1;liver: 2.3 testis: 1.2 Cell line enhanced HEK 293: 1.2 +OR8B3 ENSG00000196661 Olfactory receptor family 8 subfamily B member 3 11 124396382-124397368 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.5 Not detected +TECPR2 KIAA0329 ENSG00000196663 Tectonin beta-propeller repeat containing 2 14 102362963-102502481 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000658 Enhanced Approved Nucleus Renal cancer:6.53e-9 (favourable), Liver cancer:5.66e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 21.4 Mixed +TLR7 ENSG00000196664 Toll like receptor 7 X 12867083-12890380 FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA059613 Enhanced Mixed Mixed placenta: 9.2 Group enriched 5 Daudi: 11.6;U-266/70: 12.4 +FAM180B LOC399888 ENSG00000196666 Family with sequence similarity 180 member B 11 47586693-47589194 Predicted intracellular proteins Evidence at transcript level HPA029408 Uncertain Tissue enhanced Tissue enhanced breast: 6.9;skin: 4.4 adipose tissue: 4.1 Cell line enhanced SK-MEL-30: 1.8;U-937: 1.3 +ZFP62 FLJ34231, ZET, ZNF755 ENSG00000196670 ZFP62 zinc finger protein 5 180847611-180861285 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048629 Approved Approved Nucleoplasm
Actin filaments Expressed in all Expressed in all thyroid gland: 39.6 Expressed in all +ERI2 EXOD1, KIAA1504, MGC16943, ZGRF5 ENSG00000196678 ERI1 exoribonuclease family member 2 16 20780193-20900349 Predicted intracellular proteins Evidence at protein level HPA035384, HPA035385 Uncertain Supported Nucleus
Golgi apparatus Expressed in all Expressed in all testis: 23.0 Expressed in all +TOMM7 Tom7 ENSG00000196683 Translocase of outer mitochondrial membrane 7 7 22812628-22822852 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Head and neck cancer:6.30e-4 (unfavourable) Expressed in all Expressed in all ovary: 677.6 Expressed in all +HSH2D ALX, FLJ14886, HSH2 ENSG00000196684 Hematopoietic SH2 domain containing 19 16134028-16158575 Predicted intracellular proteins Evidence at protein level HPA036616 Approved Plasma membrane
Focal adhesion sites
Cytosol Renal cancer:6.49e-6 (unfavourable), Colorectal cancer:9.46e-6 (unfavourable), Urothelial cancer:3.47e-5 (favourable) Mixed Mixed tonsil: 32.7 Cell line enhanced HMC-1: 49.9;NB-4: 88.6;RPMI-8226: 43.5;U-937: 106.3 +TRPV1 VR1 ENSG00000196689 Transient receptor potential cation channel subfamily V member 1 17 3565444-3609411 FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Not detected Mixed duodenum: 7.8 Mixed +ZNF33B KOX2, KOX31, ZNF11B ENSG00000196693 Zinc finger protein 33B 10 42574185-42638568 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056638 Approved Expressed in all Expressed in all parathyroid gland: 32.1 Mixed +ZNF512B GM632, MGC149845, MGC149846 ENSG00000196700 Zinc finger protein 512B 20 63956702-63969865 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006688 Approved Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex,parathyroid gland: 16.9 Mixed +AMZ2 ENSG00000196704 Archaelysin family metallopeptidase 2 17 68247574-68257164 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023299, HPA052406 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:1.32e-5 (unfavourable), Renal cancer:3.14e-4 (unfavourable) Expressed in all Expressed in all testis: 357.6 Expressed in all +ZNF431 KIAA1969 ENSG00000196705 Zinc finger protein 431 19 21142024-21196053 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059135 Uncertain Mixed Mixed ovary: 26.8 Mixed +ALKAL1 AUGB, FAM150A, UNQ9433 ENSG00000196711 ALK and LTK ligand 1 8 52534037-52565507 Predicted secreted proteins Evidence at protein level HPA027368 Uncertain Mixed Tissue enhanced gallbladder: 3.5;thyroid gland: 3.6 cervix, uterine: 1.7 Cell line enhanced CAPAN-2: 1.1 +NF1 ENSG00000196712 Neurofibromin 1 17 31094927-31382116 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level HPA045502 Uncertain Approved Mitochondria Expressed in all Expressed in all parathyroid gland: 33.0 Expressed in all +VKORC1L1 ENSG00000196715 Vitamin K epoxide reductase complex subunit 1 like 1 7 65873267-65959563 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA053954 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all adipose tissue: 57.5 Expressed in all +ZNF418 FLJ31551, KIAA1956 ENSG00000196724 Zinc finger protein 418 19 57921884-57935393 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043800, HPA053762, HPA072145 Approved Uncertain Nucleus Prostate cancer:1.72e-4 (unfavourable) Mixed Mixed parathyroid gland: 14.8 Cell line enhanced AF22: 11.0 +DAPK1 DAPK ENSG00000196730 Death associated protein kinase 1 9 87497228-87708633 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level CAB037302, HPA040472, HPA048436 Approved Approved Centrosome Colorectal cancer:2.48e-5 (unfavourable) Expressed in all Mixed lung: 56.3 Cell line enhanced HMC-1: 85.8 +LCE1B LEP2, SPRL2A ENSG00000196734 Late cornified envelope 1B 1 152811971-152813109 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 9 skin: 186.0 breast: 20.1 Cell line enhanced hTCEpi: 1.4 +HLA-DQA1 CELIAC1, HLA-DQA ENSG00000196735 Major histocompatibility complex, class II, DQ alpha 1 6 32628179-32647062 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012315 Enhanced Expressed in all Tissue enhanced lung: 504.8 lymph node: 338.6 Cell line enriched 9 HDLM-2: 1315.9 +COL27A1 FLJ11895, KIAA1870, MGC11337 ENSG00000196739 Collagen type XXVII alpha 1 chain 9 114155560-114312511 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021884, HPA048471 Uncertain Expressed in all Mixed endometrium: 39.8 Cell line enhanced BEWO: 53.2;Hep G2: 33.0 +GM2A SAP-3 ENSG00000196743 GM2 ganglioside activator 5 151212150-151270440 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008063 Enhanced Liver cancer:1.77e-5 (unfavourable) Expressed in all Expressed in all skin: 89.5 Expressed in all +HIST1H2AI H2A/c, H2AFC ENSG00000196747 Histone cluster 1 H2A family member i 6 27808199-27808701 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Mixed Mixed bone marrow: 3.1 Cell line enhanced K-562: 37.5;U-266/84: 81.3 +CLPSL2 C6orf126, dJ510O8.5, UNQ3045 ENSG00000196748 Colipase like 2 6 35776594-35779552 Predicted secreted proteins Evidence at protein level HPA043460, HPA051655 Approved Uncertain Vesicles Tissue enhanced Tissue enriched 703 epididymis: 713.1 seminal vesicle: 1.0 Cell line enriched 6 T-47d: 6.6 +S100A2 CAN19, S100L ENSG00000196754 S100 calcium binding protein A2 1 153561108-153567890 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB002600, CAB047340, HPA062451 Enhanced Supported Nucleus
Nucleoli
Plasma membrane
Cytosol Pancreatic cancer:2.04e-4 (unfavourable) Expressed in all Tissue enhanced esophagus: 1481.8 tonsil: 368.4 Cell line enhanced HBEC3-KT: 15305.5;RT4: 6706.3 +ZNF700 DKFZp434I1610 ENSG00000196757 Zinc finger protein 700 19 11925068-11950773 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA047845 Uncertain Uncertain Nucleus Renal cancer:2.01e-5 (unfavourable), Urothelial cancer:2.53e-5 (favourable), Head and neck cancer:1.27e-4 (favourable), Prostate cancer:1.75e-4 (unfavourable), Melanoma:2.58e-4 (unfavourable) Expressed in all Expressed in all skin: 19.1 Mixed +POU3F4 BRN4, DFN3, DFNX2, OTF9 ENSG00000196767 POU class 3 homeobox 4 X 83508250-83512127 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031984, HPA062295 Uncertain Supported Nucleus Tissue enriched Tissue enriched 11 cerebral cortex: 7.9 kidney: 0.7 Cell line enriched 96 AF22: 9.6 +OR14A16 OR5AT1 ENSG00000196772 Olfactory receptor family 14 subfamily A member 16 1 247814800-247815729 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.1 Not detected +CD47 IAP, MER6, OA3 ENSG00000196776 CD47 molecule 3 108043298-108091025 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB016055, HPA044659 Approved Supported Golgi apparatus
Vesicles
Plasma membrane Thyroid cancer:7.29e-5 (favourable), Renal cancer:1.69e-4 (unfavourable), Endometrial cancer:2.44e-4 (unfavourable) Expressed in all Expressed in all lung: 204.6 Expressed in all +OR52K1 ENSG00000196778 Olfactory receptor family 52 subfamily K member 1 11 4488879-4489908 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected appendix: 0.1 Not detected +TLE1 ESG, ESG1, GRG1 ENSG00000196781 Transducin like enhancer of split 1 9 81583683-81689305 Predicted intracellular proteins Evidence at protein level CAB011482, HPA071396 Supported Supported Nucleoplasm Thyroid cancer:7.60e-4 (unfavourable), Renal cancer:8.07e-4 (favourable) Expressed in all Expressed in all endometrium: 51.2 Mixed +MAML3 CAGH3, GDN, KIAA1816, MAM2, TNRC3 ENSG00000196782 Mastermind like transcriptional coactivator 3 4 139716753-140154184 Predicted intracellular proteins Evidence at protein level HPA037717 Approved Supported Nuclear speckles Renal cancer:7.60e-5 (favourable) Expressed in all Mixed endometrium: 10.8 Cell line enhanced SCLC-21H: 18.5;SH-SY5Y: 25.4;WM-115: 20.0 +HIST1H2AG H2A.1b, H2A/p, H2AFP, pH2A/f ENSG00000196787 Histone cluster 1 H2A family member g 6 27133042-27135291 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Expressed in all Tissue enhanced testis: 5.5 breast: 3.7 Cell line enhanced SiHa: 18.4;U-266/84: 34.4 +STRN3 PPP2R6B, S/G2NA, SG2NA ENSG00000196792 Striatin 3 14 30893799-31026401 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003392, HPA004636, CAB069925 Approved Supported Nucleoplasm
Actin filaments
Cytosol Renal cancer:9.66e-4 (favourable) Expressed in all Expressed in all testis: 44.5 Expressed in all +ZNF239 HOK-2, MOK2 ENSG00000196793 Zinc finger protein 239 10 43556344-43574618 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030843, HPA046679 Uncertain Approved Nucleus
Nuclear bodies Renal cancer:4.70e-7 (unfavourable) Expressed in all Mixed testis: 14.7 Cell line enhanced NTERA-2: 24.4 +SPINK14 SPINK5L2 ENSG00000196800 Serine peptidase inhibitor, Kazal type 14 (putative) 5 148169733-148175398 Predicted secreted proteins Evidence at transcript level Not detected Tissue enhanced breast: 1.1;rectum: 1.2 cervix, uterine: 0.7 Not detected +SPRR2B ENSG00000196805 Small proline rich protein 2B 1 153070224-153070840 Predicted intracellular proteins Evidence at transcript level Tissue enriched Group enriched 18 esophagus: 30.3;skin: 17.1;testis: 8.2;tonsil: 14.1 ovary: 0.9 Not detected +CHRNG ACHRG ENSG00000196811 Cholinergic receptor nicotinic gamma subunit 2 232539727-232546403 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Tissue enhanced Tissue enriched 17 skeletal muscle: 8.2 prostate: 0.4 Group enriched 21 HSkMC: 2.3;RH-30: 8.7 +ZSCAN16 dJ265C24.3, FLJ22191, ZNF392, ZNF435 ENSG00000196812 Zinc finger and SCAN domain containing 16 6 28124560-28130082 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007290 Supported Approved Nucleus Ovarian cancer:1.14e-5 (favourable), Urothelial cancer:3.41e-5 (favourable), Lung cancer:3.19e-4 (favourable), Cervical cancer:5.73e-4 (favourable) Expressed in all Mixed parathyroid gland: 12.6 Mixed +MVB12B C9orf28, FAM125B, FLJ00001 ENSG00000196814 Multivesicular body subunit 12B 9 126326849-126507041 Predicted intracellular proteins Evidence at protein level HPA043683, HPA049383 Uncertain Approved Golgi apparatus
Vesicles Pancreatic cancer:7.89e-4 (favourable) Expressed in all Mixed cerebral cortex: 36.5 Cell line enhanced AF22: 34.2 +C6orf106 dJ391O22.4, FLJ22195 ENSG00000196821 Chromosome 6 open reading frame 106 6 34587288-34696859 Predicted intracellular proteins Evidence at protein level HPA034489, HPA034490 Approved Approved Nuclear speckles Expressed in all Expressed in all testis: 125.7 Expressed in all +CTD-2192J16.17 ENSG00000196826 19 12461559-12551474 Predicted intracellular proteins No evidence Not detected Not detected endometrium: 0.7 Not detected +OR11G2 ENSG00000196832 Olfactory receptor family 11 subfamily G member 2 14 20197336-20198446 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 19 HEL: 1.9 +POTEI POTE2beta ENSG00000196834 POTE ankyrin domain family member I 2 130459455-130509666 Predicted intracellular proteins Evidence at protein level HPA041264, HPA041271, HPA042822, HPA043260 Uncertain Not detected Group enriched 16 prostate: 17.4;testis: 10.3 breast: 0.8 Cell line enhanced AN3-CA: 2.5;BEWO: 3.2;K-562: 3.0;U-2 OS: 7.5 +ADA ENSG00000196839 Adenosine deaminase 20 44619522-44652233 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001399, CAB004307, HPA023884 Enhanced Supported Plasma membrane
Cytosol Renal cancer:2.94e-14 (unfavourable), Endometrial cancer:1.23e-7 (unfavourable), Liver cancer:6.77e-5 (unfavourable), Lung cancer:2.20e-4 (unfavourable) Expressed in all Tissue enriched 13 duodenum: 487.7 lymph node: 36.5 Cell line enriched 9 MOLT-4: 1479.5 +ARID5A MRF-1, RP11-363D14 ENSG00000196843 AT-rich interaction domain 5A 2 96536743-96552638 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002860, HPA023879 Approved Supported Nucleus
Nucleoli Renal cancer:4.24e-8 (unfavourable), Breast cancer:2.05e-6 (favourable) Expressed in all Expressed in all appendix: 25.4 Group enriched 6 HDLM-2: 239.9;RPMI-8226: 78.9 +PATE2 C11orf38, LVLF3112, PATE-M, UNQ3112 ENSG00000196844 Prostate and testis expressed 2 11 125776113-125778819 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 11 epididymis: 550.7 seminal vesicle: 50.7 Not detected +PPTC7 TA-PP2C ENSG00000196850 PTC7 protein phosphatase homolog 12 110533245-110583320 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039335, HPA040614 Approved Approved Plasma membrane
Cytosol Ovarian cancer:1.43e-5 (unfavourable), Renal cancer:4.48e-5 (favourable), Pancreatic cancer:6.76e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.4 Expressed in all +KRT39 KA35 ENSG00000196859 Keratin 39 17 40958417-40966892 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +TOMM20L UNQ9438 ENSG00000196860 Translocase of outer mitochondrial membrane 20 like 14 58395916-58408701 Predicted membrane proteins Evidence at transcript level HPA044997 Uncertain Mixed Tissue enriched 11 testis: 13.1 epididymis: 1.2 Cell line enhanced SCLC-21H: 1.1 +RGPD4 DKFZp686P0288, RGP4 ENSG00000196862 RANBP2-like and GRIP domain containing 4 2 107826937-107890841 Predicted intracellular proteins Evidence at transcript level HPA049497, HPA051675, HPA067564 Uncertain Uncertain Nuclear membrane
Vesicles Not detected Tissue enriched 57 testis: 5.7 all non-specific tissues: 0.0 Not detected +NHLRC2 DKFZp779F115, FLJ20147, FLJ25621, FLJ33312, MGC45492 ENSG00000196865 NHL repeat containing 2 10 113854661-113917194 Predicted intracellular proteins Evidence at protein level HPA038493, HPA057564 Approved Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 18.6 Expressed in all +HIST1H2AD H2A.3, H2A/g, H2AFG ENSG00000196866 Histone cluster 1 H2A family member d 6 26198851-26199243 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Mixed Tissue enhanced bone marrow: 2.2;prostate: 1.9 esophagus: 1.2 Cell line enhanced U-266/70: 15.6;U-266/84: 5.0 +ZFP28 KIAA1431, mkr5 ENSG00000196867 ZFP28 zinc finger protein 19 56538948-56556810 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028879 Uncertain Approved Nucleoplasm
Cytosol Mixed Mixed ovary: 13.0 Mixed +KIAA1211L C2orf55, MGC42367 ENSG00000196872 KIAA1211 like 2 98793846-98936259 Predicted intracellular proteins Evidence at protein level HPA051082, HPA061678 Uncertain Approved Microtubules
Cytokinetic bridge
Centrosome Renal cancer:1.13e-5 (favourable), Thyroid cancer:1.33e-5 (favourable) Expressed in all Tissue enhanced cerebral cortex: 36.7;epididymis: 38.2 fallopian tube: 36.1 Cell line enhanced BEWO: 39.4;HDLM-2: 56.9 +CBWD3 bA561O23.1 ENSG00000196873 COBW domain containing 3 9 68232003-68300015 Predicted intracellular proteins Evidence at transcript level HPA042759, HPA042813 Uncertain Approved Plasma membrane Not detected Expressed in all appendix: 25.1 Expressed in all +SCN8A CerIII, MED, NaCh6, Nav1.6, PN4 ENSG00000196876 Sodium voltage-gated channel alpha subunit 8 12 51590266-51812864 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Mixed Tissue enriched 7 cerebral cortex: 22.1 testis: 3.1 Mixed +LAMB3 BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa ENSG00000196878 Laminin subunit beta 3 1 209614870-209652466 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008069, CAB078183 Enhanced Approved Nucleoli
Mitochondria Renal cancer:2.43e-5 (unfavourable), Lung cancer:9.62e-5 (unfavourable), Pancreatic cancer:2.55e-4 (unfavourable), Breast cancer:8.43e-4 (favourable) Expressed in all Mixed stomach: 68.9 Cell line enhanced CAPAN-2: 308.4;HaCaT: 470.9;HBEC3-KT: 935.2;hTCEpi: 295.3 +HIST3H2BB ENSG00000196890 Histone cluster 3 H2B family member b 1 228458107-228460470 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed Tissue enhanced fallopian tube: 2.2 adrenal gland,skin: 1.3 Cell line enhanced T-47d: 5.9;U-266/70: 23.3;U-266/84: 5.4 +TEX43 C5orf48, FLJ27505, MGC163367, MGC163369, Tseg7 ENSG00000196900 Testis expressed 43 5 126631722-126636287 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 62 testis: 35.7 colon: 0.5 Not detected +KPNA5 IPOA6, SRP6 ENSG00000196911 Karyopherin subunit alpha 5 6 116681187-116741866 Predicted intracellular proteins, Transporters Evidence at protein level CAB026464, HPA054037 Enhanced Supported Cytosol Expressed in all Tissue enhanced testis: 78.5 ovary: 22.1 Expressed in all +ANKRD36B FLJ21281, KIAA1641 ENSG00000196912 Ankyrin repeat domain 36B 2 97492663-97589965 Predicted intracellular proteins Evidence at protein level HPA051757, HPA057661 Approved Nucleus
Cytosol Mixed Mixed testis: 12.2 Mixed +ARHGEF12 KIAA0382, LARG ENSG00000196914 Rho guanine nucleotide exchange factor 12 11 120336914-120489936 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018911, CAB025581 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:5.43e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 145.8 Mixed +HCAR1 FKSG80, GPR104, GPR81, HCA1, LACR1, TA-GPCR ENSG00000196917 Hydroxycarboxylic acid receptor 1 12 122726076-122730843 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Breast cancer:3.61e-5 (unfavourable) Mixed Tissue enriched 8 parathyroid gland: 115.0 breast: 15.1 Cell line enhanced CAPAN-2: 10.9;MCF7: 6.3;RT4: 28.4 +PDLIM7 ENIGMA ENSG00000196923 PDZ and LIM domain 7 5 177483394-177497606 Predicted intracellular proteins Evidence at protein level HPA018794, HPA048815 Approved Enhanced Actin filaments
Focal adhesion sites Renal cancer:6.19e-10 (unfavourable), Lung cancer:4.07e-4 (unfavourable), Endometrial cancer:5.45e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 288.9 Expressed in all +FLNA ABP-280, FLN, FLN1, OPD1, OPD2 ENSG00000196924 Filamin A X 154348524-154374638 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level CAB000356, HPA000368, HPA001016, HPA001115, HPA002925 Enhanced Approved Enhanced Plasma membrane
Actin filaments
Cytosol Renal cancer:1.54e-6 (unfavourable), Urothelial cancer:3.88e-4 (unfavourable), Colorectal cancer:7.37e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 1051.0 Expressed in all +TMEM26 Em:AC068892.1, MGC35010 ENSG00000196932 Transmembrane protein 26 10 61406643-61453450 Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced spleen: 11.8 endometrium: 6.8 Cell line enhanced BJ hTERT+: 3.7;HSkMC: 1.4;HUVEC TERT2: 1.2;MOLT-4: 1.8 +SRGAP1 ARHGAP13, KIAA1304 ENSG00000196935 SLIT-ROBO Rho GTPase activating protein 1 12 63844293-64162221 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA052416 Uncertain Approved Nuclear speckles Ovarian cancer:5.67e-4 (unfavourable) Mixed Mixed parathyroid gland: 13.1 Cell line enhanced hTERT-HME1: 36.0 +FAM3C GS3876, ILEI ENSG00000196937 Family with sequence similarity 3 member C 7 121348851-121396364 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043376, HPA050548 Enhanced Enhanced Golgi apparatus Expressed in all Expressed in all thyroid gland: 181.1 Expressed in all +NOP9 C14orf21 ENSG00000196943 NOP9 nucleolar protein 14 24299862-24309124 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000850 Approved Nucleus
Nucleoli
Cytosol Renal cancer:9.39e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 28.9 Expressed in all +OR2T4 OR2T4Q ENSG00000196944 Olfactory receptor family 2 subfamily T member 4 1 248361581-248362627 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected cervix, uterine,prostate: 0.1 Not detected +ZNF705A FLJ16353 ENSG00000196946 Zinc finger protein 705A 12 8157034-8188537 Predicted intracellular proteins, Transcription factors Evidence at transcript level Not detected Mixed cerebral cortex: 8.9 Cell line enhanced AN3-CA: 5.3;BJ hTERT+: 5.5;HDLM-2: 5.4;NTERA-2: 6.4 +SLC39A10 DKFZp564L2123, FLJ90515, KIAA1265 ENSG00000196950 Solute carrier family 39 member 10 2 195575977-195737702 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA036512, HPA036513, HPA066087 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Glioma:2.05e-5 (favourable), Liver cancer:4.39e-5 (unfavourable), Pancreatic cancer:3.23e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 77.7;thyroid gland: 79.2 prostate: 30.8 Expressed in all +CASP4 ICE(rel)II, ICH-2, TX ENSG00000196954 Caspase 4 11 104942866-104969436 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA027588, CAB037167 Approved Approved Plasma membrane
Cytosol Renal cancer:3.27e-11 (unfavourable) Expressed in all Expressed in all placenta: 71.8 Mixed +AP2A1 ADTAA, CLAPA1 ENSG00000196961 Adaptor related protein complex 2 alpha 1 subunit 19 49766968-49807113 Predicted intracellular proteins Evidence at protein level CAB004306 Approved Supported Vesicles Renal cancer:2.83e-9 (unfavourable), Ovarian cancer:2.91e-4 (unfavourable) Expressed in all Expressed in all testis: 103.9 Expressed in all +ZNF585A FLJ23765 ENSG00000196967 Zinc finger protein 585A 19 37106734-37172741 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Expressed in all thyroid gland: 17.9 Mixed +FUT11 MGC33202 ENSG00000196968 Fucosyltransferase 11 10 73772291-73780251 Predicted secreted proteins Evidence at protein level HPA014033 Approved Approved Nuclear membrane
Golgi apparatus Cervical cancer:2.39e-6 (unfavourable), Renal cancer:3.67e-4 (unfavourable), Breast cancer:6.78e-4 (unfavourable) Expressed in all Mixed placenta: 25.0 Mixed +SMIM10L2B LINC00087, NCRNA00087, RP11-85L21.2 ENSG00000196972 Small integral membrane protein 10 like 2B X 135094987-135098634 Predicted membrane proteins Evidence at transcript level Renal cancer:2.41e-5 (favourable) Mixed Tissue enhanced cerebral cortex: 23.9 parathyroid gland: 7.4 Cell line enhanced HHSteC: 1.6;HSkMC: 2.2;NTERA-2: 1.6 +ANXA4 ANX4 ENSG00000196975 Annexin A4 2 69644425-69827100 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB005076, HPA007393, CAB017560 Approved Approved Cytosol Ovarian cancer:2.38e-4 (unfavourable), Renal cancer:6.05e-4 (unfavourable), Breast cancer:8.55e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 881.8 Cell line enhanced EFO-21: 386.6;RPTEC TERT1: 457.3 +LAGE3 CVG5, DXS9879E, DXS9951E, ESO3, ITBA2, Pcc1 ENSG00000196976 L antigen family member 3 X 154477769-154479257 Predicted intracellular proteins Evidence at protein level HPA036122, HPA036123 Approved Supported Nucleoplasm
Nuclear bodies Cervical cancer:5.29e-6 (favourable), Renal cancer:5.42e-5 (unfavourable), Liver cancer:8.63e-5 (unfavourable), Endometrial cancer:7.60e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 26.9 Expressed in all +WDR5B FLJ11287 ENSG00000196981 WD repeat domain 5B 3 122412332-122416051 Predicted intracellular proteins Evidence at transcript level HPA042994 Approved Expressed in all Mixed epididymis: 13.3 Mixed +FAM163B C9orf166 ENSG00000196990 Family with sequence similarity 163 member B 9 133578415-133586197 Predicted membrane proteins Evidence at transcript level HPA067336 Approved Approved Nuclear bodies
Plasma membrane
Cytosol Tissue enriched Tissue enriched 6 cerebral cortex: 103.5 adrenal gland: 16.4 Cell line enriched 19 SH-SY5Y: 72.4 +NPIPB9 ENSG00000196993 Nuclear pore complex interacting protein family member B9 16 28751787-28772807 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011188, HPA053611 Approved Approved Nucleoplasm Not detected Tissue enriched 8 testis: 14.5 skin: 1.9 Cell line enhanced hTCEpi: 3.1 +WDR45 JM5, NBIA5, WDRX1, WIPI4 ENSG00000196998 WD repeat domain 45 X 49071470-49101170 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027562 Uncertain Approved Nucleoli Cervical cancer:1.21e-4 (favourable), Head and neck cancer:1.61e-4 (favourable) Expressed in all Expressed in all epididymis: 258.8 Expressed in all +METTL9 DREV1 ENSG00000197006 Methyltransferase like 9 16 21597218-21657473 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053588, HPA056347 Uncertain Approved Nucleus
Cell Junctions
Cytosol Liver cancer:8.71e-4 (unfavourable) Expressed in all Expressed in all kidney: 92.0 Expressed in all +ZNF138 pHZ-32 ENSG00000197008 Zinc finger protein 138 7 64794388-64833681 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA077435 Uncertain Cytosol Expressed in all Mixed cerebral cortex: 9.1 Expressed in all +ZNF429 ENSG00000197013 Zinc finger protein 429 19 21496682-21556270 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004139 Approved Nucleus Ovarian cancer:1.96e-8 (favourable), Pancreatic cancer:7.30e-4 (favourable) Mixed Mixed thyroid gland: 16.3 Mixed +ZNF470 CZF-1, FLJ26175 ENSG00000197016 Zinc finger protein 470 19 56567511-56588911 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029000 Uncertain Supported Nucleoplasm
Nuclear bodies Mixed Mixed cerebral cortex,testis: 5.8 Cell line enhanced HEK 293: 10.0 +SERTAD1 SEI1, TRIP-Br1 ENSG00000197019 SERTA domain containing 1 19 40421592-40426025 Predicted intracellular proteins Evidence at protein level HPA063323 Approved Nucleoplasm
Golgi apparatus Expressed in all Expressed in all gallbladder: 19.6 Mixed +ZNF100 ENSG00000197020 Zinc finger protein 100 19 21722766-21767628 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059135 Uncertain Urothelial cancer:5.47e-4 (favourable) Mixed Mixed testis: 11.6 Cell line enhanced MOLT-4: 24.6 +CXorf40B ENSG00000197021 Chromosome X open reading frame 40B X 149929527-149938811 Predicted intracellular proteins Evidence at transcript level HPA060897 Approved Thyroid cancer:1.02e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 78.6 Expressed in all +ZNF398 KIAA1339, P51, P71, ZER6 ENSG00000197024 Zinc finger protein 398 7 149126416-149182802 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071533 Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all testis: 16.1 Expressed in all +ZSCAN25 FLJ32468, ZNF498 ENSG00000197037 Zinc finger and SCAN domain containing 25 7 99616946-99632407 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055127, HPA057173 Uncertain Approved Nucleus
Nucleoli fibrillar center Expressed in all Mixed parathyroid gland: 10.0 Expressed in all +ANXA6 ANX6 ENSG00000197043 Annexin A6 5 151100712-151157882 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA002462, CAB005077, HPA009650 Enhanced Renal cancer:1.31e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 431.9 Mixed +ZNF441 FLJ38637 ENSG00000197044 Zinc finger protein 441 19 11767000-11784078 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA063338 Approved Nuclear speckles Expressed in all Mixed thyroid gland: 12.1 Mixed +GMFB GMF ENSG00000197045 Glia maturation factor beta 14 54474484-54489196 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002954 Approved Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:9.48e-5 (favourable), Liver cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 108.7 Expressed in all +SIGLEC15 CD33L3, HsT1361 ENSG00000197046 Sialic acid binding Ig like lectin 15 18 45825512-45844080 Predicted membrane proteins Evidence at protein level HPA053509 Supported Nucleoplasm
Golgi apparatus Urothelial cancer:9.14e-5 (favourable) Mixed Not detected spleen: 0.6 Group enriched 8 PC-3: 9.6;U-87 MG: 30.2 +ZNF420 FLJ32191 ENSG00000197050 Zinc finger protein 420 19 37007857-37130314 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059675 Approved Approved Nucleoplasm Glioma:4.88e-5 (favourable), Renal cancer:1.83e-4 (favourable) Expressed in all Mixed testis: 18.5 Mixed +ZNF763 ZNF440L ENSG00000197054 Zinc finger protein 763 19 11965037-11980381 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA047845 Uncertain Uncertain Nucleus Mixed Mixed parathyroid gland: 11.5 Cell line enhanced BEWO: 5.9 +ZMYM1 FLJ23151, MYM ENSG00000197056 Zinc finger MYM-type containing 1 1 35059786-35115859 Predicted intracellular proteins Evidence at protein level HPA064019 Approved Microtubule organizing center Liver cancer:3.21e-6 (unfavourable) Expressed in all Mixed testis: 6.9 Mixed +DTHD1 FLJ16686 ENSG00000197057 Death domain containing 1 4 36281622-36345756 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced fallopian tube: 20.9 lung: 4.9 Not detected +HIST1H4C dJ221C16.1, H4/g, H4FG ENSG00000197061 Histone cluster 1 H4 family member c 6 26103876-26104310 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Renal cancer:5.74e-6 (unfavourable) Tissue enhanced Mixed bone marrow: 2.9 Group enriched 5 HEK 293: 31.7;MOLT-4: 6.3;PC-3: 17.3 +ZSCAN26 SRE-ZBP, ZNF187 ENSG00000197062 Zinc finger and SCAN domain containing 26 6 28267010-28278224 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027521 Enhanced Nucleus
Nucleoli Renal cancer:6.79e-5 (unfavourable), Liver cancer:7.81e-5 (unfavourable), Urothelial cancer:1.68e-4 (favourable) Expressed in all Expressed in all ovary: 40.4 Expressed in all +MAFG MGC13090, MGC20149 ENSG00000197063 MAF bZIP transcription factor G 17 81918270-81927714 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB025573 Approved Liver cancer:1.90e-6 (unfavourable), Endometrial cancer:5.82e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.6 Expressed in all +ARRDC1 MGC40555 ENSG00000197070 Arrestin domain containing 1 9 137605654-137615360 Predicted intracellular proteins Evidence at protein level HPA022915, HPA044345 Uncertain Approved Nucleus
Nucleoli Renal cancer:3.59e-4 (favourable) Expressed in all Expressed in all stomach: 26.2 Cell line enhanced MCF7: 150.8 +KIAA1671 ENSG00000197077 KIAA1671 22 24952730-25197448 Predicted intracellular proteins Evidence at protein level HPA018135 Approved Approved Microtubules Renal cancer:3.19e-6 (favourable) Expressed in all Mixed thyroid gland: 44.6 Mixed +KRT35 Ha-5, KRTHA5 ENSG00000197079 Keratin 35 17 41476689-41481140 Plasma proteins, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 8 skin: 2.2 salivary gland,spleen: 0.2 Not detected +IGF2R CD222, CI-M6PR, CI-MPR, CIMPR, M6P-R, MPR1, MPR300, MPRI ENSG00000197081 Insulin like growth factor 2 receptor 6 159969099-160113507 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009661, HPA011332 Supported Enhanced Golgi apparatus
Vesicles Cervical cancer:2.92e-5 (unfavourable), Breast cancer:3.01e-4 (unfavourable), Urothelial cancer:6.08e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.5 Expressed in all +LCE1C LEP3 ENSG00000197084 Late cornified envelope 1C 1 152804835-152806628 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 11 skin: 514.5 breast: 45.5 Cell line enhanced HBEC3-KT: 1.5;hTEC/SVTERT24-B: 1.1;hTERT-HME1: 2.2 +GAL3ST4 FLJ12116 ENSG00000197093 Galactose-3-O-sulfotransferase 4 7 100159244-100168750 Predicted membrane proteins Evidence at protein level HPA038137, HPA038138 Uncertain Approved Nucleoplasm
Cytosol Ovarian cancer:2.57e-4 (unfavourable), Renal cancer:4.14e-4 (unfavourable), Colorectal cancer:5.44e-4 (unfavourable) Expressed in all Tissue enhanced skin: 32.6 smooth muscle: 14.7 Cell line enhanced WM-115: 42.3 +DYNC1H1 CMT2O, DHC1, DNCH1, Dnchc1, DNCL, DNECL, HL-3, p22 ENSG00000197102 Dynein cytoplasmic 1 heavy chain 1 14 101964528-102050792 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003742, CAB010443 Enhanced Supported Centrosome
Cytosol Liver cancer:3.03e-7 (unfavourable), Renal cancer:1.09e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 80.6 Expressed in all +SLC6A17 ENSG00000197106 Solute carrier family 6 member 17 1 110150486-110202202 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA007663, HPA008044 Enhanced Approved Nucleus
Golgi apparatus Tissue enriched Tissue enriched 10 cerebral cortex: 75.4 adrenal gland: 7.9 Cell line enhanced SiHa: 6.6;SK-MEL-30: 28.5;U-87 MG: 7.0 +IFNL3 IL-28B, IL28B, IL28C ENSG00000197110 Interferon lambda 3 19 39243553-39245129 Predicted secreted proteins Evidence at protein level Not detected Not detected testis: 0.2 Not detected +PCBP2 hnRNP-E2, HNRNPE2, HNRPE2 ENSG00000197111 Poly(rC) binding protein 2 12 53452102-53481162 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038356 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:1.82e-5 (unfavourable), Ovarian cancer:8.23e-4 (favourable) Expressed in all Expressed in all thyroid gland: 745.7 Expressed in all +ZGPAT dJ583P15.3, FLJ14972, GPATC6, GPATCH6, KIAA1847, MGC44880, ZC3H9, ZC3HDC9, ZIP ENSG00000197114 Zinc finger CCCH-type and G-patch domain containing 20 63707465-63736142 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056705 Supported Nucleus
Plasma membrane Head and neck cancer:6.17e-5 (favourable) Expressed in all Expressed in all liver: 27.5 Expressed in all +SLC25A29 C14orf69, FLJ38975 ENSG00000197119 Solute carrier family 25 member 29 14 100291111-100306547 Predicted intracellular proteins, Transporters Evidence at protein level HPA030781 Uncertain Pancreatic cancer:2.90e-4 (favourable), Urothelial cancer:5.26e-4 (favourable) Expressed in all Expressed in all thyroid gland: 159.1 Mixed +PGAP1 Bst1, FLJ12377, SPG67 ENSG00000197121 Post-GPI attachment to proteins 1 2 196833004-196927796 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA069704 Uncertain Mixed Mixed skin: 14.6 Mixed +SRC ASV, c-src, SRC1 ENSG00000197122 SRC proto-oncogene, non-receptor tyrosine kinase 20 37344685-37406050 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004023, HPA030875 Approved Enhanced Plasma membrane
Cytosol Liver cancer:4.90e-5 (unfavourable), Urothelial cancer:5.22e-5 (favourable), Renal cancer:1.22e-4 (unfavourable), Prostate cancer:1.63e-4 (unfavourable) Expressed in all Mixed gallbladder: 43.6 Mixed +ZNF679 MGC42415 ENSG00000197123 Zinc finger protein 679 7 64228474-64266931 Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Tissue enriched 17 testis: 1.6 all non-specific tissues: 0.0 Not detected +ZNF682 BC39498_3 ENSG00000197124 Zinc finger protein 682 19 19997058-20039506 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055998 Uncertain Uncertain Golgi apparatus Urothelial cancer:3.51e-4 (favourable) Tissue enhanced Mixed thyroid gland: 13.3 Cell line enhanced AN3-CA: 20.2 +OR8B8 TPCR85 ENSG00000197125 Olfactory receptor family 8 subfamily B member 8 11 124440126-124441158 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF772 DKFZp686I1569 ENSG00000197128 Zinc finger protein 772 19 57466663-57477570 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031312 Uncertain Approved Cytosol Renal cancer:1.02e-6 (favourable) Mixed Mixed parathyroid gland: 20.0 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 28.4 +ZNF257 BMZF-4 ENSG00000197134 Zinc finger protein 257 19 22052452-22091480 Predicted intracellular proteins, Transcription factors Evidence at transcript level Ovarian cancer:2.05e-4 (favourable) Tissue enhanced Mixed testis: 4.2 Cell line enhanced NTERA-2: 11.0;RH-30: 5.6 +PCNX3 FLJ22427, PCNXL3 ENSG00000197136 Pecanex homolog 3 (Drosophila) 11 65615773-65637439 Predicted membrane proteins Evidence at protein level HPA018084 Uncertain Approved Cytosol Expressed in all Mixed testis: 17.2 Expressed in all +ADAM32 ENSG00000197140 ADAM metallopeptidase domain 32 8 39106990-39284911 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA044156, HPA062151 Enhanced Approved Nucleus
Vesicles Not detected Tissue enriched 35 testis: 28.7 skin: 0.8 Cell line enhanced U-2 OS: 1.1 +ACSL5 ACS2, ACS5, FACL5 ENSG00000197142 Acyl-CoA synthetase long-chain family member 5 10 112374018-112428380 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA007162, CAB035986, CAB062546 Enhanced Supported Nucleus
Mitochondria Endometrial cancer:1.13e-4 (favourable) Expressed in all Expressed in all small intestine: 460.3 Cell line enhanced CAPAN-2: 121.7;RT4: 114.0 +LRRC8B KIAA0231, TA-LRRP ENSG00000197147 Leucine rich repeat containing 8 family member B 1 89524836-89597864 Predicted membrane proteins, Transporters Evidence at protein level HPA017950 Uncertain Approved Nuclear speckles Colorectal cancer:7.15e-4 (favourable), Endometrial cancer:9.99e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 37.6 testis: 28.8 Mixed +ABCB8 EST328128, M-ABC1, MABC1 ENSG00000197150 ATP binding cassette subfamily B member 8 7 151028422-151047782 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA045187 Approved Supported Nucleus
Mitochondria Pancreatic cancer:3.34e-4 (favourable), Renal cancer:5.88e-4 (favourable), Head and neck cancer:5.91e-4 (favourable) Expressed in all Expressed in all thyroid gland: 17.1 Expressed in all +HIST1H3J H3/j, H3FJ ENSG00000197153 Histone cluster 1 H3 family member j 6 27890382-27893106 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Mixed Tissue enhanced lymph node: 1.5 testis: 0.9 Cell line enhanced U-266/84: 8.5 +SND1 p100, TDRD11 ENSG00000197157 Staphylococcal nuclease and tudor domain containing 1 7 127652180-128092609 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002529, HPA002632, CAB019323 Enhanced Enhanced Cytosol Endometrial cancer:1.95e-4 (favourable) Expressed in all Expressed in all placenta: 122.3 Expressed in all +ZNF785 FLJ32130 ENSG00000197162 Zinc finger protein 785 16 30573740-30585771 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030510 Approved Nucleoplasm
Plasma membrane Pancreatic cancer:2.03e-5 (favourable), Lung cancer:8.99e-4 (favourable) Expressed in all Expressed in all endometrium: 11.7 Mixed +SULT1A2 HAST4, STP2 ENSG00000197165 Sulfotransferase family 1A member 2 16 28591943-28597109 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049500, HPA051051 Supported Tissue enhanced Tissue enhanced duodenum: 49.2;small intestine: 49.2 liver: 21.0 Cell line enhanced BEWO: 9.6;EFO-21: 12.0;Hep G2: 33.5 +NEK5 ENSG00000197168 NIMA related kinase 5 13 52033611-52129078 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035565, HPA041399 Enhanced Mixed Group enriched 8 fallopian tube: 12.2;testis: 18.7 lung: 1.9 Cell line enhanced T-47d: 1.0 +PSMD12 p55, Rpn5 ENSG00000197170 Proteasome 26S subunit, non-ATPase 12 17 67337916-67366627 Predicted intracellular proteins Evidence at protein level HPA023119 Enhanced Approved Nucleus
Microtubules
Cytosol Renal cancer:4.73e-6 (unfavourable), Liver cancer:1.21e-4 (unfavourable), Colorectal cancer:4.39e-4 (favourable), Ovarian cancer:6.32e-4 (favourable) Expressed in all Expressed in all testis: 26.2 Expressed in all +MAGEA6 CT1.6, MAGE6 ENSG00000197172 MAGE family member A6 X 152766136-152769747 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Liver cancer:1.93e-4 (unfavourable) Mixed Tissue enriched 22 testis: 10.9 endometrium: 0.4 Cell line enhanced HMC-1: 137.9;K-562: 121.3;PC-3: 136.2;SK-BR-3: 103.8;U-2 OS: 104.5;U-266/70: 133.8 +ADGRA1 GPR123, KIAA1828 ENSG00000197177 Adhesion G protein-coupled receptor A1 10 133070929-133131675 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA042773 Approved Tissue enriched Tissue enhanced adrenal gland: 4.9;cerebral cortex: 22.4 fallopian tube: 3.1 Cell line enriched 24 RH-30: 6.1 +PIWIL2 CT80, FLJ10351, HILI, Mili ENSG00000197181 Piwi like RNA-mediated gene silencing 2 8 22275297-22357563 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 9 testis: 53.4 duodenum: 6.1 Cell line enriched 21 NTERA-2: 38.0 +NOL4L C20orf112, C20orf113, dJ1184F4.2, dJ1184F4.4, DKFZP566G1424 ENSG00000197183 Nucleolar protein 4 like 20 32443059-32585074 Predicted intracellular proteins Evidence at protein level HPA041768, HPA043600 Enhanced Enhanced Nucleoplasm Endometrial cancer:1.01e-4 (unfavourable), Urothelial cancer:2.63e-4 (favourable) Expressed in all Tissue enhanced testis: 60.2 small intestine: 21.8 Cell line enhanced CACO-2: 60.7 +CYSRT1 C9orf169, MGC59937 ENSG00000197191 Cysteine rich tail 1 9 137224635-137226311 Predicted intracellular proteins Evidence at protein level HPA021883, HPA021886 Approved Approved Nuclear speckles
Vesicles
Midbody Expressed in all Tissue enhanced esophagus: 45.6;skin: 12.2 tonsil: 6.3 Cell line enhanced A-431: 11.7;CAPAN-2: 14.5;HaCaT: 16.3;MCF7: 20.0 +SLC22A4 DFNB60, MGC34546, OCTN1 ENSG00000197208 Solute carrier family 22 member 4 5 132294443-132344206 Disease related genes, Predicted membrane proteins Evidence at protein level CAB015468, HPA036974 Approved Approved Mitochondria Mixed Tissue enhanced fallopian tube: 18.4 bone marrow: 13.2 Cell line enhanced BJ hTERT+: 48.5;U-138 MG: 24.5 +ZSCAN5B ZNF371, ZNF495B ENSG00000197213 Zinc finger and SCAN domain containing 5B 19 56189570-56197920 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043123, HPA046836, HPA059494, HPA060667 Uncertain Uncertain Nuclear speckles Not detected Tissue enriched 22 testis: 2.7 fallopian tube: 0.1 Not detected +ENTPD4 KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase ENSG00000197217 Ectonucleoside triphosphate diphosphohydrolase 4 8 23385783-23457695 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017655 Supported Supported Vesicles Expressed in all Expressed in all parathyroid gland: 47.3 Expressed in all +C1D LRP1, Rrp47, SUN-CoR, SUNCOR ENSG00000197223 C1D nuclear receptor corepressor 2 68041130-68110948 Predicted intracellular proteins Evidence at protein level HPA037413, HPA037588 Approved Enhanced Nucleus
Nucleoli Expressed in all Expressed in all thyroid gland: 51.9 Expressed in all +TBC1D9B GRAMD9B, KIAA0676 ENSG00000197226 TBC1 domain family member 9B 5 179862066-179907859 Predicted intracellular proteins Evidence at protein level HPA038350 Approved Approved Nucleus
Nucleoli fibrillar center
Plasma membrane Thyroid cancer:3.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 30.3 Expressed in all +OR1J2 OR1J3, OR1J5, OST044 ENSG00000197233 Olfactory receptor family 1 subfamily J member 2 9 122510802-122511743 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected urinary bladder: 0.2 Not detected +HIST1H4J H4/e, H4F2iv, H4FE ENSG00000197238 Histone cluster 1 H4 family member j 6 27824108-27824480 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Mixed Mixed bone marrow: 15.2 Mixed +SLC2A7 GLUT7 ENSG00000197241 Solute carrier family 2 member 7 1 9003300-9026345 Predicted membrane proteins, Transporters Evidence at protein level HPA039931 Uncertain Not detected Group enriched 8 duodenum: 3.0;small intestine: 3.1 epididymis,testis: 0.3 Not detected +FAM110D FLJ14050, GRRP1 ENSG00000197245 Family with sequence similarity 110 member D 1 26159020-26163962 Predicted intracellular proteins Evidence at transcript level HPA013664 Approved Expressed in all Mixed adipose tissue: 4.9 Cell line enhanced U-2 OS: 1.6 +SERPINA1 A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1 ENSG00000197249 Serpin family A member 1 14 94376747-94390693 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000927, HPA001292, CAB013211, CAB016648, CAB073396 Enhanced Enhanced Vesicles Breast cancer:1.61e-5 (favourable), Colorectal cancer:5.86e-4 (favourable) Tissue enriched Tissue enriched 20 liver: 17144.0 small intestine: 857.0 Cell line enriched 6 Hep G2: 3254.2 +TPSB2 ENSG00000197253 Tryptase beta 2 (gene/pseudogene) 16 1227272-1230184 Enzymes, Predicted secreted proteins Evidence at protein level HPA049153, HPA049554 Supported Mixed Tissue enhanced gallbladder: 156.9 lung: 117.5 Cell line enriched 7 HMC-1: 262.0 +KANK2 ANKRD25, KIAA1518, MXRA3 ENSG00000197256 KN motif and ankyrin repeat domains 2 19 11164267-11197791 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA015643 Approved Renal cancer:8.73e-5 (unfavourable) Expressed in all Expressed in all endometrium: 439.0 Expressed in all +C6orf141 MGC46457 ENSG00000197261 Chromosome 6 open reading frame 141 6 49550646-49561907 Predicted intracellular proteins Evidence at protein level HPA036199 Uncertain Approved Nuclear membrane Breast cancer:3.92e-6 (favourable), Endometrial cancer:1.15e-4 (favourable) Mixed Tissue enhanced gallbladder: 9.3 duodenum: 6.2 Cell line enhanced HaCaT: 7.6;PC-3: 10.6;T-47d: 6.8 +GTF2E2 FE, TF2E2, TFIIE-B ENSG00000197265 General transcription factor IIE subunit 2 8 30578318-30658251 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA004816, CAB009603, HPA025065 Approved Enhanced Nucleoplasm
Cytosol Renal cancer:5.82e-7 (unfavourable) Expressed in all Expressed in all testis: 52.7 Expressed in all +IL27 IL-27, IL-27A, IL27A, IL27p28, IL30, MGC71873, p28 ENSG00000197272 Interleukin 27 16 28499362-28512051 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB024722 Approved Liver cancer:1.30e-4 (favourable) Tissue enriched Tissue enhanced liver: 8.0 appendix: 1.6 Cell line enriched 15 BEWO: 17.2 +GUCA2A GUCA2, STARA ENSG00000197273 Guanylate cyclase activator 2A 1 42162691-42164718 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA018215 Enhanced Group enriched Group enriched 15 colon: 768.8;rectum: 859.2;small intestine: 1127.0 duodenum: 61.5 Cell line enhanced BEWO: 11.8;CACO-2: 8.2;NB-4: 2.0;U-2197: 2.5 +RAD54B RDH54 ENSG00000197275 RAD54 homolog B (S. cerevisiae) 8 94371960-94475109 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007087 Uncertain Mixed Mixed testis: 7.8 Mixed +ZNF165 CT53, ZSCAN7 ENSG00000197279 Zinc finger protein 165 6 28080975-28089563 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007247 Approved Nuclear speckles
Microtubules Renal cancer:1.19e-5 (favourable), Urothelial cancer:9.82e-5 (favourable), Ovarian cancer:2.10e-4 (favourable) Mixed Tissue enhanced testis: 35.8 epididymis: 7.5 Cell line enhanced BEWO: 23.4 +SYNGAP1 KIAA1938, RASA5, SYNGAP ENSG00000197283 Synaptic Ras GTPase activating protein 1 6 33419661-33457541 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA038373 Enhanced Approved Nucleus Renal cancer:1.34e-6 (unfavourable), Head and neck cancer:2.80e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 26.3 endometrium: 12.5 Cell line enhanced AF22: 28.5 +FITM2 C20orf142, dJ881L22.2, FIT2 ENSG00000197296 Fat storage inducing transmembrane protein 2 20 44302838-44311169 Predicted membrane proteins Evidence at protein level Renal cancer:8.98e-12 (favourable) Expressed in all Tissue enhanced heart muscle: 40.1 parathyroid gland: 24.1 Mixed +BLM BS, RECQ2, RECQL3 ENSG00000197299 Bloom syndrome RecQ like helicase 15 90717327-90816165 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005689 Approved Supported Nucleus
Cytosol Mixed Mixed lymph node: 3.8 Mixed +ZNF720 ENSG00000197302 Zinc finger protein 720 16 31713229-31794869 Predicted intracellular proteins Evidence at transcript level HPA041570 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 15.5 Expressed in all +OR10D3 HTPCRX09, OR10D3P ENSG00000197309 Olfactory receptor family 10 subfamily D member 3 (putative) 11 124185216-124186245 G-protein coupled receptors, Predicted membrane proteins No evidence HPA049991 Uncertain Not detected Not detected testis: 0.3 Not detected +DDI2 MGC14844 ENSG00000197312 DNA damage inducible 1 homolog 2 1 15617500-15669044 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043119, HPA043225 Approved Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 19.7 Expressed in all +SVIL ENSG00000197321 Supervillin 10 29457338-29736781 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010878, HPA020095, HPA020138 Approved Supported Plasma membrane
Actin filaments
Cytosol Urothelial cancer:5.70e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 279.8 Cell line enhanced HaCaT: 106.2 +TRIM33 FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA ENSG00000197323 Tripartite motif containing 33 1 114392777-114511160 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004345 Supported Approved Nucleoplasm
Vesicles Colorectal cancer:6.20e-4 (favourable), Head and neck cancer:8.93e-4 (favourable) Expressed in all Expressed in all testis: 46.2 Expressed in all +LRP10 DKFZP564C1940, LRP9, MGC8675, MST087, MSTP087 ENSG00000197324 LDL receptor related protein 10 14 22871613-22881580 Predicted membrane proteins Evidence at protein level HPA000932 Approved Nucleus
Nucleoli Liver cancer:3.54e-7 (unfavourable), Renal cancer:6.31e-5 (favourable), Lung cancer:9.17e-4 (unfavourable) Expressed in all Expressed in all esophagus: 179.5 Expressed in all +PELI1 ENSG00000197329 Pellino E3 ubiquitin protein ligase 1 2 64092652-64144454 Enzymes, Predicted intracellular proteins Evidence at protein level HPA053182 Uncertain Approved Nucleus
Nucleoli
Intermediate filaments Renal cancer:5.67e-6 (unfavourable), Endometrial cancer:5.33e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 143.9 Cell line enhanced U-698: 99.2 +ZNF655 VIK, VIK-1 ENSG00000197343 Zinc finger protein 655 7 99558406-99576453 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029534, HPA050750 Uncertain Supported Nucleoplasm
Plasma membrane Breast cancer:7.12e-4 (favourable), Melanoma:7.24e-4 (unfavourable) Expressed in all Expressed in all lymph node: 21.2 Mixed +MRPL21 ENSG00000197345 Mitochondrial ribosomal protein L21 11 68891276-68903835 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA051657 Approved Approved Nucleoplasm
Mitochondria Head and neck cancer:5.97e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 75.1 Expressed in all +LYPD2 LYPDC2, RGTR430, UNQ430 ENSG00000197353 LY6/PLAUR domain containing 2 8 142750150-142752534 Predicted secreted proteins Evidence at protein level HPA028599 Uncertain Cervical cancer:2.00e-4 (favourable), Head and neck cancer:2.63e-4 (favourable) Group enriched Tissue enhanced esophagus: 99.1;tonsil: 24.0 stomach: 20.9 Group enriched 20 EFO-21: 9.5;HaCaT: 2.5 +UAP1L1 ENSG00000197355 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 9 137077501-137084539 Predicted intracellular proteins Evidence at protein level HPA044356 Approved Approved Intermediate filaments
Cytosol Liver cancer:3.77e-4 (unfavourable), Pancreatic cancer:5.23e-4 (favourable) Expressed in all Mixed spleen: 13.2 Mixed +ZNF98 F7175, ZNF739 ENSG00000197360 Zinc finger protein 98 19 22391019-22532485 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at transcript level Tissue enhanced Tissue enhanced ovary: 14.4;testis: 14.1 thyroid gland: 7.9 Cell line enhanced BEWO: 1.7;NB-4: 3.0;T-47d: 3.2;U-2197: 3.3 +FBXL22 Fbl22, FLJ39626 ENSG00000197361 F-box and leucine rich repeat protein 22 15 63597353-63602428 Predicted intracellular proteins Evidence at protein level HPA047624, HPA054627 Uncertain Uncertain Nucleoli
Cytosol Mixed Tissue enhanced endometrium: 50.4;seminal vesicle: 44.0;smooth muscle: 46.1 prostate: 23.3 Cell line enhanced MCF7: 3.7;SCLC-21H: 6.3 +ZNF786 DKFZp762I137 ENSG00000197362 Zinc finger protein 786 7 149069643-149090782 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021518, HPA053459 Uncertain Approved Nucleoplasm
Nuclear speckles Liver cancer:1.09e-4 (unfavourable), Pancreatic cancer:2.01e-4 (favourable) Expressed in all Mixed skin: 7.2 Expressed in all +ZNF517 ENSG00000197363 Zinc finger protein 517 8 144798876-144811169 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055337 Approved Nucleoplasm Pancreatic cancer:1.66e-4 (favourable) Expressed in all Mixed skin: 7.5 Mixed +S100A7L2 s100a7b ENSG00000197364 S100 calcium binding protein A7 like 2 1 153437058-153439949 Predicted intracellular proteins Evidence at protein level HPA057828 Uncertain Not detected Not detected testis: 0.1 Not detected +ZNF675 TBZF, TIZ ENSG00000197372 Zinc finger protein 675 19 23525631-23687220 Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Expressed in all testis: 25.1 Cell line enhanced HDLM-2: 56.3 +SLC22A5 CDSP, OCTN2, SCD ENSG00000197375 Solute carrier family 22 member 5 5 132369752-132395614 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA063062 Approved Mitochondria Endometrial cancer:2.87e-5 (favourable), Pancreatic cancer:7.36e-4 (favourable), Renal cancer:8.36e-4 (favourable) Expressed in all Mixed parathyroid gland: 32.1 Cell line enhanced SiHa: 40.6 +OR8S1 ENSG00000197376 Olfactory receptor family 8 subfamily S member 1 12 48507354-48529897 G-protein coupled receptors, Predicted membrane proteins No evidence HPA045595 Uncertain Approved Plasma membrane Not detected Not detected testis: 0.1 Not detected +DACT3 DAPPER3, MGC15476, RRR1 ENSG00000197380 Dishevelled binding antagonist of beta catenin 3 19 46647612-46661138 Predicted intracellular proteins Evidence at protein level HPA043053 Approved Approved Nucleoplasm
Vesicles Renal cancer:7.97e-8 (unfavourable), Urothelial cancer:6.66e-4 (unfavourable) Mixed Mixed smooth muscle: 46.6 Cell line enhanced SH-SY5Y: 26.8 +ADARB1 ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1 ENSG00000197381 Adenosine deaminase, RNA specific B1 21 45073853-45226560 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029645 Supported Nucleoplasm
Cytosol Colorectal cancer:8.16e-5 (unfavourable), Renal cancer:3.56e-4 (unfavourable) Expressed in all Expressed in all lung: 30.2 Cell line enhanced HHSteC: 55.4 +ZNF860 ENSG00000197385 Zinc finger protein 860 3 31981771-31991628 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA063386 Uncertain Approved Nucleus
Nucleoli Mixed Mixed prostate: 4.7 Cell line enriched 6 BEWO: 44.1 +HTT HD, IT15 ENSG00000197386 Huntingtin 4 3074681-3243959 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002756, HPA026114 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:2.41e-12 (favourable), Head and neck cancer:3.26e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.3 Expressed in all +OR6N1 ENSG00000197403 Olfactory receptor family 6 subfamily N member 1 1 158765744-158766682 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected bone marrow: 0.6 Not detected +C5AR1 C5A, C5AR, C5R1, CD88 ENSG00000197405 Complement C5a receptor 1 19 47290023-47322066 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002720, HPA014520 Approved Renal cancer:1.16e-4 (unfavourable), Cervical cancer:4.71e-4 (favourable), Testis cancer:7.99e-4 (unfavourable), Ovarian cancer:9.55e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 121.2 adipose tissue: 91.2 Cell line enhanced HMC-1: 4.6;U-87 MG: 6.2;U-937: 5.1 +DIO3 TXDI3 ENSG00000197406 Iodothyronine deiodinase 3 14 101561351-101563452 Enzymes, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced cervix, uterine: 27.8;placenta: 25.4 ovary: 6.2 Cell line enriched 37 AF22: 53.5 +CYP2B6 CPB6, CYP2B, CYPIIB6 ENSG00000197408 Cytochrome P450 family 2 subfamily B member 6 19 40991299-41018398 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB033866, HPA048124, HPA062973 Supported Approved Nucleoplasm
Nuclear membrane
Cytosol Tissue enhanced Tissue enriched 18 liver: 283.3 kidney: 15.7 Cell line enhanced HaCaT: 2.3 +HIST1H3D H3/b, H3FB ENSG00000197409 Histone cluster 1 H3 family member d 6 26196840-26197250 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Renal cancer:1.78e-6 (unfavourable) Expressed in all Tissue enriched 8 bone marrow: 6.5 adrenal gland: 0.8 Cell line enhanced Karpas-707: 4.0;U-266/70: 6.0 +DCHS2 CDH27, CDHJ, CDHR7, FLJ20047, PCDH23, PCDHJ ENSG00000197410 Dachsous cadherin-related 2 4 154232037-154491716 Predicted membrane proteins Evidence at protein level HPA064159 Uncertain Approved Vesicles
Plasma membrane Not detected Tissue enhanced endometrium: 1.9 testis: 1.7 Cell line enriched 6 U-2 OS: 9.2 +VEPH1 FLJ12604, KIAA1692 ENSG00000197415 Ventricular zone expressed PH domain containing 1 3 157259742-157533619 Predicted intracellular proteins Evidence at protein level HPA026645 Uncertain Approved Nucleus
Nucleoli
Cytosol Renal cancer:7.75e-9 (favourable) Mixed Tissue enhanced adrenal gland: 26.6;kidney: 28.8;lung: 43.9 epididymis: 21.4 Cell line enhanced HUVEC TERT2: 204.2;TIME: 119.8 +FABP12 ENSG00000197416 Fatty acid binding protein 12 8 81524981-81531378 Predicted intracellular proteins Evidence at protein level HPA044041 Approved Tissue enhanced Group enriched 13 esophagus: 4.3;testis: 15.4 lung: 0.7 Not detected +SHPK CARKL, SHK ENSG00000197417 Sedoheptulokinase 17 3608262-3636322 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA024361, HPA064939 Enhanced Approved Nucleoplasm
Nuclear speckles Expressed in all Mixed duodenum: 13.4 Expressed in all +OR51D1 OR51D1Q ENSG00000197428 Olfactory receptor family 51 subfamily D member 1 11 4639715-4640838 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA061240 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +IPP KLHL27 ENSG00000197429 Intracisternal A particle-promoted polypeptide 1 45694324-45750650 Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:1.11e-4 (favourable), Liver cancer:2.27e-4 (unfavourable), Colorectal cancer:9.11e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 19.8 Mixed +OPALIN HTMP10, TMEM10, TMP10 ENSG00000197430 Oligodendrocytic myelin paranodal and inner loop protein 10 96343216-96359365 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014372 Supported Tissue enriched Tissue enriched 864 cerebral cortex: 86.3 all non-specific tissues: 0.0 Not detected +OR13G1 ENSG00000197437 Olfactory receptor family 13 subfamily G member 1 1 247672118-247673041 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.3 Not detected +MAP3K5 ASK1, MAPKKK5, MEKK5 ENSG00000197442 Mitogen-activated protein kinase kinase kinase 5 6 136557047-136792518 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007824, HPA063245, HPA064423 Approved Supported Cytosol Pancreatic cancer:5.91e-4 (unfavourable), Head and neck cancer:6.08e-4 (favourable) Expressed in all Expressed in all adrenal gland: 115.7 Mixed +OGDHL FLJ10851 ENSG00000197444 Oxoglutarate dehydrogenase-like 10 49734643-49762379 Citric acid cycle related proteins, Predicted intracellular proteins Evidence at protein level HPA052497 Enhanced Approved Nucleus
Nucleoli fibrillar center
Cytosol Renal cancer:1.21e-14 (favourable) Tissue enhanced Tissue enhanced kidney: 128.4;parathyroid gland: 56.3 liver: 41.6 Cell line enhanced AN3-CA: 19.8;RPTEC TERT1: 32.9;SH-SY5Y: 17.3 +CYP2F1 CYP2F ENSG00000197446 Cytochrome P450 family 2 subfamily F member 1 19 41114432-41128366 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Group enriched 8 lung: 2.4;testis: 1.9 bone marrow,esophagus,tonsil: 0.2 Group enriched 16 HMC-1: 4.7;K-562: 4.5 +GSTK1 GST13 ENSG00000197448 Glutathione S-transferase kappa 1 7 143244093-143270854 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006311, HPA022904 Enhanced Supported Peroxisomes Renal cancer:2.10e-6 (favourable), Breast cancer:4.41e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 377.4 Expressed in all +HNRNPAB ABBP1, FLJ40338, HNRPAB ENSG00000197451 Heterogeneous nuclear ribonucleoprotein A/B 5 178204507-178211163 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046688 Approved Enhanced Nucleoplasm Renal cancer:1.35e-7 (unfavourable), Ovarian cancer:9.79e-4 (favourable) Expressed in all Expressed in all colon: 141.3 Expressed in all +OR2L5 OR2L11, OR2L5P ENSG00000197454 Olfactory receptor family 2 subfamily L member 5 1 248021948-248022886 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +STMN3 SCLIP ENSG00000197457 Stathmin 3 20 63639705-63657682 Predicted intracellular proteins Evidence at protein level HPA012947 Enhanced Expressed in all Tissue enhanced cerebral cortex: 225.7 thyroid gland: 52.6 Cell line enhanced SCLC-21H: 225.8;SH-SY5Y: 155.0 +PDGFA PDGF-A, PDGF1 ENSG00000197461 Platelet derived growth factor subunit A 7 497258-520296 Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB005579 Uncertain Approved Vesicles
Microtubule organizing center Glioma:1.51e-4 (unfavourable), Head and neck cancer:1.78e-4 (unfavourable), Urothelial cancer:8.67e-4 (unfavourable) Expressed in all Expressed in all placenta: 38.8 Cell line enhanced WM-115: 307.1 +GYPE GPE, MNS ENSG00000197465 Glycophorin E (MNS blood group) 4 143870867-143905563 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced bone marrow: 8.1 lung: 4.5 Group enriched 14 HEL: 108.6;K-562: 35.5 +COL13A1 ENSG00000197467 Collagen type XIII alpha 1 chain 10 69801931-69964275 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050392 Approved Mixed Tissue enhanced epididymis: 32.9 prostate: 20.4 Cell line enhanced HUVEC TERT2: 78.6;PC-3: 69.5;TIME: 103.7 +SPN CD43, GPL115, LSN ENSG00000197471 Sialophorin 16 29662979-29670876 CD markers, Predicted membrane proteins Evidence at protein level CAB002666, HPA055244 Enhanced Uncertain Golgi apparatus
Plasma membrane
Cell Junctions Endometrial cancer:3.08e-5 (favourable), Breast cancer:1.40e-4 (favourable), Melanoma:1.88e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 38.6;lung: 33.3 lymph node: 25.4 Cell line enhanced HEL: 209.9;HL-60: 167.0;HMC-1: 98.8;U-937: 115.3 +ZNF695 SBZF3 ENSG00000197472 Zinc finger protein 695 1 246945547-247008093 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024743 Uncertain Approved Nuclear speckles Mixed Tissue enhanced testis: 1.2 small intestine: 0.6 Mixed +PCDHB11 ME2, PCDH-BETA11 ENSG00000197479 Protocadherin beta 11 5 141199582-141203779 Predicted membrane proteins Evidence at transcript level HPA045042 Uncertain Approved Plasma membrane Mixed Tissue enhanced parathyroid gland: 8.2 endometrium: 2.5 Cell line enhanced AN3-CA: 5.1;EFO-21: 7.4 +ZNF628 ZEC, Zfp628 ENSG00000197483 Zinc finger protein 628 19 55476332-55484487 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044451 Uncertain Approved Nucleoplasm Expressed in all Tissue enhanced testis: 7.2 spleen: 2.7 Mixed +GALP ENSG00000197487 Galanin like peptide 19 56176020-56185775 Predicted secreted proteins Evidence at transcript level HPA053938 Uncertain Tissue enhanced Not detected liver: 0.3 Not detected +SLC2A10 GLUT10 ENSG00000197496 Solute carrier family 2 member 10 20 46709487-46736347 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041015 Approved Approved Nucleoplasm
Vesicles Expressed in all Mixed prostate: 49.3 Cell line enhanced SK-MEL-30: 45.7 +ZNF665 FLJ14345 ENSG00000197497 Zinc finger protein 665 19 53159213-53193386 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA023437 Uncertain Approved Nuclear membrane Mixed Mixed ovary: 3.7 Mixed +RPF2 bA397G5.4, BXDC1, FLJ21087 ENSG00000197498 Ribosome production factor 2 homolog 6 110982015-111028263 Predicted intracellular proteins Evidence at protein level HPA035475 Supported Supported Nucleus
Nucleoli Renal cancer:2.07e-6 (unfavourable), Head and neck cancer:2.04e-4 (unfavourable), Liver cancer:2.25e-4 (unfavourable) Expressed in all Expressed in all testis: 28.2 Expressed in all +SLC28A3 CNT3 ENSG00000197506 Solute carrier family 28 member 3 9 84275457-84340683 Predicted membrane proteins, Transporters Evidence at protein level HPA023311, HPA024729 Approved Breast cancer:3.37e-4 (favourable) Mixed Tissue enhanced breast: 10.7;gallbladder: 11.7;skin: 9.8 bone marrow: 6.2 Cell line enriched 8 HMC-1: 51.9 +FAM177B FLJ43505, RP11-452F19.2 ENSG00000197520 Family with sequence similarity 177 member B 1 222737207-222750805 Predicted intracellular proteins Evidence at transcript level HPA063059 Uncertain Mixed Tissue enhanced stomach: 47.3 gallbladder: 15.8 Not detected +MIB2 FLJ39787, skeletrophin, ZZANK1, ZZZ5 ENSG00000197530 Mindbomb E3 ubiquitin protein ligase 2 1 1615415-1630610 Enzymes, Predicted intracellular proteins Evidence at protein level HPA068322 Enhanced Expressed in all Tissue enhanced skeletal muscle: 12.4 cerebral cortex: 4.4 Cell line enhanced SCLC-21H: 18.4 +OR6Y1 OR6Y2 ENSG00000197532 Olfactory receptor family 6 subfamily Y member 1 1 158547128-158548105 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +MYO5A GS1, MYH12, MYO5, MYR12 ENSG00000197535 Myosin VA 15 52307283-52529050 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001356 Approved Approved Focal adhesion sites
Microtubule organizing center Urothelial cancer:4.22e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 96.4 Cell line enhanced Karpas-707: 145.4 +C5orf56 ENSG00000197536 Chromosome 5 open reading frame 56 5 132410636-132488702 Predicted intracellular proteins Evidence at transcript level HPA043790 Approved Mitochondria Renal cancer:3.13e-6 (unfavourable) Mixed Mixed spleen: 25.0 Cell line enhanced Karpas-707: 38.7;U-266/70: 24.5 +GZMM LMET1, MET1 ENSG00000197540 Granzyme M 19 544034-549924 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA015624 Enhanced Head and neck cancer:1.87e-7 (favourable), Renal cancer:1.21e-4 (unfavourable), Endometrial cancer:1.89e-4 (favourable) Expressed in all Tissue enhanced lymph node: 20.9;spleen: 19.7 appendix: 13.0 Cell line enhanced EFO-21: 1.9;HDLM-2: 1.6;HMC-1: 1.8;MOLT-4: 1.1 +ATG7 APG7L, DKFZp434N0735, GSA7 ENSG00000197548 Autophagy related 7 3 11272309-11557665 Predicted intracellular proteins Evidence at protein level HPA007639, CAB018771 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.41e-4 (unfavourable), Renal cancer:9.55e-4 (favourable), Colorectal cancer:9.66e-4 (favourable) Expressed in all Expressed in all testis: 40.7 Expressed in all +SIPA1L1 E6TP1, KIAA0440 ENSG00000197555 Signal induced proliferation associated 1 like 1 14 71320449-71741229 Predicted intracellular proteins Evidence at protein level HPA002875 Approved Approved Plasma membrane
Actin filaments Renal cancer:6.80e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 47.0 Mixed +TTC30A FLJ13946, IFT70A ENSG00000197557 Tetratricopeptide repeat domain 30A 2 177612992-177618966 Predicted intracellular proteins Evidence at protein level HPA051714, HPA052100, HPA052487 Supported Approved Nucleus
Centrosome Glioma:9.98e-4 (unfavourable) Expressed in all Mixed testis: 17.3 Mixed +SSPO FLJ36112, KIAA0543, SCO-spondin ENSG00000197558 SCO-spondin 7 149776042-149833979 Predicted secreted proteins Evidence at protein level Not detected Not detected cerebral cortex: 0.4 Not detected +ELANE ELA2, HLE, HNE, NE ENSG00000197561 Elastase, neutrophil expressed 19 851014-856247 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB015409, HPA066836 Enhanced Group enriched Tissue enriched 320 bone marrow: 1199.6 skin: 3.7 Cell line enriched 56 THP-1: 1171.3 +RAB40C RARL, RASL8C ENSG00000197562 RAB40C, member RAS oncogene family 16 589357-629272 Predicted intracellular proteins Evidence at protein level Liver cancer:1.18e-4 (unfavourable) Expressed in all Expressed in all skin: 26.5 Expressed in all +PIGN MDC4, PIG-N ENSG00000197563 Phosphatidylinositol glycan anchor biosynthesis class N 18 61905255-62187118 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039922, HPA040374 Approved Supported Plasma membrane
Cytosol Colorectal cancer:6.51e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 33.4 Expressed in all +COL4A6 ENSG00000197565 Collagen type IV alpha 6 chain X 108155607-108439497 Disease related genes, Predicted secreted proteins Evidence at protein level HPA065393 Approved Endoplasmic reticulum Mixed Mixed smooth muscle: 36.9 Cell line enhanced HBEC3-KT: 32.9;HHSteC: 49.7;hTERT-HME1: 33.8;HUVEC TERT2: 34.7;TIME: 76.5 +ZNF624 KIAA1349 ENSG00000197566 Zinc finger protein 624 17 16620737-16653856 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023157, HPA023244 Uncertain Approved Vesicles Mixed Mixed testis: 9.0 Mixed +HHLA3 ENSG00000197568 HERV-H LTR-associating 3 1 70354805-70385339 Predicted intracellular proteins Evidence at protein level HPA031323 Approved Approved Nucleoplasm
Vesicles Renal cancer:2.03e-4 (unfavourable) Expressed in all Mixed epididymis: 21.7 Expressed in all +HOXA4 HOX1, HOX1D ENSG00000197576 Homeobox A4 7 27128507-27130799 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060088 Approved Enhanced Nuclear bodies Endometrial cancer:6.37e-4 (unfavourable) Mixed Tissue enhanced fallopian tube: 37.3;parathyroid gland: 35.3 esophagus: 16.4 Cell line enhanced AN3-CA: 26.9;WM-115: 28.7 +TOPORS LUN, RP31, TP53BPL ENSG00000197579 TOP1 binding arginine/serine rich protein 9 32540544-32552553 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA060640, HPA065661 Enhanced Supported Nucleoplasm Renal cancer:6.64e-6 (favourable), Ovarian cancer:7.07e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.6 Expressed in all +BCO2 B-DIOX-II, BCDO2, FLJ34464 ENSG00000197580 Beta-carotene oxygenase 2 11 112175467-112224699 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039825, HPA040695 Uncertain Mixed Tissue enhanced heart muscle: 21.7;liver: 25.7 adrenal gland: 16.9 Cell line enhanced CAPAN-2: 5.2;HHSteC: 10.3 +KCNMB2 ENSG00000197584 Potassium calcium-activated channel subfamily M regulatory beta subunit 2 3 178272932-178844429 Predicted membrane proteins, Transporters Evidence at protein level CAB022649 Uncertain Mixed Tissue enhanced epididymis: 43.1;fallopian tube: 22.3;ovary: 19.0 adrenal gland: 7.6 Cell line enhanced BJ hTERT+: 2.5;SCLC-21H: 4.7 +ENTPD6 CD39L2, dJ738P15.3, IL6ST2, NTPDase-6 ENSG00000197586 Ectonucleoside triphosphate diphosphohydrolase 6 (putative) 20 25195693-25226729 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015491, HPA069555 Approved Supported Golgi apparatus Expressed in all Expressed in all cerebral cortex: 105.7 Expressed in all +DMBX1 OTX3, PAXB ENSG00000197587 Diencephalon/mesencephalon homeobox 1 1 46506996-46514226 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026811 Uncertain Endometrial cancer:7.13e-5 (unfavourable) Mixed Tissue enhanced testis: 1.2 adrenal gland,thyroid gland: 0.4 Cell line enhanced AN3-CA: 11.9;CAPAN-2: 3.6;K-562: 3.9;SiHa: 4.4 +OR11L1 ENSG00000197591 Olfactory receptor family 11 subfamily L member 1 1 247840928-247841896 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected thyroid gland: 0.3 Not detected +ENPP1 M6S1, NPPS, PC-1, PCA1, PDNP1 ENSG00000197594 Ectonucleotide pyrophosphatase/phosphodiesterase 1 6 131808016-131895155 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB032904, HPA062066 Enhanced Expressed in all Tissue enhanced parathyroid gland: 54.3;placenta: 62.9 thyroid gland: 34.1 Cell line enhanced ASC diff: 23.4;U-138 MG: 27.3 +CCDC154 C16orf29, LOC645811 ENSG00000197599 Coiled-coil domain containing 154 16 1434383-1444556 Predicted intracellular proteins Evidence at protein level HPA041158, HPA043535, HPA048237 Uncertain Approved Golgi apparatus
Plasma membrane Mixed Tissue enhanced testis: 6.5 spleen: 2.5 Group enriched 5 A-431: 8.2;SCLC-21H: 37.5 +FAR1 FLJ22728, MLSTD2, SDR10E1 ENSG00000197601 Fatty acyl-CoA reductase 1 11 13668670-13732346 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017322 Approved Enhanced Peroxisomes Colorectal cancer:2.27e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 58.9 Mixed +C5orf42 FLJ13231, Hug, JBTS17 ENSG00000197603 Chromosome 5 open reading frame 42 5 37106228-37249428 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036775, HPA036776 Approved Approved Cytosol Mixed Mixed thyroid gland: 13.8 Cell line enhanced SiHa: 60.3 +ZNF841 LOC284371 ENSG00000197608 Zinc finger protein 841 19 52064466-52095765 Predicted intracellular proteins, Transcription factors Evidence at transcript level Renal cancer:3.56e-6 (unfavourable), Urothelial cancer:8.92e-5 (favourable), Head and neck cancer:2.93e-4 (favourable) Expressed in all Mixed prostate: 23.1 Mixed +MFAP5 MAGP2, MP25 ENSG00000197614 Microfibrillar associated protein 5 12 8637346-8662888 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA010553 Enhanced Urothelial cancer:5.81e-4 (unfavourable), Stomach cancer:6.87e-4 (unfavourable) Mixed Expressed in all smooth muscle: 207.1 Cell line enhanced BEWO: 166.7;EFO-21: 142.4 +MYH6 ENSG00000197616 Myosin heavy chain 6 14 23381990-23408277 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001239, HPA001349, CAB075723, CAB075724, CAB075725 Enhanced Tissue enriched Tissue enriched 96 heart muscle: 1838.3 skeletal muscle: 19.1 Cell line enriched 33 NTERA-2: 4.6 +ZNF615 FLJ33710 ENSG00000197619 Zinc finger protein 615 19 51991332-52008230 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA052422 Uncertain Approved Nucleoli
Mitochondria Urothelial cancer:2.98e-4 (favourable) Expressed in all Mixed prostate: 28.7 Mixed +CXorf40A CXorf40, EOLA1 ENSG00000197620 Chromosome X open reading frame 40A X 149540355-149550510 Predicted intracellular proteins Evidence at protein level HPA060897 Approved Expressed in all Expressed in all adrenal gland: 69.6 Expressed in all +CDC42SE1 SCIP1, SPEC1 ENSG00000197622 CDC42 small effector 1 1 151050971-151070325 Predicted intracellular proteins Evidence at protein level HPA027634 Approved Supported Plasma membrane Renal cancer:2.19e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 119.4 Expressed in all +MPEG1 MPG1 ENSG00000197629 Macrophage expressed 1 11 59208510-59212951 Predicted membrane proteins, Transporters Evidence at protein level HPA046801 Approved Expressed in all Tissue enhanced spleen: 283.2 appendix: 152.1 Not detected +SERPINB2 HsT1201, PAI2, PLANH2 ENSG00000197632 Serpin family B member 2 18 63871692-63903890 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA015480 Supported Urothelial cancer:1.55e-5 (unfavourable) Tissue enhanced Group enriched 6 esophagus: 260.7;placenta: 70.3;skin: 105.8;tonsil: 72.9 bone marrow: 22.2 Group enriched 6 HaCaT: 611.4;U-138 MG: 792.9;U-2197: 1151.1 +DPP4 ADCP2, CD26, DPPIV ENSG00000197635 Dipeptidyl peptidase 4 2 161992241-162074542 CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB045970 Enhanced Renal cancer:1.35e-6 (favourable), Prostate cancer:1.98e-4 (unfavourable), Thyroid cancer:4.99e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 550.6 placenta: 169.1 Cell line enhanced ASC diff: 115.0;ASC TERT1: 118.1;BJ hTERT+: 131.1;RPTEC TERT1: 175.8 +SERPINB13 headpin, HUR7, hurpin, PI13 ENSG00000197641 Serpin family B member 13 18 63586989-63604639 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052630, HPA057129 Enhanced Approved Nuclear speckles
Cytosol Tissue enhanced Tissue enriched 9 esophagus: 184.6 tonsil: 20.7 Group enriched 137 HaCaT: 177.0;hTCEpi: 54.2 +PDCD1LG2 B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2 ENSG00000197646 Programmed cell death 1 ligand 2 9 5510570-5571254 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level HPA013411 Approved Approved Cytosol Renal cancer:1.15e-4 (unfavourable) Mixed Tissue enhanced spleen: 21.5 lymph node: 12.0 Cell line enhanced BJ: 62.0;BJ hTERT+: 93.1;HDLM-2: 83.9 +ZNF433 FLJ40981 ENSG00000197647 Zinc finger protein 433 19 12014732-12035741 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA073724 Uncertain Approved Nuclear bodies Renal cancer:8.33e-15 (favourable) Expressed in all Expressed in all testis: 51.5 Mixed +CCER1 C12orf12, MGC26598 ENSG00000197651 Coiled-coil glutamate rich protein 1 12 90905622-90955176 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 341 testis: 34.0 all non-specific tissues: 0.0 Not detected +DNAH10 FLJ43808 ENSG00000197653 Dynein axonemal heavy chain 10 12 123762188-123936206 Predicted intracellular proteins Evidence at protein level HPA039066 Enhanced Tissue enhanced Group enriched 6 fallopian tube: 5.6;testis: 5.6 lung: 0.9 Not detected +SLC22A24 MGC34821, NET46 ENSG00000197658 Solute carrier family 22 member 24 11 63079940-63144221 Predicted membrane proteins, Transporters Evidence at transcript level HPA045015 Uncertain Tissue enriched Tissue enriched 47 kidney: 4.6 all non-specific tissues: 0.0 Not detected +KRTAP26-1 ENSG00000197683 Keratin associated protein 26-1 21 30319124-30320316 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 19 placenta: 1.9 testis: 0.1 Not detected +SPTAN1 ENSG00000197694 Spectrin alpha, non-erythrocytic 1 9 128552558-128633662 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004581, HPA007927 Enhanced Approved Vesicles
Microtubules Renal cancer:1.84e-12 (favourable) Expressed in all Expressed in all cerebral cortex: 201.9 Expressed in all +NMB MGC17211, MGC2277, MGC3936 ENSG00000197696 Neuromedin B 15 84655129-84658563 Predicted secreted proteins Evidence at protein level CAB019302 Approved Approved Nucleus
Vesicles
Plasma membrane Renal cancer:2.25e-4 (unfavourable), Glioma:5.07e-4 (favourable) Expressed in all Tissue enhanced adipose tissue: 46.2;cerebral cortex: 47.2 thyroid gland: 14.8 Cell line enhanced A-431: 46.7 +PARVA FLJ10793, FLJ12254, MXRA2 ENSG00000197702 Parvin alpha 11 12377185-12530801 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA005964 Approved Supported Actin filaments
Focal adhesion sites
Cytosol Endometrial cancer:1.76e-4 (favourable), Lung cancer:8.19e-4 (unfavourable) Expressed in all Mixed smooth muscle: 145.8 Mixed +KLHL14 KIAA1384 ENSG00000197705 Kelch like family member 14 18 32672671-32773062 Predicted intracellular proteins Evidence at protein level HPA024777 Uncertain Supported Actin filaments
Cytosol Group enriched Tissue enhanced parathyroid gland: 19.3;seminal vesicle: 17.9;thyroid gland: 23.0 spleen: 11.7 Cell line enhanced Hep G2: 10.5;REH: 3.8;RPTEC TERT1: 6.3;SCLC-21H: 3.7 +OR6C74 ENSG00000197706 Olfactory receptor family 6 subfamily C member 74 12 55247198-55248302 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +FAM114A1 Noxp20 ENSG00000197712 Family with sequence similarity 114 member A1 4 38867677-38945739 Predicted intracellular proteins Evidence at protein level HPA067948, HPA069104, HPA069701 Uncertain Enhanced Nucleus
Golgi apparatus
Cytosol Renal cancer:3.63e-6 (unfavourable) Expressed in all Expressed in all smooth muscle: 88.5 Cell line enhanced fHDF/TERT166: 212.1 +RPE ENSG00000197713 Ribulose-5-phosphate-3-epimerase 2 210002565-210022259 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036498, HPA036499 Approved Liver cancer:1.42e-6 (unfavourable), Pancreatic cancer:7.00e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 49.6 Expressed in all +ZNF460 HZF8, ZNF272 ENSG00000197714 Zinc finger protein 460 19 57280051-57293569 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053004, HPA066506 Uncertain Approved Nucleoplasm Mixed Mixed adrenal gland: 6.3 Cell line enhanced Karpas-707: 9.7 +CR1L ENSG00000197721 Complement C3b/C4b receptor 1 like 1 207645113-207738416 Predicted secreted proteins Evidence at protein level HPA049348 Approved Tissue enhanced Not detected bone marrow: 0.8 Group enriched 8 HEL: 1.1;HMC-1: 2.6;K-562: 1.4 +PHF2 CENP-35, JHDM1E, KDM7C, KIAA0662 ENSG00000197724 PHD finger protein 2 9 93576407-93679587 Predicted intracellular proteins Evidence at protein level HPA010831 Approved Renal cancer:1.12e-5 (favourable), Colorectal cancer:9.34e-4 (unfavourable) Expressed in all Expressed in all endometrium: 30.7 Expressed in all +RPS26 S26 ENSG00000197728 Ribosomal protein S26 12 56041853-56044675 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043961, HPA055803 Uncertain Enhanced Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all thyroid gland: 824.8 Expressed in all +C14orf178 FLJ25976 ENSG00000197734 Chromosome 14 open reading frame 178 14 77760830-77769742 Predicted intracellular proteins Evidence at transcript level HPA062581 Uncertain Not detected Mixed skin: 2.1 Mixed +SCGB1D4 IIS ENSG00000197745 Secretoglobin family 1D member 4 11 62296277-62299064 Predicted secreted proteins Evidence at protein level Tissue enriched Group enriched 6 cervix, uterine: 76.0;epididymis: 55.4;fallopian tube: 74.8 endometrium: 11.8 Not detected +PSAP GLBA, SAP1 ENSG00000197746 Prosaposin 10 71816298-71851375 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA004426, CAB004647 Enhanced Supported Vesicles Expressed in all Expressed in all cerebral cortex: 1912.4 Expressed in all +S100A10 42C, ANX2LG, CAL1L, CLP11, P11 ENSG00000197747 S100 calcium binding protein A10 1 151982915-151994390 Predicted membrane proteins, Transporters Evidence at protein level HPA003340, CAB025484 Enhanced Approved Mitochondria Renal cancer:3.80e-8 (unfavourable), Lung cancer:2.66e-5 (unfavourable), Liver cancer:1.00e-4 (unfavourable), Head and neck cancer:3.33e-4 (unfavourable), Urothelial cancer:3.84e-4 (unfavourable), Pancreatic cancer:3.88e-4 (unfavourable) Expressed in all Expressed in all esophagus: 974.3 Mixed +CFAP43 bA373N18.2, C10orf79, FLJ22944, FLJ36006, WDR96 ENSG00000197748 Cilia and flagella associated protein 43 10 104129888-104232362 Predicted intracellular proteins Evidence at protein level Mixed Group enriched 7 fallopian tube: 78.0;testis: 103.2 lung: 12.5 Cell line enhanced CAPAN-2: 3.7;U-266/70: 2.5 +LHFPL5 DFNB67, dJ510O8.8, MGC33835, Tmhs ENSG00000197753 Lipoma HMGIC fusion partner-like 5 6 35805293-35833874 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA055110 Uncertain Not detected Tissue enhanced epididymis: 10.8 bone marrow: 4.2 Mixed +RPL37A L37A ENSG00000197756 Ribosomal protein L37a 2 216498189-216579180 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA065327 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:1.14e-4 (unfavourable) Expressed in all Expressed in all ovary: 4523.8 Expressed in all +HOXC6 HOX3, HOX3C ENSG00000197757 Homeobox C6 12 53990624-54030823 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054981 Supported Nucleoplasm
Cytosol Renal cancer:3.55e-6 (unfavourable) Mixed Mixed epididymis: 22.3 Cell line enhanced AN3-CA: 85.1;HDLM-2: 73.7 +TXNRD3 TGR, TR2, TRXR3 ENSG00000197763 Thioredoxin reductase 3 3 126607052-126655155 Predicted intracellular proteins Evidence at protein level CAB020802, HPA036109 Uncertain Enhanced Nucleoplasm
Cytosol Renal cancer:2.72e-4 (favourable), Pancreatic cancer:2.86e-4 (unfavourable), Endometrial cancer:3.35e-4 (unfavourable) Expressed in all Tissue enhanced testis: 43.4 parathyroid gland: 18.4 Mixed +CFD ADN, DF, PFD ENSG00000197766 Complement factor D 19 859643-863630 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA052799 Uncertain Plasma membrane Pancreatic cancer:1.77e-4 (favourable), Renal cancer:7.09e-4 (unfavourable) Expressed in all Tissue enriched 7 adipose tissue: 378.5 breast: 52.5 Group enriched 6 ASC diff: 82.6;THP-1: 121.6 +STPG3 C9orf173, FLJ40246 ENSG00000197768 Sperm-tail PG-rich repeat containing 3 9 137251261-137253483 Predicted intracellular proteins Evidence at transcript level HPA044352 Uncertain Vesicles Mixed Tissue enriched 7 testis: 27.7 duodenum: 3.9 Cell line enhanced HDLM-2: 3.0;T-47d: 1.8 +MAP1LC3C ATG8J ENSG00000197769 Microtubule associated protein 1 light chain 3 gamma 1 241995490-241999073 Predicted intracellular proteins Evidence at protein level HPA072670 Supported Cytoplasmic bodies Endometrial cancer:1.34e-7 (unfavourable) Mixed Tissue enhanced breast: 12.7;placenta: 16.1 lung: 8.1 Cell line enhanced AF22: 6.0;ASC TERT1: 3.9;BEWO: 3.7;EFO-21: 3.2 +MCMBP C10orf119, FLJ13081, MCM-BP ENSG00000197771 Minichromosome maintenance complex binding protein 10 119829404-119892556 Predicted intracellular proteins Evidence at protein level CAB013792, HPA038481 Uncertain Enhanced Nucleoplasm Pancreatic cancer:2.20e-4 (unfavourable), Renal cancer:6.18e-4 (unfavourable) Expressed in all Expressed in all placenta: 63.6 Expressed in all +EME2 FLJ00151, SLX2B ENSG00000197774 Essential meiotic structure-specific endonuclease subunit 2 16 1773207-1781708 Predicted intracellular proteins Evidence at protein level HPA045770 Uncertain Renal cancer:6.76e-7 (unfavourable), Urothelial cancer:6.32e-5 (favourable), Head and neck cancer:2.86e-4 (favourable) Expressed in all Mixed prostate: 1.0 Cell line enhanced HEK 293: 8.1;SCLC-21H: 4.3 +KLHDC1 MST025 ENSG00000197776 Kelch domain containing 1 14 49693105-49753152 Predicted intracellular proteins Evidence at protein level HPA020461 Approved Supported Cytosol Pancreatic cancer:1.94e-4 (favourable) Mixed Mixed endometrium: 9.7 Cell line enhanced ASC diff: 3.8;ASC TERT1: 3.7 +ZNF81 HFZ20, MRX45 ENSG00000197779 Zinc finger protein 81 X 47836902-48002561 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA001689 Approved Mixed Mixed parathyroid gland: 9.9 Mixed +TAF13 TAF2K, TAFII18 ENSG00000197780 TATA-box binding protein associated factor 13 1 109062486-109076002 Predicted intracellular proteins Evidence at protein level HPA044492 Approved Enhanced Nucleus
Nucleoli Liver cancer:8.74e-6 (unfavourable), Ovarian cancer:2.42e-5 (favourable) Expressed in all Expressed in all smooth muscle: 50.5 Expressed in all +ZNF780A ZNF780 ENSG00000197782 Zinc finger protein 780A 19 40069152-40090938 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003311 Uncertain Approved Nucleus
Centrosome Urothelial cancer:9.30e-4 (favourable) Expressed in all Mixed parathyroid gland: 8.4 Expressed in all +ATAD3A FLJ10709 ENSG00000197785 ATPase family, AAA domain containing 3A 1 1512151-1534687 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA058968, HPA064867, HPA065305 Approved Supported Mitochondria Liver cancer:5.90e-5 (unfavourable) Expressed in all Expressed in all appendix: 16.1 Expressed in all +OR5B17 OR5B20P ENSG00000197786 Olfactory receptor family 5 subfamily B member 17 11 58358124-58359069 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR52M1 OR52M1P ENSG00000197790 Olfactory receptor family 52 subfamily M member 1 11 4545191-4546144 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +FAM118B FLJ21103 ENSG00000197798 Family with sequence similarity 118 member B 11 126211414-126262986 Predicted intracellular proteins Evidence at protein level HPA041644, HPA042100 Approved Approved Intermediate filaments
Cytosol Liver cancer:6.67e-7 (unfavourable) Expressed in all Expressed in all testis: 37.8 Expressed in all +ZNF461 GIOT-1, MGC33911 ENSG00000197808 Zinc finger protein 461 19 36637192-36666853 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA021139 Uncertain Approved Nucleus
Nucleoli
Golgi apparatus Endometrial cancer:3.64e-4 (unfavourable) Expressed in all Mixed thyroid gland: 6.2 Mixed +CCDC180 BDAG1, C9orf174, DKFZp434I2420, KIAA1529 ENSG00000197816 Coiled-coil domain containing 180 9 97307304-97378524 Predicted intracellular proteins Evidence at protein level Not detected Group enriched 6 fallopian tube: 15.8;testis: 37.9 lung: 4.8 Cell line enhanced HDLM-2: 3.9;U-266/70: 4.4 +SLC9A8 KIAA0939, NHE8 ENSG00000197818 Solute carrier family 9 member A8 20 49812713-49892242 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB033682 Approved Expressed in all Expressed in all bone marrow: 13.2 Expressed in all +OCLN PPP1R115 ENSG00000197822 Occludin 5 69492292-69558104 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA005933, CAB013075, CAB068212, CAB068213, CAB068214 Enhanced Supported Plasma membrane
Cell Junctions Renal cancer:6.59e-11 (favourable) Mixed Tissue enhanced thyroid gland: 78.7 lung: 39.8 Cell line enhanced CAPAN-2: 60.2;HaCaT: 48.8 +C4orf22 ENSG00000197826 Chromosome 4 open reading frame 22 4 80335720-80963756 Predicted intracellular proteins Evidence at transcript level HPA043383 Approved Approved Plasma membrane
Cytosol Not detected Group enriched 23 fallopian tube: 30.6;testis: 47.6 lung: 1.7 Cell line enhanced A-431: 1.1;BJ: 1.4;SCLC-21H: 1.2 +HIST4H4 MGC24116 ENSG00000197837 Histone cluster 4 H4 12 14767999-14771131 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB011503, CAB037279, HPA042201 Supported Supported Nucleoplasm Mixed Mixed prostate: 7.2 Cell line enhanced CAPAN-2: 4.1 +CYP2A13 CPAD, CYP2A ENSG00000197838 Cytochrome P450 family 2 subfamily A member 13 19 41088472-41096195 Enzymes, Predicted secreted proteins Evidence at protein level HPA046713, HPA047262 Supported Tissue enriched Not detected liver,testis: 0.3 Not detected +ZNF181 HHZ181, MGC44316 ENSG00000197841 Zinc finger protein 181 19 34734155-34745378 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043701, HPA062305 Uncertain Approved Nucleus Pancreatic cancer:1.05e-4 (favourable), Melanoma:2.60e-4 (unfavourable), Urothelial cancer:5.45e-4 (favourable) Expressed in all Expressed in all ovary: 21.5 Mixed +OR8G1 HSTPCR25, OR8G1P, TPCR25 ENSG00000197849 Olfactory receptor family 8 subfamily G member 1 (gene/pseudogene) 11 124249676-124250611 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.6 Not detected +FAM212B C1orf183, FLJ31105, INKA2 ENSG00000197852 Family with sequence similarity 212 member B 1 111680630-111755824 Predicted intracellular proteins Evidence at protein level HPA027809, HPA027811 Approved Approved Nucleus Head and neck cancer:4.51e-5 (favourable) Tissue enhanced Mixed cerebral cortex: 16.7 Cell line enhanced hTEC/SVTERT24-B: 37.7;U-87 MG: 71.6 +ZNF44 KOX7, ZNF504, ZNF55, ZNF58 ENSG00000197857 Zinc finger protein 44 19 12224686-12294887 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003146 Supported Approved Nucleoplasm
Microtubules
Cytosol Urothelial cancer:9.21e-6 (favourable), Lung cancer:7.54e-4 (favourable), Head and neck cancer:8.74e-4 (favourable) Expressed in all Mixed skin: 8.6 Mixed +GPAA1 GAA1, hGAA1 ENSG00000197858 Glycosylphosphatidylinositol anchor attachment 1 8 144082590-144086216 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all parathyroid gland: 70.1 Expressed in all +ADAMTSL2 KIAA0605 ENSG00000197859 ADAMTS like 2 9 133532164-133575519 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045634, HPA053812 Approved Approved Vesicles Colorectal cancer:5.01e-4 (unfavourable), Pancreatic cancer:6.70e-4 (favourable) Expressed in all Tissue enhanced adrenal gland: 29.0 kidney: 11.2 Cell line enhanced Hep G2: 4.9;RPMI-8226: 6.9;SH-SY5Y: 31.9 +SGTB FLJ39002, Sgt2 ENSG00000197860 Small glutamine rich tetratricopeptide repeat containing beta 5 65665928-65723035 Predicted intracellular proteins Evidence at protein level HPA044689, HPA063674 Enhanced Uncertain Nucleus Expressed in all Tissue enhanced cerebral cortex: 52.0 appendix: 10.4 Expressed in all +ZNF790 FLJ20350, MGC62100 ENSG00000197863 Zinc finger protein 790 19 36817428-36850787 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA056134, HPA060288 Uncertain Approved Nucleoli Endometrial cancer:7.66e-4 (unfavourable) Expressed in all Mixed testis: 20.5 Mixed +PRB3 PRG ENSG00000197870 Proline rich protein BstNI subfamily 3 12 11265924-11269805 Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enriched 3949 salivary gland: 5770.7 skin: 1.4 Cell line enriched 5 NTERA-2: 2.2 +FAM49A DKFZP566A1524, FLJ11080 ENSG00000197872 Family with sequence similarity 49 member A 2 16549459-16666331 Predicted intracellular proteins Evidence at protein level CAB017847, HPA060398 Approved Approved Nucleoplasm Renal cancer:1.83e-6 (unfavourable), Urothelial cancer:4.46e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 81.4 thyroid gland: 68.3 Cell line enhanced HMC-1: 46.7;HUVEC TERT2: 36.0;RH-30: 92.5 +MYO1C myr2 ENSG00000197879 Myosin IC 17 1464098-1492812 Predicted intracellular proteins, Transporters Evidence at protein level HPA001768, HPA005924, CAB037023 Enhanced Enhanced Nuclear bodies
Plasma membrane Lung cancer:5.22e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 192.4 Mixed +MDS2 ENSG00000197880 Myelodysplastic syndrome 2 translocation associated 1 23581495-23640568 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at transcript level HPA052999 Uncertain Tissue enhanced Tissue enhanced lymph node: 7.7;tonsil: 4.0 spleen: 2.9 Cell line enhanced Daudi: 1.0;U-266/70: 1.0;U-698: 3.4 +NKIRAS1 kappaB-Ras1, KBRAS1 ENSG00000197885 NFKB inhibitor interacting Ras like 1 3 23891660-23946591 Predicted intracellular proteins Evidence at protein level HPA062521 Approved Microtubules Renal cancer:7.71e-13 (favourable), Lung cancer:3.69e-4 (favourable), Endometrial cancer:8.31e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 50.4 Expressed in all +OR1S2 ENSG00000197887 Olfactory receptor family 1 subfamily S member 2 11 58203202-58204181 G-protein coupled receptors, Predicted membrane proteins No evidence HPA049304 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +UGT2B17 ENSG00000197888 UDP glucuronosyltransferase family 2 member B17 4 68537184-68568527 Enzymes, Predicted membrane proteins Evidence at protein level HPA045108 Supported Group enriched Tissue enhanced colon: 372.4;duodenum: 371.2;small intestine: 522.5 rectum: 151.7 Cell line enhanced RPMI-8226: 1.2 +MEIG1 bA2K17.3, SPATA39 ENSG00000197889 Meiosis/spermiogenesis associated 1 10 14959439-14988050 Predicted intracellular proteins Evidence at transcript level HPA044594 Uncertain Mixed Group enriched 12 fallopian tube: 6.7;testis: 13.0 cerebral cortex: 0.8 Cell line enhanced HDLM-2: 5.1 +SLC22A12 OAT4L, RST, URAT1 ENSG00000197891 Solute carrier family 22 member 12 11 64590641-64602353 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA024575 Enhanced Renal cancer:2.63e-4 (favourable) Group enriched Tissue enriched 198 kidney: 105.0 adipose tissue: 0.5 Not detected +KIF13B GAKIN, KIAA0639 ENSG00000197892 Kinesin family member 13B 8 29067279-29263124 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025023, HPA049655 Enhanced Renal cancer:0.00e+0 (favourable), Pancreatic cancer:4.77e-4 (unfavourable), Head and neck cancer:6.26e-4 (favourable), Colorectal cancer:8.92e-4 (favourable) Expressed in all Tissue enriched 10 parathyroid gland: 208.8 kidney: 20.2 Mixed +NRAP ENSG00000197893 Nebulin related anchoring protein 10 113588716-113664127 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037953, HPA037954 Approved Group enriched Group enriched 17 heart muscle: 210.6;skeletal muscle: 814.0 prostate: 30.3 Not detected +ADH5 ADH-3, ADHX, FDH, GSNOR ENSG00000197894 Alcohol dehydrogenase 5 (class III), chi polypeptide 4 99070978-99088801 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044578, HPA061919 Approved Renal cancer:4.58e-10 (favourable), Endometrial cancer:9.90e-5 (favourable), Melanoma:3.54e-4 (unfavourable) Expressed in all Expressed in all endometrium: 198.2 Expressed in all +SLC22A6 OAT1, PAHT, ROAT1 ENSG00000197901 Solute carrier family 22 member 6 11 62936385-62984983 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA074559, CAB075704 Enhanced Tissue enriched Tissue enriched 64 kidney: 200.2 cerebral cortex: 3.1 Not detected +HIST1H2BK H2BFAiii, H2BFT ENSG00000197903 Histone cluster 1 H2B family member k 6 27146418-27146798 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Renal cancer:5.77e-5 (unfavourable) Expressed in all Expressed in all prostate: 106.2 Expressed in all +TEAD4 EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1 ENSG00000197905 TEA domain transcription factor 4 12 2959330-3040673 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056896 Uncertain Supported Nucleoplasm Renal cancer:9.78e-9 (unfavourable) Tissue enriched Tissue enhanced skeletal muscle: 38.8 thyroid gland: 17.8 Cell line enhanced HBEC3-KT: 263.0 +SPG7 CAR, CMAR, SPG5C ENSG00000197912 SPG7, paraplegin matrix AAA peptidase subunit 16 89490917-89557768 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Endometrial cancer:2.22e-4 (favourable), Urothelial cancer:4.25e-4 (favourable), Pancreatic cancer:4.91e-4 (favourable) Expressed in all Expressed in all thyroid gland: 52.2 Expressed in all +HRNR FLG3, S100A16, S100a18 ENSG00000197915 Hornerin 1 152212082-152224193 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031469 Uncertain Approved Mitochondria Tissue enhanced Not detected skin: 0.7 Cell line enhanced NTERA-2: 1.9 +IFNA1 IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA@, IFNA13 ENSG00000197919 Interferon alpha 1 9 21440454-21441316 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected urinary bladder: 0.2 Cell line enhanced HeLa: 1.4 +HES5 bHLHb38 ENSG00000197921 Hes family bHLH transcription factor 5 1 2528745-2530245 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA065458, HPA076164 Enhanced Approved Nucleoplasm
Nuclear speckles
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 1.8 skin: 0.9 Cell line enhanced HaCaT: 1.1 +ZNF677 MGC48625 ENSG00000197928 Zinc finger protein 677 19 53235381-53254898 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023106, HPA024796 Approved Approved Nucleus
Centrosome Mixed Expressed in all testis: 71.1 Cell line enhanced NTERA-2: 30.7 +ERO1A ERO1-alpha, Ero1alpha, ERO1L ENSG00000197930 Endoplasmic reticulum oxidoreductase 1 alpha 14 52639916-52695900 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026653, HPA030053, CAB034294 Enhanced Renal cancer:6.54e-9 (unfavourable), Lung cancer:1.10e-5 (unfavourable), Pancreatic cancer:2.27e-4 (unfavourable), Liver cancer:7.59e-4 (unfavourable), Cervical cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all esophagus: 181.5 Expressed in all +ZNF823 HSZFP36 ENSG00000197933 Zinc finger protein 823 19 11721265-11739009 Predicted intracellular proteins, Transcription factors Evidence at transcript level Head and neck cancer:6.76e-5 (favourable), Renal cancer:4.49e-4 (favourable), Stomach cancer:5.05e-4 (favourable) Expressed in all Mixed parathyroid gland: 12.5 Mixed +ZNF311 ENSG00000197935 Zinc finger protein 311 6 28994785-29005316 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA050541 Uncertain Mixed Not detected fallopian tube: 0.4 Not detected +ZNF347 ZNF1111 ENSG00000197937 Zinc finger protein 347 19 53124072-53159075 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023448 Uncertain Approved Microtubules Mixed Expressed in all spleen: 13.3 Mixed +OR5H2 ENSG00000197938 Olfactory receptor family 5 subfamily H member 2 3 98282888-98283832 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +PLCG2 ENSG00000197943 Phospholipase C gamma 2 16 81739097-81962693 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004280, HPA020099, HPA020100 Enhanced Approved Vesicles Renal cancer:4.88e-4 (favourable), Head and neck cancer:6.71e-4 (favourable) Expressed in all Tissue enhanced lymph node: 78.9 tonsil: 65.8 Cell line enhanced Daudi: 130.7;HMC-1: 74.1;U-698: 278.1 +FCHSD1 FLJ00007 ENSG00000197948 FCH and double SH3 domains 1 5 141639302-141651419 Predicted intracellular proteins Evidence at protein level HPA043795 Approved Approved Nucleoplasm
Cytosol Renal cancer:6.19e-6 (unfavourable), Urothelial cancer:1.21e-4 (favourable), Testis cancer:4.77e-4 (unfavourable), Breast cancer:8.62e-4 (favourable) Expressed in all Mixed parathyroid gland: 41.1 Mixed +ZNF71 Cos26, EZFIT ENSG00000197951 Zinc finger protein 71 19 56595264-56626481 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018124 Uncertain Approved Nucleus
Nucleoli Expressed in all Mixed cerebral cortex: 5.3 Mixed +AADACL2 MGC72001 ENSG00000197953 Arylacetamide deacetylase like 2 3 151733916-151761339 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 14 skin: 31.1 breast: 2.3 Not detected +S100A6 2A9, CABP, CACY, PRA ENSG00000197956 S100 calcium binding protein A6 1 153534599-153536244 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002601, HPA007575, CAB040549, CAB047354 Enhanced Enhanced Plasma membrane
Cytosol Urothelial cancer:7.56e-4 (favourable) Expressed in all Expressed in all lung: 1678.1 Cell line enhanced RPTEC TERT1: 7409.7 +RPL12 L12 ENSG00000197958 Ribosomal protein L12 9 127447674-127451405 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003403 Approved Approved Golgi apparatus Renal cancer:7.42e-7 (unfavourable), Head and neck cancer:5.66e-4 (unfavourable) Expressed in all Expressed in all ovary: 3674.5 Expressed in all +DNM3 KIAA0820 ENSG00000197959 Dynamin 3 1 171841498-172418466 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064121 Approved Golgi apparatus Mixed Tissue enhanced cerebral cortex: 41.1 adrenal gland: 15.6 Cell line enhanced HEL: 20.5;RPTEC TERT1: 14.4;U-251 MG: 11.7 +ZNF121 D19S204, ZHC32, ZNF20 ENSG00000197961 Zinc finger protein 121 19 9560353-9584533 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054961 Uncertain Uncertain Nucleoplasm
Nucleoli
Centrosome Urothelial cancer:5.75e-5 (favourable), Ovarian cancer:6.59e-5 (favourable), Renal cancer:1.01e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.1 Expressed in all +MPZL1 FLJ21047, PZR ENSG00000197965 Myelin protein zero like 1 1 167721192-167791919 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026966, HPA063538 Approved Supported Vesicles
Plasma membrane Renal cancer:3.99e-7 (unfavourable), Liver cancer:4.27e-6 (unfavourable), Lung cancer:3.98e-4 (unfavourable), Thyroid cancer:8.08e-4 (unfavourable) Expressed in all Expressed in all breast: 111.6 Expressed in all +VPS13A CHAC, KIAA0986 ENSG00000197969 Vacuolar protein sorting 13 homolog A 9 77177353-77421541 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021652, HPA021662 Enhanced Expressed in all Expressed in all skin: 40.2 Expressed in all +MBP ENSG00000197971 Myelin basic protein 18 76978827-77133683 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002300, HPA049222, HPA064368 Enhanced Supported Approved Plasma membrane Renal cancer:4.48e-12 (favourable) Group enriched Tissue enriched 29 cerebral cortex: 2930.7 parathyroid gland: 99.8 Cell line enhanced HL-60: 79.4;SK-MEL-30: 158.4 +AKAP17A 721P, CCDC133, CXYorf3, DXYS155E, MGC39904, SFRS17A, XE7, XE7Y ENSG00000197976 A-kinase anchoring protein 17A X 1591593-1602514 Predicted intracellular proteins Evidence at protein level HPA043247, HPA051020 Enhanced Supported Nuclear speckles
Cytosol Renal cancer:3.52e-7 (unfavourable), Urothelial cancer:1.11e-5 (favourable), Pancreatic cancer:2.42e-4 (favourable), Endometrial cancer:3.40e-4 (favourable) Expressed in all Expressed in all spleen: 60.4 Expressed in all +ELOVL2 Ssc2 ENSG00000197977 ELOVL fatty acid elongase 2 6 10980759-11044314 Enzymes, Predicted membrane proteins Evidence at protein level Breast cancer:6.73e-5 (favourable) Group enriched Tissue enhanced liver: 27.6;parathyroid gland: 36.7;placenta: 50.2 cerebral cortex: 22.8 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 29.1;HBF TERT88: 28.0;RH-30: 30.7 +GOLGA6L9 GOLGA6L20 ENSG00000197978 Golgin A6 family-like 9 15 82430018-82439153 Predicted intracellular proteins Evidence at transcript level Mixed Not detected stomach,testis: 0.9 Cell line enhanced AN3-CA: 3.7;HDLM-2: 3.3 +LEKR1 FLJ16641 ENSG00000197980 Leucine, glutamate and lysine rich 1 3 156825481-157046129 Predicted intracellular proteins Evidence at protein level HPA044039 Uncertain Not detected Tissue enhanced testis: 27.3 fallopian tube: 6.7 Mixed +C1orf122 FLJ45459 ENSG00000197982 Chromosome 1 open reading frame 122 1 37806979-37809454 Predicted intracellular proteins Evidence at protein level Urothelial cancer:4.81e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 52.7 Expressed in all +RP11-310K10.1 ENSG00000197991 13 61409858-61427849 Predicted membrane proteins No evidence HPA062669 Approved Vesicles
Cytokinetic bridge Not detected Not detected testis: 0.5 Not detected +CLEC9A CD370, DNGR-1, HEEE9341, UNQ9341 ENSG00000197992 C-type lectin domain family 9 member A 12 10030677-10066027 Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enhanced lymph node: 7.8;spleen: 6.6 testis: 5.5 Not detected +KEL CD238, ECE3 ENSG00000197993 Kell blood group, metallo-endopeptidase 7 142941114-142962681 Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced bone marrow: 14.5;testis: 19.5 lymph node: 6.4 Group enriched 14 HEL: 12.2;K-562: 10.7 +NOL8 C9orf34, FLJ20736, Nop132 ENSG00000198000 Nucleolar protein 8 9 92297358-92325636 Predicted intracellular proteins Evidence at protein level HPA044440, HPA062922 Uncertain Supported Nucleoli Renal cancer:1.02e-5 (unfavourable), Liver cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.4 Expressed in all +IRAK4 NY-REN-64 ENSG00000198001 Interleukin 1 receptor associated kinase 4 12 43758944-43789543 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB016685, CAB022077 Uncertain Approved Nucleoli
Microtubules
Cytosol Endometrial cancer:3.46e-5 (favourable), Urothelial cancer:4.42e-5 (favourable) Expressed in all Mixed lymph node: 20.3 Expressed in all +CCDC151 MGC20983 ENSG00000198003 Coiled-coil domain containing 151 19 11420604-11435782 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044184, HPA054626 Enhanced Approved Nucleoplasm Mixed Tissue enhanced fallopian tube: 13.4;parathyroid gland: 6.8;testis: 7.5 cerebral cortex: 2.0 Cell line enhanced SCLC-21H: 2.4;T-47d: 4.5 +DLGAP2 DAP-2 ENSG00000198010 DLG associated protein 2 8 737596-1708474 Nuclear receptors, Predicted intracellular proteins Evidence at protein level HPA030320 Uncertain Not detected Group enriched 10 cerebral cortex: 2.0;testis: 6.1 thyroid gland: 0.4 Not detected +MRPL42 HSPC204, MRP-L31, MRPL31, MRPS32, PTD007, RPML31 ENSG00000198015 Mitochondrial ribosomal protein L42 12 93467488-93516213 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA039398 Approved Supported Plasma membrane
Mitochondria Liver cancer:7.49e-4 (unfavourable), Urothelial cancer:8.12e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 57.2 Expressed in all +ENTPD7 FLJ30978, LALP1 ENSG00000198018 Ectonucleoside triphosphate diphosphohydrolase 7 10 99659506-99706240 Predicted membrane proteins Evidence at protein level HPA014351 Uncertain Approved Nucleoplasm Expressed in all Mixed small intestine: 23.7 Mixed +FCGR1B CD64b ENSG00000198019 Fc fragment of IgG receptor Ib 1 121087345-121096310 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enhanced appendix: 27.5;epididymis: 61.7 placenta: 17.0 Cell line enhanced HMC-1: 6.6;NB-4: 12.8;THP-1: 51.9 +SPANXA1 CT11.1, NAP-X, SPAN-Xa, SPAN-Xb, SPANX ENSG00000198021 Sperm protein associated with the nucleus, X-linked, family member A1 X 141583674-141585011 Predicted intracellular proteins Evidence at protein level HPA046423, HPA073647 Supported Supported Nucleoplasm
Vesicles Not detected Tissue enriched 93 testis: 9.2 all non-specific tissues: 0.0 Cell line enhanced U-2 OS: 1.6 +ZNF335 bA465L10.2, NIF-1 ENSG00000198026 Zinc finger protein 335 20 45948653-45972172 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063999, HPA071230 Enhanced Nucleoplasm Renal cancer:2.77e-5 (unfavourable), Liver cancer:1.59e-4 (unfavourable), Head and neck cancer:4.48e-4 (favourable), Prostate cancer:7.04e-4 (unfavourable) Expressed in all Expressed in all skin: 24.6 Expressed in all +ZNF560 FLJ31986 ENSG00000198028 Zinc finger protein 560 19 9466507-9498607 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045439, HPA063209 Supported Nucleoplasm
Plasma membrane Tissue enriched Tissue enriched 9 testis: 11.9 placenta: 1.2 Cell line enhanced HEL: 19.1;NTERA-2: 20.6 +TUBA3C bA408E5.3, TUBA2 ENSG00000198033 Tubulin alpha 3c 13 19173770-19181852 Predicted intracellular proteins Evidence at protein level HPA039247, HPA043684, HPA063394 Uncertain Supported Microtubules Mixed Tissue enriched 2118 testis: 513.8 epididymis: 0.2 Group enriched 51 HDLM-2: 97.4;U-2 OS: 263.4;U-266/70: 63.0;U-266/84: 75.1 +RPS4X CCG2, DXS306, FLJ40595, RPS4, S4, SCAR, SCR10 ENSG00000198034 Ribosomal protein S4, X-linked X 72255679-72277300 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA000857 Supported Renal cancer:4.50e-6 (unfavourable), Thyroid cancer:4.22e-4 (favourable) Expressed in all Expressed in all ovary: 1948.7 Expressed in all +ZNF273 HZF9 ENSG00000198039 Zinc finger protein 273 7 64870172-64930966 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA077549 Approved Nucleoplasm Mixed Mixed testis: 2.9 Mixed +ZNF84 HPF2 ENSG00000198040 Zinc finger protein 84 12 133037292-133063304 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028860 Approved Supported Nucleoplasm Liver cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 33.1 Mixed +MAK16 MAK16L, RBM13 ENSG00000198042 MAK16 homolog 8 33484750-33501260 Predicted intracellular proteins Evidence at protein level HPA044417, HPA050574 Uncertain Supported Nucleoli
Vesicles Liver cancer:1.00e-4 (unfavourable), Renal cancer:3.66e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 12.6 Expressed in all +ZNF667 FLJ14011 ENSG00000198046 Zinc finger protein 667 19 56439325-56478065 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030731, HPA046673 Uncertain Approved Nucleus Mixed Mixed cerebral cortex: 18.3 Cell line enhanced HEL: 11.0;U-138 MG: 14.5 +AVPR1B AVPR3 ENSG00000198049 Arginine vasopressin receptor 1B 1 206109692-206117699 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA075404 Supported Tissue enhanced Not detected stomach: 0.3 Not detected +SIRPA BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2 ENSG00000198053 Signal regulatory protein alpha 20 1894167-1940592 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002776, CAB015122, HPA054437, HPA058511 Enhanced Expressed in all Expressed in all cerebral cortex: 207.9 Cell line enhanced fHDF/TERT166: 110.5 +DSCR8 C21orf65, CT25.1a, CT25.1b, MMA-1a, MMA-1b, MTAG2 ENSG00000198054 Down syndrome critical region 8 21 38121451-38188016 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 7 testis: 33.8 placenta: 4.8 Cell line enhanced BEWO: 6.6;K-562: 6.1;U-266/70: 6.9;U-266/84: 3.5 +GRK6 GPRK6 ENSG00000198055 G protein-coupled receptor kinase 6 5 177403204-177442901 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015327, HPA018903 Approved Approved Mitochondria Liver cancer:5.66e-6 (unfavourable), Pancreatic cancer:1.22e-4 (favourable) Expressed in all Expressed in all bone marrow: 87.5 Expressed in all +PRIM1 ENSG00000198056 Primase (DNA) subunit 1 12 56731596-56752373 Predicted intracellular proteins Evidence at protein level HPA040010 Uncertain Supported Vesicles Liver cancer:2.40e-8 (unfavourable) Expressed in all Expressed in all testis: 21.8 Expressed in all +MARCH5 FLJ20445, MARCH-V, MITOL, RNF153 ENSG00000198060 Membrane associated ring-CH-type finger 5 10 92291163-92353964 Enzymes, Predicted membrane proteins Evidence at protein level HPA056596 Supported Mitochondria Expressed in all Expressed in all thyroid gland: 28.7 Expressed in all +POTEH A26C3, ACTBL1, CT104.7, POTE22 ENSG00000198062 POTE ankyrin domain family member H 22 15690026-15721631 Predicted intracellular proteins Evidence at transcript level HPA042822 Uncertain Tissue enriched Group enriched 36 prostate: 5.7;testis: 1.4 all non-specific tissues: 0.0 Cell line enhanced U-2 OS: 1.1 +NPIPB13 ENSG00000198064 Nuclear pore complex interacting protein family, member B13 16 30222937-30254510 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Not detected Mixed skin: 9.1 Mixed +AKR1B10 AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI ENSG00000198074 Aldo-keto reductase family 1 member B10 7 134527592-134541408 Predicted intracellular proteins Evidence at protein level HPA020280, CAB070163, HPA073633 Enhanced Supported Plasma membrane
Cytosol Renal cancer:4.80e-9 (unfavourable), Colorectal cancer:1.91e-4 (favourable) Tissue enhanced Tissue enhanced duodenum: 635.9;gallbladder: 283.3;small intestine: 387.2;stomach: 414.4 esophagus: 89.8 Group enriched 74 A549: 2731.1;Hep G2: 580.9 +SULT1C4 SULT1C, SULT1C2 ENSG00000198075 Sulfotransferase family 1C member 4 2 108377911-108388057 Predicted intracellular proteins Evidence at protein level HPA034530 Approved Cytosol Renal cancer:9.99e-7 (favourable) Group enriched Tissue enhanced gallbladder: 41.5 ovary: 31.2 Cell line enhanced AF22: 8.6;HUVEC TERT2: 7.8;SH-SY5Y: 42.4 +CYP2A7 CYP2A ENSG00000198077 Cytochrome P450 family 2 subfamily A member 7 19 40875439-40882752 Enzymes, Predicted secreted proteins Evidence at protein level CAB033510, HPA046713, HPA047262 Enhanced Group enriched Tissue enriched 123 liver: 60.9 breast: 0.4 Not detected +ZBTB14 ZFP161, ZNF478 ENSG00000198081 Zinc finger and BTB domain containing 14 18 5289019-5297053 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050758, HPA070819 Uncertain Enhanced Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 28.9 Expressed in all +KRTAP9-9 KAP9.5, KAP9.9, KRTAP9-5 ENSG00000198083 Keratin associated protein 9-9 17 41255384-41256364 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +CD2AP CMS ENSG00000198087 CD2 associated protein 6 47477789-47627263 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003267, HPA003326, CAB004352 Enhanced Enhanced Plasma membrane
Cytosol Pancreatic cancer:5.53e-5 (unfavourable), Urothelial cancer:7.57e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 65.8 Expressed in all +NUP62CL FLJ20130 ENSG00000198088 Nucleoporin 62 C-terminal like X 107123427-107206433 Predicted intracellular proteins Evidence at protein level HPA001884 Approved Cervical cancer:5.66e-5 (favourable), Lung cancer:2.11e-4 (unfavourable) Mixed Tissue enhanced fallopian tube: 27.5 testis: 22.1 Cell line enhanced A549: 19.9;CAPAN-2: 20.6;HeLa: 21.0;K-562: 20.5 +SFI1 KIAA0542, PISD, PPP1R139 ENSG00000198089 SFI1 centrin binding protein 22 31488688-31618586 Predicted intracellular proteins Evidence at protein level Head and neck cancer:1.10e-4 (favourable), Urothelial cancer:1.31e-4 (favourable), Pancreatic cancer:5.80e-4 (favourable) Expressed in all Mixed lymph node: 13.9 Expressed in all +KRTAP4-6 KAP4.15, KAP4.6, KRTAP4-15 ENSG00000198090 Keratin associated protein 4-6 17 41139433-41140487 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +TMPRSS11F FLJ16046 ENSG00000198092 Transmembrane protease, serine 11F 4 68053198-68129880 Enzymes, Predicted membrane proteins Evidence at transcript level HPA026911 Uncertain Group enriched Group enriched 7 esophagus: 16.7;skin: 11.0;tonsil: 3.7 breast: 1.5 Cell line enhanced K-562: 1.4 +ZNF649 FLJ12644 ENSG00000198093 Zinc finger protein 649 19 51889224-51905040 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026541 Uncertain Renal cancer:4.60e-5 (favourable), Melanoma:7.44e-4 (unfavourable) Expressed in all Expressed in all prostate: 33.8 Mixed +ADH4 ADH-2 ENSG00000198099 Alcohol dehydrogenase 4 (class II), pi polypeptide 4 99123657-99157792 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020525 Enhanced Uncertain Nucleus
Cytosol Liver cancer:7.08e-6 (favourable) Tissue enriched Tissue enriched 16 liver: 2628.5 duodenum: 166.3 Cell line enriched 7 Hep G2: 15.2 +OR2T6 OR2T6P, OR2T9, OST703 ENSG00000198104 Olfactory receptor family 2 subfamily T member 6 1 248387609-248388535 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF248 bA162G10.3 ENSG00000198105 Zinc finger protein 248 10 37776526-37858106 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018237, HPA018287, HPA018455 Uncertain Approved Nucleoplasm Lung cancer:1.04e-4 (favourable), Pancreatic cancer:1.22e-4 (favourable), Renal cancer:2.25e-4 (unfavourable), Prostate cancer:6.71e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 25.9 Expressed in all +CHSY3 CHSY-2, CSS3 ENSG00000198108 Chondroitin sulfate synthase 3 5 129904472-130186634 Enzymes, Predicted secreted proteins Evidence at protein level HPA044612 Uncertain Mixed Tissue enhanced cervix, uterine: 7.2 gallbladder: 4.5 Cell line enhanced ASC diff: 9.0;ASC TERT1: 8.1;U-138 MG: 14.0 +TOR4A C9orf167, FLJ20245 ENSG00000198113 Torsin family 4 member A 9 137277749-137282641 Predicted intracellular proteins Evidence at protein level HPA044913 Enhanced Approved Nucleoplasm Liver cancer:3.44e-4 (unfavourable), Colorectal cancer:6.48e-4 (unfavourable) Expressed in all Mixed stomach: 11.5 Mixed +LPAR1 edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1 ENSG00000198121 Lysophosphatidic acid receptor 1 9 110873263-111038458 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA050667 Approved Nuclear speckles
Plasma membrane Expressed in all Mixed cervix, uterine: 91.5 Cell line enhanced ASC diff: 399.3;ASC TERT1: 236.2;BJ hTERT+: 345.8 +MB PVALB ENSG00000198125 Myoglobin 22 35606764-35637951 Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB000060, HPA003123 Enhanced Group enriched Group enriched 12 heart muscle: 6603.8;skeletal muscle: 12284.0 esophagus: 762.7 Cell line enhanced SiHa: 20.1;SK-BR-3: 131.2;T-47d: 36.7 +OR2L3 ENSG00000198128 Olfactory receptor family 2 subfamily L member 3 1 248060682-248061620 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected thyroid gland: 0.3 Not detected +DEFB107B HsT21816 ENSG00000198129 Defensin beta 107B 8 7495846-7509311 Predicted secreted proteins Evidence at transcript level HPA045626 Approved Not detected Tissue enriched 2828 epididymis: 488.6 endometrium: 0.1 Not detected +HIBCH ENSG00000198130 3-hydroxyisobutyryl-CoA hydrolase 2 190189735-190344193 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036540, HPA036541 Enhanced Approved Nucleoplasm
Mitochondria Renal cancer:1.04e-10 (favourable), Ovarian cancer:1.22e-4 (favourable) Expressed in all Expressed in all kidney: 180.6 Expressed in all +ZNF544 AF020591 ENSG00000198131 Zinc finger protein 544 19 58228594-58277495 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002732 Approved Approved Nucleoplasm Liver cancer:1.04e-5 (unfavourable), Melanoma:3.65e-5 (unfavourable) Expressed in all Expressed in all epididymis: 48.6 Cell line enhanced HEK 293: 153.3 +TMEM229B C14orf83, FLJ33387 ENSG00000198133 Transmembrane protein 229B 14 67447084-67533739 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA046562 Approved Endometrial cancer:1.21e-5 (favourable), Urothelial cancer:1.79e-5 (favourable), Breast cancer:5.38e-4 (favourable) Expressed in all Mixed cervix, uterine: 16.0 Cell line enhanced U-937: 26.9 +SOWAHC ANKRD57, C2orf26, FLJ21870 ENSG00000198142 Sosondowah ankyrin repeat domain family member C 2 109614334-109618990 Predicted intracellular proteins Evidence at protein level HPA056131 Enhanced Approved Cytosol Renal cancer:3.56e-5 (favourable), Endometrial cancer:1.29e-4 (unfavourable), Pancreatic cancer:1.66e-4 (unfavourable) Expressed in all Mixed esophagus: 36.4 Cell line enhanced HDLM-2: 147.6 +ZNF770 FLJ20582, PRO1914 ENSG00000198146 Zinc finger protein 770 15 34978341-34988287 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024518 Approved Expressed in all Expressed in all thyroid gland: 73.6 Expressed in all +NPIPB6 ENSG00000198156 Nuclear pore complex interacting protein family member B6 16 28342555-28363508 Predicted membrane proteins Evidence at protein level HPA011188, HPA053611 Approved Approved Nucleoplasm Not detected Tissue enriched 24 testis: 54.8 skin: 2.3 Mixed +HMGN5 NSBP1 ENSG00000198157 High mobility group nucleosome binding domain 5 X 81113701-81201942 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000511 Approved Supported Nucleus Ovarian cancer:6.60e-4 (favourable) Expressed in all Expressed in all testis: 201.5 Cell line enhanced Karpas-707: 216.2 +MIER1 hMI-ER1, KIAA1610, MI-ER1 ENSG00000198160 MIER1 transcriptional regulator 1 66924895-66988619 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA019589, HPA050306 Enhanced Enhanced Nucleoplasm Glioma:6.18e-8 (favourable), Colorectal cancer:4.96e-4 (favourable) Expressed in all Expressed in all bone marrow: 63.1 Expressed in all +MAN1A2 MAN1B ENSG00000198162 Mannosidase alpha class 1A member 2 1 117367449-117528872 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034559, HPA057364 Enhanced Enhanced Golgi apparatus Ovarian cancer:4.08e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 44.3 Expressed in all +SVIP DKFZp313A2432 ENSG00000198168 Small VCP interacting protein 11 22813799-22830299 Predicted intracellular proteins Evidence at protein level HPA039807 Uncertain Renal cancer:1.77e-8 (favourable) Expressed in all Expressed in all thyroid gland: 39.1 Cell line enhanced SCLC-21H: 58.2 +ZNF251 ENSG00000198169 Zinc finger protein 251 8 144720907-144756417 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA018290 Approved Approved Nucleoplasm Renal cancer:1.42e-9 (unfavourable) Expressed in all Mixed thyroid gland: 13.8 Mixed +DDRGK1 C20orf116, dJ1187M17.3, UFBP1 ENSG00000198171 DDRGK domain containing 1 20 3190350-3204685 Predicted intracellular proteins Evidence at protein level HPA013373, HPA013705 Approved Supported Nucleoli
Endoplasmic reticulum Renal cancer:2.01e-5 (favourable) Expressed in all Expressed in all adrenal gland: 72.4 Expressed in all +FAM47C ENSG00000198173 Family with sequence similarity 47 member C X 37008397-37011666 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 27 testis: 4.8 parathyroid gland: 0.1 Not detected +TFDP1 DILC, Dp-1, DP1, DRTF1 ENSG00000198176 Transcription factor Dp-1 13 113584721-113641470 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB033605, HPA044754, HPA068909 Enhanced Supported Nucleoplasm
Cytosol Liver cancer:1.03e-4 (unfavourable), Stomach cancer:6.17e-4 (favourable), Renal cancer:7.57e-4 (favourable) Expressed in all Expressed in all bone marrow: 99.9 Expressed in all +CLEC4C BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL ENSG00000198178 C-type lectin domain family 4 member C 12 7729415-7751605 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029432 Approved Not detected Tissue enhanced lymph node: 6.0;spleen: 4.6;tonsil: 4.5 appendix,breast: 1.8 Cell line enhanced HDLM-2: 1.9 +ZNF607 FLJ14802, MGC13071 ENSG00000198182 Zinc finger protein 607 19 37696363-37719790 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049465, HPA055018 Uncertain Approved Nucleoplasm Urothelial cancer:5.23e-5 (favourable) Expressed in all Mixed parathyroid gland: 9.6 Mixed +BPIFA1 bA49G10.5, LUNX, PLUNC, SPLUNC1 ENSG00000198183 BPI fold containing family A member 1 20 33235995-33243311 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB025669 Supported Tissue enriched Group enriched 8 cervix, uterine: 9.8;lung: 26.5 urinary bladder: 2.2 Not detected +ZNF334 bA179N14.1 ENSG00000198185 Zinc finger protein 334 20 46499630-46513559 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050022 Uncertain Approved Nucleus
Cytosol Mixed Mixed ovary: 19.4 Cell line enhanced AF22: 15.3;BEWO: 18.7;NTERA-2: 10.4;SCLC-21H: 15.2 +HSD17B11 17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2 ENSG00000198189 Hydroxysteroid 17-beta dehydrogenase 11 4 87336610-87391386 Enzymes, Predicted secreted proteins Evidence at protein level HPA021608 Approved Supported Lipid droplets Expressed in all Expressed in all small intestine: 295.2 Cell line enhanced CAPAN-2: 236.8 +SZT2 C1orf84, FLJ10387, FLJ34502, KIAA0467, RP11-506B15.1, SZT2A, SZT2B ENSG00000198198 Seizure threshold 2 homolog (mouse) 1 43389882-43454247 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029012 Approved Approved Nucleoplasm
Vesicles
Actin filaments Head and neck cancer:1.47e-7 (favourable), Liver cancer:2.53e-4 (unfavourable), Lung cancer:6.20e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.4 Expressed in all +SULT1C2 ST1C1, SULT1C1 ENSG00000198203 Sulfotransferase family 1C member 2 2 108288639-108309915 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007190 Approved Mixed Tissue enhanced kidney: 69.0;stomach: 149.5 duodenum: 28.5 Cell line enhanced RPTEC TERT1: 19.5;RT4: 6.0 +ZXDA ZNF896 ENSG00000198205 Zinc finger, X-linked, duplicated A X 57906708-57910820 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043789 Approved Approved Nucleoplasm Renal cancer:8.55e-4 (favourable) Mixed Mixed ovary: 5.3 Mixed +RPS6KL1 MGC11287 ENSG00000198208 Ribosomal protein S6 kinase like 1 14 74903954-74923396 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA027451, HPA027794 Approved Approved Nucleoplasm Mixed Tissue enhanced cerebral cortex: 31.4 testis: 14.7 Cell line enhanced SCLC-21H: 41.7 +RP11-566K11.2 ENSG00000198211 16 89919165-89936092 Predicted membrane proteins Evidence at protein level CAB011512, HPA043640, HPA046280 Uncertain Not detected Tissue enhanced skin: 1.0 testis: 0.6 Cell line enriched 7 SK-MEL-30: 12.4 +CACNA1E BII, CACH6, CACNL1A6, Cav2.3 ENSG00000198216 Calcium voltage-gated channel subunit alpha1 E 1 181413102-181808084 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA042515, CAB079032 Approved Approved Plasma membrane
Actin filaments
Cytosol Mixed Tissue enriched 8 cerebral cortex: 10.3 adrenal gland: 1.3 Cell line enhanced CACO-2: 1.2;U-266/70: 1.5 +QRICH1 FLJ20259 ENSG00000198218 Glutamine rich 1 3 49029707-49094363 Predicted intracellular proteins Evidence at protein level HPA037677, HPA037678 Approved Enhanced Nucleoplasm Ovarian cancer:7.46e-4 (favourable) Expressed in all Expressed in all testis: 78.9 Expressed in all +CSF2RA CD116, CSF2R ENSG00000198223 Colony stimulating factor 2 receptor alpha subunit X 1268800-1310381 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB016148 Uncertain Cervical cancer:2.38e-5 (favourable), Head and neck cancer:2.81e-4 (favourable), Testis cancer:5.53e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 93.3 appendix: 34.6 Group enriched 8 BEWO: 187.1;HMC-1: 51.2;SK-MEL-30: 109.5 +FKBP1C bA184C23.2 ENSG00000198225 FK506 binding protein 1C 6 63211446-63213024 Predicted intracellular proteins No evidence HPA051798 Uncertain Mixed Not detected appendix: 0.4 Not detected +DDX42 RHELP, RNAHP, SF3b125, SF3B8 ENSG00000198231 DEAD-box helicase 42 17 63773603-63819317 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023447, HPA023571, HPA025941 Enhanced Enhanced Nuclear speckles Liver cancer:2.84e-4 (unfavourable), Renal cancer:9.26e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 75.1 Expressed in all +RPL23A L23A ENSG00000198242 Ribosomal protein L23a 17 28719393-28724359 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA051754 Approved Renal cancer:5.16e-6 (unfavourable) Expressed in all Expressed in all ovary: 2755.0 Expressed in all +SLC29A3 ENT3, FLJ11160 ENSG00000198246 Solute carrier family 29 member 3 10 71319258-71363385 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046085, HPA054976, HPA057905 Approved Supported Golgi apparatus
Vesicles Liver cancer:6.07e-6 (unfavourable), Renal cancer:5.53e-5 (unfavourable), Thyroid cancer:1.16e-4 (favourable) Expressed in all Mixed placenta: 18.8 Cell line enhanced BEWO: 35.2 +STYX ENSG00000198252 Serine/threonine/tyrosine interacting protein 14 52730180-52774998 Predicted intracellular proteins Evidence at protein level HPA040290 Uncertain Approved Nucleoplasm Expressed in all Expressed in all testis: 20.5 Expressed in all +UBL5 ENSG00000198258 Ubiquitin like 5 19 9827892-9830115 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all epididymis: 582.9 Expressed in all +HELZ DHRC, HUMORF5, KIAA0054 ENSG00000198265 Helicase with zinc finger 17 67070438-67245989 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028276 Approved Approved Nucleoli
Plasma membrane
Actin filaments Expressed in all Expressed in all parathyroid gland: 32.9 Expressed in all +TMEM116 FLJ90167 ENSG00000198270 Transmembrane protein 116 12 111931282-112013185 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA040720 Approved Approved Nucleoplasm
Microtubules Renal cancer:1.08e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 57.3 testis: 48.2 Mixed +KRTAP4-5 KAP4.5 ENSG00000198271 Keratin associated protein 4-5 17 41148924-41149802 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +UCKL1 FLJ20517, URKL1 ENSG00000198276 Uridine-cytidine kinase 1 like 1 20 63939829-63956415 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004722, HPA004769 Approved Approved Endoplasmic reticulum Pancreatic cancer:4.42e-4 (favourable) Expressed in all Expressed in all spleen: 40.1 Expressed in all +OR5B21 ENSG00000198283 Olfactory receptor family 5 subfamily B member 21 11 58507175-58508105 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.2 Not detected +CARD11 BIMP3, CARMA1 ENSG00000198286 Caspase recruitment domain family member 11 7 2906141-3043945 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA052984 Approved Renal cancer:6.68e-8 (unfavourable), Urothelial cancer:1.10e-4 (favourable) Expressed in all Tissue enhanced lymph node: 54.4;spleen: 40.2 appendix: 28.3 Cell line enhanced Daudi: 86.5;RT4: 71.8;U-698: 73.9 +ZNF485 ENSG00000198298 Zinc finger protein 485 10 43606407-43617903 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA059356 Uncertain Breast cancer:5.24e-4 (unfavourable) Expressed in all Mixed testis: 7.2 Mixed +PEG3 KIAA0287, ZKSCAN22, ZNF904, ZSCAN24 ENSG00000198300 Paternally expressed 3 19 56810083-56840728 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026070 Approved Supported Nucleoplasm Thyroid cancer:1.56e-4 (unfavourable) Tissue enhanced Tissue enhanced ovary: 340.4;placenta: 197.8 adrenal gland: 102.0 Cell line enhanced BEWO: 100.6;Hep G2: 150.6;RH-30: 70.4 +SDAD1 FLJ10498 ENSG00000198301 SDA1 domain containing 1 4 75940950-75990962 Predicted intracellular proteins Evidence at protein level HPA035949 Uncertain Supported Nucleus
Nucleoli Liver cancer:1.32e-4 (unfavourable), Renal cancer:2.13e-4 (favourable) Expressed in all Expressed in all testis: 38.4 Expressed in all +ZKSCAN8 LD5-1, ZNF192, ZSCAN40 ENSG00000198315 Zinc finger with KRAB and SCAN domains 8 6 28141910-28159472 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003483 Approved Approved Nucleus
Cytosol Endometrial cancer:1.33e-4 (unfavourable) Expressed in all Expressed in all endometrium: 25.0 Expressed in all +FAM109A FLJ32356, IPIP27A, SES1 ENSG00000198324 Family with sequence similarity 109 member A 12 111360651-111369121 Predicted intracellular proteins Evidence at protein level Renal cancer:1.15e-4 (unfavourable) Expressed in all Expressed in all small intestine: 30.8 Mixed +TMEM239 ENSG00000198326 Transmembrane protein 239 20 2816302-2820284 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 270 testis: 38.9 endometrium,placenta: 0.1 Cell line enriched 8 HDLM-2: 7.7 +HYLS1 FLJ32915 ENSG00000198331 HYLS1, centriolar and ciliogenesis associated 11 125883614-125900648 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041210 Uncertain Supported Plasma membrane
Cytosol Liver cancer:1.92e-4 (unfavourable) Expressed in all Tissue enriched 6 testis: 37.5 smooth muscle: 6.6 Mixed +MYL4 ALC1, AMLC, GT1, PRO1957 ENSG00000198336 Myosin light chain 4 17 47200446-47223679 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046859, HPA051884, HPA063034 Enhanced Approved Plasma membrane Group enriched Tissue enriched 21 heart muscle: 1686.3 bone marrow: 79.9 Group enriched 20 HEL: 495.8;K-562: 118.9 +ZNF442 FLJ14356 ENSG00000198342 Zinc finger protein 442 19 12345949-12365905 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA045738, HPA053407 Uncertain Approved Nuclear membrane
Vesicles Mixed Mixed ovary: 6.0 Mixed +ZNF813 FLJ16542 ENSG00000198346 Zinc finger protein 813 19 53467735-53496255 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056406 Uncertain Approved Vesicles Expressed in all Mixed prostate: 8.1 Cell line enhanced RT4: 14.6 +HOXC4 HOX3, HOX3E ENSG00000198353 Homeobox C4 12 54016931-54056030 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053910 Supported Nucleus Mixed Tissue enhanced fallopian tube: 33.9 kidney: 9.4 Cell line enhanced HDLM-2: 29.1;HEK 293: 30.5;SH-SY5Y: 29.6 +DCAF12L2 WDR40C ENSG00000198354 DDB1 and CUL4 associated factor 12 like 2 X 126163499-126166097 Predicted intracellular proteins Evidence at transcript level HPA044737, HPA048981, HPA053138 Approved Mixed Tissue enhanced epididymis: 28.3;testis: 9.8 seminal vesicle: 6.6 Group enriched 7 HAP1: 2.9;NTERA-2: 2.3;U-2 OS: 3.9 +PIM3 ENSG00000198355 Pim-3 proto-oncogene, serine/threonine kinase 22 49960513-49964080 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA068758 Supported Cytosol Renal cancer:8.09e-4 (favourable), Ovarian cancer:9.68e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 61.2 Expressed in all +ASNA1 ARSA-I, GET3, TRC40 ENSG00000198356 ArsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 19 12737139-12748323 Predicted intracellular proteins, Transporters Evidence at protein level HPA045951, HPA048087 Approved Enhanced Nucleus
Nucleoli Renal cancer:4.27e-5 (favourable), Urothelial cancer:8.47e-4 (unfavourable), Cervical cancer:9.53e-4 (favourable) Expressed in all Expressed in all thyroid gland: 93.9 Expressed in all +ASPH BAH, CASQ2BP1, HAAH, JCTN ENSG00000198363 Aspartate beta-hydroxylase 8 61500556-61714640 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA055161, HPA059303 Uncertain Supported Endoplasmic reticulum Renal cancer:1.57e-5 (unfavourable), Cervical cancer:8.07e-5 (unfavourable), Pancreatic cancer:1.75e-4 (unfavourable), Lung cancer:3.61e-4 (unfavourable), Thyroid cancer:4.24e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 403.5 Mixed +SPRED2 FLJ21897, FLJ31917, Spred-2 ENSG00000198369 Sprouty related EVH1 domain containing 2 2 65310851-65432637 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038256, HPA064394 Approved Uncertain Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 44.0 Expressed in all +WWP2 AIP2 ENSG00000198373 WW domain containing E3 ubiquitin protein ligase 2 16 69762306-69941741 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:5.87e-11 (favourable) Expressed in all Expressed in all parathyroid gland: 50.2 Expressed in all +GFPT1 GFA, GFAT, GFAT1, GFPT ENSG00000198380 Glutamine--fructose-6-phosphate transaminase 1 2 69319769-69387254 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047240 Approved Nucleus
Nucleoli Colorectal cancer:7.13e-5 (favourable) Expressed in all Expressed in all thyroid gland: 81.8 Expressed in all +UVRAG VPS38 ENSG00000198382 UV radiation resistance associated 11 75815167-76143195 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA016932 Uncertain Expressed in all Expressed in all parathyroid gland: 42.2 Expressed in all +KRTAP13-1 KAP13.1 ENSG00000198390 Keratin associated protein 13-1 21 30396074-30396822 Predicted intracellular proteins Evidence at protein level Not detected Not detected testis: 0.3 Not detected +ZNF26 FLJ20755, KOX20 ENSG00000198393 Zinc finger protein 26 12 132986365-133032952 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA018329, HPA042406 Uncertain Approved Nuclear bodies
Mitochondria Mixed Mixed epididymis: 6.9 Mixed +TMEM207 ENSG00000198398 Transmembrane protein 207 3 190428655-190449876 Predicted membrane proteins Evidence at protein level HPA014332 Uncertain Not detected Tissue enriched 63 kidney: 18.7 testis: 0.2 Not detected +ITSN2 KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP ENSG00000198399 Intersectin 2 2 24202864-24360714 Predicted intracellular proteins Evidence at protein level HPA036475 Approved Approved Vesicles
Plasma membrane Head and neck cancer:2.98e-4 (favourable) Expressed in all Expressed in all thyroid gland: 84.8 Expressed in all +NTRK1 MTC, TRK, TRKA ENSG00000198400 Neurotrophic receptor tyrosine kinase 1 1 156815640-156881850 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB004606, HPA035799, HPA076570 Approved Uncertain Vesicles
Cytosol Tissue enhanced Tissue enriched 6 adrenal gland: 9.5 testis: 1.6 Cell line enhanced HDLM-2: 10.4;HEL: 11.9;HMC-1: 69.1;SH-SY5Y: 19.1 +MGEA5 MEA5, NCOAT, OGA ENSG00000198408 Meningioma expressed antigen 5 (hyaluronidase) 10 101784443-101818465 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036141, HPA076501 Approved Supported Cytosol Colorectal cancer:8.69e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 129.4 Expressed in all +MT1F MT1 ENSG00000198417 Metallothionein 1F 16 56657694-56660698 Predicted intracellular proteins Evidence at protein level Renal cancer:2.02e-7 (unfavourable) Expressed in all Tissue enhanced kidney: 285.2;thyroid gland: 817.7 small intestine: 138.4 Cell line enhanced HDLM-2: 71.6;NB-4: 79.2;NTERA-2: 77.1;RPTEC TERT1: 250.9 +TCAF1 FAM115A, KIAA0738 ENSG00000198420 TRPM8 channel associated factor 1 7 143851375-143902198 Predicted intracellular proteins Evidence at protein level HPA011732 Approved Ovarian cancer:5.93e-4 (favourable) Expressed in all Expressed in all placenta: 115.9 Mixed +ZNF69 Cos5 ENSG00000198429 Zinc finger protein 69 19 11887784-11914329 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047845 Uncertain Uncertain Nucleus Endometrial cancer:1.55e-4 (favourable) Mixed Tissue enhanced parathyroid gland: 24.9 kidney: 10.3 Cell line enhanced AF22: 13.8 +TXNRD1 GRIM-12, Trxr1, TXNR ENSG00000198431 Thioredoxin reductase 1 12 104215779-104350305 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001395, CAB004607, CAB015834, HPA043871 Approved Supported Nucleus Liver cancer:1.12e-5 (unfavourable), Renal cancer:1.20e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 109.1 Expressed in all +NRARP MGC61598 ENSG00000198435 NOTCH-regulated ankyrin repeat protein 9 137300482-137302251 Predicted intracellular proteins Evidence at transcript level HPA025729 Approved Approved Nucleoplasm
Cytosol Renal cancer:6.73e-6 (unfavourable) Expressed in all Tissue enhanced colon: 38.4 rectum: 22.0 Cell line enhanced HaCaT: 34.8;NTERA-2: 28.5;TIME: 23.6 +ZNF583 FLJ31030 ENSG00000198440 Zinc finger protein 583 19 56397966-56436035 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023805, HPA023957 Uncertain Approved Nucleoli
Cytosol Mixed Mixed testis: 13.7 Mixed +KRTAP4-1 KAP4.1, KAP4.10, KRTAP4-10 ENSG00000198443 Keratin associated protein 4-1 17 41184102-41185342 Predicted intracellular proteins Evidence at transcript level Mixed Not detected colon,small intestine: 0.3 Cell line enhanced A549: 1.5;CAPAN-2: 1.1;HDLM-2: 4.6;SCLC-21H: 1.4 +CCT8L2 CESK1 ENSG00000198445 Chaperonin containing TCP1 subunit 8 like 2 22 16590751-16592810 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 172 testis: 17.1 all non-specific tissues: 0.0 Not detected +ZNF568 DKFZp686B0797 ENSG00000198453 Zinc finger protein 568 19 36916329-36998700 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052061 Uncertain Mixed Mixed parathyroid gland: 14.3 Mixed +ZXDB ZNF905 ENSG00000198455 Zinc finger, X-linked, duplicated B X 57591652-57597545 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA043789 Approved Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 10.0 Mixed +ZNF480 MGC32104 ENSG00000198464 Zinc finger protein 480 19 52297177-52325922 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042218 Uncertain Supported Nucleoplasm Melanoma:1.65e-4 (unfavourable), Renal cancer:2.03e-4 (favourable) Expressed in all Mixed lymph node: 14.8 Mixed +ZNF587 FLJ14710, FLJ20813, UBF-fl, ZF6 ENSG00000198466 Zinc finger protein 587 19 57849857-57865112 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042125, HPA043288, HPA056213 Uncertain Uncertain Nucleoplasm Renal cancer:7.98e-4 (unfavourable) Expressed in all Mixed rectum: 17.0 Expressed in all +TPM2 AMCD1, DA1, NEM4 ENSG00000198467 Tropomyosin 2 (beta) 9 35681992-35691020 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047089, HPA053624 Approved Renal cancer:8.51e-10 (unfavourable), Colorectal cancer:2.64e-4 (unfavourable) Expressed in all Tissue enriched 6 skeletal muscle: 13466.0 smooth muscle: 2282.0 Cell line enhanced BJ: 1627.6 +RTP2 MGC78665, Z3CXXC2 ENSG00000198471 Receptor transporter protein 2 3 187698259-187702557 Predicted membrane proteins Evidence at protein level HPA026875 Uncertain Not detected Not detected testis: 0.9 Cell line enriched 12 SK-BR-3: 1.3 +SH3BGRL2 ENSG00000198478 SH3 domain binding glutamate rich protein like 2 6 79631283-79703659 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047486 Approved Supported Nucleoplasm Renal cancer:2.24e-4 (favourable) Expressed in all Expressed in all thyroid gland: 98.4 Cell line enhanced CACO-2: 66.4;HEL: 37.0 +ZNF808 ENSG00000198482 Zinc finger protein 808 19 52527652-52564464 Predicted intracellular proteins, Transcription factors Evidence at protein level Urothelial cancer:3.88e-4 (favourable), Thyroid cancer:7.82e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 8.8 Mixed +ANKRD35 FLJ25124 ENSG00000198483 Ankyrin repeat domain 35 1 145866560-145885866 Predicted intracellular proteins Evidence at protein level HPA035453 Enhanced Cervical cancer:2.90e-4 (favourable), Breast cancer:9.35e-4 (favourable) Mixed Group enriched 6 cervix, uterine: 30.8;esophagus: 16.6;skin: 69.8 tonsil: 6.1 Cell line enhanced ASC TERT1: 6.6;THP-1: 4.5;TIME: 6.9;U-87 MG: 8.1;U-937: 5.9 +B3GNT6 B3Gn-T6 ENSG00000198488 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 11 77034398-77041973 Enzymes, Predicted secreted proteins Evidence at protein level HPA012158, HPA039805 Enhanced Approved Colorectal cancer:2.31e-4 (favourable) Group enriched Tissue enhanced colon: 21.7;rectum: 18.2;stomach: 23.5 small intestine: 7.9 Not detected +YTHDF2 CAHL, HGRG8, NY-REN-2 ENSG00000198492 YTH N6-methyladenosine RNA binding protein 2 1 28736621-28769775 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030063, HPA054080, HPA059621 Approved Enhanced Cytosol
Cytoplasmic bodies Liver cancer:6.14e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 58.9 Expressed in all +TMA16 C4orf43, FLJ11184 ENSG00000198498 Translation machinery associated 16 homolog 4 163494442-163520539 Predicted intracellular proteins Evidence at protein level HPA041571, HPA052688 Uncertain Enhanced Nucleoli Liver cancer:2.70e-5 (unfavourable), Lung cancer:4.40e-4 (unfavourable), Renal cancer:7.70e-4 (unfavourable) Expressed in all Expressed in all testis: 43.7 Expressed in all +HLA-DRB5 ENSG00000198502 Major histocompatibility complex, class II, DR beta 5 6 32517343-32530287 Predicted membrane proteins Evidence at protein level HPA043151 Supported Endometrial cancer:7.89e-4 (favourable) Expressed in all Tissue enhanced lung: 530.8 lymph node: 397.6 Group enriched 7 HDLM-2: 589.3;HMC-1: 134.7;U-698: 129.3;U-87 MG: 232.1 +ATL1 AD-FSP, FSP1, SPG3, SPG3A ENSG00000198513 Atlastin GTPase 1 14 50532509-50633068 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027550 Enhanced Mixed Tissue enhanced cerebral cortex: 96.9 smooth muscle: 22.0 Cell line enhanced HDLM-2: 18.1;SCLC-21H: 20.2;SiHa: 19.9 +CNGA1 CNCG, CNCG1, CNG1, RCNC1, RCNCa, RP49 ENSG00000198515 Cyclic nucleotide gated channel alpha 1 4 47935977-48016672 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Mixed Mixed liver: 14.2 Cell line enhanced CAPAN-2: 9.1;RT4: 6.7;U-2 OS: 3.3 +MAFK NFE2U, P18 ENSG00000198517 MAF bZIP transcription factor K 7 1530714-1543043 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026820, HPA060841 Approved Enhanced Nucleoplasm Expressed in all Expressed in all placenta: 36.8 Expressed in all +C1orf228 MGC33556, NCRNA00082, p40 ENSG00000198520 Chromosome 1 open reading frame 228 1 44674692-44725591 Predicted intracellular proteins Evidence at protein level HPA034769 Uncertain Uncertain Cytosol Endometrial cancer:8.64e-4 (favourable) Mixed Tissue enhanced fallopian tube: 13.5;testis: 21.4 epididymis: 4.7 Cell line enhanced HL-60: 6.3;MOLT-4: 5.3;NB-4: 5.8;U-937: 9.7 +ZNF43 HTF6, KOX27, ZNF39L1 ENSG00000198521 Zinc finger protein 43 19 21804949-21852125 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA050271 Uncertain Ovarian cancer:3.16e-5 (favourable) Mixed Mixed testis: 16.2 Cell line enhanced MOLT-4: 31.1 +GPN1 ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1 ENSG00000198522 GPN-loop GTPase 1 2 27628247-27651508 Predicted intracellular proteins Evidence at protein level HPA036793, HPA036794, CAB037303 Uncertain Supported Nucleoplasm
Mitochondria
Cytosol Liver cancer:1.71e-5 (unfavourable), Endometrial cancer:2.88e-5 (unfavourable) Expressed in all Expressed in all testis: 47.1 Expressed in all +PLN CMD1P, PLB ENSG00000198523 Phospholamban 6 118548298-118560730 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB005597, HPA026900 Enhanced Renal cancer:4.11e-4 (unfavourable), Urothelial cancer:5.59e-4 (unfavourable) Mixed Tissue enriched 5 heart muscle: 1461.9 smooth muscle: 270.2 Not detected +C2CD4A FAM148A, NLF1 ENSG00000198535 C2 calcium dependent domain containing 4A 15 62066977-62070917 Predicted intracellular proteins Evidence at transcript level Renal cancer:4.15e-4 (unfavourable) Mixed Mixed endometrium: 2.3 Cell line enriched 14 RPTEC TERT1: 22.6 +ZNF28 DKFZp781D0275, KOX24 ENSG00000198538 Zinc finger protein 28 19 52797409-52857600 Predicted intracellular proteins, Transcription factors Evidence at transcript level Breast cancer:9.29e-4 (unfavourable) Expressed in all Mixed thyroid gland: 17.9 Mixed +ITGBL1 OSCP, TIED ENSG00000198542 Integrin subunit beta like 1 13 101452593-101720856 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005676 Uncertain Urothelial cancer:2.70e-4 (unfavourable) Mixed Tissue enhanced gallbladder: 59.8 placenta: 47.2 Cell line enhanced ASC diff: 142.9;fHDF/TERT166: 267.4;LHCN-M2: 259.5 +ZNF511 MGC30006 ENSG00000198546 Zinc finger protein 511 10 133308475-133313162 Predicted membrane proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA035360 Uncertain Renal cancer:1.13e-4 (unfavourable) Expressed in all Expressed in all ovary: 12.2 Expressed in all +ZNF627 FLJ90365 ENSG00000198551 Zinc finger protein 627 19 11559374-11619135 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049770, HPA073463 Uncertain Approved Nucleus
Nucleoli Renal cancer:6.93e-7 (favourable), Head and neck cancer:8.12e-4 (favourable) Expressed in all Expressed in all thyroid gland: 20.7 Expressed in all +KCNRG ENSG00000198553 Potassium channel regulator 13 50015254-50020922 Predicted intracellular proteins Evidence at protein level HPA001027 Uncertain Vesicles Endometrial cancer:2.61e-5 (favourable) Mixed Tissue enriched 12 fallopian tube: 52.2 lung: 4.5 Mixed +WDHD1 AND-1, CHTF4, CTF4 ENSG00000198554 WD repeat and HMG-box DNA binding protein 1 14 54938950-55027105 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001122 Enhanced Enhanced Nucleoplasm Pancreatic cancer:9.24e-4 (unfavourable) Expressed in all Mixed testis: 9.8 Expressed in all +ZNF789 ENSG00000198556 Zinc finger protein 789 7 99472841-99503650 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029500, HPA050793 Uncertain Enhanced Nucleoplasm Urothelial cancer:5.31e-6 (favourable), Renal cancer:3.56e-4 (unfavourable), Pancreatic cancer:7.14e-4 (favourable) Expressed in all Mixed prostate: 13.9 Expressed in all +CTNND1 CTNND, KIAA0384, p120, p120cas, p120ctn ENSG00000198561 Catenin delta 1 11 57753243-57819546 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003837, HPA015954, HPA015955 Enhanced Enhanced Plasma membrane Pancreatic cancer:3.02e-4 (unfavourable), Renal cancer:3.54e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 196.2 Expressed in all +DDX39B BAT1, D6S81E, UAP56 ENSG00000198563 DExD-box helicase 39B 6 31530219-31542448 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB034012, HPA055334, HPA058450 Enhanced Enhanced Nuclear speckles Renal cancer:1.11e-6 (unfavourable), Urothelial cancer:1.43e-5 (favourable) Expressed in all Expressed in all epididymis: 45.0 Expressed in all +SLC34A3 FLJ38680, NPTIIc ENSG00000198569 Solute carrier family 34 member 3 9 137230757-137236554 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA023776 Enhanced Mixed Group enriched 15 kidney: 11.8;small intestine: 9.1 testis: 0.7 Cell line enhanced CAPAN-2: 2.9;MCF7: 4.2 +RD3 C1orf36, LCA12 ENSG00000198570 Retinal degeneration 3 1 211476522-211492917 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029941, HPA029943 Supported Tissue enhanced Not detected adrenal gland,epididymis: 0.3 Group enriched 14 HEL: 2.4;HMC-1: 6.0;SH-SY5Y: 10.6 +SPANXC CT11.3, CTp11 ENSG00000198573 SPANX family member C X 141241463-141242496 Predicted intracellular proteins Evidence at protein level HPA046423, HPA073647 Supported Supported Nucleoplasm
Vesicles Tissue enhanced Tissue enriched 187 testis: 18.7 all non-specific tissues: 0.0 Cell line enhanced A-431: 7.8;U-2 OS: 4.3 +SH2D1B EAT2 ENSG00000198574 SH2 domain containing 1B 1 162395266-162412138 Predicted intracellular proteins Evidence at protein level HPA054791 Uncertain Not detected Tissue enhanced spleen: 10.3 lung: 3.3 Cell line enhanced CAPAN-2: 1.3;EFO-21: 2.5;Karpas-707: 3.2;TIME: 1.1 +ARC Arg3.1, KIAA0278 ENSG00000198576 Activity regulated cytoskeleton associated protein 8 142611044-142614472 Predicted intracellular proteins Evidence at protein level HPA056430, CAB079013 Supported Approved Vesicles
Microtubules Tissue enriched Group enriched 7 adipose tissue: 14.2;adrenal gland: 13.4;cerebral cortex: 14.4;gallbladder: 3.3;seminal vesicle: 5.5 placenta: 1.4 Cell line enhanced HEK 293: 9.2;SCLC-21H: 27.7;U-2 OS: 11.9;U-87 MG: 12.5 +NUDT16 FLJ31265 ENSG00000198585 Nudix hydrolase 16 3 131381671-131388830 Enzymes, Predicted intracellular proteins Evidence at protein level HPA060452, HPA062492 Uncertain Supported Nucleus
Nucleoli Renal cancer:1.05e-7 (favourable), Cervical cancer:9.39e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 54.8 Mixed +TLK1 KIAA0137, PKU-BETA ENSG00000198586 Tousled like kinase 1 2 170990823-171231314 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016043 Approved Enhanced Nucleus Expressed in all Expressed in all parathyroid gland: 40.9 Expressed in all +LRBA BGL, CDC4L, LAB300, LBA ENSG00000198589 LPS responsive beige-like anchor protein 4 150264531-151015727 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019366, HPA023597 Approved Approved Golgi apparatus
Cytosol Renal cancer:2.22e-16 (favourable) Expressed in all Expressed in all parathyroid gland: 62.7 Expressed in all +C3orf35 APRG1 ENSG00000198590 Chromosome 3 open reading frame 35 3 37386269-37435497 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Not detected Mixed testis: 4.4 Mixed +ZNF536 KIAA0390 ENSG00000198597 Zinc finger protein 536 19 30228290-30713538 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA077341 Approved Nucleus
Cell Junctions Mixed Tissue enhanced cerebral cortex: 19.0 thyroid gland: 5.3 Cell line enhanced HAP1: 11.4;SH-SY5Y: 31.3;WM-115: 12.5 +MMP17 MT4-MMP ENSG00000198598 Matrix metallopeptidase 17 12 131828393-131851783 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enhanced cerebral cortex: 24.0 skin: 8.2 Group enriched 5 REH: 53.0;SK-MEL-30: 109.1;WM-115: 201.0 +OR2M2 OR2M2Q, OST423 ENSG00000198601 Olfactory receptor family 2 subfamily M member 2 1 248179986-248181029 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +BAZ1A ACF1, hACF1, WALp1, WCRF180 ENSG00000198604 Bromodomain adjacent to zinc finger domain 1A 14 34752731-34875647 Predicted intracellular proteins Evidence at protein level HPA002730 Supported Uncertain Endoplasmic reticulum Renal cancer:1.31e-7 (unfavourable), Liver cancer:4.44e-4 (unfavourable) Expressed in all Expressed in all testis: 55.7 Expressed in all +AKR1C4 3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581 ENSG00000198610 Aldo-keto reductase family 1 member C4 10 5195462-5218949 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA044720, HPA068265 Uncertain Approved Nucleus
Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Tissue enriched Tissue enriched 6 liver: 360.3 gallbladder: 64.2 Cell line enriched 8 HDLM-2: 6.1 +COPS8 COP9, CSN8, MGC1297, SGN8 ENSG00000198612 COP9 signalosome subunit 8 2 237085312-237100466 Predicted intracellular proteins Evidence at protein level HPA036485 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:4.70e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 116.1 Expressed in all +CCDC69 DKFZP434C171, FLJ13705 ENSG00000198624 Coiled-coil domain containing 69 5 151181052-151224145 Predicted intracellular proteins Evidence at protein level HPA043648, HPA052896 Uncertain Approved Golgi apparatus
Plasma membrane
Actin filaments Breast cancer:3.21e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 112.8 Cell line enhanced ASC diff: 80.3;Daudi: 136.8;U-266/70: 89.8;U-698: 84.7 +MDM4 HDMX, MDMX ENSG00000198625 MDM4, p53 regulator 1 204516379-204558120 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA018919, HPA048821 Approved Supported Nucleus Renal cancer:7.06e-6 (unfavourable), Urothelial cancer:2.49e-4 (favourable), Prostate cancer:9.87e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 37.5 Expressed in all +RYR2 ARVC2, ARVD2, VTSIP ENSG00000198626 Ryanodine receptor 2 1 237042205-237833988 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA020028 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Mixed Tissue enriched 8 heart muscle: 65.9 cerebral cortex: 7.9 Cell line enhanced HDLM-2: 4.8;HEK 293: 6.3;K-562: 2.0;NTERA-2: 2.5;U-937: 2.5 +ZNF534 FLJ25344, KRBO3 ENSG00000198633 Zinc finger protein 534 19 52429187-52452315 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enriched Tissue enhanced testis: 2.4 cerebral cortex: 0.9 Not detected +KLHL9 FLJ13568, KIAA1354 ENSG00000198642 Kelch like family member 9 9 21329671-21335380 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046039, HPA059901 Approved Approved Cytosol Renal cancer:9.43e-10 (favourable) Expressed in all Expressed in all thyroid gland: 27.0 Mixed +FAM3D EF7, OIT1 ENSG00000198643 Family with sequence similarity 3 member D 3 58633946-58666848 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013844 Approved Head and neck cancer:1.89e-4 (favourable), Breast cancer:7.51e-4 (favourable) Tissue enhanced Tissue enhanced colon: 318.5;rectum: 484.7 salivary gland: 191.6 Not detected +NCOA6 AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP ENSG00000198646 Nuclear receptor coactivator 6 20 34689097-34825649 Predicted intracellular proteins Evidence at protein level HPA004198, HPA050211 Supported Supported Nucleoplasm Renal cancer:8.78e-5 (favourable), Liver cancer:4.65e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.6 Expressed in all +STK39 DCHT, SPAK ENSG00000198648 Serine/threonine kinase 39 2 167954020-168248141 Enzymes, Predicted intracellular proteins Evidence at protein level CAB046022, HPA061803, HPA062802 Enhanced Supported Nucleoplasm
Vesicles
Cytosol Liver cancer:5.67e-5 (unfavourable), Breast cancer:3.96e-4 (favourable) Expressed in all Mixed testis: 71.4 Mixed +TAT ENSG00000198650 Tyrosine aminotransferase 16 71565660-71577130 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Liver cancer:6.51e-4 (favourable) Tissue enriched Tissue enriched 8 liver: 619.8 breast: 75.9 Cell line enhanced Hep G2: 1.7 +C6orf89 BRAP, FLJ25357 ENSG00000198663 Chromosome 6 open reading frame 89 6 36871870-36928964 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012548 Uncertain Renal cancer:5.77e-5 (favourable) Expressed in all Expressed in all thyroid gland: 97.2 Expressed in all +CALM1 CALML2, CAMI, DD132, PHKD ENSG00000198668 Calmodulin 1 14 90396502-90408261 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level CAB018558, HPA044999 Supported Approved Vesicles Urothelial cancer:2.38e-5 (unfavourable), Pancreatic cancer:5.62e-4 (favourable), Renal cancer:6.49e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1325.6 Expressed in all +LPA LP, Lp(a) ENSG00000198670 Lipoprotein(a) 6 160531483-160664259 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016072, HPA060604 Supported Tissue enriched Tissue enriched 25 liver: 41.5 seminal vesicle: 1.6 Not detected +FAM19A2 TAFA-2, TAFA2 ENSG00000198673 Family with sequence similarity 19 member A2, C-C motif chemokine like 12 61708259-62279150 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced cerebral cortex: 26.3 seminal vesicle: 10.0 Cell line enhanced hTCEpi: 4.1;SCLC-21H: 2.5;WM-115: 4.7 +OR10G6 OR10G6P, OR10G6Q ENSG00000198674 Olfactory receptor family 10 subfamily G member 6 11 123994163-123995161 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +TTC37 KIAA0372, THES ENSG00000198677 Tetratricopeptide repeat domain 37 5 95463895-95555007 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037905 Approved Supported Nucleoplasm
Cytosol Colorectal cancer:2.62e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 82.3 Expressed in all +TUSC1 TSG-9 ENSG00000198680 Tumor suppressor candidate 1 9 25676389-25678440 Predicted intracellular proteins Evidence at protein level HPA051426 Approved Approved Nucleus
Vesicles Expressed in all Expressed in all testis: 16.5 Cell line enhanced HEL: 34.6 +MAGEA1 CT1.1, MAGE1, MGC9326 ENSG00000198681 MAGE family member A1 X 153179285-153183880 Predicted intracellular proteins Evidence at protein level CAB002620 Enhanced Supported Cytosol Mixed Tissue enriched 73 testis: 7.3 all non-specific tissues: 0.0 Group enriched 13 HEL: 66.7;HMC-1: 109.1;RPMI-8226: 44.6;U-2 OS: 123.1;U-266/70: 135.4;U-266/84: 212.3 +PAPSS2 ATPSK2 ENSG00000198682 3'-phosphoadenosine 5'-phosphosulfate synthase 2 10 87659613-87747705 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA071224 Approved Mitochondria Melanoma:1.33e-6 (unfavourable), Thyroid cancer:3.21e-5 (unfavourable), Pancreatic cancer:6.58e-4 (favourable) Expressed in all Expressed in all adrenal gland: 157.6 Cell line enhanced fHDF/TERT166: 365.8 +SLC9A6 KIAA0267, NHE6 ENSG00000198689 Solute carrier family 9 member A6 X 135973841-136047269 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA059445, HPA059590 Enhanced Supported Vesicles Expressed in all Tissue enhanced cerebral cortex: 67.9 parathyroid gland: 16.6 Mixed +FAN1 KIAA1018, MTMR15 ENSG00000198690 FANCD2 and FANCI associated nuclease 1 15 30903852-30943108 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048198 Supported Nucleoplasm
Cytokinetic bridge
Cytosol Renal cancer:1.42e-6 (favourable) Expressed in all Expressed in all epididymis: 11.4 Expressed in all +ABCA4 ABCR, ARMD2, CORD3, FFM, RP19, STGD, STGD1 ENSG00000198691 ATP binding cassette subfamily A member 4 1 93992835-94121132 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Lung cancer:2.45e-4 (favourable), Urothelial cancer:2.72e-4 (unfavourable) Tissue enhanced Tissue enhanced epididymis: 9.9 kidney: 4.2 Cell line enhanced BEWO: 2.8;EFO-21: 6.2;SK-BR-3: 1.9 +EIF1AY ENSG00000198692 Eukaryotic translation initiation factor 1A, Y-linked Y 20575725-20593154 Predicted intracellular proteins Evidence at protein level HPA002561 Uncertain Approved Approved Cytosol Mixed Mixed prostate: 42.2 Cell line enhanced HEL: 197.1;U-698: 240.9 +MT-ND6 MTND6, NAD6, ND6 ENSG00000198695 Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 MT 14149-14673 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Renal cancer:8.91e-6 (favourable) Expressed in all Expressed in all heart muscle: 22714.1 Expressed in all +IPO9 FLJ10402, Imp9 ENSG00000198700 Importin 9 1 201829141-201884294 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA059540 Approved Vesicles
Cytosol Liver cancer:4.11e-5 (unfavourable), Renal cancer:2.86e-4 (unfavourable), Urothelial cancer:5.78e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.3 Expressed in all +GPX6 GPXP3 ENSG00000198704 Glutathione peroxidase 6 6 28503296-28528215 Enzymes, Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 12 epididymis: 4.0 testis: 0.3 Not detected +CEP290 3H11Ag, BBS14, CT87, FLJ13615, JBTS5, KIAA0373, LCA10, MKS4, NPHP6, POC3, rd16, SLSN6 ENSG00000198707 Centrosomal protein 290 12 88049014-88142216 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB029995, HPA043918, HPA064397 Approved Supported Centrosome Renal cancer:3.21e-6 (unfavourable) Expressed in all Mixed parathyroid gland: 21.9 Expressed in all +MT-CO2 CO2, COX2, MTCO2 ENSG00000198712 Mitochondrially encoded cytochrome c oxidase II MT 7586-8269 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB016243, HPA051505, HPA054758 Enhanced Liver cancer:2.89e-4 (favourable), Pancreatic cancer:7.10e-4 (favourable) Expressed in all Expressed in all heart muscle: 40900.1 Expressed in all +GLMP C1orf85, MGC31963, NCU-G1 ENSG00000198715 Glycosylated lysosomal membrane protein 1 156290089-156295689 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA029121 Uncertain Liver cancer:6.35e-5 (unfavourable) Expressed in all Expressed in all prostate: 96.6 Mixed +TOGARAM1 crescerin, Crescerin-1, FAM179B, KIAA0423 ENSG00000198718 TOG array regulator of axonemal microtubules 1 14 44962208-45074431 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA050849, HPA053559 Uncertain Approved Nucleoplasm Renal cancer:8.38e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 16.7 Mixed +DLL1 ENSG00000198719 Delta like canonical Notch ligand 1 6 170282206-170306565 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA078298 Uncertain Nucleoplasm Expressed in all Mixed spleen: 20.0 Cell line enhanced HaCaT: 7.0;HBEC3-KT: 8.8;NB-4: 13.1;THP-1: 11.4 +ANKRD13B FLJ25555 ENSG00000198720 Ankyrin repeat domain 13B 17 29589769-29614761 Predicted intracellular proteins Evidence at protein level HPA051886, HPA063748 Uncertain Supported Vesicles Renal cancer:5.92e-6 (unfavourable), Pancreatic cancer:7.58e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 25.9 testis: 17.6 Cell line enhanced SCLC-21H: 75.3;SH-SY5Y: 76.2 +ECI2 ACBD2, DRS1, HCA88, PECI ENSG00000198721 Enoyl-CoA delta isomerase 2 6 4115689-4135597 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022130, HPA031626 Enhanced Enhanced Peroxisomes Renal cancer:2.04e-6 (favourable), Head and neck cancer:2.85e-4 (unfavourable) Expressed in all Expressed in all kidney: 238.6 Expressed in all +UNC13B hmunc13, UNC13, Unc13h2 ENSG00000198722 Unc-13 homolog B 9 35161992-35405338 Predicted intracellular proteins Evidence at protein level HPA024493, HPA062300 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:4.34e-11 (favourable), Lung cancer:6.59e-5 (favourable), Head and neck cancer:8.51e-5 (favourable), Pancreatic cancer:3.71e-4 (favourable), Colorectal cancer:4.96e-4 (favourable) Expressed in all Mixed lung: 58.2 Mixed +C19orf45 FLJ35784 ENSG00000198723 Chromosome 19 open reading frame 45 19 7492976-7508450 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 7 testis: 16.7 skin: 2.2 Not detected +MT-CYB COB, CYTB, MTCYB, UQCR3 ENSG00000198727 Mitochondrially encoded cytochrome b MT 14747-15887 Disease related genes, Predicted membrane proteins Evidence at protein level CAB032215, HPA068400 Enhanced Approved Mitochondria Liver cancer:5.96e-4 (favourable) Expressed in all Expressed in all heart muscle: 23224.8 Expressed in all +LDB1 CLIM2, NLI ENSG00000198728 LIM domain binding 1 10 102107560-102120453 Predicted intracellular proteins Evidence at protein level HPA034488 Approved Approved Nucleoplasm Expressed in all Expressed in all skin: 158.2 Expressed in all +PPP1R14C CPI17-like, KEPI, NY-BR-81 ENSG00000198729 Protein phosphatase 1 regulatory inhibitor subunit 14C 6 150143076-150250357 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced skin: 76.2;thyroid gland: 101.5 heart muscle: 52.5 Cell line enhanced HBEC3-KT: 63.9;hTCEpi: 77.1 +CTR9 KIAA0155, p150TSP, SH2BP1, TSBP ENSG00000198730 CTR9 homolog, Paf1/RNA polymerase II complex component 11 10750987-10779743 Predicted intracellular proteins Evidence at protein level HPA061027, HPA068122 Enhanced Enhanced Nucleoplasm Renal cancer:3.65e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 59.9 Expressed in all +SMOC1 ENSG00000198732 SPARC related modular calcium binding 1 14 69854131-70032366 Disease related genes, Predicted secreted proteins Evidence at protein level HPA004153, CAB034427 Approved Approved Plasma membrane Mixed Tissue enhanced cerebral cortex: 135.8 prostate: 66.2 Cell line enhanced AF22: 61.2;HeLa: 115.9;SiHa: 108.4;U-266/70: 48.2;U-87 MG: 61.4 +F5 ENSG00000198734 Coagulation factor V 1 169514166-169586588 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002036 Uncertain Approved Golgi apparatus Stomach cancer:3.39e-4 (unfavourable) Tissue enriched Group enriched 11 gallbladder: 28.4;liver: 93.7;placenta: 68.2 fallopian tube: 5.9 Cell line enriched 7 Hep G2: 22.8 +MSRB1 SelR, SelX, SepR, SEPX1 ENSG00000198736 Methionine sulfoxide reductase B1 16 1938210-1943326 Predicted intracellular proteins Evidence at protein level CAB008650, HPA043463, HPA069557 Approved Enhanced Nucleoplasm Expressed in all Expressed in all liver: 61.7 Expressed in all +LRRTM3 ENSG00000198739 Leucine rich repeat transmembrane neuronal 3 10 66926006-67099830 Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 5 cerebral cortex: 22.6 ovary: 4.2 Cell line enhanced AF22: 1.9;HAP1: 5.7;NTERA-2: 1.2 +ZNF652 KIAA0924 ENSG00000198740 Zinc finger protein 652 17 49289206-49362473 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044408 Uncertain Approved Nucleus Endometrial cancer:1.35e-4 (favourable) Expressed in all Mixed breast: 7.2 Mixed +SMURF1 KIAA1625 ENSG00000198742 SMAD specific E3 ubiquitin protein ligase 1 7 99027438-99144100 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055245 Approved Expressed in all Expressed in all testis: 22.9 Expressed in all +SLC5A3 SMIT, SMIT1 ENSG00000198743 Solute carrier family 5 member 3 21 34073570-34106262 Predicted membrane proteins, Transporters Evidence at protein level HPA029791 Approved Plasma membrane
Cytosol Pancreatic cancer:1.98e-5 (unfavourable), Renal cancer:4.72e-4 (unfavourable) Expressed in all Tissue enhanced thyroid gland: 42.2 kidney: 33.1 Expressed in all +GPATCH3 FLJ12455, GPATC3 ENSG00000198746 G-patch domain containing 3 1 26890488-26900466 Predicted intracellular proteins Evidence at protein level HPA032078, HPA054973 Approved Approved Nucleoplasm
Cytosol Liver cancer:1.23e-7 (unfavourable), Pancreatic cancer:6.42e-4 (favourable) Expressed in all Expressed in all bone marrow: 15.3 Expressed in all +CDC42BPB KIAA1124, MRCKB ENSG00000198752 CDC42 binding protein kinase beta 14 102932379-103057462 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022821 Approved Renal cancer:8.67e-10 (favourable), Lung cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 75.1 Mixed +PLXNB3 PLEXB3, PLEXR, PLXN6 ENSG00000198753 Plexin B3 X 153764196-153779346 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048046 Enhanced Breast cancer:6.13e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 67.3 adrenal gland: 19.7 Cell line enhanced WM-115: 69.8 +OXCT2 FKSG25, FLJ00030, SCOT-T ENSG00000198754 3-oxoacid CoA-transferase 2 1 39769523-39771348 Enzymes, Predicted secreted proteins Evidence at protein level HPA075423 Enhanced Not detected Tissue enriched 12 testis: 37.4 thyroid gland: 3.0 Cell line enhanced Karpas-707: 5.4;THP-1: 5.6 +RPL10A Csa-19, L10A, NEDD6 ENSG00000198755 Ribosomal protein L10a 6 35468408-35470785 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA053803 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:3.77e-4 (unfavourable) Expressed in all Expressed in all ovary: 3924.2 Expressed in all +COLGALT2 C1orf17, GLT25D2, KIAA0584 ENSG00000198756 Collagen beta(1-O)galactosyltransferase 2 1 183929854-184037729 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031749, HPA031750 Approved Approved Nucleus
Vesicles Tissue enhanced Tissue enriched 5 cerebral cortex: 46.4 prostate: 8.8 Cell line enhanced Hep G2: 11.7;SK-MEL-30: 14.3;U-251 MG: 14.6;WM-115: 22.1 +EPS8L3 FLJ21522, MGC16817 ENSG00000198758 EPS8 like 3 1 109750080-109764027 Predicted intracellular proteins Evidence at protein level HPA030998 Approved Approved Vesicles Renal cancer:2.52e-5 (unfavourable), Liver cancer:4.13e-5 (unfavourable), Urothelial cancer:1.82e-4 (favourable) Group enriched Group enriched 7 colon: 75.0;duodenum: 152.1;gallbladder: 59.8;rectum: 86.1;small intestine: 167.1;stomach: 53.4 appendix: 15.1 Group enriched 12 CACO-2: 13.3;CAPAN-2: 13.3;EFO-21: 5.8;Hep G2: 25.0 +EGFL6 MAEG ENSG00000198759 EGF like domain multiple 6 X 13569605-13633575 Predicted secreted proteins Evidence at protein level HPA001838 Enhanced Ovarian cancer:4.95e-4 (favourable), Head and neck cancer:9.73e-4 (favourable) Mixed Tissue enriched 34 placenta: 921.8 lung: 26.8 Group enriched 5 BJ hTERT+: 3.5;NTERA-2: 1.7 +MT-ND2 MTND2, NAD2, ND2 ENSG00000198763 Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 MT 4470-5511 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all heart muscle: 24880.0 Expressed in all +SYCP1 CT8, HOM-TES-14, SCP1 ENSG00000198765 Synaptonemal complex protein 1 1 114854803-114995370 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021083 Enhanced Not detected Tissue enriched 96 testis: 72.5 breast: 0.7 Cell line enriched 65 THP-1: 11.4 +APCDD1L FLJ90166 ENSG00000198768 APC down-regulated 1 like 20 58459101-58515131 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067015 Uncertain Uncertain Mitochondria Mixed Tissue enhanced breast: 6.5;salivary gland: 11.6 kidney: 2.9 Cell line enhanced fHDF/TERT166: 88.4;hTEC/SVTERT24-B: 39.4;HUVEC TERT2: 33.7;TIME: 65.0;U-87 MG: 47.5 +RCSD1 CapZIP, MGC21854, MK2S4 ENSG00000198771 RCSD domain containing 1 1 167630093-167706249 Predicted intracellular proteins Evidence at protein level HPA016597 Enhanced Uncertain Nucleoplasm
Plasma membrane Head and neck cancer:2.97e-4 (favourable) Expressed in all Tissue enhanced lymph node: 107.2 spleen: 72.4 Cell line enhanced Daudi: 144.4;REH: 185.8;RPMI-8226: 96.4;U-266/70: 99.4;U-698: 91.2 +RASSF9 P-CIP1, PAMCI ENSG00000198774 Ras association domain family member 9 12 85800697-85836570 Predicted intracellular proteins Evidence at transcript level HPA039428, HPA039678 Approved Mixed Mixed fallopian tube: 10.1 Cell line enhanced HeLa: 2.6;HUVEC TERT2: 2.0;RPTEC TERT1: 2.8;U-138 MG: 2.7 +FAM169A KIAA0888, SLAP75 ENSG00000198780 Family with sequence similarity 169 member A 5 74777574-74866951 Predicted intracellular proteins Evidence at protein level HPA041574 Enhanced Supported Nuclear membrane
Cytosol Mixed Tissue enhanced cerebral cortex: 29.2;testis: 25.4 epididymis: 23.2 Cell line enhanced BEWO: 35.3 +ZNF830 CCDC16, MGC20398, OMCG1 ENSG00000198783 Zinc finger protein 830 17 34961530-34963775 Predicted intracellular proteins Evidence at protein level HPA024754, HPA027211 Enhanced Enhanced Nucleoplasm Prostate cancer:2.01e-4 (unfavourable) Expressed in all Expressed in all spleen: 16.6 Expressed in all +GRIN3A GluN3A ENSG00000198785 Glutamate ionotropic receptor NMDA type subunit 3A 9 101569353-101738580 FDA approved drug targets, Predicted membrane proteins Evidence at protein level Tissue enriched Group enriched 5 cerebral cortex: 12.3;cervix, uterine: 2.5 seminal vesicle: 1.3 Cell line enriched 6 SCLC-21H: 2.1 +MT-ND5 MTND5, NAD5, ND5 ENSG00000198786 Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 MT 12337-14148 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Renal cancer:7.31e-5 (favourable) Expressed in all Expressed in all heart muscle: 13037.2 Expressed in all +CNOT7 CAF1 ENSG00000198791 CCR4-NOT transcription complex subunit 7 8 17224964-17246878 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069543 Supported Nuclear bodies Colorectal cancer:4.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 112.7 Expressed in all +TMEM184B C22orf5, DKFZP586A1024, FM08, HS5O6A ENSG00000198792 Transmembrane protein 184B 22 38219291-38273034 Predicted membrane proteins, Transporters Evidence at protein level HPA024076 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:5.94e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 57.4 Expressed in all +MTOR FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 ENSG00000198793 Mechanistic target of rapamycin 1 11106535-11262507 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB069425, HPA071227 Approved Approved Vesicles
Cytosol Renal cancer:1.49e-5 (favourable) Expressed in all Expressed in all testis: 62.2 Expressed in all +SCAMP5 MGC24969 ENSG00000198794 Secretory carrier membrane protein 5 15 74957219-75021496 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046645 Enhanced Renal cancer:1.34e-6 (favourable), Pancreatic cancer:5.67e-5 (favourable) Expressed in all Tissue enhanced cerebral cortex: 275.5 parathyroid gland: 81.7 Cell line enhanced SCLC-21H: 103.1;SH-SY5Y: 51.9 +ZNF521 EHZF, Evi3 ENSG00000198795 Zinc finger protein 521 18 25061926-25352190 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023056, HPA023849 Enhanced Approved Nucleoplasm Mixed Mixed spleen: 29.0 Cell line enhanced AF22: 66.8;HUVEC TERT2: 39.1 +ALPK2 HAK ENSG00000198796 Alpha kinase 2 18 58481247-58628957 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA027377, HPA027976, HPA028084, HPA029801 Uncertain Approved Cytosol Renal cancer:8.20e-5 (unfavourable) Tissue enriched Tissue enhanced heart muscle: 28.6;skeletal muscle: 14.1 lymph node: 6.9 Cell line enhanced BJ: 44.5;BJ hTERT+: 25.8;fHDF/TERT166: 37.1;U-138 MG: 25.6 +BRINP2 DBCCR1L2, FAM5B ENSG00000198797 BMP/retinoic acid inducible neural specific 2 1 177171497-177282422 Predicted secreted proteins, Transporters Evidence at transcript level HPA050681, HPA061920 Uncertain Approved Nucleoli
Vesicles Tissue enriched Group enriched 10 adrenal gland: 11.5;cerebral cortex: 35.4 testis: 2.3 Group enriched 5 HDLM-2: 6.7;PC-3: 1.6;REH: 1.8;SCLC-21H: 7.3;SH-SY5Y: 1.4 +MAGEB3 CT3.5 ENSG00000198798 MAGE family member B3 X 30230436-30237492 Predicted intracellular proteins Evidence at protein level HPA072203 Approved Not detected Group enriched 156 epididymis: 21.5;testis: 9.5 all non-specific tissues: 0.0 Cell line enriched 10 U-266/70: 1.6 +LRIG2 KIAA0806 ENSG00000198799 Leucine rich repeats and immunoglobulin like domains 2 1 113073209-113132260 Disease related genes, Predicted membrane proteins Evidence at protein level HPA015538 Uncertain Approved Nucleus
Golgi apparatus Endometrial cancer:9.37e-4 (unfavourable) Expressed in all Mixed parathyroid gland,thyroid gland: 5.6 Mixed +MT-CO1 COI, COX1, MTCO1 ENSG00000198804 Mitochondrially encoded cytochrome c oxidase I MT 5904-7445 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB016241, HPA069328 Enhanced Supported Mitochondria Liver cancer:2.29e-4 (favourable) Expressed in all Expressed in all heart muscle: 79421.5 Expressed in all +PNP NP, PUNP ENSG00000198805 Purine nucleoside phosphorylase 14 20468954-20477094 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001625 Enhanced Supported Cytosol Renal cancer:2.24e-4 (favourable), Liver cancer:4.43e-4 (unfavourable) Expressed in all Expressed in all epididymis: 698.2 Expressed in all +PAX9 ENSG00000198807 Paired box 9 14 36657568-36679715 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038462 Enhanced Approved Nucleoplasm
Mitochondria Cervical cancer:5.38e-4 (favourable) Mixed Group enriched 8 esophagus: 56.1;parathyroid gland: 102.3;salivary gland: 21.7 tonsil: 7.5 Cell line enhanced HDLM-2: 44.7;PC-3: 18.6 +LRRC10 HRLRRP, LRRC10A ENSG00000198812 Leucine rich repeat containing 10 12 69608564-69611162 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 28 heart muscle: 22.6 lymph node: 0.7 Not detected +GK GK1, GKD ENSG00000198814 Glycerol kinase X 30653359-30731456 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060687 Supported Renal cancer:3.24e-9 (favourable) Expressed in all Tissue enhanced kidney: 111.0 small intestine: 98.6 Mixed +FOXJ3 KIAA1041 ENSG00000198815 Forkhead box J3 1 42176539-42335877 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067284 Approved Nucleoplasm
Nuclear speckles
Vesicles Renal cancer:4.51e-7 (unfavourable), Liver cancer:5.17e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 40.1 Expressed in all +ZNF358 FLJ10390, ZFEND ENSG00000198816 Zinc finger protein 358 19 7515292-7521026 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030887, HPA063624 Approved Approved Nucleus Pancreatic cancer:2.50e-4 (favourable) Expressed in all Expressed in all ovary: 84.0 Mixed +SFT2D1 C6orf83, MGC19825, pRGR1 ENSG00000198818 SFT2 domain containing 1 6 166319728-166342591 Predicted membrane proteins Evidence at protein level HPA014677 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:2.19e-5 (unfavourable), Renal cancer:3.59e-4 (unfavourable), Thyroid cancer:5.90e-4 (favourable), Head and neck cancer:7.47e-4 (unfavourable) Expressed in all Expressed in all epididymis: 78.5 Expressed in all +CD247 CD3H, CD3Q, CD3Z ENSG00000198821 CD247 molecule 1 167430640-167518610 CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB004651, HPA008750 Enhanced Endometrial cancer:8.63e-6 (favourable), Renal cancer:9.94e-6 (unfavourable), Head and neck cancer:3.98e-4 (favourable), Breast cancer:9.12e-4 (favourable) Mixed Tissue enhanced lymph node: 65.1;spleen: 48.6 tonsil: 33.6 Group enriched 34 HDLM-2: 144.2;MOLT-4: 133.0 +GRM3 GPRC1C, mGlu3, MGLUR3 ENSG00000198822 Glutamate metabotropic receptor 3 7 86643914-86864884 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 43 cerebral cortex: 62.3 testis: 1.4 Cell line enriched 8 AF22: 35.5 +CHAMP1 C13orf8, CAMP, CHAMP, ZNF828 ENSG00000198824 Chromosome alignment maintaining phosphoprotein 1 13 114314513-114327328 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA006623, HPA008900 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all lymph node: 19.3 Expressed in all +INPP5F hSac2, KIAA0966, SAC2 ENSG00000198825 Inositol polyphosphate-5-phosphatase F 10 119726097-119829278 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all cerebral cortex: 132.0 Expressed in all +ARHGAP11A KIAA0013 ENSG00000198826 Rho GTPase activating protein 11A 15 32615144-32639949 Predicted intracellular proteins Evidence at protein level HPA040419, HPA040830 Enhanced Approved Nucleoli
Cytosol Pancreatic cancer:2.92e-5 (unfavourable), Liver cancer:2.05e-4 (unfavourable), Lung cancer:8.69e-4 (unfavourable) Expressed in all Mixed lymph node,testis: 15.7 Expressed in all +SUCNR1 GPR91 ENSG00000198829 Succinate receptor 1 3 151873643-151884619 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB022745 Uncertain Mixed Tissue enhanced kidney: 42.3 thyroid gland: 15.9 Group enriched 6 HEL: 47.7;NB-4: 19.6;U-937: 41.3 +HMGN2 HMG17 ENSG00000198830 High mobility group nucleosomal binding domain 2 1 26472450-26475972 Predicted intracellular proteins Evidence at protein level CAB018371, HPA077364 Supported Supported Nucleus Liver cancer:1.34e-4 (unfavourable), Renal cancer:3.92e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 782.8 Expressed in all +SELENOM SELM, SEPM ENSG00000198832 Selenoprotein M 22 31104772-31120069 Predicted secreted proteins Evidence at protein level CAB008667, HPA019601 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.55e-6 (unfavourable) Expressed in all Expressed in all seminal vesicle: 200.8 Cell line enhanced HHSteC: 154.4 +UBE2J1 CGI-76, HSPC153, NCUBE1, UBC6 ENSG00000198833 Ubiquitin conjugating enzyme E2 J1 6 89326625-89352848 Enzymes, Predicted membrane proteins Evidence at protein level HPA003509, CAB073419 Enhanced Liver cancer:6.90e-5 (unfavourable), Renal cancer:1.11e-4 (unfavourable), Endometrial cancer:2.87e-4 (favourable), Ovarian cancer:7.43e-4 (favourable) Expressed in all Expressed in all lymph node: 102.3 Mixed +GJC2 CX46.6, CX47, GJA12, SPG44 ENSG00000198835 Gap junction protein gamma 2 1 228149852-228159826 Disease related genes, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced cerebral cortex: 11.5 fallopian tube: 3.7 Cell line enhanced EFO-21: 5.1;SCLC-21H: 3.4 +OPA1 FLJ12460, KIAA0567, MGM1, NPG, NTG ENSG00000198836 OPA1, mitochondrial dynamin like GTPase 3 193593144-193697823 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA036926, HPA036927 Enhanced Supported Nucleoplasm
Mitochondria Pancreatic cancer:8.44e-5 (unfavourable), Renal cancer:1.84e-4 (favourable), Endometrial cancer:8.61e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 56.2 Expressed in all +DENND4B KIAA0476 ENSG00000198837 DENN domain containing 4B 1 153929501-153946696 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040188, HPA071133 Approved Approved Nucleus
Golgi apparatus Renal cancer:9.27e-9 (unfavourable), Pancreatic cancer:3.18e-5 (favourable), Liver cancer:4.14e-4 (unfavourable) Expressed in all Expressed in all spleen: 40.2 Expressed in all +RYR3 ENSG00000198838 Ryanodine receptor 3 15 33310945-33866121 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA062004 Approved Vesicles Tissue enhanced Tissue enhanced parathyroid gland: 29.1 cerebral cortex: 7.0 Cell line enhanced A549: 3.9;RH-30: 6.3;RPTEC TERT1: 2.3 +ZNF277 NRIF4, ZNF277P ENSG00000198839 Zinc finger protein 277 7 112206588-112343096 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027307 Uncertain Approved Nucleoplasm
Plasma membrane Renal cancer:9.47e-4 (favourable) Expressed in all Expressed in all thyroid gland: 33.4 Expressed in all +MT-ND3 MTND3, NAD3, ND3 ENSG00000198840 Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 MT 10059-10404 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA063296 Enhanced Approved Cytosol Liver cancer:4.63e-5 (favourable) Expressed in all Expressed in all heart muscle: 30083.4 Expressed in all +KTI12 MGC20419, SBBI81, TOT4 ENSG00000198841 KTI12 chromatin associated homolog 1 52032103-52033816 Predicted intracellular proteins Evidence at protein level HPA031203, HPA031204, HPA031205 Approved Approved Nuclear speckles
Cytoplasmic bodies Liver cancer:1.02e-4 (unfavourable) Expressed in all Mixed ovary: 11.5 Expressed in all +DUSP27 ENSG00000198842 Dual specificity phosphatase 27 (putative) 1 167094045-167129165 Predicted intracellular proteins Evidence at protein level HPA012608, HPA012912 Uncertain Approved Nucleoplasm Group enriched Group enriched 15 heart muscle: 41.9;skeletal muscle: 39.7 placenta,prostate: 2.6 Cell line enriched 11 RH-30: 13.7 +SELENOT SELT ENSG00000198843 Selenoprotein T 3 150602875-150630445 Predicted membrane proteins Evidence at protein level HPA039780 Approved Expressed in all Expressed in all thyroid gland: 109.3 Expressed in all +ARHGEF15 ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF ENSG00000198844 Rho guanine nucleotide exchange factor 15 17 8310241-8322516 Predicted intracellular proteins Evidence at protein level HPA044443, HPA063495 Supported Plasma membrane Expressed in all Tissue enhanced adipose tissue: 37.2 lung: 30.7 Group enriched 41 HUVEC TERT2: 32.7;TIME: 42.4 +TOX KIAA0808, TOX1 ENSG00000198846 Thymocyte selection associated high mobility group box 8 58805418-59119208 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018322, HPA073241 Enhanced Approved Nucleus
Nucleoli fibrillar center Renal cancer:1.90e-7 (unfavourable), Lung cancer:5.20e-4 (favourable) Expressed in all Mixed lymph node: 21.1 Cell line enhanced MOLT-4: 117.4;SH-SY5Y: 46.0 +CES1 CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1 ENSG00000198848 Carboxylesterase 1 16 55802851-55833337 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012023, HPA046717 Enhanced Enhanced Endoplasmic reticulum Urothelial cancer:9.92e-4 (unfavourable) Tissue enriched Group enriched 7 gallbladder: 399.2;liver: 1099.9;lung: 229.9 adipose tissue: 79.7 Group enriched 5 Hep G2: 414.0;THP-1: 439.1;U-937: 102.6 +CD3E ENSG00000198851 CD3e molecule 11 118304545-118316175 CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB000010, HPA040957, HPA043955, CAB072863, CAB072864 Enhanced Endometrial cancer:2.30e-6 (favourable), Renal cancer:1.12e-5 (unfavourable), Melanoma:1.18e-4 (favourable), Head and neck cancer:1.32e-4 (favourable), Cervical cancer:1.62e-4 (favourable), Breast cancer:1.72e-4 (favourable) Expressed in all Tissue enhanced lymph node: 200.5;tonsil: 113.4 spleen: 95.0 Cell line enriched 92 MOLT-4: 531.3 +RUSC2 KIAA0375 ENSG00000198853 RUN and SH3 domain containing 2 9 35490127-35561898 Predicted intracellular proteins Evidence at protein level HPA021297 Uncertain Expressed in all Expressed in all cerebral cortex: 48.5 Mixed +C1orf68 LEP7, XP32 ENSG00000198854 Chromosome 1 open reading frame 68 1 152719522-152720470 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enriched 14 skin: 806.5 breast: 57.5 Cell line enriched 6 HaCaT: 1.6 +FICD HIP13, HYPE ENSG00000198855 FIC domain containing 12 108515185-108525837 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021390, HPA071134 Approved Approved Nucleus Endometrial cancer:4.61e-5 (favourable) Expressed in all Mixed thyroid gland: 17.7 Mixed +OSTC DC2 ENSG00000198856 Oligosaccharyltransferase complex non-catalytic subunit 4 108650584-108667820 Predicted membrane proteins Evidence at protein level HPA065174 Approved Nucleoplasm Renal cancer:2.31e-8 (unfavourable), Endometrial cancer:1.44e-4 (favourable), Lung cancer:2.84e-4 (unfavourable), Head and neck cancer:6.66e-4 (unfavourable) Expressed in all Expressed in all epididymis: 215.1 Expressed in all +R3HDM4 C19orf22, MGC16353 ENSG00000198858 R3H domain containing 4 19 896503-913245 Predicted intracellular proteins Evidence at protein level HPA043025, HPA048638 Uncertain Approved Nucleus
Cytosol Endometrial cancer:7.33e-6 (favourable) Expressed in all Expressed in all appendix: 67.7 Expressed in all +TSEN15 C1orf19 ENSG00000198860 TRNA splicing endonuclease subunit 15 1 184051677-184074212 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029237 Approved Approved Nucleus
Nucleoli Renal cancer:3.66e-10 (unfavourable), Liver cancer:2.07e-5 (unfavourable), Ovarian cancer:4.59e-4 (favourable) Expressed in all Expressed in all thyroid gland: 34.8 Expressed in all +LTN1 C21orf10, C21orf98, FLJ11053, KIAA0714, LISTERIN, RNF160, ZNF294 ENSG00000198862 Listerin E3 ubiquitin protein ligase 1 21 28928144-28992956 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029143, CAB034164, HPA055604 Uncertain Enhanced Cytosol Expressed in all Expressed in all placenta: 26.6 Expressed in all +RUNDC1 DKFZp761H0421 ENSG00000198863 RUN domain containing 1 17 42980565-42993690 Predicted intracellular proteins Evidence at protein level HPA023726 Uncertain Approved Nuclear speckles
Cytosol Endometrial cancer:6.93e-5 (favourable) Expressed in all Expressed in all fallopian tube: 23.5 Expressed in all +CCDC152 LOC100129792 ENSG00000198865 Coiled-coil domain containing 152 5 42756801-42802360 Predicted intracellular proteins Evidence at protein level HPA036240 Approved Approved Nucleoplasm
Cytosol Mixed Mixed small intestine: 11.3 Cell line enhanced HeLa: 8.9;U-2 OS: 24.5;U-266/84: 11.8 +STKLD1 C9orf96, MGC43306, SGK071 ENSG00000198870 Serine/threonine kinase like domain containing 1 9 133376367-133406096 Enzymes, Predicted membrane proteins Evidence at transcript level HPA029902 Uncertain Mixed Tissue enriched 14 testis: 5.7 cerebral cortex,epididymis: 0.3 Not detected +GRK5 GPRK5 ENSG00000198873 G protein-coupled receptor kinase 5 10 119207589-119459742 Enzymes, Predicted intracellular proteins Evidence at protein level CAB025579, HPA046838 Approved Supported Nuclear membrane
Nuclear speckles
Plasma membrane Renal cancer:2.38e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 78.5 Cell line enhanced BJ hTERT+: 68.5;HUVEC TERT2: 55.7 +TYW1 FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W ENSG00000198874 TRNA-yW synthesizing protein 1 homolog 7 66995173-67239519 Enzymes, Predicted membrane proteins Evidence at protein level HPA013568, HPA014118, HPA015535, HPA043136, HPA047029, HPA047052, HPA052097 Approved Approved Nucleus
Nucleoli Ovarian cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.1 Expressed in all +DCAF12 CT102, DKFZP434O125, KIAA1892, MGC1058, TCC52, WDR40A ENSG00000198876 DDB1 and CUL4 associated factor 12 9 34086387-34127399 Predicted intracellular proteins Evidence at protein level HPA062279 Uncertain Ovarian cancer:2.81e-5 (favourable) Expressed in all Expressed in all testis: 113.2 Expressed in all +SFMBT2 KIAA1617 ENSG00000198879 Scm-like with four mbt domains 2 10 7158624-7411486 Predicted intracellular proteins Evidence at protein level HPA035447, HPA035448 Uncertain Supported Nuclear speckles Mixed Mixed parathyroid gland: 15.3 Cell line enhanced Karpas-707: 19.0;REH: 22.4;SH-SY5Y: 19.1;THP-1: 19.7 +ASB12 FLJ39577 ENSG00000198881 Ankyrin repeat and SOCS box containing 12 X 64224196-64230631 Predicted intracellular proteins Evidence at protein level HPA049542 Uncertain Mixed Tissue enriched 14 skeletal muscle: 30.7 fallopian tube: 2.2 Cell line enhanced AF22: 1.2 +PNMA5 KIAA1934 ENSG00000198883 Paraneoplastic Ma antigen family member 5 X 152988824-152994127 Predicted intracellular proteins Evidence at protein level HPA044690 Enhanced Colorectal cancer:2.25e-4 (unfavourable), Lung cancer:3.16e-4 (favourable) Mixed Group enriched 20 cerebral cortex: 8.1;testis: 16.3 skin,spleen: 0.5 Group enriched 495 HMC-1: 311.7;U-266/70: 426.0;U-266/84: 249.2 +ITPRIPL1 KIAA1754L ENSG00000198885 Inositol 1,4,5-trisphosphate receptor interacting protein-like 1 2 96325331-96330517 Predicted membrane proteins Evidence at protein level Mixed Tissue enriched 6 testis: 27.3 lymph node: 4.8 Mixed +MT-ND4 LHON, MTND4, NAD4, ND4 ENSG00000198886 Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 MT 10760-12137 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA053928 Approved Ovarian cancer:1.76e-4 (favourable) Expressed in all Expressed in all heart muscle: 36982.3 Expressed in all +SMC5 KIAA0594, SMC5L1 ENSG00000198887 Structural maintenance of chromosomes 5 9 70258962-70354888 Predicted intracellular proteins Evidence at protein level HPA054900 Enhanced Supported Nuclear speckles Expressed in all Expressed in all ovary: 30.8 Expressed in all +MT-ND1 MTND1, NAD1, ND1 ENSG00000198888 Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 MT 3307-4262 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB033779 Approved Pancreatic cancer:3.26e-4 (favourable), Breast cancer:3.63e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 23817.4 Expressed in all +DCAF12L1 KIAA1892L, WDR40B ENSG00000198889 DDB1 and CUL4 associated factor 12 like 1 X 126549383-126552851 Predicted intracellular proteins Evidence at protein level HPA044737, HPA048981, HPA053138 Approved Mixed Tissue enhanced epididymis: 5.9;testis: 11.4 fallopian tube: 4.0 Group enriched 21 EFO-21: 14.1;U-2 OS: 8.6 +PRMT6 FLJ10559, HRMT1L6 ENSG00000198890 Protein arginine methyltransferase 6 1 107056679-107059294 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059424 Approved Supported Nucleus
Nucleoli Endometrial cancer:3.05e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 17.2 Cell line enhanced MCF7: 235.5 +SHISA4 C1orf40, hShisa4, TMEM58 ENSG00000198892 Shisa family member 4 1 201888680-201892306 Predicted membrane proteins Evidence at protein level HPA061273 Uncertain Expressed in all Tissue enhanced cerebral cortex: 45.3;skeletal muscle: 94.4 adrenal gland: 23.6 Mixed +CIPC KIAA1737 ENSG00000198894 CLOCK interacting pacemaker 14 77098097-77117287 Predicted intracellular proteins Evidence at protein level HPA000644 Supported Nucleus
Nucleoli
Cytosol Renal cancer:1.77e-10 (favourable) Expressed in all Expressed in all cerebral cortex: 54.3 Expressed in all +CAPZA2 CAPPA2, CAPZ ENSG00000198898 Capping actin protein of muscle Z-line alpha subunit 2 7 116811070-116922049 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007470, HPA007643 Uncertain Approved Endoplasmic reticulum
Cytosol Renal cancer:3.65e-6 (favourable), Liver cancer:9.34e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 41.6 Expressed in all +MT-ATP6 ATP6, ATPase-6, MTATP6, RP, Su6m ENSG00000198899 Mitochondrially encoded ATP synthase 6 MT 8527-9207 Disease related genes, Predicted membrane proteins Evidence at protein level Liver cancer:3.79e-4 (favourable), Pancreatic cancer:7.64e-4 (favourable) Expressed in all Expressed in all heart muscle: 42788.3 Expressed in all +TOP1 ENSG00000198900 Topoisomerase (DNA) I 20 41028818-41124487 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB009058, HPA019039 Enhanced Supported Nucleus
Nucleoli fibrillar center Liver cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all placenta: 71.7 Expressed in all +PRC1 ASE1 ENSG00000198901 Protein regulator of cytokinesis 1 15 90966038-90995629 Predicted intracellular proteins Evidence at protein level HPA034521 Enhanced Renal cancer:0.00e+0 (unfavourable), Pancreatic cancer:2.76e-5 (unfavourable), Liver cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all testis: 85.8 Expressed in all +BHLHB9 GASP3, KIAA1701, p60TRP ENSG00000198908 Basic helix-loop-helix domain containing, class B, 9 X 102720688-102753540 Predicted intracellular proteins Evidence at protein level HPA000887 Supported Nucleoplasm
Cytosol Expressed in all Tissue enhanced cerebral cortex: 18.8 parathyroid gland: 8.4 Mixed +MAP3K3 MAPKKK3, MEKK3 ENSG00000198909 Mitogen-activated protein kinase kinase kinase 3 17 63622415-63696303 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007764, HPA035410, HPA035411 Uncertain Approved Nucleoplasm Endometrial cancer:1.13e-4 (unfavourable) Expressed in all Expressed in all spleen: 41.5 Expressed in all +L1CAM CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1 ENSG00000198910 L1 cell adhesion molecule X 153861514-153909223 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB010896 Enhanced Approved Nucleoplasm
Plasma membrane Endometrial cancer:8.51e-10 (unfavourable), Lung cancer:2.36e-6 (unfavourable), Renal cancer:1.17e-4 (unfavourable), Head and neck cancer:3.81e-4 (unfavourable) Tissue enhanced Tissue enhanced adrenal gland: 36.0;cerebral cortex: 66.9 seminal vesicle: 12.8 Cell line enhanced BJ hTERT+: 303.8;BJ hTERT+ SV40 Large T+ RasG12V: 195.5;HeLa: 182.1 +SREBF2 bHLHd2, SREBP2 ENSG00000198911 Sterol regulatory element binding transcription factor 2 22 41833079-41907308 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA031962, HPA031963 Approved Supported Nucleoplasm
Vesicles
Mitochondria Renal cancer:1.37e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 118.4 Expressed in all +C1orf174 RP13-531C17.2 ENSG00000198912 Chromosome 1 open reading frame 174 1 3889125-3900293 Predicted intracellular proteins Evidence at protein level HPA008270, HPA065778 Approved Enhanced Nucleus Renal cancer:2.73e-6 (unfavourable), Liver cancer:5.84e-4 (unfavourable), Melanoma:7.62e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 17.3 Expressed in all +POU3F3 BRN1, OTF8 ENSG00000198914 POU class 3 homeobox 3 2 104855511-104858574 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052792, HPA056039, HPA067151 Approved Enhanced Nucleus Endometrial cancer:4.26e-5 (unfavourable) Group enriched Group enriched 45 cerebral cortex: 43.9;epididymis: 46.3;kidney: 36.6;seminal vesicle: 23.2 skin: 0.8 Group enriched 5 AF22: 58.4;AN3-CA: 52.7;HEK 293: 20.3;RPTEC TERT1: 50.7;SH-SY5Y: 19.7 +RASGEF1A CG4853, FLJ37817 ENSG00000198915 RasGEF domain family member 1A 10 43194535-43266919 Predicted intracellular proteins Evidence at protein level HPA035593 Enhanced Approved Golgi apparatus Renal cancer:4.11e-7 (unfavourable), Breast cancer:1.86e-5 (favourable), Endometrial cancer:4.28e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 22.7 parathyroid gland: 12.8 Cell line enhanced K-562: 15.4;SCLC-21H: 18.4;T-47d: 14.7 +SPOUT1 C9orf114, CENP-32, HSPC109 ENSG00000198917 SPOUT domain containing methyltransferase 1 9 128819651-128829821 Predicted intracellular proteins Evidence at protein level HPA022990 Approved Nucleus
Nucleoli Pancreatic cancer:4.09e-4 (favourable) Expressed in all Expressed in all lymph node: 22.0 Expressed in all +RPL39 L39, RPL39P42 ENSG00000198918 Ribosomal protein L39 X 119786504-119791643 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047105 Uncertain Renal cancer:1.71e-9 (unfavourable) Expressed in all Expressed in all breast: 5369.7 Expressed in all +DZIP3 hRUL138, PPP1R66 ENSG00000198919 DAZ interacting zinc finger protein 3 3 108589682-108694846 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035066, HPA049232 Approved Approved Vesicles Renal cancer:3.65e-4 (favourable) Expressed in all Expressed in all testis: 65.7 Mixed +KIAA0753 MNR, OFIP ENSG00000198920 KIAA0753 17 6578148-6640927 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023057, HPA023494 Enhanced Enhanced Centrosome
Cytosol Expressed in all Mixed parathyroid gland: 33.2 Mixed +DCLRE1A hSNM1, KIAA0086, PSO2, SNM1 ENSG00000198924 DNA cross-link repair 1A 10 113834725-113854383 Predicted intracellular proteins Evidence at protein level HPA036907 Approved Supported Nucleoplasm
Nucleoli fibrillar center Liver cancer:5.74e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 13.4 Expressed in all +ATG9A APG9L1, FLJ22169 ENSG00000198925 Autophagy related 9A 2 219209772-219229717 Predicted membrane proteins Evidence at protein level HPA059551 Uncertain Supported Vesicles Liver cancer:2.18e-5 (unfavourable) Expressed in all Expressed in all testis: 113.1 Expressed in all +NOS1AP CAPON, KIAA0464 ENSG00000198929 Nitric oxide synthase 1 adaptor protein 1 162069774-162370475 Predicted intracellular proteins Evidence at protein level CAB018582, HPA030066, HPA055561 Approved Approved Nucleus
Vesicles Mixed Tissue enriched 6 cerebral cortex: 23.4 adrenal gland: 3.8 Cell line enhanced A-431: 3.6;HEL: 4.5 +CSAG1 CSAGE, CT24.1 ENSG00000198930 Chondrosarcoma associated gene 1 X 152727484-152733735 Predicted intracellular proteins Evidence at transcript level HPA078264 Approved Vesicles Mixed Tissue enhanced testis: 2.4 lymph node: 0.8 Cell line enhanced HMC-1: 57.5;K-562: 39.8;PC-3: 55.8;SH-SY5Y: 39.1;U-266/70: 79.2 +APRT ENSG00000198931 Adenine phosphoribosyltransferase 16 88809339-88811944 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026681 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all skin: 112.4 Expressed in all +GPRASP1 GASP, GASP1 ENSG00000198932 G protein-coupled receptor associated sorting protein 1 X 102651366-102659083 Predicted intracellular proteins Evidence at protein level HPA000161, HPA031061 Uncertain Supported Cytosol Pancreatic cancer:1.77e-5 (favourable), Thyroid cancer:7.38e-4 (unfavourable) Mixed Mixed cerebral cortex: 64.8 Cell line enhanced REH: 5.1 +TBKBP1 KIAA0775, ProSAPiP2 ENSG00000198933 TBK1 binding protein 1 17 47694081-47712050 Predicted intracellular proteins Evidence at protein level HPA062347, HPA064856 Approved Approved Nucleoplasm Pancreatic cancer:8.14e-6 (favourable), Urothelial cancer:1.59e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 32.9 Cell line enhanced CACO-2: 52.0 +MAGEE1 DAMAGE, KIAA1587 ENSG00000198934 MAGE family member E1 X 76427724-76431353 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003047 Approved Approved Cytokinetic bridge
Cytosol Renal cancer:6.86e-6 (favourable), Pancreatic cancer:3.95e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 29.8 parathyroid gland: 14.3 Mixed +CCDC167 C6orf129, dJ153P14.2 ENSG00000198937 Coiled-coil domain containing 167 6 37482920-37499922 Predicted membrane proteins Evidence at protein level HPA045215 Uncertain Approved Cytosol Renal cancer:1.71e-7 (unfavourable), Liver cancer:2.94e-4 (unfavourable), Cervical cancer:7.59e-4 (favourable) Expressed in all Expressed in all tonsil: 55.0 Cell line enriched 7 U-698: 913.2 +MT-CO3 CO3, COIII, COX3, MTCO3 ENSG00000198938 Mitochondrially encoded cytochrome c oxidase III MT 9207-9990 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA042788 Approved Approved Nucleoplasm Pancreatic cancer:1.04e-4 (favourable), Liver cancer:2.01e-4 (favourable) Expressed in all Expressed in all kidney: 54081.3 Expressed in all +ZFP2 FLJ21628, ZNF751 ENSG00000198939 ZFP2 zinc finger protein 5 178895894-178933212 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023364 Uncertain Mixed Mixed testis: 7.8 Cell line enhanced AN3-CA: 5.1;HAP1: 2.7 +SOWAHA ANKRD43 ENSG00000198944 Sosondowah ankyrin repeat domain family member A 5 132813587-132816797 Predicted secreted proteins Evidence at protein level HPA064621 Approved Renal cancer:9.38e-5 (favourable), Pancreatic cancer:4.03e-4 (favourable) Mixed Tissue enhanced duodenum: 39.7;small intestine: 46.6 cerebral cortex: 22.1 Group enriched 8 SCLC-21H: 17.0;T-47d: 32.7 +L3MBTL3 KIAA1798 ENSG00000198945 L(3)mbt-like 3 (Drosophila) 6 130013699-130141451 Predicted intracellular proteins Evidence at protein level HPA044382, HPA053035 Approved Enhanced Nucleus
Nucleoli Expressed in all Mixed endometrium: 18.5 Cell line enhanced HMC-1: 55.3;HUVEC TERT2: 52.0 +DMD BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85 ENSG00000198947 Dystrophin X 31097677-33339441 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level CAB000119, HPA002725, HPA023885 Enhanced Mixed Mixed seminal vesicle: 54.6 Cell line enhanced AF22: 25.1;RH-30: 31.0 +MFAP3L KIAA0626, NYD-sp9 ENSG00000198948 Microfibrillar associated protein 3 like 4 169986597-170033031 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017986 Approved Renal cancer:1.42e-8 (favourable) Expressed in all Tissue enhanced testis: 74.1 epididymis: 47.4 Cell line enhanced HMC-1: 19.9;RT4: 30.4;SK-BR-3: 25.8 +NAGA D22S674 ENSG00000198951 Alpha-N-acetylgalactosaminidase 22 42058354-42070842 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA000649 Enhanced Expressed in all Expressed in all parathyroid gland: 63.7 Expressed in all +SMG5 EST1B, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5 ENSG00000198952 SMG5, nonsense mediated mRNA decay factor 1 156249224-156282825 Predicted membrane proteins Evidence at protein level HPA072651 Uncertain Cytoplasmic bodies Liver cancer:6.70e-9 (unfavourable), Endometrial cancer:3.39e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 76.0 Expressed in all +KIF1BP DKFZP586B0923, KBP, KIAA1279, TTC20 ENSG00000198954 KIF1 binding protein 10 68988721-69043544 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035538, HPA035539 Uncertain Renal cancer:2.60e-4 (favourable) Expressed in all Mixed cerebral cortex: 34.8 Mixed +TGM2 TGC ENSG00000198959 Transglutaminase 2 20 38127387-38166578 Enzymes, Predicted intracellular proteins Evidence at protein level CAB002598, HPA021019, HPA029518 Enhanced Approved Plasma membrane
Cytosol Renal cancer:1.67e-7 (unfavourable), Pancreatic cancer:2.97e-4 (unfavourable) Expressed in all Tissue enhanced cervix, uterine: 461.0 placenta: 319.8 Cell line enhanced CAPAN-2: 1300.3;EFO-21: 458.7;HUVEC TERT2: 559.8;TIME: 720.5 +ARMCX6 FLJ20811, GASP10 ENSG00000198960 Armadillo repeat containing, X-linked 6 X 101615118-101618001 Predicted membrane proteins Evidence at protein level HPA043030, HPA048125 Approved Supported Nucleus
Nuclear membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 33.8 Mixed +PJA2 KIAA0438, Neurodap1, RNF131 ENSG00000198961 Praja ring finger ubiquitin ligase 2 5 109334709-109409994 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040347, HPA057636 Enhanced Supported Intermediate filaments Ovarian cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 254.4 Expressed in all +RORB NR1F2, ROR-BETA, RZRB ENSG00000198963 RAR related orphan receptor B 9 74497365-74693177 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008393 Uncertain Approved Nucleus Group enriched Tissue enhanced cerebral cortex: 12.6;cervix, uterine: 14.1 prostate: 7.4 Cell line enhanced HHSteC: 18.9;HSkMC: 9.0;MOLT-4: 5.5;SH-SY5Y: 14.3 +SGMS1 MGC17342, MOB, SMS1, TMEM23 ENSG00000198964 Sphingomyelin synthase 1 10 50305586-50625163 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045191 Approved Approved Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus
Cytosol Renal cancer:1.95e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 116.7 Expressed in all +OR10R2 OR10R2Q ENSG00000198965 Olfactory receptor family 10 subfamily R member 2 1 158479878-158480885 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA059775, HPA060399 Uncertain Not detected Not detected thyroid gland: 0.1 Cell line enriched 9 MOLT-4: 26.2 +OR10Z1 ENSG00000198967 Olfactory receptor family 10 subfamily Z member 1 1 158606439-158607380 G-protein coupled receptors, Predicted membrane proteins No evidence HPA058072 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF525 KIAA1979 ENSG00000203326 Zinc finger protein 525 19 53365693-53392217 Predicted intracellular proteins Evidence at transcript level Mixed Mixed parathyroid gland: 20.7 Mixed +INF2 C14orf151, C14orf173, MGC13251 ENSG00000203485 Inverted formin, FH2 and WH2 domain containing 14 104689606-104722535 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000724 Approved Approved Nuclear bodies
Endoplasmic reticulum Liver cancer:8.18e-4 (unfavourable) Expressed in all Expressed in all stomach: 55.6 Expressed in all +FAM83H-AS1 onco-lncRNA-3 ENSG00000203499 FAM83H antisense RNA 1 (head to head) 8 143734140-143790644 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced epididymis: 26.2;skin: 34.3 esophagus: 13.0 Cell line enhanced HaCaT: 26.1;hTCEpi: 25.7;MCF7: 55.1;T-47d: 60.5 +RP11-176H8.1 ENSG00000203546 14 31334312-31457441 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced adipose tissue: 1.1 skeletal muscle: 0.4 Not detected +GP1BB CD42c, GPIbbeta ENSG00000203618 Glycoprotein Ib platelet beta subunit 22 19722945-19724771 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 6 skin: 2.8 spleen: 0.4 Cell line enhanced K-562: 8.8;NB-4: 5.1;REH: 8.9;SH-SY5Y: 4.7;U-2 OS: 9.7 +OR2T5 ENSG00000203661 Olfactory receptor family 2 subfamily T member 5 1 248488589-248489536 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR2L2 HSHTPCRH07, HTPCRH07, OR2L12, OR2L4P ENSG00000203663 Olfactory receptor family 2 subfamily L member 2 1 248038268-248039206 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 7 testis: 2.6 cerebral cortex,spleen: 0.3 Not detected +EFCAB2 CFAP200, DRC8, MGC12458 ENSG00000203666 EF-hand calcium binding domain 2 1 244969705-245127164 Predicted intracellular proteins Evidence at protein level HPA031206, HPA031207 Approved Approved Plasma membrane
Cytosol Thyroid cancer:6.51e-4 (unfavourable) Mixed Expressed in all fallopian tube: 57.7 Expressed in all +COX20 FAM36A, FLJ43269 ENSG00000203667 COX20, cytochrome c oxidase assembly factor 1 244835322-244845057 Predicted membrane proteins Evidence at protein level HPA043617, HPA045490 Approved Enhanced Mitochondria Ovarian cancer:3.13e-4 (favourable) Expressed in all Expressed in all adrenal gland: 51.7 Expressed in all +CHML REP-2 ENSG00000203668 CHM like, Rab escort protein 2 1 241628853-241640254 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029627, HPA029628, HPA062967 Supported Supported Nucleoplasm
Cytosol Liver cancer:9.23e-5 (unfavourable) Expressed in all Mixed placenta: 16.6 Expressed in all +STUM C1orf95, DKFZp761P211 ENSG00000203685 Stum, mechanosensory transduction mediator homolog 1 226548800-226609214 Predicted membrane proteins Evidence at protein level HPA074381 Approved Cytosol Renal cancer:6.40e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 35.7 smooth muscle: 8.4 Cell line enriched 5 HEL: 26.9 +TCP10 ENSG00000203690 T-complex 10 6 167357031-167384510 Predicted intracellular proteins Evidence at transcript level HPA044709 Approved Not detected Tissue enriched 14 testis: 14.1 small intestine: 0.9 Not detected +CAPN8 nCL-2 ENSG00000203697 Calpain 8 1 223538007-223665734 Enzymes, Predicted intracellular proteins Evidence at protein level HPA073939 Approved Nucleoplasm
Nuclear membrane
Vesicles Tissue enhanced Tissue enriched 8 stomach: 286.5 rectum: 37.3 Cell line enriched 9 RT4: 62.5 +TATDN3 ENSG00000203705 TatD DNase domain containing 3 1 212791828-212816626 Predicted intracellular proteins Evidence at protein level HPA032092 Approved Approved Nucleoplasm
Golgi apparatus
Focal adhesion sites Renal cancer:1.59e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 22.1 Expressed in all +CR1 CD35, KN ENSG00000203710 Complement C3b/C4b receptor 1 (Knops blood group) 1 207496147-207640647 Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002491, CAB016271, HPA042455, HPA043579, HPA049348 Enhanced Mixed Tissue enhanced appendix: 37.5;spleen: 33.6 lymph node: 23.4 Group enriched 8 HL-60: 7.8;HMC-1: 19.1;NB-4: 5.8 +RAET1G ULBP5 ENSG00000203722 Retinoic acid early transcript 1G 6 149916878-149923121 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA062673 Approved Vesicles Lung cancer:5.35e-4 (unfavourable) Mixed Tissue enhanced adrenal gland: 8.2;esophagus: 9.5 skin: 3.4 Cell line enhanced HeLa: 21.4;hTCEpi: 18.1;SiHa: 13.3;U-87 MG: 9.8 +C1orf53 ENSG00000203724 Chromosome 1 open reading frame 53 1 197902647-197907367 Predicted intracellular proteins Evidence at protein level HPA065352 Approved Vesicles
Aggresome Breast cancer:1.63e-4 (favourable), Endometrial cancer:3.78e-4 (unfavourable) Expressed in all Mixed adrenal gland: 6.2 Mixed +SAMD5 dJ875H10.1 ENSG00000203727 Sterile alpha motif domain containing 5 6 147508927-147737547 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067811 Uncertain Supported Vesicles Liver cancer:2.23e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 22.5 placenta: 18.1 Cell line enhanced Hep G2: 44.5;K-562: 40.0;RH-30: 28.7;WM-115: 20.8 +TEDDM1 EDDM9, Epdd1, HE9, TMEM45C ENSG00000203730 Transmembrane epididymal protein 1 1 182398117-182400616 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 447 epididymis: 716.9 seminal vesicle: 1.6 Not detected +GJE1 CX23 ENSG00000203733 Gap junction protein epsilon 1 6 142133090-142135151 Predicted membrane proteins No evidence HPA014916 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +ECT2L ARHGEF32, C6orf91, FBXO49, LFDH ENSG00000203734 Epithelial cell transforming 2 like 6 138795926-138904070 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA035488 Uncertain Not detected Tissue enriched 7 fallopian tube: 18.3 lung: 2.7 Not detected +GPR52 ENSG00000203737 G protein-coupled receptor 52 1 174448111-174449198 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA028575 Uncertain Not detected Tissue enriched 7 cerebral cortex: 2.6 bone marrow: 0.3 Not detected +METTL11B C1orf184, HOMT1B ENSG00000203740 Methyltransferase like 11B 1 170146001-170167790 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028049 Uncertain Not detected Tissue enhanced heart muscle: 1.5 skeletal muscle,testis: 0.4 Cell line enriched 13 NTERA-2: 1.7 +FCGR3A CD16, CD16a, FCG3, FCGR3 ENSG00000203747 Fc fragment of IgG receptor IIIa 1 161541759-161550737 CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB032435, HPA055431 Supported Renal cancer:3.22e-6 (unfavourable) Expressed in all Expressed in all spleen: 419.4 Not detected +TMEM244 bA174C7.4, C6orf191 ENSG00000203756 Transmembrane protein 244 6 129831244-129861547 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 1.7 lymph node: 0.6 Cell line enhanced HDLM-2: 4.4;LHCN-M2: 4.4;U-251 MG: 3.4;U-266/70: 2.9;WM-115: 2.6 +OR6K3 ENSG00000203757 Olfactory receptor family 6 subfamily K member 3 1 158717168-158718163 G-protein coupled receptors, Predicted membrane proteins No evidence HPA055949 Uncertain Not detected Not detected bone marrow: 0.8 Not detected +CENPW C6orf173, CUG2 ENSG00000203760 Centromere protein W 6 126340174-126348875 Predicted intracellular proteins Evidence at protein level HPA067285 Supported Nucleoplasm Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.21e-5 (unfavourable) Expressed in all Mixed testis: 51.9 Expressed in all +SPRN bA108K14.1, FLJ41197, Shadoo, Sprn ENSG00000203772 Shadow of prion protein homolog (zebrafish) 10 133420666-133424572 Predicted secreted proteins, Transporters Evidence at transcript level Urothelial cancer:1.58e-7 (favourable), Pancreatic cancer:1.54e-6 (favourable), Renal cancer:3.95e-4 (unfavourable) Expressed in all Tissue enriched 9 cerebral cortex: 24.8 testis: 2.8 Mixed +FAM229B C6orf225, DKFZp586F0922, LOC619208 ENSG00000203778 Family with sequence similarity 229 member B 6 112087599-112102790 Predicted intracellular proteins Evidence at transcript level HPA036068 Approved Nucleus
Nucleoli
Golgi apparatus Renal cancer:8.76e-4 (favourable) Expressed in all Tissue enriched 6 testis: 542.3 fallopian tube: 85.3 Mixed +FANK1 ENSG00000203780 Fibronectin type III and ankyrin repeat domains 1 10 125896539-126009592 Predicted intracellular proteins Evidence at protein level HPA038413 Supported Nucleoplasm Endometrial cancer:3.83e-4 (favourable) Mixed Group enriched 5 fallopian tube: 55.3;testis: 92.6 epididymis: 14.3 Cell line enhanced CAPAN-2: 16.8;RPTEC TERT1: 10.1 +LOR ENSG00000203782 Loricrin 1 153259700-153262122 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA076123, HPA077266 Enhanced Head and neck cancer:8.53e-4 (favourable) Tissue enriched Tissue enriched 16 skin: 532.0 breast: 32.9 Cell line enriched 83 HDLM-2: 33.1 +PRR9 ENSG00000203783 Proline rich 9 1 153217584-153219317 Predicted intracellular proteins Evidence at transcript level HPA027714 Approved Group enriched Tissue enriched 5 testis: 2.8 breast,placenta: 0.5 Cell line enhanced HaCaT: 1.9;U-87 MG: 1.6 +LELP1 ENSG00000203784 Late cornified envelope like proline rich 1 1 153203443-153205120 Predicted intracellular proteins Evidence at protein level HPA070231 Enhanced Tissue enriched Tissue enriched 2787 testis: 784.3 seminal vesicle,small intestine: 0.2 Not detected +SPRR2E ENSG00000203785 Small proline rich protein 2E 1 153093135-153106184 Predicted intracellular proteins Evidence at transcript level Urothelial cancer:9.47e-4 (unfavourable) Tissue enhanced Group enriched 18 esophagus: 2005.4;skin: 804.8;tonsil: 459.7 breast: 61.4 Cell line enriched 9 hTCEpi: 12.1 +KPRP C1orf45 ENSG00000203786 Keratinocyte proline rich protein 1 152759561-152762052 Predicted intracellular proteins Evidence at protein level HPA031988, HPA031990 Enhanced Group enriched Tissue enriched 19 skin: 267.5 breast: 13.8 Cell line enhanced hTEC/SVTERT24-B: 1.9;U-2197: 1.1 +METTL10 C10orf138, Em:AC068896.3 ENSG00000203791 Methyltransferase like 10 10 124748149-124791870 Predicted intracellular proteins Evidence at protein level HPA050138 Approved Approved Nucleoplasm
Nuclear bodies Thyroid cancer:2.53e-4 (unfavourable), Prostate cancer:4.82e-4 (unfavourable) Expressed in all Mixed thyroid gland: 15.1 Expressed in all +FAM24A AC073585.4 ENSG00000203795 Family with sequence similarity 24 member A 10 122910701-122913111 Predicted intracellular proteins Evidence at protein level HPA052490 Supported Not detected Tissue enriched 332 testis: 33.1 all non-specific tissues: 0.0 Not detected +DDO ENSG00000203797 D-aspartate oxidase 6 110391771-110415562 Enzymes, Predicted membrane proteins Evidence at protein level HPA037525, HPA037526 Enhanced Supported Cytosol Renal cancer:8.69e-5 (favourable) Mixed Tissue enhanced parathyroid gland: 24.3 heart muscle: 12.2 Cell line enhanced RPMI-8226: 10.9;U-937: 13.6 +PLPP4 DPPL2, PPAPDC1, PPAPDC1A ENSG00000203805 Phospholipid phosphatase 4 10 120456954-120589855 Enzymes, Predicted membrane proteins Evidence at protein level HPA045188 Approved Approved Nucleus
Nucleoli Mixed Tissue enhanced cerebral cortex: 17.1;gallbladder: 10.4;testis: 12.7 kidney: 7.8 Cell line enhanced BJ: 30.3;U-251 MG: 92.6 +HIST2H3C H3, H3.2, H3/m, H3F2, H3FM, MGC9629 ENSG00000203811 Histone cluster 2 H3 family member c 1 149839538-149841193 Predicted intracellular proteins Evidence at protein level HPA042570, CAB069990 Supported Not detected Not detected cerebral cortex: 0.9 Cell line enhanced SiHa: 5.9 +HIST2H2AA3 H2A.2, H2A/q, H2AFO, HIST2H2AA ENSG00000203812 Histone cluster 2 H2A family member a3 1 149842188-149842736 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Tissue enhanced Tissue enhanced bone marrow: 112.2;prostate: 125.6 spleen: 42.0 Cell line enhanced U-266/70: 350.1;U-266/84: 191.4 +HIST2H2BF ENSG00000203814 Histone cluster 2 H2B family member f 1 149782689-149812373 Predicted intracellular proteins Evidence at protein level CAB007814, HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed Mixed ovary: 24.3 Cell line enhanced U-266/70: 38.0 +HIST2H3PS2 p06 ENSG00000203818 Histone cluster 2 H3 pseudogene 2 1 143905556-143905966 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Not detected Tissue enhanced adrenal gland: 8.5;spleen: 7.7 ovary: 5.8 Cell line enhanced BJ: 6.7;NB-4: 5.8;SH-SY5Y: 10.0;THP-1: 6.3;U-2197: 6.2 +PNLIPRP3 ENSG00000203837 Pancreatic lipase related protein 3 10 116427867-116477957 Enzymes, Predicted secreted proteins Evidence at transcript level HPA046202, HPA052009 Uncertain Tissue enhanced Tissue enhanced breast: 12.0;skin: 5.4 esophagus: 1.8 Cell line enriched 14 hTCEpi: 233.8 +HIST2H3A H3/n, H3/o ENSG00000203852 Histone cluster 2 H3 family member a 1 149852619-149854274 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Not detected Not detected cerebral cortex: 0.9 Cell line enhanced SiHa: 5.9 +HSD3B1 HSD3B, HSDB3, SDR11E1 ENSG00000203857 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1 119507198-119515054 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043261, HPA043264, HPA044028 Supported Urothelial cancer:4.59e-5 (favourable) Tissue enhanced Tissue enriched 13 placenta: 110.5 small intestine: 8.7 Cell line enriched 7 CACO-2: 52.9 +HSD3B2 SDR11E2 ENSG00000203859 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 1 119414931-119423035 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043261, HPA043264, HPA044028 Supported Tissue enhanced Tissue enriched 433 adrenal gland: 2384.5 testis: 5.5 Cell line enhanced SK-MEL-30: 1.2 +RBM20 ENSG00000203867 RNA binding motif protein 20 10 110644397-110839469 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035806, HPA037703 Uncertain Approved Nucleus
Nucleoli
Golgi apparatus
Cytokinetic bridge Mixed Tissue enhanced heart muscle: 26.4 skeletal muscle: 5.4 Cell line enhanced HEK 293: 5.5;RH-30: 15.9;SH-SY5Y: 16.0;T-47d: 8.7 +SMIM9 CXorf68 ENSG00000203870 Small integral membrane protein 9 X 154823348-154834662 Predicted membrane proteins Evidence at transcript level HPA060970 Uncertain Not detected Tissue enriched 5 testis: 1.3 placenta: 0.2 Not detected +C6orf163 ENSG00000203872 Chromosome 6 open reading frame 163 6 87344849-87365463 Predicted intracellular proteins Evidence at protein level HPA044797, HPA052927 Uncertain Uncertain Nucleoplasm Mixed Tissue enriched 6 testis: 14.0 fallopian tube: 2.4 Mixed +RIPPLY2 C6orf159, dJ237I15.1 ENSG00000203877 Ripply transcriptional repressor 2 6 83853266-83857515 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047454 Uncertain Tissue enhanced Tissue enriched 8 cerebral cortex: 14.9 adrenal gland: 1.8 Cell line enhanced SCLC-21H: 30.7;SH-SY5Y: 18.9 +GDI1 FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGDIA, XAP-4 ENSG00000203879 GDP dissociation inhibitor 1 X 154436913-154443467 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012979, HPA049290, HPA057668 Enhanced Approved Vesicles Colorectal cancer:3.83e-5 (unfavourable), Breast cancer:6.84e-4 (unfavourable) Expressed in all Tissue enriched 5 cerebral cortex: 532.0 smooth muscle: 101.3 Expressed in all +PCMTD2 C20orf36, FLJ10883 ENSG00000203880 Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 20 64255695-64287821 Predicted intracellular proteins Evidence at protein level HPA057849 Approved Approved Nucleoplasm
Mitochondria Lung cancer:2.13e-4 (favourable), Renal cancer:3.82e-4 (favourable) Expressed in all Expressed in all skin: 78.7 Expressed in all +SOX18 ENSG00000203883 SRY-box 18 20 64047582-64049641 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA073703 Approved Nucleus Expressed in all Tissue enhanced adipose tissue: 32.9 lung: 12.0 Cell line enhanced HUVEC TERT2: 17.4;NB-4: 22.5;REH: 7.7;TIME: 7.8 +LIME1 dJ583P15.4, FLJ20406, LIME ENSG00000203896 Lck interacting transmembrane adaptor 1 20 63736283-63739103 Predicted secreted proteins Evidence at protein level CAB015363 Approved Urothelial cancer:6.92e-6 (favourable), Renal cancer:5.04e-5 (unfavourable) Expressed in all Tissue enhanced liver: 19.6;stomach: 17.6 kidney: 15.2 Cell line enhanced MOLT-4: 31.1;RPMI-8226: 97.2;U-266/70: 55.2 +OOEP C6orf156, Em:AC019205.2, KHDC2 ENSG00000203907 Oocyte expressed protein 6 73368555-73395133 Predicted intracellular proteins Evidence at protein level HPA055165 Approved Tissue enriched Tissue enriched 11 testis: 23.1 placenta: 2.0 Cell line enhanced BEWO: 2.5;CAPAN-2: 7.2;MCF7: 2.1;U-2 OS: 1.8 +KHDC3L C6orf221, ECAT1 ENSG00000203908 KH domain containing 3 like, subcortical maternal complex member 6 73362677-73364171 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043699 Uncertain Tissue enriched Tissue enhanced lung: 1.0;testis: 2.2 epididymis: 0.4 Not detected +DPPA5 Esg1 ENSG00000203909 Developmental pluripotency associated 5 6 73353062-73354295 Predicted intracellular proteins Evidence at transcript level HPA064505 Uncertain Tissue enriched Tissue enhanced testis: 3.9 lung: 0.9 Not detected +C1orf146 ENSG00000203910 Chromosome 1 open reading frame 146 1 92217940-92245813 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 14 testis: 14.5 skin: 1.0 Not detected +SPANXN1 CT11.6, SPANX-N1 ENSG00000203923 SPANX family member N1 X 145246828-145256112 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 14 testis: 1.3 all non-specific tissues: 0.0 Not detected +SPANXA2 SPANX ENSG00000203926 SPANX family member A2 X 141589435-141590772 Predicted intracellular proteins Evidence at protein level HPA046423, HPA073647 Supported Supported Nucleoplasm
Vesicles Not detected Tissue enriched 93 testis: 9.2 all non-specific tissues: 0.0 Cell line enhanced U-2 OS: 1.6 +CXorf66 RP11-35F15.2, SGPX ENSG00000203933 Chromosome X open reading frame 66 X 139955725-139965520 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 76 testis: 24.3 liver: 0.3 Not detected +C10orf62 bA548K23.1 ENSG00000203942 Chromosome 10 open reading frame 62 10 97589727-97590934 Predicted intracellular proteins Evidence at protein level HPA072947 Enhanced Not detected Tissue enriched 1082 testis: 244.6 kidney: 0.2 Not detected +SAMD13 ENSG00000203943 Sterile alpha motif domain containing 13 1 84298366-84389957 Predicted intracellular proteins Evidence at protein level HPA058929 Enhanced Approved Mitochondria Glioma:2.06e-8 (favourable) Mixed Tissue enhanced rectum: 25.8;testis: 28.7 colon: 20.7 Mixed +FAM127B CXX1b, DKFZP564B147, MAR8A ENSG00000203950 Family with sequence similarity 127 member B X 135050932-135052196 Predicted intracellular proteins Evidence at protein level Liver cancer:1.10e-5 (unfavourable), Ovarian cancer:2.71e-4 (favourable), Endometrial cancer:2.83e-4 (unfavourable), Cervical cancer:5.35e-4 (favourable) Expressed in all Expressed in all ovary: 24.6 Mixed +CCDC160 ENSG00000203952 Coiled-coil domain containing 160 X 134237047-134246207 Predicted intracellular proteins Evidence at transcript level HPA044684 Uncertain Ovarian cancer:7.62e-6 (favourable), Renal cancer:2.21e-4 (favourable), Endometrial cancer:2.31e-4 (favourable) Mixed Mixed parathyroid gland: 8.4 Cell line enhanced AF22: 29.3;NTERA-2: 4.1;RPTEC TERT1: 6.2 +C1orf141 ENSG00000203963 Chromosome 1 open reading frame 141 1 67092165-67231853 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 13 fallopian tube: 15.5;testis: 28.2 lung: 1.6 Cell line enriched 39 HEL: 13.1 +EFCAB7 KIAA1799, RP4-534K7.1 ENSG00000203965 EF-hand calcium binding domain 7 1 63523372-63572693 Predicted intracellular proteins Evidence at protein level HPA029611, HPA029612, HPA029613 Enhanced Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Glioma:4.84e-4 (favourable) Mixed Mixed testis: 24.7 Expressed in all +DEFB110 DEFB-10, DEFB-11, DEFB111 ENSG00000203970 Defensin beta 110 6 50009138-50021981 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 3627 epididymis: 1094.2 seminal vesicle: 0.3 Not detected +GLYATL3 bA28H17.2, C6orf140 ENSG00000203972 Glycine-N-acyltransferase like 3 6 49499958-49527047 Predicted intracellular proteins Evidence at transcript level HPA044044 Uncertain Tissue enhanced Not detected liver: 0.7 Cell line enriched 74 T-47d: 13.7 +LDLRAD1 ENSG00000203985 Low density lipoprotein receptor class A domain containing 1 1 54007299-54018186 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052489 Enhanced Uncertain Nucleoplasm
Golgi apparatus Endometrial cancer:9.21e-4 (favourable) Tissue enhanced Tissue enriched 22 fallopian tube: 256.4 lung: 11.7 Cell line enhanced CAPAN-2: 2.2;Hep G2: 7.0 +RHOXF2B ENSG00000203989 Rhox homeobox family member 2B X 120070672-120077705 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003314 Supported Not detected Tissue enriched 19 testis: 2.7 ovary,skin,spleen: 0.1 Group enriched 341 HL-60: 168.7;K-562: 191.8;NB-4: 216.8 +ZYG11A ZYG11 ENSG00000203995 Zyg-11 family member A, cell cycle regulator 1 52842511-52894998 Predicted intracellular proteins Evidence at protein level HPA030378, HPA030379 Uncertain Approved Nucleus Tissue enriched Tissue enhanced testis: 7.1;thyroid gland: 4.0 kidney: 3.1 Cell line enhanced hTEC/SVTERT24-B: 10.5;SiHa: 11.4 +LCN8 LCN5 ENSG00000204001 Lipocalin 8 9 136754386-136758543 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enriched 233 epididymis: 102.0 lymph node,thyroid gland: 0.4 Cell line enriched 9 REH: 2.1 +C1orf185 FLJ27485 ENSG00000204006 Chromosome 1 open reading frame 185 1 51102234-51148086 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 243 testis: 43.0 adipose tissue,gallbladder,parathyroid gland: 0.1 Not detected +GLT6D1 GLTDC1 ENSG00000204007 Glycosyltransferase 6 domain containing 1 9 135623656-135639540 Predicted secreted proteins Evidence at transcript level HPA023424 Uncertain Not detected Tissue enriched 42 testis: 8.3 epididymis: 0.1 Not detected +IFIT1B bA149I23.6, IFIT1L ENSG00000204010 Interferon induced protein with tetratricopeptide repeats 1B 10 89378056-89385205 Predicted intracellular proteins Evidence at protein level HPA062924 Approved Not detected Group enriched 97 bone marrow: 15.3;placenta: 4.1 all non-specific tissues: 0.0 Not detected +CT83 CXorf61, FLJ20611, FLJ22913, KK-LC-1 ENSG00000204019 Cancer/testis antigen 83 X 116461682-116463003 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 60 testis: 85.3 salivary gland: 1.4 Cell line enhanced HeLa: 49.1;U-266/70: 77.2;U-266/84: 38.3 +LIPN bA186O14.3, LIPL4 ENSG00000204020 Lipase family member N 10 88761406-88778242 Disease related genes, Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enriched 7 skin: 39.8 appendix: 5.7 Group enriched 7 Daudi: 1.0;HL-60: 3.5 +LIPK bA186O14.2, LIPL2 ENSG00000204021 Lipase family member K 10 88724544-88752786 Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enriched 11 skin: 37.4 breast: 3.2 Cell line enriched 5 SK-BR-3: 1.9 +LIPJ bA425M17.2, LIPL1 ENSG00000204022 Lipase family member J 10 88586753-88606976 Predicted intracellular proteins Evidence at transcript level HPA048594 Uncertain Not detected Tissue enriched 11 testis: 12.3 epididymis,fallopian tube: 1.1 Not detected +TRPC5OS TRPC5-AS1 ENSG00000204025 TRPC5 opposite strand X 111876051-111903990 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 58 testis: 45.5 epididymis: 0.7 Cell line enhanced U-937: 1.0 +LRIT2 AC022389.4, LRRC22 ENSG00000204033 Leucine rich repeat, Ig-like and transmembrane domains 2 10 84220495-84225589 Predicted membrane proteins Evidence at protein level HPA037788 Supported Not detected Group enriched 11 cerebral cortex: 1.0;skin: 3.1 colon,esophagus,small intestine,spleen,testis: 0.1 Not detected +LRRC73 C6orf154, dJ337H4.2 ENSG00000204052 Leucine rich repeat containing 73 6 43506969-43510686 Predicted intracellular proteins Evidence at protein level HPA046698 Enhanced Approved Cytosol Mixed Tissue enhanced fallopian tube: 8.3;testis: 24.7 cerebral cortex: 6.5 Cell line enhanced AN3-CA: 2.9;MCF7: 2.4;T-47d: 3.0 +FOXO6 ENSG00000204060 Forkhead box O6 1 41361922-41383590 Predicted intracellular proteins Evidence at transcript level Endometrial cancer:7.65e-6 (unfavourable) Expressed in all Mixed cerebral cortex: 4.9 Cell line enhanced BEWO: 19.9;SCLC-21H: 31.9;U-2 OS: 11.0 +TCEAL5 WEX4 ENSG00000204065 Transcription elongation factor A like 5 X 103273691-103276872 Predicted intracellular proteins Evidence at protein level HPA045564, HPA058982, HPA072199 Supported Uncertain Nucleoplasm
Cytosol Pancreatic cancer:8.60e-4 (favourable), Endometrial cancer:9.09e-4 (unfavourable) Tissue enhanced Group enriched 7 cerebral cortex: 82.5;testis: 82.5 adrenal gland: 11.9 Group enriched 7 SCLC-21H: 9.3;SH-SY5Y: 25.9 +SYS1 C20orf169, dJ453C12.4 ENSG00000204070 SYS1, golgi trafficking protein 20 45361937-45376798 Predicted membrane proteins Evidence at protein level HPA046716 Approved Liver cancer:4.62e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 51.8 Expressed in all +TCEAL6 WEX2 ENSG00000204071 Transcription elongation factor A like 6 X 102140476-102142970 Predicted intracellular proteins Evidence at protein level HPA045564, HPA058982 Supported Tissue enriched Group enriched 6 adrenal gland: 14.3;cerebral cortex: 63.5;testis: 34.6 endometrium: 5.8 Not detected +INPP5B ENSG00000204084 Inositol polyphosphate-5-phosphatase B 1 37860697-37947057 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028803 Approved Approved Cytosol Renal cancer:6.11e-5 (unfavourable), Head and neck cancer:1.11e-4 (favourable), Pancreatic cancer:5.33e-4 (favourable) Expressed in all Expressed in all ovary: 26.3 Expressed in all +RPA4 HSU24186 ENSG00000204086 Replication protein A4 X 96883908-96885467 Predicted intracellular proteins Evidence at protein level HPA066010 Approved Not detected Tissue enriched 7 testis: 2.1 placenta: 0.2 Not detected +NEU4 ENSG00000204099 Neuraminidase 4 2 241808825-241817413 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037394, HPA037395 Uncertain Group enriched Group enriched 6 bone marrow: 2.4;cerebral cortex: 6.3;colon: 8.3;duodenum: 5.6;liver: 4.1;rectum: 3.7;small intestine: 5.3 fallopian tube,gallbladder: 0.7 Group enriched 20 Hep G2: 26.3;HMC-1: 45.5 +MAFB KRML ENSG00000204103 MAF bZIP transcription factor B 20 40685848-40689240 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005653 Approved Approved Nucleus
Nucleoli
Golgi apparatus
Cytosol Endometrial cancer:5.64e-4 (unfavourable) Expressed in all Tissue enriched 7 parathyroid gland: 689.3 spleen: 102.0 Cell line enhanced HSkMC: 20.7;hTCEpi: 44.3;SCLC-21H: 19.6;SiHa: 16.5;U-138 MG: 16.2;U-2197: 22.6;U-87 MG: 15.7 +TRAF3IP1 DKFZP434F124, IFT54, MIP-T3, MIPT3 ENSG00000204104 TRAF3 interacting protein 1 2 238320441-238400900 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037857, HPA037858 Approved Melanoma:2.19e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 30.9 Mixed +CHIC1 BRX ENSG00000204116 Cysteine rich hydrophobic domain 1 X 73563200-73687102 Predicted membrane proteins Evidence at protein level HPA026782, HPA052062 Uncertain Approved Nuclear speckles
Vesicles
Cytosol Renal cancer:2.75e-4 (favourable) Mixed Mixed cerebral cortex: 14.2 Mixed +NAP1L6 FLJ33596 ENSG00000204118 Nucleosome assembly protein 1 like 6 X 73126037-73128080 Predicted intracellular proteins Evidence at transcript level HPA044957 Uncertain Mixed Mixed thyroid gland: 1.2 Group enriched 6 U-2 OS: 3.4;U-266/84: 2.1 +GIGYF2 GYF2, KIAA0642, PARK11, PERQ2, PERQ3, TNRC15 ENSG00000204120 GRB10 interacting GYF protein 2 2 232697299-232860575 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050899, HPA054612, HPA059918, HPA065064 Approved Enhanced Cytosol Renal cancer:6.97e-5 (favourable) Expressed in all Expressed in all testis: 85.1 Expressed in all +C2orf72 LOC257407 ENSG00000204128 Chromosome 2 open reading frame 72 2 231037490-231049719 Predicted intracellular proteins Evidence at protein level HPA044962 Uncertain Approved Nucleus
Plasma membrane Renal cancer:4.74e-4 (unfavourable), Pancreatic cancer:5.27e-4 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 2.8;colon: 2.9;liver: 4.7 stomach: 1.3 Cell line enhanced BEWO: 8.2;CACO-2: 1.7;EFO-21: 2.9 +RUFY2 FLJ10063, KIAA1537, RABIP4R, ZFYVE13 ENSG00000204130 RUN and FYVE domain containing 2 10 68341107-68407294 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039792 Approved Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 36.8 Expressed in all +NHSL2 ENSG00000204131 NHS like 2 X 71910818-72161750 Predicted intracellular proteins Evidence at protein level HPA049771, HPA054858 Uncertain Mixed Mixed smooth muscle: 10.0 Cell line enhanced AF22: 24.9;EFO-21: 27.8;HUVEC TERT2: 23.1;TIME: 13.2;U-937: 16.2 +PHACTR4 FLJ13171, PPP1R124 ENSG00000204138 Phosphatase and actin regulator 4 1 28369582-28500369 Predicted intracellular proteins Evidence at protein level HPA028985 Approved Approved Plasma membrane
Intermediate filaments
Cytosol Head and neck cancer:1.05e-4 (favourable) Expressed in all Expressed in all esophagus: 35.7 Expressed in all +CLPSL1 C6orf127, dJ510O8.6 ENSG00000204140 Colipase like 1 6 35781017-35793675 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA073155 Enhanced Group enriched Tissue enriched 38 epididymis: 733.4 pancreas: 19.3 Cell line enriched 25 T-47d: 7.9 +ASAH2B ASAH2C, ASAH2L, bA449O16.3, bA98I6.3 ENSG00000204147 N-acylsphingosine amidohydrolase 2B 10 50739318-50816495 Predicted intracellular proteins Evidence at protein level HPA061171 Supported Approved Focal adhesion sites Mixed Mixed duodenum: 19.6 Mixed +AGAP6 bA324H6.1, CTGLF3 ENSG00000204149 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 10 49982190-50010499 Predicted intracellular proteins Evidence at transcript level HPA042490 Uncertain Renal cancer:9.70e-10 (unfavourable), Urothelial cancer:1.83e-7 (favourable), Pancreatic cancer:2.66e-4 (favourable) Expressed in all Expressed in all skin: 21.8 Expressed in all +TIMM23B bA592B15.7 ENSG00000204152 Translocase of inner mitochondrial membrane 23 homolog B 10 49942033-49974850 Predicted membrane proteins Evidence at transcript level Expressed in all Mixed bone marrow: 5.5 Mixed +ZDHHC18 DKFZp667O2416 ENSG00000204160 Zinc finger DHHC-type containing 18 1 26826710-26857602 Enzymes, Predicted membrane proteins Evidence at protein level HPA040234 Approved Approved Microtubules Renal cancer:1.36e-10 (unfavourable), Liver cancer:7.42e-7 (unfavourable), Glioma:9.53e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 75.2 Expressed in all +C10orf128 Em:AC084727.5 ENSG00000204161 Chromosome 10 open reading frame 128 10 49154725-49188585 Predicted membrane proteins Evidence at transcript level HPA058166 Approved Renal cancer:2.86e-5 (unfavourable) Expressed in all Mixed lung: 40.6 Cell line enhanced HDLM-2: 200.6;HEL: 46.6;K-562: 91.3;U-87 MG: 100.7;U-937: 72.4 +CXorf65 ENSG00000204165 Chromosome X open reading frame 65 X 71103889-71106788 Predicted intracellular proteins Evidence at protein level HPA047396 Uncertain Mixed Tissue enriched 10 testis: 19.6 lymph node: 2.0 Cell line enhanced HEL: 1.2;Karpas-707: 2.4;MOLT-4: 1.2;NB-4: 1.3 +AGAP9 bA301J7.2, CTGLF6, FLJ00312 ENSG00000204172 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 10 47501854-47523638 Predicted intracellular proteins Evidence at transcript level HPA042490 Uncertain Renal cancer:3.02e-5 (unfavourable), Colorectal cancer:9.98e-5 (unfavourable), Urothelial cancer:7.04e-4 (favourable) Expressed in all Expressed in all skin: 26.3 Mixed +NPY4R PP1, PPYR1, Y4 ENSG00000204174 Neuropeptide Y receptor Y4 10 46461099-46465881 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA027863 Approved Tissue enhanced Tissue enhanced colon: 5.1;rectum: 6.9 skin: 3.6 Cell line enriched 5 A549: 26.3 +GPRIN2 KIAA0514, MGC15171 ENSG00000204175 G protein regulated inducer of neurite outgrowth 2 10 46549044-46555530 Predicted intracellular proteins Evidence at protein level HPA038129 Approved Approved Nucleoplasm Endometrial cancer:8.60e-8 (unfavourable), Head and neck cancer:3.47e-4 (favourable) Mixed Tissue enhanced lung: 18.0;skin: 18.8 small intestine: 11.7 Group enriched 5 A-431: 12.9;A549: 38.1;SiHa: 8.3;SK-BR-3: 17.1 +SYT15 CHR10SYT ENSG00000204176 Synaptotagmin 15 10 46578217-46594173 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA036971, HPA036972, HPA064559 Uncertain Approved Golgi apparatus Not detected Mixed lung: 21.1 Cell line enhanced SK-BR-3: 23.7 +TMEM57 FLJ10747 ENSG00000204178 Transmembrane protein 57 1 25430858-25500209 Predicted membrane proteins, Transporters Evidence at protein level HPA019680 Approved Cytosol Renal cancer:7.13e-4 (favourable) Expressed in all Expressed in all testis: 36.1 Expressed in all +PTPN20 bA142I17.1, bA42B19.1, CT126, DKFZP566K0524, PTPN20A, PTPN20B ENSG00000204179 Protein tyrosine phosphatase, non-receptor type 20 10 46911396-47002488 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043337, HPA046896, HPA048310 Uncertain Supported Microtubule organizing center Mixed Tissue enhanced testis: 25.3 adrenal gland: 12.2 Cell line enhanced HDLM-2: 46.4;SiHa: 9.6 +GDF5OS ENSG00000204183 Growth differentiation factor 5 opposite strand 20 35433029-35435450 Predicted intracellular proteins Evidence at transcript level HPA062720 Uncertain Not detected Not detected adipose tissue: 0.3 Not detected +ZDBF2 FLJ45338, KIAA1571 ENSG00000204186 Zinc finger DBF-type containing 2 2 206274663-206314428 Predicted intracellular proteins Evidence at protein level HPA039121, HPA050311 Uncertain Enhanced Nucleoplasm
Cytosol Mixed Mixed cerebral cortex: 5.1 Mixed +TXNDC8 bA427L11.2, SPTRX-3, TRX6 ENSG00000204193 Thioredoxin domain containing 8 9 110303521-110337884 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 371 testis: 44.0 kidney,lymph node,seminal vesicle: 0.1 Cell line enhanced THP-1: 1.1 +AWAT1 DGAT2L3 ENSG00000204195 Acyl-CoA wax alcohol acyltransferase 1 X 70234655-70240627 Enzymes, Predicted membrane proteins Evidence at protein level HPA063412 Supported Not detected Not detected breast: 0.8 Not detected +DAXX DAP6 ENSG00000204209 Death domain associated protein 6 33318558-33329286 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB002224, HPA008736, HPA008797, CAB025546, HPA065779 Enhanced Enhanced Nucleus
Nuclear bodies Renal cancer:6.32e-7 (unfavourable), Breast cancer:6.05e-4 (favourable) Expressed in all Mixed epididymis: 19.3 Mixed +BMPR2 BMPR-II, BMPR3, BRK-3, PPH1, T-ALK ENSG00000204217 Bone morphogenetic protein receptor type 2 2 202376936-202567751 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA017385, HPA049014 Approved Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all placenta: 44.9 Mixed +TCEA3 TFIIS.H ENSG00000204219 Transcription elongation factor A3 1 23381061-23424740 Predicted intracellular proteins Evidence at protein level HPA044960, HPA055811 Approved Approved Nucleoplasm
Vesicles Head and neck cancer:2.56e-4 (favourable) Expressed in all Tissue enhanced skeletal muscle: 157.4 ovary: 62.8 Cell line enhanced Hep G2: 43.0;SiHa: 21.8;T-47d: 30.3 +PFDN6 H2-KE2, HKE2, KE-2, PFD6 ENSG00000204220 Prefoldin subunit 6 6 33289302-33298401 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043032, HPA048123 Enhanced Approved Nucleus
Golgi apparatus Ovarian cancer:1.01e-4 (favourable), Renal cancer:8.97e-4 (unfavourable) Expressed in all Expressed in all testis: 20.9 Expressed in all +RING1 RNF1 ENSG00000204227 Ring finger protein 1 6 33208495-33212722 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008701 Supported Approved Nucleoplasm
Cytosol Expressed in all Mixed endometrium: 8.2 Mixed +HSD17B8 D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1 ENSG00000204228 Hydroxysteroid 17-beta dehydrogenase 8 6 33204642-33206831 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042132 Enhanced Renal cancer:2.18e-12 (favourable), Liver cancer:1.90e-5 (favourable), Breast cancer:9.99e-4 (favourable) Expressed in all Mixed parathyroid gland: 9.9 Cell line enhanced RPMI-8226: 11.7;T-47d: 9.9;U-266/70: 12.1 +RXRB H-2RIIBP, NR2B2, RCoR-1 ENSG00000204231 Retinoid X receptor beta 6 33193588-33200688 Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002003, HPA063653 Supported Supported Nucleus Expressed in all Mixed epididymis: 15.7 Cell line enhanced RH-30: 8.5;T-47d: 8.2 +OXLD1 C17orf90, MGC104712 ENSG00000204237 Oxidoreductase like domain containing 1 17 81665036-81666635 Predicted intracellular proteins Evidence at protein level HPA056878, HPA057019 Uncertain Approved Vesicles
Cytosol Cervical cancer:2.91e-4 (favourable) Expressed in all Mixed testis: 10.7 Cell line enhanced A549: 54.5 +OR13C3 ENSG00000204246 Olfactory receptor family 13 subfamily C member 3 9 104535749-104536856 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA053978 Uncertain Not detected Not detected testis: 0.3 Not detected +COL11A2 DFNA13, DFNB53, HKE5 ENSG00000204248 Collagen type XI alpha 2 chain 6 33162681-33192499 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enhanced testis: 1.2 cerebral cortex: 0.7 Not detected +HLA-DOA HLA-D0-alpha, HLA-DNA, HLA-DZA ENSG00000204252 Major histocompatibility complex, class II, DO alpha 6 33004178-33009612 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA045038 Enhanced Expressed in all Tissue enhanced spleen: 14.4 tonsil: 8.9 Cell line enhanced Daudi: 4.6;HDLM-2: 4.3;REH: 19.0;U-698: 3.4 +BRD2 BRD2-IT1, D6S113E, FSRG1, KIAA9001, NAT, RING3 ENSG00000204256 Bromodomain containing 2 6 32968660-32981505 Predicted intracellular proteins Evidence at protein level HPA042816 Approved Enhanced Nuclear speckles Expressed in all Expressed in all thyroid gland: 101.8 Expressed in all +HLA-DMA D6S222E, RING6 ENSG00000204257 Major histocompatibility complex, class II, DM alpha 6 32948613-32969094 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012750, HPA017295 Enhanced Approved Vesicles Endometrial cancer:4.64e-5 (favourable), Lung cancer:4.59e-4 (favourable) Expressed in all Tissue enhanced lung: 65.0 fallopian tube: 41.9 Cell line enhanced U-266/70: 22.0;U-266/84: 9.5;U-698: 52.4 +COL5A2 ENSG00000204262 Collagen type V alpha 2 chain 2 189031896-189179879 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.53e-10 (unfavourable), Urothelial cancer:3.58e-4 (unfavourable), Lung cancer:5.37e-4 (unfavourable) Expressed in all Mixed placenta: 154.0 Cell line enhanced BJ hTERT+ SV40 Large T+: 407.0;BJ hTERT+ SV40 Large T+ RasG12V: 363.2;fHDF/TERT166: 325.7 +PSMB8 beta5i, D6S216E, LMP7, PSMB5i, RING10 ENSG00000204264 Proteasome subunit beta 8 6 32840717-32844703 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046995, HPA050327 Enhanced Approved Vesicles
Cytokinetic bridge Breast cancer:5.08e-4 (favourable), Endometrial cancer:7.16e-4 (favourable) Expressed in all Mixed lymph node: 23.0 Mixed +TAP2 ABCB3, D6S217E, PSF2, RING11 ENSG00000204267 Transporter 2, ATP binding cassette subfamily B member 6 32821833-32838780 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA001312 Approved Approved Nuclear speckles
Endoplasmic reticulum Renal cancer:5.22e-8 (unfavourable), Pancreatic cancer:1.51e-4 (unfavourable) Expressed in all Mixed urinary bladder: 15.1 Cell line enhanced U-251 MG: 53.5 +SPIN3 TDRD27 ENSG00000204271 Spindlin family member 3 X 56818298-56995827 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000727 Uncertain Approved Nucleoplasm Endometrial cancer:3.49e-4 (unfavourable), Urothelial cancer:6.30e-4 (favourable), Lung cancer:6.79e-4 (favourable) Expressed in all Mixed cerebral cortex: 13.2 Mixed +NBDY LINC01420, NoBody ENSG00000204272 Negative regulator of P-body association X 56729241-56818380 Predicted intracellular proteins Evidence at protein level Endometrial cancer:3.14e-5 (unfavourable), Head and neck cancer:3.11e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 71.9 Mixed +TMEM235 ENSG00000204278 Transmembrane protein 235 17 78231310-78240987 Predicted membrane proteins Evidence at transcript level HPA053939 Uncertain Tissue enriched Tissue enriched 100 cerebral cortex: 15.6 placenta,testis: 0.1 Not detected +PAGE3 CT16.6, GAGED1, PAGE-3 ENSG00000204279 PAGE family member 3 X 55258412-55264846 Predicted intracellular proteins Evidence at protein level HPA062248 Uncertain Not detected Tissue enriched 86 testis: 8.5 all non-specific tissues: 0.0 Not detected +HLA-DRA HLA-DRA1 ENSG00000204287 Major histocompatibility complex, class II, DR alpha 6 32439842-32445046 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002798, CAB015402, HPA050162, HPA053176 Enhanced Colorectal cancer:5.30e-4 (favourable) Expressed in all Tissue enhanced lung: 731.8;lymph node: 894.1 tonsil: 476.7 Cell line enhanced Daudi: 254.2;HDLM-2: 588.3;REH: 234.5;U-698: 247.8;U-87 MG: 236.0 +BTNL2 BTL-II, BTN7, HSBLMHC1 ENSG00000204290 Butyrophilin like 2 6 32393963-32407128 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Not detected prostate: 0.2 Not detected +COL15A1 ENSG00000204291 Collagen type XV alpha 1 chain 9 98943179-99070792 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA017913, HPA017915 Enhanced Approved Endoplasmic reticulum Urothelial cancer:3.08e-4 (unfavourable), Liver cancer:5.47e-4 (favourable) Expressed in all Tissue enhanced placenta: 312.1 smooth muscle: 146.2 Cell line enhanced BJ: 21.5;BJ hTERT+: 42.8;HDLM-2: 21.5;U-2197: 40.3;WM-115: 29.2 +OR8B2 ENSG00000204293 Olfactory receptor family 8 subfamily B member 2 11 124382395-124383362 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 26 testis: 2.5 all non-specific tissues: 0.0 Not detected +C6orf10 TSBP ENSG00000204296 Chromosome 6 open reading frame 10 6 32288526-32371912 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enriched 73 testis: 15.6 lymph node: 0.2 Not detected +TMEM225 PMP22CD, PPP1R154 ENSG00000204300 Transmembrane protein 225 11 123882926-123885642 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 398 testis: 39.8 all non-specific tissues: 0.0 Not detected +NOTCH4 INT3 ENSG00000204301 Notch 4 6 32194843-32224067 Predicted membrane proteins Evidence at protein level Renal cancer:3.84e-4 (unfavourable) Expressed in all Tissue enhanced lung: 12.1 thyroid gland: 4.2 Not detected +PBX2 G17, HOX12, PBX2MHC ENSG00000204304 PBX homeobox 2 6 32184741-32190186 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA061478 Enhanced Approved Nucleoplasm Endometrial cancer:8.90e-5 (unfavourable), Ovarian cancer:6.84e-4 (favourable) Expressed in all Expressed in all epididymis: 36.1 Mixed +AGER RAGE, SCARJ1 ENSG00000204305 Advanced glycosylation end-product specific receptor 6 32180968-32184324 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB011682, HPA064436 Enhanced Approved Nucleoli fibrillar center
Plasma membrane
Cell Junctions Renal cancer:9.01e-7 (unfavourable), Urothelial cancer:2.74e-6 (favourable), Pancreatic cancer:3.41e-4 (favourable) Expressed in all Tissue enriched 181 lung: 889.2 thyroid gland: 4.9 Cell line enhanced HEK 293: 2.5;U-266/70: 2.6 +RNF5 G16, NG2, RING5, RMA1 ENSG00000204308 Ring finger protein 5 6 32178354-32180793 Enzymes, Predicted membrane proteins Evidence at protein level CAB034107, HPA065032 Uncertain Supported Endoplasmic reticulum Ovarian cancer:2.44e-4 (favourable) Expressed in all Mixed kidney: 18.6 Mixed +AGPAT1 LPAAT-alpha ENSG00000204310 1-acylglycerol-3-phosphate O-acyltransferase 1 6 32168212-32178096 Enzymes, Predicted membrane proteins Evidence at protein level HPA048478, HPA073355 Approved Supported Endoplasmic reticulum
Rods & Rings Breast cancer:1.93e-4 (unfavourable), Endometrial cancer:5.21e-4 (unfavourable) Expressed in all Mixed epididymis: 52.2 Mixed +DFNB59 pejvakin ENSG00000204311 Deafness, autosomal recessive 59 2 178451436-178461390 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA042621 Supported Mitochondria Renal cancer:8.92e-4 (unfavourable) Mixed Tissue enriched 6 testis: 32.4 ovary: 5.4 Mixed +PRRT1 C6orf31, IFITMD7, NG5 ENSG00000204314 Proline rich transmembrane protein 1 6 32148359-32154373 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055149, HPA059099 Enhanced Mixed Tissue enriched 8 cerebral cortex: 4.5 ovary: 0.6 Cell line enhanced SK-MEL-30: 1.1 +FKBPL DIR1, NG7, WISp39 ENSG00000204315 FK506 binding protein like 6 32128707-32130291 Predicted intracellular proteins Evidence at protein level HPA043478, HPA060158 Enhanced Approved Nucleoplasm Ovarian cancer:8.46e-4 (favourable) Expressed in all Mixed thyroid gland: 5.0 Mixed +MRPL38 HSPC262, MGC4810, MRP-L3, RPML3 ENSG00000204316 Mitochondrial ribosomal protein L38 17 75898643-75905413 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA023054, HPA023135 Approved Supported Mitochondria Urothelial cancer:9.21e-5 (favourable), Pancreatic cancer:4.23e-4 (favourable), Renal cancer:5.58e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 30.7 Expressed in all +SMIM5 C17orf109 ENSG00000204323 Small integral membrane protein 5 17 75633434-75641404 Predicted membrane proteins Evidence at protein level HPA065332, HPA071268 Approved Approved Golgi apparatus
Vesicles Renal cancer:1.12e-4 (favourable), Cervical cancer:5.52e-4 (favourable) Mixed Mixed thyroid gland: 14.3 Cell line enhanced MCF7: 8.0;SK-BR-3: 3.4 +ERICH2 ENSG00000204334 Glutamate rich 2 2 170783786-170798971 Predicted intracellular proteins Evidence at protein level HPA061010 Approved Nucleoli fibrillar center
Vesicles Renal cancer:8.98e-7 (unfavourable), Endometrial cancer:9.49e-4 (favourable) Expressed in all Tissue enriched 8 testis: 233.8 thyroid gland: 30.5 Cell line enhanced hTCEpi: 44.3 +SP5 ENSG00000204335 Sp5 transcription factor 2 170715351-170718078 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA074123 Approved Nucleus
Nucleoli Mixed Tissue enhanced endometrium: 3.9 stomach: 2.3 Group enriched 12 CACO-2: 23.0;Hep G2: 83.0 +STK19 D6S60, G11, RP1 ENSG00000204344 Serine/threonine kinase 19 6 31971091-31982821 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA031510, HPA031511, HPA068559 Uncertain Supported Nuclear speckles Melanoma:1.18e-4 (unfavourable) Expressed in all Mixed testis: 1.2 Cell line enhanced HDLM-2: 1.9;REH: 1.7 +CD300LD CD300D, CMRF35A4 ENSG00000204345 CD300 molecule like family member d 17 74579365-74592283 CD markers, Predicted membrane proteins Evidence at protein level HPA027756 Uncertain Not detected Not detected appendix: 0.9 Not detected +BTBD17 BTBD17A, LGALS3BPL, TANGO10A ENSG00000204347 BTB domain containing 17 17 74356416-74361946 Predicted secreted proteins Evidence at protein level HPA025022 Approved Group enriched Tissue enriched 19 cerebral cortex: 12.9 adrenal gland: 0.6 Group enriched 24 AF22: 2.7;NTERA-2: 3.6;SCLC-21H: 12.8 +DXO DOM3Z ENSG00000204348 Decapping exoribonuclease 6 31969810-31972292 Predicted intracellular proteins Evidence at protein level HPA046708 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:4.77e-6 (unfavourable), Pancreatic cancer:5.87e-4 (favourable) Expressed in all Mixed testis: 5.7 Cell line enhanced AN3-CA: 10.2 +SKIV2L 170A, DDX13, HLP, SKI2W, SKIV2, SKIV2L1 ENSG00000204351 Ski2 like RNA helicase 6 31959080-31969755 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051959, HPA054419 Uncertain Approved Nucleoplasm Renal cancer:3.02e-7 (unfavourable), Liver cancer:6.58e-4 (unfavourable) Expressed in all Mixed epididymis: 10.5 Mixed +C9orf129 bA165J3.3 ENSG00000204352 Chromosome 9 open reading frame 129 9 93318199-93346414 Predicted intracellular proteins Evidence at transcript level HPA071515 Uncertain Mitochondria Not detected Group enriched 7 cerebral cortex: 4.1;testis: 1.7 epididymis: 0.4 Cell line enriched 9 NTERA-2: 2.1 +NELFE D6S45, NELF-E, RD, RDBP, RDP ENSG00000204356 Negative elongation factor complex member E 6 31952087-31959110 Predicted intracellular proteins Evidence at protein level HPA007187, HPA007594, HPA046502 Enhanced Enhanced Nucleoplasm
Nuclear bodies Renal cancer:2.70e-4 (unfavourable) Expressed in all Expressed in all testis: 49.4 Expressed in all +NXPE2 FAM55B, FLJ25224 ENSG00000204361 Neurexophilin and PC-esterase domain family member 2 11 114678386-114706933 Predicted intracellular proteins Evidence at protein level HPA039744, HPA039876 Enhanced Colorectal cancer:9.29e-5 (favourable) Tissue enhanced Tissue enhanced colon: 9.5;epididymis: 30.3;rectum: 9.7 salivary gland: 8.2 Not detected +SPANXN5 CT11.10, SPANX-N5 ENSG00000204363 SPANX family member N5 X 52796144-52798101 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 106 testis: 11.5 placenta: 0.1 Not detected +ZBTB12 C6orf46, D6S59E, G10, NG35 ENSG00000204366 Zinc finger and BTB domain containing 12 6 31899607-31901992 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047161 Approved Renal cancer:1.52e-4 (unfavourable) Expressed in all Mixed endometrium: 1.7 Mixed +SDHD cybS, PGL, PGL1 ENSG00000204370 Succinate dehydrogenase complex subunit D 11 112086773-112120013 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA045727 Approved Renal cancer:1.99e-10 (favourable) Expressed in all Expressed in all kidney: 305.5 Expressed in all +EHMT2 BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a ENSG00000204371 Euchromatic histone lysine methyltransferase 2 6 31879759-31897687 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA050550, HPA060259 Supported Supported Nucleoplasm
Nuclear speckles Liver cancer:1.79e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 4.7 Cell line enhanced NTERA-2: 19.2 +XAGE1A CT12.1a, GAGED2, XAGE-1, XAGE1 ENSG00000204379 X antigen family member 1A X 52495676-52500812 Predicted intracellular proteins Evidence at protein level HPA077164 Uncertain Nuclear speckles Not detected Tissue enriched 186 testis: 65.7 adipose tissue,cervix, uterine,liver,lymph node: 0.3 Cell line enhanced HMC-1: 491.2;NB-4: 361.0;THP-1: 391.2;U-2 OS: 422.6;U-266/84: 543.0;U-937: 364.8 +LAYN FLJ30977, FLJ31092 ENSG00000204381 Layilin 11 111540280-111561745 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040087 Approved Approved Cytosol Expressed in all Mixed ovary: 49.6 Cell line enhanced BJ: 126.5;BJ hTERT+: 131.6;BJ hTERT+ SV40 Large T+ RasG12V: 98.0;U-138 MG: 107.5 +XAGE1B CT12.1b ENSG00000204382 X antigen family member 1B X 52512077-52520803 Predicted intracellular proteins Evidence at protein level HPA077164 Uncertain Nuclear speckles Not detected Tissue enriched 42 testis: 70.1 lung: 1.6 Cell line enhanced HMC-1: 528.0;NB-4: 387.4;THP-1: 397.2;U-2 OS: 451.2;U-266/84: 561.1;U-937: 379.7 +SLC44A4 C6orf29, CTL4, FLJ14491, NG22, TPPT ENSG00000204385 Solute carrier family 44 member 4 6 31863192-31879046 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046977, HPA054176 Enhanced Renal cancer:1.06e-6 (favourable), Head and neck cancer:3.54e-4 (favourable), Urothelial cancer:6.06e-4 (favourable) Tissue enhanced Tissue enhanced duodenum: 35.1 colon: 28.7 Cell line enhanced Hep G2: 1.0 +NEU1 NEU ENSG00000204386 Neuraminidase 1 6 31857659-31862906 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015634, HPA021506 Approved Supported Vesicles
Cell Junctions Expressed in all Mixed thyroid gland: 14.3 Expressed in all +C6orf48 D6S57, G8 ENSG00000204387 Chromosome 6 open reading frame 48 6 31834608-31839766 Predicted intracellular proteins Evidence at transcript level Expressed in all Expressed in all ovary: 110.8 Expressed in all +HSPA1B HSP70-2 ENSG00000204388 Heat shock protein family A (Hsp70) member 1B 6 31827735-31830255 Predicted intracellular proteins Evidence at protein level CAB008640, HPA052504 Approved Approved Nucleoplasm
Vesicles Expressed in all Tissue enhanced adrenal gland: 34.3 parathyroid gland: 14.6 Cell line enhanced A549: 74.8;Karpas-707: 175.2;U-266/70: 30.2 +HSPA1A HSP70-1, HSPA1 ENSG00000204389 Heat shock protein family A (Hsp70) member 1A 6 31815464-31817946 Predicted intracellular proteins Evidence at protein level CAB017451, CAB032815, HPA052504 Supported Approved Nucleoplasm
Vesicles Colorectal cancer:1.54e-5 (unfavourable) Expressed in all Mixed adrenal gland: 49.9 Cell line enriched 10 HEK 293: 3834.6 +HSPA1L HSP70-HOM, hum70t ENSG00000204390 Heat shock protein family A (Hsp70) member 1 like 6 31809619-31815065 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043285, HPA052504 Enhanced Approved Nucleoplasm
Vesicles Ovarian cancer:1.02e-4 (favourable), Renal cancer:4.63e-4 (favourable) Expressed in all Tissue enriched 8 testis: 9.8 epididymis: 1.2 Cell line enhanced HEK 293: 2.3 +LSM2 C6orf28, G7b, YBL026W ENSG00000204392 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated 6 31797396-31806984 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA066718 Supported Supported Nucleus Renal cancer:5.59e-9 (unfavourable) Expressed in all Mixed fallopian tube: 7.1 Expressed in all +VARS VARS2 ENSG00000204394 Valyl-tRNA synthetase 6 31777518-31795953 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046710 Approved Enhanced Cytosol Liver cancer:1.86e-4 (unfavourable), Lung cancer:6.90e-4 (unfavourable), Cervical cancer:7.25e-4 (unfavourable) Expressed in all Mixed testis: 5.5 Mixed +VWA7 C6orf27, G7c, NG37 ENSG00000204396 Von Willebrand factor A domain containing 7 6 31765590-31777294 Predicted secreted proteins Evidence at transcript level HPA046954, HPA054262 Approved Approved Plasma membrane
Cytosol Renal cancer:4.35e-8 (favourable) Mixed Tissue enhanced fallopian tube: 9.1 parathyroid gland: 1.9 Cell line enhanced U-266/70: 1.0 +CARD16 COP, COP1, PSEUDO-ICE ENSG00000204397 Caspase recruitment domain family member 16 11 105041326-105101431 Predicted intracellular proteins Evidence at protein level HPA053981, HPA062805 Uncertain Uncertain Mitochondria Renal cancer:6.93e-7 (unfavourable) Expressed in all Expressed in all spleen: 159.0 Cell line enhanced AN3-CA: 139.1;HHSteC: 214.1;HUVEC TERT2: 101.4;TIME: 91.2 +MBD5 FLJ11113, KIAA1461 ENSG00000204406 Methyl-CpG binding domain protein 5 2 148021011-148516971 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035964 Supported Nucleus
Midbody Endometrial cancer:3.72e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 15.3 Mixed +MSH5 G7 ENSG00000204410 MutS homolog 5 6 31739948-31762834 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA062688 Approved Endoplasmic reticulum
Vesicles Mixed Mixed skin: 1.7 Mixed +CSHL1 CS-5, CSHP1, CSL, hCS-L, MGC149868 ENSG00000204414 Chorionic somatomammotropin hormone like 1 17 63909597-63918838 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025646, HPA043715 Enhanced Not detected Tissue enriched 352 placenta: 216.7 smooth muscle: 0.6 Not detected +MPIG6B C6orf25, G6b, G6b-B, NG31 ENSG00000204420 Megakaryocyte and platelet inhibitory receptor G6b 6 31718594-31726714 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA073017 Uncertain Golgi apparatus Mixed Not detected skin: 0.8 Cell line enriched 16 HEL: 5.4 +LY6G6C C6orf24, G6c, NG24 ENSG00000204421 Lymphocyte antigen 6 family member G6C 6 31718648-31721845 Predicted membrane proteins Evidence at protein level Mixed Tissue enriched 8 skin: 64.3 esophagus: 7.5 Not detected +XXbac-BPG32J3.20 ENSG00000204422 6 31686962-31714072 Predicted secreted proteins Evidence at transcript level Not detected Not detected thyroid gland: 0.9 Cell line enriched 29 HEL: 4.7 +LY6G6F C6orf21, G6f, LY6G6D, NG32 ENSG00000204424 Lymphocyte antigen 6 family member G6F 6 31706885-31710595 Predicted membrane proteins Evidence at protein level HPA008053 Uncertain Not detected Not detected bone marrow: 0.4 Cell line enriched 79 HEL: 7.9 +ABHD16A BAT5, D6S82E, NG26 ENSG00000204427 Abhydrolase domain containing 16A 6 31686949-31703444 Predicted membrane proteins Evidence at protein level HPA058606 Approved Endometrial cancer:2.63e-4 (unfavourable) Expressed in all Tissue enhanced gallbladder: 1.7;testis: 1.2;thyroid gland: 1.4 esophagus: 0.9 Not detected +LY6G5C C6orf20, G5c, NG33 ENSG00000204428 Lymphocyte antigen 6 family member G5C 6 31676684-31684040 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038690 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:1.07e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 1.5 testis: 0.9 Not detected +CSNK2B ENSG00000204435 Casein kinase 2 beta 6 31665236-31670343 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004349, HPA005944, CAB013087, CAB016059 Approved Renal cancer:1.06e-5 (unfavourable) Expressed in all Mixed epididymis: 55.3 Mixed +GPANK1 ANKRD59, BAT4, D6S54E, G5, GPATCH10 ENSG00000204438 G-patch domain and ankyrin repeats 1 6 31661229-31666283 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006301 Approved Approved Endoplasmic reticulum Pancreatic cancer:5.89e-4 (favourable) Expressed in all Mixed testis: 9.7 Mixed +C6orf47 D6S53E, G4 ENSG00000204439 Chromosome 6 open reading frame 47 6 31658298-31660772 Predicted membrane proteins Evidence at protein level HPA045281, HPA053373 Uncertain Approved Cytosol Expressed in all Mixed skin: 5.4 Cell line enhanced HBEC3-KT: 5.6;HEK 293: 5.9;RT4: 5.8;U-2 OS: 5.7 +FAM155A ENSG00000204442 Family with sequence similarity 155 member A 13 107163510-107866735 Predicted membrane proteins Evidence at protein level HPA039453, HPA058768 Enhanced Approved Nucleus
Vesicles
Centrosome Mixed Tissue enriched 6 cerebral cortex: 15.6 seminal vesicle: 2.4 Cell line enhanced RPTEC TERT1: 9.3;SCLC-21H: 8.9;SH-SY5Y: 18.1;U-87 MG: 10.5 +APOM ApoM, G3a, NG20 ENSG00000204444 Apolipoprotein M 6 31652416-31658210 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB034086, HPA051006 Approved Approved Golgi apparatus Tissue enriched Mixed testis: 5.6 Mixed +TRIM49C TRIM49L2 ENSG00000204449 Tripartite motif containing 49C 11 90031106-90042025 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.2 Not detected +TRIM64 C11orf28, TRIM64A ENSG00000204450 Tripartite motif containing 64 11 89968502-89975228 Predicted intracellular proteins Evidence at transcript level HPA045370 Approved Not detected Tissue enriched 11 placenta: 1.1 all non-specific tissues: 0.0 Not detected +BAG6 BAT3, D6S52E, G3 ENSG00000204463 BCL2 associated athanogene 6 6 31639028-31652705 Predicted intracellular proteins Evidence at protein level CAB020704, HPA045116, HPA053291 Enhanced Enhanced Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 135.9 Expressed in all +PRRC2A BAT2, D6S51E, G2 ENSG00000204469 Proline rich coiled-coil 2A 6 31620720-31637771 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB026383, HPA046791, HPA066501 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Mixed testis: 20.7 Cell line enhanced HBEC3-KT: 58.8;HEK 293: 135.9;U-266/70: 57.4;U-266/84: 59.9;U-698: 54.2 +AIF1 AIF-1, Em:AF129756.17, IBA1, IRT-1 ENSG00000204472 Allograft inflammatory factor 1 6 31615184-31617021 Predicted intracellular proteins Evidence at protein level HPA049234, HPA062949 Enhanced Approved Cytosol Renal cancer:2.30e-5 (unfavourable) Expressed in all Tissue enhanced spleen: 78.3 appendix: 50.3 Cell line enhanced HEL: 79.8;HMC-1: 107.9;NB-4: 129.5;THP-1: 46.4 +NCR3 1C7, CD337, LY117, NKp30 ENSG00000204475 Natural cytotoxicity triggering receptor 3 6 31588895-31592985 CD markers, Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced lymph node: 1.7;spleen: 1.5;tonsil: 1.1 appendix: 1.0 Cell line enhanced NB-4: 2.6 +PRAMEF20 OTTHUMT00000008157, PRAMEF21 ENSG00000204478 PRAME family member 20 1 13410450-13421328 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.2 Not detected +PRAMEF17 ENSG00000204479 PRAME family member 17 1 13389632-13392629 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +PRAMEF19 ENSG00000204480 PRAME family member 19 1 13369067-13371693 Predicted intracellular proteins No evidence HPA057423 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +PRAMEF14 ENSG00000204481 PRAME family member 14 1 13342034-13347134 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +LST1 B144, D6S49E, LST-1 ENSG00000204482 Leukocyte specific transcript 1 6 31586124-31588909 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Renal cancer:5.97e-5 (unfavourable), Testis cancer:7.62e-4 (unfavourable), Cervical cancer:7.89e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 68.7;spleen: 48.9 appendix: 32.1 Cell line enhanced HMC-1: 64.7;NB-4: 50.8;THP-1: 128.8;U-937: 79.6 +NFKBIL1 IKBL, NFKBIL ENSG00000204498 NFKB inhibitor like 1 6 31546870-31558829 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Endometrial cancer:3.38e-4 (unfavourable) Expressed in all Mixed fallopian tube: 4.2 Cell line enhanced HEK 293: 22.4;U-266/70: 8.2;U-266/84: 6.7 +PRAMEF15 ENSG00000204501 PRAME family member 15 1 13315581-13322598 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +PRAMEF9 ENSG00000204505 PRAME family member 9 1 13172455-13179464 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +PRAMEF7 ENSG00000204510 PRAME family member 7 1 12916610-12920482 Predicted intracellular proteins Evidence at transcript level HPA049887, HPA051704 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +MCCD1 ENSG00000204511 Mitochondrial coiled-coil domain 1 6 31528717-31530232 Predicted secreted proteins Evidence at transcript level HPA046948 Uncertain Renal cancer:1.73e-4 (favourable) Tissue enhanced Tissue enriched 36 kidney: 3.5 all non-specific tissues: 0.0 Not detected +ZNF814 ENSG00000204514 Zinc finger protein 814 19 57848731-57889074 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043800, HPA053762, HPA072145 Approved Uncertain Nucleus Mixed Mixed thyroid gland: 18.2 Cell line enhanced NTERA-2: 34.7 +MICB PERB11.2 ENSG00000204516 MHC class I polypeptide-related sequence B 6 31494881-31511124 Disease related genes, Predicted membrane proteins Evidence at protein level HPA064618 Approved Golgi apparatus
Vesicles Renal cancer:4.94e-9 (unfavourable), Liver cancer:7.04e-5 (unfavourable) Mixed Tissue enhanced lymph node: 3.2 spleen: 2.8 Cell line enhanced U-266/84: 26.2 +AADACL4 ENSG00000204518 Arylacetamide deacetylase like 4 1 12644547-12667086 Predicted membrane proteins Evidence at protein level HPA043588 Uncertain Not detected Not detected epididymis: 0.7 Not detected +ZNF551 DKFZp686H1038 ENSG00000204519 Zinc finger protein 551 19 57681969-57717301 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038187 Approved Nucleoplasm
Nuclear speckles Melanoma:7.68e-5 (unfavourable), Renal cancer:1.32e-4 (favourable) Expressed in all Mixed testis: 8.0 Mixed +MICA PERB11.1 ENSG00000204520 MHC class I polypeptide-related sequence A 6 31399784-31415315 Predicted membrane proteins Evidence at protein level Cervical cancer:5.88e-4 (unfavourable) Expressed in all Mixed lung: 11.2 Cell line enhanced A-431: 36.1;HAP1: 29.8;HSkMC: 44.2;RPTEC TERT1: 30.9 +ZNF805 ENSG00000204524 Zinc finger protein 805 19 57240685-57255135 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA057665, HPA058895 Uncertain Mixed Mixed parathyroid gland: 5.1 Mixed +HLA-C D6S204, HLA-JY3, PSORS1 ENSG00000204525 Major histocompatibility complex, class I, C 6 31268749-31272130 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Expressed in all Tissue enhanced lung: 744.7 small intestine: 396.9 Cell line enhanced A-431: 660.6;EFO-21: 748.1;RPTEC TERT1: 346.0;U-266/70: 367.3;U-266/84: 281.2 +POU5F1 MGC22487, OCT3, Oct4, OTF3 ENSG00000204531 POU class 5 homeobox 1 6 31164337-31180731 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB025600, CAB026380, HPA058267 Approved Supported Nucleoplasm
Cytosol Urothelial cancer:2.04e-5 (favourable) Tissue enriched Mixed fallopian tube: 6.4 Group enriched 12 HAP1: 366.6;NTERA-2: 938.2 +ZSCAN5C ZNF495C, ZSCAN5CP ENSG00000204532 Zinc finger and SCAN domain containing 5C 19 56202301-56209452 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041263, HPA043123, HPA046836, HPA060667 Uncertain Uncertain Nuclear speckles Not detected Not detected testis: 0.1 Not detected +CCHCR1 C6orf18, HCR ENSG00000204536 Coiled-coil alpha-helical rod protein 1 6 31142439-31158238 Predicted intracellular proteins Evidence at protein level HPA054167 Supported Cytosol Expressed in all Tissue enriched 6 testis: 86.6 fallopian tube: 13.8 Mixed +PSORS1C2 C6orf17, SPR1 ENSG00000204538 Psoriasis susceptibility 1 candidate 2 6 31137536-31139350 Predicted secreted proteins Evidence at protein level HPA061228 Enhanced Tissue enhanced Tissue enriched 65 skin: 24.0 testis: 0.3 Not detected +CDSN D6S586E ENSG00000204539 Corneodesmosin 6 31115090-31120446 Predicted secreted proteins Evidence at protein level HPA044730, HPA054184 Enhanced Group enriched Tissue enriched 20 skin: 77.0 epididymis: 3.7 Cell line enriched 7 A-431: 1.4 +PSORS1C1 C6orf16, SEEK1 ENSG00000204540 Psoriasis susceptibility 1 candidate 1 6 31114750-31140092 Predicted intracellular proteins Evidence at transcript level HPA045049 Uncertain Nucleus Mixed Tissue enriched 9 testis: 27.3 epididymis: 3.0 Cell line enhanced hTCEpi: 1.1 +C6orf15 STG ENSG00000204542 Chromosome 6 open reading frame 15 6 31111223-31112559 Predicted secreted proteins Evidence at transcript level HPA001436 Uncertain Mixed Tissue enhanced cervix, uterine: 2.0 tonsil: 0.8 Group enriched 12 RH-30: 3.1;U-2 OS: 1.4 +MUC21 bCX31G15.2, C6orf205 ENSG00000204544 Mucin 21, cell surface associated 6 30983718-30989903 Predicted membrane proteins Evidence at protein level HPA052028 Enhanced Group enriched Tissue enriched 49 esophagus: 596.4 tonsil: 12.2 Not detected +DEFB121 DEFB-21 ENSG00000204548 Defensin beta 121 20 31404845-31412838 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 6458 epididymis: 2005.4 testis: 0.3 Cell line enriched 19 NB-4: 1.8 +DHX16 DBP2, DDX16, Prp2, PRPF2 ENSG00000204560 DEAH-box helicase 16 6 30653119-30673037 Enzymes, Predicted intracellular proteins Evidence at protein level HPA051455 Enhanced Supported Nucleoplasm Expressed in all Mixed testis: 11.5 Expressed in all +C6orf136 Em:AB023049.8 ENSG00000204564 Chromosome 6 open reading frame 136 6 30647039-30653210 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046804 Uncertain Renal cancer:9.16e-8 (favourable), Urothelial cancer:7.51e-4 (favourable) Expressed in all Mixed parathyroid gland: 8.0 Mixed +MRPS18B C6orf14, HSPC183, MRPS18-2, PTD017 ENSG00000204568 Mitochondrial ribosomal protein S18B 6 30617709-30626395 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043485, HPA050334 Supported Supported Cell Junctions
Mitochondria Renal cancer:3.99e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 13.3 Expressed in all +PPP1R10 CAT53, FB19, p99, PNUTS ENSG00000204569 Protein phosphatase 1 regulatory subunit 10 6 30600400-30618612 Predicted intracellular proteins Evidence at protein level CAB025501, HPA047248, HPA056756 Enhanced Enhanced Nucleoplasm
Nuclear bodies Pancreatic cancer:9.74e-5 (favourable), Cervical cancer:4.84e-4 (favourable) Expressed in all Mixed parathyroid gland: 10.5 Expressed in all +KRTAP5-11 KRTAP5-6, KRTAP5.11 ENSG00000204571 Keratin associated protein 5-11 11 71579714-71603353 Predicted intracellular proteins Evidence at protein level Not detected Not detected duodenum: 0.1 Not detected +KRTAP5-10 KRTAP5.10 ENSG00000204572 Keratin associated protein 5-10 11 71565563-71566738 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced epididymis: 1.7 fallopian tube,seminal vesicle,testis: 0.4 Cell line enriched 9 RT4: 2.8 +ABCF1 ABC50, EST123147 ENSG00000204574 ATP binding cassette subfamily F member 1 6 30571376-30597179 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017578 Approved Enhanced Cytosol Liver cancer:9.47e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 11.3 Expressed in all +PRR3 CAT56, Em:AB014077.1, Em:AB023052.2 ENSG00000204576 Proline rich 3 6 30556886-30563723 Predicted intracellular proteins Evidence at protein level HPA064061 Approved Nucleoplasm
Cytosol Renal cancer:7.84e-7 (unfavourable), Ovarian cancer:6.49e-6 (favourable), Pancreatic cancer:5.61e-5 (favourable) Expressed in all Mixed epididymis: 1.6 Cell line enhanced AN3-CA: 9.7;HAP1: 13.6 +LILRB3 CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB ENSG00000204577 Leukocyte immunoglobulin like receptor B3 19 54216278-54223506 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Mixed Group enriched 5 adipose tissue: 5.4;appendix: 11.3;bone marrow: 9.9;lung: 9.2;spleen: 11.1;urinary bladder: 6.8 placenta: 1.7 Not detected +DDR1 CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6 ENSG00000204580 Discoidin domain receptor tyrosine kinase 1 6 30876421-30900156 CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB010162, CAB025656, HPA057194 Approved Approved Nucleoplasm
Cell Junctions Renal cancer:3.31e-10 (favourable) Expressed in all Mixed cerebral cortex: 51.6 Cell line enhanced HaCaT: 80.3;RT4: 74.6;T-47d: 96.8 +LRCOL1 ENSG00000204583 Leucine rich colipase like 1 12 132603150-132610543 Predicted secreted proteins Evidence at transcript level Liver cancer:7.04e-4 (favourable) Tissue enhanced Tissue enriched 62 epididymis: 54.5 lung: 0.8 Not detected +GNL1 HSR1 ENSG00000204590 G protein nucleolar 1 (putative) 6 30541377-30557174 Predicted intracellular proteins Evidence at protein level CAB033575, HPA043338, HPA050455 Uncertain Supported Vesicles Expressed in all Mixed parathyroid gland: 18.8 Mixed +HLA-E ENSG00000204592 Major histocompatibility complex, class I, E 6 30489467-30494205 Predicted membrane proteins Evidence at protein level CAB024589, HPA031454 Enhanced Approved Vesicles Renal cancer:3.86e-4 (unfavourable) Expressed in all Mixed skin: 153.4 Cell line enhanced U-266/70: 73.1 +DPRX ENSG00000204595 Divergent-paired related homeobox 19 53632056-53637009 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA043682 Uncertain Tissue enriched Tissue enhanced placenta: 1.8 epididymis,testis: 0.5 Not detected +TRIM39 RNF23 ENSG00000204599 Tripartite motif containing 39 6 30326479-30343729 Enzymes, Predicted intracellular proteins Evidence at protein level HPA051120, HPA059496 Uncertain Supported Cytosol Pancreatic cancer:2.50e-4 (favourable) Expressed in all Mixed testis: 4.1 Mixed +ZNF468 ENSG00000204604 Zinc finger protein 468 19 52838008-52857649 Predicted intracellular proteins, Transcription factors Evidence at transcript level Renal cancer:3.94e-7 (favourable), Breast cancer:6.87e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 20.4 Mixed +TRIM15 RNF93, ZNF178, ZNFB7 ENSG00000204610 Tripartite motif containing 15 6 30163206-30172696 Predicted intracellular proteins Evidence at protein level HPA047527 Uncertain Tissue enhanced Tissue enhanced colon: 2.6;duodenum: 3.6 appendix,small intestine: 1.1 Cell line enriched 24 HEL: 15.2 +ZNF616 MGC45556 ENSG00000204611 Zinc finger protein 616 19 52113091-52139922 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062639, HPA071539 Approved Approved Centrosome Expressed in all Expressed in all adrenal gland: 17.2 Mixed +FOXB2 bA159H20.4 ENSG00000204612 Forkhead box B2 9 77019655-77020953 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA067947 Uncertain Tissue enhanced Not detected all non-specific tissues: 0.0 Cell line enriched 10 NTERA-2: 1.3 +TRIM10 HERF1, RFB30, RNF9 ENSG00000204613 Tripartite motif containing 10 6 30151945-30160934 Predicted intracellular proteins Evidence at protein level HPA043325 Uncertain Mixed Not detected kidney: 0.4 Not detected +TRIM40 RNF35 ENSG00000204614 Tripartite motif containing 40 6 30136108-30148735 Predicted intracellular proteins Evidence at protein level HPA043818 Uncertain Tissue enhanced Not detected colon: 0.4 Cell line enriched 11 HEL: 1.0 +TRIM31 C6orf13, HCG1, HCGI, RNF ENSG00000204616 Tripartite motif containing 31 6 30102897-30113106 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046400 Uncertain Group enriched Group enriched 6 colon: 10.0;small intestine: 2.3;stomach: 2.1;urinary bladder: 2.7 duodenum: 0.7 Cell line enriched 527 RT4: 232.7 +RNF39 HZFw1, LIRF ENSG00000204618 Ring finger protein 39 6 30070266-30075887 Predicted intracellular proteins Evidence at protein level CAB019278, HPA047115 Uncertain Uncertain Vesicles
Plasma membrane
Centrosome Mixed Tissue enhanced skin: 3.5 breast: 2.0 Cell line enhanced A-431: 1.1;U-266/84: 2.5 +PPP1R11 CFAP255, HCG-V, HCGV, TCTE5, Tctex5 ENSG00000204619 Protein phosphatase 1 regulatory inhibitor subunit 11 6 30066709-30070333 Predicted intracellular proteins Evidence at protein level HPA043266, HPA060174 Approved Approved Vesicles Expressed in all Tissue enhanced epididymis: 38.2 fallopian tube: 17.0 Cell line enhanced A-431: 42.0;AN3-CA: 57.2;HEL: 34.3;RPTEC TERT1: 32.3;U-266/84: 30.5 +DISP3 KIAA1337, PTCHD2 ENSG00000204624 Dispatched RND transporter family member 3 1 11479166-11537584 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA054579 Uncertain Uncertain Nucleoplasm
Cytosol Tissue enhanced Group enriched 14 cerebral cortex: 8.6;testis: 4.3 adrenal gland,prostate: 0.4 Cell line enhanced AF22: 4.8;NTERA-2: 2.1;SCLC-21H: 2.3;SH-SY5Y: 7.2 +RACK1 Gnb2-rs1, GNB2L1, H12.3 ENSG00000204628 Receptor for activated C kinase 1 5 181236909-181248096 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level CAB004288, HPA021676 Uncertain Enhanced Nucleoplasm
Cytosol Liver cancer:2.98e-6 (unfavourable) Expressed in all Expressed in all ovary: 2103.5 Expressed in all +HLA-G ENSG00000204632 Major histocompatibility complex, class I, G 6 29826967-29831125 Cancer-related genes, Predicted membrane proteins Evidence at protein level CAB016158 Enhanced Melanoma:3.91e-5 (favourable) Expressed in all Tissue enriched 23 placenta: 14.9 duodenum,testis: 0.6 Not detected +TBC1D8 AD3, GRAMD8, HBLP1, VRP ENSG00000204634 TBC1 domain family member 8 2 101007617-101252866 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB015211, HPA037496 Uncertain Supported Nucleus Colorectal cancer:6.73e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 45.1 Cell line enhanced ASC diff: 59.6 +NMS ENSG00000204640 Neuromedin S 2 100470482-100483280 Predicted secreted proteins Evidence at transcript level Not detected Not detected testis: 0.6 Group enriched 7 HL-60: 6.6;HMC-1: 4.2 +HLA-F ENSG00000204642 Major histocompatibility complex, class I, F 6 29722775-29738528 Plasma proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.67e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 41.2 stomach: 28.7 Group enriched 7 A-431: 31.2;HEK 293: 11.2;HEL: 7.8;HHSteC: 8.5;U-266/70: 6.4;U-937: 10.5 +ZFP57 bA145L22, bA145L22.2, C6orf40, ZNF698 ENSG00000204644 ZFP57 zinc finger protein 6 29672392-29681110 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047172 Uncertain Pancreatic cancer:1.95e-4 (favourable) Tissue enriched Not detected cerebral cortex,heart muscle: 0.4 Cell line enriched 25 BEWO: 6.2 +ASPDH ENSG00000204653 Aspartate dehydrogenase domain containing 19 50511600-50514690 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042631, HPA042654 Approved Tissue enriched Tissue enhanced cerebral cortex: 17.9;kidney: 27.9;liver: 34.6 duodenum: 6.9 Cell line enhanced HEK 293: 12.4;MOLT-4: 13.3;SH-SY5Y: 9.8 +MOG BTN6, BTNL11 ENSG00000204655 Myelin oligodendrocyte glycoprotein 6 29656981-29672372 Disease related genes, Predicted membrane proteins Evidence at protein level HPA021873 Enhanced Tissue enriched Not detected cerebral cortex: 0.8 Not detected +OR2H2 hs6M1-12 ENSG00000204657 Olfactory receptor family 2 subfamily H member 2 6 29587455-29589038 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +CBY3 ENSG00000204659 Chibby family member 3 5 179678583-179680974 Predicted intracellular proteins Evidence at transcript level HPA069037 Uncertain Mixed Tissue enriched 5 testis: 2.1 cerebral cortex,skin: 0.4 Cell line enhanced HDLM-2: 1.6 +C9orf57 ENSG00000204669 Chromosome 9 open reading frame 57 9 72051376-72072721 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 224 testis: 26.0 parathyroid gland: 0.1 Not detected +IL31 IL-31 ENSG00000204671 Interleukin 31 12 122172030-122174199 Predicted secreted proteins Evidence at transcript level CAB025657 Approved Not detected Not detected testis: 0.2 Not detected +AKT1S1 Lobe, MGC2865, PRAS40 ENSG00000204673 AKT1 substrate 1 19 49869033-49878459 Predicted intracellular proteins Evidence at protein level CAB021903, HPA043590, HPA064427 Uncertain Supported Cytosol Renal cancer:7.34e-6 (unfavourable), Liver cancer:3.70e-4 (unfavourable), Pancreatic cancer:6.60e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 33.9 Expressed in all +FAM153C NY-REN-7-like ENSG00000204677 Family with sequence similarity 153 member C 5 178006405-178055559 Predicted intracellular proteins Evidence at protein level HPA042585, HPA046691, HPA052337 Uncertain Tissue enhanced Tissue enriched 5 testis: 42.0 cerebral cortex: 8.1 Cell line enhanced U-2 OS: 1.2 +GABBR1 GPRC3A, hGB1a ENSG00000204681 Gamma-aminobutyric acid type B receptor subunit 1 6 29555629-29633976 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA050483, HPA058459 Uncertain Approved Centrosome Renal cancer:3.77e-10 (unfavourable), Pancreatic cancer:2.54e-5 (favourable) Expressed in all Tissue enhanced cerebral cortex: 20.8 spleen: 13.1 Cell line enhanced U-2 OS: 6.7 +CASC10 bA418C1.3, C10orf114 ENSG00000204682 Cancer susceptibility 10 10 21492658-21497262 Predicted intracellular proteins Evidence at transcript level HPA064131 Uncertain Approved Nucleoplasm Glioma:5.81e-4 (unfavourable), Urothelial cancer:5.86e-4 (unfavourable) Mixed Mixed placenta: 4.0 Cell line enhanced AF22: 11.6;AN3-CA: 15.3;BEWO: 15.2 +C10orf113 bA165O3.1 ENSG00000204683 Chromosome 10 open reading frame 113 10 21125763-21146559 Predicted intracellular proteins Evidence at transcript level HPA037013 Uncertain Not detected Tissue enriched 13 testis: 1.7 gallbladder,salivary gland: 0.1 Not detected +MAS1L dJ994E9.2, MAS-L, MRG ENSG00000204687 MAS1 proto-oncogene like, G protein-coupled receptor 6 29486697-29487956 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA017983 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Not detected Tissue enhanced cervix, uterine: 5.1 epididymis: 2.3 Not detected +OR2H1 OR2H6, OR2H8, OR6-2 ENSG00000204688 Olfactory receptor family 2 subfamily H member 1 6 29457181-29464328 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.9 Not detected +OR11A1 hs6M1-18, OR11A2 ENSG00000204694 Olfactory receptor family 11 subfamily A member 1 6 29425504-29457071 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR14J1 hs6M1-28, OR5U1 ENSG00000204695 Olfactory receptor family 14 subfamily J member 1 6 29306690-29307655 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA045575 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR2J2 dJ80I19.4, hs6M1-6, OR6-8 ENSG00000204700 Olfactory receptor family 2 subfamily J member 2 6 29173303-29174574 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR2J3 OR6-6 ENSG00000204701 Olfactory receptor family 2 subfamily J member 3 6 29111891-29112826 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected testis: 0.1 Not detected +OR2B3 OR2B3P, OR6-4 ENSG00000204703 Olfactory receptor family 2 subfamily B member 3 6 29086208-29087313 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR2W1 hs6M1-15 ENSG00000204704 Olfactory receptor family 2 subfamily W member 1 6 29044213-29045240 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +SPDYC Ringo2 ENSG00000204710 Speedy/RINGO cell cycle regulator family member C 11 65170154-65173244 Predicted intracellular proteins Evidence at protein level HPA039891 Uncertain Breast cancer:1.20e-5 (unfavourable) Tissue enhanced Tissue enhanced liver: 1.4;testis: 1.5 epididymis: 0.4 Cell line enhanced BEWO: 6.0;HEL: 6.3;K-562: 15.4 +C9orf135 ENSG00000204711 Chromosome 9 open reading frame 135 9 69820793-69906232 Predicted intracellular proteins Evidence at protein level HPA021261, HPA021325 Uncertain Tissue enriched Group enriched 8 fallopian tube: 55.2;testis: 24.3 parathyroid gland: 5.1 Group enriched 9 HAP1: 11.5;NTERA-2: 29.5 +TRIM27 RFP, RNF76 ENSG00000204713 Tripartite motif containing 27 6 28903002-28923989 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048684, HPA053408 Approved Approved Nucleus
Nucleoli Renal cancer:3.50e-6 (unfavourable), Urothelial cancer:2.71e-4 (favourable) Expressed in all Mixed appendix: 5.6 Mixed +MALRD1 bA265G8.2, C10orf112, Diet1 ENSG00000204740 MAM and LDL receptor class A domain containing 1 10 19048771-19790401 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035732, HPA038106, HPA046848 Uncertain Enhanced Golgi apparatus Tissue enhanced Group enriched 8 duodenum: 30.8;small intestine: 34.4 testis: 3.9 Cell line enriched 9 Karpas-707: 31.8 +RANBP17 ENSG00000204764 RAN binding protein 17 5 170861870-171300015 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA029568, HPA029569 Uncertain Approved Nuclear membrane
Nuclear bodies
Cytosol Mixed Mixed testis: 2.2 Mixed +FAM196B C5orf57 ENSG00000204767 Family with sequence similarity 196 member B 5 169864264-169980740 Predicted intracellular proteins Evidence at transcript level HPA047227 Uncertain Mixed Tissue enhanced breast: 7.6;cerebral cortex: 7.0 ovary: 2.1 Cell line enhanced fHDF/TERT166: 30.1;HUVEC TERT2: 20.4;U-138 MG: 61.2 +FOXD4L5 bA15J10.2 ENSG00000204779 Forkhead box D4-like 5 9 65282101-65285209 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA012836 Uncertain Approved Nucleus Not detected Not detected cerebral cortex: 0.6 Mixed +TTC25 DKFZP434H0115 ENSG00000204815 Tetratricopeptide repeat domain 25 17 41930635-41965651 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023908 Enhanced Mixed Group enriched 8 fallopian tube: 47.3;testis: 70.5 parathyroid gland: 7.4 Cell line enhanced SCLC-21H: 4.9;U-87 MG: 4.8 +MRPL53 ENSG00000204822 Mitochondrial ribosomal protein L53 2 74471958-74473322 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA056185 Uncertain Approved Nucleoli Renal cancer:1.16e-8 (unfavourable), Liver cancer:7.36e-5 (unfavourable), Pancreatic cancer:1.37e-4 (favourable) Expressed in all Expressed in all lymph node: 24.6 Expressed in all +MROH6 C8orf73 ENSG00000204839 Maestro heat like repeat family member 6 8 143566187-143572971 Predicted intracellular proteins Evidence at protein level HPA068049 Uncertain Approved Nucleus Expressed in all Mixed bone marrow: 4.0 Cell line enhanced A-431: 14.0;HaCaT: 11.7;SK-BR-3: 20.9;U-937: 12.8 +ATXN2 ATX2, SCA2, TNRC13 ENSG00000204842 Ataxin 2 12 111452214-111599676 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018295, HPA020339, HPA021146 Enhanced Enhanced Cytosol Liver cancer:2.66e-4 (unfavourable) Expressed in all Expressed in all testis: 41.2 Expressed in all +DCTN1 ENSG00000204843 Dynactin subunit 1 2 74361154-74392087 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009108, HPA034635 Approved Supported Intermediate filaments
Centrosome
Cytosol Renal cancer:2.34e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 209.3 Expressed in all +SPATA31A1 C9orf36, C9orf36A, DKFZP434B204, FAM75A1, FAM75A2, SPATA31A2 ENSG00000204849 SPATA31 subfamily A member 1 9 39355669-39361959 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 81 testis: 8.0 all non-specific tissues: 0.0 Not detected +PNMAL2 KIAA1183 ENSG00000204851 Paraneoplastic Ma antigen family like 2 19 46486906-46496498 Predicted intracellular proteins Evidence at protein level HPA054810 Enhanced Mixed Group enriched 5 adrenal gland: 12.1;cerebral cortex: 32.9 ovary: 4.3 Cell line enhanced AF22: 1.2;AN3-CA: 1.4;SH-SY5Y: 1.3 +TCTN1 FLJ21127, JBTS13, TECT1 ENSG00000204852 Tectonic family member 1 12 110614027-110649430 Disease related genes, Predicted secreted proteins Evidence at protein level HPA039687, HPA040036 Approved Approved Nucleoplasm
Actin filaments Endometrial cancer:1.13e-5 (favourable) Expressed in all Mixed fallopian tube: 42.2 Mixed +FAM216A C12orf24, HSU79274 ENSG00000204856 Family with sequence similarity 216 member A 12 110468364-110490385 Predicted intracellular proteins Evidence at protein level HPA038286 Enhanced Approved Actin filaments Renal cancer:4.18e-10 (unfavourable), Liver cancer:4.49e-5 (unfavourable) Expressed in all Group enriched 7 cerebral cortex: 16.2;testis: 61.1 appendix: 5.5 Mixed +ZBTB48 HKR3, ZNF855 ENSG00000204859 Zinc finger and BTB domain containing 48 1 6580001-6589280 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030417 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:5.19e-6 (favourable), Cervical cancer:1.04e-4 (favourable) Expressed in all Expressed in all testis: 32.9 Expressed in all +IGFL2 UNQ645 ENSG00000204866 IGF like family member 2 19 46143106-46161299 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA059137 Uncertain Approved Nucleoplasm
Plasma membrane Mixed Tissue enriched 6 skin: 35.5 parathyroid gland: 6.1 Cell line enriched 33 CACO-2: 68.3 +IGFL4 ENSG00000204869 IGF like family member 4 19 46039748-46077118 Predicted intracellular proteins Evidence at transcript level HPA047655 Approved Approved Cytosol Mixed Tissue enhanced skin: 8.2 cerebral cortex: 2.6 Cell line enhanced A549: 3.5;HaCaT: 3.0 +KRTAP9-3 KAP9.3 ENSG00000204873 Keratin associated protein 9-3 17 41232463-41233454 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP4-8 KAP4.8 ENSG00000204880 Keratin associated protein 4-8 17 41096981-41098141 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +GPR20 ENSG00000204882 G protein-coupled receptor 20 8 141356500-141367267 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Mixed smooth muscle: 1.2 Cell line enhanced EFO-21: 2.1 +KRTAP1-4 KAP1.4 ENSG00000204887 Keratin associated protein 1-4 17 41029697-41030104 Predicted intracellular proteins Evidence at transcript level Not detected Not detected skin: 0.1 Not detected +KRT40 FLJ36600, KA36 ENSG00000204889 Keratin 40 17 40977716-40987135 Predicted intracellular proteins Evidence at protein level Tissue enhanced Not detected lung: 0.2 Not detected +KRT25 KRT25A ENSG00000204897 Keratin 25 17 40748021-40755332 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053977, HPA058943 Enhanced Approved Vesicles Not detected Group enriched 15 breast: 3.6;testis: 1.6 smooth muscle: 0.1 Cell line enriched 5 RPTEC TERT1: 1.0 +MZT1 C13orf37, FLJ21869, LOC440145, MGC150539, MOZART1, RP11-11C5.2 ENSG00000204899 Mitotic spindle organizing protein 1 13 72708357-72727687 Predicted intracellular proteins Evidence at protein level HPA063299, HPA066715 Approved Renal cancer:1.01e-5 (unfavourable), Liver cancer:3.22e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 30.1 Expressed in all +SPINK9 ENSG00000204909 Serine peptidase inhibitor, Kazal type 9 5 148321203-148339849 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038288 Uncertain Tissue enhanced Mixed testis: 10.6 Mixed +LRRC3C ENSG00000204913 Leucine rich repeat containing 3C 17 39941474-39944747 Predicted membrane proteins Evidence at protein level HPA071271 Uncertain Not detected Not detected testis: 0.9 Not detected +PRR20B ENSG00000204918 Proline rich 20B 13 57147488-57150509 Predicted intracellular proteins No evidence HPA059485 Uncertain Not detected Not detected testis: 0.1 Not detected +PRR20A FLJ40296, PRR20 ENSG00000204919 Proline rich 20A 13 57140918-57143939 Predicted intracellular proteins Evidence at transcript level HPA059485 Uncertain Not detected Not detected testis: 0.1 Not detected +ZNF155 pHZ-96 ENSG00000204920 Zinc finger protein 155 19 43967862-43998325 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003220 Uncertain Approved Nucleoplasm
Cytosol Mixed Mixed parathyroid gland: 14.5 Mixed +UQCC3 C11orf83, UNQ655 ENSG00000204922 Ubiquinol-cytochrome c reductase complex assembly factor 3 11 62670273-62673687 Disease related genes, Predicted membrane proteins Evidence at protein level HPA046851 Approved Approved Nucleoplasm
Mitochondria
Cytosol Liver cancer:2.55e-4 (unfavourable) Expressed in all Expressed in all prostate: 8.8 Expressed in all +FBXO48 ENSG00000204923 F-box protein 48 2 68459419-68467258 Predicted intracellular proteins Evidence at protein level HPA049775, HPA054782 Uncertain Approved Nuclear bodies Expressed in all Mixed skin: 3.0 Mixed +GRXCR2 DFNB101 ENSG00000204928 Glutaredoxin and cysteine rich domain containing 2 5 145858521-145937126 Disease related genes, Predicted intracellular proteins Evidence at transcript level HPA059421 Uncertain Not detected Tissue enhanced testis: 1.6 skin: 0.6 Not detected +FAM221B C9orf128 ENSG00000204930 Family with sequence similarity 221 member B 9 35816391-35828747 Predicted intracellular proteins Evidence at transcript level HPA023011, HPA026577 Uncertain Not detected Group enriched 6 bone marrow: 2.4;testis: 10.3 prostate: 1.1 Not detected +CD177 HNA2A, NB1, PRV1 ENSG00000204936 CD177 molecule 19 43353659-43363172 Predicted secreted proteins Evidence at protein level HPA041820, HPA046601 Enhanced Cervical cancer:3.66e-4 (favourable) Tissue enhanced Group enriched 16 bone marrow: 193.1;colon: 155.7;prostate: 105.4;rectum: 181.9 appendix: 9.7 Cell line enriched 23 RPMI-8226: 65.6 +PSG5 FL-NCA-3, PSG ENSG00000204941 Pregnancy specific beta-1-glycoprotein 5 19 43166256-43186536 Predicted secreted proteins Evidence at protein level HPA046327 Approved Mixed Tissue enriched 108 placenta: 157.6 smooth muscle: 1.4 Group enriched 8 BJ: 363.6;fHDF/TERT166: 1157.5 +ZNF783 DKFZp667J212 ENSG00000204946 Zinc finger family member 783 7 149262171-149297302 Predicted intracellular proteins Evidence at protein level HPA020375 Uncertain Approved Plasma membrane
Cytosol Renal cancer:2.24e-7 (unfavourable), Urothelial cancer:4.11e-4 (favourable) Expressed in all Mixed spleen: 9.2 Mixed +ZNF425 ENSG00000204947 Zinc finger protein 425 7 149102784-149126346 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020087 Uncertain Supported Nucleus Mixed Mixed parathyroid gland: 5.5 Mixed +LRRC10B ENSG00000204950 Leucine rich repeat containing 10B 11 61508800-61511018 Predicted intracellular proteins Evidence at protein level HPA047619 Uncertain Approved Nucleoplasm
Nucleoli Mixed Tissue enriched 12 fallopian tube: 47.3 lung: 3.9 Group enriched 7 AF22: 9.8;RH-30: 10.4;SCLC-21H: 6.5 +FBXO47 ENSG00000204952 F-box protein 47 17 38936432-38967402 Predicted intracellular proteins Evidence at transcript level HPA057438 Uncertain Not detected Tissue enriched 72 testis: 7.2 all non-specific tissues: 0.0 Not detected +C12orf73 DKFZp547P055, FLJ13975 ENSG00000204954 Chromosome 12 open reading frame 73 12 103950202-103965708 Predicted secreted proteins Evidence at protein level HPA038883 Uncertain Approved Plasma membrane
Centrosome
Mitochondria Urothelial cancer:1.61e-4 (favourable), Liver cancer:6.98e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 17.8 Expressed in all +PCDHGA1 PCDH-GAMMA-A1 ENSG00000204956 Protocadherin gamma subfamily A, 1 5 141330571-141512981 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580, HPA036547 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Mixed Tissue enhanced cerebral cortex: 3.2 testis: 1.3 Cell line enhanced LHCN-M2: 3.7;T-47d: 6.9 +BLACE ENSG00000204960 B-cell acute lymphoblastic leukemia expressed 7 155356985-155367934 Predicted intracellular proteins Evidence at transcript level HPA041918 Uncertain Tissue enriched Not detected bone marrow: 0.3 Cell line enhanced HL-60: 1.2;NB-4: 1.6;REH: 6.9;U-937: 2.6 +PCDHA9 KIAA0345, PCDH-ALPHA9 ENSG00000204961 Protocadherin alpha 9 5 140847463-141012344 Plasma proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced testis: 1.2 cerebral cortex: 0.6 Cell line enriched 8 SCLC-21H: 6.7 +PCDHA8 ENSG00000204962 Protocadherin alpha 8 5 140841187-141012344 Predicted membrane proteins Evidence at protein level HPA044585 Uncertain Not detected Not detected cerebral cortex: 0.7 Group enriched 5 AN3-CA: 13.9;SCLC-21H: 4.9 +PCDHA7 CNR4, CNRS4, CRNR4 ENSG00000204963 Protocadherin alpha 7 5 140834248-141012344 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 1.6;testis: 1.0 endometrium,gallbladder,smooth muscle: 0.3 Cell line enhanced NTERA-2: 1.0;WM-115: 1.0 +PCDHA5 CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5 ENSG00000204965 Protocadherin alpha 5 5 140821604-141012344 Predicted membrane proteins Evidence at transcript level HPA044557 Approved Not detected Tissue enriched 10 cerebral cortex: 4.1 endometrium: 0.4 Cell line enhanced A549: 1.2;EFO-21: 3.4;T-47d: 3.5;WM-115: 1.4 +PCDHA4 CNR1, CNRN1, CRNR1, PCDH-ALPHA4 ENSG00000204967 Protocadherin alpha 4 5 140806929-141012344 Predicted membrane proteins Evidence at protein level HPA043180, HPA073478 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Not detected Tissue enhanced cerebral cortex: 4.4 gallbladder: 2.5 Cell line enhanced A549: 5.9;AF22: 6.1;EFO-21: 5.0;T-47d: 5.1 +PCDHA2 ENSG00000204969 Protocadherin alpha 2 5 140794852-141012344 Predicted membrane proteins Evidence at protein level HPA035653 Uncertain Not detected Not detected cerebral cortex: 0.9 Cell line enhanced AF22: 4.4;SH-SY5Y: 1.3;T-47d: 1.1;WM-115: 1.0 +PCDHA1 ENSG00000204970 Protocadherin alpha 1 5 140786136-141012347 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035969 Enhanced Approved Plasma membrane Not detected Tissue enhanced cerebral cortex: 2.8;testis: 1.4 adrenal gland: 0.4 Cell line enriched 6 T-47d: 8.6 +TRIM13 DLEU5, Leu5, RFP2, RNF77 ENSG00000204977 Tripartite motif containing 13 13 49995888-50020481 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000367 Enhanced Expressed in all Expressed in all testis: 141.2 Expressed in all +ERICH4 C19orf69, LOC100170765 ENSG00000204978 Glutamate rich 4 19 41443158-41444765 Predicted intracellular proteins Evidence at transcript level HPA042632, HPA048484 Uncertain Approved Nucleoplasm
Cytosol Mixed Group enriched 27 duodenum: 42.8;kidney: 16.3;small intestine: 42.9 lung: 1.2 Group enriched 13 CACO-2: 2.1;Hep G2: 4.2;THP-1: 1.1 +MS4A13 ENSG00000204979 Membrane spanning 4-domains A13 11 60515413-60542721 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA045017, HPA063626 Uncertain Not detected Tissue enriched 54 testis: 5.3 all non-specific tissues: 0.0 Cell line enhanced U-266/70: 1.4 +PRSS1 TRY1 ENSG00000204983 Protease, serine 1 7 142749468-142753076 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025487, CAB025538, HPA062452, HPA063471 Enhanced Endometrial cancer:6.41e-6 (unfavourable), Thyroid cancer:4.91e-4 (favourable), Ovarian cancer:7.05e-4 (favourable) Tissue enriched Tissue enriched 318 pancreas: 81683.0 ovary: 257.2 Cell line enhanced EFO-21: 1.3;RPMI-8226: 2.0;U-2 OS: 1.7 +SPIRE2 KIAA1832, spir-2 ENSG00000204991 Spire type actin nucleation factor 2 16 89818179-89871319 Predicted intracellular proteins Evidence at protein level HPA041413, HPA049415 Uncertain Approved Nucleus
Vesicles
Intermediate filaments Liver cancer:9.77e-5 (unfavourable) Expressed in all Mixed stomach: 14.0 Mixed +AARD C8orf85, LOC441376 ENSG00000205002 Alanine and arginine rich domain containing protein 8 116938199-116944487 Predicted intracellular proteins Evidence at protein level HPA068290 Approved Lipid droplets Tissue enriched Tissue enriched 8 testis: 42.4 breast: 5.4 Cell line enhanced HDLM-2: 20.1;SK-BR-3: 8.9;U-2 OS: 6.0 +PABPN1L ePABP2 ENSG00000205022 Poly(A) binding protein nuclear 1 like, cytoplasmic 16 88863333-88866660 Predicted intracellular proteins Evidence at transcript level HPA043415 Uncertain Not detected Tissue enhanced adrenal gland: 1.0 bone marrow: 0.5 Cell line enhanced MCF7: 2.0;NB-4: 1.1;SCLC-21H: 5.5;T-47d: 1.3 +OR5D16 ENSG00000205029 Olfactory receptor family 5 subfamily D member 16 11 55838752-55839738 G-protein coupled receptors, Predicted membrane proteins No evidence HPA046711 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR5L2 HSHTPCRX16, HTPCRX16 ENSG00000205030 Olfactory receptor family 5 subfamily L member 2 11 55827219-55828154 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047524 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +PKHD1L1 ENSG00000205038 Polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 8 109362477-109530330 Predicted membrane proteins Evidence at protein level HPA044458 Uncertain Endometrial cancer:7.61e-4 (favourable) Group enriched Group enriched 6 cervix, uterine: 21.3;fallopian tube: 19.7;thyroid gland: 57.2 endometrium: 5.5 Cell line enhanced HHSteC: 1.2;TIME: 1.3;U-266/70: 1.1 +SLFN12L ENSG00000205045 Schlafen family member 12 like 17 35464249-35537861 Predicted membrane proteins Evidence at protein level HPA024447 Uncertain Mixed Mixed spleen: 7.3 Cell line enhanced HDLM-2: 20.4;Karpas-707: 10.7 +CLLU1OS ENSG00000205057 Chronic lymphocytic leukemia up-regulated 1 opposite strand 12 92420094-92428148 Predicted intracellular proteins Evidence at transcript level Mixed Not detected lymph node,spleen,tonsil: 0.9 Cell line enriched 7 U-698: 4.3 +SLC35B4 FLJ14697, YEA4 ENSG00000205060 Solute carrier family 35 member B4 7 134289332-134317051 Predicted membrane proteins Evidence at protein level HPA049779 Approved Expressed in all Mixed cerebral cortex: 17.8 Expressed in all +LGALS7 GAL7, LGALS7A, PIG1, TP53I1 ENSG00000205076 Galectin 7 19 38770971-38773492 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001549, CAB032606 Enhanced Group enriched Group enriched 6 breast: 18.1;esophagus: 24.3;skin: 27.7 skeletal muscle: 3.6 Cell line enhanced HaCaT: 6.2;SCLC-21H: 1.2 +SYCE1L MRP2 ENSG00000205078 Synaptonemal complex central element protein 1 like 16 77199397-77213215 Predicted intracellular proteins Evidence at protein level HPA062464, HPA066691 Enhanced Intermediate filaments Renal cancer:2.11e-5 (unfavourable), Endometrial cancer:6.65e-4 (favourable) Mixed Tissue enriched 5 testis: 23.8 prostate: 4.6 Cell line enhanced HEK 293: 10.5 +TMEM231 ALYE870, FLJ22167, JBTS20, MKS11, PRO1886 ENSG00000205084 Transmembrane protein 231 16 75536744-75556286 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042081 Enhanced Approved Vesicles Mixed Tissue enriched 8 fallopian tube: 77.5 thyroid gland: 9.8 Mixed +FAM71F2 FAM137B ENSG00000205085 Family with sequence similarity 71 member F2 7 128672266-128683319 Predicted intracellular proteins Evidence at protein level HPA020513, HPA024248 Enhanced Approved Nucleoplasm Mixed Tissue enriched 22 testis: 42.9 adipose tissue,cerebral cortex: 1.9 Mixed +C2orf91 ENSG00000205086 Chromosome 2 open reading frame 91 2 41935368-41954266 Predicted intracellular proteins Evidence at transcript level HPA042517 Uncertain Tissue enriched Tissue enhanced lung: 2.5 adrenal gland: 1.0 Group enriched 6 AN3-CA: 3.8;HDLM-2: 13.8 +CCNI2 FLJ16793 ENSG00000205089 Cyclin I family member 2 5 132747445-132754403 Predicted intracellular proteins Evidence at transcript level HPA056288 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Colorectal cancer:8.21e-4 (favourable) Tissue enhanced Mixed duodenum: 3.8 Cell line enriched 6 MOLT-4: 21.8 +TMEM240 C1orf70, SCA21 ENSG00000205090 Transmembrane protein 240 1 1535174-1540453 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066721 Supported Pancreatic cancer:2.52e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 18.6 endometrium: 7.7 Cell line enhanced SCLC-21H: 12.1;SH-SY5Y: 13.3 +FRG2 FRG2A ENSG00000205097 FSHD region gene 2 4 190024351-190027257 Predicted intracellular proteins Evidence at transcript level HPA039264, HPA047769 Uncertain Not detected Not detected skin: 0.7 Not detected +FAM205A C9orf144B ENSG00000205108 Family with sequence similarity 205 member A 9 34723055-34729467 Predicted membrane proteins Evidence at protein level HPA071267 Enhanced Not detected Tissue enriched 321 testis: 39.5 skin: 0.1 Not detected +CDKL4 ENSG00000205111 Cyclin dependent kinase like 4 2 39175646-39229588 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA067895 Uncertain Not detected Tissue enriched 8 testis: 5.3 fallopian tube,placenta: 0.6 Cell line enhanced HL-60: 1.6;RT4: 1.1;SH-SY5Y: 2.8 +TMEM88B ENSG00000205116 Transmembrane protein 88B 1 1426128-1427787 Predicted membrane proteins Evidence at protein level HPA065743 Enhanced Tissue enhanced Tissue enriched 14 cerebral cortex: 11.8 testis: 0.8 Cell line enhanced Hep G2: 2.8;SCLC-21H: 1.9 +ACCSL ENSG00000205126 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like 11 44047981-44059977 Predicted intracellular proteins Evidence at transcript level Tissue enriched Not detected skin,testis: 0.4 Not detected +C4orf47 LOC441054 ENSG00000205129 Chromosome 4 open reading frame 47 4 185426249-185449826 Predicted intracellular proteins Evidence at transcript level HPA043662 Uncertain Approved Vesicles Renal cancer:4.75e-4 (unfavourable) Mixed Tissue enhanced fallopian tube: 21.6;testis: 24.2 thyroid gland: 7.8 Cell line enhanced U-87 MG: 5.8 +TRIQK C8orf83, DKFZp779L1068, LOC286144, PRO0845 ENSG00000205133 Triple QxxK/R motif containing 8 92883530-93017673 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA076853 Supported Endoplasmic reticulum Expressed in all Mixed thyroid gland: 39.2 Mixed +SDHAF1 LYRM8 ENSG00000205138 Succinate dehydrogenase complex assembly factor 1 19 35995199-35996315 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064277 Approved Mitochondria Renal cancer:2.11e-4 (favourable) Expressed in all Expressed in all duodenum: 13.8 Expressed in all +ARID3C ENSG00000205143 AT-rich interaction domain 3C 9 34621379-34628107 Predicted intracellular proteins, Transcription factors Evidence at transcript level Group enriched Tissue enriched 8 liver: 5.9 cerebral cortex: 0.7 Cell line enhanced HDLM-2: 1.8;Karpas-707: 1.8;T-47d: 2.4 +PSENEN PEN2 ENSG00000205155 Presenilin enhancer gamma-secretase subunit 19 35745114-35747519 Disease related genes, Predicted membrane proteins Evidence at protein level HPA047435 Approved Renal cancer:8.70e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 375.2 Expressed in all +C11orf91 ENSG00000205177 Chromosome 11 open reading frame 91 11 33698261-33700801 Predicted intracellular proteins Evidence at protein level HPA047064, HPA050487 Uncertain Supported Vesicles Not detected Tissue enhanced adipose tissue: 5.8;gallbladder: 7.7;testis: 6.9 esophagus: 3.3 Cell line enhanced HBEC3-KT: 11.7;hTERT-HME1: 7.8;HUVEC TERT2: 6.8;TIME: 10.3;U-2197: 9.7 +FABP9 PERF, PERF15, T-FABP ENSG00000205186 Fatty acid binding protein 9 8 81458341-81461579 Predicted intracellular proteins Evidence at protein level HPA073619 Approved Not detected Tissue enhanced breast: 1.6 adipose tissue: 0.7 Not detected +ZBTB10 FLJ12752, RINZF ENSG00000205189 Zinc finger and BTB domain containing 10 8 80485619-80526265 Predicted intracellular proteins Evidence at protein level HPA021554, HPA050569 Enhanced Enhanced Nucleoplasm Renal cancer:3.52e-4 (favourable) Expressed in all Expressed in all placenta: 25.2 Mixed +C4orf46 LOC201725, RCDG1 ENSG00000205208 Chromosome 4 open reading frame 46 4 158666679-158672255 Predicted intracellular proteins Evidence at protein level HPA047287, HPA052670 Uncertain Approved Nucleoplasm Expressed in all Tissue enhanced testis: 22.3 bone marrow: 8.4 Expressed in all +SCGB2B2 SCGB4A2, SCGBL ENSG00000205209 Secretoglobin family 2B member 2 19 34593329-34675699 Predicted secreted proteins Evidence at transcript level HPA046806 Uncertain Not detected Mixed epididymis: 3.2 Mixed +CCDC144NL MGC87631 ENSG00000205212 Coiled-coil domain containing 144 family, N-terminal like 17 20836447-20896140 Predicted intracellular proteins Evidence at transcript level HPA023457 Uncertain Approved Nucleus
Plasma membrane Not detected Tissue enriched 7 testis: 4.3 endometrium,prostate,seminal vesicle: 0.5 Cell line enriched 6 U-2 OS: 32.3 +LGR4 GPR48 ENSG00000205213 Leucine rich repeat containing G protein-coupled receptor 4 11 27365961-27472775 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA030267, HPA054350 Uncertain Approved Microtubule organizing center Renal cancer:2.00e-7 (favourable) Expressed in all Expressed in all kidney: 56.2 Cell line enhanced HAP1: 86.6 +PSMB10 beta2i, LMP10, MECL1, MGC1665 ENSG00000205220 Proteasome subunit beta 10 16 67934502-67937087 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030224, HPA030225, CAB034384 Enhanced Enhanced Cytosol Urothelial cancer:5.44e-4 (favourable) Expressed in all Expressed in all lymph node: 91.2 Mixed +VIT ENSG00000205221 Vitrin 2 36696690-36814792 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced ovary: 35.7 adipose tissue: 18.5 Cell line enhanced ASC diff: 23.1;ASC TERT1: 45.7;BJ: 27.8;fHDF/TERT166: 87.0;THP-1: 23.9 +SPDYE2 MGC119295 ENSG00000205238 Speedy/RINGO cell cycle regulator family member E2 7 102551232-102562308 Predicted intracellular proteins Evidence at protein level HPA051750 Approved Mixed Tissue enhanced testis: 15.0 skin: 4.1 Mixed +E2F4 E2F-4 ENSG00000205250 E2F transcription factor 4 16 67192169-67198918 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054128 Supported Nucleoplasm Expressed in all Expressed in all placenta: 64.2 Expressed in all +PDE7A HCP1 ENSG00000205268 Phosphodiesterase 7A 8 65717510-65842322 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB018770, HPA027340 Approved Renal cancer:1.35e-4 (unfavourable), Liver cancer:5.64e-4 (unfavourable) Expressed in all Expressed in all lymph node: 68.9 Expressed in all +TMEM170B ENSG00000205269 Transmembrane protein 170B 6 11538278-11583524 Predicted membrane proteins Evidence at transcript level HPA055134 Uncertain Approved Centrosome Mixed Tissue enhanced cerebral cortex: 21.3 bone marrow: 16.8 Cell line enhanced THP-1: 15.8 +MUC12 MUC11 ENSG00000205277 Mucin 12, cell surface associated 7 100969623-101018949 Predicted membrane proteins Evidence at protein level HPA023835 Enhanced Tissue enriched Group enriched 24 colon: 49.6;rectum: 74.4 appendix: 2.5 Not detected +CTXN3 ENSG00000205279 Cortexin 3 5 127649044-127658630 Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enriched 18 kidney: 78.6 skeletal muscle: 4.3 Not detected +MGAT4D GnT1IP ENSG00000205301 MGAT4 family member D 4 140442262-140498377 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036523 Enhanced Not detected Tissue enriched 66 testis: 49.0 epididymis: 0.7 Not detected +SNX2 ENSG00000205302 Sorting nexin 2 5 122774996-122830108 Predicted intracellular proteins Evidence at protein level HPA037400 Approved Enhanced Endosomes
Lysosomes Renal cancer:8.76e-7 (favourable), Liver cancer:7.90e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 124.4 Expressed in all +SAP25 FLJ00248 ENSG00000205307 Sin3A associated protein 25 7 100572228-100573820 Predicted intracellular proteins Evidence at protein level HPA062610 Uncertain Approved Nuclear bodies Mixed Tissue enhanced spleen: 48.2 lymph node: 32.7 Cell line enhanced HMC-1: 26.8;NB-4: 44.5;U-937: 21.3 +NT5M dNT-2, dNT2, mdN ENSG00000205309 5',3'-nucleotidase, mitochondrial 17 17303335-17347663 Predicted intracellular proteins Evidence at protein level HPA043777 Uncertain Ovarian cancer:8.42e-5 (favourable) Expressed in all Mixed testis: 4.8 Cell line enhanced U-266/70: 6.6 +SARNP CIP29, Hcc-1, THO1 ENSG00000205323 SAP domain containing ribonucleoprotein 12 55752463-55817756 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030902, HPA030903 Supported Supported Nuclear speckles Mixed Expressed in all testis: 92.7 Expressed in all +OR6C68 ENSG00000205327 Olfactory receptor family 6 subfamily C member 68 12 55492378-55493316 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected heart muscle: 0.2 Not detected +OR6C65 ENSG00000205328 Olfactory receptor family 6 subfamily C member 65 12 55400430-55401505 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR6C3 OST709 ENSG00000205329 Olfactory receptor family 6 subfamily C member 3 12 55331701-55332636 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR6C1 OST267 ENSG00000205330 Olfactory receptor family 6 subfamily C member 1 12 55320561-55321624 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ADGRG1 GPR56, TM7LN4, TM7XN1 ENSG00000205336 Adhesion G protein-coupled receptor G1 16 57610652-57665580 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA046065 Uncertain Renal cancer:5.52e-7 (favourable), Head and neck cancer:2.53e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 349.0 Cell line enhanced SK-MEL-30: 229.9 +IPO7 Imp7, RANBP7 ENSG00000205339 Importin 7 11 9384622-9448126 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA019002, HPA056590 Approved Approved Enhanced Nucleoplasm
Cytosol Pancreatic cancer:8.38e-6 (unfavourable), Cervical cancer:4.98e-4 (unfavourable), Liver cancer:6.57e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 89.8 Expressed in all +PRR13 DKFZP564J157, FLJ23818 ENSG00000205352 Proline rich 13 12 53441605-53446645 Predicted intracellular proteins Evidence at protein level HPA039396, HPA046219 Uncertain Enhanced Nucleoplasm Urothelial cancer:7.55e-4 (favourable), Cervical cancer:9.08e-4 (favourable) Expressed in all Expressed in all small intestine: 515.4 Expressed in all +TECPR1 DKFZP434B0335, FLJ23419, FLJ90593, KIAA1358 ENSG00000205356 Tectonin beta-propeller repeat containing 1 7 98214624-98252251 Predicted intracellular proteins Evidence at protein level HPA021061 Approved Supported Vesicles Pancreatic cancer:8.12e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 19.1 Expressed in all +MT1H MT1 ENSG00000205358 Metallothionein 1H 16 56669814-56671129 Predicted intracellular proteins Evidence at protein level Glioma:4.29e-7 (unfavourable), Renal cancer:5.44e-5 (unfavourable) Tissue enhanced Tissue enhanced kidney: 501.3;small intestine: 335.4;thyroid gland: 541.2 liver: 136.0 Cell line enhanced BEWO: 1.1;EFO-21: 3.4;SCLC-21H: 1.0 +SLCO6A1 CT48, MGC26949, OATP6A1, OATPY ENSG00000205359 Solute carrier organic anion transporter family member 6A1 5 102371782-102499016 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA054126 Enhanced Not detected Tissue enriched 136 testis: 54.0 placenta: 0.3 Not detected +MT1A MT1, MT1S ENSG00000205362 Metallothionein 1A 16 56638666-56640087 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB002161, CAB013056 Approved Expressed in all Tissue enhanced adipose tissue: 258.9 liver: 59.5 Cell line enhanced HMC-1: 26.0;hTEC/SVTERT24-B: 80.4;NTERA-2: 40.1 +C15orf59 INSYN1, LOC388135, MGC131524 ENSG00000205363 Chromosome 15 open reading frame 59 15 73735431-73752747 Predicted intracellular proteins Evidence at transcript level HPA041563 Approved Approved Nucleoplasm
Cytosol Renal cancer:5.38e-9 (favourable) Tissue enhanced Tissue enhanced cerebral cortex: 55.9 seminal vesicle: 19.8 Cell line enhanced ASC diff: 6.2;fHDF/TERT166: 4.8;HEK 293: 5.9;U-2 OS: 5.5 +MT1M MT1, MT1K ENSG00000205364 Metallothionein 1M 16 56632233-56633986 Predicted intracellular proteins Evidence at protein level Melanoma:2.13e-4 (unfavourable) Expressed in all Tissue enhanced adipose tissue: 110.2 small intestine: 47.6 Cell line enhanced ASC diff: 7.8;HAP1: 9.5;RPTEC TERT1: 38.2 +CFI C3b-INA, FI, IF, KAF ENSG00000205403 Complement factor I 4 109740694-109802179 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA001143, CAB016777, HPA024061 Supported Urothelial cancer:6.06e-4 (unfavourable) Expressed in all Tissue enhanced liver: 524.7 kidney: 221.8 Cell line enhanced CAPAN-2: 112.1;Hep G2: 117.9;HSkMC: 48.7;RPTEC TERT1: 139.4 +OR52E6 ENSG00000205409 Olfactory receptor family 52 subfamily E member 6 11 5840928-5841952 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.1 Not detected +SAMD9 C7orf5, FLJ20073, KIAA2004 ENSG00000205413 Sterile alpha motif domain containing 9 7 93099513-93118023 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021318, HPA021319 Approved Enhanced Vesicles
Cytosol Renal cancer:8.40e-7 (unfavourable), Pancreatic cancer:8.31e-5 (unfavourable), Lung cancer:2.93e-4 (unfavourable), Endometrial cancer:3.14e-4 (unfavourable) Expressed in all Tissue enhanced esophagus: 43.2 spleen: 24.2 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 64.9 +KRT6A CK6C, CK6D, K6C, K6D, KRT6C, KRT6D ENSG00000205420 Keratin 6A 12 52487174-52493257 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045697, HPA061168 Supported Approved Intermediate filaments Lung cancer:1.45e-4 (unfavourable) Tissue enhanced Tissue enriched 10 esophagus: 5703.6 tonsil: 564.5 Cell line enhanced HaCaT: 1007.5;HBEC3-KT: 1727.3;hTCEpi: 7036.9 +CNEP1R1 C16orf69, FLJ38101, NEP1-R1, TMEM188 ENSG00000205423 CTD nuclear envelope phosphatase 1 regulatory subunit 1 16 50024410-50037088 Predicted membrane proteins Evidence at protein level HPA042815, HPA077906 Uncertain Supported Cytosol Expressed in all Mixed testis: 32.8 Expressed in all +KRT81 Hb-1, KRTHB1 ENSG00000205426 Keratin 81 12 52285913-52291534 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049778 Supported Tissue enhanced Tissue enhanced breast: 3.8 placenta: 1.5 Cell line enhanced A-431: 2684.9;A549: 2072.1;PC-3: 1009.2;U-251 MG: 1766.1 +EXOC3L4 C14orf73 ENSG00000205436 Exocyst complex component 3 like 4 14 103100144-103110559 Predicted intracellular proteins Evidence at protein level HPA043661 Approved Colorectal cancer:1.43e-5 (unfavourable) Tissue enhanced Tissue enhanced duodenum: 19.2 small intestine: 10.7 Cell line enhanced HDLM-2: 3.5;HEL: 3.4;Hep G2: 1.8;RPMI-8226: 1.8 +KRTAP12-3 KRTAP12.3 ENSG00000205439 Keratin associated protein 12-3 21 44657932-44658341 Predicted intracellular proteins Evidence at protein level Not detected Not detected skin: 0.1 Not detected +IZUMO3 bA20A20.1, C9orf134 ENSG00000205442 IZUMO family member 3 9 24542952-24545946 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Tissue enriched 215 testis: 21.5 all non-specific tissues: 0.0 Cell line enriched 33 SCLC-21H: 3.3 +KRTAP10-2 KAP10.2, KAP18.2, KRTAP18-2 ENSG00000205445 Keratin associated protein 10-2 21 44550357-44551505 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +TP53TG3D ENSG00000205456 TP53 target 3D 16 32252719-32255922 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced epididymis: 4.2;testis: 4.2 adrenal gland,cerebral cortex: 1.1 Cell line enhanced AN3-CA: 1.1;HEL: 1.0;HMC-1: 1.2;RH-30: 1.0;SCLC-21H: 1.4;U-2 OS: 1.3 +TP53TG3C ENSG00000205457 TP53 target 3C 16 33193659-33196858 Predicted intracellular proteins Evidence at transcript level Not detected Not detected epididymis: 0.7 Not detected +ATP6AP1L ENSG00000205464 ATPase H+ transporting accessory protein 1 like 5 82279462-82386977 Predicted membrane proteins Evidence at transcript level HPA053771 Approved Approved Nucleoli
Cytosol Mixed Mixed testis: 10.3 Cell line enhanced MOLT-4: 14.2 +CCDC85C ENSG00000205476 Coiled-coil domain containing 85C 14 99500180-99604026 Predicted intracellular proteins Evidence at protein level HPA058346 Uncertain Approved Nuclear speckles
Cell Junctions Renal cancer:2.60e-5 (favourable), Endometrial cancer:1.44e-4 (unfavourable) Expressed in all Expressed in all esophagus: 31.1 Mixed +OR52J3 ENSG00000205495 Olfactory receptor family 52 subfamily J member 3 11 5046526-5047461 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR51A2 ENSG00000205496 Olfactory receptor family 51 subfamily A member 2 11 4954772-4955713 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR51A4 ENSG00000205497 Olfactory receptor family 51 subfamily A member 4 11 4946159-4947100 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +C2CD4B FAM148B, NLF2 ENSG00000205502 C2 calcium dependent domain containing 4B 15 62163535-62165283 Predicted intracellular proteins Evidence at transcript level HPA046880 Uncertain Cervical cancer:4.22e-4 (favourable) Mixed Tissue enhanced adipose tissue: 15.3 pancreas: 8.1 Cell line enhanced HUVEC TERT2: 1.6 +RGL3 FLJ32585 ENSG00000205517 Ral guanine nucleotide dissociation stimulator like 3 19 11384341-11419342 Predicted intracellular proteins Evidence at protein level HPA042763, HPA043615, HPA064578 Uncertain Uncertain Nucleus
Cytosol Renal cancer:6.61e-4 (favourable), Breast cancer:7.35e-4 (favourable) Mixed Group enriched 6 parathyroid gland: 128.2;thyroid gland: 36.8 seminal vesicle: 13.3 Cell line enhanced BEWO: 17.4;RT4: 17.3;T-47d: 14.8 +NAP1L4 NAP2 ENSG00000205531 Nucleosome assembly protein 1 like 4 11 2944431-2992377 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011567 Approved Supported Nucleoplasm Liver cancer:1.68e-7 (unfavourable), Thyroid cancer:1.55e-4 (favourable), Cervical cancer:9.77e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 148.6 Expressed in all +TMSB4X TB4X, TMSB4 ENSG00000205542 Thymosin beta 4, X-linked X 12975108-12977227 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033806 Approved Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:6.20e-4 (unfavourable) Expressed in all Expressed in all lymph node: 11540.2 Expressed in all +TMEM256 C17orf61, MGC40107 ENSG00000205544 Transmembrane protein 256 17 7402975-7404137 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA062732 Approved Vesicles Renal cancer:9.36e-4 (unfavourable) Expressed in all Expressed in all duodenum: 68.3 Expressed in all +C9orf92 Em:AL513424.1 ENSG00000205549 Chromosome 9 open reading frame 92 9 16203935-16276313 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced thyroid gland: 1.3 testis: 1.0 Cell line enhanced BJ hTERT+: 1.1;U-2197: 1.4 +CPT1B CPT1-M, M-CPT1 ENSG00000205560 Carnitine palmitoyltransferase 1B 22 50568861-50578465 Enzymes, Predicted membrane proteins Evidence at protein level HPA029583 Approved Mixed Expressed in all heart muscle: 106.5 Mixed +SMN2 BCD541, GEMIN1, SMNC, TDRD16B ENSG00000205571 Survival of motor neuron 2, centromeric 5 70049612-70078522 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB009344, HPA045271 Supported Expressed in all Mixed epididymis: 27.1 Cell line enhanced BEWO: 126.1 +SERF1B FAM2B, H4F5C ENSG00000205572 Small EDRK-rich factor 1B 5 70025247-70043113 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA075271 Approved Nuclear bodies Mixed Tissue enhanced testis: 48.0 epididymis: 31.8 Cell line enhanced SiHa: 111.5 +HMGN1 FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425 ENSG00000205581 High mobility group nucleosome binding domain 1 21 39342315-39349647 Predicted intracellular proteins Evidence at protein level CAB012260, HPA048694 Supported Supported Nucleus Renal cancer:8.74e-7 (unfavourable) Expressed in all Expressed in all tonsil: 218.1 Expressed in all +DENND6B AFI1B, FAM116B, MGC33692 ENSG00000205593 DENN domain containing 6B 22 50309030-50327060 Predicted intracellular proteins Evidence at protein level HPA018934, HPA021653, HPA029570 Uncertain Uncertain Plasma membrane Endometrial cancer:5.93e-5 (favourable), Colorectal cancer:1.41e-4 (unfavourable) Expressed in all Tissue enhanced fallopian tube: 21.5 cerebral cortex: 12.0 Mixed +EIF3CL ENSG00000205609 Eukaryotic translation initiation factor 3 subunit C-like 16 28379579-28403879 Predicted intracellular proteins Evidence at protein level HPA047097, HPA049495, HPA050112 Supported Approved Cytosol Group enriched Mixed skin: 24.2 Expressed in all +LCMT1 CGI-68, PPMT1 ENSG00000205629 Leucine carboxyl methyltransferase 1 16 25111729-25178231 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041559, HPA043530 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:7.53e-6 (favourable), Cervical cancer:2.78e-4 (favourable), Liver cancer:5.85e-4 (unfavourable) Expressed in all Expressed in all testis: 59.8 Expressed in all +MFSD2B ENSG00000205639 Major facilitator superfamily domain containing 2B 2 24010081-24063321 Predicted membrane proteins Evidence at protein level HPA044145 Enhanced Not detected Tissue enriched 9 bone marrow: 7.2 placenta: 0.7 Group enriched 16 HEL: 7.5;K-562: 3.3 +VCX3B VCX-C ENSG00000205642 Variable charge, X-linked 3B X 8464830-8466510 Predicted intracellular proteins Evidence at protein level HPA044996, HPA049357 Supported Tissue enhanced Tissue enriched 88 testis: 32.5 breast: 0.3 Cell line enriched 20 U-138 MG: 18.3 +CDPF1 C22orf40, LOC150383 ENSG00000205643 Cysteine rich DPF motif domain containing 1 22 46244011-46250679 Predicted intracellular proteins Evidence at protein level HPA018823 Uncertain Approved Nucleus
Cytosol Endometrial cancer:3.13e-5 (favourable) Expressed in all Mixed fallopian tube: 7.0 Mixed +HTN3 HIS2 ENSG00000205649 Histatin 3 4 70028413-70036538 Predicted secreted proteins, Transporters Evidence at protein level CAB073541 Enhanced Uncertain Vesicles Tissue enhanced Tissue enriched 1666 salivary gland: 47614.6 ovary: 28.5 Mixed +LIN52 C14orf46 ENSG00000205659 Lin-52 DREAM MuvB core complex component 14 74084796-74201235 Predicted intracellular proteins Evidence at protein level HPA000900, HPA001777 Uncertain Approved Nuclear speckles Liver cancer:6.08e-5 (unfavourable), Head and neck cancer:6.60e-4 (favourable) Expressed in all Mixed kidney: 17.3 Expressed in all +ARSH ENSG00000205667 Arylsulfatase family member H X 3006613-3033571 Predicted membrane proteins Evidence at transcript level Not detected Not detected epididymis: 0.9 Not detected +ACOT6 C14orf42 ENSG00000205669 Acyl-CoA thioesterase 6 14 73610945-73619888 Predicted intracellular proteins Evidence at protein level HPA058258 Uncertain Not detected Tissue enhanced kidney: 3.8 adipose tissue: 1.7 Cell line enriched 7 T-47d: 9.6 +SMIM11A C21orf51, FAM165B, SMIM11 ENSG00000205670 Small integral membrane protein 11A 21 34375480-34407866 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051321 Uncertain Approved Focal adhesion sites Not detected Mixed thyroid gland: 32.1 Mixed +TECRL DKFZp313B2333, DKFZp313D0829, GPSN2L, SRD5A2L2, TERL ENSG00000205678 Trans-2,3-enoyl-CoA reductase-like 4 64275257-64409468 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 18 heart muscle: 371.9 skeletal muscle: 20.5 Not detected +DPF3 BAF45c, cer-d4, Cerd4, FLJ14079 ENSG00000205683 Double PHD fingers 3 14 72619296-72894116 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA066790, HPA070601 Enhanced Enhanced Nucleoplasm Tissue enhanced Tissue enhanced ovary: 16.7 parathyroid gland: 10.0 Cell line enhanced BEWO: 17.1;HEL: 28.2 +MANSC4 ENSG00000205693 MANSC domain containing 4 12 27762738-27771276 Predicted membrane proteins Evidence at transcript level HPA039454, HPA039682 Uncertain Not detected Tissue enhanced testis: 3.2 placenta: 0.8 Cell line enhanced HUVEC TERT2: 1.2 +ETFRF1 LYRM5 ENSG00000205707 Electron transfer flavoprotein regulatory factor 1 12 25195216-25209645 Predicted intracellular proteins Evidence at protein level HPA044255 Approved Approved Microtubule organizing center Renal cancer:9.23e-5 (favourable), Breast cancer:9.63e-4 (favourable) Expressed in all Expressed in all testis: 112.5 Expressed in all +C17orf107 ENSG00000205710 Chromosome 17 open reading frame 107 17 4899418-4902932 Predicted intracellular proteins Evidence at transcript level HPA069713 Uncertain Approved Nucleus Breast cancer:5.06e-5 (favourable), Renal cancer:2.68e-4 (favourable), Pancreatic cancer:8.61e-4 (favourable) Mixed Mixed parathyroid gland,salivary gland: 5.7 Cell line enhanced fHDF/TERT166: 2.2;HMC-1: 3.2;hTCEpi: 2.4 +MBD3L4 ENSG00000205718 Methyl-CpG binding domain protein 3 like 4 19 7037748-7040179 Predicted intracellular proteins No evidence HPA051259 Uncertain Not detected Not detected testis: 0.1 Not detected +ITSN1 ITSN, MGC134948, MGC134949, SH3D1A, SH3P17 ENSG00000205726 Intersectin 1 21 33642400-33899861 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018007 Approved Supported Plasma membrane Expressed in all Expressed in all adipose tissue: 61.5 Expressed in all +ITPRIPL2 FLJ22994, LOC162073, MGC126798, MGC126800 ENSG00000205730 Inositol 1,4,5-trisphosphate receptor interacting protein like 2 16 19113932-19121629 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042011 Approved Centrosome Expressed in all Expressed in all skin: 27.8 Mixed +DENND1C FAM31C, FLJ22757 ENSG00000205744 DENN domain containing 1C 19 6467207-6482557 Predicted intracellular proteins Evidence at protein level HPA042758, HPA042839 Enhanced Renal cancer:7.51e-14 (favourable), Lung cancer:1.23e-4 (favourable), Urothelial cancer:5.62e-4 (favourable), Prostate cancer:8.95e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 28.2;lymph node: 37.1;spleen: 31.7 bone marrow: 14.0 Cell line enhanced Daudi: 16.1;HEL: 13.5;HMC-1: 39.4;U-937: 24.3 +SLCO1B7 LST3, SLC21A21 ENSG00000205754 Solute carrier organic anion transporter family member 1B7 (putative) 12 21015696-21092745 Predicted membrane proteins Evidence at transcript level HPA050892 Uncertain Not detected Tissue enriched 17 breast: 43.2 liver: 2.4 Cell line enhanced A-431: 2.3;A549: 1.6;CAPAN-2: 1.6;HeLa: 1.1;U-2 OS: 1.3 +CRLF2 CRL2, TSLPR ENSG00000205755 Cytokine receptor-like factor 2 X 1187549-1212750 Cancer-related genes, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced appendix: 2.1;gallbladder: 2.0 bone marrow: 1.0 Cell line enhanced HMC-1: 13.5;RPMI-8226: 2.8;U-698: 2.4 +CRYZL1 4P11, QOH-1 ENSG00000205758 Crystallin zeta like 1 21 33589341-33643926 Predicted intracellular proteins Evidence at protein level HPA019120, HPA029399, CAB034129 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 62.0 Expressed in all +C5orf51 LOC285636 ENSG00000205765 Chromosome 5 open reading frame 51 5 41904188-41921636 Predicted intracellular proteins Evidence at protein level HPA043779, HPA063816 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:1.90e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 27.1 Expressed in all +GAGE1 CT4.1 ENSG00000205777 G antigen 1 X 49589496-49608536 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Not detected Tissue enriched 748 testis: 110.5 duodenum: 0.1 Group enriched 7 AN3-CA: 2552.7;K-562: 597.3 +ARRDC5 ENSG00000205784 Arrestin domain containing 5 19 4890437-4902867 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 8 testis: 18.2 spleen: 2.3 Cell line enriched 19 REH: 1.9 +CYS1 ENSG00000205795 Cystin 1 2 10056780-10080944 Predicted intracellular proteins Evidence at protein level Renal cancer:1.27e-5 (favourable) Tissue enhanced Tissue enriched 6 kidney: 101.2 ovary: 15.7 Cell line enriched 14 RPTEC TERT1: 83.8 +PLPP6 FLJ46512, FLJ90191, PDP1, PPAPDC2 ENSG00000205808 Phospholipid phosphatase 6 9 4662315-4665258 Predicted membrane proteins Evidence at protein level HPA018096 Approved Approved Nucleoplasm
Vesicles Renal cancer:3.99e-4 (favourable) Expressed in all Mixed prostate: 26.7 Cell line enhanced HDLM-2: 92.6 +KLRC2 CD159c, NKG2-C ENSG00000205809 Killer cell lectin like receptor C2 12 10426854-10442300 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058052 Approved Plasma membrane Tissue enriched Group enriched 6 cerebral cortex: 17.3;spleen: 8.1 stomach: 2.1 Cell line enhanced HEL: 5.2;HeLa: 11.9;HSkMC: 3.0;U-87 MG: 2.8 +KLRC3 NKG2-E ENSG00000205810 Killer cell lectin like receptor C3 12 10412312-10420595 Predicted membrane proteins Evidence at transcript level HPA039910, HPA062570 Approved Uncertain Vesicles Tissue enriched Tissue enhanced cerebral cortex: 9.2;spleen: 6.2 lymph node: 2.3 Cell line enhanced HEL: 1.1;HeLa: 4.5;U-698: 1.3 +C16orf96 ENSG00000205832 Chromosome 16 open reading frame 96 16 4556490-4600714 Predicted intracellular proteins Evidence at protein level HPA042009, HPA042058 Uncertain Not detected Tissue enriched 21 testis: 10.9 cerebral cortex: 0.5 Not detected +GMNC GEMC1 ENSG00000205835 Geminin coiled-coil domain containing 3 190852877-190892429 Predicted intracellular proteins Evidence at protein level HPA043663 Uncertain Tissue enhanced Tissue enriched 5 fallopian tube: 9.5 testis: 1.8 Cell line enriched 10 SCLC-21H: 1.1 +TTC23L FLJ25439 ENSG00000205838 Tetratricopeptide repeat domain 23 like 5 34838833-34899456 Predicted intracellular proteins Evidence at protein level HPA037807 Enhanced Not detected Tissue enriched 7 testis: 39.2 fallopian tube: 5.8 Not detected +CLEC6A CLECSF10, dectin-2 ENSG00000205846 C-type lectin domain family 6 member A 12 8455926-8478330 Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enhanced appendix: 1.5;lung: 1.5 lymph node: 0.8 Cell line enhanced NTERA-2: 3.3 +RFPL3S NCRNA00005, RFPL3-AS, RFPL3-AS1 ENSG00000205853 RFPL3 antisense 22 32359906-32382052 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enriched 17 testis: 99.1 cerebral cortex: 5.8 Cell line enhanced U-266/84: 5.5 +C22orf42 ENSG00000205856 Chromosome 22 open reading frame 42 22 32149006-32159322 Predicted intracellular proteins Evidence at protein level HPA019531 Enhanced Group enriched Tissue enriched 8 testis: 10.8 prostate: 1.3 Not detected +NANOGNB ENSG00000205857 NANOG neighbor homeobox 12 7765216-7774121 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA060371 Uncertain Tissue enriched Not detected testis: 0.5 Not detected +LRRC72 ENSG00000205858 Leucine rich repeat containing 72 7 16526880-16581568 Predicted intracellular proteins Evidence at transcript level HPA020554 Uncertain Not detected Tissue enriched 44 testis: 4.3 all non-specific tissues: 0.0 Not detected +PCOTH C1QTNF9B-AS1 ENSG00000205861 Pro-X-Gly collagen triple helix like repeat containing 13 23888889-23897263 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enhanced prostate: 24.5;skin: 25.5;testis: 38.3 epididymis: 6.1 Cell line enhanced hTEC/SVTERT24-B: 11.5;LHCN-M2: 10.9 +C1QTNF9B CTRP9B ENSG00000205863 C1q and tumor necrosis factor related protein 9B 13 23890525-23902655 Predicted secreted proteins Evidence at protein level HPA056632 Uncertain Tissue enhanced Tissue enhanced skin: 9.4 testis: 3.3 Not detected +KRTAP5-6 KRTAP5.6 ENSG00000205864 Keratin associated protein 5-6 11 1697195-1697755 Predicted intracellular proteins Evidence at protein level Liver cancer:6.04e-5 (favourable) Tissue enriched Not detected placenta: 0.6 Not detected +KRTAP5-2 KRTAP5-8, KRTAP5.2 ENSG00000205867 Keratin associated protein 5-2 11 1597177-1598294 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced cerebral cortex: 3.6 gallbladder: 0.9 Cell line enhanced MCF7: 1.9;SCLC-21H: 3.3;SH-SY5Y: 1.3 +KRTAP5-1 KRN1L, KRTAP5.1 ENSG00000205869 Keratin associated protein 5-1 11 1584342-1585283 Predicted intracellular proteins Evidence at transcript level Colorectal cancer:2.37e-4 (unfavourable) Mixed Not detected adrenal gland,cerebral cortex,pancreas,salivary gland,small intestine,spleen,stomach: 0.1 Cell line enhanced SCLC-21H: 1.6 +DEFB134 ENSG00000205882 Defensin beta 134 8 11993174-11996312 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 8 epididymis: 36.9 testis: 4.6 Not detected +DEFB135 ENSG00000205883 Defensin beta 135 8 11982321-11984590 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 189 epididymis: 84.8 gallbladder,testis: 0.4 Cell line enhanced HEK 293: 1.1;MCF7: 3.5 +DEFB136 DEFB137 ENSG00000205884 Defensin beta 136 8 11973937-11974599 Predicted secreted proteins Evidence at protein level HPA068255 Enhanced Not detected Tissue enriched 9 epididymis: 3.8 seminal vesicle: 0.4 Cell line enhanced HEK 293: 1.0 +BHLHA9 bHLHa9, BHLHF42 ENSG00000205899 Basic helix-loop-helix family member a9 17 1270559-1271460 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062632 Uncertain Tissue enhanced Not detected cerebral cortex: 0.8 Not detected +ZNF316 ENST00000305834, MZF-3 ENSG00000205903 Zinc finger protein 316 7 6637322-6656432 Predicted intracellular proteins, Transcription factors Evidence at protein level Pancreatic cancer:6.03e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 50.8 Expressed in all +DAZ4 ENSG00000205916 Deleted in azoospermia 4 Y 24833843-24907040 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047113 Approved Not detected Group enriched 40 stomach: 22.3;testis: 21.5 skin: 0.5 Group enriched 123 U-266/70: 117.1;U-266/84: 107.2 +ONECUT3 ENSG00000205922 One cut homeobox 3 19 1752373-1780988 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059936 Supported Nucleoplasm Group enriched Tissue enhanced stomach: 4.0 gallbladder: 1.0 Group enriched 9 HaCaT: 6.2;PC-3: 14.4 +CEMP1 CP-23 ENSG00000205923 Cementum protein 1 16 2530035-2531417 Predicted intracellular proteins Evidence at transcript level HPA057658 Approved Not detected Mixed skin: 5.7 Cell line enhanced REH: 6.9 +OLIG2 BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17 ENSG00000205927 Oligodendrocyte transcription factor 2 21 33025845-33029196 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003254, CAB019381 Enhanced Uncertain Nucleoplasm
Plasma membrane Tissue enriched Tissue enriched 245 cerebral cortex: 91.0 duodenum: 0.3 Cell line enhanced HMC-1: 46.5;NB-4: 25.3;THP-1: 23.2;WM-115: 10.9 +C21orf62 B37, C21orf120, PRED81 ENSG00000205929 Chromosome 21 open reading frame 62 21 32793564-32813743 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA016899 Enhanced Renal cancer:1.14e-4 (favourable) Tissue enriched Tissue enhanced epididymis: 6.4;kidney: 5.1;ovary: 12.6 prostate: 4.2 Group enriched 13 AF22: 2.5;RPTEC TERT1: 1.1 +RNPS1 ENSG00000205937 RNA binding protein with serine rich domain 1 16 2253116-2268412 Predicted intracellular proteins, Transporters Evidence at protein level HPA044014 Approved Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 143.8 Expressed in all +DAZ2 MGC126442, pDP1678 ENSG00000205944 Deleted in azoospermia 2 Y 23219434-23291356 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047113 Approved Not detected Group enriched 27 stomach: 15.5;testis: 7.2 skin: 0.4 Cell line enriched 9 SK-MEL-30: 1.4 +NYNRIN CGIN1, FLJ11811, KIAA1305 ENSG00000205978 NYN domain and retroviral integrase containing 14 24398786-24419288 Predicted intracellular proteins Evidence at protein level HPA018945 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all Mixed ovary: 42.7 Cell line enhanced HUVEC TERT2: 28.9;RT4: 23.0 +DNAJC19 Pam18, Tim14, TIMM14 ENSG00000205981 DnaJ heat shock protein family (Hsp40) member C19 3 180983709-180989774 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037782 Approved Ovarian cancer:8.53e-5 (favourable) Expressed in all Expressed in all kidney: 52.9 Expressed in all +IFITM5 BRIL, fragilis4, Hrmp1 ENSG00000206013 Interferon induced transmembrane protein 5 11 298200-299526 Disease related genes, Predicted membrane proteins Evidence at protein level HPA039258 Uncertain Mixed Not detected bone marrow: 0.5 Not detected +SMIM21 C18orf62 ENSG00000206026 Small integral membrane protein 21 18 75409476-75427703 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041686 Enhanced Not detected Tissue enriched 52 testis: 5.2 all non-specific tissues: 0.0 Cell line enhanced U-87 MG: 1.1 +C18orf63 DKFZP781G0119 ENSG00000206043 Chromosome 18 open reading frame 63 18 74315813-74359187 Predicted intracellular proteins Evidence at protein level HPA042233 Approved Mitochondria Not detected Tissue enriched 62 testis: 17.8 breast: 0.2 Not detected +DEFA1 DEF1, DEFA2, HNP-1, MRS ENSG00000206047 Defensin alpha 1 8 6977649-6980080 Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB032548, HPA052517 Enhanced Not detected Tissue enriched 269 bone marrow: 30312.0 skin: 112.6 Cell line enriched 9 NB-4: 2.6 +DOK6 DOK5L, HsT3226, MGC20785 ENSG00000206052 Docking protein 6 18 69401055-69849087 Predicted intracellular proteins Evidence at protein level HPA041099, HPA063534 Approved Approved Focal adhesion sites
Cytosol Mixed Tissue enhanced cerebral cortex: 21.0 placenta: 8.5 Cell line enhanced fHDF/TERT166: 8.1;Hep G2: 7.6;RPMI-8226: 7.5;SCLC-21H: 5.6;SH-SY5Y: 11.3 +HN1L C16orf34, FLJ13092, KIAA1426, L11 ENSG00000206053 Hematological and neurological expressed 1 like 16 1678256-1702280 Predicted intracellular proteins Evidence at protein level HPA041888, HPA041908 Approved Enhanced Plasma membrane
Cytosol Endometrial cancer:7.85e-4 (favourable), Liver cancer:9.14e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 101.8 Expressed in all +TMEM211 bA9F11.1 ENSG00000206069 Transmembrane protein 211 22 24934954-24946695 Predicted membrane proteins Evidence at transcript level HPA066784 Uncertain Tissue enhanced Tissue enhanced cervix, uterine: 3.7;stomach: 2.7 salivary gland: 1.4 Not detected +SERPINB11 EPIPIN ENSG00000206072 Serpin family B member 11 (gene/pseudogene) 18 63647579-63726432 Plasma proteins, Predicted intracellular proteins Evidence at transcript level Tissue enhanced Group enriched 5 esophagus: 28.7;prostate: 49.9 tonsil: 7.2 Not detected +SERPINB4 LEUPIN, PI11, SCCA-2, SCCA1, SCCA2 ENSG00000206073 Serpin family B member 4 18 63637259-63644298 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048341, HPA049988, HPA055992 Supported Pancreatic cancer:5.48e-4 (unfavourable) Tissue enhanced Tissue enriched 5 esophagus: 98.3 urinary bladder: 19.5 Cell line enhanced HaCaT: 1.9;SiHa: 1.8;U-2197: 5.5 +SERPINB5 maspin, PI5 ENSG00000206075 Serpin family B member 5 18 63476761-63505085 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009570, HPA019025, HPA019132, HPA020136 Enhanced Supported Vesicles Pancreatic cancer:5.71e-6 (unfavourable), Lung cancer:1.54e-4 (unfavourable) Tissue enhanced Group enriched 5 esophagus: 220.2;skin: 261.8 breast: 44.2 Cell line enhanced HaCaT: 1048.4;HBEC3-KT: 281.3;hTCEpi: 583.7 +ZDHHC11B ENSG00000206077 Zinc finger DHHC-type containing 11B 5 710360-766952 Enzymes, Predicted membrane proteins Evidence at transcript level HPA057886, HPA069008 Uncertain Approved Lipid droplets Lung cancer:3.98e-4 (favourable) Mixed Mixed cerebral cortex: 6.2 Cell line enhanced HAP1: 2.8;SCLC-21H: 4.1;THP-1: 2.7 +KRTAP19-8 ENSG00000206102 Keratin associated protein 19-8 21 31038159-31038476 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.7 Not detected +KRTAP20-3 KAP19D, KAP20.3, KRTAP19P4 ENSG00000206104 Keratin associated protein 20-3 21 30642864-30643136 Predicted intracellular proteins No evidence HPA053598 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP20-4 KAP20.4 ENSG00000206105 Keratin associated protein 20-4 21 30620627-30620850 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 36 testis: 3.6 all non-specific tissues: 0.0 Cell line enriched 10 U-2 OS: 5.5 +KRTAP22-2 KAP22.2 ENSG00000206106 Keratin associated protein 22-2 21 30590105-30590397 Predicted intracellular proteins No evidence Not detected Not detected skin: 0.2 Not detected +KRTAP27-1 ENSG00000206107 Keratin associated protein 27-1 21 30337013-30337694 Predicted intracellular proteins Evidence at transcript level HPA021522, HPA048826 Approved Not detected Not detected all non-specific tissues: 0.0 Not detected +CFAP99 ENSG00000206113 Cilia and flagella associated protein 99 4 2418974-2462942 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 8 fallopian tube: 7.0;testis: 11.3 adrenal gland: 1.0 Not detected +GOLGA8O ENSG00000206127 Golgin A8 family member O 15 32445106-32455634 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced testis: 8.7 thyroid gland: 2.2 Group enriched 14 HEL: 18.7;U-937: 23.4 +TMEM191C ENSG00000206140 Transmembrane protein 191C 22 21466423-21471269 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 9 testis: 1.5 endometrium,lung,ovary: 0.1 Not detected +RNASE13 RAL1 ENSG00000206150 Ribonuclease A family member 13 (inactive) 14 21032820-21034785 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 248 epididymis: 380.3 salivary gland: 1.5 Not detected +HBA1 HBA-T3 ENSG00000206172 Hemoglobin subunit alpha 1 16 176680-177522 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB032534, HPA043780 Enhanced Tissue enhanced Group enriched 34 bone marrow: 17119.3;placenta: 3433.6 spleen: 303.5 Group enriched 51 HEL: 3255.0;K-562: 2173.8 +HBM HBAP2, HBK ENSG00000206177 Hemoglobin subunit mu 16 153892-166768 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 29 bone marrow: 269.1 placenta: 9.2 Not detected +ELOA2 HsT832, TCEB3B, TCEB3L ENSG00000206181 Elongin A2 18 47032572-47035621 Predicted intracellular proteins Evidence at protein level HPA041009, HPA043501, HPA048971, HPA049178, HPA050086 Approved Not detected Tissue enriched 44 testis: 4.3 all non-specific tissues: 0.0 Not detected +ATP10A ATP10C, ATPVA, ATPVC, KIAA0566 ENSG00000206190 ATPase phospholipid transporting 10A (putative) 15 25677273-25865172 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA041496, HPA042509 Uncertain Renal cancer:6.60e-5 (unfavourable) Expressed in all Mixed lung: 10.6 Cell line enhanced BJ: 16.3;fHDF/TERT166: 22.1;HMC-1: 16.2;SK-MEL-30: 20.1 +ANKUB1 C3orf16 ENSG00000206199 Ankyrin repeat and ubiquitin domain containing 1 3 149761100-149968385 Predicted intracellular proteins Evidence at transcript level HPA053749 Uncertain Not detected Tissue enriched 5 fallopian tube: 9.0 lung: 1.6 Not detected +TSSK2 FLJ38613, SPOGA2, STK22B ENSG00000206203 Testis specific serine kinase 2 22 19130808-19132623 Enzymes, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 290 testis: 120.4 ovary: 0.4 Cell line enhanced SCLC-21H: 1.0 +PRR23A ENSG00000206260 Proline rich 23A 3 139005468-139006268 Predicted intracellular proteins Evidence at transcript level HPA047473 Uncertain Tissue enriched Tissue enriched 10 testis: 1.9 ovary: 0.1 Not detected +FOXL2NB C3orf72, FLJ43329 ENSG00000206262 FOXL2 neighbor 3 138947234-138953451 Predicted intracellular proteins Evidence at protein level HPA061017, HPA071790 Supported Nucleoli fibrillar center Mixed Tissue enhanced endometrium: 29.1;ovary: 50.7;parathyroid gland: 63.8 fallopian tube: 19.5 Cell line enhanced AN3-CA: 4.1;fHDF/TERT166: 6.7;HEL: 7.8;SiHa: 7.1 +COL6A6 ENSG00000206384 Collagen type VI alpha 6 chain 3 130560334-130678155 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045239 Uncertain Tissue enhanced Tissue enhanced lung: 11.2 breast: 2.9 Not detected +RAB12 ENSG00000206418 RAB12, member RAS oncogene family 18 8609445-8639381 Predicted intracellular proteins Evidence at protein level HPA040727 Approved Approved Vesicles Expressed in all Expressed in all skeletal muscle: 67.4 Expressed in all +LRRC30 ENSG00000206422 Leucine rich repeat containing 30 18 7231125-7232047 Predicted intracellular proteins Evidence at transcript level HPA041039 Uncertain Not detected Tissue enriched 10 skeletal muscle: 5.6 esophagus: 0.5 Not detected +TMEM200C TTMA ENSG00000206432 Transmembrane protein 200C 18 5882072-5895955 Predicted membrane proteins Evidence at protein level HPA047253, HPA050490 Uncertain Approved Microtubules Tissue enhanced Tissue enhanced adrenal gland: 3.1;cerebral cortex: 3.5 salivary gland: 1.7 Cell line enhanced AF22: 6.1;NTERA-2: 4.7;PC-3: 20.4;U-2 OS: 11.5 +OR10C1 hs6M1-17, OR10C1P, OR10C2 ENSG00000206474 Olfactory receptor family 10 subfamily C member 1 (gene/pseudogene) 6 29439306-29440977 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA049336 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +TXNRD3NB TR2IT1, TXNRD3IT1, TXNRD3NT1 ENSG00000206483 Thioredoxin reductase 3 neighbor 3 126571789-126572636 Predicted intracellular proteins Evidence at transcript level HPA058257 Uncertain Not detected Not detected ovary,testis: 0.2 Not detected +HLA-A ENSG00000206503 Major histocompatibility complex, class I, A 6 29941260-29945884 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB078470 Supported Golgi apparatus
Plasma membrane Ovarian cancer:6.47e-4 (favourable), Endometrial cancer:9.59e-4 (favourable) Expressed in all Mixed gallbladder: 340.9 Cell line enhanced A-431: 1127.9 +HACD2 PTPLB ENSG00000206527 3-hydroxyacyl-CoA dehydratase 2 3 123490820-123585185 Enzymes, Predicted membrane proteins Evidence at protein level CAB019282 Approved Pancreatic cancer:9.59e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 68.9 Expressed in all +CFAP44 FLJ11142, WDR52 ENSG00000206530 Cilia and flagella associated protein 44 3 113286947-113441610 Predicted intracellular proteins Evidence at protein level HPA067258 Uncertain Urothelial cancer:7.09e-6 (favourable) Mixed Tissue enhanced testis: 14.4 fallopian tube: 13.7 Mixed +CD200R1L CD200R2, CD200RLa ENSG00000206531 CD200 receptor 1 like 3 112815709-112846856 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 46 testis: 4.9 epididymis: 0.1 Not detected +LNP1 NP3 ENSG00000206535 Leukemia NUP98 fusion partner 1 3 100401193-100456319 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047926 Approved Nuclear speckles
Vesicles
Cytosol Expressed in all Tissue enriched 6 testis: 47.9 cerebral cortex: 7.6 Mixed +OR5K3 ENSG00000206536 Olfactory receptor family 5 subfamily K member 3 3 98390666-98391631 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +VGLL3 VGL-3 ENSG00000206538 Vestigial like family member 3 3 86876388-86991119 Predicted intracellular proteins Evidence at protein level HPA054983 Approved Approved Nucleoli
Cytosol Tissue enhanced Tissue enhanced placenta: 57.8 adipose tissue: 24.4 Cell line enriched 5 U-2197: 482.9 +PRSS50 CT20, TSP50 ENSG00000206549 Protease, serine 50 3 46712115-46812574 Enzymes, Predicted secreted proteins Evidence at protein level HPA040768 Supported Mixed Tissue enhanced epididymis: 5.7;parathyroid gland: 4.1 skeletal muscle,testis,thyroid gland: 2.0 Not detected +TRIM71 LIN-41, LIN41 ENSG00000206557 Tripartite motif containing 71 3 32818018-32897826 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038141, HPA038142 Uncertain Approved Plasma membrane
Actin filaments
Focal adhesion sites Tissue enriched Tissue enriched 8 testis: 9.1 lung: 1.1 Group enriched 6 AF22: 31.1;BEWO: 91.3;CACO-2: 19.0;Hep G2: 43.4;NTERA-2: 84.2 +ZCWPW2 ZCW2 ENSG00000206559 Zinc finger CW-type and PWWP domain containing 2 3 28349146-28538122 Predicted intracellular proteins Evidence at protein level HPA035035, HPA039839 Uncertain Approved Nuclear speckles Mixed Tissue enhanced testis: 18.5 thyroid gland: 5.3 Mixed +ANKRD28 KIAA0379, PITK, PP6-ARS-A, PPP1R65 ENSG00000206560 Ankyrin repeat domain 28 3 15667236-15859771 Predicted intracellular proteins Evidence at protein level Renal cancer:2.85e-4 (favourable) Expressed in all Expressed in all epididymis: 33.9 Expressed in all +COLQ EAD ENSG00000206561 Collagen like tail subunit of asymmetric acetylcholinesterase 3 15450133-15521751 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045876 Approved Plasma membrane
Cell Junctions Mixed Tissue enhanced parathyroid gland: 19.4 fallopian tube: 17.6 Cell line enhanced BEWO: 13.9;HDLM-2: 4.5;U-937: 5.9 +METTL6 MGC24132 ENSG00000206562 Methyltransferase like 6 3 15381275-15440566 Predicted intracellular proteins Evidence at protein level HPA035166 Uncertain Approved Vesicles Liver cancer:2.66e-6 (unfavourable) Expressed in all Expressed in all testis: 33.8 Expressed in all +XKR4 KIAA1889 ENSG00000206579 XK related 4 8 55102389-55542054 Predicted membrane proteins, Transporters Evidence at protein level HPA025072, HPA028083 Uncertain Not detected Tissue enriched 6 cerebral cortex: 4.7 seminal vesicle: 0.8 Group enriched 9 REH: 2.3;RPTEC TERT1: 7.5 +GPX3 ENSG00000211445 Glutathione peroxidase 3 5 151020438-151028993 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB069456 Uncertain Stomach cancer:1.65e-4 (unfavourable) Expressed in all Expressed in all kidney: 11674.4 Cell line enriched 11 ASC diff: 5265.2 +DIO2 SelY, TXDI2 ENSG00000211448 Iodothyronine deiodinase 2 14 80197527-80387757 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA029544, HPA048002 Supported Nucleoplasm
Cytosol Endometrial cancer:4.62e-6 (favourable), Colorectal cancer:1.67e-4 (favourable) Tissue enhanced Group enriched 6 cervix, uterine: 269.4;thyroid gland: 601.2 esophagus: 70.3 Cell line enhanced BJ: 70.1;HeLa: 63.5;SiHa: 184.0 +SELENOH C11orf31, SELH ENSG00000211450 Selenoprotein H 11 57741250-57743554 Predicted intracellular proteins Evidence at protein level HPA048362 Uncertain Approved Nucleus
Nucleoli Ovarian cancer:1.80e-4 (favourable), Liver cancer:4.30e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 69.6 Expressed in all +DIO1 TXDI1 ENSG00000211452 Iodothyronine deiodinase 1 1 53891239-53911086 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Thyroid cancer:5.44e-4 (unfavourable) Group enriched Group enriched 30 kidney: 147.5;liver: 94.9;thyroid gland: 434.9 fallopian tube: 7.5 Group enriched 20 Hep G2: 23.0;SK-BR-3: 59.3 +STK38L KIAA0965, NDR2 ENSG00000211455 Serine/threonine kinase 38 like 12 27243968-27325959 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038623, HPA051324 Approved Approved Cytosol Pancreatic cancer:5.82e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 65.3 Expressed in all +SACM1L KIAA0851, SAC1 ENSG00000211456 SAC1 suppressor of actin mutations 1-like (yeast) 3 45689056-45745424 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039573, HPA069869 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:5.47e-7 (favourable) Expressed in all Expressed in all thyroid gland: 67.5 Expressed in all +TSN BCLF-1, REHF-1, TRSLN ENSG00000211460 Translin 2 121737103-121767853 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059561 Uncertain Liver cancer:3.06e-4 (unfavourable), Endometrial cancer:7.05e-4 (unfavourable) Expressed in all Expressed in all testis: 41.1 Expressed in all +SLC48A1 FLJ20489, hHRG-1, HRG1 ENSG00000211584 Solute carrier family 48 member 1 12 47753916-47782753 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA073994 Supported Vesicles Renal cancer:1.34e-6 (favourable), Liver cancer:9.39e-5 (unfavourable), Cervical cancer:4.27e-4 (favourable) Expressed in all Expressed in all thyroid gland: 79.5 Expressed in all +TSSK1B FKSG81, SPOGA4, STK22D, TSSK1 ENSG00000212122 Testis specific serine kinase 1B 5 113432554-113435031 Enzymes, Predicted membrane proteins Evidence at protein level HPA027827 Enhanced Not detected Tissue enriched 222 testis: 62.0 skin: 0.2 Not detected +PRR22 MGC24975 ENSG00000212123 Proline rich 22 19 5782960-5784765 Predicted intracellular proteins Evidence at protein level HPA044157 Enhanced Approved Nucleus
Vesicles
Cytosol Expressed in all Tissue enhanced testis: 21.9 skin: 4.9 Cell line enhanced HMC-1: 15.2 +TAS2R19 T2R19, T2R23, TAS2R23, TAS2R48 ENSG00000212124 Taste 2 receptor member 19 12 11021619-11022620 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level Tissue enhanced Not detected ovary: 0.2 Not detected +TAS2R50 T2R51 ENSG00000212126 Taste 2 receptor member 50 12 10985913-10986912 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +TAS2R14 T2R14, TRB1 ENSG00000212127 Taste 2 receptor member 14 12 10937406-11171573 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Mixed Mixed epididymis: 1.2 Not detected +TAS2R13 T2R13, TRB3 ENSG00000212128 Taste 2 receptor member 13 12 10907926-10909562 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZRSR1 U2AF1-RS1, U2AF1L1, U2AF1P, U2AF1RS1, U2AFBPL, ZC3H21 ENSG00000212643 Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 1 5 112891422-112893094 Predicted intracellular proteins Evidence at transcript level Not detected Mixed epididymis: 1.1 Mixed +KRTAP16-1 KAP16.1 ENSG00000212657 Keratin associated protein 16-1 17 41307700-41309253 Predicted intracellular proteins Evidence at protein level HPA070954 Supported Not detected Not detected bone marrow: 0.3 Not detected +KRTAP29-1 KAP29.2 ENSG00000212658 Keratin associated protein 29-1 17 41301826-41302851 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 21 HDLM-2: 2.0 +KRTAP9-6 KAP9.6, KRTAP9L2 ENSG00000212659 Keratin associated protein 9-6 17 41265339-41266641 Predicted intracellular proteins No evidence Not detected Not detected skin: 0.1 Not detected +CTAGE1 CT21.1, CT21.2, CTAGE, cTAGE-1, cTAGE-2 ENSG00000212710 Cutaneous T-cell lymphoma-associated antigen 1 18 22413601-22417915 Predicted membrane proteins Evidence at protein level HPA000387, HPA000922, CAB016204 Uncertain Not detected Tissue enriched 50 testis: 5.0 all non-specific tissues: 0.0 Not detected +C17orf51 FLJ12977, FLJ31874, FLJ33618 ENSG00000212719 Chromosome 17 open reading frame 51 17 21524790-21574458 Predicted intracellular proteins Evidence at protein level HPA052106 Enhanced Approved Nucleoplasm
Nuclear bodies
Vesicles Mixed Tissue enhanced cerebral cortex: 16.6 testis: 8.2 Mixed +KRTAP4-11 KAP4.11, KAP4.14, KRTAP4-14 ENSG00000212721 Keratin associated protein 4-11 17 41117181-41118360 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP4-9 KAP4.9 ENSG00000212722 Keratin associated protein 4-9 17 41105332-41106488 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP2-3 KAP2.3 ENSG00000212724 Keratin associated protein 2-3 17 41059240-41060114 Predicted intracellular proteins Evidence at protein level HPA059203 Supported Mixed Not detected all non-specific tissues: 0.0 Cell line enhanced BJ: 31.1;fHDF/TERT166: 17.2;HBF TERT88: 30.9;LHCN-M2: 34.2;U-2 OS: 16.1 +KRTAP2-1 KAP2.1A ENSG00000212725 Keratin associated protein 2-1 17 41046541-41047316 Predicted intracellular proteins Evidence at protein level HPA059203 Supported Not detected Not detected all non-specific tissues: 0.0 Not detected +FAM127C CXX1c, MAR8B ENSG00000212747 Family with sequence similarity 127 member C X 135020504-135022529 Predicted intracellular proteins Evidence at protein level Breast cancer:2.41e-5 (unfavourable), Stomach cancer:3.72e-4 (unfavourable) Expressed in all Mixed prostate: 17.7 Cell line enhanced U-2197: 63.0 +OR2A42 ENSG00000212807 Olfactory receptor family 2 subfamily A member 42 7 144231911-144232843 G-protein coupled receptors, Predicted membrane proteins No evidence HPA058272 Uncertain Not detected Not detected thyroid gland: 0.6 Not detected +RNF208 DKFZP761H1710 ENSG00000212864 Ring finger protein 208 9 137220247-137221581 Predicted intracellular proteins Evidence at protein level HPA021256, HPA021429 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:1.12e-8 (favourable) Expressed in all Tissue enhanced cerebral cortex: 25.1 adrenal gland: 7.4 Cell line enhanced MCF7: 42.5;REH: 40.9 +KRTAP3-3 KAP3.3 ENSG00000212899 Keratin associated protein 3-3 17 40993430-40994133 Predicted intracellular proteins Evidence at protein level HPA042992 Approved Tissue enhanced Not detected breast,skin: 0.1 Not detected +KRTAP3-2 KAP3.2 ENSG00000212900 Keratin associated protein 3-2 17 40999193-40999894 Predicted intracellular proteins Evidence at protein level HPA042992 Approved Not detected Tissue enriched 7 esophagus: 3.3 skin: 0.5 Not detected +KRTAP3-1 KAP3.1 ENSG00000212901 Keratin associated protein 3-1 17 41008521-41019324 Predicted intracellular proteins Evidence at protein level Tissue enhanced Not detected all non-specific tissues: 0.0 Cell line enhanced BJ: 2.1;CACO-2: 5.5;HaCaT: 1.6;Hep G2: 2.3;T-47d: 1.8 +MT-ND4L MTND4L, NAD4L, ND4L ENSG00000212907 Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L MT 10470-10766 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA075648 Supported Mitochondria Liver cancer:4.47e-4 (favourable) Expressed in all Expressed in all kidney: 23320.0 Expressed in all +MAP10 KIAA1383, MTR120 ENSG00000212916 Microtubule associated protein 10 1 232804892-232808407 Predicted intracellular proteins Evidence at protein level HPA052496, HPA073262 Approved Approved Nuclear bodies
Cleavage furrow Mixed Mixed testis: 5.8 Cell line enhanced THP-1: 6.8 +KRTAP12-4 KRTAP12.4 ENSG00000212933 Keratin associated protein 12-4 21 44654213-44654659 Predicted intracellular proteins Evidence at protein level Not detected Not detected testis: 0.1 Not detected +KRTAP10-3 KAP10.3, KAP18.3, KRTAP18-3 ENSG00000212935 Keratin associated protein 10-3 21 44557790-44558760 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP6-3 KAP6.3 ENSG00000212938 Keratin associated protein 6-3 21 30592440-30593075 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +POU5F1B OTF3C, OTF3P1, POU5F1P1 ENSG00000212993 POU class 5 homeobox 1B 8 127414290-127420069 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058267 Supported Nucleoplasm Tissue enhanced Not detected parathyroid gland: 0.7 Cell line enhanced hTERT-HME1: 1.1 +ZNF580 ENSG00000213015 Zinc finger protein 580 19 55635016-55643469 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054058 Approved Approved Nucleus Renal cancer:5.79e-6 (unfavourable), Pancreatic cancer:2.36e-5 (favourable), Liver cancer:5.63e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 38.1 Expressed in all +ZNF611 MGC5384 ENSG00000213020 Zinc finger protein 611 19 52702813-52735073 Predicted intracellular proteins, Transcription factors Evidence at transcript level Renal cancer:3.33e-4 (favourable) Mixed Mixed fallopian tube: 11.1 Mixed +KLK9 KLK-L3 ENSG00000213022 Kallikrein related peptidase 9 19 51003111-51009634 Cancer-related genes, Enzymes, Predicted secreted proteins Evidence at transcript level CAB025049 Uncertain Tissue enriched Not detected skin,tonsil: 0.8 Not detected +SYT3 ENSG00000213023 Synaptotagmin 3 19 50621307-50639827 Predicted membrane proteins Evidence at protein level Mixed Tissue enriched 10 cerebral cortex: 17.1 testis: 1.7 Cell line enhanced HEK 293: 7.1;HMC-1: 4.7;NTERA-2: 5.5;SH-SY5Y: 6.6;U-2 OS: 4.0 +NUP62 DKFZp547L134, FLJ20822, FLJ43869, IBSN, MGC841, p62, SNDI ENSG00000213024 Nucleoporin 62 19 49906825-49929763 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA005435, CAB020724 Enhanced Supported Nucleus
Nuclear membrane Renal cancer:5.71e-12 (unfavourable), Liver cancer:2.50e-7 (unfavourable) Expressed in all Expressed in all testis: 76.9 Expressed in all +SPHAR ENSG00000213029 S-phase response (cyclin related) 1 229304857-229305504 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +CGB8 ENSG00000213030 Chorionic gonadotropin beta subunit 8 19 49047638-49049106 Predicted secreted proteins Evidence at protein level HPA038925, HPA038934 Supported Approved Cytosol Tissue enhanced Tissue enriched 90 placenta: 29.2 parathyroid gland: 0.3 Group enriched 8 BEWO: 167.1;U-251 MG: 51.5 +DENND1B C1orf218, FAM31B, FLJ20054, MGC27044 ENSG00000213047 DENN domain containing 1B 1 197504748-197775696 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042586 Uncertain Supported Nuclear speckles
Cytosol Expressed in all Expressed in all parathyroid gland: 11.1 Mixed +SFT2D2 dJ747L4.C1.2, UNQ512 ENSG00000213064 SFT2 domain containing 2 1 168225938-168253025 Predicted membrane proteins Evidence at protein level HPA042207 Approved Liver cancer:4.86e-4 (unfavourable) Expressed in all Mixed bone marrow: 21.1 Expressed in all +FGFR1OP FOP ENSG00000213066 FGFR1 oncogene partner 6 166999182-167052713 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA071876 Supported Centrosome Renal cancer:7.32e-4 (unfavourable) Expressed in all Expressed in all testis: 105.4 Expressed in all +FAM106A FLJ11800 ENSG00000213077 Family with sequence similarity 106 member A 17 18524566-18526846 Predicted intracellular proteins Evidence at transcript level HPA056425 Uncertain Approved Nucleoplasm
Nuclear bodies Not detected Tissue enhanced testis: 7.3 bone marrow,placenta: 1.6 Mixed +SCAF8 KIAA1116, RBM16 ENSG00000213079 SR-related CTD associated factor 8 6 154733325-154834244 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035601, HPA035602 Enhanced Enhanced Nucleoplasm Ovarian cancer:6.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 45.1 Expressed in all +CFAP45 CCDC19, NESG1 ENSG00000213085 Cilia and flagella associated protein 45 1 159872364-159900163 Predicted intracellular proteins Evidence at protein level HPA042204, HPA043618 Enhanced Enhanced Nucleoplasm Tissue enhanced Group enriched 7 fallopian tube: 71.3;testis: 38.9 lung: 7.7 Cell line enhanced BEWO: 8.7;HEL: 11.0 +ACKR1 CCBP1, CD234, DARC, Dfy, FY, GPD ENSG00000213088 Atypical chemokine receptor 1 (Duffy blood group) 1 159203307-159206500 Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA016421, HPA017672 Enhanced Cervical cancer:2.52e-5 (favourable), Liver cancer:1.48e-4 (favourable), Thyroid cancer:9.76e-4 (unfavourable) Expressed in all Mixed adipose tissue: 112.8 Group enriched 6 HEL: 30.2;HSkMC: 23.2 +ZNF254 BMZF-5, HD-ZNF1, ZNF539, ZNF91L ENSG00000213096 Zinc finger protein 254 19 24033405-24129961 Predicted intracellular proteins, Transcription factors Evidence at transcript level Lung cancer:8.60e-4 (favourable), Urothelial cancer:9.96e-4 (favourable) Expressed in all Mixed thyroid gland: 29.3 Mixed +TCTEX1D2 MGC33212 ENSG00000213123 Tctex1 domain containing 2 3 196291219-196318299 Predicted intracellular proteins Evidence at protein level HPA049555 Approved Cytosol Renal cancer:6.23e-4 (unfavourable), Cervical cancer:7.83e-4 (favourable) Expressed in all Tissue enhanced fallopian tube: 49.2 testis: 39.1 Mixed +CRYGS CRYG8 ENSG00000213139 Crystallin gamma S 3 186538441-186546702 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035103 Uncertain Uncertain Cytosol Renal cancer:3.72e-9 (unfavourable), Urothelial cancer:2.73e-4 (favourable) Expressed in all Mixed lymph node,spleen: 4.1 Mixed +CRIP1 CRIP ENSG00000213145 Cysteine rich protein 1 14 105486317-105488947 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042462 Approved Uncertain Nuclear speckles
Centrosome
Cytosol Mixed Expressed in all small intestine: 546.1 Cell line enhanced A549: 1118.8;CAPAN-2: 599.1;HaCaT: 653.1;HDLM-2: 498.2;T-47d: 892.4 +KLHL23 FLJ37812, MGC22679, MGC2610 ENSG00000213160 Kelch like family member 23 2 169694488-169776989 Predicted intracellular proteins Evidence at protein level HPA047593 Approved Nucleoplasm
Actin filaments Renal cancer:2.43e-5 (unfavourable), Liver cancer:2.09e-4 (unfavourable) Expressed in all Expressed in all endometrium: 42.8 Cell line enhanced SCLC-21H: 98.2 +LINGO4 LRRN6D ENSG00000213171 Leucine rich repeat and Ig domain containing 4 1 151800264-151806154 Predicted membrane proteins Evidence at transcript level HPA060781 Uncertain Mixed Tissue enhanced adrenal gland: 2.2;skeletal muscle: 4.1 fallopian tube,prostate: 1.0 Not detected +FAM24B AC073585.2, MGC45962 ENSG00000213185 Family with sequence similarity 24 member B 10 122849078-122879641 Predicted intracellular proteins Evidence at protein level HPA052490 Supported Expressed in all Tissue enhanced kidney: 13.8 testis: 11.4 Group enriched 5 hTERT-HME1: 99.8;LHCN-M2: 139.2;TIME: 44.7 +TRIM59 Mrf1, RNF104, TRIM57, TSBF1 ENSG00000213186 Tripartite motif containing 59 3 160432445-160485773 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017750 Uncertain Approved Rods & Rings Pancreatic cancer:1.15e-5 (unfavourable), Cervical cancer:4.36e-4 (favourable) Mixed Mixed cerebral cortex: 18.3 Mixed +MLLT11 AF1Q ENSG00000213190 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 1 151057758-151068497 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000540 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:4.25e-12 (unfavourable), Endometrial cancer:4.26e-5 (unfavourable) Expressed in all Tissue enriched 5 cerebral cortex: 122.5 parathyroid gland: 24.0 Cell line enhanced AF22: 129.2;SH-SY5Y: 151.4 +ASIC3 ACCN3, DRASIC, TNaC1 ENSG00000213199 Acid sensing ion channel subunit 3 7 151048292-151052756 Predicted membrane proteins Evidence at protein level HPA049155, HPA054805 Enhanced Approved Nucleoplasm
Cytosol Tissue enhanced Tissue enhanced testis: 8.1 cerebral cortex: 5.8 Cell line enhanced U-266/70: 13.4 +GIMAP1 HIMAP1, IAN2, IMAP1, IMAP38 ENSG00000213203 GTPase, IMAP family member 1 7 150716557-150724284 Predicted membrane proteins Evidence at protein level HPA044887, HPA053441 Uncertain Supported Endoplasmic reticulum Liver cancer:1.09e-4 (favourable), Testis cancer:6.12e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 32.8 lymph node: 21.3 Group enriched 10 HUVEC TERT2: 12.1;MOLT-4: 7.0;TIME: 3.1 +CCDC183 bA216L13.7, KIAA1984, MGC15438 ENSG00000213213 Coiled-coil domain containing 183 9 136796350-136807741 Predicted intracellular proteins Evidence at transcript level HPA043812 Uncertain Mixed Tissue enriched 51 testis: 11.8 prostate: 0.2 Not detected +ARHGEF35 ARHGEF5L, CTAGE4, FLJ43692 ENSG00000213214 Rho guanine nucleotide exchange factor 35 7 144186083-144195655 Predicted intracellular proteins Evidence at protein level HPA044188, HPA045619, HPA045699 Supported Renal cancer:4.57e-4 (favourable), Liver cancer:5.77e-4 (unfavourable) Mixed Mixed thyroid gland: 44.5 Cell line enhanced A-431: 47.0;hTCEpi: 30.0;RPTEC TERT1: 41.9;WM-115: 28.8 +CSH2 CS-2, CSB, hCS-B ENSG00000213218 Chorionic somatomammotropin hormone 2 17 63872012-63873766 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043715 Supported Tissue enhanced Tissue enriched 193 placenta: 3932.3 smooth muscle: 20.4 Cell line enriched 27 BEWO: 7.7 +DNLZ bA413M3.2, C9orf151, HEP, RP11-413M3.2, TIMM15, ZIM17 ENSG00000213221 DNL-type zinc finger 9 136359480-136363789 Predicted intracellular proteins Evidence at protein level HPA062738 Enhanced Nucleoplasm
Mitochondria Not detected Expressed in all cerebral cortex: 13.6 Expressed in all +TCL1B TML1 ENSG00000213231 T-cell leukemia/lymphoma 1B 14 95686417-95692643 Predicted intracellular proteins Evidence at protein level HPA053163 Uncertain Approved Cytosol Tissue enriched Tissue enhanced lymph node: 2.4;testis: 3.6;tonsil: 2.2 placenta: 1.2 Cell line enriched 5 U-698: 337.9 +SUPT4H1 Spt4, SPT4H, Supt4a, SUPT4H ENSG00000213246 SPT4 homolog, DSIF elongation factor subunit 17 58345175-58353093 Predicted intracellular proteins Evidence at protein level HPA059748 Approved Nucleus Liver cancer:7.69e-5 (unfavourable) Expressed in all Expressed in all lymph node: 82.4 Expressed in all +TSGA13 ENSG00000213265 Testis specific 13 7 130668648-130687432 Predicted intracellular proteins Evidence at transcript level HPA022968 Uncertain Not detected Tissue enriched 100 testis: 21.0 fallopian tube: 0.2 Not detected +NRAS N-ras ENSG00000213281 Neuroblastoma RAS viral oncogene homolog 1 114704469-114716894 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010157, HPA049830 Uncertain Liver cancer:3.03e-7 (unfavourable), Pancreatic cancer:1.36e-4 (unfavourable), Renal cancer:7.87e-4 (unfavourable) Expressed in all Expressed in all placenta: 39.4 Expressed in all +LTC4S MGC33147 ENSG00000213316 Leukotriene C4 synthase 5 179793980-179796647 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced fallopian tube: 3.7 adipose tissue,adrenal gland: 2.0 Cell line enriched 6 HMC-1: 59.7 +ANKRD39 MGC41816 ENSG00000213337 Ankyrin repeat domain 39 2 96836611-96858095 Predicted intracellular proteins Evidence at protein level HPA042678 Approved Approved Nucleoplasm
Vesicles Renal cancer:6.78e-9 (unfavourable), Pancreatic cancer:6.12e-5 (favourable), Colorectal cancer:2.26e-4 (unfavourable), Urothelial cancer:5.21e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 17.2 Expressed in all +QTRT1 TGT ENSG00000213339 Queuine tRNA-ribosyltransferase catalytic subunit 1 19 10701430-10713437 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042695, HPA048651, HPA049440 Approved Approved Mitochondria Renal cancer:1.13e-6 (unfavourable), Cervical cancer:7.63e-5 (favourable), Pancreatic cancer:2.13e-4 (favourable), Head and neck cancer:4.90e-4 (favourable) Expressed in all Expressed in all thyroid gland: 25.5 Expressed in all +CHUK IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 ENSG00000213341 Conserved helix-loop-helix ubiquitous kinase 10 100188298-100229619 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA001402, CAB004240, CAB018564 Approved Supported Nucleoplasm
Vesicles
Cytosol Renal cancer:1.27e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 23.1 Expressed in all +MXD3 bHLHc13, MAD3 ENSG00000213347 MAX dimerization protein 3 5 177301461-177312757 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA070111 Approved Nucleus
Nucleoli Liver cancer:3.60e-4 (unfavourable) Expressed in all Tissue enhanced bone marrow: 24.2 skin: 12.6 Cell line enhanced HDLM-2: 162.8 +GSTM2 GST4 ENSG00000213366 Glutathione S-transferase mu 2 1 109668022-109709551 Enzymes, Predicted intracellular proteins Evidence at protein level CAB040547, HPA055972, HPA055973 Approved Enhanced Cytosol Lung cancer:9.70e-5 (favourable) Mixed Expressed in all ovary: 201.1 Cell line enhanced ASC TERT1: 82.2;HSkMC: 85.0 +COG8 DOR1, FLJ22315 ENSG00000213380 Component of oligomeric golgi complex 8 16 69320140-69339583 Predicted intracellular proteins Evidence at protein level HPA041406 Approved Renal cancer:2.47e-7 (favourable), Pancreatic cancer:3.12e-5 (favourable) Expressed in all Expressed in all testis: 29.9 Expressed in all +ARHGAP19 FLJ00194, MGC14258 ENSG00000213390 Rho GTPase activating protein 19 10 97222173-97292673 Predicted intracellular proteins Evidence at protein level HPA035777, HPA043231 Uncertain Supported Plasma membrane Renal cancer:7.47e-5 (unfavourable) Expressed in all Tissue enhanced testis: 34.2 lymph node: 15.8 Expressed in all +HAUS7 UCHL5IP, UIP1 ENSG00000213397 HAUS augmin like complex subunit 7 X 153447666-153495516 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003614 Approved Nucleoli
Plasma membrane
Centrosome
Cytosol Renal cancer:3.94e-4 (unfavourable), Cervical cancer:6.12e-4 (favourable) Expressed in all Mixed skin: 64.1 Expressed in all +LCAT ENSG00000213398 Lecithin-cholesterol acyltransferase 16 67939750-67944131 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044767 Approved Nucleoplasm Liver cancer:4.21e-8 (favourable), Renal cancer:1.71e-4 (unfavourable), Colorectal cancer:8.50e-4 (unfavourable) Expressed in all Expressed in all liver: 105.7 Cell line enhanced BEWO: 73.6 +MAGEA12 CT1.12, MAGE12 ENSG00000213401 MAGE family member A12 X 152733779-152737669 Predicted intracellular proteins Evidence at protein level Liver cancer:3.22e-4 (unfavourable) Tissue enhanced Tissue enriched 16 testis: 4.9 cerebral cortex: 0.3 Cell line enhanced HMC-1: 50.9;K-562: 80.1;PC-3: 38.7;SH-SY5Y: 51.2;U-2 OS: 91.2;U-266/70: 52.9 +PTPRCAP CD45-AP, LPAP ENSG00000213402 Protein tyrosine phosphatase, receptor type C associated protein 11 67435510-67438067 Predicted secreted proteins Evidence at protein level HPA043734 Enhanced Not detected Tissue enhanced appendix: 64.0;lymph node: 91.4;spleen: 84.9 tonsil: 29.0 Cell line enhanced Daudi: 161.8;HDLM-2: 148.3;MOLT-4: 110.0;NB-4: 409.0;U-698: 109.1 +PVRIG C7orf15, MGC2463 ENSG00000213413 Poliovirus receptor related immunoglobulin domain containing 7 100218241-100221490 Predicted membrane proteins Evidence at protein level HPA047497 Uncertain Approved Nucleoli
Endoplasmic reticulum Not detected Tissue enhanced lymph node: 20.5;spleen: 11.0 appendix: 8.4 Group enriched 23 Daudi: 69.1;MOLT-4: 86.0;U-698: 21.4 +KRTAP4-12 KAP4.12 ENSG00000213416 Keratin associated protein 4-12 17 41123091-41124167 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP2-4 KAP2.4 ENSG00000213417 Keratin associated protein 2-4 17 41065116-41065879 Predicted intracellular proteins Evidence at protein level HPA059203 Supported Not detected Not detected all non-specific tissues: 0.0 Not detected +GPC2 cerebroglycan, DKFZp547M109, FLJ38962 ENSG00000213420 Glypican 2 7 100169606-100177372 Predicted secreted proteins Evidence at protein level CAB025423, HPA053945 Uncertain Uncertain Nucleus
Nucleoli
Golgi apparatus Urothelial cancer:9.94e-4 (favourable) Mixed Tissue enhanced skin: 5.7;testis: 10.1 cerebral cortex: 3.4 Cell line enhanced AF22: 39.1;SH-SY5Y: 46.0 +KRT222 KA21, KRT222P, MGC45562 ENSG00000213424 Keratin 222 17 40654665-40665181 Predicted intracellular proteins Evidence at protein level HPA043708, HPA054586, HPA069774 Uncertain Approved Vesicles
Lipid droplets Mixed Tissue enhanced cerebral cortex: 10.0;epididymis: 6.0 gallbladder: 2.7 Cell line enriched 6 RPTEC TERT1: 8.8 +SIPA1 SPA1 ENSG00000213445 Signal-induced proliferation-associated 1 11 65638097-65650930 Predicted intracellular proteins Evidence at protein level CAB020833, HPA039867 Enhanced Approved Nucleus
Nucleoli
Golgi apparatus
Plasma membrane Renal cancer:3.52e-6 (unfavourable), Colorectal cancer:9.42e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 99.7 lymph node: 71.0 Expressed in all +ERV3-1 envR, ERV-R, ERV3, H-PLK, HERV-R ENSG00000213462 Endogenous retrovirus group 3 member 1 7 64990809-65006743 Predicted secreted proteins Evidence at protein level HPA017209, HPA046508 Enhanced Approved Vesicles Expressed in all Mixed adrenal gland: 39.8 Mixed +SYNJ2BP Arip2 ENSG00000213463 Synaptojanin 2 binding protein 14 70366496-70417061 Predicted membrane proteins Evidence at protein level HPA000866 Approved Supported Approved Mitochondria Renal cancer:1.11e-16 (favourable) Expressed in all Mixed parathyroid gland: 40.9 Mixed +ARL2 ARFL2 ENSG00000213465 ADP ribosylation factor like GTPase 2 11 65014113-65022184 Predicted intracellular proteins Evidence at protein level HPA044610 Supported Approved Nucleus
Nucleoli
Golgi apparatus
Focal adhesion sites
Cytosol Endometrial cancer:4.58e-4 (unfavourable), Prostate cancer:7.70e-4 (favourable) Expressed in all Expressed in all fallopian tube: 114.0 Expressed in all +TTLL13P FLJ46079, MGC33417, TTLL13 ENSG00000213471 Tubulin tyrosine ligase like 13, pseudogene 15 90249530-90265482 Predicted intracellular proteins Evidence at protein level HPA041305 Enhanced Not detected Tissue enriched 50 testis: 5.0 all non-specific tissues: 0.0 Not detected +GBP7 FLJ38822, GBP4L ENSG00000213512 Guanylate binding protein 7 1 89131751-89176040 Predicted intracellular proteins Evidence at protein level HPA051245 Uncertain Tissue enriched Tissue enriched 89 liver: 48.3 adrenal gland: 0.5 Not detected +RBMXL1 KAT3 ENSG00000213516 RNA binding motif protein, X-linked like 1 1 88979456-88992960 Predicted intracellular proteins Evidence at protein level HPA057707 Supported Approved Nucleoplasm Pancreatic cancer:7.26e-4 (unfavourable), Breast cancer:7.60e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 22.5 Expressed in all +SRA1 SRA, STRAA1 ENSG00000213523 Steroid receptor RNA activator 1 5 140537340-140558252 Predicted intracellular proteins Evidence at protein level HPA044598, HPA050153 Approved Supported Nucleoplasm
Microtubules
Cytosol Endometrial cancer:8.01e-6 (favourable) Expressed in all Mixed adrenal gland: 17.5 Expressed in all +TMEM110 MGC52022 ENSG00000213533 Transmembrane protein 110 3 52836219-52897596 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA051855 Uncertain Approved Cytosol Mixed Expressed in all fallopian tube: 21.0 Expressed in all +DNAJC9 JDD1, SB73 ENSG00000213551 DnaJ heat shock protein family (Hsp40) member C9 10 73183362-73248862 Predicted intracellular proteins Evidence at protein level HPA035215, HPA035216 Enhanced Supported Nucleoplasm
Plasma membrane Prostate cancer:7.07e-5 (unfavourable), Lung cancer:3.26e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 37.4 Expressed in all +C8orf82 MGC70857 ENSG00000213563 Chromosome 8 open reading frame 82 8 144525733-144529132 Predicted intracellular proteins Evidence at protein level CAB034331 Uncertain Approved Nucleus Renal cancer:1.70e-5 (favourable) Expressed in all Expressed in all prostate: 33.3 Expressed in all +CPLX3 CPX-III ENSG00000213578 Complexin 3 15 74826547-74831802 Predicted intracellular proteins Evidence at protein level CAB079003 Supported Not detected Group enriched 8 prostate: 143.7;spleen: 74.6 cerebral cortex: 12.8 Cell line enhanced Daudi: 1.6;Karpas-707: 1.4;SCLC-21H: 1.0 +VDAC1 MGC111064, PORIN ENSG00000213585 Voltage dependent anion channel 1 5 133971915-134005133 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005885, HPA030780, CAB072343 Supported Approved Cytosol Lung cancer:2.87e-5 (unfavourable), Head and neck cancer:4.90e-4 (unfavourable), Breast cancer:5.30e-4 (unfavourable), Liver cancer:8.49e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 363.8 Expressed in all +ZBTB9 MGC23166, ZNF919 ENSG00000213588 Zinc finger and BTB domain containing 9 6 33453970-33457548 Predicted intracellular proteins Evidence at protein level HPA036767 Uncertain Approved Nucleus
Nucleoli
Mitochondria Not detected Mixed tonsil: 2.6 Cell line enhanced BEWO: 9.8;U-698: 8.1 +TMX2 PDIA12, TXNDC14 ENSG00000213593 Thioredoxin related transmembrane protein 2 11 57712600-57740973 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA040282, HPA063763 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.55e-5 (favourable), Urothelial cancer:3.37e-4 (unfavourable), Head and neck cancer:3.64e-4 (unfavourable), Liver cancer:4.11e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 129.2 Expressed in all +HEXA ENSG00000213614 Hexosaminidase subunit alpha 15 72340919-72376476 Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA054583 Supported Endometrial cancer:5.63e-8 (favourable) Expressed in all Expressed in all epididymis: 200.6 Mixed +NDUFS3 CI-30 ENSG00000213619 NADH:ubiquinone oxidoreductase core subunit S3 11 47565336-47584562 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004484 Approved Supported Nuclear bodies
Mitochondria Renal cancer:2.61e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 127.2 Expressed in all +LEPROT FLJ90360, OB-RGRP, OBRGRP, VPS55 ENSG00000213625 Leptin receptor overlapping transcript 1 65420587-65436007 Predicted membrane proteins Evidence at protein level HPA069444 Approved Centrosome Expressed in all Expressed in all placenta: 80.3 Expressed in all +LBH ENSG00000213626 Limb bud and heart development 2 30231531-30323730 Predicted intracellular proteins Evidence at protein level HPA034669 Approved Approved Vesicles Stomach cancer:8.24e-4 (unfavourable) Expressed in all Expressed in all lung: 197.1 Cell line enhanced fHDF/TERT166: 234.8;U-2 OS: 102.9 +ADAT3 TAD3 ENSG00000213638 Adenosine deaminase, tRNA specific 3 19 1905378-1913447 Predicted intracellular proteins Evidence at protein level HPA058899 Uncertain Approved Nucleus Head and neck cancer:6.13e-4 (favourable), Stomach cancer:6.98e-4 (favourable) Expressed in all Tissue enhanced duodenum: 7.5 small intestine: 5.3 Cell line enhanced HEK 293: 11.3 +PPP1CB PP-1B, PP1B, PP1beta ENSG00000213639 Protein phosphatase 1 catalytic subunit beta 2 28751640-28802940 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB022558, HPA065425, CAB069426 Supported Enhanced Nucleus
Plasma membrane Liver cancer:6.52e-6 (unfavourable) Expressed in all Expressed in all esophagus: 273.8 Expressed in all +SULT1A4 ENSG00000213648 Sulfotransferase family 1A member 4 16 29459889-29464976 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049500, HPA051051 Supported Not detected Tissue enhanced duodenum: 173.4;small intestine: 131.0 colon: 38.4 Cell line enhanced CAPAN-2: 107.9;EFO-21: 93.9;HEL: 76.5;Hep G2: 188.0;Karpas-707: 114.2 +GPSM3 AGS4, C6orf9, G18, G18.1a, G18.1b, G18.2, NG1 ENSG00000213654 G-protein signaling modulator 3 6 32190766-32195523 Predicted intracellular proteins Evidence at protein level Renal cancer:6.92e-9 (unfavourable), Endometrial cancer:5.98e-4 (favourable) Expressed in all Tissue enhanced lymph node: 27.5;spleen: 29.3 appendix: 24.9 Cell line enhanced HMC-1: 35.2;NB-4: 14.7;THP-1: 16.2 +LAT LAT1 ENSG00000213658 Linker for activation of T-cells 16 28984826-28990783 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB002223, HPA011157, CAB012978 Enhanced Supported Golgi apparatus
Plasma membrane Not detected Tissue enhanced lymph node: 75.3 appendix: 31.8 Group enriched 8 HEL: 173.8;HMC-1: 690.0;MOLT-4: 227.5 +NCKIPSD AF3P21, DIP1, ORF1, SPIN90, WASLBP, WISH ENSG00000213672 NCK interacting protein with SH3 domain 3 48673844-48686364 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB019267, HPA050005 Enhanced Plasma membrane
Cytosol Renal cancer:1.20e-5 (favourable), Liver cancer:8.57e-4 (unfavourable) Expressed in all Tissue enriched 9 parathyroid gland: 306.0 cerebral cortex: 35.0 Expressed in all +ATF6B CREBL1, G13 ENSG00000213676 Activating transcription factor 6 beta 6 32098176-32128253 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA046871 Uncertain Supported Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 56.8 Expressed in all +TREX1 AGS1, DRN3 ENSG00000213689 Three prime repair exonuclease 1 3 48465811-48467645 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA035437, HPA046721 Supported Supported Cytosol Not detected Expressed in all spleen: 30.9 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 66.5 +S1PR3 EDG-3, EDG3 ENSG00000213694 Sphingosine-1-phosphate receptor 3 9 88991447-89005010 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Renal cancer:7.91e-6 (unfavourable), Colorectal cancer:1.30e-4 (unfavourable), Breast cancer:5.91e-4 (favourable) Expressed in all Mixed smooth muscle: 52.4 Cell line enhanced AF22: 117.8;ASC diff: 111.7;ASC TERT1: 114.8 +SLC35F6 ANT2BP, C2orf18, FLJ20555, TANGO9 ENSG00000213699 Solute carrier family 35 member F6 2 26764284-26781231 Predicted membrane proteins, Transporters Evidence at protein level HPA034655 Approved Approved Nucleoplasm
Vesicles
Cytosol Liver cancer:1.11e-4 (unfavourable), Lung cancer:3.71e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 26.2 Expressed in all +FAM209B C20orf107, dJ1153D9.4 ENSG00000213714 Family with sequence similarity 209 member B 20 56533246-56536520 Predicted membrane proteins Evidence at protein level HPA042144 Enhanced Mixed Tissue enriched 22 testis: 112.5 bone marrow: 5.0 Mixed +CLIC1 G6, NCC27, p64CLCP ENSG00000213719 Chloride intracellular channel 1 6 31730581-31739763 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB020825, CAB040557 Enhanced Supported Cytosol Liver cancer:8.90e-7 (unfavourable), Renal cancer:8.11e-5 (unfavourable) Expressed in all Expressed in all rectum: 70.2 Expressed in all +DDAH2 G6A ENSG00000213722 Dimethylarginine dimethylaminohydrolase 2 6 31727038-31730617 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012509 Uncertain Uncertain Microtubule organizing center
Cytosol Expressed in all Mixed thyroid gland: 22.3 Cell line enhanced EFO-21: 23.0;U-2 OS: 18.9 +RPS29 S29 ENSG00000213741 Ribosomal protein S29 14 49570984-49599164 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA004107 Approved Supported Endoplasmic reticulum
Cytosol Breast cancer:2.66e-4 (favourable) Expressed in all Expressed in all breast: 3653.3 Expressed in all +UGT2B11 ENSG00000213759 UDP glucuronosyltransferase family 2 member B11 4 69199951-69214731 Enzymes, Predicted membrane proteins Evidence at transcript level HPA045108 Uncertain Group enriched Tissue enriched 17 breast: 320.4 gallbladder: 18.3 Not detected +ATP6V1G2 ATP6G, ATP6G2, Em:AC004181.3, NG38, Vma10 ENSG00000213760 ATPase H+ transporting V1 subunit G2 6 31544462-31548427 Predicted intracellular proteins Evidence at protein level CAB004616 Enhanced Tissue enriched Tissue enriched 12 cerebral cortex: 16.7 lymph node: 1.4 Cell line enhanced HDLM-2: 3.0;Karpas-707: 2.5 +ZNF134 pHZ-15 ENSG00000213762 Zinc finger protein 134 19 57614233-57624723 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009064 Supported Approved Nucleoplasm Cervical cancer:1.03e-4 (unfavourable), Renal cancer:2.61e-4 (favourable), Head and neck cancer:5.21e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 20.9 Mixed +GTF2H4 P52, TFB2, TFIIH ENSG00000213780 General transcription factor IIH subunit 4 6 30908184-30914106 Predicted intracellular proteins Evidence at protein level HPA074336 Supported Nuclear speckles Renal cancer:4.08e-4 (unfavourable) Expressed in all Mixed appendix: 3.6 Mixed +DDX47 DKFZp564O176, FLJ30012, HQ0256, RRP3 ENSG00000213782 DEAD-box helicase 47 12 12813316-12829981 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA014855 Approved Enhanced Nucleoli Mixed Expressed in all thyroid gland: 55.8 Expressed in all +ZNF888 ENSG00000213793 Zinc finger protein 888 19 52904417-52923481 Predicted intracellular proteins Evidence at transcript level Breast cancer:5.28e-4 (unfavourable) Mixed Mixed cervix, uterine: 18.3 Cell line enriched 5 RT4: 58.3 +ZNF845 ENSG00000213799 Zinc finger protein 845 19 53333749-53354869 Predicted intracellular proteins, Transcription factors Evidence at protein level Renal cancer:3.98e-4 (favourable) Expressed in all Mixed thyroid gland: 7.6 Mixed +KLRK1 CD314, D12S2489E, KLR, NKG2-D, NKG2D ENSG00000213809 Killer cell lectin like receptor K1 12 10372353-10391874 Cancer-related genes, CD markers, Predicted membrane proteins Evidence at protein level CAB021896, HPA068877 Enhanced Supported Plasma membrane Not detected Tissue enhanced lymph node: 35.1;spleen: 52.8 tonsil: 16.2 Cell line enriched 8 U-698: 41.6 +CEACAM18 ENSG00000213822 Carcinoembryonic antigen related cell adhesion molecule 18 19 51478622-51490952 Predicted secreted proteins Evidence at protein level HPA059487 Uncertain Approved Midbody Tissue enhanced Group enriched 14 duodenum: 10.5;small intestine: 7.2 gallbladder: 0.6 Group enriched 12 CACO-2: 3.6;RT4: 1.1 +EMP2 XMP ENSG00000213853 Epithelial membrane protein 2 16 10528422-10580698 Disease related genes, Predicted membrane proteins Evidence at protein level HPA014711 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.85e-8 (unfavourable), Glioma:1.93e-4 (unfavourable) Expressed in all Tissue enhanced lung: 343.9 skin: 166.6 Cell line enhanced MCF7: 205.4;SK-BR-3: 191.4 +KCTD11 C17orf36, KCASH1, REN ENSG00000213859 Potassium channel tetramerization domain containing 11 17 7351889-7354944 Enzymes, Predicted intracellular proteins Evidence at protein level HPA052035 Approved Approved Nucleoplasm Ovarian cancer:5.02e-4 (unfavourable), Endometrial cancer:9.55e-4 (favourable) Expressed in all Mixed esophagus: 39.8 Cell line enhanced HBEC3-KT: 38.4 +C8orf44 FLJ11267 ENSG00000213865 Chromosome 8 open reading frame 44 8 66667615-66685564 Predicted intracellular proteins Evidence at protein level HPA043660, HPA054753 Uncertain Enhanced Nucleoplasm Renal cancer:1.08e-7 (unfavourable), Urothelial cancer:2.68e-6 (favourable), Pancreatic cancer:4.21e-4 (favourable) Expressed in all Mixed epididymis: 21.2 Expressed in all +UBD FAT10 ENSG00000213886 Ubiquitin D 6 29555515-29559925 Predicted intracellular proteins Evidence at protein level HPA043710 Supported Nucleus
Nucleoli fibrillar center Renal cancer:2.40e-5 (unfavourable), Ovarian cancer:7.35e-4 (favourable) Expressed in all Tissue enhanced lymph node: 94.9;tonsil: 92.5 appendix: 43.0 Cell line enriched 6 RT4: 24.7 +PPM1N FLJ40125 ENSG00000213889 Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) 19 45488777-45502510 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043577 Supported Vesicles Tissue enhanced Tissue enriched 5 skeletal muscle: 69.9 spleen: 12.9 Cell line enhanced RT4: 24.0 +CEACAM16 DFNA4B ENSG00000213892 Carcinoembryonic antigen related cell adhesion molecule 16 19 44699151-44710714 Disease related genes, Predicted secreted proteins Evidence at protein level HPA045075 Uncertain Not detected Not detected tonsil: 0.5 Cell line enhanced U-266/70: 1.1 +SLC23A3 FLJ31168, SVCT3, Yspl1 ENSG00000213901 Solute carrier family 23 member 3 2 219161465-219170095 Predicted membrane proteins, Transporters Evidence at protein level HPA019059 Approved Nucleus
Cell Junctions Tissue enriched Tissue enhanced kidney: 53.1;small intestine: 22.9 duodenum: 8.7 Cell line enhanced hTCEpi: 3.5 +LTB4R BLTR, CMKRL1, GPR16, LTB4R1, P2RY7, P2Y7 ENSG00000213903 Leukotriene B4 receptor 14 24311450-24318036 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level HPA003873 Approved Renal cancer:3.44e-15 (unfavourable), Pancreatic cancer:1.85e-4 (favourable) Expressed in all Tissue enhanced skin: 165.8 esophagus: 42.6 Expressed in all +LTB4R2 BLT2, BLTR2, JULF2, NOP9 ENSG00000213906 Leukotriene B4 receptor 2 14 24305734-24312053 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB022689, HPA029680, HPA072921 Uncertain Supported Nucleoplasm
Plasma membrane Mixed Tissue enhanced skin: 40.5 spleen: 10.3 Cell line enhanced HaCaT: 24.8 +DNASE1 DNL1 ENSG00000213918 Deoxyribonuclease 1 16 3611728-3680143 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA010703 Enhanced Supported Vesicles Urothelial cancer:1.14e-4 (favourable) Expressed in all Tissue enhanced small intestine: 37.8 duodenum: 29.9 Mixed +MDP1 FN6Pase, MGC5987 ENSG00000213920 Magnesium dependent phosphatase 1 14 24213937-24216070 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003064, HPA070338 Uncertain Approved Nucleoplasm Renal cancer:5.96e-4 (favourable) Expressed in all Expressed in all thyroid gland: 20.3 Mixed +LEUTX ENSG00000213921 Leucine twenty homeobox 19 39776595-39786167 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA041498 Uncertain Approved Nucleus
Nucleoli Not detected Not detected all non-specific tissues: 0.0 Not detected +CSNK1E CKIE, CKIepsilon, HCKIE ENSG00000213923 Casein kinase 1 epsilon 22 38290691-38318084 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB009626, HPA026288 Approved Approved Nucleus
Cytosol Renal cancer:4.67e-6 (unfavourable), Liver cancer:8.20e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 171.1 Expressed in all +CCL27 ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine ENSG00000213927 C-C motif chemokine ligand 27 9 34661880-34664048 Predicted secreted proteins Evidence at protein level HPA073848 Enhanced Not detected Tissue enriched 16 skin: 504.4 breast: 32.2 Cell line enhanced AN3-CA: 2.0 +IRF9 ISGF3G ENSG00000213928 Interferon regulatory factor 9 14 24161053-24166565 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001862 Approved Supported Cytosol Renal cancer:7.58e-8 (unfavourable), Urothelial cancer:9.92e-4 (favourable) Expressed in all Expressed in all spleen: 94.1 Expressed in all +GALT ENSG00000213930 Galactose-1-phosphate uridylyltransferase 9 34638133-34651035 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004868, HPA005729 Enhanced Approved Cytosol Renal cancer:6.25e-6 (favourable), Pancreatic cancer:3.11e-5 (favourable) Expressed in all Expressed in all liver: 25.7 Mixed +HBE1 HBE ENSG00000213931 Hemoglobin subunit epsilon 1 11 5268345-5505617 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043234 Approved Approved Vesicles Mixed Tissue enhanced testis: 1.0 placenta: 0.9 Cell line enriched 15 K-562: 5976.4 +HBG1 HBG-T2 ENSG00000213934 Hemoglobin subunit gamma 1 11 5248083-5249892 Predicted intracellular proteins Evidence at protein level HPA043234 Approved Approved Vesicles Not detected Tissue enriched 66 placenta: 1087.7 bone marrow: 16.4 Group enriched 298 HEL: 988.4;K-562: 1948.2 +CLDN9 ENSG00000213937 Claudin 9 16 3012456-3014505 Predicted membrane proteins Evidence at protein level HPA076613 Supported Vesicles
Cell Junctions Endometrial cancer:2.24e-6 (unfavourable), Stomach cancer:4.67e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 3.2 bone marrow: 1.7 Cell line enhanced CAPAN-2: 5.5;MCF7: 16.8;SCLC-21H: 19.5 +ITGA1 CD49a, VLA1 ENSG00000213949 Integrin subunit alpha 1 5 52787896-52959210 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA042555 Uncertain Renal cancer:2.24e-4 (unfavourable) Expressed in all Mixed spleen: 78.0 Cell line enhanced fHDF/TERT166: 28.9;HHSteC: 36.5;WM-115: 32.9 +NUDT19 RP2 ENSG00000213965 Nudix hydrolase 19 19 32691961-32713796 Predicted secreted proteins Evidence at protein level HPA042761 Uncertain Nucleus
Nucleoli
Cytosol Urothelial cancer:1.35e-4 (favourable) Expressed in all Expressed in all prostate: 12.2 Mixed +ZNF726 ENSG00000213967 Zinc finger protein 726 19 23914876-23945159 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Mixed epididymis: 6.3 Mixed +ZNF99 C19orf9, MGC24986 ENSG00000213973 Zinc finger protein 99 19 22752183-22784107 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enriched Tissue enriched 7 testis: 3.0 cerebral cortex: 0.4 Not detected +TAX1BP3 TIP-1 ENSG00000213977 Tax1 binding protein 3 17 3662896-3668682 Predicted intracellular proteins Evidence at protein level HPA046410, HPA063078 Approved Approved Nucleoli fibrillar center
Vesicles
Actin filaments Glioma:1.66e-4 (unfavourable), Lung cancer:1.76e-4 (unfavourable), Renal cancer:7.90e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 228.1 Expressed in all +AP1G2 G2AD ENSG00000213983 Adaptor related protein complex 1 gamma 2 subunit 14 23559565-23568070 Predicted intracellular proteins Evidence at protein level HPA004106 Approved Renal cancer:1.79e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 59.5 Cell line enhanced RT4: 119.1 +ZNF90 HTF9 ENSG00000213988 Zinc finger protein 90 19 20077994-20127076 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003227 Uncertain Approved Nucleus
Golgi apparatus Tissue enhanced Tissue enhanced parathyroid gland: 7.6 thyroid gland: 2.7 Cell line enhanced AN3-CA: 9.0;NTERA-2: 16.5 +NAXD CARKD, FLJ10769, LP3298 ENSG00000213995 NAD(P)HX dehydratase 13 110615460-110639993 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010551 Uncertain Renal cancer:4.63e-5 (favourable), Endometrial cancer:3.15e-4 (favourable) Expressed in all Expressed in all adrenal gland: 26.9 Mixed +TM6SF2 Lpr4 ENSG00000213996 Transmembrane 6 superfamily member 2 19 19264364-19273391 Predicted membrane proteins Evidence at protein level HPA066026 Uncertain Tissue enhanced Group enriched 5 duodenum: 77.0;small intestine: 76.8 liver: 14.7 Cell line enhanced HHSteC: 1.6;LHCN-M2: 1.2;SH-SY5Y: 1.8 +MEF2B RSRFR2 ENSG00000213999 Myocyte enhancer factor 2B 19 19145568-19170289 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004734 Supported Not detected Group enriched 9 appendix: 17.6;lymph node: 45.7;tonsil: 27.2 spleen: 3.2 Group enriched 12 Daudi: 157.3;U-266/70: 161.9;U-698: 199.1 +GANC ENSG00000214013 Glucosidase alpha, neutral C 15 42273233-42356935 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA016949 Approved Approved Nucleoplasm
Actin filaments Lung cancer:9.76e-4 (favourable) Expressed in all Expressed in all lung: 29.8 Expressed in all +TTLL3 DKFZP434B103, HOTTL ENSG00000214021 Tubulin tyrosine ligase like 3 3 9808086-9855138 Predicted intracellular proteins Evidence at protein level HPA051413 Approved Renal cancer:6.45e-6 (unfavourable), Urothelial cancer:9.51e-6 (favourable) Mixed Expressed in all testis: 52.5 Cell line enhanced BEWO: 59.9 +REPIN1 AP4, H_DJ0584D14.12, RIP60, Zfp464, ZNF464 ENSG00000214022 Replication initiator 1 7 150368189-150374044 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036022 Approved Enhanced Nucleus Pancreatic cancer:1.12e-4 (favourable), Stomach cancer:1.61e-4 (favourable), Renal cancer:5.56e-4 (favourable), Urothelial cancer:6.41e-4 (favourable) Expressed in all Expressed in all spleen: 48.3 Expressed in all +MRPL23 L23MRP, RPL23L ENSG00000214026 Mitochondrial ribosomal protein L23 11 1947278-1984522 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050406 Approved Supported Nucleoli fibrillar center
Mitochondria Endometrial cancer:3.97e-4 (favourable) Expressed in all Expressed in all fallopian tube: 89.5 Cell line enhanced HEK 293: 573.2 +ZNF891 ENSG00000214029 Zinc finger protein 891 12 133106817-133130473 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA040301 Uncertain Mixed Mixed testis: 2.1 Mixed +IFNA7 IFN-alphaJ, IFNA-J ENSG00000214042 Interferon alpha 7 9 21201469-21202205 Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +SMIM7 C19orf42, MGC2747 ENSG00000214046 Small integral membrane protein 7 19 16630751-16660442 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA043127 Uncertain Approved Golgi apparatus Expressed in all Expressed in all epididymis: 55.4 Expressed in all +FBXO16 FBX16 ENSG00000214050 F-box protein 16 8 28348287-28490318 Predicted intracellular proteins Evidence at transcript level HPA053955, HPA058676 Uncertain Approved Nucleoplasm
Vesicles
Plasma membrane
Cytosol Ovarian cancer:6.70e-5 (favourable) Mixed Tissue enhanced epididymis: 22.4 thyroid gland: 12.1 Cell line enhanced AF22: 19.5 +TSPAN4 NAG-2, TETRASPAN, TM4SF7, TSPAN-4 ENSG00000214063 Tetraspanin 4 11 842808-867116 Predicted membrane proteins Evidence at protein level Liver cancer:1.02e-4 (unfavourable), Glioma:2.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 105.4 Expressed in all +CPNE1 CPN1 ENSG00000214078 Copine 1 20 35626031-35664956 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047259, HPA072634 Approved Approved Nucleoplasm
Nuclear membrane Renal cancer:2.74e-10 (unfavourable) Expressed in all Expressed in all smooth muscle: 104.0 Expressed in all +ARL16 ENSG00000214087 ADP ribosylation factor like GTPase 16 17 81681174-81683924 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043711 Uncertain Expressed in all Expressed in all cerebral cortex: 37.8 Expressed in all +SMCO1 C3orf43, DKFZp313B0440, FLJ41923 ENSG00000214097 Single-pass membrane protein with coiled-coil domains 1 3 196506877-196515366 Predicted intracellular proteins Evidence at transcript level HPA061937 Uncertain Not detected Group enriched 15 heart muscle: 24.2;skeletal muscle: 51.1 esophagus: 2.5 Not detected +WEE2 FLJ16107 ENSG00000214102 WEE1 homolog 2 7 141708353-141731271 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027418 Uncertain Supported Nucleoplasm
Cytosol Not detected Not detected skin,thyroid gland: 0.8 Cell line enhanced CACO-2: 2.6 +MAGEB1 CT3.1, DAM10, MAGE-Xp, MAGEL1, MGC9322 ENSG00000214107 MAGE family member B1 X 30243730-30252038 Predicted intracellular proteins Evidence at protein level HPA001193, HPA002820 Enhanced Tissue enriched Tissue enriched 45 testis: 29.2 epididymis: 0.6 Group enriched 58 K-562: 22.4;U-266/70: 41.0;U-266/84: 28.1 +LYRM4 C6orf149, CGI-203, ISD11 ENSG00000214113 LYR motif containing 4 6 5102593-5260939 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030362 Approved Supported Nuclear bodies Expressed in all Expressed in all ovary: 29.5 Expressed in all +MYCBP AMY-1 ENSG00000214114 MYC binding protein 1 38862964-38874105 Predicted intracellular proteins Evidence at protein level HPA041188 Supported Liver cancer:6.03e-6 (unfavourable) Expressed in all Expressed in all fallopian tube: 38.8 Expressed in all +TMEM213 ENSG00000214128 Transmembrane protein 213 7 138797952-138838101 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054059 Enhanced Renal cancer:5.54e-7 (favourable) Tissue enriched Group enriched 9 kidney: 80.7;salivary gland: 22.6 breast: 5.7 Not detected +PRCD RP36 ENSG00000214140 Photoreceptor disc component 17 76527586-76553578 Disease related genes, Predicted secreted proteins Evidence at protein level Mixed Mixed parathyroid gland: 3.1 Cell line enhanced BEWO: 1.4;Hep G2: 1.5;HHSteC: 1.1;HSkMC: 1.2;SH-SY5Y: 1.4 +ALG3 CDGS4, D16Ertd36e, Not56, NOT56L ENSG00000214160 ALG3, alpha-1,3- mannosyltransferase 3 184242301-184249548 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA045103 Approved Liver cancer:1.58e-5 (unfavourable), Lung cancer:8.67e-5 (unfavourable), Renal cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.4 Expressed in all +ZNF788 FLJ46419 ENSG00000214189 Zinc finger family member 788 19 12092263-12137235 Predicted intracellular proteins Evidence at transcript level Mixed Mixed testis: 5.6 Cell line enhanced K-562: 20.7;NTERA-2: 20.5 +SH3D21 C1orf113, FLJ22938 ENSG00000214193 SH3 domain containing 21 1 36306387-36324886 Predicted intracellular proteins Evidence at protein level HPA042212, HPA042456, HPA066168 Approved Approved Nucleus
Plasma membrane Renal cancer:1.76e-6 (unfavourable), Breast cancer:2.60e-4 (favourable) Mixed Tissue enhanced small intestine: 22.2 skin: 15.5 Cell line enhanced HaCaT: 15.2 +LINC00998 ENSG00000214194 Long intergenic non-protein coding RNA 998 7 113116718-113118613 Predicted membrane proteins Evidence at transcript level Liver cancer:1.02e-4 (unfavourable), Renal cancer:7.21e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 123.3 Mixed +C19orf38 HIDE1 ENSG00000214212 Chromosome 19 open reading frame 38 19 10836575-10869790 Predicted membrane proteins Evidence at protein level HPA012150, HPA055027 Uncertain Golgi apparatus
Plasma membrane
Cytosol Renal cancer:1.75e-7 (unfavourable), Cervical cancer:2.43e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 62.8 spleen: 17.4 Cell line enhanced U-937: 39.3 +C12orf74 ENSG00000214215 Chromosome 12 open reading frame 74 12 92702843-92708549 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced fallopian tube: 1.9 cervix, uterine,urinary bladder: 0.8 Not detected +IQCJ ENSG00000214216 IQ motif containing J 3 158962928-159266307 Predicted intracellular proteins Evidence at transcript level HPA052835 Uncertain Not detected Not detected testis: 0.9 Cell line enriched 17 Daudi: 3.7 +C17orf67 ENSG00000214226 Chromosome 17 open reading frame 67 17 56791913-56838773 Predicted secreted proteins Evidence at protein level HPA043479 Uncertain Approved Mixed Mixed spleen: 3.7 Cell line enhanced MOLT-4: 11.9 +MINDY4B C3orf76, FAM188B2 ENSG00000214237 MINDY family member 4B 3 150871045-150905439 Predicted intracellular proteins No evidence Not detected Not detected endometrium: 0.6 Not detected +FIS1 CGI-135, Fis1, H_NH0132A01.6, TTC11 ENSG00000214253 Fission, mitochondrial 1 7 101239458-101252316 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017430 Approved Enhanced Mitochondria Renal cancer:1.08e-7 (favourable) Expressed in all Expressed in all thyroid gland: 269.9 Expressed in all +ANG RAA1, RNASE5 ENSG00000214274 Angiogenin 14 20684177-20698971 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Liver cancer:7.83e-5 (favourable), Endometrial cancer:6.85e-4 (favourable) Tissue enriched Tissue enriched 27 liver: 1565.4 stomach: 57.0 Cell line enriched 5 Hep G2: 105.0 +SCART1 ENSG00000214279 Scavenger receptor protein family member 10 133453928-133523558 Predicted membrane proteins Evidence at protein level HPA043101 Supported Not detected Not detected endometrium: 0.2 Cell line enhanced HMC-1: 3.4;NB-4: 2.3;U-266/84: 2.8 +NPS ENSG00000214285 Neuropeptide S 10 127549369-127552639 Predicted secreted proteins No evidence CAB020139 Uncertain Tissue enriched Not detected all non-specific tissues: 0.0 Not detected +COLCA2 C11orf93, CASC13 ENSG00000214290 Colorectal cancer associated 2 11 111298555-111308735 Predicted intracellular proteins Evidence at transcript level Renal cancer:8.97e-6 (favourable) Mixed Mixed epididymis: 33.1 Cell line enhanced HaCaT: 4.7;Hep G2: 7.8;RT4: 8.4;T-47d: 5.3 +SPDYE3 ENSG00000214300 Speedy/RINGO cell cycle regulator family member E3 7 100307702-100322196 Predicted intracellular proteins Evidence at protein level HPA051750 Supported Endometrial cancer:2.00e-6 (unfavourable), Breast cancer:8.73e-4 (favourable) Expressed in all Tissue enriched 11 testis: 2.3 skin: 0.2 Not detected +MBLAC1 MGC49416 ENSG00000214309 Metallo-beta-lactamase domain containing 1 7 100126694-100128498 Predicted intracellular proteins Evidence at protein level HPA071574 Uncertain Renal cancer:7.90e-5 (favourable), Pancreatic cancer:1.18e-4 (favourable) Expressed in all Mixed cerebral cortex: 3.9 Mixed +FOXI3 ENSG00000214336 Forkhead box I3 2 88446787-88452656 Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enhanced Tissue enriched 9 placenta: 7.4 testis: 0.8 Cell line enhanced BEWO: 42.3;HAP1: 6.2;NTERA-2: 11.0 +SOGA3 C6orf174, dJ403A15.3 ENSG00000214338 SOGA family member 3 6 127472794-127519191 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035388, HPA035389 Uncertain Approved Nucleus
Cytosol Not detected Tissue enriched 7 cerebral cortex: 10.1 ovary,stomach: 1.5 Cell line enhanced SCLC-21H: 36.7;SH-SY5Y: 18.9 +NEURL1B DKFZP761M1511, Neur2 ENSG00000214357 Neuralized E3 ubiquitin protein ligase 1B 5 172641266-172691540 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037612 Approved Supported Vesicles Renal cancer:3.00e-6 (unfavourable) Expressed in all Mixed seminal vesicle: 45.0 Cell line enhanced REH: 39.9 +EFCAB9 ENSG00000214360 EF-hand calcium binding domain 9 5 172194172-172203452 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 97 testis: 15.7 appendix,gallbladder: 0.1 Cell line enhanced WM-115: 1.5 +HAUS3 C4orf15, dgt3, IT1, MGC4701 ENSG00000214367 HAUS augmin like complex subunit 3 4 2227464-2242164 Predicted intracellular proteins Evidence at protein level HPA040649, HPA048190 Approved Approved Microtubules
Cytokinetic bridge
Mitotic spindle
Mitochondria Urothelial cancer:4.78e-5 (favourable) Expressed in all Expressed in all bone marrow: 31.8 Expressed in all +VSTM5 C11orf90, LOC387804 ENSG00000214376 V-set and transmembrane domain containing 5 11 93818232-93850531 Predicted membrane proteins Evidence at transcript level HPA029525, HPA063591 Uncertain Uncertain Endoplasmic reticulum Mixed Tissue enhanced placenta: 6.5 cerebral cortex: 2.8 Cell line enhanced HaCaT: 1.1;PC-3: 5.1;SH-SY5Y: 2.3 +LCNL1 FLJ45224 ENSG00000214402 Lipocalin like 1 9 136981904-136986410 Predicted intracellular proteins Evidence at transcript level Mixed Not detected seminal vesicle: 0.7 Not detected +BBIP1 bA348N5.3, BBIP10, BBS18, NCRNA00081 ENSG00000214413 BBSome interacting protein 1 10 110898730-110919274 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055206 Uncertain Expressed in all Expressed in all testis: 180.8 Expressed in all +TRIM77 TRIM77P ENSG00000214414 Tripartite motif containing 77 11 89710299-89717872 Predicted intracellular proteins Evidence at transcript level HPA039896 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +GNAT3 GDCA, gustducin ENSG00000214415 G protein subunit alpha transducin 3 7 80458671-80512020 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enhanced duodenum: 1.9;small intestine: 1.4 testis: 0.5 Cell line enriched 8 SCLC-21H: 3.9 +AS3MT CYT19 ENSG00000214435 Arsenite methyltransferase 10 102869516-102901899 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017856 Enhanced Approved Nucleus
Mitochondria Tissue enhanced Group enriched 6 adrenal gland: 251.5;parathyroid gland: 119.3 liver: 30.4 Cell line enhanced REH: 50.0;SH-SY5Y: 29.9;T-47d: 41.6 +FAM187A ENSG00000214447 Family with sequence similarity 187 member A 17 44899712-44905390 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA022794, HPA043131 Approved Approved Cytosol Not detected Tissue enhanced fallopian tube: 24.6;testis: 17.2 thyroid gland: 5.3 Cell line enhanced U-87 MG: 12.7 +PLIN5 LSDA5, LSDP5, MLDP, OXPAT ENSG00000214456 Perilipin 5 19 4522531-4535224 Predicted intracellular proteins Evidence at protein level Renal cancer:1.97e-4 (favourable), Urothelial cancer:2.16e-4 (favourable), Liver cancer:2.81e-4 (favourable), Breast cancer:7.68e-4 (favourable), Endometrial cancer:8.56e-4 (unfavourable) Tissue enhanced Tissue enhanced adipose tissue: 34.5;ovary: 42.4 salivary gland: 25.8 Cell line enhanced BEWO: 3.2;SH-SY5Y: 3.0;T-47d: 5.9 +SEC14L6 ENSG00000214491 SEC14 like lipid binding 6 22 30522799-30546682 Predicted intracellular proteins Evidence at transcript level HPA067695 Approved Nucleoplasm Tissue enriched Tissue enhanced epididymis: 25.8;parathyroid gland: 46.1 lung: 17.8 Cell line enhanced K-562: 11.1;RPTEC TERT1: 16.7;SiHa: 7.0 +SPINK13 HESPINTOR, LiESP6, MGC149260, SPINK5L3 ENSG00000214510 Serine peptidase inhibitor, Kazal type 13 (putative) 5 148268180-148286254 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA036456 Uncertain Approved Nucleus
Plasma membrane Renal cancer:4.03e-10 (unfavourable) Group enriched Tissue enriched 8 epididymis: 309.7 seminal vesicle: 37.3 Cell line enriched 13 HeLa: 304.5 +HIGD1C Gm921 ENSG00000214511 HIG1 hypoxia inducible domain family member 1C 12 50953922-50970506 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced testis: 2.9 parathyroid gland: 2.1 Cell line enhanced BEWO: 1.2;Karpas-707: 1.1 +NOTO ENSG00000214513 Notochord homeobox 2 73202258-73212513 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA034660 Uncertain Not detected Not detected skin: 0.4 Not detected +PPME1 PME-1 ENSG00000214517 Protein phosphatase methylesterase 1 11 74171099-74254703 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004541, HPA043900, HPA064396 Uncertain Supported Nucleus
Nuclear bodies Liver cancer:4.45e-6 (unfavourable), Renal cancer:2.76e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 156.1 Expressed in all +KRTAP2-2 KAP2.2 ENSG00000214518 Keratin associated protein 2-2 17 41054498-41055230 Predicted intracellular proteins Evidence at protein level HPA059203 Supported Not detected Not detected all non-specific tissues: 0.0 Not detected +STARD10 CGI-52, NY-CO-28, PCTP2, SDCCAG28 ENSG00000214530 StAR related lipid transfer domain containing 10 11 72754729-72794168 Predicted intracellular proteins Evidence at protein level HPA026661 Uncertain Breast cancer:6.92e-4 (favourable) Expressed in all Expressed in all rectum: 205.1 Expressed in all +ZNF705E ENSG00000214534 Zinc finger protein 705E 11 71814045-71821548 Predicted intracellular proteins No evidence Not detected Not detected epididymis: 0.6 Not detected +NUTM2D FAM22D ENSG00000214562 NUT family member 2D 10 87357668-87370695 Predicted intracellular proteins Evidence at transcript level Not detected Mixed cerebral cortex: 7.1 Mixed +CPEB1 CPEB, FLJ13203 ENSG00000214575 Cytoplasmic polyadenylation element binding protein 1 15 82543201-82648861 Predicted intracellular proteins Evidence at protein level HPA040396 Supported Nucleoplasm
Cytosol Tissue enriched Tissue enhanced testis: 61.1 cerebral cortex: 22.3 Cell line enhanced SK-MEL-30: 29.5;U-2197: 103.8;U-87 MG: 39.3 +EML6 FLJ42562 ENSG00000214595 Echinoderm microtubule associated protein like 6 2 54723499-54972025 Predicted intracellular proteins Evidence at protein level HPA062808, HPA068759 Uncertain Approved Vesicles
Mitochondria Mixed Tissue enhanced lymph node: 7.5;tonsil: 8.3 appendix: 4.4 Cell line enhanced SCLC-21H: 32.4;U-698: 22.3 +DEFB113 DEFB-13 ENSG00000214642 Defensin beta 113 6 49968677-49969625 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 568 epididymis: 56.8 all non-specific tissues: 0.0 Not detected +DEFB133 ENSG00000214643 Defensin beta 133 6 49946021-49950265 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 158 epididymis: 15.7 all non-specific tissues: 0.0 Not detected +ZNF727 ZNF727P ENSG00000214652 Zinc finger protein 727 7 64045443-64078549 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051027, HPA061215 Uncertain Uncertain Nucleoplasm Tissue enhanced Mixed thyroid gland: 5.8 Cell line enriched 7 T-47d: 7.1 +RP11-27I1.4 ENSG00000214654 Putative UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase LOC100288842 9 120793551-120799918 Predicted intracellular proteins Evidence at transcript level Expressed in all Mixed thyroid gland: 5.0 Mixed +ZSWIM8 4832404P21Rik, KIAA0913 ENSG00000214655 Zinc finger SWIM-type containing 8 10 73785582-73801797 Predicted intracellular proteins Evidence at protein level HPA041244 Approved Approved Plasma membrane
Cytosol Head and neck cancer:5.61e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 63.2 Expressed in all +IQCF5 ENSG00000214681 IQ motif containing F5 3 51873721-51875584 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 708 testis: 70.8 all non-specific tissues: 0.0 Not detected +IQCF6 ENSG00000214686 IQ motif containing F6 3 51778561-51779187 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 125 testis: 17.6 kidney,skin,stomach: 0.1 Cell line enhanced U-937: 1.1 +C10orf105 FLJ00245 ENSG00000214688 Chromosome 10 open reading frame 105 10 71711702-71737824 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enhanced cerebral cortex: 2.3;spleen: 3.2 testis: 1.4 Cell line enriched 6 BJ hTERT+: 2.6 +ARHGEF33 ENSG00000214694 Rho guanine nucleotide exchange factor 33 2 38889880-38975449 Predicted intracellular proteins Evidence at protein level HPA034661, HPA041051 Enhanced Supported Vesicles Mixed Tissue enhanced testis: 10.6 ovary: 4.3 Cell line enhanced BEWO: 5.4;SiHa: 7.6 +C12orf71 LOC728858 ENSG00000214700 Chromosome 12 open reading frame 71 12 27081058-27082514 Predicted intracellular proteins Evidence at transcript level HPA058728 Uncertain Not detected Tissue enhanced testis: 4.8 skin: 1.0 Cell line enhanced HDLM-2: 1.4 +IFRD2 IFNRP, SKMc15, SM15 ENSG00000214706 Interferon related developmental regulator 2 3 50287732-50292918 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA068560 Approved Approved Nucleoplasm Renal cancer:2.50e-4 (favourable), Breast cancer:7.22e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 28.9 Expressed in all +CAPN14 ENSG00000214711 Calpain 14 2 31173056-31233858 Enzymes, Predicted intracellular proteins Evidence at protein level Group enriched Tissue enriched 26 esophagus: 88.2 tonsil: 3.3 Cell line enhanced U-266/70: 2.1 +ZBED1 ALTE, DREF, hDREF, KIAA0785, TRAMP ENSG00000214717 Zinc finger BED-type containing 1 X 2486414-2500967 Predicted intracellular proteins, Transcription factors Evidence at protein level Renal cancer:3.13e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 24.6 Cell line enhanced BEWO: 87.7 +RP1-139D8.6 ENSG00000214732 6 42155426-42163439 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 363 testis: 67.8 cervix, uterine,esophagus: 0.1 Not detected +TOMM6 OBTP, Tom6 ENSG00000214736 Translocase of outer mitochondrial membrane 6 6 41787662-41789898 Predicted intracellular proteins Evidence at protein level HPA004801 Approved Supported Mitochondria Not detected Expressed in all epididymis: 322.2 Expressed in all +HNRNPUL2 DKFZp762N1910, HNRPUL2 ENSG00000214753 Heterogeneous nuclear ribonucleoprotein U like 2 11 62712630-62727349 Predicted intracellular proteins Evidence at protein level HPA041632, HPA056696, HPA067699 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all cerebral cortex: 59.2 Expressed in all +METTL12 U99HG ENSG00000214756 Methyltransferase like 12 11 62665309-62668496 Predicted intracellular proteins Evidence at transcript level HPA038115, HPA038533 Uncertain Breast cancer:8.73e-4 (favourable) Expressed in all Not detected fallopian tube: 0.8 Mixed +RP11-726G1.1 ENSG00000214776 12 9467552-9576275 Predicted secreted proteins Evidence at transcript level Group enriched Tissue enhanced parathyroid gland: 1.0;testis: 1.8 endometrium,lymph node: 0.4 Cell line enhanced U-698: 4.3;WM-115: 2.1 +MS4A18 ENSG00000214782 Membrane spanning 4-domains A18 11 60729304-60744212 Predicted membrane proteins Evidence at transcript level HPA045121 Approved Not detected Tissue enhanced breast: 10.3;duodenum: 23.9 small intestine: 4.0 Not detected +MS4A4E ENSG00000214787 Membrane spanning 4-domains A4E 11 60201253-60243088 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040075 Uncertain Mixed Mixed adipose tissue: 5.9 Cell line enhanced K-562: 1.9;THP-1: 2.0 +FER1L6 C8ORFK23 ENSG00000214814 Fer-1 like family member 6 8 123851987-124120061 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA054117 Uncertain Group enriched Group enriched 5 rectum: 12.0;stomach: 42.4 small intestine: 5.1 Cell line enhanced AF22: 1.0;ASC TERT1: 1.3;BJ hTERT+: 1.0;PC-3: 1.6;U-87 MG: 1.6 +CDRT15L2 ENSG00000214819 CMT1A duplicated region transcript 15-like 2 17 20579724-20580911 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 11 testis: 13.2 epididymis: 1.2 Not detected +MTCP1 P13MTCP1, p8MTCP1 ENSG00000214827 Mature T-cell proliferation 1 X 155061622-155147937 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA032040 Approved Nucleoplasm
Plasma membrane Renal cancer:4.52e-8 (unfavourable) Mixed Mixed testis: 8.7 Mixed +RAD51AP2 FLJ17540 ENSG00000214842 RAD51 associated protein 2 2 17510584-17518439 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 39 testis: 16.9 cerebral cortex: 0.4 Not detected +EVPLL ENSG00000214860 Envoplakin like 17 18377662-18389647 Predicted intracellular proteins Evidence at transcript level HPA045728 Uncertain Approved Nucleoplasm
Nuclear bodies Not detected Tissue enhanced esophagus: 1.7;skin: 3.0;testis: 1.5 lung: 0.8 Cell line enhanced HeLa: 1.2;hTCEpi: 4.7;RT4: 1.8;SiHa: 1.3;T-47d: 1.9 +DCDC2C ENSG00000214866 Doublecortin domain containing 2C 2 3703592-3847411 Predicted intracellular proteins Evidence at transcript level HPA045848 Uncertain Not detected Tissue enriched 40 testis: 5.9 fallopian tube,prostate: 0.1 Not detected +SMTNL1 CHASM ENSG00000214872 Smoothelin like 1 11 57542641-57550274 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 26 skeletal muscle: 240.9 esophagus: 9.3 Cell line enhanced U-266/70: 1.2 +TRIM64C ENSG00000214891 Tripartite motif containing 64C 11 49053714-49059112 Predicted intracellular proteins No evidence HPA045370 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +U82695.5 ENSG00000214897 X 153395640-153401420 Predicted intracellular proteins Evidence at transcript level Mixed Group enriched 35 epididymis: 5.8;ovary: 4.7;testis: 10.9 fallopian tube: 0.2 Not detected +SPATA31D1 FAM75D1, FLJ46321 ENSG00000214929 SPATA31 subfamily D member 1 9 81988772-81995256 Predicted membrane proteins Evidence at transcript level HPA047897 Uncertain Not detected Tissue enriched 100 testis: 9.9 all non-specific tissues: 0.0 Not detected +NPIPA8 LCR16a9 ENSG00000214940 Nuclear pore complex interacting protein family member A8 16 18317942-18336736 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Not detected Mixed cerebral cortex: 21.8 Cell line enhanced EFO-21: 55.7;HMC-1: 196.9;SCLC-21H: 63.6 +ZSWIM7 SWS1 ENSG00000214941 Zinc finger SWIM-type containing 7 17 15976560-15999717 Predicted intracellular proteins Evidence at protein level HPA054681 Uncertain Uncertain Cytosol Endometrial cancer:3.54e-5 (favourable), Pancreatic cancer:1.77e-4 (favourable) Expressed in all Mixed cerebral cortex: 11.9 Expressed in all +GPR33 ENSG00000214943 G protein-coupled receptor 33 (gene/pseudogene) 14 31482875-31488142 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected spleen: 0.3 Not detected +ARHGEF28 p190RhoGEF, RGNEF, RIP2 ENSG00000214944 Rho guanine nucleotide exchange factor 28 5 73626158-73941993 Predicted intracellular proteins Evidence at protein level HPA037602 Enhanced Approved Plasma membrane
Microtubules
Cytosol Renal cancer:1.91e-6 (favourable), Cervical cancer:5.31e-4 (favourable), Urothelial cancer:8.98e-4 (favourable) Mixed Mixed kidney: 33.7 Cell line enhanced hTERT-HME1: 75.2;LHCN-M2: 76.8;TIME: 48.7 +TBC1D26 MGC51025 ENSG00000214946 TBC1 domain family member 26 17 15732247-15749192 Predicted intracellular proteins Evidence at transcript level HPA050460 Uncertain Not detected Tissue enriched 68 testis: 16.4 breast,cerebral cortex,lung,parathyroid gland,skin: 0.2 Cell line enhanced U-698: 1.0 +LRRC69 ENSG00000214954 Leucine rich repeat containing 69 8 91101832-91219236 Predicted intracellular proteins Evidence at transcript level HPA046337 Uncertain Approved Plasma membrane Mixed Tissue enhanced testis: 5.2 skin: 2.0 Cell line enhanced HEK 293: 5.7;U-266/70: 12.2;U-266/84: 6.6 +ISPD hCG_1745121, IspD, Nip ENSG00000214960 Isoprenoid synthase domain containing 7 16087527-16421322 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043810, HPA053554 Approved Approved Nucleus
Nucleoli fibrillar center Renal cancer:1.38e-11 (favourable) Mixed Mixed cerebral cortex: 3.5 Cell line enhanced HEL: 6.9 +NPIPA7 ENSG00000214967 Nuclear pore complex interacting protein family member A7 16 16379055-16393954 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Not detected Expressed in all parathyroid gland: 48.8 Expressed in all +GSG1L2 ENSG00000214978 GSG1 like 2 17 9802386-9822071 Predicted membrane proteins Evidence at transcript level HPA059428 Uncertain Tissue enriched Group enriched 13 cerebral cortex: 1.5;testis: 1.0 all non-specific tissues: 0.0 Not detected +ACSM4 ENSG00000215009 Acyl-CoA synthetase medium-chain family member 4 12 7304284-7328724 Enzymes, Predicted membrane proteins Evidence at transcript level HPA049895 Uncertain Not detected Tissue enhanced testis: 1.7 spleen: 0.7 Cell line enhanced HDLM-2: 1.6;NB-4: 1.1;SH-SY5Y: 2.2;U-87 MG: 2.8 +C22orf29 BOP, FLJ21125 ENSG00000215012 Chromosome 22 open reading frame 29 22 19846138-19854896 Predicted intracellular proteins Evidence at protein level HPA000721, HPA001419 Uncertain Liver cancer:8.04e-5 (unfavourable) Expressed in all Mixed skin: 15.9 Expressed in all +COL28A1 ENSG00000215018 Collagen type XXVIII alpha 1 chain 7 7356203-7535853 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043844, HPA060468 Uncertain Approved Nucleoplasm
Cytosol Tissue enhanced Tissue enhanced epididymis: 18.2 fallopian tube: 8.0 Cell line enhanced U-266/70: 7.6;WM-115: 4.8 +PHB2 Bap37, BCAP37, p22, REA ENSG00000215021 Prohibitin 2 12 6965327-6970825 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB014889, CAB026335, HPA039874 Supported Enhanced Mitochondria Endometrial cancer:3.80e-4 (unfavourable) Expressed in all Expressed in all ovary: 269.3 Expressed in all +TCP11X2 ENSG00000215029 T-complex 11 family, X-linked 2 X 102374628-102471812 Predicted intracellular proteins Evidence at protein level HPA048311 Supported Not detected Tissue enhanced testis: 1.5 fallopian tube: 0.9 Cell line enriched 6 SCLC-21H: 1.2 +NEURL4 KIAA1787 ENSG00000215041 Neuralized E3 ubiquitin protein ligase 4 17 7315628-7329393 Predicted intracellular proteins Evidence at protein level HPA043678, HPA055314 Uncertain Pancreatic cancer:2.34e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 18.9 Expressed in all +GRID2IP ENSG00000215045 Grid2 interacting protein 7 6497462-6551436 Predicted intracellular proteins Evidence at protein level HPA045381 Uncertain Mixed Mixed parathyroid gland: 1.3 Cell line enhanced REH: 3.3 +CXorf49B ENSG00000215113 Chromosome X open reading frame 49B X 71763424-71767204 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 27 testis: 2.6 all non-specific tissues: 0.0 Cell line enriched 7 A-431: 8.0 +UBXN2B p37 ENSG00000215114 UBX domain protein 2B 8 58411264-58451501 Predicted intracellular proteins Evidence at protein level HPA045278 Uncertain Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 27.0 Expressed in all +CXorf49 ENSG00000215115 Chromosome X open reading frame 49 X 71714371-71718151 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 27 testis: 2.6 all non-specific tissues: 0.0 Cell line enriched 7 A-431: 8.0 +CBWD7 ENSG00000215126 COBW domain containing 7 9 41131306-41199261 Predicted intracellular proteins Evidence at transcript level HPA042759, HPA042813 Approved Approved Plasma membrane Not detected Tissue enhanced adrenal gland: 4.9 breast,seminal vesicle: 2.7 Cell line enhanced PC-3: 25.0 +C16orf90 LOC646174 ENSG00000215131 Chromosome 16 open reading frame 90 16 3493484-3495480 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 214 testis: 21.4 all non-specific tissues: 0.0 Not detected +PRSS41 TESSP1 ENSG00000215148 Protease, serine 41 16 2798485-2805302 Enzymes, Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enriched 6 testis: 1.6 stomach: 0.2 Cell line enriched 11 BEWO: 1.7 +NLRP2B CLRX.1, NALP2P, NLRP2P, NOD24, POP4 ENSG00000215174 NLR family pyrin domain containing 2B X 57677067-57680260 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +MUC5AC MUC5 ENSG00000215182 Mucin 5AC, oligomeric mucus/gel-forming 11 1157953-1201138 Predicted secreted proteins Evidence at protein level CAB002774, CAB009395, HPA040456, HPA040615 Enhanced Uncertain Vesicles Tissue enhanced Tissue enriched 61 stomach: 179.1 cervix, uterine: 2.9 Cell line enriched 18 A549: 18.0 +MSMP PC-3, PSMP ENSG00000215183 Microseminoprotein, prostate associated 9 35752990-35756613 Predicted intracellular proteins Evidence at protein level HPA055174 Uncertain Supported Vesicles
Cytosol Not detected Tissue enriched 5 placenta: 1.8 appendix: 0.3 Group enriched 8 HUVEC TERT2: 72.1;PC-3: 101.9 +GOLGA6B ENSG00000215186 Golgin A6 family member B 15 72654738-72666394 Predicted intracellular proteins Evidence at protein level HPA044978, HPA050087 Supported Not detected Group enriched 14 liver: 1.9;testis: 5.3 cerebral cortex: 0.2 Not detected +FAM166B ENSG00000215187 Family with sequence similarity 166 member B 9 35561831-35563899 Predicted intracellular proteins Evidence at protein level HPA045540 Enhanced Ovarian cancer:6.20e-6 (favourable), Endometrial cancer:2.61e-5 (favourable) Group enriched Group enriched 13 adrenal gland: 369.8;fallopian tube: 159.2;skeletal muscle: 82.6 epididymis: 16.2 Cell line enhanced Hep G2: 1.1 +PEX26 FLJ20695 ENSG00000215193 Peroxisomal biogenesis factor 26 22 18077920-18131138 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB070429 Approved Renal cancer:1.38e-4 (favourable), Liver cancer:3.10e-4 (unfavourable), Colorectal cancer:9.92e-4 (favourable) Expressed in all Expressed in all small intestine: 34.1 Expressed in all +GRXCR1 DFNB25, PPP1R88 ENSG00000215203 Glutaredoxin and cysteine rich domain containing 1 4 42893267-43030658 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040824 Uncertain Not detected Tissue enriched 8 seminal vesicle: 6.3 testis: 0.7 Not detected +C5orf49 LOC134121 ENSG00000215217 Chromosome 5 open reading frame 49 5 7830378-7851490 Predicted intracellular proteins Evidence at protein level HPA043759 Enhanced Tissue enhanced Group enriched 10 fallopian tube: 120.5;testis: 30.9 lung: 7.8 Not detected +UBE2QL1 FLJ25076 ENSG00000215218 Ubiquitin conjugating enzyme E2 Q family like 1 5 6448623-6494909 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA057414 Supported Nucleus
Plasma membrane Renal cancer:6.81e-8 (favourable) Mixed Tissue enhanced cerebral cortex: 41.8 seminal vesicle: 10.4 Cell line enhanced Karpas-707: 29.4;PC-3: 32.0;SCLC-21H: 37.2;U-266/70: 57.9;U-266/84: 50.5 +FASTKD5 FLJ13149 ENSG00000215251 FAST kinase domains 5 20 3146519-3159897 Predicted intracellular proteins Evidence at protein level HPA043833 Approved Renal cancer:8.19e-8 (favourable), Liver cancer:4.05e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 22.9 Expressed in all +GOLGA8B ENSG00000215252 Golgin A8 family member B 15 34525207-34588503 Predicted intracellular proteins Evidence at transcript level HPA051808 Approved Approved Golgi apparatus
Cytosol Renal cancer:9.38e-6 (unfavourable), Urothelial cancer:5.79e-4 (favourable) Expressed in all Tissue enhanced thyroid gland: 47.9 testis: 23.1 Cell line enhanced NB-4: 15.7 +KCNU1 KCa5.1, Kcnma3, KCNMC1, Slo3 ENSG00000215262 Potassium calcium-activated channel subfamily U member 1 8 36784324-36936128 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA063317 Uncertain Plasma membrane Tissue enhanced Tissue enriched 28 testis: 13.5 adipose tissue,epididymis: 0.4 Cell line enriched 6 HDLM-2: 7.3 +GAGE12G ENSG00000215269 G antigen 12G X 49570434-49577754 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Not detected Tissue enriched 78 stomach: 7.8 all non-specific tissues: 0.0 Cell line enriched 7 AN3-CA: 898.2 +HOMEZ KIAA1443 ENSG00000215271 Homeobox and leucine zipper encoding 14 23272422-23299447 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036316, HPA036317 Approved Supported Nucleus
Nucleoli Renal cancer:1.17e-11 (favourable), Ovarian cancer:2.41e-5 (favourable), Thyroid cancer:1.75e-4 (favourable) Expressed in all Expressed in all testis: 41.7 Expressed in all +GAGE10 ENSG00000215274 G antigen 10 X 49303669-49319844 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Not detected Tissue enhanced ovary: 1.1;testis: 1.4 fallopian tube: 0.7 Cell line enhanced AN3-CA: 2.3;WM-115: 1.0 +RNF212B C14orf164 ENSG00000215277 Ring finger protein 212B 14 23185316-23273477 Predicted intracellular proteins Evidence at transcript level HPA053574 Uncertain Not detected Group enriched 20 kidney: 27.7;testis: 10.4 thyroid gland: 0.9 Not detected +DDX3X DBX, DDX14, DDX3, HLP2 ENSG00000215301 DEAD-box helicase 3, X-linked X 41333348-41364472 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA001648, HPA005631, HPA059585 Supported Approved Approved Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland: 274.6 Expressed in all +VPS16 ENSG00000215305 VPS16, CORVET/HOPS core subunit 20 2840703-2866732 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043229, HPA048661 Approved Pancreatic cancer:5.89e-5 (favourable), Renal cancer:8.02e-5 (unfavourable), Liver cancer:1.43e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.5 Expressed in all +ZNF705D ENSG00000215343 Zinc finger protein 705D 8 12104389-12115516 Predicted intracellular proteins, Transcription factors Evidence at transcript level Not detected Tissue enriched 6 epididymis: 4.5 testis: 0.7 Not detected +ZNF705B ENSG00000215356 Zinc finger protein 705B 8 7926337-7952413 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 18 testis: 1.8 all non-specific tissues: 0.0 Not detected +ZNF705G ENSG00000215372 Zinc finger protein 705G 8 7355517-7385558 Predicted intracellular proteins, Transcription factors Evidence at transcript level Not detected Not detected testis: 0.9 Not detected +MYL5 ENSG00000215375 Myosin light chain 5 4 673580-682033 Predicted intracellular proteins Evidence at protein level HPA037381, HPA039262 Uncertain Approved Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 22.9 Expressed in all +SCRT2 ZNF898B ENSG00000215397 Scratch family transcriptional repressor 2 20 661596-676179 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA067697 Approved Nucleoplasm Tissue enriched Not detected cerebral cortex: 0.6 Group enriched 5 Karpas-707: 1.4;NTERA-2: 1.8;RPMI-8226: 2.8;SCLC-21H: 2.2;SH-SY5Y: 2.1 +ZNF407 FLJ13839, FLJ20307, KIAA1703 ENSG00000215421 Zinc finger protein 407 18 74597870-75065671 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028255, HPA041673 Uncertain Approved Nucleoplasm
Plasma membrane Renal cancer:9.79e-5 (favourable) Expressed in all Mixed parathyroid gland: 9.0 Mixed +NPEPL1 bA261P9.2, FLJ11583 ENSG00000215440 Aminopeptidase-like 1 20 58689131-58719238 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004986, CAB017025, HPA036356 Approved Approved Nucleoplasm Renal cancer:1.87e-9 (unfavourable), Urothelial cancer:5.73e-4 (favourable) Expressed in all Expressed in all spleen: 24.7 Cell line enhanced MCF7: 78.7 +KRTAP10-4 KAP10.4, KRTAP18-4, KRTAP18.4 ENSG00000215454 Keratin associated protein 10-4 21 44573724-44638284 Predicted intracellular proteins Evidence at protein level Not detected Not detected fallopian tube: 0.1 Not detected +KRTAP10-1 KAP10.1, KAP18.1, KRTAP18-1 ENSG00000215455 Keratin associated protein 10-1 21 44538981-44540195 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +RPL17-C18orf32 ENSG00000215472 RPL17-C18orf32 readthrough 18 49481681-49492479 Predicted intracellular proteins Evidence at protein level HPA043724, HPA046385 Approved Supported Endoplasmic reticulum
Cytosol Not detected Expressed in all cerebral cortex: 66.2 Mixed +SKOR2 CORL2, Fussel-18, FUSSEL18 ENSG00000215474 SKI family transcriptional corepressor 2 18 47206322-47251603 Predicted intracellular proteins Evidence at protein level HPA046206 Uncertain Not detected Not detected testis: 0.7 Cell line enhanced NTERA-2: 3.9 +SIAH3 FLJ39203 ENSG00000215475 Siah E3 ubiquitin protein ligase family member 3 13 45777243-45851736 Predicted intracellular proteins Evidence at transcript level HPA060576 Uncertain Tissue enhanced Tissue enhanced fallopian tube: 5.0 cerebral cortex,cervix, uterine: 1.4 Cell line enriched 8 EFO-21: 1.0 +EFCAB8 ENSG00000215529 EF-hand calcium binding domain 8 20 32858923-32961609 Predicted intracellular proteins Evidence at transcript level CAB034246, HPA042751 Uncertain Not detected Tissue enriched 6 testis: 2.8 appendix,small intestine,thyroid gland: 0.4 Not detected +DEFB116 DEFB-16 ENSG00000215545 Defensin beta 116 20 31303212-31308585 Predicted secreted proteins No evidence HPA047430 Uncertain Not detected Not detected epididymis: 0.6 Not detected +DEFB115 DEFB-15 ENSG00000215547 Defensin beta 115 20 31257664-31259632 Predicted secreted proteins Evidence at transcript level HPA053160 Uncertain Not detected Tissue enriched 14 epididymis: 1.3 all non-specific tissues: 0.0 Cell line enriched 16 U-2 OS: 1.6 +GAB4 ENSG00000215568 GRB2 associated binding protein family member 4 22 16961936-17008222 Predicted intracellular proteins Evidence at transcript level HPA044621 Uncertain Not detected Tissue enriched 38 testis: 3.7 all non-specific tissues: 0.0 Not detected +C20orf202 ENSG00000215595 Chromosome 20 open reading frame 202 20 1203454-1208274 Predicted intracellular proteins Evidence at transcript level HPA042786 Uncertain Mixed Tissue enhanced placenta: 4.9 lung: 1.9 Not detected +HMX1 H6, NKX5-3 ENSG00000215612 H6 family homeobox 1 4 8846076-8871817 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at transcript level Tissue enhanced Tissue enhanced cerebral cortex: 1.1 testis: 0.9 Cell line enhanced AN3-CA: 9.5;EFO-21: 5.6;HEK 293: 10.2;SH-SY5Y: 4.4 +GCGR GGR ENSG00000215644 Glucagon receptor 17 81804132-81814013 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA071228 Approved Golgi apparatus Tissue enhanced Group enriched 7 adrenal gland: 6.6;kidney: 8.4;liver: 20.8;parathyroid gland: 8.0 skin: 1.6 Cell line enhanced HeLa: 1.2;MCF7: 2.2;SK-BR-3: 1.8;U-87 MG: 2.7 +RSC1A1 RS1 ENSG00000215695 Regulator of solute carriers 1 1 15659869-15661722 Predicted intracellular proteins Evidence at protein level HPA027813, HPA028676 Approved Supported Nucleoplasm
Cell Junctions Not detected Mixed smooth muscle: 5.3 Mixed +CELA2B ELA2B, RP11-265F14.2 ENSG00000215704 Chymotrypsin like elastase family member 2B 1 15465909-15491400 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 262 pancreas: 4261.7 ovary: 16.2 Cell line enriched 5 U-138 MG: 3.8 +TMEM242 BM033, C6orf35 ENSG00000215712 Transmembrane protein 242 6 157289386-157323601 Predicted membrane proteins Evidence at protein level HPA025764 Approved Expressed in all Expressed in all cerebral cortex: 16.9 Expressed in all +TMEM167B AD-020, C1orf119, FLJ90710 ENSG00000215717 Transmembrane protein 167B 1 109089803-109096934 Predicted membrane proteins Evidence at transcript level Endometrial cancer:8.86e-4 (favourable) Expressed in all Expressed in all thyroid gland: 49.3 Expressed in all +FAM72D ENSG00000215784 Family with sequence similarity 72 member D 1 145096000-145112696 Predicted intracellular proteins Evidence at transcript level HPA043271, HPA067321 Uncertain Approved Vesicles
Plasma membrane
Cytosol Mixed Tissue enhanced lymph node: 5.6 tonsil: 4.1 Mixed +TNFRSF25 APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR ENSG00000215788 TNF receptor superfamily member 25 1 6461151-6466195 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA069834 Approved Nucleus
Plasma membrane
Actin filaments
Focal adhesion sites Renal cancer:1.65e-7 (unfavourable), Head and neck cancer:3.09e-4 (favourable), Colorectal cancer:4.46e-4 (unfavourable) Expressed in all Tissue enhanced skin: 29.6 spleen: 12.1 Cell line enhanced HDLM-2: 24.6;RPMI-8226: 17.9 +SLC35E2 KIAA0447 ENSG00000215790 Solute carrier family 35 member E2 1 1724838-1745992 Predicted membrane proteins Evidence at transcript level HPA062711 Uncertain Uncertain Nucleus Mixed Mixed thyroid gland: 7.5 Mixed +ZC3H11B ZC3HDC11B ENSG00000215817 Zinc finger CCCH-type containing 11B pseudogene 1 219608347-219613145 Predicted intracellular proteins Evidence at protein level HPA026439, HPA028490, HPA028526 Uncertain Approved Nuclear speckles Not detected Tissue enriched 13 testis: 8.1 skin: 0.6 Not detected +TSTD1 KAT ENSG00000215845 Thiosulfate sulfurtransferase like domain containing 1 1 161037631-161038990 Predicted intracellular proteins Evidence at protein level HPA006518, HPA006655 Approved Approved Cytosol
Cytoplasmic bodies Expressed in all Expressed in all thyroid gland: 146.9 Cell line enhanced SK-BR-3: 203.3;T-47d: 247.1;U-266/70: 231.6 +RPTN FLJ39117 ENSG00000215853 Repetin 1 152153595-152159228 Predicted intracellular proteins Evidence at protein level HPA030483, HPA030485 Enhanced Tissue enhanced Group enriched 34 skin: 35.1;tonsil: 47.4 esophagus: 1.2 Not detected +CYB5RL LOC606495 ENSG00000215883 Cytochrome b5 reductase like 1 54169651-54200036 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042671, HPA060463 Approved Enhanced Nucleoplasm Mixed Mixed ovary: 5.3 Expressed in all +LACTBL1 ENSG00000215906 Lactamase beta like 1 1 22953043-22965338 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.3 Not detected +C1orf167 DKFZp434E1410, RP11-56N19.2 ENSG00000215910 Chromosome 1 open reading frame 167 1 11761787-11789585 Predicted intracellular proteins Evidence at transcript level HPA039114 Uncertain Not detected Tissue enriched 30 testis: 14.7 lung: 0.4 Cell line enriched 50 U-698: 21.3 +TTC34 ENSG00000215912 Tetratricopeptide repeat domain 34 1 2635976-2801717 Predicted intracellular proteins Evidence at transcript level HPA066832 Uncertain Not detected Tissue enhanced fallopian tube: 1.6;testis: 2.6 thyroid gland: 0.8 Not detected +ATAD3C FLJ34599 ENSG00000215915 ATPase family, AAA domain containing 3C 1 1449689-1470158 Predicted intracellular proteins Evidence at protein level HPA065305 Approved Mitochondria Lung cancer:5.15e-4 (favourable) Mixed Mixed thyroid gland: 3.4 Cell line enhanced RPMI-8226: 9.0 +IFI30 GILT, IFI-30, IP-30, IP30, MGC32056 ENSG00000216490 IFI30, lysosomal thiol reductase 19 18173162-18178117 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026650 Approved Supported Vesicles
Cytosol Mixed Expressed in all appendix: 828.7 Cell line enhanced Daudi: 385.9;RPMI-8226: 408.1;U-266/84: 467.0 +IGSF23 ENSG00000216588 Immunoglobulin superfamily member 23 19 44613630-44636781 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA051811, HPA054591 Uncertain Approved Nucleus
Cell Junctions Liver cancer:7.20e-6 (favourable) Tissue enriched Group enriched 7 duodenum: 15.2;liver: 13.0;small intestine: 17.4 testis: 2.3 Cell line enhanced CACO-2: 9.0;Hep G2: 4.4;SiHa: 5.2 +GAGE12E ENSG00000216649 G antigen 12E X 49551333-49558649 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Not detected Tissue enriched 19 testis: 1.9 all non-specific tissues: 0.0 Cell line enhanced AN3-CA: 2.9;HeLa: 1.1;U-266/84: 1.4 +AC131097.4 ENSG00000216921 2 241893985-241902551 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enhanced thyroid gland: 11.5 pancreas: 6.4 Cell line enhanced REH: 2.2;SCLC-21H: 1.8 +CCDC7 BIOT2, C10orf68, FLJ13031, FLJ32762 ENSG00000216937 Coiled-coil domain containing 7 10 32446140-32882874 Predicted intracellular proteins Evidence at transcript level HPA075536 Approved Nucleoli
Mitotic spindle
Cytosol Not detected Tissue enriched 43 testis: 139.0 thyroid gland: 3.2 Mixed +FNIP1 KIAA1961 ENSG00000217128 Folliculin interacting protein 1 5 131641714-131797063 Predicted intracellular proteins Evidence at protein level HPA068099, HPA071213 Approved Expressed in all Expressed in all testis: 28.5 Expressed in all +SP9 ZNF990 ENSG00000217236 Sp9 transcription factor 2 174334946-174338492 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA062616 Uncertain Approved Mitochondria Mixed Tissue enhanced fallopian tube: 1.4 skin: 0.9 Cell line enhanced A549: 6.5;fHDF/TERT166: 4.2;THP-1: 7.8 +SYCE3 C22orf41 ENSG00000217442 Synaptonemal complex central element protein 3 22 50551112-50562905 Predicted intracellular proteins Evidence at protein level HPA047813 Approved Nucleus
Nucleoli
Golgi apparatus Mixed Tissue enriched 38 testis: 116.7 thyroid gland: 3.0 Cell line enhanced CAPAN-2: 4.5;Karpas-707: 3.1 +CKLF C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1 ENSG00000217555 Chemokine like factor 16 66552563-66566251 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA062779 Approved Vesicles Renal cancer:1.06e-9 (unfavourable), Liver cancer:5.67e-5 (unfavourable), Thyroid cancer:2.22e-4 (favourable) Expressed in all Expressed in all testis: 90.9 Expressed in all +PAM16 Magmas, Tim16, TIMM16 ENSG00000217930 Presequence translocase associated motor 16 homolog 16 4331549-4355607 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA062721 Approved Nucleoplasm
Microtubules
Mitochondria Renal cancer:5.73e-5 (unfavourable), Urothelial cancer:1.33e-4 (favourable) Expressed in all Expressed in all testis: 15.1 Expressed in all +TENM3 KIAA1455, ODZ3, Ten-M3 ENSG00000218336 Teneurin transmembrane protein 3 4 182143987-182803024 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047043 Approved Approved Nucleoplasm Mixed Tissue enhanced placenta: 18.7 parathyroid gland: 13.4 Cell line enhanced HDLM-2: 83.6;T-47d: 80.9 +CEBPZOS CEBPZ-AS1 ENSG00000218739 CEBPZ opposite strand 2 37196488-37216193 Predicted membrane proteins Evidence at protein level HPA053866 Uncertain Approved Nucleoplasm Renal cancer:3.46e-7 (unfavourable), Liver cancer:1.72e-6 (unfavourable) Expressed in all Expressed in all epididymis: 47.1 Mixed +TDRD15 ENSG00000218819 Tudor domain containing 15 2 21123917-21143272 Predicted intracellular proteins Evidence at transcript level HPA051770, HPA054675 Uncertain Not detected Tissue enriched 77 testis: 10.0 liver: 0.1 Cell line enhanced U-266/70: 5.9;U-266/84: 2.1 +PAPOLB PAPT ENSG00000218823 Poly(A) polymerase beta 7 4857733-4861994 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 539 testis: 53.9 all non-specific tissues: 0.0 Not detected +ZNF579 FLJ35453 ENSG00000218891 Zinc finger protein 579 19 55576770-55580845 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062812 Approved Approved Nucleus Renal cancer:1.00e-5 (unfavourable) Expressed in all Expressed in all gallbladder: 13.0 Expressed in all +CELA3B CBPP, ELA3B ENSG00000219073 Chymotrypsin like elastase family member 3B 1 21977021-21998642 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028086, HPA045650 Supported Approved Cytosol Tissue enriched Tissue enriched 296 pancreas: 10568.2 ovary: 35.6 Mixed +RNASEK MGC71993 ENSG00000219200 Ribonuclease K 17 7012417-7014532 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level HPA044708 Uncertain Pancreatic cancer:1.92e-4 (favourable) Expressed in all Expressed in all adrenal gland: 468.1 Expressed in all +TEX40 C11orf20, DKFZP566E164 ENSG00000219435 Testis expressed 40 11 64300391-64304770 Predicted intracellular proteins Evidence at protein level HPA052822 Approved Nucleoplasm Not detected Tissue enriched 105 testis: 519.6 cerebral cortex: 4.9 Cell line enhanced CACO-2: 11.9;PC-3: 7.8;T-47d: 6.5 +FAM19A5 TAFA-5 ENSG00000219438 Family with sequence similarity 19 member A5, C-C motif chemokine like 22 48489460-48850912 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level CAB025629 Approved Expressed in all Tissue enhanced cerebral cortex: 49.9 cervix, uterine: 12.9 Cell line enhanced fHDF/TERT166: 15.8;HEK 293: 12.4;Hep G2: 21.7;NTERA-2: 17.3;SCLC-21H: 10.2;U-2 OS: 24.8 +NBPF1 FLJ20719, KIAA1693 ENSG00000219481 Neuroblastoma breakpoint family member 1 1 16562319-16613562 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Renal cancer:1.06e-4 (favourable) Expressed in all Mixed testis: 21.9 Mixed +UMAD1 RPA3-AS1, RPA3OS ENSG00000219545 UBAP1-MVB12-associated (UMA) domain containing 1 7 7640711-7968020 Predicted intracellular proteins Evidence at protein level HPA044806 Approved Approved Nucleoplasm Renal cancer:1.73e-8 (favourable) Expressed in all Expressed in all thyroid gland: 41.1 Expressed in all +PPP1R3G ENSG00000219607 Protein phosphatase 1 regulatory subunit 3G 6 5084581-5089487 Predicted intracellular proteins Evidence at protein level HPA056393 Uncertain Tissue enhanced Mixed spleen: 3.6 Cell line enhanced EFO-21: 3.4;PC-3: 3.3;THP-1: 8.6 +FAM228B ENSG00000219626 Family with sequence similarity 228 member B 2 24076526-24169640 Predicted intracellular proteins Evidence at protein level HPA052598, HPA063357 Uncertain Approved Golgi apparatus Mixed Mixed testis: 36.5 Mixed +LINGO3 LERN2, LRRN6B ENSG00000220008 Leucine rich repeat and Ig domain containing 3 19 2289784-2292024 Predicted membrane proteins Evidence at protein level HPA043781, HPA055932, HPA059558 Uncertain Approved Mitochondria Tissue enhanced Tissue enhanced appendix: 1.6;cerebral cortex: 1.6;spleen: 3.7 lymph node: 1.2 Group enriched 6 HMC-1: 15.2;RPMI-8226: 3.0 +ZGLP1 GATAD3, GLP-1, GLP1 ENSG00000220201 Zinc finger, GATA-like protein 1 19 10304803-10309880 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049855 Uncertain Approved Nucleus
Vesicles Mixed Mixed testis: 3.1 Cell line enhanced NB-4: 20.8 +VAMP2 SYB2, VAMP-2 ENSG00000220205 Vesicle associated membrane protein 2 17 8159149-8163546 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB078785 Supported Renal cancer:9.76e-8 (favourable), Pancreatic cancer:3.83e-6 (favourable), Endometrial cancer:1.08e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 483.5 Expressed in all +OR6B1 OR7-3 ENSG00000221813 Olfactory receptor family 6 subfamily B member 1 7 144003929-144004983 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA053164 Uncertain Not detected Not detected testis: 0.3 Not detected +EBF2 COE2, FLJ11500 ENSG00000221818 Early B-cell factor 2 8 25841730-26045397 Predicted intracellular proteins, Transcription factors Evidence at protein level Renal cancer:2.51e-6 (unfavourable) Mixed Tissue enhanced adipose tissue: 20.8 heart muscle: 6.6 Group enriched 16 ASC diff: 15.6;ASC TERT1: 32.1;HSkMC: 34.2;hTEC/SVTERT24-B: 26.8;U-138 MG: 17.0;U-2197: 21.1;U-87 MG: 18.8 +C6orf226 LOC441150 ENSG00000221821 Chromosome 6 open reading frame 226 6 42890265-42890816 Predicted intracellular proteins Evidence at protein level HPA045350 Approved Approved Nuclear speckles Breast cancer:1.93e-5 (favourable), Renal cancer:3.35e-4 (favourable), Pancreatic cancer:5.13e-4 (favourable) Expressed in all Expressed in all adrenal gland: 13.4 Mixed +PPP3R1 CALNB1, CNB, CNB1 ENSG00000221823 Protein phosphatase 3 regulatory subunit B, alpha 2 68178857-68256237 Predicted intracellular proteins Evidence at protein level CAB005610, HPA047157 Approved Approved Plasma membrane
Cytosol Endometrial cancer:9.08e-6 (unfavourable), Renal cancer:1.70e-5 (unfavourable), Liver cancer:5.37e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 197.5 Expressed in all +PSG3 ENSG00000221826 Pregnancy specific beta-1-glycoprotein 3 19 42721638-42740569 Predicted secreted proteins Evidence at protein level HPA046327 Approved Not detected Tissue enriched 162 placenta: 188.8 testis: 1.1 Cell line enriched 6 U-2197: 1.2 +FANCG FAG, XRCC9 ENSG00000221829 Fanconi anemia complementation group G 9 35073835-35080016 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB008105, HPA045335 Approved Supported Nucleoli
Plasma membrane
Cytosol Renal cancer:2.38e-7 (unfavourable), Liver cancer:2.02e-4 (unfavourable) Expressed in all Mixed fallopian tube: 8.7 Expressed in all +OR2A5 OR2A26, OR2A8, OR7-138, OR7-141 ENSG00000221836 Olfactory receptor family 2 subfamily A member 5 7 144050368-144051380 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP10-9 KAP10.9, KAP18.9, KRTAP18-9 ENSG00000221837 Keratin associated protein 10-9 21 44627123-44628293 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +AP4M1 MU-4, MU-ARP2, SPG50 ENSG00000221838 Adaptor related protein complex 4 mu 1 subunit 7 100101549-100110345 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA066774 Approved Liver cancer:7.63e-5 (unfavourable), Renal cancer:8.29e-4 (unfavourable) Expressed in all Expressed in all testis: 28.8 Expressed in all +OR4A5 ENSG00000221840 Olfactory receptor family 4 subfamily A member 5 11 54706885-54707832 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +C2orf16 DKFZp434G118 ENSG00000221843 Chromosome 2 open reading frame 16 2 27537386-27582721 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052136, HPA056962 Uncertain Uncertain Nuclear bodies Mixed Tissue enriched 19 testis: 14.6 cerebral cortex,thyroid gland: 0.7 Cell line enhanced SCLC-21H: 2.9;SiHa: 1.9 +KRTAP1-5 KAP1.5 ENSG00000221852 Keratin associated protein 1-5 17 41026026-41027202 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 14 cervix, uterine: 2.1 urinary bladder: 0.1 Cell line enhanced BJ: 23.6;BJ hTERT+: 9.7;fHDF/TERT166: 28.2;LHCN-M2: 14.9 +TAS2R41 T2R59 ENSG00000221855 Taste 2 receptor member 41 7 143477873-143478796 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA057063 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR2A12 OR2A12P ENSG00000221858 Olfactory receptor family 2 subfamily A member 12 7 144095048-144096093 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP10-10 KAP10.10, KAP18.10, KRTAP18-10 ENSG00000221859 Keratin associated protein 10-10 21 44637356-44638455 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP12-2 KAP12.2, KRTAP12.2 ENSG00000221864 Keratin associated protein 12-2 21 44666189-44666927 Predicted intracellular proteins Evidence at protein level Not detected Not detected epididymis: 0.1 Not detected +PLXNA4 DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B ENSG00000221866 Plexin A4 7 132123332-132648688 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA029919, HPA052141, HPA075592 Approved Approved Plasma membrane Endometrial cancer:1.61e-6 (unfavourable) Tissue enhanced Tissue enhanced adipose tissue: 15.2;cervix, uterine: 12.5 cerebral cortex: 10.4 Cell line enhanced ASC diff: 17.3;HMC-1: 15.0;RH-30: 17.9;TIME: 46.9 +MAGEA3 CT1.3, HIP8, HYPD, MAGE3, MGC14613 ENSG00000221867 MAGE family member A3 X 152698752-152702347 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Liver cancer:3.58e-4 (unfavourable) Mixed Tissue enriched 28 testis: 12.8 placenta: 0.4 Cell line enhanced K-562: 157.8;PC-3: 145.8;SH-SY5Y: 163.2;SK-BR-3: 132.6;U-266/70: 187.5;U-266/84: 205.2 +CEBPD C/EBP-delta, CELF, CRP3, NF-IL6-beta ENSG00000221869 CCAAT/enhancer binding protein delta 8 47736909-47739086 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067581 Supported Nucleoplasm Renal cancer:2.87e-7 (unfavourable), Breast cancer:2.28e-5 (favourable) Expressed in all Expressed in all adipose tissue: 71.1 Cell line enhanced HHSteC: 29.5;NB-4: 50.0;SiHa: 33.7 +TMEM257 CXorf1 ENSG00000221870 Transmembrane protein 257 X 145827410-145829850 Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enriched 10 cerebral cortex: 4.2 seminal vesicle: 0.4 Not detected +ZNF816-ZNF321P ZNF816-ZNF321 ENSG00000221874 ZNF816-ZNF321P readthrough 19 52928475-52962823 Predicted intracellular proteins Evidence at transcript level HPA051271 Uncertain Uncertain Nucleoplasm Not detected Tissue enhanced prostate: 2.7 rectum: 1.6 Cell line enriched 7 RT4: 7.2 +PSG7 ENSG00000221878 Pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 19 42924132-42937178 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046327 Approved Not detected Tissue enhanced placenta: 5.8;skin: 1.4 smooth muscle: 0.9 Cell line enhanced BJ: 1.3;HBF TERT88: 2.2;U-2197: 1.7 +KRTAP1-3 KAP1.3 ENSG00000221880 Keratin associated protein 1-3 17 41033884-41034855 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +OR3A2 OLFRA04, OR17-228, OR228 ENSG00000221882 Olfactory receptor family 3 subfamily A member 2 17 3277899-3278974 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enriched 6 testis: 5.3 epididymis: 0.9 Cell line enriched 6 HDLM-2: 10.0 +ARIH2OS C3orf71 ENSG00000221883 Ariadne homolog 2 opposite strand 3 48917788-48919385 Predicted membrane proteins Evidence at transcript level Mixed Mixed testis: 4.2 Mixed +ZBED8 Buster3, C5orf54 ENSG00000221886 Zinc finger BED-type containing 8 5 160393148-160400097 Predicted intracellular proteins Evidence at protein level HPA045445, HPA055817 Approved Enhanced Nucleoplasm Pancreatic cancer:3.72e-4 (favourable) Expressed in all Mixed ovary: 13.3 Mixed +HMSD ACC-6, ACC6, C18orf53 ENSG00000221887 Histocompatibility minor serpin domain containing 18 63949301-63981774 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enhanced Mixed cerebral cortex,lymph node: 1.8 Cell line enhanced ASC TERT1: 5.1;HDLM-2: 17.2;Karpas-707: 5.0 +OR1C1 HSTPCR27, TPCR27 ENSG00000221888 Olfactory receptor family 1 subfamily C member 1 1 247757462-247758406 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 22 testis: 2.2 all non-specific tissues: 0.0 Not detected +NPTXR ENSG00000221890 Neuronal pentraxin receptor 22 38818452-38843982 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001079 Enhanced Approved Nucleoplasm
Plasma membrane
Cytosol Endometrial cancer:2.85e-4 (unfavourable), Cervical cancer:3.93e-4 (favourable) Expressed in all Tissue enriched 13 cerebral cortex: 176.4 prostate: 13.3 Cell line enhanced SCLC-21H: 36.6;U-87 MG: 86.8 +POM121L12 DKFZp564N2472 ENSG00000221900 POM121 transmembrane nucleoporin like 12 7 53035642-53036924 Predicted intracellular proteins Evidence at protein level HPA027836 Enhanced Not detected Tissue enriched 88 testis: 8.7 all non-specific tissues: 0.0 Not detected +FAM200A C7orf38, DKFZp727G131, FLJ36794 ENSG00000221909 Family with sequence similarity 200 member A 7 99546308-99558536 Predicted intracellular proteins Evidence at protein level HPA017855 Uncertain Renal cancer:2.17e-7 (favourable), Liver cancer:9.24e-4 (unfavourable) Expressed in all Mixed testis: 15.1 Expressed in all +OR2F2 OR7-1 ENSG00000221910 Olfactory receptor family 2 subfamily F member 2 7 143935166-143936279 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +PPP2R2A B55A, PR52A, PR55A ENSG00000221914 Protein phosphatase 2 regulatory subunit Balpha 8 26291491-26372680 Predicted intracellular proteins Evidence at protein level HPA042122, HPA042770, CAB079289 Approved Approved Cytosol Expressed in all Expressed in all placenta: 72.2 Expressed in all +C19orf73 FLJ10490 ENSG00000221916 Chromosome 19 open reading frame 73 19 49118397-49119140 Predicted intracellular proteins Evidence at protein level HPA062719 Uncertain Approved Nucleus
Cytosol Pancreatic cancer:1.58e-4 (favourable) Expressed in all Mixed duodenum: 2.2 Cell line enhanced HEK 293: 7.8 +ZNF880 ENSG00000221923 Zinc finger protein 880 19 52369917-52385795 Predicted intracellular proteins, Transcription factors Evidence at transcript level Renal cancer:4.33e-8 (favourable) Expressed in all Expressed in all thyroid gland: 31.2 Mixed +TRIM16 EBBP ENSG00000221926 Tripartite motif containing 16 17 15627960-15684311 Predicted intracellular proteins Evidence at protein level HPA023623, HPA066431 Uncertain Supported Plasma membrane
Cytosol Liver cancer:3.94e-4 (unfavourable), Urothelial cancer:6.71e-4 (unfavourable) Expressed in all Expressed in all esophagus: 117.8 Cell line enhanced A549: 255.9;HaCaT: 197.9 +OR6X1 ENSG00000221931 Olfactory receptor family 6 subfamily X member 1 11 123753488-123754545 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected epididymis: 0.1 Not detected +HEPN1 ENSG00000221932 Hepatocellular carcinoma, down-regulated 1 11 124919244-124920677 Predicted intracellular proteins Evidence at transcript level HPA043768, HPA063054 Uncertain Approved Golgi apparatus Not detected Tissue enriched 7 cerebral cortex: 79.5 adipose tissue: 11.1 Cell line enriched 358 Hep G2: 35.7 +OR2A25 OR2A25P, OR2A27 ENSG00000221933 Olfactory receptor family 2 subfamily A member 25 7 144074182-144075195 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA058272 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +TAS2R40 GPR60 ENSG00000221937 Taste 2 receptor member 40 7 143222037-143223079 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected appendix: 0.9 Not detected +OR2A14 OR2A14P, OR2A6, OST182 ENSG00000221938 Olfactory receptor family 2 subfamily A member 14 7 144129058-144130069 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +TIGD1 EEYORE ENSG00000221944 Tigger transposable element derived 1 2 232547968-232550592 Predicted intracellular proteins Evidence at protein level HPA041717 Approved Supported Nucleus
Nucleoli
Nuclear bodies Renal cancer:4.41e-5 (unfavourable) Expressed in all Expressed in all testis: 16.3 Expressed in all +FXYD7 ENSG00000221946 FXYD domain containing ion transport regulator 7 19 35143250-35154301 Predicted membrane proteins Evidence at protein level HPA026916 Approved Tissue enhanced Tissue enriched 35 cerebral cortex: 105.8 lymph node: 3.0 Cell line enhanced HAP1: 1.8;HMC-1: 4.5;WM-115: 3.1 +XKR9 ENSG00000221947 XK related 9 8 70669365-70790371 Predicted membrane proteins, Transporters Evidence at transcript level HPA044430 Uncertain Approved Mitochondria Pancreatic cancer:7.20e-4 (unfavourable) Mixed Tissue enhanced testis: 13.8 small intestine: 6.1 Cell line enhanced hTCEpi: 4.6 +OR4C12 ENSG00000221954 Olfactory receptor family 4 subfamily C member 12 11 49981473-49982535 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +SLC12A8 CCC9 ENSG00000221955 Solute carrier family 12 member 8 3 125082636-125212864 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA031123 Uncertain Supported Nucleoplasm Renal cancer:5.56e-4 (unfavourable) Expressed in all Tissue enhanced thyroid gland: 39.6 gallbladder: 16.2 Cell line enhanced HHSteC: 28.8;U-2197: 63.6 +PRR21 ENSG00000221961 Proline rich 21 2 240041813-240042982 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +APOL6 APOL-VI, APOLVI ENSG00000221963 Apolipoprotein L6 22 35648395-35668409 Predicted membrane proteins Evidence at protein level CAB028574, HPA029165, HPA029167 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Urothelial cancer:6.61e-4 (favourable) Expressed in all Mixed adipose tissue: 25.4 Mixed +FADS3 CYB5RP, LLCDL3 ENSG00000221968 Fatty acid desaturase 3 11 61873519-61892051 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045224 Approved Approved Nucleoli fibrillar center Renal cancer:1.50e-9 (unfavourable), Head and neck cancer:9.54e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 99.2 Expressed in all +OR2A1 ENSG00000221970 Olfactory receptor family 2 subfamily A member 1 7 144318125-144319057 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA058272 Uncertain Not detected Tissue enhanced thyroid gland: 2.8 ovary: 1.1 Not detected +C3orf36 FLJ22173 ENSG00000221972 Chromosome 3 open reading frame 36 3 133928145-133929812 Predicted intracellular proteins Evidence at transcript level HPA046432 Uncertain Mixed Tissue enriched 7 seminal vesicle: 11.8 parathyroid gland: 1.6 Cell line enhanced EFO-21: 2.2;TIME: 1.5 +OR4E2 ENSG00000221977 Olfactory receptor family 4 subfamily E member 2 14 21665083-21666024 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.1 Not detected +CCNL2 ania-6b, CCNM, CCNS, HLA-ISO, PCEE, SB138 ENSG00000221978 Cyclin L2 1 1385711-1399328 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053137 Supported Supported Nucleoplasm Urothelial cancer:1.46e-7 (favourable), Renal cancer:1.12e-6 (unfavourable) Expressed in all Expressed in all endometrium: 68.7 Expressed in all +UBA52 CEP52, HUBCEP52, L40, MGC126879, MGC126881, MGC57125, RPL40 ENSG00000221983 Ubiquitin A-52 residue ribosomal protein fusion product 1 19 18571730-18577550 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA041344, HPA049132, HPA056624 Supported Approved Nucleoplasm
Endoplasmic reticulum
Plasma membrane
Cytosol Expressed in all Expressed in all ovary: 1914.0 Expressed in all +MYBPHL ENSG00000221986 Myosin binding protein H like 1 109292365-109307041 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 14 heart muscle: 53.2 fallopian tube: 3.7 Cell line enhanced Hep G2: 1.7;RH-30: 1.3 +PPT2 ENSG00000221988 Palmitoyl-protein thioesterase 2 6 32153441-32163680 Predicted secreted proteins Evidence at protein level Endometrial cancer:5.03e-5 (unfavourable) Expressed in all Mixed skin: 8.6 Cell line enhanced ASC diff: 16.4;EFO-21: 16.9;HEK 293: 29.1;SK-MEL-30: 16.2 +OR2A2 OR2A17P, OR2A2P, OST008 ENSG00000221989 Olfactory receptor family 2 subfamily A member 2 7 144109514-144110564 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF630 BC037316, dJ54B20.2, FLJ20573, MGC138344 ENSG00000221994 Zinc finger protein 630 X 47983356-48071658 Predicted intracellular proteins Evidence at protein level HPA001053, HPA068130 Supported Approved Nucleus
Cytosol Mixed Mixed parathyroid gland: 7.5 Cell line enhanced SiHa: 5.2 +TIAF1 ENSG00000221995 TGFB1-induced anti-apoptotic factor 1 17 29073521-29078857 Predicted intracellular proteins Evidence at transcript level HPA051129 Uncertain Mixed Mixed skin: 4.8 Cell line enhanced REH: 6.4 +BTBD19 ENSG00000222009 BTB domain containing 19 1 44808482-44815585 Predicted intracellular proteins Evidence at protein level HPA042633 Uncertain Renal cancer:4.18e-8 (unfavourable) Mixed Mixed endometrium: 4.5 Cell line enhanced TIME: 9.7 +FAM185A MGC35361 ENSG00000222011 Family with sequence similarity 185 member A 7 102748971-102809225 Predicted intracellular proteins Evidence at protein level HPA020470, HPA029883 Uncertain Enhanced Cytosol Renal cancer:9.36e-5 (favourable) Expressed in all Mixed parathyroid gland: 4.5 Mixed +RAB6C WTH3 ENSG00000222014 RAB6C, member RAS oncogene family 2 129979664-129982738 Predicted intracellular proteins Evidence at protein level HPA059131 Uncertain Uncertain Golgi apparatus Tissue enhanced Tissue enhanced parathyroid gland: 7.5 breast: 3.2 Group enriched 6 BEWO: 2.4;HMC-1: 1.9;REH: 4.9;T-47d: 3.0;U-266/70: 1.6 +C21orf140 ENSG00000222018 Chromosome 21 open reading frame 140 21 34400317-34401072 Predicted intracellular proteins Evidence at transcript level HPA045123 Uncertain Not detected Tissue enhanced cerebral cortex: 2.6;testis: 4.0 esophagus: 1.1 Not detected +PSMB11 beta5t ENSG00000222028 Proteasome subunit beta 11 14 23042167-23044276 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028967, HPA056970 Enhanced Not detected Not detected testis: 0.2 Not detected +POTEM ACT, P704P, POTE14beta ENSG00000222036 POTE ankyrin domain family member M 14 18967434-18999012 Predicted intracellular proteins No evidence HPA042822 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +POTEJ POTE2beta ENSG00000222038 POTE ankyrin domain family member J 2 130611481-130658091 Predicted intracellular proteins Evidence at protein level HPA041264, HPA041271, HPA042822, HPA043260 Uncertain Not detected Tissue enhanced testis: 1.1 prostate: 0.6 Not detected +DCDC2B ENSG00000222046 Doublecortin domain containing 2B 1 32209094-32216196 Predicted intracellular proteins Evidence at protein level HPA045832 Uncertain Mixed Tissue enriched 17 fallopian tube: 44.3 lung: 2.6 Not detected +C10orf55 bA417O11.3 ENSG00000222047 Chromosome 10 open reading frame 55 10 73909969-73922777 Predicted intracellular proteins Evidence at protein level HPA045739 Uncertain Approved Nucleus Mixed Not detected epididymis,kidney: 0.4 Cell line enhanced A-431: 2.4;CAPAN-2: 2.3;HaCaT: 2.3;RPTEC TERT1: 3.0 +RP11-211G3.2 ENSG00000223401 3 187743686-187746028 Predicted intracellular proteins Evidence at transcript level Breast cancer:6.93e-4 (favourable) Mixed Tissue enhanced skeletal muscle: 8.0 bone marrow: 4.5 Cell line enhanced Daudi: 2.1;U-698: 4.6 +TRIM49D1 TRIM49D, TRIM49D1P, TRIM49DP ENSG00000223417 Tripartite motif containing 49D1 11 89911111-89921767 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.1 Not detected +USP17L2 DUB3 ENSG00000223443 Ubiquitin specific peptidase 17-like family member 2 8 12137168-12139077 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +EXOSC6 EAP4, hMtr3p, MTR3, Mtr3p, p11 ENSG00000223496 Exosome component 6 16 70246778-70251930 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all cerebral cortex: 22.9 Expressed in all +VPS52 ARE1, SACM2L ENSG00000223501 VPS52, GARP complex subunit 6 33250272-33272047 Predicted intracellular proteins Evidence at protein level HPA042667, HPA048128 Approved Expressed in all Mixed thyroid gland: 8.6 Mixed +CDRT15 ENSG00000223510 CMT1A duplicated region transcript 15 17 14235673-14236862 Predicted intracellular proteins Evidence at protein level HPA055952 Uncertain Not detected Tissue enhanced testis: 11.5 skin: 4.0 Mixed +ZNF844 FLJ14959 ENSG00000223547 Zinc finger protein 844 19 12064699-12081565 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046982 Uncertain Renal cancer:0.00e+0 (favourable) Expressed in all Mixed thyroid gland: 20.3 Cell line enhanced U-266/84: 12.3 +USP17L15 ENSG00000223569 Ubiquitin specific peptidase 17-like family member 15 4 9234385-9236334 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +CKMT1A CKMT1 ENSG00000223572 Creatine kinase, mitochondrial 1A 15 43692886-43699222 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level HPA043491 Uncertain Mixed Mixed rectum: 73.8 Cell line enhanced HaCaT: 113.0;SCLC-21H: 52.4;SK-BR-3: 74.4;T-47d: 83.6 +TINCR FLJ90734, LINC00036, NCRNA00036, onco-lncRNA-16, PLAC2 ENSG00000223573 Tissue differentiation-inducing non-protein coding RNA 19 5558167-5568034 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 6 skin: 107.2 placenta: 19.0 Cell line enhanced BEWO: 31.4;HaCaT: 25.8;SK-BR-3: 31.6 +CENPVL1 CENPVP1, PRR6L1 ENSG00000223591 Centromere protein V like 1 X 51710512-51712131 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced testis: 3.0 cerebral cortex: 0.8 Cell line enhanced NTERA-2: 2.1;PC-3: 4.2;U-2 OS: 3.6 +EBLN1 ENSG00000223601 Endogenous Bornavirus-like nucleoprotein 1 10 22208814-22210021 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 43 testis: 4.2 all non-specific tissues: 0.0 Not detected +HBD ENSG00000223609 Hemoglobin subunit delta 11 5232678-5235370 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB037087, HPA043234 Supported Approved Vesicles Not detected Tissue enriched 64 bone marrow: 1221.3 placenta: 19.0 Cell line enhanced HEL: 13.7;HMC-1: 14.7;U-266/70: 73.6;U-266/84: 12.8 +ZNF735 ZNF735P ENSG00000223614 Zinc finger protein 735 7 64207090-64220508 Predicted intracellular proteins, Transcription factors Evidence at protein level Not detected Not detected testis: 0.1 Not detected +RFPL4A RFPL4, RNF210 ENSG00000223638 Ret finger protein like 4A 19 55759014-55763175 Predicted intracellular proteins Evidence at protein level HPA046368 Uncertain Approved Centrosome
Cytosol Tissue enriched Tissue enhanced epididymis: 2.5;testis: 2.5 liver: 1.2 Cell line enriched 19 U-2 OS: 88.7 +C1GALT1C1L ENSG00000223658 C1GALT1-specific chaperone 1 like 2 43675151-43676322 Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced testis: 11.8 epididymis: 8.2 Cell line enhanced SH-SY5Y: 15.3;U-2 OS: 9.4 +CERS1 LAG1, LASS1, UOG1 ENSG00000223802 Ceramide synthase 1 19 18868545-18896727 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA045724 Approved Approved Endoplasmic reticulum Tissue enhanced Group enriched 13 cerebral cortex: 136.3;testis: 28.0 skeletal muscle: 6.5 Cell line enhanced AN3-CA: 28.0;HEK 293: 28.4 +HLA-DPB1 HLA-DP1B ENSG00000223865 Major histocompatibility complex, class II, DP beta 1 6 33075926-33087201 Predicted membrane proteins Evidence at protein level HPA011078, HPA058509 Approved Approved Nucleus
Cell Junctions Endometrial cancer:3.38e-4 (favourable) Expressed in all Expressed in all spleen: 170.6 Group enriched 7 HDLM-2: 102.6;REH: 48.0 +C1QTNF5 CTRP5, DKFZp586B0621, LORD ENSG00000223953 C1q and tumor necrosis factor related protein 5 11 119338939-119340940 Disease related genes, Predicted secreted proteins Evidence at protein level CAB025607, HPA038604 Uncertain Not detected Mixed gallbladder: 71.5 Cell line enhanced HHSteC: 30.0;HUVEC TERT2: 45.5;TIME: 41.0 +CPTP GLTPD1, MGC10334 ENSG00000224051 Ceramide-1-phosphate transfer protein 1 1324756-1328897 Predicted intracellular proteins Evidence at protein level HPA056832 Approved Approved Cytosol Renal cancer:1.75e-4 (favourable) Expressed in all Expressed in all testis: 47.0 Expressed in all +CT47A10 CT47.10 ENSG00000224089 Cancer/testis antigen family 47, member A10 X 120938701-120942023 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 20 testis: 2.0 all non-specific tissues: 0.0 Not detected +LINC00633 ENSG00000224107 Long intergenic non-protein coding RNA 633 X 135118955-135120526 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 63 testis: 15.1 bone marrow: 0.2 Not detected +CENPVL3 CENPVP3 ENSG00000224109 Centromere protein V like 3 X 51618055-51618918 Predicted intracellular proteins Evidence at transcript level Not detected Not detected cerebral cortex: 0.7 Cell line enhanced NTERA-2: 2.2;PC-3: 12.7;U-2 OS: 6.4 +PRR29 C17orf72, DKFZp761M2312, FLJ11724 ENSG00000224383 Proline rich 29 17 63998351-64004304 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 12 fallopian tube: 92.9 testis: 7.9 Cell line enhanced CAPAN-2: 3.0;REH: 3.3;TIME: 2.3 +C4B C4B1, C4B3, C4F, CH, CO4, CPAMD3 ENSG00000224389 Complement C4B (Chido blood group) 6 32014762-32035418 Blood group antigen proteins, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA046356, HPA048287, HPA050103 Approved Tissue enhanced Tissue enhanced adrenal gland: 59.4;liver: 65.5 fallopian tube,kidney: 18.3 Cell line enriched 5 Karpas-707: 92.1 +ADM5 AM5, C19orf76 ENSG00000224420 Adrenomedullin 5 (putative) 19 49688664-49690575 Predicted secreted proteins Evidence at transcript level Urothelial cancer:6.74e-4 (favourable) Mixed Mixed skin: 2.6 Mixed +CXorf51A CXorf51 ENSG00000224440 Chromosome X open reading frame 51A X 146814106-146814726 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ATXN1L BOAT1 ENSG00000224470 Ataxin 1 like 16 71845991-71885268 Predicted intracellular proteins Evidence at protein level HPA062596, HPA062789 Enhanced Nucleus Renal cancer:5.33e-8 (favourable), Urothelial cancer:8.42e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.6 Expressed in all +SMIM13 C6orf228 ENSG00000224531 Small integral membrane protein 13 6 11094033-11138733 Predicted membrane proteins Evidence at protein level HPA065706 Enhanced Approved Nucleus
Nuclear membrane
Golgi apparatus Renal cancer:1.03e-5 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 47.1 placenta: 18.9 Expressed in all +GPX5 ENSG00000224586 Glutathione peroxidase 5 6 28525925-28534952 Enzymes, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 30 epididymis: 12.2 seminal vesicle: 0.4 Not detected +GAGE12J GAGE11 ENSG00000224659 G antigen 12J X 49322057-49329384 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Not detected Tissue enriched 34 testis: 32.7 epididymis: 0.9 Group enriched 6 AN3-CA: 132.7;K-562: 134.5 +NPIPA3 ENSG00000224712 Nuclear pore complex interacting protein family member A3 16 14708944-14726338 Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Mixed Mixed parathyroid gland: 4.3 Cell line enhanced NB-4: 6.7;SK-MEL-30: 11.7 +NDUFAF8 C17orf89 ENSG00000224877 NADH:ubiquinone oxidoreductase complex assembly factor 8 17 81239239-81241281 Predicted intracellular proteins Evidence at protein level HPA057732 Uncertain Approved Mitochondria Renal cancer:1.70e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 63.7 Expressed in all +GAGE12H ENSG00000224902 G antigen 12H X 49579983-49587301 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Approved Golgi apparatus
Plasma membrane
Cytosol Not detected Tissue enriched 392 testis: 39.2 all non-specific tissues: 0.0 Group enriched 44 A-431: 47.0;U-266/84: 113.6 +APOC4-APOC2 ENSG00000224916 APOC4-APOC2 readthrough (NMD candidate) 19 44942238-44949565 Predicted membrane proteins Evidence at protein level HPA055877 Supported Tissue enriched Tissue enriched 102 liver: 109.7 cerebral cortex: 1.0 Cell line enhanced HMC-1: 1.0;THP-1: 4.2 +PRRT4 ENSG00000224940 Proline rich transmembrane protein 4 7 128350325-128361685 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA046373, HPA052681 Uncertain Approved Nucleoplasm
Peroxisomes
Plasma membrane Mixed Group enriched 12 adipose tissue: 15.7;bone marrow: 41.2 cerebral cortex: 2.2 Cell line enriched 8 SH-SY5Y: 239.1 +PPP4R3CP FLFL3P, FLJ32867, SMEK3P, smk1 ENSG00000224960 Protein phosphatase 4 regulatory subunit 3C, pseudogene X 27460211-27463341 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enriched 11 testis: 3.6 placenta: 0.3 Cell line enriched 146 U-2197: 19.0 +TMEM233 IFITMD2 ENSG00000224982 Transmembrane protein 233 12 119593459-119643066 Predicted membrane proteins Evidence at transcript level HPA047506 Uncertain Tissue enriched Group enriched 5 cerebral cortex: 16.2;skeletal muscle: 11.5;thyroid gland: 21.4 parathyroid gland: 3.1 Cell line enhanced hTEC/SVTERT24-B: 19.8;RH-30: 10.2;U-2197: 14.8;U-87 MG: 61.5 +LL0XNC01-16G2.1 ENSG00000225110 X 153317681-153321822 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 4.0 adrenal gland: 0.9 Not detected +AATK-AS1 ENSG00000225180 AATK antisense RNA 1 17 81165507-81183164 Predicted intracellular proteins No evidence Not detected Not detected adipose tissue,cerebral cortex: 0.1 Not detected +PLEKHM1 KIAA0356 ENSG00000225190 Pleckstrin homology and RUN domain containing M1 17 45435900-45490749 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA025018, HPA039473 Approved Supported Nucleoli
Vesicles Endometrial cancer:1.28e-6 (favourable), Liver cancer:3.25e-4 (unfavourable) Expressed in all Mixed esophagus: 11.8 Mixed +USP17L3 USP17B, USP17F ENSG00000225327 Ubiquitin specific peptidase 17-like family member 3 8 7976393-7977985 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +CT62 ENSG00000225362 Cancer/testis antigen 62 15 71110244-71115494 Predicted intracellular proteins Evidence at transcript level HPA045306 Uncertain Group enriched Tissue enriched 86 testis: 50.1 prostate: 0.5 Cell line enhanced HaCaT: 1.4;T-47d: 3.2;U-2197: 2.5 +FAM236D ENSG00000225396 Family with sequence similarity 236 member D X 72807425-72808210 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 23 testis: 3.5 prostate: 0.1 Not detected +MKRN2OS C3orf83, MKRN2-AS1 ENSG00000225526 MKRN2 opposite strand 3 12514934-12561059 Predicted intracellular proteins Evidence at transcript level HPA065586, HPA065753 Uncertain Approved Golgi apparatus Mixed Tissue enhanced epididymis: 11.1 small intestine: 8.4 Cell line enhanced CAPAN-2: 12.4;RT4: 4.7;T-47d: 3.1 +RP3-370M22.8 ENSG00000225528 22 39960397-39964718 Predicted intracellular proteins Evidence at transcript level HPA047397 Uncertain Nucleus
Nucleoli
Nuclear bodies Not detected Not detected bone marrow,lymph node: 0.8 Cell line enhanced HEL: 2.7;K-562: 11.1;MOLT-4: 1.7 +C2CD4D FAM148D ENSG00000225556 C2 calcium dependent domain containing 4D 1 151837819-151840557 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced skin: 1.9 cerebral cortex: 1.2 Cell line enriched 8 HDLM-2: 17.9 +ZNF469 KIAA1858 ENSG00000225614 Zinc finger protein 469 16 88427471-88440757 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA069784 Approved Vesicles Mixed Mixed cervix, uterine: 2.2 Cell line enhanced SiHa: 5.3;THP-1: 4.3 +MCRIP1 FAM195B, GRAN2, MCRIP ENSG00000225663 MAPK regulated corepressor interacting protein 1 17 81822361-81833302 Predicted intracellular proteins Evidence at protein level HPA045542 Approved Approved Cytosol Pancreatic cancer:2.26e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 107.1 Expressed in all +SLC26A6 DKFZp586E1422 ENSG00000225697 Solute carrier family 26 member 6 3 48625723-48635493 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA048363 Approved Uncertain Cytosol Renal cancer:1.53e-5 (unfavourable), Liver cancer:3.92e-4 (unfavourable) Expressed in all Expressed in all rectum: 24.0 Expressed in all +OR6V1 GPR138 ENSG00000225781 Olfactory receptor family 6 subfamily V member 1 7 143052320-143053347 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +CTD-2313N18.7 ENSG00000225805 11 71878453-71884561 Predicted secreted proteins Evidence at transcript level Mixed Tissue enriched 13 epididymis: 86.1 thyroid gland: 6.4 Cell line enhanced RH-30: 16.4 +FAM229A ENSG00000225828 Family with sequence similarity 229 member A 1 32361270-32364278 Predicted intracellular proteins Evidence at transcript level Renal cancer:1.73e-5 (unfavourable), Urothelial cancer:2.33e-4 (favourable) Mixed Tissue enriched 7 testis: 15.6 spleen: 2.1 Cell line enhanced HEK 293: 7.7 +ERCC6 ARMD5, CKN2, CSB, RAD26 ENSG00000225830 ERCC excision repair 6, chromatin remodeling factor 10 49455368-49539538 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA071297 Approved Nucleoplasm
Nuclear bodies Mixed Mixed parathyroid gland: 14.9 Expressed in all +LINC00694 ENSG00000225873 Long intergenic non-protein coding RNA 694 3 44421127-44439946 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 8 testis: 28.4 spleen: 3.7 Cell line enhanced HMC-1: 24.5;K-562: 4.3;NB-4: 8.8 +FRG2B ENSG00000225899 FSHD region gene 2 family member B 10 133623895-133626795 Predicted intracellular proteins Evidence at transcript level HPA039264, HPA047769 Uncertain Not detected Not detected kidney: 0.2 Cell line enriched 20 HDLM-2: 7.4 +NOL7 C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1 ENSG00000225921 Nucleolar protein 7 6 13615327-13632739 Predicted intracellular proteins Evidence at protein level HPA029185, HPA049693 Supported Enhanced Nucleus
Nucleoli
Mitochondria Ovarian cancer:3.64e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 92.8 Expressed in all +CTAGE4 cTAGE-4, FLJ43692 ENSG00000225932 CTAGE family member 4 7 144183466-144186053 Predicted membrane proteins Evidence at protein level HPA000387, HPA000922 Uncertain Not detected Tissue enhanced thyroid gland: 16.4 testis: 13.6 Cell line enhanced A-431: 16.9;hTCEpi: 10.1;RPTEC TERT1: 9.9;SiHa: 9.1 +C5orf67 ENSG00000225940 Chromosome 5 open reading frame 67 5 56511567-56606232 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Group enriched 8 epididymis: 19.8;kidney: 9.4 thyroid gland: 1.9 Group enriched 7 CACO-2: 1.7;EFO-21: 5.3;U-266/70: 4.8 +NTF4 GLC1O, NT-4/5, NTF5 ENSG00000225950 Neurotrophin 4 19 49061066-49065054 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level HPA049376 Approved Golgi apparatus Mixed Tissue enhanced skin: 36.6 prostate: 11.4 Cell line enhanced CAPAN-2: 12.1;HaCaT: 27.5;hTCEpi: 36.4 +ELFN1 PPP1R28 ENSG00000225968 Extracellular leucine rich repeat and fibronectin type III domain containing 1 7 1688119-1747954 Predicted membrane proteins Evidence at protein level HPA066382 Approved Nucleoplasm
Cell Junctions Liver cancer:9.68e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 3.5;liver: 3.7 endometrium: 1.7 Cell line enhanced REH: 28.4;U-138 MG: 18.3;U-2 OS: 28.4;U-2197: 29.8 +PIGBOS1 ENSG00000225973 PIGB opposite strand 1 15 55317184-55319161 Predicted intracellular proteins Evidence at transcript level Breast cancer:4.19e-4 (favourable) Expressed in all Expressed in all thyroid gland: 26.2 Expressed in all +CT47A6 CT47.6 ENSG00000226023 Cancer/testis antigen family 47, member A6 X 120958165-120961487 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Not detected testis: 0.5 Not detected +FTCDNL1 FONG ENSG00000226124 Formiminotransferase cyclodeaminase N-terminal like 2 199760544-199851173 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA065748 Uncertain Vesicles Renal cancer:3.31e-4 (favourable), Thyroid cancer:5.74e-4 (unfavourable) Mixed Mixed thyroid gland: 12.0 Mixed +TEX22 ENSG00000226174 Testis expressed 22 14 105398579-105450106 Predicted intracellular proteins Evidence at protein level HPA065576 Enhanced Mixed Tissue enhanced testis: 2.1 cerebral cortex: 0.8 Cell line enhanced HDLM-2: 2.6;U-266/70: 1.7 +OR52I2 ENSG00000226288 Olfactory receptor family 52 subfamily I member 2 11 4586791-4587905 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA049343 Uncertain Not detected Not detected epididymis: 0.2 Not detected +CROCC2 ENSG00000226321 Ciliary rootlet coiled-coil, rootletin family member 2 2 240906330-240993311 Predicted intracellular proteins Evidence at protein level HPA048678 Enhanced Tissue enhanced Group enriched 5 fallopian tube: 8.6;spleen: 3.1 lung: 1.1 Cell line enhanced RPMI-8226: 1.9 +DCAF8L1 WDR42B ENSG00000226372 DDB1 and CUL4 associated factor 8 like 1 X 27977993-27981449 Predicted intracellular proteins Evidence at protein level HPA043787 Enhanced Not detected Tissue enriched 56 testis: 5.5 all non-specific tissues: 0.0 Cell line enriched 16 Karpas-707: 13.4 +USP17L7 ENSG00000226430 Ubiquitin specific peptidase 17-like family member 7 8 12132417-12134438 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +TMEM185B FAM11B, FLJ20979 ENSG00000226479 Transmembrane protein 185B 2 120221278-120223408 Predicted membrane proteins Evidence at protein level HPA048295, HPA071744 Uncertain Approved Endoplasmic reticulum Liver cancer:5.71e-7 (unfavourable), Endometrial cancer:4.96e-6 (unfavourable), Colorectal cancer:5.44e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 62.6 Mixed +AC138647.1 ENSG00000226490 8 141514638-141518737 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced testis: 1.8 skin: 0.3 Not detected +CT47A9 CT47.9 ENSG00000226600 Cancer/testis antigen family 47, member A9 X 120943561-120946883 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 20 testis: 2.0 all non-specific tissues: 0.0 Not detected +KIF4B ENSG00000226650 Kinesin family member 4B 5 155013755-155018132 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034745, HPA034746, HPA061583 Uncertain Enhanced Nucleoplasm Not detected Tissue enriched 63 testis: 6.3 all non-specific tissues: 0.0 Not detected +CT47A12 CT47.12 ENSG00000226685 Cancer/testis antigen family 47, member A12 X 120930250-120932301 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 23 testis: 2.3 all non-specific tissues: 0.0 Not detected +AC005281.1 ENSG00000226690 7 12483344-12541910 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 6 fallopian tube: 8.1;testis: 1.6 lung: 0.7 Cell line enhanced HAP1: 1.4 +RP11-397G17.1 ENSG00000226733 6 50093616-50181007 Predicted intracellular proteins Evidence at transcript level Group enriched Group enriched 8 epididymis: 136.0;kidney: 50.9 liver: 12.3 Not detected +HSBP1L1 FLJ10967, MGC189743 ENSG00000226742 Heat shock factor binding protein 1 like 1 18 79964561-79970822 Predicted intracellular proteins Evidence at transcript level HPA048273 Approved Approved Nucleoplasm Expressed in all Expressed in all colon: 12.2 Cell line enhanced HHSteC: 113.0;SK-MEL-30: 62.5 +TAS2R46 T2R54 ENSG00000226761 Taste 2 receptor member 46 12 11061365-11062294 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +SRRM5 ENSG00000226763 Serine/arginine repetitive matrix 5 19 43596617-43614497 Predicted intracellular proteins Evidence at protein level HPA047399 Uncertain Mixed Tissue enriched 31 testis: 40.1 lymph node: 1.3 Mixed +PGAM4 dJ1000K24.1, PGAM-B, PGAM1, PGAM3 ENSG00000226784 Phosphoglycerate mutase family member 4 X 77968874-77969638 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042528, HPA060483 Uncertain Approved Nucleoplasm Mixed Not detected appendix: 0.5 Cell line enhanced A-431: 1.9 +LINC00371 ENSG00000226792 Long intergenic non-protein coding RNA 371 13 51082119-51200252 Predicted intracellular proteins Evidence at transcript level Tissue enriched Not detected testis: 0.9 Group enriched 99 HAP1: 8.9;NTERA-2: 10.8 +ERVMER34-1 ENSG00000226887 Endogenous retrovirus group MER34 member 1 4 52722618-52751640 Predicted membrane proteins Evidence at protein level HPA011423, HPA024053 Uncertain Approved Nucleus
Cytosol Head and neck cancer:3.55e-4 (unfavourable) Mixed Group enriched 8 parathyroid gland: 48.2;placenta: 15.6 kidney: 3.7 Cell line enhanced CACO-2: 38.7;hTCEpi: 23.6;RPTEC TERT1: 18.4 +CT47A11 CT47.11 ENSG00000226929 Cancer/testis antigen family 47, member A11 X 120933840-120937158 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 37 testis: 3.7 all non-specific tissues: 0.0 Not detected +RBMY1J ENSG00000226941 RNA binding motif protein, Y-linked, family 1, member J Y 22403461-22417881 Predicted intracellular proteins Evidence at protein level HPA001534, HPA053147 Supported Not detected Tissue enriched 17 testis: 2.7 lung: 0.1 Group enriched 138 U-266/70: 18.5;U-266/84: 8.9 +LTA LT, TNFB, TNFSF1 ENSG00000226979 Lymphotoxin alpha 6 31572054-31574324 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level HPA007729 Uncertain Mixed Tissue enhanced lymph node: 1.5 spleen: 0.9 Not detected +C14orf132 C14orf88 ENSG00000227051 Chromosome 14 open reading frame 132 14 96039324-96093889 Predicted membrane proteins Evidence at transcript level Pancreatic cancer:3.54e-4 (favourable), Urothelial cancer:4.95e-4 (unfavourable) Mixed Tissue enhanced cerebral cortex: 82.6 fallopian tube: 35.8 Cell line enhanced SCLC-21H: 62.1;SH-SY5Y: 55.5;U-87 MG: 45.2 +WDR46 BING4, C6orf11, UTP7 ENSG00000227057 WD repeat domain 46 6 33279108-33289527 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043004 Uncertain Renal cancer:4.75e-4 (unfavourable) Expressed in all Tissue enhanced epididymis: 16.5 tonsil: 10.0 Group enriched 29 BEWO: 30.8;HMC-1: 27.8;U-698: 49.4 +ANHX ENSG00000227059 Anomalous homeobox 12 133218312-133236095 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enriched 76 testis: 7.5 all non-specific tissues: 0.0 Not detected +ZNF717 X17, ZNF838 ENSG00000227124 Zinc finger protein 717 3 75709643-75785583 Predicted intracellular proteins Evidence at transcript level HPA044549 Uncertain Approved Nucleoplasm
Nuclear bodies
Plasma membrane Mixed Expressed in all epididymis: 29.3 Cell line enhanced K-562: 73.1 +USP17L5 ENSG00000227140 Ubiquitin specific peptidase 17-like family member 5 4 9339403-9340995 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +PRR20D ENSG00000227151 Proline rich 20D 13 57160632-57163653 Predicted intracellular proteins Evidence at protein level HPA059485 Uncertain Not detected Not detected testis: 0.1 Not detected +SPANXB1 CT11.2, SPANXB2, SPANXF1, SPANXF2 ENSG00000227234 SPANX family member B1 X 141002591-141003706 Predicted intracellular proteins Evidence at protein level HPA046423, HPA073647 Supported Approved Nucleoplasm
Vesicles Mixed Tissue enriched 370 testis: 42.5 kidney: 0.1 Group enriched 26 A-431: 70.8;U-2 OS: 28.0 +KLLN killin ENSG00000227268 Killin, p53-regulated DNA replication inhibitor 10 87859161-87863437 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA074502 Supported Nucleus Mixed Mixed fallopian tube: 2.4 Mixed +PARG ENSG00000227345 Poly(ADP-ribose) glycohydrolase 10 49818279-49970203 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021819, HPA053007 Enhanced Enhanced Nucleus
Vesicles Liver cancer:5.57e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 16.9 Expressed in all +AKR1B15 ENSG00000227471 Aldo-keto reductase family 1 member B15 7 134549136-134579875 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020280, HPA073633 Uncertain Supported Plasma membrane
Cytosol Liver cancer:1.80e-5 (unfavourable), Urothelial cancer:1.90e-5 (unfavourable), Head and neck cancer:8.36e-4 (favourable) Mixed Tissue enriched 13 breast: 179.9 duodenum: 13.7 Group enriched 8 A549: 14.3;HDLM-2: 11.8;Hep G2: 7.6;NTERA-2: 3.2;SK-BR-3: 3.8;U-87 MG: 6.4 +GAGE12D ENSG00000227488 G antigen 12D X 49541767-49549094 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Not detected Tissue enriched 461 testis: 46.0 all non-specific tissues: 0.0 Group enriched 10 U-2 OS: 9.9;U-266/84: 25.6 +SCAMP4 FLJ33847 ENSG00000227500 Secretory carrier membrane protein 4 19 1905214-1926013 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043284 Approved Approved Golgi apparatus
Vesicles
Lipid droplets
Plasma membrane Endometrial cancer:4.40e-6 (favourable), Liver cancer:1.92e-5 (unfavourable), Renal cancer:3.56e-4 (favourable) Expressed in all Expressed in all fallopian tube: 59.3 Expressed in all +LTB p33, TNFC, TNFSF3 ENSG00000227507 Lymphotoxin beta 6 31580525-31582522 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048884 Approved Approved Centrosome Renal cancer:3.31e-7 (unfavourable), Endometrial cancer:2.36e-6 (favourable), Head and neck cancer:1.74e-4 (favourable) Expressed in all Group enriched 7 appendix: 18.6;lymph node: 22.1;spleen: 25.8;tonsil: 10.1 bone marrow: 2.6 Cell line enhanced Daudi: 20.4;HDLM-2: 15.0;NB-4: 11.8;REH: 16.1;U-698: 14.4 +USP17L12 ENSG00000227551 Ubiquitin specific peptidase 17-like family member 12 4 9220152-9221744 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +RD3L TDRD9-AS1, TDRD9AS1 ENSG00000227729 Retinal degeneration 3-like 14 103940426-103942308 Predicted intracellular proteins Evidence at transcript level HPA067971 Uncertain Not detected Tissue enriched 89 heart muscle: 20.8 liver: 0.2 Not detected +C1orf234 ENSG00000227868 Chromosome 1 open reading frame 234 1 23010834-23015850 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 107 testis: 98.0 epididymis: 0.9 Not detected +MRLN Linc-RAM, LINC00948, M1, MLN, MUSER1 ENSG00000227877 Myoregulin 10 59736692-59756041 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Tissue enhanced Tissue enhanced skeletal muscle: 65.4 kidney: 13.8 Cell line enriched 12 RH-30: 21.4 +POLR2J2 RPB11b1 ENSG00000228049 RNA polymerase II subunit J2 7 102665368-102671629 Predicted intracellular proteins Evidence at protein level HPA042997, HPA044010, HPA046970 Uncertain Approved Nucleoplasm Not detected Mixed appendix: 6.6 Cell line enhanced MOLT-4: 17.9;U-2 OS: 14.2 +BOD1L2 BOD1P, FAM44C, MGC33608 ENSG00000228075 Biorientation of chromosomes in cell division 1 like 2 18 57147062-57150300 Predicted intracellular proteins Evidence at transcript level HPA036293 Uncertain Not detected Tissue enriched 4257 testis: 425.7 all non-specific tissues: 0.0 Not detected +IFNA14 IFN-alphaH, LEIF2H ENSG00000228083 Interferon alpha 14 9 21239002-21239991 Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR2M3 OR2M3P, OR2M6, OST003 ENSG00000228198 Olfactory receptor family 2 subfamily M member 3 1 248203068-248204006 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +MT-ATP8 A6L, ATP8, MTATP8 ENSG00000228253 Mitochondrially encoded ATP synthase 8 MT 8366-8572 Disease related genes, Predicted membrane proteins Evidence at protein level Liver cancer:7.56e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 66363.2 Expressed in all +ORM2 AGP-B, AGP-B', AGP2 ENSG00000228278 Orosomucoid 2 9 114329869-114333252 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA046438, HPA047725, HPA057726 Approved Approved Golgi apparatus
Vesicles Renal cancer:1.23e-9 (unfavourable) Tissue enriched Tissue enriched 96 liver: 3772.7 prostate: 39.2 Cell line enriched 195 Hep G2: 567.8 +C19orf24 FLJ20640 ENSG00000228300 Chromosome 19 open reading frame 24 19 1275438-1279249 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043279, HPA047026 Uncertain Approved Nuclear speckles
Golgi apparatus Expressed in all Expressed in all spleen: 36.3 Expressed in all +TSTD3 ENSG00000228439 Thiosulfate sulfurtransferase (rhodanese)-like domain containing 3 6 99520693-99531918 Predicted intracellular proteins Evidence at transcript level Expressed in all Mixed parathyroid gland: 7.4 Mixed +OST4 ENSG00000228474 Oligosaccharyltransferase complex subunit 4, non-catalytic 2 27070472-27071773 Predicted membrane proteins Evidence at protein level Renal cancer:7.35e-5 (unfavourable), Liver cancer:5.11e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 344.8 Expressed in all +LINC01125 ENSG00000228486 Long intergenic non-protein coding RNA 1125 2 97664217-97703064 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced testis: 11.7 skin: 2.4 Cell line enhanced AF22: 1.7;HDLM-2: 1.8 +CT47A7 CT47.7 ENSG00000228517 Cancer/testis antigen family 47, member A7 X 120953288-120956600 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Not detected testis: 0.1 Not detected +VN1R4 V1RL4 ENSG00000228567 Vomeronasal 1 receptor 4 19 53266676-53267723 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA027018 Uncertain Not detected Not detected testis: 0.5 Not detected +NUTM2E FAM22E ENSG00000228570 NUT family member 2E 10 79841358-79850878 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced testis: 1.1 epididymis: 0.6 Cell line enhanced HMC-1: 1.7;NB-4: 1.0 +FNDC10 C1orf233 ENSG00000228594 Fibronectin type III domain containing 10 1 1598012-1600096 Predicted membrane proteins Evidence at protein level Renal cancer:1.11e-4 (favourable) Expressed in all Tissue enhanced adrenal gland: 12.7 cerebral cortex: 9.4 Cell line enhanced HMC-1: 24.9 +CLDN25 ENSG00000228607 Claudin 25 11 113779747-113780500 Predicted membrane proteins No evidence HPA053555 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +ZNF883 ENSG00000228623 Zinc finger protein 883 9 112957722-113050043 Predicted intracellular proteins, Transcription factors Evidence at transcript level Stomach cancer:2.89e-6 (unfavourable), Renal cancer:7.07e-4 (unfavourable) Mixed Not detected cervix, uterine: 0.3 Not detected +PROB1 C5orf65 ENSG00000228672 Proline rich basic protein 1 5 139390592-139395713 Predicted intracellular proteins Evidence at protein level HPA060103 Enhanced Approved Nucleoplasm Cervical cancer:9.26e-4 (favourable) Mixed Tissue enhanced skeletal muscle: 24.8 heart muscle: 6.0 Cell line enriched 6 HDLM-2: 97.1 +ARL17B ARL17 ENSG00000228696 ADP ribosylation factor like GTPase 17B 17 46274784-46361797 Predicted intracellular proteins Evidence at protein level HPA046814 Uncertain Not detected Mixed ovary: 7.6 Mixed +DHFR ENSG00000228716 Dihydrofolate reductase 5 80626228-80654983 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB037129, HPA051465 Uncertain Supported Mitochondria Expressed in all Mixed lymph node: 49.6 Expressed in all +SAPCD1 C6orf26, NG23 ENSG00000228727 Suppressor APC domain containing 1 6 31762799-31764851 Predicted intracellular proteins Evidence at transcript level HPA071699 Approved Vesicles
Cell Junctions Mixed Tissue enhanced skin: 3.2 bone marrow: 1.0 Cell line enhanced HeLa: 2.5 +CT45A5 CT45-5, CT45.5 ENSG00000228836 Cancer/testis antigen family 45 member A5 X 135777130-135785298 Predicted intracellular proteins Evidence at protein level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Not detected Tissue enriched 62 testis: 8.6 cerebral cortex: 0.1 Cell line enhanced HMC-1: 47.9;Karpas-707: 27.5;U-266/84: 147.8 +USP17L30 ENSG00000228856 Ubiquitin specific peptidase 17-like family member 30 4 9363129-9364721 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +TSPY3 CT78 ENSG00000228927 Testis specific protein, Y-linked 3 Y 9398421-9401223 Predicted intracellular proteins Evidence at protein level HPA049384 Supported Not detected Tissue enriched 6 testis: 4.2 epididymis: 0.6 Group enriched 62 U-266/70: 113.3;U-266/84: 101.1 +RPL41 L41 ENSG00000229117 Ribosomal protein L41 12 56116586-56117943 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA053169 Approved Expressed in all Expressed in all ovary: 10643.4 Expressed in all +PGA4 ENSG00000229183 Pepsinogen 4, group I (pepsinogen A) 11 61222216-61231927 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046875 Supported Not detected Tissue enriched 2994 stomach: 34510.3 cerebral cortex: 11.5 Group enriched 7 BJ hTERT+: 12.2;THP-1: 5.2 +RFPL4AL1 ENSG00000229292 Ret finger protein like 4A like 1 19 55769141-55773179 Predicted intracellular proteins Evidence at transcript level HPA046368 Uncertain Approved Centrosome
Cytosol Not detected Not detected spleen: 0.6 Cell line enriched 26 U-2 OS: 27.1 +ORM1 ENSG00000229314 Orosomucoid 1 9 114323056-114326475 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB006265, HPA046438, HPA047725, HPA057726 Approved Approved Golgi apparatus
Vesicles Renal cancer:2.35e-4 (unfavourable) Tissue enriched Tissue enriched 69 liver: 10591.2 bone marrow: 152.4 Cell line enriched 11 Hep G2: 797.0 +SFTA3 NANCI, SFTPH ENSG00000229415 Surfactant associated 3 14 36473288-36513829 Predicted intracellular proteins Evidence at protein level Lung cancer:8.29e-4 (favourable) Group enriched Group enriched 467 lung: 85.7;thyroid gland: 49.2 stomach: 0.1 Cell line enriched 234 SCLC-21H: 23.3 +SPINK8 ENSG00000229453 Serine peptidase inhibitor, Kazal type 8 (putative) 3 48306842-48328341 Predicted secreted proteins Evidence at transcript level HPA053151 Uncertain Breast cancer:8.47e-4 (unfavourable) Group enriched Tissue enriched 7 breast: 58.2 bone marrow: 7.7 Cell line enriched 49 SK-BR-3: 55.0 +PATL2 Pat1a ENSG00000229474 PAT1 homolog 2 15 44665732-44711316 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced lymph node: 20.0;spleen: 19.3 appendix: 10.4 Cell line enriched 30 U-266/70: 95.9 +NKX1-2 bB238F13.2, C10orf121 ENSG00000229544 NK1 homeobox 2 10 124445239-124450184 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA029367 Uncertain Tissue enhanced Not detected cerebral cortex: 0.7 Cell line enhanced HaCaT: 4.8;hTCEpi: 3.7;NTERA-2: 10.3;SCLC-21H: 5.3 +TSPY8 ENSG00000229549 Testis specific protein, Y-linked 8 Y 9357797-9360599 Predicted intracellular proteins Evidence at protein level HPA049384 Supported Not detected Tissue enriched 13 testis: 1.3 all non-specific tissues: 0.0 Cell line enriched 228 U-266/84: 191.8 +PRAMEF25 ENSG00000229571 PRAME family member 25 1 13068677-13077884 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +USP17L26 ENSG00000229579 Ubiquitin specific peptidase 17-like family member 26 4 9334658-9336609 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +PRAC2 C17orf93, HOXB-AS5, HOXB13-AS1, NCRNA00253 ENSG00000229637 Prostate cancer susceptibility candidate 2 17 48723168-48724758 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Tissue enriched Tissue enhanced prostate: 16.8;rectum: 10.1 colon: 4.5 Group enriched 5 PC-3: 44.6;REH: 17.6 +PRR20C ENSG00000229665 Proline rich 20C 13 57140918-57157082 Predicted intracellular proteins Evidence at protein level HPA059485 Uncertain Not detected Not detected testis: 0.3 Not detected +ZNF492 KIAA1473, ZNF115 ENSG00000229676 Zinc finger protein 492 19 22634324-22667670 Predicted intracellular proteins, Transcription factors Evidence at transcript level Group enriched Tissue enhanced testis: 3.6 bone marrow: 1.6 Cell line enhanced BEWO: 5.4;NTERA-2: 4.1;U-2197: 3.7 +ZNF688 ENSG00000229809 Zinc finger protein 688 16 30569346-30572734 Predicted intracellular proteins Evidence at transcript level HPA048922 Uncertain Approved Nucleoplasm
Plasma membrane
Cell Junctions Endometrial cancer:4.58e-5 (favourable), Lung cancer:3.24e-4 (favourable), Breast cancer:5.90e-4 (favourable), Pancreatic cancer:6.61e-4 (favourable), Cervical cancer:7.74e-4 (favourable) Expressed in all Expressed in all testis: 23.7 Expressed in all +PET100 C19orf79 ENSG00000229833 PET100 homolog 19 7629737-7631956 Predicted intracellular proteins Evidence at protein level HPA067288 Approved Nucleoplasm
Mitochondria Urothelial cancer:2.44e-4 (favourable), Cervical cancer:6.81e-4 (favourable), Lung cancer:7.97e-4 (favourable) Expressed in all Expressed in all adrenal gland: 54.6 Expressed in all +PGA3 ENSG00000229859 Pepsinogen 3, group I (pepsinogen A) 11 61203307-61213098 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026358, HPA046875 Enhanced Tissue enriched Tissue enriched 716 stomach: 6775.4 cerebral cortex: 9.4 Group enriched 5 HMC-1: 7.5;THP-1: 1.9 +GK3P GKP3, GKTB ENSG00000229894 Glycerol kinase 3 pseudogene 4 165277812-165279679 Enzymes, Predicted membrane proteins Evidence at transcript level HPA060687 Uncertain Not detected Tissue enriched 79 testis: 23.9 bone marrow: 0.3 Not detected +FAM90A26 FAM90A26P ENSG00000229924 Family with sequence similarity 90 member A26 4 9170409-9176730 Predicted intracellular proteins No evidence Not detected Not detected cerebral cortex: 0.2 Not detected +PRPS1L1 PRPS3, PRPSL ENSG00000229937 Phosphoribosyl pyrophosphate synthetase 1-like 1 7 18026774-18027863 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 575 testis: 57.5 all non-specific tissues: 0.0 Not detected +IQCF3 ENSG00000229972 IQ motif containing F3 3 51817604-51830856 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 242 testis: 72.6 epididymis: 0.3 Not detected +POTEB2 ENSG00000230031 POTE ankyrin domain family member B2 15 20835372-20866314 Predicted intracellular proteins Evidence at transcript level HPA042822 Uncertain Not detected Tissue enriched 40 testis: 3.9 all non-specific tissues: 0.0 Not detected +RP11-402G3.5 ENSG00000230054 9 114656304-114662374 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 115 testis: 56.5 appendix,skin: 0.4 Cell line enhanced Karpas-707: 1.3 +ANKRD66 ENSG00000230062 Ankyrin repeat domain 66 6 46746917-46759506 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enriched 13 fallopian tube: 64.0 lung: 4.9 Not detected +ACBD6 MGC2404 ENSG00000230124 Acyl-CoA binding domain containing 6 1 180269653-180502954 Predicted intracellular proteins Evidence at protein level HPA028179, HPA028457 Approved Approved Nucleoplasm
Cytosol Renal cancer:4.02e-7 (unfavourable) Expressed in all Expressed in all testis: 42.1 Expressed in all +OR4F3 ENSG00000230178 Olfactory receptor family 4 subfamily F member 3 5 181367268-181368262 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047705 Uncertain Not detected Not detected testis: 0.5 Not detected +NFE4 NF-E4 ENSG00000230257 Nuclear factor, erythroid 4 7 102973437-102988856 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 7 placenta: 25.4 testis: 3.7 Cell line enhanced BEWO: 36.5;HUVEC TERT2: 39.4 +SSU72P8 ENSG00000230268 SSU72 pseudogene 8 7 124476371-124476955 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 26 testis: 2.5 all non-specific tissues: 0.0 Not detected +OR5H6 ENSG00000230301 Olfactory receptor family 5 subfamily H member 6 (gene/pseudogene) 3 98264244-98265356 Predicted membrane proteins No evidence Not detected Not detected testis: 0.1 Not detected +CT47A8 CT47.8 ENSG00000230347 Cancer/testis antigen family 47, member A8 X 120948422-120951744 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 20 testis: 2.0 all non-specific tissues: 0.0 Not detected +USP17L25 ENSG00000230430 Ubiquitin specific peptidase 17-like family member 25 4 9329911-9331862 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +ANKRD18B bA255A11.3 ENSG00000230453 Ankyrin repeat domain 18B 9 33524394-33573009 Predicted intracellular proteins Evidence at protein level HPA046346, HPA046695, HPA049923, HPA051288 Uncertain Approved Nucleoli
Cytosol Mixed Tissue enhanced testis: 6.4 skin: 2.8 Cell line enhanced NB-4: 17.4 +PPP5D1 ENSG00000230510 PPP5 tetratricopeptide repeat domain containing 1 19 46480796-46601200 Predicted intracellular proteins Evidence at transcript level HPA073186 Uncertain Uncertain Cytosol Not detected Mixed cerebral cortex: 4.8 Mixed +MBD3L2 ENSG00000230522 Methyl-CpG binding domain protein 3 like 2 19 7049321-7051735 Predicted intracellular proteins Evidence at transcript level HPA051259 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +USP17L1 USP17L1P ENSG00000230549 Ubiquitin specific peptidase 17-like family member 1 8 7332387-7333979 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected cerebral cortex: 0.3 Not detected +CCDC192 LINC01183 ENSG00000230561 Coiled-coil domain containing 192 5 127703389-127941634 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 21 testis: 20.7 skeletal muscle: 0.9 Cell line enhanced AF22: 2.3 +CT47A4 CT47.4 ENSG00000230594 Cancer/testis antigen family 47, member A4 X 120967886-120971208 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 20 testis: 2.0 all non-specific tissues: 0.0 Not detected +RP11-402G3.3 ENSG00000230601 9 114666434-114682066 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 234 testis: 28.7 appendix: 0.1 Cell line enriched 8 Karpas-707: 4.7 +RP11-286H14.4 ENSG00000230626 7 129126518-129130793 Predicted intracellular proteins Evidence at protein level HPA051993 Uncertain Approved Cytosol Mixed Tissue enriched 51 testis: 5.0 all non-specific tissues: 0.0 Not detected +PRB4 ENSG00000230657 Proline rich protein BstNI subfamily 4 12 11307083-11310435 Predicted secreted proteins Evidence at transcript level Group enriched Tissue enriched 3551 salivary gland: 1351.8 skin,testis: 0.3 Cell line enriched 23 CACO-2: 2.2 +SETSIP SETP18 ENSG00000230667 SET-like protein 1 92074533-92075441 Predicted intracellular proteins Evidence at protein level HPA063683 Approved Supported Nucleoplasm
Lipid droplets Mixed Not detected testis: 0.4 Not detected +ANKRD63 ENSG00000230778 Ankyrin repeat domain 63 15 40281444-40282586 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 6 cerebral cortex: 1.0 fallopian tube,kidney,spleen,testis: 0.1 Cell line enhanced HEK 293: 1.8 +YY2 ZNF631 ENSG00000230797 YY2 transcription factor X 21855987-21858727 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001119, HPA030335 Enhanced Approved Nuclear bodies Mixed Tissue enhanced testis: 10.9 endometrium: 2.8 Mixed +STMND1 FLJ23152 ENSG00000230873 Stathmin domain containing 1 6 17102258-17131372 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA067970 Enhanced Approved Actin filaments Group enriched Tissue enhanced fallopian tube: 33.7;testis: 12.3 gallbladder: 9.4 Group enriched 6 HEK 293: 2.6;SCLC-21H: 7.8;T-47d: 7.6 +HSBP1 ENSG00000230989 Heat shock factor binding protein 1 16 83807843-83819737 Predicted intracellular proteins Evidence at protein level Ovarian cancer:2.96e-4 (favourable), Endometrial cancer:5.73e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 58.8 Expressed in all +USP17L28 ENSG00000231051 Ubiquitin specific peptidase 17-like family member 28 4 9348893-9350485 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP21-3 ENSG00000231068 Keratin associated protein 21-3 21 30718525-30718777 Predicted intracellular proteins No evidence HPA046554 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR5H1 HSHTPCRX14, HTPCRX14 ENSG00000231192 Olfactory receptor family 5 subfamily H member 1 3 98132698-98133639 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +PLSCR5 ENSG00000231213 Phospholipid scramblase family member 5 3 146576555-146606216 Predicted membrane proteins Evidence at transcript level HPA047249 Uncertain Not detected Tissue enriched 7 parathyroid gland: 1.8 testis: 0.2 Not detected +C17orf105 ENSG00000231256 Chromosome 17 open reading frame 105 17 43780435-43787612 Predicted intracellular proteins Evidence at transcript level HPA053028 Approved Not detected Tissue enriched 47 testis: 20.2 skin: 0.4 Not detected +SBK3 SgK110 ENSG00000231274 SH3 domain binding kinase family member 3 19 55540656-55545543 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA078322 Approved Mitochondria Not detected Tissue enriched 6 heart muscle: 17.8 adipose tissue: 2.7 Cell line enhanced A549: 4.5;CACO-2: 1.4;CAPAN-2: 2.6;RH-30: 2.1 +HLA-DPA1 HLA-DP1A ENSG00000231389 Major histocompatibility complex, class II, DP alpha 1 6 33064569-33080775 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017967 Enhanced Supported Vesicles Expressed in all Expressed in all lung: 120.6 Cell line enhanced Daudi: 26.7;HDLM-2: 107.3;REH: 26.8 +USP17L10 ENSG00000231396 Ubiquitin specific peptidase 17-like family member 10 4 9210657-9212608 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +RPS18 D6S218E, HKE3, KE-3, KE3, S18 ENSG00000231500 Ribosomal protein S18 6 33272010-33276510 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050159, HPA055007 Approved Supported Cytosol Renal cancer:1.15e-10 (unfavourable), Breast cancer:9.81e-4 (favourable) Expressed in all Expressed in all ovary: 1305.1 Expressed in all +USP17L29 ENSG00000231637 Ubiquitin specific peptidase 17-like family member 29 4 9353638-9355230 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +DIRC3 FLJ14199 ENSG00000231672 Disrupted in renal carcinoma 3 2 217284019-217756593 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced parathyroid gland: 1.3 testis: 0.7 Not detected +TSPAN19 ENSG00000231738 Tetraspanin 19 12 85014311-85036277 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA057066 Uncertain Not detected Tissue enhanced testis: 8.1 lung: 4.3 Cell line enhanced SCLC-21H: 3.1 +AKAIN1 C18orf42 ENSG00000231824 A-kinase anchor inhibitor 1 18 5145285-5197503 Predicted intracellular proteins Evidence at protein level HPA049365 Uncertain Not detected Tissue enriched 11 adrenal gland: 20.1 testis: 1.7 Cell line enhanced SCLC-21H: 1.1 +CYP21A2 CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B ENSG00000231852 Cytochrome P450 family 21 subfamily A member 2 6 32038265-32041670 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA048979, HPA053371 Enhanced Tissue enhanced Tissue enriched 257 adrenal gland: 266.4 epididymis: 1.0 Group enriched 5 HDLM-2: 6.1;Karpas-707: 1.2 +OR5K2 ENSG00000231861 Olfactory receptor family 5 subfamily K member 2 3 98497604-98498663 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected lung,skeletal muscle,skin,spleen: 0.3 Not detected +PRH1 Pa ENSG00000231887 Proline rich protein HaeIII subfamily 1 12 10824960-11171544 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 2295 salivary gland: 17934.0 ovary: 7.8 Cell line enhanced CAPAN-2: 1.6 +PSG1 CD66f, PBG1, PSBG1, PSGGA ENSG00000231924 Pregnancy specific beta-1-glycoprotein 1 19 42866464-42879822 CD markers, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046327 Approved Tissue enhanced Tissue enriched 377 placenta: 362.6 smooth muscle,spleen: 0.9 Cell line enriched 23 U-2197: 384.6 +TAPBP TAPA ENSG00000231925 TAP binding protein 6 33299694-33314387 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007066 Approved Breast cancer:2.76e-4 (favourable), Melanoma:6.29e-4 (favourable) Expressed in all Expressed in all spleen: 30.7 Cell line enhanced CAPAN-2: 67.6 +PPP1R2P3 MGC87149 ENSG00000231989 Protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 3 5 156850538-156852528 Predicted intracellular proteins Evidence at transcript level HPA043729, HPA059420 Approved Nucleoplasm
Cytosol Not detected Tissue enriched 435 testis: 43.5 all non-specific tissues: 0.0 Not detected +MAGEB6P1 MAGEB6B ENSG00000232030 MAGE family member B6 pseudogene 1 X 26160601-26161824 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.8 Not detected +ZBED9 Buster4, FLJ31087, KIAA1925, SCAND3, ZFP38-L, ZNF305P2, ZNF452 ENSG00000232040 Zinc finger BED-type containing 9 6 28571630-28616212 Predicted intracellular proteins Evidence at protein level HPA007246 Uncertain Approved Nucleus
Nucleoli
Golgi apparatus Mixed Tissue enhanced testis: 18.8 epididymis: 4.6 Cell line enhanced EFO-21: 5.6;K-562: 9.2 +TMEM253 C14orf176, C14orf95, NCRNA00220 ENSG00000232070 Transmembrane protein 253 14 21098937-21103724 Predicted membrane proteins Evidence at protein level HPA052329, HPA065092 Enhanced Mixed Group enriched 6 duodenum: 101.3;small intestine: 100.0 colon: 15.8 Mixed +TMA7 CCDC72, HSPC016 ENSG00000232112 Translation machinery associated 7 homolog 3 48440257-48444208 Predicted intracellular proteins Evidence at protein level HPA047397 Approved Nucleus
Nucleoli
Nuclear bodies Lung cancer:8.33e-4 (favourable) Expressed in all Expressed in all epididymis: 420.1 Expressed in all +RP11-360D2.1 ENSG00000232113 1 173635333-173637134 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 244 testis: 24.4 all non-specific tissues: 0.0 Not detected +MCTS1 MCT-1 ENSG00000232119 MCTS1, re-initiation and release factor X 120594010-120621074 Predicted intracellular proteins Evidence at protein level HPA001045 Supported Plasma membrane
Cytosol Head and neck cancer:3.27e-5 (unfavourable), Renal cancer:4.35e-5 (unfavourable), Breast cancer:1.38e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 50.7 Expressed in all +DYTN ENSG00000232125 Dystrotelin 2 206651621-206718396 Predicted intracellular proteins Evidence at protein level Not detected Not detected bone marrow,testis: 0.1 Not detected +MTRNR2L4 ENSG00000232196 MT-RNR2-like 4 16 3370979-3372740 Predicted intracellular proteins Evidence at transcript level Not detected Expressed in all skeletal muscle: 98.2 Cell line enhanced AN3-CA: 43.4;HaCaT: 43.7;HeLa: 44.1 +ASCL5 bHLHa47 ENSG00000232237 Achaete-scute family bHLH transcription factor 5 1 201113953-201127184 Predicted intracellular proteins, Transcription factors No evidence Mixed Not detected endometrium: 0.6 Not detected +TMEM114 ENSG00000232258 Transmembrane protein 114 16 8537605-8590193 Disease related genes, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 61 seminal vesicle: 28.7 epididymis: 0.4 Not detected +KRTAP25-1 KAP25.1 ENSG00000232263 Keratin associated protein 25-1 21 30289145-30289514 Predicted intracellular proteins No evidence HPA031438 Uncertain Approved Nuclear membrane
Plasma membrane
Cytosol Not detected Not detected all non-specific tissues: 0.0 Not detected +USP17L24 ENSG00000232264 Ubiquitin specific peptidase 17-like family member 24 4 9325165-9327116 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +OR52I1 ENSG00000232268 Olfactory receptor family 52 subfamily I member 1 11 4593750-4595013 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR5K1 HSHTPCRX10, HTPCRX10 ENSG00000232382 Olfactory receptor family 5 subfamily K member 1 3 98469480-98470576 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +LINC00493 LOC388789 ENSG00000232388 Long intergenic non-protein coding RNA 493 20 18567347-18569563 Predicted membrane proteins Evidence at transcript level HPA068733 Approved Nucleoplasm
Cytosol Urothelial cancer:7.84e-5 (favourable) Expressed in all Expressed in all epididymis: 157.9 Expressed in all +USP17L13 ENSG00000232399 Ubiquitin specific peptidase 17-like family member 13 4 9224896-9226847 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +PRAMEF6 ENSG00000232423 PRAME family member 6 1 12938472-12947580 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +C9orf172 ENSG00000232434 Chromosome 9 open reading frame 172 9 136844415-136848801 Predicted intracellular proteins Evidence at protein level HPA021200 Uncertain Approved Focal adhesion sites
Cytosol Expressed in all Tissue enhanced cerebral cortex: 7.4 spleen: 3.3 Mixed +KANTR LINC01155, Spasm ENSG00000232593 KDM5C adjacent non-coding transcript X 53094145-53170914 Predicted secreted proteins Evidence at transcript level Mixed Tissue enriched 5 cerebral cortex: 2.3 bone marrow: 0.4 Not detected +HLA-DQB2 HLA-DXB ENSG00000232629 Major histocompatibility complex, class II, DQ beta 2 6 32756098-32763534 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Breast cancer:5.55e-4 (favourable) Expressed in all Tissue enhanced lung: 8.1;skin: 13.3 tonsil: 5.9 Not detected +GOLGA8N ENSG00000232653 Golgin A8 family member N 15 32593456-32607310 Predicted intracellular proteins Evidence at transcript level Mixed Expressed in all thyroid gland: 26.0 Group enriched 6 HEL: 71.9;THP-1: 35.0;U-937: 53.1 +TNF DIF, TNF-alpha, TNFA, TNFSF2 ENSG00000232810 Tumor necrosis factor 6 31575567-31578336 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced bone marrow: 3.7 lymph node: 1.3 Group enriched 5 HDLM-2: 13.9;HMC-1: 12.0;NB-4: 27.3 +PET117 CSRP2BP ENSG00000232838 PET117 homolog 20 18137873-18143169 Predicted secreted proteins Evidence at protein level HPA047716 Approved Liver cancer:4.76e-6 (unfavourable), Renal cancer:4.15e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 24.1 Expressed in all +LYRM9 C17orf108, HSD24 ENSG00000232859 LYR motif containing 9 17 27878314-27894752 Predicted intracellular proteins Evidence at protein level HPA023051 Uncertain Renal cancer:5.41e-4 (favourable), Pancreatic cancer:9.46e-4 (favourable) Mixed Expressed in all thyroid gland: 71.9 Cell line enhanced T-47d: 25.0 +DEFB130 DEFB-30, DEFB30 ENSG00000232948 Defensin beta 130 8 12310962-12318316 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 47 epididymis: 4.7 all non-specific tissues: 0.0 Not detected +RP11-1212A22.4 ENSG00000233024 16 18358086-18379331 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Uncertain Nucleoplasm Not detected Expressed in all parathyroid gland: 131.8 Expressed in all +PHGR1 ENSG00000233041 Proline, histidine and glycine rich 1 15 40351033-40356434 Predicted intracellular proteins Evidence at protein level HPA068787 Enhanced Approved Vesicles Breast cancer:2.05e-4 (favourable) Group enriched Group enriched 7 colon: 1448.4;duodenum: 892.1;rectum: 399.5;small intestine: 1777.5 stomach: 166.8 Cell line enhanced BEWO: 12.3;HaCaT: 16.0;SCLC-21H: 72.5 +RP11-1236K1.1 ENSG00000233050 8 12064389-12071747 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 47 epididymis: 4.7 all non-specific tissues: 0.0 Not detected +WTH3DI ENSG00000233087 RAB6C-like 2 131361111-131364142 Predicted intracellular proteins Evidence at protein level HPA059131 Uncertain Approved Golgi apparatus Tissue enhanced Tissue enriched 6 parathyroid gland: 14.4 prostate: 2.3 Cell line enhanced MOLT-4: 1.7 +USP17L11 ENSG00000233136 Ubiquitin specific peptidase 17-like family member 11 4 9215405-9217356 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected thyroid gland: 0.2 Not detected +RNF224 ENSG00000233198 Ring finger protein 224 9 137227271-137229638 Predicted intracellular proteins Evidence at transcript level Mixed Mixed esophagus: 1.1 Cell line enhanced CAPAN-2: 4.5;MCF7: 7.0 +NPIPB7 LOC440350, NPIPL1 ENSG00000233232 Nuclear pore complex interacting protein family member B7 16 28456372-28471175 Predicted membrane proteins Evidence at protein level HPA011188, HPA053611 Approved Approved Nucleoplasm Not detected Tissue enriched 32 testis: 15.3 skin: 0.4 Cell line enhanced BEWO: 1.7 +GPX1 ENSG00000233276 Glutathione peroxidase 1 3 49357176-49358600 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011582, HPA044758 Approved Supported Cytosol Endometrial cancer:7.78e-4 (favourable) Expressed in all Expressed in all adipose tissue: 276.3 Mixed +OR5H15 ENSG00000233412 Olfactory receptor family 5 subfamily H member 15 3 98168700-98169733 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +BTBD18 ENSG00000233436 BTB domain containing 18 11 57743514-57751781 Predicted intracellular proteins Evidence at protein level HPA049325 Uncertain Not detected Tissue enriched 8 testis: 4.0 skin: 0.5 Not detected +TMEM238 ENSG00000233493 Transmembrane protein 238 19 55379245-55384598 Predicted membrane proteins Evidence at protein level Renal cancer:8.84e-6 (favourable) Expressed in all Tissue enhanced small intestine: 10.0;stomach: 9.9 colon: 9.1 Cell line enhanced A-431: 17.0;HaCaT: 15.4 +TWIST2 bHLHa39, Dermo-1, DERMO1 ENSG00000233608 Twist family bHLH transcription factor 2 2 238848032-238910543 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062870 Supported Nucleus
Nucleoli Mixed Tissue enhanced cervix, uterine: 40.1 adipose tissue: 27.3 Cell line enhanced ASC diff: 104.1;BJ: 108.5;BJ hTERT+: 326.5;fHDF/TERT166: 143.5;U-2197: 143.4 +PIRT ENSG00000233670 Phosphoinositide interacting regulator of transient receptor potential channels 17 10822475-10838445 Predicted membrane proteins, Transporters Evidence at transcript level HPA042337 Uncertain Uncertain Plasma membrane
Cytosol Tissue enriched Tissue enhanced adrenal gland: 3.1;cerebral cortex: 2.6;rectum: 2.7 colon: 2.1 Not detected +PRR23C FLJ46210 ENSG00000233701 Proline rich 23C 3 139042102-139044892 Predicted intracellular proteins Evidence at transcript level HPA047473 Uncertain Not detected Tissue enriched 12 testis: 1.7 cerebral cortex,skin,spleen: 0.1 Not detected +MYCNOS MYCN-AS1, N-CYM, NCYM ENSG00000233718 MYCN opposite strand 2 15939898-15941723 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enhanced testis: 3.9 cerebral cortex: 1.2 Cell line enhanced BEWO: 17.5;HMC-1: 5.0;NTERA-2: 4.2 +AC092835.2 ENSG00000233757 2 95207535-95259774 Predicted intracellular proteins Evidence at transcript level Mixed Mixed testis: 3.9 Cell line enhanced SCLC-21H: 6.3 +TRIM49D2 TRIM49D2P, TRIM49L, TRIM49L1 ENSG00000233802 Tripartite motif containing 49D2 11 89924064-89933063 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.2 Not detected +TSPY4 ENSG00000233803 Testis specific protein, Y-linked 4 Y 9337464-9340284 Predicted intracellular proteins Evidence at protein level HPA049384 Supported Not detected Tissue enriched 205 testis: 62.6 spleen: 0.3 Group enriched 498 U-266/70: 1493.8;U-266/84: 1550.5 +IFNA13 ENSG00000233816 Interferon alpha 13 9 21367424-21368962 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected epididymis: 0.5 Not detected +HIST1H2BN H2B/d, H2BFD ENSG00000233822 Histone cluster 1 H2B family member n 6 27837760-27865798 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed Mixed testis: 3.3 Cell line enhanced SCLC-21H: 8.5 +POTEB A26B1, CT104.5, POTE-15, POTE15 ENSG00000233917 POTE ankyrin domain family member B 15 21846329-21877703 Predicted intracellular proteins Evidence at transcript level HPA042822 Uncertain Not detected Tissue enriched 10 testis: 1.0 all non-specific tissues: 0.0 Not detected +RPS28 S28 ENSG00000233927 Ribosomal protein S28 19 8321158-8323340 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047132 Approved Approved Cytosol Endometrial cancer:2.47e-4 (favourable) Expressed in all Expressed in all ovary: 306.5 Expressed in all +CTXN2 ENSG00000233932 Cortexin 2 15 48191539-48203756 Predicted membrane proteins Evidence at transcript level HPA053168 Uncertain Not detected Group enriched 8 cerebral cortex: 1.9;testis: 1.5 fallopian tube: 0.2 Not detected +UQCRHL ENSG00000233954 Ubiquinol-cytochrome c reductase hinge protein like 1 15807169-15809348 Predicted intracellular proteins Evidence at protein level HPA042574 Approved Expressed in all Mixed skin: 1.3 Not detected +PAGE2 CT16.4, GAGEC2, MGC62094, PAGE-2 ENSG00000234068 PAGE family member 2 X 55089008-55092842 Predicted intracellular proteins Evidence at protein level HPA052619 Supported Mixed Tissue enriched 42 testis: 43.8 placenta: 1.0 Group enriched 444 U-2 OS: 260.7;U-266/70: 782.4;U-266/84: 993.0 +TRIM26 RNF95, ZNF173 ENSG00000234127 Tripartite motif containing 26 6 30184455-30213427 Predicted intracellular proteins Evidence at protein level HPA044975, HPA050456 Approved Supported Nucleoplasm
Cytosol Urothelial cancer:3.25e-5 (favourable) Expressed in all Mixed fallopian tube: 10.4 Mixed +C16orf82 TNT ENSG00000234186 Chromosome 16 open reading frame 82 16 27066707-27069165 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 3011 testis: 301.0 all non-specific tissues: 0.0 Not detected +TMEM229A ENSG00000234224 Transmembrane protein 229A 7 124030916-124033023 Predicted membrane proteins Evidence at protein level HPA056391 Uncertain Approved Plasma membrane Tissue enhanced Tissue enhanced cerebral cortex: 7.1;duodenum: 8.6;testis: 10.4 small intestine: 4.4 Cell line enriched 46 SH-SY5Y: 141.7 +PRR20E ENSG00000234278 Proline rich 20E 13 57167197-57170218 Predicted intracellular proteins Evidence at protein level HPA059485 Uncertain Not detected Not detected testis: 0.1 Not detected +ZNF879 DKFZp686E2433 ENSG00000234284 Zinc finger protein 879 5 179023752-179035064 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA068608 Uncertain Approved Nucleus Mixed Mixed testis: 11.3 Mixed +H2BFS ENSG00000234289 H2B histone family member S 21 43565189-43565648 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Not detected Mixed prostate: 8.2 Cell line enhanced K-562: 40.6;U-2 OS: 43.9;U-266/84: 32.4 +CCDC188 ENSG00000234409 Coiled-coil domain containing 188 22 20148427-20151065 Predicted membrane proteins Evidence at transcript level HPA049901 Approved Nucleoplasm
Nuclear bodies Mixed Tissue enriched 10 testis: 18.1 spleen: 1.8 Cell line enhanced AF22: 4.0;SCLC-21H: 6.6;SH-SY5Y: 7.6 +RBMY1A1 RBM1, RBM2, YRRM1, YRRM2 ENSG00000234414 RNA binding motif protein, Y-linked, family 1, member A1 Y 21511372-21549326 Predicted intracellular proteins Evidence at protein level HPA001534, HPA053147 Supported Not detected Tissue enriched 161 testis: 17.5 kidney,placenta: 0.1 Cell line enriched 9 U-266/84: 10.5 +KBTBD13 hCG_1645727, NEM6 ENSG00000234438 Kelch repeat and BTB domain containing 13 15 65076816-65078192 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA062737 Uncertain Not detected Tissue enriched 12 skeletal muscle: 5.2 heart muscle: 0.4 Not detected +ZNF736 ENSG00000234444 Zinc finger protein 736 7 64307459-64354860 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051027, HPA061215 Uncertain Uncertain Nucleoplasm Endometrial cancer:3.03e-4 (unfavourable), Prostate cancer:5.01e-4 (unfavourable), Urothelial cancer:8.65e-4 (favourable) Mixed Mixed testis: 15.1 Mixed +PINLYP ENSG00000234465 Phospholipase A2 inhibitor and LY6/PLAUR domain containing 19 43576800-43583964 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA061218 Uncertain Approved Vesicles Mixed Mixed fallopian tube: 27.7 Cell line enhanced HEL: 65.4;HMC-1: 40.9;REH: 27.1;THP-1: 24.6 +CLDN34 ENSG00000234469 Claudin 34 X 9967358-9968352 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 13 testis: 2.3 epididymis,kidney,ovary,placenta,prostate,skin,urinary bladder: 0.1 Not detected +C5orf58 ENSG00000234511 Chromosome 5 open reading frame 58 5 170232447-170252575 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enriched 88 testis: 372.5 bone marrow: 4.2 Cell line enriched 9 U-266/84: 53.7 +FAM133B MGC40405 ENSG00000234545 Family with sequence similarity 133 member B 7 92560793-92590394 Predicted intracellular proteins Evidence at protein level HPA066175, HPA069513 Approved Nucleus
Nucleoli Expressed in all Expressed in all epididymis: 34.6 Expressed in all +OR10G8 ENSG00000234560 Olfactory receptor family 10 subfamily G member 8 11 124029590-124030634 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +MCIDAS IDAS, MCI, MCIN ENSG00000234602 Multiciliate differentiation and DNA synthesis associated cell cycle protein 5 55219614-55227315 Predicted intracellular proteins Evidence at protein level HPA049981, HPA058073 Uncertain Supported Nuclear bodies Mixed Not detected fallopian tube,gallbladder,parathyroid gland,stomach,testis,thyroid gland: 0.1 Cell line enhanced BEWO: 2.2;CACO-2: 2.3;HEK 293: 2.0 +JRK jerky, JH8 ENSG00000234616 Jrk helix-turn-helix protein 8 142657460-142681968 Predicted intracellular proteins Evidence at transcript level HPA052675 Approved Nucleus
Nucleoli
Nuclear bodies Expressed in all Mixed testis: 10.9 Expressed in all +NPIPB2 ENSG00000234719 Nuclear pore complex interacting protein family, member B2 16 11927373-11976643 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Supported Approved Nucleoplasm Mixed Tissue enhanced testis: 14.8 parathyroid gland: 8.8 Cell line enhanced RPMI-8226: 10.3;U-266/70: 19.3 +HLA-B AS ENSG00000234745 Major histocompatibility complex, class I, B 6 31269491-31357188 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB015418 Enhanced Melanoma:2.90e-4 (favourable) Expressed in all Mixed lung: 1241.8 Cell line enhanced A-431: 553.0;EFO-21: 516.7;U-266/70: 1064.3 +C11orf94 ENSG00000234776 Chromosome 11 open reading frame 94 11 45906513-45907282 Predicted secreted proteins Evidence at transcript level Mixed Tissue enriched 55 testis: 20.7 esophagus,thyroid gland: 0.3 Cell line enhanced HEK 293: 1.1 +RP11-526A4.1 ENSG00000234828 4 149351903-149896233 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 20 testis: 8.3 rectum: 0.4 Not detected +IFNA17 IFN-alphaI, LEIF2C1 ENSG00000234829 Interferon alpha 17 9 21227243-21228222 Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +APOC2 ENSG00000234906 Apolipoprotein C2 19 44945982-44949565 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA055877 Supported Tissue enriched Tissue enriched 59 liver: 4214.4 small intestine: 71.0 Cell line enhanced Hep G2: 463.1;HMC-1: 196.0;THP-1: 841.9 +SHISA8 C22orf17, Orf26 ENSG00000234965 Shisa family member 8 22 41909554-41914667 Predicted membrane proteins Evidence at transcript level HPA059173 Uncertain Endometrial cancer:2.76e-4 (favourable) Mixed Tissue enhanced adrenal gland: 4.3 lymph node,spleen: 1.4 Cell line enriched 7 HEK 293: 17.7 +C19orf81 ENSG00000235034 Chromosome 19 open reading frame 81 19 50649445-50659310 Predicted intracellular proteins Evidence at protein level HPA060238 Enhanced Approved Vesicles
Aggresome Tissue enhanced Tissue enriched 11 testis: 5.3 cerebral cortex,epididymis,prostate: 0.4 Cell line enhanced HEK 293: 4.0;HMC-1: 1.3 +ANKRD65 ENSG00000235098 Ankyrin repeat domain 65 1 1418420-1421769 Predicted intracellular proteins Evidence at protein level HPA065720 Enhanced Approved Nucleoplasm Lung cancer:1.08e-5 (favourable) Expressed in all Tissue enhanced fallopian tube: 60.0 seminal vesicle: 31.4 Group enriched 8 Hep G2: 24.2;RT4: 27.5;SCLC-21H: 54.5 +LINC00094 bA374P20.3, FLJ35348, NCRNA00094 ENSG00000235106 Long intergenic non-protein coding RNA 94 9 134025439-134034666 Predicted intracellular proteins Evidence at transcript level Renal cancer:4.24e-5 (favourable), Urothelial cancer:2.31e-4 (unfavourable) Expressed in all Mixed fallopian tube: 36.6 Expressed in all +ZSCAN31 ZNF310P, ZNF323 ENSG00000235109 Zinc finger and SCAN domain containing 31 6 28324693-28356271 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007124 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.19e-5 (favourable) Expressed in all Expressed in all testis: 38.7 Cell line enhanced EFO-21: 37.9;U-2 OS: 50.9 +AC010731.4 ENSG00000235118 2 206642418-206649449 Predicted intracellular proteins No evidence Not detected Not detected cerebral cortex: 0.6 Not detected +C12orf75 AGD3, OCC-1, OCC1 ENSG00000235162 Chromosome 12 open reading frame 75 12 105235290-105396097 Predicted intracellular proteins Evidence at protein level HPA065311 Uncertain Approved Vesicles Renal cancer:1.69e-5 (favourable), Liver cancer:1.70e-4 (unfavourable) Expressed in all Tissue enhanced seminal vesicle: 138.7 prostate: 61.0 Expressed in all +SMIM1 Vel ENSG00000235169 Small integral membrane protein 1 (Vel blood group) 1 3772788-3775982 Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA069088 Uncertain Expressed in all Tissue enhanced bone marrow: 17.5;testis: 24.6 seminal vesicle: 7.5 Group enriched 6 HEL: 58.5;Hep G2: 21.1;K-562: 28.8 +HGH1 Brp16, C8orf30A, C8orf30B, FAM203A, FAM203B, FLJ40907, LOC51236 ENSG00000235173 HGH1 homolog 8 144137769-144140843 Predicted intracellular proteins Evidence at protein level HPA042470 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:3.72e-5 (unfavourable), Cervical cancer:3.12e-4 (unfavourable) Expressed in all Mixed adipose tissue,stomach: 2.6 Cell line enhanced PC-3: 43.5 +PPP1R3E FLJ00089 ENSG00000235194 Protein phosphatase 1 regulatory subunit 3E 14 23295643-23302848 Predicted intracellular proteins Evidence at protein level HPA061600 Approved Approved Microtubules
Mitotic spindle
Mitochondria Colorectal cancer:6.89e-5 (unfavourable), Lung cancer:3.10e-4 (favourable) Expressed in all Mixed thyroid gland: 14.5 Cell line enhanced U-266/70: 31.3 +KDM4E JMJD2E, KDM4DL, KDM5E ENSG00000235268 Lysine demethylase 4E 11 95025258-95027596 Predicted intracellular proteins Evidence at protein level HPA051740, HPA054225 Uncertain Not detected Not detected testis: 0.3 Not detected +RPEL1 ENSG00000235376 Ribulose-5-phosphate-3-epimerase like 1 10 103245887-103248016 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA036498, HPA036499 Approved Not detected Not detected all non-specific tissues: 0.0 Not detected +SPAAR LINC00961, SPAR ENSG00000235387 Small regulatory polypeptide of amino acid response 9 35909483-35937153 Predicted intracellular proteins Evidence at protein level Mixed Tissue enhanced adipose tissue: 8.1;testis: 10.9 placenta: 6.8 Group enriched 12 HUVEC TERT2: 28.2;TIME: 32.4 +TOPORS-AS1 C9orf133 ENSG00000235453 TOPORS antisense RNA 1 9 32551144-32567005 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Breast cancer:4.18e-5 (favourable), Pancreatic cancer:7.33e-5 (favourable), Renal cancer:3.46e-4 (favourable), Cervical cancer:6.11e-4 (favourable), Ovarian cancer:8.39e-4 (favourable) Expressed in all Expressed in all testis: 35.7 Mixed +NFAM1 CNAIP ENSG00000235568 NFAT activating protein with ITAM motif 1 22 42380410-42432395 Predicted membrane proteins Evidence at protein level HPA031812 Uncertain Endometrial cancer:6.16e-4 (favourable) Expressed in all Tissue enhanced appendix: 17.2;bone marrow: 20.2 spleen: 14.5 Cell line enhanced NB-4: 5.5;SCLC-21H: 6.8;THP-1: 25.4 +NKX1-1 HSPX153, SAX2 ENSG00000235608 NK1 homeobox 1 4 1402932-1406331 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA029367 Uncertain Not detected Not detected testis: 0.1 Not detected +RNF148 MGC35222 ENSG00000235631 Ring finger protein 148 7 122701664-122702967 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 228 testis: 73.5 lung: 0.3 Cell line enhanced Karpas-707: 1.9 +CXorf51B ENSG00000235699 Chromosome X open reading frame 51B X 146809784-146810409 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 1092 testis: 109.1 all non-specific tissues: 0.0 Cell line enhanced U-138 MG: 1.0 +ANKRD34C ENSG00000235711 Ankyrin repeat domain 34C 15 79293285-79298235 Predicted intracellular proteins Evidence at protein level HPA045329 Uncertain Approved Mitochondria Not detected Tissue enhanced cerebral cortex: 1.9 skin: 0.9 Cell line enriched 29 SCLC-21H: 10.0 +MFRP C1QTNF5, FLJ30570, NNO2, rd6 ENSG00000235718 Membrane frizzled-related protein 11 119338942-119346673 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Not detected Not detected parathyroid gland: 0.2 Not detected +KIAA0040 ENSG00000235750 KIAA0040 1 175156987-175192999 Predicted intracellular proteins Evidence at protein level HPA016895, HPA068812 Approved Approved Nucleoplasm Expressed in all Expressed in all placenta: 143.7 Cell line enhanced Daudi: 65.1;U-698: 80.2 +USP17L27 ENSG00000235780 Ubiquitin specific peptidase 17-like family member 27 4 9344148-9345740 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +B3GALT4 beta3Gal-T4, GalT4 ENSG00000235863 Beta-1,3-galactosyltransferase 4 6 33277132-33284832 Enzymes, Predicted secreted proteins Evidence at protein level HPA043001 Approved Expressed in all Mixed testis: 3.8 Cell line enhanced CAPAN-2: 1.8;SCLC-21H: 1.4;SK-BR-3: 1.5 +LCE6A C1orf44 ENSG00000235942 Late cornified envelope 6A 1 152842868-152843983 Predicted intracellular proteins Evidence at protein level HPA046376 Enhanced Tissue enriched Tissue enriched 11 skin: 303.8 breast: 26.8 Not detected +PNMA6A MGC15827, PNMA6C ENSG00000235961 Paraneoplastic Ma antigen family member 6A X 153072482-153075018 Predicted intracellular proteins Evidence at protein level HPA045007, HPA052115 Uncertain Uncertain Nucleoli
Mitochondria Renal cancer:1.93e-5 (favourable) Mixed Tissue enhanced cerebral cortex: 22.9 epididymis: 7.3 Cell line enhanced HHSteC: 6.4;U-2 OS: 15.5 +PATE3 HEL-127, PATE-DJ ENSG00000236027 Prostate and testis expressed 3 11 125788111-125791600 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 29 epididymis: 189.9 seminal vesicle: 6.4 Not detected +OR5H14 ENSG00000236032 Olfactory receptor family 5 subfamily H member 14 3 98149326-98150405 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected placenta,testis: 0.2 Not detected +ZBTB22 BING1, fru, fruitless, ZBTB22A, ZNF297, ZNF297A ENSG00000236104 Zinc finger and BTB domain containing 22 6 33314406-33317942 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043848 Approved Nucleoplasm Expressed in all Tissue enhanced parathyroid gland: 28.9 epididymis: 11.8 Mixed +USP17L4 ENSG00000236125 Ubiquitin specific peptidase 17-like family member 4 8 7337115-7338707 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +CT47A3 CT47.3 ENSG00000236126 Cancer/testis antigen family 47, member A3 X 120972746-120976068 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 20 testis: 2.0 all non-specific tissues: 0.0 Not detected +AC002429.5 ENSG00000236197 7 95035731-95214332 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 10 cerebral cortex: 2.7 esophagus: 0.2 Not detected +CLEC2L FLJ32986 ENSG00000236279 C-type lectin domain family 2 member L 7 139523856-139544984 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045050 Enhanced Mixed Group enriched 9 cerebral cortex: 21.0;parathyroid gland: 13.7 endometrium: 1.9 Cell line enhanced NTERA-2: 1.3;U-266/70: 2.4;U-266/84: 8.8 +ZBED5 Buster1 ENSG00000236287 Zinc finger BED-type containing 5 11 10812074-10858796 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048472, HPA050994 Uncertain Approved Nucleus
Nucleoli fibrillar center
Golgi apparatus Liver cancer:2.19e-5 (unfavourable), Urothelial cancer:3.87e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 90.6 Expressed in all +SLFN14 ENSG00000236320 Schlafen family member 14 17 35548125-35558098 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA022994, HPA023065 Uncertain Not detected Tissue enhanced bone marrow: 2.5 lymph node: 0.6 Cell line enriched 7 HEL: 19.4 +PPIAL4G ENSG00000236334 Peptidylprolyl isomerase A like 4G 1 148479824-148483679 Enzymes, Predicted intracellular proteins Evidence at protein level HPA058345 Uncertain Not detected Not detected skeletal muscle: 0.9 Not detected +GAGE12F ENSG00000236362 G antigen 12F X 49551278-49568218 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Cytosol Not detected Tissue enriched 23 testis: 300.5 stomach: 12.8 Group enriched 6 AN3-CA: 1052.1;K-562: 1042.6;T-47d: 255.7 +CT47A1 CT47.1 ENSG00000236371 Cancer/testis antigen family 47, member A1 X 120982476-120985788 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 15 testis: 1.4 all non-specific tissues: 0.0 Cell line enriched 8 U-266/70: 1.7 +LINC00854 TMEM106A-AS1 ENSG00000236383 Long intergenic non-protein coding RNA 854 17 43216941-43305397 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 11 testis: 45.4 spleen: 4.0 Mixed +SLC35G4 AMAC1L1, SLC35G4P ENSG00000236396 Solute carrier family 35 member G4 18 11609596-11610612 Predicted membrane proteins, Transporters No evidence Not detected Not detected testis: 0.1 Not detected +TAS2R39 ENSG00000236398 Taste 2 receptor member 39 7 143183419-143184435 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA053456, HPA060680 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +TSPY10 ENSG00000236424 Testis specific protein, Y-linked 10 Y 9527880-9530682 Predicted intracellular proteins Evidence at protein level HPA049384 Supported Tissue enriched Tissue enriched 17 testis: 3.1 adipose tissue: 0.1 Group enriched 208 U-266/70: 8.9;U-266/84: 43.7 +UBE2L5P UBE2L5 ENSG00000236444 Ubiquitin conjugating enzyme E2 L5, pseudogene 13 30422488-30428616 Predicted intracellular proteins Evidence at protein level HPA045609, HPA062415 Approved Uncertain Nucleus
Cytosol Mixed Tissue enriched 76 testis: 86.2 endometrium: 1.1 Not detected +CT47B1 CT47.13 ENSG00000236446 Cancer/testis antigen family 47, member B1 X 120872603-120875929 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 45 testis: 4.4 all non-specific tissues: 0.0 Not detected +RP11-98L5.5 ENSG00000236543 9 135604345-135618952 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 34 skin: 22.9 parathyroid gland,seminal vesicle: 0.6 Cell line enriched 21 BEWO: 7.4 +ZNF853 DKFZp434J1015 ENSG00000236609 Zinc finger protein 853 7 6615617-6624290 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067690 Approved Approved Nucleoli Renal cancer:2.30e-6 (favourable) Mixed Mixed cerebral cortex: 17.4 Cell line enhanced AN3-CA: 18.6;SH-SY5Y: 31.3;U-2 OS: 20.5 +IFNA4 IFN-alpha4a, MGC142200 ENSG00000236637 Interferon alpha 4 9 21186694-21187671 Predicted secreted proteins Evidence at protein level HPA047557 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +ARHGEF38 FLJ20184 ENSG00000236699 Rho guanine nucleotide exchange factor 38 4 105552620-105708093 Predicted intracellular proteins Evidence at protein level HPA036510, HPA045484 Uncertain Approved Nucleoplasm
Centrosome Tissue enhanced Tissue enhanced breast: 10.0;prostate: 9.3 epididymis: 6.8 Group enriched 8 RPTEC TERT1: 11.0;SK-BR-3: 6.0;T-47d: 7.9 +GAGE12B ENSG00000236737 G antigen 12B X 49529869-49529985 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced duodenum: 1.2 spleen: 0.4 Group enriched 20 PC-3: 2.6;U-2197: 1.4 +CTAGE9 ENSG00000236761 CTAGE family member 9 6 131708684-131711017 Predicted membrane proteins Evidence at protein level HPA000387, HPA000922 Uncertain Not detected Tissue enriched 41 testis: 7.6 duodenum,small intestine: 0.1 Not detected +RP11-96L14.7 ENSG00000236782 1 26169516-26171821 Predicted membrane proteins No evidence Not detected Not detected endometrium,ovary,testis: 0.4 Not detected +C3orf84 ENSG00000236980 Chromosome 3 open reading frame 84 3 49177632-49191858 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 77 testis: 7.6 all non-specific tissues: 0.0 Not detected +OR10G9 OR10G10P ENSG00000236981 Olfactory receptor family 10 subfamily G member 9 11 124023013-124023948 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +USP17L8 ENSG00000237038 Ubiquitin specific peptidase 17-like family member 8 8 7971661-7973253 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +TAAR9 TA3, TAR3, TRAR3 ENSG00000237110 Trace amine associated receptor 9 (gene/pseudogene) 6 132538290-132539336 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +C4orf51 ENSG00000237136 Chromosome 4 open reading frame 51 4 145680115-145771032 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 19 testis: 9.2 epididymis: 0.4 Not detected +B3GNT9 MGC4655 ENSG00000237172 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 16 67148105-67151214 Predicted secreted proteins Evidence at protein level HPA052743, HPA062734 Approved Supported Nucleoli fibrillar center
Golgi apparatus Expressed in all Tissue enhanced parathyroid gland: 49.9 thyroid gland: 28.2 Cell line enhanced SiHa: 49.7 +CDKN2AIPNL MGC13017 ENSG00000237190 CDKN2A interacting protein N-terminal like 5 134402087-134411898 Predicted intracellular proteins Evidence at protein level HPA043966 Approved Expressed in all Expressed in all thyroid gland: 35.4 Expressed in all +MBD3L5 ENSG00000237247 Methyl-CpG binding domain protein 3 like 5 19 7030578-7033011 Predicted intracellular proteins No evidence HPA051259 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +CKMT1B CKMT, CKMT1, UMTCK ENSG00000237289 Creatine kinase, mitochondrial 1B 15 43593054-43604901 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level HPA043491 Uncertain Endometrial cancer:2.55e-5 (unfavourable) Mixed Tissue enhanced colon: 78.0;rectum: 68.4 duodenum: 63.0 Cell line enhanced HaCaT: 120.7;SCLC-21H: 60.9;SK-BR-3: 124.3;T-47d: 91.0 +RNF223 ENSG00000237330 Ring finger protein 223 1 1070966-1074307 Predicted membrane proteins Evidence at transcript level Endometrial cancer:8.08e-5 (favourable), Pancreatic cancer:6.53e-4 (unfavourable) Mixed Tissue enhanced esophagus: 5.3;stomach: 3.6 skin: 2.0 Cell line enhanced A-431: 13.3;CAPAN-2: 9.8;HaCaT: 6.2;MCF7: 18.6;SK-BR-3: 12.0;T-47d: 9.8 +PATE4 FLJ41047, PATE-B ENSG00000237353 Prostate and testis expressed 4 11 125833316-125840069 Predicted secreted proteins Evidence at protein level HPA045632 Approved Not detected Tissue enriched 8 seminal vesicle: 148.4 epididymis: 18.3 Not detected +OR4A47 ENSG00000237388 Olfactory receptor family 4 subfamily A member 47 11 48488717-48489780 G-protein coupled receptors, Predicted membrane proteins No evidence HPA059763 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +PRSS56 ENSG00000237412 Protease, serine 56 2 232520463-232525716 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Tissue enhanced Tissue enhanced skeletal muscle: 3.4 testis: 0.8 Not detected +ZNF737 ZNF102 ENSG00000237440 Zinc finger protein 737 19 20535825-20565809 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Mixed thyroid gland: 66.9 Cell line enhanced MOLT-4: 22.1;RT4: 22.5 +RGL2 HKE1.5, KE1.5, RAB2L ENSG00000237441 Ral guanine nucleotide dissociation stimulator like 2 6 33291654-33299324 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA047039, HPA053444 Approved Approved Nucleoplasm Pancreatic cancer:6.16e-4 (favourable) Expressed in all Mixed spleen: 1.5 Mixed +BHMG1 HMGDC ENSG00000237452 Basic helix-loop-helix and HMG-box containing 1 19 45733251-45764534 Predicted intracellular proteins Evidence at transcript level HPA049521 Uncertain Tissue enriched Tissue enriched 77 testis: 7.6 all non-specific tissues: 0.0 Cell line enhanced Daudi: 1.0;K-562: 3.0 +LINC00959 ENSG00000237489 Long intergenic non-protein coding RNA 959 10 130063900-130110817 Predicted intracellular proteins Evidence at transcript level Mixed Mixed thyroid gland: 10.9 Cell line enhanced NB-4: 8.8 +SHISA9 ENSG00000237515 Shisa family member 9 16 12901620-13240413 Predicted membrane proteins Evidence at transcript level Renal cancer:1.53e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 22.8 prostate: 7.2 Cell line enhanced EFO-21: 46.5;LHCN-M2: 33.9 +OR7E24 HSHT2, OR19-8, OR7E24P, OR7E24Q ENSG00000237521 Olfactory receptor family 7 subfamily E member 24 19 9250930-9252479 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enriched 25 testis: 2.5 all non-specific tissues: 0.0 Not detected +AC114783.1 ENSG00000237524 2 126898882-126902097 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 183 testis: 57.8 kidney: 0.3 Not detected +HLA-DQA2 HLA-DXA ENSG00000237541 Major histocompatibility complex, class II, DQ alpha 2 6 32741342-32747215 Predicted membrane proteins Evidence at protein level Expressed in all Not detected tonsil: 0.3 Not detected +KIFC1 HSET, KNSL2 ENSG00000237649 Kinesin family member C1 6 33391536-33409924 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055997, HPA062674 Supported Approved Centrosome Renal cancer:0.00e+0 (unfavourable), Liver cancer:7.07e-8 (unfavourable), Pancreatic cancer:4.21e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 3.2 bone marrow: 2.8 Mixed +C2orf74 LOC339804 ENSG00000237651 Chromosome 2 open reading frame 74 2 61145068-61164829 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA026826 Approved Approved Centrosome Mixed Expressed in all testis: 80.5 Mixed +GAGE12C ENSG00000237671 G antigen 12C X 49532211-49539538 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Not detected Tissue enriched 461 testis: 46.0 all non-specific tissues: 0.0 Group enriched 10 U-2 OS: 9.9;U-266/84: 25.6 +IRGM IFI1, IRGM1, LRG-47, LRG47 ENSG00000237693 Immunity related GTPase M 5 150846523-150900736 Disease related genes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced testis: 1.6 appendix,spleen: 0.5 Cell line enhanced NB-4: 1.6;U-937: 2.4 +PRAMEF33 PRAMEF33P ENSG00000237700 PRAME family member 33 1 13303539-13308907 Predicted intracellular proteins No evidence Tissue enriched Not detected all non-specific tissues: 0.0 Not detected +AMY1A AMY1 ENSG00000237763 Amylase, alpha 1A (salivary) 1 103655290-103664554 Enzymes, Predicted secreted proteins Evidence at protein level CAB004310, HPA045394, HPA045399, HPA046980 Supported Not detected Tissue enriched 79 salivary gland: 8875.9 cervix, uterine: 111.7 Not detected +FAM200B C4orf53 ENSG00000237765 Family with sequence similarity 200 member B 4 15681662-15705565 Predicted intracellular proteins Evidence at protein level HPA017855 Uncertain Urothelial cancer:3.35e-5 (favourable), Renal cancer:3.87e-4 (favourable), Pancreatic cancer:4.39e-4 (favourable), Lung cancer:9.89e-4 (favourable) Expressed in all Mixed thyroid gland: 15.0 Mixed +FAM231A ENSG00000237847 Family with sequence similarity 231 member A 1 16673003-16673512 Predicted intracellular proteins No evidence HPA043267, HPA043292 Uncertain Not detected Not detected testis: 0.1 Not detected +CT47A5 CT47.5 ENSG00000237957 Cancer/testis antigen family 47, member A5 X 120963026-120966348 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 20 testis: 2.0 all non-specific tissues: 0.0 Not detected +LRRC37A2 FLJ45049 ENSG00000238083 Leucine rich repeat containing 37 member A2 17 46511511-46555650 Predicted membrane proteins Evidence at protein level HPA042121, HPA042701, HPA043056, HPA045090, HPA049080 Supported Approved Vesicles Mixed Tissue enriched 25 testis: 13.0 breast,lung: 0.5 Not detected +MPC1L ENSG00000238205 Mitochondrial pyruvate carrier 1-like X 40623566-40624136 Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 67 testis: 12.0 epididymis,lung,lymph node: 0.1 Not detected +RP13-210D15.4 ENSG00000238210 X 135252061-135253583 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 16 testis: 11.8 skin: 0.7 Not detected +C9orf69 bA83N9.1 ENSG00000238227 Chromosome 9 open reading frame 69 9 136114581-136118863 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066070 Supported Supported Nucleoplasm Endometrial cancer:1.09e-4 (favourable) Expressed in all Expressed in all skin: 23.7 Expressed in all +OR2W3 OR2W3P, OR2W8P, OST718 ENSG00000238243 Olfactory receptor family 2 subfamily W member 3 1 247895587-247896531 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA045594 Uncertain Tissue enhanced Tissue enhanced bone marrow: 7.8;thyroid gland: 10.5 cerebral cortex: 2.9 Cell line enhanced HEL: 12.1;PC-3: 12.2;U-2 OS: 8.8;WM-115: 9.3 +PAGE2B CT16.5 ENSG00000238269 PAGE family member 2B X 55075063-55078909 Predicted intracellular proteins Evidence at protein level HPA052619 Supported Endometrial cancer:3.02e-4 (unfavourable) Mixed Tissue enriched 29 testis: 84.8 bone marrow: 2.8 Group enriched 6 U-266/70: 1167.1;U-266/84: 1756.5 +TXNDC5 EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15 ENSG00000239264 Thioredoxin domain containing 5 6 7881517-7910814 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA034677, HPA034678 Enhanced Approved Endoplasmic reticulum Renal cancer:1.16e-4 (unfavourable) Expressed in all Expressed in all urinary bladder: 312.7 Expressed in all +GATSL3 ENSG00000239282 GATS protein like 3 22 30285117-30289627 Predicted intracellular proteins Evidence at protein level Mixed Mixed esophagus: 22.8 Mixed +RNF103 hkf-1, KF1, ZFP103 ENSG00000239305 Ring finger protein 103 2 86603393-86623866 Enzymes, Predicted membrane proteins Evidence at protein level HPA057922 Approved Urothelial cancer:6.77e-5 (favourable) Expressed in all Expressed in all epididymis: 55.3 Expressed in all +RBM14 COAA, DKFZp779J0927, SIP, SYTIP1 ENSG00000239306 RNA binding motif protein 14 11 66616582-66627347 Predicted intracellular proteins Evidence at protein level HPA006628 Supported Supported Nuclear speckles Liver cancer:2.02e-7 (unfavourable), Pancreatic cancer:1.04e-4 (favourable) Expressed in all Expressed in all testis: 50.0 Expressed in all +ALKBH6 MGC15677 ENSG00000239382 AlkB homolog 6 19 36009120-36014239 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA073835, HPA074340 Supported Nucleoplasm
Focal adhesion sites Expressed in all Mixed cerebral cortex: 7.5 Expressed in all +ASB14 DKFZp313L0121 ENSG00000239388 Ankyrin repeat and SOCS box containing 14 3 57268347-57292682 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced skeletal muscle: 9.9 heart muscle: 2.4 Not detected +PCDHA13 CNR5, CNRN5, CNRS5, CRNR5, PCDH-ALPHA13 ENSG00000239389 Protocadherin alpha 13 5 140882208-141012344 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 6 parathyroid gland: 6.8 cerebral cortex,testis: 1.0 Cell line enhanced AN3-CA: 1.0;PC-3: 3.5;WM-115: 1.1 +KLHL41 KBTBD10, Krp1, SARCOSIN ENSG00000239474 Kelch like family member 41 2 169509702-169526262 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021165, HPA021753, HPA021760 Enhanced Supported Nucleus
Plasma membrane
Cytosol Group enriched Tissue enriched 22 skeletal muscle: 1750.6 esophagus: 79.6 Group enriched 8 HSkMC: 15.5;LHCN-M2: 29.3;RH-30: 53.9 +GATS DKFZp686B07267, STAG3OS ENSG00000239521 GATS, stromal antigen 3 opposite strand 7 100200653-100272218 Predicted intracellular proteins Evidence at transcript level HPA043176 Uncertain Cervical cancer:7.56e-7 (favourable) Expressed in all Tissue enhanced cerebral cortex: 3.3;skeletal muscle: 2.2 bone marrow: 0.7 Cell line enhanced A549: 1.4 +OR1J4 HSHTPCRX01, HTPCRX01 ENSG00000239590 Olfactory receptor family 1 subfamily J member 4 9 122519141-122520082 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected epididymis: 0.2 Not detected +C2orf61 FLJ40172 ENSG00000239605 Chromosome 2 open reading frame 61 2 47045538-47155287 Predicted intracellular proteins Evidence at transcript level HPA047366, HPA052691 Approved Approved Nucleoplasm
Cytosol Not detected Tissue enhanced testis: 1.3 gallbladder: 0.3 Cell line enhanced Karpas-707: 1.4 +MEIKIN ENSG00000239642 Meiotic kinetochore factor 5 131806993-131945698 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 19 testis: 13.4 parathyroid gland: 0.7 Cell line enriched 8 U-2 OS: 1.6 +NME1 NDPKA, NM23, NM23-H1 ENSG00000239672 NME/NM23 nucleoside diphosphate kinase 1 17 51153536-51162428 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008467, CAB040571, HPA041113 Supported Enhanced Nucleoplasm
Cytosol Renal cancer:2.07e-9 (unfavourable), Liver cancer:2.60e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 89.3 Expressed in all +TNFSF12 APO3L, DR3LG, TWEAK ENSG00000239697 Tumor necrosis factor superfamily member 12 17 7548891-7557890 Predicted secreted proteins Evidence at protein level HPA052967 Uncertain Endometrial cancer:5.70e-5 (favourable) Expressed in all Mixed seminal vesicle: 27.2 Mixed +CDRT4 FLJ36674 ENSG00000239704 CMT1A duplicated region transcript 4 17 15436015-15503608 Predicted intracellular proteins Evidence at transcript level HPA021590 Uncertain Approved Mitochondria Not detected Tissue enhanced epididymis: 30.3 skin: 26.3 Cell line enhanced Hep G2: 7.6 +APOBEC3G bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019 ENSG00000239713 Apolipoprotein B mRNA editing enzyme catalytic subunit 3G 22 39077005-39087743 Predicted intracellular proteins Evidence at protein level HPA001812, HPA073637 Approved Uncertain Nucleoplasm
Cytosol Renal cancer:8.66e-13 (unfavourable), Endometrial cancer:6.03e-5 (favourable), Cervical cancer:4.70e-4 (favourable), Breast cancer:4.78e-4 (favourable), Urothelial cancer:6.30e-4 (favourable) Expressed in all Mixed lymph node: 46.0 Cell line enhanced HDLM-2: 29.7;Karpas-707: 30.4 +TLR9 CD289 ENSG00000239732 Toll like receptor 9 3 52221080-52226163 CD markers, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced lymph node: 3.0 spleen: 2.0 Group enriched 10 Daudi: 23.9;RPMI-8226: 14.8;U-698: 8.8 +WBP1 WBP-1 ENSG00000239779 WW domain binding protein 1 2 74458329-74460891 Predicted membrane proteins Evidence at protein level HPA057067 Approved Approved Cytosol Colorectal cancer:1.04e-4 (unfavourable), Urothelial cancer:6.36e-4 (favourable), Pancreatic cancer:6.83e-4 (favourable) Expressed in all Expressed in all thyroid gland: 91.5 Expressed in all +MRPS17 HSPC011, MRP-S17, RPMS17 ENSG00000239789 Mitochondrial ribosomal protein S17 7 55951819-55956501 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047159 Approved Expressed in all Expressed in all fallopian tube: 16.0 Expressed in all +PRAMEF11 ENSG00000239810 PRAME family member 11 1 12824605-12831410 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.2 Not detected +DEFA3 DEF3, HNP-3 ENSG00000239839 Defensin alpha 3 8 7015869-7018301 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA052517 Supported Not detected Tissue enriched 246 bone marrow: 23273.5 spleen: 94.7 Not detected +GET4 C7orf20, CEE, CGI-20, H_NH1244M04.5, TRC35 ENSG00000239857 Golgi to ER traffic protein 4 7 876552-896436 Predicted intracellular proteins Evidence at protein level HPA019765 Uncertain Supported Nucleoplasm
Nucleoli
Cytosol Expressed in all Expressed in all testis: 49.7 Expressed in all +KRTAP9-2 KAP9.2 ENSG00000239886 Keratin associated protein 9-2 17 41226648-41227652 Predicted intracellular proteins Evidence at protein level Not detected Not detected testis: 0.1 Not detected +C1orf226 FLJ13137 ENSG00000239887 Chromosome 1 open reading frame 226 1 162366908-162386818 Predicted intracellular proteins Evidence at protein level HPA052251 Approved Approved Nucleoplasm Renal cancer:4.44e-5 (favourable), Urothelial cancer:1.13e-4 (favourable), Breast cancer:2.60e-4 (favourable) Expressed in all Mixed adrenal gland: 12.7 Cell line enhanced HEL: 20.8 +ADSL ENSG00000239900 Adenylosuccinate lyase 22 40346500-40390463 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000525, CAB019285 Enhanced Enhanced Cytosol Liver cancer:5.81e-8 (unfavourable), Colorectal cancer:2.38e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 127.3 Expressed in all +LILRA4 CD85g, ILT7 ENSG00000239961 Leukocyte immunoglobulin like receptor A4 19 54333185-54339150 CD markers, Predicted membrane proteins Evidence at protein level HPA049418 Approved Mixed Tissue enhanced spleen: 2.1;tonsil: 2.5 lymph node: 0.9 Not detected +LILRA2 CD85h, ILT1, LIR-7, LIR7 ENSG00000239998 Leukocyte immunoglobulin like receptor A2 19 54572920-54590287 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Mixed Tissue enhanced bone marrow: 9.9;spleen: 7.0 appendix: 4.0 Cell line enhanced REH: 1.8;THP-1: 2.7;U-937: 7.1 +TEX35 C1orf49, DKFZP564J047, TSC24 ENSG00000240021 Testis expressed 35 1 178513077-178548602 Predicted intracellular proteins Evidence at protein level HPA039190 Approved Not detected Tissue enriched 34 testis: 174.3 skin: 5.1 Mixed +AMY2B AMY2 ENSG00000240038 Amylase, alpha 2B (pancreatic) 1 103553815-103579534 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA045394, HPA045399, HPA046980 Supported Tissue enriched Tissue enriched 66 pancreas: 6585.9 salivary gland: 99.6 Cell line enhanced EFO-21: 9.6 +RP11-451G4.2 ENSG00000240045 3 155290229-155293775 Predicted membrane proteins Evidence at transcript level Mixed Tissue enriched 25 skeletal muscle: 400.8 prostate: 15.8 Not detected +LY6G5B C6orf19, G5b ENSG00000240053 Lymphocyte antigen 6 family member G5B 6 31670167-31673776 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048307 Approved Mixed Expressed in all skin: 27.1 Expressed in all +PSMB9 beta1i, LMP2, PSMB6i, RING12 ENSG00000240065 Proteasome subunit beta 9 6 32844136-32859585 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015180, HPA042818, HPA053280 Enhanced Supported Cytosol Renal cancer:1.33e-4 (unfavourable) Expressed in all Mixed spleen: 39.1 Cell line enhanced Daudi: 46.2;REH: 43.8 +PCDHGC3 PC-43, PC43, PCDH-GAMMA-C3, PCDH2 ENSG00000240184 Protocadherin gamma subfamily C, 3 5 141475947-141512979 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008755, HPA010580, HPA077289 Approved Approved Nucleus
Vesicles
Plasma membrane
Cytosol Urothelial cancer:6.00e-4 (unfavourable), Ovarian cancer:6.19e-4 (unfavourable), Renal cancer:8.18e-4 (unfavourable) Group enriched Tissue enhanced cerebral cortex: 376.0 cervix, uterine: 93.8 Cell line enhanced U-138 MG: 264.5;WM-115: 404.1 +SMKR1 ENSG00000240204 Small lysine rich protein 1 7 129502479-129512932 Predicted intracellular proteins Evidence at transcript level HPA078358 Approved Nucleoli Mixed Tissue enriched 13 testis: 119.8 fallopian tube: 9.4 Cell line enhanced SCLC-21H: 34.4 +UGT1A5 UGT1E ENSG00000240224 UDP glucuronosyltransferase family 1 member A5 2 233712992-233773299 Enzymes, Predicted membrane proteins Evidence at transcript level Not detected Group enriched 7 duodenum: 7.5;gallbladder: 3.9;small intestine: 6.8 liver: 0.9 Not detected +COX19 MGC104475 ENSG00000240230 COX19, cytochrome c oxidase assembly factor 7 898778-975599 Predicted intracellular proteins Evidence at protein level HPA021226 Approved Enhanced Cytosol Expressed in all Expressed in all fallopian tube: 10.0 Mixed +DEFA1B ENSG00000240247 Defensin alpha 1B 8 6996766-6999195 Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA052517 Supported Not detected Tissue enriched 463 bone marrow: 46364.0 spleen: 100.2 Not detected +ACAD11 FLJ12592 ENSG00000240303 Acyl-CoA dehydrogenase family member 11 3 132558138-132660723 Predicted intracellular proteins Evidence at protein level HPA048317 Enhanced Tissue enhanced Expressed in all kidney: 35.4 Mixed +PPIL3 CyPJ ENSG00000240344 Peptidylprolyl isomerase like 3 2 200870907-200889303 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040765, HPA062187 Approved Supported Nucleus Ovarian cancer:1.19e-4 (favourable), Renal cancer:5.16e-4 (unfavourable) Expressed in all Expressed in all ovary: 45.3 Expressed in all +LCE1F LEP6 ENSG00000240386 Late cornified envelope 1F 1 152776372-152776728 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enriched 21 skin: 246.9 breast: 11.9 Cell line enhanced BJ hTERT+: 5.4;hTEC/SVTERT24-B: 1.1;hTERT-HME1: 2.3 +KIR3DL2 CD158K, cl-5, nkat4, nkat4a, nkat4b ENSG00000240403 Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 19 54850443-54867207 CD markers, Predicted membrane proteins Evidence at transcript level Not detected Not detected bone marrow: 0.1 Not detected +KRTAP13-3 KAP13.3 ENSG00000240432 Keratin associated protein 13-3 21 30425265-30425968 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +TNFRSF13B CD267, IGAD2, TACI ENSG00000240505 TNF receptor superfamily member 13B 17 16929816-16972118 CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030453 Uncertain Not detected Tissue enhanced lymph node: 20.3;skeletal muscle: 22.1;spleen: 27.2;tonsil: 21.0 appendix: 12.1 Group enriched 8 Karpas-707: 120.9;RPMI-8226: 76.1;U-266/70: 56.5 +KRTAP9-1 KAP9.1, KRTAP9L3 ENSG00000240542 Keratin associated protein 9-1 17 41189887-41190639 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 42 HDLM-2: 4.2 +L1TD1 ECAT11, FLJ10884 ENSG00000240563 LINE1 type transposase domain containing 1 1 62194831-62212328 Predicted intracellular proteins Evidence at protein level Tissue enriched Tissue enhanced placenta: 16.6;testis: 11.0 appendix: 6.1 Cell line enriched 26 NTERA-2: 254.5 +AQP1 CHIP28, CO ENSG00000240583 Aquaporin 1 (Colton blood group) 7 30911694-30925516 Blood group antigen proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB001707, HPA019206 Enhanced Supported Plasma membrane Renal cancer:1.32e-8 (favourable), Head and neck cancer:6.52e-4 (favourable) Expressed in all Expressed in all kidney: 791.4 Cell line enhanced EFO-21: 37.4;SH-SY5Y: 15.9;U-2 OS: 19.3;WM-115: 72.2 +C1QTNF9 AQL1, C1QTNF9A, CTRP9, MGC48915 ENSG00000240654 C1q and tumor necrosis factor related protein 9 13 24307166-24322535 Predicted secreted proteins Evidence at protein level HPA056632 Uncertain Not detected Tissue enhanced skeletal muscle: 2.9 adipose tissue: 2.1 Not detected +ISY1 fSAP33, KIAA1160 ENSG00000240682 ISY1 splicing factor homolog 3 129127415-129161293 Predicted intracellular proteins Evidence at protein level HPA006312, HPA016995 Supported Enhanced Nuclear speckles Cervical cancer:2.46e-5 (favourable), Liver cancer:7.25e-4 (unfavourable) Expressed in all Expressed in all lymph node: 36.5 Expressed in all +PNMA2 MA2, RGAG2 ENSG00000240694 Paraneoplastic Ma antigen 2 8 26504686-26514092 Predicted intracellular proteins Evidence at protein level HPA001936 Enhanced Lung cancer:1.81e-4 (favourable), Stomach cancer:6.23e-4 (unfavourable) Tissue enhanced Tissue enriched 12 cerebral cortex: 163.4 adrenal gland: 13.5 Cell line enhanced AF22: 59.2;HAP1: 38.7;SH-SY5Y: 45.6 +LRRD1 IMAGE:4798971 ENSG00000240720 Leucine rich repeats and death domain containing 1 7 92112159-92179531 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 53 testis: 30.0 epididymis,skin: 0.5 Not detected +KRBOX1 ENSG00000240747 KRAB box domain containing 1 3 42809483-42942792 Predicted intracellular proteins Evidence at transcript level HPA046901 Approved Nucleoplasm
Golgi apparatus Mixed Tissue enriched 31 testis: 289.2 epididymis: 9.3 Cell line enhanced CAPAN-2: 42.0;EFO-21: 21.7;hTEC/SVTERT24-B: 33.3;U-2197: 61.0 +PCDHGC5 PCDH-GAMMA-C5 ENSG00000240764 Protocadherin gamma subfamily C, 5 5 141489121-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580, HPA051540 Uncertain Approved Nucleus
Nucleoplasm
Vesicles
Plasma membrane
Cytosol Group enriched Tissue enriched 43 cerebral cortex: 50.6 smooth muscle: 1.1 Cell line enhanced U-138 MG: 14.5;U-251 MG: 5.4;U-87 MG: 8.8 +ARHGEF25 GEFT, p63RhoGEF ENSG00000240771 Rho guanine nucleotide exchange factor 25 12 57610180-57619379 Predicted intracellular proteins Evidence at protein level HPA052016 Uncertain Approved Vesicles Renal cancer:4.20e-7 (unfavourable) Expressed in all Mixed endometrium: 112.2 Cell line enhanced RH-30: 125.8;SH-SY5Y: 62.5 +TMEM189 Kua ENSG00000240849 Transmembrane protein 189 20 50118254-50153734 Predicted membrane proteins Evidence at protein level HPA059549 Approved Supported Endoplasmic reticulum Renal cancer:5.79e-11 (unfavourable), Endometrial cancer:7.51e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 31.3 Expressed in all +RDH14 PAN2, SDR7C4 ENSG00000240857 Retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 2 18554723-18560680 Predicted intracellular proteins Evidence at protein level HPA056686 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 31.6 Expressed in all +KRTAP4-7 KAP4.7 ENSG00000240871 Keratin associated protein 4-7 17 41084150-41085141 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +PLCXD2 FLJ31579 ENSG00000240891 Phosphatidylinositol specific phospholipase C X domain containing 2 3 111674676-111846447 Predicted intracellular proteins Evidence at protein level HPA055947 Uncertain Approved Nucleoplasm Renal cancer:1.23e-7 (favourable), Urothelial cancer:2.99e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 6.4 lymph node: 3.3 Mixed +MIF GIF, GLIF ENSG00000240972 Macrophage migration inhibitory factor (glycosylation-inhibiting factor) 22 23894004-23895227 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003868, CAB005284 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all prostate: 41.3 Expressed in all +GVQW1 bA205M20.5, TIGD1L2 ENSG00000241043 GVQW motif containing 1 9 32566789-32568621 Predicted secreted proteins Evidence at transcript level HPA074576 Approved Mitochondria Mixed Mixed parathyroid gland: 2.2 Mixed +NSUN6 ARL5B-AS1, FLJ23743, NOPD1 ENSG00000241058 NOP2/Sun RNA methyltransferase family member 6 10 18545561-18659285 Predicted intracellular proteins Evidence at protein level HPA045902 Approved Approved Golgi apparatus Renal cancer:5.55e-5 (unfavourable), Lung cancer:8.42e-4 (favourable) Expressed in all Expressed in all liver: 30.7 Expressed in all +HLA-DOB ENSG00000241106 Major histocompatibility complex, class II, DO beta 6 32812763-32817048 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013846 Enhanced Renal cancer:3.15e-5 (unfavourable), Ovarian cancer:4.17e-5 (favourable), Breast cancer:4.29e-4 (favourable) Expressed in all Group enriched 5 lymph node: 19.6;spleen: 18.6;tonsil: 30.7;urinary bladder: 8.3 colon: 3.5 Cell line enhanced Daudi: 37.8;U-698: 12.8;U-937: 6.1 +UGT1A9 HLUGP4, LUGP4, UGT1AI ENSG00000241119 UDP glucuronosyltransferase family 1 member A9 2 233671853-233773300 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Renal cancer:5.04e-5 (unfavourable) Group enriched Group enriched 592 kidney: 465.5;liver: 93.3 cerebral cortex,colon: 0.4 Cell line enhanced A549: 1.2 +KRTAP10-5 KAP10.5, KAP18.5, KRTAP18-5 ENSG00000241123 Keratin associated protein 10-5 21 44579455-44580604 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +YAE1D1 C7orf36, GK003 ENSG00000241127 Yae1 domain containing 1 7 39566376-39610320 Predicted intracellular proteins Evidence at protein level HPA019226, HPA031249 Uncertain Approved Cytosol Liver cancer:1.64e-4 (unfavourable) Expressed in all Expressed in all testis: 34.5 Expressed in all +OR14A2 OR5AX1, OR5AX1P ENSG00000241128 Olfactory receptor family 14 subfamily A member 2 1 247723099-247724043 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA052685 Uncertain Not detected Tissue enriched 51 testis: 5.0 all non-specific tissues: 0.0 Not detected +RP11-561N12.2 ENSG00000241149 7 63998874-64016130 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 38 testis: 3.7 all non-specific tissues: 0.0 Not detected +TDGF1 CR, CRIPTO, Cripto-1 ENSG00000241186 Teratocarcinoma-derived growth factor 1 3 46574534-46582463 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enhanced spleen: 24.8 kidney: 8.1 Group enriched 30 HEL: 19.6;NTERA-2: 95.4 +FLJ22763 ENSG00000241224 Uncharacterized LOC401081 3 109118252-109150514 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enhanced duodenum: 97.6;small intestine: 94.5 kidney: 19.5 Cell line enhanced CACO-2: 1.0 +KRTAP5-8 KRTAP5-2, KRTAP5.8, UHSKerB ENSG00000241233 Keratin associated protein 5-8 11 71538025-71539207 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enhanced testis: 1.1 epididymis,kidney: 0.8 Not detected +KRTAP4-16 KAP4A, KRTAP4-16P, KRTAP4P1 ENSG00000241241 Keratin associated protein 4-16 17 41101502-41102209 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +CRCP CGRP-RCP, RCP, RCP9 ENSG00000241258 CGRP receptor component 7 66114604-66154568 Predicted intracellular proteins Evidence at protein level HPA007216 Approved Approved Nuclear bodies Expressed in all Expressed in all parathyroid gland: 32.1 Expressed in all +CDRT1 FBXW10B, FBXW10P1, HREP, SM25H2 ENSG00000241322 CMT1A duplicated region transcript 1 17 15565483-15619512 Predicted intracellular proteins Evidence at transcript level HPA013332, HPA047457 Approved Nucleus
Nucleoli Not detected Tissue enhanced testis: 20.3 esophagus: 5.1 Cell line enhanced CAPAN-2: 20.4;HaCaT: 37.7 +RPL36A L36A, RPL44 ENSG00000241343 Ribosomal protein L36a X 101390824-101396154 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA063979, HPA077586 Uncertain Supported Endoplasmic reticulum
Plasma membrane
Cytosol Renal cancer:8.81e-11 (unfavourable) Expressed in all Expressed in all ovary: 3453.0 Expressed in all +PDXP CIN, dJ37E16.5, FLJ32703 ENSG00000241360 Pyridoxal phosphatase 22 37658727-37666934 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000531 Approved Mixed Tissue enhanced cerebral cortex: 135.9 testis: 30.5 Mixed +RPP21 C6orf135, Em:AB014085.3, FLJ22638 ENSG00000241370 Ribonuclease P/MRP subunit p21 6 30345131-30346884 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:1.04e-5 (unfavourable), Urothelial cancer:6.78e-5 (favourable) Expressed in all Mixed skin: 16.1 Cell line enhanced HEK 293: 51.3;SCLC-21H: 53.7 +CD302 BIMLEC, CLEC13A, DCL-1, KIAA0022 ENSG00000241399 CD302 molecule 2 159768630-159798255 CD markers, Predicted membrane proteins Evidence at protein level Mixed Expressed in all liver: 104.7 Cell line enhanced ASC diff: 178.2 +EGFL8 C6orf8, NG3 ENSG00000241404 EGF like domain multiple 8 6 32164583-32168281 Predicted secreted proteins Evidence at protein level HPA061173 Uncertain Approved Nuclear speckles
Vesicles Mixed Mixed skin: 2.7 Mixed +ATP5J2 ATP5JL, F1Fo-ATPase ENSG00000241468 ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2 7 99448475-99466331 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067267, HPA070412 Approved Supported Mitochondria Head and neck cancer:2.58e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 463.1 Expressed in all +SSX2 CT5.2a, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX ENSG00000241476 SSX family member 2 X 52696896-52707189 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045683, CAB046020 Enhanced Approved Nucleus
Nucleoli Not detected Tissue enriched 113 testis: 46.1 thyroid gland: 0.4 Not detected +ARHGAP8 BPGAP1, FLJ20185 ENSG00000241484 Rho GTPase activating protein 8 22 44752558-44862788 Predicted intracellular proteins Evidence at protein level HPA069694 Approved Approved Nucleus Mixed Mixed epididymis: 14.2 Cell line enhanced BEWO: 45.6;CACO-2: 25.6;HEK 293: 38.0;MCF7: 33.7;SK-BR-3: 30.9 +AF011889.5 ENSG00000241489 X 149482543-149533935 Predicted intracellular proteins Evidence at transcript level Not detected Expressed in all epididymis: 65.7 Mixed +ARPC4 ARC20, p20-Arc ENSG00000241553 Actin related protein 2/3 complex subunit 4 3 9792495-9807726 Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:1.29e-4 (unfavourable), Urothelial cancer:2.34e-4 (favourable) Expressed in all Expressed in all lymph node: 164.7 Expressed in all +CORT MGC32686 ENSG00000241563 Cortistatin 1 10449719-10451902 Predicted secreted proteins Evidence at transcript level Mixed Tissue enriched 24 cerebral cortex: 24.8 placenta: 1.0 Mixed +KRTAP9-4 KAP9.4 ENSG00000241595 Keratin associated protein 9-4 17 41249687-41250653 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP5-4 KRTAP5.4 ENSG00000241598 Keratin associated protein 5-4 11 1620958-1622138 Predicted intracellular proteins No evidence Not detected Not detected skeletal muscle: 0.1 Not detected +UGT1A1 GNT1, UGT1, UGT1A ENSG00000241635 UDP glucuronosyltransferase family 1 member A1 2 233760248-233773299 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Tissue enriched Group enriched 33 duodenum: 199.5;liver: 155.8;small intestine: 81.9 kidney: 4.3 Cell line enhanced HaCaT: 12.7;PC-3: 6.0;RT4: 27.4 +INMT ENSG00000241644 Indolethylamine N-methyltransferase 7 30697985-30757602 Enzymes, Predicted intracellular proteins Evidence at protein level HPA061343 Approved Golgi apparatus
Vesicles Liver cancer:5.72e-4 (favourable) Tissue enhanced Tissue enhanced lung: 144.8 seminal vesicle: 66.2 Group enriched 6 CACO-2: 13.8;HHSteC: 5.7 +ARPC1A Arc40, SOP2Hs, SOP2L ENSG00000241685 Actin related protein 2/3 complex subunit 1A 7 99325910-99366262 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004334 Approved Approved Cell Junctions
Cytosol Liver cancer:4.70e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 130.9 Expressed in all +RP5-860F19.8 ENSG00000241690 20 2814968-2818066 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 43 testis: 10.6 epididymis,placenta: 0.2 Cell line enriched 5 HDLM-2: 9.0 +TMEFF1 C9orf2, CT120.1, H7365 ENSG00000241697 Transmembrane protein with EGF like and two follistatin like domains 1 9 100473113-100577636 Predicted membrane proteins Evidence at protein level HPA051501 Uncertain Tissue enhanced Tissue enriched 5 cerebral cortex: 10.7 testis: 2.0 Cell line enhanced NTERA-2: 28.1;REH: 17.9;SCLC-21H: 28.0;SH-SY5Y: 16.8 +SPRR2A ENSG00000241794 Small proline rich protein 2A 1 153056113-153057537 Predicted intracellular proteins Evidence at protein level Urothelial cancer:1.37e-5 (unfavourable) Tissue enhanced Tissue enriched 8 esophagus: 5298.0 tonsil: 643.7 Group enriched 8 HaCaT: 5.3;hTCEpi: 5.2;hTERT-HME1: 7.3;Karpas-707: 8.4;U-266/70: 1.8 +ATP5O ATPO, OSCP ENSG00000241837 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 21 33903453-33915980 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016209, HPA041394 Enhanced Supported Mitochondria Renal cancer:9.34e-4 (favourable) Expressed in all Expressed in all heart muscle: 533.0 Expressed in all +PLEKHO2 DKFZp761K2312, PLEKHQ1, PP1628, pp9099 ENSG00000241839 Pleckstrin homology domain containing O2 15 64841883-64868007 Predicted intracellular proteins Evidence at protein level HPA040055 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all spleen: 119.5 Mixed +C8orf58 FLJ34715 ENSG00000241852 Chromosome 8 open reading frame 58 8 22599601-22604150 Predicted intracellular proteins Evidence at transcript level HPA024667, HPA028286 Uncertain Approved Nuclear bodies Renal cancer:3.58e-6 (unfavourable) Expressed in all Mixed placenta: 23.9 Mixed +PISD dJ858B16.2, PSDC ENSG00000241878 Phosphatidylserine decarboxylase 22 31618491-31662432 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031090, HPA031091 Approved Approved Golgi apparatus
Cytosol Urothelial cancer:5.27e-5 (favourable) Expressed in all Expressed in all adipose tissue: 35.9 Expressed in all +HOGA1 C10orf65, DHDPS2, DHDPSL, FLJ37472, NPL2 ENSG00000241935 4-hydroxy-2-oxoglutarate aldolase 1 10 97584323-97612802 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039466 Approved Renal cancer:9.08e-4 (favourable) Group enriched Tissue enhanced kidney: 53.4;liver: 20.7 heart muscle: 8.5 Cell line enhanced EFO-21: 9.0;Hep G2: 17.6;RPTEC TERT1: 23.2 +PWP2 EHOC-17, PWP2H, UTP1 ENSG00000241945 PWP2 periodic tryptophan protein homolog (yeast) 21 44107290-44131181 Predicted intracellular proteins Evidence at protein level HPA024573 Uncertain Supported Nucleoli
Cytosol Mixed Mixed skin: 5.4 Cell line enhanced CACO-2: 61.4 +PI4KA PI4K-ALPHA, pi4K230, PIK4CA ENSG00000241973 Phosphatidylinositol 4-kinase alpha 22 20707691-20859417 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009092, HPA075515 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:7.22e-5 (favourable), Lung cancer:5.24e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 113.6 Expressed in all +AKAP2 AKAP-KL, DKFZp564L0716, KIAA0920, MISP2, PRKA2 ENSG00000241978 A-kinase anchoring protein 2 9 110048598-110172512 Predicted intracellular proteins Evidence at protein level Not detected Expressed in all placenta: 123.7 Mixed +KIR3DL3 CD158z, KIR3DL7, KIR44, KIRC1 ENSG00000242019 Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3 19 54724479-54736536 Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +HYPK C15orf63, FLJ20431, HSPC136 ENSG00000242028 Huntingtin interacting protein K 15 43796142-43803043 Predicted intracellular proteins Evidence at protein level HPA055252 Uncertain Supported Nucleoplasm
Microtubules Mixed Mixed testis: 6.3 Mixed +AMACR P504S, RACE ENSG00000242110 Alpha-methylacyl-CoA racemase 5 33986178-34008108 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB001809, HPA019527, HPA020912 Enhanced Supported Vesicles
Plasma membrane Colorectal cancer:7.11e-4 (favourable) Expressed in all Expressed in all kidney: 135.3 Expressed in all +MTFP1 HSPC242, MTP18 ENSG00000242114 Mitochondrial fission process 1 22 30425530-30429053 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA077396 Approved Mitochondria Expressed in all Expressed in all epididymis: 19.2 Expressed in all +RP11-231I13.2 ENSG00000242120 3 70196894-70312726 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +ARHGDIG RHOGDI-3 ENSG00000242173 Rho GDP dissociation inhibitor gamma 16 268727-283010 Predicted intracellular proteins Evidence at protein level HPA078260 Approved Plasma membrane
Cytosol Mixed Tissue enhanced cerebral cortex: 131.1;duodenum: 44.2 small intestine: 17.9 Cell line enhanced HEK 293: 24.6;MCF7: 27.2;SCLC-21H: 14.0;SH-SY5Y: 15.7 +OR51B5 ENSG00000242180 Olfactory receptor family 51 subfamily B member 5 11 5342586-5343524 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA063124 Uncertain Not detected Not detected epididymis,testis: 0.2 Group enriched 7 K-562: 5.4;U-2197: 1.5 +TCP10L PRED77 ENSG00000242220 T-complex 10-like 21 32574841-32587373 Predicted intracellular proteins Evidence at protein level HPA044709 Approved Tissue enhanced Tissue enriched 27 testis: 285.4 liver: 10.7 Cell line enriched 7 SCLC-21H: 14.6 +PSG2 CEA, PSBG2, PSG1, PSGGB ENSG00000242221 Pregnancy specific beta-1-glycoprotein 2 19 43064211-43083045 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 222 placenta: 343.4 smooth muscle: 1.5 Group enriched 6 BJ: 9.2;fHDF/TERT166: 18.4;HBF TERT88: 34.3;U-2197: 42.9 +ARFGAP3 ARFGAP1 ENSG00000242247 ADP ribosylation factor GTPase activating protein 3 22 42796502-42858106 Predicted intracellular proteins Evidence at protein level HPA000638 Approved Supported Golgi apparatus
Cytosol Endometrial cancer:8.97e-6 (favourable), Thyroid cancer:2.65e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 112.5 Expressed in all +BGLAP OCN ENSG00000242252 Bone gamma-carboxyglutamate protein 1 156241962-156243321 FDA approved drug targets, Predicted secreted proteins Evidence at protein level Mixed Mixed skin: 2.1 Cell line enhanced U-87 MG: 2.8 +C22orf39 MGC74441 ENSG00000242259 Chromosome 22 open reading frame 39 22 19351368-19448232 Predicted intracellular proteins Evidence at protein level HPA073701 Approved Endoplasmic reticulum Renal cancer:1.44e-4 (favourable), Endometrial cancer:2.16e-4 (favourable) Expressed in all Expressed in all thyroid gland: 52.1 Expressed in all +PEG10 HB-1, KIAA1051, Mar2, Mart2, MEF3L, RGAG3 ENSG00000242265 Paternally expressed 10 7 94656325-94669695 Predicted intracellular proteins Evidence at protein level HPA021324, HPA029915, HPA051038 Enhanced Supported Nucleus
Cytosol Endometrial cancer:8.15e-4 (unfavourable) Expressed in all Group enriched 5 adrenal gland: 224.2;placenta: 663.3 ovary: 80.7 Cell line enhanced AF22: 763.0;HAP1: 1045.3;Hep G2: 547.0;SCLC-21H: 574.7 +CT47A2 CT47.2 ENSG00000242362 Cancer/testis antigen family 47, member A2 X 120977606-120980928 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 20 testis: 2.0 all non-specific tissues: 0.0 Not detected +UGT1A8 UGT1H ENSG00000242366 UDP glucuronosyltransferase family 1 member A8 2 233617645-233773310 Enzymes, Predicted membrane proteins Evidence at protein level Tissue enhanced Tissue enhanced colon: 16.0;gallbladder: 10.3;rectum: 9.7;urinary bladder: 22.7 small intestine: 4.9 Cell line enriched 53 RT4: 96.7 +EIF6 b(2)gcn, EIF3A, ITGB4BP, p27BBP ENSG00000242372 Eukaryotic translation initiation factor 6 20 35278907-35284985 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040873 Enhanced Supported Nucleoplasm Liver cancer:7.25e-5 (unfavourable) Expressed in all Expressed in all esophagus: 173.2 Expressed in all +RBMY1E ENSG00000242389 RNA binding motif protein, Y-linked, family 1, member E Y 21903618-21918067 Predicted intracellular proteins Evidence at protein level HPA001534, HPA053147 Supported Not detected Tissue enriched 22 testis: 2.2 all non-specific tissues: 0.0 Cell line enriched 8 U-266/84: 1.6 +PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 Protocadherin gamma subfamily C, 4 5 141484997-141512979 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Tissue enriched Tissue enriched 11 cerebral cortex: 16.3 adrenal gland: 1.4 Cell line enhanced REH: 8.3;SCLC-21H: 8.7;SH-SY5Y: 15.1 +GTF2A1L ALF ENSG00000242441 General transcription factor IIA subunit 1 like 2 48617798-48733148 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 66 testis: 105.4 endometrium,gallbladder: 1.5 Cell line enhanced ASC diff: 1.0 +MRPL20 FLJ10024 ENSG00000242485 Mitochondrial ribosomal protein L20 1 1401908-1407313 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047074 Supported Supported Mitochondria Expressed in all Expressed in all epididymis: 156.4 Expressed in all +ARPIN C15orf38, MGC61550 ENSG00000242498 Actin-related protein 2/3 complex inhibitor 15 89895006-89912956 Predicted intracellular proteins Evidence at protein level HPA040513, HPA047173, HPA052278 Uncertain Renal cancer:4.19e-4 (favourable) Expressed in all Mixed parathyroid gland: 31.0 Mixed +UGT1A10 UGT1J ENSG00000242515 UDP glucuronosyltransferase family 1 member A10 2 233636454-233773305 Cancer-related genes, Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Pancreatic cancer:4.55e-4 (unfavourable) Tissue enhanced Tissue enhanced colon: 49.7;duodenum: 80.9;small intestine: 59.1 rectum: 39.6 Cell line enriched 108 RT4: 416.9 +SERPINB10 bomapin, PI10 ENSG00000242550 Serpin family B member 10 18 63897174-63936111 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015480, HPA059582 Uncertain Not detected Tissue enriched 32 bone marrow: 50.1 skin: 1.5 Cell line enriched 7 U-937: 82.6 +HLA-DMB D6S221E, RING7 ENSG00000242574 Major histocompatibility complex, class II, DM beta 6 32934629-32941070 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012298 Supported Endometrial cancer:3.89e-5 (favourable) Expressed in all Tissue enhanced thyroid gland: 29.3 spleen: 12.0 Group enriched 11 CAPAN-2: 5.2;Daudi: 6.1;EFO-21: 3.6;U-266/70: 2.3;U-698: 7.1 +DECR2 PDCR, SDR17C1 ENSG00000242612 2,4-dienoyl-CoA reductase 2 16 401826-412487 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047631 Approved Peroxisomes Expressed in all Mixed duodenum: 10.5 Mixed +GNG10 ENSG00000242616 G protein subunit gamma 10 9 111661335-111670246 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Head and neck cancer:3.21e-5 (unfavourable) Expressed in all Expressed in all appendix: 90.3 Expressed in all +CNTF HCNTF ENSG00000242689 Ciliary neurotrophic factor 11 58622673-58625733 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019654 Uncertain Approved Vesicles Mixed Tissue enhanced fallopian tube: 7.7 bone marrow: 4.3 Mixed +CCDC169 C13orf38, LOC728591, RP11-251J8.1 ENSG00000242715 Coiled-coil domain containing 169 13 36222008-36297840 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 16 testis: 78.5 parathyroid gland: 4.9 Cell line enhanced HL-60: 14.2 +RGAG4 KIAA2001, Mar5, Mart5 ENSG00000242732 Retrotransposon gag domain containing 4 X 72127110-72131901 Predicted intracellular proteins Evidence at transcript level HPA003652 Approved Approved Nucleoplasm Pancreatic cancer:3.41e-4 (favourable), Lung cancer:7.30e-4 (favourable) Expressed in all Mixed thyroid gland: 4.1 Cell line enhanced AF22: 3.7;AN3-CA: 3.9;SCLC-21H: 5.9;SH-SY5Y: 7.4 +AP5Z1 KIAA0415, SPG48, zeta ENSG00000242802 Adaptor related protein complex 5 zeta 1 subunit 7 4775622-4794312 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035693 Supported Supported Nucleoplasm
Nuclear speckles Liver cancer:1.35e-5 (unfavourable) Expressed in all Mixed spleen: 15.4 Expressed in all +ZNF709 FLJ38281 ENSG00000242852 Zinc finger protein 709 19 12461184-12513854 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA045573, HPA053153 Uncertain Approved Nucleoplasm Not detected Tissue enhanced testis: 14.0 thyroid gland: 4.8 Mixed +STRC DFNB16 ENSG00000242866 Stereocilin 15 43599398-43618800 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048083 Enhanced Not detected Tissue enhanced cerebral cortex: 1.4;epididymis: 1.6;testis: 1.7 skin: 0.8 Not detected +RBMY1B ENSG00000242875 RNA binding motif protein, Y-linked, family 1, member B Y 21511338-21549094 Predicted intracellular proteins Evidence at protein level HPA001534, HPA053147 Supported Not detected Tissue enriched 33 testis: 3.3 all non-specific tissues: 0.0 Not detected +ERVW-1 ERVWE1, HERV-7q, HERV-W, HERV-W-ENV, HERVW ENSG00000242950 Endogenous retrovirus group W member 1 7 92468380-92477986 Predicted membrane proteins, Transporters Evidence at protein level Tissue enriched Tissue enriched 12 placenta: 77.2 testis: 6.5 Cell line enriched 48 BEWO: 81.7 +EIF4EBP3 4E-BP3 ENSG00000243056 Eukaryotic translation initiation factor 4E binding protein 3 5 140547666-140549578 Predicted intracellular proteins Evidence at protein level HPA045537 Uncertain Renal cancer:3.10e-4 (favourable) Expressed in all Expressed in all fallopian tube: 59.8 Mixed +PRAMEF4 RP5-845O24.6 ENSG00000243073 PRAME family member 4 1 12879224-12886201 Predicted intracellular proteins Evidence at transcript level Tissue enriched Not detected all non-specific tissues: 0.0 Not detected +PSG11 MGC22484, PSG13, PSG14 ENSG00000243130 Pregnancy specific beta-1-glycoprotein 11 19 43007656-43026512 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042240, HPA046327 Enhanced Not detected Tissue enriched 77 placenta: 74.1 smooth muscle: 0.9 Cell line enriched 29 U-2197: 15.6 +UGT1A3 UGT1C ENSG00000243135 UDP glucuronosyltransferase family 1 member A3 2 233729108-233773299 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 7 liver: 38.2 small intestine: 5.6 Cell line enriched 11 HaCaT: 10.9 +PSG4 ENSG00000243137 Pregnancy specific beta-1-glycoprotein 4 19 43192702-43207299 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046327 Approved Mixed Group enriched 8 parathyroid gland: 244.5;placenta: 193.0 colon: 28.0 Group enriched 7 fHDF/TERT166: 409.2;U-2197: 129.9 +MRPL33 C2orf1, RPL33L ENSG00000243147 Mitochondrial ribosomal protein L33 2 27771717-27988087 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA066872 Approved Liver cancer:1.66e-4 (unfavourable), Head and neck cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 586.9 Expressed in all +MICAL3 KIAA0819 ENSG00000243156 Microtubule associated monooxygenase, calponin and LIM domain containing 3 22 17787649-18024559 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000639, HPA003421, HPA034882 Uncertain Enhanced Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 71.2 Expressed in all +PPAN-P2RY11 ENSG00000243207 PPAN-P2RY11 readthrough 19 10106223-10114780 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014232 Uncertain Not detected Mixed fallopian tube: 2.4 Mixed +PCDHAC2 PCDH-ALPHA-C2 ENSG00000243232 Protocadherin alpha subfamily C, 2 5 140966235-141012344 Predicted membrane proteins Evidence at transcript level HPA076190 Approved Nucleoplasm
Mitochondria Mixed Tissue enriched 7 parathyroid gland: 92.5 cerebral cortex: 14.1 Cell line enhanced A549: 11.3;AN3-CA: 57.4;SH-SY5Y: 11.6 +STON1 SBLF, stoned-b1 ENSG00000243244 Stonin 1 2 48529383-48598513 Predicted intracellular proteins Evidence at protein level HPA005715 Uncertain Renal cancer:4.69e-4 (unfavourable) Mixed Mixed smooth muscle: 37.4 Cell line enhanced ASC diff: 16.3;ASC TERT1: 20.1;HSkMC: 26.3 +PRAF2 JM4, Yip6a ENSG00000243279 PRA1 domain family member 2 X 49071156-49074071 Predicted membrane proteins, Transporters Evidence at protein level HPA002859, HPA005504, CAB011655 Enhanced Approved Endoplasmic reticulum
Vesicles Liver cancer:1.66e-6 (unfavourable), Pancreatic cancer:4.88e-6 (favourable), Renal cancer:5.83e-6 (unfavourable), Lung cancer:2.81e-4 (favourable), Cervical cancer:7.42e-4 (favourable) Expressed in all Expressed in all epididymis: 185.0 Expressed in all +VSIG8 ENSG00000243284 V-set and immunoglobulin domain containing 8 1 159854316-159862657 Predicted membrane proteins Evidence at protein level HPA023219 Uncertain Group enriched Group enriched 6 skin: 13.6;tonsil: 5.8 kidney: 1.7 Not detected +C7orf73 PL-5283 ENSG00000243317 Chromosome 7 open reading frame 73 7 135662496-135693418 Predicted secreted proteins Evidence at protein level HPA065565 Approved Mitochondria Ovarian cancer:2.95e-4 (favourable) Expressed in all Expressed in all thyroid gland: 53.3 Expressed in all +KCTD7 CLN14, EPM3, FLJ32069 ENSG00000243335 Potassium channel tetramerization domain containing 7 7 66628767-66649067 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Pancreatic cancer:3.26e-4 (favourable), Colorectal cancer:8.07e-4 (unfavourable) Expressed in all Mixed testis: 32.9 Expressed in all +EFNA4 EPLG4, LERK4 ENSG00000243364 Ephrin A4 1 155063731-155069553 Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB021350, HPA064952 Approved Uncertain Nucleus
Vesicles Liver cancer:1.00e-5 (unfavourable), Stomach cancer:3.60e-5 (favourable), Renal cancer:3.14e-4 (unfavourable) Expressed in all Mixed skin: 24.5 Expressed in all +TICAM2 TICAM-2, TIRP, TRAM ENSG00000243414 Toll like receptor adaptor molecule 2 5 115578650-115602479 Predicted intracellular proteins Evidence at protein level Not detected Mixed cervix, uterine: 6.1 Cell line enhanced HDLM-2: 32.3;U-138 MG: 20.3;U-2197: 20.8 +AF165138.7 ENSG00000243440 21 14591930-14658821 Predicted intracellular proteins Evidence at transcript level HPA046639 Uncertain Not detected Not detected appendix: 0.7 Group enriched 7 HEL: 3.4;NTERA-2: 2.3 +PALM2 ENSG00000243444 Paralemmin 2 9 109640788-109946703 Predicted intracellular proteins Evidence at protein level HPA074153 Approved Plasma membrane Not detected Tissue enhanced cerebral cortex: 9.8 liver: 3.6 Cell line enhanced RH-30: 19.4 +C4orf48 ENSG00000243449 Chromosome 4 open reading frame 48 4 2041993-2043970 Predicted secreted proteins Evidence at protein level HPA052447 Uncertain Supported Cytosol Expressed in all Tissue enhanced cerebral cortex: 22.1 testis: 11.2 Cell line enhanced HEK 293: 145.6;PC-3: 318.4 +NAT6 FUS2 ENSG00000243477 N-acetyltransferase 6 3 50296402-50299421 Predicted intracellular proteins Evidence at protein level HPA039576 Approved Renal cancer:1.71e-4 (favourable), Breast cancer:3.62e-4 (favourable) Expressed in all Expressed in all testis: 45.8 Expressed in all +AMY2A AMY2 ENSG00000243480 Amylase, alpha 2A (pancreatic) 1 103616811-103625780 Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level HPA045394, HPA045399, CAB045960, HPA046980 Enhanced Tissue enriched Tissue enriched 313 pancreas: 31329.4 ovary: 99.9 Not detected +KRTAP10-11 KAP10.11, KAP18.11, KRTAP18-11, KRTAP18.11 ENSG00000243489 Keratin associated protein 10-11 21 44646414-44647650 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +TNFRSF6B DcR3, M68, TR6 ENSG00000243509 TNF receptor superfamily member 6b 20 63696668-63698684 Predicted secreted proteins Evidence at protein level HPA047154 Uncertain Not detected Tissue enriched 6 appendix: 19.0 tonsil: 3.1 Cell line enhanced HBEC3-KT: 20.3;RPTEC TERT1: 82.5;TIME: 57.1 +WFDC6 C20orf171, dJ461P17.11, WAP6 ENSG00000243543 WAP four-disulfide core domain 6 20 45534196-45539495 Predicted secreted proteins Evidence at transcript level Tissue enhanced Group enriched 16 epididymis: 323.7;testis: 83.8 fallopian tube: 12.5 Cell line enriched 7 U-87 MG: 2.6 +UPK3B FLJ32198, MGC10902, p35, UPIIIb ENSG00000243566 Uroplakin 3B 7 76510428-76516521 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA010506 Approved Approved Nucleus
Vesicles
Cytosol Group enriched Group enriched 11 esophagus: 12.4;lung: 29.8;urinary bladder: 11.0 tonsil: 1.6 Group enriched 8 A549: 12.0;CAPAN-2: 41.9;HaCaT: 8.6;RT4: 26.3;T-47d: 25.4 +AP000322.53 ENSG00000243627 21 34418715-34423966 Predicted membrane proteins Evidence at transcript level HPA029085 Uncertain Not detected Group enriched 7 breast: 1.5;fallopian tube: 1.4;kidney: 4.3 skin: 0.3 Not detected +IL10RB CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2 ENSG00000243646 Interleukin 10 receptor subunit beta 21 33266358-33310187 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB020670, HPA047550 Approved Approved Cytosol Renal cancer:5.62e-9 (unfavourable) Expressed in all Expressed in all placenta: 90.0 Expressed in all +CFB BF, BFD, H2-Bf ENSG00000243649 Complement factor B 6 31945650-31952084 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000951, HPA001817, HPA001832, CAB016381 Supported Approved Endoplasmic reticulum
Vesicles
Cell Junctions Renal cancer:1.53e-5 (unfavourable), Breast cancer:2.76e-5 (favourable) Expressed in all Tissue enriched 21 liver: 285.9 stomach: 13.8 Cell line enhanced CAPAN-2: 6.6;fHDF/TERT166: 9.6;HSkMC: 14.1 +ZNF487 KRBO1, ZNF487P ENSG00000243660 Zinc finger protein 487 10 43436841-43483179 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA037820 Approved Nucleoplasm
Nuclear membrane
Cytosol Mixed Tissue enriched 5 testis: 51.4 fallopian tube: 9.9 Mixed +WDR92 FLJ31741, Monad ENSG00000243667 WD repeat domain 92 2 68122936-68157560 Predicted intracellular proteins Evidence at protein level HPA035335, HPA035336 Approved Approved Nucleoplasm Mixed Mixed epididymis: 19.8 Expressed in all +NME2 NDPKB, NM23-H2 ENSG00000243678 NME/NM23 nucleoside diphosphate kinase 2 17 51165435-51171747 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA041113 Approved Renal cancer:1.55e-6 (unfavourable), Cervical cancer:4.74e-4 (unfavourable), Liver cancer:7.09e-4 (unfavourable) Expressed in all Expressed in all breast: 512.0 Expressed in all +PLA2G4B cPLA2-beta, HsT16992 ENSG00000243708 Phospholipase A2 group IVB 15 41837775-41848147 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Not detected Tissue enhanced skin: 36.3 esophagus: 14.1 Cell line enhanced RT4: 5.9 +LEFTY1 LEFTB, LEFTYB ENSG00000243709 Left-right determination factor 1 1 225886282-225911382 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA047883, HPA056210 Approved Renal cancer:2.48e-6 (unfavourable) Tissue enhanced Tissue enhanced colon: 58.4;pancreas: 20.4;rectum: 35.2 appendix: 9.6 Cell line enriched 7 NTERA-2: 50.6 +CFAP57 FLJ32000, WDR65 ENSG00000243710 Cilia and flagella associated protein 57 1 43172149-43254358 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002736, HPA028623 Enhanced Approved Cytosol Endometrial cancer:6.02e-4 (favourable) Mixed Group enriched 8 fallopian tube: 35.6;testis: 27.7 lung: 3.7 Cell line enhanced HaCaT: 2.5 +NPIPB5 ENSG00000243716 Nuclear pore complex interacting protein family member B5 16 22479121-22536521 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Mixed Expressed in all skin: 261.4 Expressed in all +TTC4 FLJ41930, MGC5097 ENSG00000243725 Tetratricopeptide repeat domain 4 1 54715822-54742657 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041608, HPA042459 Approved Expressed in all Expressed in all cervix, uterine: 13.3 Expressed in all +OR5V1 hs6M1-21 ENSG00000243729 Olfactory receptor family 5 subfamily V member 1 6 29355230-29431967 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA046707 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +TMEM35B ZMYM6NB ENSG00000243749 Transmembrane protein 35B 1 34981535-34985353 Predicted membrane proteins Evidence at protein level HPA051024 Uncertain Approved Nucleus
Nucleoli Expressed in all Expressed in all placenta: 91.7 Mixed +KIR2DL3 CD158B2, cl-6, nkat2, nkat2a, nkat2b, p58 ENSG00000243772 Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 19 54738515-54753052 CD markers, Predicted membrane proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +JMJD7 ENSG00000243789 Jumonji domain containing 7 15 41828085-41837581 Predicted intracellular proteins Evidence at protein level HPA005726 Uncertain Approved Cytosol Not detected Expressed in all skin: 28.0 Cell line enhanced RT4: 34.4 +APOBEC3D APOBEC3DE, APOBEC3E, ARP6 ENSG00000243811 Apolipoprotein B mRNA editing enzyme catalytic subunit 3D 22 39021113-39033276 Predicted intracellular proteins Evidence at protein level HPA055116 Uncertain Renal cancer:3.76e-7 (unfavourable), Breast cancer:2.51e-5 (favourable), Cervical cancer:1.31e-4 (favourable), Urothelial cancer:3.01e-4 (favourable), Endometrial cancer:4.47e-4 (favourable) Expressed in all Mixed lymph node: 15.1 Cell line enhanced Karpas-707: 31.5 +OR2A7 HSDJ0798C17 ENSG00000243896 Olfactory receptor family 2 subfamily A member 7 7 144258607-144259722 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA058272 Uncertain Mixed Mixed thyroid gland: 19.9 Cell line enhanced A-431: 12.2;hTCEpi: 5.6;RT4: 5.8;SK-BR-3: 4.8 +TUBA4B FLJ13940, TUBA4 ENSG00000243910 Tubulin alpha 4b 2 219253243-219272188 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 14 fallopian tube: 64.2 lung: 4.5 Not detected +MRPS6 C21orf101, MRP-S6, RPMS6 ENSG00000243927 Mitochondrial ribosomal protein S6 21 34073224-34143034 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA007861, HPA049676 Supported Urothelial cancer:1.06e-5 (favourable) Expressed in all Expressed in all thyroid gland: 121.0 Expressed in all +ZNF512 KIAA1805 ENSG00000243943 Zinc finger protein 512 2 27582969-27623215 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031430 Approved Enhanced Nucleus Lung cancer:5.08e-9 (favourable), Endometrial cancer:5.10e-4 (unfavourable), Pancreatic cancer:5.19e-4 (favourable), Breast cancer:9.79e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 45.7 Mixed +GSTA1 ENSG00000243955 Glutathione S-transferase alpha 1 6 52791664-52803910 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004342, HPA048934, HPA053817 Supported Supported Cytosol Renal cancer:3.71e-4 (unfavourable), Lung cancer:8.66e-4 (favourable) Group enriched Tissue enhanced adrenal gland: 1136.4;kidney: 1310.9;liver: 1757.6 small intestine: 1002.9 Cell line enriched 11 Hep G2: 245.8 +RGAG1 KIAA1318, Mar9, Mart9 ENSG00000243978 Retrotransposon gag domain containing 1 X 110358816-110456334 Predicted intracellular proteins Evidence at protein level HPA001242 Enhanced Not detected Tissue enriched 18 testis: 19.5 placenta: 1.0 Cell line enhanced hTEC/SVTERT24-B: 2.0;U-2197: 1.4;U-87 MG: 1.1 +ACY1 ENSG00000243989 Aminoacylase 1 3 51983278-51989202 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003695, HPA036174, HPA036175 Enhanced Renal cancer:2.93e-4 (favourable), Urothelial cancer:6.77e-4 (favourable) Expressed in all Group enriched 5 duodenum: 130.8;kidney: 356.0;liver: 114.9;small intestine: 103.3 parathyroid gland: 35.0 Mixed +NFS1 IscS, NifS ENSG00000244005 NFS1, cysteine desulfurase 20 35668055-35699359 Enzymes, Predicted intracellular proteins Evidence at protein level CAB034314, HPA051801, HPA054755 Enhanced Supported Nucleoplasm
Cytosol Renal cancer:4.72e-6 (favourable) Expressed in all Expressed in all kidney: 43.7 Expressed in all +MT1HL1 MT1P2 ENSG00000244020 Metallothionein 1H like 1 1 237004103-237004418 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 8 heart muscle: 2.8 urinary bladder: 0.3 Not detected +KRTAP19-3 KAP19.3 ENSG00000244025 Keratin associated protein 19-3 21 30491464-30491985 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +DDOST KIAA0115, OST, OST48, WBP1 ENSG00000244038 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit 1 20651767-20661544 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009746, HPA046841, HPA052867 Supported Supported Endoplasmic reticulum Renal cancer:9.05e-7 (unfavourable), Liver cancer:2.64e-5 (unfavourable), Head and neck cancer:4.88e-4 (unfavourable), Endometrial cancer:5.99e-4 (favourable) Expressed in all Expressed in all thyroid gland: 308.3 Expressed in all +TMEM199 C17orf32, MGC45714, VMA12, VPH2 ENSG00000244045 Transmembrane protein 199 17 28357581-28363683 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA027051 Uncertain Liver cancer:1.54e-4 (unfavourable), Endometrial cancer:5.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 19.3 Expressed in all +LCE3C LEP15, SPRL3A ENSG00000244057 Late cornified envelope 3C 1 152600662-152601086 Predicted intracellular proteins Evidence at protein level Group enriched Tissue enriched 10 tonsil: 22.5 skin: 2.1 Not detected +GSTA2 GST2 ENSG00000244067 Glutathione S-transferase alpha 2 6 52750089-52763569 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004342, HPA048934, HPA053817 Supported Supported Cytosol Renal cancer:1.17e-4 (unfavourable) Group enriched Group enriched 5 kidney: 651.7;liver: 986.1 gallbladder: 155.6 Group enriched 17 CACO-2: 19.6;Hep G2: 12.5 +SPRR2F ENSG00000244094 Small proline rich protein 2F 1 153112114-153113515 Predicted intracellular proteins Evidence at protein level Tissue enhanced Group enriched 9 esophagus: 167.0;ovary: 83.7;tonsil: 63.0 testis: 11.8 Cell line enriched 9 K-562: 2.4 +DNAJC25-GNG10 ENSG00000244115 DNAJC25-GNG10 readthrough 9 111631386-111670229 Predicted secreted proteins Evidence at transcript level Not detected Mixed prostate: 25.3 Expressed in all +UGT1A7 UGT1G ENSG00000244122 UDP glucuronosyltransferase family 1 member A7 2 233681938-233773299 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Group enriched Tissue enriched 13 esophagus: 61.4 tonsil: 4.6 Cell line enriched 21 SiHa: 118.8 +P2RY11 P2Y11 ENSG00000244165 Purinergic receptor P2Y11 19 10111538-10115372 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA014232 Approved Urothelial cancer:1.77e-4 (favourable) Expressed in all Mixed lymph node: 7.2 Mixed +TMEM141 MGC14141 ENSG00000244187 Transmembrane protein 141 9 136791355-136793257 Predicted membrane proteins Evidence at protein level HPA014615, HPA050244 Approved Supported Cell Junctions
Mitochondria Renal cancer:6.63e-4 (favourable) Expressed in all Expressed in all prostate: 199.4 Expressed in all +GS1-259H13.2 ENSG00000244219 7 99598066-99610813 Predicted membrane proteins Evidence at transcript level Mixed Tissue enriched 54 testis: 234.7 epididymis: 4.3 Cell line enhanced Karpas-707: 8.5 +IFITM10 ENSG00000244242 Interferon induced transmembrane protein 10 11 1732410-1750591 Predicted membrane proteins Evidence at transcript level Expressed in all Tissue enhanced adrenal gland: 3.4 bone marrow,seminal vesicle: 0.7 Cell line enhanced CAPAN-2: 2.6;MCF7: 3.3;SH-SY5Y: 10.4;U-87 MG: 5.6 +XXbac-BPG116M5.17 ENSG00000244255 6 31927698-31952048 Predicted secreted proteins Evidence at protein level HPA000951, HPA001817, HPA001832 Approved Not detected Tissue enhanced liver: 3.3;lung: 2.9 spleen: 1.2 Not detected +DBNDD2 C20orf35, HSMNP1 ENSG00000244274 Dysbindin domain containing 2 20 45406057-45410610 Predicted intracellular proteins Evidence at protein level HPA043991 Enhanced Approved Nucleoplasm
Cytosol Mixed Expressed in all cerebral cortex: 460.2 Mixed +LY6G6D C6orf23, G6D, Ly6-D, MEGT1, NG25 ENSG00000244355 Lymphocyte antigen 6 family member G6D 6 31715356-31717804 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054412 Uncertain Tissue enriched Tissue enhanced seminal vesicle: 2.0 prostate: 0.8 Cell line enhanced HEL: 1.6 +KRTAP19-7 KAP19.7 ENSG00000244362 Keratin associated protein 19-7 21 30560875-30561314 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +RBMY1D ENSG00000244395 RNA binding motif protein, Y-linked, family 1, member D Y 21880076-21894526 Predicted intracellular proteins Evidence at protein level HPA001534, HPA053147 Supported Not detected Not detected testis: 0.2 Not detected +ETV5 ERM ENSG00000244405 ETS variant 5 3 186046308-186110318 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009590, HPA063065 Approved Supported Nucleoplasm Liver cancer:7.85e-9 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 114.5 cerebral cortex: 74.7 Cell line enhanced SK-MEL-30: 141.2 +KRTAP5-7 KRTAP5-3, KRTAP5.7 ENSG00000244411 Keratin associated protein 5-7 11 71527267-71528674 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced testis: 1.8 epididymis: 0.5 Cell line enriched 10 RT4: 1.3 +CFHR1 CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2 ENSG00000244414 Complement factor H related 1 1 196819757-196832189 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA038915, HPA038922, HPA040726 Supported Approved Vesicles Liver cancer:8.71e-6 (favourable) Tissue enriched Tissue enriched 147 liver: 1057.6 lymph node: 7.1 Cell line enhanced HL-60: 1.5;U-266/70: 1.9 +RBM12 HRIHFB2091, KIAA0765, SWAN ENSG00000244462 RNA binding motif protein 12 20 35648925-35664956 Predicted intracellular proteins Evidence at protein level HPA043258, HPA043621 Enhanced Enhanced Nucleoplasm Liver cancer:1.54e-4 (unfavourable) Expressed in all Expressed in all ovary: 47.6 Expressed in all +UGT1A4 HUG-BR2, UGT1D ENSG00000244474 UDP glucuronosyltransferase family 1 member A4 2 233718778-233773299 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Tissue enriched Tissue enriched 31 liver: 212.3 duodenum: 6.7 Not detected +ERVFRD-1 envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2 ENSG00000244476 Endogenous retrovirus group FRD member 1 6 11102489-11111732 Predicted membrane proteins, Transporters Evidence at protein level Not detected Group enriched 32 parathyroid gland: 30.4;placenta: 51.8 epididymis: 1.2 Cell line enriched 34 BEWO: 8.9 +LILRA6 CD85b, ILT8, LILRB6 ENSG00000244482 Leukocyte immunoglobulin like receptor A6 19 54236592-54242791 Predicted membrane proteins Evidence at protein level Mixed Tissue enhanced adipose tissue: 1.9;appendix: 1.9;smooth muscle: 1.9;spleen: 1.9 bone marrow: 1.0 Not detected +SCARF2 HUMZD58C02, SREC-II, SREC2 ENSG00000244486 Scavenger receptor class F member 2 22 20424815-20437826 Disease related genes, Predicted membrane proteins Evidence at protein level HPA035079 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:2.78e-5 (unfavourable), Urothelial cancer:4.28e-4 (unfavourable) Expressed in all Mixed seminal vesicle: 6.7 Cell line enhanced SH-SY5Y: 30.9;U-138 MG: 39.3;U-2 OS: 43.6 +APOBEC3C APOBEC1L, ARDC2, ARDC4, ARP5, bK150C2.3, PBI ENSG00000244509 Apolipoprotein B mRNA editing enzyme catalytic subunit 3C 22 39014083-39020352 Predicted intracellular proteins Evidence at protein level CAB033048, HPA071523 Approved Approved Intermediate filaments Renal cancer:8.91e-10 (unfavourable), Cervical cancer:1.08e-5 (favourable) Expressed in all Mixed fallopian tube: 84.8 Mixed +KRTAP4-2 KAP4.2 ENSG00000244537 Keratin associated protein 4-2 17 41177446-41178208 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +RAD21L1 dJ545L17.2, RAD21L ENSG00000244588 RAD21 cohesin complex component like 1 20 1226056-1296421 Predicted intracellular proteins Evidence at transcript level HPA053282 Approved Not detected Tissue enriched 77 testis: 21.7 seminal vesicle: 0.2 Cell line enhanced BJ hTERT+: 1.2;TIME: 1.2 +CCDC13 FLJ25467 ENSG00000244607 Coiled-coil domain containing 13 3 42692663-42773253 Predicted intracellular proteins Evidence at protein level HPA047429 Approved Supported Centrosome Mixed Tissue enhanced fallopian tube: 7.6;testis: 6.8 cerebral cortex: 1.5 Not detected +ASPRV1 FLJ25084, SASPase, Taps ENSG00000244617 Aspartic peptidase, retroviral-like 1 2 69960089-69962265 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA034809, HPA034810 Enhanced Group enriched Tissue enriched 13 skin: 286.1 breast: 22.6 Cell line enhanced REH: 4.5 +OR2AE1 OR2AE2 ENSG00000244623 Olfactory receptor family 2 subfamily AE member 1 7 99875987-99877057 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA042957 Uncertain Not detected Not detected parathyroid gland: 0.2 Not detected +KRTAP20-1 KAP20.1 ENSG00000244624 Keratin associated protein 20-1 21 30616425-30616699 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.1 Not detected +UBE2V1 CROC-1, CROC1, UBE2V, UEV-1, UEV1A ENSG00000244687 Ubiquitin conjugating enzyme E2 V1 20 50081124-50115959 Predicted intracellular proteins Evidence at protein level HPA052535, HPA053186 Enhanced Nucleoplasm Renal cancer:4.58e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 109.7 Expressed in all +CTAGE8 ENSG00000244693 CTAGE family member 8 7 144266701-144269288 Predicted membrane proteins Evidence at protein level HPA000387, HPA000922 Uncertain Not detected Tissue enhanced thyroid gland: 11.4 skin: 9.1 Cell line enhanced A-431: 9.7;HaCaT: 5.8;RT4: 5.7;SiHa: 6.7 +PTCHD4 C6orf138, dJ402H5.2, FLJ41841 ENSG00000244694 Patched domain containing 4 6 47878028-48068689 Predicted membrane proteins Evidence at transcript level HPA041276 Uncertain Approved Plasma membrane
Cytosol Renal cancer:1.49e-6 (favourable) Group enriched Mixed seminal vesicle: 2.8 Cell line enhanced AF22: 17.0;BEWO: 22.0;Hep G2: 27.0;LHCN-M2: 15.3;TIME: 16.1;WM-115: 16.7 +C4A C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG ENSG00000244731 Complement C4A (Rodgers blood group) 6 31982024-32002681 Blood group antigen proteins, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB009811, CAB032603, HPA046356, HPA048287, HPA050103 Approved Tissue enhanced Tissue enhanced liver: 46.1 thyroid gland: 28.2 Group enriched 8 HDLM-2: 49.4;HSkMC: 51.4;U-266/70: 12.8;U-266/84: 23.9 +HBB beta-globin, CD113t-C, HBD ENSG00000244734 Hemoglobin subunit beta 11 5225464-5229395 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB009526, HPA043234 Enhanced Approved Vesicles Expressed in all Tissue enriched 9 bone marrow: 78046.6 placenta: 9082.6 Cell line enhanced HEL: 5.3;SCLC-21H: 5.9;SH-SY5Y: 6.7;U-266/70: 17.4 +CRYBB2 CCA2, CRYB2, CRYB2A ENSG00000244752 Crystallin beta B2 22 25219522-25231869 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043749 Supported Approved Nucleoplasm Mixed Tissue enhanced testis: 1.5 breast,epididymis,lung,thyroid gland: 0.4 Not detected +N4BP2L2 CG005, PFAAP5 ENSG00000244754 NEDD4 binding protein 2 like 2 13 32432417-32538885 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA039338, HPA039434, HPA059327 Approved Approved Nucleoplasm Expressed in all Expressed in all endometrium: 57.6 Expressed in all +ZNF585B FLJ14928, SZFP41 ENSG00000245680 Zinc finger protein 585B 19 37181579-37218153 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA075556 Approved Nucleoplasm
Cytoplasmic bodies Expressed in all Mixed parathyroid gland: 19.7 Mixed +CEBPA C/EBP-alpha, CEBP ENSG00000245848 CCAAT/enhancer binding protein alpha 19 33299934-33302564 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052734, HPA065037, HPA067937 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all adipose tissue: 108.0 Cell line enhanced BEWO: 187.4;THP-1: 270.7;U-937: 100.7 +H2AFJ FLJ10903, MGC921 ENSG00000246705 H2A histone family member J 12 14774383-14778002 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041189 Supported Expressed in all Expressed in all testis: 334.6 Cell line enhanced A549: 232.9;MCF7: 259.0 +UBAP1L ENSG00000246922 Ubiquitin associated protein 1 like 15 65092770-65115197 Predicted intracellular proteins Evidence at protein level HPA065334 Uncertain Nuclear bodies Mixed Mixed cerebral cortex: 1.8 Cell line enhanced SK-MEL-30: 1.9 +PGAM5 BXLBv68, MGC5352 ENSG00000247077 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 12 132710819-132722734 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036978, HPA036979, CAB068215 Enhanced Supported Mitochondria Liver cancer:1.13e-6 (unfavourable) Expressed in all Expressed in all testis: 28.3 Expressed in all +ZCCHC3 C20orf99, dJ1103G7.7 ENSG00000247315 Zinc finger CCHC-type containing 3 20 296968-300321 Predicted intracellular proteins Evidence at protein level HPA042972 Approved Vesicles Pancreatic cancer:1.29e-4 (favourable) Expressed in all Expressed in all placenta: 23.2 Expressed in all +SPTY2D1-AS1 ENSG00000247595 SPTY2D1 antisense RNA 1 11 18588781-18610255 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Mixed Tissue enriched 21 testis: 366.7 skin: 17.2 Mixed +TWF2 A6r, A6RP, PTK9L ENSG00000247596 Twinfilin actin binding protein 2 3 52228610-52239260 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053874 Uncertain Supported Plasma membrane Expressed in all Expressed in all lymph node: 61.2 Expressed in all +MARS2 mtMetRS, SPAX3 ENSG00000247626 Methionyl-tRNA synthetase 2, mitochondrial 2 197705369-197708387 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035589, HPA035590 Uncertain Approved Intermediate filaments
Cytosol Renal cancer:6.14e-5 (favourable), Glioma:1.49e-4 (favourable), Endometrial cancer:3.50e-4 (unfavourable) Expressed in all Expressed in all lymph node: 7.5 Expressed in all +USP51 ENSG00000247746 Ubiquitin specific peptidase 51 X 55484616-55489202 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001942 Uncertain Approved Nucleoli fibrillar center
Cytosol Renal cancer:2.63e-5 (favourable), Ovarian cancer:5.70e-4 (favourable) Mixed Tissue enriched 7 epididymis: 62.9 parathyroid gland: 9.3 Mixed +BCKDHA MSU, OVD1A ENSG00000248098 Branched chain keto acid dehydrogenase E1, alpha polypeptide 19 41397460-41425005 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036640 Supported Renal cancer:5.33e-10 (favourable), Thyroid cancer:3.27e-5 (unfavourable), Head and neck cancer:9.37e-4 (favourable) Expressed in all Expressed in all thyroid gland: 56.0 Expressed in all +INSL3 MGC119818, MGC119819, RLF, RLNL ENSG00000248099 Insulin like 3 19 17816512-17821574 Disease related genes, Predicted secreted proteins Evidence at protein level HPA028615 Enhanced Tissue enriched Tissue enriched 120 testis: 772.7 appendix: 6.4 Cell line enhanced Karpas-707: 4.1;SCLC-21H: 6.1;SH-SY5Y: 5.0 +CTC-295J13.3 ENSG00000248109 5 148221650-148243580 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enhanced epididymis: 1.2 seminal vesicle: 0.9 Cell line enriched 5 HeLa: 479.6 +ADH1C ADH3 ENSG00000248144 Alcohol dehydrogenase 1C (class I), gamma polypeptide 4 99336492-99353027 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047814, HPA060902 Supported Supported Plasma membrane
Cytosol Lung cancer:2.99e-4 (favourable), Liver cancer:4.55e-4 (favourable) Tissue enriched Tissue enhanced duodenum: 508.1;liver: 888.0;stomach: 477.4 colon: 276.3 Cell line enhanced ASC TERT1: 2.5;HSkMC: 7.7 +TRIM39-RPP21 ENSG00000248167 TRIM39-RPP21 readthrough 6 30328907-30346854 Predicted intracellular proteins Evidence at protein level HPA051120 Uncertain Supported Cytosol Not detected Not detected esophagus,testis: 0.2 Not detected +AC037459.4 ENSG00000248235 8 22589274-22602084 Predicted intracellular proteins Evidence at transcript level HPA024667 Uncertain Not detected Tissue enhanced spleen: 3.6 small intestine: 1.9 Cell line enhanced U-2197: 3.5 +APELA ELA, Ende, tdl ENSG00000248329 Apelin receptor early endogenous ligand 4 164877004-164898965 Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced prostate: 6.3 kidney: 2.1 Cell line enriched 5 NTERA-2: 39.7 +CDK11B CDC2L1, CDK11-p110, CDK11-p46, CDK11-p58 ENSG00000248333 Cyclin dependent kinase 11B 1 1635227-1659012 Predicted intracellular proteins Evidence at protein level HPA025061, HPA073626 Approved Approved Nuclear speckles Head and neck cancer:1.14e-4 (favourable) Expressed in all Expressed in all testis: 46.7 Expressed in all +PCDHAC1 ENSG00000248383 Protocadherin alpha subfamily C, 1 5 140926369-141012344 Predicted membrane proteins Evidence at transcript level HPA052775 Approved Nucleus
Nucleoli
Vesicles Not detected Tissue enriched 27 parathyroid gland: 69.4 cerebral cortex: 2.5 Cell line enhanced A549: 5.7;hTCEpi: 5.8;PC-3: 4.2;SCLC-21H: 4.1 +TARM1 ENSG00000248385 T-cell-interacting, activating receptor on myeloid cells 1 19 54069895-54081365 Predicted membrane proteins Evidence at transcript level HPA051022, HPA054401 Uncertain Not detected Not detected gallbladder,spleen: 0.2 Not detected +PRR5-ARHGAP8 ENSG00000248405 PRR5-ARHGAP8 readthrough 22 44702233-44862706 Predicted intracellular proteins Evidence at transcript level Not detected Mixed parathyroid gland,spleen,thyroid gland: 1.2 Cell line enhanced BEWO: 2.9;HEK 293: 3.0;U-266/70: 4.8 +POU5F2 FLJ25680, SPRM-1 ENSG00000248483 POU domain class 5, transcription factor 2 5 93733220-93741637 Predicted intracellular proteins, Transcription factors Evidence at transcript level Not detected Tissue enhanced testis: 2.7 skin: 0.6 Cell line enriched 7 U-2 OS: 3.1 +PCP4L1 IQM1 ENSG00000248485 Purkinje cell protein 4 like 1 1 161258727-161285450 Predicted intracellular proteins Evidence at protein level HPA052833 Enhanced Supported Approved Nucleoplasm
Mitochondria Lung cancer:8.10e-5 (favourable) Group enriched Tissue enhanced cerebral cortex: 45.2;urinary bladder: 39.5 seminal vesicle: 22.7 Cell line enhanced RT4: 10.8;T-47d: 8.2 +ABHD14A DKFZP564O243, DORZ1 ENSG00000248487 Abhydrolase domain containing 14A 3 51971426-51981199 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA038153, HPA056913 Enhanced Vesicles Lung cancer:4.72e-4 (favourable) Expressed in all Expressed in all thyroid gland: 51.0 Expressed in all +TMEM110-MUSTN1 ENSG00000248592 TMEM110-MUSTN1 readthrough 3 52833121-52897562 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA051855 Uncertain Approved Cytosol Not detected Tissue enhanced skeletal muscle: 11.1 adipose tissue: 6.6 Cell line enhanced HDLM-2: 5.2 +RBM14-RBM4 ENSG00000248643 RBM14-RBM4 readthrough 11 66616626-66646469 Predicted intracellular proteins Evidence at protein level HPA047849 Uncertain Approved Nucleoplasm
Cytosol Mixed Not detected epididymis: 0.9 Cell line enhanced NB-4: 5.4 +LY75-CD302 ENSG00000248672 LY75-CD302 readthrough 2 159771851-159904710 Predicted membrane proteins Evidence at protein level HPA049108 Uncertain Not detected Mixed appendix: 2.5 Cell line enhanced CACO-2: 5.5;HDLM-2: 6.5;Karpas-707: 18.3;RT4: 8.7 +CCDC153 LOC283152 ENSG00000248712 Coiled-coil domain containing 153 11 119189638-119196769 Predicted intracellular proteins Evidence at protein level HPA041497 Uncertain Uncertain Cytosol Mixed Tissue enhanced fallopian tube: 17.9 parathyroid gland: 3.8 Cell line enhanced T-47d: 9.5 +RP11-766F14.2 ENSG00000248713 4 99636529-99654648 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 26 skeletal muscle: 24.6 kidney: 0.9 Cell line enhanced RH-30: 1.6 +ACTN3 ENSG00000248746 Actinin alpha 3 (gene/pseudogene) 11 66546395-66563329 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006035 Uncertain Tissue enhanced Tissue enriched 124 skeletal muscle: 556.5 testis: 4.4 Cell line enriched 15 HDLM-2: 12.3 +RP1-130H16.18 ENSG00000248751 22 30285238-30299482 Predicted intracellular proteins Evidence at transcript level Not detected Mixed cerebral cortex: 1.2 Cell line enhanced HSkMC: 1.2;REH: 1.0 +WI2-2373I1.1 ENSG00000248767 7 290170-294422 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.5 Not detected +LINC01207 ENSG00000248771 Long intergenic non-protein coding RNA 1207 4 164754064-164803795 Predicted secreted proteins Evidence at transcript level Tissue enhanced Group enriched 6 cervix, uterine: 4.4;colon: 6.3;duodenum: 10.5;gallbladder: 6.2;prostate: 9.0;rectum: 7.8;small intestine: 12.4 appendix: 1.4 Not detected +TNFSF12-TNFSF13 TWE-PRIL ENSG00000248871 TNFSF12-TNFSF13 readthrough 17 7549099-7561601 Predicted secreted proteins Evidence at transcript level HPA004863, HPA052967 Uncertain Not detected Mixed adipose tissue: 1.9 Cell line enhanced BJ hTERT+: 1.5;U-138 MG: 1.8;U-251 MG: 1.6 +FMN1 DKFZP686C2281, FLJ45135, FMN, LD, MGC125288, MGC125289 ENSG00000248905 Formin 1 15 32765545-33194733 Predicted intracellular proteins Evidence at protein level HPA005465, HPA046786 Approved Supported Nucleoplasm
Cytosol Tissue enriched Tissue enhanced testis: 8.2 cervix, uterine: 4.1 Cell line enhanced RH-30: 13.0;SK-MEL-30: 11.2;T-47d: 11.5 +ATP5J2-PTCD1 ENSG00000248919 ATP5J2-PTCD1 readthrough 7 99419749-99466197 Predicted intracellular proteins Evidence at protein level HPA020106, HPA047679 Uncertain Approved Mitochondria Not detected Mixed prostate: 6.1 Expressed in all +USP17L19 ENSG00000248920 Ubiquitin specific peptidase 17-like family member 19 4 9253378-9255329 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +USP17L22 ENSG00000248933 Ubiquitin specific peptidase 17-like family member 22 4 9267619-9269570 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +XXbac-BPG181M17.5 ENSG00000248993 6 32937364-32953122 Predicted secreted proteins Evidence at protein level HPA012298 Uncertain Not detected Not detected small intestine: 0.4 Not detected +USP17L17 ENSG00000249104 Ubiquitin specific peptidase 17-like family member 17 4 9243879-9245830 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +HAUS5 dgt5, KIAA0841 ENSG00000249115 HAUS augmin like complex subunit 5 19 35612744-35625349 Predicted intracellular proteins Evidence at protein level HPA067250 Approved Renal cancer:4.15e-8 (unfavourable), Liver cancer:2.77e-6 (unfavourable), Endometrial cancer:2.01e-4 (unfavourable), Cervical cancer:7.68e-4 (favourable) Expressed in all Mixed lymph node: 7.1 Expressed in all +EPPIN-WFDC6 SPINLW1-WFDC6 ENSG00000249139 EPPIN-WFDC6 readthrough 20 45536986-45547426 Predicted secreted proteins Evidence at protein level Not detected Group enriched 78 epididymis: 41.7;testis: 58.2 fallopian tube: 0.6 Not detected +RP11-514O12.4 ENSG00000249141 6 166858094-166956124 Predicted intracellular proteins Evidence at transcript level Mixed Mixed epididymis: 2.6 Cell line enhanced NB-4: 2.8 +RP11-432M8.9 ENSG00000249156 5 17610496-17611583 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.1 Cell line enhanced U-2 OS: 1.5 +PCDHA11 CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11 ENSG00000249158 Protocadherin alpha 11 5 140868183-141012344 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA077160 Approved Vesicles
Cell Junctions
Cytoplasmic bodies Not detected Tissue enhanced cerebral cortex: 7.6;parathyroid gland: 3.8 testis: 1.8 Cell line enhanced AN3-CA: 14.0;EFO-21: 7.3;T-47d: 5.0 +AP000304.12 ENSG00000249209 21 33584687-33931607 Predicted intracellular proteins Evidence at protein level HPA039558 Uncertain Not detected Mixed placenta,testis: 1.2 Cell line enhanced U-2 OS: 7.1 +ATP5L2 ATP5K2, dJ222E13.5 ENSG00000249222 ATP synthase, H+ transporting, mitochondrial Fo complex subunit G2 22 42639803-42640601 Predicted intracellular proteins Evidence at protein level HPA044629 Uncertain Supported Mitochondria Not detected Mixed skin: 1.0 Not detected +AC069368.3 ENSG00000249240 15 64841883-64930920 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced spleen: 8.8 appendix: 6.1 Cell line enhanced U-266/84: 21.3 +TMEM150C FLJ12993, TTN3 ENSG00000249242 Transmembrane protein 150C 4 82483170-82562357 Predicted membrane proteins Evidence at protein level HPA052921 Enhanced Renal cancer:4.59e-6 (favourable), Pancreatic cancer:5.68e-4 (favourable), Head and neck cancer:7.87e-4 (favourable) Expressed in all Tissue enhanced epididymis: 181.6 ovary: 43.5 Cell line enhanced AN3-CA: 11.7;MCF7: 27.5;SCLC-21H: 28.6 +AC068533.7 ENSG00000249319 7 66087761-66152277 Predicted intracellular proteins Evidence at transcript level Not detected Mixed parathyroid gland: 8.1 Mixed +NAIP BIRC1, NLRB1 ENSG00000249437 NLR family apoptosis inhibitory protein 5 70968483-71025114 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA042438 Approved Not detected Mixed appendix,spleen: 3.9 Cell line enhanced MOLT-4: 3.0;SiHa: 2.2;T-47d: 2.1 +ZNF286B ZNF286C, ZNF286L, ZNF590 ENSG00000249459 Zinc finger protein 286B 17 18658429-18682262 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA068125 Uncertain Approved Nuclear speckles
Cytosol Mixed Mixed ovary: 2.6 Mixed +ZNF324B FLJ45850 ENSG00000249471 Zinc finger protein 324B 19 58451604-58457833 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023400 Uncertain Approved Nucleoli
Cytosol Pancreatic cancer:2.83e-4 (favourable) Expressed in all Mixed spleen: 4.7 Cell line enhanced HEK 293: 35.2 +SPATS1 FLJ25442, SPATA8, SRSP1 ENSG00000249481 Spermatogenesis associated serine rich 1 6 44342660-44377167 Predicted intracellular proteins Evidence at transcript level HPA030897, HPA049722 Approved Approved Nucleoplasm Not detected Group enriched 5 fallopian tube: 14.2;testis: 45.3 epididymis: 5.6 Cell line enriched 60 SK-MEL-30: 5.9 +CLRN2 ENSG00000249581 Clarin 2 4 17515165-17527104 Predicted membrane proteins, Transporters Evidence at transcript level HPA042407 Uncertain Not detected Not detected testis: 0.3 Not detected +RP4-539M6.19 ENSG00000249590 22 30409255-30428990 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Mixed duodenum: 3.6 Cell line enhanced HBEC3-KT: 13.6;HUVEC TERT2: 10.7 +AP000295.9 ENSG00000249624 21 33246774-33283212 Predicted intracellular proteins Evidence at transcript level Not detected Mixed lung: 1.5 Cell line enhanced HEL: 3.7;MOLT-4: 3.5;RH-30: 4.4 +THEGL ENSG00000249693 Theg spermatid protein-like 4 56530609-56603507 Predicted intracellular proteins Evidence at protein level HPA068093 Uncertain Not detected Tissue enriched 7 testis: 5.6 smooth muscle: 0.8 Not detected +ZNF564 MGC26914 ENSG00000249709 Zinc finger protein 564 19 12525370-12551542 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043998 Uncertain Approved Golgi apparatus Not detected Mixed thyroid gland: 10.5 Mixed +FER1L5 DKFZp434I0121 ENSG00000249715 Fer-1 like family member 5 2 96642737-96704885 Predicted membrane proteins No evidence Not detected Not detected testis: 0.5 Not detected +ECSCR ARIA, ECSM2 ENSG00000249751 Endothelial cell surface expressed chemotaxis and apoptosis regulator 5 139448556-139462743 Predicted membrane proteins Evidence at protein level HPA063337 Enhanced Nucleoplasm
Vesicles
Plasma membrane Expressed in all Mixed placenta: 96.7 Group enriched 104 EFO-21: 322.5;HUVEC TERT2: 736.2;TIME: 536.3 +RP11-15K19.2 ENSG00000249773 7 55887277-55955239 Predicted intracellular proteins Evidence at transcript level HPA047159 Uncertain Not detected Tissue enhanced testis: 3.1 endometrium: 1.3 Mixed +USP17L21 ENSG00000249811 Ubiquitin specific peptidase 17-like family member 21 4 9262872-9264823 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +HS3ST5 3-OST-5 ENSG00000249853 Heparan sulfate-glucosamine 3-sulfotransferase 5 6 114055586-114343045 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021823, HPA064677 Approved Not detected Group enriched 5 cerebral cortex: 6.2;seminal vesicle: 2.2;skeletal muscle: 1.3 adrenal gland: 0.6 Cell line enhanced PC-3: 4.2;RT4: 6.8;SCLC-21H: 19.0 +MTRNR2L5 ENSG00000249860 MT-RNR2-like 5 10 55599303-55600041 Predicted intracellular proteins Evidence at transcript level Not detected Not detected skeletal muscle: 0.3 Not detected +LGALS16 ENSG00000249861 Galectin 16 19 39655894-39660647 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 54 placenta: 7.7 testis: 0.1 Cell line enriched 39 BEWO: 3.9 +RNF103-CHMP3 RNF103-VPS24 ENSG00000249884 RNF103-CHMP3 readthrough 2 86505668-86721122 Predicted intracellular proteins Evidence at protein level HPA015673, HPA073383 Uncertain Not detected Tissue enhanced cerebral cortex: 4.2 bone marrow,heart muscle: 2.7 Mixed +PDCD6 ALG-2, PEF1B ENSG00000249915 Programmed cell death 6 5 271621-353856 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA047221 Approved Cytosol Renal cancer:5.16e-6 (unfavourable), Liver cancer:5.47e-5 (unfavourable), Urothelial cancer:2.19e-4 (favourable) Expressed in all Expressed in all epididymis: 120.9 Expressed in all +GOLGA8K ENSG00000249931 Golgin A8 family member K 15 32392782-32403292 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 11 testis: 6.4 thyroid gland: 0.5 Cell line enhanced U-937: 1.1 +TERB1 CCDC79, FLJ35894 ENSG00000249961 Telomere repeat binding bouquet formation protein 1 16 66754976-66801620 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 22 testis: 25.0 bone marrow: 1.1 Not detected +RP11-548K23.11 ENSG00000249967 10 97584374-97673910 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced parathyroid gland: 1.6 cerebral cortex,seminal vesicle: 0.9 Cell line enhanced AN3-CA: 1.0;EFO-21: 1.1 +TMEM158 p40BBp, RIS1 ENSG00000249992 Transmembrane protein 158 (gene/pseudogene) 3 45224466-45226278 Predicted membrane proteins Evidence at transcript level HPA074974 Approved Renal cancer:5.42e-9 (unfavourable), Prostate cancer:6.43e-5 (favourable) Mixed Tissue enhanced endometrium: 32.6;seminal vesicle: 32.1 smooth muscle: 25.7 Cell line enhanced BJ hTERT+: 274.2;U-138 MG: 137.8;U-87 MG: 447.8 +C15orf38-AP3S2 ENSG00000250021 C15orf38-AP3S2 readthrough 15 89834308-89912882 Predicted intracellular proteins Evidence at protein level HPA040513, HPA047173, HPA049270, HPA052278 Uncertain Approved Vesicles Not detected Expressed in all cerebral cortex: 19.5 Expressed in all +YJEFN3 FLJ44968, hYjeF_N3-19p13.11 ENSG00000250067 YjeF N-terminal domain containing 3 19 19528861-19537581 Predicted intracellular proteins Evidence at protein level HPA060789 Approved Approved Mitochondria Renal cancer:1.30e-7 (unfavourable), Pancreatic cancer:7.25e-4 (favourable) Expressed in all Tissue enhanced cerebral cortex: 15.6;testis: 5.6 epididymis: 3.0 Cell line enhanced BEWO: 8.5;HEK 293: 9.6 +DNAH10OS FLJ45278 ENSG00000250091 Dynein axonemal heavy chain 10 opposite strand 12 123926424-123934984 Predicted intracellular proteins Evidence at transcript level HPA039786 Uncertain Mixed Tissue enhanced cerebral cortex: 4.0 kidney: 1.6 Mixed +PCDHA10 CNR8, CNRN8, CNRS8, CRNR8, PCDH-ALPHA10 ENSG00000250120 Protocadherin alpha 10 5 140855883-141012344 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced cerebral cortex: 17.5 thyroid gland: 4.3 Cell line enriched 10 EFO-21: 16.6 +ARPC4-TTLL3 ENSG00000250151 ARPC4-TTLL3 readthrough 3 9793082-9835401 Predicted intracellular proteins Evidence at transcript level Not detected Mixed bone marrow: 4.3 Mixed +PTTG2 ENSG00000250254 Pituitary tumor-transforming 2 4 37960435-37961125 Predicted intracellular proteins Evidence at transcript level HPA008890, HPA045034 Uncertain Approved Nucleoli
Cytosol Not detected Not detected bone marrow: 0.7 Not detected +XXbac-BPG246D15.9 ENSG00000250264 6 32813767-32838822 Predicted membrane proteins Evidence at transcript level HPA001312 Approved Approved Nuclear speckles
Endoplasmic reticulum Not detected Tissue enhanced appendix: 15.5;spleen: 9.5 lymph node: 6.5 Cell line enhanced Daudi: 14.2;HDLM-2: 12.4;HEL: 12.9 +GIMD1 ENSG00000250298 GIMAP family P-loop NTPase domain containing 1 4 106357485-106368825 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced duodenum: 28.6;small intestine: 18.0 gallbladder: 4.9 Not detected +KIAA1456 C8orf79, FLJ36980 ENSG00000250305 KIAA1456 8 12945642-13031503 Predicted intracellular proteins Evidence at transcript level HPA024673 Approved Approved Nucleus
Cytosol Renal cancer:2.77e-7 (favourable) Tissue enhanced Tissue enhanced thyroid gland: 31.4 cerebral cortex: 6.6 Cell line enhanced AF22: 6.3;BJ: 7.8;fHDF/TERT166: 9.6;SCLC-21H: 5.2 +ZNF718 FLJ90036 ENSG00000250312 Zinc finger protein 718 4 124480-163989 Predicted intracellular proteins Evidence at transcript level Renal cancer:7.67e-6 (favourable) Expressed in all Mixed thyroid gland: 8.7 Cell line enhanced REH: 18.4 +SMIM20 C4orf52 ENSG00000250317 Small integral membrane protein 20 4 25861830-25929874 Predicted membrane proteins Evidence at protein level HPA016552 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:8.97e-5 (favourable) Expressed in all Expressed in all epididymis: 88.0 Expressed in all +RP5-972B16.2 ENSG00000250349 X 37349330-38687674 Predicted membrane proteins Evidence at protein level HPA003140 Uncertain Not detected Not detected skeletal muscle: 0.9 Not detected +GYPB CD235b, GPB, MNS, SS ENSG00000250361 Glycophorin B (MNS blood group) 4 143996104-144019345 Blood group antigen proteins, CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 5 bone marrow: 37.2 placenta: 7.3 Cell line enriched 5 HEL: 225.3 +TUNAR HI-LNC78, LINC00617, TUNA ENSG00000250366 TCL1 upstream neural differentiation-associated RNA 14 95876392-95925571 Predicted membrane proteins Evidence at transcript level Renal cancer:1.55e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 4.0;endometrium: 1.8;fallopian tube: 2.5 seminal vesicle: 1.3 Cell line enhanced AF22: 3.2;NTERA-2: 6.8;SCLC-21H: 7.9 +TRIM75P TRIM75 ENSG00000250374 Tripartite motif containing 75, pseudogene 4 165059148-165060554 Predicted intracellular proteins Evidence at transcript level Tissue enriched Not detected placenta,testis: 0.2 Cell line enriched 17 BEWO: 2.0 +RP11-119J18.1 ENSG00000250378 5 135812667-135826584 Predicted intracellular proteins Evidence at transcript level Mixed Group enriched 12 skin: 2.1;testis: 4.6 breast,duodenum,esophagus,kidney: 0.2 Cell line enhanced HEL: 1.4;SK-MEL-30: 1.3 +KIAA1210 ENSG00000250423 KIAA1210 X 119078635-119150579 Predicted intracellular proteins Evidence at protein level HPA000551, HPA048322 Enhanced Tissue enhanced Group enriched 5 epididymis: 47.9;seminal vesicle: 27.4;testis: 58.3 fallopian tube: 8.6 Not detected +RP5-877J2.1 ENSG00000250424 7 30852273-30923812 Predicted membrane proteins Evidence at protein level HPA019206, HPA030130 Approved Approved Plasma membrane Not detected Tissue enhanced gallbladder: 1.5 fallopian tube: 1.2 Not detected +CHCHD10 C22orf16, N27C7-4 ENSG00000250479 Coiled-coil-helix-coiled-coil-helix domain containing 10 22 23765834-23768443 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003440 Enhanced Supported Mitochondria Renal cancer:2.15e-7 (favourable) Expressed in all Expressed in all skeletal muscle: 220.6 Mixed +FAM218A C4orf39, FLJ31659 ENSG00000250486 Family with sequence similarity 218 member A 4 164956948-164959122 Predicted intracellular proteins Evidence at protein level Mixed Mixed testis: 5.6 Cell line enhanced LHCN-M2: 1.8;SCLC-21H: 5.0 +CDK3 ENSG00000250506 Cyclin dependent kinase 3 17 76000906-76005999 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007420 Uncertain Approved Cytosol Mixed Mixed skin: 29.2 Expressed in all +GPR162 A-2, GRCA ENSG00000250510 G protein-coupled receptor 162 12 6821545-6829972 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055135 Enhanced Approved Microtubule organizing center Renal cancer:1.37e-6 (unfavourable), Pancreatic cancer:4.29e-5 (favourable) Tissue enriched Group enriched 6 cerebral cortex: 84.3;fallopian tube: 29.4 lung: 9.5 Cell line enhanced AF22: 17.4;AN3-CA: 19.5;NTERA-2: 19.7;SH-SY5Y: 14.2;U-2 OS: 17.2 +ATP6V1E2 ATP6E1, ATP6EL2, ATP6V1EL2, MGC9341, VMA4 ENSG00000250565 ATPase H+ transporting V1 subunit E2 2 46490750-46542557 Predicted intracellular proteins Evidence at protein level HPA052784 Uncertain Expressed in all Group enriched 6 epididymis: 7.7;testis: 31.6 cerebral cortex: 3.2 Mixed +GLI4 HKR4, ZNF928 ENSG00000250571 GLI family zinc finger 4 8 143267433-143276931 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023131 Uncertain Approved Nucleus
Cytokinetic bridge Expressed in all Expressed in all spleen: 8.8 Expressed in all +XXbac-BPG32J3.19 ENSG00000250641 6 31706904-31717918 Predicted membrane proteins No evidence HPA008053 Uncertain Tissue enriched Not detected testis: 0.5 Not detected +RP11-295K3.1 ENSG00000250644 11 1734821-1763954 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003001 Uncertain Mixed Tissue enhanced adrenal gland: 83.1 cerebral cortex: 29.6 Cell line enhanced CAPAN-2: 196.3;SH-SY5Y: 53.0;U-87 MG: 58.5 +RP11-6L6.2 ENSG00000250673 4 146214515-146230878 Predicted membrane proteins Evidence at transcript level Mixed Not detected skin: 0.4 Cell line enriched 89 HDLM-2: 8.9 +CCDC169-SOHLH2 C13orf38-SOHLH2 ENSG00000250709 CCDC169-SOHLH2 readthrough 13 36168794-36297842 Predicted intracellular proteins Evidence at transcript level HPA029182 Uncertain Vesicles Not detected Tissue enriched 28 testis: 19.5 seminal vesicle: 0.7 Cell line enhanced BEWO: 1.3;HL-60: 2.2;U-937: 1.7 +RP11-322N21.2 ENSG00000250719 Homo sapiens phosphoinositide-3-kinase regulatory subunit 3 (PIK3R3), transcript variant 13, mRNA. 1 46175486-46176478 Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level Not detected Tissue enriched 937 testis: 93.7 all non-specific tissues: 0.0 Not detected +SELENOP SELP, SeP, SEPP, SEPP1 ENSG00000250722 Selenoprotein P 5 42799880-42887392 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA036287 Approved Approved Nucleus
Golgi apparatus Renal cancer:6.97e-6 (favourable) Expressed in all Expressed in all liver: 2947.1 Cell line enhanced Hep G2: 350.2;HSkMC: 307.3;T-47d: 109.6 +NT5C1B-RDH14 ENSG00000250741 NT5C1B-RDH14 readthrough 2 18555545-18589564 Predicted intracellular proteins Evidence at transcript level HPA056683 Uncertain Not detected Tissue enriched 174 testis: 23.1 duodenum: 0.1 Not detected +USP17L20 ENSG00000250745 Ubiquitin specific peptidase 17-like family member 20 4 9258124-9260075 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +RP11-432M8.13 ENSG00000250782 5 17634460-17635053 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 11 U-2 OS: 1.0 +PRODH2 HSPOX1 ENSG00000250799 Proline dehydrogenase 2 19 35799988-35813299 Enzymes, Predicted intracellular proteins Evidence at protein level HPA051287 Approved Supported Nucleoplasm
Cytosol Group enriched Group enriched 96 kidney: 132.8;liver: 45.1 testis: 0.9 Cell line enriched 14 Hep G2: 21.4 +CTC-441N14.4 ENSG00000250803 Uncharacterized protein LOC100505841 5 122129622-122183949 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 19 testis: 53.8 fallopian tube: 2.8 Not detected +RP11-345F18.1 ENSG00000250821 4 55819819-55837487 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.3 Cell line enhanced HEK 293: 1.4 +USP17L18 ENSG00000250844 Ubiquitin specific peptidase 17-like family member 18 4 9248630-9250581 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +USP17L23 ENSG00000250913 Ubiquitin specific peptidase 17-like family member 23 4 9272364-9272914 Enzymes, Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +RP11-484M3.5 ENSG00000251012 3 119147375-119187807 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.2 Not detected +RP11-101E3.5 ENSG00000251184 9 128941478-128957021 Predicted intracellular proteins Evidence at transcript level Not detected Not detected endometrium,urinary bladder: 0.6 Cell line enhanced BJ: 1.6;HL-60: 1.4;RH-30: 1.8;U-138 MG: 1.4 +ZNF674 MRX92, ZNF673B ENSG00000251192 Zinc finger protein 674 X 46497727-46545457 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031026, HPA065295 Uncertain Mixed Mixed prostate: 3.3 Mixed +TMED7-TICAM2 ENSG00000251201 TMED7-TICAM2 readthrough 5 115578642-115626161 Predicted secreted proteins Evidence at protein level HPA008960 Uncertain Not detected Mixed placenta: 4.7 Mixed +RP11-540D14.8 ENSG00000251246 1 155063748-155086807 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 1.2 testis: 0.7 Cell line enhanced RPMI-8226: 2.2;U-266/70: 2.0 +ZNF345 HZF10 ENSG00000251247 Zinc finger protein 345 19 36850361-36913029 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA025816 Uncertain Mixed Mixed testis: 17.7 Mixed +RFPL4B RNF211 ENSG00000251258 Ret finger protein like 4B 6 112347330-112351296 Predicted intracellular proteins Evidence at transcript level HPA059324, HPA066464 Uncertain Group enriched Tissue enriched 5 testis: 2.9 placenta: 0.5 Cell line enhanced K-562: 1.7;RPTEC TERT1: 1.8;U-266/84: 5.6 +ALG1L2 ENSG00000251287 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase like 2 3 130081831-130113227 Predicted intracellular proteins Evidence at protein level HPA060392 Uncertain Uncertain Nucleoli fibrillar center
Endoplasmic reticulum Ovarian cancer:7.75e-4 (favourable) Mixed Tissue enhanced spleen: 1.0 appendix,duodenum,skin: 0.2 Not detected +SHANK3 KIAA1650, prosap2, PSAP2, SPANK-2 ENSG00000251322 SH3 and multiple ankyrin repeat domains 3 22 50674415-50733298 Predicted intracellular proteins Evidence at protein level HPA003446, CAB079070 Enhanced Approved Colorectal cancer:7.40e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 2.7 Cell line enhanced HEL: 3.8;TIME: 4.6 +MSANTD3-TMEFF1 C9orf30-TMEFF1 ENSG00000251349 MSANTD3-TMEFF1 readthrough 9 100442271-100577636 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 48.0 testis: 10.2 Cell line enhanced AF22: 98.5;NTERA-2: 50.5;SCLC-21H: 63.0 +AP000350.10 ENSG00000251357 22 23862188-23895223 Predicted membrane proteins Evidence at transcript level HPA042960 Uncertain Not detected Not detected adrenal gland: 0.5 Cell line enhanced SCLC-21H: 2.3 +ZNF550 MGC41917 ENSG00000251369 Zinc finger protein 550 19 57535257-57559863 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003251 Uncertain Approved Vesicles
Microtubules Prostate cancer:2.21e-4 (unfavourable) Expressed in all Mixed ovary: 12.7 Mixed +DCANP1 C5orf20, DCNP1 ENSG00000251380 Dendritic cell associated nuclear protein 5 135444214-135447348 Predicted intracellular proteins Evidence at protein level HPA048308 Uncertain Not detected Not detected lymph node: 0.7 Cell line enhanced THP-1: 1.3 +FOXD1 FKHL8, FREAC4 ENSG00000251493 Forkhead box D1 5 73444827-73448527 Predicted intracellular proteins, Transcription factors Evidence at protein level Head and neck cancer:2.73e-4 (unfavourable), Urothelial cancer:9.65e-4 (unfavourable) Mixed Tissue enhanced testis: 4.5 adrenal gland: 2.6 Cell line enhanced hTEC/SVTERT24-B: 60.8;U-138 MG: 79.5 +APITD1-CORT ENSG00000251503 APITD1-CORT readthrough 1 10430102-10452153 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 8 testis: 38.7 bone marrow: 5.0 Mixed +RP11-385D13.1 ENSG00000251537 17 15571491-15651653 Predicted intracellular proteins Evidence at protein level HPA023623, HPA066431 Uncertain Approved Plasma membrane
Cytosol Not detected Not detected skin: 0.4 Cell line enhanced A549: 1.2;CAPAN-2: 1.0;HaCaT: 2.2 +RP11-724O16.1 ENSG00000251569 2 169479480-169525922 Predicted intracellular proteins Evidence at transcript level HPA046125 Uncertain Not detected Tissue enhanced testis: 16.8 fallopian tube,thyroid gland: 3.8 Cell line enhanced ASC TERT1: 3.8;HSkMC: 2.9;LHCN-M2: 4.9 +PRB1 PM, PMF, PMS, PRB1L, PRB1M ENSG00000251655 Proline rich protein BstNI subfamily 1 12 11351823-11395566 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 4399 salivary gland: 6733.7 skin: 1.5 Not detected +PCDHA12 PCDH-ALPHA12 ENSG00000251664 Protocadherin alpha 12 5 140875302-141012344 Predicted membrane proteins Evidence at transcript level HPA035812 Approved Approved Cytosol Not detected Tissue enhanced lung: 2.7 cerebral cortex: 1.8 Cell line enhanced A549: 6.8;hTCEpi: 3.3;PC-3: 5.3;RT4: 4.6;SH-SY5Y: 3.3 +PTX4 C16orf38 ENSG00000251692 Pentraxin 4 16 1485886-1488981 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA064718, HPA073694 Uncertain Uncertain Cytosol Not detected Not detected testis: 0.8 Group enriched 6 HL-60: 16.9;NB-4: 9.9 +OC90 PLA2L ENSG00000253117 Otoconin 90 8 132024220-132059380 Predicted secreted proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +RGS21 ENSG00000253148 Regulator of G-protein signaling 21 1 192316992-192367285 Predicted intracellular proteins Evidence at transcript level HPA052843 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +PCDHGA12 CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12 ENSG00000253159 Protocadherin gamma subfamily A, 12 5 141430589-141512979 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Tissue enhanced Mixed cerebral cortex: 8.1 Cell line enhanced BJ: 8.3;BJ hTERT+: 13.2;fHDF/TERT166: 18.9;HSkMC: 12.6 +C8orf88 ENSG00000253250 Chromosome 8 open reading frame 88 8 90958637-90985257 Predicted intracellular proteins Evidence at protein level Urothelial cancer:6.23e-6 (unfavourable), Melanoma:4.90e-4 (unfavourable) Mixed Tissue enhanced testis: 183.0 smooth muscle: 46.1 Mixed +CTC-534A2.2 ENSG00000253251 5 65624765-65630891 Predicted intracellular proteins Evidence at protein level HPA066071, HPA068764 Approved Supported Nucleoplasm
Nucleoli Urothelial cancer:1.17e-4 (favourable) Expressed in all Mixed bone marrow: 10.0 Expressed in all +CCDC71L C7orf74, FLJ36031 ENSG00000253276 Coiled-coil domain containing 71-like 7 106656765-106660996 Predicted intracellular proteins Evidence at protein level HPA067925 Approved Approved Golgi apparatus
Actin filaments
Cytosol Renal cancer:2.53e-6 (unfavourable), Cervical cancer:9.08e-4 (unfavourable) Expressed in all Mixed adipose tissue: 31.1 Mixed +HOXA10 HOX1, HOX1H ENSG00000253293 Homeobox A10 7 27170591-27180261 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB019384 Approved Supported Nucleoplasm
Nuclear bodies Mixed Tissue enhanced endometrium: 116.6;smooth muscle: 67.6 prostate: 42.2 Cell line enhanced HEK 293: 164.0;U-937: 78.1 +TMEM200B TTMB ENSG00000253304 Transmembrane protein 200B 1 29119428-29123935 Predicted membrane proteins Evidence at transcript level HPA055254 Uncertain Mixed Tissue enhanced endometrium: 69.1 seminal vesicle: 54.2 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 28.3 +PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 Protocadherin gamma subfamily B, 6 5 141408021-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Mixed Tissue enhanced cerebral cortex: 20.8 parathyroid gland: 11.9 Cell line enhanced AF22: 15.8;EFO-21: 5.1 +SERPINE3 ENSG00000253309 Serpin family E member 3 13 51335773-51364735 Predicted secreted proteins Evidence at protein level HPA051904, HPA055804 Uncertain Not detected Tissue enhanced skin: 1.0 small intestine: 0.8 Not detected +C1orf210 MGC52423 ENSG00000253313 Chromosome 1 open reading frame 210 1 43281883-43285617 Predicted membrane proteins Evidence at protein level HPA013788 Uncertain Uncertain Nucleoli Renal cancer:0.00e+0 (favourable) Mixed Mixed duodenum: 44.3 Cell line enhanced A-431: 10.7;BEWO: 12.7;CACO-2: 10.5;CAPAN-2: 35.4;T-47d: 14.3 +TRNP1 C1orf225, LOC388610 ENSG00000253368 TMF1-regulated nuclear protein 1 1 26993707-27000898 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Liver cancer:1.90e-6 (unfavourable), Renal cancer:7.72e-4 (unfavourable) Expressed in all Tissue enhanced stomach: 116.8 esophagus: 49.6 Mixed +SMIM18 ENSG00000253457 Small integral membrane protein 18 8 30638600-30646064 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066648 Supported Uncertain Nucleus
Centrosome Tissue enriched Tissue enriched 9 cerebral cortex: 11.1 adrenal gland: 1.3 Cell line enriched 6 SH-SY5Y: 9.9 +PCDHGA5 CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5 ENSG00000253485 Protocadherin gamma subfamily A, 5 5 141364232-141512979 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Tissue enhanced Mixed cerebral cortex: 3.8 Group enriched 6 ASC diff: 10.8;ASC TERT1: 4.3 +NACA2 MGC71999, NACAL ENSG00000253506 Nascent polypeptide associated complex alpha subunit 2 17 61590426-61591202 Predicted intracellular proteins Evidence at protein level HPA073152, HPA073648 Approved Cytosol Mixed Tissue enriched 129 testis: 104.2 appendix,ovary: 0.8 Cell line enhanced NB-4: 2.1 +PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 Protocadherin gamma subfamily A, 7 5 141382739-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Mixed Tissue enhanced cerebral cortex: 7.4 thyroid gland: 3.3 Cell line enhanced BJ hTERT+: 17.1;SH-SY5Y: 19.7 +PYDC2 POP2 ENSG00000253548 Pyrin domain containing 2 3 191461163-191461456 Predicted intracellular proteins Evidence at protein level HPA055895 Uncertain Not detected Not detected all non-specific tissues: 0.0 Cell line enriched 10 A549: 1.0 +SLC10A5 ENSG00000253598 Solute carrier family 10 member 5 8 81693607-81696174 Predicted membrane proteins, Transporters Evidence at protein level HPA025966 Uncertain Approved Plasma membrane Mixed Mixed liver: 3.0 Not detected +EIF5AL1 bA342M3.3, EIF5AP1 ENSG00000253626 Eukaryotic translation initiation factor 5A-like 1 10 79512601-79516440 Predicted intracellular proteins, Transporters Evidence at transcript level Cervical cancer:4.23e-4 (favourable) Expressed in all Tissue enriched 13 testis: 19.8 parathyroid gland: 1.5 Mixed +PRSS51 ENSG00000253649 Protease, serine 51 8 10482878-10547585 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Mixed Tissue enhanced breast: 1.0;testis: 1.1 cerebral cortex: 0.5 Cell line enhanced U-2 OS: 1.4 +ALG11 CDG1P, KIAA0266 ENSG00000253710 ALG11, alpha-1,2-mannosyltransferase 13 52012398-52029664 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047214 Approved Mixed Expressed in all thyroid gland: 23.6 Expressed in all +ATXN7L3B lnc-SCA7 ENSG00000253719 Ataxin 7 like 3B 12 74537827-74545430 Predicted intracellular proteins Evidence at protein level HPA056612 Approved Nucleoplasm Renal cancer:2.25e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 61.5 Expressed in all +PRKDC DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7 ENSG00000253729 Protein kinase, DNA-activated, catalytic polypeptide 8 47773108-47960183 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005167, HPA035174 Supported Enhanced Nucleoplasm Endometrial cancer:1.03e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.6 Expressed in all +PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 Protocadherin gamma subfamily A, 6 5 141373914-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Mixed Mixed endometrium,ovary: 3.8 Cell line enhanced SCLC-21H: 11.4;WM-115: 12.0 +PCDHGA8 KIAA0327, PCDH-GAMMA-A8 ENSG00000253767 Protocadherin gamma subfamily A, 8 5 141390157-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Not detected Not detected thyroid gland: 0.7 Not detected +UTP14C 2700066J21Rik, KIAA0266 ENSG00000253797 UTP14, small subunit processome component homolog C (S. cerevisiae) 13 52024691-52033600 Predicted intracellular proteins Evidence at protein level HPA047217, HPA054023 Uncertain Approved Nucleoli
Cytosol Renal cancer:1.46e-5 (favourable), Ovarian cancer:7.52e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.6 Expressed in all +ETV3L FLJ16478 ENSG00000253831 ETS variant 3 like 1 157092044-157099808 Predicted intracellular proteins, Transcription factors Evidence at transcript level Not detected Not detected breast: 0.9 Cell line enriched 16 HDLM-2: 32.0 +PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 Protocadherin gamma subfamily A, 10 5 141412987-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Mixed Tissue enriched 5 cerebral cortex: 28.0 placenta: 5.1 Cell line enhanced AF22: 14.4;T-47d: 18.5 +PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 Protocadherin gamma subfamily A, 11 5 141421047-141512979 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Mixed Mixed cerebral cortex,placenta: 3.2 Cell line enhanced ASC diff: 16.8;ASC TERT1: 18.5;SK-MEL-30: 16.7;WM-115: 43.4 +PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 Protocadherin gamma subfamily B, 2 5 141360042-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580, HPA077526 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Tissue enriched Mixed cerebral cortex: 6.5 Cell line enhanced ASC diff: 9.2 +PCDHGB4 CDH20, FIB2, PCDH-GAMMA-B4 ENSG00000253953 Protocadherin gamma subfamily B, 4 5 141387698-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Mixed Mixed placenta: 4.3 Cell line enhanced BJ hTERT+: 35.5;TIME: 18.0 +CLDN23 CLDNL ENSG00000253958 Claudin 23 8 8701938-8704106 Predicted membrane proteins, Transporters Evidence at protein level HPA070578 Uncertain Nucleus
Plasma membrane Renal cancer:9.65e-8 (favourable), Colorectal cancer:3.46e-4 (favourable) Expressed in all Tissue enhanced colon: 23.7;stomach: 24.5 small intestine: 16.5 Cell line enhanced BEWO: 7.4 +ZNF260 ozrf1, Zfp260 ENSG00000254004 Zinc finger protein 260 19 36510695-36528660 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028806 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.44e-4 (favourable) Expressed in all Mixed parathyroid gland: 20.5 Mixed +LYN JTK8 ENSG00000254087 LYN proto-oncogene, Src family tyrosine kinase 8 55879813-56014168 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001231, CAB004492 Enhanced Supported Golgi apparatus
Vesicles
Plasma membrane Renal cancer:3.43e-4 (unfavourable) Expressed in all Tissue enhanced spleen: 161.1 appendix: 130.6 Cell line enhanced HEL: 215.0;HMC-1: 205.1 +PINX1 FLJ20565, LPTL, LPTS, MGC8850, PinX1 ENSG00000254093 PIN2/TERF1 interacting, telomerase inhibitor 1 8 10764963-10839884 Predicted intracellular proteins Evidence at protein level HPA023139 Uncertain Cervical cancer:2.45e-5 (favourable) Expressed in all Expressed in all testis: 16.1 Expressed in all +PCDHGB7 ME6, PCDH-GAMMA-B7 ENSG00000254122 Protocadherin gamma subfamily B, 7 5 141417645-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Tissue enhanced Mixed ovary: 10.2 Cell line enhanced AN3-CA: 80.7;HSkMC: 19.4 +NPIPB11 ENSG00000254206 Nuclear pore complex interacting protein family member B11 16 29381354-29404029 Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Mixed Mixed skin: 8.1 Mixed +PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 Protocadherin gamma subfamily B, 1 5 141350102-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580, HPA076182 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Focal adhesion sites
Midbody
Cytosol Mixed Tissue enriched 11 cerebral cortex: 23.8 endometrium: 2.0 Cell line enhanced ASC diff: 8.8;T-47d: 8.1 +PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 Protocadherin gamma subfamily A, 3 5 141343829-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Not detected Tissue enhanced cerebral cortex: 6.5 ovary: 3.1 Group enriched 7 AF22: 7.0;BJ: 2.0;EFO-21: 5.4 +LRRC24 LRRC14OS ENSG00000254402 Leucine rich repeat containing 24 8 144522377-144527032 Predicted membrane proteins Evidence at protein level HPA028171, HPA052250 Enhanced Approved Vesicles Not detected Tissue enhanced parathyroid gland: 3.6;prostate: 4.5 cerebral cortex: 3.1 Cell line enhanced SCLC-21H: 3.2;SH-SY5Y: 7.9 +SIGLEC14 ENSG00000254415 Sialic acid binding Ig like lectin 14 19 51642553-51646801 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA014377 Uncertain Mixed Tissue enhanced appendix: 34.8;spleen: 55.2 bone marrow: 18.3 Group enriched 10 HMC-1: 87.0;U-937: 19.3 +PBOV1 UC28, UROC28 ENSG00000254440 Prostate and breast cancer overexpressed 1 6 138215986-138218491 Predicted intracellular proteins Evidence at transcript level HPA063021 Uncertain Not detected Not detected bone marrow,kidney,parathyroid gland,skin: 0.1 Not detected +OR4D10 OR4D10P, OST711 ENSG00000254466 Olfactory receptor family 4 subfamily D member 10 11 59477373-59478396 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Tissue enriched Not detected all non-specific tissues: 0.0 Not detected +RP11-849H4.2 ENSG00000254469 Putative short transient receptor potential channel 2-like protein 11 71865509-71928654 Predicted intracellular proteins Evidence at protein level HPA051121, HPA058841 Uncertain Supported Nucleoli Mixed Mixed epididymis: 7.0 Expressed in all +AP5B1 AP-5, DKFZp761E198, PP1030 ENSG00000254470 Adaptor related protein complex 5 beta 1 subunit 11 65775893-65780802 Predicted intracellular proteins Evidence at protein level HPA065739, HPA067880 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Renal cancer:2.31e-5 (favourable) Expressed in all Expressed in all bone marrow: 25.1 Mixed +CHMP4A C14orf123, HSPC134, VPS32A ENSG00000254505 Charged multivesicular body protein 4A 14 24209583-24213869 Predicted intracellular proteins Evidence at protein level HPA068473 Approved Renal cancer:3.91e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 130.5 Expressed in all +SIGLEC12 S2V, Siglec-12, Siglec-L1, Siglec-XII, SIGLECL1, SLG ENSG00000254521 Sialic acid binding Ig like lectin 12 (gene/pseudogene) 19 51491357-51501789 Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced appendix: 6.4;spleen: 12.8 smooth muscle: 3.7 Group enriched 9 HMC-1: 124.2;U-937: 61.4 +PABPC4L ENSG00000254535 Poly(A) binding protein cytoplasmic 4 like 4 134196333-134201748 Predicted intracellular proteins Evidence at protein level Renal cancer:1.11e-5 (favourable) Mixed Tissue enhanced parathyroid gland: 12.8;placenta: 14.7 endometrium: 6.4 Cell line enhanced HAP1: 11.9;HeLa: 10.3;REH: 7.4;RH-30: 8.3;U-2 OS: 9.1 +RP11-108K14.8 ENSG00000254536 10 133390834-133420495 Predicted intracellular proteins Evidence at protein level HPA037826, HPA037827 Uncertain Approved Mitochondria Not detected Tissue enhanced testis: 2.5 duodenum: 1.3 Cell line enhanced Karpas-707: 17.8;U-266/70: 4.0 +OMP ENSG00000254550 Olfactory marker protein 11 77102840-77103331 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced duodenum: 2.7;small intestine: 2.8 rectum: 2.0 Not detected +MAGEL2 NDNL1, nM15 ENSG00000254585 MAGE family member L2 15 23643544-23647841 Disease related genes, Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enhanced cerebral cortex: 3.3 cervix, uterine: 2.9 Group enriched 6 AF22: 3.2;NTERA-2: 1.9;U-2 OS: 1.0 +CSNK2A3 CSNK2A1P ENSG00000254598 Casein kinase 2 alpha 3 11 11351942-11353357 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059206, HPA061698 Uncertain Approved Nucleoplasm Mixed Not detected testis: 0.5 Cell line enhanced A-431: 2.1 +ARMS2 ARMD8, LOC387715 ENSG00000254636 Age-related maculopathy susceptibility 2 10 122454653-122457352 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA067225 Enhanced Not detected Tissue enhanced placenta: 2.0;testis: 2.9 ovary: 0.9 Not detected +INS IDDM1, IDDM2 ENSG00000254647 Insulin 11 2159779-2161341 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB000048, HPA004932, CAB012098, CAB053843 Enhanced Tissue enriched Tissue enriched 27 pancreas: 1850.7 skin: 68.2 Group enriched 10 EFO-21: 194.7;U-2 OS: 281.2;U-698: 61.2 +RTL1 Mar1, MART1, PEG11 ENSG00000254656 Retrotransposon-like 1 14 100880655-100884847 Predicted membrane proteins Evidence at protein level HPA066979 Approved Cytosol Tissue enhanced Group enriched 9 adrenal gland: 2.4;placenta: 4.5 cerebral cortex,testis: 0.3 Cell line enriched 35 SH-SY5Y: 664.4 +FPGT GFPP ENSG00000254685 Fucose-1-phosphate guanylyltransferase 1 74198212-74234086 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA072331 Uncertain Vesicles Liver cancer:2.30e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 32.8 Expressed in all +RP11-468E2.1 ENSG00000254692 14 24189157-24213473 Predicted membrane proteins Evidence at protein level HPA059249 Approved Approved Golgi apparatus Not detected Expressed in all parathyroid gland: 54.2 Mixed +RP11-565P22.6 ENSG00000254706 1 162365407-162383531 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced seminal vesicle: 4.2 gallbladder: 2.3 Cell line enhanced HEL: 6.5 +IGLL5 ENSG00000254709 Immunoglobulin lambda like polypeptide 5 22 22887780-22896107 Predicted intracellular proteins Evidence at protein level Renal cancer:5.94e-8 (unfavourable), Head and neck cancer:3.41e-5 (favourable), Breast cancer:6.10e-4 (favourable) Expressed in all Tissue enhanced tonsil: 836.2 urinary bladder: 638.6 Group enriched 7 Daudi: 472.9;U-266/70: 346.8;U-698: 308.3 +MEX3A RKHD4 ENSG00000254726 Mex-3 RNA binding family member A 1 156072013-156081998 Predicted intracellular proteins Evidence at protein level HPA062703 Supported Cytosol Liver cancer:9.23e-8 (unfavourable) Expressed in all Tissue enhanced endometrium: 5.9;ovary: 5.9 cerebral cortex: 4.1 Cell line enhanced AF22: 63.9;NTERA-2: 58.9;SCLC-21H: 71.7;SH-SY5Y: 117.8 +OR10G4 ENSG00000254737 Olfactory receptor family 10 subfamily G member 4 11 124015575-124016510 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected pancreas,rectum: 0.1 Not detected +EEF1G EF1G ENSG00000254772 Eukaryotic translation elongation factor 1 gamma 11 62559601-62574086 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040688, HPA055316 Enhanced Approved Mitochondria Mixed Expressed in all ovary: 2996.8 Expressed in all +CKLF-CMTM1 ENSG00000254788 CKLF-CMTM1 readthrough 16 66552587-66579135 Predicted membrane proteins Evidence at transcript level HPA017136 Approved Mixed Mixed testis: 4.0 Mixed +SLC22A18AS BWR1B, BWSCR1B, ORCTL2S, p27-BWR1B, SLC22A1LS ENSG00000254827 Solute carrier family 22 member 18 antisense 11 2887780-2903740 Predicted intracellular proteins Evidence at protein level HPA068288 Enhanced Supported Nucleoplasm Mixed Tissue enhanced colon: 14.4;duodenum: 13.5 small intestine: 11.0 Cell line enhanced A549: 8.7;CAPAN-2: 8.3;MCF7: 14.0;SK-MEL-30: 26.1;WM-115: 14.7 +OR5M10 ENSG00000254834 Olfactory receptor family 5 subfamily M member 10 11 56576774-56577721 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +NPIPA2 ENSG00000254852 Nuclear pore complex interacting protein family member A2 16 14748066-14765413 Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Not detected Tissue enhanced testis: 3.6 cerebral cortex: 1.8 Cell line enhanced BEWO: 6.5 +MPV17L2 FKSG24, MGC12972 ENSG00000254858 MPV17 mitochondrial inner membrane protein like 2 19 18193182-18196948 Predicted membrane proteins Evidence at protein level HPA043111 Uncertain Approved Plasma membrane
Cytosol Renal cancer:2.30e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 16.3 Expressed in all +AC113404.1 ENSG00000254893 Ras-related protein Rap-1b-like protein 5 76170093-76174331 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enriched 8 small intestine: 3.4 adrenal gland: 0.4 Group enriched 8 Daudi: 7.6;Karpas-707: 13.3;RPMI-8226: 11.1 +BORCS8 MEF2BNB ENSG00000254901 BLOC-1 related complex subunit 8 19 19176903-19192591 Predicted intracellular proteins Evidence at protein level HPA045700 Approved Approved Nucleoplasm
Vesicles Pancreatic cancer:4.05e-5 (favourable) Expressed in all Mixed cerebral cortex: 17.3 Expressed in all +RP11-872D17.8 ENSG00000254979 11 57387365-57424059 Predicted membrane proteins Evidence at protein level HPA038515 Supported Mixed Tissue enhanced bone marrow: 7.7;placenta: 10.5 skin: 5.8 Cell line enriched 7 HMC-1: 162.8 +DPP3 ENSG00000254986 Dipeptidyl peptidase 3 11 66480013-66509657 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035780, HPA035781 Approved Enhanced Nuclear speckles
Plasma membrane
Cytosol Stomach cancer:1.34e-4 (favourable) Expressed in all Expressed in all colon: 29.7 Expressed in all +ANKHD1-EIF4EBP3 MASK-BP3 ENSG00000254996 ANKHD1-EIF4EBP3 readthrough 5 140401908-140549569 Predicted intracellular proteins Evidence at transcript level HPA008718 Approved Mixed Expressed in all parathyroid gland: 40.5 Expressed in all +KRTAP5-9 KRN1, KRTAP5-1, KRTAP5.9 ENSG00000254997 Keratin associated protein 5-9 11 71548418-71549553 Predicted intracellular proteins Evidence at protein level Urothelial cancer:9.25e-4 (favourable) Tissue enhanced Tissue enhanced testis: 2.6 epididymis: 1.8 Cell line enriched 22 RT4: 7.2 +BRK1 C3orf10, HSPC300, MDS027 ENSG00000254999 BRICK1, SCAR/WAVE actin nucleating complex subunit 3 10115592-10127190 Predicted intracellular proteins Evidence at protein level HPA060391 Approved Nuclear speckles
Cell Junctions Liver cancer:5.76e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 225.0 Expressed in all +UBTFL1 C11orf27 ENSG00000255009 Upstream binding transcription factor, RNA polymerase I-like 1 11 90085950-90087131 Predicted intracellular proteins, Transcription factors No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +OR5M1 OST050 ENSG00000255012 Olfactory receptor family 5 subfamily M member 1 11 56612555-56613502 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +SAA2-SAA4 ENSG00000255071 SAA2-SAA4 readthrough 11 18231423-18248635 Predicted membrane proteins Evidence at transcript level HPA060139 Uncertain Renal cancer:2.92e-8 (unfavourable), Breast cancer:4.56e-4 (favourable), Glioma:9.87e-4 (unfavourable) Tissue enriched Tissue enhanced adipose tissue: 27.9;cervix, uterine: 22.6;liver: 15.0 breast: 5.4 Cell line enhanced A-431: 2.3;EFO-21: 1.4 +PIGY MGC14156 ENSG00000255072 Phosphatidylinositol glycan anchor biosynthesis class Y 4 88521573-88521789 Disease related genes, Predicted membrane proteins Evidence at protein level HPA059018 Uncertain Not detected Tissue enriched 11 colon: 1.0 all non-specific tissues: 0.0 Group enriched 10 AF22: 7.5;hTEC/SVTERT24-B: 10.7;MOLT-4: 13.8 +CHMP1B C18orf2, CHMP1.5, Vps46B ENSG00000255112 Charged multivesicular body protein 1B 18 11851396-11854449 Predicted intracellular proteins Evidence at protein level HPA061997, HPA062896 Enhanced Supported Nucleus
Midbody Renal cancer:7.37e-8 (favourable) Expressed in all Expressed in all thyroid gland: 87.0 Expressed in all +EID3 FLJ25832, NSE4B, NSMCE4B ENSG00000255150 EP300 interacting inhibitor of differentiation 3 12 104303739-104305205 Predicted intracellular proteins Evidence at protein level HPA059367 Uncertain Supported Nucleus
Nucleoli Renal cancer:5.96e-5 (unfavourable), Glioma:9.70e-5 (unfavourable) Mixed Tissue enriched 14 testis: 111.8 seminal vesicle: 7.7 Cell line enhanced A549: 8.2;BJ: 7.2 +GLYATL1P3 ENSG00000255151 Glycine-N-acyltransferase like 1 pseudogene 3 11 59086307-59094786 Predicted intracellular proteins Evidence at protein level HPA039501 Uncertain Uncertain Golgi apparatus
Cytosol Tissue enhanced Group enriched 6 breast: 9.7;lymph node: 3.4 appendix,prostate: 1.1 Cell line enhanced Daudi: 1.3;T-47d: 1.1;U-266/70: 1.4 +RP11-80H18.3 ENSG00000255154 Hydroxyacyl-thioester dehydratase type 2, mitochondrial 3 58306262-58318574 Predicted intracellular proteins Evidence at protein level HPA066812 Supported Nucleoli
Mitochondria Not detected Expressed in all thyroid gland: 14.6 Expressed in all +CCDC166 ENSG00000255181 Coiled-coil domain containing 166 8 143706694-143708109 Predicted intracellular proteins No evidence HPA025058 Uncertain Not detected Not detected testis: 0.5 Not detected +NANOGP8 ENSG00000255192 Nanog homeobox pseudogene 8 15 35084193-35085110 Predicted intracellular proteins Evidence at transcript level Tissue enriched Not detected testis: 0.8 Cell line enriched 125 NTERA-2: 50.8 +CARD17 INCA ENSG00000255221 Caspase recruitment domain family member 17 11 105092469-105101431 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enhanced skin: 3.5 lymph node: 1.9 Cell line enriched 5 AN3-CA: 1.4 +OR5M11 OR11-199 ENSG00000255223 Olfactory receptor family 5 subfamily M member 11 11 56542340-56543257 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.1 Not detected +FXYD6-FXYD2 ENSG00000255245 FXYD6-FXYD2 readthrough 11 117820163-117876667 Predicted membrane proteins Evidence at transcript level HPA068838, HPA075209 Approved Approved Nuclear membrane
Vesicles Not detected Tissue enhanced kidney: 5.6 salivary gland: 2.1 Group enriched 6 MOLT-4: 5.2;RPTEC TERT1: 5.3 +PRR23D1 ENSG00000255251 Proline rich 23 domain containing 1 8 7539628-7542450 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 54 epididymis: 75.6 testis: 1.3 Not detected +TMPRSS4-AS1 ENSG00000255274 TMPRSS4 antisense RNA 1 11 118003634-118088299 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced kidney: 1.2 lymph node,spleen: 0.8 Cell line enhanced Karpas-707: 7.8;RPMI-8226: 4.9;SCLC-21H: 1.7 +SDHD cybS, PGL, PGL1 ENSG00000255292 Succinate dehydrogenase complex subunit D 11 112086824-112193805 Disease related genes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA045727 Uncertain Not detected Tissue enriched 13 colon: 7.8 parathyroid gland: 0.5 Cell line enhanced A549: 23.8;CACO-2: 57.0;Hep G2: 19.6;hTEC/SVTERT24-B: 20.1;RT4: 30.5 +OR8G5 OR8G5P, OR8G6 ENSG00000255298 Olfactory receptor family 8 subfamily G member 5 11 124264827-124265867 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 31 testis: 6.2 placenta: 0.2 Cell line enhanced K-562: 2.3;PC-3: 1.1;T-47d: 1.9 +EID1 C15orf3, CRI1, EID-1 ENSG00000255302 EP300 interacting inhibitor of differentiation 1 15 48877886-48880183 Predicted intracellular proteins Evidence at protein level HPA051122, HPA051123 Approved Supported Nucleoplasm Stomach cancer:2.91e-4 (unfavourable), Head and neck cancer:9.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 315.2 Mixed +OR52B2 ENSG00000255307 Olfactory receptor family 52 subfamily B member 2 11 6169330-6170408 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +NOX5 NOX5A, NOX5B ENSG00000255346 NADPH oxidase 5 15 68930525-69062743 Predicted membrane proteins, Transporters Evidence at protein level Not detected Tissue enhanced spleen: 13.2 testis: 3.5 Not detected +CCDC179 ENSG00000255359 Coiled-coil domain containing 179 11 22846931-22860426 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 412 testis: 46.2 urinary bladder: 0.1 Not detected +TAS2R43 T2R52 ENSG00000255374 Taste 2 receptor member 43 12 11091287-11092313 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +PRR23D2 ENSG00000255378 Proline rich 23 domain containing 2 8 7778591-7781413 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 54 epididymis: 75.6 testis: 1.3 Not detected +HCAR3 GPR109B, HCA3, HM74 ENSG00000255398 Hydroxycarboxylic acid receptor 3 12 122714756-122716892 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA028660 Approved Approved Cell Junctions Mixed Tissue enhanced bone marrow: 16.6;spleen: 21.7 appendix: 12.4 Group enriched 6 HaCaT: 8.1;RT4: 28.3 +PCDHA3 PCDH-ALPHA3 ENSG00000255408 Protocadherin alpha 3 5 140801028-141012344 Predicted membrane proteins Evidence at transcript level HPA035667 Uncertain Not detected Mixed endometrium: 2.5 Cell line enhanced T-47d: 8.9;WM-115: 2.4 +EBLN2 ENSG00000255423 Endogenous Bornavirus-like nucleoprotein 2 3 73061659-73063337 Predicted intracellular proteins Evidence at protein level HPA062510, HPA068795 Uncertain Approved Nucleoplasm
Nuclear bodies Mixed Mixed bone marrow: 10.2 Mixed +RP11-831H9.11 ENSG00000255432 11 62649694-62665178 Predicted intracellular proteins No evidence Not detected Not detected cerebral cortex: 0.5 Not detected +RP11-196G11.1 ENSG00000255439 16 31083439-31094956 Predicted secreted proteins Evidence at transcript level HPA042720 Uncertain Approved Endoplasmic reticulum Not detected Not detected skin: 0.5 Mixed +CARD18 ICEBERG, pseudo-ICE, UNQ5804 ENSG00000255501 Caspase recruitment domain family member 18 11 105137721-105139726 Predicted intracellular proteins Evidence at protein level HPA038582 Approved Tissue enhanced Group enriched 7 breast: 10.6;skin: 29.7 esophagus: 3.0 Cell line enhanced BEWO: 3.0;hTCEpi: 1.9;U-2 OS: 2.9 +NPIPB8 ENSG00000255524 Nuclear pore complex interacting protein family member B8 16 28637654-28658682 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011188, HPA053611 Uncertain Approved Nucleoplasm Not detected Tissue enriched 12 testis: 12.8 small intestine: 1.1 Cell line enriched 23 hTCEpi: 15.2 +NEDD8-MDP1 ENSG00000255526 NEDD8-MDP1 readthrough 14 24213955-24232352 Predicted intracellular proteins Evidence at protein level HPA003064, HPA060254 Uncertain Approved Nucleoplasm Not detected Tissue enhanced parathyroid gland: 2.7 testis: 1.8 Cell line enhanced MOLT-4: 6.6 +POLR2M GCOM1, Gdown, Gdown1, GRINL1A ENSG00000255529 RNA polymerase II subunit M 15 57706629-57782762 Predicted intracellular proteins Evidence at protein level HPA068141 Approved Nucleoplasm Expressed in all Expressed in all endometrium: 59.9 Expressed in all +LY6G6E C6orf22, G6e ENSG00000255552 Lymphocyte antigen 6 family member G6E 6 31711771-31714065 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA056234 Approved Nucleus Not detected Tissue enhanced skin: 1.2;thyroid gland: 1.0 bone marrow: 0.8 Cell line enriched 103 HEL: 21.3 +FDXACB1 hCG_2033039, LOC91893 ENSG00000255561 Ferredoxin-fold anticodon binding domain containing 1 11 111874056-111881243 Predicted intracellular proteins Evidence at protein level HPA039012, HPA061375 Uncertain Uncertain Nucleus
Cytosol Expressed in all Mixed testis: 6.8 Mixed +OR10G2 ENSG00000255582 Olfactory receptor family 10 subfamily G member 2 14 21633836-21634940 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected lymph node: 0.2 Not detected +RAB44 dJ431A14.3, RASD3, RASL13 ENSG00000255587 RAB44, member RAS oncogene family 6 36697851-36733183 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 28 bone marrow: 38.8 gallbladder,lung: 1.3 Group enriched 204 HEL: 19.9;HL-60: 24.8;HMC-1: 79.3;NB-4: 50.2;THP-1: 20.3;U-937: 48.2 +RP4-809F18.1 ENSG00000255595 12 126191263-126361065 Predicted intracellular proteins No evidence Not detected Not detected cerebral cortex,gallbladder,pancreas,salivary gland: 0.1 Not detected +RP11-277P12.6 ENSG00000255641 12 10412312-10436001 Predicted membrane proteins Evidence at transcript level HPA062570 Uncertain Not detected Group enriched 7 cerebral cortex: 8.2;spleen: 6.1 bone marrow: 1.0 Cell line enriched 5 HeLa: 5.8 +TRIL KIAA0644 ENSG00000255690 TLR4 interactor with leucine rich repeats 7 28953358-28958292 Predicted membrane proteins Evidence at protein level Endometrial cancer:3.23e-4 (unfavourable), Ovarian cancer:8.52e-4 (unfavourable) Tissue enhanced Tissue enhanced cerebral cortex: 24.9 kidney: 5.7 Cell line enhanced AF22: 22.0;SH-SY5Y: 42.6;SK-BR-3: 26.9;T-47d: 14.9 +OR4D2 ENSG00000255713 Olfactory receptor family 4 subfamily D member 2 17 58169656-58170579 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +CTC-435M10.3 ENSG00000255730 19 41350853-41425001 Predicted intracellular proteins Evidence at protein level HPA036640 Approved Not detected Mixed cerebral cortex: 9.1 Cell line enhanced THP-1: 9.6 +RP13-512J5.1 ENSG00000255767 2 3531984-3547957 Predicted intracellular proteins Evidence at transcript level Not detected Mixed smooth muscle: 24.1 Mixed +OR6J1 OR6J1P, OR6J2 ENSG00000255804 Olfactory receptor family 6 subfamily J member 1 (gene/pseudogene) 14 22633768-22634811 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +MTRNR2L8 ENSG00000255823 MT-RNR2-like 8 11 10507887-10509189 Predicted intracellular proteins Evidence at transcript level Mixed Expressed in all heart muscle: 2071.6 Expressed in all +TIFAB ENSG00000255833 TIFA inhibitor 5 135444218-135452399 Predicted intracellular proteins Evidence at protein level HPA049372 Uncertain Tissue enhanced Tissue enhanced appendix: 4.9;lymph node: 6.3 tonsil: 4.5 Group enriched 14 THP-1: 6.0;U-937: 1.5 +RP4-559A3.7 ENSG00000255835 1 225886696-225924278 Predicted intracellular proteins No evidence Not detected Not detected cerebral cortex: 0.1 Not detected +TAS2R20 T2R20, T2R56, TAS2R49 ENSG00000255837 Taste 2 receptor member 20 12 10996495-10997875 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Mixed Not detected skin: 0.8 Not detected +KDM4F JMJD2F ENSG00000255855 Lysine demethylase 4F 11 95049422-95051338 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +AC073610.5 ENSG00000255863 12 48921963-48939663 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +CYP2A6 CPA6, CYP2A, CYP2A3 ENSG00000255974 Cytochrome P450 family 2 subfamily A member 6 19 40843538-40850447 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA046713, HPA047262 Supported Liver cancer:5.38e-5 (favourable) Tissue enriched Tissue enriched 67 liver: 839.4 breast: 12.4 Cell line enhanced RH-30: 1.1 +CTSO CTSO1 ENSG00000256043 Cathepsin O 4 155924118-155953917 Enzymes, Predicted secreted proteins Evidence at protein level HPA002041 Approved Expressed in all Expressed in all gallbladder: 32.4 Cell line enhanced HSkMC: 15.9;Karpas-707: 30.6 +MTRNR2L10 ENSG00000256045 MT-RNR2-like 10 X 55181391-55182920 Predicted intracellular proteins Evidence at transcript level Mixed Mixed kidney: 69.1 Cell line enhanced A549: 99.9;HeLa: 270.2;Hep G2: 240.3 +APOPT1 APOP-1, C14orf153, MGC2562 ENSG00000256053 Apoptogenic 1, mitochondrial 14 103562962-103607523 Predicted intracellular proteins Evidence at transcript level Liver cancer:6.34e-5 (unfavourable), Ovarian cancer:4.78e-4 (favourable) Expressed in all Expressed in all testis: 89.8 Expressed in all +TRAPPC2B MIP-2A, SEDLP, SEDLP1, TRAPPC2P1 ENSG00000256060 Trafficking protein particle complex 2B 19 57363511-57365353 Predicted intracellular proteins Evidence at protein level HPA063308 Approved Nucleoplasm
Endoplasmic reticulum
Vesicles Renal cancer:1.28e-4 (favourable) Expressed in all Expressed in all testis: 28.8 Mixed +DYX1C1 CILD25, DNAAF4, EKN1, FLJ37882 ENSG00000256061 Dyslexia susceptibility 1 candidate 1 15 55410525-55508234 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051048 Uncertain Approved Plasma membrane
Cytosol Mixed Tissue enhanced testis: 20.5 fallopian tube: 17.6 Mixed +ZNF432 KIAA0798 ENSG00000256087 Zinc finger protein 432 19 52031379-52095738 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052082, HPA060274, HPA065606 Uncertain Supported Nucleoplasm Urothelial cancer:4.11e-5 (favourable), Renal cancer:6.47e-4 (unfavourable) Expressed in all Expressed in all prostate: 21.1 Mixed +AP000721.4 ENSG00000256100 11 63974620-63988346 Predicted secreted proteins No evidence HPA055942 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +SMLR1 ENSG00000256162 Small leucine rich protein 1 6 130827406-130837135 Predicted membrane proteins Evidence at protein level HPA066060 Uncertain Tissue enriched Group enriched 5 duodenum: 12.2;liver: 28.9;small intestine: 11.4 kidney: 3.2 Cell line enriched 10 Hep G2: 55.1 +TAS2R30 T2R30, TAS2R47 ENSG00000256188 Taste 2 receptor member 30 12 11132958-11134644 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected endometrium,ovary,parathyroid gland,testis,thyroid gland: 0.2 Not detected +MTRNR2L3 ENSG00000256222 MT-RNR2-like 3 20 57358442-57359980 Predicted intracellular proteins Evidence at transcript level Not detected Not detected bone marrow,skeletal muscle,testis: 0.2 Not detected +ZNF10 KOX1 ENSG00000256223 Zinc finger protein 10 12 133130575-133159465 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003204 Uncertain Approved Nucleus
Vesicles
Plasma membrane Expressed in all Expressed in all parathyroid gland: 40.9 Mixed +ZNF486 KRBO2, MGC2396 ENSG00000256229 Zinc finger protein 486 19 20167228-20200490 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced thyroid gland: 63.5 urinary bladder: 17.2 Cell line enhanced HBF TERT88: 23.4 +SMIM3 C5orf62, MSTP150, NID67 ENSG00000256235 Small integral membrane protein 3 5 150777946-150796734 Predicted membrane proteins Evidence at protein level HPA075345 Approved Vesicles Renal cancer:1.15e-8 (unfavourable) Expressed in all Expressed in all adipose tissue: 109.0 Cell line enhanced ASC diff: 172.4;U-87 MG: 184.9 +HMBS PBGD, PORC, UPS ENSG00000256269 Hydroxymethylbilane synthase 11 119084866-119093549 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006114, HPA050659 Enhanced Approved Lipid droplets Expressed in all Tissue enriched 5 bone marrow: 52.8 parathyroid gland: 9.8 Expressed in all +ZNF225 ENSG00000256294 Zinc finger protein 225 19 44112181-44134816 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA073778 Approved Nucleoplasm Mixed Tissue enhanced testis: 22.8 breast: 10.6 Mixed +CTD-3074O7.11 ENSG00000256349 11 66509079-66533613 Predicted intracellular proteins Evidence at protein level HPA058283 Uncertain Uncertain Midbody Not detected Not detected lymph node: 0.3 Cell line enriched 6 NTERA-2: 11.7 +PPIAL4D ENSG00000256374 Peptidylprolyl isomerase A like 4D 1 145241630-145242124 Enzymes, Predicted intracellular proteins No evidence HPA058345 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +ASIC5 ACCN5, HINAC, INAC ENSG00000256394 Acid sensing ion channel subunit family member 5 4 155829729-155866273 Predicted membrane proteins, Transporters Evidence at protein level HPA014903, HPA029444 Approved Not detected Group enriched 18 duodenum: 2.3;small intestine: 1.2 all non-specific tissues: 0.0 Not detected +TAS2R31 T2R31, T2R53, TAS2R44 ENSG00000256436 Taste 2 receptor member 31 12 11030387-11031407 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Mixed Not detected endometrium,parathyroid gland: 0.3 Not detected +DND1 MGC34750, RBMS4 ENSG00000256453 DND microRNA-mediated repression inhibitor 1 5 140670794-140673586 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 14 testis: 9.8 parathyroid gland: 0.7 Mixed +SALL3 ZNF796 ENSG00000256463 Spalt like transcription factor 3 18 78980275-79002677 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016656 Uncertain Tissue enriched Tissue enhanced cerebral cortex: 4.1;prostate: 2.0 kidney: 0.9 Group enriched 29 HAP1: 4.8;HEK 293: 2.5;NTERA-2: 9.5 +RP11-73M18.2 ENSG00000256500 14 103562962-103685924 Predicted intracellular proteins Evidence at protein level HPA044617, HPA052450 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Not detected Tissue enhanced cerebral cortex: 21.5;testis: 21.6 skeletal muscle: 9.0 Expressed in all +AP003419.11 ENSG00000256514 11 67351572-67373584 Predicted intracellular proteins Evidence at transcript level HPA071529 Uncertain Nucleus
Nucleoli
Mitochondria
Cytosol Not detected Expressed in all tonsil: 101.3 Mixed +POLG2 HP55, MTPOLB ENSG00000256525 DNA polymerase gamma 2, accessory subunit 17 64477785-64497036 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB017030, HPA023202 Approved Approved Nuclear bodies
Mitochondria Liver cancer:1.39e-6 (unfavourable), Renal cancer:1.17e-5 (unfavourable), Prostate cancer:6.59e-4 (unfavourable) Expressed in all Mixed testis: 20.2 Expressed in all +SMIM10L1 ENSG00000256537 Small integral membrane protein 10 like 1 12 11171222-11176016 Predicted intracellular proteins Evidence at transcript level Ovarian cancer:2.71e-4 (favourable), Renal cancer:3.56e-4 (unfavourable), Urothelial cancer:9.70e-4 (favourable) Expressed in all Mixed cerebral cortex: 15.6 Expressed in all +OR13A1 ENSG00000256574 Olfactory receptor family 13 subfamily A member 1 10 45302654-45315608 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA057237 Uncertain Tissue enhanced Not detected urinary bladder: 0.5 Group enriched 16 Daudi: 5.8;U-698: 5.1 +RP11-286N22.8 ENSG00000256591 11 61429220-61485822 Predicted intracellular proteins Evidence at transcript level HPA039732 Uncertain Not detected Mixed cervix, uterine: 9.3 Mixed +MTRNR2L1 ENSG00000256618 MT-RNR2-like 1 17 22523111-22524663 Predicted intracellular proteins Evidence at transcript level Liver cancer:8.99e-4 (favourable) Expressed in all Expressed in all heart muscle: 1105.5 Expressed in all +RP13-672B3.2 ENSG00000256632 12 132688049-132714912 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced duodenum: 2.6 kidney,small intestine,testis: 0.6 Cell line enhanced REH: 1.1;U-698: 1.0 +CLEC12B ENSG00000256660 C-type lectin domain family 12 member B 12 10010627-10018619 Predicted membrane proteins Evidence at protein level Not detected Tissue enhanced testis: 27.0 skin: 5.5 Cell line enriched 14 U-937: 5.5 +LIMS4 LIMS3L ENSG00000256671 LIM zinc finger domain containing 4 2 110446640-110473075 Predicted intracellular proteins Evidence at protein level HPA058455 Uncertain Not detected Not detected kidney,liver: 0.1 Cell line enhanced hTEC/SVTERT24-B: 1.8;U-138 MG: 1.9 +ZNF350 ZBRK1, ZFQR ENSG00000256683 Zinc finger protein 350 19 51964343-51986856 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001521 Uncertain Supported Nucleoplasm
Nuclear bodies Urothelial cancer:2.54e-4 (favourable) Expressed in all Mixed prostate: 45.0 Mixed +PGA5 ENSG00000256713 Pepsinogen 5, group I (pepsinogen A) 11 61241042-61251448 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046875 Supported Tissue enriched Tissue enriched 684 stomach: 3513.1 cerebral cortex: 5.1 Cell line enriched 13 BJ hTERT+: 23.3 +STH MAPTIT ENSG00000256762 Saitohin 17 45999250-45999694 Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced cerebral cortex: 1.4 placenta: 0.5 Not detected +ZNF253 BMZF-1, FLJ90391, ZNF411 ENSG00000256771 Zinc finger protein 253 19 19865886-19894674 Predicted intracellular proteins, Transcription factors Evidence at transcript level Renal cancer:9.69e-5 (favourable), Glioma:1.11e-4 (favourable), Ovarian cancer:2.19e-4 (favourable) Expressed in all Mixed thyroid gland: 25.9 Mixed +KLRF2 NKp65 ENSG00000256797 Killer cell lectin like receptor F2 12 9881489-9895833 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 16 skin: 14.1 tonsil: 0.8 Cell line enriched 40 U-937: 24.5 +C17orf100 LOC388327 ENSG00000256806 Chromosome 17 open reading frame 100 17 6651718-6693202 Predicted intracellular proteins Evidence at protein level HPA046824 Approved Nucleus
Cytokinetic bridge
Cytosol Expressed in all Mixed skin: 8.3 Cell line enhanced SH-SY5Y: 9.8 +CAPNS2 MGC12536, MGC14804 ENSG00000256812 Calpain small subunit 2 16 55566672-55567687 Predicted intracellular proteins Evidence at protein level HPA059749, HPA076768 Enhanced Approved Cytosol Group enriched Tissue enhanced esophagus: 59.9;skin: 109.3 urinary bladder: 30.3 Cell line enriched 8 hTCEpi: 158.7 +CTD-2140B24.4 ENSG00000256825 12 133130984-133202369 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.4 Not detected +SLC5A8 AIT ENSG00000256870 Solute carrier family 5 member 8 12 101155493-101210407 Predicted membrane proteins Evidence at protein level Breast cancer:9.04e-6 (favourable), Renal cancer:1.97e-4 (favourable) Tissue enhanced Tissue enhanced cervix, uterine: 15.0;thyroid gland: 14.7 kidney: 3.5 Cell line enriched 6 SK-BR-3: 2.3 +MTRNR2L7 ENSG00000256892 MT-RNR2-like 7 10 37601440-37602974 Predicted intracellular proteins Evidence at transcript level Not detected Not detected adrenal gland,cerebral cortex,heart muscle,kidney,rectum,skeletal muscle: 0.1 Not detected +LIMS3 ENSG00000256977 LIM zinc finger domain containing 3 2 109898428-109924868 Predicted intracellular proteins Evidence at transcript level HPA058455 Uncertain Approved Focal adhesion sites
Cytosol Not detected Tissue enhanced endometrium: 10.8;fallopian tube: 10.5 appendix: 3.5 Cell line enhanced HEL: 12.7;HMC-1: 36.2 +KHDC1L RP11-257K9.7 ENSG00000256980 KH domain containing 1 like 6 73223544-73225770 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enhanced testis: 4.6 lung: 1.0 Group enriched 8 A-431: 10.2;BEWO: 48.1 +GPR142 PGR2 ENSG00000257008 G protein-coupled receptor 142 17 74367407-74372622 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA031392 Uncertain Uncertain Plasma membrane
Cell Junctions
Cytosol Tissue enhanced Not detected appendix: 0.1 Not detected +HP ENSG00000257017 Haptoglobin 16 72054592-72061055 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB003787, HPA047750 Enhanced Approved Vesicles Renal cancer:6.94e-13 (unfavourable) Tissue enriched Tissue enriched 182 liver: 28407.0 bone marrow: 155.8 Cell line enhanced Hep G2: 153.5;HSkMC: 88.2 +RP11-545J16.1 ENSG00000257046 12 20815674-21090245 Predicted membrane proteins Evidence at transcript level HPA050892 Uncertain Not detected Tissue enriched 13 breast: 26.9 liver: 2.0 Cell line enhanced A-431: 1.4;CAPAN-2: 1.4;HeLa: 1.8 +C11orf97 LINC01171 ENSG00000257057 Chromosome 11 open reading frame 97 11 94512432-94532123 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Group enriched 9 fallopian tube: 28.3;testis: 12.6 lung: 2.3 Not detected +KIAA1147 LCHN ENSG00000257093 KIAA1147 7 141656728-141702153 Predicted intracellular proteins Evidence at protein level HPA029467, HPA061437 Approved Approved Golgi apparatus Head and neck cancer:6.24e-4 (favourable), Renal cancer:8.01e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 21.1 Mixed +LSM14A C19orf13, DKFZP434D1335, FAM61A, RAP55, RAP55A ENSG00000257103 LSM14A, mRNA processing body assembly factor 19 34172504-34229515 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA017961 Approved Supported Cytosol
Cytoplasmic bodies Expressed in all Mixed thyroid gland: 37.5 Cell line enhanced THP-1: 32.4 +NHLRC4 ENSG00000257108 NHL repeat containing 4 16 566996-569495 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced fallopian tube: 18.9 parathyroid gland: 6.3 Cell line enhanced HEL: 3.0;HMC-1: 8.4;RPMI-8226: 2.9 +OR11H12 ENSG00000257115 Olfactory receptor family 11 subfamily H member 12 14 18601045-18602129 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047370 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +CLLU1 ENSG00000257127 Chronic lymphocytic leukemia up-regulated 1 12 92421531-92431002 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +TAS2R38 PTC, T2R61 ENSG00000257138 Taste 2 receptor member 38 7 141972631-141973773 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level HPA043862, HPA054366 Uncertain Not detected Not detected rectum,small intestine: 0.3 Not detected +HOXA10-HOXA9 ENSG00000257184 7 27163535-27180013 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced endometrium: 1.0 prostate: 0.4 Cell line enhanced BJ: 1.1 +GATC 15E1.2, FLJ37000, gatC ENSG00000257218 Glutamyl-tRNA amidotransferase subunit C 12 120446438-120463749 Predicted intracellular proteins Evidence at protein level Liver cancer:4.21e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 20.1 Expressed in all +ZBED6 ENSG00000257315 Zinc finger BED-type containing 6 1 203795714-203854999 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026439, HPA028490, HPA028526, HPA068807 Approved Approved Nucleoplasm
Microtubule organizing center Expressed in all Mixed cervix, uterine: 14.3 Mixed +MGAM MGA ENSG00000257335 Maltase-glucoamylase 7 141907813-142106747 Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA002270 Enhanced Renal cancer:6.16e-5 (favourable) Tissue enriched Tissue enhanced duodenum: 59.4;small intestine: 97.2 epididymis: 31.1 Cell line enhanced A549: 1.6;BJ hTERT+: 1.3;HL-60: 2.2;U-937: 3.4 +FNTB FPTB ENSG00000257365 Farnesyltransferase, CAAX box, beta 14 64986720-65062652 Enzymes, Predicted intracellular proteins Evidence at protein level HPA062743 Approved Approved Centrosome Liver cancer:6.03e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 17.7 Expressed in all +RP11-762I7.5 ENSG00000257390 12 55757275-55827546 Predicted intracellular proteins Evidence at protein level HPA017653, HPA030902, HPA030903 Uncertain Enhanced Nuclear speckles Not detected Tissue enriched 17 testis: 15.2 gallbladder,lymph node: 0.8 Mixed +RP11-603J24.9 ENSG00000257411 12 56101331-56109289 Predicted intracellular proteins Evidence at transcript level Not detected Mixed cervix, uterine: 22.6 Cell line enhanced HBF TERT88: 119.8;LHCN-M2: 60.3;U-698: 57.6 +ZNF878 ENSG00000257446 Zinc finger protein 878 19 12043805-12052939 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA052735 Uncertain Approved Nucleus
Nucleoli Tissue enriched Mixed placenta,testis: 1.0 Mixed +RPL36A-HNRNPH2 ENSG00000257529 RPL36A-HNRNPH2 readthrough X 101391011-101412297 Predicted intracellular proteins Evidence at transcript level HPA077586 Approved Endoplasmic reticulum
Plasma membrane
Cytosol Not detected Mixed ovary: 2.6 Cell line enhanced BJ: 10.0 +ZNF625 ENSG00000257591 Zinc finger protein 625 19 12142090-12156729 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA074014 Approved Nucleus
Mitochondria Mixed Mixed thyroid gland: 4.7 Mixed +GALNT4 GalNAc-T4 ENSG00000257594 Polypeptide N-acetylgalactosaminyltransferase 4 12 89519408-89524806 Enzymes, Predicted intracellular proteins Evidence at protein level HPA076116 Supported Golgi apparatus
Vesicles Mixed Mixed stomach: 31.0 Cell line enhanced PC-3: 20.4 +INAFM1 PRR24 ENSG00000257704 InaF motif containing 1 19 47274453-47275707 Predicted intracellular proteins Evidence at transcript level HPA064015 Uncertain Colorectal cancer:3.20e-5 (unfavourable), Renal cancer:3.04e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 23.3 Expressed in all +CNPY2 Cnpy2, HP10390, TMEM4, ZSIG9 ENSG00000257727 Canopy FGF signaling regulator 2 12 56309842-56316336 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038465, HPA038466 Supported Supported Cytosol Renal cancer:2.32e-8 (unfavourable), Pancreatic cancer:8.37e-4 (favourable) Expressed in all Expressed in all epididymis: 87.4 Expressed in all +MGAM2 ENSG00000257743 Maltase-glucoamylase 2 (putative) 7 142111749-142222324 Enzymes, Predicted membrane proteins Evidence at protein level HPA055697 Enhanced Approved Vesicles
Cytosol Group enriched Group enriched 5 duodenum: 11.8;small intestine: 10.4 salivary gland: 2.1 Cell line enriched 7 RH-30: 1.1 +RP11-162P23.2 ENSG00000257767 12 111753890-111791418 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced adipose tissue: 63.9 stomach: 16.0 Cell line enhanced BEWO: 8.7;EFO-21: 16.7 +RP11-571M6.15 ENSG00000257921 12 57773028-57787046 Predicted intracellular proteins Evidence at transcript level Tissue enriched Not detected lymph node,prostate: 0.1 Cell line enhanced RH-30: 1.2 +CUX1 CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6 ENSG00000257923 Cut like homeobox 1 7 101815904-102283957 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA003277, HPA003317 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:5.72e-7 (favourable), Glioma:9.90e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 82.5 Expressed in all +TEN1 C17orf106, FLJ39785 ENSG00000257949 TEN1, CST complex subunit 17 75979220-76000586 Predicted intracellular proteins Evidence at protein level Not detected Expressed in all skin: 29.9 Expressed in all +LINC00935 ENSG00000257987 Long intergenic non-protein coding RNA 935 12 48727435-48765786 Predicted intracellular proteins Evidence at transcript level Group enriched Tissue enriched 23 testis: 22.3 stomach: 0.9 Not detected +OR9A4 ENSG00000258083 Olfactory receptor family 9 subfamily A member 4 7 141918817-141919909 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.2 Cell line enriched 7 U-937: 1.0 +MAP1LC3B2 ATG8G ENSG00000258102 Microtubule associated protein 1 light chain 3 beta 2 12 116548105-116576448 Predicted intracellular proteins Evidence at transcript level HPA052474, HPA052484, HPA053767 Uncertain Mixed Mixed adrenal gland: 2.7 Cell line enhanced SK-MEL-30: 5.6 +RP11-347C12.3 ENSG00000258130 16 30204316-30209071 Predicted intracellular proteins Evidence at transcript level HPA053608 Uncertain Not detected Tissue enhanced testis: 9.8 salivary gland: 3.8 Group enriched 5 A549: 8.7;CAPAN-2: 31.1;SK-BR-3: 22.1 +RP11-345J4.3 ENSG00000258150 16 29464967-29467833 Predicted intracellular proteins Evidence at transcript level HPA053608 Uncertain Not detected Tissue enhanced testis: 7.0 gallbladder: 4.1 Group enriched 6 A549: 5.4;CAPAN-2: 23.5;SK-BR-3: 15.5 +PRSS58 TRYX3 ENSG00000258223 Protease, serine 58 7 142252143-142258058 Enzymes, Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 123 testis: 21.1 cervix, uterine,smooth muscle: 0.1 Not detected +CLEC5A CLECSF5, MDL-1 ENSG00000258227 C-type lectin domain family 5 member A 7 141927357-141947007 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054137 Supported Plasma membrane
Cytosol Ovarian cancer:2.21e-4 (unfavourable) Mixed Tissue enhanced appendix: 10.6;bone marrow: 27.4 lung: 4.9 Group enriched 29 HL-60: 33.0;U-937: 123.1 +CHURC1 C14orf52, FLJ33064, My015 ENSG00000258289 Churchill domain containing 1 14 64914361-64944591 Predicted intracellular proteins Evidence at protein level HPA040072 Approved Approved Cytosol Expressed in all Expressed in all smooth muscle: 70.4 Expressed in all +RP11-644F5.10 ENSG00000258311 12 55716036-55724703 Predicted intracellular proteins Evidence at transcript level Mixed Mixed adipose tissue: 9.6 Cell line enhanced U-87 MG: 11.2 +C17orf49 BAP18, HEPIS, MGC49942 ENSG00000258315 Chromosome 17 open reading frame 49 17 7014495-7017525 Predicted intracellular proteins Evidence at protein level HPA022961, HPA024457 Supported Uncertain Nucleoplasm
Cytosol Mixed Expressed in all lymph node: 108.5 Expressed in all +RTEL1 bK3184A7.3, C20orf41, DKFZP434C013, KIAA1088, NHL, RTEL ENSG00000258366 Regulator of telomere elongation helicase 1 20 63657810-63696253 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020622, HPA067329, HPA078328 Approved Nuclear speckles
Nuclear bodies Not detected Expressed in all testis: 13.2 Expressed in all +ZNF578 FLJ31384 ENSG00000258405 Zinc finger protein 578 19 52453576-52512154 Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enriched Tissue enriched 5 testis: 14.0 thyroid gland: 2.6 Cell line enhanced NTERA-2: 4.2;U-266/84: 6.8 +RP11-240B13.2 ENSG00000258417 8 132024238-132085655 Predicted membrane proteins No evidence Not detected Not detected cerebral cortex,testis: 0.1 Not detected +PDF ENSG00000258429 Peptide deformylase (mitochondrial) 16 69328621-69330595 Enzymes, Predicted secreted proteins Evidence at protein level HPA063409 Approved Approved Nucleoplasm
Mitochondria Head and neck cancer:2.73e-4 (unfavourable), Cervical cancer:4.63e-4 (unfavourable), Renal cancer:6.11e-4 (favourable), Lung cancer:7.35e-4 (unfavourable) Expressed in all Expressed in all kidney: 7.8 Expressed in all +RNASE12 RAI1 ENSG00000258436 Ribonuclease A family member 12 (inactive) 14 20590193-20590823 Predicted secreted proteins Evidence at protein level HPA044175, HPA059465 Enhanced Uncertain Vesicles
Microtubules Not detected Tissue enriched 252 epididymis: 1052.1 seminal vesicle: 4.1 Not detected +OR11H2 C14orf15, OR11H2P, OR11H8P ENSG00000258453 Olfactory receptor family 11 subfamily H member 2 14 19712936-19713920 G-protein coupled receptors, Predicted membrane proteins No evidence HPA047370 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +RP11-574F21.3 ENSG00000258465 1 160217464-160285130 Predicted intracellular proteins Evidence at protein level HPA027218, HPA027381, HPA044837 Approved Approved Nucleoplasm
Cytosol Not detected Mixed heart muscle: 2.5 Cell line enhanced EFO-21: 3.9;HDLM-2: 3.7 +RP11-1012A1.4 ENSG00000258466 14 67659820-67690367 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Not detected appendix,gallbladder,urinary bladder: 0.5 Cell line enhanced SK-BR-3: 1.0 +RP11-192H23.4 ENSG00000258472 17 28455752-28614197 Predicted intracellular proteins Evidence at protein level HPA046590 Uncertain Approved Nucleoplasm
Vesicles
Plasma membrane Mixed Tissue enhanced cerebral cortex: 2.2 lung: 1.2 Cell line enhanced A549: 2.3;PC-3: 1.1 +SPESP1 SP-ESP ENSG00000258484 Sperm equatorial segment protein 1 15 68818221-68946811 Predicted secreted proteins Evidence at protein level HPA045936, HPA051040 Enhanced Expressed in all Tissue enriched 7 testis: 128.4 placenta: 18.0 Cell line enhanced BJ hTERT+ SV40 Large T+: 16.1;BJ hTERT+ SV40 Large T+ RasG12V: 17.7;HBF TERT88: 20.5;RPTEC TERT1: 19.6;SCLC-21H: 23.0;WM-115: 30.5 +RP11-108O10.8 ENSG00000258529 11 111786286-111879425 Predicted membrane proteins Evidence at protein level HPA038575 Uncertain Approved Endoplasmic reticulum Not detected Tissue enhanced testis: 1.7 skin: 0.9 Cell line enhanced CACO-2: 2.3 +TRIM6-TRIM34 ENSG00000258588 TRIM6-TRIM34 readthrough 11 5596725-5644398 Predicted intracellular proteins Evidence at transcript level HPA077996 Approved Nucleoli
Centrosome Not detected Not detected testis: 0.6 Cell line enriched 7 A549: 4.1 +BCL2L2-PABPN1 ENSG00000258643 BCL2L2-PABPN1 readthrough 14 23306835-23325369 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level HPA000637 Approved Approved Mixed Mixed seminal vesicle: 29.3 Mixed +SYNJ2BP-COX16 ENSG00000258644 SYNJ2BP-COX16 readthrough 14 70326064-70417074 Predicted intracellular proteins Evidence at protein level HPA000866, HPA062659 Approved Supported Enhanced Mitochondria Not detected Tissue enhanced testis: 39.7 skeletal muscle: 15.1 Mixed +TRIM34 RNF21 ENSG00000258659 Tripartite motif containing 34 11 5619764-5644398 Predicted intracellular proteins Evidence at protein level HPA077996 Approved Nucleoli
Centrosome Not detected Mixed spleen: 18.5 Mixed +CTC-260F20.3 ENSG00000258674 19 19516227-19536076 Predicted membrane proteins Evidence at transcript level Mixed Mixed cerebral cortex: 4.6 Cell line enhanced BEWO: 23.4 +RP11-404P21.8 ENSG00000258691 14 96204844-96263929 Predicted intracellular proteins Evidence at transcript level Not detected Mixed esophagus,gallbladder: 1.4 Cell line enhanced BJ hTERT+: 5.0;HaCaT: 2.5;U-87 MG: 3.9 +C20orf141 dJ860F19.4 ENSG00000258713 Chromosome 20 open reading frame 141 20 2814987-2815833 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 105 testis: 97.0 placenta: 0.9 Group enriched 11 HDLM-2: 18.6;U-2197: 4.7 +CTD-2135J3.4 ENSG00000258724 8 10725399-10839847 Predicted intracellular proteins Evidence at protein level HPA009065 Uncertain Approved Nuclear speckles
Golgi apparatus Not detected Not detected adipose tissue,lung: 0.5 Cell line enhanced HaCaT: 1.3 +RP11-195F19.29 ENSG00000258728 9 34646645-34657113 Predicted intracellular proteins No evidence Not detected Not detected fallopian tube: 0.3 Not detected +OR4C13 ENSG00000258817 Olfactory receptor family 4 subfamily C member 13 11 49952391-49953419 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +RNASE4 RAB1 ENSG00000258818 Ribonuclease A family member 4 14 20684100-20701215 Plasma proteins, Predicted secreted proteins Evidence at protein level Liver cancer:9.62e-5 (favourable) Tissue enhanced Tissue enhanced liver: 232.5 prostate: 117.7 Cell line enhanced ASC diff: 59.9;ASC TERT1: 68.7;Hep G2: 89.2;HSkMC: 42.8 +MC1R MSH-R ENSG00000258839 Melanocortin 1 receptor 16 89912119-89920977 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Pancreatic cancer:7.88e-4 (favourable) Tissue enhanced Tissue enhanced testis: 13.7 skin: 6.9 Cell line enhanced SK-MEL-30: 28.3 +DUXA ENSG00000258873 Double homeobox A 19 57154021-57167443 Predicted intracellular proteins, Transcription factors No evidence HPA059358 Uncertain Not detected Not detected appendix,testis: 0.3 Not detected +AC007040.11 ENSG00000258881 2 70939318-70995336 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced testis: 1.1 skin: 0.7 Cell line enhanced U-2 OS: 2.3 +CEP95 CCDC45, DKFZp667E1824 ENSG00000258890 Centrosomal protein 95 17 64506588-64542461 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023654, HPA052426, HPA052428, HPA061371 Approved Approved Nucleoplasm
Vesicles
Mitotic spindle
Centrosome Liver cancer:2.52e-5 (unfavourable), Renal cancer:5.76e-5 (unfavourable), Head and neck cancer:5.78e-4 (favourable) Expressed in all Expressed in all endometrium: 27.7 Expressed in all +RP11-407N17.3 ENSG00000258941 CTAGE family member 5 isoform 8 precursor 14 39233902-39350423 Predicted membrane proteins Evidence at protein level HPA000387, HPA000922, HPA054066, HPA055459 Uncertain Approved Endoplasmic reticulum Not detected Tissue enhanced duodenum: 23.9;liver: 22.8;parathyroid gland: 44.1;small intestine: 29.5 kidney: 19.0 Cell line enhanced CAPAN-2: 17.3;EFO-21: 5.5;Hep G2: 8.5;RPTEC TERT1: 7.0 +TUBB3 beta-4, CFEOM3, CFEOM3A, FEOM3 ENSG00000258947 Tubulin beta 3 class III 16 89921392-89938761 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043640, HPA046280 Approved Mixed Tissue enriched 6 cerebral cortex: 195.6 adrenal gland: 34.5 Cell line enhanced SCLC-21H: 490.8 +RP11-934B9.3 ENSG00000258973 14 24332310-24337382 Predicted intracellular proteins Evidence at protein level HPA055087 Uncertain Not detected Not detected placenta,skin: 0.5 Not detected +TMEM179 C14orf90, FLJ42486, TMEM179A ENSG00000258986 Transmembrane protein 179 14 104474678-104605647 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at transcript level HPA002942 Uncertain Mitochondria Mixed Group enriched 8 adrenal gland: 14.6;cerebral cortex: 27.9 testis: 2.5 Cell line enhanced NTERA-2: 8.5;SCLC-21H: 42.8;SH-SY5Y: 12.2 +RP11-47I22.4 ENSG00000258989 14 61529128-61657964 Predicted intracellular proteins Evidence at transcript level Not detected Mixed epididymis: 12.7 Cell line enhanced U-2 OS: 31.5 +TSPY1 CT78, TSPY ENSG00000258992 Testis specific protein, Y-linked 1 Y 9466955-9469748 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049384 Supported Tissue enriched Tissue enriched 84 testis: 8.3 all non-specific tissues: 0.0 Group enriched 298 U-266/70: 186.9;U-266/84: 172.0 +TVP23C-CDRT4 FAM18B2-CDRT4 ENSG00000259024 TVP23C-CDRT4 readthrough 17 15436021-15563561 Predicted membrane proteins Evidence at transcript level HPA065603 Approved Golgi apparatus Not detected Mixed parathyroid gland: 11.8 Mixed +FPGT-TNNI3K ENSG00000259030 FPGT-TNNI3K readthrough 1 74198235-74543982 Predicted intracellular proteins Evidence at protein level HPA072331 Approved Vesicles Not detected Mixed heart muscle: 5.7 Cell line enhanced SiHa: 3.3 +RP11-14J7.7 ENSG00000259060 Probable ribonuclease 11 precursor 14 20582892-20609795 Predicted secreted proteins Evidence at transcript level Not detected Group enriched 34 epididymis: 5.4;testis: 1.2 all non-specific tissues: 0.0 Not detected +RP11-371E8.4 ENSG00000259066 14 93184973-93218586 Predicted intracellular proteins No evidence Not detected Not detected skeletal muscle: 0.2 Not detected +POC1B-GALNT4 ENSG00000259075 POC1B-GALNT4 readthrough 12 89519408-89526262 Predicted intracellular proteins Evidence at transcript level HPA076116 Not detected Mixed appendix,gallbladder: 2.2 Cell line enhanced AN3-CA: 10.0 +NDUFC2-KCTD14 ENSG00000259112 NDUFC2-KCTD14 readthrough 11 78016971-78079865 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038873, HPA056195 Approved Supported Mitochondria Not detected Tissue enhanced duodenum: 5.0 stomach: 2.5 Cell line enhanced CACO-2: 7.9;EFO-21: 7.0;U-2 OS: 12.0 +SMIM6 C17orf110 ENSG00000259120 Small integral membrane protein 6 17 75646243-75647977 Predicted membrane proteins Evidence at transcript level HPA065721 Uncertain Approved Nucleus Endometrial cancer:1.49e-4 (favourable), Urothelial cancer:1.64e-4 (favourable), Renal cancer:4.09e-4 (favourable) Mixed Tissue enhanced fallopian tube: 40.3;stomach: 34.4 testis: 22.6 Cell line enhanced A549: 10.7;EFO-21: 8.5;HEL: 6.1 +RP11-298I3.5 ENSG00000259132 14 22946270-22982258 Predicted intracellular proteins Evidence at protein level HPA029803 Approved Approved Plasma membrane
Focal adhesion sites Not detected Mixed skin: 9.3 Cell line enhanced Hep G2: 29.1 +RP11-903H12.5 ENSG00000259171 14 20684587-20700576 Predicted secreted proteins Evidence at transcript level Mixed Mixed ovary: 96.7 Cell line enhanced ASC diff: 15.5;ASC TERT1: 33.6;Hep G2: 21.7;HSkMC: 15.5 +ITGB3 CD61, GP3A, GPIIIa ENSG00000259207 Integrin subunit beta 3 17 47253846-47311816 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA027852 Supported Group enriched Tissue enhanced thyroid gland: 95.6 smooth muscle: 36.8 Cell line enhanced EFO-21: 179.0;HEL: 158.0;WM-115: 275.8 +SLC35G6 AMAC1L3, TMEM21B ENSG00000259224 Solute carrier family 35 member G6 17 7481332-7483496 Predicted membrane proteins, Transporters Evidence at transcript level Not detected Tissue enriched 17 testis: 1.7 all non-specific tissues: 0.0 Not detected +BUB1B-PAK6 ENSG00000259288 BUB1B-PAK6 readthrough 15 40217428-40276396 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA031124 Uncertain Approved Nucleus
Nucleoli fibrillar center
Cell Junctions Not detected Not detected cerebral cortex: 0.1 Not detected +ZHX1-C8orf76 ENSG00000259305 ZHX1-C8orf76 readthrough 8 123226189-123274284 Predicted intracellular proteins Evidence at transcript level HPA023708 Uncertain Uncertain Nucleoplasm
Cytosol Mixed Mixed bone marrow: 5.3 Cell line enhanced SK-BR-3: 19.4 +CTD-2116N17.1 ENSG00000259316 15 64181180-64381510 Predicted intracellular proteins Evidence at transcript level HPA047929 Uncertain Centrosome Not detected Tissue enhanced lymph node: 31.6;tonsil: 21.4 bone marrow: 14.1 Cell line enhanced HAP1: 299.5 +INAFM2 LINC00984, OGU1 ENSG00000259330 InaF motif containing 2 15 40323664-40326715 Predicted membrane proteins Evidence at transcript level Renal cancer:1.88e-7 (unfavourable), Stomach cancer:5.01e-4 (unfavourable), Lung cancer:7.87e-4 (favourable) Expressed in all Expressed in all thyroid gland: 44.5 Expressed in all +ST20-MTHFS ENSG00000259332 ST20-MTHFS readthrough 15 79845150-79923754 Predicted intracellular proteins Evidence at protein level HPA008067 Uncertain Not detected Mixed parathyroid gland: 15.1 Mixed +RP11-468E2.6 ENSG00000259371 14 24120956-24131829 Predicted membrane proteins No evidence Not detected Not detected small intestine,testis: 0.5 Not detected +GH1 GH, GH-N, GHN, hGH-N ENSG00000259384 Growth hormone 1 17 63917200-63918838 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043715 Supported Not detected Tissue enhanced placenta: 1.2 duodenum: 0.6 Cell line enhanced U-698: 1.8 +TGIF2-C20orf24 ENSG00000259399 TGIF2-C20orf24 readthrough 20 36574553-36612384 Predicted membrane proteins Evidence at transcript level Not detected Mixed appendix: 11.2 Mixed +LINC01314 ENSG00000259417 Long intergenic non-protein coding RNA 1314 15 80195484-80252213 Predicted membrane proteins Evidence at transcript level Group enriched Tissue enhanced cerebral cortex: 5.7;epididymis: 6.6 liver: 4.8 Group enriched 7 SK-MEL-30: 1.2;WM-115: 4.7 +THTPA THTPASE ENSG00000259431 Thiamine triphosphatase 14 23555988-23560271 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028876 Approved Uncertain Nucleus
Nucleoli Renal cancer:1.70e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 33.5 Expressed in all +MRPL46 C15orf4, LIECG2, P2ECSL ENSG00000259494 Mitochondrial ribosomal protein L46 15 88459476-88467419 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050166 Uncertain Supported Nucleoplasm
Cell Junctions
Mitochondria Renal cancer:2.09e-6 (favourable) Expressed in all Expressed in all adrenal gland: 50.3 Expressed in all +UBE2Q2L ENSG00000259511 Ubiquitin conjugating enzyme E2 Q2 like 15 84172490-84182234 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced ovary: 2.2 testis: 1.2 Cell line enhanced K-562: 2.0;Karpas-707: 1.3 +BLID BRCC2 ENSG00000259571 BH3-like motif containing, cell death inducer 11 122115354-122116215 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Cell line enhanced hTEC/SVTERT24-B: 1.0;LHCN-M2: 1.2;U-87 MG: 1.7 +RP11-812E19.9 ENSG00000259680 16 33844784-33845229 Predicted secreted proteins Evidence at transcript level Head and neck cancer:6.96e-5 (favourable) Mixed Tissue enhanced tonsil: 23.0 urinary bladder: 12.1 Not detected +RP11-20I23.3 ENSG00000259784 16 2513965-2527955 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced bone marrow: 1.1;small intestine: 1.3 smooth muscle: 0.5 Cell line enhanced REH: 1.4 +SLC22A31 ENSG00000259803 Solute carrier family 22 member 31 16 89195761-89201664 Predicted membrane proteins Evidence at transcript level Group enriched Tissue enriched 7 lung: 23.0 pancreas: 3.4 Cell line enhanced BEWO: 33.0;Hep G2: 19.4;NB-4: 9.3;RPMI-8226: 11.9 +LYPD8 ENSG00000259823 LY6/PLAUR domain containing 8 1 248718649-248755739 Predicted secreted proteins Evidence at protein level Tissue enriched Group enriched 12 colon: 216.6;rectum: 141.8 appendix: 14.4 Not detected +RP11-407P15.2 ENSG00000259916 2 94588522-94604573 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 13 adipose tissue: 7.6 kidney: 0.5 Cell line enriched 9 ASC diff: 1.3 +RBM15B HUMAGCGB, OTT3 ENSG00000259956 RNA binding motif protein 15B 3 51391268-51397908 Predicted intracellular proteins Evidence at protein level HPA036645, HPA058136 Approved Enhanced Nucleoplasm Renal cancer:1.84e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 23.1 Expressed in all +TGFBR3L ENSG00000260001 Transforming growth factor beta receptor 3 like 19 7916145-7919097 Predicted membrane proteins Evidence at protein level HPA074356 Supported Approved Vesicles Mixed Tissue enhanced duodenum: 1.7;small intestine: 1.8 kidney: 1.0 Cell line enhanced PC-3: 3.7;REH: 9.0 +RP11-315D16.2 ENSG00000260007 15 68184032-68229718 Predicted intracellular proteins Evidence at transcript level Not detected Not detected seminal vesicle,smooth muscle: 0.5 Cell line enhanced BJ hTERT+: 1.3;HAP1: 1.7;HEK 293: 2.7 +HOXB7 HOX2, HOX2C ENSG00000260027 Homeobox B7 17 48607227-48633572 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049940 Uncertain Supported Nucleoplasm
Nuclear bodies
Cytosol Urothelial cancer:2.39e-4 (favourable) Mixed Tissue enriched 5 epididymis: 162.9 cervix, uterine: 32.1 Cell line enhanced EFO-21: 76.4;SK-MEL-30: 62.0 +SPDYE6 ENSG00000260097 Speedy/RINGO cell cycle regulator family member E6 7 102347206-102356444 Predicted intracellular proteins Evidence at protein level HPA051750 Approved Mixed Tissue enhanced testis: 6.6 skin: 3.9 Mixed +RP11-96O20.4 ENSG00000260170 15 45587351-45676314 Predicted intracellular proteins Evidence at transcript level HPA041589 Uncertain Not detected Not detected colon: 0.7 Cell line enhanced HBEC3-KT: 1.8;HDLM-2: 1.4 +CCDC187 MGC50722 ENSG00000260220 Coiled-coil domain containing 187 9 136249971-136306901 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enhanced fallopian tube: 12.2;testis: 14.7 epididymis: 3.4 Group enriched 6 RPMI-8226: 7.1;SCLC-21H: 3.6 +FRRS1L C9orf4, CG-6 ENSG00000260230 Ferric chelate reductase 1 like 9 109130293-109167291 Disease related genes, Predicted membrane proteins Evidence at protein level HPA071086 Enhanced Mixed Tissue enhanced cerebral cortex: 47.7 ovary: 14.2 Cell line enhanced AF22: 1.6;SH-SY5Y: 4.3 +PMF1-BGLAP ENSG00000260238 PMF1-BGLAP readthrough 1 156212982-156243332 Predicted intracellular proteins Evidence at protein level HPA034583, HPA071854 Approved Nucleoplasm
Vesicles Liver cancer:1.50e-4 (unfavourable), Renal cancer:3.22e-4 (unfavourable) Mixed Mixed fallopian tube: 8.2 Expressed in all +RP11-20I23.1 ENSG00000260272 16 2496032-2520218 Predicted membrane proteins Evidence at transcript level HPA044712 Uncertain Not detected Not detected cerebral cortex: 0.7 Cell line enhanced HEK 293: 1.5;SCLC-21H: 1.9;SH-SY5Y: 1.9 +C6orf229 ENSG00000260286 Chromosome 6 open reading frame 229 6 24797321-24798889 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 12 testis: 21.8 lung: 1.7 Not detected +TBC1D3G ENSG00000260287 TBC1 domain family member 3G 17 36323884-36334759 Predicted membrane proteins Evidence at protein level HPA046969, HPA047745, HPA052553 Supported Approved Vesicles Not detected Tissue enriched 33 testis: 6.1 duodenum: 0.1 Cell line enhanced SiHa: 1.4 +RP11-505K9.4 ENSG00000260300 16 83908132-83951445 Predicted intracellular proteins Evidence at transcript level Not detected Mixed heart muscle: 2.7 Mixed +MRC1 bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1 ENSG00000260314 Mannose receptor C-type 1 10 17809344-17911170 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA004114, HPA045134, CAB068203 Enhanced Expressed in all Tissue enhanced lung: 179.9 placenta: 77.6 Group enriched 22 MOLT-4: 15.4;TIME: 14.0 +HSPB9 CT51 ENSG00000260325 Heat shock protein family B (small) member 9 17 42121431-42123352 Predicted intracellular proteins Evidence at protein level Mixed Tissue enriched 14 testis: 6.7 appendix,liver,ovary: 0.4 Mixed +RP11-1035H13.3 ENSG00000260342 16 18788063-18801519 Predicted membrane proteins Evidence at transcript level HPA045307 Uncertain Approved Endoplasmic reticulum Mixed Tissue enhanced testis: 25.8 cerebral cortex: 7.0 Cell line enhanced HDLM-2: 82.4 +RP11-343C2.9 ENSG00000260371 16 69335091-69356306 Predicted intracellular proteins Evidence at transcript level Not detected Mixed testis: 2.1 Mixed +SCX bHLHa41, bHLHa48, SCXA, SCXB ENSG00000260428 Scleraxis bHLH transcription factor 8 144266560-144268481 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA043183 Uncertain Glioma:2.46e-4 (unfavourable) Group enriched Tissue enhanced skeletal muscle: 5.3 parathyroid gland: 2.9 Cell line enhanced BEWO: 4.9;HaCaT: 5.0 +C16orf95 ENSG00000260456 Chromosome 16 open reading frame 95 16 87083562-87317420 Predicted intracellular proteins Evidence at protein level HPA040850, HPA067924 Supported Approved Endoplasmic reticulum Mixed Tissue enriched 24 testis: 80.4 cerebral cortex: 3.2 Mixed +KCNJ18 KIR2.6, TTPP2 ENSG00000260458 Potassium voltage-gated channel subfamily J member 18 17 21692523-21704612 Disease related genes, Predicted membrane proteins Evidence at protein level HPA027021 Uncertain Uncertain Nucleoplasm
Golgi apparatus
Cytosol Tissue enhanced Group enriched 8 skin: 3.8;tonsil: 1.3 testis: 0.3 Not detected +RP11-529K1.3 ENSG00000260537 16 70299194-70372582 Predicted intracellular proteins Evidence at protein level HPA046380, HPA066668 Approved Uncertain Nucleoplasm Not detected Mixed urinary bladder: 7.1 Mixed +RP6-24A23.6 ENSG00000260548 X 108722070-108732687 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced ovary: 12.9;thyroid gland: 12.5 endometrium: 5.6 Cell line enhanced HEK 293: 15.4;NTERA-2: 2.4;RT4: 3.5;WM-115: 4.3 +DUX4 ENSG00000260596 Double homeobox 4 4 190173774-190185942 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters Evidence at protein level HPA058451 Supported Nucleus
Nucleoli
Golgi apparatus
Cytosol Not detected Tissue enhanced testis: 1.4 prostate: 0.4 Cell line enhanced A549: 1.3;U-2 OS: 2.2;U-266/70: 3.6;U-266/84: 4.6 +RP11-303E16.8 ENSG00000260643 16 81053587-81096296 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041368 Approved Approved Vesicles Mixed Tissue enhanced thyroid gland: 17.3 cerebral cortex: 11.3 Mixed +ANKRD20A1 ANKRD20A, DKFZp434A171 ENSG00000260691 Ankyrin repeat domain 20 family member A1 9 67859147-67902094 Predicted intracellular proteins Evidence at transcript level HPA043239, HPA047112, HPA047167, HPA047766, HPA051753 Uncertain Not detected Tissue enriched 7 testis: 5.2 cerebral cortex,spleen: 0.7 Cell line enhanced Karpas-707: 3.2;U-266/70: 5.6;U-266/84: 1.9 +RP11-510M2.4 ENSG00000260734 16 71430262-71433376 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 18 testis: 1.8 all non-specific tissues: 0.0 Not detected +LINC00890 ENSG00000260802 Long intergenic non-protein coding RNA 890 X 111511662-111522399 Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced endometrium: 44.1;epididymis: 51.0;seminal vesicle: 107.2 prostate: 15.9 Cell line enhanced HMC-1: 14.8;NTERA-2: 2.9;SCLC-21H: 3.3 +RP11-152F13.10 ENSG00000260836 15 82540032-82555932 Predicted intracellular proteins Evidence at transcript level Not detected Not detected cerebral cortex,parathyroid gland: 0.2 Cell line enriched 26 U-2197: 19.4 +RP4-576H24.4 ENSG00000260861 20 1540144-1620009 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level Not detected Tissue enhanced appendix: 3.3;cerebral cortex: 4.5 testis: 2.5 Cell line enhanced HL-60: 2.6;HMC-1: 5.9;NB-4: 1.4;THP-1: 1.8;U-937: 1.5 +AC002310.13 ENSG00000260869 16 30534227-30558279 Predicted intracellular proteins Evidence at transcript level Not detected Not detected adipose tissue,colon,duodenum,small intestine,spleen: 0.5 Cell line enhanced A549: 1.2 +XKR7 C20orf159, dJ310O13.4 ENSG00000260903 XK related 7 20 31968002-32003387 Predicted membrane proteins Evidence at protein level HPA040854 Uncertain Not detected Tissue enriched 10 cerebral cortex: 3.6 adrenal gland,testis: 0.3 Group enriched 18 SCLC-21H: 24.2;SH-SY5Y: 4.9 +RP11-343C2.11 ENSG00000260914 16 69299682-69322700 Predicted intracellular proteins Evidence at protein level HPA060092 Uncertain Midbody Not detected Expressed in all cerebral cortex: 85.3 Expressed in all +CCPG1 CPR8, KIAA1254 ENSG00000260916 Cell cycle progression 1 15 55340032-55408510 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009432, HPA026861 Approved Approved Endoplasmic reticulum
Golgi apparatus Stomach cancer:5.02e-5 (unfavourable), Renal cancer:5.07e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 140.4 Cell line enhanced Karpas-707: 242.3 +SULT1A3 STM, TL-PST ENSG00000261052 Sulfotransferase family 1A member 3 16 30199228-30204310 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049500, HPA051051 Supported Not detected Expressed in all duodenum: 106.1 Expressed in all +TMEM178B DKFZp547G036 ENSG00000261115 Transmembrane protein 178B 7 141074232-141480380 Predicted membrane proteins Evidence at protein level HPA048771 Uncertain Uncertain Nucleoli
Vesicles Renal cancer:4.10e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 19.3;parathyroid gland: 28.9;thyroid gland: 14.4 heart muscle: 7.2 Cell line enhanced HAP1: 6.3;RPTEC TERT1: 6.3;SCLC-21H: 7.7;WM-115: 8.9 +RP11-1021N1.1 ENSG00000261130 16 15395754-15515348 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +EPPK1 EPIPL1 ENSG00000261150 Epiplakin 1 8 143857324-143878464 Predicted intracellular proteins Evidence at protein level HPA066808, HPA067357, HPA069333 Approved Enhanced Intermediate filaments Endometrial cancer:5.52e-5 (unfavourable), Pancreatic cancer:3.94e-4 (unfavourable) Mixed Tissue enhanced skin: 11.2 small intestine: 2.9 Cell line enhanced BEWO: 13.8;EFO-21: 12.5;HaCaT: 12.0;HeLa: 15.1;MCF7: 15.3 +CLEC19A ENSG00000261210 C-type lectin domain family 19 member A 16 19285739-19322145 Predicted secreted proteins Evidence at transcript level Not detected Tissue enriched 8 cerebral cortex: 3.2 skin: 0.4 Not detected +ZNF865 ENSG00000261221 Zinc finger protein 865 19 55605405-55617269 Predicted intracellular proteins Evidence at protein level HPA068079 Approved Approved Nucleus
Nucleoli Expressed in all Mixed skeletal muscle: 8.4 Expressed in all +BOP1 KIAA0124 ENSG00000261236 Block of proliferation 1 8 144262102-144291370 Predicted intracellular proteins Evidence at protein level HPA047869, HPA066764 Approved Enhanced Nucleus
Nucleoli Renal cancer:2.23e-7 (unfavourable), Liver cancer:3.35e-5 (unfavourable) Expressed in all Expressed in all appendix: 24.4 Expressed in all +GOLGA8T ENSG00000261247 Golgin A8 family member T 15 30135149-30145567 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +MUC22 PBMUCL1 ENSG00000261272 Mucin 22 6 31010474-31035402 Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 116 esophagus: 20.2 testis,tonsil: 0.1 Not detected +FIGNL2 ENSG00000261308 Fidgetin like 2 12 51817840-51848766 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced kidney: 2.3;parathyroid gland: 2.4 placenta: 1.1 Cell line enhanced AF22: 17.1;BEWO: 10.8;NTERA-2: 6.9 +CTD-2568A17.1 ENSG00000261341 19 50776141-50793142 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 11 testis: 108.1 skin: 9.5 Cell line enhanced AF22: 4.0;HEK 293: 5.0 +PECAM1 CD31 ENSG00000261371 Platelet and endothelial cell adhesion molecule 1 17 64319415-64413776 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004690 Supported Renal cancer:8.98e-5 (unfavourable) Expressed in all Expressed in all placenta: 659.7 Cell line enhanced HUVEC TERT2: 644.6;TIME: 437.4 +TEN1-CDK3 ENSG00000261408 TEN1-CDK3 readthrough (NMD candidate) 17 75979231-76005999 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced small intestine: 1.4 adipose tissue,spleen: 1.1 Cell line enhanced BEWO: 2.6;SH-SY5Y: 3.9 +TUBB8 bA631M21.2 ENSG00000261456 Tubulin beta 8 class VIII 10 46892-74163 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043640, HPA046280 Uncertain Tissue enriched Tissue enhanced testis: 1.0 parathyroid gland: 0.8 Cell line enhanced MCF7: 1.1 +TP53TG3B ENSG00000261509 TP53 target 3B 16 33360274-33363478 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 18 epididymis: 22.3 testis: 1.2 Not detected +TMEM249 C8orfK29 ENSG00000261587 Transmembrane protein 249 8 144352219-144354914 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 27 testis: 9.3 epididymis: 0.3 Mixed +TPBGL ENSG00000261594 Trophoblast glycoprotein-like 11 75240905-75243697 Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced cerebral cortex: 3.1;testis: 5.0 adrenal gland: 2.3 Cell line enhanced AF22: 1.5;HMC-1: 1.7;SCLC-21H: 2.2 +PRSS46 TESSP6 ENSG00000261603 Protease, serine 46 3 46719583-46736429 Enzymes, Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced epididymis: 4.5;testis: 8.4 parathyroid gland: 2.7 Not detected +GAN GAN1, KLHL16 ENSG00000261609 Gigaxonin 16 81314952-81390884 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011825, HPA049473 Approved Supported Microtubules Mixed Tissue enriched 6 skin: 29.5 cerebral cortex: 5.0 Mixed +GOLGA6L7P GOLGA6L7 ENSG00000261649 Golgin A6 family-like 7, pseudogene 15 28841833-28848675 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 53 testis: 25.5 cerebral cortex: 0.4 Not detected +C15orf65 FLJ27352 ENSG00000261652 Chromosome 15 open reading frame 65 15 55408548-55418764 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level HPA067189 Approved Approved Nucleus
Cytosol Endometrial cancer:3.18e-7 (favourable) Expressed in all Mixed testis: 16.9 Mixed +LY6L ENSG00000261667 Lymphocyte antigen 6 family member L 8 143080457-143083001 Predicted secreted proteins Evidence at transcript level Tissue enriched Tissue enhanced epididymis: 1.1 seminal vesicle: 0.7 Not detected +SCRT1 DKFZp547F072, ZNF898 ENSG00000261678 Scratch family transcriptional repressor 1 8 144330565-144336281 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045265 Uncertain Supported Nuclear bodies Tissue enhanced Tissue enriched 7 cerebral cortex: 10.9 adrenal gland: 1.5 Group enriched 12 SCLC-21H: 11.4;SH-SY5Y: 2.3 +HPR ENSG00000261701 Haptoglobin-related protein 16 72063224-72077246 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA047750 Supported Approved Vesicles Tissue enriched Tissue enriched 24 liver: 444.1 heart muscle: 18.7 Cell line enriched 14 Hep G2: 34.3 +RP11-77K12.1 ENSG00000261717 16 75412684-75464706 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA041316, HPA055071 Uncertain Not detected Not detected testis: 0.8 Cell line enhanced REH: 4.3;U-698: 13.9 +GOLGA8S ENSG00000261739 Golgin A8 family member S 15 23354748-23367231 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.7 Not detected +RP11-345J4.5 ENSG00000261740 BOLA2-SMG1P6 protein isoform a 16 29443230-29454651 Predicted intracellular proteins Evidence at transcript level Expressed in all Expressed in all lymph node: 17.7 Expressed in all +TCF24 bHLHa25 ENSG00000261787 Transcription factor 24 8 66946501-66962590 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced kidney: 1.2;testis: 2.8 fallopian tube: 0.7 Cell line enhanced HAP1: 2.2;HEK 293: 5.0;HMC-1: 4.1 +RP11-350O14.18 ENSG00000261793 9 137168854-137171984 Predicted secreted proteins Evidence at transcript level Not detected Group enriched 7 prostate: 17.4;salivary gland: 23.0 small intestine: 2.8 Cell line enhanced REH: 9.4;RPMI-8226: 11.9;SK-BR-3: 8.3;T-47d: 6.0 +GOLGA8H GOLGA6L11 ENSG00000261794 Golgin A8 family member H 15 30604126-30614561 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced testis: 8.5 fallopian tube,thyroid gland: 1.8 Cell line enhanced HMC-1: 2.5;RH-30: 3.9;SH-SY5Y: 2.4 +ISY1-RAB43 ENSG00000261796 ISY1-RAB43 readthrough 3 129087575-129161036 Predicted intracellular proteins Evidence at protein level HPA006312, HPA016995 Approved Enhanced Nuclear speckles Not detected Expressed in all parathyroid gland: 14.1 Mixed +RP11-435I10.4 ENSG00000261832 16 28456371-28492098 Predicted membrane proteins Evidence at protein level HPA053611 Uncertain Approved Nucleoplasm Not detected Not detected smooth muscle: 0.1 Not detected +MIA CD-RAP ENSG00000261857 Melanoma inhibitory activity 19 40771648-40777490 Cancer-related genes, Predicted secreted proteins Evidence at protein level HPA031950, HPA042369 Supported Supported Breast cancer:2.08e-4 (favourable) Tissue enriched Tissue enhanced breast: 62.9;stomach: 50.0 salivary gland: 18.4 Group enriched 41 AN3-CA: 79.3;CAPAN-2: 63.4;SK-MEL-30: 198.0;WM-115: 233.6 +RP11-515E23.1 ENSG00000261873 17 55448433-55511444 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 17 testis: 2.5 bone marrow,cerebral cortex,spleen: 0.1 Not detected +PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 Protocadherin gamma subfamily A, 9 5 141402932-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Tissue enhanced Tissue enhanced cerebral cortex: 9.6 endometrium: 4.1 Cell line enhanced EFO-21: 3.4;TIME: 3.7;U-87 MG: 5.0 +GFY Goofy ENSG00000261949 Golgi associated olfactory signaling regulator 19 49423749-49428818 Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced testis: 1.0 cerebral cortex: 0.2 Group enriched 6 HEK 293: 1.7;SCLC-21H: 5.3;T-47d: 1.1;U-266/84: 2.0 +RP11-81A22.5 ENSG00000262165 17 4801159-4807013 Predicted intracellular proteins Evidence at transcript level Mixed Mixed ovary: 3.1 Cell line enhanced AN3-CA: 3.1;SCLC-21H: 12.1 +RP1-302G2.5 ENSG00000262179 Homo sapiens uncharacterized LOC101929726 (LOC101929726), transcript variant 2, mRNA. 6 44216939-44218236 Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enhanced adipose tissue: 5.7 stomach: 2.0 Cell line enriched 31 RH-30: 132.6 +OCLM ENSG00000262180 Oculomedin 1 186400572-186401455 Predicted membrane proteins Evidence at transcript level Mixed Mixed epididymis: 2.4 Mixed +PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 Protocadherin gamma subfamily B, 3 5 141370264-141512979 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA008755, HPA010580, HPA035823 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Mixed Mixed endometrium: 1.5 Cell line enhanced ASC diff: 7.2;ASC TERT1: 5.9;TIME: 4.5 +CORO7 FLJ22021 ENSG00000262246 Coronin 7 16 4354542-4425705 Predicted intracellular proteins Evidence at protein level HPA041657, HPA053586 Uncertain Endometrial cancer:4.25e-4 (favourable), Cervical cancer:8.68e-4 (favourable) Expressed in all Mixed bone marrow: 24.5 Cell line enhanced RPMI-8226: 52.3 +MMP12 HME ENSG00000262406 Matrix metallopeptidase 12 11 102862736-102875034 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Liver cancer:1.42e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 54.6;urinary bladder: 28.7 tonsil: 17.3 Group enriched 11 BJ: 2.7;fHDF/TERT166: 8.5;hTEC/SVTERT24-B: 6.1 +CCER2 ENSG00000262484 Coiled-coil glutamate rich protein 2 19 38908980-38912158 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA069716 Uncertain Urothelial cancer:2.32e-4 (favourable) Mixed Tissue enhanced skin: 3.3 testis: 1.2 Mixed +RP3-422G23.4 ENSG00000262543 6 138377905-138383075 Predicted membrane proteins No evidence Not detected Not detected appendix,rectum: 0.8 Not detected +PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 Protocadherin gamma subfamily A, 4 5 141355025-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Mixed Mixed cerebral cortex: 5.7 Cell line enhanced ASC TERT1: 5.2;U-87 MG: 5.9 +LA16c-306E5.2 ENSG00000262621 16 3365099-3479550 Predicted intracellular proteins Evidence at transcript level Not detected Mixed appendix,endometrium: 1.0 Mixed +OR1D5 OR17-31 ENSG00000262628 Olfactory receptor family 1 subfamily D member 5 17 3062669-3063607 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +SPON1 f-spondin, KIAA0762 ENSG00000262655 Spondin 1 11 13962689-14267884 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA038584, HPA077546 Approved Approved Nucleus
Nucleoli
Actin filaments
Microtubule ends
Cytokinetic bridge Urothelial cancer:1.88e-4 (unfavourable), Renal cancer:3.12e-4 (favourable) Expressed in all Tissue enhanced gallbladder: 167.6 fallopian tube: 104.8 Group enriched 39 EFO-21: 209.9;RPTEC TERT1: 476.8 +RP13-1032I1.10 ENSG00000262660 17 81703371-81720539 Predicted intracellular proteins Evidence at protein level HPA022853, HPA023043, HPA023048 Approved Enhanced Mitochondria Not detected Tissue enhanced duodenum: 2.1 cerebral cortex: 1.1 Cell line enhanced MOLT-4: 14.1 +OVCA2 ENSG00000262664 Ovarian tumor suppressor candidate 2 17 2041936-2043430 Predicted intracellular proteins Evidence at protein level HPA059002 Supported Nucleoplasm
Cytosol Not detected Expressed in all gallbladder: 34.2 Expressed in all +MRPL12 MRPL7, MRPL7/L12, RPML12 ENSG00000262814 Mitochondrial ribosomal protein L12 17 81703357-81707526 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA022853, HPA023043 Supported Supported Mitochondria Lung cancer:2.35e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 57.4 Expressed in all +C19orf84 ENSG00000262874 Chromosome 19 open reading frame 84 19 51388289-51390574 Predicted intracellular proteins Evidence at transcript level HPA068082 Uncertain Tissue enhanced Tissue enriched 54 testis: 24.6 bone marrow: 0.4 Cell line enriched 7 K-562: 6.2 +FAM58A FLJ21610, MGC29729 ENSG00000262919 Family with sequence similarity 58 member A X 153587919-153600045 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050137, HPA059843 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all epididymis: 15.4 Expressed in all +GTF2I BAP-135, BTKAP1, DIWS, IB291, SPIN, TFII-I, WBSCR6 ENSG00000263001 General transcription factor IIi 7 74657667-74760692 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004595, HPA026638 Supported Enhanced Nucleoplasm Renal cancer:6.35e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 232.3 Expressed in all +ZNF234 HZF4, ZNF269 ENSG00000263002 Zinc finger protein 234 19 44141557-44160309 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001664 Approved Approved Nuclear bodies Urothelial cancer:4.34e-5 (favourable) Expressed in all Mixed parathyroid gland: 9.1 Mixed +XXbac-BPG32J3.22 ENSG00000263020 6 31666102-31673546 Predicted intracellular proteins Evidence at protein level HPA005944, HPA048307 Uncertain Not detected Tissue enriched 20 bone marrow: 6.6 cerebral cortex: 0.3 Mixed +MYZAP GCOM1, Gup, Gup1, MYOZAP ENSG00000263155 Myocardial zonula adherens protein 15 57591941-57685364 Predicted intracellular proteins Evidence at protein level HPA039827 Approved Mixed Tissue enhanced heart muscle: 388.5 placenta: 84.1 Cell line enhanced HEL: 121.1;HUVEC TERT2: 24.2;TIME: 25.5 +CTC-479C5.6 ENSG00000263201 16 68013436-68015911 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 8 placenta: 1.2;testis: 3.1 bone marrow: 0.2 Not detected +CTB-133G6.1 ENSG00000263264 19 7348943-7383385 Predicted membrane proteins Evidence at protein level HPA049151 Uncertain Mixed Tissue enhanced lymph node: 22.3;spleen: 16.5 appendix: 15.3 Cell line enhanced Daudi: 38.3;HL-60: 18.6;MOLT-4: 18.2;REH: 18.9;THP-1: 15.0;U-698: 23.8;U-937: 14.2 +PPIAL4A COAS2, PPIAL4, PPIAL4B ENSG00000263353 Peptidylprolyl isomerase A like 4A 1 120889746-120890405 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA058345 Uncertain Not detected Not detected cerebral cortex: 0.4 Mixed +LINC00675 ENSG00000263429 Long intergenic non-protein coding RNA 675 17 10794913-10804099 Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced colon: 36.9;rectum: 40.8;stomach: 44.3 duodenum,small intestine: 18.3 Cell line enriched 8 RT4: 3.2 +PPIAL4C ENSG00000263464 Peptidylprolyl isomerase A like 4C 1 149583865-149584464 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA058345 Uncertain Not detected Mixed duodenum: 3.9 Mixed +SRSF8 SFRS2B, SRP46 ENSG00000263465 Serine and arginine rich splicing factor 8 11 95067197-95071224 Predicted intracellular proteins Evidence at protein level HPA049905 Supported Supported Nucleus
Cytosol Renal cancer:9.99e-7 (favourable) Expressed in all Expressed in all thyroid gland: 41.8 Mixed +FAM72C RP5-998N21.9 ENSG00000263513 Family with sequence similarity 72 member C 1 143955364-143971965 Predicted intracellular proteins Evidence at transcript level HPA043271, HPA067321 Uncertain Approved Vesicles
Plasma membrane
Cytosol Mixed Tissue enhanced lymph node: 5.5;tonsil: 4.3 testis: 3.0 Mixed +IKBKE IKK-i, IKKE, KIAA0151 ENSG00000263528 Inhibitor of nuclear factor kappa B kinase subunit epsilon 1 206470476-206496889 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015788, CAB025983 Approved Supported Cytosol Renal cancer:5.34e-7 (unfavourable) Expressed in all Mixed lymph node: 27.4 Mixed +RP11-599B13.6 ENSG00000263620 17 8150816-8162975 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced colon: 5.2;spleen: 5.1;stomach: 4.5 adipose tissue: 3.8 Cell line enhanced HDLM-2: 28.8;HEK 293: 11.5;REH: 14.0 +MSMB IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94 ENSG00000263639 Microseminoprotein beta 10 46033307-46046269 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level CAB026357, HPA051257 Enhanced Urothelial cancer:7.19e-4 (favourable) Tissue enriched Tissue enriched 26 prostate: 15294.0 stomach: 588.5 Cell line enhanced BEWO: 24.7;NB-4: 13.6;RPMI-8226: 7.7;SH-SY5Y: 6.3;U-2197: 11.3 +LINC02210-CRHR1 ENSG00000263715 LINC02210-CRHR1 readthrough 17 45620344-45835826 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 9 cerebral cortex: 1.1 fallopian tube: 0.1 Not detected +GDF2 BMP-9, BMP9 ENSG00000263761 Growth differentiation factor 2 10 47322490-47326270 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB023357 Uncertain Not detected Tissue enriched 61 liver: 11.3 placenta,testis: 0.1 Not detected +LINC00672 ENSG00000263874 Long intergenic non-protein coding RNA 672 17 38925168-38929384 Predicted membrane proteins Evidence at transcript level Mixed Tissue enriched 6 cerebral cortex: 20.1 endometrium: 3.3 Cell line enhanced NTERA-2: 6.4 +NBPF11 NBPF24 ENSG00000263956 Neuroblastoma breakpoint family member 11 1 148102046-148152322 Predicted intracellular proteins Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA044023, HPA046971, HPA058050 Uncertain Approved Vesicles Urothelial cancer:3.20e-5 (favourable), Lung cancer:6.87e-4 (favourable) Mixed Expressed in all epididymis: 20.8 Mixed +C1orf186 FLJ16052 ENSG00000263961 Chromosome 1 open reading frame 186 1 206037231-206102459 Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced cervix, uterine: 37.8 seminal vesicle: 28.9 Cell line enriched 7 HMC-1: 1374.2 +ANXA8L1 ANXA8L2, bA145E20.2, bA301J7.3 ENSG00000264230 Annexin A8-like 1 10 46375627-46537864 Predicted intracellular proteins Evidence at protein level HPA045246, HPA047451 Approved Nucleoplasm Mixed Group enriched 7 esophagus: 199.3;skin: 460.9 urinary bladder: 44.2 Cell line enhanced HaCaT: 384.4;HBEC3-KT: 476.5;hTCEpi: 124.5;SiHa: 166.0 +NOTCH2NL N2N ENSG00000264343 Notch 2 N-terminal like 1 146146203-146229026 Predicted intracellular proteins Evidence at protein level CAB004669 Approved Not detected Expressed in all testis: 41.4 Expressed in all +DYNLL2 Dlc2, DNCL1B, MGC17810, RSPH22 ENSG00000264364 Dynein light chain LC8-type 2 17 58083415-58095536 Predicted intracellular proteins Evidence at protein level HPA039954 Uncertain Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:1.12e-12 (favourable), Pancreatic cancer:5.26e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 95.0 Expressed in all +MYH4 MYH2B, MyHC-2B, MyHC-IIb ENSG00000264424 Myosin heavy chain 4 17 10443290-10469559 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001349 Supported Tissue enriched Tissue enriched 22 skeletal muscle: 3.6 testis: 0.1 Not detected +OTUD7B CEZANNE, ZA20D1 ENSG00000264522 OTU deubiquitinase 7B 1 149937812-150010676 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027045 Supported Approved Nucleoplasm
Microtubules Melanoma:5.09e-5 (favourable), Endometrial cancer:7.47e-4 (favourable) Expressed in all Mixed parathyroid gland: 23.7 Mixed +RP13-582O9.6 ENSG00000264668 8 143247110-143276403 Predicted intracellular proteins Evidence at transcript level HPA047232, HPA056268 Uncertain Uncertain Nucleus
Nucleoli Not detected Tissue enhanced fallopian tube: 1.1 cerebral cortex: 0.7 Mixed +CH17-360D5.1 ENSG00000264717 10 47918739-47923524 Predicted membrane proteins Evidence at transcript level HPA027863 Uncertain Not detected Tissue enhanced colon: 3.0;rectum: 2.4 skin: 2.0 Cell line enriched 12 A549: 17.8 +GJA5 CX40 ENSG00000265107 Gap junction protein alpha 5 1 147756199-147773362 Disease related genes, Predicted membrane proteins Evidence at protein level CAB013080 Uncertain Expressed in all Tissue enhanced placenta: 123.0 lung: 39.9 Cell line enriched 10 SK-BR-3: 100.3 +CTD-2370N5.3 ENSG00000265118 17 31305213-31318831 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA045033 Uncertain Not detected Tissue enhanced appendix: 5.1 tonsil: 3.0 Cell line enhanced MOLT-4: 5.4;RPMI-8226: 3.7 +ANXA8 ANX8 ENSG00000265190 Annexin A8 10 47460162-47484158 Predicted intracellular proteins Evidence at protein level HPA045246, HPA047451 Approved Nucleoplasm Pancreatic cancer:2.68e-4 (unfavourable), Head and neck cancer:6.07e-4 (unfavourable) Tissue enhanced Tissue enhanced esophagus: 229.1;skin: 368.9 urinary bladder: 64.2 Cell line enhanced HaCaT: 409.1;HBEC3-KT: 486.4;hTCEpi: 269.3 +RBP3 D10S64, D10S65, D10S66, RP66 ENSG00000265203 Retinol binding protein 3 10 47348371-47357875 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA041301, HPA044239 Supported Not detected Not detected duodenum: 0.4 Not detected +RBM8A BOV-1A, BOV-1B, BOV-1C, RBM8, RBM8B, Y14, ZNRP ENSG00000265241 RNA binding motif protein 8A 1 145917714-145927678 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA018403 Supported Enhanced Nuclear speckles Prostate cancer:1.55e-4 (unfavourable) Expressed in all Expressed in all esophagus: 161.4 Expressed in all +CTD-2510F5.6 ENSG00000265303 17 59197566-59215226 Predicted intracellular proteins Evidence at transcript level Not detected Not detected endometrium,lymph node: 0.6 Cell line enhanced NB-4: 7.0;THP-1: 4.0 +TIMM23 TIM23 ENSG00000265354 Translocase of inner mitochondrial membrane 23 10 45972449-46003734 Predicted membrane proteins Evidence at protein level HPA031408 Approved Supported Mitochondria Liver cancer:2.77e-5 (unfavourable), Ovarian cancer:6.79e-4 (favourable) Expressed in all Expressed in all testis: 142.2 Expressed in all +RNF115 CL469780, ZNF364 ENSG00000265491 Ring finger protein 115 1 145738868-145824077 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019130 Approved Approved Nucleoli
Mitochondria Liver cancer:2.95e-4 (unfavourable) Expressed in all Mixed heart muscle: 16.4 Expressed in all +AP000275.65 ENSG00000265590 21 32578822-32612281 Predicted intracellular proteins Evidence at transcript level HPA019055, HPA028849 Approved Supported Not detected Mixed testis: 26.0 Mixed +RPL17 L17, rpL23 ENSG00000265681 Ribosomal protein L17 18 49488453-49492523 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043724, HPA046385 Supported Supported Endoplasmic reticulum
Cytosol Liver cancer:3.60e-5 (unfavourable) Expressed in all Expressed in all ovary: 4394.8 Expressed in all +ZNF488 FLJ32104 ENSG00000265763 Zinc finger protein 488 10 47365496-47384273 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035957, HPA035958, HPA044867 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:4.02e-7 (unfavourable) Mixed Group enriched 7 cerebral cortex: 19.0;duodenum: 22.6;placenta: 4.8;small intestine: 12.1 epididymis,skin: 2.0 Cell line enhanced HaCaT: 41.7;HDLM-2: 65.3;RT4: 30.6 +SEC22B ERS-24, sec22b, SEC22L1 ENSG00000265808 SEC22 homolog B, vesicle trafficking protein (gene/pseudogene) 1 120150898-120176515 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB079017 Approved Renal cancer:3.34e-4 (unfavourable), Ovarian cancer:4.58e-4 (favourable) Expressed in all Expressed in all epididymis: 43.3 Expressed in all +FSBP ENSG00000265817 Fibrinogen silencer binding protein 8 94372170-94436952 Predicted intracellular proteins Evidence at protein level HPA025059, HPA026509 Approved Supported Nucleus Not detected Mixed fallopian tube: 10.7 Mixed +TXNIP ARRDC6, EST01027, HHCPA78, THIF, VDUP1 ENSG00000265972 Thioredoxin interacting protein 1 145992435-145996600 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA031085, HPA053694 Approved Approved Plasma membrane
Cytosol Expressed in all Expressed in all adipose tissue: 1576.7 Cell line enhanced ASC TERT1: 662.0;HSkMC: 921.1 +SRGAP2 ARHGAP34, FNBP2, KIAA0456, SRGAP2A ENSG00000266028 SLIT-ROBO Rho GTPase activating protein 2 1 206203345-206464443 Predicted intracellular proteins Evidence at protein level HPA028191, HPA028196 Approved Supported Nucleoplasm
Cytosol Renal cancer:4.61e-7 (unfavourable), Liver cancer:9.61e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 55.9 Expressed in all +BAHCC1 BAHD2, KIAA1447 ENSG00000266074 BAH domain and coiled-coil containing 1 17 81395475-81466332 Predicted intracellular proteins Evidence at transcript level HPA023386, HPA076910 Uncertain Approved Nucleoli Pancreatic cancer:7.38e-4 (favourable) Expressed in all Mixed cerebral cortex,gallbladder: 4.8 Cell line enhanced NB-4: 68.5;REH: 30.1;SCLC-21H: 26.5 +RP11-159D12.5 ENSG00000266086 17 57989038-58005253 Predicted intracellular proteins Evidence at transcript level Not detected Mixed skin: 17.9 Expressed in all +RASSF5 Maxp1, NORE1, RAPL ENSG00000266094 Ras association domain family member 5 1 206507530-206589448 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA070480 Approved Renal cancer:1.22e-6 (unfavourable), Cervical cancer:1.46e-4 (favourable) Expressed in all Mixed spleen: 77.2 Cell line enhanced HMC-1: 80.2;Karpas-707: 138.2;RPMI-8226: 150.4 +STRADA LYK5, NY-BR-96, Stlk, STRAD ENSG00000266173 STE20-related kinase adaptor alpha 17 63682336-63741986 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA031637 Approved Supported Nucleoplasm
Cytosol Renal cancer:6.08e-7 (unfavourable), Pancreatic cancer:5.34e-5 (favourable), Urothelial cancer:6.43e-4 (favourable) Expressed in all Expressed in all testis: 67.7 Expressed in all +RP1-66C13.4 ENSG00000266202 17 27798806-27893365 Predicted intracellular proteins Evidence at transcript level HPA023051 Uncertain Not detected Tissue enhanced ovary: 1.1 cerebral cortex: 0.7 Not detected +KLF14 BTEB5 ENSG00000266265 Kruppel like factor 14 7 130731235-130734061 Predicted intracellular proteins Evidence at transcript level HPA044729 Uncertain Tissue enriched Tissue enhanced placenta: 1.2 adipose tissue: 0.7 Cell line enhanced RH-30: 1.2 +NBPF15 MGC8902, NBPF16 ENSG00000266338 Neuroblastoma breakpoint family member 15 1 144421386-144461674 Predicted intracellular proteins Evidence at protein level HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Renal cancer:4.11e-5 (unfavourable) Expressed in all Expressed in all epididymis: 25.4 Mixed +NCOA4 ARA70, DKFZp762E1112, ELE1, PTC3, RFG ENSG00000266412 Nuclear receptor coactivator 4 10 46005088-46030714 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051260, HPA065208 Uncertain Approved Nucleoli
Golgi apparatus
Cytosol Renal cancer:8.04e-6 (favourable), Glioma:2.88e-4 (favourable) Expressed in all Expressed in all duodenum: 247.1 Expressed in all +MRPS21 ENSG00000266472 Mitochondrial ribosomal protein S21 1 150293720-150308979 Predicted intracellular proteins Evidence at protein level HPA078289 Supported Mitochondria Liver cancer:2.62e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 73.9 Expressed in all +GDF10 BMP-3b ENSG00000266524 Growth differentiation factor 10 10 47300386-47313547 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA015498 Uncertain Mixed Tissue enhanced lung: 19.6 testis: 9.0 Cell line enhanced AF22: 14.6;MOLT-4: 2.6;SH-SY5Y: 6.4 +MYO15B MYO15BP ENSG00000266714 Myosin XVB 17 75588058-75626501 Predicted intracellular proteins Evidence at transcript level HPA022857, HPA023105 Approved Cytosol Urothelial cancer:6.90e-5 (favourable), Breast cancer:9.34e-4 (favourable) Expressed in all Expressed in all duodenum: 148.3 Cell line enhanced A549: 36.9;HMC-1: 21.7;THP-1: 24.6 +TBC1D29 DKFZP434O047 ENSG00000266733 TBC1 domain family member 29 17 30557112-30563493 Predicted intracellular proteins Evidence at transcript level HPA059178 Uncertain Not detected Tissue enriched 11 testis: 10.6 epididymis: 0.9 Not detected +CTD-2200P10.1 ENSG00000266826 17 58660424-58692018 Predicted intracellular proteins Evidence at protein level HPA000634, HPA001004 Uncertain Approved Microtubules Not detected Tissue enriched 33 testis: 13.5 placenta: 0.4 Not detected +RP11-618P17.4 ENSG00000266953 19 34396315-34409364 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced skeletal muscle: 3.0 stomach: 0.7 Mixed +FXYD1 PLM ENSG00000266964 FXYD domain containing ion transport regulator 1 19 35138808-35143109 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026873 Approved Nucleus
Nucleoli
Cytosol Renal cancer:7.59e-8 (unfavourable), Glioma:9.67e-4 (unfavourable) Tissue enhanced Expressed in all skeletal muscle: 469.1 Cell line enhanced ASC diff: 30.9;ASC TERT1: 9.1;HSkMC: 13.6 +AARSD1 MGC2744 ENSG00000266967 Alanyl-tRNA synthetase domain containing 1 17 42950526-42964498 Predicted intracellular proteins Evidence at protein level HPA021408, HPA022869, HPA023714 Supported Approved Nuclear membrane
Cytosol Renal cancer:1.67e-6 (unfavourable) Expressed in all Expressed in all testis: 99.4 Expressed in all +AC006538.4 ENSG00000267001 19 2717769-2740048 Predicted membrane proteins Evidence at protein level HPA058526 Uncertain Not detected Mixed testis: 3.9 Mixed +ZNF850 ZNF850P ENSG00000267041 Zinc finger protein 850 19 36714383-36772825 Predicted intracellular proteins Evidence at transcript level HPA029299 Uncertain Approved Nucleoplasm Mixed Mixed testis: 4.7 Cell line enhanced HEL: 13.4 +PTGES3L ENSG00000267060 Prostaglandin E synthase 3 like 17 42968088-42980433 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced heart muscle: 30.2;skeletal muscle: 58.7 smooth muscle: 16.3 Cell line enhanced THP-1: 17.1 +RP11-322E11.6 ENSG00000267140 18 35443871-35497940 Predicted intracellular proteins Evidence at transcript level Not detected Mixed fallopian tube: 5.3 Cell line enriched 58 HUVEC TERT2: 215.0 +CTB-54O9.9 ENSG00000267157 19 5784005-5785619 Predicted intracellular proteins Evidence at transcript level Not detected Mixed testis: 1.0 Mixed +RP11-318A15.7 ENSG00000267168 17 76732978-76738522 Predicted intracellular proteins No evidence Not detected Not detected bone marrow: 0.1 Not detected +CTC-512J12.6 ENSG00000267173 19 44329695-44401608 Predicted intracellular proteins No evidence Not detected Not detected cervix, uterine: 0.5 Not detected +CTD-2006C1.13 ENSG00000267179 19 11925075-11979290 Predicted intracellular proteins No evidence HPA047845 Uncertain Uncertain Nucleus Not detected Not detected testis: 0.5 Not detected +LCN6 ENSG00000267206 Lipocalin 6 9 136744011-136748528 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 234 epididymis: 1881.6 smooth muscle: 8.0 Group enriched 5 NB-4: 2.1;REH: 9.6 +CTD-2132N18.2 ENSG00000267221 17 42038232-42050614 Predicted membrane proteins Evidence at transcript level Renal cancer:4.24e-7 (favourable) Mixed Mixed fallopian tube: 2.6 Mixed +CTD-2132N18.3 ENSG00000267261 17 42119674-42154916 Predicted intracellular proteins Evidence at transcript level Not detected Not detected appendix: 0.8 Cell line enhanced MOLT-4: 2.9;REH: 2.3;U-87 MG: 2.2 +RP11-793H13.10 ENSG00000267281 12 53506688-53625979 Predicted intracellular proteins Evidence at transcript level HPA003384 Uncertain Approved Nucleus
Cytosol Mixed Not detected lung: 0.8 Cell line enhanced A549: 1.1 +RP11-178C3.1 ENSG00000267318 17 59940908-59973101 Predicted intracellular proteins Evidence at transcript level Not detected Mixed testis: 11.4 Cell line enhanced U-266/84: 15.4 +CTB-60B18.6 ENSG00000267335 19 49022953-49036895 Predicted intracellular proteins, Predicted secreted proteins Evidence at transcript level HPA038925 Uncertain Approved Cytosol Not detected Not detected duodenum,testis: 0.7 Cell line enhanced HMC-1: 3.7;U-251 MG: 5.2 +CTC-454I21.3 ENSG00000267360 19 37093019-37210512 Predicted intracellular proteins No evidence Not detected Not detected cerebral cortex,thyroid gland: 0.8 Not detected +UPK3BL UPLP ENSG00000267368 Uroplakin 3B-like 7 102637025-102642791 Predicted membrane proteins, Transporters Evidence at protein level HPA011403 Supported Mixed Expressed in all esophagus: 138.6 Cell line enhanced HaCaT: 109.3 +APOC4 ENSG00000267467 Apolipoprotein C4 19 44942238-44945496 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA062671 Approved Tissue enriched Tissue enriched 124 liver: 347.3 testis: 2.8 Cell line enhanced HEL: 1.5;SK-MEL-30: 2.0 +ZNF285 ZNF285A ENSG00000267508 Zinc finger protein 285 19 44382298-44401608 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046100, HPA049212 Uncertain Mixed Mixed ovary: 7.9 Mixed +S1PR2 AGR16, DFNB68, EDG5, Gpcr13, H218 ENSG00000267534 Sphingosine-1-phosphate receptor 2 19 10221435-10231272 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA014255, HPA014307 Approved Uncertain Nuclear speckles
Golgi apparatus Renal cancer:4.36e-10 (unfavourable) Expressed in all Tissue enhanced placenta: 27.0 lymph node: 13.3 Cell line enhanced Daudi: 38.8;U-698: 40.3;WM-115: 38.8 +RP5-1052I5.2 ENSG00000267561 1 86993009-87169204 Predicted intracellular proteins Evidence at protein level HPA043069, HPA043603 Approved Uncertain Mitochondria Not detected Tissue enhanced adipose tissue: 22.0 breast: 8.9 Cell line enhanced ASC TERT1: 6.6;HEL: 13.2;HMC-1: 15.7;THP-1: 8.5 +RAD51L3-RFFL ENSG00000267618 17 35011349-35121493 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced testis: 4.2 cerebral cortex: 1.6 Cell line enhanced A549: 3.6 +CGB1 ENSG00000267631 Chorionic gonadotropin beta subunit 1 19 49035610-49036895 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038925, HPA038934 Supported Approved Cytosol Not detected Not detected pancreas: 0.6 Cell line enriched 5 HMC-1: 16.3 +FDX2 FDX1L, MGC19604 ENSG00000267673 Ferredoxin 2 19 10310045-10316015 Predicted intracellular proteins Evidence at protein level HPA043986 Approved Expressed in all Expressed in all cerebral cortex: 47.4 Expressed in all +ZNF224 BMZF-2, KOX22, ZNF255, ZNF27 ENSG00000267680 Zinc finger protein 224 19 44094339-44109886 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054045 Approved Supported Nucleus
Nuclear membrane Urothelial cancer:1.53e-7 (favourable), Renal cancer:5.32e-4 (unfavourable) Expressed in all Expressed in all spleen: 35.7 Expressed in all +LUZP6 MPD6, MTPNUT ENSG00000267697 Leucine zipper protein 6 7 135927274-135927450 Predicted intracellular proteins Evidence at transcript level HPA077907 Approved Lipid droplets Not detected Not detected skeletal muscle: 0.1 Cell line enhanced MOLT-4: 8.4;SK-MEL-30: 15.0;U-2 OS: 2.4 +AC006116.20 ENSG00000267710 19 56272769-56310450 Predicted secreted proteins Evidence at transcript level Mixed Tissue enriched 699 epididymis: 120.3 ovary,thyroid gland: 0.1 Not detected +AC024592.12 ENSG00000267740 19 5866171-5903787 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA072209 Uncertain Mitochondria Not detected Mixed adrenal gland: 1.5 Mixed +CTB-102L5.4 ENSG00000267748 19 38289151-38304910 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced salivary gland: 5.5 thyroid gland: 2.9 Cell line enhanced A-431: 2.2;SK-BR-3: 3.5;U-266/84: 1.9 +SMIM22 ENSG00000267795 Small integral membrane protein 22 16 4788397-4796491 Predicted membrane proteins Evidence at transcript level HPA077331 Approved Nucleoplasm
Cytosol Mixed Mixed colon: 225.6 Group enriched 8 CAPAN-2: 277.9;RT4: 94.2;SCLC-21H: 95.4;SK-BR-3: 176.3 +LIN37 F25965, lin-37, ZK418.4 ENSG00000267796 Lin-37 DREAM MuvB core complex component 19 35748361-35754519 Predicted intracellular proteins Evidence at protein level HPA043253, HPA047809 Uncertain Supported Nucleoplasm Renal cancer:1.62e-6 (unfavourable), Pancreatic cancer:1.67e-4 (favourable) Expressed in all Expressed in all ovary: 12.5 Expressed in all +NDUFA7 B14.5a ENSG00000267855 NADH:ubiquinone oxidoreductase subunit A7 19 8308768-8321396 Predicted intracellular proteins Evidence at protein level HPA059251, HPA071866 Enhanced Supported Mitochondria Expressed in all Expressed in all heart muscle: 67.3 Expressed in all +AC011513.3 ENSG00000267881 19 41708612-41761282 Predicted secreted proteins Evidence at transcript level HPA011041 Approved Tissue enhanced Group enriched 11 colon: 41.2;esophagus: 10.3 appendix: 2.4 Not detected +CCDC177 C14orf162, PLPL ENSG00000267909 Coiled-coil domain containing 177 14 69569816-69574837 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced cerebral cortex: 2.2 epididymis: 0.6 Cell line enhanced SCLC-21H: 1.9 +CTD-2207O23.12 ENSG00000267952 19 7507052-7519622 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 5.6;skeletal muscle: 4.6 kidney: 2.9 Cell line enhanced AF22: 10.9;ASC diff: 8.4;fHDF/TERT166: 10.6;HBF TERT88: 6.7 +MAGEA9B ENSG00000267978 MAGE family member A9B X 149581653-149587453 Predicted intracellular proteins Evidence at protein level Tissue enhanced Tissue enriched 36 testis: 17.3 placenta: 0.4 Group enriched 15 RT4: 104.5;U-266/70: 42.1;U-266/84: 51.2 +SSX4 CT5.4 ENSG00000268009 SSX family member 4 X 48383516-48393347 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level HPA045683 Approved Approved Nucleus
Nucleoli Not detected Tissue enriched 15 testis: 3.8 fallopian tube: 0.2 Group enriched 8 BEWO: 2.1;Karpas-707: 3.9;U-266/70: 2.4;U-266/84: 4.3 +CTD-2575K13.6 ENSG00000268041 19 41907705-41928516 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced lymph node: 3.4 appendix: 1.7 Group enriched 5 Daudi: 4.5;HMC-1: 3.9;REH: 1.2;U-2 OS: 2.8;U-266/70: 1.8;U-698: 2.6;U-937: 2.1 +NBPF12 COAS1, KIAA1245 ENSG00000268043 Neuroblastoma breakpoint family member 12 1 146938744-146996202 Predicted intracellular proteins Evidence at protein level HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Pancreatic cancer:9.01e-7 (favourable), Urothelial cancer:2.47e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 19.8 Expressed in all +AC104534.3 ENSG00000268083 19 38817471-38840178 Predicted intracellular proteins Evidence at protein level HPA002907, HPA051748 Uncertain Not detected Not detected lung: 0.9 Cell line enhanced NB-4: 19.4 +GABRQ THETA ENSG00000268089 Gamma-aminobutyric acid type A receptor theta subunit X 152638183-152657534 FDA approved drug targets, Predicted membrane proteins Evidence at transcript level Tissue enhanced Tissue enhanced cerebral cortex: 6.6;cervix, uterine: 12.9 adrenal gland: 3.0 Group enriched 7 HeLa: 8.2;SiHa: 12.7;U-87 MG: 37.4 +SLC6A14 ENSG00000268104 Solute carrier family 6 member 14 X 116436622-116461458 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at transcript level HPA003193 Uncertain Approved Vesicles Pancreatic cancer:9.74e-4 (unfavourable) Mixed Tissue enhanced cervix, uterine: 11.0;lung: 23.9 breast: 9.1 Cell line enhanced HeLa: 1.0;Hep G2: 2.3 +AC003002.4 ENSG00000268133 19 57363566-57398584 Predicted intracellular proteins No evidence Not detected Not detected adipose tissue,appendix: 0.2 Not detected +AC004076.9 ENSG00000268163 19 57437970-57477536 Predicted intracellular proteins Evidence at transcript level Not detected Mixed cerebral cortex: 1.0 Not detected +SMIM17 ENSG00000268182 Small integral membrane protein 17 19 56643145-56655766 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA071857, HPA071861 Enhanced Approved Vesicles Mixed Tissue enhanced cerebral cortex: 8.7 epididymis: 2.0 Cell line enhanced AF22: 2.3;HEK 293: 2.1;SCLC-21H: 2.5 +OPN1MW CBBM, CBD, COD5, GCP, OPN1MW1 ENSG00000268221 Opsin 1, medium wave sensitive X 154182596-154196135 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Not detected Not detected appendix: 0.1 Not detected +ARL14EPL ENSG00000268223 ADP ribosylation factor like GTPase 14 effector protein like 5 116032324-116060118 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.2 Cell line enriched 12 HDLM-2: 48.6 +SCGB1C2 ENSG00000268320 Secretoglobin family 1C member 2 17 137526-139067 Predicted secreted proteins No evidence Tissue enhanced Not detected appendix,testis: 0.2 Not detected +FAM156A PRO0659, TMEM29 ENSG00000268350 Family with sequence similarity 156 member A X 52926402-52995472 Predicted intracellular proteins Evidence at protein level HPA056640, HPA056643 Approved Not detected Expressed in all skin: 63.1 Expressed in all +L34079.2 ENSG00000268361 19 43554692-43593036 Predicted intracellular proteins No evidence Not detected Not detected parathyroid gland: 0.5 Not detected +AC011530.4 ENSG00000268434 19 45779437-45785973 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced epididymis: 1.0 appendix: 0.9 Not detected +SSX2B CT5.2b ENSG00000268447 SSX family member 2B X 52751132-52790305 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045683 Supported Approved Nucleus
Nucleoli Not detected Tissue enriched 23 testis: 14.9 thyroid gland: 0.6 Cell line enhanced HMC-1: 1.7;PC-3: 1.8;U-2197: 1.1 +CTC-273B12.7 ENSG00000268465 19 48465837-48472431 Predicted intracellular proteins Evidence at transcript level HPA060662 Not detected Tissue enhanced colon: 1.1;endometrium: 1.3;testis: 2.8 small intestine: 0.6 Cell line enhanced AN3-CA: 1.0;LHCN-M2: 1.1;U-698: 1.2 +AC018755.18 ENSG00000268500 19 51612091-51646889 Predicted membrane proteins Evidence at transcript level HPA009085 Approved Not detected Tissue enhanced appendix: 10.0;bone marrow: 17.4 spleen: 5.5 Group enriched 14 HMC-1: 68.6;U-937: 25.7 +AC004076.7 ENSG00000268533 19 57394183-57438457 Predicted intracellular proteins Evidence at transcript level Not detected Mixed skin: 8.9 Cell line enhanced SCLC-21H: 6.0 +MAGEA2 CT1.2, MAGE2, MAGEA2A ENSG00000268606 MAGE family member A2 X 152749863-152753884 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 54 testis: 6.9 cerebral cortex: 0.1 Cell line enhanced HMC-1: 40.2;K-562: 58.6;SH-SY5Y: 52.5;SK-BR-3: 36.4;U-266/70: 92.1;U-266/84: 61.1 +TEX13A ENSG00000268629 Testis expressed 13A X 105218929-105220674 Predicted intracellular proteins Evidence at protein level HPA072257 Enhanced Not detected Tissue enriched 79 testis: 7.9 all non-specific tissues: 0.0 Not detected +AC006486.9 ENSG00000268643 19 42234583-42255132 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 7.8 endometrium: 5.1 Cell line enhanced RT4: 21.6 +CTAG1A ESO1, LAGE2A ENSG00000268651 Cancer/testis antigen 1A X 154585143-154586821 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB013061 Enhanced Not detected Tissue enriched 37 testis: 4.6 spleen: 0.1 Group enriched 942 U-266/70: 511.5;U-266/84: 120.6 +CTB-60B18.10 ENSG00000268655 19 49017496-49020523 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced pancreas: 1.7;testis: 1.3 stomach: 0.3 Cell line enhanced HEK 293: 1.1 +FAM231D ENSG00000268674 Family with sequence similarity 231 member D Unmapped 35407-35916 Predicted intracellular proteins No evidence HPA043267, HPA043292 Uncertain Not detected all non-specific tissues: 0.0 Not detected +ARL14EPL ENSG00000268714 ADP ribosylation factor like GTPase 14 effector protein like 5 116022391-116059130 Predicted intracellular proteins Evidence at transcript level Not detected Not detected testis: 0.6 Cell line enriched 54 HDLM-2: 119.0 +HSFX2 ENSG00000268738 Heat shock transcription factor family, X-linked 2 X 149592515-149594716 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063040 Supported Not detected Tissue enriched 8 testis: 9.3 seminal vesicle: 1.1 Not detected +CTD-2583A14.10 ENSG00000268750 19 57819719-57858941 Predicted intracellular proteins Evidence at transcript level HPA056213 Uncertain Not detected Mixed duodenum: 4.9 Cell line enhanced HEK 293: 25.5 +CTC-429P9.4 ENSG00000268790 19 16577642-16660115 Predicted intracellular proteins Evidence at transcript level Not detected Mixed endometrium: 1.3 Cell line enhanced T-47d: 3.0 +CTD-2207O23.3 ENSG00000268861 19 7382834-7472477 Predicted intracellular proteins Evidence at protein level HPA042689, HPA071867 Supported Uncertain Cytosol Not detected Tissue enhanced lymph node: 17.2 spleen: 11.9 Cell line enhanced Daudi: 18.2;MOLT-4: 13.4;REH: 12.3;THP-1: 12.9 +CTD-3105H18.16 ENSG00000268870 19 12391949-12441082 Predicted intracellular proteins Evidence at protein level HPA003150, HPA018683 Uncertain Uncertain Nucleoplasm
Microtubule organizing center Not detected Not detected breast,placenta: 0.6 Cell line enhanced RH-30: 4.0 +CSAG2 CSAG3B, CT24.2, TRAG3 ENSG00000268902 CSAG family member 2 X 152708261-152714549 Predicted intracellular proteins Evidence at transcript level HPA078264 Approved Vesicles Mixed Not detected lymph node,testis: 0.9 Cell line enhanced HMC-1: 13.5;SK-BR-3: 4.8;U-266/70: 3.9;U-266/84: 4.7 +CSAG3 CSAG3A ENSG00000268916 CSAG family member 3 X 152753921-152760222 Predicted intracellular proteins Evidence at transcript level HPA078264 Approved Vesicles Mixed Group enriched 10 lymph node: 1.7;skin: 1.2;spleen: 1.9;testis: 4.2 adipose tissue,lung,placenta: 0.2 Cell line enhanced HDLM-2: 23.7;HMC-1: 22.9;SH-SY5Y: 35.8;SK-BR-3: 23.6;U-2 OS: 25.4;U-266/70: 61.5;U-266/84: 30.6 +CT45A1 CT45-1, CT45.1 ENSG00000268940 Cancer/testis antigen family 45 member A1 X 135713453-135723539 Predicted intracellular proteins Evidence at protein level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Mixed Tissue enriched 42 testis: 12.5 cerebral cortex,lung: 0.2 Group enriched 6 HMC-1: 202.8;Karpas-707: 77.5 +ERVV-2 ENSG00000268964 Endogenous retrovirus group V member 2 19 53044738-53051076 Predicted membrane proteins Evidence at transcript level Mixed Tissue enriched 101 placenta: 13.6 kidney,testis,thyroid gland: 0.1 Group enriched 5 BEWO: 18.5;T-47d: 5.1 +SPANXN2 CT11.7, SPANX-N2 ENSG00000268988 SPANX family member N2 X 143711955-143721423 Predicted intracellular proteins Evidence at protein level HPA045652 Approved Nucleus
Nucleoli fibrillar center Not detected Tissue enriched 26 testis: 2.5 all non-specific tissues: 0.0 Not detected +FAM231B ENSG00000268991 Family with sequence similarity 231 member B 1 16539066-16539575 Predicted intracellular proteins No evidence HPA043267, HPA043292 Uncertain Not detected Not detected testis: 0.3 Not detected +FAM236B ENSG00000268994 Family with sequence similarity 236 member B X 72781865-72782660 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 50 testis: 115.3 thyroid gland: 2.3 Not detected +AC003006.7 ENSG00000269026 19 57682045-57753575 Predicted intracellular proteins Evidence at transcript level HPA068553 Approved Nucleus Not detected Not detected seminal vesicle: 0.2 Cell line enhanced HL-60: 1.0;U-266/84: 1.4 +MTRNR2L12 ENSG00000269028 MT-RNR2-like 12 3 96617188-96618236 Predicted intracellular proteins Evidence at transcript level Expressed in all Expressed in all heart muscle: 15284.0 Expressed in all +CTD-2521M24.10 ENSG00000269035 19 17436611-17460804 Predicted membrane proteins No evidence HPA041580, HPA042010 Uncertain Uncertain Nuclear membrane Not detected Not detected all non-specific tissues: 0.0 Not detected +CALR3 CRT2, CT93, FLJ25355, MGC26577 ENSG00000269058 Calreticulin 3 19 16479057-16496192 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB025749, HPA043355, HPA048460 Enhanced Not detected Tissue enriched 93 testis: 98.8 epididymis: 1.0 Not detected +ZNF728 ENSG00000269067 Zinc finger protein 728 19 22975468-23003176 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 5 testis: 18.2 thyroid gland: 3.6 Cell line enriched 5 U-266/84: 2.1 +AC010646.3 ENSG00000269095 19 17235940-17255448 Predicted intracellular proteins Evidence at transcript level Not detected Mixed epididymis: 1.4 Cell line enhanced BEWO: 5.8;EFO-21: 1.6 +CT45A3 CT45-3, CT45-4, CT45.3, CT45.4, CT45A4 ENSG00000269096 Cancer/testis antigen family 45 member A3 X 135759846-135768191 Predicted intracellular proteins Evidence at protein level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Not detected Tissue enriched 15 testis: 20.5 lung: 1.3 Group enriched 6 HMC-1: 108.1;T-47d: 68.5;U-266/84: 279.7 +TRABD2B TIKI2 ENSG00000269113 TraB domain containing 2B 1 47760528-47996895 Predicted secreted proteins Evidence at protein level HPA045817 Approved Tissue enriched Tissue enhanced kidney: 7.7 seminal vesicle: 4.8 Group enriched 5 HeLa: 4.4;U-2197: 12.9 +FBXO17 FBG4, Fbx17, FBXO26, FLJ11798, FLJ25205, MGC9379 ENSG00000269190 F-box protein 17 19 38941401-38975910 Predicted intracellular proteins Evidence at protein level Glioma:2.10e-4 (unfavourable), Endometrial cancer:5.67e-4 (unfavourable), Stomach cancer:5.91e-4 (unfavourable) Mixed Mixed kidney: 14.4 Mixed +RP11-722G7.1 ENSG00000269226 X 104063871-104076212 Predicted intracellular proteins Evidence at transcript level Not detected Mixed ovary: 7.6 Cell line enhanced AF22: 10.6;AN3-CA: 9.4 +MAGIX FLJ21687, JM10, PDZX ENSG00000269313 MAGI family member, X-linked X 49162564-49168483 Predicted intracellular proteins Evidence at transcript level HPA035302 Uncertain Renal cancer:6.91e-9 (favourable), Urothelial cancer:2.10e-4 (favourable) Mixed Mixed parathyroid gland: 5.7 Cell line enhanced RT4: 10.2 +IKBKG FIP-3, FIP3, Fip3p, IKK-gamma, IP1, IP2, NEMO, ZC2HC9 ENSG00000269335 Inhibitor of nuclear factor kappa B kinase subunit gamma X 154541199-154565046 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA000426, CAB010373 Uncertain Enhanced Cytosol Expressed in all Expressed in all spleen: 37.2 Expressed in all +ZNF587B ENSG00000269343 Zinc finger protein 587B 19 57819741-57846238 Predicted intracellular proteins Evidence at protein level HPA043800, HPA053762, HPA072145 Uncertain Uncertain Nucleus Prostate cancer:1.33e-4 (unfavourable), Melanoma:1.37e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 11.2 Expressed in all +SPIB SPI-B ENSG00000269404 Spi-B transcription factor 19 50418938-50431313 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018523 Uncertain Head and neck cancer:2.14e-5 (favourable), Breast cancer:4.76e-5 (favourable) Mixed Tissue enhanced appendix: 53.9;lymph node: 103.3;tonsil: 91.1 spleen: 39.2 Group enriched 10 Daudi: 119.1;HDLM-2: 99.4;Karpas-707: 37.4;U-698: 159.1 +NXF2 CT39, TAPL-2 ENSG00000269405 Nuclear RNA export factor 2 X 102247161-102326719 Predicted intracellular proteins Evidence at protein level HPA002079 Uncertain Not detected Group enriched 21 epididymis: 18.6;testis: 23.3 fallopian tube: 0.9 Cell line enriched 38 U-266/84: 24.8 +OPN1MW3 ENSG00000269433 Opsin 1, medium wave sensitive 3 X 154257538-154271805 Predicted membrane proteins No evidence Not detected Not detected skin: 0.1 Not detected +NXF2B bA353J17.1 ENSG00000269437 Nuclear RNA export factor 2B X 102360395-102463274 Predicted intracellular proteins Evidence at protein level HPA002079 Uncertain Not detected Group enriched 6 epididymis: 19.1;testis: 4.9 fallopian tube: 2.1 Cell line enriched 30 U-266/84: 25.0 +DMRTC1 ENSG00000269502 DMRT like family C1 X 72872025-72943814 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA046874, HPA046992 Uncertain Not detected Tissue enhanced cerebral cortex: 2.3 fallopian tube,thyroid gland: 1.3 Not detected +ERVV-1 ENVV1, FLJ32214, HERV-V1 ENSG00000269526 Endogenous retrovirus group V member 1 19 53013921-53016122 Predicted membrane proteins Evidence at transcript level Mixed Tissue enriched 68 placenta: 22.1 prostate,urinary bladder: 0.3 Cell line enriched 8 BEWO: 7.4 +AC003002.6 ENSG00000269533 19 57389884-57419994 Predicted intracellular proteins Evidence at transcript level Not detected Not detected appendix,fallopian tube,testis: 0.2 Cell line enhanced CACO-2: 1.1;HEL: 1.1;PC-3: 1.6 +CTC-360G5.8 ENSG00000269547 19 38915404-38949855 Predicted intracellular proteins Evidence at protein level HPA052730, HPA056957 Uncertain Not detected Mixed ovary: 1.1 Cell line enhanced A-431: 1.5;A549: 2.1;T-47d: 1.9;U-251 MG: 2.4 +TMEM185A CXorf13, FAM11A, FRAXF ENSG00000269556 Transmembrane protein 185A X 149596556-149631912 Predicted membrane proteins Evidence at protein level HPA048295, HPA071744 Uncertain Approved Endoplasmic reticulum Expressed in all Expressed in all ovary: 36.4 Expressed in all +CT45A10 ENSG00000269586 Cancer/testis antigen family 45 member A10 X 135881063-135889086 Predicted intracellular proteins Evidence at protein level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Mixed Tissue enriched 23 testis: 16.5 cerebral cortex: 0.7 Cell line enhanced AN3-CA: 78.6;K-562: 23.7;Karpas-707: 67.5;U-266/84: 58.7 +CTD-2192J16.24 ENSG00000269590 19 12664828-12669397 Predicted intracellular proteins Evidence at protein level HPA065685 Uncertain Approved Nuclear membrane
Endoplasmic reticulum Not detected Tissue enhanced lymph node: 1.9 cerebral cortex,duodenum: 1.3 Cell line enhanced MCF7: 8.8;RT4: 4.7 +ZIM2 ZNF656 ENSG00000269699 Zinc finger imprinted 2 19 56774552-56840729 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071856 Approved Nuclear speckles
Cytosol Not detected Group enriched 7 adrenal gland: 5.8;cerebral cortex: 5.1;ovary: 9.9;placenta: 6.8;testis: 7.7 endometrium: 1.0 Cell line enhanced BEWO: 4.7;Hep G2: 4.0;NTERA-2: 1.6;RH-30: 1.6;U-2 OS: 1.2 +CTD-3214H19.16 ENSG00000269711 19 7678501-7682854 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced bone marrow: 14.1;lung: 11.8 duodenum: 7.7 Cell line enhanced EFO-21: 12.1;HMC-1: 18.1;NB-4: 7.8;THP-1: 22.2;U-937: 19.1 +NBPF9 AE01 ENSG00000269713 Neuroblastoma breakpoint family member 9 1 149054027-149103561 Predicted intracellular proteins Evidence at protein level HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Mixed Expressed in all thyroid gland: 23.1 Expressed in all +CTD-2521M24.13 ENSG00000269720 19 17390509-17394158 Predicted secreted proteins No evidence Mixed Not detected ovary,placenta: 0.4 Not detected +SLC25A53 MCART6 ENSG00000269743 Solute carrier family 25 member 53 X 104099214-104157027 Predicted membrane proteins Evidence at protein level HPA034959 Uncertain Mixed Mixed cerebral cortex: 2.5 Cell line enhanced Daudi: 4.3;Karpas-707: 10.0 +SSX4B OTTHUMT00000056510 ENSG00000269791 SSX family member 4B X 48402078-48411910 Predicted intracellular proteins Evidence at transcript level HPA045683 Approved Approved Nucleus
Nucleoli Not detected Tissue enriched 15 testis: 3.8 fallopian tube: 0.2 Group enriched 8 BEWO: 2.1;Karpas-707: 3.9;U-266/70: 2.4;U-266/84: 4.3 +RNF225 ENSG00000269855 Ring finger protein 225 19 58396090-58397079 Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced esophagus: 2.0;skin: 1.7 prostate: 0.6 Not detected +EGLN2 HIFPH1, PHD1 ENSG00000269858 Egl-9 family hypoxia inducible factor 2 19 40798996-40808433 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056649 Supported Nucleoplasm Cervical cancer:2.88e-4 (favourable), Pancreatic cancer:4.81e-4 (favourable) Expressed in all Expressed in all testis: 205.1 Expressed in all +AC004754.3 ENSG00000269881 16 249547-269943 Predicted membrane proteins Evidence at transcript level HPA011651, HPA071871 Uncertain Uncertain Nucleoplasm
Mitochondria Not detected Group enriched 5 duodenum: 14.2;small intestine: 7.8 testis: 2.0 Cell line enhanced EFO-21: 1.5 +COMMD3-BMI1 ENSG00000269897 COMMD3-BMI1 readthrough 10 22316388-22329542 Predicted intracellular proteins Evidence at protein level HPA030471, HPA030472, HPA036584 Uncertain Approved Nucleus
Nucleoli
Nuclear bodies
Cytosol Not detected Tissue enhanced testis: 10.2 seminal vesicle: 4.0 Mixed +C7orf55-LUC7L2 ENSG00000269955 C7orf55-LUC7L2 readthrough 7 139341360-139422599 Predicted intracellular proteins Evidence at protein level HPA045663, HPA051631 Approved Approved Nucleus Not detected Expressed in all skeletal muscle: 21.1 Expressed in all +MEI4 ENSG00000269964 Meiotic double-stranded break formation protein 4 6 77690658-77926974 Predicted secreted proteins Evidence at transcript level Tissue enhanced Tissue enhanced kidney: 4.5;testis: 4.8;thyroid gland: 3.9 adrenal gland: 0.9 Not detected +ZNF559-ZNF177 ENSG00000270011 ZNF559-ZNF177 readthrough 19 9324174-9382617 Predicted intracellular proteins Evidence at transcript level HPA003141 Uncertain Not detected Mixed testis: 10.2 Cell line enhanced HEK 293: 6.1 +C8orf44-SGK3 ENSG00000270024 C8orf44-SGK3 readthrough 8 66667596-66860472 Predicted intracellular proteins Evidence at transcript level HPA006699, HPA027146 Uncertain Approved Nucleoplasm
Vesicles Not detected Not detected cervix, uterine: 0.9 Cell line enhanced fHDF/TERT166: 1.3 +MINOS1-NBL1 ENSG00000270136 MINOS1-NBL1 readthrough 1 19596979-19658056 Predicted secreted proteins Evidence at transcript level HPA007394 Uncertain Not detected Tissue enhanced duodenum: 16.2;small intestine: 17.2 adipose tissue: 13.7 Cell line enhanced A-431: 25.2;BJ: 49.3;EFO-21: 25.9;HDLM-2: 32.5 +LA16c-380H5.3 ENSG00000270168 16 2988256-3002016 Predicted secreted proteins Evidence at transcript level Mixed Tissue enriched 7 skin: 4.8 lung: 0.7 Cell line enhanced HaCaT: 3.6;hTCEpi: 2.2;SCLC-21H: 3.6 +NCBP2-AS2 ENSG00000270170 NCBP2 antisense RNA 2 (head to head) 3 196942623-196943540 Predicted secreted proteins Evidence at protein level Renal cancer:8.92e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 28.6 Expressed in all +BIVM-ERCC5 ENSG00000270181 BIVM-ERCC5 readthrough 13 102799110-102876001 Predicted intracellular proteins Evidence at protein level HPA045845, HPA050126, HPA050374 Uncertain Supported Nucleoplasm Not detected Expressed in all thyroid gland: 22.8 Mixed +MTRNR2L11 ENSG00000270188 MT-RNR2-like 11 1 237943724-237945275 Predicted secreted proteins Evidence at transcript level Not detected Expressed in all skeletal muscle: 113.4 Expressed in all +RP11-514P8.7 ENSG00000270249 7 102541501-102592444 Predicted intracellular proteins Evidence at transcript level HPA046970 Uncertain Uncertain Nucleoplasm Not detected Tissue enhanced parathyroid gland: 3.9 duodenum,epididymis: 1.0 Not detected +HIST2H4B H4/o ENSG00000270276 Histone cluster 2 H4 family member b 1 149854045-149861210 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Not detected Mixed fallopian tube: 4.6 Cell line enhanced SCLC-21H: 5.7;SiHa: 7.9;U-266/70: 6.6;U-266/84: 5.4 +RP5-850E9.3 ENSG00000270299 20 646626-675800 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 2.7;testis: 1.7 endometrium: 1.5 Cell line enhanced Hep G2: 9.9;SK-BR-3: 6.5 +CH17-385C13.3 ENSG00000270339 1 146344131-146344790 Predicted intracellular proteins No evidence HPA058345 Uncertain Not detected Not detected spleen: 0.2 Not detected +HEATR9 C17orf66, FLJ32830 ENSG00000270379 HEAT repeat containing 9 17 35854946-35868891 Predicted intracellular proteins Evidence at transcript level HPA023129 Uncertain Not detected Tissue enriched 34 testis: 10.0 spleen: 0.2 Not detected +MTRNR2L13 ENSG00000270394 MT-RNR2-like 13 4 116298876-116300320 Predicted intracellular proteins Evidence at transcript level Not detected Not detected adrenal gland: 0.8 Cell line enhanced HeLa: 2.2;Hep G2: 1.2 +PRAMEF5 PRAMEF23, PRAMEF5L ENSG00000270601 PRAME family member 5 1 13254212-13263314 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +URGCP-MRPS24 ENSG00000270617 URGCP-MRPS24 readthrough 7 43866558-43906589 Predicted intracellular proteins Evidence at transcript level Not detected Mixed cervix, uterine: 1.3 Cell line enhanced SCLC-21H: 3.9 +NBPF14 DJ328E19.C1.1 ENSG00000270629 Neuroblastoma breakpoint family member 14 1 148531385-148679751 Predicted intracellular proteins Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Uncertain Approved Vesicles Mixed Expressed in all skin: 66.5 Mixed +TAF15 hTAFII68, Npl3, RBP56, TAF2N ENSG00000270647 TATA-box binding protein associated factor 15 17 35713791-35864615 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052059, HPA063647 Enhanced Enhanced Nucleoplasm Expressed in all Expressed in all lymph node: 61.1 Expressed in all +MTRNR2L6 ENSG00000270672 MT-RNR2-like 6 7 142666272-142667718 Predicted intracellular proteins Evidence at transcript level Mixed Expressed in all skeletal muscle: 131.7 Cell line enhanced HeLa: 101.5;Hep G2: 93.3 +HSPE1-MOB4 ENSG00000270757 HSPE1-MOB4 readthrough 2 197500413-197550726 Predicted intracellular proteins Evidence at protein level HPA038755, HPA044125, HPA048272 Approved Not detected Mixed adrenal gland: 32.7 Expressed in all +GAS2L2 GAR17 ENSG00000270765 Growth arrest specific 2 like 2 17 35744511-35752878 Predicted intracellular proteins Evidence at protein level HPA044370 Enhanced Endometrial cancer:7.00e-4 (favourable) Tissue enhanced Tissue enriched 11 fallopian tube: 28.2 epididymis,lung: 2.6 Cell line enhanced HaCaT: 1.4 +RPS10-NUDT3 ENSG00000270800 RPS10-NUDT3 readthrough 6 34284887-34426071 Predicted intracellular proteins Evidence at protein level HPA047027, HPA047268, HPA048084, HPA055953 Uncertain Approved Cytosol Not detected Mixed testis: 11.1 Expressed in all +C17orf50 ENSG00000270806 Chromosome 17 open reading frame 50 17 35760897-35765079 Predicted intracellular proteins Evidence at protein level HPA043184, HPA063464 Supported Nucleoplasm Not detected Tissue enriched 59 testis: 38.9 fallopian tube: 0.6 Cell line enriched 5 HaCaT: 4.6 +HIST2H4A H4/n, H4F2, H4FN, HIST2H4 ENSG00000270882 Histone cluster 2 H4 family member a 1 149832659-149839767 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Not detected Mixed prostate: 13.8 Cell line enhanced SiHa: 65.9;U-2 OS: 56.3 +RASL10B RRP17, VTS58635 ENSG00000270885 RAS like family 10 member B 17 35731649-35743521 Predicted intracellular proteins Evidence at protein level HPA046842, HPA057092 Enhanced Approved Vesicles Endometrial cancer:6.38e-6 (unfavourable) Tissue enhanced Tissue enhanced adipose tissue: 16.0;seminal vesicle: 21.0 skeletal muscle: 11.1 Cell line enhanced HAP1: 25.2;HHSteC: 22.5;NTERA-2: 41.3 +GPR75-ASB3 ENSG00000270898 GPR75-ASB3 readthrough 2 53670293-53860160 Predicted intracellular proteins Evidence at transcript level HPA003940 Uncertain Not detected Tissue enhanced cerebral cortex: 1.0 spleen: 0.3 Cell line enhanced K-562: 1.3 +CT45A9 ENSG00000270946 Cancer/testis antigen family 45 member A9 X 135863776-135871812 Predicted intracellular proteins Evidence at protein level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Not detected Tissue enriched 13 testis: 1.2 all non-specific tissues: 0.0 Cell line enriched 8 HMC-1: 113.9 +CTAGE15 CTAGE15P ENSG00000271079 CTAGE family member 15 7 143571801-143574387 Predicted membrane proteins Evidence at protein level HPA000387, HPA000922 Uncertain Not detected Tissue enhanced testis: 7.3 thyroid gland: 1.6 Cell line enhanced A-431: 2.8;RT4: 2.1;SiHa: 2.8;SK-BR-3: 1.8 +TMEM56-RWDD3 ENSG00000271092 TMEM56-RWDD3 readthrough 1 95117923-95247225 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Mixed Mixed thyroid gland: 5.2 Cell line enhanced RH-30: 11.5 +AC240274.1 ENSG00000271254 Unmapped 4612-29626 Predicted intracellular proteins Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Uncertain Approved Vesicles Expressed in all testis: 73.9 Expressed in all +UGT2A2 ENSG00000271271 UDP glucuronosyltransferase family 2 member A2 4 69589309-69639642 Enzymes, Predicted membrane proteins Evidence at protein level HPA045108 Uncertain Not detected Not detected cervix, uterine,skin: 0.2 Not detected +SRXN1 C20orf139, dJ850E9.2, Npn3, SRX1, YKL086W ENSG00000271303 Sulfiredoxin 1 20 646615-653370 Enzymes, Predicted intracellular proteins Evidence at protein level Liver cancer:6.22e-5 (unfavourable) Mixed Expressed in all adrenal gland: 44.5 Mixed +CTAGE6 CTAGE6P, MGC41943 ENSG00000271321 CTAGE family member 6 7 143755089-143757696 Predicted membrane proteins Evidence at protein level HPA000387, HPA000922 Uncertain Not detected Tissue enriched 38 testis: 9.9 skin: 0.2 Not detected +NBPF19 ENSG00000271383 Neuroblastoma breakpoint family member 19 1 149390623-149556361 Predicted intracellular proteins Evidence at protein level HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Uncertain Approved Vesicles Mixed Expressed in all skin: 79.4 Expressed in all +NBPF10 AG1 ENSG00000271425 Neuroblastoma breakpoint family member 10 1 146064699-146144804 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Not detected Mixed skin: 8.1 Mixed +MMP28 EPILYSIN, MM28, MMP-25, MMP-28 ENSG00000271447 Matrix metallopeptidase 28 17 35756249-35795707 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Pancreatic cancer:6.28e-6 (unfavourable) Mixed Tissue enhanced testis: 6.5 adipose tissue: 4.2 Cell line enriched 9 HaCaT: 32.1 +CT45A2 CT45-2, CT45.2 ENSG00000271449 Cancer/testis antigen family 45 member A2 X 135811668-135820012 Predicted intracellular proteins Evidence at protein level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Not detected Tissue enriched 14 testis: 1.4 all non-specific tissues: 0.0 Group enriched 5 AN3-CA: 10.0;HMC-1: 43.4 +CCL5 D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228 ENSG00000271503 C-C motif chemokine ligand 5 17 35871491-35880793 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Renal cancer:3.61e-7 (unfavourable), Endometrial cancer:1.34e-5 (favourable), Melanoma:2.42e-4 (favourable) Expressed in all Tissue enhanced spleen: 80.5 lymph node: 68.5 Group enriched 7 HL-60: 31.8;NB-4: 158.3;THP-1: 39.1;U-937: 41.8 +PPIAL4E ENSG00000271567 Peptidylprolyl isomerase A like 4E 1 144372875-144373659 Enzymes, Predicted intracellular proteins No evidence HPA058345 Uncertain Not detected Not detected bone marrow: 0.3 Not detected +LIX1L MGC46719 ENSG00000271601 Limb and CNS expressed 1 like 1 145933423-145958001 Predicted intracellular proteins Evidence at protein level HPA063598 Approved Cytosol Renal cancer:3.19e-5 (unfavourable), Liver cancer:1.61e-4 (unfavourable), Urothelial cancer:5.27e-4 (unfavourable) Expressed in all Expressed in all ovary: 45.8 Mixed +MILR1 Allergin-1, C17orf60, MCA-32 ENSG00000271605 Mast cell immunoglobulin like receptor 1 17 64449037-64468643 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014347 Enhanced Renal cancer:5.07e-6 (unfavourable) Expressed in all Mixed appendix: 41.7 Cell line enhanced CAPAN-2: 114.8;Daudi: 46.7;REH: 47.7;U-698: 47.8 +RP11-426L16.10 ENSG00000271810 1 112702614-112711433 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced testis: 8.4 parathyroid gland: 3.5 Cell line enhanced WM-115: 5.1 +AC009014.3 ENSG00000271824 5 136191468-136193134 Predicted membrane proteins Evidence at transcript level Liver cancer:1.63e-4 (favourable), Pancreatic cancer:6.13e-4 (favourable) Tissue enhanced Tissue enhanced duodenum: 13.2;kidney: 22.7 small intestine: 6.8 Cell line enhanced SCLC-21H: 2.0 +ANKRD34A ANKRD34 ENSG00000272031 Ankyrin repeat domain 34A 1 145959442-145964582 Predicted intracellular proteins Evidence at protein level HPA029642, HPA029643 Uncertain Enhanced Cytosol Mixed Tissue enriched 8 cerebral cortex: 12.7 appendix,parathyroid gland: 1.6 Mixed +GTF2H5 bA120J8.2, C6orf175, FLJ30544, TFB5, TFIIH, TTD, TTD-A, TTDA ENSG00000272047 General transcription factor IIH subunit 5 6 158168352-158199344 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:6.11e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 11.1 Expressed in all +XXcos-LUCA11.5 ENSG00000272104 3 50350892-50367923 Predicted intracellular proteins Evidence at protein level HPA042817 Uncertain Not detected Mixed small intestine: 6.9 Cell line enhanced HMC-1: 7.9;Karpas-707: 7.6 +HIST2H2AA4 H2A/r ENSG00000272196 Histone cluster 2 H2A family member a4 1 149851061-149851624 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Tissue enhanced Tissue enhanced testis: 88.9 prostate: 32.5 Cell line enhanced SiHa: 124.1;U-266/70: 217.3;U-266/84: 190.5 +RP11-215A19.2 ENSG00000272297 4 186426546-186555328 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 16 testis: 54.0 prostate: 3.3 Group enriched 5 A-431: 2.2;T-47d: 1.2 +NUDT3 DIPP ENSG00000272325 Nudix hydrolase 3 6 34279679-34392674 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047027, HPA055953 Uncertain Approved Cytosol Cervical cancer:5.29e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 77.5 Expressed in all +KMT2B CXXC10, HRX2, KIAA0304, MLL1B, MLL2, MLL4, TRX2, WBP7 ENSG00000272333 Lysine methyltransferase 2B 19 35718019-35738878 Cancer-related genes, Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006487 Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 28.8 Expressed in all +POM121C ENSG00000272391 POM121 transmembrane nucleoporin C 7 75416787-75486271 Predicted intracellular proteins Evidence at transcript level HPA043809, HPA049817 Approved Approved Nucleoplasm
Nuclear membrane Expressed in all Expressed in all parathyroid gland: 28.1 Expressed in all +CD24 CD24A ENSG00000272398 CD24 molecule 6 106969831-106975627 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045879, CAB078471 Supported Vesicles Breast cancer:2.44e-5 (unfavourable), Colorectal cancer:3.29e-4 (favourable), Liver cancer:7.58e-4 (unfavourable) Expressed in all Tissue enhanced thyroid gland: 2706.1 esophagus: 1402.0 Cell line enhanced NTERA-2: 984.0;RPTEC TERT1: 3501.8;SK-BR-3: 1014.5 +FAM47E-STBD1 ENSG00000272414 FAM47E-STBD1 readthrough 4 76251721-76311129 Predicted intracellular proteins Evidence at transcript level HPA053331 Approved Uncertain Plasma membrane
Cytosol Not detected Mixed adipose tissue: 33.2 Cell line enhanced Karpas-707: 24.7 +CFAP206 C6orf165, dJ382I10.1, FLJ25974 ENSG00000272514 Cilia and flagella associated protein 206 6 87407983-87464465 Predicted intracellular proteins Evidence at protein level HPA044891, HPA072261 Approved Approved Nucleoplasm
Cell Junctions Not detected Group enriched 30 fallopian tube: 35.9;testis: 106.8 lung,thyroid gland: 2.3 Cell line enhanced MCF7: 1.7;RPTEC TERT1: 2.0;T-47d: 4.2 +MUSTN1 Mustang ENSG00000272573 Musculoskeletal, embryonic nuclear protein 1 3 52833114-52835219 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 6 skeletal muscle: 414.1 cervix, uterine: 71.5 Cell line enhanced Hep G2: 4.1;RH-30: 5.0 +ZNF595 FLJ31740 ENSG00000272602 Zinc finger protein 595 4 53285-88211 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all placenta: 87.9 Cell line enhanced K-562: 222.3;SH-SY5Y: 169.9 +COG8 DOR1, FLJ22315 ENSG00000272617 Component of oligomeric golgi complex 8 16 69326913-69339667 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041406, HPA049429 Approved Supported Golgi apparatus Not detected Expressed in all testis: 40.0 Expressed in all +DOC2B DOC2BL ENSG00000272636 Double C2 domain beta 17 142789-181636 Predicted intracellular proteins Evidence at protein level HPA043168 Uncertain Breast cancer:3.45e-4 (favourable), Head and neck cancer:8.68e-4 (favourable) Expressed in all Mixed cerebral cortex: 14.4 Group enriched 8 HAP1: 9.4;SH-SY5Y: 39.6 +PCDHB16 KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a ENSG00000272674 Protocadherin beta 16 5 141181399-141186399 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014668 Approved Vesicles
Plasma membrane Mixed Tissue enhanced parathyroid gland: 10.8 ovary: 7.3 Cell line enhanced AN3-CA: 15.6;U-138 MG: 35.8 +CTD-2410N18.5 ENSG00000272772 5 134167170-134226071 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced cerebral cortex: 1.3 endometrium,heart muscle,small intestine: 0.6 Mixed +KRTAP10-7 KAP10.7, KAP18.7, KRTAP18-7 ENSG00000272804 Keratin associated protein 10-7 21 44600597-44602174 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +RP11-302B13.5 ENSG00000272822 12 48903503-48957365 Predicted intracellular proteins Evidence at transcript level HPA068942 Approved Nucleus
Nuclear bodies Not detected Mixed cerebral cortex: 2.1 Cell line enhanced BJ hTERT+: 3.6 +DCP1A HSA275986, SMAD4IP1, SMIF ENSG00000272886 Decapping mRNA 1A 3 53283428-53347610 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA013202 Approved Supported Cytoplasmic bodies Liver cancer:3.25e-5 (unfavourable), Colorectal cancer:9.01e-4 (favourable) Expressed in all Expressed in all endometrium: 19.1 Expressed in all +RP11-309L24.4 ENSG00000272899 7 128866308-128872044 Predicted intracellular proteins Evidence at transcript level Endometrial cancer:8.21e-4 (unfavourable) Mixed Mixed small intestine: 3.7 Cell line enhanced CAPAN-2: 6.0;HMC-1: 4.8 +RBAK-RBAKDN ENSG00000272968 RBAK-RBAKDN readthrough 7 4983718-5073221 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 155 testis: 109.8 cerebral cortex: 0.7 Mixed +C2orf15 MGC29762 ENSG00000273045 Chromosome 2 open reading frame 15 2 99141485-99151487 Predicted intracellular proteins Evidence at transcript level Renal cancer:1.23e-4 (favourable), Ovarian cancer:4.95e-4 (favourable) Mixed Mixed thyroid gland: 9.9 Cell line enhanced SCLC-21H: 13.7 +RP4-583P15.14 ENSG00000273047 20 63738270-63740398 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced kidney: 1.1;liver: 2.4;urinary bladder: 1.3 adipose tissue: 1.0 Cell line enhanced Hep G2: 4.0;HHSteC: 1.0;U-698: 1.5 +RP11-834C11.12 ENSG00000273049 12 53985845-54034888 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced fallopian tube: 1.5 skeletal muscle: 0.8 Cell line enhanced AN3-CA: 8.1;HDLM-2: 3.0 +GRIN2B GluN2B, NMDAR2B ENSG00000273079 Glutamate ionotropic receptor NMDA type subunit 2B 12 13437942-13981957 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA069762 Approved Not detected Tissue enriched 23 cerebral cortex: 13.1 adipose tissue,testis: 0.5 Cell line enhanced AF22: 1.2;CACO-2: 1.2;NTERA-2: 1.8;RPTEC TERT1: 1.3 +LYPD4 MGC42718 ENSG00000273111 LY6/PLAUR domain containing 4 19 41837074-41844697 Predicted secreted proteins Evidence at protein level Not detected Tissue enriched 749 testis: 165.3 bone marrow: 0.2 Not detected +NBPF26 ENSG00000273136 Neuroblastoma breakpoint family member 26 1 120723923-120841481 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Uncertain Approved Vesicles Mixed Expressed in all skin: 51.6 Mixed +RP4-583P15.15 ENSG00000273154 20 63708864-63739103 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Mixed Tissue enhanced adrenal gland: 1.2;appendix: 1.0 duodenum,prostate: 0.5 Mixed +RP11-38C17.1 ENSG00000273155 2 99154998-99195298 Predicted intracellular proteins Evidence at transcript level Not detected Mixed appendix: 1.7 Mixed +CTB-96E2.2 ENSG00000273171 17 28364288-28368012 Predicted intracellular proteins No evidence Not detected Not detected liver: 0.6 Not detected +SNURF ENSG00000273173 SNRPN upstream reading frame 15 24954986-24977850 Predicted intracellular proteins Evidence at protein level HPA065733 Supported Nuclear speckles Mixed Expressed in all cerebral cortex: 197.0 Cell line enhanced NTERA-2: 224.6 +CTC-432M15.3 ENSG00000273217 5 131425891-131796983 Predicted intracellular proteins Evidence at transcript level HPA037982, HPA037983 Uncertain Approved Centrosome
Cytosol Not detected Not detected all non-specific tissues: 0.0 Cell line enhanced A549: 2.2 +C2orf61 ENSG00000273269 Chromosome 2 open reading frame 61 2 47065941-47176511 Predicted intracellular proteins Evidence at transcript level HPA047366, HPA052691 Approved Approved Nucleoplasm
Cytosol Not detected Tissue enriched 224 testis: 22.3 all non-specific tissues: 0.0 Not detected +ZBTB8B DKFZp547H154, RP1-27O5.1, ZNF916B ENSG00000273274 Zinc finger and BTB domain containing 8B 1 32465069-32496686 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055553 Approved Tissue enhanced Not detected cerebral cortex: 0.6 Cell line enhanced SCLC-21H: 1.1 +RP11-136C24.3 ENSG00000273291 3 42809446-43055871 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 13 testis: 2.1 prostate,rectum: 0.1 Not detected +AC011841.1 ENSG00000273496 Unmapped 99351-104855 Predicted intracellular proteins Evidence at transcript level Not detected skin: 0.4 Cell line enhanced A-431: 2.4 +TBC1D3K ENSG00000273513 TBC1 domain family member 3K 17 37924415-37935365 Predicted membrane proteins Evidence at protein level HPA046969, HPA047745, HPA052553 Approved Uncertain Vesicles Not detected Tissue enhanced testis: 1.6 lymph node: 0.3 Cell line enhanced T-47d: 1.3 +FOXD4L6 ENSG00000273514 Forkhead box D4-like 6 9 41126430-41128463 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA012836 Uncertain Approved Nucleus Not detected Not detected cerebral cortex: 0.3 Not detected +AGBL1 CCP4, FLJ32310 ENSG00000273540 ATP/GTP binding protein like 1 15 86079973-87029052 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Not detected Tissue enhanced lung: 1.3;skeletal muscle: 4.4 esophagus: 1.0 Not detected +HIST1H4K dJ160A22.1, H4/d, H4F2iii, H4FD ENSG00000273542 Histone cluster 1 H4 family member k 6 27831216-27831527 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Mixed Not detected appendix: 0.8 Not detected +OR4F16 ENSG00000273547 Olfactory receptor family 4 subfamily F member 16 1 685716-686654 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047705 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +AC136616.1 ENSG00000273554 Unmapped 1139577-1147868 Predicted membrane proteins Evidence at transcript level Group enriched 6 skin: 1.6;testis: 6.9 adrenal gland: 0.6 Cell line enriched 6 AN3-CA: 14.2 +CWC25 CCDC49, FLJ20291 ENSG00000273559 CWC25 spliceosome associated protein homolog 17 38800434-38825481 Predicted intracellular proteins Evidence at protein level CAB014874, HPA062997 Enhanced Enhanced Nuclear speckles Expressed in all Mixed bone marrow: 18.8 Expressed in all +SMIM11B ENSG00000273590 Small integral membrane protein 11B 21 7744962-7777853 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA051321 Uncertain Approved Focal adhesion sites Not detected Expressed in all epididymis: 24.8 Mixed +EPOP C17orf96, LOC100170841, PRR28 ENSG00000273604 Elongin BC and polycomb repressive complex 2 associated protein 17 38671703-38675421 Predicted intracellular proteins Evidence at protein level HPA055190, HPA056555 Enhanced Supported Nucleoplasm
Cytosol
Cytoplasmic bodies Expressed in all Tissue enhanced cerebral cortex: 5.5;testis: 5.0 parathyroid gland: 2.1 Cell line enhanced AN3-CA: 19.3 +ZNHIT3 TRIP3 ENSG00000273611 Zinc finger HIT-type containing 3 17 36486629-36499310 Predicted intracellular proteins Evidence at protein level HPA060019 Approved Mitochondria Expressed in all Expressed in all testis: 43.2 Expressed in all +CT45A7 ENSG00000273696 Cancer/testis antigen family 45 member A7 X 135829247-135837268 Predicted intracellular proteins Evidence at protein level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Not detected Tissue enriched 6 testis: 1.5 cerebral cortex,lung: 0.2 Not detected +HIST1H2BM dJ160A22.3, H2B/e, H2BFE ENSG00000273703 Histone cluster 1 H2B family member m 6 27815044-27815424 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed Tissue enhanced bone marrow: 3.3;lymph node: 2.6 tonsil: 1.5 Cell line enhanced Karpas-707: 14.4;NB-4: 8.4;REH: 7.8;U-266/70: 11.7 +LHX1 LIM-1, LIM1 ENSG00000273706 LIM homeobox 1 17 36936785-36944612 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA073521 Enhanced Endometrial cancer:3.63e-5 (unfavourable) Tissue enhanced Tissue enriched 6 kidney: 1.3 fallopian tube: 0.2 Cell line enhanced HAP1: 3.9;WM-115: 6.9 +AL592183.1 ENSG00000273748 Unmapped 54224-83311 Predicted intracellular proteins Evidence at transcript level HPA049380 Approved Expressed in all gallbladder: 147.3 Mixed +CYFIP1 KIAA0068, P140SRA-1, SHYC ENSG00000273749 Cytoplasmic FMR1 interacting protein 1 15 22867052-22981063 Predicted intracellular proteins Evidence at protein level HPA068106 Approved Renal cancer:4.47e-5 (favourable), Lung cancer:7.39e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 111.9 Mixed +CEACAM20 UNQ9366 ENSG00000273777 Carcinoembryonic antigen related cell adhesion molecule 20 19 44501677-44529788 Predicted membrane proteins Evidence at transcript level Group enriched Group enriched 23 duodenum: 38.8;prostate: 14.3;small intestine: 42.7 gallbladder: 1.3 Cell line enriched 7 U-266/70: 1.0 +HIST1H2BG H2B.1A, H2B/a, H2BFA ENSG00000273802 Histone cluster 1 H2B family member g 6 26215159-26216692 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Renal cancer:1.70e-8 (unfavourable) Expressed in all Tissue enhanced breast: 17.5;prostate: 11.3 bone marrow: 4.6 Cell line enhanced SiHa: 11.2;T-47d: 19.9;U-266/70: 15.0 +USP27X USP27 ENSG00000273820 Ubiquitin specific peptidase 27, X-linked X 49879948-49882565 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA077264 Approved Nucleoplasm
Vesicles Liver cancer:6.14e-4 (unfavourable), Pancreatic cancer:9.31e-4 (favourable) Expressed in all Tissue enhanced placenta: 19.7 cerebral cortex: 10.3 Mixed +TAF9 AD-004, CGI-137, MGC1603, MGC3647, MGC5067, TAF2G, TAFII31, TAFII32, TAFIID32 ENSG00000273841 TATA-box binding protein associated factor 9 5 69364743-69370013 Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:1.48e-5 (unfavourable), Renal cancer:9.20e-4 (unfavourable) Expressed in all Expressed in all testis: 146.1 Expressed in all +NOL12 MGC3731, Nop25, RRP17 ENSG00000273899 Nucleolar protein 12 22 37681673-37693478 Predicted intracellular proteins Evidence at protein level HPA003547 Uncertain Approved Nucleus
Nucleoli
Vesicles Renal cancer:2.56e-6 (unfavourable), Cervical cancer:6.80e-5 (favourable), Urothelial cancer:3.24e-4 (favourable), Lung cancer:9.41e-4 (favourable) Expressed in all Expressed in all adrenal gland: 25.1 Expressed in all +GOLGA6L1 ENSG00000273976 Golgin A6 family-like 1 15 23128268-23136822 Predicted intracellular proteins Evidence at transcript level HPA047733 Uncertain Not detected Tissue enriched 11 testis: 4.5 bone marrow: 0.4 Not detected +HIST1H3G H3/h, H3FH ENSG00000273983 Histone cluster 1 H3 family member g 6 26269405-26271815 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Cervical cancer:8.75e-4 (favourable) Mixed Not detected epididymis,small intestine: 0.5 Cell line enhanced SiHa: 7.2;U-266/70: 4.8 +RP11-475E11.9 ENSG00000274068 1 108837660-108963484 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced parathyroid gland: 1.5 adrenal gland,cerebral cortex: 0.9 Cell line enhanced HDLM-2: 1.8 +GATSL2 GATSL1 ENSG00000274070 GATS protein like 2 7 74964818-75024798 Predicted intracellular proteins Evidence at protein level HPA057229 Uncertain Expressed in all Tissue enhanced cerebral cortex: 14.9 skeletal muscle: 13.8 Cell line enhanced A549: 24.5 +OR4M2 ENSG00000274102 Olfactory receptor family 4 subfamily M member 2 15 22080527-22081659 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA058889 Uncertain Not detected Tissue enriched 10 testis: 1.2 cerebral cortex: 0.1 Not detected +AC133551.1 ENSG00000274175 Unmapped 17234-19833 Predicted intracellular proteins Evidence at transcript level Group enriched 28 epididymis: 7.4;testis: 4.1 placenta: 0.2 Not detected +NATD1 C17orf103, Gtlf3b, MGC33894 ENSG00000274180 N-acetyltransferase domain containing 1 17 21238870-21253410 Predicted intracellular proteins Evidence at protein level Renal cancer:3.55e-6 (favourable) Expressed in all Expressed in all thyroid gland: 17.0 Cell line enhanced BEWO: 22.1 +H2AFB1 ENSG00000274183 H2A histone family member B1 X 154884972-154885558 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 9 testis: 4.3 bone marrow,skin: 0.4 Cell line enriched 26 HDLM-2: 12.2 +ANTXRL ENSG00000274209 Anthrax toxin receptor-like 10 46286345-46330207 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Tissue enriched Tissue enriched 23 testis: 15.5 bone marrow: 0.6 Not detected +SOCS7 NAP4, NCKAP4 ENSG00000274211 Suppressor of cytokine signaling 7 17 38352228-38405593 Predicted intracellular proteins Evidence at protein level HPA004475 Approved Approved Cytosol Breast cancer:7.49e-4 (unfavourable), Endometrial cancer:7.87e-4 (unfavourable) Expressed in all Tissue enhanced testis: 54.4 thyroid gland: 13.1 Expressed in all +TBC1D3H ENSG00000274226 TBC1 domain family member 3H 17 36377531-36388423 Predicted membrane proteins Evidence at protein level HPA046969, HPA047745, HPA052553 Approved Approved Vesicles Not detected Tissue enhanced testis: 2.7;urinary bladder: 1.1 cervix, uterine: 0.6 Cell line enriched 10 CAPAN-2: 5.1 +GGTLC3 ENSG00000274252 Gamma-glutamyltransferase light chain 3 22 18516344-18518161 Predicted intracellular proteins Evidence at protein level HPA045635, HPA047534 Uncertain Not detected Tissue enhanced lung: 1.9;testis: 1.0 small intestine: 0.5 Cell line enhanced U-2197: 1.0 +HIST1H3B H3/l, H3FL ENSG00000274267 Histone cluster 1 H3 family member b 6 26031650-26032060 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA042570 Supported Mixed Tissue enriched 6 bone marrow: 6.1 lymph node: 0.9 Mixed +GAGE13 GAGE12A ENSG00000274274 G antigen 13 X 49331616-49338952 Predicted intracellular proteins Evidence at protein level HPA043232 Supported Uncertain Golgi apparatus
Plasma membrane
Cytosol Not detected Tissue enriched 553 testis: 59.6 stomach: 0.1 Cell line enriched 6 AN3-CA: 685.8 +CBSL ENSG00000274276 Cystathionine-beta-synthase like 21 6444869-6468040 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001223 Supported Approved Nucleoli
Vesicles Mixed Tissue enhanced cerebral cortex: 45.9;liver: 27.3 thyroid gland: 22.2 Cell line enhanced AN3-CA: 123.4;NTERA-2: 245.4;SH-SY5Y: 82.5 +ADRA2B ADRA2L1, ADRA2RL1, ADRARL1 ENSG00000274286 Adrenoceptor alpha 2B 2 96112875-96116245 Predicted membrane proteins Evidence at transcript level HPA066029 Approved Mixed Mixed epididymis: 5.1 Cell line enhanced BEWO: 1.5 +HIST1H2BE H2B.h, H2B/h, H2BFH ENSG00000274290 Histone cluster 1 H2B family member e 6 26172059-26184655 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed Mixed prostate: 2.9 Mixed +ZNF658 DKFZp572C163, FLJ32813, MGC35232 ENSG00000274349 Zinc finger protein 658 9 66856426-66932141 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047730, HPA048668 Uncertain Approved Nucleoplasm Mixed Mixed skin: 9.7 Mixed +TMEM269 ENSG00000274386 Transmembrane protein 269 1 42785007-42816619 Predicted membrane proteins Evidence at transcript level Not detected Not detected testis: 0.9 Mixed +TPTE CT44, PTEN2 ENSG00000274391 Transmembrane phosphatase with tensin homology 21 10521553-10606140 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA049690, HPA068342 Enhanced Approved Endoplasmic reticulum
Cytosol Tissue enriched Tissue enriched 247 testis: 191.3 placenta: 0.7 Cell line enhanced BEWO: 6.4;K-562: 7.3;Karpas-707: 4.6;PC-3: 4.4;RPMI-8226: 6.2;U-2 OS: 4.3;U-266/70: 5.8 +TBC1D3D ENSG00000274419 TBC1 domain family member 3D 17 38003976-38014902 Predicted membrane proteins Evidence at protein level HPA046969, HPA047745, HPA052553 Approved Uncertain Vesicles Not detected Tissue enhanced small intestine: 5.5;testis: 3.4 skin: 3.2 Cell line enhanced CAPAN-2: 8.4;HaCaT: 6.1;HeLa: 5.2;RT4: 3.7 +C8orf89 ENSG00000274443 Chromosome 8 open reading frame 89 8 73241329-73259502 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 8 testis: 13.3 cervix, uterine: 1.5 Not detected +TBC1D3L ENSG00000274512 TBC1 domain family member 3L 17 37977972-37989048 Predicted membrane proteins Evidence at protein level HPA046969, HPA047745, HPA052553 Approved Uncertain Vesicles Mixed Mixed skin: 42.2 Cell line enhanced BEWO: 37.5 +RCC1L WBSCR16 ENSG00000274523 RCC1 like 7 75027122-75074228 Predicted intracellular proteins Evidence at protein level HPA052184, HPA060643 Approved Approved Nucleus
Cytosol Glioma:6.65e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 36.4 Expressed in all +SEBOX OG9, OG9X ENSG00000274529 SEBOX homeobox 17 28364268-28365244 Predicted intracellular proteins No evidence HPA045689 Uncertain Not detected Not detected testis: 0.4 Not detected +CH507-42P11.1 ENSG00000274559 21 5972924-5973383 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Uncertain Supported Nucleoplasm
Cytosol Not detected Mixed prostate: 8.2 Cell line enhanced K-562: 40.6;U-2 OS: 43.9;U-266/84: 32.4 +DGKK ENSG00000274588 Diacylglycerol kinase kappa X 50365409-50470738 Enzymes, Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 7 adrenal gland: 4.5 cerebral cortex: 0.6 Cell line enriched 14 Hep G2: 23.8 +RIMBP3B ENSG00000274600 RIMS binding protein 3B 22 21383374-21389478 Predicted intracellular proteins Evidence at protein level HPA001183 Supported Uncertain Vesicles
Plasma membrane Not detected Tissue enriched 26 testis: 12.1 parathyroid gland: 0.4 Cell line enhanced RH-30: 1.0;THP-1: 1.0 +TBC1D3 DKFZp434P2235, PRC17, TBC1D3A ENSG00000274611 TBC1 domain family member 3 17 38181659-38192541 Predicted membrane proteins Evidence at protein level HPA046969, HPA047745, HPA052553 Approved Uncertain Vesicles Not detected Tissue enhanced small intestine: 4.0;testis: 6.8 endometrium: 3.6 Cell line enhanced AF22: 7.5;REH: 4.5;U-138 MG: 6.4;U-266/70: 7.8;U-266/84: 3.0;U-698: 3.6 +HIST1H4F H4, H4/c, H4FC ENSG00000274618 Histone cluster 1 H4 family member f 6 26240426-26240737 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Tissue enhanced Not detected bone marrow: 0.7 Cell line enhanced MCF7: 1.2;MOLT-4: 5.2;REH: 2.6 +HIST1H2BO H2B.2, H2B/n, H2BFN ENSG00000274641 Histone cluster 1 H2B family member o 6 27893463-27893843 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Urothelial cancer:4.89e-4 (favourable) Mixed Tissue enhanced bone marrow: 2.1 lymph node,placenta: 1.3 Cell line enhanced U-266/84: 32.7 +CCL23 Ckb-8, CKb8, MIP-3, MPIF-1, SCYA23 ENSG00000274736 C-C motif chemokine ligand 23 17 36013056-36017968 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA042015 Uncertain Mixed Tissue enhanced smooth muscle: 15.4 lung: 11.1 Group enriched 5 HEL: 15.9;THP-1: 25.4;U-937: 5.1 +ELOA3D TCEB3CL2 ENSG00000274744 Elongin A3 family member D 18 46962768-46964408 Predicted intracellular proteins No evidence HPA048971, HPA049178, HPA050086 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +KRTAP7-1 KAP7.1 ENSG00000274749 Keratin associated protein 7-1 (gene/pseudogene) 21 30829039-30829759 Predicted intracellular proteins Evidence at transcript level Tissue enriched Not detected skin: 0.1 Not detected +HIST1H3E H3.1, H3/d, H3FD ENSG00000274750 Histone cluster 1 H3 family member e 6 26224199-26227473 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Expressed in all Mixed epididymis: 6.0 Cell line enhanced EFO-21: 10.0;SCLC-21H: 14.1 +PRAMEF27 ENSG00000274764 PRAME family member 27 1 13049476-13056491 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +F8A2 ENSG00000274791 Coagulation factor VIII-associated 2 X 155382115-155383230 Predicted intracellular proteins Evidence at protein level HPA046960 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +AC171558.1 ENSG00000274792 Unmapped 386278-387620 Predicted membrane proteins Evidence at transcript level HPA057442 Uncertain Uncertain Centrosome Tissue enriched 11 testis: 4.3 cerebral cortex: 0.4 Cell line enriched 29 U-2 OS: 3.3 +TBC1D3B PRC17, TBC1D3I ENSG00000274808 TBC1 domain family member 3B 17 36165681-36176636 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046969, HPA047745, HPA052553 Approved Uncertain Vesicles Not detected Tissue enhanced skin: 6.3;testis: 6.0 spleen: 2.9 Cell line enhanced CAPAN-2: 7.5;T-47d: 5.6 +NPHP3-ACAD11 ENSG00000274810 NPHP3-ACAD11 readthrough (NMD candidate) 3 132558142-132722459 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced ovary: 4.8 endometrium: 3.2 Cell line enhanced ASC TERT1: 4.4 +AC145212.1 ENSG00000274847 Unmapped 53594-115055 Predicted intracellular proteins Evidence at transcript level HPA053929 Uncertain Uncertain Intermediate filaments Mixed adrenal gland: 10.2 Mixed +RP11-214K3.25 ENSG00000274874 12 123973944-124088594 Predicted intracellular proteins Evidence at transcript level Not detected Mixed cerebral cortex: 1.3 Mixed +PANO1 PANO ENSG00000274897 Proapoptotic nucleolar protein 1 11 797511-799190 Predicted intracellular proteins Evidence at transcript level Mixed Mixed cerebral cortex,skin: 1.4 Cell line enhanced BEWO: 5.3;SCLC-21H: 5.1 +TBC1D3I ENSG00000274933 TBC1 domain family member 3I 17 36253456-36264553 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046969, HPA047745, HPA052553 Approved Uncertain Vesicles Not detected Tissue enhanced testis: 1.1 skin: 0.3 Cell line enriched 6 CAPAN-2: 4.7 +RP5-864K19.6 ENSG00000274944 1 38864501-38881617 Predicted intracellular proteins Evidence at transcript level HPA041188 Uncertain Not detected Tissue enhanced testis: 11.6 lymph node: 3.6 Mixed +HIST1H2AH dJ86C11.1, H2A/S, H2AFALii ENSG00000274997 Histone cluster 1 H2A family member h 6 27147129-27147515 Predicted intracellular proteins Evidence at protein level CAB004030, HPA041189 Supported Mixed Tissue enhanced bone marrow: 7.4 testis: 2.5 Mixed +ZNF280B 5'OY11.1, SUHW2, ZNF279, ZNF632 ENSG00000275004 Zinc finger protein 280B 22 22484421-22509154 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059519 Uncertain Approved Nucleoplasm Mixed Tissue enriched 7 testis: 12.6 cerebral cortex: 1.8 Cell line enhanced K-562: 8.3;U-2 OS: 4.7 +MLLT6 AF17, FLJ23480 ENSG00000275023 MLLT6, PHD finger domain containing 17 38705542-38729803 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA004021 Approved Approved Nucleus Head and neck cancer:3.98e-4 (favourable), Breast cancer:4.18e-4 (favourable), Pancreatic cancer:7.41e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 36.4 Expressed in all +TP53TG3E ENSG00000275034 TP53 target 3 family member E 16 33303739-33306935 Predicted intracellular proteins Evidence at transcript level Not detected Not detected placenta: 0.2 Not detected +RP11-546B8.6 ENSG00000275038 5 171305981-171308755 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Cell line enhanced SH-SY5Y: 1.9 +PPP4R3B FLFL2, FLJ31474, KIAA1387, PSY2, SMEK2 ENSG00000275052 Protein phosphatase 4 regulatory subunit 3B 2 55547292-55618880 Predicted intracellular proteins Evidence at protein level HPA001233, CAB017185 Approved Supported Nucleoplasm
Nuclear speckles
Centrosome Renal cancer:6.03e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 58.0 Expressed in all +AC233755.1 ENSG00000275063 Unmapped 41444-41876 Predicted secreted proteins Evidence at transcript level Tissue enhanced urinary bladder: 1019.5 tonsil: 662.1 Cell line enriched 8 REH: 129.3 +SYNRG AP1GBP1, MGC104959, SYNG ENSG00000275066 Synergin gamma 17 37514797-37609496 Predicted intracellular proteins Evidence at protein level HPA023554, HPA023555 Approved Approved Cytosol Urothelial cancer:3.96e-4 (favourable) Expressed in all Expressed in all testis: 20.4 Expressed in all +NUDT18 FLJ22494, MTH3 ENSG00000275074 Nudix hydrolase 18 8 22106872-22109419 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028581, HPA030125 Approved Supported Nucleoplasm
Golgi apparatus Endometrial cancer:2.49e-6 (favourable), Cervical cancer:1.43e-4 (favourable), Pancreatic cancer:2.47e-4 (favourable), Renal cancer:8.30e-4 (favourable) Expressed in all Mixed epididymis: 16.2 Mixed +ZNF2 A1-5, Zfp661, ZNF661 ENSG00000275111 Zinc finger protein 2 2 95165432-95184317 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041358 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Lung cancer:4.69e-5 (favourable) Expressed in all Mixed parathyroid gland: 6.4 Expressed in all +GAGE2E GAGE8 ENSG00000275113 G antigen 2E X 49341192-49345922 Predicted intracellular proteins Evidence at transcript level HPA043232 Approved Uncertain Golgi apparatus
Plasma membrane
Cytosol Not detected Group enriched 60 stomach: 15.4;testis: 8.6 small intestine: 0.2 Group enriched 5 AN3-CA: 943.7;K-562: 455.5;T-47d: 231.8 +HIST1H4L H4.k, H4/k, H4FK ENSG00000275126 Histone cluster 1 H4 family member l 6 27873199-27873510 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Tissue enhanced Not detected bone marrow: 0.3 Cell line enhanced MOLT-4: 4.5;NB-4: 1.8;REH: 1.3 +CCL16 CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4 ENSG00000275152 C-C motif chemokine ligand 16 17 35976493-35981496 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Tissue enriched Tissue enriched 91 liver: 60.8 spleen: 0.6 Cell line enriched 19 Hep G2: 6.8 +RP11-385J1.3 ENSG00000275163 3 178419123-178843300 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 6 fallopian tube: 8.8 kidney: 1.5 Cell line enriched 10 HSkMC: 1.0 +LENG9 ENSG00000275183 Leukocyte receptor cluster member 9 19 54461796-54463711 Predicted intracellular proteins Evidence at protein level HPA051671, HPA053556 Enhanced Approved Nucleoli fibrillar center Endometrial cancer:9.99e-5 (favourable) Expressed in all Mixed duodenum: 5.2 Cell line enhanced HaCaT: 5.6 +HIST1H2AK H2A/d, H2AFD ENSG00000275221 Histone cluster 1 H2A family member k 6 27837947-27838339 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Not detected Mixed testis: 2.3 Cell line enhanced A549: 2.0;AN3-CA: 2.2;SCLC-21H: 2.8;U-266/84: 2.7 +AC171558.2 ENSG00000275249 Unmapped 372322-373405 Predicted membrane proteins Evidence at transcript level HPA058889 Uncertain Tissue enriched 26 testis: 2.5 all non-specific tissues: 0.0 Not detected +CCL4 Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4 ENSG00000275302 C-C motif chemokine ligand 4 17 36103590-36105621 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB007805 Approved Endometrial cancer:1.97e-5 (favourable), Renal cancer:1.68e-4 (unfavourable), Colorectal cancer:3.54e-4 (favourable), Melanoma:3.97e-4 (favourable) Expressed in all Tissue enhanced spleen: 24.8 lymph node: 17.6 Group enriched 22 Karpas-707: 2.2;U-266/70: 5.1;U-266/84: 2.4 +PRAG1 DKFZp761P0423, NACK, PEAK2, PRAGMIN, SgK223 ENSG00000275342 PEAK1 related kinase activating pseudokinase 1 8 8317736-8386498 Enzymes, Predicted intracellular proteins Evidence at protein level HPA012066 Uncertain Approved Nucleoplasm
Centrosome
Cytosol Renal cancer:4.81e-4 (favourable) Expressed in all Tissue enhanced thyroid gland: 28.3 small intestine: 12.2 Cell line enhanced A549: 45.2 +C7orf77 ENSG00000275356 Chromosome 7 open reading frame 77 7 124777292-124790689 Predicted intracellular proteins Evidence at transcript level Not detected Not detected lung: 0.5 Cell line enriched 8 HDLM-2: 3.8 +HIST1H3I H3.f, H3/f, H3FF ENSG00000275379 Histone cluster 1 H3 family member i 6 27871905-27872315 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Tissue enhanced Tissue enhanced bone marrow: 1.1 appendix: 0.6 Cell line enhanced HEL: 2.6;MOLT-4: 4.4;NB-4: 2.3;REH: 5.1 +CCL18 AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18 ENSG00000275385 C-C motif chemokine ligand 18 17 36064280-36072032 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level Expressed in all Tissue enhanced adipose tissue: 20.9;lung: 13.0;tonsil: 10.5 lymph node: 6.2 Not detected +FCGBP FC(GAMMA)BP ENSG00000275395 Fc fragment of IgG binding protein 19 39863323-39934626 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003517, HPA003564 Enhanced Approved Golgi apparatus
Plasma membrane
Cytokinetic bridge Ovarian cancer:9.70e-6 (unfavourable), Head and neck cancer:1.28e-5 (favourable), Liver cancer:4.74e-5 (unfavourable), Thyroid cancer:4.27e-4 (unfavourable) Expressed in all Tissue enhanced colon: 166.7 cervix, uterine: 83.5 Cell line enhanced A549: 2.7;RH-30: 6.8 +HNF1B HNF1beta, LFB3, MODY5, TCF2, VHNF1 ENSG00000275410 HNF1 homeobox B 17 37686432-37745247 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002083, CAB068192 Enhanced Supported Nucleoplasm Urothelial cancer:2.51e-6 (favourable), Renal cancer:6.00e-4 (favourable) Tissue enhanced Tissue enhanced gallbladder: 21.5;kidney: 25.3 lung: 9.6 Cell line enhanced A549: 16.8;CACO-2: 17.9;EFO-21: 26.2;RPTEC TERT1: 95.5 +CH507-9B2.5 ENSG00000275464 21 5130871-5154734 Predicted intracellular proteins Evidence at protein level HPA024573 Uncertain Approved Nucleoli
Cytosol Mixed Expressed in all cerebral cortex: 16.0 Mixed +C17orf98 LOC388381 ENSG00000275489 Chromosome 17 open reading frame 98 17 38835088-38841455 Predicted intracellular proteins Evidence at transcript level HPA051696 Uncertain Approved Nucleoli
Intermediate filaments Not detected Tissue enriched 50 testis: 9.5 adipose tissue,skin: 0.1 Cell line enriched 7 hTCEpi: 1.9 +FAM236A DMRTC1-AS1, LINC00684 ENSG00000275520 Family with sequence similarity 235 member A X 72938163-72938958 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 46 testis: 79.7 lymph node: 1.7 Not detected +ELOA3C ENSG00000275553 Elongin A3 family member C 18 46968695-46969912 Predicted intracellular proteins No evidence HPA049178, HPA050086 Uncertain Not detected Not detected epididymis: 0.1 Not detected +GRIFIN ENSG00000275572 Galectin-related inter-fiber protein 7 2474844-2476894 Predicted intracellular proteins Evidence at transcript level Not detected Not detected skin: 0.7 Not detected +XKR5 ENSG00000275591 XK related 5 8 6808517-6835644 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced cervix, uterine: 1.0 testis: 0.6 Cell line enhanced AF22: 3.0;NTERA-2: 1.9;SCLC-21H: 1.8;SH-SY5Y: 3.6 +HIST1H4G H4/l, H4FL ENSG00000275663 Histone cluster 1 H4 family member g 6 26246681-26246977 Predicted intracellular proteins Evidence at protein level HPA042201 Supported Not detected Not detected small intestine: 0.2 Not detected +RP11-697E2.12 ENSG00000275674 15 90266317-90314499 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced duodenum: 1.2 cerebral cortex,small intestine: 0.8 Cell line enhanced BEWO: 1.8 +RP11-249C24.12 ENSG00000275691 16 56676132-56677763 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced thyroid gland: 1.1 rectum: 0.7 Not detected +AATF BFR2, CHE-1, CHE1, DED ENSG00000275700 Apoptosis antagonizing transcription factor 17 36948875-37056871 Predicted intracellular proteins Evidence at protein level HPA004940 Uncertain Renal cancer:4.14e-5 (unfavourable), Liver cancer:6.62e-5 (unfavourable) Expressed in all Expressed in all lymph node: 19.9 Expressed in all +HIST1H2BH H2B/j, H2BFJ ENSG00000275713 Histone cluster 1 H2B family member h 6 26251651-26253710 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Head and neck cancer:7.52e-4 (unfavourable) Mixed Tissue enhanced duodenum: 3.0 small intestine: 1.2 Cell line enhanced U-266/70: 12.9 +HIST1H3A H3/A, H3FA ENSG00000275714 Histone cluster 1 H3 family member a 6 26020490-26020900 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Mixed Group enriched 5 bone marrow: 6.7;epididymis: 1.8;testis: 3.7 lung: 0.7 Cell line enhanced U-2 OS: 5.3 +CCL15 HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3 ENSG00000275718 C-C motif chemokine ligand 15 17 35996440-36002038 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA058608 Approved Golgi apparatus
Vesicles Urothelial cancer:3.02e-4 (favourable) Tissue enhanced Tissue enhanced duodenum: 21.5;rectum: 30.6;small intestine: 26.6 colon: 18.9 Cell line enriched 12 Hep G2: 22.7 +LYZL6 LYC1, PRO1485, TKAL754 ENSG00000275722 Lysozyme like 6 17 35934518-35943699 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA025734, HPA053073 Supported Not detected Not detected testis: 0.1 Not detected +RP11-449H3.3 ENSG00000275740 5 146203550-146339251 Predicted intracellular proteins Evidence at transcript level HPA035944, HPA036422 Approved Approved Nuclear speckles Not detected Tissue enriched 5 testis: 12.2 thyroid gland: 2.4 Mixed +HNRNPCL2 HNRNPCP5 ENSG00000275774 Heterogeneous nuclear ribonucleoprotein C-like 2 1 13115496-13116854 Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +RIMBP3 KIAA1666, RIMBP3.1, RIMBP3A ENSG00000275793 RIMS binding protein 3 22 18605815-18611919 Predicted intracellular proteins Evidence at protein level HPA001183 Supported Uncertain Vesicles
Plasma membrane Not detected Tissue enriched 37 testis: 45.4 parathyroid gland: 1.2 Mixed +ARHGAP23 KIAA1501 ENSG00000275832 Rho GTPase activating protein 23 17 38419280-38512392 Predicted intracellular proteins Evidence at protein level HPA019818, HPA047291 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:5.38e-5 (unfavourable), Endometrial cancer:6.87e-5 (unfavourable), Pancreatic cancer:3.24e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 41.9 Cell line enhanced HaCaT: 260.4 +TUBGCP5 GCP5, KIAA1899 ENSG00000275835 Tubulin gamma complex associated protein 5 15 22983192-23039673 Predicted intracellular proteins Evidence at protein level HPA039366, HPA040366 Supported Supported Centrosome
Cytosol Expressed in all Expressed in all testis: 24.5 Expressed in all +AC136612.1 ENSG00000275869 Unmapped 933862-936467 Predicted intracellular proteins Evidence at transcript level Tissue enriched 5 testis: 4.3 epididymis: 0.8 Not detected +U2AF1L5 ENSG00000275895 U2 small nuclear RNA auxiliary factor 1 like 5 21 6484623-6499261 Predicted intracellular proteins Evidence at protein level HPA044833, HPA052083 Supported Uncertain Nucleoplasm Not detected Expressed in all tonsil: 100.1 Expressed in all +PRSS2 TRY2 ENSG00000275896 Protease, serine 2 7 142760398-142774564 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA062452, HPA063471 Supported Approved Endoplasmic reticulum
Vesicles Breast cancer:2.32e-4 (favourable) Tissue enriched Tissue enriched 53 pancreas: 30215.4 small intestine: 567.7 Group enriched 6 RPMI-8226: 46.1;U-2 OS: 14.3 +TBC1D3F ENSG00000275954 TBC1 domain family member 3F 17 36428618-36439566 Predicted membrane proteins Evidence at protein level HPA046969 Uncertain Vesicles Not detected Tissue enriched 14 testis: 1.9 bone marrow,gallbladder: 0.1 Not detected +SPATA31A3 DKFZp434B204, FAM75A3 ENSG00000275969 SPATA31 subfamily A member 3 9 66986304-66992583 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 52 testis: 5.1 all non-specific tissues: 0.0 Not detected +CH507-42P11.8 ENSG00000275993 21 6111134-6123739 Predicted membrane proteins Evidence at transcript level HPA038211 Uncertain Expressed in all Mixed adrenal gland: 73.0 Cell line enhanced HeLa: 61.0;Karpas-707: 90.2;LHCN-M2: 73.9;SiHa: 93.6 +AC007325.1 ENSG00000276017 Unmapped 72411-74814 Predicted intracellular proteins Evidence at transcript level Tissue enriched 89 testis: 16.5 adipose tissue,gallbladder,smooth muscle,spleen,urinary bladder: 0.1 Not detected +DUSP14 MKP-L, MKP6 ENSG00000276023 Dual specificity phosphatase 14 17 37489831-37513501 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019911 Approved Approved Nucleoplasm
Cytosol Renal cancer:6.97e-9 (unfavourable) Expressed in all Tissue enhanced fallopian tube: 5.1 skin: 2.7 Cell line enhanced BJ hTERT+ SV40 Large T+ RasG12V: 15.2;HBF TERT88: 21.7;WM-115: 13.0 +SPATA31A7 FAM75A4, FAM75A7, SPATA31A4 ENSG00000276040 SPATA31 subfamily A member 7 9 61190003-61196280 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 26 testis: 2.6 all non-specific tissues: 0.0 Not detected +UHRF1 FLJ21925, ICBP90, Np95, RNF106, TDRD22 ENSG00000276043 Ubiquitin like with PHD and ring finger domains 1 19 4903080-4962154 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA049408, HPA055446 Enhanced Supported Nucleoplasm Pancreatic cancer:4.52e-5 (unfavourable), Liver cancer:1.63e-4 (unfavourable), Melanoma:6.81e-4 (unfavourable) Expressed in all Tissue enhanced lymph node: 18.8 bone marrow: 17.5 Expressed in all +ORAI1 CRACM1, FLJ14466, TMEM142A ENSG00000276045 ORAI calcium release-activated calcium modulator 1 12 121626550-121642677 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA016583, HPA061823 Approved Supported Cytosol Ovarian cancer:4.30e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 47.9 Expressed in all +CCL4L2 ENSG00000276070 C-C motif chemokine ligand 4 like 2 17 36210924-36212878 Predicted secreted proteins Evidence at protein level Expressed in all Tissue enhanced bone marrow: 19.4 gallbladder: 10.9 Cell line enhanced Daudi: 2.9;HMC-1: 5.0;U-266/70: 6.7 +CH507-152C13.3 ENSG00000276076 21 6560714-6564489 Predicted intracellular proteins Evidence at transcript level HPA037737, HPA038430 Approved Approved Nucleoplasm
Cytosol Not detected Tissue enriched 13 kidney: 57.2 liver: 4.5 Cell line enriched 178 Hep G2: 25.5 +CCL3L3 CCL3L1, D17S1718, G0S19-2, LD78BETA, MGC12815, SCYA3L, SCYA3L1 ENSG00000276085 C-C motif chemokine ligand 3 like 3 17 36194869-36196758 Predicted secreted proteins Evidence at protein level Expressed in all Group enriched 8 bone marrow: 7.4;gallbladder: 1.5 lymph node,urinary bladder: 0.5 Group enriched 33 U-266/70: 37.7;U-266/84: 73.6 +OR13C2 ENSG00000276119 Olfactory receptor family 13 subfamily C member 2 9 104604671-104605627 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected cerebral cortex,fallopian tube,thyroid gland: 0.1 Not detected +HIST1H4I H4/m, H4FM ENSG00000276180 Histone cluster 1 H4 family member i 6 27138588-27139881 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Renal cancer:1.32e-5 (unfavourable), Cervical cancer:9.70e-4 (favourable) Expressed in all Mixed thyroid gland: 6.1 Cell line enhanced K-562: 67.9;SiHa: 46.7;U-2 OS: 76.3;U-266/84: 55.8 +ANKRD20A3 ENSG00000276203 Ankyrin repeat domain 20 family member A3 9 66106815-66153135 Predicted intracellular proteins Evidence at transcript level HPA043239, HPA047112, HPA047167, HPA047766, HPA051753 Uncertain Not detected Not detected testis: 0.4 Cell line enhanced HDLM-2: 1.2 +PIK3R6 C17orf38, FLJ34500, HsT41028, p87PIKAP ENSG00000276231 Phosphoinositide-3-kinase regulatory subunit 6 17 8802723-8867677 Predicted intracellular proteins Evidence at protein level HPA023077 Approved Renal cancer:1.50e-6 (unfavourable) Mixed Mixed spleen: 4.1 Cell line enriched 7 HMC-1: 131.5 +TADA2A ADA2, ADA2A, hADA2, TADA2L ENSG00000276234 Transcriptional adaptor 2A 17 37406874-37479730 Predicted intracellular proteins Evidence at transcript level HPA076497 Approved Nuclear speckles Renal cancer:2.25e-5 (unfavourable) Expressed in all Mixed testis: 13.8 Mixed +AC011043.1 ENSG00000276256 Homo sapiens uncharacterized LOC389831 (LOC389831), transcript variant 3, mRNA. Unmapped 42939-49164 Predicted intracellular proteins Evidence at transcript level Mixed kidney: 69.3 Mixed +KCNE1B ENSG00000276289 Potassium voltage-gated channel subfamily E regulatory subunit 1B 21 7816675-7829926 Predicted membrane proteins Evidence at transcript level Not detected Tissue enhanced fallopian tube: 9.1;heart muscle: 4.0 kidney: 2.9 Cell line enhanced CACO-2: 1.5 +PIP4K2B PIP5K2B, PIP5KIIB, PIP5KIIbeta ENSG00000276293 Phosphatidylinositol-5-phosphate 4-kinase type 2 beta 17 38765689-38800126 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA047875, HPA062220 Approved Supported Nucleoplasm Thyroid cancer:1.36e-4 (favourable), Liver cancer:4.54e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 51.6 Expressed in all +RP5-874C20.8 ENSG00000276302 6 28267121-28281580 Predicted intracellular proteins Evidence at transcript level Not detected Mixed cerebral cortex: 1.7 Cell line enhanced HEK 293: 1.9 +AC004556.1 ENSG00000276345 Unmapped 2585-11802 Predicted intracellular proteins Evidence at protein level HPA050406 Uncertain Supported Nucleoli fibrillar center
Mitochondria Mixed breast: 24.8 Cell line enhanced NB-4: 110.2;PC-3: 145.9;WM-115: 112.0 +HIST1H2AJ H2A/E, H2AFE ENSG00000276368 Histone cluster 1 H2A family member j 6 27814354-27814740 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Mixed Tissue enhanced bone marrow: 6.4 lymph node: 1.4 Cell line enhanced MCF7: 14.3 +CCL14 CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2 ENSG00000276409 C-C motif chemokine ligand 14 17 35983291-35987004 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB004423, HPA030268 Uncertain Mixed Tissue enhanced spleen: 271.8 adipose tissue: 123.7 Cell line enriched 53 HUVEC TERT2: 46.6 +HIST1H2BB H2B/f, H2BFF ENSG00000276410 Histone cluster 1 H2B family member b 6 26043277-26043657 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed Group enriched 5 bone marrow: 1.1;testis: 3.1 esophagus,lymph node: 0.3 Cell line enhanced MOLT-4: 1.9;THP-1: 1.9;U-266/84: 2.2 +FAM25C bA164N7.4 ENSG00000276430 Family with sequence similarity 25 member C 10 47995355-47999791 Predicted intracellular proteins Evidence at transcript level HPA044808 Uncertain Tissue enhanced Group enriched 14 breast: 5.3;esophagus: 4.0;skin: 9.0;small intestine: 4.3;tonsil: 2.1 skeletal muscle,testis: 0.3 Cell line enriched 5 SK-BR-3: 12.1 +PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 Protocadherin gamma subfamily B, 5 5 141397987-141512979 Predicted membrane proteins Evidence at protein level HPA008755, HPA010580 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cytosol Mixed Tissue enhanced parathyroid gland: 19.8 thyroid gland: 7.6 Cell line enhanced ASC diff: 45.6;ASC TERT1: 34.8;BJ hTERT+ SV40 Large T+: 27.3;BJ hTERT+ SV40 Large T+ RasG12V: 31.8 +SPATA31A5 FAM75A5 ENSG00000276581 SPATA31 subfamily A member 5 9 60914374-60920650 Predicted membrane proteins No evidence Not detected Not detected testis: 0.7 Not detected +RAB7B MGC16212, MGC9726 ENSG00000276600 RAB7B, member RAS oncogene family 1 205976740-206003461 Predicted intracellular proteins Evidence at protein level Endometrial cancer:4.87e-4 (unfavourable) Expressed in all Tissue enhanced skin: 59.9 gallbladder: 22.9 Cell line enhanced HBEC3-KT: 23.4;HMC-1: 75.9;hTCEpi: 26.8 +CH507-9B2.4 ENSG00000276612 21 5116343-5133805 Predicted intracellular proteins Evidence at transcript level Not detected Not detected adrenal gland: 0.9 Cell line enhanced RH-30: 3.3 +DACH1 DACH ENSG00000276644 Dachshund family transcription factor 1 13 71437966-71867192 Predicted intracellular proteins Evidence at protein level HPA012672 Approved Supported Nucleoplasm
Vesicles Mixed Mixed cervix, uterine: 15.0 Cell line enhanced HAP1: 23.2;HL-60: 30.0;SCLC-21H: 43.5;SH-SY5Y: 31.4;THP-1: 18.1 +PADI6 ENSG00000276747 Peptidyl arginine deiminase 6 1 17372196-17401699 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +AC136352.1 ENSG00000276760 Unmapped 136160-167571 Predicted intracellular proteins No evidence HPA042822 Uncertain Not detected all non-specific tissues: 0.0 Not detected +HIST1H2AL dJ193B12.9, H2A/i, H2AFI ENSG00000276903 Histone cluster 1 H2A family member l 6 27865355-27865747 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Mixed Tissue enriched 6 bone marrow: 5.2 parathyroid gland: 0.8 Cell line enhanced MOLT-4: 5.3 +RP4-608O15.3 ENSG00000276911 1 196819745-196959210 Predicted secreted proteins Evidence at protein level HPA038915, HPA040726, HPA049813 Supported Not detected Tissue enriched 527 liver: 203.7 kidney: 0.3 Not detected +GSTTP1 HS322B1A ENSG00000276950 Glutathione S-transferase theta pseudogene 1 22 23998401-24005453 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.4 Not detected +HIST1H4E H4/j, H4FJ ENSG00000276966 Histone cluster 1 H4 family member e 6 26204552-26206038 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Renal cancer:2.00e-6 (unfavourable) Expressed in all Mixed prostate: 2.3 Cell line enhanced U-266/70: 8.6 +HNRNPCL3 ENSG00000277058 Heterogeneous nuclear ribonucleoprotein C-like 3 1 13060869-13062229 Predicted intracellular proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +HIST1H2AE H2A.1, H2A/a, H2AFA ENSG00000277075 Histone cluster 1 H2A family member e 6 26216975-26217483 Predicted intracellular proteins Evidence at protein level CAB012242, HPA041189 Supported Supported Nucleoplasm Expressed in all Tissue enhanced breast: 54.1 prostate: 21.5 Cell line enhanced U-266/70: 28.2 +CH507-9B2.1 ENSG00000277117 21 5022493-5040666 Predicted membrane proteins Evidence at protein level HPA029179 Supported Plasma membrane
Cytoplasmic bodies Mixed Mixed cerebral cortex: 11.2 Cell line enhanced BEWO: 20.4;REH: 15.6;SiHa: 15.3 +TYW1B LINC00069, MGC87315, NCRNA00069, RSAFD2 ENSG00000277149 TRNA-yW synthesizing protein 1 homolog B 7 72558744-72828198 Predicted membrane proteins Evidence at protein level HPA013568, HPA014118, HPA043136, HPA047029, HPA047052, HPA052097 Approved Approved Nucleus
Nucleoli Expressed in all Mixed ovary: 6.7 Mixed +F8A3 ENSG00000277150 Coagulation factor VIII-associated 3 X 155456914-155458672 Predicted intracellular proteins Evidence at protein level HPA046960 Uncertain Not detected Tissue enhanced parathyroid gland: 32.9 cerebral cortex: 10.5 Cell line enhanced U-266/70: 31.3;U-266/84: 28.7 +HIST1H4D H4/b, H4FB ENSG00000277157 Histone cluster 1 H4 family member d 6 26188765-26189076 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Mixed Mixed fallopian tube: 1.7 Cell line enhanced HEK 293: 8.2;RT4: 11.7 +PIGW FLJ37433, Gwt1 ENSG00000277161 Phosphatidylinositol glycan anchor biosynthesis class W 17 36535020-36539310 Disease related genes, Predicted membrane proteins Evidence at protein level HPA023499 Approved Plasma membrane Expressed in all Mixed appendix: 5.1 Expressed in all +AC007325.2 ENSG00000277196 Unmapped 138082-161852 Predicted intracellular proteins Evidence at transcript level HPA020361 Uncertain Tissue enhanced skin: 38.5;small intestine: 37.1 duodenum: 29.0 Cell line enriched 7 RPTEC TERT1: 137.9 +F8A1 DXS522E, F8A ENSG00000277203 Coagulation factor VIII-associated 1 X 154886349-154888061 Predicted intracellular proteins Evidence at protein level HPA046960 Uncertain Cervical cancer:1.67e-6 (favourable) Expressed in all Expressed in all thyroid gland: 30.2 Mixed +HIST1H2BF H2B/g, H2BFG ENSG00000277224 Histone cluster 1 H2B family member f 6 26199520-26200715 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed Tissue enhanced esophagus: 3.5;prostate: 2.6 breast: 2.2 Cell line enhanced U-266/70: 18.9;U-266/84: 13.1 +PCGF2 MEL-18, RNF110, ZNF144 ENSG00000277258 Polycomb group ring finger 2 17 38733897-38749817 Predicted intracellular proteins Evidence at protein level HPA047732, HPA063531 Uncertain Supported Nucleus Colorectal cancer:4.55e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 20.1 Mixed +CH507-396I9.7 ENSG00000277277 21 7768884-7770591 Predicted intracellular proteins Evidence at transcript level HPA045123 Uncertain Not detected Mixed cerebral cortex: 3.0 Mixed +C10orf142 ENSG00000277288 Chromosome 10 open reading frame 142 10 44292569-44294649 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced testis: 2.3 spleen: 1.5 Cell line enhanced RPMI-8226: 1.6;U-2197: 5.2;U-87 MG: 2.0 +GOLGA6L6 FLJ36131 ENSG00000277322 Golgin A6 family-like 6 15 20531856-20541800 Predicted intracellular proteins Evidence at transcript level HPA047733 Uncertain Not detected Tissue enriched 41 testis: 4.1 all non-specific tissues: 0.0 Not detected +SRCIN1 KIAA1684, p140Cap, SNIP ENSG00000277363 SRC kinase signaling inhibitor 1 17 38530016-38605930 Predicted intracellular proteins Evidence at protein level HPA009701, HPA063795 Enhanced Approved Cell Junctions Urothelial cancer:1.76e-4 (favourable) Mixed Tissue enhanced cerebral cortex: 22.1 skin: 4.7 Cell line enriched 5 SCLC-21H: 14.7 +GPR179 CSNB1E, GPR158L1 ENSG00000277399 G protein-coupled receptor 179 17 38325530-38343847 Predicted membrane proteins No evidence HPA017885 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +AC145212.2 ENSG00000277400 MaFF-interacting protein Unmapped 53590-115018 Predicted secreted proteins Evidence at protein level Mixed ovary: 8.1 Mixed +MARCKS 80K-L, MACS, PKCSL ENSG00000277443 Myristoylated alanine rich protein kinase C substrate 6 113857362-113863471 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022062, HPA054820, HPA067595, HPA069443 Enhanced Approved Nucleus
Endoplasmic reticulum
Plasma membrane
Cytosol Liver cancer:2.78e-8 (unfavourable), Renal cancer:4.85e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 218.8 Cell line enhanced AF22: 402.5 +ZNF670 MGC12466 ENSG00000277462 Zinc finger protein 670 1 247036784-247078755 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003142 Uncertain Approved Nucleus
Cytosol Expressed in all Mixed testis: 6.1 Expressed in all +AC213203.1 ENSG00000277475 Unmapped 31698-32528 Predicted membrane proteins Evidence at transcript level Tissue enriched 11 testis: 24.2 lung: 2.2 Cell line enhanced A549: 6.4;HMC-1: 4.8;SCLC-21H: 5.4 +PKD1L3 ENSG00000277481 Polycystin 1 like 3, transient receptor potential channel interacting 16 71929538-71999978 Predicted membrane proteins, Transporters Evidence at protein level Not detected Not detected testis: 0.7 Not detected +GPIHBP1 GPI-HBP1, LOC338328 ENSG00000277494 Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 8 143213193-143217170 Disease related genes, Predicted secreted proteins Evidence at protein level HPA066302 Enhanced Mixed Group enriched 6 adipose tissue: 94.2;lung: 33.0 skeletal muscle: 10.5 Cell line enhanced Karpas-707: 2.3 +LLNLF-187D8.1 ENSG00000277531 19 46424697-46428951 Predicted intracellular proteins Evidence at transcript level Tissue enriched Tissue enriched 9 cerebral cortex: 23.3 epididymis: 2.5 Group enriched 5 AF22: 1.1;HMC-1: 2.2;SH-SY5Y: 4.0 +RP13-347D8.7 ENSG00000277535 X 119073226-119076373 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 76 testis: 7.6 all non-specific tissues: 0.0 Not detected +OR13C5 ENSG00000277556 Olfactory receptor family 13 subfamily C member 5 9 104598457-104599413 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected adrenal gland,fallopian tube,seminal vesicle,testis,thyroid gland: 0.1 Not detected +NEFL CMT1F, CMT2E, NF68, NFL, PPP1R110 ENSG00000277586 Neurofilament light 8 24950955-24957110 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA014850, HPA015021 Enhanced Supported Approved Nuclear speckles
Intermediate filaments Renal cancer:4.91e-4 (unfavourable) Tissue enhanced Tissue enriched 10 cerebral cortex: 289.3 adrenal gland: 29.0 Cell line enhanced HEK 293: 544.8;PC-3: 147.7 +BX072566.1 ENSG00000277630 Uncharacterized protein LOC100288966 Unmapped 108007-139659 Predicted intracellular proteins Evidence at transcript level HPA042822 Uncertain Tissue enriched 74 testis: 7.4 all non-specific tissues: 0.0 Not detected +CCL3 G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3 ENSG00000277632 C-C motif chemokine ligand 3 17 36088256-36090169 Cancer-related genes, Predicted secreted proteins Evidence at protein level Expressed in all Tissue enhanced bone marrow: 50.2 adipose tissue: 12.5 Group enriched 14 Karpas-707: 110.0;U-266/70: 198.4;U-266/84: 494.6 +RP11-467J12.4 ENSG00000277639 16 53035690-53052873 Predicted intracellular proteins Evidence at transcript level Tissue enhanced Tissue enriched 7 fallopian tube: 124.4 cervix, uterine: 18.1 Cell line enhanced BEWO: 11.2 +AC136352.2 ENSG00000277666 Unmapped 100123-101141 Predicted secreted proteins Evidence at protein level HPA003342 Uncertain Not detected all non-specific tissues: 0.0 Not detected +AC009133.22 ENSG00000277669 16 29663279-29695144 Predicted secreted proteins Evidence at protein level HPA011887 Uncertain Not detected Tissue enhanced colon: 2.6;duodenum: 1.8;spleen: 1.0 lung: 0.4 Cell line enhanced BEWO: 44.0;EFO-21: 114.1;SH-SY5Y: 19.3 +RP4-635E18.9 ENSG00000277726 1 11012662-11030528 Predicted intracellular proteins Evidence at transcript level Not detected Mixed epididymis: 3.0 Cell line enhanced Hep G2: 2.1;MCF7: 1.1;RT4: 1.6 +H2AFB3 H2AFB ENSG00000277745 H2A histone family member B3 X 155459415-155460005 Predicted intracellular proteins Evidence at protein level Not detected Tissue enriched 56 testis: 18.5 spleen: 0.3 Cell line enriched 7 HDLM-2: 8.3 +ABC7-42404400C24.1 ENSG00000277758 10 47750864-47763592 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA036971, HPA036972, HPA064559 Approved Approved Golgi apparatus Not detected Tissue enhanced cerebral cortex: 13.8;lung: 19.3 skin: 5.7 Cell line enriched 7 SK-BR-3: 45.1 +AC136616.2 ENSG00000277761 Unmapped 1167457-1257196 Predicted intracellular proteins Evidence at transcript level Mixed colon: 76.7 Not detected +HIST1H3F H3/i, H3FI ENSG00000277775 Histone cluster 1 H3 family member f 6 26250195-26250605 Predicted intracellular proteins Evidence at protein level HPA042570, CAB070190 Supported Mixed Tissue enhanced bone marrow: 1.4 lymph node: 0.7 Cell line enhanced U-266/84: 4.6 +PSMB3 HC10-II, MGC4147 ENSG00000277791 Proteasome subunit beta 3 17 38752736-38764231 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042775, HPA048147 Approved Enhanced Mitochondria Renal cancer:1.71e-6 (unfavourable) Expressed in all Expressed in all epididymis: 83.6 Expressed in all +AC141272.1 ENSG00000277836 Unmapped 1270984-1271271 Predicted intracellular proteins Evidence at transcript level Tissue enhanced tonsil: 114.8 urinary bladder: 94.9 Cell line enhanced RPMI-8226: 1.3 +AC233755.2 ENSG00000277856 Unmapped 26241-26534 Predicted intracellular proteins Evidence at transcript level Tissue enhanced tonsil: 197.2 lymph node: 99.3 Cell line enhanced MOLT-4: 6.1;REH: 2.1;SH-SY5Y: 2.5;TIME: 1.3 +H2AFB2 ENSG00000277858 H2A histone family member B2 X 155380787-155381134 Predicted intracellular proteins Evidence at protein level Not detected Not detected duodenum: 0.6 Not detected +GOLGA6L22 ENSG00000277865 Golgin A6 family-like 22 15 22458903-22469230 Predicted intracellular proteins Evidence at transcript level HPA047733 Uncertain Not detected Tissue enriched 19 testis: 5.2 cerebral cortex,skin: 0.2 Not detected +FAM230A DGCR15 ENSG00000277870 Family with sequence similarity 230 member A 22 18422244-18500594 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 26 testis: 24.1 stomach: 0.9 Cell line enhanced A549: 16.6;U-266/84: 10.9 +SRD5A2 ENSG00000277893 Steroid 5 alpha-reductase 2 2 31522480-31581067 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Group enriched Group enriched 11 epididymis: 27.9;fallopian tube: 31.6;liver: 30.6;prostate: 26.6;seminal vesicle: 24.5 testis: 2.5 Cell line enhanced RT4: 1.2 +OR52E5 ENSG00000277932 Olfactory receptor family 52 subfamily E member 5 11 5900777-5902090 G-protein coupled receptors, Predicted membrane proteins No evidence Not detected Not detected testis: 0.1 Not detected +CISD3 Miner2 ENSG00000277972 CDGSH iron sulfur domain 3 17 38730235-38735044 Predicted intracellular proteins Evidence at protein level HPA053436, HPA054400 Approved Expressed in all Mixed thyroid gland: 8.5 Mixed +RDM1 MGC33977, RAD52B ENSG00000278023 RAD52 motif containing 1 17 35918066-35930773 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024794, HPA067546 Enhanced Supported Nucleoli
Cytosol Mixed Tissue enriched 6 testis: 9.7 tonsil: 1.6 Cell line enhanced T-47d: 17.4 +DDX52 ROK1 ENSG00000278053 DExD-box helicase 52 17 37609739-37643464 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056173 Uncertain Supported Nucleus
Nucleoli Liver cancer:2.44e-6 (unfavourable), Colorectal cancer:9.41e-4 (favourable) Expressed in all Mixed epididymis: 4.6 Mixed +TEX28 CXorf2, fTEX ENSG00000278057 Testis expressed 28 X 154271265-154295853 Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 33 testis: 6.2 bone marrow,skin: 0.1 Not detected +CT45A8 ENSG00000278085 Cancer/testis antigen family 45 member A8 X 135846499-135854538 Predicted intracellular proteins Evidence at protein level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Not detected Tissue enriched 12 testis: 1.2 all non-specific tissues: 0.0 Group enriched 6 AN3-CA: 18.9;HMC-1: 39.4 +ZNF8 HF.18, Zfp128 ENSG00000278129 Zinc finger protein 8 19 58278951-58302805 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034797, HPA034798 Uncertain Approved Nucleoplasm
Nuclear bodies Mixed Mixed parathyroid gland: 4.5 Mixed +RP4-533D7.6 ENSG00000278139 1 46043661-46176488 Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level HPA005751 Uncertain Not detected Tissue enriched 30 testis: 41.3 gallbladder: 1.3 Cell line enhanced HeLa: 2.1;RT4: 8.4 +SSTR3 ENSG00000278195 Somatostatin receptor 3 22 37204238-37212322 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB022647 Approved Tissue enhanced Tissue enhanced testis: 10.9 cerebral cortex: 3.9 Group enriched 12 RPMI-8226: 16.5;SCLC-21H: 10.1 +AC011043.2 ENSG00000278198 Unmapped 173872-179372 Predicted intracellular proteins Evidence at transcript level Not detected skin: 0.4 Cell line enhanced A-431: 2.4 +PRICKLE4 C6orf49, DKFZp761H221, OEBT ENSG00000278224 Prickle planar cell polarity protein 4 6 41780762-41787372 Predicted intracellular proteins Evidence at transcript level HPA031240 Uncertain Mitotic spindle
Microtubule organizing center Not detected Mixed fallopian tube: 3.9 Cell line enhanced BEWO: 3.9 +MYO19 FLJ22865, MYOHD1 ENSG00000278259 Myosin XIX 17 36495633-36543435 Predicted intracellular proteins Evidence at protein level HPA021415, HPA059715 Approved Enhanced Cytosol Liver cancer:8.33e-6 (unfavourable) Expressed in all Expressed in all skin: 14.5 Expressed in all +HIST1H3C H3.1, H3/c, H3FC ENSG00000278272 Histone cluster 1 H3 family member c 6 26045411-26045821 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Mixed Tissue enhanced bone marrow: 3.3 testis: 1.3 Cell line enhanced U-937: 6.7 +CT45A6 CT45-6, CT45.6 ENSG00000278289 Cancer/testis antigen family 45 member A6 X 135794706-135802656 Predicted intracellular proteins Evidence at protein level HPA044735, HPA044757, HPA046872, HPA046987 Supported Approved Nucleus
Nucleoli Not detected Not detected testis: 0.7 Cell line enriched 7 U-266/84: 72.2 +TBC1D3C MGC44903 ENSG00000278299 TBC1 domain family member 3C 17 38057693-38068592 Predicted membrane proteins Evidence at protein level HPA046969, HPA047745, HPA052553 Approved Uncertain Vesicles Not detected Tissue enhanced testis: 3.3 skin: 2.1 Cell line enhanced CAPAN-2: 30.1;HeLa: 4.4;T-47d: 6.5 +GGNBP2 DIF-3, DIF3, FLJ21230, FLJ22561, LZK1, ZFP403, ZNF403 ENSG00000278311 Gametogenetin binding protein 2 17 36544888-36589848 Predicted intracellular proteins Evidence at protein level HPA018914, HPA073392 Approved Approved Endoplasmic reticulum Expressed in all Expressed in all testis: 55.7 Expressed in all +ZNF229 ENSG00000278318 Zinc finger protein 229 19 44417519-44448578 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA001494 Uncertain Approved Vesicles
Plasma membrane Renal cancer:8.43e-5 (favourable) Mixed Tissue enhanced parathyroid gland: 6.7 fallopian tube,thyroid gland: 3.1 Mixed +AL354822.1 ENSG00000278384 Unmapped 51867-54893 Predicted intracellular proteins Evidence at transcript level Mixed skin: 3.4 Mixed +HIST1H2AB H2A/m, H2AFM ENSG00000278463 Histone cluster 1 H2A family member b 6 26033176-26033568 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Mixed Tissue enhanced bone marrow: 1.6 lymph node,testis: 0.6 Cell line enhanced Hep G2: 3.4 +RP11-457D20.2 ENSG00000278499 Putative UPF0607 protein ENSP00000381418 16 60358455-60359480 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 17 testis: 4.3 skeletal muscle: 0.2 Not detected +C17orf78 FLJ39647 ENSG00000278505 Chromosome 17 open reading frame 78 17 37375986-37392708 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Group enriched Group enriched 74 duodenum: 99.1;small intestine: 50.9 testis: 1.0 Not detected +POTEB3 ENSG00000278522 POTE ankyrin domain family member B3 15 21408243-21440451 Predicted intracellular proteins Evidence at transcript level HPA042822 Uncertain Not detected Tissue enriched 22 testis: 2.2 all non-specific tissues: 0.0 Not detected +DHRS11 MGC4172, SDR24C1 ENSG00000278535 Dehydrogenase/reductase 11 17 36591798-36600806 Predicted intracellular proteins Evidence at protein level HPA041226, HPA048236, HPA053623 Enhanced Approved Golgi apparatus
Cytosol Renal cancer:3.24e-4 (favourable) Expressed in all Group enriched 8 colon: 44.6;duodenum: 149.5;rectum: 47.1;small intestine: 133.6 testis: 11.8 Mixed +ACACA ACAC, ACC, ACC1 ENSG00000278540 Acetyl-CoA carboxylase alpha 17 37084988-37406818 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB013715, HPA036650, HPA063018 Approved Supported Nucleoli fibrillar center
Actin filaments
Cytosol Liver cancer:1.24e-5 (unfavourable) Expressed in all Mixed breast: 28.8 Expressed in all +TMEM191B ENSG00000278558 Transmembrane protein 191B 22 18527802-18530573 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Not detected Tissue enriched 15 testis: 14.7 spleen: 0.9 Cell line enhanced BEWO: 1.4;CACO-2: 1.0 +OR4F29 ENSG00000278566 Olfactory receptor family 4 subfamily F member 29 1 450740-451678 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA047705 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +NR2E3 PNR, rd7, RP37 ENSG00000278570 Nuclear receptor subfamily 2 group E member 3 15 71792638-71818259 Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Not detected prostate: 0.7 Not detected +HIST1H2BI H2B/k, H2BFK ENSG00000278588 Histone cluster 1 H2B family member i 6 26272976-26273356 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Mixed Tissue enhanced bone marrow: 1.9;lymph node: 1.7 testis,urinary bladder: 0.7 Cell line enhanced MOLT-4: 10.0 +TBC1D3E ENSG00000278599 TBC1 domain family member 3E 17 38127951-38138862 Predicted membrane proteins Evidence at protein level HPA046969, HPA047745, HPA052553 Approved Uncertain Vesicles Not detected Tissue enhanced bone marrow: 1.1;gallbladder: 1.8;testis: 3.1 lymph node: 0.9 Cell line enhanced HHSteC: 3.4 +C11orf98 C11orf48 ENSG00000278615 Chromosome 11 open reading frame 98 11 62662816-62665217 Predicted intracellular proteins Evidence at transcript level Renal cancer:4.02e-6 (unfavourable), Liver cancer:5.85e-5 (unfavourable), Endometrial cancer:7.62e-4 (unfavourable) Expressed in all Expressed in all lymph node: 80.3 Expressed in all +MRM1 FLJ22578 ENSG00000278619 Mitochondrial rRNA methyltransferase 1 17 36601572-36608971 Predicted intracellular proteins Evidence at protein level HPA021598 Supported Enhanced Mitochondria Expressed in all Mixed adrenal gland: 5.0 Mixed +AC023491.2 ENSG00000278633 Unmapped 10598-13001 Predicted intracellular proteins Evidence at transcript level Tissue enriched 545 testis: 67.4 parathyroid gland,small intestine: 0.1 Not detected +HIST1H4A H4FA ENSG00000278637 Histone cluster 1 H4 family member a 6 26021679-26021990 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB021887, HPA042201 Supported Mixed Mixed appendix: 1.9 Cell line enhanced MOLT-4: 11.9;REH: 12.2 +RP1-321E8.5 ENSG00000278646 X 120877496-120878924 Predicted intracellular proteins Evidence at protein level HPA042483 Supported Not detected Tissue enriched 8 testis: 3.3 adrenal gland: 0.4 Cell line enhanced U-266/70: 2.9 +GOLGA6L10 GOLGA6L18 ENSG00000278662 Golgin A6 family-like 10 15 82339998-82349475 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 7 testis: 8.7 ovary,skin: 1.2 Cell line enhanced HEK 293: 3.0;SK-MEL-30: 1.3 +ELOA3B HsT828, TCEB3CL ENSG00000278674 Elongin A3 family member B 18 47022287-47023927 Predicted intracellular proteins No evidence HPA048971, HPA049178, HPA050086 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +HIST1H2AM H2A.1, H2A/n, H2AFN ENSG00000278677 Histone cluster 1 H2A family member m 6 27892757-27893149 Predicted intracellular proteins Evidence at protein level HPA041189 Supported Mixed Mixed bone marrow,lymph node: 2.6 Cell line enhanced U-266/84: 26.9 +IQCA1L IQCA1P1, TCAG_9762 ENSG00000278685 IQ motif containing with AAA domain 1 like 7 151190873-151205496 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enriched 41 testis: 4.0 all non-specific tissues: 0.0 Not detected +BX004987.1 ENSG00000278704 Unmapped 56140-58376 Predicted intracellular proteins Evidence at transcript level Mixed testis: 3.3 Cell line enhanced K-562: 22.1;U-2 OS: 18.2 +HIST1H4B H4/I, H4FI ENSG00000278705 Histone cluster 1 H4 family member b 6 26026815-26027252 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042201 Supported Mixed Tissue enhanced bone marrow: 1.3 lymph node: 0.8 Mixed +AC136616.3 ENSG00000278782 Unmapped 1157687-1240349 Predicted intracellular proteins Evidence at transcript level Tissue enhanced cervix, uterine: 8.6;tonsil: 6.6 breast,small intestine: 5.4 Not detected +AC007325.4 ENSG00000278817 Unmapped 131494-137392 Predicted intracellular proteins Evidence at transcript level Tissue enhanced cerebral cortex: 27.4;heart muscle: 34.4;skeletal muscle: 40.5 thyroid gland: 14.9 Cell line enhanced A549: 14.5;T-47d: 10.8 +HIST1H3H H3/k, H3F1K, H3FK ENSG00000278828 Histone cluster 1 H3 family member h 6 27810064-27811300 Predicted intracellular proteins Evidence at protein level HPA042570 Supported Pancreatic cancer:9.25e-6 (unfavourable), Renal cancer:5.73e-5 (unfavourable), Cervical cancer:4.35e-4 (favourable) Expressed in all Mixed rectum: 2.9 Cell line enhanced K-562: 30.1;SiHa: 30.0;U-266/84: 42.9 +MRPL45 MGC11321 ENSG00000278845 Mitochondrial ribosomal protein L45 17 38297023-38323218 Predicted intracellular proteins Evidence at protein level HPA023373, HPA023385 Enhanced Enhanced Mitochondria Expressed in all Mixed endometrium: 10.2 Cell line enhanced AF22: 27.5;Daudi: 49.3;K-562: 38.3;REH: 31.0;U-266/84: 28.8;U-698: 34.9 +TP53TG3F ENSG00000278848 TP53 target 3 family member F 16 33459045-33462249 Predicted intracellular proteins Evidence at transcript level Not detected Group enriched 14 epididymis: 7.4;testis: 4.2 placenta: 0.4 Cell line enhanced HEL: 1.0 +OR2S2 ENSG00000278889 Olfactory receptor family 2 subfamily S member 2 (gene/pseudogene) 9 35957108-35958154 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +CH507-396I9.3 ENSG00000278961 21 7788703-7793954 Predicted membrane proteins Evidence at transcript level HPA029085 Uncertain Not detected Group enriched 7 breast: 1.5;fallopian tube: 1.4;kidney: 4.3 skin: 0.3 Not detected +OR6Q1 ENSG00000279051 Olfactory receptor family 6 subfamily Q member 1 (gene/pseudogene) 11 58030930-58031931 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +CH17-140K24.5 ENSG00000279068 5 141182409-141188582 Predicted intracellular proteins Evidence at transcript level Not detected Mixed endometrium: 1.6 Cell line enhanced AN3-CA: 5.5;RH-30: 3.5;U-138 MG: 7.2;U-2197: 4.5 +FAM231C ENSG00000279132 Family with sequence similarity 231 member C 1 16733952-16734461 Predicted intracellular proteins No evidence HPA043267, HPA043292 Uncertain Not detected Not detected testis: 0.1 Not detected +PRAMEF13 ENSG00000279169 PRAME family member 13 1 13196330-13201409 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.1 Not detected +RP11-294C11.3 ENSG00000279408 15 21651844-21653039 Predicted membrane proteins Evidence at transcript level HPA057442 Uncertain Uncertain Centrosome Not detected Tissue enriched 17 testis: 14.6 cerebral cortex: 0.8 Cell line enriched 42 U-2 OS: 6.9 +OR2AG1 OR2AG3 ENSG00000279486 Olfactory receptor family 2 subfamily AG member 1 (gene/pseudogene) 11 6785017-6786014 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Not detected Not detected all non-specific tissues: 0.0 Not detected +CH507-9B2.2 ENSG00000279493 21 5011799-5017145 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced kidney: 1.8;liver: 2.7 lymph node: 0.5 Cell line enhanced BEWO: 1.3;CACO-2: 2.4;MCF7: 1.6;SiHa: 3.5 +RP11-437B10.1 ENSG00000279765 15 92883413-92949230 Predicted intracellular proteins Evidence at transcript level Not detected Expressed in all bone marrow: 243.6 Mixed +AL513523.2 ENSG00000279767 1 153772371-153774079 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced lymph node: 1.4;skin: 3.5 cerebral cortex,lung: 0.8 Cell line enhanced MCF7: 7.6;SK-BR-3: 5.9;THP-1: 5.5 +PPIAL4F ENSG00000279782 Peptidylprolyl isomerase A like 4F 1 144592868-144593527 Enzymes, Predicted intracellular proteins No evidence HPA058345 Uncertain Not detected Not detected all non-specific tissues: 0.0 Not detected +PRAMEF18 ENSG00000279804 PRAME family member 18 1 13222705-13226106 Predicted intracellular proteins No evidence HPA057423 Uncertain Not detected Not detected bone marrow: 0.1 Not detected +GVQW2 ENSG00000279968 GVQW motif containing 2 6 138725211-138773652 Predicted intracellular proteins Evidence at transcript level Mixed Tissue enhanced testis: 2.3 epididymis,thyroid gland: 0.5 Cell line enhanced HEL: 1.9 +CH17-140K24.8 ENSG00000279983 5 141223372-141245861 Predicted intracellular proteins Evidence at transcript level Not detected Tissue enhanced epididymis: 1.5 endometrium: 0.8 Not detected +CH507-9B2.3 ENSG00000280071 21 5079294-5128425 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018517 Uncertain Approved Centrosome
Mitochondria Mixed Expressed in all kidney: 148.3 Mixed +OR8B4 OR8B4P ENSG00000280090 Olfactory receptor family 8 subfamily B member 4 (gene/pseudogene) 11 124423904-124424893 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Not detected Not detected all non-specific tissues: 0.0 Not detected +PCDH20 FLJ22218, PCDH13 ENSG00000280165 Protocadherin 20 13 61409685-61415522 Predicted membrane proteins Evidence at protein level HPA062669 Approved Vesicles
Cytokinetic bridge Not detected Tissue enhanced cerebral cortex: 14.5;smooth muscle: 13.0 lung: 5.0 Cell line enriched 12 RPTEC TERT1: 39.0 +PRAMEF26 ENSG00000280267 PRAME family member 26 1 13148905-13155961 Predicted intracellular proteins No evidence Not detected Not detected all non-specific tissues: 0.0 Not detected +CH507-9B2.9 ENSG00000280433 21 5155499-5165472 Predicted intracellular proteins Evidence at transcript level Mixed Mixed lymph node: 13.6 Mixed +CCDC163 C1orf231, CCDC163P, LOC126661 ENSG00000280670 Coiled-coil domain containing 163 1 45493866-45500079 Predicted membrane proteins Evidence at transcript level Thyroid cancer:5.05e-4 (unfavourable) Expressed in all Tissue enhanced parathyroid gland: 2.3 thyroid gland: 1.5 Cell line enhanced U-266/70: 5.1 +CH17-270A2.2 ENSG00000280778 1 145927258-145977811 Predicted intracellular proteins No evidence Not detected Not detected testis: 0.2 Not detected +PAGR1 C16orf53, GAS, MGC4606, PA1 ENSG00000280789 PAXIP1 associated glutamate rich protein 1 16 29815952-29820117 Predicted intracellular proteins Evidence at protein level HPA041440, HPA043608 Uncertain Expressed in all Expressed in all ovary: 60.4 Expressed in all +RPS4Y2 RPS4Y2P ENSG00000280969 Ribosomal protein S4, Y-linked 2 Y 20756164-20781032 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA000857 Uncertain Tissue enriched Group enriched 13 prostate: 3.5;testis: 2.2 tonsil: 0.2 Cell line enriched 7 U-266/84: 1.3 +MATR3 ENSG00000280987 Matrin 3 5 139273752-139331671 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036564, HPA036565 Supported Approved Nucleoplasm Not detected Expressed in all cerebral cortex: 48.4 Expressed in all +RP11-717K11.2 ENSG00000281028 4 25160663-25277306 Predicted intracellular proteins Evidence at protein level HPA004099 Uncertain Uncertain Cytosol Not detected Mixed testis: 11.3 Mixed +RP4-777O23.3 ENSG00000281039 7 30497077-30550761 Predicted intracellular proteins Evidence at protein level HPA020735 Uncertain Not detected Mixed epididymis: 30.5 Mixed +LINC00282 FLJ37307, NCRNA00282 ENSG00000281106 Long intergenic non-protein coding RNA 282 13 51813347-51845175 Predicted membrane proteins Evidence at transcript level Not detected Mixed lymph node: 3.3 Cell line enhanced BEWO: 1.0;SK-MEL-30: 2.7 +RP11-506B6.7 ENSG00000281613 6 112236806-112350094 Predicted intracellular proteins Evidence at transcript level HPA059324 Uncertain Not detected Tissue enriched 14 testis: 8.2 placenta: 0.6 Cell line enriched 12 RPTEC TERT1: 2.7 +GIMAP1-GIMAP5 ENSG00000281887 GIMAP1-GIMAP5 readthrough 7 150716668-150743646 Predicted membrane proteins Evidence at protein level HPA053441 Supported Endoplasmic reticulum Not detected Tissue enhanced spleen: 17.9 appendix: 14.9 Group enriched 9 HUVEC TERT2: 5.3;MOLT-4: 8.3;THP-1: 1.7;TIME: 3.9 +AL359736.1 ENSG00000281899 13 24321126-24321428 Predicted intracellular proteins No evidence Not detected Not detected esophagus: 0.4 Not detected +TMEM265 ENSG00000281991 Transmembrane protein 265 16 30740381-30744281 Predicted membrane proteins Evidence at transcript level Mixed skin: 18.9 Cell line enhanced CAPAN-2: 79.5;T-47d: 46.9 +RP1-179P9.3 ENSG00000282218 6 117318211-117573571 Predicted intracellular proteins Evidence at transcript level HPA019477 Uncertain Approved Golgi apparatus
Cytosol Not detected epididymis,lung: 0.8 Cell line enriched 47 U-138 MG: 8.8 +RP11-295P9.13 ENSG00000282246 10 13610047-13655929 Predicted intracellular proteins Evidence at protein level HPA047950 Uncertain Mixed skin: 14.3 Mixed +RP11-231C18.3 ENSG00000282278 4 53377839-54295272 Predicted intracellular proteins Evidence at protein level HPA058202 Tissue enhanced appendix: 1.2;cerebral cortex: 3.3 ovary,smooth muscle: 0.7 Cell line enhanced BJ hTERT+: 2.8;fHDF/TERT166: 6.4;HDLM-2: 2.1;NTERA-2: 1.8;U-2197: 1.7 +CYP3A7-CYP3A51P ENSG00000282301 CYP3A7-CYP3A51P readthrough 7 99684957-99735102 Enzymes, Predicted membrane proteins Evidence at protein level HPA072245 Uncertain Cytosol Tissue enhanced liver: 7.4 gallbladder: 1.9 Not detected +TEX13D ENSG00000282419 TEX13 family member D X 124246249-124336862 Predicted intracellular proteins Evidence at transcript level Tissue enriched 33 testis: 3.2 all non-specific tissues: 0.0 Not detected +ADORA3 AD026 ENSG00000282608 Adenosine A3 receptor 1 111499429-111503760 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Mixed adrenal gland: 18.4 Cell line enriched 12 HMC-1: 89.3 +DUXB ENSG00000282757 Double homeobox B 16 75693929-75701459 Predicted intracellular proteins No evidence Not detected testis,thyroid gland: 0.3 Not detected +RP3-369A17.6 ENSG00000282804 6 24797373-24809798 Predicted intracellular proteins No evidence Not detected appendix: 0.5 Not detected +TEX13C ENSG00000282815 TEX13 family member C X 125320120-125325214 Predicted intracellular proteins Evidence at protein level Tissue enriched 28 testis: 2.8 all non-specific tissues: 0.0 Not detected +RP13-794C1.1 ENSG00000282827 3 48446846-48467645 Predicted intracellular proteins Evidence at transcript level Tissue enhanced testis: 1.3 thyroid gland: 0.6 Cell line enhanced AF22: 1.8;NTERA-2: 1.4;RT4: 2.2 +RP11-96L14.8 ENSG00000282872 1 26164161-26168581 Predicted intracellular proteins Evidence at transcript level Not detected testis: 0.6 Cell line enriched 10 SCLC-21H: 4.0 +RP11-49P4.7 ENSG00000282881 1 46532166-46533614 Predicted membrane proteins No evidence Not detected cerebral cortex: 0.3 Not detected +CTC-281F24.5 ENSG00000282936 17 6636780-6640316 Predicted intracellular proteins Evidence at transcript level Mixed cerebral cortex: 1.9 Mixed +HIST1H3D H3/b, H3FB ENSG00000282988 Histone cluster 1 H3 family member d 6 26195595-26199293 Predicted intracellular proteins Evidence at transcript level HPA041189 Uncertain Tissue enhanced bone marrow: 2.1 prostate,testis: 0.7 Cell line enhanced K-562: 5.4;SiHa: 5.8;U-266/70: 5.2 +KLF18 ENSG00000283039 Kruppel like factor 18 1 44137821-44141631 Predicted intracellular proteins No evidence Not detected testis: 0.2 Not detected +RP11-736N17.11 ENSG00000283071 Homo sapiens translation initiation factor IF-2-like (LOC107984640), mRNA. 14 103084210-103090027 Predicted intracellular proteins Evidence at transcript level Tissue enhanced testis: 1.0 cerebral cortex: 0.5 Not detected +CTD-2331H12.8 ENSG00000283088 19 52880663-52962768 Predicted intracellular proteins Evidence at transcript level HPA062474 Uncertain Nucleoplasm
Cytoplasmic bodies Mixed parathyroid gland: 7.1 Cell line enhanced RT4: 18.8 +CENPVL2 CENPVP2 ENSG00000283093 Centromere protein V like 2 X 51681212-51682831 Predicted intracellular proteins Evidence at transcript level Tissue enhanced testis: 3.0 cerebral cortex: 0.8 Cell line enhanced NTERA-2: 2.1;PC-3: 4.2;U-2 OS: 3.6 +RP11-134F2.8 ENSG00000283149 3 186581995-186597103 Predicted intracellular proteins Evidence at protein level HPA010814 Uncertain Uncertain Endoplasmic reticulum Mixed epididymis: 36.6 Mixed +IQCJ-SCHIP1 ENSG00000283154 IQCJ-SCHIP1 readthrough 3 158962235-159897366 Predicted intracellular proteins Evidence at protein level HPA003243, HPA003445 Approved Approved Cytosol Tissue enhanced cerebral cortex: 99.0 smooth muscle: 36.8 Mixed +RP11-949J7.8 ENSG00000283189 3 49416777-49429314 Predicted intracellular proteins No evidence Not detected duodenum,lung: 0.2 Not detected +ABC13-47488600E17.1 ENSG00000283199 13 113953705-113973997 Predicted intracellular proteins Evidence at transcript level Tissue enhanced stomach: 2.6;testis: 5.9 lung: 2.1 Cell line enhanced hTEC/SVTERT24-B: 1.2 +RP11-15H20.8 ENSG00000283201 19 23222755-23274221 Predicted intracellular proteins Evidence at transcript level Mixed epididymis: 4.5 Mixed +RP11-350E12.6 ENSG00000283205 9 87956214-87956883 Predicted intracellular proteins Evidence at transcript level Tissue enriched 40 testis: 7.3 cervix, uterine: 0.1 Not detected +RP11-226E21.4 ENSG00000283208 13 76992078-77129589 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Tissue enhanced bone marrow: 2.8 cerebral cortex,thyroid gland: 0.9 Not detected +RP1-20N18.10 ENSG00000283227 1 152947154-152949258 Predicted intracellular proteins Evidence at transcript level Tissue enriched 8 skin: 50.7 breast: 6.5 Group enriched 9 HaCaT: 1.8;hTCEpi: 3.8 +RP11-638I8.1 ENSG00000283247 7 45860008-45873082 Predicted intracellular proteins Evidence at transcript level Tissue enhanced placenta: 1.2 breast: 0.8 Not detected +CTB-16J4.1 ENSG00000283267 7 90316503-90321308 Predicted secreted proteins No evidence Not detected testis: 0.4 Not detected +RP11-727F15.14 ENSG00000283268 11 62832319-62832803 Predicted intracellular proteins Evidence at transcript level Tissue enriched 34 testis: 40.8 thyroid gland: 1.2 Not detected +AC138517.6 ENSG00000283288 5 139470778-139474772 Predicted membrane proteins Evidence at transcript level Tissue enhanced rectum: 2.6 colon: 1.6 Not detected +RP4-816N1.8 ENSG00000283297 Uncharacterized protein ENSP00000372125 12 2849039-2857083 Predicted intracellular proteins Evidence at transcript level Tissue enhanced skin: 4.3;testis: 7.4 appendix,lymph node,spleen: 1.3 Cell line enhanced HeLa: 1.5;Karpas-707: 2.1 +RP11-507K12.1 ENSG00000283321 7 17299295-17467234 Predicted intracellular proteins Evidence at transcript level HPA029722 Uncertain Group enriched 5 cervix, uterine: 12.8;urinary bladder: 23.3 fallopian tube: 3.3 Cell line enriched 5 RT4: 44.0 +RP11-235D19.4 ENSG00000283324 1 150887136-150913292 Predicted membrane proteins Evidence at transcript level Not detected fallopian tube: 0.8 Cell line enriched 6 BEWO: 1.1 +RP13-198D9.4 ENSG00000283329 9 38694263-38720428 Predicted intracellular proteins No evidence Not detected testis: 0.8 Not detected +RP11-569D9.5 ENSG00000283361 13 114179238-114223084 Predicted intracellular proteins Evidence at transcript level Tissue enriched 16 fallopian tube: 15.8 testis: 0.9 Not detected +TXNRD3NB TR2IT1, TXNRD3IT1, TXNRD3NT1 ENSG00000283374 Thioredoxin reductase 3 neighbor 3 126571779-126608555 Predicted intracellular proteins Evidence at transcript level HPA058257 Uncertain Not detected parathyroid gland,testis: 0.1 Not detected +CH17-296N19.1 ENSG00000283378 9 61330717-61453030 Predicted secreted proteins Evidence at transcript level Tissue enriched 7 bone marrow: 7.3 testis: 0.9 Group enriched 6 A549: 24.8;SiHa: 6.4;TIME: 7.0;WM-115: 23.6 +RP11-153I24.5 ENSG00000283384 13 108335354-108448316 Predicted intracellular proteins Evidence at transcript level Mixed testis: 1.2 Not detected +RP11-811O14.1 ENSG00000283428 2 224703764-224716365 Predicted intracellular proteins Evidence at transcript level Not detected tonsil: 0.2 Cell line enhanced Daudi: 1.7 +RP11-249L12.1 ENSG00000283434 3 88338413-88467562 Predicted intracellular proteins Evidence at transcript level Tissue enriched 411 testis: 41.1 all non-specific tissues: 0.0 Not detected +RP11-104H15.12 ENSG00000283439 17 7428903-7432762 Predicted membrane proteins Evidence at transcript level Tissue enriched 285 testis: 28.5 all non-specific tissues: 0.0 Not detected +XX-FW81066F1.2 ENSG00000283463 X 149929645-149931287 Predicted intracellular proteins Evidence at transcript level Group enriched 33 adrenal gland: 4.8;testis: 17.6 skin: 0.3 Not detected +RP11-509I21.2 ENSG00000283473 Uncharacterized protein LOC100132146 3 46612435-46626543 Predicted intracellular proteins No evidence Not detected breast: 0.4 Not detected +ZNF511-PRAP1 ENSG00000283496 ZNF511-PRAP1 readthrough 10 133309410-133352529 Predicted membrane proteins Evidence at protein level HPA035360, HPA038713, HPA052451 Supported Uncertain Nucleoplasm
Vesicles
Plasma membrane Tissue enhanced duodenum: 25.2;small intestine: 25.0 kidney: 10.7 Cell line enhanced Hep G2: 11.3 +RP11-77H9.1 ENSG00000283516 16 8881634-8885351 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Tissue enriched 6 testis: 6.9 skin: 1.1 Not detected +RP11-40A7.2 ENSG00000283526 9 131545514-131558620 Predicted membrane proteins Evidence at transcript level Tissue enhanced fallopian tube: 10.2;lung: 6.2 prostate: 4.0 Group enriched 11 A549: 13.2;BEWO: 9.2;MCF7: 3.0;T-47d: 6.8 +RP11-298A10.1 ENSG00000283528 7 143639230-143647646 Predicted intracellular proteins Evidence at protein level HPA038756, HPA038758 Uncertain Not detected placenta: 0.3 Not detected +RP11-624J6.2 ENSG00000283536 12 53241889-53245134 Predicted intracellular proteins No evidence Not detected skin: 0.2 Not detected +CTD-2537I9.19 ENSG00000283567 19 55463002-55464707 Predicted intracellular proteins Evidence at transcript level Not detected lung,seminal vesicle,testis: 0.2 Cell line enriched 104 NTERA-2: 10.3 +FAM236C ENSG00000283594 Family with sequence similarity 236 member C X 72912615-72913401 Predicted intracellular proteins Evidence at transcript level Tissue enriched 62 testis: 6.2 all non-specific tissues: 0.0 Not detected +FAM169B FLJ39743, KIAA0888L ENSG00000283597 Family with sequence similarity 169 member B 15 98437162-98547728 Predicted intracellular proteins Evidence at transcript level Not detected testis: 0.1 Not detected +RP11-402P6.15 ENSG00000283599 X 71667542-71671524 Predicted intracellular proteins Evidence at transcript level Tissue enriched 24 testis: 9.5 cerebral cortex: 0.3 Not detected +EXOC3L2 FLJ36147, XTP7 ENSG00000283632 Exocyst complex component 3 like 2 19 45212621-45245431 Predicted intracellular proteins Evidence at protein level Mixed spleen: 11.0 Group enriched 7 HEL: 17.8;K-562: 16.7 +RP13-210D15.9 ENSG00000283644 X 135309480-135309659 Predicted intracellular proteins Evidence at transcript level Tissue enhanced seminal vesicle: 1.1;skin: 1.4 thyroid gland: 0.6 Not detected +RP11-244E17.1 ENSG00000283654 14 23099065-23104992 Predicted membrane proteins Evidence at transcript level Not detected testis: 0.7 Cell line enriched 10 HSkMC: 2.2 +RP3-454G6.2 ENSG00000283683 1 171600621-171638799 Predicted intracellular proteins Evidence at transcript level Tissue enhanced cervix, uterine: 8.0;fallopian tube: 4.6 epididymis: 4.1 Cell line enriched 6 HEL: 24.8 +RP5-937E21.8 ENSG00000283697 X 149548210-149549932 Predicted intracellular proteins Evidence at transcript level Tissue enriched 7 testis: 17.3 adrenal gland: 2.3 Not detected +RP11-680F20.6 ENSG00000283703 11 125946056-125956319 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Tissue enriched 9 skin: 20.9 breast: 2.2 Not detected +PRSS50 CT20, TSP50 ENSG00000283706 Protease, serine 50 3 46712115-46717907 Enzymes, Predicted secreted proteins Evidence at protein level HPA040768 Supported Tissue enriched 14 testis: 38.7 thyroid gland: 2.7 Cell line enhanced HMC-1: 1.2 +RP11-432M8.22 ENSG00000283740 5 17604177-17605377 Predicted intracellular proteins Evidence at transcript level Not detected testis: 0.5 Cell line enhanced U-2 OS: 1.0 +CPHXL ENSG00000283755 Cytoplasmic polyadenylated homeobox like 16 75714224-75726442 Predicted intracellular proteins Evidence at transcript level Tissue enriched 10 testis: 1.0 all non-specific tissues: 0.0 Not detected +LLNLR-275H8.1 ENSG00000283758 19 35586260-35587296 Predicted membrane proteins Evidence at transcript level Tissue enriched 17 testis: 1.7 all non-specific tissues: 0.0 Not detected +RP4-714D9.5 ENSG00000283761 1 99970011-100083321 Predicted membrane proteins Evidence at transcript level HPA073681 Approved Vesicles Mixed lung: 1.0 Mixed +RP11-449K6.5 ENSG00000283765 3 183815568-183884889 Predicted membrane proteins Evidence at protein level HPA019545 Uncertain Approved Mitochondria Tissue enhanced cerebral cortex: 3.4;testis: 2.1 adrenal gland,esophagus,skeletal muscle: 0.6 Cell line enhanced T-47d: 7.0 +RP11-432M8.12 ENSG00000283776 5 17632088-17632684 Predicted intracellular proteins No evidence Not detected all non-specific tissues: 0.0 Not detected +PRR33 C11orf89, LOC728008 ENSG00000283787 Proline rich 33 11 1888577-1891895 Predicted intracellular proteins Evidence at transcript level Tissue enhanced skin: 12.2 skeletal muscle,spleen: 11.5 Cell line enhanced Daudi: 2.2;HDLM-2: 8.1;Karpas-707: 4.1;U-937: 3.4 +AC007326.13 ENSG00000283809 22 18906238-18947732 Predicted intracellular proteins Evidence at transcript level Expressed in all cerebral cortex: 23.0 Expressed in all +SSU72P4 ENSG00000283873 SSU72 pseudogene 4 11 4287499-4288083 Predicted intracellular proteins No evidence Not detected rectum: 0.2 Not detected +RP1-5O6.7 ENSG00000283900 Casein kinase I isoform epsilon 22 38291918-38398522 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA026288 Uncertain Tissue enhanced parathyroid gland: 6.5 cerebral cortex: 2.6 Cell line enhanced Karpas-707: 5.1 +RP11-543B16.5 ENSG00000283952 1 211082872-211188533 Predicted intracellular proteins No evidence Not detected testis: 0.7 Not detected +RP11-432M8.3 ENSG00000283967 5 17590364-17590960 Predicted intracellular proteins No evidence Not detected all non-specific tissues: 0.0 Not detected +CTD-2659N19.11 ENSG00000283980 19 12687998-12688422 Predicted intracellular proteins Evidence at transcript level Tissue enhanced skin: 1.2;testis: 1.6 thyroid gland: 0.8 Cell line enhanced HEK 293: 2.0;MCF7: 1.6 +RP11-432M8.4 ENSG00000283988 5 17593798-17594394 Predicted intracellular proteins No evidence Not detected all non-specific tissues: 0.0 Not detected +LYNX1 ENSG00000283992 Ly6/neurotoxin 1 8 142764338-142769844 Predicted secreted proteins, Transporters Evidence at protein level Group enriched 11 esophagus: 315.6;skin: 108.1 tonsil: 19.9 Group enriched 16 EFO-21: 5.6;HaCaT: 24.1 +SSU72P5 ENSG00000284018 SSU72 pseudogene 5 11 4233288-4233872 Predicted intracellular proteins No evidence Not detected rectum,smooth muscle: 0.1 Not detected +RP11-398C13.8 ENSG00000284024 10 14838166-14844727 Predicted intracellular proteins Evidence at transcript level Mixed testis: 8.8 Expressed in all +RP11-511P7.7 ENSG00000284041 7 150368790-150396915 Predicted intracellular proteins Evidence at transcript level Tissue enhanced parathyroid gland: 2.1 endometrium: 1.0 Cell line enhanced RPMI-8226: 4.0;SH-SY5Y: 5.5 +RP11-321E2.9 ENSG00000284042 5 17528669-17529265 Predicted intracellular proteins No evidence Not detected all non-specific tissues: 0.0 Not detected +RP11-606E8.2 ENSG00000284057 11 93741664-93812378 Predicted intracellular proteins Evidence at protein level HPA040511, HPA064236 Approved Approved Nucleoplasm
Vesicles Tissue enhanced kidney: 6.9 duodenum: 3.1 Mixed +RP11-173A6.4 ENSG00000284188 1 244730375-244730962 Predicted intracellular proteins Evidence at transcript level Tissue enriched 8 testis: 1.5 kidney,parathyroid gland: 0.1 Not detected +SCO2 ENSG00000284194 SCO2, cytochrome c oxidase assembly protein 22 50523568-50526439 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046943, HPA056254 Uncertain Approved Mitochondria Tissue enhanced bone marrow: 5.3 spleen: 2.7 Mixed +RP11-321E2.8 ENSG00000284234 5 17525235-17525831 Predicted intracellular proteins Evidence at transcript level Tissue enriched 12 testis: 1.2 all non-specific tissues: 0.0 Not detected +RP11-321E2.7 ENSG00000284283 5 17521801-17522397 Predicted intracellular proteins No evidence Not detected all non-specific tissues: 0.0 Not detected +RP5-900K19.2 ENSG00000284292 7 99325879-99394653 Predicted intracellular proteins Evidence at protein level HPA004334 Uncertain Approved Cell Junctions
Cytosol Mixed appendix: 3.3 Mixed +RP11-434N15.2 ENSG00000284299 1 210858125-211134146 Predicted membrane proteins Evidence at transcript level Not detected cerebral cortex: 0.6 Cell line enhanced SH-SY5Y: 1.3 +SSU72P2 ENSG00000284306 SSU72 pseudogene 2 11 4242056-4242640 Predicted intracellular proteins No evidence Not detected all non-specific tissues: 0.0 Not detected +C2orf81 hCG40743, LOC388963 ENSG00000284308 Chromosome 2 open reading frame 81 2 74414176-74421591 Predicted intracellular proteins Evidence at protein level HPA049564, HPA054835 Enhanced Approved Nucleus
Nucleoli fibrillar center Tissue enhanced fallopian tube: 28.5;testis: 23.0 parathyroid gland: 7.9 Cell line enhanced SCLC-21H: 20.9;SH-SY5Y: 20.5 +RP11-432M8.5 ENSG00000284356 5 17597232-17597828 Predicted intracellular proteins Evidence at transcript level Tissue enriched 12 testis: 1.2 all non-specific tissues: 0.0 Not detected +RP11-321E2.6 ENSG00000284373 Putative TAF11-like protein ENSP00000332601 5 17498231-17498827 Predicted intracellular proteins No evidence Not detected testis: 0.2 Not detected +LA16c-312E8.5 ENSG00000284395 16 1431035-1433397 Predicted intracellular proteins Evidence at transcript level Tissue enhanced prostate: 2.6;stomach: 1.4 duodenum: 0.7 Cell line enriched 54 SCLC-21H: 38.7 +BTBD8 ENSG00000284413 BTB domain containing 8 1 92080305-92147840 Predicted intracellular proteins Evidence at transcript level HPA035311, HPA035312 Uncertain Approved Nucleoplasm Not detected lung: 0.3 Not detected +SSU72P7 ENSG00000284438 SSU72 pseudogene 7 11 4338660-4339244 Predicted intracellular proteins No evidence Not detected all non-specific tissues: 0.0 Not detected +RP11-321E2.2 ENSG00000284439 5 17518367-17518963 Predicted intracellular proteins No evidence Not detected all non-specific tissues: 0.0 Not detected +RABGEF1 ENSG00000284461 RAB guanine nucleotide exchange factor 1 7 66628958-66811459 Predicted intracellular proteins Evidence at transcript level Mixed adrenal gland: 8.8 Mixed +RP11-432M8.2 ENSG00000284465 5 17585162-17585758 Predicted intracellular proteins No evidence Not detected testis: 0.2 Not detected +AC009477.8 ENSG00000284479 2 131035092-131035262 Predicted membrane proteins Evidence at transcript level Tissue enriched 8 adipose tissue: 1.1 colon,small intestine: 0.1 Cell line enhanced HEK 293: 1.4 +RP11-490B18.9 ENSG00000284484 16 75660227-75677009 Predicted intracellular proteins No evidence Not detected skin: 0.1 Not detected +CTD-2265O21.8 ENSG00000284491 19 12802072-12804303 Predicted secreted proteins No evidence Not detected testis: 0.6 Not detected +LYNX1 ENSG00000284505 Ly6/neurotoxin 1 8 142764334-142778224 Predicted secreted proteins, Transporters Evidence at protein level Tissue enhanced esophagus: 5.8 skin: 4.0 Not detected +RP11-303E16.10 ENSG00000284512 16 81022316-81096284 Predicted secreted proteins Evidence at protein level HPA041368 Uncertain Approved Vesicles Tissue enriched 7 testis: 12.0 cerebral cortex: 1.6 Mixed +RP11-666A8.13 ENSG00000284526 17 76563710-76570544 Predicted intracellular proteins Evidence at transcript level Mixed skin: 20.6 Mixed +SSU72P3 ENSG00000284546 SSU72 pseudogene 3 11 4329865-4330449 Predicted intracellular proteins No evidence Not detected all non-specific tissues: 0.0 Not detected +RP11-321E2.5 ENSG00000284552 5 17486231-17486829 Predicted intracellular proteins Evidence at transcript level Not detected epididymis: 0.4 Cell line enriched 12 U-937: 2.5 +CTA-150C2.22 ENSG00000284554 DNA dC->dU-editing enzyme APOBEC-3D 22 39014363-39033276 Predicted intracellular proteins Evidence at protein level HPA055116 Approved Mixed fallopian tube: 3.8 Cell line enhanced fHDF/TERT166: 2.7;HHSteC: 3.4;HSkMC: 2.1;hTEC/SVTERT24-B: 2.0;Karpas-707: 3.5 diff -r 0b279190f90d -r 133309fd6875 tool_data_table_conf.xml.sample --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_data_table_conf.xml.sample Fri Jan 24 04:22:48 2020 -0500 @@ -0,0 +1,6 @@ + + + id, release, name, tissue, value + +
+ \ No newline at end of file